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Search of human proteins with 37537554
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
(841 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] 1747 0.0
gi|153792764 hypothetical protein LOC57624 [Homo sapiens] 209 9e-54
gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens] 209 9e-54
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens] 149 1e-35
gi|163965366 nascent polypeptide-associated complex alpha subuni... 105 2e-22
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 94 7e-19
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 85 3e-16
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 85 3e-16
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 82 3e-15
gi|18959210 WIRE protein [Homo sapiens] 73 1e-12
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 71 4e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 5e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 71 5e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 70 1e-11
gi|160707881 formin 2 [Homo sapiens] 68 3e-11
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 68 3e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 68 4e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 68 4e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 68 4e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 68 4e-11
gi|55750053 atrophin-1 [Homo sapiens] 68 4e-11
gi|55750041 atrophin-1 [Homo sapiens] 68 4e-11
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 67 7e-11
gi|110832843 TBP-associated factor 4 [Homo sapiens] 66 1e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 66 2e-10
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 65 2e-10
gi|18079216 CASK interacting protein 1 [Homo sapiens] 64 4e-10
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 63 1e-09
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 62 2e-09
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 62 2e-09
>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
Length = 841
Score = 1747 bits (4524), Expect = 0.0
Identities = 841/841 (100%), Positives = 841/841 (100%)
Query: 1 MNLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGF 60
MNLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGF
Sbjct: 1 MNLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGF 60
Query: 61 MTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRR 120
MTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRR
Sbjct: 61 MTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRR 120
Query: 121 HPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESC 180
HPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESC
Sbjct: 121 HPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESC 180
Query: 181 PPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLG 240
PPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLG
Sbjct: 181 PPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLG 240
Query: 241 GGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAH 300
GGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAH
Sbjct: 241 GGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAH 300
Query: 301 RRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVL 360
RRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVL
Sbjct: 301 RRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVL 360
Query: 361 CHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRG 420
CHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRG
Sbjct: 361 CHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRG 420
Query: 421 ERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPP 480
ERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPP
Sbjct: 421 ERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPP 480
Query: 481 LGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDP 540
LGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDP
Sbjct: 481 LGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDP 540
Query: 541 TVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMVKIQLQEQGTDGGAF 600
TVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMVKIQLQEQGTDGGAF
Sbjct: 541 TVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMVKIQLQEQGTDGGAF 600
Query: 601 ASISCAHVIASAGTPEEEEEEVGAATFGAGWALQRKVLYGGRKAKELDKVEDGARAWNGS 660
ASISCAHVIASAGTPEEEEEEVGAATFGAGWALQRKVLYGGRKAKELDKVEDGARAWNGS
Sbjct: 601 ASISCAHVIASAGTPEEEEEEVGAATFGAGWALQRKVLYGGRKAKELDKVEDGARAWNGS 660
Query: 661 AEGPGKVEREDRGPGTSGIPVRSQGAEGLLARIHHGDRGGSRTALPIPCQTFPACHRNGD 720
AEGPGKVEREDRGPGTSGIPVRSQGAEGLLARIHHGDRGGSRTALPIPCQTFPACHRNGD
Sbjct: 661 AEGPGKVEREDRGPGTSGIPVRSQGAEGLLARIHHGDRGGSRTALPIPCQTFPACHRNGD 720
Query: 721 FTGGYRLGRSASTSGVRQVVLHTPRPCSQPRDALSQPHPALPLPLPLPPQPARERDGKLL 780
FTGGYRLGRSASTSGVRQVVLHTPRPCSQPRDALSQPHPALPLPLPLPPQPARERDGKLL
Sbjct: 721 FTGGYRLGRSASTSGVRQVVLHTPRPCSQPRDALSQPHPALPLPLPLPPQPARERDGKLL 780
Query: 781 EVIERKRCVCKEIKARHRPDRGLCKQESMPILPSWRRGPEPRKSGTPPCRRQHTVLWDTA 840
EVIERKRCVCKEIKARHRPDRGLCKQESMPILPSWRRGPEPRKSGTPPCRRQHTVLWDTA
Sbjct: 781 EVIERKRCVCKEIKARHRPDRGLCKQESMPILPSWRRGPEPRKSGTPPCRRQHTVLWDTA 840
Query: 841 I 841
I
Sbjct: 841 I 841
>gi|153792764 hypothetical protein LOC57624 [Homo sapiens]
Length = 653
Score = 209 bits (532), Expect = 9e-54
Identities = 160/451 (35%), Positives = 206/451 (45%), Gaps = 95/451 (21%)
Query: 2 NLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFM 61
NL Y K K E R+ +EE KR G G+G + + + + RMGFM
Sbjct: 54 NLAYLKEKNEKRRRQEEAIKR-----------IGGEVGRG-----HEGSYVGKHFRMGFM 97
Query: 62 TMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRH 121
TMPA Q+ PHPC S + RS S HSVG D +S G S R+PP KP+R
Sbjct: 98 TMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDD------DSSCG-----SRRQPPPKPKRD 146
Query: 122 PSTKLSMVGP------GSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVS 175
PSTKLS S + P + S KP P E S+K+PP KP+R+PNTQLS S
Sbjct: 147 PSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTS 206
Query: 176 FDESCPPGPSPRGGNLPL-QRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGL 234
FDE+ PR +LP L++ AGDP+ +EEPVYIEMVG++ R +
Sbjct: 207 FDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPE---EEEPVYIEMVGNILRDFRK----- 258
Query: 235 AGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHA 294
D ++SEA+YEEMKYP+ ++ G+ + +S P
Sbjct: 259 -----------------EDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTV 301
Query: 295 LPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGD-- 352
P AS P K C+IPPPFPNLL HRPPLL FP A D
Sbjct: 302 --PDLDFAKASV------PCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDES 353
Query: 353 -----GVSRLPVL---CHSKEPAGSTP------------------APQVPARERETPPPP 386
V++LPVL + K+PAG++P A PA
Sbjct: 354 PLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS 413
Query: 387 PPPPAANLLLLGPSGRARSHSTPLPPQGSGQ 417
PPPP+ P G +SHST P G+
Sbjct: 414 PPPPSTLYRTQSPHGYPKSHSTSPSPVSMGR 444
Score = 55.5 bits (132), Expect = 2e-07
Identities = 104/398 (26%), Positives = 148/398 (37%), Gaps = 84/398 (21%)
Query: 362 HSKEPAGSTPA-PQVPARERETPPPPP------PPPAANLLLLGPSGRARSHSTPLPPQG 414
HS +TP P + + P PP PPP NLL SH PL
Sbjct: 290 HSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLL---------SHRPPL---- 336
Query: 415 SGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSV 474
P + P + +P P L P + VSY + +T
Sbjct: 337 -------LVFPPAPVHCSPNSDESPLTPLEVTKL----PVLENVSYMKQPAGASPST--- 382
Query: 475 LPAGPPLGAGEPKTEKEISVLHGMLCT----SSRPPVPGKT----SPHGGAMGAAAGVLH 526
LP+ P G K EKE + G SS PP P SPHG +
Sbjct: 383 LPSHVP---GHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHG----------Y 429
Query: 527 HRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMV 586
+ SP P LTPL LKRPP Y+++ +G + V +P
Sbjct: 430 PKSHSTSPS--PVSMGRSLTPL--------SLKRPPPYDAVHSGSLSRSSPSVPHSTPRP 479
Query: 587 KIQLQEQGTDGGAFASISCAHVIASAG-----TPEEEEEEVGAATFGAGWALQRKVLYGG 641
Q DG + + A+ G TP EE+ + F +G +L RK G
Sbjct: 480 VSQ------DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEEL-TSLFSSGRSLLRKSSSGR 532
Query: 642 RKAKELDKVEDGARAWNGSAEGPGKVEREDR---GPGTSGIPVRSQGAEGLLARIHHGDR 698
R + +K + + + S E K++ ++R G +S PV++Q +G R
Sbjct: 533 RSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSR 592
Query: 699 GGSRTALPIPCQTFPACHRNGDFTGGYRLGRSASTSGV 736
G + P T A + + + +LGRSASTSGV
Sbjct: 593 LGRCSVSP----TLLAGNHSSEPKVSCKLGRSASTSGV 626
>gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]
Length = 669
Score = 209 bits (532), Expect = 9e-54
Identities = 160/451 (35%), Positives = 206/451 (45%), Gaps = 95/451 (21%)
Query: 2 NLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFM 61
NL Y K K E R+ +EE KR G G+G + + + + RMGFM
Sbjct: 54 NLAYLKEKNEKRRRQEEAIKR-----------IGGEVGRG-----HEGSYVGKHFRMGFM 97
Query: 62 TMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRH 121
TMPA Q+ PHPC S + RS S HSVG D +S G S R+PP KP+R
Sbjct: 98 TMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDD------DSSCG-----SRRQPPPKPKRD 146
Query: 122 PSTKLSMVGP------GSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVS 175
PSTKLS S + P + S KP P E S+K+PP KP+R+PNTQLS S
Sbjct: 147 PSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTS 206
Query: 176 FDESCPPGPSPRGGNLPL-QRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGL 234
FDE+ PR +LP L++ AGDP+ +EEPVYIEMVG++ R +
Sbjct: 207 FDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPE---EEEPVYIEMVGNILRDFRK----- 258
Query: 235 AGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHA 294
D ++SEA+YEEMKYP+ ++ G+ + +S P
Sbjct: 259 -----------------EDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTV 301
Query: 295 LPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGD-- 352
P AS P K C+IPPPFPNLL HRPPLL FP A D
Sbjct: 302 --PDLDFAKASV------PCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDES 353
Query: 353 -----GVSRLPVL---CHSKEPAGSTP------------------APQVPARERETPPPP 386
V++LPVL + K+PAG++P A PA
Sbjct: 354 PLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS 413
Query: 387 PPPPAANLLLLGPSGRARSHSTPLPPQGSGQ 417
PPPP+ P G +SHST P G+
Sbjct: 414 PPPPSTLYRTQSPHGYPKSHSTSPSPVSMGR 444
Score = 46.6 bits (109), Expect = 1e-04
Identities = 89/350 (25%), Positives = 128/350 (36%), Gaps = 80/350 (22%)
Query: 362 HSKEPAGSTPA-PQVPARERETPPPPP------PPPAANLLLLGPSGRARSHSTPLPPQG 414
HS +TP P + + P PP PPP NLL SH PL
Sbjct: 290 HSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLL---------SHRPPL---- 336
Query: 415 SGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSV 474
P + P + +P P L P + VSY + +T
Sbjct: 337 -------LVFPPAPVHCSPNSDESPLTPLEVTKL----PVLENVSYMKQPAGASPST--- 382
Query: 475 LPAGPPLGAGEPKTEKEISVLHGMLCT----SSRPPVPGKT----SPHGGAMGAAAGVLH 526
LP+ P G K EKE + G SS PP P SPHG +
Sbjct: 383 LPSHVP---GHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHG----------Y 429
Query: 527 HRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMV 586
+ SP P LTPL LKRPP Y+++ +G + V +P
Sbjct: 430 PKSHSTSPS--PVSMGRSLTPL--------SLKRPPPYDAVHSGSLSRSSPSVPHSTPRP 479
Query: 587 KIQLQEQGTDGGAFASISCAHVIASAG-----TPEEEEEEVGAATFGAGWALQRKVLYGG 641
Q DG + + A+ G TP EE+ + F +G +L RK G
Sbjct: 480 VSQ------DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEEL-TSLFSSGRSLLRKSSSGR 532
Query: 642 RKAKELDKVEDGARAWNGSAEGPGKVEREDR---GPGTSGIPVRSQGAEG 688
R + +K + + + S E K++ ++R G +S PV++Q +G
Sbjct: 533 RSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDG 582
Score = 30.0 bits (66), Expect = 9.3
Identities = 53/229 (23%), Positives = 79/229 (34%), Gaps = 36/229 (15%)
Query: 247 PAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPP-------QQPHALPPHA 299
PAGA + S + K + A G A+ P L+++ PP Q PH P +
Sbjct: 375 PAGASPSTLPSH-VPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPK-S 432
Query: 300 HRRPASALPSRRDGTPTKTTPCEIPPPFPNL----LQHRPPLLAFPQAKSASRTPGDGVS 355
H S + R TP + PPP+ + L P + + S+ G +
Sbjct: 433 HSTSPSPVSMGRSLTPLSL---KRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQD-GAKMV 488
Query: 356 RLPVLCHSKEPAGS-TPAPQVPARERETPPPPPPPPAANLLLLGPSGR------------ 402
V + P GS + P P E + +LL SGR
Sbjct: 489 NAAVNTYGAAPGGSRSRTPTSPLEELTSLFSS----GRSLLRKSSSGRRSKEPAEKSTEE 544
Query: 403 --ARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALL 449
RSHST P+ + RG +S + + PP + L
Sbjct: 545 LKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRL 593
>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
Length = 1858
Score = 149 bits (376), Expect = 1e-35
Identities = 161/527 (30%), Positives = 210/527 (39%), Gaps = 118/527 (22%)
Query: 1 MNLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGF 60
MN Y K KLE R +EE +KR+ K +GP R
Sbjct: 1218 MNAPYHKEKLEVRNMQEEGSKRTDDK-------SGP-----------------RHFHPSS 1253
Query: 61 MTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRR 120
M++ A+ + C + S S HSV SMD P S ++PP KP+R
Sbjct: 1254 MSVCAAVDGLGQ-CLVGPSIWSPSLHSVFSMDDSSSLP----------SPRKQPPPKPKR 1302
Query: 121 HPSTKLSMVGPGSGAETPPSKKAGSQ---KPTPEGRESS--RKVPPQKPRRSPNTQLSVS 175
P+T+LS A +++A ++ +P P + S +K+PP+KP+RSPNT+LS S
Sbjct: 1303 DPNTRLSASYEAVSACLSAAREAANEALARPRPHSDDYSTMKKIPPRKPKRSPNTKLSGS 1362
Query: 176 FDE---SCPPGPSPRGGNLPLQR-LTRGS-----RVAGDPDVGAQEEPVYIEMVGDVFRG 226
++E S P P G R LT G+ A P EPVYIEM+G R
Sbjct: 1363 YEEISGSRPGDARPAGAPGAAARVLTPGTPQCALPPAAPPGDEDDSEPVYIEMLGHAAR- 1421
Query: 227 GGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTAT 286
P P + E++YEEMK LP++ G G G L
Sbjct: 1422 -----------------PDSP-------DPGESVYEEMKCCLPDDGGPGA--GSFLLHGA 1455
Query: 287 SPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSA 346
SPP A A P A C+IPPPFPNLL HRPPLL FP
Sbjct: 1456 SPPLLHRAPEDEAAGPPGDA--------------CDIPPPFPNLLPHRPPLLVFPPTPVT 1501
Query: 347 SRTPGD-------GVSRLPV----LCHSKEPAGSTP-APQVPARERETPPPPPPPPAANL 394
D V +LPV L + +P GS+P +PQ ++ P P L
Sbjct: 1502 CSPASDESPLTPLEVKKLPVLETNLKYPVQPEGSSPLSPQYSKSQKGDGDRPASP---GL 1558
Query: 395 LLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLP---- 450
L SGRA STP PP P P +H P+ A A P+A P
Sbjct: 1559 ALFNGSGRASPPSTPPPPPPPPGPPPAPYRPCAHLAFPPEPAPVNAGKAGPSAEAPKVHP 1618
Query: 451 ----GPPKDKAVSYTMV-YSAVKVTTHSVLPAG----PPLGAGEPKT 488
P S+ + YS VK T AG PP P +
Sbjct: 1619 KPNSAPVAGPCSSFPKIPYSPVKATRADARKAGSSASPPAPYSPPSS 1665
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 105 bits (262), Expect = 2e-22
Identities = 154/576 (26%), Positives = 187/576 (32%), Gaps = 99/576 (17%)
Query: 32 GSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSAMAPRSLSCHSVGSM 91
G A PA Q P + + + + +PAS P A P S
Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK------- 951
Query: 92 DSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPE 151
GGP S PP+ P+ P+T P A TPPS K G P+P+
Sbjct: 952 ----GGPATPSPKWAPTPPAATPPS-PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006
Query: 152 GRESSRKVPPQKPRRSPNTQLSVSFDESCPPG---PSPRG--GNLPLQRLTRGSRVAGDP 206
G + V P P+ SP S PP PSP+G PL + G P
Sbjct: 1007 GAPTPPAVTPPSPKGSP-AATPFPKGASTPPAATPPSPKGSPAATPLPK--------GAP 1057
Query: 207 DVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKY 266
A P GG A P L G PTPPA + A
Sbjct: 1058 TTPAATLP--------------SPKGGPATPSL-KGAPTPPAATPPSPKGGPAT------ 1096
Query: 267 PLPEEAGEGRANGPPPLTATSP-PQQPHALPPH--AHRRPASALPSRRDGTPT------K 317
P P+ A P P AT P P+ A PPH A PA+ PS + G T
Sbjct: 1097 PSPKGA-------PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Query: 318 TTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPA 377
TTP PP L PP K A TP P G P P
Sbjct: 1150 TTPAATPPSPKGGLATPPP-------KGAPTTPA---------ATPPSPKGGLATPS-PK 1192
Query: 378 RERETPPPPPPPPAANLLLLGPSGRARS-HSTPLPPQGSGQPRGERELPNSHSMICPKAA 436
TP PP P L P G + +TP P+G + P + + P
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 437 GAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLP----AGPPLGAGEPKTEKEI 492
G PA PP A P PP A + + + H P PP G P T
Sbjct: 1253 GGPATPPPKGA--PTPP---AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307
Query: 493 SVLHGMLCTSSRPP-VPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTPLWTY 551
T P PG P G A +G P + P GP T
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT----- 1362
Query: 552 PATAAGLKRPPAYESLKAGGVLNKGC---GVGAPSP 584
P++ G P A S K G + G PSP
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398
Score = 79.3 bits (194), Expect = 1e-14
Identities = 142/584 (24%), Positives = 195/584 (33%), Gaps = 84/584 (14%)
Query: 29 APAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSAMA-PRSLSCHS 87
+P G+ P A P + A+ G T PA+ +P +A P+
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAAT---PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 88 VGSMDSVGGGPGGAS--GGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGS 145
++ S GGP S G T ++T P P+ P+T P A TPPS K G
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAAT---PPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117
Query: 146 QKPTPEGRESSRKVPPQKPR---RSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRV 202
P +G ++ P P+ +P + + + + PP SP+GG +
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGG------------L 1163
Query: 203 AGDPDVGAQEEPVYIE------MVGDVFRGGGRSGGGLAGPPLGG-------GGPTPPAG 249
A P GA P + +G + P GG G PT PA
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 250 ADSDSEESEAIYEEMKYPLPEEAGEGRANG----PPPLTATSPPQQPH-------ALPPH 298
+ A P A G PPP A +PP A PPH
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 299 AHR-RPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRL 357
PA P G P + P P P P P K + TP +
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTP---------PAATPPSPKGSPGTPPPKGAPT 1334
Query: 358 PVLCHSKEPAGSTPAPQVPARERETPPPP-----PPPPAANLLLLGPSGRARSHSTPLPP 412
P P G+ P + P P P PPAA PS + TP P
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT-----PSHKGGPAMTPPSP 1389
Query: 413 Q---GSGQPRGERELPNSHSMICPKAAGAP-----AAPPAPAALLPGPPKDKAVSYTMVY 464
+ P+G+ P + KA P AA P+ L P ++
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
Query: 465 SAVKVTTHSVLPAG-PPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAG 523
SA K + G P L A P + KE + +SS P +P G A
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
Query: 524 VLHHRGCLASPHSLPDPTVGPLTPLWT--YPATAAGLKR--PPA 563
+ A+P S DP + P L + PAT A + PPA
Sbjct: 1510 PSSPKEVPATPSSRRDP-IAPTATLLSKKTPATLAPKEALIPPA 1552
Score = 73.2 bits (178), Expect = 1e-12
Identities = 112/428 (26%), Positives = 154/428 (35%), Gaps = 66/428 (15%)
Query: 64 PASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPS 123
P TP P + A P +++ S ++ + GG T SS + P P PS
Sbjct: 1320 PKGSPGTPPP-KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS-KEGPTPPAATPS 1377
Query: 124 TKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQL------SVSFD 177
K G A TPPS K G P+P+G +S V P P+++P T + + S
Sbjct: 1378 HK------GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKG 1431
Query: 178 ESCPPGPSPRG-GNLPLQRLTRGSRVA----GDPDVGAQEEPVYIEMVGDVFRGGGRSGG 232
+ PP +P P +G GDP + A P E S
Sbjct: 1432 DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
Query: 233 GLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPL-----------PEEAGEGRANGPP 281
P G PT PA S +E A + P+ P A PP
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 282 PLTATSPPQQPHALPPHAHRRPASALPSRRD-GTPTKTTPCE---IPPPFPNLLQHRPPL 337
+T SP + P P + A A PS ++ +P TP P P L+ PP
Sbjct: 1552 AMTVPSPKKTPAIPTP----KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI---PPA 1604
Query: 338 LAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLL 397
+ P K A P V S E +TPAP + TP PP P++ L
Sbjct: 1605 VTSPSPKEAPTPPA-------VTPPSPEKGPATPAP------KGTPTSPPVTPSS--LKD 1649
Query: 398 GPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPK---AAGAPAAPP---APAALLPG 451
P+ S ++ G+ P+ + LP K A AP + P AP P
Sbjct: 1650 SPT----SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQ 1705
Query: 452 PPKDKAVS 459
K A S
Sbjct: 1706 TKKSSATS 1713
Score = 53.1 bits (126), Expect = 1e-06
Identities = 115/537 (21%), Positives = 167/537 (31%), Gaps = 78/537 (14%)
Query: 106 TEDSSTRRPPAKP--------RRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSR 157
T+ ++T R P P + PS+ L +T P+ G+ + +++
Sbjct: 495 TQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTK 554
Query: 158 KVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYI 217
K P P + S SF + P L + + G + + P+ +
Sbjct: 555 KDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGV 614
Query: 218 EMVGDVFRGGGRSGGGLAGPPLGGGGPTP-----------PAGADSDSEESEAIYEEMKY 266
V + +G AGP L TP PAG + + + Y
Sbjct: 615 NSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTAS 674
Query: 267 PLPEEAGEGRANGPP---------PLTATSPPQQPHALPPHAHRRPASAL---PSRRDGT 314
P E P PL T+ P A P P + L P
Sbjct: 675 PFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSV 734
Query: 315 PTKTTPCEIPPPFPNL---LQHRPPLLAFPQAKSASRTPGDGVS-------RLPVLCHSK 364
P+ + P PP + H L + T G S L L S
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 365 EPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGEREL 424
P G + +PQ + P P NL S P+ S +G ++
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNL-----SSPVSPVEASFLPENSLSFQGSKDS 849
Query: 425 P-NSHSMICPKAAGAPAAPPAPAALLPGPPKDKAV--SYTMVYSAVKVTTHSVLPAGPPL 481
P +HS P GA P P+A+ P PK + T S V + PA P
Sbjct: 850 PATTHSPTPPSPKGA----PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP-- 903
Query: 482 GAGEPKTEKEISVLHG----MLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPH-- 535
PK +S+ T + +P SP G AA +G A+P
Sbjct: 904 ---APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
Query: 536 --------SLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSP 584
+ P P GP TP + G PPA G GAP+P
Sbjct: 961 WAPTPPAATPPSPKGGPATP------SPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
Score = 52.8 bits (125), Expect = 1e-06
Identities = 105/481 (21%), Positives = 170/481 (35%), Gaps = 71/481 (14%)
Query: 64 PASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRP--PAKPRRH 121
P ++E P + + P +++ S+ + GG + ++ T P P+
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478
Query: 122 PSTKLSMVGPGSGAETPPSKKAGSQKPT-PEGRESSRKVPPQKP--RRSPNTQLSVSFDE 178
P+ K V S + P+ A PT P SS K P P RR P + +
Sbjct: 1479 PAPK--QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536
Query: 179 SCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPP 238
P +P+ +P + P + +E + S P
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKT--PAIPTPKEAPATPSSKEA------SSPPAVTPS 1588
Query: 239 LGGGGPTP-----PAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPH 293
G P+P P S S + + P PE+ G A P T TSPP P
Sbjct: 1589 TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK---GPATPAPKGTPTSPPVTPS 1645
Query: 294 ALPPHAHRRPASA--------------LPSRR--------------DGTPTKTTPCEIPP 325
+L + PAS LP+++ + TP T P P
Sbjct: 1646 SLKD-SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704
Query: 326 PFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPA------GSTPAPQVPARE 379
PP+ P AK+ S+ P V+ P+L K+ + ++ +P+ P
Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAP 1764
Query: 380 RETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQG--------SGQPRGERELPNSHSMI 431
E+ P AA +L A + P PP P ++ LP+S ++
Sbjct: 1765 PESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLV 1824
Query: 432 CPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPL---GAGEPKT 488
++ P AP LLP P + +S + + +V V + AG P+ A +P T
Sbjct: 1825 L-ESPSKPLAPADEDELLPLIPPE-PISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVT 1882
Query: 489 E 489
+
Sbjct: 1883 K 1883
Score = 33.5 bits (75), Expect = 0.85
Identities = 86/368 (23%), Positives = 125/368 (33%), Gaps = 40/368 (10%)
Query: 254 SEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPH-ALPPHAHRRPASALPSRRD 312
+E A +E+ P E A ++ L+ T+ QP LPP P S P +
Sbjct: 6 TETVPATEQELPQPQAETAVLPMSSA---LSVTAALGQPGPTLPP-----PCSPAPQQ-- 55
Query: 313 GTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPA 372
P P P P+ + P + FPQ+ S + P P + +PA
Sbjct: 56 -CPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPA 114
Query: 373 PQVPARERETPP-PPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMI 431
A P P +A L L+ + + S+ PP P + S S+I
Sbjct: 115 ALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSV-AVAESGSVI 173
Query: 432 CPKAAGAPAAP-----PAPAALLPGP---PKDKAVSYTMVYSAVKVTTHSVLPAGPPLGA 483
A AP+ P P+ ++P P P + T+ Y V S+ L
Sbjct: 174 TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV-TPMASIQSGVASLPQ 232
Query: 484 GEPKTEKEISVLHGMLCTSS----RPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLP- 538
P T I+ T S P PG S G AA L S SLP
Sbjct: 233 TTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSL-------STQSLPV 285
Query: 539 ----DPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMVKIQLQEQG 594
T GP TP +P + P S + +L + P VK +
Sbjct: 286 VTSSQKTAGPNTPP-DFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHS 344
Query: 595 TDGGAFAS 602
+ G ++ S
Sbjct: 345 STGASYPS 352
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 93.6 bits (231), Expect = 7e-19
Identities = 114/406 (28%), Positives = 142/406 (34%), Gaps = 78/406 (19%)
Query: 94 VGGGPGGASG-GLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEG 152
+ G P GA G + PP KP+ P G+ + PP Q P P+G
Sbjct: 32 IAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQG------GNQPQGPPPPPGKPQGPPPQG 85
Query: 153 RESSRKVPPQKPRRSPNTQLSVSFDESCPPG----PSPRGGNLPLQRLTRGSRVAGDPDV 208
+ PP + P Q S PPG P P+GGN P + G P
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 145
Query: 209 GAQE--------EPVYIEMVGDVFRGGGRSGGGLA-GPPLGGG----GPTPPAGADSDSE 255
G + +P GD RS G GPP GG GP PP G
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 205
Query: 256 ESEAIYEEMKYPLPEEAGEGRANGPPPL------TATSPPQQPHALPPHAHRRPASALP- 308
+ + P P G+ GPPP +A SPP +P PP +P P
Sbjct: 206 PQGG--NKPQGPPPP----GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259
Query: 309 -SRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPA 367
+ G P + PP P Q PP Q S SR+ S+ P
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPP-----QGGSKSRS-------------SRSPP 301
Query: 368 GST--PAPQVPARERETPPPPP-----PPPAANLLLLGPSGRARSHSTPLPPQGSGQPRG 420
G P PQ + + PPPPP PPP GP + P PQG + R
Sbjct: 302 GKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP--PQGGSKSRS 358
Query: 421 ERELP-----------NSHSMICPKAAGAPAAPPAPAALLP-GPPK 454
R P N+ P A G P P AP A P GPP+
Sbjct: 359 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 404
Score = 74.7 bits (182), Expect = 3e-13
Identities = 89/326 (27%), Positives = 113/326 (34%), Gaps = 48/326 (14%)
Query: 96 GGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRES 155
G P G + S R PP KP+ P G+ + PP Q P P+G
Sbjct: 96 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQG------GNQPQGPPPPPGKPQGPPPQGGNK 149
Query: 156 SRKVPPQ-KPRRSPNTQLSVSFDESCPPG----PSPRGGNLPLQRLTRGSRVAGDPDVGA 210
+ PP KP+ P + S PPG P P+GGN P + G P G
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 209
Query: 211 QE--------EPVYIEMVGDVFRGGGRSGGGLA-GPPLGGG----GPTPPAGADSDSEES 257
+ +P GD RS G GPP GG GP PP G
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269
Query: 258 EAIYEEMKYPLPEEAGEGRANGPPPL------TATSPPQQPHALPPHAHRRPASALP--S 309
+ + P P G+ GPPP ++ SPP +P PP +P P
Sbjct: 270 GG--NKPQGPPPP----GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323
Query: 310 RRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGS 369
+ G P + PP P Q PP +KS S G + P P G
Sbjct: 324 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGG---SKSRSARSPPGKPQGPPQQEGNNPQGP 380
Query: 370 TPA-------PQVPARERETPPPPPP 388
P PQ P + PP PP
Sbjct: 381 PPPAGGNPQQPQAPPAGQPQGPPRPP 406
Score = 73.2 bits (178), Expect = 1e-12
Identities = 100/397 (25%), Positives = 124/397 (31%), Gaps = 105/397 (26%)
Query: 136 ETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQR 195
E PS AG+ + P + + PP P + P GP P+GGN P
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGK--------------PQGPPPQGGNQPQGP 71
Query: 196 LTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSE 255
+ G P +GG + G PP G PP G S S
Sbjct: 72 PPPPGKPQGPPP-----------------QGGNKPQGP---PPPGKPQGPPPQGDKSRSP 111
Query: 256 ESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTP 315
S K P G + GPPP PP +P PP +P G P
Sbjct: 112 RSPP----GKPQGPPPQGGNQPQGPPP-----PPGKPQGPPPQGGNKP--------QGPP 154
Query: 316 TKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQV 375
P PP N KS S G + P +P G P P
Sbjct: 155 PPGKPQGPPPQGDN--------------KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 200
Query: 376 P-------ARERETPPPP-----PPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERE 423
P + + PPPP PPP N S + P PQG QP+G
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP--PQGGNQPQGPPP 258
Query: 424 LPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAG-PPLG 482
P P+ P PP P PP+ + S + K P G PP G
Sbjct: 259 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK-------PQGPPPQG 311
Query: 483 AGEPKTEKEISVLHGMLCTSSRPPVPGKTS---PHGG 516
+P+ PP PGK P GG
Sbjct: 312 GNQPQ---------------GPPPPPGKPQGPPPQGG 333
Score = 64.3 bits (155), Expect = 4e-10
Identities = 77/290 (26%), Positives = 98/290 (33%), Gaps = 64/290 (22%)
Query: 251 DSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALP-- 308
D EES ++ P + G + GPP SPP +P PP +P P
Sbjct: 22 DVSQEESPSLIAGNPQGAPPQGGN-KPQGPP-----SPPGKPQGPPPQGGNQPQGPPPPP 75
Query: 309 SRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAG 368
+ G P + PP P Q PP KS S G + P +P G
Sbjct: 76 GKPQGPPPQGGNKPQGPPPPGKPQGPPP----QGDKSRSPRSPPGKPQGPPPQGGNQPQG 131
Query: 369 STPAPQVP-------ARERETPPPP-----PPPPAANLLLLGPSGRARSHSTPL------ 410
P P P + + PPPP PPP N ++RS +P
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN--------KSRSSRSPPGKPQGP 183
Query: 411 PPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVT 470
PPQG QP+G P P+ P PP P PP+ S + K
Sbjct: 184 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGK-- 241
Query: 471 THSVLPAG-PPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTS---PHGG 516
P G PP G +P+ PP PGK P GG
Sbjct: 242 -----PQGPPPQGGNQPQ---------------GPPPPPGKPQGPPPQGG 271
Score = 59.3 bits (142), Expect = 1e-08
Identities = 64/226 (28%), Positives = 79/226 (34%), Gaps = 43/226 (19%)
Query: 98 PGGASG----GLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGR 153
PG G G + S R PP KP+ P G+ + PP Q P P+G
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG------GNQPQGPPPPPGKPQGPPPQGG 271
Query: 154 ESSRKVPPQ-KPRRSPNTQLSVSFDESCPPG----PSPRGGNLPLQRLTRGSRVAGDPDV 208
+ PP KP+ P S S PPG P P+GGN P + G P
Sbjct: 272 NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 331
Query: 209 GAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPL 268
G G GPP G PP S S + + + + P
Sbjct: 332 G---------------------GNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP- 369
Query: 269 PEEAGEGRANGPPPLTATSPPQQPHA----LPPHAHRRPASALPSR 310
P++ G PPP A PQQP A P R P PSR
Sbjct: 370 PQQEGNNPQGPPPP--AGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 413
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 84.7 bits (208), Expect = 3e-16
Identities = 104/388 (26%), Positives = 130/388 (33%), Gaps = 79/388 (20%)
Query: 95 GGGPGGASG-------------GLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSK 141
GGGP G G DS RPP P ST P SG P
Sbjct: 94 GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP 153
Query: 142 KAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPS-PRGGNLPLQRLTRGS 200
G + PE + + ++PP +P + D PP PS PR P+Q
Sbjct: 154 SPGHRSGPPEPQRN--RMPPPRP------DVGSKPDSIPPPVPSTPR----PIQSSPHNR 201
Query: 201 RVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGP---TPPAGADSDSEES 257
P Q P RG GG + PL P PP
Sbjct: 202 GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP-------- 253
Query: 258 EAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTK 317
P P A + + PPP P A+PP + +PS TP
Sbjct: 254 ---------PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS----TPRP 300
Query: 318 TTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPA 377
+ + PPP P PP P S + D RLP + + STP P
Sbjct: 301 SASSQAPPPPP------PPSRPGPPPLPPSSSGNDETPRLPQ--RNLSLSSSTPPLPSPG 352
Query: 378 RERETPPPP---PPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGER--------ELPN 426
R PPPP PPPP + P GR S PLPP G +LP+
Sbjct: 353 RSGPLPPPPSERPPPPVRD-----PPGR----SGPLPPPPPVSRNGSTSRALPATPQLPS 403
Query: 427 SHSMICPKAAGAPAAPP-APAALLPGPP 453
+ P++ P PP P+A P PP
Sbjct: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPP 431
Score = 79.7 bits (195), Expect = 1e-14
Identities = 103/390 (26%), Positives = 134/390 (34%), Gaps = 78/390 (20%)
Query: 221 GDVFRGGGRSG-GGL--AGPPL-----------GGGGPT--PPAGADSDSEESEAIYEEM 264
G F GGG G GGL AG P GG P PP G + ++
Sbjct: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPG 148
Query: 265 KYPLPEEAGEGRANGPP-PLTATSPP------QQPHALPPHAHR--RPASALPSRRD--- 312
++P+P G +GPP P PP +P ++PP RP + P R
Sbjct: 149 RFPVPSP---GHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPP 205
Query: 313 --GTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGST 370
G P + +P PPPFP + G G R L S +
Sbjct: 206 VPGGPRQPSPGPTPPPFPG---------------NRGTALGGGSIRQSPLSSSSPFSNRP 250
Query: 371 PAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSM 430
P P P+R + PPPPPPP N PS R P PPQ + P P++ S
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGN----RPSIH-REAVPPPPPQNNKPPVPSTPRPSASSQ 305
Query: 431 ICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEK 490
P P PP+ P PP T ++ S P P G P
Sbjct: 306 APP-----PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 491 EISVLHGMLCTSSRPPVPGKTSP-HGGAM---------GAAAGVLHHRGCLASPHSLPDP 540
S RPP P + P G + G+ + L L S + P
Sbjct: 361 ----------PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP 410
Query: 541 TVGPLTPLWTYPATAAGLKRPPAYESLKAG 570
GP PL +A PP S++ G
Sbjct: 411 RSGPRPPLPPDRPSAGAPPPPPPSTSIRNG 440
Score = 46.2 bits (108), Expect = 1e-04
Identities = 98/423 (23%), Positives = 140/423 (33%), Gaps = 108/423 (25%)
Query: 21 KRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSAMAP 80
+ +S+K +P G PG R R + + + + P P S P
Sbjct: 134 RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 81 RSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETP-- 138
S H+ GS V GGP S G T P P + + +G GS ++P
Sbjct: 194 IQSSPHNRGS-PPVPGGPRQPSPGPT-----------PPPFPGNRGTALGGGSIRQSPLS 241
Query: 139 --------------PSKKAGSQKPTPEGRESSRK------VPPQKPRRS----PNTQLSV 174
PS+ + P P +R VPP P+ + P+T
Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301
Query: 175 SFDESCPPGPSP-RGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGG 233
+ ++ PP P P R G PL + G+ D + + + GRSG
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGN----DETPRLPQRNLSLSSSTPPLPSPGRSGPL 357
Query: 234 LAGP----------PLGGGGPTPPAGADS-DSEESEAIYEEMKYPLPEEAGEGRANGPPP 282
P P G GP PP S + S A+ + P R+ PP
Sbjct: 358 PPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP 417
Query: 283 LTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCE--------------IPPPFP 328
L PP +P A P P S R+G + +PCE +PPP P
Sbjct: 418 L----PPDRPSAGAPP----PPPPSTSIRNGF--QDSPCEDEWESRFYFHPISDLPPPEP 467
Query: 329 NLLQHR--PPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPP 386
+ + P LA +++S S RER PP P
Sbjct: 468 YVQTTKSYPSKLARNESRSGSNR----------------------------RERGAPPLP 499
Query: 387 PPP 389
P P
Sbjct: 500 PIP 502
Score = 32.7 bits (73), Expect = 1.4
Identities = 27/92 (29%), Positives = 33/92 (35%), Gaps = 22/92 (23%)
Query: 743 TPRPCSQPRDALSQPHPALPLPLPLPPQPARERDGKLLEVIERKRCVCKEIKARHRPDRG 802
TPRP + + P P+ P P PLPP + + L P R
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL------------------PQRN 338
Query: 803 LCKQESMPILPSWRRG----PEPRKSGTPPCR 830
L S P LPS R P P + PP R
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 84.7 bits (208), Expect = 3e-16
Identities = 104/388 (26%), Positives = 130/388 (33%), Gaps = 79/388 (20%)
Query: 95 GGGPGGASG-------------GLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSK 141
GGGP G G DS RPP P ST P SG P
Sbjct: 94 GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP 153
Query: 142 KAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPS-PRGGNLPLQRLTRGS 200
G + PE + + ++PP +P + D PP PS PR P+Q
Sbjct: 154 SPGHRSGPPEPQRN--RMPPPRP------DVGSKPDSIPPPVPSTPR----PIQSSPHNR 201
Query: 201 RVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGP---TPPAGADSDSEES 257
P Q P RG GG + PL P PP
Sbjct: 202 GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP-------- 253
Query: 258 EAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTK 317
P P A + + PPP P A+PP + +PS TP
Sbjct: 254 ---------PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS----TPRP 300
Query: 318 TTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPA 377
+ + PPP P PP P S + D RLP + + STP P
Sbjct: 301 SASSQAPPPPP------PPSRPGPPPLPPSSSGNDETPRLPQ--RNLSLSSSTPPLPSPG 352
Query: 378 RERETPPPP---PPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGER--------ELPN 426
R PPPP PPPP + P GR S PLPP G +LP+
Sbjct: 353 RSGPLPPPPSERPPPPVRD-----PPGR----SGPLPPPPPVSRNGSTSRALPATPQLPS 403
Query: 427 SHSMICPKAAGAPAAPP-APAALLPGPP 453
+ P++ P PP P+A P PP
Sbjct: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPP 431
Score = 79.7 bits (195), Expect = 1e-14
Identities = 103/390 (26%), Positives = 134/390 (34%), Gaps = 78/390 (20%)
Query: 221 GDVFRGGGRSG-GGL--AGPPL-----------GGGGPT--PPAGADSDSEESEAIYEEM 264
G F GGG G GGL AG P GG P PP G + ++
Sbjct: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPG 148
Query: 265 KYPLPEEAGEGRANGPP-PLTATSPP------QQPHALPPHAHR--RPASALPSRRD--- 312
++P+P G +GPP P PP +P ++PP RP + P R
Sbjct: 149 RFPVPSP---GHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPP 205
Query: 313 --GTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGST 370
G P + +P PPPFP + G G R L S +
Sbjct: 206 VPGGPRQPSPGPTPPPFPG---------------NRGTALGGGSIRQSPLSSSSPFSNRP 250
Query: 371 PAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSM 430
P P P+R + PPPPPPP N PS R P PPQ + P P++ S
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGN----RPSIH-REAVPPPPPQNNKPPVPSTPRPSASSQ 305
Query: 431 ICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEK 490
P P PP+ P PP T ++ S P P G P
Sbjct: 306 APP-----PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 491 EISVLHGMLCTSSRPPVPGKTSP-HGGAM---------GAAAGVLHHRGCLASPHSLPDP 540
S RPP P + P G + G+ + L L S + P
Sbjct: 361 ----------PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP 410
Query: 541 TVGPLTPLWTYPATAAGLKRPPAYESLKAG 570
GP PL +A PP S++ G
Sbjct: 411 RSGPRPPLPPDRPSAGAPPPPPPSTSIRNG 440
Score = 46.2 bits (108), Expect = 1e-04
Identities = 98/423 (23%), Positives = 140/423 (33%), Gaps = 108/423 (25%)
Query: 21 KRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSAMAP 80
+ +S+K +P G PG R R + + + + P P S P
Sbjct: 134 RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 81 RSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETP-- 138
S H+ GS V GGP S G T P P + + +G GS ++P
Sbjct: 194 IQSSPHNRGS-PPVPGGPRQPSPGPT-----------PPPFPGNRGTALGGGSIRQSPLS 241
Query: 139 --------------PSKKAGSQKPTPEGRESSRK------VPPQKPRRS----PNTQLSV 174
PS+ + P P +R VPP P+ + P+T
Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301
Query: 175 SFDESCPPGPSP-RGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGG 233
+ ++ PP P P R G PL + G+ D + + + GRSG
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGN----DETPRLPQRNLSLSSSTPPLPSPGRSGPL 357
Query: 234 LAGP----------PLGGGGPTPPAGADS-DSEESEAIYEEMKYPLPEEAGEGRANGPPP 282
P P G GP PP S + S A+ + P R+ PP
Sbjct: 358 PPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP 417
Query: 283 LTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCE--------------IPPPFP 328
L PP +P A P P S R+G + +PCE +PPP P
Sbjct: 418 L----PPDRPSAGAPP----PPPPSTSIRNGF--QDSPCEDEWESRFYFHPISDLPPPEP 467
Query: 329 NLLQHR--PPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPP 386
+ + P LA +++S S RER PP P
Sbjct: 468 YVQTTKSYPSKLARNESRSGSNR----------------------------RERGAPPLP 499
Query: 387 PPP 389
P P
Sbjct: 500 PIP 502
Score = 32.7 bits (73), Expect = 1.4
Identities = 27/92 (29%), Positives = 33/92 (35%), Gaps = 22/92 (23%)
Query: 743 TPRPCSQPRDALSQPHPALPLPLPLPPQPARERDGKLLEVIERKRCVCKEIKARHRPDRG 802
TPRP + + P P+ P P PLPP + + L P R
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL------------------PQRN 338
Query: 803 LCKQESMPILPSWRRG----PEPRKSGTPPCR 830
L S P LPS R P P + PP R
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 81.6 bits (200), Expect = 3e-15
Identities = 98/341 (28%), Positives = 119/341 (34%), Gaps = 69/341 (20%)
Query: 136 ETPPSKKAGS-QKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQ 194
E PS AG+ Q P+P+G + PP + P GP P+GGN P
Sbjct: 26 EESPSLIAGNPQGPSPQGGNKPQGPPPPPGK---------------PQGPPPQGGNKP-- 68
Query: 195 RLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGG----GPTPPAGA 250
G P G + P GD R G GPP GG GP PP G
Sbjct: 69 --------QGPPPPGKPQGP---PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 117
Query: 251 DSDSEESEAIYEEMKYPLPEEAGEGRANGPPPL-----TATSPPQQPHALPPHAHRRPAS 305
+ P G+ GPPP + SPP +P PP +P
Sbjct: 118 PQGPPPQGGNRPQGPPP------PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 171
Query: 306 ALP--SRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHS 363
P + G P + PP P Q PP KS S G + P
Sbjct: 172 PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPP----QGDKSRSSQSPPGKPQGPPPQGG 227
Query: 364 KEPAGSTPAPQVP-------ARERETPPPPPPP--PAANLLLLGPSGRARSHSTPLPPQG 414
+P G P P P + + PPPP P P A G S + S P PQG
Sbjct: 228 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQ----GGSKSQSARSPPGKPQG 283
Query: 415 SGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLP-GPPK 454
Q G N+ P A G P P AP A P GPP+
Sbjct: 284 PPQQEG-----NNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 319
Score = 80.5 bits (197), Expect = 6e-15
Identities = 93/342 (27%), Positives = 118/342 (34%), Gaps = 62/342 (18%)
Query: 105 LTEDSSTRRPPAKPRRHPSTKLSMVGP----GSGAETPPSKKAGSQKPTPEGRESSRKVP 160
L ED S P+ +P GP G+ + PP Q P P+G + P
Sbjct: 19 LNEDVSQEESPSLIAGNPQ------GPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP 72
Query: 161 PQKPRRSPNTQLSVSFDESCPP----GPSPRGGNLPL-----------QRLTRGSRVAGD 205
P + P Q S PP GP P+GGN P G+R G
Sbjct: 73 PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP 132
Query: 206 PDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGG----GPTPPAGADSDSEESEAIY 261
P G + P GD R G GPP GG GP PP G
Sbjct: 133 PPPGKPQGP---PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG-- 187
Query: 262 EEMKYPLPEEAGEGRANGPPP-----LTATSPPQQPHALPPHAHRRPASALPSRRDGTPT 316
++ + P P G+ GPPP ++ SPP +P PP +P G P
Sbjct: 188 KKPQGPPP----PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQP--------QGPPP 235
Query: 317 KTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVP 376
+ PPP PP PQ P G S+ ++ P G P P
Sbjct: 236 PPGKPQGPPPQGGNKPQGPPPPGKPQG-----PPAQGGSKSQ---SARSPPGKPQGP--P 285
Query: 377 ARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQP 418
+E P PPPP N + P PPQG G+P
Sbjct: 286 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG-GRP 326
Score = 62.8 bits (151), Expect = 1e-09
Identities = 62/223 (27%), Positives = 79/223 (35%), Gaps = 38/223 (17%)
Query: 96 GGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRES 155
G P G + S R PP KP+ P G+ + PP Q P P+G +
Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQG------GNQPQGPPPPPGKPQGPPPQGGKK 189
Query: 156 SRKVPPQKPRRSPNTQLSVSFDESCPPG----PSPRGGNLPLQRLTRGSRVAGDPDVGAQ 211
+ PP + P Q S PPG P P+GGN P + G P G
Sbjct: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-- 247
Query: 212 EEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEE 271
G GPP G PPA S S+ + + + + P P++
Sbjct: 248 -------------------GNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGP-PQQ 287
Query: 272 AGEGRANGPPPLTATSPPQQPHA----LPPHAHRRPASALPSR 310
G PPP A PQQP A P R P PSR
Sbjct: 288 EGNNPQGPPPP--AGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328
Score = 58.2 bits (139), Expect = 3e-08
Identities = 68/262 (25%), Positives = 84/262 (32%), Gaps = 66/262 (25%)
Query: 269 PEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFP 328
P G + GPPP PP +P PP +P P + P P P
Sbjct: 39 PSPQGGNKPQGPPP-----PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
Query: 329 NLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPP--- 385
PP Q + PG +P G P PQ R + PPP
Sbjct: 94 PGKPQGPPPQGGNQPQGPPPPPG-------------KPQG--PPPQGGNRPQGPPPPGKP 138
Query: 386 --PPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPP 443
PPP + P G+ + PPQG QP+G P P+ P PP
Sbjct: 139 QGPPPQGDKSRSPRSPPGKPQGP----PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP 194
Query: 444 APAALLPGPPK-DKAVSYTMVYSAVKVTTHSVLPAG-----PPLGAGEPKTEKEISVLHG 497
P PP+ DK+ S S P G PP G +P+
Sbjct: 195 PPGKPQGPPPQGDKSRS-------------SQSPPGKPQGPPPQGGNQPQ---------- 231
Query: 498 MLCTSSRPPVPGKTS---PHGG 516
PP PGK P GG
Sbjct: 232 -----GPPPPPGKPQGPPPQGG 248
Score = 32.0 bits (71), Expect = 2.5
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 14/80 (17%)
Query: 96 GGPGG--ASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGS-QKP--TP 150
G P G A GG ++ S R PP KP+ P + G+ + PP G+ Q+P P
Sbjct: 258 GKPQGPPAQGG-SKSQSARSPPGKPQGPPQQE------GNNPQGPPPPAGGNPQQPQAPP 310
Query: 151 EGRESSRKVPPQ--KPRRSP 168
G+ PPQ +P R P
Sbjct: 311 AGQPQGPPRPPQGGRPSRPP 330
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 72.8 bits (177), Expect = 1e-12
Identities = 94/342 (27%), Positives = 117/342 (34%), Gaps = 74/342 (21%)
Query: 98 PGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETP--------PSKKAGSQKP- 148
P G+SGG + +P + KL VG G+E PS +A + +P
Sbjct: 67 PKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRAAAPRPP 126
Query: 149 --TPEGR-----ESSRKVPPQKPRRS---------PNTQLSVSFDESC---PPGPSPRGG 189
GR +SSR P+ PR PNT S S PP P R
Sbjct: 127 VSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRA 186
Query: 190 NLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAG 249
N P L S A P Y G R G GPP PP+
Sbjct: 187 NAPPTPLPMHSSKA----------PAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSP 236
Query: 250 ADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPS 309
+ + S G++ PPP PP P+ P A LP
Sbjct: 237 VNIRTGPS-----------------GQSLAPPPPPYRQPPGVPNG-PSSPTNESAPELPQ 278
Query: 310 RRDG----TPTKTTPCEIPPPF---PNLLQHRPPLLAF-PQAKSASRTPGDGVSRL---- 357
R + TP PPP P+LL +RPP A P ++ A+ P V R
Sbjct: 279 RHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARD 338
Query: 358 ------PVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAAN 393
P H EP P P+R PPPPPPPP N
Sbjct: 339 APPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRN 380
Score = 69.3 bits (168), Expect = 1e-11
Identities = 83/316 (26%), Positives = 120/316 (37%), Gaps = 51/316 (16%)
Query: 160 PPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEM 219
PP ++ Q +S DE RG LQ + +G+++ ++ + P+ +
Sbjct: 15 PPPTFHQANTEQPKLSRDEQ-------RGRGALLQDICKGTKLKKVTNINDRSAPILEKP 67
Query: 220 VGDVFRGGGRSGGGLAGPPLGG---GGPTP--PAGADSDSEESEAIYEEMKYPL------ 268
G GG GG A P GG GG P GA D E+ A ++ P
Sbjct: 68 KGS---SGGYGSGGAALQPKGGLFQGGVLKLRPVGA-KDGSENLAGKPALQIPSSRAAAP 123
Query: 269 --PEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPP 326
P A GR + S P+ P P P + P+ T K + PPP
Sbjct: 124 RPPVSAASGRPQDDTDSSRASLPELPRMQRPSL---PDLSRPNTTSSTGMKHSSSAPPPP 180
Query: 327 FPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQV-PARERETPPP 385
P + PP P +S+ P + ++P TP ++ P RE PP
Sbjct: 181 PPGRRANAPPT---PLPMHSSKAPA---------YNREKPLPPTPGQRLHPGREGPPAPP 228
Query: 386 P-PPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGER--------ELPNSHSMICPKAA 436
P PPP+ + GPSG++ + P Q G P G ELP H+ + K
Sbjct: 229 PVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTP 288
Query: 437 G--APAAPPAPAALLP 450
G APP P + P
Sbjct: 289 GPVRGLAPPPPTSASP 304
Score = 38.1 bits (87), Expect = 0.034
Identities = 62/247 (25%), Positives = 80/247 (32%), Gaps = 43/247 (17%)
Query: 101 ASGGLTEDSSTRRPPAKPRRH--PSTKLSMVGPGSGAETPPSKKAGSQKPTP-----EGR 153
+S G+ SS PP RR P T L M ++ P + PTP GR
Sbjct: 166 SSTGMKHSSSAPPPPPPGRRANAPPTPLPM----HSSKAPAYNREKPLPPTPGQRLHPGR 221
Query: 154 ESSRKVPPQKPRRSP-NTQLSVSFDESCPPGPS-------PRGGNLPLQRLTRGSRVAGD 205
E PP KP SP N + S PP P P G + P
Sbjct: 222 EGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESA-------- 273
Query: 206 PDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPA------GADSDSEESEA 259
P++ + ++ + G V RG A P L P PPA GA
Sbjct: 274 PELPQRHNSLHRKTPGPV-RGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVI 332
Query: 260 IYEEMKYPLP---------EEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSR 310
P P E G+ PP T PP P + HR + + S
Sbjct: 333 RNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSF 392
Query: 311 RDGTPTK 317
D +K
Sbjct: 393 LDDFESK 399
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 71.2 bits (173), Expect = 4e-12
Identities = 80/309 (25%), Positives = 107/309 (34%), Gaps = 60/309 (19%)
Query: 94 VGGGPGGASG-GLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEG 152
+ G P G G + T PP KP P G+ ++ PP + + P P+G
Sbjct: 32 ISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQG------GNQSQGPPPRPGKPEGPPPQG 85
Query: 153 RESSRKVPPQ--KPRRSP----NTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDP 206
S+ PP+ KP P N P GP P+GGN R + G P
Sbjct: 86 GNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 145
Query: 207 DVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGG----GPTPPAGADSDSEESEAIYE 262
G G+ +G G GPP GG GP P G
Sbjct: 146 PQG-----------GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPG------------- 181
Query: 263 EMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPAS--ALPSRRDGTPTK-TT 319
K P G ++ GPPP P +P PP + P + +G P++
Sbjct: 182 --KPEGPPPQGGNQSQGPPP-----RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGN 234
Query: 320 PCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARE 379
+ PPP P Q PP + R P G + P P G+ P P
Sbjct: 235 KPQGPPPHPGKPQGPPP----QEGNKPQRPPPPGRPQGP-----PPPGGNPQQPLPPPAG 285
Query: 380 RETPPPPPP 388
+ PPPPP
Sbjct: 286 KPQGPPPPP 294
Score = 62.0 bits (149), Expect = 2e-09
Identities = 77/287 (26%), Positives = 97/287 (33%), Gaps = 65/287 (22%)
Query: 181 PPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLG 240
P G P+GGN P + + G P G G+ +G G GPP
Sbjct: 36 PEGRRPQGGNQPQRTPPPPGKPEGRPPQG-----------GNQSQGPPPRPGKPEGPPPQ 84
Query: 241 GG----GPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALP 296
GG GP P G P + G ++ GPPP P +P P
Sbjct: 85 GGNQSQGPPPRPGKPEGQ--------------PPQGGN-QSQGPPPR-----PGKPEGPP 124
Query: 297 PHAHRRPASALPSRRDGTPTKTTP-----CEIPPPFPNLLQHRPPLLAFPQAKSASRTPG 351
P + S P R G P P + PPP P + PP Q + S+ P
Sbjct: 125 PQGGNQ--SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP-----QGGNQSQGPP 177
Query: 352 DGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPP-----PPPAANLLLLGPSGRARSH 406
H +P G P PQ + + PPP P PPP GP R
Sbjct: 178 P---------HPGKPEG--PPPQ-GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 225
Query: 407 STPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPP 453
P P QG +P+G P P+ P PP P PP
Sbjct: 226 EGP-PSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPP 271
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 70.9 bits (172), Expect = 5e-12
Identities = 166/659 (25%), Positives = 214/659 (32%), Gaps = 112/659 (16%)
Query: 64 PASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPS 123
P S T HP + A SL+ HS + S P + S + PPA P
Sbjct: 479 PLSSPLTIHPLQ---ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL 535
Query: 124 TKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVP-----PQKPRRSPNTQLSVSFDE 178
L + P PP + A + TP P P P +P + S
Sbjct: 536 ENLPSLAP------PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI-A 588
Query: 179 SCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPP 238
+ PP P + PLQ L P + P ++ LA PP
Sbjct: 589 TPPPQAPPALASPPLQGLP-------SPPLSPLATPP------------PQAPPXLALPP 629
Query: 239 LGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRAN------GPPPLTATSPPQQP 292
L P+PPA + P P+ + PPP SPP Q
Sbjct: 630 LQAP-PSPPASPP---------LSPLATPSPQAPNALAVHLLQAPFSPPP----SPPVQA 675
Query: 293 HALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGD 352
PP + SA P + P ++PP P P PQA P
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
Query: 353 GVSRLPVLCHSKEPAGSTPAPQVP----ARERETPPPPP----------PPPAANLLLLG 398
V P P+ +TP P+VP A + PP PP PPP A L
Sbjct: 736 QVPPSPPASPPMSPS-ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 399 PSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAA-LLPGPPKDKA 457
P +A LP + P P++ + P A P APP AA LL PP A
Sbjct: 795 PPLQA------LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 848
Query: 458 VSYTMVYSAVKVTTHSVLPAGPPL------GAGEPKTEKEISVL-------HGMLCTSSR 504
+GP L G P + S L H TS+
Sbjct: 849 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908
Query: 505 PPVPGKTS-PHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPA 563
+ G S P GGA + C + S GP PL A A L PPA
Sbjct: 909 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-----GPAPPLAFRGAPGAPLPWPPA 963
Query: 564 YESLKAGGVL----NKGCGVGAPSPMVKIQLQEQGTDGGAFASISCAHVIASAGTPEEEE 619
A G+ +G P+P GT GG A A A A + ++
Sbjct: 964 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA----AGAGAGASSRSPKQ 1019
Query: 620 EEVGAATFGAGWALQRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSG 678
+G G ALQ V+ L +GA GS GPG E G G +G
Sbjct: 1020 ARLGELPLG---ALQASVVQHLLSRTLLLAAAEGAA--GGSGGGPGGAE----GGGVTG 1069
Score = 56.6 bits (135), Expect = 9e-08
Identities = 132/534 (24%), Positives = 177/534 (33%), Gaps = 116/534 (21%)
Query: 70 TPHPCRSAMAPRSLS---CHSVGSMDSVG--------GGPGGA-------------SGGL 105
TP P S P ++ +G+ +VG GG GGA S G
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 106 TEDSSTRRPPAKPR--RHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSR-----K 158
+ + RPPA R R P K + GP S P + +G+ +P P G++ R
Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSS----PGRASGTTRPGPLGQKGLRISAEET 141
Query: 159 VPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIE 218
V K +P + GP+P P + R SR AG +VG
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTP---GTPSPAMARRSRAAGT-EVGLPR------ 191
Query: 219 MVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRAN 278
P P PP S S + + + P A R +
Sbjct: 192 -------------------PAPSARPRPPTEGPRKSVSSASEHSTTE---PSPAARRRPS 229
Query: 279 GPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLL 338
L + + P + PA + PS R GTP P P P LQ P
Sbjct: 230 AGGGLQRPASRSLSSSATPLSS--PARSGPSAR-GTPR--APAHPSQPKPKGLQALRPPQ 284
Query: 339 AFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPP----PPPPPAANL 394
P K A+ G +S P+ S P+G+ P P TP P P PP A L
Sbjct: 285 VTPPRKDAAPALGP-LSSSPLATPS--PSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 395 LLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLP---G 451
L PS A LP + P + P SM P P+ P +P
Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPP---SQAP--PSMTTPPMQAPPSLQTIPPIQVPHSLT 396
Query: 452 PPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKT 511
P +A + S+++ TT G P + H L S R T
Sbjct: 397 SPSLQAPPSPLALSSLQATT----------SLGSP----TLQATHSFLTMSPRQTQASLT 442
Query: 512 SPHGGAMGAAAGVLHHRGCLASPHSLP---------DPTVGPL-TPLWTYPATA 555
SP A L +P SLP P V PL +PL +P A
Sbjct: 443 SP-----SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491
Score = 31.6 bits (70), Expect = 3.2
Identities = 94/416 (22%), Positives = 129/416 (31%), Gaps = 86/416 (20%)
Query: 363 SKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGER 422
++ PA P P PPPP PAA L +LG +G PL + G G
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAA-LRVLGAAGAV--GRKPLAERAGG--IGGA 68
Query: 423 ELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLG 482
+P S AP A P +A T S PA P
Sbjct: 69 TIPES----------APRAGPTRSA----------------------GTSSRNPASRPPA 96
Query: 483 AGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAA-AGVLHHRGCLASPHSLPDPT 541
+G G ++ PG S G A G G L +G S + T
Sbjct: 97 SG-----------RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS----AEET 141
Query: 542 V--GPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMVKIQLQEQGTDGGA 599
V G T A +AG +R G G PSP + + + GT+ G
Sbjct: 142 VARGKATEAPKRSALSAGARRD------------TSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 600 FASISCAHVIASAGTPEEEEEEVG--AATFGAGWALQRKVLYGGRKAKELDKVEDGARAW 657
A P + + T + A +R GG + + A
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 658 NGSAEGPGKVEREDRGPGTSGIPVRSQGAEGLLARIHHGDRGGSRTALPIPCQTFPACHR 717
+ A R P P + +G + L R + AL P + P
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQP-KPKGLQALRPPQVTPPRKDAAPALG-PLSSSPLA-- 305
Query: 718 NGDFTGGYRLGRSASTSGVRQVVLHTPRPCSQPRDALSQPHPALPLPLPL-PPQPA 772
+ S SG + + P + P A P P L PLPL PP P+
Sbjct: 306 ------------TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 70.9 bits (172), Expect = 5e-12
Identities = 173/718 (24%), Positives = 229/718 (31%), Gaps = 151/718 (21%)
Query: 19 EAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSAM 78
+A + + AG+ +G PG +A RRS G + P
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMA--RRSRAAGTEVGLPRPAPSARPRPPTE 194
Query: 79 APR----SLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVG-PGS 133
PR S S HS A GGL +RP ++ +T LS G
Sbjct: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGL------QRPASRSLSSSATPLSSPARSGP 248
Query: 134 GAETPPSKKAGSQKPTPEGRESSRK---VPPQKPRRSPNTQLSVSF----DESCPPGPS- 185
A P A +P P+G ++ R PP+K LS S S PP PS
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308
Query: 186 -PRGGNLPLQRLTRGSRVA---GDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGG 241
P LP T S+ G P + A + + + ++ LA PPL
Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 368
Query: 242 GGPTPPAG--------------------------ADSDSEESEAIYEEMKYPLPEEAGEG 275
P+PPA + S +A + P +
Sbjct: 369 P-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427
Query: 276 RANGPPPLTA----------TSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPP 325
+ PP L A SPP P A PP P +A P + PP
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ----------LAKPP 477
Query: 326 PFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPP 385
P PP LA P ++ P + P +P+ +P TPPP
Sbjct: 478 P------QAPPALATPPLQALPSPPASFPGQAPF----------SPSASLPMSPLATPPP 521
Query: 386 PPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAP 445
PP A LL P P PP S + R P P + + P
Sbjct: 522 QAPPVLAAPLLQVP---------PSPP-ASPTLQAPRRPPT------PGPDTSVSGPRLT 565
Query: 446 AALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRP 505
AL PGPP + S + S GP L H TS+
Sbjct: 566 LALAPGPPPPPSRSPSSTLS------------GPDLAG------------HSSSATSTPE 601
Query: 506 PVPGKTS-PHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAY 564
+ G S P GGA + C + S GP PL A A L PPA
Sbjct: 602 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-----GPAPPLAFRGAPGAPLPWPPAT 656
Query: 565 ESLKAGGVL----NKGCGVGAPSPMVKIQLQEQGTDGGAFASISCAHVIASAGTPEEEEE 620
A G+ +G P+P GT GG A A A A + ++
Sbjct: 657 GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA----AGAGAGASSRSPKQA 712
Query: 621 EVGAATFGAGWALQRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSG 678
+G G ALQ V+ L +GA GS GPG E G G +G
Sbjct: 713 RLGELPLG---ALQASVVQHLLSRTLLLAAAEGAA--GGSGGGPGGAE----GGGVTG 761
Score = 66.6 bits (161), Expect = 9e-11
Identities = 143/557 (25%), Positives = 187/557 (33%), Gaps = 93/557 (16%)
Query: 70 TPHPCRSAMAPRSLS---CHSVGSMDSVGGGP-----GGASGGLTEDSS-------TRRP 114
TP P S P ++ +G+ +VG P GG G +S+ T RP
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85
Query: 115 PAKPR--RHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSR-----KVPPQKPRRS 167
PA R R P K + GP S P + +G+ +P P G++ R V K +
Sbjct: 86 PASGRGERAPPAKNTSPGPVSS----PGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141
Query: 168 PNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGD------PDVGAQEEPVYIEMVG 221
P + GP+P P + R SR AG P A+ P
Sbjct: 142 PKRSALSAGARRDTSGPTP---GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198
Query: 222 DVFRGGGRS----GGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEG-R 276
V S P GGG PA S + PL A G
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT---------PLSSPARSGPS 249
Query: 277 ANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPT--------KTTPCEIPPPFP 328
A G P A + P QP A RP P R+D P TP PP P
Sbjct: 250 ARGTP--RAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 329 NLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAG-----STPAPQVPARERETP 383
+ L + P + T G L HS P+ +TP PQ P P
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQA-THSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 384 -PPPPPPPAANLL--LLGPSGRARSH------STPLPPQGSGQPRGERELPNSHSMICPK 434
PP PPA+ L L PS +A + P P S P P + + P
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS-PPVQAPFSPPASPPVSPS 424
Query: 435 AAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISV 494
A APP+ AA P S M SA A PPL +P + ++
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484
Query: 495 LHGMLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPL--TPLWTYP 552
+ PP+ SP G A SP + P P P+ PL P
Sbjct: 485 --------ATPPLQALPSPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535
Query: 553 ATAAGLKRPPAYESLKA 569
+ PPA +L+A
Sbjct: 536 PS------PPASPTLQA 546
Score = 56.2 bits (134), Expect = 1e-07
Identities = 112/468 (23%), Positives = 160/468 (34%), Gaps = 71/468 (15%)
Query: 132 GSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNL 191
G+ A TP ++ G P P G S R PP P L V G + G
Sbjct: 11 GAAARTPAARAPGLLTPRPPG--SPRPPPPVTP-----AALRVL-------GAAGAVGRK 56
Query: 192 PLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTP---PA 248
PL G A P+ + P SG G PP P P P
Sbjct: 57 PLAERAGGIGGATIPESAPRAGPTRTSRPP-------ASGRGERAPPAKNTSPGPVSSPG 109
Query: 249 GADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRRPASAL 307
A + + ++ E G+A P +A S ++ + P PA A
Sbjct: 110 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 169
Query: 308 PSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPA 367
SR GT +P P P+ + RPP P+ +S + P
Sbjct: 170 RSRAAGTEVG-----LPRPAPSA-RPRPPTEG-PRKSVSSASEHSTTEPSPAARRRPSAG 222
Query: 368 GSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGEREL--- 424
G P +R + P PA + GPS R + P Q +P+G + L
Sbjct: 223 GGLQRPA--SRSLSSSATPLSSPARS----GPSARGTPRAPAHPSQP--KPKGLQALRPP 274
Query: 425 --------------PNSHSMIC---PKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAV 467
P S S + P A +P+APP+ L P + + T + S
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 468 KVTTHSVLPAGP--PLGAGEPKTEKEISV--LHGMLCTSSRPPVPGKTSPHGGAMGAAAG 523
THS LP+ P PL P+ +++ L + PP+ +P A A A
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394
Query: 524 VLHHRGCLASPHSLP--DPTVGPLTPLWTYPATAAGLKRPPAYESLKA 569
L L +P S P P P +P + P + + A SL A
Sbjct: 395 HL-----LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 437
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 69.7 bits (169), Expect = 1e-11
Identities = 119/500 (23%), Positives = 170/500 (34%), Gaps = 96/500 (19%)
Query: 132 GSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPR------------RSPNTQLSVSFDES 179
G+ A TP ++ G P P G S R PP P R P + + +
Sbjct: 11 GAAARTPAARAPGLLTPRPPG--SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 180 CPPGPSPRGGNLPLQRLTRGSR-VAGDPDV---GAQEEPVYIEMVGDVFRGGGRSGGGLA 235
P +PR G P + SR A P G + P G V G SG
Sbjct: 69 TIPESAPRAG--PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 236 GP--------------------------PLGGG------GPTPPAGADSDSEESEAIYEE 263
GP L G GPTP + + + S A E
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 264 MKYPLPEEAGEGR--ANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPC 321
+ P P + R GP +++ P A RRP++ +R P +
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR---PASRSLS 243
Query: 322 EIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERE 381
P + P + P A+ R P P + P PQV ++
Sbjct: 244 SSATPLSS------PARSGPSARGTPRAPAHPSQPKPKGLQALRP------PQVTPPRKD 291
Query: 382 TPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAA 441
P P ++ L PS +S + P P P+S S+ C A P A
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLP----------ATPHSSSLTCQLATPLPLA 341
Query: 442 PPAPAA-----LLPGPP-KDKAVSYTMVYSAVKVTTHSVLPAGP--PLGAGEPKTEKEIS 493
PP+P+A LP PP + + T + S THS LP+ P PL P+ ++
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 494 V--LHGMLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLP--DPTVGPLTPLW 549
+ L + PP+ +P A A A L L +P S P P P +P
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-----LQAPFSPPPSPPVQAPFSPPA 456
Query: 550 TYPATAAGLKRPPAYESLKA 569
+ P + + A SL A
Sbjct: 457 SPPVSPSATPPSQAPPSLAA 476
Score = 68.2 bits (165), Expect = 3e-11
Identities = 180/762 (23%), Positives = 239/762 (31%), Gaps = 156/762 (20%)
Query: 13 RQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPH 72
R + AK +S V+ G A GP +G + S E T
Sbjct: 99 RGERAPPAKNTSPGPVSSPGRASGTTRPGP---------------LGQKGLRISAEETVA 143
Query: 73 PCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTE---------------DSSTRRPPAK 117
++ AP+ + + D+ G PG S + S+ RPP +
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 118 -PRRHPST--KLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSV 174
PR+ S+ + S P A PS G Q+P SS P P RS +
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA-TPLSSPARSGPSARGT 262
Query: 175 SFDESCPPGPSPRGGNL---------------PLQRLTRGSRVAGDPDVGAQEE------ 213
+ P P P+G L L+ P Q +
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322
Query: 214 --PVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEES------EAIYEEMK 265
P + + + + PP P+PPA S + S +A + +
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 382
Query: 266 YPL-------PEEAGEGRANGP----------PPLT--ATSPPQQPHALPPHAHRRPASA 306
P P +A A P PPL+ AT PQ P+AL H + P S
Sbjct: 383 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 442
Query: 307 LPS-----------RRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVS 355
PS +P+ T P + PP PPL P ++
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA-----APPLQVPPSPPAS--------- 488
Query: 356 RLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGS 415
P + S P P P + PPP PPA L P S P Q
Sbjct: 489 --PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA---LATPPLQALPSPPASFPGQAP 543
Query: 416 GQPRGERELPNSHSMICPKAAGAPAAPPAPAA-LLPGPPKDKAVSYTMVYSAVKVTTHSV 474
P LP S P A P APP AA LL PP A
Sbjct: 544 FSP--SASLPMS-----PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596
Query: 475 LPAGPPL------GAGEPKTEKEISVL-------HGMLCTSSRPPVPGKTS-PHGGAMGA 520
+GP L G P + S L H TS+ + G S P GGA +
Sbjct: 597 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 656
Query: 521 AAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVL----NKG 576
C + S GP PL A A L PPA A G+ +G
Sbjct: 657 PPPDAELAACHPAAWSR-----GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711
Query: 577 CGVGAPSPMVKIQLQEQGTDGGAFASISCAHVIASAGTPEEEEEEVGAATFGAGWALQRK 636
P+P GT GG A A A A + ++ +G G ALQ
Sbjct: 712 PESATPAPGALDPGPSPGTSGGKAA----AGAGAGASSRSPKQARLGELPLG---ALQAS 764
Query: 637 VLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSG 678
V+ L +GA GS GPG E G G +G
Sbjct: 765 VVQHLLSRTLLLAAAEGAA--GGSGGGPGGAE----GGGVTG 800
Score = 30.8 bits (68), Expect = 5.5
Identities = 60/234 (25%), Positives = 79/234 (33%), Gaps = 32/234 (13%)
Query: 363 SKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGER 422
++ PA P P PPPP PAA L +LG +G PL + G G
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAA-LRVLGAAGAV--GRKPLAERAGG--IGGA 68
Query: 423 ELPNSHSMICP-KAAGA----PAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPA 477
+P S P ++AG PA+ P + P K S V S + S
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA---SGTTR 125
Query: 478 GPPLGAGEPKTEKEISVLHGMLCTSSR-------------PPVPGKTSPHGGAMGAAAGV 524
PLG + E +V G + + P PG SP AAG
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 525 ---LHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNK 575
L A P PT GP + + + P A AGG L +
Sbjct: 186 EVGLPRPAPSARPR---PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 68.2 bits (165), Expect = 3e-11
Identities = 113/406 (27%), Positives = 127/406 (31%), Gaps = 49/406 (12%)
Query: 122 PSTKLSMVGPGSG-AETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESC 180
P T+ S PG G PP G PT + P Q P +
Sbjct: 862 PCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIP 921
Query: 181 PPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLG 240
PP P P G LPL L G+ + P + P + G G PPL
Sbjct: 922 PPPPLPGAGILPLPPLP-GAGIPPPPPLPGAAIPPPPPLPG---------AGIPLPPPLP 971
Query: 241 GGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAH 300
G G PP P P PPPL P P P A
Sbjct: 972 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAG 1029
Query: 301 RRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVL 360
P LP G P PPP P PP L PG G+ P L
Sbjct: 1030 IPPPPPLPGA--GIPP-------PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
Query: 361 CHSKEPAGSTPAPQVPARERETPPP------PPPPPAANLLLLGPSGRARSHSTPLPP-Q 413
AG P P +P PPP PPPPP + P + P PP
Sbjct: 1081 ----PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1136
Query: 414 GSGQPRGERELPNSHSMICPK--AAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTT 471
G+G P LP P AG P PP P A +P PP V V
Sbjct: 1137 GAGIPPPP-PLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG- 1194
Query: 472 HSVLPAGPPL-GAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGG 516
+P PPL GAG P L GM PP P P G
Sbjct: 1195 ---IPPPPPLPGAGIPPPPP----LPGM----GIPPAPAPPLPPPG 1229
Score = 65.9 bits (159), Expect = 2e-10
Identities = 99/376 (26%), Positives = 132/376 (35%), Gaps = 90/376 (23%)
Query: 231 GGGLAGPPLGG--GGPTPPAGADSDSE-----ESEAIYEEMKYPLPEEAGE-----GRAN 278
GG L PP+ G G P P GA+S + E I + + ++ + +
Sbjct: 752 GGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811
Query: 279 GPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLL 338
PP L ++ QP + PPH+ + K + C IP P PPL
Sbjct: 812 PPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNS-CNIPSP--------PPL- 861
Query: 339 AFPQAKSASRTPGDGV-----SRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAAN 393
P +S+S PG G+ LP + P ST PQ P + PPPPPP
Sbjct: 862 --PCTESSSSMPGLGMVPPPPPPLPGMTVPTLP--STAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 394 LLLLGPSGRARSHSTPLPP-QGSGQPRGERELPNSHSMICP--KAAGAPAAPPAPAALLP 450
+ P + PLPP G+G P LP + P AG P PP P A +P
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIP-PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976
Query: 451 GPPKDKAVSYTMVYSAVKVTTHSVLPAGPPL-GAGEPKTEKEISVLHGMLCTSSRPPVPG 509
PP +P PPL GAG P PP+PG
Sbjct: 977 PPPPLPGAG---------------IPPPPPLPGAGIPPP----------------PPLPG 1005
Query: 510 KTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKA 569
P + A + P LP + P PL AG+ PP
Sbjct: 1006 AGIPPPPPLPGAG--------IPPPPPLPGAGIPPPPPL-----PGAGIPPPPPL----- 1047
Query: 570 GGVLNKGCGVGAPSPM 585
G G+ P P+
Sbjct: 1048 -----PGAGIPPPPPL 1058
Score = 64.7 bits (156), Expect = 3e-10
Identities = 85/348 (24%), Positives = 104/348 (29%), Gaps = 44/348 (12%)
Query: 114 PPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLS 173
PP P L PG+G PP P P + PP P
Sbjct: 954 PPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP--------- 1004
Query: 174 VSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGG 233
PP P G +P G+ + P + P + G G
Sbjct: 1005 ---GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG---------AGI 1052
Query: 234 LAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATS---PPQ 290
PPL G G PP P P PPPL PP
Sbjct: 1053 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112
Query: 291 QPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTP 350
P A P P + +P P PPP P + PP L P
Sbjct: 1113 LPGAGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169
Query: 351 GDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPP------PPPPPAANLLLLGPSGRAR 404
G G+ P L G P P +P PPP PPPPP + G
Sbjct: 1170 GAGIPPPPPL----PGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM------GIPP 1219
Query: 405 SHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGP 452
+ + PLPP G+G P LP S + P+ + P LP P
Sbjct: 1220 APAPPLPPPGTGIPPPPL-LPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266
Score = 63.5 bits (153), Expect = 8e-10
Identities = 97/366 (26%), Positives = 117/366 (31%), Gaps = 96/366 (26%)
Query: 231 GGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQ 290
G G+ PP P P G + S AI + P P + E PPPL P
Sbjct: 872 GLGMVPPP-----PPPLPGMTVPTLPSTAIPQ----PPPLQGTEMLPPPPPPLPGAGIPP 922
Query: 291 QPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTP 350
P P A P LP G P PPP P PP L P
Sbjct: 923 PPPL--PGAGILPLPPLPGA--GIPP-------PPPLPGAAIPPPPPLPGAGIPLPPPLP 971
Query: 351 GDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPP------PPPPPAANLLLLGPSGRAR 404
G G+ P L AG P P +P PPP PPPPP + P
Sbjct: 972 GAGIPPPPPL----PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
Query: 405 SHSTPLPP-QGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMV 463
+ P PP G+G P LP AG P PP P A +P PP
Sbjct: 1028 AGIPPPPPLPGAGIPPPP-PLPG---------AGIPPPPPLPGAGIPPPPPLPGAG---- 1073
Query: 464 YSAVKVTTHSVLPAGPPL-GAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAA 522
+P PPL GAG P PP+PG P +
Sbjct: 1074 -----------IPPPPPLPGAGIPPP----------------PPLPGAGIPPPPPLPGVG 1106
Query: 523 GVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAP 582
+ P LP + P PL AG+ PP G G+ P
Sbjct: 1107 --------IPPPPPLPGAGIPPPPPL-----PGAGIPPPPPL----------PGAGIPPP 1143
Query: 583 SPMVKI 588
P+ ++
Sbjct: 1144 PPLPRV 1149
Score = 43.9 bits (102), Expect = 6e-04
Identities = 75/311 (24%), Positives = 92/311 (29%), Gaps = 55/311 (17%)
Query: 131 PGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGN 190
PG+G PP P P + PP P PP P G
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP------------GAGIPPPPPLPGAG 1062
Query: 191 LPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGA 250
+P G+ + P + P + G G PPL G G PP
Sbjct: 1063 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG---------AGIPPPPPLPGVGIPPPPPL 1113
Query: 251 DSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATS---PPQQPHALPPHAHRRPASAL 307
P P PPPL PP P A P P + +
Sbjct: 1114 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGI 1173
Query: 308 PSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPA 367
P P PPP P + PP L PG G+ PA
Sbjct: 1174 PPP---PPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGI----------PPA 1220
Query: 368 GSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTP-----LPPQ--------G 414
PAP +P PPPP P + LL P + + TP LPP G
Sbjct: 1221 ---PAPPLPPPGTGIPPPPLLPVSGPPLL--PQVGSSTLPTPQVCGFLPPPLPSGLFGLG 1275
Query: 415 SGQPRGERELP 425
Q +G R+ P
Sbjct: 1276 MNQDKGSRKQP 1286
Score = 31.6 bits (70), Expect = 3.2
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 20/84 (23%)
Query: 381 ETPPPPP----PPPAANL----LLLGPSG------------RARSHSTPLPPQGSGQPRG 420
E P PP P P A L LLGPSG +A S + LP + +PR
Sbjct: 230 EEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPRE 289
Query: 421 ERELPNSHSMICPKAAGAPAAPPA 444
++ P+ + +A PAA PA
Sbjct: 290 PQQPPSPGGLPVSEAPSLPAAQPA 313
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 68.2 bits (165), Expect = 3e-11
Identities = 133/572 (23%), Positives = 176/572 (30%), Gaps = 129/572 (22%)
Query: 82 SLSCHSVGSMDSVGGGPGGASGGLTEDSST--------------------RRPPAKPRR- 120
S + +SV G G G SGG T ++S +RPP PRR
Sbjct: 445 STASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRT 504
Query: 121 HPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESC 180
H + + P PP PE RK PQ PR + C
Sbjct: 505 HSLHQRGLAVPDGPLGLPPK---------PE-----RKQQPQLPRPPTTGGSEGAGAAPC 550
Query: 181 PPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGG-------G 233
PP P+ S V G G++ P E G G G
Sbjct: 551 PPNPA-------------NSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKG 597
Query: 234 LAGPPLGGGGPTPP---------AGADSDSEESEAIYEEMKYPLPEEAGEGRANGP---- 280
LAGPP G PP + S S ++ P P + + P
Sbjct: 598 LAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDR 657
Query: 281 --------PPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNL-- 330
P + PP +P + P A PA A P+ G + T PP P
Sbjct: 658 FVIPPHPKVPAPFSPPPSKPRSPNPAA---PALAAPAVVPGPVSTTDASPQSPPTPQTTL 714
Query: 331 --LQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAP------QVPARERET 382
LQ P + +K S P S P +K+P AP + P ++
Sbjct: 715 TPLQESPVI-----SKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNW 769
Query: 383 PPPPPPPPAANLLLLG----PSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGA 438
PPPPPP P L + P S ++P P SG P EL +S + A
Sbjct: 770 PPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSP----ELVSSPAASSSSATAL 825
Query: 439 PAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGM 498
PP P PP S + A P G G G P+ + ++
Sbjct: 826 QIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKE---PVGCSKGGGPPREDVGAPLVTPS 882
Query: 499 LCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGL 558
L R G +P P P +GP P +G
Sbjct: 883 LLQMVRLRSVG-----------------------APGGAPTPALGPSAPQKPLRRALSGR 919
Query: 559 KRP-PAYESLKAGGVLNKGCGVGAPSPMVKIQ 589
P PA S V K C + A + Q
Sbjct: 920 ASPVPAPSSGLHAAVRLKACSLAASEGLSSAQ 951
Score = 47.0 bits (110), Expect = 7e-05
Identities = 102/453 (22%), Positives = 141/453 (31%), Gaps = 61/453 (13%)
Query: 23 SSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSAMAPRS 82
SSS + AP+ +GP G R + + F + P S+ +P+P A+A +
Sbjct: 635 SSSSDPAPSDRSGPQILTPLGDRF--VIPPHPKVPAPF-SPPPSKPRSPNPAAPALAAPA 691
Query: 83 LSCHSVGSMDSVGGGPGGASGGLTE------DSSTRRPPAKPRRHPSTKLSMVGPGSGAE 136
+ V + D+ P LT S + PP P P
Sbjct: 692 VVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPP-----------PSYHPP 740
Query: 137 TPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRL 196
PP+KK P E++ + P Q P P PP P+P +L +
Sbjct: 741 PPPTKKPEVVVEAPSASETAEE-PLQDPNWPP------------PPPPAPEEQDLSMADF 787
Query: 197 TRGSR----VAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADS 252
VA G P E+V + PP G P PP +
Sbjct: 788 PPPEEAFFSVASPEPAGPSGSP---ELVSSPAASSSSATALQIQPP---GSPDPPPAPPA 841
Query: 253 DSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRD 312
+ S A K P E G + GPP +P P L + R
Sbjct: 842 PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLL---------QMVRLRSV 892
Query: 313 GTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPA 372
G P + P P +P A S P G+ L A +
Sbjct: 893 GAPGGAPTPALGPSAP----QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLS 948
Query: 373 PQVPARERETPPPPPPPPAANLLLLGPSG-RARSHSTPLPP--QGSGQPRGERELPNSHS 429
P E P PP PA+ + G R P+ P Q Q EL +
Sbjct: 949 SAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISE 1008
Query: 430 MICPKAAGAPAAPPAPAALLP--GPPKDKAVSY 460
P+A P P A P G P + SY
Sbjct: 1009 QRPPQAPKKSPKAPPPVARKPSVGVPPPASPSY 1041
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 67.8 bits (164), Expect = 4e-11
Identities = 77/333 (23%), Positives = 107/333 (32%), Gaps = 26/333 (7%)
Query: 245 TPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPA 304
T + + E + +E P+E P P T S P P P ++PA
Sbjct: 251 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310
Query: 305 SALPSRRDGT----PTKTTPCEIPP----PFPNLLQHRPPLLAFPQAKSASRTPGDGVSR 356
P T PT TTP E P P P + P A + + P +
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 370
Query: 357 LPVLCHSKEPAGSTPAPQVPARERETP-----PPPPPPPAANLLLLGPSGRARSHSTPLP 411
P +KEP+ +TP P + P P P +A PS P
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430
Query: 412 PQGSGQPRGERELPNSHSMICPKAAGAPA-------APPAPAALLPGPPKDKAVSYTMVY 464
P+ ++ P + P PA AP P P PK+ A T
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP--TTPK 488
Query: 465 SAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGV 524
T + P P A P T +E++ T + P P T+P A
Sbjct: 489 KLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546
Query: 525 LHHRGCLASPHSLPDPTVGPLTPLWTYPATAAG 557
+P + +P P TP T P T G
Sbjct: 547 APTTPKEPAPTTPKEP--APTTPKETAPTTPKG 577
Score = 62.0 bits (149), Expect = 2e-09
Identities = 101/455 (22%), Positives = 133/455 (29%), Gaps = 56/455 (12%)
Query: 109 SSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSP 168
++T+ P P+ T P + E P+ TP+ + K P + P
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348
Query: 169 NTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGG 228
+ P P+P P T+ +P +EP
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTK------EPSPTTPKEP------APTTTKSA 396
Query: 229 RSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSP 288
+ P PT P E S +E P+E P P T P
Sbjct: 397 PTTTKEPAPTTTKSAPTTP------KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450
Query: 289 -PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA--KS 345
P P P ++PA P P TTP E P P L P P K
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506
Query: 346 ASRTPGD---GVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402
A TP + P +EPA +TP P +E P P PA P+
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT-TPKEPAPT 565
Query: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALL---PGPPKDKAVS 459
+ P P+G+ + P + PK AP P + P P K +
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTA 624
Query: 460 YTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMG 519
T T P P A P T KE P P K +P A
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTA--PTTLKE-----------PAPTTPKKPAPKELAPT 671
Query: 520 AAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPAT 554
G P S P TP T P T
Sbjct: 672 TTKG----------PTSTTSDKPAPTTPKETAPTT 696
Score = 53.9 bits (128), Expect = 6e-07
Identities = 56/234 (23%), Positives = 72/234 (30%), Gaps = 19/234 (8%)
Query: 280 PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA 339
P P T S P P P + PA P T TK P + P
Sbjct: 247 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 306
Query: 340 FPQAKSASRTPGDGVSRLPVLCHSKEPAGST--PAPQVPARERETPPPPPPPPAANLLLL 397
A + + P + P KEPA +T PAP P T P P P
Sbjct: 307 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP-------- 358
Query: 398 GPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKA 457
+ + + +TP P + P + K+A PAP P K
Sbjct: 359 -TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417
Query: 458 VSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKT 511
S T T P P A P T KE + T+ + P P T
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPA--PTTPKEPAP------TTPKEPAPTTT 463
Score = 49.7 bits (117), Expect = 1e-05
Identities = 57/241 (23%), Positives = 81/241 (33%), Gaps = 24/241 (9%)
Query: 280 PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA 339
P P T P P + A P T TK+ P P P + P
Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 275
Query: 340 FPQAKSASRTPGDGVSRL-------PVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAA 392
A + ++ P ++ P K+PA +TP P +E P P PA
Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA- 334
Query: 393 NLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGP 452
P+ + + +TP P + + P + PK AP P+ P
Sbjct: 335 ------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-APTTTKEPS---PTT 384
Query: 453 PKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTS 512
PK+ A + T + TT PA P P T KE S + P P T+
Sbjct: 385 PKEPAPTTT---KSAPTTTKE--PA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 438
Query: 513 P 513
P
Sbjct: 439 P 439
Score = 47.0 bits (110), Expect = 7e-05
Identities = 66/262 (25%), Positives = 80/262 (30%), Gaps = 33/262 (12%)
Query: 245 TPPAGADSDSEESEAIYEEMKYPL-PEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRR 302
TP A + EE E P PEE P T P P P P +
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Query: 303 PASALPSRR-DGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA----------KSASRTP- 350
PA P TP T P + P P + P P K A TP
Sbjct: 562 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621
Query: 351 --GDGVSRLPVLCHSKEPAGSTPAPQVPARERE----TPPPPPPPPAANLLLLGPSGRAR 404
+ P KEPA +TP P +E TP P P A GP+
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681
Query: 405 SHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVY 464
P P+ + + P + PK AP P P PP VS T
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTT-----PKKP-APTTPETP------PPTTSEVS-TPTT 728
Query: 465 SAVKVTTHSVLPAGPPLGAGEP 486
+ T H P + EP
Sbjct: 729 TKEPTTIHKSPDESTPELSAEP 750
Score = 39.7 bits (91), Expect = 0.012
Identities = 61/297 (20%), Positives = 91/297 (30%), Gaps = 56/297 (18%)
Query: 265 KYPLPEEAGEGRANGP-------------------PPLTATSPPQQPHALPPHAHRRPAS 305
K P+ +EAG G NG P +T P +LPP++ +
Sbjct: 81 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 140
Query: 306 ALPSRRDGT-----------------PTKTTPCE----IPPPFPNLLQHRPPLLAFPQAK 344
+L ++ T KTT + I L +LA P K
Sbjct: 141 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 200
Query: 345 SASRTPGDGVS--RLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402
+ + T G ++ + P KEPA +TP P + P P P P+
Sbjct: 201 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP--------APTTT 252
Query: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPK------AAGAPAAPPAPAALLPGPPKDK 456
+ +TP P + P + K AP P PA P P
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312
Query: 457 AVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSP 513
+ + T + P P T KE + + P P T+P
Sbjct: 313 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 369
Score = 30.4 bits (67), Expect = 7.2
Identities = 55/293 (18%), Positives = 87/293 (29%), Gaps = 57/293 (19%)
Query: 105 LTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKP 164
LT + + P P + T + P + E P+ ++P P +++ P++P
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP---EEPAPTTPKAAAPNTPKEP 546
Query: 165 RRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVF 224
+P T + P P+ P +P ++P E+
Sbjct: 547 --APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 604
Query: 225 RGGGRSGGGLAGP--PLGGGGPTPPAGADSDSEE--------------SEAIYEEMKYPL 268
+ + P P G TP A + +E E K P
Sbjct: 605 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 664
Query: 269 PEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPP-- 325
P+E GP T+ P P P P + PA P + P TTP PP
Sbjct: 665 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK----PAPTTPETPPPTT 720
Query: 326 -----------------------------PFPNLLQHRPPLLAFPQAKSASRT 349
P P L++ P P K+ + T
Sbjct: 721 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 773
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 67.8 bits (164), Expect = 4e-11
Identities = 77/333 (23%), Positives = 107/333 (32%), Gaps = 26/333 (7%)
Query: 245 TPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPA 304
T + + E + +E P+E P P T S P P P ++PA
Sbjct: 292 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351
Query: 305 SALPSRRDGT----PTKTTPCEIPP----PFPNLLQHRPPLLAFPQAKSASRTPGDGVSR 356
P T PT TTP E P P P + P A + + P +
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 411
Query: 357 LPVLCHSKEPAGSTPAPQVPARERETP-----PPPPPPPAANLLLLGPSGRARSHSTPLP 411
P +KEP+ +TP P + P P P +A PS P
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471
Query: 412 PQGSGQPRGERELPNSHSMICPKAAGAPA-------APPAPAALLPGPPKDKAVSYTMVY 464
P+ ++ P + P PA AP P P PK+ A T
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP--TTPK 529
Query: 465 SAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGV 524
T + P P A P T +E++ T + P P T+P A
Sbjct: 530 KLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587
Query: 525 LHHRGCLASPHSLPDPTVGPLTPLWTYPATAAG 557
+P + +P P TP T P T G
Sbjct: 588 APTTPKEPAPTTPKEP--APTTPKETAPTTPKG 618
Score = 62.0 bits (149), Expect = 2e-09
Identities = 101/455 (22%), Positives = 133/455 (29%), Gaps = 56/455 (12%)
Query: 109 SSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSP 168
++T+ P P+ T P + E P+ TP+ + K P + P
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389
Query: 169 NTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGG 228
+ P P+P P T+ +P +EP
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTK------EPSPTTPKEP------APTTTKSA 437
Query: 229 RSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSP 288
+ P PT P E S +E P+E P P T P
Sbjct: 438 PTTTKEPAPTTTKSAPTTP------KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491
Query: 289 -PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA--KS 345
P P P ++PA P P TTP E P P L P P K
Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547
Query: 346 ASRTPGD---GVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402
A TP + P +EPA +TP P +E P P PA P+
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT-TPKEPAPT 606
Query: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALL---PGPPKDKAVS 459
+ P P+G+ + P + PK AP P + P P K +
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTA 665
Query: 460 YTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMG 519
T T P P A P T KE P P K +P A
Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTA--PTTLKE-----------PAPTTPKKPAPKELAPT 712
Query: 520 AAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPAT 554
G P S P TP T P T
Sbjct: 713 TTKG----------PTSTTSDKPAPTTPKETAPTT 737
Score = 53.9 bits (128), Expect = 6e-07
Identities = 56/234 (23%), Positives = 72/234 (30%), Gaps = 19/234 (8%)
Query: 280 PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA 339
P P T S P P P + PA P T TK P + P
Sbjct: 288 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 347
Query: 340 FPQAKSASRTPGDGVSRLPVLCHSKEPAGST--PAPQVPARERETPPPPPPPPAANLLLL 397
A + + P + P KEPA +T PAP P T P P P
Sbjct: 348 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP-------- 399
Query: 398 GPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKA 457
+ + + +TP P + P + K+A PAP P K
Sbjct: 400 -TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458
Query: 458 VSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKT 511
S T T P P A P T KE + T+ + P P T
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPA--PTTPKEPAP------TTPKEPAPTTT 504
Score = 49.7 bits (117), Expect = 1e-05
Identities = 57/241 (23%), Positives = 81/241 (33%), Gaps = 24/241 (9%)
Query: 280 PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA 339
P P T P P + A P T TK+ P P P + P
Sbjct: 257 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 316
Query: 340 FPQAKSASRTPGDGVSRL-------PVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAA 392
A + ++ P ++ P K+PA +TP P +E P P PA
Sbjct: 317 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA- 375
Query: 393 NLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGP 452
P+ + + +TP P + + P + PK AP P+ P
Sbjct: 376 ------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-APTTTKEPS---PTT 425
Query: 453 PKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTS 512
PK+ A + T + TT PA P P T KE S + P P T+
Sbjct: 426 PKEPAPTTT---KSAPTTTKE--PA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 479
Query: 513 P 513
P
Sbjct: 480 P 480
Score = 47.0 bits (110), Expect = 7e-05
Identities = 66/262 (25%), Positives = 80/262 (30%), Gaps = 33/262 (12%)
Query: 245 TPPAGADSDSEESEAIYEEMKYPL-PEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRR 302
TP A + EE E P PEE P T P P P P +
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Query: 303 PASALPSRR-DGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA----------KSASRTP- 350
PA P TP T P + P P + P P K A TP
Sbjct: 603 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662
Query: 351 --GDGVSRLPVLCHSKEPAGSTPAPQVPARERE----TPPPPPPPPAANLLLLGPSGRAR 404
+ P KEPA +TP P +E TP P P A GP+
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722
Query: 405 SHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVY 464
P P+ + + P + PK AP P P PP VS T
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTT-----PKKP-APTTPETP------PPTTSEVS-TPTT 769
Query: 465 SAVKVTTHSVLPAGPPLGAGEP 486
+ T H P + EP
Sbjct: 770 TKEPTTIHKSPDESTPELSAEP 791
Score = 39.7 bits (91), Expect = 0.012
Identities = 61/297 (20%), Positives = 91/297 (30%), Gaps = 56/297 (18%)
Query: 265 KYPLPEEAGEGRANGP-------------------PPLTATSPPQQPHALPPHAHRRPAS 305
K P+ +EAG G NG P +T P +LPP++ +
Sbjct: 122 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 181
Query: 306 ALPSRRDGT-----------------PTKTTPCE----IPPPFPNLLQHRPPLLAFPQAK 344
+L ++ T KTT + I L +LA P K
Sbjct: 182 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 241
Query: 345 SASRTPGDGVS--RLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402
+ + T G ++ + P KEPA +TP P + P P P P+
Sbjct: 242 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP--------APTTT 293
Query: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPK------AAGAPAAPPAPAALLPGPPKDK 456
+ +TP P + P + K AP P PA P P
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353
Query: 457 AVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSP 513
+ + T + P P T KE + + P P T+P
Sbjct: 354 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 410
Score = 30.4 bits (67), Expect = 7.2
Identities = 55/293 (18%), Positives = 87/293 (29%), Gaps = 57/293 (19%)
Query: 105 LTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKP 164
LT + + P P + T + P + E P+ ++P P +++ P++P
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP---EEPAPTTPKAAAPNTPKEP 587
Query: 165 RRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVF 224
+P T + P P+ P +P ++P E+
Sbjct: 588 --APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 645
Query: 225 RGGGRSGGGLAGP--PLGGGGPTPPAGADSDSEE--------------SEAIYEEMKYPL 268
+ + P P G TP A + +E E K P
Sbjct: 646 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 705
Query: 269 PEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPP-- 325
P+E GP T+ P P P P + PA P + P TTP PP
Sbjct: 706 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK----PAPTTPETPPPTT 761
Query: 326 -----------------------------PFPNLLQHRPPLLAFPQAKSASRT 349
P P L++ P P K+ + T
Sbjct: 762 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 814
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 67.8 bits (164), Expect = 4e-11
Identities = 77/333 (23%), Positives = 107/333 (32%), Gaps = 26/333 (7%)
Query: 245 TPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPA 304
T + + E + +E P+E P P T S P P P ++PA
Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 305 SALPSRRDGT----PTKTTPCEIPP----PFPNLLQHRPPLLAFPQAKSASRTPGDGVSR 356
P T PT TTP E P P P + P A + + P +
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Query: 357 LPVLCHSKEPAGSTPAPQVPARERETP-----PPPPPPPAANLLLLGPSGRARSHSTPLP 411
P +KEP+ +TP P + P P P +A PS P
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523
Query: 412 PQGSGQPRGERELPNSHSMICPKAAGAPA-------APPAPAALLPGPPKDKAVSYTMVY 464
P+ ++ P + P PA AP P P PK+ A T
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP--TTPK 581
Query: 465 SAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGV 524
T + P P A P T +E++ T + P P T+P A
Sbjct: 582 KLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 639
Query: 525 LHHRGCLASPHSLPDPTVGPLTPLWTYPATAAG 557
+P + +P P TP T P T G
Sbjct: 640 APTTPKEPAPTTPKEP--APTTPKETAPTTPKG 670
Score = 62.0 bits (149), Expect = 2e-09
Identities = 101/455 (22%), Positives = 133/455 (29%), Gaps = 56/455 (12%)
Query: 109 SSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSP 168
++T+ P P+ T P + E P+ TP+ + K P + P
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441
Query: 169 NTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGG 228
+ P P+P P T+ +P +EP
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTK------EPSPTTPKEP------APTTTKSA 489
Query: 229 RSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSP 288
+ P PT P E S +E P+E P P T P
Sbjct: 490 PTTTKEPAPTTTKSAPTTP------KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543
Query: 289 -PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA--KS 345
P P P ++PA P P TTP E P P L P P K
Sbjct: 544 APTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599
Query: 346 ASRTPGD---GVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402
A TP + P +EPA +TP P +E P P PA P+
Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT-TPKEPAPT 658
Query: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALL---PGPPKDKAVS 459
+ P P+G+ + P + PK AP P + P P K +
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTA 717
Query: 460 YTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMG 519
T T P P A P T KE P P K +P A
Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTA--PTTLKE-----------PAPTTPKKPAPKELAPT 764
Query: 520 AAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPAT 554
G P S P TP T P T
Sbjct: 765 TTKG----------PTSTTSDKPAPTTPKETAPTT 789
Score = 53.9 bits (128), Expect = 6e-07
Identities = 56/234 (23%), Positives = 72/234 (30%), Gaps = 19/234 (8%)
Query: 280 PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA 339
P P T S P P P + PA P T TK P + P
Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399
Query: 340 FPQAKSASRTPGDGVSRLPVLCHSKEPAGST--PAPQVPARERETPPPPPPPPAANLLLL 397
A + + P + P KEPA +T PAP P T P P P
Sbjct: 400 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP-------- 451
Query: 398 GPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKA 457
+ + + +TP P + P + K+A PAP P K
Sbjct: 452 -TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510
Query: 458 VSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKT 511
S T T P P A P T KE + T+ + P P T
Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPA--PTTPKEPAP------TTPKEPAPTTT 556
Score = 49.7 bits (117), Expect = 1e-05
Identities = 57/241 (23%), Positives = 81/241 (33%), Gaps = 24/241 (9%)
Query: 280 PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA 339
P P T P P + A P T TK+ P P P + P
Sbjct: 309 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 368
Query: 340 FPQAKSASRTPGDGVSRL-------PVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAA 392
A + ++ P ++ P K+PA +TP P +E P P PA
Sbjct: 369 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA- 427
Query: 393 NLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGP 452
P+ + + +TP P + + P + PK AP P+ P
Sbjct: 428 ------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-APTTTKEPS---PTT 477
Query: 453 PKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTS 512
PK+ A + T + TT PA P P T KE S + P P T+
Sbjct: 478 PKEPAPTTT---KSAPTTTKE--PA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 531
Query: 513 P 513
P
Sbjct: 532 P 532
Score = 47.0 bits (110), Expect = 7e-05
Identities = 66/262 (25%), Positives = 80/262 (30%), Gaps = 33/262 (12%)
Query: 245 TPPAGADSDSEESEAIYEEMKYPL-PEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRR 302
TP A + EE E P PEE P T P P P P +
Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654
Query: 303 PASALPSRR-DGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA----------KSASRTP- 350
PA P TP T P + P P + P P K A TP
Sbjct: 655 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 351 --GDGVSRLPVLCHSKEPAGSTPAPQVPARERE----TPPPPPPPPAANLLLLGPSGRAR 404
+ P KEPA +TP P +E TP P P A GP+
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774
Query: 405 SHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVY 464
P P+ + + P + PK AP P P PP VS T
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTT-----PKKP-APTTPETP------PPTTSEVS-TPTT 821
Query: 465 SAVKVTTHSVLPAGPPLGAGEP 486
+ T H P + EP
Sbjct: 822 TKEPTTIHKSPDESTPELSAEP 843
Score = 39.7 bits (91), Expect = 0.012
Identities = 61/297 (20%), Positives = 91/297 (30%), Gaps = 56/297 (18%)
Query: 265 KYPLPEEAGEGRANGP-------------------PPLTATSPPQQPHALPPHAHRRPAS 305
K P+ +EAG G NG P +T P +LPP++ +
Sbjct: 174 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 233
Query: 306 ALPSRRDGT-----------------PTKTTPCE----IPPPFPNLLQHRPPLLAFPQAK 344
+L ++ T KTT + I L +LA P K
Sbjct: 234 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 293
Query: 345 SASRTPGDGVS--RLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402
+ + T G ++ + P KEPA +TP P + P P P P+
Sbjct: 294 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP--------APTTT 345
Query: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPK------AAGAPAAPPAPAALLPGPPKDK 456
+ +TP P + P + K AP P PA P P
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 457 AVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSP 513
+ + T + P P T KE + + P P T+P
Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 462
Score = 30.4 bits (67), Expect = 7.2
Identities = 55/293 (18%), Positives = 87/293 (29%), Gaps = 57/293 (19%)
Query: 105 LTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKP 164
LT + + P P + T + P + E P+ ++P P +++ P++P
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP---EEPAPTTPKAAAPNTPKEP 639
Query: 165 RRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVF 224
+P T + P P+ P +P ++P E+
Sbjct: 640 --APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 697
Query: 225 RGGGRSGGGLAGP--PLGGGGPTPPAGADSDSEE--------------SEAIYEEMKYPL 268
+ + P P G TP A + +E E K P
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 757
Query: 269 PEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPP-- 325
P+E GP T+ P P P P + PA P + P TTP PP
Sbjct: 758 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK----PAPTTPETPPPTT 813
Query: 326 -----------------------------PFPNLLQHRPPLLAFPQAKSASRT 349
P P L++ P P K+ + T
Sbjct: 814 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 866
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 67.8 bits (164), Expect = 4e-11
Identities = 77/333 (23%), Positives = 107/333 (32%), Gaps = 26/333 (7%)
Query: 245 TPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPA 304
T + + E + +E P+E P P T S P P P ++PA
Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 305 SALPSRRDGT----PTKTTPCEIPP----PFPNLLQHRPPLLAFPQAKSASRTPGDGVSR 356
P T PT TTP E P P P + P A + + P +
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 357 LPVLCHSKEPAGSTPAPQVPARERETP-----PPPPPPPAANLLLLGPSGRARSHSTPLP 411
P +KEP+ +TP P + P P P +A PS P
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564
Query: 412 PQGSGQPRGERELPNSHSMICPKAAGAPA-------APPAPAALLPGPPKDKAVSYTMVY 464
P+ ++ P + P PA AP P P PK+ A T
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP--TTPK 622
Query: 465 SAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGV 524
T + P P A P T +E++ T + P P T+P A
Sbjct: 623 KLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 680
Query: 525 LHHRGCLASPHSLPDPTVGPLTPLWTYPATAAG 557
+P + +P P TP T P T G
Sbjct: 681 APTTPKEPAPTTPKEP--APTTPKETAPTTPKG 711
Score = 62.0 bits (149), Expect = 2e-09
Identities = 101/455 (22%), Positives = 133/455 (29%), Gaps = 56/455 (12%)
Query: 109 SSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSP 168
++T+ P P+ T P + E P+ TP+ + K P + P
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482
Query: 169 NTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGG 228
+ P P+P P T+ +P +EP
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTK------EPSPTTPKEP------APTTTKSA 530
Query: 229 RSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSP 288
+ P PT P E S +E P+E P P T P
Sbjct: 531 PTTTKEPAPTTTKSAPTTP------KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584
Query: 289 -PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA--KS 345
P P P ++PA P P TTP E P P L P P K
Sbjct: 585 APTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640
Query: 346 ASRTPGD---GVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402
A TP + P +EPA +TP P +E P P PA P+
Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT-TPKEPAPT 699
Query: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALL---PGPPKDKAVS 459
+ P P+G+ + P + PK AP P + P P K +
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTA 758
Query: 460 YTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMG 519
T T P P A P T KE P P K +P A
Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTA--PTTLKE-----------PAPTTPKKPAPKELAPT 805
Query: 520 AAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPAT 554
G P S P TP T P T
Sbjct: 806 TTKG----------PTSTTSDKPAPTTPKETAPTT 830
Score = 53.9 bits (128), Expect = 6e-07
Identities = 56/234 (23%), Positives = 72/234 (30%), Gaps = 19/234 (8%)
Query: 280 PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA 339
P P T S P P P + PA P T TK P + P
Sbjct: 381 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440
Query: 340 FPQAKSASRTPGDGVSRLPVLCHSKEPAGST--PAPQVPARERETPPPPPPPPAANLLLL 397
A + + P + P KEPA +T PAP P T P P P
Sbjct: 441 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP-------- 492
Query: 398 GPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKA 457
+ + + +TP P + P + K+A PAP P K
Sbjct: 493 -TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551
Query: 458 VSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKT 511
S T T P P A P T KE + T+ + P P T
Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPA--PTTPKEPAP------TTPKEPAPTTT 597
Score = 49.7 bits (117), Expect = 1e-05
Identities = 57/241 (23%), Positives = 81/241 (33%), Gaps = 24/241 (9%)
Query: 280 PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA 339
P P T P P + A P T TK+ P P P + P
Sbjct: 350 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 409
Query: 340 FPQAKSASRTPGDGVSRL-------PVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAA 392
A + ++ P ++ P K+PA +TP P +E P P PA
Sbjct: 410 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA- 468
Query: 393 NLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGP 452
P+ + + +TP P + + P + PK AP P+ P
Sbjct: 469 ------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-APTTTKEPS---PTT 518
Query: 453 PKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTS 512
PK+ A + T + TT PA P P T KE S + P P T+
Sbjct: 519 PKEPAPTTT---KSAPTTTKE--PA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 572
Query: 513 P 513
P
Sbjct: 573 P 573
Score = 47.0 bits (110), Expect = 7e-05
Identities = 66/262 (25%), Positives = 80/262 (30%), Gaps = 33/262 (12%)
Query: 245 TPPAGADSDSEESEAIYEEMKYPL-PEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRR 302
TP A + EE E P PEE P T P P P P +
Sbjct: 636 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695
Query: 303 PASALPSRR-DGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA----------KSASRTP- 350
PA P TP T P + P P + P P K A TP
Sbjct: 696 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 351 --GDGVSRLPVLCHSKEPAGSTPAPQVPARERE----TPPPPPPPPAANLLLLGPSGRAR 404
+ P KEPA +TP P +E TP P P A GP+
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815
Query: 405 SHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVY 464
P P+ + + P + PK AP P P PP VS T
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTT-----PKKP-APTTPETP------PPTTSEVS-TPTT 862
Query: 465 SAVKVTTHSVLPAGPPLGAGEP 486
+ T H P + EP
Sbjct: 863 TKEPTTIHKSPDESTPELSAEP 884
Score = 39.7 bits (91), Expect = 0.012
Identities = 61/297 (20%), Positives = 91/297 (30%), Gaps = 56/297 (18%)
Query: 265 KYPLPEEAGEGRANGP-------------------PPLTATSPPQQPHALPPHAHRRPAS 305
K P+ +EAG G NG P +T P +LPP++ +
Sbjct: 215 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 274
Query: 306 ALPSRRDGT-----------------PTKTTPCE----IPPPFPNLLQHRPPLLAFPQAK 344
+L ++ T KTT + I L +LA P K
Sbjct: 275 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 334
Query: 345 SASRTPGDGVS--RLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402
+ + T G ++ + P KEPA +TP P + P P P P+
Sbjct: 335 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP--------APTTT 386
Query: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPK------AAGAPAAPPAPAALLPGPPKDK 456
+ +TP P + P + K AP P PA P P
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 457 AVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSP 513
+ + T + P P T KE + + P P T+P
Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 503
Score = 30.4 bits (67), Expect = 7.2
Identities = 55/293 (18%), Positives = 87/293 (29%), Gaps = 57/293 (19%)
Query: 105 LTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKP 164
LT + + P P + T + P + E P+ ++P P +++ P++P
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP---EEPAPTTPKAAAPNTPKEP 680
Query: 165 RRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVF 224
+P T + P P+ P +P ++P E+
Sbjct: 681 --APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 738
Query: 225 RGGGRSGGGLAGP--PLGGGGPTPPAGADSDSEE--------------SEAIYEEMKYPL 268
+ + P P G TP A + +E E K P
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 798
Query: 269 PEEAGEGRANGPPPLTATSP-PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPP-- 325
P+E GP T+ P P P P + PA P + P TTP PP
Sbjct: 799 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK----PAPTTPETPPPTT 854
Query: 326 -----------------------------PFPNLLQHRPPLLAFPQAKSASRT 349
P P L++ P P K+ + T
Sbjct: 855 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 907
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 67.8 bits (164), Expect = 4e-11
Identities = 111/492 (22%), Positives = 158/492 (32%), Gaps = 85/492 (17%)
Query: 10 LEWRQHKEEEAKRSSSKEVAPA-------------GSAGPAAGQGPGVRVRDIASLRRSL 56
++ RQ+K+ + RS K+ AP G ++ G + R A +
Sbjct: 1 MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTA---KKA 57
Query: 57 RMGFMTMPA------SQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSS 110
R+ + P S+E + AP+ G D
Sbjct: 58 RVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDG 117
Query: 111 TRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNT 170
+ P + + ST S+ PGS S SQ P P +P S
Sbjct: 118 SSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR 177
Query: 171 QLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEP-VYIEMVGDVFRGG-- 227
Q SF+ P +P G + P++ T SR+ P P +Y G V G
Sbjct: 178 QPEASFEPH--PSVTPTGYHAPMEPPT--SRMFQAPPGAPPPHPQLYPGGTGGVLSGPPM 233
Query: 228 GRSGGGLA---GPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLT 284
G GGG A G P GG PP S S + K P G + PPP
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 285 --------------------ATSPP---QQP---HALPPHAHRRPASALPSRRDGTPTKT 318
+ SPP QP H PHA + LP + PT
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 319 -TPCEIPP------------PFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKE 365
+P +PP P+ + + + S+S +P LP HS
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
Query: 366 PAGSTPA---------PQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSG 416
P S P +P++ + PPPPPP LL + +H P PP
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLL-----ANSNAHPGPFPPSTGA 468
Query: 417 QPRGERELPNSH 428
Q + H
Sbjct: 469 QSTAHPPVSTHH 480
Score = 61.2 bits (147), Expect = 4e-09
Identities = 135/545 (24%), Positives = 176/545 (32%), Gaps = 113/545 (20%)
Query: 114 PPAKPRRHPSTKLSMVGPGSGAETPP-SKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQL 172
PP P HP +L G G PP K G + G ++ PP P T +
Sbjct: 209 PPGAPPPHP--QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP------PTTPI 260
Query: 173 SVSFD--ESCPPGPSPR----GGNLP--------------------LQRLTRGSRVAGDP 206
SVS PP P GGNLP L+ L S A P
Sbjct: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNAS--ASPP 318
Query: 207 DVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPT-PPAGADSDSEESEAIYEEMK 265
+GAQ P ++ + G+ GGL PP GPT P+ S A M+
Sbjct: 319 GLGAQPLPGHLPSPHAM----GQGMGGL--PPGPEKGPTLAPSPHSLPPASSSAPAPPMR 372
Query: 266 YPLPEEAGEGRA---NGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPC- 321
+P + A + ++ SP ALP + H P S + P T P
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432
Query: 322 ----------EIPPPFPNLLQ----HRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPA 367
PPP+ LL H P FP + A T VS ++
Sbjct: 433 PSQAVWSQGPPPPPPYGRLLANSNAHPGP---FPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
Query: 368 GSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQ-GSGQPR--GEREL 424
Q +++ PPPP A L +H + P GS +P G L
Sbjct: 490 QQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL 549
Query: 425 PNSHSMICPKAAGA--------------------PAAPPAPA-----ALLPGPPKDKAVS 459
P HS + AG P + P+P+ A P PP +
Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609
Query: 460 YTMVYSAVKVTTHSVLPAG---------PPLGAGEP-----KTEKEISVLHGM---LCTS 502
+ S V T S PAG PP G P KT G T
Sbjct: 610 SSATLSTVIATVASS-PAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTG 668
Query: 503 SRPPVPGKTSPHGGAMGAAAGVLHHRGCL--ASPHSLPDPTVGPLTPLWTYPATAAGLKR 560
+ P G + P G G L A P LP P P P +A +K+
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728
Query: 561 PPAYE 565
PA E
Sbjct: 729 EPAEE 733
Score = 49.7 bits (117), Expect = 1e-05
Identities = 71/250 (28%), Positives = 90/250 (36%), Gaps = 37/250 (14%)
Query: 333 HRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTP----APQVPARERETPPPPPP 388
H PPL FP S P D R P P+ TP AP P R PP
Sbjct: 160 HPPPL--FPP----SPQPPDSTPRQPEASFEPHPS-VTPTGYHAPMEPPTSRMFQAPPGA 212
Query: 389 PPAANLLLLGPSGRARSHSTPLPPQGSGQ------PRGERELPNSHSMICPKAAGAPAAP 442
PP L G +G S P+ P+G G P G ++ P + I ++GA AP
Sbjct: 213 PPPHPQLYPGGTGGVLS-GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAP 271
Query: 443 PAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTS 502
P PP + + V P PP A P S G+
Sbjct: 272 PTK------PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP-PGL---- 320
Query: 503 SRPPVPGK-TSPHGGAMGAAAGVL---HHRG--CLASPHSLPDPTVGPLTPLWTYPATAA 556
P+PG SPH AMG G L +G SPHSLP + P +P +++
Sbjct: 321 GAQPLPGHLPSPH--AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSS 378
Query: 557 GLKRPPAYES 566
A S
Sbjct: 379 SSSSAAASSS 388
Score = 46.6 bits (109), Expect = 1e-04
Identities = 64/256 (25%), Positives = 80/256 (31%), Gaps = 45/256 (17%)
Query: 140 SKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRG 199
S GS +P P G P P VS+ ++ P GP + ++G
Sbjct: 533 SPSLGSLRPYPPG-----------PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQG 581
Query: 200 SRVAG--DPDVGAQEEPVYIEMVGDVFRGGGRSG---GGLAGPPLGGGGPTPPAGADSDS 254
S P G Q P V V +A P G +PP
Sbjct: 582 SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641
Query: 255 EE-SEAIYEEMKYP--LPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRR 311
S Y+ P P R PP TSPP P P
Sbjct: 642 RAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP-------------- 687
Query: 312 DGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTP 371
G+PT P +PP P+ L PP P A AS P L +EPA
Sbjct: 688 -GSPT-VGPGPLPPAGPSGLPSLPP----PPAAPASGPP------LSATQIKQEPAEEYE 735
Query: 372 APQVPARERETPPPPP 387
P+ P +P PPP
Sbjct: 736 TPESPVPPARSPSPPP 751
Score = 39.7 bits (91), Expect = 0.012
Identities = 92/421 (21%), Positives = 134/421 (31%), Gaps = 88/421 (20%)
Query: 84 SCHSVGSMDSVGGGPGGASGGLTEDSS-------TRRPPAKPRRHPSTKLSMVGPGSGAE 136
S H++G +GG P G G T S + PA P R P + S + +
Sbjct: 331 SPHAMGQ--GMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388
Query: 137 TPPSKKAGSQKPTPEGRES---------SRKVPPQKPRRSPNTQLSVSFDESCPPGPSPR 187
+ S + S P + S S V Q P+ + + S + PP P P
Sbjct: 389 SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY 448
Query: 188 GGNLPLQRL-------TRGSRVAGDPDVGAQ----EEPVYIEMVGDVFRGGGRSGGGLAG 236
G L + G++ P V ++ + + + G +G
Sbjct: 449 GRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508
Query: 237 PPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAG--------------EGRANGPP- 281
PP G P P G S A+ + P G + NGPP
Sbjct: 509 PPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPV 568
Query: 282 -------------------PLTATSPPQQPHALPPHAHRRPASALPSRRDGTPT------ 316
P + P P+ PP +SA S T
Sbjct: 569 SSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY 628
Query: 317 KTTPCEIPPPF------PNLLQHRPPLLAFPQAKSASRT---PGDGVSRLPVLCHSKEPA 367
KT PPP+ P + P P + + RT PG + P + +P
Sbjct: 629 KTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPG 688
Query: 368 GST--PAPQVPARERETP--PPPP------PPPAANLLLLGPSGRARSHSTPLPPQGSGQ 417
T P P PA P PPPP PP +A + P+ + +P+PP S
Sbjct: 689 SPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPS 748
Query: 418 P 418
P
Sbjct: 749 P 749
Score = 38.5 bits (88), Expect = 0.026
Identities = 72/311 (23%), Positives = 106/311 (34%), Gaps = 60/311 (19%)
Query: 13 RQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPH 72
+Q ++++ ++ ++ G++GP PG + + P+ P+
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPP---PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPY 542
Query: 73 PCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGP- 131
P A P HS S G S SST + + P HPS GP
Sbjct: 543 PPGPAHLPPP---HSQVSYSQAGPNGPPVSSSSNSSSSTSQG-SYPCSHPSPSQ---GPQ 595
Query: 132 GSGAETPPSKKAGSQKPT-----------PEG-RESSRKVPPQKPRRSPNTQLSVSFDES 179
G+ PP + T P G + +S PP +R+P+ ++ +
Sbjct: 596 GAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPG---AYKTA 652
Query: 180 CPPG------PSPRGGNLPLQRLTR-----GSRVAGDPDVGAQEEPVYIEMVGDVFRGGG 228
PPG PS R G P R T G+ G P VG P G
Sbjct: 653 TPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPP-----------AG 701
Query: 229 RSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSP 288
SG PP PP A +E YE + P+P P + SP
Sbjct: 702 PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP------------PARSPSP 749
Query: 289 PQQPHALPPHA 299
P + +P HA
Sbjct: 750 PPKVVDVPSHA 760
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 67.8 bits (164), Expect = 4e-11
Identities = 111/492 (22%), Positives = 158/492 (32%), Gaps = 85/492 (17%)
Query: 10 LEWRQHKEEEAKRSSSKEVAPA-------------GSAGPAAGQGPGVRVRDIASLRRSL 56
++ RQ+K+ + RS K+ AP G ++ G + R A +
Sbjct: 1 MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTA---KKA 57
Query: 57 RMGFMTMPA------SQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSS 110
R+ + P S+E + AP+ G D
Sbjct: 58 RVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDG 117
Query: 111 TRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNT 170
+ P + + ST S+ PGS S SQ P P +P S
Sbjct: 118 SSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR 177
Query: 171 QLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEP-VYIEMVGDVFRGG-- 227
Q SF+ P +P G + P++ T SR+ P P +Y G V G
Sbjct: 178 QPEASFEPH--PSVTPTGYHAPMEPPT--SRMFQAPPGAPPPHPQLYPGGTGGVLSGPPM 233
Query: 228 GRSGGGLA---GPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLT 284
G GGG A G P GG PP S S + K P G + PPP
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 285 --------------------ATSPP---QQP---HALPPHAHRRPASALPSRRDGTPTKT 318
+ SPP QP H PHA + LP + PT
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 319 -TPCEIPP------------PFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKE 365
+P +PP P+ + + + S+S +P LP HS
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
Query: 366 PAGSTPA---------PQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSG 416
P S P +P++ + PPPPPP LL + +H P PP
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLL-----ANSNAHPGPFPPSTGA 468
Query: 417 QPRGERELPNSH 428
Q + H
Sbjct: 469 QSTAHPPVSTHH 480
Score = 61.2 bits (147), Expect = 4e-09
Identities = 135/545 (24%), Positives = 176/545 (32%), Gaps = 113/545 (20%)
Query: 114 PPAKPRRHPSTKLSMVGPGSGAETPP-SKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQL 172
PP P HP +L G G PP K G + G ++ PP P T +
Sbjct: 209 PPGAPPPHP--QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP------PTTPI 260
Query: 173 SVSFD--ESCPPGPSPR----GGNLP--------------------LQRLTRGSRVAGDP 206
SVS PP P GGNLP L+ L S A P
Sbjct: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNAS--ASPP 318
Query: 207 DVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPT-PPAGADSDSEESEAIYEEMK 265
+GAQ P ++ + G+ GGL PP GPT P+ S A M+
Sbjct: 319 GLGAQPLPGHLPSPHAM----GQGMGGL--PPGPEKGPTLAPSPHSLPPASSSAPAPPMR 372
Query: 266 YPLPEEAGEGRA---NGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPC- 321
+P + A + ++ SP ALP + H P S + P T P
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432
Query: 322 ----------EIPPPFPNLLQ----HRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPA 367
PPP+ LL H P FP + A T VS ++
Sbjct: 433 PSQAVWSQGPPPPPPYGRLLANSNAHPGP---FPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
Query: 368 GSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQ-GSGQPR--GEREL 424
Q +++ PPPP A L +H + P GS +P G L
Sbjct: 490 QQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL 549
Query: 425 PNSHSMICPKAAGA--------------------PAAPPAPA-----ALLPGPPKDKAVS 459
P HS + AG P + P+P+ A P PP +
Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609
Query: 460 YTMVYSAVKVTTHSVLPAG---------PPLGAGEP-----KTEKEISVLHGM---LCTS 502
+ S V T S PAG PP G P KT G T
Sbjct: 610 SSATLSTVIATVASS-PAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTG 668
Query: 503 SRPPVPGKTSPHGGAMGAAAGVLHHRGCL--ASPHSLPDPTVGPLTPLWTYPATAAGLKR 560
+ P G + P G G L A P LP P P P +A +K+
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728
Query: 561 PPAYE 565
PA E
Sbjct: 729 EPAEE 733
Score = 49.7 bits (117), Expect = 1e-05
Identities = 71/250 (28%), Positives = 90/250 (36%), Gaps = 37/250 (14%)
Query: 333 HRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTP----APQVPARERETPPPPPP 388
H PPL FP S P D R P P+ TP AP P R PP
Sbjct: 160 HPPPL--FPP----SPQPPDSTPRQPEASFEPHPS-VTPTGYHAPMEPPTSRMFQAPPGA 212
Query: 389 PPAANLLLLGPSGRARSHSTPLPPQGSGQ------PRGERELPNSHSMICPKAAGAPAAP 442
PP L G +G S P+ P+G G P G ++ P + I ++GA AP
Sbjct: 213 PPPHPQLYPGGTGGVLS-GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAP 271
Query: 443 PAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTS 502
P PP + + V P PP A P S G+
Sbjct: 272 PTK------PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP-PGL---- 320
Query: 503 SRPPVPGK-TSPHGGAMGAAAGVL---HHRG--CLASPHSLPDPTVGPLTPLWTYPATAA 556
P+PG SPH AMG G L +G SPHSLP + P +P +++
Sbjct: 321 GAQPLPGHLPSPH--AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSS 378
Query: 557 GLKRPPAYES 566
A S
Sbjct: 379 SSSSAAASSS 388
Score = 46.6 bits (109), Expect = 1e-04
Identities = 64/256 (25%), Positives = 80/256 (31%), Gaps = 45/256 (17%)
Query: 140 SKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRG 199
S GS +P P G P P VS+ ++ P GP + ++G
Sbjct: 533 SPSLGSLRPYPPG-----------PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQG 581
Query: 200 SRVAG--DPDVGAQEEPVYIEMVGDVFRGGGRSG---GGLAGPPLGGGGPTPPAGADSDS 254
S P G Q P V V +A P G +PP
Sbjct: 582 SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641
Query: 255 EE-SEAIYEEMKYP--LPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRR 311
S Y+ P P R PP TSPP P P
Sbjct: 642 RAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP-------------- 687
Query: 312 DGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTP 371
G+PT P +PP P+ L PP P A AS P L +EPA
Sbjct: 688 -GSPT-VGPGPLPPAGPSGLPSLPP----PPAAPASGPP------LSATQIKQEPAEEYE 735
Query: 372 APQVPARERETPPPPP 387
P+ P +P PPP
Sbjct: 736 TPESPVPPARSPSPPP 751
Score = 39.7 bits (91), Expect = 0.012
Identities = 92/421 (21%), Positives = 134/421 (31%), Gaps = 88/421 (20%)
Query: 84 SCHSVGSMDSVGGGPGGASGGLTEDSS-------TRRPPAKPRRHPSTKLSMVGPGSGAE 136
S H++G +GG P G G T S + PA P R P + S + +
Sbjct: 331 SPHAMGQ--GMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388
Query: 137 TPPSKKAGSQKPTPEGRES---------SRKVPPQKPRRSPNTQLSVSFDESCPPGPSPR 187
+ S + S P + S S V Q P+ + + S + PP P P
Sbjct: 389 SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY 448
Query: 188 GGNLPLQRL-------TRGSRVAGDPDVGAQ----EEPVYIEMVGDVFRGGGRSGGGLAG 236
G L + G++ P V ++ + + + G +G
Sbjct: 449 GRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508
Query: 237 PPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAG--------------EGRANGPP- 281
PP G P P G S A+ + P G + NGPP
Sbjct: 509 PPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPV 568
Query: 282 -------------------PLTATSPPQQPHALPPHAHRRPASALPSRRDGTPT------ 316
P + P P+ PP +SA S T
Sbjct: 569 SSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY 628
Query: 317 KTTPCEIPPPF------PNLLQHRPPLLAFPQAKSASRT---PGDGVSRLPVLCHSKEPA 367
KT PPP+ P + P P + + RT PG + P + +P
Sbjct: 629 KTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPG 688
Query: 368 GST--PAPQVPARERETP--PPPP------PPPAANLLLLGPSGRARSHSTPLPPQGSGQ 417
T P P PA P PPPP PP +A + P+ + +P+PP S
Sbjct: 689 SPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPS 748
Query: 418 P 418
P
Sbjct: 749 P 749
Score = 38.5 bits (88), Expect = 0.026
Identities = 72/311 (23%), Positives = 106/311 (34%), Gaps = 60/311 (19%)
Query: 13 RQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPH 72
+Q ++++ ++ ++ G++GP PG + + P+ P+
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPP---PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPY 542
Query: 73 PCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGP- 131
P A P HS S G S SST + + P HPS GP
Sbjct: 543 PPGPAHLPPP---HSQVSYSQAGPNGPPVSSSSNSSSSTSQG-SYPCSHPSPSQ---GPQ 595
Query: 132 GSGAETPPSKKAGSQKPT-----------PEG-RESSRKVPPQKPRRSPNTQLSVSFDES 179
G+ PP + T P G + +S PP +R+P+ ++ +
Sbjct: 596 GAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPG---AYKTA 652
Query: 180 CPPG------PSPRGGNLPLQRLTR-----GSRVAGDPDVGAQEEPVYIEMVGDVFRGGG 228
PPG PS R G P R T G+ G P VG P G
Sbjct: 653 TPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPP-----------AG 701
Query: 229 RSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSP 288
SG PP PP A +E YE + P+P P + SP
Sbjct: 702 PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP------------PARSPSP 749
Query: 289 PQQPHALPPHA 299
P + +P HA
Sbjct: 750 PPKVVDVPSHA 760
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 67.0 bits (162), Expect = 7e-11
Identities = 108/485 (22%), Positives = 162/485 (33%), Gaps = 73/485 (15%)
Query: 6 RKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIA-SLRRSLRMGFMTMP 64
+ +K E + K RS SK + S P+ + P R R + S R P
Sbjct: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTR-PRRRHRSRSRSYSPRRRPSPRRRP 321
Query: 65 ASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPST 124
+ + TP P R PR S S + S +R PP KP + S+
Sbjct: 322 SPRRRTP-PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380
Query: 125 KLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVS--------- 175
S + +PP ++ P ++ PQ+ R+ +++SVS
Sbjct: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440
Query: 176 ------FDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGR 229
ES P P PR L +G ++A V + + +R +
Sbjct: 441 KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQ----------YRRQNQ 490
Query: 230 SGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPP 289
+ +G+ S SE+ +K E G R + P + SP
Sbjct: 491 QS-------------SSDSGSSSSSEDERPKRSHVK---NGEVGRRRRHSPSRSASPSPR 534
Query: 290 QQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRT 349
++ P RR + + P R + +P PPP PP P R+
Sbjct: 535 KRQKETSPRGRRRRSPSPPPTR----RRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRS 590
Query: 350 PGDGVSRLPV---LCHSKEPAGSTPAPQVPARERETPPPPP-------PPPAANLLLLGP 399
P P+ S P T +P P + R +P PPP PPP P
Sbjct: 591 PSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQR---SSP 647
Query: 400 SGRARSHS-TPLPPQGSGQPRGEREL----PNSHSMICPKAAGAPAAPPAPAALLPGPPK 454
+ RS S + +GS R RE PN P+ P AP PP
Sbjct: 648 VTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPR-------PRAPQTSSSPPPV 700
Query: 455 DKAVS 459
+ S
Sbjct: 701 RRGAS 705
Score = 51.6 bits (122), Expect = 3e-06
Identities = 122/560 (21%), Positives = 179/560 (31%), Gaps = 124/560 (22%)
Query: 21 KRSSSKEVAPAGSAGPAAGQGPGVRV--RDIASLRRSLRMGFMTMPASQEHTPHPCRSAM 78
+RSS+ + S+ + + P + R + R++ R+ P + H P P
Sbjct: 349 RRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSP---PA 405
Query: 79 APRSLSCHSVGSMDS-------VGGGPGGASGGLTEDSSTRR-----PPAKPRRHPSTKL 126
P + HS S V PG SG +T+ T + P KPR+ ++
Sbjct: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSES 465
Query: 127 S------MVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESC 180
M S + ++ Q + G SS + ++P+RS V
Sbjct: 466 EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE--DERPKRSHVKNGEVGRRRRH 523
Query: 181 PPG----PSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAG 236
P PSPR R R P + P
Sbjct: 524 SPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS---------PAPPPRRRRTPT 574
Query: 237 PPLGGGGPTPPAGADSDSEESEAIYEEMKY-PLPEEAGEGRANGPPPLTATSPPQQP--- 292
PP P+PP S S + + +Y P P + PPP SP P
Sbjct: 575 PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRR 634
Query: 293 --HALPPHAH-------RRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQA 343
H+ PP R P+ + R+ +P+++T E P PN P PQ
Sbjct: 635 VSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTR-EARSPQPNKRHSPSPRPRAPQT 693
Query: 344 KSASRTPGDGVSRLPVLCHSKEPA------------------GSTPAPQ----------- 374
S+ G S P S P+ ++P+PQ
Sbjct: 694 SSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSV 753
Query: 375 --VPARERETPPPPPPP-----PAANLLLLGPSGRARSHS-TPLPPQGSGQPRGERELPN 426
P + PP PP P P+ N P +A+S + +P PP+ S Q G ++
Sbjct: 754 SGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKK 813
Query: 427 SHSMICPK---------------AAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTT 471
K A A AA PAA+ A TT
Sbjct: 814 KKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAI-----------------AAATTT 856
Query: 472 HSVLPAGPPLGAGEPKTEKE 491
L P+ A EPK E E
Sbjct: 857 ---LAQEEPVAAPEPKKETE 873
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 66.2 bits (160), Expect = 1e-10
Identities = 115/503 (22%), Positives = 152/503 (30%), Gaps = 98/503 (19%)
Query: 63 MPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHP 122
+ AS H H R+ + ++G+ V G P GA+G PA P
Sbjct: 33 LAASAAHHHHLAPRTPEVRAAAAGALGN-HVVSGSPAGAAGA---------GPAAPAEG- 81
Query: 123 STKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPP 182
PG+ E PP+ +A P G R PP PRR P
Sbjct: 82 -------APGAAPEPPPAGRA-----RPGGGGPQRPGPPS-PRRP-----------LVPA 117
Query: 183 GPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGG 242
GP+P L P G+ + V AGP
Sbjct: 118 GPAPPAAKLR------------PPPEGSAGSCAPVPAAAAV----------AAGPEPAPA 155
Query: 243 GPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRR 302
GP PAG + L AG G GP P P +
Sbjct: 156 GPAKPAGPAA---------------LAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG 200
Query: 303 PASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCH 362
A+ L S P + L + P P K A+ PG + P +
Sbjct: 201 SAALLNSHHAAAPAVS------------LVNNGPAALLPLPKPAA--PGTVIQTPPFVGA 246
Query: 363 SKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHST---PLPPQGSGQPR 419
+ PA + P+P PPPPP A L P G T +PP + Q
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306
Query: 420 GERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGP 479
G + + AG P AA P KA S V A ++ +GP
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGP 366
Query: 480 PLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPD 539
A + G L + + P P +P G GAA V S P
Sbjct: 367 ASTAASMVIG---PTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQ------SLSRTPT 417
Query: 540 PTVGPLTPLWTYPATAAGLKRPP 562
T + T A L +PP
Sbjct: 418 ATTSGIRATLTPTVLAPRLPQPP 440
Score = 30.0 bits (66), Expect = 9.3
Identities = 67/272 (24%), Positives = 81/272 (29%), Gaps = 67/272 (24%)
Query: 520 AAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKG--- 576
AAAG L + SP GP P P A + PPA + GG +
Sbjct: 53 AAAGALGNHVVSGSPAGAAG--AGPAAPAEGAPGAAP--EPPPAGRARPGGGGPQRPGPP 108
Query: 577 ------CGVGAPSPMVKIQLQEQGTDGGAFASISCAHVIASAGTPEEEEEEVGAATFGAG 630
G P K++ +G+ G SCA V A+A E AG
Sbjct: 109 SPRRPLVPAGPAPPAAKLRPPPEGSAG------SCAPVPAAAAVAAGPEPAPAGPAKPAG 162
Query: 631 WALQRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSGIPVRSQGAEGLL 690
A ARA G GPG GPG P +Q G
Sbjct: 163 PAAL------------------AARAGPGPGPGPGP--GPGPGPGKPAGPGAAQTLNGSA 202
Query: 691 ARI--HHGD-------RGGSRTALPIPCQTFPACH-RNGDFTGGYRLGRSASTSGVRQVV 740
A + HH G LP+P P + F G
Sbjct: 203 ALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAA-------------- 248
Query: 741 LHTPRPCSQPRDALSQPHPALPLPLPLPPQPA 772
P P + A P PA P P PP PA
Sbjct: 249 --PPAPAAPSPPAA--PAPAAPAAAPPPPPPA 276
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 65.9 bits (159), Expect = 2e-10
Identities = 64/233 (27%), Positives = 86/233 (36%), Gaps = 15/233 (6%)
Query: 236 GPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHAL 295
GP P AG + + + EEM P E E + PP + TSPP + L
Sbjct: 410 GPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE--ESPLSPPPEESPTSPPPEASRL 467
Query: 296 PPHAHRRPASALPSRRD-GTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGV 354
P PAS LP P + +P PPP + L P F + + +P +
Sbjct: 468 SPPPEELPASPLPEALHLSRPLEESPLS-PPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 355 SRLPVLCHSKEPAGSTPAPQVPARERETPPPP-----PPPPAANLLLLGPSGRARSHSTP 409
P L P P E PPP PPP A+ L P S +P
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE---ESPMSP 583
Query: 410 LPPQGSGQPRGEREL---PNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVS 459
P + P E P S + P +P +PP A+ L PP+D +S
Sbjct: 584 PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
Score = 58.9 bits (141), Expect = 2e-08
Identities = 135/562 (24%), Positives = 184/562 (32%), Gaps = 151/562 (26%)
Query: 96 GGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAET----PPSKKAGSQKPTPE 151
G P +G T +PPA S+ GP S E PP A P
Sbjct: 2127 GSPTTPAGLSTSADGFLKPPAG---------SVPGPDSPGELFLKLPPQVPAQVPSQDPF 2177
Query: 152 GRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRV-AGDPD--- 207
G + + P+ P P + PP PSP G L SR AG P
Sbjct: 2178 GLAPAYPLEPRFPTAPP----------TYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFH 2227
Query: 208 VGAQEEPVYIEMVGDVFR------------------GGGRSGGGLAGPP----------- 238
P + D F GGG++ L PP
Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEV 2287
Query: 239 ----LGGGGPT--PP--AGADSDSEESEAIYEEMKYP--------------LPEEAGEG- 275
LG P+ PP DS S + E+K P P+ G G
Sbjct: 2288 KKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGL 2347
Query: 276 RANGPPPLTAT--SPPQQPHALPPHAHRRPASALP-SRRDGTPTKTTPCEIPP-PFPNLL 331
R PPP A SPP P P ++ P + P + R P + C +PP P+
Sbjct: 2348 RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP 2407
Query: 332 QHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETP-------- 383
R P A PQ++S+S++P ++ P+ + P+ TP Q P P
Sbjct: 2408 FSRVP--ASPQSQSSSQSP---LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDP 2462
Query: 384 ------PPPPPPP-----AANLLLLGPSGRARSHSTPLPPQG-------SGQPRGERELP 425
PP P PP A +L + P P G SGQP P
Sbjct: 2463 FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP 2522
Query: 426 NSHSMI---------CPKAAGAPA-APPAPAALLPGP-------------PKDKAVSYTM 462
+ + + P+A G P+ PP P LP P K ++ +YT
Sbjct: 2523 GTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYT- 2581
Query: 463 VYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPP-VPGKTSPHGGAMGAA 521
V T + P+G PLG T + + + RPP V +P G +
Sbjct: 2582 ------VATGNFHPSGSPLGPSSGSTGESYGL------SPLRPPSVLPPPAPDGSLPYLS 2629
Query: 522 AGVLHHRGCLASPHSLPDPTVG 543
G G + DP G
Sbjct: 2630 HGASQRSGITSPVEKREDPGTG 2651
Score = 54.3 bits (129), Expect = 5e-07
Identities = 81/328 (24%), Positives = 106/328 (32%), Gaps = 77/328 (23%)
Query: 139 PSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTR 198
P + P PE ES PP+ R SP E P P P L L R
Sbjct: 442 PPPEESPLSPPPE--ESPTSPPPEASRLSPPP-------EELPASPLPEA--LHLSRPLE 490
Query: 199 GSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESE 258
S ++ P+ E P+ P P + S EES
Sbjct: 491 ESPLSPPPE----ESPL---------------------------SPPPESSPFSPLEESP 519
Query: 259 AIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALP-SRRDGTPTK 317
E P P A E + PP + SPP + L P P S P + R P +
Sbjct: 520 LSPPEESPPSP--ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 318 TTPCEIPP------PFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTP 371
+P PP P P + PP P + +P +S P P +P
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESP---LSPPPEASRLSPPPEDSP 634
Query: 372 APQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMI 431
P E P PPP + L +PLP P P S +
Sbjct: 635 MSPPP----EESPMSPPPEVSRL-------------SPLPVVSRLSP------PPEESPL 671
Query: 432 CPKAAGAPAAPPAPAALLPGPPKDKAVS 459
P +P +PP A+ L PP+D S
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTS 699
Score = 47.8 bits (112), Expect = 4e-05
Identities = 93/405 (22%), Positives = 138/405 (34%), Gaps = 78/405 (19%)
Query: 107 EDSSTRRPPAKPRRHPSTKLSMVGPG---SGAETPPSKKAGSQKP-----TPEGRESSRK 158
E+S PP R P +S + P S PP + S P +P +S
Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699
Query: 159 VPPQKPRRSP---NTQLSVSFDES-----------CPPG------PSPRGGNL-PLQRLT 197
PP+ SP ++ +S+ +ES CP P P +L P
Sbjct: 700 PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759
Query: 198 RGSRVAGDPDVGAQ-EEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEE 256
S A +P + Q EEP + + G L+ P +EE
Sbjct: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQP-------EELHLSPQTEE 812
Query: 257 ---SEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDG 313
S E P PEE+ + P L+ P++ H L P + P S P +
Sbjct: 813 PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR--PEESH-LSPELEKPPLSPRPEK--- 866
Query: 314 TPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAP 373
P + C P P P L+ + A PG+ P L E +P+
Sbjct: 867 PPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE-----PPLSPLPEELPLSPSG 921
Query: 374 QVPARERETPPPPPPPPAANLLL------LGPSGR------ARSHS------------TP 409
+ + PP P PPP + ++ L P G A+ S TP
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP 981
Query: 410 LPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPK 454
+ P +P MI P + G+P P +P + P PP+
Sbjct: 982 ISPPPEANCTDPEPVP---PMILPPSPGSPVGPASPILMEPLPPQ 1023
Score = 46.2 bits (108), Expect = 1e-04
Identities = 76/340 (22%), Positives = 104/340 (30%), Gaps = 52/340 (15%)
Query: 107 EDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKP--------------TPEG 152
E+S PP + P + S + P PP + S P +P
Sbjct: 445 EESPLSPPPEESPTSPPPEASRLSP------PPEELPASPLPEALHLSRPLEESPLSPPP 498
Query: 153 RESSRKVPPQKPRRSPNTQLSVSFDESCPPGP------SPRGGNLPLQRLTRGSRVAGDP 206
ES PP+ SP + +S E PP P SP PL S ++ P
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558
Query: 207 DVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGG-GPTPPAGADSDSEESEAIYEEMK 265
+ P L+ PP P P S E+ ++ +
Sbjct: 559 EELPTSPPP--------------EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604
Query: 266 Y-PLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIP 324
PL E + PP + SPP + + P P S P +P P
Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664
Query: 325 PPFPNLLQHRP---PLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERE 381
PP + L P P P+A S P D + P P +P E
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724
Query: 382 TPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGE 421
P P P L P H +P P + PR E
Sbjct: 725 LLPLPEEPQ------LCPRSEG-PHLSPRPEEPHLSPRPE 757
Score = 46.2 bits (108), Expect = 1e-04
Identities = 84/324 (25%), Positives = 111/324 (34%), Gaps = 49/324 (15%)
Query: 154 ESSRKVPPQKPRRSPNTQLS-VSFDESCPPG----PSPRGGNLPLQRLTRGSRVAGDPDV 208
+ S+ V P + P TQ S + C P P P+ G PLQ L G R G P +
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTG--PLQELGAGPRPQGPPRL 4289
Query: 209 GAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPL 268
A G GP LG PTPP + + + + P
Sbjct: 4290 PAPP------------------GALSTGPVLGPVHPTPPPSSPQEPKRPSQL------PS 4325
Query: 269 PEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFP 328
P A PP T PQ P PP PA+A D +K PP
Sbjct: 4326 PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAA--QLADTLFSKGLGPWDPP--D 4381
Query: 329 NLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPA--PQVPARERETPPPP 386
NL + + P + + G V L +EP A Q RE P
Sbjct: 4382 NLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIG 4441
Query: 387 PPPPAANLLLLGPSGRA---------RSHSTPLPP-QGSGQPRGE--RELPNSHSMICPK 434
P + +LLL GP A R+ + L +GS R E + + + + K
Sbjct: 4442 APGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQK 4501
Query: 435 AAGAPAAPPAPAALLPGPPKDKAV 458
G P+ AA P PK K V
Sbjct: 4502 LQGTPSNKEDAAARKPLTPKPKRV 4525
Score = 45.4 bits (106), Expect = 2e-04
Identities = 77/287 (26%), Positives = 95/287 (33%), Gaps = 56/287 (19%)
Query: 235 AGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHA 294
A P + G PT PAG S S + P P+ GE PP + A P Q P
Sbjct: 2120 AAPTIFIGSPTTPAGL-STSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFG 2178
Query: 295 L-----------------PPH--------------AHRRPASALPSRRDGTPTKTTPCEI 323
L PP+ A RP + P TP T +
Sbjct: 2179 LAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQP 2238
Query: 324 PPPFPNLLQHRPPL--LAFPQAKSASRTPGDGVSRLPVLCHSKEPAG-STPAPQVPARER 380
P P L P L LA P++ G G + P+L S P G S A +V E
Sbjct: 2239 STPDPFLKPRCPSLDNLAVPESPGV----GGGKASEPLL--SPPPFGESRKALEVKKEEL 2292
Query: 381 ETPPPPPPPPAANLLLLGPSGR---ARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAG 437
P PP + SG TP + PR + P S P
Sbjct: 2293 GASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQS-----PGLGL 2347
Query: 438 APAAPPAPAALLPGPPKDKAV----SYTMVYSAVKVTTHSVLPAGPP 480
P PP AL P PP + SYT Y+ +T P PP
Sbjct: 2348 RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPR---PQPPP 2391
Score = 36.2 bits (82), Expect = 0.13
Identities = 28/104 (26%), Positives = 36/104 (34%), Gaps = 9/104 (8%)
Query: 88 VGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQK 147
+G +GG PG +G L E + RP PR GP G P + Q+
Sbjct: 4257 LGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE 4316
Query: 148 PTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNL 191
P K P Q P S + P P P+G L
Sbjct: 4317 P---------KRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL 4351
Score = 35.8 bits (81), Expect = 0.17
Identities = 49/193 (25%), Positives = 70/193 (36%), Gaps = 26/193 (13%)
Query: 276 RANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRP 335
R P L PPQ P P +A P+ G+PT TP + L +P
Sbjct: 2095 RKTDRPALHLRIPPQ-----PGALGSPPPAAAPTIFIGSPT--TPAGLSTSADGFL--KP 2145
Query: 336 PLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPA---- 391
P + P S ++P S++P G PA + R PP PP P+
Sbjct: 2146 PAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGA 2205
Query: 392 -ANLLLLGPSGR------ARSHSTPLPPQGSGQPRG-----ERELPNSHSMICPKAAGAP 439
A +LG S R H+TP P QP + P+ ++ P++ G
Sbjct: 2206 PAQPPMLGASSRPGAGQPGEFHTTP-PGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG 2264
Query: 440 AAPPAPAALLPGP 452
+ L P P
Sbjct: 2265 GGKASEPLLSPPP 2277
Score = 33.5 bits (75), Expect = 0.85
Identities = 39/164 (23%), Positives = 62/164 (37%), Gaps = 25/164 (15%)
Query: 355 SRLPVLCHSKEPAGSTPAPQVPA-------------RERETPPPPPPPPAANLLLLGPSG 401
S+L +L K+ +PAP+ P R+ PPP P P + L P+
Sbjct: 4871 SQLDILSLLKQ---ESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPAS 4927
Query: 402 RARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYT 461
LP +P E +P+ P A+ +A P P A P +D
Sbjct: 4928 PPTEPLVELPT----EPLAEPPVPSP----LPLASSPESARPKPRARPPEEGEDSRPPRL 4979
Query: 462 MVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRP 505
+ V+ +L G+G + E+E++ L T+ RP
Sbjct: 4980 KKWKGVRWKRLRLL-LTIQKGSGRQEDEREVAEFMEQLGTALRP 5022
Score = 33.1 bits (74), Expect = 1.1
Identities = 60/259 (23%), Positives = 85/259 (32%), Gaps = 47/259 (18%)
Query: 324 PPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETP 383
P P P+ LQ +PPL R PG ++ +L AG Q+ +
Sbjct: 4082 PQPQPSSLQLQPPL----------RLPGQQQQQVSLL----HTAGGGSHGQLGSGSSSEA 4127
Query: 384 PPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPP 443
P A + LG + + + L PQ QP ER + N+ PP
Sbjct: 4128 SSVPHLLAQPSVSLGDQPGSMTQNL-LGPQ---QPMLERPMQNNTG----------PQPP 4173
Query: 444 APAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVL------HG 497
P +L V ++ VL P L P+ ++++ L
Sbjct: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
Query: 498 MLCTSSRPPV--PG-KTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPAT 554
PP PG +TSP G +G C P P GPL L P
Sbjct: 4234 SQAVRQTPPYQEPGTQTSPLQGLLG----------CQPQLGGFPGPQTGPLQELGAGPRP 4283
Query: 555 AAGLKRPPAYESLKAGGVL 573
+ P +L G VL
Sbjct: 4284 QGPPRLPAPPGALSTGPVL 4302
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 65.5 bits (158), Expect = 2e-10
Identities = 123/458 (26%), Positives = 159/458 (34%), Gaps = 83/458 (18%)
Query: 11 EWRQHKEEE---AKRSSSKEVAPAGSAGPAA----GQGPGVRVRDIASLRR--------- 54
EW E ++R KE P P A G G G V I+++ R
Sbjct: 1320 EWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKD 1379
Query: 55 -SLRMGFMTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSST-- 111
S R P + P A S S G GGGPGG +G D +
Sbjct: 1380 LSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGG-----GGGPGGRTGPGRGDKRSWP 1434
Query: 112 -----RRPPAKPRRHPSTKLSMVGPGSGA-----ETPPSKKAGSQKPTPE--GRESSRKV 159
RPP + R P L P S A + S AG Q+ + R+ S
Sbjct: 1435 SPKNRSRPPEE--RPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTA 1492
Query: 160 PPQKPRRSPNTQLSVSFDESCPPGPSPRGGN-LPLQRLTRGSRVAGDPDVGAQEEPVYIE 218
P PR P P GPSPR QR+ G ++ DP EEP
Sbjct: 1493 PGGHPRHKPGLP-------QAPQGPSPRPPTRYEPQRVNSG--LSSDPHF---EEP---- 1536
Query: 219 MVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAG--EGR 276
G + RG G + AG P PP + + E + EE P P +G +
Sbjct: 1537 --GPMVRGVGGTPRDSAGV-----SPFPPKRRERPPRKPELLQEE-SLPPPHSSGFLGSK 1588
Query: 277 ANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIP-PPFPNLL---- 331
GP P A S AL PH R +A SR+ P+ P P PF ++
Sbjct: 1589 PEGPGP-QAESRDTGTEALTPHIWNRLHTAT-SRKSYRPSSMEPWMEPLSPFEDVAGTEM 1646
Query: 332 ---QHRPPLLAFPQAKS---ASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPAR-ERETPP 384
L Q S + R+ DG + K P GS+P VP + P
Sbjct: 1647 SQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEP 1706
Query: 385 PPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGER 422
P PPPA + + PLPP G R +R
Sbjct: 1707 PRRPPPAPH----DGDRKELPREQPLPPGPIGTERSQR 1740
Score = 53.5 bits (127), Expect = 8e-07
Identities = 108/459 (23%), Positives = 147/459 (32%), Gaps = 94/459 (20%)
Query: 64 PASQEHTPH--PCRSAMAPRSLSCHSVG-----SMDSVGGGPGGASGGLTEDSSTR---- 112
P + TP P A AP + S + G ++ S GG S G E S
Sbjct: 535 PPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLP 594
Query: 113 -----RPPAK---PRRHPSTKLSMVGPGSG-AETPPSKKAGSQK------PTPEGRESSR 157
PP + P P K+ G G G PPS+ G K P + ++ +
Sbjct: 595 SKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQ 654
Query: 158 KVPPQKPRRSPNTQLSVSFDESCPPGP----------SPRGGNLPLQRLTRGS--RVAGD 205
+ Q+ + Q + PP P +P+ P + L G+ R
Sbjct: 655 LLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPM 714
Query: 206 PDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMK 265
P + + I D GR P + G P +DS SE
Sbjct: 715 PPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAP 774
Query: 266 YPLPEEAGEGRANGPPPLTA---------TSPPQQPHALPPHAHRRPASALPSRRDGTPT 316
L R G PP+ T+ P +P L + R TP
Sbjct: 775 AML-------RERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPP 827
Query: 317 KTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVP 376
+PPP PP LA + PG +SR P+ E G P P P
Sbjct: 828 ------VPPP--------PPYLASYPGFPENGAPGPPISRFPL-----EEPGPRPLPWPP 868
Query: 377 ARER----ETPPPPPPPPAANLL-LLGP-SGRARSHSTPLPPQGSGQPRGE--------- 421
+ +TPPP PP L GP +GR + QG PR E
Sbjct: 869 GSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGP 928
Query: 422 ------RELPNSHSMICPKAAGAPAAPPAPAALLPGPPK 454
R +P P+ AG PP P + PPK
Sbjct: 929 RPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPK 967
Score = 53.1 bits (126), Expect = 1e-06
Identities = 49/173 (28%), Positives = 64/173 (36%), Gaps = 36/173 (20%)
Query: 265 KYPLPEEAGEGRANGPP--PLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCE 322
K+ P++ + PP P T PP P LP PASA PT T E
Sbjct: 496 KFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASA--------PTPETEPE 547
Query: 323 IPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPA---------P 373
P QA A TP GV+ P L ST + P
Sbjct: 548 EP----------------AQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEP 591
Query: 374 QVPARERETPPPP-PPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELP 425
Q+P++E PP PPP + + P G + P QG G P+ ++ LP
Sbjct: 592 QLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLP 644
Score = 50.4 bits (119), Expect = 7e-06
Identities = 92/368 (25%), Positives = 121/368 (32%), Gaps = 40/368 (10%)
Query: 108 DSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGR-ESSRKVPPQKPRR 166
D + PA P PST PP+ S PTPE E + PP +
Sbjct: 501 DKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPAS-APTPETEPEEPAQAPPAQSTP 559
Query: 167 SPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRG 226
+P + + S G+ + P+ + P V V
Sbjct: 560 TPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPK 619
Query: 227 GGRSGGGLAGPPLGGGGP-----TPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPP 281
G G P G G P PP ++ E + ++ + ++ +G A PP
Sbjct: 620 GDGIGPTRQPPSQGLGYPKYQKSLPPR---FQRQQQEQLLKQQQQHQWQQHQQGSA--PP 674
Query: 282 PLTATSPPQQP--HALP-PHAHRRPASALPSRRDGTPTKTTPCEIPPPF--------PNL 330
SPPQ A+P P A P AL G P P P + P L
Sbjct: 675 TPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRL 734
Query: 331 LQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAP---QVPA--RERETPPP 385
LQ RPPL +P PG S L V + GS+ P PA RER TPP
Sbjct: 735 LQGRPPLDFYP--------PGVHPSGL-VPRERSDSGGSSSEPFDRHAPAMLRERGTPPV 785
Query: 386 PPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAP 445
P + R ++PL +G R P A P P
Sbjct: 786 DPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENG 845
Query: 446 AALLPGPP 453
A PGPP
Sbjct: 846 A---PGPP 850
Score = 43.5 bits (101), Expect = 8e-04
Identities = 71/300 (23%), Positives = 93/300 (31%), Gaps = 59/300 (19%)
Query: 249 GADSDSEESEAIYEEMKYP---LPEEAGEGRANGP----------------PPLTATSPP 289
G DSD E +E + P EA + N P PP T PP
Sbjct: 347 GRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPP 406
Query: 290 QQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPN-------------------- 329
LPP HR PA D PC+ P P
Sbjct: 407 APKPPLPP-PHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVE 465
Query: 330 -----------LLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPAR 378
+Q + K G RL + A STPAP PA
Sbjct: 466 RARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPP-PAV 524
Query: 379 ERETPPPPPPPPAA----NLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPK 434
+E P PP PPPA+ P+ + STP P + P ++ S
Sbjct: 525 PKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAA-PTLVSGGGSTSSTSSGS 583
Query: 435 AAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPA--GPPLGAGEPKTEKEI 492
+P P P+ P PP++ T V+ + P P G G PK +K +
Sbjct: 584 FEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSL 643
Score = 43.1 bits (100), Expect = 0.001
Identities = 88/325 (27%), Positives = 112/325 (34%), Gaps = 62/325 (19%)
Query: 95 GGGPGGASGGLTEDSSTRRPPAKPRRH-------PSTKLSMVGPG---SGAETPPSKKAG 144
G PG + G+ + P A PRR P TK+ + P G ETP K
Sbjct: 927 GPRPGSSRRGIPPEE----PGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPD 982
Query: 145 SQKPTPEGRESSRKVPPQKPRRSPNTQL--SVSFDESCPPGPSPRGGN--LPLQRLTRGS 200
K T +G+ K P SP +L S++ P RG R RG+
Sbjct: 983 PLKIT-KGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGT 1041
Query: 201 RVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAI 260
++E Y E GD RGGG GG PP P +++ SE SE
Sbjct: 1042 YGGRGRGARSREFRSYREFRGDDGRGGGT--GGPNHPP----APRGRTASETRSEGSE-- 1093
Query: 261 YEEMKYPLPEEAGEG--------------RANGPPPLTATSPPQQPHALPPHAHRRPASA 306
YEE+ + E A P T T P P PP A PA A
Sbjct: 1094 YEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPP--PPGAPPSPAPA 1151
Query: 307 LPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLA---FPQAKSASRTPGDGVSRLPVLCHS 363
+ R G TP +P PP + P AKS L
Sbjct: 1152 RFTARGGRVF--TPRGVPSRRGRGGGRPPPQVCPGWSPPAKS--------------LAPK 1195
Query: 364 KEPAGSTPAPQVPARERETPPPPPP 388
K P G P + P +E+ P P P
Sbjct: 1196 KPPTGPLPPSKEPLKEKLIPGPLSP 1220
Score = 43.1 bits (100), Expect = 0.001
Identities = 116/508 (22%), Positives = 165/508 (32%), Gaps = 128/508 (25%)
Query: 95 GGGPGGASGGLTEDSSTRR-------PPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQK 147
GG GG++ G+ + RR KP R K G+E PS +
Sbjct: 1224 GGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASA 1283
Query: 148 PTPEGRESSRKVPPQKPRRSPNTQLSVS-------------------------FDESCPP 182
P PE ++ V P PRR+ +S D+ PP
Sbjct: 1284 PGPEEALTTVTVAP-APRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPP 1342
Query: 183 GP--SPR---------GGNLP-LQRLTRGSRVAGDPDV----------GAQEEPVYIEMV 220
+P+ GG +P + ++RG D+ G + +
Sbjct: 1343 PVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPG 1402
Query: 221 GDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGP 280
G G SGGG GP GG T P D S +P P+ P
Sbjct: 1403 GKAGSSGSSSGGGGGGP----GGRTGPGRGDKRS-----------WPSPKNRSRPPEERP 1447
Query: 281 PPLTATSPPQQPHA---LPPHAHRRPAS-----ALPSRRDGTPTKTTPCEIPPPFPNLLQ 332
P L PP A L H PA A S R G+ T P P +
Sbjct: 1448 PGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVT------APGGHP---R 1498
Query: 333 HRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAA 392
H+P L PQ S R P + S +P P P V
Sbjct: 1499 HKPGLPQAPQGPS-PRPPTRYEPQRVNSGLSSDPHFEEPGPMVRG--------------- 1542
Query: 393 NLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGP 452
+G + R + +P PP+ +P + EL S+ P ++G + P PGP
Sbjct: 1543 ----VGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEG----PGP 1594
Query: 453 PKDKAVSYT-----MVYSAVKVTT-------HSVLPAGPPLGAGEPKTEKEISVLHGMLC 500
+ + T +++ + T S+ P PL E E+S +
Sbjct: 1595 QAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD 1654
Query: 501 TS-----SRPPVPGKTSPHGGAMGAAAG 523
S S P ++SP GG GAA G
Sbjct: 1655 LSGDSQVSSGPCSQRSSPDGGLKGAAEG 1682
Score = 34.7 bits (78), Expect = 0.38
Identities = 31/98 (31%), Positives = 40/98 (40%), Gaps = 10/98 (10%)
Query: 321 CEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARER 380
C P P +LLQ R L + S PG LP S PA P V ++
Sbjct: 1934 CPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLP----SGAPAQQMLLPMVDSQLP 1989
Query: 381 ET------PPPPPPPPAANLLLLGPSGRARSHSTPLPP 412
P PPP PP +LL +GP+ + S + PP
Sbjct: 1990 VVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPP 2027
Score = 33.1 bits (74), Expect = 1.1
Identities = 82/348 (23%), Positives = 105/348 (30%), Gaps = 53/348 (15%)
Query: 97 GPGGASGGLTEDSSTRRPPAKPRRHPSTKLS------------MVGPGSGAETPPSKKAG 144
GP G D T P +P P + +VG AE +
Sbjct: 1731 GPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVT 1790
Query: 145 SQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAG 204
P E +S N C P PS G L + GS
Sbjct: 1791 EAIPVSRDWELLPSAAASAEPQSKNLDSG-----HCVPEPSSSGQRL-YPEVFYGSAGPS 1844
Query: 205 DPDV--GAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLG-GGGPTPPAGADSDSEESEAIY 261
+ GA + ++ G FR G S PL GP PP+ S + +
Sbjct: 1845 SSQISGGAMDSQLHPNSGG--FRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLA-LKGQF 1901
Query: 262 EEMKYPLPEEAGEGRANG---PPPLTATSPPQQPHALPPHAHRRPASALPSRRDGTPTKT 318
+ E G+ A G PPP SP P LP + + LPS D T
Sbjct: 1902 LDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPL 1961
Query: 319 TPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQ---- 374
P P+ + LL S+LPV+ P PAP
Sbjct: 1962 QPGGQSGFLPSGAPAQQMLLPMVD------------SQLPVVNFGSLPPAPPPAPPPLSL 2009
Query: 375 VPARERETPPP----PPPPPAANLL------LLGPSGRARSHSTPLPP 412
+P PP PPP PA +L GRA H L P
Sbjct: 2010 LPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAELHPVELKP 2057
Score = 31.2 bits (69), Expect = 4.2
Identities = 54/208 (25%), Positives = 79/208 (37%), Gaps = 34/208 (16%)
Query: 246 PPAGADSDSEESEAIYEEMKYPLPEEAGEGRAN----GPPPLTATSPPQQPHALPPHAHR 301
PPA S E++ + L + G G A+ P + S Q P + P A +
Sbjct: 58 PPANLPSLKAENKG--NDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQ 115
Query: 302 RPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLC 361
PAS P R P T P P+ ++ ++ QA GDG +L
Sbjct: 116 TPASNQPKRPPAAPENT------PLVPSGVK------SWAQASVTHGAHGDGGRASSLLS 163
Query: 362 H-SKEPAGSTPA---PQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQ 417
S+E + A A+ERE+ P GPS R ++ +T G G+
Sbjct: 164 RFSREEFPTLQAAGDQDKAAKERESAEQSSGP--------GPSLRPQNSTT--WRDGGGR 213
Query: 418 PRGERELPNS--HSMICPKAAGAPAAPP 443
E E P+S H P+ P+ PP
Sbjct: 214 GPDELEGPDSKLHHGHDPRGGLQPSGPP 241
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 64.3 bits (155), Expect = 4e-10
Identities = 113/450 (25%), Positives = 152/450 (33%), Gaps = 69/450 (15%)
Query: 153 RESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQ-RLTRGSRVAGDPDVGAQ 211
R + PP P+RS + S + + P P G L ++ + R S +AG D G+
Sbjct: 939 RPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSA 998
Query: 212 EEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEE 271
++ + + GGG A G PT P A + + +K+ E
Sbjct: 999 GS---VKSIAAMLELSSIGGGGRAARRPPEGHPT-PRPASPEPGRVATVLASVKH--KEA 1052
Query: 272 AGEGRANGPPPLTATSPPQQPHALPPHAHRRPASALPSRRDGT-------PTKTTPCEIP 324
G G T + P A A P DGT P+K
Sbjct: 1053 IGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEG 1112
Query: 325 PPFPNLLQHRPPLLAFPQAKSASR-------TPGDGVSRLPVLCHSKEPAGSTPAPQV-- 375
PP ++ L +AK + T D V R P + AG P P +
Sbjct: 1113 PPLAK-VEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKA--KEREAGPEPPPPLSV 1169
Query: 376 -----------PARERETPP--PPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGER 422
PA E+ PP PPPPPPA P +H PLPP G+ R
Sbjct: 1170 YHNGTGTVRRRPASEQAGPPELPPPPPPAE------PPPTDLAHLPPLPPP-EGEARKPA 1222
Query: 423 ELPNSHSMI----CPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAG 478
+ P S + PK G+P P + LPGP + T V P
Sbjct: 1223 KPPVSPKPVLTQPVPKLQGSP-TPTSKKVPLPGPGSPEV-------KRAHGTPPPVSPKP 1274
Query: 479 PPLGAGEPKTEKEISVLHGMLCTSSRP-PVPGKTSPHGGAMGAAAGVLHHRGCLASPHSL 537
PP P K + + G+ S+ P P P A+ G G ASP
Sbjct: 1275 PP----PPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLG--ASPAKP 1328
Query: 538 PDPTVG----PLTPLWTYPATAAGLKRPPA 563
P P P P A AA PPA
Sbjct: 1329 PSPGAPALHVPAKPPRAAAAAAAAAAAPPA 1358
Score = 63.2 bits (152), Expect = 1e-09
Identities = 104/393 (26%), Positives = 137/393 (34%), Gaps = 72/393 (18%)
Query: 125 KLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGP 184
+LS +G G A P PEG + R P+ P R SV E+ PG
Sbjct: 1009 ELSSIGGGGRAARRP----------PEGHPTPRPASPE-PGRVATVLASVKHKEAIGPG- 1056
Query: 185 SPRGGNLPLQRLTRGSRVAG-------DPDVGAQEEPVYIEMVGDVF-RGGGRSGGGLAG 236
G + +R T V G P A P + G RG + G+ G
Sbjct: 1057 ----GEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEG 1112
Query: 237 PPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPE--------EAGEGRANGPPPLTATSP 288
PPL + +++++ E +K+ L E +A E A PP P
Sbjct: 1113 PPLAKVEASATLKRRIRAKQNQQ--ENVKFILTESDTVKRRPKAKEREAGPEPP----PP 1166
Query: 289 PQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASR 348
H RRPAS + G P P P P L H PPL P + +R
Sbjct: 1167 LSVYHNGTGTVRRRPAS----EQAGPPELPPPPPPAEPPPTDLAHLPPL---PPPEGEAR 1219
Query: 349 TPGDG-VSRLPVLCHSKEPAGSTPAP---QVPA---------RERETPPP----PPPPPA 391
P VS PVL +P P +VP R TPPP PPPPP
Sbjct: 1220 KPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPT 1279
Query: 392 ANLLLLGPSGRARSHSTPLP-PQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLP 450
A + +G + P P P + QP P + P +P APA +P
Sbjct: 1280 APKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVP 1339
Query: 451 GPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGA 483
P A + +A P PP GA
Sbjct: 1340 AKPPRAAAAAAAAAAA---------PPAPPEGA 1363
Score = 41.6 bits (96), Expect = 0.003
Identities = 88/396 (22%), Positives = 121/396 (30%), Gaps = 115/396 (29%)
Query: 54 RSLRMGFMTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRR 113
+SL + + P E TP C+S + + GP G TE S+
Sbjct: 624 QSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEV-GPTTEKPSSHL 682
Query: 114 PPAKPR-------------RHPSTKLSMVGPGSGAETPPSKKAGS----QKPTPEGRESS 156
PP PR RH S+ ++G G + P ++ + P P
Sbjct: 683 PPT-PRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPG----- 736
Query: 157 RKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVY 216
PP++ R P S PP P P Q L G+ P + P
Sbjct: 737 --TPPREAR--PGRHGHSIKRASVPPVPGK-----PRQVLPPGTSHFTPPQTPTKTRP-- 785
Query: 217 IEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGR 276
G P GGP PA A + + +
Sbjct: 786 -------------------GSPQALGGPHGPAPATAKVKPT------------------- 807
Query: 277 ANGPPPLTATSPPQQPHALPPH-AHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRP 335
P L T P P +LP HR A LP +G P PPP P + P
Sbjct: 808 ---PQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAV---P 861
Query: 336 PLLAFPQAKS------------------------------ASRTPGDGVSRLPVLCHS-K 364
L P+A + A+ P V R HS +
Sbjct: 862 TLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVR 921
Query: 365 EPAGSTP----APQVPARERETPPPPPPPPAANLLL 396
PAG+ + R R+ PPPPPP ++ L
Sbjct: 922 APAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSAL 957
Score = 40.0 bits (92), Expect = 0.009
Identities = 48/185 (25%), Positives = 64/185 (34%), Gaps = 21/185 (11%)
Query: 113 RPPAKPRRHPSTKLSMVGPG-SGAETPPSKKAGSQKP-TPEGRESSRKVPP--QKPRRSP 168
R PAKP P L+ P G+ TP SKK P +PE + + PP KP P
Sbjct: 1219 RKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPP 1278
Query: 169 NTQLSVSFDESCP-----PGPSPRGGNLPLQRLTR--------GSRVAGDPDVGAQEEPV 215
V P P P+P P L + G+ A P GA
Sbjct: 1279 TAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPA--- 1335
Query: 216 YIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEG 275
+ + R + A PP G +P A EE+ A + E+ +
Sbjct: 1336 -LHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQE 1394
Query: 276 RANGP 280
A GP
Sbjct: 1395 DAQGP 1399
Score = 38.5 bits (88), Expect = 0.026
Identities = 76/330 (23%), Positives = 106/330 (32%), Gaps = 102/330 (30%)
Query: 165 RRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVA--------GDPDVGAQEE--- 213
R++P + ++ + PP P+P P + S ++ G +VG E
Sbjct: 620 RKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPS 679
Query: 214 ----PVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLP 269
P GGR+ + L G GP P+ S S+E Y L
Sbjct: 680 SHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQE---------YLLD 730
Query: 270 EEAGEGRANGPPPLTATSPPQQPHALP----PHAHRRPASALPSRRDG-----TPTKTTP 320
E G A G PP A P + H++ P +P LP TPTKT P
Sbjct: 731 E----GPAPGTPPREAR-PGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRP 785
Query: 321 CEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARER 380
PQA P +++ P PQ+
Sbjct: 786 ------------------GSPQALGGPHGPAPATAKVK------------PTPQLL---- 811
Query: 381 ETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPA 440
PP P + L P+ R ++ P P +G P AA PA
Sbjct: 812 ---PPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGP----------------AAPGPA 852
Query: 441 APPAPAAL-----------LPGPPKDKAVS 459
PP P A+ PG PK +A S
Sbjct: 853 PPPVPTAVPTLCLPPEADAEPGRPKKRAHS 882
Score = 36.6 bits (83), Expect = 0.100
Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 16/108 (14%)
Query: 93 SVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEG 152
+V G P G++G S R+PPA + P TPPS A KP G
Sbjct: 1286 AVAGLPSGSAGPSPAPSPARQPPAALAKPPG-------------TPPSLGASPAKPPSPG 1332
Query: 153 RESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGS 200
+ VP + PR + + + + P G SP G+ Q+L S
Sbjct: 1333 APALH-VPAKPPRAAAAAAAAAAAPPAPPEGASP--GDSARQKLEETS 1377
Score = 34.3 bits (77), Expect = 0.50
Identities = 45/183 (24%), Positives = 61/183 (33%), Gaps = 24/183 (13%)
Query: 365 EPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGEREL 424
+ A + PA P E+ + PP P A GRAR S+ G G P +
Sbjct: 662 QAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPM 721
Query: 425 PNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAG 484
S + + AP PP A PG HS+ A P G
Sbjct: 722 SRSQEYLLDEGP-APGTPPREAR--PGR-----------------HGHSIKRASVPPVPG 761
Query: 485 EPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGP 544
+P+ H + PG GG G A + +P LP PT P
Sbjct: 762 KPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVK---PTPQLLP-PTERP 817
Query: 545 LTP 547
++P
Sbjct: 818 MSP 820
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 63.2 bits (152), Expect = 1e-09
Identities = 153/670 (22%), Positives = 205/670 (30%), Gaps = 140/670 (20%)
Query: 92 DSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPE 151
+ GGG GG S + + PP+ PS + P A + + G+
Sbjct: 1186 EPTGGGGGGGSSPSPAPAMSPVPPS-----PSPVPTPASPSGPATLDFTSQFGAALVGAA 1240
Query: 152 GRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQ 211
RE + + RR LS + G P RL + D + +
Sbjct: 1241 RREGGWQ---NEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSI--DEGMFSA 1295
Query: 212 EEPVYIEMVGDVFRGGGRSGGGLAGPPLGGGG----------------PTPPAGADSDSE 255
E + +E G G G G G GGGG P D S
Sbjct: 1296 EPYLRLESAGS---GAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASP 1352
Query: 256 ESEAIYEEMKYPLPEEAGEGRANGPPPLTAT----SPPQQPHALPPHAHRRPASAL---- 307
A+ + L E + G A PPP + +PP PH PHAH P L
Sbjct: 1353 LGLALAARER-ALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGAS 1411
Query: 308 ---PSRRD-------GTPTKTTPCEIPPPFPNLLQHRPPLL-----AFPQAKSASRTPGD 352
P+RR+ G+ K+ P P +LL PP Q + P
Sbjct: 1412 PPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHP 1471
Query: 353 GVS--------------------------RLPVLCHSKEPAGSTPAPQVPARERETPPPP 386
GVS R PV P+ P P+ R PP P
Sbjct: 1472 GVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSP 1531
Query: 387 PPPPAAN-----LLLLGPSGRARS-------HSTPLPP-----QGSGQPRGERELPNSHS 429
P A+ LL+L P + PLPP +P H
Sbjct: 1532 TSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHP 1591
Query: 430 MICPKAAGAPAAPPAPAALLPGPP--KDKAVSYTMVYSAVKVTTHSVL-------PAGPP 480
+ A P P P A+ PP A S T S V T P GPP
Sbjct: 1592 LPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPP 1651
Query: 481 LGA-------------------GEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAA 521
A G + + S H + SS + ++ GG+ G
Sbjct: 1652 APAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGG 1711
Query: 522 AGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAY--------ESLKAGGVL 573
G +AS L D V L ++ G PP +L A G L
Sbjct: 1712 GGA---GAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGL 1768
Query: 574 NKGCGVGAPSPMV----KIQLQEQGTDG-GAFASISCAHVIASAGTPEEEEEEVGAATFG 628
G G P+ + + GTDG A + S AG P E EV
Sbjct: 1769 RPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLP 1828
Query: 629 AGWALQRKVL 638
+L RK+L
Sbjct: 1829 TASSLPRKLL 1838
Score = 46.2 bits (108), Expect = 1e-04
Identities = 115/512 (22%), Positives = 160/512 (31%), Gaps = 115/512 (22%)
Query: 114 PPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPT-PEGRESSRKVP-------PQKPR 165
P + R PS + PGSG P S A P+ P+ R SR+ P
Sbjct: 939 PSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHH 998
Query: 166 RSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFR 225
P+ + PP P + P G PD + P + +
Sbjct: 999 HPPHHH----HHHAPPPQPHHHHAHPP---HPPEMETGGSPD----DPPPRLALGPQPSL 1047
Query: 226 GGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTA 285
G R GGGP+P GA S S A G G + GP
Sbjct: 1048 RGWR-----------GGGPSPTPGAPSPSHHGSA-----------GGGGGSSQGPALRYF 1085
Query: 286 TSPPQQPHA---LPPHAHRRPASAL---------PSRRDGTPTKTTPCEIPPPFPNLLQH 333
PP+ A +P + R L P + G P +P P P
Sbjct: 1086 QLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQP----- 1140
Query: 334 RPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAAN 393
PP +A P K++ P + K P+ S+ E PP P P
Sbjct: 1141 -PPAVAAPSEKNSIPIPTIII---------KAPSTSSSGRSSQGSSTEAEPPTQPEPT-- 1188
Query: 394 LLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAAL----- 448
G G S +P P P P PA+P PA L
Sbjct: 1189 ----GGGGGGGSSPSPAPAMSPVPP-------------SPSPVPTPASPSGPATLDFTSQ 1231
Query: 449 ----------LPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGE-PKTEKEISVLHG 497
G +++A + ++ + G GA P+ S+ G
Sbjct: 1232 FGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEG 1291
Query: 498 MLCTSSRPPVPGKTSPHG---GAMGAAAGVLHHRGCLASPHSL--PDPTVGPLTPLWTYP 552
M S+ P + +++ G G GA + G ++ S P P V PLT P
Sbjct: 1292 MF--SAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDP 1349
Query: 553 ATAAGLKRPPAYESLKAGGVLNKGCGVGAPSP 584
A+ GL +LK G GAP P
Sbjct: 1350 ASPLGLALAARERALKESSE-----GGGAPQP 1376
Score = 40.8 bits (94), Expect = 0.005
Identities = 70/281 (24%), Positives = 90/281 (32%), Gaps = 39/281 (13%)
Query: 122 PSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRE-----SSRKVPPQKPRRSPNTQLSVSF 176
P+T L V P + A PP+ + + T E P P +
Sbjct: 1598 PATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPA 1657
Query: 177 DESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAG 236
+ PGP P G S + + + P+ GGG AG
Sbjct: 1658 PAAPQPGPDPPPGT--------DSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAG 1709
Query: 237 PPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPP--PLTATSPPQQPHA 294
GGGG AGA S E + + Y + G GPP P T + A
Sbjct: 1710 ---GGGG----AGAGVASGP-ELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRA 1761
Query: 295 LPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGV 354
L RP + R TPT T LL R + S P GV
Sbjct: 1762 LGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALR----------ACSGPPTAGV 1811
Query: 355 SRLPVLCHSKEP------AGSTPAPQVPARERETPPPPPPP 389
+ PV + P A S P +P E PPPPP P
Sbjct: 1812 AGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLP 1852
Score = 40.0 bits (92), Expect = 0.009
Identities = 93/364 (25%), Positives = 117/364 (32%), Gaps = 95/364 (26%)
Query: 138 PPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLT 197
PP+ K P S +PP P S PP PS G RLT
Sbjct: 903 PPAMKFSRSLSVP----GSEDIPPPPTTSPPEPPYST------PPVPSSSG------RLT 946
Query: 198 RGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGL-AGPPLGGGGPTPPAGADSDSEE 256
R G F G SGG L A P GP+PP E+
Sbjct: 947 PSPR-------------------GGPFNPG--SGGPLPASSPASFDGPSPPDTRVGSREK 985
Query: 257 SEAIYEEMKYPLPEEAGEGRANGPPPLTAT--SPPQQPHALPPHAHRRPASALPSRRDGT 314
S +Y PLP A+ PP +PP QPH H H P G+
Sbjct: 986 S--LYHSG--PLPP------AHHHPPHHHHHHAPPPQPH----HHHAHPPHPPEMETGGS 1031
Query: 315 PTKTTPCEIPPPFPNLLQHR-----PPLLAFPQAKSASRTPGDGVSRLPVLCHSK-EPAG 368
P P P P+L R P A + S G G S+ P L + + P
Sbjct: 1032 PDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRA 1091
Query: 369 STPAPQVPARE---------RET-------------PPPPPPPPAANLLLLGPSGRARSH 406
++ A VPAR ++T P P P PA+ + + +
Sbjct: 1092 ASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKN 1151
Query: 407 STPLP------PQGSGQPRG------ERELPNSHSMICPKAAGAPAAPPAPAALLPGPPK 454
S P+P P S R E E P G + PAP A+ P PP
Sbjct: 1152 SIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAP-AMSPVPPS 1210
Query: 455 DKAV 458
V
Sbjct: 1211 PSPV 1214
Score = 37.7 bits (86), Expect = 0.045
Identities = 98/417 (23%), Positives = 137/417 (32%), Gaps = 67/417 (16%)
Query: 66 SQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLT-----------------ED 108
S+ + HP + + +LS S S GGG G +G +
Sbjct: 1680 SRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGG 1739
Query: 109 SSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEG--RESSRKVPPQKPRR 166
SST PP P+ +KL G GA +G +P P G R+ P
Sbjct: 1740 SSTPGPPYPPQLMTPSKLR--GRALGA-------SGGLRPGPSGGLRDPVTPTSPTVSVT 1790
Query: 167 SPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRG 226
T ++ +C GP G G VA +P+V P + +
Sbjct: 1791 GAGTDGLLAL-RAC-SGPPTAG--------VAGGPVAVEPEVPPVPLPTASSLPRKLL-- 1838
Query: 227 GGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTAT 286
G G PPL G P A A + + S I E+ L + G A G P
Sbjct: 1839 PWEEGPGPPPPPLPGPLAQPQASALATVKAS--IISELSSKLQQFGGSSAAGGALPWA-- 1894
Query: 287 SPPQQPHALPPHAHRRPASALPSR-----RDGTPTKTTPCEIPPPFPNLLQH--RPPLLA 339
+ +H AS +P R R + + P +L Q+ +PPL
Sbjct: 1895 ---RGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPP 1951
Query: 340 FPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPP----PPPPPAANLL 395
P S T + P + ST + E E PP P P
Sbjct: 1952 LPTGTGVSPT----AAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPAS 2007
Query: 396 LLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGP 452
S R S P+ P G P G ++ S + AG A P AP + P P
Sbjct: 2008 EHKVSPAPRPSSLPILPSGPLYP-GLFDIRGSPT----GGAGGSADPFAPVFVPPHP 2059
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 62.4 bits (150), Expect = 2e-09
Identities = 118/438 (26%), Positives = 148/438 (33%), Gaps = 91/438 (20%)
Query: 63 MPASQEHTPHPCRSAMA---PRSLSCHSVGSMDSVGGGPGG----ASGGLTEDSSTRRPP 115
+P E P C S P + + GS S GP A L +T P
Sbjct: 650 LPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDP 709
Query: 116 AKPRRHPSTKLSMVGPGSG-----AETPPSKKAGSQKPTPE--GRES----SRKVPPQKP 164
+P+R S LS GP G AE P GS GR + S V P
Sbjct: 710 PRPKRR-SHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA 768
Query: 165 RRSPNTQ-LSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDV 223
R +P +Q ++ PP P P+ R S V+G + E P E G
Sbjct: 769 RGTPRSQSFALRARRKGPPPPPPK----------RLSSVSGP----SPEPPPLDESPGPK 814
Query: 224 FRGGGRSGGGLAGP--PLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPP 281
G L+ P P GP PAG SD+EE E P PE G P
Sbjct: 815 EGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEE--------PGPE--------GTP 858
Query: 282 PLTATSPPQQPHALPPHA--HRRPASALPSRRD-----GTPTKTTPCEIPPPFPNLLQHR 334
P +S P A + +RP A P R+ G T + P +
Sbjct: 859 PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRERE 918
Query: 335 P---PLLAF--------PQAKSASRTPGDG--VSRLPVLCHSKEPAGSTPAPQVPARERE 381
P LLAF P A S TPG+ S LP S PA P P P+ +
Sbjct: 919 PLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQ 978
Query: 382 TPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSG---QPRGERELPNSHSMIC------ 432
P PP P P L S +R + PP + G P S+ C
Sbjct: 979 PPVPPCPGPG-----LESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFS 1033
Query: 433 -----PKAAGAPAAPPAP 445
P+ P PP P
Sbjct: 1034 GPKLAPRLGPRPVPPPRP 1051
Score = 51.6 bits (122), Expect = 3e-06
Identities = 68/250 (27%), Positives = 84/250 (33%), Gaps = 32/250 (12%)
Query: 218 EMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGAD--SDSEESEAIYEEMK--------YP 267
E +G RG G S A P GG P+PP + +E + + +
Sbjct: 617 ESIGARSRGSGHSQEQPAPQP-SGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFM 675
Query: 268 LPEEAGEGRANGPPPLT--ATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPP 325
P+ + A GPPP A S P A PP R + R G E
Sbjct: 676 YPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEG 735
Query: 326 PFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPP 385
P + L L P + RT S P PA TP Q A P
Sbjct: 736 PVGSTLGSYATLTRRPGRSALVRT---SPSVTPT------PARGTPRSQSFALRARRKGP 786
Query: 386 PPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAP 445
PPPPP + GPS P P S P+ P ++ P P PPAP
Sbjct: 787 PPPPPKRLSSVSGPS------PEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAP 840
Query: 446 AALLPGPPKD 455
A GP D
Sbjct: 841 A----GPASD 846
Score = 39.3 bits (90), Expect = 0.015
Identities = 110/446 (24%), Positives = 150/446 (33%), Gaps = 93/446 (20%)
Query: 368 GSTPAPQVPARERETPPPPPPPPAA---NLLLLGPSGRARSHS----TPLPPQGSGQPRG 420
GS +P++ A P P P P A + +G R HS P P G P
Sbjct: 587 GSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQ 646
Query: 421 ERELPNSHSM---ICPKAAGAPAAP-------PAPAALLPGPPKDK--AVSYTMVYSAV- 467
ER LP +C G P +P++ PGPP A SY A
Sbjct: 647 ERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATP 706
Query: 468 ------KVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAA 521
K +HS+ GP G E + E + G T +R P G +
Sbjct: 707 PDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRP------------GRS 754
Query: 522 AGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGA 581
A V SP P P G TP A A K PP + V
Sbjct: 755 ALV------RTSPSVTPTPARG--TPRSQSFALRARRKGPPPPPPKRLSSVSGPS---PE 803
Query: 582 PSPMVKIQLQEQGTDGGAFASIS-CAHVIASAGTP-------EEEEEEVGAATFGAGWAL 633
P P+ + ++G G ++S A G P + EEEE G G
Sbjct: 804 PPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGP----EGTPP 859
Query: 634 QRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSGIPVRSQGAEGLLARI 693
R G + L E+G + G RE P G+ ++ + R
Sbjct: 860 SR-----GSSGEGLPFAEEGNLTIKQRPKPAGPPPRET--PVPPGLDFNLTESDTVKRRP 912
Query: 694 HHGDRGGSRTALPIPCQTFPACHRNGDFTGGYRLGRSASTSGVRQVVLHTPRPC-SQPRD 752
+R +TAL G +++T G L +P P S P
Sbjct: 913 KCREREPLQTAL-------------------LAFGVASATPG-PAAPLPSPTPGESPPAS 952
Query: 753 ALSQPHP-ALP---LPLPLPPQPARE 774
+L QP P +LP +P PL P PA +
Sbjct: 953 SLPQPEPSSLPAQGVPTPLAPSPAMQ 978
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 62.4 bits (150), Expect = 2e-09
Identities = 118/438 (26%), Positives = 148/438 (33%), Gaps = 91/438 (20%)
Query: 63 MPASQEHTPHPCRSAMA---PRSLSCHSVGSMDSVGGGPGG----ASGGLTEDSSTRRPP 115
+P E P C S P + + GS S GP A L +T P
Sbjct: 732 LPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDP 791
Query: 116 AKPRRHPSTKLSMVGPGSG-----AETPPSKKAGSQKPTPE--GRES----SRKVPPQKP 164
+P+R S LS GP G AE P GS GR + S V P
Sbjct: 792 PRPKRR-SHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA 850
Query: 165 RRSPNTQ-LSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEEPVYIEMVGDV 223
R +P +Q ++ PP P P+ R S V+G + E P E G
Sbjct: 851 RGTPRSQSFALRARRKGPPPPPPK----------RLSSVSGP----SPEPPPLDESPGPK 896
Query: 224 FRGGGRSGGGLAGP--PLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPP 281
G L+ P P GP PAG SD+EE E P PE G P
Sbjct: 897 EGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEE--------PGPE--------GTP 940
Query: 282 PLTATSPPQQPHALPPHA--HRRPASALPSRRD-----GTPTKTTPCEIPPPFPNLLQHR 334
P +S P A + +RP A P R+ G T + P +
Sbjct: 941 PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRERE 1000
Query: 335 P---PLLAF--------PQAKSASRTPGDG--VSRLPVLCHSKEPAGSTPAPQVPARERE 381
P LLAF P A S TPG+ S LP S PA P P P+ +
Sbjct: 1001 PLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQ 1060
Query: 382 TPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSG---QPRGERELPNSHSMIC------ 432
P PP P P L S +R + PP + G P S+ C
Sbjct: 1061 PPVPPCPGPG-----LESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFS 1115
Query: 433 -----PKAAGAPAAPPAP 445
P+ P PP P
Sbjct: 1116 GPKLAPRLGPRPVPPPRP 1133
Score = 51.6 bits (122), Expect = 3e-06
Identities = 68/250 (27%), Positives = 84/250 (33%), Gaps = 32/250 (12%)
Query: 218 EMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGAD--SDSEESEAIYEEMK--------YP 267
E +G RG G S A P GG P+PP + +E + + +
Sbjct: 699 ESIGARSRGSGHSQEQPAPQP-SGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFM 757
Query: 268 LPEEAGEGRANGPPPLT--ATSPPQQPHALPPHAHRRPASALPSRRDGTPTKTTPCEIPP 325
P+ + A GPPP A S P A PP R + R G E
Sbjct: 758 YPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEG 817
Query: 326 PFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPP 385
P + L L P + RT S P PA TP Q A P
Sbjct: 818 PVGSTLGSYATLTRRPGRSALVRT---SPSVTPT------PARGTPRSQSFALRARRKGP 868
Query: 386 PPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAP 445
PPPPP + GPS P P S P+ P ++ P P PPAP
Sbjct: 869 PPPPPKRLSSVSGPS------PEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAP 922
Query: 446 AALLPGPPKD 455
A GP D
Sbjct: 923 A----GPASD 928
Score = 39.3 bits (90), Expect = 0.015
Identities = 110/446 (24%), Positives = 150/446 (33%), Gaps = 93/446 (20%)
Query: 368 GSTPAPQVPARERETPPPPPPPPAA---NLLLLGPSGRARSHS----TPLPPQGSGQPRG 420
GS +P++ A P P P P A + +G R HS P P G P
Sbjct: 669 GSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQ 728
Query: 421 ERELPNSHSM---ICPKAAGAPAAP-------PAPAALLPGPPKDK--AVSYTMVYSAV- 467
ER LP +C G P +P++ PGPP A SY A
Sbjct: 729 ERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATP 788
Query: 468 ------KVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAA 521
K +HS+ GP G E + E + G T +R P G +
Sbjct: 789 PDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRP------------GRS 836
Query: 522 AGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGA 581
A V SP P P G TP A A K PP + V
Sbjct: 837 ALV------RTSPSVTPTPARG--TPRSQSFALRARRKGPPPPPPKRLSSVSGPS---PE 885
Query: 582 PSPMVKIQLQEQGTDGGAFASIS-CAHVIASAGTP-------EEEEEEVGAATFGAGWAL 633
P P+ + ++G G ++S A G P + EEEE G G
Sbjct: 886 PPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGP----EGTPP 941
Query: 634 QRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSGIPVRSQGAEGLLARI 693
R G + L E+G + G RE P G+ ++ + R
Sbjct: 942 SR-----GSSGEGLPFAEEGNLTIKQRPKPAGPPPRET--PVPPGLDFNLTESDTVKRRP 994
Query: 694 HHGDRGGSRTALPIPCQTFPACHRNGDFTGGYRLGRSASTSGVRQVVLHTPRPC-SQPRD 752
+R +TAL G +++T G L +P P S P
Sbjct: 995 KCREREPLQTAL-------------------LAFGVASATPG-PAAPLPSPTPGESPPAS 1034
Query: 753 ALSQPHP-ALP---LPLPLPPQPARE 774
+L QP P +LP +P PL P PA +
Sbjct: 1035 SLPQPEPSSLPAQGVPTPLAPSPAMQ 1060
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.133 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,344,925
Number of Sequences: 37866
Number of extensions: 3713209
Number of successful extensions: 39206
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 348
Number of HSP's successfully gapped in prelim test: 2025
Number of HSP's that attempted gapping in prelim test: 19253
Number of HSP's gapped (non-prelim): 12986
length of query: 841
length of database: 18,247,518
effective HSP length: 111
effective length of query: 730
effective length of database: 14,044,392
effective search space: 10252406160
effective search space used: 10252406160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.