Guide to the Human Genome
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Name: SHANK1 Sequence: fasta or formatted (2161aa) NCBI GI: 120587025
Description:

SH3 and multiple ankyrin repeat domains 1

Referenced in:

Ankyrin Family
Growth Hormone and Related Hormones
Synapses
Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.4        204           4
 C cysteine            0.6         14           2
 D aspartate           3.8         83           2
 E glutamate           5.4        116           3
 F phenylalanine       2.7         58           2
 G glycine            11.8        255           7
 H histidine           3.0         65           6
 I isoleucine          1.9         40           3
 K lysine              3.3         72           2
 L leucine             8.9        192           3
 M methionine          1.3         28           2
 N asparagine          1.4         31           3
 P proline            14.3        310           5
 Q glutamine           3.5         75           2
 R arginine            6.1        132           3
 S serine             10.9        235           4
 T threonine           4.9        105           2
 V valine              4.2         91           2
 W tryptophan          0.7         16           1
 Y tyrosine            1.8         39           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SH3 and multiple ankyrin repeat domains 1 
SHANK2                0.279   SH3 and multiple ankyrin repeat domains 2 isoform 1...
SHANK3                0.198   SH3 and multiple ankyrin repeat domains 3 
LOC100133890          0.101   PREDICTED: similar to Shank2E 
SHANK2                0.047   SH3 and multiple ankyrin repeat domains 2 isoform 2 ...
NACA                  0.028   nascent polypeptide-associated complex alpha subuni...
FLJ22184              0.027   PREDICTED: hypothetical protein FLJ22184 
PRR12                 0.027   proline rich 12 
FLJ22184              0.024   PREDICTED: hypothetical protein FLJ22184 
FLJ22184              0.023   PREDICTED: hypothetical protein LOC80164 
COL3A1                0.023   collagen type III alpha 1 preproprotein 
COL1A1                0.022   alpha 1 type I collagen preproprotein 
KDM6B                 0.022   lysine (K)-specific demethylase 6B 
WIPF1                 0.021   WAS/WASL interacting protein family, member 1 [Homo...
WIPF1                 0.021   WAS/WASL interacting protein family, member 1 
COL2A1                0.019   collagen, type II, alpha 1 isoform 1 precursor [Hom...
COL2A1                0.019   collagen, type II, alpha 1 isoform 2 precursor [Hom...
FMN2                  0.019   formin 2 
ANKK1                 0.017   ankyrin repeat and kinase domain containing 1 
KIAA1522              0.016   hypothetical protein LOC57648 
RAPH1                 0.016   Ras association and pleckstrin homology domains 1 is...
PRB3                  0.016   proline-rich protein BstNI subfamily 3 precursor [H...
PRB2                  0.016   proline-rich protein BstNI subfamily 2 
TAF4                  0.016   TBP-associated factor 4 
ANKRD28               0.016   ankyrin repeat domain 28 
COL5A1                0.016   alpha 1 type V collagen preproprotein 
ANK2                  0.016   ankyrin 2 isoform 3 
ANK2                  0.016   ankyrin 2 isoform 2 
ANK2                  0.016   ankyrin 2 isoform 1 
ANK3                  0.016   ankyrin 3 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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