Guide to the Human Genome
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Search of human proteins with 32964830

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
         (703 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]              1527   0.0  
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]       745   0.0  
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]       745   0.0  
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          711   0.0  
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    474   e-134
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   470   e-132
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   469   e-132
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   461   e-129
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     452   e-127
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      448   e-126
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     447   e-125
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   447   e-125
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   441   e-124
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   441   e-124
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   441   e-123
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   441   e-123
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   441   e-123
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     437   e-122
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               435   e-122
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      432   e-121
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        431   e-120
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   431   e-120
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   431   e-120
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   431   e-120
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              431   e-120
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  426   e-119
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         424   e-118
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   423   e-118
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   423   e-118
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   423   e-118

>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 1527 bits (3953), Expect = 0.0
 Identities = 703/703 (100%), Positives = 703/703 (100%)

Query: 1   MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK 60
           MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK
Sbjct: 1   MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK 60

Query: 61  GQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFS 120
           GQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFS
Sbjct: 61  GQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFS 120

Query: 121 RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGV 180
           RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGV
Sbjct: 121 RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGV 180

Query: 181 PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG 240
           PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG
Sbjct: 181 PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG 240

Query: 241 LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE 300
           LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE
Sbjct: 241 LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE 300

Query: 301 PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP 360
           PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP
Sbjct: 301 PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP 360

Query: 361 GLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP 420
           GLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP
Sbjct: 361 GLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP 420

Query: 421 GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 480
           GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP
Sbjct: 421 GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 480

Query: 481 GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG 540
           GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG
Sbjct: 481 GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG 540

Query: 541 IAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYN 600
           IAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYN
Sbjct: 541 IAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYN 600

Query: 601 GHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQAS 660
           GHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQAS
Sbjct: 601 GHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQAS 660

Query: 661 GGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT 703
           GGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT
Sbjct: 661 GGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT 703


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  745 bits (1924), Expect = 0.0
 Identities = 384/678 (56%), Positives = 441/678 (65%), Gaps = 39/678 (5%)

Query: 42  KYIQPMQKGP-VGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKP 100
           +Y++ +Q  P +G      KG+  E+PL      L+GE GP G+PGPRGPPGPPG PG  
Sbjct: 88  QYMKEIQPAPRMGKEAVPKKGK--EIPLA----SLRGEQGPRGEPGPRGPPGPPGLPGH- 140

Query: 101 GMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160
             G PG+ G+PGP G PG   +GK G PG+PGK G  G PG +GE G +G+ G  G PGP
Sbjct: 141 --GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP 195

Query: 161 PGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPG 220
            G PGP G+   GKPG  G+PG PG +G+ GP+G PGP G RG KGD G G PG PG  G
Sbjct: 196 QGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKG 255

Query: 221 QGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV 280
             G  GPPG  G  G+GKPG+ G PG  G  G+ G PG PGP+G  G  G +GPPG+ G+
Sbjct: 256 PPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI 315

Query: 281 GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRG 340
           G PG  G+PG  G  G KGE G  G PG  G  G G PG PGPKGDRG  GVPG LG RG
Sbjct: 316 GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRG 375

Query: 341 EPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG 400
           E G  G PG  GP G  G PG+PG  G PG  G PGPKGE G  GP G PG +G+ G  G
Sbjct: 376 EKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQG 435

Query: 401 LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
             GKPG  GE G PG  G PGP GPKGE G  G PG PGV G LG KG+ G+PG  GL+G
Sbjct: 436 FPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQG 495

Query: 461 PSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGS------ 514
           P GIPG+ GP+GPIGP G+PG KGEPGLPGPPG    G+PG AG  GPPG PG+      
Sbjct: 496 PPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQ 555

Query: 515 PGITGPPGPPGPPGPPG----APGAFDE------TGIAGLHLPNGGVEGAVLGKGGKPQF 564
           PG+ GPPGPPGPPGPP      P    E       GI G+  P+    GA  GK G P  
Sbjct: 556 PGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPH--AYGAKKGKNGGP-- 611

Query: 565 GLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAY 624
                 A+  PAFTA LT+PFP  G PVKF++ LYNG   YNP TGIFTC V GVYYFAY
Sbjct: 612 ------AYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAY 665

Query: 625 HVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANG 684
           HVH KG NVWVAL+KNN P  YTYDEYKKG+LDQASG AVL LRP D+V++QMPS+QA G
Sbjct: 666 HVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAG 725

Query: 685 LYSTEYIHSSFSGFLLCP 702
           LY+ +Y+HSSFSG+LL P
Sbjct: 726 LYAGQYVHSSFSGYLLYP 743



 Score =  188 bits (478), Expect = 1e-47
 Identities = 126/278 (45%), Positives = 143/278 (51%), Gaps = 43/278 (15%)

Query: 23  GPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGE---P 79
           GPR   G       G  P +   P   GP+GPP   G       P P      KGE    
Sbjct: 372 GPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIG------FPGP------KGEGGIV 419

Query: 80  GPPGKPGPRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVG 135
           GP G PGP+G PG  GFPGKPG    +G PG+ G PGP GP      G+AG  G+PG  G
Sbjct: 420 GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGP-----KGEAGQKGVPGLPG 474

Query: 136 PPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQ--GE 189
            PG  G +GEPGI GDQGL+GPPG PG+ GPSG      IPG  G  G+PGPPGF   G+
Sbjct: 475 VPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK 534

Query: 190 PGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGL----PGPAGLGKP----GL 241
           PG  G  GPPG  G  G    GQPGLPG PG  G PGPP +    P P G   P    G+
Sbjct: 535 PGVAGLHGPPGKPGALGPQ--GQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGI 592

Query: 242 DGL--PGAPG-DKGESGPPGVPGPRGEPGAVGPKGPPG 276
           DG+  P A G  KG++G P    P        P  P G
Sbjct: 593 DGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVG 630



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 44/129 (34%), Positives = 54/129 (41%), Gaps = 12/129 (9%)

Query: 457 GLRGPSGIPGLQ-GPAGPIGPQGLPGLKGEP--GLPGPPGEGRAGEPGTAGPTGPPGVPG 513
           GL     +P LQ G   P  PQ +  ++  P  G    P +G+  E   A   G  G  G
Sbjct: 67  GLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK--EIPLASLRGEQGPRG 124

Query: 514 SPGITGPPGPPGPPGP--PGAPGAFDETGIAGLHLPN----GGVEGAVLGKGGKPQFG-L 566
            PG  GPPGPPG PG   PG  G     G  G+  P      G  GA+   G K + G  
Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184

Query: 567 GELSAHATP 575
           GE+     P
Sbjct: 185 GEIGPMGIP 193


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  745 bits (1924), Expect = 0.0
 Identities = 384/678 (56%), Positives = 441/678 (65%), Gaps = 39/678 (5%)

Query: 42  KYIQPMQKGP-VGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKP 100
           +Y++ +Q  P +G      KG+  E+PL      L+GE GP G+PGPRGPPGPPG PG  
Sbjct: 88  QYMKEIQPAPRMGKEAVPKKGK--EIPLA----SLRGEQGPRGEPGPRGPPGPPGLPGH- 140

Query: 101 GMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160
             G PG+ G+PGP G PG   +GK G PG+PGK G  G PG +GE G +G+ G  G PGP
Sbjct: 141 --GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP 195

Query: 161 PGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPG 220
            G PGP G+   GKPG  G+PG PG +G+ GP+G PGP G RG KGD G G PG PG  G
Sbjct: 196 QGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKG 255

Query: 221 QGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV 280
             G  GPPG  G  G+GKPG+ G PG  G  G+ G PG PGP+G  G  G +GPPG+ G+
Sbjct: 256 PPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI 315

Query: 281 GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRG 340
           G PG  G+PG  G  G KGE G  G PG  G  G G PG PGPKGDRG  GVPG LG RG
Sbjct: 316 GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRG 375

Query: 341 EPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG 400
           E G  G PG  GP G  G PG+PG  G PG  G PGPKGE G  GP G PG +G+ G  G
Sbjct: 376 EKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQG 435

Query: 401 LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
             GKPG  GE G PG  G PGP GPKGE G  G PG PGV G LG KG+ G+PG  GL+G
Sbjct: 436 FPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQG 495

Query: 461 PSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGS------ 514
           P GIPG+ GP+GPIGP G+PG KGEPGLPGPPG    G+PG AG  GPPG PG+      
Sbjct: 496 PPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQ 555

Query: 515 PGITGPPGPPGPPGPPG----APGAFDE------TGIAGLHLPNGGVEGAVLGKGGKPQF 564
           PG+ GPPGPPGPPGPP      P    E       GI G+  P+    GA  GK G P  
Sbjct: 556 PGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPH--AYGAKKGKNGGP-- 611

Query: 565 GLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAY 624
                 A+  PAFTA LT+PFP  G PVKF++ LYNG   YNP TGIFTC V GVYYFAY
Sbjct: 612 ------AYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAY 665

Query: 625 HVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANG 684
           HVH KG NVWVAL+KNN P  YTYDEYKKG+LDQASG AVL LRP D+V++QMPS+QA G
Sbjct: 666 HVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAG 725

Query: 685 LYSTEYIHSSFSGFLLCP 702
           LY+ +Y+HSSFSG+LL P
Sbjct: 726 LYAGQYVHSSFSGYLLYP 743



 Score =  188 bits (478), Expect = 1e-47
 Identities = 126/278 (45%), Positives = 143/278 (51%), Gaps = 43/278 (15%)

Query: 23  GPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGE---P 79
           GPR   G       G  P +   P   GP+GPP   G       P P      KGE    
Sbjct: 372 GPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIG------FPGP------KGEGGIV 419

Query: 80  GPPGKPGPRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVG 135
           GP G PGP+G PG  GFPGKPG    +G PG+ G PGP GP      G+AG  G+PG  G
Sbjct: 420 GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGP-----KGEAGQKGVPGLPG 474

Query: 136 PPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQ--GE 189
            PG  G +GEPGI GDQGL+GPPG PG+ GPSG      IPG  G  G+PGPPGF   G+
Sbjct: 475 VPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK 534

Query: 190 PGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGL----PGPAGLGKP----GL 241
           PG  G  GPPG  G  G    GQPGLPG PG  G PGPP +    P P G   P    G+
Sbjct: 535 PGVAGLHGPPGKPGALGPQ--GQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGI 592

Query: 242 DGL--PGAPG-DKGESGPPGVPGPRGEPGAVGPKGPPG 276
           DG+  P A G  KG++G P    P        P  P G
Sbjct: 593 DGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVG 630



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 44/129 (34%), Positives = 54/129 (41%), Gaps = 12/129 (9%)

Query: 457 GLRGPSGIPGLQ-GPAGPIGPQGLPGLKGEP--GLPGPPGEGRAGEPGTAGPTGPPGVPG 513
           GL     +P LQ G   P  PQ +  ++  P  G    P +G+  E   A   G  G  G
Sbjct: 67  GLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK--EIPLASLRGEQGPRG 124

Query: 514 SPGITGPPGPPGPPGP--PGAPGAFDETGIAGLHLPN----GGVEGAVLGKGGKPQFG-L 566
            PG  GPPGPPG PG   PG  G     G  G+  P      G  GA+   G K + G  
Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184

Query: 567 GELSAHATP 575
           GE+     P
Sbjct: 185 GEIGPMGIP 193


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  711 bits (1834), Expect = 0.0
 Identities = 347/629 (55%), Positives = 406/629 (64%), Gaps = 10/629 (1%)

Query: 76  KGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVG 135
           +G PGPPG  GPRG PGP G PGKPG G PGL G+PG  GPPG S +GK G PGLPGK G
Sbjct: 59  QGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPG 118

Query: 136 PPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGE 195
             G  G +G+ G  G  G RGPPGPPG+PGP+GI++PGKPG QG  G PG +G PG +G 
Sbjct: 119 ERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA 178

Query: 196 PGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESG 255
           PG PG  G KG+ G G PG PG  G  G  GP G  GP G+GK G +G+PG PG KG+ G
Sbjct: 179 PGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRG 238

Query: 256 PPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY 315
            PG  GP G PG  GP G  G +G+G PGAAG PG  G  G KG PG  G  G  GP G+
Sbjct: 239 FPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF 298

Query: 316 GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPP 375
           G PGLPG KG+RGPAG+PG  G +GE G  G PG+ G  G  G  G  G  G+PG  G P
Sbjct: 299 GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLP 358

Query: 376 GPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRP 435
           GPKGE GP GP G PG +G++G  G  GKPG PG+ GL G  G PG  GPKG+PG  G P
Sbjct: 359 GPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPP 418

Query: 436 GGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEG 495
           G PG  G  G KG  G  G+ G RG  GIPG +GP GP G  G PG KG+PG PGPPG  
Sbjct: 419 GLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPA 478

Query: 496 RAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVE-GA 554
                G  GPTGPPG PG  G +G PG PGPPGPPG PG           +P G ++ G 
Sbjct: 479 GIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQ--------AVMPEGFIKAGQ 530

Query: 555 VLGKGGKPQFGLGE-LSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFT 613
                G P     + ++     AFT +L+  +PA G P+ FD+ LYN    Y+P TGIFT
Sbjct: 531 RPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFT 590

Query: 614 CPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQV 673
           C + G+YYF+YHVHVKGT+VWV LYKN  P  YTYDEY KGYLDQASG A++ L  NDQV
Sbjct: 591 CQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQV 650

Query: 674 WVQMPSDQANGLYSTEYIHSSFSGFLLCP 702
           W+Q+P+ ++NGLYS+EY+HSSFSGFL+ P
Sbjct: 651 WLQLPNAESNGLYSSEYVHSSFSGFLVAP 679



 Score =  276 bits (707), Expect = 4e-74
 Identities = 178/417 (42%), Positives = 205/417 (49%), Gaps = 81/417 (19%)

Query: 251 KGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLI 310
           +GE G PG PGP G  G  GP GPPG  G G PG             +GEPG  GPPG  
Sbjct: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGL------------QGEPGLPGPPGPS 103

Query: 311 GPTGYGMPGLP---------GPKGDRGPAGVPGLLGDRGEPG--------EDGEPGEQGP 353
                G+PGLP         GPKGD GPAG+PG  G  G PG          G+PG+QGP
Sbjct: 104 AVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGP 163

Query: 354 QGLGGPPGLP--------------------GSAGLPGRRGPPGPKGEAGPGGPPGVPGIR 393
            G  GP G P                    G+ G PG RG PGP+G  GP GPPGV    
Sbjct: 164 TGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGV---- 219

Query: 394 GDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRP--GGPGVAGALGQ---KG 448
           G +G +G+ G+PG+ G+RG PG  GP GP GP+G PG  G    G PG AGA GQ    G
Sbjct: 220 GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPG 279

Query: 449 DLGLPGQPGLRGP--------SGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAGE 499
             GLPG PG+ GP         G+PGL+G  GP G  G PG KGE G  G PG+ G  G 
Sbjct: 280 TKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGP 339

Query: 500 PGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGA 554
           PG  GP GP G+PGS G+ GP G  GP GP G PGA  E G  G     G     G++G 
Sbjct: 340 PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGP 399

Query: 555 VLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGI 611
             G  G P    G+      P     +  P  A GMP       +NG +G   A GI
Sbjct: 400 -KGNPGLPG-PKGDPGVGGPPGLPGPV-GPAGAKGMPG------HNGEAGPRGAPGI 447



 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 68/172 (39%), Positives = 76/172 (44%), Gaps = 26/172 (15%)

Query: 415 GAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPI 474
           G  GP   T  +    +T +  G  V G  G  G  G  G  G  GPSG PG  G     
Sbjct: 30  GIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG----- 84

Query: 475 GPQGLPGLKGEPGLPGPPG---------EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPG 525
              G PGL+GEPGLPGPPG          G  G+PG  GP GP G  G  G+ GP GPPG
Sbjct: 85  --YGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPG 142

Query: 526 PPGPPG-----APGAFDETGIAGLHLPNG-----GVEGAVLGKGGKPQFGLG 567
           PPG PG      PG   + G  G   P G     G  G     G K + G G
Sbjct: 143 PPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYG 194


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  474 bits (1221), Expect = e-134
 Identities = 289/657 (43%), Positives = 334/657 (50%), Gaps = 100/657 (15%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP+   G  G  G  G + +  +   Q  P  P F   KG+          M + G PG 
Sbjct: 840  GPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGE----------MGVMGTPGQ 889

Query: 82   PGKPGPRGPPGPPG------FPGKPG-MGKPGLHGQPGPAGPPG---------------- 118
            PG PGP G PG PG      FPG  G  G PGL G  G  G PG                
Sbjct: 890  PGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQ 949

Query: 119  ------------FSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGP 166
                            G  G PG PG  G  GQ G  G+PG +GD G+ G PG PGLPGP
Sbjct: 950  KGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGP 1009

Query: 167  SG----ITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQG 222
             G    + +PG PG +GVPG PG QG PG  G+ G  G++G  G  G+G PGL G  G  
Sbjct: 1010 KGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQ 1069

Query: 223  GAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV- 280
            G  G PG PG  G  G  G+ G+PG+PG KG  G  G PG  G PG  G KG PG+DG+ 
Sbjct: 1070 GIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIP 1129

Query: 281  GVPGAAGLPG---PQGPSGAKGEPGTRGPPGLIGPTGY------GMPGLPGPKGDRGP-- 329
            GV G AGLPG   P GP+G KGEPG+ G PG  G  G       G PG PG KGD+G   
Sbjct: 1130 GVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKG 1189

Query: 330  -AGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPG 388
              G PGL G  G PG  GE G  GP G  G PGLPGS G        GPKG+ GP G PG
Sbjct: 1190 EVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPG----HATEGPKGDRGPQGQPG 1245

Query: 389  VPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKG 448
            +PG+ G  GP GL G  GV G++G PG  G PG  GPKG+PGF G PG  G  G  G KG
Sbjct: 1246 LPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKG 1305

Query: 449  DLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG--EGRAGEPGTAGPT 506
            D+G PG PG +GP G+PGLQG  G  G QG+PG KG PG PGPPG  +   GEPG  GP 
Sbjct: 1306 DMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPE 1365

Query: 507  GPPGVPGSPGITGP------------PGPPGPPGPPGAPGAFDETGIAGLHLPNG----- 549
            GPPG+ G  G+ GP            PGPPG PG  GAPG   E G AG   P G     
Sbjct: 1366 GPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPP 1425

Query: 550  ---GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHS 603
               G+ G+ +G  G P    G L        +  +  P   SG  +     LY+G+S
Sbjct: 1426 GPDGLPGS-MGPPGTPSVDHGFL----VTRHSQTIDDPQCPSGTKI-----LYHGYS 1472



 Score =  437 bits (1124), Expect = e-122
 Identities = 295/694 (42%), Positives = 334/694 (48%), Gaps = 142/694 (20%)

Query: 8   LSSLLLLL---LVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYL 64
           LS  LLLL   L+L       A+ GG AG   G      ++  QKG  G P  +G   + 
Sbjct: 5   LSVWLLLLPAALLLHEEHSRAAAKGGCAGSGCGKCDCHGVKG-QKGERGLPGLQGVIGFP 63

Query: 65  EMPLPLLPMDLKG------EPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPG 118
            M  P  P    G      EPG PG  G RGPPG  G+PG PG+  PG+ GQ GP GPPG
Sbjct: 64  GMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGL--PGIPGQDGPPGPPG 121

Query: 119 F-------SRMGKAGPPGLP---GKVGPPGQPGLRGEPG-IRGD------QGLRGPPGPP 161
                      G  GPPGLP   G  GPPG PG++G+PG I G       +G RG PG P
Sbjct: 122 IPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIP 181

Query: 162 GLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGL-----------KGDNGV 210
           G PGP     PG PG QG  GPPGF G PGP G PGPPG++G            KGD GV
Sbjct: 182 GTPGP-----PGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGV 236

Query: 211 -GQPGLPG-----------APGQGGAPGPPGLPGPAGL------GKPGLDGLPGAPGDKG 252
            G PG+PG             G+ G  G PG  G  G+      GKPG  G PG  GDKG
Sbjct: 237 SGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKG 296

Query: 253 ESGPPGVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGL---PGPQGPSGAKGEPGTRGPPG 308
           E G PG PG  G PG +G +GP G  G  G PG  G+    GP G  G +G PGT GP G
Sbjct: 297 EKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRG 356

Query: 309 LIGPTGY-GMPGLPGPKG--DRGPAGVPGLLGDRGEPGEDGEPGEQ--GPQGLGGPPGLP 363
             GP G+ G+PG PGP G    G AG PG  G+RGE G+ G PG    GP G  G PG P
Sbjct: 357 EPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPP 416

Query: 364 GSAGLPGRRG--------PPGPKGEAGPGGPPGVPGI----------------------R 393
           GS G PG+ G         PGP G+ GP G PG PG                       R
Sbjct: 417 GSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYR 476

Query: 394 GDQGPS------GLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGAL--- 444
           G  GP       G  G+PG  G+RGLPG  G  G  GP+G PG  G+PG  G  G     
Sbjct: 477 GPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFD 536

Query: 445 ----GQKGDLGLPGQPGLRGPSGIP------------------GLQGPAGPIGPQGLPGL 482
               G KGD G PGQPG+ G +G P                  GL+G  GP G  G PG 
Sbjct: 537 LRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGS 596

Query: 483 KGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGP----PGPPGAPGAFDE 538
           +G+ G PGPPG G AG  G  G  G PG PGSPG+ GP G PG     PGPPGA G    
Sbjct: 597 RGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGS 656

Query: 539 TGIAGLHLPNG-----GVEGAVLGKGGKPQFGLG 567
            G  G     G     G  G    KG   Q G+G
Sbjct: 657 PGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIG 690



 Score =  430 bits (1105), Expect = e-120
 Identities = 278/654 (42%), Positives = 329/654 (50%), Gaps = 144/654 (22%)

Query: 45   QPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGP-------RGPPGPPGFP 97
            QP  KG  G P R+G      +P P     L G+PG  G+PG        +G  G PGFP
Sbjct: 493  QPGAKGDRGLPGRDGVAG---VPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFP 549

Query: 98   GKPGM-------GKPGLHGQPGPAGPPGFSRM-GKAGPPG---LPGK---VGPPGQPGL- 142
            G+PGM       G+ G  G PGP G PG   + G+ GPPG    PG     GPPG PG  
Sbjct: 550  GQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYG 609

Query: 143  -RGEPGIRGDQGLRGPPGPPGLPGPSG-----ITIPGKPGAQGVPGPPGFQGEPGPQGEP 196
              G  G +G  G  G PG PGLPGP G     + +PG PGA+G+PG PGF G  G +G P
Sbjct: 610  PAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFP 669

Query: 197  GPPGDRGLKGDNG-VGQPGL-----------------------PGAPGQGGAPGPPGLPG 232
            G PG  GL G+ G VGQPG+                       PG PG  G PG PG+ G
Sbjct: 670  GTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQG 729

Query: 233  PAG---------LGKPGLDGLPGAPGDKGESGPPGVPG------PRGEPGAVGPKGPPGV 277
              G          G PGL G+PG PG+KG  G PGVPG      P G  G  G  GPPG+
Sbjct: 730  QKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGL 789

Query: 278  DG-VGVPGAAGL--PGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGL--PGPKGDRGP-- 329
             G VG PG  G+  PG +GP G +G PG  GPPG+ G  G+ G PGL  PGPKGD+G   
Sbjct: 790  PGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQG 849

Query: 330  -------AGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG 382
                   +G+PGL G +G PG  G PG +G  G+ G PG PGS G  G  G PG KG+ G
Sbjct: 850  LPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHG 909

Query: 383  -PG--GPPGVPGIRGDQGPSGLAGKPGV-------------------------------- 407
             PG  GP G PG++GD+G  GL GKPG                                 
Sbjct: 910  FPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRG 969

Query: 408  -PGERGLPGAHGP---PGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSG 463
             PG  G+PG  G    PG  GPKG+PG +G PG PG+ G  G  G +GLPG PG +G  G
Sbjct: 970  DPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPG 1029

Query: 464  IPGLQGPAGPIGPQGLPGLKGE--------PGLPGPPGE-------GRAGEPGTAGPTGP 508
            IPG QG  G  G +G  G KG+        PGL G  G+       G  GE G  G  G 
Sbjct: 1030 IPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGI 1089

Query: 509  PGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKP 562
            PG+PGSPG+ G PG  G PG PG PG   + G+ GL     G+ G V G+ G P
Sbjct: 1090 PGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGL----DGIPG-VKGEAGLP 1138



 Score =  405 bits (1041), Expect = e-113
 Identities = 278/682 (40%), Positives = 314/682 (46%), Gaps = 160/682 (23%)

Query: 23  GPRASSG--GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPG 80
           GP    G  G  G   G+ P   ++  ++G  G P   G         P LP  L+G  G
Sbjct: 148 GPPGLPGMKGDPGEILGHVPGMLLKG-ERGFPGIPGTPGP--------PGLP-GLQGPVG 197

Query: 81  PPGKPGPRGPPGPPGFPGKPGM------------------GKPGLHGQP----------- 111
           PPG  GP GPPGPPG PG+ G                   G PG+ GQ            
Sbjct: 198 PPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATK 257

Query: 112 ---GPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGL----- 163
              G  G PGF  M   G  G PGK GP G+PG  G+ G +G  G  G PG PGL     
Sbjct: 258 GEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQG 317

Query: 164 ----------PGPSGITI-------------PGKPGAQGVPGP---PGFQGEPGP----- 192
                     PGP GI I             PG PG +G PGP   PG  G+PGP     
Sbjct: 318 PQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPV 377

Query: 193 ---QGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG-----LDGL 244
               G PG PG+RG KGD G     LPG  G+ G PGPPG PGP   G+PG     ++  
Sbjct: 378 PGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPP--GQPGYTNGIVECQ 435

Query: 245 PGAPGDKGESGPPGVPGPRGE-------------------PGAVGPKGPPGVDGV-GVPG 284
           PG PGD+G  G PG PG  GE                    G  GP+GPPG  G  G PG
Sbjct: 436 PGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPG 495

Query: 285 AAGLPGPQGPSGAKGEPGTRGPPGLIG-PTGYGMPG-------LPGPKGDRGPAGVPGLL 336
           A G  G  G  G  G PG +G PGLIG P   G PG       L G KGD G  G PG+ 
Sbjct: 496 AKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMT 555

Query: 337 GDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGV------- 389
           G  G PG DG PG  GP+G  G  GL G  G PG  G PG +G+ GP GPPG        
Sbjct: 556 GRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIG 615

Query: 390 ----------PGIRGDQGPSGLAGK----PGVPGERGLPGAHGPPGPTGPKGEPGFTGRP 435
                     PG  G  GP G  GK    PG PG  GLPG+ G PGP G +G PG  GRP
Sbjct: 616 DKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRP 675

Query: 436 GGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE- 494
           G PG  GA+GQ G +G PG PG +G  G+PG  GP G  G  G  GL G PG+ G  GE 
Sbjct: 676 GLPGEKGAVGQPG-IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEP 734

Query: 495 -----------GRAGEPGTAGPTGPPGVPGSPGITGPPGPP------GPPGPPGAPGAFD 537
                      G  G PGT G  G  GVPG PG  G  GPP      G PGPPG PG+  
Sbjct: 735 GVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVG 794

Query: 538 ETGIAGLHLPNGGVEGAVLGKG 559
             G+ G+  P  G  G   G+G
Sbjct: 795 SPGVPGIGPP--GARGPPGGQG 814



 Score =  382 bits (981), Expect = e-106
 Identities = 256/625 (40%), Positives = 292/625 (46%), Gaps = 132/625 (21%)

Query: 86  GPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVG---PPGQPG 141
           G +G  G  G PG  G+ G PG+ G  GP GPPG  + G  G PGLPG  G   PPG  G
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPG--QKGDTGEPGLPGTKGTRGPPGASG 100

Query: 142 LRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGD 201
             G PG+ G  G  GPPGPPG+PG +G    G+ G  G PG PGF G PGP G PG  GD
Sbjct: 101 YPGNPGLPGIPGQDGPPGPPGIPGCNGTK--GERGPLGPPGLPGFAGNPGPPGLPGMKGD 158

Query: 202 RG----------LKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGL-GKPGLDGLPGAPGD 250
            G          LKG+ G   PG+PG PG  G PG  G  GP G  G PG  G PG PG+
Sbjct: 159 PGEILGHVPGMLLKGERGF--PGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGE 216

Query: 251 KGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLI 310
           KG+ G     GP+G+ G  G  GPPGV G       G    +G  G KGEPG +G PG +
Sbjct: 217 KGQMGL-SFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG-V 274

Query: 311 GPTGYGMPGLPGPK------GDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLP- 363
           G    G PG PGP+      GD+G  G PG  G+ G PG  G  G QG +G  GPPG P 
Sbjct: 275 GEK--GEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPG 332

Query: 364 -----GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGL-----AGKPGVPGERG- 412
                G  G  G RG PG  G  G  GP G PG+ G  GP GL     AG PG PGERG 
Sbjct: 333 IVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGE 392

Query: 413 ----------LPGAH------GPPGPTGPKGEPGFT-----------------GRPGGPG 439
                     LPG        GPPG  GP G+PG+T                 G PG PG
Sbjct: 393 KGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPG 452

Query: 440 VAGALGQK-------------------------GDLGLPGQPGLRGPSGIPGLQGPAGPI 474
             G +G+K                         G++G PGQPG +G  G+PG  G AG  
Sbjct: 453 FIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVP 512

Query: 475 GPQGLPGL----------------------KGEPGLPGPPG-EGRAGEPGTAGPTGPPGV 511
           GPQG PGL                      KG+PG PG PG  GRAG PG  G  G PG 
Sbjct: 513 GPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGP 572

Query: 512 PGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELS- 570
            GSPG  G  G  GPPG  G PG+  +TG  G   P G      +G  G+  F  G  S 
Sbjct: 573 KGSPGSVGLKGERGPPGGVGFPGSRGDTGPPG---PPGYGPAGPIGDKGQAGFPGGPGSP 629

Query: 571 ----AHATPAFTAVLTSPFPASGMP 591
                   P     L  P  A G+P
Sbjct: 630 GLPGPKGEPGKIVPLPGPPGAEGLP 654



 Score =  199 bits (506), Expect = 7e-51
 Identities = 133/322 (41%), Positives = 144/322 (44%), Gaps = 62/322 (19%)

Query: 313 TGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRR 372
           +G G     G KG +G  G+PGL G  G PG  G  G QGP G  G  G PG  G  G R
Sbjct: 34  SGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTR 93

Query: 373 GPP------------------------------GPKGEAGPGGPPGVPGIRGDQGPSGLA 402
           GPP                              G KGE GP GPPG+PG  G+ GP GL 
Sbjct: 94  GPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLP 153

Query: 403 GKPGVP-------------GERGLPGAHGPPGP------TGPKGEPGFTGRPGGPGVAGA 443
           G  G P             GERG PG  G PGP       GP G PGFTG PG PG  G 
Sbjct: 154 GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP 213

Query: 444 LGQKGDLGL-----PGQPGLRGPSGIPGLQGPA-----GPIGPQGLPGLKGEPGLPGPPG 493
            G+KG +GL      G  G +G SG PG+ G A     G    +G  G KGEPG  G PG
Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG 273

Query: 494 EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEG 553
            G  GEPG  GP G PG  G  G  G PG PG PG PG  G     G  G   P  G  G
Sbjct: 274 VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP-PGPPG 332

Query: 554 AVLGKGGKPQFGLGELSAHATP 575
            V+G G  P    GE     TP
Sbjct: 333 IVIGTG--PLGEKGERGYPGTP 352


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  470 bits (1209), Expect = e-132
 Identities = 281/581 (48%), Positives = 316/581 (54%), Gaps = 88/581 (15%)

Query: 49   KGPVGPP-FREGKGQY-LEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM---- 102
            +GP GPP F   KG+    +P P  P  L G  G  G  G RG PGPPG PG+ G+    
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 103  ---GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGL----- 154
               G  G +GQPGP GPPG   +G  GPPG PG  GP GQPGL G PG +GD G      
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 155  ------RGPPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGPQGEPGP------ 198
                  RG PG PG PGP G      +PGK GA G PG  G  G  GP G PGP      
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 199  PGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAG------------LGKPGLDGLP 245
             G  GLKGD+G+ GQPGLPG  G+ G+ G PGLPGP G             G+PGL G+P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 246  GAPGDKG---------------ESGPPGVPGPRGEPGAVGPKG---PPGVDG----VGVP 283
            G  G KG               + G PG PGP+G PG  G  G   PPG+ G    +G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 284  GAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG------YGMPGLPGPKGDRGPAGVPGLLG 337
            G  G+ GP GPSG  G+PG+ G PG  G  G       G+PGLPGPKG+ G  G PG  G
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 338  DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
             +G  G+ G PG  G  G  G PGLPG    PG  GPPGPKG +GP G PG+PG  G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPG---FPGTPGPPGPKGISGPPGNPGLPGEPGPVG 1152

Query: 398  PSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTG--RPGGPGVAGALGQKGDLGL--- 452
              G  G+PG PGE+G PG  G PGP G KGEPG  G   PG PG+ G  GQKGD GL   
Sbjct: 1153 GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGI 1212

Query: 453  PGQPGLRGPS------GIPGLQGPAGPIGPQG--LPGLKGEPGLPGPPGE-GRAGEPGTA 503
            PG PGL GP       G PG+QGP GP G  G  L G KG PG  GPPG  G  G  G  
Sbjct: 1213 PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLP 1272

Query: 504  GPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGL 544
            GP GPPG+PG+ GI G  G PG PG PG PG   + G  GL
Sbjct: 1273 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1313



 Score =  462 bits (1190), Expect = e-130
 Identities = 284/619 (45%), Positives = 322/619 (52%), Gaps = 104/619 (16%)

Query: 46   PMQKGPVGPPFREGKGQY--LEMPLPLLPMDLKGEPGPPGKPGP------RGPPGPPGFP 97
            P Q G  G P  +G+     + +P P  P    G PGPPG PG        GPPGPPGFP
Sbjct: 686  PGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745

Query: 98   GKPGMGKPGLHGQPGPAGPPGFS-RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRG 156
            G  G     L G PGP G PGF   +G  G  G PG  GPPG+ GL G PG +GD G  G
Sbjct: 746  GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 157  PPGPPGLPGPSGITIPGKPGAQGVPGP---------PGFQGEPGPQG--EPGPPGDRGLK 205
             PGP G PG  GI + G PG  G+PGP         PG +G+PGP G   PGPPG+RG  
Sbjct: 806  QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 206  GDNG----VGQPGLPGAPGQGGAPGPPGL---------PGPAG-LGKPGLDGLPGAPGDK 251
            G  G    +G PG PG PG+ GA G PG          PGP G LG PG  G+PG  GD 
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925

Query: 252  GESGPPGVPGPRGEPGAVGPKGPPGVDGV------------GVPGAAGLPGPQGPSGAKG 299
            G  G PG+PGP GE G+ G  G PG  G             G PG  G+PG  GP G +G
Sbjct: 926  GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQG 985

Query: 300  EPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGP 359
             PG  G PGL G  G  +PG PGPKG+ G  G PGL+G  G  G  G+ G  GPQG+ GP
Sbjct: 986  LPGDPGQPGLSGQPG--LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043

Query: 360  PG------LPGSAGLPGRRGP--------------PGPKGEAGPGGPPGVPGIRGDQGPS 399
            PG       PGS GLPG++G               PGPKGE G  G PG PGI+G  G  
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 400  GLAGKPGVPGER------GLPGAHGPPGP---TGPKGEPGFTGRP---GGPGVAGALGQK 447
            GL G PG PG +      G PG  GPPGP   +GP G PG  G P   GG G  G  G  
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 448  GDLGLPGQPGLRGPS--------------GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG 493
            G+ G PGQ G+ GP+              G PGL G +G  G  GLPG+ G PGLPGP G
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223

Query: 494  E-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLP----- 547
            E G  G PG  GP GPPG PG P + GP G PGP GPPG PG     G+ G   P     
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPG 1282

Query: 548  NGGVEGAVLGKGGKPQFGL 566
            NGG++G    KG   Q GL
Sbjct: 1283 NGGIKGE---KGNPGQPGL 1298



 Score =  454 bits (1169), Expect = e-127
 Identities = 269/578 (46%), Positives = 309/578 (53%), Gaps = 52/578 (8%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP  S G  G  GA+G+   K    M  GP GPP   G      +P       L+G+PG 
Sbjct: 875  GPPGSPGLPGKAGASGFPGTKGEMGMM-GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933

Query: 82   PGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRM-GKAGPPGLPGKVGPPGQP 140
            PG  G +G  G PG PG PG   P L G  G  G PG   + G +GP G  G  G PGQP
Sbjct: 934  PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993

Query: 141  GLRGEPGIRGDQGLRGPPGPPGLPG---PSGI--TIP--GKPGAQGVPGPPGFQGEPGPQ 193
            GL G+PG+ G  G +G PG PG PG   P G+  TI   G PG QGV GPPG  G PG  
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 194  GEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGL----GKPGLDGLPGAPG 249
            G PG PG +G KGD G+   GLPG PG  G PG PG PG  G+    G PGL GLPG PG
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPG 1113

Query: 250  DKGESGPPGVPGPRGEPGAVGPKGPPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRG 305
             KG+ G PG PG  G PG  G  GPPG  G+    G  G  G PG  GP G KG+PG  G
Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173

Query: 306  PPGLIGPTGY---------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL 356
             PG  G  G          G PGLPG  G +G  G+PG+ G+ G PG  GEPG  G  G+
Sbjct: 1174 IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGV 1233

Query: 357  GGPPGLPGSAG--LPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLP 414
             GPPG PGS G  L G +G PGP+G  G  GP G  G+ G +GP GL G  G+ GE+G P
Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNP 1293

Query: 415  GAHGPPGPTGPKGE---PGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPA 471
            G  G PG  G KG+   PG  G PG PG+ G  G  G  G+PG PG++GPSG+PG  GP 
Sbjct: 1294 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353

Query: 472  G------PIGPQGLPGLKGE----------PGLPGPPG----EGRAGEPGTAGPTGPPGV 511
            G      P GP GLPG  G+          PG+PG PG     G  G  G  GPTGPPG 
Sbjct: 1354 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1413

Query: 512  PGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
            PG  G+ G  G  G  G PG PG     G+ G   P+G
Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1451



 Score =  451 bits (1159), Expect = e-126
 Identities = 266/545 (48%), Positives = 290/545 (53%), Gaps = 59/545 (10%)

Query: 45   QPMQKGPVGPPFREGKGQYLEMPLPLLPMDL-----KGEPGPPGKPGPRGPPGPPGFPGK 99
            QP   GP G    +G+      P P+ P  L     KGEPG PG PG  GP G  G PG 
Sbjct: 930  QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 100  PGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPG 159
            PG  +PGL GQPG  GPPG    G  G PG PG +GPPG  G  G+ G  G QG+ GPPG
Sbjct: 990  PG--QPGLSGQPGLPGPPG--PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG 1045

Query: 160  PPGLPGPSGITIPGKPGAQG-----------VPGPPGFQGEPGPQGEPGPPGDRGLKGDN 208
            P G+PG  G   PG PG +G           +PG PG +GEPG  G PG PG +G  GD 
Sbjct: 1046 PSGVPGQPGS--PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 209  GV-GQPGLPGAPGQGGAPGPPGLPGPAG----LGKPGLDGLPGAPGDKGESGPPGVPGPR 263
            G+ G PG PGA GQ G PG PG PGP G     G PG  GLPG PG  G  G PG PGP 
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 264  GE---------PGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG 314
            GE         PG  G KG PG  G G PG  GLPG  G  G  G PG  G PGL GP G
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223

Query: 315  Y-GMPGLPGPKGDRGPAGVPG--LLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGR 371
              G  G PG +G  GP G PG  L G +G PG  G PG  GP G  G PG  G  GLPG 
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGN 1283

Query: 372  RGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPG------------VPGERGLPGAHGP 419
             G  G KG  G  G PG+PG++GDQGP GL G PG            +PG  G PG  GP
Sbjct: 1284 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1343

Query: 420  ---PGPTGPKGEPGFTGRPGGPGVAGALGQ----KGDLGLPGQPGLRGPSGIPGLQGPAG 472
               PG  GP+GEPG  G PG PG+ G  GQ    KGD G PG PG  G  G+PG QGP G
Sbjct: 1344 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1403

Query: 473  PIGPQGLPGLKGEPGLPGPPGEG-RAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG 531
              GP G PG  G  GLPG  G G R G+PG  G  G  G+ G PG  G  GPPGPPG   
Sbjct: 1404 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1463

Query: 532  APGAF 536
                F
Sbjct: 1464 VAHGF 1468



 Score =  439 bits (1128), Expect = e-123
 Identities = 279/615 (45%), Positives = 318/615 (51%), Gaps = 110/615 (17%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVG-----PPFREGKGQYLEMPLPLLPM--- 73
            GP+   G  GA GA G+       P  KG  G     P  +  KG+      P LP    
Sbjct: 524  GPKGLPGIPGAPGAPGF-------PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576

Query: 74   -----DLKGEPGPPGKPG------PRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPG 118
                  L G PGP G+PG       RGPPG PG PG PG    MG PG  G PGP G  G
Sbjct: 577  TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKG 635

Query: 119  FSRM-GKAGPPGLPGKVGPPGQ-------PGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT 170
               + G  G PG+PG  G PGQ       PGL G PG  GD GL G PG PG PG  GI 
Sbjct: 636  IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 171  -IPGKPGAQGV-----PGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQG- 222
               G+PG  G+     PGP GF G PGP G PG PG  GL+G  G  G PG  G PG   
Sbjct: 696  GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 223  -GAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGA---VGPKGPPGV 277
             G PGPPGLPG  G LG  G  G PG PG  G +G  G+PGP+G+ G     GP GPPG+
Sbjct: 756  PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 278  DGVGV---PGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGL--PGPKGDRGPAGV 332
             G+GV   PG  G+PGP G  G  G PG +G PG         PGL  PGP G+RG  G+
Sbjct: 816  PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG--------PPGLDVPGPPGERGSPGI 867

Query: 333  PGLLGDRGEPGEDGEPGE---------QGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGP 383
            PG  G  G PG  G PG+         +G  G+ GPPG PG  G+PGR G PG KG+ G 
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 384  GGPPGVPGIRGDQGPSGLAGKPGVP-----------GERGLPGAHGPPGPTGPKGEPGFT 432
             G PG+PG  G++G  G  G PG P           GE+G PG  G PG +GPKG  G  
Sbjct: 928  QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987

Query: 433  GRPGGPGVA------GALGQKGDLGLPGQPGLRGPSGI---------PGLQGPAGPIGPQ 477
            G PG PG++      G  G KG+ GLPGQPGL GP G+         PG QG  GP GP 
Sbjct: 988  GDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS 1047

Query: 478  GLPGLKGEPGLPGPPGE---------GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPG 528
            G+PG  G PGLPG  G+         G  G PG  G  G PG PG+PGI G  G PG PG
Sbjct: 1048 GVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 529  PPGAPGAFDETGIAG 543
             PG PGA  + G+ G
Sbjct: 1108 LPGTPGAKGQPGLPG 1122



 Score =  424 bits (1090), Expect = e-118
 Identities = 281/669 (42%), Positives = 320/669 (47%), Gaps = 174/669 (26%)

Query: 48  QKGPVGPPFREGKGQYLEMPLPLLPMDLKGE------PGPPGKPGPRGPPGPPGFPGKPG 101
           +KG  G P  EG       P P  P   +G+      PGPPG  G RGPPG PGFPG PG
Sbjct: 46  EKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPG 105

Query: 102 M-GKPGLHGQPGPAGPPGFSRM-------GKAGPPGLPGKVGPPGQPGLRGEPGI----- 148
           + G PG  G PGP G PG +         G  G PGL G  GPPG PG++GEPG      
Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSS 165

Query: 149 ----RGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGL 204
               +G+ G  GPPG  GLPGP+GI     PG  G PGPPG  G PGP G PGP G+ GL
Sbjct: 166 LPGPKGNPGYPGPPGIQGLPGPTGI-----PGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220

Query: 205 --------KGDNGV-GQPGLPGAPGQGGAP-------GPPGLPGPAGL-GKPGLDGLPGA 247
                   KG+ G+ G PG PG   +   P       G  GLPG  G  G PG+ G PG 
Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280

Query: 248 PG-DKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGTRG 305
           PG +KGE G  G PG RG+PG  G  G PG+ G+ G PG  G PG  G  G KG+ G  G
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 306 PPGLIGP---TGY--------GMPGLPGPKGDRGPAGV---PGLLGDRGE---------- 341
           PPGL+ P   TG         G+PGLPG KG+RG  G+   PGL G  G           
Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400

Query: 342 -PGEDGEPGEQGPQGLG--GPPGLPGSAGLPGRRGPPGPKG----------EAGPGGPPG 388
            PGE G+ G++GP G+   GPPGL G  G PG  GPPGP G          E GP GPPG
Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG 460

Query: 389 VPGIRGDQGPSGLAGKPG-------------VPGERGLPGAHGPPGP------------- 422
            PG +G QG  G+ G  G              PG+ GLPG  GPPG              
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 423 --TGPKGEPGFTGRPGGPGVAGALGQKGDL-------------------GLPGQPGLRGP 461
             TGPKG PG  G PG PG  G+ G+ GD+                   GLPG PG  G 
Sbjct: 521 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQ 580

Query: 462 SGIPGLQGPAG------------PIGPQGLPGLKGEPGLPGPPG---------------E 494
            G+PGL GP G            P G  GLPGL G  G  GPPG                
Sbjct: 581 DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA 640

Query: 495 GRAGEPGTAGPTGPPGV----PGSPGI------------TGPPGPPGPPGPPGAPGAFDE 538
           G  G+PG  GP G PG     PG PG+             G PG PG PG PG PG+  E
Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 539 TGIAGLHLP 547
            GI G+ LP
Sbjct: 701 PGIPGIGLP 709



 Score =  420 bits (1080), Expect = e-117
 Identities = 269/602 (44%), Positives = 320/602 (53%), Gaps = 100/602 (16%)

Query: 23  GPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPP 82
           GP+ + G    G  G    + +Q    GP GPP     GQ  E   P+   D++ + G  
Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQ----GPPGPP-----GQISEQKRPI---DVEFQKGDQ 260

Query: 83  GKPGPRGPPGPPGFPGKPG-----MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPP 137
           G PG RGPPGPPG  G PG      G+ G  G+PG  G PG  + G+ G PG+PG  G P
Sbjct: 261 GLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG--KDGENGQPGIPGLPGDP 318

Query: 138 GQPGLRGEPGIRGDQGLRGPPGPPGLPGP---SGITI--------PGKPGAQGVPGPPGF 186
           G PG  G  G +G +G  GPPGPPGL  P   +GITI        PG PG +G  G PG 
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378

Query: 187 QGEPG-----------PQGEPGPPGDRGLKGDNG---VGQPGLPGAPGQGGAPGPPGLPG 232
           QG PG           P G PG PG+RG KGD G   +  PG PG  GQ GAPG PG PG
Sbjct: 379 QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438

Query: 233 PAG--------LGKPGLDGLPGAPGDKGESGPPGVPGPRGEP-------GAVGPKGPPGV 277
           PAG        + +PG  G PG+PGDKG  G  GV G +G+        G  GP G PG+
Sbjct: 439 PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGL 498

Query: 278 DGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPA-GVPGL 335
            G+ G PG+ G PG +G  G  G  G +G PG+  P   G PG PG KG+ G     PG+
Sbjct: 499 PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI--PGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 336 LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP---KGEAGPGGPPGVPGI 392
            GD+GE G  G PG  G  G  G  GLPG   LPG +G PG    KGE GP G PG+PG+
Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPG---LPGPKGEPGGITFKGERGPPGNPGLPGL 613

Query: 393 RGDQGPSGLAG--KPGVPGERGLPGAHGPPGPTG---PKGEPGFT-GRPGGPGVAGALGQ 446
            G+ GP G  G   PG  GE+G+ G  G PG  G   PKG+PG T  +PG PG+ G  G+
Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR 673

Query: 447 KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPT 506
            GD+GLPG PGL G  G+PG+            PG KGEPG+PG       G PG  GP 
Sbjct: 674 DGDVGLPGDPGLPGQPGLPGI------------PGSKGEPGIPG------IGLPGPPGPK 715

Query: 507 GPPGVPGSPGITGPPGP---PGPPGPPGAPGAFDETGIA--GLHLPNG--GVEGAVLGKG 559
           G PG+PG PG  G PG     GPPGPPG PG   E G A  G   P G  G +GA+  KG
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 560 GK 561
            +
Sbjct: 776 DR 777



 Score =  385 bits (989), Expect = e-107
 Identities = 241/526 (45%), Positives = 272/526 (51%), Gaps = 88/526 (16%)

Query: 107 LHGQPGPAGPP-GFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP----- 160
           L GQP  A    G S   K    G+ G+ G  G PGL G PG+ G  G  GPPGP     
Sbjct: 19  LWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKG 78

Query: 161 ----PGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQ 212
               PG PGP GI     +PG PG  G+PG PG  G PGPQG PG  G +G +     G 
Sbjct: 79  DDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGER-----GF 133

Query: 213 PGLPGAPGQGGAPGPPGLPGPAGLGKPG---LDGLPGAPGDKGESGPPGV---PGPRGEP 266
           PG PG PG  G PGPPG+PG    G+PG   +  LPG  G+ G  GPPG+   PGP G P
Sbjct: 134 PGSPGFPGLQGPPGPPGIPGMK--GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP 191

Query: 267 GAVGPKGPPGVDGVGVPGAAGLPGP--------QGPSGAKGEPGTRGPPGLIGPTG---- 314
           G +GP GPPG+  +G PG  GLPGP        QGP G KGE G +GPPG  G       
Sbjct: 192 GPIGPPGPPGL--MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKR 249

Query: 315 ----------YGMP---GLPGPKGDRGPAGVP----GLLGDRGEPGEDGEPGEQGPQGLG 357
                      G+P   G PGP G RGP G P    G  G++GEPG+ G+PG+ G  G  
Sbjct: 250 PIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309

Query: 358 GPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGI----------RGDQGPSGLAGKPGV 407
           G PGLPG  G PG  G  G KG+ G  GPPG PG+           G++G  GL G PG 
Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 408 PGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLG-----LPGQPGLRGPS 462
            GERG PG  GPPG  GP G     G PG PG  G  GQKGD G     +PG PGL G  
Sbjct: 370 KGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 463 GIPGLQGPAGPIGPQGLPGLK-GEPGLPGPPG----EGRAGEPGTAGPTGP-------PG 510
           G PGL GP GP GP   P  +  EPG PGPPG    +G  GE G  G  G         G
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG 488

Query: 511 VPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGA 554
           + G PG  G PG PGPPG  G PG   E G AG   P G  G+ GA
Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534



 Score =  259 bits (661), Expect = 8e-69
 Identities = 164/370 (44%), Positives = 185/370 (50%), Gaps = 61/370 (16%)

Query: 246 GAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRG 305
           G  G+KGE G PG+ G  G PG  GP+GPPG  G    G  G+PGP GP G +G PG  G
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQ--KGDDGIPGPPGPKGIRGPPGLPG 99

Query: 306 PPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS 365
            PG  G     +PG+PG  G  GP G+PG  G +GE G  G PG  G QG  GPPG+PG 
Sbjct: 100 FPGTPG-----LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154

Query: 366 AGLPGR---RGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGP 422
            G PG       PGPKG  G  GPPG+ G+ G  G  G  G PG PG  G PG  G PGP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 423 TG--------PKGEPGFTGRPGGPGVAGALG----------QKGDLGLPGQPGLRGPSGI 464
            G        PKGE G  G  G PG  G +           QKGD GLPG    RGP G 
Sbjct: 215 KGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD---RGPPGP 271

Query: 465 PGLQGPAGPIGPQ-GLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPG 522
           PG++GP GP G + G  G +GEPG  G PG +G  G+PG  G  G PG PG PG  G  G
Sbjct: 272 PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 523 PPG---PPGP----------------------PGAPGAFDETGIAGLHLPNG--GVEG-A 554
             G   PPGP                      PG PG   E G  G+  P G  G  G A
Sbjct: 332 QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 555 VLGKGGKPQF 564
           V+G  G P F
Sbjct: 392 VMGPPGPPGF 401



 Score =  156 bits (395), Expect = 5e-38
 Identities = 93/201 (46%), Positives = 102/201 (50%), Gaps = 17/201 (8%)

Query: 383 PGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAG 442
           PG      GI+G++G  G  G  G PG  G PG  GPPGP G KG+ G  G PG  G+ G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 443 ALGQKGDLGLPGQPGL------RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EG 495
             G  G  G PG PG+       GP GIPG  G  G  G  G PG  G  G PGPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 496 RAGEPGT------AGPTGPPGVPGSPGITGPPGP---PGPPGPPGAPGAFDETGIAGLHL 546
             GEPG+       GP G PG PG PGI G PGP   PGP GPPG PG     G  GL  
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 547 PNGGVEGAVLG-KGGKPQFGL 566
           P G +     G KG K + GL
Sbjct: 214 PKGNMGLNFQGPKGEKGEQGL 234



 Score =  148 bits (373), Expect = 2e-35
 Identities = 97/224 (43%), Positives = 108/224 (48%), Gaps = 30/224 (13%)

Query: 375 PGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAH---------GPPGP--- 422
           PG K +    G  G  G RG  G  G  G PG PG  G PG           GPPGP   
Sbjct: 34  PGSKCDCS--GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGI 91

Query: 423 TGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI---PGLQGPAGPIGPQGL 479
            GP G PGF G PG PG+ G  G  G  G+PG  G +G  G    PG  G  GP GP G+
Sbjct: 92  RGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 480 PGLKGEPG------LPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA 532
           PG+KGEPG      LPGP G  G  G PG  G  GP G+PG  G  GPPG  GPPGPPG 
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL 211

Query: 533 PGAFDETGIAGLHLPNGGV-EGAVLGKGGKPQFGLGELSAHATP 575
           PG     G+     P G   E  + G  G P    G++S    P
Sbjct: 212 PGPKGNMGL-NFQGPKGEKGEQGLQGPPGPP----GQISEQKRP 250


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  469 bits (1208), Expect = e-132
 Identities = 279/578 (48%), Positives = 316/578 (54%), Gaps = 88/578 (15%)

Query: 49   KGPVGPP-FREGKGQY-LEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM---- 102
            +GP GPP F   KG+    +P P  P  L G  G  G  G RG PGPPG PG+ G+    
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 103  ---GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGL----- 154
               G  G +GQPGP GPPG   +G  GPPG PG  GP GQPGL G PG +GD G      
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 155  ------RGPPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGPQGEPGP------ 198
                  RG PG PG PGP G      +PGK GA G PG  G  G  GP G PGP      
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 199  PGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAG------------LGKPGLDGLP 245
             G  GLKGD+G+ GQPGLPG  G+ G+ G PGLPGP G             G+PGL G+P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 246  GAPGDKG---------------ESGPPGVPGPRGEPGAVGPKG---PPGVDG----VGVP 283
            G  G KG               + G PG PGP+G PG  G  G   PPG+ G    +G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 284  GAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG------YGMPGLPGPKGDRGPAGVPGLLG 337
            G  G+ GP GPSG  G+PG+ G PG  G  G       G+PGLPGPKG+ G  G PG  G
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 338  DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
             +G  G+ G PG  G  G  G PGLPG    PG  GPPGPKG +GP G PG+PG  G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPG---FPGTPGPPGPKGISGPPGNPGLPGEPGPVG 1152

Query: 398  PSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTG--RPGGPGVAGALGQKGDLGL--- 452
              G  G+PG PGE+G PG  G PGP G KGEPG  G   PG PG+ G  GQKGD GL   
Sbjct: 1153 GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGI 1212

Query: 453  PGQPGLRGPS------GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPT 506
            PG PGL GP       G PG+QGP GP G  G P L+G  G PGP  +G  G PG  GP 
Sbjct: 1213 PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGP--QGPPGRPGLPGPE 1269

Query: 507  GPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGL 544
            GPPG+PG+ GI G  G PG PG PG PG   + G  GL
Sbjct: 1270 GPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1307



 Score =  462 bits (1189), Expect = e-130
 Identities = 284/614 (46%), Positives = 321/614 (52%), Gaps = 100/614 (16%)

Query: 46   PMQKGPVGPPFREGKGQY--LEMPLPLLPMDLKGEPGPPGKPGP------RGPPGPPGFP 97
            P Q G  G P  +G+     + +P P  P    G PGPPG PG        GPPGPPGFP
Sbjct: 686  PGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745

Query: 98   GKPGMGKPGLHGQPGPAGPPGFS-RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRG 156
            G  G     L G PGP G PGF   +G  G  G PG  GPPG+ GL G PG +GD G  G
Sbjct: 746  GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 157  PPGPPGLPGPSGITIPGKPGAQGVPGP---------PGFQGEPGPQG--EPGPPGDRGLK 205
             PGP G PG  GI + G PG  G+PGP         PG +G+PGP G   PGPPG+RG  
Sbjct: 806  QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 206  GDNG----VGQPGLPGAPGQGGAPGPPGL---------PGPAG-LGKPGLDGLPGAPGDK 251
            G  G    +G PG PG PG+ GA G PG          PGP G LG PG  G+PG  GD 
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925

Query: 252  GESGPPGVPGPRGEPGAVGPKGPPGVDGV------------GVPGAAGLPGPQGPSGAKG 299
            G  G PG+PGP GE G+ G  G PG  G             G PG  G+PG  GP G +G
Sbjct: 926  GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQG 985

Query: 300  EPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGP 359
             PG  G PGL G  G  +PG PGPKG+ G  G PGL+G  G  G  G+ G  GPQG+ GP
Sbjct: 986  LPGDPGQPGLSGQPG--LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043

Query: 360  PG------LPGSAGLPGRRGP--------------PGPKGEAGPGGPPGVPGIRGDQGPS 399
            PG       PGS GLPG++G               PGPKGE G  G PG PGI+G  G  
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 400  GLAGKPGVPGER------GLPGAHGPPGP---TGPKGEPGFTGRP---GGPGVAGALGQK 447
            GL G PG PG +      G PG  GPPGP   +GP G PG  G P   GG G  G  G  
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 448  GDLGLPGQPGLRGPS--------------GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG 493
            G+ G PGQ G+ GP+              G PGL G +G  G  GLPG+ G PGLPGP G
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223

Query: 494  E-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVE 552
            E G  G PG  GP GPPG PG P + GP G PGP GPPG PG     G  GL   NGG++
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGLPGPEGPPGLP-GNGGIK 1281

Query: 553  GAVLGKGGKPQFGL 566
            G    KG   Q GL
Sbjct: 1282 GE---KGNPGQPGL 1292



 Score =  454 bits (1169), Expect = e-127
 Identities = 268/562 (47%), Positives = 303/562 (53%), Gaps = 48/562 (8%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP  S G  G  GA+G+   K    M  GP GPP   G      +P       L+G+PG 
Sbjct: 875  GPPGSPGLPGKAGASGFPGTKGEMGMM-GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933

Query: 82   PGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRM-GKAGPPGLPGKVGPPGQP 140
            PG  G +G  G PG PG PG   P L G  G  G PG   + G +GP G  G  G PGQP
Sbjct: 934  PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993

Query: 141  GLRGEPGIRGDQGLRGPPGPPGLPG---PSGI--TIP--GKPGAQGVPGPPGFQGEPGPQ 193
            GL G+PG+ G  G +G PG PG PG   P G+  TI   G PG QGV GPPG  G PG  
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 194  GEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGL----GKPGLDGLPGAPG 249
            G PG PG +G KGD G+   GLPG PG  G PG PG PG  G+    G PGL GLPG PG
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPG 1113

Query: 250  DKGESGPPGVPGPRGEPGAVGPKGPPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRG 305
             KG+ G PG PG  G PG  G  GPPG  G+    G  G  G PG  GP G KG+PG  G
Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173

Query: 306  PPGLIGPTGY---------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL 356
             PG  G  G          G PGLPG  G +G  G+PG+ G+ G PG  GEPG  G  G+
Sbjct: 1174 IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGV 1233

Query: 357  GGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA 416
             GPPG PGS G        GPKG  GP GPPG PG+ G +GP GL G  G+ GE+G PG 
Sbjct: 1234 QGPPGPPGSPG----PALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQ 1289

Query: 417  HGPPGPTGPKGE---PGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGP 473
             G PG  G KG+   PG  G PG PG+ G  G  G  G+PG PG++GPSG+PG    AGP
Sbjct: 1290 PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG---SAGP 1346

Query: 474  IGPQGLPGLKGEPGLPGPPGE-----------GRAGEPGTAGPTGPPGVPGSPGITGPPG 522
             G  GL G  G PGLPGP G+           G  G+PG  G  GP G  G PG TGPPG
Sbjct: 1347 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1406

Query: 523  PPGPPGPPGAPGAFDETGIAGL 544
             PG  G PG  GA    G  GL
Sbjct: 1407 DPGRNGLPGFDGAGGRKGDPGL 1428



 Score =  439 bits (1128), Expect = e-123
 Identities = 279/615 (45%), Positives = 318/615 (51%), Gaps = 110/615 (17%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVG-----PPFREGKGQYLEMPLPLLPM--- 73
            GP+   G  GA GA G+       P  KG  G     P  +  KG+      P LP    
Sbjct: 524  GPKGLPGIPGAPGAPGF-------PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576

Query: 74   -----DLKGEPGPPGKPG------PRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPG 118
                  L G PGP G+PG       RGPPG PG PG PG    MG PG  G PGP G  G
Sbjct: 577  TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKG 635

Query: 119  FSRM-GKAGPPGLPGKVGPPGQ-------PGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT 170
               + G  G PG+PG  G PGQ       PGL G PG  GD GL G PG PG PG  GI 
Sbjct: 636  IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 171  -IPGKPGAQGV-----PGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQG- 222
               G+PG  G+     PGP GF G PGP G PG PG  GL+G  G  G PG  G PG   
Sbjct: 696  GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 223  -GAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGA---VGPKGPPGV 277
             G PGPPGLPG  G LG  G  G PG PG  G +G  G+PGP+G+ G     GP GPPG+
Sbjct: 756  PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 278  DGVGV---PGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGL--PGPKGDRGPAGV 332
             G+GV   PG  G+PGP G  G  G PG +G PG         PGL  PGP G+RG  G+
Sbjct: 816  PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG--------PPGLDVPGPPGERGSPGI 867

Query: 333  PGLLGDRGEPGEDGEPGE---------QGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGP 383
            PG  G  G PG  G PG+         +G  G+ GPPG PG  G+PGR G PG KG+ G 
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 384  GGPPGVPGIRGDQGPSGLAGKPGVP-----------GERGLPGAHGPPGPTGPKGEPGFT 432
             G PG+PG  G++G  G  G PG P           GE+G PG  G PG +GPKG  G  
Sbjct: 928  QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987

Query: 433  GRPGGPGVA------GALGQKGDLGLPGQPGLRGPSGI---------PGLQGPAGPIGPQ 477
            G PG PG++      G  G KG+ GLPGQPGL GP G+         PG QG  GP GP 
Sbjct: 988  GDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS 1047

Query: 478  GLPGLKGEPGLPGPPGE---------GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPG 528
            G+PG  G PGLPG  G+         G  G PG  G  G PG PG+PGI G  G PG PG
Sbjct: 1048 GVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 529  PPGAPGAFDETGIAG 543
             PG PGA  + G+ G
Sbjct: 1108 LPGTPGAKGQPGLPG 1122



 Score =  424 bits (1090), Expect = e-118
 Identities = 281/669 (42%), Positives = 320/669 (47%), Gaps = 174/669 (26%)

Query: 48  QKGPVGPPFREGKGQYLEMPLPLLPMDLKGE------PGPPGKPGPRGPPGPPGFPGKPG 101
           +KG  G P  EG       P P  P   +G+      PGPPG  G RGPPG PGFPG PG
Sbjct: 46  EKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPG 105

Query: 102 M-GKPGLHGQPGPAGPPGFSRM-------GKAGPPGLPGKVGPPGQPGLRGEPGI----- 148
           + G PG  G PGP G PG +         G  G PGL G  GPPG PG++GEPG      
Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSS 165

Query: 149 ----RGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGL 204
               +G+ G  GPPG  GLPGP+GI     PG  G PGPPG  G PGP G PGP G+ GL
Sbjct: 166 LPGPKGNPGYPGPPGIQGLPGPTGI-----PGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220

Query: 205 --------KGDNGV-GQPGLPGAPGQGGAP-------GPPGLPGPAGL-GKPGLDGLPGA 247
                   KG+ G+ G PG PG   +   P       G  GLPG  G  G PG+ G PG 
Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280

Query: 248 PG-DKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGTRG 305
           PG +KGE G  G PG RG+PG  G  G PG+ G+ G PG  G PG  G  G KG+ G  G
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 306 PPGLIGP---TGY--------GMPGLPGPKGDRGPAGV---PGLLGDRGE---------- 341
           PPGL+ P   TG         G+PGLPG KG+RG  G+   PGL G  G           
Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400

Query: 342 -PGEDGEPGEQGPQGLG--GPPGLPGSAGLPGRRGPPGPKG----------EAGPGGPPG 388
            PGE G+ G++GP G+   GPPGL G  G PG  GPPGP G          E GP GPPG
Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG 460

Query: 389 VPGIRGDQGPSGLAGKPG-------------VPGERGLPGAHGPPGP------------- 422
            PG +G QG  G+ G  G              PG+ GLPG  GPPG              
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 423 --TGPKGEPGFTGRPGGPGVAGALGQKGDL-------------------GLPGQPGLRGP 461
             TGPKG PG  G PG PG  G+ G+ GD+                   GLPG PG  G 
Sbjct: 521 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQ 580

Query: 462 SGIPGLQGPAG------------PIGPQGLPGLKGEPGLPGPPG---------------E 494
            G+PGL GP G            P G  GLPGL G  G  GPPG                
Sbjct: 581 DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA 640

Query: 495 GRAGEPGTAGPTGPPGV----PGSPGI------------TGPPGPPGPPGPPGAPGAFDE 538
           G  G+PG  GP G PG     PG PG+             G PG PG PG PG PG+  E
Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 539 TGIAGLHLP 547
            GI G+ LP
Sbjct: 701 PGIPGIGLP 709



 Score =  420 bits (1080), Expect = e-117
 Identities = 269/602 (44%), Positives = 320/602 (53%), Gaps = 100/602 (16%)

Query: 23  GPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPP 82
           GP+ + G    G  G    + +Q    GP GPP     GQ  E   P+   D++ + G  
Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQ----GPPGPP-----GQISEQKRPI---DVEFQKGDQ 260

Query: 83  GKPGPRGPPGPPGFPGKPG-----MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPP 137
           G PG RGPPGPPG  G PG      G+ G  G+PG  G PG  + G+ G PG+PG  G P
Sbjct: 261 GLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG--KDGENGQPGIPGLPGDP 318

Query: 138 GQPGLRGEPGIRGDQGLRGPPGPPGLPGP---SGITI--------PGKPGAQGVPGPPGF 186
           G PG  G  G +G +G  GPPGPPGL  P   +GITI        PG PG +G  G PG 
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378

Query: 187 QGEPG-----------PQGEPGPPGDRGLKGDNG---VGQPGLPGAPGQGGAPGPPGLPG 232
           QG PG           P G PG PG+RG KGD G   +  PG PG  GQ GAPG PG PG
Sbjct: 379 QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438

Query: 233 PAG--------LGKPGLDGLPGAPGDKGESGPPGVPGPRGEP-------GAVGPKGPPGV 277
           PAG        + +PG  G PG+PGDKG  G  GV G +G+        G  GP G PG+
Sbjct: 439 PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGL 498

Query: 278 DGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPA-GVPGL 335
            G+ G PG+ G PG +G  G  G  G +G PG+  P   G PG PG KG+ G     PG+
Sbjct: 499 PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI--PGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 336 LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP---KGEAGPGGPPGVPGI 392
            GD+GE G  G PG  G  G  G  GLPG   LPG +G PG    KGE GP G PG+PG+
Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPG---LPGPKGEPGGITFKGERGPPGNPGLPGL 613

Query: 393 RGDQGPSGLAG--KPGVPGERGLPGAHGPPGPTG---PKGEPGFT-GRPGGPGVAGALGQ 446
            G+ GP G  G   PG  GE+G+ G  G PG  G   PKG+PG T  +PG PG+ G  G+
Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR 673

Query: 447 KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPT 506
            GD+GLPG PGL G  G+PG+            PG KGEPG+PG       G PG  GP 
Sbjct: 674 DGDVGLPGDPGLPGQPGLPGI------------PGSKGEPGIPG------IGLPGPPGPK 715

Query: 507 GPPGVPGSPGITGPPGP---PGPPGPPGAPGAFDETGIA--GLHLPNG--GVEGAVLGKG 559
           G PG+PG PG  G PG     GPPGPPG PG   E G A  G   P G  G +GA+  KG
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 560 GK 561
            +
Sbjct: 776 DR 777



 Score =  399 bits (1025), Expect = e-111
 Identities = 229/462 (49%), Positives = 263/462 (56%), Gaps = 52/462 (11%)

Query: 46   PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP---PGKPGPRGPPGPPGFPGKPGM 102
            P Q G +GPP    KG   +M  P  P  ++G PGP   PG+PG  G PG  G  G PG+
Sbjct: 1014 PGQPGLIGPPGL--KGTIGDMGFPG-PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 103  GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPG 162
               GL G PGP G PG    G  G PG+ G VG PG PGL G PG +G  GL G PG PG
Sbjct: 1071 SSIGLPGLPGPKGEPGLP--GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 163  LPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV----GQPGLPGA 218
             PGP GI+  G PG  G+PG PG  G  G  G+PGPPG++G  G +G+    GQ G PG 
Sbjct: 1129 PPGPKGIS--GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQ 1186

Query: 219  PGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVD 278
            PG G  PGPPGLPG +G  + G  GLPG PG+ G  GP G PG  G PG  GP GPPG  
Sbjct: 1187 PGFGN-PGPPGLPGLSG--QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 279  GVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY----------GMPGLPGPKGDRG 328
            G  + G  G PGPQGP G  G PG  GPPGL G  G           G+PGLPG KGD+G
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1303

Query: 329  PAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPG 388
            P   PGL G+ G PG +G  G+ G  G+ G PG+ G +G+PG  GP G  G  GP GPPG
Sbjct: 1304 P---PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1360

Query: 389  VPG-------IRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVA 441
            +PG       I+GD GP G+   PG PG +GLPG  GP G  GP G PG  GR G PG  
Sbjct: 1361 LPGPSGQSIIIKGDAGPPGI---PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1417

Query: 442  GALGQKGDLGLPGQPG------------LRGPSGIPGLQGPA 471
            GA G+KGD GLPGQPG            L+GP G PG    A
Sbjct: 1418 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459



 Score =  385 bits (989), Expect = e-107
 Identities = 241/526 (45%), Positives = 272/526 (51%), Gaps = 88/526 (16%)

Query: 107 LHGQPGPAGPP-GFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP----- 160
           L GQP  A    G S   K    G+ G+ G  G PGL G PG+ G  G  GPPGP     
Sbjct: 19  LWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKG 78

Query: 161 ----PGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQ 212
               PG PGP GI     +PG PG  G+PG PG  G PGPQG PG  G +G +     G 
Sbjct: 79  DDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGER-----GF 133

Query: 213 PGLPGAPGQGGAPGPPGLPGPAGLGKPG---LDGLPGAPGDKGESGPPGV---PGPRGEP 266
           PG PG PG  G PGPPG+PG    G+PG   +  LPG  G+ G  GPPG+   PGP G P
Sbjct: 134 PGSPGFPGLQGPPGPPGIPGMK--GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP 191

Query: 267 GAVGPKGPPGVDGVGVPGAAGLPGP--------QGPSGAKGEPGTRGPPGLIGPTG---- 314
           G +GP GPPG+  +G PG  GLPGP        QGP G KGE G +GPPG  G       
Sbjct: 192 GPIGPPGPPGL--MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKR 249

Query: 315 ----------YGMP---GLPGPKGDRGPAGVP----GLLGDRGEPGEDGEPGEQGPQGLG 357
                      G+P   G PGP G RGP G P    G  G++GEPG+ G+PG+ G  G  
Sbjct: 250 PIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309

Query: 358 GPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGI----------RGDQGPSGLAGKPGV 407
           G PGLPG  G PG  G  G KG+ G  GPPG PG+           G++G  GL G PG 
Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 408 PGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLG-----LPGQPGLRGPS 462
            GERG PG  GPPG  GP G     G PG PG  G  GQKGD G     +PG PGL G  
Sbjct: 370 KGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 463 GIPGLQGPAGPIGPQGLPGLK-GEPGLPGPPG----EGRAGEPGTAGPTGP-------PG 510
           G PGL GP GP GP   P  +  EPG PGPPG    +G  GE G  G  G         G
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG 488

Query: 511 VPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGA 554
           + G PG  G PG PGPPG  G PG   E G AG   P G  G+ GA
Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534



 Score =  259 bits (661), Expect = 8e-69
 Identities = 164/370 (44%), Positives = 185/370 (50%), Gaps = 61/370 (16%)

Query: 246 GAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRG 305
           G  G+KGE G PG+ G  G PG  GP+GPPG  G    G  G+PGP GP G +G PG  G
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQ--KGDDGIPGPPGPKGIRGPPGLPG 99

Query: 306 PPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS 365
            PG  G     +PG+PG  G  GP G+PG  G +GE G  G PG  G QG  GPPG+PG 
Sbjct: 100 FPGTPG-----LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154

Query: 366 AGLPGR---RGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGP 422
            G PG       PGPKG  G  GPPG+ G+ G  G  G  G PG PG  G PG  G PGP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 423 TG--------PKGEPGFTGRPGGPGVAGALG----------QKGDLGLPGQPGLRGPSGI 464
            G        PKGE G  G  G PG  G +           QKGD GLPG    RGP G 
Sbjct: 215 KGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD---RGPPGP 271

Query: 465 PGLQGPAGPIGPQ-GLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPG 522
           PG++GP GP G + G  G +GEPG  G PG +G  G+PG  G  G PG PG PG  G  G
Sbjct: 272 PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 523 PPG---PPGP----------------------PGAPGAFDETGIAGLHLPNG--GVEG-A 554
             G   PPGP                      PG PG   E G  G+  P G  G  G A
Sbjct: 332 QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 555 VLGKGGKPQF 564
           V+G  G P F
Sbjct: 392 VMGPPGPPGF 401



 Score =  156 bits (395), Expect = 5e-38
 Identities = 93/201 (46%), Positives = 102/201 (50%), Gaps = 17/201 (8%)

Query: 383 PGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAG 442
           PG      GI+G++G  G  G  G PG  G PG  GPPGP G KG+ G  G PG  G+ G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 443 ALGQKGDLGLPGQPGL------RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EG 495
             G  G  G PG PG+       GP GIPG  G  G  G  G PG  G  G PGPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 496 RAGEPGT------AGPTGPPGVPGSPGITGPPGP---PGPPGPPGAPGAFDETGIAGLHL 546
             GEPG+       GP G PG PG PGI G PGP   PGP GPPG PG     G  GL  
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 547 PNGGVEGAVLG-KGGKPQFGL 566
           P G +     G KG K + GL
Sbjct: 214 PKGNMGLNFQGPKGEKGEQGL 234



 Score =  148 bits (373), Expect = 2e-35
 Identities = 97/224 (43%), Positives = 108/224 (48%), Gaps = 30/224 (13%)

Query: 375 PGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAH---------GPPGP--- 422
           PG K +    G  G  G RG  G  G  G PG PG  G PG           GPPGP   
Sbjct: 34  PGSKCDCS--GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGI 91

Query: 423 TGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI---PGLQGPAGPIGPQGL 479
            GP G PGF G PG PG+ G  G  G  G+PG  G +G  G    PG  G  GP GP G+
Sbjct: 92  RGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 480 PGLKGEPG------LPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA 532
           PG+KGEPG      LPGP G  G  G PG  G  GP G+PG  G  GPPG  GPPGPPG 
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL 211

Query: 533 PGAFDETGIAGLHLPNGGV-EGAVLGKGGKPQFGLGELSAHATP 575
           PG     G+     P G   E  + G  G P    G++S    P
Sbjct: 212 PGPKGNMGL-NFQGPKGEKGEQGLQGPPGPP----GQISEQKRP 250


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  461 bits (1185), Expect = e-129
 Identities = 277/584 (47%), Positives = 311/584 (53%), Gaps = 97/584 (16%)

Query: 49   KGPVGPP-FREGKGQY-LEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM---- 102
            +GP GPP F   KG+    +P P  P  L G  G  G  G RG PGPPG PG+ G+    
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 103  ---GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGL----- 154
               G  G +GQPGP GPPG   +G  GPPG PG  GP GQPGL G PG +GD G      
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 155  ------RGPPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGPQGEPGP------ 198
                  RG PG PG PGP G      +PGK GA G PG  G  G  GP G PGP      
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 199  PGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAG------------LGKPGLDGLP 245
             G  GLKGD+G+ GQPGLPG  G+ G+ G PGLPGP G             G+PGL G+P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 246  GAPGDKG---------------ESGPPGVPGPRGEPGAVGPKG---PPGVDG----VGVP 283
            G  G KG               + G PG PGP+G PG  G  G   PPG+ G    +G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 284  GAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG------YGMPGLPGPKGDRGPAGVPGLLG 337
            G  G+ GP GPSG  G+PG+ G PG  G  G       G+PGLPGPKG+ G  G PG  G
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 338  DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
             +G  G+ G PG  G  G  G PGLPG    PG  GPPGPKG +GP G PG+PG  G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPG---FPGTPGPPGPKGISGPPGNPGLPGEPGPVG 1152

Query: 398  PSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTG--RPGGPGVAGALGQKGDLGLPGQ 455
              G  G+PG PGE+G PG  G PGP G KGEPG  G   PG PG+ G  GQKGD GLPG 
Sbjct: 1153 GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGI 1212

Query: 456  PGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG---EGRAGEPGTAGPTGPPGVP 512
            PG       PGL GP G  G  G PG++G PG PG PG   EG  G PG  GP G PG  
Sbjct: 1213 PGN------PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQ 1266

Query: 513  GSPGITGPP------------GPPGPPGPPGAPGAFDETGIAGL 544
            G PG  GPP            G PG PG PG PG   + G  GL
Sbjct: 1267 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1310



 Score =  459 bits (1181), Expect = e-129
 Identities = 284/619 (45%), Positives = 322/619 (52%), Gaps = 107/619 (17%)

Query: 46   PMQKGPVGPPFREGKGQY--LEMPLPLLPMDLKGEPGPPGKPGP------RGPPGPPGFP 97
            P Q G  G P  +G+     + +P P  P    G PGPPG PG        GPPGPPGFP
Sbjct: 686  PGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFP 745

Query: 98   GKPGMGKPGLHGQPGPAGPPGFS-RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRG 156
            G  G     L G PGP G PGF   +G  G  G PG  GPPG+ GL G PG +GD G  G
Sbjct: 746  GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 157  PPGPPGLPGPSGITIPGKPGAQGVPGP---------PGFQGEPGPQG--EPGPPGDRGLK 205
             PGP G PG  GI + G PG  G+PGP         PG +G+PGP G   PGPPG+RG  
Sbjct: 806  QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 206  GDNG----VGQPGLPGAPGQGGAPGPPGL---------PGPAG-LGKPGLDGLPGAPGDK 251
            G  G    +G PG PG PG+ GA G PG          PGP G LG PG  G+PG  GD 
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDD 925

Query: 252  GESGPPGVPGPRGEPGAVGPKGPPGVDGV------------GVPGAAGLPGPQGPSGAKG 299
            G  G PG+PGP GE G+ G  G PG  G             G PG  G+PG  GP G +G
Sbjct: 926  GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQG 985

Query: 300  EPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGP 359
             PG  G PGL G  G  +PG PGPKG+ G  G PGL+G  G  G  G+ G  GPQG+ GP
Sbjct: 986  LPGDPGQPGLSGQPG--LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043

Query: 360  PG------LPGSAGLPGRRGP--------------PGPKGEAGPGGPPGVPGIRGDQGPS 399
            PG       PGS GLPG++G               PGPKGE G  G PG PGI+G  G  
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 400  GLAGKPGVPGER------GLPGAHGPPGP---TGPKGEPGFTGRP---GGPGVAGALGQK 447
            GL G PG PG +      G PG  GPPGP   +GP G PG  G P   GG G  G  G  
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 448  GDLGLPGQPGLRGPS--------------GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG 493
            G+ G PGQ G+ GP+              G PGL G +G  G  GLPG+ G PGLPGP G
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223

Query: 494  E-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLP----- 547
            E G  G PG  GP GPPG PG P + GP G PGP GPPG PG     G+ G   P     
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGF---QGLPGPEGPPGLPG 1279

Query: 548  NGGVEGAVLGKGGKPQFGL 566
            NGG++G    KG   Q GL
Sbjct: 1280 NGGIKGE---KGNPGQPGL 1295



 Score =  452 bits (1164), Expect = e-127
 Identities = 267/562 (47%), Positives = 302/562 (53%), Gaps = 45/562 (8%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP  S G  G  GA+G+   K    M  GP GPP   G      +P       L+G+PG 
Sbjct: 875  GPPGSPGLPGKAGASGFPGTKGEMGMM-GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933

Query: 82   PGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRM-GKAGPPGLPGKVGPPGQP 140
            PG  G +G  G PG PG PG   P L G  G  G PG   + G +GP G  G  G PGQP
Sbjct: 934  PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993

Query: 141  GLRGEPGIRGDQGLRGPPGPPGLPG---PSGI--TIP--GKPGAQGVPGPPGFQGEPGPQ 193
            GL G+PG+ G  G +G PG PG PG   P G+  TI   G PG QGV GPPG  G PG  
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 194  GEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGL----GKPGLDGLPGAPG 249
            G PG PG +G KGD G+   GLPG PG  G PG PG PG  G+    G PGL GLPG PG
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPG 1113

Query: 250  DKGESGPPGVPGPRGEPGAVGPKGPPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRG 305
             KG+ G PG PG  G PG  G  GPPG  G+    G  G  G PG  GP G KG+PG  G
Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173

Query: 306  PPGLIGPTGY---------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL 356
             PG  G  G          G PGLPG  G +G  G+PG+ G+ G PG  GEPG  G  G+
Sbjct: 1174 IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGV 1233

Query: 357  GGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA 416
             GPPG PGS G P   GP G  G  GP G PG  G+ G +GP GL G  G+ GE+G PG 
Sbjct: 1234 QGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ 1292

Query: 417  HGPPGPTGPKGE---PGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGP 473
             G PG  G KG+   PG  G PG PG+ G  G  G  G+PG PG++GPSG+PG    AGP
Sbjct: 1293 PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG---SAGP 1349

Query: 474  IGPQGLPGLKGEPGLPGPPGE-----------GRAGEPGTAGPTGPPGVPGSPGITGPPG 522
             G  GL G  G PGLPGP G+           G  G+PG  G  GP G  G PG TGPPG
Sbjct: 1350 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1409

Query: 523  PPGPPGPPGAPGAFDETGIAGL 544
             PG  G PG  GA    G  GL
Sbjct: 1410 DPGRNGLPGFDGAGGRKGDPGL 1431



 Score =  447 bits (1150), Expect = e-125
 Identities = 267/545 (48%), Positives = 291/545 (53%), Gaps = 62/545 (11%)

Query: 45   QPMQKGPVGPPFREGKGQYLEMPLPLLPMDL-----KGEPGPPGKPGPRGPPGPPGFPGK 99
            QP   GP G    +G+      P P+ P  L     KGEPG PG PG  GP G  G PG 
Sbjct: 930  QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 100  PGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPG 159
            PG  +PGL GQPG  GPPG    G  G PG PG +GPPG  G  G+ G  G QG+ GPPG
Sbjct: 990  PG--QPGLSGQPGLPGPPG--PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG 1045

Query: 160  PPGLPGPSGITIPGKPGAQG-----------VPGPPGFQGEPGPQGEPGPPGDRGLKGDN 208
            P G+PG  G   PG PG +G           +PG PG +GEPG  G PG PG +G  GD 
Sbjct: 1046 PSGVPGQPGS--PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 209  GV-GQPGLPGAPGQGGAPGPPGLPGPAG----LGKPGLDGLPGAPGDKGESGPPGVPGPR 263
            G+ G PG PGA GQ G PG PG PGP G     G PG  GLPG PG  G  G PG PGP 
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP 1163

Query: 264  GE---------PGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG 314
            GE         PG  G KG PG  G G PG  GLPG  G  G  G PG  G PGL GP G
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223

Query: 315  Y-GMPGLPGPKGDRGPAGVPG--LLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGR 371
              G  G PG +G  GP G PG  L G +G PG  G PG  G QGL GP G PG   LPG 
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPG---LPGN 1280

Query: 372  RGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPG------------VPGERGLPGAHGP 419
             G  G KG  G  G PG+PG++GDQGP GL G PG            +PG  G PG  GP
Sbjct: 1281 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1340

Query: 420  ---PGPTGPKGEPGFTGRPGGPGVAGALGQ----KGDLGLPGQPGLRGPSGIPGLQGPAG 472
               PG  GP+GEPG  G PG PG+ G  GQ    KGD G PG PG  G  G+PG QGP G
Sbjct: 1341 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1400

Query: 473  PIGPQGLPGLKGEPGLPGPPGEG-RAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG 531
              GP G PG  G  GLPG  G G R G+PG  G  G  G+ G PG  G  GPPGPPG   
Sbjct: 1401 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1460

Query: 532  APGAF 536
                F
Sbjct: 1461 VAHGF 1465



 Score =  439 bits (1128), Expect = e-123
 Identities = 279/615 (45%), Positives = 318/615 (51%), Gaps = 110/615 (17%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVG-----PPFREGKGQYLEMPLPLLPM--- 73
            GP+   G  GA GA G+       P  KG  G     P  +  KG+      P LP    
Sbjct: 524  GPKGLPGIPGAPGAPGF-------PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576

Query: 74   -----DLKGEPGPPGKPG------PRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPG 118
                  L G PGP G+PG       RGPPG PG PG PG    MG PG  G PGP G  G
Sbjct: 577  TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKG 635

Query: 119  FSRM-GKAGPPGLPGKVGPPGQ-------PGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT 170
               + G  G PG+PG  G PGQ       PGL G PG  GD GL G PG PG PG  GI 
Sbjct: 636  IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 171  -IPGKPGAQGV-----PGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQG- 222
               G+PG  G+     PGP GF G PGP G PG PG  GL+G  G  G PG  G PG   
Sbjct: 696  GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 223  -GAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGA---VGPKGPPGV 277
             G PGPPGLPG  G LG  G  G PG PG  G +G  G+PGP+G+ G     GP GPPG+
Sbjct: 756  PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 278  DGVGV---PGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGL--PGPKGDRGPAGV 332
             G+GV   PG  G+PGP G  G  G PG +G PG         PGL  PGP G+RG  G+
Sbjct: 816  PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG--------PPGLDVPGPPGERGSPGI 867

Query: 333  PGLLGDRGEPGEDGEPGE---------QGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGP 383
            PG  G  G PG  G PG+         +G  G+ GPPG PG  G+PGR G PG KG+ G 
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 384  GGPPGVPGIRGDQGPSGLAGKPGVP-----------GERGLPGAHGPPGPTGPKGEPGFT 432
             G PG+PG  G++G  G  G PG P           GE+G PG  G PG +GPKG  G  
Sbjct: 928  QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987

Query: 433  GRPGGPGVA------GALGQKGDLGLPGQPGLRGPSGI---------PGLQGPAGPIGPQ 477
            G PG PG++      G  G KG+ GLPGQPGL GP G+         PG QG  GP GP 
Sbjct: 988  GDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS 1047

Query: 478  GLPGLKGEPGLPGPPGE---------GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPG 528
            G+PG  G PGLPG  G+         G  G PG  G  G PG PG+PGI G  G PG PG
Sbjct: 1048 GVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 529  PPGAPGAFDETGIAG 543
             PG PGA  + G+ G
Sbjct: 1108 LPGTPGAKGQPGLPG 1122



 Score =  424 bits (1090), Expect = e-118
 Identities = 281/669 (42%), Positives = 320/669 (47%), Gaps = 174/669 (26%)

Query: 48  QKGPVGPPFREGKGQYLEMPLPLLPMDLKGE------PGPPGKPGPRGPPGPPGFPGKPG 101
           +KG  G P  EG       P P  P   +G+      PGPPG  G RGPPG PGFPG PG
Sbjct: 46  EKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPG 105

Query: 102 M-GKPGLHGQPGPAGPPGFSRM-------GKAGPPGLPGKVGPPGQPGLRGEPGI----- 148
           + G PG  G PGP G PG +         G  G PGL G  GPPG PG++GEPG      
Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSS 165

Query: 149 ----RGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGL 204
               +G+ G  GPPG  GLPGP+GI     PG  G PGPPG  G PGP G PGP G+ GL
Sbjct: 166 LPGPKGNPGYPGPPGIQGLPGPTGI-----PGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220

Query: 205 --------KGDNGV-GQPGLPGAPGQGGAP-------GPPGLPGPAGL-GKPGLDGLPGA 247
                   KG+ G+ G PG PG   +   P       G  GLPG  G  G PG+ G PG 
Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280

Query: 248 PG-DKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGTRG 305
           PG +KGE G  G PG RG+PG  G  G PG+ G+ G PG  G PG  G  G KG+ G  G
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 306 PPGLIGP---TGY--------GMPGLPGPKGDRGPAGV---PGLLGDRGE---------- 341
           PPGL+ P   TG         G+PGLPG KG+RG  G+   PGL G  G           
Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400

Query: 342 -PGEDGEPGEQGPQGLG--GPPGLPGSAGLPGRRGPPGPKG----------EAGPGGPPG 388
            PGE G+ G++GP G+   GPPGL G  G PG  GPPGP G          E GP GPPG
Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG 460

Query: 389 VPGIRGDQGPSGLAGKPG-------------VPGERGLPGAHGPPGP------------- 422
            PG +G QG  G+ G  G              PG+ GLPG  GPPG              
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 423 --TGPKGEPGFTGRPGGPGVAGALGQKGDL-------------------GLPGQPGLRGP 461
             TGPKG PG  G PG PG  G+ G+ GD+                   GLPG PG  G 
Sbjct: 521 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQ 580

Query: 462 SGIPGLQGPAG------------PIGPQGLPGLKGEPGLPGPPG---------------E 494
            G+PGL GP G            P G  GLPGL G  G  GPPG                
Sbjct: 581 DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA 640

Query: 495 GRAGEPGTAGPTGPPGV----PGSPGI------------TGPPGPPGPPGPPGAPGAFDE 538
           G  G+PG  GP G PG     PG PG+             G PG PG PG PG PG+  E
Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 539 TGIAGLHLP 547
            GI G+ LP
Sbjct: 701 PGIPGIGLP 709



 Score =  420 bits (1080), Expect = e-117
 Identities = 269/602 (44%), Positives = 320/602 (53%), Gaps = 100/602 (16%)

Query: 23  GPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPP 82
           GP+ + G    G  G    + +Q    GP GPP     GQ  E   P+   D++ + G  
Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQ----GPPGPP-----GQISEQKRPI---DVEFQKGDQ 260

Query: 83  GKPGPRGPPGPPGFPGKPG-----MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPP 137
           G PG RGPPGPPG  G PG      G+ G  G+PG  G PG  + G+ G PG+PG  G P
Sbjct: 261 GLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG--KDGENGQPGIPGLPGDP 318

Query: 138 GQPGLRGEPGIRGDQGLRGPPGPPGLPGP---SGITI--------PGKPGAQGVPGPPGF 186
           G PG  G  G +G +G  GPPGPPGL  P   +GITI        PG PG +G  G PG 
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378

Query: 187 QGEPG-----------PQGEPGPPGDRGLKGDNG---VGQPGLPGAPGQGGAPGPPGLPG 232
           QG PG           P G PG PG+RG KGD G   +  PG PG  GQ GAPG PG PG
Sbjct: 379 QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438

Query: 233 PAG--------LGKPGLDGLPGAPGDKGESGPPGVPGPRGEP-------GAVGPKGPPGV 277
           PAG        + +PG  G PG+PGDKG  G  GV G +G+        G  GP G PG+
Sbjct: 439 PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGL 498

Query: 278 DGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPA-GVPGL 335
            G+ G PG+ G PG +G  G  G  G +G PG+  P   G PG PG KG+ G     PG+
Sbjct: 499 PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI--PGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 336 LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP---KGEAGPGGPPGVPGI 392
            GD+GE G  G PG  G  G  G  GLPG   LPG +G PG    KGE GP G PG+PG+
Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPG---LPGPKGEPGGITFKGERGPPGNPGLPGL 613

Query: 393 RGDQGPSGLAG--KPGVPGERGLPGAHGPPGPTG---PKGEPGFT-GRPGGPGVAGALGQ 446
            G+ GP G  G   PG  GE+G+ G  G PG  G   PKG+PG T  +PG PG+ G  G+
Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR 673

Query: 447 KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPT 506
            GD+GLPG PGL G  G+PG+            PG KGEPG+PG       G PG  GP 
Sbjct: 674 DGDVGLPGDPGLPGQPGLPGI------------PGSKGEPGIPG------IGLPGPPGPK 715

Query: 507 GPPGVPGSPGITGPPGP---PGPPGPPGAPGAFDETGIA--GLHLPNG--GVEGAVLGKG 559
           G PG+PG PG  G PG     GPPGPPG PG   E G A  G   P G  G +GA+  KG
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 560 GK 561
            +
Sbjct: 776 DR 777



 Score =  385 bits (989), Expect = e-107
 Identities = 241/526 (45%), Positives = 272/526 (51%), Gaps = 88/526 (16%)

Query: 107 LHGQPGPAGPP-GFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP----- 160
           L GQP  A    G S   K    G+ G+ G  G PGL G PG+ G  G  GPPGP     
Sbjct: 19  LWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKG 78

Query: 161 ----PGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQ 212
               PG PGP GI     +PG PG  G+PG PG  G PGPQG PG  G +G +     G 
Sbjct: 79  DDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGER-----GF 133

Query: 213 PGLPGAPGQGGAPGPPGLPGPAGLGKPG---LDGLPGAPGDKGESGPPGV---PGPRGEP 266
           PG PG PG  G PGPPG+PG    G+PG   +  LPG  G+ G  GPPG+   PGP G P
Sbjct: 134 PGSPGFPGLQGPPGPPGIPGMK--GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP 191

Query: 267 GAVGPKGPPGVDGVGVPGAAGLPGP--------QGPSGAKGEPGTRGPPGLIGPTG---- 314
           G +GP GPPG+  +G PG  GLPGP        QGP G KGE G +GPPG  G       
Sbjct: 192 GPIGPPGPPGL--MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKR 249

Query: 315 ----------YGMP---GLPGPKGDRGPAGVP----GLLGDRGEPGEDGEPGEQGPQGLG 357
                      G+P   G PGP G RGP G P    G  G++GEPG+ G+PG+ G  G  
Sbjct: 250 PIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309

Query: 358 GPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGI----------RGDQGPSGLAGKPGV 407
           G PGLPG  G PG  G  G KG+ G  GPPG PG+           G++G  GL G PG 
Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 408 PGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLG-----LPGQPGLRGPS 462
            GERG PG  GPPG  GP G     G PG PG  G  GQKGD G     +PG PGL G  
Sbjct: 370 KGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 463 GIPGLQGPAGPIGPQGLPGLK-GEPGLPGPPG----EGRAGEPGTAGPTGP-------PG 510
           G PGL GP GP GP   P  +  EPG PGPPG    +G  GE G  G  G         G
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG 488

Query: 511 VPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGA 554
           + G PG  G PG PGPPG  G PG   E G AG   P G  G+ GA
Sbjct: 489 ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534



 Score =  259 bits (661), Expect = 8e-69
 Identities = 164/370 (44%), Positives = 185/370 (50%), Gaps = 61/370 (16%)

Query: 246 GAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRG 305
           G  G+KGE G PG+ G  G PG  GP+GPPG  G    G  G+PGP GP G +G PG  G
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQ--KGDDGIPGPPGPKGIRGPPGLPG 99

Query: 306 PPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS 365
            PG  G     +PG+PG  G  GP G+PG  G +GE G  G PG  G QG  GPPG+PG 
Sbjct: 100 FPGTPG-----LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154

Query: 366 AGLPGR---RGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGP 422
            G PG       PGPKG  G  GPPG+ G+ G  G  G  G PG PG  G PG  G PGP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 423 TG--------PKGEPGFTGRPGGPGVAGALG----------QKGDLGLPGQPGLRGPSGI 464
            G        PKGE G  G  G PG  G +           QKGD GLPG    RGP G 
Sbjct: 215 KGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD---RGPPGP 271

Query: 465 PGLQGPAGPIGPQ-GLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPG 522
           PG++GP GP G + G  G +GEPG  G PG +G  G+PG  G  G PG PG PG  G  G
Sbjct: 272 PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 523 PPG---PPGP----------------------PGAPGAFDETGIAGLHLPNG--GVEG-A 554
             G   PPGP                      PG PG   E G  G+  P G  G  G A
Sbjct: 332 QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 555 VLGKGGKPQF 564
           V+G  G P F
Sbjct: 392 VMGPPGPPGF 401



 Score =  156 bits (395), Expect = 5e-38
 Identities = 93/201 (46%), Positives = 102/201 (50%), Gaps = 17/201 (8%)

Query: 383 PGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAG 442
           PG      GI+G++G  G  G  G PG  G PG  GPPGP G KG+ G  G PG  G+ G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 443 ALGQKGDLGLPGQPGL------RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EG 495
             G  G  G PG PG+       GP GIPG  G  G  G  G PG  G  G PGPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 496 RAGEPGT------AGPTGPPGVPGSPGITGPPGP---PGPPGPPGAPGAFDETGIAGLHL 546
             GEPG+       GP G PG PG PGI G PGP   PGP GPPG PG     G  GL  
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213

Query: 547 PNGGVEGAVLG-KGGKPQFGL 566
           P G +     G KG K + GL
Sbjct: 214 PKGNMGLNFQGPKGEKGEQGL 234



 Score =  148 bits (373), Expect = 2e-35
 Identities = 97/224 (43%), Positives = 108/224 (48%), Gaps = 30/224 (13%)

Query: 375 PGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAH---------GPPGP--- 422
           PG K +    G  G  G RG  G  G  G PG PG  G PG           GPPGP   
Sbjct: 34  PGSKCDCS--GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGI 91

Query: 423 TGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI---PGLQGPAGPIGPQGL 479
            GP G PGF G PG PG+ G  G  G  G+PG  G +G  G    PG  G  GP GP G+
Sbjct: 92  RGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 480 PGLKGEPG------LPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA 532
           PG+KGEPG      LPGP G  G  G PG  G  GP G+PG  G  GPPG  GPPGPPG 
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL 211

Query: 533 PGAFDETGIAGLHLPNGGV-EGAVLGKGGKPQFGLGELSAHATP 575
           PG     G+     P G   E  + G  G P    G++S    P
Sbjct: 212 PGPKGNMGL-NFQGPKGEKGEQGLQGPPGPP----GQISEQKRP 250


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  452 bits (1162), Expect = e-127
 Identities = 271/562 (48%), Positives = 299/562 (53%), Gaps = 59/562 (10%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP+ S G  G  G AG    K +     G  G P  +GK        P  P    G PGP
Sbjct: 518  GPKGSPGEAGRPGEAGLPGAKGLT----GSPGSPGPDGKTG------PPGPAGQDGRPGP 567

Query: 82   PGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQP 140
            PG PG RG  G  GFPG  G  G+PG  G+ G  GPPG       GP G  G+ G  G P
Sbjct: 568  PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPG-----AVGPAGKDGEAGAQGPP 622

Query: 141  GLRGEPGIRGDQGLRGPPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPP 199
            G  G  G RG+QG  G PG  GLPGP+G     GKPG QGVPG  G  G  G +GE G P
Sbjct: 623  GPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFP 682

Query: 200  GDRGLKGDNGV-------GQPGLPGAPGQGGAPGPPGLPGPAGL----GKPGLDGLPGAP 248
            G+RG++G  G        G PG  GA G  GAPG PG  G  GL    G+ G  GLPG  
Sbjct: 683  GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPK 742

Query: 249  GDKGESGPPGV---PGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGTR 304
            GD+G++GP G    PG  G  G  GP GPPG  G  G  G +G  GP GP+GA+G PG R
Sbjct: 743  GDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR 802

Query: 305  GPPGLIGPTGY-------------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQ 351
            G PG  GP G+             G PG  G KGD GP G  G  G  G  G  G PG +
Sbjct: 803  GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAK 862

Query: 352  GPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGER 411
            G +G  GPPG  G  G  GR GPPGP G AGP GPPG  G  G +GP G  G  G PGE 
Sbjct: 863  GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV 922

Query: 412  GLPGAHGPPGPTGPKGEPGF---TGRPGGPGVAGALGQKGDLGLPGQ------PGLRGPS 462
            G P   GPPGP G KG PG     G PG PG  G  GQ+G +GLPGQ      PGL GPS
Sbjct: 923  GPP---GPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS 979

Query: 463  GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPP 521
            G PG QGP+G  G +G PG  G PGL GPPGE GR G PG  G  G  G PG+ G  G  
Sbjct: 980  GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039

Query: 522  GPPGPPGPPGAPGAFDETGIAG 543
            GP GPPG PGAPGA    G AG
Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAG 1061



 Score =  440 bits (1132), Expect = e-123
 Identities = 275/643 (42%), Positives = 310/643 (48%), Gaps = 135/643 (20%)

Query: 23   GPRASSGG----GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGE 78
            GP    G     G  GA G A V    P  KG  G P + G+      P  + P    GE
Sbjct: 557  GPAGQDGRPGPPGPPGARGQAGVMGF-PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGE 615

Query: 79   PGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPG 138
             G  G PGP GP G  G  G  G   PG  G PGPAGPPG    GK G  G+PG +G PG
Sbjct: 616  AGAQGPPGPAGPAGERGEQGPAG--SPGFQGLPGPAGPPG--EAGKPGEQGVPGDLGAPG 671

Query: 139  QPGLRGEPGIRGDQGLRGPPGP---------------------PGLPGPSGIT----IPG 173
              G RGE G  G++G++GPPGP                     PG PG  G      +PG
Sbjct: 672  PSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPG 731

Query: 174  KPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGP----- 227
            + GA G+PGP G +G+ GP+G  G PG  G++G  G +G PG  GAPG  G  GP     
Sbjct: 732  ERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAG 791

Query: 228  -------------PGLPGPAGL-GKPGLDGLPGA---PGD---KGESGPPGVPGPRGEPG 267
                         PG PGPAG  G PG DG PGA   PGD   KG++GPPG  GP G PG
Sbjct: 792  PTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG 851

Query: 268  AVGPKGPPGVDGV----------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-YG 316
             +G  G PG  G           G PGAAG  GP GPSG  G PG  GP G  G  G  G
Sbjct: 852  PIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRG 911

Query: 317  MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGE---PGEQGPQGLGGP-------------- 359
              G  G  G+ GP G PG  G++G PG DG    PG  GPQG+ G               
Sbjct: 912  ETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERG 971

Query: 360  -PGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGV---PGERGLPG 415
             PGLPG +G PG++GP G  GE GP GP G PG+ G  G SG  G PG    PG  G PG
Sbjct: 972  FPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPG 1031

Query: 416  AHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIG 475
            A G  G TGP G PG  G PG PG  G  G+ GD G  G  G  GP G  G +GPAGP G
Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091

Query: 476  PQG------------------LPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPG 516
            P+G                    GL+G PG PG PGE G +G  G AGP GPPG  G+PG
Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG 1151

Query: 517  I------------------------TGPPGPPGPPGPPGAPGA 535
                                      GPPGPPGPPGPPG P A
Sbjct: 1152 KDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194



 Score =  431 bits (1107), Expect = e-120
 Identities = 263/561 (46%), Positives = 290/561 (51%), Gaps = 55/561 (9%)

Query: 23  GPRASSGG-GAGGAAGYAPVKYIQPMQ---KGPVGPPFREGKGQYLEMPLPLLPMDLKGE 78
           GP+ +SG  GA G+ G    K  +P     +GP GP   EGK               +GE
Sbjct: 428 GPKGNSGEPGAPGSKGDTGAKG-EPGPVGVQGPPGPAGEEGK------------RGARGE 474

Query: 79  PGP---PGKPGPRGPPGPPGFPGKPGMGKP----GLHGQPGPAGPPGFSRMGKAGPPGLP 131
           PGP   PG PG RG PG  GFPG  G+  P    G  G PGPAGP G       G  G P
Sbjct: 475 PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKG-----SPGEAGRP 529

Query: 132 GKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPG 191
           G+ G PG  GL G PG  G  G  GPPGP G  G  G   PG PGA+G  G  GF G  G
Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGP--PGPPGARGQAGVMGFPGPKG 587

Query: 192 PQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAG-------LGKPGLDGL 244
             GEPG  G+RG+ G  G   P   G  G+ GA GPPG  GPAG        G PG  GL
Sbjct: 588 AAGEPGKAGERGVPGPPGAVGPA--GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGL 645

Query: 245 PGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGT 303
           PG  G  GE+G PG  G  G+ GA GP G  G  G  G  G  G PGP GP GA G PG 
Sbjct: 646 PGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705

Query: 304 RGPPGLIG----PTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGE---DGEPGEQGPQGL 356
            G  G  G    P   G PGL G  G+RG AG+PG  GDRG+ G    DG PG+ G +GL
Sbjct: 706 DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGL 765

Query: 357 GGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA 416
            GP G PG AG PG +G  GP G AGP G  G PG RG+ GP G AG  G PG  G PGA
Sbjct: 766 TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825

Query: 417 HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGP 476
            G PG  G KG+    G PG  G AG  G  G++G PG  G RG +G PG  G  G  G 
Sbjct: 826 KGEPGDAGAKGD---AGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882

Query: 477 QGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAF 536
            G PG  G  G PGPPG   AG+ G  GP G  G  G PG  GPPGPPGP G  G+PGA 
Sbjct: 883 VGPPGPSGNAGPPGPPGP--AGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940

Query: 537 DETGIAGLHLPNG--GVEGAV 555
              G  G   P G  G  G V
Sbjct: 941 GPAGAPGTPGPQGIAGQRGVV 961



 Score =  430 bits (1105), Expect = e-120
 Identities = 289/695 (41%), Positives = 328/695 (47%), Gaps = 165/695 (23%)

Query: 23  GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQY----------------LE 65
           GPR  +G  G  G  G   +    P   GP GPP   G G                  + 
Sbjct: 121 GPRGPAGPPGRDGIPGQPGL----PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGIS 176

Query: 66  MPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP-GLHGQPGPAGPPGFSRMGK 124
           +P P+ P   +G PGPPG PGP+G  GPPG PG+PG   P G  G PGP G  G    G+
Sbjct: 177 VPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDD--GE 234

Query: 125 AGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT-------IPGKPGA 177
           AG PG PG+ GPPG  G RG PG  G  G++G  G  GL G  G          PG PG 
Sbjct: 235 AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294

Query: 178 QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-------------GQPGLPGAPGQGGA 224
            G PG  G +G PG +G PG PG  G +G++G              G PG PGA G  G 
Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGE 354

Query: 225 PGP---------------PGLPGPAGL----GKPGLDGLPGAPGDKGE---SGPPGVPGP 262
            GP               PG PGPAG     G PG DG PGA G  G    +G PG PG 
Sbjct: 355 AGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGA 414

Query: 263 RGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPG---TRGPPGLIGPTGY---- 315
           RG  G  GP GPPG  G    G  G PG +G +GAKGEPG    +GPPG  G  G     
Sbjct: 415 RGPSGPQGPGGPPGPKGNS--GEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472

Query: 316 ---GMPGLPGPKGDRGPAG------VPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSA 366
              G  GLPGP G+RG  G        G+ G +G  GE G PG  GP+G  G  G PG A
Sbjct: 473 GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA 532

Query: 367 GLP---------------GRRGPPGPKGEAGPGGPPGVPGIRGD------QGPSGLAGKP 405
           GLP               G+ GPPGP G+ G  GPPG PG RG        GP G AG+P
Sbjct: 533 GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEP 592

Query: 406 GVPGERGLP---------------GAHGPPGPTGPKGE---------PGFTGRP---GGP 438
           G  GERG+P               GA GPPGP GP GE         PGF G P   G P
Sbjct: 593 GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP 652

Query: 439 GVAGALGQK---GDLGLPGQPGLRGPSGIP---GLQGPAGPIGPQ--------------- 477
           G AG  G++   GDLG PG  G RG  G P   G+QGP GP GP+               
Sbjct: 653 GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712

Query: 478 ---GLPGLKGEPGLPGPPGE-------GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPP 527
              G PG +G PGL G PGE       G  G+ G AGP G  G PG  G+ G  GP GPP
Sbjct: 713 GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772

Query: 528 GPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKP 562
           GP GAPG   E+G +G   P  G  GA  G  G+P
Sbjct: 773 GPAGAPGDKGESGPSGPAGPT-GARGAP-GDRGEP 805



 Score =  342 bits (876), Expect = 9e-94
 Identities = 221/522 (42%), Positives = 238/522 (45%), Gaps = 107/522 (20%)

Query: 146 PGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLK 205
           PG    +G   P  P G   P+     G  G +G  GP G +G  GP G  G PG  GL 
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 206 GDNGVGQPGLPGAPGQG-------------------------------GAPGPPGLPGPA 234
           G    G PG PG PG G                               G PGPPG PGP 
Sbjct: 142 GP--PGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQ 199

Query: 235 GL-GKPGLDGLPGAPGDKGESGPPGVPGPRGE------PGAVGPKGPPGVDGV-GVPGAA 286
           G  G PG  G PGA G  G  GPPG PG  G+      PG  G +GPPG  G  G+PG A
Sbjct: 200 GFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTA 259

Query: 287 GLP------------------GPQGPSGAKGEPGTRGPPGLIGPTGY----GMPGLPGPK 324
           GLP                  GP GP G  G PG  G PG +GP G     G PG PGP 
Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPA 319

Query: 325 GDR------------------GPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSA 366
           G R                  GP G PG +G +GE G  G  G +GPQG+ G PG PG A
Sbjct: 320 GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379

Query: 367 GLPGRRGPPGPKGEAG-------PG--GPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAH 417
           G  G  G PG  G+ G       PG  G PG PG RG  GP G  G PG  G  G PGA 
Sbjct: 380 GAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAP 439

Query: 418 GPPGPTGPKGEPGFTGRPGGPGVA------GALGQKGDLGLPGQPGLR---GPSGIPGLQ 468
           G  G TG KGEPG  G  G PG A      GA G+ G  GLPG PG R   G  G PG  
Sbjct: 440 GSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGAD 499

Query: 469 GPAGPIGPQGLPGLKGEPGLPGPPGE----GRAGEPGTAGPTGPPGVPGSPGITGPPGPP 524
           G AGP GP G  G  G  G  G PGE    G AG PG  G TG PG PG  G TGPPGP 
Sbjct: 500 GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPA 559

Query: 525 GP---PGPPGAPGAFDETGIAGLHLPNGGV-EGAVLGKGGKP 562
           G    PGPPG PGA  + G+ G   P G   E    G+ G P
Sbjct: 560 GQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  448 bits (1152), Expect = e-126
 Identities = 278/632 (43%), Positives = 313/632 (49%), Gaps = 115/632 (18%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQ-----PMQKGPVGPPFREG----KGQYLEM------ 66
            GP+ +SGG G  G  G       Q     P  KGP GPP ++G     GQ  E       
Sbjct: 931  GPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 990

Query: 67   -----PLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFS 120
                 P  + P    GE GP G+ G  GPPGPPG  G PG+ GK G  G PGPAG PG  
Sbjct: 991  GPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPG-- 1048

Query: 121  RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG-------ITIPG 173
               K GPPGL G  G  G PG  G  G++G++G  GPPGP G PG  G       I IPG
Sbjct: 1049 ---KDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105

Query: 174  KPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-------------------VGQPG 214
            +PG QG PGP G +G PG +G  GP G  GL+G  G                   +G+PG
Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165

Query: 215  LPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPG---------DKGESGPPGVPGPRG 264
              G+ G  G  GPPG  GP G +G+PG  G  G PG          KG+ GP G PGP G
Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225

Query: 265  EPGAVGPKGPPGVDG----VGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGL 320
              G  G  GPPG  G    VG  G  G PGP+GPSGA G  G +GPPG     G G PG 
Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPG-----GIGNPGA 1280

Query: 321  PGPKGDRGPAGVPGLLGDRGEPG---EDGEPGEQGPQGLGGPPG------------LPGS 365
             G KG+ G AG PGL G+ G PG   E GE GE GP G  GPPG             PG 
Sbjct: 1281 VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGP 1340

Query: 366  AGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGP 425
             G PG  GPPG  G AG  GPPG  G  G+ G +G  G  G PG  G PG  GPPGP GP
Sbjct: 1341 VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400

Query: 426  KGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI---------------PGLQGP 470
            +G  G  G  G  G+ G  G+ G +G  G PG  GP G+               PG  GP
Sbjct: 1401 EGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460

Query: 471  AGPIGPQGLPGLKGEP------------GLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGI 517
             GP+GP GLPGLKG+             GL GPPGE G  G+ G  GP G  G  G  GI
Sbjct: 1461 PGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGI 1520

Query: 518  TGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
            TGP GP GPPGPPG PG     G  G   P G
Sbjct: 1521 TGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTG 1552



 Score =  427 bits (1097), Expect = e-119
 Identities = 270/620 (43%), Positives = 306/620 (49%), Gaps = 100/620 (16%)

Query: 30   GGAGGAAGYAPVKYIQPMQ------------KGPVGPPFREGKGQYLEMPLPLLPMD--- 74
            GG G A    P+   Q  Q            +GP GP    G+      P P+ P     
Sbjct: 527  GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGR------PGPVGPPGSGG 580

Query: 75   LKGEPGPPGKPGPRGPPGPPGFPGKPGM-------GKPGLHGQPGPAGPPGFSRM----G 123
            LKGEPG  G  GPRG  GPPG  GKPG        G  G+ GQ GP G  GF  +    G
Sbjct: 581  LKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPG 640

Query: 124  KAGPPGLPGKVGPPGQPGLRGE------------PGIRGDQGLRGPPGPPGLPGPSGIT- 170
            + G  G PG  GPPG PG  GE            PG  G +GL GP GPPG PGP G+T 
Sbjct: 641  EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG 700

Query: 171  IPGKPGA------QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGG 223
            + G+PG       QG PGPPG QG PG QG PGP G  G  G+ G +G+PGLPG PG  G
Sbjct: 701  MDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADG 760

Query: 224  APGPPGLPGP----AGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG 279
             PG PG  GP     G G PG  G  G PG +G  G  G+ G +G  G  G  G PG  G
Sbjct: 761  PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG 820

Query: 280  ----------VGVPGAAGLPGPQGPSGA---KGEPGTRGPPGLIGPTGY-GMPGLPGPKG 325
                      +G PG  G  GP+GP G     G+PG  GPPG  G  G  G+PG PG +G
Sbjct: 821  DMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQG 880

Query: 326  DRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385
             +G  G PG  G  GE G  G PG+ GP+G  GP G  G  G  G  G PGPKG +G  G
Sbjct: 881  PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDG 940

Query: 386  PPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGF---TGRPGGPGV-- 440
            P G PG RG  GP G  G PG  G  G PG  G PG  G +GE GF   TG PG PGV  
Sbjct: 941  PAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000

Query: 441  -------AGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG 493
                    G +G++G  G PG PG +G  G+ G +G  G  GP GLPG  G PGL G PG
Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPG 1060

Query: 494  E-------GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGP------PGPPGAPGAFDETG 540
            +       G  G  G  GP GPPG  GSPG  GP G  GP      PGP G PG   E G
Sbjct: 1061 DRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKG 1120

Query: 541  IAGLHLPNG-----GVEGAV 555
              G   P G     G++G V
Sbjct: 1121 APGEKGPQGPAGRDGLQGPV 1140



 Score =  379 bits (973), Expect = e-105
 Identities = 235/514 (45%), Positives = 264/514 (51%), Gaps = 68/514 (13%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP  S G  G  GAAG   +    P + GP GPP   G+        P  P    G  GP
Sbjct: 1084 GPAGSPGERGPAGAAGPIGI----PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP 1139

Query: 82   PGKPGPRGPPGPPGFPGKPG-MGKPGLHGQ---------PGPAGPPGFSRMGKAGPPGLP 131
             G PGP GP GPPG  G  G +G+PG  G          PGP GP G   +G+ GP G  
Sbjct: 1140 VGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQG--PIGQPGPSGAD 1197

Query: 132  GKVGPPGQPGLRGEPGIRGDQGLRGPPGP---PGLPGPSG-------ITIPGKPGAQGVP 181
            G+ GP GQ GL G+ G  G +G  GPPGP    GLPGP G       +   G PG  G  
Sbjct: 1198 GEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPR 1257

Query: 182  GPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAG----- 235
            GP G  G  GPQG PG  G+ G  G+ G  G+ G PG PG+GG PGP G  G  G     
Sbjct: 1258 GPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS 1317

Query: 236  --LGKPGLDGLPGAPGDKGESGP---PGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLP 289
               G PG  G PG  G KG  GP   PG PGP GEPG  G  GPPG  G  G PG  G P
Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377

Query: 290  GPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPG 349
            GP G  G  G PG RGPPG  GP G    G  G KG+ G  G PG  G  G  G  G+PG
Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEG--RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG 1435

Query: 350  EQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGV-- 407
              G +G+ GP G  G  G PG  GPPGP       GPPG+PG++GD GP G  G PG+  
Sbjct: 1436 PDGLRGIPGPVGEQGLPGSPGPDGPPGPM------GPPGLPGLKGDSGPKGEKGHPGLIG 1489

Query: 408  ----PGERGLPGAHGPPGP---TGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
                PGE+G  G  G PGP   +GPKGE G TG P GP           +G PG PGL G
Sbjct: 1490 LIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG-PSGP-----------IGPPGPPGLPG 1537

Query: 461  PSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE 494
            P G  G +G +GP GP+G  G  G PG PGPPGE
Sbjct: 1538 PPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571



 Score =  374 bits (961), Expect = e-103
 Identities = 248/586 (42%), Positives = 274/586 (46%), Gaps = 128/586 (21%)

Query: 79   PGPPGKP-----GPRGPPGPPGFPGKPGMGKPGL--HGQPGPAGPPGFSRMGKAGPPGLP 131
            PG P        G  GP G  G  G+P + +PG+   G PGP GP        AG PG P
Sbjct: 432  PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGP--------AGLPGPP 483

Query: 132  GKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIP------------------- 172
            G +GP GQ G         D G RGPPG PGLPG  G+  P                   
Sbjct: 484  GTMGPTGQVG---------DPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGS 534

Query: 173  ---------------------------------GKPGAQGVPGPPGFQGEP------GPQ 193
                                             G+PG  G PG  G +GEP      GP+
Sbjct: 535  KGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPR 594

Query: 194  GEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGL-------GKPGLDGLP 245
            G  GPPG  G  G  G  G  G  G PGQ G  G  G  G AGL       G PG  G P
Sbjct: 595  GVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPP 654

Query: 246  GAPGDKGESGPPGVPGPRGEP------GAVGPKGPPGVDG-VGVPGAAGLPGPQGPSGAK 298
            G PGD GE G  G  GPRG P      G +GPKGPPG  G  GV G  G PGP+G  G +
Sbjct: 655  GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQ 714

Query: 299  GEP------------GTRGPPGLIGPTG----YGMPGLPGPKGDRGPAGVPGLLGDRGEP 342
            GEP            G  GP G IGP G     G PGLPG  G  GP G PG  G  GE 
Sbjct: 715  GEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEK 774

Query: 343  GEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG-PG--GPPGVPGIRGDQGPS 399
            G  G PG QGP G  GP G+ G+ G+ G +G  G KGE G PG  G  G+ G RG+ GP 
Sbjct: 775  GGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPP 834

Query: 400  GLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGL- 458
            G  G+ G  G +G  G +G PGP GP GE G  G PG PG  G  G KG +G PG PG  
Sbjct: 835  GPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGAN 894

Query: 459  -----RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP----GEGRAGEPGTAGPTGPP 509
                 RG  G PG +G  GP GP+G  G +G  G PGP     G+G AG PG  GP GP 
Sbjct: 895  GEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQ 954

Query: 510  GVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEG 553
            G  G PG  GPPGPPG  G PG PG   ETG  G   P G  GV G
Sbjct: 955  GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000



 Score =  350 bits (897), Expect = 3e-96
 Identities = 218/460 (47%), Positives = 237/460 (51%), Gaps = 47/460 (10%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP+  +G  G  G  G        P   GPVGPP  +G    +  P        KGE GP
Sbjct: 1126 GPQGPAGRDGLQGPVGL-------PGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGP 1178

Query: 82   PGKPGPRGP---PGPPGFPGKPG-MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPP 137
            PG  GP+GP   PGP G  G+PG  G+ GL GQ G  GP GF   G  GP GL G  GPP
Sbjct: 1179 PGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFP--GPPGPVGLQGLPGPP 1236

Query: 138  GQPGLRGEPGIRGDQGLRGPPGPPGLPG-------PSGITIPGKPGAQGVPGPPGFQGEP 190
            G+ G  G+ G  G  G  GP GP G PG       P GI  PG  G +G PG  G  G P
Sbjct: 1237 GEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP 1296

Query: 191  GPQGEPGPPGDRGLKGDNG----VGQPGLPGAPGQGG---APGPPGLPG-PAGLGKPGLD 242
            G  G PGP G+RG KG++G     G PG  G PG  G   +PGP G PG P   G+PG  
Sbjct: 1297 GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPA 1356

Query: 243  GLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPG 302
            G  G PGDKG+ G PG  G  G  G  GP GPPG  G   PG AG  G QG  GAKGE G
Sbjct: 1357 GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP--PGPAGPEGRQGEKGAKGEAG 1414

Query: 303  TRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL----- 356
              GPPG  GP G  G PG PGP G RG  G  G  G  G PG DG PG  GP GL     
Sbjct: 1415 LEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKG 1474

Query: 357  -GGPPGLPGSAGLPGRRGPPGPKGEAG----PG-----GPPGVPGIRGDQGPSGLAGKPG 406
              GP G  G  GL G  GPPG +GE G    PG     GP G  GI G  GP G  G PG
Sbjct: 1475 DSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG 1534

Query: 407  VPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQ 446
            +PG  G  GA G  GPTGPKGE G  G PG PG  G + Q
Sbjct: 1535 LPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQ 1574



 Score =  287 bits (735), Expect = 2e-77
 Identities = 180/410 (43%), Positives = 204/410 (49%), Gaps = 34/410 (8%)

Query: 181 PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGL-----PGAPGQGGAPGPPGLPGPAG 235
           PG P  Q +   +G  GP G++G KG+  + +PG+     PG  G  G PGPPG  GP G
Sbjct: 432 PGMPANQ-DTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTG 490

Query: 236 -LGKPGLDGLPGAPGDKGESGPPGVPGPR-------GEPGAVGPKGP------PGVDGVG 281
            +G PG  G PG PG  G  G PG PG         G  G  G KGP           + 
Sbjct: 491 QVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAIL 550

Query: 282 VPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRG 340
                 L GP GP G  G PG  GPPG  G  G  G  G  GP+G +GP G  G  G RG
Sbjct: 551 QQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRG 610

Query: 341 EPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG 400
             G DG  G  G  G  G  G  G AGLPG +G  G  G +GP GPPG  G RGD G  G
Sbjct: 611 RAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVG 670

Query: 401 LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
             G PG PG RGL G  GPPGP GP   PG TG  G PG  G +G +G+   PG PG +G
Sbjct: 671 PRGLPGEPGPRGLLGPKGPPGPPGP---PGVTGMDGQPGPKGNVGPQGE---PGPPGQQG 724

Query: 461 PSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGP 520
             G  GL GP G IGP G  G  G+PGLPG PG    G PG  G  GPPG  G  G  GP
Sbjct: 725 NPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGAD--GPPGHPGKEGPPGEKGGQGPPGP 782

Query: 521 PGPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGAVLGKGGKPQFG 565
            GP G PGP G  GA    G+ G     G     G +G +  KG + + G
Sbjct: 783 QGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIG 832


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  447 bits (1150), Expect = e-125
 Identities = 282/649 (43%), Positives = 313/649 (48%), Gaps = 147/649 (22%)

Query: 72  PMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP-------------------------- 105
           P   KG+PGPPG PG  G PG PG PG PG   P                          
Sbjct: 104 PQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSG 163

Query: 106 ----GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPP 161
               GL G PGPAGPPG       GPPG  G  G PG PG +G PG  G  G  GPPGPP
Sbjct: 164 VAVGGLAGYPGPAGPPG-----PPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP 218

Query: 162 GLPGPSGIT-------IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG----V 210
           G  GPSG          PG+PG +G+PGPPG +G  G  G PG  G RG  G NG     
Sbjct: 219 GAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGET 278

Query: 211 GQPGLPGA---PGQGGAPGP------------PGLPGPAGL----------------GKP 239
           G PGL G    PG+ GAPGP            PGLPG AG                 G P
Sbjct: 279 GAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 338

Query: 240 GLDGLPGAPGDKGESGPPGVPG------------PRGEPGAVGPKGPPGVDG-------- 279
           G  G PG+PG KGE GP G PG            P+G  GA GP GPPG++G        
Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEM 398

Query: 280 --VGVPGAAGLPG---PQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPG 334
              G+PGA GL G   P GP+GA G PG RG  G  G  G    G PGP+G+RG AG+PG
Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG--AKGEPGPRGERGEAGIPG 456

Query: 335 LLGDRGEPGEDGEPGEQGPQGL---------------GGPPGLPGSAGLPGRRGPPGPKG 379
           + G +GE G+DG PGE G  GL                GP G+PG  G  G RG PGP G
Sbjct: 457 VPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAG 516

Query: 380 ------EAGPGGPPGVPGIRG---DQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPG 430
                 E G  G PG PG+RG     G  G  GKPG PG +G  G  GPPGP+GP+G+PG
Sbjct: 517 PRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPG 576

Query: 431 FTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGP------------IGPQG 478
             G PG  G  GA G+ G+ G PG PG +GP G  G  GP GP             GP G
Sbjct: 577 VMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPG 636

Query: 479 LPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFD 537
             GL+G PG  GPPGE G+ GEPG  G  G PG PG  G  G PG  GPPG  GAPG   
Sbjct: 637 PQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL-- 694

Query: 538 ETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFP 586
             G AG   P GG +GA    G  P    G       P     L SP P
Sbjct: 695 -RGGAGPPGPEGG-KGAAGPPG--PPGAAGTPGLQGMPGERGGLGSPGP 739



 Score =  438 bits (1127), Expect = e-123
 Identities = 272/608 (44%), Positives = 303/608 (49%), Gaps = 94/608 (15%)

Query: 24  PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPG 83
           P  +   G  G  G AP +  +P   G  G    +G       P P  P    G PG PG
Sbjct: 290 PGENGAPGPMGPRG-APGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPG 348

Query: 84  KPGPRGPPGPPGFPGKPGM-GKPGLHGQ---PGPAGPPGFS-------RMGKAGPPGLPG 132
             G  GP G PG  G PG  G+PG  G     GP GPPG +        MG AG PG PG
Sbjct: 349 AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG 408

Query: 133 KV---GPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG----ITIPGKPGAQ------G 179
            +   GPPG  G  G PG+RG  G  G  G  G PGP G      IPG PGA+      G
Sbjct: 409 LMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDG 468

Query: 180 VPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV----------------GQPGLPGAPGQGG 223
            PG PG  G PG  GE G PG RG  G NG+                G  G  G PG+ G
Sbjct: 469 SPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDG 528

Query: 224 APGPPGLPG-PAGLGKPGLDGLPGAPGDKGES---GPPGVPGPRGEPGAVGPKGPPGVDG 279
            PG PG+ G P   G PG DG PG PG +GES   GPPG  GPRG+PG +G  GP G DG
Sbjct: 529 VPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG 588

Query: 280 V----GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-------------YGMPGLPG 322
                G  G  G PGPQGP G  GE G +GPPG  GP G              G+PG  G
Sbjct: 589 APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG 648

Query: 323 PKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP---KG 379
           P G+ G  G PG  GD G PG  G  G+ G  G  GPPGL G+ GL G  GPPGP   KG
Sbjct: 649 PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708

Query: 380 EAGPGGPP---GVPGIR---------GDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKG 427
            AGP GPP   G PG++         G  GP G  G+PG PG  G+PG  GP GPTGP G
Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 428 EPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG 487
            PG  G+P         G KG+ G PG PG+ GP G PG +G  GP GP G PG  G+ G
Sbjct: 769 PPGPAGQP---------GDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNG 819

Query: 488 LPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPP------GPPGAPGAFDETGI 541
            PG  G+G  G PG  G  GPPGV G PG +GP GPPGP       G PG PGA    G 
Sbjct: 820 EPG--GKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA 877

Query: 542 AGLHLPNG 549
            GL  P G
Sbjct: 878 RGLPGPPG 885



 Score =  433 bits (1113), Expect = e-121
 Identities = 274/619 (44%), Positives = 305/619 (49%), Gaps = 113/619 (18%)

Query: 23   GPRASSG--------GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMD 74
            GP+ + G        GG GG     P    +  + GP GPP   G G       P  P  
Sbjct: 582  GPKGNDGAPGKNGERGGPGGPGPQGPPG--KNGETGPQGPPGPTGPGGDKGDTGPPGPQG 639

Query: 75   LKGEPGP---------PGKPGPRGPPGPPGFPGKPG-MGKPGLHGQPGPAGPPGFSRMGK 124
            L+G PG          PG+PGP+G  G PG PG  G  G PG  G PG AG PG    G 
Sbjct: 640  LQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLR--GG 697

Query: 125  AGPPGLPG---KVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVP 181
            AGPPG  G     GPPG PG  G PG++G  G RG  G PG  G  G   PG PGA GVP
Sbjct: 698  AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE--PGGPGADGVP 755

Query: 182  GPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGL------PGAPGQGGAPGPPGLPGPA 234
            G  G +G  GP G PGP G  G KG+ G  G PG+      PG  G+ G PGP G PG  
Sbjct: 756  GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAP 815

Query: 235  GL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG----------VGVP 283
            G  G+PG  G  GAPG+KGE GPPGV GP G  G  GP GP GV G           G P
Sbjct: 816  GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFP 875

Query: 284  GAAGLPGPQG------PSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRG-------- 328
            GA GLPGP G      P G  G PG  GPPG  G TG  G PG+ GPKGD G        
Sbjct: 876  GARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSP 935

Query: 329  ----------PAGVPGLLGDRGEPGEDGEPGEQG---PQGLGGPPGLPGSAGLPGRRGPP 375
                      P G+ G+ G RG  G  G PG +G   PQG+ G  G PG+ GL G RGPP
Sbjct: 936  GAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPP 995

Query: 376  GPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERG------------LPGAHGPPGPT 423
            GP+G  G  G  G PG  G+ G  GL G+ G PG +G             PG  GPPGP 
Sbjct: 996  GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPV 1055

Query: 424  GPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLK 483
            GP G+ G  G  G  G AGA G  G  G PG  G RG  G  G +G AG  G +G PG  
Sbjct: 1056 GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP 1115

Query: 484  GEPGLPGPPGE-------GRAGEPGTAGPTGPPGVPGS---PGITGPPGP---------- 523
            G PG PGP G+       G AG  G  GP+GPPG  G+   PG  GPPGP          
Sbjct: 1116 GAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSE 1175

Query: 524  --------PGPPGPPGAPG 534
                    PGPPGPPGAPG
Sbjct: 1176 GSPGHPGQPGPPGPPGAPG 1194



 Score =  428 bits (1101), Expect = e-120
 Identities = 270/603 (44%), Positives = 299/603 (49%), Gaps = 61/603 (10%)

Query: 24   PRASSGGGAGGAAGYAPVKYIQPMQKGPVGP---PFREGKGQYLEMPLPLLPMDLKGEPG 80
            P      G  GAAG        P  +GP GP   P  +G       P P  P    GEPG
Sbjct: 470  PGEPGANGLPGAAGERGA----PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525

Query: 81   P---PGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSR-------MGKAGP-- 127
                PG PG RG PG PG PG  G  G PG  G+ G  GPPG S        MG  GP  
Sbjct: 526  RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG 585

Query: 128  ----PGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIP-------GKPG 176
                PG  G+ G PG PG +G PG  G+ G +GPPGP G  G  G T P       G PG
Sbjct: 586  NDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPG 645

Query: 177  AQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV----GQPGLPGAPGQGGAPGPPGLPG 232
              G PG  G  GEPGP+G+ G PG  G KGD G     G PGL GAPG  G  GPPG  G
Sbjct: 646  TGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEG 705

Query: 233  PAGLGKP-------GLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPG 284
              G   P       G  GL G PG++G  G PG  G +GEPG  G  G PG DG  G  G
Sbjct: 706  GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765

Query: 285  AAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGE 344
              G PGP G  G KGE G  G PG+ GP G   PG  G  G  GPAG PG  G  GEPG 
Sbjct: 766  PIGPPGPAGQPGDKGEGGAPGLPGIAGPRG--SPGERGETGPPGPAGFPGAPGQNGEPGG 823

Query: 345  DGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGK 404
             GE G  G +G GGPPG+ G  G  G  GPPGP+G  G  G PG PG  G  G  GL G 
Sbjct: 824  KGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGP 883

Query: 405  PGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI 464
            PG  G  G PG  G PG  GP G  G TG PG PGV+   G KGD G PG+       G 
Sbjct: 884  PGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS---GPKGDAGQPGE------KGS 934

Query: 465  PGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGP 523
            PG QGP G  GP G+ G+ G  GL GPPG  G  G PG  G  G  G PG+ G++G  GP
Sbjct: 935  PGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP 994

Query: 524  PGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTS 583
            PGP G PG  G   E G  G    N G +G + G+ G P  G G+   + +P        
Sbjct: 995  PGPQGLPGLAGTAGEPGRDG----NPGSDG-LPGRDGSPG-GKGDRGENGSPGAPGAPGH 1048

Query: 584  PFP 586
            P P
Sbjct: 1049 PGP 1051



 Score =  422 bits (1084), Expect = e-118
 Identities = 254/542 (46%), Positives = 271/542 (50%), Gaps = 47/542 (8%)

Query: 21   GCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPG 80
            G GP    GG   GAAG             P GPP   G      MP         GE G
Sbjct: 697  GAGPPGPEGGK--GAAG-------------PPGPPGAAGTPGLQGMP---------GERG 732

Query: 81   PPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSRM----GKAGPPGLPGKVG 135
              G PGP+G  G PG PG  G+ GK G  G  GP GPPG +      G+ G PGLPG  G
Sbjct: 733  GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAG 792

Query: 136  PPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGE 195
            P G PG RGE G  G  G  G PG  G PG  G    G PG +G  GPPG  G PG  G 
Sbjct: 793  PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER--GAPGEKGEGGPPGVAGPPGGSGP 850

Query: 196  PGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGL---PGPAG-LGKPGLDGLPGAPGD 250
             GPPG +G+KG+ G  G PG  G PG  G PGPPG    PGP G  G PG DG PG  G+
Sbjct: 851  AGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGN 910

Query: 251  KGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGL 309
             G  G PGV GP+G+ G  G KG PG  G  G PG  G+ G  G  G  G PG  GP G 
Sbjct: 911  TGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGS 970

Query: 310  IGPTGY-------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGL 362
             GP G        G  GL G +G  GP G+PGL G  GEPG DG PG  G  G  G PG 
Sbjct: 971  PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030

Query: 363  PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGP 422
             G  G  G  G PG  G  GP GP G  G  GD+G SG AG  G PG  G  GA GP GP
Sbjct: 1031 KGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090

Query: 423  TGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGL 482
             G KGE G  G  G  G  G  G  G  G PG  G +G  G PG  GP GP+GP G PG 
Sbjct: 1091 RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGK 1150

Query: 483  KGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGP-PGAPGAFDETGI 541
             G  G PGP G    G  G  G  G  G PG PG  GPPGPPG PGP  G  GA    GI
Sbjct: 1151 DGTSGHPGPIGP--PGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGI 1208

Query: 542  AG 543
             G
Sbjct: 1209 GG 1210



 Score =  419 bits (1077), Expect = e-117
 Identities = 272/645 (42%), Positives = 303/645 (46%), Gaps = 132/645 (20%)

Query: 24   PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPG 83
            P +  G G+ G  G  P    +  + GP GP    G+   +  P P      KG  G PG
Sbjct: 539  PGSPGGPGSDGKPG-PPGSQGESGRPGPPGPSGPRGQPGVMGFPGP------KGNDGAPG 591

Query: 84   K------PGPRGPPGPPGFPGKPG-------------------MGKPGLHGQPGPAGPPG 118
            K      PG  GP GPPG  G+ G                    G  GL G PG  GPPG
Sbjct: 592  KNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG 651

Query: 119  FS-------RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLR---------------G 156
             +         G AG PG PG  G  G PG RG PG+ G  GLR               G
Sbjct: 652  ENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAG 711

Query: 157  PPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQP- 213
            PPGPPG  G  G+  +PG+ G  G PGP G +GEPG  G  G PG  G +G  G +G P 
Sbjct: 712  PPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPG 771

Query: 214  --GLPGAPGQGGAPGPPGL---------------PGPAGL-------GKPGLDGLPGAPG 249
              G PG  G+GGAPG PG+               PGPAG        G+PG  G  GAPG
Sbjct: 772  PAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPG 831

Query: 250  DKGESGPPGVPGPRGEPGAVGPKGPPGVDG----------VGVPGAAGLPGP------QG 293
            +KGE GPPGV GP G  G  GP GP GV G           G PGA GLPGP       G
Sbjct: 832  EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPG 891

Query: 294  PSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGD------------RGPAGVPGLLGD-- 338
            P G  G PG  GPPG  G TG  G PG+ GPKGD            +GP G PG LG   
Sbjct: 892  PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAG 951

Query: 339  -------RGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPG 391
                    G PG  G  G  GPQG+ G  G PG+ GL G RGPPGP+G  G  G  G PG
Sbjct: 952  ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011

Query: 392  IRGDQGPSGLAGKPGVPGER------------GLPGAHGPPGPTGPKGEPGFTGRPGGPG 439
              G+ G  GL G+ G PG +            G PG  GPPGP GP G+ G  G  G  G
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG 1071

Query: 440  VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAG 498
             AGA G  G  G PG  G RG  G  G +G AG  G +G PG  G PG PGP G +G  G
Sbjct: 1072 PAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131

Query: 499  EPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAG 543
             PG AGP GP G  G PG  G  G PGP GPPG  G   E G  G
Sbjct: 1132 SPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG 1176



 Score =  409 bits (1050), Expect = e-114
 Identities = 242/526 (46%), Positives = 272/526 (51%), Gaps = 72/526 (13%)

Query: 91  PGPPGFPGKP--GMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGL------ 142
           P PP  P +P  G G  G  G PGP G PG  R G  G PG PG  G PG PG+      
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKGDPGPPGIPG--RNGDPGIPGQPGSPGSPGPPGICESCPT 146

Query: 143 -----------------RGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPG 185
                                G+ G  G  GPPGPPG PG SG   PG PG+ G  GPPG
Sbjct: 147 GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG--HPGSPGSPGYQGPPG 204

Query: 186 FQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAGL-GKPGLD- 242
             G+ GP G PGPPG  G  G  G  G+ G PG PG+ G PGPPG+ GPAG+ G PG+  
Sbjct: 205 EPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKG 264

Query: 243 --GLPGAPGDKGESGPP------GVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGLPGPQG 293
             G  G  G+KGE+G P      G+PG  G PG +GP+G PG  G  G+PGAAG  G  G
Sbjct: 265 HRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG 324

Query: 294 PSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGP 353
             G+ G+PG  GPPG       G PG PG KG+ GPAG P   G  G PG+ GEPG QG 
Sbjct: 325 ARGSDGQPGPPGPPGTA-----GFPGSPGAKGEVGPAGSP---GSNGAPGQRGEPGPQGH 376

Query: 354 QGLGGPPGLPGSAGLPGRRGPPGP------------KGEAGPGGPPGVPGIRGDQGPSGL 401
            G  GPPG PG  G PG +G  GP            +G  GP G  G PG+RG  G  G 
Sbjct: 377 AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK 436

Query: 402 AGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGP 461
            G  G PG RG  G  G PG  G KGE G  G PG PG  G  G  G+ G PG  G  GP
Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496

Query: 462 SGIPGLQGPA------GPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGS 514
           +GIPG +GPA      GP GP+G  G  G  G+PG PG  G  G PG  G  G PG PGS
Sbjct: 497 NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556

Query: 515 PGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGG 560
            G +G PGPPGP GP G PG     G  G    N G  G    +GG
Sbjct: 557 QGESGRPGPPGPSGPRGQPGVMGFPGPKG----NDGAPGKNGERGG 598



 Score =  382 bits (981), Expect = e-106
 Identities = 227/500 (45%), Positives = 253/500 (50%), Gaps = 71/500 (14%)

Query: 126 GPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGL-----PGP-------------S 167
           GP G  G  GPPG PG  G+PGI G  G  G PGPPG+      GP             S
Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162

Query: 168 GITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGP 227
           G+ + G  G  G  GPPG  G PG  G PG PG  G +G      PG PG  G  G PGP
Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGP-----PGEPGQAGPSGPPGP 217

Query: 228 PGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG----VGV 282
           PG  GP+G  GK G  G PG PG++G  GPPG+ GP G PG  G KG  G DG     G 
Sbjct: 218 PGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGE 277

Query: 283 PGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGE 341
            GA GL G  G  G  G PG  GP G  G  G  G+PG  G +G+ G  G  G  G  G 
Sbjct: 278 TGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGP 337

Query: 342 PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGL 401
           PG  G PG  G +G  GP G PGS G PG+RG PGP+G AG  GPPG PGI G  G  G 
Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGE 397

Query: 402 AGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGA------LGQKGDLGLPGQ 455
            G  G+PG  GL GA GPPGP G  G PG  G  G PG  GA       G++G+ G+PG 
Sbjct: 398 MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGV 457

Query: 456 PGLRGPS---------------------GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG- 493
           PG +G                       G PG +GPAGP G  G  G  GE G PGP G 
Sbjct: 458 PGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGP 517

Query: 494 EGRAGEPGTAG-PTGP-----PGVPGSPGITGPPGPPGP------PGPPGAPGAFDETGI 541
            G AGEPG  G P GP     PG PG PG  G PGPPG       PGPPG  G   + G+
Sbjct: 518 RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGV 577

Query: 542 AGLHLPNGGVEGAVLGKGGK 561
            G   P G  +GA  GK G+
Sbjct: 578 MGFPGPKGN-DGAP-GKNGE 595



 Score =  201 bits (510), Expect = 3e-51
 Identities = 141/379 (37%), Positives = 163/379 (43%), Gaps = 120/379 (31%)

Query: 291 PQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGE 350
           PQ P+     P  +GP G              PKGD GP G+PG  GD G PG+      
Sbjct: 89  PQPPTAPTRPPNGQGPQG--------------PKGDPGPPGIPGRNGDPGIPGQ------ 128

Query: 351 QGPQGLGGPPGLPGS-----------------------------------AGLPGRRGPP 375
                    PG PGS                                   AG PG  GPP
Sbjct: 129 ---------PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPP 179

Query: 376 GP------------------------KGEAGPGGPPGVPGIRGDQGPSGL---AGKPGVP 408
           GP                         G+AGP GPPG PG  G  GP+G    +G+PG P
Sbjct: 180 GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP 239

Query: 409 GERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQ 468
           GERGLP   GPPG  GP G PGF G  G  G  G  G+KG+    G PGL+G +G+PG  
Sbjct: 240 GERGLP---GPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGE---TGAPGLKGENGLPGEN 293

Query: 469 GPAGPIGPQGLPGLKGEPGLPGPPG-------EGRAGEPGTAGPTGPPGVPGSPGITGPP 521
           G  GP+GP+G PG +G PGLPG  G        G  G+PG  GP G  G PGSPG  G  
Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353

Query: 522 GPPGPPGPPGAPGAFDE---TGIAGLHLPNG--GVEGAVLGKGGKPQFGL----GELSAH 572
           GP G PG  GAPG   E    G AG   P G  G+ G+  GKG     G+    G + A 
Sbjct: 354 GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413

Query: 573 ATPAFTAVLTSPFPASGMP 591
             P        P  A+G P
Sbjct: 414 GPP-------GPAGANGAP 425



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 20/46 (43%), Positives = 21/46 (45%)

Query: 498 GEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAG 543
           GE     P  P      P   GP GP G PGPPG PG   + GI G
Sbjct: 82  GECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPG 127


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  447 bits (1149), Expect = e-125
 Identities = 267/604 (44%), Positives = 312/604 (51%), Gaps = 102/604 (16%)

Query: 48  QKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG----MG 103
           +KG  G P    KGQ  E P         G PGP G  GP GPPGPPGFPG PG     G
Sbjct: 374 EKGAKGEPAVIEKGQQFEGP--------PGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAG 425

Query: 104 KPGLHGQPGPAGPPGF-------------------------------SRMGKAGPPGLPG 132
            PG+ G  G  GPPG                                +++   GPPG  G
Sbjct: 426 LPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVG 485

Query: 133 KVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG-------ITIPGKPGAQGVPGPPG 185
             G PG  GL G PG++G++G  GP GP GL GP G       +  PG  GA+G+PG  G
Sbjct: 486 LTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTG 545

Query: 186 FQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPP------GLPGPAGL-- 236
            +G+ G  G PG PG++G +GD G VGQPG PG  G+ GA GPP      G PGP GL  
Sbjct: 546 PKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG 605

Query: 237 --------GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-------- 280
                   G+PG+ G+ GAPG KG  GPPG PGP G+ G  G +G PG  G+        
Sbjct: 606 PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKG 665

Query: 281 --GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLG 337
             G PG  GLPG  GP G  G  G  G  G  GP G  G PG PGP+G +G +G  GL G
Sbjct: 666 PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQG 725

Query: 338 DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
           ++GE GEDG PG +G  GL G  G PG+ G  G  GP GPKG+AG  G  G PG  G++G
Sbjct: 726 EKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKG 785

Query: 398 PSGLAGKPGVPGERGLPGAHGPPGPTGPKGE------------------PGFTGRPGGPG 439
             G+ G PG PG  G  G+ G PGP GP GE                  PG  G  G PG
Sbjct: 786 KLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPG 845

Query: 440 VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAG 498
             G  G KGD+G  G PG+ G  G+PGLQGP G  GP+G PG +G+ G PG PG+ G  G
Sbjct: 846 ATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELG 905

Query: 499 EPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGK 558
             G  GP GP GV G  G TG  GP G  GPPG PG   E G+ GL     G EGA  G+
Sbjct: 906 FQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLE----GREGA-KGE 960

Query: 559 GGKP 562
            G P
Sbjct: 961 LGPP 964



 Score =  425 bits (1093), Expect = e-119
 Identities = 265/579 (45%), Positives = 303/579 (52%), Gaps = 53/579 (9%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP+  +G  G  G  G A  K    +   P G P R G    +  P PL P+  KG+ G 
Sbjct: 764  GPKGQAGQAGEEGPPGSAGEKGKLGVPGLP-GYPGRPGPKGSIGFPGPLGPIGEKGKSGK 822

Query: 82   PGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRM-GKAGPPGLPGKVGPPGQP 140
             G+PG  G  GPPG  G+   G+PG  GQPGP G  G     G  G  GLPG  GPPG P
Sbjct: 823  TGQPGLEGERGPPGSRGE--RGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFP 880

Query: 141  GLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPG 200
            G +G PG +G  G  G PG  G  G  G T  G PG  GV GP G  GE GP GE GPPG
Sbjct: 881  GPKGPPGHQGKDGRPGHPGQRGELGFQGQT--GPPGPAGVLGPQGKTGEVGPLGERGPPG 938

Query: 201  DRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAGL-GKPGLDGLPGAPGD---KGESG 255
              G  G+ G+ G  G  GA G+ G PGP G  GPAGL G PG  G PG PG    KG+ G
Sbjct: 939  PPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKG 998

Query: 256  PPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY 315
            PPG  G  G PG  GP GP G  G+G+PG +G  GP GP+G KG  G RGPPG   PTG 
Sbjct: 999  PPGPVGANGSPGERGPLGPAG--GIGLPGQSGSEGPVGPAGKKGSRGERGPPG---PTGK 1053

Query: 316  -GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGP 374
             G+PG  GP G  G AG  G  GD+G+ G  G  G +G +G  GPPG PG  G  G  GP
Sbjct: 1054 DGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGP 1113

Query: 375  PGPKGEAGPGGPPGVPGIRGDQG---------PSGLAGKPGVPGERG------------L 413
            PG  G  G  GPPG+ G +GD G         P GL G PG PGE+G             
Sbjct: 1114 PGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGA 1173

Query: 414  PGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLG---LPGQPGLRGPSGIPGLQGP 470
            PG  GP GPTG +G PG  G  G PG  G  G++GD G    PG PG+ GP G  G +G 
Sbjct: 1174 PGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGD 1233

Query: 471  AGPIGPQGLPGLKGEPGLPGPPGE----------GRAGEPGTAGPTGPPGVPGSPGITGP 520
            +GP G  G PG KG PG  G  G           G  G+PG +G  G PG  G PG  G 
Sbjct: 1234 SGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGG 1293

Query: 521  PGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKG 559
            PGPPG  G PGAPG   + G +G H+   G EG    KG
Sbjct: 1294 PGPPGASGEPGAPGPPGKRGPSG-HMGREGREGEKGAKG 1331



 Score =  422 bits (1084), Expect = e-118
 Identities = 279/647 (43%), Positives = 314/647 (48%), Gaps = 144/647 (22%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQ--PMQKGPVGPPFREGK-------GQYLEM------ 66
            GP+   G  GA G  G   +  +Q  P   GP GPP  +GK       GQ  E+      
Sbjct: 851  GPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQT 910

Query: 67   --PLP---LLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM----------GKPGLHGQP 111
              P P   L P    GE GP G+ GP GPPGPPG  G PG+          G PG  G+ 
Sbjct: 911  GPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKE 970

Query: 112  GPAGPPGF----SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRG------------DQGLR 155
            GPAG  GF       G  GP GL G  GPPG  G  G PG RG              G  
Sbjct: 971  GPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSE 1030

Query: 156  GPPGPPGL---------PGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLK 205
            GP GP G          PGP+G   IPG  G  G PG  G  GE G +G+ G PG +G K
Sbjct: 1031 GPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSK 1090

Query: 206  GDNG-VGQPGLPGAPGQGGAPGPPGLPGPAG----------------------LGKPGLD 242
            GD G  G PG PG  G  G PGPPG  G  G                      +G PGL 
Sbjct: 1091 GDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQ 1150

Query: 243  GLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEP 301
            GLPG PG+KGE G  G  GP G PG  GP+GP G +G  G+PG  G PG  G  G +G+ 
Sbjct: 1151 GLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDA 1210

Query: 302  GTRGPPGLIGPTGYGMPGLPGPKGD------RGPAGVPGLLGDRGEPGEDGEPGEQGPQG 355
            G  GPPG         PG+PGPKGD       GP+G  G  G +G PGEDG  G  GP G
Sbjct: 1211 GDPGPPGA--------PGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTG 1262

Query: 356  LGG---PPGLPGSAGL---------PGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAG 403
            L G   PPG PG +G+         PG  G PGP G +G  G PG PG RG  G  G  G
Sbjct: 1263 LPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREG 1322

Query: 404  KPGVPGERGLPGAHGPPGPTGP---KGEPGFTGRPGGPGVAGALGQKGDLGLPGQ---PG 457
            + G  G +G PG  GPPG TGP   +G PG  G  G  G+ G +G+ G LG PGQ   PG
Sbjct: 1323 REGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPG 1382

Query: 458  LRGPSGIPGLQGPAGP------------IGP---------QGLPGLKGEPGL---PGPPG 493
              GPSG+PGL+G  GP            IGP         QGLPG++G PG    PGPPG
Sbjct: 1383 PLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442

Query: 494  E----GRAGEPGTAGPTGPPGVPGSPGITGP---PGPPGPPGPPGAP 533
                 G  G PG AGP G  G  GSPG  GP    GP GPPGPPGAP
Sbjct: 1443 PIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489



 Score =  416 bits (1068), Expect = e-116
 Identities = 265/584 (45%), Positives = 303/584 (51%), Gaps = 66/584 (11%)

Query: 35   AAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPP 94
            A   A ++  Q   KGP GP    G+     + LP  P  LKGE G  G  GPRG  GP 
Sbjct: 464  AQAQAVLQQTQLSMKGPPGPVGLTGRPG--PVGLPGHP-GLKGEEGAEGPQGPRGLQGPH 520

Query: 95   GFPGKPG-MGKPGLHGQ---PGPAGPPGFSRMGKAGPPGLPGKVGPPG------QPGLRG 144
            G PG+ G MG+PG  G    PG  GP G    G  G PGLPG+ G  G      QPG  G
Sbjct: 521  GPPGRVGKMGRPGADGARGLPGDTGPKG--DRGFDGLPGLPGEKGQRGDFGHVGQPGPPG 578

Query: 145  EPGIRGDQGLRGPPGPPGLPGPSGITIP-------GKPGAQGVPGPPGFQGEPGPQGEPG 197
            E G RG +G  GP G  G PGP G+  P       G+PG  G+ G PG +G  GP GEPG
Sbjct: 579  EDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPG 638

Query: 198  PPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAG----LGKPGLDGLPG---APG 249
            PPG +G  G  G+ G  GL G PG+ G PG PG+PG  G    LG PG +G  G   A G
Sbjct: 639  PPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQG 698

Query: 250  DKGESGPPGVPGPRGEPGAVG------PKGPPGVDGV----------------GVPGAAG 287
              G +GPPG PGPRG  G  G       KG  G DG                 G PG  G
Sbjct: 699  PPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRG 758

Query: 288  LPGPQGPSGAKGEPGTRGPPGLIGPTGY----GMPGLPGPKGDRGPAGVPGLLGDRGEPG 343
              GP+GP G  G+ G  GPPG  G  G     G+PG PG  G +G  G PG LG  GE G
Sbjct: 759  EDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG 818

Query: 344  EDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAG 403
            + G+ G+ G +G  GPPG  G  G PG  G PGPKG+ G  G PG+P   G++G  GL G
Sbjct: 819  KSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIP---GEKGLPGLQG 875

Query: 404  KPGVPGERGLPGAHGP---PGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
             PG PG +G PG  G    PG  G +GE GF G+ G PG AG LG +G  G  G  G RG
Sbjct: 876  PPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERG 935

Query: 461  PSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITG 519
            P G PG  G  G  G +G  G KGE G PGP G EG AG  G  GP G PG PG  G+ G
Sbjct: 936  PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKG 995

Query: 520  PPGPPGPPGPPGAPGAFDETGIA-GLHLP-NGGVEGAVLGKGGK 561
              GPPGP G  G+PG     G A G+ LP   G EG V G  GK
Sbjct: 996  DKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPV-GPAGK 1038



 Score =  404 bits (1037), Expect = e-112
 Identities = 270/674 (40%), Positives = 323/674 (47%), Gaps = 143/674 (21%)

Query: 23   GPRASSGG-------GAGGAAGYAPVKYIQPMQKGPVGPPFREG-------------KGQ 62
            GP+ S G        G  G +G    K  QP  +G  GPP   G             KG 
Sbjct: 800  GPKGSIGFPGPLGPIGEKGKSG----KTGQPGLEGERGPPGSRGERGQPGATGQPGPKGD 855

Query: 63   YLEMPLPLLPMD--LKGEPGPPGKPGPRGPPGPPGFPGKPG----MGKPGLHGQPGPAGP 116
              +   P +P +  L G  GPPG PGP+GPPG  G  G+PG     G+ G  GQ GP GP
Sbjct: 856  VGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGP 915

Query: 117  PGF----SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRG---PPGPPGLPGPSGI 169
             G      + G+ GP G  G  GPPG PG +G PG+ G +G +G   PPGP G  GP+G+
Sbjct: 916  AGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGL 975

Query: 170  T-IPGKPGAQGVPGPPGFQGE---PGPQGEPGPPGDRG---------LKGDNG----VGQ 212
               PG  G  G PGP G +G+   PGP G  G PG+RG         L G +G    VG 
Sbjct: 976  RGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGP 1035

Query: 213  PGLPGAPGQGGAPGPPG---LPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGA 268
             G  G+ G+ G PGP G   +PGP G LG PG  G  G  GDKG+ G PG  G +G+ G 
Sbjct: 1036 AGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGD 1095

Query: 269  VGPKGPPGVDGV-------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPG- 319
             GP G PG+ G        G  GA G  GP G  G KG+ G RG  G+IGP G  G+PG 
Sbjct: 1096 AGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGP 1155

Query: 320  -----------------LPGPKGDRGPAG---VPGLLGDRGEPGEDGEPGEQGPQGLGGP 359
                              PGP+G +GP G    PGL G  G+PG  GE GE+G  G  GP
Sbjct: 1156 PGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGP 1215

Query: 360  PGLPG------------------SAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGL 401
            PG PG                  +AG PG++GPPG  G  G  GP G+PG  G  G  G+
Sbjct: 1216 PGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGV 1275

Query: 402  AGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGP 461
            +G  G PGE+G PG  G PGP G  GEPG  G PG  G +G +G++G  G  G  G  GP
Sbjct: 1276 SGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGP 1335

Query: 462  SGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-------GRAGEPGTAGPTGPPGVPGS 514
             G PG  GP G  GP G  G +G  G+PGP GE       G+ G PG  GP+G PG+ G 
Sbjct: 1336 DGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGD 1395

Query: 515  PG------------ITGPP---------------GPPGPPGPPGAPGAFDETGIAGLHLP 547
             G            + GPP               GPPGP G PG PG     G    H  
Sbjct: 1396 TGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLG----HPG 1451

Query: 548  NGGVEGAVLGKGGK 561
              GV G +  KG K
Sbjct: 1452 PPGVAGPLGQKGSK 1465



 Score =  366 bits (940), Expect = e-101
 Identities = 233/515 (45%), Positives = 261/515 (50%), Gaps = 79/515 (15%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREG-KGQYLEMPLPLLPMDLKGEPG 80
            GP   +GG G  G +G           +GPVGP  ++G +G+             +G PG
Sbjct: 1013 GPLGPAGGIGLPGQSG----------SEGPVGPAGKKGSRGE-------------RGPPG 1049

Query: 81   PPGK---PGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGP 136
            P GK   PGP GP GPPG  G  G  G  G  G PG  G  G    G AGPPG PG  GP
Sbjct: 1050 PTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDK--GDAGPPGQPGIRGP 1107

Query: 137  PGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGP 192
             G PG    PG  G QG RGPPG  G  G  G+     + G PG QG+PGPPG +GE G 
Sbjct: 1108 AGHPG---PPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164

Query: 193  QGEPGP---PGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAP 248
             G  GP   PG RG +G  G  G PGLPG  GQ GA G  G  G AG   PG  G PG P
Sbjct: 1165 VGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAG--DPGPPGAPGIP 1222

Query: 249  GDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-------GVPGAAGLPGPQGPSGAKGEP 301
            G KG+ G  G  GP G  G  G KGPPG DG        G+PG  G PG  G SG  G P
Sbjct: 1223 GPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSP 1282

Query: 302  GTRGPPGLIG----PTGYGMPGLPGPKGDRGPAGVPGL------LGDRGEPGEDGEPGEQ 351
            G +G PG +G    P   G PG PGP G RGP+G  G        G +GEPG DG PG  
Sbjct: 1283 GEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRT 1342

Query: 352  GPQGLGGPPG---------LPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA 402
            GP G  GPPG         +PG  G PG  G PG  G  GP GP G+PG++GD GP G  
Sbjct: 1343 GPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKG-- 1400

Query: 403  GKPGVPGERGLPGAHGPPGPTGPKGE---PGFTGRPGGPGVAGALGQKGDLGLPGQPGLR 459
                  G  GL G  GPPG  G KG+   PG  G PG  G  G  G  G LG PG PG+ 
Sbjct: 1401 ----EKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVA 1456

Query: 460  GPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE 494
            GP G  G +G  G +GP+G  G  G PG PG P E
Sbjct: 1457 GPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAE 1491



 Score =  326 bits (835), Expect = 5e-89
 Identities = 205/459 (44%), Positives = 227/459 (49%), Gaps = 78/459 (16%)

Query: 31   GAGGAAGYAPVKYIQPMQKGPVGPPFREG-KGQYLEMPLPLLPMDLKGEPGPPGKPGPRG 89
            GA G +G       +   KG VG P  +G KG              KG+ GPPG+PG RG
Sbjct: 1067 GAAGPSG-------EEGDKGDVGAPGHKGSKGD-------------KGDAGPPGQPGIRG 1106

Query: 90   PPGPPGFPGKPGM----GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGE 145
            P G PG PG  G     G PGL GQ G  G  GF  +G  GPPGL G  GPPG+ G  G+
Sbjct: 1107 PAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGF--VGVIGPPGLQGLPGPPGEKGEVGD 1164

Query: 146  PGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPG----- 200
             G  G  G  GP GP G  G  G   PG PG  G PG  G +GE G  G+PGPPG     
Sbjct: 1165 VGSMGPHGAPGPRGPQGPTGSEGT--PGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIP 1222

Query: 201  ----DRGLKGDNG----VGQPGLPGAPGQGGAPG---PPGLPG----PAGLGKPGLDGLP 245
                D G KGD+G     G PG  G PG+ GA G   P GLPG    P   G  G+DG P
Sbjct: 1223 GPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSP 1282

Query: 246  GAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-------VGVPGAAGLPGPQGPSGAK 298
            G  GD G+ G PG PG  GEPGA GP G  G  G        G  GA G PGP GP G  
Sbjct: 1283 GEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRT 1342

Query: 299  GEPGTRGPPGLIGPTGY-------------GMPGLPGPKGDRGPAGVPGLLGDRGEPGED 345
            G  G RGPPG +GP G              G PG  GP G  GP+G+PGL GD G  GE 
Sbjct: 1343 GPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEK 1402

Query: 346  GEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKP 405
            G  G  G  G  G  G  G  GLPG +GPPGPKG+ GP GP G           G  G P
Sbjct: 1403 GHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIG---------SLGHPGPP 1453

Query: 406  GVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGAL 444
            GV G  G  G+ G PG  GP+G+ G  G PG PG    L
Sbjct: 1454 GVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAEL 1492



 Score =  213 bits (542), Expect = 5e-55
 Identities = 148/379 (39%), Positives = 163/379 (43%), Gaps = 109/379 (28%)

Query: 293 GPSGAKGEPGT-------RGPPGLIGPTGY----------GMPGLPGPKGDRGPAGVPGL 335
           G  GAKGEP          GPPG  GP G           G PG PGP G  G  G+PG+
Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGI 432

Query: 336 LGDRGEPGE------------------------------------DGEPGEQGPQGLGGP 359
            G RG PG                                      G PG  G  G  GP
Sbjct: 433 DGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGP 492

Query: 360 PGLPGSAGLPGR---RGPPGPKGEAGPGGP------------------------------ 386
            GLPG  GL G     GP GP+G  GP GP                              
Sbjct: 493 VGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGF 552

Query: 387 ---PGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPT------------GPKGEPGF 431
              PG+PG +G +G  G  G+PG PGE G  GA GPPGPT            GP+G PG 
Sbjct: 553 DGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGP 612

Query: 432 TGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGP 491
           TGRPG  G+ GA G KG++G PG+PG  G  G  G QG  GP G  G PG KG PG PG 
Sbjct: 613 TGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGI 672

Query: 492 PG----EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLP 547
           PG    +G  G PG  GPTG  G  G PG  GPPG PGP G  G  G     G  G    
Sbjct: 673 PGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGE 732

Query: 548 NG--GVEGAVLGKG--GKP 562
           +G  G +G V  KG  GKP
Sbjct: 733 DGFPGFKGDVGLKGDQGKP 751



 Score =  116 bits (291), Expect = 6e-26
 Identities = 91/262 (34%), Positives = 102/262 (38%), Gaps = 83/262 (31%)

Query: 363 PGSAGLPGRRGPPG--PKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP 420
           PG AG  G +G P    KG+   G PPG PG +G  GPSG  G PG PG+          
Sbjct: 370 PG-AGEKGAKGEPAVIEKGQQFEG-PPGAPGPQGVVGPSGPPGPPGFPGD---------- 417

Query: 421 GPTGPKGEPGFTGRP--------------------------------------------- 435
              GP G  G  G P                                             
Sbjct: 418 --PGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQL 475

Query: 436 ---GGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP 492
              G PG  G  G+ G +GLPG PGL+G  G  G QGP G  GP G PG  G+ G PG  
Sbjct: 476 SMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPG-- 533

Query: 493 GEGRAGEPGTAGPTGPPGVPGSPGI------------TGPPGPPGPPGPPGAPGAFDETG 540
            +G  G PG  GP G  G  G PG+             G PGPPG  G  GA G    TG
Sbjct: 534 ADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTG 593

Query: 541 IAGLHLPNGGVEGAVLGKGGKP 562
            AG   P G     +LG  G P
Sbjct: 594 QAGEPGPRG-----LLGPRGSP 610


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  441 bits (1135), Expect = e-124
 Identities = 274/630 (43%), Positives = 316/630 (50%), Gaps = 65/630 (10%)

Query: 23   GPRASSGG----GAGGAAGYAPVKYI--QPMQKGPVGPPFREGKGQYLEMPLP---LLPM 73
            GP+   G     GA G AG    +    +P   GP+GPP   G       P       P 
Sbjct: 468  GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 527

Query: 74   DLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSRMGKAGPPGLPG 132
               GE GP G  GP+G  G PG PG+PG+ G  GL G+PG AGP G  ++G +G PG  G
Sbjct: 528  GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG--KVGPSGAPGEDG 585

Query: 133  KVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGP 192
            + GPPG  G RG+PG+ G  G +G  G PG  G  G+  PG PG +G+PG  G  G  GP
Sbjct: 586  RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL--PGAPGLRGLPGKDGETGAAGP 643

Query: 193  QGEPGPPGDRGLKGDNGV----GQPGLPGAPGQGGAPGPPGLPGPAGL----------GK 238
             G  GP G+RG +G  G     G PG PG PG+GG PG  G+PG AG           G 
Sbjct: 644  PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703

Query: 239  PGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV----GVPG---AAGLPGP 291
            PG  G PGA G +G  G PG PG  G  GA GP GPPG  G     G+PG   AAG+ GP
Sbjct: 704  PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 763

Query: 292  QGPSGAKGEPGTRGPPG------LIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGE 344
            +G  G  GE G  G PG      L GP G  G  G  G KG+ GP G  G  G RG PGE
Sbjct: 764  KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 823

Query: 345  DGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGK 404
             GE G  GP G  GPPG  G  G  G +G  G KG+AG  GP G  G  G QGP+G+ G 
Sbjct: 824  RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 883

Query: 405  PGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI 464
             G  G +G PGA G PG  G  G PG  G PG PG  G  G+ G  G  G  G  G +G 
Sbjct: 884  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943

Query: 465  PGLQGPAGPIGPQGLPGLKGEPGLPGPPG----------------EGRAGEPGTAGPTGP 508
            PGLQGPAGP G +G PG  G  G  GPPG                 G  G PG  GP+G 
Sbjct: 944  PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 1003

Query: 509  PGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKPQFGL 566
            PG  G+PG +G  GPPGP GPPG  G   E G  G    +G  G +GA   KG +     
Sbjct: 1004 PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR----- 1058

Query: 567  GELSAHATPAFTAVLTSPFPASGMPVKFDR 596
            GE  A   P       SP PA     + DR
Sbjct: 1059 GETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088



 Score =  429 bits (1103), Expect = e-120
 Identities = 259/561 (46%), Positives = 283/561 (50%), Gaps = 51/561 (9%)

Query: 50  GPVGPPFREG----KGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG---- 101
           GP GP   +G    +G   E   P  P    GEPG PG PGP GPPGPPG PG  G    
Sbjct: 123 GPQGPAGEQGPRGDRGDKGEKGAPG-PRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAA 181

Query: 102 ---------MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQ 152
                     G   L    GP GP G    G  GP G PG  G  G PG  GEPG+ G  
Sbjct: 182 QMAGGFDEKAGGAQLGVMQGPMGPMG--PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM 239

Query: 153 GLRGPPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKG-DNGV 210
           G RGPPGPPG PG  G    PGK G +G PGP G +G PG  G PG  G RG  G D   
Sbjct: 240 GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAK 299

Query: 211 GQPGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAV 269
           G+ G PG  G+ G+PG  G PGP G  G PG  G  G  G  G  G  G PGP G PG V
Sbjct: 300 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 359

Query: 270 GPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDR 327
           GP G PG  G  G  G AG  G +GP GA+G  G  G PG  GP G  G PG  G  G +
Sbjct: 360 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 419

Query: 328 GPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPP 387
           G AG PG+ G  G PG  G PG QG  G  GP G  G  G+ G +G  GPKGE GP GP 
Sbjct: 420 GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 479

Query: 388 GVPGIRGDQGPSGLAGKPG------VPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVA 441
           G PG  G++G  G  G+PG       PGERG PG  G PG  G  G  G  G  G  G+A
Sbjct: 480 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 539

Query: 442 GALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAGEP 500
           G  G  GD G PG+PGL G  G+ G  G AGP G  G  G  GE G PGPPG +G  G+P
Sbjct: 540 GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQP 599

Query: 501 GTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGA- 554
           G  G  GP G  G PG  G  G PG PG  G PG   ETG AG   P G     G +GA 
Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659

Query: 555 -------------VLGKGGKP 562
                          G+GGKP
Sbjct: 660 GPSGFQGLPGPPGPPGEGGKP 680



 Score =  427 bits (1097), Expect = e-119
 Identities = 278/625 (44%), Positives = 314/625 (50%), Gaps = 118/625 (18%)

Query: 31   GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 90
            GA G  G A  K + P   G  G P ++G+      P P  P   +GE G PG  G +G 
Sbjct: 609  GANGEPGKAGEKGL-PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 667

Query: 91   PGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGE----- 145
            PGPPG PG+ G  KPG  G PG AG PG   +G  G  G PG+ G PG  GL+G      
Sbjct: 668  PGPPGPPGEGG--KPGDQGVPGEAGAPGL--VGPRGERGFPGERGSPGAQGLQGPRGLPG 723

Query: 146  -PGIRGDQGLRGPPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQG---EPGPQGEPG--- 197
             PG  G +G  GP GPPG  GP G+  +PG+ GA G+ GP G +G   E GP+G PG   
Sbjct: 724  TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 783

Query: 198  ---------PPGDRGLKGDNG-VGQPGLPGAPGQGGAPGP---PGLPGPAGL-GKPGLDG 243
                     PPG  G  G+ G VG PG  G+ G  GAPG     G PGPAG  G PG DG
Sbjct: 784  GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADG 843

Query: 244  LPGAPGDKGESGPPG---VPGPRGEPGAVGPKGPPGVDGV-------GVPGAAGLPGPQG 293
             PGA G++GE+G  G    PGP+G  GA GP+GP GV G        G PGA G PG  G
Sbjct: 844  QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG 903

Query: 294  PSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGP---AGVPGLLGDRGEPGEDGEPGE 350
              G  G  G  GPPG  GP+G   P   G +GD GP   AG PGL G  G PGE GEPG+
Sbjct: 904  RVGPPGSNGNPGPPGPPGPSGKDGP--KGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 961

Query: 351  QGPQGLGGPPGLPGSAG------LPGRRGP------PGPKGEAGPGGPPGVPGIRGDQGP 398
             GP G  GPPG  G AG      LPG+RG       PGP GE G  G PG  G RG  GP
Sbjct: 962  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021

Query: 399  ---SGLAGKPGVPGERGLPGAHGPPG------------PTGPKGEPGFTGRPGGPGVAGA 443
                GL G  G PG  G PGA GPPG             TG  G PG  G PG PG AG 
Sbjct: 1022 VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081

Query: 444  LGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG---------------L 488
             G++GD G  G  G  GPSG  G +G  GP GP+G  G  GEPG               L
Sbjct: 1082 TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGL 1141

Query: 489  PGPPG----EGRAGEPGTAGPTGPPG---------VPGSPGITGPPGP------------ 523
            PGPPG    +G +G  G +GP GPPG           G PG  GPPGP            
Sbjct: 1142 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201

Query: 524  ---PGPPGPPGAPG-AFDETGIAGL 544
               PGPPGPPG PG   D +  AGL
Sbjct: 1202 PGNPGPPGPPGPPGPGIDMSAFAGL 1226



 Score =  413 bits (1061), Expect = e-115
 Identities = 265/620 (42%), Positives = 294/620 (47%), Gaps = 94/620 (15%)

Query: 23  GPRASSG-GGAGGAAGYA--PVKYIQPMQKGPVGP---------------PFREGKGQYL 64
           GPR   G  GA G  G+   P +  +P   GP+GP                 + GK    
Sbjct: 207 GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 266

Query: 65  EMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG-------MGKPGLHGQPGPAGPP 117
             P P       G PG PG  G RG PG  G  G+ G        G PG +G PGP GP 
Sbjct: 267 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 326

Query: 118 GF-SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT-IPGKP 175
           G     G+ GP G  G  G  GQPG  G PG  G  G  G PG PG  G +G T   G  
Sbjct: 327 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386

Query: 176 GAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPA 234
           GAQG  G PG  G PGP G  G PG  G+ G  G  G PG+ GAPG  G  GPPG  G  
Sbjct: 387 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446

Query: 235 G-LGKPGLDGLPGAPGDKGESGPPGVPGP------------------RGEPGAVGPKGPP 275
           G LG  G  G PG  G KGE GP G PGP                  RGEPG VGP GPP
Sbjct: 447 GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506

Query: 276 GVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-------GMPGLPGPK---G 325
           G    G PG  G PG  G +G KG PG RGP GL GP G        G PGLPG +   G
Sbjct: 507 GER--GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTG 564

Query: 326 DRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385
             G AG  G +G  G PGEDG PG  GPQG  G PG+ G  G  G  G PG  GE G  G
Sbjct: 565 RPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPG 624

Query: 386 PPGVPGIRGDQGPSGLAGKP------------GVPGERGLPGAHGPPGPTGPKGEPGFTG 433
            PG+ G+ G  G +G AG P            G PG  G  G  GPPGP G  G+PG  G
Sbjct: 625 APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG 684

Query: 434 RPGGPGVAGALGQKGDLGLPGQ------PGLRGPSGI---PGLQGPAGPIGPQGLPGLKG 484
            PG  G  G +G +G+ G PG+       GL+GP G+   PG  GP G  GP G PG +G
Sbjct: 685 VPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG 744

Query: 485 EPGLPGPPGE----------GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPG 534
            PGL G PGE          G  G+ G  GP G PG  G  G+TGP GPPGP G  G  G
Sbjct: 745 PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG 804

Query: 535 AFDETGIAGLHLPNGGVEGA 554
                G AG    + G  GA
Sbjct: 805 EVGPPGPAG----SAGARGA 820



 Score =  410 bits (1055), Expect = e-114
 Identities = 246/536 (45%), Positives = 274/536 (51%), Gaps = 74/536 (13%)

Query: 69  PLLPMDLKGEPGPPGKPGPRGPP-------GPPGFPGKPG----MGKPGLHGQPGPAGPP 117
           P+ P DL    G PG  G +G P       GP G PG  G     G  G  G  G  G P
Sbjct: 87  PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP 146

Query: 118 GFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGD-------------------------- 151
           G    G+ G PG PG  GPPG PG  G PG+ G+                          
Sbjct: 147 G--PRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204

Query: 152 -QGLRGPPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG 209
             G RGPPGP G PGP G    PG+PG  GV GP G +G PGP G+PG  G+ G  G   
Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK-- 262

Query: 210 VGQPGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGL---PGAPGDKGES------GPPGV 259
            G+ G PG  G  G PG PGLPG  G  G PGLDG     GAPG KGES      G PG 
Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322

Query: 260 PGPRGEPGAVGPKGPPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG- 314
            GPRG PG  G  GP G  G     G PG AG PGP GP+G  G PG  G  G  GPTG 
Sbjct: 323 MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 382

Query: 315 YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGP 374
            G  G  GP+G+ G  G PG  G  G PG DG PG +G     G PG+ G+ G PG RGP
Sbjct: 383 RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS---AGAPGIAGAPGFPGPRGP 439

Query: 375 PGPKGEAGPGGP------PGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGE 428
           PGP+G  GP GP      PG+ G +G+QGP    G+PG  G +G PG  G  G  G +GE
Sbjct: 440 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPK---GEPGPAGPQGAPGPAGEEGKRGARGE 496

Query: 429 PGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGL 488
           PG  G  G PG  GA G +   G PGQ GL GP G PG +GP+G  GP+G  G  G PG 
Sbjct: 497 PGGVGPIGPPGERGAPGNR---GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 553

Query: 489 PGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAG 543
           PG PG  G  G PG AGP G  G  G+PG  G PGPPGP G  G PG     G  G
Sbjct: 554 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 609



 Score =  344 bits (882), Expect = 2e-94
 Identities = 223/511 (43%), Positives = 250/511 (48%), Gaps = 68/511 (13%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP+   G  G  G  G AP K       GP+GPP   G         P  P    G  G 
Sbjct: 762  GPKGDRGDVGEKGPEG-APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820

Query: 82   PGKPGPRGPPGPPGFPGKPGM-GKPGLHGQ------------PGPAGPPGF----SRMGK 124
            PG+ G  GPPGP GF G PG  G+PG  G+            PGP GP G        G 
Sbjct: 821  PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 880

Query: 125  AGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPP 184
             GP G  G  GPPG  G  G  G  G  G  G PGPPG PGPSG    G  GA+G  GPP
Sbjct: 881  TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD--GPKGARGDSGPP 938

Query: 185  GFQGEPGPQGEPGPPGDRGLKGDNG-------------VGQPGLPGAPGQGGAPGPPGLP 231
            G  GEPG QG  GPPG++G  GD+G              GQ G+ G PGQ G  G PGLP
Sbjct: 939  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998

Query: 232  GPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPG 290
            GP+G  +PG  G PGA GD+G  GP G PG  G  G  G +G PG DG  G  GAAG+ G
Sbjct: 999  GPSG--EPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056

Query: 291  PQGPSGAKGEPGTRGPPGLIGPTG-------YGMPGLPGPKGDRGPAGVPGLLGDRGEPG 343
             +G +GA G PG  GPPG  GP G        G  G  GP G  GPAG  G+ G +G  G
Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116

Query: 344  EDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAG 403
            + GE GE G +GL G  G  G  GLPG   PPGP G+ G  GP G  G RG  GP G +G
Sbjct: 1117 DKGEAGEPGERGLKGHRGFTGLQGLPG---PPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1173

Query: 404  KPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGP-- 461
            K G     G+PG  GPPGP G  GE G  G PG PG             PG PG  GP  
Sbjct: 1174 KDGA---NGIPGPIGPPGPRGRSGETGPAGPPGNPGP------------PGPPGPPGPGI 1218

Query: 462  --SGIPGLQGPAGPIGPQGLPGLKGEPGLPG 490
              S   GL GP    GP  L  ++ +    G
Sbjct: 1219 DMSAFAGL-GPREK-GPDPLQYMRADQAAGG 1247



 Score =  141 bits (356), Expect = 2e-33
 Identities = 92/229 (40%), Positives = 105/229 (45%), Gaps = 41/229 (17%)

Query: 374 PPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPG----VPGERGLPGAHGPPGPTGPKGEP 429
           P  P GE  P  P  +    G  GP G  G+PG    + G +G PG  GP G  GP+G+ 
Sbjct: 78  PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137

Query: 430 GFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGL---------------------- 467
           G  G  G PG  G  G+ G  G PG PG  GP G PGL                      
Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 197

Query: 468 --QGPAGPIGPQGLPGLKGEP------GLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGIT 518
             QGP GP+GP+G PG  G P      G PG PGE G +G  G  GP GPPG PG  G  
Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 257

Query: 519 GPPGPPGPPGPPGAPGAFDETGIAGL-----HLPNGGVEGAVLGKGGKP 562
           G PG  G  GPPG  GA    G  GL     H    G++GA  G+ G P
Sbjct: 258 GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA-KGEAGAP 305



 Score =  115 bits (288), Expect = 1e-25
 Identities = 82/200 (41%), Positives = 89/200 (44%), Gaps = 43/200 (21%)

Query: 413 LPGAHGPPGPTGPKGEPG----FTGRPGGPGVAGALGQ---------KGDLGLPGQPGLR 459
           L  A G PGP G KGEPG      G  G PG  G  G+         KG+ G PG  G  
Sbjct: 93  LATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 152

Query: 460 GPSGIPGLQGPAGPIGPQGLPGL------------------------KGEPGLPGPPG-E 494
           G  G PG  GP GP GP G PGL                        +G  G  GP G  
Sbjct: 153 GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212

Query: 495 GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVE 552
           G AG PG  G  G PG PG PG++GP GP GPPGPPG PG   E G  G     G  G +
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 553 GAVLGKGGKPQFGLGELSAH 572
           GA  G  G P  GL  +  H
Sbjct: 273 GA-RGFPGTP--GLPGVKGH 289



 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 57/140 (40%), Positives = 65/140 (46%), Gaps = 24/140 (17%)

Query: 440 VAGALGQKGDLGLPGQPG----LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEG 495
           +A A GQ G  G  G+PG    + GP G PG QGPAG  GP+G  G KGE G PGP   G
Sbjct: 93  LATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGP--RG 150

Query: 496 RAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAV 555
           R GEPGT                  PG PGPPGPPG PG     G     +  G  E A 
Sbjct: 151 RDGEPGT------------------PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192

Query: 556 LGKGGKPQFGLGELSAHATP 575
             + G  Q  +G +     P
Sbjct: 193 GAQLGVMQGPMGPMGPRGPP 212


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  441 bits (1135), Expect = e-124
 Identities = 274/630 (43%), Positives = 316/630 (50%), Gaps = 65/630 (10%)

Query: 23   GPRASSGG----GAGGAAGYAPVKYI--QPMQKGPVGPPFREGKGQYLEMPLP---LLPM 73
            GP+   G     GA G AG    +    +P   GP+GPP   G       P       P 
Sbjct: 399  GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 458

Query: 74   DLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSRMGKAGPPGLPG 132
               GE GP G  GP+G  G PG PG+PG+ G  GL G+PG AGP G  ++G +G PG  G
Sbjct: 459  GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG--KVGPSGAPGEDG 516

Query: 133  KVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGP 192
            + GPPG  G RG+PG+ G  G +G  G PG  G  G+  PG PG +G+PG  G  G  GP
Sbjct: 517  RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL--PGAPGLRGLPGKDGETGAAGP 574

Query: 193  QGEPGPPGDRGLKGDNGV----GQPGLPGAPGQGGAPGPPGLPGPAGL----------GK 238
             G  GP G+RG +G  G     G PG PG PG+GG PG  G+PG AG           G 
Sbjct: 575  PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634

Query: 239  PGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV----GVPG---AAGLPGP 291
            PG  G PGA G +G  G PG PG  G  GA GP GPPG  G     G+PG   AAG+ GP
Sbjct: 635  PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 694

Query: 292  QGPSGAKGEPGTRGPPG------LIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGE 344
            +G  G  GE G  G PG      L GP G  G  G  G KG+ GP G  G  G RG PGE
Sbjct: 695  KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 754

Query: 345  DGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGK 404
             GE G  GP G  GPPG  G  G  G +G  G KG+AG  GP G  G  G QGP+G+ G 
Sbjct: 755  RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 814

Query: 405  PGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI 464
             G  G +G PGA G PG  G  G PG  G PG PG  G  G+ G  G  G  G  G +G 
Sbjct: 815  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874

Query: 465  PGLQGPAGPIGPQGLPGLKGEPGLPGPPG----------------EGRAGEPGTAGPTGP 508
            PGLQGPAGP G +G PG  G  G  GPPG                 G  G PG  GP+G 
Sbjct: 875  PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 934

Query: 509  PGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKPQFGL 566
            PG  G+PG +G  GPPGP GPPG  G   E G  G    +G  G +GA   KG +     
Sbjct: 935  PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR----- 989

Query: 567  GELSAHATPAFTAVLTSPFPASGMPVKFDR 596
            GE  A   P       SP PA     + DR
Sbjct: 990  GETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019



 Score =  433 bits (1113), Expect = e-121
 Identities = 272/607 (44%), Positives = 298/607 (49%), Gaps = 62/607 (10%)

Query: 11  LLLLLLVLVLGC-GPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREG---------- 59
           LL LL+  VL C G      G  G       +K I     GP GPP  +G          
Sbjct: 12  LLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIV----GPKGPPGPQGPAGEQGPRGD 67

Query: 60  KGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG-------------MGKPG 106
           +G   E   P  P    GEPG PG PGP GPPGPPG PG  G              G   
Sbjct: 68  RGDKGEKGAPG-PRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ 126

Query: 107 LHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGP 166
           L    GP GP G    G  GP G PG  G  G PG  GEPG+ G  G RGPPGPPG PG 
Sbjct: 127 LGVMQGPMGPMG--PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184

Query: 167 SGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKG-DNGVGQPGLPGAPGQGGA 224
            G    PGK G +G PGP G +G PG  G PG  G RG  G D   G+ G PG  G+ G+
Sbjct: 185 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244

Query: 225 PGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GV 282
           PG  G PGP G  G PG  G  G  G  G  G  G PGP G PG VGP G PG  G  G 
Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304

Query: 283 PGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGE 341
            G AG  G +GP GA+G  G  G PG  GP G  G PG  G  G +G AG PG+ G  G 
Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364

Query: 342 PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGL 401
           PG  G PG QG  G  GP G  G  G+ G +G  GPKGE GP GP G PG  G++G  G 
Sbjct: 365 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 424

Query: 402 AGKPG------VPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ 455
            G+PG       PGERG PG  G PG  G  G  G  G  G  G+AG  G  GD G PG+
Sbjct: 425 RGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 484

Query: 456 PGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGS 514
           PGL G  G+ G  G AGP G  G  G  GE G PGPPG +G  G+PG  G  GP G  G 
Sbjct: 485 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 544

Query: 515 PGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGA--------------V 555
           PG  G  G PG PG  G PG   ETG AG   P G     G +GA               
Sbjct: 545 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 604

Query: 556 LGKGGKP 562
            G+GGKP
Sbjct: 605 PGEGGKP 611



 Score =  427 bits (1097), Expect = e-119
 Identities = 278/625 (44%), Positives = 314/625 (50%), Gaps = 118/625 (18%)

Query: 31   GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 90
            GA G  G A  K + P   G  G P ++G+      P P  P   +GE G PG  G +G 
Sbjct: 540  GANGEPGKAGEKGL-PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 598

Query: 91   PGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGE----- 145
            PGPPG PG+ G  KPG  G PG AG PG   +G  G  G PG+ G PG  GL+G      
Sbjct: 599  PGPPGPPGEGG--KPGDQGVPGEAGAPGL--VGPRGERGFPGERGSPGAQGLQGPRGLPG 654

Query: 146  -PGIRGDQGLRGPPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQG---EPGPQGEPG--- 197
             PG  G +G  GP GPPG  GP G+  +PG+ GA G+ GP G +G   E GP+G PG   
Sbjct: 655  TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 714

Query: 198  ---------PPGDRGLKGDNG-VGQPGLPGAPGQGGAPGP---PGLPGPAGL-GKPGLDG 243
                     PPG  G  G+ G VG PG  G+ G  GAPG     G PGPAG  G PG DG
Sbjct: 715  GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADG 774

Query: 244  LPGAPGDKGESGPPG---VPGPRGEPGAVGPKGPPGVDGV-------GVPGAAGLPGPQG 293
             PGA G++GE+G  G    PGP+G  GA GP+GP GV G        G PGA G PG  G
Sbjct: 775  QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG 834

Query: 294  PSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGP---AGVPGLLGDRGEPGEDGEPGE 350
              G  G  G  GPPG  GP+G   P   G +GD GP   AG PGL G  G PGE GEPG+
Sbjct: 835  RVGPPGSNGNPGPPGPPGPSGKDGP--KGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 892

Query: 351  QGPQGLGGPPGLPGSAG------LPGRRGP------PGPKGEAGPGGPPGVPGIRGDQGP 398
             GP G  GPPG  G AG      LPG+RG       PGP GE G  G PG  G RG  GP
Sbjct: 893  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952

Query: 399  ---SGLAGKPGVPGERGLPGAHGPPG------------PTGPKGEPGFTGRPGGPGVAGA 443
                GL G  G PG  G PGA GPPG             TG  G PG  G PG PG AG 
Sbjct: 953  VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012

Query: 444  LGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG---------------L 488
             G++GD G  G  G  GPSG  G +G  GP GP+G  G  GEPG               L
Sbjct: 1013 TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGL 1072

Query: 489  PGPPG----EGRAGEPGTAGPTGPPG---------VPGSPGITGPPGP------------ 523
            PGPPG    +G +G  G +GP GPPG           G PG  GPPGP            
Sbjct: 1073 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132

Query: 524  ---PGPPGPPGAPG-AFDETGIAGL 544
               PGPPGPPG PG   D +  AGL
Sbjct: 1133 PGNPGPPGPPGPPGPGIDMSAFAGL 1157



 Score =  344 bits (882), Expect = 2e-94
 Identities = 223/511 (43%), Positives = 250/511 (48%), Gaps = 68/511 (13%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP+   G  G  G  G AP K       GP+GPP   G         P  P    G  G 
Sbjct: 693  GPKGDRGDVGEKGPEG-APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751

Query: 82   PGKPGPRGPPGPPGFPGKPGM-GKPGLHGQ------------PGPAGPPGF----SRMGK 124
            PG+ G  GPPGP GF G PG  G+PG  G+            PGP GP G        G 
Sbjct: 752  PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 811

Query: 125  AGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPP 184
             GP G  G  GPPG  G  G  G  G  G  G PGPPG PGPSG    G  GA+G  GPP
Sbjct: 812  TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD--GPKGARGDSGPP 869

Query: 185  GFQGEPGPQGEPGPPGDRGLKGDNG-------------VGQPGLPGAPGQGGAPGPPGLP 231
            G  GEPG QG  GPPG++G  GD+G              GQ G+ G PGQ G  G PGLP
Sbjct: 870  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929

Query: 232  GPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPG 290
            GP+G  +PG  G PGA GD+G  GP G PG  G  G  G +G PG DG  G  GAAG+ G
Sbjct: 930  GPSG--EPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987

Query: 291  PQGPSGAKGEPGTRGPPGLIGPTG-------YGMPGLPGPKGDRGPAGVPGLLGDRGEPG 343
             +G +GA G PG  GPPG  GP G        G  G  GP G  GPAG  G+ G +G  G
Sbjct: 988  DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047

Query: 344  EDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAG 403
            + GE GE G +GL G  G  G  GLPG   PPGP G+ G  GP G  G RG  GP G +G
Sbjct: 1048 DKGEAGEPGERGLKGHRGFTGLQGLPG---PPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1104

Query: 404  KPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGP-- 461
            K G     G+PG  GPPGP G  GE G  G PG PG             PG PG  GP  
Sbjct: 1105 KDGA---NGIPGPIGPPGPRGRSGETGPAGPPGNPGP------------PGPPGPPGPGI 1149

Query: 462  --SGIPGLQGPAGPIGPQGLPGLKGEPGLPG 490
              S   GL GP    GP  L  ++ +    G
Sbjct: 1150 DMSAFAGL-GPREK-GPDPLQYMRADQAAGG 1178



 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 54/134 (40%), Positives = 61/134 (45%), Gaps = 24/134 (17%)

Query: 446 QKGDLGLPGQPG----LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPG 501
           Q G  G  G+PG    + GP G PG QGPAG  GP+G  G KGE G PGP   GR GEPG
Sbjct: 30  QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGP--RGRDGEPG 87

Query: 502 TAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGK 561
           T                  PG PGPPGPPG PG     G     +  G  E A   + G 
Sbjct: 88  T------------------PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129

Query: 562 PQFGLGELSAHATP 575
            Q  +G +     P
Sbjct: 130 MQGPMGPMGPRGPP 143


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  441 bits (1134), Expect = e-123
 Identities = 284/644 (44%), Positives = 326/644 (50%), Gaps = 142/644 (22%)

Query: 23   GPRASSGG-------GAGGAAG-YAPVKYIQPMQKGPVGPPFREG----KGQYLEMPL-- 68
            GP+ +SGG       G  G  G   PV +  P  KGP GPP ++G     GQ  E     
Sbjct: 913  GPKGTSGGDGPPGPPGERGPQGPQGPVGF--PGPKGPPGPPGKDGLPGHPGQRGETGFQG 970

Query: 69   ---PLLPMDLKGEPGPPGKPGP---RGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSR 121
               P  P  + G  GP G+ GP   RG PGPPG PG+ G+ G  G  G  G  GP G S 
Sbjct: 971  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS- 1029

Query: 122  MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG-------ITIPGK 174
             GK GP GL G  G  G PG +G PG++G +G +GPPGP G PG  G       I +PG+
Sbjct: 1030 -GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1088

Query: 175  PGAQGVPGPPGFQGEPG---------------PQGEPGPPGDRGLKGDNG----VGQPGL 215
            PG QG PGP G +G PG               P G PGP G  G  G++G    +G+PG 
Sbjct: 1089 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1148

Query: 216  PGAPG---QGGAPGPPGLPGPAGL-------GKPG------------------------- 240
             G+ G   + G PGPPGL GP G        G+PG                         
Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1208

Query: 241  --LDGLPGAPGDKGESG------PPGVPGPRGEPG---AVGPKGPPG----VDGVGV--- 282
              L GLPG PG+KGE+G      PPG PGPRG  G   A GP+GPPG    V GVG    
Sbjct: 1209 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268

Query: 283  PGAAGLPGPQG------------------PSGAKGEPGTRGPPGLIGPTG----YGMPGL 320
            PG AG PGP G                  P GA G PG +GPPG  GP G     G PG 
Sbjct: 1269 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1328

Query: 321  PGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPG------RRGP 374
            PGP G+ GPAG  G+ GD+GE G+ G+PG  GP G  GPPG PG  G PG      R+G 
Sbjct: 1329 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1388

Query: 375  PGPKGEAGPGGPPGVPGIRGDQGPS------GLAGKPGVPGERGLPGA---HGPPGPTGP 425
             G KGEAG  GPPG  G  G QGP+      GL G PG  GE+GLPGA    GPPGP GP
Sbjct: 1389 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1448

Query: 426  KGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGE 485
             G PG  G PG  G  G  G  G +G PG+ G +G  G+PG QG  G  G  G+PG  G 
Sbjct: 1449 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1508

Query: 486  PGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPG 528
             G PGPPG  G  G  G  G TGP G  G  G+ GPPG PGPPG
Sbjct: 1509 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  433 bits (1114), Expect = e-121
 Identities = 274/603 (45%), Positives = 303/603 (50%), Gaps = 66/603 (10%)

Query: 24   PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPG 83
            P A+   GA G AG    +     Q+GP GP    G       P P       G PGPPG
Sbjct: 873  PGANGEKGARGVAGKPGPRG----QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG 928

Query: 84   KPGPRGPPGPPGFPGKPGM----GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGP--- 136
            + GP+GP GP GFPG  G     GK GL G PG  G  GF   GK GPPG  G VGP   
Sbjct: 929  ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ--GKTGPPGPGGVVGPQGP 986

Query: 137  ---------------PGQPGLRGEPGIRGDQGLRGPPGPPGLPG---PSGIT-IPGKPGA 177
                           PG PG +G PG  G +G +G PGP G+ G   P+G+   PG+ G 
Sbjct: 987  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1046

Query: 178  QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQP-GLPGAPGQGGAPGPPG------- 229
             G  G PG +G  GPQG PGP G  G +G  G   P GLPG PG  G PGP G       
Sbjct: 1047 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1106

Query: 230  -----------LPGPAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGV 277
                       + GP GL G  G  G PG  GDKGE G PG  G +G+ G  GP GPPG+
Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166

Query: 278  DG-VGVPGAAG---LPGP---QGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKG---D 326
             G VG PG AG    PGP   QG  G KG+ G RG PG  GP G  G+PG PG KG   D
Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1226

Query: 327  RGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGP 386
             GP G PG  G RG  G +G  G QGP G  G  G  G  G PG  G PGP GEAG GGP
Sbjct: 1227 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1286

Query: 387  PGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQ 446
             G  G +G+ GP G AG PG  G  G  G  G PGP G  G+PG  G PG  G  G  G 
Sbjct: 1287 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1346

Query: 447  KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTAGP 505
            KG+ G PGQPG  GPSG  G  GP G  GP G  G +G  G  G  GE G  G PG  GP
Sbjct: 1347 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1406

Query: 506  TGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKPQ 563
             GP G  G PG  G  G PGP G  G PGA  + G  G   P G  G++G    KG K  
Sbjct: 1407 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1466

Query: 564  FGL 566
             GL
Sbjct: 1467 PGL 1469



 Score =  422 bits (1085), Expect = e-118
 Identities = 264/605 (43%), Positives = 305/605 (50%), Gaps = 99/605 (16%)

Query: 48   QKGPVGPPFREGKGQYLEMPLP-------LLPMDLKGEPGPPGKPGPRGPPGPPGFPGKP 100
            +KG  G P     G  +E P         + P  L+G  GPPG PG RGPPG PG PG  
Sbjct: 436  EKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGAD 495

Query: 101  GM-GKPGL-------HGQPGPAGPP------------GFSRMGKAGPP------GLPGKV 134
            G+ G PG        +G  G  GP               +R+   GPP      G PG V
Sbjct: 496  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 555

Query: 135  GPPGQPGLRGE---PGIRGDQGLRGPPGPPGLPG-------PSGITIPGKPGAQ------ 178
            G PG  G +GE   PG +G +G++GPPGP G PG         G  +PG+PGA+      
Sbjct: 556  GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 615

Query: 179  ---GVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPA 234
               G+PG  G +GE GPQG PGPPGD G++G++G +G  GLPG  G  G  GP G PG  
Sbjct: 616  GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 675

Query: 235  GLGKPGLDGLPGAPGDK------GESGPPGV---PGPRGEPGAVGPKGPPGVDG-VGVPG 284
              G+PG+ G+ G PG K      GE GPPG    PGP+G PG  GP GPPG  G  G PG
Sbjct: 676  --GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG 733

Query: 285  AAGLPGPQGP------SGAKGEPGTRGPPGLIGPTGY----------GMPGLPGPKGDRG 328
             AGLPG  GP       G  GE G  GPPG  GP GY          G+ GL G KG++G
Sbjct: 734  LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 793

Query: 329  PAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPG 388
              G PG  GD G  G+ GE G+ GP+G  GP G  G AG  G  GP G  GE G  G PG
Sbjct: 794  EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 853

Query: 389  VPGIRGDQGPSGLAGKPGVPGER---------GLPGAHGPPGPTGPKGEPGFTGRPGGPG 439
            +PG  G QGP G  G PG PG           G PG  G  GPTGP+G  G  G  G PG
Sbjct: 854  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 913

Query: 440  VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAG 498
              G  G  G  G PG+ G +GP G  G  GP GP GP G  GL G PG  G  G +G+ G
Sbjct: 914  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973

Query: 499  EP---GTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAV 555
             P   G  GP GP G  G  G  G PGPPGPPG  G PGA  + G  G   P G     +
Sbjct: 974  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG-----I 1028

Query: 556  LGKGG 560
             GK G
Sbjct: 1029 SGKDG 1033



 Score =  417 bits (1073), Expect = e-116
 Identities = 262/591 (44%), Positives = 291/591 (49%), Gaps = 87/591 (14%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPG---FPGKPGM-GKP 105
            GPVG P   G       P P  P  ++G PGP GKPG RG PG  G    PG+PG  G  
Sbjct: 553  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 612

Query: 106  GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG 165
            G  G PG  G  G    G+ GP G PG   PPG  G+RGE G  G +GL G  GP GL G
Sbjct: 613  GFDGLPGLPGDKG--HRGERGPQGPPG---PPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 667

Query: 166  PSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGA 224
            P G    PG+PG  GV GPPG +G  GPQGEPGPPG +G  G  G+  PG  G  G  G 
Sbjct: 668  PRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGE 725

Query: 225  PGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGV---PGPRGEPGAVGPKGPPGVDGV- 280
             GP G PG AGL  PG DG PG PG +G+SG  G    PGP+G  G  GP+G  G DGV 
Sbjct: 726  KGPQGKPGLAGL--PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR 783

Query: 281  ------GVPGAAGLPGPQGPSGAKG------------EPGTRGPPGLIGPTGY------- 315
                  G  G  G PG +G  G KG            E G  GP G  GPTG        
Sbjct: 784  GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQA 843

Query: 316  ---------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSA 366
                     G+PG PG +G +G  G PG  G  GE G  G  G+ GP+G  GP G  GS 
Sbjct: 844  GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 903

Query: 367  GLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPK 426
            G  G  G PGPKG +G  GPPG PG RG QGP G  G PG  G  G PG  G PG  G +
Sbjct: 904  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 963

Query: 427  GEPGFTGRPGGPGVAGALGQK---------------------GDLGLPGQPGLRGPSGIP 465
            GE GF G+ G PG  G +G +                     G+ GLPG  G  G  G P
Sbjct: 964  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1023

Query: 466  GLQGPAGPIGPQGLPGLKGEPGLPGPPG----EGRAGEPGTAGPTGPPGVPGSPGITGPP 521
            G QG +G  GP GL G  GE GLPG  G    +G  G  G  GP G PG  GS G  GP 
Sbjct: 1024 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1083

Query: 522  GPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGAV-----LGKGGKP 562
            G PG PGP G PG   E G  G   P G     GV+G V      G  G P
Sbjct: 1084 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1134



 Score =  402 bits (1034), Expect = e-112
 Identities = 270/681 (39%), Positives = 313/681 (45%), Gaps = 162/681 (23%)

Query: 23   GPRASSGG-GAGGAAGY----APVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKG 77
            GPR + G  G  G AG      P   + P  +G  GPP ++G      +P P  P+   G
Sbjct: 667  GPRGTPGAPGQPGMAGVDGPPGPKGNMGP--QGEPGPPGQQGNPGPQGLPGPQGPIGPPG 724

Query: 78   EPGPPGKPG---------P------------------RGPPGPPGFPGKPGM-------G 103
            E GP GKPG         P                   GP GP G+PG  G+       G
Sbjct: 725  EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 784

Query: 104  KPGLHGQPGPAGPPGF----------------SRMGKAGPPGLPGKVGPPGQPGLRGEPG 147
              G  G+ G  G PGF                   G+ GP G  G+ GP G PG  G+ G
Sbjct: 785  LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 844

Query: 148  IRGDQGLRGPPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKG 206
             +G  G+ G PG PG  GP G T  PG PGA G  G  G  G+PGP+G+ GP G RG +G
Sbjct: 845  EKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 904

Query: 207  DNG-VGQPGLPGAPGQGGAPGPP------------GLPGPAG-LGKPGLDGLPGAPGDKG 252
              G  G+PG  G  G  G PGPP            G PGP G  G PG DGLPG PG +G
Sbjct: 905  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 964

Query: 253  ES---------------------------------GPPGVPGPRGEPGAV---GPKGPPG 276
            E+                                 GPPG PG +G PGA    G KG PG
Sbjct: 965  ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1024

Query: 277  VDGV----------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG----------YG 316
              G+          G PG  GLPG QG  G KG  G +GPPG +G  G           G
Sbjct: 1025 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1084

Query: 317  MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS---------AG 367
            +PG PGP+G  GPAG  G  G++G  G  G  G QGP GL GP G  GS          G
Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1144

Query: 368  LPGRRGPPGPKGEAGPGGPPGV------PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPG 421
             PG++G  G KGE GP GPPG+      PGI G  G  G  G+ G+ G++G  GA G PG
Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204

Query: 422  PTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG 481
            P GP G  G  G PG  G  G +G  G  G PG  G +GP+G  G QGP G +G  G  G
Sbjct: 1205 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1264

Query: 482  LKGEP---GLPGPPGE-------------GRAGEPGTAGPTGPPGVPGSPGITGPPGP-- 523
             KGEP   G PGPPGE             G AG PG AGP G  G PG  G  G PGP  
Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1324

Query: 524  -PGPPGPPGAPGAFDETGIAG 543
             PG PGPPG PG   + G+ G
Sbjct: 1325 FPGDPGPPGEPGPAGQDGVGG 1345



 Score =  375 bits (962), Expect = e-103
 Identities = 248/604 (41%), Positives = 280/604 (46%), Gaps = 135/604 (22%)

Query: 69  PLLPMDLKGEPGPPGKP-------GPRGPPGPPGFPGKPGMGKPGL--HGQPGPAGPPGF 119
           P  P + +  PG P +           G  G  G  G+P + +PG+   G PGPAGP G 
Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464

Query: 120 SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGA-- 177
                 GPPGL G  GPPG PG RG            PPG PGLPG  G  +PG PG   
Sbjct: 465 M-----GPPGLQGPTGPPGDPGDRG------------PPGRPGLPGADG--LPGPPGTML 505

Query: 178 ----------------------------------QGVPGPPGFQGEPGP----------- 192
                                             +G PGP G  G PGP           
Sbjct: 506 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 565

Query: 193 -QGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD 250
             G+PGP G RG++G  G  G+PG  G PG  G  G PG PG    G  G DGLPG PGD
Sbjct: 566 ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG--AKGDRGFDGLPGLPGD 623

Query: 251 K---GESGPPGVPGP------RGEPGAVGPKGPPGVDGV-------GVPGAAGLP----- 289
           K   GE GP G PGP      RGE G +GP+G PG  G        G PGA G P     
Sbjct: 624 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 683

Query: 290 ----------GPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGD 338
                     GPQG  G  G+ G  GP GL GP G  G PG  GP+G  G AG+PG  G 
Sbjct: 684 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 743

Query: 339 RGEPGEDGEPGEQ---GPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGD 395
            G PG++G+ GE+   GP G  GP G PG  G+ G  G  G KG  G  G  G PG +GD
Sbjct: 744 PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 803

Query: 396 QGPSGLAGKPGVPGERGLPGAHGP---------PGPTGPKGEPGFTGRPGGPGVAGALGQ 446
            G  G  G+ G  G RG  G  GP         PGP+G  GE G  G PG PG  G  G 
Sbjct: 804 MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP 863

Query: 447 KGDLGLPGQP------GLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP----GEGR 496
           KG  G PG P      G RG +G PG +G  GP GP+G  G +G  G PGP     G+G 
Sbjct: 864 KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923

Query: 497 AGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVL 556
            G PG  GP GP G  G PG  GPPGPPG  G PG PG   ETG  G   P G   G V+
Sbjct: 924 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG--PGGVV 981

Query: 557 GKGG 560
           G  G
Sbjct: 982 GPQG 985



 Score =  261 bits (666), Expect = 2e-69
 Identities = 166/405 (40%), Positives = 195/405 (48%), Gaps = 46/405 (11%)

Query: 190 PGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPG 249
           P  +  PG P +  +   +  G     GA G+ G  G P +  P  L    ++G PG  G
Sbjct: 409 PNEEFGPGVPAETDITETSINGH----GAYGEKGQKGEPAVVEPGML----VEGPPGPAG 460

Query: 250 DKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPS----GAKGEPGTRG 305
             G  GPPG+ GP G PG  G +GPPG  G+  PGA GLPGP G         G  G++G
Sbjct: 461 PAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL--PGADGLPGPPGTMLMLPFRYGGDGSKG 518

Query: 306 PP---------GLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL 356
           P           ++      + G PGP G  G  G  G  G  G  GE G+PG QGP+G+
Sbjct: 519 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 578

Query: 357 GGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA 416
            GPPG     G PG+RG PG  G  G  G PG  G RG  G  GL G  G  GERG  G 
Sbjct: 579 QGPPG---PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGP 635

Query: 417 HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGP 476
            GPPG  G +GE G  G  G PG AG  G  G  G PG PG  G +G+ G  GP G +GP
Sbjct: 636 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 695

Query: 477 QGLPGLKGEPGLPGPPG----EGRAGEPGTAGPTGPPGVPGSPGITGPPGPP-------- 524
           QG PG  G+ G PGP G    +G  G PG  GP G PG+ G PG  GPPG P        
Sbjct: 696 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 755

Query: 525 ----GPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFG 565
               GPPGP G  G     G+ G      GV G    KG K + G
Sbjct: 756 KGALGPPGPQGPIGYPGPRGVKGA----DGVRGLKGSKGEKGEDG 796



 Score =  229 bits (585), Expect = 5e-60
 Identities = 159/398 (39%), Positives = 182/398 (45%), Gaps = 95/398 (23%)

Query: 23   GPRASSG----GGAGGAAGYAPVKYIQPMQKGPVG------PPFREGKGQYLEMPLPLLP 72
            GPR   G     G  GA G+       P   GP+G      PP  +G+   +    P  P
Sbjct: 1183 GPRGQQGMFGQKGDEGARGF-------PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1235

Query: 73   MDLKGEPGPPGKPGPRGPPGP------------------PGFPGKPGMGKP-------GL 107
               +G  GP G  GP+GPPG                   PG PG+ G+G P       G 
Sbjct: 1236 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1295

Query: 108  HGQPGPAGPPGFSR-------MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160
             G PG AGPPG           G  GP G PG  GPPG+PG  G+ G+ GD+G  G PG 
Sbjct: 1296 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1355

Query: 161  PGLPGPSGIT-IPGKPGAQGVPG---------------------PPGFQGEPGPQGEPGP 198
            PG PGPSG    PG PG +G PG                     PPG  G  GPQG  G 
Sbjct: 1356 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGK 1415

Query: 199  PGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGL----------GKPGLDGLPGA 247
            PG  GL+G  G VG+ GLPGA GQ G PGP G PG  GL          G PGL GL G 
Sbjct: 1416 PGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1475

Query: 248  PGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGLPGPQGPSGAKGE------ 300
            PG++GE G  G+PG +G PGA G  G PG  G +G PG  GLPGPQGP G KG       
Sbjct: 1476 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1535

Query: 301  ------PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGV 332
                  PG  G PG  G     +P L   K  R   G+
Sbjct: 1536 KGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGM 1573


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  441 bits (1134), Expect = e-123
 Identities = 284/644 (44%), Positives = 326/644 (50%), Gaps = 142/644 (22%)

Query: 23   GPRASSGG-------GAGGAAG-YAPVKYIQPMQKGPVGPPFREG----KGQYLEMPL-- 68
            GP+ +SGG       G  G  G   PV +  P  KGP GPP ++G     GQ  E     
Sbjct: 862  GPKGTSGGDGPPGPPGERGPQGPQGPVGF--PGPKGPPGPPGKDGLPGHPGQRGETGFQG 919

Query: 69   ---PLLPMDLKGEPGPPGKPGP---RGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSR 121
               P  P  + G  GP G+ GP   RG PGPPG PG+ G+ G  G  G  G  GP G S 
Sbjct: 920  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS- 978

Query: 122  MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG-------ITIPGK 174
             GK GP GL G  G  G PG +G PG++G +G +GPPGP G PG  G       I +PG+
Sbjct: 979  -GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037

Query: 175  PGAQGVPGPPGFQGEPG---------------PQGEPGPPGDRGLKGDNG----VGQPGL 215
            PG QG PGP G +G PG               P G PGP G  G  G++G    +G+PG 
Sbjct: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1097

Query: 216  PGAPG---QGGAPGPPGLPGPAGL-------GKPG------------------------- 240
             G+ G   + G PGPPGL GP G        G+PG                         
Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1157

Query: 241  --LDGLPGAPGDKGESG------PPGVPGPRGEPG---AVGPKGPPG----VDGVGV--- 282
              L GLPG PG+KGE+G      PPG PGPRG  G   A GP+GPPG    V GVG    
Sbjct: 1158 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217

Query: 283  PGAAGLPGPQG------------------PSGAKGEPGTRGPPGLIGPTG----YGMPGL 320
            PG AG PGP G                  P GA G PG +GPPG  GP G     G PG 
Sbjct: 1218 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1277

Query: 321  PGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPG------RRGP 374
            PGP G+ GPAG  G+ GD+GE G+ G+PG  GP G  GPPG PG  G PG      R+G 
Sbjct: 1278 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1337

Query: 375  PGPKGEAGPGGPPGVPGIRGDQGPS------GLAGKPGVPGERGLPGA---HGPPGPTGP 425
             G KGEAG  GPPG  G  G QGP+      GL G PG  GE+GLPGA    GPPGP GP
Sbjct: 1338 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1397

Query: 426  KGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGE 485
             G PG  G PG  G  G  G  G +G PG+ G +G  G+PG QG  G  G  G+PG  G 
Sbjct: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1457

Query: 486  PGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPG 528
             G PGPPG  G  G  G  G TGP G  G  G+ GPPG PGPPG
Sbjct: 1458 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  433 bits (1114), Expect = e-121
 Identities = 274/603 (45%), Positives = 303/603 (50%), Gaps = 66/603 (10%)

Query: 24   PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPG 83
            P A+   GA G AG    +     Q+GP GP    G       P P       G PGPPG
Sbjct: 822  PGANGEKGARGVAGKPGPRG----QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG 877

Query: 84   KPGPRGPPGPPGFPGKPGM----GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGP--- 136
            + GP+GP GP GFPG  G     GK GL G PG  G  GF   GK GPPG  G VGP   
Sbjct: 878  ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ--GKTGPPGPGGVVGPQGP 935

Query: 137  ---------------PGQPGLRGEPGIRGDQGLRGPPGPPGLPG---PSGIT-IPGKPGA 177
                           PG PG +G PG  G +G +G PGP G+ G   P+G+   PG+ G 
Sbjct: 936  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995

Query: 178  QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQP-GLPGAPGQGGAPGPPG------- 229
             G  G PG +G  GPQG PGP G  G +G  G   P GLPG PG  G PGP G       
Sbjct: 996  PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055

Query: 230  -----------LPGPAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGV 277
                       + GP GL G  G  G PG  GDKGE G PG  G +G+ G  GP GPPG+
Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115

Query: 278  DG-VGVPGAAG---LPGP---QGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKG---D 326
             G VG PG AG    PGP   QG  G KG+ G RG PG  GP G  G+PG PG KG   D
Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1175

Query: 327  RGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGP 386
             GP G PG  G RG  G +G  G QGP G  G  G  G  G PG  G PGP GEAG GGP
Sbjct: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1235

Query: 387  PGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQ 446
             G  G +G+ GP G AG PG  G  G  G  G PGP G  G+PG  G PG  G  G  G 
Sbjct: 1236 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1295

Query: 447  KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTAGP 505
            KG+ G PGQPG  GPSG  G  GP G  GP G  G +G  G  G  GE G  G PG  GP
Sbjct: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355

Query: 506  TGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKPQ 563
             GP G  G PG  G  G PGP G  G PGA  + G  G   P G  G++G    KG K  
Sbjct: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1415

Query: 564  FGL 566
             GL
Sbjct: 1416 PGL 1418



 Score =  422 bits (1085), Expect = e-118
 Identities = 264/605 (43%), Positives = 305/605 (50%), Gaps = 99/605 (16%)

Query: 48  QKGPVGPPFREGKGQYLEMPLP-------LLPMDLKGEPGPPGKPGPRGPPGPPGFPGKP 100
           +KG  G P     G  +E P         + P  L+G  GPPG PG RGPPG PG PG  
Sbjct: 385 EKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGAD 444

Query: 101 GM-GKPGL-------HGQPGPAGPP------------GFSRMGKAGPP------GLPGKV 134
           G+ G PG        +G  G  GP               +R+   GPP      G PG V
Sbjct: 445 GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 504

Query: 135 GPPGQPGLRGE---PGIRGDQGLRGPPGPPGLPG-------PSGITIPGKPGAQ------ 178
           G PG  G +GE   PG +G +G++GPPGP G PG         G  +PG+PGA+      
Sbjct: 505 GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 564

Query: 179 ---GVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPA 234
              G+PG  G +GE GPQG PGPPGD G++G++G +G  GLPG  G  G  GP G PG  
Sbjct: 565 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 624

Query: 235 GLGKPGLDGLPGAPGDK------GESGPPGV---PGPRGEPGAVGPKGPPGVDG-VGVPG 284
             G+PG+ G+ G PG K      GE GPPG    PGP+G PG  GP GPPG  G  G PG
Sbjct: 625 --GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG 682

Query: 285 AAGLPGPQGP------SGAKGEPGTRGPPGLIGPTGY----------GMPGLPGPKGDRG 328
            AGLPG  GP       G  GE G  GPPG  GP GY          G+ GL G KG++G
Sbjct: 683 LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 742

Query: 329 PAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPG 388
             G PG  GD G  G+ GE G+ GP+G  GP G  G AG  G  GP G  GE G  G PG
Sbjct: 743 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 802

Query: 389 VPGIRGDQGPSGLAGKPGVPGER---------GLPGAHGPPGPTGPKGEPGFTGRPGGPG 439
           +PG  G QGP G  G PG PG           G PG  G  GPTGP+G  G  G  G PG
Sbjct: 803 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 862

Query: 440 VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAG 498
             G  G  G  G PG+ G +GP G  G  GP GP GP G  GL G PG  G  G +G+ G
Sbjct: 863 PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922

Query: 499 EP---GTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAV 555
            P   G  GP GP G  G  G  G PGPPGPPG  G PGA  + G  G   P G     +
Sbjct: 923 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG-----I 977

Query: 556 LGKGG 560
            GK G
Sbjct: 978 SGKDG 982



 Score =  417 bits (1073), Expect = e-116
 Identities = 262/591 (44%), Positives = 291/591 (49%), Gaps = 87/591 (14%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPG---FPGKPGM-GKP 105
            GPVG P   G       P P  P  ++G PGP GKPG RG PG  G    PG+PG  G  
Sbjct: 502  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 561

Query: 106  GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG 165
            G  G PG  G  G    G+ GP G PG   PPG  G+RGE G  G +GL G  GP GL G
Sbjct: 562  GFDGLPGLPGDKG--HRGERGPQGPPG---PPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 616

Query: 166  PSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGA 224
            P G    PG+PG  GV GPPG +G  GPQGEPGPPG +G  G  G+  PG  G  G  G 
Sbjct: 617  PRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGE 674

Query: 225  PGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGV---PGPRGEPGAVGPKGPPGVDGV- 280
             GP G PG AGL  PG DG PG PG +G+SG  G    PGP+G  G  GP+G  G DGV 
Sbjct: 675  KGPQGKPGLAGL--PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR 732

Query: 281  ------GVPGAAGLPGPQGPSGAKG------------EPGTRGPPGLIGPTGY------- 315
                  G  G  G PG +G  G KG            E G  GP G  GPTG        
Sbjct: 733  GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQA 792

Query: 316  ---------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSA 366
                     G+PG PG +G +G  G PG  G  GE G  G  G+ GP+G  GP G  GS 
Sbjct: 793  GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 852

Query: 367  GLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPK 426
            G  G  G PGPKG +G  GPPG PG RG QGP G  G PG  G  G PG  G PG  G +
Sbjct: 853  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 912

Query: 427  GEPGFTGRPGGPGVAGALGQK---------------------GDLGLPGQPGLRGPSGIP 465
            GE GF G+ G PG  G +G +                     G+ GLPG  G  G  G P
Sbjct: 913  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972

Query: 466  GLQGPAGPIGPQGLPGLKGEPGLPGPPG----EGRAGEPGTAGPTGPPGVPGSPGITGPP 521
            G QG +G  GP GL G  GE GLPG  G    +G  G  G  GP G PG  GS G  GP 
Sbjct: 973  GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1032

Query: 522  GPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGAV-----LGKGGKP 562
            G PG PGP G PG   E G  G   P G     GV+G V      G  G P
Sbjct: 1033 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1083



 Score =  402 bits (1034), Expect = e-112
 Identities = 270/681 (39%), Positives = 313/681 (45%), Gaps = 162/681 (23%)

Query: 23   GPRASSGG-GAGGAAGY----APVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKG 77
            GPR + G  G  G AG      P   + P  +G  GPP ++G      +P P  P+   G
Sbjct: 616  GPRGTPGAPGQPGMAGVDGPPGPKGNMGP--QGEPGPPGQQGNPGPQGLPGPQGPIGPPG 673

Query: 78   EPGPPGKPG---------P------------------RGPPGPPGFPGKPGM-------G 103
            E GP GKPG         P                   GP GP G+PG  G+       G
Sbjct: 674  EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 733

Query: 104  KPGLHGQPGPAGPPGF----------------SRMGKAGPPGLPGKVGPPGQPGLRGEPG 147
              G  G+ G  G PGF                   G+ GP G  G+ GP G PG  G+ G
Sbjct: 734  LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 793

Query: 148  IRGDQGLRGPPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKG 206
             +G  G+ G PG PG  GP G T  PG PGA G  G  G  G+PGP+G+ GP G RG +G
Sbjct: 794  EKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 853

Query: 207  DNG-VGQPGLPGAPGQGGAPGPP------------GLPGPAG-LGKPGLDGLPGAPGDKG 252
              G  G+PG  G  G  G PGPP            G PGP G  G PG DGLPG PG +G
Sbjct: 854  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 913

Query: 253  ES---------------------------------GPPGVPGPRGEPGAV---GPKGPPG 276
            E+                                 GPPG PG +G PGA    G KG PG
Sbjct: 914  ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 973

Query: 277  VDGV----------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG----------YG 316
              G+          G PG  GLPG QG  G KG  G +GPPG +G  G           G
Sbjct: 974  PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1033

Query: 317  MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS---------AG 367
            +PG PGP+G  GPAG  G  G++G  G  G  G QGP GL GP G  GS          G
Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1093

Query: 368  LPGRRGPPGPKGEAGPGGPPGV------PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPG 421
             PG++G  G KGE GP GPPG+      PGI G  G  G  G+ G+ G++G  GA G PG
Sbjct: 1094 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153

Query: 422  PTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG 481
            P GP G  G  G PG  G  G +G  G  G PG  G +GP+G  G QGP G +G  G  G
Sbjct: 1154 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1213

Query: 482  LKGEP---GLPGPPGE-------------GRAGEPGTAGPTGPPGVPGSPGITGPPGP-- 523
             KGEP   G PGPPGE             G AG PG AGP G  G PG  G  G PGP  
Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1273

Query: 524  -PGPPGPPGAPGAFDETGIAG 543
             PG PGPPG PG   + G+ G
Sbjct: 1274 FPGDPGPPGEPGPAGQDGVGG 1294



 Score =  375 bits (962), Expect = e-103
 Identities = 248/604 (41%), Positives = 280/604 (46%), Gaps = 135/604 (22%)

Query: 69  PLLPMDLKGEPGPPGKP-------GPRGPPGPPGFPGKPGMGKPGL--HGQPGPAGPPGF 119
           P  P + +  PG P +           G  G  G  G+P + +PG+   G PGPAGP G 
Sbjct: 354 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413

Query: 120 SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGA-- 177
                 GPPGL G  GPPG PG RG            PPG PGLPG  G  +PG PG   
Sbjct: 414 M-----GPPGLQGPTGPPGDPGDRG------------PPGRPGLPGADG--LPGPPGTML 454

Query: 178 ----------------------------------QGVPGPPGFQGEPGP----------- 192
                                             +G PGP G  G PGP           
Sbjct: 455 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 514

Query: 193 -QGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD 250
             G+PGP G RG++G  G  G+PG  G PG  G  G PG PG    G  G DGLPG PGD
Sbjct: 515 ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG--AKGDRGFDGLPGLPGD 572

Query: 251 K---GESGPPGVPGP------RGEPGAVGPKGPPGVDGV-------GVPGAAGLP----- 289
           K   GE GP G PGP      RGE G +GP+G PG  G        G PGA G P     
Sbjct: 573 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 632

Query: 290 ----------GPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGD 338
                     GPQG  G  G+ G  GP GL GP G  G PG  GP+G  G AG+PG  G 
Sbjct: 633 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 692

Query: 339 RGEPGEDGEPGEQ---GPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGD 395
            G PG++G+ GE+   GP G  GP G PG  G+ G  G  G KG  G  G  G PG +GD
Sbjct: 693 PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 752

Query: 396 QGPSGLAGKPGVPGERGLPGAHGP---------PGPTGPKGEPGFTGRPGGPGVAGALGQ 446
            G  G  G+ G  G RG  G  GP         PGP+G  GE G  G PG PG  G  G 
Sbjct: 753 MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP 812

Query: 447 KGDLGLPGQP------GLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP----GEGR 496
           KG  G PG P      G RG +G PG +G  GP GP+G  G +G  G PGP     G+G 
Sbjct: 813 KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872

Query: 497 AGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVL 556
            G PG  GP GP G  G PG  GPPGPPG  G PG PG   ETG  G   P G   G V+
Sbjct: 873 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG--PGGVV 930

Query: 557 GKGG 560
           G  G
Sbjct: 931 GPQG 934



 Score =  261 bits (666), Expect = 2e-69
 Identities = 166/405 (40%), Positives = 195/405 (48%), Gaps = 46/405 (11%)

Query: 190 PGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPG 249
           P  +  PG P +  +   +  G     GA G+ G  G P +  P  L    ++G PG  G
Sbjct: 358 PNEEFGPGVPAETDITETSINGH----GAYGEKGQKGEPAVVEPGML----VEGPPGPAG 409

Query: 250 DKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPS----GAKGEPGTRG 305
             G  GPPG+ GP G PG  G +GPPG  G+  PGA GLPGP G         G  G++G
Sbjct: 410 PAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL--PGADGLPGPPGTMLMLPFRYGGDGSKG 467

Query: 306 PP---------GLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL 356
           P           ++      + G PGP G  G  G  G  G  G  GE G+PG QGP+G+
Sbjct: 468 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 527

Query: 357 GGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA 416
            GPPG     G PG+RG PG  G  G  G PG  G RG  G  GL G  G  GERG  G 
Sbjct: 528 QGPPG---PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGP 584

Query: 417 HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGP 476
            GPPG  G +GE G  G  G PG AG  G  G  G PG PG  G +G+ G  GP G +GP
Sbjct: 585 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 644

Query: 477 QGLPGLKGEPGLPGPPG----EGRAGEPGTAGPTGPPGVPGSPGITGPPGPP-------- 524
           QG PG  G+ G PGP G    +G  G PG  GP G PG+ G PG  GPPG P        
Sbjct: 645 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 704

Query: 525 ----GPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFG 565
               GPPGP G  G     G+ G      GV G    KG K + G
Sbjct: 705 KGALGPPGPQGPIGYPGPRGVKGA----DGVRGLKGSKGEKGEDG 745



 Score =  229 bits (585), Expect = 5e-60
 Identities = 159/398 (39%), Positives = 182/398 (45%), Gaps = 95/398 (23%)

Query: 23   GPRASSG----GGAGGAAGYAPVKYIQPMQKGPVG------PPFREGKGQYLEMPLPLLP 72
            GPR   G     G  GA G+       P   GP+G      PP  +G+   +    P  P
Sbjct: 1132 GPRGQQGMFGQKGDEGARGF-------PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1184

Query: 73   MDLKGEPGPPGKPGPRGPPGP------------------PGFPGKPGMGKP-------GL 107
               +G  GP G  GP+GPPG                   PG PG+ G+G P       G 
Sbjct: 1185 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1244

Query: 108  HGQPGPAGPPGFSR-------MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160
             G PG AGPPG           G  GP G PG  GPPG+PG  G+ G+ GD+G  G PG 
Sbjct: 1245 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304

Query: 161  PGLPGPSGIT-IPGKPGAQGVPG---------------------PPGFQGEPGPQGEPGP 198
            PG PGPSG    PG PG +G PG                     PPG  G  GPQG  G 
Sbjct: 1305 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGK 1364

Query: 199  PGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGL----------GKPGLDGLPGA 247
            PG  GL+G  G VG+ GLPGA GQ G PGP G PG  GL          G PGL GL G 
Sbjct: 1365 PGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1424

Query: 248  PGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGLPGPQGPSGAKGE------ 300
            PG++GE G  G+PG +G PGA G  G PG  G +G PG  GLPGPQGP G KG       
Sbjct: 1425 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1484

Query: 301  ------PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGV 332
                  PG  G PG  G     +P L   K  R   G+
Sbjct: 1485 KGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGM 1522


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  441 bits (1134), Expect = e-123
 Identities = 284/644 (44%), Positives = 326/644 (50%), Gaps = 142/644 (22%)

Query: 23   GPRASSGG-------GAGGAAG-YAPVKYIQPMQKGPVGPPFREG----KGQYLEMPL-- 68
            GP+ +SGG       G  G  G   PV +  P  KGP GPP ++G     GQ  E     
Sbjct: 901  GPKGTSGGDGPPGPPGERGPQGPQGPVGF--PGPKGPPGPPGKDGLPGHPGQRGETGFQG 958

Query: 69   ---PLLPMDLKGEPGPPGKPGP---RGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSR 121
               P  P  + G  GP G+ GP   RG PGPPG PG+ G+ G  G  G  G  GP G S 
Sbjct: 959  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS- 1017

Query: 122  MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG-------ITIPGK 174
             GK GP GL G  G  G PG +G PG++G +G +GPPGP G PG  G       I +PG+
Sbjct: 1018 -GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1076

Query: 175  PGAQGVPGPPGFQGEPG---------------PQGEPGPPGDRGLKGDNG----VGQPGL 215
            PG QG PGP G +G PG               P G PGP G  G  G++G    +G+PG 
Sbjct: 1077 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1136

Query: 216  PGAPG---QGGAPGPPGLPGPAGL-------GKPG------------------------- 240
             G+ G   + G PGPPGL GP G        G+PG                         
Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1196

Query: 241  --LDGLPGAPGDKGESG------PPGVPGPRGEPG---AVGPKGPPG----VDGVGV--- 282
              L GLPG PG+KGE+G      PPG PGPRG  G   A GP+GPPG    V GVG    
Sbjct: 1197 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1256

Query: 283  PGAAGLPGPQG------------------PSGAKGEPGTRGPPGLIGPTG----YGMPGL 320
            PG AG PGP G                  P GA G PG +GPPG  GP G     G PG 
Sbjct: 1257 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1316

Query: 321  PGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPG------RRGP 374
            PGP G+ GPAG  G+ GD+GE G+ G+PG  GP G  GPPG PG  G PG      R+G 
Sbjct: 1317 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1376

Query: 375  PGPKGEAGPGGPPGVPGIRGDQGPS------GLAGKPGVPGERGLPGA---HGPPGPTGP 425
             G KGEAG  GPPG  G  G QGP+      GL G PG  GE+GLPGA    GPPGP GP
Sbjct: 1377 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1436

Query: 426  KGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGE 485
             G PG  G PG  G  G  G  G +G PG+ G +G  G+PG QG  G  G  G+PG  G 
Sbjct: 1437 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1496

Query: 486  PGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPG 528
             G PGPPG  G  G  G  G TGP G  G  G+ GPPG PGPPG
Sbjct: 1497 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  433 bits (1114), Expect = e-121
 Identities = 274/603 (45%), Positives = 303/603 (50%), Gaps = 66/603 (10%)

Query: 24   PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPG 83
            P A+   GA G AG    +     Q+GP GP    G       P P       G PGPPG
Sbjct: 861  PGANGEKGARGVAGKPGPRG----QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG 916

Query: 84   KPGPRGPPGPPGFPGKPGM----GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGP--- 136
            + GP+GP GP GFPG  G     GK GL G PG  G  GF   GK GPPG  G VGP   
Sbjct: 917  ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ--GKTGPPGPGGVVGPQGP 974

Query: 137  ---------------PGQPGLRGEPGIRGDQGLRGPPGPPGLPG---PSGIT-IPGKPGA 177
                           PG PG +G PG  G +G +G PGP G+ G   P+G+   PG+ G 
Sbjct: 975  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034

Query: 178  QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQP-GLPGAPGQGGAPGPPG------- 229
             G  G PG +G  GPQG PGP G  G +G  G   P GLPG PG  G PGP G       
Sbjct: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094

Query: 230  -----------LPGPAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGV 277
                       + GP GL G  G  G PG  GDKGE G PG  G +G+ G  GP GPPG+
Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154

Query: 278  DG-VGVPGAAG---LPGP---QGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKG---D 326
             G VG PG AG    PGP   QG  G KG+ G RG PG  GP G  G+PG PG KG   D
Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1214

Query: 327  RGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGP 386
             GP G PG  G RG  G +G  G QGP G  G  G  G  G PG  G PGP GEAG GGP
Sbjct: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1274

Query: 387  PGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQ 446
             G  G +G+ GP G AG PG  G  G  G  G PGP G  G+PG  G PG  G  G  G 
Sbjct: 1275 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1334

Query: 447  KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTAGP 505
            KG+ G PGQPG  GPSG  G  GP G  GP G  G +G  G  G  GE G  G PG  GP
Sbjct: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394

Query: 506  TGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKPQ 563
             GP G  G PG  G  G PGP G  G PGA  + G  G   P G  G++G    KG K  
Sbjct: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1454

Query: 564  FGL 566
             GL
Sbjct: 1455 PGL 1457



 Score =  422 bits (1085), Expect = e-118
 Identities = 264/605 (43%), Positives = 305/605 (50%), Gaps = 99/605 (16%)

Query: 48   QKGPVGPPFREGKGQYLEMPLP-------LLPMDLKGEPGPPGKPGPRGPPGPPGFPGKP 100
            +KG  G P     G  +E P         + P  L+G  GPPG PG RGPPG PG PG  
Sbjct: 424  EKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGAD 483

Query: 101  GM-GKPGL-------HGQPGPAGPP------------GFSRMGKAGPP------GLPGKV 134
            G+ G PG        +G  G  GP               +R+   GPP      G PG V
Sbjct: 484  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 543

Query: 135  GPPGQPGLRGE---PGIRGDQGLRGPPGPPGLPG-------PSGITIPGKPGAQ------ 178
            G PG  G +GE   PG +G +G++GPPGP G PG         G  +PG+PGA+      
Sbjct: 544  GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 603

Query: 179  ---GVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPA 234
               G+PG  G +GE GPQG PGPPGD G++G++G +G  GLPG  G  G  GP G PG  
Sbjct: 604  GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 663

Query: 235  GLGKPGLDGLPGAPGDK------GESGPPGV---PGPRGEPGAVGPKGPPGVDG-VGVPG 284
              G+PG+ G+ G PG K      GE GPPG    PGP+G PG  GP GPPG  G  G PG
Sbjct: 664  --GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG 721

Query: 285  AAGLPGPQGP------SGAKGEPGTRGPPGLIGPTGY----------GMPGLPGPKGDRG 328
             AGLPG  GP       G  GE G  GPPG  GP GY          G+ GL G KG++G
Sbjct: 722  LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 781

Query: 329  PAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPG 388
              G PG  GD G  G+ GE G+ GP+G  GP G  G AG  G  GP G  GE G  G PG
Sbjct: 782  EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 841

Query: 389  VPGIRGDQGPSGLAGKPGVPGER---------GLPGAHGPPGPTGPKGEPGFTGRPGGPG 439
            +PG  G QGP G  G PG PG           G PG  G  GPTGP+G  G  G  G PG
Sbjct: 842  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 901

Query: 440  VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAG 498
              G  G  G  G PG+ G +GP G  G  GP GP GP G  GL G PG  G  G +G+ G
Sbjct: 902  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961

Query: 499  EP---GTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAV 555
             P   G  GP GP G  G  G  G PGPPGPPG  G PGA  + G  G   P G     +
Sbjct: 962  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG-----I 1016

Query: 556  LGKGG 560
             GK G
Sbjct: 1017 SGKDG 1021



 Score =  417 bits (1073), Expect = e-116
 Identities = 262/591 (44%), Positives = 291/591 (49%), Gaps = 87/591 (14%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPG---FPGKPGM-GKP 105
            GPVG P   G       P P  P  ++G PGP GKPG RG PG  G    PG+PG  G  
Sbjct: 541  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 600

Query: 106  GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG 165
            G  G PG  G  G    G+ GP G PG   PPG  G+RGE G  G +GL G  GP GL G
Sbjct: 601  GFDGLPGLPGDKG--HRGERGPQGPPG---PPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 655

Query: 166  PSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGA 224
            P G    PG+PG  GV GPPG +G  GPQGEPGPPG +G  G  G+  PG  G  G  G 
Sbjct: 656  PRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGE 713

Query: 225  PGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGV---PGPRGEPGAVGPKGPPGVDGV- 280
             GP G PG AGL  PG DG PG PG +G+SG  G    PGP+G  G  GP+G  G DGV 
Sbjct: 714  KGPQGKPGLAGL--PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR 771

Query: 281  ------GVPGAAGLPGPQGPSGAKG------------EPGTRGPPGLIGPTGY------- 315
                  G  G  G PG +G  G KG            E G  GP G  GPTG        
Sbjct: 772  GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQA 831

Query: 316  ---------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSA 366
                     G+PG PG +G +G  G PG  G  GE G  G  G+ GP+G  GP G  GS 
Sbjct: 832  GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 891

Query: 367  GLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPK 426
            G  G  G PGPKG +G  GPPG PG RG QGP G  G PG  G  G PG  G PG  G +
Sbjct: 892  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 951

Query: 427  GEPGFTGRPGGPGVAGALGQK---------------------GDLGLPGQPGLRGPSGIP 465
            GE GF G+ G PG  G +G +                     G+ GLPG  G  G  G P
Sbjct: 952  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011

Query: 466  GLQGPAGPIGPQGLPGLKGEPGLPGPPG----EGRAGEPGTAGPTGPPGVPGSPGITGPP 521
            G QG +G  GP GL G  GE GLPG  G    +G  G  G  GP G PG  GS G  GP 
Sbjct: 1012 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1071

Query: 522  GPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGAV-----LGKGGKP 562
            G PG PGP G PG   E G  G   P G     GV+G V      G  G P
Sbjct: 1072 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1122



 Score =  402 bits (1034), Expect = e-112
 Identities = 270/681 (39%), Positives = 313/681 (45%), Gaps = 162/681 (23%)

Query: 23   GPRASSGG-GAGGAAGY----APVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKG 77
            GPR + G  G  G AG      P   + P  +G  GPP ++G      +P P  P+   G
Sbjct: 655  GPRGTPGAPGQPGMAGVDGPPGPKGNMGP--QGEPGPPGQQGNPGPQGLPGPQGPIGPPG 712

Query: 78   EPGPPGKPG---------P------------------RGPPGPPGFPGKPGM-------G 103
            E GP GKPG         P                   GP GP G+PG  G+       G
Sbjct: 713  EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 772

Query: 104  KPGLHGQPGPAGPPGF----------------SRMGKAGPPGLPGKVGPPGQPGLRGEPG 147
              G  G+ G  G PGF                   G+ GP G  G+ GP G PG  G+ G
Sbjct: 773  LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 832

Query: 148  IRGDQGLRGPPGPPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKG 206
             +G  G+ G PG PG  GP G T  PG PGA G  G  G  G+PGP+G+ GP G RG +G
Sbjct: 833  EKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 892

Query: 207  DNG-VGQPGLPGAPGQGGAPGPP------------GLPGPAG-LGKPGLDGLPGAPGDKG 252
              G  G+PG  G  G  G PGPP            G PGP G  G PG DGLPG PG +G
Sbjct: 893  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 952

Query: 253  ES---------------------------------GPPGVPGPRGEPGAV---GPKGPPG 276
            E+                                 GPPG PG +G PGA    G KG PG
Sbjct: 953  ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1012

Query: 277  VDGV----------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG----------YG 316
              G+          G PG  GLPG QG  G KG  G +GPPG +G  G           G
Sbjct: 1013 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1072

Query: 317  MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS---------AG 367
            +PG PGP+G  GPAG  G  G++G  G  G  G QGP GL GP G  GS          G
Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1132

Query: 368  LPGRRGPPGPKGEAGPGGPPGV------PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPG 421
             PG++G  G KGE GP GPPG+      PGI G  G  G  G+ G+ G++G  GA G PG
Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192

Query: 422  PTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG 481
            P GP G  G  G PG  G  G +G  G  G PG  G +GP+G  G QGP G +G  G  G
Sbjct: 1193 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1252

Query: 482  LKGEP---GLPGPPGE-------------GRAGEPGTAGPTGPPGVPGSPGITGPPGP-- 523
             KGEP   G PGPPGE             G AG PG AGP G  G PG  G  G PGP  
Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1312

Query: 524  -PGPPGPPGAPGAFDETGIAG 543
             PG PGPPG PG   + G+ G
Sbjct: 1313 FPGDPGPPGEPGPAGQDGVGG 1333



 Score =  375 bits (962), Expect = e-103
 Identities = 248/604 (41%), Positives = 280/604 (46%), Gaps = 135/604 (22%)

Query: 69  PLLPMDLKGEPGPPGKP-------GPRGPPGPPGFPGKPGMGKPGL--HGQPGPAGPPGF 119
           P  P + +  PG P +           G  G  G  G+P + +PG+   G PGPAGP G 
Sbjct: 393 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452

Query: 120 SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGA-- 177
                 GPPGL G  GPPG PG RG            PPG PGLPG  G  +PG PG   
Sbjct: 453 M-----GPPGLQGPTGPPGDPGDRG------------PPGRPGLPGADG--LPGPPGTML 493

Query: 178 ----------------------------------QGVPGPPGFQGEPGP----------- 192
                                             +G PGP G  G PGP           
Sbjct: 494 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 553

Query: 193 -QGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD 250
             G+PGP G RG++G  G  G+PG  G PG  G  G PG PG    G  G DGLPG PGD
Sbjct: 554 ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG--AKGDRGFDGLPGLPGD 611

Query: 251 K---GESGPPGVPGP------RGEPGAVGPKGPPGVDGV-------GVPGAAGLP----- 289
           K   GE GP G PGP      RGE G +GP+G PG  G        G PGA G P     
Sbjct: 612 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 671

Query: 290 ----------GPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGD 338
                     GPQG  G  G+ G  GP GL GP G  G PG  GP+G  G AG+PG  G 
Sbjct: 672 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 731

Query: 339 RGEPGEDGEPGEQ---GPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGD 395
            G PG++G+ GE+   GP G  GP G PG  G+ G  G  G KG  G  G  G PG +GD
Sbjct: 732 PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 791

Query: 396 QGPSGLAGKPGVPGERGLPGAHGP---------PGPTGPKGEPGFTGRPGGPGVAGALGQ 446
            G  G  G+ G  G RG  G  GP         PGP+G  GE G  G PG PG  G  G 
Sbjct: 792 MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP 851

Query: 447 KGDLGLPGQP------GLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP----GEGR 496
           KG  G PG P      G RG +G PG +G  GP GP+G  G +G  G PGP     G+G 
Sbjct: 852 KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911

Query: 497 AGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVL 556
            G PG  GP GP G  G PG  GPPGPPG  G PG PG   ETG  G   P G   G V+
Sbjct: 912 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG--PGGVV 969

Query: 557 GKGG 560
           G  G
Sbjct: 970 GPQG 973



 Score =  261 bits (666), Expect = 2e-69
 Identities = 166/405 (40%), Positives = 195/405 (48%), Gaps = 46/405 (11%)

Query: 190 PGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPG 249
           P  +  PG P +  +   +  G     GA G+ G  G P +  P  L    ++G PG  G
Sbjct: 397 PNEEFGPGVPAETDITETSINGH----GAYGEKGQKGEPAVVEPGML----VEGPPGPAG 448

Query: 250 DKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPS----GAKGEPGTRG 305
             G  GPPG+ GP G PG  G +GPPG  G+  PGA GLPGP G         G  G++G
Sbjct: 449 PAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL--PGADGLPGPPGTMLMLPFRYGGDGSKG 506

Query: 306 PP---------GLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL 356
           P           ++      + G PGP G  G  G  G  G  G  GE G+PG QGP+G+
Sbjct: 507 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 566

Query: 357 GGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA 416
            GPPG     G PG+RG PG  G  G  G PG  G RG  G  GL G  G  GERG  G 
Sbjct: 567 QGPPG---PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGP 623

Query: 417 HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGP 476
            GPPG  G +GE G  G  G PG AG  G  G  G PG PG  G +G+ G  GP G +GP
Sbjct: 624 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 683

Query: 477 QGLPGLKGEPGLPGPPG----EGRAGEPGTAGPTGPPGVPGSPGITGPPGPP-------- 524
           QG PG  G+ G PGP G    +G  G PG  GP G PG+ G PG  GPPG P        
Sbjct: 684 QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 743

Query: 525 ----GPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFG 565
               GPPGP G  G     G+ G      GV G    KG K + G
Sbjct: 744 KGALGPPGPQGPIGYPGPRGVKGA----DGVRGLKGSKGEKGEDG 784



 Score =  229 bits (585), Expect = 5e-60
 Identities = 159/398 (39%), Positives = 182/398 (45%), Gaps = 95/398 (23%)

Query: 23   GPRASSG----GGAGGAAGYAPVKYIQPMQKGPVG------PPFREGKGQYLEMPLPLLP 72
            GPR   G     G  GA G+       P   GP+G      PP  +G+   +    P  P
Sbjct: 1171 GPRGQQGMFGQKGDEGARGF-------PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1223

Query: 73   MDLKGEPGPPGKPGPRGPPGP------------------PGFPGKPGMGKP-------GL 107
               +G  GP G  GP+GPPG                   PG PG+ G+G P       G 
Sbjct: 1224 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1283

Query: 108  HGQPGPAGPPGFSR-------MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160
             G PG AGPPG           G  GP G PG  GPPG+PG  G+ G+ GD+G  G PG 
Sbjct: 1284 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343

Query: 161  PGLPGPSGIT-IPGKPGAQGVPG---------------------PPGFQGEPGPQGEPGP 198
            PG PGPSG    PG PG +G PG                     PPG  G  GPQG  G 
Sbjct: 1344 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGK 1403

Query: 199  PGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGL----------GKPGLDGLPGA 247
            PG  GL+G  G VG+ GLPGA GQ G PGP G PG  GL          G PGL GL G 
Sbjct: 1404 PGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1463

Query: 248  PGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGLPGPQGPSGAKGE------ 300
            PG++GE G  G+PG +G PGA G  G PG  G +G PG  GLPGPQGP G KG       
Sbjct: 1464 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1523

Query: 301  ------PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGV 332
                  PG  G PG  G     +P L   K  R   G+
Sbjct: 1524 KGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGM 1561


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  437 bits (1125), Expect = e-122
 Identities = 263/593 (44%), Positives = 308/593 (51%), Gaps = 73/593 (12%)

Query: 21  GCGPRASSGGGAG--GAAGYAPVKYIQPMQ--KGPVGPPFREGKGQYLEMPLPLLPMDLK 76
           G   R    G AG  GA G+  V+  +  Q  KG +G P  +G         P  P  L 
Sbjct: 274 GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLP 333

Query: 77  G-------EPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSRM------ 122
           G        P  PG+ GP+G  G PG PG+PG+ G+PG  G  GP GPPG          
Sbjct: 334 GTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGA 393

Query: 123 -GKAGPPGLPGKVGPPGQ---------PGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIP 172
            G AG PG PG VG PG          PGLRG PG  G++G +G  G  G PGP G    
Sbjct: 394 PGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR-- 451

Query: 173 GKPGAQGVPGPPGF--QGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPG---- 226
           G PGA G+PGPPG    GEPG +G PG PG  G KGD G   PG+PG+PG  G PG    
Sbjct: 452 GDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGA--PGIPGSPGSRGDPGIGVA 509

Query: 227 -PPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVG----------PKGP 274
            PPG  GP G  G PG  GLPG PG +G +G  G+      PG +           P GP
Sbjct: 510 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLS-PGDINLLAKDVCNDCPPGP 568

Query: 275 PGVDGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVP 333
           PG+ G+ G  G  G+PG  G  G +G+ G  GPPGL GP     PG+ GP+G +G  G  
Sbjct: 569 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP-----PGIAGPQGSQGERGAD 623

Query: 334 GLLGDRGEPGEDGEPGEQGPQGLGGPPG---LPGSAGLPGRRGPPGPKGEAGPGGPPGVP 390
           G +G +G+ G  G PG  GP G  GPPG   + G+AG PG +G PG +G  GP GP G+P
Sbjct: 624 GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP 683

Query: 391 GIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDL 450
           GI G++G  G  GKPG PGE G  G  G PGP G +G PGF G  G  G  G  G+ G +
Sbjct: 684 GIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAM 743

Query: 451 GLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-------------EGRA 497
           GLPGQ GL G  G  G  GP GP GP+G PG  G PG PG PG              G  
Sbjct: 744 GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP 803

Query: 498 GEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGG 550
           G PG  GP GPPG PG  G+ G  G PG PG PG  G   + GI G   P GG
Sbjct: 804 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG 856



 Score =  416 bits (1070), Expect = e-116
 Identities = 267/650 (41%), Positives = 308/650 (47%), Gaps = 121/650 (18%)

Query: 23   GPRASSGG-GAGGAAGY--APVKYIQPMQKGPVG----PPFREGKGQYLEMPLPLLPMDL 75
            G +   G  GA GAAG   AP     P   GP G    P  R   G+  E          
Sbjct: 383  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERG----EKGA 438

Query: 76   KGEPGPPGKPGPRGPPGPPGFPGKPGMGK---PGLHGQPGPAGPPGFSRMGKAGPPGLPG 132
             GE G PG  GPRG PG PG PG PG GK   PGL G PG  GP G    G  G PG+PG
Sbjct: 439  AGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK--GDRGAPGIPG 496

Query: 133  KVG--------------PPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGK---- 174
              G              P G PG +G PG RG  G  GP GP G  G S +  PG     
Sbjct: 497  SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLL 556

Query: 175  ---------PGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPG----- 220
                     PG  G+PG PGF+G+ G  G+PG  G  G KG+   G PGLPG PG     
Sbjct: 557  AKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGE--AGPPGLPGPPGIAGPQ 614

Query: 221  -------------QGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPG 267
                         Q G  G PG+PG   +G PG  G PGA G  G +GPPG+ G  G+ G
Sbjct: 615  GSQGERGADGEVGQKGDQGHPGVPG--FMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEG 672

Query: 268  AVGPKGPPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY----GMPG 319
              GP+GP G+ G+    G  G  G PGP G  G  GEPG  GP G  GP G+    G  G
Sbjct: 673  PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSG 732

Query: 320  LPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGP---PG 376
             PGP+G+ G  G+PG  G  G+ G+ G  G QGPQG  GPPG  GS G PG  GP   PG
Sbjct: 733  APGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPG 792

Query: 377  PKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPG 436
             KG  G  G PG+PG  G +GP G  G+ GVPG+ G+PG  G PG  G +G+PG  G  G
Sbjct: 793  QKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKG 852

Query: 437  GPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGP---QGLPGLKGE-------- 485
             PG  G  G  G  G  G  GL GP G+PG  GP GP GP    G PGL+GE        
Sbjct: 853  PPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLR 912

Query: 486  ------------------------------PGLPGPPG-EGRAGEPGTAGPTGPPGVPGS 514
                                           G PGPPG  G+ G PG AGP G PG PG 
Sbjct: 913  RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ 972

Query: 515  PGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQF 564
             G+ GP GP GP G  GA G   + G  G+ L        + G+ G+P +
Sbjct: 973  GGLEGPSGPIGPKGERGAKG---DPGAPGVGLRGEMGPPGIPGQPGEPGY 1019



 Score =  317 bits (812), Expect = 2e-86
 Identities = 206/493 (41%), Positives = 231/493 (46%), Gaps = 99/493 (20%)

Query: 177 AQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAG 235
           A+  PG     GEPG +GE G PG  GL+G+ G  G  G PG  G+ G PG PG PG  G
Sbjct: 239 AKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 298

Query: 236 ----------LGKPGLDGLPGAPGDKGESGPPGVPG--------PR--GEPGAVGPKGPP 275
                     LG PGL G  G  G+ G +GPPG+PG        PR  GE G  G KG P
Sbjct: 299 EKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDP 358

Query: 276 GVDG----VGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIG-PTGYGMPGLPGPKGDRGPA 330
           G+ G     G PG  G  GP GP GAKG+ G  G PG  G P   G  G PGP G  G  
Sbjct: 359 GLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSV 418

Query: 331 GVPGL---------LGDRGEPGEDGEPGEQGPQGLGGPPGLPGS-----------AGLPG 370
           G PGL          G++G  GE+G PG  GP+G  G PGLPG             G PG
Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG 478

Query: 371 RRGPPGPKGEAGPGGPPGVPGIRGD--------QGPSGLAGKPGVPGERGLPGAHGPPGP 422
             GP G KG+ G  G PG PG RGD         GPSG  G  G PG RGLPG  GP GP
Sbjct: 479 LPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 538

Query: 423 TGP------------------------------------KGEPGFTGRPGGPGVAGALGQ 446
            G                                     KG+ G  G+PG  G  G  G+
Sbjct: 539 AGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGE 598

Query: 447 KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTAGP 505
            G  GLPG PG+ GP G  G +G  G +G +G  G  G PG  GPPG  G  G  G AG 
Sbjct: 599 AGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGA 658

Query: 506 TGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFG 565
            GPPG+ GSPG  GPPGP GP G PG PG   + G  G   P G       GK G+P  G
Sbjct: 659 AGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEP-----GKAGEP--G 711

Query: 566 L-GELSAHATPAF 577
           L G   A   P F
Sbjct: 712 LPGPEGARGPPGF 724



 Score =  236 bits (601), Expect = 7e-62
 Identities = 159/390 (40%), Positives = 197/390 (50%), Gaps = 45/390 (11%)

Query: 191 GPQGEPGPPGDRGLKGDNGVGQPG-LPGAPG-QGGAPGPPGLPGPAGLGKPGLDGLPGAP 248
           GP+ +P    D+G +G  G G    LP +   Q   P   G    A LG  G       P
Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQG-------P 224

Query: 249 GD-KGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGTRGP 306
            D + ++    +   +  PG     G PG  G  G+PG  GL G  G  G  G PG +G 
Sbjct: 225 ADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGE 284

Query: 307 PGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS 365
            GL G  G+ G+ G  G +G++G  G+PGL GDRGE GE G           GPPGLPG+
Sbjct: 285 AGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGP---------AGPPGLPGT 335

Query: 366 AGL----PGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPG 421
             L    P   G  GPKGE G  G PG PG++G  G  G  G  G PG +G  GAHG PG
Sbjct: 336 TSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG 395

Query: 422 PTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG 481
             G  G PG  G PG  G  G++G  G  G PG+ G RG  G  G +G  GP+GP+G PG
Sbjct: 396 AAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 455

Query: 482 LKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGP---PGPPGPPGPPGAPGAFDE 538
               PGLPGPPG+G+ GEPG         + GSPG+ GP    G  G PG PG+PG+  +
Sbjct: 456 A---PGLPGPPGKGKDGEPG---------LRGSPGLPGPLGTKGDRGAPGIPGSPGSRGD 503

Query: 539 TGI--AGLHLPNG--GVEGAVLGKGGKPQF 564
            GI  AG   P+G  G +G+  G  G P F
Sbjct: 504 PGIGVAGPPGPSGPPGDKGSP-GSRGLPGF 532



 Score =  183 bits (465), Expect = 4e-46
 Identities = 121/306 (39%), Positives = 143/306 (46%), Gaps = 73/306 (23%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREG-KGQYLEMPLPLLPMDLKGEPG 80
            GP+   G  G  G+ G        P + GP G P ++G KG+     LP       G  G
Sbjct: 765  GPQGPRGPPGKNGSPG-------SPGEPGPSGTPGQKGSKGENGSPGLP----GFLGPRG 813

Query: 81   PPGKPGPRGPPGPPGFPGKPG----------------MGKPGLHGQPGPAGPPGFS-RMG 123
            PPG+PG +G PG  G PGKPG                 G PG  GQPG  G PG     G
Sbjct: 814  PPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTG 873

Query: 124  KAGPPGLPGK---VGPPGQPGLRGEPGIRGD----------------------------- 151
              GP GLPG+   VGPPG PG  G PG+RG+                             
Sbjct: 874  LMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQ 933

Query: 152  ------QGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLK 205
                  +  +G PGPPG PG  G+  PG+ G  G PG PG  G  GP G  GP G+RG K
Sbjct: 934  MPPAYMKSSQGRPGPPGPPGKDGL--PGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAK 991

Query: 206  GDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGE 265
            GD G   PG+ G  G+ G PG PG PG  G  K GL G+PG  G+ G +G PG+PGP G 
Sbjct: 992  GDPGA--PGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGP 1048

Query: 266  PGAVGP 271
            PG   P
Sbjct: 1049 PGQCDP 1054



 Score =  170 bits (430), Expect = 5e-42
 Identities = 113/277 (40%), Positives = 135/277 (48%), Gaps = 50/277 (18%)

Query: 335 LLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS----AGLP-----------GRRGP----- 374
           LLG R +P E+ + G QG  G G    LP S      +P           G +GP     
Sbjct: 170 LLGPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRA 229

Query: 375 -------------PGPK------GEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPG 415
                        PG K      GE G  G PG PG+RG+ G  GLAG+PG  GE GLPG
Sbjct: 230 DARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPG 289

Query: 416 AHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI----PGLQGPA 471
           A G PG  G KG+ G  G  G PG+ G  G+KG+ G  G PGL G + +    P + G  
Sbjct: 290 APGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQ 349

Query: 472 GPIGPQGLPGLKGEPGLPGPPGE----GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPP 527
           GP G +G PGL GEPGL G PGE    G  G PG  G  G  G PG+ G  G PG  G P
Sbjct: 350 GPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP 409

Query: 528 GPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKP 562
           GP G PG+    G+ G    +G  G +GA  G+ G P
Sbjct: 410 GPSGPPGSVGAPGLRGTPGKDGERGEKGAA-GEEGSP 445


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  435 bits (1118), Expect = e-122
 Identities = 269/627 (42%), Positives = 313/627 (49%), Gaps = 106/627 (16%)

Query: 21   GCGPRASSGGGAG--GAAGYAPVKYIQPMQ--KGPVGPPFREGKGQYLEMPLPLLPMDLK 76
            G   R    G AG  GA G+  V+  +  Q  KG +G P  +G         P  P  L 
Sbjct: 792  GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLP 851

Query: 77   G-------EPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFSRM------ 122
            G        P  PG+ GP+G  G PG PG+PG+ G+PG  G  GP GPPG          
Sbjct: 852  GTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGA 911

Query: 123  -GKAGPPGLPGKVGPPGQ---------PGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIP 172
             G AG PG PG VG PG          PGLRG PG  G++G +G  G  G PGP G    
Sbjct: 912  PGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR-- 969

Query: 173  GKPGAQGVPGPPGF--QGEPGPQGEPGPPGDRG--------------------LKGDNGV 210
            G PGA G+PGPPG    GEPG +G PG PG  G                    +KGD G 
Sbjct: 970  GDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029

Query: 211  GQPGLPGAPGQGGAPG-----PPGLPGPAG-LGKPGLDGLPGAPGDKGESG---PPGVPG 261
              PG+PG+PG  G PG     PPG  GP G  G PG  GLPG PG +G +G    PG PG
Sbjct: 1030 --PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPG 1087

Query: 262  PRGEPGAVG---------------------PKGPPGVDGV-GVPGAAGLPGPQGPSGAKG 299
             RG PG  G                     P GPPG+ G+ G  G  G+PG  G  G +G
Sbjct: 1088 ERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG 1147

Query: 300  EPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGP 359
            + G  GPPGL GP     PG+ GP+G +G  G  G +G +G+ G  G PG  GP G  GP
Sbjct: 1148 KKGEAGPPGLPGP-----PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP 1202

Query: 360  PG---LPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA 416
            PG   + G+AG PG +G PG +G  GP GP G+PGI G++G  G  GKPG PGE G  G 
Sbjct: 1203 PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGE 1262

Query: 417  HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGP 476
             G PGP G +G PGF G  G  G  G  G+ G +GLPGQ GL G  G  G  GP GP GP
Sbjct: 1263 PGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGP 1322

Query: 477  QGLPGLKGEPGLPGPPG-------------EGRAGEPGTAGPTGPPGVPGSPGITGPPGP 523
            +G PG  G PG PG PG              G  G PG  GP GPPG PG  G+ G  G 
Sbjct: 1323 RGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGV 1382

Query: 524  PGPPGPPGAPGAFDETGIAGLHLPNGG 550
            PG PG PG  G   + GI G   P GG
Sbjct: 1383 PGKPGEPGFKGERGDPGIKGDKGPPGG 1409



 Score =  432 bits (1110), Expect = e-121
 Identities = 269/614 (43%), Positives = 309/614 (50%), Gaps = 76/614 (12%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVG---PPFREGKGQYLEMPLPLLPMDLKGE 78
            GP  + G  G  G  G  P    +  +KG +G   PP R+G       P  L    L GE
Sbjct: 505  GPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGE 564

Query: 79   PGPPGKPGPRGPPGPPGFPGKPGM----GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKV 134
             G  G  GP G PGPPG  G PG+    G+ G  G+ G  G  GF        PG PG  
Sbjct: 565  VGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGF--------PGKPGDT 616

Query: 135  GPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG----PSGIT----IPGKPGAQGVPGPPGF 186
            G  G+PG  G  G +G++G  GP GPPG+PG      G+      PG  G QG PGPPG 
Sbjct: 617  GQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGA 676

Query: 187  QGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAG----LGKPGL 241
            +G  GP+G  GPPG +GL+G  G +G PG+PG  G  G PGPPG+PGP G     G PG 
Sbjct: 677  RGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGE 736

Query: 242  DGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGE 300
             G PG PG  G +GPPG  GP G PG  G KG PG  G  G+PG  GL G  G  G  G 
Sbjct: 737  IGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGR 796

Query: 301  PGTRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGE------------ 347
            PG +G  GL G  G+ G+ G  G +G++G  G+PGL GDRGE GE G             
Sbjct: 797  PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 856

Query: 348  -------PGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG 400
                   PGEQGP+G  G PGLPG  GL GR   PG  G  GP GPPG  G  G  G  G
Sbjct: 857  FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR---PGELGPQGPTGPPGAKGQEGAHGAPG 913

Query: 401  LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
             AG PG PG  G PG  GPPG     G PG  G PG  G  G  G  G+ G PG  G RG
Sbjct: 914  AAGNPGAPGHVGAPGPSGPPGSV---GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRG 970

Query: 461  PSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRA------------GEPGTAGPTGP 508
              G PGL GP G  G  G PGL+G PGLPGP G   A            G     G  G 
Sbjct: 971  DPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029

Query: 509  PGVPGSPGITGPP-----GPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGK 561
            PG+PGSPG  G P     GPPGP GPPG  G+    G+ G   P G  G +GA    G +
Sbjct: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGER 1089

Query: 562  PQFGLGELSAHATP 575
               G   LS+  +P
Sbjct: 1090 GPPGKPGLSSLLSP 1103



 Score =  415 bits (1067), Expect = e-116
 Identities = 278/681 (40%), Positives = 308/681 (45%), Gaps = 148/681 (21%)

Query: 23   GPRASSGG-GAGGAAGY--APVKYIQPMQKGPVG----PPFREGKGQYLEMPLPLLPMDL 75
            G +   G  GA GAAG   AP     P   GP G    P  R   G+  E          
Sbjct: 901  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERG----EKGA 956

Query: 76   KGEPGPPGKPGPRGPPGPPGFPGKPGMGK---PGLHGQPGPAGPPGFSRM---------- 122
             GE G PG  GPRG PG PG PG PG GK   PGL G PG  GP G              
Sbjct: 957  AGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC 1016

Query: 123  --------GKAGPPGLPGKVGPPGQPGL--------RGEPGIRGDQGLRGPPGPPGLPGP 166
                    G  G PG+PG  G  G PG+         G PG +G  G RG PG PG  GP
Sbjct: 1017 ALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 1076

Query: 167  SGIT-IPGKPGAQGVPGPPGFQG--EPG-------------PQGEPGPPGDRGLKGDNGV 210
            +G    PG PG +G PG PG      PG             P G PG PG  G KGD GV
Sbjct: 1077 AGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGV 1136

Query: 211  -GQPGLPGAPGQGGAPGPPGLPGPAGLGKP-------GLDGLPGAPGDKGESG------P 256
             G+PG  G  G+ G  GPPGLPGP G+  P       G DG  G  GD+G  G      P
Sbjct: 1137 PGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGP 1196

Query: 257  PGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-- 314
            PG PGP G  G  G  GPPG+ G   PG  G PGPQGPSG  G PG  G  G  G  G  
Sbjct: 1197 PGNPGPPGADGIAGAAGPPGIQGS--PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP 1254

Query: 315  -----YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGE------------------- 350
                  G PGLPGP+G RGP G  G  GD G PG  GE G                    
Sbjct: 1255 GEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPT 1314

Query: 351  --QGPQGLGGPPGLPGSAGLPGRRGP---PGPKGEAGPGGPPGVPGIRGDQGPSGLAGKP 405
              QGPQG  GPPG  GS G PG  GP   PG KG  G  G PG+PG  G +GP G  G+ 
Sbjct: 1315 GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEK 1374

Query: 406  GVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIP 465
            GVPG+ G+PG  G PG  G +G+PG  G  G PG  G  G  G  G  G  GL GP G+P
Sbjct: 1375 GVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP 1434

Query: 466  GLQGPAGPIGP---QGLPGLKGE------------------------------------- 485
            G  GP GP GP    G PGL+GE                                     
Sbjct: 1435 GENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKS 1494

Query: 486  -PGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAG 543
              G PGPPG  G+ G PG AGP G PG PG  G+ GP GP GP G  GA G   + G  G
Sbjct: 1495 SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG---DPGAPG 1551

Query: 544  LHLPNGGVEGAVLGKGGKPQF 564
            + L        + G+ G+P +
Sbjct: 1552 VGLRGEMGPPGIPGQPGEPGY 1572



 Score =  412 bits (1060), Expect = e-115
 Identities = 267/622 (42%), Positives = 303/622 (48%), Gaps = 112/622 (18%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            G R + G  G+ G+ G   +    P   GP GPP  +G      +P    P    G  G 
Sbjct: 1025 GDRGAPGIPGSPGSRGDPGIGVAGP--PGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGA 1082

Query: 82   PGKPGPRGPPGPPGF---------------------PGKPGM-GKPGLHGQPGPAGPPGF 119
            PG PG RGPPG PG                      PG PG+ G PG  G  G  G PG 
Sbjct: 1083 PGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 1142

Query: 120  S----RMGKAGPPGLPGK---VGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIP 172
                 + G+AGPPGLPG     GP G  G RG  G  G +G +G PG PG  GP G   P
Sbjct: 1143 EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN--P 1200

Query: 173  GKPGAQGVPG---PPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPG 229
            G PGA G+ G   PPG QG PG +G PGP G  GL G      PG  G  G+ G PGPPG
Sbjct: 1201 GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI-----PGEEGKEGRDGKPGPPG 1255

Query: 230  LPGPAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGL 288
             PG AG  G PG +G  G PG KG +G  G PGPRGE GA+G  G  G+ G    G  G 
Sbjct: 1256 EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD--GDTGP 1313

Query: 289  PGPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGE 347
             GPQGP G +G PG  G PG  G  G  G PG  G KG+ G  G+PG LG RG PGE   
Sbjct: 1314 TGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE--- 1370

Query: 348  PGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGV 407
            PGE+G  G  G PG PG  G  G RG PG KG+ GP G  G PG   D G  G  G  G+
Sbjct: 1371 PGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG---DPGIPGHKGHTGL 1427

Query: 408  PGERGLPGAHGPPGPTGPKGEPGFTG---------------------------------- 433
             G +GLPG +GP GP GP G+PGF G                                  
Sbjct: 1428 MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 1487

Query: 434  ----------RPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLK 483
                      RPG PG  G  G  G  G  G+PG  G  G   L+GP+GPIGP+G  G K
Sbjct: 1488 PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG---LEGPSGPIGPKGERGAK 1544

Query: 484  GEPGLP--------GPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPG 534
            G+PG P        GPPG  G+ GEPG A   G PG+PG  G TGP G PG PGPPG PG
Sbjct: 1545 GDPGAPGVGLRGEMGPPGIPGQPGEPGYA-KDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603

Query: 535  AFDETG---IAGLHLPNGGVEG 553
              D +     A L    G V+G
Sbjct: 1604 QCDPSQCAYFASLAARPGNVKG 1625



 Score =  358 bits (920), Expect = 7e-99
 Identities = 231/550 (42%), Positives = 267/550 (48%), Gaps = 107/550 (19%)

Query: 84  KPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLR 143
           +P P  PP  P  PG   +G         PAG  G   MG AGP GLPG  G  G  G  
Sbjct: 450 EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKG--EMGVAGPMGLPGPKGDIGAIGPV 507

Query: 144 GEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRG 203
           G PG +G++G  G        GP G    G+ G+ G+PGPPG  G  G +GEPG      
Sbjct: 508 GAPGPKGEKGDVGI-------GPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGE----- 555

Query: 204 LKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGP 262
                 +G+PGLPG  G  G  GPPGLPGP G +G PGL G  G  G +GE G  G+ G 
Sbjct: 556 ------LGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGF 609

Query: 263 RGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-----GM 317
            G+PG  G +G PG  GV            GP G KG+ G  GPPG+ G         G 
Sbjct: 610 PGKPGDTGQQGRPGPSGVA-----------GPQGEKGDVGPAGPPGVPGSVVQQEGLKGE 658

Query: 318 PGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP 377
            G PGP+G +G  G PG  G  G  G DG PG QG +G  G  G PG  GL G +GPPGP
Sbjct: 659 QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718

Query: 378 KGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGG 437
            G  GP GP G PG+ G+ G  G  G PG  G  G  G +GPPGP G KGEPG  G  G 
Sbjct: 719 PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGL 778

Query: 438 P------------GVAGALGQKGDLGLPGQPGL------------RGPSGIPGL------ 467
           P            G+AG  G+KG+ GLPG PG             +G  G+PGL      
Sbjct: 779 PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838

Query: 468 QGPAGPIGPQGLPGL-------------------KGEPGLPGPPG-EGRAGEPGTAGPTG 507
           +G AGP GP GLPG                    KG+PGLPG PG +GR GE G  GPTG
Sbjct: 839 KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTG 898

Query: 508 PPGV---------------PGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVE 552
           PPG                PG+PG  G PGP GPPG  GAPG     G  G      G +
Sbjct: 899 PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG----ERGEK 954

Query: 553 GAVLGKGGKP 562
           GA  G+ G P
Sbjct: 955 GAA-GEEGSP 963



 Score =  236 bits (603), Expect = 4e-62
 Identities = 156/394 (39%), Positives = 181/394 (45%), Gaps = 73/394 (18%)

Query: 244 LPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGT 303
           +P  P        P  P P   P   G +    +  +     AG  G  G +G  G PG 
Sbjct: 438 IPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP 497

Query: 304 RGPPGLIGPTG--------------------------YGMPGLPGPKGDRGPAGVPGLLG 337
           +G  G IGP G                           G+PG PG  G +G  G PG LG
Sbjct: 498 KGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELG 557

Query: 338 DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG-------PG------ 384
           + G PGE G  G QGP GL GPPG  G+ GL G RG  G +GE G       PG      
Sbjct: 558 EPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTG 617

Query: 385 -----GPPGVPGIRGDQGPSGLAGKPGVPG----ERGLPGAHGPPGPTGPKGEP------ 429
                GP GV G +G++G  G AG PGVPG    + GL G  G PGP G +G P      
Sbjct: 618 QQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGAR 677

Query: 430 ---GFTGRPGGPGVAGALGQKGDLGLPGQP---GLRGPSGIPGLQGPAGPIGPQGLPGLK 483
              G  GR G PG+ G  G+KGD+G PG P   GL+GP G PG+ GP GP G  GLPG  
Sbjct: 678 GPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEI 737

Query: 484 GEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAG 543
           G PG PGPPG    G PG  GP GPPG PG+ G  G  G  G PG PG  G   E G+AG
Sbjct: 738 GFPGKPGPPGP--TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAG 795

Query: 544 LHLPNG-----------GVEGAVLGKGGKPQFGL 566
                G           GV G    +G K + GL
Sbjct: 796 RPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 829


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  432 bits (1110), Expect = e-121
 Identities = 279/631 (44%), Positives = 309/631 (48%), Gaps = 90/631 (14%)

Query: 23   GPRASSGG----GAGGAAGY-----APVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPM 73
            GP+ SSG     G  G AG      AP K  +    GPVGPP   G+      P P    
Sbjct: 618  GPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPT--- 674

Query: 74   DLKGEPGPPGKPGPRGPPGPPGFPGKPGM----------GKPGLHGQPGPAGPPGFSRM- 122
              +G PGPPG PG  G PG  G PG PG           G PG  G+PG  G PG   M 
Sbjct: 675  GFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMA 734

Query: 123  GKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPG 182
            G  GP G  G  GP G PG  G PG++G  G RG  G PG  G  G    G+ GA+G  G
Sbjct: 735  GGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI--GEKGAEGTAG 792

Query: 183  PPGFQGEPGPQGEPGPPGDRGLKGDNG----VGQPGLPGAPGQGGAPGPPGLPGPAGL-- 236
              G +G PGP G PGP G  G KG+ G    VG PG  G PG  G  GP G  G AG   
Sbjct: 793  NDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852

Query: 237  --GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG----------VGVPG 284
              G+PG+ G PG PG KG++G PG  G  G PG  GP G PG+ G           G PG
Sbjct: 853  PDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPG 912

Query: 285  AAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPG 343
            +AG  GP GP+GA G  G  G PG  GP G  G PG  G  GDRGPAG PG  GD+G+PG
Sbjct: 913  SAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPG 972

Query: 344  EDGEPGEQGPQGLGGP------------------PGLPGSAGLPGRRGPPGPKGEAGPGG 385
            EDG+PG  GP G  G                   PGLPG AG PG+ GP G  G+ GP G
Sbjct: 973  EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPG 1032

Query: 386  PPGVPGIRG---DQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAG 442
            P G PG  G   + GP G AG  G PG  G  G  G  G  GP G PG  G PG PG  G
Sbjct: 1033 PVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVG 1092

Query: 443  ALGQKGDLGLPGQ------PGLRGPSGIPGLQGPAGPIGP------------QGLPGLKG 484
            A G  G  G PG       PG  G  G+PG QGP G  G             +G  GL+G
Sbjct: 1093 APGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG 1152

Query: 485  EPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAG 543
             PG PGP GE G AG PG  GP GPPG  G  G  G PGP GP GPPG  G+  E G  G
Sbjct: 1153 LPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEG 1212

Query: 544  LHLPNG--GVEGAVLGKGGKPQFGLGELSAH 572
               P G  G  G   G  G     LG++  H
Sbjct: 1213 ---PPGEPGPPGPP-GPPGHLTAALGDIMGH 1239



 Score =  426 bits (1094), Expect = e-119
 Identities = 268/633 (42%), Positives = 307/633 (48%), Gaps = 140/633 (22%)

Query: 57  REGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-------GKPGLHG 109
           R  KGQ  E  L  +   ++G PGP G PG +GP G  G  G+PG        G+PG+ G
Sbjct: 109 RGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPG 168

Query: 110 QPGPAGPP---------GFSR----------------------------MGKAGPPGLPG 132
           QPG  GPP         G SR                            +G  GP GL G
Sbjct: 169 QPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQG 228

Query: 133 K---VGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG----------PSGITIPGKPGAQG 179
           +    GP G PG  G+PG  G  G RGP GPPG PG          P  +   G PGA+G
Sbjct: 229 QQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARG 288

Query: 180 VPGPPGF---------QGEPGPQGEPGPPGDRGLKGDNG-------VGQPGLP------- 216
            PG PG          +G  GP+GE G PG +G  G  G       +G  G+P       
Sbjct: 289 FPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG 348

Query: 217 --GAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKG 273
             GAPGQ GA G PG PGP G LG PG  G PG PG KGE+GP G  GP G  G  G  G
Sbjct: 349 PQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408

Query: 274 PPG-VDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY----------------G 316
           PPG V   G+PGA G  G  G  G  G PGT GPPG  GP G                 G
Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPG 468

Query: 317 MPGLPGPKGDRGPAGVP---GLLGDRGEPGEDGEPGEQGPQGLGGPP------GLPGSAG 367
            PG+PG KG+ GP G P   G+ G  G PGE+G+ G +G  G  GPP      G PG+ G
Sbjct: 469 DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRG 528

Query: 368 LPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGL---PGAHGPPGPTG 424
            PG  G PGPKG  G  GP G  G +G QG  G  G+PG+PG RGL   PG  GP G  G
Sbjct: 529 FPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588

Query: 425 PKGEPGFTGRPGGPGVAGALGQKGDLGL---------PGQPGLRGPSGIPGLQ------- 468
           P G PG  GRPG PG  G  GQ G +GL         PG+PG  G +G+PG +       
Sbjct: 589 PLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDG 648

Query: 469 --GPAGPIGPQGLPGLKGEPGLPGPPG----EGRAGEPGTAGPTGPPGVPGSPGITGPPG 522
             GP+GP+GP GL G +GE G PGP G     G  G PG  G  G  GVPG PG  GP G
Sbjct: 649 EVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLG 708

Query: 523 P------PGPPGPPGAPGAFDETGIAGLHLPNG 549
           P      PG  G PG  G   E G+AG H P+G
Sbjct: 709 PRGERGNPGERGEPGITGLPGEKGMAGGHGPDG 741



 Score =  422 bits (1084), Expect = e-118
 Identities = 262/560 (46%), Positives = 292/560 (52%), Gaps = 55/560 (9%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP  SSG  G+ G  G  P +   P  +G  G P  +G    L    PL      G PGP
Sbjct: 546  GPVGSSGPKGSQGDPG-RPGEPGLPGARGLTGNPGVQGPEGKLG---PLGAPGEDGRPGP 601

Query: 82   PGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGF-SRMGKAGPPGLPGKVGPPGQ 139
            PG  G RG PG  G PG  G  G PG  G+ G AG PG     GK G  G  G VGPPG 
Sbjct: 602  PGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGL 661

Query: 140  PGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPP 199
             G RGE G  G  G +G PGPPG PG  G     KPG QGVPG PG  G  GP+GE G P
Sbjct: 662  AGERGEQGPPGPTGFQGLPGPPGPPGEGG-----KPGDQGVPGDPGAVGPLGPRGERGNP 716

Query: 200  GDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGV 259
            G+RG  G  G+  PG  G  G  G  GP G PGP+G   PG  G PG  G  GE G  G 
Sbjct: 717  GERGEPGITGL--PGEKGMAGGHGPDGPKGSPGPSGT--PGDTGPPGLQGMPGERGIAGT 772

Query: 260  PGPRGEPGAVGPKGPPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRG---PPGLIGP 312
            PGP+G+ G +G KG  G  G     G+PG  G PGP GP+G KGEPG RG   PPG  G 
Sbjct: 773  PGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGN 832

Query: 313  TGY----GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGL------ 362
             G     G  G  G  G +GP G PG+ G+ GEPG+ G+ G  GPQGL G PG       
Sbjct: 833  PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGV 892

Query: 363  ------------PGSAGLPG---RRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGV 407
                        PG+ G PG   R GPPGP G  GP GP G P   G +GP GL G PG 
Sbjct: 893  PGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP---GKEGPPGLRGDPGS 949

Query: 408  PGERGLPGAHGPPGPTGPKGEPGFTGRP---GGPGVAGALGQKGDLGLPGQPGLRGPSGI 464
             G  G  G  GPPG  G KG+PG  G+P   G PG AG  GQ+G +G+PGQ G RG  G+
Sbjct: 950  HGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGL 1009

Query: 465  PGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGP 523
            PG  G  G +GP G  G KG PG  GPPG  G  GEPG  GP G  G PG  G  G  G 
Sbjct: 1010 PGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGD 1069

Query: 524  PGPPGPPGAPGAFDETGIAG 543
             G PGP G PG+    G  G
Sbjct: 1070 RGDPGPAGLPGSQGAPGTPG 1089



 Score =  417 bits (1072), Expect = e-116
 Identities = 260/612 (42%), Positives = 293/612 (47%), Gaps = 112/612 (18%)

Query: 31  GAGGAAGYAPVKYIQPMQKGPVGPPFREG-------KGQYLEMPLPLLPMDLKGEPGPPG 83
           G  G  G  PV      + GP GPP  +G       KG+    P P  P  + GEPG PG
Sbjct: 113 GQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGR----PGPRGPQGIDGEPGVPG 168

Query: 84  KPGPRGPPGPPGFPGKPGMGKP----------------------------------GLHG 109
           +PG  GPPG P  PG  G+ +P                                  GL G
Sbjct: 169 QPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQG 228

Query: 110 QPG---PAGPPG----------FSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRG 156
           Q G   P GPPG              G  GPPG PG+ G PG+ G  GE G  G  G RG
Sbjct: 229 QQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARG 288

Query: 157 PPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQ 212
            PG PGLPG  G      + G  G  G PG  G  G  GP G  GP G RG+ G+ G  +
Sbjct: 289 FPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERG--R 346

Query: 213 PGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGP 271
            G  GAPGQ GA G PG PGP G LG PG  G PG PG KGE+GP G  GP G  G  G 
Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406

Query: 272 KGPPG-VDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPA 330
            GPPG V   G+PGA G  G  G  G  G PGT GPPG  GP     PG PGP+G  GP 
Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGP-----PGSPGPQGSTGPQ 461

Query: 331 GVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP 390
           G+ G  GD   PG  G  GE GP+G  GP G+ G  G PG  G  GP+G+ G  GPPG  
Sbjct: 462 GIRGQPGD---PGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV 518

Query: 391 GIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDL 450
           G RG  G  G  G  G+PG +G  G  GP G +GPKG  G  GRPG PG+          
Sbjct: 519 GERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGL---------- 568

Query: 451 GLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG----------------E 494
                PG RG +G PG+QGP G +GP G PG   E G PGPPG                +
Sbjct: 569 -----PGARGLTGNPGVQGPEGKLGPLGAPG---EDGRPGPPGSIGIRGQPGSMGLPGPK 620

Query: 495 GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVE 552
           G +G+PG  G  G  GVPG  G  G  G  GP GP G PG   E G  G   P G  G+ 
Sbjct: 621 GSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP 680

Query: 553 G--AVLGKGGKP 562
           G     G+GGKP
Sbjct: 681 GPPGPPGEGGKP 692



 Score =  410 bits (1053), Expect = e-114
 Identities = 261/605 (43%), Positives = 301/605 (49%), Gaps = 68/605 (11%)

Query: 21  GCGPRASSGGGAGGAAGYAPVKYIQPMQ--KGPVGPPFREGKGQYLEMPLPLLPMDLKGE 78
           G G +     G+ G  G    + +Q  Q   GP GPP   G       P P+ P+  +G 
Sbjct: 203 GLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGD------PGPMGPIGSRGP 256

Query: 79  PGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGFS----------------- 120
            GPPGKPG  G PG  G PG+ G  G PG  G PG  G PG                   
Sbjct: 257 EGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGA 316

Query: 121 -----RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKP 175
                  G  GP G  G +GP G PG RG  G +G  G RG  G PG PGP G    G P
Sbjct: 317 PGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL--GIP 374

Query: 176 GAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG----VGQPGLPGAPGQGGAPGPPGLP 231
           G+ G PG PG +GE GP G  GP G +G +G+ G    VG PGLPGA G  G PG  G  
Sbjct: 375 GSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPT 434

Query: 232 GPAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPG 290
           G  G  G PG  G PG+PG +G +GP G+ G  G+PG  G KG  G  G   PG  G+ G
Sbjct: 435 GSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGE--PGPHGIQG 492

Query: 291 PQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGE 350
           P GP G +G+ G RG PG +GP G    G  G  G+RG  G  GL G +G  GE G  G 
Sbjct: 493 PIGPPGEEGKRGPRGDPGTVGPPG--PVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGS 550

Query: 351 QGPQGLGGPPGLPGSAGLPGRR---GPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGV 407
            GP+G  G PG PG  GLPG R   G PG +G  G  GP G PG  G  GP G  G  G 
Sbjct: 551 SGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQ 610

Query: 408 PGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGL 467
           PG  GLP   GP G +G  G+PG  G  G PG  GA G+ G++G  G  G  G +G  G 
Sbjct: 611 PGSMGLP---GPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGE 667

Query: 468 QGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGP------PGVPGSPGITGP 520
           QGP GP G QGLPG  G PG  G PG +G  G+PG  GP GP      PG  G PGITG 
Sbjct: 668 QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGL 727

Query: 521 P---------GPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKPQFGLGEL 569
           P         GP GP G PG  G   +TG  GL    G  G+ G    KG +   G+GE 
Sbjct: 728 PGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG--GIGEK 785

Query: 570 SAHAT 574
            A  T
Sbjct: 786 GAEGT 790



 Score =  301 bits (770), Expect = 2e-81
 Identities = 185/424 (43%), Positives = 216/424 (50%), Gaps = 39/424 (9%)

Query: 157 PPGPPGLPGPSGITIPGKPGAQGVPGPPGF-QGEPGPQGEPG-PPGDRGLKGDNGVGQPG 214
           P  PPG   P     PG        G   F +G  G +GEPG  P   G++G  G   P 
Sbjct: 85  PVTPPGECCPVCSQTPGG-------GNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGP- 136

Query: 215 LPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGP 274
            PG+ G  G  GP G PGP G    G+DG PG PG  G  GPPG P   G  G   P   
Sbjct: 137 -PGSQGPRGERGPKGRPGPRG--PQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSA 193

Query: 275 P--GVD---GVG-----VPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPK 324
              G+D   G+G     +PG+ G  GP+GP G +G+ G  GP G  G  G   PG  GP 
Sbjct: 194 QMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGD--PGPMGPI 251

Query: 325 GDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPG 384
           G RGP G PG  G+ GEPG +G PGE G  G  G  G PG+ GLPG +G  G KG  GP 
Sbjct: 252 GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311

Query: 385 GPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGAL 444
           G  G PG +G+ GP+G  G  G  G RG+PG  G  GP G  G+ G  G PG PG  G L
Sbjct: 312 GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371

Query: 445 GQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTA 503
           G  G  G PG PG++G +G  G +GP GP G +G  G  G  G PG PG  G  G PG  
Sbjct: 372 GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAK 431

Query: 504 GPTGPPGVPGSPGITGPPGPPGP------------PGPPGAPGAFDETGIAGLHLPNGGV 551
           GPTG PG  G PG  GPPG PGP            PG PG PG   E G  G   P+ G+
Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPH-GI 490

Query: 552 EGAV 555
           +G +
Sbjct: 491 QGPI 494



 Score =  223 bits (568), Expect = 5e-58
 Identities = 151/378 (39%), Positives = 174/378 (46%), Gaps = 67/378 (17%)

Query: 24   PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPG 83
            P A+   G+ G  G  P     P   GP+G P +EG            P  L+G+PG  G
Sbjct: 905  PGATGFPGSAGRVG-PPGPAGAPGPAGPLGEPGKEG------------PPGLRGDPGSHG 951

Query: 84   KPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRM-------------------GK 124
            + G RGP GPPG PG  G   PG  GQPGP GPPG +                     G 
Sbjct: 952  RVGDRGPAGPPGGPGDKG--DPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGL 1009

Query: 125  AGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT-IPGKPGA------ 177
             GP G PGKVGP G  G +G PG  G  G  GP G PG  GP+G    PG+ GA      
Sbjct: 1010 PGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGD 1069

Query: 178  QGVPGP---PGFQGEPGPQGEPGPPGDRGLKGDNGVGQP-GLPGAPGQGGAPGPPGLPGP 233
            +G PGP   PG QG PG  G  G PGD G +GD G   P G PG  G+ G PGP G  G 
Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129

Query: 234  AG-------------LGKPGLDGLPGAPGDKGESGPPGVPGP---RGEPGAVGPKGPPGV 277
             G              G  GL GLPG PG  GE G  G+PGP   RG PG VGP G  G 
Sbjct: 1130 KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGN 1189

Query: 278  DG----VGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVP 333
             G    +G PG  G  G  GP G  GEPG  GPPG  G     +  + G   +  P  +P
Sbjct: 1190 PGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLP 1249

Query: 334  GLLGDRGEPGEDG--EPG 349
                D+  P +    +PG
Sbjct: 1250 EFTEDQAAPDDKNKTDPG 1267


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  431 bits (1108), Expect = e-120
 Identities = 271/625 (43%), Positives = 311/625 (49%), Gaps = 112/625 (17%)

Query: 31   GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRG- 89
            G  G  G+ P     P   G  G   R G     E+P P      +G+ G PG  G +G 
Sbjct: 683  GPPGPKGF-PGPQGAPGLSGSDGHKGRPGTPGTAEIPGP---PGFRGDMGDPGFGGEKGS 738

Query: 90   -PPGPPGFPGKPGM-GKPGLHGQP--GPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGE 145
             P GPPG PG PG+ G+ G+ G P  G  GPPG  + G +G PG+ G  G PG PG  G 
Sbjct: 739  SPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPG--KRGLSGVPGIKGPRGDPGCPGAEGP 796

Query: 146  PGIRGDQGLRGPPGP------PGLPGPSGIT-------IPGKPGAQGVPGPPGFQGEPGP 192
             GI G  GL+GP G       PG+PGP G +       IPG+PG  G PG PG  G  G 
Sbjct: 797  AGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQ 856

Query: 193  QGEPGPPGDRGLKGDNGV-------GQPGLPGAPG---QGGAPGPPGLPGPAGL------ 236
             G+ GPPG  G+KG  G+       G PGLPG PG     G PGPPG  GP GL      
Sbjct: 857  PGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGF 916

Query: 237  ----GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV------------ 280
                GKPG +G PGA G+ GE G  G+PG RG  GA G  GPPG +G             
Sbjct: 917  PGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGE 976

Query: 281  -GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY--------GMPGLPGPKGDRGPAG 331
             G PG  G PG +G  G  G  G RG PG  GP G+        G PG PGP G  G  G
Sbjct: 977  PGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTG 1036

Query: 332  VPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPG----RRGPPGPKGEAGPGGPP 387
            + G +G  G PG+ GEPG  GP G  G  G  G  G  G      GPPGPKGE G  G P
Sbjct: 1037 LRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCP 1096

Query: 388  GVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQK 447
            G  G  G+QG  G+ G  G PG  G PG+ GPPG  G  G PG  G+PG  G  G  G +
Sbjct: 1097 GHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQ 1156

Query: 448  GDLGLPGQPGLRGPSGIPGLQG-----------------PAGPIGPQGLPGLKGEPGLPG 490
            GD G+PG PG++GPSG PGL G                   GP GP G+PGLKGE G PG
Sbjct: 1157 GDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPG 1216

Query: 491  PPG---------EGRAGEPGTAGPTGPPGV----------PGSPGITGPPGPPGP---PG 528
             PG         +G  G PG++GP GP G           PG PG  GPPGP GP   PG
Sbjct: 1217 SPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPG 1276

Query: 529  PPGAPGAFD----ETGIAGLHLPNG 549
            PPG PG+ D    E G  GL  P G
Sbjct: 1277 PPGLPGSVDLLRGEPGDCGLPGPPG 1301



 Score =  427 bits (1098), Expect = e-119
 Identities = 281/671 (41%), Positives = 324/671 (48%), Gaps = 113/671 (16%)

Query: 31   GAGGAAGY-----APVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP---- 81
            G  G  GY     AP    QP   GP GP   +G       P    P  L G PGP    
Sbjct: 837  GQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDD 896

Query: 82   --PGKPGPRGPPGPPGFPGKPG-MGKPGLHGQPGPAGPPGFSRM----GKAGPPGLPGKV 134
              PG PGP+GP G PGFPG PG  GKPG  G PG  G PG   M    G  G  G  G +
Sbjct: 897  GLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAI 956

Query: 135  GPPG---------QPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPG--- 182
            GPPG         Q G  GEPG  GD G  G  G  G PG  G    G+PG  G PG   
Sbjct: 957  GPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRR--GEPGRYGPPGFHR 1014

Query: 183  -PPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPG--------- 232
              PG +G+PGP G PGPPG  GL+G   +G PGLPG  G+ G+PGPPG  G         
Sbjct: 1015 GEPGEKGQPGPPGPPGPPGSTGLRGF--IGFPGLPGDQGEPGSPGPPGFSGIDGARGPKG 1072

Query: 233  -----------PAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGP---KGPPGVD 278
                       P   G+PG  G PG  G  GE G PG+ GPRG PG  GP    GPPG  
Sbjct: 1073 NKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCP 1132

Query: 279  GV-GVPGAAGLPGPQG---PSGAKGEPGTRGPPGLIGPTGY----GMPGLPGPKGDRG-- 328
            G  G+PG  G PG  G   P G +G+PG  GPPG+ GP+G     G+ GL G KG +G  
Sbjct: 1133 GDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGAS 1192

Query: 329  ---------PAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGR-------- 371
                     P G+PGL G+RG+PG  G     GP+G  GPPG PGS+G PG         
Sbjct: 1193 GLHDVGPPGPVGIPGLKGERGDPGSPGI-SPPGPRGKKGPPGPPGSSGPPGPAGATGRAP 1251

Query: 372  -----------RGPPGPKGEAGPGGPPGVPG----IRGDQGPSGLAGKPGVPGERGLPGA 416
                       +GPPGP G  G  GPPG+PG    +RG+ G  GL G PG PG  G PG 
Sbjct: 1252 KDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGY 1311

Query: 417  HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGP 476
             G PG  G  G+ G  G PG  G  G  G  G+ GLPG PG +GP+G+PG +G  GP   
Sbjct: 1312 KGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPAD 1371

Query: 477  ----QGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA 532
                  +PGL G PG+ GP  EG  G PG  GP+G PG  G PG+ G  G  G PG PG 
Sbjct: 1372 VDDCPRIPGLPGAPGMRGP--EGAMGLPGMRGPSG-PGCKGEPGLDGRRGVDGVPGSPGP 1428

Query: 533  PGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPV 592
            PG   +TG  G   P G      +G  G   FG G L        +     P    GMP 
Sbjct: 1429 PGRKGDTGEDG--YPGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQTDQEPTCPLGMP- 1485

Query: 593  KFDRTLYNGHS 603
                 L+ G+S
Sbjct: 1486 ----RLWTGYS 1492



 Score =  407 bits (1045), Expect = e-113
 Identities = 277/665 (41%), Positives = 314/665 (47%), Gaps = 128/665 (19%)

Query: 31   GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 90
            G  G  G+ P +Y +    GP GPP   G+       + + P   +G PG PG PG  G 
Sbjct: 367  GPPGDPGF-PGRYGETGDVGPPGPPGLLGRPGEACAGM-IGPPGPQGFPGLPGLPGEAGI 424

Query: 91   PG-PPGFPGKPGM-GKPGLHGQPGPAGPPGFS----RMGKAGPPGLPGKVGPPGQPGLRG 144
            PG P   PGKPG  G PGL G PG  G PG S     +G  GP G+ GKVGPPG  G +G
Sbjct: 425  PGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKG 484

Query: 145  EPGIRG----DQGLRGPPGPPGLPGPSG----ITIPGKPGAQGVPGPPGFQGEPG---PQ 193
            E G  G    + G  GPPGPPGLPG  G    + +PG  G +G PGPPG +G PG     
Sbjct: 485  EKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKH 544

Query: 194  GEPGPPGDRGLKGDNGV-------------GQPGLPGAPG---------QGGAPGPPG-- 229
            G  GPPG++G KGD  V             G PG PG PG         + G PGPPG  
Sbjct: 545  GASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDH 604

Query: 230  ---------LPGPAG-------LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKG 273
                      PGP G       +G PGL G PG PG++G  G PG PG RG  G  G KG
Sbjct: 605  EDATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGERGHPGVPGHPGVRGPDGLKGQKG 663

Query: 274  --------------PPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY 315
                          PPG DG     G PG  G PG  G  G KG PGT G   + GP G+
Sbjct: 664  DTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGF 723

Query: 316  ----GMPGLPGPKGDR-----GPAGVPGLLGDRGEPGE--------------DGEPGEQG 352
                G PG  G KG       GP G PG+ G +G PG+               G PG +G
Sbjct: 724  RGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKG 783

Query: 353  PQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPG------------IRGDQGPSG 400
            P+G  G PG  G AG+PG  G  GPKG  G  G PGVPG            I G  G  G
Sbjct: 784  PRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPG 843

Query: 401  LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGG---PGVAGALGQKGDLGLPGQPG 457
              G PG PG +G PG  GPPGP G KG PG  GRPG    PG+ G  G  GD GLPG PG
Sbjct: 844  YPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPG 903

Query: 458  LRGPSGIPGLQG---PAGPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPG 513
             +GP G+PG  G     G  G +G PG KGEPG  G  G  G  G  G  G  GPPG  G
Sbjct: 904  PKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEG 963

Query: 514  SPGI---TGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELS 570
               I    G PG PGPPG  G PG   + G  G+    G       G+ G P F  GE  
Sbjct: 964  EMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEP-----GRYGPPGFHRGEPG 1018

Query: 571  AHATP 575
                P
Sbjct: 1019 EKGQP 1023



 Score =  404 bits (1038), Expect = e-112
 Identities = 284/669 (42%), Positives = 326/669 (48%), Gaps = 108/669 (16%)

Query: 7   PLSSLLLLLLV-LVLGCGPR--ASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQY 63
           P S +L+L  V  V G G +     GG         P K      +GP GPP  +G    
Sbjct: 23  PWSLILILFSVQYVYGSGKKYIGPCGGRDCSVCHCVPEKG----SRGPPGPPGPQGPIGP 78

Query: 64  LEMPLPL---LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAGPPGF 119
           L  P P+       ++G+ GPPG  G +G  GP G PG PG+ G PG  G PGP G PG 
Sbjct: 79  LGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGM 138

Query: 120 S-RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGD-----------QGLRGPPGPPGLPGPS 167
           S   G  G PG PG  G  G  G  G PG +G+           +G++G  G PGLPG  
Sbjct: 139 SGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPG-- 196

Query: 168 GITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV---GQPGLPGAPGQGGA 224
              +PG  GA G  GP G+ GEPG  G PG PG  GLKG+ GV   GQ G PG  GQ G+
Sbjct: 197 ---LPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGS 253

Query: 225 PGPPGLPGPAGL----------GKPGLDGLPGAPGDKGES--------GPPGVPGPRGEP 266
           PGP  L  P             G PG+ GLPG PG KGES        G PG PGPRG+P
Sbjct: 254 PGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDP 313

Query: 267 GAVGPKGPPGVDG----VGVPGAAGLPGPQGPSGAKGEPGTRG-----PPGLIGPTG-YG 316
           G+ G  G PG+ G    VG PG  GL GP+G  G +G PG  G     P  L GP G  G
Sbjct: 314 GSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPG 373

Query: 317 MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGR-RGPP 375
            PG  G  GD GP G PGLLG  GE    G  G  GPQG  G PGLPG AG+PGR    P
Sbjct: 374 FPGRYGETGDVGPPGPPGLLGRPGEACA-GMIGPPGPQGFPGLPGLPGEAGIPGRPDSAP 432

Query: 376 GPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKG-------- 427
           G  G+ G  G PG PG++G  G S +    G PG +G+ G  GPPG  GPKG        
Sbjct: 433 GKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLC 492

Query: 428 --EPGFTGRPGGPGVAGALGQKGDLGL---------PGQPGLRGPSGIPGLQGPAGPIGP 476
             EPG  G PG PG+ G  G KGDLGL         PG PG  GP G+PG  G +GP G 
Sbjct: 493 ACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGN 552

Query: 477 QG---------LPGLKGE------PGLPGPPG----EGRAGEPGTAGPTG-----PPGVP 512
           +G         + G KGE      PG PG PG    +G AGE G  GP G      PG  
Sbjct: 553 KGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGK 612

Query: 513 GSPGITGPPGPPGPPGPPGA--PGAFDETGIAGL--HLPNGGVEGAVLGKGGKPQFGLGE 568
           G PG  GPPG  GP GPPG   PG   E G  G+  H    G +G    KG      +  
Sbjct: 613 GFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTY 672

Query: 569 LSAHATPAF 577
              H  P F
Sbjct: 673 PGRHGPPGF 681



 Score =  403 bits (1036), Expect = e-112
 Identities = 286/720 (39%), Positives = 331/720 (45%), Gaps = 167/720 (23%)

Query: 24  PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPG 83
           P      GAGG AG  P  Y  P + G VGPP + G+      P     + +KG+ G PG
Sbjct: 195 PGLPGSWGAGGPAG--PTGY--PGEPGLVGPPGQPGRPGLKGNP----GVGVKGQMGDPG 246

Query: 84  KPGPRGPPGP------PGF---PGKPGM-GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGK 133
           + G +G PGP      P F    G+ G+ G PG+ G PGP G  G S +G  G  G+PG 
Sbjct: 247 EVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGF 306

Query: 134 VGP---------PGQPGLRGEPGIRGDQGL------RGPPGPPGLPGPSGITIPGKPGAQ 178
            GP         PG PGL+GE G+ GD GL      +G PG  G PGP G+ +      +
Sbjct: 307 PGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLK 366

Query: 179 GVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGL-- 236
           G PG PGF G  G  G+ GPPG  GL G  G    G+ G PG  G PG PGLPG AG+  
Sbjct: 367 GPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPG 426

Query: 237 ---------GKPGLDGLPGAP---------------------GDKGESGPPGVPGPRG-- 264
                    GKPG  GLPGAP                     G KG+ GPPG  GP+G  
Sbjct: 427 RPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEK 486

Query: 265 --------EPGAVGPKGPPGVDG-VGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG- 314
                   EPG +GP GPPG+ G  G  G  GLPG  G  G  G PG  GPPGL G  G 
Sbjct: 487 GNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGA 546

Query: 315 YGMPGLPGPKGD------------RGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPG- 361
            G PG  G KGD            RGP G PG  G  G  G DG  GE+G     GPPG 
Sbjct: 547 SGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDP---GPPGD 603

Query: 362 ----LPGSAGLPGRRGPPGPKGEAGPGGPPGV--PGIRGDQGPSGLAGKPGVPGERGL-- 413
                PG  G P   GP GP G+AGP GPPG+  PG  G++G  G+ G PGV G  GL  
Sbjct: 604 HEDATPGGKGFP---GPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKG 660

Query: 414 ------------PGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLG------LPGQ 455
                       PG HGPPG  GP G  GF G  G PG++G+ G KG  G      +PG 
Sbjct: 661 QKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGP 720

Query: 456 PGLRGPSGIPGLQG-----PAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPG 510
           PG RG  G PG  G     P GP GP G PG+ G+ G+PG P  G  G PG  G +G PG
Sbjct: 721 PGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPG 780

Query: 511 V------PGSPGITGPPGPP---------------GPPGPPGAPGAFDETGIAGLHLPNG 549
           +      PG PG  GP G P               G PG PG PG   E G  G+    G
Sbjct: 781 IKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPG 840

Query: 550 --GVEGAVLGKGGKPQFG----------------LGELSAHATPAFTAVLTSPFPASGMP 591
             G  G+    GGK Q G                 G   AH  P    +   PF   G+P
Sbjct: 841 LPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGI-PGPFGDDGLP 899



 Score =  376 bits (965), Expect = e-104
 Identities = 280/696 (40%), Positives = 316/696 (45%), Gaps = 181/696 (26%)

Query: 23  GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREG-KGQYLEMPLPLLPMDLKGEPG 80
           GP+   G  GA G  G +  K +    +G  GPP   G KG      +P  P  L G PG
Sbjct: 71  GPQGPIGPLGAPGPIGLSGEKGM----RGDRGPPGAAGDKGDKGPTGVPGFP-GLDGIPG 125

Query: 81  PPGKPGPRGPPG---------PPGFPGKPG-MGKPGLHGQPGPAGPPGFSRM-------- 122
            PG PGPRG PG          PGFPG  G +G  G  G PG  G  G S          
Sbjct: 126 HPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGI 185

Query: 123 -GKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG---------ITIP 172
            G  G PGLPG  G  G  G  G  G  G+ GL GPPG PG PG  G         +  P
Sbjct: 186 QGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDP 245

Query: 173 GKPGAQGVPGP---------------PGFQGEPGPQGEPGPPGDR-----GLKGDNGV-G 211
           G+ G QG PGP                G +G PG  G PGPPG +     G KG+ G+ G
Sbjct: 246 GEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPG 305

Query: 212 QPGLPGAPGQGGAPGPPGLPGPAGL-GKPGLDGL---PGAPGDKGESGPPGV-------- 259
            PG  G PG  G+PG PGL G  GL G PGL GL    G PG++G  GPPGV        
Sbjct: 306 FPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPL 365

Query: 260 ---------PGPRGEPGAVGPKGPPGVDG---------------VGVPGAAGLPGPQG-- 293
                    PG  GE G VGP GPPG+ G                G PG  GLPG  G  
Sbjct: 366 KGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIP 425

Query: 294 --PSGAKGEPGTRGPPGLIGPTG-YGMPGL---------PGPKGDRGPAGVPGLLGDRGE 341
             P  A G+PG  G PGL G  G  G+PG          PGP+G +G  G PG  G +GE
Sbjct: 426 GRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGE 485

Query: 342 PGEDG----EPGEQGPQG-------------LG-----------GPPGLPGSAGLPGRRG 373
            G +G    EPG  GP G             LG           GPPG  G  GLPG+ G
Sbjct: 486 KGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHG 545

Query: 374 PPGP------------------KGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPG-----E 410
             GP                  KGE GP GPPG PG  G  G  G AG+ G PG     E
Sbjct: 546 ASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHE 605

Query: 411 RGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGI------ 464
              PG  G PGP GP G+ G  G P G G  G  G++G  G+PG PG+RGP G+      
Sbjct: 606 DATPGGKGFPGPLGPPGKAGPVG-PPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGD 664

Query: 465 --------PGLQGPA---GPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGV- 511
                   PG  GP    GP GP+G PG +G PGL G  G +GR G PGTA   GPPG  
Sbjct: 665 TISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFR 724

Query: 512 --PGSPGITGPPG--PPGPPGPPGAPGAFDETGIAG 543
              G PG  G  G  P GPPGPPG+PG   + GI G
Sbjct: 725 GDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPG 760



 Score =  244 bits (623), Expect = 2e-64
 Identities = 168/409 (41%), Positives = 196/409 (47%), Gaps = 46/409 (11%)

Query: 250 DKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-------GVPGAAGLPGPQGPSGAKGEPG 302
           +KG  GPPG PGP+G  G +G  GP G+ G        G PGAAG  G +GP+G  G PG
Sbjct: 60  EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPG 119

Query: 303 TRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQG-----L 356
             G PG  GP G  G PG+ G  G RG  G PG  G  G  G  G PGE+G +G     L
Sbjct: 120 LDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFIL 179

Query: 357 GGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGER--GLP 414
           G   G+ G  G PG  G PG  G  GP GP G PG  G  GP G  G+PG+ G    G+ 
Sbjct: 180 GAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVK 239

Query: 415 GAHGPPGPTGPKGEPGFTGRPGGP------GVAGALGQKGDLGLPGQPGLRGPSGI--PG 466
           G  G PG  G +G PG T     P      G  G  G  G +GLPG PG +G SGI   G
Sbjct: 240 GQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKG 299

Query: 467 LQGPAGPIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPG--- 522
            +G  G  GP+G PG  G PG PG  GE G  G+PG  G  GP G PG+ G  GPPG   
Sbjct: 300 EKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLV 359

Query: 523 -PP----GPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGL-------GELS 570
            PP    GPPG PG PG + ETG  G   P G     +LG+ G+   G+       G   
Sbjct: 360 TPPLPLKGPPGDPGFPGRYGETGDVGPPGPPG-----LLGRPGEACAGMIGPPGPQGFPG 414

Query: 571 AHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYN--PATGIFTCPVG 617
               P    +   P  A G P K       G  G    P + +  C VG
Sbjct: 415 LPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVG 463


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  431 bits (1107), Expect = e-120
 Identities = 286/670 (42%), Positives = 320/670 (47%), Gaps = 155/670 (23%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GPR ++G  GA G +G            GP GPP   G               L G  GP
Sbjct: 764  GPRGATGKSGAKGTSG----------GDGPHGPPGERG---------------LPGPQGP 798

Query: 82   PGKPGPRGPPGPPG---FPGKPGM-GKPGLHGQPGPAGPPGF----SRMGKAGPPGLPGK 133
             G PGP+GPPGPPG    PG PG  G+ G  G+ GP GPPG        G+ GP G  G 
Sbjct: 799  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858

Query: 134  VGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG---PSGIT-IPGKPGAQGVPGPPGFQGE 189
             GPPG PG +G PG  G +G +G PGPPG PG   P+G+   PG+ G  G  G PG +G 
Sbjct: 859  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918

Query: 190  PGPQGEPGP---PGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPG------------- 232
             GP G PGP   PG+RG  G  G +G PG PG  G  GA G  G+PG             
Sbjct: 919  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 978

Query: 233  --PAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGL 288
              P GL G  G  G+ G  GDKGE G PG  G +G  G  GP GPPG  G VG PGAAG 
Sbjct: 979  QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1038

Query: 289  PG------PQGPSGAKGEPGTRG---PPGLIG------PTG----------YGMPGLPGP 323
             G      PQG  GAKG+ GTRG   PPG IG      P+G           G PG PGP
Sbjct: 1039 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1098

Query: 324  KGDRGPAGV------PGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPG---------SAGL 368
            +G  GP G       PG +G+ G PGE GEPGE G  G+ G PG+ G          +G 
Sbjct: 1099 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1158

Query: 369  PGRRGPPGPKGEAGPGGPPGVPG---IRGDQGPSGLAG---------------KPGVPGE 410
            PG  GPPGPKG  G  GP G PG     GD GP G  G               +PG PG 
Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1218

Query: 411  RGLPGAHGPPGPTG---PKGEPGFTGRPGG------------PGVAGALGQKGDLGLPGQ 455
             G  G +GPPGP G   P G PG  GR GG            PG  G +G  G  G PG 
Sbjct: 1219 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1278

Query: 456  PGLRGPSGIPGLQG---------PAGPIGPQGLPGLKGEPG------------LPGPPGE 494
             GLRG  G  G QG         P GP+GP GLPGL+G+ G            L GPPGE
Sbjct: 1279 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1338

Query: 495  -GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGV-E 552
             G  G+ G  GP G PG  G  GI G  GP GP GPPG PG     G  G   P G   E
Sbjct: 1339 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1398

Query: 553  GAVLGKGGKP 562
              V G  G P
Sbjct: 1399 KGVQGPPGHP 1408



 Score =  430 bits (1105), Expect = e-120
 Identities = 259/561 (46%), Positives = 290/561 (51%), Gaps = 90/561 (16%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM----GKP 105
            GP GPP  +G      +P        KG+PGPPG PG  GP G  GFPG+ G+    G P
Sbjct: 860  GPPGPPGEQG------LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 913

Query: 106  GLHGQPGPAGPPG-FSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLP 164
            GL G  GP+GPPG     G+ G  G  G +GPPG+PG +G PG  G++G+ G  GP G  
Sbjct: 914  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973

Query: 165  GPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-------------VG 211
            G  G+   G  G  G  GPPG  GE G +GE G PG +G KG+ G             VG
Sbjct: 974  GRDGVQ--GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031

Query: 212  QPGLPGAPGQGGAPGPPGL---------------PGPAGL-GKPGLDGLPGAPGDKGESG 255
            QPG  GA G+ GA GP G                PGP GL G PG  G  G  GD G  G
Sbjct: 1032 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1091

Query: 256  PPGVPGPRGEPG---AVGPKGPPG-VDGVGVPGAAGLPGPQGPSGAKGEPGTRGP----- 306
            PPG PGPRG  G   A GP+GPPG V  +G PG  G PG  G  G +GEPG +GP     
Sbjct: 1092 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1151

Query: 307  -------------PGLIGPTG----------YGMPGLPGPKGDRGPAGVPGLLGDRGEPG 343
                         PG  GPTG           G PG PGP G+ GP G  G  GDRGE G
Sbjct: 1152 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG 1211

Query: 344  EDGEPGEQGPQGLGGPPG---LPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG 400
            E G+PG  GP G  GPPG     G AG PG  G  G KG  G  G  G PG  G  GP+G
Sbjct: 1212 EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1271

Query: 401  LAGKPGVPGERGLPGA---HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG 457
             AGKPG  G RGLPG+    G PG TG  G PG  G PG PG+ G  G KG+ G PG  G
Sbjct: 1272 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1331

Query: 458  LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPG---------PPG-EGRAGEPGTAGPTG 507
            L GP G  G +G  G  GPQG PG KGE G+PG         PPG  G AG  G  G TG
Sbjct: 1332 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG 1391

Query: 508  PPGVPGSPGITGPPGPPGPPG 528
            P G  G  G+ GPPG PGPPG
Sbjct: 1392 PGGPKGEKGVQGPPGHPGPPG 1412



 Score =  416 bits (1068), Expect = e-116
 Identities = 259/605 (42%), Positives = 299/605 (49%), Gaps = 87/605 (14%)

Query: 31  GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 90
           G  G  GY      +P   G  G P  +G+   L    P  P  L G PG  G+ G  G 
Sbjct: 401 GPPGPMGYTG----RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 456

Query: 91  PGPPGFPGKPGM-------GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLR 143
            G  G PG PG+       G PGL G+ G  G  G    G  GPPG  G+ G  G+ G R
Sbjct: 457 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG--AQGLPGPPGEDGERGDDGEIGPR 514

Query: 144 GEPGIRGDQGLRGPPGPPGLPGPSGIT-------IPGKPGAQGVPGPPGFQGEPGPQGEP 196
           G PG  G +GL GP GPPG+PGP G+          G  G QG PGPPG QG PG QG P
Sbjct: 515 GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 574

Query: 197 GPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAG-------------LGKP--- 239
           GP G  G  G+ G  G+PGLPG PG  G PG PG  GP G             LG P   
Sbjct: 575 GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 634

Query: 240 ---GLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSG 296
              G+DG+ G  G KGE G  G PG +G+ G  G +G      VGVPG+ G  GP+GP G
Sbjct: 635 GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE-----VGVPGSRGEDGPEGPKG 689

Query: 297 AKGEPGTRGPPGLIGPTG-------------------YGMPGLPGPKGDRGPAGVPGLLG 337
             G  G  GPPGL+G  G                    G PG PG  G++G  G+ G  G
Sbjct: 690 RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSG 749

Query: 338 DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
            RGE G  G  G++GP+G  G  G  G++G  G  GPPG +G  GP GP G PG +G  G
Sbjct: 750 PRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG 809

Query: 398 PSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG 457
           P G  G PG PG+RG  G  G  GP GP   PG  G  G  G  G +G++G  G PG PG
Sbjct: 810 PPGKDGLPGHPGQRGEVGFQGKTGPPGP---PGVVGPQGAAGETGPMGERGHPGPPGPPG 866

Query: 458 LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE----GRAGEP---GTAGPTGPPG 510
            +G  G  G +G  G  GP G PG  G  GL G PGE    G AG P   G  GP+GPPG
Sbjct: 867 EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 926

Query: 511 VPGSP------GITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGAV--LG 557
             GSP      G  GP GPPG PGP G PGA  E G+ G   P G     GV+G V   G
Sbjct: 927 PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 986

Query: 558 KGGKP 562
             G P
Sbjct: 987 PAGPP 991



 Score =  414 bits (1064), Expect = e-115
 Identities = 253/539 (46%), Positives = 277/539 (51%), Gaps = 55/539 (10%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG-MGKPGLH 108
            GP GPP          +P P     + G  GP G  GP+G PGPPG  G PG  G PG  
Sbjct: 527  GPKGPP---------GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 577

Query: 109  GQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG 168
            G  GP G  G    GK G PG+PG  GPPG PG  G PG +G+QG  GP GP G PGP G
Sbjct: 578  GAIGPHGEKG--PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 635

Query: 169  ITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGA--- 224
            +      G  G+ G  G +GE G  G PG  GD G+KGD G VG PG  G  G  G    
Sbjct: 636  VK-----GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR 690

Query: 225  ------PGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGV 277
                  PGPPGL G  G LG PGL G PG  G KG  G PG PG  GE GA G  G  G 
Sbjct: 691  TGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 750

Query: 278  DGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGL 335
             G  G  G  G  GP+G +G  G  GT G  G  GP G  G+PG  GP G  GP G PG 
Sbjct: 751  RGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP 810

Query: 336  LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP----- 390
             G  G PG  G+ GE G QG  GPPG PG  G  G  G  GP GE G  GPPG P     
Sbjct: 811  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 870

Query: 391  -------GIRGDQGPSGLAGKP------GVPGERGLPGAHGPPGPTGPKGEPGFTGRPGG 437
                   G +GD GP G  GK       G PGERGLPG  G PG  G +G  G  G  G 
Sbjct: 871  PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 930

Query: 438  PGVAGALGQKGDLGLPGQPGLRGP---SGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG- 493
            PG  GA G  G +G PG+PG +GP   +G  G+ G  GPIGP G  G++G  GLPGP G 
Sbjct: 931  PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 990

Query: 494  EGRAGEPGTAGPTGPP---GVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
             G AGE G  G  G P   G  G+ G  GPPGPPGP GP G PGA    G  G   P G
Sbjct: 991  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG 1049



 Score =  368 bits (944), Expect = e-101
 Identities = 234/579 (40%), Positives = 272/579 (46%), Gaps = 123/579 (21%)

Query: 81  PPGKPGPRGPPGPPGFPGKPGMGKPGL--HGQPGPAGPPGFSRMGKAGPPGLPGKVGPPG 138
           PP +    GP G  G  G+P + +PG+   G PGP GP G               +GPPG
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL--------------IGPPG 328

Query: 139 QPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGA--------------------- 177
              ++G PG  GD G RGPPG  GLPG  G   PG PG                      
Sbjct: 329 ---IQGNPGPVGDPGERGPPGRAGLPGSDG--APGPPGTSLMLPFRFGSGGGDKGPVVAA 383

Query: 178 ----------------QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG----------VG 211
                           +G PGP G+ G PGP G+PG PG +G  GD G           G
Sbjct: 384 QEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTG 443

Query: 212 QPGLPGAPGQGGAPGPPGLPGPAGL-GKPGLDGLPGAPGDKGE---------SGPPGVPG 261
            PG  G  G+ GA G  G+PG  G+ G  G DGLPG PG+KG           GPPG  G
Sbjct: 444 PPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 503

Query: 262 PRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGL 320
            RG+ G +GP+G PG       G  GL GP+GP G  G PG RG  G  GP G  G  G 
Sbjct: 504 ERGDDGEIGPRGLPGES-----GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 558

Query: 321 PGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGE 380
           PGP G +G  G  GL G +G  G  GE G QG  GL G PG  G  G PG+ GPPG KG 
Sbjct: 559 PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618

Query: 381 AGPGGP------------PGVPGIRGDQGPSGLAGKPGVP------------GERGLPGA 416
            GP GP             GV GIRG +G  G  G+ G P            GE G+PG+
Sbjct: 619 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 678

Query: 417 HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS---GIPGLQGPAGP 473
            G  GP GPKG  G TG PG PG+ G  G+ G  GLPG PG +GP    G PG  G +G 
Sbjct: 679 RGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 738

Query: 474 IGPQGLPGLKGEPGLPGPPG----------EGRAGEPGTAGPTGPPGVPGSPGITGPPGP 523
            G +GL G  G  G  GP G           G++G  GT+G  GP G PG  G+ GP GP
Sbjct: 739 KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798

Query: 524 PGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKP 562
            G PGP G PG   + G+ G   P    E    GK G P
Sbjct: 799 NGFPGPKGPPGPPGKDGLPG--HPGQRGEVGFQGKTGPP 835


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  431 bits (1107), Expect = e-120
 Identities = 286/670 (42%), Positives = 320/670 (47%), Gaps = 155/670 (23%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GPR ++G  GA G +G            GP GPP   G               L G  GP
Sbjct: 743  GPRGATGKSGAKGTSG----------GDGPHGPPGERG---------------LPGPQGP 777

Query: 82   PGKPGPRGPPGPPG---FPGKPGM-GKPGLHGQPGPAGPPGF----SRMGKAGPPGLPGK 133
             G PGP+GPPGPPG    PG PG  G+ G  G+ GP GPPG        G+ GP G  G 
Sbjct: 778  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837

Query: 134  VGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG---PSGIT-IPGKPGAQGVPGPPGFQGE 189
             GPPG PG +G PG  G +G +G PGPPG PG   P+G+   PG+ G  G  G PG +G 
Sbjct: 838  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897

Query: 190  PGPQGEPGP---PGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPG------------- 232
             GP G PGP   PG+RG  G  G +G PG PG  G  GA G  G+PG             
Sbjct: 898  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957

Query: 233  --PAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGL 288
              P GL G  G  G+ G  GDKGE G PG  G +G  G  GP GPPG  G VG PGAAG 
Sbjct: 958  QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1017

Query: 289  PG------PQGPSGAKGEPGTRG---PPGLIG------PTG----------YGMPGLPGP 323
             G      PQG  GAKG+ GTRG   PPG IG      P+G           G PG PGP
Sbjct: 1018 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1077

Query: 324  KGDRGPAGV------PGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPG---------SAGL 368
            +G  GP G       PG +G+ G PGE GEPGE G  G+ G PG+ G          +G 
Sbjct: 1078 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1137

Query: 369  PGRRGPPGPKGEAGPGGPPGVPG---IRGDQGPSGLAG---------------KPGVPGE 410
            PG  GPPGPKG  G  GP G PG     GD GP G  G               +PG PG 
Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1197

Query: 411  RGLPGAHGPPGPTG---PKGEPGFTGRPGG------------PGVAGALGQKGDLGLPGQ 455
             G  G +GPPGP G   P G PG  GR GG            PG  G +G  G  G PG 
Sbjct: 1198 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1257

Query: 456  PGLRGPSGIPGLQG---------PAGPIGPQGLPGLKGEPG------------LPGPPGE 494
             GLRG  G  G QG         P GP+GP GLPGL+G+ G            L GPPGE
Sbjct: 1258 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1317

Query: 495  -GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGV-E 552
             G  G+ G  GP G PG  G  GI G  GP GP GPPG PG     G  G   P G   E
Sbjct: 1318 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1377

Query: 553  GAVLGKGGKP 562
              V G  G P
Sbjct: 1378 KGVQGPPGHP 1387



 Score =  430 bits (1105), Expect = e-120
 Identities = 259/561 (46%), Positives = 290/561 (51%), Gaps = 90/561 (16%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM----GKP 105
            GP GPP  +G      +P        KG+PGPPG PG  GP G  GFPG+ G+    G P
Sbjct: 839  GPPGPPGEQG------LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 892

Query: 106  GLHGQPGPAGPPG-FSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLP 164
            GL G  GP+GPPG     G+ G  G  G +GPPG+PG +G PG  G++G+ G  GP G  
Sbjct: 893  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 952

Query: 165  GPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-------------VG 211
            G  G+   G  G  G  GPPG  GE G +GE G PG +G KG+ G             VG
Sbjct: 953  GRDGVQ--GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1010

Query: 212  QPGLPGAPGQGGAPGPPGL---------------PGPAGL-GKPGLDGLPGAPGDKGESG 255
            QPG  GA G+ GA GP G                PGP GL G PG  G  G  GD G  G
Sbjct: 1011 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1070

Query: 256  PPGVPGPRGEPG---AVGPKGPPG-VDGVGVPGAAGLPGPQGPSGAKGEPGTRGP----- 306
            PPG PGPRG  G   A GP+GPPG V  +G PG  G PG  G  G +GEPG +GP     
Sbjct: 1071 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1130

Query: 307  -------------PGLIGPTG----------YGMPGLPGPKGDRGPAGVPGLLGDRGEPG 343
                         PG  GPTG           G PG PGP G+ GP G  G  GDRGE G
Sbjct: 1131 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG 1190

Query: 344  EDGEPGEQGPQGLGGPPG---LPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG 400
            E G+PG  GP G  GPPG     G AG PG  G  G KG  G  G  G PG  G  GP+G
Sbjct: 1191 EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1250

Query: 401  LAGKPGVPGERGLPGA---HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG 457
             AGKPG  G RGLPG+    G PG TG  G PG  G PG PG+ G  G KG+ G PG  G
Sbjct: 1251 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1310

Query: 458  LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPG---------PPG-EGRAGEPGTAGPTG 507
            L GP G  G +G  G  GPQG PG KGE G+PG         PPG  G AG  G  G TG
Sbjct: 1311 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG 1370

Query: 508  PPGVPGSPGITGPPGPPGPPG 528
            P G  G  G+ GPPG PGPPG
Sbjct: 1371 PGGPKGEKGVQGPPGHPGPPG 1391



 Score =  416 bits (1068), Expect = e-116
 Identities = 259/605 (42%), Positives = 299/605 (49%), Gaps = 87/605 (14%)

Query: 31  GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 90
           G  G  GY      +P   G  G P  +G+   L    P  P  L G PG  G+ G  G 
Sbjct: 380 GPPGPMGYTG----RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 435

Query: 91  PGPPGFPGKPGM-------GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLR 143
            G  G PG PG+       G PGL G+ G  G  G    G  GPPG  G+ G  G+ G R
Sbjct: 436 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG--AQGLPGPPGEDGERGDDGEIGPR 493

Query: 144 GEPGIRGDQGLRGPPGPPGLPGPSGIT-------IPGKPGAQGVPGPPGFQGEPGPQGEP 196
           G PG  G +GL GP GPPG+PGP G+          G  G QG PGPPG QG PG QG P
Sbjct: 494 GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 553

Query: 197 GPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAG-------------LGKP--- 239
           GP G  G  G+ G  G+PGLPG PG  G PG PG  GP G             LG P   
Sbjct: 554 GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 613

Query: 240 ---GLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSG 296
              G+DG+ G  G KGE G  G PG +G+ G  G +G      VGVPG+ G  GP+GP G
Sbjct: 614 GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE-----VGVPGSRGEDGPEGPKG 668

Query: 297 AKGEPGTRGPPGLIGPTG-------------------YGMPGLPGPKGDRGPAGVPGLLG 337
             G  G  GPPGL+G  G                    G PG PG  G++G  G+ G  G
Sbjct: 669 RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSG 728

Query: 338 DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
            RGE G  G  G++GP+G  G  G  G++G  G  GPPG +G  GP GP G PG +G  G
Sbjct: 729 PRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG 788

Query: 398 PSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG 457
           P G  G PG PG+RG  G  G  GP GP   PG  G  G  G  G +G++G  G PG PG
Sbjct: 789 PPGKDGLPGHPGQRGEVGFQGKTGPPGP---PGVVGPQGAAGETGPMGERGHPGPPGPPG 845

Query: 458 LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE----GRAGEP---GTAGPTGPPG 510
            +G  G  G +G  G  GP G PG  G  GL G PGE    G AG P   G  GP+GPPG
Sbjct: 846 EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 905

Query: 511 VPGSP------GITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGAV--LG 557
             GSP      G  GP GPPG PGP G PGA  E G+ G   P G     GV+G V   G
Sbjct: 906 PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 965

Query: 558 KGGKP 562
             G P
Sbjct: 966 PAGPP 970



 Score =  414 bits (1064), Expect = e-115
 Identities = 253/539 (46%), Positives = 277/539 (51%), Gaps = 55/539 (10%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG-MGKPGLH 108
            GP GPP          +P P     + G  GP G  GP+G PGPPG  G PG  G PG  
Sbjct: 506  GPKGPP---------GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 556

Query: 109  GQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG 168
            G  GP G  G    GK G PG+PG  GPPG PG  G PG +G+QG  GP GP G PGP G
Sbjct: 557  GAIGPHGEKG--PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 614

Query: 169  ITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGA--- 224
            +      G  G+ G  G +GE G  G PG  GD G+KGD G VG PG  G  G  G    
Sbjct: 615  VK-----GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR 669

Query: 225  ------PGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGV 277
                  PGPPGL G  G LG PGL G PG  G KG  G PG PG  GE GA G  G  G 
Sbjct: 670  TGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 729

Query: 278  DGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGL 335
             G  G  G  G  GP+G +G  G  GT G  G  GP G  G+PG  GP G  GP G PG 
Sbjct: 730  RGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP 789

Query: 336  LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP----- 390
             G  G PG  G+ GE G QG  GPPG PG  G  G  G  GP GE G  GPPG P     
Sbjct: 790  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 849

Query: 391  -------GIRGDQGPSGLAGKP------GVPGERGLPGAHGPPGPTGPKGEPGFTGRPGG 437
                   G +GD GP G  GK       G PGERGLPG  G PG  G +G  G  G  G 
Sbjct: 850  PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 909

Query: 438  PGVAGALGQKGDLGLPGQPGLRGP---SGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG- 493
            PG  GA G  G +G PG+PG +GP   +G  G+ G  GPIGP G  G++G  GLPGP G 
Sbjct: 910  PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 969

Query: 494  EGRAGEPGTAGPTGPP---GVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
             G AGE G  G  G P   G  G+ G  GPPGPPGP GP G PGA    G  G   P G
Sbjct: 970  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG 1028



 Score =  365 bits (938), Expect = e-101
 Identities = 233/578 (40%), Positives = 270/578 (46%), Gaps = 123/578 (21%)

Query: 82  PGKPGPRGPPGPPGFPGKPGMGKPGL--HGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQ 139
           P      GP G  G  G+P + +PG+   G PGP GP G               +GPPG 
Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL--------------IGPPG- 307

Query: 140 PGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGA---------------------- 177
             ++G PG  GD G RGPPG  GLPG  G   PG PG                       
Sbjct: 308 --IQGNPGPVGDPGERGPPGRAGLPGSDG--APGPPGTSLMLPFRFGSGGGDKGPVVAAQ 363

Query: 178 ---------------QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG----------VGQ 212
                          +G PGP G+ G PGP G+PG PG +G  GD G           G 
Sbjct: 364 EAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 423

Query: 213 PGLPGAPGQGGAPGPPGLPGPAGL-GKPGLDGLPGAPGDKGE---------SGPPGVPGP 262
           PG  G  G+ GA G  G+PG  G+ G  G DGLPG PG+KG           GPPG  G 
Sbjct: 424 PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 483

Query: 263 RGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGLP 321
           RG+ G +GP+G PG       G  GL GP+GP G  G PG RG  G  GP G  G  G P
Sbjct: 484 RGDDGEIGPRGLPGES-----GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP 538

Query: 322 GPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEA 381
           GP G +G  G  GL G +G  G  GE G QG  GL G PG  G  G PG+ GPPG KG  
Sbjct: 539 GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 598

Query: 382 GPGGP------------PGVPGIRGDQGPSGLAGKPGVP------------GERGLPGAH 417
           GP GP             GV GIRG +G  G  G+ G P            GE G+PG+ 
Sbjct: 599 GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR 658

Query: 418 GPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS---GIPGLQGPAGPI 474
           G  GP GPKG  G TG PG PG+ G  G+ G  GLPG PG +GP    G PG  G +G  
Sbjct: 659 GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 718

Query: 475 GPQGLPGLKGEPGLPGPPG----------EGRAGEPGTAGPTGPPGVPGSPGITGPPGPP 524
           G +GL G  G  G  GP G           G++G  GT+G  GP G PG  G+ GP GP 
Sbjct: 719 GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 778

Query: 525 GPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKP 562
           G PGP G PG   + G+ G   P    E    GK G P
Sbjct: 779 GFPGPKGPPGPPGKDGLPG--HPGQRGEVGFQGKTGPP 814


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  431 bits (1107), Expect = e-120
 Identities = 286/670 (42%), Positives = 320/670 (47%), Gaps = 155/670 (23%)

Query: 23   GPRASSG-GGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GPR ++G  GA G +G            GP GPP   G               L G  GP
Sbjct: 850  GPRGATGKSGAKGTSG----------GDGPHGPPGERG---------------LPGPQGP 884

Query: 82   PGKPGPRGPPGPPG---FPGKPGM-GKPGLHGQPGPAGPPGF----SRMGKAGPPGLPGK 133
             G PGP+GPPGPPG    PG PG  G+ G  G+ GP GPPG        G+ GP G  G 
Sbjct: 885  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944

Query: 134  VGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG---PSGIT-IPGKPGAQGVPGPPGFQGE 189
             GPPG PG +G PG  G +G +G PGPPG PG   P+G+   PG+ G  G  G PG +G 
Sbjct: 945  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004

Query: 190  PGPQGEPGP---PGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPG------------- 232
             GP G PGP   PG+RG  G  G +G PG PG  G  GA G  G+PG             
Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 1064

Query: 233  --PAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-VGVPGAAGL 288
              P GL G  G  G+ G  GDKGE G PG  G +G  G  GP GPPG  G VG PGAAG 
Sbjct: 1065 QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1124

Query: 289  PG------PQGPSGAKGEPGTRG---PPGLIG------PTG----------YGMPGLPGP 323
             G      PQG  GAKG+ GTRG   PPG IG      P+G           G PG PGP
Sbjct: 1125 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1184

Query: 324  KGDRGPAGV------PGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPG---------SAGL 368
            +G  GP G       PG +G+ G PGE GEPGE G  G+ G PG+ G          +G 
Sbjct: 1185 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1244

Query: 369  PGRRGPPGPKGEAGPGGPPGVPG---IRGDQGPSGLAG---------------KPGVPGE 410
            PG  GPPGPKG  G  GP G PG     GD GP G  G               +PG PG 
Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1304

Query: 411  RGLPGAHGPPGPTG---PKGEPGFTGRPGG------------PGVAGALGQKGDLGLPGQ 455
             G  G +GPPGP G   P G PG  GR GG            PG  G +G  G  G PG 
Sbjct: 1305 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1364

Query: 456  PGLRGPSGIPGLQG---------PAGPIGPQGLPGLKGEPG------------LPGPPGE 494
             GLRG  G  G QG         P GP+GP GLPGL+G+ G            L GPPGE
Sbjct: 1365 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1424

Query: 495  -GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGV-E 552
             G  G+ G  GP G PG  G  GI G  GP GP GPPG PG     G  G   P G   E
Sbjct: 1425 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1484

Query: 553  GAVLGKGGKP 562
              V G  G P
Sbjct: 1485 KGVQGPPGHP 1494



 Score =  430 bits (1105), Expect = e-120
 Identities = 259/561 (46%), Positives = 290/561 (51%), Gaps = 90/561 (16%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM----GKP 105
            GP GPP  +G      +P        KG+PGPPG PG  GP G  GFPG+ G+    G P
Sbjct: 946  GPPGPPGEQG------LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 999

Query: 106  GLHGQPGPAGPPG-FSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLP 164
            GL G  GP+GPPG     G+ G  G  G +GPPG+PG +G PG  G++G+ G  GP G  
Sbjct: 1000 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 1059

Query: 165  GPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-------------VG 211
            G  G+   G  G  G  GPPG  GE G +GE G PG +G KG+ G             VG
Sbjct: 1060 GRDGVQ--GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1117

Query: 212  QPGLPGAPGQGGAPGPPGL---------------PGPAGL-GKPGLDGLPGAPGDKGESG 255
            QPG  GA G+ GA GP G                PGP GL G PG  G  G  GD G  G
Sbjct: 1118 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1177

Query: 256  PPGVPGPRGEPG---AVGPKGPPG-VDGVGVPGAAGLPGPQGPSGAKGEPGTRGP----- 306
            PPG PGPRG  G   A GP+GPPG V  +G PG  G PG  G  G +GEPG +GP     
Sbjct: 1178 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1237

Query: 307  -------------PGLIGPTG----------YGMPGLPGPKGDRGPAGVPGLLGDRGEPG 343
                         PG  GPTG           G PG PGP G+ GP G  G  GDRGE G
Sbjct: 1238 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG 1297

Query: 344  EDGEPGEQGPQGLGGPPG---LPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG 400
            E G+PG  GP G  GPPG     G AG PG  G  G KG  G  G  G PG  G  GP+G
Sbjct: 1298 EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1357

Query: 401  LAGKPGVPGERGLPGA---HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG 457
             AGKPG  G RGLPG+    G PG TG  G PG  G PG PG+ G  G KG+ G PG  G
Sbjct: 1358 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1417

Query: 458  LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPG---------PPG-EGRAGEPGTAGPTG 507
            L GP G  G +G  G  GPQG PG KGE G+PG         PPG  G AG  G  G TG
Sbjct: 1418 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG 1477

Query: 508  PPGVPGSPGITGPPGPPGPPG 528
            P G  G  G+ GPPG PGPPG
Sbjct: 1478 PGGPKGEKGVQGPPGHPGPPG 1498



 Score =  416 bits (1068), Expect = e-116
 Identities = 259/605 (42%), Positives = 299/605 (49%), Gaps = 87/605 (14%)

Query: 31   GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 90
            G  G  GY      +P   G  G P  +G+   L    P  P  L G PG  G+ G  G 
Sbjct: 487  GPPGPMGYTG----RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 542

Query: 91   PGPPGFPGKPGM-------GKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLR 143
             G  G PG PG+       G PGL G+ G  G  G    G  GPPG  G+ G  G+ G R
Sbjct: 543  DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG--AQGLPGPPGEDGERGDDGEIGPR 600

Query: 144  GEPGIRGDQGLRGPPGPPGLPGPSGIT-------IPGKPGAQGVPGPPGFQGEPGPQGEP 196
            G PG  G +GL GP GPPG+PGP G+          G  G QG PGPPG QG PG QG P
Sbjct: 601  GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 660

Query: 197  GPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAG-------------LGKP--- 239
            GP G  G  G+ G  G+PGLPG PG  G PG PG  GP G             LG P   
Sbjct: 661  GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720

Query: 240  ---GLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSG 296
               G+DG+ G  G KGE G  G PG +G+ G  G +G      VGVPG+ G  GP+GP G
Sbjct: 721  GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE-----VGVPGSRGEDGPEGPKG 775

Query: 297  AKGEPGTRGPPGLIGPTG-------------------YGMPGLPGPKGDRGPAGVPGLLG 337
              G  G  GPPGL+G  G                    G PG PG  G++G  G+ G  G
Sbjct: 776  RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSG 835

Query: 338  DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
             RGE G  G  G++GP+G  G  G  G++G  G  GPPG +G  GP GP G PG +G  G
Sbjct: 836  PRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG 895

Query: 398  PSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG 457
            P G  G PG PG+RG  G  G  GP GP   PG  G  G  G  G +G++G  G PG PG
Sbjct: 896  PPGKDGLPGHPGQRGEVGFQGKTGPPGP---PGVVGPQGAAGETGPMGERGHPGPPGPPG 952

Query: 458  LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE----GRAGEP---GTAGPTGPPG 510
             +G  G  G +G  G  GP G PG  G  GL G PGE    G AG P   G  GP+GPPG
Sbjct: 953  EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 1012

Query: 511  VPGSP------GITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGAV--LG 557
              GSP      G  GP GPPG PGP G PGA  E G+ G   P G     GV+G V   G
Sbjct: 1013 PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 1072

Query: 558  KGGKP 562
              G P
Sbjct: 1073 PAGPP 1077



 Score =  414 bits (1064), Expect = e-115
 Identities = 253/539 (46%), Positives = 277/539 (51%), Gaps = 55/539 (10%)

Query: 50   GPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG-MGKPGLH 108
            GP GPP          +P P     + G  GP G  GP+G PGPPG  G PG  G PG  
Sbjct: 613  GPKGPP---------GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 663

Query: 109  GQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG 168
            G  GP G  G    GK G PG+PG  GPPG PG  G PG +G+QG  GP GP G PGP G
Sbjct: 664  GAIGPHGEKG--PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 721

Query: 169  ITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGA--- 224
            +      G  G+ G  G +GE G  G PG  GD G+KGD G VG PG  G  G  G    
Sbjct: 722  VK-----GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGR 776

Query: 225  ------PGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGV 277
                  PGPPGL G  G LG PGL G PG  G KG  G PG PG  GE GA G  G  G 
Sbjct: 777  TGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 836

Query: 278  DGV-GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGL 335
             G  G  G  G  GP+G +G  G  GT G  G  GP G  G+PG  GP G  GP G PG 
Sbjct: 837  RGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP 896

Query: 336  LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP----- 390
             G  G PG  G+ GE G QG  GPPG PG  G  G  G  GP GE G  GPPG P     
Sbjct: 897  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 956

Query: 391  -------GIRGDQGPSGLAGKP------GVPGERGLPGAHGPPGPTGPKGEPGFTGRPGG 437
                   G +GD GP G  GK       G PGERGLPG  G PG  G +G  G  G  G 
Sbjct: 957  PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 1016

Query: 438  PGVAGALGQKGDLGLPGQPGLRGP---SGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG- 493
            PG  GA G  G +G PG+PG +GP   +G  G+ G  GPIGP G  G++G  GLPGP G 
Sbjct: 1017 PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 1076

Query: 494  EGRAGEPGTAGPTGPP---GVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
             G AGE G  G  G P   G  G+ G  GPPGPPGP GP G PGA    G  G   P G
Sbjct: 1077 PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG 1135



 Score =  364 bits (935), Expect = e-100
 Identities = 232/571 (40%), Positives = 269/571 (47%), Gaps = 123/571 (21%)

Query: 89  GPPGPPGFPGKPGMGKPGL--HGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEP 146
           GP G  G  G+P + +PG+   G PGP GP G               +GPPG   ++G P
Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL--------------IGPPG---IQGNP 419

Query: 147 GIRGDQGLRGPPGPPGLPGPSGITIPGKPGA----------------------------- 177
           G  GD G RGPPG  GLPG  G   PG PG                              
Sbjct: 420 GPVGDPGERGPPGRAGLPGSDG--APGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI 477

Query: 178 --------QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG----------VGQPGLPGAP 219
                   +G PGP G+ G PGP G+PG PG +G  GD G           G PG  G  
Sbjct: 478 LQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR 537

Query: 220 GQGGAPGPPGLPGPAGL-GKPGLDGLPGAPGDKGE---------SGPPGVPGPRGEPGAV 269
           G+ GA G  G+PG  G+ G  G DGLPG PG+KG           GPPG  G RG+ G +
Sbjct: 538 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 597

Query: 270 GPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGLPGPKGDRG 328
           GP+G PG       G  GL GP+GP G  G PG RG  G  GP G  G  G PGP G +G
Sbjct: 598 GPRGLPGES-----GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 652

Query: 329 PAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGP-- 386
             G  GL G +G  G  GE G QG  GL G PG  G  G PG+ GPPG KG  GP GP  
Sbjct: 653 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712

Query: 387 ----------PGVPGIRGDQGPSGLAGKPGVP------------GERGLPGAHGPPGPTG 424
                      GV GIRG +G  G  G+ G P            GE G+PG+ G  GP G
Sbjct: 713 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 772

Query: 425 PKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS---GIPGLQGPAGPIGPQGLPG 481
           PKG  G TG PG PG+ G  G+ G  GLPG PG +GP    G PG  G +G  G +GL G
Sbjct: 773 PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG 832

Query: 482 LKGEPGLPGPPG----------EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG 531
             G  G  GP G           G++G  GT+G  GP G PG  G+ GP GP G PGP G
Sbjct: 833 KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG 892

Query: 532 APGAFDETGIAGLHLPNGGVEGAVLGKGGKP 562
            PG   + G+ G   P    E    GK G P
Sbjct: 893 PPGPPGKDGLPG--HPGQRGEVGFQGKTGPP 921


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  431 bits (1107), Expect = e-120
 Identities = 259/575 (45%), Positives = 300/575 (52%), Gaps = 69/575 (12%)

Query: 31   GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 90
            G+ GA GY P +   P   GPVG P  +G   Y+ +P         GE G PG PG RG 
Sbjct: 730  GSPGAKGY-PGRQGLP---GPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK 785

Query: 91   PGPPGFPG------KPGM-GKPGLHGQPGPAGPPGF-SRMGKAGPPGLPGKVGPPGQPGL 142
             G PGFPG       PG+ G PG  G PGP G PG    +G  GP G PG  G  G  G 
Sbjct: 786  MGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGS 845

Query: 143  RGEPGIRGDQGLRGPPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQGEPGPQGEPGP 198
             GEPG++GD+G +G PG  G PG  G      +PG PGA+G PGP G  G+ G  G PGP
Sbjct: 846  VGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGP 905

Query: 199  PGDRGLKGDNGV----GQPGLPGAPGQGGAPGPPGLPGPAG----LGKPGLDGLPGAPGD 250
            PG  G  GD G     G  G+ G PG  G PGP G  GP G    +G PG  GL G PG 
Sbjct: 906  PGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGR 965

Query: 251  KGESGPPGVPGPRGEPGAVGPKGPPGVDG----VGVPGAAGLPGPQGPSGAKGEPGTRGP 306
            KG  G PG+ G +GEPG  G  GP G  G    +G+ G  G+ G +G  G  G PG  GP
Sbjct: 966  KGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGP 1025

Query: 307  PGLIG----PTGYGMPGLPGPKG---DRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGP 359
             G +G    P G G PG PGP+G    RGP G+ G  G RG  G DG  GEQG +GL GP
Sbjct: 1026 KGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGP 1085

Query: 360  PGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGP 419
            PG  G  G PG++G  G +G  G  G PG+PG     GP G  G PG PG +G  G  GP
Sbjct: 1086 PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPG---PSGPPGTKGLPGEPGPQGPQGPIGP 1142

Query: 420  PGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGL 479
            PG  GPKG PG  G PG PG AG  G  G LG PG+ GL G  G PGL+G +GP+GP GL
Sbjct: 1143 PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGL 1202

Query: 480  PGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVP-------------------------- 512
             G +G+PG  G  GE G+ G  G  GP GPPGV                           
Sbjct: 1203 KGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY 1262

Query: 513  ----GSPGITGPPGPPGPPGPPGAPGAFDETGIAG 543
                G  G+ G PGPPG PGP G+ G+   TG  G
Sbjct: 1263 QGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPG 1297



 Score =  423 bits (1088), Expect = e-118
 Identities = 262/566 (46%), Positives = 306/566 (54%), Gaps = 48/566 (8%)

Query: 12   LLLLLVLVLGCGPR-ASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPL 70
            L+L     L   PR  SSG      AG  P     P+  GP GP     KG   +  LP 
Sbjct: 590  LVLAPAQFLSSSPRPTSSGYSIFHLAGSTPF----PLLMGPPGP-----KG---DCGLPG 637

Query: 71   LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAG-PPGFSR---MGKAG 126
             P  L G PG PG  GPRGPPGP G PG P  G PG  GQ G  G  PG +     G  G
Sbjct: 638  -PPGLPGLPGIPGARGPRGPPGPYGNPGLP--GPPGAKGQKGDPGLSPGKAHDGAKGDMG 694

Query: 127  PPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGF 186
             PGL G  GPPG+ G +G PG  G  G +G PGP G PG  G      PG QG+PGP G 
Sbjct: 695  LPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGY-----PGRQGLPGPVGD 749

Query: 187  QGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLP 245
             G  G +G  G PG  GL G +  G+ GLPG PG+ G  G PG PG  G  G PGLD   
Sbjct: 750  PGPKGSRGYIGLPGLFGLPGSD--GERGLPGVPGKRGKMGMPGFPGVFGERGPPGLD--- 804

Query: 246  GAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGTR 304
            G PG+ G  GPPGVPG  G+ G +GP G PG  G+ G+ G+ G PG +G  G +G PG  
Sbjct: 805  GNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVS 864

Query: 305  GPPGLIGPTG-YGMPGLPGPKGDRGP---AGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP 360
            G PG  G  G  G+PG PG +G  GP    G  G +G  G PG +G PG+ GP G  GP 
Sbjct: 865  GDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPE 924

Query: 361  GL---PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAH 417
            G+   PG+ GLPG RG  GP+G+ GP GPPG PG+ G  G  G  G+PG+ G +G PG  
Sbjct: 925  GMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDP 984

Query: 418  GPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQ 477
            G PGP G +G  GF G  G PG+   +G+KGD G+ G PG+ GP G  G  G  G +G  
Sbjct: 985  GRPGPVGEQGFMGFIGLVGEPGI---VGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTP 1041

Query: 478  GLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAF 536
            G PG +G PG  GPPG  G  G  G  GP GP G  GS G+ GPPGP G PG PG  G  
Sbjct: 1042 GEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVA 1101

Query: 537  DETGIAGLHLPNGGVEGAVLGKGGKP 562
             E G    HL + G  G + G  G P
Sbjct: 1102 GERG----HLGSRGFPG-IPGPSGPP 1122



 Score =  409 bits (1050), Expect = e-114
 Identities = 258/591 (43%), Positives = 297/591 (50%), Gaps = 62/591 (10%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GP+ S G  G  G  G        P + GP GPP   G            P    G  G 
Sbjct: 1024 GPKGSMGHPGMPGGMG-------TPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGE 1076

Query: 82   PGKPGPRGPPGPPGFPGKPG----------MGKPGLHGQPGPAGPPGFSRM-------GK 124
             G  G +GPPGP G PG+PG          +G  G  G PGP+GPPG   +       G 
Sbjct: 1077 QGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGP 1136

Query: 125  AGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSG-ITIPGKPGAQGVPGP 183
             GP G PG++GP G PG  GEPG+ G+ G++G  GP G PG  G I   G+PG +G  GP
Sbjct: 1137 QGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGP 1196

Query: 184  PGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAG------- 235
             G  G  G +G+PGP G+ G KG  G+ G+ G PG PG  G  GP G  G  G       
Sbjct: 1197 MGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGA 1256

Query: 236  LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGP 294
             G  G  G  G  G  G+ GPPG PGP+G  G++GP G PG  G  G PG AG  G +G 
Sbjct: 1257 KGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGI 1316

Query: 295  SGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQ 354
             G  G PG +G  G  G  G    G PGP GDRGP G  G   DRGEPG+ G PG++G Q
Sbjct: 1317 VGPLGPPGPKGEKGEQGEDGKA-EGPPGPPGDRGPVGDRG---DRGEPGDPGYPGQEGVQ 1372

Query: 355  GLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGP------PGVPGIRGDQGPSGLAGKPGVP 408
            GL G PG  G  G PG RG PGPKG  G  GP       G PG RG QG  GL G  GV 
Sbjct: 1373 GLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVV 1432

Query: 409  GERGLPGAHGP------PGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLP---GQPGLR 459
            G +GL G  GP       G  G +GE G  G PG  G AG  G  G  GLP   G PG +
Sbjct: 1433 GRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFK 1492

Query: 460  GPSGIPGLQGPAGPIGPQ---GLPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSP 515
            G SG+PG  GP G  G +   GLPG +GEPG  G PG+ G  G PG AG  GP G PG  
Sbjct: 1493 GESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDI 1552

Query: 516  GITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGL 566
            G  G  GP GPPG  G  G     GI G      G+ G    KG +  +GL
Sbjct: 1553 GFKGIQGPRGPPGLMGKEGIVGPLGILG----PSGLPGPKGDKGSRGDWGL 1599



 Score =  343 bits (881), Expect = 2e-94
 Identities = 215/501 (42%), Positives = 247/501 (49%), Gaps = 76/501 (15%)

Query: 49   KGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM----GK 104
            +GP+GPP   G         P  P    GEPG PG+ G +G  GP G PG+ G+    G+
Sbjct: 1137 QGPIGPPGEMG---------PKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGE 1187

Query: 105  PGLHGQPGPAGPPGFSR-------------------MGKAGPPGLPGKVG---PPGQPGL 142
            PGL G  GP GP G                      MG+ GPPG PG  G   P G+ G 
Sbjct: 1188 PGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGK 1247

Query: 143  RGEPGIRG------------DQGLRGPPGPPGLPGPSGIT-------IPGKPGAQGVPGP 183
            +GE G  G            + G+ G PGPPG PGP G          PG+ GAQG PG 
Sbjct: 1248 QGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGL 1307

Query: 184  PGFQGEPG---PQGEPGPPGDRGLKGDNGV--GQPGLPGAPG------QGGAPGPPGLPG 232
             G+ G  G   P G PGP G++G +G++G   G PG PG  G        G PG PG PG
Sbjct: 1308 AGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPG 1367

Query: 233  PAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV----GVPGAAGL 288
              G+   GL G PG  G  G  GP G PGP+G  GA GPKG  G  G     GV G  GL
Sbjct: 1368 QEGV--QGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGL 1425

Query: 289  PGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEP 348
            PGP+G  G +G  G  GP GL G  G    G  G +GD G  G  G  G RG PG  G P
Sbjct: 1426 PGPRGVVGRQGLEGIAGPDGLPGRDGQA--GQQGEQGDDGDPGPMGPAGKRGNPGVAGLP 1483

Query: 349  GEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVP 408
            G QGP G  G  GLPG  G PG+RG  G  G  G  G PG  G  GD G  G  G  G+ 
Sbjct: 1484 GAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLF 1543

Query: 409  GERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQ 468
            G +G PG  G  G  GP+G PG  G+    G+ G LG  G  GLPG  G +G  G  GLQ
Sbjct: 1544 GPKGPPGDIGFKGIQGPRGPPGLMGK---EGIVGPLGILGPSGLPGPKGDKGSRGDWGLQ 1600

Query: 469  GPAGPIGPQGLPGLKGEPGLP 489
            GP GP GP+G PG  G PG P
Sbjct: 1601 GPRGPPGPRGRPGPPGPPGGP 1621



 Score =  276 bits (706), Expect = 5e-74
 Identities = 211/578 (36%), Positives = 249/578 (43%), Gaps = 109/578 (18%)

Query: 75  LKGEPGPPGKPGPRGPPGPP--------------------GFPGKPGMGKPGLHGQP--- 111
           ++  PG P  P P   P PP                        KP   +   H  P   
Sbjct: 426 IQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFT 485

Query: 112 ----GPAGPPGFSRM------------GKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLR 155
                PA  PG +R             G + P   P    P   P    +P         
Sbjct: 486 ALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKA 545

Query: 156 GPPGPPGLPGPSGITIPGKPGAQGVP------GPPGFQGEPGPQGEPG------------ 197
           GP   P  P P     PGK  A+ VP       P   Q +P  Q  P             
Sbjct: 546 GPKSSPRKPVPLR---PGK-AARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSS 601

Query: 198 -PPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGP 256
             P   G    +  G    P   G  G  G  GLPGP GL  PGL G+PGA G +G  GP
Sbjct: 602 PRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGL--PGLPGIPGARGPRGPPGP 659

Query: 257 PGVPGPRGEPGAVGPKGPPGV------DG----VGVPGAAGLPGPQGPSGAKGEPGTRGP 306
            G PG  G PGA G KG PG+      DG    +G+PG +G PGP G  G KG PG  G 
Sbjct: 660 YGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGH 719

Query: 307 PGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSA 366
           PG          G PGP+G  G  G PG    +G PG  G+PG +G +G  G PGL G  
Sbjct: 720 PG--------EQGQPGPEGSPGAKGYPGR---QGLPGPVGDPGPKGSRGYIGLPGLFGLP 768

Query: 367 GLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKP---GVPGERGLP------GAH 417
           G  G RG PG  G+ G  G PG PG+ G++GP GL G P   G+PG  G+P      G  
Sbjct: 769 GSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVL 828

Query: 418 GPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGL---RGPSGIPGLQGPAGPI 474
           GP G  GPKG  G  G  G PG+ G  G++G  G+ G PG    +G  G+PG  G  G  
Sbjct: 829 GPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKP 888

Query: 475 GPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGP---------P 524
           GP G  G KG  G PGPPG EG  G+ G  G  GP G+ G PG  G PGP          
Sbjct: 889 GPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDE 948

Query: 525 GPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKP 562
           GP GPPGAPG   + G  G      G++G V G+ G P
Sbjct: 949 GPMGPPGAPGLEGQPGRKGFP-GRPGLDG-VKGEPGDP 984



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 59/233 (25%), Positives = 77/233 (33%), Gaps = 19/233 (8%)

Query: 363 PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQ--GPSGLAGKPGVPGERGLPGAHGPP 420
           P    LP  RGP G    A P  P         Q     G A  P +P +     A  P 
Sbjct: 277 PALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPM 336

Query: 421 GPTGPKGEPGFTGRPGGPGVAGAL-GQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGL 479
            P    G    T RP     +  +   K    LP +P     S +P ++ P      +  
Sbjct: 337 LPASVGGSTR-TPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVP-IKSPHPT--QKTA 392

Query: 480 PGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVP--GSPGITGPPGPPGPPGPPGAPGAFD 537
           P    +  LP          P  A  + P   P   +PG+  PP P   P PP       
Sbjct: 393 PSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPP------- 445

Query: 538 ETGIAGLHLPN-GGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASG 589
            T  +   +P     E  +     KP       S H  P FTA+ +SP P  G
Sbjct: 446 TTSSSKKPIPTLARTEAKITSHASKP--ASARTSTHKPPPFTALSSSPAPTPG 496


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  426 bits (1095), Expect = e-119
 Identities = 261/620 (42%), Positives = 292/620 (47%), Gaps = 126/620 (20%)

Query: 46  PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG---- 101
           P   GP GPP + G+              + GE GPPG PGP GP G PG PGKPG    
Sbjct: 31  PGPPGPPGPPGKPGQD------------GIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGL 78

Query: 102 ------------------MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLR 143
                              G PG  G  GP GPPG    G  GPPG  G  GPPG  GLR
Sbjct: 79  PGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLR 138

Query: 144 GEPGIRGDQGLRGPPGPPGLPGPSGITIPGK----------PGAQGVPGPPGFQGEPGPQ 193
           G PG  G  GL GPPGPPG PG  G+   G           PG  G PG PGF+G  G +
Sbjct: 139 GPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYK 198

Query: 194 GEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAG----------LGKPGLD 242
           GE G  G  G KGD G  G  GLPG+ G  G  G  GLPGP G           G PG+ 
Sbjct: 199 GEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIP 258

Query: 243 GLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPG 302
           G PG  GD+GE GP G  GP+G+ G  GPKG PGV            GP G  G  G+ G
Sbjct: 259 GAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGV-----------AGPSGEPGMPGKDG 307

Query: 303 TRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPG 361
             G PGL G  G  G  G PG KG  G  G+PG  G +GE GE G  GE G  G  G PG
Sbjct: 308 QNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPG 367

Query: 362 LPGSAGLPGRRGPPGPKGEAG---PGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA-- 416
           +PG AG+PG RG  G +G AG   P GPPG PG+RG QG  G  G PG+PG +GL G   
Sbjct: 368 VPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVG 427

Query: 417 -HGPPGPTGPKGEPGFTGRPGGPGVAGALG------------QKGDLGLPGQPGLRGPSG 463
             GP G  GPKG+ G  G  G PG  G LG             +G+LG  G  G  G SG
Sbjct: 428 DRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSG 487

Query: 464 IPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE----------------------------- 494
           + G+ GP GP+G QG+PG+ G  G PG PG+                             
Sbjct: 488 VQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKP 547

Query: 495 ---GRAGEPGTAGPTGPPGVPGS---------PGITGPPGPPGPPGPPGAPGAFDETGIA 542
              G  G PG AGP GPPG PGS         PG  GP G  G PGP G  G   + G A
Sbjct: 548 LAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAA 607

Query: 543 GLHLPNGGVEGAVLGKGGKP 562
           G  L     +    G  G P
Sbjct: 608 GAGLDGPEGDQGPQGPQGVP 627



 Score =  377 bits (967), Expect = e-104
 Identities = 240/577 (41%), Positives = 274/577 (47%), Gaps = 97/577 (16%)

Query: 118 GFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGA 177
           G  R+G  GPPG PG  G PGQ G+ GE    G  GL GPPGP G PG      PGKPG 
Sbjct: 24  GAQRVGLPGPPGPPGPPGKPGQDGIDGE---AGPPGLPGPPGPKGAPGK-----PGKPGE 75

Query: 178 QGVPGPPGF------QGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPP--- 228
            G+PG PG        G PGP+G PG  G  G  G  G+G  GLPG PG+ G  GPP   
Sbjct: 76  AGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135

Query: 229 ---GLPGPAGLGKPGLDGLPGAPGDKGESG---------------PPGVPGPRGEPGAVG 270
              G PGP+GL  PGL G PG PG  G  G               PPG PGP G PG  G
Sbjct: 136 GLRGPPGPSGL--PGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKG 193

Query: 271 PKGPPGVDG----------VGVPGAAGLPGP---QGPSGAKGEPGTRGPPGLIGPTGY-- 315
           P G  G  G           G PG AGLPG    QGP G +G PG  GPPG  GP G+  
Sbjct: 194 PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRG 253

Query: 316 --GMPGLPGPKGDR------------------GPAGVPGLLGDRGEPGEDGEPGEQGPQG 355
             G+PG PG  GDR                  GP G PG+ G  GEPG  G+ G+ G  G
Sbjct: 254 PPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPG 313

Query: 356 LGGPPGLPGSAGLPGRRGP---PGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERG 412
           L G  G  G  G PG +GP   PG  G AG  G  G  G  G+ G +G +G+PGVPG+ G
Sbjct: 314 LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373

Query: 413 LPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAG 472
           +PG  G  G  G  G  G  G PG PGV G  GQKG +G PG PG +G  G  G +GP G
Sbjct: 374 MPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGG 433

Query: 473 PIGPQGLPGLKGEPGLPGPPGE-------GRAGEPGTAGPTGPPGVPGSPGITGPPGPPG 525
             GP+G  G+ G  GLPG  GE       G  GE G+ G  GP G  G  G +G  G PG
Sbjct: 434 AAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPG 493

Query: 526 PPGP------PGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAH-ATPAFT 578
           PPGP      PG PG   + G+ G       +       GG     + +L+AH   P   
Sbjct: 494 PPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELC---GGMISEQIAQLAAHLRKPLAP 550

Query: 579 AVLTSPFPAS-----GMPVKFDRTLYNGHSGYNPATG 610
             +  P PA      G P         G  GY   TG
Sbjct: 551 GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTG 587



 Score =  320 bits (820), Expect = 3e-87
 Identities = 213/499 (42%), Positives = 237/499 (47%), Gaps = 102/499 (20%)

Query: 50  GPVGPPFREG-KGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG----MGK 104
           GP GPP   G KG          P   KGE G  GK G +G PGPPG  G PG     G 
Sbjct: 181 GPPGPPGMPGFKG----------PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP 230

Query: 105 PGLHGQPGPAGPPGF-SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP--- 160
            GL G PGP GPPG    +G  GPPG+PG  G  G  G RG  G RG +G  G PGP   
Sbjct: 231 RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT 290

Query: 161 PGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPG---------PQGEPGPPGDRGLKGDNG- 209
           PG+ GPSG   +PGK G  GVPG  G +GE G         P G PG PG  G KG+ G 
Sbjct: 291 PGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGE 350

Query: 210 ---------VGQPGLPGAPGQGGAPGPPGLPGPAGL-------GKPGLDGLPGAPGDKGE 253
                     G  G PG PG  G PG  G  G  G        G PG  G+ G  G KG 
Sbjct: 351 RGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGS 410

Query: 254 SGPPGVPGP---------RGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKGEPGT 303
            G PG+PGP         RG  GA GPKG  G+ G  G+PG  G  GP G  G KGE G+
Sbjct: 411 MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGS 470

Query: 304 RG---PPGLIGPTG----YGMPGLPGPKGDRGPAGVPGLLGDRGEPGED----------- 345
           RG   P G  GP G     G+PG PGP G +G  GVPG+ G  G PG++           
Sbjct: 471 RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG 530

Query: 346 --------------------GEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385
                               G  G  GP G  GPPG PGS G PG RGPPG +G  G  G
Sbjct: 531 GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELG 590

Query: 386 PPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALG 445
            PG  G +GD+G  G AG        GL G  G  GP GP+G PG T + G  G  G  G
Sbjct: 591 DPGPRGNQGDRGDKGAAG-------AGLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPG 642

Query: 446 QKGDLGLPGQPGLRGPSGI 464
             GD GLPG  G +G  GI
Sbjct: 643 PPGDPGLPGAIGAQGTPGI 661



 Score =  220 bits (561), Expect = 3e-57
 Identities = 139/313 (44%), Positives = 151/313 (48%), Gaps = 62/313 (19%)

Query: 309 LIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGL 368
           L+   G    GLPGP G  GP G PG  G  GE G  G PG  GP+G  G PG PG AGL
Sbjct: 19  LLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGL 78

Query: 369 P---------GRRGPPGPK--------------------------GEAGPGGPPGVPGIR 393
           P         GR GPPGPK                          GEAG  GPPG  G+R
Sbjct: 79  PGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLR 138

Query: 394 GDQGPSGLAGKPGVPGERGLPGAHG---------------PPGPTGPKGEPGF---TGRP 435
           G  GPSGL G PG PG  G PG  G               PPGP GP G PGF   TG  
Sbjct: 139 GPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYK 198

Query: 436 GGPGVAGALGQKGD------LGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLP 489
           G  G  G  G+KGD       GLPG  GL+GP G+ GL GP GP G +G  G +G PG+P
Sbjct: 199 GEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIP 258

Query: 490 GPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPN 548
           G PG+ G  GE G  G  GP G  G PG  G PG  GP G PG PG   + G+ GL    
Sbjct: 259 GAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQK 318

Query: 549 G--GVEGAVLGKG 559
           G  G  GA   KG
Sbjct: 319 GEAGRNGAPGEKG 331



 Score =  211 bits (536), Expect = 2e-54
 Identities = 155/431 (35%), Positives = 172/431 (39%), Gaps = 141/431 (32%)

Query: 31  GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 90
           G  G  G AP K     ++GP G  FR  KG               G PGP G PG  GP
Sbjct: 253 GPPGIPG-APGKAGDRGERGPEG--FRGPKGDL-------------GRPGPKGTPGVAGP 296

Query: 91  PGPPGFPGKPGM-GKPGLHGQ---------PGPAGPPGF-------------------SR 121
            G PG PGK G  G PGL GQ         PG  GP G                      
Sbjct: 297 SGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGE 356

Query: 122 MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVP 181
           +G+AGP G PG  G  G PG RGE G RG  G  GP GPPG PG  G    G+ G+ G P
Sbjct: 357 LGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQ--GQKGSMGDP 414

Query: 182 GPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGL----- 236
           G PG QG  G  G+ GP G  G KGD G+   G  G PG  G  GP GL GP G      
Sbjct: 415 GLPGPQGLRGDVGDRGPGGAAGPKGDQGIA--GSDGLPGDKGELGPSGLVGPKGESGSRG 472

Query: 237 -----------GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKG------------ 273
                      G  G+ G+PG PG  G  G PGVPG  G+PG  G +             
Sbjct: 473 ELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGM 532

Query: 274 --------------PPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY---- 315
                         P     +G PG AG PGP GP G+ G PG RGPPG  GPTG     
Sbjct: 533 ISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDP 592

Query: 316 -------------------------------------------GMPGLPGPKGDRGPAGV 332
                                                      G PG PGP GD    G+
Sbjct: 593 GPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD---PGL 649

Query: 333 PGLLGDRGEPG 343
           PG +G +G PG
Sbjct: 650 PGAIGAQGTPG 660



 Score =  153 bits (387), Expect = 5e-37
 Identities = 111/309 (35%), Positives = 135/309 (43%), Gaps = 77/309 (24%)

Query: 50  GPVGPPFREG----KGQYLEMPLPLLP--MDLKGEPGPPGKPGPRGPPGPPGFPGKPGM- 102
           GP GPP   G    +GQ   M  P LP    L+G+ G  G  G  GP G  G  G  G+ 
Sbjct: 391 GPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLP 450

Query: 103 ---------------GKPGLHGQPGPAG---PPGFSRM-GKAGPPGLPGKVGPPGQPGLR 143
                          G+ G  G+ GP G   P G S + G  GPPG  G  G PG PG+ 
Sbjct: 451 GDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGIT 510

Query: 144 GEPGIRGDQ----------------------------------GLRGPPGPPGLPGPSGI 169
           G+PG+ G +                                  G  GP GPPG PGP   
Sbjct: 511 GKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGP--- 567

Query: 170 TIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPG 229
             PG  G  G  GPPG++G  G  G+PGP G++G +GD G    GL G  G  G  GP G
Sbjct: 568 --PGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQG 625

Query: 230 LPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLP 289
           +PG +   K G DG PG P      GPPG P   G PGA+G +G PG+        A L 
Sbjct: 626 VPGTS---KDGQDGAPGEP------GPPGDP---GLPGAIGAQGTPGICDTSACQGAVLG 673

Query: 290 GPQGPSGAK 298
           G    SG++
Sbjct: 674 GVGEKSGSR 682


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  424 bits (1089), Expect = e-118
 Identities = 273/618 (44%), Positives = 309/618 (50%), Gaps = 119/618 (19%)

Query: 67   PLPLL-PMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP----------GLHGQPGPAG 115
            P P+  P   KGEPG  G  G  GPPG PG PG+ G   P          G  G PG  G
Sbjct: 1246 PCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADG 1305

Query: 116  PPGF-SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPG-LPGPSGITIPG 173
             PG   R G  G PG PG  G PG PG RG+PG RG +G +G PG PG + G  G  +PG
Sbjct: 1306 RPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPG 1365

Query: 174  K---PGAQGVPGPPGFQGEPGPQGEPGPP--------GDRGLKGDNGVGQ----PGLPGA 218
            +   PG  G PGP G  G+PGP+G PG P        GDRG +G  G G+    PG PG 
Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGL 1425

Query: 219  PGQGGAPGPPGLPGPAGL---------GKPGLDGLPGAPGDKGESGPPGV---------P 260
            PG  G+PGP G  GP G          G PGL G PG+PG++G  GPPG          P
Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485

Query: 261  GPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGP---------SGAKGEPGTRGPPGLI 310
            GP GE G  G +GPPG  G  G+PG AG PG +GP          G KGEPG  G P ++
Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545

Query: 311  GPTGYGMPGLPGPKGDRGPAGVPGLLGDR--------GEPGEDGEPGEQGPQGL---GGP 359
            GP   G  G  G  G  GP G  G+ G+R        G+PG  G+PG++GP GL    GP
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605

Query: 360  P---GLPGSAGLPGRRGPPGP---------KGEAGPGGPPGVPGIRGDQGPSGLAGKPGV 407
            P   G PG  G PGR GPPGP          GE G  GPPG PG+ G  G  GL G PGV
Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665

Query: 408  ------------PGERGLPGAHGPPGPTGPKGEPGFTGRPG-----GPGV---------- 440
                        PGE G  G+ G  GP G +GEPG  G PG     GPG           
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725

Query: 441  -AGALGQKGDLGLPGQPGLR---------GPSGIPGLQGPAGPIGPQGLPGLKGEPGLPG 490
              G  G KGD GLPG PG R         GP G PG++GPAG  G +G PGL G  GL G
Sbjct: 1726 QEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDG 1785

Query: 491  PPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
             PG  G +G  G AG  G PG  G PG+ G  G PGP GPPG PG   E G  GL+  NG
Sbjct: 1786 KPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG 1845

Query: 550  --GVEGAVLGKGGKPQFG 565
              G  G    KG K   G
Sbjct: 1846 EPGDPGEDGRKGEKGDSG 1863



 Score =  417 bits (1071), Expect = e-116
 Identities = 273/638 (42%), Positives = 318/638 (49%), Gaps = 120/638 (18%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGP 81
            GPR   G  G  G  G A  +  +P  +GP GPP                P+   G+PGP
Sbjct: 2144 GPRGQDGNPGLPGERGMAGPEG-KPGLQGPRGPPG---------------PVGGHGDPGP 2187

Query: 82   PGKPG---PRGPPGPPGFPGKPG---------MGKPGLHGQPGPAGPPGFSRMGKAGPPG 129
            PG PG   P GP GP G  G+PG          G  G  G PGP GP G   +G  G PG
Sbjct: 2188 PGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGL--VGPQGSPG 2245

Query: 130  LPGKVGPPGQPGL------------RGEPGIRGDQGLRGPPGPPGLPGPSGI---TIPGK 174
            LPG+VG  G+PG             RG PG+ G  GL GP GP G PGP+G     + G 
Sbjct: 2246 LPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGL 2305

Query: 175  PGAQGVPGPPG-----FQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPP 228
            PGA+G  G PG       GEPG +G+ G PG RG KG+ G  G+PG PG  GQ GAPGP 
Sbjct: 2306 PGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPK 2365

Query: 229  GLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGL 288
            G  G  G+G PG  G PG PG KG+ G PG+PG  G  G  G  GP G   +G PG +G 
Sbjct: 2366 GFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGE--MGQPGPSGE 2423

Query: 289  PGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGV--PGLLGDRGEPG--- 343
             G  GP G +G PG  GPPG   P   G PG  G KGD+G  GV  PG  G+RGEPG   
Sbjct: 2424 RGLAGPPGREGIPGPLGPPG--PPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRG 2481

Query: 344  EDGEPGEQGPQGLGGPPGLPG---------SAGLPGRRG-------PPGPKG------EA 381
            EDG PG++GP+GL GPPG  G         SAGL G +G       PPGP+G      E 
Sbjct: 2482 EDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGER 2541

Query: 382  GPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPG-- 439
            GP G  G  G RGD G  G  G  G PG++G  G  G  G  GP+G+PG  G PG PG  
Sbjct: 2542 GPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSP 2601

Query: 440  ----VAGALGQKGDLGLPGQPGLRGPSGIPGL---------QGPAGPIGPQGLPGLKGEP 486
                V G  G+KGD+G  G  GL+G  G+ G          +G AGP G  GL G KGE 
Sbjct: 2602 GKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEM 2661

Query: 487  GLPGPPGEGRA----------------GEPGTAGPTGPPGVPGSPGITGPPGPPG----- 525
            G PG PG+  A                G+PG  G  G  G  G+PGI G PGP G     
Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSA 2721

Query: 526  -PPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKP 562
             PPGPPG+ G     G+ G     G     V+G  G P
Sbjct: 2722 GPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVP 2759



 Score =  415 bits (1067), Expect = e-116
 Identities = 276/627 (44%), Positives = 305/627 (48%), Gaps = 141/627 (22%)

Query: 58   EGKGQYLEMPLPLL-PMDLKGEPGPPGKPGPRGPPGPPGFPGKPG----MGKPGLH-GQP 111
            E  G +L +P     P    GE GPPGK GP G PG  G  G  G     G PGL  G+ 
Sbjct: 1965 ESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGER 2024

Query: 112  GPAGPPGFS-RMGKAGPPGLPGKVGP------PGQPGLRGEPGIRGDQGLRGPPGPPGLP 164
            GP GP G +   GK G PGLPG+ G       PG+ G RGE G RG+QG  GPPG PG P
Sbjct: 2025 GPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTP 2084

Query: 165  GPSG-------ITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPG 217
            GP G       +  PG PG  G  GPPG +G    +GEPG  GD+G KGD GV     PG
Sbjct: 2085 GPPGPPGPKVSVDEPG-PGLSGEQGPPGLKGA---KGEPGSNGDQGPKGDRGV-----PG 2135

Query: 218  APGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGP---PGVPGPRGEPGAVGPKGP 274
              G  G PGP G            DG PG PG++G +GP   PG+ GPRG PG VG  G 
Sbjct: 2136 IKGDRGEPGPRGQ-----------DGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD 2184

Query: 275  PGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPG--LIGPTG-YGMPGLPGPKGDRGPAG 331
            PG  G   PG AG  GPQGPSG KGEPG  GPPG  L GPTG  G+PG PGP G  GP G
Sbjct: 2185 PGPPGA--PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG 2242

Query: 332  VPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPG--- 388
             PGL G  GE G+ G PG  G  G  G  G PG  G PG  GP GPKGE GP G PG   
Sbjct: 2243 SPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAV 2302

Query: 389  -------------------------------VPGIRGDQGPSGLAGKPGVPGERG----- 412
                                           +PG RG++G +G AG+PG PGE G     
Sbjct: 2303 VGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP 2362

Query: 413  ------------LPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG--- 457
                        +PG+ GPPGP G KG+ G  G PG PGV G  GQ G  G  GQPG   
Sbjct: 2363 GPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSG 2422

Query: 458  ---LRGP---SGIPGLQGPAGP---IGPQGLPGLKGEPGLPG---PPGEGRAGEPGTAGP 505
               L GP    GIPG  GP GP   +GP G  GLKG+ G PG   P   G  GEPG  G 
Sbjct: 2423 ERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGE 2482

Query: 506  TGPPGVPGSPGITGPPGPP-------------------------GPPGPPGAPGAFDETG 540
             G PG  G  G+TGPPG                           GPPGP GA G   E G
Sbjct: 2483 DGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG 2542

Query: 541  IAGLHLPNG--GVEGAVLGKGGKPQFG 565
              GL    G  G  G    KG K + G
Sbjct: 2543 PRGLDGDKGPRGDNGDPGDKGSKGEPG 2569



 Score =  409 bits (1050), Expect = e-114
 Identities = 271/625 (43%), Positives = 308/625 (49%), Gaps = 118/625 (18%)

Query: 24   PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK-GQYLEMPLPLLPMDLKGEPGPP 82
            P      G  G+ G  P     P ++GP GP    G  GQ +    P LP   KG+PGP 
Sbjct: 1316 PGTPGAPGLKGSPGL-PGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLP-GRKGDPGPS 1373

Query: 83   GKPGPRGP---PGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKA-GPPGLPG------ 132
            G PGPRGP   PGP G PG PG    G  G  G  GPPG    G A G PGLPG      
Sbjct: 1374 GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433

Query: 133  ---KVGPPGQ-----------PGLRGEPGIRGDQGLRGPPG------------------- 159
                VGPPG+           PGL G+PG  G+QG RGPPG                   
Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGE 1493

Query: 160  -----PPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGD--------RGLK 205
                 PPG  G  G+  + G+PGA+G  GPPG  G  G +GEPG PGD         G K
Sbjct: 1494 KGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPK 1553

Query: 206  GDNG-VGQPGLPGAPGQGGAPGPPGL-----PGPAG-LGKPGLDGLPGAPGDKGESGPPG 258
            G+ G VG  G  GA G  G  GPPGL     PGP G  G  G  GL G  G  G+SGPPG
Sbjct: 1554 GEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPG 1613

Query: 259  VPGPRGEPGAVGPKGPPGVDGV-------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIG 311
              G  G PG  GP GP G DG        G PG  GLPG  G  G +G PG RGP G  G
Sbjct: 1614 EKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKG 1673

Query: 312  PTG-------YGMPGLPGPKGDRGPAGVPGLLG----------DRGEPGEDGEPGEQGPQ 354
              G        G PG  GPKGDRG  G PG  G          ++GEPG+ G+ G +GP+
Sbjct: 1674 DQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPK 1733

Query: 355  GLGGPPGLPGSAGLPGRRGPPGPKG---------EAGPGGPPGV---------PGIRGDQ 396
            G  G PG PG  G+ G RGPPGP+G         E G  GPPG+         PG  G  
Sbjct: 1734 GDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS 1793

Query: 397  GPSGLAGKPGVPGERGLPGAHGP---PGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLP 453
            GP+G AGK G PG  GLPG  G    PGP+GP G PG  G  G PG+ G  G+ GD G  
Sbjct: 1794 GPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED 1853

Query: 454  GQPGLRGPSGIPGLQGPAGPIGPQGLPGL---KGEPGLP---GPPGEGRAGEPGTAGPTG 507
            G+ G +G SG  G +G  GP G +G PG+   +G PGLP   GPPG+G  G PG  GP G
Sbjct: 1854 GRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKG 1913

Query: 508  PPGVPGSPGITGPPGPPGPPGPPGA 532
              G  GS G  G PG  G  G PG+
Sbjct: 1914 DRGETGSKGEQGLPGERGLRGEPGS 1938



 Score =  407 bits (1046), Expect = e-113
 Identities = 281/658 (42%), Positives = 310/658 (47%), Gaps = 173/658 (26%)

Query: 48   QKGPVGPPFR---EGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG-MG 103
            + GP GPP R    G G              KGEPG  G+ GPRGP G PG PG PG  G
Sbjct: 1698 EPGPPGPPGRLVDTGPGARE-----------KGEPGDRGQEGPRGPKGDPGLPGAPGERG 1746

Query: 104  KPGLHGQPGPAGPPGF----SRMGKAGPPGL---------PGKVGPPG---------QPG 141
              G  G PGP G PG        G  GPPGL         PG  GP G          PG
Sbjct: 1747 IEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPG 1806

Query: 142  LRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGD 201
              G PG+RG+QGL GP GPPGLPG  G    GKPG  G  G PG  GE G +GE G  G 
Sbjct: 1807 RDGLPGLRGEQGLPGPSGPPGLPGKPGED--GKPGLNGKNGEPGDPGEDGRKGEKGDSGA 1864

Query: 202  RGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGP---- 256
             G +G +G  G+ G PG  G  G PG PG  GP G G PG+ G  G  GD+GE+G     
Sbjct: 1865 SGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQ 1924

Query: 257  --PGVPGPRGEPGAV---------------------------------------GPKG-- 273
              PG  G RGEPG+V                                       GPKG  
Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984

Query: 274  ----PPGVDG-VGVPGAAGL------PGPQGPSG-AKGEPGTRGPPGLIGPTGY-GMPGL 320
                PPG +G +G PG  GL      PGPQGP G A GE G  GP GL G  G  G+PGL
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044

Query: 321  PGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPK-- 378
            PG  G  G AG PG      E GE GE GE+G QG  GPPGLPG+ G PG   PPGPK  
Sbjct: 2045 PGRAGGVGEAGRPG------ERGERGEKGERGEQGRDGPPGLPGTPGPPG---PPGPKVS 2095

Query: 379  -GEAGPG-----GPPGV------PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPK 426
              E GPG     GPPG+      PG  GDQGP G  G PG+ G+RG PG  G  G  G  
Sbjct: 2096 VDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLP 2155

Query: 427  GEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEP 486
            GE G  G  G PG+ G  G  G +G  G PG   P G PGL GPAGP GP GL   KGEP
Sbjct: 2156 GERGMAGPEGKPGLQGPRGPPGPVGGHGDPG---PPGAPGLAGPAGPQGPSGL---KGEP 2209

Query: 487  GLPGPPG------------------------EGRAGEPGTAGPTGPPGVP---------- 512
            G  GPPG                        +G  G PG  G TG PG P          
Sbjct: 2210 GETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDG 2269

Query: 513  --GSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPN--------GGVEGAVLGKGG 560
              GSPG+ G PG PGP GP G PG     G A + LP         GG+ G ++G+ G
Sbjct: 2270 DRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPG 2327



 Score =  380 bits (975), Expect = e-105
 Identities = 244/541 (45%), Positives = 275/541 (50%), Gaps = 88/541 (16%)

Query: 110  QPGPAGPPGFSRMGKAGPPG---LPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPP----- 161
            QP P   P +   G+ G PG   L G+VGPPG PGL   PG  G  G +GPPG       
Sbjct: 1241 QPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGL---PGRTGAPGPQGPPGSATAKGE 1297

Query: 162  -GLPGPSGIT-IPGKPGAQGVPGPPGFQGE---PGPQGEPGPPGDRGLKGDNG-----VG 211
             G PG  G    PG+ G  G PG PG +G    PGP+G+PG  G RG KG+ G     +G
Sbjct: 1298 RGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIG 1357

Query: 212  QPGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAP--------GDKGESGP------ 256
              G PG PG+ G PGP G PGP G LG PG  G PG P        GD+GE GP      
Sbjct: 1358 GEG-PGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEG 1416

Query: 257  ------PGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLI 310
                  PG+PG  G PG  GP GPPG  G       G PG  G  G+ GE G RGPPG I
Sbjct: 1417 GIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAI 1476

Query: 311  GPTG-YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLP 369
            GP G  G PG  G  G++G  G PG  G RG PG  G PG +GP+G  GP G  G  G P
Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536

Query: 370  GR-----------RGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA-----GKPGVPGER-- 411
            GR            GP G KG+ GP GP G  G++G++GP GL      G  G PG+R  
Sbjct: 1537 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP 1596

Query: 412  -GLPGAHGPPGPTGPKGEPGFTGRPGGPGVA------GALGQKGDLGLPGQPGL------ 458
             GL G  GPPG +GP GE G  GRPG PG        G +G+KGD G PG PGL      
Sbjct: 1597 IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656

Query: 459  RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG-EGRAGEPGTAGPTG-----PPGV- 511
            RG  G PG++GP G  G QG PG  G  G PG  G +G  GEPG  GP G      PG  
Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR 1716

Query: 512  -PGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG-----GVEGAVLGKGGKPQFG 565
              G PG  G  GP GP G PG PGA  E GI G   P G     GV G    KG +   G
Sbjct: 1717 EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPG 1776

Query: 566  L 566
            L
Sbjct: 1777 L 1777



 Score =  327 bits (839), Expect = 2e-89
 Identities = 208/452 (46%), Positives = 234/452 (51%), Gaps = 73/452 (16%)

Query: 167  SGITIPGKPGAQGVPGPPGFQGEPGP---QGEPGPPGDRGLKGDNGVGQPGLPGAPGQGG 223
            +  T   +P    V  P G +GEPG    +G+ GPPGD GL G  G   PG  G PG   
Sbjct: 1236 ASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGA--PGPQGPPGSAT 1293

Query: 224  APGPPGLPGPAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGV----- 277
            A G  G PG  G  G PG  G PG PG  G  G PG+PGPRG+PG  GP+GP G      
Sbjct: 1294 AKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPG 1353

Query: 278  -----DGVGVPGAAGLPGPQGPSGAK---GEPGTRGPPGLIGPTGYGMPGLPGPKGDRGP 329
                 +G G+PG  G PGP GP G +   G+PG RGPPGL    G  M G  G +G+RGP
Sbjct: 1354 QVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGL---PGTAMKGDKGDRGERGP 1410

Query: 330  AGVPGLLG-DRGEPGEDGEPGEQGPQGLGGP--------------PGLPGSAGLPGRRGP 374
             G PG  G   GEPG  G PG  GPQG  GP              PGLPG  G PG +GP
Sbjct: 1411 PG-PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGP 1469

Query: 375  PGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA---------HGPPGPTGP 425
             GP G  GP G  G PG  G+ G  G  G PG  G RGLPG           GPPGPTG 
Sbjct: 1470 RGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGR 1529

Query: 426  KGEPGFTGRPG-----GPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 480
            +GE G  GRPG     GP VAG  G+KGD+   G  G RG +G+ G +GP G + P G P
Sbjct: 1530 QGEKGEPGRPGDPAVVGPAVAGPKGEKGDV---GPAGPRGATGVQGERGPPGLVLP-GDP 1585

Query: 481  GLKGEPGLPGPPG-EGRAGEPGTAGPTGPPGVPGSPGITGPPGP------------PGPP 527
            G KG+PG  GP G  GRAG PG +GP G  G PG PG  GP GP             GPP
Sbjct: 1586 GPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP 1645

Query: 528  GPPGAPGAFDETGIAGLHLPNGGVEGAVLGKG 559
            G PG PG   E G+ G      GV G V  KG
Sbjct: 1646 GDPGLPGKAGERGLRGA----PGVRGPVGEKG 1673



 Score =  187 bits (476), Expect = 2e-47
 Identities = 124/295 (42%), Positives = 141/295 (47%), Gaps = 47/295 (15%)

Query: 343  GEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA 402
            G+ GEPGE G +G  GPPG PG   LPGR G PGP+G      PPG    +G++G  G  
Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPG---LPGRTGAPGPQG------PPGSATAKGERGFPGAD 1304

Query: 403  GKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ------P 456
            G+PG PG  G PG    PG  G KG PG  G  G PG  G  G KG+ G PGQ      P
Sbjct: 1305 GRPGSPGRAGNPGT---PGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGP 1361

Query: 457  GLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGP------PG 510
            GL G  G PG  GP GP GP G PG +G PGLPG   +G  G+ G  GP GP      PG
Sbjct: 1362 GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPG 1421

Query: 511  VPGSPGITGPPGPPGPPGPP-----------GAPGAFDETGIAGLHLPNGGVEGAVLGKG 559
             PG PG+ G PGP GP GPP           GAPG   + G  G   P  G  GA+  KG
Sbjct: 1422 EPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPR-GPPGAIGPKG 1480

Query: 560  GK----PQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATG 610
             +    P    GE      P        P  + G+P    R    G  G    TG
Sbjct: 1481 DRGFPGPLGEAGEKGERGPP-------GPAGSRGLPGVAGRPGAKGPEGPPGPTG 1528


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  423 bits (1087), Expect = e-118
 Identities = 252/551 (45%), Positives = 285/551 (51%), Gaps = 67/551 (12%)

Query: 46   PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GK 104
            P   G +GPP  +G    +  P  +      G PGPPG PG  G  G PG PG  G  G 
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAI------GPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 105  PGLHGQPGPAGPPGFSRM----GKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160
            PG  G+ G  G PG S +    G  G PGL G  G PG+ G RG PG+ G +GL+G PGP
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 161  PGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG----VGQPGLP 216
             G PGP G       G+ G PG PG +G PG  G  G PG +G +G  G     G+PGLP
Sbjct: 990  AGPPGPRGDL-----GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLP 1044

Query: 217  GAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPG 276
            G  G  G  G PG       G PG  G PG PGD G+ G  G PGP G  G  GP+G PG
Sbjct: 1045 GIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 277  VDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGP---KGDRGPAGV 332
                G PG  G PGP G  G KG  G  GPPG+ GP G  G PG PGP   +GD+G  G+
Sbjct: 1105 --SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI 1162

Query: 333  PGLLGDRGE-------PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385
            PG  G++GE       PG  G PG QG +G  G PG PG  G  G  G  GP+G  G  G
Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222

Query: 386  PPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGP-----KGEPGFTGRPGG--- 437
             PG PG+ G   P G  G  G PG RG PGA GPPGP G      KG+ G  G PG    
Sbjct: 1223 FPGPPGLPGAIIP-GQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 438  PGVAGALGQKGDLGLPGQPGLRGPSGIPGLQG------------------PAGPIGPQGL 479
            PG AG +G  G LG PG PGL GP G PG QG                  P GPIGP+G 
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 480  PGLKGEPG------LPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA 532
            PG++G+PG      LPG PG  G  GEPG  G  GPPG PG+ G  GP G PG  G PG 
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGT 1401

Query: 533  PGAFDETGIAG 543
            PG   E G  G
Sbjct: 1402 PGPAGEKGNKG 1412



 Score =  417 bits (1073), Expect = e-116
 Identities = 270/613 (44%), Positives = 310/613 (50%), Gaps = 89/613 (14%)

Query: 24   PRASSGGGAGGAAGYAPVKY--IQPMQ--KGPVGPPFREGKGQYLEMPLPLLPMDLKGEP 79
            P +    G  G  GY P     +Q  Q   G  GPP   G    L +  P+        P
Sbjct: 604  PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV--------P 655

Query: 80   GPPGKPGPRGPPGPPGFPGKPG-MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPG 138
            GPPG PGP G PGP G PG PG +GK G  G PGP G PG   +G  GPPG  G  G PG
Sbjct: 656  GPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPG 715

Query: 139  QPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGP 198
              G  G PG  G+ GL G PG PG  G   + +PG PG  G PG  G  GE G  G PG 
Sbjct: 716  TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 199  PGDRGLKGDNGV----GQPGLPGAPGQGGAPG--------PPGLPGPAGL-------GKP 239
            PG  G  G+ G+    G PG PG PG+ G PG          GLPG  GL       GK 
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKT 835

Query: 240  GLDGLPGAPG-DK----GESGPPGVPGPRGEPGAVGPKG---------PPGVDGV-GVPG 284
            G  G PG PG D+    GE+G PG+PG +GE G +G +G         PPG DGV G+ G
Sbjct: 836  GPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG 895

Query: 285  AAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGPKGDRG---PAGVPGLLGDRG 340
              G  GP GP G  G PG RG PG+ G  G  G PG  G +GD+G   P+ +  ++GD+G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 341  EPGEDG---EPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
            EPG  G    PGE+G +G+ G PGL G  GLPG  GPPGP+G+ G  G PG PG+RG  G
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 398  PSGLAGKPG---------VPGERGLPGAHGPPGPTGPKGEPGFTG--RPGGPGVAGALGQ 446
              G  G PG          PG  G PG  G  G  G KGEPG++   RPG PG  G    
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG---- 1071

Query: 447  KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG----------EGR 496
              D GLPG  G +G  G PG  G  GP GP+G PG  G PGLPG PG          +G 
Sbjct: 1072 --DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129

Query: 497  AGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLP-----NGGV 551
             G PG  GP G PG PGSPG  G  G  G  G PG  G   ETG+  L  P     N G 
Sbjct: 1130 LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL--LRAPPGPRGNPGA 1187

Query: 552  EGAVLGKGGKPQF 564
            +GA  G  G P F
Sbjct: 1188 QGA-KGDRGAPGF 1199



 Score =  411 bits (1056), Expect = e-114
 Identities = 273/643 (42%), Positives = 316/643 (49%), Gaps = 93/643 (14%)

Query: 45   QPMQKGPVGPPFREG-KGQYLEMPLPLLPMDLKGE---------PGPPGKPGPRGPPGPP 94
            QP +KG  G P   G KG    +P P   + L GE         PG PG PGP GP GPP
Sbjct: 561  QPGRKGLDGIPGTPGVKG----LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616

Query: 95   GF--PGKPGM----GKPGLHGQPGPAGPPGFSRM-----GKAGPPGLPGKVGPPGQPGLR 143
            G+   G+PG+    G PG  G PG AGP G   +     G  GPPG PG  GP G PG+ 
Sbjct: 617  GYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676

Query: 144  GEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRG 203
            G  G  GD GL GP G PG+PG      PG  G QG PG  G  G PG  GEPG PG  G
Sbjct: 677  GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPG 736

Query: 204  LKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGP 262
            L G  G     +PG PG  G PG  G  G  G +G PGL GLPG PG++G      + GP
Sbjct: 737  LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG------LDGP 790

Query: 263  RGEPGAVGP---KGPPGVDGVGVPGAAGLP---GPQGPSGAKGEPGTRGPPGLIG----- 311
            RG+PG  GP   +GPPG    G  GA GLP   G +G  G +G+ G +G PG+ G     
Sbjct: 791  RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 312  -PTGYGMPGLPGPKGDRGP---AGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG 367
             P   G PG+PG +G+ GP    G PG  G  G PGEDG  G  G  G  GPPG PG+ G
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910

Query: 368  LP------------GRRGPPGPKGEAG----PG-----------GPPGVPGIRGDQGPSG 400
             P            G+RG PG KGE G    PG           G PG+ G  G+ G  G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 401  LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
              G PG+PG +GL G  GP GP GP+G+ G TG PG PG+ G  G  G++G+PG  G RG
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 461  PSGIPGLQGPAGPIGPQGLPGLKGEPGL-----PGPPG-EGRAGEPGTAGPTGPPGVPGS 514
              G PG  G  G  G  GL G KGEPG      PGPPG  G  G PG  G  G  G PG 
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 515  PGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHAT 574
            PG  GP GP G PG PG+PG   + G  G  L   G++G            LG       
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHG-DLGFKGIKGL-----------LGPPGIRGP 1138

Query: 575  PAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVG 617
            P       SP P  G+     R    G +G    TG+   P G
Sbjct: 1139 PGLPGFPGSPGP-MGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180



 Score =  392 bits (1007), Expect = e-109
 Identities = 280/711 (39%), Positives = 320/711 (45%), Gaps = 176/711 (24%)

Query: 11  LLLLLLVLVLGCGPRASSG-----------GGAGGAAGYAPVKYIQPMQKGPVGPPFREG 59
           LLL LL+++L   P AS G            GA G  G          +KG  GPP   G
Sbjct: 12  LLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKG----------EKGFPGPPGSPG 61

Query: 60  KGQYLE---MPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAG 115
           +  +     +P P  P    G PG  G  G RG  G PGF G PG+ G PG  G  G  G
Sbjct: 62  QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG 121

Query: 116 PPGFS-RMGKAGPPGLPGKVGPPGQPGLRGEPGIRG--------DQGLRGPPGPPGLPGP 166
            PG S   G+ G PGLPG +G PG PG  G  G +G        +   +G PG PG PGP
Sbjct: 122 VPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGP 181

Query: 167 SGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG---VGQPGLPGAPGQGG 223
            G+     PG  G PGP G  G PG  G PG  G RG KG  G   +G  G  G  G  G
Sbjct: 182 QGL-----PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTG 236

Query: 224 APGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGP-----------RGEPGAVGPK 272
            PGPPG       G      L G  GDKG  G PG PGP           +G PG  G +
Sbjct: 237 PPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQ 296

Query: 273 GPPGVDGV-------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY---------- 315
           G PG DGV       GV G  G PG  G  G KG+ G  GPPG  GPT Y          
Sbjct: 297 GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356

Query: 316 GMPGLPGPKGDRGP--------------------AGVPGLLGDRGEPGEDGEPGEQ---- 351
           G PG PGP+G RGP                     G PG  G +G  GE G PG+     
Sbjct: 357 GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416

Query: 352 -GPQGLGGPPGLPGSAGLPG-------RRGPPGPKGEAGPGGPPGVPGIRGDQ------- 396
            G  G  G PGLPGS G PG       R+GPPG  G  G  G PG+PG+ G +       
Sbjct: 417 PGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLC 476

Query: 397 -------GPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQ--- 446
                  GP GL G PG+ G +G+PG  G  G  G  G PG TG PG PG  GA G    
Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536

Query: 447 ----------KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG------LKGEPGLPG 490
                     +G +G+PG PGLRG  G  GL G  G  G +GLPG      L GE G  G
Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596

Query: 491 PPGE-GRAGEPGTAGPTGPP--------------GVPGSPG----------------ITG 519
           PPG+ G  G PG AGP GPP              GVPG+PG                + G
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 520 PPGPPGPP------GPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKP 562
           PPGPPGPP      GPPG PG+  + G  GL  P+G  G+ G  +G  G P
Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG--IGFPGPP 705



 Score =  330 bits (847), Expect = 2e-90
 Identities = 211/495 (42%), Positives = 244/495 (49%), Gaps = 72/495 (14%)

Query: 24   PRASSGGGAGGAAGYAPVKYI-----QPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGE 78
            P A    G  G  G + + ++     +P  KG  G P  +G      MP       LKG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGL---KGLKGL 986

Query: 79   PGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPG 138
            PGP G PGPRG  G  G PG+PG+   G+ G  G  G PG    GK G  G PG+ G PG
Sbjct: 987  PGPAGPPGPRGDLGSTGNPGEPGLR--GIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPG 1042

Query: 139  QPGLRGEPGIRGDQGLR-----GPPGP---PGLPGPSG----ITIPGKPGAQGVPGP--- 183
             PG+ G  G +G+ G       GPPGP   PGLPG  G    +  PG PG  G  GP   
Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGA 1102

Query: 184  PGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPG------------L 230
            PG  G PG  G+PGP GD G KG  G+ G PG+ G PG  G PG PG            +
Sbjct: 1103 PGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI 1162

Query: 231  PGPAG--------LGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV-G 281
            PGPAG           PG  G PGA G KG+ G PG PG  G  GA+G  GP G  G+ G
Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222

Query: 282  VPGAAGLPGP--------QGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVP 333
             PG  GLPG         +GP G++G PG  GPPG  G    G+ G  G  G  GP G P
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPP 1282

Query: 334  GLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPP------GPKGEAGPGGPP 387
            G  GD G PG  G PG  G  G  G PG  G  G+ G +G P      GP G  GP GPP
Sbjct: 1283 GTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342

Query: 388  GVPG---------IRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGP 438
            GV G         + G  GP G  G+PG+ GE G PG  G  GP GP+G+PG  G+PG P
Sbjct: 1343 GVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTP 1402

Query: 439  GVAGALGQKGDLGLP 453
            G AG  G KG  G P
Sbjct: 1403 GPAGEKGNKGSKGEP 1417



 Score =  260 bits (664), Expect = 3e-69
 Identities = 178/435 (40%), Positives = 202/435 (46%), Gaps = 106/435 (24%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMP----LPLLP--MDL 75
            GPR   G  G  G  G   +    P   G +G P  +GK   L  P     P LP    L
Sbjct: 994  GPRGDLGSTGNPGEPGLRGI----PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 76   KGEPGPPG-----KPGPRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPGFSRMGKAG 126
            +G+ G PG     +PGP GP G PG PG  G    MG+PG  G  GPAGP G    G  G
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAP--GSPG 1107

Query: 127  PPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG-PSGITIPGKPGAQGVPGPPG 185
             PGLPGK GP G  G +G  G+ G  G+RGPPG PG PG P  + I G  G  G+PGP G
Sbjct: 1108 SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167

Query: 186  FQGEPG----PQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGA---------------PG 226
             +GE G    P G  G PG +G KGD G   PG PG PG+ GA               PG
Sbjct: 1168 EKGETGLLRAPPGPRGNPGAQGAKGDRGA--PGFPGLPGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 227  PPGLPG------------PAGLGKPGLDGLPGAPGD-----KGESGPPGVPGPRGEPGAV 269
            PPGLPG            P   G PG  G PG PG      KG+ G  G PGP+G PG  
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTA 1285

Query: 270  GPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRG------------PPGLIGPTGY-- 315
            G  GPPG   +G PG  GLPGP+G  G +G PG +G            PPG IGP G   
Sbjct: 1286 GDMGPPG--RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343

Query: 316  --------------------------GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPG 349
                                      GM G PGP    GP G  G  G RG+PG+DG+PG
Sbjct: 1344 VRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP---GPPGNLGPCGPRGKPGKDGKPG 1400

Query: 350  EQGPQGLGGPPGLPG 364
              GP G  G  G  G
Sbjct: 1401 TPGPAGEKGNKGSKG 1415



 Score =  255 bits (652), Expect = 9e-68
 Identities = 176/440 (40%), Positives = 202/440 (45%), Gaps = 103/440 (23%)

Query: 220 GQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG 279
           G  G  G  G PGP           PG+PG KG +GP G+PGP+G      PKG PG+ G
Sbjct: 43  GAKGEKGEKGFPGP-----------PGSPGQKGFTGPEGLPGPQG------PKGFPGLPG 85

Query: 280 V----GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-------YGMPGLPGPKGDRG 328
           +    GV G +GLPG  G  G  G PG  GP GL+G  G        G PGLPG  G  G
Sbjct: 86  LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 329 PAGVPGLLGDRGEP-----------GEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP 377
             G  GL G +G P           G+ G PG  GPQGL GPPG PG  G PG  G  G 
Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 378 KGEAGPGGPPG-----VPGIRGDQGPSGLAGKPGVPG-----------------ERGLPG 415
            G  GP GP G     V G +G++G  GL G PG PG                 E+G  G
Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 416 AHGPPGPTGPKGEPGFT-----GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGL--- 467
           A G PGP GP G PG +     G PG PG+ G  G+ G  G PG  G++G  G PGL   
Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 468 ---QGPAGPIGPQGLPGL---------KGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSP 515
              +G  G IGP G  G          KG+ G PGPPG    G  G  GP+GPPGVPGSP
Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGP--RGARGPQGPSGPPGVPGSP 383

Query: 516 G-----ITGPPGPPG--------------PPGPPGAPGAFDETGIAGLHLPNGGVEGAVL 556
           G     + G PG PG                G PG+PG     G+ G   P G     V 
Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443

Query: 557 GKGGKPQFGL-GELSAHATP 575
            KG     GL G L +   P
Sbjct: 444 RKGPPGDHGLPGYLGSPGIP 463



 Score =  178 bits (452), Expect = 1e-44
 Identities = 115/281 (40%), Positives = 134/281 (47%), Gaps = 62/281 (22%)

Query: 338 DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
           D+G+   DG  GE+G +G  GPPG PG  G  G  G PGP+G   P G PG+PG+ G +G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQG---PKGFPGLPGLTGSKG 91

Query: 398 PSGLAGKPGVPGERGLPGAHGPPGP---------TGPKGEPGFTGRPGG---PGVAGALG 445
             G++G PG  G  GLPG  G  GP         +G KGE GF G PG    PG+ GA G
Sbjct: 92  VRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151

Query: 446 QKGDLGL--------------PGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGP 491
            KG  G               PG PG  GP G+PG  G  GP+GP G PG  G PG  GP
Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGP 211

Query: 492 PGE---------GRAGEPGTAGPTGPPGVPGSPGIT-----------------GPPGPPG 525
            G          G  GE G  G TGPPG PG+  +T                 G  G PG
Sbjct: 212 RGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPG 271

Query: 526 PPGPPGAPGAF--DETGIAGLHLPNGGVEGAVLGKGGKPQF 564
           PPGP G PG     E G  G    + G++G   GK G P F
Sbjct: 272 PPGPSGLPGESYGSEKGAPG----DPGLQGKP-GKDGVPGF 307



 Score =  154 bits (390), Expect = 2e-37
 Identities = 94/227 (41%), Positives = 114/227 (50%), Gaps = 11/227 (4%)

Query: 373 GPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFT 432
           G  G KGE G  GPPG PG +G  GP GL G  G  G  GLPG  G  G  G  G PGF+
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 433 GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP 492
           G PG PG  G  G  G +G+PG  G +G  G PGL G  G  G  G  GLKG+ G P   
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 493 GE---GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
            +      G+PG  G  GP G+PG PG    PGP GPPGP   PG F   G  G   P G
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGF---PGPVGPPGP---PGFFGFPGAMGPRGPKG 216

Query: 550 GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDR 596
            +   V+G  G  + G+  L+    P  T ++T   P +   +K ++
Sbjct: 217 HMGERVIGHKG--ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEK 261


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  423 bits (1087), Expect = e-118
 Identities = 252/551 (45%), Positives = 285/551 (51%), Gaps = 67/551 (12%)

Query: 46   PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GK 104
            P   G +GPP  +G    +  P  +      G PGPPG PG  G  G PG PG  G  G 
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAI------GPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 105  PGLHGQPGPAGPPGFSRM----GKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160
            PG  G+ G  G PG S +    G  G PGL G  G PG+ G RG PG+ G +GL+G PGP
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 161  PGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG----VGQPGLP 216
             G PGP G       G+ G PG PG +G PG  G  G PG +G +G  G     G+PGLP
Sbjct: 990  AGPPGPRGDL-----GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLP 1044

Query: 217  GAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPG 276
            G  G  G  G PG       G PG  G PG PGD G+ G  G PGP G  G  GP+G PG
Sbjct: 1045 GIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 277  VDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGP---KGDRGPAGV 332
                G PG  G PGP G  G KG  G  GPPG+ GP G  G PG PGP   +GD+G  G+
Sbjct: 1105 --SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI 1162

Query: 333  PGLLGDRGE-------PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385
            PG  G++GE       PG  G PG QG +G  G PG PG  G  G  G  GP+G  G  G
Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222

Query: 386  PPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGP-----KGEPGFTGRPGG--- 437
             PG PG+ G   P G  G  G PG RG PGA GPPGP G      KG+ G  G PG    
Sbjct: 1223 FPGPPGLPGAIIP-GQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 438  PGVAGALGQKGDLGLPGQPGLRGPSGIPGLQG------------------PAGPIGPQGL 479
            PG AG +G  G LG PG PGL GP G PG QG                  P GPIGP+G 
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 480  PGLKGEPG------LPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA 532
            PG++G+PG      LPG PG  G  GEPG  G  GPPG PG+ G  GP G PG  G PG 
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGT 1401

Query: 533  PGAFDETGIAG 543
            PG   E G  G
Sbjct: 1402 PGPAGEKGNKG 1412



 Score =  411 bits (1056), Expect = e-114
 Identities = 273/643 (42%), Positives = 316/643 (49%), Gaps = 93/643 (14%)

Query: 45   QPMQKGPVGPPFREG-KGQYLEMPLPLLPMDLKGE---------PGPPGKPGPRGPPGPP 94
            QP +KG  G P   G KG    +P P   + L GE         PG PG PGP GP GPP
Sbjct: 561  QPGRKGLDGIPGTPGVKG----LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616

Query: 95   GF--PGKPGM----GKPGLHGQPGPAGPPGFSRM-----GKAGPPGLPGKVGPPGQPGLR 143
            G+   G+PG+    G PG  G PG AGP G   +     G  GPPG PG  GP G PG+ 
Sbjct: 617  GYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676

Query: 144  GEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRG 203
            G  G  GD GL GP G PG+PG      PG  G QG PG  G  G PG  GEPG PG  G
Sbjct: 677  GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPG 736

Query: 204  LKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGP 262
            L G  G     +PG PG  G PG  G  G  G +G PGL GLPG PG++G      + GP
Sbjct: 737  LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG------LDGP 790

Query: 263  RGEPGAVGP---KGPPGVDGVGVPGAAGLP---GPQGPSGAKGEPGTRGPPGLIG----- 311
            RG+PG  GP   +GPPG    G  GA GLP   G +G  G +G+ G +G PG+ G     
Sbjct: 791  RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 312  -PTGYGMPGLPGPKGDRGP---AGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG 367
             P   G PG+PG +G+ GP    G PG  G  G PGEDG  G  G  G  GPPG PG+ G
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910

Query: 368  LP------------GRRGPPGPKGEAG----PG-----------GPPGVPGIRGDQGPSG 400
             P            G+RG PG KGE G    PG           G PG+ G  G+ G  G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 401  LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
              G PG+PG +GL G  GP GP GP+G+ G TG PG PG+ G  G  G++G+PG  G RG
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 461  PSGIPGLQGPAGPIGPQGLPGLKGEPGL-----PGPPG-EGRAGEPGTAGPTGPPGVPGS 514
              G PG  G  G  G  GL G KGEPG      PGPPG  G  G PG  G  G  G PG 
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 515  PGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHAT 574
            PG  GP GP G PG PG+PG   + G  G  L   G++G            LG       
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHG-DLGFKGIKGL-----------LGPPGIRGP 1138

Query: 575  PAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVG 617
            P       SP P  G+     R    G +G    TG+   P G
Sbjct: 1139 PGLPGFPGSPGP-MGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180



 Score =  402 bits (1033), Expect = e-112
 Identities = 288/732 (39%), Positives = 332/732 (45%), Gaps = 200/732 (27%)

Query: 24   PRASSGGGAGGAAGYAPVKY--IQPMQ--KGPVGPPFREGKGQYLEMPLPLLPMDLKGEP 79
            P +    G  G  GY P     +Q  Q   G  GPP   G    L +  P+        P
Sbjct: 604  PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV--------P 655

Query: 80   GPPGKPGPRGPPGPPGFPGKPG-MGKPGLHGQPGPAGPPGFSRMGKAGPPG--------- 129
            GPPG PGP G PGP G PG PG +GK G  G PGP G PG   +G  GPPG         
Sbjct: 656  GPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPG 715

Query: 130  ------LPGKVGPPGQPGLRGEPGIRGDQGLRGP--PGPPGLPGPSGIT----------- 170
                   PGK+G PG PG  G PG +G+  +  P  PG PG PG  G +           
Sbjct: 716  TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 171  --IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGA--- 224
              +PG PG +G+ GP G  G+PGP GE GPPG R ++G  G  G PGL G  GQ G    
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 225  ---PGPPGLPGPAGLGKPGLDGLPGAPGDKGESGP---------PGVPGPRGE------- 265
                G PG+PG    G PG  G PG PG +GE GP         PG+ GP GE       
Sbjct: 835  TGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMM 894

Query: 266  --PGAVGPKGPPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRGPPG------LIGPT 313
              PGA+GP GPPG  G     G PG  G+ G +G  GAKGE G +G PG      +IG  
Sbjct: 895  GFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDK 954

Query: 314  GY----GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLP 369
            G     G  G PG KG+RG  G+PGL G +G PG  G PG +G  G  G PG PG  G+P
Sbjct: 955  GEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP 1014

Query: 370  G---RRGPPGPKGEAG----PG--GPPGVPGIRGDQG--------------PSGLAGKPG 406
            G     G PG KG+ G    PG  G PG+PGI G QG              P G  G PG
Sbjct: 1015 GSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG 1074

Query: 407  VPGERGL---------PGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG 457
            +PG+ G          PG  GP GP G  G PG  G PG PG  G LG KG  GL G PG
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 458  LRGPSGIPGLQGPAGPIG----------------------------PQGLPGL------K 483
            +RGP G+PG  G  GP+G                            P+G PG       +
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194

Query: 484  GEPGLPGPPG-EGRAGEPGTAGPTG------PPGVPG-----------------SPGITG 519
            G PG PG PG +G  G+ G  GPTG      PPG+PG                 SPG  G
Sbjct: 1195 GAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254

Query: 520  PPGP-----------------PGPPGPPGA------PGAFDETGIAGLHLPNG--GVEG- 553
            PPGP                 PGP GPPG       PG     G  GL  P G  G +G 
Sbjct: 1255 PPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF 1314

Query: 554  -AVLGKGGKPQF 564
              V G+ G P F
Sbjct: 1315 PGVKGEKGNPGF 1326



 Score =  392 bits (1007), Expect = e-109
 Identities = 280/711 (39%), Positives = 320/711 (45%), Gaps = 176/711 (24%)

Query: 11  LLLLLLVLVLGCGPRASSG-----------GGAGGAAGYAPVKYIQPMQKGPVGPPFREG 59
           LLL LL+++L   P AS G            GA G  G          +KG  GPP   G
Sbjct: 12  LLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKG----------EKGFPGPPGSPG 61

Query: 60  KGQYLE---MPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAG 115
           +  +     +P P  P    G PG  G  G RG  G PGF G PG+ G PG  G  G  G
Sbjct: 62  QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG 121

Query: 116 PPGFS-RMGKAGPPGLPGKVGPPGQPGLRGEPGIRG--------DQGLRGPPGPPGLPGP 166
            PG S   G+ G PGLPG +G PG PG  G  G +G        +   +G PG PG PGP
Sbjct: 122 VPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGP 181

Query: 167 SGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG---VGQPGLPGAPGQGG 223
            G+     PG  G PGP G  G PG  G PG  G RG KG  G   +G  G  G  G  G
Sbjct: 182 QGL-----PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTG 236

Query: 224 APGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGP-----------RGEPGAVGPK 272
            PGPPG       G      L G  GDKG  G PG PGP           +G PG  G +
Sbjct: 237 PPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQ 296

Query: 273 GPPGVDGV-------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY---------- 315
           G PG DGV       GV G  G PG  G  G KG+ G  GPPG  GPT Y          
Sbjct: 297 GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356

Query: 316 GMPGLPGPKGDRGP--------------------AGVPGLLGDRGEPGEDGEPGEQ---- 351
           G PG PGP+G RGP                     G PG  G +G  GE G PG+     
Sbjct: 357 GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416

Query: 352 -GPQGLGGPPGLPGSAGLPG-------RRGPPGPKGEAGPGGPPGVPGIRGDQ------- 396
            G  G  G PGLPGS G PG       R+GPPG  G  G  G PG+PG+ G +       
Sbjct: 417 PGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLC 476

Query: 397 -------GPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQ--- 446
                  GP GL G PG+ G +G+PG  G  G  G  G PG TG PG PG  GA G    
Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536

Query: 447 ----------KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG------LKGEPGLPG 490
                     +G +G+PG PGLRG  G  GL G  G  G +GLPG      L GE G  G
Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596

Query: 491 PPGE-GRAGEPGTAGPTGPP--------------GVPGSPG----------------ITG 519
           PPG+ G  G PG AGP GPP              GVPG+PG                + G
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 520 PPGPPGPP------GPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKP 562
           PPGPPGPP      GPPG PG+  + G  GL  P+G  G+ G  +G  G P
Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG--IGFPGPP 705



 Score =  355 bits (912), Expect = 6e-98
 Identities = 229/519 (44%), Positives = 261/519 (50%), Gaps = 60/519 (11%)

Query: 24   PRASSGGGAGGAAGYAPVKYI-----QPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGE 78
            P A    G  G  G + + ++     +P  KG  G P  +G      MP       LKG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGL---KGLKGL 986

Query: 79   PGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPG 138
            PGP G PGPRG  G  G PG+PG+   G+ G  G  G PG    GK G  G PG+ G PG
Sbjct: 987  PGPAGPPGPRGDLGSTGNPGEPGLR--GIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPG 1042

Query: 139  QPGLRGEPGIRGDQGLR-----GPPGP---PGLPGPSG----ITIPGKPGAQGVPGP--- 183
             PG+ G  G +G+ G       GPPGP   PGLPG  G    +  PG PG  G  GP   
Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGA 1102

Query: 184  PGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAGL-GKPGL 241
            PG  G PG  G+PGP GD G KG  G+ G PG+ G PG    PG PG PGP G+ G  G 
Sbjct: 1103 PGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG---LPGFPGSPGPMGIRGDQGR 1159

Query: 242  DGLPGAPGDKGESGP-PGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKG 299
            DG+PG  G+KGE+G     PGPRG PGA G KG  G  G  G+PG  G  G  GP G  G
Sbjct: 1160 DGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG 1219

Query: 300  EPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPG--------LLGDRGEPGEDGEPGEQ 351
              G  GPPGL G    G  G  GP G RG  G PG        ++G +G+ G  G PG +
Sbjct: 1220 IEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPK 1279

Query: 352  GPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGV------PGIRGDQGPSGLAGKP 405
            GP G  G  G PG  G PG  G PGP+G+ G  G PGV      PG  G  GP G  G  
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339

Query: 406  GVPGERGLPGA------HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ---- 455
            G PG RG PG        G PGP G  GEPG  G PG PG  G LG  G  G PG+    
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 456  --PGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP 492
              PG  G  G  G +G  GP G  GLPGLKG+ G  G P
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score =  346 bits (888), Expect = 4e-95
 Identities = 217/470 (46%), Positives = 247/470 (52%), Gaps = 52/470 (11%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMP----LPLLP--MDL 75
            GPR   G  G  G  G   +    P   G +G P  +GK   L  P     P LP    L
Sbjct: 994  GPRGDLGSTGNPGEPGLRGI----PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 76   KGEPGPPG-----KPGPRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPGFSRMGKAG 126
            +G+ G PG     +PGP GP G PG PG  G    MG+PG  G  GPAGP G    G  G
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAP--GSPG 1107

Query: 127  PPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG-PSGITIPGKPGAQGVPGPPG 185
             PGLPGK GP G  G +G  G+ G  G+RGPPG PG PG P  + I G  G  G+PGP G
Sbjct: 1108 SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167

Query: 186  FQGEPG----PQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGL-GKPG 240
             +GE G    P G  G PG +G KGD G   PG PG PG+ GA G  G  GP G+ G PG
Sbjct: 1168 EKGETGLLRAPPGPRGNPGAQGAKGDRGA--PGFPGLPGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 241  LDGLPGA--PGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAK 298
              GLPGA  PG  G  GPPG    RG PGA GP GPPG   +G+ G  G  G  GP G  
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPG---SRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPP 1282

Query: 299  GEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGG 358
            G  G  GPPG +G  G   PGLPGP+GD G  G PG+ G++G PG  G  G  GP G  G
Sbjct: 1283 GTAGDMGPPGRLGAPG--TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKG 1340

Query: 359  PPGL---PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPG 415
            PPG+   PG+  +    G PGP       G PG PG++G+ GP G  G  G  G RG PG
Sbjct: 1341 PPGVRGDPGTLKIISLPGSPGPP------GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 416  AHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIP 465
              G PG  GP GE G  G  G PG AG+       GLPG  G RG SG P
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGS------DGLPGLKGKRGDSGSP 1438



 Score =  255 bits (652), Expect = 9e-68
 Identities = 176/440 (40%), Positives = 202/440 (45%), Gaps = 103/440 (23%)

Query: 220 GQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG 279
           G  G  G  G PGP           PG+PG KG +GP G+PGP+G      PKG PG+ G
Sbjct: 43  GAKGEKGEKGFPGP-----------PGSPGQKGFTGPEGLPGPQG------PKGFPGLPG 85

Query: 280 V----GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-------YGMPGLPGPKGDRG 328
           +    GV G +GLPG  G  G  G PG  GP GL+G  G        G PGLPG  G  G
Sbjct: 86  LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 329 PAGVPGLLGDRGEP-----------GEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP 377
             G  GL G +G P           G+ G PG  GPQGL GPPG PG  G PG  G  G 
Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 378 KGEAGPGGPPG-----VPGIRGDQGPSGLAGKPGVPG-----------------ERGLPG 415
            G  GP GP G     V G +G++G  GL G PG PG                 E+G  G
Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 416 AHGPPGPTGPKGEPGFT-----GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGL--- 467
           A G PGP GP G PG +     G PG PG+ G  G+ G  G PG  G++G  G PGL   
Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 468 ---QGPAGPIGPQGLPGL---------KGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSP 515
              +G  G IGP G  G          KG+ G PGPPG    G  G  GP+GPPGVPGSP
Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGP--RGARGPQGPSGPPGVPGSP 383

Query: 516 G-----ITGPPGPPG--------------PPGPPGAPGAFDETGIAGLHLPNGGVEGAVL 556
           G     + G PG PG                G PG+PG     G+ G   P G     V 
Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443

Query: 557 GKGGKPQFGL-GELSAHATP 575
            KG     GL G L +   P
Sbjct: 444 RKGPPGDHGLPGYLGSPGIP 463



 Score =  178 bits (452), Expect = 1e-44
 Identities = 115/281 (40%), Positives = 134/281 (47%), Gaps = 62/281 (22%)

Query: 338 DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
           D+G+   DG  GE+G +G  GPPG PG  G  G  G PGP+G   P G PG+PG+ G +G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQG---PKGFPGLPGLTGSKG 91

Query: 398 PSGLAGKPGVPGERGLPGAHGPPGP---------TGPKGEPGFTGRPGG---PGVAGALG 445
             G++G PG  G  GLPG  G  GP         +G KGE GF G PG    PG+ GA G
Sbjct: 92  VRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151

Query: 446 QKGDLGL--------------PGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGP 491
            KG  G               PG PG  GP G+PG  G  GP+GP G PG  G PG  GP
Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGP 211

Query: 492 PGE---------GRAGEPGTAGPTGPPGVPGSPGIT-----------------GPPGPPG 525
            G          G  GE G  G TGPPG PG+  +T                 G  G PG
Sbjct: 212 RGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPG 271

Query: 526 PPGPPGAPGAF--DETGIAGLHLPNGGVEGAVLGKGGKPQF 564
           PPGP G PG     E G  G    + G++G   GK G P F
Sbjct: 272 PPGPSGLPGESYGSEKGAPG----DPGLQGKP-GKDGVPGF 307



 Score =  154 bits (390), Expect = 2e-37
 Identities = 94/227 (41%), Positives = 114/227 (50%), Gaps = 11/227 (4%)

Query: 373 GPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFT 432
           G  G KGE G  GPPG PG +G  GP GL G  G  G  GLPG  G  G  G  G PGF+
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 433 GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP 492
           G PG PG  G  G  G +G+PG  G +G  G PGL G  G  G  G  GLKG+ G P   
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 493 GE---GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
            +      G+PG  G  GP G+PG PG    PGP GPPGP   PG F   G  G   P G
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGF---PGPVGPPGP---PGFFGFPGAMGPRGPKG 216

Query: 550 GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDR 596
            +   V+G  G  + G+  L+    P  T ++T   P +   +K ++
Sbjct: 217 HMGERVIGHKG--ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEK 261


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  423 bits (1087), Expect = e-118
 Identities = 252/551 (45%), Positives = 285/551 (51%), Gaps = 67/551 (12%)

Query: 46   PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GK 104
            P   G +GPP  +G    +  P  +      G PGPPG PG  G  G PG PG  G  G 
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAI------GPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 105  PGLHGQPGPAGPPGFSRM----GKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160
            PG  G+ G  G PG S +    G  G PGL G  G PG+ G RG PG+ G +GL+G PGP
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 161  PGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG----VGQPGLP 216
             G PGP G       G+ G PG PG +G PG  G  G PG +G +G  G     G+PGLP
Sbjct: 990  AGPPGPRGDL-----GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLP 1044

Query: 217  GAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPG 276
            G  G  G  G PG       G PG  G PG PGD G+ G  G PGP G  G  GP+G PG
Sbjct: 1045 GIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 277  VDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY-GMPGLPGP---KGDRGPAGV 332
                G PG  G PGP G  G KG  G  GPPG+ GP G  G PG PGP   +GD+G  G+
Sbjct: 1105 --SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI 1162

Query: 333  PGLLGDRGE-------PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385
            PG  G++GE       PG  G PG QG +G  G PG PG  G  G  G  GP+G  G  G
Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222

Query: 386  PPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGP-----KGEPGFTGRPGG--- 437
             PG PG+ G   P G  G  G PG RG PGA GPPGP G      KG+ G  G PG    
Sbjct: 1223 FPGPPGLPGAIIP-GQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281

Query: 438  PGVAGALGQKGDLGLPGQPGLRGPSGIPGLQG------------------PAGPIGPQGL 479
            PG AG +G  G LG PG PGL GP G PG QG                  P GPIGP+G 
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGP 1341

Query: 480  PGLKGEPG------LPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA 532
            PG++G+PG      LPG PG  G  GEPG  G  GPPG PG+ G  GP G PG  G PG 
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGT 1401

Query: 533  PGAFDETGIAG 543
            PG   E G  G
Sbjct: 1402 PGPAGEKGNKG 1412



 Score =  411 bits (1056), Expect = e-114
 Identities = 273/643 (42%), Positives = 316/643 (49%), Gaps = 93/643 (14%)

Query: 45   QPMQKGPVGPPFREG-KGQYLEMPLPLLPMDLKGE---------PGPPGKPGPRGPPGPP 94
            QP +KG  G P   G KG    +P P   + L GE         PG PG PGP GP GPP
Sbjct: 561  QPGRKGLDGIPGTPGVKG----LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616

Query: 95   GF--PGKPGM----GKPGLHGQPGPAGPPGFSRM-----GKAGPPGLPGKVGPPGQPGLR 143
            G+   G+PG+    G PG  G PG AGP G   +     G  GPPG PG  GP G PG+ 
Sbjct: 617  GYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIP 676

Query: 144  GEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRG 203
            G  G  GD GL GP G PG+PG      PG  G QG PG  G  G PG  GEPG PG  G
Sbjct: 677  GSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPG 736

Query: 204  LKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAG-LGKPGLDGLPGAPGDKGESGPPGVPGP 262
            L G  G     +PG PG  G PG  G  G  G +G PGL GLPG PG++G      + GP
Sbjct: 737  LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG------LDGP 790

Query: 263  RGEPGAVGP---KGPPGVDGVGVPGAAGLP---GPQGPSGAKGEPGTRGPPGLIG----- 311
            RG+PG  GP   +GPPG    G  GA GLP   G +G  G +G+ G +G PG+ G     
Sbjct: 791  RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 312  -PTGYGMPGLPGPKGDRGP---AGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG 367
             P   G PG+PG +G+ GP    G PG  G  G PGEDG  G  G  G  GPPG PG+ G
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910

Query: 368  LP------------GRRGPPGPKGEAG----PG-----------GPPGVPGIRGDQGPSG 400
             P            G+RG PG KGE G    PG           G PG+ G  G+ G  G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 401  LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460
              G PG+PG +GL G  GP GP GP+G+ G TG PG PG+ G  G  G++G+PG  G RG
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 461  PSGIPGLQGPAGPIGPQGLPGLKGEPGL-----PGPPG-EGRAGEPGTAGPTGPPGVPGS 514
              G PG  G  G  G  GL G KGEPG      PGPPG  G  G PG  G  G  G PG 
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 515  PGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHAT 574
            PG  GP GP G PG PG+PG   + G  G  L   G++G            LG       
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHG-DLGFKGIKGL-----------LGPPGIRGP 1138

Query: 575  PAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVG 617
            P       SP P  G+     R    G +G    TG+   P G
Sbjct: 1139 PGLPGFPGSPGP-MGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180



 Score =  402 bits (1033), Expect = e-112
 Identities = 288/732 (39%), Positives = 332/732 (45%), Gaps = 200/732 (27%)

Query: 24   PRASSGGGAGGAAGYAPVKY--IQPMQ--KGPVGPPFREGKGQYLEMPLPLLPMDLKGEP 79
            P +    G  G  GY P     +Q  Q   G  GPP   G    L +  P+        P
Sbjct: 604  PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV--------P 655

Query: 80   GPPGKPGPRGPPGPPGFPGKPG-MGKPGLHGQPGPAGPPGFSRMGKAGPPG--------- 129
            GPPG PGP G PGP G PG PG +GK G  G PGP G PG   +G  GPPG         
Sbjct: 656  GPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPG 715

Query: 130  ------LPGKVGPPGQPGLRGEPGIRGDQGLRGP--PGPPGLPGPSGIT----------- 170
                   PGK+G PG PG  G PG +G+  +  P  PG PG PG  G +           
Sbjct: 716  TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 171  --IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGA--- 224
              +PG PG +G+ GP G  G+PGP GE GPPG R ++G  G  G PGL G  GQ G    
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 225  ---PGPPGLPGPAGLGKPGLDGLPGAPGDKGESGP---------PGVPGPRGE------- 265
                G PG+PG    G PG  G PG PG +GE GP         PG+ GP GE       
Sbjct: 835  TGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMM 894

Query: 266  --PGAVGPKGPPGVDGV----GVPGAAGLPGPQGPSGAKGEPGTRGPPG------LIGPT 313
              PGA+GP GPPG  G     G PG  G+ G +G  GAKGE G +G PG      +IG  
Sbjct: 895  GFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDK 954

Query: 314  GY----GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLP 369
            G     G  G PG KG+RG  G+PGL G +G PG  G PG +G  G  G PG PG  G+P
Sbjct: 955  GEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP 1014

Query: 370  G---RRGPPGPKGEAG----PG--GPPGVPGIRGDQG--------------PSGLAGKPG 406
            G     G PG KG+ G    PG  G PG+PGI G QG              P G  G PG
Sbjct: 1015 GSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG 1074

Query: 407  VPGERGL---------PGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPG 457
            +PG+ G          PG  GP GP G  G PG  G PG PG  G LG KG  GL G PG
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 458  LRGPSGIPGLQGPAGPIG----------------------------PQGLPGL------K 483
            +RGP G+PG  G  GP+G                            P+G PG       +
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194

Query: 484  GEPGLPGPPG-EGRAGEPGTAGPTG------PPGVPG-----------------SPGITG 519
            G PG PG PG +G  G+ G  GPTG      PPG+PG                 SPG  G
Sbjct: 1195 GAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254

Query: 520  PPGP-----------------PGPPGPPGA------PGAFDETGIAGLHLPNG--GVEG- 553
            PPGP                 PGP GPPG       PG     G  GL  P G  G +G 
Sbjct: 1255 PPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF 1314

Query: 554  -AVLGKGGKPQF 564
              V G+ G P F
Sbjct: 1315 PGVKGEKGNPGF 1326



 Score =  392 bits (1007), Expect = e-109
 Identities = 280/711 (39%), Positives = 320/711 (45%), Gaps = 176/711 (24%)

Query: 11  LLLLLLVLVLGCGPRASSG-----------GGAGGAAGYAPVKYIQPMQKGPVGPPFREG 59
           LLL LL+++L   P AS G            GA G  G          +KG  GPP   G
Sbjct: 12  LLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKG----------EKGFPGPPGSPG 61

Query: 60  KGQYLE---MPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGPAG 115
           +  +     +P P  P    G PG  G  G RG  G PGF G PG+ G PG  G  G  G
Sbjct: 62  QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG 121

Query: 116 PPGFS-RMGKAGPPGLPGKVGPPGQPGLRGEPGIRG--------DQGLRGPPGPPGLPGP 166
            PG S   G+ G PGLPG +G PG PG  G  G +G        +   +G PG PG PGP
Sbjct: 122 VPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGP 181

Query: 167 SGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG---VGQPGLPGAPGQGG 223
            G+     PG  G PGP G  G PG  G PG  G RG KG  G   +G  G  G  G  G
Sbjct: 182 QGL-----PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTG 236

Query: 224 APGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGP-----------RGEPGAVGPK 272
            PGPPG       G      L G  GDKG  G PG PGP           +G PG  G +
Sbjct: 237 PPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQ 296

Query: 273 GPPGVDGV-------GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY---------- 315
           G PG DGV       GV G  G PG  G  G KG+ G  GPPG  GPT Y          
Sbjct: 297 GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356

Query: 316 GMPGLPGPKGDRGP--------------------AGVPGLLGDRGEPGEDGEPGEQ---- 351
           G PG PGP+G RGP                     G PG  G +G  GE G PG+     
Sbjct: 357 GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416

Query: 352 -GPQGLGGPPGLPGSAGLPG-------RRGPPGPKGEAGPGGPPGVPGIRGDQ------- 396
            G  G  G PGLPGS G PG       R+GPPG  G  G  G PG+PG+ G +       
Sbjct: 417 PGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLC 476

Query: 397 -------GPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQ--- 446
                  GP GL G PG+ G +G+PG  G  G  G  G PG TG PG PG  GA G    
Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536

Query: 447 ----------KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG------LKGEPGLPG 490
                     +G +G+PG PGLRG  G  GL G  G  G +GLPG      L GE G  G
Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596

Query: 491 PPGE-GRAGEPGTAGPTGPP--------------GVPGSPG----------------ITG 519
           PPG+ G  G PG AGP GPP              GVPG+PG                + G
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 520 PPGPPGPP------GPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKP 562
           PPGPPGPP      GPPG PG+  + G  GL  P+G  G+ G  +G  G P
Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG--IGFPGPP 705



 Score =  355 bits (912), Expect = 6e-98
 Identities = 229/519 (44%), Positives = 261/519 (50%), Gaps = 60/519 (11%)

Query: 24   PRASSGGGAGGAAGYAPVKYI-----QPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGE 78
            P A    G  G  G + + ++     +P  KG  G P  +G      MP       LKG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGL---KGLKGL 986

Query: 79   PGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPG 138
            PGP G PGPRG  G  G PG+PG+   G+ G  G  G PG    GK G  G PG+ G PG
Sbjct: 987  PGPAGPPGPRGDLGSTGNPGEPGLR--GIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPG 1042

Query: 139  QPGLRGEPGIRGDQGLR-----GPPGP---PGLPGPSG----ITIPGKPGAQGVPGP--- 183
             PG+ G  G +G+ G       GPPGP   PGLPG  G    +  PG PG  G  GP   
Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGA 1102

Query: 184  PGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPGQGGAPGPPGLPGPAGL-GKPGL 241
            PG  G PG  G+PGP GD G KG  G+ G PG+ G PG    PG PG PGP G+ G  G 
Sbjct: 1103 PGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG---LPGFPGSPGPMGIRGDQGR 1159

Query: 242  DGLPGAPGDKGESGP-PGVPGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKG 299
            DG+PG  G+KGE+G     PGPRG PGA G KG  G  G  G+PG  G  G  GP G  G
Sbjct: 1160 DGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG 1219

Query: 300  EPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPG--------LLGDRGEPGEDGEPGEQ 351
              G  GPPGL G    G  G  GP G RG  G PG        ++G +G+ G  G PG +
Sbjct: 1220 IEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPK 1279

Query: 352  GPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGV------PGIRGDQGPSGLAGKP 405
            GP G  G  G PG  G PG  G PGP+G+ G  G PGV      PG  G  GP G  G  
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339

Query: 406  GVPGERGLPGA------HGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ---- 455
            G PG RG PG        G PGP G  GEPG  G PG PG  G LG  G  G PG+    
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 456  --PGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP 492
              PG  G  G  G +G  GP G  GLPGLKG+ G  G P
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score =  346 bits (888), Expect = 4e-95
 Identities = 217/470 (46%), Positives = 247/470 (52%), Gaps = 52/470 (11%)

Query: 23   GPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMP----LPLLP--MDL 75
            GPR   G  G  G  G   +    P   G +G P  +GK   L  P     P LP    L
Sbjct: 994  GPRGDLGSTGNPGEPGLRGI----PGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 76   KGEPGPPG-----KPGPRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPGFSRMGKAG 126
            +G+ G PG     +PGP GP G PG PG  G    MG+PG  G  GPAGP G    G  G
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAP--GSPG 1107

Query: 127  PPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG-PSGITIPGKPGAQGVPGPPG 185
             PGLPGK GP G  G +G  G+ G  G+RGPPG PG PG P  + I G  G  G+PGP G
Sbjct: 1108 SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167

Query: 186  FQGEPG----PQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGL-GKPG 240
             +GE G    P G  G PG +G KGD G   PG PG PG+ GA G  G  GP G+ G PG
Sbjct: 1168 EKGETGLLRAPPGPRGNPGAQGAKGDRGA--PGFPGLPGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 241  LDGLPGA--PGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAK 298
              GLPGA  PG  G  GPPG    RG PGA GP GPPG   +G+ G  G  G  GP G  
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPG---SRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPP 1282

Query: 299  GEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGG 358
            G  G  GPPG +G  G   PGLPGP+GD G  G PG+ G++G PG  G  G  GP G  G
Sbjct: 1283 GTAGDMGPPGRLGAPG--TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKG 1340

Query: 359  PPGL---PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPG 415
            PPG+   PG+  +    G PGP       G PG PG++G+ GP G  G  G  G RG PG
Sbjct: 1341 PPGVRGDPGTLKIISLPGSPGPP------GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 416  AHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIP 465
              G PG  GP GE G  G  G PG AG+       GLPG  G RG SG P
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGS------DGLPGLKGKRGDSGSP 1438



 Score =  255 bits (652), Expect = 9e-68
 Identities = 176/440 (40%), Positives = 202/440 (45%), Gaps = 103/440 (23%)

Query: 220 GQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG 279
           G  G  G  G PGP           PG+PG KG +GP G+PGP+G      PKG PG+ G
Sbjct: 43  GAKGEKGEKGFPGP-----------PGSPGQKGFTGPEGLPGPQG------PKGFPGLPG 85

Query: 280 V----GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG-------YGMPGLPGPKGDRG 328
           +    GV G +GLPG  G  G  G PG  GP GL+G  G        G PGLPG  G  G
Sbjct: 86  LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 329 PAGVPGLLGDRGEP-----------GEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP 377
             G  GL G +G P           G+ G PG  GPQGL GPPG PG  G PG  G  G 
Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 378 KGEAGPGGPPG-----VPGIRGDQGPSGLAGKPGVPG-----------------ERGLPG 415
            G  GP GP G     V G +G++G  GL G PG PG                 E+G  G
Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 416 AHGPPGPTGPKGEPGFT-----GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGL--- 467
           A G PGP GP G PG +     G PG PG+ G  G+ G  G PG  G++G  G PGL   
Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 468 ---QGPAGPIGPQGLPGL---------KGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSP 515
              +G  G IGP G  G          KG+ G PGPPG    G  G  GP+GPPGVPGSP
Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGP--RGARGPQGPSGPPGVPGSP 383

Query: 516 G-----ITGPPGPPG--------------PPGPPGAPGAFDETGIAGLHLPNGGVEGAVL 556
           G     + G PG PG                G PG+PG     G+ G   P G     V 
Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443

Query: 557 GKGGKPQFGL-GELSAHATP 575
            KG     GL G L +   P
Sbjct: 444 RKGPPGDHGLPGYLGSPGIP 463



 Score =  178 bits (452), Expect = 1e-44
 Identities = 115/281 (40%), Positives = 134/281 (47%), Gaps = 62/281 (22%)

Query: 338 DRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQG 397
           D+G+   DG  GE+G +G  GPPG PG  G  G  G PGP+G   P G PG+PG+ G +G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQG---PKGFPGLPGLTGSKG 91

Query: 398 PSGLAGKPGVPGERGLPGAHGPPGP---------TGPKGEPGFTGRPGG---PGVAGALG 445
             G++G PG  G  GLPG  G  GP         +G KGE GF G PG    PG+ GA G
Sbjct: 92  VRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151

Query: 446 QKGDLGL--------------PGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGP 491
            KG  G               PG PG  GP G+PG  G  GP+GP G PG  G PG  GP
Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGP 211

Query: 492 PGE---------GRAGEPGTAGPTGPPGVPGSPGIT-----------------GPPGPPG 525
            G          G  GE G  G TGPPG PG+  +T                 G  G PG
Sbjct: 212 RGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPG 271

Query: 526 PPGPPGAPGAF--DETGIAGLHLPNGGVEGAVLGKGGKPQF 564
           PPGP G PG     E G  G    + G++G   GK G P F
Sbjct: 272 PPGPSGLPGESYGSEKGAPG----DPGLQGKP-GKDGVPGF 307



 Score =  154 bits (390), Expect = 2e-37
 Identities = 94/227 (41%), Positives = 114/227 (50%), Gaps = 11/227 (4%)

Query: 373 GPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFT 432
           G  G KGE G  GPPG PG +G  GP GL G  G  G  GLPG  G  G  G  G PGF+
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 433 GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP 492
           G PG PG  G  G  G +G+PG  G +G  G PGL G  G  G  G  GLKG+ G P   
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 493 GE---GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG 549
            +      G+PG  G  GP G+PG PG    PGP GPPGP   PG F   G  G   P G
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGF---PGPVGPPGP---PGFFGFPGAMGPRGPKG 216

Query: 550 GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDR 596
            +   V+G  G  + G+  L+    P  T ++T   P +   +K ++
Sbjct: 217 HMGERVIGHKG--ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEK 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.148    0.484 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,722,368
Number of Sequences: 37866
Number of extensions: 5846548
Number of successful extensions: 269355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 808
Number of HSP's successfully gapped in prelim test: 2096
Number of HSP's that attempted gapping in prelim test: 21654
Number of HSP's gapped (non-prelim): 31745
length of query: 703
length of database: 18,247,518
effective HSP length: 109
effective length of query: 594
effective length of database: 14,120,124
effective search space: 8387353656
effective search space used: 8387353656
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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