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Search of human proteins with 122937343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
(1037 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 2397 0.0
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 994 0.0
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 899 0.0
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 616 e-176
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 279 1e-74
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 279 1e-74
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 261 2e-69
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 261 2e-69
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 255 2e-67
gi|134244285 Notch homolog 3 [Homo sapiens] 250 4e-66
gi|55770876 notch4 preproprotein [Homo sapiens] 246 6e-65
gi|148833508 notch1 preproprotein [Homo sapiens] 236 1e-61
gi|24041035 notch 2 preproprotein [Homo sapiens] 215 2e-55
gi|153946395 tenascin C precursor [Homo sapiens] 214 4e-55
gi|4557679 jagged 1 precursor [Homo sapiens] 213 6e-55
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 209 8e-54
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 209 1e-53
gi|21264602 laminin alpha 5 [Homo sapiens] 204 3e-52
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 192 1e-48
gi|122937283 6720455I24Rik homolog [Homo sapiens] 188 3e-47
gi|143770880 laminin, beta 4 [Homo sapiens] 164 4e-40
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 163 9e-40
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 163 9e-40
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 162 2e-39
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 155 2e-37
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 149 2e-35
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 146 9e-35
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 143 7e-34
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 143 1e-33
gi|219842266 usherin isoform B [Homo sapiens] 142 2e-33
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 2397 bits (6212), Expect = 0.0
Identities = 1037/1037 (100%), Positives = 1037/1037 (100%)
Query: 1 MSPPLCPLLLLAVGLRLAGTLNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCERPWE 60
MSPPLCPLLLLAVGLRLAGTLNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCERPWE
Sbjct: 1 MSPPLCPLLLLAVGLRLAGTLNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCERPWE 60
Query: 61 GPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQC 120
GPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQC
Sbjct: 61 GPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQC 120
Query: 121 QCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTP 180
QCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTP
Sbjct: 121 QCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTP 180
Query: 181 GYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGV 240
GYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGV
Sbjct: 181 GYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGV 240
Query: 241 FQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGD 300
FQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGD
Sbjct: 241 FQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGD 300
Query: 301 RCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQ 360
RCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQ
Sbjct: 301 RCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQ 360
Query: 361 APCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATS 420
APCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATS
Sbjct: 361 APCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATS 420
Query: 421 GLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVP 480
GLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVP
Sbjct: 421 GLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVP 480
Query: 481 CPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCD 540
CPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCD
Sbjct: 481 CPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCD 540
Query: 541 HSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPG 600
HSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPG
Sbjct: 541 HSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPG 600
Query: 601 FRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGEN 660
FRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGEN
Sbjct: 601 FRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGEN 660
Query: 661 CAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPET 720
CAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPET
Sbjct: 661 CAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPET 720
Query: 721 GACVCPPGHSGAPCRIGIQEPFTVMPTTPVAYNSLGAVIGIAVLGSLVVALVALFIGYRH 780
GACVCPPGHSGAPCRIGIQEPFTVMPTTPVAYNSLGAVIGIAVLGSLVVALVALFIGYRH
Sbjct: 721 GACVCPPGHSGAPCRIGIQEPFTVMPTTPVAYNSLGAVIGIAVLGSLVVALVALFIGYRH 780
Query: 781 WQKGKEHHHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPSYHTLSQCSPNPPPPNKVPG 840
WQKGKEHHHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPSYHTLSQCSPNPPPPNKVPG
Sbjct: 781 WQKGKEHHHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPSYHTLSQCSPNPPPPNKVPG 840
Query: 841 PLFASLQNPERPGGAQGHDNHTTLPADWKHRREPPPGPLDRGSSRLDRSYSYSYSNGPGP 900
PLFASLQNPERPGGAQGHDNHTTLPADWKHRREPPPGPLDRGSSRLDRSYSYSYSNGPGP
Sbjct: 841 PLFASLQNPERPGGAQGHDNHTTLPADWKHRREPPPGPLDRGSSRLDRSYSYSYSNGPGP 900
Query: 901 FYNKGLISEEELGASVASLSSENPYATIRDLPSLPGGPRESSYMEMKGPPSGSPPRQPPQ 960
FYNKGLISEEELGASVASLSSENPYATIRDLPSLPGGPRESSYMEMKGPPSGSPPRQPPQ
Sbjct: 901 FYNKGLISEEELGASVASLSSENPYATIRDLPSLPGGPRESSYMEMKGPPSGSPPRQPPQ 960
Query: 961 FWDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYD 1020
FWDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYD
Sbjct: 961 FWDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYD 1020
Query: 1021 LPPVRHPPSPPLRRQDR 1037
LPPVRHPPSPPLRRQDR
Sbjct: 1021 LPPVRHPPSPPLRRQDR 1037
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 994 bits (2570), Expect = 0.0
Identities = 496/1143 (43%), Positives = 600/1143 (52%), Gaps = 153/1143 (13%)
Query: 9 LLLAVGLRLAGTLNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCER--PWEGPHTCP 66
LLL + A LN DPN CS WES++ T +ES+ PF + C W C
Sbjct: 14 LLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNW---FKCT 70
Query: 67 QPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGW 126
+ V YRT YR KT +R++ QCC GFYES CVP CA +CVHGRC+APN CQC PGW
Sbjct: 71 RHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGW 130
Query: 127 RGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPA 186
G +CSS C WGP C C C N + C+P +G C C +G + C C G YG
Sbjct: 131 GGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGND 190
Query: 187 CQFRCQC-HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ 245
C RCQC +GA CD TG C CP TG C+ C G G C CQNGGV
Sbjct: 191 CHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVT 250
Query: 246 GSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREE 305
G CSCP GWMGT+C PCPEG G NCSQEC+CHNGG CD TGQC C+PGYTG+RC++E
Sbjct: 251 GECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDE 310
Query: 306 CPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
CPVG +G CAETC C +C+ +GACLCE GF G+RC RLCP+G YG+ C C C
Sbjct: 311 CPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPC 370
Query: 366 DREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQC 425
E++ SCHPM+GEC+C PGW+GL+CNE+C +G CQ+ C C +G C + +G C C
Sbjct: 371 HLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTC 430
Query: 426 APGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGT 485
APG+ G C++ CP TYG+NCS+RC C+N CSP+DG C CK GW +CS+ CP GT
Sbjct: 431 APGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGT 490
Query: 486 WGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGC 545
WGF CN +CQC + C+ G CTC PGW G C+LPC G +G CA RCDC H+DGC
Sbjct: 491 WGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGC 550
Query: 546 DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPS 605
P G C+C GW G C C EG WG NCS C CKNG +C P++G C CAPGFRG +
Sbjct: 551 HPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTT 610
Query: 606 CQRSCQPGRYGKRCVP-------------------------------------------- 621
CQR C PG YG RC
Sbjct: 611 CQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCA 670
Query: 622 --CKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS 679
C C N+ C+P + +C C GW G DCSQPCPP HWG NC TC CH+G C DG
Sbjct: 671 GICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE 730
Query: 680 CICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKC----------------HPE---- 719
C C GWTG +C + CPLG +G +C+ CQC G C H E
Sbjct: 731 CKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCP 790
Query: 720 -----------------------TGACVCPPGHSGAPCR------IGIQEPFTVMPTT-P 749
TG C C PG GA C +G + T P
Sbjct: 791 SGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLSRTSTALP 850
Query: 750 VAYNSLGAVIGIAVLGSLVVALVALFIGYRHWQKGKEHHHLAVAYSSG-RLDGSEYVMPD 808
+GA+ GI +L +V+ L+ALFI YRH QKGKE AV Y+ R+ ++Y +
Sbjct: 851 ADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMRVVNADYTISG 910
Query: 809 VPP------SYSHYYSNPSYHTLSQCSPNPPPPNK--------VPGPLFASLQNPERPGG 854
P + SHY++NPSYHTL+QC+ +P N+ LF +L+N
Sbjct: 911 TLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFVNLKNVNPGKR 970
Query: 855 AQGHDNHTTLPADWKHRREPPPGPLDR-GSSRLDRSYSYSYSNGPGPFYNKGLISEEELG 913
D TLPADWKH G L+ G+ LDRSY K L E
Sbjct: 971 GPVGDCTGTLPADWKH-----GGYLNELGAFGLDRSYMGKSL--------KDLGKNSEYN 1017
Query: 914 ASVASL-SSENPYATIRDLPSLPGGPRESSYMEMKGPPSGSPPRQPPQFWDSQRRR---- 968
+S SL SSENPYATI+D P L E Y+EMK P P S R
Sbjct: 1018 SSNCSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEV 1077
Query: 969 QPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPP 1028
+P G + L SQ P YD PKNSHIP HYDL PVR
Sbjct: 1078 EPTVSVVQGVFSNNGRL--------SQDP---------YDLPKNSHIPCHYDLLPVRDSS 1120
Query: 1029 SPP 1031
S P
Sbjct: 1121 SSP 1123
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 899 bits (2323), Expect = 0.0
Identities = 394/863 (45%), Positives = 486/863 (56%), Gaps = 101/863 (11%)
Query: 21 LNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCER--PWEGPHTCPQPTVVYRTVYRQ 78
LNP DPN CS WES+ T +ES++ PF + C W C + + Y+T YR+
Sbjct: 20 LNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNW---FKCTRHRISYKTAYRR 76
Query: 79 VVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPG 138
++T +R+R QCC G+YES FC+PLC +ECVHGRCV+P+ C C PGW G DCSS C
Sbjct: 77 GLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSD 136
Query: 139 MWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC-HGAP 197
WGP C C C N + C+P +G C C +G + C + C PG +G CQ CQC HGA
Sbjct: 137 HWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGAS 196
Query: 198 CDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGT 257
CDP+ G C C TG C+ C G+ G C CQNGG G C+CPPGW G
Sbjct: 197 CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGA 256
Query: 258 ICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAE 317
+C+ PCP G G NCSQ+C CH+GG CD TGQC C GY GDRC+EECP G FG C++
Sbjct: 257 VCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQ 316
Query: 318 TCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMN 377
CDC +C P GAC CE G+ G RC +RLCP+G +G C PC CD ++++SCHP+
Sbjct: 317 HCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVT 376
Query: 378 GECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL 437
G C+C PGW+G HCNESCP +G GCQ C C +G C + +G C CAPG+ G CA
Sbjct: 377 GACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVS 436
Query: 438 CPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCA 497
C TYG NCS+ CSC N CSP+DG C CKEGWQ +C++PCP GTWG +CN SC CA
Sbjct: 437 CAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCA 496
Query: 498 HEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAG 557
+ A CSP G+C+CTPGW G C+LPCP G FG C+ CDC H+DGCDPV G C C AG
Sbjct: 497 NGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAG 556
Query: 558 WMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGK 617
W G RC +CP G WG NCS +C+C+NGG+C PE+G+C CAPGFRGP CQR C PG YG
Sbjct: 557 WTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGH 616
Query: 618 RCVP----------------------------------------------CKCANHSFCH 631
C C CAN+ C
Sbjct: 617 GCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCS 676
Query: 632 PSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGW----- 686
P +G+C C GW G DCSQ CPPG WG C C CH+G +C +DG+C C GW
Sbjct: 677 PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFC 736
Query: 687 --------------------------------------TGHHCLEGCPLGTFGANCSQPC 708
TG HC + C GTFG C Q C
Sbjct: 737 TQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLC 796
Query: 709 QCGPGEKCHPETGACVCPPGHSGAPC---RIGIQE--PFT-VMPTTPVAYNSLGAVIGIA 762
+C C TG C C PG G C + ++E P+T + P +S+GAV GI
Sbjct: 797 ECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKISPALGAERHSVGAVTGIM 856
Query: 763 VLGSLVVALVALFIGYRHWQKGK 785
+L L+V L+ LF +R QK K
Sbjct: 857 LLLFLIVVLLGLFAWHRRRQKEK 879
Score = 68.6 bits (166), Expect = 3e-11
Identities = 50/128 (39%), Positives = 60/128 (46%), Gaps = 16/128 (12%)
Query: 904 KGLISEEELGASVASL-SSENPYATIRDLPSLPGGPRESSYMEMKGPPS-GSPPRQPPQF 961
K + E +S SL SSENPYATI+D P L ESSY+EMK P GSP P
Sbjct: 922 KDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPESSYVEMKSPVHMGSPYTDVPSL 981
Query: 962 WDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYDL 1021
S + YE + ++ G YD P+NSHIPGHYDL
Sbjct: 982 STSNKN----------IYEVEPTVSVVQEGCGHNSSYIQNA----YDLPRNSHIPGHYDL 1027
Query: 1022 PPVRHPPS 1029
PVR P+
Sbjct: 1028 LPVRQSPA 1035
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 616 bits (1588), Expect = e-176
Identities = 278/664 (41%), Positives = 334/664 (50%), Gaps = 22/664 (3%)
Query: 90 CCHGFYESR-------GFCVPLCAQECV---HGRC-VAPNQCQCVPGWRGDDCSSECAPG 138
C GF SR G+ P C C G C A C C PGW G C C G
Sbjct: 804 CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTG 863
Query: 139 MWGPQCDKPCSCG-NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC-HGA 196
WGP C PC+C + SCD SG+C C +G P C Q C G++GP C+ RCQC HGA
Sbjct: 864 HWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGA 923
Query: 197 PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMG 256
CD +GAC CPA G C+ +C G G C S +C G GSC CP G G
Sbjct: 924 ACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRG 983
Query: 257 TICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCA 316
C+ CP +G NCSQ C C NG CD GQC CAPG+ G C + CP G +G +C
Sbjct: 984 PRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR 1043
Query: 317 ETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCP-DGFYGLSCQAPCTCDREHSLSCHP 375
+C C C P +G C C G+ G C P D G C + C P
Sbjct: 1044 HSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCL----NGGLCDP 1099
Query: 376 MNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCA 435
G C C GW G C C + G C + C C G C +G C+C PG+TG C
Sbjct: 1100 HTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE 1159
Query: 436 SLCPPDTYGVNCSARCSC--ENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNAS 493
CPP ++G +C+ C C EN AC P G C C G+ +C CPPG +G C
Sbjct: 1160 QACPPGSFGEDCAQMCQCPGENP-ACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQL 1218
Query: 494 CQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQ 553
C C + C TGAC C G+ G C L CP+G+FG C C C CDPV G C
Sbjct: 1219 CGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCL 1278
Query: 554 CQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPG 613
C G G RC CP+ +GV C +TC+C+NGG C NG+C C G+ G C+ +C PG
Sbjct: 1279 CPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPG 1338
Query: 614 RYGKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT 672
RYG C + C C N+S C P+ GTC C G+ G C PCPPG G C C C HG
Sbjct: 1339 RYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAP 1398
Query: 673 CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGA 732
C P G C+CP G+ GH C GC G+FG C Q C C G C P TG C+CPPG SGA
Sbjct: 1399 CDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGA 1458
Query: 733 PCRI 736
C +
Sbjct: 1459 TCNL 1462
Score = 607 bits (1564), Expect = e-173
Identities = 266/650 (40%), Positives = 342/650 (52%), Gaps = 21/650 (3%)
Query: 103 PLCAQECVHGRCVAPN---------QCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNN 153
P C++EC +CV P+ C C G+RG+ C +EC G +GP C + C+C
Sbjct: 648 PGCSEEC---QCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVG 704
Query: 154 SSCDPKSGVCS--CPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAER 211
+CD SG C CP+G Q +C Q C G +G C C C GAPC TG C CP R
Sbjct: 705 VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGR 764
Query: 212 TGPSCDVSCSQGTSGFFCPST-HSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP 270
TG C+ C +G G C +CQ+ G+C C PG++G+ C CP G++GP
Sbjct: 765 TGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGP 824
Query: 271 NCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDC-APDARCFP 329
+C C C N G C TG C CAPG+TG C+ C G +G DC+ C+C A C
Sbjct: 825 SCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDA 884
Query: 330 ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGL 389
+G CLCE G+ G RC ++ CP G +G C+ C C +H +C ++G C+C GW G
Sbjct: 885 ISGLCLCEAGYVGPRC-EQQCPQGHFGPGCEQRCQC--QHGAACDHVSGACTCPAGWRGT 941
Query: 390 HCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSA 449
C +CP G C+ C C G C A +G C C G GP CA CP TYG NCS
Sbjct: 942 FCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQ 1001
Query: 450 RCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGAC 509
C+C N +C P+ G+C C GW +C CP G +G +C SC C + C P +G C
Sbjct: 1002 ACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHC 1061
Query: 510 TCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPE 569
C GW G C+ C GC C + CDP GRC C AGW G +C C
Sbjct: 1062 ACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLR 1121
Query: 570 GLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVP-CKCANHS 628
G +G C+ C+C G C G C C PGF G C+++C PG +G+ C C+C +
Sbjct: 1122 GWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGEN 1181
Query: 629 -FCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWT 687
CHP+ GTC C AG+ GP C Q CPPG +G C Q C C +GG+C G+C CP G+
Sbjct: 1182 PACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
Query: 688 GHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIG 737
G C CP G FG NC+ C CG G C P TG C+CPPG +G C G
Sbjct: 1242 GTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERG 1291
Score = 593 bits (1529), Expect = e-169
Identities = 278/695 (40%), Positives = 334/695 (48%), Gaps = 60/695 (8%)
Query: 96 ESRGFCVPLCAQECVHGRC--VAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNN 153
+S G L +C +G + + C C GW G C+ C P +G C CSC N
Sbjct: 514 DSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG 573
Query: 154 SSCDPKSGVCSCPSGLQPPNCLQPCTPGYY------------------------------ 183
+CD +G C CP G+ NC C GYY
Sbjct: 574 GTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLY 633
Query: 184 -------------GPACQFRCQC---HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGF 227
GP C CQC H CD + G+C C A G C C G G
Sbjct: 634 GRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGP 693
Query: 228 FCPSTHSCQNGGVFQTPQGSCS--CPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCD 285
C +C G + G C CP G+ G C CP G G NCS C C G C
Sbjct: 694 GCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCH 752
Query: 286 RFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCD-CAPDARCFPANGACLCEHGFTGDR 344
TGQCRC PG TG+ C +CP GR+G C E C C ARC P GACLC GF G R
Sbjct: 753 GVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSR 812
Query: 345 CTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGC 404
C D +CP G+YG SCQ C+C + CHP G CSC PGW G C +C GP C
Sbjct: 813 CQD-VCPAGWYGPSCQTRCSCANDG--HCHPATGHCSCAPGWTGFSCQRACDTGHWGPDC 869
Query: 405 QEHCLCLHG-GVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPID 463
C C G G C A SGLC C GY GP C CP +G C RC C++ AC +
Sbjct: 870 SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVS 929
Query: 464 GECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLP 523
G C C GW+ C CP G +G C ++C C A C G+C C G G C
Sbjct: 930 GACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAET 989
Query: 524 CPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCK 583
CP +G C+ C C + CDPVHG+C C GWMG C +CP GL+G NC ++C C+
Sbjct: 990 CPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQ 1049
Query: 584 NGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPC-KCANHSFCHPSNGTCYCLAG 642
NGGTC P +G+C C G+ G +C++ C P C C N C P G C C AG
Sbjct: 1050 NGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAG 1109
Query: 643 WTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGA 702
WTG C PC G +GE CAQ C C G CH G+C CP G+TG C + CP G+FG
Sbjct: 1110 WTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGE 1169
Query: 703 NCSQPCQCGPGEK--CHPETGACVCPPGHSGAPCR 735
+C+Q CQC PGE CHP TG C C G+ G C+
Sbjct: 1170 DCAQMCQC-PGENPACHPATGTCSCAAGYHGPSCQ 1203
Score = 499 bits (1286), Expect = e-141
Identities = 236/651 (36%), Positives = 292/651 (44%), Gaps = 97/651 (14%)
Query: 178 CTPGYYGPACQFRCQ-C-HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSC 235
C +G C C C +G C C CP TG C+ +C T G C + SC
Sbjct: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570
Query: 236 QNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAP 295
QNGG + G+C CPPG GT C CP+G++G +C ++C C N G C R G C C P
Sbjct: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDP 630
Query: 296 GYTGDRCREECPVGRFGQDCAETCDCAP--DARCFPANGACLCEHGFTGDRC-------- 345
G G C CP FG C+E C C C +G+C C+ GF G+RC
Sbjct: 631 GLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY 690
Query: 346 ------------------------------------TDRLCPDGFYGLSCQAPCTCDREH 369
+ CP G +G++C + C+C
Sbjct: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG--- 747
Query: 370 SLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHC-LCLHGGVCQATSGLCQCAPG 428
CH + G+C C PG G C CP+ G GCQE C C H C +G C C PG
Sbjct: 748 GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPG 807
Query: 429 YTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGF 488
+ G C +CP YG +C RCSC N C P G C C GW +C C G WG
Sbjct: 808 FVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP 867
Query: 489 SCNASCQC-AHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDP 547
C+ C C A C +G C C G+ G C+ CP+G FG GC RC C H CD
Sbjct: 868 DCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDH 927
Query: 548 VHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQ 607
V G C C AGW G C +CP G +G++C + C C G C NG+C+C G RGP C
Sbjct: 928 VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA 987
Query: 608 RSCQPGRYGKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQ 666
+C YG C C C N + C P +G C+C GW GP C Q CP G +G+NC +C
Sbjct: 988 ETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL 1047
Query: 667 CHHGGT-------------------------------------------CHPQDGSCICP 683
C +GGT C P G C+CP
Sbjct: 1048 CQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCP 1107
Query: 684 LGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPC 734
GWTG C C G FG C+Q C C PG CH TGAC CPPG +G+ C
Sbjct: 1108 AGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC 1158
Score = 490 bits (1261), Expect = e-138
Identities = 248/662 (37%), Positives = 308/662 (46%), Gaps = 42/662 (6%)
Query: 103 PLCAQECVHGRCVAPNQCQCVPGWR--GDDCS----SECAPGMWGPQCDKPCSCGNNSSC 156
P C Q C + +C C G+R D C ECA G C+ C+ N +
Sbjct: 380 PCCQQVCTNNP--GGYECGCYAGYRLSADGCGCEDVDECASSRGG--CEHHCT--NLAG- 432
Query: 157 DPKSGVCSCPSGLQPPNCLQPCTP------------GYYGPACQFRCQCHGAPC---DPQ 201
S CSC +G + + C+P + P P D
Sbjct: 433 ---SFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDD 489
Query: 202 TGACFCPAERTGPSCDVS---CSQGTSGFFCPST-HSCQNGGVFQTPQGSCSCPPGWMGT 257
GA AE G C + G C T C+NGG C CP GW G
Sbjct: 490 VGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGL 549
Query: 258 ICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAE 317
IC+ CP G NCS C C NGG CD TG CRC PG +G C + CP G +G+ C +
Sbjct: 550 ICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRK 609
Query: 318 TCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMN 377
C+CA RC GACLC+ G G C CP +G C C C + H+ SC +
Sbjct: 610 KCNCANRGRCHRLYGACLCDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQPHTQSCDKRD 668
Query: 378 GECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLC--QCAPGYTGPHCA 435
G CSC G+ G C C GPGC + C C G C + SG C +C G+ G C
Sbjct: 669 GSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG 728
Query: 436 SLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASC- 494
CP T+GVNCS+ CSC A C + G+C C G +C CP G WG C C
Sbjct: 729 QECPVGTFGVNCSSSCSCGGA-PCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICP 787
Query: 495 QCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQC 554
C H A C P+TGAC C PG+ G+ CQ CP G +G C +RC C + C P G C C
Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSC 847
Query: 555 QAGWMGARCHLSCPEGLWGVNCSNTCTCKNG-GTCLPENGNCVCAPGFRGPSCQRSCQPG 613
GW G C +C G WG +CS+ C C G G+C +G C+C G+ GP C++ C G
Sbjct: 848 APGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQG 907
Query: 614 RYGKRCVP-CKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT 672
+G C C+C + + C +G C C AGW G C CP G +G +C C C G
Sbjct: 908 HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAA 967
Query: 673 CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGA 732
C +GSC+CP G G C E CP T+G NCSQ C C G C P G C C PG G
Sbjct: 968 CDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGP 1027
Query: 733 PC 734
C
Sbjct: 1028 SC 1029
Score = 474 bits (1219), Expect = e-133
Identities = 213/511 (41%), Positives = 258/511 (50%), Gaps = 9/511 (1%)
Query: 101 CVPLCAQECVHGRCVAP--NQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDP 158
C CA C +G P QC C PGW G C C G++G C C C N +CDP
Sbjct: 999 CSQACA--CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDP 1056
Query: 159 KSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC-HGAPCDPQTGACFCPAERTGPSCD 217
SG C+CP G C + C P C+ C +G CDP TG C CPA TG C
Sbjct: 1057 VSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQ 1116
Query: 218 VSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECR 277
C +G G C SC G G+C CPPG+ G+ C CP G G +C+Q C+
Sbjct: 1117 SPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQ 1176
Query: 278 CHNGG-LCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLC 336
C C TG C CA GY G C++ CP GR+G C + C C C A GAC C
Sbjct: 1177 CPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRC 1236
Query: 337 EHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCP 396
GF G C + CP G +G +C C C + +C P+ G C C PG AG+ C CP
Sbjct: 1237 PTGFLGTDC-NLTCPQGRFGPNCTHVCGCGQ--GAACDPVTGTCLCPPGRAGVRCERGCP 1293
Query: 397 QDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENA 456
Q+ G GC+ C C +GG+C A++G C C G+TG HC CPP YG C CSC N
Sbjct: 1294 QNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNN 1353
Query: 457 IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWH 516
C P G C C G+ C PCPPG G C C C H A C P +G C C G+H
Sbjct: 1354 STCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFH 1413
Query: 517 GAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNC 576
G C+ C G FGEGC RCDCD CDPV G C C G GA C+L C G +G +C
Sbjct: 1414 GHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSC 1473
Query: 577 SNTCTCKNGGTCLPENGNCVCAPGFRGPSCQ 607
+ C C G C P +G C C G+ GP+C+
Sbjct: 1474 TLHCDCGGGADCDPVSGQCHCVDGYMGPTCR 1504
Score = 347 bits (890), Expect = 3e-95
Identities = 249/842 (29%), Positives = 315/842 (37%), Gaps = 151/842 (17%)
Query: 21 LNPSDPNTCSFWESFTTTTKESHSRPFS-LLPSEPCERPWEGPHTCPQPTVVYRTVYRQV 79
L P P+ C+ E ++ + S +P W+ + VY YRQV
Sbjct: 40 LQPGMPHVCAEQELTLVGRRQPCVQALSHTVPVWKAGCGWQAWCVGHERRTVYYMGYRQV 99
Query: 80 VKTDHRQRLQCCHGFYES---RGFCVPLC-AQECVHG-RCV--APNQCQCVPGWRGDDCS 132
T+ R L+CC G+ + G C A C HG RCV + C C PG++G C
Sbjct: 100 YTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQ 159
Query: 133 ---SECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQ----PPNCL--QPCTPGYY 183
EC G C + P S +C C G + CL C G
Sbjct: 160 YDVDECRTHNGG--------CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNG 211
Query: 184 GPACQF----------RCQCHG--------------APCDPQTGACF--CPAERTGPSCD 217
G CQ RCQC +PC + G+C C R C+
Sbjct: 212 G--CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCE 269
Query: 218 --VSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQ- 274
V G C C G+ Q G C G +C G G C +
Sbjct: 270 CHVGYQLAADGKACEDVDECA-AGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRI 327
Query: 275 ------ECRCHNGGL---CDRFTGQ--CRCAPGYTGDR----------------CREECP 307
C +NGG C + C C GY D C++ C
Sbjct: 328 EMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCT 387
Query: 308 VGRFGQDC---------AETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLS 358
G +C A+ C C C + G C EH CT+ G + S
Sbjct: 388 NNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC--EH-----HCTNLA---GSFQCS 437
Query: 359 CQAPCTCDREHSLSCHPMNGECSCLPGW-------------------------AGLHCNE 393
C+A E C P+ L G G E
Sbjct: 438 CEAGYRL-HEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEE 496
Query: 394 S-------------CPQDTHGPGCQEHCL-CLHGGVCQATSGLCQCAPGYTGPHCASLCP 439
+ C D+ G C C C +GG C C C G+TG C CP
Sbjct: 497 AELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCP 556
Query: 440 PDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHE 499
PDT+G NCS CSC+N C + G C C G NC CP G +G C C CA+
Sbjct: 557 PDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANR 616
Query: 500 AVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDC--DHSDGCDPVHGRCQCQAG 557
C GAC C PG +G C L CP FG GC+ C C H+ CD G C C+AG
Sbjct: 617 GRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG 676
Query: 558 WMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNC--VCAPGFRGPSCQRSCQPGRY 615
+ G RC C G +G C CTC G C +G C C GF+G C + C G +
Sbjct: 677 FRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTF 736
Query: 616 GKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTC-QCHHGGTC 673
G C C C + CH G C C G TG DC CP G WG C + C C H C
Sbjct: 737 GVNCSSSCSCGG-APCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARC 795
Query: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAP 733
P+ G+C+C G+ G C + CP G +G +C C C CHP TG C C PG +G
Sbjct: 796 DPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFS 855
Query: 734 CR 735
C+
Sbjct: 856 CQ 857
Score = 151 bits (382), Expect = 3e-36
Identities = 149/566 (26%), Positives = 199/566 (35%), Gaps = 115/566 (20%)
Query: 250 CPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQ-CRCAPGYTGDRCR---EE 305
C GWM P EG CS C +GG C + Q C C PG+ G RC+ +E
Sbjct: 110 CCRGWM----QQPDEEGCLSAECSASL-CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDE 164
Query: 306 CPVGRFG--QDCAET-----CDCAPDARCFPANGACL-----------CEHG-----FTG 342
C G C T C+C P R + CL C+H T
Sbjct: 165 CRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITR 224
Query: 343 DRCTDRLCPDGFY----GLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQD 398
RC C GF G C C + H C + G A C+
Sbjct: 225 HRCQ---CRPGFQLQEDGRHCVRRSPCANRNGSCMH----RCQVVRGLARCECHVGYQLA 277
Query: 399 THGPGCQE--HCL-----CLHGGVCQATSGLCQCAPGYT----GPHCASL-------CPP 440
G C++ C C HG + S C C GY G C + C
Sbjct: 278 ADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 337
Query: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEA 500
+ G CS CS +A P+ C C G++ C C S C
Sbjct: 338 NNGG--CSHGCSHTSA---GPL---CTCPRGYELDTDQRTCIDVD---DCADSPCCQQVC 386
Query: 501 VCSPQTGACTCTPGWH----GAHCQLPCPKGQFGEGC---------ASRCDCD-----HS 542
+P C C G+ G C+ GC + +C C+ H
Sbjct: 387 TNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHE 446
Query: 543 D--GCDPVHGRCQCQAG---WMGARCHLSCPEGLW-------GVNCSNTCTCKNGGTCLP 590
D GC P+ G ++ H++ + V G L
Sbjct: 447 DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLT 506
Query: 591 ENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQ 650
E VC G C +C C N C C C GWTG C++
Sbjct: 507 EK--FVCLDDSFGHDCSLTCDD-----------CRNGGTCLLGLDGCDCPEGWTGLICNE 553
Query: 651 PCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQC 710
CPP +G+NC+ +C C +GGTC G+C CP G +G +C +GCP G +G +C + C C
Sbjct: 554 TCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNC 613
Query: 711 GPGEKCHPETGACVCPPGHSGAPCRI 736
+CH GAC+C PG G C +
Sbjct: 614 ANRGRCHRLYGACLCDPGLYGRFCHL 639
Score = 120 bits (302), Expect = 5e-27
Identities = 135/526 (25%), Positives = 169/526 (32%), Gaps = 117/526 (22%)
Query: 292 RCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA-CLCEHGFTGDRCTDRLC 350
RC G+ E C +C+ + C RC P + C C GF G RC +
Sbjct: 109 RCCRGWMQQPDEEGC----LSAECSASL-CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVD 163
Query: 351 PDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNE-------SCPQDTHGPG 403
+ CQ C P + C C PG+ LH + SC G
Sbjct: 164 ECRTHNGGCQHRCVNT--------PGSYLCECKPGFR-LHTDSRTCLAINSCALGNGG-- 212
Query: 404 CQEHCLCLHGGVCQATSGLCQCAPGYT----GPHCASLCPPDTYGVNCSARCSCENAIAC 459
CQ HC+ L T CQC PG+ G HC P +C RC +A
Sbjct: 213 CQHHCVQL-----TITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLA- 266
Query: 460 SPIDGECVCKEGWQRG-----------------NCSVPCPPGTWGFSCNASCQCAHEA-- 500
C C G+Q C+ C F C C +E
Sbjct: 267 -----RCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKC--VCHAGYELGA 319
Query: 501 --------------VCSPQTGACT--CTPGWHGAHCQLPCPKGQFGEGCASRC----DCD 540
C G C+ C+ G C CP+G + C DC
Sbjct: 320 DGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCT--CPRGYELDTDQRTCIDVDDCA 377
Query: 541 HSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNG-GTCLPENGNCVCAP 599
S C V C G C+ G C + C + G C +C
Sbjct: 378 DSPCCQQV---CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC---EHHCTNLA 431
Query: 600 GFRGPSCQRSCQPGRYGKRCVPCK------CANHSFCHPSNGTCYCLAGW--------TG 645
G SC+ + + C P + F P G
Sbjct: 432 GSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVG 491
Query: 646 PDCSQP-------------CPPGHWGENCAQTCQ-CHHGGTCHPQDGSCICPLGWTGHHC 691
D + C +G +C+ TC C +GGTC C CP GWTG C
Sbjct: 492 ADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLIC 551
Query: 692 LEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIG 737
E CP TFG NCS C C G C TGAC CPPG SG C G
Sbjct: 552 NETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDG 597
Score = 35.0 bits (79), Expect = 0.37
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 682 CPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGA-CVCPPGHSGAPCRIGIQE 740
C GW EGC A CS C G +C P + C CPPG G C+ + E
Sbjct: 110 CCRGWMQQPDEEGC----LSAECSASL-CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDE 164
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 279 bits (713), Expect = 1e-74
Identities = 149/401 (37%), Positives = 183/401 (45%), Gaps = 50/401 (12%)
Query: 240 VFQTPQGSCSCPPGWM--GTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGY 297
V +P C GW C++P EG P+ C +C + G CRC PG+
Sbjct: 31 VASSPSAELQCCAGWRQKDQECTIPICEG---PDA-----CQKDEVCVK-PGLCRCKPGF 81
Query: 298 TGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRL-------- 349
G C CP +G DC E+C C P +C PA GAC C+ G RC
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRC 141
Query: 350 --------CPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN-------ES 394
C G++ +C+ PC C+ + C G C C PGW G C+
Sbjct: 142 DPATGVCHCEPGWWSSTCRRPCQCNTA-AARCEQATGACVCKPGWWGRRCSFRCNCHGSP 200
Query: 395 CPQDTH---------GPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGV 445
C QD+ GP CQ+ C C+ G C A SG C C PG+ G C CP ++GV
Sbjct: 201 CEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGV 259
Query: 446 NCSARCS-CENAIACSPIDGECV-CKEGWQRGNCSVPCPPGTWGFSCNASC-QCAHEAVC 502
C+ C C++ CSP G C C+ GW C PC PGT+G SC C C H C
Sbjct: 260 QCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEAC 319
Query: 503 SPQTGACT-CTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
P TG C C PGW G C+ PCP G FGE C S C CD V G C C AG+ G
Sbjct: 320 EPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGP 379
Query: 562 RCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFR 602
C+ SCP G G NCS C C G C P +G+C G R
Sbjct: 380 SCNASCPAGFHGNNCSVPCECPE-GLCHPVSGSCQPGSGSR 419
Score = 271 bits (692), Expect = 3e-72
Identities = 139/395 (35%), Positives = 173/395 (43%), Gaps = 48/395 (12%)
Query: 368 EHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAP 427
+H + E C GW Q+ P C+ C VC GLC+C P
Sbjct: 27 QHVCVASSPSAELQCCAGW------RQKDQECTIPICEGPDACQKDEVC-VKPGLCRCKP 79
Query: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP----- 482
G+ G HC+S CP +G +C C C C P G C C+ C PC
Sbjct: 80 GFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG 139
Query: 483 ------------PGTWGFSCNASCQCAHEAV-CSPQTGACTCTPGWHGAHCQL------- 522
PG W +C CQC A C TGAC C PGW G C
Sbjct: 140 RCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGS 199
Query: 523 ---------PCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG 573
C G +G C +C+C C G C C G+ GARC L CP G G
Sbjct: 200 PCEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHG 258
Query: 574 VNCSNTC-TCKNGGTCLPENGNCV-CAPGFRGPSCQRSCQPGRYGKRCVP-CK-CANHSF 629
V C+++C CK+ C P+ G+C C PG+ G CQ+ C PG +G+ C C C +
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
Query: 630 CHPSNGTCY-CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTG 688
C P G C C GW GP C PCP G +GE+C TC G+C G C+C G+ G
Sbjct: 319 CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWG 378
Query: 689 HHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGAC 723
C CP G G NCS PC+C P CHP +G+C
Sbjct: 379 PSCNASCPAGFHGNNCSVPCEC-PEGLCHPVSGSC 412
Score = 250 bits (639), Expect = 4e-66
Identities = 138/398 (34%), Positives = 173/398 (43%), Gaps = 76/398 (19%)
Query: 88 LQCCHGFYESRGFC-VPLCA--QECVHGR-CVAPNQCQCVPGWRGDDCSSECAPGMWGPQ 143
LQCC G+ + C +P+C C CV P C+C PG+ G CSS C WGP
Sbjct: 39 LQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
Query: 144 CDK------------------------------PCSCGNNSSCDPKSGVCSCPSGLQPPN 173
C + PC+CG + CDP +GVC C G
Sbjct: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSST 158
Query: 174 CLQP------------------CTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPS 215
C +P C PG++G C FRC CHG+PC+ +G C C GP
Sbjct: 159 CRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPE 218
Query: 216 CDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQE 275
C C C G G C+CPPG+ G C LPCP G HG C+
Sbjct: 219 CQQQC-------------ECVRGRC-SAASGECTCPPGFRGARCELPCPAGSHGVQCAHS 264
Query: 276 C-RCHNGGLCDRFTGQCR-CAPGYTGDRCREECPVGRFGQDCAETC-DCAPDARCFPANG 332
C RC + C TG C C PG+ G +C++ C G FG+ C + C C C P G
Sbjct: 265 CGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324
Query: 333 AC-LCEHGFTGDRCTDRLCPDGFYGLSCQAPC-TCDREHSLSCHPMNGECSCLPGWAGLH 390
C C+ G+ G RC D CP G +G C + C TC + SC + G+C C G+ G
Sbjct: 325 HCQRCDPGWLGPRCEDP-CPTGTFGEDCGSTCPTCVQG---SCDTVTGDCVCSAGYWGPS 380
Query: 391 CNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPG 428
CN SCP HG C C C G+C SG CQ G
Sbjct: 381 CNASCPAGFHGNNCSVPCECPE-GLCHPVSGSCQPGSG 417
Score = 151 bits (381), Expect = 4e-36
Identities = 85/274 (31%), Positives = 104/274 (37%), Gaps = 60/274 (21%)
Query: 484 GTWGFSCNASCQCAHEAVCSPQTGACTCTPGWH--GAHCQLPCPKGQFGEGCASRCDCDH 541
GT G + Q H V S + C GW C +P +G D
Sbjct: 16 GTQGSELDPKGQ--HVCVASSPSAELQCCAGWRQKDQECTIPICEGP---------DACQ 64
Query: 542 SDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGF 601
D G C+C+ G+ GA C CP WG +C +C C G C P G C
Sbjct: 65 KDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC------ 118
Query: 602 RGPSCQRSCQPGRYGKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCP------- 653
CQ R+G RC PC C H C P+ G C+C GW C +PC
Sbjct: 119 -------QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAAR 171
Query: 654 -----------PGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGA 702
PG WG C+ C CH G C G C C GW +G
Sbjct: 172 CEQATGACVCKPGWWGRRCSFRCNCH-GSPCEQDSGRCACRPGW-------------WGP 217
Query: 703 NCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRI 736
C Q C+C G +C +G C CPPG GA C +
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCEL 250
Score = 82.4 bits (202), Expect = 2e-15
Identities = 51/157 (32%), Positives = 61/157 (38%), Gaps = 30/157 (19%)
Query: 53 EPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHG-FYESRGFCVPLCAQECVH 111
E CE W G C QP C G F ES C C C H
Sbjct: 282 ESCEPGWNGTQ-CQQP---------------------CLPGTFGES---CEQQCPH-CRH 315
Query: 112 GRCVAPN--QCQ-CVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSG 168
G P+ CQ C PGW G C C G +G C C SCD +G C C +G
Sbjct: 316 GEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAG 375
Query: 169 LQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGAC 205
P+C C G++G C C+C C P +G+C
Sbjct: 376 YWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSC 412
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 279 bits (713), Expect = 1e-74
Identities = 149/401 (37%), Positives = 183/401 (45%), Gaps = 50/401 (12%)
Query: 240 VFQTPQGSCSCPPGWM--GTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGY 297
V +P C GW C++P EG P+ C +C + G CRC PG+
Sbjct: 31 VASSPSAELQCCAGWRQKDQECTIPICEG---PDA-----CQKDEVCVK-PGLCRCKPGF 81
Query: 298 TGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRL-------- 349
G C CP +G DC E+C C P +C PA GAC C+ G RC
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRC 141
Query: 350 --------CPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN-------ES 394
C G++ +C+ PC C+ + C G C C PGW G C+
Sbjct: 142 DPATGVCHCEPGWWSSTCRRPCQCNTA-AARCEQATGACVCKPGWWGRRCSFRCNCHGSP 200
Query: 395 CPQDTH---------GPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGV 445
C QD+ GP CQ+ C C+ G C A SG C C PG+ G C CP ++GV
Sbjct: 201 CEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGV 259
Query: 446 NCSARCS-CENAIACSPIDGECV-CKEGWQRGNCSVPCPPGTWGFSCNASC-QCAHEAVC 502
C+ C C++ CSP G C C+ GW C PC PGT+G SC C C H C
Sbjct: 260 QCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEAC 319
Query: 503 SPQTGACT-CTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
P TG C C PGW G C+ PCP G FGE C S C CD V G C C AG+ G
Sbjct: 320 EPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGP 379
Query: 562 RCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFR 602
C+ SCP G G NCS C C G C P +G+C G R
Sbjct: 380 SCNASCPAGFHGNNCSVPCECPE-GLCHPVSGSCQPGSGSR 419
Score = 271 bits (692), Expect = 3e-72
Identities = 139/395 (35%), Positives = 173/395 (43%), Gaps = 48/395 (12%)
Query: 368 EHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAP 427
+H + E C GW Q+ P C+ C VC GLC+C P
Sbjct: 27 QHVCVASSPSAELQCCAGW------RQKDQECTIPICEGPDACQKDEVC-VKPGLCRCKP 79
Query: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP----- 482
G+ G HC+S CP +G +C C C C P G C C+ C PC
Sbjct: 80 GFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG 139
Query: 483 ------------PGTWGFSCNASCQCAHEAV-CSPQTGACTCTPGWHGAHCQL------- 522
PG W +C CQC A C TGAC C PGW G C
Sbjct: 140 RCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGS 199
Query: 523 ---------PCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG 573
C G +G C +C+C C G C C G+ GARC L CP G G
Sbjct: 200 PCEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHG 258
Query: 574 VNCSNTC-TCKNGGTCLPENGNCV-CAPGFRGPSCQRSCQPGRYGKRCVP-CK-CANHSF 629
V C+++C CK+ C P+ G+C C PG+ G CQ+ C PG +G+ C C C +
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
Query: 630 CHPSNGTCY-CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTG 688
C P G C C GW GP C PCP G +GE+C TC G+C G C+C G+ G
Sbjct: 319 CEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWG 378
Query: 689 HHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGAC 723
C CP G G NCS PC+C P CHP +G+C
Sbjct: 379 PSCNASCPAGFHGNNCSVPCEC-PEGLCHPVSGSC 412
Score = 250 bits (639), Expect = 4e-66
Identities = 138/398 (34%), Positives = 173/398 (43%), Gaps = 76/398 (19%)
Query: 88 LQCCHGFYESRGFC-VPLCA--QECVHGR-CVAPNQCQCVPGWRGDDCSSECAPGMWGPQ 143
LQCC G+ + C +P+C C CV P C+C PG+ G CSS C WGP
Sbjct: 39 LQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
Query: 144 CDK------------------------------PCSCGNNSSCDPKSGVCSCPSGLQPPN 173
C + PC+CG + CDP +GVC C G
Sbjct: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSST 158
Query: 174 CLQP------------------CTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPS 215
C +P C PG++G C FRC CHG+PC+ +G C C GP
Sbjct: 159 CRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPE 218
Query: 216 CDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQE 275
C C C G G C+CPPG+ G C LPCP G HG C+
Sbjct: 219 CQQQC-------------ECVRGRC-SAASGECTCPPGFRGARCELPCPAGSHGVQCAHS 264
Query: 276 C-RCHNGGLCDRFTGQCR-CAPGYTGDRCREECPVGRFGQDCAETC-DCAPDARCFPANG 332
C RC + C TG C C PG+ G +C++ C G FG+ C + C C C P G
Sbjct: 265 CGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324
Query: 333 AC-LCEHGFTGDRCTDRLCPDGFYGLSCQAPC-TCDREHSLSCHPMNGECSCLPGWAGLH 390
C C+ G+ G RC D CP G +G C + C TC + SC + G+C C G+ G
Sbjct: 325 HCQRCDPGWLGPRCEDP-CPTGTFGEDCGSTCPTCVQG---SCDTVTGDCVCSAGYWGPS 380
Query: 391 CNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPG 428
CN SCP HG C C C G+C SG CQ G
Sbjct: 381 CNASCPAGFHGNNCSVPCECPE-GLCHPVSGSCQPGSG 417
Score = 151 bits (381), Expect = 4e-36
Identities = 85/274 (31%), Positives = 104/274 (37%), Gaps = 60/274 (21%)
Query: 484 GTWGFSCNASCQCAHEAVCSPQTGACTCTPGWH--GAHCQLPCPKGQFGEGCASRCDCDH 541
GT G + Q H V S + C GW C +P +G D
Sbjct: 16 GTQGSELDPKGQ--HVCVASSPSAELQCCAGWRQKDQECTIPICEGP---------DACQ 64
Query: 542 SDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGF 601
D G C+C+ G+ GA C CP WG +C +C C G C P G C
Sbjct: 65 KDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC------ 118
Query: 602 RGPSCQRSCQPGRYGKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCP------- 653
CQ R+G RC PC C H C P+ G C+C GW C +PC
Sbjct: 119 -------QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAAR 171
Query: 654 -----------PGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGA 702
PG WG C+ C CH G C G C C GW +G
Sbjct: 172 CEQATGACVCKPGWWGRRCSFRCNCH-GSPCEQDSGRCACRPGW-------------WGP 217
Query: 703 NCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRI 736
C Q C+C G +C +G C CPPG GA C +
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCEL 250
Score = 82.4 bits (202), Expect = 2e-15
Identities = 51/157 (32%), Positives = 61/157 (38%), Gaps = 30/157 (19%)
Query: 53 EPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHG-FYESRGFCVPLCAQECVH 111
E CE W G C QP C G F ES C C C H
Sbjct: 282 ESCEPGWNGTQ-CQQP---------------------CLPGTFGES---CEQQCPH-CRH 315
Query: 112 GRCVAPN--QCQ-CVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSG 168
G P+ CQ C PGW G C C G +G C C SCD +G C C +G
Sbjct: 316 GEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAG 375
Query: 169 LQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGAC 205
P+C C G++G C C+C C P +G+C
Sbjct: 376 YWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSC 412
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 261 bits (667), Expect = 2e-69
Identities = 135/411 (32%), Positives = 175/411 (42%), Gaps = 60/411 (14%)
Query: 249 SCPPGW--MGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREEC 306
+C GW G C + EG C +C R G+CRC GY G C +C
Sbjct: 63 TCCAGWRQQGDECGIAVCEG--------NSTCSENEVCVR-PGECRCRHGYFGANCDTKC 113
Query: 307 PVGRFGQDCAETCDCAPDARCFPANG---------------ACLCEHGFTGDRCTDRLCP 351
P +G DC E C C P +C G AC C+HG R C
Sbjct: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCE 173
Query: 352 DGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCL 411
G++G C + C C + C P G C C GW G CN C
Sbjct: 174 PGWWGAQCASACYCSA--TSRCDPQTGACLCHAGWWGRSCNNQC--------------AC 217
Query: 412 HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEG 471
+ C+ SG CQC T+G C C C C P+DG C C+ G
Sbjct: 218 NSSPCEQQSGRCQCRER-------------TFGARCDRYCQCFRG-RCHPVDGTCACEPG 263
Query: 472 WQRGNCSVPCPPGTWGFSCNASC-QCAHEAVCSPQTGAC-TCTPGWHGAHCQLPCPKGQF 529
++ C PCP G +G C C QC + C+ G C TC PGW+G C PC G +
Sbjct: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Query: 530 GEGCASRCD-CDHSDGCDPVHGRC-QCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGT 587
GEGC+ RC C C+ V G+C +C AGW+G RC C G +G +C+ C G
Sbjct: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH 383
Query: 588 CLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCY 638
C ++G C+C+PG GP C +C PG +G C + C P G C+
Sbjct: 384 CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACH 434
Score = 248 bits (633), Expect = 2e-65
Identities = 137/423 (32%), Positives = 184/423 (43%), Gaps = 55/423 (13%)
Query: 77 RQVVKTDHRQRLQCCHGFYESRGFC-VPLCA--QECVHGR-CVAPNQCQCVPGWRGDDCS 132
R V + Q CC G+ + C + +C C CV P +C+C G+ G +C
Sbjct: 51 RNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCD 110
Query: 133 SECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQ 192
++C WGP C + CSC + C+ +G C+C + +G C+ CQ
Sbjct: 111 TKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARR-------------WGARCEHACQ 157
Query: 193 CHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ-GSCSCP 251
C C P++GAC C G C +C +C +T C PQ G+C C
Sbjct: 158 CQHGTCHPRSGACRCEPGWWGAQCASAC-------YCSATSRCD-------PQTGACLCH 203
Query: 252 PGWMGTICS----------------LPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAP 295
GW G C+ C E G C + C+C G C G C C P
Sbjct: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEP 262
Query: 296 GYTGDRCREECPVGRFGQDCAETC-DCAPDARCFPANGACL-CEHGFTGDRCTDRLCPDG 353
GY G CRE CP G +G C C C C A G CL CE G+ G +C D+ C G
Sbjct: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKC-DQPCATG 321
Query: 354 FYGLSCQAPCTCDREHSLSCHPMNGECS-CLPGWAGLHCNESCPQDTHGPGCQEHCLCLH 412
FYG C C R+ +C+ + G+C+ C GW G C C T+G C C
Sbjct: 322 FYGEGCSHRCPPCRDGH-ACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCG 380
Query: 413 GGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGW 472
G C SG C C+PG GPHC CPP +G +C+ CSC C P+ G C +
Sbjct: 381 SGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHED-TCDPVTGACHLETNQ 439
Query: 473 QRG 475
++G
Sbjct: 440 RKG 442
Score = 237 bits (605), Expect = 4e-62
Identities = 204/762 (26%), Positives = 286/762 (37%), Gaps = 110/762 (14%)
Query: 359 CQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQA 418
C+ TC E+ + P GEC C G+ G +C+ CP+ GP C+E C C G C+
Sbjct: 80 CEGNSTCS-ENEVCVRP--GECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCED 136
Query: 419 TSGLCQCAPGYTGPHC----------------ASLCPPDTYGVNCSARCSCENAIACSPI 462
+G C C G C A C P +G C++ C C C P
Sbjct: 137 VTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQ 196
Query: 463 DGECVCKEGW------------------QRGNCSVPCPPGTWGFSCNASCQCAHEAVCSP 504
G C+C GW Q G C C T+G C+ CQC C P
Sbjct: 197 TGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQ--CRERTFGARCDRYCQC-FRGRCHP 253
Query: 505 QTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC-DCDHSDGCDPVHGRC-QCQAGWMGAR 562
G C C PG+ G +C+ PCP G +G GC RC C C GRC C+ GW G +
Sbjct: 254 VDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTK 313
Query: 563 CHLSCPEGLWGVNCSNTCT-CKNGGTCLPENGNCV-CAPGFRGPSCQRSCQPGRYGKRCV 620
C C G +G CS+ C C++G C G C C G+ G C+ C G YG+ C
Sbjct: 314 CDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCA 373
Query: 621 -PCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHG------GTC 673
C C +G C C G GP C+ CPPG G +CAQ C CH G C
Sbjct: 374 FVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGAC 433
Query: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQC---GPGEKCHPET----GACVCP 726
H + +G L C L + C C C P + P G P
Sbjct: 434 HLETNQRKGVMGAGALLVLLVCLLLSLLGCC---CACRGKDPTRRPRPRRELSLGRKKAP 490
Query: 727 PGHSGAPCRIGIQEPFTVM-----PTTPVAYNSLGAVIGIAVLG--------SLVVALVA 773
G RI ++ P + P VA++ L + + L S + A
Sbjct: 491 HRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRA 550
Query: 774 LFIGYRHWQKGKEHHHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPSYHTLSQCSPNPP 833
F + +G + V + + + +P VP P S P
Sbjct: 551 SFSSFDTTDEGPVY---CVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAIPL 607
Query: 834 PPNK--------VPGP---LFASLQNPE-RPGGAQGHDNHTTLPADWKHRREPPPGPLDR 881
P + V GP L+A + E RP A+G +L + R+ PPP P +
Sbjct: 608 PASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPATK 667
Query: 882 GS-SRLDRSYSYSYSN---GPGPFYNKGLISEEELGASVASLSS---ENPYATIRD-LPS 933
S + +S + + P P ++ S + + + S+ E+ RD P
Sbjct: 668 PKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPR 727
Query: 934 LPGGPRESSYMEMKGPPSGSPPRQPPQFWDSQRRRQPQPQRDSGTY------EQPSPLIH 987
PG P E++ + PP P RRR P + ++ + + L
Sbjct: 728 PPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSLGR 787
Query: 988 DRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPS 1029
++G+Q P PP K S P P R PP+
Sbjct: 788 AEVALGAQGPREKPAPP---QKAKRSVPPA----SPARAPPA 822
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 11/110 (10%)
Query: 632 PSNGTCYCLAGWT--GPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGH 689
P + C AGW G +C C C C + G C C G+ G
Sbjct: 57 PGSQVPTCCAGWRQQGDECGIAV--------CEGNSTCSENEVC-VRPGECRCRHGYFGA 107
Query: 690 HCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQ 739
+C CP +G +C + C C P +C TG C C GA C Q
Sbjct: 108 NCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ 157
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 261 bits (667), Expect = 2e-69
Identities = 135/411 (32%), Positives = 175/411 (42%), Gaps = 60/411 (14%)
Query: 249 SCPPGW--MGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREEC 306
+C GW G C + EG C +C R G+CRC GY G C +C
Sbjct: 63 TCCAGWRQQGDECGIAVCEG--------NSTCSENEVCVR-PGECRCRHGYFGANCDTKC 113
Query: 307 PVGRFGQDCAETCDCAPDARCFPANG---------------ACLCEHGFTGDRCTDRLCP 351
P +G DC E C C P +C G AC C+HG R C
Sbjct: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCE 173
Query: 352 DGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCL 411
G++G C + C C + C P G C C GW G CN C
Sbjct: 174 PGWWGAQCASACYCSA--TSRCDPQTGACLCHAGWWGRSCNNQC--------------AC 217
Query: 412 HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEG 471
+ C+ SG CQC T+G C C C C P+DG C C+ G
Sbjct: 218 NSSPCEQQSGRCQCRER-------------TFGARCDRYCQCFRG-RCHPVDGTCACEPG 263
Query: 472 WQRGNCSVPCPPGTWGFSCNASC-QCAHEAVCSPQTGAC-TCTPGWHGAHCQLPCPKGQF 529
++ C PCP G +G C C QC + C+ G C TC PGW+G C PC G +
Sbjct: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Query: 530 GEGCASRCD-CDHSDGCDPVHGRC-QCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGT 587
GEGC+ RC C C+ V G+C +C AGW+G RC C G +G +C+ C G
Sbjct: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH 383
Query: 588 CLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCY 638
C ++G C+C+PG GP C +C PG +G C + C P G C+
Sbjct: 384 CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACH 434
Score = 248 bits (633), Expect = 2e-65
Identities = 137/423 (32%), Positives = 184/423 (43%), Gaps = 55/423 (13%)
Query: 77 RQVVKTDHRQRLQCCHGFYESRGFC-VPLCA--QECVHGR-CVAPNQCQCVPGWRGDDCS 132
R V + Q CC G+ + C + +C C CV P +C+C G+ G +C
Sbjct: 51 RNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCD 110
Query: 133 SECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQ 192
++C WGP C + CSC + C+ +G C+C + +G C+ CQ
Sbjct: 111 TKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARR-------------WGARCEHACQ 157
Query: 193 CHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ-GSCSCP 251
C C P++GAC C G C +C +C +T C PQ G+C C
Sbjct: 158 CQHGTCHPRSGACRCEPGWWGAQCASAC-------YCSATSRCD-------PQTGACLCH 203
Query: 252 PGWMGTICS----------------LPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAP 295
GW G C+ C E G C + C+C G C G C C P
Sbjct: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEP 262
Query: 296 GYTGDRCREECPVGRFGQDCAETC-DCAPDARCFPANGACL-CEHGFTGDRCTDRLCPDG 353
GY G CRE CP G +G C C C C A G CL CE G+ G +C D+ C G
Sbjct: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKC-DQPCATG 321
Query: 354 FYGLSCQAPCTCDREHSLSCHPMNGECS-CLPGWAGLHCNESCPQDTHGPGCQEHCLCLH 412
FYG C C R+ +C+ + G+C+ C GW G C C T+G C C
Sbjct: 322 FYGEGCSHRCPPCRDGH-ACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCG 380
Query: 413 GGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGW 472
G C SG C C+PG GPHC CPP +G +C+ CSC C P+ G C +
Sbjct: 381 SGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHED-TCDPVTGACHLETNQ 439
Query: 473 QRG 475
++G
Sbjct: 440 RKG 442
Score = 239 bits (610), Expect = 1e-62
Identities = 191/687 (27%), Positives = 254/687 (36%), Gaps = 126/687 (18%)
Query: 404 CQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPID 463
C+ + C VC G C+C GY G +C + CP +G +C CSC C +
Sbjct: 80 CEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVT 138
Query: 464 GECVCK-EGW----------QRGNC-----SVPCPPGTWGFSCNASCQCAHEAVCSPQTG 507
G+C C W Q G C + C PG WG C ++C C+ + C PQTG
Sbjct: 139 GQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTG 198
Query: 508 ACTCTPGWHGAHC----------------QLPCPKGQFGEGCASRCDCDHSDGCDPVHGR 551
AC C GW G C + C + FG C C C C PV G
Sbjct: 199 ACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGT 257
Query: 552 CQCQAGWMGARCHLSCPEGLWGVNCSNTC-TCKNGGTCLPENGNCV-CAPGFRGPSCQRS 609
C C+ G+ G C CP G +G+ C C CK C G C+ C PG+ G C +
Sbjct: 258 CACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP 317
Query: 610 CQPGRYGK----RCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTC 665
C G YG+ RC PC+ H+ H + C AGW G C C G +GE+CA C
Sbjct: 318 CATGFYGEGCSHRCPPCR-DGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVC 376
Query: 666 QCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVC 725
G C Q G C+C G G HC CP G GA+C+Q C C + C P TGAC
Sbjct: 377 ADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHE-DTCDPVTGAC-- 433
Query: 726 PPGHSGAPCRIGIQEPFTVMPTTPVAYNSLGAVIGIAVLGSLVVALVALFIGYRHWQKGK 785
+ N V+G L L+V L+ +G +GK
Sbjct: 434 -----------------------HLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGK 470
Query: 786 EHHHLAVAYS--------SGRLDGSEYVMPDVPPSYSHYYSNPSYH-----TLSQCSPNP 832
+ ++ GR +P +P H TL+ P
Sbjct: 471 DPTRRELSLGRKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEP 530
Query: 833 PPPNKVPGPLFASLQN---------------PERPGGAQGHDNHT-TLPADWKHRREPPP 876
P + P P ++S + P A+ D T+PA+ P P
Sbjct: 531 PSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAE---APAPSP 587
Query: 877 GPLDRGSS---------RLDRSYSYSYSNGPGPFYNKGLISEEELGA----SVASLSSEN 923
PL +S D S S GPG + E A + LS
Sbjct: 588 VPLTTPASAEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSP 647
Query: 924 PYATIRDLPSLPGGPRESSYMEMK-------GPPSGSPPRQPPQFWDSQRRRQPQPQRDS 976
+ P P + S++ K PS PP S+R+R P + +
Sbjct: 648 SPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPS-DKSA 706
Query: 977 GTYEQPSPLIHDRDSVGSQPPLPPGLP 1003
T E SP D P PPGLP
Sbjct: 707 HTVEHGSPRTRD------PTPRPPGLP 727
Score = 238 bits (608), Expect = 2e-62
Identities = 203/757 (26%), Positives = 285/757 (37%), Gaps = 105/757 (13%)
Query: 359 CQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQA 418
C+ TC E+ + P GEC C G+ G +C+ CP+ GP C+E C C G C+
Sbjct: 80 CEGNSTCS-ENEVCVRP--GECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCED 136
Query: 419 TSGLCQCAPGYTGPHC----------------ASLCPPDTYGVNCSARCSCENAIACSPI 462
+G C C G C A C P +G C++ C C C P
Sbjct: 137 VTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQ 196
Query: 463 DGECVCKEGW------------------QRGNCSVPCPPGTWGFSCNASCQCAHEAVCSP 504
G C+C GW Q G C C T+G C+ CQC C P
Sbjct: 197 TGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQ--CRERTFGARCDRYCQC-FRGRCHP 253
Query: 505 QTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC-DCDHSDGCDPVHGRC-QCQAGWMGAR 562
G C C PG+ G +C+ PCP G +G GC RC C C GRC C+ GW G +
Sbjct: 254 VDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTK 313
Query: 563 CHLSCPEGLWGVNCSNTCT-CKNGGTCLPENGNCV-CAPGFRGPSCQRSCQPGRYGKRCV 620
C C G +G CS+ C C++G C G C C G+ G C+ C G YG+ C
Sbjct: 314 CDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCA 373
Query: 621 -PCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHG------GTC 673
C C +G C C G GP C+ CPPG G +CAQ C CH G C
Sbjct: 374 FVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGAC 433
Query: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPET--GACVCPPGHSG 731
H + +G L C L + C C C + E G P G
Sbjct: 434 HLETNQRKGVMGAGALLVLLVCLLLSLLGCC---CACRGKDPTRRELSLGRKKAPHRLCG 490
Query: 732 APCRIGIQEPFTVM-----PTTPVAYNSLGAVIGIAVLG--------SLVVALVALFIGY 778
RI ++ P + P VA++ L + + L S + A F +
Sbjct: 491 RFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSF 550
Query: 779 RHWQKGKEHHHLAVAYSSGRLDGSEYVMPDVPPSYSHYYSNPSYHTLSQCSPNPPPPNK- 837
+G + V + + + +P VP P S P P +
Sbjct: 551 DTTDEGPVY---CVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSD 607
Query: 838 -------VPGP---LFASLQNPE-RPGGAQGHDNHTTLPADWKHRREPPPGPLDRGS-SR 885
V GP L+A + E RP A+G +L + R+ PPP P + S
Sbjct: 608 SERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSW 667
Query: 886 LDRSYSYSYSN---GPGPFYNKGLISEEELGASVASLSS---ENPYATIRD-LPSLPGGP 938
+ +S + + P P ++ S + + + S+ E+ RD P PG P
Sbjct: 668 IHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLP 727
Query: 939 RESSYMEMKGPPSGSPPRQPPQFWDSQRRRQPQPQRDSGTY------EQPSPLIHDRDSV 992
E++ + PP P RRR P + ++ + + L ++
Sbjct: 728 EEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSLGRAEVAL 787
Query: 993 GSQPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPS 1029
G+Q P PP K S P P R PP+
Sbjct: 788 GAQGPREKPAPP---QKAKRSVPPA----SPARAPPA 817
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 11/110 (10%)
Query: 632 PSNGTCYCLAGWT--GPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGH 689
P + C AGW G +C C C C + G C C G+ G
Sbjct: 57 PGSQVPTCCAGWRQQGDECGIAV--------CEGNSTCSENEVC-VRPGECRCRHGYFGA 107
Query: 690 HCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQ 739
+C CP +G +C + C C P +C TG C C GA C Q
Sbjct: 108 NCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ 157
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 255 bits (651), Expect = 2e-67
Identities = 225/750 (30%), Positives = 283/750 (37%), Gaps = 232/750 (30%)
Query: 55 CERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRC 114
CE W GP TC PT ++ + C +G CV GRC
Sbjct: 158 CEPGWGGP-TCSDPTDA------EIPPSSPPSASGSCPDDCNDQG--------RCVRGRC 202
Query: 115 VAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNC 174
V C PG+ G C W P C P C C GVC C +G P+C
Sbjct: 203 V------CFPGYTGPSCG-------W-PSC--PGDCQGRGRC--VQGVCVCRAGFSGPDC 244
Query: 175 LQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDV-SCSQGTSGFFCPSTH 233
Q P C R +C G G C C TG C + SC +G C
Sbjct: 245 SQRSCPR----GCSQRGRCEG-------GRCVCDPGYTGDDCGMRSCPRG-----CSQRG 288
Query: 234 SCQNGGVFQTPQGSCSCPPGWMGTICSL-PCPEGFHGPNCSQECRCHNGGLCDRFTGQCR 292
C+NG C C PG+ G C + CP G CSQ RC +G +C
Sbjct: 289 RCENG--------RCVCNPGYTGEDCGVRSCPRG-----CSQRGRCKDG--------RCV 327
Query: 293 CAPGYTGDRC------------------REECPVGRFGQDCA-ETC--DCAPDARCFPAN 331
C PGYTG+ C R C G G+DC+ TC DC RC +
Sbjct: 328 CDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC--ED 385
Query: 332 GACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHC 391
G C+C+ G++GD C R CP C C+ +G C C PG+ G C
Sbjct: 386 GECICDTGYSGDDCGVRSCPG-----DCNQRGRCE----------DGRCVCWPGYTGTDC 430
Query: 392 -NESCPQDTHGPGCQEH--CLCLHG------------GVCQAT----SGLCQCAPGYTGP 432
+ +CP+D G G E+ C+C G G C+ SG C C PGYTG
Sbjct: 431 GSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGR 490
Query: 433 HCAS-LCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCN 491
C + CP D C R C +DG CVC G+ +C PG
Sbjct: 491 DCGTRACPGD-----CRGRGRC--------VDGRCVCNPGFTGEDCGSRRCPG------- 530
Query: 492 ASCQCAHEAVCSPQTGACTCTPGWHGAHCQL-PCPKGQFGEGCASRCDCDHSDGCDPVHG 550
C +C + G C C G+ G C CP G C R C + G
Sbjct: 531 ---DCRGHGLC--EDGVCVCDAGYSGEDCSTRSCPGG-----CRGRGQC--------LDG 572
Query: 551 RCQCQAGWMGARCHL-SCP-----------------EGLWGVNCS-NTC--TCKNGGTCL 589
RC C+ G+ G C + CP EG +CS TC C G C
Sbjct: 573 RCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC- 631
Query: 590 PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCS 649
E G C+C PG+ GP+C R P C C G C C G+ G DC
Sbjct: 632 -EEGRCLCDPGYTGPTC---------ATRMCPADCRGRGRC--VQGVCLCHVGYGGEDCG 679
Query: 650 QPCPPGHWGENCAQTCQCHHGGTCHPQD----GSCICPLGWTGHHC-LEGCPLGTFGANC 704
Q PP A C G C P++ G C+C G+ G C ++ CP +C
Sbjct: 680 QEEPP-------ASACP----GGCGPRELCRAGQCVCVEGFRGPDCAIQTCP-----GDC 723
Query: 705 SQPCQCGPGEKCHPETGACVCPPGHSGAPC 734
G GE CH G+CVC G++G C
Sbjct: 724 R-----GRGE-CHD--GSCVCKDGYAGEDC 745
Score = 238 bits (606), Expect = 3e-62
Identities = 203/681 (29%), Positives = 249/681 (36%), Gaps = 217/681 (31%)
Query: 158 PKSGVCSCPSGLQPP-------------------------NCLQPCTP-----GYYGPAC 187
P S C CP G +PP C C P G
Sbjct: 80 PPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDV 139
Query: 188 QFRCQCHGAPCDPQTGACFCPAERTGPSCD-------VSCSQGTSGFFCPSTHSCQNGGV 240
+ C HG D C C GP+C S ++ CP C + G
Sbjct: 140 RTLCSLHGV-FDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPD--DCNDQG- 195
Query: 241 FQTPQGSCSCPPGWMGTICSLP------------------CPEGFHGPNCSQEC---RCH 279
+ +G C C PG+ G C P C GF GP+CSQ C
Sbjct: 196 -RCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCS 254
Query: 280 NGGLCDRFTGQCRCAPGYTGDRC-REECPVGRFGQDCAETCDCAPDARCFPANGACLCEH 338
G C+ G+C C PGYTGD C CP G C+ RC NG C+C
Sbjct: 255 QRGRCE--GGRCVCDPGYTGDDCGMRSCPRG-----------CSQRGRC--ENGRCVCNP 299
Query: 339 GFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHC-NESCPQ 397
G+TG+ C R CP G C C +G C C PG+ G C SCP
Sbjct: 300 GYTGEDCGVRSCPRG-----CSQRGRC----------KDGRCVCDPGYTGEDCGTRSCPW 344
Query: 398 DTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCAS-LCPPDTYGVNCSARCSCENA 456
D C GG C G C C PGYTG C++ CP D C R CE
Sbjct: 345 D-----------CGEGGRC--VDGRCVCWPGYTGEDCSTRTCPRD-----CRGRGRCE-- 384
Query: 457 IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWH 516
DGEC+C G+ +C V PG CN +C + G C C PG+
Sbjct: 385 ------DGECICDTGYSGDDCGVRSCPG----DCNQRGRC--------EDGRCVCWPGYT 426
Query: 517 GAHC-QLPCPK-----------------GQFGEGCASRC---DCDHSDGCDPVHGRCQCQ 555
G C CP+ G GE C R DC C+ GRC C
Sbjct: 427 GTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCE--SGRCMCW 484
Query: 556 AGWMGARCHL-SCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGR 614
G+ G C +CP C+ G C+ +G CVC PGF G C
Sbjct: 485 PGYTGRDCGTRACPG-----------DCRGRGRCV--DGRCVCNPGFTGEDC-------- 523
Query: 615 YGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQ------------------PCPPGH 656
G R P C H C +G C C AG++G DCS C G+
Sbjct: 524 -GSRRCPGDCRGHGLC--EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGY 580
Query: 657 WGENC-AQTC--QCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPG 713
GE+C + C C G C QDG CIC W G + E C + T +NC +C
Sbjct: 581 SGEDCGVRQCPNDCSQHGVC--QDGVCIC---WEG-YVSEDCSIRTCPSNCHGRGRC--- 631
Query: 714 EKCHPETGACVCPPGHSGAPC 734
E G C+C PG++G C
Sbjct: 632 -----EEGRCLCDPGYTGPTC 647
Score = 234 bits (596), Expect = 4e-61
Identities = 221/719 (30%), Positives = 267/719 (37%), Gaps = 185/719 (25%)
Query: 44 SRPFSLLPSEPCERPWEGPHTC------PQPTVVYRTVY---RQVVKTDHRQRLQCCHGF 94
SR LP+ P P G HT P + TV +QVV T HR L G
Sbjct: 28 SRSNVTLPA-PRPPPQPGGHTVGAGVGSPSSQLYEHTVEGGEKQVVFT-HRINLPPSTGC 85
Query: 95 YESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGP---QCDKPCSCG 151
G P+ A E R + V G + + C+ C P Q D C
Sbjct: 86 GCPPGTEPPVLASEVQALRVRLEILEELVKGLK-EQCTGGCCPASAQAGTGQTDVRTLCS 144
Query: 152 NNSSCDPKSGVCSCPSGLQPPNC-------LQPCTPGYYGPACQFRCQCHGAPCDPQTGA 204
+ D CSC G P C + P +P +C C G G
Sbjct: 145 LHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCV---RGR 201
Query: 205 CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSL-PC 263
C C TGPSC CP CQ G + QG C C G+ G CS C
Sbjct: 202 CVCFPGYTGPSCGWPS--------CPG--DCQGRG--RCVQGVCVCRAGFSGPDCSQRSC 249
Query: 264 PEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRC-REECPVGRFGQDCAETCDCA 322
P G CSQ RC G +C C PGYTGD C CP G C+
Sbjct: 250 PRG-----CSQRGRCEGG--------RCVCDPGYTGDDCGMRSCPRG-----------CS 285
Query: 323 PDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSC 382
RC NG C+C G+TG+ C R CP G C C +G C C
Sbjct: 286 QRGRC--ENGRCVCNPGYTGEDCGVRSCPRG-----CSQRGRCK----------DGRCVC 328
Query: 383 LPGWAGLHCN-ESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCAS-LCPP 440
PG+ G C SCP D C GG C G C C PGYTG C++ CP
Sbjct: 329 DPGYTGEDCGTRSCPWD-----------CGEGGRC--VDGRCVCWPGYTGEDCSTRTCPR 375
Query: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEA 500
D C R CE DGEC+C G+ +C V PG CN +C
Sbjct: 376 D-----CRGRGRCE--------DGECICDTGYSGDDCGVRSCPG----DCNQRGRC---- 414
Query: 501 VCSPQTGACTCTPGWHGAHC-QLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWM 559
+ G C C PG+ G C CP+ G G RC+ +G C C AG+
Sbjct: 415 ----EDGRCVCWPGYTGTDCGSRACPRDCRGRG---RCE----------NGVCVCNAGYS 457
Query: 560 GARCHL-SCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKR 618
G C + SCP C+ G C E+G C+C PG+ G C G R
Sbjct: 458 GEDCGVRSCPGD-----------CRGRGRC--ESGRCMCWPGYTGRDC---------GTR 495
Query: 619 CVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDG 678
P C C +G C C G+TG DC PG C G C +DG
Sbjct: 496 ACPGDCRGRGRC--VDGRCVCNPGFTGEDCGSRRCPG----------DCRGHGLC--EDG 541
Query: 679 SCICPLGWTGHHC-LEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRI 736
C+C G++G C CP G G QC G CVC G+SG C +
Sbjct: 542 VCVCDAGYSGEDCSTRSCPGGCRGRG-----QCLDGR--------CVCEDGYSGEDCGV 587
Score = 140 bits (353), Expect = 6e-33
Identities = 128/453 (28%), Positives = 163/453 (35%), Gaps = 119/453 (26%)
Query: 105 CAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMW---GPQCDKPCSCGNNSSCDPKSG 161
C +C G +C C PG+ G+DCS+ P G D C C S D G
Sbjct: 342 CPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD-CG 400
Query: 162 VCSCPSGLQPPNCLQP----CTPGYYGPACQFRC---QCHG-APCDPQTGACFCPAERTG 213
V SCP + C PGY G C R C G C+ G C C A +G
Sbjct: 401 VRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCE--NGVCVCNAGYSG 458
Query: 214 PSCDVS------------------CSQGTSGFFCPSTHSCQNG--GVFQTPQGSCSCPPG 253
C V C G +G C T +C G + G C C PG
Sbjct: 459 EDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDC-GTRACPGDCRGRGRCVDGRCVCNPG 517
Query: 254 WMGTICS------------------LPCPEGFHGPNCS-QECR--CHNGGLCDRFTGQCR 292
+ G C C G+ G +CS + C C G C G+C
Sbjct: 518 FTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQC--LDGRCV 575
Query: 293 CAPGYTGDRCR-EECP-----------------VGRFGQDCA-ETC--DCAPDARCFPAN 331
C GY+G+ C +CP G +DC+ TC +C RC
Sbjct: 576 CEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC--EE 633
Query: 332 GACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHC 391
G CLC+ G+TG C R+CP C+ C + G C C G+ G C
Sbjct: 634 GRCLCDPGYTGPTCATRMCP-----ADCRGRGRC----------VQGVCLCHVGYGGEDC 678
Query: 392 NESCPQDTHGP-GCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCA-SLCPPDTYGVNCSA 449
+ P + P GC LC +G C C G+ GP CA CP D C
Sbjct: 679 GQEEPPASACPGGCGPRELC--------RAGQCVCVEGFRGPDCAIQTCPGD-----CRG 725
Query: 450 RCSCENAIACSPIDGECVCKEGWQRGNCSVPCP 482
R C DG CVCK+G+ +C P
Sbjct: 726 RGECH--------DGSCVCKDGYAGEDCGEEVP 750
Score = 119 bits (299), Expect = 1e-26
Identities = 105/374 (28%), Positives = 133/374 (35%), Gaps = 100/374 (26%)
Query: 91 CHGFYESRGFCVPLCAQECV-HGRCVAPNQCQCVPGWRGDDCSSE--------------- 134
C+ Y V C +C GRC + +C C PG+ G DC +
Sbjct: 452 CNAGYSGEDCGVRSCPGDCRGRGRCES-GRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 510
Query: 135 ---CAPGMWGPQCDK---PCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQ 188
C PG G C P C + C+ GVC C +G +C PG C+
Sbjct: 511 RCVCNPGFTGEDCGSRRCPGDCRGHGLCE--DGVCVCDAGYSGEDCSTRSCPG----GCR 564
Query: 189 FRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSC 248
R QC G C C +G C V CP + C GV Q G C
Sbjct: 565 GRGQC-------LDGRCVCEDGYSGEDCGVR--------QCP--NDCSQHGVCQ--DGVC 605
Query: 249 SCPPGWMGTICSL-PCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREE-C 306
C G++ CS+ CP CH G C+ G+C C PGYTG C C
Sbjct: 606 ICWEGYVSEDCSIRTCPS-----------NCHGRGRCEE--GRCLCDPGYTGPTCATRMC 652
Query: 307 PVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCD 366
P DC RC G CLC G+ G+ C P +C C
Sbjct: 653 P-----------ADCRGRGRC--VQGVCLCHVGYGGEDCGQEEPP----ASACPGGCG-P 694
Query: 367 REHSLSCHPMNGECSCLPGWAGLHCN-ESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQC 425
RE + G+C C+ G+ G C ++CP D G G + G C C
Sbjct: 695 RELCRA-----GQCVCVEGFRGPDCAIQTCPGDCRGRG-------------ECHDGSCVC 736
Query: 426 APGYTGPHCASLCP 439
GY G C P
Sbjct: 737 KDGYAGEDCGEEVP 750
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 250 bits (639), Expect = 4e-66
Identities = 233/792 (29%), Positives = 284/792 (35%), Gaps = 227/792 (28%)
Query: 103 PLCAQECVHG-RC-VAPNQ---CQCVPGWRGDDCSS---ECAPGMWGPQCDKPCSCGNNS 154
P + C HG RC V P+ C C PG++G C S EC G +PC G
Sbjct: 122 PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG-------EPCRHGGTC 174
Query: 155 SCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGP 214
P S C CP+G P C P P P C+ C + T C C G
Sbjct: 175 LNTPGSFRCQCPAGYTGPLCENPAVPCAPSP-CRNGGTCRQS--GDLTYDCACLPGFEGQ 231
Query: 215 SCDVSCSQGTSGFFCPSTHSCQNGG--VFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNC 272
+C+V+ CP H C NGG V +C CPP W G C+ E PN
Sbjct: 232 NCEVNVDD------CPG-HRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNA 284
Query: 273 SQECRCHNGGLCDRFTG--QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFP- 329
CHNGG C G C C G+TG+ C + DCA T C A C
Sbjct: 285 -----CHNGGTCFNTLGGHSCVCVNGWTGESCSQNI------DDCA-TAVCFHGATCHDR 332
Query: 330 -ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGE--CSCLPGW 386
A+ C C G TG C D C CD +P+NG C+C PG+
Sbjct: 333 VASFYCACPMGKTGLLCH---LDDACVSNPCHEDAICD------TNPVNGRAICTCPPGF 383
Query: 387 AGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG--LCQCAPGYTGPHCASLCPPDTYG 444
G C++ + + G C H G C T G LCQC GYTGP C +
Sbjct: 384 TGGACDQDVDECSIGAN-----PCEHLGRCVNTQGSFLCQCGRGYTGPRCET-------D 431
Query: 445 VNCSARCSCENAIACSPIDGE--CVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVC 502
VN C N C G+ C+C G+ C V C +S C + VC
Sbjct: 432 VNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDID------ECQSS-PCVNGGVC 484
Query: 503 SPQTG--ACTCTPGWHGAHCQL--------PCPKG----QFGEGCASRCD-------CDH 541
+ +CTC G+ G+ CQL PC G +G RC CD
Sbjct: 485 KDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDR 544
Query: 542 S-DGCDP---VHGR---------CQCQAGWMGARCH------------------------ 564
+ D C P HGR C C G+ G RC
Sbjct: 545 NVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKY 604
Query: 565 -LSCPEGLWGVNC--------SNTCT---CKNGGTCLPENGNCVCAPGFRGPSCQ----- 607
CP G GVNC SN CT C++G +CVC PGF GP C
Sbjct: 605 LCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDG----INRYDCVCQPGFTGPLCNVEINE 660
Query: 608 ---------RSCQPGRYGKRCV---------------PC--KCANHSFCH--PSNGTCYC 639
SC G G RC+ PC + +H C+ P C C
Sbjct: 661 CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVC 720
Query: 640 LAGWTGPDCSQ---------------------------PCPPGHWGENC--AQTC---QC 667
GW+GP CSQ CPPG G C C C
Sbjct: 721 EPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPC 780
Query: 668 HHGGTCHPQDGS---CICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETG--A 722
HGG C G C CP GW G C + C+ P CGP C G +
Sbjct: 781 EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVD------ECAGPAPCGPHGICTNLAGSFS 834
Query: 723 CVCPPGHSGAPC 734
C C G++G C
Sbjct: 835 CTCHGGYTGPSC 846
Score = 241 bits (615), Expect = 3e-63
Identities = 211/701 (30%), Positives = 256/701 (36%), Gaps = 144/701 (20%)
Query: 105 CAQE-CVHGRCV-APN--QCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKS 160
CA E C HG C AP +C C PGW G CS A Q PC G S D
Sbjct: 699 CAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQ---PCRAGGTCSSDGMG 755
Query: 161 GVCSCPSGLQPPNC--LQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDV 218
C+CP G+Q C L PCTP C+ +C AP Q C CP GP C
Sbjct: 756 FHCTCPPGVQGRQCELLSPCTPN----PCEHGGRCESAP--GQLPVCSCPQGWQGPRCQQ 809
Query: 219 SCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECR- 277
+ C C G+ GS SC C G+ GP+C Q+
Sbjct: 810 DVDE------CAGPAPCGPHGICTNLAGSFSCT-----------CHGGYTGPSCDQDIND 852
Query: 278 -----CHNGGLCDRFTGQ--CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARC-FP 329
C NGG C G C C PG+ G RC + +C C P
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDV------DECLSN-PCGPGTCTDHV 905
Query: 330 ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC-DREHSLSCHPMNGECSCLPGWAG 388
A+ C C G+ G C L PD SC TC D +S SC C PG+ G
Sbjct: 906 ASFTCTCPPGYGGFHCEQDL-PDCSPS-SCFNGGTCVDGVNSFSC-------LCRPGYTG 956
Query: 389 LHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG--LCQCAPGYTGPHCASLCPPDTYGVN 446
HC P CLHGGVC A C C +TGP C +L V+
Sbjct: 957 AHCQHEADPCLSRP-------CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-------VD 1002
Query: 447 CSARCSCENAIACSPIDGECVCKEGWQRGNC---SVPCPPGTW--GFSCNASCQCAHEAV 501
+R C+N C C+C GW C S+PC G CQ + V
Sbjct: 1003 WCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCV 1062
Query: 502 CSPQTGACTCTPGWHGAHCQL--------PCPKGQFGEGCAS--RCDC---DHSDGCDPV 548
+ C C G G+HC+ PC G G C+C + D C+
Sbjct: 1063 DEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDD 1122
Query: 549 HGRCQ---CQAGW----MGARCHLSCPEGLWGVNCS---NTC----------TCKNGGTC 588
C CQ G + AR SCP G GV C + C C + GTC
Sbjct: 1123 VDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTC 1182
Query: 589 LPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HPSNG-TCYCLAGW 643
+ G C C PG+ G C+ R G C A+ C P G C C AG+
Sbjct: 1183 VDLVGGFRCTCPPGYTGLRCEADINECRSGA----CHAAHTRDCLQDPGGGFRCLCHAGF 1238
Query: 644 TGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDG-------SCICPLGWTGHHCLEGCP 696
+GP C P ++ C HGG C P G +C C + G C
Sbjct: 1239 SGPRCQTVLSP-------CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERV-- 1289
Query: 697 LGTFGANCSQPCQCGPGEKCH--PETGACVCPPGHSGAPCR 735
A + QC G C P C CPPG SG CR
Sbjct: 1290 -----ARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR 1325
Score = 216 bits (551), Expect = 7e-56
Identities = 217/781 (27%), Positives = 277/781 (35%), Gaps = 197/781 (25%)
Query: 90 CCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCS 149
C GF G L EC C N +CV G +C CA G G CD+
Sbjct: 495 CPSGF---SGSTCQLDVDECASTPC--RNGAKCVDQPDGYEC--RCAEGFEGTLCDR--- 544
Query: 150 CGNNSSCDPKSGVCS---CPSGLQPPNCLQPCTPGYYGPACQFRC-QCHGAPCDP----- 200
N C P C C G+ +C C PGY G C+ + +C PC
Sbjct: 545 --NVDDCSPDP--CHHGRCVDGIASFSCA--CAPGYTGTRCESQVDECRSQPCRHGGKCL 598
Query: 201 ---QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGT 257
C CP+ TG +C+V+ S P T G+ + C C PG+ G
Sbjct: 599 DLVDKYLCRCPSGTTGVNCEVNIDDCASN---PCTFGVCRDGINRY---DCVCQPGFTGP 652
Query: 258 ICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDC-- 315
+C++ E P C GG C G G RC CP G C
Sbjct: 653 LCNVEINECASSP-------CGEGG---------SCVDGENGFRCL--CPPGSLPPLCLP 694
Query: 316 -AETCDCAPDAR--CFPANGA--CLCEHGFTGDRCTDRL--------------------- 349
+ C P + C+ A G C+CE G++G RC+ L
Sbjct: 695 PSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGM 754
Query: 350 -----CPDGFYGLSCQ--APCTCDR-EHSLSCHPMNGE---CSCLPGWAGLHCNESCPQD 398
CP G G C+ +PCT + EH C G+ CSC GW G C + +
Sbjct: 755 GFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDEC 814
Query: 399 THGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHC---ASLCPPD--TYGVNC-----S 448
C H +C + A S C C GYTGP C + C P+ G +C S
Sbjct: 815 AGPAPCGPHGICTN----LAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGS 870
Query: 449 ARCSCENAIA---CSPIDGECV--------CKEGWQRGNCSVPCPPGTWGFSCN------ 491
CSC A C+ EC+ C + C+ CPPG GF C
Sbjct: 871 FSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCT--CPPGYGGFHCEQDLPDC 928
Query: 492 --ASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVH 549
+SC V + +C C PG+ GAHCQ + C SR C H C H
Sbjct: 929 SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ------HEADPCLSR-PCLHGGVCSAAH 981
Query: 550 G--RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQ 607
RC C + G +C V+ + C+NGG C+ C+C PG+ G C
Sbjct: 982 PGFRCTCLESFTGPQCQTL-------VDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCD 1034
Query: 608 RSCQPGRYGKRCVP------CKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENC 661
P R + C+ S+ C C G TG C Q P
Sbjct: 1035 IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDP-----CL 1089
Query: 662 AQTCQCHHGGTCHPQDGS--CICPLGWTGHHC-------------------------LEG 694
AQ CQ HGGTC G C C G+ G +C L
Sbjct: 1090 AQPCQ--HGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCS 1147
Query: 695 CPLGTFGANCS-QPCQCGPGE------------KCHPETGA--CVCPPGHSGAPCRIGIQ 739
CP GT G C CGPG C G C CPPG++G C I
Sbjct: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADIN 1207
Query: 740 E 740
E
Sbjct: 1208 E 1208
Score = 187 bits (475), Expect = 4e-47
Identities = 195/681 (28%), Positives = 231/681 (33%), Gaps = 179/681 (26%)
Query: 99 GFCVPLCAQ---ECVHGRC--------VAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKP 147
GF P CA+ EC+ C VA C C PG+ G C + P C P
Sbjct: 878 GFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDL------PDCS-P 930
Query: 148 CSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQ-------CHGAPCDP 200
SC N +C G+ +CL C PGY G CQ HG C
Sbjct: 931 SSCFNGGTC---------VDGVNSFSCL--CRPGYTGAHCQHEADPCLSRPCLHGGVCSA 979
Query: 201 QTGA--CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTI 258
C C TGP C +C S CQNGG C CPPGW G +
Sbjct: 980 AHPGFRCTCLESFTGPQCQTLVD------WC-SRQPCQNGGRCVQTGAYCLCPPGWSGRL 1032
Query: 259 C---SLP--------------------------------CPEGFHGPNCSQEC------R 277
C SLP CPEG G +C QE
Sbjct: 1033 CDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQP 1092
Query: 278 CHNGGLCDRFTG--QCRCAPGYTGDRCREE-------------------------CPVGR 310
C +GG C + G C C PGY GD C ++ CP G
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1152
Query: 311 FGQDC-AETCDCAP------DARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPC 363
G C DC P RC NG C+ G G RCT CP G+ GL C+A
Sbjct: 1153 LGVLCEINEDDCGPGPPLDSGPRCL-HNGTCVDLVG--GFRCT---CPPGYTGLRCEADI 1206
Query: 364 TCDREHSLSCHPMN-GECSCLPGWAGLHCNESCPQDTHGPGCQ------EHCLCLHGGVC 416
R S +CH + +C PG G C C GP CQ E C HGG C
Sbjct: 1207 NECR--SGACHAAHTRDCLQDPG-GGFRC--LCHAGFSGPRCQTVLSPCESQPCQHGGQC 1261
Query: 417 QATSG-------LCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCK 469
+ + G C CA + GP C + + C C+ +P C C
Sbjct: 1262 RPSPGPGGGLTFTCHCAQPFWGPRCERVA-RSCRELQCPVGVPCQQ----TPRGPRCACP 1316
Query: 470 EGWQRGNC-SVP-CPPGTWGFSCNASCQCAHEAVCSPQTGA----CTCTPGWHGAHCQLP 523
G +C S P PPG SC A+ C H C P A C C GW G C+ P
Sbjct: 1317 PGLSGPSCRSFPGSPPGASNASC-AAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAP 1375
Query: 524 CPKGQFG-EGCASRCDCDHSDGCDPVHGRCQCQ-AGWMGARCHLSCPEGLWGVNCSNTCT 581
+ E R C G C GW G C LS + W C
Sbjct: 1376 AAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDP-W-----RQCE 1429
Query: 582 CKNGGTCLPENGNCVCAPGFRGPSC---QRSCQPGRYGKRCVPC---KCANH---SFCHP 632
C N C P P+C C G + C P CA+H C
Sbjct: 1430 ALQ---CWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQ 1486
Query: 633 SNGTCYCLAGWTGPDCSQPCP 653
T C GW G DC+ P
Sbjct: 1487 GCNTEEC--GWDGLDCASEVP 1505
Score = 72.8 bits (177), Expect = 2e-12
Identities = 57/183 (31%), Positives = 69/183 (37%), Gaps = 30/183 (16%)
Query: 576 CSNTCTCKNGGTC--LPEN-GNCVCAPGFRGPSCQRS--CQPGRYGKRCVPCKCANHSFC 630
C + C NGG C LP C+C PG+ G CQ C G R V C +
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGV---CQSSVVA 99
Query: 631 HPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHP-QDGSCICPLGWTGH 689
+ +C C G+ GPDCS P P + C HG C DG +C
Sbjct: 100 GTARFSCRCPRGFRGPDCSLPDP--------CLSSPCAHGARCSVGPDGRFLC------- 144
Query: 690 HCLEGCPLGTFGANC-SQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTT 748
CP G G +C S +C GE C G C+ PG C G P P
Sbjct: 145 ----SCPPGYQGRSCRSDVDECRVGEPCR-HGGTCLNTPGSFRCQCPAGYTGPLCENPAV 199
Query: 749 PVA 751
P A
Sbjct: 200 PCA 202
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 246 bits (629), Expect = 6e-65
Identities = 256/943 (27%), Positives = 314/943 (33%), Gaps = 300/943 (31%)
Query: 53 EPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFY----ESRGFCVPLCAQE 108
E C+ E P CP R R ++ R + C G+ + R FC A
Sbjct: 112 ERCQAKLEDP--CPPSFCSKRG--RCHIQASGRPQCSCMPGWTGEQCQLRDFC---SANP 164
Query: 109 CVHGR-CVAPN---QCQCVPGWRGDDCSSECAPGMWGP-QCDKPCSCGNNSSCDPKSGVC 163
CV+G C+A QC C PG+ G C + P C K SC N S C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLG----SFQC 220
Query: 164 SCPSGLQPPNC-------------------LQP----------CTPGYYGPACQFR---C 191
CP G + P C L P C PG+ GP C+ C
Sbjct: 221 LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
Query: 192 QCH----GAPCDP--QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ 245
H G C T C CP TG CS+ C+NGG Q
Sbjct: 281 VSHQCQNGGTCQDGLDTYTCLCPETWTG----WDCSEDVDECETQGPPHCRNGGTCQNSA 336
Query: 246 GS--CSCPPGWMGTIC-------------------------SLPCPEGFHGPNCSQECRC 278
GS C C GW GT C S CP G G C E C
Sbjct: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMC 396
Query: 279 -----HNGGLCDR--FTGQ--CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFP 329
H C TG C C PGY+G C ++ Q C+ P
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTP 456
Query: 330 ANGACLCEHGFTGDRCTDR------------------------LCPDGFYGLSCQ----- 360
+ CLC G+TG RC LCP G G C+
Sbjct: 457 GSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNE 516
Query: 361 ---APCTCDREHSLSCHPM-NG-ECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGV 415
APC + CH + NG +C CLPG++G C E + P C +GG
Sbjct: 517 CASAPCL----NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP-------CANGGQ 565
Query: 416 CQATSGL--CQCAPGYTGPHCAS-------------------------LCPPDTYGVNCS 448
CQ G C+C PG+ GP C + LCP G C
Sbjct: 566 CQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCE 625
Query: 449 ---------------------ARCSC-ENAIACSPIDGECVCKEGW-QRGNCSVPCPPGT 485
A C C + + C+P + C C G QR +C C G
Sbjct: 626 VPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCV--CDVGW 683
Query: 486 WGFSCNA------SCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDC 539
G C A S CAH C PQ CT CP G G C+
Sbjct: 684 TGPECEAELGGCISAPCAHGGTCYPQPSGYNCT-----------CPTGYTGPTCSEEMTA 732
Query: 540 DHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNT------CTCKNGGTCLPENG 593
HS C G C G G C +CP G C + C NGGTC+ G
Sbjct: 733 CHSGPCLN-GGSCNPSPG--GYYC--TCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG 787
Query: 594 --NCVCAPGFRGPSCQ---------------RSCQPGRYGKRCV---------------- 620
+C+CA GF+GP C+ +CQ G RC+
Sbjct: 788 TFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDL 847
Query: 621 ----PCKCANHSFCHPSNGTCYCLAGWTGPDCSQP---CPPGHWGENCAQTCQCHHGGTC 673
PC +H + C CL GWTGP C+ P C + + CH+GG C
Sbjct: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC 907
Query: 674 HPQDGS--CICPLGWTGHHC------LEGCPLGTFGANC-SQP----CQCGPG------- 713
S C CP G+ G C E P GA C +QP CQC PG
Sbjct: 908 VDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQN-GATCMAQPSGYLCQCAPGYDGQNCS 966
Query: 714 --------EKCH------PETGA--CVCPPGHSGAPCRIGIQE 740
+ CH P+ G C CPPG G C + E
Sbjct: 967 KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDE 1009
Score = 241 bits (615), Expect = 3e-63
Identities = 218/774 (28%), Positives = 265/774 (34%), Gaps = 222/774 (28%)
Query: 120 CQCVPGWRG-------DDC------------------SSECAPGMWGPQC-------DKP 147
C CV GW G DDC S C PG G C +P
Sbjct: 341 CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400
Query: 148 CSCGNNSSCDPKSG--VCSCPSGLQPPNC---LQPCTPGYYGPACQFRCQCHGAPC--DP 200
C S +P +G +C C G P C L C GP+ C+ HG C P
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPS---PCE-HGGSCLNTP 456
Query: 201 QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICS 260
+ C CP TG C+ ++ S P + F C CPPG G +C
Sbjct: 457 GSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH-----CLCPPGLEGQLCE 511
Query: 261 LP-------------------------CPEGFHGPNCSQ---ECR---CHNGGLCDRFTG 289
+ C GF G C + ECR C NGG C G
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 290 --QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA--CLCEHGFTGDRC 345
C+C PG+ G RC+ E +C C A C GA CLC GFTG C
Sbjct: 572 AFHCKCLPGFEGPRCQTEV------DECLSD-PCPVGASCLDLPGAFFCLCPSGFTGQLC 624
Query: 346 ----------------------TDRLCPDGFYGLSCQAP---CTCDREHSLSCHPMNGEC 380
+ LCPDG G C P CTC H C
Sbjct: 625 EVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHGHC-----QRSSC 677
Query: 381 SCLPGWAGLHC-------------------------NESCPQDTHGPGCQEHCL------ 409
C GW G C N +CP GP C E
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 410 CLHGGVCQATSG--LCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG--E 465
CL+GG C + G C C P +TGP C + + C N C G
Sbjct: 738 CLNGGSCNPSPGGYYCTCPPSHTGPQCQT-------STDYCVSAPCFNGGTCVNRPGTFS 790
Query: 466 CVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVC--SPQTGACTCTPGWHGAHCQL- 522
C+C G+Q C P SC A C + A C SPQ C C G+ G CQ
Sbjct: 791 CLCAMGFQGPRCEGKLRP-----SC-ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTL 844
Query: 523 -------PCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHL---SCPEGLW 572
PCP+ C H C C GW G C+L SC +
Sbjct: 845 MDLCAQKPCPRNSH---CLQTGPSFH----------CLCLQGWTGPLCNLPLSSCQKAAL 891
Query: 573 GVNCSNTCTCKNGGTCLPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC 630
+ C NGG C+ + C C PGF+G CQ P C C N + C
Sbjct: 892 SQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNP------CESRPCQNGATC 945
Query: 631 --HPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS--CICPLGW 686
PS C C G+ G +CS+ + Q+ CH+ GTC P+ G C CP G+
Sbjct: 946 MAQPSGYLCQCAPGYDGQNCSKEL-------DACQSQPCHNHGTCTPKPGGFHCACPPGF 998
Query: 687 TGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGA--CVCPPGHSGAPCRIGI 738
G C G QPC CH A C C PGH+G C + I
Sbjct: 999 VGLRCE-----GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI 1047
Score = 239 bits (609), Expect = 1e-62
Identities = 227/807 (28%), Positives = 287/807 (35%), Gaps = 214/807 (26%)
Query: 88 LQCCHGFYESRGFCVPLCAQECVHG-RCVA----PNQCQCVPGWRGDDCSSECAPGMWGP 142
L C RG + C +G C++ CQC PG+ G+ C +
Sbjct: 14 LLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC-------QFPD 66
Query: 143 QCDKPCSCGNNSSCD----PKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPC 198
C C N SC G+ S PS L P+ L C PG+ G CQ + + PC
Sbjct: 67 PCQNAQLCQNGGSCQALLPAPLGLPSSPSPL-TPSFLCTCLPGFTGERCQAKLE---DPC 122
Query: 199 DP----QTGACFCPAERTGPSCDVSCSQGTSGFFCP-----STHSCQNGGVFQT--PQGS 247
P + G C A P C SC G +G C S + C NGGV PQ
Sbjct: 123 PPSFCSKRGRCHIQASGR-PQC--SCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQ 179
Query: 248 CSCPPGWMGTICSLPCPEGFHGPN-CSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREEC 306
C CPPG+ G C E F P C + CHN + QC C G G RC
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHN----TLGSFQCLCPVGQEGPRCELRA 235
Query: 307 -PVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
P G TC P+ CLC GF G C + PD CQ TC
Sbjct: 236 GPCPPRGCSNGGTCQLMPEKD--STFHLCLCPPGFIGPDC--EVNPDNCVSHQCQNGGTC 291
Query: 366 DREHSLSCHPMNGECSCLPGWAGLHCNESCPQ-DTHGPGCQEHCLCLHGGVCQATSGL-- 422
+ L + C C W G C+E + +T GP H C +GG CQ ++G
Sbjct: 292 --QDGLDTY----TCLCPETWTGWDCSEDVDECETQGP---PH--CRNGGTCQNSAGSFH 340
Query: 423 CQCAPGYTGPHC-------------------------ASLCPPDTYGVNCSARCSCENAI 457
C C G+ G C + LCPP G+ C E+
Sbjct: 341 CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGL----LCHLEDMC 396
Query: 458 ACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQ-----------CAHEAVC--SP 504
P G+ C G+ C PG G +C+ C H C +P
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTP 456
Query: 505 QTGACTCTPGWHGAHCQLP-------------------------CPKGQFGE-------G 532
+ C C PG+ G+ C+ CP G G+
Sbjct: 457 GSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNE 516
Query: 533 CASRCDCDHSDGCDPVHG-RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPE 591
CAS +H+D D ++G +C C G+ G RC E + C NGG C +
Sbjct: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDE-------CRSSPCANGGQCQDQ 569
Query: 592 NG--NCVCAPGFRGPSCQRSCQPGRYGKRCV--PCKCANHSFCHPSNGTCYCLAGWTGPD 647
G +C C PGF GP CQ C+ PC P C C +G+TG
Sbjct: 570 PGAFHCKCLPGFEGPRCQTEVD------ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 648 CSQP-----------------------CPPGHWGENCA---QTCQCHHGGTCHPQDGSCI 681
C P CP G G CA C CHHG H Q SC+
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHG---HCQRSSCV 678
Query: 682 CPLGWTGHHC---LEG----------------------CPLGTFGANCSQ---PCQCGP- 712
C +GWTG C L G CP G G CS+ C GP
Sbjct: 679 CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738
Query: 713 --GEKCHPETGA--CVCPPGHSGAPCR 735
G C+P G C CPP H+G C+
Sbjct: 739 LNGGSCNPSPGGYYCTCPPSHTGPQCQ 765
Score = 214 bits (544), Expect = 4e-55
Identities = 217/775 (28%), Positives = 260/775 (33%), Gaps = 213/775 (27%)
Query: 99 GFCVPLCAQ---ECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDK--------P 147
GF C + EC C QCQ PG +C PG GP+C P
Sbjct: 542 GFSGTRCEEDIDECRSSPCANGGQCQDQPG----AFHCKCLPGFEGPRCQTEVDECLSDP 597
Query: 148 CSCGNNSSCDPKSGVCSCPSG---------LQPPNCLQP--------------CTPGYYG 184
C G + P + C CPSG L PN QP C G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDG--S 655
Query: 185 PAC---QFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVF 241
P C + C CH C Q +C C TGP C+ C S G +
Sbjct: 656 PGCAPPEDNCTCHHGHC--QRSSCVCDVGWTGPECEAELGG------CISAPCAHGGTCY 707
Query: 242 QTPQG-SCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTG--QCRCAPGYT 298
P G +C+CP G+ G CS GP C NGG C+ G C C P +T
Sbjct: 708 PQPSGYNCTCPTGYTGPTCSEEMTACHSGP-------CLNGGSCNPSPGGYYCTCPPSHT 760
Query: 299 GDRCREECPVGRFGQDCAETCDCAPDARCF--PANGACLCEHGFTGDRCTDRL------- 349
G +C+ D + C C P +CLC GF G RC +L
Sbjct: 761 GPQCQTST-------DYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADS 813
Query: 350 ------------------CPDGFYGLSCQ------APCTCDRE-HSLSCHPMNGECSCLP 384
CP G+ G SCQ A C R H L P + C CL
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP-SFHCLCLQ 872
Query: 385 GWAGLHCNES-----------------------------------CPQDTHGPGCQEHCL 409
GW G CN CP G CQ+H
Sbjct: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVN 932
Query: 410 ------CLHGGVCQATSG--LCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSP 461
C +G C A LCQCAPGY G +C+ ++ C N C+P
Sbjct: 933 PCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSK-------ELDACQSQPCHNHGTCTP 985
Query: 462 IDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQ 521
G C CPPG G C + C P TG C + +CQ
Sbjct: 986 KPGGFHC-----------ACPPGFVGLRCEGDVDECLDQPCHP-TGTAACHSLANAFYCQ 1033
Query: 522 LPCPKGQFGEGCASRCDCDHSDGCDPVH-GRCQCQAGW-MGARCHLSCPEGLWGVNCSNT 579
C G G+ C D HS C H G C+ AG +G CH CP+G G CS+
Sbjct: 1034 --CLPGHTGQWCEVEIDPCHSQPC--FHGGTCEATAGSPLGFICH--CPKGFEGPTCSHR 1087
Query: 580 CT------CKNGGTCLPE-----NGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHS 628
C +GG CLP C C G+ GP C P G P C
Sbjct: 1088 APSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP---PSPCL--- 1141
Query: 629 FCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENC----AQTCQCHHG-GTCHPQDGSCICP 683
NG+C G GP CP G C A+ C+ G G C D C P
Sbjct: 1142 ----YNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC---DAGCSGP 1194
Query: 684 LG-WTGHHCLEGCPLGTFGANCSQPC-------QCGP---GEKCHPETGACVCPP 727
G W G C G P G C QC P E+C + C PP
Sbjct: 1195 GGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPP 1249
Score = 202 bits (513), Expect = 2e-51
Identities = 197/750 (26%), Positives = 248/750 (33%), Gaps = 197/750 (26%)
Query: 47 FSLLPS----EPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQC-CHGFYESRGFC 101
F L PS + CE P P+ C QP +Q+ K D + + C C S G
Sbjct: 612 FCLCPSGFTGQLCEVPLCAPNLC-QP--------KQICK-DQKDKANCLCPD--GSPGCA 659
Query: 102 VPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSE-------------------------CA 136
P C HG C + C C GW G +C +E C
Sbjct: 660 PPEDNCTCHHGHCQR-SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
Query: 137 PGMWGPQCDKPCS------CGNNSSCDPKSG--VCSCPSGLQPPNCLQP----------- 177
G GP C + + C N SC+P G C+CP P C
Sbjct: 719 TGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFN 778
Query: 178 --------------CTPGYYGPACQ--FRCQCHGAPC--------DPQTGACFCPAERTG 213
C G+ GP C+ R C +PC PQ C CP TG
Sbjct: 779 GGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTG 838
Query: 214 PSCDVS---CSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLP---CPEGF 267
SC C+Q CP C G P C C GW G +C+LP C +
Sbjct: 839 GSCQTLMDLCAQKP----CPRNSHCLQTG----PSFHCLCLQGWTGPLCNLPLSSCQKAA 890
Query: 268 HGPNCSQECRCHNGGLCDRFTGQ--CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDA 325
CHNGGLC C C PG+ G C++ + E+ C A
Sbjct: 891 LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV-------NPCESRPCQNGA 943
Query: 326 RCF--PANGACLCEHGFTGDRCTDRL------------------------CPDGFYGLSC 359
C P+ C C G+ G C+ L CP GF GL C
Sbjct: 944 TCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRC 1003
Query: 360 QAPCT------CDREHSLSCHPMNGE--CSCLPGWAGLHCNESCPQDTHGPGCQEHCLCL 411
+ C + +CH + C CLPG G C P C
Sbjct: 1004 EGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQP-------CF 1056
Query: 412 HGGVCQATSG-----LCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSP----- 461
HGG C+AT+G +C C G+ GP C+ P +C C + C P
Sbjct: 1057 HGGTCEATAGSPLGFICHCPKGFEGPTCSHRAP------SCGFH-HCHHGGLCLPSPKPG 1109
Query: 462 IDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGA------CTCTPGW 515
C C G+ +C P P C C + CS TG C+C
Sbjct: 1110 FPPRCACLSGYGGPDCLTPPAPK----GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSS 1165
Query: 516 HGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVN 575
G CQ P KG G CD GC G W G C L P+ G
Sbjct: 1166 PGPRCQKPGAKGCEGRSGDGACDA----GCSGPGGN------WDGGDCSLGVPDPWKGCP 1215
Query: 576 CSNTCTCK-NGGTCLPENGNCVCAPGFRGPSCQR--SCQPGRYGKRCVPCKCANHSFCHP 632
+ C G C P+ + C F G C+ +C P Y + C H C
Sbjct: 1216 SHSRCWLLFRDGQCHPQCDSEECL--FDGYDCETPPACTPA-YDQYCHDHFHNGH--CEK 1270
Query: 633 SNGTCYCLAGWTGPDCSQPCPPGHWGENCA 662
T C GW G DC WG + A
Sbjct: 1271 GCNTAEC--GWDGGDCRPEDGDPEWGPSLA 1298
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 236 bits (601), Expect = 1e-61
Identities = 226/838 (26%), Positives = 293/838 (34%), Gaps = 251/838 (29%)
Query: 99 GFCVPLCAQE--------CVHGRC---VAPNQCQCVPGWRGDDC---SSECAPGMWGPQC 144
G+ P C E CVHG C + +C C PGW G +C ++EC
Sbjct: 707 GYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN------ 760
Query: 145 DKPCSCGNNSSC-DPKSG-VCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQT 202
C N +C D SG VC+C G PNC P C G D
Sbjct: 761 ----PCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNP-----CLNQGTCIDDVA 811
Query: 203 G-ACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQG----SCSCPPGWMGT 257
G C C TG +C+V + PS C+NGG + + SC CP GW G
Sbjct: 812 GYKCNCLLPYTGATCEVVLAP-----CAPSP--CRNGGECRQSEDYESFSCVCPTGWQGQ 864
Query: 258 ICSLP-------------------------CPEGFHGPNCS---QECR---CHNGGLCDR 286
C + C G+ G NC +CR CHNGG C
Sbjct: 865 TCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTD 924
Query: 287 F--TGQCRCAPGYTGDRCREE-------------------------CPVGRFGQDCAETC 319
T C C PG+ G C E+ CP G G C
Sbjct: 925 GINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNT 984
Query: 320 DCAPDARCFPANGA----------CLCEHGFTGDRCTDRL-------------------- 349
++ CF NG CLC GFTG C +
Sbjct: 985 PDCTESSCF--NGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGS 1042
Query: 350 ----CPDGFYGLSCQ--------APCT----CDREHSLSCHPMNGECSCLPGWAGLHCNE 393
CP G+ G +CQ +PC C + H+ C C GW GL+C+
Sbjct: 1043 YRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHT------QYRCECPSGWTGLYCDV 1096
Query: 394 ---SCPQDTHGPGCQEHCLCLHGGVCQATSGL--CQCAPGYTGPHCASL---CPPDTY-- 443
SC G LC HGG+C C+C GYTG +C L C P
Sbjct: 1097 PSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQN 1156
Query: 444 GVNCSA-----RCSCE---NAIACSPIDGECVCKEGWQRGNC-------SVPCPPGTWGF 488
G C+ C C + + CS EC+ G C CP GT G
Sbjct: 1157 GATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGV 1216
Query: 489 SC--------------NASCQCAHEAVCSPQTG--ACTCTPGWHGAHCQLPCPKGQFGEG 532
C + S +C + C Q G +CTC PG+ G C+ G E
Sbjct: 1217 HCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----GDVNEC 1271
Query: 533 CASRCDCDHSDGC----DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC 588
++ CD + C + H C+C+AG G RC +N CKNGGTC
Sbjct: 1272 LSNPCDARGTQNCVQRVNDFH--CECRAGHTGRRCESV-------INGCKGKPCKNGGTC 1322
Query: 589 LPENGN-----CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HPSNGTCYCLA 641
+ C C GF G +C+ + C +C N C P + TC CL
Sbjct: 1323 AVASNTARGFICKCPAGFEGATCENDA------RTCGSLRCLNGGTCISGPRSPTCLCLG 1376
Query: 642 GWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS----CICPLGWTG--HHCLEGC 695
+TGP+C P G N C++ GTC P S C+CP + G H L+
Sbjct: 1377 PFTGPECQFPASSPCLGGN-----PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYS 1431
Query: 696 PLGTFGANCSQP----------CQCGPGEK-CHPETGACVCPPGHSGAPCRIGIQEPF 742
G G + P CQ G K C + C G G C + +P+
Sbjct: 1432 FGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHAC--GWDGGDCSLNFNDPW 1487
Score = 235 bits (599), Expect = 2e-61
Identities = 202/708 (28%), Positives = 264/708 (37%), Gaps = 183/708 (25%)
Query: 120 CQCVPGWRGDDCSS-------------------------ECAPGMWGPQC-------DKP 147
C CV GW G+DCS EC G G C P
Sbjct: 321 CVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNP 380
Query: 148 CSCGNNSSCDPKSG--VCSCPSGLQPPNCLQ---PCTPGYYGPACQFRCQCHGAPCDPQT 202
C+ G+N +P +G +C+CPSG P C Q C+ G C+ H C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG--ANPCE-----HAGKCINTL 433
Query: 203 GA--CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGG--VFQTPQGSCSCPPGWMGTI 258
G+ C C TGP C++ ++ S + CQN + Q + C C PG+ G
Sbjct: 434 GSFECQCLQGYTGPRCEIDVNECVS-------NPCQNDATCLDQIGEFQCICMPGYEGVH 486
Query: 259 CSLPCPEGFHGPNCSQECRCHNGGLCDRFTG-QCRCAPGYTGDRCREECPVGRFGQDCAE 317
C + E C+ HNG D+ QC C G+TG C+ + +CA
Sbjct: 487 CEVNTDE------CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDV------DECAS 534
Query: 318 TCDCAPDARCF--PANGACLCEHGFTGDRC---TDRLCPDGFYGLSCQAPCTCDREHSLS 372
T C A+C P C+C G+TG C D PD PC H S
Sbjct: 535 T-PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPD---------PC-----HYGS 579
Query: 373 CHP--MNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG--LCQCAPG 428
C C C PG+ G HC + + + P C HGG CQ LC C G
Sbjct: 580 CKDGVATFTCLCRPGYTGHHCETNINECSSQP-------CRHGGTCQDRDNAYLCFCLKG 632
Query: 429 YTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG-ECVCKEGWQRGNCSVPCPPGTWG 487
TGP+C ++ A C++ IDG EC C+ PG G
Sbjct: 633 TTGPNC-------EINLDDCASSPCDSGTCLDKIDGYECACE-------------PGYTG 672
Query: 488 FSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDP 547
CN + E +P TC G +G C+ CP+G C S + +S+ C
Sbjct: 673 SMCNINID---ECAGNPCHNGGTCEDGINGFTCR--CPEGYHDPTCLSEVNECNSNPC-- 725
Query: 548 VHG---------RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC--LPENGNCV 596
VHG +C C GW G C ++ E C + C NGGTC + C
Sbjct: 726 VHGACRDSLNGYKCDCDPGWSGTNCDINNNE------CESN-PCVNGGTCKDMTSGYVCT 778
Query: 597 CAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HPSNGTCYCLAGWTGPDCS---QP 651
C GF GP+CQ + C C N C + C CL +TG C P
Sbjct: 779 CREGFSGPNCQTNI------NECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP 832
Query: 652 CPPGHWGENCAQTCQCHHGGTCHPQDG----SCICPLGWTGHHC---LEGCPLG--TFGA 702
C P C +GG C + SC+CP GW G C + C L GA
Sbjct: 833 CAPS----------PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGA 882
Query: 703 NCSQP-------CQCG-PGEKCHPETGACVCPPGHSGAPCRIGIQEPF 742
+C CQ G G C + C P H+G C GI F
Sbjct: 883 SCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 930
Score = 230 bits (586), Expect = 6e-60
Identities = 207/702 (29%), Positives = 272/702 (38%), Gaps = 172/702 (24%)
Query: 99 GFCVPLCA----QECVHGRC----------VAPNQCQCVPGWRGDDCSSECAPGMWGPQC 144
GF PLC C+ C + +C+C PGW G C P
Sbjct: 92 GFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA------DPCA 145
Query: 145 DKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA 204
PC+ G S +C CP P C Q P C+ HG C + G+
Sbjct: 146 SNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGL---CR-HGGTCHNEVGS 201
Query: 205 --CFCPAERTGPSCD---VSCSQGTSGFFCPSTHSCQNGGVFQTPQG----SCSCPPGWM 255
C C A TGP+C+ V CS PS CQNGG + P G C+C PG+
Sbjct: 202 YRCVCRATHTGPNCERPYVPCS--------PS--PCQNGGTCR-PTGDVTHECACLPGFT 250
Query: 256 GTICSL---PCPEGFHGPNCSQECRCHNGGLC--DRFTGQCRCAPGYTGDRCREECPVGR 310
G C CP G NC NGG C T CRC P +TG C E+
Sbjct: 251 GQNCEENIDDCP----GNNCK------NGGACVDGVNTYNCRCPPEWTGQYCTED----- 295
Query: 311 FGQDCAETCDCAPDA-----RCFPANGA--CLCEHGFTGDRCTDRLCPDGFYGLSCQAPC 363
+ C P+A C +G C+C +G+TG+ C++ + D +C
Sbjct: 296 -----VDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI--DDCASAACFHGA 348
Query: 364 TC-DREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQAT--- 419
TC DR S C +G L H N++C + C G C
Sbjct: 349 TCHDRVASFYCECPHGRTGLL-----CHLNDACISNP----------CNEGSNCDTNPVN 393
Query: 420 -SGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG--ECVCKEGWQRGN 476
+C C GYTGP C+ + G N CE+A C G EC C +G+
Sbjct: 394 GKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGSFECQCLQGYTGPR 448
Query: 477 CSVPCPPGTWGFSCNASCQCAHEAVCSPQTG--ACTCTPGWHGAHCQLPCPKGQFGEGCA 534
C + C S C ++A C Q G C C PG+ G HC++ + CA
Sbjct: 449 CEIDVN------EC-VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNT------DECA 495
Query: 535 SRCDCDHSDGC-DPVHG-RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCL--P 590
S C H+ C D ++ +C+C G+ G C E C++T CKNG CL P
Sbjct: 496 S-SPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDE------CAST-PCKNGAKCLDGP 547
Query: 591 ENGNCVCAPGFRGPSCQ---RSCQPG--RYGKRCVPCKCANHSFCHPSNGTCYCLAGWTG 645
CVC G+ G C+ C P YG CK +F TC C G+TG
Sbjct: 548 NTYTCVCTEGYTGTHCEVDIDECDPDPCHYGS----CKDGVATF------TCLCRPGYTG 597
Query: 646 PDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS--CICPLGWTGHHC---LEGCPLGTF 700
C N + C HGGTC +D + C C G TG +C L+ C
Sbjct: 598 HHCET-------NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDC----- 645
Query: 701 GANCSQPCQCGPGEKCHPETGA--CVCPPGHSGAPCRIGIQE 740
S PC G C + C C PG++G+ C I I E
Sbjct: 646 ---ASSPCDSG---TCLDKIDGYECACEPGYTGSMCNINIDE 681
Score = 217 bits (552), Expect = 5e-56
Identities = 180/635 (28%), Positives = 245/635 (38%), Gaps = 121/635 (19%)
Query: 141 GPQCDKPC-SCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCD 199
GP+C +P +C N C+ +G +C C + GP CQ C PC
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACV-----------CGGAFVGPRCQDPNPCLSTPCK 69
Query: 200 PQTGACFCPAERTGPSCDVSCSQGTSGFFCPS-------THSCQNGG---VFQTPQGSCS 249
G C R SC+ G SG C + T+ C+NGG + + C
Sbjct: 70 -NAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCR 128
Query: 250 CPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQ--CRCAPGYTGDRCREECP 307
CPPGW G C P C+ C NGG C F C C P + G CR++
Sbjct: 129 CPPGWSGKSCQQADP-------CASN-PCANGGQCLPFEASYICHCPPSFHGPTCRQD-- 178
Query: 308 VGRFGQDCAETCDCAPDARCFPANGA--CLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
V GQ C C G+ C+C TG C P +PC
Sbjct: 179 VNECGQKPGL---CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP------CSPSPC-- 227
Query: 366 DREHSLSCHP---MNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGL 422
++ +C P + EC+CLPG+ G +C E+ D G C+ C+ G +
Sbjct: 228 --QNGGTCRPTGDVTHECACLPGFTGQNCEENI-DDCPGNNCKNGGACVDG----VNTYN 280
Query: 423 CQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG--ECVCKEGWQRGNCSVP 480
C+C P +TG +C N +C+N C G CVC GW +CS
Sbjct: 281 CRCPPEWTGQYCTEDVDECQLMPN-----ACQNGGTCHNTHGGYNCVCVNGWTGEDCSEN 335
Query: 481 CPPGTWGFSCNASCQCAHEAVCSPQTGA--CTCTPGWHGAHCQLPCPKGQFGEGCASRCD 538
C AS C H A C + + C C G G C L + C S
Sbjct: 336 ID------DC-ASAACFHGATCHDRVASFYCECPHGRTGLLCHL-------NDACISN-P 380
Query: 539 CDHSDGCD--PVHGR--CQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGN 594
C+ CD PV+G+ C C +G+ G C E G N C++ G C+ G+
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGS 435
Query: 595 --CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGT--CYCLAGWTGPDCSQ 650
C C G+ GP C+ CV C N + C G C C+ G+ G C
Sbjct: 436 FECQCLQGYTGPRCEIDVN------ECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEV 489
Query: 651 PCPPGHWGENCAQTCQCHHGGTCHPQ--DGSCICPLGWTGHHC---LEGCPLGTFGANCS 705
+ CA + C H G C + + C CP G+TGH C ++ C S
Sbjct: 490 NT------DECASS-PCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDEC--------AS 534
Query: 706 QPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQE 740
PC+ G P T CVC G++G C + I E
Sbjct: 535 TPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 215 bits (548), Expect = 2e-55
Identities = 223/832 (26%), Positives = 283/832 (34%), Gaps = 258/832 (31%)
Query: 120 CQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCD--PKSGVCSCPSGLQ------- 170
C+C+ G+ G C ++ +CD P C + +C P S C CP G
Sbjct: 168 CKCLTGFTGQKCETDVN------ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL 221
Query: 171 -----PPNCLQP--------------CTPGYYGPACQ--------FRCQCHGAPCDP-QT 202
P C+ C PG+ G C+ RCQ G D T
Sbjct: 222 YVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNT 281
Query: 203 GACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS--CSCPPGWMGTICS 260
C CP + TG C + ++CQNGG G C C GW G CS
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLL-----QPNACQNGGTCANRNGGYGCVCVNGWSGDDCS 336
Query: 261 -------------------------LPCPEGFHGPNCSQECRC-----HNGGLCDR--FT 288
CPEG G C + C H G LCD
Sbjct: 337 ENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLN 396
Query: 289 GQ--CRCAPGYTGDRCRE----------------------------ECPVGRFGQDC--- 315
GQ C C GY G C E EC G G C
Sbjct: 397 GQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMD 456
Query: 316 ---AETCDCAPDARCFPANGA--CLCEHGFTG------------------DRCTDR---- 348
+ C DA C G CLC GF G +C D+
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRF 516
Query: 349 --LCPDGFYGLSCQ--------APCTCDREHSLSC--HPMNGECSCLPGWAGLHCNESC- 395
LCP GF G CQ PC + C HP EC C G+ G+ C E+
Sbjct: 517 QCLCPPGFTGPVCQIDIDDCSSTPCL----NGAKCIDHPNGYECQCATGFTGVLCEENID 572
Query: 396 ---PQDTHGPGCQEH-----CLC---LHGGVCQATSGLCQCAPGYTGPHCASL------- 437
P H CQ+ C+C G +C C +P C L
Sbjct: 573 NCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCN 632
Query: 438 CPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCA 497
C P T GVNC + C I G +C +G R +C C PG G CN
Sbjct: 633 CQPGTSGVNCEINFDDCASNPC--IHG--ICMDGINRYSCV--CSPGFTGQRCNIDID-- 684
Query: 498 HEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHG------- 550
E +P TC G +G C CP+G C S+ + S+ C +HG
Sbjct: 685 -ECASNPCRKGATCINGVNGFRCI--CPEGPHHPSCYSQVNECLSNPC--IHGNCTGGLS 739
Query: 551 --RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC--LPENGNCVCAPGFRGPSC 606
+C C AGW+G C + E L SN C +NGGTC L C C GF+G +C
Sbjct: 740 GYKCLCDAGWVGINCEVDKNECL-----SNPC--QNGGTCDNLVNGYRCTCKKGFKGYNC 792
Query: 607 QRSCQPGRYGKRCVPCKCANHSFCHP--SNGTCYCLAGWTGPDCSQP------------- 651
Q + C C N C S TC+C+ +TG +C
Sbjct: 793 QVNID------ECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAA 846
Query: 652 --------------CPPGHWGENCA---QTC---QCHHGGTCHPQDGS--CICPLGWTGH 689
C PG G+ C C C + G CH GS C CP G++G
Sbjct: 847 VCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGM 906
Query: 690 HCLEGCPLGTFGANC-SQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQE 740
C E +C + PCQ G T +C+C PG +G C+ + E
Sbjct: 907 DCEEDID------DCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE 952
Score = 211 bits (538), Expect = 2e-54
Identities = 216/837 (25%), Positives = 291/837 (34%), Gaps = 280/837 (33%)
Query: 120 CQCVPGWRGDDCSSE-------------------------CAPGMWGPQC-------DKP 147
C CV GW GDDCS C G G C P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 148 CSCGNNSSCDPKSG--VCSCPSGLQPPNCLQ----------------------------P 177
C G +P +G +C+CP G + +C +
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
Query: 178 CTPGYYGPACQFRC-QCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP------ 230
C GY GP C+ +CH PC C + G +C C G G C
Sbjct: 444 CLKGYAGPRCEMDINECHSDPCQ---NDATCLDKIGGFTC--LCMPGFKGVHCELEINEC 498
Query: 231 STHSCQNGG--VFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLC-DRF 287
++ C N G V + + C CPPG+ G +C + + CS C NG C D
Sbjct: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDD------CS-STPCLNGAKCIDHP 551
Query: 288 TG-QCRCAPGYTGDRCREE------------------------CPVGRFGQDCAETCD-- 320
G +C+CA G+TG C E C G G C++ D
Sbjct: 552 NGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDEC 611
Query: 321 ----CAPDARCFP-ANG-ACLCEHGFTG------------DRCTDRLCPDGFYGLSCQAP 362
C D RC NG C C+ G +G + C +C DG SC
Sbjct: 612 YSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCS 671
Query: 363 -------CTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQ---EHCL--- 409
C D + S +P +C+ G G C CP+ H P C CL
Sbjct: 672 PGFTGQRCNIDIDECAS-NPCRKGATCINGVNGFRC--ICPEGPHHPSCYSQVNECLSNP 728
Query: 410 CLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSA---RC---SCENAIACSPID 463
C+HG C G +G C LC G+NC C C+N C +
Sbjct: 729 CIHG----------NCTGGLSGYKC--LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLV 776
Query: 464 G--ECVCKEGWQRGNCSV--------PC-PPGTW-----GFSCNA-------SCQ----- 495
C CK+G++ NC V PC GT G++C+ +CQ
Sbjct: 777 NGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAP 836
Query: 496 -----CAHEAVC--SP--QTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCD 546
C + AVC SP ++ C C PGW G C + + C S+ C + C
Sbjct: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI------DECISK-PCMNHGLCH 889
Query: 547 PVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTC------TCKNGGTCLP--ENGNCVCA 598
G C+ CP G G++C C+NGG+C+ +C+C
Sbjct: 890 NTQGSYMCE-----------CPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCL 938
Query: 599 PGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HPSNGTCYCLAGWTGPDCSQPCPPGH 656
PGF G CQ C+ C N C + ++ TC C AG+ G C
Sbjct: 939 PGFTGDKCQTDM------NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI---- 988
Query: 657 WGENCAQTCQCHHGGTCHPQDG----SCICPLGWTGHHCLE------------------- 693
C ++ C +GGTC DG SC+CP+G+TG CL
Sbjct: 989 --NECTES-SCFNGGTC--VDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDG 1043
Query: 694 ------GCPLGTFGANCS--------QPCQCGPGEKCHPETGACVCPPGHSGAPCRI 736
CPLG G NC PC+ C+CP G +GA C +
Sbjct: 1044 LGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDV 1100
Score = 207 bits (526), Expect = 5e-53
Identities = 206/762 (27%), Positives = 269/762 (35%), Gaps = 222/762 (29%)
Query: 109 CVHGRC---VAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDP--KSGVC 163
C+HG C ++ +C C GW G +C + + P C N +CD C
Sbjct: 729 CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNP-------CQNGGTCDNLVNGYRC 781
Query: 164 SCPSGLQPPNCL--------QPCT---------PGYYG----PACQFRCQCHGAPCDPQT 202
+C G + NC PC GY P CQ APC P
Sbjct: 782 TCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNP 841
Query: 203 --GACFCPAERTGPSCDVSCSQGTSGFFCPS------THSCQNGGVFQTPQGS--CSCPP 252
A C S C+ G G C + C N G+ QGS C CPP
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPP 901
Query: 253 GWMGTICSLPCPEGFHGPNCSQECRCHNGGLC--DRFTGQCRCAPGYTGDRCREE----- 305
G+ G C + P C NGG C T C C PG+TGD+C+ +
Sbjct: 902 GFSGMDCEEDIDDCLANP-------CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECL 954
Query: 306 --------------------CPVGRFGQDCAETCDCAPDARCFPANG----------ACL 335
C G G C + ++ CF NG +CL
Sbjct: 955 SEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCF--NGGTCVDGINSFSCL 1012
Query: 336 CEHGFTGDRCTDRL------------------------CPDGFYGLSCQ--------APC 363
C GFTG C + CP G+ G +CQ +PC
Sbjct: 1013 CPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPC 1072
Query: 364 ----TCDREHSLSCHPMNGECSCLPGWAGLHC---NESCPQDTHGPGCQEHCLCLHGGVC 416
TC ++ + S +C C GWAG +C N SC G LC H GVC
Sbjct: 1073 KNKGTCVQKKAES------QCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVC 1126
Query: 417 --QATSGLCQCAPGYTGPHCASLCP-----PDTYGVNCSA-----RCSCE---NAIACSP 461
+ CQC GYTG +C P +G CS RC C + C
Sbjct: 1127 INAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEY 1186
Query: 462 IDGECVCKEGWQRGNC-------SVPCPPGTWGFSCNASCQ-------CAHEAVCSPQTG 507
EC + G C CPPGT G C + C + C + G
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIG 1246
Query: 508 --ACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGR--CQCQAGWMGARC 563
+C C PG+ G C+ G E ++ C + S C + C C++ + G C
Sbjct: 1247 GYSCRCLPGFAGERCE-----GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
Query: 564 HLS---CPEGLWGVNCSNTCTCKNGGTC-----LPENGNCVCAPGFRGPSCQRSC--QPG 613
CP+ C NGGTC +P+ C C PGF G CQ SC
Sbjct: 1302 ETFVDVCPQ----------MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKC 1351
Query: 614 RYGKRCVPCKCANHSFCHPSNG-TCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT 672
R G++CV H ++G C+C + DC C + C HGG+
Sbjct: 1352 RKGEQCV----------HTASGPRCFCP---SPRDCESGC----------ASSPCQHGGS 1388
Query: 673 CHPQDG----SCICPLGWTGHHC-LEGCPLGTFGANC-SQPC 708
CHPQ SC C ++G C L P T A C SQ C
Sbjct: 1389 CHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYC 1430
Score = 201 bits (512), Expect = 2e-51
Identities = 212/839 (25%), Positives = 277/839 (33%), Gaps = 266/839 (31%)
Query: 101 CVPLCAQECVH-GRCVAPN---QCQCVPGWRGDDCSSE---------------------- 134
C + C H G+CV + C+C+ G+ G C +
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGF 478
Query: 135 ---CAPGMWGPQCDKPCS------CGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGP 185
C PG G C+ + C NN C K C C PG+ GP
Sbjct: 479 TCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL-----------CPPGFTGP 527
Query: 186 ACQFRCQ-CHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFC----------PSTHS 234
CQ C PC C G C C+ G +G C P H
Sbjct: 528 VCQIDIDDCSSTPC---LNGAKCIDHPNGYECQ--CATGFTGVLCEENIDNCDPDPCHHG 582
Query: 235 -CQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQ----------ECRCHNG-- 281
CQ+G +C C PG+MG ICS E + P + +C C G
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTS 638
Query: 282 ------------------GLC----DRFTGQCRCAPGYTGDRCR---EECPVG--RFGQD 314
G+C +R++ C C+PG+TG RC +EC R G
Sbjct: 639 GVNCEINFDDCASNPCIHGICMDGINRYS--CVCSPGFTGQRCNIDIDECASNPCRKGAT 696
Query: 315 CAE-----TCDCAPDAR---CFPANGACL--------CEHGFTGDRCTDRLCPDGFYGLS 358
C C C C+ CL C G +G +C LC G+ G++
Sbjct: 697 CINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC---LCDAGWVGIN 753
Query: 359 CQAPCTCDREHSLSCHPMNG----------ECSCLPGWAGLHCNESCPQDTHGPGCQEHC 408
C+ D+ LS NG C+C G+ G +C + + P
Sbjct: 754 CEV----DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNP------ 803
Query: 409 LCLHGGVC--QATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG-- 464
CL+ G C + C C YTG +C ++ P CS CENA C
Sbjct: 804 -CLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAP------CSPN-PCENAAVCKESPNFE 855
Query: 465 --ECVCKEGWQRGNCSVP-------------------------CPPGTWGFSCNAS---- 493
C+C GWQ C++ CPPG G C
Sbjct: 856 SYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDC 915
Query: 494 ----CQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGC-DPV 548
CQ + T +C C PG+ G CQ + C S C + C D V
Sbjct: 916 LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE------CLSE-PCKNGGTCSDYV 968
Query: 549 HG-RCQCQAGWMGARCHLSCPEGLWGVNCSNTCT---CKNGGTCLP--ENGNCVCAPGFR 602
+ C+CQAG+ G C N N CT C NGGTC+ + +C+C GF
Sbjct: 969 NSYTCKCQAGFDGVHCE----------NNINECTESSCFNGGTCVDGINSFSCLCPVGFT 1018
Query: 603 GPSCQR-------------------------SCQPGRYGKRCV---------PCKCANHS 628
G C SC G GK C PCK
Sbjct: 1019 GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC 1078
Query: 629 FCHPSNGTCYCLAGWTGPDCSQP---CPPGHWGENCAQTCQCHHGGTCHPQDGS--CICP 683
+ C C +GW G C P C C H G C + C CP
Sbjct: 1079 VQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCP 1138
Query: 684 LGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGA--CVCPPGHSGAPCRIGIQE 740
LG+TG +C E S PCQ G C G C C PG+ G C + E
Sbjct: 1139 LGYTGSYCEE-----QLDECASNPCQ--HGATCSDFIGGYRCECVPGYQGVNCEYEVDE 1190
Score = 192 bits (489), Expect = 1e-48
Identities = 214/842 (25%), Positives = 283/842 (33%), Gaps = 254/842 (30%)
Query: 109 CVHGRCVAPNQCQCVPGWRGDDC----------------------------SSECAPGMW 140
CV + C+C G+ G+DC C G
Sbjct: 79 CVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT 138
Query: 141 GPQC-------DKPCSCGNNSSCDPKSGVCSCPSGLQPPNC---LQPC-TPGY--YGPAC 187
G +C PC+ G+ + C C +G C + C PG+ +G C
Sbjct: 139 GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTC 198
Query: 188 -----QFRCQC----HGAPCDPQTGACFCPAERTGPSC--------DVSCSQGTSGFFCP 230
++CQC G CD C G +C + +C G G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE 258
Query: 231 ------STHSCQNGGVFQTPQG--SCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG 282
H CQNGGV +C CPP W G C+ E PN C NGG
Sbjct: 259 RNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNA-----CQNGG 313
Query: 283 LCDRFTG--QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFP--ANGACLCEH 338
C G C C G++GD C E DCA C P + C A+ +C+C
Sbjct: 314 TCANRNGGYGCVCVNGWSGDDCSENI------DDCA-FASCTPGSTCIDRVASFSCMCPE 366
Query: 339 GFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGE--CSCLPGWAGLHCNE--- 393
G G C D C CD +P+NG+ C+C G+ G C E
Sbjct: 367 GKAGLLCH---LDDACISNPCHKGALCD------TNPLNGQYICTCPQGYKGADCTEDVD 417
Query: 394 SCPQDTHGPGCQEHCLCLHGGVCQATSGL--CQCAPGYTGPHC----------------- 434
C P C H G C T G C+C GY GP C
Sbjct: 418 ECAMANSNP-------CEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDAT 470
Query: 435 --------ASLCPPDTYGVNCSARCS-CENAIACSPIDGECVCKEGWQRGNCSVPCPPGT 485
LC P GV+C + C++ + +G+CV K R C CPPG
Sbjct: 471 CLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVN--NGQCVDKV--NRFQCL--CPPGF 524
Query: 486 WGFSCN------ASCQCAHEAVC--SPQTGACTCTPGWHGAHCQL--------PCPKGQF 529
G C +S C + A C P C C G+ G C+ PC GQ
Sbjct: 525 TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQC 584
Query: 530 GEG----------------CASRCDCDHSDGC-------DPVHG-RCQCQAGWMGARCHL 565
+G C+ + D +S C D V+G +C CQ G G C +
Sbjct: 585 QDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI 644
Query: 566 SCPEGLWGVNCSNTCTCKNGGTCLP--ENGNCVCAPGFRGPSCQ--------------RS 609
+ + SN C G C+ +CVC+PGF G C +
Sbjct: 645 NFDD-----CASNPCI---HGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGAT 696
Query: 610 CQPGRYGKRCVPCKCANHSFCHPSNGTCY--------CLAGWTGPDCSQPCPPGHWGENC 661
C G G RC+ + +H C+ C C G +G C C G G NC
Sbjct: 697 CINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCL--CDAGWVGINC 754
Query: 662 ------AQTCQCHHGGTCH--PQDGSCICPLGWTGHHC---------------------L 692
+ C +GGTC C C G+ G++C +
Sbjct: 755 EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDI 814
Query: 693 EG----CPLGTFGANCS---QPCQCGPGEKC-------HPETGACVCPPGHSGAPCRIGI 738
G C L G NC PC P E + E+ C+C PG G C I I
Sbjct: 815 SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDI 874
Query: 739 QE 740
E
Sbjct: 875 DE 876
Score = 187 bits (475), Expect = 4e-47
Identities = 195/759 (25%), Positives = 253/759 (33%), Gaps = 209/759 (27%)
Query: 135 CAPGMWGPQC-DKPCSCGNNSSC---DPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR 190
CA QC D C N C +G C CP G C + P + R
Sbjct: 19 CAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ------HRDPCEKNR 72
Query: 191 CQCHGAPCDPQT----GACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGG---VFQT 243
CQ +G C Q C C + TG C S S C + C NGG +
Sbjct: 73 CQ-NGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-----CFVSRPCLNGGTCHMLSR 126
Query: 244 PQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQ--CRCAPGYTGDR 301
C+C G+ G C + C NG C Q C+C G+TG +
Sbjct: 127 DTYECTCQVGFTGKECQWT--------DACLSHPCANGSTCTTVANQFSCKCLTGFTGQK 178
Query: 302 CREECPVGRFGQDCAETCDCAPDARCF--PANGACLCEHGFTGDRCTDRLCPDGFYGLSC 359
C + +C C C P + C C GFTG C D Y
Sbjct: 179 CETDV------NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYC------DSLYVPCA 226
Query: 360 QAPC----TCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGV 415
+PC TC + + EC+CLPG+ G C + C H C +GGV
Sbjct: 227 PSPCVNGGTCRQTGDFTF-----ECNCLPGFEGSTCERNIDD------CPNH-RCQNGGV 274
Query: 416 CQ--ATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGE--CVCKEG 471
C + C+C P +TG C N +C+N C+ +G CVC G
Sbjct: 275 CVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN-----ACQNGGTCANRNGGYGCVCVNG 329
Query: 472 WQRGNCS--------VPCPPGTWGFS--CNASCQCAH--EAVCSPQTGACTCTPGWHGAH 519
W +CS C PG+ + SC C + AC P GA
Sbjct: 330 WSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGAL 389
Query: 520 CQL---------PCPKGQFGEGCASRCD---------CDHSDGCDPVHG--RCQCQAGWM 559
C CP+G G C D C+H+ C G C+C G+
Sbjct: 390 CDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA 449
Query: 560 GARCHLS-------------------------CPEGLWGVNCS---NTCT---CKNGGTC 588
G RC + C G GV+C N C C N G C
Sbjct: 450 GPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQC 509
Query: 589 LPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HPSNGTCYCLAGWT 644
+ + C+C PGF GP CQ C C N + C HP+ C C G+T
Sbjct: 510 VDKVNRFQCLCPPGFTGPVCQIDIDD------CSSTPCLNGAKCIDHPNGYECQCATGFT 563
Query: 645 GPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDG----SCICPLGWTGHHCLE------- 693
G C + +NC CHHG QDG +CIC G+ G C +
Sbjct: 564 GVLCEENI------DNCDPD-PCHHGQC---QDGIDSYTCICNPGYMGAICSDQIDECYS 613
Query: 694 ------------------GCPLGTFGANC--------SQPC--------------QCGPG 713
C GT G NC S PC C PG
Sbjct: 614 SPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPG 673
Query: 714 ---EKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTTP 749
++C+ + C P GA C G+ + P P
Sbjct: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP 712
Score = 138 bits (347), Expect = 3e-32
Identities = 147/528 (27%), Positives = 195/528 (36%), Gaps = 107/528 (20%)
Query: 102 VPLCAQE-CVH-GRCV---APNQCQCVPGWRGDDC-----SSECAPGMWGPQCDKPCSCG 151
V LC++ C + G CV A +QC C GW G C S + A G + C
Sbjct: 1064 VNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHS 1123
Query: 152 NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA--CFCPA 209
+ C CP G C + P CQ HGA C G C C
Sbjct: 1124 GVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP-----CQ-HGATCSDFIGGYRCECVP 1177
Query: 210 ERTGPSCDVSCSQGTSGFFCPSTHSCQNGG--VFQTPQGSCSCPPGWMGTICSLPCPEGF 267
G +C+ + C + CQNGG + CSCPPG G +C +
Sbjct: 1178 GYQGVNCEYEVDE------CQN-QPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCA 1230
Query: 268 HGPNCSQECRCHNGGLC-DRFTG-QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDA 325
GP+C NGG C DR G CRC PG+ G+RC G + + C
Sbjct: 1231 RGPHCL------NGGQCMDRIGGYSCRCLPGFAGERCE-----GDINECLSNPCSSEGSL 1279
Query: 326 RCFPANG--ACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNG-ECSC 382
C C+C FTG C + F + Q PC +++ + +G C C
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHC------ETFVDVCPQMPCLNGGTCAVASNMPDGFICRC 1333
Query: 383 LPGWAGLHCNESCPQ-----------DTHGP--------GCQEHCL---CLHGGVC---- 416
PG++G C SC Q GP C+ C C HGG C
Sbjct: 1334 PPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQR 1393
Query: 417 QATSGLCQCAPGYTGPHC-ASLCPPDTYGVNC-SARCS-------CE---NAIACSPIDG 464
Q CQCAP ++G C PP T C S C+ C+ N+ AC G
Sbjct: 1394 QPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGG 1453
Query: 465 ECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPC 524
+C NCS P P W + N QC + +C+ T C + CQ
Sbjct: 1454 DCSLTMENPWANCSSPLP--CWDYINN---QC--DELCN--TVECL----FDNFECQGNS 1500
Query: 525 PKGQFGEGCASRCDCDHSD-GCDPVHGRCQCQAGWMGARCHLSCPEGL 571
++ + CA +H D GC+ + GW G C PE L
Sbjct: 1501 KTCKYDKYCADHFKDNHCDQGCNSE------ECGWDGLDCAADQPENL 1542
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 214 bits (544), Expect = 4e-55
Identities = 182/622 (29%), Positives = 234/622 (37%), Gaps = 190/622 (30%)
Query: 191 CQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHS------CQNGGVFQTP 244
C C AP + + E S C+ G P+T C G F T
Sbjct: 111 CGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTE 170
Query: 245 QGSCSCPPGWMGTICSLP------------------CPEGFHGPNCSQ---ECRCHNGGL 283
C C PGW G CS P C +GF G +CSQ C++ G
Sbjct: 171 GCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGK 230
Query: 284 CDRFTGQCRCAPGYTGDRC-REECPV------------------GRFGQDCAETC---DC 321
C G C C GY G C RE CPV G G DC + +C
Sbjct: 231 C--VNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNC 288
Query: 322 APDARCFPANGACLCEHGFTGDRCTDRLCP-----------------DGFYGLSCQAPCT 364
RC C+C+ GFTG+ C++ +CP +GF G C P T
Sbjct: 289 YNRGRC--VENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKP-T 345
Query: 365 CDREHSLSCHPM----NGECSCLPGWAGLHCNES-CPQDTHGPGCQEHCLCLHGGVCQAT 419
C +CH G+C C G+AG+ C+E CP D H G +
Sbjct: 346 CPH----ACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRG-------------RCV 388
Query: 420 SGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCS- 478
G C+C G+TG C L P+ CS C ++G+CVC EG+ +CS
Sbjct: 389 DGRCECDDGFTGADCGELKCPN----GCSGHGRC--------VNGQCVCDEGYTGEDCSQ 436
Query: 479 VPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC-QLPCPKGQFGEGCASRC 537
+ CP C++ +C G C C G+ G C + CP
Sbjct: 437 LRCPN-----DCHSRGRCVE--------GKCVCEQGFKGYDCSDMSCPN----------- 472
Query: 538 DCDHSDGCDPVHGRCQCQAGWMGARCH-LSCPEGLWGVNCSNTCTCKNGGTCLPENGNCV 596
DC C V+G C C G+ G C CP C N G C+ +G CV
Sbjct: 473 DCHQHGRC--VNGMCVCDDGYTGEDCRDRQCPR-----------DCSNRGLCV--DGQCV 517
Query: 597 CAPGFRGPSC-QRSCQPGRYGK-RCVPCKCANHSFCHPSNGTCYCLAGWTGPDC-SQPCP 653
C GF GP C + SC +G+ RCV NG C C G+ G DC Q CP
Sbjct: 518 CEDGFTGPDCAELSCPNDCHGQGRCV-------------NGQCVCHEGFMGKDCKEQRCP 564
Query: 654 PGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHC-LEGCPLGTFGANCSQPCQCGP 712
CH G C DG CIC G+TG C CP ++C+ QC
Sbjct: 565 -----------SDCHGQGRC--VDGQCICHEGFTGLDCGQHSCP-----SDCNNLGQC-- 604
Query: 713 GEKCHPETGACVCPPGHSGAPC 734
+G C+C G+SG C
Sbjct: 605 ------VSGRCICNEGYSGEDC 620
Score = 199 bits (505), Expect = 1e-50
Identities = 167/559 (29%), Positives = 221/559 (39%), Gaps = 147/559 (26%)
Query: 150 CGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPA 209
C + + C C G + PNC +P PG C R +C G C C
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGN----CHLRGRCID-------GQCICDD 209
Query: 210 ERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGT-----ICSLPCP 264
TG C S CPS C + G + G C C G+ G IC +PC
Sbjct: 210 GFTGEDC--------SQLACPS--DCNDQG--KCVNGVCICFEGYAGADCSREICPVPCS 257
Query: 265 EGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREE---CPVGRFGQDCAETC-- 319
E HG C CH+G D Y RC E C G G+DC+E
Sbjct: 258 EE-HGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICP 316
Query: 320 -DCAPDARCFPANGACLCEHGFTGDRCTDRLCP-----------------DGFYGLSC-Q 360
DC RC NG C CE GFTG+ C CP +GF G+ C +
Sbjct: 317 NDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSE 374
Query: 361 APCTCDREHSLSCHPMNGECSCLPGWAGLHCNE-SCPQDTHGPGCQEHCLCLHGGVCQAT 419
C D + C ++G C C G+ G C E CP GC H C++G
Sbjct: 375 KRCPADCHNRGRC--VDGRCECDDGFTGADCGELKCPN-----GCSGHGRCVNGQ----- 422
Query: 420 SGLCQCAPGYTGPHCASL-CPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCS 478
C C GYTG C+ L CP D C +R C ++G+CVC++G++ +CS
Sbjct: 423 ---CVCDEGYTGEDCSQLRCPND-----CHSRGRC--------VEGKCVCEQGFKGYDCS 466
Query: 479 -VPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQ-LPCPKGQFGEGCASR 536
+ CP C+ +C + G C C G+ G C+ CP+
Sbjct: 467 DMSCPN-----DCHQHGRCVN--------GMCVCDDGYTGEDCRDRQCPR---------- 503
Query: 537 CDCDHSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKNGGTCLPENGNC 595
DC + C V G+C C+ G+ G C LSCP C G C+ NG C
Sbjct: 504 -DCSNRGLC--VDGQCVCEDGFTGPDCAELSCPND-----------CHGQGRCV--NGQC 547
Query: 596 VCAPGFRGPSC-QRSCQPGRYGK-RCVPCKCANH--------------SFCHPS----NG 635
VC GF G C ++ C +G+ RCV +C H S C+ +G
Sbjct: 548 VCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSG 607
Query: 636 TCYCLAGWTGPDCSQPCPP 654
C C G++G DCS+ PP
Sbjct: 608 RCICNEGYSGEDCSEVSPP 626
Score = 187 bits (475), Expect = 4e-47
Identities = 153/553 (27%), Positives = 214/553 (38%), Gaps = 160/553 (28%)
Query: 120 CQCVPGWRGDDCSSE------------------CAPGMWGPQCDK---PCSCGNNSSCDP 158
C C PGW+G +CS C G G C + P C + C
Sbjct: 174 CVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKC-- 231
Query: 159 KSGVCSCPSGLQPPNCLQ-----PCTPGYYGPACQFRCQCH----GAPCDPQTGACFCPA 209
+GVC C G +C + PC+ +G C CH G C+ C
Sbjct: 232 VNGVCICFEGYAGADCSREICPVPCSE-EHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYN 290
Query: 210 ERTGPSCDVSCSQGTSGFFCPS---THSCQNGGVFQTPQGSCSCPPGWMGTICSLP---- 262
+ C +G +G C + C + G + G+C C G+ G C P
Sbjct: 291 RGRCVENECVCDEGFTGEDCSELICPNDCFDRG--RCINGTCYCEEGFTGEDCGKPTCPH 348
Query: 263 --------------CPEGFHGPNCSQE---CRCHNGGLCDRFTGQCRCAPGYTGDRCRE- 304
C EGF G +CS++ CHN G C G+C C G+TG C E
Sbjct: 349 ACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRC--VDGRCECDDGFTGADCGEL 406
Query: 305 ECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCT 364
+CP G C+ RC NG C+C+ G+TG+ C+ CP+ C +
Sbjct: 407 KCPNG-----------CSGHGRC--VNGQCVCDEGYTGEDCSQLRCPN-----DCHSRGR 448
Query: 365 CDREHSLSCHPMNGECSCLPGWAGLHCNE-SCPQDTHGPGCQEHCLCLHGGVCQATSGLC 423
C + G+C C G+ G C++ SCP D C +H C+ +G+C
Sbjct: 449 C----------VEGKCVCEQGFKGYDCSDMSCPND-----CHQHGRCV--------NGMC 485
Query: 424 QCAPGYTGPHCAS-LCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCS-VPC 481
C GYTG C CP D CS R C +DG+CVC++G+ +C+ + C
Sbjct: 486 VCDDGYTGEDCRDRQCPRD-----CSNRGLC--------VDGQCVCEDGFTGPDCAELSC 532
Query: 482 PPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC-QLPCPKGQFGEGCASRCDCD 540
P C+ +C + G C C G+ G C + CP G+G RC
Sbjct: 533 PN-----DCHGQGRCVN--------GQCVCHEGFMGKDCKEQRCPSDCHGQG---RC--- 573
Query: 541 HSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAP 599
V G+C C G+ G C SCP C N G C+ +G C+C
Sbjct: 574 -------VDGQCICHEGFTGLDCGQHSCPS-----------DCNNLGQCV--SGRCICNE 613
Query: 600 GFRGPSCQRSCQP 612
G+ G C P
Sbjct: 614 GYSGEDCSEVSPP 626
Score = 167 bits (423), Expect = 5e-41
Identities = 137/461 (29%), Positives = 177/461 (38%), Gaps = 131/461 (28%)
Query: 91 CHGFYESRGFCVPLCAQECVH-GRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCS 149
CH + PLC C + GRCV N+C C G+ G+DCS P
Sbjct: 270 CHDGFAGDDCNKPLCLNNCYNRGRCVE-NECVCDEGFTGEDCSELICPN----------D 318
Query: 150 CGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPA 209
C + C +G C C G +C +P P AC + +C + G C C
Sbjct: 319 CFDRGRCI--NGTCYCEEGFTGEDCGKPTCPH----ACHTQGRC-------EEGQCVCDE 365
Query: 210 ERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICS-LPCPEGFH 268
G V CS+ CP+ C N G + G C C G+ G C L CP G
Sbjct: 366 GFAG----VDCSEKR----CPA--DCHNRG--RCVDGRCECDDGFTGADCGELKCPNG-- 411
Query: 269 GPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCRE------------------ECPVGR 310
CS RC NG QC C GYTG+ C + C G
Sbjct: 412 ---CSGHGRCVNG--------QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGF 460
Query: 311 FGQDCAE-TC--DCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDR 367
G DC++ +C DC RC NG C+C+ G+TG+ C DR CP C C
Sbjct: 461 KGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRDRQCP-----RDCSNRGLC-- 511
Query: 368 EHSLSCHPMNGECSCLPGWAGLHCNE-SCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCA 426
++G+C C G+ G C E SCP D HG G + +G C C
Sbjct: 512 --------VDGQCVCEDGFTGPDCAELSCPNDCHGQG-------------RCVNGQCVCH 550
Query: 427 PGYTGPHC-ASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV-PCPPG 484
G+ G C CP D +G RC +DG+C+C EG+ +C CP
Sbjct: 551 EGFMGKDCKEQRCPSDCHG---QGRC----------VDGQCICHEGFTGLDCGQHSCPS- 596
Query: 485 TWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCP 525
CN QC +G C C G+ G C P
Sbjct: 597 ----DCNNLGQCV--------SGRCICNEGYSGEDCSEVSP 625
Score = 165 bits (417), Expect = 2e-40
Identities = 137/453 (30%), Positives = 174/453 (38%), Gaps = 137/453 (30%)
Query: 291 CRCAPGYTGDRCRE-ECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRL 349
C C PG+ G C E ECP +C RC +G C+C+ GFTG+ C+
Sbjct: 174 CVCEPGWKGPNCSEPECPG-----------NCHLRGRCI--DGQCICDDGFTGEDCSQLA 220
Query: 350 CPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN-ESCPQDTHGPGCQEHC 408
CP C C +NG C C G+AG C+ E CP P +EH
Sbjct: 221 CPS-----DCNDQGKC----------VNGVCICFEGYAGADCSREICPV----PCSEEHG 261
Query: 409 LCLHGGVCQATSGLCQCAPGYTGPHCAS-LCPPDTYGVNCSARCSCENAIACSPIDGECV 467
C+ GLC C G+ G C LC NC R C ++ ECV
Sbjct: 262 TCV--------DGLCVCHDGFAGDDCNKPLCLN-----NCYNRGRC--------VENECV 300
Query: 468 CKEGWQRGNCS-VPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLP-CP 525
C EG+ +CS + CP C C G C C G+ G C P CP
Sbjct: 301 CDEGFTGEDCSELICPN-----------DCFDRGRCI--NGTCYCEEGFTGEDCGKPTCP 347
Query: 526 KGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKN 584
+G RC+ G+C C G+ G C CP C N
Sbjct: 348 HACHTQG---RCE----------EGQCVCDEGFAGVDCSEKRCP-----------ADCHN 383
Query: 585 GGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWT 644
G C+ +G C C GF G C G+ P C+ H C NG C C G+T
Sbjct: 384 RGRCV--DGRCECDDGFTGADC---------GELKCPNGCSGHGRC--VNGQCVCDEGYT 430
Query: 645 GPDCSQ-PCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLE-GCPLGTFGA 702
G DCSQ CP CH G C +G C+C G+ G+ C + CP
Sbjct: 431 GEDCSQLRCPN-----------DCHSRGRC--VEGKCVCEQGFKGYDCSDMSCP-----N 472
Query: 703 NCSQPCQCGPGEKCHPETGACVCPPGHSGAPCR 735
+C Q +C G CVC G++G CR
Sbjct: 473 DCHQHGRC--------VNGMCVCDDGYTGEDCR 497
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 213 bits (543), Expect = 6e-55
Identities = 198/707 (28%), Positives = 263/707 (37%), Gaps = 158/707 (22%)
Query: 104 LCAQECV--HGRCVAPNQCQCVPGWRGDDCSSECAP--GMWGPQCDKPCSCGNNSSCDPK 159
+C Q C HG C P C+C GW+G C +C P G C++P C C+
Sbjct: 233 ICRQGCSPKHGSCKLPGDCRCQYGWQGLYCD-KCIPHPGCVHGICNEPWQC----LCETN 287
Query: 160 SGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVS 219
G C L QPC G C G P C CP +GP+C+++
Sbjct: 288 WGGQLCDKDLNYCGTHQPCLNGG-------TCSNTG----PDKYQCSCPEGYSGPNCEIA 336
Query: 220 CSQGTSGFFCPSTHSCQNGGVFQTPQG-SCSCPPGWMGTICSLPCPEGFHGPNCSQECRC 278
C S G +T G C C PGW G CS + CS C
Sbjct: 337 ------EHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDD------CSPN-NC 383
Query: 279 HNGGLCDRFTG--QCRCAPGYTGDRCREECPVGRFGQDC-AETCDCAPDARCFPANGACL 335
+GG C +C C P +TG C+ + +C A+ C A + A+ C
Sbjct: 384 SHGGTCQDLVNGFKCVCPPQWTGKTCQLDA------NECEAKPCVNAKSCKNLIASYYCD 437
Query: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPM-NG-ECSCLPGWAGLHCN- 392
C G+ G C + C C ++ SC + NG C C PG+AG HC
Sbjct: 438 CLPGWMGQNCDININ-------DCLGQC----QNDASCRDLVNGYRCICPPGYAGDHCER 486
Query: 393 --ESCPQDT--HGPGCQEH-----CLC---LHGGVCQATSGLCQCAPGYTGPHCASL--- 437
+ C + +G CQ CLC G +CQ C+ P G C +
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASD 546
Query: 438 ----CPPDTYGVNCSA---RC---------SCENAIA---------------CSPIDGEC 466
CP D G NCS C SC A+A C P G+C
Sbjct: 547 YFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGP-HGKC 605
Query: 467 VCKEGWQRGNCSVPCPPGTWGFSCNAS---CQ---CAHEAVCSPQTGA--CTCTPGWHGA 518
+ G G + C G G C+ + C+ C + C + C C+ GW GA
Sbjct: 606 KSQSG---GKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGA 662
Query: 519 HCQLPCPKGQFGEGCASRCDCDHSDGC-DPVHG-RCQCQAGWMGARCHLSCPEGLWGVNC 576
+C+ S+ C + C D V+ C C+ GW G CH +
Sbjct: 663 YCETNIND-------CSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ------- 708
Query: 577 SNTCTCKNGGTCLPENG--NCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HP 632
+ TC NGGTC E C+C G+ G +C + C+P C N C +
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-----RNSSCLPNPCHNGGTCVVNG 763
Query: 633 SNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDG--SCICPLGWTGHH 690
+ TC C GW GP C+Q N C++ GTC D C C G+ G
Sbjct: 764 ESFTCVCKEGWEGPICAQ-------NTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPD 816
Query: 691 CLEGCPLGTFGANCSQPCQCGPGEKCHPETGA--CVCPPGHSGAPCR 735
C N Q C G C E CVCPPGHSGA C+
Sbjct: 817 C-------RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Score = 200 bits (509), Expect = 5e-51
Identities = 202/786 (25%), Positives = 272/786 (34%), Gaps = 194/786 (24%)
Query: 52 SEPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQC-----CHGFYESRGFCVPLCA 106
++ C W GP R + RQ H C C Y +G C
Sbjct: 217 NKTCMEGWMGPEC-------NRAICRQGCSPKHGS---CKLPGDCRCQYGWQGLYCDKCI 266
Query: 107 QE--CVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCD---PKSG 161
CVHG C P QC C W G C + C C N +C P
Sbjct: 267 PHPGCVHGICNEPWQCLCETNWGGQLCDKDL------NYCGTHQPCLNGGTCSNTGPDKY 320
Query: 162 VCSCPSGLQPPNC--------LQP-----------------CTPGYYGPACQFRCQ---- 192
CSCP G PNC P C+PG+ GP C
Sbjct: 321 QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSP 380
Query: 193 ---CHGAPCDPQTGA--CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS 247
HG C C CP + TG +C + ++ C + SC+N
Sbjct: 381 NNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSCKN----LIASYY 435
Query: 248 CSCPPGWMGTICSLPCPEGFHGPNCSQEC--RCHNGGLC-DRFTG-QCRCAPGYTGDRCR 303
C C PGWMG C + +C +C N C D G +C C PGY GD C
Sbjct: 436 CDCLPGWMGQNCDINI----------NDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCE 485
Query: 304 ---EECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTG-------DRCTDRLCPDG 353
+EC C C + F CLC GF+G D C C +G
Sbjct: 486 RDIDECA----SNPCLNGGHCQNEINRF----QCLCPTGFSGNLCQLDIDYCEPNPCQNG 537
Query: 354 --FYGLSCQAPCTCDREH-SLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQ--EHC 408
Y + C C ++ +C + C P C + + G +
Sbjct: 538 AQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSN 597
Query: 409 LCLHGGVCQATSG---LCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG- 464
+C G C++ SG C C G+TG +C +N C N C IDG
Sbjct: 598 VCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE-------NINDCESNPCRNGGTC--IDGV 648
Query: 465 ---ECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTG--ACTCTPGWHGAH 519
+C+C +GW+ C C+ + C + C C C GW G
Sbjct: 649 NSYKCICSDGWEGAYCETNIN------DCSQN-PCHNGGTCRDLVNDFYCDCKNGWKGKT 701
Query: 520 CQLPCPKGQFGEGCASRCD---CDHSDGC--DPVHGRCQCQAGWMGARCHLSCPEGLWGV 574
C S+CD C++ C + +C C GW G C+++
Sbjct: 702 C----------HSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA-------- 743
Query: 575 NCSNTC---TCKNGGTCL--PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSF 629
+++C C NGGTC+ E+ CVC G+ GP C ++ C P C N
Sbjct: 744 -RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND------CSPHPCYNSGT 796
Query: 630 CHPSNG--TCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS--CICPLG 685
C + C C G+ GPDC N Q+ C G TC + C+CP G
Sbjct: 797 CVDGDNWYRCECAPGFAGPDC-------RININECQSSPCAFGATCVDEINGYRCVCPPG 849
Query: 686 WTGHHCLE--GCPLGTFGA----------NCSQPCQCGPGE------KCHPETGACVCPP 727
+G C E G P T G+ +C+ CQC G C P C+
Sbjct: 850 HSGAKCQEVSGRPCITMGSVIPDGAKWDDDCN-TCQCLNGRIACSKVWCGPR--PCLLHK 906
Query: 728 GHSGAP 733
GHS P
Sbjct: 907 GHSECP 912
Score = 115 bits (288), Expect = 2e-25
Identities = 95/338 (28%), Positives = 115/338 (34%), Gaps = 108/338 (31%)
Query: 479 VPCPPGTWGFSCNASCQCAHEAV---CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCAS 535
V C +GF CN C+ + Q G TC GW G C +
Sbjct: 185 VTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPEC--------------N 230
Query: 536 RCDCDHSDGCDPVHGRCQ------CQAGWMGARC-----HLSCPEGL------------W 572
R C GC P HG C+ CQ GW G C H C G+ W
Sbjct: 231 RAIC--RQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNW 288
Query: 573 GVN--------CSNTCTCKNGGTCL---PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVP 621
G C C NGGTC P+ C C G+ GP+C+ + C+
Sbjct: 289 GGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIA------EHACLS 342
Query: 622 CKCANHSFCHPSN--GTCYCLAGWTGPDCS---QPCPPGHWGENCAQTCQCHHGGTCHP- 675
C N C ++ C C GWTGP CS C P + C HGGTC
Sbjct: 343 DPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN----------CSHGGTCQDL 392
Query: 676 -QDGSCICPLGWTGHHC-LEG------------------------CPLGTFGANCS---Q 706
C+CP WTG C L+ C G G NC
Sbjct: 393 VNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININ 452
Query: 707 PC--QCGPGEKCHPETGA--CVCPPGHSGAPCRIGIQE 740
C QC C C+CPPG++G C I E
Sbjct: 453 DCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDE 490
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 209 bits (533), Expect = 8e-54
Identities = 209/768 (27%), Positives = 266/768 (34%), Gaps = 204/768 (26%)
Query: 101 CVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSE-------------------------- 134
CVP CVHG CV P QC C W G C +
Sbjct: 276 CVPYPG--CVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRC 333
Query: 135 -CAPGMWGPQCDK---PCS---CGNNSSCD--PKSGVCSCPSGLQPPNCLQPCTPGYYGP 185
C G G C+K C+ C N SC P C CPSG P C P
Sbjct: 334 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNP 393
Query: 186 ACQFRCQCHGAPCDPQTG-ACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQN--GGVFQ 242
C G D G C CP + G +C + ++ G C + SC+N GG +
Sbjct: 394 -----CAAGGTCVDQVDGFECICPEQWVGATCQLDANE-CEGKPCLNAFSCKNLIGGYY- 446
Query: 243 TPQGSCSCPPGWMGTICSL------------------------PCPEGFHGPNCS---QE 275
C C PGW G C + CP GF G +C E
Sbjct: 447 -----CDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDE 501
Query: 276 CR---CHNGGLCDRFTG--QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPA 330
C CH+GGLC+ C C G++G C + D E C ARC+
Sbjct: 502 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDV-------DLCEPSPCRNGARCYNL 554
Query: 331 NG--ACLCEHGFTGDRCT--DRLCPDGFYGLSCQAPCTCDRE---------HSLSCHPM- 376
G C C F G C+ CP G +C+ C + S C P
Sbjct: 555 EGDYYCACPDDFGGKNCSVPREPCPGG----ACRVIDGCGSDAGPGMPGTAASGVCGPHG 610
Query: 377 --------NGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVC--QATSGLCQCA 426
N C C G+ G +C+E+ P C +GG C + + C C
Sbjct: 611 RCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQP-------CRNGGTCIDEVDAFRCFCP 663
Query: 427 PGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTW 486
G+ G C P D C +R C + + D C C +GW+ C +
Sbjct: 664 SGWEGELC-DTNPNDCLPDPCHSRGRCYDLVN----DFYCACDDGWKGKTCH------SR 712
Query: 487 GFSCNASCQCAHEAVC--SPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDG 544
F C+A C++ C S T C C PGW G+ C + C + C S
Sbjct: 713 EFQCDA-YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG- 770
Query: 545 CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENG--NCVCAPGFR 602
C C+ GW G C N N C NGG C+ C CAPGF
Sbjct: 771 ---ASFSCICRDGWEGRTC-------THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFA 820
Query: 603 GPSCQ---RSCQ--PGRYGKRCVPCKCANHSFCHPSNG-TCYCLAGWTGPDCSQ------ 650
GP C+ CQ P YG CV NG C C G GP C +
Sbjct: 821 GPDCRINIDECQSSPCAYGATCV----------DEINGYRCSCPPGRAGPRCQEVIGFGR 870
Query: 651 -------PCPPG-HWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGA 702
P P G W E+C +C+C DG C W G P G
Sbjct: 871 SCWSRGTPFPHGSSWVEDC-NSCRC--------LDGRRDCSKVWCGWK-----PCLLAGQ 916
Query: 703 NCSQPCQCGPGEKC-HPETGACVCPPGHSGAPCRIGIQEPFTVMPTTP 749
+ QC G++C G C+ PP + C G +EP P+TP
Sbjct: 917 PEALSAQCPLGQRCLEKAPGQCLRPPCEAWGEC--GAEEP----PSTP 958
Score = 186 bits (472), Expect = 1e-46
Identities = 207/764 (27%), Positives = 262/764 (34%), Gaps = 210/764 (27%)
Query: 87 RLQCCHGFYES--RGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQC 144
R++C +Y + FC P H C C+ GW G +C C
Sbjct: 195 RVRCDENYYSATCNKFCRPR-NDFFGHYTCDQYGNKACMDGWMGKECKEAV--------C 245
Query: 145 DKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA 204
+ C+ + P G C C G Q C C P P C HG+ +P
Sbjct: 246 KQGCNLLHGGCTVP--GECRCSYGWQGRFC-DECVP---YPGC-----VHGSCVEP--WQ 292
Query: 205 CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGV---FQTPQGSCSCPPGWMGTIC-- 259
C C G CD + +C S H C NGG + Q C+CP G+ G C
Sbjct: 293 CNCETNWGGLLCDKDLN------YCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK 346
Query: 260 -----------------------SLPCPEGFHGPNCS---QECR---CHNGGLC-DRFTG 289
CP G+ GP C+ EC C GG C D+ G
Sbjct: 347 AEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDG 406
Query: 290 -QCRCAPGYTGDRCR---EECPVGRFGQDCAET-----------CDCAP---DARCFPAN 331
+C C + G C+ EC G+ C CDC P C
Sbjct: 407 FECICPEQWVGATCQLDANECE----GKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINV 462
Query: 332 GAC--LCEHGFT------GDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCL 383
C C+HG T G +C +CP GF G C+ D S CH G C L
Sbjct: 463 NDCRGQCQHGGTCKDLVNGYQC---VCPRGFGGRHCE--LERDECASSPCH-SGGLCEDL 516
Query: 384 PGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL------ 437
G HC+ CPQ GP +C+ LC+ +P G C +L
Sbjct: 517 AD--GFHCH--CPQGFSGP------------LCEVDVDLCEPSPCRNGARCYNLEGDYYC 560
Query: 438 -CPPDTYGVNCSA-RCSCENAIACSPID----------------------GECVCKEGWQ 473
CP D G NCS R C AC ID G CV + G
Sbjct: 561 ACPDDFGGKNCSVPREPCPGG-ACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG-- 617
Query: 474 RGNCSVPCPPGTWGFSCNASCQ------CAHEAVCSPQTGA--CTCTPGWHGAHCQLPCP 525
GN S C G G C+ + C + C + A C C GW G C P
Sbjct: 618 -GNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTN-P 675
Query: 526 KGQFGEGCASRCDCDHSDGCDPVHG-RCQCQAGWMGARCH---LSCPEGLWGVNCSNTCT 581
+ C SR C D V+ C C GW G CH C + T
Sbjct: 676 NDCLPDPCHSRGRC-----YDLVNDFYCACDDGWKGKTCHSREFQC----------DAYT 720
Query: 582 CKNGGTCLP--ENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNG--TC 637
C NGGTC + C C PG++G +C + C+P C N C S +C
Sbjct: 721 CSNGGTCYDSGDTFRCACPPGWKGSTCAVA-----KNSSCLPNPCVNGGTCVGSGASFSC 775
Query: 638 YCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDG----SCICPLGWTGHHCLE 693
C GW G C+ N C++GG C DG C C G+ G C
Sbjct: 776 ICRDGWEGRTCTH-------NTNDCNPLPCYNGGIC--VDGVNWFRCECAPGFAGPDC-- 824
Query: 694 GCPLGTFGANCSQPCQCGPGEKCHPETGA--CVCPPGHSGAPCR 735
+ Q C G C E C CPPG +G C+
Sbjct: 825 -----RINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 863
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 209 bits (532), Expect = 1e-53
Identities = 203/738 (27%), Positives = 261/738 (35%), Gaps = 182/738 (24%)
Query: 101 CVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSC---D 157
CVP CVHG CV P QC C W G C + C C N +C +
Sbjct: 276 CVPYPG--CVHGSCVEPWQCNCETNWGGLLCDKDL------NYCGSHHPCTNGGTCINAE 327
Query: 158 PKSGVCSCPSGLQPPNCLQ---PCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGP 214
P C+CP G NC + CT C CH P + C CP+ +GP
Sbjct: 328 PDQYRCTCPDGYSGRNCEKAEHACTSN----PCANGGSCHEVPSGFE---CHCPSGWSGP 380
Query: 215 SCDVSCSQGTSGFFCPSTHSCQNGG--VFQTPQGSCSCPPGWMGTICSLP---------- 262
+C + + S + C GG V Q C CP W+G C L
Sbjct: 381 TCALDIDECAS-------NPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQH 433
Query: 263 --------------CPEGFHGPNCS---QECR---CHNGGLCDRFTG--QCRCAPGYTGD 300
CP GF G +C EC CH+GGLC+ C C G++G
Sbjct: 434 GGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGP 493
Query: 301 RCREECPVGRFGQDCAETCDCAPDARCFPANG--ACLCEHGFTGDRCT--DRLCPDGFYG 356
C + D E C ARC+ G C C F G C+ CP G
Sbjct: 494 LCEVDV-------DLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGG--- 543
Query: 357 LSCQAPCTCDRE---------HSLSCHPM---------NGECSCLPGWAGLHCNESCPQD 398
+C+ C + S C P N C C G+ G +C+E+
Sbjct: 544 -ACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 602
Query: 399 THGPGCQEHCLCLHGGVC--QATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENA 456
P C +GG C + + C C G+ G C P D C +R C +
Sbjct: 603 LGQP-------CRNGGTCIDEVDAFRCFCPSGWEGELC-DTNPNDCLPDPCHSRGRCYDL 654
Query: 457 IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVC--SPQTGACTCTPG 514
+ D C C +GW+ C + F C+A C++ C S T C C PG
Sbjct: 655 VN----DFYCACDDGWKGKTCH------SREFQCDA-YTCSNGGTCYDSGDTFRCACPPG 703
Query: 515 WHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGV 574
W G+ C + C + C S C C+ GW G C
Sbjct: 704 WKGSTCAVAKNSSCLPNPCVNGGTCVGSG----ASFSCICRDGWEGRTC-------THNT 752
Query: 575 NCSNTCTCKNGGTCLPENG--NCVCAPGFRGPSCQ---RSCQ--PGRYGKRCVPCKCANH 627
N N C NGG C+ C CAPGF GP C+ CQ P YG CV
Sbjct: 753 NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCV------- 805
Query: 628 SFCHPSNG-TCYCLAGWTGPDCSQ-------------PCPPG-HWGENCAQTCQCHHGGT 672
NG C C G GP C + P P G W E+C +C+C
Sbjct: 806 ---DEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDC-NSCRC----- 856
Query: 673 CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKC-HPETGACVCPPGHSG 731
DG C W G P G + QC G++C G C+ PP +
Sbjct: 857 ---LDGRRDCSKVWCGWK-----PCLLAGQPEALSAQCPLGQRCLEKAPGQCLRPPCEAW 908
Query: 732 APCRIGIQEPFTVMPTTP 749
C G +EP P+TP
Sbjct: 909 GEC--GAEEP----PSTP 920
Score = 131 bits (330), Expect = 3e-30
Identities = 134/486 (27%), Positives = 172/486 (35%), Gaps = 151/486 (31%)
Query: 350 CPDGFYGLSCQAPC----------TCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDT 399
C + +Y +C C TCD+ G +C+ GW G C E+
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQY---------GNKACMDGWMGKECKEAV---- 244
Query: 400 HGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCP-PDTYGVNCSA--RCSCE-- 454
C++ C LHGG G C+C+ G+ G C P P +C +C+CE
Sbjct: 245 ----CKQGCNLLHGGC--TVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETN 298
Query: 455 -----------------------NAIACSPIDGECVCKEGWQRGNC--------SVPCPP 483
I P C C +G+ NC S PC
Sbjct: 299 WGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCAN 358
Query: 484 G------TWGFSCN-----------------ASCQCAHEAVCSPQTGA--CTCTPGWHGA 518
G GF C+ AS CA C Q C C W GA
Sbjct: 359 GGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGA 418
Query: 519 HCQLPCPKGQFGEGCASRCDCDHSDGC-DPVHG-RCQCQAGWMGARCHLSCPEGLWGVNC 576
CQL C R C H C D V+G +C C G+ G C L E C
Sbjct: 419 TCQLDV------NDC--RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDE------C 464
Query: 577 SNTCTCKNGGTC--LPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSN 634
+++ C +GG C L + +C C GF GP C+ C P C N + C+
Sbjct: 465 ASS-PCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVD------LCEPSPCRNGARCYNLE 517
Query: 635 GTCYCLA--GWTGPDCS---QPCP---------------PGHWGENCAQTCQCHHGGTCH 674
G YC + G +CS +PCP PG G + C H G C
Sbjct: 518 GDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPH--GRCV 575
Query: 675 PQDG---SCICPLGWTGHHCLEGCPLGTFGANC-SQPCQCGPGEKCHPETGA--CVCPPG 728
Q G SCIC G+TG +C E +C QPC+ G C E A C CP G
Sbjct: 576 SQPGGNFSCICDSGFTGTYCHENID------DCLGQPCR--NGGTCIDEVDAFRCFCPSG 627
Query: 729 HSGAPC 734
G C
Sbjct: 628 WEGELC 633
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 204 bits (519), Expect = 3e-52
Identities = 169/576 (29%), Positives = 211/576 (36%), Gaps = 126/576 (21%)
Query: 190 RCQCHGA--------PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPST----HSCQN 237
RC CHG P DP C C G +CD C + P+T + CQ+
Sbjct: 299 RCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
Query: 238 -------------------------GGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPN- 271
G +Q C G C P + PN
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
Query: 272 ------CSQECRCHNG---GLCDRFTGQCRCAPGYTGDRCREECPVGRFG-QDCAET--- 318
+ C C + G C+ TG+C C P ++G+RC + C G G C T
Sbjct: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC-DVCAEGFTGFPSCYPTPSS 477
Query: 319 ----------------CDCAPDA------RCFPANGACLCEHGFTGDRCTDRLCPDGFYG 356
CDC+ R P G CLC+ F G C LC GFYG
Sbjct: 478 SNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHC--ELCAPGFYG 535
Query: 357 LSCQAPCTCDREHSLS--CHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGG 414
CQ PC C C P G+C C G+ G C+ P H P CQ C C G
Sbjct: 536 PGCQ-PCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQL-CGCSPAG 593
Query: 415 VCQA---TSGLCQCAPGYTGPHCASLCPPDTYGV-NCSARCSCENAIACSPIDGE---CV 467
+G C C P + GPHC C P +G NC A C+C+ A + G C
Sbjct: 594 TLPEGCDEAGRCLCQPEFAGPHC-DRCRPGYHGFPNCQA-CTCDPRGALDQLCGAGGLCR 651
Query: 468 CKEGWQRGNCSVPCPPGTWGFSCNASCQCAHE----AVCSPQTGACTCTPGWHGAHCQLP 523
C+ G+ C C PG GF C C+ E A C P++G C+C P G C
Sbjct: 652 CRPGYTGTACQ-ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT- 709
Query: 524 CPKGQFGEGCASRCDCDHSDGCDPVHGR-------CQCQAGWMGARCHLSCPEGLWGVNC 576
C G + C H G PV C C+A G C C G WG++
Sbjct: 710 CVPGAYNFPYCEAGSC-HPAGLAPVDPALPEAQVPCMCRAHVEGPSCD-RCKPGFWGLSP 767
Query: 577 SNT-----CTCKNGGT------CLPENGNCVCAPGFRGPSCQRSCQPGRYGKR------C 619
SN C+C GT C P G C C P G +C SC+ G +G C
Sbjct: 768 SNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQADYFGC 826
Query: 620 VPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQP 651
C+C A C P G C C GP CS+P
Sbjct: 827 RSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEP 862
Score = 182 bits (462), Expect = 1e-45
Identities = 162/555 (29%), Positives = 202/555 (36%), Gaps = 163/555 (29%)
Query: 119 QCQCVPGWRGDDCSSECAPGM----WGP-------QCDKPCSC-GNNSSC--DPK----- 159
QC C G C C PG W P +C C+C G+ + C DP+
Sbjct: 321 QCTCQHNTCGGTCD-RCCPGFNQQPWKPATANSANECQS-CNCYGHATDCYYDPEVDRRR 378
Query: 160 -----------SGVC-SCPSGLQPPNCLQPCTPGYY--------GPACQFRCQCHG---- 195
GVC C NC + C PG+Y P RC C
Sbjct: 379 ASQSLDGTYQGGGVCIDCQHHTTGVNC-ERCLPGFYRSPNHPLDSPHVCRRCNCESDFTD 437
Query: 196 APCDPQTGACFCPAERTGPSCDVSCSQGTSGF-FCPSTHSCQNGGVFQT----------- 243
C+ TG C+C +G CDV C++G +GF C T S N Q
Sbjct: 438 GTCEDLTGRCYCRPNFSGERCDV-CAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDC 496
Query: 244 -------------PQ-GSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGL----CD 285
P+ G C C P + GT C L C GF+GP C Q C+C + G+ CD
Sbjct: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFYGPGC-QPCQCSSPGVADDRCD 554
Query: 286 RFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDA-------------------- 325
TGQCRC G+ G C + C G F + C C+P
Sbjct: 555 PDTGQCRCRVGFEGATC-DRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAG 613
Query: 326 ----RCFP------------------------ANGACLCEHGFTGDRCTDRLCPDGFYGL 357
RC P A G C C G+TG C + C GF+G
Sbjct: 614 PHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQE--CSPGFHGF 671
Query: 358 SCQAPCTCDREHSL--SCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGV 415
PC C E SL +C P +G+CSC P GL C+ P + P C E C G+
Sbjct: 672 PSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC-EAGSCHPAGL 730
Query: 416 CQATSGL------CQCAPGYTGPHCASLCPPDTYGVNCS-----ARCSCE------NAIA 458
L C C GP C C P +G++ S RCSC+
Sbjct: 731 APVDPALPEAQVPCMCRAHVEGPSC-DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAE 789
Query: 459 CSPIDGECVCKEGWQRGNCSVPCPPGTWG------FSCNASCQC----AHEAVCSPQTGA 508
C P G+C CK G C G +G F C SC+C A C P+TG
Sbjct: 790 CQPGTGQCFCKP-HVCGQACASCKDGFFGLDQADYFGCR-SCRCDIGGALGQSCEPRTGV 847
Query: 509 CTCTPGWHGAHCQLP 523
C C P G C P
Sbjct: 848 CRCRPNTQGPTCSEP 862
Score = 159 bits (403), Expect = 1e-38
Identities = 137/478 (28%), Positives = 178/478 (37%), Gaps = 87/478 (18%)
Query: 316 AETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREH---SLS 372
A+ CD F C C+H G C DR CP + P T + + S +
Sbjct: 306 ADACDAKDPTDPFRLQ--CTCQHNTCGGTC-DRCCPG--FNQQPWKPATANSANECQSCN 360
Query: 373 CHPMNGECSCLPGWAGLHCNESCPQDTHGPG----CQEHCLCLHGGVCQATSGLCQCAPG 428
C+ +C P ++S G G CQ H G C+ +C PG
Sbjct: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTT---GVNCE------RCLPG 411
Query: 429 YTGPHCASLCPPDTYGVNCSARCSCENAIA---CSPIDGECVCKEGWQRGNCSVPCPPGT 485
+ L P + RC+CE+ C + G C C+ + C V C G
Sbjct: 412 FYRSPNHPLDSP-----HVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAEGF 465
Query: 486 WGF------------------------SCNASCQCAHEAVC--SPQTGACTCTPGWHGAH 519
GF +C+ S C P+ G C C P + G H
Sbjct: 466 TGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTH 525
Query: 520 CQLPCPKGQFGEGCASRCDCDH----SDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVN 575
C+L C G +G GC C C D CDP G+C+C+ G+ GA C C G +
Sbjct: 526 CEL-CAPGFYGPGCQP-CQCSSPGVADDRCDPDTGQCRCRVGFEGATCD-RCAPGYFHFP 582
Query: 576 CSNTCTCKNGGTCLPEN----GNCVCAPGFRGPSCQRSCQPGRYG-KRCVPCKC----AN 626
C C GT LPE G C+C P F GP C R C+PG +G C C C A
Sbjct: 583 LCQLCGCSPAGT-LPEGCDEAGRCLCQPEFAGPHCDR-CRPGYHGFPNCQACTCDPRGAL 640
Query: 627 HSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT----CHPQDGSCIC 682
C + G C C G+TG C Q C PG G C C G+ C P+ G C C
Sbjct: 641 DQLC-GAGGLCRCRPGYTGTAC-QECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSC 698
Query: 683 PLGWTGHHCLEGCPLGTFG-----ANCSQPCQCGPGEKCHPETGA-CVCPPGHSGAPC 734
TG C + C G + A P P + PE C+C G C
Sbjct: 699 RPRVTGLRC-DTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC 755
Score = 145 bits (366), Expect = 2e-34
Identities = 114/350 (32%), Positives = 143/350 (40%), Gaps = 73/350 (20%)
Query: 120 CQCVPGWRGDDCSSECAPGMWGP-------QCDKPCSC-GNNSSCDPKSGVC-SCPSGLQ 170
C C +RGD C ECAPG + +C PC C G++ C P SGVC C +
Sbjct: 1831 CLCPASYRGDSC-QECAPGFYRDVKGLFLGRC-VPCQCHGHSDRCLPGSGVCVDCQHNTE 1888
Query: 171 PPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP 230
+C + C G+ + DP CP + PS
Sbjct: 1889 GAHC-ERCQAGFV-----------SSRDDPSAPCVSCPCPLSVPS--------------- 1921
Query: 231 STHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP----NCSQECRCHNGG---- 282
++ G V + + C C PG+ G C P F P + Q C C G
Sbjct: 1922 --NNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNL 1979
Query: 283 ---LCDRFTGQCR-CAPGYTGDRCREECPVGRFGQ-----DCAETCDCAP--DARCFPAN 331
CD TG CR C TG RC E C G +G +C CDC P C P +
Sbjct: 1980 LFSDCDPLTGACRGCLRHTTGPRC-EICAPGFYGNALLPGNCTR-CDCTPCGTEACDPHS 2037
Query: 332 GACLCEHGFTGDRCTDRLCPDGFYGL----SCQAPCTC-DREHSLSCHPMNGECSCLPGW 386
G CLC+ G TG RC DR C +G +G C+ PC C CHP +G+C C PG
Sbjct: 2038 GHCLCKAGVTGRRC-DR-CQEGHFGFDGCGGCR-PCACGPAAEGSECHPQSGQCHCRPGT 2094
Query: 387 AGLHCNESCPQDTHGP--GCQEHCLCLHGGVCQATSGLCQCAPGYTGPHC 434
G C E P P GC+ C C GG C +G C C PG +G C
Sbjct: 2095 MGPQCRECAPGYWGLPEQGCR-RCQC-PGGRCDPHTGRCNCPPGLSGERC 2142
Score = 143 bits (361), Expect = 7e-34
Identities = 106/329 (32%), Positives = 132/329 (40%), Gaps = 59/329 (17%)
Query: 414 GVCQATSGLCQCAPGYTGPHCASLCPPDTYG------VNCSARCSCE-NAIACSPIDGEC 466
G + LC C Y G C C P Y + C C ++ C P G C
Sbjct: 1822 GALASNVELCLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVC 1880
Query: 467 V-CKEGWQRGNCSVPCPPGTWGFSCNASCQC--------------AHEAVCSPQTGACTC 511
V C+ + +C C G + S C A V C C
Sbjct: 1881 VDCQHNTEGAHCE-RCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLC 1939
Query: 512 TPGWHGAHCQLPCPKGQFGE-----GCASRCDCDHS-------DGCDPVHGRCQ-CQAGW 558
PG+ GA C+ C G FG CDC + CDP+ G C+ C
Sbjct: 1940 KPGYAGASCE-RCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHT 1998
Query: 559 MGARCHLSCPEGLWG-----VNCSNTCTCKNGGT--CLPENGNCVCAPGFRGPSCQRSCQ 611
G RC + C G +G NC+ C C GT C P +G+C+C G G C R CQ
Sbjct: 1999 TGPRCEI-CAPGFYGNALLPGNCTR-CDCTPCGTEACDPHSGHCLCKAGVTGRRCDR-CQ 2055
Query: 612 PGRYG----KRCVPCKC---ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWG--ENCA 662
G +G C PC C A S CHP +G C+C G GP C + C PG+WG E
Sbjct: 2056 EGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQGC 2114
Query: 663 QTCQCHHGGTCHPQDGSCICPLGWTGHHC 691
+ CQC GG C P G C CP G +G C
Sbjct: 2115 RRCQC-PGGRCDPHTGRCNCPPGLSGERC 2142
Score = 129 bits (324), Expect = 1e-29
Identities = 111/418 (26%), Positives = 154/418 (36%), Gaps = 95/418 (22%)
Query: 369 HSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLH---GGVCQATSGLCQC 425
+S+ + G C C G A C+ P D + C C H GG C +C
Sbjct: 289 YSIKDISIGGRCVC-HGHADA-CDAKDPTDPF----RLQCTCQHNTCGGTCD------RC 336
Query: 426 APGY-----------TGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQR 474
PG+ + C S C + +C + A +DG +Q
Sbjct: 337 CPGFNQQPWKPATANSANECQS-CNCYGHATDCYYDPEVDRRRASQSLDGT------YQG 389
Query: 475 GNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCA 534
G + C T G +C C PG++ + P C
Sbjct: 390 GGVCIDCQHHTTGVNCER------------------CLPGFYRSPNH-PLDSPHVCRRC- 429
Query: 535 SRCDCDHSDG-CDPVHGRCQCQAGWMGARCHLSCPEGLWG-------------------- 573
C+ D +DG C+ + GRC C+ + G RC + C EG G
Sbjct: 430 -NCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAEGFTGFPSCYPTPSSSNDTREQVLP 487
Query: 574 ----VNCSNTCTCKNGGTCL--PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANH 627
VNC + G C P G C+C P F+G C+ C PG YG C PC+C++
Sbjct: 488 AGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFYGPGCQPCQCSSP 546
Query: 628 SF----CHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHP---QDGSC 680
C P G C C G+ G C + C PG++ Q C C GT + G C
Sbjct: 547 GVADDRCDPDTGQCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRC 605
Query: 681 ICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGA---CVCPPGHSGAPCR 735
+C + G HC + C G G Q C C P GA C C PG++G C+
Sbjct: 606 LCQPEFAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ 662
Score = 121 bits (304), Expect = 3e-27
Identities = 80/214 (37%), Positives = 96/214 (44%), Gaps = 37/214 (17%)
Query: 119 QCQCVPGWRGDDCSSECAPGMWG------PQCDKPCSCGNN-------SSCDPKSGVC-S 164
QC C PG+ G C CAPG +G C +PC C N S CDP +G C
Sbjct: 1936 QCLCKPGYAGASCE-RCAPGFFGNPLVLGSSC-QPCDCSGNGDPNLLFSDCDPLTGACRG 1993
Query: 165 CPSGLQPPNCLQPCTPGYYG----PACQFRCQCHGA---PCDPQTGACFCPAERTGPSCD 217
C P C + C PG+YG P RC C CDP +G C C A TG CD
Sbjct: 1994 CLRHTTGPRC-EICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCD 2052
Query: 218 VSCSQGTSGFF-CPSTHSCQNGGVFQTPQ-----GSCSCPPGWMGTICSLPCPEGFHG-- 269
C +G GF C C G + + G C C PG MG C C G+ G
Sbjct: 2053 -RCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR-ECAPGYWGLP 2110
Query: 270 -PNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRC 302
C + C+C GG CD TG+C C PG +G+RC
Sbjct: 2111 EQGC-RRCQCP-GGRCDPHTGRCNCPPGLSGERC 2142
Score = 112 bits (281), Expect = 1e-24
Identities = 114/386 (29%), Positives = 142/386 (36%), Gaps = 122/386 (31%)
Query: 89 QCCHGFYESRGFCVPLCAQECVHGRCVAPNQC-----QCVPGWRGDDCSSECAPGMWGPQ 143
+C GFY + GRCV P QC +C+PG +C G
Sbjct: 1844 ECAPGFYRD--------VKGLFLGRCV-PCQCHGHSDRCLPG---SGVCVDCQHNTEGAH 1891
Query: 144 CDKPCSCGNNSSCD-PKSGVCSCPSGLQPPN---------------CLQPCTPGYYGPAC 187
C++ C G SS D P + SCP L P+ CL C PGY G +C
Sbjct: 1892 CER-CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL--CKPGYAGASC 1948
Query: 188 Q-----------------FRCQCHG--------APCDPQTGAC-FCPAERTGPSCDVSCS 221
+ C C G + CDP TGAC C TGP C++
Sbjct: 1949 ERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI--- 2005
Query: 222 QGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNG 281
C PG+ G LP NC++ C C
Sbjct: 2006 ----------------------------CAPGFYGN-ALLP-------GNCTR-CDCTPC 2028
Query: 282 G--LCDRFTGQCRCAPGYTGDRCREECPVGRFGQD-C--AETCDCAPDA---RCFPANGA 333
G CD +G C C G TG RC + C G FG D C C C P A C P +G
Sbjct: 2029 GTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQ 2087
Query: 334 CLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNE 393
C C G G +C R C G++GL Q C C P G C+C PG +G C +
Sbjct: 2088 CHCRPGTMGPQC--RECAPGYWGLPEQGCRRCQCPGG-RCDPHTGRCNCPPGLSGERC-D 2143
Query: 394 SCPQDTHGP------GCQEHC-LCLH 412
+C Q P G HC +C H
Sbjct: 2144 TCSQQHQVPVPGGPVGHSIHCEVCDH 2169
Score = 103 bits (256), Expect = 1e-21
Identities = 68/204 (33%), Positives = 87/204 (42%), Gaps = 31/204 (15%)
Query: 146 KPCSC----GNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYG-PACQFRCQCHGAPCDP 200
+PC C +C+P G C C + + +C + C GY+G P C+ C C CD
Sbjct: 1436 RPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCR-PCDCGARLCDE 1493
Query: 201 QTGACFCPAERTGPSCDVSCSQGTSGFF----CPSTHSCQNGGVFQ-------TPQGSCS 249
TG C CP P C + C T G C +C G+ + T G C
Sbjct: 1494 LTGQCICPPRTIPPDC-LLCQPQTFGCHPLVGCEEC-NCSGPGIQELTDPTCDTDSGQCK 1551
Query: 250 CPPGWMGTICSLPCPEGFHG-PNCSQECRCHNG----GLCDRFTGQCRCAPGYTGDRCRE 304
C P G C C GFHG P C + C CH G+CD TGQC C G +C +
Sbjct: 1552 CRPNVTGRRCD-TCSPGFHGYPRC-RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-D 1608
Query: 305 ECPVGRFGQDCAETCDCAPDARCF 328
+C +G F D A C RCF
Sbjct: 1609 QCSLGTFSLDAANPKGC---TRCF 1629
Score = 95.1 bits (235), Expect = 3e-19
Identities = 66/209 (31%), Positives = 78/209 (37%), Gaps = 32/209 (15%)
Query: 534 ASRCDCDHSDG-----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC 588
A C C H G C+P G+C C A +G C C G WG C C C
Sbjct: 1435 ARPCGC-HEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRPCDC-GARLC 1491
Query: 589 LPENGNCVCAPGFRGPSCQRSCQPGRYGKR----CVPCKCANHSF-------CHPSNGTC 637
G C+C P P C CQP +G C C C+ C +G C
Sbjct: 1492 DELTGQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQC 1550
Query: 638 YCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT----CHPQDGSCICPLGWTGHHCLE 693
C TG C C PG G + C CH GT C P G C C G C +
Sbjct: 1551 KCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-D 1608
Query: 694 GCPLGTFGANCSQPCQC------GPGEKC 716
C LGTF + + P C G E+C
Sbjct: 1609 QCSLGTFSLDAANPKGCTRCFCFGATERC 1637
Score = 92.4 bits (228), Expect = 2e-18
Identities = 73/242 (30%), Positives = 90/242 (37%), Gaps = 34/242 (14%)
Query: 191 CQCH-----GAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGG-VFQTP 244
C CH G C+P G C C A G C C+ G GF P+ C G +
Sbjct: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGF--PNCRPCDCGARLCDEL 1494
Query: 245 QGSCSCPPGWMGTICSLPCPEGF--HGPNCSQECRCHNGGL-------CDRFTGQCRCAP 295
G C CPP + C L P+ F H +EC C G+ CD +GQC+C P
Sbjct: 1495 TGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
Query: 296 GYTGDRCREECPVGRFGQDCAETCDC-----APDARCFPANGACLCEHGFTGDRCTDRLC 350
TG RC + C G G CDC AP C P G C C+ G +C C
Sbjct: 1555 NVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGV-CDPLTGQCYCKENVQGPKCDQ--C 1610
Query: 351 PDGFYGLSCQAPCTCDR-------EHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPG 403
G + L P C R E S E + GW L + PG
Sbjct: 1611 SLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPG 1670
Query: 404 CQ 405
+
Sbjct: 1671 TE 1672
Score = 87.0 bits (214), Expect = 8e-17
Identities = 72/233 (30%), Positives = 90/233 (38%), Gaps = 55/233 (23%)
Query: 271 NCSQECRCHN----GGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDAR 326
N ++ C CH G C+ F GQC C G C C G +G CDC
Sbjct: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDC-SRCATGYWGFPNCRPCDC----- 1486
Query: 327 CFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNG--ECSCLP 384
GA LC+ TG +C +CP + C + + CHP+ G EC+C
Sbjct: 1487 -----GARLCDE-LTG-QC---ICPPR----TIPPDCLLCQPQTFGCHPLVGCEECNC-- 1530
Query: 385 GWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYG 444
GPG QE L C SG C+C P TG C C P +G
Sbjct: 1531 ---------------SGPGIQE----LTDPTCDTDSGQCKCRPNVTGRRC-DTCSPGFHG 1570
Query: 445 VNCSARCSCENA----IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNAS 493
C C A C P+ G+C CKE Q C C GT FS +A+
Sbjct: 1571 YPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD-QCSLGT--FSLDAA 1620
Score = 85.5 bits (210), Expect = 2e-16
Identities = 62/211 (29%), Positives = 75/211 (35%), Gaps = 25/211 (11%)
Query: 446 NCSARCSCENAIA----CSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAV 501
N + C C A C P G+C C +CS C G WGF C C +
Sbjct: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRPCDCG-ARL 1490
Query: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFG----EGCASRCDCD-------HSDGCDPVHG 550
C TG C C P C L C FG GC C+C CD G
Sbjct: 1491 CDELTGQCICPPRTIPPDCLL-CQPQTFGCHPLVGC-EECNCSGPGIQELTDPTCDTDSG 1548
Query: 551 RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGT----CLPENGNCVCAPGFRGPSC 606
+C+C+ G RC +C G G C C GT C P G C C +GP C
Sbjct: 1549 QCKCRPNVTGRRCD-TCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC 1607
Query: 607 QRSCQPGRYGKRCVPCKCANHSFCHPSNGTC 637
+ C G + K FC + C
Sbjct: 1608 DQ-CSLGTFSLDAANPKGCTRCFCFGATERC 1637
Score = 79.7 bits (195), Expect = 1e-14
Identities = 69/229 (30%), Positives = 81/229 (35%), Gaps = 80/229 (34%)
Query: 114 CVAPNQCQCVPGWRGDDCSSECAPGMWG-PQCDKPCSCGNNSS----CDPKSGVCSC--- 165
C A C+C PG+ G C EC+PG G P C PC C S CDP+SG CSC
Sbjct: 644 CGAGGLCRCRPGYTGTACQ-ECSPGFHGFPSC-VPCHCSAEGSLHAACDPRSGQCSCRPR 701
Query: 166 -------------------------PSGLQP--------------------PNCLQPCTP 180
P+GL P P+C C P
Sbjct: 702 VTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC-DRCKP 760
Query: 181 GYYG-----PACQFRCQCH-------GAPCDPQTGACFCPAERTGPSCDVSCSQGTSG-- 226
G++G P RC C A C P TG CFC G +C SC G G
Sbjct: 761 GFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLD 819
Query: 227 ----FFCPSTHSCQNGGVF----QTPQGSCSCPPGWMGTICSLPCPEGF 267
F C S C GG + G C C P G CS P + +
Sbjct: 820 QADYFGCRSCR-CDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
Score = 79.3 bits (194), Expect = 2e-14
Identities = 60/193 (31%), Positives = 73/193 (37%), Gaps = 24/193 (12%)
Query: 494 CQCAHEA-----VCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPV 548
C C HE C P G C C G C C G +G CDC + CD +
Sbjct: 1438 CGC-HEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDCG-ARLCDEL 1494
Query: 549 HGRCQCQAGWMGARCHLSCPE--GLWGVNCSNTCTCKNGG-------TCLPENGNCVCAP 599
G+C C + C L P+ G + C C G TC ++G C C P
Sbjct: 1495 TGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
Query: 600 GFRGPSCQRSCQPGRYG-KRCVPCKCANHS----FCHPSNGTCYCLAGWTGPDCSQPCPP 654
G C +C PG +G RC PC C C P G CYC GP C Q C
Sbjct: 1555 NVTGRRCD-TCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSL 1612
Query: 655 GHWGENCAQTCQC 667
G + + A C
Sbjct: 1613 GTFSLDAANPKGC 1625
Score = 75.1 bits (183), Expect = 3e-13
Identities = 56/175 (32%), Positives = 65/175 (37%), Gaps = 63/175 (36%)
Query: 119 QCQCVPGWRGDDCSSECAPGMWG-PQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCL-- 175
QC C G DCS CA G WG P C +PC CG CD +G C CP PP+CL
Sbjct: 1456 QCPCHAHVIGRDCS-RCATGYWGFPNC-RPCDCGARL-CDELTGQCICPPRTIPPDCLLC 1512
Query: 176 QP-------------------------------------------------CTPGYYG-P 185
QP C+PG++G P
Sbjct: 1513 QPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP 1572
Query: 186 ACQFRCQCHGAP-----CDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSC 235
C+ C CH A CDP TG C+C GP CD CS GT + C
Sbjct: 1573 RCR-PCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD-QCSLGTFSLDAANPKGC 1625
Score = 73.9 bits (180), Expect = 7e-13
Identities = 57/180 (31%), Positives = 64/180 (35%), Gaps = 25/180 (13%)
Query: 575 NCSNTCTCKN----GGTCLPENGNCVCAPGFRGPSCQRSCQPGRYG-KRCVPCKCANHSF 629
N + C C G TC P G C C G C R C G +G C PC C
Sbjct: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDCGAR-L 1490
Query: 630 CHPSNGTCYCLAGWTGPDCSQPCPPGHWGENC---AQTCQCHHGG-------TCHPQDGS 679
C G C C PDC C P +G + + C C G TC G
Sbjct: 1491 CDELTGQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQ 1549
Query: 680 CICPLGWTGHHCLEGCPLGTFGANCSQPCQC-----GPGEKCHPETGACVCPPGHSGAPC 734
C C TG C + C G G +PC C PG C P TG C C G C
Sbjct: 1550 CKCRPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGV-CDPLTGQCYCKENVQGPKC 1607
Score = 53.5 bits (127), Expect = 1e-06
Identities = 56/245 (22%), Positives = 74/245 (30%), Gaps = 59/245 (24%)
Query: 533 CASRCD-CDHSDGCDPVHGRCQCQAGWMGARCHLSCP---EGLWGVNCSNTCTCKNGGTC 588
C D CD D DP +C CQ G C CP + W +N+ C
Sbjct: 302 CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNC 361
Query: 589 LPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDC 648
+C P +S G Y V C +H+ TG +C
Sbjct: 362 YGHATDCYYDPEVDRRRASQSLD-GTYQGGGVCIDCQHHT---------------TGVNC 405
Query: 649 SQPCPPGHW--------GENCAQTCQCHHG---GTCHPQDGSCICPLGWTGHHCLEGCPL 697
+ C PG + + + C C GTC G C C ++G C + C
Sbjct: 406 ER-CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC-DVCAE 463
Query: 698 GTFGANCSQP--------------------CQCGP----GEKCH--PETGACVCPPGHSG 731
G G P C C G C P G C+C P G
Sbjct: 464 GFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQG 523
Query: 732 APCRI 736
C +
Sbjct: 524 THCEL 528
Score = 53.5 bits (127), Expect = 1e-06
Identities = 31/91 (34%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 660 NCAQTCQCHH----GGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEK 715
N A+ C CH G TC P G C C G C C G +G +PC CG
Sbjct: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDCG-ARL 1490
Query: 716 CHPETGACVCPPGHSGAPCRIGIQEPFTVMP 746
C TG C+CPP C + + F P
Sbjct: 1491 CDELTGQCICPPRTIPPDCLLCQPQTFGCHP 1521
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 192 bits (489), Expect = 1e-48
Identities = 106/307 (34%), Positives = 135/307 (43%), Gaps = 48/307 (15%)
Query: 240 VFQTPQGSCSCPPGWM--GTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGY 297
V +P C GW C++P EG P+ C +C + G CRC PG+
Sbjct: 31 VASSPSAELQCCAGWRQKDQECTIPICEG---PDA-----CQKDEVCVK-PGLCRCKPGF 81
Query: 298 TGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRL-------- 349
G C CP +G DC E+C C P +C PA GAC C+ G RC
Sbjct: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRC 141
Query: 350 --------CPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN-------ES 394
C G++ +C+ PC C+ + C G C C PGW G C+
Sbjct: 142 DPATGVCHCEPGWWSSTCRRPCQCNTA-AARCEQATGACVCKPGWWGRRCSFRCNCHGSP 200
Query: 395 CPQDT---------HGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGV 445
C QD+ GP CQ+ C C+ G C A SG C C PG+ G C CP ++GV
Sbjct: 201 CEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGV 259
Query: 446 NCSARCS-CENAIACSPIDGEC-VCKEGWQRGNCSVPCPPGTWGFSCNASC-QCAHEAVC 502
C+ C C++ CSP G C C+ GW C PC PGT+G SC C C H C
Sbjct: 260 QCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEAC 319
Query: 503 SPQTGAC 509
P TG C
Sbjct: 320 EPDTGHC 326
Score = 190 bits (483), Expect = 5e-48
Identities = 100/281 (35%), Positives = 125/281 (44%), Gaps = 41/281 (14%)
Query: 359 CQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQA 418
C+ P C ++ + P G C C PG+ G HC+ CP GP C+E C C G C+
Sbjct: 57 CEGPDACQKDE-VCVKP--GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113
Query: 419 TSGLCQCA----------PGYTGPH--CASL-----CPPDTYGVNCSARCSCENAIA-CS 460
+G CQC P GPH C C P + C C C A A C
Sbjct: 114 ATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCE 173
Query: 461 PIDGECVCKEGWQRGNCSV----------------PCPPGTWGFSCNASCQCAHEAVCSP 504
G CVCK GW CS C PG WG C C+C CS
Sbjct: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR-CSA 232
Query: 505 QTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCD-CDHSDGCDPVHGRCQ-CQAGWMGAR 562
+G CTC PG+ GA C+LPCP G G CA C C H++ C P G C+ C+ GW G +
Sbjct: 233 ASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQ 292
Query: 563 CHLSCPEGLWGVNCSNTCT-CKNGGTCLPENGNCVCAPGFR 602
C C G +G +C C C++G C P+ G+C G R
Sbjct: 293 CQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSGSR 333
Score = 189 bits (480), Expect = 1e-47
Identities = 109/337 (32%), Positives = 138/337 (40%), Gaps = 78/337 (23%)
Query: 88 LQCCHGFYESRGFC-VPLCA--QECVHGR-CVAPNQCQCVPGWRGDDCSSECAPGMWGPQ 143
LQCC G+ + C +P+C C CV P C+C PG+ G CSS C WGP
Sbjct: 39 LQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
Query: 144 CDK------------------------------PCSCGNNSSCDPKSGVCSCPSGLQPPN 173
C + PC+CG + CDP +GVC C G
Sbjct: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSST 158
Query: 174 CLQP------------------CTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPS 215
C +P C PG++G C FRC CHG+PC+ +G C C GP
Sbjct: 159 CRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPE 218
Query: 216 CDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQE 275
C C C G G C+CPPG+ G C LPCP G HG C+
Sbjct: 219 CQQQC-------------ECVRGRC-SAASGECTCPPGFRGARCELPCPAGSHGVQCAHS 264
Query: 276 C-RCHNGGLCDRFTGQCR-CAPGYTGDRCREECPVGRFGQDCAETC-DCAPDARCFPANG 332
C RC + C TG C C PG+ G +C++ C G FG+ C + C C C P G
Sbjct: 265 CGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324
Query: 333 ACLCEHGFTGDRCTDRLCPD------GFYGLSCQAPC 363
C +G R T + F GL+C A C
Sbjct: 325 HC---QRCSGSRDTALIAGSLVPLLLLFLGLACCACC 358
Score = 188 bits (477), Expect = 3e-47
Identities = 105/307 (34%), Positives = 130/307 (42%), Gaps = 51/307 (16%)
Query: 457 IACSPIDGECVCKEGWQRGN--CSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPG 514
+A SP E C GW++ + C++P C C + VC + G C C PG
Sbjct: 31 VASSP-SAELQCCAGWRQKDQECTIPI--------CEGPDACQKDEVCV-KPGLCRCKPG 80
Query: 515 WHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHL--------- 565
+ GAHC CP +G C C C C+P G CQCQA GARC
Sbjct: 81 FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR 140
Query: 566 --------SCPEGLWGVNCSNTCTCKNGGT-CLPENGNCVCAPGFRGPSC---------- 606
C G W C C C C G CVC PG+ G C
Sbjct: 141 CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSP 200
Query: 607 ------QRSCQPGRYGKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGE 659
+ +C+PG +G C C+C C ++G C C G+ G C PCP G G
Sbjct: 201 CEQDSGRCACRPGWWGPECQQQCECV-RGRCSAASGECTCPPGFRGARCELPCPAGSHGV 259
Query: 660 NCAQTC-QCHHGGTCHPQDGSC-ICPLGWTGHHCLEGCPLGTFGANCSQPC-QCGPGEKC 716
CA +C +C H C P GSC C GW G C + C GTFG +C Q C C GE C
Sbjct: 260 QCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEAC 319
Query: 717 HPETGAC 723
P+TG C
Sbjct: 320 EPDTGHC 326
Score = 186 bits (471), Expect = 1e-46
Identities = 101/313 (32%), Positives = 129/313 (41%), Gaps = 46/313 (14%)
Query: 368 EHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAP 427
+H + E C GW Q+ P C+ C VC GLC+C P
Sbjct: 27 QHVCVASSPSAELQCCAGW------RQKDQECTIPICEGPDACQKDEVC-VKPGLCRCKP 79
Query: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVP------- 480
G+ G HC+S CP +G +C C C C P G C C+ C P
Sbjct: 80 GFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG 139
Query: 481 ----------CPPGTWGFSCNASCQCAHEAV-CSPQTGACTCTPGWHGAHC--------- 520
C PG W +C CQC A C TGAC C PGW G C
Sbjct: 140 RCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGS 199
Query: 521 -------QLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG 573
+ C G +G C +C+C C G C C G+ GARC L CP G G
Sbjct: 200 PCEQDSGRCACRPGWWGPECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAGSHG 258
Query: 574 VNCSNTC-TCKNGGTCLPENGNC-VCAPGFRGPSCQRSCQPGRYGKRC-VPC-KCANHSF 629
V C+++C CK+ C P+ G+C C PG+ G CQ+ C PG +G+ C C C +
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
Query: 630 CHPSNGTCYCLAG 642
C P G C +G
Sbjct: 319 CEPDTGHCQRCSG 331
Score = 151 bits (381), Expect = 4e-36
Identities = 85/274 (31%), Positives = 104/274 (37%), Gaps = 60/274 (21%)
Query: 484 GTWGFSCNASCQCAHEAVCSPQTGACTCTPGWH--GAHCQLPCPKGQFGEGCASRCDCDH 541
GT G + Q H V S + C GW C +P +G D
Sbjct: 16 GTQGSELDPKGQ--HVCVASSPSAELQCCAGWRQKDQECTIPICEGP---------DACQ 64
Query: 542 SDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGF 601
D G C+C+ G+ GA C CP WG +C +C C G C P G C
Sbjct: 65 KDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC------ 118
Query: 602 RGPSCQRSCQPGRYGKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCP------- 653
CQ R+G RC PC C H C P+ G C+C GW C +PC
Sbjct: 119 -------QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAAR 171
Query: 654 -----------PGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGA 702
PG WG C+ C CH G C G C C GW +G
Sbjct: 172 CEQATGACVCKPGWWGRRCSFRCNCH-GSPCEQDSGRCACRPGW-------------WGP 217
Query: 703 NCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRI 736
C Q C+C G +C +G C CPPG GA C +
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCEL 250
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 188 bits (477), Expect = 3e-47
Identities = 188/725 (25%), Positives = 249/725 (34%), Gaps = 201/725 (27%)
Query: 105 CAQECVHGRCVAPNQCQCVPGWRGDDCS---SECAPGMWGPQCDKPCSCGNNSSCDPKSG 161
C +CV G C C+ G+ G C +ECA +PC G + S
Sbjct: 284 CIDDCVTGN--PSYTCSCLSGFTGRRCHLDVNECA--------SQPCQNGGTCTHGINSF 333
Query: 162 VCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA--CFCPAERTGPSCDVS 219
C CP+G P C +P C + HG C + G+ C C A TG +C++
Sbjct: 334 RCQCPAGFGGPTCETAQSP------CDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMD 387
Query: 220 CSQGTSGFFCPSTHSCQNGG--VFQTPQGSCSCPPGWMGTICSLPCPEGFHG-PNCSQEC 276
C S C NGG V +C C + G L C G H P+
Sbjct: 388 VDD------C-SPDPCLNGGSCVDLVGNYTCLCAEPFKG----LRCETGDHPVPDACLSA 436
Query: 277 RCHNGGLC-DRFTGQ-CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA- 333
CHNGG C D G C C G+ G CRE P + C+C RC AN
Sbjct: 437 PCHNGGTCVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNGGRCLGANTTL 487
Query: 334 CLCEHGFTGDRCTDRL----------CPDGFYGLSCQAP--CTCDREHSLSCHPMNGECS 381
C C GF G C + CPDG Y + C C +H+ S H + C
Sbjct: 488 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS-HSLPSPCD 546
Query: 382 CLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQA--TSGLCQCAPGYTGPHCASLCP 439
P C +GG C A S C+C G+ G HC P
Sbjct: 547 SDP-------------------------CFNGGSCDAHDDSYTCECPRGFHGKHCEKARP 581
Query: 440 PDTYGVNCSARCSCENAIACSPIDGE--CVCKEGWQRGNCSVPCPPGTWGFSCNASCQCA 497
+ + C N C GE C C + +C + P SC AS C
Sbjct: 582 ------HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD-----SC-ASGPCH 629
Query: 498 HEAVCSPQTG--ACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQ 555
+ C G C C PG+ G HC++ P F C + C+ D C CQ
Sbjct: 630 NGGTCFHYIGKYKCDCPPGFSGRHCEI-APSPCFRSPCVNGGTCEDRD----TDFFCHCQ 684
Query: 556 AGWMGARC--HLSC------------------------------------------PEGL 571
AG+MG RC + C P G+
Sbjct: 685 AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGV 744
Query: 572 WG-------VNCSNTCTCKNGGTCLPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPC 622
W ++ + C +GG+C C+C+ G+ G C+ R R PC
Sbjct: 745 WSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE----RDECRAHPC 800
Query: 623 KCANHSFCHPSNGTCYCLAGWTGPDC--------SQPCPPGHWGENCAQTCQCHHGGTCH 674
+ P C C AG+ G C S PC G +C GG +
Sbjct: 801 RNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGG---------RCESGGGAY 851
Query: 675 PQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPC---QCGPGEKCHPETG--ACVCPPGH 729
C+CP + G+HC S PC CG C G +C C G+
Sbjct: 852 ----LCVCPESFFGYHC----------ETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGY 897
Query: 730 SGAPC 734
+G C
Sbjct: 898 TGEDC 902
Score = 147 bits (371), Expect = 5e-35
Identities = 158/569 (27%), Positives = 203/569 (35%), Gaps = 123/569 (21%)
Query: 220 CSQGTSGFFCPSTHSCQNGG------VFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCS 273
C TS C + C NGG V P +CSC G+ G C L E P
Sbjct: 265 CGHTTS--VCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP--- 319
Query: 274 QECRCHNGGLCDRFTG--QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPAN 331
C NGG C +C+C G+ G C Q +T +C +C N
Sbjct: 320 ----CQNGGTCTHGINSFRCQCPAGFGGPTCET-------AQSPCDTKECQHGGQCQVEN 368
Query: 332 GA--CLCEHGFTGDRC---TDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGE--CSCLP 384
G+ C+C+ G+TG C D PD PC + SC + G C C
Sbjct: 369 GSAVCVCQAGYTGAACEMDVDDCSPD---------PCL----NGGSCVDLVGNYTCLCAE 415
Query: 385 GWAGLHCNESCPQDTHGPGCQEHCLCLHGGVC-QATSG-LCQCAPGYTGPHCASLCPPDT 442
+ GL C D P C +GG C A G +C+C G+ G C P D
Sbjct: 416 PFKGLRCETG---DHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD- 471
Query: 443 YGVNCSARCSCENAIACSPIDGE-CVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAV 501
C C N C + C C G+ + C CN + QC
Sbjct: 472 --------CECRNGGRCLGANTTLCQCPLGF----FGLLCEFEITAMPCNMNTQCPDGGY 519
Query: 502 CSPQTGA--CTCTPGWHGAHCQLPCPKGQFGEGCASRCDCD-HSDGCDPVHGRCQCQAGW 558
C G+ C C + +H LP P + C + CD H D C+C G+
Sbjct: 520 CMEHGGSYLCVCHTDHNASH-SLPSPCDS--DPCFNGGSCDAHDDSYT-----CECPRGF 571
Query: 559 MGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKR 618
G C + P C N TCK G +C C F G R C+ G+
Sbjct: 572 HGKHCEKARPHLCSSGPCRNGGTCKEAG----GEYHCSCPYRFTG----RHCEIGK---- 619
Query: 619 CVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENC---AQTC---QCHHGGT 672
P CA+ CH + GTC+ G D CPPG G +C C C +GGT
Sbjct: 620 --PDSCASGP-CH-NGGTCFHYIGKYKCD----CPPGFSGRHCEIAPSPCFRSPCVNGGT 671
Query: 673 CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPET--------GAC- 723
C +D C C G G C CGP E+ T GA
Sbjct: 672 CEDRDTDFFC-----------HCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
Query: 724 --VCPPGHS-GAPCRIGIQEPFTVMPTTP 749
C G+S AP RI + +P V P
Sbjct: 721 LYACDRGYSLSAPSRIRVCQPHGVWSEPP 749
Score = 100 bits (250), Expect = 5e-21
Identities = 125/509 (24%), Positives = 160/509 (31%), Gaps = 183/509 (35%)
Query: 104 LCAQ-----ECVHGRCVAPNQCQCVPGWRGDDCSS-------ECAPGMWGPQCDK----P 147
LCA+ C G P+ C P G C EC G G C +
Sbjct: 412 LCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD 471
Query: 148 CSCGNNSSC-DPKSGVCSCPSGL-----------QPPNCLQPCTPGYY--GPACQFRCQC 193
C C N C + +C CP G P N C G Y + C C
Sbjct: 472 CECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC 531
Query: 194 HG---------APCDPQTGACF----CPAERTGPSCDVSCSQGTSGFFCP-------STH 233
H +PCD + CF C A +C+ C +G G C S+
Sbjct: 532 HTDHNASHSLPSPCD--SDPCFNGGSCDAHDDSYTCE--CPRGFHGKHCEKARPHLCSSG 587
Query: 234 SCQNGGVFQTPQGS--CSCPPGWMGTICSLPCPEGF-HGPNCSQECRCHNGGLCDRFTGQ 290
C+NGG + G CSCP + G C + P+ GP CHNGG C + G+
Sbjct: 588 PCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGP-------CHNGGTCFHYIGK 640
Query: 291 --CRCAPGYTGDRCRE-------------------------ECPVGRFGQDCAETCDCAP 323
C C PG++G C C G G+ C DC P
Sbjct: 641 YKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP 700
Query: 324 DARCFPA----NGACL-------CEHGFT------------------------------- 341
A NG L C+ G++
Sbjct: 701 PEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQ 760
Query: 342 ----GDRCTDR------LCPDGFYGLSCQAPCTCDREHSL----SCHPMNGE--CSCLPG 385
G C DR LC G+ G C+ R H SC + G C C G
Sbjct: 761 PCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAG 820
Query: 386 WAGLHCNES-------------------------CPQDTHGPGCQ---EHCL---CLHGG 414
+ G+HC CP+ G C+ + C C G
Sbjct: 821 FVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRG 880
Query: 415 VCQATSGL--CQCAPGYTGPHCA-SLCPP 440
C A++G C C GYTG CA L PP
Sbjct: 881 YCLASNGSHSCTCKVGYTGEDCAKELFPP 909
Score = 43.1 bits (100), Expect = 0.001
Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 3/38 (7%)
Query: 575 NCSNTCTCKNGGTCLP--ENGNCVCAPGFRGPSCQRSC 610
NCS C+NGGTC+P + +C C PGF+G C+ +C
Sbjct: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 35.0 bits (79), Expect = 0.37
Identities = 21/70 (30%), Positives = 28/70 (40%), Gaps = 8/70 (11%)
Query: 271 NCSQECRCHNGGLC--DRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCF 328
NCS+ C NGG C C C PG+ G RC C + + C + + F
Sbjct: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELACI--KVSRPCTRLFS---ETKAF 1363
Query: 329 PANGACLCEH 338
P +C H
Sbjct: 1364 PVWEGGVCHH 1373
Score = 32.3 bits (72), Expect = 2.4
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 231 STHSCQNGG--VFQTPQGSCSCPPGWMGTICSLPC 263
S + CQNGG V SC C PG+ G C L C
Sbjct: 1312 SENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 31.2 bits (69), Expect = 5.3
Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 7/43 (16%)
Query: 110 VHGRCVAPNQCQ----CVPGWRGDDCSSECAPGMWGPQCDKPC 148
V G C + N CQ CVPG D S +C PG G +C+ C
Sbjct: 1307 VPGNC-SENPCQNGGTCVPG--ADAHSCDCGPGFKGRRCELAC 1346
Score = 31.2 bits (69), Expect = 5.3
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 13/57 (22%)
Query: 654 PGHWGENCAQTCQCHHGGTCHP--QDGSCICPLGWTGHHCLEGCPLGTFGANCSQPC 708
PG+ EN C +GGTC P SC C G+ G C C S+PC
Sbjct: 1308 PGNCSEN-----PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC------IKVSRPC 1353
Score = 30.4 bits (67), Expect = 9.0
Identities = 13/33 (39%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 496 CAHEAVCSPQTGA--CTCTPGWHGAHCQLPCPK 526
C + C P A C C PG+ G C+L C K
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIK 1348
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 164 bits (415), Expect = 4e-40
Identities = 135/419 (32%), Positives = 168/419 (40%), Gaps = 84/419 (20%)
Query: 276 CRCHN----GGLCDRFTGQCRCAPGYTGDRCREECPVGRF--GQDCAETCDCAP----DA 325
C+CH G C R GQC+C P G RC + C G + G C C P D
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVG-RCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
Query: 326 RCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPG 385
C G C C +G RC DR C G++G PC C+R L C P G C G
Sbjct: 828 VCDQVTGQCPCHGEVSGRRC-DR-CLAGYFGFPSCHPCPCNRFAEL-CDPETGSCFNCGG 884
Query: 386 WA-GLHCNESC-----PQDTHGPGCQEHCLC----------LHGGVCQATSG--LCQCAP 427
+ G +C E C + G C+ CLC H S +C C
Sbjct: 885 FTTGRNC-ERCIDGYYGNPSSGQPCRP-CLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQ 942
Query: 428 GYTGPHCASLCP-----PDTYGVNCSARCSCENAI------ACSPIDGECV-CKEGWQRG 475
GYTG C P G C C+C N I +CS + GEC+ C Q
Sbjct: 943 GYTGTQCGECSTGFYGNPRISGAPCQP-CACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
Query: 476 NCSVPCPPGTWGFSCNASCQ-CAHEA---------------VCSPQTGACTCTPGWHGAH 519
NC + C PG +G + N +C+ C+ A +C P TGAC C P G
Sbjct: 1002 NCQL-CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLA 1060
Query: 520 CQLPCPKGQF----GEGCASRCDCD----HSDGCDPVHGRCQCQAGWMGARCHLSCPEGL 571
C C G + G GC S CDCD S CD + G+C C+ G+ G RC C E
Sbjct: 1061 CDR-CADGYWNLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-ECQENY 1117
Query: 572 WGVNCSN--TCTCKNGGT----CLPENGNCVCAPGFRGPSCQRSCQPGRYGK--RCVPC 622
+G C C GT C P+ G C C G G C R C G + C+ C
Sbjct: 1118 YGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR-CARGHSQEFPTCLQC 1175
Score = 123 bits (309), Expect = 8e-28
Identities = 117/408 (28%), Positives = 144/408 (35%), Gaps = 85/408 (20%)
Query: 119 QCQCVPGWRGDDCSSECAPGMW--GPQCDKPCSCGNNSS----CDPKSGVCSCPSGLQPP 172
QCQC P G C C+ G + G PC C S CD +G C C +
Sbjct: 787 QCQCKPLVVGR-CCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGR 845
Query: 173 NCLQPCTPGYYG-PACQFRCQCH--GAPCDPQTGACF-CPAERTGPSCDVSCSQGTSGFF 228
C C GY+G P+C C C+ CDP+TG+CF C TG +C+ C G G
Sbjct: 846 RC-DRCLAGYFGFPSCH-PCPCNRFAELCDPETGSCFNCGGFTTGRNCE-RCIDGYYGN- 901
Query: 229 CPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFT 288
PS+ P C CP P + +C Q +
Sbjct: 902 -PSSGQ---------PCRPCLCPDD--------PSSNQYFAHSCYQNLWSSDV------- 936
Query: 289 GQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDA-----------RCFPANGACL-C 336
C C GYTG +C E C G +G C P A C G CL C
Sbjct: 937 -ICNCLQGYTGTQCGE-CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRC 994
Query: 337 EHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS--------------CHPMNGECSC 382
H G C +LC G YG + C H+ C P+ G C C
Sbjct: 995 LHNTQGANC--QLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052
Query: 383 LPGWAGLHCNESCP---QDTHGPGCQEHCLC----LHGGVCQATSGLCQCAPGYTGPHCA 435
LP GL C+ G GCQ C C C +G C C GY G C
Sbjct: 1053 LPNVTGLACDRCADGYWNLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCPCKLGYGGKRC- 1110
Query: 436 SLCPPDTYG------VNCSARCSCENAIACSPIDGECVCKEGWQRGNC 477
S C + YG + C + C P G C C+EG C
Sbjct: 1111 SECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRC 1158
Score = 123 bits (308), Expect = 1e-27
Identities = 109/399 (27%), Positives = 140/399 (35%), Gaps = 77/399 (19%)
Query: 404 CQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVN------CSARCSCENAI 457
C+ H G C G CQC P G C C +Y + C
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVG-RCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
Query: 458 ACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEA-VCSPQTGAC-TCTPGW 515
C + G+C C G G C G +GF C C A +C P+TG+C C
Sbjct: 828 VCDQVTGQCPC-HGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFT 886
Query: 516 HGAHCQLPCPKGQFGEGCASR------CDCDHSDGCDPVHGR----------CQCQAGWM 559
G +C+ C G +G + + C D S H C C G+
Sbjct: 887 TGRNCER-CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYT 945
Query: 560 GARCHLSCPEGLWG-----------VNCSNTCTCKNGGTCLPENGNCV-CAPGFRGPSCQ 607
G +C C G +G C+N + +C G C+ C +G +CQ
Sbjct: 946 GTQCG-ECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ 1004
Query: 608 RSCQPGRYG----KRCVPCKC-------------ANHSFCHPSNGTCYCLAGWTGPDCSQ 650
C+PG YG + C C C C P G C CL TG C +
Sbjct: 1005 L-CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDR 1063
Query: 651 PCPPGHW----GENCAQTCQCH----HGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFG- 701
C G+W G C Q+C C C G C C LG+ G C E C +G
Sbjct: 1064 -CADGYWNLVPGRGC-QSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE-CQENYYGD 1120
Query: 702 --ANCSQPCQCGPGEK----CHPETGACVCPPGHSGAPC 734
C PC C C P+TG C C G SG C
Sbjct: 1121 PPGRCI-PCDCNRAGTQKPICDPDTGMCRCREGVSGQRC 1158
Score = 101 bits (252), Expect = 3e-21
Identities = 91/301 (30%), Positives = 118/301 (39%), Gaps = 62/301 (20%)
Query: 489 SCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG---EGCASRCDCDHSDG- 544
+C Q + + CS G C C P G C C G + GC C C H G
Sbjct: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHP-CHC-HPQGS 824
Query: 545 ----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKN-GGTCLPENGNCVCAP 599
CD V G+C C G RC C G +G + C C C PE G+C
Sbjct: 825 KDTVCDQVTGQCPCHGEVSGRRCD-RCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCG 883
Query: 600 GFR-GPSCQRSCQPGRYG-----KRCVPCKC-----ANHSFCHP-------SNGTCYCLA 641
GF G +C+R C G YG + C PC C +N F H S+ C CL
Sbjct: 884 GFTTGRNCER-CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQ 942
Query: 642 GWTGPDCSQPCPPGHWGENC-----AQTCQCHHG------GTCHPQDGSCI-CPLGWTGH 689
G+TG C + C G +G Q C C++ +C G C+ C G
Sbjct: 943 GYTGTQCGE-CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
Query: 690 HCLEGCPLGTFGANCSQPC-------------QCGPGEK---CHPETGACVCPPGHSGAP 733
+C + C G +G+ +Q C +C PG C P TGAC C P +G
Sbjct: 1002 NC-QLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLA 1060
Query: 734 C 734
C
Sbjct: 1061 C 1061
Score = 77.8 bits (190), Expect = 5e-14
Identities = 76/291 (26%), Positives = 100/291 (34%), Gaps = 59/291 (20%)
Query: 451 CSCE-NAIACSPID---GECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSP-- 504
C C +A C P+ G+ G G C C T G +C +A P
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV--CQHNTDGPNCERCKDFFQDAPWRPAA 322
Query: 505 --QTGAC-TCTPGWHGAHCQLPCP--------KGQFGEGCASRCDCDHSDGCDPVHGRCQ 553
Q AC +C+ H + C G E C + H D C P+ R
Sbjct: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDP 382
Query: 554 CQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPEN--------GNCVCAPGFRGPS 605
+ +S P C T +GG C+ + G C+C G
Sbjct: 383 LKT--------ISDPYACIPCECDPDGTI-SGGICVSHSDPALGSVAGQCLCKENVEGAK 433
Query: 606 CQRSCQPGRYGKR------CVPCKC-----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPP 654
C + C+P YG C PC C C G C CL+ TG C + C
Sbjct: 434 CDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTV 491
Query: 655 GHWG-----ENCAQTCQCHHGGT----CHPQDGSCICPLGWTGHHCLEGCP 696
G+WG C+ C C GG C P++G C C TG C E P
Sbjct: 492 GYWGLGNHLHGCSP-CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAP 541
Score = 75.1 bits (183), Expect = 3e-13
Identities = 83/323 (25%), Positives = 109/323 (33%), Gaps = 62/323 (19%)
Query: 355 YGLSCQAPCTCDREHSLSCHPMN---GECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCL 411
Y + + C C+ H+ C PM G+ PG C C +T GP C E C
Sbjct: 257 YEMIVRGSCFCNG-HASECRPMQKMRGDVFSPPGMVHGQC--VCQHNTDGPNC-ERC--- 309
Query: 412 HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEG 471
Q AP P N CSC + + D G
Sbjct: 310 --------KDFFQDAPWR---------PAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
Query: 472 WQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE 531
G C T G C+ + + C P C+ P G
Sbjct: 353 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP------CECD-PDGTISG 405
Query: 532 G-CASRCDCDHSD-GCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNT-----CTCKN 584
G C S HSD V G+C C+ GA+C C +G++ ++ C C
Sbjct: 406 GICVS-----HSDPALGSVAGQCLCKENVEGAKCD-QCKPNHYGLSATDPLGCQPCDCNP 459
Query: 585 GG-----TCLPENGNCVCAPGFRGPSCQRSCQPGRYG-----KRCVPCKC----ANHSFC 630
G TC + G C+C G C+ C G +G C PC C A + C
Sbjct: 460 LGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHLHGCSPCDCDIGGAYSNVC 518
Query: 631 HPSNGTCYCLAGWTGPDCSQPCP 653
P NG C C TG CS+P P
Sbjct: 519 SPKNGQCECRPHVTGRSCSEPAP 541
Score = 74.3 bits (181), Expect = 5e-13
Identities = 83/295 (28%), Positives = 100/295 (33%), Gaps = 75/295 (25%)
Query: 493 SCQC-AHEAVCSPQT---GACTCTPGWHGAHCQLPCPKGQFGEGCASRC-----DCDHSD 543
SC C H + C P G PG H Q C G C RC D
Sbjct: 264 SCFCNGHASECRPMQKMRGDVFSPPGM--VHGQCVCQHNTDGPNC-ERCKDFFQDAPWRP 320
Query: 544 GCDPVHGRCQ-CQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFR 602
D C+ C +RCH L S GG C C
Sbjct: 321 AADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLS-------GGVCED------CQHNTE 367
Query: 603 GPSCQRSCQPGRYGK---------RCVPCKC-----------ANHSFCHPSNGT----CY 638
G C R C+P Y C+PC+C +HS P+ G+ C
Sbjct: 368 GQHCDR-CRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHS--DPALGSVAGQCL 424
Query: 639 CLAGWTGPDCSQPCPPGHWGENCA-----QTCQCHHGG-----TCHPQDGSCICPLGWTG 688
C G C Q C P H+G + Q C C+ G TC G C+C TG
Sbjct: 425 CKENVEGAKCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTG 483
Query: 689 HHCLEGCPLGTFGAN-----CSQPCQCGPG----EKCHPETGACVCPPGHSGAPC 734
HC E C +G +G CS PC C G C P+ G C C P +G C
Sbjct: 484 AHC-EECTVGYWGLGNHLHGCS-PCDCDIGGAYSNVCSPKNGQCECRPHVTGRSC 536
Score = 72.0 bits (175), Expect = 3e-12
Identities = 64/257 (24%), Positives = 90/257 (35%), Gaps = 69/257 (26%)
Query: 331 NGACLCEHGFTGDRCTDRLCPDGFYGL-----------SCQAPCTCDREHSLSCHPMNGE 379
+G C+C+H G C C D F +C++ C+C+ HS CH
Sbjct: 292 HGQCVCQHNTDGPNC--ERCKDFFQDAPWRPAADLQDNACRS-CSCN-SHSSRCHFDMTT 347
Query: 380 CSCLPGWAGLHCNESCPQDTHGPGCQE--------------------HCLC-----LHGG 414
G +G C E C +T G C C C + GG
Sbjct: 348 YLASGGLSGGVC-EDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGG 406
Query: 415 VCQATS--------GLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENA---------- 456
+C + S G C C G C C P+ YG++ + C+
Sbjct: 407 ICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPF 465
Query: 457 IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCN----ASCQC----AHEAVCSPQTGA 508
+ C G+C+C +C C G WG + + C C A+ VCSP+ G
Sbjct: 466 LTCDVDTGQCLCLSYVTGAHCE-ECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQ 524
Query: 509 CTCTPGWHGAHCQLPCP 525
C C P G C P P
Sbjct: 525 CECRPHVTGRSCSEPAP 541
Score = 64.7 bits (156), Expect = 4e-10
Identities = 80/268 (29%), Positives = 96/268 (35%), Gaps = 50/268 (18%)
Query: 110 VHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCD------KPCSCGNNSS-CDPKSGV 162
VHG+CV + G + C W P D + CSC ++SS C
Sbjct: 291 VHGQCVCQHNTD---GPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTT 347
Query: 163 CSCPSGLQPPNCLQPCTPGYYGPACQFRCQ--CHGAPCDPQTGACFC-PAERTGPSCDVS 219
GL C + C G C RC+ + P + C P E CD
Sbjct: 348 YLASGGLSGGVC-EDCQHNTEGQHCD-RCRPLFYRDPLKTISDPYACIPCE-----CD-- 398
Query: 220 CSQGT-SGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG-----PNCS 273
GT SG C S G V G C C G C C +G P
Sbjct: 399 -PDGTISGGICVSHSDPALGSV----AGQCLCKENVEGAKCD-QCKPNHYGLSATDPLGC 452
Query: 274 QECRCHNGG-----LCDRFTGQCRCAPGYTGDRCREECPVGRFG-----QDCAETCDC-- 321
Q C C+ G CD TGQC C TG C EEC VG +G C+ CDC
Sbjct: 453 QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHC-EECTVGYWGLGNHLHGCSP-CDCDI 510
Query: 322 --APDARCFPANGACLCEHGFTGDRCTD 347
A C P NG C C TG C++
Sbjct: 511 GGAYSNVCSPKNGQCECRPHVTGRSCSE 538
Score = 63.9 bits (154), Expect = 7e-10
Identities = 44/132 (33%), Positives = 52/132 (39%), Gaps = 19/132 (14%)
Query: 120 CQCVPGWRGDDCSSECAPGMWG-------PQCDKPCSCGNNSSCDPKSGVCSCPSGLQPP 172
C C+P G C CA G W CD +S CD +G C C G
Sbjct: 1050 CPCLPNVTGLACD-RCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGK 1108
Query: 173 NCLQPCTPGYYG--PACQFRCQCHGAP-----CDPQTGACFCPAERTGPSCDVSCSQGTS 225
C + C YYG P C C+ A CDP TG C C +G CD C++G S
Sbjct: 1109 RCSE-CQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCD-RCARGHS 1166
Query: 226 GFF--CPSTHSC 235
F C H C
Sbjct: 1167 QEFPTCLQCHLC 1178
Score = 53.1 bits (126), Expect = 1e-06
Identities = 45/160 (28%), Positives = 58/160 (36%), Gaps = 42/160 (26%)
Query: 147 PCSCGNN---------SSCDPK----SGVCSCPSGLQPPNCLQPCTPGYYGPA------C 187
PC C + S DP +G C C ++ C Q C P +YG + C
Sbjct: 394 PCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGC 452
Query: 188 QFRCQCHGA------PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTH-------S 234
Q C C+ CD TG C C + TG C+ + T G++ H
Sbjct: 453 Q-PCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE----ECTVGYWGLGNHLHGCSPCD 507
Query: 235 CQNGGVFQT----PQGSCSCPPGWMGTICSLPCPEGFHGP 270
C GG + G C C P G CS P P F P
Sbjct: 508 CDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 42.0 bits (97), Expect = 0.003
Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 115 VAPNQCQCVPGWRGDDCSSECAPGMWG-----PQCDKPCSC----GNNSSCDPKSGVCSC 165
V QC C+ G C EC G WG C PC C ++ C PK+G C C
Sbjct: 470 VDTGQCLCLSYVTGAHCE-ECTVGYWGLGNHLHGCS-PCDCDIGGAYSNVCSPKNGQCEC 527
Query: 166 PSGLQPPNCLQPCTPGYY 183
+ +C +P PGY+
Sbjct: 528 RPHVTGRSCSEP-APGYF 544
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 163 bits (412), Expect = 9e-40
Identities = 143/488 (29%), Positives = 183/488 (37%), Gaps = 111/488 (22%)
Query: 120 CQCVPGWRGDDCSSECAPG-------MWGPQCDKPCSC-GNNSSCDPKSGVC-SCPSGLQ 170
CQC PG+ G C S C P ++G C+ PC C G+ SCD +G C +C
Sbjct: 724 CQCPPGYTGSSCES-CWPRHRRVNGTIFGGICE-PCQCFGHAESCDDVTGECLNCKDHTG 781
Query: 171 PPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP 230
P C C PG+YG + + C P P+ P+C + S G C
Sbjct: 782 GPYC-DKCLPGFYGEPTKGTSE----DCQPCACPLNIPSNNFSPTCHLDRSLG---LICD 833
Query: 231 STHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP-----NCSQECRCHNG---- 281
CP G+ G C C EG+ G Q C+C++
Sbjct: 834 G------------------CPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFS 874
Query: 282 --GLCDRFTGQCR-CAPGYTGDRCREECPVGRFGQDCAETCDCAP---------DARCFP 329
G CD +G C C PG TG C E C G FG D + +C P C
Sbjct: 875 IPGSCDSLSGSCLICKPGTTGRYC-ELCADGYFG-DAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 330 ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQ---APCTCDR--EHSLSCHPMNGECSCLP 384
G C C G RC C G +GL PC C+ S C +G+C C P
Sbjct: 933 QTGQCECRANVQGQRCDK--CKAGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQP 989
Query: 385 GWAGLHCNESCPQDTHG------PGCQEHCLCLH-GGVCQATSGLCQCAPGYTGPHCASL 437
G G + C + HG GC C C H G C +G C C P G C S
Sbjct: 990 GVTG----KKCDRCAHGYFNFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGEKC-SK 1043
Query: 438 CPPDTYGVNCSARCSCENAIACSPID-------GECVCKEGWQRGNCSVPCPPGTWGFSC 490
C P+T+G + + C N +D G+C C + C+ C G W +
Sbjct: 1044 CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCT-ECSRGHWNYPR 1102
Query: 491 NASCQC-------------AHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG------E 531
C C + CS QTG CTC G HC C G+FG
Sbjct: 1103 CNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPL 1161
Query: 532 GCASRCDC 539
GC+S C C
Sbjct: 1162 GCSS-CYC 1168
Score = 163 bits (412), Expect = 9e-40
Identities = 143/487 (29%), Positives = 183/487 (37%), Gaps = 114/487 (23%)
Query: 291 CRCAPGYTGDRCREECPVGR------FGQDCAETCDCAPDAR-CFPANGACLCEHGFTGD 343
C+C PGYTG C P R FG C E C C A C G CL TG
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDHTGG 782
Query: 344 RCTDRLCPDGFYGL-------SCQAPCTC-----DREHSLSCHPMNGECSCLPGWAGLHC 391
D+ P GFYG CQ PC C S +CH L GL C
Sbjct: 783 PYCDKCLP-GFYGEPTKGTSEDCQ-PCACPLNIPSNNFSPTCH--------LDRSLGLIC 832
Query: 392 NESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARC 451
+ CP GP C+ +CA GY G P G +C C
Sbjct: 833 -DGCPVGYTGPRCE------------------RCAEGYFGQ-------PSVPGGSCQP-C 865
Query: 452 SCENAI------ACSPIDGEC-VCKEGWQRGNCSVPCPPGTWGFSCNAS----CQC---- 496
C + + +C + G C +CK G C + C G +G + +A C+C
Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL-CADGYFGDAVDAKNCQPCRCNAGG 924
Query: 497 AHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG----EGCASRCDCDH----SDGCDPV 548
+ VC QTG C C G C C G FG GC C+C+ S C+
Sbjct: 925 SFSEVCHSQTGQCECRANVQGQRCD-KCKAGTFGLQSARGCVP-CNCNSFGSKSFDCEE- 981
Query: 549 HGRCQCQAGWMGARCHLSCPEGLWGVN---CSNTCTCKN-GGTCLPENGNCVCAPGFRGP 604
G+C CQ G G +C C G + C+ C C + G C P+ G C+C P G
Sbjct: 982 SGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCT-ACECSHLGNNCDPKTGRCICPPNTIGE 1039
Query: 605 SCQRSCQPGRYGKR----CVPCKCANHSF----CHPSNGTCYCLAGWTGPDCSQPCPPGH 656
C + C P +G C C C+ C+ + G C C ++G C++ C GH
Sbjct: 1040 KCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGH 1097
Query: 657 WGENCAQTCQCHHGGT-------------CHPQDGSCICPLGWTGHHCLEGCPLGTFGAN 703
W C C GT C Q G C C + G HC + C G FG +
Sbjct: 1098 WNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHC-DRCRPGKFGLD 1156
Query: 704 CSQPCQC 710
P C
Sbjct: 1157 AKNPLGC 1163
Score = 147 bits (370), Expect = 7e-35
Identities = 115/384 (29%), Positives = 158/384 (41%), Gaps = 71/384 (18%)
Query: 414 GVCQATSGLCQCAPGYTGPHCASLCPPDT------YGVNCSARCSC-ENAIACSPIDGEC 466
G A +CQC PGYTG C S P +G C C C +A +C + GEC
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEP-CQCFGHAESCDDVTGEC 773
Query: 467 V-CKEGWQRGNCSVPCPPGTWGFSCNAS------CQCAHEAVCSPQTGACT--------- 510
+ CK+ C C PG +G + C C + + C
Sbjct: 774 LNCKDHTGGPYCD-KCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832
Query: 511 --CTPGWHGAHCQLPCPKGQFGE-----GCASRCDCDHS------DGCDPVHGRCQ-CQA 556
C G+ G C+ C +G FG+ G C C+ + CD + G C C+
Sbjct: 833 DGCPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP 891
Query: 557 GWMGARCHLSCPEGLWG-----VNCSNTCTCKNGGT----CLPENGNCVCAPGFRGPSCQ 607
G G C L C +G +G NC C C GG+ C + G C C +G C
Sbjct: 892 GTTGRYCEL-CADGYFGDAVDAKNCQ-PCRCNAGGSFSEVCHSQTGQCECRANVQGQRCD 949
Query: 608 RSCQPGRYG----KRCVPCKC---ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWG-- 658
+ C+ G +G + CVPC C + SF +G C+C G TG C + C G++
Sbjct: 950 K-CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDR-CAHGYFNFQ 1007
Query: 659 ENCAQTCQCHH-GGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS---QPCQCGP-- 712
E C+C H G C P+ G CICP G C + C T+G + + + C C
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVG 1066
Query: 713 --GEKCHPETGACVCPPGHSGAPC 734
+C+ TG C C P SGA C
Sbjct: 1067 SLDFQCNVNTGQCNCHPKFSGAKC 1090
Score = 90.9 bits (224), Expect = 6e-18
Identities = 80/286 (27%), Positives = 104/286 (36%), Gaps = 68/286 (23%)
Query: 119 QCQCVPGWRGDDCSSECAPGMWGPQCDK---PCSC---GNNSSCDPKSGVCSCPSGLQPP 172
QC+C +G C +C G +G Q + PC+C G+ S +SG C C G+
Sbjct: 936 QCECRANVQGQRCD-KCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGK 994
Query: 173 NCLQPCTPGYY----GPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFF 228
C C GY+ G C G CDP+TG C CP G C C+ T G
Sbjct: 995 KC-DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCS-KCAPNTWG-- 1050
Query: 229 CPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFT 288
HS G +C+C T+ SL C+ T
Sbjct: 1051 ----HSITTG------CKACNC-----STVGSLDFQ-------------------CNVNT 1076
Query: 289 GQCRCAPGYTGDRCREECPVGRFGQDCAETCDC-------------APDARCFPANGACL 335
GQC C P ++G +C EC G + CDC C G C
Sbjct: 1077 GQCNCHPKFSGAKC-TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT 1135
Query: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECS 381
C+ G C DR C G +GL + P C S C +CS
Sbjct: 1136 CKVNVEGIHC-DR-CRPGKFGLDAKNPLGCS---SCYCFGTTTQCS 1176
Score = 79.0 bits (193), Expect = 2e-14
Identities = 64/207 (30%), Positives = 81/207 (39%), Gaps = 47/207 (22%)
Query: 571 LWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGR-------YGKRCVPCK 623
L VN + + G+ C C PG+ G SC+ SC P +G C PC+
Sbjct: 700 LSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCE-SCWPRHRRVNGTIFGGICEPCQ 758
Query: 624 CANHS-FCHPSNGTCYCLAGWTGPDCSQPCPPGHWGE------NCAQTCQC-------HH 669
C H+ C G C TG C PG +GE Q C C +
Sbjct: 759 CFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNF 818
Query: 670 GGTCHPQ-------DGSCICPLGWTGHHCLEGCPLGTFG-----ANCSQPCQCG------ 711
TCH DG CP+G+TG C E C G FG QPCQC
Sbjct: 819 SPTCHLDRSLGLICDG---CPVGYTGPRC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFS 874
Query: 712 -PGEKCHPETGAC-VCPPGHSGAPCRI 736
PG C +G+C +C PG +G C +
Sbjct: 875 IPG-SCDSLSGSCLICKPGTTGRYCEL 900
Score = 77.0 bits (188), Expect = 8e-14
Identities = 55/180 (30%), Positives = 70/180 (38%), Gaps = 42/180 (23%)
Query: 595 CVCAPGFRGPSCQRSCQPGRYGKR--------------CVPCKCANHS-FCHPSNGTCYC 639
C C G+ G SC+ +C PG Y R CVPC+C HS C P C
Sbjct: 1380 CDCPLGYSGLSCE-ACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 640 LAGWTGPDCSQPCPPGHWG-----ENCAQTCQCHHGGTCHPQDGSCI-----------CP 683
T D + C G++G N Q C C + + SC+ CP
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 684 LGWTGHHCLEGCP-----LGTFGANCSQPCQCGPGEK----CHPETGACVCPPGHSGAPC 734
G+ G +C P G G +C Q C+C P C P TG C C PG +G C
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSC-QECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Score = 72.8 bits (177), Expect = 2e-12
Identities = 76/285 (26%), Positives = 111/285 (38%), Gaps = 67/285 (23%)
Query: 53 EPCERPWEGPHTCPQPTVVYRTVYRQ----VVKTDHRQRLQCCHGFY--ESRGFCVPLCA 106
E E+ W+ P+ V+RTV R+ ++ H ++ +G + +SR + +
Sbjct: 1305 EMTEKEWKYYGDDPR---VHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 107 QECVHGRCVAP-----NQCQCVPGWRGDDCSSECAPGMW-----------GPQCDK--PC 148
E G + P +C C G+ G C + C PG + GP PC
Sbjct: 1362 AEQGRGTTMTPPADLIEKCDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPC 1420
Query: 149 SC-GNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFC 207
C G++S CDP++ +C + + C GYYG G P D Q C C
Sbjct: 1421 QCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIV-------KGLPNDCQQ--CAC 1471
Query: 208 PAERTGPSCDVSC-SQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCP-- 264
P + + SC ++G + C + CP G+ G C P
Sbjct: 1472 PLISSSNNFSPSCVAEGLDDYRCTA------------------CPRGYEGQYCERCAPGY 1513
Query: 265 ---EGFHGPNCSQECRCHNGGL----CDRFTGQCRCAPGYTGDRC 302
G G +C QEC C G CD TG C C PG TG +C
Sbjct: 1514 TGSPGNPGGSC-QECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Score = 69.7 bits (169), Expect = 1e-11
Identities = 73/239 (30%), Positives = 87/239 (36%), Gaps = 69/239 (28%)
Query: 163 CSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPS--CDVSC 220
C CP G +C + C PG+Y + R Q G P G C P + G S CD
Sbjct: 1380 CDCPLGYSGLSC-EACLPGFY----RLRSQPGGRTPGPTLGTCV-PCQCNGHSSLCD--- 1430
Query: 221 SQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG-----PNCSQE 275
P T CQN C G C C G++G PN Q+
Sbjct: 1431 ---------PETSICQN------------CQHHTAGDFCER-CALGYYGIVKGLPNDCQQ 1468
Query: 276 CRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACL 335
C C + F+ C A G RC CP G GQ C CAP
Sbjct: 1469 CACPLISSSNNFSPSC-VAEGLDDYRCTA-CPRGYEGQYCER---CAP------------ 1511
Query: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS--CHPMNGECSCLPGWAGLHCN 392
G+TG G G SCQ C CD SL C P+ G C+C PG G C+
Sbjct: 1512 ---GYTGS--------PGNPGGSCQE-CECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 60.1 bits (144), Expect = 1e-08
Identities = 65/252 (25%), Positives = 81/252 (32%), Gaps = 77/252 (30%)
Query: 350 CPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGP--GCQEH 407
CP G+ GLSC+A CLPG+ L T GP G
Sbjct: 1382 CPLGYSGLSCEA--------------------CLPGFYRLRSQPG--GRTPGPTLGTCVP 1419
Query: 408 CLCL-HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGV-----NCSARCSCENAIACSP 461
C C H +C + +CQ +T C YG+ N +C+C + +
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNN 1479
Query: 462 IDGECV-----------CKEGWQRGNCSVPCP-----PGTWGFSCNASCQC----AHEAV 501
CV C G++ C P PG G SC C+C +
Sbjct: 1480 FSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ-ECECDPYGSLPVP 1538
Query: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
C P TG CTC PG G C DGC H R GW
Sbjct: 1539 CDPVTGFCTCRPGATGRKC----------------------DGCKHWHAR----EGWECV 1572
Query: 562 RCHLSCPEGLWG 573
C C L G
Sbjct: 1573 FCGDECTGLLLG 1584
Score = 54.3 bits (129), Expect = 6e-07
Identities = 55/170 (32%), Positives = 66/170 (38%), Gaps = 47/170 (27%)
Query: 90 CCHGFYESR------------GFCVPLCAQECVHGRCVAPNQ--CQ-CVPGWRGDDCSSE 134
C GFY R G CVP Q H P CQ C GD C
Sbjct: 1394 CLPGFYRLRSQPGGRTPGPTLGTCVP--CQCNGHSSLCDPETSICQNCQHHTAGDFCE-R 1450
Query: 135 CAPGMWG-----PQCDKPCSCGNNSSCDPKSGVC-----------SCPSGLQPPNCLQPC 178
CA G +G P + C+C SS + S C +CP G + C + C
Sbjct: 1451 CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYC-ERC 1509
Query: 179 TPGYYGP------ACQFRCQC--HGA---PCDPQTGACFCPAERTGPSCD 217
PGY G +CQ C+C +G+ PCDP TG C C TG CD
Sbjct: 1510 APGYTGSPGNPGGSCQ-ECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 49.7 bits (117), Expect = 1e-05
Identities = 70/270 (25%), Positives = 89/270 (32%), Gaps = 98/270 (36%)
Query: 290 QCRCAPGYTGDRCREECP--------VGRF--GQDCAETCDCAPDAR-CFP--------- 329
+C C GD C + CP G F +C E C+C A C+
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC-EACNCHGKAEECYYDENVARRNL 364
Query: 330 ---------ANGACL-CEHGFTGDRCTDRLCPDGFY---GLS------CQAPCTCDREHS 370
G C+ C G C C DGF+ G+S CQ PC CD S
Sbjct: 365 SLNIRGKYIGGGVCINCTQNTAGINC--ETCTDGFFRPKGVSPNYPRPCQ-PCHCDPIGS 421
Query: 371 LS--C-----HPMNG----ECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQAT 419
L+ C H G C C G+ G+ C+
Sbjct: 422 LNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCD--------------------------- 454
Query: 420 SGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV 479
+CA GYTG PD NCS S P G C+CKE + G+CS
Sbjct: 455 ----RCARGYTG-------YPDCKACNCSGLGSKNE----DPCFGPCICKENVEGGDCS- 498
Query: 480 PCPPGTWGFSCNASCQCAHEAVCSPQTGAC 509
C G + + C E CS + C
Sbjct: 499 RCKSGFFNLQEDNWKGC-DECFCSGVSNRC 527
Score = 47.0 bits (110), Expect = 9e-05
Identities = 60/231 (25%), Positives = 74/231 (32%), Gaps = 67/231 (29%)
Query: 423 CQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP 482
C C GY+G C + C P Y + S P G CV
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLR-----SQPGGRTPGPTLGTCV--------------- 1418
Query: 483 PGTWGFSCNASCQC-AHEAVCSPQTGAC-TCTPGWHGAHCQLPCPKGQFGEGCASRCDCD 540
CQC H ++C P+T C C G C+ C G +G DC
Sbjct: 1419 ----------PCQCNGHSSLCDPETSICQNCQHHTAGDFCER-CALGYYGIVKGLPNDCQ 1467
Query: 541 H-----------------SDGCDPVHGRCQ-CQAGWMGARCHLSCP-----EGLWGVNCS 577
++G D RC C G+ G C P G G +C
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLDDY--RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ 1525
Query: 578 NTCTCKNGGT----CLPENGNCVCAPGFRGPSCQRSCQ--PGRYGKRCVPC 622
C C G+ C P G C C PG G C C+ R G CV C
Sbjct: 1526 E-CECDPYGSLPVPCDPVTGFCTCRPGATGRKCD-GCKHWHAREGWECVFC 1574
Score = 46.2 bits (108), Expect = 2e-04
Identities = 61/260 (23%), Positives = 87/260 (33%), Gaps = 53/260 (20%)
Query: 106 AQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCG---NNSSCDPKSGV 162
A+ C ++C+C GD C +C PG KP G + C+
Sbjct: 293 ARACPLDPATNKSRCECEHNTCGDSC-DQCCPGFH----QKPWRAGTFLTKTECE----A 343
Query: 163 CSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQ 222
C+C + C + R + G G C + T ++C
Sbjct: 344 CNCHG--KAEECYYDENVARRNLSLNIRGKYIGG------GVCINCTQNT---AGINCET 392
Query: 223 GTSGFFCPSTHSCQNGGVFQTPQGSCSCPP-GWMGTIC---SLPCPEGFHGPNCSQECRC 278
T GFF P S + P C C P G + +C G +C C+
Sbjct: 393 CTDGFFRPKGVSPN----YPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC--HCKT 446
Query: 279 HNGGL-CDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCE 337
GG+ CD RCA GYTG + C G + C G C+C+
Sbjct: 447 GFGGVSCD------RCARGYTGYPDCKACNCSGLGSKNEDPC-----------FGPCICK 489
Query: 338 HGFTGDRCTDRLCPDGFYGL 357
G C+ C GF+ L
Sbjct: 490 ENVEGGDCS--RCKSGFFNL 507
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/287 (21%), Positives = 93/287 (32%), Gaps = 86/287 (29%)
Query: 462 IDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQ 521
+ G C+C G R + P P T + C+C H C C PG+H Q
Sbjct: 283 VGGMCICY-GHAR---ACPLDPAT----NKSRCECEHNT-CGDSCDQCC--PGFH----Q 327
Query: 522 LPCPKGQF---GEGCASRC-----DCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG 573
P G F E A C +C + + + + ++G ++C + G
Sbjct: 328 KPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAG 387
Query: 574 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQP------GRYGKRCVPCKCANH 627
+NC TC +G P P+ R CQP G + CV K H
Sbjct: 388 INCE---TCTDG----------FFRPKGVSPNYPRPCQPCHCDPIGSLNEVCV--KDEKH 432
Query: 628 SFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWT 687
+ + G+C+C G+ G C + C G+T
Sbjct: 433 ARRGLAPGSCHCKTGFGGVSCDR-------------------------------CARGYT 461
Query: 688 GHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPC 734
G+ + C G+ PC G C+C G C
Sbjct: 462 GYPDCKACNCSGLGSKNEDPC-----------FGPCICKENVEGGDC 497
Score = 43.9 bits (102), Expect = 8e-04
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
Query: 80 VKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRC-VAPNQCQCVPGWRGDDCSSECAPG 138
V ++ + Q CH + G +C ++ H R +AP C C G+ G C CA G
Sbjct: 403 VSPNYPRPCQPCH--CDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSC-DRCARG 459
Query: 139 MWG-PQCDKPCSCG--NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYY 183
G P C K C+C + + DP G C C ++ +C + C G++
Sbjct: 460 YTGYPDC-KACNCSGLGSKNEDPCFGPCICKENVEGGDCSR-CKSGFF 505
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 163 bits (412), Expect = 9e-40
Identities = 143/488 (29%), Positives = 183/488 (37%), Gaps = 111/488 (22%)
Query: 120 CQCVPGWRGDDCSSECAPG-------MWGPQCDKPCSC-GNNSSCDPKSGVC-SCPSGLQ 170
CQC PG+ G C S C P ++G C+ PC C G+ SCD +G C +C
Sbjct: 724 CQCPPGYTGSSCES-CWPRHRRVNGTIFGGICE-PCQCFGHAESCDDVTGECLNCKDHTG 781
Query: 171 PPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP 230
P C C PG+YG + + C P P+ P+C + S G C
Sbjct: 782 GPYC-DKCLPGFYGEPTKGTSE----DCQPCACPLNIPSNNFSPTCHLDRSLG---LICD 833
Query: 231 STHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP-----NCSQECRCHNG---- 281
CP G+ G C C EG+ G Q C+C++
Sbjct: 834 G------------------CPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFS 874
Query: 282 --GLCDRFTGQCR-CAPGYTGDRCREECPVGRFGQDCAETCDCAP---------DARCFP 329
G CD +G C C PG TG C E C G FG D + +C P C
Sbjct: 875 IPGSCDSLSGSCLICKPGTTGRYC-ELCADGYFG-DAVDAKNCQPCRCNAGGSFSEVCHS 932
Query: 330 ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQ---APCTCDR--EHSLSCHPMNGECSCLP 384
G C C G RC C G +GL PC C+ S C +G+C C P
Sbjct: 933 QTGQCECRANVQGQRCDK--CKAGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQP 989
Query: 385 GWAGLHCNESCPQDTHG------PGCQEHCLCLH-GGVCQATSGLCQCAPGYTGPHCASL 437
G G + C + HG GC C C H G C +G C C P G C S
Sbjct: 990 GVTG----KKCDRCAHGYFNFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGEKC-SK 1043
Query: 438 CPPDTYGVNCSARCSCENAIACSPID-------GECVCKEGWQRGNCSVPCPPGTWGFSC 490
C P+T+G + + C N +D G+C C + C+ C G W +
Sbjct: 1044 CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCT-ECSRGHWNYPR 1102
Query: 491 NASCQC-------------AHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG------E 531
C C + CS QTG CTC G HC C G+FG
Sbjct: 1103 CNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPL 1161
Query: 532 GCASRCDC 539
GC+S C C
Sbjct: 1162 GCSS-CYC 1168
Score = 163 bits (412), Expect = 9e-40
Identities = 143/487 (29%), Positives = 183/487 (37%), Gaps = 114/487 (23%)
Query: 291 CRCAPGYTGDRCREECPVGR------FGQDCAETCDCAPDAR-CFPANGACLCEHGFTGD 343
C+C PGYTG C P R FG C E C C A C G CL TG
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDHTGG 782
Query: 344 RCTDRLCPDGFYGL-------SCQAPCTC-----DREHSLSCHPMNGECSCLPGWAGLHC 391
D+ P GFYG CQ PC C S +CH L GL C
Sbjct: 783 PYCDKCLP-GFYGEPTKGTSEDCQ-PCACPLNIPSNNFSPTCH--------LDRSLGLIC 832
Query: 392 NESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARC 451
+ CP GP C+ +CA GY G P G +C C
Sbjct: 833 -DGCPVGYTGPRCE------------------RCAEGYFGQ-------PSVPGGSCQP-C 865
Query: 452 SCENAI------ACSPIDGEC-VCKEGWQRGNCSVPCPPGTWGFSCNAS----CQC---- 496
C + + +C + G C +CK G C + C G +G + +A C+C
Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL-CADGYFGDAVDAKNCQPCRCNAGG 924
Query: 497 AHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG----EGCASRCDCDH----SDGCDPV 548
+ VC QTG C C G C C G FG GC C+C+ S C+
Sbjct: 925 SFSEVCHSQTGQCECRANVQGQRCD-KCKAGTFGLQSARGCVP-CNCNSFGSKSFDCEE- 981
Query: 549 HGRCQCQAGWMGARCHLSCPEGLWGVN---CSNTCTCKN-GGTCLPENGNCVCAPGFRGP 604
G+C CQ G G +C C G + C+ C C + G C P+ G C+C P G
Sbjct: 982 SGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCT-ACECSHLGNNCDPKTGRCICPPNTIGE 1039
Query: 605 SCQRSCQPGRYGKR----CVPCKCANHSF----CHPSNGTCYCLAGWTGPDCSQPCPPGH 656
C + C P +G C C C+ C+ + G C C ++G C++ C GH
Sbjct: 1040 KCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGH 1097
Query: 657 WGENCAQTCQCHHGGT-------------CHPQDGSCICPLGWTGHHCLEGCPLGTFGAN 703
W C C GT C Q G C C + G HC + C G FG +
Sbjct: 1098 WNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHC-DRCRPGKFGLD 1156
Query: 704 CSQPCQC 710
P C
Sbjct: 1157 AKNPLGC 1163
Score = 147 bits (370), Expect = 7e-35
Identities = 115/384 (29%), Positives = 158/384 (41%), Gaps = 71/384 (18%)
Query: 414 GVCQATSGLCQCAPGYTGPHCASLCPPDT------YGVNCSARCSC-ENAIACSPIDGEC 466
G A +CQC PGYTG C S P +G C C C +A +C + GEC
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEP-CQCFGHAESCDDVTGEC 773
Query: 467 V-CKEGWQRGNCSVPCPPGTWGFSCNAS------CQCAHEAVCSPQTGACT--------- 510
+ CK+ C C PG +G + C C + + C
Sbjct: 774 LNCKDHTGGPYCD-KCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832
Query: 511 --CTPGWHGAHCQLPCPKGQFGE-----GCASRCDCDHS------DGCDPVHGRCQ-CQA 556
C G+ G C+ C +G FG+ G C C+ + CD + G C C+
Sbjct: 833 DGCPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP 891
Query: 557 GWMGARCHLSCPEGLWG-----VNCSNTCTCKNGGT----CLPENGNCVCAPGFRGPSCQ 607
G G C L C +G +G NC C C GG+ C + G C C +G C
Sbjct: 892 GTTGRYCEL-CADGYFGDAVDAKNCQ-PCRCNAGGSFSEVCHSQTGQCECRANVQGQRCD 949
Query: 608 RSCQPGRYG----KRCVPCKC---ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWG-- 658
+ C+ G +G + CVPC C + SF +G C+C G TG C + C G++
Sbjct: 950 K-CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDR-CAHGYFNFQ 1007
Query: 659 ENCAQTCQCHH-GGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS---QPCQCGP-- 712
E C+C H G C P+ G CICP G C + C T+G + + + C C
Sbjct: 1008 EGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVG 1066
Query: 713 --GEKCHPETGACVCPPGHSGAPC 734
+C+ TG C C P SGA C
Sbjct: 1067 SLDFQCNVNTGQCNCHPKFSGAKC 1090
Score = 90.9 bits (224), Expect = 6e-18
Identities = 80/286 (27%), Positives = 104/286 (36%), Gaps = 68/286 (23%)
Query: 119 QCQCVPGWRGDDCSSECAPGMWGPQCDK---PCSC---GNNSSCDPKSGVCSCPSGLQPP 172
QC+C +G C +C G +G Q + PC+C G+ S +SG C C G+
Sbjct: 936 QCECRANVQGQRCD-KCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGK 994
Query: 173 NCLQPCTPGYY----GPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFF 228
C C GY+ G C G CDP+TG C CP G C C+ T G
Sbjct: 995 KC-DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCS-KCAPNTWG-- 1050
Query: 229 CPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFT 288
HS G +C+C T+ SL C+ T
Sbjct: 1051 ----HSITTG------CKACNC-----STVGSLDFQ-------------------CNVNT 1076
Query: 289 GQCRCAPGYTGDRCREECPVGRFGQDCAETCDC-------------APDARCFPANGACL 335
GQC C P ++G +C EC G + CDC C G C
Sbjct: 1077 GQCNCHPKFSGAKC-TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT 1135
Query: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECS 381
C+ G C DR C G +GL + P C S C +CS
Sbjct: 1136 CKVNVEGIHC-DR-CRPGKFGLDAKNPLGCS---SCYCFGTTTQCS 1176
Score = 79.0 bits (193), Expect = 2e-14
Identities = 64/207 (30%), Positives = 81/207 (39%), Gaps = 47/207 (22%)
Query: 571 LWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGR-------YGKRCVPCK 623
L VN + + G+ C C PG+ G SC+ SC P +G C PC+
Sbjct: 700 LSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCE-SCWPRHRRVNGTIFGGICEPCQ 758
Query: 624 CANHS-FCHPSNGTCYCLAGWTGPDCSQPCPPGHWGE------NCAQTCQC-------HH 669
C H+ C G C TG C PG +GE Q C C +
Sbjct: 759 CFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNF 818
Query: 670 GGTCHPQ-------DGSCICPLGWTGHHCLEGCPLGTFG-----ANCSQPCQCG------ 711
TCH DG CP+G+TG C E C G FG QPCQC
Sbjct: 819 SPTCHLDRSLGLICDG---CPVGYTGPRC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFS 874
Query: 712 -PGEKCHPETGAC-VCPPGHSGAPCRI 736
PG C +G+C +C PG +G C +
Sbjct: 875 IPG-SCDSLSGSCLICKPGTTGRYCEL 900
Score = 77.0 bits (188), Expect = 8e-14
Identities = 55/180 (30%), Positives = 70/180 (38%), Gaps = 42/180 (23%)
Query: 595 CVCAPGFRGPSCQRSCQPGRYGKR--------------CVPCKCANHS-FCHPSNGTCYC 639
C C G+ G SC+ +C PG Y R CVPC+C HS C P C
Sbjct: 1380 CDCPLGYSGLSCE-ACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 640 LAGWTGPDCSQPCPPGHWG-----ENCAQTCQCHHGGTCHPQDGSCI-----------CP 683
T D + C G++G N Q C C + + SC+ CP
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 684 LGWTGHHCLEGCP-----LGTFGANCSQPCQCGPGEK----CHPETGACVCPPGHSGAPC 734
G+ G +C P G G +C Q C+C P C P TG C C PG +G C
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSC-QECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Score = 72.8 bits (177), Expect = 2e-12
Identities = 76/285 (26%), Positives = 111/285 (38%), Gaps = 67/285 (23%)
Query: 53 EPCERPWEGPHTCPQPTVVYRTVYRQ----VVKTDHRQRLQCCHGFY--ESRGFCVPLCA 106
E E+ W+ P+ V+RTV R+ ++ H ++ +G + +SR + +
Sbjct: 1305 EMTEKEWKYYGDDPR---VHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEV 1361
Query: 107 QECVHGRCVAP-----NQCQCVPGWRGDDCSSECAPGMW-----------GPQCDK--PC 148
E G + P +C C G+ G C + C PG + GP PC
Sbjct: 1362 AEQGRGTTMTPPADLIEKCDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPC 1420
Query: 149 SC-GNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFC 207
C G++S CDP++ +C + + C GYYG G P D Q C C
Sbjct: 1421 QCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIV-------KGLPNDCQQ--CAC 1471
Query: 208 PAERTGPSCDVSC-SQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCP-- 264
P + + SC ++G + C + CP G+ G C P
Sbjct: 1472 PLISSSNNFSPSCVAEGLDDYRCTA------------------CPRGYEGQYCERCAPGY 1513
Query: 265 ---EGFHGPNCSQECRCHNGGL----CDRFTGQCRCAPGYTGDRC 302
G G +C QEC C G CD TG C C PG TG +C
Sbjct: 1514 TGSPGNPGGSC-QECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Score = 69.7 bits (169), Expect = 1e-11
Identities = 73/239 (30%), Positives = 87/239 (36%), Gaps = 69/239 (28%)
Query: 163 CSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPS--CDVSC 220
C CP G +C + C PG+Y + R Q G P G C P + G S CD
Sbjct: 1380 CDCPLGYSGLSC-EACLPGFY----RLRSQPGGRTPGPTLGTCV-PCQCNGHSSLCD--- 1430
Query: 221 SQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG-----PNCSQE 275
P T CQN C G C C G++G PN Q+
Sbjct: 1431 ---------PETSICQN------------CQHHTAGDFCER-CALGYYGIVKGLPNDCQQ 1468
Query: 276 CRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACL 335
C C + F+ C A G RC CP G GQ C CAP
Sbjct: 1469 CACPLISSSNNFSPSC-VAEGLDDYRCTA-CPRGYEGQYCER---CAP------------ 1511
Query: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS--CHPMNGECSCLPGWAGLHCN 392
G+TG G G SCQ C CD SL C P+ G C+C PG G C+
Sbjct: 1512 ---GYTGS--------PGNPGGSCQE-CECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 60.1 bits (144), Expect = 1e-08
Identities = 65/252 (25%), Positives = 81/252 (32%), Gaps = 77/252 (30%)
Query: 350 CPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGP--GCQEH 407
CP G+ GLSC+A CLPG+ L T GP G
Sbjct: 1382 CPLGYSGLSCEA--------------------CLPGFYRLRSQPG--GRTPGPTLGTCVP 1419
Query: 408 CLCL-HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGV-----NCSARCSCENAIACSP 461
C C H +C + +CQ +T C YG+ N +C+C + +
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNN 1479
Query: 462 IDGECV-----------CKEGWQRGNCSVPCP-----PGTWGFSCNASCQC----AHEAV 501
CV C G++ C P PG G SC C+C +
Sbjct: 1480 FSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ-ECECDPYGSLPVP 1538
Query: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
C P TG CTC PG G C DGC H R GW
Sbjct: 1539 CDPVTGFCTCRPGATGRKC----------------------DGCKHWHAR----EGWECV 1572
Query: 562 RCHLSCPEGLWG 573
C C L G
Sbjct: 1573 FCGDECTGLLLG 1584
Score = 54.3 bits (129), Expect = 6e-07
Identities = 55/170 (32%), Positives = 66/170 (38%), Gaps = 47/170 (27%)
Query: 90 CCHGFYESR------------GFCVPLCAQECVHGRCVAPNQ--CQ-CVPGWRGDDCSSE 134
C GFY R G CVP Q H P CQ C GD C
Sbjct: 1394 CLPGFYRLRSQPGGRTPGPTLGTCVP--CQCNGHSSLCDPETSICQNCQHHTAGDFCE-R 1450
Query: 135 CAPGMWG-----PQCDKPCSCGNNSSCDPKSGVC-----------SCPSGLQPPNCLQPC 178
CA G +G P + C+C SS + S C +CP G + C + C
Sbjct: 1451 CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYC-ERC 1509
Query: 179 TPGYYGP------ACQFRCQC--HGA---PCDPQTGACFCPAERTGPSCD 217
PGY G +CQ C+C +G+ PCDP TG C C TG CD
Sbjct: 1510 APGYTGSPGNPGGSCQ-ECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 49.7 bits (117), Expect = 1e-05
Identities = 70/270 (25%), Positives = 89/270 (32%), Gaps = 98/270 (36%)
Query: 290 QCRCAPGYTGDRCREECP--------VGRF--GQDCAETCDCAPDAR-CFP--------- 329
+C C GD C + CP G F +C E C+C A C+
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC-EACNCHGKAEECYYDENVARRNL 364
Query: 330 ---------ANGACL-CEHGFTGDRCTDRLCPDGFY---GLS------CQAPCTCDREHS 370
G C+ C G C C DGF+ G+S CQ PC CD S
Sbjct: 365 SLNIRGKYIGGGVCINCTQNTAGINC--ETCTDGFFRPKGVSPNYPRPCQ-PCHCDPIGS 421
Query: 371 LS--C-----HPMNG----ECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQAT 419
L+ C H G C C G+ G+ C+
Sbjct: 422 LNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCD--------------------------- 454
Query: 420 SGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV 479
+CA GYTG PD NCS S P G C+CKE + G+CS
Sbjct: 455 ----RCARGYTG-------YPDCKACNCSGLGSKNE----DPCFGPCICKENVEGGDCS- 498
Query: 480 PCPPGTWGFSCNASCQCAHEAVCSPQTGAC 509
C G + + C E CS + C
Sbjct: 499 RCKSGFFNLQEDNWKGC-DECFCSGVSNRC 527
Score = 47.0 bits (110), Expect = 9e-05
Identities = 60/231 (25%), Positives = 74/231 (32%), Gaps = 67/231 (29%)
Query: 423 CQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP 482
C C GY+G C + C P Y + S P G CV
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLR-----SQPGGRTPGPTLGTCV--------------- 1418
Query: 483 PGTWGFSCNASCQC-AHEAVCSPQTGAC-TCTPGWHGAHCQLPCPKGQFGEGCASRCDCD 540
CQC H ++C P+T C C G C+ C G +G DC
Sbjct: 1419 ----------PCQCNGHSSLCDPETSICQNCQHHTAGDFCER-CALGYYGIVKGLPNDCQ 1467
Query: 541 H-----------------SDGCDPVHGRCQ-CQAGWMGARCHLSCP-----EGLWGVNCS 577
++G D RC C G+ G C P G G +C
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLDDY--RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ 1525
Query: 578 NTCTCKNGGT----CLPENGNCVCAPGFRGPSCQRSCQ--PGRYGKRCVPC 622
C C G+ C P G C C PG G C C+ R G CV C
Sbjct: 1526 E-CECDPYGSLPVPCDPVTGFCTCRPGATGRKCD-GCKHWHAREGWECVFC 1574
Score = 46.2 bits (108), Expect = 2e-04
Identities = 61/260 (23%), Positives = 87/260 (33%), Gaps = 53/260 (20%)
Query: 106 AQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCG---NNSSCDPKSGV 162
A+ C ++C+C GD C +C PG KP G + C+
Sbjct: 293 ARACPLDPATNKSRCECEHNTCGDSC-DQCCPGFH----QKPWRAGTFLTKTECE----A 343
Query: 163 CSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQ 222
C+C + C + R + G G C + T ++C
Sbjct: 344 CNCHG--KAEECYYDENVARRNLSLNIRGKYIGG------GVCINCTQNT---AGINCET 392
Query: 223 GTSGFFCPSTHSCQNGGVFQTPQGSCSCPP-GWMGTIC---SLPCPEGFHGPNCSQECRC 278
T GFF P S + P C C P G + +C G +C C+
Sbjct: 393 CTDGFFRPKGVSPN----YPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC--HCKT 446
Query: 279 HNGGL-CDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCE 337
GG+ CD RCA GYTG + C G + C G C+C+
Sbjct: 447 GFGGVSCD------RCARGYTGYPDCKACNCSGLGSKNEDPC-----------FGPCICK 489
Query: 338 HGFTGDRCTDRLCPDGFYGL 357
G C+ C GF+ L
Sbjct: 490 ENVEGGDCS--RCKSGFFNL 507
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/287 (21%), Positives = 93/287 (32%), Gaps = 86/287 (29%)
Query: 462 IDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQ 521
+ G C+C G R + P P T + C+C H C C PG+H Q
Sbjct: 283 VGGMCICY-GHAR---ACPLDPAT----NKSRCECEHNT-CGDSCDQCC--PGFH----Q 327
Query: 522 LPCPKGQF---GEGCASRC-----DCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG 573
P G F E A C +C + + + + ++G ++C + G
Sbjct: 328 KPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAG 387
Query: 574 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQP------GRYGKRCVPCKCANH 627
+NC TC +G P P+ R CQP G + CV K H
Sbjct: 388 INCE---TCTDG----------FFRPKGVSPNYPRPCQPCHCDPIGSLNEVCV--KDEKH 432
Query: 628 SFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWT 687
+ + G+C+C G+ G C + C G+T
Sbjct: 433 ARRGLAPGSCHCKTGFGGVSCDR-------------------------------CARGYT 461
Query: 688 GHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPC 734
G+ + C G+ PC G C+C G C
Sbjct: 462 GYPDCKACNCSGLGSKNEDPC-----------FGPCICKENVEGGDC 497
Score = 43.9 bits (102), Expect = 8e-04
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
Query: 80 VKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRC-VAPNQCQCVPGWRGDDCSSECAPG 138
V ++ + Q CH + G +C ++ H R +AP C C G+ G C CA G
Sbjct: 403 VSPNYPRPCQPCH--CDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSC-DRCARG 459
Query: 139 MWG-PQCDKPCSCG--NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYY 183
G P C K C+C + + DP G C C ++ +C + C G++
Sbjct: 460 YTGYPDC-KACNCSGLGSKNEDPCFGPCICKENVEGGDCSR-CKSGFF 505
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 162 bits (409), Expect = 2e-39
Identities = 142/449 (31%), Positives = 177/449 (39%), Gaps = 88/449 (19%)
Query: 319 CDCAPD----ARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLS---CQAPCTCDREHSL 371
C C P + C P G CLC+ G G RC LC G+YG CQA C C E +L
Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCD--LCAPGYYGFGPTGCQA-CQCSHEGAL 839
Query: 372 S--CHPMNGECSCLPGWAGLHCNESCPQDTHG-PGCQEHCLCL-HGGVCQATSGLCQCAP 427
S C +G+C C G GL C + C + G P C+ C+C H C +G C
Sbjct: 840 SSLCEKTSGQCLCRTGAFGLRC-DRCQRGQWGFPSCRP-CVCNGHADECNTHTGACLGCR 897
Query: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWG 487
+TG CE IA G+ G Q C PCP G G
Sbjct: 898 DHTGGE------------------HCERCIA--GFHGDPRLPYGGQCRPC--PCPEGP-G 934
Query: 488 FSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE-----GCASRCDCDHS 542
+ + C H+ S Q C C G+ G C+ C G FG+ G C+C +
Sbjct: 935 SQRHFATSC-HQDEYSQQI-VCHCRAGYTGLRCE-ACAPGHFGDPSRPGGRCQLCECSGN 991
Query: 543 ------DGCDPVHGRC-QCQAGWMGARCHLSCPEGLWGV---NCSNTCTCKNGGT----- 587
D CDP G+C +C G C C G G + CTC GT
Sbjct: 992 IDPMDPDACDPHTGQCLRCLHHTEGPHC-AHCKPGFHGQAARQSCHRCTCNLLGTNPQQC 1050
Query: 588 -------CLPENGNCVCAPGFRGPSCQRSCQPGRY----GKRCVPCKC----ANHSFCHP 632
C P +G C C P +GPSC R C P + G C PC C A C+
Sbjct: 1051 PSPDQCHCDPSSGQCPCLPNVQGPSCDR-CAPNFWNLTSGHGCQPCACHPSRARGPTCNE 1109
Query: 633 SNGTCYCLAGWTGPDCSQPCPPGHWGENCAQ--TCQCHHGG----TCHPQDGSCICPLGW 686
G C+C AG+ G CS+ C HWG+ Q C C G CH G C C G
Sbjct: 1110 FTGQCHCRAGFGGRTCSE-CQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGV 1168
Query: 687 TGHHCLEGCPLGTFGA-NCSQPCQCGPGE 714
+G C + C G G PC G+
Sbjct: 1169 SGVRC-DQCARGFSGIFPACHPCHACFGD 1196
Score = 155 bits (393), Expect = 1e-37
Identities = 124/389 (31%), Positives = 152/389 (39%), Gaps = 80/389 (20%)
Query: 416 CQATSGLCQCAPGYTGPHCASLCPPDTYG---VNCSA-RCSCENAIA--CSPIDGECVCK 469
C G C C PG G C LC P YG C A +CS E A++ C G+C+C+
Sbjct: 795 CNPHGGQCLCKPGVVGRRC-DLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCR 853
Query: 470 EGWQRGNCSVPCPPGTWGFSCNASCQC-AHEAVCSPQTGACT-------------CTPGW 515
G C C G WGF C C H C+ TGAC C G+
Sbjct: 854 TGAFGLRCD-RCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGF 912
Query: 516 HG-------AHCQ-LPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSC 567
HG C+ PCP+G G C + + C C+AG+ G RC +C
Sbjct: 913 HGDPRLPYGGQCRPCPCPEGP-GSQRHFATSCHQDEYSQQIV--CHCRAGYTGLRCE-AC 968
Query: 568 PEGLWG-----------VNCSNTCTCKNGGTCLPENGNCV-CAPGFRGPSCQRSCQPGRY 615
G +G CS + C P G C+ C GP C C+PG +
Sbjct: 969 APGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAH-CKPGFH 1027
Query: 616 GK-------RCV-------PCKCANHSFCH--PSNGTCYCLAGWTGPDCSQPCPPGHW-- 657
G+ RC P +C + CH PS+G C CL GP C + C P W
Sbjct: 1028 GQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDR-CAPNFWNL 1086
Query: 658 --GENCAQTCQCH----HGGTCHPQDGSCICPLGWTGHHCLEGCPL--GTFGANCSQPCQ 709
G C Q C CH G TC+ G C C G+ G C E L G G C C
Sbjct: 1087 TSGHGC-QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC-HACD 1144
Query: 710 CGPG----EKCHPETGACVCPPGHSGAPC 734
C +CH TG C C PG SG C
Sbjct: 1145 CDSRGIDTPQCHRFTGHCSCRPGVSGVRC 1173
Score = 148 bits (373), Expect = 3e-35
Identities = 130/428 (30%), Positives = 167/428 (39%), Gaps = 88/428 (20%)
Query: 246 GSCSCPPGWMGTICSLPCPEGFH--GPNCSQECRCHNGG----LCDRFTGQCRCAPGYTG 299
G C C PG +G C L C G++ GP Q C+C + G LC++ +GQC C G G
Sbjct: 800 GQCLCKPGVVGRRCDL-CAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFG 858
Query: 300 DRCREECPVGRFGQDCAETCDCAPDA-RCFPANGACL-CEHGFTGDRCTDRLCPDGFYGL 357
RC + C G++G C C A C GACL C G+ C C GF+G
Sbjct: 859 LRC-DRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHC--ERCIAGFHG- 914
Query: 358 SCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQ 417
+ L P G+C P CP+ GPG Q H
Sbjct: 915 ----------DPRL---PYGGQCRPCP----------CPE---GPGSQRHFATSCHQDEY 948
Query: 418 ATSGLCQCAPGYTGPHCASLCP-----PDTYGVNCSARCSCENAI------ACSPIDGEC 466
+ +C C GYTG C + P P G C C C I AC P G+C
Sbjct: 949 SQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQL-CECSGNIDPMDPDACDPHTGQC 1007
Query: 467 V-CKEGWQRGNCSVPCPPGTWGFSCNASC-------------QC--AHEAVCSPQTGACT 510
+ C + +C+ C PG G + SC QC + C P +G C
Sbjct: 1008 LRCLHHTEGPHCA-HCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCP 1066
Query: 511 CTPGWHGAHCQLPCPKG---QFGEGCASRCDCDHSDG----CDPVHGRCQCQAGWMGARC 563
C P G C P G GC C C S C+ G+C C+AG+ G C
Sbjct: 1067 CLPNVQGPSCDRCAPNFWNLTSGHGC-QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTC 1125
Query: 564 HLSCPEGLW---GVNCSNTCTCKNGGTCLPE----NGNCVCAPGFRGPSCQRSCQPGRYG 616
C E W G+ C + C C + G P+ G+C C PG G C + C G G
Sbjct: 1126 S-ECQELHWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ-CARGFSG 1182
Query: 617 --KRCVPC 622
C PC
Sbjct: 1183 IFPACHPC 1190
Score = 140 bits (353), Expect = 6e-33
Identities = 132/431 (30%), Positives = 166/431 (38%), Gaps = 91/431 (21%)
Query: 119 QCQCVPGWRGDDCSSECAPGMWG--PQCDKPCSCGN----NSSCDPKSGVCSCPSGLQPP 172
QC C PG G C CAPG +G P + C C + +S C+ SG C C +G
Sbjct: 801 QCLCKPGVVGRRCDL-CAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGL 859
Query: 173 NCLQPCTPGYYG-PACQFRCQC--HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFC 229
C C G +G P+C+ C C H C+ TGAC + TG C + +GF
Sbjct: 860 RC-DRCQRGQWGFPSCR-PCVCNGHADECNTHTGACLGCRDHTGGE---HCERCIAGFH- 913
Query: 230 PSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTG 289
G + P G C P PCPEG G CH D ++
Sbjct: 914 ---------GDPRLPYGG-QCRP--------CPCPEG-PGSQRHFATSCHQ----DEYSQ 950
Query: 290 Q--CRCAPGYTGDRCREECPVGRFGQDC-----AETCDCA-------PDARCFPANGACL 335
Q C C GYTG RC E C G FG + C+C+ PDA C P G CL
Sbjct: 951 QIVCHCRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDA-CDPHTGQCL 1008
Query: 336 -CEHGFTGDRCTDRLCPDGFYGLSCQAPC-------------TCDREHSLSCHPMNGECS 381
C H G C C GF+G + + C C C P +G+C
Sbjct: 1009 RCLHHTEGPHCAH--CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCP 1066
Query: 382 CLPGWAGLHCNESCPQD---THGPGCQEHCLC----LHGGVCQATSGLCQCAPGYTGPHC 434
CLP G C+ P T G GCQ C C G C +G C C G+ G C
Sbjct: 1067 CLPNVQGPSCDRCAPNFWNLTSGHGCQP-CACHPSRARGPTCNEFTGQCHCRAGFGGRTC 1125
Query: 435 ASLCPPDTY---GVNCSARCSCE----NAIACSPIDGECVCKEGWQRGNCSVPCPPGTWG 487
S C + G+ C A C C+ + C G C C+ G C C G G
Sbjct: 1126 -SECQELHWGDPGLQCHA-CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCD-QCARGFSG 1182
Query: 488 F--SCNASCQC 496
+C+ C
Sbjct: 1183 IFPACHPCHAC 1193
Score = 120 bits (301), Expect = 7e-27
Identities = 90/298 (30%), Positives = 114/298 (38%), Gaps = 52/298 (17%)
Query: 490 CNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG---EGCASRCDCDH----S 542
C + Q + + C+P G C C PG G C L C G +G GC + C C H S
Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGCQA-CQCSHEGALS 840
Query: 543 DGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCK-NGGTCLPENGNCV-CAPG 600
C+ G+C C+ G G RC C G WG C C + C G C+ C
Sbjct: 841 SLCEKTSGQCLCRTGAFGLRCD-RCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDH 899
Query: 601 FRGPSCQRSCQPG-------RYGKRCVPCKCANH--------SFCHPSNGT----CYCLA 641
G C+R C G YG +C PC C + CH + C+C A
Sbjct: 900 TGGEHCER-CIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
Query: 642 GWTGPDCSQPCPPGHWGENC-----AQTCQCHHG------GTCHPQDGSCICPLGWT-GH 689
G+TG C + C PGH+G+ Q C+C C P G C+ L T G
Sbjct: 959 GYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
Query: 690 HCLEGCPLGTFGANCSQPCQ------CGPGEKCHPETGACVCPPGHSGAPCRIGIQEP 741
HC C G G Q C G + P C C P PC +Q P
Sbjct: 1018 HCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGP 1074
Score = 99.0 bits (245), Expect = 2e-20
Identities = 85/255 (33%), Positives = 105/255 (41%), Gaps = 60/255 (23%)
Query: 120 CQCVPGWRGDDCSSECAPGMWGPQCDKP------CSCGNN------SSCDPKSGVC-SCP 166
C C G+ G C + CAPG +G +P C C N +CDP +G C C
Sbjct: 954 CHCRAGYTGLRCEA-CAPGHFGDP-SRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
Query: 167 SGLQPPNCLQPCTPGYYGPACQFRC-------------------QCHGAPCDPQTGACFC 207
+ P+C C PG++G A + C QCH CDP +G C C
Sbjct: 1012 HHTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCH---CDPSSGQCPC 1067
Query: 208 PAERTGPSCDVSCSQG----TSGFFCP--STH-SCQNGGVFQTPQGSCSCPPGWMGTICS 260
GPSCD C+ TSG C + H S G G C C G+ G CS
Sbjct: 1068 LPNVQGPSCD-RCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS 1126
Query: 261 LPCPE---GFHGPNCSQECRCHNGGL----CDRFTGQCRCAPGYTGDRCREECPVGRFGQ 313
C E G G C C C + G+ C RFTG C C PG +G RC ++C G G
Sbjct: 1127 -ECQELHWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRC-DQCARGFSGI 1183
Query: 314 DCAETCDCAPDARCF 328
A C P CF
Sbjct: 1184 FPA----CHPCHACF 1194
Score = 75.1 bits (183), Expect = 3e-13
Identities = 72/255 (28%), Positives = 92/255 (36%), Gaps = 66/255 (25%)
Query: 462 IDGECVCKEGWQRGNCS--------VPCPPGTWGFS--CNASCQC-AHEAVC-------- 502
+ G C+CK + NC +P P G S C C+C H C
Sbjct: 306 VHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACR-KCECHGHTHSCHFDMAVYL 364
Query: 503 ---SPQTGACT-CTPGWHGAHCQLPCP-------KGQFGEGCASRCDCD---HSDG--CD 546
+ G C C G HC+L P K CDCD DG CD
Sbjct: 365 ASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCD 424
Query: 547 P--------VHGRCQCQAGWMGARCHLSCPEGLWGVNCSN-----TCTCKNGGT------ 587
V G+C+C+ +G RC C +G +G++ S+ C C GT
Sbjct: 425 SHDDPALGLVSGQCRCKEHVVGTRCQ-QCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP 483
Query: 588 CLPENGNCVCAPGFRGPSCQRSCQPGRYGKR-----CVPCKC----ANHSFCHPSNGTCY 638
C P +G+C C G C R C PG +G C PC C A C G C+
Sbjct: 484 CDPNSGSCYCKRLVTGRGCDR-CLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCH 542
Query: 639 CLAGWTGPDCSQPCP 653
C G C Q P
Sbjct: 543 CRQHMVGRRCEQVQP 557
Score = 69.7 bits (169), Expect = 1e-11
Identities = 77/281 (27%), Positives = 100/281 (35%), Gaps = 50/281 (17%)
Query: 316 AETCDCAPDARCFP---ANGACLCEHGFTG---DRCTD-------RLCPDGFYGLSCQAP 362
A C AP A +GAC+C+H G ++C D R DG + +C+
Sbjct: 289 ASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDG-HSHACRK- 346
Query: 363 CTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGL 422
C C H+ SCH +G C + C +T G C+ LC T L
Sbjct: 347 CEC-HGHTHSCHFDMAVYLASGNVSGGVC-DGCQHNTAGRHCE---LCRPFFYRDPTKDL 401
Query: 423 CQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP 482
P C D G RC + A + G+C CKE C C
Sbjct: 402 -------RDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQ-QCR 453
Query: 483 PGTWGFS-----------CNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG- 530
G +G S CNA C P +G+C C G C C G +G
Sbjct: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD-RCLPGHWGL 512
Query: 531 ----EGCASRCDCDHSDG----CDPVHGRCQCQAGWMGARC 563
GC CDCD CD G+C C+ +G RC
Sbjct: 513 SHDLLGCRP-CDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
Score = 64.3 bits (155), Expect = 6e-10
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 35/150 (23%)
Query: 113 RCVAPNQCQ---------CVPGWRGDDCSSECAPGMW----GPQCDKPCSC----GNNSS 155
+C +P+QC C+P +G C CAP W G C +PC+C +
Sbjct: 1049 QCPSPDQCHCDPSSGQCPCLPNVQGPSC-DRCAPNFWNLTSGHGC-QPCACHPSRARGPT 1106
Query: 156 CDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCD------PQ----TGAC 205
C+ +G C C +G C + C ++G QCH CD PQ TG C
Sbjct: 1107 CNEFTGQCHCRAGFGGRTCSE-CQELHWGDP---GLQCHACDCDSRGIDTPQCHRFTGHC 1162
Query: 206 FCPAERTGPSCDVSCSQGTSGFFCPSTHSC 235
C +G CD C++G SG F P+ H C
Sbjct: 1163 SCRPGVSGVRCD-QCARGFSGIF-PACHPC 1190
Score = 58.5 bits (140), Expect = 3e-08
Identities = 51/193 (26%), Positives = 66/193 (34%), Gaps = 61/193 (31%)
Query: 132 SSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPA----- 186
S +C P G Q C ++ + SG C C + C Q C G++G +
Sbjct: 409 SCDCDP--MGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRC-QQCRDGFFGLSISDRL 465
Query: 187 -CQFRCQCHG-------APCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNG 238
C+ RCQC+ PCDP +G+C+C TG CD
Sbjct: 466 GCR-RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD--------------------- 503
Query: 239 GVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGL----CDRFTGQCRCA 294
C PG G H + C C GG CD TGQC C
Sbjct: 504 ----------RCLPGHWGLS---------HDLLGCRPCDCDVGGALDPQCDEGTGQCHCR 544
Query: 295 PGYTGDRCREECP 307
G RC + P
Sbjct: 545 QHMVGRRCEQVQP 557
Score = 57.4 bits (137), Expect = 7e-08
Identities = 74/300 (24%), Positives = 96/300 (32%), Gaps = 78/300 (26%)
Query: 191 CQCHGAPCDPQTGACFCPAERTGPSCDVS-CSQGTSGFFCPSTHSCQNGGVFQTPQGSCS 249
C H + C P GA PA G C T G C CQ+
Sbjct: 285 CYGHASECAPAPGA---PAHAEGMVHGACICKHNTRGLNC---EQCQD------------ 326
Query: 250 CPPGWMGTICSLPCPEGFHGPNCSQECRCH-------------------NGGLCD----R 286
+ + P +G H C ++C CH +GG+CD
Sbjct: 327 ----FYRDLPWRPAEDG-HSHAC-RKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHN 380
Query: 287 FTGQ-CR-CAPGYTGDRCRE--------ECPVGRFGQDCAETCDCAPDARCFPANGACLC 336
G+ C C P + D ++ C G CD D +G C C
Sbjct: 381 TAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRC 440
Query: 337 EHGFTGDRCTDRLCPDGFYGLS---------CQAPCTCDREHSLSCHPMNGECSCLPGWA 387
+ G RC C DGF+GLS CQ S C P +G C C
Sbjct: 441 KEHVVGTRCQQ--CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVT 498
Query: 388 GLHCNESCPQD---THG-PGCQEHCLCLHGGV----CQATSGLCQCAPGYTGPHCASLCP 439
G C+ P +H GC+ C C GG C +G C C G C + P
Sbjct: 499 GRGCDRCLPGHWGLSHDLLGCRP-CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQP 557
Score = 56.2 bits (134), Expect = 2e-07
Identities = 74/295 (25%), Positives = 100/295 (33%), Gaps = 77/295 (26%)
Query: 493 SCQC-AHEAVCSPQTGA-----------CTCTPGWHGAHCQ--------LPCPKGQFGEG 532
+C C H + C+P GA C C G +C+ LP + G
Sbjct: 282 NCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
Query: 533 CASR-CDCD-HSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLP 590
A R C+C H+ C G C C G +C
Sbjct: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCD-GCQHNTAGRHCE------------- 387
Query: 591 ENGNCVCAPGF--------RGPSCQRSCQPGRYGKRCVPCKCANHSFCHPS----NGTCY 638
+C P F R P+ RSC G + +C +H P+ +G C
Sbjct: 388 -----LCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGG-RCDSHD--DPALGLVSGQCR 439
Query: 639 CLAGWTGPDCSQPCPPGHWGENCA-----QTCQCHHGGT------CHPQDGSCICPLGWT 687
C G C Q C G +G + + + CQC+ GT C P GSC C T
Sbjct: 440 CKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVT 498
Query: 688 GHHCLEGCPLGTFGANCS----QPCQCGPG----EKCHPETGACVCPPGHSGAPC 734
G C + C G +G + +PC C G +C TG C C G C
Sbjct: 499 GRGC-DRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
Score = 37.7 bits (86), Expect = 0.057
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
Query: 697 LGTFGANCSQPCQCGP----GEKCHPETGACVCPPGHSGAPC 734
L T N + PCQC P +C+P G C+C PG G C
Sbjct: 772 LSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRC 813
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 155 bits (392), Expect = 2e-37
Identities = 141/462 (30%), Positives = 176/462 (38%), Gaps = 95/462 (20%)
Query: 248 CSCPPGWMGTICSLPCPEGFH-------GPNCSQECRCHNGGLCDRFTGQC-RCAPGYTG 299
C CP G+ GT C C G++ G C Q C CH G C CA TG
Sbjct: 709 CECPQGYTGTSCE-SCLSGYYRVDGILFGGIC-QPCECHGHAAECNVHGVCIACAHNTTG 766
Query: 300 DRCREECPVGRFGQDCAETC-DCAPDA------------RCFPANG---AC-LCEHGFTG 342
C E+C G +G+ T DC P A C +G C C G++G
Sbjct: 767 VHC-EQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSG 825
Query: 343 DRCTDRLCPDGFYGL------SCQAPCTC----DREHSLSCHPMNGEC-SCLPGWAGLHC 391
C C DG+YG SC PC C D + C + GEC CL G HC
Sbjct: 826 AWC--ERCADGYYGNPTVPGESC-VPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882
Query: 392 NESCPQDTHGPG--------CQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTY 443
E C +G C+ H H VC +GLC C P TG C C Y
Sbjct: 883 -ERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQC-DQCLHGYY 940
Query: 444 GVNCSARC-SCENAIACSPID-----GECVCKEGWQRGNCSVPCPPGTWGF---SCNASC 494
G++ C C ++A S D G+C C G C C G + + SC C
Sbjct: 941 GLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RCAHGFYAYQDGSC-TPC 998
Query: 495 QCAH-EAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG----EGCASRCDC----DHSDGC 545
C H + C P+TG C C P G C+ C G +G GC + C+C C
Sbjct: 999 DCPHTQNTCDPETGECVCPPHTQGVKCE-ECEDGHWGYDAEVGCQA-CNCSLVGSTHHRC 1056
Query: 546 DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGT-------------CLPEN 592
D V G CQC++ + G C C G C C GT C+ E
Sbjct: 1057 DVVTGHCQCKSKFGGRACD-QCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEET 1115
Query: 593 GNCVCAPGFRGPSCQRSCQPGRYGKR------CVPCKCANHS 628
G C C GP C C+ G + R C PC C+ S
Sbjct: 1116 GACPCKENVFGPQC-NECREGTFALRADNPLGCSPCFCSGLS 1156
Score = 146 bits (369), Expect = 9e-35
Identities = 128/462 (27%), Positives = 172/462 (37%), Gaps = 97/462 (20%)
Query: 334 CLCEHGFTGDRCTDRLCPDGFY-------GLSCQAPCTCDREHSLSCHPMNGEC-SCLPG 385
C C G+TG C C G+Y G CQ PC C H+ C+ ++G C +C
Sbjct: 709 CECPQGYTGTSCES--CLSGYYRVDGILFGGICQ-PCEC-HGHAAECN-VHGVCIACAHN 763
Query: 386 WAGLHCNESCP----QDTHG-PGCQEHCLCL-------HGGVCQATSG---LCQ-CAPGY 429
G+HC + P + + G PG + C C C G +C CAPGY
Sbjct: 764 TTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGY 823
Query: 430 TGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFS 489
+G C C YG SC VPC
Sbjct: 824 SGAWCER-CADGYYGNPTVPGESC-------------------------VPC-------D 850
Query: 490 CNASCQCAHEAVCSPQTGACT-CTPGWHGAHCQLPCPKGQFGEGCASR----CDC----D 540
C+ + + C TG C C GAHC+ C G +G+ ++ C+C
Sbjct: 851 CSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER-CADGFYGDAVTAKNCRACECHVKGS 909
Query: 541 HSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSN---TCTCKNGGTC---LPENGN 594
HS C G C C+ G +C C G +G++ + C C G+ + G
Sbjct: 910 HSAVCHLETGLCDCKPNVTGQQCD-QCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQ 968
Query: 595 CVCAPGFRGPSCQRSCQPGRYGKR---CVPCKCAN-HSFCHPSNGTCYCLAGWTGPDCSQ 650
C C PG G C R C G Y + C PC C + + C P G C C G C +
Sbjct: 969 CHCVPGVAGKRCDR-CAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEE 1027
Query: 651 PCPPGHWGENC---AQTCQCHHGGTCHPQ----DGSCICPLGWTGHHCLEGCPLGTFGAN 703
C GHWG + Q C C G+ H + G C C + G C + C LG
Sbjct: 1028 -CEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRAC-DQCSLGYRDFP 1085
Query: 704 CSQPCQCG----PGEKCHPETGACVCPPGHSGAPCRIGIQEP 741
PC C G+ C+ E G C C PC+ + P
Sbjct: 1086 DCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGP 1127
Score = 132 bits (332), Expect = 2e-30
Identities = 140/493 (28%), Positives = 182/493 (36%), Gaps = 117/493 (23%)
Query: 120 CQCVPGWRGDDCSSECAPG-------MWGPQCDKPCSC-GNNSSCDPKSGVCSCPSGLQP 171
C+C G+ G C S C G ++G C +PC C G+ + C+ +C
Sbjct: 709 CECPQGYTGTSCES-CLSGYYRVDGILFGGIC-QPCECHGHAAECNVHGVCIACAHNTTG 766
Query: 172 PNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPS 231
+C Q C PG+YG + G P D Q C CP S F P+
Sbjct: 767 VHCEQ-CLPGFYGEPSR------GTPGDCQ--PCACPLTI------------ASNNFSPT 805
Query: 232 THSCQNGGVFQTPQGSCS-CPPGWMGTICSLPCPEGFHGP-----------NCSQECRCH 279
H V C C PG+ G C C +G++G +CS
Sbjct: 806 CHLNDGDEVV------CDWCAPGYSGAWCE-RCADGYYGNPTVPGESCVPCDCSGNVDPS 858
Query: 280 NGGLCDRFTGQC-RCAPGYTGDRCREECPVGRFG-----QDCAETCDC----APDARCFP 329
G CD TG+C +C G C E C G +G ++C C+C + A C
Sbjct: 859 EAGHCDSVTGECLKCLGNTDGAHC-ERCADGFYGDAVTAKNC-RACECHVKGSHSAVCHL 916
Query: 330 ANGACLCEHGFTGDRCTDRLCPDGFYGL----SCQAPCTCDREHSLS--CHPMNGECSCL 383
G C C+ TG +C C G+YGL C+ PC C S+S C G+C C+
Sbjct: 917 ETGLCDCKPNVTGQQCDQ--CLHGYYGLDSGHGCR-PCNCSVAGSVSDGCTD-EGQCHCV 972
Query: 384 PGWAGLHCNESCPQD--THGPGCQEHCLCLH-GGVCQATSGLCQCAPGYTGPHCASLCPP 440
PG AG C + C + G C C H C +G C C P G C C
Sbjct: 973 PGVAGKRC-DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEE-CED 1030
Query: 441 DTYG----VNCSARCSC----ENAIACSPIDGECVCKEGWQRGNCS------------VP 480
+G V C A C+C C + G C CK + C VP
Sbjct: 1031 GHWGYDAEVGCQA-CNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVP 1089
Query: 481 CP---PGTWGFSCNAS---CQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCA 534
C GT G +CN C C E TGAC C G C C +G F
Sbjct: 1090 CDCDLRGTSGDACNLEQGLCGCVEE------TGACPCKENVFGPQCN-ECREGTFA---- 1138
Query: 535 SRCDCDHSDGCDP 547
D+ GC P
Sbjct: 1139 --LRADNPLGCSP 1149
Score = 82.4 bits (202), Expect = 2e-15
Identities = 85/314 (27%), Positives = 110/314 (35%), Gaps = 73/314 (23%)
Query: 82 TDHRQRLQCCHGFYESRGFCVPLCAQEC-VHGRCVA-----PNQCQCVPGWRGDDCSSEC 135
TD +C GFY A EC V G A C C P G C +C
Sbjct: 877 TDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCD-QC 935
Query: 136 APGMWGPQCD---KPCSC---GNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYY----GP 185
G +G +PC+C G+ S G C C G+ C C G+Y G
Sbjct: 936 LHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRC-DRCAHGFYAYQDGS 994
Query: 186 ACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ 245
C CDP+TG C CP G C+ C G G+ + CQ
Sbjct: 995 CTPCDCPHTQNTCDPETGECVCPPHTQGVKCE-ECEDGHWGY--DAEVGCQ--------- 1042
Query: 246 GSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREE 305
+C NCS H+ CD TG C+C + G C ++
Sbjct: 1043 -AC----------------------NCSLVGSTHH--RCDVVTGHCQCKSKFGGRAC-DQ 1076
Query: 306 CPVG-RFGQDCAETCDC-----APDA--------RCFPANGACLCEHGFTGDRCTDRLCP 351
C +G R DC CDC + DA C GAC C+ G +C + C
Sbjct: 1077 CSLGYRDFPDCV-PCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNE--CR 1133
Query: 352 DGFYGLSCQAPCTC 365
+G + L P C
Sbjct: 1134 EGTFALRADNPLGC 1147
Score = 78.6 bits (192), Expect = 3e-14
Identities = 63/182 (34%), Positives = 73/182 (40%), Gaps = 44/182 (24%)
Query: 594 NCVCAPGFRGPSCQRSCQPGRY----------GKR-----CVPCKCANHS-FCHPSNGTC 637
NCVC PG G SCQ C PG + G R CVPC C NHS C P+ G C
Sbjct: 1361 NCVCPPGTVGFSCQ-DCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKC 1419
Query: 638 YCLAGWTGPDCSQPCPPGHWGE------NCAQTCQCHH------GGTC---HPQDGSC-I 681
T D C G++G+ +CA C C H TC D C
Sbjct: 1420 LNCGDNTAGDHCDVCTSGYYGKVTGSASDCA-LCACPHSPPASFSPTCVLEGDHDFRCDA 1478
Query: 682 CPLGWTGHHCLEGCPLGTFG-----ANCSQPCQCGPGEKCHPE----TGACVCPPGHSGA 732
C LG+ G HC E C +G Q C C P H + +G CVC G SG
Sbjct: 1479 CLLGYEGKHC-ERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGL 1537
Query: 733 PC 734
C
Sbjct: 1538 RC 1539
Score = 73.9 bits (180), Expect = 7e-13
Identities = 65/210 (30%), Positives = 79/210 (37%), Gaps = 52/210 (24%)
Query: 120 CQCVPGWRGDDCSSECAPGMW----------GPQ-----CDKPCSCGNNS-SCDPKSGVC 163
C C PG G C +CAPG GP+ C PCSC N+S +CDP +G C
Sbjct: 1362 CVCPPGTVGFSCQ-DCAPGYHRGKLPAGSDRGPRPLVAPC-VPCSCNNHSDTCDPNTGKC 1419
Query: 164 -SCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQ 222
+C +C CT GYYG C C A F P D C
Sbjct: 1420 LNCGDNTAGDHC-DVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
Query: 223 GTSGFFCPSTHSCQNG--GVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHN 280
G+ C + G QTP GSC Q+C C+
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSC-------------------------QKCDCNP 1513
Query: 281 GGL----CDRFTGQCRCAPGYTGDRCREEC 306
G CDR +GQC C G +G RC +EC
Sbjct: 1514 HGSVHGDCDRTSGQCVCRLGASGLRC-DEC 1542
Score = 73.2 bits (178), Expect = 1e-12
Identities = 73/270 (27%), Positives = 101/270 (37%), Gaps = 58/270 (21%)
Query: 148 CSC-GNNSSCD----PKSGVCSCPSGLQPPNCLQPCTPGYY-----------GPACQFRC 191
C C G+ SSC K C C +C + C PGY+ G C+ C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNR-CCPGYHQQPWRPGTVSSGNTCE-AC 327
Query: 192 QCHGAPCD--------PQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNG----- 238
CH D Q + + G ++C Q T G C +C +G
Sbjct: 328 NCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINC---ETCIDGYYRPH 384
Query: 239 ---GVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAP 295
P C+C P +G++ S+ + H HNG + GQC C
Sbjct: 385 KVSPYEDEPCRPCNCDP--VGSLSSVCIKDDLHSD-------LHNG----KQPGQCPCKE 431
Query: 296 GYTGDRCREECPVGRFGQDCAETCDCAP--DARCFPANGACLCEHGFTGDRCTDRLCPDG 353
GYTG++C + C +G +C C P A P G C+C+ G C DR C G
Sbjct: 432 GYTGEKC-DRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKAC-DR-CKPG 488
Query: 354 FYGLSCQAPCTCDREHSLSCHPMNGECSCL 383
FY L + P C C ++ CS L
Sbjct: 489 FYNLKEKNPRGCS---ECFCFGVSDVCSSL 515
Score = 73.2 bits (178), Expect = 1e-12
Identities = 68/235 (28%), Positives = 85/235 (36%), Gaps = 65/235 (27%)
Query: 247 SCSCPPGWMGTICSLPCPEGFH----------GPNC----SQECRCHN-GGLCDRFTGQC 291
+C CPPG +G C C G+H GP C C+N CD TG+C
Sbjct: 1361 NCVCPPGTVGFSCQ-DCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKC 1419
Query: 292 -RCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLC 350
C GD C + C G +G+ DCA C C H
Sbjct: 1420 LNCGDNTAGDHC-DVCTSGYYGKVTGSASDCA----------LCACPHSPPA-------- 1460
Query: 351 PDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHG----PG--C 404
S C + +H C +CL G+ G HC E C +G PG C
Sbjct: 1461 -------SFSPTCVLEGDHDFRCD------ACLLGYEGKHC-ERCSSSYYGNPQTPGGSC 1506
Query: 405 QEHCLCLHGGV---CQATSGLCQCAPGYTGPHCASLCPP-----DTYGVNCSARC 451
Q+ HG V C TSG C C G +G C C P +T V+C C
Sbjct: 1507 QKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE-CEPRHILMETDCVSCDDEC 1560
Score = 68.2 bits (165), Expect = 4e-11
Identities = 60/206 (29%), Positives = 78/206 (37%), Gaps = 53/206 (25%)
Query: 481 CPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKG--QFGEGCASRCD 538
CPPGT GFSC C PG+H +G C C
Sbjct: 1364 CPPGTVGFSCQ------------------DCAPGYHRGKLPAGSDRGPRPLVAPCVP-CS 1404
Query: 539 C-DHSDGCDPVHGRC-QCQAGWMGARCHLSCPEGLWG------VNCSNTCTCKN------ 584
C +HSD CDP G+C C G C + C G +G +C+ C C +
Sbjct: 1405 CNNHSDTCDPNTGKCLNCGDNTAGDHCDV-CTSGYYGKVTGSASDCA-LCACPHSPPASF 1462
Query: 585 GGTCLPENGN---C-VCAPGFRGPSCQRSCQPGRYGK------RCVPCKC----ANHSFC 630
TC+ E + C C G+ G C+R C YG C C C + H C
Sbjct: 1463 SPTCVLEGDHDFRCDACLLGYEGKHCER-CSSSYYGNPQTPGGSCQKCDCNPHGSVHGDC 1521
Query: 631 HPSNGTCYCLAGWTGPDCSQPCPPGH 656
++G C C G +G C + C P H
Sbjct: 1522 DRTSGQCVCRLGASGLRCDE-CEPRH 1546
Score = 62.0 bits (149), Expect = 3e-09
Identities = 77/294 (26%), Positives = 101/294 (34%), Gaps = 77/294 (26%)
Query: 408 CLCL-HGGVC---QATSGL-CQCAPGYTGPHCASLCP--------PDTY--GVNCSARCS 452
C+C H C + T L CQC G C CP P T G C A C+
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEA-CN 328
Query: 453 CENAIACSPIDGECVCKEG--------WQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSP 504
C N D E V K+ ++ G + C T G +C
Sbjct: 329 CHNKAKDCYYD-ESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE------------- 374
Query: 505 QTGACTCTPGWHGAH---------CQLPC---PKGQFGEGCASRCDCDHSD---GCDPVH 549
TC G++ H C+ PC P G C D HSD G P
Sbjct: 375 -----TCIDGYYRPHKVSPYEDEPCR-PCNCDPVGSLSSVCIK--DDLHSDLHNGKQP-- 424
Query: 550 GRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPE--NGNCVCAPGFRGPSCQ 607
G+C C+ G+ G +C C G +C C G+ E G CVC G +C
Sbjct: 425 GQCPCKEGYTGEKCD-RCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACD 483
Query: 608 RSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCL----------AGWTGPDCSQP 651
R C+PG Y + + + FC + C L +GW D P
Sbjct: 484 R-CKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISP 536
Score = 58.2 bits (139), Expect = 4e-08
Identities = 61/217 (28%), Positives = 75/217 (34%), Gaps = 52/217 (23%)
Query: 524 CPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCK 583
CP G G C C P + R + AG L P C+C
Sbjct: 1364 CPPGTVGFSCQD---------CAPGYHRGKLPAGSDRGPRPLVAP--------CVPCSCN 1406
Query: 584 N-GGTCLPENGNCV-CAPGFRGPSCQRSCQPGRYGK------RCVPCKCANHSFCHPSNG 635
N TC P G C+ C G C C G YGK C C C HS +
Sbjct: 1407 NHSDTCDPNTGKCLNCGDNTAGDHCD-VCTSGYYGKVTGSASDCALCACP-HSPPASFSP 1464
Query: 636 TCY-----------CLAGWTGPDCSQPCPPGHWGE-----NCAQTCQCH-HG---GTCHP 675
TC CL G+ G C + C ++G Q C C+ HG G C
Sbjct: 1465 TCVLEGDHDFRCDACLLGYEGKHCER-CSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDR 1523
Query: 676 QDGSCICPLGWTGHHCLEGCP----LGTFGANCSQPC 708
G C+C LG +G C E P + T +C C
Sbjct: 1524 TSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDEC 1560
Score = 52.0 bits (123), Expect = 3e-06
Identities = 71/265 (26%), Positives = 91/265 (34%), Gaps = 69/265 (26%)
Query: 275 ECRC-HN--GGLCDRFTGQCRCAPGY-----------TGDRCREECPVGRFGQDC----- 315
+C+C HN G C+R C PGY +G+ C E C +DC
Sbjct: 289 QCQCEHNTCGESCNR------CCPGYHQQPWRPGTVSSGNTC-EACNCHNKAKDCYYDES 341
Query: 316 -AETCDCAPDARCFPANGACL-CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS- 372
A+ A F G C+ C G C C DG+Y R H +S
Sbjct: 342 VAKQKKSLNTAGQFRGGGVCINCLQNTMGINC--ETCIDGYY-----------RPHKVSP 388
Query: 373 -----CHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAP 427
C P C+C P G + D H LH G G C C
Sbjct: 389 YEDEPCRP----CNCDP--VGSLSSVCIKDDLHSD--------LHNG---KQPGQCPCKE 431
Query: 428 GYTGPHC--ASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGT 485
GYTG C L D Y S C+ + + P G CVCKE + C C PG
Sbjct: 432 GYTGEKCDRCQLGYKD-YPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACD-RCKPGF 489
Query: 486 WGFSCNASCQCAHEAVCSPQTGACT 510
+ C+ E C + C+
Sbjct: 490 YNLKEKNPRGCS-ECFCFGVSDVCS 513
Score = 47.4 bits (111), Expect = 7e-05
Identities = 52/208 (25%), Positives = 69/208 (33%), Gaps = 38/208 (18%)
Query: 551 RCQCQAGWMGARCHLSCP---EGLW---GVNCSNTC----------TCKNGGTCLPENGN 594
+CQC+ G C+ CP + W V+ NTC C + + +
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 595 CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPC-- 652
A FRG +C G C C + P + Y + +PC
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETC---IDGYYRPHKVSPY------EDEPCRPCNC 399
Query: 653 -PPGHWGENCAQT---CQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPC 708
P G C + H+G Q G C C G+TG C + C LG C
Sbjct: 400 DPVGSLSSVCIKDDLHSDLHNG----KQPGQCPCKEGYTGEKC-DRCQLGYKDYPTCVSC 454
Query: 709 QCGP--GEKCHPETGACVCPPGHSGAPC 734
C P P TG CVC G C
Sbjct: 455 GCNPVGSASDEPCTGPCVCKENVEGKAC 482
Score = 47.4 bits (111), Expect = 7e-05
Identities = 61/232 (26%), Positives = 80/232 (34%), Gaps = 63/232 (27%)
Query: 334 CLCEHGFTGDRCTDRLCPDGFYGLSCQA--------------PCTCDREHSLSCHPMNGE 379
C+C G G C D C G++ A PC+C+ HS +C P G+
Sbjct: 1362 CVCPPGTVGFSCQD--CAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNN-HSDTCDPNTGK 1418
Query: 380 C-SCLPGWAGLHCNESCPQDTHGP--GCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCAS 436
C +C AG HC + C +G G C LC C PH
Sbjct: 1419 CLNCGDNTAGDHC-DVCTSGYYGKVTGSASDC------------ALCAC------PHS-- 1457
Query: 437 LCPPDTYGVNCSARCSCENAIACSPIDGEC-VCKEGWQRGNC-----SVPCPPGTWGFSC 490
PP ++ C + D C C G++ +C S P T G SC
Sbjct: 1458 --PPASFSPTC---------VLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSC 1506
Query: 491 NASCQC-AHEAV---CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCD 538
C C H +V C +G C C G G C P+ E CD
Sbjct: 1507 Q-KCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCD 1557
Score = 40.0 bits (92), Expect = 0.011
Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 9/86 (10%)
Query: 117 PNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCG--NNSSCDPKSGVCSCPSGLQPPNC 174
P QC C G+ G+ C C G C C ++S +P +G C C ++ C
Sbjct: 424 PGQCPCKEGYTGEKC-DRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKAC 482
Query: 175 LQPCTPGYY-----GPACQFRCQCHG 195
C PG+Y P C C G
Sbjct: 483 -DRCKPGFYNLKEKNPRGCSECFCFG 507
Score = 32.7 bits (73), Expect = 1.8
Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 19/89 (21%)
Query: 103 PLCAQECVHG-RCVAPNQCQCVPGWRGDDCSSECAPGMWG-PQ-----CDKPCSCGNNSS 155
P C E H RC A C+ G+ G C C+ +G PQ C K C C + S
Sbjct: 1464 PTCVLEGDHDFRCDA-----CLLGYEGKHCE-RCSSSYYGNPQTPGGSCQK-CDCNPHGS 1516
Query: 156 ----CDPKSGVCSCPSGLQPPNCLQPCTP 180
CD SG C C G C C P
Sbjct: 1517 VHGDCDRTSGQCVCRLGASGLRC-DECEP 1544
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 149 bits (375), Expect = 2e-35
Identities = 127/442 (28%), Positives = 176/442 (39%), Gaps = 77/442 (17%)
Query: 349 LCPDGFYGLSCQAPCTCDREH--SLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQE 406
+C D +YG +C C +H C P +G SCLPGW G E C Q GC E
Sbjct: 174 ICSDNYYGDNCSRLCKKRNDHFGHYVCQP-DGNLSCLPGWTG----EYCQQPICLSGCHE 228
Query: 407 HCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGEC 466
G C + C C PG+ G C P + C + +P +C
Sbjct: 229 Q-----NGYCSKPAE-CLCRPGWQGRLCNECIPHN----------GCRHGTCSTP--WQC 270
Query: 467 VCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPK 526
C EGW C T C C++ ++ CTC PG+ G C+L +
Sbjct: 271 TCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSG---QRSYTCTCRPGYTGVDCELELSE 327
Query: 527 GQFGEGCASRCDC-DHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNG 585
C + C D DG C C G+ G C S ++C+++ C NG
Sbjct: 328 CD-SNPCRNGGSCKDQEDGY-----HCLCPPGYYGLHCEHST------LSCADS-PCFNG 374
Query: 586 GTCLPENGN----CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC---HPSNGTCY 638
G+C N C C P F G +C++ RC CAN C PS C
Sbjct: 375 GSCRERNQGANYACECPPNFTGSNCEKKVD------RCTSNPCANGGQCLNRGPSR-MCR 427
Query: 639 CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS--CICPLGWTGHHCLEGCP 696
C G+TG C +CA+ C HGGTCH + C CP G++G C
Sbjct: 428 CRPGFTGTYCELHV------SDCARN-PCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT- 479
Query: 697 LGTFGANCSQPC--QCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTTPVAYNS 754
+ A S PC + +T C CP G G+ C P + P+ P S
Sbjct: 480 --SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEF----PVGLPPSFPWVAVS 533
Query: 755 LGAVIGIAVLGSLVVALVALFI 776
LG +G+AVL +++ +VA+ +
Sbjct: 534 LG--VGLAVL-LVLLGMVAVAV 552
Score = 129 bits (325), Expect = 1e-29
Identities = 105/388 (27%), Positives = 147/388 (37%), Gaps = 87/388 (22%)
Query: 263 CPEGFHGPNCSQECRCHN---GGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETC 319
C + ++G NCS+ C+ N G + G C PG+TG+ C++ P+ C C
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQ--PI------CLSGC 226
Query: 320 DCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGE 379
PA CLC G+ G C + + +G +C P +
Sbjct: 227 HEQNGYCSKPAE--CLCRPGWQGRLCNECIPHNGCRHGTCSTPW---------------Q 269
Query: 380 CSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCA---- 435
C+C GW GL C++ TH C+ C + G S C C PGYTG C
Sbjct: 270 CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSG---QRSYTCTCRPGYTGVDCELELS 326
Query: 436 ---------------------SLCPPDTYGVNCS-ARCSCENAIACSPIDGECVCKEGWQ 473
LCPP YG++C + SC A SP C+E Q
Sbjct: 327 ECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSC----ADSPCFNGGSCRERNQ 382
Query: 474 RGNCSVPCPPGTWGFSCN------ASCQCAHEAVCSPQ--TGACTCTPGWHGAHCQLPCP 525
N + CPP G +C S CA+ C + + C C PG+ G +C+L
Sbjct: 383 GANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHV- 441
Query: 526 KGQFGEGCASRCDCDHSDGCDPVHG--RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCK 583
CA R C H C + C C AG+ G RC + ++ + C
Sbjct: 442 -----SDCA-RNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT-----SIDACASSPCF 490
Query: 584 NGGTCLPENGN----CVCAPGFRGPSCQ 607
N TC + C C GF G C+
Sbjct: 491 NRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 115 bits (288), Expect = 2e-25
Identities = 118/429 (27%), Positives = 152/429 (35%), Gaps = 115/429 (26%)
Query: 87 RLQCCHGFYESRGFCVPLCAQECVHGR---CVAPNQCQCVPGWRGDDCSSECAPGMWGPQ 143
R+ C +Y C LC + H C C+PGW G+ C P
Sbjct: 172 RVICSDNYYGDN--CSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQ--------PI 221
Query: 144 CDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTG 203
C S C ++G CS +P CL C PG+ G C C H C + G
Sbjct: 222 C--------LSGCHEQNGYCS-----KPAECL--CRPGWQGRLCN-ECIPHNG-C--RHG 262
Query: 204 ACFCPAERTGPSCDVSCSQGTSGFFCPS-----TH--SCQNGGVFQTP---QGSCSCPPG 253
C P + T C +G G FC TH C+NG +C+C PG
Sbjct: 263 TCSTPWQCT-------CDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPG 315
Query: 254 WMGTICSLPCPEGFHGPNCSQECRCHNGGLC-DRFTG-QCRCAPGYTGDRCREECPVGRF 311
+ G C L E P C NGG C D+ G C C PGY G C
Sbjct: 316 YTGVDCELELSECDSNP-------CRNGGSCKDQEDGYHCLCPPGYYGLHCEH------- 361
Query: 312 GQDCAETCDCAPDARCF----------PANGACLCEHGFTG-------DRCTDRLCPDGF 354
T CA D+ CF AN AC C FTG DRCT C +G
Sbjct: 362 -----STLSCA-DSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGG 415
Query: 355 YGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGG 414
L+ + P + C C PG+ G +C + H C + C HGG
Sbjct: 416 QCLN-RGP--------------SRMCRCRPGFTGTYC------ELHVSDCARN-PCAHGG 453
Query: 415 VCQATSG--LCQCAPGYTGPHCASLCPPDTYGVN-CSARCSCENAIACSPIDGECVCKEG 471
C +C C G++G C D + C R +C ++ C C G
Sbjct: 454 TCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTF--VCNCPYG 511
Query: 472 WQRGNCSVP 480
+ C P
Sbjct: 512 FVGSRCEFP 520
Score = 103 bits (257), Expect = 8e-22
Identities = 97/343 (28%), Positives = 125/343 (36%), Gaps = 74/343 (21%)
Query: 83 DHRQRLQCCHGFYESRGFCVP----LC--------AQECV------HGRCVAPNQCQCVP 124
++ Q+ C G +E G+C LC EC+ HG C P QC C
Sbjct: 215 EYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDE 274
Query: 125 GWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYG 184
GW G C + C ++S C K+G SG + C C PGY G
Sbjct: 275 GWGGLFCDQDLN------------YCTHHSPC--KNGATCSNSGQRSYTC--TCRPGYTG 318
Query: 185 PACQFR-CQCHGAPC-------DPQTG-ACFCPAERTGPSCD---VSCSQGTSGFFCPST 232
C+ +C PC D + G C CP G C+ +SC+ C +
Sbjct: 319 VDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSP----CFNG 374
Query: 233 HSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRF--TGQ 290
SC+ Q +C CPP + G+ C P C NGG C +
Sbjct: 375 GSCRERN--QGANYACECPPNFTGSNCEKKVDRCTSNP-------CANGGQCLNRGPSRM 425
Query: 291 CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFP-ANG-ACLCEHGFTGDRCTDR 348
CRC PG+TG C DCA CA C NG C C GF+G RC R
Sbjct: 426 CRCRPGFTGTYCELHV------SDCARN-PCAHGGTCHDLENGLMCTCPAGFSGRRCEVR 478
Query: 349 LCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHC 391
D C TC + S C+C G+ G C
Sbjct: 479 TSIDACASSPCFNRATCYTDLSTDTF----VCNCPYGFVGSRC 517
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 146 bits (369), Expect = 9e-35
Identities = 122/418 (29%), Positives = 157/418 (37%), Gaps = 95/418 (22%)
Query: 120 CQCVPGWRGDDCSSECAPG------MWGPQCD-KPCSCGNNSSCDPKSGVCSCPSGLQPP 172
C C G+ G C S CAPG GP PC+C + +CDP +G+C C + P
Sbjct: 673 CSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
Query: 173 NCLQPCTPGYYG-PACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPS 231
+C + C PG+YG P C PC Q+ P R +V C
Sbjct: 732 SC-ERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESR-----EVVC----------- 774
Query: 232 THSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG--------PNCSQECRCHNG-- 281
TH CPPG G C + C +GF G P +C+C
Sbjct: 775 TH----------------CPPGQRGRRCEV-CDDGFFGDPLGLFGHPQPCHQCQCSGNVD 817
Query: 282 ----GLCDRFTGQC-RCAPGYTGDRCREECPVGRFGQ-------DCAETCDCAPDAR--- 326
G CD +G C RC TGD C E C G +G D C C P
Sbjct: 818 PNAVGNCDPLSGHCLRCLHNTTGDHC-EHCQEGFYGSALAPRPADKCMPCSCHPQGSVSE 876
Query: 327 ---CFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSL-----SCHPMNG 378
C P G C C T C+ C GF+ L C + H L CHP G
Sbjct: 877 QMPCDPVTGQCSCLPHVTARDCS--RCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTG 934
Query: 379 ECSCLPGWAGLHCNESCPQDTHG---PGCQEHCLCLHGGVCQA---TSGLCQCAPGYTGP 432
+C+C PG G C + C G GC+ C C G A +G C C PG+ G
Sbjct: 935 QCTCRPGVTGQAC-DRCQLGFFGFSIKGCRA-CRCSPLGAASAQCHENGTCVCRPGFEGY 992
Query: 433 HCASLCPPDTY----GVNCSARCSCENAI--ACSPIDGECVCKEGWQRG-NCSVPCPP 483
C C + + G +C SC + + + EGW +G +C P P
Sbjct: 993 KC-DRCHDNFFLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGP 1049
Score = 136 bits (343), Expect = 9e-32
Identities = 107/367 (29%), Positives = 138/367 (37%), Gaps = 98/367 (26%)
Query: 422 LCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPC 481
+C C GYTG C S C G++R
Sbjct: 672 ICSCPTGYTGQFCES-------------------------------CAPGYKR-----EM 695
Query: 482 PPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASR----- 536
P G SC C C C P TG C C+ G C+ C G +G A +
Sbjct: 696 PQGGPYASC-VPCTCNQHGTCDPNTGICVCSHHTEGPSCER-CLPGFYGNPFAGQADDCQ 753
Query: 537 -CDCDHSDGCDPVHGRCQ-----CQAGWMGARCHLSCPEGLWG--------------VNC 576
C C C + + C G G RC + C +G +G C
Sbjct: 754 PCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV-CDDGFFGDPLGLFGHPQPCHQCQC 812
Query: 577 SNTCTCKNGGTCLPENGNCV-CAPGFRGPSCQRSCQPGRYGK--------RCVPCKC--- 624
S G C P +G+C+ C G C+ CQ G YG +C+PC C
Sbjct: 813 SGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH-CQEGFYGSALAPRPADKCMPCSCHPQ 871
Query: 625 ---ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHW----GENCAQTCQCHHGGT----C 673
+ C P G C CL T DCS+ C PG + G C ++C+CH G+ C
Sbjct: 872 GSVSEQMPCDPVTGQCSCLPHVTARDCSR-CYPGFFDLQPGRGC-RSCKCHPLGSQEDQC 929
Query: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCS--QPCQCGP----GEKCHPETGACVCPP 727
HP+ G C C G TG C + C LG FG + + C+C P +CH E G CVC P
Sbjct: 930 HPKTGQCTCRPGVTGQAC-DRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRP 987
Query: 728 GHSGAPC 734
G G C
Sbjct: 988 GFEGYKC 994
Score = 131 bits (330), Expect = 3e-30
Identities = 125/457 (27%), Positives = 158/457 (34%), Gaps = 130/457 (28%)
Query: 248 CSCPPGWMGTICSLPCPEGFH------GPNCS-QECRCHNGGLCDRFTGQCRCAPGYTGD 300
CSCP G+ G C C G+ GP S C C+ G CD TG C C+ G
Sbjct: 673 CSCPTGYTGQFCE-SCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
Query: 301 RCREECPVGRFGQ------DCAETCDCAPDARC--FPANGACLCEH---GFTGDRCTDRL 349
C E C G +G D + C C + C P + +C H G G RC +
Sbjct: 732 SC-ERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRC--EV 788
Query: 350 CPDGFYG------------LSCQAPCTCDREHSLSCHPMNGEC-SCLPGWAGLHCNESCP 396
C DGF+G CQ D +C P++G C CL G HC E C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC-EHCQ 847
Query: 397 QDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENA 456
+ +G P A C P +C + S
Sbjct: 848 EGFYGSAL--------------------------APRPADKCMP----CSCHPQGSVSEQ 877
Query: 457 IACSPIDGECVCKEGWQRGNCSVPCPPGTW----GFSCNASCQC----AHEAVCSPQTGA 508
+ C P+ G+C C +CS C PG + G C SC+C + E C P+TG
Sbjct: 878 MPCDPVTGQCSCLPHVTARDCS-RCYPGFFDLQPGRGCR-SCKCHPLGSQEDQCHPKTGQ 935
Query: 509 CTCTPGWHGAHCQLPCPKGQFG---EGCASRCDCDHSDGCDPVHGRCQCQ-AGWMGARCH 564
CTC PG G C C G FG +GC + C+C G A+CH
Sbjct: 936 CTCRPGVTGQACD-RCQLGFFGFSIKGCRA----------------CRCSPLGAASAQCH 978
Query: 565 LSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS------CQPGRYGKR 618
ENG CVC PGF G C R G + ++
Sbjct: 979 --------------------------ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQ 1012
Query: 619 CVPCKCANHSFCHPSNGTCYCLAGW-TGPDCSQPCPP 654
C C GW G DC P P
Sbjct: 1013 CPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGP 1049
Score = 117 bits (294), Expect = 4e-26
Identities = 178/712 (25%), Positives = 234/712 (32%), Gaps = 192/712 (26%)
Query: 89 QCCHGFY--ESRGFCVPLCAQEC--VHGRCVAPNQCQCVP---GWRGDDCSSECAPGMWG 141
+C FY + R C P Q +H +C C C P GW+ D C PG
Sbjct: 366 RCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCD----RCLPGFHS 421
Query: 142 PQ---CDKPCSC---GNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHG 195
C +PC+C G+ +CDP+SG C C ++ N C PG + C
Sbjct: 422 LSEGGC-RPCTCNPAGSLDTCDPRSGRCPCKENVE-GNLCDRCRPGTFNLQPHNPAGCSS 479
Query: 196 APCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQN------GGVFQTPQG--S 247
C + C A+ QG G++ S ++ GV +P+
Sbjct: 480 CFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEE 539
Query: 248 CSCPPGWMG---------TICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYT 298
+ P ++G I + P G + R GL P
Sbjct: 540 LTAPEKFLGDQRFSYGQPLILTFRVPPG--DSPLPVQLRLEGTGLALSLRHSSLSGPQDA 597
Query: 299 GDRCREECPVGRFG-QDCAETCDCAPDARCF---------------------PANGACLC 336
G E RF Q+ +E D AP F PA L
Sbjct: 598 GHPREVEL---RFHLQETSE--DVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLT 652
Query: 337 EHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSC-------HPMNGE-CSCLPGWAG 388
E T R L P + C P + SC P G SC+P
Sbjct: 653 EVRLTSAR--PGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN 710
Query: 389 LH--CNES-----CPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL---C 438
H C+ + C T GP C+ +C PG+ G A C
Sbjct: 711 QHGTCDPNTGICVCSHHTEGPSCE------------------RCLPGFYGNPFAGQADDC 752
Query: 439 PPDTYGVNCSARCSCENAIACS--PIDGECVCKEGWQRGNCSVPCPPGTWGFSCNA---- 492
P C C AC+ P E VC CPPG G C
Sbjct: 753 QP----------CPCPGQSACTTIPESREVVCTH----------CPPGQRGRRCEVCDDG 792
Query: 493 ----------------SCQCAHE------AVCSPQTGAC-TCTPGWHGAHCQLPCPKGQF 529
CQC+ C P +G C C G HC+ C +G +
Sbjct: 793 FFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCE-HCQEGFY 851
Query: 530 GEGCASR-------CDCDHSDG-------CDPVHGRCQCQAGWMGARCHLSCPEGLW--- 572
G A R C C H G CDPV G+C C C C G +
Sbjct: 852 GSALAPRPADKCMPCSC-HPQGSVSEQMPCDPVTGQCSCLPHVTARDCS-RCYPGFFDLQ 909
Query: 573 -GVNCSNTCTCKNGGT----CLPENGNCVCAPGFRGPSCQRSCQPGRYG---KRCVPCKC 624
G C +C C G+ C P+ G C C PG G +C R CQ G +G K C C+C
Sbjct: 910 PGRGC-RSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR-CQLGFFGFSIKGCRACRC 967
Query: 625 ----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHW----GENCAQTCQCH 668
A + CH NGTC C G+ G C + C + G +C Q C+
Sbjct: 968 SPLGAASAQCH-ENGTCVCRPGFEGYKCDR-CHDNFFLTADGTHCQQCPSCY 1017
Score = 60.5 bits (145), Expect = 8e-09
Identities = 41/119 (34%), Positives = 51/119 (42%), Gaps = 22/119 (18%)
Query: 637 CYCLAGWTGPDCSQPCPPGHWGE--------NCAQTCQCHHGGTCHPQDGSCICPLGWTG 688
C C G+TG C + C PG+ E +C C C+ GTC P G C+C G
Sbjct: 673 CSCPTGYTGQFC-ESCAPGYKREMPQGGPYASCVP-CTCNQHGTCDPNTGICVCSHHTEG 730
Query: 689 HHCLEGCPLGTFG------ANCSQPCQCGPGEKCH--PETGACVC---PPGHSGAPCRI 736
C E C G +G A+ QPC C C PE+ VC PPG G C +
Sbjct: 731 PSC-ERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
Score = 59.3 bits (142), Expect = 2e-08
Identities = 59/244 (24%), Positives = 78/244 (31%), Gaps = 59/244 (24%)
Query: 536 RCDCD-HSDGCDP-VHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENG 593
RC C+ H+ C P V G+ C+ C G +C
Sbjct: 270 RCKCNGHASECGPDVAGQLACR-----------CQHNTTGTDCER--------------- 303
Query: 594 NCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSF----------CHPSNGTCY-CLAG 642
C P F+ R + C+PC C+ S G C+ C
Sbjct: 304 ---CLPFFQDRPWARGTAEAAH--ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDH 358
Query: 643 WTGPDCSQPCPPG--HWGENC-AQTCQCHHGGTCHPQ---DGSCICP---LGWTGHHCLE 693
GP C + C HW Q C C G+ H Q G+C C GW CL
Sbjct: 359 TAGPHCER-CQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLP 417
Query: 694 GCPLGTFGANCSQPCQCGPG---EKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTTPV 750
G + +PC C P + C P +G C C G C F + P P
Sbjct: 418 G--FHSLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475
Query: 751 AYNS 754
+S
Sbjct: 476 GCSS 479
Score = 56.2 bits (134), Expect = 2e-07
Identities = 64/252 (25%), Positives = 80/252 (31%), Gaps = 69/252 (27%)
Query: 413 GGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGW 472
GG C+ +C P G A C +T G +C C P + W
Sbjct: 268 GGRCKCNGHASECGPDVAG-QLACRCQHNTTGTDCER---------CLPFFQD----RPW 313
Query: 473 QRGNCSVP--CPPGTWGFSCNASC---QCAHEAVCSPQTG----ACTCTPGWHGAHCQ-- 521
RG C P CN S +C + TG C G HC+
Sbjct: 314 ARGTAEAAHECLP------CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERC 367
Query: 522 ----------LPCPKGQFGEGCASRCDCDHSDG----CDPVHGRCQCQAGWMGARCHLSC 567
+PC CDC + CD G C C+ G +C
Sbjct: 368 QENFYHWDPRMPCQP----------CDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCL 416
Query: 568 P--EGLWGVNCSNTCTCKNGG---TCLPENGNCVCAPGFRGPSCQRSCQPGRYGKR---- 618
P L C CTC G TC P +G C C G C R C+PG + +
Sbjct: 417 PGFHSLSEGGC-RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDR-CRPGTFNLQPHNP 474
Query: 619 --CVPCKCANHS 628
C C C HS
Sbjct: 475 AGCSSCFCYGHS 486
Score = 53.9 bits (128), Expect = 8e-07
Identities = 53/209 (25%), Positives = 74/209 (35%), Gaps = 44/209 (21%)
Query: 90 CCHGFYESRGFCVPLCAQECVHGRC-------------VAPNQCQCVPGWRGDDCSSECA 136
C GFY S P A +C+ C QC C+P DC S C
Sbjct: 846 CQEGFYGSA--LAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDC-SRCY 902
Query: 137 PGMWGPQCDKPC-SC------GNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQF 189
PG + Q + C SC C PK+G C+C G+ C C G++G + +
Sbjct: 903 PGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQAC-DRCQLGFFGFSIK- 960
Query: 190 RCQCHGAPCDP---------QTGACFCPAERTGPSCD------VSCSQGTSGFFCPSTHS 234
C C P + G C C G CD + GT CPS ++
Sbjct: 961 --GCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYA 1018
Query: 235 CQNGGVFQTPQGSCSCPPGWM-GTICSLP 262
+ + + GW+ G+ C P
Sbjct: 1019 LVKEEAAKL-KARLTLTEGWLQGSDCGSP 1046
Score = 53.1 bits (126), Expect = 1e-06
Identities = 71/291 (24%), Positives = 89/291 (30%), Gaps = 91/291 (31%)
Query: 320 DCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGE 379
+C PD AC C+H TG C +R P F+ A T + H
Sbjct: 279 ECGPDVA---GQLACRCQHNTTGTDC-ERCLP--FFQDRPWARGTAEAAHE--------- 323
Query: 380 CSCLPGWAGLHCNESCPQDTHGPGCQEHCL--------CLHGGVCQATSGLCQCAPGYTG 431
CLP CN S G E C HGG C C G
Sbjct: 324 --CLP------CNCS--------GRSEECTFDRELFRSTGHGGRCH------HCRDHTAG 361
Query: 432 PHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCN 491
PHC C+E + + +PC P + +
Sbjct: 362 PHCER-------------------------------CQENFYHWDPRMPCQPCDCQSAGS 390
Query: 492 ASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPK-GQFGEGCASRCDCDHS---DGCDP 547
QC TG C C P G C P EG C C+ + D CDP
Sbjct: 391 LHLQC-------DDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDP 443
Query: 548 VHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCA 598
GRC C+ G C C G + + N C +C + VCA
Sbjct: 444 RSGRCPCKENVEGNLCD-RCRPGTFNLQPHNPAGC---SSCFCYGHSKVCA 490
Score = 51.2 bits (121), Expect = 5e-06
Identities = 63/233 (27%), Positives = 85/233 (36%), Gaps = 53/233 (22%)
Query: 190 RCQC--HGAPCDPQTG---ACFCPAERTGPSC--------DVSCSQGTSGFFCPSTHSCQ 236
RC+C H + C P AC C TG C D ++GT+ + H C
Sbjct: 270 RCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTA----EAAHECL 325
Query: 237 -------------NGGVFQTPQ--GSCS-CPPGWMGTICSLPCPEGFH--GPNCS-QECR 277
+ +F++ G C C G C C E F+ P Q C
Sbjct: 326 PCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCER-CQENFYHWDPRMPCQPCD 384
Query: 278 CHNGGL----CDRFTGQCRCAPGYTGDRCREECPVG--RFGQDCAETCDCAPDA---RCF 328
C + G CD TG C C P TG +C + C G + C C P C
Sbjct: 385 CQSAGSLHLQCDD-TGTCACKPTVTGWKC-DRCLPGFHSLSEGGCRPCTCNPAGSLDTCD 442
Query: 329 PANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECS 381
P +G C C+ G+ C DR C G + L P C S C+ + C+
Sbjct: 443 PRSGRCPCKENVEGNLC-DR-CRPGTFNLQPHNPAGCS---SCFCYGHSKVCA 490
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 143 bits (361), Expect = 7e-34
Identities = 132/446 (29%), Positives = 166/446 (37%), Gaps = 90/446 (20%)
Query: 319 CDCAPDAR----CFPANGACLCEHGFTGDRCTDRLCPDGF-YGLSCQAPCTCDREHSLS- 372
C+C P C P G C C G C +R P F +G S PC C + S++
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTC-NRCAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 373 -CHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCL-HGGVCQATSGLCQCAPGYT 430
C+P+ G+C C G C+ P P CQ C C H C +G C YT
Sbjct: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQP-CQCNGHADDCDPVTGECLNCQDYT 890
Query: 431 GPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSC 490
H C YG PI G G C PCP G
Sbjct: 891 MGHNCERCLAGYYG---------------DPIIG-----SGDHCRPC--PCPDGP----- 923
Query: 491 NASCQCAHEAVCSPQT--GACTCTPGWHGAHCQLPCPKGQFGE-----GCASRCDCDHS- 542
++ Q A P T AC C PG+ G+ C C G FG G C C ++
Sbjct: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNI 982
Query: 543 -----DGCDPVHGRC-QCQAGWMGARCHLSCPEGLWG----VNCSNTCTCKNGGT----- 587
+ CD GRC +C G C C G +G +C C C GT
Sbjct: 983 DTTDPEACDKETGRCLKCLYHTEGEHCQF-CRFGYYGDALQQDC-RKCVCNYLGTVQEHC 1040
Query: 588 ------CLPENGNCVCAPGFRGPSCQRSCQPGRY----GKRCVPCKC-ANHSF---CHPS 633
C G C+C P G +C R C P + G C PC C A HSF C+
Sbjct: 1041 NGSDCQCDKATGQCLCLPNVIGQNCDR-CAPNTWQLASGTGCDPCNCNAAHSFGPSCNEF 1099
Query: 634 NGTCYCLAGWTGPDCSQPCPPGHWGE---NCAQTCQCHHGG----TCHPQDGSCICPLGW 686
G C C+ G+ G CS+ C WG+ C + C C G C G C+C G
Sbjct: 1100 TGQCQCMPGFGGRTCSE-CQELFWGDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGV 1157
Query: 687 TGHHCLEGCPLGTFGA--NCSQPCQC 710
G C + C G G +C+ QC
Sbjct: 1158 EGPRC-DKCTRGYSGVFPDCTPCHQC 1182
Score = 139 bits (350), Expect = 1e-32
Identities = 119/397 (29%), Positives = 147/397 (37%), Gaps = 95/397 (23%)
Query: 415 VCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCE-------NAIACSPIDGECV 467
VC G CQC P G C + C P T+G S CE NA C+P+ G+C
Sbjct: 784 VCDPNGGQCQCRPNVVGRTC-NRCAPGTFGFGPSGCKPCECHLQGSVNAF-CNPVTGQCH 841
Query: 468 CKEGWQRGNCSVPCPPGTWGFSCNASCQC-AHEAVCSPQTGACT-------------CTP 513
C +G C C PG WGF CQC H C P TG C C
Sbjct: 842 CFQGVYARQCD-RCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLA 900
Query: 514 GWHGA-------HCQ-LPCPKG-----QFGEGCASRCDCDHSDGCDPVHGR--CQCQAGW 558
G++G HC+ PCP G QF C DPV + C C G+
Sbjct: 901 GYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQ----------DPVTLQLACVCDPGY 950
Query: 559 MGARCHLSCPEGLWG-----------VNCSNTCTCKNGGTCLPENGNCV-CAPGFRGPSC 606
+G+RC C G +G C N + C E G C+ C G C
Sbjct: 951 IGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 607 QRSCQPGRYG----KRCVPCKC-----------ANHSFCHPSNGTCYCLAGWTGPDCSQP 651
Q C+ G YG + C C C + C + G C CL G +C +
Sbjct: 1010 Q-FCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDR- 1067
Query: 652 CPPGHW----GENCAQTCQCH----HGGTCHPQDGSCICPLGWTGHHCLEGCPL--GTFG 701
C P W G C C C+ G +C+ G C C G+ G C E L G
Sbjct: 1068 CAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPD 1126
Query: 702 ANCSQPCQCGPG----EKCHPETGACVCPPGHSGAPC 734
C + C C P +C TG CVC G G C
Sbjct: 1127 VEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRC 1162
Score = 137 bits (345), Expect = 5e-32
Identities = 123/417 (29%), Positives = 152/417 (36%), Gaps = 80/417 (19%)
Query: 276 CRCHNGG----LCDRFTGQCRCAPGYTGDRCREECP-VGRFGQDCAETCDC----APDAR 326
C C G +CD GQC+C P G C P FG + C+C + +A
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 327 CFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGEC------ 380
C P G C C G +C DR C G +G PC C+ H+ C P+ GEC
Sbjct: 833 CNPVTGQCHCFQGVYARQC-DR-CLPGHWGFPSCQPCQCN-GHADDCDPVTGECLNCQDY 889
Query: 381 -------SCLPGW-------AGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCA 426
CL G+ +G HC D G Q C V + C C
Sbjct: 890 TMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLA--CVCD 947
Query: 427 PGYTGPHCASLCP-----PDTYGVNCSARCSCENAI------ACSPIDGECV-CKEGWQR 474
PGY G C P G +C C C N I AC G C+ C +
Sbjct: 948 PGYIGSRCDDCASGYFGNPSEVGGSCQP-CQCHNNIDTTDPEACDKETGRCLKCLYHTEG 1006
Query: 475 GNCSVPCPPGTWGFSCNASCQ---CAH-----------EAVCSPQTGACTCTPGWHGAHC 520
+C C G +G + C+ C + + C TG C C P G +C
Sbjct: 1007 EHCQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNC 1065
Query: 521 QLPCPKG---QFGEGC-ASRCDCDHSDG--CDPVHGRCQCQAGWMGARCHLSCPEGLWG- 573
P G GC C+ HS G C+ G+CQC G+ G C C E WG
Sbjct: 1066 DRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-ECQELFWGD 1124
Query: 574 --VNCSNTCTCKNGG----TCLPENGNCVCAPGFRGPSCQRSCQPGRYG--KRCVPC 622
V C C C G C G CVC G GP C + C G G C PC
Sbjct: 1125 PDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK-CTRGYSGVFPDCTPC 1179
Score = 135 bits (339), Expect = 3e-31
Identities = 134/444 (30%), Positives = 170/444 (38%), Gaps = 106/444 (23%)
Query: 191 CQCH-----GAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQ---NGGV-- 240
C+C + CDP G C C G +C+ C+ GT GF C+ G V
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCN-RCAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 241 FQTP-QGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCH-NGGLCDRFTGQC------- 291
F P G C C G C P + P+C Q C+C+ + CD TG+C
Sbjct: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSC-QPCQCNGHADDCDPVTGECLNCQDYT 890
Query: 292 ------RCAPGY-------TGDRCRE-ECPVG-RFGQDCAETCDCAPDARCFPANGACLC 336
RC GY +GD CR CP G G+ A +C P AC+C
Sbjct: 891 MGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDP----VTLQLACVC 946
Query: 337 EHGFTGDRCTDRLCPDGFYGL------SCQAPCTC----DREHSLSCHPMNGEC-SCLPG 385
+ G+ G RC D C G++G SCQ PC C D +C G C CL
Sbjct: 947 DPGYIGSRCDD--CASGYFGNPSEVGGSCQ-PCQCHNNIDTTDPEACDKETGRCLKCLYH 1003
Query: 386 WAGLHC--------NESCPQDTHGPGC------QEHCLCLHGGVCQA--TSGLCQCAPGY 429
G HC ++ QD C QEHC +G CQ +G C C P
Sbjct: 1004 TEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHC---NGSDCQCDKATGQCLCLPNV 1060
Query: 430 TGPHCASLCPPDTY----GVNCSARCSCENA----IACSPIDGECVCKEGWQRGNCSVPC 481
G +C C P+T+ G C C+C A +C+ G+C C G+ CS C
Sbjct: 1061 IGQNC-DRCAPNTWQLASGTGCDP-CNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-EC 1117
Query: 482 PPGTWG---FSCNASCQCAHEAVCSPQ----TGACTCTPGWHGAHCQLPCPKGQFGEGCA 534
WG C A C C + +PQ TG C C G G C C +G G
Sbjct: 1118 QELFWGDPDVECRA-CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSGV--- 1172
Query: 535 SRCDCDHSDGCDPVHGRCQCQAGW 558
C P H QC A W
Sbjct: 1173 -------FPDCTPCH---QCFALW 1186
Score = 133 bits (334), Expect = 1e-30
Identities = 104/352 (29%), Positives = 135/352 (38%), Gaps = 78/352 (22%)
Query: 451 CSCEN----AIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFS------CNASCQCAHEA 500
C C+ + C P G+C C+ C+ C PGT+GF C Q + A
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCN-RCAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 501 VCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCD-HSDGCDPVHGRC-QCQAGW 558
C+P TG C C G + C C G +G C C+ H+D CDPV G C CQ
Sbjct: 832 FCNPVTGQCHCFQGVYARQCD-RCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYT 890
Query: 559 MGARCHLSCPEGLWG------VNCSNTCTCKNGGTCLPENGN----------------CV 596
MG C C G +G + C C +G P++G CV
Sbjct: 891 MGHNCE-RCLAGYYGDPIIGSGDHCRPCPCPDG----PDSGRQFARSCYQDPVTLQLACV 945
Query: 597 CAPGFRGPSCQRSC-----QPGRYGKRCVPCKCANH------SFCHPSNGTCY-CLAGWT 644
C PG+ G C P G C PC+C N+ C G C CL
Sbjct: 946 CDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTE 1005
Query: 645 GPDCSQPCPPGHWGENCAQTCQ---CHHGGT-----------CHPQDGSCICPLGWTGHH 690
G C Q C G++G+ Q C+ C++ GT C G C+C G +
Sbjct: 1006 GEHC-QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQN 1064
Query: 691 CLEGCPLGTF----GANCSQPCQCGP----GEKCHPETGACVCPPGHSGAPC 734
C + C T+ G C PC C G C+ TG C C PG G C
Sbjct: 1065 C-DRCAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTC 1114
Score = 129 bits (324), Expect = 1e-29
Identities = 114/397 (28%), Positives = 148/397 (37%), Gaps = 113/397 (28%)
Query: 143 QCDKPCSCGNNSSCDPKSGVCSC--------------------PSGLQPPNC-------- 174
+CD S +S CDP G C C PSG +P C
Sbjct: 774 ECDPQGSL--SSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 175 -------------------LQPCTPGYYG-PACQFRCQC--HGAPCDPQTGACF-CPAER 211
C PG++G P+CQ CQC H CDP TG C C
Sbjct: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQ-PCQCNGHADDCDPVTGECLNCQDYT 890
Query: 212 TGPSC---------DVSCSQGTSGFFCPSTHSCQNGGVFQ--------TPQGSCSCPPGW 254
G +C D G CP +G F T Q +C C PG+
Sbjct: 891 MGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGY 950
Query: 255 MGTICSLPCPEGFHG-----PNCSQECRCHNG------GLCDRFTGQC-RCAPGYTGDRC 302
+G+ C C G+ G Q C+CHN CD+ TG+C +C G+ C
Sbjct: 951 IGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC 1009
Query: 303 REECPVGRFG----QDCAETCDC-----------APDARCFPANGACLCEHGFTGDRCTD 347
+ C G +G QDC + C C D +C A G CLC G C D
Sbjct: 1010 -QFCRFGYYGDALQQDCRK-CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNC-D 1066
Query: 348 RLCPDGFY---GLSCQAPCTCDREHSL--SCHPMNGECSCLPGWAGLHCNESCPQDTHGP 402
R P+ + G C PC C+ HS SC+ G+C C+PG+ G C+E P
Sbjct: 1067 RCAPNTWQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDP 1125
Query: 403 GCQ-EHCLCLHGGV----CQATSGLCQCAPGYTGPHC 434
+ C C G+ C ++G C C G GP C
Sbjct: 1126 DVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRC 1162
Score = 108 bits (269), Expect = 3e-23
Identities = 90/303 (29%), Positives = 114/303 (37%), Gaps = 62/303 (20%)
Query: 487 GFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG---EGCASRCDCDHSD 543
G +C Q + +VC P G C C P G C C G FG GC C+C H
Sbjct: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCN-RCAPGTFGFGPSGC-KPCEC-HLQ 826
Query: 544 G-----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCK-NGGTCLPENGNCV- 596
G C+PV G+C C G +C C G WG C C + C P G C+
Sbjct: 827 GSVNAFCNPVTGQCHCFQGVYARQCD-RCLPGHWGFPSCQPCQCNGHADDCDPVTGECLN 885
Query: 597 CAPGFRGPSCQRSCQPGRY-------GKRCVPCKC-----ANHSF---CHPSNGT----C 637
C G +C+R C G Y G C PC C + F C+ T C
Sbjct: 886 CQDYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
Query: 638 YCLAGWTGPDCSQPCPPGHWGE-----NCAQTCQCHHG------GTCHPQDGSCI-CPLG 685
C G+ G C C G++G Q CQCH+ C + G C+ C
Sbjct: 945 VCDPGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYH 1003
Query: 686 WTGHHCLEGCPLGTFGANCSQPC-QC-------------GPGEKCHPETGACVCPPGHSG 731
G HC + C G +G Q C +C G +C TG C+C P G
Sbjct: 1004 TEGEHC-QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIG 1062
Query: 732 APC 734
C
Sbjct: 1063 QNC 1065
Score = 100 bits (248), Expect = 9e-21
Identities = 89/308 (28%), Positives = 120/308 (38%), Gaps = 80/308 (25%)
Query: 83 DHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGP 142
DH + C G R F A+ C C C PG+ G C +CA G +G
Sbjct: 912 DHCRPCPCPDGPDSGRQF-----ARSCYQDPVTLQLACVCDPGYIGSRCD-DCASGYFGN 965
Query: 143 QCD-----KPCSCGNN------SSCDPKSGVC-SCPSGLQPPNCLQPCTPGYYGPACQFR 190
+ +PC C NN +CD ++G C C + +C Q C GYYG A Q
Sbjct: 966 PSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC-QFCRFGYYGDALQQD 1024
Query: 191 CQ-------------CHGAPC--DPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSC 235
C+ C+G+ C D TG C C G +CD C+ T
Sbjct: 1025 CRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCD-RCAPNT----------- 1072
Query: 236 QNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAP 295
+Q G+ C P C+ F GP+C++ FTGQC+C P
Sbjct: 1073 -----WQLASGT-GCDP------CNCNAAHSF-GPSCNE------------FTGQCQCMP 1107
Query: 296 GYTGDRCREECPVGRFGQDCAE--TCDCAP----DARCFPANGACLCEHGFTGDRCTDRL 349
G+ G C EC +G E CDC P +C + G C+C G G RC
Sbjct: 1108 GFGGRTC-SECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK-- 1164
Query: 350 CPDGFYGL 357
C G+ G+
Sbjct: 1165 CTRGYSGV 1172
Score = 71.2 bits (173), Expect = 5e-12
Identities = 79/305 (25%), Positives = 104/305 (34%), Gaps = 86/305 (28%)
Query: 148 CSC-GNNSSCDPKSGV-----------CSCPSGLQPPNCLQPCTPGYY-----------G 184
C C G+ S C P G C C + NC + C Y+
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNC-ELCMDFYHDLPWRPAEGRNS 329
Query: 185 PACQFRCQC--HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQ 242
AC+ +C C H C +G CD C T G C +Q
Sbjct: 330 NACK-KCNCNEHSISCHFDMAVYLATGNVSGGVCD-DCQHNTMGRNCEQCKPFY----YQ 383
Query: 243 TPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRC-----HNGGLCDRFT--------G 289
P+ PN + C C N G+CD +T G
Sbjct: 384 HPE-------------------RDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAG 424
Query: 290 QCRCAPGYTGDRCREECPVGRFGQDCAE-----TCDCAPDAR------CFPANGACLCEH 338
QCRC G+ C + C G + + +C C P C G C C+
Sbjct: 425 QCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKR 483
Query: 339 GFTGDRCTDRLCPDGFYGLS-----CQAPCTCDREHSL--SCHPMNGECSCLPGWAGLHC 391
TG C D+ P+ +GLS C+ PC CD +L SC +G+CSC P G C
Sbjct: 484 LVTGQHC-DQCLPE-HWGLSNDLDGCR-PCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
Query: 392 NESCP 396
NE P
Sbjct: 541 NEVEP 545
Score = 68.2 bits (165), Expect = 4e-11
Identities = 64/253 (25%), Positives = 92/253 (36%), Gaps = 70/253 (27%)
Query: 331 NGACLCEHGFTGDRCTDRLCPDGFYGL-----------SCQAPCTCDREHSLSCH----- 374
+G C+C H G C LC D ++ L +C+ C C+ EHS+SCH
Sbjct: 295 HGHCMCRHNTKGLNC--ELCMDFYHDLPWRPAEGRNSNACKK-CNCN-EHSISCHFDMAV 350
Query: 375 ------PMNGECS-CLPGWAGLHCNESCP-------QDTHGPGCQEHCLC-----LHGGV 415
G C C G +C + P +D P E C C + G+
Sbjct: 351 YLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGI 410
Query: 416 CQA--------TSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPID---- 463
C + +G C+C G HC +C Y ++ C++ AC+P+
Sbjct: 411 CDSYTDFSTGLIAGQCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCKSC-ACNPLGTIPG 468
Query: 464 --------GECVCKEGWQRGNCSVPCPPGTWGFSCNAS----CQC----AHEAVCSPQTG 507
G C CK +C C P WG S + C C A C ++G
Sbjct: 469 GNPCDSETGHCYCKRLVTGQHCD-QCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESG 527
Query: 508 ACTCTPGWHGAHC 520
C+C P G C
Sbjct: 528 QCSCRPHMIGRQC 540
Score = 65.1 bits (157), Expect = 3e-10
Identities = 67/291 (23%), Positives = 95/291 (32%), Gaps = 81/291 (27%)
Query: 443 YGVNCSARCSCE-NAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAV 501
Y + C C +A C+P+DG EG G+C C T G +C H+
Sbjct: 263 YDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCM--CRHNTKGLNCELCMDFYHDLP 320
Query: 502 CSPQTG----AC-TCTPGWHGAHCQL-----------------PCPKGQFGEGC------ 533
P G AC C H C C G C
Sbjct: 321 WRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPF 380
Query: 534 --------------ASRCDCDHSDG-----CDP--------VHGRCQCQAGWMGARCHLS 566
RC CD + CD + G+C+C+ G C +
Sbjct: 381 YYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDV- 439
Query: 567 CPEGLWGVNCSNTCTCKN-----------GGTCLPENGNCVCAPGFRGPSCQRSCQPGRY 615
C EG + ++ + CK+ G C E G+C C G C + C P +
Sbjct: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ-CLPEHW 498
Query: 616 G-----KRCVPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHW 657
G C PC C A ++ C +G C C G C++ PG++
Sbjct: 499 GLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNE-VEPGYY 548
Score = 63.9 bits (154), Expect = 7e-10
Identities = 61/257 (23%), Positives = 84/257 (32%), Gaps = 70/257 (27%)
Query: 246 GSCSCPPGWMGTICSLPCPEGFH----------GPNCSQECRCHNGGLCDRFTGQCRCAP 295
G C C G C L C + +H N ++C C+ + F A
Sbjct: 296 GHCMCRHNTKGLNCEL-CMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 296 GYTGDRCREECPVGRFGQDC--------------------AETCDCAP------------ 323
G ++C G++C E C C P
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSY 414
Query: 324 -DARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMN----- 377
D G C C+ G+ C +C +GFY LS + P C S +C+P+
Sbjct: 415 TDFSTGLIAGQCRCKLNVEGEHCD--VCKEGFYDLSSEDPFGCK---SCACNPLGTIPGG 469
Query: 378 -------GECSCLPGWAGLHCNESCPQ----DTHGPGCQEHCLCLHGGV----CQATSGL 422
G C C G HC++ P+ GC+ C C GG C A SG
Sbjct: 470 NPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRP-CDCDLGGALNNSCFAESGQ 528
Query: 423 CQCAPGYTGPHCASLCP 439
C C P G C + P
Sbjct: 529 CSCRPHMIGRQCNEVEP 545
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/198 (25%), Positives = 65/198 (32%), Gaps = 57/198 (28%)
Query: 592 NGNCVCAPGFRGPSCQRSCQ----------PGRYGKRCVPCKCANHSF-CH--------- 631
+G+C+C +G +C+ GR C C C HS CH
Sbjct: 295 HGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 632 --PSNGTC-YCLAGWTGPDCSQPCPPGHW--------GENCAQTCQC-----HHGGTCHP 675
S G C C G +C Q C P ++ N + C C + G C
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQ-CKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413
Query: 676 QD--------GSCICPLGWTGHHCLEGCPLGTFGANCSQP-----CQCGP------GEKC 716
G C C L G HC + C G + + P C C P G C
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPC 472
Query: 717 HPETGACVCPPGHSGAPC 734
ETG C C +G C
Sbjct: 473 DSETGHCYCKRLVTGQHC 490
Score = 47.0 bits (110), Expect = 9e-05
Identities = 46/181 (25%), Positives = 65/181 (35%), Gaps = 31/181 (17%)
Query: 108 ECVHGRCVAPNQCQCVPGW--------RGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPK 159
+C H + N QC P + R + C G Q + C + S
Sbjct: 364 DCQHNT-MGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLI 422
Query: 160 SGVCSCPSGLQPPNCLQPCTPGYYGPACQF-----RCQCH-------GAPCDPQTGACFC 207
+G C C ++ +C C G+Y + + C C+ G PCD +TG C+C
Sbjct: 423 AGQCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYC 481
Query: 208 PAERTGPSCDVSCSQ--GTSGFF--CPSTHSCQNGGVFQ----TPQGSCSCPPGWMGTIC 259
TG CD + G S C C GG G CSC P +G C
Sbjct: 482 KRLVTGQHCDQCLPEHWGLSNDLDGCRPC-DCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
Query: 260 S 260
+
Sbjct: 541 N 541
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 143 bits (360), Expect = 1e-33
Identities = 173/761 (22%), Positives = 261/761 (34%), Gaps = 200/761 (26%)
Query: 91 CHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSC 150
C G ++ F C ++ + N C W + + E C CSC
Sbjct: 493 CQGVIDAYFFLAANCTEDATYVNDPEDNNSSC---WFPHEGTKEI--------CANGCSC 541
Query: 151 ------------------GN---NSSCDPKSGVCS----CPSGLQPPNCLQPCTPGYYGP 185
GN ++ D + C C + P C C+ Y G
Sbjct: 542 LSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRC--SCSLSYIGR 599
Query: 186 ACQFRCQ-CHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP------STHSCQNG 238
C C G G C + +C+ S Q C + SC+NG
Sbjct: 600 LCVVNVDYCLGNHSISVHGLCLALSH----NCNCSGLQRYERNICEIDTEDCKSASCKNG 655
Query: 239 GVFQTPQGSC--SCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQ------ 290
+G C PG+ GT C + E P C NG C G
Sbjct: 656 TTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHP-------CKNGATCIDQPGNYFCQCV 708
Query: 291 ----------CRCAPGYTGDRCREECPVGRFGQDCA-ETCDCAPDARCFPANGACLCEHG 339
C C PGY G RC ++ DC C+ + + C+C
Sbjct: 709 PPFKVVDGFSCLCNPGYVGIRCEQDI------DDCILNACEHNSTCKDLHLSYQCVCLSD 762
Query: 340 FTGDRCTDRLCPDGFYGLSCQA-PCTCDREHSLSCHPM--NGECSCLPGWAGLHCNESCP 396
+ G+ C C+ PC +++ +C + + C C GW G +C+E
Sbjct: 763 WEGNFCEQE-------SNECKMNPC----KNNSTCTDLYKSYRCECTSGWTGQNCSEEIN 811
Query: 397 QDTHGPGCQEHCLCLHGGVCQATS----GLCQCAPGYTGPHCA---SLCPPDTYGVNCSA 449
+ P C++GG+C ++ +C C P YTG C +LC D C
Sbjct: 812 ECDSDP-------CMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC--DLLHNPCRN 862
Query: 450 RCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGAC 509
+C +A + C+C+E ++ NC + + SCQ + C
Sbjct: 863 NSTC---LALVDANQHCICREEFEGKNCEIDVKDCLF-----LSCQDYGDCEDMVNNFRC 914
Query: 510 TCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGR--CQCQAGWMGARCHLSC 567
C PG+ G+ C++ + C+S C ++ C + R C C+ + G C L
Sbjct: 915 ICRPGFSGSLCEIEINE------CSSE-PCKNNGTCVDLTNRFFCNCEPEYHGPFCELD- 966
Query: 568 PEGLWGVNCSNTCTCKNGGTCL--PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCA 625
VN C + C+ + NC+CAPG+ G +C+ + C+ C
Sbjct: 967 ------VNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLD------ECLSEPCL 1014
Query: 626 NHSFCHP--SNGTCYCLAGWTGPDC--------SQPCPPGHWGE---------------- 659
+ C ++ TC C +G+ G C S PC G E
Sbjct: 1015 HDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTST 1074
Query: 660 ------NCAQTCQCHHGGTCHPQDG--SCICPLGWTGHHCLEGCPLGTFGANCSQP---- 707
N + C + G C +CICP G+TG +C + NC++P
Sbjct: 1075 QCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSID------NCAEPELNS 1128
Query: 708 --------CQCGPGEKCHPETGACVCPPGHSGAPCRIGIQE 740
C GPG T C C PG SG C I I E
Sbjct: 1129 VICLNGGICVDGPGH-----TFDCRCLPGFSGQFCEININE 1164
Score = 118 bits (296), Expect = 3e-26
Identities = 129/526 (24%), Positives = 180/526 (34%), Gaps = 165/526 (31%)
Query: 119 QCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDP--KSGVCSCPSGLQPPNCLQ 176
QC C+ W G+ C E P C NNS+C KS C C SG NC +
Sbjct: 756 QCVCLSDWEGNFCEQESNECKMNP-------CKNNSTCTDLYKSYRCECTSGWTGQNCSE 808
Query: 177 P---------------------------CTPGYYGPACQFR---CQCHGAPCDPQTGA-- 204
C P Y G C R C PC +
Sbjct: 809 EINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLA 868
Query: 205 -------CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS--CSCPPGWM 255
C C E G +C++ C SCQ+ G + + C C PG+
Sbjct: 869 LVDANQHCICREEFEGKNCEIDVKD------CLFL-SCQDYGDCEDMVNNFRCICRPGFS 921
Query: 256 GTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQ--CRCAPGYTGDRCREECPVGRFGQ 313
G++C + E CS E C N G C T + C C P Y G C E V +
Sbjct: 922 GSLCEIEINE------CSSE-PCKNNGTCVDLTNRFFCNCEPEYHGPFC--ELDVNK--- 969
Query: 314 DCAETCDCAPDARC-FPANG-ACLCEHGFTGDRCTDRL---------------------- 349
+ C + C + +G CLC G+TG C L
Sbjct: 970 --CKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYT 1027
Query: 350 --CPDGFYGLSCQA----------------------PCTCDRE-HSLSCHPMNGECSCLP 384
C GF+G C+ PC+CD + S C +C+ +P
Sbjct: 1028 CDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIP 1087
Query: 385 GWAGLHCNES-------CPQDTHGPGCQ---EHC--------LCLHGGVCQATSGL---C 423
C +S CP+ G C+ ++C +CL+GG+C G C
Sbjct: 1088 CMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDC 1147
Query: 424 QCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSP-IDG-ECVCKEGWQRGNC--SV 479
+C PG++G C +N + C + C I+G C C+ GW +C +
Sbjct: 1148 RCLPGFSGQFC-------EININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL 1200
Query: 480 PCPPGTWGFSCNASCQCAHEAVCSPQTGA-CTCTPGWHGAHCQLPC 524
C P + C HE + G+ C CTPG+ L C
Sbjct: 1201 ECIPNS----------CVHELCMENEPGSTCLCTPGFMTCSIGLLC 1236
Score = 117 bits (293), Expect = 6e-26
Identities = 134/519 (25%), Positives = 181/519 (34%), Gaps = 128/519 (24%)
Query: 119 QCQCVPGWRGDDCSSECAPGMWGPQCDK-PCSCGN--NSSCDPKSGVCSCPSGLQPPNCL 175
+C+C GW G +CS E +CD PC G + S P VC CP
Sbjct: 794 RCECTSGWTGQNCSEEIN------ECDSDPCMNGGLCHESTIPGQFVCLCP--------- 838
Query: 176 QPCTPGYYGPACQFR---CQCHGAPCDPQTGA---------CFCPAERTGPSCDVSCSQG 223
P Y G C R C PC + C C E G +C++
Sbjct: 839 ----PLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKD- 893
Query: 224 TSGFFCPSTHSCQNGGVFQTPQGS--CSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNG 281
C SCQ+ G + + C C PG+ G++C + E CS E C N
Sbjct: 894 -----CLFL-SCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINE------CSSE-PCKNN 940
Query: 282 GLCDRFTGQ--CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARC-FPANGA-CLCE 337
G C T + C C P Y G C E V + + C + C + +G CLC
Sbjct: 941 GTCVDLTNRFFCNCEPEYHGPFC--ELDVNK-----CKISPCLDEENCVYRTDGYNCLCA 993
Query: 338 HGFTGDRCT-------------DRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGEC---S 381
G+TG C D +C DG +C H C +C
Sbjct: 994 PGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTH---CETNANDCLSNP 1050
Query: 382 CLPGWAGLHCNE---SCPQDTHGPGCQ---EHCL---CLHGGVCQATSG--LCQCAPGYT 430
CL G NE SC D C+ C C++ G CQ ++ C C GYT
Sbjct: 1051 CLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYT 1110
Query: 431 GPHCA----SLCPPDTYGVNCSARCSCENAIACSPIDG-----ECVCKEGWQRGNCSVPC 481
G +C + P+ V C C +DG +C C G+ C +
Sbjct: 1111 GAYCEKSIDNCAEPELNSVICLNGGIC--------VDGPGHTFDCRCLPGFSGQFCEINI 1162
Query: 482 PPGTWGFSCNASCQCAHEAVCSPQTGA--CTCTPGWHGAHC--QLPCPKGQFGEGCASRC 537
C++S C H A C C C PGW G HC +L C C
Sbjct: 1163 N------ECSSS-PCLHGADCEDHINGYVCKCQPGWSGHHCENELEC----IPNSCVHEL 1211
Query: 538 DCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNC 576
++ G C C G+M L C + + + C
Sbjct: 1212 CMENEPG-----STCLCTPGFMTCSIGLLCGDEIRRITC 1245
Score = 104 bits (260), Expect = 4e-22
Identities = 176/753 (23%), Positives = 238/753 (31%), Gaps = 193/753 (25%)
Query: 119 QCQCVPGWRGDDCSS---ECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNC- 174
+C C P + G +CS +C P + C GN S+ S +C C P C
Sbjct: 241 ECVCHPPFTGKNCSEIIGQCQPHV--------CFHGNCSNITSNSFICECDEQFSGPFCE 292
Query: 175 --LQPCTPGYYGP--ACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP 230
+PC + C + C P+ + V C GT
Sbjct: 293 VSAKPCVSLLFWKRGICPNSSSAYTYEC-PKGSSSQNGETDVSEFSLVPCQNGTDCIKIS 351
Query: 231 STHSCQNGGVF-----QTPQGSCSCPPGWMGTICS-------LPCPEGFHGPNCSQ---E 275
+ C +F ++ Q SC P C C GF NC +
Sbjct: 352 NDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDH 411
Query: 276 CR-----CHNGGLCDRFTGQCR--CAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCF 328
C+ C N C G+ + C PG T + C V Q C C
Sbjct: 412 CKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQ---HLCYCGVTFHGI 468
Query: 329 -----PANGACLCEHGFT---GDRCTDRLCPDGFYGLSCQAPCTC---DREHSLSC-HPM 376
PA + + GF G++C + F +C T +++ SC P
Sbjct: 469 CQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPH 528
Query: 377 NGE-------CSCLP-------------GWAGLHCNESCPQDTHGPGCQEHCLCLHGGVC 416
G CSCL WAG E+ D C H VC
Sbjct: 529 EGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENE-------CQHEAVC 581
Query: 417 --QATSGLCQCAPGYTGPHCA---------------SLCPPDTYGVNCSARCSCENAIAC 459
+ C C+ Y G C LC ++ NCS E I C
Sbjct: 582 KDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNI-C 640
Query: 460 SPIDGEC---VCKEGWQ----RGNCSVPCPPGTWGFSCN------ASCQCAHEAVCSPQT 506
+C CK G RG C PG G C AS C + A C Q
Sbjct: 641 EIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQP 700
Query: 507 G----------------ACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVH- 549
G +C C PG+ G C+ Q + C C+H+ C +H
Sbjct: 701 GNYFCQCVPPFKVVDGFSCLCNPGYVGIRCE------QDIDDCILNA-CEHNSTCKDLHL 753
Query: 550 -GRCQCQAGWMGARCHLSCPEGLWGVNCSNTC---TCKNGGTC--LPENGNCVCAPGFRG 603
+C C + W G C SN C CKN TC L ++ C C G+ G
Sbjct: 754 SYQCVCLSDWEGNFCEQE----------SNECKMNPCKNNSTCTDLYKSYRCECTSGWTG 803
Query: 604 PSCQRSCQPGRYGKRCVPCKCANHSFCHPSN--GTCYCLAGWTGPDCSQPCPPGHWGENC 661
+C C C N CH S G CL CPP + G+ C
Sbjct: 804 QNCSEEI------NECDSDPCMNGGLCHESTIPGQFVCL-----------CPPLYTGQFC 846
Query: 662 AQTCQ--------CHHGGTC---HPQDGSCICPLGWTGHHC---LEGCPLGTFGANCSQP 707
Q C + TC + CIC + G +C ++ C +C
Sbjct: 847 HQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC----LFLSCQDY 902
Query: 708 CQCGPGEKCHPETGACVCPPGHSGAPCRIGIQE 740
C + C+C PG SG+ C I I E
Sbjct: 903 GDC----EDMVNNFRCICRPGFSGSLCEIEINE 931
Score = 93.6 bits (231), Expect = 9e-19
Identities = 161/707 (22%), Positives = 224/707 (31%), Gaps = 156/707 (22%)
Query: 150 CGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPC----------- 198
C + S + SG C S C P + G CQ C PC
Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233
Query: 199 --DPQTGACFCPAERTGPSCDV-------------SCSQGTSGFFCPSTHSCQNGGVFQT 243
D Q C C TG +C +CS TS F +G +
Sbjct: 234 NWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEV 293
Query: 244 PQGSCSCPPGWMGTIC-------SLPCPEGFHGPNCSQECR------CHNGGLCDRFTG- 289
C W IC + CP+G N + C NG C + +
Sbjct: 294 SAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISND 353
Query: 290 -QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARC--FPANGACLCEHGFTGDRCT 346
C C+P +T C+ Q E+ +A C + C C GFT C
Sbjct: 354 VMCICSPIFTDLLCKSI-------QTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
Query: 347 DRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQE 406
+ ++C C + C+ P W L Q G
Sbjct: 407 KAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWF-LKNVYLIHQHLCYCGVTF 465
Query: 407 HCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGEC 466
H +C G Q G G C + D Y +A C+ + P D
Sbjct: 466 HGICQDKGPAQFEYVWQLGFAGSEGEKCQGVI--DAY-FFLAANCTEDATYVNDPEDNNS 522
Query: 467 VC-------KEGWQRG-NCSVPCPPGTWGFSC---------------NASCQCAHEAVCS 503
C KE G +C + + C + +C HEAVC
Sbjct: 523 SCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCK 582
Query: 504 PQTG--ACTCTPGWHGAHCQLP---------------CPKGQFGEGCA-------SRCDC 539
+ C+C+ + G C + C C+ + C+
Sbjct: 583 DEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEI 642
Query: 540 DHSD--------GCDPVHGR----CQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGT 587
D D G H R +C G+ G +C + E C++ CKNG T
Sbjct: 643 DTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDE------CASH-PCKNGAT 695
Query: 588 CLPENGN--CVCAPGFR---GPSCQRSCQPGRYGKR-------CVPCKCANHSFCHPSNG 635
C+ + GN C C P F+ G SC C PG G R C+ C ++S C +
Sbjct: 696 CIDQPGNYFCQCVPPFKVVDGFSC--LCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHL 753
Query: 636 T--CYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHP--QDGSCICPLGWTGHHC 691
+ C CL+ W G C Q N + C + TC + C C GWTG +C
Sbjct: 754 SYQCVCLSDWEGNFCEQE-------SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC 806
Query: 692 LEGCPLGTFGANCSQPCQCGPGEKCH----PETGACVCPPGHSGAPC 734
E S PC G CH P C+CPP ++G C
Sbjct: 807 SE-----EINECDSDPCM--NGGLCHESTIPGQFVCLCPPLYTGQFC 846
Score = 51.2 bits (121), Expect = 5e-06
Identities = 143/631 (22%), Positives = 196/631 (31%), Gaps = 185/631 (29%)
Query: 246 GSCSCPPGWM--GTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCR 303
G CP G T+ C E CS +C + ++ C C P ++G C+
Sbjct: 155 GPSPCPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYS--CHCQPPFSGKYCQ 212
Query: 304 EECPVGRFGQDCAETCDCAPDARCFPANG-------ACLCEHGFTGDRCTD-------RL 349
E D C + C C+C FTG C++ +
Sbjct: 213 E--------LDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHV 264
Query: 350 CPDGFYG-----LSCQAPCTCDREHS-LSCHPMNGECSCLPGWAGLHCNES-------CP 396
C F+G S C CD + S C C L W C S CP
Sbjct: 265 C---FHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECP 321
Query: 397 QDTHGPG----CQEHCL--CLHGGVCQATSG--LCQCAPGYTGPHCASL-CPPDTYGVNC 447
+ + E L C +G C S +C C+P +T C S+ +++ +
Sbjct: 322 KGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRN 381
Query: 448 SARC-SCENAIACSPIDGECVCKEGWQRGNC----------SVPCPPGTWGFSCNASCQC 496
+A C CE D C C G+ NC S+ C W F+
Sbjct: 382 NATCKKCEK-------DYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIG---- 430
Query: 497 AHEAVCSPQTGACTCTPGW-------------------HGAHCQLPCP-----------K 526
+ VC P CT P W HG CQ P
Sbjct: 431 RFKYVCIP---GCTKNPCWFLKNVYLIHQHLCYCGVTFHGI-CQDKGPAQFEYVWQLGFA 486
Query: 527 GQFGEGC----------ASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNC 576
G GE C A+ C D + DP C G + C
Sbjct: 487 GSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK-----------EIC 535
Query: 577 SNTCTCKN---------------GGTCLPEN----------GNCVCAPGFRGPSCQRSCQ 611
+N C+C + G EN VC P C SC
Sbjct: 536 ANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRC--SCS 593
Query: 612 PGRYGKRCVPCKCANHSFC---HPSNGTCYCLAGWTGPDCS-------QPCPPGHWGENC 661
G+ CV N +C H + CLA +CS C E+C
Sbjct: 594 LSYIGRLCV----VNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEID--TEDC 647
Query: 662 AQTCQCHHGGTCHPQDGSCI--CPLGWTGHHC---LEGCPLGTF--GANC-SQP----CQ 709
++ C +G T G C G+ G C ++ C GA C QP CQ
Sbjct: 648 -KSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQ 706
Query: 710 CGPGEKCHPETGACVCPPGHSGAPCRIGIQE 740
C P K + +C+C PG+ G C I +
Sbjct: 707 CVPPFKV-VDGFSCLCNPGYVGIRCEQDIDD 736
Score = 47.4 bits (111), Expect = 7e-05
Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 12/80 (15%)
Query: 619 CVPCKCANHSFCHPSNGT--CYCLAGWTGPDCSQP---CPPGHWGENCAQTCQCHHGGTC 673
C KC N C S + C C GW G C++ C P H + C G TC
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATC 2668
Query: 674 H--PQDGSCICPLGWTGHHC 691
P +C CPLG TG +C
Sbjct: 2669 ISLPHGYTCFCPLGTTGIYC 2688
Score = 44.7 bits (104), Expect = 5e-04
Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 19/98 (19%)
Query: 600 GFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGT---CYCLAGWTGPDCSQPCPPGH 656
G +G S C G C C N C NGT C CL W G C+Q
Sbjct: 2864 GAKGGSNVGDCD----GTACGYNTCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSV---- 2914
Query: 657 WGENCAQTCQCHHGGTCHPQDG---SCICPLGWTGHHC 691
+C C H C P SC+C LGW G +C
Sbjct: 2915 ---SCLNNL-CLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
Score = 44.7 bits (104), Expect = 5e-04
Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 14/74 (18%)
Query: 581 TCKNGGTCLPENG---NCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNG-- 635
TC+NGG C NG +C C P + G +C +S C+ C + S C P
Sbjct: 2883 TCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSVS-------CLNNLCLHQSLCIPDQSFS 2934
Query: 636 -TCYCLAGWTGPDC 648
+C C GW G C
Sbjct: 2935 YSCLCTLGWVGRYC 2948
Score = 43.9 bits (102), Expect = 8e-04
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 13/73 (17%)
Query: 582 CKNGGTCLPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGT--- 636
C+N GTC+ +N N C C + G CQ + C C N + C P +GT
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFA--------SCENNPCGNGATCVPKSGTDIV 2395
Query: 637 CYCLAGWTGPDCS 649
C C G +GP C+
Sbjct: 2396 CLCPYGRSGPLCT 2408
Score = 43.5 bits (101), Expect = 0.001
Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 11/74 (14%)
Query: 364 TCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVC---QATS 420
TC + + C CLP WAG CN+S C + LCLH +C Q+ S
Sbjct: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-------SCLNN-LCLHQSLCIPDQSFS 2934
Query: 421 GLCQCAPGYTGPHC 434
C C G+ G +C
Sbjct: 2935 YSCLCTLGWVGRYC 2948
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 26/99 (26%)
Query: 84 HRQRLQCCHGFYESRGFCVPLCAQECV--HGRCVAPNQ---CQCVPGWRGDDCSSECAPG 138
H + ++ CH VP CA +G C++ N+ C+C + G C
Sbjct: 2327 HGKNIENCH---------VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA---- 2373
Query: 139 MWGPQCDKPCSCGNNSSCDPKSG---VCSCPSGLQPPNC 174
C+ CGN ++C PKSG VC CP G P C
Sbjct: 2374 ----SCENN-PCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 8/82 (9%)
Query: 666 QCHHGGTCHPQDGS--CICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKC--HPETG 721
+C +GGTC S C C GW G C E + T P C G C P
Sbjct: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTE--TVSTCDPEHDPPHHCSRGATCISLPHGY 2675
Query: 722 ACVCPPGHSGAPCR--IGIQEP 741
C CP G +G C + I +P
Sbjct: 2676 TCFCPLGTTGIYCEQALSISDP 2697
Score = 42.0 bits (97), Expect = 0.003
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 22/103 (21%)
Query: 556 AGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGN---CVCAPGFRGPSCQRS--- 609
AG +CH S CS C NGGTC+ E+G C C G++G C +
Sbjct: 2602 AGRSVGQCHAS--------PCS-LMKCGNGGTCI-ESGTSVYCNCTTGWKGSFCTETVST 2651
Query: 610 CQPGRYGKRCVPCKCANHSFCH--PSNGTCYCLAGWTGPDCSQ 650
C P + P C+ + C P TC+C G TG C Q
Sbjct: 2652 CDP----EHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 41.2 bits (95), Expect = 0.005
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 15/90 (16%)
Query: 265 EGFHGPNCSQECRCHNGGLC--DRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCA 322
E H P C+ C N G C D C C Y+G C+ E C
Sbjct: 2332 ENCHVPWCAHHL-CRNNGTCISDNENLFCECPRLYSGKLCQFAS---------CENNPCG 2381
Query: 323 PDARCFPANGA---CLCEHGFTGDRCTDRL 349
A C P +G CLC +G +G CTD +
Sbjct: 2382 NGATCVPKSGTDIVCLCPYGRSGPLCTDAI 2411
Score = 40.4 bits (93), Expect = 0.009
Identities = 34/104 (32%), Positives = 48/104 (46%), Gaps = 23/104 (22%)
Query: 614 RYGKRCVPCK---CANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCA-QTCQ--- 666
R+GK C CA+H C +NGTC + CP + G+ C +C+
Sbjct: 2326 RHGKNIENCHVPWCAHH-LCR-NNGTCIS----DNENLFCECPRLYSGKLCQFASCENNP 2379
Query: 667 CHHGGTCHPQDGS---CICPLGWTGHHCLEGCPLGTFGANCSQP 707
C +G TC P+ G+ C+CP G +G PL T N +QP
Sbjct: 2380 CGNGATCVPKSGTDIVCLCPYGRSG-------PLCTDAINITQP 2416
Score = 40.0 bits (92), Expect = 0.011
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 7/73 (9%)
Query: 278 CHNGGLC--DRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACL 335
C NGG C + T CRC P + G+ C + V C C PD + +CL
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQS--VSCLNNLCLHQSLCIPDQ---SFSYSCL 2938
Query: 336 CEHGFTGDRCTDR 348
C G+ G C ++
Sbjct: 2939 CTLGWVGRYCENK 2951
Score = 38.1 bits (87), Expect = 0.043
Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 23/77 (29%)
Query: 150 CGNNSSC--DPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR-CQ---C-HGAPCDPQT 202
C NN +C D ++ C CP Y G CQF C+ C +GA C P++
Sbjct: 2344 CRNNGTCISDNENLFCECPRL-------------YSGKLCQFASCENNPCGNGATCVPKS 2390
Query: 203 GA---CFCPAERTGPSC 216
G C CP R+GP C
Sbjct: 2391 GTDIVCLCPYGRSGPLC 2407
Score = 38.1 bits (87), Expect = 0.043
Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 21/85 (24%)
Query: 192 QCHGAPCDPQT----GACFCPAERTGPSCDVSCSQGTSGFFCPST-----------HSCQ 236
QCH +PC G C +G S +C+ G G FC T H C
Sbjct: 2608 QCHASPCSLMKCGNGGTCI----ESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS 2663
Query: 237 NGGV-FQTPQG-SCSCPPGWMGTIC 259
G P G +C CP G G C
Sbjct: 2664 RGATCISLPHGYTCFCPLGTTGIYC 2688
Score = 38.1 bits (87), Expect = 0.043
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 18/73 (24%)
Query: 464 GECVCKEGWQRGNCSVP-------CPPGTWGFSCNASCQCA-----HEAVCSPQTG---A 508
G C+ G G C+V C P G +CN S C H+++C P +
Sbjct: 2880 GYNTCRNG---GECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYS 2936
Query: 509 CTCTPGWHGAHCQ 521
C CT GW G +C+
Sbjct: 2937 CLCTLGWVGRYCE 2949
Score = 37.4 bits (85), Expect = 0.074
Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 15/96 (15%)
Query: 143 QCD-KPCS---CGNNSSC--DPKSGVCSCPSGLQPPNCLQP---CTPGYYGPACQFRCQC 193
QC PCS CGN +C S C+C +G + C + C P + P C
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP---HHCS- 2663
Query: 194 HGAPCD--PQTGACFCPAERTGPSCDVSCSQGTSGF 227
GA C P CFCP TG C+ + S F
Sbjct: 2664 RGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSF 2699
Score = 35.8 bits (81), Expect = 0.22
Identities = 24/84 (28%), Positives = 27/84 (32%), Gaps = 3/84 (3%)
Query: 268 HGPNCSQECRCHNGGLC--DRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDA 325
H CS +C NGG C + C C G+ G C E D C
Sbjct: 2610 HASPCSL-MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC 2668
Query: 326 RCFPANGACLCEHGFTGDRCTDRL 349
P C C G TG C L
Sbjct: 2669 ISLPHGYTCFCPLGTTGIYCEQAL 2692
Score = 35.8 bits (81), Expect = 0.22
Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 120 CQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCD--PKSGVCSCPSGLQPPNCLQ 176
C C GW+G C+ + P+ D P C ++C P C CP G C Q
Sbjct: 2634 CNCTTGWKGSFCTETVS--TCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 33.5 bits (75), Expect = 1.1
Identities = 37/120 (30%), Positives = 45/120 (37%), Gaps = 35/120 (29%)
Query: 490 CNAS----CQCAHEAVC--SPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSD 543
C+AS +C + C S + C CT GW KG F S CD +H
Sbjct: 2609 CHASPCSLMKCGNGGTCIESGTSVYCNCTTGW----------KGSFCTETVSTCDPEH-- 2656
Query: 544 GCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCL-PENGNCVCAPGFR 602
DP H C GA C +S P G TC C G T + E + P FR
Sbjct: 2657 --DPPH-HCS-----RGATC-ISLPHGY-------TCFCPLGTTGIYCEQALSISDPSFR 2700
Score = 33.5 bits (75), Expect = 1.1
Identities = 20/74 (27%), Positives = 26/74 (35%), Gaps = 11/74 (14%)
Query: 493 SCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHG-- 550
+C+ E + T +C C P W G C C + C H C P
Sbjct: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSFS 2934
Query: 551 -RCQCQAGWMGARC 563
C C GW+G C
Sbjct: 2935 YSCLCTLGWVGRYC 2948
Score = 32.7 bits (73), Expect = 1.8
Identities = 19/56 (33%), Positives = 22/56 (39%), Gaps = 13/56 (23%)
Query: 643 WTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHP-------QDGSCICPLGWTGHHC 691
WT S P + Q CH+GGTCH C CPL +TG C
Sbjct: 2090 WTSVSPSVAAP------SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
Score = 32.7 bits (73), Expect = 1.8
Identities = 25/82 (30%), Positives = 32/82 (39%), Gaps = 21/82 (25%)
Query: 233 HSCQNGGVFQTPQG---SCSCPPGWMGTICSLPCPEGFHGPNCSQEC---RCHNGGLC-- 284
++C+NGG T G SC C P W G C N S C C + LC
Sbjct: 2882 NTCRNGGEC-TVNGTTFSCRCLPDWAGNTC-----------NQSVSCLNNLCLHQSLCIP 2929
Query: 285 -DRFTGQCRCAPGYTGDRCREE 305
F+ C C G+ G C +
Sbjct: 2930 DQSFSYSCLCTLGWVGRYCENK 2951
Score = 31.2 bits (69), Expect = 5.3
Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 10/80 (12%)
Query: 231 STHSCQNGGVFQTPQGS--CSCPPGWMGTIC----SLPCPEGFHGPNCSQECRCHNGGLC 284
S C NGG S C+C GW G+ C S PE +CS+ C + L
Sbjct: 2615 SLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS--LP 2672
Query: 285 DRFTGQCRCAPGYTGDRCRE 304
+T C C G TG C +
Sbjct: 2673 HGYT--CFCPLGTTGIYCEQ 2690
Score = 30.4 bits (67), Expect = 9.0
Identities = 18/57 (31%), Positives = 22/57 (38%), Gaps = 4/57 (7%)
Query: 380 CSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQAT--SGLCQCAPGYTGPHC 434
C+C GW G C E+ T P C G C + C C G TG +C
Sbjct: 2634 CNCTTGWKGSFCTETV--STCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYC 2688
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 142 bits (357), Expect = 2e-33
Identities = 153/559 (27%), Positives = 200/559 (35%), Gaps = 133/559 (23%)
Query: 190 RCQCHGAP--CDP--QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ 245
RCQCHG CD Q C C E T G C N F+ Q
Sbjct: 517 RCQCHGHADNCDTTSQPYRCLCSQESF-----------TEGLHCDRCLPLYNDKPFR--Q 563
Query: 246 GSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCH---------NGGLCDRFTGQCRCAPG 296
G + PC H +C GG+CD C
Sbjct: 564 GD------QVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDD------CEHN 611
Query: 297 YTGDRCREECPVGRFGQ--------DCAETCDCAP------DARCFPANGACLCEHGFTG 342
TG C E C F Q D + CDC C G C C+ +G
Sbjct: 612 TTGRNC-ELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSG 670
Query: 343 DRCTDRLCPDGFYGLS------CQAPCTCDR----EHSLSCHPMNGECSCLPGWAGL--- 389
+C C +GFY L C +PC C+ + ++CH +G+C C GL
Sbjct: 671 RQCNQ--CQNGFYNLQELDPDGC-SPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Query: 390 HCNESCP--QDTHGPGCQEHCLC-LHGGV---CQATSGLCQCAPGYTGPHCASLCPPDTY 443
HCN + + GC E C C LHG V C SG C+C G C + C + Y
Sbjct: 728 HCNFGFKFLRSFNDVGC-EPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT-CRENFY 785
Query: 444 GV---NCSARCSCENA-----IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNAS-- 493
G+ NC A C C+ A C+ G+C+CK + C+ C G + N S
Sbjct: 786 GLDVTNCKA-CDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCN-KCLEGNFYLRQNNSFL 843
Query: 494 ---CQCAHEA------VCSPQTGACTCTPGWHGAHCQLPCPKGQFG------EGCASRCD 538
C C +C+ TG C C G G C C ++ + C C+
Sbjct: 844 CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN-QCEPHRYNLTIDNFQHC-QMCE 901
Query: 539 CDHSDG-----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNT-----CTCKNGGT- 587
CD CDP+ G+C C G RC+ C G + ++ N C+C G
Sbjct: 902 CDSLGTLPGTICDPISGQCLCVPNRQGRRCN-QCQPGFY-ISPGNATGCLPCSCHTTGAV 959
Query: 588 ---CLPENGNCVCAPG-FRGPSCQRSCQPGRYG-----KRCVPCKC----ANHSFCHPSN 634
C G CVC G C + C+ +G RC PC C A + CH
Sbjct: 960 NHICNSLTGQCVCQDASIAGQRCDQ-CKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVT 1018
Query: 635 GTCYCLAGWTGPDCSQPCP 653
G C+C TG C P
Sbjct: 1019 GQCFCKQFVTGSKCDACVP 1037
Score = 136 bits (343), Expect = 9e-32
Identities = 149/561 (26%), Positives = 201/561 (35%), Gaps = 145/561 (25%)
Query: 268 HGPNC---SQECRCHNGGLCDR--FTG--QC-RCAPGYTGDRCREECPVGRFGQDCAETC 319
H NC SQ RC LC + FT C RC P Y R+ V F + C
Sbjct: 523 HADNCDTTSQPYRC----LCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN---CKPC 575
Query: 320 DCAPDARC---------FP------ANGACL-CEHGFTGDRCTDRLCPDGFY-------- 355
C ++ FP G C CEH TG C LC D F+
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNC--ELCKDYFFRQVGADPS 633
Query: 356 GLSCQAPCTCD----REHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCL 411
+ PC CD R S+ C + G+C+C +G CN
Sbjct: 634 AIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN------------------- 674
Query: 412 HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEG 471
QC G+ + L P NC+ + + I C G+C CK
Sbjct: 675 ------------QCQNGFY--NLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKAN 720
Query: 472 WQRGNCSVPCPPGTWGFSCNAS--------CQC-AHEAV---CSPQTGACTCTPGWHGAH 519
+ C +GF S CQC H +V C+P +G C C G
Sbjct: 721 V----IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQ 776
Query: 520 CQLPCPKGQFGEGCAS--RCDCDHSDG-----CDPVHGRCQCQAGWMGARCHLSCPEGLW 572
C C + +G + CDCD + C+ G+C C+ G +C+ C EG +
Sbjct: 777 CDT-CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCN-KCLEGNF 834
Query: 573 GVNCSNT-----CTCKNGGT------CLPENGNCVCAPGFRGPSCQRSCQPGRYG----- 616
+ +N+ C C GT C G C C G G C + C+P RY
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQ-CEPHRYNLTIDN 893
Query: 617 -KRCVPCKCAN-----HSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQT----CQ 666
+ C C+C + + C P +G C C+ G C+Q C PG + T C
Sbjct: 894 FQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ-CQPGFYISPGNATGCLPCS 952
Query: 667 CHHGGT----CHPQDGSCICP-LGWTGHHCLEGCPLGTFGANCS----QPCQC----GPG 713
CH G C+ G C+C G C + C FG + QPC C
Sbjct: 953 CHTTGAVNHICNSLTGQCVCQDASIAGQRC-DQCKDHYFGFDPQTGRCQPCNCHLSGALN 1011
Query: 714 EKCHPETGACVCPPGHSGAPC 734
E CH TG C C +G+ C
Sbjct: 1012 ETCHLVTGQCFCKQFVTGSKC 1032
Score = 127 bits (320), Expect = 4e-29
Identities = 141/547 (25%), Positives = 197/547 (36%), Gaps = 109/547 (19%)
Query: 148 CSC-GNNSSCD----PKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQT 202
C C G+ +CD P +CS S + +C C P Y + Q + C P
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHC-DRCLPLYNDKPFRQGDQVYAFNCKP-- 574
Query: 203 GACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLP 262
C C + SC S P H GGV C G C L
Sbjct: 575 --CQCNSHSK------SCHYNISVDPFPFEHFRGGGGVCD------DCEHNTTGRNCEL- 619
Query: 263 CPEGFHGP--------NCSQECRCHNGG------LCDRFTGQCRCAPGYTGDRCREECPV 308
C + F + + C C G LCD+ GQC C +G +C + C
Sbjct: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQN 678
Query: 309 GRFGQDCAETCDCAP-----------DARCFPANGACLCEHGFTGDRCTDRLCPDGFYGL 357
G + + C+P D C +G C C+ G RC C GF L
Sbjct: 679 GFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDH--CNFGFKFL 736
Query: 358 ------SCQAPCTCDREHSLS--CHPMNGECSCLPGWAGLHCNESCPQDTHG---PGCQE 406
C+ PC C+ S++ C+P +G+C C GL C ++C ++ +G C+
Sbjct: 737 RSFNDVGCE-PCQCNLHGSVNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNCKA 794
Query: 407 HCLC-----LHGGVCQATSGLCQCAPGYTGPHCASLCPPDTY----------GVNCSARC 451
C C L G VC A +G C C P G C + Y NC
Sbjct: 795 -CDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTG 853
Query: 452 SCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCN-----ASCQCAH-----EAV 501
+ ++ C+ G+C CK G C+ C P + + + C+C +
Sbjct: 854 TINGSLLCNKSTGQCPCKLGVTGLRCN-QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912
Query: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC-DCD-HSDG-----CDPVHGRCQC 554
C P +G C C P G C P G A+ C C H+ G C+ + G+C C
Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVC 972
Query: 555 Q-AGWMGARCHLSCPEGLWGVNCS----NTCTCKNGG----TCLPENGNCVCAPGFRGPS 605
Q A G RC C + +G + C C G TC G C C G
Sbjct: 973 QDASIAGQRCD-QCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSK 1031
Query: 606 CQRSCQP 612
C +C P
Sbjct: 1032 CD-ACVP 1037
Score = 117 bits (294), Expect = 4e-26
Identities = 129/468 (27%), Positives = 163/468 (34%), Gaps = 124/468 (26%)
Query: 146 KPCSCGN----NSS--CDPKSGVCSCPSGLQPPNCLQPCTPGYYG-----PACQFRCQCH 194
KPC C N S CD G C+C + C Q C G+Y P C C+
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGCSPCNCN 697
Query: 195 GA-------PCDPQTGACFCPAERTGPSCDVSCSQG---TSGFFCPSTHSCQ---NGGV- 240
+ C +G C C A G CD C+ G F CQ +G V
Sbjct: 698 TSGTVDGDITCHQNSGQCKCKANVIGLRCD-HCNFGFKFLRSFNDVGCEPCQCNLHGSVN 756
Query: 241 -FQTP-QGSCSCPPGWMGTICSLPCPEGFHG---PNCSQECRCHNGG-----LCDRFTGQ 290
F P G C C G C C E F+G NC + C C G +C+ TGQ
Sbjct: 757 KFCNPHSGQCECKKEAKGLQCD-TCRENFYGLDVTNC-KACDCDTAGSLPGTVCNAKTGQ 814
Query: 291 CRCAPGYTGDRCREECPVGRF-----------GQDCAETCDCAPDARCFPANGACLCEHG 339
C C P G +C +C G F +C +T C + G C C+ G
Sbjct: 815 CICKPNVEGRQC-NKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLG 873
Query: 340 FTGDRCTDRLCPDGFYGLS------CQAPCTCDREHSLS---CHPMNGECSCLPGWAGLH 390
TG RC C Y L+ CQ C CD +L C P++G+C C+P G
Sbjct: 874 VTGLRCNQ--CEPHRYNLTIDNFQHCQM-CECDSLGTLPGTICDPISGQCLCVPNRQGRR 930
Query: 391 CNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPG-YTGPHCASLCPPDTYGVNCSA 449
CN QC PG Y P A+ C P
Sbjct: 931 CN-------------------------------QCQPGFYISPGNATGCLP--------- 950
Query: 450 RCSCENAIA----CSPIDGECVCKEGWQRGNCSVPCPPGTWGFS--------CNASCQCA 497
CSC A C+ + G+CVC++ G C +GF CN A
Sbjct: 951 -CSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGA 1009
Query: 498 HEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGC 545
C TG C C G+ C P AS D ++ GC
Sbjct: 1010 LNETCHLVTGQCFCKQFVTGSKCDACVPS-------ASHLDVNNLLGC 1050
Score = 114 bits (284), Expect = 6e-25
Identities = 124/482 (25%), Positives = 168/482 (34%), Gaps = 115/482 (23%)
Query: 334 CLC-EHGFTGDRCTDRLCP----------DGFYGLSCQAPCTCDREHSLSCHPMNGECSC 382
CLC + FT DR P D Y +C+ PC C+ HS SCH N
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCK-PCQCN-SHSKSCH-YNISVDP 592
Query: 383 LP-----GWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL 437
P G G+ C++ C +T G C+ V S + C P
Sbjct: 593 FPFEHFRGGGGV-CDD-CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKP---------- 640
Query: 438 CPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPC-----------PPGTW 486
C DT G +I C I G+C CK C+ C P G
Sbjct: 641 CDCDTVGTR-------NGSILCDQIGGQCNCKRHVSGRQCN-QCQNGFYNLQELDPDGCS 692
Query: 487 GFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKG-----QFGEGCASRCDCDH 541
+CN S + C +G C C G C C G F + C C+
Sbjct: 693 PCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD-HCNFGFKFLRSFNDVGCEPCQCNL 751
Query: 542 SDG----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSN--TCTCKNGGT-----CLP 590
C+P G+C+C+ G +C +C E +G++ +N C C G+ C
Sbjct: 752 HGSVNKFCNPHSGQCECKKEAKGLQCD-TCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810
Query: 591 ENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQ 650
+ G C+C P G C KC +F N + CL
Sbjct: 811 KTGQCICKPNVEGRQCN---------------KCLEGNFYLRQNNSFLCL---------- 845
Query: 651 PCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCP----LGTFGANCSQ 706
PC NC +T + C+ G C C LG TG C + P L Q
Sbjct: 846 PC-------NCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQ 898
Query: 707 PCQCG-----PGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMP-----TTPVAYNSLG 756
C+C PG C P +G C+C P G C Q F + P P + ++ G
Sbjct: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN-QCQPGFYISPGNATGCLPCSCHTTG 957
Query: 757 AV 758
AV
Sbjct: 958 AV 959
Score = 73.6 bits (179), Expect = 9e-13
Identities = 84/314 (26%), Positives = 108/314 (34%), Gaps = 78/314 (24%)
Query: 494 CQC-AHEAVC--SPQTGACTCTPG--WHGAHCQLPCP---KGQFGEGC------ASRCDC 539
CQC H C + Q C C+ G HC P F +G C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 540 D-HSDGC------DPVH--------GRCQ-CQAGWMGARCHLSCPEGLW--------GVN 575
+ HS C DP G C C+ G C L C + + ++
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCEL-CKDYFFRQVGADPSAID 636
Query: 576 CSNTCTCKNGGT------CLPENGNCVCAPGFRGPSCQRSCQPGRYGKR------CVPCK 623
C C GT C G C C G C + CQ G Y + C PC
Sbjct: 637 VCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGCSPCN 695
Query: 624 CANHSF------CHPSNGTCYCLAGWTGPDCSQPCPPGH-----WGENCAQTCQCH-HGG 671
C CH ++G C C A G C C G + + + CQC+ HG
Sbjct: 696 CNTSGTVDGDITCHQNSGQCKCKANVIGLRCDH-CNFGFKFLRSFNDVGCEPCQCNLHGS 754
Query: 672 T---CHPQDGSCICPLGWTGHHCLEGCPLGTFG---ANCSQPCQCG-----PGEKCHPET 720
C+P G C C G C + C +G NC + C C PG C+ +T
Sbjct: 755 VNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNC-KACDCDTAGSLPGTVCNAKT 812
Query: 721 GACVCPPGHSGAPC 734
G C+C P G C
Sbjct: 813 GQCICKPNVEGRQC 826
Score = 73.6 bits (179), Expect = 9e-13
Identities = 68/263 (25%), Positives = 93/263 (35%), Gaps = 80/263 (30%)
Query: 119 QCQCVPGWRGDDCSSECAPGMWGPQCDK-----PCSCGNNSS------CDPKSGVCSCPS 167
QC C P G C+ +C G + + + PC+C + C+ +G C C
Sbjct: 814 QCICKPNVEGRQCN-KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKL 872
Query: 168 GLQPPNCLQPCTPGYYG------PACQFRCQCH------GAPCDPQTGACFCPAERTGPS 215
G+ C Q C P Y CQ C+C G CDP +G C C R G
Sbjct: 873 GVTGLRCNQ-CEPHRYNLTIDNFQHCQM-CECDSLGTLPGTICDPISGQCLCVPNRQGRR 930
Query: 216 CDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQE 275
C + CQ G + +P + C P
Sbjct: 931 C----------------NQCQ-PGFYISPGNATGCLP----------------------- 950
Query: 276 CRCHNGG----LCDRFTGQCRCA-PGYTGDRCREECPVGRFGQD----CAETCDC----A 322
C CH G +C+ TGQC C G RC ++C FG D + C+C A
Sbjct: 951 CSCHTTGAVNHICNSLTGQCVCQDASIAGQRC-DQCKDHYFGFDPQTGRCQPCNCHLSGA 1009
Query: 323 PDARCFPANGACLCEHGFTGDRC 345
+ C G C C+ TG +C
Sbjct: 1010 LNETCHLVTGQCFCKQFVTGSKC 1032
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.140 0.516
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,169,106
Number of Sequences: 37866
Number of extensions: 4412707
Number of successful extensions: 33921
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 947
Number of HSP's that attempted gapping in prelim test: 14221
Number of HSP's gapped (non-prelim): 7689
length of query: 1037
length of database: 18,247,518
effective HSP length: 112
effective length of query: 925
effective length of database: 14,006,526
effective search space: 12956036550
effective search space used: 12956036550
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.