Search of human proteins with 122937233

Search of human proteins with 122937233

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937233 discs, large (Drosophila) homolog-associated
protein 3 [Homo sapiens]
         (979 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937233 discs, large (Drosophila) homolog-associated protei...  2031   0.0  
gi|38202224 discs large-associated protein 2 [Homo sapiens]           811   0.0  
gi|19923274 discs large homolog-associated protein 1 isoform alp...   629   e-180
gi|34335253 disks large-associated protein 4 isoform a [Homo sap...   500   e-141
gi|51339031 discs large homolog-associated protein 1 isoform bet...   475   e-134
gi|34335251 disks large-associated protein 4 isoform b [Homo sap...   311   2e-84
gi|109891938 disks large-associated protein 4 isoform c [Homo sa...   261   3e-69
gi|226371669 discs large homolog 7 isoform b [Homo sapiens]            77   1e-13
gi|226371667 discs large homolog 7 isoform a [Homo sapiens]            77   1e-13
gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    55   2e-07
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       54   7e-07
gi|20070107 orthodenticle homeobox 1 [Homo sapiens]                    54   9e-07
gi|4507955 YY1 transcription factor [Homo sapiens]                     52   3e-06
gi|55750053 atrophin-1 [Homo sapiens]                                  51   6e-06
gi|55750041 atrophin-1 [Homo sapiens]                                  51   6e-06
gi|40288197 GATA binding protein 6 [Homo sapiens]                      50   8e-06
gi|7710129 LIM domain only 6 [Homo sapiens]                            50   1e-05
gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapi...    49   2e-05
gi|61966923 forkhead box B2 [Homo sapiens]                             49   2e-05
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula...    49   2e-05
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula...    49   2e-05
gi|57864582 hornerin [Homo sapiens]                                    49   3e-05
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    49   3e-05
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    49   3e-05
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    49   3e-05
gi|148762982 hypothetical protein LOC387640 [Homo sapiens]             48   4e-05
gi|84105335 mesenchyme homeobox 2 [Homo sapiens]                       48   5e-05
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       48   5e-05
gi|134288896 hypothetical protein LOC143684 [Homo sapiens]             48   5e-05
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof...    48   5e-05

>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
           [Homo sapiens]
          Length = 979

 Score = 2031 bits (5261), Expect = 0.0
 Identities = 979/979 (100%), Positives = 979/979 (100%)

Query: 1   MRGYHGDRGSHPRPARFADQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGHISPE 60
           MRGYHGDRGSHPRPARFADQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGHISPE
Sbjct: 1   MRGYHGDRGSHPRPARFADQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGHISPE 60

Query: 61  GPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLPPT 120
           GPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLPPT
Sbjct: 61  GPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLPPT 120

Query: 121 LLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKL 180
           LLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKL
Sbjct: 121 LLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKL 180

Query: 181 FAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGK 240
           FAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGK
Sbjct: 181 FAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGK 240

Query: 241 RSKSKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLS 300
           RSKSKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLS
Sbjct: 241 RSKSKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLS 300

Query: 301 FKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPGKGLLGPETKA 360
           FKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPGKGLLGPETKA
Sbjct: 301 FKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPGKGLLGPETKA 360

Query: 361 KARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESGDSDGSPKTSPKAV 420
           KARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESGDSDGSPKTSPKAV
Sbjct: 361 KARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESGDSDGSPKTSPKAV 420

Query: 421 ARRFTTRRSSSVDQARINCCVPPRIHPRSSIPGYSRSLTTGQLSDELNQQLEAVCGSVFG 480
           ARRFTTRRSSSVDQARINCCVPPRIHPRSSIPGYSRSLTTGQLSDELNQQLEAVCGSVFG
Sbjct: 421 ARRFTTRRSSSVDQARINCCVPPRIHPRSSIPGYSRSLTTGQLSDELNQQLEAVCGSVFG 480

Query: 481 ELESQAVDALDLPGCFRMRSHSYLRAIQAGCSQDDDCLPLLATPAAVSGRPGSSFNFRKA 540
           ELESQAVDALDLPGCFRMRSHSYLRAIQAGCSQDDDCLPLLATPAAVSGRPGSSFNFRKA
Sbjct: 481 ELESQAVDALDLPGCFRMRSHSYLRAIQAGCSQDDDCLPLLATPAAVSGRPGSSFNFRKA 540

Query: 541 PPPIPPGSQAPPRISITAQSSTDSAHESFTAAEGPARRCSSADGLDGPAMGARTLELAPV 600
           PPPIPPGSQAPPRISITAQSSTDSAHESFTAAEGPARRCSSADGLDGPAMGARTLELAPV
Sbjct: 541 PPPIPPGSQAPPRISITAQSSTDSAHESFTAAEGPARRCSSADGLDGPAMGARTLELAPV 600

Query: 601 PPRASPKPPTLIIKTIPGREELRSLARQRKWRPSIGVQVETISDSDTENRSRREFHSIGV 660
           PPRASPKPPTLIIKTIPGREELRSLARQRKWRPSIGVQVETISDSDTENRSRREFHSIGV
Sbjct: 601 PPRASPKPPTLIIKTIPGREELRSLARQRKWRPSIGVQVETISDSDTENRSRREFHSIGV 660

Query: 661 QVEEDKRRARFKRSNSVTAGVQADLELEGLAGLATVATEDKALQFGRSFQRHASEPQPGP 720
           QVEEDKRRARFKRSNSVTAGVQADLELEGLAGLATVATEDKALQFGRSFQRHASEPQPGP
Sbjct: 661 QVEEDKRRARFKRSNSVTAGVQADLELEGLAGLATVATEDKALQFGRSFQRHASEPQPGP 720

Query: 721 RAPTYSVFRTVHTQGQWAYREGYPLPYEPPATDGSPGPAPAPTPGPGAGRRDSWIERGSR 780
           RAPTYSVFRTVHTQGQWAYREGYPLPYEPPATDGSPGPAPAPTPGPGAGRRDSWIERGSR
Sbjct: 721 RAPTYSVFRTVHTQGQWAYREGYPLPYEPPATDGSPGPAPAPTPGPGAGRRDSWIERGSR 780

Query: 781 SLPDSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGST 840
           SLPDSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGST
Sbjct: 781 SLPDSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGST 840

Query: 841 QLLLSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANS 900
           QLLLSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANS
Sbjct: 841 QLLLSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANS 900

Query: 901 WKLLEPKEEKKVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSS 960
           WKLLEPKEEKKVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSS
Sbjct: 901 WKLLEPKEEKKVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSS 960

Query: 961 ATESADSIEIYIPEAQTRL 979
           ATESADSIEIYIPEAQTRL
Sbjct: 961 ATESADSIEIYIPEAQTRL 979


>gi|38202224 discs large-associated protein 2 [Homo sapiens]
          Length = 975

 Score =  811 bits (2096), Expect = 0.0
 Identities = 490/1029 (47%), Positives = 618/1029 (60%), Gaps = 147/1029 (14%)

Query: 19  DQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEGPSVGPEGGPA 78
           D +H+  GP AR PYLL   ++       C+PR+ +       P+ L +  S        
Sbjct: 26  DCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSSVHSECVMMPVVLGDHVS-------- 77

Query: 79  GAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHT 138
                  SSTFPRM+     +DT +DC     G    R+P  LLDQFEKQLP+ +DGFHT
Sbjct: 78  -------SSTFPRMHYSSH-YDTRDDCAVAHAGAKINRIPANLLDQFEKQLPLHRDGFHT 129

Query: 139 LPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGP 198
           L YQR            T  A E RSESP RIRHLVHSVQKLF KSHSLE   K + NG 
Sbjct: 130 LQYQR------------TSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNANGT 177

Query: 199 KAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKST 258
           KA+GR                          HHH H ++H KRSKSK+RK +G+ +   +
Sbjct: 178 KADGRADD-----------------------HHHAHHAKHSKRSKSKERKPEGKPRPGMS 214

Query: 259 GWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDG---SYRDLSFKGRSGGSEGRCLAC 315
            WWSSDDNLDSDS +           GP     PD     + DLS K     ++ +C AC
Sbjct: 215 SWWSSDDNLDSDSTYRTPSVLNRHHLGPVAHCYPDALQSPFGDLSLKTSKSNNDVKCSAC 274

Query: 316 TGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPG--KGLLGPETKAKARTYHYLQVPQD 373
            G++++ D + +KRS+W T+ VSQ ++ Y  +     K LL  + K   R  HYLQVPQD
Sbjct: 275 EGLALTPDAKYLKRSSWSTLTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQD 334

Query: 374 DWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESGDSDGSPKTSPKAVA-----------R 422
           +WGGYPTGGKD EIPCRRMRSGSYIKAMGDEESG+SD SPKTSPK+             R
Sbjct: 335 EWGGYPTGGKDEEIPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLLKSIGQR 394

Query: 423 RFTTRRSSSVDQARINCCVPPRIHP---------RSSIPGYSRSLTT-------GQLSD- 465
                ++ +  QA  +  V   + P         RS    Y R+++T        Q+S+ 
Sbjct: 395 PLGEHQTQTYLQAASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEA 454

Query: 466 ELNQQLEAVCGSVFGELESQAVDALDLPGCFRMRSHSYLRAIQAGCSQDDDCLPLLATPA 525
           E+N Q E+VC SVF E+ESQA+DALDLPGCFR RSHSYLRAIQAG SQDD+C+P++ TP+
Sbjct: 455 EINGQFESVCESVFSEVESQAMDALDLPGCFRTRSHSYLRAIQAGYSQDDECIPMM-TPS 513

Query: 526 AVSGRPGSSF-----NFRKAPPPIPPGSQAPPRISITAQSSTDSAHESFTAAEGPARRCS 580
            ++    S+      N++K PPP+PP + + P IS+TAQSST+S  +++   +  A+R S
Sbjct: 514 DITSTIRSTAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQ--DSRAQRMS 571

Query: 581 -----------SADGLDGPAMGARTLELAPVPPRASPKPPTLIIKTIPGREELRSLARQR 629
                      S D LD        LE A    R  P+  +  ++T      +       
Sbjct: 572 PWPQDSRGLYNSTDSLDSNKAMNLALETAAAQ-RHLPESQSSSVRTSDKAILVSKAEELL 630

Query: 630 KWR-PSIGVQ--------------VETISDSDTENRSRREFHSIGVQVEEDKRRARFKRS 674
           K R  SIG+Q              VET +DSDTE+R  RE+HS+GVQVE++KR  RFKRS
Sbjct: 631 KSRCSSIGIQDSEFPEHQPYPRSDVETATDSDTESRGLREYHSVGVQVEDEKRHGRFKRS 690

Query: 675 NSVTAGVQADLELEGLAGLATVATEDKALQFGRSFQRHASEPQPGPRAPT-YSVFRTVHT 733
           NSVTA VQADLELEG  G  T  TEDK LQFG SFQRH+      P  PT YS  RTV T
Sbjct: 691 NSVTAAVQADLELEGFPGHIT--TEDKGLQFGSSFQRHSE-----PSTPTQYSAVRTVRT 743

Query: 734 QGQWAYREGYPLPYEPPATDGSPGPAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPR 793
           QG ++YRE Y         D S  P P P           W+E    ++ ++GR SPC R
Sbjct: 744 QGLFSYREDYRTQ-----VDTSTLPPPDP-----------WLEPAIDTV-ETGRMSPCRR 786

Query: 794 DGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFR 853
           DG WF+K+L AE +++E WC++MEREAE+ +L EEIL KIRSAVGS QLL+SQK QQF+ 
Sbjct: 787 DGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYW 846

Query: 854 LCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKLLEP---KEEK 910
           LCQQ+MDP+A P PT QDLAG+WD+LQLSIEDV++KF ELQ+L+ N WK++E    KEE+
Sbjct: 847 LCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESPERKEER 906

Query: 911 KVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEI 970
           KVPPPIPKKP +G+    +E+SLD  DRQRQEAR+RL+AAKRAASFR +SA+E ADSIEI
Sbjct: 907 KVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSASERADSIEI 966

Query: 971 YIPEAQTRL 979
           YIPEAQTRL
Sbjct: 967 YIPEAQTRL 975


>gi|19923274 discs large homolog-associated protein 1 isoform alpha
           [Homo sapiens]
          Length = 977

 Score =  629 bits (1622), Expect = e-180
 Identities = 433/1073 (40%), Positives = 571/1073 (53%), Gaps = 190/1073 (17%)

Query: 1   MRGYHGDRGSHPR----PARFADQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGH 56
           M+G  G R  H       A  +   H D     R PYLL   E    +  +   R     
Sbjct: 1   MKGLSGSRSHHHGVTCDSACDSLSHHSD-----RKPYLLSPVEHHPADHPYYTQRNSF-- 53

Query: 57  ISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRM-YPGQGPFDTCEDCVGHPQ--GKG 113
                     +   VGP   P        SSTFPR  Y  Q      ++C   P+     
Sbjct: 54  ----------QAECVGPFSDPLA------SSTFPRRHYTSQQELK--DECALVPRTLATK 95

Query: 114 APRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHL 173
           A R+P  LLDQFE+QLP+ +DG+HTL Y+R              TA E RS+SP RIRHL
Sbjct: 96  ANRIPANLLDQFERQLPLSRDGYHTLQYKR--------------TAVEHRSDSPGRIRHL 141

Query: 174 VHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHH 233
           VHSVQKLF KSHSLE P K   NG KA                                 
Sbjct: 142 VHSVQKLFTKSHSLEGPSKGSVNGGKASPDEAQA-------------------------- 175

Query: 234 HQSRHGKRSKSKDRKGDGRHQ-AKSTGWWSSDDNLDSD-------SGFLAGGRPPGEPGG 285
             +R+GKRSKSK+R+ + + + + S GWWSSDDNLD D       SG +  GR P     
Sbjct: 176 --ARYGKRSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVMTMGRCPDRSAS 233

Query: 286 PFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWH-TMMVSQGRDGY 344
            + LE  + +  + + K     ++ +C  C  + +SLD   +K+SAW  T+ VS+ R+ Y
Sbjct: 234 QYFLEAYN-TISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSSTLTVSRAREVY 292

Query: 345 PGAGPG--KGLLGPETKAKARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMG 402
             A     + ++  E+  + R+  YLQVPQD+W GY   GKD EIPCRRMRSGSYIKAMG
Sbjct: 293 QKASVNMDQAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMG 352

Query: 403 DEESGDSDGSPKTSPKAVARR-------------FTTRRSSS----------------VD 433
           DE+SGDSD SPK SPK  ARR              TT + S+                V 
Sbjct: 353 DEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVS 412

Query: 434 QARIN----------CCVPPRIHPRSSIPGYSRSLTT-GQLSD-ELNQQLEAVCGSVFGE 481
           +  IN              P+   R+    Y R+++T  Q+S+ E+N Q E+VC SVF E
Sbjct: 413 EVSINRSLDSLDPAGLLTSPKFRSRNE--SYMRAMSTISQVSEMEVNGQFESVCESVFSE 470

Query: 482 LESQAVDALDLP--GCFRMRSHSYLRAIQAGCSQDDDCLPLLA--------TPAAVSGRP 531
           LESQAV+ALDLP  GCFRMRSHSY+RAI+ GCSQDD+C+ L +        T   +    
Sbjct: 471 LESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSST 530

Query: 532 GSSF--NFRKAPPPIPPGSQAPPRISITAQSSTDSAHESFTAAEGPARRCSSADGLDGP- 588
            SS    ++K PPP+PP +   P ISITAQSST+SA +++   +G      S  GL    
Sbjct: 531 VSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNST 590

Query: 589 ----AMGARTLEL----APVPPRASPK--------PPTLIIKTIPGREELRSLARQRKWR 632
               +M A T  +    A +   AS            T  I T+   +  +   ++ +  
Sbjct: 591 ESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCL 650

Query: 633 PSIGVQVETISDSDT--ENRSRREFHSIGVQVEEDKRRARFKRSNSVTAGVQADLELEGL 690
            SIG+QV+   + D   EN++  +F S+GVQVEE+K   RF RSNSVT  VQADL+    
Sbjct: 651 -SIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDN 709

Query: 691 AGLATVATEDKALQ--FGRSFQRHASEPQPGPRAPTYSVFRTVHTQGQWAYREGYPLPYE 748
              +  + ED +      R F R AS               TV  QG   +        +
Sbjct: 710 LENSLESIEDNSCPGPMARQFSRDASTS-------------TVSIQGSGNHYHACAAD-D 755

Query: 749 PPATDGSPGPAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEK 808
              TD  P   P P P         WI+  +    ++ + S C RDG WF+K+L+AE ++
Sbjct: 756 DFDTDFDPSILPPPDP---------WIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDR 806

Query: 809 LEHWCQQMEREAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPT 868
           +E WCQQMERE  +  LPE+IL KIR+AVGS QLL++QK  QF  LC+++++P A P PT
Sbjct: 807 MEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPT 866

Query: 869 FQDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKLLEP--KEEKKVPPPIPKKPLRGRGV 926
            QDLAGFWD+LQLSIE++++KF EL QLKAN+WK ++P  K+E++ PPP+PKKP +G   
Sbjct: 867 SQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPKKPAKGPAP 926

Query: 927 PVKERSLDSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL 979
            ++ERSL+S   QRQEARKRL+AAKRAAS R +SATESA+SIEIYIPEAQTRL
Sbjct: 927 LIRERSLES--SQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977


>gi|34335253 disks large-associated protein 4 isoform a [Homo
           sapiens]
          Length = 989

 Score =  500 bits (1288), Expect = e-141
 Identities = 380/1074 (35%), Positives = 500/1074 (46%), Gaps = 237/1074 (22%)

Query: 30  RAPYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEGPSVGPEGG--PAGAGVGGGSS 87
           R PYLL   EAF+ E RF                    G +  P  G  P    +   SS
Sbjct: 29  RNPYLLSPTEAFAREARF-------------------PGQNTLPGDGLFPLNNQLPPPSS 69

Query: 88  TFPRMY-------PGQGPFDTCEDCVGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLP 140
           TFPR++       P + PF +      H Q     RLP  LLDQFEKQLP+ +DGF TL 
Sbjct: 70  TFPRIHYNSHFEVPEESPFPS------HAQATKINRLPANLLDQFEKQLPIHRDGFSTLQ 123

Query: 141 YQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKA 200
           + RG A A              R ESP RIRHLVHSVQ+LF                P  
Sbjct: 124 FPRGEAKA--------------RGESPGRIRHLVHSVQRLFFTK------------APSL 157

Query: 201 EGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKS--- 257
           EG  G  G +  G   GG                +   G+R+KSK+R   G  + +S   
Sbjct: 158 EGTAGKVGGN--GSKKGGM---------------EDGKGRRAKSKERAKAGEPKRRSRSN 200

Query: 258 -TGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCL--- 313
            +GWWSSDDNLD ++G     R  G   G   L       +   F        G  L   
Sbjct: 201 ISGWWSSDDNLDGEAGAF---RSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKTT 257

Query: 314 ------------------ACTGMSMSLDGQSVKRSAWHTMMVSQGRD--GYPGAGPGKGL 353
                              C  + +  D   VKR +W T+ +S   +      A   K L
Sbjct: 258 KNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSL 317

Query: 354 LGPETKAKARTYHYLQVPQDDWGGYPT---------GGKDGEIPCRRMRSGSYIKAMGDE 404
           L  ++  +   YHYLQVP    G + T            +G IPCRRMRSGSYIKAMGDE
Sbjct: 318 LKSKSCHQGLAYHYLQVPGGG-GEWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDE 376

Query: 405 ESGDSDGSPKTSPKAVARRFTTRRSSSV-------------------------------- 432
           +S +S GSPK SPK  ARR +  R++                                  
Sbjct: 377 DSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEED 436

Query: 433 -----DQARINCCVPPRIHPRSSIP---GYSRSLTTGQLSDELNQQLEAVCGSVFGELES 484
                D    + C+       S IP   G+ + +   +LSD    Q EA C S   E ES
Sbjct: 437 YTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSD----QYEAACESACSEAES 492

Query: 485 QAVDALDLP--GCFRMRSHSYLRAIQAGCSQDDDCLPLLA-TPAAVSGR-------PGSS 534
            A + LDLP    FR RSHSYLRAIQAGCSQ++D + L + +P   +G        P SS
Sbjct: 493 TAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSS 552

Query: 535 --FNFRKAPPPIPPGSQAPPRISITAQSSTDSAHESF----------TAAEGPARRCSSA 582
               ++K PPP+PP + + P IS+T QSST+SA +++          T+  G +    S 
Sbjct: 553 CLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSL 612

Query: 583 DGLDGPAMGARTLELAPVPPRASPKPPTLIIKTIPGREELRSLARQRKWRPSIGVQVETI 642
           D    P    R   +AP P    P P    +K+  G                      T 
Sbjct: 613 DSSTRPPSVTRG-GVAPAPEAPEPPPKHAALKSEQG--------------------TLTS 651

Query: 643 SDSDTENRSRREFHSIGVQVEEDKRRARFKRSNSVTA-GVQADLELEGLAGLATVA---- 697
           S+S  E   +R+  SIG+Q    +  +     N   A  V A      +   +  +    
Sbjct: 652 SESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDT 711

Query: 698 ---TEDKALQFGRSFQRHASEPQPGPRAPTYSVF-----RTVHTQGQWAYREGYPLPYEP 749
              T+D      +S +R   +  P P + +         +    +   +Y +        
Sbjct: 712 DSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN-----SD 766

Query: 750 PATDGSPGPAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEKL 809
           PA + S  P P P           W+E  S S  +  +   C RDG WF+K+L+AE E+L
Sbjct: 767 PALEASSLPPPDP-----------WLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERL 815

Query: 810 EHWCQQMEREAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPTF 869
           E WC QM++E ++  L EE+L K+ SAVGS QLL+SQK QQF  LC+Q+++P A P PT 
Sbjct: 816 EGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTA 875

Query: 870 QDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKLLEP----KEEKKVPPPIPKKPLRGRG 925
           QDLAGFWDLLQLSIED+++KF EL  LKANSW+L+E     KEEKK PPP+PKKP + + 
Sbjct: 876 QDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKP 935

Query: 926 VPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL 979
              ++++ D+ D+QRQEARKRLLAAKRAAS R +SATESADSIEIY+PEAQTRL
Sbjct: 936 AVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 989


>gi|51339031 discs large homolog-associated protein 1 isoform beta
           [Homo sapiens]
          Length = 675

 Score =  475 bits (1223), Expect = e-134
 Identities = 304/687 (44%), Positives = 398/687 (57%), Gaps = 104/687 (15%)

Query: 369 QVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESGDSDGSPKTSPKAVARR----- 423
           +VPQD+W GY   GKD EIPCRRMRSGSYIKAMGDE+SGDSD SPK SPK  ARR     
Sbjct: 17  KVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLK 76

Query: 424 --------FTTRRSSS----------------VDQARIN----------CCVPPRIHPRS 449
                    TT + S+                V +  IN              P+   R+
Sbjct: 77  ATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRN 136

Query: 450 SIPGYSRSLTT-GQLSD-ELNQQLEAVCGSVFGELESQAVDALDLP--GCFRMRSHSYLR 505
               Y R+++T  Q+S+ E+N Q E+VC SVF ELESQAV+ALDLP  GCFRMRSHSY+R
Sbjct: 137 E--SYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVR 194

Query: 506 AIQAGCSQDDDCLPLLA--------TPAAVSGRPGSSF--NFRKAPPPIPPGSQAPPRIS 555
           AI+ GCSQDD+C+ L +        T   +     SS    ++K PPP+PP +   P IS
Sbjct: 195 AIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFIS 254

Query: 556 ITAQSSTDSAHESFTAAEGPARRCSSADGLDGP-----AMGARTLEL----APVPPRASP 606
           ITAQSST+SA +++   +G      S  GL        +M A T  +    A +   AS 
Sbjct: 255 ITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQ 314

Query: 607 K--------PPTLIIKTIPGREELRSLARQRKWRPSIGVQVETISDSDT--ENRSRREFH 656
                      T  I T+   +  +   ++ +   SIG+QV+   + D   EN++  +F 
Sbjct: 315 HMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCL-SIGIQVDDAEEPDKTGENKAPSKFQ 373

Query: 657 SIGVQVEEDKRRARFKRSNSVTAGVQADLELEGLAGLATVATEDKALQ--FGRSFQRHAS 714
           S+GVQVEE+K   RF RSNSVT  VQADL+       +  + ED +      R F R AS
Sbjct: 374 SVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDAS 433

Query: 715 EPQPGPRAPTYSVFRTVHTQGQWAYREGYPLPYEPPATDGSPGPAPAPTPGPGAGRRDSW 774
                          TV  QG   +        +   TD  P   P P P         W
Sbjct: 434 TS-------------TVSIQGSGNHYHACAAD-DDFDTDFDPSILPPPDP---------W 470

Query: 775 IERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIR 834
           I+  +    ++ + S C RDG WF+K+L+AE +++E WCQQMERE  +  LPE+IL KIR
Sbjct: 471 IDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIR 530

Query: 835 SAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQ 894
           +AVGS QLL++QK  QF  LC+++++P A P PT QDLAGFWD+LQLSIE++++KF EL 
Sbjct: 531 TAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELH 590

Query: 895 QLKANSWKLLEP--KEEKKVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKR 952
           QLKAN+WK ++P  K+E++ PPP+PKKP +G    ++ERSL+S   QRQEARKRL+AAKR
Sbjct: 591 QLKANNWKQMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLES--SQRQEARKRLMAAKR 648

Query: 953 AASFRHSSATESADSIEIYIPEAQTRL 979
           AAS R +SATESA+SIEIYIPEAQTRL
Sbjct: 649 AASVRQNSATESAESIEIYIPEAQTRL 675


>gi|34335251 disks large-associated protein 4 isoform b [Homo
           sapiens]
          Length = 453

 Score =  311 bits (796), Expect = 2e-84
 Identities = 193/466 (41%), Positives = 261/466 (56%), Gaps = 53/466 (11%)

Query: 537 FRKAPPPIPPGSQAPPRISITAQSSTDSAHESF----------TAAEGPARRCSSADGLD 586
           ++K PPP+PP + + P IS+T QSST+SA +++          T+  G +    S D   
Sbjct: 18  YKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSST 77

Query: 587 GPAMGARTLELAPVPPRASPKPPTLIIKTIPGR---EELRSLARQRKWRPSIGVQVETIS 643
            P    R   +AP P    P P    +K+  G     E    A  ++   SIG+QV+ I 
Sbjct: 78  RPPSVTRG-GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQ 136

Query: 644 DSDTENRS-RREFHSIGVQVEEDKRRARFKRSNSVTAGVQADLELEGLAGLATVATEDKA 702
               E  S   +F SIGVQVE+D R +    S S      +D             T+D  
Sbjct: 137 PVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSD-------------TQDAN 183

Query: 703 LQFGRSFQRHASEPQPGPRAPTYSVF-----RTVHTQGQWAYREGYPLPYEPPATDGSPG 757
               +S +R   +  P P + +         +    +   +Y +        PA + S  
Sbjct: 184 DSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN-----SDPALEASSL 238

Query: 758 PAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQME 817
           P P P           W+E  S S  +  +   C RDG WF+K+L+AE E+LE WC QM+
Sbjct: 239 PPPDP-----------WLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMD 287

Query: 818 REAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWD 877
           +E ++  L EE+L K+ SAVGS QLL+SQK QQF  LC+Q+++P A P PT QDLAGFWD
Sbjct: 288 KETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWD 347

Query: 878 LLQLSIEDVTLKFLELQQLKANSWKLLEP----KEEKKVPPPIPKKPLRGRGVPVKERSL 933
           LLQLSIED+++KF EL  LKANSW+L+E     KEEKK PPP+PKKP + +    ++++ 
Sbjct: 348 LLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKAS 407

Query: 934 DSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL 979
           D+ D+QRQEARKRLLAAKRAAS R +SATESADSIEIY+PEAQTRL
Sbjct: 408 DASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453


>gi|109891938 disks large-associated protein 4 isoform c [Homo
           sapiens]
          Length = 285

 Score =  261 bits (666), Expect = 3e-69
 Identities = 134/234 (57%), Positives = 169/234 (72%), Gaps = 15/234 (6%)

Query: 750 PATDGSPGPAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEKL 809
           PA + S  P P P           W+E  S S  +  +   C RDG WF+K+L+AE E+L
Sbjct: 63  PALEASSLPPPDP-----------WLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERL 111

Query: 810 EHWCQQMEREAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPTF 869
           E WC QM++E ++  L EE+L K+ SAVGS QLL+SQK QQF  LC+Q+++P A P PT 
Sbjct: 112 EGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTA 171

Query: 870 QDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKLLEP----KEEKKVPPPIPKKPLRGRG 925
           QDLAGFWDLLQLSIED+++KF EL  LKANSW+L+E     KEEKK PPP+PKKP + + 
Sbjct: 172 QDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKP 231

Query: 926 VPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL 979
              ++++ D+ D+QRQEARKRLLAAKRAAS R +SATESADSIEIY+PEAQTRL
Sbjct: 232 AVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 285


>gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
          Length = 842

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 56/187 (29%), Positives = 87/187 (46%), Gaps = 8/187 (4%)

Query: 784 DSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGSTQLL 843
           + GR +       +F  +L++E EKL   C + +R+ E  ++P++  + IR+AVG T+LL
Sbjct: 419 NEGRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLE-LDIPDDAKDLIRTAVGQTRLL 477

Query: 844 LSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKL 903
           + ++ +QF  L             T  DL GFWD++   IEDV  KF  L +L+ + W++
Sbjct: 478 MKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQV 537

Query: 904 LEPKEEKKVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKRA--ASFRHSSA 961
                         KK + G     K+      D  R  AR RL A K A     R    
Sbjct: 538 NNNMNHNMNKNVFRKKVVSGIASKPKQD-----DAGRIAARNRLAAIKNAMRERIRQEEC 592

Query: 962 TESADSI 968
            E+A S+
Sbjct: 593 AETAVSV 599


>gi|226371667 discs large homolog 7 isoform a [Homo sapiens]
          Length = 846

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 56/187 (29%), Positives = 87/187 (46%), Gaps = 8/187 (4%)

Query: 784 DSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGSTQLL 843
           + GR +       +F  +L++E EKL   C + +R+ E  ++P++  + IR+AVG T+LL
Sbjct: 419 NEGRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLE-LDIPDDAKDLIRTAVGQTRLL 477

Query: 844 LSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKL 903
           + ++ +QF  L             T  DL GFWD++   IEDV  KF  L +L+ + W++
Sbjct: 478 MKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQV 537

Query: 904 LEPKEEKKVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKRA--ASFRHSSA 961
                         KK + G     K+      D  R  AR RL A K A     R    
Sbjct: 538 NNNMNHNMNKNVFRKKVVSGIASKPKQD-----DAGRIAARNRLAAIKNAMRERIRQEEC 592

Query: 962 TESADSI 968
            E+A S+
Sbjct: 593 AETAVSV 599


>gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           A [Homo sapiens]
          Length = 353

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 55/200 (27%), Positives = 63/200 (31%), Gaps = 57/200 (28%)

Query: 43  TEPRFCAPRAGLGHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTC 102
           + P FCAP  G G                    G  GAG GGGSS   +     GP    
Sbjct: 64  SSPSFCAPSPGTG--------------------GGGGAGGGGGSS---QAGGAPGPPSGG 100

Query: 103 EDCVGHPQGKGAPRLPPTLLDQFEK---QLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTA 159
              VG   GK      P L D +     Q  +  +  +  P     A  G G        
Sbjct: 101 PGAVGGTSGK------PALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSG-------- 146

Query: 160 PEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGP 219
                       H  H         H   A     + GP   G GG   D   G   G  
Sbjct: 147 -----------HHGAHH-----GAHHPAAAAAYEAFRGPGFAG-GGGADDMGAGHHHGAH 189

Query: 220 HTSHHHHHHHHHHHHQSRHG 239
           H +HHHH  HHHHHH   HG
Sbjct: 190 HAAHHHHAAHHHHHHHHHHG 209


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 67/248 (27%), Positives = 85/248 (34%), Gaps = 41/248 (16%)

Query: 28  AARAPYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSS 87
           AA A     + EA S         AG     P+ P    +GP V  +GG     +  G++
Sbjct: 106 AAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDV--KGGAGRDDLHAGTA 163

Query: 88  TFPRMYPGQGPFDTCEDCVGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAG 147
              R  P  GP        GHP G GA                               A 
Sbjct: 164 LHHRGPPHLGP-PPPPPHQGHPGGWGAAAAAAAAA--------------------AAAAA 202

Query: 148 AGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSG 207
           A   P+   G  P P+S        L++S    F  +  L AP      GP   G G  G
Sbjct: 203 AAHLPSMAGGQQPPPQS--------LLYSQPGGFTVNGMLSAPP-----GPGGGGGGAGG 249

Query: 208 GDS---YPGPGSGG-PHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSS 263
           G     +PG   G  P  + HHHHHHHH H    H   ++     G G   A   G  S 
Sbjct: 250 GAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGGA-GPGLNSH 308

Query: 264 DDNLDSDS 271
           D + D D+
Sbjct: 309 DPHSDEDT 316


>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
          Length = 354

 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 52/175 (29%), Positives = 66/175 (37%), Gaps = 62/175 (35%)

Query: 145 PAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRG 204
           PA   PG AP + + PEP + +PS    +  SV    A + +         + P + G+G
Sbjct: 179 PASISPGSAPASVSVPEPLA-APSNTSCMQRSVAAGAATAAA---------SYPMSYGQG 228

Query: 205 GSGGDSYPGPGS---GG--------PHTSHHH---------------------------- 225
           GS G  YP P S   GG        P  SHHH                            
Sbjct: 229 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQ 288

Query: 226 ----HHHHHHHHHQSRHG-----KRSKSKDRKGDGRHQAKSTGW---WSSDDNLD 268
               HHHHHHHHHQ   G       +   D K  G   A S+ W   ++S D LD
Sbjct: 289 SSGHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGA-AAASSAWKLNFNSPDCLD 342


>gi|4507955 YY1 transcription factor [Homo sapiens]
          Length = 414

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 3/70 (4%)

Query: 164 SESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSH 223
           SE P+ I  L H ++       ++E     +      +   G GGD   G G G  H  H
Sbjct: 14  SEMPAEIVEL-HEIEVETIPVETIETTVVGEEEEEDDDDEDGGGGDH--GGGGGHGHAGH 70

Query: 224 HHHHHHHHHH 233
           HHHHHHHHHH
Sbjct: 71  HHHHHHHHHH 80


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 63/262 (24%), Positives = 91/262 (34%), Gaps = 55/262 (20%)

Query: 50  PRAGLGHISPEGPLSLSE-GPSVGPEGGPAGAGVGGGS-------STFPRMYPGQGP--- 98
           P  G  H  P  P+S+S  G S  P   P    VGGG+       + FP + P   P   
Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA 306

Query: 99  FDTCEDCVGHPQGKGAPRLP-----PTLLDQFEKQLPVQQDGFHTL---PYQRGPAGAGP 150
                +    P G GA  LP     P  + Q    LP   +   TL   P+   PA +  
Sbjct: 307 LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS- 365

Query: 151 GPAP----------GTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNG--- 197
            PAP           +  A    S S S       + Q L +  HS   P     +    
Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP 425

Query: 198 -------------------PKAEGRGGSGGDSYPGP---GSGGPHTSHHHHHHHHHHHHQ 235
                              P   GR  +  +++PGP    +G   T+H     HHHHH Q
Sbjct: 426 KYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485

Query: 236 SRHGKRSKSKDRKGDGRHQAKS 257
            +  ++ + + ++   +H   S
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNS 507



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 48/194 (24%), Positives = 60/194 (30%), Gaps = 40/194 (20%)

Query: 10  SHPRPARFADQQHMDVGPAA-RAPYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEG 68
           S PR    + + H  V P    AP    +   F   P    P   L    P G   +  G
Sbjct: 174 STPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL---YPGGTGGVLSG 230

Query: 69  PSVGPEGGPAGAGVGG-------------------GSSTFPRMYP-----GQGPFDTCED 104
           P +GP+GG A + VGG                   G+S  P   P     G G   +   
Sbjct: 231 PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP 290

Query: 105 CVGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLPYQ----------RGPAGAGPGPAP 154
               P     P LPP    +          G    P            +G  G  PGP  
Sbjct: 291 PANFPH--VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348

Query: 155 GTGTAPEPRSESPS 168
           G   AP P S  P+
Sbjct: 349 GPTLAPSPHSLPPA 362



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 44/170 (25%), Positives = 55/170 (32%), Gaps = 23/170 (13%)

Query: 20  QQHMDVGPAARA--PYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEGPS------V 71
           Q H + GP      P+ L    +    P   +P  G     P GP  L    S       
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQA 561

Query: 72  GPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLP-PTL------LDQ 124
           GP G P  +     SST    YP   P  +       PQG   P  P PT+      L  
Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPS-----QGPQGAPYPFPPVPTVTTSSATLST 616

Query: 125 FEKQLPVQQDGFHTLPYQRGPAGAGPGPAPG---TGTAPEPRSESPSRIR 171
               +     G+ T      P      P+PG   T T P  +  SP   R
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFR 666


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 63/262 (24%), Positives = 91/262 (34%), Gaps = 55/262 (20%)

Query: 50  PRAGLGHISPEGPLSLSE-GPSVGPEGGPAGAGVGGGS-------STFPRMYPGQGP--- 98
           P  G  H  P  P+S+S  G S  P   P    VGGG+       + FP + P   P   
Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA 306

Query: 99  FDTCEDCVGHPQGKGAPRLP-----PTLLDQFEKQLPVQQDGFHTL---PYQRGPAGAGP 150
                +    P G GA  LP     P  + Q    LP   +   TL   P+   PA +  
Sbjct: 307 LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS- 365

Query: 151 GPAP----------GTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNG--- 197
            PAP           +  A    S S S       + Q L +  HS   P     +    
Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP 425

Query: 198 -------------------PKAEGRGGSGGDSYPGP---GSGGPHTSHHHHHHHHHHHHQ 235
                              P   GR  +  +++PGP    +G   T+H     HHHHH Q
Sbjct: 426 KYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485

Query: 236 SRHGKRSKSKDRKGDGRHQAKS 257
            +  ++ + + ++   +H   S
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNS 507



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 48/194 (24%), Positives = 60/194 (30%), Gaps = 40/194 (20%)

Query: 10  SHPRPARFADQQHMDVGPAA-RAPYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEG 68
           S PR    + + H  V P    AP    +   F   P    P   L    P G   +  G
Sbjct: 174 STPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL---YPGGTGGVLSG 230

Query: 69  PSVGPEGGPAGAGVGG-------------------GSSTFPRMYP-----GQGPFDTCED 104
           P +GP+GG A + VGG                   G+S  P   P     G G   +   
Sbjct: 231 PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP 290

Query: 105 CVGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLPYQ----------RGPAGAGPGPAP 154
               P     P LPP    +          G    P            +G  G  PGP  
Sbjct: 291 PANFPH--VTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348

Query: 155 GTGTAPEPRSESPS 168
           G   AP P S  P+
Sbjct: 349 GPTLAPSPHSLPPA 362



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 44/170 (25%), Positives = 55/170 (32%), Gaps = 23/170 (13%)

Query: 20  QQHMDVGPAARA--PYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEGPS------V 71
           Q H + GP      P+ L    +    P   +P  G     P GP  L    S       
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQA 561

Query: 72  GPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLP-PTL------LDQ 124
           GP G P  +     SST    YP   P  +       PQG   P  P PT+      L  
Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPS-----QGPQGAPYPFPPVPTVTTSSATLST 616

Query: 125 FEKQLPVQQDGFHTLPYQRGPAGAGPGPAPG---TGTAPEPRSESPSRIR 171
               +     G+ T      P      P+PG   T T P  +  SP   R
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFR 666


>gi|40288197 GATA binding protein 6 [Homo sapiens]
          Length = 595

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 20/107 (18%)

Query: 145 PAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRG 204
           P G+G G A G    P     + + +     S +  ++ S  +     R+  G  A G G
Sbjct: 234 PYGSGGGAAGGGAAGPGGAGSAAAHV-----SARFPYSPSPPMANGAAREPGGYAAAGSG 288

Query: 205 GSGGDS---------------YPGPGSGGPHTSHHHHHHHHHHHHQS 236
           G+GG S               Y    +  P    +HHHHHHHHHH S
Sbjct: 289 GAGGVSGGGSSLAAMGGREPQYSSLSAARPLNGTYHHHHHHHHHHPS 335


>gi|7710129 LIM domain only 6 [Homo sapiens]
          Length = 615

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 39/153 (25%), Positives = 55/153 (35%), Gaps = 18/153 (11%)

Query: 141 YQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHS----------LEAP 190
           + RG       P  G  + PEP  ESP +    +      F +  +           E  
Sbjct: 428 FLRGAPHRHSMPELGLRSVPEPPPESPGQPN--LRPDDSAFGRQSTPRVSFRDPLVSEGG 485

Query: 191 GKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGD 250
            +R  + P A+ R          P    P    HHHH+HHHHH++    +R    D    
Sbjct: 486 PRRTLSAPPAQRRRPRS------PPPRAPSRRRHHHHNHHHHHNRHPSRRRHYQCDAGSG 539

Query: 251 GRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEP 283
              ++ S+   SS      D GF  G R P  P
Sbjct: 540 SDSESCSSSPSSSSSESSEDDGFFLGERIPLPP 572


>gi|194248068 synaptic Ras GTPase activating protein 1 [Homo
           sapiens]
          Length = 1343

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 20/33 (60%), Positives = 23/33 (69%), Gaps = 2/33 (6%)

Query: 200 AEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHH 232
           A+G G  GG  + G G  GP +SHHHHHHHHHH
Sbjct: 936 ADGPGPPGG--HGGGGGHGPPSSHHHHHHHHHH 966



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 55/215 (25%), Positives = 75/215 (34%), Gaps = 48/215 (22%)

Query: 57   ISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMY------PGQGPFDTCEDCVGHPQ 110
            +S + PL        GP GG  G G  G  S+    +       G+ P DT     G+ +
Sbjct: 925  LSFQNPLFHMAADGPGPPGGHGGGGGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSK 984

Query: 111  GK----GAPRLP---------------PTLLDQFEKQLPVQQDGFHTL-----------P 140
             +    G P+ P               P+  D   +QL +Q +  H L           P
Sbjct: 985  SEDLSSGVPKPPAASILHSHSYSDEFGPSGTDFTRRQLSLQDNLQHMLSPPQITIGPQRP 1044

Query: 141  YQRGP-AGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGP- 198
               GP  G+G G   G G  P P     S+ +  V + QK    S +L    +  Y GP 
Sbjct: 1045 APSGPGGGSGGGSGGGGGGQPPPLQRGKSQ-QLTVSAAQKPRPSSGNLLQSPEPSY-GPA 1102

Query: 199  --------KAEGRGGSGGDSYPGPGSGGPHTSHHH 225
                    K    GGSGG    G G   P  +  H
Sbjct: 1103 RPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQH 1137



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 9/82 (10%)

Query: 3    GYHGDRGSHPRPARFADQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGHISPEGP 62
            G  G  G  P P +    Q + V  AA+ P         S EP +   R     +S EG 
Sbjct: 1056 GSGGGGGGQPPPLQRGKSQQLTVS-AAQKPRPSSGNLLQSPEPSYGPARPRQQSLSKEG- 1113

Query: 63   LSLSEGPSVGPEGGPAGAGVGG 84
                   S+G  GG  G G GG
Sbjct: 1114 -------SIGGSGGSGGGGGGG 1128


>gi|61966923 forkhead box B2 [Homo sapiens]
          Length = 432

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 19/30 (63%), Positives = 20/30 (66%), Gaps = 1/30 (3%)

Query: 210 SYPGPGSGGP-HTSHHHHHHHHHHHHQSRH 238
           S PG G GG  H  HHHH HHHHHHH + H
Sbjct: 126 SAPGAGPGGHLHPHHHHHPHHHHHHHAAAH 155


>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 2 [Homo sapiens]
          Length = 754

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 19/127 (14%)

Query: 151 GPAPGTGTAPEPRSESPSRIRH----LVHSVQKLFAKSHSLEA----PGKRDYNGPKA-- 200
           G + GT  +   RS+   + RH       +VQ +  ++HS +     P    ++G +A  
Sbjct: 507 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPT 566

Query: 201 ----EGRGGSGGDSYPGPGSGGPH-----TSHHHHHHHHHHHHQSRHGKRSKSKDRKGDG 251
               E         +  P     H     +SHHHHHHHHHHHH  +    ++++ R  + 
Sbjct: 567 QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNS 626

Query: 252 RHQAKST 258
              + ST
Sbjct: 627 PTNSSST 633


>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 1 [Homo sapiens]
          Length = 763

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 19/127 (14%)

Query: 151 GPAPGTGTAPEPRSESPSRIRH----LVHSVQKLFAKSHSLEA----PGKRDYNGPKA-- 200
           G + GT  +   RS+   + RH       +VQ +  ++HS +     P    ++G +A  
Sbjct: 516 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPT 575

Query: 201 ----EGRGGSGGDSYPGPGSGGPH-----TSHHHHHHHHHHHHQSRHGKRSKSKDRKGDG 251
               E         +  P     H     +SHHHHHHHHHHHH  +    ++++ R  + 
Sbjct: 576 QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNS 635

Query: 252 RHQAKST 258
              + ST
Sbjct: 636 PTNSSST 642


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 76/310 (24%), Positives = 102/310 (32%), Gaps = 68/310 (21%)

Query: 143  RGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSH----------------- 185
            RG  G+G G +PG G       +SPS  RH   S +   +  H                 
Sbjct: 880  RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSG 939

Query: 186  ----------------SLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHH 229
                            S E  G R     ++E  G S G S     S G H S       
Sbjct: 940  QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSS----SSYGQHGSGSRQSLG 995

Query: 230  HHHHHQSRHGKRSKSKDRKGDGRHQAKS-------TGWWSSDDNLDSDSGFLAGGRPPGE 282
            H  H        S S+ R G G  Q+ S       +GW SS    +S SG  +G      
Sbjct: 996  HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRES 1055

Query: 283  PGGPFCLEGPDGSYR-DLSFKGRSGGSEGRCLACTGMSMSLDGQSV---KRSAWHTMMVS 338
              G     G  GS     S  G+ G + G+  +C G   +  GQS    +  +  +    
Sbjct: 1056 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC-GQHGASSGQSSSHGQHGSGSSQSSG 1114

Query: 339  QGRDGY-PGAGPGKGLLGPETKAKARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSY 397
             GR G   G  PG G  G  ++                   P+ G+ G    R   SG +
Sbjct: 1115 YGRQGSGSGQSPGHGQRGSGSRQS-----------------PSYGRHGSGSGRSSSSGQH 1157

Query: 398  IKAMGDEESG 407
               +G E SG
Sbjct: 1158 GSGLG-ESSG 1166



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 76/308 (24%), Positives = 98/308 (31%), Gaps = 38/308 (12%)

Query: 51   RAGLGHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPR-----MYPGQGPFDTCEDC 105
            R  LGH    G      G S  P  G  G+G G  SS  P          +GP+++    
Sbjct: 2401 RQSLGH----GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGS-- 2454

Query: 106  VGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSE 165
             GH  G G             +    Q  G+       G  G+  G +   G       +
Sbjct: 2455 -GHSSGLG-----------HRESRSGQSSGY-------GQHGSSSGHSSTHGQHGSTSGQ 2495

Query: 166  SPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGS--GGPHTSH 223
            S S  +H   S Q   + SH     G    +G    GR GSG    PG G    G   S 
Sbjct: 2496 SSSCGQHGASSGQ---SSSHGQHGSGSSQSSG---YGRQGSGSGQSPGHGQRGSGSRQSP 2549

Query: 224  HHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEP 283
             +  H       S  G+            H   S+G  SS     S SG  +G    G  
Sbjct: 2550 SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2609

Query: 284  GGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRDG 343
             G        GS    S      GS  R  +  G   S  GQS  R    + +      G
Sbjct: 2610 SGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 2669

Query: 344  YPGAGPGK 351
              G+G G+
Sbjct: 2670 QHGSGSGR 2677



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 71/276 (25%), Positives = 95/276 (34%), Gaps = 40/276 (14%)

Query: 144  GPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGR 203
            G  G+G G + G G       +S    +H   S       S S E  G R     + E  
Sbjct: 1859 GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS-----GHSSSYEQHGSRSGQSSRGEQH 1913

Query: 204  GGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKS------ 257
            G S G S     S G H S       H  H        S S+ R G G  Q+ S      
Sbjct: 1914 GSSSGSS----SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGS 1969

Query: 258  -TGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYR-DLSFKGRSGGSEGRCLAC 315
             +GW SS    +S SG  +G        G     G  GS     S  G+ G + G+  +C
Sbjct: 1970 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC 2029

Query: 316  TGMSMSLDGQSV---KRSAWHTMMVSQGRDGY-PGAGPGKGLLGPETKAKARTYHYLQVP 371
             G   +  GQS    +  +  +     GR G   G  PG G  G  ++            
Sbjct: 2030 -GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS---------- 2078

Query: 372  QDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESG 407
                   P+ G+ G    R   SG +   +G E SG
Sbjct: 2079 -------PSYGRHGSGSGRSSSSGQHGPGLG-ESSG 2106



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 75/308 (24%), Positives = 98/308 (31%), Gaps = 38/308 (12%)

Query: 51   RAGLGHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPR-----MYPGQGPFDTCEDC 105
            R  LGH    G      G S  P  G  G+G G  SS  P          +GP+++    
Sbjct: 1461 RQSLGH----GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSS- 1515

Query: 106  VGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSE 165
              H  G G             +    Q  G+       G  G+  G +   G       +
Sbjct: 1516 --HSSGLG-----------HRESRSGQSSGY-------GQHGSSSGHSSTHGQHGSTSGQ 1555

Query: 166  SPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGS--GGPHTSH 223
            S S  +H   S Q   + SH     G    +G    GR GSG    PG G    G   S 
Sbjct: 1556 SSSCGQHGASSGQ---SSSHGQHGSGSSQSSG---YGRQGSGSGQSPGHGQRGSGSRQSP 1609

Query: 224  HHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEP 283
             +  H       S  G+            H   S+G  SS     S SG  +G    G  
Sbjct: 1610 SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1669

Query: 284  GGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRDG 343
             G        GS    S +    GS  R  +  G   S  GQS  R    + +      G
Sbjct: 1670 SGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 1729

Query: 344  YPGAGPGK 351
              G+G G+
Sbjct: 1730 QHGSGSGR 1737



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 49/180 (27%), Positives = 63/180 (35%), Gaps = 4/180 (2%)

Query: 147 GAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGS 206
           G+G G + G G       +S    RH   S     + S+     G R   G   +G G  
Sbjct: 248 GSGSGHSSGYGQHGSRSGQSSRGERHRSSSGS---SSSYGQHGSGSRQSLGHGRQGSGSR 304

Query: 207 GGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDN 266
              S+   GSG  H+S H  H     +  SR    S S    G G+H++ S G  S    
Sbjct: 305 QSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS-GQSSGYSK 363

Query: 267 LDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQS 326
             S SG  +     G   G     G  GS    S       S  R  +  G   S  GQS
Sbjct: 364 HGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQS 423



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 95/394 (24%), Positives = 130/394 (32%), Gaps = 50/394 (12%)

Query: 51   RAGLGHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFP-RMYPG----QGPFDTCEDC 105
            R  LGH    G      G S  P  G  G+G G  SS  P R   G    +GP+++    
Sbjct: 991  RQSLGH----GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGS-- 1044

Query: 106  VGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSE 165
             GH  G G             +    Q  G+       G  G+  G +   G       +
Sbjct: 1045 -GHSSGLG-----------HRESRSGQSSGY-------GQHGSSSGHSSTHGQHGSTSGQ 1085

Query: 166  SPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGS--GGPHTSH 223
            S S  +H   S Q   + SH     G    +G    GR GSG    PG G    G   S 
Sbjct: 1086 SSSCGQHGASSGQ---SSSHGQHGSGSSQSSG---YGRQGSGSGQSPGHGQRGSGSRQSP 1139

Query: 224  HHHHHHHHHHHQSRHGKRSKSK-DRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGE 282
             +  H       S  G+      +  G G H++ S+G  SS     S SG  +G    G 
Sbjct: 1140 SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES-SSGQSSSYSQHGSGSGHSSGYGQHGS 1198

Query: 283  PGGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRD 342
              G        GS    S      GS  R  +  G   S  G S  R    + +      
Sbjct: 1199 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSH 1258

Query: 343  GYPGAGPGKGLLGPETKAKARTYHYLQVPQDDWG-----GYPTGGKDGEIPCRRMRSGSY 397
            G  G+G G+         ++R+ H     Q + G      Y   G      C + + GS 
Sbjct: 1259 GQHGSGSGRS--SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS- 1315

Query: 398  IKAMGDEESGDSDGSPKTSPKAVARRFTTRRSSS 431
                G   + D +GS      +   R +    SS
Sbjct: 1316 --TSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS 1347



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 70/276 (25%), Positives = 94/276 (34%), Gaps = 40/276 (14%)

Query: 144  GPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGR 203
            G  G+G G + G G       +S    +H   S       S S E  G R     + E  
Sbjct: 1389 GRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGS-----GHSSSYEQHGSRSGQSSRGERH 1443

Query: 204  GGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKS------ 257
            G S G S     S G H S       H  H        S S+ R G G  Q+ S      
Sbjct: 1444 GSSSGSS----SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS 1499

Query: 258  -TGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYR-DLSFKGRSGGSEGRCLAC 315
             +GW SS    +S S   +G        G     G  GS     S  G+ G + G+  +C
Sbjct: 1500 GSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 1559

Query: 316  TGMSMSLDGQSV---KRSAWHTMMVSQGRDGY-PGAGPGKGLLGPETKAKARTYHYLQVP 371
             G   +  GQS    +  +  +     GR G   G  PG G  G  ++            
Sbjct: 1560 -GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS---------- 1608

Query: 372  QDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESG 407
                   P+ G+ G    R   SG +   +G E SG
Sbjct: 1609 -------PSYGRHGSGSGRSSSSGQHGSGLG-ESSG 1636



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 62/212 (29%), Positives = 78/212 (36%), Gaps = 15/212 (7%)

Query: 144 GPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYN--GPKAE 201
           G  G+G   + G G        SPSR+RH   S     + SH     G    +  G    
Sbjct: 753 GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGH---SSSHGQHGSGTSCSSSCGHYES 809

Query: 202 GRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWW 261
           G G + G      GSG  ++   H     H   Q RHG  S S      G+H + S+G  
Sbjct: 810 GSGQASGFGQHESGSGQGYS--QHGSASGHFSSQGRHG--STSGQSSSSGQHDS-SSGQS 864

Query: 262 SSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLS-FKGRSGGSEGRCLACTGMSM 320
           SS    +S S   +G    G   G     G  GS    S   GR G   GR  + +G   
Sbjct: 865 SSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRS-SSSGRHG 923

Query: 321 SLDGQSVKRSAWHTMMVSQGRDGYPGAGPGKG 352
           S  GQS   S +     S    GY   G G G
Sbjct: 924 SGSGQS---SGFGHKSSSGQSSGYTQHGSGSG 952



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 51/204 (25%), Positives = 68/204 (33%), Gaps = 4/204 (1%)

Query: 147  GAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGS 206
            G+G G + G G       +S    RH   S     +  +     G R  +G   +G G  
Sbjct: 2124 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGS---SSRYGQHGSGSRQSSGHGRQGSGSG 2180

Query: 207  GGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDN 266
               S    GSG  H+S H  H        SR    S+S      G+H++ S G  S+   
Sbjct: 2181 HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS-GHSSAYSQ 2239

Query: 267  LDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQS 326
              S SG        G   G       +GS    S      GS     +  G   S  GQS
Sbjct: 2240 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 2299

Query: 327  VKRSAWHTMMVSQGRDGYPGAGPG 350
              R    +        G  G+G G
Sbjct: 2300 PSRGRHGSGSGHSSSYGQHGSGSG 2323



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/391 (22%), Positives = 121/391 (30%), Gaps = 59/391 (15%)

Query: 5    HGDRGSHPRPARFADQQHMDVGPA---ARAPYLLGSREAFSTEPRFCAPRAGLGHISPEG 61
            +G  GS  R +    Q     G +   +R  +  GS ++ S  P     R+G G  S  G
Sbjct: 983  YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY----RSGSGWSSSRG 1038

Query: 62   PLSLSEGPSVG------PEGGPAGAGVGGGSSTFPRMYPGQGPFD-TCEDCVGHPQGKGA 114
            P     G S G        G  +G G  G SS     +   G        C  H    G 
Sbjct: 1039 PYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG- 1097

Query: 115  PRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLV 174
                       +     Q     +     G  G+G G +PG G       +SPS  RH  
Sbjct: 1098 -----------QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 1146

Query: 175  HSVQKLFAKSHSL------------EAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTS 222
             S +   +  H               + G+         G G S G    G  SG     
Sbjct: 1147 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1206

Query: 223  HHHHHHHHHHHHQSRHG---KRSKSKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRP 279
              H        H  +HG   ++S    R+G G   + S G   S     S  G    G  
Sbjct: 1207 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSG 1266

Query: 280  PGEPGGPF-----------CLEGPDGSYRDLSFKGRSGG---SEGRCLACTGMSMSLD-- 323
                 GP+             E   G     S  G   G   S+G+  + +G S + D  
Sbjct: 1267 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 1326

Query: 324  GQSVKRSA--WHTMMVSQGRDGYPGAGPGKG 352
            G S  +S+   H    S    GY   G G G
Sbjct: 1327 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG 1357



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 51/204 (25%), Positives = 68/204 (33%), Gaps = 4/204 (1%)

Query: 147  GAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGS 206
            G+G G + G G   +  S S    R   H      +  +     G R  +G   +G G  
Sbjct: 1654 GSGSGHSSGYG---QHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSG 1710

Query: 207  GGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDN 266
               S    GSG  H+S H  H        SR    S+S      G+H++ S G  S+   
Sbjct: 1711 QSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS-GHSSAYSQ 1769

Query: 267  LDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQS 326
              S SG        G   G       +GS    S      GS     +  G   S  GQS
Sbjct: 1770 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 1829

Query: 327  VKRSAWHTMMVSQGRDGYPGAGPG 350
              R    +        G  G+G G
Sbjct: 1830 PSRGRHGSGSGHSSSYGQHGSGSG 1853



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 54/210 (25%), Positives = 68/210 (32%), Gaps = 28/210 (13%)

Query: 147  GAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGS 206
            G+G G + G G       +S    RH   S        H     G R  +G   +G G  
Sbjct: 1184 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHG---SGSRQSSGHGRQGSGSG 1240

Query: 207  GGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDN 266
               S    GSG  H+S H  H        SR    S+S      G+H             
Sbjct: 1241 HSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH------------- 1287

Query: 267  LDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQS 326
             +S SG  +     G   G FC +G  GS    S      GS       TG S S     
Sbjct: 1288 -ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS------TGQSSSYG--- 1337

Query: 327  VKRSAWHTMMVSQGRDGY-PGAGPGKGLLG 355
              R +  +     GR G   G  P +G  G
Sbjct: 1338 -HRGSGSSQSSGYGRHGAGSGQSPSRGRHG 1366



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 83/344 (24%), Positives = 104/344 (30%), Gaps = 58/344 (16%)

Query: 35   LGSREAFSTEPR-FCAPRAGLGHISPEGPLSLSEGPS--VGPEGGPAGAGVGGG------ 85
            LG RE+ S +   +    +  GH S  G    + G S   G  G  +G     G      
Sbjct: 2460 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 2519

Query: 86   --SSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLPYQR 143
              SS + R   G G         GH Q     R  P+              G H      
Sbjct: 2520 SQSSGYGRQGSGSG------QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH------ 2567

Query: 144  GPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGR 203
               G+G G + G G       +S S  +H   S        H     G R     + E  
Sbjct: 2568 ---GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH-----GSRSGQSSRGERH 2619

Query: 204  GGSGGDS--YPGPGSGGPHTSHHHHH------------HHHHHHHQSRHGKRSKSKDRKG 249
            G S G S  Y   GSG   +S H               H     H S HG+      R  
Sbjct: 2620 GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 2679

Query: 250  DGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSE 309
                     G  S     +S SG  +     G   G FC +G  GS    S      GS 
Sbjct: 2680 SRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS 2739

Query: 310  GRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPGKGL 353
                  TG S S       R +  +     GR    GAG G+ L
Sbjct: 2740 ------TGQSSSYG----HRGSGSSQSSGYGRH---GAGSGQSL 2770



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 48/178 (26%), Positives = 60/178 (33%), Gaps = 32/178 (17%)

Query: 143 RGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEG 202
           RG   +G G +PG G       +SPS  +H        F +S S         +GP   G
Sbjct: 413 RGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG-----FGRSSS---------SGPYVSG 458

Query: 203 RGGSGGDSYPGPGSGGPHTSHHHHHHHHHHH-----HQSRHGKRSKSKDRKGDGRHQAKS 257
            G S G         G H S   H   +  H     H S HG+      +   G  Q  S
Sbjct: 459 SGYSSGF--------GHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSS 510

Query: 258 TGWWSSDDNLDSDS----GFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGR 311
            G  SS     S S    G    G   G+   P       GS +  S+ G  G   GR
Sbjct: 511 AGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSY-GPHGYGSGR 567



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 65/264 (24%), Positives = 86/264 (32%), Gaps = 15/264 (5%)

Query: 64  SLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQGKGAPRLPPTLLD 123
           S S GP V   G  +G G    SS     Y   G         GH  G G          
Sbjct: 449 SSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGS------GHSSGHGQHGSRSGQSS 502

Query: 124 QFEKQLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAK 183
           + E+Q            +  G   +      G+G+   P   SPSR RH   S Q     
Sbjct: 503 RGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSP---SPSRGRHESGSRQSSSYG 559

Query: 184 SHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSK 243
            H   + G+    GP   G G S G  +    SG    S  +  H     H S HG+   
Sbjct: 560 PHGYGS-GRSSSRGPYESGSGHSSGLGHQESRSG---QSSGYGQHGSSSGHSSTHGQHGS 615

Query: 244 SKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGS-YRDLSFK 302
           +  +         ++G  SS     S S   +     G   G     G  GS +   S  
Sbjct: 616 TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSY 675

Query: 303 GRSGGSEGRCLACTGMSMSLDGQS 326
           G+ G   G   +  G   S+ GQS
Sbjct: 676 GQHGSGSG-WSSSNGPHGSVSGQS 698



 Score = 38.1 bits (87), Expect = 0.041
 Identities = 54/221 (24%), Positives = 73/221 (33%), Gaps = 30/221 (13%)

Query: 144 GPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQK------------LFAKSHSLEAPG 191
           G  G+G   + G G       +SPS +RH   S                +++ H     G
Sbjct: 284 GQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSG 343

Query: 192 KRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDG 251
           +    G    G G S G S  G GSG   +   H           +HG  S S+     G
Sbjct: 344 QTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHG--SSSRQSSSYG 401

Query: 252 RHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGR 311
           +H++ S    S      S SG   G    G   G    + P        F GRS  S G 
Sbjct: 402 QHESASR-HSSGRGQHSSGSGQSPGHGQRGSGSG----QSPSSGQHGTGF-GRS-SSSGP 454

Query: 312 CLACTGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPGKG 352
            ++ +G S             H    S+   GY   G G G
Sbjct: 455 YVSGSGYSSGFG---------HHESSSEHSSGYTQHGSGSG 486



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 56/221 (25%), Positives = 71/221 (32%), Gaps = 43/221 (19%)

Query: 144  GPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGR 203
            G  G+G G +PG G       +SPS  RH                             G 
Sbjct: 2056 GRQGSGSGQSPGHGQRGSGSRQSPSYGRH---------------------------GSGS 2088

Query: 204  GGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSS 263
            G S      GPG G      HH          S+HG  S S    G G+H ++S G  S 
Sbjct: 2089 GRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHG--SGSGHSSGYGQHGSRS-GQSSR 2145

Query: 264  DDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLS-FKGRSGGSEGRCLACTGMSMSL 322
             +   S SG  +     G         G  GS    S  +GR G   G   +  G   S 
Sbjct: 2146 GERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHS-SSHGQHGSG 2204

Query: 323  DGQSVKRSAW-----HTMMVSQGRDG------YPGAGPGKG 352
             G+S  R  +     H+ +  Q   G      Y   G G G
Sbjct: 2205 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 2245



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 87/373 (23%), Positives = 110/373 (29%), Gaps = 35/373 (9%)

Query: 52   AGLGHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQG 111
            +GLGH S  G      G S     GP  +   G SS F +   G G          H  G
Sbjct: 1250 SGLGHSSSHGQHGSGSGRS--SSRGPYESR-SGHSSVFGQHESGSGHSSAYSQ---HGSG 1303

Query: 112  KGAPRLPPTLLDQFEKQLPVQQDGFHT-LPYQRGPAGAGPGPAPGTGTAPEPRSESPSRI 170
             G             +     Q+G  T      G  G+G   + G G       +SPSR 
Sbjct: 1304 SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRG 1363

Query: 171  RHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHH 230
            RH   S        H     G    +G    G G S G  +    S        H     
Sbjct: 1364 RHGSGSGHSSSYGQHG-SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSG 1422

Query: 231  HHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLE 290
            H     +HG RS    R   G     S+G  SS     S S    G    G   G    +
Sbjct: 1423 HSSSYEQHGSRSGQSSR---GERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG----Q 1475

Query: 291  GPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQSVKRSAWHTMMVSQGRDGYPGAGPG 350
             P  S      +GR G   G+       S S  G     S W     S  R  Y      
Sbjct: 1476 SPSPS------RGRHGSGSGQ-----SSSYSPYGSG---SGW-----SSSRGPYESGSSH 1516

Query: 351  KGLLGPETKAKARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGDEESGDSD 410
               LG       ++  Y Q      G   T G+ G    +    G +  + G   S    
Sbjct: 1517 SSGLGHRESRSGQSSGYGQHGSSS-GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH 1575

Query: 411  GSPKTSPKAVARR 423
            GS  +      R+
Sbjct: 1576 GSGSSQSSGYGRQ 1588



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 64/260 (24%), Positives = 88/260 (33%), Gaps = 22/260 (8%)

Query: 182  AKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQS--RHG 239
            + SH     G    +    +G G     S    GSG  H+S +  H        S  RHG
Sbjct: 2273 SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHG 2332

Query: 240  KRSKSKDRKGDGRHQAKS------------TGWWSSDDNLDSDSGFLAGGRPPGEPGGPF 287
              S S    G G H++ S            +G  SS +   S SG  + G   G   G  
Sbjct: 2333 --SGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 2390

Query: 288  CLEGPDGS-YRDLSFKGRSGGSEGRCLA-CTGMSMSLDGQSVKRSAWHT-MMVSQGRDGY 344
               G  GS  R     G+ G   G+  +   G   S  GQS   S + +    S  R  Y
Sbjct: 2391 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPY 2450

Query: 345  -PGAGPGKGLLGPETKAKARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSYIKAMGD 403
              G+G   G LG       ++  Y Q      G   T G+ G    +    G +  + G 
Sbjct: 2451 ESGSGHSSG-LGHRESRSGQSSGYGQHGSSS-GHSSTHGQHGSTSGQSSSCGQHGASSGQ 2508

Query: 404  EESGDSDGSPKTSPKAVARR 423
              S    GS  +      R+
Sbjct: 2509 SSSHGQHGSGSSQSSGYGRQ 2528



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 66/266 (24%), Positives = 88/266 (33%), Gaps = 34/266 (12%)

Query: 182  AKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQS--RHG 239
            + SH     G    +    +G G     S    GSG  H+S +  H        S  RHG
Sbjct: 1803 SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHG 1862

Query: 240  KRSKSKDRKGDGRHQAKS------------TGWWSSDDNLDSDSGFLAGGRPPGEPGGPF 287
              S S    G G H++ S            +G  SS +   S SG  + G   G   G  
Sbjct: 1863 --SGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSS 1920

Query: 288  CLEGPDGS-YRDLSFKGRSGG--------SEGRCLACTGMSMSLDGQSVKRSAWHTMMVS 338
               G  GS  R     G+ G         S GR  + +G S S  G     S W     S
Sbjct: 1921 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY-GPYGSGSGW-----S 1974

Query: 339  QGRDGY-PGAGPGKGLLGPETKAKARTYHYLQVPQDDWGGYPTGGKDGEIPCRRMRSGSY 397
              R  Y  G+G   G LG       ++  Y Q      G   T G+ G    +    G +
Sbjct: 1975 SSRGPYESGSGHSSG-LGHRESRSGQSSGYGQHGSSS-GHSSTHGQHGSASGQSSSCGQH 2032

Query: 398  IKAMGDEESGDSDGSPKTSPKAVARR 423
              + G   S    GS  +      R+
Sbjct: 2033 GASSGQSSSHGQHGSGSSQSSGYGRQ 2058



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 45/199 (22%), Positives = 64/199 (32%), Gaps = 12/199 (6%)

Query: 164 SESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGPHTSH 223
           S S    R   H      + S+     G    +G   +G G     S    GS   H+S 
Sbjct: 731 SRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSS 790

Query: 224 HHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKS----------TGWWSSDDNLDSDSG- 272
           H  H        S     S S    G G+H++ S          +G +SS     S SG 
Sbjct: 791 HGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQ 850

Query: 273 FLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQSVKRSAW 332
             + G+     G        + +    S +GR G   G+     G   S  GQS      
Sbjct: 851 SSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPG-HGQRGSGSGQSPSYGRH 909

Query: 333 HTMMVSQGRDGYPGAGPGK 351
            +        G  G+G G+
Sbjct: 910 GSGSGRSSSSGRHGSGSGQ 928



 Score = 32.0 bits (71), Expect = 2.9
 Identities = 54/209 (25%), Positives = 67/209 (32%), Gaps = 12/209 (5%)

Query: 147 GAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGS 206
           G+G G + G G     RS   SR      S     + S+     G R   G     R GS
Sbjct: 482 GSGSGHSSGHGQHGS-RSGQSSRGERQGSSAGS--SSSYGQHGSGSRQSLG---HSRHGS 535

Query: 207 GGDSYPGPG-----SGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWW 261
           G    P P      SG   +S +  H +      SR    S S    G G HQ   +G  
Sbjct: 536 GSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLG-HQESRSGQS 594

Query: 262 SSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMS 321
           S      S SG  +     G   G     G  G+    S      GS     +  G   S
Sbjct: 595 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGS 654

Query: 322 LDGQSVKRSAWHTMMVSQGRDGYPGAGPG 350
             GQS  R    +        G  G+G G
Sbjct: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSG 683



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 81/382 (21%), Positives = 111/382 (29%), Gaps = 48/382 (12%)

Query: 5   HGDRGSHPRPARFADQQHMDVGPAARA-PYLLGS---------REAFSTEPRFCAPRAGL 54
           HG RGS    +  + Q     G ++ + PY+ GS           +      +    +G 
Sbjct: 426 HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGS 485

Query: 55  GHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQ-GKG 113
           GH S  G      G S    G   G+  G  SS     Y   G        +GH + G G
Sbjct: 486 GHSSGHGQHGSRSGQS--SRGERQGSSAGSSSS-----YGQHG--SGSRQSLGHSRHGSG 536

Query: 114 APRLPPTLLDQFEKQLPVQQDGFHTLPY------QRGPAGAGPGPAPGTGTAPEPRSESP 167
           + + P     + E     Q   +    Y       RGP  +G G + G G       +S 
Sbjct: 537 SGQSPSPSRGRHESGSR-QSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSS 595

Query: 168 SRIRHLVHSVQKLFAKSHSLEA------------PGKRDYNGPKAEGRGGSGGDSYPGPG 215
              +H   S        H   +             G+   +G    G   S      G G
Sbjct: 596 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSG 655

Query: 216 SGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKG---------DGRHQAKSTGWWSSDDN 266
           SG   +   H     H     +HG  S      G          G      +G  S    
Sbjct: 656 SGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQ 715

Query: 267 LDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCLACTGMSMSLDGQS 326
             S S   +G R  G   G        GS   LS      GS     +  G   S  G S
Sbjct: 716 HGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHS 775

Query: 327 VKRSAWHTMMVSQGRDGYPGAG 348
             R    +        G  G+G
Sbjct: 776 PSRVRHGSSSGHSSSHGQHGSG 797


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 33/97 (34%), Positives = 36/97 (37%), Gaps = 21/97 (21%)

Query: 144 GPAGAGPGPAPGTGTAP------EPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNG 197
           G A AG GPA     AP      E R        H           S +    G +D   
Sbjct: 586 GAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHH-----------SSAFRPVGGKDDAE 634

Query: 198 PKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHH 234
             A+  G S G     P S   H  HHHH HHHHHHH
Sbjct: 635 SLAKLHGASAG----APHSAQTHPHHHHHPHHHHHHH 667



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 10/51 (19%)

Query: 213 GPGSGGPHTS--HHHHHHHHHHHHQSRHGKRSKS--------KDRKGDGRH 253
           G  +G PH++  H HHHHH HHHH   H  +  S         D  G  RH
Sbjct: 641 GASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERH 691


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 33/97 (34%), Positives = 36/97 (37%), Gaps = 21/97 (21%)

Query: 144 GPAGAGPGPAPGTGTAP------EPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNG 197
           G A AG GPA     AP      E R        H           S +    G +D   
Sbjct: 586 GAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHH-----------SSAFRPVGGKDDAE 634

Query: 198 PKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHH 234
             A+  G S G     P S   H  HHHH HHHHHHH
Sbjct: 635 SLAKLHGASAG----APHSAQTHPHHHHHPHHHHHHH 667



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 10/51 (19%)

Query: 213 GPGSGGPHTS--HHHHHHHHHHHHQSRHGKRSKS--------KDRKGDGRH 253
           G  +G PH++  H HHHHH HHHH   H  +  S         D  G  RH
Sbjct: 641 GASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERH 691


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 33/97 (34%), Positives = 36/97 (37%), Gaps = 21/97 (21%)

Query: 144 GPAGAGPGPAPGTGTAP------EPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNG 197
           G A AG GPA     AP      E R        H           S +    G +D   
Sbjct: 586 GAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHH-----------SSAFRPVGGKDDAE 634

Query: 198 PKAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHH 234
             A+  G S G     P S   H  HHHH HHHHHHH
Sbjct: 635 SLAKLHGASAG----APHSAQTHPHHHHHPHHHHHHH 667



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 10/51 (19%)

Query: 213 GPGSGGPHTS--HHHHHHHHHHHHQSRHGKRSKS--------KDRKGDGRH 253
           G  +G PH++  H HHHHH HHHH   H  +  S         D  G  RH
Sbjct: 641 GASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERH 691


>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
          Length = 908

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 15/24 (62%), Positives = 20/24 (83%)

Query: 219 PHTSHHHHHHHHHHHHQSRHGKRS 242
           PH  HHHHHHHHHHHH+++  ++S
Sbjct: 336 PHHHHHHHHHHHHHHHRAQPPQQS 359



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 14/19 (73%), Positives = 14/19 (73%)

Query: 219 PHTSHHHHHHHHHHHHQSR 237
           P   HHHHHHHHHHHH  R
Sbjct: 334 PPPHHHHHHHHHHHHHHHR 352



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 2/49 (4%)

Query: 223 HHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDNLDSDS 271
           HHHHHHHHHHHH   H +    +       H        S  ++  SDS
Sbjct: 337 HHHHHHHHHHHH--HHHRAQPPQQSHHPPHHHRPQPHLGSFPESCSSDS 383



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 15/34 (44%), Positives = 16/34 (47%), Gaps = 10/34 (29%)

Query: 212 PGPGSGGPHTSHHHHHHH--------HH--HHHQ 235
           P P     H  HHHHHHH        HH  HHH+
Sbjct: 334 PPPHHHHHHHHHHHHHHHRAQPPQQSHHPPHHHR 367


>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
          Length = 304

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 13/41 (31%)

Query: 220 HTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKSTGW 260
           H  HHHHHHHHHHHH  +              +HQA  T W
Sbjct: 65  HRGHHHHHHHHHHHHHQQQ-------------QHQALQTNW 92


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 84/319 (26%), Positives = 104/319 (32%), Gaps = 42/319 (13%)

Query: 3   GYHGDRGSHPRPARFADQQHMDVGPAARAPYLLGSREAFSTEPRFCAPRAGLGHISPEGP 62
           G  G +GS   P R  +            P L G+R   +  P    P   LG +   G 
Sbjct: 549 GSSGPKGSQGDPGRPGE------------PGLPGAR-GLTGNPGVQGPEGKLGPLGAPGE 595

Query: 63  LSLSEGP-SVGPEGGPAGAGVGG--GSSTFPRMYPGQGPFDTCEDCVGHPQ-----GKGA 114
                 P S+G  G P   G+ G  GSS  P   PG+          G P      G   
Sbjct: 596 DGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGK-PGEAGNAGVPGQRGAPGKDGEVGPSG 654

Query: 115 PRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAGAGPGP----APGTGTAPEPRSESPSRI 170
           P  PP L  +  +Q P    GF  LP   GP G G  P     PG   A  P      R 
Sbjct: 655 PVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERG 714

Query: 171 RHLVHSVQKLFAKSHSLEAPGKRDYNGPK-AEGRGGSGGDSYPGPGSGGPHTSHHHHHHH 229
                    +          G    +GPK + G  G+ GD+ P    G P          
Sbjct: 715 NPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP---------- 764

Query: 230 HHHHHQSRHGKRSKSKDRKGDGRHQAKSTGWWSSDDNLDSDSGFLAGGRPPGEPG--GPF 287
                +   G      DR G G   A+ T        L    G      P GE G  GP 
Sbjct: 765 ---GERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPR 821

Query: 288 CLEGPDGSYRDLSFKGRSG 306
            L GP GS  +   +G +G
Sbjct: 822 GLVGPPGSRGNPGSRGENG 840



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 51/172 (29%), Positives = 59/172 (34%), Gaps = 33/172 (19%)

Query: 55  GHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQ----GPFDTCEDCVGHPQ 110
           GH   EGP      P    E GP G  +G      PR  PG+    GP        G P 
Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTGP-MGAMGPLGPRGMPGERGRLGP-------QGAPG 354

Query: 111 GKGAPRLPPTLLDQFEKQLPVQQDGFHTLPYQRGPAG--AGPGPAPGTGTAPEPRSESPS 168
            +GA  +P          +P    GF   P  +G AG     GP    G   E     P 
Sbjct: 355 QRGAHGMPGKPGPMGPLGIP-GSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP- 412

Query: 169 RIRHLVHSVQKLFAKSHSLEAPGKRDYNG-PKAEGRGGSGGDSYPGPGSGGP 219
                            S   PG    +G P A+G  GS G S P PGS GP
Sbjct: 413 ---------------VGSPGLPGAIGTDGTPGAKGPTGSPGTSGP-PGSAGP 448


>gi|134288896 hypothetical protein LOC143684 [Homo sapiens]
          Length = 339

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 220 HTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDG 251
           H  HHHHHHHHHH H S H K S     +  G
Sbjct: 168 HPKHHHHHHHHHHRHSSSHHKISNLSPEEEQG 199



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 12/16 (75%), Positives = 12/16 (75%)

Query: 223 HHHHHHHHHHHHQSRH 238
           HH  HHHHHHHH  RH
Sbjct: 167 HHPKHHHHHHHHHHRH 182



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 19/63 (30%), Positives = 23/63 (36%), Gaps = 2/63 (3%)

Query: 199 KAEGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKST 258
           K + +  S G S+    S        HH  HHHHHH   H  R  S   K       +  
Sbjct: 141 KTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHH--RHSSSHHKISNLSPEEEQ 198

Query: 259 GWW 261
           G W
Sbjct: 199 GLW 201


>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
           b [Homo sapiens]
          Length = 637

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 16/28 (57%), Positives = 19/28 (67%)

Query: 215 GSGGPHTSHHHHHHHHHHHHQSRHGKRS 242
           G    +  HHHHHHHHHHHHQ +H + S
Sbjct: 100 GRAPSYHHHHHHHHHHHHHHQQQHQQPS 127



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 12/27 (44%), Positives = 13/27 (48%)

Query: 220 HTSHHHHHHHHHHHHQSRHGKRSKSKD 246
           H  HHHHHHH   H Q      S  +D
Sbjct: 110 HHHHHHHHHHQQQHQQPSIPPASSPED 136


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,850,555
Number of Sequences: 37866
Number of extensions: 3277427
Number of successful extensions: 26265
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 549
Number of HSP's that attempted gapping in prelim test: 19005
Number of HSP's gapped (non-prelim): 5849
length of query: 979
length of database: 18,247,518
effective HSP length: 112
effective length of query: 867
effective length of database: 14,006,526
effective search space: 12143658042
effective search space used: 12143658042
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.