Guide to the Human Genome
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Name: DYRK1A Sequence: fasta or formatted (763aa) NCBI GI: 18765758
Description:

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 1

Referenced in:

Protein Composition and Structure
Dual-Specificity Protein Kinases

Other entries for this name:
alt prot [584aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [754aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [540aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [529aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         45           2
 C cysteine            1.2          9           1
 D aspartate           4.8         37           3
 E glutamate           4.3         33           2
 F phenylalanine       3.1         24           2
 G glycine             6.9         53           2
 H histidine           6.2         47          13
 I isoleucine          3.8         29           2
 K lysine              5.2         40           3
 L leucine             7.1         54           2
 M methionine          3.3         25           1
 N asparagine          4.7         36           1
 P proline             5.2         40           2
 Q glutamine           6.8         52           2
 R arginine            5.2         40           2
 S serine              9.8         75           4
 T threonine           6.7         51           2
 V valine              5.1         39           2
 W tryptophan          0.7          5           1
 Y tyrosine            3.8         29           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   dual-specificity tyrosine-(Y)-phosphorylation regula... 
DYRK1A                0.984   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.723   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.665   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.662   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1B                0.473   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK1B                0.434   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK1B                0.422   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK4                 0.167   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK2                 0.163   dual-specificity tyrosine-(Y)-phosphorylation regul...
DYRK2                 0.163   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK3                 0.162   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK3                 0.162   dual-specificity tyrosine-(Y)-phosphorylation regula...
HIPK2                 0.127   homeodomain interacting protein kinase 2 isoform 2 ...
HIPK2                 0.127   homeodomain interacting protein kinase 2 isoform 1 ...
HIPK1                 0.127   homeodomain-interacting protein kinase 1 isoform 1 [...
HIPK1                 0.127   homeodomain-interacting protein kinase 1 isoform 2 [...
HIPK3                 0.123   homeodomain interacting protein kinase 3 isoform 2 ...
HIPK3                 0.123   homeodomain interacting protein kinase 3 isoform 1 ...
HIPK4                 0.113   homeodomain interacting protein kinase 4 
CLK1                  0.095   CDC-like kinase 1 isoform 2 
CLK1                  0.095   CDC-like kinase 1 isoform 1 
CLK4                  0.095   CDC-like kinase 4 
CLK2                  0.094   CDC-like kinase 2 
CLK3                  0.094   CDC-like kinase 3 isoform a 
CLK3                  0.094   CDC-like kinase 3 isoform b 
PRPF4B                0.093   serine/threonine-protein kinase PRP4K 
LOC653052             0.072   PREDICTED: similar to homeodomain interacting prote...
CDKL5                 0.071   cyclin-dependent kinase-like 5 
CDKL5                 0.071   cyclin-dependent kinase-like 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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