Guide to the Human Genome
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Name: DYRK1A Sequence: fasta or formatted (754aa) NCBI GI: 18765752
Description:

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A isoform 2

Referenced in:

Dual-Specificity Protein Kinases

Other entries for this name:
alt prot [584aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [540aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [529aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
alt prot [763aa] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         45           2
 C cysteine            1.2          9           1
 D aspartate           4.8         36           3
 E glutamate           4.4         33           2
 F phenylalanine       3.2         24           2
 G glycine             7.0         53           2
 H histidine           6.2         47          13
 I isoleucine          3.7         28           2
 K lysine              5.3         40           3
 L leucine             7.0         53           2
 M methionine          3.1         23           1
 N asparagine          4.8         36           1
 P proline             5.2         39           2
 Q glutamine           6.8         51           2
 R arginine            5.3         40           2
 S serine              9.9         75           4
 T threonine           6.8         51           2
 V valine              4.9         37           2
 W tryptophan          0.7          5           1
 Y tyrosine            3.8         29           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   dual-specificity tyrosine-(Y)-phosphorylation regula... 
DYRK1A                0.995   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.715   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.657   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1A                0.653   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK1B                0.472   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK1B                0.431   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK1B                0.419   dual-specificity tyrosine-(Y)-phosphorylation regulat...
DYRK4                 0.169   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK3                 0.165   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK3                 0.165   dual-specificity tyrosine-(Y)-phosphorylation regula...
DYRK2                 0.165   dual-specificity tyrosine-(Y)-phosphorylation regul...
DYRK2                 0.165   dual-specificity tyrosine-(Y)-phosphorylation regulat...
HIPK2                 0.129   homeodomain interacting protein kinase 2 isoform 2 ...
HIPK2                 0.129   homeodomain interacting protein kinase 2 isoform 1 ...
HIPK1                 0.128   homeodomain-interacting protein kinase 1 isoform 1 [...
HIPK1                 0.128   homeodomain-interacting protein kinase 1 isoform 2 [...
HIPK3                 0.124   homeodomain interacting protein kinase 3 isoform 2 ...
HIPK3                 0.124   homeodomain interacting protein kinase 3 isoform 1 ...
HIPK4                 0.114   homeodomain interacting protein kinase 4 
CLK3                  0.099   CDC-like kinase 3 isoform a 
CLK3                  0.099   CDC-like kinase 3 isoform b 
CLK1                  0.096   CDC-like kinase 1 isoform 2 
CLK1                  0.096   CDC-like kinase 1 isoform 1 
CLK4                  0.096   CDC-like kinase 4 
CLK2                  0.095   CDC-like kinase 2 
PRPF4B                0.094   serine/threonine-protein kinase PRP4K 
LOC653052             0.073   PREDICTED: similar to homeodomain interacting prote...
CDKL5                 0.071   cyclin-dependent kinase-like 5 
CDKL5                 0.071   cyclin-dependent kinase-like 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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