Guide to the Human Genome
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Name: SYNGAP1 Sequence: fasta or formatted (1343aa) NCBI GI: 194248068
Description:

synaptic Ras GTPase activating protein 1

Referenced in:

Ras

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         87           2
 C cysteine            1.3         17           2
 D aspartate           3.9         53           2
 E glutamate           7.0         94           3
 F phenylalanine       3.0         40           1
 G glycine             8.6        116           7
 H histidine           3.4         45          10
 I isoleucine          3.6         48           2
 K lysine              4.8         65           2
 L leucine            10.3        139           2
 M methionine          2.9         39           2
 N asparagine          2.9         39           2
 P proline             8.1        109           6
 Q glutamine           4.5         61           3
 R arginine            7.7        104           2
 S serine             10.9        146           3
 T threonine           3.8         51           2
 V valine              3.6         48           2
 W tryptophan          0.7         10           1
 Y tyrosine            2.4         32           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   synaptic Ras GTPase activating protein 1 
DAB2IP                0.389   disabled homolog 2 interacting protein isoform 1 [Ho...
DAB2IP                0.369   disabled homolog 2 interacting protein isoform 2 [Ho...
RASAL2                0.368   RAS protein activator like 2 isoform 2 
RASAL2                0.350   RAS protein activator like 2 isoform 1 
RASAL3                0.143   RAS protein activator like 3 
RASA1                 0.046   RAS p21 protein activator 1 isoform 1 
RASA1                 0.046   RAS p21 protein activator 1 isoform 2 
RASA3                 0.037   RAS p21 protein activator 3 
LOC100132214          0.033   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.033   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.033   PREDICTED: similar to calcium-promoted Ras inactiva...
LOC100132214          0.033   PREDICTED: similar to calcium-promoted Ras inactiva...
RASA4                 0.033   RAS p21 protein activator 4 isoform 2 
RASA4                 0.033   RAS p21 protein activator 4 isoform 1 
RASA2                 0.032   RAS p21 protein activator 2 
RASAL1                0.031   RAS protein activator like 1 
NF1                   0.026   neurofibromin isoform 2 
NF1                   0.025   neurofibromin isoform 1 
LOC647042             0.014   PREDICTED: hypothetical protein isoform 1 
SHANK1                0.014   SH3 and multiple ankyrin repeat domains 1 
LOC100133220          0.013   PREDICTED: hypothetical protein 
YY1                   0.013   YY1 transcription factor 
ARID1B                0.012   AT rich interactive domain 1B (SWI1-like) isoform 2 ...
ARID1B                0.012   AT rich interactive domain 1B (SWI1-like) isoform 1 ...
ARID1B                0.012   AT rich interactive domain 1B (SWI1-like) isoform 3 ...
ATN1                  0.012   atrophin-1 
ATN1                  0.012   atrophin-1 
FUS                   0.012   fusion (involved in t(12;16) in malignant liposarcoma...
CACNA1A               0.011   calcium channel, alpha 1A subunit isoform 4 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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