Guide to the Human Genome
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Search of human proteins with 119508426

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119508426 alpha 3 type IX collagen [Homo sapiens]
         (684 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119508426 alpha 3 type IX collagen [Homo sapiens]                 1479   0.0  
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...   674   0.0  
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   673   0.0  
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   665   0.0  
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     546   e-155
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      544   e-154
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   538   e-153
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   536   e-152
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   535   e-152
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   535   e-152
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   535   e-152
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   534   e-152
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   534   e-152
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   534   e-152
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               532   e-151
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     532   e-151
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     527   e-149
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   526   e-149
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   521   e-148
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   521   e-148
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   521   e-148
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      519   e-147
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        516   e-146
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       513   e-145
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    511   e-144
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              510   e-144
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         505   e-143
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    504   e-142
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   493   e-139
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   493   e-139

>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 1479 bits (3828), Expect = 0.0
 Identities = 684/684 (100%), Positives = 684/684 (100%)

Query: 1   MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP 60
           MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP
Sbjct: 1   MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP 60

Query: 61  PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP 120
           PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP
Sbjct: 61  PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP 120

Query: 121 GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP 180
           GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP
Sbjct: 121 GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP 180

Query: 181 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240
           GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL
Sbjct: 181 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240

Query: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300
           GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP
Sbjct: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300

Query: 301 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA 360
           GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA
Sbjct: 301 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA 360

Query: 361 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420
           GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ
Sbjct: 361 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420

Query: 421 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480
           GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ
Sbjct: 421 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480

Query: 481 GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL 540
           GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL
Sbjct: 481 GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL 540

Query: 541 AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD 600
           AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD
Sbjct: 541 AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD 600

Query: 601 RGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
           RGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG
Sbjct: 601 RGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660

Query: 661 ICDTSACQGAVLGGVGEKSGSRSS 684
           ICDTSACQGAVLGGVGEKSGSRSS
Sbjct: 661 ICDTSACQGAVLGGVGEKSGSRSS 684


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score =  674 bits (1738), Expect = 0.0
 Identities = 333/658 (50%), Positives = 413/658 (62%), Gaps = 10/658 (1%)

Query: 13  LLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK 72
           LLLLG  L AA     G  GPPGPPGPPG PG DGIDG+ GP G PGPPGP G PGKPG 
Sbjct: 13  LLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 72

Query: 73  PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPP 132
           PG+   PG PG DGLTG DG PG  G+ G++G  G PG  G  G+G+PGPPG  G +G P
Sbjct: 73  PGK---PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLP 129

Query: 133 GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192
           G +G  GP G    PG  GPPGPPGPPG  G +     D  CP+ CPPG  G PG+PG +
Sbjct: 130 GELGRVGPVGD---PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMR 186

Query: 193 GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252
           G  G KGE GE G+ G KG+ G  G  G  G+ G  G +GLRG+ G +G  G++G  G  
Sbjct: 187 GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLD 246

Query: 253 GPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVP 312
           G PG  G PG  GD+G+RGP G  GPKGD G  G +G PG+ GP G+ G+PG DG++G+P
Sbjct: 247 GEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 306

Query: 313 GLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDA 372
           G+ G KGE G+ G PG+ G  GLPG+PG  G+KG  GE+G  G  G+ G  G  G PG  
Sbjct: 307 GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQ 366

Query: 373 GMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPG 432
           G PGE G  G +G  G+ G  GP G+PG+ G  G  GS G PGLPGP GL G  GDRG  
Sbjct: 367 GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVV 426

Query: 433 GAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP 492
           G  GPKG+QG +G +G  G++GELG  GL GPKG +G+ GE G +G +G  G  GV+G  
Sbjct: 427 GEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPR 486

Query: 493 GPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGS 552
           GPPGP G+QG  G  G+ G  G PG+  ++Q I+++C  +I E  A++AA L++P   G+
Sbjct: 487 GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP-DSGA 545

Query: 553 IGRPGPAGPPGPPGPPGSIGHP---GARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA 609
            G PG  GPPGPPGPPG  G P   G RG PG +GP G LG  GP+G+ G++G++G  G 
Sbjct: 546 TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR 605

Query: 610 GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSAC 667
           G +G  G  G  G  G     ++G+DG  G PG  G PG+PG  G  G PG C+ ++C
Sbjct: 606 GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 663



 Score =  343 bits (880), Expect = 3e-94
 Identities = 229/590 (38%), Positives = 269/590 (45%), Gaps = 134/590 (22%)

Query: 205 GKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA 264
           G  GE+G PGPPGP G+PG  G+ G R      GP GPPG  GP G  G PG PG PG  
Sbjct: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDR------GPKGPPGPPGPAGEPGKPGAPGKPGTP 79

Query: 265 GDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPG--MPGKDGQNGVPGLDGQKGEAG 322
           G  G  GP+G     G +G  G KG PGV G  G PG  +PG  G  G  GL G+ G  G
Sbjct: 80  GADGLTGPDG---SPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136

Query: 323 RNGAPGEKGPNGLPGLPGRAGSKG------------EKGERGRAGELGEAGPSGEPGVPG 370
             G PG +GP G PG PG  G+ G              G  G  G  G  G  G  G  G
Sbjct: 137 PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 196

Query: 371 DAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGF------QGQKGSMGDPGLPGPQGLRG 424
           + G  G +GE G +G  G +G QGPPGA G+RG       +G+KG+ G  G PGPQGL G
Sbjct: 197 EPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPG 256

Query: 425 ---DVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQG 481
              D G RGP G AGPKGD+G  G+ G+PG         L GPKG++G  G  G  G  G
Sbjct: 257 APGDQGQRGPPGEAGPKGDRGAEGARGIPG---------LPGPKGDTGLPGVDGRDGIPG 307

Query: 482 PNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELC----GGMISEQI 537
             GT G  G PGPPG  GLQG+PGVPGI G  GV G++ S     +       G   +Q 
Sbjct: 308 MPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQG 367

Query: 538 AQLAAHLRKPLA-PGSIGRPGPAGPPGPPGPPGSIGHPGARGPPG------YRGPTGELG 590
                  R P   PGS G  GP G PG PG  GS+G PG  G PG       +G  G +G
Sbjct: 368 PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG 427

Query: 591 DPGPRGNQGDRGDKGAAGA-------------------------------GLDGPEGDQG 619
           +PGP+G QG  G++G AG                                GL G EG +G
Sbjct: 428 EPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG 487

Query: 620 PQGPQGV----------------------------------------------PGTSKDG 633
           P GP+GV                                              P +   G
Sbjct: 488 PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 547

Query: 634 QDGAPGEPGPPGDP---GLPGAIGAQGTPGICDTSACQG--AVLGGVGEK 678
             G PG PGPPG P   G PG +G +G PGI       G     G +GEK
Sbjct: 548 LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK 597



 Score =  259 bits (663), Expect = 4e-69
 Identities = 174/423 (41%), Positives = 193/423 (45%), Gaps = 123/423 (29%)

Query: 22  AAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGL 81
           A GA+  G+PG PGP G  G PG DG DG      +PG PG KG PGKPG PG+AGL GL
Sbjct: 278 AEGAR--GIPGLPGPKGDTGLPGVDGRDG------IPGMPGTKGEPGKPGPPGDAGLQGL 329

Query: 82  PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPG---PPGEAGVSGPPGGIGL 137
           PGV G+      PG KG  GE+GS G PG PG +G  G PG   PPGE G  GP G  G 
Sbjct: 330 PGVPGI------PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS 383

Query: 138 RGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGM--------- 188
           RG  GP G PGLPG  G  G PG PG+               PGPPG PGM         
Sbjct: 384 RGELGPVGSPGLPGKLGSLGSPGLPGL---------------PGPPGLPGMKGDRGVVGE 428

Query: 189 PGFKGPTGYKGEQGEVGKDGEKGD---------------------------PGPPGPAGL 221
           PG KG  G  GE+GE G+ GE GD                           PG  GP G 
Sbjct: 429 PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGP 488

Query: 222 PGSVGLQGPRGLRGLPGPLGPPG------------------------------DRGPIGF 251
           PG  G+QG +G  GLPG  GPPG                              D G  G 
Sbjct: 489 PGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGL 548

Query: 252 RGPPGIPGAPGKAGD---------------RGERGPEGFRGPKGDLGRPGPKGTPGVAGP 296
            G PG PG PG  G+               +G  G  G RGPKGDLG  G +G PG  GP
Sbjct: 549 PGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGP 607

Query: 297 SGEPGM--------PGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEK 348
           +G PG         P   G+NG  G  G  G AG  G PG  GP GLPG    A    + 
Sbjct: 608 NGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQA 667

Query: 349 GER 351
           G+R
Sbjct: 668 GQR 670



 Score =  235 bits (599), Expect = 1e-61
 Identities = 155/378 (41%), Positives = 173/378 (45%), Gaps = 95/378 (25%)

Query: 27  RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK------PGKPGEAGLPG 80
           R G+PG PG  G PGKPG  G  G  G PG+PG PG KG  G+      PGKPG+ G  G
Sbjct: 302 RDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 361

Query: 81  LPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK----------GLPGPPGEAGVSG 130
            PG  G  G  GP GP+G PG RG LGP G PGL GK          GLPGPPG  G+ G
Sbjct: 362 KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 421

Query: 131 PPGGIGLRGPPGPSGLPG---------------LPGPPGPPGPPGHPGVL-PEGATDLQC 174
             G +G  GP G  G  G               LPGP G  G PG PG+  PEG+  L  
Sbjct: 422 DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL-- 479

Query: 175 PSI-CPPGPPGPPGMPGFKGPTGYKGEQGEVGK--------------------------- 206
           P +  P GPPGP G+ G +G TG  G QG  G+                           
Sbjct: 480 PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 539

Query: 207 ------DGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG---------------D 245
                  G  G PGPPGP G PG  G  G  G+RGLPG  GPPG               +
Sbjct: 540 RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 599

Query: 246 RGPIGFRGPPGIPGAPGKAGDRG-----------ERGPEGFRGPKGDLGRPGPKGTPGVA 294
           RGP G RGP G+PGA G  GD G           ERGP G  G  G  G PGP G PG  
Sbjct: 600 RGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 658

Query: 295 GPSGEPGMPGKDGQNGVP 312
            P+      G+   N  P
Sbjct: 659 EPASCTMQAGQRAFNKGP 676



 Score =  214 bits (545), Expect = 2e-55
 Identities = 141/373 (37%), Positives = 171/373 (45%), Gaps = 89/373 (23%)

Query: 350 ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKG 409
           +RG  GE G  GP G PGVPG  G+ G+RG            P+GPPG PG  G  G+ G
Sbjct: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRG------------PKGPPGPPGPAGEPGKPG 71

Query: 410 SMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESG 469
           + G PG PG  GL G  G  G  G+ G KG+ G+ GS G PG        G+ GP G  G
Sbjct: 72  APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-------RGIPGPPGPPG 124

Query: 470 SRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGV------------PGITGKPGVPG 517
           + G  G  G  GP G  G +G PGPPGP G +G  G             PG +G PG+PG
Sbjct: 125 TAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPG 184

Query: 518 KEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGAR 577
               +                          A G IG PG  G  G  G  G +G  GA+
Sbjct: 185 MRGHKG-------------------------AKGEIGEPGRQGHKGEEGDQGELGEVGAQ 219

Query: 578 GPPG---YRGPTGELGD------------PGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQ 621
           GPPG    RG TG +GD            PGP+G  G  GD+G  G  G  GP+GD+G +
Sbjct: 220 GPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAE 279

Query: 622 GPQGVPGT----------SKDGQDGAPGEPGP---PGDPGLPGAIGAQGTPGICDTSACQ 668
           G +G+PG             DG+DG PG PG    PG PG PG  G QG PG+      +
Sbjct: 280 GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAK 339

Query: 669 GAVLGGVGEKSGS 681
           G      GEK  +
Sbjct: 340 GV----AGEKGST 348



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 55/131 (41%), Positives = 63/131 (48%), Gaps = 4/131 (3%)

Query: 531 GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELG 590
           G++   +   AA    P   G  G PGP G PG  G  G     G +GPPG  GP GE G
Sbjct: 12  GLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGD---RGPKGPPGPPGPAGEPG 68

Query: 591 DPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGL 649
            PG  G  G  G  G  G  G  G  G +G +G  GVPG+      G PG PGPPG  GL
Sbjct: 69  KPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL 128

Query: 650 PGAIGAQGTPG 660
           PG +G  G  G
Sbjct: 129 PGELGRVGPVG 139



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 48/129 (37%), Positives = 53/129 (41%), Gaps = 46/129 (35%)

Query: 29  GLPGPPGPPGPPGK---PGQDGI------------------------DGEAGPPG----- 56
           G PGPPGPPGPPG+   PGQ GI                         GE GPPG     
Sbjct: 550 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNG 609

Query: 57  ------LPGPPGP-----KGAPGKPGKPGEAGLPGLP---GVDGLTGRDGPPGPKGAPGE 102
                 LPG PGP      G  G+ G PG AG+PG+P   G  GL G   P       G+
Sbjct: 610 LPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQ 669

Query: 103 RGSLGPPGP 111
           R     P P
Sbjct: 670 RAFNKGPDP 678



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 35/92 (38%), Positives = 40/92 (43%), Gaps = 14/92 (15%)

Query: 600 DRGDKGAAGAGLDGPEGDQGPQGPQGVPG-------------TSKDGQDGAPGEPGPPGD 646
           DRG  G    GL      +GP G QG PG                 G  G PG PGP G+
Sbjct: 7   DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE 66

Query: 647 PGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678
           PG PGA G  GTPG    +   G+  G +G K
Sbjct: 67  PGKPGAPGKPGTPGADGLTGPDGSP-GSIGSK 97


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  673 bits (1736), Expect = 0.0
 Identities = 341/668 (51%), Positives = 408/668 (61%), Gaps = 16/668 (2%)

Query: 13  LLLLGELLAAAGAQRVGLPG---PPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK 69
           LL+L +++  A AQ  G PG   PPGPPGPPG PG DGIDG+ GPPG  GPPGPKG PGK
Sbjct: 11  LLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGK 70

Query: 70  PGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVS 129
            G  G     G PG+DGLTG  G PGP G PG +G  G PGPPGL G G  GPPG  G  
Sbjct: 71  AGPDGP---DGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPV 127

Query: 130 GPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLP--EGATDLQCPSICPPGPPGPPG 187
           G PG IG+RGP G  G  G  GPPGPPG PG PG +   EG+ D  CP+ CPPG  GPPG
Sbjct: 128 GLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPG 187

Query: 188 MPGFKGPTGYKG---EQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG 244
           + G KG  G +G   + G  GK G KGD G  G  G+PG     GP+G+RG PG  GP G
Sbjct: 188 LQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP---PGPQGIRGYPGMAGPKG 244

Query: 245 DRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPG 304
           + GP G++G  G  GA G  G+ G RGP G  G KGD G PG +G  G+ GP G  G PG
Sbjct: 245 ETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPG 304

Query: 305 KDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSG 364
            +G++G PG  G KG AG+ G PG  G  GL G+PG+ G+KG  G++G  G  G  G SG
Sbjct: 305 INGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSG 364

Query: 365 EPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG 424
            PG  G+ G  GE G  G  G  G  G +GP G PG +G QG KG  G PG+PGPQGL G
Sbjct: 365 PPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPG 424

Query: 425 DVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNG 484
             GD+G  G  GP+G  G  G  GLPG+KGE G SG  GPKG+ G RGE G  G  G  G
Sbjct: 425 VKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAG 484

Query: 485 TSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHL 544
             GVQG PGPPGP GL G  GVPG  G+ GV G++A++Q I ++   M+ EQ+A++A   
Sbjct: 485 APGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSA 544

Query: 545 RKPL--APGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRG 602
           ++    A G +G PGP GPPG PG  G  GHPG RG PG  G  G++G+ GP+G +G++G
Sbjct: 545 KREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKG 604

Query: 603 DKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662
           D G  G G  G  G  G  G  G PG + +G+DG  G PG PG+ G PG  G  G PG C
Sbjct: 605 DPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFC 664

Query: 663 DTSACQGA 670
           + +AC GA
Sbjct: 665 EPAACLGA 672



 Score =  417 bits (1073), Expect = e-116
 Identities = 256/630 (40%), Positives = 296/630 (46%), Gaps = 106/630 (16%)

Query: 97  KGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPP 156
           +G PGERG  GPPGPPG+     PG  G  G +GPPG  G   PPGP G PG     GP 
Sbjct: 26  RGPPGERGPPGPPGPPGV-----PGSDGIDGDNGPPGKAG---PPGPKGEPG---KAGPD 74

Query: 157 GPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPP 216
           GP G PG+  +G T  +       G PGP G+PG KG  G  G  G  G  G  G PGPP
Sbjct: 75  GPDGKPGI--DGLTGAK-------GEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPP 124

Query: 217 GPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRG-----------------PPGIPG 259
           GP GLPG +G++GP+G  G  GP GPPG  G  G  G                 PPG+ G
Sbjct: 125 GPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKG 184

Query: 260 APGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKG 319
            PG  G +G  G  G  G  G  G+PGPKG  G +G  G PG PG  G  G PG+ G KG
Sbjct: 185 PPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKG 244

Query: 320 EAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERG 379
           E G +G  G  G  G  G PG      E+G RG  G  GE G  G PG+ G  G+ G +G
Sbjct: 245 ETGPHGYKGMVGAIGATGPPG------EEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKG 298

Query: 380 EAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPG------LPGPQGLRGDVGDRGPGG 433
             G     G  G  G PG PG++G  GQ G  G PG      +PG  G +G  GD+G  G
Sbjct: 299 ATG---PPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPG 355

Query: 434 AAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPG 493
             G  G  G  G +G PG +GE+GP G++G KG+ G RG +G  G QG  G  G QG PG
Sbjct: 356 PQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPG 415

Query: 494 PPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSI 553
            PGP GL GV G  G  GK G  GK                               PG  
Sbjct: 416 IPGPQGLPGVKGDKGSPGKTGPRGKVGD----------------------------PGVA 447

Query: 554 GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLD 612
           G PG  G  G  G PG  G  G RG PGY GP+G+ G PG +G  G  G +G AG  G+ 
Sbjct: 448 GLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVP 507

Query: 613 GPEGDQGPQGPQGVPGTSKD----------------------GQDGAPGEPGPPGDPGLP 650
           G  G QG +G         D                      G  G  G PGPPG PG P
Sbjct: 508 GQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYP 567

Query: 651 GAIGAQGTPGICDTSACQGAV--LGGVGEK 678
           G  G  G PG        GAV  +G  G K
Sbjct: 568 GKQGPHGHPGPRGVPGIVGAVGQIGNTGPK 597



 Score =  266 bits (681), Expect = 4e-71
 Identities = 180/466 (38%), Positives = 211/466 (45%), Gaps = 103/466 (22%)

Query: 20  LAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPG---------PPGPKGAPGKP 70
           + A+G Q  G+PGPPGP G  G PG  G  GE GP G  G         PPG +G  G P
Sbjct: 216 VGASGEQ--GIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273

Query: 71  GKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK----GLPGPPGEA 126
           G+ GE G  G PG+ G  G  GP G  G PG  G  G PG PG+ G     G PG PG  
Sbjct: 274 GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQ 333

Query: 127 GVSGPPG------GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPS--- 176
           G++G PG      G G +G PGP GLPG  GPPG  G PG  G + P+G    +      
Sbjct: 334 GLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGER 393

Query: 177 --ICPPGPPG---------PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSV 225
             +  PGP G         PPG+PG +G  G KG++G  GK G +G  G PG AGLPG  
Sbjct: 394 GPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEK 453

Query: 226 GLQGP---------RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFR 276
           G +G          +G+RG PG  GP GD G  G +G PG PG  G AG+RG  G  G +
Sbjct: 454 GEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQ 513

Query: 277 GPKGD------------------------------------LGRPGPKGTPGVAGPSGEP 300
           G +G                                     +G PGP G PG  G  G  
Sbjct: 514 GVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPH 573

Query: 301 GMPGKDGQNGVPGLDGQ------KGEAGRNGAPGE--------KGPNGLPGLPGRAGS-- 344
           G PG  G  G+ G  GQ      KG+ G  G PGE         GP G+PGLPGR G   
Sbjct: 574 GHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAI 633

Query: 345 ------KGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHR 384
                 +G  G  G AG  G  GP G PG    A   G    A  R
Sbjct: 634 NGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASAR 679


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score =  665 bits (1717), Expect = 0.0
 Identities = 325/642 (50%), Positives = 405/642 (63%), Gaps = 10/642 (1%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
           G  GPPGPPGPPG PG DGIDG+ GP G PGPPGP G PGKPG PG+   PG PG DGLT
Sbjct: 272 GEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK---PGTPGADGLT 328

Query: 89  GRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPG 148
           G DG PG  G+ G++G  G PG  G  G+G+PGPPG  G +G PG +G  GP G    PG
Sbjct: 329 GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGD---PG 385

Query: 149 LPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDG 208
             GPPGPPGPPG  G +     D  CP+ CPPG  G PG+PG +G  G KGE GE G+ G
Sbjct: 386 RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG 445

Query: 209 EKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRG 268
            KG+ G  G  G  G+ G  G +GLRG+ G +G  G++G  G  G PG  G PG  GD+G
Sbjct: 446 HKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQG 505

Query: 269 ERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPG 328
           +RGP G  GPKGD G  G +G PG+ GP G+ G+PG DG++G+PG+ G KGE G+ G PG
Sbjct: 506 QRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPG 565

Query: 329 EKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAG 388
           + G  GLPG+PG  G+KG  GE+G  G  G+ G  G  G PG  G PGE G  G +G  G
Sbjct: 566 DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPG 625

Query: 389 ALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDG 448
           + G  GP G+PG+ G  G  GS G PGLPGP GL G  GDRG  G  GPKG+QG +G +G
Sbjct: 626 SRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEG 685

Query: 449 LPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPG 508
             G++GELG  GL GPKG +G+ GE G +G +G  G  GV+G  GPPGP G+QG  G  G
Sbjct: 686 EAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATG 745

Query: 509 ITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPP 568
           + G  G PG+  ++Q I+++C  +I E  A++AA L++P   G+ G PG  GPPGPPGPP
Sbjct: 746 LPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP-DSGATGLPGRPGPPGPPGPP 804

Query: 569 GSIGHP---GARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQG 625
           G  G P   G RG PG +GP G LG  GP+G+ G++G++G  G G +G  G  G  G  G
Sbjct: 805 GENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG 864

Query: 626 VPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSAC 667
                ++G+DG  G PG  G PG+PG  G  G PG C+ ++C
Sbjct: 865 PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906



 Score =  350 bits (898), Expect = 2e-96
 Identities = 238/616 (38%), Positives = 274/616 (44%), Gaps = 138/616 (22%)

Query: 157 GPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGP- 215
           GPPG  G               PPGPPGPPG+PG                DG  GD GP 
Sbjct: 269 GPPGEQG---------------PPGPPGPPGVPGI---------------DGIDGDRGPK 298

Query: 216 -----PGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGE- 269
                PGPAG PG  G  G  G  G  G  GP G  G IG +G  G PG PG  G  G  
Sbjct: 299 GPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRG 358

Query: 270 ----RGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPG---------------------MPG 304
                GP G  G  G+LGR GP G PG  GP G PG                      PG
Sbjct: 359 IPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPG 418

Query: 305 KDGQNGVPGLDGQKGEAGRNGAPGE------------------KGPNGLPGLPGRAGSKG 346
           + G  G+PG+ G KG  G  G PG                   +GP G  GL G  G  G
Sbjct: 419 RSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVG 478

Query: 347 EKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQG 406
           +KGE+G  G  GE GP G PG PGD G  G  GEAG +G  GA G +G PG PG +G  G
Sbjct: 479 DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTG 538

Query: 407 QKGSMGDPGLPGPQGLRGDVGDRGPGGAA------------GPKGDQGIAGSDGLPGDKG 454
             G  G  G+PG  G +G+ G  GP G A            G KG  G  GS G PG  G
Sbjct: 539 LPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG 598

Query: 455 ELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPG 514
           ++G SG  G +G  G  G  GP+G  G  G  G  G PG PG LG  G PG+PG+ G PG
Sbjct: 599 QMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG 658

Query: 515 VPGKEASEQRIRELCGGMISEQIA---QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSI 571
           +PG +     + E   G   EQ A   +  A  R  L  G IG PGP G  G PG PG  
Sbjct: 659 LPGMKGDRGVVGE--PGPKGEQGASGEEGEAGERGEL--GDIGLPGPKGSAGNPGEPGLR 714

Query: 572 GHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEG--------------- 616
           G  G+RG PG  GP    G PGPRG QG++G  G    G+ GP G               
Sbjct: 715 GPEGSRGLPGVEGPR---GPPGPRGVQGEQGATGL--PGVQGPPGRAPTDQHIKQVCMRV 769

Query: 617 ------------DQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDT 664
                        +   G  G+P     G+ G PG PGPPG+ G PG +G +G PGI   
Sbjct: 770 IQEHFAEMAASLKRPDSGATGLP-----GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 824

Query: 665 SACQG--AVLGGVGEK 678
               G     G +GEK
Sbjct: 825 PGALGLRGPKGDLGEK 840



 Score =  299 bits (766), Expect = 5e-81
 Identities = 202/479 (42%), Positives = 229/479 (47%), Gaps = 86/479 (17%)

Query: 16  LGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK--- 72
           LGE+ A       GL G  G  G  G+ G  G+DGE GP GLPG PG +G  G PG+   
Sbjct: 456 LGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGP 515

Query: 73  ------PGEAGLPGLP------GVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGG-KGL 119
                  G  G+PGLP      G+ G+ GRDG PG  G  GE G  GPPG  GL G  G+
Sbjct: 516 KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGV 575

Query: 120 PGPPGEAGVSGPPGGIGLRGPPGP---SGLPGLPGPP---GPPGPPGHPGV--------- 164
           PG PG  GV+G  G  G  G PG    SG PG  GPP   GP GP G PG          
Sbjct: 576 PGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGS 635

Query: 165 --LPEGATDLQCPSICPPGPPGPPGMPGFKGPTGY------KGEQGEVGKDGEKGD---- 212
             LP     L  P +  PG PGPPG+PG KG  G       KGEQG  G++GE G+    
Sbjct: 636 PGLPGKLGSLGSPGL--PGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL 693

Query: 213 -----PGPPGPAGLPGSVGLQGPRGLRGLP---GPLGPPGDRGPIGFRGPPGIPGAPGKA 264
                PGP G AG PG  GL+GP G RGLP   GP GPPG RG  G +G  G+PG  G  
Sbjct: 694 GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPP 753

Query: 265 GDRGERGP--------------EGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNG 310
           G    R P              E F      L RP   G  G+ G  G PG PG  G+NG
Sbjct: 754 G----RAPTDQHIKQVCMRVIQEHFAEMAASLKRP-DSGATGLPGRPGPPGPPGPPGENG 808

Query: 311 VPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPG 370
            P      G+ G  G PG KGP G  GL G  G  GEKGERG  G        G  G+PG
Sbjct: 809 FP------GQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-------GPNGLPG 855

Query: 371 DAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDR 429
             G+PG+ G A + G  G  G +GPPG  G+ G  G  G  G PG   P       G R
Sbjct: 856 AIGLPGDPGPASY-GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913



 Score =  248 bits (634), Expect = 1e-65
 Identities = 164/419 (39%), Positives = 201/419 (47%), Gaps = 67/419 (15%)

Query: 299 EPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG 358
           +P  P ++  + +P            G PGE+GP G PG PG  G  G  G+RG  G  G
Sbjct: 243 DPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPG 302

Query: 359 EAGPSGEPGVPGDAGMPGE------RGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMG 412
             GP+GEPG PG  G PG        G  G  GS G+ G +G PG PG RGF G +G  G
Sbjct: 303 PPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPG 361

Query: 413 DPGLPGPQGLR---------GDVGDRGPGGAAGPKGDQGI------------------AG 445
            PG PG  GL          GD G RGP G  GP G +G                   +G
Sbjct: 362 PPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSG 421

Query: 446 SDGLP------GDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP---GPPG 496
             GLP      G KGE+G  G  G KGE G +GELG  G QGP G  G++G+    G  G
Sbjct: 422 YPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKG 481

Query: 497 PLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHL-RKPLAPGSIGR 555
             G +G+ G PG  G PG PG +       E   G   ++ A+ A  +   P   G  G 
Sbjct: 482 EKGARGLDGEPGPQGLPGAPGDQGQRGPPGE--AGPKGDRGAEGARGIPGLPGPKGDTGL 539

Query: 556 PGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA------ 609
           PG  G  G PG PG+ G PG  GPPG  G  G  G PG  G +G  G+KG+ GA      
Sbjct: 540 PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 599

Query: 610 -------GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
                  G  GP G+ GP+GPQG+PG+         GE GP G PGLPG +G+ G+PG+
Sbjct: 600 MGNSGKPGQQGPPGEVGPRGPQGLPGSR--------GELGPVGSPGLPGKLGSLGSPGL 650



 Score =  235 bits (599), Expect = 1e-61
 Identities = 155/378 (41%), Positives = 173/378 (45%), Gaps = 95/378 (25%)

Query: 27  RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK------PGKPGEAGLPG 80
           R G+PG PG  G PGKPG  G  G  G PG+PG PG KG  G+      PGKPG+ G  G
Sbjct: 545 RDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 604

Query: 81  LPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK----------GLPGPPGEAGVSG 130
            PG  G  G  GP GP+G PG RG LGP G PGL GK          GLPGPPG  G+ G
Sbjct: 605 KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 664

Query: 131 PPGGIGLRGPPGPSGLPG---------------LPGPPGPPGPPGHPGVL-PEGATDLQC 174
             G +G  GP G  G  G               LPGP G  G PG PG+  PEG+  L  
Sbjct: 665 DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL-- 722

Query: 175 PSI-CPPGPPGPPGMPGFKGPTGYKGEQGEVGK--------------------------- 206
           P +  P GPPGP G+ G +G TG  G QG  G+                           
Sbjct: 723 PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 782

Query: 207 ------DGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG---------------D 245
                  G  G PGPPGP G PG  G  G  G+RGLPG  GPPG               +
Sbjct: 783 RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842

Query: 246 RGPIGFRGPPGIPGAPGKAGDRG-----------ERGPEGFRGPKGDLGRPGPKGTPGVA 294
           RGP G RGP G+PGA G  GD G           ERGP G  G  G  G PGP G PG  
Sbjct: 843 RGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 901

Query: 295 GPSGEPGMPGKDGQNGVP 312
            P+      G+   N  P
Sbjct: 902 EPASCTMQAGQRAFNKGP 919



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 48/129 (37%), Positives = 53/129 (41%), Gaps = 46/129 (35%)

Query: 29  GLPGPPGPPGPPGK---PGQDGI------------------------DGEAGPPG----- 56
           G PGPPGPPGPPG+   PGQ GI                         GE GPPG     
Sbjct: 793 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNG 852

Query: 57  ------LPGPPGP-----KGAPGKPGKPGEAGLPGLP---GVDGLTGRDGPPGPKGAPGE 102
                 LPG PGP      G  G+ G PG AG+PG+P   G  GL G   P       G+
Sbjct: 853 LPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQ 912

Query: 103 RGSLGPPGP 111
           R     P P
Sbjct: 913 RAFNKGPDP 921


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  546 bits (1407), Expect = e-155
 Identities = 311/695 (44%), Positives = 359/695 (51%), Gaps = 60/695 (8%)

Query: 27   RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGL---PG 83
            R G  GP GP GPPG  GQ+G  G  G  G PG PG  GAPG  G PG  G PGL   PG
Sbjct: 369  RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPG 428

Query: 84   VDG------LTGRDGPPGPKGAPGERGSLGPPGPPGLG---------GKGLPGPPGEAGV 128
             DG        G +G PGP G  G+ G+ G PGPPG G           GLPGP G  G 
Sbjct: 429  KDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGD 488

Query: 129  SGPPG-----------GIGLRGPPGPSG------------LPGLPGPPGPPGPPGHPGVL 165
             G PG           GIG+ GPPGPSG            LPG PGP GP G  G   +L
Sbjct: 489  RGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLL 548

Query: 166  PEGATDLQCPSI---CPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLP 222
              G  +L    +   CPPGPPG PG+PGFKG  G  G+ G  G +G+KG+ GPPG  G P
Sbjct: 549  SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP 608

Query: 223  GSVGLQGPRGLRGLPGPLGPPGDR---GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPK 279
            G  G QG +G RG  G +G  GD+   G  GF GPPG PG PG  G  G  GP G +   
Sbjct: 609  GIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ--- 665

Query: 280  GDLGRPGPKGTPGVAGPSGEPGMP---GKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLP 336
               G PG +G PG  GPSG PG+P   GK+G++G PG  G+ G+AG  G PG +G  G P
Sbjct: 666  ---GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPP 722

Query: 337  GLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPP 396
            G  G  G  G  G RG +G +G  G  G PG  GD G  G +G  G RG  G  G  G P
Sbjct: 723  GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 782

Query: 397  GAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL 456
            G PG  G  GQKGS G+ G PG  G  G  G  G  G  G  G +G+ G  G PG KGE 
Sbjct: 783  GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGER 842

Query: 457  GPSGLVGPKGESGSRGELGPKGTQGPNGTSGV---QGVPGPPGPLGLQGVPGVPGITGKP 513
            G  G+ G KG  G +G+ G  G  G  G +G+   QG+PG  GP+G  G PG PG  G  
Sbjct: 843  GDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLR 902

Query: 514  G-VPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG 572
            G  P  E   + I+E  G  +  ++A L A +       S GRPGP GPPG  G PG  G
Sbjct: 903  GESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAG 962

Query: 573  HPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKD 632
              G  G PG  G  G  G  GP+G +G +GD GA G GL G  G  G  G  G PG +KD
Sbjct: 963  PMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD 1022

Query: 633  GQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSAC 667
            G  G PG  G  G  G PG  G  G PG CD S C
Sbjct: 1023 GLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQC 1057



 Score =  505 bits (1301), Expect = e-143
 Identities = 299/689 (43%), Positives = 348/689 (50%), Gaps = 97/689 (14%)

Query: 30  LPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTG 89
           L G PG  G  G PG+ G+ GE G  GL G PG KG  G PG PG  G+ G  G  G  G
Sbjct: 248 LNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 307

Query: 90  RDGPPGPKGAPGERGSLGPPGPPGL--------------------GGKGLPGPPGEAGVS 129
             G PG KG  GE+G  GP GPPGL                    G KG PG PGE G+ 
Sbjct: 308 ELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQ 367

Query: 130 GPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMP 189
           G PG +G +GP GP G  G  G  G PG  G+PG        +  P   P GPPG  G P
Sbjct: 368 GRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG----APGHVGAPG--PSGPPGSVGAP 421

Query: 190 GFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP--RGLRGLPGPLGPPGDRG 247
           G +G  G  GE+GE G  GE+G PGP GP G PG+ GL GP  +G  G PG  G PG  G
Sbjct: 422 GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 481

Query: 248 PIGF---RGPPGIPGAPGKAGDR--GERGPEGFRGPKGDLGRPGPKGTPGVAGPS----- 297
           P+G    RG PGIPG+PG  GD   G  GP G  GP GD G PG +G PG  GP      
Sbjct: 482 PLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 541

Query: 298 -------------------------GEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGP 332
                                    G PG+PG  G  G  G+ G+ G  G  G  GE GP
Sbjct: 542 DGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGP 601

Query: 333 NGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGP 392
            GLPG PG AG +G +GERG  GE+G+ G  G PGVPG  G PG  G  G  G AGA GP
Sbjct: 602 PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGP 661

Query: 393 QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGL--- 449
            G  G+PG  G  G +G  G PG+PG +G  G  G  GP G  G  G+ G+ G +G    
Sbjct: 662 PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGP 721

Query: 450 PGDKGELGPSGLVGPKGESGSR---GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGV 506
           PG KG  G SG  GP+GESG+    G+ G  G  G  G +G QG  GP GP G  G PG 
Sbjct: 722 PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS 781

Query: 507 PGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPG 566
           PG  G  G PG++ S+                        P  PG +G  GP G PG  G
Sbjct: 782 PGEPGPSGTPGQKGSK-------------------GENGSPGLPGFLGPRGPPGEPGEKG 822

Query: 567 PPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQG 625
            PG  G PG  G PG++   GE GDPG +G++G  G KG  G  G+ G +G  G  GPQG
Sbjct: 823 VPGKEGVPGKPGEPGFK---GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQG 879

Query: 626 VPGTSKDGQDGAPGEPGPPGDPGLPGAIG 654
           +P     G++G  G PGPPG PG PG  G
Sbjct: 880 LP-----GENGPVGPPGPPGQPGFPGLRG 903



 Score =  447 bits (1149), Expect = e-125
 Identities = 273/635 (42%), Positives = 313/635 (49%), Gaps = 106/635 (16%)

Query: 61  PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP 120
           PG K   G+PG+ GE GLPG PG   L G  G  G  G PGE+G  G PG PG      P
Sbjct: 243 PGLKQLNGEPGERGEDGLPGKPG---LRGEIGEQGLAGRPGEKGEAGLPGAPGF-----P 294

Query: 121 GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP 180
           G  GE G  G  G +GL G  G  G  G  GP GPPG PG         T L  P    P
Sbjct: 295 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG--------TTSLFTPHPRMP 346

Query: 181 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240
           G  GP G  G  G  G  G QG  G+ G +G  GPPG  G  G+ G  G  G  G PG +
Sbjct: 347 GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV 406

Query: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300
           G PG  GP G  G PG+ G PGK G+RGE+G  G  G  G +G  G  G PG+ GP G+ 
Sbjct: 407 GAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK- 465

Query: 301 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA 360
              GKDG+   PGL   +G  G  G  G KG  G PG+PG  GS+G+ G       +G A
Sbjct: 466 ---GKDGE---PGL---RGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPG-------IGVA 509

Query: 361 GPSGEPGVPGDAGMPGERGEAGHRGSAGALG------------------------PQGPP 396
           GP G  G PGD G PG RG  G  G  G  G                        P GPP
Sbjct: 510 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPP 569

Query: 397 GAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGD---RGPGGAAGPKGDQGIAGSD---GLP 450
           G PG+ GF+G KG  G PG  G +G +G+ G     GP G AGP+G QG  G+D   G  
Sbjct: 570 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK 629

Query: 451 GDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGIT 510
           GD+G  G  G +GP G  G  G  G  G  GP G  G  G  GPPGP G  G+PG+PG  
Sbjct: 630 GDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEE 689

Query: 511 GKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGS 570
           GK G  GK                               PG  G PG AG PG PGP   
Sbjct: 690 GKEGRDGK-------------------------------PGPPGEPGKAGEPGLPGP--- 715

Query: 571 IGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA----GLDGPEGDQGPQGPQGV 626
               GARGPPG++G TG+ G PGPRG  G  G  G  G     G  GP G QGPQGP+G 
Sbjct: 716 ---EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP 772

Query: 627 PGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
           PG  K+G  G+PGEPGP G PG  G+ G  G+PG+
Sbjct: 773 PG--KNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 805



 Score =  405 bits (1041), Expect = e-113
 Identities = 245/597 (41%), Positives = 277/597 (46%), Gaps = 117/597 (19%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGL--PGPPGPKGAPGKPGKPGEAGLPGLPGVDG 86
            GLPGP G  G  G PG  G  G  G PG+   GPPGP G PG  G PG  GLPG PG  G
Sbjct: 478  GLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 537

Query: 87   LTGRDG------------------------PPGPKGAPGERGSLGPPGPPG--------- 113
              GRDG                        PPG  G PG +G  G PG PG         
Sbjct: 538  PAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 597

Query: 114  -LGGKGLPGPPGEAGVSGPPGG------IGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLP 166
              G  GLPGPPG AG  G  G       +G +G  G  G+PG  GPPG PGPPG  G+  
Sbjct: 598  EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 657

Query: 167  EGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVG 226
                    P I   G PG  G PG +GP+G  G  GE GK+G  G PGPPG  G  G  G
Sbjct: 658  AAGP----PGI--QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 711

Query: 227  LQGPRGLRGLPG------PLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKG 280
            L GP G RG PG        G PG RG  G  G PG  G PGK GD G  GP+G +GP+G
Sbjct: 712  LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRG 771

Query: 281  DLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPG 340
              G+ G  G+PG  GPSG PG  G  G+NG PGL G  G  G  G PGEKG  G  G+PG
Sbjct: 772  PPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG 831

Query: 341  RAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA------LGPQG 394
            + G  G KGERG  G  G+ GP G  G PGD G+PG +G  G  G  G       +GP G
Sbjct: 832  KPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 891

Query: 395  PPGAPGVRGFQGQKGSM--------------------------------------GDPGL 416
            PPG PG  G +G+  SM                                      G PG 
Sbjct: 892  PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 951

Query: 417  PGPQGLRGDVGD------------RGPGGAAGPKGDQGIAGSDGLPGD--KGELGPSGLV 462
            PG  GL G  G              GP G  GPKG++G  G  G PG   +GE+GP G+ 
Sbjct: 952  PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIP 1011

Query: 463  GPKGESGSR-----GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPG 514
            G  GE G       G  GP+G  GP G  G+ G PGPPG            +  +PG
Sbjct: 1012 GQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1068



 Score =  330 bits (846), Expect = 3e-90
 Identities = 211/511 (41%), Positives = 239/511 (46%), Gaps = 101/511 (19%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDG---EAGPPGLPGPPG---------------------PK 64
            GLPG  G  G PGKPG++G +G   EAGPPGLPGPPG                      +
Sbjct: 573  GLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ 632

Query: 65   GAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124
            G PG PG  G  G PG PG DG+ G  GPPG +G+PG+ G  GP GP      GLPG PG
Sbjct: 633  GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGP-----SGLPGIPG 687

Query: 125  EAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPG---HPGVLPEGATDLQCPSICPPG 181
            E G  G  G  G  G PG +G PGLPGP G  GPPG   H G         +  ++  PG
Sbjct: 688  EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG 747

Query: 182  PPGPPGMPGFKGPTGYKGEQGE---VGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPG 238
              G PG  G  GPTG +G QG     GK+G  G PG PGP+G PG  G +G  G  GLPG
Sbjct: 748  QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 807

Query: 239  ---PLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKG---------DLGRPG 286
               P GPPG+ G  G  G  G+PG PG+ G +GERG  G +G KG         D G PG
Sbjct: 808  FLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG 867

Query: 287  PKGTPGVAGPSGEPGM------PGKDGQNGVPGLDGQ----------------------- 317
             KG  G+ GP G PG       PG  GQ G PGL G+                       
Sbjct: 868  HKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRL 927

Query: 318  ------------KGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGE 365
                        K   GR G PG  G +GLPG  G  G  G  G+ G  G  G  GP GE
Sbjct: 928  AYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGE 987

Query: 366  PGVPGDAGMPGE--RGEAGHRGSAGALGPQG--PPGAPGVRGFQGQKGSMGDPGLPGPQG 421
             G  GD G PG   RGE G  G  G  G  G    G PG+ G QG+ G  G PGLPGP G
Sbjct: 988  RGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPG 1047

Query: 422  LRGDVGDRGPGGAAGPKGDQGIAGSDGLPGD 452
                     P G   P      A     PG+
Sbjct: 1048 ---------PPGQCDPSQCAYFASLAARPGN 1069



 Score =  292 bits (747), Expect = 8e-79
 Identities = 198/515 (38%), Positives = 232/515 (45%), Gaps = 113/515 (21%)

Query: 268 GERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAP 327
           G +GP   R           K  PG+   +GEPG  G+DG  G PGL G+ GE G  G P
Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279

Query: 328 GEKGPNGLPGLPGRAGSKGEKGERGRAGEL------------GEAGPSGEPGVP------ 369
           GEKG  GLPG PG  G +GEKG++G  GEL            GEAGP+G PG+P      
Sbjct: 280 GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 339

Query: 370 ----------------GDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGD 413
                           GD G+PGE G  G  G  G  GP GPPGA G  G  G  G+ G+
Sbjct: 340 TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGN 399

Query: 414 PGLP---------GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLP---GDKGELGPSGL 461
           PG P         GP G  G  G RG  G  G +G++G AG +G P   G +G+ G  GL
Sbjct: 400 PGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGL 459

Query: 462 VGPKGES--------GSRGELGPKGTQGPNGTSGVQGVP-----------GPPGPLGLQG 502
            GP G+         GS G  GP GT+G  G  G+ G P           GPPGP G  G
Sbjct: 460 PGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 519

Query: 503 VPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRP------ 556
             G PG  G PG PG +    R   L   +    I  LA  +     PG  G P      
Sbjct: 520 DKGSPGSRGLPGFPGPQGPAGR-DGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFK 578

Query: 557 ------------------GPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDP------ 592
                             G AGPPG PGPPG  G  G++G  G  G  G+ GD       
Sbjct: 579 GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVP 638

Query: 593 ---GPRGNQGDRGDKGAAGA-------GLDGPEGDQGPQGPQGVPG-------TSKDGQD 635
              GP GN G  G  G AGA       G  G EG  GPQGP G+PG         +DG+ 
Sbjct: 639 GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 698

Query: 636 GAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGA 670
           G PGEPG  G+PGLPG  GA+G PG    +   GA
Sbjct: 699 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA 733



 Score =  204 bits (520), Expect = 2e-52
 Identities = 141/354 (39%), Positives = 172/354 (48%), Gaps = 65/354 (18%)

Query: 347 EKGERGRAGELGEAGPSGEPG-VPGDAGMPGERGEAGHRGSAGALGPQGPPG-------- 397
           E  ++G  G  G    S  P  V     MP  +G  GH  SA ALG QGP          
Sbjct: 179 ENVDQGAQGACGRGNTSVLPSSVAPQCSMP--KG-TGHEFSA-ALGTQGPADQRADARAS 234

Query: 398 -------APGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLP 450
                  APG++   G+ G  G+ GLPG  GLRG++G++G  G  G KG+ G+ G+ G P
Sbjct: 235 CILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP 294

Query: 451 G------DKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGV----QGVPGPPGPLGL 500
           G      D+GE G  GL G KG+ G +GE GP G  G  GT+ +      +PG  GP G 
Sbjct: 295 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE 354

Query: 501 QGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAG 560
           +G PG+PG  G  G PG E   Q      G        Q  AH   P A G+ G PG  G
Sbjct: 355 KGDPGLPGEPGLQGRPG-ELGPQGPTGPPGAK-----GQEGAH-GAPGAAGNPGAPGHVG 407

Query: 561 PPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA----GLDGPEG 616
            PGP GPPGS+G PG RG PG                 G+RG+KGAAG     G  GP G
Sbjct: 408 APGPSGPPGSVGAPGLRGTPG---------------KDGERGEKGAAGEEGSPGPVGPRG 452

Query: 617 DQGPQGPQGVPGTSKDGQDGAPGEPGPPGD---------PGLPGAIGAQGTPGI 661
           D G  G  G PG  KDG+ G  G PG PG          PG+PG+ G++G PGI
Sbjct: 453 DPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI 506



 Score =  118 bits (295), Expect = 2e-26
 Identities = 69/146 (47%), Positives = 75/146 (51%), Gaps = 22/146 (15%)

Query: 12   LLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPG 71
            L  LL ++  A      G PGPPGPPG  G PG+ G  GE G PG  G  GP G  G  G
Sbjct: 927  LAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKG 986

Query: 72   KPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGP 131
            + G  G PG PGV GL G  GPPG  G PGE         PG    GLPG PG       
Sbjct: 987  ERGAKGDPGAPGV-GLRGEMGPPGIPGQPGE---------PGYAKDGLPGIPGP------ 1030

Query: 132  PGGIGLRGPPGPSGLPGLPGPPGPPG 157
                  +G  GP+G PGLPGPPGPPG
Sbjct: 1031 ------QGETGPAGHPGLPGPPGPPG 1050



 Score =  107 bits (268), Expect = 3e-23
 Identities = 88/275 (32%), Positives = 115/275 (41%), Gaps = 57/275 (20%)

Query: 416 LPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGP----SGLVGPKGESGSR 471
           L GP+    +  D+G  GA G +G+  +  S   P      G     S  +G +G +  R
Sbjct: 170 LLGPRTDPWENVDQGAQGACG-RGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQR 228

Query: 472 GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGG 531
            +             G++ + G PG  G  G+PG PG+ G+                   
Sbjct: 229 ADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGE------------------- 269

Query: 532 MISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGD 591
            I EQ              G  GRPG  G  G PG PG    PG RG  G +G  GELG 
Sbjct: 270 -IGEQ--------------GLAGRPGEKGEAGLPGAPG---FPGVRGEKGDQGEKGELGL 311

Query: 592 PGPRGNQGDRGDKGAAGA-GLDGPE----------GDQGPQGPQGVPGT-SKDGQDGAPG 639
           PG +G++G++G+ G AG  GL G            G+QGP+G +G PG   + G  G PG
Sbjct: 312 PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 371

Query: 640 E---PGPPGDPGLPGAIGAQGTPGICDTSACQGAV 671
           E    GP G PG  G  GA G PG        G V
Sbjct: 372 ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV 406


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  544 bits (1401), Expect = e-154
 Identities = 306/670 (45%), Positives = 355/670 (52%), Gaps = 74/670 (11%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP---------PGPKGAPGKPGKPGEAGLP 79
            G  GP G  G PG  G  G DG AGPPG  GP         PGPKG PG PGK G  G P
Sbjct: 919  GERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHP 978

Query: 80   GLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEAGVSGPPGGIGLR 138
            G  G  G  G+ GPPGP G  G +G  G  GP G  G  G PGPPGE G+ G  G  G +
Sbjct: 979  GQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTK 1038

Query: 139  GPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGPPGPPGMPGFKGPTGY 197
            G PGP+GLPG  GPPG  G PG  G+  P GA  L+  +  PPGPPGP G PG +GP G 
Sbjct: 1039 GDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLK-GNEGPPGPPGPAGSPGERGPAGA 1097

Query: 198  KGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIG------F 251
             G  G  G+ G +G PGP G  G PG  G QGP G  GL GP+G PG  GP+G       
Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGD 1157

Query: 252  RGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGE------------ 299
            +G  G PG  G  GD+GE+GP G  GP+G +G+PGP G  G  GP G+            
Sbjct: 1158 KGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP 1217

Query: 300  ---PGMPGKDGQNGVPGLDGQKGEAGR------NGAPGEKGPNGLPGLPGRAGSKGEKGE 350
               PG PG  G  G+PG  G+KGE G        G PG +GP+G PG  G  G  G  G 
Sbjct: 1218 RGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGN 1277

Query: 351  RGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGS 410
             G  GE GE G +GEPG+PG+ G PG +GE G +G +G  G  GPPG  G  G  G KGS
Sbjct: 1278 PGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGS 1337

Query: 411  MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGS 470
             G  G PG  G  G+ G  G  G  G KGD G  G  G PG  GE GPSG  G +G  G 
Sbjct: 1338 PGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGP 1397

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG 530
             G  G +G +G  G +G++G PG  GP+G QG PG PG  G  G+PG             
Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGP------------ 1445

Query: 531  GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELG 590
              + EQ              G  G PGP GPPGP GPPG  G  G  GP G +G  G +G
Sbjct: 1446 --VGEQ--------------GLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIG 1489

Query: 591  DPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLP 650
              GP G QG++GD+G     L GP+G  GP+G QG+ G S  G  G PG PG PG PG  
Sbjct: 1490 LIGPPGEQGEKGDRG-----LPGPQGSSGPKGEQGITGPS--GPIGPPGPPGLPGPPGPK 1542

Query: 651  GAIGAQGTPG 660
            GA G+ G  G
Sbjct: 1543 GAKGSSGPTG 1552



 Score =  541 bits (1395), Expect = e-154
 Identities = 323/736 (43%), Positives = 380/736 (51%), Gaps = 113/736 (15%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGP------KGAPGKPGKPGEAGLPGLP 82
            G PGP GPPGPPG  G+ G DGE GP GLPG PGP      KG PG PG PG  G+ G P
Sbjct: 646  GDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQP 705

Query: 83   GVDGLTGRDGPPGP---------KGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPG 133
            G  G  G  G PGP         +G PG +G++GPPG  G  GK  PG PG  G  GPPG
Sbjct: 706  GPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK--PGLPGMPGADGPPG 763

Query: 134  GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGPPGPPGMPGFK 192
              G  GPPG  G  G PGP GP G PG  GV   +G   L+       G  G  G PGFK
Sbjct: 764  HPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTK----GEKGEDGFPGFK 819

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGL------PGSVGLQGPRGLRGLPGPLGPPGDR 246
            G  G KG++GE+G  G +G+ GP GP G       PG +G  G +G  G+PG  G PG +
Sbjct: 820  GDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ 879

Query: 247  GPIGFRGPPGIPGA---------PGKAGDRGERGP---EGFRGPKGDLGRPGPKGTPGVA 294
            GP G  G PG PGA         PGK G RG+RGP    G RGP+G  G+PGPKG  G  
Sbjct: 880  GPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGD 939

Query: 295  GPSGEPGM------------------PGKDGQNGVPGLDGQKGEAG-------------- 322
            GP+G PG                   PG  G++G+PG  GQ+GE G              
Sbjct: 940  GPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVV 999

Query: 323  -------------RNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVP 369
                           G PG  GP G  GLPG AG +G KG+ G AG  G+ GP G  G P
Sbjct: 1000 GPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFP 1059

Query: 370  GDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDR 429
            GD G+PG  G  G +G+ G  GP GP G+PG RG  G  G +G PG PGPQG  G  G++
Sbjct: 1060 GDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEK 1119

Query: 430  GPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQ 489
               GA G KG QG AG DGL G  G  GP+G VGP GE G +GE+G  G +G  G  G Q
Sbjct: 1120 ---GAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQ 1176

Query: 490  GVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SEQRIRELCGGMISEQIAQLAAHL 544
            G PGP GP G  G PG  G  G+PG  G++       ++  R   G      +  L    
Sbjct: 1177 GPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPP 1236

Query: 545  RKPLAPGSIGRPGPAGPP------------GPPGPPGSIGHPGA---RGPPGYRGPTGEL 589
             +    G +G+ GP GPP            GP GPPG IG+PGA   +G PG  G  G  
Sbjct: 1237 GEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP 1296

Query: 590  GDPGPRGNQGDRGDKGAAG----AGLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGPP 644
            G+ GP G +G+RG+KG +G    AG  GP+G  G  GP+G PG     G  G PGEPGP 
Sbjct: 1297 GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPA 1356

Query: 645  GDPGLPGAIGAQGTPG 660
            G  G PG  G  G PG
Sbjct: 1357 GQDGPPGDKGDDGEPG 1372



 Score =  541 bits (1393), Expect = e-153
 Identities = 317/689 (46%), Positives = 349/689 (50%), Gaps = 104/689 (15%)

Query: 28   VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGL 87
            +G+ G  G  GPPG  G+DG +G  G  G  G PGP G PG+ GK G  GLPG PG  G 
Sbjct: 822  MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP 881

Query: 88   TGRDGPPGPKGAPGERGSLGPPGPPGLGGK----------------GLPGPPGEAGVSGP 131
             G  G PG  GA GE+G  G PG PG  G+                G PGP G +G  GP
Sbjct: 882  KGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941

Query: 132  PGGIGLRGPPGPSGLPGLPGPPGPPGP------PGHPGVLPEGATDLQCPSICPPGPPGP 185
             G  G RGP GP G  G PGP GPPGP      PGHPG    G T  Q       G  GP
Sbjct: 942  AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPG--QRGETGFQ-------GKTGP 992

Query: 186  PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQ---------------GP 230
            PG PG  GP G  GE G +G+ G  G PGPPG  GLPG  G +               GP
Sbjct: 993  PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGP 1052

Query: 231  RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT 290
             GLRG PG  G PG  G +G +G  G PG PG AG  GERGP G  GP G  GRPGP+G 
Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGP 1112

Query: 291  PGVAGPSGEPGMPGKDGQNGVPGLDGQ---KGEAGRNGAPGEKGPNGLPGLPGRAGSKGE 347
            PG AG  G PG  G  G  G  GL G     G AG  G PGE G  G  G PG+ GSKG+
Sbjct: 1113 PGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGD 1172

Query: 348  KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ 407
            KGE+G  G  G  GP G+PG  G  G PG RG+ G  G  G  GP+G PG PG  G QG 
Sbjct: 1173 KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232

Query: 408  KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE 467
                  PG PG +G  GDVG  GP G  GP+G  G  G+DG  G  G +G  G VG KGE
Sbjct: 1233 ------PGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGE 1286

Query: 468  SGSRGE---------LGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK 518
             G  GE          GPKG +G  G SG  G  GPPGP G  G  G  G  G  G PG 
Sbjct: 1287 PGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGD 1346

Query: 519  EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPP------GPPGSIG 572
                                           PG  G PGPAG  GPP      G PG  G
Sbjct: 1347 -------------------------------PGPPGEPGPAGQDGPPGDKGDDGEPGQTG 1375

Query: 573  HPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPGTSK 631
             PG  G PG  GP G+ G PGP G +G +G+KGA G AGL+GP G  GP GPQG PG  K
Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPG--K 1433

Query: 632  DGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
             G DG  G PGP G+ GLPG+ G  G PG
Sbjct: 1434 PGPDGLRGIPGPVGEQGLPGSPGPDGPPG 1462



 Score =  536 bits (1382), Expect = e-152
 Identities = 318/687 (46%), Positives = 352/687 (51%), Gaps = 98/687 (14%)

Query: 27   RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDG 86
            R G  G PGP GPPG+ G+ G+ G  G PG  GP G  G PG PG  GE G  G PG  G
Sbjct: 848  RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPG 907

Query: 87   LTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSG 145
              G+ GP GP+G  G RG  G PGP G  GG G  GPPGE G +GP G  G  GP GP  
Sbjct: 908  PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGP-- 965

Query: 146  LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205
                PGPPG  G PGHPG    G T  Q  +    GPPGPPG+ G +GPTG   E G +G
Sbjct: 966  ----PGPPGKDGLPGHPG--QRGETGFQGKT----GPPGPPGVVGPQGPTG---ETGPMG 1012

Query: 206  KDGEKGDPGPPGPAGLPGSVGLQG---------------PRGLRGLPGPLGPPGDRGPIG 250
            + G  G PGPPG  GLPG  G +G               P GLRG PG  G PG  G +G
Sbjct: 1013 ERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALG 1072

Query: 251  FRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNG 310
             +G  G PG PG AG  GERGP G  GP G  GRPGP+G PG AG  G PG  G  G  G
Sbjct: 1073 LKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1132

Query: 311  VPGLDGQ---KGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPG 367
              GL G     G AG  G PGE G  G  G PG+ GSKG+KGE+G  G  G  GP G+PG
Sbjct: 1133 RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPG 1192

Query: 368  VPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVG 427
              G  G PG RG+ G  G  G  GP+G PG PG  G QG       PG PG +G  GDVG
Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL------PGPPGEKGETGDVG 1246

Query: 428  DRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELG---------PKG 478
              GP G  GP+G  G  G+DG  G  G +G  G VG KGE G  GE G         PKG
Sbjct: 1247 QMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306

Query: 479  TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538
             +G  G SG  G  GPPGP G  G  G  G  G  G PG                     
Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGD-------------------- 1346

Query: 539  QLAAHLRKPLAPGSIGRPGPAGPPGPPGP------PGSIGHPGARGPPGYRGPTGELGDP 592
                       PG  G PGPAG  GPPG       PG  G PG  G PG  GP G+ G P
Sbjct: 1347 -----------PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPP 1395

Query: 593  GPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGP-------- 643
            GP G +G +G+KGA G AGL+GP G  GP GPQG PG  K G DG  G PGP        
Sbjct: 1396 GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPG--KPGPDGLRGIPGPVGEQGLPG 1453

Query: 644  -PGDPGLPGAIGAQGTPGICDTSACQG 669
             PG  G PG +G  G PG+   S  +G
Sbjct: 1454 SPGPDGPPGPMGPPGLPGLKGDSGPKG 1480



 Score =  520 bits (1340), Expect = e-147
 Identities = 302/663 (45%), Positives = 337/663 (50%), Gaps = 86/663 (12%)

Query: 29   GLPGPPGPPGPPGKPG---------QDGIDGEAGPPGLPG------------PPGPKGAP 67
            G PGP GPPGPPGK G         + G  G+ GPPG PG            P G +G P
Sbjct: 958  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHP 1017

Query: 68   GKPGKPGEAGLPGL---------PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKG 118
            G PG PGE GLPGL         PG  GL G+DGPPG +G PG+RG  GP G  GL  KG
Sbjct: 1018 GPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL--KG 1075

Query: 119  LPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-------PEGATD 171
              GPPG  G +G PG  G  G  GP G+PG PGP GPPGP G  G         P G   
Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135

Query: 172  LQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPR 231
            LQ P +  PGP GP G PG  G  G  GE G+ G  G+KG+ GPPGP G  G +G  GP 
Sbjct: 1136 LQGP-VGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPS 1194

Query: 232  GLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTP 291
            G  G PGP G  G  G  G  GP G PG PG  G +G  GP G +G  GD+G+ GP G P
Sbjct: 1195 GADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPP 1254

Query: 292  GVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGER 351
            G  GPS   G PG DG  G PG  G  G  G  G PGE G    PGLPG  G  G KGER
Sbjct: 1255 GPRGPS---GAPGADGPQGPPGGIGNPGAVGEKGEPGEAGE---PGLPGEGGPPGPKGER 1308

Query: 352  GRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSM 411
               GE GE+GPSG  G PG  G PG+ G  G  G  G  G  GPPG PG  G  G  G  
Sbjct: 1309 ---GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDK 1365

Query: 412  GDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR 471
            GD G PG  G  G  G+ GP G  G +G  G AG +G  G+KG  G +GL GP G++G  
Sbjct: 1366 GDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI 1425

Query: 472  GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGG 531
            G  G  G  GP+G  G+      PGP+G QG+PG PG  G PG  G              
Sbjct: 1426 GPQGAPGKPGPDGLRGI------PGPVGEQGLPGSPGPDGPPGPMG-------------- 1465

Query: 532  MISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGD 591
                           P  PG  G  GP G  G PG  G IG PG +G  G RG  G  G 
Sbjct: 1466 --------------PPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1511

Query: 592  PGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTS-KDGQDGAPGEPGPPGDPGLP 650
             GP+G QG  G  G  G    GP G  GP GP+G  G+S   G  G  G PGPPG PG P
Sbjct: 1512 SGPKGEQGITGPSGPIGP--PGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569

Query: 651  GAI 653
            G +
Sbjct: 1570 GEV 1572



 Score =  496 bits (1277), Expect = e-140
 Identities = 306/730 (41%), Positives = 351/730 (48%), Gaps = 115/730 (15%)

Query: 30   LPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGV----- 84
            + GPPGP GP G PG  G     GP G  G PG +G PG+PG PG  GLPG PG      
Sbjct: 467  IEGPPGPEGPAGLPGPPGT---MGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLP 523

Query: 85   ----------------------------------------DGLTGRDGPPGP------KG 98
                                                     GLTGR GP GP      KG
Sbjct: 524  FRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG 583

Query: 99   APGE------RGSLGPPGPPG-------LGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSG 145
             PG+      RG  GPPGP G        G  G  G PG+ G  G  G  GL G PG  G
Sbjct: 584  EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKG 643

Query: 146  LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205
              G PGP GPPGPPG  G   E   D +      PG PGP G+ G KGP G  G  G  G
Sbjct: 644  HRGDPGPSGPPGPPGDDG---ERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG 700

Query: 206  KDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGP---LGPPGDRGPIGFRGPPGIPGA-- 260
             DG+ G  G  GP G PG  G QG  G +GLPGP   +GPPG++GP+G  G PG+PGA  
Sbjct: 701  MDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADG 760

Query: 261  ----PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDG 316
                PGK G  GE+G +G  GP+G +G PGP+G  G  G  G  G  G+ G++G PG  G
Sbjct: 761  PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG 820

Query: 317  Q---KGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGD-- 371
                KG+ G  G PG +G +G  G  GR G  G+ G  G  GE G+ G  G PG PG   
Sbjct: 821  DMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQG 880

Query: 372  -------AGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDP---------G 415
                    G PG  GE G RG+ G  GP+G  G  G RG +G +G  G P         G
Sbjct: 881  PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDG 940

Query: 416  LPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELG 475
              GP G RG  G +GP G  GPKG  G  G DGLPG  G+ G +G  G  G  G  G +G
Sbjct: 941  PAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000

Query: 476  PKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISE 535
            P+G  G  G  G +G PGPPGP G QG+PG+ G  G  G PG            G    +
Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGP----------AGLPGKD 1050

Query: 536  QIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPR 595
                L         PG +G  G  G  GPPGPPG  G PG RGP G  GP G  G PGP+
Sbjct: 1051 GPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQ 1110

Query: 596  GNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPG----TSKDGQDGAPGEPGPPGDPGLP 650
            G  G  G+KGA G  G  GP G  G QGP G+PG        G+DG  GE G PG  G  
Sbjct: 1111 GPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170

Query: 651  GAIGAQGTPG 660
            G  G QG PG
Sbjct: 1171 GDKGEQGPPG 1180



 Score =  457 bits (1176), Expect = e-128
 Identities = 296/704 (42%), Positives = 342/704 (48%), Gaps = 97/704 (13%)

Query: 37   PGPPGKPGQDGIDGEAGPPGLPGPPGPKGAP--GKPGKPGEAGLPGLPG-----VDGLTG 89
            P PP   G D ++GE     +         P       P E G PG+P       +G+ G
Sbjct: 389  PAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIG-PGMPANQDTIYEGIGG 447

Query: 90   RDGPPGPKGAPG--ERGSL--GPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSG 145
              G  G KG P   E G L  GPPGP G  G  LPGPPG  G +G  G  G RGPPG  G
Sbjct: 448  PRGEKGQKGEPAIIEPGMLIEGPPGPEGPAG--LPGPPGTMGPTGQVGDPGERGPPGRPG 505

Query: 146  LPGLPGPPGPPGP-------------PGHPGVL-----PEGATDLQCPSICPPGPPGPPG 187
            LPG  G PGPPG               G  G +      +    LQ   +   GP GP G
Sbjct: 506  LPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMG 565

Query: 188  MPGFKGPTG------YKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLG 241
            + G  GP G       KGE G+VG  G +G  GPPGPAG PG  G  G  G RG+PG  G
Sbjct: 566  LTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTG 625

Query: 242  PPGDR---------GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPG 292
            P GDR         G  G RG PG  G PG  GD GERG +G  GP+G  G PGP+G  G
Sbjct: 626  PKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG 685

Query: 293  VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEK---GPNGLPGLPGRAGSKGEKG 349
              GP G PG PG  G +G PG  G  G  G  G PG++   G  GLPG  G  G  GEKG
Sbjct: 686  PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG 745

Query: 350  ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGAL---GPQGPPGAPGVRGFQG 406
              G+ G  G  G  G PG PG  G PGE+G  G  G  G +   GP+G  GA G+RG +G
Sbjct: 746  PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKG 805

Query: 407  QKGSMGDPGLP------GPQGLRGDVGDRGPGGAAGPKGDQGIAGSD------GLPGDKG 454
             KG  G+ G P      G +G RG++G  GP G  GP+G +G  G +      G PG+KG
Sbjct: 806  TKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKG 865

Query: 455  ELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVP------GVPG 508
            +LG  GL G  G  G +G +G  G  G NG  G +G PG PGP G +G        G  G
Sbjct: 866  KLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRG 925

Query: 509  ITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP-GSIGRPGPAGPPGPPGP 567
            ITGKPG  G    +        G   E         R P  P G  G PGP GPPGPPG 
Sbjct: 926  ITGKPGPKGNSGGDGP-----AGPPGE---------RGPNGPQGPTGFPGPKGPPGPPGK 971

Query: 568  PGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG----AGLDGPEGDQGPQGP 623
             G  GHPG RG  G++G TG  G PG  G QG  G+ G  G     G  GP G+QG  G 
Sbjct: 972  DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGL 1031

Query: 624  QGVPGTSKD-------GQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
             G  GT  D       G+DG PG  G PGD GLPG +GA G  G
Sbjct: 1032 AGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKG 1075



 Score =  442 bits (1136), Expect = e-124
 Identities = 257/586 (43%), Positives = 297/586 (50%), Gaps = 78/586 (13%)

Query: 25   AQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP------------GPPGPKGAPGKPGK 72
            A + G  G PGP G PGK G  G+ G  G  GLP            GPPGP G  G PG+
Sbjct: 1032 AGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGE 1091

Query: 73   PGEAGLPGLPGVDGLTGRDGPPGP---KGAPGERGSLGPPGPPGLGGK-GLPGPP----- 123
             G AG  G  G+ G  G  GPPGP   KGAPGE+G  GP G  GL G  GLPGP      
Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP 1151

Query: 124  ----------GEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDL- 172
                      GE G  G  G  G +GPPGP+G  G  G PGP G  G PG  P G   L 
Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG--PRGQQGLF 1209

Query: 173  -QCPSICP---PGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQ 228
             Q     P   PGPPGP G+ G  GP G KGE G+VG+ G  G PGP GP+G PG+ G Q
Sbjct: 1210 GQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQ 1269

Query: 229  GPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPK 288
            GP G  G PG +   G++G  G  G PG+PG  G  G +GERG +G  GP G  G PGPK
Sbjct: 1270 GPPGGIGNPGAV---GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPK 1326

Query: 289  GTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEK 348
            G PG  GP G PG  G  G    PG  G+ G AG++G PG+KG +G PG  G  G  GE 
Sbjct: 1327 GPPGDDGPKGSPGPVGFPGD---PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEP 1383

Query: 349  GERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQK 408
            G  G  G+ G  GP+G  G  G+ G  GE G  G  G  G +GPQG PG PG  G +G  
Sbjct: 1384 GPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIP 1443

Query: 409  GSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGES 468
            G +G+ GLP      G  G  GP G  GP G  G+ G  G  G+KG  G  GL+GP GE 
Sbjct: 1444 GPVGEQGLP------GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQ 1497

Query: 469  GSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIREL 528
            G +G+ G  G QG +G  G QG+ GP GP+G  G PG+PG  G  G  G           
Sbjct: 1498 GEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSG-------- 1549

Query: 529  CGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHP 574
                                  G  G  G  GPPGPPGPPG +  P
Sbjct: 1550 --------------------PTGPKGEAGHPGPPGPPGPPGEVIQP 1575



 Score =  397 bits (1021), Expect = e-110
 Identities = 233/501 (46%), Positives = 265/501 (52%), Gaps = 56/501 (11%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPG------------LPGPPGPK 64
            GE   A  A  +G+PG PGP GPPG  G+ G  GE GP G            LPGP GP 
Sbjct: 1090 GERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPV 1149

Query: 65   GAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124
            G PG+ G  GE G PG  G  G  G  GPPGP G    +G +G PGP G  G+  PGP G
Sbjct: 1150 GPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP---QGPIGQPGPSGADGE--PGPRG 1204

Query: 125  EAGVSGPPGGIGLRG---PPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICP- 179
            + G+ G  G  G RG   PPGP GL GLPGPPG  G  G  G + P G    + PS  P 
Sbjct: 1205 QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPG 1264

Query: 180  -PGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPG 238
              GP GPPG  G  G  G KGE GE G+ G  G+ GPPGP G  G  G  GP G  G PG
Sbjct: 1265 ADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPG 1324

Query: 239  PLGPPGDRGP------IGFRGPPGIPGAPGKAG------DRGERGPEGFRGPKGDLGRPG 286
            P GPPGD GP      +GF G PG PG PG AG      D+G+ G  G  G  G  G PG
Sbjct: 1325 PKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPG 1384

Query: 287  P------KGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPG 340
            P      +G PG AGP G  G  G  G+ G+ G  G+ G  G  GAPG+ GP+GL G+PG
Sbjct: 1385 PSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPG 1444

Query: 341  RAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPG 400
                 GE+G  G  G  G  GP G PG+PG  G  G +GE GH G  G +GP G      
Sbjct: 1445 PV---GEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGE----- 1496

Query: 401  VRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG 460
                QG+KG   D GLPGPQG  G  G++G  G +GP G  G  G  G PG KG  G SG
Sbjct: 1497 ----QGEKG---DRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSG 1549

Query: 461  LVGPKGESGSRGELGPKGTQG 481
              GPKGE+G  G  GP G  G
Sbjct: 1550 PTGPKGEAGHPGPPGPPGPPG 1570



 Score =  255 bits (652), Expect = 8e-68
 Identities = 147/311 (47%), Positives = 164/311 (52%), Gaps = 26/311 (8%)

Query: 16   LGELLAAAGAQRVGLPGPPGPPGPP---GKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK 72
            +GE      A   GLPG  GPPGP    G+ G+ G  G AGPPG  GPPG  G  G PG 
Sbjct: 1281 VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGP 1340

Query: 73   PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPP 132
             G  G PG PG  G  G+DGPPG KG  GE G  G PGP G  G    GPPG+ G  GP 
Sbjct: 1341 VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPS--GPPGKRGPPGPA 1398

Query: 133  GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192
            G  G +G  G  G  GL GPPG  GP G     P+GA          PG PGP G+ G  
Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIG-----PQGA----------PGKPGPDGLRGIP 1443

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLP---GPLGPPGDRGPI 249
            GP    GEQG  G  G  G PGP GP GLPG  G  GP+G +G P   G +GPPG++G  
Sbjct: 1444 GPV---GEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500

Query: 250  GFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQN 309
            G RG PG  G+ G  G++G  GP G  GP G  G PGP G  G  G SG  G  G+ G  
Sbjct: 1501 GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHP 1560

Query: 310  GVPGLDGQKGE 320
            G PG  G  GE
Sbjct: 1561 GPPGPPGPPGE 1571



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 46/121 (38%), Positives = 57/121 (47%), Gaps = 10/121 (8%)

Query: 564 PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGL--DGPEGDQGPQ 621
           P   P  IG     G P  +    E G  GPRG +G +G+      G+  +GP G +GP 
Sbjct: 423 PTSSPSEIGP----GMPANQDTIYE-GIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPA 477

Query: 622 GPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGS 681
           G  G PGT   G  G  G+PG  G PG PG  GA G PG   T        GG G+ +GS
Sbjct: 478 GLPGPPGTM--GPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGD-AGS 534

Query: 682 R 682
           +
Sbjct: 535 K 535


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  538 bits (1385), Expect = e-153
 Identities = 333/786 (42%), Positives = 383/786 (48%), Gaps = 156/786 (19%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLP---GPPGPKGA---PGKPGKPGEAGLPGLP 82
            G+ GP GP GPPG PG+ G DGEAG PG     GPPGP+GA   PG PG PG  G  G P
Sbjct: 234  GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYP 293

Query: 83   GVDGL------------------TGRDGPPGPKGAPGERGSLGP------------PGPP 112
            G+DG                    G  GP GP+G PGERG  GP            PGP 
Sbjct: 294  GLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA 353

Query: 113  G-------LGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGV- 164
            G        GG G PG PG  G +GP G  G  G  GP G PG PG PGP G  G+PG  
Sbjct: 354  GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413

Query: 165  -LPEGATDLQCPSICP----PGPPGPPGMPGFKGPTGYKGEQGE------VGKDGEKGDP 213
             +P        P I      PGP GPPG  G  GP G KG+ GE       G+ G KG+P
Sbjct: 414  GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473

Query: 214  GPPGPAGLPGSVGLQGPRGLRGLP---GPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGER 270
            GP GP G PG  G +G RG RG P   GP+GPPG+RG  G RG PG  G  G  G  GER
Sbjct: 474  GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 533

Query: 271  GPEGFRGPK---GDLGRPGPKGTPGVAGPSGEP------------GMPGKDGQNGVPGLD 315
            GP G  GPK   GD GRPG  G PG  G +G P            G PG+DG+ G PG  
Sbjct: 534  GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 593

Query: 316  GQKGE---------AGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGE- 365
            G +G+          G NG PG+ G  GLPG PG  G  G+ GE G AG  G AGP+GE 
Sbjct: 594  GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 653

Query: 366  -----------------------------PGVPGDAGMP------GERGEAGHRGSAGAL 390
                                          GVPG+AG P      GERG  G RGS GA 
Sbjct: 654  GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 713

Query: 391  GPQGP---PGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGS- 446
            G QGP   PG PG  G +G  G  G PG  GP GL+G  G+RG  G AGPKGD+G  G  
Sbjct: 714  GLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEK 773

Query: 447  --DGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP------GPPGPL 498
              +G PG  G  G +G +GP G +G+ GE G  G  GP G++G +G P      GPPGP 
Sbjct: 774  GPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPA 833

Query: 499  GLQGVPGV---PGITGKPGVPGKEA--------------SEQRIRELCGGMISEQIAQLA 541
            G  G PG    PG  G+ G  G++                 Q    + G   +       
Sbjct: 834  GFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP 893

Query: 542  AHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDR 601
                 P A G +G PG  G PGPPGPPG  G  G +G  G  GP G  G+PG +G  G  
Sbjct: 894  GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 953

Query: 602  GDKGAAGAGLDGPEGDQGPQGPQGVPG-------TSKDGQDGAPGEPGPPGDPGLPGAIG 654
            G+KG  G   DGP G +GP GPQG+ G         + G+ G PG PGP G+PG  GA G
Sbjct: 954  GEKGEPGD--DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 1011

Query: 655  AQGTPG 660
            A G  G
Sbjct: 1012 ASGDRG 1017



 Score =  535 bits (1377), Expect = e-152
 Identities = 330/717 (46%), Positives = 368/717 (51%), Gaps = 92/717 (12%)

Query: 24   GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPG---PKGAPGKPGKPGEAGLPG 80
            G   +G PG  G PG  G PGQDG+ G  G PG  GP G   PKGA G PG+PGE GLPG
Sbjct: 499  GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558

Query: 81   LPGVDGLTGRDGPPG---PKGAPGERGSLGPPGPPGLGGK----GLPGP------PGEAG 127
              G+ G  G  GP G   P GAPGE G  GPPGP G  G+    G PGP      PG+AG
Sbjct: 559  ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618

Query: 128  VSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL----PEGATDLQCPSICPPGPP 183
              G PG  GLRG PG  G  G  GPPGP GP G  G      P G   L       PGPP
Sbjct: 619  EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL-------PGPP 671

Query: 184  GPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPP 243
            GPPG  G  G  G  GE G  G  G +G+ G PG  G PG+ GLQGPRGL G PG  GP 
Sbjct: 672  GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 731

Query: 244  GDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGD---LGRPGPKGTPG------VA 294
            G  GP G   PPG  G PG  G  GERG  G  GPKGD   +G  GP+G PG      + 
Sbjct: 732  GASGPAG---PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 788

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRA 354
            GP G PG  G +G+ G  G  G  G AG  GAPGE+G  G PG  G AG  G  G+ G  
Sbjct: 789  GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848

Query: 355  GELGEAGPSGEPGVPGD---AGMPGERGEAGHRGSAGALGPQGPPGA---PGVRGFQGQK 408
            GE GEAG  G+ G PG    +G PG +G  G  G  GA G QGPPGA   PG  G  G  
Sbjct: 849  GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908

Query: 409  GSMGDPGLPGP------QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLV 462
            GS G+PG PGP       G +G  GD GP G AG  G QG AG  G  G+ G+ GPSG  
Sbjct: 909  GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 968

Query: 463  GPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGV------------PGIT 510
            GP G  G  G+ G  G  G  G  G  G+PGP G  G QG PG             PG+T
Sbjct: 969  GPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 1028

Query: 511  GKPGVPGKEASEQRI----RELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPG--- 563
            G  G PG+E S        R+   G+  ++    A  +  P APG  G PGPAGP G   
Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGA--VGAPGAPGPPGSPGPAGPTGKQG 1086

Query: 564  ---------PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDG 613
                     P GP G  G  G +GP G RG  GE G+PG RG +G RG  G  G  G  G
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1146

Query: 614  PEGDQG------PQGPQGVPG----TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            P GDQG      P GP+G PG    + KDG +G PG  GPPG  G  G  G  G PG
Sbjct: 1147 PSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1203



 Score =  526 bits (1354), Expect = e-149
 Identities = 317/699 (45%), Positives = 353/699 (50%), Gaps = 100/699 (14%)

Query: 28  VGLPGPPGPPGPPGK---------------PGQDGIDGEAGPPGLPGPPGPKGAPGKPG- 71
           VG  GPPGP GP G+               PG  G DGE G PG PGPPGP G PG PG 
Sbjct: 116 VGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL 175

Query: 72  --------------KPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG---- 113
                         K G A L  + G  G  G  GPPGP GAPG +G  G PG PG    
Sbjct: 176 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV 235

Query: 114 ---LGGKGLPGP---PGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPE 167
              +G +G PGP   PG+ G +G PG  G RGPPGP G  G PG PG PG  GH G    
Sbjct: 236 SGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY--- 292

Query: 168 GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL 227
                             PG+ G KG  G  G +GE G  GE G PGP GP GLPG  G 
Sbjct: 293 ------------------PGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 334

Query: 228 QGP------RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGD 281
            GP      RG  G PGP GPPG  GP G  G PG PGA G+AG  G RGPEG +GP+G+
Sbjct: 335 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 394

Query: 282 LGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGR 341
                  GTPG  GP+G  G PG DG  G  G  G  G AG  G PG +GP G  G  G 
Sbjct: 395 ------PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448

Query: 342 AGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMP---GERGEAGHRGSAGALGPQGPP-- 396
            G KG+ GE G AG  GE GP GEPG  G  G P   GE G+ G RG  G +GP GPP  
Sbjct: 449 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 508

Query: 397 -GAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE 455
            GAPG RGF GQ G  G  G PG +G  G  G +G  G  G  G+ G+ G+ GL G  G+
Sbjct: 509 RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 568

Query: 456 LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGP------PGPLGLQGVPGVPGI 509
            GP G VGP G  G  G  GP G QG  G  GV G PGP      PG  G +G+PG PG+
Sbjct: 569 AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 628

Query: 510 TGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPG 569
            G PG  G+  +         G   E+  Q A     P   G  G PGP GPPG  G PG
Sbjct: 629 RGLPGKDGETGAAGPPGP--AGPAGERGEQGA-----PGPSGFQGLPGPPGPPGEGGKPG 681

Query: 570 SIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG----AGLDGPEGDQGPQGP-- 623
             G PG  G PG  GP GE G PG RG+ G +G +G  G     G DGP+G  GP GP  
Sbjct: 682 DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPG 741

Query: 624 -QGVPG-TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            QG PG     G+ GA G  GP GD G  G  G +G PG
Sbjct: 742 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780



 Score =  487 bits (1253), Expect = e-137
 Identities = 299/667 (44%), Positives = 337/667 (50%), Gaps = 93/667 (13%)

Query: 23   AGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLP 82
            AG Q  G  GP G PG  G+PG  G  G  G PG+ G PGPKGA G+PGK GE GLPG P
Sbjct: 569  AGPQ--GKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 626

Query: 83   GVDGLTGRDG------PPGPKGAPGERGSLG------------PPGPPGLGGK-GLPGPP 123
            G+ GL G+DG      PPGP G  GERG  G            PPGPPG GGK G  G P
Sbjct: 627  GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 686

Query: 124  GEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGP 182
            GEAG  G  G  G RG PG  G PG  G  GP G PG PG   P+GA+        P GP
Sbjct: 687  GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG-------PAGP 739

Query: 183  PGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGP 242
            PG  G PG +G  G +G  G  G  G++GD G  GP G PG  G +G  G  G PGP G 
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 243  PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEG---FRGPKGDLGRPGPKGTPGVAGPSGE 299
             G++G +G  GP G  GA G  G+RGE GP G   F GP G  G+PG KG  G AG  G+
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 300  PGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGP------------------NGLPGLPGR 341
             G PG  G +G PG  G  G  G  GA G +GP                  NG PG PG 
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919

Query: 342  AGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV 401
             G  G+ G +G  G+ G  G +GEPG+ G AG PGE+GE G  G +GA GP GP G  G 
Sbjct: 920  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979

Query: 402  RGF---QGQKGSMGDPGLPGP------QGLRGDVGDRGPGGAAGPKG---------DQGI 443
            RG     GQ+G  G PGLPGP      QG  G  GDRGP G  GP G          +G 
Sbjct: 980  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 1039

Query: 444  AGSDGLPG---------DKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGP 494
             G+DG PG         D+GE G  G  G  G  GS G  GP G QG  G +G QG  GP
Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099

Query: 495  PGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIG 554
             GP G +G+ G  G  G  G    EA E   R L G      +  L      P   G  G
Sbjct: 1100 SGPAGARGIQGPQGPRGDKG----EAGEPGERGLKGHRGFTGLQGLPG---PPGPSGDQG 1152

Query: 555  RPGPAGPPGPPGPPGSIGH---------PGARGPPGYRGPTGELGDPGPRGNQGDRGDKG 605
              GPAGP GP GPPG +G          PG  GPPG RG +GE G  GP GN G  G  G
Sbjct: 1153 ASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1212

Query: 606  AAGAGLD 612
              G G+D
Sbjct: 1213 PPGPGID 1219



 Score =  464 bits (1193), Expect = e-130
 Identities = 288/696 (41%), Positives = 330/696 (47%), Gaps = 119/696 (17%)

Query: 87  LTGRDGPPGPKGAPGERGSL----GPPGPPG-LGGKGLPGPPGEAGVSGPPGGIGLRGPP 141
           L    G PGPKG  GE G +    GP GPPG  G  G  GP G+ G  G  G  G RG  
Sbjct: 93  LATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 152

Query: 142 GPSGLPGLPGPPGPPGPPGHPGVLPEGATD----------------LQCPSICPPGPPGP 185
           G  G PG PGPPGPPGPPG PG+    A                  +Q P + P GP GP
Sbjct: 153 GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGP-MGPMGPRGP 211

Query: 186 PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGD 245
           PG  G  GP G++G  GE G+ G  G  GP GP G PG  G  G  G  G  G  GPPG 
Sbjct: 212 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 271

Query: 246 RGPIGFRGPPGIPGAPGKAGD---RGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGM 302
           +G  GF G PG+PG  G  G     G +G  G  G KG+ G PG  G+PG  GP G PG 
Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 331

Query: 303 PGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGP 362
            G+ G  G  G  G  G+ G  G PG  GP G PG PG  G+KGE G  G  G  G  GP
Sbjct: 332 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 391

Query: 363 SGEPGVPGD------------------------------AGMPGERGEAGHRGSAGALGP 392
            GEPG PG                                G PG RG  G +G+ G LGP
Sbjct: 392 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 451

Query: 393 QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDR---------------GPGGAAGP 437
           +G  G PG+ GF+G++G  G+PG  GPQG  G  G+                GP G  G 
Sbjct: 452 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 511

Query: 438 KGDQGIAGSDGLPGDK---GELGPSGLVGPKGESGS------------------RGELGP 476
            G++G  G DGL G K   GE GPSGL GPKG +G                    G+ GP
Sbjct: 512 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 571

Query: 477 KGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQ 536
           +G  GP+G  G  G PGPPGP G +G PGV G  G  G  G+            G   E+
Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP-----------GKAGEK 620

Query: 537 IAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRG 596
               A  LR    PG  G  G AGPPGP GP G  G  GA GP G++G  G  G PG  G
Sbjct: 621 GLPGAPGLRG--LPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 678

Query: 597 NQGDRGDKGAAGA-GLDGPEGD------------QGPQGPQGVPGT-SKDGQDGAPGEPG 642
             GD+G  G AGA GL GP G+            QG QGP+G+PGT   DG  GA G  G
Sbjct: 679 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 738

Query: 643 PPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678
           PPG  G PG  G  G  G    +  +G   G VGEK
Sbjct: 739 PPGAQGPPGLQGMPGERGAAGIAGPKGD-RGDVGEK 773



 Score =  461 bits (1186), Expect = e-129
 Identities = 279/625 (44%), Positives = 317/625 (50%), Gaps = 88/625 (14%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP------PGPKGAPGKPGKPGEAGLPGLP 82
            GLPGPPGPPG  GKPG  G+ GEAG PGL GP      PG +G+PG  G  G  GLPG P
Sbjct: 666  GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 725

Query: 83   GVDGLTGRDGPPGPKGA---------PGERGSLGPPGPPG-LGGKGLPGPPGEAGVSGPP 132
            G DG  G  GP GP GA         PGERG+ G  GP G  G  G  GP G  G  G  
Sbjct: 726  GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 785

Query: 133  GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192
            G  G  GPPGP+G  G  G  GPPGP G  G    GA   +     PPGP G  G PG  
Sbjct: 786  GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGA--RGAPG-ERGETGPPGPAGFAGPPGAD 842

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS---VGLQGPRGLRGLPGPLGPPGDRGPI 249
            G  G KGEQGE G+ G+ G PGP GP+G PG     G+ GP+G RG  GP G  G  G  
Sbjct: 843  GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 902

Query: 250  GFRGPPGI---PGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKD 306
            G  GPPG    PG PG  G  G+ GP+G RG  G  GR G  G  G AGP GE G PG D
Sbjct: 903  GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 962

Query: 307  GQNGVPGLDGQKGEAGRNGA---PGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPS 363
            G +G  G  G +G AG+ G    PG++G  G PGLPG +G  G++G  G +G+ G  GP 
Sbjct: 963  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022

Query: 364  GEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGP---- 419
            G PG+ G AG PG  G      S GA GP G  GA GV+G +G+ G++G PG PGP    
Sbjct: 1023 GPPGLTGPAGEPGREG------SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1076

Query: 420  --------QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR 471
                    QG RG+ G +GP G +GP G +GI G  G  GDKGE G  G  G KG  G  
Sbjct: 1077 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1136

Query: 472  G------ELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRI 525
            G        GP G QG +G +G  G  GPPGP+G  G  G  GI G  G PG        
Sbjct: 1137 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR------ 1190

Query: 526  RELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGP 585
                                     G  G  GPAGPPG PGPPG    PG  GP      
Sbjct: 1191 -------------------------GRSGETGPAGPPGNPGPPGP---PGPPGPGIDMSA 1222

Query: 586  TGELG--DPGPRGNQGDRGDKGAAG 608
               LG  + GP   Q  R D+ A G
Sbjct: 1223 FAGLGPREKGPDPLQYMRADQAAGG 1247



 Score =  397 bits (1019), Expect = e-110
 Identities = 228/516 (44%), Positives = 259/516 (50%), Gaps = 61/516 (11%)

Query: 4    PRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQD---GIDGEAGPP----- 55
            P A  P  L  + GE  AA  A   G  G  G  GP G PG+D   G+ G  GPP     
Sbjct: 740  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 56   -------GLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGP 108
                   G PGP G  GA G PG+ GE G PG  G  G  G DG PG KG  GE G  G 
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 109  PGPPG-LGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPE 167
             G PG  G  G PGP G  GV+GP G  G +GPPG +G PG  G  GPPG  G+      
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN------ 913

Query: 168  GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL 227
                        PGPPGPPG  G  GP G +G+ G  G+ GE G  GP GP G  G  G 
Sbjct: 914  ------------PGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 961

Query: 228  QGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP 287
             GP G  G PGP G  G RG +G  G  G  G PG  G  GE G +G  G  GD G PGP
Sbjct: 962  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021

Query: 288  KGTPGVAGPSGEPGMPGKDGQNGVPGLD------GQKGEAGRNGAPGEKGPNGLPGLPGR 341
             G PG+ GP+GEPG  G  G +G PG D      G +GE G  GAPG  GP G PG  G 
Sbjct: 1022 VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081

Query: 342  AGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV 401
             G +G++GE G  G +G +GP+G  G+ G  G  G++GEAG                PG 
Sbjct: 1082 TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE---------------PGE 1126

Query: 402  RGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGL 461
            RG +G +G  G  GLPGP G  GD G  GP G +GP+G  G  G  G  G  G  GP G 
Sbjct: 1127 RGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP 1186

Query: 462  VGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGP 497
             GP+G SG  G  GP G  GP       G PGPPGP
Sbjct: 1187 PGPRGRSGETGPAGPPGNPGP------PGPPGPPGP 1216



 Score =  338 bits (866), Expect = 1e-92
 Identities = 208/505 (41%), Positives = 243/505 (48%), Gaps = 75/505 (14%)

Query: 211 GDPGPPGPAGLPGSVGLQGPRGLRGLP-------GPLGPPGDRGPIGFRGPPGIPGAPGK 263
           G+  P  P  L  + G  GP+G +G P       GP GPPG +GP G +GP G  G  G+
Sbjct: 83  GECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE 142

Query: 264 AGDRGERGPEGFRGPKGDLGRPGPKGTP------------------------------GV 293
            G  G RG +G  G  G+ G PGP G P                              G 
Sbjct: 143 KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGP 202

Query: 294 AGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGR 353
            GP G  G PG  G  G  G  G  GE G  G  G  GP G PG PG+ G  GE G+ G+
Sbjct: 203 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 262

Query: 354 AGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGD 413
           AGE G  GP G  G PG  G+PG +   GHRG  G  G +G  GAPGV+G  G  G  G 
Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVK---GHRGYPGLDGAKGEAGAPGVKGESGSPGENGS 319

Query: 414 PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGS---------------DGLPGDKGELGP 458
           PG  GP+GL G+ G  GP GAAG +G+ G  G                 G PG KGE GP
Sbjct: 320 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379

Query: 459 SGLVGPKGESGSRGELGPKGTQGPNGTS---GVQGVPGPPGPLGLQGVPGVPGITGKPGV 515
           +G  GP+G  G RGE G  G+ GP G S   G  G+PG  G  G  G+ G PG  G  G 
Sbjct: 380 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439

Query: 516 PGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPG 575
           PG + +   +    G      IA            G  G PGPAGP G PGP G  G  G
Sbjct: 440 PGPQGATGPLGPK-GQTGEPGIAGFKGE------QGPKGEPGPAGPQGAPGPAGEEGKRG 492

Query: 576 ARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQD 635
           ARG PG  GP   +G PG RG  G+RG  G    GL GP+G  G +GP G+ G       
Sbjct: 493 ARGEPGGVGP---IGPPGERGAPGNRGFPGQ--DGLAGPKGAPGERGPSGLAGPK----- 542

Query: 636 GAPGEPGPPGDPGLPGAIGAQGTPG 660
           GA G+PG PG+PGLPGA G  G PG
Sbjct: 543 GANGDPGRPGEPGLPGARGLTGRPG 567



 Score =  256 bits (654), Expect = 5e-68
 Identities = 172/464 (37%), Positives = 199/464 (42%), Gaps = 82/464 (17%)

Query: 278 PKGDLGRPGPKGTPGVAGPSGEPGM-------------------PGKDGQNGVPGLDGQK 318
           P+   G   P     +A  SG+PG                    PG  G  G  G  G +
Sbjct: 78  PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137

Query: 319 GEAGRNGAPGEKGPNGLPGLPGRAGSKGE------------------------------- 347
           G+ G  GAPG +G +G PG PG  G  G                                
Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 197

Query: 348 --KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQ 405
             +G  G  G  G  GP+G PG  G  G PGE GE G  G  G  GP GPPG PG  G  
Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 257

Query: 406 GQKGSMGDPGLPGPQGLR---------GDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL 456
           G+ G  G+ G PGPQG R         G  G RG  G  G KG+ G  G  G  G  GE 
Sbjct: 258 GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 317

Query: 457 GPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVP 516
           G  G +GP+G  G RG  GP G  G  G  G  G  GPPGP+G  G PG PG  G  G  
Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 377

Query: 517 GKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGA 576
           G   +  R  E   G   E           P +PG  G  G  G  G PG  GS G PG 
Sbjct: 378 GPTGA--RGPEGAQGPRGEP--------GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 427

Query: 577 RGPPGY---RGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPG-TSK 631
            G PG+   RGP G  G  GP G +G  G+ G AG  G  GP+G+ GP GPQG PG   +
Sbjct: 428 AGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGE 487

Query: 632 DGQDGAPGEP------GPPGDPGLPGAIGAQGTPGICDTSACQG 669
           +G+ GA GEP      GPPG+ G PG  G  G  G+       G
Sbjct: 488 EGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531



 Score =  143 bits (361), Expect = 5e-34
 Identities = 98/260 (37%), Positives = 115/260 (44%), Gaps = 80/260 (30%)

Query: 459 SGLVGPKGESGSRGEL----GPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPG 514
           SG  GPKG+ G  G++    GPKG  GP G +G QG  G  G  G +G PG  G  G+PG
Sbjct: 97  SGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG 156

Query: 515 VPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGH- 573
            P                                     G PGP GPPGPPGPPG  G+ 
Sbjct: 157 TP-------------------------------------GNPGPPGPPGPPGPPGLGGNF 179

Query: 574 --------------------PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDG 613
                                G  GP G RGP G  G PGP+G QG+ G+ G  G  + G
Sbjct: 180 AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG--VSG 237

Query: 614 PEGDQGPQGPQGVPGTSKDGQDGAPGE------PGP------PGDPGLPGAIGAQGTPGI 661
           P G +GP GP G PG   DG+ G PG+      PGP      PG PGLPG  G +G PG+
Sbjct: 238 PMGPRGPPGPPGKPGD--DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGL 295

Query: 662 CDTSACQGAVLGGVGEKSGS 681
                  GA   GV  +SGS
Sbjct: 296 DGAKGEAGA--PGVKGESGS 313



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 55/138 (39%), Positives = 66/138 (47%), Gaps = 36/138 (26%)

Query: 547 PLAPGSI----GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRG 602
           P+ P  +    G+PGP G  G PG    I   G +GPPG   P G  G+ GPRG   DRG
Sbjct: 87  PICPTDLATASGQPGPKGQKGEPGDIKDI--VGPKGPPG---PQGPAGEQGPRG---DRG 138

Query: 603 DKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662
           DK           G++G  GP+G             GEPG PG+PG PG  G  G PG+ 
Sbjct: 139 DK-----------GEKGAPGPRG-----------RDGEPGTPGNPGPPGPPGPPGPPGLG 176

Query: 663 DTSACQGAVLGGVGEKSG 680
              A Q A  GG  EK+G
Sbjct: 177 GNFAAQMA--GGFDEKAG 192


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  536 bits (1382), Expect = e-152
 Identities = 332/705 (47%), Positives = 369/705 (52%), Gaps = 81/705 (11%)

Query: 29   GLPG---PPGPPG--PPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK----PGKPGEAGLP 79
            GLPG   P GPPG  PPG  G+ GI G AG PG PG PGPKG PG+    PGKPG  G P
Sbjct: 612  GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 80   GLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGG----- 134
            G  G  GL G  G PG  G PG  GS G PG PG+G  G PGP G  G+ GPPG      
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 135  -IGLRGPPGPSGLPG--------LPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGPPG 184
             IGL GPPGP G PG        LPGPPGPPG PG  G L P+G           PGPPG
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF-------PGPPG 784

Query: 185  PPGMPGFKGPTGYKGEQGEVGKDGEKGDPG--------PPGPAGLPGSVGLQGPRGLRGL 236
            PPG  G  G  G KG+ G  G+ G  G PG        PPGP G+PG +G  G  G+ G 
Sbjct: 785  PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 237  PGPLGPPG--DRGPIGFRGPPGIPGAPGKAGDRG------ERGPEGFRGPKGDLGRPGPK 288
             G  GPPG    GP G RG PGIPGAPG  G  G      + G  GF G KG++G  GP 
Sbjct: 845  KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPP 904

Query: 289  GTPG---VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G PG   + G SG PG+ G DG  G PGL G  GE G  G PG  GP G P  P   GSK
Sbjct: 905  GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG-PMDPNLLGSK 963

Query: 346  GEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQ 405
            GEKGE G  G  G +GP G  G+PGD G PG  G+ G  G  G  G  G PG PG+ G  
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 406  GQKGSMGDPGLPGPQGLRGDVGDRG-------PG--GAAGPKGDQGIA--GSDGLPGDKG 454
            G KG++GD G PGPQG+ G  G  G       PG  G  G KGD GI+  G  GLPG KG
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083

Query: 455  ELGPSGLVGPKGESGSRGELG------PKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPG 508
            E G  G  G  G  GS G+ G        G +G  G  G  G PGPPGP G+ G PG PG
Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143

Query: 509  ITGKPGVPGK--EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPG 566
            + G+PG  G      +       G    + I   A    +P  PG  G PGP G PG  G
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSG 1202

Query: 567  PPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGV 626
              G  G PG  G PG  GP GE G  G  G QG  G  G+ G  L+GP+G+ GPQGP G 
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262

Query: 627  PGT-SKDGQDGAPGE---------PGPPGDPGLPGAIGAQGTPGI 661
            PG    +G  G PG          PG PG PGLPG  G QG PG+
Sbjct: 1263 PGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1307



 Score =  535 bits (1378), Expect = e-152
 Identities = 324/731 (44%), Positives = 362/731 (49%), Gaps = 103/731 (14%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP--------PGPKGAPGKPG------KPG 74
            G PG PGPPG PG PG+ G++G  GPPG PGP        PGP G PG PG        G
Sbjct: 716  GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 75   EAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGP--- 131
            + G PG PG  G TG DG PGPKG  G  G  GP GPPGL G G+ GPPG  G+ GP   
Sbjct: 776  DRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 132  --------------PGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGA-------T 170
                          P G+ + GPPG  G PG+PG PGP GPPG PG LP  A       T
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG-LPGKAGASGFPGT 894

Query: 171  DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQ------------GEVGKDGEKGDPGPPGP 218
              +   + PPGPPGP G+PG  G  G KG+             GE G  GE G PGPPGP
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 219  --------------AGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA 264
                           GLPG  G+ GP+G +GLPG  G PG  G  G  GPPG  G PG  
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 265  GDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDG--------------QNG 310
            G  G  GP G +G  GD+G PGP+G  G  GPSG PG PG  G                G
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 311  VPGLDGQKGEAGRNGAPGEK------GPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSG 364
            +PGL G KGE G  G PG        G  GLPGLPG  G+KG+ G  G  G  G  GP G
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134

Query: 365  EPGVPGDAGMPGERGE---AGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL--PGP 419
              G PG+ G+PGE G     GH G  G  G +G PG  G+ G  GQKG  G PG   PGP
Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 420  QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGT 479
             GL G  G +G GG  G  G+ G+ G  G PG  G  G  G  GP G  G   E GPKG 
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE-GPKGN 1253

Query: 480  QGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SEQRIRELCGGMIS 534
             GP G  G  G+PGP GP GL G  G+ G  G PG PG         +Q    L G    
Sbjct: 1254 PGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGR 1313

Query: 535  EQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGE----LG 590
              +  +      P  PG  G  GP+G PG  GP G  G  G  GPPG  GP+G+     G
Sbjct: 1314 PGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1373

Query: 591  DPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGPPGDPGL 649
            D GP G  G  G KG  G    GP+G  GP GP G PG     G DGA G  G PG PG 
Sbjct: 1374 DAGPPGIPGQPGLKGLPGP--QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ 1431

Query: 650  PGAIGAQGTPG 660
            PG  G  G PG
Sbjct: 1432 PGTRGLDGPPG 1442



 Score =  508 bits (1308), Expect = e-144
 Identities = 327/817 (40%), Positives = 381/817 (46%), Gaps = 186/817 (22%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPG---PK-------------GAPGKPGK 72
            G+PG PG PG PG+PG+DG  G+ G  G PGPPG   P+             G PG PG+
Sbjct: 310  GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 73   PGEAGLPGLPGVDGLTGRDG-----PPGPKGAPGERGSLGPPGPPGL------------G 115
             GE G PG+ G  GL G  G     PPGP G PGERG  G  GPPG+            G
Sbjct: 370  KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429

Query: 116  GKGLPGPPG-------------EAGVSGPPG-------------------------GIGL 137
              GLPGPPG             E G  GPPG                         G G+
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 138  RGPPGPSGLPGLPGPPGPPGPPGHPGVLPE-GATDLQCPSICPPGPPGPPGMPGFKGPTG 196
             GPPG  GLPGLPGPPG  G PG  G   + GAT        P G PG PG PG  G  G
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATG-------PKGLPGIPGAPGAPGFPG 542

Query: 197  YKGEQGEV----GKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252
             KGE G++    G  G+KG+ G PG  GLPG  G  G  GL GLPGP G PG     G R
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 253  GPPGIPGAPGKAGDRGERGPEGFR-----------------------GPKGDLG------ 283
            GPPG PG PG  G+ G  GP GF                        GPKGD G      
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 284  -RPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGA--PGEKGPNGLPGLPG 340
             +PG  G PG  G  G PG PG  GQ G+PG+ G KGE G  G   PG  GP G PG+PG
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722

Query: 341  RAGSKGEKGE---RGRAGELGEAGPSGEPGV-----PGDAGMPGERGEAGHRGSAGALGP 392
              G+ G  G     G  G  G  GP GEPG      PG  G+PG +G  G +G  G  GP
Sbjct: 723  PPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782

Query: 393  QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG--DVGDRGPGGAAGPKGDQGIAGSDGLP 450
             GPPG  G+ G  G KG +G  G PGP G  G   +G +GP G  G  G  G  G  G+P
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 451  GDKGELGPSGL--------------------VGPKGESGSRGELGPKGTQGPNGTSGVQG 490
            G+KG+ GP GL                    +GP G  G  G+ G  G  G  G  G+ G
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 491  VPGPPGPLG---------------LQGVPGVPGITGK------PGVPGK----------- 518
             PGPPGPLG               LQG PG+PG TG+      PG+PG            
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGS 962

Query: 519  --EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGA 576
              E  E  +  + G    +    L      P  PG  G+PG  GPPGP G PG  G PG 
Sbjct: 963  KGEKGEPGLPGIPGVSGPKGYQGLPGD---PGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 577  RGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA----GLDGPEGDQGPQGPQGVPGTSKD 632
             GPPG +G  G++G PGP+G +G  G  G  G     GL G +GD+G  G   +      
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLP 1079

Query: 633  GQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG 669
            G  G PG PG PG+PG+ G++G  G PG+  T   +G
Sbjct: 1080 GPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116



 Score =  502 bits (1293), Expect = e-142
 Identities = 336/794 (42%), Positives = 382/794 (48%), Gaps = 166/794 (20%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
           GLPG PGP GPPG  GQ G DG  GPPG   P G +G PG PG PG  GLPG+PG DG  
Sbjct: 60  GLPGFPGPEGPPGPRGQKGDDGIPGPPG---PKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 89  GRDGPPGPKGAPGER---------GSLGPPGPPGLGG----------KGLPGPPGEAGVS 129
           G  G PG  G  GER         G  GPPGPPG+ G            LPGP G  G  
Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176

Query: 130 GPPGGIGLRGP---PGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPS--------IC 178
           GPPG  GL GP   PGP G PG PG  GPPGPPG PG       + Q P           
Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236

Query: 179 PPGPP-------------------------GPPGMPGFKGP-------TGYKGEQGE--- 203
           PPGPP                         GPPG PG +GP        G KGEQGE   
Sbjct: 237 PPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 204 ---VGKDGEKGD---PGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGP-------IG 250
               GKDGE G    PG PG  G PG  G  G +G +G  GP GPPG   P       IG
Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIG 356

Query: 251 FRGPPGIPGAPGKAGDR---GERGPEGFRGPKGD--LGRPGPKGTPGVAGPSGE------ 299
            +G  G+PG PG+ G+R   G +GP G  GP G   +G PGP G PG  G  G+      
Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI 416

Query: 300 --PGMPGKDGQNGVPGLDGQKGEAGRNGAPG----EKGPNGLPGLPGRAGSKGEKGERGR 353
             PG PG DGQ G PGL G  G AG +  P     E GP G PG PG  G +GE+G +G 
Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGD 476

Query: 354 AGE-------LGEAGPSGEPGVPGDAGMPGE---RGEAGHRGSAGALGPQGPPGAPGVRG 403
            G+        G +GP G+PG+PG  G PG     G+ G +G AGA GP+G PG PG  G
Sbjct: 477 KGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536

Query: 404 FQGQKGSMGDPG--LPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPG---------- 451
             G  GS G+PG  L  P G++GD G+ G  GA G  G  G  G DGLPG          
Sbjct: 537 APGFPGSKGEPGDILTFP-GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 452 --DKGELGPSGLVGPKGESGSRGELGPK--GTQGPNGTSGVQGVPGPPGPLGLQGVPGVP 507
              KGE GP G  G  G  G+ G +GP   G  GP G  G+QGV G PG  G+ G  G P
Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655

Query: 508 GIT----GKPGVPGKEASEQRI----------RELCGGMISEQIAQLAAHLRKPLAPGSI 553
           G T    GKPG+PG    +  +          +    G+   +       +  P  PG  
Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPK 715

Query: 554 GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGE-----LGDPGP------RGNQGDRG 602
           G PG  GPPG PG PG IG  G  GPPG+ GP GE      G PGP      +G  G +G
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 603 DKGAAG-------AGLD---------GPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD 646
           D+G  G        GLD         GP G  GP GP G+PG    G  G PG PGP G 
Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 647 PGLPGAIGAQGTPG 660
           PGL G  G +G PG
Sbjct: 836 PGLHGIPGEKGDPG 849



 Score =  467 bits (1201), Expect = e-131
 Identities = 294/675 (43%), Positives = 333/675 (49%), Gaps = 113/675 (16%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPG-----LPGPPGPKGAPGKPGKPGEAGLPGLPG 83
            G PGPPG PGP G+PG  GI GE G PG     +PGPPG +G+PG PG PG  G PG PG
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 84   VDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK-GLPGPPGEAGVSGPPGGIGLRGPPG 142
            + G  G  G PG KG  G  G  GPPGP G+ G+ G+PG  G+ G+ G PG  G  G  G
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 143  PSGLPGLPGPPGP--------------PGPPGHPGVL-PEGATDLQCPSICP-------- 179
              G PGLPGPPGP              PG PG PGV  P+G   L      P        
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 180  PGPPGP------PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG---SVGLQGP 230
            PGPPGP      PG PG  GP G KG  G++G  G +G  GPPGP+G+PG   S GL G 
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 231  RGLRGLPG--PLGPPGDRGPIGFRGPPGIPGAPG---KAGDRGERGPEGFRGPKGDLGRP 285
            +G +G PG   +G PG  GP G  G PG PG PG     GD G  G  G  G KG  G P
Sbjct: 1062 KGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP 1121

Query: 286  GPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G  GTPG  GP G  G PG  G  G PG  G  G  G+ G PGEKG  G  G+PG AG K
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 346  GEKGERGRA--------GELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPG 397
            GE G+ G          G  G+ G  G PG+PG+ G+PG +GE G  G  G  GP GPPG
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241

Query: 398  APG--VRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE 455
            +PG  + G +G  G  G PG PG  G  G  G  G GG  G KG+ G  G  GLPG KG+
Sbjct: 1242 SPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1301

Query: 456  LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGV 515
             GP GL G  G  G  G  G  G  G  G  G++G  G PG  G +G PG+ G  G PG+
Sbjct: 1302 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1361

Query: 516  PGKEASEQRIRELCG--GMISEQIAQLAAHLRKPLAPGSIGRPGPAGP---PGPPGPPGS 570
            PG       I+   G  G+              P  PG  G PGP GP   PGP GPPG 
Sbjct: 1362 PGPSGQSIIIKGDAGPPGI--------------PGQPGLKGLPGPQGPQGLPGPTGPPGD 1407

Query: 571  IGH---------------PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPE 615
             G                PG  G PG RG                          LDGP 
Sbjct: 1408 PGRNGLPGFDGAGGRKGDPGLPGQPGTRG--------------------------LDGPP 1441

Query: 616  GDQGPQGPQGVPGTS 630
            G  G QGP G PGTS
Sbjct: 1442 GPDGLQGPPGPPGTS 1456



 Score =  459 bits (1180), Expect = e-129
 Identities = 296/714 (41%), Positives = 354/714 (49%), Gaps = 86/714 (12%)

Query: 10  LLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK 69
           LL L L G+   AA              G  G+ G+ G  G  G PGLPG PGP+G PG 
Sbjct: 14  LLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP 73

Query: 70  PGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVS 129
            G+ G+ G+P            GPPGPKG  G  G  G PG PGL   G+PG  G  G  
Sbjct: 74  RGQKGDDGIP------------GPPGPKGIRGPPGLPGFPGTPGL--PGMPGHDGAPGPQ 119

Query: 130 GPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICP---PGPPGPP 186
           G PG  G +G  G  G PG PG  GPPGPPG PG+  E  + +      P   PG PGPP
Sbjct: 120 GIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP 179

Query: 187 GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL--QGPRGLRGLPGPLGPPG 244
           G+ G  GPTG  G  G  G  G  G PGPPG  G  G++GL  QGP+G +G  G  GPPG
Sbjct: 180 GIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPG 239

Query: 245 DRGPI-------------GFRGPPGIPGAPGKAGDRGERGPEGF-RGPKGDLGRPGPKGT 290
             G I             G +G PG  G PG  G RG  GP G  +G KG+ G PG +G 
Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK 299

Query: 291 PGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLP-GLPGRAGSKGEKG 349
           PG  G +G+PG+PG  G  G PG  G+ GE G+ G  G  GP GL    PG   + GEKG
Sbjct: 300 PGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKG 359

Query: 350 ERGRAGELGEAGPSGEPGVPGDAGMPGERGEA--------GHRGSAGALGPQGPPGA--P 399
             G  G  GE G  G PG+ G  G+PG  G A        G  G  G  G +GPPG   P
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 400 GVRGFQGQKGSMGDPGLPGPQGLR----GDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE 455
           G  G  GQ G+ G PG PGP G       ++ + GP G  G  GD+G+ G  G+ GDKG+
Sbjct: 420 GPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479

Query: 456 -----LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGIT 510
                +G +G+ GP G+ G  G  GP G+ G  G  G +G  G  GP GL G+PG PG  
Sbjct: 480 TCFNCIG-TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538

Query: 511 GKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP------PGP 564
           G PG  G+         + G             L  P APG  G PG  G       PGP
Sbjct: 539 GFPGSKGEPGDILTFPGMKGDK---------GELGSPGAPGLPGLPGTPGQDGLPGLPGP 589

Query: 565 PGPPGSIGHPGARGPPG------YRGPTGELGDPG--PRGNQGDRGDKGAAG----AGLD 612
            G PG I   G RGPPG        G  G +G PG  P G  G++G +G AG     G+ 
Sbjct: 590 KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIP 649

Query: 613 GPEGDQGPQ----GPQGVPGT-SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
           GP+GD G      G  G+PG   +DG  G PG+PG PG PGLPG  G++G PGI
Sbjct: 650 GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI 703



 Score =  419 bits (1077), Expect = e-117
 Identities = 248/569 (43%), Positives = 292/569 (51%), Gaps = 100/569 (17%)

Query: 28   VGLPGPPGPPGPPGKPGQDGI------DGEAGPPGLPGPPGPKGAPGKPGKPG------- 74
            +G+ GPPGPPGP G PG+ G+      DG  G PGLPGP G KG+ G+PG PG       
Sbjct: 898  MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 957

Query: 75   ----------EAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124
                      E GLPG+PGV G  G  G PG  G PG  G  G PGPPG   KG PG PG
Sbjct: 958  NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG--PKGNPGLPG 1015

Query: 125  EAGVSGPPG------------GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDL 172
            + G+ GPPG              G+ GPPGPSG+PG PG PG PG  G  G    G + +
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG--DPGISSI 1073

Query: 173  QCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGP---PGPAGLPGSVGLQG 229
              P +  PGP G PG+PG+ G  G KG  G+ G  G  G PG    PG  G PG+ G  G
Sbjct: 1074 GLPGL--PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 230  PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGD-----LGR 284
            P+G+ G PG  G PG+ GP+G  G PG PG PG+ G  G+ G  G  G KG+      G 
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 285  PGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRA-- 342
            PGP G PG++G  G+ G+PG  G    PGL G KGE G +G PG +GP G PG PG A  
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGN---PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE 1248

Query: 343  GSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA---LGPQGPPGAP 399
            G KG  G +G  G  G  GP G PG+PG+ G+ GE+G  G  G  G     G QGPPG  
Sbjct: 1249 GPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ 1308

Query: 400  GVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPG-------- 451
            G  G  G  G  GDPGLPG  G  G  G  G  G+AGP+G+ G+ G  G PG        
Sbjct: 1309 GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQS 1368

Query: 452  --DKGELGPSGLVGPKGESGSRGELGPKGTQGPNG------------------------- 484
               KG+ GP G+ G  G  G  G  GP+G  GP G                         
Sbjct: 1369 IIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1428

Query: 485  -----TSGVQGVPGPPGPLGLQGVPGVPG 508
                 T G+    GPPGP GLQG PG PG
Sbjct: 1429 PGQPGTRGLD---GPPGPDGLQGPPGPPG 1454



 Score =  416 bits (1069), Expect = e-116
 Identities = 241/513 (46%), Positives = 273/513 (53%), Gaps = 65/513 (12%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGV---- 84
            G+PG  GP G  G PG  G  G +G PGLPGPPGPKG PG PG+PG  G PGL G     
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032

Query: 85   --DGLTGRDGPPGPKGAPGERGSLGPPGPPG---------LGGKGLPGPPGEAGVSGPPG 133
               G  G +GPPGP G PG+ GS G PG  G         +G  GLPGP GE G+ G PG
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 134  GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKG 193
              G++G  G  GLPGLPG PG  G PG PG           P    PGPPGP G+ G  G
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF----------PGT--PGPPGPKGISGPPG 1140

Query: 194  PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPG--------PLGPPGD 245
              G  GE G VG  G  G PGPPG  G PG  G+ GP G +G PG        P G PG 
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 246  RGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPG--------PKGTPGVAGPS 297
             G  G  G PGIPG PG  G +GE G  GF G +G  G PG        PKG PG  GP 
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1260

Query: 298  GEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGEL 357
            G PG+PG +G  G+PG  G KGE G  G PG      LPGLPG  G +G  G +G  G  
Sbjct: 1261 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPG------LPGLPGLKGDQGPPGLQGNPGRP 1314

Query: 358  GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQG---PPGAPGVRGFQGQ----KGS 410
            G  G  G+PG+PG  G PG +G +G  GSAG  G  G   PPG PG+ G  GQ    KG 
Sbjct: 1315 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1374

Query: 411  MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGS 470
             G PG+PG  GL+G  G +GP G  GP G  G  G +GLPG        G  G KG+ G 
Sbjct: 1375 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF------DGAGGRKGDPGL 1428

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGV 503
             G+ G +G  GP G  G+Q   GPPGP G   V
Sbjct: 1429 PGQPGTRGLDGPPGPDGLQ---GPPGPPGTSSV 1458



 Score =  336 bits (861), Expect = 5e-92
 Identities = 223/545 (40%), Positives = 257/545 (47%), Gaps = 86/545 (15%)

Query: 180 PGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGP 239
           PG  G PG+PGF GP G  G +G+ G DG    PGPPGP G+      +GP GL G PG 
Sbjct: 53  PGLEGHPGLPGFPGPEGPPGPRGQKGDDGI---PGPPGPKGI------RGPPGLPGFPGT 103

Query: 240 LGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGF---RGPKGDLGRPGPKGTPG---- 292
            G PG  G  G  GP GIPG  G  G+RG  G  GF   +GP G  G PG KG PG    
Sbjct: 104 PGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIM 163

Query: 293 --VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE--K 348
             + GP G PG PG  G  G+PG  G  G  G  G PG  GP G PGLPG  G+ G   +
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 349 GERGRAGELGEAGPSGEPGVPGDAGMP-------GERGEAGHRGSAGALGPQGPPGAPGV 401
           G +G  GE G  GP G PG   +   P       G++G  G RG  G  G +GPPG PG 
Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG- 282

Query: 402 RGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG- 460
            G +G+KG  G+PG  G  G  G+ G  G  G  G  G  G  G DG  G KG+ GP G 
Sbjct: 283 -GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341

Query: 461 --LVGPK-------GESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLG--LQGVPGVPGI 509
             LV P+       GE G+ G  G  G +G  G  G+QG PG PGP G  + G PG PG 
Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401

Query: 510 TGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPG 569
            G+ G  G E                              P  I  PGP G  G PG PG
Sbjct: 402 PGERGQKGDEG-----------------------------PPGISIPGPPGLDGQPGAPG 432

Query: 570 SIGHPGARGP----------PGYRGPTGELGDPGPRGNQGDRGDKG-----AAGAGLDGP 614
             G PG  GP          PG  GP G  GD G +G QG +GDKG       G G+ GP
Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 615 EGDQGPQGPQGVPGT-SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLG 673
            G  G  G  G PG+    GQ G  G+ G  G  GLPG  GA G PG   +    G +L 
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 674 GVGEK 678
             G K
Sbjct: 553 FPGMK 557



 Score =  333 bits (855), Expect = 2e-91
 Identities = 200/427 (46%), Positives = 227/427 (53%), Gaps = 45/427 (10%)

Query: 24   GAQRVGLPGPPGP---PGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPG 80
            G   +GLPG PGP   PG PG PG  GI G  G PGLPG PG  GA G+PG PG  G PG
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 81   LPGVDGLTGRDGPPGPKGAPGE---RGSLGPPGPPGLGGK----GLPGPPGEAGV----- 128
             PG  G++G  G PG  G PG     G  G PGPPG  GK    G+PGP G+ G      
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 129  ---SGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGP 185
                GPPG  GL G  G  GLPG+PG PG PGP G PG    G   +Q     PPGPPG 
Sbjct: 1189 FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF--HGFPGVQ----GPPGPPGS 1242

Query: 186  PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGD 245
            PG P  +GP G  G QG  G+ G    PGP GP GLPG+ G++G +G  G PG  G PG 
Sbjct: 1243 PG-PALEGPKGNPGPQGPPGRPGL---PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298

Query: 246  RGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGK 305
            +G    +GPPG+ G PG+ G  G +G  G  G  G  G  GP G PG AGP GEPG+ G 
Sbjct: 1299 KGD---QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1355

Query: 306  DGQNGVPGLDGQ----KGEAGRNGAPGEKGPNGLP------GLPGRAGSKGEKGERGRAG 355
             G  G+PG  GQ    KG+AG  G PG+ G  GLP      GLPG  G  G+ G  G  G
Sbjct: 1356 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1415

Query: 356  ELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV-RGFQGQKGSMGDP 414
              G  G  G+PG+P   G PG RG  G  G  G  GP GPPG   V  GF   + S    
Sbjct: 1416 FDGAGGRKGDPGLP---GQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTD 1472

Query: 415  GLPGPQG 421
                PQG
Sbjct: 1473 APQCPQG 1479



 Score =  322 bits (826), Expect = 6e-88
 Identities = 195/423 (46%), Positives = 217/423 (51%), Gaps = 47/423 (11%)

Query: 28   VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE---------AGL 78
            VG PG PG PG PG  GQ G+ G  G PG PGP G  G PG PG PGE          G 
Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 79   PGLPGVDGLTGRDGPPGPKGAPGERG--SLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIG 136
            PG PG  G  G+DG PGP G  GE G    G PGPPGL   GL G  G+ G+ G PG  G
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL--PGLSGQKGDGGLPGIPGNPG 1217

Query: 137  LRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTG 196
            L GP G  G  G PG  GPPGPPG PG   EG           PGP GPPG PG  GP G
Sbjct: 1218 LPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKG-------NPGPQGPPGRPGLPGPEG 1270

Query: 197  YKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPG 256
              G  G  G  GEKG+PG PG  GLPG  G QGP GL+      G PG  G  G +G PG
Sbjct: 1271 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ------GNPGRPGLNGMKGDPG 1324

Query: 257  IPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGE----------PGMPGKD 306
            +PG PG  G +G  G  G  GP+G+ G  GP G PG+ GPSG+          PG+PG+ 
Sbjct: 1325 LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQP 1384

Query: 307  GQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEP 366
            G  G+PG  G +G  G  G PG+ G NGLPG  G  G KG+ G  G+ G  G  GP G  
Sbjct: 1385 GLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD 1444

Query: 367  GVPGDAGMPGERGEAG----HRGSAGALGPQGPPGAPGV-RGF-----QGQKGSMG-DPG 415
            G+ G  G PG    A      R S     PQ P G   V  GF     QG K + G D G
Sbjct: 1445 GLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLG 1504

Query: 416  LPG 418
              G
Sbjct: 1505 TAG 1507



 Score =  281 bits (719), Expect = 1e-75
 Identities = 158/341 (46%), Positives = 186/341 (54%), Gaps = 33/341 (9%)

Query: 15   LLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP--GPPGPKGAPGKPGK 72
            L GE     G    G PGPPG  G PG+ G  G  G+ G PG P  G PGP G PG  G+
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203

Query: 73   PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPP 132
             G+ GLPG+PG  GL G  G PG  G PG +   GPPGPPG  G  L GP G  G  GPP
Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ---GPPGPPGSPGPALEGPKGNPGPQGPP 1260

Query: 133  GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192
            G  GL GP GP GLPG  G  G  G PG PG+                  PG PG+ G +
Sbjct: 1261 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGL------------------PGLPGLKGDQ 1302

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252
            GP G +G  G  G +G KGDPG P   G+PG  G++GP    G+PG  GP G+ G IG  
Sbjct: 1303 GPPGLQGNPGRPGLNGMKGDPGLP---GVPGFPGMKGP---SGVPGSAGPEGEPGLIGPP 1356

Query: 253  GPPGIPGAPGKA-GDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
            GPPG+PG  G++   +G+ GP G  G  G  G PGP+G  G+ GP+G PG PG+   NG+
Sbjct: 1357 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR---NGL 1413

Query: 312  PGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG 352
            PG DG  G  G  G PG+ G  GL G PG  G +G  G  G
Sbjct: 1414 PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  535 bits (1379), Expect = e-152
 Identities = 332/708 (46%), Positives = 369/708 (52%), Gaps = 84/708 (11%)

Query: 29   GLPG---PPGPPG--PPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK----PGKPGEAGLP 79
            GLPG   P GPPG  PPG  G+ GI G AG PG PG PGPKG PG+    PGKPG  G P
Sbjct: 612  GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 80   GLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGG----- 134
            G  G  GL G  G PG  G PG  GS G PG PG+G  G PGP G  G+ GPPG      
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 135  -IGLRGPPGPSGLPG--------LPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGPPG 184
             IGL GPPGP G PG        LPGPPGPPG PG  G L P+G           PGPPG
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF-------PGPPG 784

Query: 185  PPGMPGFKGPTGYKGEQGEVGKDGEKGDPG--------PPGPAGLPGSVGLQGPRGLRGL 236
            PPG  G  G  G KG+ G  G+ G  G PG        PPGP G+PG +G  G  G+ G 
Sbjct: 785  PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 237  PGPLGPPG--DRGPIGFRGPPGIPGAPGKAGDRG------ERGPEGFRGPKGDLGRPGPK 288
             G  GPPG    GP G RG PGIPGAPG  G  G      + G  GF G KG++G  GP 
Sbjct: 845  KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPP 904

Query: 289  GTPG---VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G PG   + G SG PG+ G DG  G PGL G  GE G  G PG  GP G P  P   GSK
Sbjct: 905  GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG-PMDPNLLGSK 963

Query: 346  GEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQ 405
            GEKGE G  G  G +GP G  G+PGD G PG  G+ G  G  G  G  G PG PG+ G  
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 406  GQKGSMGDPGLPGPQGLRGDVGDRG-------PG--GAAGPKGDQGIA--GSDGLPGDKG 454
            G KG++GD G PGPQG+ G  G  G       PG  G  G KGD GI+  G  GLPG KG
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083

Query: 455  ELGPSGLVGPKGESGSRGELG------PKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPG 508
            E G  G  G  G  GS G+ G        G +G  G  G  G PGPPGP G+ G PG PG
Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143

Query: 509  ITGKPGVPGK--EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPG 566
            + G+PG  G      +       G    + I   A    +P  PG  G PGP G PG  G
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSG 1202

Query: 567  PPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGV 626
              G  G PG  G PG  GP GE G  G  G QG  G  G+ G  L+GP+G+ GPQGP G 
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262

Query: 627  PG----TSKDGQDGAPGE---------PGPPGDPGLPGAIGAQGTPGI 661
            PG       +G  G PG          PG PG PGLPG  G QG PG+
Sbjct: 1263 PGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1310



 Score =  534 bits (1376), Expect = e-152
 Identities = 324/733 (44%), Positives = 362/733 (49%), Gaps = 104/733 (14%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP--------PGPKGAPGKPG------KPG 74
            G PG PGPPG PG PG+ G++G  GPPG PGP        PGP G PG PG        G
Sbjct: 716  GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 75   EAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGP--- 131
            + G PG PG  G TG DG PGPKG  G  G  GP GPPGL G G+ GPPG  G+ GP   
Sbjct: 776  DRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 132  --------------PGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGA-------T 170
                          P G+ + GPPG  G PG+PG PGP GPPG PG LP  A       T
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG-LPGKAGASGFPGT 894

Query: 171  DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQ------------GEVGKDGEKGDPGPPGP 218
              +   + PPGPPGP G+PG  G  G KG+             GE G  GE G PGPPGP
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 219  --------------AGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA 264
                           GLPG  G+ GP+G +GLPG  G PG  G  G  GPPG  G PG  
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 265  GDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDG--------------QNG 310
            G  G  GP G +G  GD+G PGP+G  G  GPSG PG PG  G                G
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 311  VPGLDGQKGEAGRNGAPGEK------GPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSG 364
            +PGL G KGE G  G PG        G  GLPGLPG  G+KG+ G  G  G  G  GP G
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134

Query: 365  EPGVPGDAGMPGERGE---AGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL--PGP 419
              G PG+ G+PGE G     GH G  G  G +G PG  G+ G  GQKG  G PG   PGP
Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 420  QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGS--RGELGPK 477
             GL G  G +G GG  G  G+ G+ G  G PG  G  G  G  GP G  G    G  G  
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254

Query: 478  GTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SEQRIRELCGGM 532
            G QGP G  G QG+PGP GP GL G  G+ G  G PG PG         +Q    L G  
Sbjct: 1255 GPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1314

Query: 533  ISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGE---- 588
                +  +      P  PG  G  GP+G PG  GP G  G  G  GPPG  GP+G+    
Sbjct: 1315 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1374

Query: 589  LGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGPPGDP 647
             GD GP G  G  G KG  G    GP+G  GP GP G PG     G DGA G  G PG P
Sbjct: 1375 KGDAGPPGIPGQPGLKGLPGP--QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLP 1432

Query: 648  GLPGAIGAQGTPG 660
            G PG  G  G PG
Sbjct: 1433 GQPGTRGLDGPPG 1445



 Score =  503 bits (1296), Expect = e-142
 Identities = 327/815 (40%), Positives = 377/815 (46%), Gaps = 183/815 (22%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPG---PK-------------GAPGKPGK 72
            G+PG PG PG PG+PG+DG  G+ G  G PGPPG   P+             G PG PG+
Sbjct: 310  GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 73   PGEAGLPGLPGVDGLTGRDG-----PPGPKGAPGERGSLGPPGPPGL------------G 115
             GE G PG+ G  GL G  G     PPGP G PGERG  G  GPPG+            G
Sbjct: 370  KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429

Query: 116  GKGLPGPPG-------------EAGVSGPPG-------------------------GIGL 137
              GLPGPPG             E G  GPPG                         G G+
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 138  RGPPGPSGLPGLPGPPGPPGPPGHPGVLPE-GATDLQCPSICPPGPPGPPGMPGFKGPTG 196
             GPPG  GLPGLPGPPG  G PG  G   + GAT        P G PG PG PG  G  G
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATG-------PKGLPGIPGAPGAPGFPG 542

Query: 197  YKGEQGEV----GKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252
             KGE G++    G  G+KG+ G PG  GLPG  G  G  GL GLPGP G PG     G R
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 253  GPPGIPGAPGKAGDRGERGPEGFR-----------------------GPKGDLG------ 283
            GPPG PG PG  G+ G  GP GF                        GPKGD G      
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 284  -RPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGA--PGEKGPNGLPGLPG 340
             +PG  G PG  G  G PG PG  GQ G+PG+ G KGE G  G   PG  GP G PG+PG
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722

Query: 341  RAGSKGEKGE---RGRAGELGEAGPSGEPGV-----PGDAGMPGERGEAGHRGSAGALGP 392
              G+ G  G     G  G  G  GP GEPG      PG  G+PG +G  G +G  G  GP
Sbjct: 723  PPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782

Query: 393  QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG--DVGDRGPGGAAGPKGDQGIAGSDGLP 450
             GPPG  G+ G  G KG +G  G PGP G  G   +G +GP G  G  G  G  G  G+P
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 451  GDKGELGPSGL--------------------VGPKGESGSRGELGPKGTQGPNGTSGVQG 490
            G+KG+ GP GL                    +GP G  G  G+ G  G  G  G  G+ G
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 491  VPGPPGPLG---------------LQGVPGVPGITGK------PGVPGK----------- 518
             PGPPGPLG               LQG PG+PG TG+      PG+PG            
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGS 962

Query: 519  --EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGA 576
              E  E  +  + G    +    L      P  PG  G+PG  GPPGP G PG  G PG 
Sbjct: 963  KGEKGEPGLPGIPGVSGPKGYQGLPGD---PGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 577  RGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKDGQD 635
             GPPG +G  G++G PGP+G +G  G  G  G  G  G  G +G +G  G+      G  
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLP 1079

Query: 636  GAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGA 670
            G  GEPG PG PG PG  G+ G PG+       GA
Sbjct: 1080 GPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA 1114



 Score =  502 bits (1293), Expect = e-142
 Identities = 336/794 (42%), Positives = 382/794 (48%), Gaps = 166/794 (20%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
           GLPG PGP GPPG  GQ G DG  GPPG   P G +G PG PG PG  GLPG+PG DG  
Sbjct: 60  GLPGFPGPEGPPGPRGQKGDDGIPGPPG---PKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 89  GRDGPPGPKGAPGER---------GSLGPPGPPGLGG----------KGLPGPPGEAGVS 129
           G  G PG  G  GER         G  GPPGPPG+ G            LPGP G  G  
Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176

Query: 130 GPPGGIGLRGP---PGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPS--------IC 178
           GPPG  GL GP   PGP G PG PG  GPPGPPG PG       + Q P           
Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236

Query: 179 PPGPP-------------------------GPPGMPGFKGP-------TGYKGEQGE--- 203
           PPGPP                         GPPG PG +GP        G KGEQGE   
Sbjct: 237 PPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 204 ---VGKDGEKGD---PGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGP-------IG 250
               GKDGE G    PG PG  G PG  G  G +G +G  GP GPPG   P       IG
Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIG 356

Query: 251 FRGPPGIPGAPGKAGDR---GERGPEGFRGPKGD--LGRPGPKGTPGVAGPSGE------ 299
            +G  G+PG PG+ G+R   G +GP G  GP G   +G PGP G PG  G  G+      
Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI 416

Query: 300 --PGMPGKDGQNGVPGLDGQKGEAGRNGAPG----EKGPNGLPGLPGRAGSKGEKGERGR 353
             PG PG DGQ G PGL G  G AG +  P     E GP G PG PG  G +GE+G +G 
Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGD 476

Query: 354 AGE-------LGEAGPSGEPGVPGDAGMPGE---RGEAGHRGSAGALGPQGPPGAPGVRG 403
            G+        G +GP G+PG+PG  G PG     G+ G +G AGA GP+G PG PG  G
Sbjct: 477 KGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536

Query: 404 FQGQKGSMGDPG--LPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPG---------- 451
             G  GS G+PG  L  P G++GD G+ G  GA G  G  G  G DGLPG          
Sbjct: 537 APGFPGSKGEPGDILTFP-GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 452 --DKGELGPSGLVGPKGESGSRGELGPK--GTQGPNGTSGVQGVPGPPGPLGLQGVPGVP 507
              KGE GP G  G  G  G+ G +GP   G  GP G  G+QGV G PG  G+ G  G P
Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655

Query: 508 GIT----GKPGVPGKEASEQRI----------RELCGGMISEQIAQLAAHLRKPLAPGSI 553
           G T    GKPG+PG    +  +          +    G+   +       +  P  PG  
Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPK 715

Query: 554 GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGE-----LGDPGP------RGNQGDRG 602
           G PG  GPPG PG PG IG  G  GPPG+ GP GE      G PGP      +G  G +G
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 603 DKGAAG-------AGLD---------GPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD 646
           D+G  G        GLD         GP G  GP GP G+PG    G  G PG PGP G 
Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 647 PGLPGAIGAQGTPG 660
           PGL G  G +G PG
Sbjct: 836 PGLHGIPGEKGDPG 849



 Score =  466 bits (1200), Expect = e-131
 Identities = 296/678 (43%), Positives = 335/678 (49%), Gaps = 116/678 (17%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPG-----LPGPPGPKGAPGKPGKPGEAGLPGLPG 83
            G PGPPG PGP G+PG  GI GE G PG     +PGPPG +G+PG PG PG  G PG PG
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 84   VDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK-GLPGPPGEAGVSGPPGGIGLRGPPG 142
            + G  G  G PG KG  G  G  GPPGP G+ G+ G+PG  G+ G+ G PG  G  G  G
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 143  PSGLPGLPGPPGP--------------PGPPGHPGVL-PEGATDLQCPSICP-------- 179
              G PGLPGPPGP              PG PG PGV  P+G   L      P        
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 180  PGPPGP------PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG---SVGLQGP 230
            PGPPGP      PG PG  GP G KG  G++G  G +G  GPPGP+G+PG   S GL G 
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 231  RGLRGLPG--PLGPPGDRGPIGFRGPPGIPGAPG---KAGDRGERGPEGFRGPKGDLGRP 285
            +G +G PG   +G PG  GP G  G PG PG PG     GD G  G  G  G KG  G P
Sbjct: 1062 KGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP 1121

Query: 286  GPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G  GTPG  GP G  G PG  G  G PG  G  G  G+ G PGEKG  G  G+PG AG K
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 346  GEKGERGRA--------GELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPG 397
            GE G+ G          G  G+ G  G PG+PG+ G+PG +GE G  G  G  GP GPPG
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241

Query: 398  APG--VRGFQGQKGSMGDPGLPGPQGLRGDVGDRG---PGGAAGPKGDQGIAGSDGLPGD 452
            +PG  + G +G  G  G PG PG QGL G  G  G    GG  G KG+ G  G  GLPG 
Sbjct: 1242 SPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301

Query: 453  KGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGK 512
            KG+ GP GL G  G  G  G  G  G  G  G  G++G  G PG  G +G PG+ G  G 
Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1361

Query: 513  PGVPGKEASEQRIRELCG--GMISEQIAQLAAHLRKPLAPGSIGRPGPAGP---PGPPGP 567
            PG+PG       I+   G  G+              P  PG  G PGP GP   PGP GP
Sbjct: 1362 PGLPGPSGQSIIIKGDAGPPGI--------------PGQPGLKGLPGPQGPQGLPGPTGP 1407

Query: 568  PGSIGH---------------PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLD 612
            PG  G                PG  G PG RG                          LD
Sbjct: 1408 PGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG--------------------------LD 1441

Query: 613  GPEGDQGPQGPQGVPGTS 630
            GP G  G QGP G PGTS
Sbjct: 1442 GPPGPDGLQGPPGPPGTS 1459



 Score =  459 bits (1180), Expect = e-129
 Identities = 296/714 (41%), Positives = 354/714 (49%), Gaps = 86/714 (12%)

Query: 10  LLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK 69
           LL L L G+   AA              G  G+ G+ G  G  G PGLPG PGP+G PG 
Sbjct: 14  LLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP 73

Query: 70  PGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVS 129
            G+ G+ G+P            GPPGPKG  G  G  G PG PGL   G+PG  G  G  
Sbjct: 74  RGQKGDDGIP------------GPPGPKGIRGPPGLPGFPGTPGL--PGMPGHDGAPGPQ 119

Query: 130 GPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICP---PGPPGPP 186
           G PG  G +G  G  G PG PG  GPPGPPG PG+  E  + +      P   PG PGPP
Sbjct: 120 GIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP 179

Query: 187 GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL--QGPRGLRGLPGPLGPPG 244
           G+ G  GPTG  G  G  G  G  G PGPPG  G  G++GL  QGP+G +G  G  GPPG
Sbjct: 180 GIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPG 239

Query: 245 DRGPI-------------GFRGPPGIPGAPGKAGDRGERGPEGF-RGPKGDLGRPGPKGT 290
             G I             G +G PG  G PG  G RG  GP G  +G KG+ G PG +G 
Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK 299

Query: 291 PGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLP-GLPGRAGSKGEKG 349
           PG  G +G+PG+PG  G  G PG  G+ GE G+ G  G  GP GL    PG   + GEKG
Sbjct: 300 PGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKG 359

Query: 350 ERGRAGELGEAGPSGEPGVPGDAGMPGERGEA--------GHRGSAGALGPQGPPGA--P 399
             G  G  GE G  G PG+ G  G+PG  G A        G  G  G  G +GPPG   P
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 400 GVRGFQGQKGSMGDPGLPGPQGLR----GDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE 455
           G  G  GQ G+ G PG PGP G       ++ + GP G  G  GD+G+ G  G+ GDKG+
Sbjct: 420 GPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479

Query: 456 -----LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGIT 510
                +G +G+ GP G+ G  G  GP G+ G  G  G +G  G  GP GL G+PG PG  
Sbjct: 480 TCFNCIG-TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538

Query: 511 GKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP------PGP 564
           G PG  G+         + G             L  P APG  G PG  G       PGP
Sbjct: 539 GFPGSKGEPGDILTFPGMKGDK---------GELGSPGAPGLPGLPGTPGQDGLPGLPGP 589

Query: 565 PGPPGSIGHPGARGPPG------YRGPTGELGDPG--PRGNQGDRGDKGAAG----AGLD 612
            G PG I   G RGPPG        G  G +G PG  P G  G++G +G AG     G+ 
Sbjct: 590 KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIP 649

Query: 613 GPEGDQGPQ----GPQGVPGT-SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
           GP+GD G      G  G+PG   +DG  G PG+PG PG PGLPG  G++G PGI
Sbjct: 650 GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI 703



 Score =  417 bits (1073), Expect = e-116
 Identities = 248/572 (43%), Positives = 293/572 (51%), Gaps = 103/572 (18%)

Query: 28   VGLPGPPGPPGPPGKPGQDGI------DGEAGPPGLPGPPGPKGAPGKPGKPG------- 74
            +G+ GPPGPPGP G PG+ G+      DG  G PGLPGP G KG+ G+PG PG       
Sbjct: 898  MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 957

Query: 75   ----------EAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124
                      E GLPG+PGV G  G  G PG  G PG  G  G PGPPG   KG PG PG
Sbjct: 958  NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG--PKGNPGLPG 1015

Query: 125  EAGVSGPPG------------GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDL 172
            + G+ GPPG              G+ GPPGPSG+PG PG PG PG  G  G    G + +
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG--DPGISSI 1073

Query: 173  QCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGP---PGPAGLPGSVGLQG 229
              P +  PGP G PG+PG+ G  G KG  G+ G  G  G PG    PG  G PG+ G  G
Sbjct: 1074 GLPGL--PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 230  PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGD-----LGR 284
            P+G+ G PG  G PG+ GP+G  G PG PG PG+ G  G+ G  G  G KG+      G 
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 285  PGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRA-- 342
            PGP G PG++G  G+ G+PG  G    PGL G KGE G +G PG +GP G PG PG A  
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGN---PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE 1248

Query: 343  ---GSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA---LGPQGPP 396
               G+ G +G  GR G  G  GP G PG+PG+ G+ GE+G  G  G  G     G QGPP
Sbjct: 1249 GPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1308

Query: 397  GAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPG----- 451
            G  G  G  G  G  GDPGLPG  G  G  G  G  G+AGP+G+ G+ G  G PG     
Sbjct: 1309 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1368

Query: 452  -----DKGELGPSGLVGPKGESGSRGELGPKGTQGPNG---------------------- 484
                  KG+ GP G+ G  G  G  G  GP+G  GP G                      
Sbjct: 1369 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1428

Query: 485  --------TSGVQGVPGPPGPLGLQGVPGVPG 508
                    T G+    GPPGP GLQG PG PG
Sbjct: 1429 PGLPGQPGTRGLD---GPPGPDGLQGPPGPPG 1457



 Score =  413 bits (1061), Expect = e-115
 Identities = 240/510 (47%), Positives = 265/510 (51%), Gaps = 56/510 (10%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGV---- 84
            G+PG  GP G  G PG  G  G +G PGLPGPPGPKG PG PG+PG  G PGL G     
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032

Query: 85   --DGLTGRDGPPGPKGAPGERGSLGPPGPPG---------LGGKGLPGPPGEAGVSGPPG 133
               G  G +GPPGP G PG+ GS G PG  G         +G  GLPGP GE G+ G PG
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 134  GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKG 193
              G++G  G  GLPGLPG PG  G PG PG           P    PGPPGP G+ G  G
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF----------PGT--PGPPGPKGISGPPG 1140

Query: 194  PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPG--------PLGPPGD 245
              G  GE G VG  G  G PGPPG  G PG  G+ GP G +G PG        P G PG 
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 246  RGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPG--------PKGTPGVAGPS 297
             G  G  G PGIPG PG  G +GE G  GF G +G  G PG        PKG PG  GP 
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1260

Query: 298  GEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGEL 357
            G PG  G  G  G PGL G  G  G  G PG+ G  GLPGL G  G  G +G  GR G  
Sbjct: 1261 GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1320

Query: 358  GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ----KGSMGD 413
            G  G  G PGVPG  GM G  G  G  G  G  G  GPPG PG+ G  GQ    KG  G 
Sbjct: 1321 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP 1380

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGE 473
            PG+PG  GL+G  G +GP G  GP G  G  G +GLPG        G  G KG+ G  G+
Sbjct: 1381 PGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF------DGAGGRKGDPGLPGQ 1434

Query: 474  LGPKGTQGPNGTSGVQGVPGPPGPLGLQGV 503
             G +G  GP G  G+Q   GPPGP G   V
Sbjct: 1435 PGTRGLDGPPGPDGLQ---GPPGPPGTSSV 1461



 Score =  340 bits (872), Expect = 3e-93
 Identities = 201/427 (47%), Positives = 229/427 (53%), Gaps = 42/427 (9%)

Query: 24   GAQRVGLPGPPGP---PGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPG 80
            G   +GLPG PGP   PG PG PG  GI G  G PGLPG PG  GA G+PG PG  G PG
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 81   LPGVDGLTGRDGPPGPKGAPGE---RGSLGPPGPPGLGGK----GLPGPPGEAGV----- 128
             PG  G++G  G PG  G PG     G  G PGPPG  GK    G+PGP G+ G      
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 129  ---SGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGP 185
                GPPG  GL G  G  GLPG+PG PG PGP G PG    G   +Q     PPGPPG 
Sbjct: 1189 FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF--HGFPGVQ----GPPGPPGS 1242

Query: 186  PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGD 245
            PG P  +GP G  G QG  G+ G +G PGP GP GLPG+ G++G +G  G PG  G PG 
Sbjct: 1243 PG-PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301

Query: 246  RGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGK 305
            +G    +GPPG+ G PG+ G  G +G  G  G  G  G  GP G PG AGP GEPG+ G 
Sbjct: 1302 KGD---QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1358

Query: 306  DGQNGVPGLDGQ----KGEAGRNGAPGEKGPNGLP------GLPGRAGSKGEKGERGRAG 355
             G  G+PG  GQ    KG+AG  G PG+ G  GLP      GLPG  G  G+ G  G  G
Sbjct: 1359 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1418

Query: 356  ELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV-RGFQGQKGSMGDP 414
              G  G  G+PG+P   G PG RG  G  G  G  GP GPPG   V  GF   + S    
Sbjct: 1419 FDGAGGRKGDPGLP---GQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTD 1475

Query: 415  GLPGPQG 421
                PQG
Sbjct: 1476 APQCPQG 1482



 Score =  336 bits (861), Expect = 5e-92
 Identities = 223/545 (40%), Positives = 257/545 (47%), Gaps = 86/545 (15%)

Query: 180 PGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGP 239
           PG  G PG+PGF GP G  G +G+ G DG    PGPPGP G+      +GP GL G PG 
Sbjct: 53  PGLEGHPGLPGFPGPEGPPGPRGQKGDDGI---PGPPGPKGI------RGPPGLPGFPGT 103

Query: 240 LGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGF---RGPKGDLGRPGPKGTPG---- 292
            G PG  G  G  GP GIPG  G  G+RG  G  GF   +GP G  G PG KG PG    
Sbjct: 104 PGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIM 163

Query: 293 --VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE--K 348
             + GP G PG PG  G  G+PG  G  G  G  G PG  GP G PGLPG  G+ G   +
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 349 GERGRAGELGEAGPSGEPGVPGDAGMP-------GERGEAGHRGSAGALGPQGPPGAPGV 401
           G +G  GE G  GP G PG   +   P       G++G  G RG  G  G +GPPG PG 
Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG- 282

Query: 402 RGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG- 460
            G +G+KG  G+PG  G  G  G+ G  G  G  G  G  G  G DG  G KG+ GP G 
Sbjct: 283 -GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341

Query: 461 --LVGPK-------GESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLG--LQGVPGVPGI 509
             LV P+       GE G+ G  G  G +G  G  G+QG PG PGP G  + G PG PG 
Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401

Query: 510 TGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPG 569
            G+ G  G E                              P  I  PGP G  G PG PG
Sbjct: 402 PGERGQKGDEG-----------------------------PPGISIPGPPGLDGQPGAPG 432

Query: 570 SIGHPGARGP----------PGYRGPTGELGDPGPRGNQGDRGDKG-----AAGAGLDGP 614
             G PG  GP          PG  GP G  GD G +G QG +GDKG       G G+ GP
Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 615 EGDQGPQGPQGVPGT-SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLG 673
            G  G  G  G PG+    GQ G  G+ G  G  GLPG  GA G PG   +    G +L 
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 674 GVGEK 678
             G K
Sbjct: 553 FPGMK 557



 Score =  285 bits (729), Expect = 1e-76
 Identities = 159/341 (46%), Positives = 188/341 (55%), Gaps = 30/341 (8%)

Query: 15   LLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP--GPPGPKGAPGKPGK 72
            L GE     G    G PGPPG  G PG+ G  G  G+ G PG P  G PGP G PG  G+
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203

Query: 73   PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPP 132
             G+ GLPG+PG  GL G  G PG  G PG +   GPPGPPG  G  L GP G  G  GPP
Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ---GPPGPPGSPGPALEGPKGNPGPQGPP 1260

Query: 133  GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192
            G  G +G PGP G PGLPG  G  G  G+PG                PG PG PG+ G +
Sbjct: 1261 GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPG---------------QPGLPGLPGLKGDQ 1305

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252
            GP G +G  G  G +G KGDPG P   G+PG  G++GP    G+PG  GP G+ G IG  
Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLP---GVPGFPGMKGP---SGVPGSAGPEGEPGLIGPP 1359

Query: 253  GPPGIPGAPGKA-GDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
            GPPG+PG  G++   +G+ GP G  G  G  G PGP+G  G+ GP+G PG PG+   NG+
Sbjct: 1360 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR---NGL 1416

Query: 312  PGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG 352
            PG DG  G  G  G PG+ G  GL G PG  G +G  G  G
Sbjct: 1417 PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  535 bits (1377), Expect = e-152
 Identities = 330/717 (46%), Positives = 368/717 (51%), Gaps = 92/717 (12%)

Query: 24   GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPG---PKGAPGKPGKPGEAGLPG 80
            G   +G PG  G PG  G PGQDG+ G  G PG  GP G   PKGA G PG+PGE GLPG
Sbjct: 430  GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 489

Query: 81   LPGVDGLTGRDGPPG---PKGAPGERGSLGPPGPPGLGGK----GLPGP------PGEAG 127
              G+ G  G  GP G   P GAPGE G  GPPGP G  G+    G PGP      PG+AG
Sbjct: 490  ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549

Query: 128  VSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL----PEGATDLQCPSICPPGPP 183
              G PG  GLRG PG  G  G  GPPGP GP G  G      P G   L       PGPP
Sbjct: 550  EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL-------PGPP 602

Query: 184  GPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPP 243
            GPPG  G  G  G  GE G  G  G +G+ G PG  G PG+ GLQGPRGL G PG  GP 
Sbjct: 603  GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 662

Query: 244  GDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGD---LGRPGPKGTPG------VA 294
            G  GP G   PPG  G PG  G  GERG  G  GPKGD   +G  GP+G PG      + 
Sbjct: 663  GASGPAG---PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 719

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRA 354
            GP G PG  G +G+ G  G  G  G AG  GAPGE+G  G PG  G AG  G  G+ G  
Sbjct: 720  GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779

Query: 355  GELGEAGPSGEPGVPGD---AGMPGERGEAGHRGSAGALGPQGPPGA---PGVRGFQGQK 408
            GE GEAG  G+ G PG    +G PG +G  G  G  GA G QGPPGA   PG  G  G  
Sbjct: 780  GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839

Query: 409  GSMGDPGLPGP------QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLV 462
            GS G+PG PGP       G +G  GD GP G AG  G QG AG  G  G+ G+ GPSG  
Sbjct: 840  GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 899

Query: 463  GPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGV------------PGIT 510
            GP G  G  G+ G  G  G  G  G  G+PGP G  G QG PG             PG+T
Sbjct: 900  GPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 959

Query: 511  GKPGVPGKEASEQRI----RELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPG--- 563
            G  G PG+E S        R+   G+  ++    A  +  P APG  G PGPAGP G   
Sbjct: 960  GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGA--VGAPGAPGPPGSPGPAGPTGKQG 1017

Query: 564  ---------PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDG 613
                     P GP G  G  G +GP G RG  GE G+PG RG +G RG  G  G  G  G
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1077

Query: 614  PEGDQG------PQGPQGVPG----TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            P GDQG      P GP+G PG    + KDG +G PG  GPPG  G  G  G  G PG
Sbjct: 1078 PSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1134



 Score =  525 bits (1353), Expect = e-149
 Identities = 326/723 (45%), Positives = 361/723 (49%), Gaps = 94/723 (13%)

Query: 10  LLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK 69
           +LL LL+  +L   G Q V  PGP G  G PG      I    GP G PGP GP G  G 
Sbjct: 11  VLLTLLVAAVLRCQG-QDVRQPGPKGQKGEPG-----DIKDIVGPKGPPGPQGPAGEQGP 64

Query: 70  PGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK------------ 117
            G  G+ G  G PG     GRDG PG  G PG  G  GPPGPPGLGG             
Sbjct: 65  RGDRGDKGEKGAPGP---RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEK 121

Query: 118 ----------------GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGH 161
                           G  GPPG AG  GP G  G  G PG  G+ G  GP GPPGPPG 
Sbjct: 122 AGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK 181

Query: 162 PGVLPEGATDLQCPSICPPGP------PGPPGMPGFKGPTGY------KGE------QGE 203
           PG   E     +     PPGP      PG PG+PG KG  GY      KGE      +GE
Sbjct: 182 PGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE 241

Query: 204 VGKDGEKGDPGPPGPAGLPGSVGLQGP------RGLRGLPGPLGPPGDRGPIGFRGPPGI 257
            G  GE G PGP GP GLPG  G  GP      RG  G PGP GPPG  GP G  G PG 
Sbjct: 242 SGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 301

Query: 258 PGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQ 317
           PGA G+AG  G RGPEG +GP+G+       GTPG  GP+G  G PG DG  G  G  G 
Sbjct: 302 PGAKGEAGPTGARGPEGAQGPRGE------PGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355

Query: 318 KGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMP-- 375
            G AG  G PG +GP G  G  G  G KG+ GE G AG  GE GP GEPG  G  G P  
Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 415

Query: 376 -GERGEAGHRGSAGALGPQGPP---GAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGP 431
            GE G+ G RG  G +GP GPP   GAPG RGF GQ G  G  G PG +G  G  G +G 
Sbjct: 416 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 475

Query: 432 GGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGV 491
            G  G  G+ G+ G+ GL G  G+ GP G VGP G  G  G  GP G QG  G  GV G 
Sbjct: 476 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 535

Query: 492 PGP------PGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLR 545
           PGP      PG  G +G+PG PG+ G PG  G+  +         G   E+  Q A    
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP--AGPAGERGEQGA---- 589

Query: 546 KPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKG 605
            P   G  G PGP GPPG  G PG  G PG  G PG  GP GE G PG RG+ G +G +G
Sbjct: 590 -PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 648

Query: 606 AAG----AGLDGPEGDQGPQGP---QGVPG-TSKDGQDGAPGEPGPPGDPGLPGAIGAQG 657
             G     G DGP+G  GP GP   QG PG     G+ GA G  GP GD G  G  G +G
Sbjct: 649 PRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG 708

Query: 658 TPG 660
            PG
Sbjct: 709 APG 711



 Score =  509 bits (1310), Expect = e-144
 Identities = 346/841 (41%), Positives = 387/841 (46%), Gaps = 197/841 (23%)

Query: 22   AAGAQ-RVGLPGPPGPPGP------PGKPGQDGIDGEAGPPGLPGPPG---PKGAPGKPG 71
            AAGA+   G PGP GPPGP      PG PG  G  GEAGP G  GP G   P+G PG PG
Sbjct: 271  AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330

Query: 72   KPGEAGLPGLPGVDGLTGRDGP------------PGPKGAPGERGSLGPPGP------PG 113
             PG AG  G PG DG+ G  G             PGP+G PG +G+ GP GP      PG
Sbjct: 331  SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390

Query: 114  LGG-------KGLPGPPGEAGVSGP------------PGGIGLRGPPGPSGLPG---LPG 151
            + G       KG PGP G  G  GP            PGG+G  GPPG  G PG    PG
Sbjct: 391  IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 450

Query: 152  PPGPPGPPGHPGVLPEGATDLQCPSIC--PPGPPGPPGMPGFKGPTGYKGEQGEVGK--- 206
              G  GP G PG    G + L  P      PG PG PG+PG +G TG  G+ G  GK   
Sbjct: 451  QDGLAGPKGAPG--ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 508

Query: 207  ---DGEKGDPGPPGPAGL---PGSVGLQGPRG------------------LRGLPGP--- 239
                GE G PGPPGP G    PG +G  GP+G                  LRGLPG    
Sbjct: 509  SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568

Query: 240  ---LGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGP 296
                GPPG  GP G RG  G PG  G  G  G  GP G  G  GD G PG  G PG+ GP
Sbjct: 569  TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 628

Query: 297  SGEPGMPGKDGQ------------NGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGS 344
             GE G PG+ G              G PG DG KG +G  G PG +GP GL G+PG  G+
Sbjct: 629  RGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGA 688

Query: 345  KGEKGERGRAGELGEAGPSGEPGVPGDAGM------------------------------ 374
             G  G +G  G++GE GP G PG  G  G+                              
Sbjct: 689  AGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGA 748

Query: 375  ---PGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGP 431
               PGERGE G  G AG  GP G  G PG +G QG+ G  GD G PGPQG  G  G +GP
Sbjct: 749  RGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGP 808

Query: 432  GGAAGPKGDQGI------------------AGSDGLPGDKGELGPSGLVGPK---GESGS 470
             G  GPKG +G                    GS+G PG  G  GPSG  GPK   G+SG 
Sbjct: 809  TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 868

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPG--KEASEQRIREL 528
             G  G  G QGP G  G +G PG  GP G +G PG  G+ G+ G+ G   +  E+    L
Sbjct: 869  PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 928

Query: 529  CG--GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPP---GPPGPPGSIGHPGARGPPGY- 582
             G  G   +Q A        P A G  G PGP GPP   GP G PG  G PGA GPPG  
Sbjct: 929  PGPSGEPGKQGA--------PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRD 980

Query: 583  --------RGPTGELGDP------------GPRGNQGDRGDKGAAG-AGLDGPEGDQGPQ 621
                    RG TG +G P            GP G QGDRG+ GA G  G  GP G +G Q
Sbjct: 981  GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1040

Query: 622  GPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGS 681
            GPQG       G  G  GEPG  G  G  G  G QG PG    S  QGA   G    SG 
Sbjct: 1041 GPQG-----PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGA--SGPAGPSGP 1093

Query: 682  R 682
            R
Sbjct: 1094 R 1094



 Score =  487 bits (1253), Expect = e-137
 Identities = 299/667 (44%), Positives = 337/667 (50%), Gaps = 93/667 (13%)

Query: 23   AGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLP 82
            AG Q  G  GP G PG  G+PG  G  G  G PG+ G PGPKGA G+PGK GE GLPG P
Sbjct: 500  AGPQ--GKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 557

Query: 83   GVDGLTGRDG------PPGPKGAPGERGSLG------------PPGPPGLGGK-GLPGPP 123
            G+ GL G+DG      PPGP G  GERG  G            PPGPPG GGK G  G P
Sbjct: 558  GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 617

Query: 124  GEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGP 182
            GEAG  G  G  G RG PG  G PG  G  GP G PG PG   P+GA+        P GP
Sbjct: 618  GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG-------PAGP 670

Query: 183  PGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGP 242
            PG  G PG +G  G +G  G  G  G++GD G  GP G PG  G +G  G  G PGP G 
Sbjct: 671  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730

Query: 243  PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEG---FRGPKGDLGRPGPKGTPGVAGPSGE 299
             G++G +G  GP G  GA G  G+RGE GP G   F GP G  G+PG KG  G AG  G+
Sbjct: 731  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 790

Query: 300  PGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGP------------------NGLPGLPGR 341
             G PG  G +G PG  G  G  G  GA G +GP                  NG PG PG 
Sbjct: 791  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850

Query: 342  AGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV 401
             G  G+ G +G  G+ G  G +GEPG+ G AG PGE+GE G  G +GA GP GP G  G 
Sbjct: 851  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910

Query: 402  RGF---QGQKGSMGDPGLPGP------QGLRGDVGDRGPGGAAGPKG---------DQGI 443
            RG     GQ+G  G PGLPGP      QG  G  GDRGP G  GP G          +G 
Sbjct: 911  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970

Query: 444  AGSDGLPG---------DKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGP 494
             G+DG PG         D+GE G  G  G  G  GS G  GP G QG  G +G QG  GP
Sbjct: 971  PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030

Query: 495  PGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIG 554
             GP G +G+ G  G  G  G    EA E   R L G      +  L      P   G  G
Sbjct: 1031 SGPAGARGIQGPQGPRGDKG----EAGEPGERGLKGHRGFTGLQGLPG---PPGPSGDQG 1083

Query: 555  RPGPAGPPGPPGPPGSIGH---------PGARGPPGYRGPTGELGDPGPRGNQGDRGDKG 605
              GPAGP GP GPPG +G          PG  GPPG RG +GE G  GP GN G  G  G
Sbjct: 1084 ASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1143

Query: 606  AAGAGLD 612
              G G+D
Sbjct: 1144 PPGPGID 1150



 Score =  461 bits (1186), Expect = e-129
 Identities = 279/625 (44%), Positives = 317/625 (50%), Gaps = 88/625 (14%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP------PGPKGAPGKPGKPGEAGLPGLP 82
            GLPGPPGPPG  GKPG  G+ GEAG PGL GP      PG +G+PG  G  G  GLPG P
Sbjct: 597  GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 656

Query: 83   GVDGLTGRDGPPGPKGA---------PGERGSLGPPGPPG-LGGKGLPGPPGEAGVSGPP 132
            G DG  G  GP GP GA         PGERG+ G  GP G  G  G  GP G  G  G  
Sbjct: 657  GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 716

Query: 133  GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192
            G  G  GPPGP+G  G  G  GPPGP G  G    GA   +     PPGP G  G PG  
Sbjct: 717  GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGA--RGAPG-ERGETGPPGPAGFAGPPGAD 773

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS---VGLQGPRGLRGLPGPLGPPGDRGPI 249
            G  G KGEQGE G+ G+ G PGP GP+G PG     G+ GP+G RG  GP G  G  G  
Sbjct: 774  GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 833

Query: 250  GFRGPPGI---PGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKD 306
            G  GPPG    PG PG  G  G+ GP+G RG  G  GR G  G  G AGP GE G PG D
Sbjct: 834  GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 893

Query: 307  GQNGVPGLDGQKGEAGRNGA---PGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPS 363
            G +G  G  G +G AG+ G    PG++G  G PGLPG +G  G++G  G +G+ G  GP 
Sbjct: 894  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953

Query: 364  GEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGP---- 419
            G PG+ G AG PG  G      S GA GP G  GA GV+G +G+ G++G PG PGP    
Sbjct: 954  GPPGLTGPAGEPGREG------SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1007

Query: 420  --------QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR 471
                    QG RG+ G +GP G +GP G +GI G  G  GDKGE G  G  G KG  G  
Sbjct: 1008 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1067

Query: 472  G------ELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRI 525
            G        GP G QG +G +G  G  GPPGP+G  G  G  GI G  G PG        
Sbjct: 1068 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR------ 1121

Query: 526  RELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGP 585
                                     G  G  GPAGPPG PGPPG    PG  GP      
Sbjct: 1122 -------------------------GRSGETGPAGPPGNPGPPGP---PGPPGPGIDMSA 1153

Query: 586  TGELG--DPGPRGNQGDRGDKGAAG 608
               LG  + GP   Q  R D+ A G
Sbjct: 1154 FAGLGPREKGPDPLQYMRADQAAGG 1178



 Score =  397 bits (1019), Expect = e-110
 Identities = 228/516 (44%), Positives = 259/516 (50%), Gaps = 61/516 (11%)

Query: 4    PRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQD---GIDGEAGPP----- 55
            P A  P  L  + GE  AA  A   G  G  G  GP G PG+D   G+ G  GPP     
Sbjct: 671  PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730

Query: 56   -------GLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGP 108
                   G PGP G  GA G PG+ GE G PG  G  G  G DG PG KG  GE G  G 
Sbjct: 731  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 790

Query: 109  PGPPG-LGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPE 167
             G PG  G  G PGP G  GV+GP G  G +GPPG +G PG  G  GPPG  G+      
Sbjct: 791  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN------ 844

Query: 168  GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL 227
                        PGPPGPPG  G  GP G +G+ G  G+ GE G  GP GP G  G  G 
Sbjct: 845  ------------PGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 892

Query: 228  QGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP 287
             GP G  G PGP G  G RG +G  G  G  G PG  G  GE G +G  G  GD G PGP
Sbjct: 893  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952

Query: 288  KGTPGVAGPSGEPGMPGKDGQNGVPGLD------GQKGEAGRNGAPGEKGPNGLPGLPGR 341
             G PG+ GP+GEPG  G  G +G PG D      G +GE G  GAPG  GP G PG  G 
Sbjct: 953  VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012

Query: 342  AGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV 401
             G +G++GE G  G +G +GP+G  G+ G  G  G++GEAG                PG 
Sbjct: 1013 TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE---------------PGE 1057

Query: 402  RGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGL 461
            RG +G +G  G  GLPGP G  GD G  GP G +GP+G  G  G  G  G  G  GP G 
Sbjct: 1058 RGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP 1117

Query: 462  VGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGP 497
             GP+G SG  G  GP G  GP       G PGPPGP
Sbjct: 1118 PGPRGRSGETGPAGPPGNPGP------PGPPGPPGP 1147



 Score =  182 bits (461), Expect = 1e-45
 Identities = 115/310 (37%), Positives = 136/310 (43%), Gaps = 41/310 (13%)

Query: 371 DAGMPGERGEAGHRGSA-GALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDR 429
           D   PG +G+ G  G     +GP+GPPG  G  G QG +G  GD G  G  G RG  G+ 
Sbjct: 27  DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86

Query: 430 GPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGES------GSRGELGPKGTQGPN 483
           G  G  GP G  G  G  GL G+       G     G +      G  G +GP+G  GP 
Sbjct: 87  GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146

Query: 484 GTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAH 543
           G  G QG  G PG  G  GV G  G  G PG PGK   +                     
Sbjct: 147 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDD--------------------- 185

Query: 544 LRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGD 603
                  G  G+PG AG  GPPGP G+ G PG  G PG +G  G  G  G +G  G  G 
Sbjct: 186 -------GEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 238

Query: 604 KGAAGAGLDGPEGDQGPQGPQGVPG----TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTP 659
           KG +G+   G  G  GP GP+G+PG    T   G  GA G  G PG  G PG +G  G P
Sbjct: 239 KGESGS--PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 296

Query: 660 GICDTSACQG 669
           G       +G
Sbjct: 297 GFPGAPGAKG 306



 Score =  141 bits (355), Expect = 2e-33
 Identities = 96/256 (37%), Positives = 113/256 (44%), Gaps = 80/256 (31%)

Query: 463 GPKGESGSRGEL----GPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK 518
           GPKG+ G  G++    GPKG  GP G +G QG  G  G  G +G PG  G  G+PG P  
Sbjct: 32  GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP-- 89

Query: 519 EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGH----- 573
                                              G PGP GPPGPPGPPG  G+     
Sbjct: 90  -----------------------------------GNPGPPGPPGPPGPPGLGGNFAAQM 114

Query: 574 ----------------PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGD 617
                            G  GP G RGP G  G PGP+G QG+ G+ G  G  + GP G 
Sbjct: 115 AGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG--VSGPMGP 172

Query: 618 QGPQGPQGVPGTSKDGQDGAPGE------PGP------PGDPGLPGAIGAQGTPGICDTS 665
           +GP GP G PG   DG+ G PG+      PGP      PG PGLPG  G +G PG+    
Sbjct: 173 RGPPGPPGKPGD--DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAK 230

Query: 666 ACQGAVLGGVGEKSGS 681
              GA   GV  +SGS
Sbjct: 231 GEAGA--PGVKGESGS 244


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  535 bits (1377), Expect = e-152
 Identities = 332/711 (46%), Positives = 370/711 (52%), Gaps = 87/711 (12%)

Query: 29   GLPG---PPGPPG--PPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK----PGKPGEAGLP 79
            GLPG   P GPPG  PPG  G+ GI G AG PG PG PGPKG PG+    PGKPG  G P
Sbjct: 612  GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 80   GLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGG----- 134
            G  G  GL G  G PG  G PG  GS G PG PG+G  G PGP G  G+ GPPG      
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 135  -IGLRGPPGPSGLPG--------LPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGPPG 184
             IGL GPPGP G PG        LPGPPGPPG PG  G L P+G           PGPPG
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF-------PGPPG 784

Query: 185  PPGMPGFKGPTGYKGEQGEVGKDGEKGDPG--------PPGPAGLPGSVGLQGPRGLRGL 236
            PPG  G  G  G KG+ G  G+ G  G PG        PPGP G+PG +G  G  G+ G 
Sbjct: 785  PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 237  PGPLGPPG--DRGPIGFRGPPGIPGAPGKAGDRG------ERGPEGFRGPKGDLGRPGPK 288
             G  GPPG    GP G RG PGIPGAPG  G  G      + G  GF G KG++G  GP 
Sbjct: 845  KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPP 904

Query: 289  GTPG---VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G PG   + G SG PG+ G DG  G PGL G  GE G  G PG  GP G P  P   GSK
Sbjct: 905  GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG-PMDPNLLGSK 963

Query: 346  GEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQ 405
            GEKGE G  G  G +GP G  G+PGD G PG  G+ G  G  G  G  G PG PG+ G  
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 406  GQKGSMGDPGLPGPQGLRGDVGDRG-------PG--GAAGPKGDQGIA--GSDGLPGDKG 454
            G KG++GD G PGPQG+ G  G  G       PG  G  G KGD GI+  G  GLPG KG
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083

Query: 455  ELGPSGLVGPKGESGSRGELG------PKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPG 508
            E G  G  G  G  GS G+ G        G +G  G  G  G PGPPGP G+ G PG PG
Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143

Query: 509  ITGKPGVPGK--EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPG 566
            + G+PG  G      +       G    + I   A    +P  PG  G PGP G PG  G
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSG 1202

Query: 567  PPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGV 626
              G  G PG  G PG  GP GE G  G  G QG  G  G+ G  L+GP+G+ GPQGP G 
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262

Query: 627  PGTS-------KDGQDGAPGE---------PGPPGDPGLPGAIGAQGTPGI 661
            PG +        +G  G PG          PG PG PGLPG  G QG PG+
Sbjct: 1263 PGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1313



 Score =  533 bits (1374), Expect = e-151
 Identities = 323/736 (43%), Positives = 364/736 (49%), Gaps = 107/736 (14%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP--------PGPKGAPGKPG------KPG 74
            G PG PGPPG PG PG+ G++G  GPPG PGP        PGP G PG PG        G
Sbjct: 716  GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 75   EAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGP--- 131
            + G PG PG  G TG DG PGPKG  G  G  GP GPPGL G G+ GPPG  G+ GP   
Sbjct: 776  DRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 132  --------------PGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGA-------T 170
                          P G+ + GPPG  G PG+PG PGP GPPG PG LP  A       T
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG-LPGKAGASGFPGT 894

Query: 171  DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQ------------GEVGKDGEKGDPGPPGP 218
              +   + PPGPPGP G+PG  G  G KG+             GE G  GE G PGPPGP
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 219  --------------AGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA 264
                           GLPG  G+ GP+G +GLPG  G PG  G  G  GPPG  G PG  
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 265  GDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDG--------------QNG 310
            G  G  GP G +G  GD+G PGP+G  G  GPSG PG PG  G                G
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 311  VPGLDGQKGEAGRNGAPGEK------GPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSG 364
            +PGL G KGE G  G PG        G  GLPGLPG  G+KG+ G  G  G  G  GP G
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134

Query: 365  EPGVPGDAGMPGERGE---AGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL--PGP 419
              G PG+ G+PGE G     GH G  G  G +G PG  G+ G  GQKG  G PG   PGP
Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 420  QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE-----SGSRGEL 474
             GL G  G +G GG  G  G+ G+ G  G PG  G  G  G  GP G       G +G  
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254

Query: 475  GPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SEQRIRELC 529
            GP+G  G  G +G QG+PGP GP GL G  G+ G  G PG PG         +Q    L 
Sbjct: 1255 GPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ 1314

Query: 530  GGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGE- 588
            G      +  +      P  PG  G  GP+G PG  GP G  G  G  GPPG  GP+G+ 
Sbjct: 1315 GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQS 1374

Query: 589  ---LGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGPP 644
                GD GP G  G  G KG  G    GP+G  GP GP G PG     G DGA G  G P
Sbjct: 1375 IIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1432

Query: 645  GDPGLPGAIGAQGTPG 660
            G PG PG  G  G PG
Sbjct: 1433 GLPGQPGTRGLDGPPG 1448



 Score =  522 bits (1344), Expect = e-148
 Identities = 319/728 (43%), Positives = 369/728 (50%), Gaps = 110/728 (15%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAG---PPGLPGPPGPKGAPGKPGK------------- 72
            GLPG PGPPG  G PGQ G  G+AG   P GLPG PG  GAPG PG              
Sbjct: 497  GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 73   ---------PGEAGLPGLPGVDGLTGRDGPPGPKGAPGE---RGSLGPPGPPGLGGK--- 117
                     PG  GLPGLPG  G  G  G PGPKG PG    +G  GPPG PGL G    
Sbjct: 557  KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616

Query: 118  ---------GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPG-------------------- 148
                     G PGP GE G+ G  G  G  G PGP G PG                    
Sbjct: 617  IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 676

Query: 149  --LPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGK 206
              LPG PG PG PG PG+ P    +   P I  PGPPGP G PG  GP G  G  G +G 
Sbjct: 677  VGLPGDPGLPGQPGLPGI-PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 207  DGEKGDPGPPGPAGLPGSV--GLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA 264
            +G  G PG PGP G PG    G  GP GL G  G LGP GDRG  G  GPPG  G  G  
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 265  GDRGERGPEGFRGPKGDLGRPG-----PKGTPGVAGPSGEPGM---PGKDGQNGVPGLD- 315
            G +G+ GP G  GP G  G PG     P G PG+ GP G+PG+   PG+ G  G PGLD 
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 316  ----GQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGD 371
                G++G  G  GAPG  GP G PGLPG+AG+ G  G +G  G +G  GP G  G+PG 
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 372  AGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGP 431
            +G+PG +G+ G +G  G  GP G  G+ G  G  G  G M DP L G +G +G+ G  G 
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM-DPNLLGSKGEKGEPGLPGI 974

Query: 432  GGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGE---LGP---KGTQGPNGT 485
             G +GPKG QG+ G  G PG  G+ G  G  GPKG  G  G+   +GP   KGT G  G 
Sbjct: 975  PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGF 1034

Query: 486  SGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLR 545
             G QGV GPPGP G+ G PG PG+ G+ G  G             G+ S  +  L     
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP-----------GISSIGLPGLPGPKG 1083

Query: 546  KPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKG 605
            +P  PG  G PG  G  G PG PG  G PGA+G PG  G  G  G PGP+G  G  G+ G
Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143

Query: 606  AAGA----------GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPG--PPGDPGLPGAI 653
              G           G  GP G++G  G  G+PG +  GQ G PG+PG   PG PGLPG  
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA--GQKGEPGQPGFGNPGPPGLPGLS 1201

Query: 654  GAQGTPGI 661
            G +G  G+
Sbjct: 1202 GQKGDGGL 1209



 Score =  508 bits (1308), Expect = e-144
 Identities = 327/817 (40%), Positives = 381/817 (46%), Gaps = 186/817 (22%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPG---PK-------------GAPGKPGK 72
            G+PG PG PG PG+PG+DG  G+ G  G PGPPG   P+             G PG PG+
Sbjct: 310  GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 73   PGEAGLPGLPGVDGLTGRDG-----PPGPKGAPGERGSLGPPGPPGL------------G 115
             GE G PG+ G  GL G  G     PPGP G PGERG  G  GPPG+            G
Sbjct: 370  KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429

Query: 116  GKGLPGPPG-------------EAGVSGPPG-------------------------GIGL 137
              GLPGPPG             E G  GPPG                         G G+
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 138  RGPPGPSGLPGLPGPPGPPGPPGHPGVLPE-GATDLQCPSICPPGPPGPPGMPGFKGPTG 196
             GPPG  GLPGLPGPPG  G PG  G   + GAT        P G PG PG PG  G  G
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATG-------PKGLPGIPGAPGAPGFPG 542

Query: 197  YKGEQGEV----GKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252
             KGE G++    G  G+KG+ G PG  GLPG  G  G  GL GLPGP G PG     G R
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 253  GPPGIPGAPGKAGDRGERGPEGFR-----------------------GPKGDLG------ 283
            GPPG PG PG  G+ G  GP GF                        GPKGD G      
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 284  -RPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGA--PGEKGPNGLPGLPG 340
             +PG  G PG  G  G PG PG  GQ G+PG+ G KGE G  G   PG  GP G PG+PG
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722

Query: 341  RAGSKGEKGE---RGRAGELGEAGPSGEPGV-----PGDAGMPGERGEAGHRGSAGALGP 392
              G+ G  G     G  G  G  GP GEPG      PG  G+PG +G  G +G  G  GP
Sbjct: 723  PPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782

Query: 393  QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG--DVGDRGPGGAAGPKGDQGIAGSDGLP 450
             GPPG  G+ G  G KG +G  G PGP G  G   +G +GP G  G  G  G  G  G+P
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 451  GDKGELGPSGL--------------------VGPKGESGSRGELGPKGTQGPNGTSGVQG 490
            G+KG+ GP GL                    +GP G  G  G+ G  G  G  G  G+ G
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 491  VPGPPGPLG---------------LQGVPGVPGITGK------PGVPGK----------- 518
             PGPPGPLG               LQG PG+PG TG+      PG+PG            
Sbjct: 903  PPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGS 962

Query: 519  --EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGA 576
              E  E  +  + G    +    L      P  PG  G+PG  GPPGP G PG  G PG 
Sbjct: 963  KGEKGEPGLPGIPGVSGPKGYQGLPGD---PGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 577  RGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA----GLDGPEGDQGPQGPQGVPGTSKD 632
             GPPG +G  G++G PGP+G +G  G  G  G     GL G +GD+G  G   +      
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLP 1079

Query: 633  GQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG 669
            G  G PG PG PG+PG+ G++G  G PG+  T   +G
Sbjct: 1080 GPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116



 Score =  502 bits (1293), Expect = e-142
 Identities = 336/794 (42%), Positives = 382/794 (48%), Gaps = 166/794 (20%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
           GLPG PGP GPPG  GQ G DG  GPPG   P G +G PG PG PG  GLPG+PG DG  
Sbjct: 60  GLPGFPGPEGPPGPRGQKGDDGIPGPPG---PKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 89  GRDGPPGPKGAPGER---------GSLGPPGPPGLGG----------KGLPGPPGEAGVS 129
           G  G PG  G  GER         G  GPPGPPG+ G            LPGP G  G  
Sbjct: 117 GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176

Query: 130 GPPGGIGLRGP---PGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPS--------IC 178
           GPPG  GL GP   PGP G PG PG  GPPGPPG PG       + Q P           
Sbjct: 177 GPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG 236

Query: 179 PPGPP-------------------------GPPGMPGFKGP-------TGYKGEQGE--- 203
           PPGPP                         GPPG PG +GP        G KGEQGE   
Sbjct: 237 PPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 204 ---VGKDGEKGD---PGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGP-------IG 250
               GKDGE G    PG PG  G PG  G  G +G +G  GP GPPG   P       IG
Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIG 356

Query: 251 FRGPPGIPGAPGKAGDR---GERGPEGFRGPKGD--LGRPGPKGTPGVAGPSGE------ 299
            +G  G+PG PG+ G+R   G +GP G  GP G   +G PGP G PG  G  G+      
Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI 416

Query: 300 --PGMPGKDGQNGVPGLDGQKGEAGRNGAPG----EKGPNGLPGLPGRAGSKGEKGERGR 353
             PG PG DGQ G PGL G  G AG +  P     E GP G PG PG  G +GE+G +G 
Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGD 476

Query: 354 AGE-------LGEAGPSGEPGVPGDAGMPGE---RGEAGHRGSAGALGPQGPPGAPGVRG 403
            G+        G +GP G+PG+PG  G PG     G+ G +G AGA GP+G PG PG  G
Sbjct: 477 KGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536

Query: 404 FQGQKGSMGDPG--LPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPG---------- 451
             G  GS G+PG  L  P G++GD G+ G  GA G  G  G  G DGLPG          
Sbjct: 537 APGFPGSKGEPGDILTFP-GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 452 --DKGELGPSGLVGPKGESGSRGELGPK--GTQGPNGTSGVQGVPGPPGPLGLQGVPGVP 507
              KGE GP G  G  G  G+ G +GP   G  GP G  G+QGV G PG  G+ G  G P
Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655

Query: 508 GIT----GKPGVPGKEASEQRI----------RELCGGMISEQIAQLAAHLRKPLAPGSI 553
           G T    GKPG+PG    +  +          +    G+   +       +  P  PG  
Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPK 715

Query: 554 GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGE-----LGDPGP------RGNQGDRG 602
           G PG  GPPG PG PG IG  G  GPPG+ GP GE      G PGP      +G  G +G
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 603 DKGAAG-------AGLD---------GPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD 646
           D+G  G        GLD         GP G  GP GP G+PG    G  G PG PGP G 
Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 647 PGLPGAIGAQGTPG 660
           PGL G  G +G PG
Sbjct: 836 PGLHGIPGEKGDPG 849



 Score =  470 bits (1209), Expect = e-132
 Identities = 296/681 (43%), Positives = 336/681 (49%), Gaps = 119/681 (17%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPG-----LPGPPGPKGAPGKPGKPGEAGLPGLPG 83
            G PGPPG PGP G+PG  GI GE G PG     +PGPPG +G+PG PG PG  G PG PG
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 84   VDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK-GLPGPPGEAGVSGPPGGIGLRGPPG 142
            + G  G  G PG KG  G  G  GPPGP G+ G+ G+PG  G+ G+ G PG  G  G  G
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 143  PSGLPGLPGPPGP--------------PGPPGHPGVL-PEGATDLQCPSICP-------- 179
              G PGLPGPPGP              PG PG PGV  P+G   L      P        
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 180  PGPPGP------PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG---SVGLQGP 230
            PGPPGP      PG PG  GP G KG  G++G  G +G  GPPGP+G+PG   S GL G 
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 231  RGLRGLPG--PLGPPGDRGPIGFRGPPGIPGAPG---KAGDRGERGPEGFRGPKGDLGRP 285
            +G +G PG   +G PG  GP G  G PG PG PG     GD G  G  G  G KG  G P
Sbjct: 1062 KGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP 1121

Query: 286  GPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G  GTPG  GP G  G PG  G  G PG  G  G  G+ G PGEKG  G  G+PG AG K
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 346  GEKGERGRA--------GELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPG 397
            GE G+ G          G  G+ G  G PG+PG+ G+PG +GE G  G  G  GP GPPG
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241

Query: 398  APG--VRGFQGQKGSMGDPGLPGPQGLRGDVGDRGP------GGAAGPKGDQGIAGSDGL 449
            +PG  + G +G  G  G PG PGP G +G  G  GP      GG  G KG+ G  G  GL
Sbjct: 1242 SPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1301

Query: 450  PGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGI 509
            PG KG+ GP GL G  G  G  G  G  G  G  G  G++G  G PG  G +G PG+ G 
Sbjct: 1302 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1361

Query: 510  TGKPGVPGKEASEQRIRELCG--GMISEQIAQLAAHLRKPLAPGSIGRPGPAGP---PGP 564
             G PG+PG       I+   G  G+              P  PG  G PGP GP   PGP
Sbjct: 1362 PGPPGLPGPSGQSIIIKGDAGPPGI--------------PGQPGLKGLPGPQGPQGLPGP 1407

Query: 565  PGPPGSIGH---------------PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA 609
             GPPG  G                PG  G PG RG                         
Sbjct: 1408 TGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG------------------------- 1442

Query: 610  GLDGPEGDQGPQGPQGVPGTS 630
             LDGP G  G QGP G PGTS
Sbjct: 1443 -LDGPPGPDGLQGPPGPPGTS 1462



 Score =  459 bits (1180), Expect = e-129
 Identities = 296/714 (41%), Positives = 354/714 (49%), Gaps = 86/714 (12%)

Query: 10  LLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK 69
           LL L L G+   AA              G  G+ G+ G  G  G PGLPG PGP+G PG 
Sbjct: 14  LLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP 73

Query: 70  PGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVS 129
            G+ G+ G+P            GPPGPKG  G  G  G PG PGL   G+PG  G  G  
Sbjct: 74  RGQKGDDGIP------------GPPGPKGIRGPPGLPGFPGTPGL--PGMPGHDGAPGPQ 119

Query: 130 GPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICP---PGPPGPP 186
           G PG  G +G  G  G PG PG  GPPGPPG PG+  E  + +      P   PG PGPP
Sbjct: 120 GIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP 179

Query: 187 GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGL--QGPRGLRGLPGPLGPPG 244
           G+ G  GPTG  G  G  G  G  G PGPPG  G  G++GL  QGP+G +G  G  GPPG
Sbjct: 180 GIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPG 239

Query: 245 DRGPI-------------GFRGPPGIPGAPGKAGDRGERGPEGF-RGPKGDLGRPGPKGT 290
             G I             G +G PG  G PG  G RG  GP G  +G KG+ G PG +G 
Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK 299

Query: 291 PGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLP-GLPGRAGSKGEKG 349
           PG  G +G+PG+PG  G  G PG  G+ GE G+ G  G  GP GL    PG   + GEKG
Sbjct: 300 PGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKG 359

Query: 350 ERGRAGELGEAGPSGEPGVPGDAGMPGERGEA--------GHRGSAGALGPQGPPGA--P 399
             G  G  GE G  G PG+ G  G+PG  G A        G  G  G  G +GPPG   P
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 400 GVRGFQGQKGSMGDPGLPGPQGLR----GDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE 455
           G  G  GQ G+ G PG PGP G       ++ + GP G  G  GD+G+ G  G+ GDKG+
Sbjct: 420 GPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479

Query: 456 -----LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGIT 510
                +G +G+ GP G+ G  G  GP G+ G  G  G +G  G  GP GL G+PG PG  
Sbjct: 480 TCFNCIG-TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538

Query: 511 GKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP------PGP 564
           G PG  G+         + G             L  P APG  G PG  G       PGP
Sbjct: 539 GFPGSKGEPGDILTFPGMKGDK---------GELGSPGAPGLPGLPGTPGQDGLPGLPGP 589

Query: 565 PGPPGSIGHPGARGPPG------YRGPTGELGDPG--PRGNQGDRGDKGAAG----AGLD 612
            G PG I   G RGPPG        G  G +G PG  P G  G++G +G AG     G+ 
Sbjct: 590 KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIP 649

Query: 613 GPEGDQGPQ----GPQGVPGT-SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
           GP+GD G      G  G+PG   +DG  G PG+PG PG PGLPG  G++G PGI
Sbjct: 650 GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI 703



 Score =  416 bits (1068), Expect = e-116
 Identities = 250/572 (43%), Positives = 283/572 (49%), Gaps = 100/572 (17%)

Query: 28   VGLPGPPGPPGPPGKPGQDGI------DGEAGPPGLPGPPGPKGAPGKPGKPG------- 74
            +G+ GPPGPPGP G PG+ G+      DG  G PGLPGP G KG+ G+PG PG       
Sbjct: 898  MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 957

Query: 75   ----------EAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124
                      E GLPG+PGV G  G  G PG  G PG  G  G PGPPG   KG PG PG
Sbjct: 958  NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG--PKGNPGLPG 1015

Query: 125  EAGVSGPPG------------GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDL 172
            + G+ GPPG              G+ GPPGPSG+PG PG PG PG  G  G    G + +
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG--DPGISSI 1073

Query: 173  QCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGP---PGPAGLPGSVGLQG 229
              P +  PGP G PG+PG+ G  G KG  G+ G  G  G PG    PG  G PG+ G  G
Sbjct: 1074 GLPGL--PGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 230  PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGK------------AGDRGERGPEGFRG 277
            P+G+ G PG  G PG+ GP+G  G PG PG PG+            AG +GE G  GF  
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 278  P-----------KGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPG--------LDGQK 318
            P           KGD G PG  G PG+ GP GEPG  G  G  G PG        L+G K
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 319  GEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGER 378
            G  G  G PG  GP G  GLPG  G  G  G  G  GE G  G  G PG+PG  G  G  
Sbjct: 1252 GNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1311

Query: 379  GEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPK 438
            G  G+ G  G  G +G PG PGV GF G KG  G PG  GP+G  G +G  GP G  GP 
Sbjct: 1312 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1371

Query: 439  GDQ----------GIAGSDGLPGDKGELGPSGLVGPKGE------------SGSRGELGP 476
            G            GI G  GL G  G  GP GL GP G              G+ G  G 
Sbjct: 1372 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1431

Query: 477  KGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPG 508
             G  G  GT G+    GPPGP GLQG PG PG
Sbjct: 1432 PGLPGQPGTRGLD---GPPGPDGLQGPPGPPG 1460



 Score =  414 bits (1063), Expect = e-115
 Identities = 239/513 (46%), Positives = 273/513 (53%), Gaps = 59/513 (11%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGV---- 84
            G+PG  GP G  G PG  G  G +G PGLPGPPGPKG PG PG+PG  G PGL G     
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032

Query: 85   --DGLTGRDGPPGPKGAPGERGSLGPPGPPG---------LGGKGLPGPPGEAGVSGPPG 133
               G  G +GPPGP G PG+ GS G PG  G         +G  GLPGP GE G+ G PG
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 134  GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKG 193
              G++G  G  GLPGLPG PG  G PG PG           P    PGPPGP G+ G  G
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF----------PGT--PGPPGPKGISGPPG 1140

Query: 194  PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLG-----PPGDRGP 248
              G  GE G VG  G  G PGPPG  G PG  G+ GP G +G PG  G     PPG  G 
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 249  IGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVA--------GPSGEP 300
             G +G  G+PG PG  G  G +G  GF G  G  G PGP G+PG A        GP G P
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1260

Query: 301  GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGE---RGRAGEL 357
            G PG  G  G+PG +G  G  G  G  GEKG  G PGLPG  G KG++G    +G  G  
Sbjct: 1261 GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1320

Query: 358  GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQG---PPGAPGVRGFQGQ----KGS 410
            G  G  G+PG+PG  G PG +G +G  GSAG  G  G   PPG PG+ G  GQ    KG 
Sbjct: 1321 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1380

Query: 411  MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGS 470
             G PG+PG  GL+G  G +GP G  GP G  G  G +GLPG        G  G KG+ G 
Sbjct: 1381 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF------DGAGGRKGDPGL 1434

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGV 503
             G+ G +G  GP G  G+Q   GPPGP G   V
Sbjct: 1435 PGQPGTRGLDGPPGPDGLQ---GPPGPPGTSSV 1464



 Score =  336 bits (861), Expect = 5e-92
 Identities = 223/545 (40%), Positives = 257/545 (47%), Gaps = 86/545 (15%)

Query: 180 PGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGP 239
           PG  G PG+PGF GP G  G +G+ G DG    PGPPGP G+      +GP GL G PG 
Sbjct: 53  PGLEGHPGLPGFPGPEGPPGPRGQKGDDGI---PGPPGPKGI------RGPPGLPGFPGT 103

Query: 240 LGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGF---RGPKGDLGRPGPKGTPG---- 292
            G PG  G  G  GP GIPG  G  G+RG  G  GF   +GP G  G PG KG PG    
Sbjct: 104 PGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIM 163

Query: 293 --VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE--K 348
             + GP G PG PG  G  G+PG  G  G  G  G PG  GP G PGLPG  G+ G   +
Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223

Query: 349 GERGRAGELGEAGPSGEPGVPGDAGMP-------GERGEAGHRGSAGALGPQGPPGAPGV 401
           G +G  GE G  GP G PG   +   P       G++G  G RG  G  G +GPPG PG 
Sbjct: 224 GPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG- 282

Query: 402 RGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG- 460
            G +G+KG  G+PG  G  G  G+ G  G  G  G  G  G  G DG  G KG+ GP G 
Sbjct: 283 -GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP 341

Query: 461 --LVGPK-------GESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLG--LQGVPGVPGI 509
             LV P+       GE G+ G  G  G +G  G  G+QG PG PGP G  + G PG PG 
Sbjct: 342 PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGF 401

Query: 510 TGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPG 569
            G+ G  G E                              P  I  PGP G  G PG PG
Sbjct: 402 PGERGQKGDEG-----------------------------PPGISIPGPPGLDGQPGAPG 432

Query: 570 SIGHPGARGP----------PGYRGPTGELGDPGPRGNQGDRGDKG-----AAGAGLDGP 614
             G PG  GP          PG  GP G  GD G +G QG +GDKG       G G+ GP
Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 615 EGDQGPQGPQGVPGT-SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLG 673
            G  G  G  G PG+    GQ G  G+ G  G  GLPG  GA G PG   +    G +L 
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 674 GVGEK 678
             G K
Sbjct: 553 FPGMK 557



 Score =  335 bits (860), Expect = 6e-92
 Identities = 201/430 (46%), Positives = 229/430 (53%), Gaps = 45/430 (10%)

Query: 24   GAQRVGLPGPPGP---PGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPG 80
            G   +GLPG PGP   PG PG PG  GI G  G PGLPG PG  GA G+PG PG  G PG
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 81   LPGVDGLTGRDGPPGPKGAPGE---RGSLGPPGPPGLGGK----GLPGPPGEAGV----- 128
             PG  G++G  G PG  G PG     G  G PGPPG  GK    G+PGP G+ G      
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 129  ---SGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGP 185
                GPPG  GL G  G  GLPG+PG PG PGP G PG    G   +Q     PPGPPG 
Sbjct: 1189 FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF--HGFPGVQ----GPPGPPGS 1242

Query: 186  PGMPGFKGPTGYKGEQGEVGKDGE---KGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGP 242
            PG P  +GP G  G QG  G+ G    +G PGP GP GLPG+ G++G +G  G PG  G 
Sbjct: 1243 PG-PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1301

Query: 243  PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGM 302
            PG +G    +GPPG+ G PG+ G  G +G  G  G  G  G  GP G PG AGP GEPG+
Sbjct: 1302 PGLKGD---QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358

Query: 303  PGKDGQNGVPGLDGQ----KGEAGRNGAPGEKGPNGLP------GLPGRAGSKGEKGERG 352
             G  G  G+PG  GQ    KG+AG  G PG+ G  GLP      GLPG  G  G+ G  G
Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1418

Query: 353  RAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV-RGFQGQKGSM 411
              G  G  G  G+PG+P   G PG RG  G  G  G  GP GPPG   V  GF   + S 
Sbjct: 1419 LPGFDGAGGRKGDPGLP---GQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQ 1475

Query: 412  GDPGLPGPQG 421
                   PQG
Sbjct: 1476 TTDAPQCPQG 1485



 Score =  289 bits (740), Expect = 5e-78
 Identities = 160/341 (46%), Positives = 188/341 (55%), Gaps = 27/341 (7%)

Query: 15   LLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP--GPPGPKGAPGKPGK 72
            L GE     G    G PGPPG  G PG+ G  G  G+ G PG P  G PGP G PG  G+
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203

Query: 73   PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPP 132
             G+ GLPG+PG  GL G  G PG  G PG +   GPPGPPG  G  L GP G  G  GPP
Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ---GPPGPPGSPGPALEGPKGNPGPQGPP 1260

Query: 133  GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192
                  G PGP+G  GLPGP GPPG PG+ G+  E            PG PG PG+PG K
Sbjct: 1261 ------GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGN---------PGQPGLPGLPGLK 1305

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252
            G  G  G QG  G+ G  G  G PG  G+PG  G++GP    G+PG  GP G+ G IG  
Sbjct: 1306 GDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP---SGVPGSAGPEGEPGLIGPP 1362

Query: 253  GPPGIPGAPGKA-GDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
            GPPG+PG  G++   +G+ GP G  G  G  G PGP+G  G+ GP+G PG PG+   NG+
Sbjct: 1363 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR---NGL 1419

Query: 312  PGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG 352
            PG DG  G  G  G PG+ G  GL G PG  G +G  G  G
Sbjct: 1420 PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  534 bits (1376), Expect = e-152
 Identities = 318/700 (45%), Positives = 374/700 (53%), Gaps = 68/700 (9%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA---PGKPGKPGEAGLPGLPGVD 85
            G  GP G PGP G+ G+ G  G  G PG PG  GPKG+   PG PG  GE G  G+ G  
Sbjct: 829  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKP 888

Query: 86   GLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGL---RGPP 141
            G  G+ GP GP+G+ G RG  G PGP G  GG G PGPPGE G  GP G +G    +GPP
Sbjct: 889  GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 948

Query: 142  GPSGLPGLPGPPGP---------PGPPGHPGVL-PEGATDLQCP-----SICPPGPPGPP 186
            GP G  GLPG PG           GPPG  GV+ P+G T    P        PPGPPG  
Sbjct: 949  GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 1008

Query: 187  GMPGFKGPTGYKGE---QGEVGKDGEKGDPGPPGPAGLPGSVG---LQGPRGLRGLPGPL 240
            G+PG  G  G KG+   QG  GKDG  G  G PG  GLPG+ G   L+G  G +G PGP+
Sbjct: 1009 GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1068

Query: 241  GPPGDRGPIGFRGPPGIPGAPGKAGD---RGERGPEGFRGPKGDLGRPG---PKGTPGVA 294
            G PG+RG  G  GP G+PG PG  G     GE+G  G +GP+G  GR G   P G PG A
Sbjct: 1069 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1128

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGE---KGPNGLPGLPGRAGSKGEKGER 351
            GP+G PG  G  G+ G PG  G KG+ G NG PG    +GP G PG+ G  G  G +G++
Sbjct: 1129 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1188

Query: 352  GRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSM 411
            G  G+ G+ G  G PG PG  G+ G  G  G +G  G +GP GPPG PG RG QG  G+ 
Sbjct: 1189 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD 1248

Query: 412  GDPGLPGPQGLRGDVGDRGPGGAAG---PKGDQGIAGSDGLPGDKGELGPSGLVGPKGES 468
            G  G PG  G  G VG++G  G AG   P G+ G+ G  G  G+KGE GP G  GP G  
Sbjct: 1249 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1308

Query: 469  GSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGV---------------PGVPGITGKP 513
            G  G+ GPKG  GP G  G  G PG PGP G  GV               PG  G  G P
Sbjct: 1309 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1368

Query: 514  GVPGKE----ASEQRIRELCGGMISEQIAQLAAHLRKPLAP-GSIGRPGPAGPPGPPGPP 568
            G PGK     A+    R+   G   E  A+       P+ P G  G+PGP G  G PGP 
Sbjct: 1369 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1428

Query: 569  GSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVP 627
            G  G PGA G  G  GP G  G PG +G+ G +G+KG  G  GL GP G+QG +G +G+P
Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488

Query: 628  GTSKD----GQDGAPGEPGP---PGDPGLPGAIGAQGTPG 660
            GT       G  G PG  GP   PG PGLPG  G +G  G
Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1528



 Score =  525 bits (1351), Expect = e-149
 Identities = 320/774 (41%), Positives = 372/774 (48%), Gaps = 147/774 (18%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            G  GP GPPGPPG  G  G DGE GP GLPG  GP+G  G  G PG  G PG+ GVDG  
Sbjct: 628  GERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 687

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGG-KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147
            G  G  GP+G PG  G  G PGP GL G +G  GPPGE G  G PG  GL G  GP G P
Sbjct: 688  GPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP 747

Query: 148  GLPG---------PPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYK 198
            G  G         PPGP GP G+PG       D         G  G  G PGFKG  G K
Sbjct: 748  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 807

Query: 199  GEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP------RGLRGLPGPLGPPGDRGPIGFR 252
            G++GEVG+ G +G+ GP GP G  G  G  GP      +G  G+PG  G PG +GP G  
Sbjct: 808  GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST 867

Query: 253  GPPGIPGA------------PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300
            G PG PGA            PG  G RG  GP G RG +G  G+PGPKGT G  GP G P
Sbjct: 868  GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP 927

Query: 301  GM------------------PGKDGQNGVPGLDGQKGEAG-------------------- 322
            G                   PG  G++G+PG  GQ+GE G                    
Sbjct: 928  GERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 987

Query: 323  -------RNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMP 375
                     G PG  GP G  GLPG AG +G KG+ G  G  G+ GP+G  G PG+ G+P
Sbjct: 988  GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 1047

Query: 376  GERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAA 435
            G +G  G +G  G  GP GP G+PG RG  G  G +G PG PGPQG  G  G++G   A 
Sbjct: 1048 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG---AP 1104

Query: 436  GPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPP 495
            G KG QG AG DG+ G  G  GP+G  G  GE G +GE+G  G +G  G  G  G PGPP
Sbjct: 1105 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1164

Query: 496  GPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP----- 550
            G   LQG  G PGI G  G PG    +        GM  ++  + A     P  P     
Sbjct: 1165 G---LQGPVGAPGIAGGDGEPGPRGQQ--------GMFGQKGDEGARGFPGPPGPIGLQG 1213

Query: 551  -----------GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGY---------RGPTGELG 590
                       G +G  GP GPPGP GP G  G  G +GPPG          +G  GE G
Sbjct: 1214 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1273

Query: 591  DPGPRGN------QGDRGDKGAAGA-------GLDGPEGDQGPQG------------PQG 625
            +PGP G       +G+RG+KG AG        G  GP GD GP+G            P G
Sbjct: 1274 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG 1333

Query: 626  VPGTS----------KDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG 669
             PG +          +DG  G PG PGP G+ G PG  G +G PG       QG
Sbjct: 1334 EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1387



 Score =  519 bits (1337), Expect = e-147
 Identities = 307/682 (45%), Positives = 349/682 (51%), Gaps = 88/682 (12%)

Query: 27   RVGLPGPPGP------PGPPGKPGQDGIDGEAGPPG------LPGPPGPKGAPGKPGKPG 74
            R+ L GPPGP      PGP G PG  G  GE+G PG      + GPPGP G PGK G+PG
Sbjct: 536  RIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 595

Query: 75   E---AGLPGLPGVDGLTGRDGPPG---PKGAPGERGSLGPPGPPG----LGGKGLPGPPG 124
                 G+PG PG  G  G DG PG    KG  GERG  GPPGPPG     G  G  GP G
Sbjct: 596  ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 655

Query: 125  EAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPG 184
              G +GP G +G RG PG  G PG+ G  GPPGP G+ G               P G PG
Sbjct: 656  LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMG---------------PQGEPG 700

Query: 185  PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS---VGLQGPRGLRGLPGPLG 241
            PPG  G  GP G  G QG +G  GEKG  G PG AGLPG+    G  G  G  G  G LG
Sbjct: 701  PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 760

Query: 242  PPGDRGPIGFRGPPGIPGAP---GKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSG 298
            PPG +GPIG+ GP G+ GA    G  G +GE+G +GF G KGD+G  G +G  G  GP G
Sbjct: 761  PPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRG 820

Query: 299  EPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG 358
            E      DG  G  G  G  G+ G +G  GEKG  G+PGLPG  G +G KG  G  G  G
Sbjct: 821  E------DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 874

Query: 359  EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPG 418
              G  G  GV G  G  G+RG  G RGS GA GP G P         G KG+ G  G PG
Sbjct: 875  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP---------GPKGTSGGDGPPG 925

Query: 419  PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG 478
            P G RG  G +GP G  GPKG  G  G DGLPG  G+ G +G  G  G  G  G +GP+G
Sbjct: 926  PPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQG 985

Query: 479  TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538
              G  G  G +G PGPPGP G QG+PG  G  G  G PG +    +          +  A
Sbjct: 986  PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK----------DGPA 1035

Query: 539  QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQ 598
             L     +   PG+ G PG  G  GP GPPG +G PG RG  G  GP G  G PGP+G  
Sbjct: 1036 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1095

Query: 599  GDRGDKGAAGA----------GLDGPEGDQGPQGPQGVPGTSKD----------GQDGAP 638
            G  G+KGA G           G+ GP G  GP GP G PG   D          G  G  
Sbjct: 1096 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1155

Query: 639  GEPGPPGDPGLPGAIGAQGTPG 660
            GE GPPG PGL G +GA G  G
Sbjct: 1156 GENGPPGPPGLQGPVGAPGIAG 1177



 Score =  513 bits (1321), Expect = e-145
 Identities = 319/784 (40%), Positives = 376/784 (47%), Gaps = 168/784 (21%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPG---------------------------PP 61
            G+ GPPGP G PGK G+ G DG  G PG PG                           PP
Sbjct: 577  GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 636

Query: 62   GPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG----LGGK 117
            GP G  G  G+ GE G  GLPG  G  G  GP G  GAPG+ G  G  GPPG    +G +
Sbjct: 637  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 696

Query: 118  GLPGPPGEAGVSGP---PGGIGLRGPP---GPSGLPGLPGPPGPPGPPGHPGVLPEGATD 171
            G PGPPG+ G  GP   PG  G  GPP   GP G PGL G PG  GPPGHPG   EG + 
Sbjct: 697  GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG--KEGQSG 754

Query: 172  LQCPSICPPGPPGP---------------------------PGMPGFKGPTGYKGEQGEV 204
             +  ++ PPGP GP                            G PGFKG  G KG++GEV
Sbjct: 755  -EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 813

Query: 205  GKDGEKGDPGPPGPAGL------PGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIP 258
            G+ G +G+ GP GP G       PG  G  G +G  G+PG  G PG +GP G  G PG P
Sbjct: 814  GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 873

Query: 259  GA------------PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP------ 300
            GA            PG  G RG  GP G RG +G  G+PGPKGT G  GP G P      
Sbjct: 874  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 933

Query: 301  ------------GMPGKDGQNGVPGLDGQKGEA--------------------------- 321
                        G PG  G++G+PG  GQ+GE                            
Sbjct: 934  GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPI 993

Query: 322  GRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEA 381
            G  G PG  GP G  GLPG AG +G KG+ G  G  G+ GP+G  G PG+ G+PG +G  
Sbjct: 994  GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1053

Query: 382  GHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQ 441
            G +G  G  GP GP G+PG RG  G  G +G PG PGPQG  G  G++   GA G KG Q
Sbjct: 1054 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK---GAPGEKGPQ 1110

Query: 442  GIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQ 501
            G AG DG+ G  G  GP+G  G  GE G +GE+G  G +G  G  G  G PGPP   GLQ
Sbjct: 1111 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP---GLQ 1167

Query: 502  GVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP----------- 550
            G  G PGI G  G PG    +        GM  ++  + A     P  P           
Sbjct: 1168 GPVGAPGIAGGDGEPGPRGQQ--------GMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219

Query: 551  --GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG 608
              G  G  GP GPPGPPGP G  G  GA GP G  G  G +G  G +G  G+ G+ G  G
Sbjct: 1220 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1279

Query: 609  -AGLDGPEGDQGPQGPQGVPGTS-------KDGQDGAPGEPGP---PGDPGLPGAIGAQG 657
             AG+ GP+G++G +G  G PG +         G DG  G PGP   PGDPG PG  G  G
Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1339

Query: 658  TPGI 661
              G+
Sbjct: 1340 QDGV 1343



 Score =  501 bits (1291), Expect = e-142
 Identities = 299/722 (41%), Positives = 354/722 (49%), Gaps = 124/722 (17%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK------- 69
            GE  A   A + G  G  GP GP G  G  G  G+ GP G  G  GP G PG+       
Sbjct: 877  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 936

Query: 70   -----------PGKPGEAGLPGLPGVDGLT---GRDGPPGPKGAP------------GER 103
                       PG PG+ GLPG PG  G T   G+ GPPGP G              GER
Sbjct: 937  GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 996

Query: 104  GSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG 163
            G  GPPGPP  G +GLPG  G+ G  G PG  G+ G  GP+GL G PG  G PG  G PG
Sbjct: 997  GHPGPPGPP--GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG 1054

Query: 164  VL-PEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLP 222
            +   EG          P GPPGP G PG +G  G  G  G  G+ G +G PGP G  G P
Sbjct: 1055 LKGGEG----------PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1104

Query: 223  GSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDL 282
            G  G QGP G  G+ GP+G PG  GP          G+PG+ GD+GE G  G +G KGD 
Sbjct: 1105 GEKGPQGPAGRDGVQGPVGLPGPAGP---------AGSPGEDGDKGEIGEPGQKGSKGDK 1155

Query: 283  GRPGPKGTPGVAGPSGEPGMPGKDGQ---NGVPGLDGQKGEAGRNGAPGEKGPNGLPGLP 339
            G  GP G PG+ GP G PG+ G DG+    G  G+ GQKG+ G  G PG  GP GL GLP
Sbjct: 1156 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLP 1215

Query: 340  GRAGSKGEKGE---------------------------------RGRAGELGEAGPSGEP 366
            G  G KGE G+                                  G  GE GE G +G P
Sbjct: 1216 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1275

Query: 367  GVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDV 426
            G PG+AG+ G +GE G +G AG  G  GPPGA G  G  G KG+ G  G PG  G  G+ 
Sbjct: 1276 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1335

Query: 427  GDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTS 486
            G  G  G  G KG+ G  G  G PG  GE GP G  G +G  G+ G  G +G +G  G +
Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1395

Query: 487  GVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRK 546
            G +G PG  GP+G QG  G PG  G  G+PG    EQ +                     
Sbjct: 1396 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG-PVGEQGL--------------------- 1433

Query: 547  PLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGA 606
               PG+ G+ GP GP GPPG PG  G PG++G  G+ G  G +G PG +G +GDRG  G 
Sbjct: 1434 ---PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1490

Query: 607  AGA-------GLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGPPGDPGLPGAIGAQGT 658
             G+       G+ GP G  GP GP G+PG     G  G+ G  G  GD GLPG  G+ G 
Sbjct: 1491 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1550

Query: 659  PG 660
            PG
Sbjct: 1551 PG 1552



 Score =  472 bits (1214), Expect = e-133
 Identities = 288/640 (45%), Positives = 317/640 (49%), Gaps = 92/640 (14%)

Query: 28   VGLPGPPGPPGPPGK---------------------PGQDGIDGEAGPPGLPGPPGPKGA 66
            VG PGP GPPGPPGK                     PG  G+ G  GP G  GP G +G 
Sbjct: 939  VGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH 998

Query: 67   PGKPGKPGEAGLPGL---------PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GG 116
            PG PG PGE GLPG          PG  G++G+DGP G +G PGERG  G  G PGL GG
Sbjct: 999  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058

Query: 117  KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-------PEGA 169
            +G  GPPG  G    PG  G  G  GP GLPG PGP GPPGP G  G         P G 
Sbjct: 1059 EGPQGPPGPVG---SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1115

Query: 170  TDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQG 229
              +Q P +  PGP GP G PG  G  G  GE G+ G  G+KG+ GPPGP GL G VG  G
Sbjct: 1116 DGVQGP-VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1174

Query: 230  PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKG 289
              G  G PGP G  G  G  G  G  G PG PG  G +G  GP G +G  GD+G  GP G
Sbjct: 1175 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1234

Query: 290  TPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKG 349
             PG  GP G  G    DG  G PG  G  G  G  G PGE G  G PG  G  G KGE+G
Sbjct: 1235 PPGPRGPQGPNGA---DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1291

Query: 350  ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKG 409
            E+G AG  G AGP G  G PGD G  G  G  G  G  G  G  GP G  GV G +G+ G
Sbjct: 1292 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1351

Query: 410  SMGDPGLPGPQGLRGDVGD---RGPGGAAGPKGDQGI------AGSDGLPGDKGELGPSG 460
              G PG PGP G  G  G    RGP GAAG +G QG       AG++G PG  G +GP G
Sbjct: 1352 DPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1411

Query: 461  LVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK-- 518
              G  G  G RG  GP G QG  G +G  G PGP GP GL G+ G PG  G+ G PG   
Sbjct: 1412 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIG 1471

Query: 519  ------EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG 572
                  E  E+  R L G   S            P A G  G PGPAGP GPPGPPG  G
Sbjct: 1472 LIGPPGEQGEKGDRGLPGTQGS------------PGAKGDGGIPGPAGPLGPPGPPGLPG 1519

Query: 573  HPGARG------------------PPGYRGPTGELGDPGP 594
              G +G                  PPG  GP GE+  P P
Sbjct: 1520 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559



 Score =  444 bits (1142), Expect = e-124
 Identities = 290/684 (42%), Positives = 335/684 (48%), Gaps = 64/684 (9%)

Query: 48   IDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT-------GRDGPPGPKGAP 100
            +DG+ G          +  P  P  P E   PG+P    +T       G  G  G KG P
Sbjct: 386  VDGDLGEYDFYEYKEYEDKPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEP 443

Query: 101  G--ERGSL--GPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPP 156
               E G L  GPPGP G  G  + GPPG  G +GPPG  G RGPPG  GLPG  G PGPP
Sbjct: 444  AVVEPGMLVEGPPGPAGPAG--IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 501

Query: 157  G-----PPGHPGVLPEGATD----------LQCPSICPPGPPGPPGMPGFKGPTGYKGEQ 201
            G     P  + G   +G T           LQ   I   GPPGP G+ G  GP G  G  
Sbjct: 502  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 561

Query: 202  GEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAP 261
            G  G+ G+ G  GP G  G PG  G  G RG  G  G  G PG+ G  G RG  G+PG P
Sbjct: 562  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 621

Query: 262  GKAGDRGERGPEGFRGPKGD------LGRPGPKGTPGVA------GPSGEPGMPGKDGQN 309
            G  G RGERGP+G  GP GD       G  GP+G PG A      GP G PG PG+ G  
Sbjct: 622  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681

Query: 310  GVPGLDGQKGEAGRNGAP------GEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPS 363
            GV G  G KG  G  G P      G  GP GLPG  G  G  GEKG +G+ G  G  G  
Sbjct: 682  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741

Query: 364  GEPGVPGDAGMPGERGEAGHRGSAGAL---GPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420
            G PG PG  G  GE+G  G  G  G +   GP+G  GA GVRG +G KG  G+ G PG +
Sbjct: 742  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801

Query: 421  GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480
            G  G  GDRG  G  GP+G+ G  G  G  G  G+ GPSG  G KG+ G  G  G  G Q
Sbjct: 802  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 861

Query: 481  GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG-----GMISE 535
            GP G++G  G PG  G  G +GV G PG  G+ G  G   S +  R   G     G    
Sbjct: 862  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGS-RGARGPTGKPGPKGTSGG 920

Query: 536  QIAQLAAHLRKPLAP-GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGP 594
                     R P  P G +G PGP GPPGPPG  G  GHPG RG  G++G TG  G  G 
Sbjct: 921  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 980

Query: 595  RGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIG 654
             G QG  G+ G  G    G  G  GP G QG+PG +  G++GA G+PGP G  G  G  G
Sbjct: 981  VGPQGPTGETGPIGE--RGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAG 1036

Query: 655  AQGTPGICDTSACQGA--VLGGVG 676
             +G PG       QGA  + GG G
Sbjct: 1037 LRGFPGERGLPGAQGAPGLKGGEG 1060



 Score =  426 bits (1095), Expect = e-119
 Identities = 246/543 (45%), Positives = 291/543 (53%), Gaps = 53/543 (9%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            GE  +A  A  +GLPG PGP GPPG  G+ G  GE GP G   P G  G  G  G PG A
Sbjct: 1072 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG---PAGRDGVQGPVGLPGPA 1128

Query: 77   GLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL----------GGKGLPGPPGEA 126
            G  G PG DG  G  G PG KG+ G++G  GPPGPPGL          GG G PGP G+ 
Sbjct: 1129 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1188

Query: 127  GVSGPPGGIGLRG---PPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGP 182
            G+ G  G  G RG   PPGP GL GLPGPPG  G  G  G + P G          PPGP
Sbjct: 1189 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG----------PPGP 1238

Query: 183  PGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGP 242
             GP G  G  GP G  G  G VG  GEKG+PG  G  G PG  G+ GP+G RG  G  GP
Sbjct: 1239 RGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGP 1298

Query: 243  PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGM 302
            PG  GP G +GPPG            + GP+G  GP G  G PGP G PG AG  G  G 
Sbjct: 1299 PGAAGPPGAKGPPG------------DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1346

Query: 303  PGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG------RAGE 356
             G+DG  G PG  G  GEAG  G PG++GP G  G  GR G KG KGE G      + G 
Sbjct: 1347 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1406

Query: 357  LGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA---LGPQGPPGAPGVRGFQGQKGSMGD 413
            +G  GP+G+PG  G  G+PG  GE G  G+AG     GP GPPG PG++G  G KG  G 
Sbjct: 1407 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1466

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL---GPSGLVGPKGESGS 470
            PGL G  G  G+ G++G  G  G +G  G  G  G+PG  G L   GP GL GP+G  G+
Sbjct: 1467 PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1526

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-SEQRIRELC 529
            +G  GP G +G +G  G  G PGPPG + +Q +P +     +    G +A ++  I +  
Sbjct: 1527 KGSTGPAGQKGDSGLPGPPGSPGPPGEV-IQPLPILSSKKTRRHTEGMQADADDNILDYS 1585

Query: 530  GGM 532
             GM
Sbjct: 1586 DGM 1588



 Score =  124 bits (312), Expect = 2e-28
 Identities = 72/145 (49%), Positives = 77/145 (53%), Gaps = 20/145 (13%)

Query: 16   LGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE 75
            +GE      A + G PGP GPPG PG  G  G  GE G PGL G  GP   PG+ G+ G+
Sbjct: 1428 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP---PGEQGEKGD 1484

Query: 76   AGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
             GLPG  G  G  G  G PGP       G LGPPGPP     GLPGP       GP G  
Sbjct: 1485 RGLPGTQGSPGAKGDGGIPGP------AGPLGPPGPP-----GLPGP------QGPKGNK 1527

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPG 160
            G  GP G  G  GLPGPPG PGPPG
Sbjct: 1528 GSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 42/123 (34%), Positives = 51/123 (41%), Gaps = 6/123 (4%)

Query: 564 PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGL--DGPEGDQGPQ 621
           P  PP     PG   P         +   G  G +G +G+      G+  +GP G  GP 
Sbjct: 405 PTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 462

Query: 622 GPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGS 681
           G  G PG    G  G PG+PG  G PG PG  GA G PG   T        GG G K  +
Sbjct: 463 GIMGPPGLQ--GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT 520

Query: 682 RSS 684
            S+
Sbjct: 521 ISA 523


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  534 bits (1376), Expect = e-152
 Identities = 318/700 (45%), Positives = 374/700 (53%), Gaps = 68/700 (9%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA---PGKPGKPGEAGLPGLPGVD 85
            G  GP G PGP G+ G+ G  G  G PG PG  GPKG+   PG PG  GE G  G+ G  
Sbjct: 778  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKP 837

Query: 86   GLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGL---RGPP 141
            G  G+ GP GP+G+ G RG  G PGP G  GG G PGPPGE G  GP G +G    +GPP
Sbjct: 838  GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 897

Query: 142  GPSGLPGLPGPPGP---------PGPPGHPGVL-PEGATDLQCP-----SICPPGPPGPP 186
            GP G  GLPG PG           GPPG  GV+ P+G T    P        PPGPPG  
Sbjct: 898  GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 957

Query: 187  GMPGFKGPTGYKGE---QGEVGKDGEKGDPGPPGPAGLPGSVG---LQGPRGLRGLPGPL 240
            G+PG  G  G KG+   QG  GKDG  G  G PG  GLPG+ G   L+G  G +G PGP+
Sbjct: 958  GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1017

Query: 241  GPPGDRGPIGFRGPPGIPGAPGKAGD---RGERGPEGFRGPKGDLGRPG---PKGTPGVA 294
            G PG+RG  G  GP G+PG PG  G     GE+G  G +GP+G  GR G   P G PG A
Sbjct: 1018 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1077

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGE---KGPNGLPGLPGRAGSKGEKGER 351
            GP+G PG  G  G+ G PG  G KG+ G NG PG    +GP G PG+ G  G  G +G++
Sbjct: 1078 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1137

Query: 352  GRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSM 411
            G  G+ G+ G  G PG PG  G+ G  G  G +G  G +GP GPPG PG RG QG  G+ 
Sbjct: 1138 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD 1197

Query: 412  GDPGLPGPQGLRGDVGDRGPGGAAG---PKGDQGIAGSDGLPGDKGELGPSGLVGPKGES 468
            G  G PG  G  G VG++G  G AG   P G+ G+ G  G  G+KGE GP G  GP G  
Sbjct: 1198 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257

Query: 469  GSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGV---------------PGVPGITGKP 513
            G  G+ GPKG  GP G  G  G PG PGP G  GV               PG  G  G P
Sbjct: 1258 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1317

Query: 514  GVPGKE----ASEQRIRELCGGMISEQIAQLAAHLRKPLAP-GSIGRPGPAGPPGPPGPP 568
            G PGK     A+    R+   G   E  A+       P+ P G  G+PGP G  G PGP 
Sbjct: 1318 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1377

Query: 569  GSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVP 627
            G  G PGA G  G  GP G  G PG +G+ G +G+KG  G  GL GP G+QG +G +G+P
Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437

Query: 628  GTSKD----GQDGAPGEPGP---PGDPGLPGAIGAQGTPG 660
            GT       G  G PG  GP   PG PGLPG  G +G  G
Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1477



 Score =  525 bits (1351), Expect = e-149
 Identities = 320/774 (41%), Positives = 372/774 (48%), Gaps = 147/774 (18%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            G  GP GPPGPPG  G  G DGE GP GLPG  GP+G  G  G PG  G PG+ GVDG  
Sbjct: 577  GERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 636

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGG-KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147
            G  G  GP+G PG  G  G PGP GL G +G  GPPGE G  G PG  GL G  GP G P
Sbjct: 637  GPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP 696

Query: 148  GLPG---------PPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYK 198
            G  G         PPGP GP G+PG       D         G  G  G PGFKG  G K
Sbjct: 697  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 756

Query: 199  GEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP------RGLRGLPGPLGPPGDRGPIGFR 252
            G++GEVG+ G +G+ GP GP G  G  G  GP      +G  G+PG  G PG +GP G  
Sbjct: 757  GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST 816

Query: 253  GPPGIPGA------------PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300
            G PG PGA            PG  G RG  GP G RG +G  G+PGPKGT G  GP G P
Sbjct: 817  GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP 876

Query: 301  GM------------------PGKDGQNGVPGLDGQKGEAG-------------------- 322
            G                   PG  G++G+PG  GQ+GE G                    
Sbjct: 877  GERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 936

Query: 323  -------RNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMP 375
                     G PG  GP G  GLPG AG +G KG+ G  G  G+ GP+G  G PG+ G+P
Sbjct: 937  GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 996

Query: 376  GERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAA 435
            G +G  G +G  G  GP GP G+PG RG  G  G +G PG PGPQG  G  G++G   A 
Sbjct: 997  GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG---AP 1053

Query: 436  GPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPP 495
            G KG QG AG DG+ G  G  GP+G  G  GE G +GE+G  G +G  G  G  G PGPP
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113

Query: 496  GPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP----- 550
            G   LQG  G PGI G  G PG    +        GM  ++  + A     P  P     
Sbjct: 1114 G---LQGPVGAPGIAGGDGEPGPRGQQ--------GMFGQKGDEGARGFPGPPGPIGLQG 1162

Query: 551  -----------GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGY---------RGPTGELG 590
                       G +G  GP GPPGP GP G  G  G +GPPG          +G  GE G
Sbjct: 1163 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1222

Query: 591  DPGPRGN------QGDRGDKGAAGA-------GLDGPEGDQGPQG------------PQG 625
            +PGP G       +G+RG+KG AG        G  GP GD GP+G            P G
Sbjct: 1223 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG 1282

Query: 626  VPGTS----------KDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG 669
             PG +          +DG  G PG PGP G+ G PG  G +G PG       QG
Sbjct: 1283 EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1336



 Score =  519 bits (1337), Expect = e-147
 Identities = 307/682 (45%), Positives = 349/682 (51%), Gaps = 88/682 (12%)

Query: 27   RVGLPGPPGP------PGPPGKPGQDGIDGEAGPPG------LPGPPGPKGAPGKPGKPG 74
            R+ L GPPGP      PGP G PG  G  GE+G PG      + GPPGP G PGK G+PG
Sbjct: 485  RIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 544

Query: 75   E---AGLPGLPGVDGLTGRDGPPG---PKGAPGERGSLGPPGPPG----LGGKGLPGPPG 124
                 G+PG PG  G  G DG PG    KG  GERG  GPPGPPG     G  G  GP G
Sbjct: 545  ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 604

Query: 125  EAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPG 184
              G +GP G +G RG PG  G PG+ G  GPPGP G+ G               P G PG
Sbjct: 605  LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMG---------------PQGEPG 649

Query: 185  PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS---VGLQGPRGLRGLPGPLG 241
            PPG  G  GP G  G QG +G  GEKG  G PG AGLPG+    G  G  G  G  G LG
Sbjct: 650  PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 709

Query: 242  PPGDRGPIGFRGPPGIPGAP---GKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSG 298
            PPG +GPIG+ GP G+ GA    G  G +GE+G +GF G KGD+G  G +G  G  GP G
Sbjct: 710  PPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRG 769

Query: 299  EPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG 358
            E      DG  G  G  G  G+ G +G  GEKG  G+PGLPG  G +G KG  G  G  G
Sbjct: 770  E------DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823

Query: 359  EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPG 418
              G  G  GV G  G  G+RG  G RGS GA GP G P         G KG+ G  G PG
Sbjct: 824  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP---------GPKGTSGGDGPPG 874

Query: 419  PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG 478
            P G RG  G +GP G  GPKG  G  G DGLPG  G+ G +G  G  G  G  G +GP+G
Sbjct: 875  PPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQG 934

Query: 479  TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538
              G  G  G +G PGPPGP G QG+PG  G  G  G PG +    +          +  A
Sbjct: 935  PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK----------DGPA 984

Query: 539  QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQ 598
             L     +   PG+ G PG  G  GP GPPG +G PG RG  G  GP G  G PGP+G  
Sbjct: 985  GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1044

Query: 599  GDRGDKGAAGA----------GLDGPEGDQGPQGPQGVPGTSKD----------GQDGAP 638
            G  G+KGA G           G+ GP G  GP GP G PG   D          G  G  
Sbjct: 1045 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1104

Query: 639  GEPGPPGDPGLPGAIGAQGTPG 660
            GE GPPG PGL G +GA G  G
Sbjct: 1105 GENGPPGPPGLQGPVGAPGIAG 1126



 Score =  513 bits (1321), Expect = e-145
 Identities = 319/784 (40%), Positives = 376/784 (47%), Gaps = 168/784 (21%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPG---------------------------PP 61
            G+ GPPGP G PGK G+ G DG  G PG PG                           PP
Sbjct: 526  GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 585

Query: 62   GPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG----LGGK 117
            GP G  G  G+ GE G  GLPG  G  G  GP G  GAPG+ G  G  GPPG    +G +
Sbjct: 586  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 645

Query: 118  GLPGPPGEAGVSGP---PGGIGLRGPP---GPSGLPGLPGPPGPPGPPGHPGVLPEGATD 171
            G PGPPG+ G  GP   PG  G  GPP   GP G PGL G PG  GPPGHPG   EG + 
Sbjct: 646  GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG--KEGQSG 703

Query: 172  LQCPSICPPGPPGP---------------------------PGMPGFKGPTGYKGEQGEV 204
             +  ++ PPGP GP                            G PGFKG  G KG++GEV
Sbjct: 704  -EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 762

Query: 205  GKDGEKGDPGPPGPAGL------PGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIP 258
            G+ G +G+ GP GP G       PG  G  G +G  G+PG  G PG +GP G  G PG P
Sbjct: 763  GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 822

Query: 259  GA------------PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP------ 300
            GA            PG  G RG  GP G RG +G  G+PGPKGT G  GP G P      
Sbjct: 823  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 882

Query: 301  ------------GMPGKDGQNGVPGLDGQKGEA--------------------------- 321
                        G PG  G++G+PG  GQ+GE                            
Sbjct: 883  GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPI 942

Query: 322  GRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEA 381
            G  G PG  GP G  GLPG AG +G KG+ G  G  G+ GP+G  G PG+ G+PG +G  
Sbjct: 943  GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002

Query: 382  GHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQ 441
            G +G  G  GP GP G+PG RG  G  G +G PG PGPQG  G  G++   GA G KG Q
Sbjct: 1003 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK---GAPGEKGPQ 1059

Query: 442  GIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQ 501
            G AG DG+ G  G  GP+G  G  GE G +GE+G  G +G  G  G  G PGPP   GLQ
Sbjct: 1060 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP---GLQ 1116

Query: 502  GVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP----------- 550
            G  G PGI G  G PG    +        GM  ++  + A     P  P           
Sbjct: 1117 GPVGAPGIAGGDGEPGPRGQQ--------GMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168

Query: 551  --GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG 608
              G  G  GP GPPGPPGP G  G  GA GP G  G  G +G  G +G  G+ G+ G  G
Sbjct: 1169 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1228

Query: 609  -AGLDGPEGDQGPQGPQGVPGTS-------KDGQDGAPGEPGP---PGDPGLPGAIGAQG 657
             AG+ GP+G++G +G  G PG +         G DG  G PGP   PGDPG PG  G  G
Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1288

Query: 658  TPGI 661
              G+
Sbjct: 1289 QDGV 1292



 Score =  501 bits (1291), Expect = e-142
 Identities = 299/722 (41%), Positives = 354/722 (49%), Gaps = 124/722 (17%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK------- 69
            GE  A   A + G  G  GP GP G  G  G  G+ GP G  G  GP G PG+       
Sbjct: 826  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 885

Query: 70   -----------PGKPGEAGLPGLPGVDGLT---GRDGPPGPKGAP------------GER 103
                       PG PG+ GLPG PG  G T   G+ GPPGP G              GER
Sbjct: 886  GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 945

Query: 104  GSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG 163
            G  GPPGPP  G +GLPG  G+ G  G PG  G+ G  GP+GL G PG  G PG  G PG
Sbjct: 946  GHPGPPGPP--GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG 1003

Query: 164  VL-PEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLP 222
            +   EG          P GPPGP G PG +G  G  G  G  G+ G +G PGP G  G P
Sbjct: 1004 LKGGEG----------PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053

Query: 223  GSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDL 282
            G  G QGP G  G+ GP+G PG  GP          G+PG+ GD+GE G  G +G KGD 
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGP---------AGSPGEDGDKGEIGEPGQKGSKGDK 1104

Query: 283  GRPGPKGTPGVAGPSGEPGMPGKDGQ---NGVPGLDGQKGEAGRNGAPGEKGPNGLPGLP 339
            G  GP G PG+ GP G PG+ G DG+    G  G+ GQKG+ G  G PG  GP GL GLP
Sbjct: 1105 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLP 1164

Query: 340  GRAGSKGEKGE---------------------------------RGRAGELGEAGPSGEP 366
            G  G KGE G+                                  G  GE GE G +G P
Sbjct: 1165 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1224

Query: 367  GVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDV 426
            G PG+AG+ G +GE G +G AG  G  GPPGA G  G  G KG+ G  G PG  G  G+ 
Sbjct: 1225 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1284

Query: 427  GDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTS 486
            G  G  G  G KG+ G  G  G PG  GE GP G  G +G  G+ G  G +G +G  G +
Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1344

Query: 487  GVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRK 546
            G +G PG  GP+G QG  G PG  G  G+PG    EQ +                     
Sbjct: 1345 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG-PVGEQGL--------------------- 1382

Query: 547  PLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGA 606
               PG+ G+ GP GP GPPG PG  G PG++G  G+ G  G +G PG +G +GDRG  G 
Sbjct: 1383 ---PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1439

Query: 607  AGA-------GLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGPPGDPGLPGAIGAQGT 658
             G+       G+ GP G  GP GP G+PG     G  G+ G  G  GD GLPG  G+ G 
Sbjct: 1440 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1499

Query: 659  PG 660
            PG
Sbjct: 1500 PG 1501



 Score =  472 bits (1214), Expect = e-133
 Identities = 288/640 (45%), Positives = 317/640 (49%), Gaps = 92/640 (14%)

Query: 28   VGLPGPPGPPGPPGK---------------------PGQDGIDGEAGPPGLPGPPGPKGA 66
            VG PGP GPPGPPGK                     PG  G+ G  GP G  GP G +G 
Sbjct: 888  VGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH 947

Query: 67   PGKPGKPGEAGLPGL---------PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GG 116
            PG PG PGE GLPG          PG  G++G+DGP G +G PGERG  G  G PGL GG
Sbjct: 948  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007

Query: 117  KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-------PEGA 169
            +G  GPPG  G    PG  G  G  GP GLPG PGP GPPGP G  G         P G 
Sbjct: 1008 EGPQGPPGPVG---SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1064

Query: 170  TDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQG 229
              +Q P +  PGP GP G PG  G  G  GE G+ G  G+KG+ GPPGP GL G VG  G
Sbjct: 1065 DGVQGP-VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1123

Query: 230  PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKG 289
              G  G PGP G  G  G  G  G  G PG PG  G +G  GP G +G  GD+G  GP G
Sbjct: 1124 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1183

Query: 290  TPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKG 349
             PG  GP G  G    DG  G PG  G  G  G  G PGE G  G PG  G  G KGE+G
Sbjct: 1184 PPGPRGPQGPNGA---DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1240

Query: 350  ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKG 409
            E+G AG  G AGP G  G PGD G  G  G  G  G  G  G  GP G  GV G +G+ G
Sbjct: 1241 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1300

Query: 410  SMGDPGLPGPQGLRGDVGD---RGPGGAAGPKGDQGI------AGSDGLPGDKGELGPSG 460
              G PG PGP G  G  G    RGP GAAG +G QG       AG++G PG  G +GP G
Sbjct: 1301 DPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1360

Query: 461  LVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK-- 518
              G  G  G RG  GP G QG  G +G  G PGP GP GL G+ G PG  G+ G PG   
Sbjct: 1361 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIG 1420

Query: 519  ------EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG 572
                  E  E+  R L G   S            P A G  G PGPAGP GPPGPPG  G
Sbjct: 1421 LIGPPGEQGEKGDRGLPGTQGS------------PGAKGDGGIPGPAGPLGPPGPPGLPG 1468

Query: 573  HPGARG------------------PPGYRGPTGELGDPGP 594
              G +G                  PPG  GP GE+  P P
Sbjct: 1469 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508



 Score =  444 bits (1142), Expect = e-124
 Identities = 290/684 (42%), Positives = 335/684 (48%), Gaps = 64/684 (9%)

Query: 48   IDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT-------GRDGPPGPKGAP 100
            +DG+ G          +  P  P  P E   PG+P    +T       G  G  G KG P
Sbjct: 335  VDGDLGEYDFYEYKEYEDKPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEP 392

Query: 101  G--ERGSL--GPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPP 156
               E G L  GPPGP G  G  + GPPG  G +GPPG  G RGPPG  GLPG  G PGPP
Sbjct: 393  AVVEPGMLVEGPPGPAGPAG--IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 450

Query: 157  G-----PPGHPGVLPEGATD----------LQCPSICPPGPPGPPGMPGFKGPTGYKGEQ 201
            G     P  + G   +G T           LQ   I   GPPGP G+ G  GP G  G  
Sbjct: 451  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 510

Query: 202  GEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAP 261
            G  G+ G+ G  GP G  G PG  G  G RG  G  G  G PG+ G  G RG  G+PG P
Sbjct: 511  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 570

Query: 262  GKAGDRGERGPEGFRGPKGD------LGRPGPKGTPGVA------GPSGEPGMPGKDGQN 309
            G  G RGERGP+G  GP GD       G  GP+G PG A      GP G PG PG+ G  
Sbjct: 571  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630

Query: 310  GVPGLDGQKGEAGRNGAP------GEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPS 363
            GV G  G KG  G  G P      G  GP GLPG  G  G  GEKG +G+ G  G  G  
Sbjct: 631  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690

Query: 364  GEPGVPGDAGMPGERGEAGHRGSAGAL---GPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420
            G PG PG  G  GE+G  G  G  G +   GP+G  GA GVRG +G KG  G+ G PG +
Sbjct: 691  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750

Query: 421  GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480
            G  G  GDRG  G  GP+G+ G  G  G  G  G+ GPSG  G KG+ G  G  G  G Q
Sbjct: 751  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 810

Query: 481  GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG-----GMISE 535
            GP G++G  G PG  G  G +GV G PG  G+ G  G   S +  R   G     G    
Sbjct: 811  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGS-RGARGPTGKPGPKGTSGG 869

Query: 536  QIAQLAAHLRKPLAP-GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGP 594
                     R P  P G +G PGP GPPGPPG  G  GHPG RG  G++G TG  G  G 
Sbjct: 870  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929

Query: 595  RGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIG 654
             G QG  G+ G  G    G  G  GP G QG+PG +  G++GA G+PGP G  G  G  G
Sbjct: 930  VGPQGPTGETGPIGE--RGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAG 985

Query: 655  AQGTPGICDTSACQGA--VLGGVG 676
             +G PG       QGA  + GG G
Sbjct: 986  LRGFPGERGLPGAQGAPGLKGGEG 1009



 Score =  426 bits (1095), Expect = e-119
 Identities = 246/543 (45%), Positives = 291/543 (53%), Gaps = 53/543 (9%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            GE  +A  A  +GLPG PGP GPPG  G+ G  GE GP G   P G  G  G  G PG A
Sbjct: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG---PAGRDGVQGPVGLPGPA 1077

Query: 77   GLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL----------GGKGLPGPPGEA 126
            G  G PG DG  G  G PG KG+ G++G  GPPGPPGL          GG G PGP G+ 
Sbjct: 1078 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1137

Query: 127  GVSGPPGGIGLRG---PPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGP 182
            G+ G  G  G RG   PPGP GL GLPGPPG  G  G  G + P G          PPGP
Sbjct: 1138 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG----------PPGP 1187

Query: 183  PGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGP 242
             GP G  G  GP G  G  G VG  GEKG+PG  G  G PG  G+ GP+G RG  G  GP
Sbjct: 1188 RGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGP 1247

Query: 243  PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGM 302
            PG  GP G +GPPG            + GP+G  GP G  G PGP G PG AG  G  G 
Sbjct: 1248 PGAAGPPGAKGPPG------------DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1295

Query: 303  PGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG------RAGE 356
             G+DG  G PG  G  GEAG  G PG++GP G  G  GR G KG KGE G      + G 
Sbjct: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355

Query: 357  LGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA---LGPQGPPGAPGVRGFQGQKGSMGD 413
            +G  GP+G+PG  G  G+PG  GE G  G+AG     GP GPPG PG++G  G KG  G 
Sbjct: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1415

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL---GPSGLVGPKGESGS 470
            PGL G  G  G+ G++G  G  G +G  G  G  G+PG  G L   GP GL GP+G  G+
Sbjct: 1416 PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1475

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-SEQRIRELC 529
            +G  GP G +G +G  G  G PGPPG + +Q +P +     +    G +A ++  I +  
Sbjct: 1476 KGSTGPAGQKGDSGLPGPPGSPGPPGEV-IQPLPILSSKKTRRHTEGMQADADDNILDYS 1534

Query: 530  GGM 532
             GM
Sbjct: 1535 DGM 1537



 Score =  124 bits (312), Expect = 2e-28
 Identities = 72/145 (49%), Positives = 77/145 (53%), Gaps = 20/145 (13%)

Query: 16   LGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE 75
            +GE      A + G PGP GPPG PG  G  G  GE G PGL G  GP   PG+ G+ G+
Sbjct: 1377 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP---PGEQGEKGD 1433

Query: 76   AGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
             GLPG  G  G  G  G PGP       G LGPPGPP     GLPGP       GP G  
Sbjct: 1434 RGLPGTQGSPGAKGDGGIPGP------AGPLGPPGPP-----GLPGP------QGPKGNK 1476

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPG 160
            G  GP G  G  GLPGPPG PGPPG
Sbjct: 1477 GSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 42/123 (34%), Positives = 51/123 (41%), Gaps = 6/123 (4%)

Query: 564 PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGL--DGPEGDQGPQ 621
           P  PP     PG   P         +   G  G +G +G+      G+  +GP G  GP 
Sbjct: 354 PTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 411

Query: 622 GPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGS 681
           G  G PG    G  G PG+PG  G PG PG  GA G PG   T        GG G K  +
Sbjct: 412 GIMGPPGLQ--GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT 469

Query: 682 RSS 684
            S+
Sbjct: 470 ISA 472


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  534 bits (1376), Expect = e-152
 Identities = 318/700 (45%), Positives = 374/700 (53%), Gaps = 68/700 (9%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA---PGKPGKPGEAGLPGLPGVD 85
            G  GP G PGP G+ G+ G  G  G PG PG  GPKG+   PG PG  GE G  G+ G  
Sbjct: 817  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKP 876

Query: 86   GLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGL---RGPP 141
            G  G+ GP GP+G+ G RG  G PGP G  GG G PGPPGE G  GP G +G    +GPP
Sbjct: 877  GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP 936

Query: 142  GPSGLPGLPGPPGP---------PGPPGHPGVL-PEGATDLQCP-----SICPPGPPGPP 186
            GP G  GLPG PG           GPPG  GV+ P+G T    P        PPGPPG  
Sbjct: 937  GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ 996

Query: 187  GMPGFKGPTGYKGE---QGEVGKDGEKGDPGPPGPAGLPGSVG---LQGPRGLRGLPGPL 240
            G+PG  G  G KG+   QG  GKDG  G  G PG  GLPG+ G   L+G  G +G PGP+
Sbjct: 997  GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1056

Query: 241  GPPGDRGPIGFRGPPGIPGAPGKAGD---RGERGPEGFRGPKGDLGRPG---PKGTPGVA 294
            G PG+RG  G  GP G+PG PG  G     GE+G  G +GP+G  GR G   P G PG A
Sbjct: 1057 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1116

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGE---KGPNGLPGLPGRAGSKGEKGER 351
            GP+G PG  G  G+ G PG  G KG+ G NG PG    +GP G PG+ G  G  G +G++
Sbjct: 1117 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1176

Query: 352  GRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSM 411
            G  G+ G+ G  G PG PG  G+ G  G  G +G  G +GP GPPG PG RG QG  G+ 
Sbjct: 1177 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD 1236

Query: 412  GDPGLPGPQGLRGDVGDRGPGGAAG---PKGDQGIAGSDGLPGDKGELGPSGLVGPKGES 468
            G  G PG  G  G VG++G  G AG   P G+ G+ G  G  G+KGE GP G  GP G  
Sbjct: 1237 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296

Query: 469  GSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGV---------------PGVPGITGKP 513
            G  G+ GPKG  GP G  G  G PG PGP G  GV               PG  G  G P
Sbjct: 1297 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356

Query: 514  GVPGKE----ASEQRIRELCGGMISEQIAQLAAHLRKPLAP-GSIGRPGPAGPPGPPGPP 568
            G PGK     A+    R+   G   E  A+       P+ P G  G+PGP G  G PGP 
Sbjct: 1357 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1416

Query: 569  GSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVP 627
            G  G PGA G  G  GP G  G PG +G+ G +G+KG  G  GL GP G+QG +G +G+P
Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476

Query: 628  GTSKD----GQDGAPGEPGP---PGDPGLPGAIGAQGTPG 660
            GT       G  G PG  GP   PG PGLPG  G +G  G
Sbjct: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1516



 Score =  525 bits (1351), Expect = e-149
 Identities = 320/774 (41%), Positives = 372/774 (48%), Gaps = 147/774 (18%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            G  GP GPPGPPG  G  G DGE GP GLPG  GP+G  G  G PG  G PG+ GVDG  
Sbjct: 616  GERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 675

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGG-KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147
            G  G  GP+G PG  G  G PGP GL G +G  GPPGE G  G PG  GL G  GP G P
Sbjct: 676  GPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP 735

Query: 148  GLPG---------PPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYK 198
            G  G         PPGP GP G+PG       D         G  G  G PGFKG  G K
Sbjct: 736  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 795

Query: 199  GEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP------RGLRGLPGPLGPPGDRGPIGFR 252
            G++GEVG+ G +G+ GP GP G  G  G  GP      +G  G+PG  G PG +GP G  
Sbjct: 796  GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST 855

Query: 253  GPPGIPGA------------PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300
            G PG PGA            PG  G RG  GP G RG +G  G+PGPKGT G  GP G P
Sbjct: 856  GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP 915

Query: 301  GM------------------PGKDGQNGVPGLDGQKGEAG-------------------- 322
            G                   PG  G++G+PG  GQ+GE G                    
Sbjct: 916  GERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 975

Query: 323  -------RNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMP 375
                     G PG  GP G  GLPG AG +G KG+ G  G  G+ GP+G  G PG+ G+P
Sbjct: 976  GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 1035

Query: 376  GERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAA 435
            G +G  G +G  G  GP GP G+PG RG  G  G +G PG PGPQG  G  G++G   A 
Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG---AP 1092

Query: 436  GPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPP 495
            G KG QG AG DG+ G  G  GP+G  G  GE G +GE+G  G +G  G  G  G PGPP
Sbjct: 1093 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1152

Query: 496  GPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP----- 550
            G   LQG  G PGI G  G PG    +        GM  ++  + A     P  P     
Sbjct: 1153 G---LQGPVGAPGIAGGDGEPGPRGQQ--------GMFGQKGDEGARGFPGPPGPIGLQG 1201

Query: 551  -----------GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGY---------RGPTGELG 590
                       G +G  GP GPPGP GP G  G  G +GPPG          +G  GE G
Sbjct: 1202 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1261

Query: 591  DPGPRGN------QGDRGDKGAAGA-------GLDGPEGDQGPQG------------PQG 625
            +PGP G       +G+RG+KG AG        G  GP GD GP+G            P G
Sbjct: 1262 NPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG 1321

Query: 626  VPGTS----------KDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG 669
             PG +          +DG  G PG PGP G+ G PG  G +G PG       QG
Sbjct: 1322 EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1375



 Score =  519 bits (1337), Expect = e-147
 Identities = 307/682 (45%), Positives = 349/682 (51%), Gaps = 88/682 (12%)

Query: 27   RVGLPGPPGP------PGPPGKPGQDGIDGEAGPPG------LPGPPGPKGAPGKPGKPG 74
            R+ L GPPGP      PGP G PG  G  GE+G PG      + GPPGP G PGK G+PG
Sbjct: 524  RIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG 583

Query: 75   E---AGLPGLPGVDGLTGRDGPPG---PKGAPGERGSLGPPGPPG----LGGKGLPGPPG 124
                 G+PG PG  G  G DG PG    KG  GERG  GPPGPPG     G  G  GP G
Sbjct: 584  ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 643

Query: 125  EAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPG 184
              G +GP G +G RG PG  G PG+ G  GPPGP G+ G               P G PG
Sbjct: 644  LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMG---------------PQGEPG 688

Query: 185  PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS---VGLQGPRGLRGLPGPLG 241
            PPG  G  GP G  G QG +G  GEKG  G PG AGLPG+    G  G  G  G  G LG
Sbjct: 689  PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 748

Query: 242  PPGDRGPIGFRGPPGIPGAP---GKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSG 298
            PPG +GPIG+ GP G+ GA    G  G +GE+G +GF G KGD+G  G +G  G  GP G
Sbjct: 749  PPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRG 808

Query: 299  EPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG 358
            E      DG  G  G  G  G+ G +G  GEKG  G+PGLPG  G +G KG  G  G  G
Sbjct: 809  E------DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862

Query: 359  EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPG 418
              G  G  GV G  G  G+RG  G RGS GA GP G P         G KG+ G  G PG
Sbjct: 863  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP---------GPKGTSGGDGPPG 913

Query: 419  PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG 478
            P G RG  G +GP G  GPKG  G  G DGLPG  G+ G +G  G  G  G  G +GP+G
Sbjct: 914  PPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQG 973

Query: 479  TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538
              G  G  G +G PGPPGP G QG+PG  G  G  G PG +    +          +  A
Sbjct: 974  PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK----------DGPA 1023

Query: 539  QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQ 598
             L     +   PG+ G PG  G  GP GPPG +G PG RG  G  GP G  G PGP+G  
Sbjct: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1083

Query: 599  GDRGDKGAAGA----------GLDGPEGDQGPQGPQGVPGTSKD----------GQDGAP 638
            G  G+KGA G           G+ GP G  GP GP G PG   D          G  G  
Sbjct: 1084 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK 1143

Query: 639  GEPGPPGDPGLPGAIGAQGTPG 660
            GE GPPG PGL G +GA G  G
Sbjct: 1144 GENGPPGPPGLQGPVGAPGIAG 1165



 Score =  513 bits (1321), Expect = e-145
 Identities = 319/784 (40%), Positives = 376/784 (47%), Gaps = 168/784 (21%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPG---------------------------PP 61
            G+ GPPGP G PGK G+ G DG  G PG PG                           PP
Sbjct: 565  GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 624

Query: 62   GPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG----LGGK 117
            GP G  G  G+ GE G  GLPG  G  G  GP G  GAPG+ G  G  GPPG    +G +
Sbjct: 625  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 684

Query: 118  GLPGPPGEAGVSGP---PGGIGLRGPP---GPSGLPGLPGPPGPPGPPGHPGVLPEGATD 171
            G PGPPG+ G  GP   PG  G  GPP   GP G PGL G PG  GPPGHPG   EG + 
Sbjct: 685  GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG--KEGQSG 742

Query: 172  LQCPSICPPGPPGP---------------------------PGMPGFKGPTGYKGEQGEV 204
             +  ++ PPGP GP                            G PGFKG  G KG++GEV
Sbjct: 743  -EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 801

Query: 205  GKDGEKGDPGPPGPAGL------PGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIP 258
            G+ G +G+ GP GP G       PG  G  G +G  G+PG  G PG +GP G  G PG P
Sbjct: 802  GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 861

Query: 259  GA------------PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP------ 300
            GA            PG  G RG  GP G RG +G  G+PGPKGT G  GP G P      
Sbjct: 862  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 921

Query: 301  ------------GMPGKDGQNGVPGLDGQKGEA--------------------------- 321
                        G PG  G++G+PG  GQ+GE                            
Sbjct: 922  GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPI 981

Query: 322  GRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEA 381
            G  G PG  GP G  GLPG AG +G KG+ G  G  G+ GP+G  G PG+ G+PG +G  
Sbjct: 982  GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041

Query: 382  GHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQ 441
            G +G  G  GP GP G+PG RG  G  G +G PG PGPQG  G  G++   GA G KG Q
Sbjct: 1042 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK---GAPGEKGPQ 1098

Query: 442  GIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQ 501
            G AG DG+ G  G  GP+G  G  GE G +GE+G  G +G  G  G  G PGPP   GLQ
Sbjct: 1099 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP---GLQ 1155

Query: 502  GVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP----------- 550
            G  G PGI G  G PG    +        GM  ++  + A     P  P           
Sbjct: 1156 GPVGAPGIAGGDGEPGPRGQQ--------GMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207

Query: 551  --GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG 608
              G  G  GP GPPGPPGP G  G  GA GP G  G  G +G  G +G  G+ G+ G  G
Sbjct: 1208 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1267

Query: 609  -AGLDGPEGDQGPQGPQGVPGTS-------KDGQDGAPGEPGP---PGDPGLPGAIGAQG 657
             AG+ GP+G++G +G  G PG +         G DG  G PGP   PGDPG PG  G  G
Sbjct: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1327

Query: 658  TPGI 661
              G+
Sbjct: 1328 QDGV 1331



 Score =  501 bits (1291), Expect = e-142
 Identities = 299/722 (41%), Positives = 354/722 (49%), Gaps = 124/722 (17%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK------- 69
            GE  A   A + G  G  GP GP G  G  G  G+ GP G  G  GP G PG+       
Sbjct: 865  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 924

Query: 70   -----------PGKPGEAGLPGLPGVDGLT---GRDGPPGPKGAP------------GER 103
                       PG PG+ GLPG PG  G T   G+ GPPGP G              GER
Sbjct: 925  GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 984

Query: 104  GSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG 163
            G  GPPGPP  G +GLPG  G+ G  G PG  G+ G  GP+GL G PG  G PG  G PG
Sbjct: 985  GHPGPPGPP--GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG 1042

Query: 164  VL-PEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLP 222
            +   EG          P GPPGP G PG +G  G  G  G  G+ G +G PGP G  G P
Sbjct: 1043 LKGGEG----------PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092

Query: 223  GSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDL 282
            G  G QGP G  G+ GP+G PG  GP          G+PG+ GD+GE G  G +G KGD 
Sbjct: 1093 GEKGPQGPAGRDGVQGPVGLPGPAGP---------AGSPGEDGDKGEIGEPGQKGSKGDK 1143

Query: 283  GRPGPKGTPGVAGPSGEPGMPGKDGQ---NGVPGLDGQKGEAGRNGAPGEKGPNGLPGLP 339
            G  GP G PG+ GP G PG+ G DG+    G  G+ GQKG+ G  G PG  GP GL GLP
Sbjct: 1144 GENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLP 1203

Query: 340  GRAGSKGEKGE---------------------------------RGRAGELGEAGPSGEP 366
            G  G KGE G+                                  G  GE GE G +G P
Sbjct: 1204 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1263

Query: 367  GVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDV 426
            G PG+AG+ G +GE G +G AG  G  GPPGA G  G  G KG+ G  G PG  G  G+ 
Sbjct: 1264 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1323

Query: 427  GDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTS 486
            G  G  G  G KG+ G  G  G PG  GE GP G  G +G  G+ G  G +G +G  G +
Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1383

Query: 487  GVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRK 546
            G +G PG  GP+G QG  G PG  G  G+PG    EQ +                     
Sbjct: 1384 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG-PVGEQGL--------------------- 1421

Query: 547  PLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGA 606
               PG+ G+ GP GP GPPG PG  G PG++G  G+ G  G +G PG +G +GDRG  G 
Sbjct: 1422 ---PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1478

Query: 607  AGA-------GLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGPPGDPGLPGAIGAQGT 658
             G+       G+ GP G  GP GP G+PG     G  G+ G  G  GD GLPG  G+ G 
Sbjct: 1479 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1538

Query: 659  PG 660
            PG
Sbjct: 1539 PG 1540



 Score =  472 bits (1214), Expect = e-133
 Identities = 288/640 (45%), Positives = 317/640 (49%), Gaps = 92/640 (14%)

Query: 28   VGLPGPPGPPGPPGK---------------------PGQDGIDGEAGPPGLPGPPGPKGA 66
            VG PGP GPPGPPGK                     PG  G+ G  GP G  GP G +G 
Sbjct: 927  VGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH 986

Query: 67   PGKPGKPGEAGLPGL---------PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GG 116
            PG PG PGE GLPG          PG  G++G+DGP G +G PGERG  G  G PGL GG
Sbjct: 987  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046

Query: 117  KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-------PEGA 169
            +G  GPPG  G    PG  G  G  GP GLPG PGP GPPGP G  G         P G 
Sbjct: 1047 EGPQGPPGPVG---SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1103

Query: 170  TDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQG 229
              +Q P +  PGP GP G PG  G  G  GE G+ G  G+KG+ GPPGP GL G VG  G
Sbjct: 1104 DGVQGP-VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1162

Query: 230  PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKG 289
              G  G PGP G  G  G  G  G  G PG PG  G +G  GP G +G  GD+G  GP G
Sbjct: 1163 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1222

Query: 290  TPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKG 349
             PG  GP G  G    DG  G PG  G  G  G  G PGE G  G PG  G  G KGE+G
Sbjct: 1223 PPGPRGPQGPNGA---DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1279

Query: 350  ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKG 409
            E+G AG  G AGP G  G PGD G  G  G  G  G  G  G  GP G  GV G +G+ G
Sbjct: 1280 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1339

Query: 410  SMGDPGLPGPQGLRGDVGD---RGPGGAAGPKGDQGI------AGSDGLPGDKGELGPSG 460
              G PG PGP G  G  G    RGP GAAG +G QG       AG++G PG  G +GP G
Sbjct: 1340 DPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1399

Query: 461  LVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK-- 518
              G  G  G RG  GP G QG  G +G  G PGP GP GL G+ G PG  G+ G PG   
Sbjct: 1400 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIG 1459

Query: 519  ------EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG 572
                  E  E+  R L G   S            P A G  G PGPAGP GPPGPPG  G
Sbjct: 1460 LIGPPGEQGEKGDRGLPGTQGS------------PGAKGDGGIPGPAGPLGPPGPPGLPG 1507

Query: 573  HPGARG------------------PPGYRGPTGELGDPGP 594
              G +G                  PPG  GP GE+  P P
Sbjct: 1508 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547



 Score =  444 bits (1142), Expect = e-124
 Identities = 290/684 (42%), Positives = 335/684 (48%), Gaps = 64/684 (9%)

Query: 48   IDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT-------GRDGPPGPKGAP 100
            +DG+ G          +  P  P  P E   PG+P    +T       G  G  G KG P
Sbjct: 374  VDGDLGEYDFYEYKEYEDKPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEP 431

Query: 101  G--ERGSL--GPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPP 156
               E G L  GPPGP G  G  + GPPG  G +GPPG  G RGPPG  GLPG  G PGPP
Sbjct: 432  AVVEPGMLVEGPPGPAGPAG--IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 489

Query: 157  G-----PPGHPGVLPEGATD----------LQCPSICPPGPPGPPGMPGFKGPTGYKGEQ 201
            G     P  + G   +G T           LQ   I   GPPGP G+ G  GP G  G  
Sbjct: 490  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 549

Query: 202  GEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAP 261
            G  G+ G+ G  GP G  G PG  G  G RG  G  G  G PG+ G  G RG  G+PG P
Sbjct: 550  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 609

Query: 262  GKAGDRGERGPEGFRGPKGD------LGRPGPKGTPGVA------GPSGEPGMPGKDGQN 309
            G  G RGERGP+G  GP GD       G  GP+G PG A      GP G PG PG+ G  
Sbjct: 610  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669

Query: 310  GVPGLDGQKGEAGRNGAP------GEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPS 363
            GV G  G KG  G  G P      G  GP GLPG  G  G  GEKG +G+ G  G  G  
Sbjct: 670  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729

Query: 364  GEPGVPGDAGMPGERGEAGHRGSAGAL---GPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420
            G PG PG  G  GE+G  G  G  G +   GP+G  GA GVRG +G KG  G+ G PG +
Sbjct: 730  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789

Query: 421  GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480
            G  G  GDRG  G  GP+G+ G  G  G  G  G+ GPSG  G KG+ G  G  G  G Q
Sbjct: 790  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 849

Query: 481  GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG-----GMISE 535
            GP G++G  G PG  G  G +GV G PG  G+ G  G   S +  R   G     G    
Sbjct: 850  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGS-RGARGPTGKPGPKGTSGG 908

Query: 536  QIAQLAAHLRKPLAP-GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGP 594
                     R P  P G +G PGP GPPGPPG  G  GHPG RG  G++G TG  G  G 
Sbjct: 909  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968

Query: 595  RGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIG 654
             G QG  G+ G  G    G  G  GP G QG+PG +  G++GA G+PGP G  G  G  G
Sbjct: 969  VGPQGPTGETGPIGE--RGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAG 1024

Query: 655  AQGTPGICDTSACQGA--VLGGVG 676
             +G PG       QGA  + GG G
Sbjct: 1025 LRGFPGERGLPGAQGAPGLKGGEG 1048



 Score =  426 bits (1095), Expect = e-119
 Identities = 246/543 (45%), Positives = 291/543 (53%), Gaps = 53/543 (9%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            GE  +A  A  +GLPG PGP GPPG  G+ G  GE GP G   P G  G  G  G PG A
Sbjct: 1060 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG---PAGRDGVQGPVGLPGPA 1116

Query: 77   GLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL----------GGKGLPGPPGEA 126
            G  G PG DG  G  G PG KG+ G++G  GPPGPPGL          GG G PGP G+ 
Sbjct: 1117 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1176

Query: 127  GVSGPPGGIGLRG---PPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGP 182
            G+ G  G  G RG   PPGP GL GLPGPPG  G  G  G + P G          PPGP
Sbjct: 1177 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG----------PPGP 1226

Query: 183  PGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGP 242
             GP G  G  GP G  G  G VG  GEKG+PG  G  G PG  G+ GP+G RG  G  GP
Sbjct: 1227 RGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGP 1286

Query: 243  PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGM 302
            PG  GP G +GPPG            + GP+G  GP G  G PGP G PG AG  G  G 
Sbjct: 1287 PGAAGPPGAKGPPG------------DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1334

Query: 303  PGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG------RAGE 356
             G+DG  G PG  G  GEAG  G PG++GP G  G  GR G KG KGE G      + G 
Sbjct: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394

Query: 357  LGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA---LGPQGPPGAPGVRGFQGQKGSMGD 413
            +G  GP+G+PG  G  G+PG  GE G  G+AG     GP GPPG PG++G  G KG  G 
Sbjct: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1454

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL---GPSGLVGPKGESGS 470
            PGL G  G  G+ G++G  G  G +G  G  G  G+PG  G L   GP GL GP+G  G+
Sbjct: 1455 PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1514

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-SEQRIRELC 529
            +G  GP G +G +G  G  G PGPPG + +Q +P +     +    G +A ++  I +  
Sbjct: 1515 KGSTGPAGQKGDSGLPGPPGSPGPPGEV-IQPLPILSSKKTRRHTEGMQADADDNILDYS 1573

Query: 530  GGM 532
             GM
Sbjct: 1574 DGM 1576



 Score =  124 bits (312), Expect = 2e-28
 Identities = 72/145 (49%), Positives = 77/145 (53%), Gaps = 20/145 (13%)

Query: 16   LGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE 75
            +GE      A + G PGP GPPG PG  G  G  GE G PGL G  GP   PG+ G+ G+
Sbjct: 1416 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP---PGEQGEKGD 1472

Query: 76   AGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
             GLPG  G  G  G  G PGP       G LGPPGPP     GLPGP       GP G  
Sbjct: 1473 RGLPGTQGSPGAKGDGGIPGP------AGPLGPPGPP-----GLPGP------QGPKGNK 1515

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPG 160
            G  GP G  G  GLPGPPG PGPPG
Sbjct: 1516 GSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 42/123 (34%), Positives = 51/123 (41%), Gaps = 6/123 (4%)

Query: 564 PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGL--DGPEGDQGPQ 621
           P  PP     PG   P         +   G  G +G +G+      G+  +GP G  GP 
Sbjct: 393 PTSPPNEEFGPGV--PAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 450

Query: 622 GPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGS 681
           G  G PG    G  G PG+PG  G PG PG  GA G PG   T        GG G K  +
Sbjct: 451 GIMGPPGLQ--GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT 508

Query: 682 RSS 684
            S+
Sbjct: 509 ISA 511


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  532 bits (1371), Expect = e-151
 Identities = 307/694 (44%), Positives = 355/694 (51%), Gaps = 61/694 (8%)

Query: 28   VGLPGPPGPPGP---------PGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGL 78
            VG PGP GPPG          PGK G+ G  G AG  G PGP GP+G PG PG PG  G 
Sbjct: 924  VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG- 982

Query: 79   PGLPGVDGLTGRDGPPGP--------------------------KGAPGERGSLGPPGPP 112
             G  G  GL G  G PGP                          +GAPG  GS G  G P
Sbjct: 983  KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDP 1042

Query: 113  GLGGKGLPGPPGEAGVSGPPGGIGLRG---PPGPSGLPGLPGPPGPPGPPGHPGV---LP 166
            G+G  G PGP G  G  G PG  GL G   P GP+G  G PG PG  GPPG PG+   L 
Sbjct: 1043 GIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS 1102

Query: 167  EGATDLQCPSICPPGPPGPPG---MPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG 223
             G  +L    +C   PPGPPG   +PGFKG  G  G+ G  G +G+KG+ GPPG  G PG
Sbjct: 1103 PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG 1162

Query: 224  SVGLQGPRGLRGLPGPLGPPGDR---GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKG 280
              G QG +G RG  G +G  GD+   G  GF GPPG PG PG  G  G  GP G +    
Sbjct: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ---- 1218

Query: 281  DLGRPGPKGTPGVAGPSGEPGMP---GKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPG 337
              G PG +G PG  GPSG PG+P   GK+G++G PG  G+ G+AG  G PG +G  G PG
Sbjct: 1219 --GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276

Query: 338  LPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPG 397
              G  G  G  G RG +G +G  G  G PG  GD G  G +G  G RG  G  G  G PG
Sbjct: 1277 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 1336

Query: 398  APGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELG 457
             PG  G  GQKGS G+ G PG  G  G  G  G  G  G  G +G+ G  G PG KGE G
Sbjct: 1337 EPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396

Query: 458  PSGLVGPKGESGSRGELGPKGTQGPNGTSGV---QGVPGPPGPLGLQGVPGVPGITGKPG 514
              G+ G KG  G +G+ G  G  G  G +G+   QG+PG  GP+G  G PG PG  G  G
Sbjct: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456

Query: 515  -VPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGH 573
              P  E   + I+E  G  +  ++A L A +       S GRPGP GPPG  G PG  G 
Sbjct: 1457 ESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGP 1516

Query: 574  PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDG 633
             G  G PG  G  G  G  GP+G +G +GD GA G GL G  G  G  G  G PG +KDG
Sbjct: 1517 MGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDG 1576

Query: 634  QDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSAC 667
              G PG  G  G  G PG  G  G PG CD S C
Sbjct: 1577 LPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQC 1610



 Score =  512 bits (1319), Expect = e-145
 Identities = 340/828 (41%), Positives = 390/828 (47%), Gaps = 212/828 (25%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAG----------- 77
            G+ G PG  G PG PG+ G+ G  GPPGLPGPPG  GAPG  G+ GE G           
Sbjct: 548  GMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLD 607

Query: 78   -LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL--------------------GG 116
              PG PG  G  GR GP G  G  GE+G +GP GPPG+                    G 
Sbjct: 608  GFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGH 667

Query: 117  KGLPGPPGEAGV------SGPPGGIGLR------GPPGPSGLPGLPGPPGPPGPPGHPGV 164
            +G PGPPG  G        GPPG  GLR      GPPG  GL GL GPPGPPG PG PG 
Sbjct: 668  QGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG- 726

Query: 165  LPEGATDLQCPSICP--PGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLP 222
             P G+  L      P  PGPPGP G PG  GP G  G  G  G+ GE+G+ G PG  GL 
Sbjct: 727  -PGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLR 785

Query: 223  GSVGLQ------GPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGP---- 272
            G +G Q      G +G  GLPG  G PG RG  G +G  G  G PG  GDRGE+G     
Sbjct: 786  GEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 845

Query: 273  ------------------EGFRGPKGDLGRPGPKGTPGV---------AGPSGEPGMPGK 305
                               G +GPKG+ G PG  G PG+          GP+G PG  G+
Sbjct: 846  GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ 905

Query: 306  DGQNGVPGLDGQKGEAGRNGAPGEKGPN---GLPGLPGRAGSKGEKGERGRAGELGEAGP 362
            +G +G PG  G  G  G  GAPG  GP    G PGL G  G  GE+GE+G AGE G  GP
Sbjct: 906  EGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP 965

Query: 363  SGEPGVPGDAGMP-----GERGEAGHRGSAGALGPQGPPGAPG-VRGFQ-----GQ--KG 409
             G  G PG  G+P     G+ GE G RGS G  GP G   A G VRG +     GQ  KG
Sbjct: 966  VGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKG 1025

Query: 410  SMGDPGLPGPQGLRGD--VGDRGPGGAAGPKGD---------------QGIAGSDGLPGD 452
              G PG+PG  G RGD  +G  GP G +GP GD               QG AG DG PG+
Sbjct: 1026 DRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN 1085

Query: 453  KGELGP---------------------------------SGLVGPKGESGSRGELGPKGT 479
             GE GP                                  GL G KG+ G  G+ G +GT
Sbjct: 1086 PGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGT 1145

Query: 480  QGPNGTSGVQGVPGPPGPLGLQGV------------------PGVPGITGKPGVPGKEAS 521
            +G  G +G  G+PGPPG  G QG                   PGVPG  G PG PG    
Sbjct: 1146 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG- 1204

Query: 522  EQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP------------------PG 563
                        ++ IA  A       +PG  G PGP GP                  PG
Sbjct: 1205 ------------ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPG 1252

Query: 564  PPGPPGSIGHP------GARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA----GLDG 613
            PPG PG  G P      GARGPPG++G TG+ G PGPRG  G  G  G  G     G  G
Sbjct: 1253 PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTG 1312

Query: 614  PEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
            P G QGPQGP+G PG  K+G  G+PGEPGP G PG  G+ G  G+PG+
Sbjct: 1313 PTGPQGPQGPRGPPG--KNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 1358



 Score =  501 bits (1290), Expect = e-142
 Identities = 318/741 (42%), Positives = 361/741 (48%), Gaps = 131/741 (17%)

Query: 31   PGPPGPPGPPGKPGQDGID-----------------GEAGPPGLPGPPGPKGAPGKPGKP 73
            P PP PP  P  PG + I                  G AGP GLPGP G  GA G  G P
Sbjct: 451  PPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAP 510

Query: 74   GEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPP 132
            G  G  G  G+       GP G +G  GE+GSLG PGPPG  G KG+ G PGE G  G P
Sbjct: 511  GPKGEKGDVGI-------GPFG-QGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLP 562

Query: 133  GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192
            G +G+RGP GP   PGLPGPPG  G PG  G   E  T  +       G  G PG PG  
Sbjct: 563  GEVGMRGPQGP---PGLPGPPGRVGAPGLQGERGEKGTRGEKGE---RGLDGFPGKPGDT 616

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSV-------GLQGPRGLRGLPGPLGPPGD 245
            G  G  G  G  G  GEKGD GP GP G+PGSV       G QG  G RG  G  GPPG 
Sbjct: 617  GQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGA 676

Query: 246  RGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGK 305
            RGPIG  G  G PG  G  G +G+ GP G  G  G  G PGP G PG  GP G PG+PG+
Sbjct: 677  RGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGE 736

Query: 306  ---------DGQNGVPGLDGQK---GEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGR 353
                      G  G PG DG     G  G  G PGE+G +GLPG PG  G  GE+G  GR
Sbjct: 737  IGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGR 796

Query: 354  AGELGEAGPSGEPGVPGDAGMPGERGEAGH---------RGSAGALGPQGPPGAPG---- 400
             GE GEAG  G PG PG  G  G++GE G          RG  G  GP GPPG PG    
Sbjct: 797  PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 856

Query: 401  ------VRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQ---------GIAG 445
                  + G QG KG  GDPGLPG  GL+G  G+ GP G  GP G +         G AG
Sbjct: 857  FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAG 916

Query: 446  SDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPG 505
            + G PG  G  GPSG  G  G  G RG  G  G +G  G +G +G PGP GP G  G PG
Sbjct: 917  NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976

Query: 506  V-----------PGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRK-------- 546
            +           PG+ G PG+PG   +    +  CG +   +   L     K        
Sbjct: 977  LPGPPGKGKDGEPGLRGSPGLPGPLGT----KAACGKVRGSENCALGGQCVKGDRGAPGI 1032

Query: 547  PLAPGSIGRP--GPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDK 604
            P +PGS G P  G AGPPGP GPPG  G PG+RG PG+ GP G  G  G  GN G+RG  
Sbjct: 1033 PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPP 1092

Query: 605  GAAG-------------------------AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPG 639
            G  G                          GL G  G +G +G  G PG  ++G +G  G
Sbjct: 1093 GKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG--REGTEGKKG 1150

Query: 640  EPGPPGDPGLPGAIGAQGTPG 660
            E GPPG PG PG  G QG+ G
Sbjct: 1151 EAGPPGLPGPPGIAGPQGSQG 1171



 Score =  501 bits (1289), Expect = e-141
 Identities = 326/834 (39%), Positives = 377/834 (45%), Gaps = 218/834 (26%)

Query: 28   VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPG------------- 74
            +G PG PGPPGP G PG+DG +G  GPPG  G PG +G  G PGKPG             
Sbjct: 737  IGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGR 796

Query: 75   -----EAGLPGLPGVDGLTGRDGP---------PGPKGAPGERGSLGPPGPPGLGG---- 116
                 EAGLPG PG  G+ G  G          PG KG  GE+G  GP GPPGL G    
Sbjct: 797  PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 856

Query: 117  ----------------KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPG 160
                            KG PG PGE G+ G PG +G +GP GP G  G  G  G PG  G
Sbjct: 857  FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAG 916

Query: 161  HPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAG 220
            +PG        +  P   P GPPG  G PG +G  G  GE+GE G  GE+G PGP GP G
Sbjct: 917  NPGA----PGHVGAPG--PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRG 970

Query: 221  LPGSVGLQGP-----------RGLRGLPGPLGP--------------------------- 242
             PG+ GL GP           RG  GLPGPLG                            
Sbjct: 971  DPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAP 1030

Query: 243  -----PGDRGP--IGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAG 295
                 PG RG   IG  GPPG  G PG  G  G RG  GF GP+G  GR G  G PG  G
Sbjct: 1031 GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERG 1090

Query: 296  PSGEPGM---------------------PGKDGQNGVPGLDGQKGEAGR------NGAPG 328
            P G+PG+                     PG  G  G+PG  G KG  G+       G  G
Sbjct: 1091 PPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 1150

Query: 329  EKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAG 388
            E GP GLPG PG AG +G +GERG  GE+G+ G  G PGVPG  G PG  G  G  G AG
Sbjct: 1151 EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 1210

Query: 389  ALGP---------------QGPPGAPGVRGFQGQKG------------SMGDPGLPGPQG 421
            A GP               QGP G PG+ G +G++G              G+PGLPGP+G
Sbjct: 1211 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 1270

Query: 422  LRGDVGDRG---PGGAAGPKGDQG---IAGSDGLPGDKGELGPSGLVGPKG--------- 466
             RG  G +G     GA GP+G+ G   + G +GLPG  G+ GP+G  GP+G         
Sbjct: 1271 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 1330

Query: 467  ESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPG---ITGKPGVPGKEASEQ 523
              GS GE GP GT G  G+ G  G PG PG LG +G PG PG   + GK GVPGK     
Sbjct: 1331 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP- 1389

Query: 524  RIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYR 583
                   G   E+          P   G  G PG  G PG PG PG  GH G  GP G  
Sbjct: 1390 -------GFKGER--------GDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP 1434

Query: 584  GPTGELGDPGPRGNQGDRGDKGAA--------------GAGLDGP-------------EG 616
            G  G +G PGP G  G  G +G +              G  L+               + 
Sbjct: 1435 GENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKS 1494

Query: 617  DQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGA 670
             QG  GP G PG     +DG PG  GP G+PG PG  G +G  G       +GA
Sbjct: 1495 SQGRPGPPGPPG-----KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGA 1543



 Score =  408 bits (1048), Expect = e-113
 Identities = 242/590 (41%), Positives = 279/590 (47%), Gaps = 107/590 (18%)

Query: 24   GAQRVGLPGPPGPPGPPGK---------PGQDGIDGEAGPPGLPGPPGPKGAPGKPG--- 71
            G   +G+ GPPGP GPPG          PG  G  G AG  G PG PG +G PGKPG   
Sbjct: 1040 GDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSS 1099

Query: 72   ------------------KPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG 113
                               PG  GLPGLPG  G  G  G PG +G  G++G  GPPG PG
Sbjct: 1100 LLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPG 1159

Query: 114  LGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQ 173
                G+ GP G  G  G  G +G +G  G  G+PG  GPPG PGPPG  G+         
Sbjct: 1160 --PPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGP--- 1214

Query: 174  CPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGL 233
             P I   G PG  G PG +GP+G  G  GE GK+G  G PGPPG  G  G  GL GP G 
Sbjct: 1215 -PGI--QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA 1271

Query: 234  RGLPG------PLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP 287
            RG PG        G PG RG  G  G PG  G PGK GD G  GP+G +GP+G  G+ G 
Sbjct: 1272 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 1331

Query: 288  KGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE 347
             G+PG  GPSG PG  G  G+NG PGL G  G  G  G PGEKG  G  G+PG+ G  G 
Sbjct: 1332 PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 1391

Query: 348  KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA------LGPQGPPGAPGV 401
            KGERG  G  G+ GP G  G PGD G+PG +G  G  G  G       +GP GPPG PG 
Sbjct: 1392 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGF 1451

Query: 402  RGFQGQKGSM--------------------------------------GDPGLPGPQGLR 423
             G +G+  SM                                      G PG PG  GL 
Sbjct: 1452 PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 1511

Query: 424  GDVGD------------RGPGGAAGPKGDQGIAGSDGLPGD--KGELGPSGLVGPKGESG 469
            G  G              GP G  GPKG++G  G  G PG   +GE+GP G+ G  GE G
Sbjct: 1512 GRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1571

Query: 470  SR-----GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPG 514
                   G  GP+G  GP G  G+ G PGPPG            +  +PG
Sbjct: 1572 YAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621



 Score =  392 bits (1006), Expect = e-109
 Identities = 260/644 (40%), Positives = 310/644 (48%), Gaps = 101/644 (15%)

Query: 58   PGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK 117
            P PP P   P +P  PG   +  L  ++          P G  GE G  GP         
Sbjct: 451  PPPPPP---PQRPPTPGSEQIGFLKTINCSC-------PAGEKGEMGVAGP--------M 492

Query: 118  GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSI 177
            GLPGP G+ G  GP G  G +G  G  G+    GP G  G  G  G L            
Sbjct: 493  GLPGPKGDIGAIGPVGAPGPKGEKGDVGI----GPFGQ-GEKGEKGSL------------ 535

Query: 178  CPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLP 237
               G PGPPG  G KG  G  GE GE G  GE G  GP GP GLPG  G  G  GL+G  
Sbjct: 536  ---GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGER 592

Query: 238  GPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGP- 296
            G  G  G++G    RG  G PG PG  G +G  GP G  GP+G+ G  GP G PGV G  
Sbjct: 593  GEKGTRGEKGE---RGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSV 649

Query: 297  ------SGEPGMPGKDGQNGVPGLDGQKGEAG---RNGAPG------EKGPNGLPGLPGR 341
                   GE G PG  G  G PG  G +G  G   R+G PG      +KG  G PG+PG 
Sbjct: 650  VQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGL 709

Query: 342  AGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV 401
             G +G  G  G  G     GP G PG+PG+ G PG+ G  G  G  G  GP GPPG PG 
Sbjct: 710  LGLQGPPGPPGVPGP---PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT 766

Query: 402  RGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPG------DKGE 455
            +G  G++G   + GLPG  GLRG++G++G  G  G KG+ G+ G+ G PG      D+GE
Sbjct: 767  KGEPGERG---EDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE 823

Query: 456  LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGV----QGVPGPPGPLGLQGVPGVPGITG 511
             G  GL G KG+ G +GE GP G  G  GT+ +      +PG  GP G +G PG+PG  G
Sbjct: 824  KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 883

Query: 512  KPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSI 571
              G PG E   Q      G        Q  AH   P A G+ G PG  G PGP GPPGS+
Sbjct: 884  LQGRPG-ELGPQGPTGPPGAK-----GQEGAH-GAPGAAGNPGAPGHVGAPGPSGPPGSV 936

Query: 572  GHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTS 630
            G PG RG PG                 G+RG+KGAAG  G  GP G +G  G  G+PG  
Sbjct: 937  GAPGLRGTPG---------------KDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPP 981

Query: 631  KDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGG 674
              G+DG PG     G PGLPG +G +   G       +   LGG
Sbjct: 982  GKGKDGEPGL---RGSPGLPGPLGTKAACG--KVRGSENCALGG 1020



 Score =  334 bits (857), Expect = 1e-91
 Identities = 215/548 (39%), Positives = 242/548 (44%), Gaps = 122/548 (22%)

Query: 25   AQRVGLPGPPGPPGPPGKPGQDGI---------------DGEAGPPGLPGPPG---PKGA 66
            A R G PG PG  GPPGKPG   +               D   GPPGLPG PG    KG 
Sbjct: 1077 AGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGV 1136

Query: 67   PGKPG------KPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP 120
            PGKPG      K GEAG PGLPG  G+ G  G  G +GA GE G  G  G PG+   G  
Sbjct: 1137 PGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGV--PGFM 1194

Query: 121  GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP 180
            GPPG  G  G  G  G  GPPG  G PG  GPPGP GP G PG+  E   + +     PP
Sbjct: 1195 GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP 1254

Query: 181  GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAG---LPGSVGLQGPRGLRGLP 237
            G PG  G PG  GP G +G  G  G  G+ G PGP G +G   LPG  GL G  G  G  
Sbjct: 1255 GEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPT 1314

Query: 238  GPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEG---------FRGPKGDLGRPGPK 288
            GP GP G RGP G  G PG PG PG +G  G++G +G         F GP+G  G PG K
Sbjct: 1315 GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEK 1374

Query: 289  GTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPG-------------------- 328
            G PG  G  G+PG PG  G+ G PG+ G KG  G  G PG                    
Sbjct: 1375 GVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP 1434

Query: 329  -EKGPNGLPGLPGRAGSKGEKGER------------------------------------ 351
             E GP G PG PG+ G  G +GE                                     
Sbjct: 1435 GENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKS 1494

Query: 352  -----------GRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGA-- 398
                       G+ G  G AGP GEPG PG  G+ G  G  G +G  GA G  G PG   
Sbjct: 1495 SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGL 1554

Query: 399  ------PGVRGFQGQKGSMGD--PGLPGPQGLRGDVGDRG------PGGAAGPKGDQGIA 444
                  PG+ G  G+ G   D  PG+PGPQG  G  G  G      P G   P      A
Sbjct: 1555 RGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFA 1614

Query: 445  GSDGLPGD 452
                 PG+
Sbjct: 1615 SLAARPGN 1622



 Score =  118 bits (295), Expect = 2e-26
 Identities = 69/146 (47%), Positives = 75/146 (51%), Gaps = 22/146 (15%)

Query: 12   LLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPG 71
            L  LL ++  A      G PGPPGPPG  G PG+ G  GE G PG  G  GP G  G  G
Sbjct: 1480 LAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKG 1539

Query: 72   KPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGP 131
            + G  G PG PGV GL G  GPPG  G PGE         PG    GLPG PG       
Sbjct: 1540 ERGAKGDPGAPGV-GLRGEMGPPGIPGQPGE---------PGYAKDGLPGIPGP------ 1583

Query: 132  PGGIGLRGPPGPSGLPGLPGPPGPPG 157
                  +G  GP+G PGLPGPPGPPG
Sbjct: 1584 ------QGETGPAGHPGLPGPPGPPG 1603


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  532 bits (1370), Expect = e-151
 Identities = 331/788 (42%), Positives = 375/788 (47%), Gaps = 138/788 (17%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            G  G PG  G  G+PG  G  GEAG PG+PG  G  G  G PG+PG  GLPG  G  G  
Sbjct: 429  GGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAP 488

Query: 89   GRDGPPGPKGAPGE------RGSLGPPGPPGLGGK----GLPGPPGEAGVSGPPGG---I 135
            G  GP GP G PGE      RG+ GP GP G  G+    G+PG PG  G+ G PGG    
Sbjct: 489  GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSD 548

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVL----PEG--ATDLQCPSICPPGPPGPPGMP 189
            G  GPPG  G  G PGPPGP GP G PGV+    P+G      +      PG PGP G P
Sbjct: 549  GKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP 608

Query: 190  GFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPI 249
            G  G TG +G  G  G  G+KGD GPPGP GL G  G  GP G  G PG  GP GD G  
Sbjct: 609  GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP 668

Query: 250  GF------------RGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGV---- 293
            G             RGPPG+ GAPG  G  G  GPEG +G  G  G PG  GTPG+    
Sbjct: 669  GAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMP 728

Query: 294  --------AGPSGEPGMPGKDGQNGVPGLDGQKGEA------GRNGAPGEKGPNGLPGLP 339
                     GP G+ G PG  G +GVPG DG +G        G  G PG+KG  G PGLP
Sbjct: 729  GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLP 788

Query: 340  GRAGSKGEKGERGRAGELGEA------GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQ 393
            G AG +G  GERG  G  G A      G +GEPG  G+ G PGE+GE G  G AG  G  
Sbjct: 789  GIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGS 848

Query: 394  GPPGAPGVRGFQGQKGSMGDP---------GLPGPQGLRGDVGDRGPGGAAGPKGDQGIA 444
            GP G PG +G +G++GS G P         GLPGP G  G+ G  GP G+ G  G  G A
Sbjct: 849  GPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPA 908

Query: 445  GSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGV------PGPPGPL 498
            G+ G PG  G  GP G  G  GE GS G  GP G  GP G +G+ G       PG PGP 
Sbjct: 909  GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968

Query: 499  GLQGVPGVPGITGKPGVPGKEASE-----QRIRELCG--------------GMISEQIAQ 539
            G  G  GV G +GKPG  G          Q +  L G              G+     + 
Sbjct: 969  GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSP 1028

Query: 540  LAAHLR----KPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPR 595
                 R     P APG+ G PGP GP GP G  G  G  G  GP G  GP G  G PGP+
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ 1088

Query: 596  GNQGDRGDKGAAGA----------------------------GLDGPEGDQGPQGPQGVP 627
            G +GD+G+ G  GA                            G  GP G +GP GP G P
Sbjct: 1089 GPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP 1148

Query: 628  GTSKDGQDGAPGEPGP---------------PGDPGLPGAIGAQGTPGICDTSACQGAVL 672
            G  KDG  G PG  GP               PG PG PG  G  G PG C       A+ 
Sbjct: 1149 G--KDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIA 1206

Query: 673  GGVGEKSG 680
            G  GEK+G
Sbjct: 1207 GIGGEKAG 1214



 Score =  526 bits (1355), Expect = e-149
 Identities = 315/683 (46%), Positives = 351/683 (51%), Gaps = 59/683 (8%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK---PGKPGEAGLPGLPGVD 85
           G PGP GPPGPPG PG  G  G  G PG  GPPG  G  G    PG PG  G  G  G D
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKD 230

Query: 86  GLTGRDGPPGPKGAPGERGSLGPPGPPGLGG----KGLPGPPGEAGVSGPPGGIGLRGPP 141
           G +GR G PG +G PG  G  GP G PG  G    +G  G  GE G +G PG  G  G P
Sbjct: 231 GESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLP 290

Query: 142 GPSGLPGLPGPPGPPGPPGHPGVLPEGA----TDLQCPSICPPGPPGPPGMPGFKGPTGY 197
           G +G PG  GP G PG  G PG LP  A     D    S   PGPPGPPG  GF G  G 
Sbjct: 291 GENGAPGPMGPRGAPGERGRPG-LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGA 349

Query: 198 KGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGI 257
           KGE G  G  G  G PG  G  G  G  G QGP      PGP G  G  G  G  GP GI
Sbjct: 350 KGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP------PGPPGINGSPGGKGEMGPAGI 403

Query: 258 PGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQ 317
           PGAPG  G RG  GP G  G     G  G  G PG  G  GEPG  G+ G+ G+PG+ G 
Sbjct: 404 PGAPGLMGARGPPGPAGANGAP---GLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460

Query: 318 KGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGE 377
           KGE G++G+PGE G NGLP         G  GERG  G  G AGP+G PG  G AG  G 
Sbjct: 461 KGEDGKDGSPGEPGANGLP---------GAAGERGAPGFRGPAGPNGIPGEKGPAGERGA 511

Query: 378 RGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGP 437
            G AG RG+AG  G  G PG PG+RG  G  G  G  G PGP G +G+ G  GP G +GP
Sbjct: 512 PGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGP 571

Query: 438 KGDQGI------AGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGV 491
           +G  G+       G+DG PG  GE G  G  GP+G  G  GE GP+G  GP G  G +G 
Sbjct: 572 RGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGD 631

Query: 492 PGPPGPLGLQGVPGV---PGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPL 548
            GPPGP GLQG+PG    PG  GKPG PG +          G    +  A        P 
Sbjct: 632 TGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD----AGAPGAPGGKGDAGAPGERGPPG 687

Query: 549 APGSIGRPGPAGPP---------GPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQG 599
             G+ G  G AGPP         GPPGPPG+ G PG +G PG R   G LG PGP+G++G
Sbjct: 688 LAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGER---GGLGSPGPKGDKG 744

Query: 600 DRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKD-GQDGAPGEPGPPGDPGLPGAIGAQG 657
           + G  GA G  G DGP G  GP GP G  G   D G+ GAPG PG  G  G PG  G  G
Sbjct: 745 EPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG 804

Query: 658 TPGICDTSAC--QGAVLGGVGEK 678
            PG         Q    GG GE+
Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGER 827



 Score =  516 bits (1330), Expect = e-146
 Identities = 309/702 (44%), Positives = 354/702 (50%), Gaps = 63/702 (8%)

Query: 19   LLAAAGAQ-RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAG 77
            L  AAGA+   G  G  G PGPPG PG  G  G    PG  G  GP G+PG  G PG+ G
Sbjct: 313  LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGS---PGAKGEVGPAGSPGSNGAPGQRG 369

Query: 78   LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGG-KGLPGPPGEAGVSGPPGGIG 136
             PG  G  G  G  GPPG  G+PG +G +GP G PG  G  G  GPPG AG +G PG  G
Sbjct: 370  EPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRG 429

Query: 137  LRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPP------GMPG 190
              G PG +G  G PGP G  G  G PGV      D +  S   PG  G P      G PG
Sbjct: 430  GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPG 489

Query: 191  FKGPTGYKGEQGEVGKDGEKGDPGPPGP---AGLPGSVGLQGPRGLRGLPGPLGPPGD-- 245
            F+GP G  G  GE G  GE+G PGP GP   AG PG  G+ G  G+RG+PG  G PG   
Sbjct: 490  FRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDG 549

Query: 246  -RGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPG 304
              GP G +G  G PG PG +G RG+ G  GF GPKG+ G PG  G  G  G  G  G PG
Sbjct: 550  KPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPG 609

Query: 305  KDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSG 364
            K+G+ G  G  G  G  G  G  G  GP GL GLPG  G  GE G+ G  G  G+AG  G
Sbjct: 610  KNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPG 669

Query: 365  EPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG 424
             PG  GDAG PGERG  G  G+ G  G  GPPG  G +G  G  G  G  G PG QG+ G
Sbjct: 670  APGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPG 729

Query: 425  DVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGP------KG 478
            + G  G  G  G KG+ G  G+DG+PG  G  GP+G +GP G +G  G+ G        G
Sbjct: 730  ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPG 789

Query: 479  TQGPNGTSGVQGVPGPPGPLGLQGVP---------------------GVPGITGKPG--V 515
              GP G+ G +G  GPPGP G  G P                     G PG+ G PG   
Sbjct: 790  IAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG 849

Query: 516  PGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP---PGPPGPPGSIG 572
            P      Q ++   G       A        P  PGS G PGP GP   PG  GPPG  G
Sbjct: 850  PAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAG 909

Query: 573  HPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG----------AGLDGPEGDQGPQ- 621
            + GA G PG  GP G+ G PG +G+ G +G  GA G           GL GP G  GP+ 
Sbjct: 910  NTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRG 969

Query: 622  --GPQGVPGTS-KDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
              GPQGV G S K G +G  GE GPPG  GLPG  G  G PG
Sbjct: 970  SPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011



 Score =  452 bits (1162), Expect = e-127
 Identities = 264/579 (45%), Positives = 296/579 (51%), Gaps = 59/579 (10%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGL------P 82
            GLPG  GPPG  GKPG+ G  G+AG PG PG  G  GAPG+ G PG AG PGL      P
Sbjct: 642  GLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP 701

Query: 83   GVDGLTGRDGPPGPKGA---------PGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPG 133
            G +G  G  GPPGP GA         PGERG LG PGP G   KG PG PG  GV G  G
Sbjct: 702  GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKG--DKGEPGGPGADGVPGKDG 759

Query: 134  GIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKG 193
              G  GP GP G  G PG  G  G PG PG+     +  +     PPGP G PG PG  G
Sbjct: 760  PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNG 819

Query: 194  PTGYKGEQGEVGKDGEKGDPG---PPG---PAGLPGSVGLQGPRG------------LRG 235
              G KGE+G  G+ GE G PG   PPG   PAG PG  G++G RG             RG
Sbjct: 820  EPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARG 879

Query: 236  LPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAG 295
            LPGP G  G+ GP G  G PG  G PG AG+ G  G  G  GPKGD G+PG KG+PG  G
Sbjct: 880  LPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG 939

Query: 296  P------------------SGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPG 337
            P                  +G PGMPG  G  G  G+ G+ G+ G NG  GE+GP G  G
Sbjct: 940  PPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG 999

Query: 338  LPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPG 397
            LPG AG+ GE G  G  G  G  G  G PG  GD G  G  G  G  G  G  GP GP G
Sbjct: 1000 LPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAG 1059

Query: 398  APGVRGFQGQKGSMGDPG------LPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPG 451
              G RG  G  G  G PG       PGPQG RGD G+ G  GAAG KG +G  G+ G PG
Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPG 1119

Query: 452  DKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITG 511
              G  G  G +G  G +G RG +GP G  G +GTSG  G  GPPGP G +G  G  G  G
Sbjct: 1120 SPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPG 1179

Query: 512  KPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP 550
             PG PG           CGG+ +  IA +        AP
Sbjct: 1180 HPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218



 Score =  419 bits (1076), Expect = e-117
 Identities = 261/616 (42%), Positives = 296/616 (48%), Gaps = 112/616 (18%)

Query: 122 PPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPG 181
           PP   G  GP G  G  G PG +G PG+PG PG PG PG PG+         C S CP G
Sbjct: 98  PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGI---------CES-CPTG 147

Query: 182 PPGPP---------------GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVG 226
           P                   G+ G+ GP G  G  G  G  G  G PG PG  G PG  G
Sbjct: 148 PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPG 207

Query: 227 LQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPG 286
             GP G      P GPPG  GP G  G  G  G PG+ G+RG  GP G +GP G  G PG
Sbjct: 208 QAGPSG------PPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPG 261

Query: 287 PKGTPGVAGPSGEPG---MPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAG 343
            KG  G  G +GE G    PG  G+NG+PG +G  G  G  GAPGE+G    PGLPG AG
Sbjct: 262 MKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGR---PGLPGAAG 318

Query: 344 SKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA------------LG 391
           ++G  G RG  G+ G  GP G  G PG  G  GE G AG  GS GA             G
Sbjct: 319 ARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG 378

Query: 392 PQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGA----------------- 434
            QGPPG PG+ G  G KG MG  G+PG  GL G  G  GP GA                 
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG 438

Query: 435 ----AGPKGDQGIAGSDGLPGDKGELGPS------------GLVGPKGESGSRGELGPKG 478
                GP+G++G AG  G+PG KGE G              G  G +G  G RG  GP G
Sbjct: 439 AKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498

Query: 479 TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538
             G  G +G +G PGP GP G  G PG  G+ G PG+ G   S        GG  S+   
Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSP-------GGPGSD--- 548

Query: 539 QLAAHLRKPLAPGS---IGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPR 595
                  KP  PGS    GRPGP GP GP G PG +G PG +G  G  G  GE G PG  
Sbjct: 549 ------GKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGP 602

Query: 596 GNQGDRGDKGAAG----AGLDGPEGDQ------GPQGPQGVPGT-SKDGQDGAPGEPGPP 644
           G QG  G  G  G     G  GP GD+      GPQG QG+PGT    G++G PGEPGP 
Sbjct: 603 GPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662

Query: 645 GDPGLPGAIGAQGTPG 660
           GD G PGA G +G  G
Sbjct: 663 GDAGAPGAPGGKGDAG 678



 Score =  323 bits (827), Expect = 4e-88
 Identities = 200/486 (41%), Positives = 233/486 (47%), Gaps = 56/486 (11%)

Query: 207 DGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGP---PGDRGPIGFRGPPGIPGAPGK 263
           D E   P P  P G   +V  Q P      P   GP    GD GP G  G  G PG PG+
Sbjct: 69  DQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQ 128

Query: 264 AGDRGERGPEGF-----RGP------------KGDLGRPGPKGTPGVAGPSGEPGMPGKD 306
            G  G  GP G       GP            K  +   G  G PG AGP G PG PG  
Sbjct: 129 PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS 188

Query: 307 GQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEP 366
           G  G PG  G +G  G  G  G  GP G PG  G +G  G+ GE GR G  GE G  G P
Sbjct: 189 GHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPP 248

Query: 367 GVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDV 426
           G+ G AG+PG  G  GHRG  G  G +G  GAPG++G  G  G  G PG  GP+G  G+ 
Sbjct: 249 GIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGER 308

Query: 427 GDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTS 486
           G  G  GAAG +G+ G  GSDG PG     GP G  G  G  G++GE+GP G+ G NG  
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQPGPP---GPPGTAGFPGSPGAKGEVGPAGSPGSNGAP 365

Query: 487 GVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRK 546
           G +G PGP G  G QG PG PGI G PG  G+                            
Sbjct: 366 GQRGEPGPQGHAGAQGPPGPPGINGSPGGKGE---------------------------- 397

Query: 547 PLAPGSI-GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKG 605
            + P  I G PG  G  GPPGP G+ G PG RG  G  G  G  G+PGPRG +G+ G  G
Sbjct: 398 -MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPG 456

Query: 606 AAGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDT 664
             GA G DG +G  G  G  G+PG +  G+ GAPG  GP G  G+PG  G  G  G    
Sbjct: 457 VPGAKGEDGKDGSPGEPGANGLPGAA--GERGAPGFRGPAGPNGIPGEKGPAGERGAPGP 514

Query: 665 SACQGA 670
           +  +GA
Sbjct: 515 AGPRGA 520



 Score =  301 bits (772), Expect = 1e-81
 Identities = 175/385 (45%), Positives = 188/385 (48%), Gaps = 6/385 (1%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            G+ GPPG  GP G PG  G+ GE G PG PG  G  GA G PG PG  G PG PG  G  
Sbjct: 840  GVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSP 899

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGGK-GLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147
            G+DGPPGP G  G  GS G  GP G  G+ G  G PG  G  G PG +G+ G  G  GL 
Sbjct: 900  GKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLA 959

Query: 148  GLPGPPGPPGPPGHPGVLPE----GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGE 203
            G PG PGP G PG  GV  E    GA  L      PPGP G PG+ G  G  G  G  G 
Sbjct: 960  GPPGMPGPRGSPGPQGVKGESGKPGANGLSGER-GPPGPQGLPGLAGTAGEPGRDGNPGS 1018

Query: 204  VGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGK 263
             G  G  G PG  G  G  GS G  G  G  G PGP+GP G  G  G  GP G  GAPG 
Sbjct: 1019 DGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGP 1078

Query: 264  AGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGR 323
            AG RG  GP+G RG KG+ G  G  G  G  G  G PG PG  G  G  G  G  G AG 
Sbjct: 1079 AGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP 1138

Query: 324  NGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH 383
             G  G  GP G  G  G  G  G  G RG  GE G  G  G PG PG  G PG  G    
Sbjct: 1139 RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198

Query: 384  RGSAGALGPQGPPGAPGVRGFQGQK 408
               A A+   G   A G   + G +
Sbjct: 1199 GVGAAAIAGIGGEKAGGFAPYYGDE 1223



 Score =  291 bits (746), Expect = 1e-78
 Identities = 173/388 (44%), Positives = 193/388 (49%), Gaps = 42/388 (10%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKP--- 73
            GE  +  G    G PG  G PGPPG  G  G  G +G PG  GPPGP G  G PG P   
Sbjct: 861  GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS 920

Query: 74   ---GEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVS 129
               G+AG PG  G  G  G  G PGP G  G  G+ G  GPPG+ G +G PGP G  G S
Sbjct: 921  GPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGES 980

Query: 130  GPPGGIGL---RGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPP 186
            G PG  GL   RGPPGP GLPGL G  G PG  G+                     PG  
Sbjct: 981  GKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGN---------------------PGSD 1019

Query: 187  GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDR 246
            G+PG  G  G KG++GE G  G  G PG PGP   PG VG  G  G RG  GP GP G  
Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP---PGPVGPAGKSGDRGESGPAGPAGAP 1076

Query: 247  GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKD 306
            GP G RG PG  G  G  G+ GERG  G +G +G  G PG  G+PG AG  G  G PG  
Sbjct: 1077 GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPA 1136

Query: 307  GQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEP 366
            G  G  G  G  G+ G +G PG  GP      PG  G++GE+G  G  G  G+ GP G P
Sbjct: 1137 GPRGPVGPSGPPGKDGTSGHPGPIGP------PGPRGNRGERGSEGSPGHPGQPGPPGPP 1190

Query: 367  GVPGD-AGMPGERGEAGHRG-SAGALGP 392
            G PG   G  G    AG  G  AG   P
Sbjct: 1191 GAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218



 Score =  146 bits (369), Expect = 5e-35
 Identities = 96/237 (40%), Positives = 116/237 (48%), Gaps = 35/237 (14%)

Query: 479 TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538
           T+ PNG  G QG  G PGP G+ G  G PGI G+PG PG       I E C         
Sbjct: 96  TRPPNG-QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPG-SPGPPGICESCPTGPQNYSP 153

Query: 539 QLAAH-LRKPLAPGSI-GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRG 596
           Q  ++ ++  +A G + G PGPAGPPGPPGPPG+ GHPG+ G PGY+GP GE G  GP G
Sbjct: 154 QYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSG 213

Query: 597 NQGDRGDKGAAG----------------AGLDGPEGDQGPQGPQGVPG----------TS 630
             G  G  G +G                 GL GP G +GP G  G PG            
Sbjct: 214 PPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNG 273

Query: 631 KDGQDGAP---GEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSRSS 684
           + G+ GAP   GE G PG+ G PG +G +G PG        GA   G     G+R S
Sbjct: 274 EKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGA--AGARGNDGARGS 328


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  527 bits (1357), Expect = e-149
 Identities = 316/729 (43%), Positives = 362/729 (49%), Gaps = 120/729 (16%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPG------LPGPPGPKGAPGKPGKPGEAGLPGL- 81
            GLPGPPG  G PG  G  G DG AGP G       PGP GPKG+PG+ G+PGEAGLPG  
Sbjct: 479  GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK 538

Query: 82   --------PGVDGLTG---------RDGPPGPKGAPGERGSLGPPGPPGLGG-------K 117
                    PG DG TG         R GPPGP GA G+ G +G PGP G  G       +
Sbjct: 539  GLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGER 598

Query: 118  GLPGPPGEAGVSGPPGGIGLRGPPGPSG---------------LPGLPGPPGPPGPPGHP 162
            G+PGPPG  G +G  G  G +GPPGP+G                 GLPGP GPPG  G P
Sbjct: 599  GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658

Query: 163  GVLPEGAT-DLQCPSICPPGPPGPPGMPGFKG------PTGYKGEQGEVGKDGEKGD--- 212
            G   +G   DL  P   P G  G  G PG +G      P G +G  G  G DG KGD   
Sbjct: 659  G--EQGVPGDLGAPG--PSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714

Query: 213  PGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIG------------FRGPPGIPGA 260
            PG PG  G PG  G+ G RG  GLPGP G  GD GP G              GP G PG 
Sbjct: 715  PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774

Query: 261  PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGE 320
             G  GD+GE GP G  GP G  G PG +G PG  GP+G  G PG DGQ G  G  G  G 
Sbjct: 775  AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGA 834

Query: 321  AGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGE 380
             G  G PG  GP G PG  G  G+ G KG RG AG     G +G PG  G  G PG  G 
Sbjct: 835  KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP---PGATGFPGAAGRVGPPGPSGN 891

Query: 381  AGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGD 440
            AG  G  G  G +G  G  G  G  G+ G +G PG PGP G +G  G  GP GA G  G 
Sbjct: 892  AGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGP 951

Query: 441  QGIAGSDG---LPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGP 497
            QGIAG  G   LPG +GE G  GL GP GE G +G  G  G +GP G  G  G+ GPPG 
Sbjct: 952  QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE 1011

Query: 498  LGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPG 557
             G +G PG  G  G+ G PG +                           P APG+ G PG
Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGE----------------TGPAGPPGAPGAPGAPG 1055

Query: 558  PAGPPG---------PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG 608
            P GP G         P GP G +G  GARGP G +GP G+ G+ G +G++G +G +G +G
Sbjct: 1056 PVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSG 1115

Query: 609  A----------GLDGPEGDQGPQGPQGVPGTS----KDGQDGAP---GEPGPPGDPGLPG 651
                       G  GP G  GP GP+G PG++    KDG +G P   G PGP G  G  G
Sbjct: 1116 LQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAG 1175

Query: 652  AIGAQGTPG 660
             +G  G PG
Sbjct: 1176 PVGPPGPPG 1184



 Score =  524 bits (1350), Expect = e-148
 Identities = 314/700 (44%), Positives = 348/700 (49%), Gaps = 98/700 (14%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP------PGP---------KGAPGKPGKP 73
           G  GP GP G PG PG++G  G+ GP GLPG       PGP          GA G PG  
Sbjct: 278 GDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT 337

Query: 74  GEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPG 133
           G AG PG PG  G  G  GP GP+G+ G +G  G PGPPG  G    GP G  G  G PG
Sbjct: 338 GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAA--GPAGNPGADGQPG 395

Query: 134 GIGLRGPPGPSGLPGLP------GPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPG 187
             G  G PG +G PG P      GP GP GPPG  G   E             G PGP G
Sbjct: 396 AKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG 455

Query: 188 MPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS---------VGLQGPRGLRGLPG 238
           + G  GP G +G++G  G+ G  G PGPPG  G PGS          G +GP G RG PG
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG 515

Query: 239 PLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDL---GRPGPKGTPGV-- 293
           P GP G  G  G  G  G+PGA G  G  G  GP+G  GP G     GRPGP G PG   
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG 575

Query: 294 -------AGPSGEPGMPGKDGQNGVPGLD------GQKGEAGRNGAPGEKGPNGLPGLPG 340
                   GP G  G PGK G+ GVPG        G+ GEAG  G PG  GP G  G  G
Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG 635

Query: 341 RAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMP------GERGEAGHRGSAGALGPQG 394
            AGS G +G  G AG  GEAG  GE GVPGD G P      GERG  G RG  G  GP G
Sbjct: 636 PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695

Query: 395 PPGAPGVRGFQGQKGSMGDPGLPGPQ---GLRGDVGDRGPGGAAGPKGDQGIA---GSDG 448
           P GA G  G  G KG  G PG PG Q   GL+G  G+RG  G  GPKGD+G A   G+DG
Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADG 755

Query: 449 LPGD---KGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGV---QGVPGPPGPLGLQG 502
            PG    +G  GP G  GP G  G +GE GP G  GP G  G    +G PGPPGP G  G
Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815

Query: 503 VPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPP 562
            PG  G  G  G PG                               A G  G PGPAGP 
Sbjct: 816 PPGADGQPGAKGEPGDAG----------------------------AKGDAGPPGPAGPA 847

Query: 563 GPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQ 621
           GPPGP G++G PGA+G  G  GP G  G PG  G  G  G  G AG  G  GP G +G +
Sbjct: 848 GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK 907

Query: 622 GPQGVPG-TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
           GP+G  G   + G+ G PG PGP G+ G PGA G  G PG
Sbjct: 908 GPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPG 947



 Score =  516 bits (1330), Expect = e-146
 Identities = 322/730 (44%), Positives = 361/730 (49%), Gaps = 98/730 (13%)

Query: 29   GLPGPPGP------PGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPG---KPGEAGLP 79
            G  GPPGP      PG PG  G  G  GE GP G+ GPPGP G  GK G   +PG  GLP
Sbjct: 422  GPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLP 481

Query: 80   GLPGVDG------LTGRDGPPGPKGAPGERGSLGPPGPPGLGGK-------GLPGPPGEA 126
            G PG  G        G DG  GPKG  GERGS GP GP G  G+       GLPG  G  
Sbjct: 482  GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541

Query: 127  GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPP 186
            G  G PG  G  GPPGP+G  G PGPPGPPG  G  GV+             P G  G P
Sbjct: 542  GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG---------PKGAAGEP 592

Query: 187  GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRG---LRGLPGPLGPP 243
            G  G +G  G  G  G  GKDGE G  GPPGPAG  G  G QGP G    +GLPGP GPP
Sbjct: 593  GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP 652

Query: 244  GDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT---PGVAGPSGEP 300
            G+ G  G +G PG  GAPG +G RGERG  G RG +G  G  GP+G    PG  G  G+ 
Sbjct: 653  GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712

Query: 301  GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA 360
            G PG  G  G PGL G  GE G  G PG KG  G  G  G  GS G+ G RG  G +G  
Sbjct: 713  GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772

Query: 361  GPSGEPGVPGDAG------------MPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQK 408
            GP+G PG  G++G             PG+RGE G  G AG  GP G  G PG +G  G  
Sbjct: 773  GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA 832

Query: 409  GSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAG---SDGLPGDKGELGP------S 459
            G+ GD G PGP G  G  G  G  GA G KG +G AG   + G PG  G +GP      +
Sbjct: 833  GAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNA 892

Query: 460  GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE 519
            G  GP G +G  G  GP+G  GP G  G  G PGPPGP G +G PG  G  G PG PG +
Sbjct: 893  GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQ 952

Query: 520  --ASEQRIRELCGGMISEQIAQLAAHLRKPL------APGSIGRPGPAGPPGPPGPPGSI 571
              A ++ +  L G         L     +P       A G  G PGP GPPG  GPPG  
Sbjct: 953  GIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGES 1012

Query: 572  GH---PGARGPPGY---------RGPTGELGDPG------------PRGNQGDRGDKGAA 607
            G    PGA G PG          RG TG  G PG            P G  GDRG+ G A
Sbjct: 1013 GREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA 1072

Query: 608  G-AGLDGPEGDQGPQGPQGVPG----TSKDGQDGAPGE---PGPPGDPGLPGAIGAQGTP 659
            G AG  GP G +GP GPQG  G    T + G  G  G     G  G PG PG+ G QG  
Sbjct: 1073 GPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS 1132

Query: 660  GICDTSACQG 669
            G    +  +G
Sbjct: 1133 GASGPAGPRG 1142



 Score =  515 bits (1326), Expect = e-146
 Identities = 325/769 (42%), Positives = 369/769 (47%), Gaps = 137/769 (17%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGE------------AGPPGLPG---PPGPKGAPGKPGKP 73
            G PGPPGP G  G  G  G DG+            AG PG PG   P GP+G  G PG  
Sbjct: 371  GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPK 430

Query: 74   GEAGLPGLPGVDGLTGR---------DGPPGPKGAPGERGSLGPPGPPGL-------GGK 117
            G +G PG PG  G TG           GPPGP G  G+RG+ G PGP GL       GG 
Sbjct: 431  GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP 490

Query: 118  GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL----------PE 167
            G  G PG  GV+GP G  G RG PGP+G  G PG  G PG  G PG            P+
Sbjct: 491  GSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPD 550

Query: 168  GATDLQCPS--ICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSV 225
            G T    P+     PGPPGPPG  G  G  G+ G +G  G+ G+ G+ G PGP G  G  
Sbjct: 551  GKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPA 610

Query: 226  GLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRP 285
            G  G  G +G PGP GP G+RG  G  G PG  G PG AG  GE G  G +G  GDLG P
Sbjct: 611  GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAP 670

Query: 286  GP------KGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLP 339
            GP      +G PG  G  G PG  G  G NG PG DG KG+AG  GAPG +G  GL G+P
Sbjct: 671  GPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMP 730

Query: 340  GR---AGSKGEKGERGRAGELGEAGPSGEPGV---------PGDAGMPGERGE------A 381
            G    AG  G KG+RG AG  G  G  G+ GV         PG AG PG++GE      A
Sbjct: 731  GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790

Query: 382  GHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL---PGPQGLRGDVGDRGPGGAAGP- 437
            G  G+ GA G +G PG PG  GF G  G+ G PG    PG  G +GD G  GP G AGP 
Sbjct: 791  GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850

Query: 438  --------------KGDQGIAGSDGLPGDKGELGP------SGLVGPKGESGSRGELGPK 477
                          +G  G  G+ G PG  G +GP      +G  GP G +G  G  GP+
Sbjct: 851  GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPR 910

Query: 478  GTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE--ASEQRIRELCGGMISE 535
            G  GP G  G  G PGPPGP G +G PG  G  G PG PG +  A ++ +  L G     
Sbjct: 911  GETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGER 970

Query: 536  QIAQLAAHLRKP------LAPGSIGRPGPAGPPGPPGPPGSIGH---PGARGPPGY---- 582
                L     +P       A G  G PGP GPPG  GPPG  G    PGA G PG     
Sbjct: 971  GFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSP 1030

Query: 583  -----RGPTGELGDP------------GPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQ 624
                 RG TG  G P            GP G  GDRG+ G AG AG  GP G +GP GPQ
Sbjct: 1031 GAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQ 1090

Query: 625  GVPGTSKD-------------GQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            G  G   +             G  G  G PGPPG PG  G  GA G  G
Sbjct: 1091 GPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAG 1139



 Score =  512 bits (1319), Expect = e-145
 Identities = 316/769 (41%), Positives = 358/769 (46%), Gaps = 118/769 (15%)

Query: 29  GLPGPPGPPGPPGKPGQDG-------------------IDGEAGPPGLPGPPGPKGAPGK 69
           GLPGPPGPPGPPG PG  G                   + G  GP G  G PGP GAPG 
Sbjct: 139 GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGP 198

Query: 70  PGKPGEAGLPGLPGVDGLTGRDGPPGPKGA---------PGERGSLGPPGPPGLGG---- 116
            G  G  G PG PG  G  G  GPPGP G          PG  G  GPPGP G  G    
Sbjct: 199 QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGT 258

Query: 117 KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGP------------PGHPGV 164
            GLPG  G  G SG  G  G  GP GP G PG PG  G PG             PG PG 
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318

Query: 165 LPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGE------QGEVGKDGEKGDPGPPGP 218
                 D    +  PPGP GP G PGF G  G KGE      +G  G  G +G+PGPPGP
Sbjct: 319 AGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378

Query: 219 AGL------------PGSVGLQGPRGLRGLP---------GPLGPPGDRGPIGFRGPPGI 257
           AG             PG+ G  G  G+ G P         GP GP G  GP G  G PG 
Sbjct: 379 AGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGA 438

Query: 258 PGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGK---DGQNGVPGL 314
           PG+ G  G +GE GP G +GP G  G  G +G  G  GP+G PG PG+    G  G PG 
Sbjct: 439 PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA 498

Query: 315 D---GQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGD 371
           D   G KG AG  G+PG  GP G PG  GR G  G  G +G  G  G  GP G+ G PG 
Sbjct: 499 DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558

Query: 372 A---------------------GMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGS 410
           A                     G PG +G AG  G AG  G  GPPGA G  G  G+ G+
Sbjct: 559 AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA 618

Query: 411 MGDPGLPGPQGLRGDVGDRG-PG-----GAAGPKGDQGIAGSDGLPGDKGELGPSGLVGP 464
            G PG  GP G RG+ G  G PG     G AGP G+ G  G  G+PGD G  GPSG  G 
Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678

Query: 465 KGESGSRGELGPKGTQGPNGTSGV---------QGVPGPPGPLGLQGVPGVPGITGKPGV 515
           +G  G RG  GP G  GP G +G           G PG PG  G  G+ G+PG  G  G+
Sbjct: 679 RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738

Query: 516 PGK--EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGH 573
           PG   +  +   +   G    + +  L   +  P   G+ G  G +GP GP GP G+ G 
Sbjct: 739 PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA 798

Query: 574 PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQG-VPGTSK 631
           PG RG PG  GP G  G PG  G  G +G+ G AGA G  GP G  GP GP G +     
Sbjct: 799 PGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGA 858

Query: 632 DGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSG 680
            G  GA G  GPPG  G PGA G  G PG    +   G   G  G++ G
Sbjct: 859 PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP-GPAGKEGG 906



 Score =  511 bits (1315), Expect = e-144
 Identities = 313/695 (45%), Positives = 352/695 (50%), Gaps = 61/695 (8%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAG--LPGLP-GVD 85
           G  GP GP GP G PG+DGI G+   PGLPGPPGP   PG PG PG  G   P L  G D
Sbjct: 115 GDTGPRGPRGPAGPPGRDGIPGQ---PGLPGPPGP---PGPPGPPGLGGNFAPQLSYGYD 168

Query: 86  -GLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEAGVSGPPGGIGLRGPPGP 143
              TG    PGP G  G RG  GPPG PG  G +G PG PGE G SGP G  G  GPPG 
Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228

Query: 144 SGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGE 203
           +G  G  G PG PG  G PG  P+GA  L       PG  G PGM G +G +G  G +G+
Sbjct: 229 NGDDGEAGKPGRPGERGPPG--PQGARGL-------PGTAGLPGMKGHRGFSGLDGAKGD 279

Query: 204 VGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDR------------GPIGF 251
            G  G KG+PG PG  G PG +G +G  G RG PG  GP G R            GP G 
Sbjct: 280 AGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGP 339

Query: 252 RGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP---GMPGKDGQ 308
            GPPG PGA G  G+ G +GP G  GP+G  G PGP G  G AGP+G P   G PG  G 
Sbjct: 340 AGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGA 399

Query: 309 NGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGV 368
           NG PG+ G  G  G  G  G +GP G PG  G +G  G  G +G  G  GE GP G  G 
Sbjct: 400 NGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGP 459

Query: 369 PGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGD 428
           PG AG  G+RG  G  G  G  GP G  G PG RGF G  G  G  G  G +G  G  G 
Sbjct: 460 PGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGP 519

Query: 429 RGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGV 488
           +G  G AG  G+ G+ G+ GL G  G  GP G  GP G +G  G  GP G  G  G +GV
Sbjct: 520 KGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGV 579

Query: 489 QGVPGP------PGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAA 542
            G PGP      PG  G +GVPG PG  G  G  G+  ++        G   E+  Q  A
Sbjct: 580 MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP--AGPAGERGEQGPA 637

Query: 543 HLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRG 602
                 +PG  G PGPAGPPG  G PG  G PG  G PG  G  GE G PG RG QG  G
Sbjct: 638 G-----SPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPG 692

Query: 603 DKGAAGA----GLDGPEGD---QGPQGPQGVPG-TSKDGQDGAPGEPGPPGDPGLPGAIG 654
             G  GA    G DG +GD    G  G QG PG     G+ GA G PGP GD G  G  G
Sbjct: 693 PAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKG 752

Query: 655 AQGTPGICDTSACQGAV-----LGGVGEKSGSRSS 684
           A G+PG        G +      G  G+K  S  S
Sbjct: 753 ADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPS 787



 Score =  504 bits (1299), Expect = e-143
 Identities = 303/693 (43%), Positives = 343/693 (49%), Gaps = 94/693 (13%)

Query: 25   AQRVGLPGPPGPPGPPGKPGQDGIDGEAGPP------GLPGP---------------PGP 63
            A R G  G PG  G  G PG  G DG+ GPP      G PGP               PGP
Sbjct: 526  AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP 585

Query: 64   KGAPGKPGKPGEAGLPGLPGV------DGLTGRDGPPGPKGAPGERGSLGPPGPPGLGG- 116
            KGA G+PGK GE G+PG PG       DG  G  GPPGP G  GERG  GP G PG  G 
Sbjct: 586  KGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGL 645

Query: 117  KGLPGPPGEAGVSGPPGGIGLRGPPGPS------GLPGLPGPPGPPGPPGHPGVLPEGAT 170
             G  GPPGEAG  G  G  G  G PGPS      G PG  G  GPPGP G  G       
Sbjct: 646  PGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705

Query: 171  DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP 230
            D        PG PG  G PG +G  G +G  G  G  G++GD GP G  G PG  G++G 
Sbjct: 706  DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGL 765

Query: 231  RGLRGLPGPLGPPGDR---GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP 287
             G  G PGP G PGD+   GP G  GP G  GAPG  G+ G  GP GF GP G  G+PG 
Sbjct: 766  TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825

Query: 288  KGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE 347
            KG PG AG  G+ G PG  G  G PG  G  G  G  GA G  GP G  G PG AG  G 
Sbjct: 826  KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 885

Query: 348  KGERGRAGELGEAGPSGE------------PGVPGDAGMPGERGEAGHRGSAGALGPQGP 395
             G  G AG  G  GP+G+             G PG+ G PG  G AG +GS GA GP G 
Sbjct: 886  PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGA 945

Query: 396  PGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE 455
            PG PG +G  GQ+G +   GLPG +G RG  G  GP G  G +G  G +G  G P   G 
Sbjct: 946  PGTPGPQGIAGQRGVV---GLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPP---GP 999

Query: 456  LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGV 515
            +GP GL GP GESG  G  G +G+ G +G+ G +G  G  GP G  G PG PG  G  G 
Sbjct: 1000 MGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGP 1059

Query: 516  PGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPG 575
             GK                                G  G  GPAGP GP GP G+ G  G
Sbjct: 1060 AGKS-------------------------------GDRGETGPAGPAGPVGPVGARGPAG 1088

Query: 576  ARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG----AGLDGPEGDQGPQGPQGVPGTS- 630
             +GP G +G TGE GD G +G++G  G +G  G     G  GP G  GP GP+G PG++ 
Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG 1148

Query: 631  ---KDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
               KDG +G PG  GPPG  G  G  G  G PG
Sbjct: 1149 APGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPG 1181



 Score =  450 bits (1158), Expect = e-126
 Identities = 258/585 (44%), Positives = 294/585 (50%), Gaps = 77/585 (13%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            GLPGP GPPG  GKPG+ G+ G+ G PG  G  G +G PG+ G  G  G  G  G +G  
Sbjct: 644  GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGGK----GLPGPPGEAGVSGPPGGIGLRGPPGPS 144
            G DG  G  GAPG  GS G PG  G+ G+    GLPGP G+ G +GP G     G PG  
Sbjct: 704  GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA---DGSPGKD 760

Query: 145  GLPGLPGPPGPPGPPGHPGVL----PEGATDLQCPSICP-----PGPPGPPGM---PGFK 192
            G+ GL GP GPPGP G PG      P G          P     PGPPGP G    PG  
Sbjct: 761  GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGAD 820

Query: 193  GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVG------LQGPRGLRGLPGPLGPPGDR 246
            G  G KGE G+ G  G+ G PGP GPAG PG +G       +G RG  G PG  G PG  
Sbjct: 821  GQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880

Query: 247  GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKD 306
            G +G  GP G  G PG  G  G+ G +G RG  G  GRPG  G PG  GP+GE G PG D
Sbjct: 881  GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940

Query: 307  GQNGVPGLDGQKGEAGRNGA---PGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPS 363
            G  G PG  G +G AG+ G    PG++G  G PGLPG +G  G++G  G +GE G  GP 
Sbjct: 941  GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 364  GEPGV------------PGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGF------Q 405
            G PG+            PG  G PG  G  G +G  G  GP GPPGAPG  G        
Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPA 1060

Query: 406  GQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPK 465
            G+ G  G+ G  GP G  G VG RGP G  GP+GD+G  G  G  G KG  G SGL GP 
Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPP 1120

Query: 466  GESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRI 525
            G  GS GE GP G  GP G  G  G  G PG  GL G+PG  G  G  G  G        
Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD------- 1173

Query: 526  RELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGS 570
                                     G +G PGP GPPGPPGPP +
Sbjct: 1174 ------------------------AGPVGPPGPPGPPGPPGPPSA 1194



 Score =  439 bits (1130), Expect = e-123
 Identities = 266/618 (43%), Positives = 303/618 (49%), Gaps = 76/618 (12%)

Query: 94  PGPKGAPGERGSLGPPG---PPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLP 150
           PG +   GE   + P G   P      G+ GP G+ G  GP G  G  G  G  G PGLP
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 151 GPPGPPGPPGHPGV-------LPEGATDLQCPSICPPGPPGP------PGMPGFKGPTGY 197
           GPPGPPGPPG PG+       L  G  +     I  PGP GP      PG PG  GP G+
Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201

Query: 198 KGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGI 257
           +G  GE G+ G  G  GP GP G PG  G  G  G  G PG  GPP   GP G RG PG 
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPP---GPQGARGLPGT 258

Query: 258 PGAPGKAGDRGERGPEGFR------GPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
            G PG  G RG  G +G +      GPKG+ G PG  G PG  GP G PG  G+ G  G 
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318

Query: 312 PGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGD 371
            G  G  G  G  G PG  GP G PG PG  G+KGE G +G  G  G  G  GEPG PG 
Sbjct: 319 AGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378

Query: 372 AGM------PGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDP------GLPGP 419
           AG       PG  G+ G +G+ GA G  G PG PG RG  G +G  G P      G PG 
Sbjct: 379 AGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGA 438

Query: 420 QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE---SGSRGELGP 476
            G +GD G +G  G  G +G  G AG +G  G +GE GP+GL GP GE    GSRG  G 
Sbjct: 439 PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA 498

Query: 477 KGTQGPNGTSGVQGVPGPPGPLGL---------QGVPGVPGITGKPGVPGKEASEQRIRE 527
            G  GP G +G +G PGP GP G           G+PG  G+TG PG PG +        
Sbjct: 499 DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK------ 552

Query: 528 LCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTG 587
                              P   G  GRPGP GPPG  G  G +G PG +G  G  G  G
Sbjct: 553 ----------------TGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596

Query: 588 ELGDPGPRGNQGDRGDKGAAGA----GLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPG 642
           E G PGP G  G  G  G AGA    G  GP G++G QGP G PG     G  G PGE G
Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656

Query: 643 PPGDPGLPGAIGAQGTPG 660
            PG+ G+PG +GA G  G
Sbjct: 657 KPGEQGVPGDLGAPGPSG 674



 Score =  298 bits (762), Expect = 1e-80
 Identities = 173/371 (46%), Positives = 193/371 (52%), Gaps = 20/371 (5%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGP---PGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKP 73
            G+  A   A   G  GP GPPGP    G PG  G  G AGPPG  G PG  G  G PG  
Sbjct: 830  GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889

Query: 74   GEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEAGVSGPP 132
            G AG PG PG  G  G  GP G  G  G  G +GPPGPPG  G KG PG  G AG  G P
Sbjct: 890  GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949

Query: 133  GGIGLRGPPGPSGLP------GLPGPPGPPGPPGHPGVLPEGATDLQCP--SICPPGPPG 184
            G  G+ G  G  GLP      G PG PGP G PG  G  P GA+  + P   + PPG  G
Sbjct: 950  GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQG--PSGASGERGPPGPMGPPGLAG 1007

Query: 185  PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG 244
            PPG  G +G  G +G  G  G  G KGD G  GPAG PG+ G  G  G  G  G  G  G
Sbjct: 1008 PPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRG 1067

Query: 245  DRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPG 304
            + GP G  GP G  GA G AG +G RG +G  G +GD G  G +G  G+ GP G PG PG
Sbjct: 1068 ETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPG 1127

Query: 305  KDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSG 364
            + G +G  G  G +G  G  GAPG+ G NGLP      G  G  G RGR G+ G  GP G
Sbjct: 1128 EQGPSGASGPAGPRGPPGSAGAPGKDGLNGLP------GPIGPPGPRGRTGDAGPVGPPG 1181

Query: 365  EPGVPGDAGMP 375
             PG PG  G P
Sbjct: 1182 PPGPPGPPGPP 1192


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  526 bits (1355), Expect = e-149
 Identities = 309/704 (43%), Positives = 372/704 (52%), Gaps = 80/704 (11%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDG-- 86
            G PGP G PG PG  G++G +G  GP GL GP GP G  GK G+PG  G  GLPG  G  
Sbjct: 488  GRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPK 547

Query: 87   ----LTGRDGPPGPKGAPGERGSLGPPGPPG----LGGKGLPGPPGEAGVSGPPGGIGLR 138
                  G  G PG KG  G+ G +G PGPPG     G +G PGP G+AG  GP G +G R
Sbjct: 548  GDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPR 607

Query: 139  GPPGPSGLPGLP------------GPPGPPGPPGHPGVLPEGATDLQCPSIC-------- 178
            G PGP+G PG+             GPPG PGPPG  G    G+  L  P           
Sbjct: 608  GSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG--NHGSQGLPGPQGLIGTPGEKG 665

Query: 179  PPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPG 238
            PPG PG PG+PG  GP G+ G +G  G+ G +G PG  GP G PG  G++G  G RGL G
Sbjct: 666  PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQG 725

Query: 239  PLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSG 298
              G  G+ G  GF+G  G+ G  GK G  G RG +G  GPKG  G+ G +G PG AG  G
Sbjct: 726  EKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKG 785

Query: 299  EPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPN---GLPGLPGRAGSKGEKGERGRAG 355
            + G+PG  G  G PG  G  G  G  G  GEKG +   G PGL G  G  G +GERG+ G
Sbjct: 786  KLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPG 845

Query: 356  ELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP---------PGAPGVR---G 403
              G+ GP G+ G  G  G+PGE+G  G +G  G  GP+GP         PG PG R   G
Sbjct: 846  ATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELG 905

Query: 404  FQGQKGSMGDPGLPGPQGLRGDV---GDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG 460
            FQGQ G  G  G+ GPQG  G+V   G+RGP G  GP G+QG+ G +G  G KGELGP G
Sbjct: 906  FQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPG 965

Query: 461  LVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKP---GVPG 517
             +G +G +G RG  GPKG  G  G +G++G  GPPGP+G  G PG  G  G     G+PG
Sbjct: 966  PLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPG 1025

Query: 518  KEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGAR 577
            +  SE  +                    K  + G  G PGP G  G PGP G +G PGA 
Sbjct: 1026 QSGSEGPV----------------GPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAA 1069

Query: 578  GPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-------AGLDGPEGDQGPQGPQGVPG-- 628
            GP G  G  G++G PG +G++GD+GD G  G       AG  GP G  G QG +G PG  
Sbjct: 1070 GPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLF 1129

Query: 629  --TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGA 670
                 DG  G  G  GPPG  GLPG  G +G  G   +    GA
Sbjct: 1130 GQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGA 1173



 Score =  521 bits (1342), Expect = e-148
 Identities = 317/704 (45%), Positives = 365/704 (51%), Gaps = 92/704 (13%)

Query: 28   VGLPGPPGP---PGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAG---LPGL 81
            +G PGP GP    G  GK GQ G++GE GPPG  G  G  GA G+PG  G+ G    PG+
Sbjct: 805  IGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGI 864

Query: 82   PGVDGLTGRDGPPG---PKGAPGERGSLGPPGPPG----LGGKGLPGPPGEAGVSGPPGG 134
            PG  GL G  GPPG   PKG PG +G  G PG PG    LG +G  GPPG AGV GP G 
Sbjct: 865  PGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGK 924

Query: 135  IGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGP------------ 182
             G  GP G  G PG PGPPG  G PG  G   EGA       + PPGP            
Sbjct: 925  TGEVGPLGERGPPGPPGPPGEQGLPGLEG--REGAKG----ELGPPGPLGKEGPAGLRGF 978

Query: 183  PGPPGMPGFKGPTGYKGEQGE---VGKDGEKGDPGPPGPAG---LPGSVGLQGP------ 230
            PGP G PG  GPTG KG++G    VG +G  G+ GP GPAG   LPG  G +GP      
Sbjct: 979  PGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGK 1038

Query: 231  ---RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP 287
               RG RG PGP G  G  GP+G  GPPG  G  G+ GD+G+ G  G +G KGD G  GP
Sbjct: 1039 KGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGP 1098

Query: 288  KGTPGVAGPSGEPGMPGKDG---QNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGS 344
             G PG+ GP+G PG PG DG   + G PGL GQKG+ G  G  G  GP GL GLPG  G 
Sbjct: 1099 PGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGE 1158

Query: 345  KGEKGERGRAGELGEAGP---------SGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP 395
            KGE G+ G  G  G  GP          G PG+PG  G PG  GE G RG AG  GP G 
Sbjct: 1159 KGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGA 1218

Query: 396  PGAPGVRGFQGQKGSMGDPGLPGP---------QGLRGDVGDRGPGGAAGPKGDQGIAGS 446
            PG PG +G  G+KG  G  G  GP          G +G VG  G  G  GP GD G++G 
Sbjct: 1219 PGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGI 1278

Query: 447  DGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGV 506
            DG PG+KG+ G  G  GP G SG  G  GP G +GP+G  G +G  G  G  G  G  G 
Sbjct: 1279 DGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGP 1338

Query: 507  PGITGKPGVPGK--EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGP 564
            PG TG  G  G       + +R +  G + E              PG +G PG  GPPGP
Sbjct: 1339 PGRTGPMGARGPPGRVGPEGLRGI-PGPVGE--------------PGLLGAPGQMGPPGP 1383

Query: 565  PGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGP 623
             GP G  G  G  GP G +G  G +G  GP G  G++GD+G  G  G  GP+GD GP GP
Sbjct: 1384 LGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGP 1443

Query: 624  ------QGVPGTSKD-GQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
                   G PG +   GQ G+ G PG  G  G  G  G  G PG
Sbjct: 1444 IGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487



 Score =  518 bits (1335), Expect = e-147
 Identities = 325/751 (43%), Positives = 374/751 (49%), Gaps = 139/751 (18%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKP------------------------GQDGIDGEA 52
            GE      A   G  G PG PG PG+P                        GQ G++GE 
Sbjct: 773  GEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGER 832

Query: 53   GPPGLPGPPGPKGAPGKPGKPGEA---GLPGLPGVDGLTGRDGP---PGPKGAPGERGSL 106
            GPPG  G  G  GA G+PG  G+    G PG+PG  GL G  GP   PGPKG PG +G  
Sbjct: 833  GPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKD 892

Query: 107  GPPGPPG----LGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHP 162
            G PG PG    LG +G  GPPG AGV GP G  G  GP G  G PG PGPPG  G PG  
Sbjct: 893  GRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLE 952

Query: 163  GVLPEGATDLQCPSICPPGP------------PGPPGMPGFKGPTGYKGEQ---GEVGKD 207
            G   EGA       + PPGP            PGP G PG  GPTG KG++   G VG +
Sbjct: 953  G--REGAKG----ELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGAN 1006

Query: 208  GEKGDPGPPGPA---GLPGSVGLQGP---------RGLRGLPGPLGPPGDRGPIGFRGPP 255
            G  G+ GP GPA   GLPG  G +GP         RG RG PGP G  G  GP+G  GPP
Sbjct: 1007 GSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPP 1066

Query: 256  GIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKD---GQNGVP 312
            G  G  G+ GD+G+ G  G +G KGD G  GP G PG+ GP+G PG PG D   G+ G P
Sbjct: 1067 GAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP 1126

Query: 313  GLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGP---------S 363
            GL GQKG+ G  G  G  GP GL GLPG  G KGE G+ G  G  G  GP          
Sbjct: 1127 GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186

Query: 364  GEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL------- 416
            G PG+PG  G PG  GE G RG AG  GP G PG PG +G  G+KG  G  G        
Sbjct: 1187 GTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKK 1246

Query: 417  --PGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGEL 474
              PG  G +G VG  G  G  GP GD G++G DG PG+KG+ G  G  GP G SG  G  
Sbjct: 1247 GPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAP 1306

Query: 475  GPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMIS 534
            GP G +GP+G  G +G  G  G  G  G  G PG TG  G  G                 
Sbjct: 1307 GPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARG----------------- 1349

Query: 535  EQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGP 594
                           PG +G  G  G PGP G PG +G PG  GPPG  GP+G    PG 
Sbjct: 1350 --------------PPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGL---PGL 1392

Query: 595  RGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAI 653
            +G+ G +G+KG  G  GL GP G+ G +G QG+PG          G PGP GDPG PG I
Sbjct: 1393 KGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQ--------GPPGPKGDPGPPGPI 1444

Query: 654  GAQGTPGICDTSACQGAVLGGVGEKSGSRSS 684
            G+ G PG          V G +G+K GS+ S
Sbjct: 1445 GSLGHPG-------PPGVAGPLGQK-GSKGS 1467



 Score =  434 bits (1117), Expect = e-121
 Identities = 258/564 (45%), Positives = 293/564 (51%), Gaps = 71/564 (12%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            GL G PGP G PG PG  G+ G+ GPPG   P G  G+PG+ G  G AG  GLPG  G  
Sbjct: 974  GLRGFPGPKGGPGDPGPTGLKGDKGPPG---PVGANGSPGERGPLGPAGGIGLPGQSGSE 1030

Query: 89   GRDGPPGPKGAPGERGSLGP------PGPPG-LGGKGLPGPPGEAGVSGPPGGIGLRGPP 141
            G  GP G KG+ GERG  GP      PGP G LG  G  GP GE G  G  G  G +G  
Sbjct: 1031 GPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSK 1090

Query: 142  GPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQ 201
            G  G  G PG PG  GP GHPG  P GA   Q       G  GPPG+ G KG  G +G  
Sbjct: 1091 GDKGDAGPPGQPGIRGPAGHPG--PPGADGAQ-------GRRGPPGLFGQKGDDGVRGFV 1141

Query: 202  GEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAP 261
            G +G  G +G PGPPG  G  G VG  GP    G PGP GP G  G  G  G PG  G P
Sbjct: 1142 GVIGPPGLQGLPGPPGEKGEVGDVGSMGP---HGAPGPRGPQGPTGSEGTPGLPGGVGQP 1198

Query: 262  GKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEA 321
            G  G++GERG  G  GP G  G PGPKG  G  G SG  G  G  G+ G PG DG KG  
Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258

Query: 322  GRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEA 381
            G  G PG+ GP G PG+ G  GS GEKG+ G  G  G  G SGEPG PG    PG+RG +
Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGP---PGKRGPS 1315

Query: 382  GH---------RGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL---PGP---QGLRGDV 426
            GH         +G+ G  GP GPPG  G  G +G  G +G  GL   PGP    GL G  
Sbjct: 1316 GHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAP 1375

Query: 427  GDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTS 486
            G  GP G  GP G  G+ G  G  G+KG +G  GL+GP GE+G +G+ G  G QGP    
Sbjct: 1376 GQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGP---P 1432

Query: 487  GVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRK 546
            G +G PGPPGP+G  G PG PG+ G  G  G + S                         
Sbjct: 1433 GPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS------------------------- 1467

Query: 547  PLAPGSIGRPGPAGPPGPPGPPGS 570
               PGS+G  G  GP GPPGPPG+
Sbjct: 1468 ---PGSMGPRGDTGPAGPPGPPGA 1488



 Score =  214 bits (546), Expect = 2e-55
 Identities = 123/260 (47%), Positives = 138/260 (53%), Gaps = 31/260 (11%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA------PGKP 70
            GE  A       GLPG  GPPG PG  G DG  GE G PG  G PGP GA      PG P
Sbjct: 1250 GEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPP 1309

Query: 71   GKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGG----KGLPGPPGEA 126
            GK G +G  G  G +G  G  G PGP G PG  G +G  GPPG  G    +G+PGP GE 
Sbjct: 1310 GKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEP 1369

Query: 127  GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPP 186
            G+ G PG +G  GP GPSGLPGL G  GP G  GH G++               G  GPP
Sbjct: 1370 GLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLI---------------GLIGPP 1414

Query: 187  GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP---RGLRGLPGPLGPP 243
            G  G KG  G  G QG  G  G+ G PGP G  G PG  G+ GP   +G +G PG +GP 
Sbjct: 1415 GEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPR 1474

Query: 244  GDRGPIGFRGPPGIPGAPGK 263
            GD GP    GPPG PGAP +
Sbjct: 1475 GDTGP---AGPPGPPGAPAE 1491



 Score =  176 bits (447), Expect = 5e-44
 Identities = 128/336 (38%), Positives = 147/336 (43%), Gaps = 59/336 (17%)

Query: 358 GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLP 417
           GE G  GEP V  + G   E G  G  G  G +GP GPPG PG  G  G  G  G PG+P
Sbjct: 373 GEKGAKGEPAVI-EKGQQFE-GPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIP 430

Query: 418 GPQGLRGDVGD-------------RGPGGAAGPKGDQGIAGSDGLP--GDKGELGPSGLV 462
           G  G+RG  G              +GP  +      Q +     L   G  G +G +G  
Sbjct: 431 GIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRP 490

Query: 463 GPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASE 522
           GP G  G  G  G +G +GP G  G+QG  GPPG +G  G PG  G  G PG  G +   
Sbjct: 491 GPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGD- 549

Query: 523 QRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGY 582
              R   G                P  PG  G+ G  G  G PGPPG  G  GA GPPG 
Sbjct: 550 ---RGFDG---------------LPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPG- 590

Query: 583 RGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPG 642
             PTG+ G+PGPRG              L GP G  GP G  GV G      DGAPG  G
Sbjct: 591 --PTGQAGEPGPRG--------------LLGPRGSPGPTGRPGVTGI-----DGAPGAKG 629

Query: 643 PPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678
             G PG PG  G QG  G       QG ++G  GEK
Sbjct: 630 NVGPPGEPGPPGQQGNHGSQGLPGPQG-LIGTPGEK 664



 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 60/168 (35%), Positives = 71/168 (42%), Gaps = 22/168 (13%)

Query: 1    MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP 60
            M  P    P  L  L G+         +GL G  GPPG  G+ G  G+ G  GPPG  G 
Sbjct: 1378 MGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGD 1437

Query: 61   PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK--- 117
            PGP G  G  G PG    PG+ G  G  G  G PG  G  G+ G  GPPGPPG   +   
Sbjct: 1438 PGPPGPIGSLGHPGP---PGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHG 1494

Query: 118  --------GLPGPPGEAGVSGPPGGI--------GLRGPPGPSGLPGL 149
                     +P P  E G+      +         LR PPG +  PGL
Sbjct: 1495 LRRRRRFVPVPLPVVEGGLEEVLASLTSLSLELEQLRRPPGTAERPGL 1542


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  521 bits (1343), Expect = e-148
 Identities = 321/752 (42%), Positives = 369/752 (49%), Gaps = 130/752 (17%)

Query: 29   GLPGPPGPPGP------PGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLP 82
            G+PG PG  G       PG PG+ G  G+ G  GLPGPPG  G  G  G+ G  GLPG  
Sbjct: 461  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520

Query: 83   GVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEAG------VSGPPGGI 135
            G  GL G  GPPG  G PG RG  GP GP G LG +G PGPPG+ G      + GP G I
Sbjct: 521  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 580

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGP---PGPPGM--- 188
            G  G  GP G PGLPG PG  GPPGHPG   P G    Q PS  P GP   PGP G+   
Sbjct: 581  GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS-GPQGPLGYPGPRGVKGV 639

Query: 189  ------------------PGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGL------PGS 224
                              PGFKG  G KG++GEVG  G +G+ GP GP G       PG 
Sbjct: 640  DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699

Query: 225  VGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPG---------KAGDRGERGPEGF 275
             GL G +G  G+PG  G PG +GP G  G PG PGA G         K+G RGERGP G 
Sbjct: 700  PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 759

Query: 276  RG------------------------PKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
            RG                        P G+ G PGP+G  G  GP G PG PGKDG  G 
Sbjct: 760  RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 819

Query: 312  PG------------------------LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE 347
            PG                          G+ G  G  G PG  GP G  GLPG AG +G 
Sbjct: 820  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879

Query: 348  KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ 407
            KG+ G  G  G+ GP+G  G PG+ G+PG  G  G +G+ G  GP GP G+PG RG  G 
Sbjct: 880  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939

Query: 408  KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE 467
             G +G PG PGPQG  G  G++G  G  GP G     G DG+ G  G  GP+G  G  GE
Sbjct: 940  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP---TGRDGVQGPVGLPGPAGPPGVAGE 996

Query: 468  SGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SE 522
             G +GE+G  G +G  G  G  G PGPPGP+G  G PG  G  G+PG  G +       +
Sbjct: 997  DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD 1056

Query: 523  QRIRELCG--GMISEQIAQLAAHLRKPLA-PGSIGRPGPAGPPGPPGPPGSIGHPGARGP 579
            +  R   G  G I  Q       L  P    G  G  GP GPPGPPGP G  G  GA GP
Sbjct: 1057 EGTRGFNGPPGPIGLQ------GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1110

Query: 580  PGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPG---------- 628
             G  G  G LG PG +G  G+ G  G  G  G+ GP G++G +G  G PG          
Sbjct: 1111 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1170

Query: 629  TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            T  DG  G PG  G PGDPG PG  G +G  G
Sbjct: 1171 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG 1202



 Score =  504 bits (1298), Expect = e-142
 Identities = 310/737 (42%), Positives = 353/737 (47%), Gaps = 117/737 (15%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            GLPG PG  GPPG PG++G  G  G  G  GP GP G PG  G  G  G+ GL G  G  
Sbjct: 593  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 652

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP-GPPGEAGVSGPPGGIGLRGPPGPSGLP 147
            G DG PG KG  G +G  G  G PG  G+  P GP G  G +G PG  GL G  G  G+P
Sbjct: 653  GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVP 712

Query: 148  GLPGPPGPPGP------PGHPGVLPE-GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGE 200
            GLPG PG  GP      PG PG   E GA  L        G  GP G  G  GP G +G 
Sbjct: 713  GLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS-------GKSGPRGERGPTGPRGQRGP 765

Query: 201  QGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG------------DRGP 248
            +G  GK G KG  G  GP G PG  GL GP+G  G PGP GPPG             RG 
Sbjct: 766  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 825

Query: 249  IGFRG---PPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGE------ 299
            +GF+G   PPG PG  G  G  GE GP G RG  G  G PG +G PG AG  G       
Sbjct: 826  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 885

Query: 300  PGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG- 358
            PG PGKDG  G+ G  G++G  G  G PG KG  G  G PG AGS GE+G  G  G +G 
Sbjct: 886  PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 945

Query: 359  --EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGP---QGPPGAPGVRGFQGQKGSMGD 413
                GP G PG  G+ G+PGE+G  G  G  G  GP    GP G PGV G  G KG +GD
Sbjct: 946  PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1005

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE------------------ 455
            PG  G +G +G+ G  GP G  GP G  G AG+DG PG +G                   
Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1065

Query: 456  ---LGPSGLVGPKGESGSRGELGP---------KGTQGPNGTSGVQGVPG------PPGP 497
               +G  GL GP GE G  G++GP         +G  GPNG  G QG PG      PPG 
Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1125

Query: 498  LGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPG 557
             G  G  G PGI G+PGV G         E                  +P  PG  G  G
Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGES----------------GQPGEPGPPGPKG 1169

Query: 558  PAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEG 616
            P G  GP G PG +G PG  GPPG  GP G+ G  G RG  G+ G  G+ G  G +GP G
Sbjct: 1170 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1229

Query: 617  DQGPQGPQGVPG----------------------TSKDGQDGAPGEPGPPGDPGLPGAIG 654
              G +GP G PG                      T   G  G  G+PGP G  GLPG++G
Sbjct: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289

Query: 655  AQGTPGICDTSACQGAV 671
             QG PG    +   G V
Sbjct: 1290 QQGRPGATGQAGPPGPV 1306



 Score =  504 bits (1297), Expect = e-142
 Identities = 300/673 (44%), Positives = 337/673 (50%), Gaps = 76/673 (11%)

Query: 27   RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDG 86
            R G  G PGPPG  G+ G+ G+ G  G PG  GP G  G PG PG  GE G  GL G  G
Sbjct: 690  RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSG 749

Query: 87   LTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSG 145
              G  GP GP+G  G RG+ G  G  G  GG G  GPPGE G+ GP G  G  GP GP  
Sbjct: 750  PRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-- 807

Query: 146  LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205
                PGPPG  G PGHPG    G    Q       G  GPPG PG  GP G  GE G +G
Sbjct: 808  ----PGPPGKDGLPGHPG--QRGEVGFQ-------GKTGPPGPPGVVGPQGAAGETGPMG 854

Query: 206  KDGEKGDPGPPGPAGLPGSVGLQ---------------GPRGLRGLPGPLGPPGDRGPIG 250
            + G  G PGPPG  GLPG+ G +               GP GLRG PG  G PG  G  G
Sbjct: 855  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPG 914

Query: 251  FRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMP---GKDG 307
             +G  G  G PG AG  GERG  G  GP G  GRPGP+G PG AG  G PG     G  G
Sbjct: 915  LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 974

Query: 308  QNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPG 367
            ++GV G  G  G AG  G  GE G  G  G PG+ G+KG KGE G  G  G  GP G+PG
Sbjct: 975  RDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1034

Query: 368  VPGDAGMPGERGEAGH------RGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQG 421
              G  G PG RG  GH       G+ G  GP GP G  G+ G  G+KG  GD G  GP G
Sbjct: 1035 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1094

Query: 422  LRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQG 481
              G  G  GP GA GP+G  G  G+ G PG+KGE G SG  G +GE G +G  G +G +G
Sbjct: 1095 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1154

Query: 482  PNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLA 541
             +G  G  G PGP GP G  G  G PG  G PG PG            GG   +      
Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE--------GGPRGQD----- 1201

Query: 542  AHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDR 601
                     G+ G  G  G PG PG PG  G  G  GP G RGP G  G  G +G +G +
Sbjct: 1202 ---------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAK 1252

Query: 602  GDKGAAGA-------GLDGPEGDQGPQGPQGVPGT-------SKDGQDGAPGEPGPPGDP 647
            GD GA GA       G  GP G  GP G +G+PG+          GQ G PG  GPPG P
Sbjct: 1253 GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1312

Query: 648  GLPGAIGAQGTPG 660
            GL G  GA+G  G
Sbjct: 1313 GLRGDAGAKGEKG 1325



 Score =  502 bits (1292), Expect = e-142
 Identities = 316/725 (43%), Positives = 367/725 (50%), Gaps = 110/725 (15%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA---PGKPGKPGEAGLPGLPGVD 85
            G  GP G PGPPG  G+ G  G  G PG PG  GPKG+   PG PG  GE G  GL G  
Sbjct: 689  GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKS 748

Query: 86   GLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGL---RGPP 141
            G  G  GP GP+G  G RG+ G  G  G  GG G  GPPGE G+ GP G  G    +GPP
Sbjct: 749  GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 808

Query: 142  GPSGLPGLPGPPGP---------PGPPGHPGVL-PEGATDLQCPS-----ICPPGPPGPP 186
            GP G  GLPG PG           GPPG PGV+ P+GA     P        PPGPPG  
Sbjct: 809  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 868

Query: 187  GMPGFKGPTGYKGEQGEVG---KDGEKGDPGPPGPAGLPGSVG---LQGPRGLRGLPGPL 240
            G+PG  G  G KG+ G  G   KDG  G  G PG  GLPG+ G   L+G  G  G PGP 
Sbjct: 869  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 928

Query: 241  GPPGDRGPIGFRGP---PGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPS 297
            G PG+RG  G  GP   PG PG  G  G  GE+G  G +GP G  GR G +G  G+ GP+
Sbjct: 929  GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA 988

Query: 298  GEPGMPGKDGQNGV---PGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRA 354
            G PG+ G+DG  G    PG  G KG  G +G PG  GP G  G PG AG+ GE G RG  
Sbjct: 989  GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1048

Query: 355  GELGEAG---------------------PSGEPGVPGDAGMPGERGEAGHRGSAG---AL 390
            G  G  G                     PSGE G  GD G  G  G  G RG AG   A 
Sbjct: 1049 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1108

Query: 391  GPQGPPGA------PGVRGFQGQKGS---MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQ 441
            GPQGPPG       PG +G  G+ GS    G+PG+ GP+G RG+ G+ G  G  GP G +
Sbjct: 1109 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1168

Query: 442  GIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGP------P 495
            G  G DG  G+ G +G  G  GP GE G RG+ G KG +G +G  G  G PGP      P
Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1228

Query: 496  GPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGR 555
            GPLG +G  G PG  G+ G  G +     I                       APG  G 
Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG----------------------APGKTGP 1266

Query: 556  PGPAGPPGPPGP------PGSIGH---PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGA 606
             GPAGP G PGP      PGS+G    PGA G  G  GP G  G PG RG+ G +G+KG 
Sbjct: 1267 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1326

Query: 607  AGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTS 665
             G  GL GP G+QG +G +G+PG       G+PG+ G  G PG  G IG  G PG+   +
Sbjct: 1327 PGLIGLIGPPGEQGEKGDRGLPGPQ-----GSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1381

Query: 666  ACQGA 670
              +GA
Sbjct: 1382 GPKGA 1386



 Score =  500 bits (1287), Expect = e-141
 Identities = 310/729 (42%), Positives = 347/729 (47%), Gaps = 95/729 (13%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            G++        VG+PG  G  GP G  G+ G  G+ GPPGL G  G  G PG PG PG  
Sbjct: 662  GDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 721

Query: 77   G------LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPG---PPGLGGK-GLPGPPGEA 126
            G       PG PG  G  G  G  G  G  GERG  GP G   P G  GK G  G  G  
Sbjct: 722  GPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 781

Query: 127  GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGP---PGHPGVLPEGATDLQCPSICPPGPP 183
            G  GPPG  GL GP GP+G PG  GPPGPPG    PGHPG    G    Q       G  
Sbjct: 782  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG--QRGEVGFQ-------GKT 832

Query: 184  GPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQG-------------- 229
            GPPG PG  GP G  GE G +G+ G  G PGPPG  GLPG+ G +G              
Sbjct: 833  GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 892

Query: 230  -PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPK 288
             P GLRG PG  G PG  G  G +G  G  G PG AG  GERG  G  GP G  GRPGP+
Sbjct: 893  GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 952

Query: 289  GTPGVAGPSGEPGMPGK---DGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G PG AG  G PG  G     G++GV G  G  G AG  G  GE G  G  G PG+ G+K
Sbjct: 953  GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1012

Query: 346  GEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH------RGSAGALGPQGPPGAP 399
            G KGE G  G  G  GP G+PG  G  G PG RG  GH       G+ G  GP GP G  
Sbjct: 1013 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1072

Query: 400  GVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPS 459
            G+ G  G+KG  GD G  GP G  G  G  GP GA GP+G  G  G+ G PG+KGE G S
Sbjct: 1073 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1132

Query: 460  GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE 519
            G  G +GE G +G  G +G +G +G  G  G PGP GP G  G  G PG  G PG PG  
Sbjct: 1133 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP 1192

Query: 520  ASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGP------------ 567
                      GG   +  A+      +   PG  G PGP G  GPPGP            
Sbjct: 1193 GE--------GGPRGQDGAK--GDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1242

Query: 568  ------------PGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPE 615
                        PG+IG PG  GP G  GP G+ G  G RG  G  G +G  GA   G  
Sbjct: 1243 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGA--TGQA 1300

Query: 616  GDQGPQGPQGVPGTSKD-------------GQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662
            G  GP GP G+PG   D             G  G PGE G  GD GLPG  G+ G  G  
Sbjct: 1301 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1360

Query: 663  DTSACQGAV 671
                  G +
Sbjct: 1361 GIPGASGPI 1369



 Score =  486 bits (1250), Expect = e-137
 Identities = 297/675 (44%), Positives = 341/675 (50%), Gaps = 68/675 (10%)

Query: 32  GPPGPPGPPGKPGQDGIDGEAGP---PGLPGPPGPKGAPGKPGKPGEAGLP-GLPGVDGL 87
           GPPGP GP G  G  GI G  GP   PG  GPPG  G PG  G PG  G    LP   G 
Sbjct: 313 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 372

Query: 88  TGRD------------------------GPPGPKGAPGERGSLGPPGPPGLGGKGLPGPP 123
            G D                        GPPGP G  G  G LG PG PGL G+      
Sbjct: 373 GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES----- 427

Query: 124 GEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPP 183
           G+ G  GP G  GL GPPG +G  G  G  G  G PG PGV  +   D         G P
Sbjct: 428 GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFD---------GLP 478

Query: 184 GPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPP 243
           G PG  G +G TG +G  G  G+DGE+GD G  GP GLPG     GPRGL    GP GPP
Sbjct: 479 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE---SGPRGLL---GPKGPP 532

Query: 244 GDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT---PGVAGPSGEP 300
           G  GP G RG  G  G  G  G +GE GP G +G  G  G PGP+G     G  GP G+P
Sbjct: 533 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 592

Query: 301 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA 360
           G+PG  G +G PG  G++G  G  G  G  GP G  G PG  G KG  G RG  G  GE 
Sbjct: 593 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 652

Query: 361 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP---------PGAPGVRGFQGQKGSM 411
           G  G PG  GD G+ G+RGE G  GS G  GP+GP         PG PG+ G +G+ G  
Sbjct: 653 GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVP 712

Query: 412 GDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR 471
           G PG PG QG +G +G  G  GA+G KG +G++G  G  G++G  GP G  GP+G +G  
Sbjct: 713 GLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772

Query: 472 GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK--EASEQRIRELC 529
           G  G  G  GP+G  G +G+PGP GP G  G  G PG  GK G+PG   +  E   +   
Sbjct: 773 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 832

Query: 530 G--GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTG 587
           G  G       Q AA    P+  G  G PGP GPPG  G PG+ G  G +G PG  G  G
Sbjct: 833 GPPGPPGVVGPQGAAGETGPM--GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890

Query: 588 ELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGAP-GEPGPPG 645
           + G  G RG  G+RG  G AG  GL G EG  GP GP G PG       G P G PG PG
Sbjct: 891 KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 950

Query: 646 DPGLPGAIGAQGTPG 660
             G PGA G +G PG
Sbjct: 951 PQGPPGAAGEKGVPG 965



 Score =  474 bits (1221), Expect = e-134
 Identities = 285/653 (43%), Positives = 323/653 (49%), Gaps = 74/653 (11%)

Query: 29   GLPGPPGPPGPPGK------PGQDG---IDGEAGPPGLPGPPGPKGA------------P 67
            G PGP GPPGPPGK      PGQ G     G+ GPPG PG  GP+GA            P
Sbjct: 800  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 859

Query: 68   GKPGKPGEAGLPGL---------PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGK 117
            G PG PGE GLPG          PG  G  G+DGP G +G PGERG  G  G PGL G +
Sbjct: 860  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 919

Query: 118  GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG----VLPEGATDLQ 173
            G  GPPG AG  G  G  G  GP GP G PG  GPPG  G  G PG    + P G   +Q
Sbjct: 920  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979

Query: 174  CPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGL 233
             P +  PGP GPPG+ G  G  G  G+ G+ G  G KG+ GPPGP G  G VG  G  G 
Sbjct: 980  GP-VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1038

Query: 234  RGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGV 293
             G PG  GP G  G  G  G  G  G PG  G +G  GP G +G  GD+G  GP G PG 
Sbjct: 1039 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1098

Query: 294  AGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGR 353
             GP+         G NG  G  G  G  G  G PGEKG  G  G PG  G  G KG RG 
Sbjct: 1099 RGPA---------GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE 1149

Query: 354  AGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGD 413
             GE GE+G  GEPG PG  G  G+ G  G+ G  G  G  GPPG  G RG  G KG  G+
Sbjct: 1150 RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGE 1209

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGE 473
             G PG  G  G  G+ GP G  G +G  G  GS+G  G KG  G  G +G  G++G  G 
Sbjct: 1210 DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGP 1269

Query: 474  LGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMI 533
             GP G  GP+G  G+ G  G  G  G  G  G PG  G PG+PG       +R   G   
Sbjct: 1270 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG-------LRGDAGAKG 1322

Query: 534  SEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPG 593
             +    L   +  P   G  G  G  GP G PG  G +G PGA GP G  GP G  G  G
Sbjct: 1323 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAG 1382

Query: 594  PRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD 646
            P      +G KGA G G  GP+G++G QGP              PG PGPPG+
Sbjct: 1383 P------KGAKGATGPG--GPKGEKGVQGP--------------PGHPGPPGE 1413



 Score =  453 bits (1166), Expect = e-127
 Identities = 275/651 (42%), Positives = 319/651 (49%), Gaps = 78/651 (11%)

Query: 25   AQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK------PGEAGL 78
            A   G  G  G PGPPG PG+ G+ G AG  G  G PGP GAPGK G       PGE GL
Sbjct: 847  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 906

Query: 79   PGL---PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
            PG    PG+ G  G  GPPGP G+PGERG+ G  GP  +G  G PGP G  G +G  G  
Sbjct: 907  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP--IGPPGRPGPQGPPGAAGEKGVP 964

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEG------------ATDLQCPSICPPGPP 183
            G +GP GP+G  G+ GP G PGP G PGV  E              T        PPGPP
Sbjct: 965  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1024

Query: 184  GP------PGMPGFKGPTGYKGEQGEVGKDGEKGD---PGPPGPAGLPGSVGLQGPRGLR 234
            GP      PG  G  G  G +G QG  G  G++G     GPPGP GL G  G  G +G  
Sbjct: 1025 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084

Query: 235  GLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVA 294
            G  GP+GPPG  GP G  GP G  G  G  G  G  GP G +G  G+ G PG +G PGV 
Sbjct: 1085 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1144

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRA 354
            GP GE G  G+ GQ G PG  G KG  G +G  G  GP G PG PG  G  G +G+ G  
Sbjct: 1145 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1204

Query: 355  GELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDP 414
            G+ GE G  G+PG P         G  G  G  G LG +GP G+PG  G QG KG+ GDP
Sbjct: 1205 GDRGEDGEPGQPGSP---------GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1255

Query: 415  GLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGS---DGLPGDKGELGPSGLVGPKGESGSR 471
            G  G  G  G VG  GP G  GP G +G+ GS    G PG  G+ GP G VGP G  G R
Sbjct: 1256 GAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1315

Query: 472  GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGG 531
            G+ G KG +   G  G+ G+ GPPG  G +G  G+PG  G PG  G+             
Sbjct: 1316 GDAGAKGEK---GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE------------- 1359

Query: 532  MISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGD 591
                        +  P A G IG  GP G PGP GP G+ G  G  GP G +G  G  G 
Sbjct: 1360 ------------MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1407

Query: 592  PGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPG 642
            PGP G                  +G +  Q  + +P        GAPG PG
Sbjct: 1408 PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP------TGGAPGSPG 1452



 Score =  394 bits (1011), Expect = e-109
 Identities = 240/560 (42%), Positives = 283/560 (50%), Gaps = 56/560 (10%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            GE  AA     +G PG PGP GPPG  G+ G+ GE GP    GP G  G  G  G PG A
Sbjct: 932  GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP---IGPTGRDGVQGPVGLPGPA 988

Query: 77   GLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG----LGGKGLPGPPGEAGVSGPP 132
            G PG+ G DG  G  G PG KG  G +G  GPPGPPG    +G  G  G  GE G  GP 
Sbjct: 989  GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1048

Query: 133  GGIGLR---------GPPGPSGLPGLPGPP------------GPPGPPGHPGVL-PEGAT 170
            G  G +         GPPGP GL GLPGP             GPPGPPG  G   P GA 
Sbjct: 1049 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA- 1107

Query: 171  DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP 230
                      GP GPPG  G  GP G KGE GE G  G +G+PG  GP G  G  G  G 
Sbjct: 1108 ---------DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1158

Query: 231  RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT 290
             G  G PGP GP GD GP G  GP G PG PG  G+ G RG +G +G +G+ G PG  G+
Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1218

Query: 291  PGVAGPSGEPGMPGKDGQNGVPGLDGQ------KGEAGRNGAPGEKGPNGLPGLPGRAGS 344
            PG  G +G PG  GK G  G PG +G+      KG+ G  GAPG+ GP G  G  G+ G 
Sbjct: 1219 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1278

Query: 345  KGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGF 404
             G +G  G  G+ G  G +G+ G PG  G P   G  G RG AGA G +G PG  G+ G 
Sbjct: 1279 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPP---GLPGLRGDAGAKGEKGHPGLIGLIGP 1335

Query: 405  QGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGP 464
             G++G  GD GLPGPQG  G  G+ G  GA+GP G     G  GLPG  G  G  G  GP
Sbjct: 1336 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP---GGPPGLPGPAGPKGAKGATGP 1392

Query: 465  KGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVP--GKEASE 522
             G  G +G  GP G  GP G   +Q +P        + V G   +     +P  G   S 
Sbjct: 1393 GGPKGEKGVQGPPGHPGPPG-EVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1451

Query: 523  QRIRELCGGM--ISEQIAQL 540
              + E+ G +  + E+I Q+
Sbjct: 1452 GGLEEIFGSLDSLREEIEQM 1471



 Score =  211 bits (537), Expect = 2e-54
 Identities = 146/390 (37%), Positives = 174/390 (44%), Gaps = 70/390 (17%)

Query: 303 PGKDGQNGVPGLDGQKGEAGR-------NGAPGEKGPNGL---PGLPGRAGSKGEKGERG 352
           P ++  +G  GL G+KGE           G PG +GP GL   PG+ G  G  G+ GERG
Sbjct: 284 PLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 343

Query: 353 RAGELGEAGPSGEPGVPGDAGM--------PGERGE--AGHRGSAGALGPQGP---PGAP 399
             G  G  G  G PG PG + M         G++G   A     A A+  Q      G P
Sbjct: 344 PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 403

Query: 400 GVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPS 459
           G  G+ G+ G +G PG PG +G  GD+G +GP G  G  G  G AG  G  G  G  G  
Sbjct: 404 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 463

Query: 460 GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE 519
           G  G KG+ G  G  G  G +G  G +G QG+PGPPG  G +G  G  G  G PG  G  
Sbjct: 464 GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR 523

Query: 520 ASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGP 579
                                             G  GP GPPG PGPPG  G  G +GP
Sbjct: 524 ----------------------------------GLLGPKGPPGIPGPPGVRGMDGPQGP 549

Query: 580 PGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPG 639
            G  GP GE G PG +G  G +G  G  GA   GP G++GPQG  G+PG           
Sbjct: 550 KGSLGPQGEPGPPGQQGTPGTQGLPGPQGA--IGPHGEKGPQGKPGLPGM---------- 597

Query: 640 EPGPPGDPGLPGAIGAQGTPGICDTSACQG 669
            PG  G PG PG  G  GT G    S  QG
Sbjct: 598 -PGSDGPPGHPGKEGPPGTKGNQGPSGPQG 626



 Score =  166 bits (420), Expect = 7e-41
 Identities = 127/347 (36%), Positives = 145/347 (41%), Gaps = 81/347 (23%)

Query: 369 PGDAGMPGERGEAGHRGSAGALGP----QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG 424
           P +    G RG  G +G    L P    +GPPG       +G  G +G PG+ G  G  G
Sbjct: 284 PLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP------EGPAGLIGPPGIQGNPGPVG 337

Query: 425 DVGDRGPGGAAGPKGDQGIAGSDG----LP-------GDKGELGPS-------------- 459
           D G+RGP G AG  G  G  G  G    LP       GDKG +  +              
Sbjct: 338 DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 397

Query: 460 GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE 519
            L GP G  G  G  GP G  G  G  G  G  GP GP G QG+ G PG  G+ G  G  
Sbjct: 398 ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG-- 455

Query: 520 ASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGP 579
                                        A G+ G PG    PG  G  G  G PG  G 
Sbjct: 456 -----------------------------ADGARGMPGD---PGVKGDRGFDGLPGLPGE 483

Query: 580 PGYRGPTGELGDPGPRGNQGDRGDKGAAGA----GLDGPEGDQGPQGPQGVPGT----SK 631
            G+RG TG  G PGP G  G+RGD G  G     G  GP G  GP+GP G+PG       
Sbjct: 484 KGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM 543

Query: 632 DGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678
           DG  G  G  GP G+PG PG    QGTPG       QGA+ G  GEK
Sbjct: 544 DGPQGPKGSLGPQGEPGPPGQ---QGTPGTQGLPGPQGAI-GPHGEK 586


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  521 bits (1343), Expect = e-148
 Identities = 321/752 (42%), Positives = 369/752 (49%), Gaps = 130/752 (17%)

Query: 29   GLPGPPGPPGP------PGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLP 82
            G+PG PG  G       PG PG+ G  G+ G  GLPGPPG  G  G  G+ G  GLPG  
Sbjct: 440  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499

Query: 83   GVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEAG------VSGPPGGI 135
            G  GL G  GPPG  G PG RG  GP GP G LG +G PGPPG+ G      + GP G I
Sbjct: 500  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 559

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGP---PGPPGM--- 188
            G  G  GP G PGLPG PG  GPPGHPG   P G    Q PS  P GP   PGP G+   
Sbjct: 560  GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS-GPQGPLGYPGPRGVKGV 618

Query: 189  ------------------PGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGL------PGS 224
                              PGFKG  G KG++GEVG  G +G+ GP GP G       PG 
Sbjct: 619  DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 678

Query: 225  VGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPG---------KAGDRGERGPEGF 275
             GL G +G  G+PG  G PG +GP G  G PG PGA G         K+G RGERGP G 
Sbjct: 679  PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 738

Query: 276  RG------------------------PKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
            RG                        P G+ G PGP+G  G  GP G PG PGKDG  G 
Sbjct: 739  RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 798

Query: 312  PG------------------------LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE 347
            PG                          G+ G  G  G PG  GP G  GLPG AG +G 
Sbjct: 799  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858

Query: 348  KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ 407
            KG+ G  G  G+ GP+G  G PG+ G+PG  G  G +G+ G  GP GP G+PG RG  G 
Sbjct: 859  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918

Query: 408  KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE 467
             G +G PG PGPQG  G  G++G  G  GP G     G DG+ G  G  GP+G  G  GE
Sbjct: 919  GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP---TGRDGVQGPVGLPGPAGPPGVAGE 975

Query: 468  SGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SE 522
             G +GE+G  G +G  G  G  G PGPPGP+G  G PG  G  G+PG  G +       +
Sbjct: 976  DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD 1035

Query: 523  QRIRELCG--GMISEQIAQLAAHLRKPLA-PGSIGRPGPAGPPGPPGPPGSIGHPGARGP 579
            +  R   G  G I  Q       L  P    G  G  GP GPPGPPGP G  G  GA GP
Sbjct: 1036 EGTRGFNGPPGPIGLQ------GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1089

Query: 580  PGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPG---------- 628
             G  G  G LG PG +G  G+ G  G  G  G+ GP G++G +G  G PG          
Sbjct: 1090 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1149

Query: 629  TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            T  DG  G PG  G PGDPG PG  G +G  G
Sbjct: 1150 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG 1181



 Score =  504 bits (1298), Expect = e-142
 Identities = 310/737 (42%), Positives = 353/737 (47%), Gaps = 117/737 (15%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            GLPG PG  GPPG PG++G  G  G  G  GP GP G PG  G  G  G+ GL G  G  
Sbjct: 572  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 631

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP-GPPGEAGVSGPPGGIGLRGPPGPSGLP 147
            G DG PG KG  G +G  G  G PG  G+  P GP G  G +G PG  GL G  G  G+P
Sbjct: 632  GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVP 691

Query: 148  GLPGPPGPPGP------PGHPGVLPE-GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGE 200
            GLPG PG  GP      PG PG   E GA  L        G  GP G  G  GP G +G 
Sbjct: 692  GLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS-------GKSGPRGERGPTGPRGQRGP 744

Query: 201  QGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG------------DRGP 248
            +G  GK G KG  G  GP G PG  GL GP+G  G PGP GPPG             RG 
Sbjct: 745  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 804

Query: 249  IGFRG---PPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGE------ 299
            +GF+G   PPG PG  G  G  GE GP G RG  G  G PG +G PG AG  G       
Sbjct: 805  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 864

Query: 300  PGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG- 358
            PG PGKDG  G+ G  G++G  G  G PG KG  G  G PG AGS GE+G  G  G +G 
Sbjct: 865  PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 924

Query: 359  --EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGP---QGPPGAPGVRGFQGQKGSMGD 413
                GP G PG  G+ G+PGE+G  G  G  G  GP    GP G PGV G  G KG +GD
Sbjct: 925  PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 984

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE------------------ 455
            PG  G +G +G+ G  GP G  GP G  G AG+DG PG +G                   
Sbjct: 985  PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1044

Query: 456  ---LGPSGLVGPKGESGSRGELGP---------KGTQGPNGTSGVQGVPG------PPGP 497
               +G  GL GP GE G  G++GP         +G  GPNG  G QG PG      PPG 
Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1104

Query: 498  LGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPG 557
             G  G  G PGI G+PGV G         E                  +P  PG  G  G
Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGES----------------GQPGEPGPPGPKG 1148

Query: 558  PAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEG 616
            P G  GP G PG +G PG  GPPG  GP G+ G  G RG  G+ G  G+ G  G +GP G
Sbjct: 1149 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1208

Query: 617  DQGPQGPQGVPG----------------------TSKDGQDGAPGEPGPPGDPGLPGAIG 654
              G +GP G PG                      T   G  G  G+PGP G  GLPG++G
Sbjct: 1209 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1268

Query: 655  AQGTPGICDTSACQGAV 671
             QG PG    +   G V
Sbjct: 1269 QQGRPGATGQAGPPGPV 1285



 Score =  504 bits (1297), Expect = e-142
 Identities = 300/673 (44%), Positives = 337/673 (50%), Gaps = 76/673 (11%)

Query: 27   RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDG 86
            R G  G PGPPG  G+ G+ G+ G  G PG  GP G  G PG PG  GE G  GL G  G
Sbjct: 669  RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSG 728

Query: 87   LTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSG 145
              G  GP GP+G  G RG+ G  G  G  GG G  GPPGE G+ GP G  G  GP GP  
Sbjct: 729  PRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-- 786

Query: 146  LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205
                PGPPG  G PGHPG    G    Q       G  GPPG PG  GP G  GE G +G
Sbjct: 787  ----PGPPGKDGLPGHPG--QRGEVGFQ-------GKTGPPGPPGVVGPQGAAGETGPMG 833

Query: 206  KDGEKGDPGPPGPAGLPGSVGLQ---------------GPRGLRGLPGPLGPPGDRGPIG 250
            + G  G PGPPG  GLPG+ G +               GP GLRG PG  G PG  G  G
Sbjct: 834  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPG 893

Query: 251  FRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMP---GKDG 307
             +G  G  G PG AG  GERG  G  GP G  GRPGP+G PG AG  G PG     G  G
Sbjct: 894  LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 953

Query: 308  QNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPG 367
            ++GV G  G  G AG  G  GE G  G  G PG+ G+KG KGE G  G  G  GP G+PG
Sbjct: 954  RDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1013

Query: 368  VPGDAGMPGERGEAGH------RGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQG 421
              G  G PG RG  GH       G+ G  GP GP G  G+ G  G+KG  GD G  GP G
Sbjct: 1014 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1073

Query: 422  LRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQG 481
              G  G  GP GA GP+G  G  G+ G PG+KGE G SG  G +GE G +G  G +G +G
Sbjct: 1074 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133

Query: 482  PNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLA 541
             +G  G  G PGP GP G  G  G PG  G PG PG            GG   +      
Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE--------GGPRGQD----- 1180

Query: 542  AHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDR 601
                     G+ G  G  G PG PG PG  G  G  GP G RGP G  G  G +G +G +
Sbjct: 1181 ---------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAK 1231

Query: 602  GDKGAAGA-------GLDGPEGDQGPQGPQGVPGT-------SKDGQDGAPGEPGPPGDP 647
            GD GA GA       G  GP G  GP G +G+PG+          GQ G PG  GPPG P
Sbjct: 1232 GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1291

Query: 648  GLPGAIGAQGTPG 660
            GL G  GA+G  G
Sbjct: 1292 GLRGDAGAKGEKG 1304



 Score =  500 bits (1287), Expect = e-141
 Identities = 310/729 (42%), Positives = 347/729 (47%), Gaps = 95/729 (13%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            G++        VG+PG  G  GP G  G+ G  G+ GPPGL G  G  G PG PG PG  
Sbjct: 641  GDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 700

Query: 77   G------LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPG---PPGLGGK-GLPGPPGEA 126
            G       PG PG  G  G  G  G  G  GERG  GP G   P G  GK G  G  G  
Sbjct: 701  GPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 760

Query: 127  GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGP---PGHPGVLPEGATDLQCPSICPPGPP 183
            G  GPPG  GL GP GP+G PG  GPPGPPG    PGHPG    G    Q       G  
Sbjct: 761  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG--QRGEVGFQ-------GKT 811

Query: 184  GPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQG-------------- 229
            GPPG PG  GP G  GE G +G+ G  G PGPPG  GLPG+ G +G              
Sbjct: 812  GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 871

Query: 230  -PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPK 288
             P GLRG PG  G PG  G  G +G  G  G PG AG  GERG  G  GP G  GRPGP+
Sbjct: 872  GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 931

Query: 289  GTPGVAGPSGEPGMPGK---DGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G PG AG  G PG  G     G++GV G  G  G AG  G  GE G  G  G PG+ G+K
Sbjct: 932  GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 991

Query: 346  GEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH------RGSAGALGPQGPPGAP 399
            G KGE G  G  G  GP G+PG  G  G PG RG  GH       G+ G  GP GP G  
Sbjct: 992  GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1051

Query: 400  GVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPS 459
            G+ G  G+KG  GD G  GP G  G  G  GP GA GP+G  G  G+ G PG+KGE G S
Sbjct: 1052 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1111

Query: 460  GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE 519
            G  G +GE G +G  G +G +G +G  G  G PGP GP G  G  G PG  G PG PG  
Sbjct: 1112 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP 1171

Query: 520  ASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGP------------ 567
                      GG   +  A+      +   PG  G PGP G  GPPGP            
Sbjct: 1172 GE--------GGPRGQDGAK--GDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1221

Query: 568  ------------PGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPE 615
                        PG+IG PG  GP G  GP G+ G  G RG  G  G +G  GA   G  
Sbjct: 1222 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGA--TGQA 1279

Query: 616  GDQGPQGPQGVPGTSKD-------------GQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662
            G  GP GP G+PG   D             G  G PGE G  GD GLPG  G+ G  G  
Sbjct: 1280 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1339

Query: 663  DTSACQGAV 671
                  G +
Sbjct: 1340 GIPGASGPI 1348



 Score =  499 bits (1284), Expect = e-141
 Identities = 310/728 (42%), Positives = 356/728 (48%), Gaps = 100/728 (13%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA---PGKPGKPGEAGLPGLPGVD 85
            G  GP G PGPPG  G+ G  G  G PG PG  GPKG+   PG PG  GE G  GL G  
Sbjct: 668  GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKS 727

Query: 86   GLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGL---RGPP 141
            G  G  GP GP+G  G RG+ G  G  G  GG G  GPPGE G+ GP G  G    +GPP
Sbjct: 728  GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 787

Query: 142  GPSGLPGLPGPPGP---------PGPPGHPGVL-PEGATDLQCPS-----ICPPGPPG-- 184
            GP G  GLPG PG           GPPG PGV+ P+GA     P        PPGPPG  
Sbjct: 788  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847

Query: 185  ----------------PPGMPGFKGPTGYKGEQGEVGKDGEKGDPG---------PPGPA 219
                            PPG PG  GP G +G  GE G  G  G PG         PPGPA
Sbjct: 848  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 907

Query: 220  GLPG---SVGLQGPRGLRGLPGPLGPPGD---------------------RGPIGFRGPP 255
            G PG   + G  GP G  G PGP GPPG                      +GP+G  GP 
Sbjct: 908  GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA 967

Query: 256  GIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLD 315
            G PG  G+ GD+GE G  G +G KG+ G  GP G PG  GP G+PG  G DG+ G  G  
Sbjct: 968  GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1027

Query: 316  GQ---KGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGE------------RGRAGELGEA 360
            G    KG+ G  G  G  GP GL GLPG +G KGE G+            RG AG  G  
Sbjct: 1028 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1087

Query: 361  GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420
            GP G PG  G+ G PGE+GE G  GS G    QG PG  G RG +G+KG  G PG PGP 
Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGI---QGEPGVKGPRGERGEKGESGQPGEPGPP 1144

Query: 421  GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480
            G +G  GD GP G  GP G  G  G  G  G +G+ G  G  G  GE G  G  GP G  
Sbjct: 1145 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1204

Query: 481  GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL 540
            GP G  G +G  G PG  G QG  G  G  G  G PGK           G    + +  L
Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP-AGKPGPDGLRGL 1263

Query: 541  AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD 600
               + +   PG+ G+ GP GP GPPG PG  G  GA+G  G+ G  G +G PG +G +GD
Sbjct: 1264 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1323

Query: 601  RGDKGAAGA-------GLDGPEGDQGPQGPQGVPGTS-KDGQDGAPGEPGPPGDPGLPGA 652
            RG  G  G+       G+ G  G  GP GP G+PG +   G  GA G  GP G+ G+ G 
Sbjct: 1324 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1383

Query: 653  IGAQGTPG 660
             G  G PG
Sbjct: 1384 PGHPGPPG 1391



 Score =  487 bits (1253), Expect = e-137
 Identities = 295/684 (43%), Positives = 341/684 (49%), Gaps = 86/684 (12%)

Query: 32  GPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRD 91
           GPPGP GP G           GPPG+ G PGP G PG+ G PG AGLPG  G  G  G  
Sbjct: 292 GPPGPEGPAGL---------IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTS 342

Query: 92  -------------------------------------GPPGPKGAPGERGSLGPPGPPGL 114
                                                GPPGP G  G  G LG PG PGL
Sbjct: 343 LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL 402

Query: 115 GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQC 174
            G+      G+ G  GP G  GL GPPG +G  G  G  G  G PG PGV  +   D   
Sbjct: 403 KGES-----GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFD--- 454

Query: 175 PSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLR 234
                 G PG PG  G +G TG +G  G  G+DGE+GD G  GP GLPG     GPRGL 
Sbjct: 455 ------GLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGE---SGPRGLL 505

Query: 235 GLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT---P 291
              GP GPPG  GP G RG  G  G  G  G +GE GP G +G  G  G PGP+G     
Sbjct: 506 ---GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPH 562

Query: 292 GVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGER 351
           G  GP G+PG+PG  G +G PG  G++G  G  G  G  GP G  G PG  G KG  G R
Sbjct: 563 GEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIR 622

Query: 352 GRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP---------PGAPGVR 402
           G  G  GE G  G PG  GD G+ G+RGE G  GS G  GP+GP         PG PG+ 
Sbjct: 623 GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 682

Query: 403 GFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLV 462
           G +G+ G  G PG PG QG +G +G  G  GA+G KG +G++G  G  G++G  GP G  
Sbjct: 683 GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 742

Query: 463 GPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK--EA 520
           GP+G +G  G  G  G  GP+G  G +G+PGP GP G  G  G PG  GK G+PG   + 
Sbjct: 743 GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 802

Query: 521 SEQRIRELCG--GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARG 578
            E   +   G  G       Q AA    P+  G  G PGP GPPG  G PG+ G  G +G
Sbjct: 803 GEVGFQGKTGPPGPPGVVGPQGAAGETGPM--GERGHPGPPGPPGEQGLPGTAGKEGTKG 860

Query: 579 PPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGA 637
            PG  G  G+ G  G RG  G+RG  G AG  GL G EG  GP GP G PG       G 
Sbjct: 861 DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 920

Query: 638 P-GEPGPPGDPGLPGAIGAQGTPG 660
           P G PG PG  G PGA G +G PG
Sbjct: 921 PIGPPGRPGPQGPPGAAGEKGVPG 944



 Score =  474 bits (1221), Expect = e-134
 Identities = 285/653 (43%), Positives = 323/653 (49%), Gaps = 74/653 (11%)

Query: 29   GLPGPPGPPGPPGK------PGQDG---IDGEAGPPGLPGPPGPKGA------------P 67
            G PGP GPPGPPGK      PGQ G     G+ GPPG PG  GP+GA            P
Sbjct: 779  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 838

Query: 68   GKPGKPGEAGLPGL---------PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGK 117
            G PG PGE GLPG          PG  G  G+DGP G +G PGERG  G  G PGL G +
Sbjct: 839  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 898

Query: 118  GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG----VLPEGATDLQ 173
            G  GPPG AG  G  G  G  GP GP G PG  GPPG  G  G PG    + P G   +Q
Sbjct: 899  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958

Query: 174  CPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGL 233
             P +  PGP GPPG+ G  G  G  G+ G+ G  G KG+ GPPGP G  G VG  G  G 
Sbjct: 959  GP-VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1017

Query: 234  RGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGV 293
             G PG  GP G  G  G  G  G  G PG  G +G  GP G +G  GD+G  GP G PG 
Sbjct: 1018 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1077

Query: 294  AGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGR 353
             GP+         G NG  G  G  G  G  G PGEKG  G  G PG  G  G KG RG 
Sbjct: 1078 RGPA---------GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE 1128

Query: 354  AGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGD 413
             GE GE+G  GEPG PG  G  G+ G  G+ G  G  G  GPPG  G RG  G KG  G+
Sbjct: 1129 RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGE 1188

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGE 473
             G PG  G  G  G+ GP G  G +G  G  GS+G  G KG  G  G +G  G++G  G 
Sbjct: 1189 DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGP 1248

Query: 474  LGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMI 533
             GP G  GP+G  G+ G  G  G  G  G  G PG  G PG+PG       +R   G   
Sbjct: 1249 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG-------LRGDAGAKG 1301

Query: 534  SEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPG 593
             +    L   +  P   G  G  G  GP G PG  G +G PGA GP G  GP G  G  G
Sbjct: 1302 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAG 1361

Query: 594  PRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD 646
            P      +G KGA G G  GP+G++G QGP              PG PGPPG+
Sbjct: 1362 P------KGAKGATGPG--GPKGEKGVQGP--------------PGHPGPPGE 1392



 Score =  453 bits (1166), Expect = e-127
 Identities = 275/651 (42%), Positives = 319/651 (49%), Gaps = 78/651 (11%)

Query: 25   AQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK------PGEAGL 78
            A   G  G  G PGPPG PG+ G+ G AG  G  G PGP GAPGK G       PGE GL
Sbjct: 826  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 885

Query: 79   PGL---PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
            PG    PG+ G  G  GPPGP G+PGERG+ G  GP  +G  G PGP G  G +G  G  
Sbjct: 886  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP--IGPPGRPGPQGPPGAAGEKGVP 943

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEG------------ATDLQCPSICPPGPP 183
            G +GP GP+G  G+ GP G PGP G PGV  E              T        PPGPP
Sbjct: 944  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1003

Query: 184  GP------PGMPGFKGPTGYKGEQGEVGKDGEKGD---PGPPGPAGLPGSVGLQGPRGLR 234
            GP      PG  G  G  G +G QG  G  G++G     GPPGP GL G  G  G +G  
Sbjct: 1004 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063

Query: 235  GLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVA 294
            G  GP+GPPG  GP G  GP G  G  G  G  G  GP G +G  G+ G PG +G PGV 
Sbjct: 1064 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1123

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRA 354
            GP GE G  G+ GQ G PG  G KG  G +G  G  GP G PG PG  G  G +G+ G  
Sbjct: 1124 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1183

Query: 355  GELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDP 414
            G+ GE G  G+PG P         G  G  G  G LG +GP G+PG  G QG KG+ GDP
Sbjct: 1184 GDRGEDGEPGQPGSP---------GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234

Query: 415  GLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGS---DGLPGDKGELGPSGLVGPKGESGSR 471
            G  G  G  G VG  GP G  GP G +G+ GS    G PG  G+ GP G VGP G  G R
Sbjct: 1235 GAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1294

Query: 472  GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGG 531
            G+ G KG +   G  G+ G+ GPPG  G +G  G+PG  G PG  G+             
Sbjct: 1295 GDAGAKGEK---GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE------------- 1338

Query: 532  MISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGD 591
                        +  P A G IG  GP G PGP GP G+ G  G  GP G +G  G  G 
Sbjct: 1339 ------------MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1386

Query: 592  PGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPG 642
            PGP G                  +G +  Q  + +P        GAPG PG
Sbjct: 1387 PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP------TGGAPGSPG 1431



 Score =  394 bits (1011), Expect = e-109
 Identities = 240/560 (42%), Positives = 283/560 (50%), Gaps = 56/560 (10%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            GE  AA     +G PG PGP GPPG  G+ G+ GE GP    GP G  G  G  G PG A
Sbjct: 911  GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP---IGPTGRDGVQGPVGLPGPA 967

Query: 77   GLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG----LGGKGLPGPPGEAGVSGPP 132
            G PG+ G DG  G  G PG KG  G +G  GPPGPPG    +G  G  G  GE G  GP 
Sbjct: 968  GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1027

Query: 133  GGIGLR---------GPPGPSGLPGLPGPP------------GPPGPPGHPGVL-PEGAT 170
            G  G +         GPPGP GL GLPGP             GPPGPPG  G   P GA 
Sbjct: 1028 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA- 1086

Query: 171  DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP 230
                      GP GPPG  G  GP G KGE GE G  G +G+PG  GP G  G  G  G 
Sbjct: 1087 ---------DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1137

Query: 231  RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT 290
             G  G PGP GP GD GP G  GP G PG PG  G+ G RG +G +G +G+ G PG  G+
Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1197

Query: 291  PGVAGPSGEPGMPGKDGQNGVPGLDGQ------KGEAGRNGAPGEKGPNGLPGLPGRAGS 344
            PG  G +G PG  GK G  G PG +G+      KG+ G  GAPG+ GP G  G  G+ G 
Sbjct: 1198 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1257

Query: 345  KGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGF 404
             G +G  G  G+ G  G +G+ G PG  G P   G  G RG AGA G +G PG  G+ G 
Sbjct: 1258 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPP---GLPGLRGDAGAKGEKGHPGLIGLIGP 1314

Query: 405  QGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGP 464
             G++G  GD GLPGPQG  G  G+ G  GA+GP G     G  GLPG  G  G  G  GP
Sbjct: 1315 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP---GGPPGLPGPAGPKGAKGATGP 1371

Query: 465  KGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVP--GKEASE 522
             G  G +G  GP G  GP G   +Q +P        + V G   +     +P  G   S 
Sbjct: 1372 GGPKGEKGVQGPPGHPGPPG-EVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1430

Query: 523  QRIRELCGGM--ISEQIAQL 540
              + E+ G +  + E+I Q+
Sbjct: 1431 GGLEEIFGSLDSLREEIEQM 1450



 Score =  335 bits (859), Expect = 8e-92
 Identities = 229/585 (39%), Positives = 266/585 (45%), Gaps = 140/585 (23%)

Query: 222 PGSVGLQGPRGLRG--------LPGPL--GPPGDRGPIGFRGPPGIPGAPGKAGDRGERG 271
           P S    GPRGL+G         PG L  GPPG  GP G  GPPGI G PG  GD GERG
Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322

Query: 272 PEGFRGPKGDLGRPGPKGT----------------PGVA------------------GPS 297
           P G  G  G  G PGP GT                P VA                  GP 
Sbjct: 323 PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382

Query: 298 GEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGEL 357
           G  G  G+ G  G PG  G KGE+G  G  G +GP GL G PG+A      G RGRAG  
Sbjct: 383 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKA------GRRGRAGAD 436

Query: 358 GEAGPSGEPGVPGDA---GMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ------- 407
           G  G  G+PGV GD    G+PG  GE GHRG  GA G  GPPG  G RG  G+       
Sbjct: 437 GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 496

Query: 408 --------KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPS 459
                    G  G PG+PGP G+RG  G +GP G+ GP+G+ G  G  G PG +G  GP 
Sbjct: 497 GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 556

Query: 460 GLVGPKGESGSR------------------GELGPKGTQGPNGTSGVQGVPGPPGPLGLQ 501
           G +GP GE G +                  G+ GP GT+G  G SG QG  G PGP G++
Sbjct: 557 GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVK 616

Query: 502 GVPGVPGI------------------------TGKPGVPGK--EASEQRIRELCG----- 530
           GV G+ G+                         G+ GVPG   E   +  +   G     
Sbjct: 617 GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 676

Query: 531 ---GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTG 587
              G++ E+       L  P  PG  GR GP G  G PG PG+ G  GARG  G  GP G
Sbjct: 677 GPPGLMGEK-----GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 731

Query: 588 ELGDPGPRGNQGDRGDKGAAGA----GLDGPEGD------QGPQGPQGVPG----TSKDG 633
           E G  GPRG +G RG  G +GA    G DGP G        GPQGP G PG        G
Sbjct: 732 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 791

Query: 634 QDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678
           +DG PG PG  G+ G  G  G  G PG+       G   G +GE+
Sbjct: 792 KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGET-GPMGER 835


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  521 bits (1343), Expect = e-148
 Identities = 321/752 (42%), Positives = 369/752 (49%), Gaps = 130/752 (17%)

Query: 29   GLPGPPGPPGP------PGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLP 82
            G+PG PG  G       PG PG+ G  G+ G  GLPGPPG  G  G  G+ G  GLPG  
Sbjct: 547  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 606

Query: 83   GVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGPPGEAG------VSGPPGGI 135
            G  GL G  GPPG  G PG RG  GP GP G LG +G PGPPG+ G      + GP G I
Sbjct: 607  GPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI 666

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGP---PGPPGM--- 188
            G  G  GP G PGLPG PG  GPPGHPG   P G    Q PS  P GP   PGP G+   
Sbjct: 667  GPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS-GPQGPLGYPGPRGVKGV 725

Query: 189  ------------------PGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGL------PGS 224
                              PGFKG  G KG++GEVG  G +G+ GP GP G       PG 
Sbjct: 726  DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 785

Query: 225  VGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPG---------KAGDRGERGPEGF 275
             GL G +G  G+PG  G PG +GP G  G PG PGA G         K+G RGERGP G 
Sbjct: 786  PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGP 845

Query: 276  RG------------------------PKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
            RG                        P G+ G PGP+G  G  GP G PG PGKDG  G 
Sbjct: 846  RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGH 905

Query: 312  PG------------------------LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE 347
            PG                          G+ G  G  G PG  GP G  GLPG AG +G 
Sbjct: 906  PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965

Query: 348  KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ 407
            KG+ G  G  G+ GP+G  G PG+ G+PG  G  G +G+ G  GP GP G+PG RG  G 
Sbjct: 966  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025

Query: 408  KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE 467
             G +G PG PGPQG  G  G++G  G  GP G     G DG+ G  G  GP+G  G  GE
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP---TGRDGVQGPVGLPGPAGPPGVAGE 1082

Query: 468  SGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SE 522
             G +GE+G  G +G  G  G  G PGPPGP+G  G PG  G  G+PG  G +       +
Sbjct: 1083 DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD 1142

Query: 523  QRIRELCG--GMISEQIAQLAAHLRKPLA-PGSIGRPGPAGPPGPPGPPGSIGHPGARGP 579
            +  R   G  G I  Q       L  P    G  G  GP GPPGPPGP G  G  GA GP
Sbjct: 1143 EGTRGFNGPPGPIGLQ------GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1196

Query: 580  PGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPG---------- 628
             G  G  G LG PG +G  G+ G  G  G  G+ GP G++G +G  G PG          
Sbjct: 1197 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1256

Query: 629  TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            T  DG  G PG  G PGDPG PG  G +G  G
Sbjct: 1257 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG 1288



 Score =  504 bits (1298), Expect = e-142
 Identities = 310/737 (42%), Positives = 353/737 (47%), Gaps = 117/737 (15%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            GLPG PG  GPPG PG++G  G  G  G  GP GP G PG  G  G  G+ GL G  G  
Sbjct: 679  GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK 738

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGGKGLP-GPPGEAGVSGPPGGIGLRGPPGPSGLP 147
            G DG PG KG  G +G  G  G PG  G+  P GP G  G +G PG  GL G  G  G+P
Sbjct: 739  GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVP 798

Query: 148  GLPGPPGPPGP------PGHPGVLPE-GATDLQCPSICPPGPPGPPGMPGFKGPTGYKGE 200
            GLPG PG  GP      PG PG   E GA  L        G  GP G  G  GP G +G 
Sbjct: 799  GLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS-------GKSGPRGERGPTGPRGQRGP 851

Query: 201  QGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG------------DRGP 248
            +G  GK G KG  G  GP G PG  GL GP+G  G PGP GPPG             RG 
Sbjct: 852  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 911

Query: 249  IGFRG---PPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGE------ 299
            +GF+G   PPG PG  G  G  GE GP G RG  G  G PG +G PG AG  G       
Sbjct: 912  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 971

Query: 300  PGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG- 358
            PG PGKDG  G+ G  G++G  G  G PG KG  G  G PG AGS GE+G  G  G +G 
Sbjct: 972  PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 1031

Query: 359  --EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGP---QGPPGAPGVRGFQGQKGSMGD 413
                GP G PG  G+ G+PGE+G  G  G  G  GP    GP G PGV G  G KG +GD
Sbjct: 1032 PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1091

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE------------------ 455
            PG  G +G +G+ G  GP G  GP G  G AG+DG PG +G                   
Sbjct: 1092 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1151

Query: 456  ---LGPSGLVGPKGESGSRGELGP---------KGTQGPNGTSGVQGVPG------PPGP 497
               +G  GL GP GE G  G++GP         +G  GPNG  G QG PG      PPG 
Sbjct: 1152 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1211

Query: 498  LGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPG 557
             G  G  G PGI G+PGV G         E                  +P  PG  G  G
Sbjct: 1212 KGEPGESGSPGIQGEPGVKGPRGERGEKGES----------------GQPGEPGPPGPKG 1255

Query: 558  PAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEG 616
            P G  GP G PG +G PG  GPPG  GP G+ G  G RG  G+ G  G+ G  G +GP G
Sbjct: 1256 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1315

Query: 617  DQGPQGPQGVPG----------------------TSKDGQDGAPGEPGPPGDPGLPGAIG 654
              G +GP G PG                      T   G  G  G+PGP G  GLPG++G
Sbjct: 1316 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1375

Query: 655  AQGTPGICDTSACQGAV 671
             QG PG    +   G V
Sbjct: 1376 QQGRPGATGQAGPPGPV 1392



 Score =  504 bits (1297), Expect = e-142
 Identities = 300/673 (44%), Positives = 337/673 (50%), Gaps = 76/673 (11%)

Query: 27   RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDG 86
            R G  G PGPPG  G+ G+ G+ G  G PG  GP G  G PG PG  GE G  GL G  G
Sbjct: 776  RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSG 835

Query: 87   LTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSG 145
              G  GP GP+G  G RG+ G  G  G  GG G  GPPGE G+ GP G  G  GP GP  
Sbjct: 836  PRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-- 893

Query: 146  LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205
                PGPPG  G PGHPG    G    Q       G  GPPG PG  GP G  GE G +G
Sbjct: 894  ----PGPPGKDGLPGHPG--QRGEVGFQ-------GKTGPPGPPGVVGPQGAAGETGPMG 940

Query: 206  KDGEKGDPGPPGPAGLPGSVGLQ---------------GPRGLRGLPGPLGPPGDRGPIG 250
            + G  G PGPPG  GLPG+ G +               GP GLRG PG  G PG  G  G
Sbjct: 941  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPG 1000

Query: 251  FRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMP---GKDG 307
             +G  G  G PG AG  GERG  G  GP G  GRPGP+G PG AG  G PG     G  G
Sbjct: 1001 LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 1060

Query: 308  QNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPG 367
            ++GV G  G  G AG  G  GE G  G  G PG+ G+KG KGE G  G  G  GP G+PG
Sbjct: 1061 RDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1120

Query: 368  VPGDAGMPGERGEAGH------RGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQG 421
              G  G PG RG  GH       G+ G  GP GP G  G+ G  G+KG  GD G  GP G
Sbjct: 1121 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1180

Query: 422  LRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQG 481
              G  G  GP GA GP+G  G  G+ G PG+KGE G SG  G +GE G +G  G +G +G
Sbjct: 1181 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1240

Query: 482  PNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLA 541
             +G  G  G PGP GP G  G  G PG  G PG PG            GG   +      
Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE--------GGPRGQD----- 1287

Query: 542  AHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDR 601
                     G+ G  G  G PG PG PG  G  G  GP G RGP G  G  G +G +G +
Sbjct: 1288 ---------GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAK 1338

Query: 602  GDKGAAGA-------GLDGPEGDQGPQGPQGVPGT-------SKDGQDGAPGEPGPPGDP 647
            GD GA GA       G  GP G  GP G +G+PG+          GQ G PG  GPPG P
Sbjct: 1339 GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1398

Query: 648  GLPGAIGAQGTPG 660
            GL G  GA+G  G
Sbjct: 1399 GLRGDAGAKGEKG 1411



 Score =  500 bits (1287), Expect = e-141
 Identities = 310/729 (42%), Positives = 347/729 (47%), Gaps = 95/729 (13%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            G++        VG+PG  G  GP G  G+ G  G+ GPPGL G  G  G PG PG PG  
Sbjct: 748  GDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 807

Query: 77   G------LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPG---PPGLGGK-GLPGPPGEA 126
            G       PG PG  G  G  G  G  G  GERG  GP G   P G  GK G  G  G  
Sbjct: 808  GPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 867

Query: 127  GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGP---PGHPGVLPEGATDLQCPSICPPGPP 183
            G  GPPG  GL GP GP+G PG  GPPGPPG    PGHPG    G    Q       G  
Sbjct: 868  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG--QRGEVGFQ-------GKT 918

Query: 184  GPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQG-------------- 229
            GPPG PG  GP G  GE G +G+ G  G PGPPG  GLPG+ G +G              
Sbjct: 919  GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 978

Query: 230  -PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPK 288
             P GLRG PG  G PG  G  G +G  G  G PG AG  GERG  G  GP G  GRPGP+
Sbjct: 979  GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 1038

Query: 289  GTPGVAGPSGEPGMPGK---DGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G PG AG  G PG  G     G++GV G  G  G AG  G  GE G  G  G PG+ G+K
Sbjct: 1039 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1098

Query: 346  GEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH------RGSAGALGPQGPPGAP 399
            G KGE G  G  G  GP G+PG  G  G PG RG  GH       G+ G  GP GP G  
Sbjct: 1099 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1158

Query: 400  GVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPS 459
            G+ G  G+KG  GD G  GP G  G  G  GP GA GP+G  G  G+ G PG+KGE G S
Sbjct: 1159 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1218

Query: 460  GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE 519
            G  G +GE G +G  G +G +G +G  G  G PGP GP G  G  G PG  G PG PG  
Sbjct: 1219 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP 1278

Query: 520  ASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGP------------ 567
                      GG   +  A+      +   PG  G PGP G  GPPGP            
Sbjct: 1279 GE--------GGPRGQDGAK--GDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGS 1328

Query: 568  ------------PGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPE 615
                        PG+IG PG  GP G  GP G+ G  G RG  G  G +G  GA   G  
Sbjct: 1329 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGA--TGQA 1386

Query: 616  GDQGPQGPQGVPGTSKD-------------GQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662
            G  GP GP G+PG   D             G  G PGE G  GD GLPG  G+ G  G  
Sbjct: 1387 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1446

Query: 663  DTSACQGAV 671
                  G +
Sbjct: 1447 GIPGASGPI 1455



 Score =  499 bits (1284), Expect = e-141
 Identities = 310/728 (42%), Positives = 356/728 (48%), Gaps = 100/728 (13%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA---PGKPGKPGEAGLPGLPGVD 85
            G  GP G PGPPG  G+ G  G  G PG PG  GPKG+   PG PG  GE G  GL G  
Sbjct: 775  GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKS 834

Query: 86   GLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGL---RGPP 141
            G  G  GP GP+G  G RG+ G  G  G  GG G  GPPGE G+ GP G  G    +GPP
Sbjct: 835  GPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP 894

Query: 142  GPSGLPGLPGPPGP---------PGPPGHPGVL-PEGATDLQCPS-----ICPPGPPG-- 184
            GP G  GLPG PG           GPPG PGV+ P+GA     P        PPGPPG  
Sbjct: 895  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 954

Query: 185  ----------------PPGMPGFKGPTGYKGEQGEVGKDGEKGDPG---------PPGPA 219
                            PPG PG  GP G +G  GE G  G  G PG         PPGPA
Sbjct: 955  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 1014

Query: 220  GLPG---SVGLQGPRGLRGLPGPLGPPGD---------------------RGPIGFRGPP 255
            G PG   + G  GP G  G PGP GPPG                      +GP+G  GP 
Sbjct: 1015 GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA 1074

Query: 256  GIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLD 315
            G PG  G+ GD+GE G  G +G KG+ G  GP G PG  GP G+PG  G DG+ G  G  
Sbjct: 1075 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1134

Query: 316  GQ---KGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGE------------RGRAGELGEA 360
            G    KG+ G  G  G  GP GL GLPG +G KGE G+            RG AG  G  
Sbjct: 1135 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGAD 1194

Query: 361  GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420
            GP G PG  G+ G PGE+GE G  GS G    QG PG  G RG +G+KG  G PG PGP 
Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGI---QGEPGVKGPRGERGEKGESGQPGEPGPP 1251

Query: 421  GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480
            G +G  GD GP G  GP G  G  G  G  G +G+ G  G  G  GE G  G  GP G  
Sbjct: 1252 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1311

Query: 481  GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL 540
            GP G  G +G  G PG  G QG  G  G  G  G PGK           G    + +  L
Sbjct: 1312 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP-AGKPGPDGLRGL 1370

Query: 541  AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD 600
               + +   PG+ G+ GP GP GPPG PG  G  GA+G  G+ G  G +G PG +G +GD
Sbjct: 1371 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1430

Query: 601  RGDKGAAGA-------GLDGPEGDQGPQGPQGVPGTS-KDGQDGAPGEPGPPGDPGLPGA 652
            RG  G  G+       G+ G  G  GP GP G+PG +   G  GA G  GP G+ G+ G 
Sbjct: 1431 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1490

Query: 653  IGAQGTPG 660
             G  G PG
Sbjct: 1491 PGHPGPPG 1498



 Score =  487 bits (1254), Expect = e-137
 Identities = 301/702 (42%), Positives = 348/702 (49%), Gaps = 85/702 (12%)

Query: 21   AAAGAQRVGLPGPPGPPGP-------PGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKP 73
            AAA   R GL G  G P          G PG +G  G  GPPG+ G PGP G PG+ G P
Sbjct: 373  AAAHGPR-GLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 431

Query: 74   GEAGLPGLPGVDGLTGRD-------------------------------------GPPGP 96
            G AGLPG  G  G  G                                       GPPGP
Sbjct: 432  GRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGP 491

Query: 97   KGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPP 156
             G  G  G LG PG PGL G+      G+ G  GP G  GL GPPG +G  G  G  G  
Sbjct: 492  MGYTGRPGPLGQPGSPGLKGES-----GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 546

Query: 157  GPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPP 216
            G PG PGV  +   D         G PG PG  G +G TG +G  G  G+DGE+GD G  
Sbjct: 547  GMPGDPGVKGDRGFD---------GLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 597

Query: 217  GPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFR 276
            GP GLPG     GPRGL    GP GPPG  GP G RG  G  G  G  G +GE GP G +
Sbjct: 598  GPRGLPGE---SGPRGLL---GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ 651

Query: 277  GPKGDLGRPGPKGT---PGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPN 333
            G  G  G PGP+G     G  GP G+PG+PG  G +G PG  G++G  G  G  G  GP 
Sbjct: 652  GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 711

Query: 334  GLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQ 393
            G  G PG  G KG  G RG  G  GE G  G PG  GD G+ G+RGE G  GS G  GP+
Sbjct: 712  GPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 771

Query: 394  GP---------PGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIA 444
            GP         PG PG+ G +G+ G  G PG PG QG +G +G  G  GA+G KG +G++
Sbjct: 772  GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 831

Query: 445  GSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVP 504
            G  G  G++G  GP G  GP+G +G  G  G  G  GP+G  G +G+PGP GP G  G  
Sbjct: 832  GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 891

Query: 505  GVPGITGKPGVPGK--EASEQRIRELCG--GMISEQIAQLAAHLRKPLAPGSIGRPGPAG 560
            G PG  GK G+PG   +  E   +   G  G       Q AA    P+  G  G PGP G
Sbjct: 892  GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPM--GERGHPGPPG 949

Query: 561  PPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQG 619
            PPG  G PG+ G  G +G PG  G  G+ G  G RG  G+RG  G AG  GL G EG  G
Sbjct: 950  PPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 1009

Query: 620  PQGPQGVPGTSKDGQDGAP-GEPGPPGDPGLPGAIGAQGTPG 660
            P GP G PG       G P G PG PG  G PGA G +G PG
Sbjct: 1010 PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 1051



 Score =  474 bits (1221), Expect = e-134
 Identities = 285/653 (43%), Positives = 323/653 (49%), Gaps = 74/653 (11%)

Query: 29   GLPGPPGPPGPPGK------PGQDG---IDGEAGPPGLPGPPGPKGA------------P 67
            G PGP GPPGPPGK      PGQ G     G+ GPPG PG  GP+GA            P
Sbjct: 886  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 945

Query: 68   GKPGKPGEAGLPGL---------PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGK 117
            G PG PGE GLPG          PG  G  G+DGP G +G PGERG  G  G PGL G +
Sbjct: 946  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 1005

Query: 118  GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG----VLPEGATDLQ 173
            G  GPPG AG  G  G  G  GP GP G PG  GPPG  G  G PG    + P G   +Q
Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 1065

Query: 174  CPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGL 233
             P +  PGP GPPG+ G  G  G  G+ G+ G  G KG+ GPPGP G  G VG  G  G 
Sbjct: 1066 GP-VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1124

Query: 234  RGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGV 293
             G PG  GP G  G  G  G  G  G PG  G +G  GP G +G  GD+G  GP G PG 
Sbjct: 1125 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1184

Query: 294  AGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGR 353
             GP+         G NG  G  G  G  G  G PGEKG  G  G PG  G  G KG RG 
Sbjct: 1185 RGPA---------GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE 1235

Query: 354  AGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGD 413
             GE GE+G  GEPG PG  G  G+ G  G+ G  G  G  GPPG  G RG  G KG  G+
Sbjct: 1236 RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGE 1295

Query: 414  PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGE 473
             G PG  G  G  G+ GP G  G +G  G  GS+G  G KG  G  G +G  G++G  G 
Sbjct: 1296 DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGP 1355

Query: 474  LGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMI 533
             GP G  GP+G  G+ G  G  G  G  G  G PG  G PG+PG       +R   G   
Sbjct: 1356 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG-------LRGDAGAKG 1408

Query: 534  SEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPG 593
             +    L   +  P   G  G  G  GP G PG  G +G PGA GP G  GP G  G  G
Sbjct: 1409 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAG 1468

Query: 594  PRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD 646
            P      +G KGA G G  GP+G++G QGP              PG PGPPG+
Sbjct: 1469 P------KGAKGATGPG--GPKGEKGVQGP--------------PGHPGPPGE 1499



 Score =  453 bits (1166), Expect = e-127
 Identities = 275/651 (42%), Positives = 319/651 (49%), Gaps = 78/651 (11%)

Query: 25   AQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK------PGEAGL 78
            A   G  G  G PGPPG PG+ G+ G AG  G  G PGP GAPGK G       PGE GL
Sbjct: 933  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 992

Query: 79   PGL---PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
            PG    PG+ G  G  GPPGP G+PGERG+ G  GP  +G  G PGP G  G +G  G  
Sbjct: 993  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP--IGPPGRPGPQGPPGAAGEKGVP 1050

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEG------------ATDLQCPSICPPGPP 183
            G +GP GP+G  G+ GP G PGP G PGV  E              T        PPGPP
Sbjct: 1051 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1110

Query: 184  GP------PGMPGFKGPTGYKGEQGEVGKDGEKGD---PGPPGPAGLPGSVGLQGPRGLR 234
            GP      PG  G  G  G +G QG  G  G++G     GPPGP GL G  G  G +G  
Sbjct: 1111 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1170

Query: 235  GLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVA 294
            G  GP+GPPG  GP G  GP G  G  G  G  G  GP G +G  G+ G PG +G PGV 
Sbjct: 1171 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1230

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRA 354
            GP GE G  G+ GQ G PG  G KG  G +G  G  GP G PG PG  G  G +G+ G  
Sbjct: 1231 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1290

Query: 355  GELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDP 414
            G+ GE G  G+PG P         G  G  G  G LG +GP G+PG  G QG KG+ GDP
Sbjct: 1291 GDRGEDGEPGQPGSP---------GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1341

Query: 415  GLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGS---DGLPGDKGELGPSGLVGPKGESGSR 471
            G  G  G  G VG  GP G  GP G +G+ GS    G PG  G+ GP G VGP G  G R
Sbjct: 1342 GAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1401

Query: 472  GELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGG 531
            G+ G KG +   G  G+ G+ GPPG  G +G  G+PG  G PG  G+             
Sbjct: 1402 GDAGAKGEK---GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGE------------- 1445

Query: 532  MISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGD 591
                        +  P A G IG  GP G PGP GP G+ G  G  GP G +G  G  G 
Sbjct: 1446 ------------MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1493

Query: 592  PGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPG 642
            PGP G                  +G +  Q  + +P        GAPG PG
Sbjct: 1494 PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP------TGGAPGSPG 1538



 Score =  394 bits (1011), Expect = e-109
 Identities = 240/560 (42%), Positives = 283/560 (50%), Gaps = 56/560 (10%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            GE  AA     +G PG PGP GPPG  G+ G+ GE GP    GP G  G  G  G PG A
Sbjct: 1018 GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP---IGPTGRDGVQGPVGLPGPA 1074

Query: 77   GLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG----LGGKGLPGPPGEAGVSGPP 132
            G PG+ G DG  G  G PG KG  G +G  GPPGPPG    +G  G  G  GE G  GP 
Sbjct: 1075 GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1134

Query: 133  GGIGLR---------GPPGPSGLPGLPGPP------------GPPGPPGHPGVL-PEGAT 170
            G  G +         GPPGP GL GLPGP             GPPGPPG  G   P GA 
Sbjct: 1135 GHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA- 1193

Query: 171  DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGP 230
                      GP GPPG  G  GP G KGE GE G  G +G+PG  GP G  G  G  G 
Sbjct: 1194 ---------DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1244

Query: 231  RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT 290
             G  G PGP GP GD GP G  GP G PG PG  G+ G RG +G +G +G+ G PG  G+
Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1304

Query: 291  PGVAGPSGEPGMPGKDGQNGVPGLDGQ------KGEAGRNGAPGEKGPNGLPGLPGRAGS 344
            PG  G +G PG  GK G  G PG +G+      KG+ G  GAPG+ GP G  G  G+ G 
Sbjct: 1305 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1364

Query: 345  KGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGF 404
             G +G  G  G+ G  G +G+ G PG  G P   G  G RG AGA G +G PG  G+ G 
Sbjct: 1365 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPP---GLPGLRGDAGAKGEKGHPGLIGLIGP 1421

Query: 405  QGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGP 464
             G++G  GD GLPGPQG  G  G+ G  GA+GP G     G  GLPG  G  G  G  GP
Sbjct: 1422 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP---GGPPGLPGPAGPKGAKGATGP 1478

Query: 465  KGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVP--GKEASE 522
             G  G +G  GP G  GP G   +Q +P        + V G   +     +P  G   S 
Sbjct: 1479 GGPKGEKGVQGPPGHPGPPG-EVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1537

Query: 523  QRIRELCGGM--ISEQIAQL 540
              + E+ G +  + E+I Q+
Sbjct: 1538 GGLEEIFGSLDSLREEIEQM 1557



 Score =  213 bits (542), Expect = 5e-55
 Identities = 154/431 (35%), Positives = 186/431 (43%), Gaps = 74/431 (17%)

Query: 262 GKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEA 321
           G+ G     GP  +    GD  R   +  P ++  +   G       +G  GL G+KGE 
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAA----HGPRGLKGEKGEP 388

Query: 322 GR-------NGAPGEKGPNGL---PGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGD 371
                     G PG +GP GL   PG+ G  G  G+ GERG  G  G  G  G PG PG 
Sbjct: 389 AVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGT 448

Query: 372 AGM--------PGERGE--AGHRGSAGALGPQGP---PGAPGVRGFQGQKGSMGDPGLPG 418
           + M         G++G   A     A A+  Q      G PG  G+ G+ G +G PG PG
Sbjct: 449 SLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 508

Query: 419 PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG 478
            +G  GD+G +GP G  G  G  G AG  G  G  G  G  G  G KG+ G  G  G  G
Sbjct: 509 LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 568

Query: 479 TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538
            +G  G +G QG+PGPPG  G +G  G  G  G PG  G                     
Sbjct: 569 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR------------------- 609

Query: 539 QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQ 598
                          G  GP GPPG PGPPG  G  G +GP G  GP GE G PG +G  
Sbjct: 610 ---------------GLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 654

Query: 599 GDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGT 658
           G +G  G  GA   GP G++GPQG  G+PG            PG  G PG PG  G  GT
Sbjct: 655 GTQGLPGPQGA--IGPHGEKGPQGKPGLPGM-----------PGSDGPPGHPGKEGPPGT 701

Query: 659 PGICDTSACQG 669
            G    S  QG
Sbjct: 702 KGNQGPSGPQG 712



 Score =  167 bits (422), Expect = 4e-41
 Identities = 133/359 (37%), Positives = 150/359 (41%), Gaps = 84/359 (23%)

Query: 359 EAGP--SGEPGVPGDAGMPGERGEAGHRGSAGALGP----QGPPGAPGVRGFQGQKGSMG 412
           E GP  S E    G A   G RG  G +G    L P    +GPPG       +G  G +G
Sbjct: 359 ELGPALSAETAHSG-AAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP------EGPAGLIG 411

Query: 413 DPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDG----LP-------GDKGELGPS-- 459
            PG+ G  G  GD G+RGP G AG  G  G  G  G    LP       GDKG +  +  
Sbjct: 412 PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQE 471

Query: 460 ------------GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVP 507
                        L GP G  G  G  GP G  G  G  G  G  GP GP G QG+ G P
Sbjct: 472 AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP 531

Query: 508 GITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGP 567
           G  G+ G  G                               A G+ G PG    PG  G 
Sbjct: 532 GKAGRRGRAG-------------------------------ADGARGMPGD---PGVKGD 557

Query: 568 PGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA----GLDGPEGDQGPQGP 623
            G  G PG  G  G+RG TG  G PGP G  G+RGD G  G     G  GP G  GP+GP
Sbjct: 558 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 617

Query: 624 QGVPGT----SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678
            G+PG       DG  G  G  GP G+PG PG    QGTPG       QGA+ G  GEK
Sbjct: 618 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ---QGTPGTQGLPGPQGAI-GPHGEK 672


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  519 bits (1337), Expect = e-147
 Identities = 316/737 (42%), Positives = 363/737 (49%), Gaps = 110/737 (14%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            G+PG  G  GP G+PG  GI G  GPPG  G  GP+G PG  G PG  G  G PG  G  
Sbjct: 471  GVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFP 530

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147
            G DG PGPKGA GERG +G  GP G  G  G PG PG  G  G  G  G++GP G  G  
Sbjct: 531  GSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL 590

Query: 148  GLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKD 207
            G PG  G PGPPG  G+  +  + +  P   P G  G PG PG  G  G  G++G  GKD
Sbjct: 591  GAPGEDGRPGPPGSIGIRGQPGS-MGLPG--PKGSSGDPGKPGEAGNAGVPGQRGAPGKD 647

Query: 208  GEKGDPGPPGPAGLPGSVGLQGP---RGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA 264
            GE G  GP GP GL G  G QGP    G +GLPGP GPPG+ G  G +G PG PGA G  
Sbjct: 648  GEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPL 707

Query: 265  GDRGERGPEGFRG------------------PKGDLGRPGPKGTPGVAGPSGEPGMPGK- 305
            G RGERG  G RG                  P G  G PGP GTPG  GP G  GMPG+ 
Sbjct: 708  GPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGER 767

Query: 306  --------------------------DGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLP 339
                                      DG  G+PG  G  G AG  G  GE GP GL G P
Sbjct: 768  GIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPP 827

Query: 340  GRAGSKGEKGERGRAGELGEAGPSG---EPGVPGDAGMPGERGEAGH---RGSAGALGPQ 393
            G  G+ G +GE G  G +G AGP G   +PGV G+ G PG++G+AG    +G AG+ GP 
Sbjct: 828  GSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPH 887

Query: 394  GPPGAPGVRGFQGQK---------------------------GSMGDPGLPGPQGLRGD- 425
            GP G PG++G +G +                           G +G+PG  GP GLRGD 
Sbjct: 888  GPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDP 947

Query: 426  -----VGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPS---------GLVGPKGESGSR 471
                 VGDRGP G  G  GD+G  G DG PG  G  GP+         G+ G +GE G  
Sbjct: 948  GSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMP 1007

Query: 472  GELGPKGTQ---GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIREL 528
            G  GP GT    GP G +G +G PGP GP G  G  G PG  G  G  G    +  + E 
Sbjct: 1008 GLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGER 1067

Query: 529  CGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGE 588
             G       A L      P  PG +G PG AG  G PG  G IG PG  G  G  GP G 
Sbjct: 1068 -GDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGP 1126

Query: 589  LGDPGPRGNQGDRGDKGAAG----AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPP 644
             GD G  G++GDRG KG  G     GL GP G  G QG  G+PG    G  G PG  GP 
Sbjct: 1127 RGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPF--GPRGPPGPVGPS 1184

Query: 645  GDPGLPGAIGAQGTPGI 661
            G  G PG +G  G PG+
Sbjct: 1185 GKEGNPGPLGPIGPPGV 1201



 Score =  519 bits (1337), Expect = e-147
 Identities = 318/726 (43%), Positives = 363/726 (50%), Gaps = 82/726 (11%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            G PG  G PG  G PG  G  GE GP G  GP G +G PG+PG+PG  G  GL G  G+ 
Sbjct: 522  GAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQ 581

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGGK----GLPGPPGEAGVSGPPGGIGLRGPPGPS 144
            G +G  GP GAPGE G  GPPG  G+ G+    GLPGP G +G  G PG  G  G PG  
Sbjct: 582  GPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQR 641

Query: 145  GLPGLPGPPGPPGPPGHPGVL-------PEGATDLQ-CPSICPPGPPGPPGMPGFKGPTG 196
            G PG  G  GP GP G PG+        P G T  Q  P   PPGPPG  G PG +G  G
Sbjct: 642  GAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPG--PPGPPGEGGKPGDQGVPG 699

Query: 197  YKGEQGEVGKDGEKGDPGP---PGPAGLPGSVGL---QGPRGLRGLPGPLGPPGDRGPIG 250
              G  G +G  GE+G+PG    PG  GLPG  G+    GP G +G PGP G PGD GP G
Sbjct: 700  DPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPG 759

Query: 251  FRGPPG---IPGAPGKAGDRG---ERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPG 304
             +G PG   I G PG  GDRG   E+G EG  G  G  G PGP G PG AGP+GE G PG
Sbjct: 760  LQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPG 819

Query: 305  KDGQNGVPGLDGQKGEAGRNGAPGE------KGPNGLPGLPGRAGSKGEKGE------RG 352
              G  G PG  G  G  G NG  G       +GP+G PG+ G  G  G+KG+      +G
Sbjct: 820  PRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQG 879

Query: 353  RAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMG 412
             AG  G  GP+G PG+ G  G  G  G  G  GSAG +GP GP GAPG  G  G+ G  G
Sbjct: 880  LAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEG 939

Query: 413  DPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG---------LVG 463
             PGL G  G  G VGDRGP G  G  GD+G  G DG PG  G  GP+G         + G
Sbjct: 940  PPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPG 999

Query: 464  PKGESGSRGELGPKGTQG---PNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA 520
             +GE G  G  GP GT G   P G +G +G PGP GP G  G  G PG  G  G  G   
Sbjct: 1000 QRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPG 1059

Query: 521  SEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPP 580
             +  + E  G       A L      P  PG +G PG AG  G PG  G IG PG  G  
Sbjct: 1060 RDGAVGER-GDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKR 1118

Query: 581  GYRGPTGELGDPGPRGNQGDRGDKGAAG----AGLDGPEGDQGPQGPQGVPG-------- 628
            G  GP G  GD G  G++GDRG KG  G     GL GP G  G QG  G+PG        
Sbjct: 1119 GLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPP 1178

Query: 629  --TSKDGQDGAPG---------------EPGPPGDPGLPGAIGAQGTPGICDTSACQGAV 671
                  G++G PG               E GP G PG PG  G  G PG    +A  G +
Sbjct: 1179 GPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG--HLTAALGDI 1236

Query: 672  LGGVGE 677
            +G   E
Sbjct: 1237 MGHYDE 1242



 Score =  516 bits (1328), Expect = e-146
 Identities = 305/695 (43%), Positives = 359/695 (51%), Gaps = 86/695 (12%)

Query: 28  VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPG------------- 74
           +G  GP GPPG PG+ G+ G +G  G  G  G PG +G PG PG PG             
Sbjct: 251 IGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGP 310

Query: 75  --EAGLPGLPGVDGLTG---RDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGV 128
             E G PG  G  G TG     GP GP+G PGERG LGP G PG  G  G+PG PG  G 
Sbjct: 311 KGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGP 370

Query: 129 ------SGPPGGIGLRGPPGPSGLPGLPGPPG------PPGPPGHPGVLPEGATDLQCPS 176
                 SG PG  G++G  GP+G  G  GP G      PPGP G PG+     TD    +
Sbjct: 371 LGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGA 430

Query: 177 ICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGL 236
             P G PG  G PG  GP G  G QG  G  G +G PG PG  G  G  G +G  G  G+
Sbjct: 431 KGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGI 490

Query: 237 PGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGE------------RGPEGFRGPKGDLGR 284
            GP+GPPG+ G  G RG PG  G PG  G+RG              GP+G +G +G +G 
Sbjct: 491 QGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGS 550

Query: 285 PGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGS 344
            GPKG+ G  G  GEPG+PG  G  G PG+ G +G+ G  GAPGE   +G PG PG  G 
Sbjct: 551 SGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGE---DGRPGPPGSIGI 607

Query: 345 KGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGF 404
           +G+ G  G  G  G +G  G+PG  G+AG+PG+RG  G  G  G  GP GPPG  G RG 
Sbjct: 608 RGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGE 667

Query: 405 QGQKGSMGDPGLPGPQGLRGD---VGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGL 461
           QG  G  G  GLPGP G  G+    GD+G  G  G  G  G  G  G PG++GE G +GL
Sbjct: 668 QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGL 727

Query: 462 VGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEAS 521
            G KG +G  G  GPKG+ GP+GT      PG  GP GLQG+PG  GI G PG  G    
Sbjct: 728 PGEKGMAGGHGPDGPKGSPGPSGT------PGDTGPPGLQGMPGERGIAGTPGPKGDR-- 779

Query: 522 EQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP---PGPPGPPGSIGHPGARG 578
                   GG+  +     A +      PG +G PGPAGP    G PGP G +G PG+RG
Sbjct: 780 --------GGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831

Query: 579 PPGYR---GPTGELGDPGPRGNQGDRGDKGAAG-------AGLDGPE---GDQGPQGPQG 625
            PG R   GPTG +G  GP+G  G  G KG  G       AG  GP+   G  GP GP G
Sbjct: 832 NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNG 891

Query: 626 VPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
           VPG       G  G  GPPG  G PG+ G  G PG
Sbjct: 892 VPGLK-----GGRGTQGPPGATGFPGSAGRVGPPG 921



 Score =  516 bits (1328), Expect = e-146
 Identities = 321/745 (43%), Positives = 369/745 (49%), Gaps = 128/745 (17%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK---- 72
            GE+ A       G  GP G  GP G  G  G  G  GP G PG  G  G PGKPG     
Sbjct: 312  GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371

Query: 73   --PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSG 130
              PG +G PG PG+ G  G  G  GP+G  G+RG  GPPGP      G PG PG  G  G
Sbjct: 372  GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP-----VGSPGLPGAIGTDG 426

Query: 131  PPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPG 190
             PG  G  G PG SG PG  GPPG PGP G  G  P+G            G PG PG+PG
Sbjct: 427  TPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTG--PQGIR----------GQPGDPGVPG 474

Query: 191  FKGPTGYKGE------------QGEVGKDGEKGDP---GPPGPAGLPGSVGLQGPRGLRG 235
            FKG  G KGE             GE GK G +GDP   GPPGP G  G+ G +G  G  G
Sbjct: 475  FKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDG 534

Query: 236  LPGPLGPPGDRGPIGFRGP------------PGIPGAPGKAGDRGERGPEGFRGP---KG 280
            LPGP G  G+RGP+G  GP            PG+PGA G  G+ G +GPEG  GP    G
Sbjct: 535  LPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPG 594

Query: 281  DLGRPGPKGT------------PGVAGPSGEPGMPGK------DGQNGVPGLDGQ----- 317
            + GRPGP G+            PG  G SG+PG PG+       GQ G PG DG+     
Sbjct: 595  EDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSG 654

Query: 318  -------KGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGE---LGEAGPSGEPG 367
                    GE G  G PG  G  GLPG PG  G  G+ G++G  G+   +G  GP GE G
Sbjct: 655  PVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERG 714

Query: 368  VPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVG 427
             PG+ G PG  G  G +G AG  GP GP G+PG  G  G  G  G  G+PG +G+ G  G
Sbjct: 715  NPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPG 774

Query: 428  DRGPGGAAGPKGDQGIAGSD---GLP------------GDKGELGPSGLVGP---KGESG 469
             +G  G  G KG +G AG+D   GLP            G+KGE GP GLVGP   +G  G
Sbjct: 775  PKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPG 834

Query: 470  SRGELGPKGT------QGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQ 523
            SRGE GP G       QGP+G  GV+G PG PG  G  G PG  G+ G PG  G      
Sbjct: 835  SRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNG--- 891

Query: 524  RIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYR 583
             +  L GG  ++              PGS GR GP GP G PGP G +G PG  GPPG R
Sbjct: 892  -VPGLKGGRGTQGPPGATGF------PGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLR 944

Query: 584  GPT---GELGDPGPRGNQGDRGDKGAAG----AGLDGPEGDQGPQGPQGVPG-TSKDGQD 635
            G     G +GD GP G  G  GDKG  G     G DGP G  G  G +G+ G   + G+ 
Sbjct: 945  GDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGER 1004

Query: 636  GAPGEPGPPGDPGLPGAIGAQGTPG 660
            G PG PGP G PG  G  GA G  G
Sbjct: 1005 GMPGLPGPAGTPGKVGPTGATGDKG 1029



 Score =  514 bits (1325), Expect = e-146
 Identities = 306/695 (44%), Positives = 353/695 (50%), Gaps = 80/695 (11%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
           G+ G PGP GPPG  G     GE GP G PGP GP+G  G+PG PG+ G PG PG     
Sbjct: 126 GIRGRPGPAGPPGSQGP---RGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHP 182

Query: 89  GRDGPPGPKGA------------------PGERGSLGPPGPPGL----GGKGLPGPPGEA 126
           G DG   P  A                  PG  G +GP GP GL    GG G  GPPGE 
Sbjct: 183 GPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEP 242

Query: 127 GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGPPGP 185
           G  GP G IG RGP GP G PG  G PG  G PG  G     GA          PG PG 
Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGF-------PGAPGL 295

Query: 186 PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGD 245
           PG+ G +G  G +G +GEVG  G KG+ GP GP G  G +G +G  G RG  GP G PG 
Sbjct: 296 PGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQ 355

Query: 246 R---------GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGP 296
           R         GP+G  G PG  G PG  G +GE GP G RGP+G  G+ G  G P   GP
Sbjct: 356 RGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPP---GP 412

Query: 297 SGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGS---KGEKGERGR 353
            G PG+PG  G +G PG  G  G  G +G PG  GP G PG  G  G    +G+ G+ G 
Sbjct: 413 VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGV 472

Query: 354 AGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGD 413
            G  GEAGP GEPG  G  G  G  GE G RG  G  G  GPPG  G RG  G +G  G 
Sbjct: 473 PGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGS 532

Query: 414 PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGE 473
            GLPGP+G +G+ G  G  G  G +GD G  G  GLPG +G  G  G+ GP+G+ G  G 
Sbjct: 533 DGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGA 592

Query: 474 LGPKGTQGPNGTSGVQGVPGP---PGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG 530
            G  G  GP G+ G++G PG    PGP G  G PG PG  G  GVPG+  +  +  E+  
Sbjct: 593 PGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEV-- 650

Query: 531 GMISEQIAQLAAHLRKPLAPGSIGRPGPAGP------PGPPGPPGSIGHPGARGPPGYRG 584
                     +  +  P   G  G  GP GP      PGPPGPPG  G PG +G PG  G
Sbjct: 651 --------GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPG 702

Query: 585 PTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGP 643
             G LG  G RGN G+RG+ G  G  G  G  G  GP GP+G PG S     G PG+ GP
Sbjct: 703 AVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPS-----GTPGDTGP 757

Query: 644 PGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678
           PG  G+PG  G  GTPG            GG+GEK
Sbjct: 758 PGLQGMPGERGIAGTPG-------PKGDRGGIGEK 785



 Score =  370 bits (950), Expect = e-102
 Identities = 213/484 (44%), Positives = 237/484 (48%), Gaps = 38/484 (7%)

Query: 16   LGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE 75
            +GE  A   A   G  G PGP GPPG  G  G  GE GP GL GPPG +G PG  G+ G 
Sbjct: 782  IGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGP 841

Query: 76   AGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
             G  G  G  G  G+ G  G  G PG++G  G PGP GL G   PGP G  GV G  GG 
Sbjct: 842  TGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS--PGPHGPNGVPGLKGGR 899

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPT 195
            G +GPPG +G PG  G  GPPGP G PG  P G        +  PG  GPPG+ G  G  
Sbjct: 900  GTQGPPGATGFPGSAGRVGPPGPAGAPG--PAGP-------LGEPGKEGPPGLRGDPGSH 950

Query: 196  GYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPP 255
            G  G++G  G  G  GD G PG  G PG  G  GP G  G  G +G PG RG  G  G P
Sbjct: 951  GRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLP 1010

Query: 256  GIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLD 315
            G  G PGK G           G  GD G PGP G PG  GP GEPG  G  G +G PG D
Sbjct: 1011 GPAGTPGKVGP---------TGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061

Query: 316  GQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMP 375
            G  GE G  G PG  G  G  G PG  G  G  G+ G+ G+ G  GP G PG  G  G+P
Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP 1121

Query: 376  GERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAA 435
            G +G  G +G  G  G +G  G  G  G QG  G  G  G  G  G+ G  G RGP G  
Sbjct: 1122 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPV 1181

Query: 436  GPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPP 495
            GP G +G  G          LGP G  G +G  G  G  GP G  GP         PGPP
Sbjct: 1182 GPSGKEGNPG---------PLGPIGPPGVRGSVGEAGPEGPPGEPGP---------PGPP 1223

Query: 496  GPLG 499
            GP G
Sbjct: 1224 GPPG 1227



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 48/128 (37%), Positives = 54/128 (42%), Gaps = 35/128 (27%)

Query: 554 GRPGPAGPPG-PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLD 612
           GR G  G PG  P   G  G PG  GPPG +GP GE G                      
Sbjct: 110 GRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERG---------------------- 147

Query: 613 GPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVL 672
            P+G  GP+GPQG+ G           EPG PG PG PG  G    PG    S    A +
Sbjct: 148 -PKGRPGPRGPQGIDG-----------EPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQM 195

Query: 673 GGVGEKSG 680
            G+ EKSG
Sbjct: 196 AGLDEKSG 203


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  516 bits (1328), Expect = e-146
 Identities = 315/706 (44%), Positives = 359/706 (50%), Gaps = 106/706 (15%)

Query: 32   GPPGPPGPPGKPGQDGIDGEA-----GPPG------LPGPPGPKGAPGKPGKPGEAGLPG 80
            GPPGPPG PG  GQ GI G+      GPPG      +PG  GP+G PG PG  G AG+PG
Sbjct: 742  GPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPG 801

Query: 81   LPGVDGLTGRDGPPGPKGAPG------ERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGG 134
              G+ G  GR+G  G  G PG      ERG+ G PG PGL   G PG PG  G  G PG 
Sbjct: 802  FLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGL--PGYPGSPGAPGGKGQPGD 859

Query: 135  IGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGP 194
            +G  GP G  GLPGLPG PG  GPPG PG+ P    D   P   PPGP GP G+PGF G 
Sbjct: 860  VGPPGPAGMKGLPGLPGRPGAHGPPGLPGI-PGPFGDDGLPG--PPGPKGPRGLPGFPGF 916

Query: 195  TGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGF--- 251
             G +G+ G  G  G KG+PG  G +GLPG       RGLRG  G +GPPGD G +     
Sbjct: 917  PGERGKPGAEGCPGAKGEPGEKGMSGLPGD------RGLRGAKGAIGPPGDEGEMAIISQ 970

Query: 252  RGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGV-AGPSGEPGMPGKDGQNG 310
            +G PG PG PG  G  GERG +G  G +G  G PG  G PG   G  GE G PG  G  G
Sbjct: 971  KGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPG 1030

Query: 311  VPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGE----LGEAGPSGEP 366
             PG  G +G  G  G PG++G  G PG PG +G  G +G +G  G+     G  GP GEP
Sbjct: 1031 PPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEP 1090

Query: 367  GVPG---------DAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLP 417
            G PG         + G+PG +G  G  G  G  G  GPPG PG  G  G +G  G+ G P
Sbjct: 1091 GSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDP 1150

Query: 418  GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGL--VGP---------KG 466
            GP+GL+GD G  GP G  GP G  G+ G  GL G KG  G SGL  VGP         KG
Sbjct: 1151 GPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKG 1210

Query: 467  ESGSRGELG-----PKGTQGPNGTSGVQGVPGP-------------PGPLGLQGVPGVPG 508
            E G  G  G     P+G +GP G  G  G PGP             PGP G QG PG  G
Sbjct: 1211 ERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDG 1270

Query: 509  ITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPP 568
              G PG PG   S   +R                       PG  G PGP GPPGPPGPP
Sbjct: 1271 PRGAPGPPGLPGSVDLLRG---------------------EPGDCGLPGPPGPPGPPGPP 1309

Query: 569  GSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQG---PQG 625
            G  G PG  G  G +GP G  G  GP G  G  G+KG     L GP G +GP G   P+G
Sbjct: 1310 GYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKG-----LPGPPGRKGPTGLPGPRG 1364

Query: 626  VPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTS--ACQG 669
             PG   D  D  P  PG PG PG+ G  GA G PG+   S   C+G
Sbjct: 1365 EPGPPADVDD-CPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKG 1409



 Score =  493 bits (1270), Expect = e-139
 Identities = 341/865 (39%), Positives = 389/865 (44%), Gaps = 246/865 (28%)

Query: 31   PGPPGPPGPPGKPGQDGIDGEAGPPGL------PGPPGPKGAPGKPGKPGEAGLPGLPG- 83
            PGP GPPGPPG PG+ G  G+ G PG       PGPPG +G PG PGK G +G PG  G 
Sbjct: 496  PGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGA 555

Query: 84   --------VDGLTGRDGPPGPKGAPGERGS---------LGPPGPPG------LGGKGLP 120
                    V G  G  GP GP G PG+ GS          G PGPPG       GGKG P
Sbjct: 556  KGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFP 615

Query: 121  ---GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPP------------------------ 153
               GPPG+AG  GPP G+G  GPPG  G PG+PG P                        
Sbjct: 616  GPLGPPGKAGPVGPP-GLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPG 674

Query: 154  --------GPPGPPGHPGVLPEGAT----------------------------DLQCPSI 177
                    GPPGP G PG  P+GA                             D+  P  
Sbjct: 675  RHGPPGFDGPPGPKGFPG--PQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGF 732

Query: 178  ------CPPGPPGPPGMPGFK--------------GPTGYKGEQGEVGKDGEKGDPGPP- 216
                   P GPPGPPG PG                GP G +G  G  G  G +GDPG P 
Sbjct: 733  GGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPG 792

Query: 217  --GPAGLPGSVGLQGPRGLR---GLPGPLGPPG---DRGPIGFRGPPGIPGAP------- 261
              GPAG+PG +GL+GP+G     G PG  GPPG   +RG  G  G PG+PG P       
Sbjct: 793  AEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPG 852

Query: 262  --GKAGDRGERGPEGFRGPKGDLGRP---GPKGTPGVAGPSGE---PGMPGKDGQNGVPG 313
              G+ GD G  GP G +G  G  GRP   GP G PG+ GP G+   PG PG  G  G+PG
Sbjct: 853  GKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPG 912

Query: 314  LDGQKGEAGRNGA---------PGEKGPNGLPGLPGRAGSKGEKGERGRAGE---LGEAG 361
              G  GE G+ GA         PGEKG +GLPG  G  G+KG  G  G  GE   + + G
Sbjct: 913  FPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKG 972

Query: 362  PSGEPGVPGDAGMPGE-------------------------RGEAGHRGSAGALGPQGPP 396
              GEPG PGD G PGE                         RGE G +G  G  GP GPP
Sbjct: 973  TPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPP 1032

Query: 397  GAPGVR---GFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAA-------GPKGDQGIAGS 446
            G+ G+R   GF G  G  G+PG PGP G  G  G RGP G         GP G +G  GS
Sbjct: 1033 GSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGS 1092

Query: 447  DGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP---------GPPGP 497
             G PG  G  G  GL G +G  GS G  GP G+ GP G  G  G+P         G PGP
Sbjct: 1093 PGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGP 1152

Query: 498  LGLQ---GVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIG 554
             GLQ   G+PG PGI G  G PG             G+  ++  + A+ L     PG +G
Sbjct: 1153 RGLQGDPGIPGPPGIKGPSGSPGLNGLH--------GLKGQKGTKGASGLHDVGPPGPVG 1204

Query: 555  RPGPAG-----------PPGPPGPPGSIGHPGARGPPGYRGPTG----ELGDPGPRGNQG 599
             PG  G           PPGP G  G  G PG+ GPPG  G TG    ++ DPGP G+QG
Sbjct: 1205 IPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQG 1264

Query: 600  DRGDKGAAGA--------------------GLDGPEGDQGPQGPQGVPG----TSKDGQD 635
              G  G  GA                    GL GP G  GP GP G  G      KDGQ 
Sbjct: 1265 PPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQK 1324

Query: 636  GAPGEPGPPGDPGLPGAIGAQGTPG 660
            G  G PGP G  G PG  G +G PG
Sbjct: 1325 GPVGFPGPQGPHGFPGPPGEKGLPG 1349



 Score =  481 bits (1238), Expect = e-136
 Identities = 316/781 (40%), Positives = 368/781 (47%), Gaps = 171/781 (21%)

Query: 28   VGLPGPPG--------------PPGPPGKPGQDGIDGEAGPPG----LPGPPGPKGAPGK 69
            VG PGPPG              PPGP G PG  G+ GEAG PG     PG PG  G+PG 
Sbjct: 384  VGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGL 443

Query: 70   PGKPGEAGLPGL---------PGVDGLTGRDGPPGPKGAPGERGS----------LGPPG 110
            PG PG  GLPG          PG  G+ G+ GPPG +G  GE+G+          +GPPG
Sbjct: 444  PGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPG 503

Query: 111  PPGLGG----------------KGLPGPPGEAGVSGPPGGIGLRGPPGPSG--------- 145
            PPGL G                KG PGPPG  G  G PG  G  GPPG  G         
Sbjct: 504  PPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSR 563

Query: 146  LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGP-----PGMPGFKGPTGYKGE 200
            + G  G  GP GPPG PG       D        PGPPG      PG  GF GP G  G+
Sbjct: 564  VKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGK 623

Query: 201  QGEVGKDGEKGDPGPPGPAG---LPGSVGLQGPRGLRG-----------LPGPLGPPGDR 246
             G VG  G  G PGPPG  G   +PG  G++GP GL+G            PG  GPPG  
Sbjct: 624  AGPVGPPG-LGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFD 682

Query: 247  GPIGFRGPPGIPGAPGKAGDRGERG------------PEGFRGPKGDLGRPGPKGTPGVA 294
            GP G +G PG  GAPG +G  G +G            P GFRG  GD G  G KG+  V 
Sbjct: 683  GPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPV- 741

Query: 295  GPSGEPGMPGKDGQNGVPGLD-----GQKGEAGRNGAPGEKGPNGLPGLPGRAGS----- 344
            GP G PG PG +GQ G+PG       G  G+ G +G PG KGP G PG PG  G      
Sbjct: 742  GPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPG 801

Query: 345  ----KGEKGERGRAGELGEAGPSGE------PGVPGDAGMPG---ERGEAGHRGSAGALG 391
                KG KG  G AG  G  GP G       PG+PG  G+PG     G  G +G  G +G
Sbjct: 802  FLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVG 861

Query: 392  PQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKG---------DQG 442
            P GP G  G+ G  G+ G+ G PGLPG  G  GD G  GP G  GP+G         ++G
Sbjct: 862  PPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERG 921

Query: 443  IAGSDGLPGDKGELGP---SGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLG 499
              G++G PG KGE G    SGL G +G  G++G +GP G +G       +G PG PGP G
Sbjct: 922  KPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPG 981

Query: 500  LQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPA 559
              G PG  G  G PG+ G+     R                  H  +P   G  G+PGP 
Sbjct: 982  DDGFPGERGDKGTPGMQGRRGEPGRY------------GPPGFHRGEP---GEKGQPGPP 1026

Query: 560  GPPGPPGP------------PGSIGHPGARGPPGY------RGPTGELGDPGPR-GNQGD 600
            GPPGPPG             PG  G PG+ GPPG+      RGP G  GDP    G  G 
Sbjct: 1027 GPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGP 1086

Query: 601  RGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            +G+ G+ G       G  G  G QG+PG    G  G+PG PGPPG  G PG  G  G PG
Sbjct: 1087 KGEPGSPGC-----PGHFGASGEQGLPGIQ--GPRGSPGRPGPPGSSGPPGCPGDHGMPG 1139

Query: 661  I 661
            +
Sbjct: 1140 L 1140



 Score =  479 bits (1233), Expect = e-135
 Identities = 321/781 (41%), Positives = 370/781 (47%), Gaps = 145/781 (18%)

Query: 29   GLPGPPGPPGPPGKPGQDGID--GEAGPPGLPGP---PGPKGAPGKPGKPGEAGLPGLPG 83
            G+PG  G PGPPG+ G+ GI   GE G PG PGP   PG  G+PG PG  GE GL G PG
Sbjct: 276  GIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPG 335

Query: 84   VDGLTGRDGPPGPKGAPGERGSL--------GPPGPPGLGGK----GLPGPPGEAGVSGP 131
            + GL G  G PG +G PG  G L        GPPG PG  G+    G  GPPG  G+ G 
Sbjct: 336  LFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGR 395

Query: 132  PGGI--GLRGPPGPSGLPGLPGPPGPPGPPGHPGVLP-----------EGATDLQ----- 173
            PG    G+ GPPGP G PGLPG PG  G PG P   P            GA  LQ     
Sbjct: 396  PGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGS 455

Query: 174  CPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDG----EKGDPGPPGPAGLPGSVGLQG 229
                C  G PGP G+ G  GP G +G +GE G +G    E G  GPPGP GLPG    QG
Sbjct: 456  SVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGR---QG 512

Query: 230  PRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEG------FRGPKGDLG 283
             +G  GLPG LG  GD GP G  GPPG+PG  G +G  G +G +G       +G KG+ G
Sbjct: 513  SKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERG 572

Query: 284  RPGPKGTPGVAGPSGEPGMPGKDGQNGVPG-----LDGQKGEAGRNGAPGEKGPNGLPGL 338
              GP G PG  G  G  G  G+ G  G PG       G KG  G  G PG+ GP G PGL
Sbjct: 573  PDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL 632

Query: 339  PGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDA-----GMPGERGEAGHRGSAGALGPQ 393
             G  G  GE+G  G  G  G  GP G  G  GD        PG  G  G  G  G  G  
Sbjct: 633  -GFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFP 691

Query: 394  GPPGAPGVRGFQGQKGSMGDPG---LPGPQGLRGDVGDRG--------PGGAAGPKGDQG 442
            GP GAPG+ G  G KG  G PG   +PGP G RGD+GD G        P G  GP G  G
Sbjct: 692  GPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPG 751

Query: 443  IAGSDGLPGDK--GELGPSG---------LVGPKGESGSRGELGP---------KGTQGP 482
            + G  G+PGD   G LGP G         + GP+G+ G  G  GP         KG +G 
Sbjct: 752  VNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGR 811

Query: 483  NGTSGVQGVPGPPG---PLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQ 539
             G +G  GVPGPPG     G  G+PG PG+ G PG PG    + +  ++ G      +  
Sbjct: 812  EGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDV-GPPGPAGMKG 870

Query: 540  LAAHLRKPLAPGSIGRPGPAGP------PGPPGP------PGSIGHPGARGPPGYRGPTG 587
            L     +P A G  G PG  GP      PGPPGP      PG  G PG RG PG  G  G
Sbjct: 871  LPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPG 930

Query: 588  ELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQG---------------PQGPQGVPGTSK 631
              G+PG +G  G  GD+G  GA G  GP GD+G               P G  G PG   
Sbjct: 931  AKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERG 990

Query: 632  D-----------------------GQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQ 668
            D                       G+ G  G+PGPPG PG PG+ G +G  G       Q
Sbjct: 991  DKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQ 1050

Query: 669  G 669
            G
Sbjct: 1051 G 1051



 Score =  479 bits (1232), Expect = e-135
 Identities = 320/779 (41%), Positives = 366/779 (46%), Gaps = 154/779 (19%)

Query: 24  GAQRVGLPGP------------PGP---------------------------PGPPGKPG 44
           G   VG+ G             PGP                           PGPPG+ G
Sbjct: 232 GNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKG 291

Query: 45  QDGI--DGEAGPPGLPGP---PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGA 99
           + GI   GE G PG PGP   PG  G+PG PG  GE GL G PG+ GL G  G PG +G 
Sbjct: 292 ESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGH 351

Query: 100 PGERGSL--------GPPGPPGLGGK----GLPGPPGEAGVSGPPGG--IGLRGPPGPSG 145
           PG  G L        GPPG PG  G+    G  GPPG  G+ G PG    G+ GPPGP G
Sbjct: 352 PGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQG 411

Query: 146 LPGLPG-------------PPGPPGPPGHPGVLPEGATDLQ-----CPSICPPGPPGPPG 187
            PGLPG              PG PG PG PG+   GA  LQ         C  G PGP G
Sbjct: 412 FPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGL--PGAPGLQGLPGSSVIYCSVGNPGPQG 469

Query: 188 MPGFKGPTGYKGEQGEVGKDG----EKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPP 243
           + G  GP G +G +GE G +G    E G  GPPGP GLPG    QG +G  GLPG LG  
Sbjct: 470 IKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGR---QGSKGDLGLPGWLGTK 526

Query: 244 GDRGPIGFRGPPGIPGAPGKAGDRGERGPEG------FRGPKGDLGRPGPKGTPGVAGPS 297
           GD GP G  GPPG+PG  G +G  G +G +G       +G KG+ G  GP G PG  G  
Sbjct: 527 GDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSH 586

Query: 298 GEPGMPGKDGQNGVPG-----LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG 352
           G  G  G+ G  G PG       G KG  G  G PG+ GP G PGL G  G  GE+G  G
Sbjct: 587 GRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGERGHPG 645

Query: 353 RAGELGEAGPSGEPGVPGD-----AGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ 407
             G  G  GP G  G  GD        PG  G  G  G  G  G  GP GAPG+ G  G 
Sbjct: 646 VPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGH 705

Query: 408 KGSMGDPG---LPGPQGLRGDVGDRG--------PGGAAGPKGDQGIAGSDGLPGDK--G 454
           KG  G PG   +PGP G RGD+GD G        P G  GP G  G+ G  G+PGD   G
Sbjct: 706 KGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFG 765

Query: 455 ELGP---------SGLVGPKGESGSRGELGP---------KGTQGPNGTSGVQGVPGPPG 496
            LGP          G+ GP+G+ G  G  GP         KG +G  G +G  GVPGPPG
Sbjct: 766 HLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPG 825

Query: 497 PLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRP 556
               +G PG+PG  G PG PG   +        GG                  PG  GRP
Sbjct: 826 HSCERGAPGIPGQPGLPGYPGSPGAP-------GGKGQPGDVGPPGPAGMKGLPGLPGRP 878

Query: 557 GPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA------- 609
           G  GPPG PG PG  G  G  GPPG +GP G  G PG  G +G  G +G  GA       
Sbjct: 879 GAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEK 938

Query: 610 GLDGPEGDQGPQGPQGVPGTSKD-------GQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
           G+ G  GD+G +G +G  G   D        Q G PGEPGPPGD G PG  G +GTPG+
Sbjct: 939 GMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGM 997



 Score =  476 bits (1226), Expect = e-134
 Identities = 307/765 (40%), Positives = 363/765 (47%), Gaps = 143/765 (18%)

Query: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
           G PGPPGP GP G  G  G  G +G  G+ G  GP GA G  G  G  G+PG PG+DG+ 
Sbjct: 65  GPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIP 124

Query: 89  GRDGPPGPKGAPGE---------------RGSLGPPGPPGLGG---------------KG 118
           G  GPPGP+G PG                RG+LGP GP G  G               KG
Sbjct: 125 GHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKG 184

Query: 119 LPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGV-------------- 164
           + G  G+ G+ G PG  G  GP GP+G PG PG  GPPG PG PG+              
Sbjct: 185 IQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGD 244

Query: 165 --------LPEGATDLQCPSIC----PPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGD 212
                    P     ++ P  C      G  G PGM G  GP G KGE G +G  GEKG 
Sbjct: 245 PGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG-IGAKGEKGI 303

Query: 213 PGPPGPAGLPGS------------VGLQGPRGLRGLPGPLGPPGDRG-----------PI 249
           PG PGP G PGS            +GL G  GL GL GP G PG+RG           P+
Sbjct: 304 PGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPL 363

Query: 250 GFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP--KGTPGVAGPSGEPGMPGKDG 307
             +GPPG PG PG+ G+ G+ GP    GP G LGRPG    G  G  GP G PG+PG  G
Sbjct: 364 PLKGPPGDPGFPGRYGETGDVGPP---GPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPG 420

Query: 308 QNGVPGL-DGQKGEAGRNGAPGEKGPNGLPGLPGRA------GSKGEKGERGRAGELGEA 360
           + G+PG  D   G+ G+ G+PG  G  GL GLPG +      G+ G +G +G+ G  G  
Sbjct: 421 EAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGR 480

Query: 361 GPSGEP-------------GVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ 407
           GP GE              G PG  G+PG +G  G  G  G LG +G PG PG  G  G 
Sbjct: 481 GPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGL 540

Query: 408 KGSMGDPGLPGPQGLRGDV---------GDRGPGGAAGPKGDQGIAGSDGLPGDKGELGP 458
            G  G  G PG +G +GD+         G+RGP G  G  G  G  G DG  G+KG+ GP
Sbjct: 541 PGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGP 600

Query: 459 SG--LVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVP 516
            G       G  G  G LGP G  GP G  G+ G PGPPG  G  GVPG PG+ G  G+ 
Sbjct: 601 PGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGERGHPGVPGHPGVRGPDGLK 659

Query: 517 GKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGA 576
           G++          G  IS  +     H      PG  G PGP G PGP G PG  G  G 
Sbjct: 660 GQK----------GDTISCNVTYPGRH----GPPGFDGPPGPKGFPGPQGAPGLSGSDGH 705

Query: 577 RGPPGYRGPTGELGDPGPRGNQGD---RGDKGAAGAGLDGPEGDQGPQGPQGVPG----- 628
           +G PG  G     G PG RG+ GD    G+KG++  G  GP G  G  G +G+PG     
Sbjct: 706 KGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFG 765

Query: 629 ----TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG 669
                 K G  G PG  GP GDPG PGA G  G PG       +G
Sbjct: 766 HLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKG 810



 Score =  473 bits (1216), Expect = e-133
 Identities = 311/737 (42%), Positives = 356/737 (48%), Gaps = 126/737 (17%)

Query: 29   GLPGPPG-----------PPGPPGKPGQDGIDGEAGPPGLPG--------------PPGP 63
            G PGPPG           PPG PG PG+ G  G+ GPPG PG              PPGP
Sbjct: 350  GHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGP 409

Query: 64   KGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLG-GKGLPGP 122
            +G PG PG PGEAG+PG P  D   G+ G PG  G PG  G  G PG   +    G PGP
Sbjct: 410  QGFPGLPGLPGEAGIPGRP--DSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGP 467

Query: 123  PGEAGVSGPPGGIGLRGPPGPSGLPGL----PGPPGPPGPPGHPGVLPEGAT-DLQCPSI 177
             G  G  GPPGG   RGP G  G  GL    PGP GPPGPPG PG   +G+  DL  P  
Sbjct: 468  QGIKGKVGPPGG---RGPKGEKGNEGLCACEPGPMGPPGPPGLPG--RQGSKGDLGLPGW 522

Query: 178  C-------PPGPPGPPGMPG---FKGPTGYKGEQGEV------GKDGEKGDPGPPGPAGL 221
                    PPG  GPPG+PG     GP G KG +G++      G  GE+G  GPPG  G 
Sbjct: 523  LGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQ 582

Query: 222  PGSVGLQGPRGLRG-----------------LPGPLGPPGDRGPIG-----FRGPPGIPG 259
            PGS G  G  G +G                  PGPLGPPG  GP+G     F GPPG  G
Sbjct: 583  PGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERG 642

Query: 260  APGKAGDRGERGPEGFRGPKGD-----LGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGL 314
             PG  G  G RGP+G +G KGD     +  PG  G PG  GP G  G PG  G  G+ G 
Sbjct: 643  HPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGS 702

Query: 315  DGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGER--GRAGELGEAGPSGEPGVPGD- 371
            DG KG  G  G     GP G  G  G  G  GEKG    G  G  G  G +G+ G+PGD 
Sbjct: 703  DGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDP 762

Query: 372  -------------AGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPG 418
                         +G+PG +G  G  G  GA GP G PG  G++G +G++G  G PG+PG
Sbjct: 763  AFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPG 822

Query: 419  PQGL---RGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELG 475
            P G    RG  G  G  G  G  G  G  G  G PGD G  GP+G+ G  G  G  G  G
Sbjct: 823  PPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHG 882

Query: 476  PKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISE 535
            P G  G  G  G  G+PGPPGP G +G+PG PG  G+ G PG E         C G   E
Sbjct: 883  PPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEG--------CPGAKGE 934

Query: 536  QIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSI------GHPGARGPPGYRGPTGEL 589
               +  + L     PG  G  G  G  GPPG  G +      G PG  GPPG  G  GE 
Sbjct: 935  PGEKGMSGL-----PGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989

Query: 590  GDPGPRGNQGDRGDKGAAGA-----GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPP 644
            GD G  G QG RG+ G  G      G  G +G  GP GP G PG++  G  G  G PG P
Sbjct: 990  GDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGST--GLRGFIGFPGLP 1047

Query: 645  GDPGLPGAIGAQGTPGI 661
            GD G PG+ G  G  GI
Sbjct: 1048 GDQGEPGSPGPPGFSGI 1064



 Score =  461 bits (1187), Expect = e-130
 Identities = 287/673 (42%), Positives = 334/673 (49%), Gaps = 95/673 (14%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88
            G+PG PG PG PG PG  G  G+ G  G PGP G KG PG PG+PG  G PGLPG+ G  
Sbjct: 834  GIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPF 893

Query: 89   GRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPG 148
            G DG PGP G  G RG  G PG PG  GK  PG  G  G  G PG  G+ G PG  GL G
Sbjct: 894  GDDGLPGPPGPKGPRGLPGFPGFPGERGK--PGAEGCPGAKGEPGEKGMSGLPGDRGLRG 951

Query: 149  LPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGF------KGPTGYKGEQG 202
              G  GPPG  G   ++ +  T         PG PGPPG  GF      KG  G +G +G
Sbjct: 952  AKGAIGPPGDEGEMAIISQKGT---------PGEPGPPGDDGFPGERGDKGTPGMQGRRG 1002

Query: 203  EVGK----------DGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGF- 251
            E G+           GEKG PGPPGP G PGS GL+G  G  GLPG  G PG  GP GF 
Sbjct: 1003 EPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFS 1062

Query: 252  ------------------------RGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP 287
                                    +G PG PG PG  G  GE+G  G +GP+G  GRPGP
Sbjct: 1063 GIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP 1122

Query: 288  KGT---PGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGS 344
             G+   PG  G  G PG+ G+ G+ G PG  G +G+ G  G PG KGP+G PGL G  G 
Sbjct: 1123 PGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGL 1182

Query: 345  KGEKGERGRAG--ELGEAGPSGEPGVPGDAGMPGERGEA--GHRGSAGALGPQGPPGAPG 400
            KG+KG +G +G  ++G  GP G PG+ G+ G PG  G +  G RG  G  GP G  G PG
Sbjct: 1183 KGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPG 1242

Query: 401  VRGFQGQK-------GSMGDPGLPGPQGLRGDVGDRGPGGAA----GPKGDQGIAGSDGL 449
              G  G+        G  GD G PGP G RG  G  G  G+     G  GD G+ G  G 
Sbjct: 1243 PAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGP 1302

Query: 450  PGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGI 509
            PG  G  G  G  G  G+ G +G +G  G QGP+G  G  G  G PGP G +G  G+PG 
Sbjct: 1303 PGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGP 1362

Query: 510  TGKPGVPGKEASEQRIRELCG--GMISEQIAQLAAHLRKPLAPGSIGRP------GPAGP 561
             G+PG P       RI  L G  GM   + A     +R P  PG  G P      G  G 
Sbjct: 1363 RGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGV 1422

Query: 562  PGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDG-------P 614
            PG PGPPG  G  G  G PG  GP G +GDPGP+G           G G  G        
Sbjct: 1423 PGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG----------FGPGYLGGFLLVLHS 1472

Query: 615  EGDQGPQGPQGVP 627
            + DQ P  P G+P
Sbjct: 1473 QTDQEPTCPLGMP 1485



 Score =  332 bits (852), Expect = 5e-91
 Identities = 218/540 (40%), Positives = 257/540 (47%), Gaps = 79/540 (14%)

Query: 166 PEGATDLQ-CPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS 224
           P G  D   C  +   G  GPPG PG +GP G  G  G +G  GEKG  G  GP G  G 
Sbjct: 46  PCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGD 105

Query: 225 VGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGR 284
            G +GP G+ G PG  G PG  GP G RG PG+ G  G  GD G  G  G  GP G LG 
Sbjct: 106 KGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGH 165

Query: 285 PGPKG-----------TPGVAGPSGEPGMPGKDGQ---NGVPGLDGQKGEAGRNGAPGEK 330
           PG KG             G+ G  G+PG+PG  G     G  G  G  GE G  G PG+ 
Sbjct: 166 PGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQP 225

Query: 331 GPNGLPGLPGRAGSKGEKGERGRAGELGEAGPS------------GEPGVPGDAGMPGER 378
           G  GL G PG  G KG+ G+ G  G+ G  GP+            GE G+ G  GM G  
Sbjct: 226 GRPGLKGNPG-VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLP 284

Query: 379 GEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPK 438
           G  G +G +G +G +G  G PG  G +G  GS G PG PG +G  G VGD G  G  GPK
Sbjct: 285 GPPGRKGESG-IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPK 343

Query: 439 GDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPP--- 495
           GD G  G  G PG      P  L GP G+ G  G  G  G  GP G  G+ G PG     
Sbjct: 344 GDPGNRGHPGPPGVL-VTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAG 402

Query: 496 --GPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSI 553
             GP G QG PG+PG+ G+ G+PG+  S                           AP   
Sbjct: 403 MIGPPGPQGFPGLPGLPGEAGIPGRPDS---------------------------AP--- 432

Query: 554 GRPGPAGPPGPPGPPGSIGHPGAR------GPPGYRGPTGELGDPGPRGNQGDRGDKGAA 607
           G+PG  G PG PG PG  G PG+       G PG +G  G++G PG RG +G++G++G  
Sbjct: 433 GKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLC 492

Query: 608 GAGLDGPEGDQGPQGPQGVPGTSKD-------GQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            A   GP G  GP G  G  G+  D       G  G PG PG  G PGLPG  GA G PG
Sbjct: 493 -ACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPG 551



 Score =  127 bits (318), Expect = 4e-29
 Identities = 75/164 (45%), Positives = 82/164 (50%), Gaps = 7/164 (4%)

Query: 28   VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGL 87
            VG PGP GP G PG PG+ G+ G  G  G  G PGP+G PG P    +   P +PG+ G 
Sbjct: 1327 VGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDC--PRIPGLPGA 1384

Query: 88   TGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147
             G  GP G  G PG R   GP GP   G  GL G  G  GV G PG  G +G  G  G P
Sbjct: 1385 PGMRGPEGAMGLPGMR---GPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYP 1441

Query: 148  GLPGPPGPPGPPGHPGVLPE--GATDLQCPSICPPGPPGPPGMP 189
            G PGPPGP G PG  G  P   G   L   S     P  P GMP
Sbjct: 1442 GGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQTDQEPTCPLGMP 1485



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 29/52 (55%), Positives = 31/52 (59%), Gaps = 4/52 (7%)

Query: 27   RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPG-KPGEAG 77
            R G+ G PG PGPPG+ G  G DG    PG PGPPGP G PG  G  PG  G
Sbjct: 1416 RRGVDGVPGSPGPPGRKGDTGEDGY---PGGPGPPGPIGDPGPKGFGPGYLG 1464



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 1/66 (1%)

Query: 613 GPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVL 672
           GP G +       VP     G  G PG  GP G  G PG IG  G  G+       GA  
Sbjct: 45  GPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAA- 103

Query: 673 GGVGEK 678
           G  G+K
Sbjct: 104 GDKGDK 109


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  513 bits (1320), Expect = e-145
 Identities = 311/712 (43%), Positives = 360/712 (50%), Gaps = 87/712 (12%)

Query: 35   GPPGPPGK-PGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGV--------- 84
            G PG PG   G     G  GPPG+PGPPGP G PG  G PG  GLPG PG+         
Sbjct: 888  GMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPI 947

Query: 85   ----------DGLTGRDGPPGPKGAPGERGSLGPPGPPGL-------------------- 114
                      D + G+   PG     GE+G  G PG PGL                    
Sbjct: 948  EQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARG 1007

Query: 115  -GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-------- 165
               +G PG  G  G+ GPPG  G RG  GP G+ G PGPPGP GPPG PG +        
Sbjct: 1008 DNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGL 1067

Query: 166  --PEGATDLQCPSICPPGPPGPPGMPGFKGPTGY---KGEQGEVGKDGEKGDPGPPGPAG 220
                G T L       PGPPG PG PG  GP G    KGE+G  G  GEKG+PGPPG  G
Sbjct: 1068 QGERGLTGLTGDK-GEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEG 1126

Query: 221  LPGSVGLQGPRGLRGLPGPLGPPGDRG---PIGFRGPPGIPGAPGKAGDRG------ERG 271
            LPG  G  GPRG RG  G  G  GD+G     GF GPPG PG PGK G  G      E+G
Sbjct: 1127 LPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKG 1186

Query: 272  PEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKG 331
             EG RGP G  G PGP G PG+ GP+G  G+ GKDG+ G+ G  G  G  G  G PG KG
Sbjct: 1187 SEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKG 1246

Query: 332  PNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALG 391
              G PGLPG    KG+ G+ G  G  G  G  GEPG  G  G PG  G  G  G  G  G
Sbjct: 1247 KTGHPGLPG---PKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPG 1303

Query: 392  PQG--PPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGL 449
            P G    G  G RG  G++G  G PG PGP G  G  G+ G  GAAG +G  G  G  G 
Sbjct: 1304 PAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGP 1363

Query: 450  PGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGI 509
            PG KG+    G  G KG++G +G  G  G  GP G SG  G  GPPGP G +G PG PG 
Sbjct: 1364 PGPKGD---PGAAGQKGQAGEKGRAGMPG--GP-GKSGSMGPVGPPGPAGERGHPGAPGP 1417

Query: 510  TGKPGVPGKEAS----------EQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPA 559
            +G PG+PG   S          ++ IR+    M  E++A   + ++ P+   +   PG  
Sbjct: 1418 SGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA--PGRP 1475

Query: 560  GPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQG 619
            GPPG  G PG  G PG+ G PG  G  G  G PG RG  G +G+KG  G G+ G  G  G
Sbjct: 1476 GPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPG 1535

Query: 620  PQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAV 671
            P GPQG PG  K G  G  G+ G PG PG PG +G  G  G C+ S C GA+
Sbjct: 1536 PPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAM 1587



 Score =  491 bits (1265), Expect = e-139
 Identities = 303/735 (41%), Positives = 348/735 (47%), Gaps = 143/735 (19%)

Query: 25   AQRVGLPGPPGPPGP-----PGKPGQDGIDGEAGPPGLPGPPGPKGAPGK--PGKPGEAG 77
            A R G PGP G  GP     PGKPGQ G+ G  GPPGL G  G  G PG+   G  GE G
Sbjct: 738  AGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPG 797

Query: 78   LPGLPGVDGLTGRDGPPGP------KGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGP 131
             PGLPG+ GL G  GPPGP      +G+PG +G+ GP GPPG    G PG  G+ G +G 
Sbjct: 798  APGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGL 857

Query: 132  PGGIGLRGP------------------------------------PGPSGLPGLPGPPGP 155
             G  G +GP                                    PGP G PG+PGPPGP
Sbjct: 858  RGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGP 917

Query: 156  PGPPG------------HPGVLPE-GATDLQ---CPSICPPGPPGPPGMPGFKGPTGYKG 199
            PG PG             PG+  E G+  ++     SIC     G    PG+    G KG
Sbjct: 918  PGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKG 977

Query: 200  EQG-----------------------EVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGL 236
            +QG                       E   D  +GDPG  G  GLPG  GL G RG  G 
Sbjct: 978  DQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP 1037

Query: 237  PGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGP 296
            PG  G PG  GPIG   PPG PGA G  G  G +G  G  G  GD G PGP G PG  G 
Sbjct: 1038 PGMRGSPGPPGPIG---PPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGA 1094

Query: 297  SGEPGMPGKDGQNGVPGLDGQKGEAG---RNGAPGEKGPNGLPGLPGRAGSKGEKGERGR 353
            +G PG+PG  G+ G  G  G+KGE G     G PG  GP G  G  G  G+ GEKG++G 
Sbjct: 1095 TGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGF 1154

Query: 354  AGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQ---GPPGAPGVRGFQGQKGS 410
             G+ G  GP G PG PG  G PG  G    +GS G  GP    G PG PG  G QG  G 
Sbjct: 1155 QGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGL 1214

Query: 411  MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL---GPSGLVGPKGE 467
             G  G  G  GLRGD G  GP G  GP G +G  G  GLPG KG+    GP G  G  G 
Sbjct: 1215 DGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGA 1274

Query: 468  SGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQ--GVPGVPGITGKPGVPGKEASEQRI 525
             G  G +GP+G  GP G  G  G PG PGP G+   G+ G  G TG+ G+ G        
Sbjct: 1275 EGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLP------ 1328

Query: 526  RELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPP---GY 582
                                        G+PGP G PGPPG PG+ G  G  GPP   G+
Sbjct: 1329 ----------------------------GQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGF 1360

Query: 583  RGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPG 642
             GP G  GDPG  G +G  G+KG   AG+ G  G  G  GP G PG +  G+ G PG PG
Sbjct: 1361 YGPPGPKGDPGAAGQKGQAGEKGR--AGMPGGPGKSGSMGPVGPPGPA--GERGHPGAPG 1416

Query: 643  PPGDPGLPGAIGAQG 657
            P G PGLPG  G+ G
Sbjct: 1417 PSGSPGLPGVPGSMG 1431



 Score =  471 bits (1213), Expect = e-133
 Identities = 301/745 (40%), Positives = 345/745 (46%), Gaps = 149/745 (20%)

Query: 28   VGLPGP------PGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGL 81
            V LPGP      PGPPG  G PG+    G+AG  GL G  G  G PG PG PG  G PGL
Sbjct: 649  VALPGPSGEKGEPGPPG-FGLPGK---QGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGL 704

Query: 82   PGVDGLTGRDGPPGPK------------------GAPGERGSLGPPGPPGLGGKGLPGPP 123
             G  G+ G  GP G K                  G PG+ G  G  GP G+G  G PG P
Sbjct: 705  SGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQP 764

Query: 124  GEAGVSGPPGGIGLRGPPGP-----------------SGLPGLPGPPGPPGPPGHPGVLP 166
            G  GV GPPG  G++G PGP                  G+ GLPGP GPPGP G  G   
Sbjct: 765  GLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQG 824

Query: 167  EGATDLQCPSICPPGP--PGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGP---PGP--- 218
                      + PPG    GPPG  G +G TG +G  GE G  GEKG+PG    P     
Sbjct: 825  SPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDL 884

Query: 219  --AGLPGSVGL-------QGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGD--- 266
              +G+PG+ GL        GP+G  G+PGP GPPG  G  G  G  G+PG PG   +   
Sbjct: 885  IFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS 944

Query: 267  ----------------RGERGPEGF---RGPKGDLGRPGPKGTPGVA------------- 294
                            +G+R   G+   +G KGD G PG  G    A             
Sbjct: 945  LPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEE 1004

Query: 295  ----GPSGEPGMPGKDGQNGVPGLDGQKGE---AGRNGAPGEKGPNGLPGLPGRAGS--- 344
                   G+PG  G  G  G PGL GQ+GE    G  G+PG  GP G PG PG  GS   
Sbjct: 1005 ARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGL 1064

Query: 345  ---KGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV 401
               +GE+G  G  G+ GE GP G+PG PG  G PG  G  G RG  G+ G +G PG PG 
Sbjct: 1065 PGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGS 1124

Query: 402  RGFQGQKGSMGDPGLPGPQGLRGDVGDRG----PG--GAAGPKGDQGIAGSDGLPGDKGE 455
             G  G  G  G  G  GPQG  G+ GD+G    PG  G  GP G  G  GS G PG + E
Sbjct: 1125 EGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAE 1184

Query: 456  LGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGV 515
             G  G+ GP G  GS G  GP G QGP G  G+ G  G PG  G  G  G PG+ G PG 
Sbjct: 1185 KGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGF 1244

Query: 516  PGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPG 575
             GK                                G  G PGP G  G PGPPGS G PG
Sbjct: 1245 KGK-------------------------------TGHPGLPGPKGDCGKPGPPGSTGRPG 1273

Query: 576  ARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQD 635
            A G PG  GP G  G PG  G  G  G  G AG    G +GD+G  G +G+ G    GQ 
Sbjct: 1274 AEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGL--PGQP 1331

Query: 636  GAPGEPGPPGDPGLPGAIGAQGTPG 660
            G PG PGPPG+PG  GA G +G PG
Sbjct: 1332 GPPGHPGPPGEPGTDGAAGKEGPPG 1356



 Score =  459 bits (1182), Expect = e-129
 Identities = 313/773 (40%), Positives = 361/773 (46%), Gaps = 143/773 (18%)

Query: 24   GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGP------KGAPGKPGKP---- 73
            G+   GLPG PG  G PG  G+ G  GEAGP G PGPPGP      KGA G+P +P    
Sbjct: 579  GSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPAL 638

Query: 74   -----------------GEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGG 116
                             GE G PG PG  GL G+ G  G +G  G++G  G PG PG  G
Sbjct: 639  SNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGDPGTPG 697

Query: 117  K-GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGP-------PGPPGPPGHPGVLPEG 168
              G PG  GE GV GP G  G +G  G +  P L G        PG PGP G  G  PEG
Sbjct: 698  TTGRPGLSGEPGVQGPAGPKGEKGD-GCTACPSLQGTVTDMAGRPGQPGPKGEQG--PEG 754

Query: 169  ATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGE--KGDPGPPGPAGLPGSVG 226
                    +  PG PG PG+PG +GP G KG QGE G  G   +G  G PG  GLPG  G
Sbjct: 755  --------VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQG 806

Query: 227  LQGPRG---------------LRGLPGPLGPPGDR-----GPIGFRGPPGIPGAPGKAGD 266
            L GPRG               ++G  GP+GPPG       G  G +G  G+ G PG+ G 
Sbjct: 807  LPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGP 866

Query: 267  RGERGPEG-----------FRGPKGDLG-------RPGPKGTPGVAGPSGEPGMPGKDG- 307
            RGE+G  G           F G  G  G       +PGP+G PG+ GP G PG+PG  G 
Sbjct: 867  RGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGV 926

Query: 308  --QNGVPG-------------------------LDGQKGEAGRNGAPGEKGPNGLPGLPG 340
               NG+PG                         + GQ+   G     GEKG  G+PG+PG
Sbjct: 927  PGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPG 986

Query: 341  --RAGSKGEKGERGRAGEL------GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGP 392
                       ER RA E       G+ G  G PG+PG  G+PG+RGE G  G  G+ GP
Sbjct: 987  LDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGP 1046

Query: 393  QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGD 452
             GP G PG   F G  GS G PGL G +GL G  GD+G  G  G  G  G  G  GLPG 
Sbjct: 1047 PGPIGPPG---FPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGI 1103

Query: 453  KGELGPSGLVGPKGESG---SRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGI 509
            KGE G +G  G KGE G   S G  GP G  GP G  G QG  G  G  G QG PG PG 
Sbjct: 1104 KGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGP 1163

Query: 510  TGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPG 569
             G PG PGK  S         G    Q  + +  +R P   G  G PGP GPPG  GP G
Sbjct: 1164 PGPPGFPGKVGSP--------GPPGPQAEKGSEGIRGP--SGLPGSPGPPGPPGIQGPAG 1213

Query: 570  SIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGT 629
              G  G  G PG RG  G  G PG  G  G +G  G  G  L GP+GD G  GP G   T
Sbjct: 1214 LDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPG--LPGPKGDCGKPGPPG--ST 1269

Query: 630  SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSR 682
             + G +G PG  GP G PG PG +G  G PG    +      L G    +G R
Sbjct: 1270 GRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGER 1322



 Score =  434 bits (1116), Expect = e-121
 Identities = 310/848 (36%), Positives = 362/848 (42%), Gaps = 226/848 (26%)

Query: 29   GLPGPPGPPGPPGKPGQD--------------------GIDGEAGPPGLPGPPGPKGAPG 68
            GLPGPPG  G  G  G D                    G  G  GP GLPG  G KG  G
Sbjct: 343  GLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKG 402

Query: 69   K---------PGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGL 119
            +         PGKPG  G PG   V G  G+ G PG  G  G  G  GPPG PG  G GL
Sbjct: 403  EKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGL 462

Query: 120  PGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQ-CPSIC 178
            PG PG+ G  GPP      GP G  G  G+PG  GP G PG PGV  E     + CP++ 
Sbjct: 463  PGTPGDPG--GPP------GPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLP 514

Query: 179  P--------PGPPGPPGMPGFKGPT-------GYKGEQGE--------------VGKDGE 209
                     PG PGP G PG   P        G KGE+GE              V   G 
Sbjct: 515  EGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGA 574

Query: 210  KGDPGPP--GPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGA------- 260
             GD G P  G  GLPG  G+ G +G +G  G  GP G  GP G  GP GI GA       
Sbjct: 575  SGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEP 634

Query: 261  -----------------PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMP 303
                             PG +G++GE GP GF G  G  G+ G +G  G  G +G PG P
Sbjct: 635  CPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGDP 693

Query: 304  GKDGQNGVPGLDGQKGEAGRNGAPGEKGPN-----GLPG----LPGRAGSKGEKGERGRA 354
            G  G  G PGL G+ G  G  G  GEKG        L G    + GR G  G KGE+G  
Sbjct: 694  GTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPE 753

Query: 355  GELGEAGPSGEPGVPGDAGMPGERGEAGHRG--SAGALGPQGPPGAPGVRGFQGQKGSMG 412
            G +G  G  G+PG+PG  G PG +G  G  G    G  GPQG PGAPG+ G QG  G  G
Sbjct: 754  G-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRG 812

Query: 413  DPGLPGPQGLRGDVGDRGPGGAAGPKGD--QGIAGSDGLPGDKGELGPSGLVGPKGESGS 470
             PG  G +G +G  G +G  G  GP G    G  G DG  G  G  G  G  GP+GE G 
Sbjct: 813  PPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGE 872

Query: 471  RGE---------------------LGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGI 509
             GE                     +G     GP G  G+ G PGPPG  GLQGVPG  G+
Sbjct: 873  PGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGL 932

Query: 510  TGKPGVPGKEAS----EQRIRELCGGMISEQ--------------------------IAQ 539
             G+PG+  +  S    +  ++ +CG  +  Q                           AQ
Sbjct: 933  PGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ 992

Query: 540  LAAHLRKPLA-----------PGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGP--- 585
                L +P A           PG +G PG  GPPG PG  G  G PG RG PG  GP   
Sbjct: 993  CFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGP 1052

Query: 586  ------------------------TGELGDPGPRGN---------------QGDRGDKGA 606
                                    TG+ G+PGP G                +G+RG  G+
Sbjct: 1053 PGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGS 1112

Query: 607  AG----------AGLDGPEGDQGPQGPQGVPGTSKD----GQDGAPGEPGPPGDPGLPGA 652
            AG           GL GP G  GP+G +G  G S +    G  G PG PGPPG PG PG 
Sbjct: 1113 AGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGK 1172

Query: 653  IGAQGTPG 660
            +G+ G PG
Sbjct: 1173 VGSPGPPG 1180



 Score =  427 bits (1099), Expect = e-119
 Identities = 263/612 (42%), Positives = 295/612 (48%), Gaps = 92/612 (15%)

Query: 7    CAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA 66
            CA   L L       A G    G PG  G PG PG PG  G  GE GPPG+ G PGP G 
Sbjct: 990  CAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGP 1049

Query: 67   PGKPGKPGEAGLPGLPGVD------GLTGRDGPPGPKGAPGERGSLGPPGPPGL------ 114
             G PG PG  G PGLPG+       GLTG  G PGP G PG  G+ GPPG PG+      
Sbjct: 1050 IGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGY 1109

Query: 115  ----GGKGLPGPPGEAGVSGPPGGIGLRGPPGP---------SGLPGLPGPPGPPGPPGH 161
                G KG PGPPG  G+ GPPG  G RG  GP          G  G PG PGPPGPPG 
Sbjct: 1110 TGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGF 1169

Query: 162  PGVL----------PEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKG 211
            PG +           +G+  ++ PS   PG PGPPG PG +GP G  G  G+ GK G +G
Sbjct: 1170 PGKVGSPGPPGPQAEKGSEGIRGPSGL-PGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRG 1228

Query: 212  DPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERG 271
            DPGP GP GL G  G +G  G  GLPGP G  G  GP G  G PG  G PG  G +G  G
Sbjct: 1229 DPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPG 1288

Query: 272  PEGFRGPKGDLGRPGPKGTPGVA-----GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGA 326
            P G  GP G  G+PGP G   V      G +GE G+ G  GQ G PG  G  GE G +GA
Sbjct: 1289 PPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGA 1348

Query: 327  PGEKGPNGLPGL---PGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH 383
             G++GP G  G    PG  G  G  G++G+AGE G AG  G PG  G  G  G  G AG 
Sbjct: 1349 AGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGE 1408

Query: 384  RGSAGALGPQGPPGAPGVRGFQGQ------------------------------------ 407
            RG  GA GP G PG PGV G  G                                     
Sbjct: 1409 RGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEM 1468

Query: 408  ---KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGP 464
                G  G PG  G  G  G  G  G  G  G +G QG+ G  GLPG KGE G  G+   
Sbjct: 1469 AAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGI--- 1525

Query: 465  KGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQR 524
             G +G  G  GP G QGP G     G  G  GP+G QG+PG+PG  G  G PGK A    
Sbjct: 1526 -GIAGENGLPGPPGPQGPPG----YGKMGATGPMGQQGIPGIPGPPGPMGQPGK-AGHCN 1579

Query: 525  IRELCGGMISEQ 536
              +  G M  EQ
Sbjct: 1580 PSDCFGAMPMEQ 1591



 Score =  384 bits (985), Expect = e-106
 Identities = 268/666 (40%), Positives = 312/666 (46%), Gaps = 138/666 (20%)

Query: 60  PPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGS----LGPPGPPGL- 114
           P GPKG     GK GE GLPG            PPG KG  G RG+    + P  P    
Sbjct: 332 PSGPKG-----GK-GERGLPG------------PPGSKGEKGARGNDCVRISPDAPLQCA 373

Query: 115 -GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQ 173
            G KG  G  G  G SG PG  G +G  G  G  G+ G PG PG  G PG          
Sbjct: 374 EGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPG---------- 423

Query: 174 CPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGL 233
              IC  GP G  G PGF GP G  GE G  G       PGPPG  GLPG+ G  G    
Sbjct: 424 --EICVIGPKGQKGDPGFVGPEGLAGEPGPPGL------PGPPG-IGLPGTPGDPG---- 470

Query: 234 RGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERG---------PEGFRGPKGDLGR 284
               GP GP GD+G  G  G  G  G PGK G +GE+G         PEGF+   G  G+
Sbjct: 471 ----GPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGK 526

Query: 285 PGPKGTPGVAGPS-GEPGMPGKDGQNGVPGLD-----GQKGEAGRNGAPGEKGPN--GLP 336
           PGPKG PG   P+ G+PG+ G  G+ G P L      G +      GA G+ G    GLP
Sbjct: 527 PGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLP 586

Query: 337 GLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPP 396
           GLPGRAG  G KGE+G  GE G AG  G PG  G AG+ G +GE      A +    G  
Sbjct: 587 GLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDV 646

Query: 397 GAPGVRGFQGQKGSMGDP--GLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKG 454
               + G  G+KG  G P  GLPG QG  G+ G +G  G AG  GD G  G+ G PG  G
Sbjct: 647 RVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSG 706

Query: 455 ELGPSGLVGPKGE------------------SGSRGELGPKGTQGPNGTSGVQGVPGPPG 496
           E G  G  GPKGE                  +G  G+ GPKG QGP G  G  G PG PG
Sbjct: 707 EPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPG 765

Query: 497 PLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRP 556
             G+QG PG+ G+ G+PG PG+            G   E              PG+ G P
Sbjct: 766 LPGVQGPPGLKGVQGEPGPPGRGVQ---------GPQGE--------------PGAPGLP 802

Query: 557 GPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDP-----GPRGNQGDRGDKGAAGAGL 611
           G  G PGP GPPG  G  GA+G PG +G TG +G P     GP G  G +G       GL
Sbjct: 803 GIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQ-----TGL 857

Query: 612 DGPEGDQGPQGPQGVPGTSK---------DGQDGAPG-------EPGPPGDPGLPGAIGA 655
            G  G++GP+G +G PG             G  GAPG       +PGP G PG+PG  G 
Sbjct: 858 RGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGP 917

Query: 656 QGTPGI 661
            G PG+
Sbjct: 918 PGVPGL 923



 Score =  358 bits (919), Expect = 9e-99
 Identities = 220/497 (44%), Positives = 242/497 (48%), Gaps = 44/497 (8%)

Query: 4    PRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGP 63
            P A  P  L  + GE      A   G PGPPG  G PG PG  G  GE GP G  G  G 
Sbjct: 1092 PGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGD 1151

Query: 64   KGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG-LGGKGLPGP 122
            +G  G+PG PG  G PG PG  G  G  GP   KG+ G RG  G PG PG  G  G+ GP
Sbjct: 1152 QGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGP 1211

Query: 123  PGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGP 182
             G  G+ G  G  GLRG PGP+G PGL GPPG  G  GHPG LP    D        PGP
Sbjct: 1212 AGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPG-LPGPKGDCG-----KPGP 1265

Query: 183  PGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGP---PGPAGLPGSVGLQGPRGLRGLPGP 239
            PG  G PG +G  G  G QG  G  G  G PGP   PGPAG+  +VGL+G RG  G  G 
Sbjct: 1266 PGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGI-SAVGLKGDRGATGERGL 1324

Query: 240  LGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGE 299
             G PG  GP G  GPPG PG  G AG  G  G +GF GP G  G PG  G  G AG  G 
Sbjct: 1325 AGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGR 1384

Query: 300  PGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGE--- 356
             GMPG  G++G  G  G  G AG  G PG  GP+G PGLPG  GS G+            
Sbjct: 1385 AGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIR 1444

Query: 357  ---------------------LGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP 395
                                 +  A   G PG PG  G PG  G  G  G  G +G +G 
Sbjct: 1445 QEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGR 1504

Query: 396  PGAPGVRGFQGQKGSMGD--------PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSD 447
             G PGVRG  G KG  GD         GLPGP G +G  G  G  GA GP G QGI G  
Sbjct: 1505 QGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPG-YGKMGATGPMGQQGIPGIP 1563

Query: 448  GLPGDKGELGPSGLVGP 464
            G PG  G+ G +G   P
Sbjct: 1564 GPPGPMGQPGKAGHCNP 1580



 Score =  272 bits (695), Expect = 9e-73
 Identities = 208/545 (38%), Positives = 247/545 (45%), Gaps = 73/545 (13%)

Query: 178 CPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLP 237
           CPP   G         P+G KG     GK GE+G PGPPG  G  G+ G    R     P
Sbjct: 316 CPPCVHGARDSNVTLAPSGPKG-----GK-GERGLPGPPGSKGEKGARGNDCVRISPDAP 369

Query: 238 GPL--GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAG 295
                GP G++G  G  GP G+PG+ G+ G +GE+G  G +G  G  GR G  G   V G
Sbjct: 370 LQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIG 429

Query: 296 PSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNG--LPGLPGRAGSK-GEKGERG 352
           P G         Q G PG  G +G AG  G PG  GP G  LPG PG  G   G KG++G
Sbjct: 430 PKG---------QKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKG 480

Query: 353 RAGELGEAGPSGEPGVPGDAGMPGE---------RGEAGHRGSAGALGPQGPPGAP---- 399
            +G  G+ GP G+PG PG  G  G+          G     G  G  GP+G PG P    
Sbjct: 481 SSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPAR 540

Query: 400 GVRGFQGQKGSMGDPGLP-----GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKG 454
           G  G QG KG  G+P L      G Q L    G  G  G+ G  G  G+ G  G+PG KG
Sbjct: 541 GDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG-FGLPGLPGRAGVPGLKG 599

Query: 455 ELGPSGLVGPKGESGSRGELGPKGTQGPNGT------------SGVQGVPGPPGPLGLQG 502
           E G  G  GP G  G  G +GP G +G  G              G   V   PGP G +G
Sbjct: 600 EKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKG 659

Query: 503 VPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPP 562
            PG PG  G PG  GK A E+ ++   G          A +   P  PG+ GRPG +G P
Sbjct: 660 EPGPPGF-GLPGKQGK-AGERGLKGQKGD---------AGNPGDPGTPGTTGRPGLSGEP 708

Query: 563 GPPGPPGSIGHPG--ARGPPGYRGPT----GELGDPGPRGNQGDRG--DKGAAGA-GLDG 613
           G  GP G  G  G      P  +G      G  G PGP+G QG  G    G  G  GL G
Sbjct: 709 GVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPG 768

Query: 614 PEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGA--V 671
            +G  G +G QG PG    G  G  GEPG PG PG+ G  G +G PG       QG+  V
Sbjct: 769 VQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGV 828

Query: 672 LGGVG 676
            G  G
Sbjct: 829 KGATG 833



 Score =  265 bits (677), Expect = 1e-70
 Identities = 199/547 (36%), Positives = 242/547 (44%), Gaps = 124/547 (22%)

Query: 232 GLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGE-----------RGPEGFRGPKG 280
           G R     L P G +G  G RG PG PG+ G+ G RG            +  EG +G KG
Sbjct: 322 GARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKG 381

Query: 281 DLGRPGPKGTPGVAGPSGE------------PGMPGKD------------GQNGVPGLDG 316
           + G  GP G PG  G  G+            PG PG+D            GQ G PG  G
Sbjct: 382 ESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVG 441

Query: 317 QKGEAGRNGAPGEKGPN--GLPGLPG-RAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373
            +G AG  G PG  GP   GLPG PG   G  G KG++G +G  G+ GP G+PG PG  G
Sbjct: 442 PEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKG 501

Query: 374 MPGE---------RGEAGHRGSAGALGPQGPP-------GAPGVRGFQGQK--------- 408
             G+          G     G  G  GP+G P       G PG++G +G+K         
Sbjct: 502 EKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSS 561

Query: 409 -----------GSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELG 457
                      G+ GD G PG  GL G  G  G  G  G KG+ G AG  G PG  G +G
Sbjct: 562 VVGAQHLVSSTGASGDVGSPG-FGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVG 620

Query: 458 PSGLVGPKGE------------------------SGSRGELGP--------KGTQGPNGT 485
           P+G+ G KGE                        SG +GE GP        +G  G  G 
Sbjct: 621 PAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGL 680

Query: 486 SGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQ--IAQLAAH 543
            G +G  G PG  G  G  G PG++G+PGV G    +    + C    S Q  +  +A  
Sbjct: 681 KGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAG- 739

Query: 544 LRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGD 603
             +P  PG  G  GP G  G PG PG  G PG +GPPG +G  GE G PG RG QG +G+
Sbjct: 740 --RPGQPGPKGEQGPEG-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGE 795

Query: 604 KGAAG----AGLDGPEGDQGPQGPQGVPGT----SKDGQDGAPGE--PGPPGDPGLPGAI 653
            GA G     GL GP G  GP G +G  G+       G  G PG    GPPG  G  G  
Sbjct: 796 PGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQT 855

Query: 654 GAQGTPG 660
           G +GTPG
Sbjct: 856 GLRGTPG 862



 Score =  171 bits (434), Expect = 2e-42
 Identities = 139/436 (31%), Positives = 169/436 (38%), Gaps = 103/436 (23%)

Query: 338 LPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPG 397
           L GR   K E+G +       +  P   P V G          +G +G  G  G  GPPG
Sbjct: 293 LTGRISQKAERGAKVHQETAADECP---PCVHGARDSNVTLAPSGPKGGKGERGLPGPPG 349

Query: 398 APGVRG-----------------FQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGD 440
           + G +G                  +G KG  G+ G  GP GL G  G++   G  G KGD
Sbjct: 350 SKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEK---GQKGEKGD 406

Query: 441 QGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP-------- 492
            GI G  G PG  G  G   ++GPKG+ G  G +GP+G  G  G  G+ G P        
Sbjct: 407 GGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTP 466

Query: 493 ----GPPGP---LGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLR 545
               GPPGP    G  G+PG  G  GKPG PG +  +    E+C   + E          
Sbjct: 467 GDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVC-PTLPEGFQNFVGLPG 525

Query: 546 KPLAPGSIGRPGPA-GPP----------------------------------------GP 564
           KP   G  G P PA G P                                        G 
Sbjct: 526 KPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGL 585

Query: 565 PGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG---------------- 608
           PG PG  G PG +G  G  G  G  G PGP G  G  G KGA G                
Sbjct: 586 PGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGD 645

Query: 609 ---AGLDGPEGDQGPQGPQ--GVPG-TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662
                L GP G++G  GP   G+PG   K G+ G  G+ G  G+PG PG  G  G PG+ 
Sbjct: 646 VRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLS 705

Query: 663 DTSACQGAVLGGVGEK 678
                QG   G  GEK
Sbjct: 706 GEPGVQGPA-GPKGEK 720



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 51/158 (32%), Positives = 70/158 (44%), Gaps = 23/158 (14%)

Query: 534 SEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPG 593
           SE  AQL   + +    G+      A    PP   G+        P G +G  GE G PG
Sbjct: 287 SEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPG 346

Query: 594 PRGNQGDRGDKG------------AAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEP 641
           P G++G++G +G                G  G +G+ G  GP G+PG++  G+ G  GE 
Sbjct: 347 PPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGST--GEKGQKGEK 404

Query: 642 GPPGDPGLPGAIGAQGTPG-ICDTSACQGAVLGGVGEK 678
           G  G  G+PG  G  G PG IC        V+G  G+K
Sbjct: 405 GDGGIKGVPGKPGRDGRPGEIC--------VIGPKGQK 434


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  511 bits (1315), Expect = e-144
 Identities = 326/765 (42%), Positives = 369/765 (48%), Gaps = 128/765 (16%)

Query: 19   LLAAAGAQRV-GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAG 77
            L  A GA  + G+ G PG PGP G PG  G  G  G  GL G PGP G+ G+ G  GE G
Sbjct: 305  LTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPG 364

Query: 78   LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL----GGKGLPGPPGEAGVSGPPG 133
              G  G  G +G +G  GP    GE GS GPPGPPGL    G +GLPG  G AGV GPPG
Sbjct: 365  SAGPQGPPGPSGEEGKRGPN---GEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPG 421

Query: 134  G------IGLRGPPGPSGLPGLPGPPGPPGPPGHPG----------------------VL 165
                    G+RGP G +G PG PG  GP G PG PG                      + 
Sbjct: 422  SRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIG 481

Query: 166  PEGAT----DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGL 221
            P GA     ++  P   P GP G PG  G KG  G  G +G  G DG  G  GPPGP G+
Sbjct: 482  PAGARGEPGNIGFPG--PKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGV 539

Query: 222  PGSVGLQ---GPRGLRGLPGPLGP------------------PGDRGPIGFRGPPGIPGA 260
             G  G Q   GP G +GLPGP GP                  PG  GP G RGPPG  GA
Sbjct: 540  QGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGA 599

Query: 261  PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGE 320
             G  G  G RGP G  GP G+ G PG  G  G AGPSG  G+PG+ G  G+PG  G+KGE
Sbjct: 600  AGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGE 659

Query: 321  AGRNGA---PGEKGPNGLP---GLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGD--- 371
             G  G    PG  G  G P   G PG AG+ G++GE G AG  G AGP G PG  G+   
Sbjct: 660  PGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGP 719

Query: 372  ------------AGMPGERGEAGHR---------------GSAGALGPQGPPGAPGVRGF 404
                        AG PG +GE G +               G+AG  GP GPPG  G RG 
Sbjct: 720  AGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGD 779

Query: 405  QGQKGSMGDPGL------PGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGP 458
             G  G  G PG       PGP G+ G  G  GP G  G +G +G  G  G  G+ G +GP
Sbjct: 780  GGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGP 839

Query: 459  SGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK 518
             G  G KG SG  G  GP GT GP G  G  G+ G PG  G +G+PGV G  G+PG P  
Sbjct: 840  PGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPG-PLG 898

Query: 519  EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARG 578
             A     R   G + S  +           APG  GR G  G  GPPG  G  GH G RG
Sbjct: 899  IAGPPGARGPPGAVGSPGVNG---------APGEAGRDGNPGNDGPPGRDGQPGHKGERG 949

Query: 579  PPGYRGPTGELGDPGPR------GNQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPGTSK 631
             PG  GP G  G PGP       G  G+RG+ G +G  G  G  G +GP GPQG+     
Sbjct: 950  YPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGI----- 1004

Query: 632  DGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVG 676
             G  G PGE GP G PGL G  G QG PGI      QGA  G VG
Sbjct: 1005 RGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAP-GSVG 1048



 Score =  501 bits (1289), Expect = e-141
 Identities = 312/725 (43%), Positives = 355/725 (48%), Gaps = 102/725 (14%)

Query: 24  GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA---------------PG 68
           G   +GL GP GPPG  G PG  G  G AG PG PG  GP GA               PG
Sbjct: 89  GPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPG 148

Query: 69  KPGKPGEAGL------------PGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG--- 113
           KPG+PGE G+            PGLPG  G+ G +G  G KG PG  G  G PG PG   
Sbjct: 149 KPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENG 208

Query: 114 ----LGGKGLP------GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPG 163
                G +GLP      G PG AG  G  G +G  GP GP G  G PG PG PGP G  G
Sbjct: 209 TPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIG 268

Query: 164 VL----PEGAT----DLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGP 215
            +    P G      ++  P +   GP GPPG PG  G TG K   G  G  G  G PG 
Sbjct: 269 AVGNAGPAGPAGPRGEVGLPGL--SGPVGPPGNPGANGLTGAK---GAAGLPGVAGAPGL 323

Query: 216 PGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGF 275
           PGP G+PG VG  G  G RGL G  GP G +G  G +G PG  G  G  G  GE   EG 
Sbjct: 324 PGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGE---EGK 380

Query: 276 RGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV------------PGLDGQKGEAGR 323
           RGP G+ G  GP G PG+ G  G  G+PG DG+ GV             G+ G  G+AGR
Sbjct: 381 RGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGR 440

Query: 324 NGAPGEKGPNGLPGLPGRAGSKGEKGE------RGRAGELGEAGPSGEP---------GV 368
            G PG  GP GLPG PG  G  G++G        GR G +G AG  GEP         G 
Sbjct: 441 PGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGP 500

Query: 369 PGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGD 428
            GD G  G++G AG  G+ GA GP G  GA G  G QG +G  G+ G PGP G +G  G 
Sbjct: 501 TGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGP 560

Query: 429 RGPGGAAGPKGDQGIAGSDGLP---GDKGELGP---SGLVGPKGESGSRGELGPKGTQGP 482
            GP G  G  G++G+ G  GLP   G +GE GP   SG  GP G  GSRG  GP G  G 
Sbjct: 561 SGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGN 620

Query: 483 NGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG--GMISEQIAQL 540
            G  GV G  G  GP G  G+PG  G  G PG  G E  E  +R   G  G    + A  
Sbjct: 621 KGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKG-EKGEPGLRGEIGNPGRDGARGAPG 679

Query: 541 AAHLRKPLAP----GSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRG 596
           A     P       G  G  GPAGP GP G PG  G  G  GP G+ GP G  G PG +G
Sbjct: 680 AVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKG 739

Query: 597 NQGDRGDKGAAG-AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGA 655
            +G +G KG  G  G  GP G  GP GP G PG +     G+ G+ GPPG  G PGA G 
Sbjct: 740 ERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPA-----GSRGDGGPPGMTGFPGAAGR 794

Query: 656 QGTPG 660
            G PG
Sbjct: 795 TGPPG 799



 Score =  484 bits (1247), Expect = e-137
 Identities = 300/684 (43%), Positives = 335/684 (48%), Gaps = 114/684 (16%)

Query: 29   GLPGPPGPPGPPGKPGQ---DGIDGEAGPPG------------LPGPPGPKGAPGKPGKP 73
            GLPG PG  GP GK G     GIDG  GP G             PGP GP G PGK G  
Sbjct: 451  GLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDK 510

Query: 74   GEAGLPGL---PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK------------- 117
            G AGL G    PG DG  G  GPPGP+G  G +G  GPPGPPG  G              
Sbjct: 511  GHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKP 570

Query: 118  ---------GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEG 168
                     GLPGP G  G  GPPG  G  GP GP G  G  GPPGP G  G PGV+  G
Sbjct: 571  GERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV--G 628

Query: 169  ATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQ 228
            A     PS    GP G PG  G  G  G KGE+GE G  GE G+PG  G  G PG+VG  
Sbjct: 629  AVGTAGPS----GPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAP 684

Query: 229  GP------RGLRGLPGPLGP------PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFR 276
            GP      RG  G  GP GP      PG+RG +G  GP G  G  G AG  G +G  G +
Sbjct: 685  GPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAK 744

Query: 277  GPKGD---LGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPN 333
            GPKG+   +G  GP G  G AGP+G PG  G  G  G PG+ G  G AGR G PG  G +
Sbjct: 745  GPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS 804

Query: 334  GLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQ 393
            G PG PG AG +G +G RG  G +G  G  G  G PG AG  G  GEAG  G  G  GPQ
Sbjct: 805  GPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQ 864

Query: 394  GPPGAPGVRGFQGQKGSMGDPGL------PGPQGLRGDVGDRGPGGAAGP---------- 437
            G  GAPG+ G  G +G  G PG+      PGP G+ G  G RGP GA G           
Sbjct: 865  GLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEA 924

Query: 438  -----KGDQGIAGSDGLPGDKGEL---------------GPSGLVGPKGESGSRGELGPK 477
                  G+ G  G DG PG KGE                GP G VGP G+ G+RGE GP 
Sbjct: 925  GRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPS 984

Query: 478  GTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQI 537
            G  GP   +G  G  GP GP G++G  G PG  G  G+PG          L G    + +
Sbjct: 985  GPVGP---AGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPG----------LKGHNGLQGL 1031

Query: 538  AQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGS---IGHPGARGPPGYRGPTGELGDPGP 594
              +A H     APGS+G  GP GP GP GP G     GHPG  GP G RGP G  G  GP
Sbjct: 1032 PGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGP 1091

Query: 595  RGNQGDRGDKGAAGAGLD-GPEGD 617
             G  G  G  G +G G D G +GD
Sbjct: 1092 PGPPGPPGPPGVSGGGYDFGYDGD 1115



 Score =  476 bits (1225), Expect = e-134
 Identities = 312/731 (42%), Positives = 351/731 (48%), Gaps = 89/731 (12%)

Query: 13  LLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK 72
           LLLL   L  A  Q   L       GP G  G  G  G  GPPG  G  GP G PG PG 
Sbjct: 10  LLLLAVTLCLATCQ--SLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGP 67

Query: 73  PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGG----KGLPGPPGEAGV 128
           PG  GL G         +    G    PG  G +GP GPPG  G    +G  GP GE G 
Sbjct: 68  PGPPGLGG-----NFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGE 122

Query: 129 SGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICPPGPPGPPG 187
            G  G  G RGP GP G  G  G PG PG PG  GV+ P+GA          PG PG PG
Sbjct: 123 PGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGF-------PGTPGLPG 175

Query: 188 MPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS------------VGLQGPRGLRG 235
             G +G  G  G +G+ G  G KG+PG PG  G PG             VG  GP G RG
Sbjct: 176 FKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARG 235

Query: 236 LPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRG---ERGPEGFRGPKGDLGRPG------ 286
             G +GP G  GPIG  GPPG PGAPG  G+ G     GP G  GP+G++G PG      
Sbjct: 236 SDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVG 295

Query: 287 PKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKG 346
           P G PG  G +G  G  G  G  G PGL G +G  G  GA G  G  GL G PG AGSKG
Sbjct: 296 PPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKG 355

Query: 347 E---KGERGRAGELGEAGPSGE---------------PGVPGDAGMPGERGEAGHRGSAG 388
           E   KGE G AG  G  GPSGE               PG PG  G PG RG  G  G AG
Sbjct: 356 ESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAG 415

Query: 389 ALGPQGPPGAPG---VRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGI-- 443
            +GP G  GA G   VRG  G  G  G+PGL GP+GL G  G+ GP G  GP G  GI  
Sbjct: 416 VMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDG 475

Query: 444 -------AGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPG 496
                  AG+ G PG+ G  GP G  G  G++G +G  G  G +G  G  G  G  GPPG
Sbjct: 476 RPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPG 535

Query: 497 PLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRP 556
           P G+QG  G  G  G PG  G         E+  G   E+      H       G  G P
Sbjct: 536 PQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEV--GKPGER----GLH-------GEFGLP 582

Query: 557 GPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPE 615
           GPAGP G  GPPG  G  G  GP G RGP+   G PGP GN+G+ G  GA G AG  GP 
Sbjct: 583 GPAGPRGERGPPGESGAAGPTGPIGSRGPS---GPPGPDGNKGEPGVVGAVGTAGPSGPS 639

Query: 616 GDQGPQGPQGVP-GTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG-AVLG 673
           G  G +G  G+P G  + G+ G  GE G PG  G  GA GA G PG    +  +G A   
Sbjct: 640 GLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAA 699

Query: 674 GVGEKSGSRSS 684
           G    +G R S
Sbjct: 700 GPAGPAGPRGS 710



 Score =  399 bits (1026), Expect = e-111
 Identities = 231/498 (46%), Positives = 258/498 (51%), Gaps = 36/498 (7%)

Query: 28   VGLPGPPGPPGPPGKPGQDGIDG---EAGPPGL------PGPPGPKGAPGKPGKPGEAGL 78
            VG  GP GP G PG+ G  GI G   E G PGL      PG  G +GAPG  G PG AG 
Sbjct: 630  VGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGA 689

Query: 79   PGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL----GGKGLPGPPGEAGVSGPPGG 134
             G  G  G  G  GP GP+G+PGERG +GP GP G     G  G PG  GE G  GP G 
Sbjct: 690  TGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGE 749

Query: 135  IGLRGPPGPSGLPGLPGPPGPPGPPGHPG-VLPEGATDLQCPSICPPGPPGPPGMPGFKG 193
             G+ GP GP G  G  GP GPPGP G  G   P G T         PG  G  G PG  G
Sbjct: 750  NGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGF-------PGAAGRTGPPGPSG 802

Query: 194  PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRG 253
             +G  G  G  GK+G +G  G  GP G  G VG  GP G  G  GP G  G  GP G  G
Sbjct: 803  ISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPG 862

Query: 254  PPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPG 313
            P G+ GAPG  G  G RG  G  G  G +G PGP G  G  G  G PG  G  G NG PG
Sbjct: 863  PQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPG 922

Query: 314  LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373
                  EAGR+G PG  GP G  G PG  G +G  G  G  G  G  GP G  G  G  G
Sbjct: 923  ------EAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHG 976

Query: 374  MPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGG 433
              GE G +G  G AGA+GP+GP G  G+RG +G+ G  G  GLP   GL+G  G +G  G
Sbjct: 977  NRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLP---GLKGHNGLQGLPG 1033

Query: 434  AAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPG 493
             AG  GDQG  GS G  G +G  GPSG  G  G +G  G +GP G +GP G  G  G PG
Sbjct: 1034 IAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPG 1093

Query: 494  PPGPLGLQGVPGVPGITG 511
            PPGP      PG PG++G
Sbjct: 1094 PPGP------PGPPGVSG 1105



 Score =  277 bits (709), Expect = 2e-74
 Identities = 167/415 (40%), Positives = 193/415 (46%), Gaps = 45/415 (10%)

Query: 22   AAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGL 81
            A  A   G PG  G  G  G  G++G+ G  GP G  GP GP G PG  G  G+ G PG+
Sbjct: 726  AGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGM 785

Query: 82   PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL----GGKGLPGPPGEAGVSGPPGGIGL 137
             G  G  GR GPPGP G  G  G  GP G  GL    G +G  G  GE G  GPPG  G 
Sbjct: 786  TGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGE 845

Query: 138  RGPPGPSGLPGLPGPPGPPGPPGHPGVL--PEGATDLQCPSIC-------------PPGP 182
            +GP G +G  G PG PGP G  G PG+L  P    +   P +              PPG 
Sbjct: 846  KGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGA 905

Query: 183  PGPPGM---PGFKGPTGYKGEQGEVGKDG------------EKGDPGPPGPAGLPGSVGL 227
             GPPG    PG  G  G  G  G  G DG            E+G PG  GP    G+ G 
Sbjct: 906  RGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPV---GAAGA 962

Query: 228  QGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGP 287
             GP       GP+GP G  G  G  GP G  G  G  G RG  GP+G RG KG+ G  GP
Sbjct: 963  PGPH------GPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGP 1016

Query: 288  KGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGE 347
            +G PG+ G +G  G+PG  G +G  G  G  G AG  G  G  GP G  G  G  G+ G 
Sbjct: 1017 RGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGP 1076

Query: 348  KGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVR 402
             G RG  G  G AGP G PG PG  G+ G   + G+ G         P  AP +R
Sbjct: 1077 AGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGD--FYRADQPRSAPSLR 1129



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 37/91 (40%), Positives = 43/91 (47%), Gaps = 4/91 (4%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEA 76
            G+  A       G  GP GP GP GK G+ G  G  GP G+ GP G +G  G PG PG  
Sbjct: 1039 GDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP 1098

Query: 77   GLPGLPGVDGLTGRDG----PPGPKGAPGER 103
            G PG+ G     G DG       P+ AP  R
Sbjct: 1099 GPPGVSGGGYDFGYDGDFYRADQPRSAPSLR 1129


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  510 bits (1313), Expect = e-144
 Identities = 330/775 (42%), Positives = 385/775 (49%), Gaps = 145/775 (18%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGP---PGLPGPPGPKGAPGKPG-KPGEA-------- 76
            GLPGPPG PG PG PG  G  G  GP   PGLPGPPG KG  G PG  PG+A        
Sbjct: 634  GLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDM 693

Query: 77   GLPGL---PGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL----GGKGLPGPPGEAGVS 129
            GLPGL   PG  G  G  G PGP G PGE+G  GP G PG     G +GLPGP G+ G  
Sbjct: 694  GLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPK 753

Query: 130  GP------PGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPE---GATDLQCPSICPP 180
            G       PG  GL G  G  GLPG+PG  G  G PG PGV  E      D     +  P
Sbjct: 754  GSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLP 813

Query: 181  GPPGPPGM---------PGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPR 231
            GPPG PG+          G+ GP G KG  G VG+ G KGD G  G  G+ G  G QG +
Sbjct: 814  GPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDK 873

Query: 232  GLRGL---------PGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDL 282
            G +GL         PGPLG  GD+G IGF GPPG  G PG  G  G+ GPEG +G  G  
Sbjct: 874  GSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGAR 933

Query: 283  GRPGPK---GTPGVAGPSGEPGMPGKDGQ------NGVPGLDGQKGEAGRNGAP---GEK 330
            G PGP+   G  G  GP G PG PG +GQ       G PGLDG KGE G  G P   GE+
Sbjct: 934  GLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQ 993

Query: 331  GPNGLPGLPGRAGSKGEKGERGRAGELGEAGPS---GEPGVPGDAGMPGE---------- 377
            G  G  GL G  G  GEKG+RG  G  G  GP    G PG+PG  G PGE          
Sbjct: 994  GFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSR 1053

Query: 378  --------------------RGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGD---P 414
                                 GE G RG  G  GPQG PG PG +G  G++G +G    P
Sbjct: 1054 GPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFP 1113

Query: 415  GLPGP------QGLRGDVGDR------GPGGAAGPKGDQGIAGSDGLPGD---KGELGPS 459
            G+PGP      +GL G+ G +      GP G  GPKG  G  G  GLPG+   KG+LGP 
Sbjct: 1114 GIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPL 1173

Query: 460  GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGP------------LGLQGVPGVP 507
            G  G +G  G RGE G +G  GP G  G++G  G PGP            +G  G PG P
Sbjct: 1174 GTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPP 1233

Query: 508  GITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGP------AGP 561
            G+TG  G  GK + +Q  +   G   ++        +  P  PG  G PGP       GP
Sbjct: 1234 GVTGVRGPEGK-SGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGP 1292

Query: 562  PGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGP- 620
             G PG  G+ G PG  G  G++G  G LG PGP+G +G++G+ G A  G  GP GD+GP 
Sbjct: 1293 TGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKA-EGPPGPPGDRGPV 1351

Query: 621  --QGPQGVPG-------------TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
              +G +G PG               K GQ G PG PGP G PG  G+ GA+G  G
Sbjct: 1352 GDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKG 1406



 Score =  495 bits (1274), Expect = e-140
 Identities = 304/715 (42%), Positives = 347/715 (48%), Gaps = 76/715 (10%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPG---------EAGLP 79
            GLPG PG  G  G PG  G+ GE GPPGL G PG  G PG PG PG           G P
Sbjct: 775  GLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYP 834

Query: 80   GLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL----GGKGLPGPPGEAGVSGP---- 131
            G  G+ GL G  G PG KG  GE+G  G  G PG     G +GLPG PG  G  GP    
Sbjct: 835  GPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKV 894

Query: 132  --PGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCP--SICPPG---PPG 184
               G IG  GPPGP G PG  GPPG  GP G  G    GA  L  P   + P G   P G
Sbjct: 895  GDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKG--KPGARGLPGPRGQLGPEGDEGPMG 952

Query: 185  PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPG------ 238
            PPG PG +G  G KG  G  G DG KG+PG PG  G  G  G  G  GL G PG      
Sbjct: 953  PPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKG 1012

Query: 239  ---PLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGP---KGDLGRPGPKGTPG 292
                +GPPG  GP G  G PG+PG  G  G+ G +GP G RGP   +G  GR GP+G  G
Sbjct: 1013 DRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDG 1072

Query: 293  VAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG 352
             AG  G  G+ G  G  G PG  GQ+G AG  G  G +G  G+PG  G  G+KG  GE G
Sbjct: 1073 PAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPG 1132

Query: 353  RAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMG 412
              G  G  GP GE G  G  G  GE G  G  G  G LGP G PG  G+ G +G+ G  G
Sbjct: 1133 PQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEG 1192

Query: 413  DPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRG 472
            D G  GP GL+GD GD GP G  G KG +G+ G DG PG  G  G  G  G  G+ G +G
Sbjct: 1193 DSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKG 1252

Query: 473  ELGPKGTQGPNGTSGVQGVPGPPGP------------LGLQGVPGVPGITGKPGVPGKEA 520
              G KG +G  G  G  GVPG PGP            LG  G PG  G  G+PG+ G + 
Sbjct: 1253 RTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDG 1312

Query: 521  SEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPP 580
             +  +  L       +  +     +    PG  G  GP G  G  G PG  G+PG  G  
Sbjct: 1313 HKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQ 1372

Query: 581  GYRGPTGELGD---PGPRGNQGDRGDKGAAG-------------------AGLDGPEGDQ 618
            G RG  G+ G    PGPRG  G +G KGA G                    GL GP G  
Sbjct: 1373 GLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVV 1432

Query: 619  GPQGPQGVPG----TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG 669
            G QG +G+ G      +DGQ G  GE G  GDPG  G  G +G PG+      QG
Sbjct: 1433 GRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQG 1487



 Score =  493 bits (1269), Expect = e-139
 Identities = 300/718 (41%), Positives = 362/718 (50%), Gaps = 103/718 (14%)

Query: 28   VGLPGPPGPPG------PPGKPGQDGIDGEAGPPGLPGPPG------------PKGAPGK 69
            +G PGPPGP G      PPG  G +G+ G+ G  GLPGP G            P GAPG 
Sbjct: 900  IGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGL 959

Query: 70   PGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLG---PPGPPGLGGK--------- 117
             G+PG  G PG PG+DG+ G  G PG  G  GE+G +G     G PG+ G+         
Sbjct: 960  EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGP 1019

Query: 118  -GLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCP 175
             G+PGP G  G  G PGG+G  G PGP G PG  GPPG  G  G  G   P+G    Q  
Sbjct: 1020 PGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQ-G 1078

Query: 176  SICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRG 235
            S    GPPGP G PG  G  G  GE+G +G    +G PG PGP+G PG+ GL G  G +G
Sbjct: 1079 SRGLKGPPGPQGRPGRPGQQGVAGERGHLGS---RGFPGIPGPSGPPGTKGLPGEPGPQG 1135

Query: 236  LPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAG 295
              GP+GPPG+ GP G  G  G PG PG+AG +G+ GP G  G +G +G+   +G PG+ G
Sbjct: 1136 PQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQ---RGEPGLEG 1192

Query: 296  PSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPG------RAGSKGEKG 349
             SG  G  G  G  G PG DG+ GE G+ G  GE GP G PG+ G      ++G +GEKG
Sbjct: 1193 DSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKG 1252

Query: 350  ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGA-------------------- 389
              G  G  G  G  GE GVPGD G PG  G  G RGS G                     
Sbjct: 1253 RTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDG 1312

Query: 390  ----LGPQGPPGAPGVRGFQGQKGSM-GDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIA 444
                +GP GPPG  G +G QG+ G   G PG PG +G  GD GDRG  G  G  G +G+ 
Sbjct: 1313 HKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQ 1372

Query: 445  GSDGLPGDKGELG---PSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQ 501
            G  G PG +G+ G   P G  GPKG  G+ G  G +G  G  G  GVQG+ G PGP G+ 
Sbjct: 1373 GLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVV 1432

Query: 502  GVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP 561
            G  G+ GI G  G+PG++           G   EQ              G  G PGP GP
Sbjct: 1433 GRQGLEGIAGPDGLPGRDGQ--------AGQQGEQ--------------GDDGDPGPMGP 1470

Query: 562  PGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGP 620
             G  G PG  G PGA+GPPG++G +G  G  GP G +G  G  G  G  G  G +G  G 
Sbjct: 1471 AGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGD 1530

Query: 621  QGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG--AVLGGVG 676
             G  G PG +     G  G  GPPGD G  G  G +G PG+       G   +LG  G
Sbjct: 1531 SGEMGFPGMA-----GLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSG 1583



 Score =  486 bits (1250), Expect = e-137
 Identities = 293/695 (42%), Positives = 352/695 (50%), Gaps = 104/695 (14%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP---------------------------- 60
            GL G PG  G PG+PG DG+ GE G PG PGP                            
Sbjct: 958  GLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMM 1017

Query: 61   -----PGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLG 115
                 PGPKG+ G PG PG  G PG PG  G  G  GPPG +GA G RG  GP GP G  
Sbjct: 1018 GPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQ 1077

Query: 116  G----KGLPGP------PGEAGVSGPPGGIGLRG---------PPGPSGLPGLPGPPGPP 156
            G    KG PGP      PG+ GV+G  G +G RG         PPG  GLPG PGP GP 
Sbjct: 1078 GSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQ 1137

Query: 157  GPPGHPGVL-PEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGE---KGD 212
            GP G PG + P+G       ++  PG PG  GM G  GP G  GEQG +G+ GE   +GD
Sbjct: 1138 GPIGPPGEMGPKGPPG----AVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGD 1193

Query: 213  PGPPGPAGL------PGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGD 266
             GP GP GL      PG  G  G +G  GL G  GPPG  G  G RGP G  G  G+ G 
Sbjct: 1194 SGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGR 1253

Query: 267  RGERGPEGFRGPKGDLG---------RPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQ 317
             G +G +G++G  G++G          PGPKG+ G  GP+G PG  G  G+ G+ G DG 
Sbjct: 1254 TGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGH 1313

Query: 318  KGEAGRNGAPGEKGPNGLPGLPGRA-GSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPG 376
            KG  G  G PG KG  G  G  G+A G  G  G+RG  G+ G+ G  G+PG PG  G+ G
Sbjct: 1314 KGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQG 1373

Query: 377  ERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAG 436
             RG+ G +G  G  GP+G PG  G +G +G KG  G  G PG +G++G  G  GP G  G
Sbjct: 1374 LRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433

Query: 437  PKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPG 496
             +G +GIAG DGLPG  G+       G +GE G  G+ GP G  G  G  GV G+PG  G
Sbjct: 1434 RQGLEGIAGPDGLPGRDGQ------AGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQG 1487

Query: 497  PLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRP 556
            P G +G  G+PG  G PG  G E           G+   Q             PGS G+P
Sbjct: 1488 PPGFKGESGLPGQLGPPGKRGTEGRT--------GLPGNQGE-----------PGSKGQP 1528

Query: 557  GPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPE 615
            G +G  G PG  G  G  G  G  G++G  G  G PG  G +G  G  G  G +GL GP+
Sbjct: 1529 GDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPK 1588

Query: 616  GDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLP 650
            GD+G +G  G+ G    G  G  G PGPPG PG P
Sbjct: 1589 GDKGSRGDWGLQGPR--GPPGPRGRPGPPGPPGGP 1621



 Score =  444 bits (1141), Expect = e-124
 Identities = 270/640 (42%), Positives = 318/640 (49%), Gaps = 102/640 (15%)

Query: 106  LGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL 165
            +GPPGP G    GLPGPPG  G+ G PG  G RGPPGP G PGLPGPPG  G  G PG+ 
Sbjct: 624  MGPPGPKG--DCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLS 681

Query: 166  PEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSV 225
            P  A D         G  G PG+ G  GP G KG +G  G  G  G+ G PGP G PG+ 
Sbjct: 682  PGKAHD------GAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAK 735

Query: 226  GLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDR------------------ 267
            G  G +GL   PGP+G PG +G  G+ G PG+ G PG  G+R                  
Sbjct: 736  GYPGRQGL---PGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFP 792

Query: 268  ---GERGPEGFRGPKGDLGRPGPKGTP------GVAGPSGEP---GMPGKDGQNGVPGLD 315
               GERGP G  G  G+LG PGP G P      GV GP G P   GM G  G  G PGL 
Sbjct: 793  GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLK 852

Query: 316  GQKGE------AGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVP 369
            G KGE      +G  G  G+KG  GLPG PG  G  G  G+ G  G +G  GP G  G P
Sbjct: 853  GDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFP 912

Query: 370  GDAGMPGERGEAGHRGSAGAL---------------GPQGPPGAPGVR------------ 402
            GD G PG+ G  G +G  GA                GP GPPGAPG+             
Sbjct: 913  GDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRP 972

Query: 403  GFQGQKGSMGDPGLPGP---QGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPS 459
            G  G KG  GDPG PGP   QG  G +G  G  G  G KGD+G+ G  G+PG KG +G  
Sbjct: 973  GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHP 1032

Query: 460  GLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGP------LGLQGVPGVPGITGKP 513
            G+ G  G  G  G  GP G++GP G  G +G  GP GP       G +G+ G PG  G+P
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092

Query: 514  GVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPP---------GP 564
            G PG    +Q +    G + S     +      P   G  G PGP GP          GP
Sbjct: 1093 GRPG----QQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148

Query: 565  PGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG----AGLDGPEGDQGP 620
             GPPG++G PG  G  G +G  G LG PG +G  G RG+ G  G     G DG +GD+G 
Sbjct: 1149 KGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGD 1208

Query: 621  QGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
             GP G  G  + GQ+G  GE GPPG PG+ G  G +G  G
Sbjct: 1209 PGPDGEHG--EKGQEGLMGEDGPPGPPGVTGVRGPEGKSG 1246



 Score =  418 bits (1074), Expect = e-116
 Identities = 236/512 (46%), Positives = 280/512 (54%), Gaps = 39/512 (7%)

Query: 29   GLPGPPGPPGP---PGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVD 85
            G+PGP GPPG    PG+PG  G  G  GPPG  GP GP GA G+PG PGEAG+ G  G  
Sbjct: 1114 GIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPL 1173

Query: 86   GLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPGPS 144
            G  G  G  G +G PG  G  GP GP GL G +G PGP GE G  G  G +G  GPPGP 
Sbjct: 1174 GTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPP 1233

Query: 145  GLPGLPGPPGPPGPPGHPGVL-PEGATDLQ--CPSICPPGPPGPPGMPGFKGPTGYKGEQ 201
            G+ G+ GP G  G  G  G    +GA   Q     +  PG PGPPG PG KG  G  G  
Sbjct: 1234 GVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPT 1293

Query: 202  GEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRG----------LPGPLGPPGDRGPIGF 251
            G  G+ G +G+PG  G  G  G VG  GP G +G            GP GPPGDRGP+G 
Sbjct: 1294 GAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGD 1353

Query: 252  RGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
            RG  G PG PG  G  G +G  G  G +G  G PGP+G PG  G  G  G  GK G+ G 
Sbjct: 1354 RGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGA 1413

Query: 312  PG---------LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGP 362
            PG         L G +G  GR G  G  GP+GLPG  G+AG +GE+G+ G  G +G AG 
Sbjct: 1414 PGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGK 1473

Query: 363  SGEPGVPG------------DAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGS 410
             G PGV G            ++G+PG+ G  G RG+ G  G  G  G PG +G  G  G 
Sbjct: 1474 RGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGE 1533

Query: 411  MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGS 470
            MG PG+ G  G +G  GD G  G  GP+G  G+ G +G+ G  G LGPSGL GPKG+ GS
Sbjct: 1534 MGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGS 1593

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPP-GPLGLQ 501
            RG+ G +G +GP G  G  G PGPP GP+ LQ
Sbjct: 1594 RGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQ 1625



 Score =  350 bits (897), Expect = 3e-96
 Identities = 269/801 (33%), Positives = 320/801 (39%), Gaps = 177/801 (22%)

Query: 33   PPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDG 92
            P   P P  K         A P     PP  +  P +  +P E  +   PG+     R  
Sbjct: 381  PIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMP----RPP 436

Query: 93   PPGPKGAPGERGSLGPPGPPGLGGKGL----PGPPGEAGVS--GPPGGIGLRGPPGPS-G 145
            PP  +  P    S   P P     +         P  A  S   PP    L   P P+ G
Sbjct: 437  PPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPG 496

Query: 146  LPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK--GPTGYKGE--- 200
                  PP    PP      P  A  +  P   P G   P G    K  GP     +   
Sbjct: 497  STRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVP 556

Query: 201  --QGEVGKDGEKGD------PGPPGPA--------------------------------- 219
               G+  +D    D      P  P P+                                 
Sbjct: 557  LRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAG 616

Query: 220  --------GLPG---SVGLQGPRGLRGLP------GPLGPPGDRGPIGFRGPP------- 255
                    G PG     GL GP GL GLP      GP GPPG  G  G  GPP       
Sbjct: 617  STPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKG 676

Query: 256  -----------------GIPGAPGKAGDRGERGPEGFRGP---KGDLGRPGPKGTP---- 291
                             G+PG  G  G  G +G +G+ GP    G+ G+PGP+G+P    
Sbjct: 677  DPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKG 736

Query: 292  -----GVAGPSGEPGMPGKDGQNGVP---GLDGQKGEAGRNGAPGEKGPNGLPGLPGRAG 343
                 G+ GP G+PG  G  G  G+P   GL G  GE G  G PG++G  G+PG PG  G
Sbjct: 737  YPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFG 796

Query: 344  SKGEKGERGRAGELGEAGPSGEPGV------------PGDAGMPGERGEAGHRGSAGALG 391
             +G  G  G  GELG  GP G PG+            PG  GM G  G  G  G  G  G
Sbjct: 797  ERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKG 856

Query: 392  PQGPPGAPGVRGFQGQKGSMGDPGLPGPQGL---RGDVGDRGPGGAAGPKGDQGIAGSDG 448
             QG PG  G  GFQG KGS G PG PG +G     G VGD+G  G  GP G +G  G  G
Sbjct: 857  EQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIG 916

Query: 449  LPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPG 508
             PGD G  G  G  G +G  G RG+LGP+G +GP G  G  G+ G PG  G  G PG+ G
Sbjct: 917  PPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDG 976

Query: 509  ITGKPGVPGK--EASEQRIRELCG-----GMISEQIAQ-------------LAAHLRKPL 548
            + G+PG PG+     EQ      G     G++ E+  +                H   P 
Sbjct: 977  VKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPG 1036

Query: 549  APGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGD------PGPRGNQGDRG 602
              G+ G PGP GPPG  GPPG  G  G RGP G  GP GE G       PGP+G  G  G
Sbjct: 1037 GMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG 1096

Query: 603  DKGAAG----------------------AGLDGPEGDQGPQGPQGVPG-TSKDGQDGAPG 639
             +G AG                       GL G  G QGPQGP G PG     G  GA G
Sbjct: 1097 QQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVG 1156

Query: 640  EPGPPGDPGLPGAIGAQGTPG 660
            EPG PG+ G+ G +G  GTPG
Sbjct: 1157 EPGLPGEAGMKGDLGPLGTPG 1177



 Score =  343 bits (879), Expect = 4e-94
 Identities = 201/473 (42%), Positives = 242/473 (51%), Gaps = 42/473 (8%)

Query: 16   LGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE 75
            LG L        +G  G PG  G  G  G DG+ G+ G PG  G  G KG  G  G+ G 
Sbjct: 1170 LGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGP 1229

Query: 76   AGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI 135
             G PG+ GV G  G+ G  G KG  G +G+ G  G   LG  G+PG PG  G  GP G  
Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQ--LGEMGVPGDPGPPGTPGPKGSR 1287

Query: 136  GLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPG----- 190
            G  GP G  G  G  G PG  G  GH G+            + P GPPGP G  G     
Sbjct: 1288 GSLGPTGAPGRMGAQGEPGLAGYDGHKGI------------VGPLGPPGPKGEKGEQGED 1335

Query: 191  --FKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGP 248
               +GP G  G++G VG  G++G+PG P   G PG  G+Q   GLRG PG  G PG  GP
Sbjct: 1336 GKAEGPPGPPGDRGPVGDRGDRGEPGDP---GYPGQEGVQ---GLRGKPGQQGQPGHPGP 1389

Query: 249  IGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT---PGVAGPSGEPGMPGK 305
             G+ GP G  GA G  G +G+ G  G RG +G  G PGP+G     G+ G +G  G+PG+
Sbjct: 1390 RGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGR 1449

Query: 306  DGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGEL-------- 357
            DGQ G  G  G  G+ G  G  G++G  G+ GLPG  G  G KGE G  G+L        
Sbjct: 1450 DGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGT 1509

Query: 358  -GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL 416
             G  G  G  G PG  G PG+ GE G  G AG  GP+GPPG  G +G QG +   G PGL
Sbjct: 1510 EGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPR---GPPGL 1566

Query: 417  PGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESG 469
             G +G+ G +G  GP G  GPKGD+G  G  GL G +G  GP G  GP G  G
Sbjct: 1567 MGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619



 Score =  164 bits (415), Expect = 3e-40
 Identities = 99/223 (44%), Positives = 113/223 (50%), Gaps = 35/223 (15%)

Query: 23   AGAQ-RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPG---------------PPGPKGA 66
            AGA  R G+ G  G PGP G  G+ G++G AGP GLPG                PGP G 
Sbjct: 1411 AGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGP 1470

Query: 67   PGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPG----LGGKGLPGP 122
             GK G PG AGLPG  G  G  G  G PG  G PG+RG+ G  G PG     G KG PG 
Sbjct: 1471 AGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGD 1530

Query: 123  PGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGP 182
             GE G  G  G  G +GPPG  G  G+ GP GPPG  G  G+            + P G 
Sbjct: 1531 SGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGI------------VGPLGI 1578

Query: 183  PGPPGMPGFKGPTGYKGE---QGEVGKDGEKGDPGPPGPAGLP 222
             GP G+PG KG  G +G+   QG  G  G +G PGPPGP G P
Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621



 Score =  139 bits (351), Expect = 7e-33
 Identities = 97/262 (37%), Positives = 119/262 (45%), Gaps = 55/262 (20%)

Query: 433 GAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP 492
           G  GPKGD G+ G  GLPG  G  G  G  GP G  G+ G  GP G +G  G  G+   P
Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLS--P 682

Query: 493 GPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGS 552
           G     G +G  G+PG++G PG PG++                               G 
Sbjct: 683 GKAHD-GAKGDMGLPGLSGNPGPPGRK-------------------------------GH 710

Query: 553 IGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA--- 609
            G PGPAG PG  G PG  G PGA+G PG +G  G +GDPGP+G++G  G  G  G    
Sbjct: 711 KGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGS 770

Query: 610 ----GLDGPEGDQGPQGPQGVPGT----------SKDGQDGAPGEPGPPGDPGLPGAIGA 655
               GL G  G +G  G  G PG              G+ G PG PG PG  G  G +G 
Sbjct: 771 DGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGP 830

Query: 656 QGTPGICDTSACQGAVLGGVGE 677
            G PG       +G ++G VGE
Sbjct: 831 IGYPG---PKGMKG-LMGSVGE 848



 Score =  104 bits (259), Expect = 3e-22
 Identities = 67/148 (45%), Positives = 74/148 (50%), Gaps = 4/148 (2%)

Query: 537 IAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRG 596
           I  LA     PL  G  G  G  G PGPPG PG  G PGARGP G  GP G  G PGP G
Sbjct: 611 IFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPG 670

Query: 597 NQGDRGDKGAA-GAGLDGPEGDQGPQGPQGVPGT-SKDGQDGAPGEPGPPGDPGLPGAIG 654
            +G +GD G + G   DG +GD G  G  G PG   + G  G PG  G PG+ G PG  G
Sbjct: 671 AKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEG 730

Query: 655 AQGTPGICDTSACQGAVLGGVGEKSGSR 682
           + G  G        G V G  G K GSR
Sbjct: 731 SPGAKGYPGRQGLPGPV-GDPGPK-GSR 756



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 66/226 (29%), Positives = 78/226 (34%), Gaps = 46/226 (20%)

Query: 464 PKGESGSRGELGPKGTQGP--NGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEAS 521
           P    GS     P  T  P  +GTS  +  P  P P            TG     G EAS
Sbjct: 491 PAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAP--------TGSKKPIGSEAS 542

Query: 522 EQRIRELCGGMISEQIAQLAAHLRKP--LAPGSIGRPGPAGP----PGPPGPPGSIGHPG 575
           ++              A   +  RKP  L PG   R  P       P P  P      P 
Sbjct: 543 KK--------------AGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQP-----QPS 583

Query: 576 ARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-------GLDGPEGDQGPQGPQGVPG 628
            +  P       +     PR           AG+       G  GP+GD G  GP G+PG
Sbjct: 584 QQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPG 643

Query: 629 T----SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGA 670
                   G  G PG  G PG PG PGA G +G PG+    A  GA
Sbjct: 644 LPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGA 689


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  505 bits (1301), Expect = e-143
 Identities = 306/709 (43%), Positives = 356/709 (50%), Gaps = 118/709 (16%)

Query: 28   VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPG---KPGKPGEAGLPGLPGV 84
            +GL G  GPPG PG PG+ G  G  GPPG     G +G PG   +PG PG AG PG PG 
Sbjct: 1262 MGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGA 1321

Query: 85   DGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK-------GLPGPPGEAGVSGPPG---- 133
             GL G  G PGP+G PGERG  GP G PG  G+       GLPG  G+ G SGPPG    
Sbjct: 1322 PGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGP 1381

Query: 134  ----------GI------------GLRGPPGPS------------GLPGLPGPPGPPGPP 159
                      G+            G RGPPGP             GLPG PGP GP GPP
Sbjct: 1382 LGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPP 1441

Query: 160  ---GHPGVLPEGATDL--QCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPG 214
               G  G   +GA  L  Q  S    GP GPPG  G KG  G+ G  GE G+ GE+G PG
Sbjct: 1442 GKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPG 1501

Query: 215  PPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEG 274
            P G  GLPG  G  G +G  G PGP G  G++G  G  G P + G P  AG +GE+G  G
Sbjct: 1502 PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG-PAVAGPKGEKGDVG 1560

Query: 275  FRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNG 334
              GP+G  G  G +G PG+  P G+PG  G  G  G  GL G+ G  G +G PGEKG  G
Sbjct: 1561 PAGPRGATGVQGERGPPGLVLP-GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPG 1619

Query: 335  LPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQG 394
             PG PG  G +G  GE    GE G+ GP G+PG+PG AG  G RG  G RG  G  G QG
Sbjct: 1620 RPGPPGPVGPRGRDGE---VGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG 1676

Query: 395  PPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPG----------GAAGPKGDQGIA 444
             PG  G  G  G  G  GD G PGP G  G + D GPG          G  GP+G +G  
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP 1736

Query: 445  GSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGP---NGTSGVQGVPGPPGPLGLQ 501
            G  G PG++G  G  G  GP+G+ G RG  G KG +GP   +G SG+ G PG  GP G  
Sbjct: 1737 GLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPN 1796

Query: 502  GVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP 561
            G  G  G  G+ G+PG                                 G  G PGP+GP
Sbjct: 1797 GAAGKAGDPGRDGLPGLR-------------------------------GEQGLPGPSGP 1825

Query: 562  PGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQ-- 618
            PG PG PG        G PG  G  GE GDPG  G +G++GD GA+G  G DGP+G++  
Sbjct: 1826 PGLPGKPGE------DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGA 1879

Query: 619  ----GPQGPQGVP---GTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
                GPQGP G+P   G    G  G PG  GP GD G  G+ G QG PG
Sbjct: 1880 PGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPG 1928



 Score =  503 bits (1295), Expect = e-142
 Identities = 325/768 (42%), Positives = 373/768 (48%), Gaps = 135/768 (17%)

Query: 14   LLLGELLAAAGAQRVGLPGPPGPPGPP---------GKPGQDGIDGEA---------GPP 55
            L LGE      +   G PG PG PG P         G+PG+ G  GE          GPP
Sbjct: 2019 LALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPP 2078

Query: 56   GLPGPPGPKGAPGK--------PGKPGEAGLPGLPGVDGLTGRDGPPGPK---------- 97
            GLPG PGP G PG         PG  GE G PGL G  G  G +G  GPK          
Sbjct: 2079 GLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG 2138

Query: 98   --------------GAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPG 142
                          G PGERG  GP G PGL G +G PGP G  G  GPPG  GL GP G
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 143  PSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGM------PGFKGPTG 196
            P G  GL G PG  GPPG     P GA  L       PGPPGP G+      PG  G  G
Sbjct: 2199 PQGPSGLKGEPGETGPPGRGLTGPTGAVGL-------PGPPGPSGLVGPQGSPGLPGQVG 2251

Query: 197  YKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPG 256
              G+ G  G+DG  G  G  G  G+PGS GL GP G +G PGP G PG +  +G  G  G
Sbjct: 2252 ETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPG-QAVVGLPGAKG 2310

Query: 257  IPGAP-GKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLD 315
              GAP G AGD       G  G KGD G PGP+G  G AG +GEPG PG+DGQ G PG  
Sbjct: 2311 EKGAPGGLAGDL-----VGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPK 2365

Query: 316  GQKGEAGRN--------GAPGEKGPNGLPGL---------PGRAGSKGEKGERGRAGELG 358
            G KG+ G          G PG KG  GLPGL         PG+ G +GE G+ G +GE G
Sbjct: 2366 GFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERG 2425

Query: 359  EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGA-----------PGVRGFQGQ 407
             AGP G  G+PG  G PG  G  G  G++G  G +G PG            PG+RG  G+
Sbjct: 2426 LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGR 2485

Query: 408  KGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIA-------GSDGLPGDKGELGPSG 460
             G  G  GL GP G RG+ G++G  G+AG KGD+G +       G  G  GD GE GP G
Sbjct: 2486 PGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRG 2545

Query: 461  LVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA 520
            L G KG  G  G+ G KG++G  G  G  G+PG  G LG QG PG  GI G PG PGK+ 
Sbjct: 2546 LDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKD- 2604

Query: 521  SEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGH------- 573
                IR   G +       L        A G  G  G  G  GPPG PG  GH       
Sbjct: 2605 GVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEP 2664

Query: 574  --PGARGPPGYRGPTGELGD------PGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQ 624
              PG  G PG  G  G  GD      PGP+G+QG++G++G  G  G  GP G+ G  GP 
Sbjct: 2665 GVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPP 2724

Query: 625  GVPGT----SKDGQDGAPGEPGPPGD--------PGLPGAIGAQGTPG 660
            G PG+      +G  G  GE GPPG+        PG PG  G QG PG
Sbjct: 2725 GPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPG 2772



 Score =  503 bits (1295), Expect = e-142
 Identities = 317/753 (42%), Positives = 373/753 (49%), Gaps = 116/753 (15%)

Query: 29   GLPGPPGPPGPPG------KPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLP 82
            GLPG PGPPGPPG      +PG  G+ GE GPPGL G  G  G+ G  G  G+ G+PG+ 
Sbjct: 2079 GLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIK 2137

Query: 83   GVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGG-KGLPGPPGEAGVSGPPGGIGLRGPP 141
            G  G  G  G  G  G PGERG  GP G PGL G +G PGP G  G  GPPG  GL GP 
Sbjct: 2138 GDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPA 2197

Query: 142  GPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQ 201
            GP G  GL G PG  GPPG     P GA  L          PGPPG  G  GP G  G  
Sbjct: 2198 GPQGPSGLKGEPGETGPPGRGLTGPTGAVGL----------PGPPGPSGLVGPQGSPGLP 2247

Query: 202  GEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPP--GIPG 259
            G+VG+ G+ G PG  G +G  G  G  G  G  GLPGP+GP G+ GP G  G    G+PG
Sbjct: 2248 GQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPG 2307

Query: 260  APGKAGDRGERGPE--GFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQ 317
            A G+ G  G    +  G  G KGD G PGP+G  G AG +GEPG PG+DGQ G PG  G 
Sbjct: 2308 AKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGF 2367

Query: 318  KGEAGRN--------GAPGEKGPNGLPGLPG---------RAGSKGEKGERGRAGELGEA 360
            KG+ G          G PG KG  GLPGLPG         + G +GE G+ G +GE G A
Sbjct: 2368 KGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLA 2427

Query: 361  GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGA-----------PGVRGFQGQKG 409
            GP G  G+PG  G PG  G  G  G++G  G +G PG            PG+RG  G+ G
Sbjct: 2428 GPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPG 2487

Query: 410  SMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIA-------GSDGLPGDKGELGPSGLV 462
              G  GL GP G RG+ G++G  G+AG KGD+G +       G  G  GD GE GP GL 
Sbjct: 2488 QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLD 2547

Query: 463  GPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASE 522
            G KG  G  G+ G KG++G  G  G  G+PG  G LG QG PG  GI G PG PGK+   
Sbjct: 2548 GDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVP 2607

Query: 523  QRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGH--------- 573
              IR   G +       L        A G  G  G  G  GPPG PG  GH         
Sbjct: 2608 G-IRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGV 2666

Query: 574  PGARGPPGYRGPTGELGD------PGPRGNQGDRGDKGAAG-------------AGLDGP 614
            PG  G PG  G  G  GD      PGP+G+QG++G++G  G             AG  GP
Sbjct: 2667 PGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGP 2726

Query: 615  EGDQGPQGPQGVPGTSKD------------GQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662
             G  GP+GP+G+ G   +            G  GAPGE G  G PG  G  G +G   + 
Sbjct: 2727 PGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALT 2786

Query: 663  DTS-------------ACQGAVLGGVGEKSGSR 682
            +               ACQG  +      SGSR
Sbjct: 2787 EDDIRGFVRQEMSQHCACQGQFIA-----SGSR 2814



 Score =  495 bits (1275), Expect = e-140
 Identities = 323/823 (39%), Positives = 383/823 (46%), Gaps = 181/823 (21%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGL--PGLPGVDG 86
            G  GPPGP G  G PG  G  G  GP G PGP G +G  G+PG+PG+  +  P + G  G
Sbjct: 1495 GERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKG 1554

Query: 87   LTGRDGPPGPKGAPGERGSLGPPG---PPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGP 143
              G  GP GP+GA G +G  GPPG   P   G KG PG  G  G++G  G  G  GPPG 
Sbjct: 1555 EKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGE 1614

Query: 144  SGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGM---------PGFKGP 194
             G PG PGPPGP GP G  G + E   +       PPG PG PG          PG +GP
Sbjct: 1615 KGDPGRPGPPGPVGPRGRDGEVGEKGDE------GPPGDPGLPGKAGERGLRGAPGVRGP 1668

Query: 195  TGYKGEQGEVGKDG------------EKGDPGPPGPAGL-------------PGSVGLQG 229
             G KG+QG+ G+DG            ++G+PGPPGP G              PG  G +G
Sbjct: 1669 VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEG 1728

Query: 230  PRGLRGLPGPLGPPGDRGPIGFRGPPGI---PGAPGKAGDRGERGPEGF----------- 275
            PRG +G PG  G PG+RG  GFRGPPG    PG  G AG++G+RGP G            
Sbjct: 1729 PRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPG 1788

Query: 276  ----------RGPKGDLGR---PGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAG 322
                       G  GD GR   PG +G  G+ GPSG PG+PGK G++G PGL+G+ GE G
Sbjct: 1789 AAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPG 1848

Query: 323  RNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGP-----------SGEPGVPGD 371
              G  G KG  G  G  GR G  G KGERG  G LG  GP            G PGVPG 
Sbjct: 1849 DPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG 1908

Query: 372  AGMPGERGEAGHRGSAGALGPQGPPGAPGV------------------------------ 401
             G  G+RGE G +G  G  G +G  G PG                               
Sbjct: 1909 TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSG 1968

Query: 402  ---------RGFQGQKGSMGDP------GLPGPQGLRGD-------------VGDRGPGG 433
                     RG +G  G  G P      G PG +GL+GD             +G+RGP G
Sbjct: 1969 SFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPG 2028

Query: 434  AAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPG 493
             +G  G+ G  G  GLPG  G +G +G  G +GE G +GE G +G  GP G  G  G PG
Sbjct: 2029 PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPG 2088

Query: 494  PPGPL--------GLQGVPGVPGITGKPGVPGKEASE--QRIRELCGGMISEQIAQLAAH 543
            PPGP         GL G  G PG+ G  G PG    +  +  R + G             
Sbjct: 2089 PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148

Query: 544  LRKPLAPGSIGRPGPAGPP---GPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD 600
               P  PG  G  GP G P   GP GPPG +G  G  GPPG  G  G  G  GP G +G+
Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGE 2208

Query: 601  RGDKGAAGAGLDGPEGD------------QGPQGPQGVPG----TSK---------DGQD 635
             G+ G  G GL GP G              GPQG  G+PG    T K          G+D
Sbjct: 2209 PGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKD 2268

Query: 636  GAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678
            G  G PG PG PGLPG +G +G PG   T A   AV+G  G K
Sbjct: 2269 GDRGSPGVPGSPGLPGPVGPKGEPG--PTGAPGQAVVGLPGAK 2309



 Score =  492 bits (1267), Expect = e-139
 Identities = 322/776 (41%), Positives = 364/776 (46%), Gaps = 156/776 (20%)

Query: 24   GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGP------KGAPGKPGKPGEAG 77
            G    G PG PG PG PG+ G  G  G  GP G  G PGP      KG  G PG  G  G
Sbjct: 1448 GDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRG 1507

Query: 78   LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGL 137
            LPG+ G  G  G +GPPGP G  GE+G  G PG P + G  + GP GE G  GP G  G 
Sbjct: 1508 LPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGA 1567

Query: 138  RGPPGPSGLPG--LPGPPGPPGPPGHPGVLPEGATDLQCP--SICPPGPPGPPGMPGFKG 193
             G  G  G PG  LPG PGP G PG  G  P G T    P     PPG  G PG PG  G
Sbjct: 1568 TGVQGERGPPGLVLPGDPGPKGDPGDRG--PIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625

Query: 194  PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL------------- 240
            P G +G  GEV   GEKGD GPPG  GLPG  G +G RG  G+ GP+             
Sbjct: 1626 PVGPRGRDGEV---GEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDG 1682

Query: 241  --GPPGDRGPIGFRGPPGIPGAPGK----------AGDRGERGPEGFRGPKGD------- 281
              G PG  GP G RG PG PG PG+           G+ G+RG EG RGPKGD       
Sbjct: 1683 RNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAP 1742

Query: 282  --------LGRPGPKGTPGVAGPSGEP---GMPGKDGQNGV------------------- 311
                     G PGP+G PGV GP+GE    G PG DG++G+                   
Sbjct: 1743 GERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKA 1802

Query: 312  --PGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVP 369
              PG DG  G  G  G PG  GP GLPG PG  G  G  G+ G  G+ GE G  GE G  
Sbjct: 1803 GDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDS 1862

Query: 370  GDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDR 429
            G +G  G  G  G RG+ G LGPQGPPG PG  G  GQ G  G PG  GP+G RG+ G +
Sbjct: 1863 GASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQ-GFPGVPGGTGPKGDRGETGSK 1921

Query: 430  GPGGAAGPKGDQGIAGS---------------------------------------DGLP 450
            G  G  G +G +G  GS                                        G  
Sbjct: 1922 GEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPK 1981

Query: 451  GDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQ-GVPGPPGPLGLQGVPGVPGI 509
            GD GE GP G  GP G  G RG  G +G  GP G  G+  G  GPPGP GL G PG PGI
Sbjct: 1982 GDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGI 2041

Query: 510  TGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPG 569
             G PG  G      R  E   G   E+         +    G  G PG  GPPGPPGP  
Sbjct: 2042 PGLPGRAGGVGEAGRPGE--RGERGEK-----GERGEQGRDGPPGLPGTPGPPGPPGPKV 2094

Query: 570  SIGHP-----GARGPPGYRGPTGE---LGDPGPRGN------QGDRGDKGAAG------- 608
            S+  P     G +GPPG +G  GE    GD GP+G+      +GDRG+ G  G       
Sbjct: 2095 SVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGL 2154

Query: 609  ---AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
                G+ GPEG  G QGP+G PG       G  G+PGPPG PGL G  G QG  G+
Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPV-----GGHGDPGPPGAPGLAGPAGPQGPSGL 2205



 Score =  485 bits (1248), Expect = e-137
 Identities = 310/732 (42%), Positives = 357/732 (48%), Gaps = 137/732 (18%)

Query: 29   GLPGPPGPPG----PPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGV 84
            G PGP GPPG      G PG  G+ GE G PG+PG PG  G  G+ G+PGE G  G  G 
Sbjct: 2009 GDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGE 2068

Query: 85   DGLTGRDGPPGPKGAPGERGSLGPPGP------PGLGGKGLPGPPGEAGVSGPPGGIGLR 138
             G  GRDGPPG  G PG  G   PPGP      PG G  G  GPPG  G  G PG  G +
Sbjct: 2069 RGEQGRDGPPGLPGTPGPPG---PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQ 2125

Query: 139  GPPGPSGLPGLPGPPGPPGP------PGHPGVL----PEGATDLQCPSICPPGP------ 182
            GP G  G+PG+ G  G PGP      PG PG      PEG   LQ P   PPGP      
Sbjct: 2126 GPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPR-GPPGPVGGHGD 2184

Query: 183  PGPPGMPGF------KGPTGYKGEQGEV--------GKDGEKGDPGPPGPAGL------- 221
            PGPPG PG       +GP+G KGE GE         G  G  G PGPPGP+GL       
Sbjct: 2185 PGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSP 2244

Query: 222  --------------PGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA--- 264
                          PG  G  G  G RG PG  G PG  GP+G +G PG  GAPG+A   
Sbjct: 2245 GLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVG 2304

Query: 265  --GDRGERGPEGFR--------GPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGL 314
              G +GE+G  G          G KGD G PGP+G  G AG +GEPG PG+DGQ G PG 
Sbjct: 2305 LPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGP 2364

Query: 315  DGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGM 374
             G KG+ G  G PG  GP G PG+ G  G  G  G  G  G  G+ GP GE G PG +G 
Sbjct: 2365 KGFKGDPGV-GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGE 2423

Query: 375  PGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPG--LPGPQGLRGDVGDRGPG 432
             G  G  G  G  G LGP GPPG+ G  G  G KG  GDPG  LPGP+G RG+ G RG  
Sbjct: 2424 RGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGED 2483

Query: 433  GAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR----GELGPKGTQGPNGTSGV 488
            G  G +G +G+ G  G  G++GE G  G  G KG+ G      G  GP+G +G  G  G 
Sbjct: 2484 GRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGP 2543

Query: 489  QGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPL 548
            +G+ G  GP G  G PG  G  G+PG  G                               
Sbjct: 2544 RGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAG---------------------------- 2575

Query: 549  APGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG 608
             PG  G  GP G PG  G PG  G PG  G PG RG  G++G  GPRG +G+RG KGA G
Sbjct: 2576 LPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACG 2635

Query: 609  AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQ 668
              LDG +GD+G                    E GPPG PGL G  G  G PG+   S   
Sbjct: 2636 --LDGEKGDKG--------------------EAGPPGRPGLAGHKGEMGEPGVPGQSGAP 2673

Query: 669  G--AVLGGVGEK 678
            G   ++G  G++
Sbjct: 2674 GKEGLIGPKGDR 2685



 Score =  482 bits (1240), Expect = e-136
 Identities = 324/770 (42%), Positives = 364/770 (47%), Gaps = 135/770 (17%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP-----GPPGPKGAPGKPG 71
            G+++   G    G  G PGP GPPG  G  G  G  GPPGLP     G  G +G  G PG
Sbjct: 1353 GQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPG 1412

Query: 72   KPGEAGL-PGLPGVDGLTGRDGPPGPKGAPGERGSLG--PPGPPGLGGKGLPGPPGEAGV 128
             PGE G+ PG PG+ GL G  GP GP G PG++G  G    G PGL G+  PG PGE G 
Sbjct: 1413 -PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQ--PGSPGEQGP 1469

Query: 129  SGPPGGIGLR------GPPGPSGLPGLPGPPGPPGPPGHPGVLPE-GATDLQCPSICPPG 181
             GPPG IG +      GP G +G  G  GPPGP G  G PGV    GA         P G
Sbjct: 1470 RGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKG-------PEG 1522

Query: 182  PPGPPGMPGFKGPTGYKGEQGEV-----GKDGEKGDPGPPGPAGLPGSVGLQGPRG--LR 234
            PPGP G  G KG  G  G+   V     G  GEKGD GP GP G  G  G +GP G  L 
Sbjct: 1523 PPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLP 1582

Query: 235  GLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVA 294
            G PGP G PGDRGPIG  G  G PG  G  G++G+ G  G  GP G  GR G  G  G  
Sbjct: 1583 GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDE 1642

Query: 295  GPSGEPGMPGKDGQNGV---PGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGER 351
            GP G+PG+PGK G+ G+   PG+ G  GE G  G PGE G NG PG  G  G +GE G  
Sbjct: 1643 GPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPP 1702

Query: 352  GRAGELGEAGPSG-EPGVPGDAGMPGER---------GEAGHRGSAGALGPQGPPGAPGV 401
            G  G L + GP   E G PGD G  G R         G  G RG  G  GP GP G PGV
Sbjct: 1703 GPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGV 1762

Query: 402  RGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE------ 455
            RG  G+KG  G PGL G  GL G  G  GP G  G  G  G  G DGLPG +GE      
Sbjct: 1763 RGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGP 1822

Query: 456  LGPSGLVGPKGE------------------------------SGSRGELGPKGTQGPNGT 485
             GP GL G  GE                              SG  G  GPKG +G  G 
Sbjct: 1823 SGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGI 1882

Query: 486  SGVQGVPGPPGPLGL--QGVPGVPGITGKP---------------------GVPGKEASE 522
             G QG PG PGP+G   QG PGVPG TG                       G PG   + 
Sbjct: 1883 LGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNV 1942

Query: 523  QRIRELCGGMIS--EQIAQ---------LAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSI 571
             R+ E  G   S   +I +         L    R+    G  G  GP G  GP G PG  
Sbjct: 1943 DRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGER 2002

Query: 572  GHPGARGPPGYRGP----TGELGDPGPRGNQGDRGDKG-------AAGAGLDGPEGDQGP 620
            G  G RG PG +GP     GE G PGP G  G+ G  G       A G G  G  G++G 
Sbjct: 2003 GLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGE 2062

Query: 621  QGPQGVPG-TSKDGQDGAPGEPGPPGDPGL--------PGAIGAQGTPGI 661
            +G +G  G   +DG  G PG PGPPG PG         PG  G QG PG+
Sbjct: 2063 RGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL 2112



 Score =  472 bits (1215), Expect = e-133
 Identities = 323/820 (39%), Positives = 380/820 (46%), Gaps = 190/820 (23%)

Query: 29   GLPGPPGPPGPPGK---PGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGL------P 79
            G  GP GP G  GK   PG+DG+ G  G  GLPGP GP G PGKPG+ G+ GL      P
Sbjct: 1788 GAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEP 1847

Query: 80   GLPGVDG---------LTGRDGPPGPKGAPGERGSLGPPGPPGL------GGKGLPGPPG 124
            G PG DG          +GR+G  GPKG  G  G LGP GPPGL       G+G PG PG
Sbjct: 1848 GDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPG 1907

Query: 125  EAGVSGP------------PGGIGLRGPP------------------------------- 141
              G  G             PG  GLRG P                               
Sbjct: 1908 GTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESS 1967

Query: 142  -----------GPSGLPGLPGPPGPPGPPGHPGVL----------PEGATDLQCPSICPP 180
                       GP G  G  GPPG  GP G PG            P+G   L      PP
Sbjct: 1968 GSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027

Query: 181  GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240
            GP G  G PG  G  G  G  G VG+ G  G+ G  G  G  G  G  GP GL G PGP 
Sbjct: 2028 GPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPP 2087

Query: 241  GPPGDR--------GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGP---KGDLGRPGPKG 289
            GPPG +        G  G +GPPG+ GA G+ G  G++GP+G RG    KGD G PGP+G
Sbjct: 2088 GPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG 2147

Query: 290  TPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKG 349
              G  G  GE GM G +G+   PGL G +G  G  G  G+ GP G PGL G AG +G  G
Sbjct: 2148 QDGNPGLPGERGMAGPEGK---PGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSG 2204

Query: 350  ERGRAGELGE-----AGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGF 404
             +G  GE G       GP+G  G+PG  G  G  G  G  G  G +G  G PGAPG  G 
Sbjct: 2205 LKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGA 2264

Query: 405  QGQKGSMGDPGLPGPQGLRGDVGDRG------------------------PGGAAGP-KG 439
             G+ G  G PG+PG  GL G VG +G                        PGG AG   G
Sbjct: 2265 SGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVG 2324

Query: 440  DQGIAGSDGLP---GDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPG 496
            + G  G  GLP   G+KGE G +G  G  GE G +G  GPKG +G  G  GV G PGPPG
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GVPGSPGPPG 2383

Query: 497  P------LGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLA- 549
            P      LGL G+PG PG+ G PG  G                  ++ Q      + LA 
Sbjct: 2384 PPGVKGDLGLPGLPGAPGVVGFPGQTGPRG---------------EMGQPGPSGERGLAG 2428

Query: 550  -PGSIGRPGPAGPPGPP---GPPGSIGHPGARGPP--GYRGPTGELGDP----------- 592
             PG  G PGP GPPGPP   GPPG+ G  G +G P  G  GP GE G+P           
Sbjct: 2429 PPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQ 2488

Query: 593  -------GPRGNQGDRGDKGAAG-AGLDGPEGDQ----GPQGPQGVPG-TSKDGQDGAPG 639
                   GP G++G+RG+KG  G AGL G +GD     GP GP+G  G   + G  G  G
Sbjct: 2489 EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDG 2548

Query: 640  EPGPPGDPGLPGAIGAQGTPGICDTSACQG--AVLGGVGE 677
            + GP GD G PG  G++G PG   ++   G   +LG  G+
Sbjct: 2549 DKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQ 2588



 Score =  431 bits (1107), Expect = e-120
 Identities = 283/686 (41%), Positives = 328/686 (47%), Gaps = 125/686 (18%)

Query: 93   PPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI---GLRGPPGPSGLPGL 149
            P G KG PGE G  G  GPPG    GLPG  G  G  GPPG     G RG PG  G PG 
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPG--DPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGS 1309

Query: 150  PGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGK--- 206
            PG  G PG PG PG+  +G+          PG PGP G PG +GP G KGE G  G+   
Sbjct: 1310 PGRAGNPGTPGAPGL--KGS----------PGLPGPRGDPGERGPRGPKGEPGAPGQVIG 1357

Query: 207  ------DGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL--GPPGDRGPIGFRGP---- 254
                   G KGDPGP GP G  G +G  GPRG  GLPG    G  GDRG  G  GP    
Sbjct: 1358 GEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGG 1417

Query: 255  -----PGIPGAPGKAGDRGERGPEGFRGPKGDL-----GRPGPKGTPGVAGPSGEPGMPG 304
                 PG+PG PG  G +G  GP G +G KGD      G PG  G+PG  GP G PG  G
Sbjct: 1418 IAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIG 1477

Query: 305  KDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSG 364
              G  G PG  G+ GE G  G PG  G  GLPG+ GR G+KG +G  G  G  GE    G
Sbjct: 1478 PKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGE---KG 1534

Query: 365  EPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG 424
            EPG PGD  + G    AG +G  G +GP GP GA GV+G +G  G +    LPG  G +G
Sbjct: 1535 EPGRPGDPAVVGP-AVAGPKGEKGDVGPAGPRGATGVQGERGPPGLV----LPGDPGPKG 1589

Query: 425  DVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNG 484
            D GDRGP G  G  G  G +G  G  GD G  GP G VGP+G  G  GE G +G  G  G
Sbjct: 1590 DPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPG 1649

Query: 485  TSG------VQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538
              G      ++G PG  GP+G +G  G PG  G+ G PG    +    E        ++ 
Sbjct: 1650 LPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLV 1709

Query: 539  QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQ 598
                  R+   PG  G+ GP GP G PG PG+   PG RG  G+RGP G  GDPG RG  
Sbjct: 1710 DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGA---PGERGIEGFRGPPGPQGDPGVRGPA 1766

Query: 599  GDRGDKGAAG----AGLDGPEGDQGPQGP---------------------QGVPGTS--- 630
            G++GD+G  G    +GLDG  G  GP GP                     QG+PG S   
Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP 1826

Query: 631  ----KDGQDGAPG------EPGPPGDPG------------------------LPGAIGAQ 656
                K G+DG PG      EPG PG+ G                         PG +G Q
Sbjct: 1827 GLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQ 1886

Query: 657  GTPGICDTSACQG----AVLGGVGEK 678
            G PG+       G     V GG G K
Sbjct: 1887 GPPGLPGPVGPPGQGFPGVPGGTGPK 1912



 Score =  407 bits (1045), Expect = e-113
 Identities = 266/622 (42%), Positives = 310/622 (49%), Gaps = 74/622 (11%)

Query: 127  GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL-PEGATDLQCPSICP-----P 180
            G  G PG +GLRG  GP      PG PG PG  G PG   P G+   +     P     P
Sbjct: 1254 GQKGEPGEMGLRGQVGP------PGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRP 1307

Query: 181  GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGS----VGLQGP--RGLR 234
            G PG  G PG  G  G KG  G  G  G+ G+ GP GP G PG+    +G +GP   G +
Sbjct: 1308 GSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRK 1367

Query: 235  GLPGPLGPPGDRGPIGFRGPPGIPGAPGKA-----GDRGERGP----EGFRGPKGDLGRP 285
            G PGP GPPG RGP+G  GP G PG PG A     GDRGERGP    EG   P G+ G P
Sbjct: 1368 GDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAP-GEPGLP 1426

Query: 286  GPKGTPGVAGPSGEPGMPG-----KDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPG 340
            G  G+PG  GP G PG  G     +DG  G+PG  G  GE G  G PG  GP G  G PG
Sbjct: 1427 GLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPG 1486

Query: 341  RAGSKGEKGER---GRAGELGEAGPSGEPGV------PGDAGMPGERGEAGHRGSAGALG 391
              G  GEKGER   G AG  G  G +G PG       PG  G  GE+GE G  G    +G
Sbjct: 1487 PLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG 1546

Query: 392  P--------QGPPGAPGVRGFQGQKGSMGDPG--LPGPQGLRGDVGDRGPGGAAGPKGDQ 441
            P        +G  G  G RG  G +G  G PG  LPG  G +GD GDRGP G  G  G  
Sbjct: 1547 PAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPP 1606

Query: 442  GIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPK------GTQGPNGTSGVQGVPGPP 495
            G +G  G  GD G  GP G VGP+G  G  GE G +      G  G  G  G++G PG  
Sbjct: 1607 GDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVR 1666

Query: 496  GPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGR 555
            GP+G +G  G PG  G+ G PG    +    E        ++       R+   PG  G+
Sbjct: 1667 GPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQ 1726

Query: 556  PGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG----AGL 611
             GP GP G PG PG+   PG RG  G+RGP G  GDPG RG  G++GD+G  G    +GL
Sbjct: 1727 EGPRGPKGDPGLPGA---PGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGL 1783

Query: 612  DGPEGDQGPQGPQGVPGTSKD-GQDGAP------GEPGPPGDPGLPGAIGAQGTPGICDT 664
            DG  G  GP GP G  G + D G+DG P      G PGP G PGLPG  G  G PG+   
Sbjct: 1784 DGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK 1843

Query: 665  SACQG--AVLGGVGEKSGSRSS 684
            +   G     G  GEK  S +S
Sbjct: 1844 NGEPGDPGEDGRKGEKGDSGAS 1865



 Score =  399 bits (1025), Expect = e-111
 Identities = 243/559 (43%), Positives = 282/559 (50%), Gaps = 87/559 (15%)

Query: 28   VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGL 87
            VGLPGPPGP G  G  G  G+ G+ G  G PG PG  GA GK G  G  G+PG PG+ G 
Sbjct: 2226 VGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGP 2285

Query: 88   TGRDGPPGPKGAPGE--------RGSLGPPG---------PPGLGGKGLPGPPGE----- 125
             G  G PGP GAPG+        +G  G PG         P   G +GLPGP GE     
Sbjct: 2286 VGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG 2345

Query: 126  -AGVSGPPGGIGLRGPPGPSG--------LPGLPGPPGPPGP---------PGHPGVL-- 165
             AG  G PG  G +G PGP G        +PG PGPPGPPG          PG PGV+  
Sbjct: 2346 RAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGF 2405

Query: 166  --------------PEGATDLQCPS-----ICPPGPPGPPGMPGFKGPTGYKGEQGE--V 204
                          P G   L  P        P GPPGPPG  G  G +G KG++G+  V
Sbjct: 2406 PGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV 2465

Query: 205  GKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIG-------------F 251
            G  G +G+ G PG  G  G  G +GPRGL G PG  G  G++G +G              
Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVI 2525

Query: 252  RGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV 311
             GPPG  GA G  G+RG RG +G +GP+GD G PG KG+ G  G  G  G+P   G  G+
Sbjct: 2526 LGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLP---GLRGL 2582

Query: 312  PGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGE---LGEAGPSGEPGV 368
             G  GQ G AG  G PG  G +G+PG+ G  G  G  G RG  GE    G  G  GE G 
Sbjct: 2583 LGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGD 2642

Query: 369  PGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGD 428
             G+AG PG  G AGH+G  G  G  G  GAPG  G  G KG  G  G PGP+G +G+ G+
Sbjct: 2643 KGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGE 2702

Query: 429  RGP---GGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGE--LGPKGTQGPN 483
            RG    GG  GP G+ G AG  G PG  G  GP GL G KGE G  GE  +G  G  G  
Sbjct: 2703 RGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAP 2762

Query: 484  GTSGVQGVPGPPGPLGLQG 502
            G  G QG PGP GP G +G
Sbjct: 2763 GERGEQGRPGPAGPRGEKG 2781



 Score =  339 bits (869), Expect = 6e-93
 Identities = 194/417 (46%), Positives = 223/417 (53%), Gaps = 18/417 (4%)

Query: 24   GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGL---PGPPGPKGAPGKPGKPGEAGLPG 80
            G   VG+PG PGPPGPPG  G  G+ G  G PG+   PG  GP+G  G+PG  GE GL G
Sbjct: 2369 GDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAG 2428

Query: 81   LPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGP 140
             PG +G+ G  GPPGP G+ G  G+ G  G  G  G GLPGP GE G  G  G  G  G 
Sbjct: 2429 PPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQ 2488

Query: 141  PGPSGLPGLPGPPGPPGPPGHPGVLP-EGATDLQCPSICPPGPPGPPGMPGFKGPTGY-- 197
             GP GL G PG  G  G  G  G    +G        + PPGP G  G  G +GP G   
Sbjct: 2489 EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDG 2548

Query: 198  ----KGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRG 253
                +G+ G+ G  G KG+PG  G AGLPG  GL GP   +G PG  G PGD G  G  G
Sbjct: 2549 DKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGP---QGQPGAAGIPGDPGSPGKDG 2605

Query: 254  PPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPG 313
             PGI G  G  G  G RG +G RG KG  G  G KG  G AGP G PG+ G  G+ G PG
Sbjct: 2606 VPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPG 2665

Query: 314  LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373
            + GQ G  G+ G  G KG  G  G PG  G +GEKGERG  G  G  GPSG  G  G  G
Sbjct: 2666 VPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPG 2725

Query: 374  MPGERGEAGHRGSAGALGPQGPP-----GAPGVRGFQGQKGSMGDPGLPGPQGLRGD 425
             PG  G  G  G  G  G +GPP     GAPGV G  G++G  G PG  GP+G +G+
Sbjct: 2726 PPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGE 2782



 Score =  328 bits (841), Expect = 1e-89
 Identities = 219/543 (40%), Positives = 257/543 (47%), Gaps = 97/543 (17%)

Query: 216  PGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGF 275
            P P  +    G +G  G  GL G +GPPGD G  G  G PG  G PG A  +GERG  G 
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGA 1303

Query: 276  RGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGV---------------------PGL 314
             G  G  GR G  GTPG  G  G PG+PG  G  G                      PGL
Sbjct: 1304 DGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGL 1363

Query: 315  DGQKGEAGRNGAP------GEKGPNGLPGLPGRA--GSKGEKGERGRAGELGEAG-PSGE 365
             G+KG+ G +G P      G+ GP G PGLPG A  G KG++GERG  G  GE G   GE
Sbjct: 1364 PGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGP-GEGGIAPGE 1422

Query: 366  PGVPGDAGMPGERGEAGHRGSA--------GALGPQGPPGAPGVRGFQGQKGSM---GDP 414
            PG+PG  G PG +G  G  G          GA G  G PG+PG +G +G  G++   GD 
Sbjct: 1423 PGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDR 1482

Query: 415  GLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGE------- 467
            G PGP G  G+ G+RGP G AG +G  G+AG  G  G +G  GP+G  G KGE       
Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542

Query: 468  -------SGSRGELGPKGTQGPNGTSGVQG--------VPGPPGPLGLQGVPGVPGITGK 512
                   +G +GE G  G  GP G +GVQG        +PG PGP G  G  G  G+TG+
Sbjct: 1543 AVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGR 1602

Query: 513  PGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAP----GSIGRPGPAGPPGPPGPP 568
             G PG             G   E+          P+ P    G +G  G  GPPG PG P
Sbjct: 1603 AGPPGD-----------SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLP 1651

Query: 569  GSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPG 628
            G  G  G RG PG RGP GE GD G  G  G  G  G++     GP+GD+G  GP G PG
Sbjct: 1652 GKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSS-----GPKGDRGEPGPPGPPG 1706

Query: 629  TSKD-----------GQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG--AVLGGV 675
               D           G  G  G  GP GDPGLPGA G +G  G       QG   V G  
Sbjct: 1707 RLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766

Query: 676  GEK 678
            GEK
Sbjct: 1767 GEK 1769



 Score =  149 bits (375), Expect = 1e-35
 Identities = 95/220 (43%), Positives = 108/220 (49%), Gaps = 28/220 (12%)

Query: 15   LLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGA---PGKPG 71
            LLG       A   G PG PG  G PG  G+ G  G  GP GL G  G KGA    G+ G
Sbjct: 2582 LLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKG 2641

Query: 72   KPGEAGLPGLPGV---DGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGV 128
              GEAG PG PG+    G  G  G PG  GAPG+ G +GP G  G  G+  PGP G+ G 
Sbjct: 2642 DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQ--PGPKGDQGE 2699

Query: 129  SGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGM 188
             G  G  G+ G PGPSG  G  GPPGPPG                  S+ P GP G  G 
Sbjct: 2700 KGERGTPGIGGFPGPSGNDGSAGPPGPPG------------------SVGPRGPEGLQGQ 2741

Query: 189  PGFKGPTGYK--GEQGEVGKDGEKGDPGPPGPAGLPGSVG 226
             G +GP G +  G  G  G  GE+G+ G PGPAG  G  G
Sbjct: 2742 KGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781



 Score =  112 bits (280), Expect = 1e-24
 Identities = 58/125 (46%), Positives = 68/125 (54%), Gaps = 6/125 (4%)

Query: 28   VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGL 87
            +G PG PG  G PGK G  G  G+ G  G PGP G +G  G+ G PG  G PG  G DG 
Sbjct: 2661 MGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGS 2720

Query: 88   TGRDGPPG------PKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPP 141
             G  GPPG      P+G  G++G  GPPG   +G  G+PG PGE G  G PG  G RG  
Sbjct: 2721 AGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEK 2780

Query: 142  GPSGL 146
            G + L
Sbjct: 2781 GEAAL 2785



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 29/79 (36%), Positives = 33/79 (41%), Gaps = 21/79 (26%)

Query: 612  DGPEGDQGPQG---------------PQGVPGTSKDGQDGAPGE------PGPPGDPGLP 650
            DGP  DQ   G               P+  P     GQ G PGE       GPPGDPGLP
Sbjct: 1218 DGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLP 1277

Query: 651  GAIGAQGTPGICDTSACQG 669
            G  GA G  G   ++  +G
Sbjct: 1278 GRTGAPGPQGPPGSATAKG 1296


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  504 bits (1298), Expect = e-142
 Identities = 305/702 (43%), Positives = 362/702 (51%), Gaps = 77/702 (10%)

Query: 29   GLPGPPGPPGPPGKPGQDG----------IDGEAGPPGLPGPPGPKGAPGKPGKPGEAGL 78
            G+PGP G PG  G+PG  G          + G+ G PG PG PG  G  G PG+ G  GL
Sbjct: 510  GVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGL 569

Query: 79   PG---LPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL---------GGKGLPGPPGEA 126
            PG    PG  GL G  GPPG  G PG RG  GPPGPPG          G  G PG PG  
Sbjct: 570  PGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSP 629

Query: 127  GVSGPPGGIG----LRGPPGPSGLPGLPGPPGP------PGPPGHPGVLPEGATDLQCPS 176
            G+ GP G  G    L GPPG  GLPG PG PGP      PG PG PG LP     +  P 
Sbjct: 630  GLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPG-LPGEKGAVGQPG 688

Query: 177  ICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGL 236
            I  PGPPGP G+ G  G  G  G  G  G +G  G+PG  G  G PG VGL G +GL GL
Sbjct: 689  IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG-VGLPGLKGLPGL 747

Query: 237  PGPLGPPGDRGPIGFRGPPGIPGA---PGKAGDRGERGPEGFRGPKGD-----LGRPGPK 288
            PG  G PG++G IG  G PG  GA   PG  G RGE GP G  G  G      +G PG +
Sbjct: 748  PGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGAR 807

Query: 289  GTPGVAGP---SGEPGMPGKDGQNGVPGLD--GQKGEAGRNGAPGEKGPNGLPGLPGRAG 343
            G PG  GP   SG PG+ G+ G  G PGLD  G KG+ G  G PG  G +GLPGLPG+ G
Sbjct: 808  GPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQG 867

Query: 344  SKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVR- 402
            + G  G  G  GE+G  G  G+PG PG  G PG  GE G  G  G+ GP+G PG  G + 
Sbjct: 868  APGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKG 927

Query: 403  --GFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG 460
              G  G+ GSM    +   +G +GD G++G  G  G KG +G  G+ G+PG  G+ G  G
Sbjct: 928  DVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPG 987

Query: 461  LVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA 520
              GPKG+ G  G  G  G  GP G+ G  G+PG PG    +GVPG+PG  G PG+PG + 
Sbjct: 988  QPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGE---KGVPGIPGPQGSPGLPGDKG 1044

Query: 521  SEQR----------IRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGS 570
            ++            I  L G    + IA       +    GSIG PG  G PG  G PGS
Sbjct: 1045 AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS 1104

Query: 571  IGHPGARGPPGYRGP------------TGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQ 618
            +G+PG+ G PG +G              GE G PG  G  G  G KG  G+  DG  G  
Sbjct: 1105 VGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGS--DGIPGSA 1162

Query: 619  GPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
            G +G  G+PG    G  GA G+ G  G+ G PG  G+ G PG
Sbjct: 1163 GEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPG 1204



 Score =  502 bits (1293), Expect = e-142
 Identities = 316/730 (43%), Positives = 358/730 (49%), Gaps = 108/730 (14%)

Query: 29   GLPGPPGPPG--PPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK----PGKPGEAGLPGLP 82
            G  GPPGPPG  P G  G  G  G  G PG PG PGPKG PGK    PG PG  GLPG P
Sbjct: 598  GDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSP 657

Query: 83   GVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPG 142
            G  G  G  G PG  G PG  G  G  G PG+G    PGPPG  GV G PG +G  G PG
Sbjct: 658  GFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIG---FPGPPGPKGVDGLPGDMGPPGTPG 714

Query: 143  PSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKG--- 199
              G  GLPG PG  G  G PGV   G   L       PG PG PG PG KG  G  G   
Sbjct: 715  RPGFNGLPGNPGVQGQKGEPGVGLPGLKGL-------PGLPGIPGTPGEKGSIGVPGVPG 767

Query: 200  EQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPG 259
            E G +G  G +G  G PGP GLPGSVG  G  G+ G PG  GPPG +GP G  GPPGI G
Sbjct: 768  EHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLSGPPGIKG 826

Query: 260  A-----------PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAG---------PSGE 299
                        PG  GD+G +G  G  G  G  G PG +G PG+ G           G 
Sbjct: 827  EKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGT 886

Query: 300  PGMPGKDGQNGVPGLDGQKGE------AGRNGAPGEKGPNGLPGLPGRAGS--------- 344
            PG PG  G  G PGL G+KG+      +G  G PG KG  G  GLPG+ GS         
Sbjct: 887  PGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSM 946

Query: 345  ---KGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV 401
               KG++GE+G+ G +GE G  G+PG PG  G  G+ G+ G  G  G  G  G PGAPG+
Sbjct: 947  KGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGL 1006

Query: 402  RGFQGQKGSMG---------DPGLPGPQG---LRGDVGDRGPGGAAGP-----------K 438
             G +G  G MG          PG+PGPQG   L GD G +G  G AGP           K
Sbjct: 1007 PGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEK 1066

Query: 439  GDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPL 498
            GDQGIAG  G PG+KGE G  G+ G  G  G +G  G  G  G  G  G +G  G PG  
Sbjct: 1067 GDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPG-- 1124

Query: 499  GLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGP 558
             L G+PGV G  G PG PG      +     G   S+ I   A    +P  PG  G PG 
Sbjct: 1125 -LDGIPGVKGEAGLPGTPGPTGPAGQK----GEPGSDGIPGSAGEKGEPGLPGR-GFPGF 1178

Query: 559  AGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQ 618
             G  G  G  G +G PG  G PG  G  GE G  GP G QG  G  G+ G   +GP+GD+
Sbjct: 1179 PGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDR 1238

Query: 619  GPQGPQGVPGT-------------------SKDGQDGAPGEPGPPGDPGLPGAIGAQGTP 659
            GPQG  G+PG                       G  GAPG PGP GDPG  G  G  G+P
Sbjct: 1239 GPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSP 1298

Query: 660  GICDTSACQG 669
            GI  +    G
Sbjct: 1299 GITGSKGDMG 1308



 Score =  500 bits (1287), Expect = e-141
 Identities = 316/727 (43%), Positives = 361/727 (49%), Gaps = 113/727 (15%)

Query: 28  VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGL 87
           +G PG  GP GP G PGQ G  GE   PGLPG  G +G PG  G PG  GLPG+PG DG 
Sbjct: 60  IGFPGMQGPEGPQGPPGQKGDTGE---PGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGP 116

Query: 88  TGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGI------------ 135
            G  G PG  G  GERG LGPPG PG  G   PGPPG  G+ G PG I            
Sbjct: 117 PGPPGIPGCNGTKGERGPLGPPGLPGFAGN--PGPPGLPGMKGDPGEILGHVPGMLLKGE 174

Query: 136 ----GLRGPPGPSGLPGL---------PGPPGPPGPPGHPGVLPEGATDLQCP--SICPP 180
               G+ G PGP GLPGL          GPPGPPGPPG PG   +     Q P       
Sbjct: 175 RGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQ 234

Query: 181 GPPGPPGMPG-----FKGPTGYKGEQGEVGKD--------GEKGDPGPPGPAGLPGSVGL 227
           G  GPPG+PG      KG    KGE+G+ G+         GEKG+PG PGP G PG  G 
Sbjct: 235 GVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGD 294

Query: 228 QGPRGLRGLPGPLGPP---GDRGPIGFRGPPGIPGAPG---KAGDRGERGPEGFRGPKGD 281
           +G +G  G PG  G P   G +GP G +G  G PG PG     G  GE+G  G+ G  G 
Sbjct: 295 KGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGP 354

Query: 282 LGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEK--GPNGLPGLP 339
            G PGPKG PG+ G  G PG+P   GQ G PG  G++GE G  G PG    GP+G  GLP
Sbjct: 355 RGEPGPKGFPGLPGQPGPPGLP-VPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLP 413

Query: 340 GRAGSKGEKGERGRAGEL-----GEAGPSGEPGVPGDAGMPGERGEAGHRGSA------- 387
           G  GS G  G+ G    +     G  G  G PG+PG  G  GE GE G +G +       
Sbjct: 414 GPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDID 473

Query: 388 GALGPQGPPGAPGVRGFQGQKGSMGDPGL---------PGPQGLRGDVGDRGPGGAAGP- 437
           G  GP GP G PG  GF GQ G+ GD GL         PGPQG  G +G  G  G  G  
Sbjct: 474 GYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEF 533

Query: 438 ------KGDQGIAGSDGLPGDKGELGP------SGLVGPKGESGS---RGELGPKGTQGP 482
                 KGD+G  G  G PG  G  G        GL GPKG  GS   +GE GP G  G 
Sbjct: 534 YFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGF 593

Query: 483 NGTSGVQGVPGPP-----GPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQI 537
            G+ G  G PGPP     GP+G +G  G PG  G PG+PG +    +I  L G   +E +
Sbjct: 594 PGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGL 653

Query: 538 AQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGN 597
                       PGS G PGP G  G PG PG  G PG +G  G  G  G  G PGP+G 
Sbjct: 654 ------------PGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG-IGFPGPPGPKGV 700

Query: 598 QGDRGDKGAAGA----GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAI 653
            G  GD G  G     G +G  G+ G QG +G PG    G  G PG PG PG PG  G+I
Sbjct: 701 DGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSI 760

Query: 654 GAQGTPG 660
           G  G PG
Sbjct: 761 GVPGVPG 767



 Score =  498 bits (1281), Expect = e-140
 Identities = 320/752 (42%), Positives = 365/752 (48%), Gaps = 128/752 (17%)

Query: 24   GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK---PGKPGEAGLPG 80
            G   VG  G PG PGP GKPG+DG  GE G PG PG PG  G  G+    G+ GEAG PG
Sbjct: 270  GMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPG 329

Query: 81   LPGV---------------DGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGE 125
             PG+                G  G  G PGPKG PG  G  GPPG P  G  G PG PGE
Sbjct: 330  PPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGE 389

Query: 126  AGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGP 185
             G  G  G  G    PGPSG  GLPGPPG PGPPG PG    G  + Q       GPPG 
Sbjct: 390  RGEKGDRGFPG-TSLPGPSGRDGLPGPPGSPGPPGQPG-YTNGIVECQPGPPGDQGPPGI 447

Query: 186  PGMPGFKGPTGYKGEQGEV-------GKDGEKGDPGPPGPAGLPGSVGLQGPRGL----- 233
            PG PGF G  G KG++GE        G  G  G  GPPG  G PG  G +G RGL     
Sbjct: 448  PGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDG 507

Query: 234  -RGLPGPLGPP----------------------GDRGPIGFRGPPGI------------- 257
              G+PGP G P                      GD+G  GF G PG+             
Sbjct: 508  VAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHP 567

Query: 258  -----PGAPGKAGDRGERGPE---GFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQN 309
                  G+PG  G +GERGP    GF G +GD G PGP G  G AGP G+ G  G  G  
Sbjct: 568  GLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGP 626

Query: 310  GVPGLDGQKGEAGR----------------NGAPGEKGPNGLPGLPGRAGSKGEKGERGR 353
            G PGL G KGE G+                 G PG +G  G PG PGR G  GEKG  G+
Sbjct: 627  GSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQ 686

Query: 354  --AGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSM 411
               G  G  GP G  G+PGD G PG  G  G  G  G  G QG  G PGV G  G KG  
Sbjct: 687  PGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV-GLPGLKGLP 745

Query: 412  GDPGLPGPQGLRGDVGDRG-PG--GAAGPKGDQGIAGSDGLPGDKGELGPSGL--VGPKG 466
            G PG+PG  G +G +G  G PG  GA GP G QGI G  G PG  G +G  G+  +GP G
Sbjct: 746  GLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPG 805

Query: 467  ESGSRGELGPKGTQGPNGTSGVQGVPG-----PPGPLGLQGVPGVPGITGKPGVPGKEAS 521
              G  G  GP G  GP G  G +G PG      PGP G +G  G+PGITG+ G+PG    
Sbjct: 806  ARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQ 865

Query: 522  EQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGP-- 579
            +       G             +     PG  G PGP G PG PG  G  G PG+ GP  
Sbjct: 866  Q-------GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRG 918

Query: 580  -PGYRGPTGELGDPGPRGN---------QGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGT 629
             PG +G  G++G PG  G+         +G +GD+G  G    GP G++G +G  G PG 
Sbjct: 919  DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQ--IGPIGEKGSRGDPGTPGV 976

Query: 630  -SKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
              KDGQ G PG+PGP GDPG+ G  GA G PG
Sbjct: 977  PGKDGQAGQPGQPGPKGDPGISGTPGAPGLPG 1008



 Score =  497 bits (1279), Expect = e-140
 Identities = 314/755 (41%), Positives = 363/755 (48%), Gaps = 151/755 (20%)

Query: 27   RVGLPGPPGP--------PGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK------ 72
            R GLPG  G         PGPPG  G DG+ G+ GPPG PG PG  G PG PG       
Sbjct: 674  RPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGE 733

Query: 73   -----PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAG 127
                 PG  GLPGLPG+ G  G  G  G  G PGE G++GPPG  G+ G+  PGPPG  G
Sbjct: 734  PGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGE--PGPPGLPG 791

Query: 128  VSGPPG--GIG---LRGPPGPSGLPGLPGPPGPPGPPGHPGVL------PEGATDLQ-CP 175
              G PG  GIG    RGPPG  G PGL GPPG  G  G PG        P+G    Q  P
Sbjct: 792  SVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLP 851

Query: 176  SIC-PPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLR 234
             I    G PG PG  G  G  G+ G +GE+G  G  G PG PGP G PG  G +G  G  
Sbjct: 852  GITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFP 911

Query: 235  GLPGPLGPPG---DRGPIGF------------------------------------RGPP 255
            G  GP G PG   D+G +G                                     RG P
Sbjct: 912  GSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDP 971

Query: 256  GIPGAPGK---AGDRGERGPE------------GFRGPKGDL------GRPGPKGTPGVA 294
            G PG PGK   AG  G+ GP+            G  GPKG +      G PG KG PG+ 
Sbjct: 972  GTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIP 1031

Query: 295  GPSGEPGMPGKDGQN-----------GVPGLDGQKGEAGRNGAP------GEKGPNGLPG 337
            GP G PG+PG  G             G+PGL G+KG+ G  G P      GEKG  G+PG
Sbjct: 1032 GPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPG 1091

Query: 338  LPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPG 397
            +PG  G KG  G  G  G  G  G  G+ G+PG  G+PG +GEAG  G+ G  GP G  G
Sbjct: 1092 MPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKG 1151

Query: 398  APGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELG 457
             PG  G  G  G  G+PGLPG +G  G  G +G  G+ G  G  G+AGS G+PG KGE G
Sbjct: 1152 EPGSDGIPGSAGEKGEPGLPG-RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210

Query: 458  PSGLVGPKGESGSRGE-----LGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGK 512
              G  GP+G+ G  G       GPKG +GP G  G+ G+PGP GP GL G+ GV G  G 
Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGN 1270

Query: 513  PGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG 572
            PG PG                             P  PG  G PG  G PG  G PG  G
Sbjct: 1271 PGWPG----------------------------APGVPGPKGDPGFQGMPGIGGSPGITG 1302

Query: 573  HPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGP----QGPQGVP 627
              G  GPPG  G  G  G PG +G +GD+GD+G  GA GL GP G  GP    +G  G+P
Sbjct: 1303 SKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLP 1362

Query: 628  G-TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
            G     G  G  G PGP G  G+ G +G  G PGI
Sbjct: 1363 GPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGI 1397



 Score =  449 bits (1156), Expect = e-126
 Identities = 289/689 (41%), Positives = 334/689 (48%), Gaps = 125/689 (18%)

Query: 20   LAAAGAQRVGLPGPPGPP---GPPGKPGQDGIDGEAGPPG-----LPGPPGPKGAPGKPG 71
            + + G   +G PG  GPP   GPPG  G  GI GE G PG     +PGP G KGA G PG
Sbjct: 793  VGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG 852

Query: 72   KPGEAGLPGLPGVDGLTGRDGPPGPK------GAPGERGSLGPPGPPGLGGK-------- 117
              G++GLPGLPG  G  G  G PG K      G PG+ GS GP G PGL G+        
Sbjct: 853  ITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPG 912

Query: 118  -----------------GLPGPP------------------GEAGVSGPPGGIGLRGPPG 142
                             GLPG P                  GE G  GP G  G RG PG
Sbjct: 913  SSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPG 972

Query: 143  PSGLP---GLPGPPGPPGPPGHPGVL-PEGATDLQCP-----SICPPGPPGPPGMPGFKG 193
              G+P   G  G PG PGP G PG+    GA  L  P      +  PG PG  G+PG  G
Sbjct: 973  TPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPG 1032

Query: 194  PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRG 253
            P G  G  G+ G  GEKG  GPPG  G+PG  G +G +G+ G PG  G  G++G IG  G
Sbjct: 1033 PQGSPGLPGDKGAKGEKGQAGPPG-IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPG 1091

Query: 254  PPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPG 313
             PG PG  G  G  G  G  G  G KGD G PG  G PGV G +G PG PG  G      
Sbjct: 1092 MPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGP----- 1146

Query: 314  LDGQKGEAGRNGAPGEKGPNGLPGLPGRA--GSKGEKGERGRAGELGEAGPSGEPGVPGD 371
              GQKGE G +G PG  G  G PGLPGR   G  G KG++G  GE+G  G +G PG+PG 
Sbjct: 1147 -AGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGS 1205

Query: 372  ------AGMPGERGEAGHRGSAG--ALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLR 423
                   G PG +G+ G  GS G    GP+G  G  G  G  G  G MG PGLPG  G++
Sbjct: 1206 KGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVK 1265

Query: 424  GDVGDRG-PG--GAAGPKGD------QGIAGSDGLPGDKGELGPSGLVGPKGESGSRGEL 474
            GD G+ G PG  G  GPKGD       GI GS G+ G KG++GP G+ G +G  G  G  
Sbjct: 1266 GDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQ 1325

Query: 475  GPKGTQGPNGTSGVQGVPGPPGPLG----LQGVPGVPGITGKPGVPGKEASEQRIRELCG 530
            G KG QG  G  G +G+PGPPGP G    ++G PG+PG  G PG+ G +           
Sbjct: 1326 GIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQG---------- 1375

Query: 531  GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELG 590
                            P   G  G  G  G PGPPG PG  G PG +G  G  GPTG  G
Sbjct: 1376 ---------------LPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRG 1420

Query: 591  DPGPRGNQGDRGDKGAAGAGLDGPEGDQG 619
             PGP G  G  G  G  G     P  D G
Sbjct: 1421 FPGPPGPDGLPGSMGPPGT----PSVDHG 1445



 Score =  342 bits (878), Expect = 5e-94
 Identities = 231/560 (41%), Positives = 268/560 (47%), Gaps = 106/560 (18%)

Query: 136 GLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPT 195
           G++G  G  GLPGL G  G PG  G                  P GP GPPG        
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQG------------------PEGPQGPPGQ------- 77

Query: 196 GYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPP 255
             KG+ GE G  G KG  GPPG +G PG+ GL G      +PG  GPPG         PP
Sbjct: 78  --KGDTGEPGLPGTKGTRGPPGASGYPGNPGLPG------IPGQDGPPG---------PP 120

Query: 256 GIPGAPGKAGDRGERGP---EGFRGPKGDLGRPGPKGTPG----------VAGPSGEPGM 302
           GIPG  G  G+RG  GP    GF G  G  G PG KG PG          + G  G PG+
Sbjct: 121 GIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGI 180

Query: 303 PGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKG--ERGRAGELGEA 360
           PG  G  G+PGL G        G PG  GP G PG PG  G KG+ G   +G  G+ G+ 
Sbjct: 181 PGTPGPPGLPGLQGPV------GPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQ 234

Query: 361 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420
           G SG PGVPG A +  E+G+   +G  G  G  G  G PGV    G+KG  G PG  G  
Sbjct: 235 GVSGPPGVPGQAQVQ-EKGDFATKGEKGQKGEPGFQGMPGV----GEKGEPGKPGPRGKP 289

Query: 421 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL---GPSGLVGPKGESGSRGELGPK 477
           G  GD G++G  G  G  G  G+ G  G  G+KGE    GP G+V   G  G +GE G  
Sbjct: 290 GKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYP 349

Query: 478 GTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQI 537
           GT GP G  G +G PG PG  G  G+P VPG  G PG PG E  E+  R   G  +    
Sbjct: 350 GTPGPRGEPGPKGFPGLPGQPGPPGLP-VPGQAGAPGFPG-ERGEKGDRGFPGTSL---- 403

Query: 538 AQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGA-----RGPPGYRGPTGELGDP 592
                       PG  GR G  GPPG PGPPG  G+         GPPG +GP G  G P
Sbjct: 404 ------------PGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQP 451

Query: 593 GPRGNQGDRGDKGAAG--AGLDGPEGDQGPQGP------QGVPGTSKD----GQDGAPGE 640
           G  G  G++G KG +     +DG  G  GPQGP       G PG   D    G+DG  G 
Sbjct: 452 GFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGV 511

Query: 641 PGPPGDPGLPGAIGAQGTPG 660
           PGP G PGL G  GA+G PG
Sbjct: 512 PGPQGTPGLIGQPGAKGEPG 531



 Score =  245 bits (626), Expect = 9e-65
 Identities = 170/428 (39%), Positives = 200/428 (46%), Gaps = 72/428 (16%)

Query: 319 GEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGER 378
           G+   +G  G+KG  GLPGL G  G  G +G  G  G  G+ G +GEPG+PG  G  G  
Sbjct: 37  GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 379 GEAGHRGSAGAL------GPQGPPGAPGVRGFQGQKGSMGDPGL------PGPQGLRGDV 426
           G +G+ G+ G        GP GPPG PG  G +G++G +G PGL      PGP GL G  
Sbjct: 97  GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156

Query: 427 GDRG------PG----GAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGP 476
           GD G      PG    G  G  G  G  G  GLPG +G +GP G  GP G  G  G  G 
Sbjct: 157 GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGE 216

Query: 477 KGT-----QGPNGTSGVQGVPGPPG--------------PLGLQGVPGVPGITGKPGVPG 517
           KG      QGP G  G QGV GPPG                G +G  G PG  G PGV  
Sbjct: 217 KGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGE 276

Query: 518 K-EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGP------AGPPGPPGPPGS 570
           K E  +   R   G    +          +P  PG IGR GP      AGPPGPPG    
Sbjct: 277 KGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIG 336

Query: 571 IGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG------AGLDGPEGDQGPQGPQ 624
            G  G +G  GY G  G  G+PGP+G  G  G  G  G      AG  G  G++G +G +
Sbjct: 337 TGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDR 396

Query: 625 GVPGTS------KDGQDGAPGEPGPPGDPGL--------PGAIGAQGTPGICDTSACQGA 670
           G PGTS      +DG  G PG PGPPG PG         PG  G QG PGI      Q  
Sbjct: 397 GFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGI----PGQPG 452

Query: 671 VLGGVGEK 678
            +G +GEK
Sbjct: 453 FIGEIGEK 460


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  493 bits (1268), Expect = e-139
 Identities = 315/754 (41%), Positives = 365/754 (48%), Gaps = 118/754 (15%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGL-----PGPPGPKGAPGKPGKPGEAG------ 77
            G  G  GPPG PG PG  G  G AGPPG      PG  G +G PG PG PGEAG      
Sbjct: 590  GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELS 649

Query: 78   ----LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPG------PPGLGGKGLPGPPGEAG 127
                +PG PG  G  G  GP GP G PG  G  G PG       PG+ G G PGPPG  G
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 128  VSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGV-LPEGATDLQCPS---------- 176
              G PG  G  G PG  G PGLPG PG PG  G P V +P G      P           
Sbjct: 710  DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 177  ICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPG-----PPGPAGLPGSVGLQGPR 231
            I  PG PG PG PG +G  G +G+ G+ G  GE+G PG     P G  GLPG  GL+G +
Sbjct: 770  IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 232  GLRGLPGPLGPPG----DR-GPIGFRGPPGIPGAPGKAGDRGERG---PEGFRGPKGD-- 281
            G RG  GP G PG    DR G  G  G PGIPG  G+ G  G+RG     G  GP G+  
Sbjct: 830  GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 282  ----------LGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGA----- 326
                      +G PGP G PG  G  G PG+PG  GQ G PG  G++G+ G  G      
Sbjct: 890  VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949

Query: 327  ----------------PGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPG 370
                            PGEKG  G+PG+PG  G KG  G  G  G  G+ G +G PG PG
Sbjct: 950  VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009

Query: 371  DAGMPGER------GEAGHRGSAGALGPQGPPGAPGVRGFQGQKGS-------------- 410
              G+PG        G  G RG+ G  G  G PG PG+ G QG KG               
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069

Query: 411  MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGS 470
             GDPGLPG  G +G++G  GP G  GP G +G  GS G PG  G+ GP G +G K   G 
Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK---GI 1126

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG 530
            +G LGP G +GP G  G  G PGP G  G QG  G+PG  G+ G  G   +    R   G
Sbjct: 1127 KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186

Query: 531  GMISEQIAQLAAHLRKPLAPGSIGRPGPAGP------PGPPGPPGSI--GHPGARGPPGY 582
               ++           P   G++G  GP GP      PGPPG PG+I  G  G RGPPG 
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGS 1246

Query: 583  RGPTGELGDPGPRGNQ--GDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGE 640
            RG  G  G PGP G+   G +GDKG+ G    GP+G  G  G  G PG  + G  G PG 
Sbjct: 1247 RGSPGAPGPPGPPGSHVIGIKGDKGSMGH--PGPKGPPGTAGDMGPPG--RLGAPGTPGL 1302

Query: 641  PGPPGDP---GLPGAIGAQGTPGICDTSACQGAV 671
            PGP GDP   G PG  G +G PG   +    G +
Sbjct: 1303 PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPI 1336



 Score =  493 bits (1268), Expect = e-139
 Identities = 326/793 (41%), Positives = 371/793 (46%), Gaps = 187/793 (23%)

Query: 29   GLPGPPGPPGPPGKPGQDG-------IDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGL 81
            G  G PG PGPPG+ G  G       + G  GPPG PG PGP+G PG PG  G+ G PGL
Sbjct: 628  GTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 82   PGVDGLTGRDG-----PPGPKG------------APGERGSLGPPGPPGL---------- 114
            PG DG  G  G     PPGPKG             PG+ G  G PG PGL          
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 115  --GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDL 172
              GG G PG PGE G SG  G IGL G PG  G PG  G  GP G PG PG  P G  + 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG--PPG--EQ 803

Query: 173  QCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPG-----------PAGL 221
              P  C  GP G  G+PG  G    KG+QG  GK G KGDPG PG             G+
Sbjct: 804  GPPGRCIEGPRGAQGLPGLNG---LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGI 860

Query: 222  PGSVGLQGPRGLRGLPGP---LGPPGDRGPIGFRG---------PPGIPGAPGKAGD--- 266
            PG  G  GP G RG PG    LGPPG+ G IG  G         PPG PG PG+ G    
Sbjct: 861  PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI 920

Query: 267  ---RGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGM------PGKDGQNGVPGLDGQ 317
               +G+RG  G +G +GD G PGP     V G  GEPG+      PG+ G  GVPG+ G 
Sbjct: 921  PGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGL 980

Query: 318  KG---------------EAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAG- 361
            KG               + G  G PGE G  G+PG  G  G  G KG+RG  G  G AG 
Sbjct: 981  KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040

Query: 362  ----------------------------PSGEPGVPGDAGMPGERGEAGHRGSAGALGPQ 393
                                        P+G+PG+PGD G  GE G+ G  G  G  GP+
Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100

Query: 394  GPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGG------AAGPKGDQGIAGSD 447
            G PG+PG  G  G+ G  GD G  G +GL G  G RGP G      + GP G +G  G D
Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRD 1160

Query: 448  GLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVP 507
            G+PG  GE G +GL+  +   G RG  G +G +G  G  G  G+PG  G +G  G  G  
Sbjct: 1161 GIPGPAGEKGETGLL--RAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPT 1218

Query: 508  GITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGP 567
            GI G PG PG          L G +I  Q        R P  PGS G PG  GPPGPPG 
Sbjct: 1219 GIEGFPGPPG----------LPGAIIPGQTGN-----RGP--PGSRGSPGAPGPPGPPGS 1261

Query: 568  --------PGSIGHPGARGPPGYRG---PTGELGDPGPRGNQGDRGDKGAAG-------- 608
                     GS+GHPG +GPPG  G   P G LG PG  G  G RGD G  G        
Sbjct: 1262 HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEK 1321

Query: 609  -----AGLDGPEGDQGPQGPQGV---PGTSK-------------DGQDGAPGEPGPPGDP 647
                  G  GP G  GP+GP GV   PGT K              G+ G  GEPGPPG P
Sbjct: 1322 GNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381

Query: 648  GLPGAIGAQGTPG 660
            G  G  G +G PG
Sbjct: 1382 GNLGPCGPRGKPG 1394



 Score =  476 bits (1225), Expect = e-134
 Identities = 325/753 (43%), Positives = 362/753 (48%), Gaps = 118/753 (15%)

Query: 10  LLLLLLLGELLAAAGAQRVGL----------------PGPPGPPGPPGKPGQDGIDGEAG 53
           +LLL LL  LLAAA A   G                  G  G PGPPG PGQ G     G
Sbjct: 11  VLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGF---TG 67

Query: 54  PPGLPGPPGPKGAPGKPGKPGE------AGLPGL---PGVDGLTGRDGPPGPKGAPGERG 104
           P GLPGP GPKG PG PG  G       +GLPG    PG+ G  G  GP G  G PG  G
Sbjct: 68  PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127

Query: 105 SLGPPGPPGLGGK-GLPGPPGEAGVSGPPGGI--------------GLRGPPGPSGLPG- 148
           S G  G PGL G  G PG PG AG+ G  G                GL G PGP GLPG 
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187

Query: 149 --LPGPPGPPGPP---GHPGVL-PEGATDLQCPSICP----------PGPPGPPG--MPG 190
              PGP GPPGPP   G PG + P G        +             GPPGPPG  +  
Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 191 FKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG-----SVGLQGPRGLRGLPGPLGP--- 242
             GP      +GE G  G  G+PGPPGP+GLPG       G  G  GL+G PG  G    
Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307

Query: 243 PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGP---------KGDLGR---PGPKGT 290
           PG  G  G RG PG+ G  G  G +G+ GP GFRGP         KGD G    PGP+G 
Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367

Query: 291 PGVAGPSGEPGMPGKDGQN-----GVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G  GPSG PG+PG  G +     G PG  G KG  G  G PG K   G PG PG AGS 
Sbjct: 368 RGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPGCAGSP 426

Query: 346 GEKGERGRAGELGE----AGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP--PGAP 399
           G  G  G  G  G+     GP G+ G+PG  G PG  G  G +G  G L  Q P  PG P
Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486

Query: 400 GVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE-LGP 458
           G+ G  G  G  G PG  G  GL+G  G  G  G  G  G  G  G  GL G+KGE L P
Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546

Query: 459 SGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK 518
            G VG  G+ G RG+ G KG  G  GT GV+G+PGP G L L G  G  G  G PG PG 
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606

Query: 519 EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP----------PGPPGPP 568
                       G   E   Q    +     PG+ G PG AGP          PGPPGPP
Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGV-----PGAPGPPGEAGPRGELSVSTPVPGPPGPP 661

Query: 569 GSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPG 628
           G  GHPG +GPPG  G  G+ GDP   G  G  G+ G  G G  GP    GP+G QG PG
Sbjct: 662 GPPGHPGPQGPPGIPGSLGKCGDP---GLPGPDGEPGIPGIGFPGP---PGPKGDQGFPG 715

Query: 629 TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
           T   G  G PG+ G PG PG PG  GA+G P +
Sbjct: 716 TK--GSLGCPGKMGEPGLPGKPGLPGAKGEPAV 746



 Score =  449 bits (1155), Expect = e-126
 Identities = 288/702 (41%), Positives = 336/702 (47%), Gaps = 114/702 (16%)

Query: 19   LLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPG---------PKGAPGK 69
            L  A G   V +PG PG PG PG+ G  G  GE G PGLPG PG         P+G PG+
Sbjct: 737  LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQ 796

Query: 70   PGKPGEAGLPG--LPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAG 127
            PG PGE G PG  + G  G  G  G  G KG  G RG  GP G PG+ G    G PGE G
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 128  VSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPG 187
              G PG  G  GP G  G PG PG  GPPG  G  G++          +I PPGPPG PG
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG------AIGPPGPPGNPG 910

Query: 188  MPGFKGPTGY---KGEQGEVGKDGEKGDPGPPGP------------------AGLPGSVG 226
             PG +G  G    KG++G  G  GE+GD G PGP                  AG PG  G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 227  ------LQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKG 280
                  + G +GL+GLPGP GPPG RG +G  G PG PG  G  G  G  G  G +G +G
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 281  DLGRPGPKGTPGVAG-----------------------PSGEPGMPG---KDGQNGVPGL 314
             LG PG  G PG+ G                       P+G+PG+PG   K G+ G PG 
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 315  DGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGM 374
             G  G AG  GAPG  G  GLPG PG  G  G KG +G  G  G  GP G PG PG  G 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 375  PGERGEAGHRGSAGALG----------PQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG 424
             G RG+ G  G  G  G          P GP G PG +G +G +G+ G PGLPG +G  G
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 425  DVGDRGPGGAAG--------------PKGDQGIAGSDGLPGDKGELGPSG--LVGPKGES 468
            D G RGP G  G                G++G  GS G PG  G  GP G  ++G KG+ 
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 469  GSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIREL 528
            GS G  GPKG  G  G  G  G  G PG  GL G  G PG  G PGV G++ +   +  +
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 529  CGGMISEQIAQLAAHLRKPLAPGS---IGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGP 585
              G       +    +R    PG+   I  PG  GPPG PG PG  G PG  GPPG  GP
Sbjct: 1331 --GPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGP 1386

Query: 586  TGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVP 627
             G  G PG  G             G  GP G++G +G +G P
Sbjct: 1387 CGPRGKPGKDGK-----------PGTPGPAGEKGNKGSKGEP 1417



 Score =  331 bits (848), Expect = 2e-90
 Identities = 224/565 (39%), Positives = 259/565 (45%), Gaps = 105/565 (18%)

Query: 181 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240
           G  G  G  GF GP G  G++G  G +G  G  GP G  GLPG  G +G RG+ GLPG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300
           G PG  G  G  GP G+ G PG +G +GE   +GF G  G LG PG    PG AG  G+ 
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGE---QGFPGLPGTLGYPG---IPGAAGLKGQK 156

Query: 301 GMPGKDGQ-----NGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAG 355
           G P K+        G PGL G  G  G  G PG  GP G PG PG  G  G  G RG  G
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 356 ELGEA--GPSGEPGVPGDAGMPGERGEA--------------GHRGSAGALGPQGPPGAP 399
            +GE   G  GE GV G  G PG  G                G +G  GA+G  GPPG  
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 400 GVRG--FQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELG 457
           G+ G  +  +KG+ GDPGL G  G  G  G  G  G  G +G  G+ G DG+ G KG++G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 458 PSGLVGP---------KGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPL--GLQGVPGV 506
           P G  GP         KG+ G+ G  GP+G +GP G SG  GVPG PG    GL+G PG 
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 507 PGITGKPGV---PGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPG 563
           PG+ G  G    PGK+A                       +  P +PG  G PG  G PG
Sbjct: 397 PGLKGSKGERGRPGKDA-----------------------MGTPGSPGCAGSPGLPGSPG 433

Query: 564 PPGPPGSI----GHPGARGPPGYRGPTGELGDPGPRGNQGD------------------- 600
           PPGPPG I    G PG  G PGY G  G  G  GP+G  G                    
Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 601 -RGDKGAAG----AGLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGP----------P 644
             G KG  G    AGL G  G  G  G  G PG     G  G  GE G           P
Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553

Query: 645 GDPGLPGAIGAQGTPGICDTSACQG 669
           GDPGL G  G +G  GI  T   +G
Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKG 578



 Score =  272 bits (695), Expect = 9e-73
 Identities = 185/486 (38%), Positives = 222/486 (45%), Gaps = 78/486 (16%)

Query: 247 GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKD 306
           G  G +G  G PG PG  G +G  GPEG  GP+G      PKG PG+      PG+ G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQG------PKGFPGL------PGLTGSK 90

Query: 307 GQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEP 366
           G  G+ GL G  G  G  G PG  GP GL G+PG +GSKGE+G  G  G LG  G  G  
Sbjct: 91  GVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150

Query: 367 GVPGDAGMPGE--------RGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPG 418
           G+ G  G P +        +G+ G  G+ G  G  GPPG PG  G  G  G  G PG  G
Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMG 210

Query: 419 PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL-----GPSGLVGPKGESGSRGE 473
           P+G +G +G+R      G KG++G+ G  G PG  G +     GP      KGE G +G 
Sbjct: 211 PRGPKGHMGER----VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGA 266

Query: 474 LGPKGTQGPNGTSGV-----QGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SEQ 523
           +G  G  GP+G  G      +G PG PG  G  G  GVPG  G  GV G         E 
Sbjct: 267 MGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGED 326

Query: 524 RIRELCGGMISEQIA---------QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG-- 572
            I+   G +               Q       P  PG  G  GP GP GPPG PGS G  
Sbjct: 327 GIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSS 386

Query: 573 HPGARGPPGYRGPTGELGDPGPRGNQ--GDRGDKGAAGA-------GLDGPEGD----QG 619
            PG RG PG+ G  G  G+ G  G    G  G  G AG+       G  GP GD    +G
Sbjct: 387 RPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKG 446

Query: 620 PQGPQGVPG-------TSKDGQDGAPGE--------PGPPGDPGLPGAIGAQGTPGICDT 664
           P G  G+PG          DG  G PG         PGPPG PGLPG  G +G PG    
Sbjct: 447 PPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506

Query: 665 SACQGA 670
           +  +G+
Sbjct: 507 AGLKGS 512



 Score =  262 bits (669), Expect = 9e-70
 Identities = 157/350 (44%), Positives = 175/350 (50%), Gaps = 32/350 (9%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGK---PGQDGIDGEAGPPGLPGPPGPKGAPGKPGKP 73
            GE+        +G  GP G PG PG    PG+ G  G+ G  G+ G  GP G  G PG P
Sbjct: 1083 GEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142

Query: 74   GEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSL-GPPGPPG----LGGKGLPGPPGEAGV 128
            G  G PG  G+ G  GRDG PGP G  GE G L  PPGP G     G KG  G PG  G+
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202

Query: 129  SGPPGGIGLRGPPGPSGLPGLPGPPGPPGP--PGHPGVLPEGATDLQCPSICPPGPPGPP 186
             G  G +G  GP GP+G+ G PGPPG PG   PG  G                 GPPG  
Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG---------------NRGPPGSR 1247

Query: 187  GMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDR 246
            G PG  GP G  G    +G  G+KG  G PGP G PG+ G  GP G  G PG  G PG R
Sbjct: 1248 GSPGAPGPPGPPGSH-VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPR 1306

Query: 247  GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGT------PGVAGPSGEP 300
            G  GF+G PG+ G  G  G  G  GP G  GPKG  G  G  GT      PG  GP G P
Sbjct: 1307 GDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTP 1366

Query: 301  GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGE 350
            G PG  G+ G PG  G  G  G  G PG+ G  G PG  G  G+KG KGE
Sbjct: 1367 GEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 42/102 (41%), Positives = 49/102 (48%), Gaps = 15/102 (14%)

Query: 581 GYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGE 640
           G +G  GE G PGP G+ G +G          GPEG  GPQGP+G PG       G  G 
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKG--------FTGPEGLPGPQGPKGFPGLP-----GLTGS 89

Query: 641 PGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSR 682
            G  G  GLPG  G+ G PG    +   G V  GV   SGS+
Sbjct: 90  KGVRGISGLPGFSGSPGLPGTPGNTGPYGLV--GVPGCSGSK 129



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 29/70 (41%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 603 DKGAAGA-GLDGPEGDQGPQGPQGVPGTSK-DGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
           DKG     G  G +G++G  GP G PG     G +G PG  GP G PGLPG  G++G  G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 661 ICDTSACQGA 670
           I       G+
Sbjct: 95  ISGLPGFSGS 104


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  493 bits (1268), Expect = e-139
 Identities = 315/754 (41%), Positives = 365/754 (48%), Gaps = 118/754 (15%)

Query: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGL-----PGPPGPKGAPGKPGKPGEAG------ 77
            G  G  GPPG PG PG  G  G AGPPG      PG  G +G PG PG PGEAG      
Sbjct: 590  GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELS 649

Query: 78   ----LPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPG------PPGLGGKGLPGPPGEAG 127
                +PG PG  G  G  GP GP G PG  G  G PG       PG+ G G PGPPG  G
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 128  VSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGV-LPEGATDLQCPS---------- 176
              G PG  G  G PG  G PGLPG PG PG  G P V +P G      P           
Sbjct: 710  DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 177  ICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPG-----PPGPAGLPGSVGLQGPR 231
            I  PG PG PG PG +G  G +G+ G+ G  GE+G PG     P G  GLPG  GL+G +
Sbjct: 770  IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 232  GLRGLPGPLGPPG----DR-GPIGFRGPPGIPGAPGKAGDRGERG---PEGFRGPKGD-- 281
            G RG  GP G PG    DR G  G  G PGIPG  G+ G  G+RG     G  GP G+  
Sbjct: 830  GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 282  ----------LGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGA----- 326
                      +G PGP G PG  G  G PG+PG  GQ G PG  G++G+ G  G      
Sbjct: 890  VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949

Query: 327  ----------------PGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPG 370
                            PGEKG  G+PG+PG  G KG  G  G  G  G+ G +G PG PG
Sbjct: 950  VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009

Query: 371  DAGMPGER------GEAGHRGSAGALGPQGPPGAPGVRGFQGQKGS-------------- 410
              G+PG        G  G RG+ G  G  G PG PG+ G QG KG               
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069

Query: 411  MGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGS 470
             GDPGLPG  G +G++G  GP G  GP G +G  GS G PG  G+ GP G +G K   G 
Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK---GI 1126

Query: 471  RGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCG 530
            +G LGP G +GP G  G  G PGP G  G QG  G+PG  G+ G  G   +    R   G
Sbjct: 1127 KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186

Query: 531  GMISEQIAQLAAHLRKPLAPGSIGRPGPAGP------PGPPGPPGSI--GHPGARGPPGY 582
               ++           P   G++G  GP GP      PGPPG PG+I  G  G RGPPG 
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGS 1246

Query: 583  RGPTGELGDPGPRGNQ--GDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGE 640
            RG  G  G PGP G+   G +GDKG+ G    GP+G  G  G  G PG  + G  G PG 
Sbjct: 1247 RGSPGAPGPPGPPGSHVIGIKGDKGSMGH--PGPKGPPGTAGDMGPPG--RLGAPGTPGL 1302

Query: 641  PGPPGDP---GLPGAIGAQGTPGICDTSACQGAV 671
            PGP GDP   G PG  G +G PG   +    G +
Sbjct: 1303 PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPI 1336



 Score =  493 bits (1268), Expect = e-139
 Identities = 326/793 (41%), Positives = 371/793 (46%), Gaps = 187/793 (23%)

Query: 29   GLPGPPGPPGPPGKPGQDG-------IDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGL 81
            G  G PG PGPPG+ G  G       + G  GPPG PG PGP+G PG PG  G+ G PGL
Sbjct: 628  GTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 82   PGVDGLTGRDG-----PPGPKG------------APGERGSLGPPGPPGL---------- 114
            PG DG  G  G     PPGPKG             PG+ G  G PG PGL          
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 115  --GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDL 172
              GG G PG PGE G SG  G IGL G PG  G PG  G  GP G PG PG  P G  + 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG--PPG--EQ 803

Query: 173  QCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPG-----------PAGL 221
              P  C  GP G  G+PG  G    KG+QG  GK G KGDPG PG             G+
Sbjct: 804  GPPGRCIEGPRGAQGLPGLNG---LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGI 860

Query: 222  PGSVGLQGPRGLRGLPGP---LGPPGDRGPIGFRG---------PPGIPGAPGKAGD--- 266
            PG  G  GP G RG PG    LGPPG+ G IG  G         PPG PG PG+ G    
Sbjct: 861  PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI 920

Query: 267  ---RGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGM------PGKDGQNGVPGLDGQ 317
               +G+RG  G +G +GD G PGP     V G  GEPG+      PG+ G  GVPG+ G 
Sbjct: 921  PGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGL 980

Query: 318  KG---------------EAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAG- 361
            KG               + G  G PGE G  G+PG  G  G  G KG+RG  G  G AG 
Sbjct: 981  KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040

Query: 362  ----------------------------PSGEPGVPGDAGMPGERGEAGHRGSAGALGPQ 393
                                        P+G+PG+PGD G  GE G+ G  G  G  GP+
Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100

Query: 394  GPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGG------AAGPKGDQGIAGSD 447
            G PG+PG  G  G+ G  GD G  G +GL G  G RGP G      + GP G +G  G D
Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRD 1160

Query: 448  GLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVP 507
            G+PG  GE G +GL+  +   G RG  G +G +G  G  G  G+PG  G +G  G  G  
Sbjct: 1161 GIPGPAGEKGETGLL--RAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPT 1218

Query: 508  GITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGP 567
            GI G PG PG          L G +I  Q        R P  PGS G PG  GPPGPPG 
Sbjct: 1219 GIEGFPGPPG----------LPGAIIPGQTGN-----RGP--PGSRGSPGAPGPPGPPGS 1261

Query: 568  --------PGSIGHPGARGPPGYRG---PTGELGDPGPRGNQGDRGDKGAAG-------- 608
                     GS+GHPG +GPPG  G   P G LG PG  G  G RGD G  G        
Sbjct: 1262 HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEK 1321

Query: 609  -----AGLDGPEGDQGPQGPQGV---PGTSK-------------DGQDGAPGEPGPPGDP 647
                  G  GP G  GP+GP GV   PGT K              G+ G  GEPGPPG P
Sbjct: 1322 GNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381

Query: 648  GLPGAIGAQGTPG 660
            G  G  G +G PG
Sbjct: 1382 GNLGPCGPRGKPG 1394



 Score =  484 bits (1246), Expect = e-136
 Identities = 329/849 (38%), Positives = 390/849 (45%), Gaps = 199/849 (23%)

Query: 29   GLPGPPGPPGPPGK-------PGQDGIDGEAGPPGLPGPPGPKGAPGK--------PGKP 73
            GLPG PGPPGPPG        PG  G+ G  G PG+PG  GPKG PG         PG P
Sbjct: 427  GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486

Query: 74   GEAGLPGLPGVDGLTGRDGPPGPKGAPGE------------------------------- 102
            G  GLPGL GV G+ GR G  G KG+PG                                
Sbjct: 487  GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546

Query: 103  RGSLGPPGPPGLGGK-------GLPGPPGEAGVSGPPGGIGL------RGPPGPSGLPGL 149
             G +G PG PGL G+       G+PG PG  G+ GP G + L      +GPPG  G PG 
Sbjct: 547  EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606

Query: 150  PGPPGPPGPPGH-----PGVL----------------PEGATDLQCPSICPPGPPGPPGM 188
            PGP GP GPPG+     PG+                 P G   +  P   PPGPPGPPG 
Sbjct: 607  PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGH 666

Query: 189  PGFKGPTGYKGEQGEVGK------DGEKGDPG-----PPGPAG------LPGSVGLQGPR 231
            PG +GP G  G  G+ G       DGE G PG     PPGP G        GS+G  G  
Sbjct: 667  PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKM 726

Query: 232  GLRGLPGPLGPPGDRGP--IGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPG--- 286
            G  GLPG  G PG +G   +   G PG PG PG+ G+ GE G  G  G  G  G PG   
Sbjct: 727  GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG 786

Query: 287  ---PKGTPGVAGPSGEPGMPGK-----DGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGL 338
               P+G PG  GP GE G PG+      G  G+PGL+G KG+ GR G  G KG  G+PGL
Sbjct: 787  LDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGL 846

Query: 339  PGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGM---PGERGEAGHRGSAGALGPQGP 395
              R+G  GE G  G  G  GE GP G+ G PG+ G+   PGE G  G  G  GA+GP GP
Sbjct: 847  D-RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905

Query: 396  PGAPGV---------------RGFQGQKGSMGDPGLPGPQGLRGDVGDRG-PG-----GA 434
            PG PG                RG  G KG  GD G PGP  +   +GD+G PG     G 
Sbjct: 906  PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965

Query: 435  AGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGP 494
             G KG++G+ G  GL G KG  GP+G  GP+G+ GS G  G  G +G  G+ G  G+PG 
Sbjct: 966  PGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025

Query: 495  ---------PGPLGLQGVPGVPGITGKPGVPG-KEASEQRIRELCGGMISEQIAQLAAHL 544
                     PG  G  G+PG+ G+ G  G PG  E +        G             +
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 545  RKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARG------------PPGYRGPTGELGDP 592
             +P  PG +G  GP G PG PG PG  G PG  G            PPG RGP G  G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 593  GPRGNQGDRGDKGAAGAGLDGPEGDQG-------PQGPQGVPGTS----KDGQDGAPGEP 641
            G  G  G RGD+G  G  + GP G++G       P GP+G PG        G  G PG P
Sbjct: 1146 GSPGPMGIRGDQGRDG--IPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLP 1203

Query: 642  GP------------------PGDPGLPGAI-----------GAQGTPGICDTSACQGAVL 672
            G                   PG PGLPGAI           G++G+PG        G+ +
Sbjct: 1204 GRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHV 1263

Query: 673  GGVGEKSGS 681
             G+    GS
Sbjct: 1264 IGIKGDKGS 1272



 Score =  482 bits (1240), Expect = e-136
 Identities = 308/744 (41%), Positives = 354/744 (47%), Gaps = 124/744 (16%)

Query: 19   LLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPG---------PKGAPGK 69
            L  A G   V +PG PG PG PG+ G  G  GE G PGLPG PG         P+G PG+
Sbjct: 737  LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQ 796

Query: 70   PGKPGEAGLPG--LPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAG 127
            PG PGE G PG  + G  G  G  G  G KG  G RG  GP G PG+ G    G PGE G
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 128  VSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPG 187
              G PG  G  GP G  G PG PG  GPPG  G  G++          +I PPGPPG PG
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG------AIGPPGPPGNPG 910

Query: 188  MPGFKGPTGY---KGEQGEVGKDGEKGDPGPPGP------------------AGLPGSVG 226
             PG +G  G    KG++G  G  GE+GD G PGP                  AG PG  G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 227  ------LQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKG 280
                  + G +GL+GLPGP GPPG RG +G  G PG PG  G  G  G  G  G +G +G
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 281  DLGRPGPKGTPGVAG-----------------------PSGEPGMPG---KDGQNGVPGL 314
             LG PG  G PG+ G                       P+G+PG+PG   K G+ G PG 
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 315  DGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGM 374
             G  G AG  GAPG  G  GLPG PG  G  G KG +G  G  G  GP G PG PG  G 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 375  PGERGEAGHRGSAGALG----------PQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRG 424
             G RG+ G  G  G  G          P GP G PG +G +G +G+ G PGLPG +G  G
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 425  DVGDRGPGGAAGPKGDQGI--------AGSDGLPGDKGELGPSGLVGPKGES--GSRGEL 474
            D G RGP G  G  G  G+         G+ G PG +G  G  G  GP G    G +G+ 
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 475  GPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMIS 534
            G  G  GP G  G  G  GPPG LG  G PG+PG  G PG  G             G+  
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFP-----------GVKG 1319

Query: 535  EQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGH------PGARGPPGYRGPTGE 588
            E+          P   GSIG PGP GP GPPG  G  G       PG+ GPPG  G  G 
Sbjct: 1320 EK--------GNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGM 1371

Query: 589  LGDPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDP 647
             G+PGP G  G+ G  G  G  G DG  G  GP G +G          G+ GEPGP G  
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG--------NKGSKGEPGPAGSD 1423

Query: 648  GLPGAIGAQGTPGICDTSACQGAV 671
            GLPG  G +G  G   T   +G V
Sbjct: 1424 GLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  476 bits (1225), Expect = e-134
 Identities = 325/753 (43%), Positives = 362/753 (48%), Gaps = 118/753 (15%)

Query: 10  LLLLLLLGELLAAAGAQRVGL----------------PGPPGPPGPPGKPGQDGIDGEAG 53
           +LLL LL  LLAAA A   G                  G  G PGPPG PGQ G     G
Sbjct: 11  VLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGF---TG 67

Query: 54  PPGLPGPPGPKGAPGKPGKPGE------AGLPGL---PGVDGLTGRDGPPGPKGAPGERG 104
           P GLPGP GPKG PG PG  G       +GLPG    PG+ G  G  GP G  G PG  G
Sbjct: 68  PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127

Query: 105 SLGPPGPPGLGGK-GLPGPPGEAGVSGPPGGI--------------GLRGPPGPSGLPG- 148
           S G  G PGL G  G PG PG AG+ G  G                GL G PGP GLPG 
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187

Query: 149 --LPGPPGPPGPP---GHPGVL-PEGATDLQCPSICP----------PGPPGPPG--MPG 190
              PGP GPPGPP   G PG + P G        +             GPPGPPG  +  
Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 191 FKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG-----SVGLQGPRGLRGLPGPLGP--- 242
             GP      +GE G  G  G+PGPPGP+GLPG       G  G  GL+G PG  G    
Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307

Query: 243 PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGP---------KGDLGR---PGPKGT 290
           PG  G  G RG PG+ G  G  G +G+ GP GFRGP         KGD G    PGP+G 
Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367

Query: 291 PGVAGPSGEPGMPGKDGQN-----GVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSK 345
            G  GPSG PG+PG  G +     G PG  G KG  G  G PG K   G PG PG AGS 
Sbjct: 368 RGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPGCAGSP 426

Query: 346 GEKGERGRAGELGE----AGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP--PGAP 399
           G  G  G  G  G+     GP G+ G+PG  G PG  G  G +G  G L  Q P  PG P
Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486

Query: 400 GVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE-LGP 458
           G+ G  G  G  G PG  G  GL+G  G  G  G  G  G  G  G  GL G+KGE L P
Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546

Query: 459 SGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGK 518
            G VG  G+ G RG+ G KG  G  GT GV+G+PGP G L L G  G  G  G PG PG 
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606

Query: 519 EASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGP----------PGPPGPP 568
                       G   E   Q    +     PG+ G PG AGP          PGPPGPP
Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGV-----PGAPGPPGEAGPRGELSVSTPVPGPPGPP 661

Query: 569 GSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPG 628
           G  GHPG +GPPG  G  G+ GDP   G  G  G+ G  G G  GP    GP+G QG PG
Sbjct: 662 GPPGHPGPQGPPGIPGSLGKCGDP---GLPGPDGEPGIPGIGFPGP---PGPKGDQGFPG 715

Query: 629 TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661
           T   G  G PG+ G PG PG PG  GA+G P +
Sbjct: 716 TK--GSLGCPGKMGEPGLPGKPGLPGAKGEPAV 746



 Score =  331 bits (848), Expect = 2e-90
 Identities = 224/565 (39%), Positives = 259/565 (45%), Gaps = 105/565 (18%)

Query: 181 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240
           G  G  G  GF GP G  G++G  G +G  G  GP G  GLPG  G +G RG+ GLPG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300
           G PG  G  G  GP G+ G PG +G +GE   +GF G  G LG PG    PG AG  G+ 
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGE---QGFPGLPGTLGYPG---IPGAAGLKGQK 156

Query: 301 GMPGKDGQ-----NGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAG 355
           G P K+        G PGL G  G  G  G PG  GP G PG PG  G  G  G RG  G
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 356 ELGEA--GPSGEPGVPGDAGMPGERGEA--------------GHRGSAGALGPQGPPGAP 399
            +GE   G  GE GV G  G PG  G                G +G  GA+G  GPPG  
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 400 GVRG--FQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELG 457
           G+ G  +  +KG+ GDPGL G  G  G  G  G  G  G +G  G+ G DG+ G KG++G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 458 PSGLVGP---------KGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPL--GLQGVPGV 506
           P G  GP         KG+ G+ G  GP+G +GP G SG  GVPG PG    GL+G PG 
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 507 PGITGKPGV---PGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPG 563
           PG+ G  G    PGK+A                       +  P +PG  G PG  G PG
Sbjct: 397 PGLKGSKGERGRPGKDA-----------------------MGTPGSPGCAGSPGLPGSPG 433

Query: 564 PPGPPGSI----GHPGARGPPGYRGPTGELGDPGPRGNQGD------------------- 600
           PPGPPG I    G PG  G PGY G  G  G  GP+G  G                    
Sbjct: 434 PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 601 -RGDKGAAG----AGLDGPEGDQGPQGPQGVPG-TSKDGQDGAPGEPGP----------P 644
             G KG  G    AGL G  G  G  G  G PG     G  G  GE G           P
Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553

Query: 645 GDPGLPGAIGAQGTPGICDTSACQG 669
           GDPGL G  G +G  GI  T   +G
Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKG 578



 Score =  328 bits (840), Expect = 1e-89
 Identities = 212/472 (44%), Positives = 231/472 (48%), Gaps = 60/472 (12%)

Query: 17   GELLAAAGAQRVGLPGPPGPPGPPGKPGQD------GIDGEAGPPGLP---GPPGPKGAP 67
            G+L +       GL G PG  G  G PG        G  G AG PGLP   G  G KG P
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 68   G-----KPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGP 122
            G     +PG PG  G PGLPG  G  G  G PGP G  G  G  G PG P  G  GLPG 
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSP--GSPGLPGK 1114

Query: 123  PGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGP 182
            PG  G  G  G  GL GPPG  G PGLPG PG PGP G  G   +G   +       PGP
Sbjct: 1115 PGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG--DQGRDGI-------PGP 1165

Query: 183  PGPPGMPGF----KGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPG 238
             G  G  G      GP G  G QG  G  G  G PG PG  G  G  G +GP G+ G PG
Sbjct: 1166 AGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 239  PLGPPGD--RGPIGFRGPPGIPGAPGKAGDRGERGPE--GFRGPKGDLGRPGPKGTPGVA 294
            P G PG    G  G RGPPG  G+PG  G  G  G    G +G KG +G PGPKG PG A
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTA 1285

Query: 295  GPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGL------PGRAGSKGEK 348
               G+ G PG+ G  G PGL G +G+ G  G PG KG  G PG       PG  G KG  
Sbjct: 1286 ---GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342

Query: 349  GERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQK 408
            G RG  G L      G PG PG  G PG +GE G  G  G LGP GP G P         
Sbjct: 1343 GVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP--------- 1393

Query: 409  GSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG 460
            G  G PG PGP G +G+          G KG+ G AGSDGLPG KG+ G SG
Sbjct: 1394 GKDGKPGTPGPAGEKGN---------KGSKGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  272 bits (695), Expect = 9e-73
 Identities = 185/486 (38%), Positives = 222/486 (45%), Gaps = 78/486 (16%)

Query: 247 GPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKD 306
           G  G +G  G PG PG  G +G  GPEG  GP+G      PKG PG+      PG+ G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQG------PKGFPGL------PGLTGSK 90

Query: 307 GQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEP 366
           G  G+ GL G  G  G  G PG  GP GL G+PG +GSKGE+G  G  G LG  G  G  
Sbjct: 91  GVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150

Query: 367 GVPGDAGMPGE--------RGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPG 418
           G+ G  G P +        +G+ G  G+ G  G  GPPG PG  G  G  G  G PG  G
Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMG 210

Query: 419 PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGEL-----GPSGLVGPKGESGSRGE 473
           P+G +G +G+R      G KG++G+ G  G PG  G +     GP      KGE G +G 
Sbjct: 211 PRGPKGHMGER----VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGA 266

Query: 474 LGPKGTQGPNGTSGV-----QGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA-----SEQ 523
           +G  G  GP+G  G      +G PG PG  G  G  GVPG  G  GV G         E 
Sbjct: 267 MGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGED 326

Query: 524 RIRELCGGMISEQIA---------QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIG-- 572
            I+   G +               Q       P  PG  G  GP GP GPPG PGS G  
Sbjct: 327 GIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSS 386

Query: 573 HPGARGPPGYRGPTGELGDPGPRGNQ--GDRGDKGAAGA-------GLDGPEGD----QG 619
            PG RG PG+ G  G  G+ G  G    G  G  G AG+       G  GP GD    +G
Sbjct: 387 RPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKG 446

Query: 620 PQGPQGVPG-------TSKDGQDGAPGE--------PGPPGDPGLPGAIGAQGTPGICDT 664
           P G  G+PG          DG  G PG         PGPPG PGLPG  G +G PG    
Sbjct: 447 PPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506

Query: 665 SACQGA 670
           +  +G+
Sbjct: 507 AGLKGS 512



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 42/102 (41%), Positives = 49/102 (48%), Gaps = 15/102 (14%)

Query: 581 GYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGE 640
           G +G  GE G PGP G+ G +G          GPEG  GPQGP+G PG       G  G 
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKG--------FTGPEGLPGPQGPKGFPGLP-----GLTGS 89

Query: 641 PGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSR 682
            G  G  GLPG  G+ G PG    +   G V  GV   SGS+
Sbjct: 90  KGVRGISGLPGFSGSPGLPGTPGNTGPYGLV--GVPGCSGSK 129



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 29/70 (41%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 603 DKGAAGA-GLDGPEGDQGPQGPQGVPGTSK-DGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660
           DKG     G  G +G++G  GP G PG     G +G PG  GP G PGLPG  G++G  G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 661 ICDTSACQGA 670
           I       G+
Sbjct: 95  ISGLPGFSGS 104


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.147    0.474 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,595,269
Number of Sequences: 37866
Number of extensions: 5784287
Number of successful extensions: 246272
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 808
Number of HSP's successfully gapped in prelim test: 1904
Number of HSP's that attempted gapping in prelim test: 17552
Number of HSP's gapped (non-prelim): 31509
length of query: 684
length of database: 18,247,518
effective HSP length: 109
effective length of query: 575
effective length of database: 14,120,124
effective search space: 8119071300
effective search space used: 8119071300
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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