Guide to the Human Genome
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Search of human proteins with 239750867

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
sapiens]
         (800 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ...  1651   0.0  
gi|239756297 PREDICTED: hypothetical protein [Homo sapiens]           536   e-152
gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo ...   449   e-126
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          72   2e-12
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      71   3e-12
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    70   1e-11
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    70   1e-11
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       69   1e-11
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      69   2e-11
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    69   2e-11
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    69   2e-11
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    69   2e-11
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    67   9e-11
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    67   9e-11
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    67   9e-11
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                66   1e-10
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...    66   1e-10
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...    66   1e-10
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    64   7e-10
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    64   7e-10
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    64   7e-10
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     63   9e-10
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       62   2e-09
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    62   2e-09
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    62   2e-09
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    62   2e-09
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           62   2e-09
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        62   2e-09
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        62   2e-09
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    62   3e-09

>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
           sapiens]
          Length = 800

 Score = 1651 bits (4276), Expect = 0.0
 Identities = 800/800 (100%), Positives = 800/800 (100%)

Query: 1   MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA 60
           MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA
Sbjct: 1   MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA 60

Query: 61  STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGGRDVQEGAELPAV 120
           STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGGRDVQEGAELPAV
Sbjct: 61  STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGGRDVQEGAELPAV 120

Query: 121 LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN 180
           LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN
Sbjct: 121 LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN 180

Query: 181 GQETECQDDCFLGKSDLQNFEELREPAGTGPPFVLTQSSRPTDMLLNSLATSLSSRRMPS 240
           GQETECQDDCFLGKSDLQNFEELREPAGTGPPFVLTQSSRPTDMLLNSLATSLSSRRMPS
Sbjct: 181 GQETECQDDCFLGKSDLQNFEELREPAGTGPPFVLTQSSRPTDMLLNSLATSLSSRRMPS 240

Query: 241 SCPMTIFMRCRIRSRSPPLLGSSLGCPRSGAPRMFIVYHVAAGLPILPPAGHTLRLPPRS 300
           SCPMTIFMRCRIRSRSPPLLGSSLGCPRSGAPRMFIVYHVAAGLPILPPAGHTLRLPPRS
Sbjct: 241 SCPMTIFMRCRIRSRSPPLLGSSLGCPRSGAPRMFIVYHVAAGLPILPPAGHTLRLPPRS 300

Query: 301 PPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQG 360
           PPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQG
Sbjct: 301 PPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQG 360

Query: 361 LPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPS 420
           LPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPS
Sbjct: 361 LPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPS 420

Query: 421 PKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSEL 480
           PKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSEL
Sbjct: 421 PKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSEL 480

Query: 481 APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPR 540
           APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPR
Sbjct: 481 APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPR 540

Query: 541 GGAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSEDVCVVT 600
           GGAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSEDVCVVT
Sbjct: 541 GGAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSEDVCVVT 600

Query: 601 EYLWEGNSDPKVGSSDPVIPGTKADKKTKMGPMSEEDKRERRSLGVNPRDCSSLDDSSPS 660
           EYLWEGNSDPKVGSSDPVIPGTKADKKTKMGPMSEEDKRERRSLGVNPRDCSSLDDSSPS
Sbjct: 601 EYLWEGNSDPKVGSSDPVIPGTKADKKTKMGPMSEEDKRERRSLGVNPRDCSSLDDSSPS 660

Query: 661 GSAVLYPGLAASWSPQQSGTGSQNCLHPIGLSCCLPGLLAGLISPCSSDPTKLGYCVIAT 720
           GSAVLYPGLAASWSPQQSGTGSQNCLHPIGLSCCLPGLLAGLISPCSSDPTKLGYCVIAT
Sbjct: 661 GSAVLYPGLAASWSPQQSGTGSQNCLHPIGLSCCLPGLLAGLISPCSSDPTKLGYCVIAT 720

Query: 721 YQGEKQRLSTASGPQGRVFPPQKLLPLEMQERKPTPYPPRKRSVDHTGSSQQEGGTVEEV 780
           YQGEKQRLSTASGPQGRVFPPQKLLPLEMQERKPTPYPPRKRSVDHTGSSQQEGGTVEEV
Sbjct: 721 YQGEKQRLSTASGPQGRVFPPQKLLPLEMQERKPTPYPPRKRSVDHTGSSQQEGGTVEEV 780

Query: 781 ATFSVALKGQEEESSNTLQK 800
           ATFSVALKGQEEESSNTLQK
Sbjct: 781 ATFSVALKGQEEESSNTLQK 800


>gi|239756297 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 525

 Score =  536 bits (1381), Expect = e-152
 Identities = 285/355 (80%), Positives = 290/355 (81%), Gaps = 36/355 (10%)

Query: 1   MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA 60
           MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA
Sbjct: 1   MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA 60

Query: 61  STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGGRDVQEGAELPAV 120
           STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGG DVQEGAELPAV
Sbjct: 61  STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGGGDVQEGAELPAV 120

Query: 121 LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN 180
           LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN
Sbjct: 121 LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN 180

Query: 181 GQETECQDDCFLGKSDLQNFEELREPAGTGP----------------------------- 211
           GQETECQDDCFLGKSDLQNFEELREPAGTGP                             
Sbjct: 181 GQETECQDDCFLGKSDLQNFEELREPAGTGPTLPGGRESSEAYPLPQLGAIGSGQAVAYG 240

Query: 212 PFVLTQSSRPTDMLLNSLATSLSSRRMPSSCPMTIFMRCRIRSRSPPLLGSSLGCPRSGA 271
           PFVLTQSSRPTDMLLNSLATSLSSRRMPSSCPMTIFMRCRIRSRSPPLLGSSLGCPR+  
Sbjct: 241 PFVLTQSSRPTDMLLNSLATSLSSRRMPSSCPMTIFMRCRIRSRSPPLLGSSLGCPRTPT 300

Query: 272 PRMFIVYHVAAGLPILPPAGHTLRLPPRSPP-RLGRAPHFNGPPAHPGP--GRPS 323
           P   +      GLP     G + +     P   LGRA   +G P  PGP  G PS
Sbjct: 301 PG--LTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRA-SLSG-PFGPGPQGGPPS 351



 Score =  282 bits (721), Expect = 1e-75
 Identities = 140/155 (90%), Positives = 142/155 (91%), Gaps = 7/155 (4%)

Query: 387 RERAWPPPSL-------RTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSG 439
           R R+  PP L       RTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSG
Sbjct: 280 RIRSRSPPLLGSSLGCPRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSG 339

Query: 440 PFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPG 499
           PFGPGPQGGPPSRDRRHLGVQIGRVR PLGSALPYPARSELAPPGA+DALSPDPERPCPG
Sbjct: 340 PFGPGPQGGPPSRDRRHLGVQIGRVRAPLGSALPYPARSELAPPGAQDALSPDPERPCPG 399

Query: 500 TRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVR 534
           TRGVRSGREGLLSPAPRSALGETAPTAQFTFRK R
Sbjct: 400 TRGVRSGREGLLSPAPRSALGETAPTAQFTFRKRR 434


>gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo
           sapiens]
          Length = 488

 Score =  449 bits (1155), Expect = e-126
 Identities = 279/469 (59%), Positives = 300/469 (63%), Gaps = 70/469 (14%)

Query: 1   MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA 60
           MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA
Sbjct: 1   MGLCMGRLRGQAHFFLLHLLLTVPLLIVTAQSMVEHFVTEPHPLPCPWGPLGQLALHRGA 60

Query: 61  STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGGRDVQEGAELPAV 120
           STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGGRDVQEGAELPAV
Sbjct: 61  STKGLLTGGVWGLHSWPIGDGRATIHEAVVRASPWPSRLGTIHGVRGGRDVQEGAELPAV 120

Query: 121 LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN 180
           LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN
Sbjct: 121 LLTVAVVQSSGSSSKSKSEDDAFLPQRNLRETPISQKPLLNPSSTQGLTKPLADGTAQWN 180

Query: 181 GQETECQDDCFLGKSDLQNFEELREPAGTGPPFVLTQSSRPTDMLLNSLATSLSSRRMPS 240
           GQETECQDDCFLGKSDLQNFEELREPAGTGP            +L + L  +  + ++P 
Sbjct: 181 GQETECQDDCFLGKSDLQNFEELREPAGTGP------------LLGHLLELAKDALKLPD 228

Query: 241 SCPMTIFMRCRIRSRSPPL-LGSSLGCPRSGAPRMFIVYHVAAGLPILPPAGHTLRLPPR 299
                      + + S PL L ++ G              V  GLP +  A +  RLPP 
Sbjct: 229 D---------HLHALSNPLPLTTTAG--------------VVTGLPEVRGAPNVHRLPP- 264

Query: 300 SPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPR---GRQSLAEGVKRD 356
            PP L R P   G     G G PS       P       E G P+   GR SL+ G    
Sbjct: 265 -PPSL-RTP-TPGLTEGGGTGLPSKQRRGPSPK-----TELGGPQGSLGRASLS-GPFGP 315

Query: 357 GGQGLPDVEGAPDMGSSGEGAGLEEGS----PLRRERAWP------PPSLRTPTPGL--T 404
           G QG P       +G       +  GS    P R E A P       P    P PG    
Sbjct: 316 GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGV 375

Query: 405 EGGGTGLPSKQRRGPSPKTELG--GPQGSLGRASLSGPFGPGPQGGPPS 451
             G  GL S     P+P++ LG   P        +  P  PGP+GG  S
Sbjct: 376 RSGREGLLS-----PAPRSALGETAPTAQFTFRKVRNP--PGPRGGAMS 417



 Score =  429 bits (1104), Expect = e-120
 Identities = 211/235 (89%), Positives = 214/235 (91%), Gaps = 17/235 (7%)

Query: 360 GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGP 419
           GLP+V GAP++                  R  PPPSLRTPTPGLTEGGGTGLPSKQRRGP
Sbjct: 249 GLPEVRGAPNV-----------------HRLPPPPSLRTPTPGLTEGGGTGLPSKQRRGP 291

Query: 420 SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
           SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE
Sbjct: 292 SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 351

Query: 480 LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
           LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP
Sbjct: 352 LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 411

Query: 540 RGGAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSE 594
           RGGAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSE
Sbjct: 412 RGGAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSE 466


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 91/305 (29%), Positives = 107/305 (35%), Gaps = 30/305 (9%)

Query: 283  GLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESG 341
            G P LP  G T    P+ PP    A    G P   G PG P  +  P  P    L    G
Sbjct: 1272 GDPGLP--GRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPG 1329

Query: 342  TPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWP--PPSLRTP 399
             P  R    E   R G +G P   GAP     GEG GL    P R+    P  PP  R P
Sbjct: 1330 LPGPRGDPGERGPR-GPKGEP---GAPGQVIGGEGPGL----PGRKGDPGPSGPPGPRGP 1381

Query: 400  TPGLTEGGGTGLPSKQRRGPSPKTELGGPQG------SLGRASLSG-PFGPGPQG--GPP 450
                   G  GLP    +G        GP G      + G   L G P  PGPQG  GPP
Sbjct: 1382 LGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPP 1441

Query: 451  SRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGL 510
             +       + G   +P     P     E  P G   A+ P  +R  PG  G    +   
Sbjct: 1442 GKKGEKGDSEDGAPGLPGQPGSP----GEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGER 1497

Query: 511  LSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRPGWDT 570
              P P  + G      +   +    PPGP G      G +  PG        GP      
Sbjct: 1498 GPPGPAGSRGLPGVAGRPGAKGPEGPPGPTG----RQGEKGEPGRPGDPAVVGPAVAGPK 1553

Query: 571  PEKGD 575
             EKGD
Sbjct: 1554 GEKGD 1558



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 94/294 (31%), Positives = 109/294 (37%), Gaps = 55/294 (18%)

Query: 323  STSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGE-GAGLEE 381
            +T P P P  + C   + G P G   L   V   G  GLP   GAP  G  G  G+   +
Sbjct: 1239 TTQPRPEPCPVYCPKGQKGEP-GEMGLRGQVGPPGDPGLPGRTGAP--GPQGPPGSATAK 1295

Query: 382  GSPLRRERAWPPPSLRTPTPGLTEGGGT----------GLPSKQ----RRGP-SPKTELG 426
            G     ER +P    R  +PG     GT          GLP  +     RGP  PK E G
Sbjct: 1296 G-----ERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPG 1350

Query: 427  GP--------QGSLGRASLSGPFGP----GPQGGPPSRDRRHL-GVQIGRVRVPLGS-AL 472
             P         G  GR    GP GP    GP G P  R    L G  +   +   G    
Sbjct: 1351 APGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGP 1410

Query: 473  PYPARSELAP-----PGARDALSPDPERPC--PGTRGVR----SGREGLL-SPAPRSALG 520
            P P    +AP     PG     SP P+ P   PG +G +     G  GL   P      G
Sbjct: 1411 PGPGEGGIAPGEPGLPGLPG--SPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQG 1468

Query: 521  ETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRG--PRPGWDTPE 572
               P      +  R  PGP G A    G R PPGPA S    G   RPG   PE
Sbjct: 1469 PRGPPGAIGPKGDRGFPGPLGEA-GEKGERGPPGPAGSRGLPGVAGRPGAKGPE 1521



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 119/437 (27%), Positives = 151/437 (34%), Gaps = 85/437 (19%)

Query: 288  PPAGHTLRLP--PRSPPRLGRAPHFNGPPAH-----------PGPGRPSTSPCPL-PPSL 333
            PP    L  P  P+ P  L   P   GPP             PGP  PS    P   P L
Sbjct: 2187 PPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGL 2246

Query: 334  LCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDM----GSSGEGAGLEEGSPLRRER 389
                 E+G P G         +DG +G P V G+P +    G  GE      G+P +   
Sbjct: 2247 PGQVGETGKP-GAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPG--PTGAPGQAVV 2303

Query: 390  AWPPPSLRTPTPGLTEGGGTGLP-SKQRRG-PSPKTELGGPQGSLGRASLSG-PFGPGPQ 446
              P        PG   G   G P +K  RG P P+    G +G  GRA   G P   G +
Sbjct: 2304 GLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPR----GEKGEAGRAGEPGDPGEDGQK 2359

Query: 447  GGP-PSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDA---------LSPDPERP 496
            G P P   +   GV +     P G   P   + +L  PG   A           P  E  
Sbjct: 2360 GAPGPKGFKGDPGVGVPGSPGPPG---PPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMG 2416

Query: 497  CPGTRGVRS-----GREGLLSP-APRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTR 550
             PG  G R      GREG+  P  P    G   P      +  +  PG   G     G R
Sbjct: 2417 QPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV--GLPGPRGER 2474

Query: 551  SPPGPAESARSRGPRPGWDTP-----------EKGDHLLSFTMQEDVGPLSFSSEDVCVV 599
              PG     R    RPG + P           E+G+       + DVG      +     
Sbjct: 2475 GEPG----IRGEDGRPGQEGPRGLTGPPGSRGERGE-------KGDVGSAGLKGD----- 2518

Query: 600  TEYLWEGNSDPKVGSSDPVIPGTKADKKTKMGPMSEEDKRERRSLGVNPRDCSSLDDSSP 659
                 +G+S   +G   P   G K D   + GP   +  +  R    +P D  S  +   
Sbjct: 2519 -----KGDSAVILGPPGP--RGAKGDMGER-GPRGLDGDKGPRGDNGDPGDKGSKGEPGD 2570

Query: 660  SGSAVLYPGLAASWSPQ 676
             GSA L PGL     PQ
Sbjct: 2571 KGSAGL-PGLRGLLGPQ 2586



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 105/361 (29%), Positives = 127/361 (35%), Gaps = 72/361 (19%)

Query: 280  VAAGLPILP--PAGHTLRLPPRSPPRLG-RAPHFNGPPAHPG-PGRPSTSPCPLPPSLLC 335
            +A G P LP  P     + P   P + G +    +G P  PG PG P       PP  + 
Sbjct: 1418 IAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIG 1477

Query: 336  LWVESGTPRGRQSLAEGVKRD-----GGQGLPDVEGAPDM-GSSGE----GAGLEEGSPL 385
               + G P       E  +R      G +GLP V G P   G  G     G   E+G P 
Sbjct: 1478 PKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPG 1537

Query: 386  RR-ERAWPPPSLRTPT-------PGLTEG-----GGTGLPSKQRRG-PSPKTELG--GPQ 429
            R  + A   P++  P        P    G     G  G P     G P PK + G  GP 
Sbjct: 1538 RPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPI 1597

Query: 430  GSLGRASLSGPFG----------PGPQG--GPPSRDRRHLGVQIGRVRVPLGSALPYPA- 476
            G  GRA   G  G          PGP G  GP  RD   +G + G    P    LP  A 
Sbjct: 1598 GLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRD-GEVG-EKGDEGPPGDPGLPGKAG 1655

Query: 477  -RSELAPPGARDAL---------SPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTA 526
             R     PG R  +           D     PG+ G +  R     P P   L +T P A
Sbjct: 1656 ERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGA 1715

Query: 527  QFT----FRKVRNPPGPRG--------GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKG 574
            +       R    P GP+G        G     G R PPGP      RGP       EKG
Sbjct: 1716 REKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGP-----AGEKG 1770

Query: 575  D 575
            D
Sbjct: 1771 D 1771



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 85/306 (27%), Positives = 103/306 (33%), Gaps = 58/306 (18%)

Query: 301  PPRLGRAPHFNGPPAHPGPGRPSTSPCPL------PPSLLCLWVESGT-----PRGRQSL 349
            PP L   P   GPP  PGP      P P       PP L     E G+     P+G + +
Sbjct: 2077 PPGLPGTP---GPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGV 2133

Query: 350  AEGVK----------RDGGQGLPDV------EGAPDM----GSSGEGAGLEEGSPLRRER 389
              G+K          +DG  GLP        EG P +    G  G   G  +  P     
Sbjct: 2134 P-GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPG 2192

Query: 390  AWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG-PGPQG- 447
               P   + P+    E G TG P +   GP+    L GP G  G     G  G PG  G 
Sbjct: 2193 LAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGE 2252

Query: 448  ----GPPSRD-RRHLGVQIGRVRVPLGSALPYPA--RSELAPPGARDALSPDPERPCPGT 500
                G P RD         G   VP    LP P   + E  P GA       P +   G 
Sbjct: 2253 TGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGA-------PGQAVVGL 2305

Query: 501  RGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESAR 560
             G + G +G         +GE            R  PGPRG    A     P  P E  +
Sbjct: 2306 PGAK-GEKGAPGGLAGDLVGEPGAKGD------RGLPGPRGEKGEAGRAGEPGDPGEDGQ 2358

Query: 561  SRGPRP 566
               P P
Sbjct: 2359 KGAPGP 2364



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 85/303 (28%), Positives = 104/303 (34%), Gaps = 68/303 (22%)

Query: 299  RSPPRLGRAPHFNGPPAHPGPGRPSTSPC----PLPPSLLCLWVESGTP--RGRQSLAEG 352
            R PP L      +G P   GP  P+ +      P    L  L  E G P   G   L   
Sbjct: 1772 RGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGK 1831

Query: 353  VKRDGGQGLPDVEGAP-DMGSSGE--------GAGLEEGSPLRRERAWP-------PPSL 396
               DG  GL    G P D G  G          +G E     + ER  P       PP L
Sbjct: 1832 PGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGL 1891

Query: 397  RTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG-PGPQGGPPSRDR- 454
              P  G    G  G+P     G  PK + G   GS G   L G  G  G  G  P+ DR 
Sbjct: 1892 PGPV-GPPGQGFPGVPG----GTGPKGDRG-ETGSKGEQGLPGERGLRGEPGSVPNVDRL 1945

Query: 455  -RHLGVQIGRVRVPL-------GSALPYPARSELAPPGARDALSPDPERPC--PGTRGVR 504
                G++   +R  +       GS LP P R       + +   P  E P   PG RG++
Sbjct: 1946 LETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLK 2005

Query: 505  SGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGP 564
              R                             PGP+G    A G R PPGP+  A   G 
Sbjct: 2006 GDR---------------------------GDPGPQGPPGLALGERGPPGPSGLAGEPG- 2037

Query: 565  RPG 567
            +PG
Sbjct: 2038 KPG 2040



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 82/289 (28%), Positives = 100/289 (34%), Gaps = 54/289 (18%)

Query: 307  APHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEG 366
            AP   G    PG G P +   P PP                    GVK  G  GLP + G
Sbjct: 2361 APGPKGFKGDPGVGVPGSPGPPGPP--------------------GVK--GDLGLPGLPG 2398

Query: 367  APDM----GSSGEGAGLEEGSPL-RRERAWPPPSLRTPTPGLTEG--GGTGLPS----KQ 415
            AP +    G +G    + +  P   R  A PP     P P    G  G  G P     K 
Sbjct: 2399 APGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKG 2458

Query: 416  RRGPSPKTELGGPQGSLGRASLSGPFG-PGPQG-----GPP-SRDRRHLGVQIGRVRVPL 468
             +G  P   L GP+G  G   + G  G PG +G     GPP SR  R     +G   +  
Sbjct: 2459 DKG-DPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKG 2517

Query: 469  GSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQF 528
                   +   L PPG R A     ER   G  G +  R     P  + + GE       
Sbjct: 2518 DKG---DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSA 2574

Query: 529  TFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGD 575
                +R   GP+G  GA    G    PG       RG        EKGD
Sbjct: 2575 GLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRG--------EKGD 2615



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 94/380 (24%), Positives = 132/380 (34%), Gaps = 55/380 (14%)

Query: 356  DGGQGLPDVEGAP-DMGSSGE-----GAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGT 409
            DG +G     G P D GS GE      AGL     L   +  P  +     PG    G  
Sbjct: 2547 DGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPG--SPGKD 2604

Query: 410  GLPS----KQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRD--RRHLGVQIGR 463
            G+P     K   G      L G +G  G   L G  G   + GPP R     H G ++G 
Sbjct: 2605 GVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKG-EMGE 2663

Query: 464  VRVPLGSALPYPA--------RSELAPPGARDALSPDPERPCPGTRGV--RSGREGLLS- 512
              VP  S  P           R     PG +       ER  PG  G    SG +G    
Sbjct: 2664 PGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP 2723

Query: 513  PAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRPGWDTPE 572
            P P  ++G   P      +  R PPG R   + A G   P  P E      P P     E
Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGERGPPGER--VVGAPGV--PGAPGERGEQGRPGPAGPRGE 2779

Query: 573  KG------DHLLSFTMQEDVGPLSFSSEDVCVVTEYLWEGNSDPKVGSSD---------P 617
            KG      D +  F  QE        S+      +++  G+      ++D         P
Sbjct: 2780 KGEAALTEDDIRGFVRQE-------MSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVP 2832

Query: 618  VIPGTKADKKTKMGPMSEEDKRERRSLGVNPRDCSSLDDSSPSGSAVLYPGLAASWSPQ- 676
            V+  + A+++ ++ P  +E            +D  +  DS    S  L  G   +++ + 
Sbjct: 2833 VLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRW 2892

Query: 677  --QSGTGSQNCLHPIGLSCC 694
              ++ TGS    HP     C
Sbjct: 2893 YHRAVTGSTEACHPFVYGGC 2912



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 68/249 (27%), Positives = 85/249 (34%), Gaps = 62/249 (24%)

Query: 352  GVKRDGG-QGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTG 410
            G K D G QG P  EG   +G  GE         L+ +R  P P      PGL  G    
Sbjct: 1979 GPKGDSGEQGPPGKEGP--IGFPGERG-------LKGDRGDPGPQ---GPPGLALG---- 2022

Query: 411  LPSKQRRGPSPKTELGGPQGSLGRASLSGPFG-------PGPQGGPPSRDRRHLGVQIGR 463
                  RGP   + L G  G  G   L G  G       PG +G    +  R    + G 
Sbjct: 2023 -----ERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077

Query: 464  VRVPLGSALPYP-------------ARSELAPPGARDA---------LSPDPERPCPGTR 501
              +P     P P                E  PPG + A           P  +R  PG +
Sbjct: 2078 PGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIK 2137

Query: 502  GVRS-----GREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPA 556
            G R      G++G  +P      G   P  +   +  R PPGP GG     G   PPG  
Sbjct: 2138 GDRGEPGPRGQDG--NPGLPGERGMAGPEGKPGLQGPRGPPGPVGG----HGDPGPPGAP 2191

Query: 557  ESARSRGPR 565
              A   GP+
Sbjct: 2192 GLAGPAGPQ 2200



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 70/249 (28%), Positives = 89/249 (35%), Gaps = 47/249 (18%)

Query: 311  NGPPAHPGPGRPSTSPCPL-PPSLLCLWVESGTPRGRQSLAEGVKRDGG----QGLPDVE 365
            NG P   GP      P P  PP  L   V++G P  R+    G +   G    +G P + 
Sbjct: 1684 NGSPGSSGPKGDRGEPGPPGPPGRL---VDTG-PGAREKGEPGDRGQEGPRGPKGDPGLP 1739

Query: 366  GAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTEL 425
            GAP  G  G          +   R  P P      PG+    G     K  RGP      
Sbjct: 1740 GAP--GERG----------IEGFRGPPGPQ---GDPGVRGPAG----EKGDRGPPGLDGR 1780

Query: 426  GGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGA 485
             G  G  G A  SGP G   + G P RD        G   +     LP P+     PPG 
Sbjct: 1781 SGLDGKPGAAGPSGPNGAAGKAGDPGRD--------GLPGLRGEQGLPGPS----GPPGL 1828

Query: 486  RDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMS 545
                  D +   PG  G ++G  G   P      GE   +   + R+ R+ P    GA  
Sbjct: 1829 PGKPGEDGK---PGLNG-KNGEPG--DPGEDGRKGEKGDSGA-SGREGRDGPKGERGAPG 1881

Query: 546  AAGTRSPPG 554
              G + PPG
Sbjct: 1882 ILGPQGPPG 1890



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 67/233 (28%), Positives = 80/233 (34%), Gaps = 60/233 (25%)

Query: 339  ESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSG----EGAGLEEGSPLRRERAWPPP 394
            E+G P GR  LA      G  G+P   GAP  G  G    +G    +G P          
Sbjct: 2645 EAGPP-GRPGLAGHKGEMGEPGVPGQSGAP--GKEGLIGPKGDRGFDGQP---------- 2691

Query: 395  SLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDR 454
                P     E G  G P            +GG  G  G    +GP  PGP G    R  
Sbjct: 2692 ---GPKGDQGEKGERGTPG-----------IGGFPGPSGNDGSAGP--PGPPGSVGPRGP 2735

Query: 455  RHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPA 514
              L  Q G                E  PPG R   +P      PG  G R G +G   PA
Sbjct: 2736 EGLQGQKG----------------ERGPPGERVVGAPG----VPGAPGER-GEQGRPGPA 2774

Query: 515  -PRSALGETAPTAQFTFRKVRNPPGPR---GGAMSAAGTRSPPGPAESARSRG 563
             PR   GE A T       VR          G   A+G+R  P P+ +A + G
Sbjct: 2775 GPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSR--PLPSYAADTAG 2825


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 88/309 (28%), Positives = 112/309 (36%), Gaps = 44/309 (14%)

Query: 285 PILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPC-----PLPPSLLCLWV 338
           P+ P     L  PP +P   G    F GPP  PG PG  ++ P      P PP       
Sbjct: 180 PMGPSGPRGLPGPPGAPGPQG----FQGPPGEPGEPG--ASGPMGPRGPPGPPGKNGDDG 233

Query: 339 ESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRT 398
           E+G P GR          G +GLP   G P M      +GL+ G+      A P     +
Sbjct: 234 EAGKP-GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD-GAKGDAGPAGPKGEPGS 291

Query: 399 PTPGLTEG--GGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRH 456
           P      G  G  GLP ++ R  +P     G +G+ G    +GP GP    GPP      
Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGP--AGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349

Query: 457 LGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVR--SGREGLL-SP 513
                   + P GS  P   R E  PPG   A  P       G  G +  +G  G+  +P
Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAP 409

Query: 514 APRSALGETAPTAQFTFRKVRNPPGPRG-----------------GAMSAAGTRSPPGPA 556
               A G + P           PPGP+G                 G     G + PPGPA
Sbjct: 410 GFPGARGPSGPQGP------GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463

Query: 557 ESARSRGPR 565
                RG R
Sbjct: 464 GEEGKRGAR 472



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 86/265 (32%), Positives = 100/265 (37%), Gaps = 38/265 (14%)

Query: 302 PRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGL 361
           P +  AP F G     GP  P   P P   S      E G P  +     G K  G  G 
Sbjct: 403 PGIAGAPGFPGARGPSGPQGPGGPPGPKGNS-----GEPGAPGSKGDT--GAK--GEPGP 453

Query: 362 PDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSP 421
             V+G P       G   EEG   R  R  P P+     PG  E GG G      RG   
Sbjct: 454 VGVQGPP-------GPAGEEGK--RGARGEPGPTGLPGPPG--ERGGPG-----SRGFPG 497

Query: 422 KTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELA 481
              + GP+G  G     GP   GP+G P    R       G   +      P P   +  
Sbjct: 498 ADGVAGPKGPAGERGSPGP--AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP-DGKTG 554

Query: 482 PPG-ARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPR 540
           PPG A     P P  P PG RG ++G  G   P P+ A GE     +   R V  PPG  
Sbjct: 555 PPGPAGQDGRPGPPGP-PGARG-QAGVMGF--PGPKGAAGEPGKAGE---RGVPGPPGAV 607

Query: 541 G--GAMSAAGTRSPPGPAESARSRG 563
           G  G    AG + PPGPA  A  RG
Sbjct: 608 GPAGKDGEAGAQGPPGPAGPAGERG 632



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 100/327 (30%), Positives = 112/327 (34%), Gaps = 71/327 (21%)

Query: 282  AGLPILP-PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVES 340
            AG P  P PAG      PR        P   GPP  PGP     SP    P+        
Sbjct: 892  AGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPA-----GAP 946

Query: 341  GTPRGRQSLA--EGVKRDGGQ-------GLPDVEGAPDMGSSG-EGAGLEEGSPLRRERA 390
            GTP G Q +A   GV    GQ       GLP   G P  G  G  GA  E G P      
Sbjct: 947  GTP-GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP--GKQGPSGASGERGPP----GP 999

Query: 391  WPPPSLRTPTPGLTEGGGTGLPSKQ----------RRGPSPKTELGGPQGSLGRASLSGP 440
              PP L  P PG  E G  G P  +           +G   +T   GP G+ G     GP
Sbjct: 1000 MGPPGLAGP-PG--ESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP 1056

Query: 441  FGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGT 500
             GP  + G    DR   G        P G   P  AR    P G R       E+   G 
Sbjct: 1057 VGPAGKSG----DRGETGPA-----GPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107

Query: 501  RGVR--SGREGLLSPAPRSALGETAPTAQFTFRKVRNPPG-------------------- 538
            +G R  SG +G   P P  + GE  P+        R PPG                    
Sbjct: 1108 KGHRGFSGLQG--PPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPP 1165

Query: 539  -PRGGAMSAAGTRSPPGPAESARSRGP 564
             PRG     AG   PPGP       GP
Sbjct: 1166 GPRG-RTGDAGPVGPPGPPGPPGPPGP 1191



 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 97/310 (31%), Positives = 116/310 (37%), Gaps = 40/310 (12%)

Query: 298 PRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRD 356
           P+ P     +P   GP   PG  GRP  +  P    L       G P G+        +D
Sbjct: 504 PKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG-PDGKTGPPGPAGQD 562

Query: 357 GGQGLPDVEGAPD----MGSSG-EGAGLEEGSPLRRERAWP-PPSLRTPTPGLTEGGGTG 410
           G  G P   GA      MG  G +GA  E G     ER  P PP    P     E G  G
Sbjct: 563 GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA--GERGVPGPPGAVGPAGKDGEAGAQG 620

Query: 411 LPSKQRRGPSPKTELGGPQGSLGRASLSGPFG-------PGPQGGP-------PSRDRRH 456
            P     GP+ +    GP GS G   L GP G       PG QG P       PS  R  
Sbjct: 621 PPGPA--GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678

Query: 457 LGVQIGR-VRVPLGSALPYPARSELAPPGAR-DALSPDP--ERPCPGTRGVRSGREGLLS 512
            G    R V+ P G A P  A       GA+ DA +P     +  PG +G+   R     
Sbjct: 679 RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738

Query: 513 PAPRSALGETAP------TAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGP 564
           P P+   G+  P        +   R +  P GP G  GA    G   P GPA    +RG 
Sbjct: 739 PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARG- 797

Query: 565 RPGWDTPEKG 574
            PG D  E G
Sbjct: 798 APG-DRGEPG 806



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 95/335 (28%), Positives = 108/335 (32%), Gaps = 59/335 (17%)

Query: 283 GLPILP--PAGHTLRLPPRSPPRLGRAPHFN--GPPAHPG----------PGRPSTSPCP 328
           GLP  P  P     + PP  P   G +      GPP  PG          PGRP     P
Sbjct: 188 GLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPP 247

Query: 329 LPPSLLCLWVESGTP-----RGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGS 383
            P     L   +G P     RG   L +G K D G   P  +G P  GS GE     +  
Sbjct: 248 GPQGARGLPGTAGLPGMKGHRGFSGL-DGAKGDAGPAGP--KGEP--GSPGENGAPGQMG 302

Query: 384 P--LRRERAWP----PPSLR--------TPTPGLT-EGGGTGLP----SKQRRGPSPKTE 424
           P  L  ER  P    P   R           PG T   G  G P    +K   GP     
Sbjct: 303 PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG 362

Query: 425 LGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYP-ARSELAPP 483
             GPQG  G     GP G     G P  D +  G +       +  A  +P AR    P 
Sbjct: 363 SEGPQGVRGEPGPPGPAGAAGPAGNPGADGQP-GAKGANGAPGIAGAPGFPGARGPSGPQ 421

Query: 484 GARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-- 541
           G      P      PG  G +        P P    G   P  +   R  R  PGP G  
Sbjct: 422 GPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLP 481

Query: 542 ------------GAMSAAGTRSPPGPAESARSRGP 564
                       G   A G   P GPA    S GP
Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGP 516



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 89/288 (30%), Positives = 102/288 (35%), Gaps = 56/288 (19%)

Query: 298 PRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRD 356
           PR P      P  +G P  PG PG P     P PP L       G    + S     K  
Sbjct: 119 PRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGL------GGNFAPQLSYGYDEKST 172

Query: 357 GGQGLPDVEGAPDMGSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQ 415
           GG  +P       MG SG  G     G+P  +    PP       PG  E G +G P   
Sbjct: 173 GGISVPG-----PMGPSGPRGLPGPPGAPGPQGFQGPPGE-----PG--EPGASG-PMGP 219

Query: 416 RRGPSPKTELG--GPQGSLGRASLSGPFGPGPQG--------GPPSRDRRHLGVQIGRVR 465
           R  P P  + G  G  G  GR    GP  PGPQG        G P   + H G     + 
Sbjct: 220 RGPPGPPGKNGDDGEAGKPGRPGERGP--PGPQGARGLPGTAGLPGM-KGHRG--FSGLD 274

Query: 466 VPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPT 525
              G A P   + E   PG   A      R  PG RG R G     +P P  A G    T
Sbjct: 275 GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERG-RPG-----APGPAGARGNDGAT 328

Query: 526 AQFTFRKVRNPPGPRG--------GAMSAAGTRSPPGPAESARSRGPR 565
                     PPGP G        GA+ A G   P GP  S   +G R
Sbjct: 329 G------AAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR 370



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 88/295 (29%), Positives = 103/295 (34%), Gaps = 59/295 (20%)

Query: 298 PRSPPRLGRAPHFNGPPAH---PGP-------GRPSTSPCPLPPSLLCLWVESGTPRGRQ 347
           P  PP     P   G P     PGP       G P       PP           PRG  
Sbjct: 648 PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPG-------PAGPRGAN 700

Query: 348 SLA--EGVKRDGGQ-GLPDVEGAPDM-GSSGE--GAGLE-------EGSPLRRERAWPPP 394
                +G K D G  G P  +GAP + G  GE   AGL        +  P   + +    
Sbjct: 701 GAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760

Query: 395 SLRTPTPGLTEGGGTGLPS-KQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRD 453
            +R  T  +   G  G P  K   GPS      G +G+ G     GP GP    GPP  D
Sbjct: 761 GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGAD 820

Query: 454 RRHLGVQIGRVRVPLGSALPYPARSELAPPG-ARDALSPDP--ERPCPGTRGVRSGREGL 510
                 Q G    P G A    A+ +  PPG A  A  P P      PG +G R      
Sbjct: 821 G-----QPGAKGEP-GDA---GAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG----- 866

Query: 511 LSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPR 565
            S  P  A G      +        PPGP G     AG   PPGPA     +GPR
Sbjct: 867 -SAGPPGATGFPGAAGRV------GPPGPSGN----AGPPGPPGPAGKEGGKGPR 910



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 87/292 (29%), Positives = 98/292 (33%), Gaps = 58/292 (19%)

Query: 301  PPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGT-PRGRQSLAEGVKRDGGQ 359
            PP     P   G    PGP   +  P P  P+      E G  PRG           G  
Sbjct: 870  PPGATGFPGAAGRVGPPGPSGNAGPPGPPGPA----GKEGGKGPRGET---------GPA 916

Query: 360  GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEG--GGTGLPSKQ-R 416
            G P   G P       G   E+GSP     A  P    TP P    G  G  GLP ++  
Sbjct: 917  GRPGEVGPP----GPPGPAGEKGSPGADGPAGAPG---TPGPQGIAGQRGVVGLPGQRGE 969

Query: 417  RG----PSPKTELG--GPQGSLGRASLSGPFGPGPQGGPPSRDRRH----LGVQIGRVRV 466
            RG    P P  E G  GP G+ G     GP GP    GPP    R          GR   
Sbjct: 970  RGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGS 1029

Query: 467  PLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTA 526
            P G+           PPGA  A    P  P P     +SG  G   PA     G   P  
Sbjct: 1030 P-GAKGDRGETGPAGPPGAPGA----PGAPGPVGPAGKSGDRGETGPA-----GPAGPVG 1079

Query: 527  QFTFRKVRNPPGPRG--------------GAMSAAGTRSPPGPAESARSRGP 564
                R    P GPRG              G    +G + PPGP  S   +GP
Sbjct: 1080 PVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGP 1131



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 60/242 (24%), Positives = 77/242 (31%), Gaps = 39/242 (16%)

Query: 283  GLPILP-PAGHTLRLPP------RSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLL 334
            G P LP P+G   +  P      R PP     P   GPP   G  G P     P      
Sbjct: 971  GFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP------ 1024

Query: 335  CLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPD-MGSSGEGAGLEEGSPLRRERAWPP 393
                  G+P  +    E     G  G P   GAP  +G +G+     E  P        P
Sbjct: 1025 ---GRDGSPGAKGDRGE-TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP 1080

Query: 394  PSLRTPTPGLTEGGGTGLPSKQR-------------RGPSPKTELGGPQGSLGRASLSGP 440
               R P       G  G   +Q              +GP       G QG  G +  +GP
Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGP 1140

Query: 441  FGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGT 500
             GP    G P +D       +  +  P+G   P     +  P G      P P  P P +
Sbjct: 1141 RGPPGSAGAPGKD------GLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGP-PGPPGPPS 1193

Query: 501  RG 502
             G
Sbjct: 1194 AG 1195



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 43/150 (28%), Positives = 49/150 (32%), Gaps = 24/150 (16%)

Query: 418 GPSPKTELGGPQGSLGRASLSG----PFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALP 473
           GP   T   GP+G  G     G    P  PGP G P       LG   G     L     
Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLG---GNFAPQLSYGYD 168

Query: 474 YPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKV 533
             +   ++ PG    + P   R  PG  G   G +G   P      GE            
Sbjct: 169 EKSTGGISVPG---PMGPSGPRGLPGPPGA-PGPQGFQGPP-----GEPGEPGASGPMGP 219

Query: 534 RNPPGPRG--------GAMSAAGTRSPPGP 555
           R PPGP G        G     G R PPGP
Sbjct: 220 RGPPGPPGKNGDDGEAGKPGRPGERGPPGP 249



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 45/145 (31%), Positives = 54/145 (37%), Gaps = 39/145 (26%)

Query: 423 TELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAP 482
           T + GP+G       +GP GP    GPP RD    G+  G+  +P     P P      P
Sbjct: 108 TGVEGPKGD------TGPRGPRGPAGPPGRD----GIP-GQPGLPGPPGPPGPP----GP 152

Query: 483 PGARDALSPDPER----------PCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRK 532
           PG     +P                PG  G  SG  GL  P P  A G          + 
Sbjct: 153 PGLGGNFAPQLSYGYDEKSTGGISVPGPMG-PSGPRGL--PGPPGAPGP---------QG 200

Query: 533 VRNPPGPRG--GAMSAAGTRSPPGP 555
            + PPG  G  GA    G R PPGP
Sbjct: 201 FQGPPGEPGEPGASGPMGPRGPPGP 225



 Score = 30.0 bits (66), Expect = 8.9
 Identities = 23/72 (31%), Positives = 26/72 (36%), Gaps = 9/72 (12%)

Query: 492 DPERPCPGTRGVRSGR------EGLLSPAPRSALGETAPTAQFTFRKVRNPPGP--RGGA 543
           D  + CPG   V  G       +G  SP  +   G   P      R  R P GP  R G 
Sbjct: 76  DETKNCPGAE-VPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGI 134

Query: 544 MSAAGTRSPPGP 555
               G   PPGP
Sbjct: 135 PGQPGLPGPPGP 146


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 93/339 (27%), Positives = 124/339 (36%), Gaps = 46/339 (13%)

Query: 257 PPLLGSSLGCPRSGAPRMFIVYHVAAGLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAH 316
           PP LG +     +G          A G  +    G    + PR PP    AP   G   +
Sbjct: 172 PPGLGGNFAAQMAGG-----FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 226

Query: 317 PG-PGRPSTSPC------PLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPD 369
           PG PG P  S        P PP       E+G P G+          G +G P   G P 
Sbjct: 227 PGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP-GKAGERGPPGPQGARGFPGTPGLPG 285

Query: 370 M-GSSG----EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTE 424
           + G  G    +GA  E G+P  +  +  P    +P P     G  GLP +  RG +    
Sbjct: 286 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM----GPRGLPGE--RGRTGPAG 339

Query: 425 LGGPQGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPP 483
             G +G+ G+   +GP GP GP GGP          + G    P G+  P  A+     P
Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG----PTGARGPEGAQGPRGEP 395

Query: 484 GARDALSPDPERPCPGTRGV-----RSGREGLLS----------PAPRSALGETAPTAQF 528
           G   +  P      PGT G+      +G  G+            P P+ A G   P  Q 
Sbjct: 396 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 455

Query: 529 TFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR 565
               +    G +G  G    AG +  PGPA     RG R
Sbjct: 456 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 87/306 (28%), Positives = 103/306 (33%), Gaps = 68/306 (22%)

Query: 301  PPRLGRAPHFNGPPAHPG----PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRD 356
            PP     P   GP   PG    PG    S    PP           P+G       V   
Sbjct: 937  PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG----------PQGLAGQRGIVGLP 986

Query: 357  GGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT----EGGGTGLP 412
            G +G     G P  G SGE    ++G+P       PP  +  P  GLT    E G  G P
Sbjct: 987  GQRGERGFPGLP--GPSGEPG--KQGAPGASGDRGPPGPVGPP--GLTGPAGEPGREGSP 1040

Query: 413  SKQRRGPSPKTELGGPQGSLGRASLSG-PFGPGPQGGP-------PSRDRRHLGVQIGRV 464
                 GP  +    G +G  G     G P  PGP G P          DR   G Q    
Sbjct: 1041 GAD--GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ---- 1094

Query: 465  RVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVR-----------------SGR 507
              P+G + P  AR    P G R       E   PG RG++                 SG 
Sbjct: 1095 -GPMGPSGPAGARGIQGPQGPRGDKGEAGE---PGERGLKGHRGFTGLQGLPGPPGPSGD 1150

Query: 508  EGLLSPA----PRSALGETAPTAQFTFRKVRNP---PGPRG--GAMSAAGTRSPPGPAES 558
            +G   PA    PR   G   P+ +     +  P   PGPRG  G    AG    PGP   
Sbjct: 1151 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP 1210

Query: 559  ARSRGP 564
                GP
Sbjct: 1211 PGPPGP 1216



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 86/309 (27%), Positives = 105/309 (33%), Gaps = 56/309 (18%)

Query: 298 PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTP--------RG 345
           PR PP         GPP  PG     G+P  +    PP         GTP        RG
Sbjct: 241 PRGPP---------GPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291

Query: 346 RQSLAEGVKRDGGQGLPDVEGAPDMGSSGE----GAGLEEGSPLRRERAWPP-------- 393
              L +G K  G  G P V+G  + GS GE    G     G P  R R  P         
Sbjct: 292 YPGL-DGAK--GEAGAPGVKG--ESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 346

Query: 394 ---PSLRTPTPGLTEGGGTGLPSKQ-RRGPSPKTELGGPQGSLG-RASLSGPFGPGPQGG 448
              P    P   +   GG G P     +G +  T   GP+G+ G R     P  PGP G 
Sbjct: 347 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 406

Query: 449 PPSRDRRHLGVQIGRVRVP-LGSALPYPA-RSELAPPGARDALSPDPERPCPGTRGVRSG 506
             +     +    G    P +  A  +P  R    P GA   L P  +   PG  G +  
Sbjct: 407 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE 466

Query: 507 REGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPP------GP 555
           +     P P    G   P  +   R  R  PG  G     G   A G R  P      GP
Sbjct: 467 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 526

Query: 556 AESARSRGP 564
             +   RGP
Sbjct: 527 KGAPGERGP 535



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 86/292 (29%), Positives = 101/292 (34%), Gaps = 63/292 (21%)

Query: 299 RSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDG 357
           R P  L      NG P  PG PG P        P           P+G+   +     DG
Sbjct: 533 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG-------DAGPQGKVGPSGAPGEDG 585

Query: 358 GQGLPDVEGAPD----MGSSG-EGAGLEEGSPLRRERAWP-PPSLRTPTPGLTEGGGTGL 411
             G P  +GA      MG  G +GA  E G     E+  P  P LR       E G  G 
Sbjct: 586 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKA--GEKGLPGAPGLRGLPGKDGETGAAGP 643

Query: 412 PSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSA 471
           P     GP+ +    G  G  G   L GP GP  +GG P           G   VP G A
Sbjct: 644 PGPA--GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP-----------GDQGVP-GEA 689

Query: 472 LPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSP----------APRSALGE 521
                       GA   + P  ER  PG RG   G +GL  P           P+ A G 
Sbjct: 690 ------------GAPGLVGPRGERGFPGERG-SPGAQGLQGPRGLPGTPGTDGPKGASGP 736

Query: 522 TAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR--PGWD 569
             P         + PPG +G  G   AAG   P G       +GP   PG D
Sbjct: 737 AGPPG------AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 782



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 80/266 (30%), Positives = 101/266 (37%), Gaps = 40/266 (15%)

Query: 302 PRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGL 361
           P +  AP F GP   PGP + +T P                P+G Q+   G+    G+  
Sbjct: 425 PGIAGAPGFPGPRGPPGP-QGATGPLG--------------PKG-QTGEPGIAGFKGEQG 468

Query: 362 PDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSP 421
           P  E  P       G   EEG   R  R  P        PG  E G  G      RG   
Sbjct: 469 PKGEPGPAGPQGAPGPAGEEGK--RGARGEPGGVGPIGPPG--ERGAPG-----NRGFPG 519

Query: 422 KTELGGPQGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSEL 480
           +  L GP+G+ G    SG  GP G  G P       L    G    P G A P   + ++
Sbjct: 520 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP-GDAGP---QGKV 575

Query: 481 APPGARDALSPDPERPCPGTRGVRSGREGLLS-PAPRSALGETAPTAQFTFRKVRNPPGP 539
            P GA      D     PG +G R G+ G++  P P+ A GE     +   + +   PG 
Sbjct: 576 GPSGAP---GEDGRPGPPGPQGAR-GQPGVMGFPGPKGANGEPGKAGE---KGLPGAPGL 628

Query: 540 RG--GAMSAAGTRSPPGPAESARSRG 563
           RG  G     G   PPGPA  A  RG
Sbjct: 629 RGLPGKDGETGAAGPPGPAGPAGERG 654



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 81/271 (29%), Positives = 95/271 (35%), Gaps = 62/271 (22%)

Query: 312 GPPAHPG----PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGA 367
           G P  PG    PG+   +    PP           P G +         G QGLP   G 
Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPG-------PAGPAGERGEQGAPGPSGFQGLPGPPGP 673

Query: 368 PDMGSSGEGAGL--EEGSP----LRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSP 421
           P  G      G+  E G+P     R ER +P         GL   G  GLP       +P
Sbjct: 674 PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ--GPRGLPG------TP 725

Query: 422 KTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQ-IGRVRVPLGSALPYPARSEL 480
            T+  GP+G+      SGP GP    GPP       G+Q +   R   G A P   R ++
Sbjct: 726 GTD--GPKGA------SGPAGPPGAQGPP-------GLQGMPGERGAAGIAGPKGDRGDV 770

Query: 481 APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPR 540
              G   A   D  R   G  G          P P  A GE              PPGP 
Sbjct: 771 GEKGPEGAPGKDGGRGLTGPIG---------PPGPAGANGEKGEVG---------PPGPA 812

Query: 541 G--GAMSAAGTRSPPGPAESARSRGPRPGWD 569
           G  GA  A G R   GP   A   GP PG D
Sbjct: 813 GSAGARGAPGERGETGPPGPAGFAGP-PGAD 842



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 85/297 (28%), Positives = 105/297 (35%), Gaps = 63/297 (21%)

Query: 299 RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRD 356
           + P  L   P  +GP    GP  P  +  P  P L       G P  RG   +A G K D
Sbjct: 716 QGPRGLPGTPGTDGPKGASGPAGPPGAQGP--PGL------QGMPGERGAAGIA-GPKGD 766

Query: 357 GGQ-GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQ 415
            G  G    EGAP  G  G G GL    P+       PP    P     E G  G P   
Sbjct: 767 RGDVGEKGPEGAP--GKDG-GRGLT--GPIG------PPG---PAGANGEKGEVGPP--- 809

Query: 416 RRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRD-------RRHLGVQIGRV---- 464
             GP+      G +G+ G    +GP GP    GPP  D        +    Q G      
Sbjct: 810 --GPAGSA---GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG 864

Query: 465 -RVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRG-----VRSGREGLLSP----- 513
            + P G+  P        P GAR A  P      PG  G       +G  G   P     
Sbjct: 865 PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG 924

Query: 514 --APRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESARSRG 563
              P+ A G++ P  +     ++ P GP G     G    +G   PPGP   A  RG
Sbjct: 925 KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 981



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 78/277 (28%), Positives = 93/277 (33%), Gaps = 69/277 (24%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
            G    PGP  PS +P P  P+ +        P+G +         G QG P   G P  G
Sbjct: 858  GDAGAPGPQGPSGAPGPQGPTGVT------GPKGAR---------GAQGPPGATGFP--G 900

Query: 372  SSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGS 431
            ++G              R  PP S   P P    G       K  RG S      GP G 
Sbjct: 901  AAG--------------RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS------GPPGR 940

Query: 432  LGRASLSGPFGP----------GPQG--GPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
             G   L GP GP          GP G  GPP    + L  Q G V +P         R E
Sbjct: 941  AGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG--PQGLAGQRGIVGLP-------GQRGE 991

Query: 480  LAPPGARDALSPDPERPCPGTRGVRS-----GREGLLSPA----PRSALGETAPTAQFTF 530
               PG         ++  PG  G R      G  GL  PA       + G   P  +   
Sbjct: 992  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051

Query: 531  RKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR 565
              V+   G  G  GA  A G    PGPA     +G R
Sbjct: 1052 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 75/282 (26%), Positives = 90/282 (31%), Gaps = 61/282 (21%)

Query: 312 GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
           G P +PGP  P     P PP L                       GG     + G  D  
Sbjct: 156 GTPGNPGP--PGPPGPPGPPGL-----------------------GGNFAAQMAGGFDEK 190

Query: 372 SSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGG-------GTGLPSKQRRGPSPKTE 424
           + G   G+ +G         PP     P P   +G        G   P   R  P P  +
Sbjct: 191 AGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK 250

Query: 425 LG--GPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP-----LGSALPYPAR 477
            G  G  G  G+A   GP  PGPQG         L    G    P      G A     +
Sbjct: 251 PGDDGEAGKPGKAGERGP--PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK 308

Query: 478 SELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPP 537
            E   PG   +  P   R  PG RG R+G  G  +   R   G+  P           PP
Sbjct: 309 GESGSPGENGSPGPMGPRGLPGERG-RTGPAG--AAGARGNDGQPGPA---------GPP 356

Query: 538 GPRG--------GAMSAAGTRSPPGPAESARSRGPRPGWDTP 571
           GP G        GA  A G   P G      ++GPR    TP
Sbjct: 357 GPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 398



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 85/295 (28%), Positives = 95/295 (32%), Gaps = 90/295 (30%)

Query: 308  PHFNGPPAHPGP-GRPSTS-----PCPL-PPSLLCLWVESGT--------PRGRQSLAEG 352
            P   GP   PG  G P  S     P P+ PP L     E G         P GR   A G
Sbjct: 995  PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAA-G 1053

Query: 353  VKRDGGQ-------GLPDVEGAP----------DMGSSGEGAGLEEGSPLRRERAWPPPS 395
            VK D G+       G P   G+P          D G +G    +    P        P  
Sbjct: 1054 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1113

Query: 396  LRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRR 455
             R       E G  GL  K  RG +    L GP G  G    SGP GP    GPP     
Sbjct: 1114 PRGDKGEAGEPGERGL--KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG---- 1167

Query: 456  HLGVQIGRVRVPLGSALPYPARSELAPPGARDALS--PDPERPCPGTRGVRSGREGLLSP 513
                       P+G             P  +D  +  P P  P PG RG RSG  G    
Sbjct: 1168 -----------PVG-------------PSGKDGANGIPGPIGP-PGPRG-RSGETG---- 1197

Query: 514  APRSALGETAPTAQFTFRKVRNPPGPRGGA--MSAAGTRSPPGPAESARSRGPRP 566
             P    G   P           PPGP G    MSA     P       R +GP P
Sbjct: 1198 -PAGPPGNPGPP---------GPPGPPGPGIDMSAFAGLGP-------REKGPDP 1235



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 8/68 (11%)

Query: 514 APRSALGETAPTAQFTFRKVRNPPGPR------GGAMSAAGTRSPPGPAESARSRGPRPG 567
           +P    GE  P            PGP+      G      G + PPGP   A  +GPR  
Sbjct: 77  SPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPR-- 134

Query: 568 WDTPEKGD 575
            D  +KG+
Sbjct: 135 GDRGDKGE 142


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 93/339 (27%), Positives = 124/339 (36%), Gaps = 46/339 (13%)

Query: 257 PPLLGSSLGCPRSGAPRMFIVYHVAAGLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAH 316
           PP LG +     +G          A G  +    G    + PR PP    AP   G   +
Sbjct: 103 PPGLGGNFAAQMAGG-----FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 157

Query: 317 PG-PGRPSTSPC------PLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPD 369
           PG PG P  S        P PP       E+G P G+          G +G P   G P 
Sbjct: 158 PGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP-GKAGERGPPGPQGARGFPGTPGLPG 216

Query: 370 M-GSSG----EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTE 424
           + G  G    +GA  E G+P  +  +  P    +P P     G  GLP +  RG +    
Sbjct: 217 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM----GPRGLPGE--RGRTGPAG 270

Query: 425 LGGPQGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPP 483
             G +G+ G+   +GP GP GP GGP          + G    P G+  P  A+     P
Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG----PTGARGPEGAQGPRGEP 326

Query: 484 GARDALSPDPERPCPGTRGV-----RSGREGLLS----------PAPRSALGETAPTAQF 528
           G   +  P      PGT G+      +G  G+            P P+ A G   P  Q 
Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386

Query: 529 TFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR 565
               +    G +G  G    AG +  PGPA     RG R
Sbjct: 387 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 87/306 (28%), Positives = 103/306 (33%), Gaps = 68/306 (22%)

Query: 301  PPRLGRAPHFNGPPAHPG----PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRD 356
            PP     P   GP   PG    PG    S    PP           P+G       V   
Sbjct: 868  PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG----------PQGLAGQRGIVGLP 917

Query: 357  GGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT----EGGGTGLP 412
            G +G     G P  G SGE    ++G+P       PP  +  P  GLT    E G  G P
Sbjct: 918  GQRGERGFPGLP--GPSGEPG--KQGAPGASGDRGPPGPVGPP--GLTGPAGEPGREGSP 971

Query: 413  SKQRRGPSPKTELGGPQGSLGRASLSG-PFGPGPQGGP-------PSRDRRHLGVQIGRV 464
                 GP  +    G +G  G     G P  PGP G P          DR   G Q    
Sbjct: 972  GAD--GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ---- 1025

Query: 465  RVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVR-----------------SGR 507
              P+G + P  AR    P G R       E   PG RG++                 SG 
Sbjct: 1026 -GPMGPSGPAGARGIQGPQGPRGDKGEAGE---PGERGLKGHRGFTGLQGLPGPPGPSGD 1081

Query: 508  EGLLSPA----PRSALGETAPTAQFTFRKVRNP---PGPRG--GAMSAAGTRSPPGPAES 558
            +G   PA    PR   G   P+ +     +  P   PGPRG  G    AG    PGP   
Sbjct: 1082 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP 1141

Query: 559  ARSRGP 564
                GP
Sbjct: 1142 PGPPGP 1147



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 86/309 (27%), Positives = 105/309 (33%), Gaps = 56/309 (18%)

Query: 298 PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTP--------RG 345
           PR PP         GPP  PG     G+P  +    PP         GTP        RG
Sbjct: 172 PRGPP---------GPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222

Query: 346 RQSLAEGVKRDGGQGLPDVEGAPDMGSSGE----GAGLEEGSPLRRERAWPP-------- 393
              L +G K  G  G P V+G  + GS GE    G     G P  R R  P         
Sbjct: 223 YPGL-DGAK--GEAGAPGVKG--ESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277

Query: 394 ---PSLRTPTPGLTEGGGTGLPSKQ-RRGPSPKTELGGPQGSLG-RASLSGPFGPGPQGG 448
              P    P   +   GG G P     +G +  T   GP+G+ G R     P  PGP G 
Sbjct: 278 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337

Query: 449 PPSRDRRHLGVQIGRVRVP-LGSALPYPA-RSELAPPGARDALSPDPERPCPGTRGVRSG 506
             +     +    G    P +  A  +P  R    P GA   L P  +   PG  G +  
Sbjct: 338 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE 397

Query: 507 REGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPP------GP 555
           +     P P    G   P  +   R  R  PG  G     G   A G R  P      GP
Sbjct: 398 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 457

Query: 556 AESARSRGP 564
             +   RGP
Sbjct: 458 KGAPGERGP 466



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 86/292 (29%), Positives = 101/292 (34%), Gaps = 63/292 (21%)

Query: 299 RSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDG 357
           R P  L      NG P  PG PG P        P           P+G+   +     DG
Sbjct: 464 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG-------DAGPQGKVGPSGAPGEDG 516

Query: 358 GQGLPDVEGAPD----MGSSG-EGAGLEEGSPLRRERAWP-PPSLRTPTPGLTEGGGTGL 411
             G P  +GA      MG  G +GA  E G     E+  P  P LR       E G  G 
Sbjct: 517 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKA--GEKGLPGAPGLRGLPGKDGETGAAGP 574

Query: 412 PSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSA 471
           P     GP+ +    G  G  G   L GP GP  +GG P           G   VP G A
Sbjct: 575 PGPA--GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP-----------GDQGVP-GEA 620

Query: 472 LPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSP----------APRSALGE 521
                       GA   + P  ER  PG RG   G +GL  P           P+ A G 
Sbjct: 621 ------------GAPGLVGPRGERGFPGERG-SPGAQGLQGPRGLPGTPGTDGPKGASGP 667

Query: 522 TAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR--PGWD 569
             P         + PPG +G  G   AAG   P G       +GP   PG D
Sbjct: 668 AGPPG------AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 713



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 80/266 (30%), Positives = 101/266 (37%), Gaps = 40/266 (15%)

Query: 302 PRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGL 361
           P +  AP F GP   PGP + +T P                P+G Q+   G+    G+  
Sbjct: 356 PGIAGAPGFPGPRGPPGP-QGATGPLG--------------PKG-QTGEPGIAGFKGEQG 399

Query: 362 PDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSP 421
           P  E  P       G   EEG   R  R  P        PG  E G  G      RG   
Sbjct: 400 PKGEPGPAGPQGAPGPAGEEGK--RGARGEPGGVGPIGPPG--ERGAPG-----NRGFPG 450

Query: 422 KTELGGPQGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSEL 480
           +  L GP+G+ G    SG  GP G  G P       L    G    P G A P   + ++
Sbjct: 451 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP-GDAGP---QGKV 506

Query: 481 APPGARDALSPDPERPCPGTRGVRSGREGLLS-PAPRSALGETAPTAQFTFRKVRNPPGP 539
            P GA      D     PG +G R G+ G++  P P+ A GE     +   + +   PG 
Sbjct: 507 GPSGAP---GEDGRPGPPGPQGAR-GQPGVMGFPGPKGANGEPGKAGE---KGLPGAPGL 559

Query: 540 RG--GAMSAAGTRSPPGPAESARSRG 563
           RG  G     G   PPGPA  A  RG
Sbjct: 560 RGLPGKDGETGAAGPPGPAGPAGERG 585



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 81/271 (29%), Positives = 95/271 (35%), Gaps = 62/271 (22%)

Query: 312 GPPAHPG----PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGA 367
           G P  PG    PG+   +    PP           P G +         G QGLP   G 
Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPG-------PAGPAGERGEQGAPGPSGFQGLPGPPGP 604

Query: 368 PDMGSSGEGAGL--EEGSP----LRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSP 421
           P  G      G+  E G+P     R ER +P         GL   G  GLP       +P
Sbjct: 605 PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ--GPRGLPG------TP 656

Query: 422 KTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQ-IGRVRVPLGSALPYPARSEL 480
            T+  GP+G+      SGP GP    GPP       G+Q +   R   G A P   R ++
Sbjct: 657 GTD--GPKGA------SGPAGPPGAQGPP-------GLQGMPGERGAAGIAGPKGDRGDV 701

Query: 481 APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPR 540
              G   A   D  R   G  G          P P  A GE              PPGP 
Sbjct: 702 GEKGPEGAPGKDGGRGLTGPIG---------PPGPAGANGEKGEVG---------PPGPA 743

Query: 541 G--GAMSAAGTRSPPGPAESARSRGPRPGWD 569
           G  GA  A G R   GP   A   GP PG D
Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGP-PGAD 773



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 85/297 (28%), Positives = 105/297 (35%), Gaps = 63/297 (21%)

Query: 299 RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRD 356
           + P  L   P  +GP    GP  P  +  P  P L       G P  RG   +A G K D
Sbjct: 647 QGPRGLPGTPGTDGPKGASGPAGPPGAQGP--PGL------QGMPGERGAAGIA-GPKGD 697

Query: 357 GGQ-GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQ 415
            G  G    EGAP  G  G G GL    P+       PP    P     E G  G P   
Sbjct: 698 RGDVGEKGPEGAP--GKDG-GRGLT--GPIG------PPG---PAGANGEKGEVGPP--- 740

Query: 416 RRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRD-------RRHLGVQIGRV---- 464
             GP+      G +G+ G    +GP GP    GPP  D        +    Q G      
Sbjct: 741 --GPAGSA---GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG 795

Query: 465 -RVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRG-----VRSGREGLLSP----- 513
            + P G+  P        P GAR A  P      PG  G       +G  G   P     
Sbjct: 796 PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG 855

Query: 514 --APRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESARSRG 563
              P+ A G++ P  +     ++ P GP G     G    +G   PPGP   A  RG
Sbjct: 856 KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 912



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 78/277 (28%), Positives = 93/277 (33%), Gaps = 69/277 (24%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
            G    PGP  PS +P P  P+ +        P+G +         G QG P   G P  G
Sbjct: 789  GDAGAPGPQGPSGAPGPQGPTGVT------GPKGAR---------GAQGPPGATGFP--G 831

Query: 372  SSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGS 431
            ++G              R  PP S   P P    G       K  RG S      GP G 
Sbjct: 832  AAG--------------RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS------GPPGR 871

Query: 432  LGRASLSGPFGP----------GPQG--GPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
             G   L GP GP          GP G  GPP    + L  Q G V +P         R E
Sbjct: 872  AGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG--PQGLAGQRGIVGLP-------GQRGE 922

Query: 480  LAPPGARDALSPDPERPCPGTRGVRS-----GREGLLSPA----PRSALGETAPTAQFTF 530
               PG         ++  PG  G R      G  GL  PA       + G   P  +   
Sbjct: 923  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982

Query: 531  RKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR 565
              V+   G  G  GA  A G    PGPA     +G R
Sbjct: 983  AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 85/295 (28%), Positives = 95/295 (32%), Gaps = 90/295 (30%)

Query: 308  PHFNGPPAHPGP-GRPSTS-----PCPL-PPSLLCLWVESGT--------PRGRQSLAEG 352
            P   GP   PG  G P  S     P P+ PP L     E G         P GR   A G
Sbjct: 926  PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAA-G 984

Query: 353  VKRDGGQ-------GLPDVEGAP----------DMGSSGEGAGLEEGSPLRRERAWPPPS 395
            VK D G+       G P   G+P          D G +G    +    P        P  
Sbjct: 985  VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1044

Query: 396  LRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRR 455
             R       E G  GL  K  RG +    L GP G  G    SGP GP    GPP     
Sbjct: 1045 PRGDKGEAGEPGERGL--KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG---- 1098

Query: 456  HLGVQIGRVRVPLGSALPYPARSELAPPGARDALS--PDPERPCPGTRGVRSGREGLLSP 513
                       P+G             P  +D  +  P P  P PG RG RSG  G    
Sbjct: 1099 -----------PVG-------------PSGKDGANGIPGPIGP-PGPRG-RSGETG---- 1128

Query: 514  APRSALGETAPTAQFTFRKVRNPPGPRGGA--MSAAGTRSPPGPAESARSRGPRP 566
             P    G   P           PPGP G    MSA     P       R +GP P
Sbjct: 1129 -PAGPPGNPGPP---------GPPGPPGPGIDMSAFAGLGP-------REKGPDP 1166



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 88/345 (25%), Positives = 111/345 (32%), Gaps = 59/345 (17%)

Query: 268 RSGAPRMFIVYHVAAGLPILPPAGHTLRLP-PRSPP-RLGRAPHFNGPPAHPGPGRPSTS 325
           R GAP+  ++  +     +L   G  +R P P+      G      GP   PGP  P+  
Sbjct: 3   RLGAPQTLVLLTLLVAA-VLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGE 61

Query: 326 PCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPL 385
             P           +  PRGR          G  G P   G P +G  G  A    G   
Sbjct: 62  QGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG--GNFAAQMAGGFD 119

Query: 386 RRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGP 445
            +        ++ P   +   G    P      P P+   G P G  G   +SGP GP  
Sbjct: 120 EKAGGAQLGVMQGPMGPMGPRG----PPGPAGAPGPQGFQGNP-GEPGEPGVSGPMGPRG 174

Query: 446 QGGPPSR--------------DRRHLGVQIGRVRVPLGSALP-------YP----ARSEL 480
             GPP +              +R   G Q G    P    LP       YP    A+ E 
Sbjct: 175 PPGPPGKPGDDGEAGKPGKAGERGPPGPQ-GARGFPGTPGLPGVKGHRGYPGLDGAKGEA 233

Query: 481 APPGARDALSPDPERPCPGTRGVRS--GREGLLSPA----PRSALGETAPTAQFTFRKVR 534
             PG +       E   PG  G R   G  G   PA     R   G+  P          
Sbjct: 234 GAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA--------- 284

Query: 535 NPPGPRG--------GAMSAAGTRSPPGPAESARSRGPRPGWDTP 571
            PPGP G        GA  A G   P G      ++GPR    TP
Sbjct: 285 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 329


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 106/360 (29%), Positives = 130/360 (36%), Gaps = 104/360 (28%)

Query: 298  PRSPPRLGRAPHFNGPPAHPG----PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGV 353
            P   P L   P  +GPP HPG    PG       P P       +    PRG +  A+G+
Sbjct: 746  PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGP----IGYPGPRGVKG-ADGI 800

Query: 354  K-------RDGGQGLPDVEGAPDMGSSGE-------GAGLEEGSPLRRERAWP---PPSL 396
            +         G  G P  +G  DMG  G+       G   E+G    + R  P   P  L
Sbjct: 801  RGLKGTKGEKGEDGFPGFKG--DMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL 858

Query: 397  RTP-------TPGLT----------------------EGGGTGLPSKQ----RRGPS-PK 422
              P        PGL                       E GG G P K     +RGP+ P+
Sbjct: 859  GPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPR 918

Query: 423  TELG--------GPQGSLGRASLSGPFG-------------PGPQG--GPPSRD------ 453
             E G        GP+G+ G    +GP G             PGP+G  GPP +D      
Sbjct: 919  GERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHP 978

Query: 454  --RRHLGVQIGRVRV--PLGSALPYPARSELAPPGARDALSPDPERPCPGTRGV--RSGR 507
              R   G Q G+     P G   P     E  P G R    P P  P PG +G+   +G+
Sbjct: 979  GQRGETGFQ-GKTGPPGPPGVVGPQGPTGETGPMGERG--HPGPPGP-PGEQGLPGLAGK 1034

Query: 508  EGLL-SPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGP 564
            EG    P P    G+  P     F   R  PGP G  G     G   PPGPA S   RGP
Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGP 1094



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 81/270 (30%), Positives = 102/270 (37%), Gaps = 34/270 (12%)

Query: 312 GPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGA 367
           GP   PGP    G P     P P   +    E G P G+  L      DG  G P  EG 
Sbjct: 712 GPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG-PLGKPGLPGMPGADGPPGHPGKEGP 770

Query: 368 PDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELG- 426
           P     GE  G     P +    +P P       G+    GT     +   P  K ++G 
Sbjct: 771 P-----GEKGGQGPPGP-QGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGI 824

Query: 427 -GPQGSLGRASLSGPFGP-GPQG-GPPSRDRRHLGV--QIGRVRVPLGSALP-YPARSEL 480
            G +G +G     G  GP GP+G G P+ D   LG   + G++ VP    LP YP R   
Sbjct: 825 KGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVP---GLPGYPGRQ-- 879

Query: 481 APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPR 540
            P G+            PG  G + GR     P PR   G T P  +   R +   PGP+
Sbjct: 880 GPKGSIGFPG------FPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPK 933

Query: 541 G-----GAMSAAGTRSPPGPAESARSRGPR 565
           G     G     G R P GP       GP+
Sbjct: 934 GNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 98/338 (28%), Positives = 121/338 (35%), Gaps = 75/338 (22%)

Query: 289  PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGT-- 342
            P G T    P+ PP     P  +G P HPG     G    +  P PP ++     +G   
Sbjct: 953  PQGPTGFPGPKGPPG---PPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009

Query: 343  ------------PRGRQSLA-----EGVKRDGGQ-GLPDVEGAPDMGSSGEGAGLEE--- 381
                        P G Q L      EG K D G  GLP  +G P +       GL     
Sbjct: 1010 PMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG 1069

Query: 382  GSPLRRERAWPPPSLRTPTPG----LTEGGGTGLPSKQ--RRGPSPKTELG-----GPQG 430
               L+     P P     +PG        G  G+P +   +  P P  E G     GPQG
Sbjct: 1070 ALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG 1129

Query: 431  SLGRASLSGPFG-PGPQG--GPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARD 487
              GR  L GP G PGP G  GPP  D        G +  P G       + E  PPG   
Sbjct: 1130 PAGRDGLQGPVGLPGPAGPVGPPGEDG-----DKGEIGEP-GQKGSKGDKGEQGPPGPTG 1183

Query: 488  ALSPDPERPCPGTRGVRS-----GREGLL----SPAPRSALGETAPTAQFTFRKVRNPPG 538
               P  +   PG  G        G++GL        PR   G   P      + +  PPG
Sbjct: 1184 PQGPIGQ---PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVG---LQGLPGPPG 1237

Query: 539  PRG--GAMSAAGTRSPPGPAESARSRGP--RPGWDTPE 572
             +G  G +   G   PPGP      RGP   PG D P+
Sbjct: 1238 EKGETGDVGQMGPPGPPGP------RGPSGAPGADGPQ 1269



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 85/296 (28%), Positives = 97/296 (32%), Gaps = 73/296 (24%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGG------------- 358
            GPP   GP  P   P P          E G PRG+Q L  G K D G             
Sbjct: 1177 GPPGPTGPQGPIGQPGPSGAD-----GEPG-PRGQQGLF-GQKGDEGPRGFPGPPGPVGL 1229

Query: 359  QGLPDVEGAP----DMGSSGE----GAGLEEGSPLRRERAWPPPSLRTP-------TPGL 403
            QGLP   G      D+G  G     G     G+P       PP  +  P        PG 
Sbjct: 1230 QGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG- 1288

Query: 404  TEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGR 463
             E G  GLP +           GGP G  G     G  GP    GPP   +   G     
Sbjct: 1289 -EAGEPGLPGE-----------GGPPGPKGERGEKGESGPSGAAGPPG-PKGPPGDD--- 1332

Query: 464  VRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETA 523
               P GS  P     +  PPG       D     PG +G         SP P    G + 
Sbjct: 1333 --GPKGSPGPVGFPGDPGPPGEPGPAGQDGP---PGDKGDDGEPGQTGSPGPTGEPGPSG 1387

Query: 524  PTAQFTFRKVRNPPGPRG--------GAMSAAGTRSPPGPAESARSRGP--RPGWD 569
            P  +      R PPGP G        GA   AG   PPG       +G   +PG D
Sbjct: 1388 PPGK------RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD 1437



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 86/285 (30%), Positives = 105/285 (36%), Gaps = 60/285 (21%)

Query: 301  PPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQ 359
            PP     P  +GP   PGP G P     P PP       E G P G+     G K D G+
Sbjct: 1322 PPGPKGPPGDDGPKGSPGPVGFPGD---PGPPG------EPG-PAGQDG-PPGDKGDDGE 1370

Query: 360  GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPP-PSLRTPTPGLT-EGGGTGLPSKQ-- 415
              P   G+P  G +GE      G P +R    P  P  R    G   E G  G P K   
Sbjct: 1371 --PGQTGSP--GPTGEPG--PSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGP 1424

Query: 416  --------RRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP 467
                    + GP     + GP G  G     GP GP    GPP       G++       
Sbjct: 1425 IGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLP----GLK------- 1473

Query: 468  LGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQ 527
             G + P   + E   PG    + P  E+   G RG+  G +G  S  P+   G T P+  
Sbjct: 1474 -GDSGP---KGEKGHPGLIGLIGPPGEQGEKGDRGL-PGPQG--SSGPKGEQGITGPSGP 1526

Query: 528  FTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESARSRGPRPG 567
                    PPGP G     G   A G+  P GP   A   GP PG
Sbjct: 1527 I------GPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGP-PG 1564



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 108/425 (25%), Positives = 137/425 (32%), Gaps = 96/425 (22%)

Query: 289 PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQS 348
           P G T R  P  PP  G      G P   GP  P     P  P+        G P GR+ 
Sbjct: 563 PMGLTGRPGPVGPPGSGG---LKGEPGDVGPQGPRGVQGPPGPA--------GKP-GRRG 610

Query: 349 LAEGVKRDGGQGLPDVEGAP-DMGSSGEGAGL--EEGSPLRRERAWPPPSLRTPTPGLTE 405
            A     DG +G+P   G   D G  G  AGL  E+G      R  P PS     PG   
Sbjct: 611 RAGS---DGARGMPGQTGPKGDRGFDGL-AGLPGEKG-----HRGDPGPSGPPGPPG--- 658

Query: 406 GGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPS--------RDRRHL 457
                      RG   +    G  G  G   L GP GP    GPP           + ++
Sbjct: 659 -------DDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNV 711

Query: 458 GVQ-----IGRVRVPLGSALPYPARSELAPPGARDALS-------PDPERP--CPGTRGV 503
           G Q      G+   P    LP P +  + PPG +  L        P  + P   PG  G 
Sbjct: 712 GPQGEPGPPGQQGNPGAQGLPGP-QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGP 770

Query: 504 RSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-----------GAMSAAGTR-- 550
              + G   P P+  +G   P        +R   G +G           G M   G R  
Sbjct: 771 PGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGE 830

Query: 551 -SPPGPAESARSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSEDVCVVTEYL--WEGN 607
             PPGP       GP+ G   P             D GPL    E   +    L  + G 
Sbjct: 831 IGPPGPRGEDGPEGPK-GRGGP-----------NGDPGPLGPPGEKGKLGVPGLPGYPGR 878

Query: 608 SDPKVGSSDPVIPGTKADK-----------KTKMGPMSEEDKRERRSLGVNPRDCSSLDD 656
             PK     P  PG   +K           + + GP     +R  R +   P    +   
Sbjct: 879 QGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGG 938

Query: 657 SSPSG 661
             P+G
Sbjct: 939 DGPAG 943



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 79/299 (26%), Positives = 101/299 (33%), Gaps = 79/299 (26%)

Query: 314 PAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQS------------LAEGVKR-DGGQG 360
           P+  GPG P+            ++   G PRG +             L EG    +G  G
Sbjct: 427 PSEIGPGMPANQDT--------IYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAG 478

Query: 361 LPDVEGAPDMGSSGE-GAGLEEGSPLR-----RERAWPPPSLRTPTPGLTEGGGTGLPSK 414
           LP   G   MG +G+ G   E G P R      +    PP      P    GGG      
Sbjct: 479 LPGPPGT--MGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDA---- 532

Query: 415 QRRGPSPKTE--------------LGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQ 460
             +GP    +              L GP G +G     GP GP P  G    +   +G Q
Sbjct: 533 GSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGP-PGSGGLKGEPGDVGPQ 591

Query: 461 IGR-VRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGR--EGLLS-PAPR 516
             R V+ P G A           PG R     D  R  PG  G +  R  +GL   P  +
Sbjct: 592 GPRGVQGPPGPA---------GKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEK 642

Query: 517 SALGETAPTAQFTFRKVRNPPGPRG--------GAMSAAGTRSPPGPAESARSRGPRPG 567
              G+  P+          PPGP G        G +   G    PGP      +GP PG
Sbjct: 643 GHRGDPGPS---------GPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGP-PG 691



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 56/164 (34%), Positives = 66/164 (40%), Gaps = 39/164 (23%)

Query: 312  GPPAHPGPGRPSTSPCPL-PPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDM 370
            G P  PGP  P   P P+ PP L  L  +SG P+G +         G  GL  + G P  
Sbjct: 1450 GLPGSPGPDGP---PGPMGPPGLPGLKGDSG-PKGEK---------GHPGLIGLIGPP-- 1494

Query: 371  GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG 430
            G  GE          + +R  P P   +   G  E G TG PS     P P   L GP G
Sbjct: 1495 GEQGE----------KGDRGLPGPQGSSGPKG--EQGITG-PSGPIGPPGPPG-LPGPPG 1540

Query: 431  SLGRASLSGPFGP-------GPQG--GPPSRDRRHLGVQIGRVR 465
              G    SGP GP       GP G  GPP    + L +Q  R R
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTR 1584


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 94/309 (30%), Positives = 111/309 (35%), Gaps = 52/309 (16%)

Query: 282 AGLPILPPAGHTLRLP-PRSPPRLGRAPHFNGPPAHPGP--GRPSTSPCPLPPSLLCLWV 338
           AG P  P        P  R PP L  AP   G    PGP  G+ +  P P PP       
Sbjct: 665 AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP-PGPPGA----- 718

Query: 339 ESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRT 398
            +GTP G Q +       GG G P  +G  D G  G G G + G P +     P   +  
Sbjct: 719 -AGTP-GLQGMPG---ERGGLGSPGPKG--DKGEPG-GPGAD-GVPGKDGPRGPTGPIGP 769

Query: 399 PTPG-----LTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG-------PGPQ 446
           P P        EGG  GLP            + GP+GS G    +GP G       PG  
Sbjct: 770 PGPAGQPGDKGEGGAPGLPG-----------IAGPRGSPGERGETGPPGPAGFPGAPGQN 818

Query: 447 GGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS- 505
           G P  +  R    + G    P G A P        PPG +       ER  PG  G    
Sbjct: 819 GEPGGKGERGAPGEKGEGGPP-GVAGPPGGSGPAGPPGPQGVKG---ERGSPGGPGAAGF 874

Query: 506 -GREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSR 562
            G  GL  P P  + G   P           PPGP G  GA  + G   P G A     +
Sbjct: 875 PGARGL--PGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEK 932

Query: 563 GPRPGWDTP 571
           G  PG   P
Sbjct: 933 G-SPGAQGP 940



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 87/288 (30%), Positives = 101/288 (35%), Gaps = 50/288 (17%)

Query: 289 PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQS 348
           P G  +R  P SP      P  +G P  PG    S  P P  PS          PRG+  
Sbjct: 530 PGGPGMRGMPGSPG----GPGSDGKPGPPGSQGESGRPGPPGPS---------GPRGQPG 576

Query: 349 LAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWP--PPSLRTPTPGLTEG 406
           +       G  G P   G       G G    +G P +     P  PP    PT    + 
Sbjct: 577 VMGFPGPKGNDGAPGKNGE----RGGPGGPGPQGPPGKNGETGPQGPPG---PTGPGGDK 629

Query: 407 GGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG----PGPQGG------PPSRDRRH 456
           G TG P  Q     P T  GGP G  G+    GP G    PG  GG      P  R    
Sbjct: 630 GDTGPPGPQGLQGLPGT--GGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPG 687

Query: 457 LGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPR 516
           L    G +R   G   P   +    PPG      P      PG +G+   R GL SP P+
Sbjct: 688 LAGAPG-LRGGAGPPGPEGGKGAAGPPG------PPGAAGTPGLQGMPGERGGLGSPGPK 740

Query: 517 SALGET-APTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRG 563
              GE   P A      V    GPRG      G   PPGPA     +G
Sbjct: 741 GDKGEPGGPGAD----GVPGKDGPRG----PTGPIGPPGPAGQPGDKG 780



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 83/291 (28%), Positives = 99/291 (34%), Gaps = 51/291 (17%)

Query: 302 PRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGL 361
           P  G  P  NG P  PGP   + +P              G P G+          G +G 
Sbjct: 644 PGTGGPPGENGKPGEPGPKGDAGAP--------------GAPGGKGDAGA----PGERGP 685

Query: 362 PDVEGAPDMGSSGEGAGLEEGSPLRRERAWPP-PSLRTPTPGLT----EGGGTGLPSKQR 416
           P + GAP +       G E G    +  A PP P     TPGL     E GG G P  + 
Sbjct: 686 PGLAGAPGLRGGAGPPGPEGG----KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPK- 740

Query: 417 RGPSPKTELGGP-----QGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSA 471
                K E GGP      G  G    +GP GP    G P          +  +  P GS 
Sbjct: 741 ---GDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP 797

Query: 472 LPYPARSELAPPGARDALSPDPERPCPGTRGVRS--GREGLLSP----APRSALGETAPT 525
                R E  PPG         +   PG +G R   G +G   P     P    G   P 
Sbjct: 798 ---GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP 854

Query: 526 AQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGP-----RPGWDTP 571
                +  R  PG  G A    G R  PGP  S  + GP      PG D P
Sbjct: 855 GPQGVKGERGSPGGPGAA-GFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP 904



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 90/325 (27%), Positives = 113/325 (34%), Gaps = 67/325 (20%)

Query: 289 PAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTPRGRQ 347
           P GH     P  PP +  +P   G     G PG P       PP           P G  
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPG----------PAGAN 422

Query: 348 SLAEGVKRDGGQGLPDVEGAP-DMGSSGEG--AGLEEGSPLRRERAWPPPSLRTPTPGLT 404
             A G++  GG G P   GA  + G  GE   AG+      + E        +  +PG  
Sbjct: 423 G-APGLR--GGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDG------KDGSPG-- 471

Query: 405 EGGGTGLPSKQR-------RGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHL 457
           E G  GLP           RGP+    + G +G  G     GP GP    G P RD    
Sbjct: 472 EPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD---- 527

Query: 458 GVQIG-RVRVPLGSALPYPARSELAPPGAR-DALSPDPERP------------------- 496
           GV  G  +R   GS     +  +  PPG++ ++  P P  P                   
Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587

Query: 497 -CPGTRGVRSGREGLLSPAPRSALGET------APTAQFTFRKVRNPPGPRGGAMSAAGT 549
             PG  G R G  G     P    GET       PT     +    PPGP+ G     GT
Sbjct: 588 GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ-GLQGLPGT 646

Query: 550 RSPPGPAESARSRGPRPGWDTPEKG 574
             PPG  E+ +   P P  D    G
Sbjct: 647 GGPPG--ENGKPGEPGPKGDAGAPG 669



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 89/329 (27%), Positives = 119/329 (36%), Gaps = 62/329 (18%)

Query: 267 PRSGAPRMFIVYHVAAGLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-------P 319
           P++ +P+ +  Y V +G+ +   AG+     P  PP         G P  PG       P
Sbjct: 148 PQNYSPQ-YDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEP 206

Query: 320 GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLP---------DVEGAPDM 370
           G+   S  P PP      +    P G+   +    R G +GLP          + G P M
Sbjct: 207 GQAGPSGPPGPPGA----IGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGM 262

Query: 371 -GSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGP 428
            G  G +G   E+G               T  PGL   G  GLP  +   P P    G P
Sbjct: 263 KGHRGFDGRNGEKG--------------ETGAPGLK--GENGLPG-ENGAPGPMGPRGAP 305

Query: 429 QGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYP--ARSELAPPGAR 486
            G  GR  L G  G     G    D      Q G    P  +  P    A+ E+ P G+ 
Sbjct: 306 -GERGRPGLPGAAGARGNDGARGSDG-----QPGPPGPPGTAGFPGSPGAKGEVGPAGSP 359

Query: 487 DALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAM 544
            +     +R  PG +G  +G +G   P P    G      +          GP G  GA 
Sbjct: 360 GSNGAPGQRGEPGPQG-HAGAQG--PPGPPGINGSPGGKGEM---------GPAGIPGAP 407

Query: 545 SAAGTRSPPGPAESARSRGPRPGWDTPEK 573
              G R PPGPA +  + G R G   P K
Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGK 436



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 89/324 (27%), Positives = 103/324 (31%), Gaps = 70/324 (21%)

Query: 307  APHFNGPPAHPG----------------PGRPSTSPCPLP---------PSLLCLWVESG 341
            +P   GPP  PG                PG P     P P         P    L  E G
Sbjct: 934  SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERG 993

Query: 342  T--PRGRQSLAEGVKRDGGQGLPDVEGAP--DMGSSGEGAGLEEGSPLRRERAWPPPSLR 397
               P+G   LA      G  G P  +G P  D    G+G   E GSP             
Sbjct: 994  PPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSP------------- 1040

Query: 398  TPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG----PGPQGGPPSRD 453
               PG    G  G P     GP+ K+   G  G  G A   GP G    PGPQG  P  D
Sbjct: 1041 -GAPGAP--GHPGPPGPV--GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQG--PRGD 1093

Query: 454  RRHLGVQ-----------IGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRG 502
            +   G +            G    P GS  P   +  +  PG      P      PG  G
Sbjct: 1094 KGETGERGAAGIKGHRGFPGNPGAP-GSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDG 1152

Query: 503  VRSGREGLLS-PAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARS 561
              SG  G +  P PR   GE              PPGP G      G     G A  A  
Sbjct: 1153 T-SGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCG---GVGAAAIAGI 1208

Query: 562  RGPRPGWDTPEKGDHLLSFTMQED 585
             G + G   P  GD  + F +  D
Sbjct: 1209 GGEKAGGFAPYYGDEPMDFKINTD 1232



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 84/326 (25%), Positives = 103/326 (31%), Gaps = 79/326 (24%)

Query: 285 PILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTP 343
           P  PP G   + P   P   G  P  NG P  PG PG P +   P PP +         P
Sbjct: 95  PTRPPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPGSPGS---PGPPGIC-----ESCP 145

Query: 344 RGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGL 403
            G Q+ +                 P   S    +G+  G          PP    P P  
Sbjct: 146 TGPQNYS-----------------PQYDSYDVKSGVAVGGLAGYPGPAGPPG--PPGPPG 186

Query: 404 TEG--GGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQI 461
           T G  G  G P  Q  GP  +    GP G  G     GP GP  + G   R  R      
Sbjct: 187 TSGHPGSPGSPGYQ--GPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP----- 239

Query: 462 GRVRVPLGSALPYPA--------------------RSELAPPGARDALSPDPERPCPGTR 501
           G   +P    +  PA                    + E   PG +       E   PG  
Sbjct: 240 GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM 299

Query: 502 GVRS-----GREGLLSPA-------PRSALGETAPTAQFTFRKVRNPPGPRG-------- 541
           G R      GR GL   A        R + G+  P            PG +G        
Sbjct: 300 GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP 359

Query: 542 GAMSAAGTRSPPGPAESARSRGPRPG 567
           G+  A G R  PGP   A ++GP PG
Sbjct: 360 GSNGAPGQRGEPGPQGHAGAQGP-PG 384


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 99/355 (27%), Positives = 128/355 (36%), Gaps = 96/355 (27%)

Query: 298 PRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVK--- 354
           P+  P L   P  +GPP HPG   P  +     PS     +    PRG + + +G++   
Sbjct: 588 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV-DGIRGLK 646

Query: 355 ----RDGGQGLPDVEGAPDMGSSGE-------GAGLEEGSPLRRERAWP-----PPSL-- 396
                 G  G P  +G  D+G  G+       G+  E+G    + R  P     PP L  
Sbjct: 647 GHKGEKGEDGFPGFKG--DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMG 704

Query: 397 ---RTPTPGLT----------------------EGGGTGLPSKQ----RRGPSPKTELGG 427
              +   PGL                       E G  GL  K      RGP+      G
Sbjct: 705 EKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG 764

Query: 428 PQGSLGRASLSGPFG-------------PGPQG-----------GPPSRD--------RR 455
           P+G+ G++   G  G             PGPQG           GPP +D        R 
Sbjct: 765 PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 824

Query: 456 HLGVQIGRVRV--PLGSALPYPARSELAPPGARDALSPDPERPCPGTRGV--RSGREGLL 511
            +G Q G+     P G   P  A  E  P G R    P P  P PG +G+   +G+EG  
Sbjct: 825 EVGFQ-GKTGPPGPPGVVGPQGAAGETGPMGERG--HPGPPGP-PGEQGLPGTAGKEGTK 880

Query: 512 -SPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRG 563
             P P  A G+  P     F   R  PG  G  G     G   PPGPA S   RG
Sbjct: 881 GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 935



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 96/330 (29%), Positives = 119/330 (36%), Gaps = 81/330 (24%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGT----------- 342
            P+ PP     P  +G P HPG     G    +  P PP ++     +G            
Sbjct: 804  PKGPPG---PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 860

Query: 343  ---PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTP 399
               P G Q L     ++G +G P   GAP  G  G  AGL  G P   ER  P  +    
Sbjct: 861  PPGPPGEQGLPGTAGKEGTKGDPGPPGAP--GKDGP-AGLR-GFP--GERGLPGTA---- 910

Query: 400  TPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPG----PQGGPPSRDRR 455
                   GG GL  K   GPS      G  G  G A   GP GP     PQG P +   +
Sbjct: 911  -------GGPGL--KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 961

Query: 456  HLGVQIG--------RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGR 507
             +  + G         V+ P+G  LP PA     PPG         E   PG +G +  +
Sbjct: 962  GVPGEKGPIGPTGRDGVQGPVG--LPGPA----GPPGVAGEDGDKGEVGDPGQKGTKGNK 1015

Query: 508  EGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTR---SPPGPAESA 559
                 P P   +G   P  Q         PG RG     GA    GTR    PPGP    
Sbjct: 1016 GEHGPPGPPGPIG---PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1072

Query: 560  RSRGPRPGWDTPEKGDHLLSFTMQEDVGPL 589
               GP     + EKG+         DVGP+
Sbjct: 1073 GLPGP-----SGEKGE-------TGDVGPM 1090



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 77/264 (29%), Positives = 96/264 (36%), Gaps = 38/264 (14%)

Query: 310  FNGPPAH------PGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPD 363
            FNGPP        PGP         + P      +    P G +  A     DG QG P 
Sbjct: 1062 FNGPPGPIGLQGLPGPSGEKGETGDVGP------MGPPGPPGPRGPAGPNGADGPQGPPG 1115

Query: 364  VEGAPDMGSSGE-GAGLEEGSP-LRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSP 421
              G  ++G  GE G   E GSP ++ E     P ++ P     E G +G P +    P P
Sbjct: 1116 --GVGNLGPPGEKGEPGESGSPGIQGE-----PGVKGPRGERGEKGESGQPGEPGP-PGP 1167

Query: 422  KTELG--GPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
            K   G  GP+G+ G     G  GP  +GGP  +D        G    P     P P   E
Sbjct: 1168 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK--GDRGEDGEPGQPGSPGPT-GE 1224

Query: 480  LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
              PPG      P      PG+ G + G+     P    A G+T P           P G 
Sbjct: 1225 NGPPGPLGKRGP---AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1281

Query: 540  RG--------GAMSAAGTRSPPGP 555
            RG        G   A G   PPGP
Sbjct: 1282 RGLPGSVGQQGRPGATGQAGPPGP 1305



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 102/383 (26%), Positives = 128/383 (33%), Gaps = 70/383 (18%)

Query: 289 PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPL--PPSLLCLWVESGTPRGR 346
           P G+T R  P   P    +P   G     GP  P   P  L  PP        +G    R
Sbjct: 405 PMGYTGRPGPLGQPG---SPGLKGESGDLGPQGPR-GPQGLTGPPGKAGRRGRAGADGAR 460

Query: 347 QSLAE-GVKRDGG-QGLPDVEGAP----DMGSSG-EGAGLEEGSPLRRERAWPP--PSLR 397
               + GVK D G  GLP + G      D G+ G  G   E+G         P   P   
Sbjct: 461 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 520

Query: 398 TPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG---SLGRASLSGPFG----------PG 444
            P   L   G  G+P     GP     + GPQG   SLG     GP G          PG
Sbjct: 521 GPRGLLGPKGPPGIP-----GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 575

Query: 445 PQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPD-PERPC--PGTR 501
           PQG       +    + G   +P GS  P     +  PPG +    P  P+ P   PG R
Sbjct: 576 PQGAIGPHGEKGPQGKPGLPGMP-GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 634

Query: 502 GVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESA 559
           GV+ G +G+     R   G      +  F   +   G +G  G +   G+R   GP    
Sbjct: 635 GVK-GVDGI-----RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 688

Query: 560 RSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSEDVCVVTEYL--WEGNSDPKVGSSDP 617
              GP                    D GP     E   +    L  + G   PK     P
Sbjct: 689 GRTGP------------------TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 730

Query: 618 VIPGTKADK-----KTKMGPMSE 635
             PG   +K       K GP  E
Sbjct: 731 GFPGASGEKGARGLSGKSGPRGE 753



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 74/275 (26%), Positives = 95/275 (34%), Gaps = 74/275 (26%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRDGGQ-GLPDVEG-- 366
            G P  PGP   +  P PL          +G+P   GRQ   +G K D G  G P   G  
Sbjct: 1214 GQPGSPGPTGENGPPGPLGKR-----GPAGSPGSEGRQG-GKGAKGDPGAIGAPGKTGPV 1267

Query: 367  ---------APDMGSSGEGAGLEEGSPLRRERAWPPPSLRTP-TPGLTEGGGT------- 409
                      PD      G+  ++G P    +A PP  +  P  PGL    G        
Sbjct: 1268 GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHP 1327

Query: 410  ------GLPSKQRRGPSPKTELGGPQGS------LGRASLSGPFGPGPQGGPPSRDRRHL 457
                  G P +Q  G      L GPQGS      +G    SGP GP   GGPP       
Sbjct: 1328 GLIGLIGPPGEQ--GEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP---GGPP------- 1375

Query: 458  GVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREG----LLSP 513
                          LP PA     P GA+ A  P   +   G +G   G  G    ++ P
Sbjct: 1376 -------------GLPGPA----GPKGAKGATGPGGPKGEKGVQG-PPGHPGPPGEVIQP 1417

Query: 514  APRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAG 548
             P     +T  +   +     +   P GGA  + G
Sbjct: 1418 LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452



 Score = 36.6 bits (83), Expect = 0.095
 Identities = 65/234 (27%), Positives = 79/234 (33%), Gaps = 60/234 (25%)

Query: 380 EEGSPLRRERAWPPPSLRTPTPGLTEG---------------GGTGLPSKQRRGPSPKTE 424
           ++ S L R +   P S + PTPG  E                G  GL  K  +G     E
Sbjct: 250 QQPSRLHRPQNQEPQS-QDPTPGEEEEILESSLLPPLEEAAHGPRGL--KGEKGEPAVLE 306

Query: 425 LG----GPQGSLGRASLSGPFG----PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPA 476
            G    GP G  G A L GP G    PGP G P  R         GR  +P     P P 
Sbjct: 307 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG------PPGRAGLPGSDGAPGPP 360

Query: 477 RSELAPP-------GARDALSPDPE--------------RPCPGTRGVRSGREGLL---- 511
            + L  P       G +  +    E              R  PG  G  +GR G L    
Sbjct: 361 GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY-TGRPGPLGQPG 419

Query: 512 SPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRG 563
           SP  +   G+  P      + +  PPG  G  G   A G R  PG       RG
Sbjct: 420 SPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 473



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 16/70 (22%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
            GPP HPGP      P P+              + R+S+      DG + + + E  P  G
Sbjct: 1403 GPPGHPGPPGEVIQPLPIQMP----------KKTRRSV------DGSRLMQEDEAIPTGG 1446

Query: 372  SSGEGAGLEE 381
            + G   GLEE
Sbjct: 1447 APGSPGGLEE 1456


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 99/355 (27%), Positives = 128/355 (36%), Gaps = 96/355 (27%)

Query: 298 PRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVK--- 354
           P+  P L   P  +GPP HPG   P  +     PS     +    PRG + + +G++   
Sbjct: 567 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV-DGIRGLK 625

Query: 355 ----RDGGQGLPDVEGAPDMGSSGE-------GAGLEEGSPLRRERAWP-----PPSL-- 396
                 G  G P  +G  D+G  G+       G+  E+G    + R  P     PP L  
Sbjct: 626 GHKGEKGEDGFPGFKG--DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMG 683

Query: 397 ---RTPTPGLT----------------------EGGGTGLPSKQ----RRGPSPKTELGG 427
              +   PGL                       E G  GL  K      RGP+      G
Sbjct: 684 EKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG 743

Query: 428 PQGSLGRASLSGPFG-------------PGPQG-----------GPPSRD--------RR 455
           P+G+ G++   G  G             PGPQG           GPP +D        R 
Sbjct: 744 PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 803

Query: 456 HLGVQIGRVRV--PLGSALPYPARSELAPPGARDALSPDPERPCPGTRGV--RSGREGLL 511
            +G Q G+     P G   P  A  E  P G R    P P  P PG +G+   +G+EG  
Sbjct: 804 EVGFQ-GKTGPPGPPGVVGPQGAAGETGPMGERG--HPGPPGP-PGEQGLPGTAGKEGTK 859

Query: 512 -SPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRG 563
             P P  A G+  P     F   R  PG  G  G     G   PPGPA S   RG
Sbjct: 860 GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 914



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 96/330 (29%), Positives = 119/330 (36%), Gaps = 81/330 (24%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGT----------- 342
            P+ PP     P  +G P HPG     G    +  P PP ++     +G            
Sbjct: 783  PKGPPG---PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 839

Query: 343  ---PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTP 399
               P G Q L     ++G +G P   GAP  G  G  AGL  G P   ER  P  +    
Sbjct: 840  PPGPPGEQGLPGTAGKEGTKGDPGPPGAP--GKDGP-AGLR-GFP--GERGLPGTA---- 889

Query: 400  TPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPG----PQGGPPSRDRR 455
                   GG GL  K   GPS      G  G  G A   GP GP     PQG P +   +
Sbjct: 890  -------GGPGL--KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 940

Query: 456  HLGVQIG--------RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGR 507
             +  + G         V+ P+G  LP PA     PPG         E   PG +G +  +
Sbjct: 941  GVPGEKGPIGPTGRDGVQGPVG--LPGPA----GPPGVAGEDGDKGEVGDPGQKGTKGNK 994

Query: 508  EGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTR---SPPGPAESA 559
                 P P   +G   P  Q         PG RG     GA    GTR    PPGP    
Sbjct: 995  GEHGPPGPPGPIG---PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1051

Query: 560  RSRGPRPGWDTPEKGDHLLSFTMQEDVGPL 589
               GP     + EKG+         DVGP+
Sbjct: 1052 GLPGP-----SGEKGE-------TGDVGPM 1069



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 77/264 (29%), Positives = 96/264 (36%), Gaps = 38/264 (14%)

Query: 310  FNGPPAH------PGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPD 363
            FNGPP        PGP         + P      +    P G +  A     DG QG P 
Sbjct: 1041 FNGPPGPIGLQGLPGPSGEKGETGDVGP------MGPPGPPGPRGPAGPNGADGPQGPPG 1094

Query: 364  VEGAPDMGSSGE-GAGLEEGSP-LRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSP 421
              G  ++G  GE G   E GSP ++ E     P ++ P     E G +G P +    P P
Sbjct: 1095 --GVGNLGPPGEKGEPGESGSPGIQGE-----PGVKGPRGERGEKGESGQPGEPGP-PGP 1146

Query: 422  KTELG--GPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
            K   G  GP+G+ G     G  GP  +GGP  +D        G    P     P P   E
Sbjct: 1147 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK--GDRGEDGEPGQPGSPGPT-GE 1203

Query: 480  LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
              PPG      P      PG+ G + G+     P    A G+T P           P G 
Sbjct: 1204 NGPPGPLGKRGP---AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1260

Query: 540  RG--------GAMSAAGTRSPPGP 555
            RG        G   A G   PPGP
Sbjct: 1261 RGLPGSVGQQGRPGATGQAGPPGP 1284



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 102/383 (26%), Positives = 128/383 (33%), Gaps = 70/383 (18%)

Query: 289 PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPL--PPSLLCLWVESGTPRGR 346
           P G+T R  P   P    +P   G     GP  P   P  L  PP        +G    R
Sbjct: 384 PMGYTGRPGPLGQPG---SPGLKGESGDLGPQGPR-GPQGLTGPPGKAGRRGRAGADGAR 439

Query: 347 QSLAE-GVKRDGG-QGLPDVEGAP----DMGSSG-EGAGLEEGSPLRRERAWPP--PSLR 397
               + GVK D G  GLP + G      D G+ G  G   E+G         P   P   
Sbjct: 440 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499

Query: 398 TPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG---SLGRASLSGPFG----------PG 444
            P   L   G  G+P     GP     + GPQG   SLG     GP G          PG
Sbjct: 500 GPRGLLGPKGPPGIP-----GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 554

Query: 445 PQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPD-PERPC--PGTR 501
           PQG       +    + G   +P GS  P     +  PPG +    P  P+ P   PG R
Sbjct: 555 PQGAIGPHGEKGPQGKPGLPGMP-GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 613

Query: 502 GVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESA 559
           GV+ G +G+     R   G      +  F   +   G +G  G +   G+R   GP    
Sbjct: 614 GVK-GVDGI-----RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 667

Query: 560 RSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSEDVCVVTEYL--WEGNSDPKVGSSDP 617
              GP                    D GP     E   +    L  + G   PK     P
Sbjct: 668 GRTGP------------------TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 709

Query: 618 VIPGTKADK-----KTKMGPMSE 635
             PG   +K       K GP  E
Sbjct: 710 GFPGASGEKGARGLSGKSGPRGE 732



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 74/275 (26%), Positives = 95/275 (34%), Gaps = 74/275 (26%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRDGGQ-GLPDVEG-- 366
            G P  PGP   +  P PL          +G+P   GRQ   +G K D G  G P   G  
Sbjct: 1193 GQPGSPGPTGENGPPGPLGKR-----GPAGSPGSEGRQG-GKGAKGDPGAIGAPGKTGPV 1246

Query: 367  ---------APDMGSSGEGAGLEEGSPLRRERAWPPPSLRTP-TPGLTEGGGT------- 409
                      PD      G+  ++G P    +A PP  +  P  PGL    G        
Sbjct: 1247 GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHP 1306

Query: 410  ------GLPSKQRRGPSPKTELGGPQGS------LGRASLSGPFGPGPQGGPPSRDRRHL 457
                  G P +Q  G      L GPQGS      +G    SGP GP   GGPP       
Sbjct: 1307 GLIGLIGPPGEQ--GEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP---GGPP------- 1354

Query: 458  GVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREG----LLSP 513
                          LP PA     P GA+ A  P   +   G +G   G  G    ++ P
Sbjct: 1355 -------------GLPGPA----GPKGAKGATGPGGPKGEKGVQG-PPGHPGPPGEVIQP 1396

Query: 514  APRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAG 548
             P     +T  +   +     +   P GGA  + G
Sbjct: 1397 LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 48/168 (28%), Positives = 57/168 (33%), Gaps = 38/168 (22%)

Query: 427 GPQGSLGRASLSGPFG----PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAP 482
           GP G  G A L GP G    PGP G P  R         GR  +P     P P  + L  
Sbjct: 292 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERG------PPGRAGLPGSDGAPGPPGTSLML 345

Query: 483 P-------GARDALSPDPE--------------RPCPGTRGVRSGREGLL----SPAPRS 517
           P       G +  +    E              R  PG  G  +GR G L    SP  + 
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY-TGRPGPLGQPGSPGLKG 404

Query: 518 ALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRG 563
             G+  P      + +  PPG  G  G   A G R  PG       RG
Sbjct: 405 ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 452



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 16/70 (22%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
            GPP HPGP      P P+              + R+S+      DG + + + E  P  G
Sbjct: 1382 GPPGHPGPPGEVIQPLPIQMP----------KKTRRSV------DGSRLMQEDEAIPTGG 1425

Query: 372  SSGEGAGLEE 381
            + G   GLEE
Sbjct: 1426 APGSPGGLEE 1435


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 99/355 (27%), Positives = 128/355 (36%), Gaps = 96/355 (27%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVK--- 354
            P+  P L   P  +GPP HPG   P  +     PS     +    PRG + + +G++   
Sbjct: 674  PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV-DGIRGLK 732

Query: 355  ----RDGGQGLPDVEGAPDMGSSGE-------GAGLEEGSPLRRERAWP-----PPSL-- 396
                  G  G P  +G  D+G  G+       G+  E+G    + R  P     PP L  
Sbjct: 733  GHKGEKGEDGFPGFKG--DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMG 790

Query: 397  ---RTPTPGLT----------------------EGGGTGLPSKQ----RRGPSPKTELGG 427
               +   PGL                       E G  GL  K      RGP+      G
Sbjct: 791  EKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG 850

Query: 428  PQGSLGRASLSGPFG-------------PGPQG-----------GPPSRD--------RR 455
            P+G+ G++   G  G             PGPQG           GPP +D        R 
Sbjct: 851  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 910

Query: 456  HLGVQIGRVRV--PLGSALPYPARSELAPPGARDALSPDPERPCPGTRGV--RSGREGLL 511
             +G Q G+     P G   P  A  E  P G R    P P  P PG +G+   +G+EG  
Sbjct: 911  EVGFQ-GKTGPPGPPGVVGPQGAAGETGPMGERG--HPGPPGP-PGEQGLPGTAGKEGTK 966

Query: 512  -SPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRG 563
              P P  A G+  P     F   R  PG  G  G     G   PPGPA S   RG
Sbjct: 967  GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 1021



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 96/330 (29%), Positives = 119/330 (36%), Gaps = 81/330 (24%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGT----------- 342
            P+ PP     P  +G P HPG     G    +  P PP ++     +G            
Sbjct: 890  PKGPPG---PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 946

Query: 343  ---PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTP 399
               P G Q L     ++G +G P   GAP  G  G  AGL  G P   ER  P  +    
Sbjct: 947  PPGPPGEQGLPGTAGKEGTKGDPGPPGAP--GKDGP-AGLR-GFP--GERGLPGTA---- 996

Query: 400  TPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPG----PQGGPPSRDRR 455
                   GG GL  K   GPS      G  G  G A   GP GP     PQG P +   +
Sbjct: 997  -------GGPGL--KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEK 1047

Query: 456  HLGVQIG--------RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGR 507
             +  + G         V+ P+G  LP PA     PPG         E   PG +G +  +
Sbjct: 1048 GVPGEKGPIGPTGRDGVQGPVG--LPGPA----GPPGVAGEDGDKGEVGDPGQKGTKGNK 1101

Query: 508  EGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTR---SPPGPAESA 559
                 P P   +G   P  Q         PG RG     GA    GTR    PPGP    
Sbjct: 1102 GEHGPPGPPGPIG---PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1158

Query: 560  RSRGPRPGWDTPEKGDHLLSFTMQEDVGPL 589
               GP     + EKG+         DVGP+
Sbjct: 1159 GLPGP-----SGEKGE-------TGDVGPM 1176



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 77/264 (29%), Positives = 96/264 (36%), Gaps = 38/264 (14%)

Query: 310  FNGPPAH------PGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPD 363
            FNGPP        PGP         + P      +    P G +  A     DG QG P 
Sbjct: 1148 FNGPPGPIGLQGLPGPSGEKGETGDVGP------MGPPGPPGPRGPAGPNGADGPQGPPG 1201

Query: 364  VEGAPDMGSSGE-GAGLEEGSP-LRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSP 421
              G  ++G  GE G   E GSP ++ E     P ++ P     E G +G P +    P P
Sbjct: 1202 --GVGNLGPPGEKGEPGESGSPGIQGE-----PGVKGPRGERGEKGESGQPGEPGP-PGP 1253

Query: 422  KTELG--GPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
            K   G  GP+G+ G     G  GP  +GGP  +D        G    P     P P   E
Sbjct: 1254 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK--GDRGEDGEPGQPGSPGPT-GE 1310

Query: 480  LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
              PPG      P      PG+ G + G+     P    A G+T P           P G 
Sbjct: 1311 NGPPGPLGKRGP---AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1367

Query: 540  RG--------GAMSAAGTRSPPGP 555
            RG        G   A G   PPGP
Sbjct: 1368 RGLPGSVGQQGRPGATGQAGPPGP 1391



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 102/383 (26%), Positives = 128/383 (33%), Gaps = 70/383 (18%)

Query: 289 PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPL--PPSLLCLWVESGTPRGR 346
           P G+T R  P   P    +P   G     GP  P   P  L  PP        +G    R
Sbjct: 491 PMGYTGRPGPLGQPG---SPGLKGESGDLGPQGPR-GPQGLTGPPGKAGRRGRAGADGAR 546

Query: 347 QSLAE-GVKRDGG-QGLPDVEGAP----DMGSSG-EGAGLEEGSPLRRERAWPP--PSLR 397
               + GVK D G  GLP + G      D G+ G  G   E+G         P   P   
Sbjct: 547 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 606

Query: 398 TPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG---SLGRASLSGPFG----------PG 444
            P   L   G  G+P     GP     + GPQG   SLG     GP G          PG
Sbjct: 607 GPRGLLGPKGPPGIP-----GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 661

Query: 445 PQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPD-PERPC--PGTR 501
           PQG       +    + G   +P GS  P     +  PPG +    P  P+ P   PG R
Sbjct: 662 PQGAIGPHGEKGPQGKPGLPGMP-GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720

Query: 502 GVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESA 559
           GV+ G +G+     R   G      +  F   +   G +G  G +   G+R   GP    
Sbjct: 721 GVK-GVDGI-----RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 774

Query: 560 RSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSEDVCVVTEYL--WEGNSDPKVGSSDP 617
              GP                    D GP     E   +    L  + G   PK     P
Sbjct: 775 GRTGP------------------TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 816

Query: 618 VIPGTKADK-----KTKMGPMSE 635
             PG   +K       K GP  E
Sbjct: 817 GFPGASGEKGARGLSGKSGPRGE 839



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 74/275 (26%), Positives = 95/275 (34%), Gaps = 74/275 (26%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRDGGQ-GLPDVEG-- 366
            G P  PGP   +  P PL          +G+P   GRQ   +G K D G  G P   G  
Sbjct: 1300 GQPGSPGPTGENGPPGPLGKR-----GPAGSPGSEGRQG-GKGAKGDPGAIGAPGKTGPV 1353

Query: 367  ---------APDMGSSGEGAGLEEGSPLRRERAWPPPSLRTP-TPGLTEGGGT------- 409
                      PD      G+  ++G P    +A PP  +  P  PGL    G        
Sbjct: 1354 GPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHP 1413

Query: 410  ------GLPSKQRRGPSPKTELGGPQGS------LGRASLSGPFGPGPQGGPPSRDRRHL 457
                  G P +Q  G      L GPQGS      +G    SGP GP   GGPP       
Sbjct: 1414 GLIGLIGPPGEQ--GEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP---GGPP------- 1461

Query: 458  GVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREG----LLSP 513
                          LP PA     P GA+ A  P   +   G +G   G  G    ++ P
Sbjct: 1462 -------------GLPGPA----GPKGAKGATGPGGPKGEKGVQG-PPGHPGPPGEVIQP 1503

Query: 514  APRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAG 548
             P     +T  +   +     +   P GGA  + G
Sbjct: 1504 LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 67/241 (27%), Positives = 80/241 (33%), Gaps = 49/241 (20%)

Query: 358 GQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRR 417
           G+G  D    P   + G G    E + L      P  S  T   G    G  GL  K  +
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELG-----PALSAETAHSGAAAHGPRGL--KGEK 385

Query: 418 GPSPKTELG----GPQGSLGRASLSGPFG----PGPQGGPPSRDRRHLGVQIGRVRVPLG 469
           G     E G    GP G  G A L GP G    PGP G P  R         GR  +P  
Sbjct: 386 GEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG------PPGRAGLPGS 439

Query: 470 SALPYPARSELAPP-------GARDALSPDPE--------------RPCPGTRGVRSGRE 508
              P P  + L  P       G +  +    E              R  PG  G  +GR 
Sbjct: 440 DGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY-TGRP 498

Query: 509 GLL----SPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSR 562
           G L    SP  +   G+  P      + +  PPG  G  G   A G R  PG       R
Sbjct: 499 GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDR 558

Query: 563 G 563
           G
Sbjct: 559 G 559



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 16/70 (22%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
            GPP HPGP      P P+              + R+S+      DG + + + E  P  G
Sbjct: 1489 GPPGHPGPPGEVIQPLPIQMP----------KKTRRSV------DGSRLMQEDEAIPTGG 1532

Query: 372  SSGEGAGLEE 381
            + G   GLEE
Sbjct: 1533 APGSPGGLEE 1542


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 94/328 (28%), Positives = 120/328 (36%), Gaps = 60/328 (18%)

Query: 285  PILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPR 344
            PI PP        P+  P L   P  +GPP HPG    S     L P      +    PR
Sbjct: 719  PIGPPG----EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR 774

Query: 345  GRQSLAEGVK-------RDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLR 397
            G +  A+GV+         G  G P  +G  DMG  G+   + +  P   +    P    
Sbjct: 775  GVKG-ADGVRGLKGSKGEKGEDGFPGFKG--DMGLKGDRGEVGQIGPRGEDGPEGPKGRA 831

Query: 398  TPT--PGLT----EGGGTGLPS----KQRRGPSPKTEL------GGPQGSLGRASLSGPF 441
             PT  PG +    E G  G+P       R+GP   T         G +G+ G A   GP 
Sbjct: 832  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR 891

Query: 442  GP-GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALS-PDPERP--- 496
            G  GP G   SR  R    + G      G   P P   E  P G +  +  P P+ P   
Sbjct: 892  GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPKGPPGP 950

Query: 497  --------CPGTRGVRSGREGLLSP-------APRSALGETAPTAQFTFRKVRNPPGPRG 541
                     PG RG  +G +G   P        P+   GET P  +   R    PPGP G
Sbjct: 951  PGKDGLPGHPGQRG-ETGFQGKTGPPGPGGVVGPQGPTGETGPIGE---RGHPGPPGPPG 1006

Query: 542  -----GAMSAAGTRSPPGPAESARSRGP 564
                 GA    G +  PGP   +   GP
Sbjct: 1007 EQGLPGAAGKEGAKGDPGPQGISGKDGP 1034



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 90/331 (27%), Positives = 108/331 (32%), Gaps = 75/331 (22%)

Query: 283  GLPILP-PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVES 340
            GLP  P   G T       PP  G      GP    GP G       P PP       E 
Sbjct: 955  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG------EQ 1008

Query: 341  GTPRGRQSLAEGVKRDGG-------------------QGLPDVEGAPDM--GSSGEGAGL 379
            G P       EG K D G                   +GLP  +GAP +  G   +G   
Sbjct: 1009 GLPGAAGK--EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1066

Query: 380  EEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSG 439
              GSP  R  A     +  P  G     G   P+ ++  P  K    GPQG  GR  + G
Sbjct: 1067 PVGSPGERGSAGTAGPIGLP--GRPGPQGPPGPAGEKGAPGEK----GPQGPAGRDGVQG 1120

Query: 440  PFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCP 498
            P G PGP G                   P GS      + E+  PG + +     E   P
Sbjct: 1121 PVGLPGPAG-------------------PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1161

Query: 499  GTRGVRS--GREGLL----SPAPRSALGETAPTAQFTFRKVRNPPGPRG----------- 541
            G  G++   G  G+      P PR   G          R    PPGP G           
Sbjct: 1162 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1221

Query: 542  GAMSAAGTRSPPGPAESARSRGPRPGWDTPE 572
            G     G   PPGP      +GP  G D P+
Sbjct: 1222 GENGDVGPMGPPGPPGPRGPQGPN-GADGPQ 1251



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 81/277 (29%), Positives = 99/277 (35%), Gaps = 57/277 (20%)

Query: 312 GPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGA 367
           GP   PGP    G P     P P   +    E G P+G+  LA     DG  G P  EG 
Sbjct: 694 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG-PQGKPGLAGLPGADGPPGHPGKEG- 751

Query: 368 PDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT-------EGGGTGLPS------- 413
                SGE   L    P +    +P P       G+        E G  G P        
Sbjct: 752 ----QSGEKGALGPPGP-QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 806

Query: 414 KQRRGP----SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLG 469
           K  RG      P+ E  GP+G  GRA  +G  GP  Q G           + G++ VP  
Sbjct: 807 KGDRGEVGQIGPRGE-DGPEGPKGRAGPTGDPGPSGQAG-----------EKGKLGVP-- 852

Query: 470 SALP-YPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQF 528
             LP YP R    P G+            PG  G +  R     P PR   G T P    
Sbjct: 853 -GLPGYPGRQ--GPKGSTGFPG------FPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 903

Query: 529 TFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPR 565
             R     PGP+G     +G   PPGP      +GP+
Sbjct: 904 GARGPTGKPGPKG----TSGGDGPPGPPGERGPQGPQ 936



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 71/260 (27%), Positives = 87/260 (33%), Gaps = 61/260 (23%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
            GPP  PGP  P                 +  P+G       V   G +G P   G P  G
Sbjct: 1231 GPPGPPGPRGPQGPN------------GADGPQGPPGSVGSVGGVGEKGEPGEAGNP--G 1276

Query: 372  SSGE-GAGLEEGSPLRRERAWPPPSLRTPTPGLTEG--------GGTGLPSKQ----RRG 418
              GE G G  +G    +  A PP +   P      G        G  G P         G
Sbjct: 1277 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1336

Query: 419  PSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARS 478
            P+ +  +GG +G  G     GP GP  + GPP                P G         
Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG---------------PPG--------- 1372

Query: 479  ELAPPGARDALSPDPERPCPGTRGVRSGREGLLSP-APRSALGETAPTAQFTFRKVRNPP 537
            +  PPGA  A     E+   G  G   G  G   P  P+   G+  P        +R  P
Sbjct: 1373 KRGPPGAAGAEGRQGEKGAKGEAGA-EGPPGKTGPVGPQGPAGKPGPEG------LRGIP 1425

Query: 538  GPRG--GAMSAAGTRSPPGP 555
            GP G  G   AAG   PPGP
Sbjct: 1426 GPVGEQGLPGAAGQDGPPGP 1445



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 81/287 (28%), Positives = 100/287 (34%), Gaps = 58/287 (20%)

Query: 289  PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQ 347
            P G         PP     P   GPP   GP G P     P  P           P G  
Sbjct: 1286 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG----------PPGEP 1335

Query: 348  SLA--EGVKRDGGQ-GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT 404
              A  +GV  D G+ G P   G P  G SGE      G P        PP  R P     
Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPP--GPSGEA-----GPP-------GPPGKRGPP---- 1377

Query: 405  EGGGTGLPSKQ-RRGPSPKTELGGPQGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIG 462
              G  G   +Q  +G   +    GP G       +GP GP GP G P     R +   +G
Sbjct: 1378 --GAAGAEGRQGEKGAKGEAGAEGPPGK------TGPVGPQGPAGKPGPEGLRGIPGPVG 1429

Query: 463  RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS--GREGLLSPAPRSALG 520
               +P G+A        + PPG    L  D     PG++G +   G  GL+ P      G
Sbjct: 1430 EQGLP-GAAGQDGPPGPMGPPGL-PGLKGD-----PGSKGEKGHPGLIGLIGPP-----G 1477

Query: 521  ETAPTAQFTFRKVRNPPGPR--GGAMSAAGTRSPPGPAESARSRGPR 565
            E            +  PG +  GG    AG   PPGP      +GP+
Sbjct: 1478 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1524



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 80/291 (27%), Positives = 100/291 (34%), Gaps = 66/291 (22%)

Query: 301  PPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQ 359
            PP     P  +GP  +PGP G P     P PP       E G P G+  +      DG  
Sbjct: 1304 PPGAKGPPGDDGPKGNPGPVGFPGD---PGPPG------EPG-PAGQDGVGGDKGEDGDP 1353

Query: 360  GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSL----RTPTPGLT-EGGGTGLPSK 414
            G P   G P  G SGE      G P    +  PP +     R    G   E G  G P K
Sbjct: 1354 GQP---GPP--GPSGEA-----GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1403

Query: 415  Q----------RRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRV 464
                       + GP     + GP G  G    +G  GP    GPP          +  +
Sbjct: 1404 TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG---------LPGL 1454

Query: 465  RVPLGSALPYPARSELAPPGARDALSPDPE------RPCPGTRGVRSGREGLLSPAPRSA 518
            +   GS      + E   PG    + P  E      R  PGT+G    +     P P   
Sbjct: 1455 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1508

Query: 519  LGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPG 567
            LG   P        +  P GP+G  G+   AG +   G      S GP PG
Sbjct: 1509 LGPPGPPG------LPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP-PG 1552



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 90/342 (26%), Positives = 110/342 (32%), Gaps = 89/342 (26%)

Query: 286 ILPPAGHTLRLPPRSPPRLGRAPHFNGPPAH--------PGPGRPSTSPCPLPPSLLCLW 337
           IL  A   LR PP      GR     GP +         PGP  P     P  P+     
Sbjct: 531 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT----- 585

Query: 338 VESGTP--RGRQSLAEGVKRDGGQGLPDVEGAP-DMGSSG-EGAGLEEGSPLRRERAWPP 393
              G P  RGR         DGG+G+P   GA  D G  G  G   ++G    R    PP
Sbjct: 586 ---GKPGKRGRPGA------DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 636

Query: 394 --------------------PSLRTPTPGLTEGGGTGLPSKQRRG-----PSPKTELG-- 426
                               P    P   L   G  G P +         P PK  +G  
Sbjct: 637 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 696

Query: 427 ------GPQGSLGRASLSGPFGP-------GPQG-----------GPPSRDRRHLGVQIG 462
                 G QG+ G   L GP GP       GPQG           GPP    +    Q G
Sbjct: 697 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE--GQSG 754

Query: 463 RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLS-PAPRSALGE 521
                 G+  P   +  +  PG R     D  R   G++G   G +G           G+
Sbjct: 755 E----KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG-EKGEDGFPGFKGDMGLKGD 809

Query: 522 TAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRG 563
                Q   R    P GP+G     AG    PGP+  A  +G
Sbjct: 810 RGEVGQIGPRGEDGPEGPKG----RAGPTGDPGPSGQAGEKG 847



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 89/336 (26%), Positives = 108/336 (32%), Gaps = 75/336 (22%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGV 353
            P+ PP    +P   G     GP    GRP     P P        E G P G +      
Sbjct: 1061 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG------EKGAP-GEKGPQGPA 1113

Query: 354  KRDGGQGLPDVEG-APDMGSSGE-GAGLEEGSPLRR-------ERAWP-PPSLRTPT--P 401
             RDG QG   + G A   GS GE G   E G P ++       E   P PP L+ P   P
Sbjct: 1114 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1173

Query: 402  GLTEGGGTGLPSKQR-----------RG-------------PSPKTELG----------- 426
            G+  G G   P  Q+           RG             P P  E G           
Sbjct: 1174 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1233

Query: 427  ---GPQGSLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVP--LGSALPYPARSEL 480
               GP+G  G     GP G PG  G       +    + G    P   G   P   R E 
Sbjct: 1234 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1293

Query: 481  APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVR------ 534
               G   A  P   +  PG  G +     +  P      GE  P  Q      +      
Sbjct: 1294 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1353

Query: 535  ---NPPGPRG--GAMSAAGTRSPPGPAESARSRGPR 565
                PPGP G  G     G R PPG A +   +G +
Sbjct: 1354 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1389



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 71/279 (25%), Positives = 91/279 (32%), Gaps = 45/279 (16%)

Query: 301 PPRLGRAPHFNGPPAHPGPGRPSTSPCPL-PPSLLCLWVESGTPRGRQSLAEGVKRDGGQ 359
           PP         GPP   GP  P   P    PP    L    G P    ++     R GG 
Sbjct: 455 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 514

Query: 360 GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGP 419
           G    +G        +   + + + +   R  P P   T  PG   G G+     +   P
Sbjct: 515 GS---KGPTISAQEAQAQAILQQARIAL-RGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 570

Query: 420 SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
            P+    GP+G      + GP  PGP G P  R         GR     G  +P      
Sbjct: 571 GPQ----GPRG------VQGP--PGPTGKPGKR---------GRPGADGGRGMP------ 603

Query: 480 LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
              PGA+     D     PG +G R  R     P P    G      +   R +    GP
Sbjct: 604 -GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 662

Query: 540 RG-----------GAMSAAGTRSPPGPAESARSRGPRPG 567
           RG           G    AG   PPGP  +   +G  PG
Sbjct: 663 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG-EPG 700



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/213 (30%), Positives = 81/213 (38%), Gaps = 20/213 (9%)

Query: 358 GQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRR 417
           G G+P      +   +G GA  E+G         P   +  P       G  G P  Q  
Sbjct: 414 GPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQ-- 471

Query: 418 GPSPKTELGGPQGSLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPA 476
           GP+      G +G  GR  L G  G PGP G       R+ G      + P  SA    A
Sbjct: 472 GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG---DGSKGPTISAQEAQA 528

Query: 477 RSELAPPGARDALSPDPERPCPGTRGVRSGREGLLS-PAPRSALGETAPTAQFTFRKVRN 535
           ++ L    AR AL     R  PG  G+ +GR G +  P    A GE+        R V+ 
Sbjct: 529 QAILQQ--ARIAL-----RGPPGPMGL-TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 580

Query: 536 PPGPRG-----GAMSAAGTRSPPGPAESARSRG 563
           PPGP G     G   A G R  PG   +   RG
Sbjct: 581 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 613


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 94/328 (28%), Positives = 120/328 (36%), Gaps = 60/328 (18%)

Query: 285 PILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPR 344
           PI PP        P+  P L   P  +GPP HPG    S     L P      +    PR
Sbjct: 668 PIGPPG----EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR 723

Query: 345 GRQSLAEGVK-------RDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLR 397
           G +  A+GV+         G  G P  +G  DMG  G+   + +  P   +    P    
Sbjct: 724 GVKG-ADGVRGLKGSKGEKGEDGFPGFKG--DMGLKGDRGEVGQIGPRGEDGPEGPKGRA 780

Query: 398 TPT--PGLT----EGGGTGLPS----KQRRGPSPKTEL------GGPQGSLGRASLSGPF 441
            PT  PG +    E G  G+P       R+GP   T         G +G+ G A   GP 
Sbjct: 781 GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR 840

Query: 442 GP-GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALS-PDPERP--- 496
           G  GP G   SR  R    + G      G   P P   E  P G +  +  P P+ P   
Sbjct: 841 GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPKGPPGP 899

Query: 497 --------CPGTRGVRSGREGLLSP-------APRSALGETAPTAQFTFRKVRNPPGPRG 541
                    PG RG  +G +G   P        P+   GET P  +   R    PPGP G
Sbjct: 900 PGKDGLPGHPGQRG-ETGFQGKTGPPGPGGVVGPQGPTGETGPIGE---RGHPGPPGPPG 955

Query: 542 -----GAMSAAGTRSPPGPAESARSRGP 564
                GA    G +  PGP   +   GP
Sbjct: 956 EQGLPGAAGKEGAKGDPGPQGISGKDGP 983



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 90/331 (27%), Positives = 108/331 (32%), Gaps = 75/331 (22%)

Query: 283  GLPILP-PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVES 340
            GLP  P   G T       PP  G      GP    GP G       P PP       E 
Sbjct: 904  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG------EQ 957

Query: 341  GTPRGRQSLAEGVKRDGG-------------------QGLPDVEGAPDM--GSSGEGAGL 379
            G P       EG K D G                   +GLP  +GAP +  G   +G   
Sbjct: 958  GLPGAAGK--EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1015

Query: 380  EEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSG 439
              GSP  R  A     +  P  G     G   P+ ++  P  K    GPQG  GR  + G
Sbjct: 1016 PVGSPGERGSAGTAGPIGLP--GRPGPQGPPGPAGEKGAPGEK----GPQGPAGRDGVQG 1069

Query: 440  PFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCP 498
            P G PGP G                   P GS      + E+  PG + +     E   P
Sbjct: 1070 PVGLPGPAG-------------------PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1110

Query: 499  GTRGVRS--GREGLL----SPAPRSALGETAPTAQFTFRKVRNPPGPRG----------- 541
            G  G++   G  G+      P PR   G          R    PPGP G           
Sbjct: 1111 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170

Query: 542  GAMSAAGTRSPPGPAESARSRGPRPGWDTPE 572
            G     G   PPGP      +GP  G D P+
Sbjct: 1171 GENGDVGPMGPPGPPGPRGPQGPN-GADGPQ 1200



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 81/277 (29%), Positives = 99/277 (35%), Gaps = 57/277 (20%)

Query: 312 GPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGA 367
           GP   PGP    G P     P P   +    E G P+G+  LA     DG  G P  EG 
Sbjct: 643 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG-PQGKPGLAGLPGADGPPGHPGKEG- 700

Query: 368 PDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT-------EGGGTGLPS------- 413
                SGE   L    P +    +P P       G+        E G  G P        
Sbjct: 701 ----QSGEKGALGPPGP-QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 755

Query: 414 KQRRGP----SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLG 469
           K  RG      P+ E  GP+G  GRA  +G  GP  Q G           + G++ VP  
Sbjct: 756 KGDRGEVGQIGPRGE-DGPEGPKGRAGPTGDPGPSGQAG-----------EKGKLGVP-- 801

Query: 470 SALP-YPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQF 528
             LP YP R    P G+            PG  G +  R     P PR   G T P    
Sbjct: 802 -GLPGYPGRQ--GPKGSTGFPG------FPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 852

Query: 529 TFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPR 565
             R     PGP+G     +G   PPGP      +GP+
Sbjct: 853 GARGPTGKPGPKG----TSGGDGPPGPPGERGPQGPQ 885



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 71/260 (27%), Positives = 87/260 (33%), Gaps = 61/260 (23%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
            GPP  PGP  P                 +  P+G       V   G +G P   G P  G
Sbjct: 1180 GPPGPPGPRGPQGPN------------GADGPQGPPGSVGSVGGVGEKGEPGEAGNP--G 1225

Query: 372  SSGE-GAGLEEGSPLRRERAWPPPSLRTPTPGLTEG--------GGTGLPSKQ----RRG 418
              GE G G  +G    +  A PP +   P      G        G  G P         G
Sbjct: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285

Query: 419  PSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARS 478
            P+ +  +GG +G  G     GP GP  + GPP                P G         
Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG---------------PPG--------- 1321

Query: 479  ELAPPGARDALSPDPERPCPGTRGVRSGREGLLSP-APRSALGETAPTAQFTFRKVRNPP 537
            +  PPGA  A     E+   G  G   G  G   P  P+   G+  P        +R  P
Sbjct: 1322 KRGPPGAAGAEGRQGEKGAKGEAGA-EGPPGKTGPVGPQGPAGKPGPEG------LRGIP 1374

Query: 538  GPRG--GAMSAAGTRSPPGP 555
            GP G  G   AAG   PPGP
Sbjct: 1375 GPVGEQGLPGAAGQDGPPGP 1394



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 81/287 (28%), Positives = 100/287 (34%), Gaps = 58/287 (20%)

Query: 289  PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQ 347
            P G         PP     P   GPP   GP G P     P  P           P G  
Sbjct: 1235 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG----------PPGEP 1284

Query: 348  SLA--EGVKRDGGQ-GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT 404
              A  +GV  D G+ G P   G P  G SGE      G P        PP  R P     
Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPP--GPSGEA-----GPP-------GPPGKRGPP---- 1326

Query: 405  EGGGTGLPSKQ-RRGPSPKTELGGPQGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIG 462
              G  G   +Q  +G   +    GP G       +GP GP GP G P     R +   +G
Sbjct: 1327 --GAAGAEGRQGEKGAKGEAGAEGPPGK------TGPVGPQGPAGKPGPEGLRGIPGPVG 1378

Query: 463  RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS--GREGLLSPAPRSALG 520
               +P G+A        + PPG    L  D     PG++G +   G  GL+ P      G
Sbjct: 1379 EQGLP-GAAGQDGPPGPMGPPGL-PGLKGD-----PGSKGEKGHPGLIGLIGPP-----G 1426

Query: 521  ETAPTAQFTFRKVRNPPGPR--GGAMSAAGTRSPPGPAESARSRGPR 565
            E            +  PG +  GG    AG   PPGP      +GP+
Sbjct: 1427 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1473



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 80/291 (27%), Positives = 100/291 (34%), Gaps = 66/291 (22%)

Query: 301  PPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQ 359
            PP     P  +GP  +PGP G P     P PP       E G P G+  +      DG  
Sbjct: 1253 PPGAKGPPGDDGPKGNPGPVGFPGD---PGPPG------EPG-PAGQDGVGGDKGEDGDP 1302

Query: 360  GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSL----RTPTPGLT-EGGGTGLPSK 414
            G P   G P  G SGE      G P    +  PP +     R    G   E G  G P K
Sbjct: 1303 GQP---GPP--GPSGEA-----GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1352

Query: 415  Q----------RRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRV 464
                       + GP     + GP G  G    +G  GP    GPP          +  +
Sbjct: 1353 TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG---------LPGL 1403

Query: 465  RVPLGSALPYPARSELAPPGARDALSPDPE------RPCPGTRGVRSGREGLLSPAPRSA 518
            +   GS      + E   PG    + P  E      R  PGT+G    +     P P   
Sbjct: 1404 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1457

Query: 519  LGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPG 567
            LG   P        +  P GP+G  G+   AG +   G      S GP PG
Sbjct: 1458 LGPPGPPG------LPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP-PG 1501



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 90/342 (26%), Positives = 110/342 (32%), Gaps = 89/342 (26%)

Query: 286 ILPPAGHTLRLPPRSPPRLGRAPHFNGPPAH--------PGPGRPSTSPCPLPPSLLCLW 337
           IL  A   LR PP      GR     GP +         PGP  P     P  P+     
Sbjct: 480 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT----- 534

Query: 338 VESGTP--RGRQSLAEGVKRDGGQGLPDVEGAP-DMGSSG-EGAGLEEGSPLRRERAWPP 393
              G P  RGR         DGG+G+P   GA  D G  G  G   ++G    R    PP
Sbjct: 535 ---GKPGKRGRPGA------DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 585

Query: 394 --------------------PSLRTPTPGLTEGGGTGLPSKQRRG-----PSPKTELG-- 426
                               P    P   L   G  G P +         P PK  +G  
Sbjct: 586 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 645

Query: 427 ------GPQGSLGRASLSGPFGP-------GPQG-----------GPPSRDRRHLGVQIG 462
                 G QG+ G   L GP GP       GPQG           GPP    +    Q G
Sbjct: 646 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE--GQSG 703

Query: 463 RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLS-PAPRSALGE 521
                 G+  P   +  +  PG R     D  R   G++G   G +G           G+
Sbjct: 704 E----KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG-EKGEDGFPGFKGDMGLKGD 758

Query: 522 TAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRG 563
                Q   R    P GP+G     AG    PGP+  A  +G
Sbjct: 759 RGEVGQIGPRGEDGPEGPKG----RAGPTGDPGPSGQAGEKG 796



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 89/336 (26%), Positives = 108/336 (32%), Gaps = 75/336 (22%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGV 353
            P+ PP    +P   G     GP    GRP     P P        E G P G +      
Sbjct: 1010 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG------EKGAP-GEKGPQGPA 1062

Query: 354  KRDGGQGLPDVEG-APDMGSSGE-GAGLEEGSPLRR-------ERAWP-PPSLRTPT--P 401
             RDG QG   + G A   GS GE G   E G P ++       E   P PP L+ P   P
Sbjct: 1063 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1122

Query: 402  GLTEGGGTGLPSKQR-----------RG-------------PSPKTELG----------- 426
            G+  G G   P  Q+           RG             P P  E G           
Sbjct: 1123 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182

Query: 427  ---GPQGSLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVP--LGSALPYPARSEL 480
               GP+G  G     GP G PG  G       +    + G    P   G   P   R E 
Sbjct: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242

Query: 481  APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVR------ 534
               G   A  P   +  PG  G +     +  P      GE  P  Q      +      
Sbjct: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1302

Query: 535  ---NPPGPRG--GAMSAAGTRSPPGPAESARSRGPR 565
                PPGP G  G     G R PPG A +   +G +
Sbjct: 1303 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1338



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 71/279 (25%), Positives = 91/279 (32%), Gaps = 45/279 (16%)

Query: 301 PPRLGRAPHFNGPPAHPGPGRPSTSPCPL-PPSLLCLWVESGTPRGRQSLAEGVKRDGGQ 359
           PP         GPP   GP  P   P    PP    L    G P    ++     R GG 
Sbjct: 404 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 463

Query: 360 GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGP 419
           G    +G        +   + + + +   R  P P   T  PG   G G+     +   P
Sbjct: 464 GS---KGPTISAQEAQAQAILQQARIAL-RGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 519

Query: 420 SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
            P+    GP+G      + GP  PGP G P  R         GR     G  +P      
Sbjct: 520 GPQ----GPRG------VQGP--PGPTGKPGKR---------GRPGADGGRGMP------ 552

Query: 480 LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
              PGA+     D     PG +G R  R     P P    G      +   R +    GP
Sbjct: 553 -GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 611

Query: 540 RG-----------GAMSAAGTRSPPGPAESARSRGPRPG 567
           RG           G    AG   PPGP  +   +G  PG
Sbjct: 612 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG-EPG 649



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/213 (30%), Positives = 81/213 (38%), Gaps = 20/213 (9%)

Query: 358 GQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRR 417
           G G+P      +   +G GA  E+G         P   +  P       G  G P  Q  
Sbjct: 363 GPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQ-- 420

Query: 418 GPSPKTELGGPQGSLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPA 476
           GP+      G +G  GR  L G  G PGP G       R+ G      + P  SA    A
Sbjct: 421 GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG---DGSKGPTISAQEAQA 477

Query: 477 RSELAPPGARDALSPDPERPCPGTRGVRSGREGLLS-PAPRSALGETAPTAQFTFRKVRN 535
           ++ L    AR AL     R  PG  G+ +GR G +  P    A GE+        R V+ 
Sbjct: 478 QAILQQ--ARIAL-----RGPPGPMGL-TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 529

Query: 536 PPGPRG-----GAMSAAGTRSPPGPAESARSRG 563
           PPGP G     G   A G R  PG   +   RG
Sbjct: 530 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 562


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 94/328 (28%), Positives = 120/328 (36%), Gaps = 60/328 (18%)

Query: 285  PILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPR 344
            PI PP        P+  P L   P  +GPP HPG    S     L P      +    PR
Sbjct: 707  PIGPPG----EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPR 762

Query: 345  GRQSLAEGVK-------RDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLR 397
            G +  A+GV+         G  G P  +G  DMG  G+   + +  P   +    P    
Sbjct: 763  GVKG-ADGVRGLKGSKGEKGEDGFPGFKG--DMGLKGDRGEVGQIGPRGEDGPEGPKGRA 819

Query: 398  TPT--PGLT----EGGGTGLPS----KQRRGPSPKTEL------GGPQGSLGRASLSGPF 441
             PT  PG +    E G  G+P       R+GP   T         G +G+ G A   GP 
Sbjct: 820  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR 879

Query: 442  GP-GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALS-PDPERP--- 496
            G  GP G   SR  R    + G      G   P P   E  P G +  +  P P+ P   
Sbjct: 880  GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPKGPPGP 938

Query: 497  --------CPGTRGVRSGREGLLSP-------APRSALGETAPTAQFTFRKVRNPPGPRG 541
                     PG RG  +G +G   P        P+   GET P  +   R    PPGP G
Sbjct: 939  PGKDGLPGHPGQRG-ETGFQGKTGPPGPGGVVGPQGPTGETGPIGE---RGHPGPPGPPG 994

Query: 542  -----GAMSAAGTRSPPGPAESARSRGP 564
                 GA    G +  PGP   +   GP
Sbjct: 995  EQGLPGAAGKEGAKGDPGPQGISGKDGP 1022



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 90/331 (27%), Positives = 108/331 (32%), Gaps = 75/331 (22%)

Query: 283  GLPILP-PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVES 340
            GLP  P   G T       PP  G      GP    GP G       P PP       E 
Sbjct: 943  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG------EQ 996

Query: 341  GTPRGRQSLAEGVKRDGG-------------------QGLPDVEGAPDM--GSSGEGAGL 379
            G P       EG K D G                   +GLP  +GAP +  G   +G   
Sbjct: 997  GLPGAAGK--EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1054

Query: 380  EEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSG 439
              GSP  R  A     +  P  G     G   P+ ++  P  K    GPQG  GR  + G
Sbjct: 1055 PVGSPGERGSAGTAGPIGLP--GRPGPQGPPGPAGEKGAPGEK----GPQGPAGRDGVQG 1108

Query: 440  PFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCP 498
            P G PGP G                   P GS      + E+  PG + +     E   P
Sbjct: 1109 PVGLPGPAG-------------------PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1149

Query: 499  GTRGVRS--GREGLL----SPAPRSALGETAPTAQFTFRKVRNPPGPRG----------- 541
            G  G++   G  G+      P PR   G          R    PPGP G           
Sbjct: 1150 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1209

Query: 542  GAMSAAGTRSPPGPAESARSRGPRPGWDTPE 572
            G     G   PPGP      +GP  G D P+
Sbjct: 1210 GENGDVGPMGPPGPPGPRGPQGPN-GADGPQ 1239



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 81/277 (29%), Positives = 99/277 (35%), Gaps = 57/277 (20%)

Query: 312 GPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGA 367
           GP   PGP    G P     P P   +    E G P+G+  LA     DG  G P  EG 
Sbjct: 682 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG-PQGKPGLAGLPGADGPPGHPGKEG- 739

Query: 368 PDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT-------EGGGTGLPS------- 413
                SGE   L    P +    +P P       G+        E G  G P        
Sbjct: 740 ----QSGEKGALGPPGP-QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 794

Query: 414 KQRRGP----SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLG 469
           K  RG      P+ E  GP+G  GRA  +G  GP  Q G           + G++ VP  
Sbjct: 795 KGDRGEVGQIGPRGE-DGPEGPKGRAGPTGDPGPSGQAG-----------EKGKLGVP-- 840

Query: 470 SALP-YPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQF 528
             LP YP R    P G+            PG  G +  R     P PR   G T P    
Sbjct: 841 -GLPGYPGRQ--GPKGSTGFPG------FPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 891

Query: 529 TFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPR 565
             R     PGP+G     +G   PPGP      +GP+
Sbjct: 892 GARGPTGKPGPKG----TSGGDGPPGPPGERGPQGPQ 924



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 71/260 (27%), Positives = 87/260 (33%), Gaps = 61/260 (23%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
            GPP  PGP  P                 +  P+G       V   G +G P   G P  G
Sbjct: 1219 GPPGPPGPRGPQGPN------------GADGPQGPPGSVGSVGGVGEKGEPGEAGNP--G 1264

Query: 372  SSGE-GAGLEEGSPLRRERAWPPPSLRTPTPGLTEG--------GGTGLPSKQ----RRG 418
              GE G G  +G    +  A PP +   P      G        G  G P         G
Sbjct: 1265 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324

Query: 419  PSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARS 478
            P+ +  +GG +G  G     GP GP  + GPP                P G         
Sbjct: 1325 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG---------------PPG--------- 1360

Query: 479  ELAPPGARDALSPDPERPCPGTRGVRSGREGLLSP-APRSALGETAPTAQFTFRKVRNPP 537
            +  PPGA  A     E+   G  G   G  G   P  P+   G+  P        +R  P
Sbjct: 1361 KRGPPGAAGAEGRQGEKGAKGEAGA-EGPPGKTGPVGPQGPAGKPGPEG------LRGIP 1413

Query: 538  GPRG--GAMSAAGTRSPPGP 555
            GP G  G   AAG   PPGP
Sbjct: 1414 GPVGEQGLPGAAGQDGPPGP 1433



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 81/287 (28%), Positives = 100/287 (34%), Gaps = 58/287 (20%)

Query: 289  PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQ 347
            P G         PP     P   GPP   GP G P     P  P           P G  
Sbjct: 1274 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG----------PPGEP 1323

Query: 348  SLA--EGVKRDGGQ-GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT 404
              A  +GV  D G+ G P   G P  G SGE      G P        PP  R P     
Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPP--GPSGEA-----GPP-------GPPGKRGPP---- 1365

Query: 405  EGGGTGLPSKQ-RRGPSPKTELGGPQGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIG 462
              G  G   +Q  +G   +    GP G       +GP GP GP G P     R +   +G
Sbjct: 1366 --GAAGAEGRQGEKGAKGEAGAEGPPGK------TGPVGPQGPAGKPGPEGLRGIPGPVG 1417

Query: 463  RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS--GREGLLSPAPRSALG 520
               +P G+A        + PPG    L  D     PG++G +   G  GL+ P      G
Sbjct: 1418 EQGLP-GAAGQDGPPGPMGPPGL-PGLKGD-----PGSKGEKGHPGLIGLIGPP-----G 1465

Query: 521  ETAPTAQFTFRKVRNPPGPR--GGAMSAAGTRSPPGPAESARSRGPR 565
            E            +  PG +  GG    AG   PPGP      +GP+
Sbjct: 1466 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1512



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 80/291 (27%), Positives = 100/291 (34%), Gaps = 66/291 (22%)

Query: 301  PPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQ 359
            PP     P  +GP  +PGP G P     P PP       E G P G+  +      DG  
Sbjct: 1292 PPGAKGPPGDDGPKGNPGPVGFPGD---PGPPG------EPG-PAGQDGVGGDKGEDGDP 1341

Query: 360  GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSL----RTPTPGLT-EGGGTGLPSK 414
            G P   G P  G SGE      G P    +  PP +     R    G   E G  G P K
Sbjct: 1342 GQP---GPP--GPSGEA-----GPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1391

Query: 415  Q----------RRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRV 464
                       + GP     + GP G  G    +G  GP    GPP          +  +
Sbjct: 1392 TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG---------LPGL 1442

Query: 465  RVPLGSALPYPARSELAPPGARDALSPDPE------RPCPGTRGVRSGREGLLSPAPRSA 518
            +   GS      + E   PG    + P  E      R  PGT+G    +     P P   
Sbjct: 1443 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1496

Query: 519  LGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPG 567
            LG   P        +  P GP+G  G+   AG +   G      S GP PG
Sbjct: 1497 LGPPGPPG------LPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP-PG 1540



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 90/342 (26%), Positives = 110/342 (32%), Gaps = 89/342 (26%)

Query: 286 ILPPAGHTLRLPPRSPPRLGRAPHFNGPPAH--------PGPGRPSTSPCPLPPSLLCLW 337
           IL  A   LR PP      GR     GP +         PGP  P     P  P+     
Sbjct: 519 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT----- 573

Query: 338 VESGTP--RGRQSLAEGVKRDGGQGLPDVEGAP-DMGSSG-EGAGLEEGSPLRRERAWPP 393
              G P  RGR         DGG+G+P   GA  D G  G  G   ++G    R    PP
Sbjct: 574 ---GKPGKRGRPGA------DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 624

Query: 394 --------------------PSLRTPTPGLTEGGGTGLPSKQRRG-----PSPKTELG-- 426
                               P    P   L   G  G P +         P PK  +G  
Sbjct: 625 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 684

Query: 427 ------GPQGSLGRASLSGPFGP-------GPQG-----------GPPSRDRRHLGVQIG 462
                 G QG+ G   L GP GP       GPQG           GPP    +    Q G
Sbjct: 685 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE--GQSG 742

Query: 463 RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLS-PAPRSALGE 521
                 G+  P   +  +  PG R     D  R   G++G   G +G           G+
Sbjct: 743 E----KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG-EKGEDGFPGFKGDMGLKGD 797

Query: 522 TAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRG 563
                Q   R    P GP+G     AG    PGP+  A  +G
Sbjct: 798 RGEVGQIGPRGEDGPEGPKG----RAGPTGDPGPSGQAGEKG 835



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 89/336 (26%), Positives = 108/336 (32%), Gaps = 75/336 (22%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGV 353
            P+ PP    +P   G     GP    GRP     P P        E G P G +      
Sbjct: 1049 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG------EKGAP-GEKGPQGPA 1101

Query: 354  KRDGGQGLPDVEG-APDMGSSGE-GAGLEEGSPLRR-------ERAWP-PPSLRTPT--P 401
             RDG QG   + G A   GS GE G   E G P ++       E   P PP L+ P   P
Sbjct: 1102 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1161

Query: 402  GLTEGGGTGLPSKQR-----------RG-------------PSPKTELG----------- 426
            G+  G G   P  Q+           RG             P P  E G           
Sbjct: 1162 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221

Query: 427  ---GPQGSLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVP--LGSALPYPARSEL 480
               GP+G  G     GP G PG  G       +    + G    P   G   P   R E 
Sbjct: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281

Query: 481  APPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVR------ 534
               G   A  P   +  PG  G +     +  P      GE  P  Q      +      
Sbjct: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1341

Query: 535  ---NPPGPRG--GAMSAAGTRSPPGPAESARSRGPR 565
                PPGP G  G     G R PPG A +   +G +
Sbjct: 1342 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1377



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 71/279 (25%), Positives = 91/279 (32%), Gaps = 45/279 (16%)

Query: 301 PPRLGRAPHFNGPPAHPGPGRPSTSPCPL-PPSLLCLWVESGTPRGRQSLAEGVKRDGGQ 359
           PP         GPP   GP  P   P    PP    L    G P    ++     R GG 
Sbjct: 443 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 502

Query: 360 GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGP 419
           G    +G        +   + + + +   R  P P   T  PG   G G+     +   P
Sbjct: 503 GS---KGPTISAQEAQAQAILQQARIAL-RGPPGPMGLTGRPGPVGGPGSSGAKGESGDP 558

Query: 420 SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
            P+    GP+G      + GP  PGP G P  R         GR     G  +P      
Sbjct: 559 GPQ----GPRG------VQGP--PGPTGKPGKR---------GRPGADGGRGMP------ 591

Query: 480 LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
              PGA+     D     PG +G R  R     P P    G      +   R +    GP
Sbjct: 592 -GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGP 650

Query: 540 RG-----------GAMSAAGTRSPPGPAESARSRGPRPG 567
           RG           G    AG   PPGP  +   +G  PG
Sbjct: 651 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG-EPG 688



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/213 (30%), Positives = 81/213 (38%), Gaps = 20/213 (9%)

Query: 358 GQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRR 417
           G G+P      +   +G GA  E+G         P   +  P       G  G P  Q  
Sbjct: 402 GPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQ-- 459

Query: 418 GPSPKTELGGPQGSLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPA 476
           GP+      G +G  GR  L G  G PGP G       R+ G      + P  SA    A
Sbjct: 460 GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG---DGSKGPTISAQEAQA 516

Query: 477 RSELAPPGARDALSPDPERPCPGTRGVRSGREGLLS-PAPRSALGETAPTAQFTFRKVRN 535
           ++ L    AR AL     R  PG  G+ +GR G +  P    A GE+        R V+ 
Sbjct: 517 QAILQQ--ARIAL-----RGPPGPMGL-TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 568

Query: 536 PPGPRG-----GAMSAAGTRSPPGPAESARSRG 563
           PPGP G     G   A G R  PG   +   RG
Sbjct: 569 PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 601


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 99/311 (31%), Positives = 112/311 (36%), Gaps = 77/311 (24%)

Query: 283 GLP--ILPPAGHTLRLPP--------RSPPRLGRAPHFNGPPAHPGP------GRPSTSP 326
           GLP  + PP    LR  P        R PP         GPP  PGP      G+P    
Sbjct: 129 GLPGKVGPPGQPGLRGEPGIRGDQGLRGPP---------GPPGLPGPSGITIPGKPGAQG 179

Query: 327 CPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLR 386
            P PP         G P        G+K D G G P + GAP  G          G+P  
Sbjct: 180 VPGPPGFQGEPGPQGEPGPPGD--RGLKGDNGVGQPGLPGAPGQG----------GAP-- 225

Query: 387 RERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQ 446
                 PP L  P  GL + G  GLP      P  K E  GP G  G     G  GP   
Sbjct: 226 -----GPPGLPGPA-GLGKPGLDGLPG----APGDKGE-SGPPGVPGPRGEPGAVGP--- 271

Query: 447 GGPPSRDRRHLGVQIGRVRVPLGSALPYP-----ARSELAPPGARDALSPD----PERPC 497
            GPP  D          V VP  + LP P     A+ E    G    + P     P  P 
Sbjct: 272 KGPPGVD---------GVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPG 322

Query: 498 P-GTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPA 556
           P G RG  +G  GLL    R   GE     +   + +  PPG  G A    G R PPGP 
Sbjct: 323 PKGDRG-PAGVPGLL--GDRGEPGEDGEPGEQGPQGLGGPPGLPGSA-GLPGRRGPPGPK 378

Query: 557 ESARSRGPRPG 567
             A   GP PG
Sbjct: 379 GEAGPGGP-PG 388



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 95/299 (31%), Positives = 109/299 (36%), Gaps = 70/299 (23%)

Query: 285 PILPP----AGHTLRLP-PRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVE 339
           P+ PP     G  L +P P  P  L   P   GPP  PGP  P     P PP        
Sbjct: 51  PVGPPFREGKGQYLEMPLPLLPMDLKGEP---GPPGKPGPRGP-----PGPPGF------ 96

Query: 340 SGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPP--PSLR 397
            G P        G+ + G  G P   G P     G+      G P    +  PP  P LR
Sbjct: 97  PGKP--------GMGKPGLHGQPGPAGPPGFSRMGKA-----GPPGLPGKVGPPGQPGLR 143

Query: 398 TPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQ-----GSLGRASLSGPFG----PGPQGG 448
              PG+   G  GL     RGP     L GP      G  G   + GP G    PGPQG 
Sbjct: 144 -GEPGIR--GDQGL-----RGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGE 195

Query: 449 P-PSRDRRHLGVQ-IGRVRVP----LGSALPYPARSELAPPGARDALSPDPERPCPGTRG 502
           P P  DR   G   +G+  +P     G A   P    L  P        D     PG +G
Sbjct: 196 PGPPGDRGLKGDNGVGQPGLPGAPGQGGA---PGPPGLPGPAGLGKPGLDGLPGAPGDKG 252

Query: 503 VRSGREGLLSPAPRSALGETAPTAQFTFRKVRNP-----PGPRG--GAMSAAGTRSPPG 554
             SG  G+  P PR   G   P        V  P     PGP+G  GA    GTR PPG
Sbjct: 253 -ESGPPGV--PGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPG 308



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 89/277 (32%), Positives = 101/277 (36%), Gaps = 48/277 (17%)

Query: 312 GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
           GPP   G G P  +  P P        E GT RG   L  G    G  GLP  +G  D G
Sbjct: 273 GPPGVDGVGVPGAAGLPGPQGPSGAKGEPGT-RGPPGLI-GPTGYGMPGLPGPKG--DRG 328

Query: 372 SSG-------EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTE 424
            +G        G   E+G P  +     P  L  P PGL   G  GLP + R  P PK E
Sbjct: 329 PAGVPGLLGDRGEPGEDGEPGEQG----PQGLGGP-PGLP--GSAGLPGR-RGPPGPKGE 380

Query: 425 LGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAP-- 482
             GP G  G   + G  GP    G P       GV  G   +P     P P   +  P  
Sbjct: 381 -AGPGGPPGVPGIRGDQGPSGLAGKP-------GVP-GERGLPGAHGPPGPTGPKGEPGF 431

Query: 483 ------PGARDALSPDPERPCPGTRGVR--SGREGLLSPAPRSALGETAPTAQFTFRKVR 534
                 PG   AL    +   PG  G+R  SG  GL  PA     G   P      +   
Sbjct: 432 TGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPA-----GPIGPQGLPGLKGEP 486

Query: 535 NPPGP----RGGAMSAAGTRSPPGPAESARSRGPRPG 567
             PGP    R G    AG   PPG   S    GP PG
Sbjct: 487 GLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGP-PG 522



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 89/308 (28%), Positives = 103/308 (33%), Gaps = 49/308 (15%)

Query: 281 AAGLP-ILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWV- 338
           AAGLP    P+G       R PP L   P   G P  PGP +    P  +P  L      
Sbjct: 285 AAGLPGPQGPSGAKGEPGTRGPPGL-IGPTGYGMPGLPGP-KGDRGPAGVPGLLGDRGEP 342

Query: 339 -ESGTP--RGRQSLAEGVKRDGGQGLPDVEGAPD-MGSSGEG--------------AGLE 380
            E G P  +G Q L       G  GLP   G P   G +G G              +GL 
Sbjct: 343 GEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA 402

Query: 381 EGSPLRRERAWP----PPSLRTPT--PGLT-------------EGGGTGLPSKQR-RGPS 420
               +  ER  P    PP    P   PG T             + G  GLP +   RGPS
Sbjct: 403 GKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS 462

Query: 421 PKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRR---HLGVQIGRVRVPLGSALPYPAR 477
               L GP G +G   L G  G     GPP   R          G   VP    +  P  
Sbjct: 463 GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPP- 521

Query: 478 SELAPPGARDALSPDPERPCPGTRGVRSGREGLL---SPAPRSALGETAPTAQFTFRKVR 534
               PPG   A     E    G      G EG +      P+  LGE +  A   F  V 
Sbjct: 522 GPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVL 581

Query: 535 NPPGPRGG 542
             P P  G
Sbjct: 582 TSPFPASG 589


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 89/310 (28%), Positives = 111/310 (35%), Gaps = 62/310 (20%)

Query: 298 PRSPPRLGRA--PHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKR 355
           P  P ++G +  P   GPP   GP  P   P            E G P G   L   +  
Sbjct: 594 PGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG--------ELG-PVGSPGLPGKLGS 644

Query: 356 DGGQGLPDVEGAPDM-GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSK 414
            G  GLP + G P + G  G+   + E  P   + A              E G  GLP  
Sbjct: 645 LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGA---SGEEGEAGERGELGDIGLPGP 701

Query: 415 QRRGPSP-KTELGGPQGSLGRASLSGPFG-PGPQG--------------GPPSRD----- 453
           +    +P +  L GP+GS G   + GP G PGP+G              GPP R      
Sbjct: 702 KGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQH 761

Query: 454 ---------RRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVR 504
                    + H       ++ P   A   P R     PG      P  E   PG  G+R
Sbjct: 762 IKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR-----PGPPGPPGPPGENGFPGQMGIR 816

Query: 505 SGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARS- 561
            G  G+    P  ALG   P      +  R PPG RG  G   A G    PGPA   R+ 
Sbjct: 817 -GLPGI--KGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNG 872

Query: 562 ----RGPRPG 567
               RGP PG
Sbjct: 873 RDGERGP-PG 881



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 81/280 (28%), Positives = 92/280 (32%), Gaps = 66/280 (23%)

Query: 312 GPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGA 367
           GPP   GP    G       P  P           P+G   L     RDG  G+P  +G 
Sbjct: 508 GPPGEAGPKGDRGAEGARGIPGLPG----------PKGDTGLPGVDGRDGIPGMPGTKGE 557

Query: 368 PDMGSSGEGAGLE-----EGSPLRRERAWPPPSLRTP-TPGLTEGGGTGLPSKQRRGPSP 421
           P        AGL+      G P  +  A    S   P  PG  + G +G P +Q  GP  
Sbjct: 558 PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG--QMGNSGKPGQQ--GPPG 613

Query: 422 KTELGGPQGSLGRASLSGPFG-------------------PGPQGGPPSRDRRHLGVQIG 462
           +    GPQG  G     GP G                   PGP G P  +  R      G
Sbjct: 614 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR------G 667

Query: 463 RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSP-APRSALGE 521
            V  P G      A  E    G R  L  D   P P       G  GL  P   R   G 
Sbjct: 668 VVGEP-GPKGEQGASGEEGEAGERGELG-DIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV 725

Query: 522 TAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPA 556
             P         R PPGPRG     GA    G + PPG A
Sbjct: 726 EGP---------RGPPGPRGVQGEQGATGLPGVQGPPGRA 756



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 82/295 (27%), Positives = 101/295 (34%), Gaps = 88/295 (29%)

Query: 312 GPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAP-D 369
           GPP  PGP G P     P  P         GTP             G  GL   +G+P  
Sbjct: 299 GPPGPPGPAGEPGKPGAPGKP---------GTP-------------GADGLTGPDGSPGS 336

Query: 370 MGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQ 429
           +GS G+    E G P                      G  G P +   GP       G  
Sbjct: 337 IGSKGQKG--EPGVP----------------------GSRGFPGRGIPGPPGPPGTAGLP 372

Query: 430 GSLGRASLSGPFG-PGPQGGP----PSRDRRHLGVQIGRVRVPLGSALP-----YP---- 475
           G LGR    GP G PG +G P    P   R  +G   G    P  +A P     YP    
Sbjct: 373 GELGRV---GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCP--NACPPGRSGYPGLPG 427

Query: 476 ------ARSELAPPGARDALSPDPERPCPGTRGVRS--GREGLLSPAPRSALGETAPTAQ 527
                 A+ E+  PG +     + ++   G  G +   G +GL     R   G      +
Sbjct: 428 MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL-----RGITGIVGDKGE 482

Query: 528 FTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR-----PGWDTPEKGD 575
              R +   PGP+G  GA    G R PPG A     RG       PG   P KGD
Sbjct: 483 KGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP-KGD 536



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 76/282 (26%), Positives = 95/282 (33%), Gaps = 42/282 (14%)

Query: 301 PPRLGRA-----PHFNGPPAHPGPGRPSTS-----PCPLPPSLLCLWVESGTP-----RG 345
           P  LGR      P   GPP  PGP  P  +       PL P+  C    SG P     RG
Sbjct: 372 PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA-CPPGRSGYPGLPGMRG 430

Query: 346 RQSLAEGVKRDGGQGLPDVEGAPDMGSSGE--GAGLEEGSPLRRERAWPPPSLRTPTPGL 403
            +     +   G QG    EG  D G  GE    G      LR               GL
Sbjct: 431 HKGAKGEIGEPGRQGHKGEEG--DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGL 488

Query: 404 T-EGGGTGLPS----KQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLG 458
             E G  GLP     + +RGP  +    G +G+ G   + G  GP    G P  D     
Sbjct: 489 DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD----- 543

Query: 459 VQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSA 518
              GR  +P G         +  PPG             PG +GV   +    +P     
Sbjct: 544 ---GRDGIP-GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 599

Query: 519 LGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAES 558
           +G +    Q      + PPG  G  G     G+R   GP  S
Sbjct: 600 MGNSGKPGQ------QGPPGEVGPRGPQGLPGSRGELGPVGS 635



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 53/192 (27%), Positives = 65/192 (33%), Gaps = 53/192 (27%)

Query: 386 RRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGP-G 444
           RRE     P+  TP+    E G  G      +GP       GP G  G   + G  G  G
Sbjct: 248 RRETCHELPARITPSQTTDERGPPG-----EQGPP------GPPGPPGVPGIDGIDGDRG 296

Query: 445 PQG--GPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRG 502
           P+G  GPP                P G      A  +   PGA     PD      G++G
Sbjct: 297 PKGPPGPPG---------------PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKG 341

Query: 503 VRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-----------GAMSAAGTRS 551
            + G  G+  P  R           F  R +  PPGP G           G +   G R 
Sbjct: 342 -QKGEPGV--PGSRG----------FPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 388

Query: 552 PPGPAESARSRG 563
           PPGP      RG
Sbjct: 389 PPGPPGPPGPRG 400



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 50/178 (28%), Positives = 62/178 (34%), Gaps = 30/178 (16%)

Query: 343 PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPG 402
           PRG Q         G  GLP V+G P    + +         ++   A    SL+ P   
Sbjct: 734 PRGVQG------EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP--- 784

Query: 403 LTEGGGTGLPSKQRRG--PSPKTELG--------------GPQGSLGRASLSGPFGPGPQ 446
             + G TGLP +      P P  E G              GP G+LG     G  G   +
Sbjct: 785 --DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842

Query: 447 GGPPSRDRRHLGVQIGRVRVPLGSALPYPAR-SELAPPGARDALS-PDPERPCPGTRG 502
            GPP R    L   IG    P  ++     R  E  PPG       P P  P PG  G
Sbjct: 843 RGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGP-PGLPG 899


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 89/310 (28%), Positives = 111/310 (35%), Gaps = 62/310 (20%)

Query: 298 PRSPPRLGRA--PHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKR 355
           P  P ++G +  P   GPP   GP  P   P            E G P G   L   +  
Sbjct: 351 PGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG--------ELG-PVGSPGLPGKLGS 401

Query: 356 DGGQGLPDVEGAPDM-GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSK 414
            G  GLP + G P + G  G+   + E  P   + A              E G  GLP  
Sbjct: 402 LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGA---SGEEGEAGERGELGDIGLPGP 458

Query: 415 QRRGPSP-KTELGGPQGSLGRASLSGPFG-PGPQG--------------GPPSRD----- 453
           +    +P +  L GP+GS G   + GP G PGP+G              GPP R      
Sbjct: 459 KGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQH 518

Query: 454 ---------RRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVR 504
                    + H       ++ P   A   P R     PG      P  E   PG  G+R
Sbjct: 519 IKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR-----PGPPGPPGPPGENGFPGQMGIR 573

Query: 505 SGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARS- 561
            G  G+    P  ALG   P      +  R PPG RG  G   A G    PGPA   R+ 
Sbjct: 574 -GLPGI--KGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNG 629

Query: 562 ----RGPRPG 567
               RGP PG
Sbjct: 630 RDGERGP-PG 638



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 81/280 (28%), Positives = 92/280 (32%), Gaps = 66/280 (23%)

Query: 312 GPPAHPGP----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGA 367
           GPP   GP    G       P  P           P+G   L     RDG  G+P  +G 
Sbjct: 265 GPPGEAGPKGDRGAEGARGIPGLPG----------PKGDTGLPGVDGRDGIPGMPGTKGE 314

Query: 368 PDMGSSGEGAGLE-----EGSPLRRERAWPPPSLRTP-TPGLTEGGGTGLPSKQRRGPSP 421
           P        AGL+      G P  +  A    S   P  PG  + G +G P +Q  GP  
Sbjct: 315 PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG--QMGNSGKPGQQ--GPPG 370

Query: 422 KTELGGPQGSLGRASLSGPFG-------------------PGPQGGPPSRDRRHLGVQIG 462
           +    GPQG  G     GP G                   PGP G P  +  R      G
Sbjct: 371 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR------G 424

Query: 463 RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSP-APRSALGE 521
            V  P G      A  E    G R  L  D   P P       G  GL  P   R   G 
Sbjct: 425 VVGEP-GPKGEQGASGEEGEAGERGELG-DIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV 482

Query: 522 TAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPA 556
             P         R PPGPRG     GA    G + PPG A
Sbjct: 483 EGP---------RGPPGPRGVQGEQGATGLPGVQGPPGRA 513



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 82/295 (27%), Positives = 101/295 (34%), Gaps = 88/295 (29%)

Query: 312 GPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAP-D 369
           GPP  PGP G P     P  P         GTP             G  GL   +G+P  
Sbjct: 56  GPPGPPGPAGEPGKPGAPGKP---------GTP-------------GADGLTGPDGSPGS 93

Query: 370 MGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQ 429
           +GS G+    E G P                      G  G P +   GP       G  
Sbjct: 94  IGSKGQKG--EPGVP----------------------GSRGFPGRGIPGPPGPPGTAGLP 129

Query: 430 GSLGRASLSGPFG-PGPQGGP----PSRDRRHLGVQIGRVRVPLGSALP-----YP---- 475
           G LGR    GP G PG +G P    P   R  +G   G    P  +A P     YP    
Sbjct: 130 GELGRV---GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCP--NACPPGRSGYPGLPG 184

Query: 476 ------ARSELAPPGARDALSPDPERPCPGTRGVRS--GREGLLSPAPRSALGETAPTAQ 527
                 A+ E+  PG +     + ++   G  G +   G +GL     R   G      +
Sbjct: 185 MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL-----RGITGIVGDKGE 239

Query: 528 FTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR-----PGWDTPEKGD 575
              R +   PGP+G  GA    G R PPG A     RG       PG   P KGD
Sbjct: 240 KGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP-KGD 293



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 76/282 (26%), Positives = 95/282 (33%), Gaps = 42/282 (14%)

Query: 301 PPRLGRA-----PHFNGPPAHPGPGRPSTS-----PCPLPPSLLCLWVESGTP-----RG 345
           P  LGR      P   GPP  PGP  P  +       PL P+  C    SG P     RG
Sbjct: 129 PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA-CPPGRSGYPGLPGMRG 187

Query: 346 RQSLAEGVKRDGGQGLPDVEGAPDMGSSGE--GAGLEEGSPLRRERAWPPPSLRTPTPGL 403
            +     +   G QG    EG  D G  GE    G      LR               GL
Sbjct: 188 HKGAKGEIGEPGRQGHKGEEG--DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGL 245

Query: 404 T-EGGGTGLPS----KQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLG 458
             E G  GLP     + +RGP  +    G +G+ G   + G  GP    G P  D     
Sbjct: 246 DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD----- 300

Query: 459 VQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSA 518
              GR  +P G         +  PPG             PG +GV   +    +P     
Sbjct: 301 ---GRDGIP-GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 356

Query: 519 LGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAES 558
           +G +    Q      + PPG  G  G     G+R   GP  S
Sbjct: 357 MGNSGKPGQ------QGPPGEVGPRGPQGLPGSRGELGPVGS 392



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 50/178 (28%), Positives = 62/178 (34%), Gaps = 30/178 (16%)

Query: 343 PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPG 402
           PRG Q         G  GLP V+G P    + +         ++   A    SL+ P   
Sbjct: 491 PRGVQG------EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP--- 541

Query: 403 LTEGGGTGLPSKQRRG--PSPKTELG--------------GPQGSLGRASLSGPFGPGPQ 446
             + G TGLP +      P P  E G              GP G+LG     G  G   +
Sbjct: 542 --DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 599

Query: 447 GGPPSRDRRHLGVQIGRVRVPLGSALPYPAR-SELAPPGARDALS-PDPERPCPGTRG 502
            GPP R    L   IG    P  ++     R  E  PPG       P P  P PG  G
Sbjct: 600 RGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGP-PGLPG 656



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 45/162 (27%), Positives = 56/162 (34%), Gaps = 42/162 (25%)

Query: 416 RRGPSPKTELGGPQGSLGRASLSGPFGP-GPQG--GPPSRDRRHLGVQIGRVRVPLGSAL 472
           +RGP  +    GP G  G   + G  G  GP+G  GPP                P G   
Sbjct: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---------------PAGEPG 68

Query: 473 PYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRK 532
              A  +   PGA     PD      G++G + G  G+  P  R           F  R 
Sbjct: 69  KPGAPGKPGTPGADGLTGPDGSPGSIGSKG-QKGEPGV--PGSRG----------FPGRG 115

Query: 533 VRNPPGPRG-----------GAMSAAGTRSPPGPAESARSRG 563
           +  PPGP G           G +   G R PPGP      RG
Sbjct: 116 IPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRG 157


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 104/345 (30%), Positives = 121/345 (35%), Gaps = 63/345 (18%)

Query: 283  GLPILP-PAGHTLRLPPRSP--PRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWV 338
            G P LP P G    + P  P  P L   P   GPP  PG  G P     P  P       
Sbjct: 773  GSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG------ 826

Query: 339  ESGTP--RGRQSLA--------EGVKRDGG---QGLPDVEGAP---------------DM 370
            E G P   G Q           +G K D G   +G P  +G P               DM
Sbjct: 827  EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDM 886

Query: 371  GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT-EGGGTGLPSKQRRGPSPKTELGGPQ 429
              SG G  LE    LR  R +P P      PGL  E G  G+ S    GP+    + G +
Sbjct: 887  EGSGFGGDLEA---LRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE 943

Query: 430  GSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP-----LGSALPYPARSELAPPG 484
            G  G   L GP GP  + GPP R  +     +G    P      G+  P  AR E    G
Sbjct: 944  GPPGFPGLPGPPGPPGREGPPGRTGQK--GSLGEAGAPGHKGSKGAPGPAGARGESGLAG 1001

Query: 485  ARDALSP-----DPERPCPGTRGVRSGREGLLSP---APRSALGETAPTAQFTFR---KV 533
            A     P      P  P PG        EG   P     RSA G   P      +    V
Sbjct: 1002 APGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGV 1061

Query: 534  RNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR-PGWDTPEKGD 575
               PG +G  GA    G    PG    A  +GP+       EKGD
Sbjct: 1062 PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGD 1106



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 91/314 (28%), Positives = 102/314 (32%), Gaps = 65/314 (20%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGPGRPSTSPC---PLPPSLLCLWVESGT--PRGRQSLAEG 352
            P  P   GRA    GPP  P    P   PC   PL P+   L    G   P G       
Sbjct: 760  PGVPGPPGRA----GPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGT 815

Query: 353  VKRDGGQGLPDVEGAP-DMGSSG-------EGAGLEEGSPLRRERAWPPPSLRTPTPGLT 404
              RDG  G P  +G P D G  G        G   ++G P   ER  P P      PG +
Sbjct: 816  PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 875

Query: 405  -----------EGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG------PGPQG 447
                       EG G G   +  RGP       GP G  G     G FG      PGP G
Sbjct: 876  FRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAG 935

Query: 448  GPPSRDRRHLGVQIGRVRVPLGSALPYP--ARSELAPPGARDALSPDPERPCPGTRGVRS 505
             P        GV  GR   P    LP P        PPG         E   PG +G + 
Sbjct: 936  LP--------GVP-GREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 986

Query: 506  GREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESA----RS 561
                  +P P  A GE+          +   PGP  G     G   PPGP   A      
Sbjct: 987  ------APGPAGARGESG---------LAGAPGP-AGPPGPPGPPGPPGPGLPAGFDDME 1030

Query: 562  RGPRPGWDTPEKGD 575
                P W T    D
Sbjct: 1031 GSGGPFWSTARSAD 1044



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 90/309 (29%), Positives = 116/309 (37%), Gaps = 65/309 (21%)

Query: 299  RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSL-AEGVKRDG 357
            R    L  AP   GPP  PGP  P   P P  P+       SG P    +  A+G +  G
Sbjct: 994  RGESGLAGAPGPAGPPGPPGPPGP---PGPGLPAGFDDMEGSGGPFWSTARSADGPQ--G 1048

Query: 358  GQGLPDVEGAPDM----GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPS 413
              GLP ++G P +    G+ GE     +G P                      G  GLP 
Sbjct: 1049 PPGLPGLKGDPGVPGLPGAKGEVGA--DGVP----------------------GFPGLPG 1084

Query: 414  KQR-RGPS-PKTELG--GPQGSLGRASLSGPFGPGPQGGP------PSRDRRHLGVQIGR 463
            ++   GP  PK + G  G +G  G+  +  P  PGP G P        +D   L V  G 
Sbjct: 1085 REGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVP-GP 1143

Query: 464  VRVPLGSALPYPA--RSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGE 521
               P  +  P PA  +  L   G R +  P  E+  PG+  + S   G L PA + A GE
Sbjct: 1144 EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS--IFSPDGGALGPAQKGAKGE 1201

Query: 522  TAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLS 579
                        R PPGP G  G     G    PG       +G     +  E GD  L 
Sbjct: 1202 PG---------FRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKG-----EKGEPGDASLG 1247

Query: 580  FTMQEDVGP 588
            F M+   GP
Sbjct: 1248 FGMRGMPGP 1256



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 79/279 (28%), Positives = 97/279 (34%), Gaps = 52/279 (18%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAP-DM 370
            G P   G G+P     P PP  +    E           EG  R G  G P   G   ++
Sbjct: 1105 GDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEG--RPGFAGFPGPAGPKGNL 1162

Query: 371  GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG 430
            GS GE      GSP  +     P S+ +P     +GG  G   K  +G   +    GP G
Sbjct: 1163 GSKGE-----RGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKG---EPGFRGPPG 1209

Query: 431  SLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDAL 489
              GR    G  G PG  G P     +      G    P  ++L +  R    PPG     
Sbjct: 1210 PYGRPGYKGEIGFPGRPGRPGMNGLK------GEKGEPGDASLGFGMRGMPGPPG----- 1258

Query: 490  SPDPERPCPGT---------RGVRSGREGLLS----PAPRSALGET---APTAQFTF--- 530
             P P  P PGT            R G  GL      P P+ A GE     P  QF F   
Sbjct: 1259 PPGPPGP-PGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFL 1317

Query: 531  ---RKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRP 566
                +++   G RG A    G R  PG      S  P P
Sbjct: 1318 QLEAEMKGEKGDRGDA-GQKGERGEPGGGGFFGSSLPGP 1355



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/262 (27%), Positives = 88/262 (33%), Gaps = 61/262 (23%)

Query: 363 DVEGAPDMGSSGE-GAGLEEGSPLRRERAW---------PPPSLRTPTPG---------- 402
           D EG    G+SG+ G+GL +   L RE            PPP    P  G          
Sbjct: 653 DEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 712

Query: 403 -------LTEGGGTGLPSKQR--------RGPSPKTELGGPQGSLGRASLSGPFGPGPQG 447
                  +   G   LP            R P  + + GG +G  G   + GP G   + 
Sbjct: 713 EVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG---RA 769

Query: 448 GPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPE-RPCPGTRGVRSG 506
           GPP           G   +P    LP P  S L P G      P P+  P P  R    G
Sbjct: 770 GPP-----------GSPCLPGPPGLPCPV-SPLGPAGPALQTVPGPQGPPGPPGRDGTPG 817

Query: 507 REGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGG-AMSAAGTRSPPGPAESARSRGPR 565
           R+G   P      G+   T    F       GP+G       G R PPGP      +GP 
Sbjct: 818 RDG--EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGP------QGP- 868

Query: 566 PGWDTPEKGDHLLSFTMQEDVG 587
           PG   P      L+F   E  G
Sbjct: 869 PGPPGPSFRHDKLTFIDMEGSG 890



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 62/242 (25%), Positives = 75/242 (30%), Gaps = 27/242 (11%)

Query: 343  PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPG 402
            P GR      +   G  G P + G    G  GE      G  +R     P P      PG
Sbjct: 1210 PYGRPGYKGEIGFPGRPGRPGMNGLK--GEKGEPGDASLGFGMRGMPGPPGPPGPPGPPG 1267

Query: 403  LTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIG 462
                         R GP       GP G  G     GP  PGP G  P  D   L  ++ 
Sbjct: 1268 TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP--PGPPGQFPF-DFLQLEAEMK 1324

Query: 463  RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGET 522
              +   G A     R E    G   +  P P  P PG RG      G+  P   S  G+ 
Sbjct: 1325 GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP-PGPRGY----PGIPGPKGESIRGQP 1379

Query: 523  APTAQ-----FTFRKVRNPPGPRGG------------AMSAAGTRSPPGPAESARSRGPR 565
             P          +   + PPGP G              +S  G   PPGP     + G  
Sbjct: 1380 GPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1439

Query: 566  PG 567
             G
Sbjct: 1440 SG 1441



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 49/174 (28%), Positives = 62/174 (35%), Gaps = 18/174 (10%)

Query: 301  PPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLA--EGVKRDGG 358
            PP L       GP    G   P   P   P   L L  E    +G +  A  +G + + G
Sbjct: 1284 PPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 1343

Query: 359  QG------LPDVEGAPDMGSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGL 411
             G      LP   G P  G  G  G    +G  +R +    PP  + P PG+   G  G 
Sbjct: 1344 GGGFFGSSLPGPPGPP--GPRGYPGIPGPKGESIRGQPG--PPGPQGP-PGIGYEGRQGP 1398

Query: 412  PSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVR 465
            P     GP       GP       S+ GP GP    GPP       GV++   R
Sbjct: 1399 PGPP--GPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGASSGVRLWATR 1448



 Score = 30.8 bits (68), Expect = 5.2
 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 17/75 (22%)

Query: 261  GSSL-GCPRSGAPRMFIVYHVAAGLPILP-PAGHTLRLPP-----RSPPRLGRAPHFNGP 313
            GSSL G P    PR         G P +P P G ++R  P     + PP +G      GP
Sbjct: 1349 GSSLPGPPGPPGPR---------GYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR-QGP 1398

Query: 314  PAHPGPGRPSTSPCP 328
            P  PGP  P + P P
Sbjct: 1399 PGPPGPPGPPSFPGP 1413


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 104/345 (30%), Positives = 121/345 (35%), Gaps = 63/345 (18%)

Query: 283 GLPILP-PAGHTLRLPPRSP--PRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWV 338
           G P LP P G    + P  P  P L   P   GPP  PG  G P     P  P       
Sbjct: 358 GSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG------ 411

Query: 339 ESGTP--RGRQSLA--------EGVKRDGG---QGLPDVEGAP---------------DM 370
           E G P   G Q           +G K D G   +G P  +G P               DM
Sbjct: 412 EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471

Query: 371 GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT-EGGGTGLPSKQRRGPSPKTELGGPQ 429
             SG G  LE    LR  R +P P      PGL  E G  G+ S    GP+    + G +
Sbjct: 472 EGSGFGGDLEA---LRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE 528

Query: 430 GSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP-----LGSALPYPARSELAPPG 484
           G  G   L GP GP  + GPP R  +     +G    P      G+  P  AR E    G
Sbjct: 529 GPPGFPGLPGPPGPPGREGPPGRTGQK--GSLGEAGAPGHKGSKGAPGPAGARGESGLAG 586

Query: 485 ARDALSP-----DPERPCPGTRGVRSGREGLLSP---APRSALGETAPTAQFTFR---KV 533
           A     P      P  P PG        EG   P     RSA G   P      +    V
Sbjct: 587 APGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGV 646

Query: 534 RNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR-PGWDTPEKGD 575
              PG +G  GA    G    PG    A  +GP+       EKGD
Sbjct: 647 PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGD 691



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 91/314 (28%), Positives = 102/314 (32%), Gaps = 65/314 (20%)

Query: 298 PRSPPRLGRAPHFNGPPAHPGPGRPSTSPC---PLPPSLLCLWVESGT--PRGRQSLAEG 352
           P  P   GRA    GPP  P    P   PC   PL P+   L    G   P G       
Sbjct: 345 PGVPGPPGRA----GPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGT 400

Query: 353 VKRDGGQGLPDVEGAP-DMGSSG-------EGAGLEEGSPLRRERAWPPPSLRTPTPGLT 404
             RDG  G P  +G P D G  G        G   ++G P   ER  P P      PG +
Sbjct: 401 PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 460

Query: 405 -----------EGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG------PGPQG 447
                      EG G G   +  RGP       GP G  G     G FG      PGP G
Sbjct: 461 FRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAG 520

Query: 448 GPPSRDRRHLGVQIGRVRVPLGSALPYP--ARSELAPPGARDALSPDPERPCPGTRGVRS 505
            P        GV  GR   P    LP P        PPG         E   PG +G + 
Sbjct: 521 LP--------GVP-GREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 571

Query: 506 GREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESA----RS 561
                 +P P  A GE+          +   PGP  G     G   PPGP   A      
Sbjct: 572 ------APGPAGARGESG---------LAGAPGP-AGPPGPPGPPGPPGPGLPAGFDDME 615

Query: 562 RGPRPGWDTPEKGD 575
               P W T    D
Sbjct: 616 GSGGPFWSTARSAD 629



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 90/309 (29%), Positives = 116/309 (37%), Gaps = 65/309 (21%)

Query: 299 RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSL-AEGVKRDG 357
           R    L  AP   GPP  PGP  P   P P  P+       SG P    +  A+G +  G
Sbjct: 579 RGESGLAGAPGPAGPPGPPGPPGP---PGPGLPAGFDDMEGSGGPFWSTARSADGPQ--G 633

Query: 358 GQGLPDVEGAPDM----GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPS 413
             GLP ++G P +    G+ GE     +G P                      G  GLP 
Sbjct: 634 PPGLPGLKGDPGVPGLPGAKGEVGA--DGVP----------------------GFPGLPG 669

Query: 414 KQR-RGPS-PKTELG--GPQGSLGRASLSGPFGPGPQGGP------PSRDRRHLGVQIGR 463
           ++   GP  PK + G  G +G  G+  +  P  PGP G P        +D   L V  G 
Sbjct: 670 REGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVP-GP 728

Query: 464 VRVPLGSALPYPA--RSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGE 521
              P  +  P PA  +  L   G R +  P  E+  PG+  + S   G L PA + A GE
Sbjct: 729 EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS--IFSPDGGALGPAQKGAKGE 786

Query: 522 TAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLS 579
                       R PPGP G  G     G    PG       +G     +  E GD  L 
Sbjct: 787 PG---------FRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKG-----EKGEPGDASLG 832

Query: 580 FTMQEDVGP 588
           F M+   GP
Sbjct: 833 FGMRGMPGP 841



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 79/279 (28%), Positives = 97/279 (34%), Gaps = 52/279 (18%)

Query: 312 GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAP-DM 370
           G P   G G+P     P PP  +    E           EG  R G  G P   G   ++
Sbjct: 690 GDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEG--RPGFAGFPGPAGPKGNL 747

Query: 371 GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG 430
           GS GE      GSP  +     P S+ +P     +GG  G   K  +G   +    GP G
Sbjct: 748 GSKGE-----RGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKG---EPGFRGPPG 794

Query: 431 SLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDAL 489
             GR    G  G PG  G P     +      G    P  ++L +  R    PPG     
Sbjct: 795 PYGRPGYKGEIGFPGRPGRPGMNGLK------GEKGEPGDASLGFGMRGMPGPPG----- 843

Query: 490 SPDPERPCPGT---------RGVRSGREGLLS----PAPRSALGET---APTAQFTF--- 530
            P P  P PGT            R G  GL      P P+ A GE     P  QF F   
Sbjct: 844 PPGPPGP-PGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFL 902

Query: 531 ---RKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRP 566
               +++   G RG A    G R  PG      S  P P
Sbjct: 903 QLEAEMKGEKGDRGDA-GQKGERGEPGGGGFFGSSLPGP 940



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/262 (27%), Positives = 88/262 (33%), Gaps = 61/262 (23%)

Query: 363 DVEGAPDMGSSGE-GAGLEEGSPLRRERAW---------PPPSLRTPTPG---------- 402
           D EG    G+SG+ G+GL +   L RE            PPP    P  G          
Sbjct: 238 DEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 297

Query: 403 -------LTEGGGTGLPSKQR--------RGPSPKTELGGPQGSLGRASLSGPFGPGPQG 447
                  +   G   LP            R P  + + GG +G  G   + GP G   + 
Sbjct: 298 EVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG---RA 354

Query: 448 GPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPE-RPCPGTRGVRSG 506
           GPP           G   +P    LP P  S L P G      P P+  P P  R    G
Sbjct: 355 GPP-----------GSPCLPGPPGLPCPV-SPLGPAGPALQTVPGPQGPPGPPGRDGTPG 402

Query: 507 REGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGG-AMSAAGTRSPPGPAESARSRGPR 565
           R+G   P      G+   T    F       GP+G       G R PPGP      +GP 
Sbjct: 403 RDG--EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGP------QGP- 453

Query: 566 PGWDTPEKGDHLLSFTMQEDVG 587
           PG   P      L+F   E  G
Sbjct: 454 PGPPGPSFRHDKLTFIDMEGSG 475



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 62/242 (25%), Positives = 75/242 (30%), Gaps = 27/242 (11%)

Query: 343  PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPG 402
            P GR      +   G  G P + G    G  GE      G  +R     P P      PG
Sbjct: 795  PYGRPGYKGEIGFPGRPGRPGMNGLK--GEKGEPGDASLGFGMRGMPGPPGPPGPPGPPG 852

Query: 403  LTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIG 462
                         R GP       GP G  G     GP  PGP G  P  D   L  ++ 
Sbjct: 853  TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP--PGPPGQFPF-DFLQLEAEMK 909

Query: 463  RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGET 522
              +   G A     R E    G   +  P P  P PG RG      G+  P   S  G+ 
Sbjct: 910  GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP-PGPRGY----PGIPGPKGESIRGQP 964

Query: 523  APTAQ-----FTFRKVRNPPGPRGG------------AMSAAGTRSPPGPAESARSRGPR 565
             P          +   + PPGP G              +S  G   PPGP     + G  
Sbjct: 965  GPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1024

Query: 566  PG 567
             G
Sbjct: 1025 SG 1026



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 49/174 (28%), Positives = 62/174 (35%), Gaps = 18/174 (10%)

Query: 301  PPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLA--EGVKRDGG 358
            PP L       GP    G   P   P   P   L L  E    +G +  A  +G + + G
Sbjct: 869  PPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 928

Query: 359  QG------LPDVEGAPDMGSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGL 411
             G      LP   G P  G  G  G    +G  +R +    PP  + P PG+   G  G 
Sbjct: 929  GGGFFGSSLPGPPGPP--GPRGYPGIPGPKGESIRGQPG--PPGPQGP-PGIGYEGRQGP 983

Query: 412  PSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVR 465
            P     GP       GP       S+ GP GP    GPP       GV++   R
Sbjct: 984  PGPP--GPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGASSGVRLWATR 1033



 Score = 30.8 bits (68), Expect = 5.2
 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 17/75 (22%)

Query: 261 GSSL-GCPRSGAPRMFIVYHVAAGLPILP-PAGHTLRLPP-----RSPPRLGRAPHFNGP 313
           GSSL G P    PR         G P +P P G ++R  P     + PP +G      GP
Sbjct: 934 GSSLPGPPGPPGPR---------GYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR-QGP 983

Query: 314 PAHPGPGRPSTSPCP 328
           P  PGP  P + P P
Sbjct: 984 PGPPGPPGPPSFPGP 998


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1516

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 104/345 (30%), Positives = 121/345 (35%), Gaps = 63/345 (18%)

Query: 283 GLPILP-PAGHTLRLPPRSP--PRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWV 338
           G P LP P G    + P  P  P L   P   GPP  PG  G P     P  P       
Sbjct: 538 GSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG------ 591

Query: 339 ESGTP--RGRQSLA--------EGVKRDGG---QGLPDVEGAP---------------DM 370
           E G P   G Q           +G K D G   +G P  +G P               DM
Sbjct: 592 EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDM 651

Query: 371 GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLT-EGGGTGLPSKQRRGPSPKTELGGPQ 429
             SG G  LE    LR  R +P P      PGL  E G  G+ S    GP+    + G +
Sbjct: 652 EGSGFGGDLEA---LRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE 708

Query: 430 GSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP-----LGSALPYPARSELAPPG 484
           G  G   L GP GP  + GPP R  +     +G    P      G+  P  AR E    G
Sbjct: 709 GPPGFPGLPGPPGPPGREGPPGRTGQK--GSLGEAGAPGHKGSKGAPGPAGARGESGLAG 766

Query: 485 ARDALSP-----DPERPCPGTRGVRSGREGLLSP---APRSALGETAPTAQFTFR---KV 533
           A     P      P  P PG        EG   P     RSA G   P      +    V
Sbjct: 767 APGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGV 826

Query: 534 RNPPGPRG--GAMSAAGTRSPPGPAESARSRGPR-PGWDTPEKGD 575
              PG +G  GA    G    PG    A  +GP+       EKGD
Sbjct: 827 PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGD 871



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 91/314 (28%), Positives = 102/314 (32%), Gaps = 65/314 (20%)

Query: 298 PRSPPRLGRAPHFNGPPAHPGPGRPSTSPC---PLPPSLLCLWVESGT--PRGRQSLAEG 352
           P  P   GRA    GPP  P    P   PC   PL P+   L    G   P G       
Sbjct: 525 PGVPGPPGRA----GPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGT 580

Query: 353 VKRDGGQGLPDVEGAP-DMGSSG-------EGAGLEEGSPLRRERAWPPPSLRTPTPGLT 404
             RDG  G P  +G P D G  G        G   ++G P   ER  P P      PG +
Sbjct: 581 PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 640

Query: 405 -----------EGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG------PGPQG 447
                      EG G G   +  RGP       GP G  G     G FG      PGP G
Sbjct: 641 FRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAG 700

Query: 448 GPPSRDRRHLGVQIGRVRVPLGSALPYP--ARSELAPPGARDALSPDPERPCPGTRGVRS 505
            P        GV  GR   P    LP P        PPG         E   PG +G + 
Sbjct: 701 LP--------GVP-GREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 751

Query: 506 GREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESA----RS 561
                 +P P  A GE+          +   PGP  G     G   PPGP   A      
Sbjct: 752 ------APGPAGARGESG---------LAGAPGP-AGPPGPPGPPGPPGPGLPAGFDDME 795

Query: 562 RGPRPGWDTPEKGD 575
               P W T    D
Sbjct: 796 GSGGPFWSTARSAD 809



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 90/309 (29%), Positives = 116/309 (37%), Gaps = 65/309 (21%)

Query: 299  RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSL-AEGVKRDG 357
            R    L  AP   GPP  PGP  P   P P  P+       SG P    +  A+G +  G
Sbjct: 759  RGESGLAGAPGPAGPPGPPGPPGP---PGPGLPAGFDDMEGSGGPFWSTARSADGPQ--G 813

Query: 358  GQGLPDVEGAPDM----GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPS 413
              GLP ++G P +    G+ GE     +G P                      G  GLP 
Sbjct: 814  PPGLPGLKGDPGVPGLPGAKGEVGA--DGVP----------------------GFPGLPG 849

Query: 414  KQR-RGPS-PKTELG--GPQGSLGRASLSGPFGPGPQGGP------PSRDRRHLGVQIGR 463
            ++   GP  PK + G  G +G  G+  +  P  PGP G P        +D   L V  G 
Sbjct: 850  REGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVP-GP 908

Query: 464  VRVPLGSALPYPA--RSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGE 521
               P  +  P PA  +  L   G R +  P  E+  PG+  + S   G L PA + A GE
Sbjct: 909  EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS--IFSPDGGALGPAQKGAKGE 966

Query: 522  TAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLS 579
                        R PPGP G  G     G    PG       +G     +  E GD  L 
Sbjct: 967  PG---------FRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKG-----EKGEPGDASLG 1012

Query: 580  FTMQEDVGP 588
            F M+   GP
Sbjct: 1013 FGMRGMPGP 1021



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 79/279 (28%), Positives = 97/279 (34%), Gaps = 52/279 (18%)

Query: 312  GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAP-DM 370
            G P   G G+P     P PP  +    E           EG  R G  G P   G   ++
Sbjct: 870  GDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEG--RPGFAGFPGPAGPKGNL 927

Query: 371  GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG 430
            GS GE      GSP  +     P S+ +P     +GG  G   K  +G   +    GP G
Sbjct: 928  GSKGE-----RGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKG---EPGFRGPPG 974

Query: 431  SLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDAL 489
              GR    G  G PG  G P     +      G    P  ++L +  R    PPG     
Sbjct: 975  PYGRPGYKGEIGFPGRPGRPGMNGLK------GEKGEPGDASLGFGMRGMPGPPG----- 1023

Query: 490  SPDPERPCPGT---------RGVRSGREGLLS----PAPRSALGET---APTAQFTF--- 530
             P P  P PGT            R G  GL      P P+ A GE     P  QF F   
Sbjct: 1024 PPGPPGP-PGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFL 1082

Query: 531  ---RKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRP 566
                +++   G RG A    G R  PG      S  P P
Sbjct: 1083 QLEAEMKGEKGDRGDA-GQKGERGEPGGGGFFGSSLPGP 1120



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 71/262 (27%), Positives = 88/262 (33%), Gaps = 61/262 (23%)

Query: 363 DVEGAPDMGSSGE-GAGLEEGSPLRRERAW---------PPPSLRTPTPG---------- 402
           D EG    G+SG+ G+GL +   L RE            PPP    P  G          
Sbjct: 418 DEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 477

Query: 403 -------LTEGGGTGLPSKQR--------RGPSPKTELGGPQGSLGRASLSGPFGPGPQG 447
                  +   G   LP            R P  + + GG +G  G   + GP G   + 
Sbjct: 478 EVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG---RA 534

Query: 448 GPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPE-RPCPGTRGVRSG 506
           GPP           G   +P    LP P  S L P G      P P+  P P  R    G
Sbjct: 535 GPP-----------GSPCLPGPPGLPCPV-SPLGPAGPALQTVPGPQGPPGPPGRDGTPG 582

Query: 507 REGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGG-AMSAAGTRSPPGPAESARSRGPR 565
           R+G   P      G+   T    F       GP+G       G R PPGP      +GP 
Sbjct: 583 RDG--EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGP------QGP- 633

Query: 566 PGWDTPEKGDHLLSFTMQEDVG 587
           PG   P      L+F   E  G
Sbjct: 634 PGPPGPSFRHDKLTFIDMEGSG 655



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 62/242 (25%), Positives = 75/242 (30%), Gaps = 27/242 (11%)

Query: 343  PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPG 402
            P GR      +   G  G P + G    G  GE      G  +R     P P      PG
Sbjct: 975  PYGRPGYKGEIGFPGRPGRPGMNGLK--GEKGEPGDASLGFGMRGMPGPPGPPGPPGPPG 1032

Query: 403  LTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIG 462
                         R GP       GP G  G     GP  PGP G  P  D   L  ++ 
Sbjct: 1033 TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP--PGPPGQFPF-DFLQLEAEMK 1089

Query: 463  RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGET 522
              +   G A     R E    G   +  P P  P PG RG      G+  P   S  G+ 
Sbjct: 1090 GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP-PGPRGY----PGIPGPKGESIRGQP 1144

Query: 523  APTAQ-----FTFRKVRNPPGPRGG------------AMSAAGTRSPPGPAESARSRGPR 565
             P          +   + PPGP G              +S  G   PPGP     + G  
Sbjct: 1145 GPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1204

Query: 566  PG 567
             G
Sbjct: 1205 SG 1206



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 49/174 (28%), Positives = 62/174 (35%), Gaps = 18/174 (10%)

Query: 301  PPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLA--EGVKRDGG 358
            PP L       GP    G   P   P   P   L L  E    +G +  A  +G + + G
Sbjct: 1049 PPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 1108

Query: 359  QG------LPDVEGAPDMGSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGL 411
             G      LP   G P  G  G  G    +G  +R +    PP  + P PG+   G  G 
Sbjct: 1109 GGGFFGSSLPGPPGPP--GPRGYPGIPGPKGESIRGQPG--PPGPQGP-PGIGYEGRQGP 1163

Query: 412  PSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVR 465
            P     GP       GP       S+ GP GP    GPP       GV++   R
Sbjct: 1164 PGPP--GPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGASSGVRLWATR 1213



 Score = 30.8 bits (68), Expect = 5.2
 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 17/75 (22%)

Query: 261  GSSL-GCPRSGAPRMFIVYHVAAGLPILP-PAGHTLRLPP-----RSPPRLGRAPHFNGP 313
            GSSL G P    PR         G P +P P G ++R  P     + PP +G      GP
Sbjct: 1114 GSSLPGPPGPPGPR---------GYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR-QGP 1163

Query: 314  PAHPGPGRPSTSPCP 328
            P  PGP  P + P P
Sbjct: 1164 PGPPGPPGPPSFPGP 1178


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 92/312 (29%), Positives = 109/312 (34%), Gaps = 74/312 (23%)

Query: 298 PRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTP-----RGRQSLAE 351
           P  PP  G+A    G   HPG PGRP       P          G P     RG   L +
Sbjct: 134 PAGPP--GKA----GEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGL-D 186

Query: 352 GVKRDGGQGLPDVEGAPDMGSSGE----GAGLEEGSPLRRERAWPPPSLRT--------- 398
           G+K  G  G P V+G P  G+ GE    G     G P  R R   P              
Sbjct: 187 GLK--GQPGAPGVKGEP--GAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGP 242

Query: 399 --PTPGLTEGGGTGLPSKQRRGPSPKTELG-----------GPQGSLGRASLSGPFGPGP 445
             P   +   G  G P      P PK E+G           GP+G +G   LSGP   GP
Sbjct: 243 VGPAGPIGSAGPPGFPG----APGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPV--GP 296

Query: 446 QGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS 505
            G P +          G   V     LP P R    P GA  A                +
Sbjct: 297 PGNPGANGLTGAKGAAGLPGVAGAPGLPGP-RGIPGPVGAAGA----------------T 339

Query: 506 GREGLL-SPAPRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESA 559
           G  GL+  P P  + GE+    +      + PPGP G     G    AG+  PPGP    
Sbjct: 340 GARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLR 399

Query: 560 RSRGPR--PGWD 569
            S G R  PG D
Sbjct: 400 GSPGSRGLPGAD 411



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 80/271 (29%), Positives = 95/271 (35%), Gaps = 51/271 (18%)

Query: 312 GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
           GP    GP   S +  P  P      + S  P G          DG +G P V GA  +G
Sbjct: 586 GPRGERGPPGESGAAGPTGP------IGSRGPSGPPG------PDGNKGEPGVVGA--VG 631

Query: 372 SSGEGAGLEEGSPLRRERAWPP--------PSLRTPTPGLTEGGGTGLPSKQRRGPSPKT 423
           ++G       G P  R  A  P        P LR         G  G P      P P  
Sbjct: 632 TAGPSG--PSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVG-APGP-- 686

Query: 424 ELGGPQGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAP 482
              G  G  G A  +GP GP GP+G P  R       ++G    P G A P  A  +   
Sbjct: 687 --AGATGDRGEAGAAGPAGPAGPRGSPGERG------EVGPAG-PNGFAGPAGAAGQPGA 737

Query: 483 PGARDALSPDPERPCPGTRGV-----RSGREGLLSPAPRSALGETAPTAQFTFRKVRN-- 535
            G R A  P  E    G  G       +G  G   P P  + G+  P     F       
Sbjct: 738 KGERGAKGPKGENGVVGPTGPVGAAGPAGPNG--PPGPAGSRGDGGPPGMTGFPGAAGRT 795

Query: 536 -PPGPRGGAMSAAGTRSPPGPAESARSRGPR 565
            PPGP G     +G   PPGPA     RGPR
Sbjct: 796 GPPGPSG----ISGPPGPPGPAGKEGLRGPR 822



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 94/344 (27%), Positives = 116/344 (33%), Gaps = 94/344 (27%)

Query: 312 GPPAHPGP----------GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAE-GVK------ 354
           GP   PGP          G   T+    P  L      +G P G+    E G++      
Sbjct: 610 GPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNP 669

Query: 355 -RDGGQGLPDVEGAP-------DMGSSGE----GAGLEEGSPLRRERAWP--PPSLRTPT 400
            RDG +G P   GAP       D G +G     G     GSP  R    P  P     P 
Sbjct: 670 GRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA 729

Query: 401 PGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG-PGP-----QGGPPSRDR 454
               + G  G   +  +GP  +  + GP G +G A  +GP G PGP      GGPP    
Sbjct: 730 GAAGQPGAKG--ERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPG--M 785

Query: 455 RHLGVQIGRVRVPLGSAL------PYPARSE--------------------LAPPGARDA 488
                  GR   P  S +      P PA  E                    + PPG    
Sbjct: 786 TGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGE 845

Query: 489 LSPDPERPC---PGTRGVRS--GREGLLS----------PAPRSALGETAPTAQFTFRKV 533
             P  E      PGT G +   G  G+L           P    A+GE  P        +
Sbjct: 846 KGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLG------I 899

Query: 534 RNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGD 575
             PPG RG  GA+ + G    PG A     R   PG D P   D
Sbjct: 900 AGPPGARGPPGAVGSPGVNGAPGEA----GRDGNPGNDGPPGRD 939



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 85/276 (30%), Positives = 98/276 (35%), Gaps = 38/276 (13%)

Query: 311 NGPPAHPGP-----GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVE 365
           NG    PGP     G+    P P PP    L   SG P G           G  GLP   
Sbjct: 528 NGAQGPPGPQGVQGGKGEQGP-PGPPGFQGLPGPSG-PAGEVGKPGERGLHGEFGLPGPA 585

Query: 366 GAP-DMGSSGEGAGLEEGSPL--RRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPK 422
           G   + G  GE        P+  R     P P      PG+    GT        GPS  
Sbjct: 586 GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTA-------GPSGP 638

Query: 423 TELGGPQGSLGRASLSGPFG-PGPQG--GPPSRDRRHLGVQIGRVRVP--LGSALPYPAR 477
           + L G +G+ G     G  G PG +G  G P RD        G    P  +G+  P  A 
Sbjct: 639 SGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRD--------GARGAPGAVGAPGPAGAT 690

Query: 478 SELAPPGARDALSPDPERPCPGTRGV--RSGREGLLSPAPRS----ALGETAPTAQFTFR 531
            +    GA     P   R  PG RG    +G  G   PA  +    A GE          
Sbjct: 691 GDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGEN 750

Query: 532 KVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRPG 567
            V  P GP G A   AG   PPGPA S    GP PG
Sbjct: 751 GVVGPTGPVGAA-GPAGPNGPPGPAGSRGDGGP-PG 784



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 76/263 (28%), Positives = 86/263 (32%), Gaps = 31/263 (11%)

Query: 312 GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMG 371
           GP    GP  P+  P P            G P G         R G  G   + G P  G
Sbjct: 757 GPVGAAGPAGPNGPPGPAGSR------GDGGPPGMTGFPGAAGRTGPPGPSGISGPP--G 808

Query: 372 SSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPS-KQRRGPSPKTELGGPQG 430
             G         P  +E    P   + P     E G  G P     +GPS +    GP G
Sbjct: 809 PPG---------PAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPG 859

Query: 431 SLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP--LGSALPYPARSE---LAPPGA 485
           + G   L G   PG  G P SR  R L    G V  P  LG A P  AR     +  PG 
Sbjct: 860 TPGPQGLLG--APGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGV 917

Query: 486 RDALSPDPERPCPGTRGV--RSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-- 541
             A         PG  G   R G+ G      R   G   P           P GP G  
Sbjct: 918 NGAPGEAGRDGNPGNDGPPGRDGQPG--HKGERGYPGNIGPVGAAGAPGPHGPVGPAGKH 975

Query: 542 GAMSAAGTRSPPGPAESARSRGP 564
           G     G   P GPA +   RGP
Sbjct: 976 GNRGETGPSGPVGPAGAVGPRGP 998



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 90/356 (25%), Positives = 112/356 (31%), Gaps = 102/356 (28%)

Query: 295 RLPPRSPPRLGRAPHFNGPPAHPGP--------------------------------GRP 322
           R PP  P R G      GPP  PGP                                G P
Sbjct: 44  RGPPGPPGRDGEDGP-TGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPP 102

Query: 323 STSPCPLPPSLLCLWVESGTP--------------------------RGRQSLAEGVKRD 356
             +  P P        E G P                           GR      V   
Sbjct: 103 GAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQ 162

Query: 357 GGQGLPDVEGAPDM----GSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGL 411
           G +G P   G P      G +G +G   + G+P    +  P       TPG T  G  GL
Sbjct: 163 GARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAP--GVKGEPGAPGENGTPGQT--GARGL 218

Query: 412 PSKQRRGPSPKTELGGPQGSLGRASLSGPFGP-------GPQGGPPSRDRRHLGVQIGRV 464
           P ++ R  +P     GP G+ G     GP GP       GP G P +   +    +IG V
Sbjct: 219 PGERGRVGAP-----GPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKG---EIGAV 270

Query: 465 RVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVR--------SGREGLLSPAPR 516
               G A P   R E+  PG    + P       G  G +        +G  GL  P PR
Sbjct: 271 G-NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGL--PGPR 327

Query: 517 SALGETAPTAQFTFRKVRNPPGPRG--------GAMSAAGTRSPPGPAESARSRGP 564
              G          R +   PGP G        G   +AG + PPGP+     RGP
Sbjct: 328 GIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGP 383



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 76/297 (25%), Positives = 95/297 (31%), Gaps = 48/297 (16%)

Query: 288  PPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGR 346
            PP    +  PP  P   G+     GP    GP GR        PP       E G P G 
Sbjct: 797  PPGPSGISGPPGPPGPAGKEG-LRGPRGDQGPVGRTGEVGAVGPPGFAG---EKG-PSGE 851

Query: 347  QSLAEGVKRDGGQGL---PDVEGAP----DMGSSGEGAGLEEGSPLRRERAWPPPSLRTP 399
               A      G QGL   P + G P    + G  G    + E  PL       PP  R P
Sbjct: 852  AGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAG---PPGARGP 908

Query: 400  TPGLTEGGGTGLPSKQRR-------GPSPKTELGGPQGSLGRASLSGPFG----PGPQGG 448
               +   G  G P +  R       GP  +    G +G  G     GP G    PGP G 
Sbjct: 909  PGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHG- 967

Query: 449  PPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGRE 508
                              P+G A  +  R E  P G          R   G +G+R  + 
Sbjct: 968  ------------------PVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKG 1009

Query: 509  GLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRG 563
                  PR   G            +    G +G  G++  AG R P GP+  A   G
Sbjct: 1010 EPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDG 1066



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 91/346 (26%), Positives = 104/346 (30%), Gaps = 104/346 (30%)

Query: 308 PHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEG 366
           P   G P  PGP G P             L  E G P G +    G K + G   P    
Sbjct: 315 PGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPG-PAGSKG-ESGNKGEPGSAGPQGPP 372

Query: 367 APDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGT-GLPSKQ---------- 415
            P       G   E GS      A PP       PGL    G+ GLP             
Sbjct: 373 GPSGEEGKRGPNGEAGS------AGPPGP-----PGLRGSPGSRGLPGADGRAGVMGPPG 421

Query: 416 RRGPSPKTELGGPQGSLGR---------------------ASLSGPFG------------ 442
            RG S    + GP G  GR                     A   GP G            
Sbjct: 422 SRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIG 481

Query: 443 -------------PGPQG--GPPSR--DRRHLGVQIGR----------VRVPLGSALPYP 475
                        PGP+G  G P +  D+ H G+   R           + P G      
Sbjct: 482 PAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQG 541

Query: 476 ARSELAPPGARDALS-PDPERPC-----PGTRGVRSGREGLLSPA-------PRSALGET 522
            + E  PPG       P P  P      PG RG+  G  GL  PA       P    G  
Sbjct: 542 GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLH-GEFGLPGPAGPRGERGPPGESGAA 600

Query: 523 APTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESARSRG 563
            PT     R    PPGP G     G + A GT  P GP+     RG
Sbjct: 601 GPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERG 646



 Score = 37.0 bits (84), Expect = 0.072
 Identities = 42/149 (28%), Positives = 52/149 (34%), Gaps = 14/149 (9%)

Query: 416 RRGPS----PKTELG--GPQGSLGRASLSGPFGPGPQGGPPSRD----RRHLGVQIGRVR 465
           R+GP+    P+ E G  GP G  G    +GP GP    GPP        ++ G  +G   
Sbjct: 31  RKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP 90

Query: 466 VPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPT 525
            P+G   P         PG +    P  E   PG  G    R     P      G     
Sbjct: 91  GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKP 150

Query: 526 AQFTFRKVRNPPGPRGGAMSAAGTRSPPG 554
            +   R V  P G RG      GT   PG
Sbjct: 151 GRPGERGVVGPQGARG----FPGTPGLPG 175



 Score = 34.3 bits (77), Expect = 0.47
 Identities = 73/265 (27%), Positives = 87/265 (32%), Gaps = 46/265 (17%)

Query: 259  LLGSS--LGCPRSGAPRMFIVYHVAAGLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAH 316
            LLG+   LG P S   R       A G P   P G       R PP    +P  NG P  
Sbjct: 866  LLGAPGILGLPGSRGERGLPGVAGAVGEP--GPLGIAGPPGARGPPGAVGSPGVNGAPGE 923

Query: 317  PG-PGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRDGGQGLPDVEGAP----- 368
             G  G P       PP         G P  +G +     +   G  G P   G       
Sbjct: 924  AGRDGNPGNDG---PPG------RDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGK 974

Query: 369  --DMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPS-KQRRG----PSP 421
              + G +G    +     +       P  +R       E G  GLP  K   G    P  
Sbjct: 975  HGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGI 1034

Query: 422  KTELG--GPQGSLGRASLSGPFGPGPQGGPPSRDRR--HLGVQIGRVRVPLGSALPYPAR 477
                G  G  GS+G A   GP GP    GP  +D R  H G  +G    P G   P   +
Sbjct: 1035 AGHHGDQGAPGSVGPA---GPRGPAGPSGPAGKDGRTGHPGT-VG----PAGIRGPQGHQ 1086

Query: 478  SELAPPGARDALSPDPERPCPGTRG 502
                PPG      P P  P PG  G
Sbjct: 1087 GPAGPPG-----PPGPPGP-PGVSG 1105


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 115/400 (28%), Positives = 133/400 (33%), Gaps = 102/400 (25%)

Query: 298 PRSPPRLGRAPHFNGPPAHPG-PGRPSTS-----PCPLPPSLLCLWVESGT--------- 342
           PR P  +   P   G P  PG PG PS         P    +  L  +SG          
Sbjct: 154 PRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPG 213

Query: 343 ------PRGRQSLAEGVKRDGGQGLPDVEGAP----DMGSSG----EGAGLEEGSPLRRE 388
                 PRG Q L       G  G P   G P     +GS G     G   E+G P R  
Sbjct: 214 SVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNG 273

Query: 389 RAWPPPSLRTPTPGLTE-GGGTGLPS-KQRRG----PSPKTELGGPQGSLGRASLSGPFG 442
              P       +PG     G  GLP  K  RG      PK E+G P GS G A  +GP G
Sbjct: 274 N--PGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAP-GSKGEAGPTGPMG 330

Query: 443 P----GPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCP 498
                GP+G P  R R  LG        P G+     A      PG    L        P
Sbjct: 331 AMGPLGPRGMPGERGR--LG--------PQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFP 380

Query: 499 GTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPP 553
           G  G++ G  G     P  A G   P  Q   R    PPGP G     GA+   GT    
Sbjct: 381 GNPGMK-GEAG-----PTGARGPEGPQGQ---RGETGPPGPVGSPGLPGAIGTDGTPGAK 431

Query: 554 GPAESARSRGPRPGWDTPEKGDHLLSFTMQEDVGPLSFSSEDVCVVTEYLWEGNSDPKVG 613
           GP  S  + GP PG   P       S   Q   GP     +                   
Sbjct: 432 GPTGSPGTSGP-PGSAGPPG-----SPGPQGSTGPQGIRGQ------------------- 466

Query: 614 SSDPVIPGTKADKKTK-----------MGPMSEEDKRERR 642
             DP +PG K +   K           +GP  EE KR  R
Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPR 506



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 92/313 (29%), Positives = 113/313 (36%), Gaps = 48/313 (15%)

Query: 357 GGQGLPDVEGAP-DMGSSGE----GAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGT-G 410
           G  G+P   G P + G  GE    GA   EG   +R    PP  + +P  GL    GT G
Sbjct: 369 GPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSP--GLPGAIGTDG 426

Query: 411 LPSKQRRGPSPKTELGGPQGSLGRASLSGPFGP-GPQG--GPPSRDRRHLGVQIGRVRV- 466
            P    +GP+      GP GS G     GP G  GPQG  G P       GV   +    
Sbjct: 427 TPGA--KGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDP----GVPGFKGEAG 480

Query: 467 PLGSALPYPARSELAPPGARDALSP--DP----------ERPCPGTRGVRSGREGLLSPA 514
           P G   P+  +  + PPG      P  DP          ER  PG RG   G +GL  P 
Sbjct: 481 PKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGF-PGSDGL--PG 537

Query: 515 PRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGP--RPGWDT 570
           P+ A GE  P      +  +  PG  G  G   A G    PG        GP   PG D 
Sbjct: 538 PKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDG 597

Query: 571 PEKGDHLLSFTMQEDV----GPLSFSSEDV-------CVVTEYLWEGNSDPKVGSSDPVI 619
                  +    Q       GP   S +           V         D +VG S PV 
Sbjct: 598 RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVG 657

Query: 620 PGTKADKKTKMGP 632
           P   A ++ + GP
Sbjct: 658 PPGLAGERGEQGP 670



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 82/295 (27%), Positives = 104/295 (35%), Gaps = 66/295 (22%)

Query: 298  PRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDG 357
            P   P L       GPP     G P ++    PP           P G    A  +   G
Sbjct: 889  PNGVPGLKGGRGTQGPPG--ATGFPGSAGRVGPPG----------PAGAPGPAGPLGEPG 936

Query: 358  GQGLPDVEGAP-------DMGSSGEGAGL-EEGSPLRRERAWPPPSLRTPTPGLTEG--G 407
             +G P + G P       D G +G   G  ++G P   E   P P    P P  T G  G
Sbjct: 937  KEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDP--GEDGQPGPD-GPPGPAGTTGQRG 993

Query: 408  GTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG----PGPQGGPPSRDRRHLGVQIGR 463
              G+P +  RG      L GP G+ G+   +G  G    PGP G P S            
Sbjct: 994  IVGMPGQ--RGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG---------- 1041

Query: 464  VRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETA 523
               P+G   P         PG   A+    +R  PG  G+   +    +P P  A G+  
Sbjct: 1042 ---PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG 1098

Query: 524  PTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDH 576
                      R  PG RG  G    AG R  PGP      +GPR      +KGDH
Sbjct: 1099 Q---------RGDPGSRGPIGPPGRAGKRGLPGP------QGPR-----GDKGDH 1133



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 98/344 (28%), Positives = 123/344 (35%), Gaps = 57/344 (16%)

Query: 297 PPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGT-----PRGRQSLA 350
           PP  P   G  P  NG P   G  G P     P  P L  L    G      P+G    A
Sbjct: 259 PPGKPGEDGE-PGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVG-A 316

Query: 351 EGVKRDGGQGLPDVEGAP--DMGSSGEGAGL-EEGSPLRRERAWPPPSLRTPTPGLTEGG 407
            G K + G   P     P    G  GE   L  +G+P +R  A   P    P   L   G
Sbjct: 317 PGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRG-AHGMPGKPGPMGPLGIPG 375

Query: 408 GTGLPSKQ-RRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRV 466
            +G P     +G +  T   GP+G  G+   +GP  PGP G P       L   IG    
Sbjct: 376 SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP--PGPVGSP------GLPGAIGTDGT 427

Query: 467 PLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTA 526
           P G+  P  +     PPG+         +   G +G+R G+ G   P      GE  P  
Sbjct: 428 P-GAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR-GQPG--DPGVPGFKGEAGPKG 483

Query: 527 QFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESARSRGPR--PGWD--TPEKGDHL 577
           +     ++ P GP G     G     GT  PPGP     + G R  PG D     KG   
Sbjct: 484 EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG--- 540

Query: 578 LSFTMQEDVGPLSFSSEDVCVVTEYLWEGNSDPKVGSSDPVIPG 621
                Q + GP+                G+S PK    DP  PG
Sbjct: 541 ----AQGERGPV----------------GSSGPKGSQGDPGRPG 564



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 85/280 (30%), Positives = 100/280 (35%), Gaps = 32/280 (11%)

Query: 298 PRSPPRLGRA--PHFNGPPAHPGPGRPSTSPCPL-PPSLLCLWVESGTP--RGRQSLAEG 352
           P  P   G A  P   G P   G   PS    P+ PP L     E G P   G Q L   
Sbjct: 626 PGKPGEAGNAGVPGQRGAPGKDGEVGPSG---PVGPPGLAGERGEQGPPGPTGFQGLPGP 682

Query: 353 VKRDGGQGLPDVEGAP-DMGSSGE-GAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTG 410
               G  G P  +G P D G+ G  G   E G+P   ER  P  +      G+  G G  
Sbjct: 683 PGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP--GERGEPGITGLPGEKGMAGGHGPD 740

Query: 411 LPSKQRRGPSPKTELGGP---QGSLGRASLSGPFGP-GPQGGPPSRDRRHLGVQIGRVRV 466
            P K   GPS      GP   QG  G   ++G  GP G +GG   +         G   +
Sbjct: 741 GP-KGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799

Query: 467 P--LGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAP 524
           P  LG   P     E   PG R  + P   R  PG+RG            P  A+G   P
Sbjct: 800 PGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRG---------ENGPTGAVGFAGP 850

Query: 525 TAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGP 564
                   V+  PG  G      G    PGP   A S GP
Sbjct: 851 QGPDGQPGVKGEPGEPG----QKGDAGSPGPQGLAGSPGP 886



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 84/281 (29%), Positives = 105/281 (37%), Gaps = 66/281 (23%)

Query: 283  GLPILP-PAGHTLRLPP------RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLC 335
            G+P LP PAG   ++ P      + PP     P  NGP   PGP  P+ +          
Sbjct: 1005 GMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN---------- 1054

Query: 336  LWVESGTPRGRQSLAEGVKRDGGQ----GLPDVEGAPD----MGSSGEGAGLEEGSPLRR 387
                 GTP GR   A G + D G     GLP  +GAP     +G+ G+    + G P  R
Sbjct: 1055 ----DGTP-GRDG-AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG--QRGDPGSR 1106

Query: 388  ERAWPP--------PSLRTPTPGLTEGGGTG-LPSKQRRG-------PSPKTELGGPQGS 431
                PP        P  + P     + G  G    K  RG       P P     GP G 
Sbjct: 1107 GPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP----GPNGE 1162

Query: 432  LGRASLSGPFGP-GPQG--GPPSRDRR--HLG-VQIGRVRVPLGSALPYPARSELAPPGA 485
             G A + GPFGP GP G  GP  ++     LG +    VR  +G A P     E  PPG 
Sbjct: 1163 QGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPG- 1221

Query: 486  RDALSPDPERPCPGTRGVRSGR--EGLLSPAPRSALGETAP 524
                 P P        G   G   E +  P P     + AP
Sbjct: 1222 ----PPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAP 1258



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 97/360 (26%), Positives = 117/360 (32%), Gaps = 104/360 (28%)

Query: 285 PILPPAGHTLRLPPRSPPRLGR--------APHFNGPPAHPGPGRPSTSPCPLPPSLLCL 336
           PI PP     R P   P  +G         AP   G P   G   P  +     P     
Sbjct: 493 PIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP----- 547

Query: 337 WVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPD----MGSSGE----GAGLEEGSP---- 384
            V S  P+G Q       R G  GLP   G        G  G+    GA  E+G P    
Sbjct: 548 -VGSSGPKGSQG---DPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPG 603

Query: 385 ---LRRE---RAWPPPSLRTPTPGLT-EGGGTGLPSKQRRGPSPKTELG----------- 426
              +R +      P P   +  PG   E G  G+P  QR  P    E+G           
Sbjct: 604 SIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPG-QRGAPGKDGEVGPSGPVGPPGLA 662

Query: 427 ------GPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSEL 480
                 GP G  G   L GP GP  +GG P           G   VP             
Sbjct: 663 GERGEQGPPGPTGFQGLPGPPGPPGEGGKP-----------GDQGVP------------- 698

Query: 481 APPGARDALSPDPERPCPGTRGVRS-----GREGLL----------SPAPRSALGETAPT 525
             PGA   L P  ER  PG RG        G +G+           SP P    G+T P 
Sbjct: 699 GDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPP 758

Query: 526 AQFTF---RKVRNPPGPRGGAMSAAGTRSPPGPAESARSRG-------PRPGWDTPEKGD 575
                   R +   PGP+G      G +   G A +  +RG       P P   T EKG+
Sbjct: 759 GLQGMPGERGIAGTPGPKGD-RGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE 817



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 73/265 (27%), Positives = 86/265 (32%), Gaps = 49/265 (18%)

Query: 305 GRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDV 364
           G  P   G    PGP  P  S  P          E G P+GR         DG  G+P  
Sbjct: 119 GLVPVVTGIRGRPGPAGPPGSQGPRG--------ERG-PKGRPGPRGPQGIDGEPGVPGQ 169

Query: 365 EGAPDMGSSGEGAGLEEGS-PLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKT 423
            GAP         G +  S P   + A           GL E  G G       G     
Sbjct: 170 PGAPGPPGHPSHPGPDGLSRPFSAQMA-----------GLDEKSGLGSQVGLMPGSVGPV 218

Query: 424 ELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPP 483
              GPQG  G+   +GP GP  + G P                P+G   P  +R    PP
Sbjct: 219 GPRGPQGLQGQQGGAGPTGPPGEPGDPG---------------PMG---PIGSRGPEGPP 260

Query: 484 GARDALSPDPERPCPGTRGVRSGREGLL-SPAPRSALGETAPTAQFTFRKVRNPPGPRG- 541
           G       D E   PG  G   G  G   SP  R   G          R  +   GP+G 
Sbjct: 261 GKP---GEDGE---PGRNG-NPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGE 313

Query: 542 -GAMSAAGTRSPPGPAESARSRGPR 565
            GA  + G   P GP  +    GPR
Sbjct: 314 VGAPGSKGEAGPTGPMGAMGPLGPR 338


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 81/291 (27%), Positives = 104/291 (35%), Gaps = 85/291 (29%)

Query: 308 PHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEG 366
           P F GP   PGP G+      P PP           P+G +         G  GLP   G
Sbjct: 62  PGFPGPEGPPGPRGQKGDDGIPGPPG----------PKGIR---------GPPGLPGFPG 102

Query: 367 APDM-GSSG-EGAGLEEGSP----LRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRR-GP 419
            P + G  G +GA   +G P     + ER +P              G  G P  Q   GP
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFP--------------GSPGFPGLQGPPGP 148

Query: 420 SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
                + G  GS+  +SL GP G     GPP       G+Q     +P  + +P P    
Sbjct: 149 PGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-------GIQ----GLPGPTGIPGP---- 193

Query: 480 LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
           + PPG    + P      PG +G      GL    P+   GE           ++ PPGP
Sbjct: 194 IGPPGPPGLMGPPGPPGLPGPKG----NMGLNFQGPKGEKGEQG---------LQGPPGP 240

Query: 540 RG---------------GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGD 575
            G               G     G R PPGP       GP PG +  EKG+
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP-PGGEKGEKGE 290



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 81/290 (27%), Positives = 104/290 (35%), Gaps = 52/290 (17%)

Query: 311 NGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRDGGQGLPDVEGA 367
           +GPP  PG PG P       PP  L      G P  +G +  A      G  G+P   GA
Sbjct: 490 SGPPGQPGLPGLPG------PPGSL------GFPGQKGEKGQAGATGPKGLPGIPGAPGA 537

Query: 368 PDM-GSSGEGAGL-----------EEGSP-LRRERAWPPPSLRTPTPGLT--EGGGTGLP 412
           P   GS GE   +           E GSP        P    +   PGL   +G   G+ 
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 413 SKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP----- 467
            K  RGP     L G  G++G     GP G GP G    +  + +    G+  +P     
Sbjct: 598 FKGERGPPGNPGLPGLPGNIGP---MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD 654

Query: 468 LGSALPYPARSELAPPGARD---ALSPDPERP-CPGTRGV--RSGREGLLSPAPRSALGE 521
            G  +  P +  L     RD    L  DP  P  PG  G+    G  G+        +G 
Sbjct: 655 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI------PGIGL 708

Query: 522 TAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRPGWDTP 571
             P     F  +  PPG   G     G   PPGP      +G  PG+  P
Sbjct: 709 PGPPGPKGFPGIPGPPG-APGTPGRIGLEGPPGPPGFPGPKG-EPGFALP 756



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 100/359 (27%), Positives = 113/359 (31%), Gaps = 86/359 (23%)

Query: 283 GLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESG 341
           GLP LP     +  P   PP         G   +PG PG P     P          ++ 
Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP---------GQTI 659

Query: 342 TPRGRQSLAEGVKRDGGQGLPDVEGAPDM-------GSSGE----GAGLE---------- 380
           T  G+  L     RDG  GLP   G P         GS GE    G GL           
Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719

Query: 381 -------EGSPLRRERAWPPPSLRTPTPGLTEG-------GGTGLPS-KQRRGPSPKTEL 425
                   G+P R     PP     P P    G       G  GLP  K   GP      
Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779

Query: 426 GGPQGSLGRASLSGPFGP----GPQG-----GPPSRDRRHLGVQ--------IGRVRVPL 468
            GP G  GR  L G  GP    GP G     GPP      +GVQ         G +  P 
Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP--GIGVQGPPGPPGIPGPIGQPG 837

Query: 469 GSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS-----GREGLLSPAPRSALGETA 523
              +P   + +  PPG  D   P  ER  PG  G        G  GL  P    A G   
Sbjct: 838 LHGIP-GEKGDPGPPGL-DVPGPPGERGSPGIPGAPGPIGPPGSPGL--PGKAGASGFPG 893

Query: 524 PTAQFTFRKVRNPPGPRG-----------GAMSAAGTRSPPGPAESARSRGPRPGWDTP 571
              +        PPGP G           G     G    PGP     S+G  PG   P
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG-EPGLPGP 951



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 89/308 (28%), Positives = 102/308 (33%), Gaps = 38/308 (12%)

Query: 283  GLPILP----PAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLW 337
            GLP +P    P G+         P L   P   GPP   G PG P       PP L    
Sbjct: 970  GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTI 1029

Query: 338  VESGTPRGRQSLAEGVKRDGGQGLPDVEGAP----DMGSSG---------EGAGLEEGSP 384
             + G P G Q +       G  G P   G P    D G  G          G   E G P
Sbjct: 1030 GDMGFP-GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 385  LRRERAWPPPSLRTP-TPGL--TEG--GGTGLPS-KQRRGPSPKTELGGPQGSLGRASLS 438
                      S+  P  PGL  T G  G  GLP      GP     + GP G+ G     
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148

Query: 439  GPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCP 498
            GP G G   G P           G    P    +P PA  +   PG     +P P    P
Sbjct: 1149 GPVGGGGHPGQPGPP--------GEKGKPGQDGIPGPA-GQKGEPGQPGFGNPGPP-GLP 1198

Query: 499  GTRGVRSGREGLLS-PAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSA-AGTRSPPGPA 556
            G  G + G  GL   P      G         F  V+ PPGP G    A  G +  PGP 
Sbjct: 1199 GLSG-QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257

Query: 557  ESARSRGP 564
                  GP
Sbjct: 1258 GPPGRPGP 1265



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 87/306 (28%), Positives = 109/306 (35%), Gaps = 61/306 (19%)

Query: 283  GLPILPPAGHTLRLP-------PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPP 331
            GLP  P A     LP       P  P  +   P   G P  PGP    G P     P PP
Sbjct: 1107 GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ---PGPP 1163

Query: 332  SLLCLWVESGTPRGRQSLA--EGVKRDGGQ---GLPDVEGAPDM-GSSGEGA--GLEEGS 383
                   E G P G+  +    G K + GQ   G P   G P + G  G+G   G+    
Sbjct: 1164 G------EKGKP-GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 384  PLRRERAWPP----PSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSG 439
             L   +  P     P ++ P       G  G P     GP       GPQG  GR   +G
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPP------GPPGSPGPALEGPKGNP---GPQGPPGRPGPTG 1267

Query: 440  PFG-PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERP-- 496
              G PGP+G P       +  + G    P    LP   + +  PPG    L  +P RP  
Sbjct: 1268 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP-GLKGDQGPPG----LQGNPGRPGL 1322

Query: 497  -----CPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNP---PGPRGGAMSAAG 548
                  PG  GV  G  G+  P+     G   P  +        P   PGP G ++   G
Sbjct: 1323 NGMKGDPGLPGV-PGFPGMKGPS--GVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1379

Query: 549  TRSPPG 554
               PPG
Sbjct: 1380 DAGPPG 1385



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 82/268 (30%), Positives = 96/268 (35%), Gaps = 43/268 (16%)

Query: 298  PRSPPRL---GRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGV 353
            P  PP L   G      G P  PG PG P       PP L       G P GR  L  G+
Sbjct: 1274 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL------QGNP-GRPGL-NGM 1325

Query: 354  KRDGGQGLPDVEGAPDM-GSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGL 411
            K  G  GLP V G P M G SG  G+   EG P        PP      PGL    G  +
Sbjct: 1326 K--GDPGLPGVPGFPGMKGPSGVPGSAGPEGEP----GLIGPPG----PPGLPGPSGQSI 1375

Query: 412  PSKQRRGP-----SPKTE-LGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVR 465
              K   GP      P  + L GPQG  G    +GP G   + G P  D    G + G   
Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD--GAGGRKGDPG 1433

Query: 466  VPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSG----REGLLSPAPRSALGE 521
            +P       P    L  P   D L   P    PGT  V  G    R    + AP+   G 
Sbjct: 1434 LP-----GQPGTRGLDGPPGPDGLQGPPGP--PGTSSVAHGFLITRHSQTTDAPQCPQGT 1486

Query: 522  TAPTAQFTFRKVRNPPGPRGGAMSAAGT 549
                  F+   V+      G  +  AG+
Sbjct: 1487 LQVYEGFSLLYVQGNKRAHGQDLGTAGS 1514



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 74/284 (26%), Positives = 91/284 (32%), Gaps = 102/284 (35%)

Query: 299 RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRD 356
           R PP     P   GPP  PG  +                 E G P  RG+        +D
Sbjct: 266 RGPPG---PPGIRGPPGPPGGEKGEKG-------------EQGEPGKRGKPG------KD 303

Query: 357 GGQGLPDVEGAP-DMGSSGEGAGLEEGSPLRRERAWPP--PSLRTPTPG----LTEGGGT 409
           G  G P + G P D G  GE     +G   ++    PP  P L  P PG    + E G  
Sbjct: 304 GENGQPGIPGLPGDPGYPGEPG--RDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361

Query: 410 GLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG-PGPQG----GPPSRDRRHLGVQIGRV 464
           GLP            L G +G  G   + GP G PGP G    GPP              
Sbjct: 362 GLPG-----------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG------------- 397

Query: 465 RVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS--GREGLLSPAPRSALGET 522
                            PPG             PG RG +   G  G+  P P    G+ 
Sbjct: 398 -----------------PPGF------------PGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 523 APTAQFTFRKVRNPPGPRGGAMSAAG---TRSPPGPAESARSRG 563
                     +  PPGP G  +  +       PPGP  S   +G
Sbjct: 429 GAPG------LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKG 466



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 81/290 (27%), Positives = 99/290 (34%), Gaps = 75/290 (25%)

Query: 283  GLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGT 342
            G+ +  P G     PP  P  +G+ P  +G P   G   P     P PP       E G+
Sbjct: 817  GIGVQGPPG-----PPGIPGPIGQ-PGLHGIPGEKGDPGPPGLDVPGPPG------ERGS 864

Query: 343  PRGRQSLAEGVKRDGGQGLPDVEGAPDM-GSSGEGAGLEEGSPLRRERAWPPPSLRTP-- 399
            P G       +   G  GLP   GA    G+ GE   +  G P       PP  L  P  
Sbjct: 865  P-GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM--GPP------GPPGPLGIPGR 915

Query: 400  --TPGLTEGGGT----GLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRD 453
               PGL    G     GLP     GP+      G +GS G   L GP  PGP       D
Sbjct: 916  SGVPGLKGDDGLQGQPGLP-----GPT------GEKGSKGEPGLPGP--PGPM------D 956

Query: 454  RRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGV--RSGREGLL 511
               LG +                + E   PG      P   +  PG  G    SG+ GL 
Sbjct: 957  PNLLGSK--------------GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL- 1001

Query: 512  SPAPRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPA 556
             P P    G      Q     +  PPG +G     G     G   PPGP+
Sbjct: 1002 -PGPPGPKGNPGLPGQ---PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS 1047


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 81/291 (27%), Positives = 104/291 (35%), Gaps = 85/291 (29%)

Query: 308 PHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEG 366
           P F GP   PGP G+      P PP           P+G +         G  GLP   G
Sbjct: 62  PGFPGPEGPPGPRGQKGDDGIPGPPG----------PKGIR---------GPPGLPGFPG 102

Query: 367 APDM-GSSG-EGAGLEEGSP----LRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRR-GP 419
            P + G  G +GA   +G P     + ER +P              G  G P  Q   GP
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFP--------------GSPGFPGLQGPPGP 148

Query: 420 SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
                + G  GS+  +SL GP G     GPP       G+Q     +P  + +P P    
Sbjct: 149 PGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-------GIQ----GLPGPTGIPGP---- 193

Query: 480 LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
           + PPG    + P      PG +G      GL    P+   GE           ++ PPGP
Sbjct: 194 IGPPGPPGLMGPPGPPGLPGPKG----NMGLNFQGPKGEKGEQG---------LQGPPGP 240

Query: 540 RG---------------GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGD 575
            G               G     G R PPGP       GP PG +  EKG+
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP-PGGEKGEKGE 290



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 81/290 (27%), Positives = 104/290 (35%), Gaps = 52/290 (17%)

Query: 311 NGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRDGGQGLPDVEGA 367
           +GPP  PG PG P       PP  L      G P  +G +  A      G  G+P   GA
Sbjct: 490 SGPPGQPGLPGLPG------PPGSL------GFPGQKGEKGQAGATGPKGLPGIPGAPGA 537

Query: 368 PDM-GSSGEGAGL-----------EEGSP-LRRERAWPPPSLRTPTPGLT--EGGGTGLP 412
           P   GS GE   +           E GSP        P    +   PGL   +G   G+ 
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 413 SKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP----- 467
            K  RGP     L G  G++G     GP G GP G    +  + +    G+  +P     
Sbjct: 598 FKGERGPPGNPGLPGLPGNIGP---MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD 654

Query: 468 LGSALPYPARSELAPPGARD---ALSPDPERP-CPGTRGV--RSGREGLLSPAPRSALGE 521
            G  +  P +  L     RD    L  DP  P  PG  G+    G  G+        +G 
Sbjct: 655 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI------PGIGL 708

Query: 522 TAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRPGWDTP 571
             P     F  +  PPG   G     G   PPGP      +G  PG+  P
Sbjct: 709 PGPPGPKGFPGIPGPPG-APGTPGRIGLEGPPGPPGFPGPKG-EPGFALP 756



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 100/359 (27%), Positives = 113/359 (31%), Gaps = 86/359 (23%)

Query: 283 GLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESG 341
           GLP LP     +  P   PP         G   +PG PG P     P          ++ 
Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP---------GQTI 659

Query: 342 TPRGRQSLAEGVKRDGGQGLPDVEGAPDM-------GSSGE----GAGLE---------- 380
           T  G+  L     RDG  GLP   G P         GS GE    G GL           
Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719

Query: 381 -------EGSPLRRERAWPPPSLRTPTPGLTEG-------GGTGLPS-KQRRGPSPKTEL 425
                   G+P R     PP     P P    G       G  GLP  K   GP      
Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779

Query: 426 GGPQGSLGRASLSGPFGP----GPQG-----GPPSRDRRHLGVQ--------IGRVRVPL 468
            GP G  GR  L G  GP    GP G     GPP      +GVQ         G +  P 
Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP--GIGVQGPPGPPGIPGPIGQPG 837

Query: 469 GSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS-----GREGLLSPAPRSALGETA 523
              +P   + +  PPG  D   P  ER  PG  G        G  GL  P    A G   
Sbjct: 838 LHGIP-GEKGDPGPPGL-DVPGPPGERGSPGIPGAPGPIGPPGSPGL--PGKAGASGFPG 893

Query: 524 PTAQFTFRKVRNPPGPRG-----------GAMSAAGTRSPPGPAESARSRGPRPGWDTP 571
              +        PPGP G           G     G    PGP     S+G  PG   P
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG-EPGLPGP 951



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 91/322 (28%), Positives = 110/322 (34%), Gaps = 66/322 (20%)

Query: 283  GLPILPPAGHTLRLP--PRSPPRLGRA--PHFNGPPAHPG----PGRPSTSPCPLPPSLL 334
            GLP LP       LP  P +P   G    P   G P  PG    PG P     P PP   
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 335  CLWVESGTPR--GRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWP 392
             +    G P   G      G    G  G P  +G P        AG ++G P +     P
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG-QKGEPGQPGFGNP 1192

Query: 393  -PPSLRTPTPGLT----EGGGTGLPSKQRRGPSPKTELG--------------------- 426
             PP L    PGL+    +GG  G+P      P PK E G                     
Sbjct: 1193 GPPGL----PGLSGQKGDGGLPGIPGNPGL-PGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247

Query: 427  -------GPQGSLGRASLSGPFG-PGPQGGPPSRDRRHLGVQIGRVRVP--LGSALPYPA 476
                   GPQG  GR  L GP G PG  G    +  +    Q G   +P   G   P   
Sbjct: 1248 EGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1307

Query: 477  RSELAPPGARDALSPDPERP-CPGTRGVR--SGREGLLSPAPRSAL-GETAPTAQFTFRK 532
            +     PG  + +  DP  P  PG  G++  SG  G   P     L G   P        
Sbjct: 1308 QGNPGRPGL-NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL----- 1361

Query: 533  VRNPPGPRGGAMSAAGTRSPPG 554
                PGP G ++   G   PPG
Sbjct: 1362 ----PGPSGQSIIIKGDAGPPG 1379



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 82/268 (30%), Positives = 96/268 (35%), Gaps = 43/268 (16%)

Query: 298  PRSPPRL---GRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGV 353
            P  PP L   G      G P  PG PG P       PP L       G P GR  L  G+
Sbjct: 1268 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL------QGNP-GRPGL-NGM 1319

Query: 354  KRDGGQGLPDVEGAPDM-GSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGL 411
            K  G  GLP V G P M G SG  G+   EG P        PP      PGL    G  +
Sbjct: 1320 K--GDPGLPGVPGFPGMKGPSGVPGSAGPEGEP----GLIGPPG----PPGLPGPSGQSI 1369

Query: 412  PSKQRRGP-----SPKTE-LGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVR 465
              K   GP      P  + L GPQG  G    +GP G   + G P  D    G + G   
Sbjct: 1370 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD--GAGGRKGDPG 1427

Query: 466  VPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSG----REGLLSPAPRSALGE 521
            +P       P    L  P   D L   P    PGT  V  G    R    + AP+   G 
Sbjct: 1428 LP-----GQPGTRGLDGPPGPDGLQGPPGP--PGTSSVAHGFLITRHSQTTDAPQCPQGT 1480

Query: 522  TAPTAQFTFRKVRNPPGPRGGAMSAAGT 549
                  F+   V+      G  +  AG+
Sbjct: 1481 LQVYEGFSLLYVQGNKRAHGQDLGTAGS 1508



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 90/305 (29%), Positives = 110/305 (36%), Gaps = 49/305 (16%)

Query: 294  LRLPPRSP-PRLGRAPHFNGPPAHPGP-------GRPSTS--PCPLPPSLLCLWVESGTP 343
            L +P RS  P L       G P  PGP       G P     P P+ P+LL    E G P
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969

Query: 344  RGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGE-------GAGLEEGSPLRRERAWPPPSL 396
             G   +       G QGLP   G P  G SG+       G     G P +     PP   
Sbjct: 970  -GLPGIPGVSGPKGYQGLPGDPGQP--GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026

Query: 397  RT------PTPGLTEG--GGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGG 448
             T      P P   EG  G +G+P +      P  +  G +G  G +S+  P  PGP+G 
Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK--GDKGDPGISSIGLPGLPGPKGE 1084

Query: 449  PPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERP-CPGTRGVRSGR 507
            P            G V  P    LP         PGA+      P  P  PGT G   G 
Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLP-------GTPGAKG----QPGLPGFPGTPG-PPGP 1132

Query: 508  EGLLSPAPRSAL-GETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRP 566
            +G+  P     L GE  P           PPG +G      G    PGPA      G +P
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG----KPGQDGIPGPAGQKGEPG-QP 1187

Query: 567  GWDTP 571
            G+  P
Sbjct: 1188 GFGNP 1192



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 100/389 (25%), Positives = 123/389 (31%), Gaps = 102/389 (26%)

Query: 285 PILPPAGHTLRLPPRSP----PRLGRAPHFNGPPAHPG-------PGRPST-SPCPLPPS 332
           PI PP    L  PP  P    P+     +F GP    G       PG P   S    P  
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 333 LLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRR----- 387
           +     + G P  R          G  G P + G P      +G   E+G P +R     
Sbjct: 253 VEFQKGDQGLPGDR----------GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302

Query: 388 --ERAWP-------------------------------PPSLRTPTPG----LTEGGGTG 410
             E   P                               PP L  P PG    + E G  G
Sbjct: 303 DGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIG 362

Query: 411 LPSKQRRGPSPKTELGGPQGSLGRASLSGPFG------PGPQGGPPSR----DRRHLGVQ 460
           LP      P  K E G P G  G   L GP G      PGP G P  R    D    G+ 
Sbjct: 363 LPGL----PGEKGERGFP-GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 417

Query: 461 I-------GRVRVPLGSALPYPARSELAPPGARDALSPDPERP--CPGTRGVRSGREGLL 511
           I       G+   P     P PA   + P  + +   P P  P   PG +G++ G +G+ 
Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPP--SDEICEPGPPGPPGSPGDKGLQ-GEQGVK 474

Query: 512 SPAPRSAL-----GETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPG-PAESAR 560
                +       G + P  Q     +  PPG  G     G    AG   P G P     
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534

Query: 561 SRGPRPGWDTPEKGDHLLSFTMQEDVGPL 589
              P       E GD L    M+ D G L
Sbjct: 535 PGAPGFPGSKGEPGDILTFPGMKGDKGEL 563


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 81/291 (27%), Positives = 104/291 (35%), Gaps = 85/291 (29%)

Query: 308 PHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEG 366
           P F GP   PGP G+      P PP           P+G +         G  GLP   G
Sbjct: 62  PGFPGPEGPPGPRGQKGDDGIPGPPG----------PKGIR---------GPPGLPGFPG 102

Query: 367 APDM-GSSG-EGAGLEEGSP----LRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRR-GP 419
            P + G  G +GA   +G P     + ER +P              G  G P  Q   GP
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFP--------------GSPGFPGLQGPPGP 148

Query: 420 SPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSE 479
                + G  GS+  +SL GP G     GPP       G+Q     +P  + +P P    
Sbjct: 149 PGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-------GIQ----GLPGPTGIPGP---- 193

Query: 480 LAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 539
           + PPG    + P      PG +G      GL    P+   GE           ++ PPGP
Sbjct: 194 IGPPGPPGLMGPPGPPGLPGPKG----NMGLNFQGPKGEKGEQG---------LQGPPGP 240

Query: 540 RG---------------GAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGD 575
            G               G     G R PPGP       GP PG +  EKG+
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP-PGGEKGEKGE 290



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 81/290 (27%), Positives = 104/290 (35%), Gaps = 52/290 (17%)

Query: 311 NGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTP--RGRQSLAEGVKRDGGQGLPDVEGA 367
           +GPP  PG PG P       PP  L      G P  +G +  A      G  G+P   GA
Sbjct: 490 SGPPGQPGLPGLPG------PPGSL------GFPGQKGEKGQAGATGPKGLPGIPGAPGA 537

Query: 368 PDM-GSSGEGAGL-----------EEGSP-LRRERAWPPPSLRTPTPGLT--EGGGTGLP 412
           P   GS GE   +           E GSP        P    +   PGL   +G   G+ 
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 413 SKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVP----- 467
            K  RGP     L G  G++G     GP G GP G    +  + +    G+  +P     
Sbjct: 598 FKGERGPPGNPGLPGLPGNIGP---MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD 654

Query: 468 LGSALPYPARSELAPPGARD---ALSPDPERP-CPGTRGV--RSGREGLLSPAPRSALGE 521
            G  +  P +  L     RD    L  DP  P  PG  G+    G  G+        +G 
Sbjct: 655 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI------PGIGL 708

Query: 522 TAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRPGWDTP 571
             P     F  +  PPG   G     G   PPGP      +G  PG+  P
Sbjct: 709 PGPPGPKGFPGIPGPPG-APGTPGRIGLEGPPGPPGFPGPKG-EPGFALP 756



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 100/359 (27%), Positives = 113/359 (31%), Gaps = 86/359 (23%)

Query: 283 GLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESG 341
           GLP LP     +  P   PP         G   +PG PG P     P          ++ 
Sbjct: 609 GLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP---------GQTI 659

Query: 342 TPRGRQSLAEGVKRDGGQGLPDVEGAPDM-------GSSGE----GAGLE---------- 380
           T  G+  L     RDG  GLP   G P         GS GE    G GL           
Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719

Query: 381 -------EGSPLRRERAWPPPSLRTPTPGLTEG-------GGTGLPS-KQRRGPSPKTEL 425
                   G+P R     PP     P P    G       G  GLP  K   GP      
Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779

Query: 426 GGPQGSLGRASLSGPFGP----GPQG-----GPPSRDRRHLGVQ--------IGRVRVPL 468
            GP G  GR  L G  GP    GP G     GPP      +GVQ         G +  P 
Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP--GIGVQGPPGPPGIPGPIGQPG 837

Query: 469 GSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS-----GREGLLSPAPRSALGETA 523
              +P   + +  PPG  D   P  ER  PG  G        G  GL  P    A G   
Sbjct: 838 LHGIP-GEKGDPGPPGL-DVPGPPGERGSPGIPGAPGPIGPPGSPGL--PGKAGASGFPG 893

Query: 524 PTAQFTFRKVRNPPGPRG-----------GAMSAAGTRSPPGPAESARSRGPRPGWDTP 571
              +        PPGP G           G     G    PGP     S+G  PG   P
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG-EPGLPGP 951



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 82/268 (30%), Positives = 96/268 (35%), Gaps = 43/268 (16%)

Query: 298  PRSPPRL---GRAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGV 353
            P  PP L   G      G P  PG PG P       PP L       G P GR  L  G+
Sbjct: 1271 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL------QGNP-GRPGL-NGM 1322

Query: 354  KRDGGQGLPDVEGAPDM-GSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGL 411
            K  G  GLP V G P M G SG  G+   EG P        PP      PGL    G  +
Sbjct: 1323 K--GDPGLPGVPGFPGMKGPSGVPGSAGPEGEP----GLIGPPG----PPGLPGPSGQSI 1372

Query: 412  PSKQRRGP-----SPKTE-LGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVR 465
              K   GP      P  + L GPQG  G    +GP G   + G P  D    G + G   
Sbjct: 1373 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD--GAGGRKGDPG 1430

Query: 466  VPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSG----REGLLSPAPRSALGE 521
            +P       P    L  P   D L   P    PGT  V  G    R    + AP+   G 
Sbjct: 1431 LP-----GQPGTRGLDGPPGPDGLQGPPGP--PGTSSVAHGFLITRHSQTTDAPQCPQGT 1483

Query: 522  TAPTAQFTFRKVRNPPGPRGGAMSAAGT 549
                  F+   V+      G  +  AG+
Sbjct: 1484 LQVYEGFSLLYVQGNKRAHGQDLGTAGS 1511



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 90/305 (29%), Positives = 110/305 (36%), Gaps = 49/305 (16%)

Query: 294  LRLPPRSP-PRLGRAPHFNGPPAHPGP-------GRPSTS--PCPLPPSLLCLWVESGTP 343
            L +P RS  P L       G P  PGP       G P     P P+ P+LL    E G P
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969

Query: 344  RGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGE-------GAGLEEGSPLRRERAWPPPSL 396
             G   +       G QGLP   G P  G SG+       G     G P +     PP   
Sbjct: 970  -GLPGIPGVSGPKGYQGLPGDPGQP--GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026

Query: 397  RT------PTPGLTEG--GGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGG 448
             T      P P   EG  G +G+P +      P  +  G +G  G +S+  P  PGP+G 
Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK--GDKGDPGISSIGLPGLPGPKGE 1084

Query: 449  PPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERP-CPGTRGVRSGR 507
            P            G V  P    LP         PGA+      P  P  PGT G   G 
Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLP-------GTPGAKG----QPGLPGFPGTPG-PPGP 1132

Query: 508  EGLLSPAPRSAL-GETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRP 566
            +G+  P     L GE  P           PPG +G      G    PGPA      G +P
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG----KPGQDGIPGPAGQKGEPG-QP 1187

Query: 567  GWDTP 571
            G+  P
Sbjct: 1188 GFGNP 1192



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 100/389 (25%), Positives = 123/389 (31%), Gaps = 102/389 (26%)

Query: 285 PILPPAGHTLRLPPRSP----PRLGRAPHFNGPPAHPG-------PGRPST-SPCPLPPS 332
           PI PP    L  PP  P    P+     +F GP    G       PG P   S    P  
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 333 LLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRR----- 387
           +     + G P  R          G  G P + G P      +G   E+G P +R     
Sbjct: 253 VEFQKGDQGLPGDR----------GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302

Query: 388 --ERAWP-------------------------------PPSLRTPTPG----LTEGGGTG 410
             E   P                               PP L  P PG    + E G  G
Sbjct: 303 DGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIG 362

Query: 411 LPSKQRRGPSPKTELGGPQGSLGRASLSGPFG------PGPQGGPPSR----DRRHLGVQ 460
           LP      P  K E G P G  G   L GP G      PGP G P  R    D    G+ 
Sbjct: 363 LPGL----PGEKGERGFP-GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 417

Query: 461 I-------GRVRVPLGSALPYPARSELAPPGARDALSPDPERP--CPGTRGVRSGREGLL 511
           I       G+   P     P PA   + P  + +   P P  P   PG +G++ G +G+ 
Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPP--SDEICEPGPPGPPGSPGDKGLQ-GEQGVK 474

Query: 512 SPAPRSAL-----GETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPG-PAESAR 560
                +       G + P  Q     +  PPG  G     G    AG   P G P     
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534

Query: 561 SRGPRPGWDTPEKGDHLLSFTMQEDVGPL 589
              P       E GD L    M+ D G L
Sbjct: 535 PGAPGFPGSKGEPGDILTFPGMKGDKGEL 563



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 84/302 (27%), Positives = 104/302 (34%), Gaps = 56/302 (18%)

Query: 283  GLPILPPAGHTLRLP-------PRSPPRLGRAPHFNGPPAHPGP----GRPSTSPCPLPP 331
            GLP  P A     LP       P  P  +   P   G P  PGP    G P     P PP
Sbjct: 1107 GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ---PGPP 1163

Query: 332  SLLCLWVESGTPRGRQSLA--EGVKRDGGQ---GLPDVEGAPDM-GSSGEGA--GLEEGS 383
                   E G P G+  +    G K + GQ   G P   G P + G  G+G   G+    
Sbjct: 1164 G------EKGKP-GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 384  PLRRERAWPP----PSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSG 439
             L   +  P     P ++ P       G  G P     GP       GP G  G   L G
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPP------GPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPG 1270

Query: 440  PFG-PGPQGGPPSRDRRHLGVQIGRVRVP--LGSALPYPARSELAPPGARDALSPDPERP 496
            P G PG  G    +  +    Q G   +P   G   P   +     PG  + +  DP  P
Sbjct: 1271 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL-NGMKGDPGLP 1329

Query: 497  -CPGTRGVR--SGREGLLSPAPRSAL-GETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSP 552
              PG  G++  SG  G   P     L G   P            PGP G ++   G   P
Sbjct: 1330 GVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL---------PGPSGQSIIIKGDAGP 1380

Query: 553  PG 554
            PG
Sbjct: 1381 PG 1382


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 82/291 (28%), Positives = 98/291 (33%), Gaps = 51/291 (17%)

Query: 281 AAGLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVES 340
           AAG P  P    T  LP         AP   GPP  PG G+P        P L       
Sbjct: 268 AAGAPGQPGIPGTKGLPG--------APGIAGPPGPPGFGKPGL------PGL------- 306

Query: 341 GTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPT 400
              RG   L  G    G QG   + G P +       G +    +      P P   T  
Sbjct: 307 KGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGET-- 364

Query: 401 PGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG----PGPQGGPPSRDRRH 456
                 G  G P  +    SP ++  G  G  G+  L GP G    PGP+G P       
Sbjct: 365 ---GPAGPAGYPGAKGERGSPGSD--GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPG 419

Query: 457 LGVQIGRVRVPLGSALPYPARSELAP------PGARDALSPDPERPCPGTRGVRSGREGL 510
           L   +G    P G+        E  P      PG R  + P      PG++G   G  G 
Sbjct: 420 LPGPVG----PAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKG-DPGSPGP 474

Query: 511 LSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESA 559
             PA  +  G   PT          PPGPRG  G     G   PPGP   A
Sbjct: 475 PGPAGIATKGLNGPTGP------PGPPGPRGHSGEPGLPGPPGPPGPPGQA 519



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 90/317 (28%), Positives = 110/317 (34%), Gaps = 58/317 (18%)

Query: 289 PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGT------ 342
           P GH     P   P  G +P   G P  PGP  PS    P  P L     E G       
Sbjct: 70  PRGHPGPSGPPGKPGYG-SPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGD 128

Query: 343 --------PR-----------------GRQSLAEGVKRDGGQGLPDVEGAPDM-GSSGEG 376
                   PR                 G+          G +G P  +GAP + G +G+ 
Sbjct: 129 VGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQK 188

Query: 377 AGLEEGSPLR-RERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRA 435
             +  G+P R  ER  P P  + PT      G +G P   +RG +      G +G  G  
Sbjct: 189 GEMGYGAPGRPGERGLPGP--QGPT------GPSGPPGVGKRGENGVPGQPGIKGDRGFP 240

Query: 436 SLSGPFG-PGPQGGPPSRDRRHLGV-----QIGRVRVPLGSALPYPARSELAPPGARDAL 489
              GP G PGPQG P  R    +G        G+  +P    LP  A     PPG     
Sbjct: 241 GEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP-GAPGIAGPPGPPGFG 299

Query: 490 SPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAA 547
            P      PG +G R G  GL  P    A GE  P        +  PPG  G  G     
Sbjct: 300 KPG----LPGLKGER-GPAGL--PGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIP 352

Query: 548 GTRSPPGPAESARSRGP 564
           G+   PGP       GP
Sbjct: 353 GSHGLPGPKGETGPAGP 369



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 83/306 (27%), Positives = 100/306 (32%), Gaps = 60/306 (19%)

Query: 285 PILPPAGHTLRLPP--RSPPRLGRAPHFNGPPAHPG-------PGRPSTSPCPLPPSLLC 335
           PI PP       PP  R P  +G+ P   G P  PG       PG P  +  P PP    
Sbjct: 245 PIGPPGPQG---PPGERGPEGIGK-PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG--- 297

Query: 336 LWVESGTP-----RGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERA 390
            + + G P     RG   L  G    G QG   + G P +       G +    +     
Sbjct: 298 -FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHG 356

Query: 391 WPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFG----PGPQ 446
            P P   T        G  G P  +    SP ++  G  G  G+  L GP G    PGP+
Sbjct: 357 LPGPKGETGP-----AGPAGYPGAKGERGSPGSD--GKPGYPGKPGLDGPKGNPGLPGPK 409

Query: 447 GGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSG 506
           G P              V  P G   P         PG      P      PGTRG   G
Sbjct: 410 GDPG-------------VGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGP-IG 455

Query: 507 REGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAA-GTRSPPGPAESARSRGPR 565
             G+  P    + G+              PPGP G A     G   PPGP    R     
Sbjct: 456 PPGI--PGFPGSKGDPGSPG---------PPGPAGIATKGLNGPTGPPGP-PGPRGHSGE 503

Query: 566 PGWDTP 571
           PG   P
Sbjct: 504 PGLPGP 509



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 71/240 (29%), Positives = 87/240 (36%), Gaps = 54/240 (22%)

Query: 350 AEGVKRDGGQGLPDVEGAPDM----GSSGEGAGLEEGSP-LRRERAWPPPSLRTPTPGLT 404
           ++G+   G QG P   G        G SG       GSP L+ E   P P    P P   
Sbjct: 50  SKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGP----PGPSAV 105

Query: 405 -EGGGTGLPSKQ-RRGPSPKTELGGPQGSLGRASLSGPFG-PGPQGGPPSRDRRHLGVQI 461
            + G  GLP K   RGP       GP+G +G A L GP G PGP G P            
Sbjct: 106 GKPGVPGLPGKPGERGPY------GPKGDVGPAGLPGPRGPPGPPGIPG----------- 148

Query: 462 GRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGV-------------RSGRE 508
                P G ++P     +  P GA        E+  PG  G+             R G  
Sbjct: 149 -----PAGISVP-GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGER 202

Query: 509 GLLSPAPRSALGETAP--TAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPAESARSRGP 564
           GL  P P+   G + P    +     V   PG +G  G     G   PPGP      RGP
Sbjct: 203 GL--PGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGP 260


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 77/262 (29%), Positives = 99/262 (37%), Gaps = 50/262 (19%)

Query: 299 RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGG 358
           + PP +   P   GP   PG G+P  +  P P            P G+          G 
Sbjct: 254 KGPPGMHGPP---GPVGLPGVGKPGVTGFPGPQG----------PLGKPGAPGEPGPQGP 300

Query: 359 QGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRG 418
            G+P V+G P  G  G G   ++G P   +  +P        PGL   G  GLP   + G
Sbjct: 301 IGVPGVQGPP--GIPGIGKPGQDGIP--GQPGFPGGKGEQGLPGLP--GPPGLPGIGKPG 354

Query: 419 -PSPKTE--LGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYP 475
            P PK +  +GG  G+LG     GP G    GGPP           G   +P    +P P
Sbjct: 355 FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPP-----------GEPGLP---GIPGP 400

Query: 476 ARSELAPPGARDALSPDPERPCPGTRGV--RSGREGLLS-PAPRSALGETAPTAQFTFRK 532
               + PPGA     P  E    G +G     G  GL   P     LGE  P      R 
Sbjct: 401 ----MGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPG---MRG 453

Query: 533 VRNPPGPRGGAMSAAGTRSPPG 554
           +  P GP+G     AG +  PG
Sbjct: 454 LPGPIGPKG----EAGQKGVPG 471



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 90/322 (27%), Positives = 111/322 (34%), Gaps = 51/322 (15%)

Query: 283 GLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESG 341
           G P LP  G      P+    +G  P   GP    GP G P     P  P L  +    G
Sbjct: 343 GPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 402

Query: 342 TPRGRQSLAEGVKRDGG----QGLPDVEGAPDM-GSSGEGAGLEEGSPLRRERAWPPP-- 394
            P        G K +GG    QG P  +G P + G  G+   L E  P    R  P P  
Sbjct: 403 PPGAIGF--PGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGM-RGLPGPIG 459

Query: 395 ----SLRTPTPGLT-------EGGGTGLPSKQR-RGPSPKTELGGPQGSLGRASLSGPFG 442
               + +   PGL          G  G+P  Q  +GP     +GGP G +G   + GP G
Sbjct: 460 PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKG 519

Query: 443 ----PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCP 498
               PGP G P                   G   P  A     PPG   AL P  +   P
Sbjct: 520 EPGLPGPPGFP-------------------GIGKPGVAGLH-GPPGKPGALGPQGQPGLP 559

Query: 499 GTRGVRS--GREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPA 556
           G  G     G   ++ P P    GE  P        V+ PP   G      G  +   PA
Sbjct: 560 GPPGPPGPPGPPAVMPPTP-PPQGEYLPDMGLGIDGVK-PPHAYGAKKGKNGGPAYEMPA 617

Query: 557 ESARSRGPRPGWDTPEKGDHLL 578
            +A    P P    P K + LL
Sbjct: 618 FTAELTAPFPPVGAPVKFNKLL 639



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 65/248 (26%), Positives = 84/248 (33%), Gaps = 62/248 (25%)

Query: 312 GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPD-M 370
           GP   PGP  P     P PP L                        G G+P ++G P   
Sbjct: 121 GPRGEPGPRGP-----PGPPGL-----------------------PGHGIPGIKGKPGPQ 152

Query: 371 GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG 430
           G  G G     G P  +  A   P  +       E G  G+P  Q           GP G
Sbjct: 153 GYPGVGKPGMPGMP-GKPGAMGMPGAKGEIGQKGEIGPMGIPGPQ-----------GPPG 200

Query: 431 SLGRASLSGPFGPGPQGGP-PSRDRRHLGVQIGR-VRVPLGSALPYPARSELAPPGARDA 488
             G   +  P GPG  G P P  DR   G+   + +R P G             PGA   
Sbjct: 201 PHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGD-------KGFGMPGAPGV 253

Query: 489 LSPDPERPCPGTRGVRS-GREGLLS-PAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSA 546
             P      PG  G+   G+ G+   P P+  LG+     +         PGP+ G +  
Sbjct: 254 KGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGE---------PGPQ-GPIGV 303

Query: 547 AGTRSPPG 554
            G + PPG
Sbjct: 304 PGVQGPPG 311



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 43/155 (27%), Positives = 60/155 (38%), Gaps = 12/155 (7%)

Query: 408 GTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGV--QIGRVR 465
           G  +P    RG        GP+G  G   L G   PG +G P  +    +G     G   
Sbjct: 108 GKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPG 167

Query: 466 VPLGSALPYPARSELAPPGARDALS-PDPERPCPGTRGV----RSGREGLLSPAPRSALG 520
            P    +P  A+ E+   G    +  P P+ P PG  G+    + G  GL  P      G
Sbjct: 168 KPGAMGMP-GAKGEIGQKGEIGPMGIPGPQGP-PGPHGLPGIGKPGGPGL--PGQPGPKG 223

Query: 521 ETAPTAQFTFRKVRNPPGPRG-GAMSAAGTRSPPG 554
           +  P      + +R P G +G G   A G + PPG
Sbjct: 224 DRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPG 258


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 77/262 (29%), Positives = 99/262 (37%), Gaps = 50/262 (19%)

Query: 299 RSPPRLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGG 358
           + PP +   P   GP   PG G+P  +  P P            P G+          G 
Sbjct: 254 KGPPGMHGPP---GPVGLPGVGKPGVTGFPGPQG----------PLGKPGAPGEPGPQGP 300

Query: 359 QGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRG 418
            G+P V+G P  G  G G   ++G P   +  +P        PGL   G  GLP   + G
Sbjct: 301 IGVPGVQGPP--GIPGIGKPGQDGIP--GQPGFPGGKGEQGLPGLP--GPPGLPGIGKPG 354

Query: 419 -PSPKTE--LGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYP 475
            P PK +  +GG  G+LG     GP G    GGPP           G   +P    +P P
Sbjct: 355 FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPP-----------GEPGLP---GIPGP 400

Query: 476 ARSELAPPGARDALSPDPERPCPGTRGV--RSGREGLLS-PAPRSALGETAPTAQFTFRK 532
               + PPGA     P  E    G +G     G  GL   P     LGE  P      R 
Sbjct: 401 ----MGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPG---MRG 453

Query: 533 VRNPPGPRGGAMSAAGTRSPPG 554
           +  P GP+G     AG +  PG
Sbjct: 454 LPGPIGPKG----EAGQKGVPG 471



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 90/322 (27%), Positives = 111/322 (34%), Gaps = 51/322 (15%)

Query: 283 GLPILPPAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESG 341
           G P LP  G      P+    +G  P   GP    GP G P     P  P L  +    G
Sbjct: 343 GPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 402

Query: 342 TPRGRQSLAEGVKRDGG----QGLPDVEGAPDM-GSSGEGAGLEEGSPLRRERAWPPP-- 394
            P        G K +GG    QG P  +G P + G  G+   L E  P    R  P P  
Sbjct: 403 PPGAIGF--PGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGM-RGLPGPIG 459

Query: 395 ----SLRTPTPGLT-------EGGGTGLPSKQR-RGPSPKTELGGPQGSLGRASLSGPFG 442
               + +   PGL          G  G+P  Q  +GP     +GGP G +G   + GP G
Sbjct: 460 PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKG 519

Query: 443 ----PGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCP 498
               PGP G P                   G   P  A     PPG   AL P  +   P
Sbjct: 520 EPGLPGPPGFP-------------------GIGKPGVAGLH-GPPGKPGALGPQGQPGLP 559

Query: 499 GTRGVRS--GREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSAAGTRSPPGPA 556
           G  G     G   ++ P P    GE  P        V+ PP   G      G  +   PA
Sbjct: 560 GPPGPPGPPGPPAVMPPTP-PPQGEYLPDMGLGIDGVK-PPHAYGAKKGKNGGPAYEMPA 617

Query: 557 ESARSRGPRPGWDTPEKGDHLL 578
            +A    P P    P K + LL
Sbjct: 618 FTAELTAPFPPVGAPVKFNKLL 639



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 65/248 (26%), Positives = 84/248 (33%), Gaps = 62/248 (25%)

Query: 312 GPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPD-M 370
           GP   PGP  P     P PP L                        G G+P ++G P   
Sbjct: 121 GPRGEPGPRGP-----PGPPGL-----------------------PGHGIPGIKGKPGPQ 152

Query: 371 GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQG 430
           G  G G     G P  +  A   P  +       E G  G+P  Q           GP G
Sbjct: 153 GYPGVGKPGMPGMP-GKPGAMGMPGAKGEIGQKGEIGPMGIPGPQ-----------GPPG 200

Query: 431 SLGRASLSGPFGPGPQGGP-PSRDRRHLGVQIGR-VRVPLGSALPYPARSELAPPGARDA 488
             G   +  P GPG  G P P  DR   G+   + +R P G             PGA   
Sbjct: 201 PHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGD-------KGFGMPGAPGV 253

Query: 489 LSPDPERPCPGTRGVRS-GREGLLS-PAPRSALGETAPTAQFTFRKVRNPPGPRGGAMSA 546
             P      PG  G+   G+ G+   P P+  LG+     +         PGP+ G +  
Sbjct: 254 KGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGE---------PGPQ-GPIGV 303

Query: 547 AGTRSPPG 554
            G + PPG
Sbjct: 304 PGVQGPPG 311



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 43/155 (27%), Positives = 60/155 (38%), Gaps = 12/155 (7%)

Query: 408 GTGLPSKQRRGPSPKTELGGPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGV--QIGRVR 465
           G  +P    RG        GP+G  G   L G   PG +G P  +    +G     G   
Sbjct: 108 GKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPG 167

Query: 466 VPLGSALPYPARSELAPPGARDALS-PDPERPCPGTRGV----RSGREGLLSPAPRSALG 520
            P    +P  A+ E+   G    +  P P+ P PG  G+    + G  GL  P      G
Sbjct: 168 KPGAMGMP-GAKGEIGQKGEIGPMGIPGPQGP-PGPHGLPGIGKPGGPGL--PGQPGPKG 223

Query: 521 ETAPTAQFTFRKVRNPPGPRG-GAMSAAGTRSPPG 554
           +  P      + +R P G +G G   A G + PPG
Sbjct: 224 DRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPG 258


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 105/357 (29%), Positives = 126/357 (35%), Gaps = 89/357 (24%)

Query: 283  GLPILP----PAGHTLRLPPRSPPRLGRAPHFNGPPAHPGP----------------GRP 322
            G+P LP    P GH     P         P   GPP +PGP                G  
Sbjct: 671  GIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEK 730

Query: 323  STSPCPLPPSLLCLWVESGT-----PRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGA 377
                 P     + L  + G      PRG     EG K   GQ     EG P  GS+GE  
Sbjct: 731  GEDGFPGFKGDVGLKGDQGKPGAPGPRGEDG-PEGPKGQAGQA--GEEGPP--GSAGEKG 785

Query: 378  GL-EEGSPLRRERAWPPPSLRTPTP-----GLTEGGGTGLP----------SKQRRG--- 418
             L   G P    R  P  S+  P P        + G TG P          S+  RG   
Sbjct: 786  KLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPG 845

Query: 419  ----PSPKTELG-----GPQGSLGRASLSGPFG-PGPQGGPPSR----------DRRHLG 458
                P PK ++G     G  G  G   L GP G PGP+G P  +           R  LG
Sbjct: 846  ATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELG 905

Query: 459  VQIGRVRV--PLGSALPYPARSELAPPGARDALSPDPERPCPGTRGV--RSGREGLLSP- 513
             Q G+     P G   P     E+ P G R    P P  P PG +G+    GREG     
Sbjct: 906  FQ-GQTGPPGPAGVLGPQGKTGEVGPLGERG--PPGPPGP-PGEQGLPGLEGREGAKGEL 961

Query: 514  APRSALGETAPTAQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESARSRGPR 565
             P   LG+  P        +R  PGP+G     G     G + PPGP  +  S G R
Sbjct: 962  GPPGPLGKEGPAG------LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGER 1012



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 89/297 (29%), Positives = 101/297 (34%), Gaps = 73/297 (24%)

Query: 308  PHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQGLPDVEG 366
            P   GP  HPGP G         PP L     + G     +     +   G QGLP   G
Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGV----RGFVGVIGPPGLQGLPGPPG 1157

Query: 367  AP----DMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPS----KQRRG 418
                  D+GS G       G+P  R    P  S    TPGL   GG G P     K  RG
Sbjct: 1158 EKGEVGDVGSMGP-----HGAPGPRGPQGPTGS--EGTPGLP--GGVGQPGAVGEKGERG 1208

Query: 419  ----PSPKTELG--GPQGSLGRASLSGPFG-PGPQG--GPPSRDRRHLGVQIGRVRVPLG 469
                P P    G  GP+G +G    SGP G  GP G  GPP  D               G
Sbjct: 1209 DAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAK------------G 1256

Query: 470  SALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFT 529
            S  P     +L PPG       D      G+ G +     +  P P  A GE        
Sbjct: 1257 SVGPTGLPGDLGPPGDPGVSGID------GSPGEKGDPGDVGGPGPPGASGEPG------ 1304

Query: 530  FRKVRNPPGPRG--------------GAMSAAGTRSPPGPAESARSRGPRPGWDTPE 572
                  PPG RG              GA    G   PPG      +RGP PG   PE
Sbjct: 1305 ---APGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGP-PGRVGPE 1357



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 90/323 (27%), Positives = 114/323 (35%), Gaps = 51/323 (15%)

Query: 297  PPRSPPRLGR--APHFNGPPAHPGPGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVK 354
            PP S    G+   P   G P  PGP      P PL P    +  +  + +  Q   EG +
Sbjct: 777  PPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGP----IGEKGKSGKTGQPGLEGER 832

Query: 355  RDGG----QGLPDVEGAP----DMGSSGE-GAGLEEGSP-LRRERAWPPPSLRTPTPGLT 404
               G    +G P   G P    D+G  G  G   E+G P L+    +P P  + P     
Sbjct: 833  GPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGP--KGPPGHQG 890

Query: 405  EGGGTGLPSKQ-------RRGPSPKTELGGPQGS------LGRASLSGPFGP-GPQGGPP 450
            + G  G P ++       + GP     + GPQG       LG     GP GP G QG P 
Sbjct: 891  KDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPG 950

Query: 451  SRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPD-------PERPC-----P 498
               R     ++G    PLG   P   R    P G      P        P  P      P
Sbjct: 951  LEGREGAKGELGPPG-PLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSP 1009

Query: 499  GTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--GAMSAAGTRSPPGPA 556
            G RG      G+  P    + G   P  +   R  R PPGP G  G     G   PPG A
Sbjct: 1010 GERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAA 1069

Query: 557  ESARSRGPRPGWDTP----EKGD 575
              +   G +     P     KGD
Sbjct: 1070 GPSGEEGDKGDVGAPGHKGSKGD 1092



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 71/237 (29%), Positives = 94/237 (39%), Gaps = 37/237 (15%)

Query: 357  GGQGLPDVEGAP-DMGSSG-EGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSK 414
            G  GLP   G P D G SG +G+  E+G P       PP +   P       G  G P K
Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEP-------GAPGPPGK 1311

Query: 415  QRRGPSPKTELGGPQGSLGRASLSGPFGPG----PQG--GPPSRDRRHLGVQ-IGRVRVP 467
              RGPS      G +G  G     GP GP     P G  GPP R    +G + +  +  P
Sbjct: 1312 --RGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGR----VGPEGLRGIPGP 1365

Query: 468  LGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRS--GREGLLSPAPRSALGETAPT 525
            +G      A  ++ PPG          +   G +G +   G  GL+ P      GE    
Sbjct: 1366 VGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPP-----GEAGEK 1420

Query: 526  AQFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESARSRGPR--PGWDTPEKGD 575
                   V+ PPGP+G     G + + G   PPG A     +G +  PG   P +GD
Sbjct: 1421 GDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGP-RGD 1476



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 78/269 (28%), Positives = 94/269 (34%), Gaps = 50/269 (18%)

Query: 312 GPPAHPG-PGRPSTSPCPLPPSLLCLWVESGT--PRGRQSLAEGVKRDGGQGLPDVEGAP 368
           GPP   G  GRP     P  P L       G   PRG Q       R G  G P  +GA 
Sbjct: 479 GPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGA- 537

Query: 369 DMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPS-KQRRGPSPKTELGG 427
                    GL   +  + +R +               G  GLP  K +RG        G
Sbjct: 538 --------RGLPGDTGPKGDRGFD--------------GLPGLPGEKGQRGDFGHVGQPG 575

Query: 428 PQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALP--YPARSEL-APPG 484
           P G  G     GP GP  Q G P   R  LG        P GS  P   P  + +   PG
Sbjct: 576 PPGEDGERGAEGPPGPTGQAGEPG-PRGLLG--------PRGSPGPTGRPGVTGIDGAPG 626

Query: 485 ARDALSPDPERPCPGTRGVRSGREGLLSPAPRSAL---GETAPTAQFTFRKVRNPPGPRG 541
           A+  + P  E   PG +G   G +GL  P P+  +   GE  P        +    GP G
Sbjct: 627 AKGNVGPPGEPGPPGQQG-NHGSQGL--PGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLG 683

Query: 542 -----GAMSAAGTRSPPGPAESARSRGPR 565
                G     G + PPG A      GPR
Sbjct: 684 HPGHEGPTGEKGAQGPPGSAGPPGYPGPR 712



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 77/270 (28%), Positives = 92/270 (34%), Gaps = 53/270 (19%)

Query: 301 PPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVKRDGGQ 359
           P  + +   F GPP  PGP G    S  P PP     +     P G   L      DG +
Sbjct: 381 PAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPG----FPGDPGPPGPAGLPGIPGIDGIR 436

Query: 360 GLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGP 419
           G P   G   M       G  +G P+  ++A     L+           T L  K   GP
Sbjct: 437 GPP---GTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQ----------TQLSMKGPPGP 483

Query: 420 SPKTELGGPQGSLGRASLSGPFG-PGPQG--------GPPSRDRRHLGVQIGRVRVPLGS 470
              T   GP G  G   L G  G  GPQG        GPP R    +G ++GR       
Sbjct: 484 VGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR----VG-KMGRPGADGAR 538

Query: 471 ALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTAQFTF 530
            LP     +  P G R     D     PG +G R     +  P P    GE         
Sbjct: 539 GLP----GDTGPKGDRGF---DGLPGLPGEKGQRGDFGHVGQPGPPGEDGE--------- 582

Query: 531 RKVRNPPGPRG-----GAMSAAGTRSPPGP 555
           R    PPGP G     G     G R  PGP
Sbjct: 583 RGAEGPPGPTGQAGEPGPRGLLGPRGSPGP 612



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 92/311 (29%), Positives = 117/311 (37%), Gaps = 62/311 (19%)

Query: 296  LPPRSPPRLGRAPHFNGPPAHPGP-GRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGVK 354
            L    P  L   P   G P  PGP G       P P         +G+P  R  L     
Sbjct: 967  LGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGA------NGSPGERGPLGPA-- 1018

Query: 355  RDGGQGLPDVEGAPD-MGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPS 413
              GG GLP   G+   +G +G+     +GS  R ER  P P+ +   PG    G  G P 
Sbjct: 1019 --GGIGLPGQSGSEGPVGPAGK-----KGS--RGERGPPGPTGKDGIPGPL--GPLGPPG 1067

Query: 414  KQRRGPS----PKTELGGP--QGSLGRASLSGPFGP----GPQG--GPPSRD----RRHL 457
                GPS     K ++G P  +GS G    +GP G     GP G  GPP  D    RR  
Sbjct: 1068 AA--GPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP 1125

Query: 458  GVQIGR-----VRVPLGSALPYPARSELAPPGAR----DALSPDPERPCPGTRGVR--SG 506
                G+     VR  +G   P   +    PPG +    D  S  P    PG RG +  +G
Sbjct: 1126 PGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP-HGAPGPRGPQGPTG 1184

Query: 507  REGLLSPAPRSALGETAPTAQFTFRKVRNPPGPRG--------GAMSAAGTRSPPGPAES 558
             EG  +P     +G+     +   R     PGP G        G +   G   P G A  
Sbjct: 1185 SEG--TPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGP 1242

Query: 559  ARSRGPRPGWD 569
               +GP PG D
Sbjct: 1243 PGKKGP-PGED 1252



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 71/268 (26%), Positives = 88/268 (32%), Gaps = 54/268 (20%)

Query: 297  PPRSPPRLG--RAPHFNGPPAHPG-PGRPSTSPCPLPPSLLCLWVESGTPRGRQSLAEGV 353
            PP  P   G   +P   G P   G PG P  S  P  P           P G++  +  +
Sbjct: 1269 PPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPG----------PPGKRGPSGHM 1318

Query: 354  KRDGGQGLPDVEGAPDM-GSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLP 412
             R+G +G    +G P   G  G    +    P  R     P  LR     + E G  G P
Sbjct: 1319 GREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVG---PEGLRGIPGPVGEPGLLGAP 1375

Query: 413  SKQRRGPSPKTELG--------GPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQ--IG 462
              Q   P P    G        GP+G  G   L G  GP  + G    D+   GVQ   G
Sbjct: 1376 G-QMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKG-DQGLPGVQGPPG 1433

Query: 463  RVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGET 522
                P G   P  +     PPG    L     +  PG+ G R               G+T
Sbjct: 1434 PKGDP-GPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPR---------------GDT 1477

Query: 523  APTAQFTFRKVRNPPGPRGGAMSAAGTR 550
             P           PPGP G      G R
Sbjct: 1478 GPA---------GPPGPPGAPAELHGLR 1496



 Score = 36.6 bits (83), Expect = 0.095
 Identities = 72/282 (25%), Positives = 99/282 (35%), Gaps = 32/282 (11%)

Query: 311 NGPPAHPGPGRPST------SPCP-LPPSLLCLWVESGTPRGRQS--LAEGVKRDGGQGL 361
           + PP      + ST      +P P LPP+   L V S    G  +  L   +  D G  L
Sbjct: 273 SSPPPDSAENQTSTDIPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTEL 332

Query: 362 PDVEG-APDMGSSGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPS 420
             +E  A      G+ + +    P  R   +P  +     PG  E G  G P+   +G  
Sbjct: 333 GTLETKAAREDEEGDDSTM---GPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQ 389

Query: 421 PKTELG--GPQGSLGRASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPAR- 477
            +   G  GPQG +G +   GP G     GPP          I  +R P G+ +  P + 
Sbjct: 390 FEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQF 449

Query: 478 ---SELAPP-----GARDALSPDPERPCPGTRGV--RSGREGLLS-PAPRSALGETAPTA 526
              S   PP         A+    +    G  G    +GR G +  P      GE     
Sbjct: 450 AGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEG 509

Query: 527 QFTFRKVRNPPGPRG-----GAMSAAGTRSPPGPAESARSRG 563
               R ++ P GP G     G   A G R  PG       RG
Sbjct: 510 PQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRG 551



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 57/217 (26%), Positives = 71/217 (32%), Gaps = 44/217 (20%)

Query: 288  PPAGHTLRLPPRSPPRLGRAPHFN--------GPPAHPGPGRPSTSPCPL----PPSLLC 335
            PP        P  P + G + H          G    PGP  P     P+    PP  + 
Sbjct: 1296 PPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRV- 1354

Query: 336  LWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPD-MGSSGEGAGLEEGSPLRRERAWPPP 394
                   P G + +   V   G  G P   G P  +G SG      +  P   +      
Sbjct: 1355 ------GPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLI 1408

Query: 395  SLRTPTPGLTEGGGTGLPSKQRRGPSPKTELG--GPQGSLGRASLSGPFGP--------- 443
             L  P     E G  GLP  Q   P PK + G  GP GSLG     G  GP         
Sbjct: 1409 GLIGPPGEAGEKGDQGLPGVQGP-PGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS 1467

Query: 444  ----GPQG--------GPPSRDRRHLGVQIGRVRVPL 468
                GP+G        GPP       G++  R  VP+
Sbjct: 1468 PGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPV 1504


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.135    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,271,658
Number of Sequences: 37866
Number of extensions: 3010826
Number of successful extensions: 17947
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 110
Number of HSP's successfully gapped in prelim test: 1103
Number of HSP's that attempted gapping in prelim test: 11151
Number of HSP's gapped (non-prelim): 4259
length of query: 800
length of database: 18,247,518
effective HSP length: 110
effective length of query: 690
effective length of database: 14,082,258
effective search space: 9716758020
effective search space used: 9716758020
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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