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Search of human proteins with 21327685
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
(773 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 1527 0.0
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] 1344 0.0
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens] 354 2e-97
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens] 312 7e-85
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens] 182 8e-46
gi|6005942 valosin-containing protein [Homo sapiens] 178 1e-44
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens] 173 5e-43
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] 167 4e-41
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] 160 3e-39
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] 160 4e-39
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] 157 5e-38
gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens] 156 6e-38
gi|157671927 spermatogenesis associated 5 [Homo sapiens] 156 6e-38
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] 154 3e-37
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] 154 3e-37
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ... 152 1e-36
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi... 152 1e-36
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens] 152 1e-36
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] 146 8e-35
gi|5901990 katanin p60 subunit A 1 [Homo sapiens] 145 1e-34
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens] 145 2e-34
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens] 145 2e-34
gi|4505725 peroxin1 [Homo sapiens] 142 1e-33
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens] 132 9e-31
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens] 128 2e-29
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 127 3e-29
gi|40806170 spastin isoform 2 [Homo sapiens] 126 9e-29
gi|11875211 spastin isoform 1 [Homo sapiens] 126 9e-29
gi|31742536 fidgetin-like 1 [Homo sapiens] 125 1e-28
gi|112789543 fidgetin-like 1 [Homo sapiens] 125 1e-28
>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
Length = 773
Score = 1527 bits (3954), Expect = 0.0
Identities = 773/773 (100%), Positives = 773/773 (100%)
Query: 1 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFS 60
MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFS
Sbjct: 1 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFS 60
Query: 61 DFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRD 120
DFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRD
Sbjct: 61 DFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRD 120
Query: 121 LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC 180
LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC
Sbjct: 121 LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC 180
Query: 181 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL 240
LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL
Sbjct: 181 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL 240
Query: 241 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL 300
LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL
Sbjct: 241 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL 300
Query: 301 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN 360
LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN
Sbjct: 301 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN 360
Query: 361 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 420
PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI
Sbjct: 361 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 420
Query: 421 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG 480
RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG
Sbjct: 421 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG 480
Query: 481 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG 540
ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG
Sbjct: 481 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG 540
Query: 541 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE 600
FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE
Sbjct: 541 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE 600
Query: 601 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA 660
SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA
Sbjct: 601 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA 660
Query: 661 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE 720
EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE
Sbjct: 661 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE 720
Query: 721 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 773
IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR
Sbjct: 721 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 773
>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
Length = 716
Score = 1344 bits (3479), Expect = 0.0
Identities = 698/773 (90%), Positives = 703/773 (90%), Gaps = 57/773 (7%)
Query: 1 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFS 60
MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSE
Sbjct: 1 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSE---- 56
Query: 61 DFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRD 120
LN+ +G ++ G +E
Sbjct: 57 ---PSLNLRDLGLSELKIGQIDQLVE---------------------------------- 79
Query: 121 LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC 180
NLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC
Sbjct: 80 ----------------NLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC 123
Query: 181 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL 240
LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL
Sbjct: 124 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL 183
Query: 241 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL 300
LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL
Sbjct: 184 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL 243
Query: 301 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN 360
LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN
Sbjct: 244 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN 303
Query: 361 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 420
PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI
Sbjct: 304 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 363
Query: 421 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG 480
RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG
Sbjct: 364 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG 423
Query: 481 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG 540
ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG
Sbjct: 424 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG 483
Query: 541 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE 600
FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE
Sbjct: 484 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE 543
Query: 601 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA 660
SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA
Sbjct: 544 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA 603
Query: 661 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE 720
EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE
Sbjct: 604 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE 663
Query: 721 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 773
IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR
Sbjct: 664 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 716
>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
Length = 797
Score = 354 bits (908), Expect = 2e-97
Identities = 192/441 (43%), Positives = 280/441 (63%), Gaps = 17/441 (3%)
Query: 335 NVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 394
+V F+ V G EEAK E+ E V FLKNP+++ LG K+PKG +L GPPGTGKTLLA+A AG
Sbjct: 304 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAG 363
Query: 395 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 454
EA+VPF SGSEF EMFVGVG +R+R+LF A+ NAPC++FIDE+D+VG KR
Sbjct: 364 EANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGG 423
Query: 455 YSRQ--TINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 512
S Q T+NQLL EMDGF V+I+ TN P+ LD AL+RPGRFD Q+ + PD+KGR
Sbjct: 424 QSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGR 483
Query: 513 TEILKWYLNKIKFDQSVDPEIIARG----TVGFSGAELENLVNQAALKAAVDGKEMVTMK 568
I K +L +K D +++ + +AR T GFSGA++ N+ N+AAL AA + + K
Sbjct: 484 ASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQK 543
Query: 569 ELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTL 628
E + ++++ G E+++ + + K AYHE+GHA+ +Y + A P+ K +I+PRG L
Sbjct: 544 HFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGL 603
Query: 629 GHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRM 688
G+ LP+ +++ T+ QLL +M +++GGR +EE+ FG ITTGA D T+ A
Sbjct: 604 GYAQYLPK-EQYLYTKEQLLDRMCMTLGGRASEEIFFG--RITTGAQDDLRKVTQSAYAQ 660
Query: 689 VTKFGMSEKLGVMTYSDTGK--------LSPETQSAIEQEIRILLRDSYERAKHILKTHA 740
+ +FGM+EK+G +++ + S T I+ E+RIL+ D+Y+R +L
Sbjct: 661 IVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKK 720
Query: 741 KEHKNLAEALLTYETLDAKEI 761
+ + +A LL E LD ++
Sbjct: 721 ADVEKVALLLLEKEVLDKNDM 741
>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
Length = 795
Score = 312 bits (800), Expect = 7e-85
Identities = 175/454 (38%), Positives = 279/454 (61%), Gaps = 20/454 (4%)
Query: 328 VDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTL 387
VD K V+F+ V G+ EAK E++E V++LK+P++F LG K+PKG LL+GPPG GKTL
Sbjct: 298 VDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTL 357
Query: 388 LARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 447
LA+AVA EA VPF +G EF E+ G+GA+R+R+LF+EA+A APC+++IDE+D+VG KR
Sbjct: 358 LAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKR 417
Query: 448 IESPMHPYS----RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVT 503
+ M +S QT+NQLL EMDG + VI++ +TN + LD AL+RPGR D V
Sbjct: 418 -STTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVF 476
Query: 504 VPRPDVKGRTEILKWYLNKIKFDQSVD--PEIIARGTVGFSGAELENLVNQAALKAAVDG 561
+ P ++ R EI + +L +K QS + +A T GFSGA++ N+ N+AAL AA +G
Sbjct: 477 IDLPTLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREG 536
Query: 562 KEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATI 621
V E++ +++L G ++S + + + + A+HESGHA++ + + + K +I
Sbjct: 537 HTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSI 596
Query: 622 MPR-GPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDN 680
PR LG +LP D+ T+ QL +M +++GGR +E L F + +T+GA D
Sbjct: 597 TPRTNAALGFAQMLP-RDQHLFTKEQLFERMCMALGGRASEALSF--NEVTSGAQDDLRK 653
Query: 681 ATKIAKRMVTKFGMSEKLGVMTYSDTGK---------LSPETQSAIEQEIRILLRDSYER 731
T+IA MV +FGM+ +G +++ + + S Q ++ E R+L+ +Y
Sbjct: 654 VTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRH 713
Query: 732 AKHILKTHAKEHKNLAEALLTYETLDAKEIQIVL 765
+ +L+ + + + LA ALL E ++ ++I+ ++
Sbjct: 714 TEKVLQDNLDKLQALANALLEKEVINYEDIEALI 747
>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
Length = 406
Score = 182 bits (463), Expect = 8e-46
Identities = 102/275 (37%), Positives = 168/275 (61%), Gaps = 10/275 (3%)
Query: 324 LDSAVDPV-------QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGI 375
L + VDP+ ++ + T+E + G+++ +E++EV+E +K+P+ F LG PKG+
Sbjct: 127 LPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGV 186
Query: 376 LLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVI 435
LL GPPGTGKTLLARAVA D F SGSE + F+G GA +R LF A+ +AP +I
Sbjct: 187 LLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSII 246
Query: 436 FIDELDSVGGKRIESPMHPYS--RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALI 493
F+DE+DS+G R+E S ++T+ +LL ++DGF+ + + +I ATN + LD+AL+
Sbjct: 247 FMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALL 306
Query: 494 RPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQA 553
RPGR D ++ P P+ + R +ILK + K+ + ++ IA G SGAE++ + +A
Sbjct: 307 RPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEA 366
Query: 554 ALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEI 588
+ A + + VT ++ E + K++ +++ I
Sbjct: 367 GMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSI 401
>gi|6005942 valosin-containing protein [Homo sapiens]
Length = 806
Score = 178 bits (452), Expect = 1e-44
Identities = 102/245 (41%), Positives = 142/245 (57%), Gaps = 5/245 (2%)
Query: 331 VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLA 389
V++ VT+E + G+E+ K+ELQE+V++ +++P KF G KG+L GPPG GKTLLA
Sbjct: 469 VEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLA 528
Query: 390 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVG---GK 446
+A+A E F G E M+ G + +R +F +A+ APCV+F DELDS+ G
Sbjct: 529 KAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGG 588
Query: 447 RIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPR 506
I R INQ+L EMDG + V IIGATN P+ +D A++RPGR D + +P
Sbjct: 589 NIGDGGGAADR-VINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPL 647
Query: 507 PDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVT 566
PD K R ILK L K + VD E +A+ T GFSGA+L + +A A + E
Sbjct: 648 PDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEI 707
Query: 567 MKELE 571
+E E
Sbjct: 708 RRERE 712
Score = 173 bits (438), Expect = 6e-43
Identities = 97/238 (40%), Positives = 141/238 (59%), Gaps = 2/238 (0%)
Query: 333 MKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARA 391
+ V ++ + G + +++E+VE L++P F +G K P+GILL GPPGTGKTL+ARA
Sbjct: 198 LNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARA 257
Query: 392 VAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESP 451
VA E F+ +G E G S +R F EA+ NAP +IFIDELD++ KR E
Sbjct: 258 VANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR-EKT 316
Query: 452 MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 511
R+ ++QLL MDG K VI++ ATN P ++D AL R GRFD +V + PD G
Sbjct: 317 HGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATG 376
Query: 512 RTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKE 569
R EIL+ + +K VD E +A T G GA+L L ++AAL+A +++ +++
Sbjct: 377 RLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLED 434
>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
Length = 433
Score = 173 bits (439), Expect = 5e-43
Identities = 96/261 (36%), Positives = 158/261 (60%), Gaps = 6/261 (2%)
Query: 324 LDSAVDPVQMK---NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVG 379
+D V +Q++ +VT+ V G +E ++L+EVVE L +P++F LG + PKG+LL G
Sbjct: 157 IDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFG 216
Query: 380 PPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDE 439
PPGTGKTL ARAVA D F GSE + +VG GA +R LF A+ C+IF DE
Sbjct: 217 PPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDE 276
Query: 440 LDSVGGKRIESPMHPYS--RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGR 497
+D++GG R + + ++T+ +L+ ++DGF P + ++ ATN P+ LD AL+RPGR
Sbjct: 277 IDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGR 336
Query: 498 FDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 557
D ++ PD++GRT I K + + ++ + E++AR +GAE+ ++ +A + A
Sbjct: 337 LDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFA 396
Query: 558 AVDGKEMVTMKELEFSKDKIL 578
+++ T K+ + +K++
Sbjct: 397 IRARRKIATEKDFLEAVNKVI 417
>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
Length = 403
Score = 167 bits (422), Expect = 4e-41
Identities = 93/238 (39%), Positives = 142/238 (59%), Gaps = 3/238 (1%)
Query: 335 NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVA 393
NV++ + G+ E +EL+EV+E L NP+ F +G PKG LL GPPGTGKTLLARAVA
Sbjct: 143 NVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVA 202
Query: 394 GEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE--SP 451
+ D F S + ++G A IR +F A+ + PC+IF+DE+D++GG+R +
Sbjct: 203 SQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTS 262
Query: 452 MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 511
++T+ +LL +MDGF V +I ATN P+ LD AL+RPGR D ++ + P+ +
Sbjct: 263 ADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQA 322
Query: 512 RTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKE 569
R +ILK + I +D E I + + GF+GA+L N+ +A + A + V ++
Sbjct: 323 RLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQED 380
>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
Length = 440
Score = 160 bits (406), Expect = 3e-39
Identities = 90/245 (36%), Positives = 145/245 (59%), Gaps = 3/245 (1%)
Query: 337 TFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGE 395
T+ + G++ QE++E VE L +P+ + +G K PKG++L GPPGTGKTLLA+AVA +
Sbjct: 183 TYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQ 242
Query: 396 ADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM--H 453
F GSE + ++G G +R LFR A+ +AP ++FIDE+D++G KR +S
Sbjct: 243 TSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGE 302
Query: 454 PYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRT 513
++T+ +LL ++DGF V +I ATN E LD ALIRPGR D ++ P PD K +
Sbjct: 303 REIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKK 362
Query: 514 EILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFS 573
I + + +++ V + + SGA+++ + +A L A + + VT ++ + S
Sbjct: 363 RIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKS 422
Query: 574 KDKIL 578
K+ +L
Sbjct: 423 KENVL 427
>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
Length = 439
Score = 160 bits (405), Expect = 4e-39
Identities = 97/271 (35%), Positives = 155/271 (57%), Gaps = 7/271 (2%)
Query: 305 IYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNP--- 361
+ G+ K+ +L + T DS V +++ E + +++QE+VE + P
Sbjct: 150 LVGVNKDSYLILE-TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNH 208
Query: 362 -QKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 420
+KF LG + PKG+L+ GPPGTGKTLLARA A + F +G + +MF+G GA +
Sbjct: 209 KEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLV 268
Query: 421 RNLFREAKANAPCVIFIDELDSVGGKRIESPM--HPYSRQTINQLLAEMDGFKPNEGVII 478
R+ F AK AP +IFIDELD++G KR +S ++T+ +LL ++DGF+PN V +
Sbjct: 269 RDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKV 328
Query: 479 IGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGT 538
I ATN + LD AL+R GR D ++ P P+ + R I++ + K+ V+ E +AR T
Sbjct: 329 IAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCT 388
Query: 539 VGFSGAELENLVNQAALKAAVDGKEMVTMKE 569
F+GA+ + + +A + A G +T ++
Sbjct: 389 DDFNGAQCKAVCVEAGMIALRRGATELTHED 419
>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
Length = 753
Score = 157 bits (396), Expect = 5e-38
Identities = 103/279 (36%), Positives = 149/279 (53%), Gaps = 28/279 (10%)
Query: 318 FRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGIL 376
FR+ GL + +K V +E + G+E+ K +L++ +E+ LK P +F +G PKG+L
Sbjct: 449 FRSVIGL------MDIKPVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGVL 502
Query: 377 LVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIF 436
L GPPG KT L RA+A F SG++ FVG + +FR+A+A+ P ++F
Sbjct: 503 LYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILF 562
Query: 437 IDELDSVGGKRIESPMH-PYSRQTINQLLAEMDG-----------------FKP--NEGV 476
+DE+DS+ G R S + ++ LL E+DG F+ N V
Sbjct: 563 LDEIDSILGARSASKTGCDVQERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSV 622
Query: 477 IIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIAR 536
+II ATN P+ LD AL+RPGR D + +P PD KGR ILK + V E +A
Sbjct: 623 MIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLENLAA 682
Query: 537 GTVGFSGAELENLVNQAALKAAVD-GKEMVTMKELEFSK 574
T FSGA+L NL +AAL A + G + T+K+ F K
Sbjct: 683 ETCFFSGADLRNLCTEAALLALQENGLDATTVKQEHFLK 721
Score = 140 bits (354), Expect = 3e-33
Identities = 85/225 (37%), Positives = 127/225 (56%), Gaps = 7/225 (3%)
Query: 343 GVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFY 401
G+ EA L+E++ L+ P+ T LG +P+G+LL GPPG GKT L RAVA EA
Sbjct: 204 GLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAELL 263
Query: 402 YASGSEFDEMFVGVGASRIRNLF---REAKANAPCVIFIDELDSVGGKRIESPMHPYSRQ 458
S G +R +F RE + P ++F+DE+D++ +R P SR
Sbjct: 264 AVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQR--GSRAPESR- 320
Query: 459 TINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKW 518
+ Q+L +DG + V+++GATN P+ALD AL RPGRFD +V + P +K R EIL+
Sbjct: 321 VVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKEILQV 380
Query: 519 YLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKE 563
+K+ VD ++A TVG+ GA+L L +AA+ A + ++
Sbjct: 381 ITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSEK 425
>gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens]
Length = 489
Score = 156 bits (395), Expect = 6e-38
Identities = 80/146 (54%), Positives = 109/146 (74%), Gaps = 5/146 (3%)
Query: 328 VDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTL 387
VD K V+F+ V G+ EAK E++E V++LK+P++F LG K+PKG LL+GPPG GKTL
Sbjct: 298 VDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTL 357
Query: 388 LARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 447
LA+AVA EA VPF +G EF E+ G+GA+R+R+LF+EA+A APC+++IDE+D+VG KR
Sbjct: 358 LAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKR 417
Query: 448 IESPMHPYS----RQTINQLLAEMDG 469
+ M +S QT+NQLL EMDG
Sbjct: 418 -STTMSGFSNTEEEQTLNQLLVEMDG 442
>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
Length = 893
Score = 156 bits (395), Expect = 6e-38
Identities = 88/229 (38%), Positives = 135/229 (58%), Gaps = 2/229 (0%)
Query: 331 VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLA 389
+ + NV++ + G+E K +L++ VE+ LK+P+ F +G + PKG+LL GPPG KT++A
Sbjct: 619 IDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIA 678
Query: 390 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE 449
+A+A E+ + F G E +VG +R FR+A+A AP +IF DELD++ +R
Sbjct: 679 KALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVERGS 738
Query: 450 S-PMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 508
S + + + QLL EMDG + + V I+ ATN P+ +D AL+RPGR D + VP PD
Sbjct: 739 SLGAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPDRIDKALMRPGRIDRIIYVPLPD 798
Query: 509 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 557
R EI K + + VD + + T +SGAE+ + +AAL A
Sbjct: 799 AATRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAALLA 847
Score = 144 bits (362), Expect = 4e-34
Identities = 87/228 (38%), Positives = 134/228 (58%), Gaps = 8/228 (3%)
Query: 336 VTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 394
VT++ + G+ + ++E++E LK P+ F G P+G+LL GPPGTGKT++ARAVA
Sbjct: 350 VTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVAN 409
Query: 395 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 454
E +G E F G +++R +F EA P +IFIDELD++ KR E +
Sbjct: 410 EVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKR-EGAQNE 468
Query: 455 YSRQTINQLLAEMDGF--KPNEG-VIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 511
++ + LL MDG + +EG V+++GATN P ALD AL RPGRFD ++ + P+ +
Sbjct: 469 VEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQD 528
Query: 512 RTEILKWYLNKIKFDQSVDPEI--IARGTVGFSGAELENLVNQAALKA 557
R +IL+ L ++ + E+ +A G+ GA+L+ L N+A L A
Sbjct: 529 RLDILQKLLRRVP-HLLTEAELLQLANSAHGYVGADLKVLCNEAGLCA 575
>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
Length = 750
Score = 154 bits (389), Expect = 3e-37
Identities = 91/229 (39%), Positives = 133/229 (58%), Gaps = 4/229 (1%)
Query: 332 QMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARA 391
Q+ NV FE V G + +E+ +++ +++P+ + LG P+G+LL GPPG GKTLLA A
Sbjct: 152 QISNVKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHA 211
Query: 392 VAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESP 451
+AGE D+P + E G ++R LF +A +NAPC+IFIDE+D++ KR E
Sbjct: 212 IAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKR-EVA 270
Query: 452 MHPYSRQTINQLLAEMDGFK---PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 508
R+ + QLL MD V++IGATN P++LD AL R GRFD ++ + PD
Sbjct: 271 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 330
Query: 509 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 557
R IL+ K++ Q+ D +A T GF GA+L L +AA+ A
Sbjct: 331 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCA 379
Score = 149 bits (375), Expect = 1e-35
Identities = 92/234 (39%), Positives = 136/234 (58%), Gaps = 9/234 (3%)
Query: 331 VQMKNVTFEHVKGVEEAKQEL-QEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLA 389
V + NVT+ + +E+ ++EL ++ ++NP +F LG P G+LL GPPG GKTLLA
Sbjct: 467 VTVPNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLA 526
Query: 390 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE 449
+AVA E+ + F G E M+VG +R +F+ AK +APCVIF DE+D++ +R +
Sbjct: 527 KAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSD 586
Query: 450 SPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDV 509
S + +NQLL EMDG + + V I+ ATN P+ +D A++RPGR D + V P
Sbjct: 587 RETGA-SVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPP 645
Query: 510 KGRTEILKWYL---NKIKFDQSVDPEIIARGTVG---FSGAELENLVNQAALKA 557
R ILK K D V+ E IA G + ++GA+L LV +A++ A
Sbjct: 646 ADRLAILKTITKNGTKPPLDADVNLEAIA-GDLRCDCYTGADLSALVREASICA 698
>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
Length = 856
Score = 154 bits (389), Expect = 3e-37
Identities = 91/229 (39%), Positives = 133/229 (58%), Gaps = 4/229 (1%)
Query: 332 QMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARA 391
Q+ NV FE V G + +E+ +++ +++P+ + LG P+G+LL GPPG GKTLLA A
Sbjct: 258 QISNVKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHA 317
Query: 392 VAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESP 451
+AGE D+P + E G ++R LF +A +NAPC+IFIDE+D++ KR E
Sbjct: 318 IAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKR-EVA 376
Query: 452 MHPYSRQTINQLLAEMDGFK---PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 508
R+ + QLL MD V++IGATN P++LD AL R GRFD ++ + PD
Sbjct: 377 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 436
Query: 509 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 557
R IL+ K++ Q+ D +A T GF GA+L L +AA+ A
Sbjct: 437 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCA 485
Score = 149 bits (375), Expect = 1e-35
Identities = 92/234 (39%), Positives = 136/234 (58%), Gaps = 9/234 (3%)
Query: 331 VQMKNVTFEHVKGVEEAKQEL-QEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLA 389
V + NVT+ + +E+ ++EL ++ ++NP +F LG P G+LL GPPG GKTLLA
Sbjct: 573 VTVPNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLA 632
Query: 390 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE 449
+AVA E+ + F G E M+VG +R +F+ AK +APCVIF DE+D++ +R +
Sbjct: 633 KAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSD 692
Query: 450 SPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDV 509
S + +NQLL EMDG + + V I+ ATN P+ +D A++RPGR D + V P
Sbjct: 693 RETGA-SVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPP 751
Query: 510 KGRTEILKWYL---NKIKFDQSVDPEIIARGTVG---FSGAELENLVNQAALKA 557
R ILK K D V+ E IA G + ++GA+L LV +A++ A
Sbjct: 752 ADRLAILKTITKNGTKPPLDADVNLEAIA-GDLRCDCYTGADLSALVREASICA 804
>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
[Homo sapiens]
Length = 414
Score = 152 bits (383), Expect = 1e-36
Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%)
Query: 332 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 390
Q +V + + G++ KQE++E VE L + + + +G P+G+L+ GPPG GKT+LA+
Sbjct: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213
Query: 391 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 450
AVA F GSEF + ++G G +R++FR AK NAP +IFIDE+D++ KR ++
Sbjct: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273
Query: 451 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 508
++ + +LL +MDGF N V +I ATN + LD AL+RPGR D ++ P PD
Sbjct: 274 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 333
Query: 509 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 568
+ + I +K+ + VD E SGA++ ++ ++ + A + + +V K
Sbjct: 334 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 393
Query: 569 ELEFSKDKILMGPER 583
+ E + ++ E+
Sbjct: 394 DFEKAYKTVIKKDEQ 408
>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
sapiens]
Length = 387
Score = 152 bits (383), Expect = 1e-36
Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%)
Query: 332 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 390
Q +V + + G++ KQE++E VE L + + + +G P+G+L+ GPPG GKT+LA+
Sbjct: 127 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 186
Query: 391 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 450
AVA F GSEF + ++G G +R++FR AK NAP +IFIDE+D++ KR ++
Sbjct: 187 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 246
Query: 451 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 508
++ + +LL +MDGF N V +I ATN + LD AL+RPGR D ++ P PD
Sbjct: 247 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 306
Query: 509 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 568
+ + I +K+ + VD E SGA++ ++ ++ + A + + +V K
Sbjct: 307 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 366
Query: 569 ELEFSKDKILMGPER 583
+ E + ++ E+
Sbjct: 367 DFEKAYKTVIKKDEQ 381
>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
Length = 418
Score = 152 bits (383), Expect = 1e-36
Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%)
Query: 332 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 390
Q +V + + G++ KQE++E VE L + + + +G P+G+L+ GPPG GKT+LA+
Sbjct: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
Query: 391 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 450
AVA F GSEF + ++G G +R++FR AK NAP +IFIDE+D++ KR ++
Sbjct: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277
Query: 451 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 508
++ + +LL +MDGF N V +I ATN + LD AL+RPGR D ++ P PD
Sbjct: 278 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 337
Query: 509 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 568
+ + I +K+ + VD E SGA++ ++ ++ + A + + +V K
Sbjct: 338 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 397
Query: 569 ELEFSKDKILMGPER 583
+ E + ++ E+
Sbjct: 398 DFEKAYKTVIKKDEQ 412
>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
Length = 980
Score = 146 bits (368), Expect = 8e-35
Identities = 102/282 (36%), Positives = 149/282 (52%), Gaps = 19/282 (6%)
Query: 306 YGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKF 364
+ LL F + T AV ++ +V++ V G++E K+E+ E ++ L++P+
Sbjct: 672 FPLLAEDFGQALEQLQTAHSQAVGAPKIPSVSWHDVGGLQEVKKEILETIQLPLEHPELL 731
Query: 365 TILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLF 424
++ G G+LL GPPGTGKTLLA+AVA E + F G E M+VG +R +F
Sbjct: 732 SL--GLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVF 789
Query: 425 REAKANAPCVIFIDELDSVGGKRIES-PMHPYSRQTINQLLAEMDGFKPNEGVIIIGATN 483
A+A APC+IF DELDS+ R S + ++QLLAE+DG + V +IGATN
Sbjct: 790 ARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATN 849
Query: 484 FPEALDNALIRPGRFDMQVTV-PRPDVKGRTEILKWYLNKIKFDQSVD-PEIIARGTVGF 541
P+ LD AL+RPGRFD V V D + +L K K + SV ++
Sbjct: 850 RPDLLDPALLRPGRFDKLVFVGANEDRASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQL 909
Query: 542 SGAELENLVNQ---AALKAAVDGKE----------MVTMKEL 570
+GA+L +L + AALK V E M+TM++L
Sbjct: 910 TGADLYSLCSDAMTAALKRRVHDLEEGLEPGSSALMLTMEDL 951
Score = 43.1 bits (100), Expect = 0.001
Identities = 50/218 (22%), Positives = 82/218 (37%), Gaps = 11/218 (5%)
Query: 343 GVEEAKQELQEVVEFLKNPQKFTILGGKLPKG---ILLVGPPGTGKTLLARAVAGEADVP 399
G+E EL V++ P GG L G +LL GPPG GKT + A +
Sbjct: 437 GLEALVSELCAVLKPRLQP------GGALLTGTSSVLLRGPPGCGKTTVVAAACSHLGLH 490
Query: 400 FYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQT 459
S G ++++ +F A+ P V+ + +D +G R
Sbjct: 491 LLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAVLLLTAVDLLGRDRDGLGEDARVMAV 550
Query: 460 INQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWY 519
+ LL D ++++ T+ A D F ++ VP R IL+
Sbjct: 551 LRHLLLNEDPLNSCPPLMVVATTS--RAQDLPADVQTAFPHELEVPALSEGQRLSILRAL 608
Query: 520 LNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 557
+ Q V+ +AR GF +L L+ ++ A
Sbjct: 609 TAHLPLGQEVNLAQLARRCAGFVVGDLYALLTHSSRAA 646
>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
Length = 491
Score = 145 bits (367), Expect = 1e-34
Identities = 100/278 (35%), Positives = 154/278 (55%), Gaps = 16/278 (5%)
Query: 332 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLLA 389
Q NV ++ + + EAK+ L+E V + P+ F G + P KG+L+VGPPGTGKTLLA
Sbjct: 202 QNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKTLLA 259
Query: 390 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE 449
+AVA E F+ S S + G +R LF A+ +P IFIDE+DS+ +R
Sbjct: 260 KAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGT 319
Query: 450 SPMHPYSRQTINQLLAEMDGF-------KPNEGVIIIGATNFPEALDNALIRPGRFDMQV 502
S H SR+ +LL +MDG P++ V+++ ATNFP +D AL R R + ++
Sbjct: 320 SEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRI 377
Query: 503 TVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGK 562
+P P KGR E+L+ L +++ VD IA G+SGA++ N+ A+L A
Sbjct: 378 YIPLPSAKGREELLRISLRELELADDVDLASIAENMEGYSGADITNVCRDASLMAMRRRI 437
Query: 563 EMVTMKEL-EFSKDKILMGPERRSVEIDNK--NKTITA 597
E +T +E+ SK+++ M E+ K +K+++A
Sbjct: 438 EGLTPEEIRNLSKEEMHMPTTMEDFEMALKKVSKSVSA 475
>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
Length = 490
Score = 145 bits (365), Expect = 2e-34
Identities = 97/275 (35%), Positives = 154/275 (56%), Gaps = 16/275 (5%)
Query: 335 NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLLARAV 392
++ ++ + +EEAK+ L+E V + P F G + P KG+L+VGPPGTGKT+LA+AV
Sbjct: 204 SIHWDDIADLEEAKKLLREAVVLPMWMPDFFK--GIRRPWKGVLMVGPPGTGKTMLAKAV 261
Query: 393 AGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM 452
A E F+ S S + G +R LF A+ AP IFIDE+DS+ +R S
Sbjct: 262 ATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDE 321
Query: 453 HPYSRQTINQLLAEMDGF-------KPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVP 505
H SR+ ++LL +MDG P++ V+++ ATNFP +D AL R R + ++ +P
Sbjct: 322 HEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIYIP 379
Query: 506 RPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMV 565
P KGR E+LK L +++ D + E IA G+SGA++ N+ A+L A +
Sbjct: 380 LPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGL 439
Query: 566 TMKELE-FSKDKILMGPERRSVEIDNKN--KTITA 597
+ +E+ SK+++ M + E+ K K+++A
Sbjct: 440 SPEEIRALSKEELQMPVTKGDFELALKKIAKSVSA 474
>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
Length = 490
Score = 145 bits (365), Expect = 2e-34
Identities = 97/275 (35%), Positives = 154/275 (56%), Gaps = 16/275 (5%)
Query: 335 NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLLARAV 392
++ ++ + +EEAK+ L+E V + P F G + P KG+L+VGPPGTGKT+LA+AV
Sbjct: 204 SIHWDDIADLEEAKKLLREAVVLPMWMPDFFK--GIRRPWKGVLMVGPPGTGKTMLAKAV 261
Query: 393 AGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM 452
A E F+ S S + G +R LF A+ AP IFIDE+DS+ +R S
Sbjct: 262 ATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDE 321
Query: 453 HPYSRQTINQLLAEMDGF-------KPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVP 505
H SR+ ++LL +MDG P++ V+++ ATNFP +D AL R R + ++ +P
Sbjct: 322 HEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIYIP 379
Query: 506 RPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMV 565
P KGR E+LK L +++ D + E IA G+SGA++ N+ A+L A +
Sbjct: 380 LPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGL 439
Query: 566 TMKELE-FSKDKILMGPERRSVEIDNKN--KTITA 597
+ +E+ SK+++ M + E+ K K+++A
Sbjct: 440 SPEEIRALSKEELQMPVTKGDFELALKKIAKSVSA 474
>gi|4505725 peroxin1 [Homo sapiens]
Length = 1283
Score = 142 bits (358), Expect = 1e-33
Identities = 80/225 (35%), Positives = 127/225 (56%), Gaps = 2/225 (0%)
Query: 334 KNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAV 392
+++ ++ + G+ E +Q L + ++ K P+ F L + GILL GPPGTGKTLLA +
Sbjct: 835 RDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVI 894
Query: 393 AGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM 452
A E+ + F G E ++G +R++F A+A PC++F DE +S+ +R
Sbjct: 895 ARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNT 954
Query: 453 HPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 512
R +NQLL ++DG + +GV ++ AT+ P+ +D AL+RPGR D V P PD R
Sbjct: 955 GVTDR-VVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSR 1013
Query: 513 TEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 557
EIL + + VD + +A T F+GA+L+ L+ A L+A
Sbjct: 1014 LEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEA 1058
>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
Length = 444
Score = 132 bits (333), Expect = 9e-31
Identities = 85/231 (36%), Positives = 135/231 (58%), Gaps = 10/231 (4%)
Query: 331 VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLL 388
++ NV + V G+E AK+ L+E V +K P FT G + P +GILL GPPGTGK+ L
Sbjct: 126 IERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFT--GKRTPWRGILLFGPPGTGKSYL 183
Query: 389 ARAVAGEAD-VPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 447
A+AVA EA+ F+ S S+ ++G ++NLF+ A+ N P +IFIDE+DS+ G R
Sbjct: 184 AKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSR 243
Query: 448 IESPMHPYSRQTINQLLAEMDGF-KPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPR 506
E+ +R+ + L +M G N+G++++GATN P LD+A+ R RF+ ++ +P
Sbjct: 244 SENESEA-ARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRR--RFEKRIYIPL 300
Query: 507 PDVKGRTEILKWYLNKIKFD-QSVDPEIIARGTVGFSGAELENLVNQAALK 556
P+ R + K +L + D + R T G+SGA++ +V A ++
Sbjct: 301 PEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQ 351
>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
Length = 437
Score = 128 bits (322), Expect = 2e-29
Identities = 83/232 (35%), Positives = 137/232 (59%), Gaps = 12/232 (5%)
Query: 331 VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLL 388
++ N+ + V G+E AK+ L+E V +K P FT G + P +GILL GPPGTGK+ L
Sbjct: 119 MEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFT--GKRTPWRGILLFGPPGTGKSYL 176
Query: 389 ARAVAGEAD-VPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 447
A+AVA EA+ F+ S S+ ++G ++NLF A+ + P +IFIDE+DS+ G R
Sbjct: 177 AKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSR 236
Query: 448 IESPMHPYSRQTINQLLAEMDGF-KPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPR 506
E+ +R+ + L +M G N+G +++GATN P LD+A+ R RF+ ++ +P
Sbjct: 237 NENESEA-ARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR--RFEKRIYIPL 293
Query: 507 PDVKGRTEILKWYLNKIKFDQSVDPEI--IARGTVGFSGAELENLVNQAALK 556
P+ R ++ + +L + + D I +AR T G+SGA++ +V + ++
Sbjct: 294 PEEAARAQMFRLHLGSTPHNLT-DANIHELARKTEGYSGADISIIVRDSLMQ 344
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 127 bits (320), Expect = 3e-29
Identities = 88/240 (36%), Positives = 130/240 (54%), Gaps = 13/240 (5%)
Query: 328 VDPVQM-KNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGK 385
VDP+Q+ +V F+ V G+ L+E+V F L P+ F + P+G L GPPGTGK
Sbjct: 414 VDPMQLDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGK 473
Query: 386 TLLARAVAGEAD-----VPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDEL 440
TL+ARA+A E V F+ G++ +VG ++R LF +A P +IF DE+
Sbjct: 474 TLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEI 533
Query: 441 DSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDM 500
D + R S ++ LLA MDG +++IGATN +++D AL RPGRFD
Sbjct: 534 DGLAPVR-SSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDR 592
Query: 501 QVTVPRPDVKGRTEILKWYL---NKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 557
+ PD + R EILK + N D + E +A VG+ GA+++++ +AAL A
Sbjct: 593 EFLFSLPDKEARKEILKIHTRDWNPKPLDTFL--EELAENCVGYCGADIKSICAEAALCA 650
>gi|40806170 spastin isoform 2 [Homo sapiens]
Length = 584
Score = 126 bits (316), Expect = 9e-29
Identities = 94/266 (35%), Positives = 148/266 (55%), Gaps = 21/266 (7%)
Query: 336 VTFEHVKGVEEAKQELQEVVEFLK-NPQKFTILGGKLP-KGILLVGPPGTGKTLLARAVA 393
V F+ + G + AKQ LQE+V P+ FT G + P +G+LL GPPG GKT+LA+AVA
Sbjct: 307 VKFDDIAGQDLAKQALQEIVILPSLRPELFT--GLRAPARGLLLFGPPGNGKTMLAKAVA 364
Query: 394 GEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMH 453
E++ F+ S + +VG G +R LF A+ P +IFIDE+DS+ +R E H
Sbjct: 365 AESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGE-H 423
Query: 454 PYSRQTINQLLAEMDGFKP--NEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 511
SR+ + L E DG + ++ V+++GATN P+ LD A++R RF +V V P+ +
Sbjct: 424 DASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLR--RFIKRVYVSLPNEET 481
Query: 512 RTEILKWYLNKIKFDQSVDPEI--IARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKE 569
R +LK L K + E+ +AR T G+SG++L L AAL ++E
Sbjct: 482 RLLLLKNLLCK-QGSPLTQKELAQLARMTDGYSGSDLTALAKDAALG---------PIRE 531
Query: 570 LEFSKDKILMGPERRSVEIDNKNKTI 595
L+ + K + E R++ + + +++
Sbjct: 532 LKPEQVKNMSASEMRNIRLSDFTESL 557
>gi|11875211 spastin isoform 1 [Homo sapiens]
Length = 616
Score = 126 bits (316), Expect = 9e-29
Identities = 94/266 (35%), Positives = 148/266 (55%), Gaps = 21/266 (7%)
Query: 336 VTFEHVKGVEEAKQELQEVVEFLK-NPQKFTILGGKLP-KGILLVGPPGTGKTLLARAVA 393
V F+ + G + AKQ LQE+V P+ FT G + P +G+LL GPPG GKT+LA+AVA
Sbjct: 339 VKFDDIAGQDLAKQALQEIVILPSLRPELFT--GLRAPARGLLLFGPPGNGKTMLAKAVA 396
Query: 394 GEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMH 453
E++ F+ S + +VG G +R LF A+ P +IFIDE+DS+ +R E H
Sbjct: 397 AESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGE-H 455
Query: 454 PYSRQTINQLLAEMDGFKP--NEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 511
SR+ + L E DG + ++ V+++GATN P+ LD A++R RF +V V P+ +
Sbjct: 456 DASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLR--RFIKRVYVSLPNEET 513
Query: 512 RTEILKWYLNKIKFDQSVDPEI--IARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKE 569
R +LK L K + E+ +AR T G+SG++L L AAL ++E
Sbjct: 514 RLLLLKNLLCK-QGSPLTQKELAQLARMTDGYSGSDLTALAKDAALG---------PIRE 563
Query: 570 LEFSKDKILMGPERRSVEIDNKNKTI 595
L+ + K + E R++ + + +++
Sbjct: 564 LKPEQVKNMSASEMRNIRLSDFTESL 589
>gi|31742536 fidgetin-like 1 [Homo sapiens]
Length = 674
Score = 125 bits (314), Expect = 1e-28
Identities = 80/224 (35%), Positives = 127/224 (56%), Gaps = 8/224 (3%)
Query: 336 VTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 394
V +E + GVE AK ++E+V + + P FT L G PKGILL GPPGTGKTL+ + +A
Sbjct: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGP-PKGILLFGPPGTGKTLIGKCIAS 456
Query: 395 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 454
++ F+ S S +VG G +R LF A+ P VIFIDE+DS+ +R + H
Sbjct: 457 QSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGE-HE 515
Query: 455 YSRQTINQLLAEMDG--FKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 512
SR+ + L ++DG + ++++GATN P+ +D A R R ++ +P P+ R
Sbjct: 516 SSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASAR 573
Query: 513 TEILKWYLNKIKFDQSVDP-EIIARGTVGFSGAELENLVNQAAL 555
+I+ ++K + S + E I + + FSGA++ L +A+L
Sbjct: 574 KQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASL 617
>gi|112789543 fidgetin-like 1 [Homo sapiens]
Length = 674
Score = 125 bits (314), Expect = 1e-28
Identities = 80/224 (35%), Positives = 127/224 (56%), Gaps = 8/224 (3%)
Query: 336 VTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 394
V +E + GVE AK ++E+V + + P FT L G PKGILL GPPGTGKTL+ + +A
Sbjct: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGP-PKGILLFGPPGTGKTLIGKCIAS 456
Query: 395 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 454
++ F+ S S +VG G +R LF A+ P VIFIDE+DS+ +R + H
Sbjct: 457 QSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGE-HE 515
Query: 455 YSRQTINQLLAEMDG--FKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 512
SR+ + L ++DG + ++++GATN P+ +D A R R ++ +P P+ R
Sbjct: 516 SSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASAR 573
Query: 513 TEILKWYLNKIKFDQSVDP-EIIARGTVGFSGAELENLVNQAAL 555
+I+ ++K + S + E I + + FSGA++ L +A+L
Sbjct: 574 KQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASL 617
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,026,226
Number of Sequences: 37866
Number of extensions: 1173736
Number of successful extensions: 3326
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3167
Number of HSP's gapped (non-prelim): 96
length of query: 773
length of database: 18,247,518
effective HSP length: 110
effective length of query: 663
effective length of database: 14,082,258
effective search space: 9336537054
effective search space used: 9336537054
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.