Guide to the Human Genome
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Search of human proteins with 20336190

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20336190 paired basic amino acid cleaving system 4 isoform d
preproprotein [Homo sapiens]
         (652 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20336190 paired basic amino acid cleaving system 4 isoform d ...  1360   0.0  
gi|27894285 paired basic amino acid cleaving system 4 isoform f ...  1323   0.0  
gi|20336188 paired basic amino acid cleaving system 4 isoform e ...  1295   0.0  
gi|20336184 paired basic amino acid cleaving system 4 isoform h ...  1294   0.0  
gi|20336182 paired basic amino acid cleaving system 4 isoform g ...  1294   0.0  
gi|4505577 paired basic amino acid cleaving system 4 isoform a p...  1294   0.0  
gi|20336180 paired basic amino acid cleaving system 4 isoform b ...  1294   0.0  
gi|20336186 paired basic amino acid cleaving system 4 isoform c ...   992   0.0  
gi|20336246 proprotein convertase subtilisin/kexin type 5 prepro...   835   0.0  
gi|4505579 furin preproprotein [Homo sapiens]                         647   0.0  
gi|76443679 proprotein convertase subtilisin/kexin type 4 [Homo ...   587   e-167
gi|20336242 proprotein convertase subtilisin/kexin type 1 prepro...   583   e-166
gi|20336244 proprotein convertase subtilisin/kexin type 2 [Homo ...   484   e-136
gi|20336248 proprotein convertase subtilisin/kexin type 7 prepro...   446   e-125
gi|171543895 ataxin 2 [Homo sapiens]                                   49   2e-05
gi|28269693 xylosyltransferase I [Homo sapiens]                        46   1e-04
gi|4758392 forkhead box D1 [Homo sapiens]                              45   2e-04
gi|153792074 proline rich 12 [Homo sapiens]                            45   2e-04
gi|40353727 synaptopodin isoform A [Homo sapiens]                      43   8e-04
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    42   0.001
gi|87299628 biorientation of chromosomes in cell division 1-like...    42   0.001
gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo ...    42   0.002
gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo ...    42   0.002
gi|32171221 GRP1 (general receptor for phosphoinositides 1)-asso...    41   0.003
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]          41   0.004
gi|5454106 TBP-related factor 10 [Homo sapiens]                        40   0.007
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]                40   0.007
gi|39812378 RAN binding protein 9 [Homo sapiens]                       39   0.012
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    39   0.012
gi|82546824 forkhead box K1 [Homo sapiens]                             39   0.012

>gi|20336190 paired basic amino acid cleaving system 4 isoform d
           preproprotein [Homo sapiens]
          Length = 652

 Score = 1360 bits (3520), Expect = 0.0
 Identities = 652/652 (100%), Positives = 652/652 (100%)

Query: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60

Query: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
           CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120

Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
           SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180

Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
           RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240

Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
           SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300

Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
           IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360

Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
           TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420

Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
           VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480

Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
           VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540

Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
           HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600

Query: 601 QWTLEIQDLPSQVRNPEKQGDLETPVANQLTTEEREPGLKHVFRWQIEQELW 652
           QWTLEIQDLPSQVRNPEKQGDLETPVANQLTTEEREPGLKHVFRWQIEQELW
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGDLETPVANQLTTEEREPGLKHVFRWQIEQELW 652


>gi|27894285 paired basic amino acid cleaving system 4 isoform f
           preproprotein [Homo sapiens]
          Length = 664

 Score = 1323 bits (3425), Expect = 0.0
 Identities = 638/648 (98%), Positives = 640/648 (98%), Gaps = 1/648 (0%)

Query: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60

Query: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
           CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120

Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
           SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180

Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
           RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240

Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
           SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300

Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
           IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360

Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
           TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420

Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
           VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480

Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
           VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540

Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
           HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600

Query: 601 QWTLEIQDLPSQVRNPEKQGDLETPVANQLTTEER-EPGLKHVFRWQI 647
           QWTLEIQDLPSQVRNPEKQGDLETPVANQLTTEER    L  +F W +
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGDLETPVANQLTTEERFVSTLSILFHWSV 648


>gi|20336188 paired basic amino acid cleaving system 4 isoform e
           preproprotein [Homo sapiens]
          Length = 623

 Score = 1295 bits (3352), Expect = 0.0
 Identities = 621/623 (99%), Positives = 623/623 (100%)

Query: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60

Query: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
           CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120

Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
           SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180

Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
           RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240

Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
           SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300

Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
           IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360

Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
           TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420

Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
           VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480

Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
           VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540

Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
           HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600

Query: 601 QWTLEIQDLPSQVRNPEKQGDLE 623
           QWTLEIQDLPSQVRNPEKQG+L+
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGNLD 623


>gi|20336184 paired basic amino acid cleaving system 4 isoform h
           preproprotein [Homo sapiens]
          Length = 962

 Score = 1294 bits (3349), Expect = 0.0
 Identities = 621/623 (99%), Positives = 622/623 (99%)

Query: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60

Query: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
           CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120

Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
           SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180

Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
           RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240

Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
           SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300

Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
           IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360

Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
           TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420

Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
           VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480

Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
           VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540

Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
           HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600

Query: 601 QWTLEIQDLPSQVRNPEKQGDLE 623
           QWTLEIQDLPSQVRNPEKQG L+
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGKLK 623


>gi|20336182 paired basic amino acid cleaving system 4 isoform g
           preproprotein [Homo sapiens]
          Length = 975

 Score = 1294 bits (3349), Expect = 0.0
 Identities = 621/623 (99%), Positives = 622/623 (99%)

Query: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60

Query: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
           CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120

Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
           SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180

Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
           RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240

Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
           SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300

Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
           IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360

Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
           TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420

Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
           VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480

Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
           VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540

Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
           HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600

Query: 601 QWTLEIQDLPSQVRNPEKQGDLE 623
           QWTLEIQDLPSQVRNPEKQG L+
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGKLK 623


>gi|4505577 paired basic amino acid cleaving system 4 isoform a
           preproprotein [Homo sapiens]
          Length = 969

 Score = 1294 bits (3349), Expect = 0.0
 Identities = 621/623 (99%), Positives = 622/623 (99%)

Query: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60

Query: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
           CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120

Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
           SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180

Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
           RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240

Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
           SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300

Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
           IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360

Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
           TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420

Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
           VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480

Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
           VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540

Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
           HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600

Query: 601 QWTLEIQDLPSQVRNPEKQGDLE 623
           QWTLEIQDLPSQVRNPEKQG L+
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGKLK 623


>gi|20336180 paired basic amino acid cleaving system 4 isoform b
           preproprotein [Homo sapiens]
          Length = 956

 Score = 1294 bits (3349), Expect = 0.0
 Identities = 621/623 (99%), Positives = 622/623 (99%)

Query: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60

Query: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
           CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120

Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
           SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180

Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
           RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240

Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
           SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300

Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
           IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360

Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
           TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420

Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
           VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480

Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
           VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540

Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
           HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600

Query: 601 QWTLEIQDLPSQVRNPEKQGDLE 623
           QWTLEIQDLPSQVRNPEKQG L+
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGKLK 623


>gi|20336186 paired basic amino acid cleaving system 4 isoform c
           preproprotein [Homo sapiens]
          Length = 487

 Score =  992 bits (2564), Expect = 0.0
 Identities = 471/471 (100%), Positives = 471/471 (100%)

Query: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1   MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60

Query: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
           CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61  CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120

Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
           SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180

Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
           RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240

Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
           SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300

Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
           IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360

Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
           TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420

Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHK 471
           VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHK
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHK 471


>gi|20336246 proprotein convertase subtilisin/kexin type 5
           preproprotein [Homo sapiens]
          Length = 913

 Score =  835 bits (2158), Expect = 0.0
 Identities = 391/588 (66%), Positives = 471/588 (80%), Gaps = 2/588 (0%)

Query: 38  GPGFRPLAPRPWRWLLLLALPAACSAPPPRP-VYTNHWAVQVLGGPAEADRVAAAHGYLN 96
           G G R   P     L +LAL   C  P  R  VYTNHWAV++ GG  EA+R+A+ +G++N
Sbjct: 2   GWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFIN 61

Query: 97  LGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVR-SDP 155
           +GQIG L+DYYHFYHS+T KRS +SSRG H+F+ M+P+V+W+QQQ VK+R KR    S  
Sbjct: 62  IGQIGALKDYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRA 121

Query: 156 QALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDL 215
           Q+ YFNDP W +MWY+HC D    C+S+MN++ AWKRGYTGKN+VVTILDDGIER HPDL
Sbjct: 122 QSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDL 181

Query: 216 APNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGG 275
             NYD+ AS DVNGND DP PRYDASNENKHGTRCAGEVAA+ANNS+C VGIA+NAKIGG
Sbjct: 182 MQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGG 241

Query: 276 IRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQ 335
           +RMLDGDVTD+VEAKS+   P ++ IYSASWGPDDDGKTVDGP  L +QAFE G++ GR+
Sbjct: 242 VRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRR 301

Query: 336 GLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSS 395
           GLGS+FVWASGNGGR  D+CSCDGYTNSIYTIS+SS  E+G KPWYLEEC+STLATTYSS
Sbjct: 302 GLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSS 361

Query: 396 GAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRP 455
           G  Y++KI+TTDLRQRCTD HTGTS SAPM AGIIALALEAN  LTWRDVQH++V+TSR 
Sbjct: 362 GESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRA 421

Query: 456 AHLKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPL 515
            HL A+DWK N AG KVSH YGFGL+DAEA+V+EA+KWT VP QH+CV ++D++ ++I  
Sbjct: 422 GHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRP 481

Query: 516 VQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRL 575
              +R+    S C+++ ++ V YLEHVVVR +I+HPRRGDL IYL SPSGT+SQLLA RL
Sbjct: 482 NSAVRSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRL 541

Query: 576 LDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGDLE 623
            D S EGF NWEFMT+HCWGE+A G W LE+ D PSQ+RN +  G L+
Sbjct: 542 FDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLK 589


>gi|4505579 furin preproprotein [Homo sapiens]
          Length = 794

 Score =  647 bits (1668), Expect = 0.0
 Identities = 324/565 (57%), Positives = 400/565 (70%), Gaps = 18/565 (3%)

Query: 47  RPWRWLLLLA---LPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNL 103
           RPW   ++ A   L    +    + V+TN WAV++ GGPA A+ VA  HG+LNLGQI   
Sbjct: 4   RPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--F 61

Query: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDP 163
            DYYHF+H    KRS    R  H+ L+ +PQV+WL+QQ  KRR KR V  +P      DP
Sbjct: 62  GDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP-----TDP 116

Query: 164 IWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYA 223
            +   WYL     +   + ++NV+AAW +GYTG  +VV+ILDDGIE+NHPDLA NYD  A
Sbjct: 117 KFPQQWYL-----SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171

Query: 224 SYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDV 283
           S+DVN  D DP PRY   N+N+HGTRCAGEVAA ANN  C VG+AYNA+IGG+RMLDG+V
Sbjct: 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231

Query: 284 TDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVW 343
           TD VEA+SLG+ PN+I IYSASWGP+DDGKTVDGP RLA++AF  G+ +GR GLGSIFVW
Sbjct: 232 TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291

Query: 344 ASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKI 403
           ASGNGGRE D C+CDGYTNSIYT+S+SSAT+ G  PWY E C+STLATTYSSG   E++I
Sbjct: 292 ASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351

Query: 404 VTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDW 463
           VTTDLRQ+CT+ HTGTS SAP+ AGIIAL LEAN  LTWRD+QHL+V+TS+PAHL A+DW
Sbjct: 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDW 411

Query: 464 KVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTA 523
             NG G KVSH YG+GL+DA A+V  A+ WT V  Q  C+      P+ I     +R T 
Sbjct: 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT- 470

Query: 524 LTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGF 583
             +AC    +  +  LEH   R ++S+ RRGDL I+LVSP GT+S LLA R  D S +GF
Sbjct: 471 -VTACLGEPN-HITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGF 528

Query: 584 TNWEFMTVHCWGEKAEGQWTLEIQD 608
            +W FMT H W E   G+W LEI++
Sbjct: 529 NDWAFMTTHSWDEDPSGEWVLEIEN 553


>gi|76443679 proprotein convertase subtilisin/kexin type 4 [Homo
           sapiens]
          Length = 755

 Score =  587 bits (1512), Expect = e-167
 Identities = 296/572 (51%), Positives = 385/572 (67%), Gaps = 20/572 (3%)

Query: 42  RPLAPRPW-RWLLLLAL--PAACSAPPPR-PVYTNHWAVQVLGGPAEADRVAAAHGYLNL 97
           RP     W R +L LAL  P A    P R P+Y + WAVQV  G  E +R+A   G++NL
Sbjct: 2   RPAPIALWLRLVLALALVRPRAVGWAPVRAPIYVSSWAVQVSQGNREVERLARKFGFVNL 61

Query: 98  GQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQA 157
           G I     Y+H  H    ++S     G    L+ +P+V+W QQQ ++RRVKR V      
Sbjct: 62  GPIFPDGQYFHLRHRGVVQQSLTPHWGHRLHLKKNPKVQWFQQQTLQRRVKRSV------ 115

Query: 158 LYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAP 217
           +   DP +S  WY+     NS  + ++++  AW +G +G+ +VV++LDDGIE++HPDL  
Sbjct: 116 VVPTDPWFSKQWYM-----NSEAQPDLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWA 170

Query: 218 NYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIR 277
           NYD  ASYD N  D DP PRY  S EN+HGTRCAGEVAA ANN +C VG+A+NA+IGG+R
Sbjct: 171 NYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVR 230

Query: 278 MLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGL 337
           MLDG +TDV+EA+SL ++P +I IYSASWGP+DDG+TVDGPG L ++AF  G+ KGR GL
Sbjct: 231 MLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGL 290

Query: 338 GSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGA 397
           G++F+WASGNGG   D C+CDGYTNSI+T+SV S T+ G  PWY E CASTL TTYSSG 
Sbjct: 291 GTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGV 350

Query: 398 FYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAH 457
             + +IVTTDL   CTD HTGTS SAP+ AG+IALALEAN  LTWRD+QHL+V+ S+PAH
Sbjct: 351 ATDPQIVTTDLHHGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAH 410

Query: 458 LKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQ 517
           L+A DW+ NG G +VSH YG+GL+DA  LV  A+ W     Q  C      RP   P++ 
Sbjct: 411 LQAEDWRTNGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQPQRKCAVRVQSRP--TPILP 468

Query: 518 VLRTTALTSACAE-HSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLL 576
           ++      SACA  H+  R   LEHV  + ++S+ RRGDL+I L SP GT+S L+A R L
Sbjct: 469 LIYIRENVSACAGLHNSIR--SLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPL 526

Query: 577 DLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQD 608
           D+S EG+ NW FM+ H W E  +G WTL +++
Sbjct: 527 DVSTEGYNNWVFMSTHFWDENPQGVWTLGLEN 558


>gi|20336242 proprotein convertase subtilisin/kexin type 1
           preproprotein [Homo sapiens]
          Length = 753

 Score =  583 bits (1502), Expect = e-166
 Identities = 296/570 (51%), Positives = 383/570 (67%), Gaps = 7/570 (1%)

Query: 51  WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
           ++L  A  A  SA   R  + N WA ++ GGP  A  +A   GY  LGQIG+LE++Y F 
Sbjct: 13  FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71

Query: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
           H    +RS  S+      L  D +V W +QQ  K R KR    D     FNDP+W+  WY
Sbjct: 72  HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131

Query: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
           L      +   + +++V   W++G TGK VV+T+LDDG+E NH D+  NYD  ASYD N 
Sbjct: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191

Query: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
           ND+DP PRYD +NENKHGTRCAGE+A  ANN  C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251

Query: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
            S+G  P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311

Query: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
           R+GD C CDGYT+SIYTIS+SSA++ G  PWY E+C+STLAT+YSSG + +++I + DL 
Sbjct: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371

Query: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
             CT+ HTGTS SAP+ AGI ALALEAN  LTWRD+QHL+V TS    L  +  WK NGA
Sbjct: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431

Query: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
           G  V+  +GFGL++A+ALV   + + W +VP +  CV   +D  PR++     +     T
Sbjct: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491

Query: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
            AC E  +  +  LEHV    +I + RRGDL + L S +GT + LLA+R  D S  GF N
Sbjct: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550

Query: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRN 615
           W+FM+VH WGE   G WTL I D+  +++N
Sbjct: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN 580


>gi|20336244 proprotein convertase subtilisin/kexin type 2 [Homo
           sapiens]
          Length = 638

 Score =  484 bits (1245), Expect = e-136
 Identities = 268/553 (48%), Positives = 346/553 (62%), Gaps = 12/553 (2%)

Query: 63  APPPRPVYTNHWAVQV-LGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLS 121
           A   RPV+TNH+ V++  GG  +A +VAA HG+  + ++   E  YHFYH+   K     
Sbjct: 23  ASAERPVFTNHFLVELHKGGEDKARQVAAEHGF-GVRKLPFAEGLYHFYHNGLAKAKRRR 81

Query: 122 SRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQA-LYFNDPIWSNMWYL-HCGDKNSR 179
           S      L  DP+VK   QQE   R KR  R   +  +  NDP+++  WYL + G  +  
Sbjct: 82  SLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGT 141

Query: 180 CRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYD 239
              ++NV  AW+ GYTGK V + I+DDGI+  HPDLA NY++ ASYD + ND  P PRY 
Sbjct: 142 PGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYT 201

Query: 240 ASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGD-VTDVVEAKSLGIRPNY 298
               N HGTRCAGEV+A+ANN+ C VG+AYN+K+ GIRMLD   +TD++EA S+   P  
Sbjct: 202 DDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQL 261

Query: 299 IDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCD 358
           IDIYSASWGP D+GKTVDGP  L  QA   G+ KGR G GSI+VWASG+GG   D C+CD
Sbjct: 262 IDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDD-CNCD 320

Query: 359 GYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFY--ERKIVTTDLRQRCTDGH 416
           GY +S++TIS++SA  +G    Y E C+STLA+T+S+G     E  + TTDL   CT  H
Sbjct: 321 GYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRH 380

Query: 417 TGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSR--PAHLKASDWKVNGAGHKVSH 474
           +GTS +AP  AG+ ALALEAN  LTWRD+QHL V TS+    H +   W+ NG G + +H
Sbjct: 381 SGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNH 440

Query: 475 FYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQ 534
            +G+G++DA A+V  AK W  VP +  CV  S + P  IP    L  T  T AC E  + 
Sbjct: 441 LFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDAC-EGKEN 499

Query: 535 RVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLL-DLSNEGFTNWEFMTVHC 593
            V YLEHV    +++  RRGDL I + SP GTKS LL++R   D S  GF  W FMT H 
Sbjct: 500 FVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHT 559

Query: 594 WGEKAEGQWTLEI 606
           WGE A G WTLE+
Sbjct: 560 WGEDARGTWTLEL 572


>gi|20336248 proprotein convertase subtilisin/kexin type 7
           preproprotein [Homo sapiens]
          Length = 785

 Score =  446 bits (1148), Expect = e-125
 Identities = 239/534 (44%), Positives = 317/534 (59%), Gaps = 19/534 (3%)

Query: 84  EADRVAAAHGYLNLGQIGNLEDYYHFY----HSKTFKRSTLSSRGPHTFLRMDPQVKWLQ 139
           +AD +A A G +N G+IG L+ +Y F     H    +   +  +     L     V+W  
Sbjct: 73  QADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQ-VEAVLAGHEAVRWHS 131

Query: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNV 199
           +Q + RR KR V       +FNDP +   W+L+      R   ++NV   W+R  TG+ V
Sbjct: 132 EQRLLRRAKRSV-------HFNDPKYPQQWHLNNRRSPGR---DINVTGVWERNVTGRGV 181

Query: 200 VVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASAN 259
            V ++DDG+E    D+APNY    SYD+N ND DP P  D  N N HGTRCAGE+AA  N
Sbjct: 182 TVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPN 241

Query: 260 NSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPG 319
           NS+C VG+AY ++I GIR+LDG +TD +EA +        DIYS SWGPDDDGKTVDGP 
Sbjct: 242 NSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPH 301

Query: 320 RLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKP 379
           +L K A ++G+  GRQG GSIFV ASGNGG+  D C+ DGY NSIYT+++ +  E G  P
Sbjct: 302 QLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMP 361

Query: 380 WYLEECASTLATTYSSGAFYERKIVTTDLRQR----CTDGHTGTSVSAPMVAGIIALALE 435
           +Y EECAS LA T+S G    R IVTTD   +    CT+GHTGTS +AP+ AG+IAL L+
Sbjct: 362 FYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQ 421

Query: 436 ANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTA 495
               LTWRDVQH++V T+     + ++W  N AG   SH +GFGL++A  LV  AK WT+
Sbjct: 422 VRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTS 481

Query: 496 VPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGD 555
           VP     V+   K  ++IP            +  +     +  LEHV V  SI+HPRRG 
Sbjct: 482 VPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGS 541

Query: 556 LQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDL 609
           L++ L  PSG  S + A R +D    GF +W F TV CWGE+A G + L I+D+
Sbjct: 542 LELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDV 595


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 33/73 (45%), Positives = 38/73 (52%), Gaps = 7/73 (9%)

Query: 2   PPRAPPAPGPRPPPRAAAATDTAAGA-GGAGGAGGAGGPGFRPL-----APRPWRWLLL- 54
           P  APP PGP PPP   ++  +A+   G  G  GGA  PG R L      PRP+  LLL 
Sbjct: 51  PSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLP 110

Query: 55  LALPAACSAPPPR 67
           LA P A  A P R
Sbjct: 111 LASPGAPPAAPTR 123


>gi|28269693 xylosyltransferase I [Homo sapiens]
          Length = 959

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 30/73 (41%), Positives = 33/73 (45%), Gaps = 7/73 (9%)

Query: 6   PPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFR-------PLAPRPWRWLLLLALP 58
           PPAP PR   R   A   AA  GG GG GG GG G +       P  PR  +     ALP
Sbjct: 58  PPAPAPRRERRDLPAEPAAARGGGGGGGGGGGGRGPQARARGGGPGEPRGQQPASRGALP 117

Query: 59  AACSAPPPRPVYT 71
           A    P P P+ T
Sbjct: 118 ARALDPHPSPLIT 130


>gi|4758392 forkhead box D1 [Homo sapiens]
          Length = 465

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 5/67 (7%)

Query: 5   APPAPG----PRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
           APPA G    P P P A A      G GGAGG G AG     PL   P+ ++ L+ + A 
Sbjct: 80  APPAGGSPAPPGPAPAAGAGAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITM-AI 138

Query: 61  CSAPPPR 67
             +P  R
Sbjct: 139 LQSPKKR 145



 Score = 30.0 bits (66), Expect = 7.0
 Identities = 20/43 (46%), Positives = 20/43 (46%), Gaps = 7/43 (16%)

Query: 11  PRPPPRAAAATDTAAGAGGAGGAGGAGGPG-----FRPLAPRP 48
           P  PP AAAA        GAG AGGAG P      F P  P P
Sbjct: 225 PLLPPNAAAAESLL--LRGAGAAGGAGDPAAAAALFPPAPPPP 265


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 36/99 (36%), Positives = 43/99 (43%), Gaps = 15/99 (15%)

Query: 7   PAPGPRPPPRAAAATDTAAGAG--------GAGGAGGAGGPGFRPLAPRP----WRWLLL 54
           P+PG   P +A  +  TA  +G        G GGAGG GG G+RP+   P     +    
Sbjct: 339 PSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGG-GYRPIIQSPGYKTGKGGYG 397

Query: 55  LALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHG 93
            A   A   PPPR   T     Q LGGPA A     A G
Sbjct: 398 AAAGGATRPPPPRSTATP--KCQSLGGPAAAYATGKASG 434



 Score = 33.1 bits (74), Expect = 0.83
 Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 9/45 (20%)

Query: 12  RPPPRAAAATDTAAGAGG---------AGGAGGAGGPGFRPLAPR 47
           RPPP  + AT      GG         A GAGGAGG  + P  P+
Sbjct: 405 RPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQ 449



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 2   PPRAPPAPGPRP--PPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPW 49
           PPR+   P  +    P AA AT  A+GAGGAGG   + G     L P+ +
Sbjct: 408 PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAY 457



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 16/82 (19%)

Query: 2   PPRAPPAPGPRPPPR---------------AAAATDTAAGAGGAGGAGGAGGPGFRPLAP 46
           PP  P  P P PPPR               AAAA  ++       GA     P  R L P
Sbjct: 225 PPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERAL-P 283

Query: 47  RPWRWLLLLALPAACSAPPPRP 68
           R    +     PA+   PPP P
Sbjct: 284 RQDTVIKHYQRPASAQPPPPPP 305



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 23/68 (33%), Positives = 26/68 (38%), Gaps = 10/68 (14%)

Query: 2    PPRAPPAPGPRP-PPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
            PP  PPAP P+P PP        A  +     A     P   PL P P         P A
Sbjct: 1458 PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP---------PPA 1508

Query: 61   CSAPPPRP 68
              +PPP P
Sbjct: 1509 MPSPPPPP 1516



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 8/60 (13%)

Query: 11  PRPPPRAAA--------ATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACS 62
           P PP  + A        A D + G GG+GGAGG  G  +      P R+ L   +  + S
Sbjct: 650 PSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSAS 709


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 15/73 (20%)

Query: 2   PPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAAC 61
           PPRAPP P P PPP     +   A  G A   G A  P   P +P P       A P++C
Sbjct: 785 PPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAP--IPRSPLP-------AGPSSC 835

Query: 62  SAP------PPRP 68
           ++P      PPRP
Sbjct: 836 TSPRSPLPAPPRP 848


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 27/64 (42%), Positives = 30/64 (46%), Gaps = 13/64 (20%)

Query: 5    APPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAP 64
            +PPAP   P     +      GAGGAGG GGAGG    P AP P R           +AP
Sbjct: 1054 SPPAPARWPRSDPESQPLLGPGAGGAGGTGGAGGGA--PAAPPPCR-----------AAP 1100

Query: 65   PPRP 68
            PP P
Sbjct: 1101 PPCP 1104



 Score = 33.1 bits (74), Expect = 0.83
 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 3   PRAPPAPGPRP-PPRAAAATDTAAGAGGAGGAGGAG-GPGFR----PLAPRPWRWLLLLA 56
           P   PAPGP P  PR  A+ D      GAG  GGAG   GF     P+ P+     L L 
Sbjct: 921 PAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLADGFHRYYGPIEPQG----LGLG 976

Query: 57  LPAACSAP 64
           L  A +AP
Sbjct: 977 LGEARAAP 984


>gi|87299628 biorientation of chromosomes in cell division 1-like
          [Homo sapiens]
          Length = 3051

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/39 (56%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 2  PPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAG-GAGGP 39
          PP  PP P P+PPP          GAGGAGGAG GAG P
Sbjct: 14 PPPPPPQPQPQPPP-PPPGPGAGPGAGGAGGAGAGAGDP 51



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 18/36 (50%), Positives = 20/36 (55%)

Query: 2  PPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAG 37
          PP APP P P+P P+            GAGGAGGAG
Sbjct: 10 PPPAPPPPPPQPQPQPPPPPPGPGAGPGAGGAGGAG 45


>gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo
           sapiens]
          Length = 304

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 30/105 (28%)

Query: 6   PPAPGPRPP-------PRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALP 58
           P  P PRPP       PR  A  +   G  GAGG GGA     + + PRP R L+     
Sbjct: 210 PTPPRPRPPGLRSGDVPRGGARVERPTGRRGAGGRGGA-----QRIPPRPLRRLV----- 259

Query: 59  AACSAPPPRPVYTNHWA--VQVLGGPAEA----DRVAAAHGYLNL 97
                  P   + +HW+   ++L G A A    +R+ AAH Y ++
Sbjct: 260 -------PIHPHPSHWSFCTRLLEGWAPAVTHSERLVAAHTYTHI 297


>gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo
           sapiens]
          Length = 304

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 30/105 (28%)

Query: 6   PPAPGPRPP-------PRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALP 58
           P  P PRPP       PR  A  +   G  GAGG GGA     + + PRP R L+     
Sbjct: 210 PTPPRPRPPGLRSGDVPRGGARVERPTGRRGAGGRGGA-----QRIPPRPLRRLV----- 259

Query: 59  AACSAPPPRPVYTNHWA--VQVLGGPAEA----DRVAAAHGYLNL 97
                  P   + +HW+   ++L G A A    +R+ AAH Y ++
Sbjct: 260 -------PIHPHPSHWSFCTRLLEGWAPAVTHSERLVAAHTYTHI 297


>gi|32171221 GRP1 (general receptor for phosphoinositides
           1)-associated scaffold protein [Homo sapiens]
          Length = 395

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 18/38 (47%), Positives = 20/38 (52%)

Query: 3   PRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPG 40
           P   PA GP P PRAA +   +    G GG GG G PG
Sbjct: 312 PAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPG 349


>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
          Length = 492

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 22/43 (51%), Positives = 23/43 (53%), Gaps = 6/43 (13%)

Query: 3   PRAPPAPGPRPPPRA------AAATDTAAGAGGAGGAGGAGGP 39
           P    AP P PPP A      AAA +   GAG  GGAGG GGP
Sbjct: 338 PAGGAAPPPPPPPGALGSFALAAAANGYLGAGAGGGAGGGGGP 380



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 27/87 (31%), Positives = 31/87 (35%), Gaps = 32/87 (36%)

Query: 15  PRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAPPPRPVYTNHW 74
           P AAAA +  A   G  GAG AGG                     A   PPP P     +
Sbjct: 318 PAAAAAANLLASYAGEAGAGPAGG---------------------AAPPPPPPPGALGSF 356

Query: 75  AVQVLGGPAEADRVAAAHGYLNLGQIG 101
           A+            AAA+GYL  G  G
Sbjct: 357 AL-----------AAAANGYLGAGAGG 372


>gi|5454106 TBP-related factor 10 [Homo sapiens]
          Length = 218

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 40/115 (34%), Positives = 47/115 (40%), Gaps = 12/115 (10%)

Query: 2   PPRAPPAPGPRPP-------PRAAAATDTAAGAGGAGGAG-GAGGPGFRPLAPRPWRWLL 53
           P  A  APGP PP       P + AA + A+ AG AGG G GA   G  PLA R      
Sbjct: 14  PASAASAPGPAPPVSAPAALPSSTAAENKASPAGTAGGPGAGAAAGGTGPLAARAGEPAE 73

Query: 54  L--LALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDY 106
               A  +A  A PP    +N   V VL   A  D          +  +  LEDY
Sbjct: 74  RRGAAPVSAGGAAPPEGAISN--GVYVLPSAANGDVKPVVSSTPLVDFLMQLEDY 126


>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
          Length = 2778

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 22/42 (52%), Positives = 23/42 (54%), Gaps = 5/42 (11%)

Query: 6    PPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPR 47
            PPAP P PPP    A     GAG  GGAG + GPG  P  PR
Sbjct: 2462 PPAPPPPPPP----ADGGPRGAGDPGGAGASSGPG-APAEPR 2498


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 7/67 (10%)

Query: 2   PPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAAC 61
           PP A  AP P PPP    A+  A  +G     G A GPG    AP P       AL A  
Sbjct: 75  PPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTP-------ALVAGS 127

Query: 62  SAPPPRP 68
           SA  P P
Sbjct: 128 SAAAPFP 134



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 12/72 (16%)

Query: 2  PPRAPPAPG-----PRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLA 56
          PP A  AP      P PP  +A ++   +  GGAGG G         L P P        
Sbjct: 22 PPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPP-------P 74

Query: 57 LPAACSAPPPRP 68
           P A +APPP P
Sbjct: 75 PPPATAAPPPPP 86


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 22/54 (40%), Positives = 23/54 (42%), Gaps = 8/54 (14%)

Query: 3   PRAPPAPGPRPPPRAAAATDTAAGA--------GGAGGAGGAGGPGFRPLAPRP 48
           P  PP   P  PP AAA    +AGA        GG  G  G  GPG    AP P
Sbjct: 287 PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 34/104 (32%), Positives = 37/104 (35%), Gaps = 16/104 (15%)

Query: 2   PPRAPPAPG--------PRPPPRAAAATDTAAGA--GGAGGAG-----GAGGPGFRPLAP 46
           PP  PPAP         P  PP AA A    A A  GG+ GA       AGGP      P
Sbjct: 270 PPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP 329

Query: 47  RPWRWLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAA 90
            P       A P   +  P R V     A Q L     A   A+
Sbjct: 330 GPGAAAAAPA-PGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 17/42 (40%), Positives = 18/42 (42%)

Query: 5   APPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP 46
           A P P P  P + A     AA AG   G G   GPG  P  P
Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP 189



 Score = 29.6 bits (65), Expect = 9.1
 Identities = 22/64 (34%), Positives = 24/64 (37%), Gaps = 1/64 (1%)

Query: 5   APPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAP 64
           APPA   RPPP  +A +     A  A  AG    P   P  P     L   A P     P
Sbjct: 120 APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA-GPAKPAGPAALAARAGPGPGPGP 178

Query: 65  PPRP 68
            P P
Sbjct: 179 GPGP 182


>gi|82546824 forkhead box K1 [Homo sapiens]
          Length = 733

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 19/41 (46%), Positives = 21/41 (51%), Gaps = 4/41 (9%)

Query: 2  PPRAP----PAPGPRPPPRAAAATDTAAGAGGAGGAGGAGG 38
          PP AP    P PGP PPP         AGAG +GG+ G  G
Sbjct: 39 PPPAPAQPQPPPGPPPPPPPPLPPGAIAGAGSSGGSSGVSG 79


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,485,457
Number of Sequences: 37866
Number of extensions: 1566094
Number of successful extensions: 21178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 283
Number of HSP's that attempted gapping in prelim test: 15701
Number of HSP's gapped (non-prelim): 4394
length of query: 652
length of database: 18,247,518
effective HSP length: 109
effective length of query: 543
effective length of database: 14,120,124
effective search space: 7667227332
effective search space used: 7667227332
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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