Guide to the Human Genome
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Name: PCSK2 Sequence: fasta or formatted (638aa) NCBI GI: 20336244
Description:

proprotein convertase subtilisin/kexin type 2

Referenced in:

Peptide-processing Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.5         54           3
 C cysteine            1.6         10           1
 D aspartate           6.9         44           3
 E glutamate           5.5         35           3
 F phenylalanine       3.4         22           1
 G glycine             9.6         61           2
 H histidine           3.0         19           2
 I isoleucine          3.8         24           2
 K lysine              5.5         35           2
 L leucine             8.0         51           2
 M methionine          2.8         18           1
 N asparagine          5.2         33           3
 P proline             3.6         23           1
 Q glutamine           3.1         20           2
 R arginine            5.3         34           3
 S serine              6.6         42           2
 T threonine           6.1         39           2
 V valine              6.0         38           2
 W tryptophan          2.2         14           1
 Y tyrosine            3.4         22           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   proprotein convertase subtilisin/kexin type 2 
PCSK1                 0.379   proprotein convertase subtilisin/kexin type 1 prepro...
FURIN                 0.379   furin preproprotein 
PCSK6                 0.370   paired basic amino acid cleaving system 4 isoform h ...
PCSK6                 0.370   paired basic amino acid cleaving system 4 isoform g ...
PCSK6                 0.370   paired basic amino acid cleaving system 4 isoform a p...
PCSK6                 0.370   paired basic amino acid cleaving system 4 isoform b ...
PCSK4                 0.356   proprotein convertase subtilisin/kexin type 4 
PCSK6                 0.355   paired basic amino acid cleaving system 4 isoform e ...
PCSK6                 0.355   paired basic amino acid cleaving system 4 isoform f ...
PCSK6                 0.355   paired basic amino acid cleaving system 4 isoform d ...
PCSK5                 0.350   proprotein convertase subtilisin/kexin type 5 prepro...
PCSK7                 0.272   proprotein convertase subtilisin/kexin type 7 prepro...
PCSK6                 0.268   paired basic amino acid cleaving system 4 isoform c ...
MBTPS1                0.009   membrane-bound transcription factor site-1 protease p...
SF3A3                 0.009   splicing factor 3a, subunit 3 
CDH9                  0.006   cadherin 9, type 2 preproprotein 
AKAP13                0.005   A-kinase anchor protein 13 isoform 1 
AKAP13                0.005   A-kinase anchor protein 13 isoform 3 
AKAP13                0.005   A-kinase anchor protein 13 isoform 2 
DCHS1                 0.005   dachsous 1 precursor 
LOC100292407          0.005   PREDICTED: hypothetical protein 
PLOD2                 0.004   procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 i...
PLOD2                 0.004   procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 i...
PCSK9                 0.004   proprotein convertase subtilisin/kexin type 9 prepro...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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