Guide to the Human Genome
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Name: FURIN Sequence: fasta or formatted (794aa) NCBI GI: 4505579
Description:

furin preproprotein

Referenced in:

Peptide-processing Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.8         70           2
 C cysteine            2.8         22           1
 D aspartate           5.2         41           2
 E glutamate           5.4         43           2
 F phenylalanine       2.6         21           2
 G glycine             8.4         67           2
 H histidine           3.3         26           1
 I isoleucine          3.1         25           2
 K lysine              3.0         24           1
 L leucine             8.3         66           2
 M methionine          1.0          8           1
 N asparagine          4.2         33           2
 P proline             6.0         48           2
 Q glutamine           5.2         41           3
 R arginine            5.8         46           2
 S serine              7.7         61           2
 T threonine           6.9         55           2
 V valine              7.3         58           2
 W tryptophan          2.1         17           1
 Y tyrosine            2.8         22           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   furin preproprotein 
PCSK4                 0.467   proprotein convertase subtilisin/kexin type 4 
PCSK5                 0.400   proprotein convertase subtilisin/kexin type 5 prepro...
PCSK6                 0.399   paired basic amino acid cleaving system 4 isoform h ...
PCSK6                 0.399   paired basic amino acid cleaving system 4 isoform b ...
PCSK6                 0.397   paired basic amino acid cleaving system 4 isoform g ...
PCSK6                 0.397   paired basic amino acid cleaving system 4 isoform a p...
PCSK6                 0.384   paired basic amino acid cleaving system 4 isoform e ...
PCSK6                 0.384   paired basic amino acid cleaving system 4 isoform f ...
PCSK6                 0.384   paired basic amino acid cleaving system 4 isoform d ...
PCSK1                 0.341   proprotein convertase subtilisin/kexin type 1 prepro...
PCSK6                 0.315   paired basic amino acid cleaving system 4 isoform c ...
PCSK2                 0.302   proprotein convertase subtilisin/kexin type 2 
PCSK7                 0.248   proprotein convertase subtilisin/kexin type 7 prepro...
LOC100292811          0.018   PREDICTED: similar to proprotein convertase subtili...
LOC100290671          0.018   PREDICTED: hypothetical protein XP_002347099 
LOC100289618          0.017   PREDICTED: hypothetical protein XP_002342982 
FRAS1                 0.014   Fraser syndrome 1 
RSPO2                 0.009   R-spondin family, member 2 
ERBB3                 0.007   erbB-3 isoform 1 precursor 
RSPO3                 0.007   R-spondin 3 
MEGF11                0.007   multiple EGF-like-domains 11 
CRELD2                0.006   cysteine-rich with EGF-like domains 2 isoform b [Ho...
CRELD2                0.006   cysteine-rich with EGF-like domains 2 isoform a [Ho...
MEGF6                 0.006   EGF-like-domain, multiple 3 
THSD7B                0.006   thrombospondin, type I, domain containing 7B 
TNFRSF1B              0.006   tumor necrosis factor receptor 2 precursor 
BAP1                  0.006   BRCA1 associated protein-1 
ERBB4                 0.005   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.005   v-erb-a erythroblastic leukemia viral oncogene homolo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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