Guide to the Human Genome
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Name: PCSK5 Sequence: fasta or formatted (913aa) NCBI GI: 20336246
Description:

proprotein convertase subtilisin/kexin type 5 preproprotein

Referenced in:

Peptide-processing Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         55           4
 C cysteine            6.8         62           3
 D aspartate           6.2         57           3
 E glutamate           4.7         43           2
 F phenylalanine       3.2         29           1
 G glycine             8.4         77           2
 H histidine           3.4         31           1
 I isoleucine          3.9         36           2
 K lysine              5.4         49           2
 L leucine             5.5         50           2
 M methionine          2.3         21           1
 N asparagine          5.3         48           2
 P proline             4.3         39           2
 Q glutamine           3.0         27           3
 R arginine            5.6         51           2
 S serine              8.2         75           2
 T threonine           6.4         58           2
 V valine              5.3         48           3
 W tryptophan          1.9         17           1
 Y tyrosine            4.4         40           3
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   proprotein convertase subtilisin/kexin type 5 prepro... 
PCSK6                 0.553   paired basic amino acid cleaving system 4 isoform b ...
PCSK6                 0.547   paired basic amino acid cleaving system 4 isoform a p...
PCSK6                 0.523   paired basic amino acid cleaving system 4 isoform h ...
PCSK6                 0.518   paired basic amino acid cleaving system 4 isoform g ...
PCSK6                 0.416   paired basic amino acid cleaving system 4 isoform e ...
PCSK6                 0.416   paired basic amino acid cleaving system 4 isoform f ...
PCSK6                 0.416   paired basic amino acid cleaving system 4 isoform d ...
FURIN                 0.332   furin preproprotein 
PCSK6                 0.318   paired basic amino acid cleaving system 4 isoform c ...
PCSK4                 0.299   proprotein convertase subtilisin/kexin type 4 
PCSK1                 0.282   proprotein convertase subtilisin/kexin type 1 prepro...
PCSK2                 0.232   proprotein convertase subtilisin/kexin type 2 
PCSK7                 0.222   proprotein convertase subtilisin/kexin type 7 prepro...
LOC100292811          0.067   PREDICTED: similar to proprotein convertase subtili...
LOC100290671          0.067   PREDICTED: hypothetical protein XP_002347099 
LOC100289618          0.067   PREDICTED: hypothetical protein XP_002342982 
FRAS1                 0.058   Fraser syndrome 1 
CRELD2                0.029   cysteine-rich with EGF-like domains 2 isoform b [Ho...
CRELD2                0.026   cysteine-rich with EGF-like domains 2 isoform a [Ho...
MEGF11                0.023   multiple EGF-like-domains 11 
ERBB3                 0.022   erbB-3 isoform 1 precursor 
ERBB4                 0.019   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.019   v-erb-a erythroblastic leukemia viral oncogene homolo...
RSPO1                 0.018   R-spondin1 
MEGF9                 0.017   multiple EGF-like-domains 9 
ERBB2                 0.017   erbB-2 isoform b 
ERBB2                 0.017   erbB-2 isoform a 
LAMB4                 0.016   laminin, beta 4 
MATN2                 0.016   matrilin 2 isoform b precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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