Guide to the Human Genome
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Name: PCSK1 Sequence: fasta or formatted (753aa) NCBI GI: 20336242
Description:

proprotein convertase subtilisin/kexin type 1 preproprotein

Referenced in:

Peptide-processing Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.0         60           2
 C cysteine            1.5         11           1
 D aspartate           6.6         50           3
 E glutamate           6.6         50           2
 F phenylalanine       2.8         21           1
 G glycine             7.3         55           2
 H histidine           2.5         19           1
 I isoleucine          4.4         33           2
 K lysine              5.6         42           2
 L leucine             7.6         57           2
 M methionine          1.6         12           1
 N asparagine          6.4         48           2
 P proline             5.0         38           2
 Q glutamine           4.1         31           2
 R arginine            5.4         41           2
 S serine              8.1         61           4
 T threonine           5.4         41           1
 V valine              5.0         38           2
 W tryptophan          2.5         19           1
 Y tyrosine            3.5         26           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   proprotein convertase subtilisin/kexin type 1 prepro... 
PCSK6                 0.375   paired basic amino acid cleaving system 4 isoform h ...
PCSK6                 0.375   paired basic amino acid cleaving system 4 isoform g ...
PCSK6                 0.375   paired basic amino acid cleaving system 4 isoform a p...
PCSK6                 0.375   paired basic amino acid cleaving system 4 isoform b ...
PCSK6                 0.364   paired basic amino acid cleaving system 4 isoform e ...
PCSK6                 0.364   paired basic amino acid cleaving system 4 isoform f ...
PCSK6                 0.364   paired basic amino acid cleaving system 4 isoform d ...
FURIN                 0.360   furin preproprotein 
PCSK5                 0.358   proprotein convertase subtilisin/kexin type 5 prepro...
PCSK4                 0.342   proprotein convertase subtilisin/kexin type 4 
PCSK2                 0.320   proprotein convertase subtilisin/kexin type 2 
PCSK6                 0.297   paired basic amino acid cleaving system 4 isoform c ...
PCSK7                 0.261   proprotein convertase subtilisin/kexin type 7 prepro...
MBTPS1                0.008   membrane-bound transcription factor site-1 protease p...
BTBD12                0.007   BTB (POZ) domain containing 12 
USP6                  0.007   ubiquitin specific protease 6 
NCOR2                 0.005   nuclear receptor co-repressor 2 isoform 2 
NCOR2                 0.005   nuclear receptor co-repressor 2 isoform 1 
PCSK9                 0.005   proprotein convertase subtilisin/kexin type 9 prepro...
ZHX3                  0.005   zinc fingers and homeoboxes 3 
ZBTB44                0.005   zinc finger and BTB domain containing 44 
ZNF853                0.005   zinc finger protein 853 
CCNL2                 0.005   cyclin L2 isoform A 
BPTF                  0.005   bromodomain PHD finger transcription factor isoform ...
UMODL1                0.005   uromodulin-like 1 isoform 2 precursor 
MAGEC1                0.004   melanoma antigen family C, 1 
CD300LG               0.004   CD300 molecule-like family member g 
KIAA1486              0.003   hypothetical protein LOC57624 
LOC100293817          0.003   PREDICTED: similar to hCG1811893 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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