Guide to the Human Genome
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Name: PCSK6 Sequence: fasta or formatted (956aa) NCBI GI: 20336180
Description:

paired basic amino acid cleaving system 4 isoform b preproprotein

Referenced in:

Peptide-processing Enzymes

Other entries for this name:
alt prot [975aa] paired basic amino acid cleaving system 4 isoform g preproprotein
alt prot [962aa] paired basic amino acid cleaving system 4 isoform h preproprotein
alt prot [487aa] paired basic amino acid cleaving system 4 isoform c preproprotein
alt prot [623aa] paired basic amino acid cleaving system 4 isoform e preproprotein
alt prot [652aa] paired basic amino acid cleaving system 4 isoform d preproprotein
alt prot [664aa] paired basic amino acid cleaving system 4 isoform f preproprotein
alt prot [969aa] paired basic amino acid cleaving system 4 isoform a preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.5         81           4
 C cysteine            5.9         56           2
 D aspartate           5.0         48           3
 E glutamate           5.5         53           2
 F phenylalanine       2.7         26           1
 G glycine             8.6         82           2
 H histidine           3.6         34           2
 I isoleucine          2.9         28           2
 K lysine              4.9         47           2
 L leucine             7.0         67           4
 M methionine          1.3         12           1
 N asparagine          3.8         36           2
 P proline             6.2         59           3
 Q glutamine           3.2         31           3
 R arginine            6.3         60           2
 S serine              7.5         72           2
 T threonine           5.5         53           2
 V valine              6.0         57           3
 W tryptophan          1.9         18           1
 Y tyrosine            3.8         36           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   paired basic amino acid cleaving system 4 isoform b ... 
PCSK6                 0.995   paired basic amino acid cleaving system 4 isoform a p...
PCSK6                 0.925   paired basic amino acid cleaving system 4 isoform h ...
PCSK6                 0.920   paired basic amino acid cleaving system 4 isoform g ...
PCSK6                 0.629   paired basic amino acid cleaving system 4 isoform e ...
PCSK6                 0.629   paired basic amino acid cleaving system 4 isoform f ...
PCSK6                 0.629   paired basic amino acid cleaving system 4 isoform d ...
PCSK5                 0.534   proprotein convertase subtilisin/kexin type 5 prepro...
PCSK6                 0.479   paired basic amino acid cleaving system 4 isoform c ...
FURIN                 0.321   furin preproprotein 
PCSK4                 0.293   proprotein convertase subtilisin/kexin type 4 
PCSK1                 0.285   proprotein convertase subtilisin/kexin type 1 prepro...
PCSK2                 0.237   proprotein convertase subtilisin/kexin type 2 
PCSK7                 0.216   proprotein convertase subtilisin/kexin type 7 prepro...
LOC100292811          0.058   PREDICTED: similar to proprotein convertase subtili...
LOC100290671          0.058   PREDICTED: hypothetical protein XP_002347099 
LOC100289618          0.058   PREDICTED: hypothetical protein XP_002342982 
FRAS1                 0.052   Fraser syndrome 1 
CRELD1                0.021   cysteine-rich with EGF-like domains 1 isoform 3 [Ho...
CRELD1                0.021   cysteine-rich with EGF-like domains 1 isoform 1 [Hom...
CRELD1                0.021   cysteine-rich with EGF-like domains 1 isoform 2 [Hom...
RSPO3                 0.020   R-spondin 3 
ERBB2                 0.019   erbB-2 isoform b 
ERBB2                 0.019   erbB-2 isoform a 
SCARF2                0.019   scavenger receptor class F, member 2 isoform 1 [Homo...
SCARF2                0.019   scavenger receptor class F, member 2 isoform 2 [Homo...
ERBB4                 0.018   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.018   v-erb-a erythroblastic leukemia viral oncogene homolo...
CRELD2                0.018   cysteine-rich with EGF-like domains 2 isoform b [Ho...
EGFR                  0.018   epidermal growth factor receptor isoform a precursor...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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