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Search of human proteins with 20336188
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20336188 paired basic amino acid cleaving system 4 isoform e
preproprotein [Homo sapiens]
(623 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20336188 paired basic amino acid cleaving system 4 isoform e ... 1299 0.0
gi|27894285 paired basic amino acid cleaving system 4 isoform f ... 1295 0.0
gi|20336190 paired basic amino acid cleaving system 4 isoform d ... 1295 0.0
gi|20336184 paired basic amino acid cleaving system 4 isoform h ... 1294 0.0
gi|20336182 paired basic amino acid cleaving system 4 isoform g ... 1294 0.0
gi|4505577 paired basic amino acid cleaving system 4 isoform a p... 1294 0.0
gi|20336180 paired basic amino acid cleaving system 4 isoform b ... 1294 0.0
gi|20336186 paired basic amino acid cleaving system 4 isoform c ... 992 0.0
gi|20336246 proprotein convertase subtilisin/kexin type 5 prepro... 835 0.0
gi|4505579 furin preproprotein [Homo sapiens] 647 0.0
gi|76443679 proprotein convertase subtilisin/kexin type 4 [Homo ... 587 e-167
gi|20336242 proprotein convertase subtilisin/kexin type 1 prepro... 583 e-166
gi|20336244 proprotein convertase subtilisin/kexin type 2 [Homo ... 484 e-136
gi|20336248 proprotein convertase subtilisin/kexin type 7 prepro... 446 e-125
gi|171543895 ataxin 2 [Homo sapiens] 49 2e-05
gi|28269693 xylosyltransferase I [Homo sapiens] 46 1e-04
gi|4758392 forkhead box D1 [Homo sapiens] 45 2e-04
gi|153792074 proline rich 12 [Homo sapiens] 45 2e-04
gi|40353727 synaptopodin isoform A [Homo sapiens] 43 8e-04
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 42 0.001
gi|87299628 biorientation of chromosomes in cell division 1-like... 42 0.001
gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo ... 42 0.002
gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo ... 42 0.002
gi|32171221 GRP1 (general receptor for phosphoinositides 1)-asso... 41 0.003
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 41 0.004
gi|5454106 TBP-related factor 10 [Homo sapiens] 40 0.006
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 40 0.006
gi|39812378 RAN binding protein 9 [Homo sapiens] 39 0.011
gi|110832843 TBP-associated factor 4 [Homo sapiens] 39 0.011
gi|82546824 forkhead box K1 [Homo sapiens] 39 0.011
>gi|20336188 paired basic amino acid cleaving system 4 isoform e
preproprotein [Homo sapiens]
Length = 623
Score = 1299 bits (3361), Expect = 0.0
Identities = 623/623 (100%), Positives = 623/623 (100%)
Query: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
Query: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
Query: 601 QWTLEIQDLPSQVRNPEKQGNLD 623
QWTLEIQDLPSQVRNPEKQGNLD
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGNLD 623
>gi|27894285 paired basic amino acid cleaving system 4 isoform f
preproprotein [Homo sapiens]
Length = 664
Score = 1295 bits (3352), Expect = 0.0
Identities = 621/623 (99%), Positives = 623/623 (100%)
Query: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
Query: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
Query: 601 QWTLEIQDLPSQVRNPEKQGNLD 623
QWTLEIQDLPSQVRNPEKQG+L+
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGDLE 623
>gi|20336190 paired basic amino acid cleaving system 4 isoform d
preproprotein [Homo sapiens]
Length = 652
Score = 1295 bits (3352), Expect = 0.0
Identities = 621/623 (99%), Positives = 623/623 (100%)
Query: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
Query: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
Query: 601 QWTLEIQDLPSQVRNPEKQGNLD 623
QWTLEIQDLPSQVRNPEKQG+L+
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGDLE 623
>gi|20336184 paired basic amino acid cleaving system 4 isoform h
preproprotein [Homo sapiens]
Length = 962
Score = 1294 bits (3349), Expect = 0.0
Identities = 621/622 (99%), Positives = 621/622 (99%)
Query: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
Query: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
Query: 601 QWTLEIQDLPSQVRNPEKQGNL 622
QWTLEIQDLPSQVRNPEKQG L
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGKL 622
>gi|20336182 paired basic amino acid cleaving system 4 isoform g
preproprotein [Homo sapiens]
Length = 975
Score = 1294 bits (3349), Expect = 0.0
Identities = 621/622 (99%), Positives = 621/622 (99%)
Query: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
Query: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
Query: 601 QWTLEIQDLPSQVRNPEKQGNL 622
QWTLEIQDLPSQVRNPEKQG L
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGKL 622
>gi|4505577 paired basic amino acid cleaving system 4 isoform a
preproprotein [Homo sapiens]
Length = 969
Score = 1294 bits (3349), Expect = 0.0
Identities = 621/622 (99%), Positives = 621/622 (99%)
Query: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
Query: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
Query: 601 QWTLEIQDLPSQVRNPEKQGNL 622
QWTLEIQDLPSQVRNPEKQG L
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGKL 622
>gi|20336180 paired basic amino acid cleaving system 4 isoform b
preproprotein [Homo sapiens]
Length = 956
Score = 1294 bits (3349), Expect = 0.0
Identities = 621/622 (99%), Positives = 621/622 (99%)
Query: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
Query: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL 480
Query: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
Sbjct: 481 VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE 540
Query: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
Sbjct: 541 HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG 600
Query: 601 QWTLEIQDLPSQVRNPEKQGNL 622
QWTLEIQDLPSQVRNPEKQG L
Sbjct: 601 QWTLEIQDLPSQVRNPEKQGKL 622
>gi|20336186 paired basic amino acid cleaving system 4 isoform c
preproprotein [Homo sapiens]
Length = 487
Score = 992 bits (2564), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
Sbjct: 1 MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
Query: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
Sbjct: 61 CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL 120
Query: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
Sbjct: 121 SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC 180
Query: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
Sbjct: 181 RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA 240
Query: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
Sbjct: 241 SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID 300
Query: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
Sbjct: 301 IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY 360
Query: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
Sbjct: 361 TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS 420
Query: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHK 471
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHK
Sbjct: 421 VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHK 471
>gi|20336246 proprotein convertase subtilisin/kexin type 5
preproprotein [Homo sapiens]
Length = 913
Score = 835 bits (2158), Expect = 0.0
Identities = 391/587 (66%), Positives = 470/587 (80%), Gaps = 2/587 (0%)
Query: 38 GPGFRPLAPRPWRWLLLLALPAACSAPPPRP-VYTNHWAVQVLGGPAEADRVAAAHGYLN 96
G G R P L +LAL C P R VYTNHWAV++ GG EA+R+A+ +G++N
Sbjct: 2 GWGSRCCCPGRLDLLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYGFIN 61
Query: 97 LGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVR-SDP 155
+GQIG L+DYYHFYHS+T KRS +SSRG H+F+ M+P+V+W+QQQ VK+R KR S
Sbjct: 62 IGQIGALKDYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRA 121
Query: 156 QALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDL 215
Q+ YFNDP W +MWY+HC D C+S+MN++ AWKRGYTGKN+VVTILDDGIER HPDL
Sbjct: 122 QSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDL 181
Query: 216 APNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGG 275
NYD+ AS DVNGND DP PRYDASNENKHGTRCAGEVAA+ANNS+C VGIA+NAKIGG
Sbjct: 182 MQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGG 241
Query: 276 IRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQ 335
+RMLDGDVTD+VEAKS+ P ++ IYSASWGPDDDGKTVDGP L +QAFE G++ GR+
Sbjct: 242 VRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRR 301
Query: 336 GLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSS 395
GLGS+FVWASGNGGR D+CSCDGYTNSIYTIS+SS E+G KPWYLEEC+STLATTYSS
Sbjct: 302 GLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSS 361
Query: 396 GAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRP 455
G Y++KI+TTDLRQRCTD HTGTS SAPM AGIIALALEAN LTWRDVQH++V+TSR
Sbjct: 362 GESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRA 421
Query: 456 AHLKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPL 515
HL A+DWK N AG KVSH YGFGL+DAEA+V+EA+KWT VP QH+CV ++D++ ++I
Sbjct: 422 GHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRP 481
Query: 516 VQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRL 575
+R+ S C+++ ++ V YLEHVVVR +I+HPRRGDL IYL SPSGT+SQLLA RL
Sbjct: 482 NSAVRSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRL 541
Query: 576 LDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGNL 622
D S EGF NWEFMT+HCWGE+A G W LE+ D PSQ+RN + G L
Sbjct: 542 FDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKL 588
>gi|4505579 furin preproprotein [Homo sapiens]
Length = 794
Score = 647 bits (1668), Expect = 0.0
Identities = 324/565 (57%), Positives = 400/565 (70%), Gaps = 18/565 (3%)
Query: 47 RPWRWLLLLA---LPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNL 103
RPW ++ A L + + V+TN WAV++ GGPA A+ VA HG+LNLGQI
Sbjct: 4 RPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--F 61
Query: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDP 163
DYYHF+H KRS R H+ L+ +PQV+WL+QQ KRR KR V +P DP
Sbjct: 62 GDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP-----TDP 116
Query: 164 IWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYA 223
+ WYL + + ++NV+AAW +GYTG +VV+ILDDGIE+NHPDLA NYD A
Sbjct: 117 KFPQQWYL-----SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
Query: 224 SYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDV 283
S+DVN D DP PRY N+N+HGTRCAGEVAA ANN C VG+AYNA+IGG+RMLDG+V
Sbjct: 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
Query: 284 TDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVW 343
TD VEA+SLG+ PN+I IYSASWGP+DDGKTVDGP RLA++AF G+ +GR GLGSIFVW
Sbjct: 232 TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291
Query: 344 ASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKI 403
ASGNGGRE D C+CDGYTNSIYT+S+SSAT+ G PWY E C+STLATTYSSG E++I
Sbjct: 292 ASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
Query: 404 VTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDW 463
VTTDLRQ+CT+ HTGTS SAP+ AGIIAL LEAN LTWRD+QHL+V+TS+PAHL A+DW
Sbjct: 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDW 411
Query: 464 KVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTA 523
NG G KVSH YG+GL+DA A+V A+ WT V Q C+ P+ I +R T
Sbjct: 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT- 470
Query: 524 LTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGF 583
+AC + + LEH R ++S+ RRGDL I+LVSP GT+S LLA R D S +GF
Sbjct: 471 -VTACLGEPN-HITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGF 528
Query: 584 TNWEFMTVHCWGEKAEGQWTLEIQD 608
+W FMT H W E G+W LEI++
Sbjct: 529 NDWAFMTTHSWDEDPSGEWVLEIEN 553
>gi|76443679 proprotein convertase subtilisin/kexin type 4 [Homo
sapiens]
Length = 755
Score = 587 bits (1512), Expect = e-167
Identities = 296/572 (51%), Positives = 385/572 (67%), Gaps = 20/572 (3%)
Query: 42 RPLAPRPW-RWLLLLAL--PAACSAPPPR-PVYTNHWAVQVLGGPAEADRVAAAHGYLNL 97
RP W R +L LAL P A P R P+Y + WAVQV G E +R+A G++NL
Sbjct: 2 RPAPIALWLRLVLALALVRPRAVGWAPVRAPIYVSSWAVQVSQGNREVERLARKFGFVNL 61
Query: 98 GQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQA 157
G I Y+H H ++S G L+ +P+V+W QQQ ++RRVKR V
Sbjct: 62 GPIFPDGQYFHLRHRGVVQQSLTPHWGHRLHLKKNPKVQWFQQQTLQRRVKRSV------ 115
Query: 158 LYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAP 217
+ DP +S WY+ NS + ++++ AW +G +G+ +VV++LDDGIE++HPDL
Sbjct: 116 VVPTDPWFSKQWYM-----NSEAQPDLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWA 170
Query: 218 NYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIR 277
NYD ASYD N D DP PRY S EN+HGTRCAGEVAA ANN +C VG+A+NA+IGG+R
Sbjct: 171 NYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVR 230
Query: 278 MLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGL 337
MLDG +TDV+EA+SL ++P +I IYSASWGP+DDG+TVDGPG L ++AF G+ KGR GL
Sbjct: 231 MLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGL 290
Query: 338 GSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGA 397
G++F+WASGNGG D C+CDGYTNSI+T+SV S T+ G PWY E CASTL TTYSSG
Sbjct: 291 GTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGV 350
Query: 398 FYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAH 457
+ +IVTTDL CTD HTGTS SAP+ AG+IALALEAN LTWRD+QHL+V+ S+PAH
Sbjct: 351 ATDPQIVTTDLHHGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAH 410
Query: 458 LKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQ 517
L+A DW+ NG G +VSH YG+GL+DA LV A+ W Q C RP P++
Sbjct: 411 LQAEDWRTNGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQPQRKCAVRVQSRP--TPILP 468
Query: 518 VLRTTALTSACAE-HSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLL 576
++ SACA H+ R LEHV + ++S+ RRGDL+I L SP GT+S L+A R L
Sbjct: 469 LIYIRENVSACAGLHNSIR--SLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPL 526
Query: 577 DLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQD 608
D+S EG+ NW FM+ H W E +G WTL +++
Sbjct: 527 DVSTEGYNNWVFMSTHFWDENPQGVWTLGLEN 558
>gi|20336242 proprotein convertase subtilisin/kexin type 1
preproprotein [Homo sapiens]
Length = 753
Score = 583 bits (1502), Expect = e-166
Identities = 296/570 (51%), Positives = 383/570 (67%), Gaps = 7/570 (1%)
Query: 51 WLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFY 110
++L A A SA R + N WA ++ GGP A +A GY LGQIG+LE++Y F
Sbjct: 13 FVLFCAWCALNSAKAKRQ-FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFK 71
Query: 111 HSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWY 170
H +RS S+ L D +V W +QQ K R KR D FNDP+W+ WY
Sbjct: 72 HKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWY 131
Query: 171 LHCGDKNSRC-RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNG 229
L + + +++V W++G TGK VV+T+LDDG+E NH D+ NYD ASYD N
Sbjct: 132 LQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFND 191
Query: 230 NDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEA 289
ND+DP PRYD +NENKHGTRCAGE+A ANN C VG+AYN+K+GGIRMLDG VTD +EA
Sbjct: 192 NDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEA 251
Query: 290 KSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGG 349
S+G P ++DIYSASWGP+DDGKTV+GPGRLA++AFEYG+K+GRQG GSIFVWASGNGG
Sbjct: 252 SSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGG 311
Query: 350 REGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLR 409
R+GD C CDGYT+SIYTIS+SSA++ G PWY E+C+STLAT+YSSG + +++I + DL
Sbjct: 312 RQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLH 371
Query: 410 QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVNGA 468
CT+ HTGTS SAP+ AGI ALALEAN LTWRD+QHL+V TS L + WK NGA
Sbjct: 372 NDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGA 431
Query: 469 GHKVSHFYGFGLVDAEALV--VEAKKWTAVPSQHMCVAA-SDKRPRSIPLVQVLRTTALT 525
G V+ +GFGL++A+ALV + + W +VP + CV +D PR++ + T
Sbjct: 432 GLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPT 491
Query: 526 SACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTN 585
AC E + + LEHV +I + RRGDL + L S +GT + LLA+R D S GF N
Sbjct: 492 RAC-EGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKN 550
Query: 586 WEFMTVHCWGEKAEGQWTLEIQDLPSQVRN 615
W+FM+VH WGE G WTL I D+ +++N
Sbjct: 551 WDFMSVHTWGENPIGTWTLRITDMSGRIQN 580
>gi|20336244 proprotein convertase subtilisin/kexin type 2 [Homo
sapiens]
Length = 638
Score = 484 bits (1245), Expect = e-136
Identities = 268/553 (48%), Positives = 346/553 (62%), Gaps = 12/553 (2%)
Query: 63 APPPRPVYTNHWAVQV-LGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLS 121
A RPV+TNH+ V++ GG +A +VAA HG+ + ++ E YHFYH+ K
Sbjct: 23 ASAERPVFTNHFLVELHKGGEDKARQVAAEHGF-GVRKLPFAEGLYHFYHNGLAKAKRRR 81
Query: 122 SRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQA-LYFNDPIWSNMWYL-HCGDKNSR 179
S L DP+VK QQE R KR R + + NDP+++ WYL + G +
Sbjct: 82 SLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGT 141
Query: 180 CRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYD 239
++NV AW+ GYTGK V + I+DDGI+ HPDLA NY++ ASYD + ND P PRY
Sbjct: 142 PGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYT 201
Query: 240 ASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGD-VTDVVEAKSLGIRPNY 298
N HGTRCAGEV+A+ANN+ C VG+AYN+K+ GIRMLD +TD++EA S+ P
Sbjct: 202 DDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQL 261
Query: 299 IDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCD 358
IDIYSASWGP D+GKTVDGP L QA G+ KGR G GSI+VWASG+GG D C+CD
Sbjct: 262 IDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDD-CNCD 320
Query: 359 GYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFY--ERKIVTTDLRQRCTDGH 416
GY +S++TIS++SA +G Y E C+STLA+T+S+G E + TTDL CT H
Sbjct: 321 GYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRH 380
Query: 417 TGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSR--PAHLKASDWKVNGAGHKVSH 474
+GTS +AP AG+ ALALEAN LTWRD+QHL V TS+ H + W+ NG G + +H
Sbjct: 381 SGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNH 440
Query: 475 FYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQ 534
+G+G++DA A+V AK W VP + CV S + P IP L T T AC E +
Sbjct: 441 LFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDAC-EGKEN 499
Query: 535 RVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLL-DLSNEGFTNWEFMTVHC 593
V YLEHV +++ RRGDL I + SP GTKS LL++R D S GF W FMT H
Sbjct: 500 FVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHT 559
Query: 594 WGEKAEGQWTLEI 606
WGE A G WTLE+
Sbjct: 560 WGEDARGTWTLEL 572
>gi|20336248 proprotein convertase subtilisin/kexin type 7
preproprotein [Homo sapiens]
Length = 785
Score = 446 bits (1148), Expect = e-125
Identities = 239/534 (44%), Positives = 317/534 (59%), Gaps = 19/534 (3%)
Query: 84 EADRVAAAHGYLNLGQIGNLEDYYHFY----HSKTFKRSTLSSRGPHTFLRMDPQVKWLQ 139
+AD +A A G +N G+IG L+ +Y F H + + + L V+W
Sbjct: 73 QADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQ-VEAVLAGHEAVRWHS 131
Query: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNV 199
+Q + RR KR V +FNDP + W+L+ R ++NV W+R TG+ V
Sbjct: 132 EQRLLRRAKRSV-------HFNDPKYPQQWHLNNRRSPGR---DINVTGVWERNVTGRGV 181
Query: 200 VVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASAN 259
V ++DDG+E D+APNY SYD+N ND DP P D N N HGTRCAGE+AA N
Sbjct: 182 TVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPN 241
Query: 260 NSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPG 319
NS+C VG+AY ++I GIR+LDG +TD +EA + DIYS SWGPDDDGKTVDGP
Sbjct: 242 NSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPH 301
Query: 320 RLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKP 379
+L K A ++G+ GRQG GSIFV ASGNGG+ D C+ DGY NSIYT+++ + E G P
Sbjct: 302 QLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMP 361
Query: 380 WYLEECASTLATTYSSGAFYERKIVTTDLRQR----CTDGHTGTSVSAPMVAGIIALALE 435
+Y EECAS LA T+S G R IVTTD + CT+GHTGTS +AP+ AG+IAL L+
Sbjct: 362 FYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQ 421
Query: 436 ANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTA 495
LTWRDVQH++V T+ + ++W N AG SH +GFGL++A LV AK WT+
Sbjct: 422 VRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTS 481
Query: 496 VPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGD 555
VP V+ K ++IP + + + LEHV V SI+HPRRG
Sbjct: 482 VPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGS 541
Query: 556 LQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDL 609
L++ L PSG S + A R +D GF +W F TV CWGE+A G + L I+D+
Sbjct: 542 LELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDV 595
>gi|171543895 ataxin 2 [Homo sapiens]
Length = 1313
Score = 48.5 bits (114), Expect = 2e-05
Identities = 33/73 (45%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 2 PPRAPPAPGPRPPPRAAAATDTAAGA-GGAGGAGGAGGPGFRPL-----APRPWRWLLL- 54
P APP PGP PPP ++ +A+ G G GGA PG R L PRP+ LLL
Sbjct: 51 PSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLP 110
Query: 55 LALPAACSAPPPR 67
LA P A A P R
Sbjct: 111 LASPGAPPAAPTR 123
>gi|28269693 xylosyltransferase I [Homo sapiens]
Length = 959
Score = 45.8 bits (107), Expect = 1e-04
Identities = 30/73 (41%), Positives = 33/73 (45%), Gaps = 7/73 (9%)
Query: 6 PPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFR-------PLAPRPWRWLLLLALP 58
PPAP PR R A AA GG GG GG GG G + P PR + ALP
Sbjct: 58 PPAPAPRRERRDLPAEPAAARGGGGGGGGGGGGRGPQARARGGGPGEPRGQQPASRGALP 117
Query: 59 AACSAPPPRPVYT 71
A P P P+ T
Sbjct: 118 ARALDPHPSPLIT 130
>gi|4758392 forkhead box D1 [Homo sapiens]
Length = 465
Score = 45.4 bits (106), Expect = 2e-04
Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 5/67 (7%)
Query: 5 APPAPG----PRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
APPA G P P P A A G GGAGG G AG PL P+ ++ L+ + A
Sbjct: 80 APPAGGSPAPPGPAPAAGAGAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITM-AI 138
Query: 61 CSAPPPR 67
+P R
Sbjct: 139 LQSPKKR 145
Score = 30.0 bits (66), Expect = 6.6
Identities = 20/43 (46%), Positives = 20/43 (46%), Gaps = 7/43 (16%)
Query: 11 PRPPPRAAAATDTAAGAGGAGGAGGAGGPG-----FRPLAPRP 48
P PP AAAA GAG AGGAG P F P P P
Sbjct: 225 PLLPPNAAAAESLL--LRGAGAAGGAGDPAAAAALFPPAPPPP 265
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 45.4 bits (106), Expect = 2e-04
Identities = 36/99 (36%), Positives = 43/99 (43%), Gaps = 15/99 (15%)
Query: 7 PAPGPRPPPRAAAATDTAAGAG--------GAGGAGGAGGPGFRPLAPRP----WRWLLL 54
P+PG P +A + TA +G G GGAGG GG G+RP+ P +
Sbjct: 339 PSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGG-GYRPIIQSPGYKTGKGGYG 397
Query: 55 LALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHG 93
A A PPPR T Q LGGPA A A G
Sbjct: 398 AAAGGATRPPPPRSTATP--KCQSLGGPAAAYATGKASG 434
Score = 33.1 bits (74), Expect = 0.78
Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 9/45 (20%)
Query: 12 RPPPRAAAATDTAAGAGG---------AGGAGGAGGPGFRPLAPR 47
RPPP + AT GG A GAGGAGG + P P+
Sbjct: 405 RPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQ 449
Score = 31.6 bits (70), Expect = 2.3
Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 2 PPRAPPAPGPRP--PPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPW 49
PPR+ P + P AA AT A+GAGGAGG + G L P+ +
Sbjct: 408 PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAY 457
Score = 31.2 bits (69), Expect = 3.0
Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 16/82 (19%)
Query: 2 PPRAPPAPGPRPPPR---------------AAAATDTAAGAGGAGGAGGAGGPGFRPLAP 46
PP P P P PPPR AAAA ++ GA P R L P
Sbjct: 225 PPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERAL-P 283
Query: 47 RPWRWLLLLALPAACSAPPPRP 68
R + PA+ PPP P
Sbjct: 284 RQDTVIKHYQRPASAQPPPPPP 305
Score = 31.2 bits (69), Expect = 3.0
Identities = 23/68 (33%), Positives = 26/68 (38%), Gaps = 10/68 (14%)
Query: 2 PPRAPPAPGPRP-PPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA 60
PP PPAP P+P PP A + A P PL P P P A
Sbjct: 1458 PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP---------PPA 1508
Query: 61 CSAPPPRP 68
+PPP P
Sbjct: 1509 MPSPPPPP 1516
Score = 30.8 bits (68), Expect = 3.9
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
Query: 11 PRPPPRAAA--------ATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACS 62
P PP + A A D + G GG+GGAGG G + P R+ L + + S
Sbjct: 650 PSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSAS 709
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 43.1 bits (100), Expect = 8e-04
Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 15/73 (20%)
Query: 2 PPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAAC 61
PPRAPP P P PPP + A G A G A P P +P P A P++C
Sbjct: 785 PPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAP--IPRSPLP-------AGPSSC 835
Query: 62 SAP------PPRP 68
++P PPRP
Sbjct: 836 TSPRSPLPAPPRP 848
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
sapiens]
Length = 1336
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/64 (42%), Positives = 30/64 (46%), Gaps = 13/64 (20%)
Query: 5 APPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAP 64
+PPAP P + GAGGAGG GGAGG P AP P R +AP
Sbjct: 1054 SPPAPARWPRSDPESQPLLGPGAGGAGGTGGAGGGA--PAAPPPCR-----------AAP 1100
Query: 65 PPRP 68
PP P
Sbjct: 1101 PPCP 1104
Score = 33.1 bits (74), Expect = 0.78
Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 10/68 (14%)
Query: 3 PRAPPAPGPRP-PPRAAAATDTAAGAGGAGGAGGAG-GPGFR----PLAPRPWRWLLLLA 56
P PAPGP P PR A+ D GAG GGAG GF P+ P+ L L
Sbjct: 921 PAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLADGFHRYYGPIEPQG----LGLG 976
Query: 57 LPAACSAP 64
L A +AP
Sbjct: 977 LGEARAAP 984
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 42.4 bits (98), Expect = 0.001
Identities = 22/39 (56%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 2 PPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAG-GAGGP 39
PP PP P P+PPP GAGGAGGAG GAG P
Sbjct: 14 PPPPPPQPQPQPPP-PPPGPGAGPGAGGAGGAGAGAGDP 51
Score = 40.4 bits (93), Expect = 0.005
Identities = 18/36 (50%), Positives = 20/36 (55%)
Query: 2 PPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAG 37
PP APP P P+P P+ GAGGAGGAG
Sbjct: 10 PPPAPPPPPPQPQPQPPPPPPGPGAGPGAGGAGGAG 45
>gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo
sapiens]
Length = 304
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 30/105 (28%)
Query: 6 PPAPGPRPP-------PRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALP 58
P P PRPP PR A + G GAGG GGA + + PRP R L+
Sbjct: 210 PTPPRPRPPGLRSGDVPRGGARVERPTGRRGAGGRGGA-----QRIPPRPLRRLV----- 259
Query: 59 AACSAPPPRPVYTNHWA--VQVLGGPAEA----DRVAAAHGYLNL 97
P + +HW+ ++L G A A +R+ AAH Y ++
Sbjct: 260 -------PIHPHPSHWSFCTRLLEGWAPAVTHSERLVAAHTYTHI 297
>gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo
sapiens]
Length = 304
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 30/105 (28%)
Query: 6 PPAPGPRPP-------PRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALP 58
P P PRPP PR A + G GAGG GGA + + PRP R L+
Sbjct: 210 PTPPRPRPPGLRSGDVPRGGARVERPTGRRGAGGRGGA-----QRIPPRPLRRLV----- 259
Query: 59 AACSAPPPRPVYTNHWA--VQVLGGPAEA----DRVAAAHGYLNL 97
P + +HW+ ++L G A A +R+ AAH Y ++
Sbjct: 260 -------PIHPHPSHWSFCTRLLEGWAPAVTHSERLVAAHTYTHI 297
>gi|32171221 GRP1 (general receptor for phosphoinositides
1)-associated scaffold protein [Homo sapiens]
Length = 395
Score = 41.2 bits (95), Expect = 0.003
Identities = 18/38 (47%), Positives = 20/38 (52%)
Query: 3 PRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPG 40
P PA GP P PRAA + + G GG GG G PG
Sbjct: 312 PAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPG 349
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 40.8 bits (94), Expect = 0.004
Identities = 22/43 (51%), Positives = 23/43 (53%), Gaps = 6/43 (13%)
Query: 3 PRAPPAPGPRPPPRA------AAATDTAAGAGGAGGAGGAGGP 39
P AP P PPP A AAA + GAG GGAGG GGP
Sbjct: 338 PAGGAAPPPPPPPGALGSFALAAAANGYLGAGAGGGAGGGGGP 380
Score = 30.4 bits (67), Expect = 5.1
Identities = 27/87 (31%), Positives = 31/87 (35%), Gaps = 32/87 (36%)
Query: 15 PRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAPPPRPVYTNHW 74
P AAAA + A G GAG AGG A PPP P +
Sbjct: 318 PAAAAAANLLASYAGEAGAGPAGG---------------------AAPPPPPPPGALGSF 356
Query: 75 AVQVLGGPAEADRVAAAHGYLNLGQIG 101
A+ AAA+GYL G G
Sbjct: 357 AL-----------AAAANGYLGAGAGG 372
>gi|5454106 TBP-related factor 10 [Homo sapiens]
Length = 218
Score = 40.0 bits (92), Expect = 0.006
Identities = 40/115 (34%), Positives = 47/115 (40%), Gaps = 12/115 (10%)
Query: 2 PPRAPPAPGPRPP-------PRAAAATDTAAGAGGAGGAG-GAGGPGFRPLAPRPWRWLL 53
P A APGP PP P + AA + A+ AG AGG G GA G PLA R
Sbjct: 14 PASAASAPGPAPPVSAPAALPSSTAAENKASPAGTAGGPGAGAAAGGTGPLAARAGEPAE 73
Query: 54 L--LALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDY 106
A +A A PP +N V VL A D + + LEDY
Sbjct: 74 RRGAAPVSAGGAAPPEGAISN--GVYVLPSAANGDVKPVVSSTPLVDFLMQLEDY 126
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/42 (52%), Positives = 23/42 (54%), Gaps = 5/42 (11%)
Query: 6 PPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPR 47
PPAP P PPP A GAG GGAG + GPG P PR
Sbjct: 2462 PPAPPPPPPP----ADGGPRGAGDPGGAGASSGPG-APAEPR 2498
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 39.3 bits (90), Expect = 0.011
Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 2 PPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAAC 61
PP A AP P PPP A+ A +G G A GPG AP P AL A
Sbjct: 75 PPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTP-------ALVAGS 127
Query: 62 SAPPPRP 68
SA P P
Sbjct: 128 SAAAPFP 134
Score = 34.7 bits (78), Expect = 0.27
Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 12/72 (16%)
Query: 2 PPRAPPAPG-----PRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLA 56
PP A AP P PP +A ++ + GGAGG G L P P
Sbjct: 22 PPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPP-------P 74
Query: 57 LPAACSAPPPRP 68
P A +APPP P
Sbjct: 75 PPPATAAPPPPP 86
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 39.3 bits (90), Expect = 0.011
Identities = 22/54 (40%), Positives = 23/54 (42%), Gaps = 8/54 (14%)
Query: 3 PRAPPAPGPRPPPRAAAATDTAAGA--------GGAGGAGGAGGPGFRPLAPRP 48
P PP P PP AAA +AGA GG G G GPG AP P
Sbjct: 287 PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340
Score = 32.7 bits (73), Expect = 1.0
Identities = 34/104 (32%), Positives = 37/104 (35%), Gaps = 16/104 (15%)
Query: 2 PPRAPPAPG--------PRPPPRAAAATDTAAGA--GGAGGAG-----GAGGPGFRPLAP 46
PP PPAP P PP AA A A A GG+ GA AGGP P
Sbjct: 270 PPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP 329
Query: 47 RPWRWLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAA 90
P A P + P R V A Q L A A+
Sbjct: 330 GPGAAAAAPA-PGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372
Score = 30.4 bits (67), Expect = 5.1
Identities = 17/42 (40%), Positives = 18/42 (42%)
Query: 5 APPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP 46
A P P P P + A AA AG G G GPG P P
Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP 189
Score = 29.6 bits (65), Expect = 8.7
Identities = 22/64 (34%), Positives = 24/64 (37%), Gaps = 1/64 (1%)
Query: 5 APPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAP 64
APPA RPPP +A + A A AG P P P L A P P
Sbjct: 120 APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA-GPAKPAGPAALAARAGPGPGPGP 178
Query: 65 PPRP 68
P P
Sbjct: 179 GPGP 182
>gi|82546824 forkhead box K1 [Homo sapiens]
Length = 733
Score = 39.3 bits (90), Expect = 0.011
Identities = 19/41 (46%), Positives = 21/41 (51%), Gaps = 4/41 (9%)
Query: 2 PPRAP----PAPGPRPPPRAAAATDTAAGAGGAGGAGGAGG 38
PP AP P PGP PPP AGAG +GG+ G G
Sbjct: 39 PPPAPAQPQPPPGPPPPPPPPLPPGAIAGAGSSGGSSGVSG 79
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,164,518
Number of Sequences: 37866
Number of extensions: 1491621
Number of successful extensions: 20968
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 248
Number of HSP's successfully gapped in prelim test: 283
Number of HSP's that attempted gapping in prelim test: 15500
Number of HSP's gapped (non-prelim): 4385
length of query: 623
length of database: 18,247,518
effective HSP length: 108
effective length of query: 515
effective length of database: 14,157,990
effective search space: 7291364850
effective search space used: 7291364850
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.