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Search of human proteins with 193083185
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
(1093 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 2180 0.0
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 2163 0.0
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 2162 0.0
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 349 9e-96
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 345 1e-94
gi|158303333 synaptopodin isoform B [Homo sapiens] 112 2e-24
gi|40353727 synaptopodin isoform A [Homo sapiens] 100 6e-21
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 74 1e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 71 5e-12
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 71 5e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni... 71 5e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 69 2e-11
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 69 2e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 66 2e-10
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 65 3e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 65 3e-10
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 65 5e-10
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 65 5e-10
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 65 5e-10
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 65 5e-10
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 64 1e-09
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 62 3e-09
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 62 3e-09
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 62 4e-09
gi|118600967 shroom family member 4 [Homo sapiens] 61 7e-09
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens] 60 9e-09
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 60 9e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 60 9e-09
gi|150418009 transforming, acidic coiled-coil containing protein... 60 1e-08
gi|45827755 transforming, acidic coiled-coil containing protein ... 60 1e-08
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 2180 bits (5650), Expect = 0.0
Identities = 1093/1093 (100%), Positives = 1093/1093 (100%)
Query: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP
Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
Query: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
Query: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE
Sbjct: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
Query: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH
Sbjct: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
Query: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR
Sbjct: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
Query: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR
Sbjct: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
Query: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE
Sbjct: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
Query: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK
Sbjct: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
Query: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE
Sbjct: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
Query: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA
Sbjct: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
Query: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF
Sbjct: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
Query: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK
Sbjct: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
Query: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW
Sbjct: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
Query: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY
Sbjct: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
Query: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA
Sbjct: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
Query: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN
Sbjct: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
Query: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ
Sbjct: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
Query: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG
Sbjct: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
Query: 1081 VTIQVWKPSVVEE 1093
VTIQVWKPSVVEE
Sbjct: 1081 VTIQVWKPSVVEE 1093
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 2163 bits (5605), Expect = 0.0
Identities = 1085/1085 (100%), Positives = 1085/1085 (100%)
Query: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP
Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
Query: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
Query: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE
Sbjct: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
Query: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH
Sbjct: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
Query: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR
Sbjct: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
Query: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR
Sbjct: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
Query: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE
Sbjct: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
Query: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK
Sbjct: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
Query: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE
Sbjct: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
Query: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA
Sbjct: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
Query: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF
Sbjct: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
Query: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK
Sbjct: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
Query: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW
Sbjct: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
Query: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY
Sbjct: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
Query: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA
Sbjct: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
Query: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN
Sbjct: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
Query: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ
Sbjct: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
Query: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG
Sbjct: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
Query: 1081 VTIQV 1085
VTIQV
Sbjct: 1081 VTIQV 1085
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 2162 bits (5601), Expect = 0.0
Identities = 1084/1084 (100%), Positives = 1084/1084 (100%)
Query: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP
Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
Query: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
Query: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE
Sbjct: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
Query: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH
Sbjct: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
Query: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR
Sbjct: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
Query: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR
Sbjct: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
Query: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE
Sbjct: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
Query: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK
Sbjct: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
Query: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE
Sbjct: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
Query: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA
Sbjct: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
Query: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF
Sbjct: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
Query: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK
Sbjct: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
Query: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW
Sbjct: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
Query: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY
Sbjct: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
Query: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA
Sbjct: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
Query: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN
Sbjct: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
Query: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ
Sbjct: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
Query: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG
Sbjct: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
Query: 1081 VTIQ 1084
VTIQ
Sbjct: 1081 VTIQ 1084
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 349 bits (895), Expect = 9e-96
Identities = 290/832 (34%), Positives = 389/832 (46%), Gaps = 189/832 (22%)
Query: 343 KDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRR 402
+D + + +A+ A+L+R+ESL EK +KEAK+KC++IA LLT APNP+SKGVLMFKKRR+
Sbjct: 244 EDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQ 303
Query: 403 RARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNF 462
RA+KYTLVS+G EEE+G SESE+DEE SD T
Sbjct: 304 RAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFSDARSLTN--QS 350
Query: 463 DWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMDQITAQKEEDKV 514
DWDS +D+E + + G + L + +G+G +F ++R+R D T +
Sbjct: 351 DWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL----- 405
Query: 515 GGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSG 572
+R + AA +GL++ Q E+ S + + P Q G
Sbjct: 406 ----ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-----PFQPGGGA 456
Query: 573 TSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPIADFPAPPPY-S 623
+ +I NR+A+PF PG Q T P +P R S PAPPP+ S
Sbjct: 457 PTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511
Query: 624 AVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ-----------PAPW 655
+ P P +F+ GV S P++G P P P PAP
Sbjct: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571
Query: 656 SQPAFYDSS------------------------ERIASRDERISVPAKRTGILQEAKRRS 691
S A ++ E ++R++RISVPA RTGILQEA+RR
Sbjct: 572 SAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRG 631
Query: 692 TTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSS 749
T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSLGAEACNFMQ
Sbjct: 632 TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSLGAEACNFMQPV 690
Query: 750 SAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800
A+ KTPPP+APK + P+TP +P P VAP
Sbjct: 691 GARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK------------- 728
Query: 801 TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVG 860
PP+R G G AS P+P
Sbjct: 729 -------------PPSR--------GLLDGLVNGAASSAGIPEP---------------- 751
Query: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSLPASWKYSSNVR 918
P + GRG +LFAKRQSR ++YVV+ R+ SPTPSLP SWKYS N+R
Sbjct: 752 -----PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIR 806
Query: 919 APPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFT 978
APPP+AYNP+ SP +P AA + +Q + K+G + ALD M+HQPYQL ++F
Sbjct: 807 APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRHQPYQLKTAMFC 863
Query: 979 FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFA 1038
F G S K +++ P P A P + + P
Sbjct: 864 FDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTE 923
Query: 1039 EASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGVTIQVWKP 1088
AS+PV P P P +P+ S SS F RP+FSA ++G+ VW+P
Sbjct: 924 LASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHVWRP 972
Score = 84.3 bits (207), Expect = 6e-16
Identities = 36/86 (41%), Positives = 63/86 (73%)
Query: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
MG + + ++++GGAPWGFRL GG EQ++PLQV+KIR +S+A +GL E D++++ING
Sbjct: 1 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVS 60
Query: 61 CADLTYPEVIKLMESITDSLQMLIKR 86
C +L++ + L+++ + L + ++R
Sbjct: 61 CTNLSHASAMSLIDASGNQLVLTVQR 86
Score = 44.7 bits (104), Expect = 5e-04
Identities = 80/352 (22%), Positives = 124/352 (35%), Gaps = 51/352 (14%)
Query: 758 PVAPKPAVKSSSSQPVTPVS-PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA 816
P P P + SQ + VS P W G A PPA P + P
Sbjct: 181 PAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLP---------------HGPL 225
Query: 817 RPASTL-NVAGPFKGPQAAVASQNYTPK-PTVSTPTVNAVQPGAVGPS-----------N 863
RP L + GP P A + YT K ++Q ++ +
Sbjct: 226 RPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLT 285
Query: 864 ELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQS----PTPSLPASWKYSSNVRA 919
P +G +F KR+ R +KY + S A + PT + S+ R+
Sbjct: 286 AAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARS 345
Query: 920 PPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNAS---L 976
+ LA S+ S Q S +G + + + + + Q + ++S L
Sbjct: 346 LTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL 405
Query: 977 FTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNA--ASPTNVQASSVYSVPAYTSPP 1034
+P +G +S + SA LPP P+ A ASP Q PA P
Sbjct: 406 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA----P 461
Query: 1035 SFFAEASSPVSAS-----PVPVGI---PTSPKQESAS-SSYFVAPRPKFSAK 1077
S F ++ P + P + P +PK+ + S AP P S++
Sbjct: 462 SIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQ 513
>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
Length = 753
Score = 345 bits (886), Expect = 1e-94
Identities = 291/843 (34%), Positives = 391/843 (46%), Gaps = 194/843 (23%)
Query: 337 EDPRSEKDHSR-----PHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNS 391
++P S+ + + P + +A L+R+ESL EK +KEAK+KC++IA LLT APNP+S
Sbjct: 9 QEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHS 68
Query: 392 KGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLS 451
KGVLMFKKRR+RA+KYTLVS+G EEE+G SESE+DEE S
Sbjct: 69 KGVLMFKKRRQRAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFS 117
Query: 452 DVDDNTQVVNFDWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMD 503
D T DWDS +D+E + + G + L + +G+G +F ++R+R D
Sbjct: 118 DARSLTN--QSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRAD 175
Query: 504 QITAQKEEDKVGGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGL 561
T + +R + AA +GL++ Q E+ S + +
Sbjct: 176 SSTQEL---------ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-- 224
Query: 562 GHVPQQNGFSGTSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPI 613
P Q G + +I NR+A+PF PG Q T P +P R S
Sbjct: 225 ---PFQPGGGAPTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG 276
Query: 614 ADFPAPPPY-SAVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ---- 651
PAPPP+ S+ P P +F+ GV S P++G P P P
Sbjct: 277 GLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVT 336
Query: 652 -------PAPWSQPAFYDSS------------------------ERIASRDERISVPAKR 680
PAP S A ++ E ++R++RISVPA R
Sbjct: 337 PGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 396
Query: 681 TGILQEAKRRSTTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSL 738
TGILQEA+RR T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSL
Sbjct: 397 TGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSL 455
Query: 739 GAEACNFMQSSSAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789
GAEACNFMQ A+ KTPPP+APK + P+TP +P P VAP
Sbjct: 456 GAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK-- 504
Query: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
PP+R G G AS P+P
Sbjct: 505 ------------------------PPSR--------GLLDGLVNGAASSAGIPEP----- 527
Query: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSL 907
P + GRG +LFAKRQSR ++YVV+ R+ SPTPSL
Sbjct: 528 ----------------PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSL 571
Query: 908 PASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKH 967
P SWKYS N+RAPPP+AYNP+ SP +P AA + +Q + K+G + ALD M+H
Sbjct: 572 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRH 628
Query: 968 QPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSV 1027
QPYQL ++F F G S K +++ P P A P + +
Sbjct: 629 QPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA 688
Query: 1028 PAYTSPPSFFAEASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGVTIQV 1085
P AS+PV P P P +P+ S SS F RP+FSA ++G+ V
Sbjct: 689 TTLDEPIWRTELASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHV 745
Query: 1086 WKP 1088
W+P
Sbjct: 746 WRP 748
>gi|158303333 synaptopodin isoform B [Homo sapiens]
Length = 685
Score = 112 bits (280), Expect = 2e-24
Identities = 134/493 (27%), Positives = 201/493 (40%), Gaps = 137/493 (27%)
Query: 612 PIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRD 671
P+ +F APP Y+ ++P+A + PP S Y SS+ +S
Sbjct: 311 PLGNFTAPPTYTETLS---------TAPLASWVRSPP-------SYSVLYPSSDPKSSHL 354
Query: 672 ERISVPAKRTGILQEAK-RRSTTKPMFTFKE-PKVSPNPELLSLLQNSEGKRGTGAGGDS 729
+ +VPA +TGIL+E+ RR + K MFTF E PKV+PNP+LL L+Q ++ KR G+
Sbjct: 355 KGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEV 414
Query: 730 GPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789
G EE+ +LGAEA NF Q + + + P A + V P W+ + +
Sbjct: 415 GVEEEPFALGAEASNFQQEPAPRDRASPAAAEE-------------VVPEWASCLKSPRI 461
Query: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPK------ 843
A P P++ +S K A+ AR S + + + S ++TP+
Sbjct: 462 QAKPKPKPNQNLSEASGKGAELY---ARRQSRME--------KYVIESSSHTPELARCPS 510
Query: 844 PTVSTPT-----VNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAA 898
PT+S P+ NA PGA ++ P + S Y+ ++ ++
Sbjct: 511 PTMSLPSSWKYPTNA--PGAFRVASRSPART--------PPASLYHGYLPENGVLR---- 556
Query: 899 RAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKP 958
PT P + P +PI P+ K P AA P+K
Sbjct: 557 --PEPTKQPPYQLR-------PSLFVLSPIKEPA------KVSPRAASPAKP-------- 593
Query: 959 LNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTN 1018
++LD++ + P K ALPP P
Sbjct: 594 -SSLDLVPNLP---------------------------------KGALPPSPA------- 612
Query: 1019 VQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV--APRPKFSA 1076
+ S S YTSP ++ P + SP P G SP S + S APRP FS
Sbjct: 613 LPRPSRSSPGLYTSPGQ---DSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQAPRPSFST 668
Query: 1077 KKSGVTIQVWKPS 1089
+ +G+ QVWKPS
Sbjct: 669 RNAGIEAQVWKPS 681
Score = 36.6 bits (83), Expect = 0.13
Identities = 41/194 (21%), Positives = 71/194 (36%), Gaps = 26/194 (13%)
Query: 484 LPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEES 543
L + +GKGA ++A+R+ RM++ + TP + + T L ++ Y +
Sbjct: 473 LSEASGKGAELYARRQSRMEKYVIESSSH----TPELARCPSPTMSLPSSWKYPTNAPGA 528
Query: 544 VRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPF 603
R S P + + G +P N +P P QP
Sbjct: 529 FRV----------ASRSPARTPPASLYHG---------YLPENGVLRPEP--TKQPPYQL 567
Query: 604 SPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS 663
P+ + SPI + P +A P + + P P P+P+ S P Y S
Sbjct: 568 RPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSR-SSPGLYTS 626
Query: 664 SERIASRDERISVP 677
+ + + +S P
Sbjct: 627 PGQDSLQPTAVSPP 640
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 100 bits (250), Expect = 6e-21
Identities = 141/577 (24%), Positives = 214/577 (37%), Gaps = 151/577 (26%)
Query: 612 PIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRD 671
P+ +F APP Y+ ++P+A + PP S Y SS+ +S
Sbjct: 311 PLGNFTAPPTYTETLS---------TAPLASWVRSPP-------SYSVLYPSSDPKSSHL 354
Query: 672 ERISVPAKRTGILQEAK-RRSTTKPMFTFKE-PKVSPNPELLSLLQNSEGKRGTGAGGDS 729
+ +VPA +TGIL+E+ RR + K MFTF E PKV+PNP+LL L+Q ++ KR G+
Sbjct: 355 KGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEV 414
Query: 730 GPEEDYLSLGAEACNFMQSSSAKQKTPPPVA-------------------PKP------- 763
G EE+ +LGAEA NF Q + + + P A PKP
Sbjct: 415 GVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLS 474
Query: 764 --------------------AVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVV 803
++SSS P P SP ++ +PT+ P V
Sbjct: 475 EASGKGAELYARRQSRMEKYVIESSSHTPELARCP--SPTMSLPSSWKYPTNAPGAFRVA 532
Query: 804 SSIKIAQP--------------------SYPPARPASTLNVAGPFKG------------- 830
S P PP + +L V P K
Sbjct: 533 SRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAK 592
Query: 831 ----------PQAAVASQNYTPKPTVSTPTV------NAVQPGAVGP--SNELPGMSGRG 872
P+ A+ P+P+ S+P + +++QP AV P ++ +S
Sbjct: 593 PSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSR 652
Query: 873 AQLFAKRQSRMEKYVVDSDTVQAHAARAQSPT-----------PS------LPASWK--Y 913
A +Q+ + + ++A R PT PS P W+
Sbjct: 653 AWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGR 712
Query: 914 SSNVRAPPPVAYNPIHSPSY---PLAALKSQPSAAQPSK-MGKKKGKKPLNALDVMKHQP 969
S++ +PPP+ P SPS+ ++ L+ + A PS+ + + +NA P
Sbjct: 713 GSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASP 772
Query: 970 YQLNA-SLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVP 1028
A + F PP A P M+ P RP +AA P ++ +P
Sbjct: 773 RSAGAENPRPFSPPRAPPPPPPPPPPPPR----MRSPQPARPGSAAVP----GAAFAPIP 824
Query: 1029 AYTSP--PSFFAEASSPVSASPVPVGIPTSPKQESAS 1063
P PS SP+ A P P SP S
Sbjct: 825 RSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVS 861
Score = 94.7 bits (234), Expect = 4e-19
Identities = 80/235 (34%), Positives = 109/235 (46%), Gaps = 38/235 (16%)
Query: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAP 920
P+ L SG+GA+L+A+RQSRMEKYV++S + AR SPT SLP+SWKY +N
Sbjct: 469 PNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNA--- 525
Query: 921 PPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNAL---DVMKHQPYQLNASLF 977
P A+ P+ P+ + G P N + + K PYQL SLF
Sbjct: 526 -PGAFR----------VASRSPARTPPASL--YHGYLPENGVLRPEPTKQPPYQLRPSLF 572
Query: 978 TFQP-PDAKDGLPQKSSVKVNSALAM-----KQALPPRPVNAASPTNVQASSVYSVPAYT 1031
P + P+ +S S+L + K ALPP P + S S YT
Sbjct: 573 VLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPA-------LPRPSRSSPGLYT 625
Query: 1032 SPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV--APRPKFSAKKSGVTIQ 1084
SP ++ P + SP P G SP S + S APRP FS + +G+ Q
Sbjct: 626 SPGQ---DSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQ 676
Score = 49.3 bits (116), Expect = 2e-05
Identities = 98/473 (20%), Positives = 162/473 (34%), Gaps = 85/473 (17%)
Query: 484 LPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEES 543
L + +GKGA ++A+R+ RM++ + TP + + T L ++ Y +
Sbjct: 473 LSEASGKGAELYARRQSRMEKYVIESSSH----TPELARCPSPTMSLPSSWKYPTNAPGA 528
Query: 544 VRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPF 603
R S P + + G +P N +P P QP
Sbjct: 529 FRV----------ASRSPARTPPASLYHG---------YLPENGVLRPEP--TKQPPYQL 567
Query: 604 SPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS 663
P+ + SPI + P +A P + + P P P+P+ S P Y S
Sbjct: 568 RPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSR-SSPGLYTS 626
Query: 664 SERIASRDERISVP------AKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNS 717
+ + + +S P + + +P F+ + + SL +
Sbjct: 627 PGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP 686
Query: 718 EGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVS 777
GA + ++S G + + +PPP+ P P P+S
Sbjct: 687 PWT--PGASRPPSSLDGWVSPGP----WEPGRGSSMSSPPPLPPPP-----------PMS 729
Query: 778 PVWSP-GVAPTQPP--AFPTSNPSKGTVVSSI-KIAQPSYPPARPASTLNVAGPFKGPQA 833
P WS V+P +P A P S + + +I A+ R A N PF P+A
Sbjct: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPR-PFSPPRA 788
Query: 834 AVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTV 893
P P P + + QP G S +PG
Sbjct: 789 PPPP----PPPPPPPPRMRSPQPARPG-SAAVPGA------------------------- 818
Query: 894 QAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQ 946
A A +SP P+ P+S + PP + SP+ +L S+ S A+
Sbjct: 819 -AFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK 870
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 73.6 bits (179), Expect = 1e-12
Identities = 111/473 (23%), Positives = 170/473 (35%), Gaps = 45/473 (9%)
Query: 615 DFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQ---PAFYDSSERIASRD 671
+ P P P F SP+ G + P PW+Q PA+ S + S
Sbjct: 1485 EIPTNIPGLGAAGPTGMFFGSAPSPMGGIS-----PAMTPWNQGATPAYGAWSPSVGSG- 1538
Query: 672 ERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGP 731
P A S P ++ P SP P G+ G GP
Sbjct: 1539 ---MTPGAAGFSPSAASDASGFSPGYS---PAWSPTP---------------GSPGSPGP 1577
Query: 732 EEDYLSL--GAEACNFMQSSSAKQKTPP----PVAPKPAVKSSSSQPVTPVSPVWSPGVA 785
Y+ GA + ++ +S A + P P +P + S S P +P SP +
Sbjct: 1578 SSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYS 1637
Query: 786 PTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPA-STLNVAGPFKGPQAAVASQNYTPKP 844
PT P PTS PS S PSY P P+ S + + P + S +Y+P
Sbjct: 1638 PTSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1696
Query: 845 TVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPT 904
+PT + P + S P S S S T ++ + + T
Sbjct: 1697 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYT 1756
Query: 905 PSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDV 964
P+ P S+ +S +P Y P SP+Y + P++ PS P +
Sbjct: 1757 PTSP-SYSPTSPSYSPTSPNYTPT-SPNYSPTSPSYSPTS--PSYSPTSPSYSPSSPRYT 1812
Query: 965 MKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRP-VNAASPTNVQASS 1023
+ Y ++ ++ P P+ + + + + + P P + SP S
Sbjct: 1813 PQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSP 1872
Query: 1024 VYSVPAYT-SPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFS 1075
YS + T SP + +SP + PV PTSPK S +Y PK+S
Sbjct: 1873 KYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTY-SPTSPKYS 1924
Score = 67.4 bits (163), Expect = 7e-11
Identities = 114/489 (23%), Positives = 170/489 (34%), Gaps = 66/489 (13%)
Query: 592 FPGSVNQPATPFSPTRNM----TSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAG--PAQ 645
F GS P SP +P +P S +TP FS +S +G P
Sbjct: 1502 FFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGY 1561
Query: 646 PPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVS 705
P W P P S + SS I S +S T E + P + P S
Sbjct: 1562 SPAW-SPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTP----QSPSYS 1616
Query: 706 PNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAV 765
P S + P S + N+ +S + T P +P
Sbjct: 1617 PTSPSYS---------------PTSP-----SYSPTSPNYSPTSPSYSPTSPSYSPTSPS 1656
Query: 766 KSSSSQPVTPVSPVW---SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTL 822
S +S +P SP + SP +PT P PTS PS S PSY P P+ +
Sbjct: 1657 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSP 1715
Query: 823 NVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSR 882
P + S +Y+P +PT + P + S P +
Sbjct: 1716 T------SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSY------- 1762
Query: 883 MEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQP 942
S T +++ + + TP+ P ++ +S +P +Y+P SPSY ++ + P
Sbjct: 1763 -------SPTSPSYSPTSPNYTPTSP-NYSPTSPSYSPTSPSYSPT-SPSYSPSSPRYTP 1813
Query: 943 SA-----AQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVN 997
+ + PS P + Y ++ +T P P+ S
Sbjct: 1814 QSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPK 1873
Query: 998 SALAMKQALPPRP-VNAASPTNVQASSVY--SVPAYTSPPSFFAEASSPVSASPVPVGIP 1054
+ P P + SPT S VY + P Y SP S +SP + P P
Sbjct: 1874 YSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKY-SPTSPTYSPTSPKYSPTSPTYSP 1932
Query: 1055 TSPKQESAS 1063
TSPK + S
Sbjct: 1933 TSPKGSTYS 1941
Score = 50.4 bits (119), Expect = 9e-06
Identities = 76/321 (23%), Positives = 115/321 (35%), Gaps = 48/321 (14%)
Query: 548 SSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTR 607
S S SY S + P +S TS + + P + + P S + + +SPT
Sbjct: 1679 SPTSPSYSPTSPS--YSPTSPSYSPTSPSYS-----PTSPSYSPTSPSYSPTSPSYSPTS 1731
Query: 608 NMTSPIADF--PAPPPYSAVTP--PPDAFSRGVSSPIAGPAQP---PPWPQPAPWSQPAF 660
SP + P P YS +P P + S +SP P P P P +P S P++
Sbjct: 1732 PSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTS-PSY 1790
Query: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
+S + S + R ++ + + P ++ P SP + S
Sbjct: 1791 SPTSPSYSPTSPSYSPSSPR--YTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSP 1848
Query: 721 RGTGAGGDSGPEEDYLS--LGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSP 778
S PE S + + +S T P +P S +S +P SP
Sbjct: 1849 --------SSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSP 1900
Query: 779 VW---SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAV 835
V+ SP +PT P PTS T P+Y P P KG +
Sbjct: 1901 VYTPTSPKYSPTSPTYSPTSPKYSPT--------SPTYSPTSP----------KGSTYSP 1942
Query: 836 ASQNYTPKPTVSTPTVNAVQP 856
S Y+P + T A+ P
Sbjct: 1943 TSPGYSPTSPTYSLTSPAISP 1963
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 71.2 bits (173), Expect = 5e-12
Identities = 120/517 (23%), Positives = 184/517 (35%), Gaps = 70/517 (13%)
Query: 584 PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFP--APPPYSAVTPPPDA--FSRGVSSP 639
P ++ P PA+P +++ P+ + P PP S ++PPP++ FS SP
Sbjct: 460 PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP 519
Query: 640 IAGPAQPPPWP------QPAPWSQPAF--YDSSERIASRDERISVPAKRTGILQEAKRRS 691
++ P + PP P P P + P ++ S +E + P L S
Sbjct: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
Query: 692 TTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSA 751
P +E +SP PE L E + PEE LS EA
Sbjct: 580 PMSP--PPEESPMSPPPEASRLFPPFE-----ESPLSPPPEESPLSPPPEASRLSPPPED 632
Query: 752 KQKTPP----PVAPKPAVKSSSSQP-VTPVSPVWSPGVAPTQPP--AFPTSNPSKGTVVS 804
+PP P++P P V S P V+ +SP P +P PP PTS P + + +S
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP--PPEESPLSPPPEESPTSPPPEASRLS 690
Query: 805 SIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNE 864
P+ PP P P + + P +P + + + P +E
Sbjct: 691 PPPEDSPTSPP-----------PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE 739
Query: 865 LPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVA 924
P +S R + R E+ + + H SP P P V
Sbjct: 740 GPHLSPRPEE--PHLSPRPEEPHLSPQAEEPHL----SPQPEEPCLC----------AVP 783
Query: 925 YNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDA 984
P SP L QP S ++ P+ + QP + + S + +P
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP--C 841
Query: 985 KDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSP--PSFFAEASS 1042
P++S + S K L PRP Q + +P + P PS
Sbjct: 842 LSPRPEESHL---SPELEKPPLSPRPEKPPEEPG-QCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 1043 PVSA-------SPVPVGIPTSPKQESASSSYFVAPRP 1072
P + SP+P +P SP E + S + P P
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934
Score = 57.8 bits (138), Expect = 6e-08
Identities = 91/402 (22%), Positives = 135/402 (33%), Gaps = 67/402 (16%)
Query: 601 TPFSPTRNMTSPIADFP-APPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPA 659
+P ++ P + P +PPP + T PP SR P P PPP PA S P
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA--SPP- 710
Query: 660 FYDSSERIASRDERISVPAKRTGIL------QEAKRRSTTKPMFTFKEPKVSPNPELLSL 713
D +S+P + + +L Q R +EP +SP PE L
Sbjct: 711 ---------PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL 761
Query: 714 LQNSEGKRGTGAGGD----SGPEEDYLSLGAEACNFMQSSSAKQKTP----PPVAPKPAV 765
+E + + + PEE +LS AE + +P P ++P P
Sbjct: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
Query: 766 KSSSSQP---------------------------------VTPVSPVWSPG--VAPTQPP 790
S QP P P PG AP + P
Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881
Query: 791 AF-PTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
F P PS ++ +++P PP P P P + P P +P
Sbjct: 882 LFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP 941
Query: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPA 909
+ A P A+ P EL GA+ + +S + ++++ A P P P
Sbjct: 942 IITAAAPPALSPLGELE--YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM 999
Query: 910 SWKYS--SNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSK 949
S S V P+ P+ PL P + PS+
Sbjct: 1000 ILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQ 1041
Score = 55.5 bits (132), Expect = 3e-07
Identities = 121/503 (24%), Positives = 178/503 (35%), Gaps = 93/503 (18%)
Query: 601 TPFSPTRN---MTSPIADFP-APPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWS 656
TP SP ++ P + P +PPP T PP SR P P PP P+ +P S
Sbjct: 534 TPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP--PEESPMS 591
Query: 657 QPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQN 716
P EA R F+E +SP PE L
Sbjct: 592 PP--------------------------PEASRLFP-----PFEESPLSPPPEESPLSPP 620
Query: 717 SEGKRGTGAGGDS----GPEEDYLSLGAEACNFMQSSSAKQKTPP----PVAPKPAVKSS 768
E R + DS PEE +S E + +PP P++P P +
Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 769 SSQP-VTPVSPVWSPGVAPTQPPA--FPTSNPSKGTVVSSIKIAQPSYP-PARPASTLNV 824
S P + +SP P +PT PP P S P + +++S P P P P
Sbjct: 681 SPPPEASRLSP--PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
Query: 825 AGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQS--- 881
GP P+ + +P+P + A +P + P E P + + Q+
Sbjct: 739 EGPHLSPRP--EEPHLSPRPEEPHLSPQAEEP-HLSPQPEEPCLCAVPEEPHLSPQAEGP 795
Query: 882 ----RMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSP----SY 933
+ E+ + T + H SP P P P + P SP S+
Sbjct: 796 HLSPQPEELHLSPQTEEPHL----SPVPEEPCLSPQPEESHLSPQ-SEEPCLSPRPEESH 850
Query: 934 PLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSS 993
L+ P + +P K ++ G+ P P +L F PP G P S
Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCP---------APEELP----LFPPP----GEPSLSP 893
Query: 994 VKVNSALAMKQALPPRPVN---AASPTNVQASSVYSVPAYTSPP--SFFAEASSPVSASP 1048
+ AL+ P P+ SP+ + S +P PP S A++P + SP
Sbjct: 894 LLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSP 953
Query: 1049 V-PVGIPTSPKQESASSSYFVAP 1070
+ + P K +S S AP
Sbjct: 954 LGELEYPFGAKGDSDPESPLAAP 976
Score = 44.7 bits (104), Expect = 5e-04
Identities = 114/492 (23%), Positives = 171/492 (34%), Gaps = 100/492 (20%)
Query: 511 EDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSK----SYIEVSHGL-GHVP 565
E K+ GTPS ++DAA L T +R ++ S R SS K + S L +
Sbjct: 4499 EQKLQGTPSNKEDAAARKPL--TPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLK 4556
Query: 566 QQNGFSGTSE---TANIQRMVPMNRTA-----KPFPGSVNQPATPFSPT--------RNM 609
Q+ +E TAN P G+ A P P N+
Sbjct: 4557 QELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNL 4616
Query: 610 TSPIADFPAPPPYSAVTPPPDAFSRGVS--SPIAGPAQPPPWPQPAPWSQPAFYDSSERI 667
++P P PP TPPP + V+ +P + P A S+ A D+SE +
Sbjct: 4617 SNP----PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSE-V 4671
Query: 668 ASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGG 727
S D ++P ++ + S E SP+ + +
Sbjct: 4672 KSLDLLAALPTPPHNQTEDVRMESD--------EDSDSPDSIVPA--------------- 4708
Query: 728 DSGPEEDYLSLGAEACNFMQSSSAK-QKTPPPVAPKPAVKSSSSQPVTP-VSPVWSPGVA 785
S PE LG EA F S + ++ ++P + +S PV P P + G+
Sbjct: 4709 -SSPES---ILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLE 4764
Query: 786 PTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPT 845
T KG+ VS + A A LN G AVA P
Sbjct: 4765 VPGKLPVTTWEKGKGSEVSVMLTVS-----AAAAKNLN------GVMVAVAELLSMKIPN 4813
Query: 846 V------STPTVNAVQPG---AVGPSNELPGMSGR----GAQLFAKRQSRMEKYVVDSDT 892
+P +P A GP + G+ G+ G + + + Y + S
Sbjct: 4814 SYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQL 4873
Query: 893 VQAHAARAQSPTPSLPASWKYSSNVR--------APPP---------VAYNPIHSPSYPL 935
+ +SP P P Y+ NV APPP +A +P P+ PL
Sbjct: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPL 4933
Query: 936 AALKSQPSAAQP 947
L ++P A P
Sbjct: 4934 VELPTEPLAEPP 4945
Score = 43.5 bits (101), Expect = 0.001
Identities = 105/505 (20%), Positives = 165/505 (32%), Gaps = 73/505 (14%)
Query: 573 TSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFP--APPPYSAVTPPPD 630
TS R+ P + P P +P + P + P PP S ++PPP+
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 631 AFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRR 690
A SR P P PP P+ +P S P + R+S P + + + +
Sbjct: 623 A-SRLSPPPEDSPMSPP--PEESPMSPPPEVSRLSPLPV-VSRLSPPPEESPLSPPPEES 678
Query: 691 STTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSS 750
T+ P + ++SP PE + + PE+ +SL E +
Sbjct: 679 PTSPPP---EASRLSPPPE-----DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 751 AKQKTP----PPVAPKPAVKSSSSQPVTP-VSP-VWSPGVAPTQPPAFPTSNPSKGTVVS 804
Q P P ++P+P S +P P +SP P ++P
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP------------------ 772
Query: 805 SIKIAQPSYP-----PARPASTLNVAGPFKGPQAA---VASQNYTP--KPTVSTPTVN-A 853
QP P P P + GP PQ ++ Q P P P ++
Sbjct: 773 -----QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQ 827
Query: 854 VQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPS----LPA 909
+ + P +E P +S R + + +EK + + Q P P P
Sbjct: 828 PEESHLSPQSEEPCLSPRPEE--SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885
Query: 910 SWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQP 969
+ S + P P P PL + +PS + PL P
Sbjct: 886 PGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL---------P 936
Query: 970 YQLNASLFTFQPP--DAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSV 1027
L+ + PP L K +S A P + P + V
Sbjct: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
Query: 1028 PAYTSPPSFFAEA--SSPVSASPVP 1050
P PPS + +SP+ P+P
Sbjct: 997 PPMILPPSPGSPVGPASPILMEPLP 1021
Score = 42.7 bits (99), Expect = 0.002
Identities = 97/432 (22%), Positives = 149/432 (34%), Gaps = 91/432 (21%)
Query: 587 RTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPP---------------DA 631
R +P P P+ P P D A PP + PP D
Sbjct: 2348 RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP 2407
Query: 632 FSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS--SERIASRDERISVPAKRTGILQEAKR 689
FSR +SP + + P P P S AF S + R S D P++ +
Sbjct: 2408 FSRVPASPQSQSSSQSPL-TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR-------PQS 2459
Query: 690 RSTTKPMFTFKEPKVSPNPELL----SLLQNSEGKRGTGAGGDSGPEEDYLSL--GAEAC 743
R P+ K P+ P PE+ SL S G G A +GP + + +
Sbjct: 2460 RDPFAPL--HKPPRPQP-PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPP 2516
Query: 744 NFMQS---------SSAKQKTPPPVAPKPAVKSSSSQPVTP----VSPVWSPGVAPTQP- 789
NF++S S + T P +P++K QP P ++ + PG +P
Sbjct: 2517 NFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQ 2576
Query: 790 ------------PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVAS 837
P+ PS G+ S ++ P RP S L P S
Sbjct: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLS-----PLRPPSVLPPPAP--DGSLPYLS 2629
Query: 838 QNYTPKPTVSTPTVNAVQPG---------AVGPSNELPGMSGRG-AQLFAKRQSRMEKYV 887
+ + +++P PG A P + PGMSG +L +RQ + + +
Sbjct: 2630 HGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLREL 2689
Query: 888 VDSDTVQAHAARAQSPTPSL-------PASWKYSSNVRAPPPVAYNPIHSPSYPLAALKS 940
+ +Q + R + T + P SW P A+ + P A +
Sbjct: 2690 LIRQQIQRNTLRQEKETAAAAAGAVGPPGSWG-----AEPSSPAFEQLSRGQTPFAGTQD 2744
Query: 941 QPS--AAQPSKM 950
+ S PSK+
Sbjct: 2745 KSSLVGLPPSKL 2756
Score = 36.2 bits (82), Expect = 0.17
Identities = 95/457 (20%), Positives = 148/457 (32%), Gaps = 118/457 (25%)
Query: 617 PAPPPYSAVTPPPD-AFSRGVSSP-IAGPAQPP--PWPQPAPWSQPAFYDSSERIASRDE 672
PAP PP + + S + P ++ P +PP P P+ P S S ++ D
Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934
Query: 673 RISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPE 732
+P + I+ A P +SP EL + GA GDS PE
Sbjct: 935 ---LPPPLSPIITAAA------------PPALSPLGEL---------EYPFGAKGDSDPE 970
Query: 733 EDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAF 792
S A P++P P + +PV P+ SPG +P P
Sbjct: 971 ---------------SPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG-SPVGP--- 1011
Query: 793 PTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVN 852
+S + +P P P Q ++ QN +P S P +
Sbjct: 1012 -----------ASPILMEPLPPQCSPLL-----------QHSLVPQN-SPPSQCSPPALP 1048
Query: 853 AVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPT-PSLPASW 911
P + P ++ G+S D + H + + P PA
Sbjct: 1049 LSVPSPLSPIGKVVGVS---------------------DEAELHEMETEKVSEPECPAL- 1086
Query: 912 KYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQP-- 969
P A +P+ SP L+ P+ A G + PL+ +D QP
Sbjct: 1087 ---------EPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP 1137
Query: 970 --------YQLNASLFTFQPPD-----AKDGLPQKSSVKVNSALAMKQALPPRPVNAASP 1016
+L S P + + P+ + +Q P PV P
Sbjct: 1138 GQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPP 1197
Query: 1017 TNVQASSVYSVPAYT-SPPSFFAEASSPVSASPVPVG 1052
T +++ V + + S S P+ SP P G
Sbjct: 1198 TLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEG 1234
Score = 35.0 bits (79), Expect = 0.39
Identities = 113/550 (20%), Positives = 168/550 (30%), Gaps = 118/550 (21%)
Query: 591 PFPGSVNQPATPFSPTRNMTSPIA----------------------DFPA------PPPY 622
P PG++ P +PT + SP D P PP
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
Query: 623 SAVTPPPDAFSRGVSSPI-----AGPAQPPPWPQP--APWSQPAFYDSSERIASRDERIS 675
A P D F + P+ P PP+P P AP P SS A +
Sbjct: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFH 2227
Query: 676 VPAKRTGILQEAKRRSTTKPMF-----------------TFKEPKVSPNP--ELLSLLQN 716
T Q + KP EP +SP P E L+
Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEV 2287
Query: 717 SEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPV 776
+ + G + P ++ + + + KTP ++S +P +P
Sbjct: 2288 KKEELGASSPSYGPPNLGFVDSPSSGTHL---GGLELKTPDVFKAPLTPRASQVEPQSP- 2343
Query: 777 SPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA-RPASTLNVAGPFKGPQAAV 835
G+ P +PP PS PS+P RP S P+ P
Sbjct: 2344 ----GLGLRPQEPPPAQALAPS-----------PPSHPDIFRPGS---YTDPYAQPP--- 2382
Query: 836 ASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQA 895
TP+P P P PS+ + Q + QS + T +
Sbjct: 2383 ----LTPRPQPPPPESCCALPPRSLPSDPFSRVPA-SPQSQSSSQSPL--------TPRP 2429
Query: 896 HAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKG 955
+A A P+P P ++P P + P S A +P QP ++ K G
Sbjct: 2430 LSAEAFCPSPVTP-------RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAG 2482
Query: 956 KKPLNALD-------VMKHQPYQLNASLFTFQPPD--------AKDGLPQKSSVKVNSAL 1000
+L + +L+A + + QPP+ A G P A+
Sbjct: 2483 SLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAV 2542
Query: 1001 AMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE 1060
PP P P + S P P S + + + P G P P
Sbjct: 2543 GEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQS---TNYTVATGNFHPSGSPLGPSSG 2599
Query: 1061 SASSSYFVAP 1070
S SY ++P
Sbjct: 2600 STGESYGLSP 2609
Score = 32.0 bits (71), Expect = 3.3
Identities = 36/139 (25%), Positives = 48/139 (34%), Gaps = 21/139 (15%)
Query: 521 EQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQ 580
++ Q+ +R T YQ ++ Q LG PQ GF G +T +Q
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGL-----------LGCQPQLGGFPGP-QTGPLQ 4275
Query: 581 RMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIAD--FPAPPPYSAVTPPPDAFSRGVSS 638
+ R P P P P T P+ P PPP S P + SS
Sbjct: 4276 ELGAGPRPQGP-------PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 639 PIAGPAQPPPWPQPAPWSQ 657
+ AQ PP P Q
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQ 4347
Score = 30.8 bits (68), Expect = 7.3
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 12/64 (18%)
Query: 607 RNMTSPIADFPAPPPY----SAVTPPPDAFSRGVSSPIAGPAQPPPWP--------QPAP 654
R +++P + P+PPP S +PP + + P+A P P P P +P P
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Query: 655 WSQP 658
++P
Sbjct: 4964 RARP 4967
Score = 30.4 bits (67), Expect = 9.6
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 10/66 (15%)
Query: 598 QPATPFSPTRNMTS-PIADFPAPPPYSAVTPPPDAFSRGVSSP-----IAGPAQP---PP 648
+P T S T N+++ + APPP +PPP + +SP + P +P PP
Sbjct: 4887 EPPTQHSYTYNVSNLDVRQLSAPPPEEP-SPPPSPLAPSPASPPTEPLVELPTEPLAEPP 4945
Query: 649 WPQPAP 654
P P P
Sbjct: 4946 VPSPLP 4951
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 71.2 bits (173), Expect = 5e-12
Identities = 47/169 (27%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
I + G PWGFRL GGK+ +QPL ++++ SKA+ + LC GD + +I+G +++T+ E
Sbjct: 6 IDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++ TD+L + + R + L++E E K + + L I A
Sbjct: 66 AQNRIKGCTDNLTLTVARSEHKVWSPLVTE-EGKRHPYKMNLASEPQEVLHIGSAHNRSA 124
Query: 129 TEFFLAPV-KTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRG 176
F +P T + NQ + P AG E ++ A + + G
Sbjct: 125 MPFTASPASSTTARVITNQYNNP--AGLYSSENISNFNNALESKTAASG 171
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 71.2 bits (173), Expect = 5e-12
Identities = 150/602 (24%), Positives = 204/602 (33%), Gaps = 107/602 (17%)
Query: 518 PSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGT-SET 576
P+ + A+ T + T +Y S S + VS P + G +G +
Sbjct: 771 PTEDSGASATASSKGTLTY---------LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI 821
Query: 577 ANIQRMV-PMNRTAKP-----FPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPD 630
N+ V P+ + P F GS + PAT SPT P + AP P SAVTP
Sbjct: 822 GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT-----PPSPKGAPTP-SAVTP--- 872
Query: 631 AFSRGVSSPIAGPAQPP-------PWPQ-----PAPWSQPAFYDSSERIASRDERISVPA 678
+GV+ P P + P P+P+ PAP PA +S +S + + PA
Sbjct: 873 LSPKGVTLP---PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS---SSPKKARATPA 926
Query: 679 KRTGILQEAKRRSTTKPMFTFKEPK---VSPNPELLSLLQNSEGKRGTGAGGDSGPEEDY 735
+ + + + T P T PK +P+P+ T GP
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA-----PTPPAATPPSPKGGP---- 977
Query: 736 LSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTS 795
+ S K PP A P+ K + P +P P V P P P +
Sbjct: 978 -----------ATPSPKGAPTPPAATPPSPKGGPATP-SPKGAPTPPAVTPPSPKGSPAA 1025
Query: 796 NP-SKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAV 854
P KG S+ A P P PA+T G P A + S PK +TP++
Sbjct: 1026 TPFPKG--ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS----PKGGPATPSLK-- 1077
Query: 855 QPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYS 914
GA P P G + + + M A P+ PA+ S
Sbjct: 1078 --GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135
Query: 915 --SNVRAPPP--VAYNPIHSPSYPLAAL--------KSQPSAAQPSKMGKKKGKKPLNAL 962
+ PPP P +P P L + P+A PS G P A
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 963 DVMKHQPYQLNASLFT-----------FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPV 1011
P L T PP K GL S A A PP P
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP---KGAPTTPAATPPSP- 1251
Query: 1012 NAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVP-VGIPTSPKQESASSSYFVAP 1070
P + PA T P A+ P +P P V P SPK A+S AP
Sbjct: 1252 -KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 1071 RP 1072
P
Sbjct: 1311 TP 1312
Score = 67.0 bits (162), Expect = 9e-11
Identities = 144/569 (25%), Positives = 195/569 (34%), Gaps = 111/569 (19%)
Query: 591 PFPGSVNQP-------ATPFSPTRNMTSPIADFPAPPPYSAVTP----PPDAFSRGVSSP 639
P P +V P ATPF P T P A P+P A TP P + + SP
Sbjct: 1009 PTPPAVTPPSPKGSPAATPF-PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 640 IAGPA--------QPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRS 691
GPA PP P+P PA S + A + P+ + G+ + +
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPA--TPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125
Query: 692 TTKPMFTFKEPK---VSPNPE---LLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNF 745
T P T PK +P P+ K G G +
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 746 MQSSSAKQKTPPPVAPKPAVKSSSSQP----------VTPVSP-----VWSPGVAPTQPP 790
+ + S K P A P+ K + P TP SP SP APT P
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245
Query: 791 AFPTSNPSKGTVVSSIKIAQPSYPPARPASTLN--VAGPFKG-PQAAVASQNYTPK--PT 845
A P S P G K A P+ P A P S P KG P AV + +PK P
Sbjct: 1246 ATPPS-PKGGPATPPPKGA-PTPPAATPPSLKGGLATPPHKGAPNPAVVTPP-SPKGGPA 1302
Query: 846 VSTPTVNAVQPGAVGPSNE-LPGM-SGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSP 903
S P P A PS + PG +GA T A +
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGA-----------------PTPPAVTPPSPKG 1345
Query: 904 TPSLPASWKYS-------SNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGK 956
TP+LPA+ S S+ P P A P H + + A PS G
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405
Query: 957 KPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAA-- 1014
V+ P + A+ P ++G S + +L P +A
Sbjct: 1406 A------VIPLSPKKAPAT------PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
Query: 1015 -SPTNVQASSVYSVPAYTSP-------PSFFAEASSP--VSASPVPVG-------IPTSP 1057
P + ++PA T P P A +SSP A+P P+G IP+SP
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
Query: 1058 KQESASSSYF---VAPRPKFSAKKSGVTI 1083
K+ A+ S +AP +KK+ T+
Sbjct: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATL 1542
Score = 66.6 bits (161), Expect = 1e-10
Identities = 137/521 (26%), Positives = 175/521 (33%), Gaps = 74/521 (14%)
Query: 566 QQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAV 625
Q S TS + R P K P S + P P SP P P A
Sbjct: 907 QAPALSMTSSSPKKARATP---APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
Query: 626 TPP---PDAFSRGVSSPI-AGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPA-KR 680
TPP P + G ++P G PP P+P PA S + A ++ P+ K
Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA--TPSPKGAPTPPAVTPPSPKG 1021
Query: 681 TGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGA 740
+ + ++T P T PK SP L +G T A P+ G
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPL-----PKGAPTTPAATLPSPK------GG 1070
Query: 741 EACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800
A + S K PP A P+ K P TP SP AP P A P S KG
Sbjct: 1071 PA-----TPSLKGAPTPPAATPPSPKGG---PATP-----SPKGAPMPPAATPPS--PKG 1115
Query: 801 TVVSSIKIAQPSYPPARPASTLN--VAGPFKGPQAAVASQNYTPKPTVSTPTVNA--VQP 856
+ + P+ P A P S P KG A+ +PK ++TP P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 857 GAVGPSNE--LPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSL--PASWK 912
A PS + L S +GA AA SP L P+
Sbjct: 1176 AATPPSPKGGLATPSPKGAP-------------------TTPAATPPSPKGGLATPSPKG 1216
Query: 913 YSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQL 972
+ A PP + +PS P A + P+A PS G P A P L
Sbjct: 1217 APTTPAATPPSPKGGLATPS-PKGA-PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
Query: 973 NASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTS 1032
L T PP G P + V S PP+ A +P S P T
Sbjct: 1275 KGGLAT--PP--HKGAPNPAVVTPPSPKGGPATSPPK--GAPTPPAATPPSPKGSPG-TP 1327
Query: 1033 PPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPK 1073
PP + P P P G PT P +S P K
Sbjct: 1328 PPK--GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366
Score = 63.5 bits (153), Expect = 1e-09
Identities = 124/527 (23%), Positives = 175/527 (33%), Gaps = 92/527 (17%)
Query: 602 PFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPW---PQPAPWS-- 656
P T + + + P P +AV P A S + GP PPP PQ P S
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 657 -QPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSP--NPELLSL 713
Q + + S IAS + P +G A T TF + P +P L+L
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSG---TALPLGTAPEAPTFLPNLIGPPISPAALAL 118
Query: 714 LQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSS---- 769
G S P L+L A A + +Q SSA P AV S
Sbjct: 119 ASPMIAPTLKGTPSSSAP----LALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVIT 174
Query: 770 -SQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVS-----------SIKIAQPSYPPAR 817
S P+ P P + P++ P PS +VS SI+ S P
Sbjct: 175 LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT 234
Query: 818 PASTLNVAGP---------------------FKGPQAAVASQNYTPKPTVSTPTVNAVQP 856
P +TL +A P KGP + A+ + + T S P V + Q
Sbjct: 235 PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLS---TQSLPVVTSSQK 291
Query: 857 GAVGPSNELPGMSGRGAQLFAKRQS-------------------RMEKYVVDSDTVQAHA 897
A GP+ G+ L QS ++ VD + A
Sbjct: 292 TA-GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASY 350
Query: 898 ARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKK 957
+S P LP S N P VA P+ +PS PS
Sbjct: 351 PSQRSVIPPLP-----SRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPS--------- 396
Query: 958 PLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPT 1017
+L+V SL P+A P + + V+S + AA+PT
Sbjct: 397 --GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPT 454
Query: 1018 NVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASS 1064
+ P +S P E +SP + PV P P + A++
Sbjct: 455 TTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA-PKEPSTQVATT 500
Score = 63.5 bits (153), Expect = 1e-09
Identities = 125/552 (22%), Positives = 178/552 (32%), Gaps = 118/552 (21%)
Query: 582 MVPMNRTAKPFPGSVNQP--ATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSP 639
M P P G P P +P SP PPP A T P + SP
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP----AATPPSP 1159
Query: 640 IAGPAQPPPWPQPA------PWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTT 693
G A PPP P P + S + A + P+ + G+ + + + T
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219
Query: 694 KPMFTFKEPK---VSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSS 750
P T PK +P+P+ G T A P+ G A +
Sbjct: 1220 TPAATPPSPKGGLATPSPK---------GAPTTPAATPPSPK------GGPA-----TPP 1259
Query: 751 AKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVA-PTQPPAFPTSNPSKGTVVSSIKIA 809
K PP A P++K + P +P +P V P P P ++P KG
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAP--NPAVVTPPSPKGGPATSPPKGA-------- 1309
Query: 810 QPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMS 869
P+ P A P S G P+ A TP TPT+ A P + G
Sbjct: 1310 -PTPPAATPPSPKGSPGT-PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT----- 1362
Query: 870 GRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPT-----PSLPASWKYSSNVRAPPPVA 924
S E + T A +P P++P+ + +P +
Sbjct: 1363 ----------PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP---KGDPTSPAVIP 1409
Query: 925 YNPIHSPSYPL----AALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNA----SL 976
+P +P+ P+ AA S+ P+ K P A K P ++ +L
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP--ATSAPKGGPATPSSKGDPTL 1467
Query: 977 FTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTS---- 1032
PP K+ P S+ K P P+ A + V SS VPA S
Sbjct: 1468 PAVTPPSPKE--PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 1033 ------------------------PPSFFAEASSPVSASPVPVGIPTSPKQESAS----- 1063
PP+ + A P P P +P + AS
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
Query: 1064 --SSYFVAPRPK 1073
S+Y AP PK
Sbjct: 1586 TPSTYKGAPSPK 1597
Score = 59.3 bits (142), Expect = 2e-08
Identities = 114/504 (22%), Positives = 162/504 (32%), Gaps = 81/504 (16%)
Query: 584 PMNRTAKPFP-GSVNQPA-TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIA 641
P A P P G+ PA TP SP + +P P A TPP SP
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK--GAPTTPAATPP---------SPKG 1253
Query: 642 GPAQPPPWPQPAPWSQPAFYDSS---------ERIASRDERISVPAKRTGILQEAKRRST 692
GPA PPP P P PA S + A ++ P+ + G + +
Sbjct: 1254 GPATPPPKGAPTP---PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 693 TKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAK 752
T P T PK SP GT + + + +++
Sbjct: 1311 TPPAATPPSPKGSP---------------GTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 753 QKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIA-QP 811
K P P+ K + P S P + P P P KG S I P
Sbjct: 1356 SKGGPTT---PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 812 SYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNE----LPG 867
PA P + A P KG A TP P +A + G PS++ LP
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPA---VTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
Query: 868 MSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYS-SNVRAPPPVAYN 926
++ K ++ S +A A A P+LPA S V A P +
Sbjct: 1470 VTPPSP----KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 927 PIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKD 986
PI P A L S+ + P+ + K+ P T P
Sbjct: 1526 PIA----PTATLLSKKT---PATLAPKEALIP----------------PAMTVPSPKKTP 1562
Query: 987 GLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSA 1046
+P + K+A P V ++ + +P + PS + P
Sbjct: 1563 AIPTPKEAPATPS--SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Query: 1047 SPVPVGIPTSPKQESASSSYFVAP 1070
P P P +P + +S V P
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTP 1644
Score = 53.1 bits (126), Expect = 1e-06
Identities = 122/520 (23%), Positives = 177/520 (34%), Gaps = 100/520 (19%)
Query: 593 PGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQP 652
P S P TP S + +P A P+ A+TPP + SP P P P
Sbjct: 1354 PSSKGGPTTPSS--KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL- 1410
Query: 653 APWSQPAFYDSSERIASRDERISVP---------------AKRTGILQEAKRRSTTKPMF 697
+P PA + E A+ + P A + G + + T P
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 698 TFKEPKVSPNPELLSLLQNSEGKRGTGAGGD---------SGPEEDYLSLGAEACNFMQS 748
T PK P P+ ++ + + T A S P+E + + +
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530
Query: 749 SSA-KQKTPPPVAPK----------------PAVKSSSSQPVTPVSPVWS--PGVAPTQP 789
++ +KTP +APK PA+ + P TP S S P V P+
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
Query: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
P+ P + + ++ P P PA T P KGP TP P TP
Sbjct: 1591 KGAPS--PKELLIPPAVTSPSPKEAPTPPAVT--PPSPEKGPA--------TPAPK-GTP 1637
Query: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPA 909
T V P ++ S P A + K + + + A P P
Sbjct: 1638 TSPPVTPSSLKDSPTSP------ASVTCKMGATVPQ------------ASKGLPAKKGPT 1679
Query: 910 SWKYSSNVRAP--PPVAYNPIH-SPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMK 966
+ K AP P+ P P ++ S P PS KG PL+ +
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG--PLSTV---- 1733
Query: 967 HQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNV-QASSVY 1025
A L Q +K + +S LA ++ P+ AA+ V
Sbjct: 1734 -----APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
Query: 1026 SVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSS 1065
SV A SPP S P++ SPVP PKQ+ SS
Sbjct: 1789 SVSAAPSPP-----VSLPLAPSPVPT---LPPKQQFLPSS 1820
Score = 52.0 bits (123), Expect = 3e-06
Identities = 123/536 (22%), Positives = 169/536 (31%), Gaps = 83/536 (15%)
Query: 602 PFSPTRNMTSPIADFPAPP--PYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPA 659
P PT + P+A P P + + P+ + + P+ PP P
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPE-----IPKSVPSPSLPPAGTPPGTKKVDG 753
Query: 660 FYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEP---KVSPNPELLSLLQN 716
+S P + +G A + T + P VSP + +
Sbjct: 754 ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG 813
Query: 717 SEGKRGTGAGGDSGP----EEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQP 772
S G T G S P E +L + + + S A +P P +PK A S+ P
Sbjct: 814 SAGP-DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTP 872
Query: 773 VTPVSPVWSPGVAPT----------QPPAFP-----------TSNPSKGTVVSSIK---- 807
++P P PT + PA P +S+P K + K
Sbjct: 873 LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932
Query: 808 IAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQP------GAVGP 861
P P PA+T P GP A S + P P +TP P GA P
Sbjct: 933 SPSPKGAPTPPAAT--PPSPKGGP--ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988
Query: 862 SNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAAR-----AQSPTPSLPASWKYSSN 916
P G + + + V + AA A +P + P S K S
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 917 V--------RAPPPVAYNPIHSPSYP-LAALKSQPSAAQPSKMGKKKGKKPLNALDVMKH 967
P +P P+ P L + P+A PS G P A
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108
Query: 968 QPYQLNASLFT-----------FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNA-AS 1015
P L T PP K GL ++ A A PP P A+
Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPSPKGGLAT 1165
Query: 1016 PTNVQASSVYSVPAYTSP-PSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAP 1070
P A + PA T P P SP A P P SPK A+ S AP
Sbjct: 1166 PPPKGAP---TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218
Score = 47.4 bits (111), Expect = 8e-05
Identities = 87/340 (25%), Positives = 117/340 (34%), Gaps = 80/340 (23%)
Query: 583 VPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFP-----APPPYSAVTPP--------- 628
VP + P PATP S + +SP A P AP P + PP
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSS--KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612
Query: 629 -PDAFSRGVSSPIAGPAQPPP--WPQPAPWSQPAFYDSSERIASRDERIS---------V 676
P + SP GPA P P P P + + DS AS ++ +
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672
Query: 677 PAKR----------------TGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
PAK+ T I+ R+ + P + P+P S S+G
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP---SAKNGSKGP 1729
Query: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSS-------AKQKTP------PPVAPKPAVKS 767
T A P + S A+ + S +K TP V PKP S
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESAS 1789
Query: 768 SSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYP----------PAR 817
S+ P PVS +P PT PP S G V+ S PS P P
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLES-----PSKPLAPADEDELLPLI 1844
Query: 818 PASTLNVAGPFKGPQAAVASQNYTPKPT-VSTPTVNAVQP 856
P ++ PF+ +V TPK + PT +A QP
Sbjct: 1845 PPEPISGGVPFQ----SVLVNMPTPKSAGIPVPTPSAKQP 1880
Score = 37.0 bits (84), Expect = 0.10
Identities = 101/464 (21%), Positives = 164/464 (35%), Gaps = 64/464 (13%)
Query: 637 SSPIAGPAQPPPWP-----QPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRS 691
S AGP PP +P AP Q +F + +S P +T + S
Sbjct: 289 SQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDH----S 344
Query: 692 TTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGG-DSGPEEDYLSLGAEACNFMQSSS 750
+T + + + P P ++ + A D GP ++ + C+ S S
Sbjct: 345 STGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPS----TISSITCS--PSGS 398
Query: 751 AKQKTPPPVAPKPAVKSSSSQPVT---------PVSPVWSPGVAPTQP---PAFPTSNPS 798
T ++P ++ SS T PVS V + + T P A PT+
Sbjct: 399 LNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE 458
Query: 799 KGTVVSSIKIAQPSYPP--ARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQP 856
T VS PP + P S + P A VA + P V+T V P
Sbjct: 459 VATCVS---------PPMSSGPISNIEPTSPAALVMAPVAPKE--PSTQVATTLRIPVSP 507
Query: 857 GAVGPSN--ELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYS 914
P + LP S + K+ D A+ +P A
Sbjct: 508 PLPDPEDLKNLPS-------------SVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTK 554
Query: 915 SNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQ--PYQL 972
+ P V P +SPS+ + + + + + KK +PL P +
Sbjct: 555 KDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGV 614
Query: 973 NASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTS 1032
N+S + D+ G P + + S+L + + P+ +A P V ++ YT+
Sbjct: 615 NSSASVIKT-DSYAG-PDSAGPLLKSSL-ITPTVAAFPLESADPAGVAPTTAKGTSTYTT 671
Query: 1033 PPSFFAEASSPVSASPVPV---GIPTSPKQESASSSYFVAPRPK 1073
S F E + ++ PV + T P +AS + VAP P+
Sbjct: 672 TASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQ 715
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 69.3 bits (168), Expect = 2e-11
Identities = 113/466 (24%), Positives = 162/466 (34%), Gaps = 88/466 (18%)
Query: 621 PYSAVTPPPDAFSRGVSSPIAGPAQPPPW----PQPAPWSQPAFYDSSERIASRDERISV 676
P + PPD S + +P++ PA PP P +P S P + ++S
Sbjct: 444 PSRPASTPPD--SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Query: 677 PAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYL 736
+ I+ + +S+ P P P L +L + T + + P +
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561
Query: 737 SLGAEACNFMQSSSAKQKTPPPVAPK----------PAVKSSSSQ--PVTPVSPVWSP-- 782
A +Q+ + TPPP P PA+ S Q P P+SP+ +P
Sbjct: 562 PCPAPCP--LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Query: 783 ------GVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVA 836
+ P Q P P ++P +S + P P A L PF P +
Sbjct: 620 QAPPXLALPPLQAPPSPPASPP----LSPLATPSPQAPNALAVHLLQA--PFSPPPSPPV 673
Query: 837 SQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAH 896
++P P V P A PS P ++ Q+
Sbjct: 674 QAPFSP------PASPPVSPSATPPSQAPPSLAAPPLQV--------------------- 706
Query: 897 AARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGK 956
SP S P S + +APPP+A P+ P P A+ PSA P ++
Sbjct: 707 ---PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
Query: 957 KPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVN--AA 1014
P L V P L S PP A L A QALP P +
Sbjct: 764 PP---LQVPPSPPASLPMSPLAKPPPQAPPAL----------ATPPLQALPSPPASFPGQ 810
Query: 1015 SPTNVQASSVYSVPAYTSPPSFFAEASSPVSASP---VPVGIPTSP 1057
+P + AS S P T PP + PV A+P VP P SP
Sbjct: 811 APFSPSASLPMS-PLATPPPQ-----APPVLAAPLLQVPPSPPASP 850
Score = 63.9 bits (154), Expect = 8e-10
Identities = 90/372 (24%), Positives = 126/372 (33%), Gaps = 40/372 (10%)
Query: 584 PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGP 643
P+ P S+ P P +P + P+ P+PP TPPP A P+ P
Sbjct: 575 PLTTPPPETPSSIATPP-PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
Query: 644 AQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPK 703
PP P +P + P+ + A +LQ + P+ P
Sbjct: 634 PSPPASPPLSPLATPSPQAPN-------------ALAVHLLQAPFSPPPSPPVQAPFSPP 680
Query: 704 VSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKP 763
SP P S S+ A P S + TPPP AP P
Sbjct: 681 ASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPAS----------PPMSPSATPPPQAPPP 729
Query: 764 -AVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPAR-PAST 821
A P P SP SP P PP P ++++ + P PPA P S
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATP--PPRVP-------PLLAAPPLQVPPSPPASLPMSP 780
Query: 822 LNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQS 881
L P P A P P S P P A P + L + + A
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840
Query: 882 RMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRA---PPPVAYNPIHSPSYPLAAL 938
++ S T+QA R +P P S + A PPP + +P + S P A
Sbjct: 841 QVPPSPPASPTLQA-PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
Query: 939 KSQPSAAQPSKM 950
S + + P ++
Sbjct: 900 HSSSATSTPEEL 911
Score = 57.8 bits (138), Expect = 6e-08
Identities = 146/631 (23%), Positives = 212/631 (33%), Gaps = 90/631 (14%)
Query: 486 DTTGKGALMFAKRRERMDQITAQKEEDKVGGTPS----REQDAAQTD-GLRTTTSYQRKE 540
+T +G A +R + + GTPS R AA T+ GL R
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 541 EESVRTQSSVSK----SYIEVSHGLGHVPQQNGFSGTSETANIQRMV-PMNRTAKPFPGS 595
+ + SVS S E S P G + ++ P++ A+ P +
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 596 VNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPW 655
P P P++ P P A+ PP R ++P GP P P+P
Sbjct: 260 RGTPRAPAHPSQ---------PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 656 SQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQ 715
A R + + P T P P P+P LQ
Sbjct: 311 GTKA------RPVPPPDNAATPLPAT---------LPPSPPLATPLPLAPPSPSAPPSLQ 355
Query: 716 NSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTP 775
T P + S+ MQ+ + Q T PP+ ++ S S Q P
Sbjct: 356 TLPSPPAT------PPSQAPPSMTTPP---MQAPPSLQ-TIPPIQVPHSLTSPSLQ--AP 403
Query: 776 VSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSY-PPARPASTLNVAGPFKGPQAA 834
SP+ + T PT + + S + Q S P+RPAST + P + P +
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 835 VASQNYTPKPTVSTPTVNAV-QPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTV 893
AS P T +P V+ + P + P L ++ Q+ + ++
Sbjct: 464 PAS---PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP------QAPLSSLIMPPLET 514
Query: 894 QAHAA--RAQSPTPSLPASWKYSSNVRAPPPV--AYNPIHSPSY---------PLAALKS 940
Q+ A Q+P SL + APPP+ A P+ +P PL A S
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574
Query: 941 QPSAAQPSKMGKKKGKKPLNALDVMKHQPYQ----LNASLFTFQPPDAKDGLPQKSSVKV 996
P P + P A + P Q S PP A P ++
Sbjct: 575 -PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA----PPXLALPP 629
Query: 997 NSALAMKQALPP-RPVNAASPTNVQASSVYSVPAYTSPP-------SFFAEASSPVSASP 1048
A A PP P+ SP A +V+ + A SPP F AS PVS S
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 689
Query: 1049 VPVGIPTSPKQESASSSYFVAPRPKFSAKKS 1079
P P+ A+ V P P S S
Sbjct: 690 TP---PSQAPPSLAAPPLQVPPSPPASPPMS 717
Score = 57.4 bits (137), Expect = 7e-08
Identities = 120/544 (22%), Positives = 188/544 (34%), Gaps = 100/544 (18%)
Query: 595 SVNQPATPFSPTRNMTSPIADFPAPPPYSAV---TPPPDAFSRGVSSPIAGPAQPPPWPQ 651
++ + A PTR+ + + + PP S PP S G P++ P + +
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---PVSSPGRASGTTR 125
Query: 652 PAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRST------------------- 692
P P Q S+E +R + P KR+ + A+R ++
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAP-KRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 693 -------TKPMFTFKEPKVSPNPELLSLLQNS-------EGKRGTGAGGDSGPEEDYLSL 738
P + P P + S ++S +R + GG P LS
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 739 GAEACNF-------------------------MQSSSAKQKTPPPVAPKPAVKSSSSQPV 773
A + +Q+ Q TPP PA+ SS P+
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 774 TPVSPVWSPGVAPTQPP-----AFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPF 828
SP + P PP P + P + + + +A PS P+ P S + P
Sbjct: 305 ATPSPSGTK-ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS--PSAPPSLQTLPSPP 361
Query: 829 KGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVV 888
P + TP P + P++ + P V S P + + L S +
Sbjct: 362 ATPPSQAPPSMTTP-PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL--ALSSLQATTSL 418
Query: 889 DSDTVQA-HAARAQSPTPSLPASWKYSSNVRAPP--PVAYNPIHSPSYPLAALKSQPSAA 945
S T+QA H+ SP + + S PP P P+ P+ P P+
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV- 477
Query: 946 QPSKMGKKKGKKPLNAL-DVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQ 1004
S + PL AL + H P +SL PP L +SS+ S
Sbjct: 478 --SPLSSPLTIHPLQALSSLASHSPQAPLSSL--IMPP-----LETQSSLAPPSLQTPPA 528
Query: 1005 ALPPRPV----NAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE 1060
+L P+ + A P AS+ + P +PP A P+ A P P+ T+P E
Sbjct: 529 SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP---CPAPCPLQAPPSPL---TTPPPE 582
Query: 1061 SASS 1064
+ SS
Sbjct: 583 TPSS 586
Score = 30.8 bits (68), Expect = 7.3
Identities = 69/320 (21%), Positives = 113/320 (35%), Gaps = 41/320 (12%)
Query: 754 KTPPPVAPKPAVKSSSSQPVTPVS--PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQP 811
+ P + P+P PVTP + + + G +P A T+ S P
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA----P 75
Query: 812 SYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGR 871
P R A T + P P A+ + P S V++ PG + + +
Sbjct: 76 RAGPTRSAGTSS-RNPASRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRPGPLGQK 132
Query: 872 GAQLFAKRQSRMEKYVV--DSDTVQAHAARAQS-PTPSLPA------SWKYSSNVRAPPP 922
G ++ A+ K + A A R S PTP P+ S + V P P
Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 923 VAYN----PIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFT 978
P P +++ S+ S +PS +++ P + + L++S
Sbjct: 193 APSARPRPPTEGPRKSVSSA-SEHSTTEPSPAARRR---PSAGGGLQRPASRSLSSSATP 248
Query: 979 FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFA 1038
P A+ G + + + A P +P P +QA P T P A
Sbjct: 249 LSSP-ARSGPSARGTPRA-------PAHPSQP----KPKGLQA---LRPPQVTPPRKDAA 293
Query: 1039 EASSPVSASPVPVGIPTSPK 1058
A P+S+SP+ P+ K
Sbjct: 294 PALGPLSSSPLATPSPSGTK 313
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 68.9 bits (167), Expect = 2e-11
Identities = 51/183 (27%), Positives = 82/183 (44%), Gaps = 40/183 (21%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++ T SL M ++R S+ E +Q +P + C
Sbjct: 66 AQNKIKGCTGSLNMTLQRASAAPKP--------------------EPVPVQ-KPTVTSVC 104
Query: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGP----------SYQRAPQMPDSQRGRV 178
+E T LAE QR G G K++ GP + P D+ + R+
Sbjct: 105 SE-------TSQELAEGQRRGSQ--GDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRL 155
Query: 179 AEE 181
E+
Sbjct: 156 IED 158
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 65.9 bits (159), Expect = 2e-10
Identities = 120/501 (23%), Positives = 175/501 (34%), Gaps = 53/501 (10%)
Query: 588 TAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPP 647
T+ P PG+ P+ + P P P + PP + + VSS
Sbjct: 164 TSGPTPGT---PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS---ASEHST 217
Query: 648 PWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPN 707
P PA +P+ +R ASR S+ + T + A+ + + P
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASR----SLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273
Query: 708 PELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKS 767
P+ L L+ + T D+ P LS A S++ + + PP + P S
Sbjct: 274 PKGLQALRPPQV---TPPRKDAAPALGPLSSSPLATP-SPSAALQSQAPPTLPATPHSSS 329
Query: 768 SSSQPVTPVSPVWSPGVAPTQPPAF------PTSNPSKGTVV--SSIKIAQPSYPPARPA 819
+ Q TP+ P+ P +P+ PP+ P + PS+ T S A S+ P+ P
Sbjct: 330 LTCQLATPL-PLAPP--SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386
Query: 820 STLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKR 879
S L P P A+ P P S P P P+ A
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN------------ALAVH 434
Query: 880 QSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALK 939
+ S VQA SP S P S + +APP +A P+ P P A+
Sbjct: 435 LLQAPFSPPPSPPVQAPF----SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 490
Query: 940 SQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQ-KSSVKVNS 998
PSA P + PL + P Q +L T PP LP +S +
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQ----LAKPPPQAPPALAT--PP--LQALPSPPASFPGQA 542
Query: 999 ALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPK 1058
+ +LP P+ P QA V + P PPS A + P G TS
Sbjct: 543 PFSPSASLPMSPLATPPP---QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 1059 QESASSSYFVAPRPKFSAKKS 1079
+ + P P S S
Sbjct: 600 GPRLTLALAPGPPPPPSRSPS 620
Score = 57.0 bits (136), Expect = 1e-07
Identities = 108/479 (22%), Positives = 165/479 (34%), Gaps = 51/479 (10%)
Query: 595 SVNQPATPFSPTRNMTSPIADFPAPPPYSAV---TPPPDAFSRGVSSPIAGPAQPPPWPQ 651
++ + A PTR+ + + + PP S PP S G P++ P + +
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---PVSSPGRASGTTR 125
Query: 652 PAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELL 711
P P Q S+E +R + P + L RR T+ P +P+P +
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAP--KRSALSAGARRDTSGP------TPGTPSPAMA 177
Query: 712 SLLQNSEGKRGTGAGGDS--------GPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKP 763
+ + + G S GP + S + ++ ++ + +P
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 764 AVKSSSSQPVTPVSPVWSPGVAPTQP--PAFPTSNPSKGTVVSSIKIAQPSYPPARPAST 821
A +S SS SP S A P PA P+ KG P A PA
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
Query: 822 LNVAGPFKGPQAAVASQNYTPKPTVSTP-----TVNAVQPGAVGPSNELPGMSGRGAQLF 876
+ P P + A Q+ P +TP T P + P + S +
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357
Query: 877 AKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLA 936
+ S T+QA S PS P S + +APP +A P+ +P P A
Sbjct: 358 PATPPSQATTSLGSPTLQA----THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413
Query: 937 ALKSQPSAAQPSKMGKKKGKKPLNALDV-MKHQPYQLNASLFTFQPPDAKDGLPQKSSVK 995
+ P A PS NAL V + P+ S P P S
Sbjct: 414 SPPLSP-LATPSPQAP-------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
Query: 996 VNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIP 1054
S A PP V + P + S P+ T PP +A P++A P+ + P
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMS-----PSATPPP----QAPPPLAAPPLQLAKP 515
Score = 53.5 bits (127), Expect = 1e-06
Identities = 100/422 (23%), Positives = 145/422 (34%), Gaps = 60/422 (14%)
Query: 573 TSETANIQRMVPMNRTAKPFPGSV-NQPATPFSP-TRNMTSPIAD-----FPAPPPYSAV 625
T + A + P + +A P ++ + PATP S T ++ SP P+PP
Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390
Query: 626 TPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQ 685
TPPP A P+ P PP P +P + P+ + A +LQ
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN-------------ALAVHLLQ 437
Query: 686 EAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGG----DSGPEEDYLSLGA- 740
+ P+ P SP P S S+ A S P +S A
Sbjct: 438 APFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496
Query: 741 ---EACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPA------ 791
+A + + + PPP AP PA+ + Q + P P PG AP P A
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQAL-PSPPASFPGQAPFSPSASLPMSP 554
Query: 792 FPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYT---------- 841
T P V+++ + P PPA P P GP +V+ T
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614
Query: 842 ----PKPTVSTPTVNAVQPGAVGPSNELPGM-SGRGAQLFAKRQSRMEKYVVDSDTVQAH 896
P T+S P + A EL G SG A D++ H
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP-------DAELAACH 667
Query: 897 AARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGK 956
A A S P+ P +++ + P P A P + P +A P+ G
Sbjct: 668 PA-AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726
Query: 957 KP 958
P
Sbjct: 727 SP 728
Score = 37.4 bits (85), Expect = 0.078
Identities = 79/337 (23%), Positives = 116/337 (34%), Gaps = 71/337 (21%)
Query: 574 SETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAP---PPYSAVTPPPD 630
S +A P + A P + PA+P P +P P P PP PPP
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
Query: 631 AFSRGVSSPI-AGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISV------------P 677
A + P+ A P+ P +P AP+S A S + V P
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578
Query: 678 AKRTGILQEAKRRSTTKPMFTFKEPKVS-------PNPELLSLLQNSEGK--RGTGAGGD 728
A T LQ +R T P + P+++ P P S G G +
Sbjct: 579 ASPT--LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 636
Query: 729 SGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQ 788
S PEE ++ + + +P P + ++ P WS G AP
Sbjct: 637 STPEE------------LRGYDSGPEGGAAASPPPDAELAACHPA-----AWSRGPAP-- 677
Query: 789 PPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVST 848
P AF P P P +T GP G + + T P +T
Sbjct: 678 PLAFR---------------GAPGAPLPWPPAT----GP--GSADGLCTIYETEGPESAT 716
Query: 849 PTVNAVQPG-AVGPS-NELPGMSGRGAQLFAKRQSRM 883
P A+ PG + G S + +G GA + +Q+R+
Sbjct: 717 PAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 753
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 65.5 bits (158), Expect = 3e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 30/160 (18%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++ T SL M ++R S+ E +Q +P + C
Sbjct: 66 AQNKIKGCTGSLNMTLQRASAAPKP--------------------EPVPVQ-KPTVTSVC 104
Query: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAP 168
+E T LAE QR G G K++ G + P
Sbjct: 105 SE-------TSQELAEGQRRGSQ--GDSKQQNGKIPPKRP 135
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 65.5 bits (158), Expect = 3e-10
Identities = 139/559 (24%), Positives = 192/559 (34%), Gaps = 137/559 (24%)
Query: 542 ESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPAT 601
ES S+ S S + + GHV Q+ S A +R + ++K S+N+P T
Sbjct: 545 ESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEA-WKRGTQLEESSKARMESMNRPYT 603
Query: 602 ----PFSPTRNMTSPI-ADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWS 656
P SP + +P A P+PP PPP P PPP P P P
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPP-----LPPP-------------PPPPPPPPPPPPPP 645
Query: 657 QPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQN 716
P +P+ Q A + PMF ++ LQN
Sbjct: 646 PP----------------PLPS------QSAPSAGSAAPMFV--------KYSTITRLQN 675
Query: 717 SEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQK---------TPPPVAPKPAVKS 767
+ G + P MQS S K + PPP P P
Sbjct: 676 ASQHSGALFKPPTPP-------------VMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG 722
Query: 768 SSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSI-KIAQPSYPPARPASTLNVAG 826
S+ + P AP+ P P K V I ++A P+ PP P +
Sbjct: 723 SAMAQLKPAP------CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP-----IPA 771
Query: 827 PFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKY 886
P PQA P PT ST TV V A P+ P + K+ + Y
Sbjct: 772 PLP-PQAPPKPLVTIPAPT-STKTVAPVVTQAAPPTPTPPVPPAK------KQPAFPASY 823
Query: 887 VVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLA---------- 936
+ S P P+LP K S PPP +P+ S +A
Sbjct: 824 IPPSPPTPP----VPVPPPTLP---KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 937 ALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKV 996
A++SQP P+ + + P K QP + F PP P+ S V
Sbjct: 877 AMESQPLKPVPANVAP---QSPPAVKAKPKWQPSSIPVPSPDFPPPP-----PESSLVFP 928
Query: 997 NSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTS 1056
+ A PP P ASPT ++ SP ++ SSP P P +
Sbjct: 929 PPPPSPVPAPPPPPPPTASPTPDKSG---------SPGKKTSKTSSPGGKKP-----PPT 974
Query: 1057 PKQESA--SSSYFVAPRPK 1073
P++ S+ SSS P PK
Sbjct: 975 PQRNSSIKSSSGAEHPEPK 993
Score = 63.9 bits (154), Expect = 8e-10
Identities = 119/528 (22%), Positives = 169/528 (32%), Gaps = 66/528 (12%)
Query: 574 SETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFS 633
S++ Q +VP N P P P TP S + P P+ P +SA PP
Sbjct: 694 SQSVKPQILVPPNGVVPP-PPPPPPPPTPGSAMAQL-KPAPCAPSLPQFSAPPPPLKIHQ 751
Query: 634 RGVSSPIAGPAQPPPWPQPAPWSQPAF--------YDSSERIASRDERISVPAKRTGILQ 685
+ +A P PPP P PAP A +S + + + P T +
Sbjct: 752 VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVP 811
Query: 686 EAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNF 745
AK++ + P P P L + P LS
Sbjct: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK-------PPPSPLSPVPSVVKQ 864
Query: 746 MQSSSAKQKTPP-----PVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800
+ S TPP P+ P PA + S P P W P
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQP------------------ 906
Query: 801 TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVG 860
SSI + P +PP P S+L P P + V + P PT S + PG
Sbjct: 907 ---SSIPVPSPDFPPPPPESSLVFPPP---PPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960
Query: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAP 920
PG G+ +R S + S + H + SL + + + +P
Sbjct: 961 SKTSSPG--GKKPPPTPQRNSS-----IKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Query: 921 PPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPL---NALDVMKHQPYQLNASLF 977
P +P P S + + G K P+ D + P + S F
Sbjct: 1014 SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDF 1073
Query: 978 TFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPS-- 1035
PP+ + LP V S P V P SV P T P
Sbjct: 1074 PPPPPETELPLPPIEIPAVFSG----NTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRND 1129
Query: 1036 ----FFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKS 1079
AE S + + V +PTSPK + F+A + +KS
Sbjct: 1130 STRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKS 1177
Score = 52.4 bits (124), Expect = 2e-06
Identities = 72/328 (21%), Positives = 111/328 (33%), Gaps = 28/328 (8%)
Query: 757 PPVAPKPAV-----KSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQP 811
PP++P+P + S S P+ P P P P PP P + S + S+ +
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Query: 812 SYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGR 871
R + +G P Q+ + KP + P V P P PG S
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG-SAM 725
Query: 872 GAQLFAKRQSRMEKYVVDSDTVQ----AHAARAQSPTPSLPASWKYSSNVRAPPPVAYNP 927
A + ++ ++ H + PTP P PP A P
Sbjct: 726 AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP-----------PPIPAPLP 774
Query: 928 IHSPSYPLAALKSQPSAAQPSKMGKKKG-KKPLNALDVMKHQPYQLNASLFTFQPPDAKD 986
+P PL + + S + + + P + K QP AS PP
Sbjct: 775 PQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQP-AFPASYIPPSPPTPPV 833
Query: 987 GLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSA 1046
+P + K S A PP P++ Q +S + P +PP+ ++ PV A
Sbjct: 834 PVPPPTLPKQQSFCAKP---PPSPLSPVPSVVKQIASQFPPP--PTPPAMESQPLKPVPA 888
Query: 1047 SPVPVGIPTSPKQESASSSYFVAPRPKF 1074
+ P P + S P P F
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPDF 916
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 64.7 bits (156), Expect = 5e-10
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++S + +L + +++ I + + L + H Q PA T
Sbjct: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPH---------QKDPALDTNG 115
Query: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKV 188
+ +P + R+ P G+ E P++ A P +
Sbjct: 116 SLVAPSP-------SPEARASPGTPGT--PELRPTFSPAFSRPSA----------FSSLA 156
Query: 189 EAVQPGPV-VELQLSLSQERHKGASGPLVALPGAEKSK 225
EA PGP L+ S E + GP ALPG+ + +
Sbjct: 157 EASDPGPPRASLRAKTSPEGARDLLGP-KALPGSSQPR 193
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 64.7 bits (156), Expect = 5e-10
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++S + +L + +++ I + + L + H Q PA T
Sbjct: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPH---------QKDPALDTNG 115
Query: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKV 188
+ +P + R+ P G+ E P++ A P +
Sbjct: 116 SLVAPSP-------SPEARASPGTPGT--PELRPTFSPAFSRPSA----------FSSLA 156
Query: 189 EAVQPGPV-VELQLSLSQERHKGASGPLVALPGAEKSK 225
EA PGP L+ S E + GP ALPG+ + +
Sbjct: 157 EASDPGPPRASLRAKTSPEGARDLLGP-KALPGSSQPR 193
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 584 PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADF-PAPPPYSAVTPPPD---AFSRGVSSP 639
P T P P PA ++P SP+ + P+P P +P P+ A S S
Sbjct: 426 PTPYTPSPAPAYTPSPAPAYTP-----SPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG 480
Query: 640 IAGPAQPPPWPQPAPWSQ 657
A PA PPW +SQ
Sbjct: 481 PAEPASRPPWVTDDSFSQ 498
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/81 (38%), Positives = 51/81 (62%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSS 89
++ T SL M ++R S+
Sbjct: 66 AQNKIKGCTGSLNMTLQRASA 86
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/81 (38%), Positives = 51/81 (62%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSS 89
++ T SL M ++R S+
Sbjct: 66 AQNKIKGCTGSLNMTLQRASA 86
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 63.5 bits (153), Expect = 1e-09
Identities = 110/502 (21%), Positives = 175/502 (34%), Gaps = 74/502 (14%)
Query: 594 GSVNQPATPFSPTRNMTSPIADFPAPP-----PYSAVTPPPDAFSRGVSSPIA------- 641
G P P+ P R P A APP P ++ PP A + S +
Sbjct: 980 GDTGSPRKPW-PERRPPRPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTS 1038
Query: 642 -----GPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPM 696
P PP P PA + P + S D +S P + ++ + P+
Sbjct: 1039 EATSDAPDTSPPTPDPASRTNPDLI-----LTSPDFALSTPD--SSVVPALTPEPSPTPL 1091
Query: 697 FTF-KEPKVSPNP--ELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQ 753
T KE P+ E+ SL SE + D+ P+ D + + +S
Sbjct: 1092 PTLPKELTSDPSTPSEVTSLSPTSEQVPES----DTTPDLDTTPYSSTVSEYSRSPDPSP 1147
Query: 754 KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSY 813
P P P + + P+T ++P +P PT P PT+ P T+ S I P+
Sbjct: 1148 SPHPTTTPDPTM---APDPITTLNPTVTPHF-PTTP--HPTTTPHPTTITHSTMIPDPTT 1201
Query: 814 PPARPASTLN----VAGPFKGPQAAVASQ-NYTPKPTVSTPTVNAVQPGAVGPSNELPGM 868
P +P +T+ + P PQ Q TP T PT P + S +P
Sbjct: 1202 TP-QPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTP-HPTTITHSTMIPDP 1259
Query: 869 SGRGAQLFAKRQSRM-EKYVVDSDTVQAHAARAQSPT----PSL---PASWKYSSNV--- 917
+ + + M T H PT P++ P + Y +
Sbjct: 1260 TTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDP 1319
Query: 918 -RAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNA-LDVMKHQPYQLNAS 975
P P +P +P +L + S K L+ L P+ +
Sbjct: 1320 TTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQ 1379
Query: 976 LFTFQPPDAKDGLPQKSSVKVN-SALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPP 1034
+ T +P A + P +SS + L+ + PPR + P T PP
Sbjct: 1380 IPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQS---------------PNLTPPP 1424
Query: 1035 SFFAEASSPVSASPVPVGIPTS 1056
+ ++S ++ SP P+ PT+
Sbjct: 1425 THTPHSASDLTVSPDPLLSPTA 1446
Score = 40.8 bits (94), Expect = 0.007
Identities = 61/237 (25%), Positives = 80/237 (33%), Gaps = 44/237 (18%)
Query: 576 TANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRG 635
T Q M T P P + P T PT T+P P P+ +TP P
Sbjct: 1260 TTTPQPFTTMQPTTMPHPTTTPHPTTTPHPT---TTP---HPTTTPHPTMTPDPTTTPYP 1313
Query: 636 VSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKP 695
++P P P P P S P +S+P L T KP
Sbjct: 1314 TTTP--DPTTTPHPTTPDPSSTPVI-----------TTVSLPTSLGTELSSPTLAPTVKP 1360
Query: 696 ------MFTFKEPKVS----PNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNF 745
FT P S P E L++S + T D ED+ +++ N
Sbjct: 1361 SLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNL 1420
Query: 746 MQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAP-TQPPAFP-TSNPSKG 800
TPPP S+S V+P P+ SP P PP P T P+ G
Sbjct: 1421 ---------TPPPT---HTPHSASDLTVSP-DPLLSPTAHPLDHPPLDPLTLGPTPG 1464
Score = 35.0 bits (79), Expect = 0.39
Identities = 56/302 (18%), Positives = 99/302 (32%), Gaps = 33/302 (10%)
Query: 573 TSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADF--PAPPPYSAVTPPPD 630
TS+ + + ++ T++ P S P +P + S + P+P P+ TP P
Sbjct: 1099 TSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPT 1158
Query: 631 AFSRGVS--SPIAGPAQPPPWPQPAPWSQPAFYDSSERI----------ASRDERISVPA 678
++ +P P P P P P S I + +P
Sbjct: 1159 MAPDPITTLNPTVTP-HFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPD 1217
Query: 679 KRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSL 738
T + TT P T P +P+P ++ T + + + ++
Sbjct: 1218 PTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTIT--------HSTMIPDPTTTPQPFTTM 1269
Query: 739 GAEACNFMQSSSAKQKTP-PPVAPKPAV---KSSSSQPVTPVSPVWSPGVAPTQPPAFPT 794
++ TP P P P + + P T P +P PT P T
Sbjct: 1270 QPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPD--PTTTPHPTT 1327
Query: 795 SNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAV 854
+PS V++++ + + P PQ + P P ST + +
Sbjct: 1328 PDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTA----PAPHTSTSQIPTL 1383
Query: 855 QP 856
+P
Sbjct: 1384 EP 1385
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 62.0 bits (149), Expect = 3e-09
Identities = 30/78 (38%), Positives = 51/78 (65%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
Query: 69 VIKLMESITDSLQMLIKR 86
++S + +L + +++
Sbjct: 65 AQNKIKSASYNLSLTLQK 82
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 62.0 bits (149), Expect = 3e-09
Identities = 30/78 (38%), Positives = 51/78 (65%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
Query: 69 VIKLMESITDSLQMLIKR 86
++S + +L + +++
Sbjct: 65 AQNKIKSASYNLSLTLQK 82
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 584 PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADF-PAPPPYSAVTPPPD---AFSRGVSSP 639
P T P P PA ++P SP+ + P+P P +P P+ A S S
Sbjct: 316 PTPYTPSPAPAYTPSPAPAYTP-----SPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG 370
Query: 640 IAGPAQPPPWPQPAPWSQ 657
A PA PPW +SQ
Sbjct: 371 PAEPASRPPWVTDDSFSQ 388
Score = 31.2 bits (69), Expect = 5.6
Identities = 30/123 (24%), Positives = 45/123 (36%), Gaps = 11/123 (8%)
Query: 729 SGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPV----WSPGV 784
S P+ S A + + ++ + P APKP V +++S + PV +SP
Sbjct: 251 SRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP 310
Query: 785 APTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKP 844
P T +P+ S PS P S P P NY P P
Sbjct: 311 GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAP-------NYNPAP 363
Query: 845 TVS 847
+V+
Sbjct: 364 SVA 366
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 61.6 bits (148), Expect = 4e-09
Identities = 146/634 (23%), Positives = 239/634 (37%), Gaps = 77/634 (12%)
Query: 482 EMLPDTTGKGALMFAKRRERMDQI----TAQKEEDKVG--GTPSREQDAAQTDGLRTTTS 535
E D TG+ L K+ Q+ T ++E DK G +P R++++ + + + T+
Sbjct: 841 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVE-IETSEE 899
Query: 536 YQRKEEESVRTQSSVSKSYI-EVSHGLGHVPQQNGFSGTSETANIQRMVPM------NRT 588
Q K+ V+ Q+ SK++ EV + + + A ++ VP +
Sbjct: 900 IQEKQ---VQKQTLPSKAFEREVERPVAN--------RECDPAELEEKVPKVILERDTQR 948
Query: 589 AKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPA-QPP 647
+P GS +Q SPT D P P ++ P + S G SP++ Q
Sbjct: 949 GEPEGGSQDQKGQASSPTPEPGVGAGDLPGP---TSAPVPSGSQSGGRGSPVSPRRHQKG 1005
Query: 648 PWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPN 707
P ++ A + SR ++ S A + EA KP+ + + ++P
Sbjct: 1006 LLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPA-PPQKPLNSQSQKHLAPP 1064
Query: 708 PELLSLLQNSEGK-RGTGAGGDSGPEEDYLSLGAEACN---FMQSSSAKQKTPPPV---A 760
P L LL + + R T G E LS E + +++ + + TP P A
Sbjct: 1065 PLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAA 1124
Query: 761 PKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPAS 820
P+P +S++QPVTP P + T + T P VV + QPS +P +
Sbjct: 1125 PEPHPSTSTAQPVTP-KPTSQATRSRTNRSSVKTPEP----VVPTAPELQPSTSTDQPVT 1179
Query: 821 TLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQ 880
+ + +G + S++ P PT +QP S + P S +Q R+
Sbjct: 1180 SEPTSQVTRGRK----SRSSVKTPETVVPTALELQPST---STDRPVTSEPTSQATRGRK 1232
Query: 881 SRM-----EKYVVDSDTVQAHAARAQ----SPTPSLPASWKYSSNVRAPPPVA-----YN 926
+R E V + +Q + Q PT K S+V+ P PV
Sbjct: 1233 NRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELR 1292
Query: 927 PIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKD 986
P S P+ + + + M K + V+ P +L S T QP
Sbjct: 1293 PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPE-----TVVPTAP-ELQISTSTDQPV---- 1342
Query: 987 GLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSA 1046
P+ +S S M P +P + S+ P P S S+
Sbjct: 1343 -TPKPTSRTTRSRTNMSSVKNPESTVPIAP-ELPPSTSTEQPVTPEPTSRATRGRKNRSS 1400
Query: 1047 SPVP-VGIPTSPKQE-SASSSYFVAPRPKFSAKK 1078
P +PT+PK E S S+ V P P A +
Sbjct: 1401 GKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATR 1434
Score = 45.1 bits (105), Expect = 4e-04
Identities = 116/595 (19%), Positives = 200/595 (33%), Gaps = 82/595 (13%)
Query: 518 PSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETA 577
PS D T + + RK SV+T +V + +E+ TSE
Sbjct: 1170 PSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTS-----TDRPVTSEPT 1224
Query: 578 NIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVS 637
+ NR++ P V A P+ + P+ + P Y A + S
Sbjct: 1225 SQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVT---SEPTYQATRGRKNRSSVKTP 1281
Query: 638 SPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRR---STTK 694
P+ P P P + +S SR SV T + + + ST +
Sbjct: 1282 EPVV-PTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQ 1340
Query: 695 PMFTFKEPKVSPNPELLSLLQNSEGKRGTG-----AGGDSGPEEDYLSLGAEACNFMQSS 749
P+ + + + +S ++N E + P + A +SS
Sbjct: 1341 PVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSS 1400
Query: 750 SAKQKTPPPVAPKPAVKSSSSQPVT------------------------PVSPVWSPGVA 785
+T P APK +S+ QPVT P +P P +
Sbjct: 1401 GKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTS 1460
Query: 786 PTQP-PAFPTSNPSKG-TVVSSIKIAQ---PSYPPARPASTLN---VAGPFKGPQAAVAS 837
QP PTS ++G T SS+K + P+ P + +++ + + P +
Sbjct: 1461 TDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKN 1520
Query: 838 QNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQS--RMEKYVVDSDTVQA 895
++ P P +QP P + R + R S E V + +Q
Sbjct: 1521 RSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQP 1580
Query: 896 HAARAQ----SPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMG 951
+R Q PT S+V+ P PV P+ P + K+
Sbjct: 1581 STSRNQLVTPEPTSRATRCRTNRSSVKTPEPVV------PTAPEPHPTTSTDQPVTPKLT 1634
Query: 952 KKKGKKPLNALDVMKHQPYQLNAS-LFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRP 1010
+ ++ N V +P + AS L F P D + P
Sbjct: 1635 SRATRRKTNRSSVKTPKPVEPAASDLEPFTPTD-------------------QSVTPEAI 1675
Query: 1011 VNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSS 1065
+++S+V ++P T+ P F + ++ SP P+ P+ K++ A+ +
Sbjct: 1676 AQGGQSKTLRSSTVRAMPVPTT-PEFQSPVTTDQPISPEPITQPSCIKRQRAAGN 1729
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 60.8 bits (146), Expect = 7e-09
Identities = 32/92 (34%), Positives = 57/92 (61%), Gaps = 2/92 (2%)
Query: 2 GTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKAS-GSGLCEGDEVVSINGNP 60
G+ ++ + + GGAPWGF L+GG E +PL V+KI + KA+ + GDE+V+ING P
Sbjct: 6 GSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTP 65
Query: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGIS 92
+ E + L++ L+++++R ++ +S
Sbjct: 66 LYG-SRQEALILIKGSFRILKLIVRRRNAPVS 96
>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
Length = 246
Score = 60.5 bits (145), Expect = 9e-09
Identities = 27/79 (34%), Positives = 47/79 (59%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++ G +PWGFRL GG++ PL ++++ SKA+ + LC GD + +ING +T+ E
Sbjct: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
Query: 69 VIKLMESITDSLQMLIKRP 87
++ D L + + RP
Sbjct: 65 AQNRIKGCHDHLTLSVSRP 83
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 60.5 bits (145), Expect = 9e-09
Identities = 27/79 (34%), Positives = 47/79 (59%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++ G +PWGFRL GG++ PL ++++ SKA+ + LC GD + +ING +T+ E
Sbjct: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
Query: 69 VIKLMESITDSLQMLIKRP 87
++ D L + + RP
Sbjct: 65 AQNRIKGCHDHLTLSVSRP 83
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 60.5 bits (145), Expect = 9e-09
Identities = 89/343 (25%), Positives = 120/343 (34%), Gaps = 38/343 (11%)
Query: 746 MQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAF------PTSNPSK 799
+Q+ Q TPP PA+ SS P+ SP P +P+ PP+ P + PS+
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP--SPSAPPSLQTLPSPPATPPSQ 325
Query: 800 GTVV--SSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPG 857
T S A S+ P+ P S L P P A+ P P S P P
Sbjct: 326 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385
Query: 858 AVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNV 917
P+ A + S VQA SP S P S +
Sbjct: 386 PQAPN------------ALAVHLLQAPFSPPPSPPVQAPF----SPPASPPVSPSATPPS 429
Query: 918 RAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLF 977
+APP +A P+ P P A+ PSA P + PL + P Q +L
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ----LAKPPPQAPPALA 485
Query: 978 TFQPPDAKDGLPQ-KSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSF 1036
T PP LP +S + + +LP P+ P QA V + P PPS
Sbjct: 486 T--PP--LQALPSPPASFPGQAPFSPSASLPMSPLATPPP---QAPPVLAAPLLQVPPSP 538
Query: 1037 FAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKS 1079
A + P G TS + + P P S S
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 581
Score = 57.0 bits (136), Expect = 1e-07
Identities = 110/493 (22%), Positives = 166/493 (33%), Gaps = 48/493 (9%)
Query: 486 DTTGKGALMFAKRRERMDQITAQKEEDKVGGTPS----REQDAAQTD-GLRTTTSYQRKE 540
+T +G A +R + + GTPS R AA T+ GL R
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 541 EESVRTQSSVSK----SYIEVSHGLGHVPQQNGFSGTSETANIQRMV-PMNRTAKPFPGS 595
+ + SVS S E S P G + ++ P++ A+ P +
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 596 VNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPW 655
P P P++ P P A+ PP R ++P GP P P+P
Sbjct: 251 RGTPRAPAHPSQ---------PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 656 SQPAFYDSSERIASRDERISVPAKRTGILQEAKRRST-----TKPMFTFKEPKVSPNPEL 710
+ P+ + P++ T L ++T + P+ P P L
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361
Query: 711 LSLLQNSEGKRGTGAGGDSGP--EEDYLSLGAEACNFMQSSSAKQKTPPPVAP-----KP 763
L + A P + A A + +Q+ + +PP AP P
Sbjct: 362 --ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 764 AVKSSSSQP-VTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTL 822
V S++ P P S P P PPA P +PS P PP A L
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS--------ATPPPQAPPPLAAPPL 471
Query: 823 NVA--GPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQ 880
+A P P A P P S P P A P + L + + A
Sbjct: 472 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 531
Query: 881 SRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRA---PPPVAYNPIHSPSYPLAA 937
++ S T+QA R +P P S + A PPP + +P + S P A
Sbjct: 532 LQVPPSPPASPTLQA-PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 590
Query: 938 LKSQPSAAQPSKM 950
S + + P ++
Sbjct: 591 GHSSSATSTPEEL 603
Score = 52.8 bits (125), Expect = 2e-06
Identities = 95/395 (24%), Positives = 133/395 (33%), Gaps = 59/395 (14%)
Query: 599 PATPFSP-TRNMTSPIAD-----FPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQP 652
PATP S T ++ SP P+PP TPPP A P+ P PP P
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378
Query: 653 APWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLS 712
+P + P+ + A +LQ + P+ P SP P S
Sbjct: 379 SPLATPSPQAPN-------------ALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPS 424
Query: 713 LLQNSEGKRGTGAG----GDSGPEEDYLSLGA----EACNFMQSSSAKQKTPPPVAPKPA 764
S+ A S P +S A +A + + + PPP AP PA
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PA 483
Query: 765 VKSSSSQPVTPVSPVWSPGVAPTQPPA------FPTSNPSKGTVVSSIKIAQPSYPPARP 818
+ + Q + P P PG AP P A T P V+++ + P PPA P
Sbjct: 484 LATPPLQAL-PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 542
Query: 819 ASTLNVAGPFKGPQAAVASQNYT--------------PKPTVSTPTVNAVQPGAVGPSNE 864
P GP +V+ T P T+S P + A E
Sbjct: 543 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 602
Query: 865 LPGM-SGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPV 923
L G SG A D++ H A A S P+ P +++ + P P
Sbjct: 603 LRGYDSGPEGGAAASPPP-------DAELAACHPA-AWSRGPAPPLAFRGAPGAPLPWPP 654
Query: 924 AYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKP 958
A P + P +A P+ G P
Sbjct: 655 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 38.1 bits (87), Expect = 0.046
Identities = 78/347 (22%), Positives = 122/347 (35%), Gaps = 56/347 (16%)
Query: 754 KTPPPVAPKPAVKSSSSQPVTPVS--PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQP 811
+ P + P+P PVTP + + + G +P A T+ S A P
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP 79
Query: 812 SYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP--TVNAVQPGAVGPSN---ELP 866
+ PAS P ++N +P P VS+P +PG +G
Sbjct: 80 TRTSRPPASGRGERAP--------PAKNTSPGP-VSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 867 GMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQS-PTPSLPA------SWKYSSNVRA 919
RG A ++S + A A R S PTP P+ S + V
Sbjct: 131 ETVARGKATEAPKRSALS----------AGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 180
Query: 920 PPPVAYN----PIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNAS 975
P P P P +++ S+ S +PS +++ P + + L++S
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSA-SEHSTTEPSPAARRR---PSAGGGLQRPASRSLSSS 236
Query: 976 LFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPS 1035
P A+ G + + + A P +P P +QA P T P
Sbjct: 237 ATPLSSP-ARSGPSARGTPRA-------PAHPSQP----KPKGLQA---LRPPQVTPPRK 281
Query: 1036 FFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVT 1082
A A P+S+SP+ P++P SA S P P + T
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT 328
Score = 37.4 bits (85), Expect = 0.078
Identities = 79/337 (23%), Positives = 116/337 (34%), Gaps = 71/337 (21%)
Query: 574 SETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAP---PPYSAVTPPPD 630
S +A P + A P + PA+P P +P P P PP PPP
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 631 AFSRGVSSPI-AGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISV------------P 677
A + P+ A P+ P +P AP+S A S + V P
Sbjct: 480 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539
Query: 678 AKRTGILQEAKRRSTTKPMFTFKEPKVS-------PNPELLSLLQNSEGK--RGTGAGGD 728
A T LQ +R T P + P+++ P P S G G +
Sbjct: 540 ASPT--LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597
Query: 729 SGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQ 788
S PEE ++ + + +P P + ++ P WS G AP
Sbjct: 598 STPEE------------LRGYDSGPEGGAAASPPPDAELAACHPA-----AWSRGPAP-- 638
Query: 789 PPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVST 848
P AF P P P +T GP G + + T P +T
Sbjct: 639 PLAFR---------------GAPGAPLPWPPAT----GP--GSADGLCTIYETEGPESAT 677
Query: 849 PTVNAVQPG-AVGPS-NELPGMSGRGAQLFAKRQSRM 883
P A+ PG + G S + +G GA + +Q+R+
Sbjct: 678 PAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 714
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 60.1 bits (144), Expect = 1e-08
Identities = 128/601 (21%), Positives = 212/601 (35%), Gaps = 109/601 (18%)
Query: 520 REQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANI 579
R DA +G T +RK +SV +SKS + S L Q + F G S + N
Sbjct: 2055 RASDAKNQEGKVNT---RRKSTDSV----PISKSTLSRSLSL----QASDFDGASSSGNP 2103
Query: 580 QRMV---------------PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSA 624
+ + + RT KP P S+ + T PT T P+ + P +
Sbjct: 2104 EAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTE--TPPVKETQQEPDEES 2161
Query: 625 VTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGIL 684
+ P + + + A P P +PA V K L
Sbjct: 2162 LVPSGENLASETKTESAKTEGPSPALLEETPLEPA----------------VGPKAACPL 2205
Query: 685 QEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEA-- 742
P + SP +L + + G DSG +ED + G
Sbjct: 2206 DSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRL 2265
Query: 743 -CNFMQSSSA---KQKTPPP---VAPKPAVKSSSSQPVTPVSP--VWSPGVAPTQPPAFP 793
++ + S+ +Q+ PPP + KP K +P +P + + +P + PA P
Sbjct: 2266 EFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP 2325
Query: 794 TSNP-SKGTVVSSI-KIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTP--------- 842
P +KGT I K P++ P S + + P+ S N+ P
Sbjct: 2326 NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ-----ESPKLPQQSYNFDPDTCDESVDP 2380
Query: 843 -KPTVSTPTVNAVQPGAV---GPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAA 898
K + TP+ + P + + E G+ G G AK+ +K + +DT + +
Sbjct: 2381 FKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKK----KKTPLKTDTFRVKKS 2436
Query: 899 RAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQ-------------PSAA 945
+SP P+ + PPV +H+ A+ +Q
Sbjct: 2437 PKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYP 2496
Query: 946 QPSKM----GKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALA 1001
QPS + + K P LD + + + P D D P+K ++ + +
Sbjct: 2497 QPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPKKQALYLMFDTS 2554
Query: 1002 MKQALPPRPVN-AASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE 1060
+ + PV + SPT SS A + ++ + PVP G+ +P QE
Sbjct: 2555 QESPVKSSPVRMSESPTPCSGSSFEETEALVN--------TAAKNQHPVPRGL--APNQE 2604
Query: 1061 S 1061
S
Sbjct: 2605 S 2605
Score = 42.7 bits (99), Expect = 0.002
Identities = 116/532 (21%), Positives = 170/532 (31%), Gaps = 97/532 (18%)
Query: 606 TRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQP---------PPWP------ 650
T T+P+ PAPPP PPP+ S P +P P P
Sbjct: 1955 TPESTTPVKAPPAPPP-----PPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVE 2009
Query: 651 ----QPAPWSQPAFYDSSERIASRD------ERISVPAKRTGILQEAKRRSTTKPMFTFK 700
+P S A +D + IAS + I + + A + +
Sbjct: 2010 GSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTR 2069
Query: 701 EPKVSPNPELLSLLQNSEGKRGT---GAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPP 757
P S L S + + GA PE L+ A + +SS ++T
Sbjct: 2070 RKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKK 2129
Query: 758 PVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPT-SNPSKGTVVSSIKIAQPS---- 812
P P K ++ +P T PV P + P+ N + T S K PS
Sbjct: 2130 PRPPSLKKKQTTKKP-TETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALL 2188
Query: 813 -YPPARPASTLNVAGPFKGPQA---------AVASQNYTPKPTVSTPTVNAVQPGAVGPS 862
P PA A P A QN P + P A + G V PS
Sbjct: 2189 EETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPS 2248
Query: 863 NELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPP 922
+ SG AK S ++ D + + ++P P+ K P
Sbjct: 2249 D-----SGGQEDSPAKGLSVRLEFDYSEDK-SSWDNQQENPPPTKKIGKK---------P 2293
Query: 923 VAYNPIHSPSYPLAALK------SQP-SAAQPSKMGKKKGK-------------KPLNAL 962
VA P+ P K S P S A+P+ + KG P ++
Sbjct: 2294 VAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSST 2353
Query: 963 DVMKHQPYQLNASLFTFQPPDAKDGL-PQKSSVKVNSALAMKQALPPRPVNAASPTNVQA 1021
M+ P +L + F P + + P K+S K S+ + A P +A V
Sbjct: 2354 SKMQESP-KLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDG 2412
Query: 1022 SSVYSVPAYTSPP----SFFAE-------ASSPVSASPVPVGIPTSPKQESA 1062
+ P +F + S P S P P P +P SA
Sbjct: 2413 DGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISA 2464
Score = 34.7 bits (78), Expect = 0.51
Identities = 85/368 (23%), Positives = 126/368 (34%), Gaps = 69/368 (18%)
Query: 617 PAPPPYS-----------AVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQ-------P 658
P+PPP A PP + ++P GP P +PAP + P
Sbjct: 96 PSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFP 155
Query: 659 AFYDSSERIASRDERISVPA--KRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQN 716
A DSS E +VP+ + +E ++ S + + P +SP P L ++
Sbjct: 156 AERDSS---TPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVP-LREPMKA 211
Query: 717 SEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPV 776
G GG E++ G Q ++ Q TP AP A + + S V
Sbjct: 212 PLCGEGDQPGGFESQEKEAAG-GFPPAESRQGVASVQVTPE--APAAAQQGTESSAVLEK 268
Query: 777 SPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVA 836
SP+ P Q PA S+ +G Q PP L P+ +
Sbjct: 269 SPL-KPMAPIPQDPAPRASDRERG---------QGEAPPQYLTDDLEFLRACHLPR---S 315
Query: 837 SQNYTPKPTVSTPTVNAVQP--GAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ 894
+ P+ V+ + + Q GA P ELP G + K +D+ VQ
Sbjct: 316 NSGAAPEAEVNAASQESCQQPVGAYLPHAELPW--GLPSPALVPEAGGSGKEALDTIDVQ 373
Query: 895 AH---------------AARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALK 939
H A P LP S P P P ++P ++L
Sbjct: 374 GHPQTGMRGTKPNQVVCVAAGGQPEGGLPVS---------PEPSLLTPTEE-AHPASSLA 423
Query: 940 SQPSAAQP 947
S P+A P
Sbjct: 424 SFPAAQIP 431
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 60.1 bits (144), Expect = 1e-08
Identities = 128/601 (21%), Positives = 212/601 (35%), Gaps = 109/601 (18%)
Query: 520 REQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANI 579
R DA +G T +RK +SV +SKS + S L Q + F G S + N
Sbjct: 201 RASDAKNQEGKVNT---RRKSTDSV----PISKSTLSRSLSL----QASDFDGASSSGNP 249
Query: 580 QRMV---------------PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSA 624
+ + + RT KP P S+ + T PT T P+ + P +
Sbjct: 250 EAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTE--TPPVKETQQEPDEES 307
Query: 625 VTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGIL 684
+ P + + + A P P +PA V K L
Sbjct: 308 LVPSGENLASETKTESAKTEGPSPALLEETPLEPA----------------VGPKAACPL 351
Query: 685 QEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEA-- 742
P + SP +L + + G DSG +ED + G
Sbjct: 352 DSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRL 411
Query: 743 -CNFMQSSSA---KQKTPPP---VAPKPAVKSSSSQPVTPVSP--VWSPGVAPTQPPAFP 793
++ + S+ +Q+ PPP + KP K +P +P + + +P + PA P
Sbjct: 412 EFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP 471
Query: 794 TSNP-SKGTVVSSI-KIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTP--------- 842
P +KGT I K P++ P S + + P+ S N+ P
Sbjct: 472 NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ-----ESPKLPQQSYNFDPDTCDESVDP 526
Query: 843 -KPTVSTPTVNAVQPGAV---GPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAA 898
K + TP+ + P + + E G+ G G AK+ +K + +DT + +
Sbjct: 527 FKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKK----KKTPLKTDTFRVKKS 582
Query: 899 RAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQ-------------PSAA 945
+SP P+ + PPV +H+ A+ +Q
Sbjct: 583 PKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYP 642
Query: 946 QPSKM----GKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALA 1001
QPS + + K P LD + + + P D D P+K ++ + +
Sbjct: 643 QPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPKKQALYLMFDTS 700
Query: 1002 MKQALPPRPVN-AASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE 1060
+ + PV + SPT SS A + ++ + PVP G+ +P QE
Sbjct: 701 QESPVKSSPVRMSESPTPCSGSSFEETEALVN--------TAAKNQHPVPRGL--APNQE 750
Query: 1061 S 1061
S
Sbjct: 751 S 751
Score = 42.7 bits (99), Expect = 0.002
Identities = 116/532 (21%), Positives = 170/532 (31%), Gaps = 97/532 (18%)
Query: 606 TRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQP---------PPWP------ 650
T T+P+ PAPPP PPP+ S P +P P P
Sbjct: 101 TPESTTPVKAPPAPPP-----PPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVE 155
Query: 651 ----QPAPWSQPAFYDSSERIASRD------ERISVPAKRTGILQEAKRRSTTKPMFTFK 700
+P S A +D + IAS + I + + A + +
Sbjct: 156 GSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTR 215
Query: 701 EPKVSPNPELLSLLQNSEGKRGT---GAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPP 757
P S L S + + GA PE L+ A + +SS ++T
Sbjct: 216 RKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKK 275
Query: 758 PVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPT-SNPSKGTVVSSIKIAQPS---- 812
P P K ++ +P T PV P + P+ N + T S K PS
Sbjct: 276 PRPPSLKKKQTTKKP-TETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALL 334
Query: 813 -YPPARPASTLNVAGPFKGPQA---------AVASQNYTPKPTVSTPTVNAVQPGAVGPS 862
P PA A P A QN P + P A + G V PS
Sbjct: 335 EETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPS 394
Query: 863 NELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPP 922
+ SG AK S ++ D + + ++P P+ K P
Sbjct: 395 D-----SGGQEDSPAKGLSVRLEFDYSEDK-SSWDNQQENPPPTKKIGKK---------P 439
Query: 923 VAYNPIHSPSYPLAALK------SQP-SAAQPSKMGKKKGK-------------KPLNAL 962
VA P+ P K S P S A+P+ + KG P ++
Sbjct: 440 VAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSST 499
Query: 963 DVMKHQPYQLNASLFTFQPPDAKDGL-PQKSSVKVNSALAMKQALPPRPVNAASPTNVQA 1021
M+ P +L + F P + + P K+S K S+ + A P +A V
Sbjct: 500 SKMQESP-KLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDG 558
Query: 1022 SSVYSVPAYTSPP----SFFAE-------ASSPVSASPVPVGIPTSPKQESA 1062
+ P +F + S P S P P P +P SA
Sbjct: 559 DGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISA 610
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,375,708
Number of Sequences: 37866
Number of extensions: 2929645
Number of successful extensions: 23255
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 1109
Number of HSP's that attempted gapping in prelim test: 14559
Number of HSP's gapped (non-prelim): 6766
length of query: 1093
length of database: 18,247,518
effective HSP length: 113
effective length of query: 980
effective length of database: 13,968,660
effective search space: 13689286800
effective search space used: 13689286800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.