Guide to the Human Genome
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Name: MDC1 Sequence: fasta or formatted (2089aa) NCBI GI: 132626688
Description:

mediator of DNA-damage checkpoint 1

Referenced in:

DNases, Recombination, and DNA Repair

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9        144           3
 C cysteine            1.0         20           2
 D aspartate           4.9        102           3
 E glutamate           9.8        204           5
 F phenylalanine       1.5         32           2
 G glycine             5.4        112           2
 H histidine           1.6         34           1
 I isoleucine          2.7         56           2
 K lysine              4.9        103           2
 L leucine             6.5        136           3
 M methionine          0.9         19           1
 N asparagine          1.8         37           1
 P proline            11.8        247           4
 Q glutamine           6.0        125           2
 R arginine            7.1        148           2
 S serine              9.6        201           3
 T threonine           9.5        198           3
 V valine              7.4        154           2
 W tryptophan          0.4          8           1
 Y tyrosine            0.4          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mediator of DNA-damage checkpoint 1 
PRG4                  0.044   proteoglycan 4 isoform D 
PRG4                  0.044   proteoglycan 4 isoform C 
PRG4                  0.044   proteoglycan 4 isoform B 
PRG4                  0.044   proteoglycan 4 isoform A 
MUC2                  0.035   mucin 2 precursor 
NACA                  0.032   nascent polypeptide-associated complex alpha subuni...
MUC17                 0.029   mucin 17 
MUC6                  0.028   mucin 6, gastric 
LOC100294420          0.028   PREDICTED: similar to mucin 2 
ZAN                   0.024   zonadhesin isoform 3 
ZAN                   0.024   zonadhesin isoform 6 
SRRM2                 0.023   splicing coactivator subunit SRm300 
MUC3A                 0.023   PREDICTED: mucin 3A, intestinal 
LOC284297             0.022   hypothetical protein LOC284297 
LOC100294236          0.022   PREDICTED: similar to diffuse panbronchiolitis crit...
MUC5B                 0.021   mucin 5, subtype B, tracheobronchial 
MUC3A                 0.021   PREDICTED: mucin 3A, cell surface associated, parti...
FLJ22184              0.021   PREDICTED: hypothetical protein FLJ22184 
PAXIP1                0.020   PAX interacting protein 1 
DPCR1                 0.020   diffuse panbronchiolitis critical region 1 protein ...
MUC12                 0.019   PREDICTED: mucin 12 
SRRM1                 0.019   serine/arginine repetitive matrix 1 
MUC16                 0.019   mucin 16 
LOC100133756          0.018   PREDICTED: hypothetical protein, partial 
POLR2A                0.018   DNA-directed RNA polymerase II A 
MUC4                  0.018   mucin 4 isoform a 
NEFH                  0.018   neurofilament, heavy polypeptide 200kDa 
NACAD                 0.018   NAC alpha domain containing 
NACAD                 0.018   PREDICTED: NAC alpha domain containing 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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