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Search of human proteins with 193083183
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
(1261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 2529 0.0
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 2162 0.0
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 2162 0.0
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 340 4e-93
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 337 4e-92
gi|40353727 synaptopodin isoform A [Homo sapiens] 119 1e-26
gi|158303333 synaptopodin isoform B [Homo sapiens] 100 9e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni... 78 5e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 7e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 71 6e-12
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 71 6e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 70 2e-11
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 69 3e-11
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 69 4e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 69 4e-11
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 65 3e-10
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 65 3e-10
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 65 5e-10
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 65 5e-10
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 65 5e-10
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 65 5e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 7e-10
gi|91982772 mucin 17 [Homo sapiens] 64 7e-10
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 64 1e-09
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 62 3e-09
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 62 3e-09
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 61 6e-09
gi|112421108 capicua homolog [Homo sapiens] 61 6e-09
gi|118600967 shroom family member 4 [Homo sapiens] 61 8e-09
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 61 8e-09
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 2529 bits (6555), Expect = 0.0
Identities = 1261/1261 (100%), Positives = 1261/1261 (100%)
Query: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP
Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
Query: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
Query: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE
Sbjct: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
Query: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH
Sbjct: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
Query: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR
Sbjct: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
Query: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR
Sbjct: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
Query: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE
Sbjct: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
Query: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK
Sbjct: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
Query: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE
Sbjct: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
Query: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA
Sbjct: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
Query: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF
Sbjct: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
Query: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK
Sbjct: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
Query: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW
Sbjct: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
Query: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY
Sbjct: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
Query: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA
Sbjct: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
Query: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN
Sbjct: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
Query: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ
Sbjct: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
Query: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG
Sbjct: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
Query: 1081 VTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPL 1140
VTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPL
Sbjct: 1081 VTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPL 1140
Query: 1141 GLVDDAFQPRNIQESIVANVVSAARRKVLPGPPEDWNERLSYIPQTQKAYMGSCGRQEYN 1200
GLVDDAFQPRNIQESIVANVVSAARRKVLPGPPEDWNERLSYIPQTQKAYMGSCGRQEYN
Sbjct: 1141 GLVDDAFQPRNIQESIVANVVSAARRKVLPGPPEDWNERLSYIPQTQKAYMGSCGRQEYN 1200
Query: 1201 VTANNNMSTTSQYGSQLPYAYYRQASRNDSAIMSMETRSDYCLPVADYNYNPHPRGWRRQ 1260
VTANNNMSTTSQYGSQLPYAYYRQASRNDSAIMSMETRSDYCLPVADYNYNPHPRGWRRQ
Sbjct: 1201 VTANNNMSTTSQYGSQLPYAYYRQASRNDSAIMSMETRSDYCLPVADYNYNPHPRGWRRQ 1260
Query: 1261 T 1261
T
Sbjct: 1261 T 1261
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 2162 bits (5602), Expect = 0.0
Identities = 1085/1089 (99%), Positives = 1086/1089 (99%)
Query: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP
Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
Query: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
Query: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE
Sbjct: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
Query: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH
Sbjct: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
Query: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR
Sbjct: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
Query: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR
Sbjct: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
Query: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE
Sbjct: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
Query: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK
Sbjct: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
Query: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE
Sbjct: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
Query: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA
Sbjct: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
Query: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF
Sbjct: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
Query: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK
Sbjct: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
Query: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW
Sbjct: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
Query: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY
Sbjct: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
Query: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA
Sbjct: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
Query: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN
Sbjct: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
Query: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ
Sbjct: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
Query: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG
Sbjct: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
Query: 1081 VTIQESGRS 1089
VTIQ +S
Sbjct: 1081 VTIQVKCKS 1089
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 2162 bits (5601), Expect = 0.0
Identities = 1084/1084 (100%), Positives = 1084/1084 (100%)
Query: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP
Sbjct: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
Query: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQI 120
Query: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE
Sbjct: 121 RPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAE 180
Query: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH
Sbjct: 181 ELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVH 240
Query: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR
Sbjct: 241 INSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCR 300
Query: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR
Sbjct: 301 LQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRR 360
Query: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE
Sbjct: 361 SESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELERE 420
Query: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK
Sbjct: 421 ADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDK 480
Query: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE
Sbjct: 481 MEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKE 540
Query: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA
Sbjct: 541 EESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPA 600
Query: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF
Sbjct: 601 TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF 660
Query: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK
Sbjct: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
Query: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW
Sbjct: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW 780
Query: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY
Sbjct: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
Query: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA
Sbjct: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
Query: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN
Sbjct: 901 QSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLN 960
Query: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ
Sbjct: 961 ALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQ 1020
Query: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG
Sbjct: 1021 ASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSG 1080
Query: 1081 VTIQ 1084
VTIQ
Sbjct: 1081 VTIQ 1084
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 340 bits (873), Expect = 4e-93
Identities = 287/825 (34%), Positives = 385/825 (46%), Gaps = 189/825 (22%)
Query: 343 KDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRR 402
+D + + +A+ A+L+R+ESL EK +KEAK+KC++IA LLT APNP+SKGVLMFKKRR+
Sbjct: 244 EDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQ 303
Query: 403 RARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNF 462
RA+KYTLVS+G EEE+G SESE+DEE SD T
Sbjct: 304 RAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFSDARSLTN--QS 350
Query: 463 DWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMDQITAQKEEDKV 514
DWDS +D+E + + G + L + +G+G +F ++R+R D T +
Sbjct: 351 DWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL----- 405
Query: 515 GGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSG 572
+R + AA +GL++ Q E+ S + + P Q G
Sbjct: 406 ----ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-----PFQPGGGA 456
Query: 573 TSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPIADFPAPPPY-S 623
+ +I NR+A+PF PG Q T P +P R S PAPPP+ S
Sbjct: 457 PTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511
Query: 624 AVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ-----------PAPW 655
+ P P +F+ GV S P++G P P P PAP
Sbjct: 512 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 571
Query: 656 SQPAFYDSS------------------------ERIASRDERISVPAKRTGILQEAKRRS 691
S A ++ E ++R++RISVPA RTGILQEA+RR
Sbjct: 572 SAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRG 631
Query: 692 TTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSS 749
T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSLGAEACNFMQ
Sbjct: 632 TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSLGAEACNFMQPV 690
Query: 750 SAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800
A+ KTPPP+APK + P+TP +P P VAP
Sbjct: 691 GARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK------------- 728
Query: 801 TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVG 860
PP+R G G AS P+P
Sbjct: 729 -------------PPSR--------GLLDGLVNGAASSAGIPEP---------------- 751
Query: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSLPASWKYSSNVR 918
P + GRG +LFAKRQSR ++YVV+ R+ SPTPSLP SWKYS N+R
Sbjct: 752 -----PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIR 806
Query: 919 APPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFT 978
APPP+AYNP+ SP +P AA + +Q + K+G + ALD M+HQPYQL ++F
Sbjct: 807 APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRHQPYQLKTAMFC 863
Query: 979 FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFA 1038
F G S K +++ P P A P + + P
Sbjct: 864 FDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTE 923
Query: 1039 EASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGV 1081
AS+PV P P P +P+ S SS F RP+FSA ++G+
Sbjct: 924 LASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGL 965
Score = 84.3 bits (207), Expect = 7e-16
Identities = 36/86 (41%), Positives = 63/86 (73%)
Query: 1 MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNP 60
MG + + ++++GGAPWGFRL GG EQ++PLQV+KIR +S+A +GL E D++++ING
Sbjct: 1 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVS 60
Query: 61 CADLTYPEVIKLMESITDSLQMLIKR 86
C +L++ + L+++ + L + ++R
Sbjct: 61 CTNLSHASAMSLIDASGNQLVLTVQR 86
Score = 47.8 bits (112), Expect = 7e-05
Identities = 121/552 (21%), Positives = 190/552 (34%), Gaps = 88/552 (15%)
Query: 758 PVAPKPAVKSSSSQPVTPVS-PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA 816
P P P + SQ + VS P W G A PPA P + P
Sbjct: 181 PAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLP---------------HGPL 225
Query: 817 RPASTL-NVAGPFKGPQAAVASQNYTPK-PTVSTPTVNAVQPGAVGPS-----------N 863
RP L + GP P A + YT K ++Q ++ +
Sbjct: 226 RPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLT 285
Query: 864 ELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQS----PTPSLPASWKYSSNVRA 919
P +G +F KR+ R +KY + S A + PT + S+ R+
Sbjct: 286 AAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARS 345
Query: 920 PPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNAS---L 976
+ LA S+ S Q S +G + + + + + Q + ++S L
Sbjct: 346 LTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL 405
Query: 977 FTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNA--ASPTNVQASSVYSVPAYTSPP 1034
+P +G +S + SA LPP P+ A ASP Q PA P
Sbjct: 406 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA----P 461
Query: 1035 SFFAEASSPVSAS-----PVPVGI---PTSPKQESAS------------SSYFVAPRPKF 1074
S F ++ P + P + P +PK+ + S SS P P F
Sbjct: 462 SIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSF 521
Query: 1075 SAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEA 1134
+ SGV RS P +TS +Y P S P A + P P A
Sbjct: 522 T---SGVPSHAPVSGSPSTPRSSGPVTATSS-LYIPAPSRPVTPGG----APEPPAPPSA 573
Query: 1135 AAKSPLGLVDDAFQPRNIQESIVANVVSAARRKVLPGPPEDWNERLSYIPQTQ------- 1187
AA + + F ++ S A + A P PP +R+S +P +
Sbjct: 574 AAMTSTASI---FLSAPLRPS--ARPEAPAPGPGAPEPPSAREQRIS-VPAARTGILQEA 627
Query: 1188 -----KAYMGSCGRQEYNVTANNNMSTTSQYGSQLPYAYYRQASRNDSAIMSMETRSDYC 1242
+ M G++E + N + + Q + P A ++ + A+ ++
Sbjct: 628 RRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM 687
Query: 1243 LPVADYNYNPHP 1254
PV +Y P
Sbjct: 688 QPVGARSYKTLP 699
>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
Length = 753
Score = 337 bits (864), Expect = 4e-92
Identities = 288/836 (34%), Positives = 387/836 (46%), Gaps = 194/836 (23%)
Query: 337 EDPRSEKDHSR-----PHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNS 391
++P S+ + + P + +A L+R+ESL EK +KEAK+KC++IA LLT APNP+S
Sbjct: 9 QEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHS 68
Query: 392 KGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLS 451
KGVLMFKKRR+RA+KYTLVS+G EEE+G SESE+DEE S
Sbjct: 69 KGVLMFKKRRQRAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFS 117
Query: 452 DVDDNTQVVNFDWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMD 503
D T DWDS +D+E + + G + L + +G+G +F ++R+R D
Sbjct: 118 DARSLTN--QSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRAD 175
Query: 504 QITAQKEEDKVGGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGL 561
T + +R + AA +GL++ Q E+ S + +
Sbjct: 176 SSTQEL---------ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-- 224
Query: 562 GHVPQQNGFSGTSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPI 613
P Q G + +I NR+A+PF PG Q T P +P R S
Sbjct: 225 ---PFQPGGGAPTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG 276
Query: 614 ADFPAPPPY-SAVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ---- 651
PAPPP+ S+ P P +F+ GV S P++G P P P
Sbjct: 277 GLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVT 336
Query: 652 -------PAPWSQPAFYDSS------------------------ERIASRDERISVPAKR 680
PAP S A ++ E ++R++RISVPA R
Sbjct: 337 PGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 396
Query: 681 TGILQEAKRRSTTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSL 738
TGILQEA+RR T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSL
Sbjct: 397 TGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSL 455
Query: 739 GAEACNFMQSSSAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789
GAEACNFMQ A+ KTPPP+APK + P+TP +P P VAP
Sbjct: 456 GAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK-- 504
Query: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
PP+R G G AS P+P
Sbjct: 505 ------------------------PPSR--------GLLDGLVNGAASSAGIPEP----- 527
Query: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSL 907
P + GRG +LFAKRQSR ++YVV+ R+ SPTPSL
Sbjct: 528 ----------------PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSL 571
Query: 908 PASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKH 967
P SWKYS N+RAPPP+AYNP+ SP +P AA + +Q + K+G + ALD M+H
Sbjct: 572 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRH 628
Query: 968 QPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSV 1027
QPYQL ++F F G S K +++ P P A P + +
Sbjct: 629 QPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA 688
Query: 1028 PAYTSPPSFFAEASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGV 1081
P AS+PV P P P +P+ S SS F RP+FSA ++G+
Sbjct: 689 TTLDEPIWRTELASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGL 741
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 119 bits (299), Expect = 1e-26
Identities = 109/329 (33%), Positives = 147/329 (44%), Gaps = 51/329 (15%)
Query: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAP 920
P+ L SG+GA+L+A+RQSRMEKYV++S + AR SPT SLP+SWKY +N
Sbjct: 469 PNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNA--- 525
Query: 921 PPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNAL---DVMKHQPYQLNASLF 977
P A+ P+ P+ + G P N + + K PYQL SLF
Sbjct: 526 -PGAFR----------VASRSPARTPPASL--YHGYLPENGVLRPEPTKQPPYQLRPSLF 572
Query: 978 TFQP-PDAKDGLPQKSSVKVNSALAM-----KQALPPRPVNAASPTNVQASSVYSVPAYT 1031
P + P+ +S S+L + K ALPP P + S S YT
Sbjct: 573 VLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPA-------LPRPSRSSPGLYT 625
Query: 1032 SPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV--APRPKFSAKKSGVTIQESGRS 1089
SP ++ P + SP P G SP S + S APRP FS + +G+ Q+ S
Sbjct: 626 SPGQ---DSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRES 681
Query: 1090 LS-----LPGRSVPPP-----ISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSP 1139
L PG S PP +S PW S SS P L W + SP
Sbjct: 682 LPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP--LPPPPPMSPSWSERSVSP 739
Query: 1140 LGLVDDAFQP-RNIQESIVANVVSAARRK 1167
L +A P R +Q + N+++AARRK
Sbjct: 740 LRPETEARPPSRQLQALLARNIINAARRK 768
Score = 49.3 bits (116), Expect = 2e-05
Identities = 98/473 (20%), Positives = 162/473 (34%), Gaps = 85/473 (17%)
Query: 484 LPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEES 543
L + +GKGA ++A+R+ RM++ + TP + + T L ++ Y +
Sbjct: 473 LSEASGKGAELYARRQSRMEKYVIESSSH----TPELARCPSPTMSLPSSWKYPTNAPGA 528
Query: 544 VRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPF 603
R S P + + G +P N +P P QP
Sbjct: 529 FRV----------ASRSPARTPPASLYHG---------YLPENGVLRPEP--TKQPPYQL 567
Query: 604 SPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS 663
P+ + SPI + P +A P + + P P P+P+ S P Y S
Sbjct: 568 RPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSR-SSPGLYTS 626
Query: 664 SERIASRDERISVP------AKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNS 717
+ + + +S P + + +P F+ + + SL +
Sbjct: 627 PGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP 686
Query: 718 EGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVS 777
GA + ++S G + + +PPP+ P P P+S
Sbjct: 687 PWT--PGASRPPSSLDGWVSPGP----WEPGRGSSMSSPPPLPPPP-----------PMS 729
Query: 778 PVWSP-GVAPTQPP--AFPTSNPSKGTVVSSI-KIAQPSYPPARPASTLNVAGPFKGPQA 833
P WS V+P +P A P S + + +I A+ R A N PF P+A
Sbjct: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPR-PFSPPRA 788
Query: 834 AVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTV 893
P P P + + QP G S +PG
Sbjct: 789 PPPP----PPPPPPPPRMRSPQPARPG-SAAVPGA------------------------- 818
Query: 894 QAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQ 946
A A +SP P+ P+S + PP + SP+ +L S+ S A+
Sbjct: 819 -AFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK 870
Score = 46.6 bits (109), Expect = 2e-04
Identities = 90/358 (25%), Positives = 132/358 (36%), Gaps = 81/358 (22%)
Query: 647 PPWPQPAPWSQPAFYDSSERIASRDERISVPAKRT-GILQEAKRRSTTKPMFTFKEPKVS 705
P P+ W P + R+ASR + PA G L E +P T K+P
Sbjct: 511 PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPE---NGVLRPEPT-KQPPYQ 566
Query: 706 PNPELLSLLQNSE-GKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPA 764
P L L E K A + P + + + + P P P+P+
Sbjct: 567 LRPSLFVLSPIKEPAKVSPRAASPAKPS---------SLDLVPNLPKGALPPSPALPRPS 617
Query: 765 VKS---------SSSQP----------VTPVSP--VWSPGVAPTQPPAFPTSNPSKGTVV 803
S S QP ++PVSP WSP P+F T N G
Sbjct: 618 RSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNA--GIEA 675
Query: 804 SSIKIAQPSYPP-----ARPASTLN---VAGPFK-GPQAAVASQNYTPKPTVSTPT---- 850
+ + P+ PP +RP S+L+ GP++ G ++++S P P +P+
Sbjct: 676 QDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSER 735
Query: 851 -VNAVQPG--AVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSL 907
V+ ++P A PS +L + R A+R+S + +A A++P P
Sbjct: 736 SVSPLRPETEARPPSRQLQALLARNIINAARRKSASPR-----------SAGAENPRPFS 784
Query: 908 PASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQP----SAAQPSKMGKKKGKKPLNA 961
P RAPPP P P P QP SAA P + PL A
Sbjct: 785 PP--------RAPPP----PPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPA 830
>gi|158303333 synaptopodin isoform B [Homo sapiens]
Length = 685
Score = 100 bits (249), Expect = 9e-21
Identities = 129/488 (26%), Positives = 196/488 (40%), Gaps = 137/488 (28%)
Query: 612 PIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRD 671
P+ +F APP Y+ ++P+A + PP S Y SS+ +S
Sbjct: 311 PLGNFTAPPTYTETLS---------TAPLASWVRSPP-------SYSVLYPSSDPKSSHL 354
Query: 672 ERISVPAKRTGILQEAK-RRSTTKPMFTFKE-PKVSPNPELLSLLQNSEGKRGTGAGGDS 729
+ +VPA +TGIL+E+ RR + K MFTF E PKV+PNP+LL L+Q ++ KR G+
Sbjct: 355 KGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEV 414
Query: 730 GPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789
G EE+ +LGAEA NF Q + + + P A + V P W+ + +
Sbjct: 415 GVEEEPFALGAEASNFQQEPAPRDRASPAAAEE-------------VVPEWASCLKSPRI 461
Query: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPK------ 843
A P P++ +S K A+ AR S + + + S ++TP+
Sbjct: 462 QAKPKPKPNQNLSEASGKGAELY---ARRQSRME--------KYVIESSSHTPELARCPS 510
Query: 844 PTVSTPT-----VNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAA 898
PT+S P+ NA PGA ++ P + S Y+ ++ ++
Sbjct: 511 PTMSLPSSWKYPTNA--PGAFRVASRSPART--------PPASLYHGYLPENGVLR---- 556
Query: 899 RAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKP 958
PT P + P +PI P+ K P AA P+K
Sbjct: 557 --PEPTKQPPYQLR-------PSLFVLSPIKEPA------KVSPRAASPAKP-------- 593
Query: 959 LNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTN 1018
++LD++ + P K ALPP P
Sbjct: 594 -SSLDLVPNLP---------------------------------KGALPPSPA------- 612
Query: 1019 VQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV--APRPKFSA 1076
+ S S YTSP ++ P + SP P G SP S + S APRP FS
Sbjct: 613 LPRPSRSSPGLYTSPGQ---DSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQAPRPSFST 668
Query: 1077 KKSGVTIQ 1084
+ +G+ Q
Sbjct: 669 RNAGIEAQ 676
Score = 36.6 bits (83), Expect = 0.16
Identities = 41/194 (21%), Positives = 71/194 (36%), Gaps = 26/194 (13%)
Query: 484 LPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEES 543
L + +GKGA ++A+R+ RM++ + TP + + T L ++ Y +
Sbjct: 473 LSEASGKGAELYARRQSRMEKYVIESSSH----TPELARCPSPTMSLPSSWKYPTNAPGA 528
Query: 544 VRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPF 603
R S P + + G +P N +P P QP
Sbjct: 529 FRV----------ASRSPARTPPASLYHG---------YLPENGVLRPEP--TKQPPYQL 567
Query: 604 SPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS 663
P+ + SPI + P +A P + + P P P+P+ S P Y S
Sbjct: 568 RPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSR-SSPGLYTS 626
Query: 664 SERIASRDERISVP 677
+ + + +S P
Sbjct: 627 PGQDSLQPTAVSPP 640
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 78.2 bits (191), Expect = 5e-14
Identities = 160/653 (24%), Positives = 225/653 (34%), Gaps = 107/653 (16%)
Query: 518 PSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGT-SET 576
P+ + A+ T + T +Y S S + VS P + G +G +
Sbjct: 771 PTEDSGASATASSKGTLTY---------LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI 821
Query: 577 ANIQRMV-PMNRTAKP-----FPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPD 630
N+ V P+ + P F GS + PAT SPT P + AP P SAVTP
Sbjct: 822 GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT-----PPSPKGAPTP-SAVTP--- 872
Query: 631 AFSRGVSSPIAGPAQPP-------PWPQ-----PAPWSQPAFYDSSERIASRDERISVPA 678
+GV+ P P + P P+P+ PAP PA +S +S + + PA
Sbjct: 873 LSPKGVTLP---PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS---SSPKKARATPA 926
Query: 679 KRTGILQEAKRRSTTKPMFTFKEPK---VSPNPELLSLLQNSEGKRGTGAGGDSGPEEDY 735
+ + + + T P T PK +P+P+ T GP
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA-----PTPPAATPPSPKGGP---- 977
Query: 736 LSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTS 795
+ S K PP A P+ K + P +P P V P P P +
Sbjct: 978 -----------ATPSPKGAPTPPAATPPSPKGGPATP-SPKGAPTPPAVTPPSPKGSPAA 1025
Query: 796 NP-SKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAV 854
P KG S+ A P P PA+T G P A + S PK +TP++
Sbjct: 1026 TPFPKG--ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS----PKGGPATPSLK-- 1077
Query: 855 QPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYS 914
GA P P G + + + M A P+ PA+ S
Sbjct: 1078 --GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135
Query: 915 --SNVRAPPP--VAYNPIHSPSYPLAALKSQPSAAQP-SKMGKKKGKKPLNALDVMKHQP 969
+ PPP P +P P L + P P + K A K P
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 970 YQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPA 1029
A+ PP K GL S A A PP P + + + + + PA
Sbjct: 1196 TTPAAT-----PPSPKGGLATPSP---KGAPTTPAATPPSPKGGLATPSPKGAP--TTPA 1245
Query: 1030 YTSPPSFFAEASSPVSASPV-PVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGR 1088
T P A+ P +P P P S K A+ + AP P S + G
Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS----PKGGP 1301
Query: 1089 SLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPLG 1141
+ S P + PP +T P S K + G PTP SP G
Sbjct: 1302 ATSPPKGAPTPPAATPP---------SPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Score = 77.0 bits (188), Expect = 1e-13
Identities = 159/647 (24%), Positives = 226/647 (34%), Gaps = 116/647 (17%)
Query: 589 AKPFPGSVNQP--ATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSP-IAGPAQ 645
A PFP + P ATP SP + + AP +A P P G ++P + G
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG---GPATPSLKGAPT 1081
Query: 646 PPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPK-- 703
PP P+P PA S + A + P+ + G+ + + T P T PK
Sbjct: 1082 PPAATPPSPKGGPA--TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139
Query: 704 -VSPNPE---LLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPV 759
+P P+ K G G + + + S K P
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
Query: 760 APKPAVKSSSSQP----------VTPVSP-----VWSPGVAPTQPPAFPTSNPSKGTVVS 804
A P+ K + P TP SP SP APT P A P S P G
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS-PKGGPATP 1258
Query: 805 SIKIAQPSYPPARPASTLN--VAGPFKG-PQAAVASQNYTPK--PTVSTPTVNAVQPGAV 859
K A P+ P A P S P KG P AV + +PK P S P P A
Sbjct: 1259 PPKGA-PTPPAATPPSLKGGLATPPHKGAPNPAVVTPP-SPKGGPATSPPKGAPTPPAAT 1316
Query: 860 GPSNE-LPGM-SGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYS--- 914
PS + PG +GA T A + TP+LPA+ S
Sbjct: 1317 PPSPKGSPGTPPPKGA-----------------PTPPAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 915 ----SNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPY 970
S+ P P A P H + + A PS G V+ P
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA------VIPLSPK 1413
Query: 971 QLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAA---SPTNVQASSVYSV 1027
+ A+ P ++G S + +L P +A P + ++
Sbjct: 1414 KAPAT------PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 1028 PAYTSP-------PSFFAEASSP--VSASPVPVG-------IPTSPKQESASSSYF---V 1068
PA T P P A +SSP A+P P+G IP+SPK+ A+ S +
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 1069 APRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKR 1128
AP +KK+ T+ P ++ PP T P S K T + +
Sbjct: 1528 APTATLLSKKTPATL--------APKEALIPPAMTVP---------SPKKTPAIPTPKEA 1570
Query: 1129 P-TPWEAAAKSPLGLVDDAFQ-PRNIQESIVANVVSAARRKVLPGPP 1173
P TP A SP + ++ + +E ++ V++ K P PP
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617
Score = 69.7 bits (169), Expect = 2e-11
Identities = 147/562 (26%), Positives = 187/562 (33%), Gaps = 81/562 (14%)
Query: 566 QQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAV 625
Q S TS + R P K P S + P P SP P P A
Sbjct: 907 QAPALSMTSSSPKKARATP---APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
Query: 626 TPP---PDAFSRGVSSPI-AGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPA-KR 680
TPP P + G ++P G PP P+P PA S + A ++ P+ K
Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA--TPSPKGAPTPPAVTPPSPKG 1021
Query: 681 TGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGA 740
+ + ++T P T PK SP L +G T A P+ G
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPL-----PKGAPTTPAATLPSPK------GG 1070
Query: 741 EACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800
A + S K PP A P+ K P TP SP AP P A P S KG
Sbjct: 1071 PA-----TPSLKGAPTPPAATPPSPKGG---PATP-----SPKGAPMPPAATPPS--PKG 1115
Query: 801 TVVSSIKIAQPSYPPARPASTLN--VAGPFKGPQAAVASQNYTPKPTVSTPTVNA--VQP 856
+ + P+ P A P S P KG A+ +PK ++TP P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 857 GAVGPSNE--LPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSL--PASWK 912
A PS + L S +GA AA SP L P+
Sbjct: 1176 AATPPSPKGGLATPSPKGAP-------------------TTPAATPPSPKGGLATPSPKG 1216
Query: 913 YSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQL 972
+ A PP + +PS P A + P+A PS G P A P L
Sbjct: 1217 APTTPAATPPSPKGGLATPS-PKGA-PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
Query: 973 NASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTS 1032
L T PP G P + V S PP+ A +P S P T
Sbjct: 1275 KGGLAT--PP--HKGAPNPAVVTPPSPKGGPATSPPK--GAPTPPAATPPSPKGSPG-TP 1327
Query: 1033 PPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSL 1092
PP + P P P G PT P +S P K T G
Sbjct: 1328 PPK--GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 1093 P-----GRSVPPPIS--TSPWV 1107
P G ++P P TSP V
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAV 1407
Score = 63.5 bits (153), Expect = 1e-09
Identities = 124/527 (23%), Positives = 175/527 (33%), Gaps = 92/527 (17%)
Query: 602 PFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPW---PQPAPWS-- 656
P T + + + P P +AV P A S + GP PPP PQ P S
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 657 -QPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSP--NPELLSL 713
Q + + S IAS + P +G A T TF + P +P L+L
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSG---TALPLGTAPEAPTFLPNLIGPPISPAALAL 118
Query: 714 LQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSS---- 769
G S P L+L A A + +Q SSA P AV S
Sbjct: 119 ASPMIAPTLKGTPSSSAP----LALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVIT 174
Query: 770 -SQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVS-----------SIKIAQPSYPPAR 817
S P+ P P + P++ P PS +VS SI+ S P
Sbjct: 175 LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT 234
Query: 818 PASTLNVAGP---------------------FKGPQAAVASQNYTPKPTVSTPTVNAVQP 856
P +TL +A P KGP + A+ + + T S P V + Q
Sbjct: 235 PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLS---TQSLPVVTSSQK 291
Query: 857 GAVGPSNELPGMSGRGAQLFAKRQS-------------------RMEKYVVDSDTVQAHA 897
A GP+ G+ L QS ++ VD + A
Sbjct: 292 TA-GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASY 350
Query: 898 ARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKK 957
+S P LP S N P VA P+ +PS PS
Sbjct: 351 PSQRSVIPPLP-----SRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPS--------- 396
Query: 958 PLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPT 1017
+L+V SL P+A P + + V+S + AA+PT
Sbjct: 397 --GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPT 454
Query: 1018 NVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASS 1064
+ P +S P E +SP + PV P P + A++
Sbjct: 455 TTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA-PKEPSTQVATT 500
Score = 62.4 bits (150), Expect = 3e-09
Identities = 125/560 (22%), Positives = 181/560 (32%), Gaps = 96/560 (17%)
Query: 584 PMNRTAKPFP-GSVNQPA-TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIA 641
P A P P G+ PA TP SP + +P P A TPP SP
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK--GAPTTPAATPP---------SPKG 1253
Query: 642 GPAQPPPWPQPAPWSQPAFYDSS---------ERIASRDERISVPAKRTGILQEAKRRST 692
GPA PPP P P PA S + A ++ P+ + G + +
Sbjct: 1254 GPATPPPKGAPTP---PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 693 TKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAK 752
T P T PK SP GT + + + +++
Sbjct: 1311 TPPAATPPSPKGSP---------------GTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 753 QKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIA-QP 811
K P P+ K + P S P + P P P KG S I P
Sbjct: 1356 SKGGPTT---PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 812 SYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNE----LPG 867
PA P + A P KG A TP P +A + G PS++ LP
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPA---VTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
Query: 868 MSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYS-SNVRAPPPVAYN 926
++ K ++ S +A A A P+LPA S V A P +
Sbjct: 1470 VTPPSP----KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 927 PIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKD 986
PI P A L S+ + P+ + K+ P T P
Sbjct: 1526 PIA----PTATLLSKKT---PATLAPKEALIP----------------PAMTVPSPKKTP 1562
Query: 987 GLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSA 1046
+P + K+A P V ++ + +P + PS + P
Sbjct: 1563 AIPTPKEAPATPS--SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Query: 1047 SPVPVGIPTSPKQESASSSYFVAP--------RPKFSAKKSGVTIQESGRSL-------S 1091
P P P +P + +S V P P K G T+ ++ + L +
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680
Query: 1092 LPGRSVPPPISTSPWVYQPT 1111
L V P ++P + PT
Sbjct: 1681 LKEVLVAPAPESTPIITAPT 1700
Score = 57.0 bits (136), Expect = 1e-07
Identities = 133/567 (23%), Positives = 185/567 (32%), Gaps = 68/567 (11%)
Query: 602 PFSPTRNMTSPIADFPAPP--PYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPA 659
P PT + P+A P P + + P+ + + P+ PP P
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPE-----IPKSVPSPSLPPAGTPPGTKKVDG 753
Query: 660 FYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEP---KVSPNPELLSLLQN 716
+S P + +G A + T + P VSP + +
Sbjct: 754 ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG 813
Query: 717 SEGKRGTGAGGDSGP----EEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQP 772
S G T G S P E +L + + + S A +P P +PK A S+ P
Sbjct: 814 SAGP-DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTP 872
Query: 773 VTPVSPVWSPGVAPTQ-------PPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVA 825
++P P PT P P + K S+ + P A PA A
Sbjct: 873 LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932
Query: 826 GPF-KGPQAAVASQNYTPK--PTVSTPTVNAVQPGAVGPSNE----LPGMSGRGAQLFAK 878
P KG A+ +PK P +P P A PS + P G A
Sbjct: 933 SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992
Query: 879 RQSRMEKYVVDSDTVQAHAARAQSPTP-SLPASWKYSSNVRAPPPVA-YNPIHSP-SYPL 935
S S P+P PA+ + PP +P SP + PL
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 936 -AALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSV 994
+ P+A PS G A +K P A+ PP K G P S
Sbjct: 1053 PKGAPTTPAATLPSPKGGP-------ATPSLKGAPTPPAAT-----PPSPKGG-PATPSP 1099
Query: 995 KVNSALAMKQALPPRPVNA-ASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASP-VPVG 1052
K A A PP P A+P + A + PA T P A+ P +P P
Sbjct: 1100 K--GAPMPPAATPPSPKGGLATPPHKGAP---TTPAATPPSPKGGLATPPPKGAPTTPAA 1154
Query: 1053 IPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTY 1112
P SPK A+ P PK + T L+ P P T+P P+
Sbjct: 1155 TPPSPKGGLAT------PPPKGAPTTPAATPPSPKGGLATPS---PKGAPTTPAATPPS- 1204
Query: 1113 SYSSKPTDGLEKANKRPTPWEAAAKSP 1139
P GL + + P AA P
Sbjct: 1205 -----PKGGLATPSPKGAPTTPAATPP 1226
Score = 53.1 bits (126), Expect = 2e-06
Identities = 122/520 (23%), Positives = 177/520 (34%), Gaps = 100/520 (19%)
Query: 593 PGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQP 652
P S P TP S + +P A P+ A+TPP + SP P P P
Sbjct: 1354 PSSKGGPTTPSS--KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL- 1410
Query: 653 APWSQPAFYDSSERIASRDERISVP---------------AKRTGILQEAKRRSTTKPMF 697
+P PA + E A+ + P A + G + + T P
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 698 TFKEPKVSPNPELLSLLQNSEGKRGTGAGGD---------SGPEEDYLSLGAEACNFMQS 748
T PK P P+ ++ + + T A S P+E + + +
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530
Query: 749 SSA-KQKTPPPVAPK----------------PAVKSSSSQPVTPVSPVWS--PGVAPTQP 789
++ +KTP +APK PA+ + P TP S S P V P+
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
Query: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
P+ P + + ++ P P PA T P KGP TP P TP
Sbjct: 1591 KGAPS--PKELLIPPAVTSPSPKEAPTPPAVT--PPSPEKGPA--------TPAPK-GTP 1637
Query: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPA 909
T V P ++ S P A + K + + + A P P
Sbjct: 1638 TSPPVTPSSLKDSPTSP------ASVTCKMGATVPQ------------ASKGLPAKKGPT 1679
Query: 910 SWKYSSNVRAP--PPVAYNPIH-SPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMK 966
+ K AP P+ P P ++ S P PS KG PL+ +
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG--PLSTV---- 1733
Query: 967 HQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNV-QASSVY 1025
A L Q +K + +S LA ++ P+ AA+ V
Sbjct: 1734 -----APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
Query: 1026 SVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSS 1065
SV A SPP S P++ SPVP PKQ+ SS
Sbjct: 1789 SVSAAPSPP-----VSLPLAPSPVPT---LPPKQQFLPSS 1820
Score = 47.4 bits (111), Expect = 9e-05
Identities = 87/340 (25%), Positives = 117/340 (34%), Gaps = 80/340 (23%)
Query: 583 VPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFP-----APPPYSAVTPP--------- 628
VP + P PATP S + +SP A P AP P + PP
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSS--KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612
Query: 629 -PDAFSRGVSSPIAGPAQPPP--WPQPAPWSQPAFYDSSERIASRDERIS---------V 676
P + SP GPA P P P P + + DS AS ++ +
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672
Query: 677 PAKR----------------TGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
PAK+ T I+ R+ + P + P+P S S+G
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP---SAKNGSKGP 1729
Query: 721 RGTGAGGDSGPEEDYLSLGAEACNFMQSSS-------AKQKTP------PPVAPKPAVKS 767
T A P + S A+ + S +K TP V PKP S
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESAS 1789
Query: 768 SSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYP----------PAR 817
S+ P PVS +P PT PP S G V+ S PS P P
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLES-----PSKPLAPADEDELLPLI 1844
Query: 818 PASTLNVAGPFKGPQAAVASQNYTPKPT-VSTPTVNAVQP 856
P ++ PF+ +V TPK + PT +A QP
Sbjct: 1845 PPEPISGGVPFQ----SVLVNMPTPKSAGIPVPTPSAKQP 1880
Score = 42.0 bits (97), Expect = 0.004
Identities = 106/490 (21%), Positives = 173/490 (35%), Gaps = 64/490 (13%)
Query: 637 SSPIAGPAQPPPWP-----QPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRS 691
S AGP PP +P AP Q +F + +S P +T + S
Sbjct: 289 SQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDH----S 344
Query: 692 TTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGG-DSGPEEDYLSLGAEACNFMQSSS 750
+T + + + P P ++ + A D GP ++ + C+ S S
Sbjct: 345 STGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPS----TISSITCS--PSGS 398
Query: 751 AKQKTPPPVAPKPAVKSSSSQPVT---------PVSPVWSPGVAPTQP---PAFPTSNPS 798
T ++P ++ SS T PVS V + + T P A PT+
Sbjct: 399 LNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE 458
Query: 799 KGTVVSSIKIAQPSYPP--ARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQP 856
T VS PP + P S + P A VA + P V+T V P
Sbjct: 459 VATCVS---------PPMSSGPISNIEPTSPAALVMAPVAPKE--PSTQVATTLRIPVSP 507
Query: 857 GAVGPSN--ELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYS 914
P + LP S + K+ D A+ +P A
Sbjct: 508 PLPDPEDLKNLPS-------------SVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTK 554
Query: 915 SNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQ--PYQL 972
+ P V P +SPS+ + + + + + KK +PL P +
Sbjct: 555 KDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGV 614
Query: 973 NASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTS 1032
N+S + D+ G P + + S+L + + P+ +A P V ++ YT+
Sbjct: 615 NSSASVIKT-DSYAG-PDSAGPLLKSSL-ITPTVAAFPLESADPAGVAPTTAKGTSTYTT 671
Query: 1033 PPSFFAEASSPVSASPVPV---GIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRS 1089
S F E + ++ PV + T P +AS + VAP P+ + +
Sbjct: 672 TASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIP 731
Query: 1090 LSLPGRSVPP 1099
S+P S+PP
Sbjct: 732 KSVPSPSLPP 741
Score = 32.3 bits (72), Expect = 2.9
Identities = 73/350 (20%), Positives = 114/350 (32%), Gaps = 87/350 (24%)
Query: 750 SAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIA 809
+ +Q+ P P A + SS+ VT + + PG PT PP +
Sbjct: 11 ATEQELPQPQAETAVLPMSSALSVT--AALGQPG--PTLPPPCSPA-------------- 52
Query: 810 QPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMS 869
P P S N A PF P ++ P P S+ T + P+ LP +
Sbjct: 53 ----PQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF-LPNLI 107
Query: 870 GRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIH 929
G P PA+ +S + AP
Sbjct: 108 G---------------------------------PPISPAALALASPMIAP---TLKGTP 131
Query: 930 SPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLP 989
S S PLA + P + Q K P N L + S+ T P A P
Sbjct: 132 SSSAPLALVALAPHSVQ------KSSAFPPNLLTSPPSVAVAESGSVITLSAPIA----P 181
Query: 990 QKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPV 1049
+ +N + + P P SP + V +VP + P + +
Sbjct: 182 SEPKTNLNK---VPSEVVPNPKGTPSPPCI----VSTVPYHCVTPM-----------ASI 223
Query: 1050 PVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPP 1099
G+ + P+ ++ +P+ K + S + ++ SLSL G PP
Sbjct: 224 QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 74.3 bits (181), Expect = 7e-13
Identities = 136/550 (24%), Positives = 196/550 (35%), Gaps = 98/550 (17%)
Query: 621 PYSAVTPPPDAFSRGVSSPIAGPAQPPPW----PQPAPWSQPAFYDSSERIASRDERISV 676
P + PPD S + +P++ PA PP P +P S P + ++S
Sbjct: 444 PSRPASTPPD--SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Query: 677 PAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYL 736
+ I+ + +S+ P P P L +L + T + + P +
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561
Query: 737 SLGAEACNFMQSSSAKQKTPPPVAPK----------PAVKSSSSQ--PVTPVSPVWSP-- 782
A +Q+ + TPPP P PA+ S Q P P+SP+ +P
Sbjct: 562 PCPAPCP--LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Query: 783 ------GVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVA 836
+ P Q P P ++P +S + P P A L PF P +
Sbjct: 620 QAPPXLALPPLQAPPSPPASPP----LSPLATPSPQAPNALAVHLLQA--PFSPPPSPPV 673
Query: 837 SQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAH 896
++P P V P A PS P ++ Q+
Sbjct: 674 QAPFSP------PASPPVSPSATPPSQAPPSLAAPPLQV--------------------- 706
Query: 897 AARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGK 956
SP S P S + +APPP+A P+ P P A+ PSA P ++
Sbjct: 707 ---PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
Query: 957 KPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVN--AA 1014
P L V P L S PP A L A QALP P +
Sbjct: 764 PP---LQVPPSPPASLPMSPLAKPPPQAPPAL----------ATPPLQALPSPPASFPGQ 810
Query: 1015 SPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKF 1074
+P + AS S P T PP + PV A+P+ + +P SP AS + RP
Sbjct: 811 APFSPSASLPMS-PLATPPPQ-----APPVLAAPL-LQVPPSP---PASPTLQAPRRPPT 860
Query: 1075 SAKKSGVTIQESGRSLSL---PGRSVPPPISTSPWVYQPTYS-YSSKPTDGLEKANKRPT 1130
+ V SG L+L PG PP S S + P + +SS T E+ +
Sbjct: 861 PGPDTSV----SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
Query: 1131 -PWEAAAKSP 1139
P AA SP
Sbjct: 917 GPEGGAAASP 926
Score = 63.9 bits (154), Expect = 9e-10
Identities = 90/372 (24%), Positives = 126/372 (33%), Gaps = 40/372 (10%)
Query: 584 PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGP 643
P+ P S+ P P +P + P+ P+PP TPPP A P+ P
Sbjct: 575 PLTTPPPETPSSIATPP-PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
Query: 644 AQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPK 703
PP P +P + P+ + A +LQ + P+ P
Sbjct: 634 PSPPASPPLSPLATPSPQAPN-------------ALAVHLLQAPFSPPPSPPVQAPFSPP 680
Query: 704 VSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKP 763
SP P S S+ A P S + TPPP AP P
Sbjct: 681 ASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPAS----------PPMSPSATPPPQAPPP 729
Query: 764 -AVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPAR-PAST 821
A P P SP SP P PP P ++++ + P PPA P S
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATP--PPRVP-------PLLAAPPLQVPPSPPASLPMSP 780
Query: 822 LNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQS 881
L P P A P P S P P A P + L + + A
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840
Query: 882 RMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRA---PPPVAYNPIHSPSYPLAAL 938
++ S T+QA R +P P S + A PPP + +P + S P A
Sbjct: 841 QVPPSPPASPTLQA-PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
Query: 939 KSQPSAAQPSKM 950
S + + P ++
Sbjct: 900 HSSSATSTPEEL 911
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/659 (23%), Positives = 222/659 (33%), Gaps = 92/659 (13%)
Query: 486 DTTGKGALMFAKRRERMDQITAQKEEDKVGGTPS----REQDAAQTD-GLRTTTSYQRKE 540
+T +G A +R + + GTPS R AA T+ GL R
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 541 EESVRTQSSVSK----SYIEVSHGLGHVPQQNGFSGTSETANIQRMV-PMNRTAKPFPGS 595
+ + SVS S E S P G + ++ P++ A+ P +
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 596 VNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPW 655
P P P++ P P A+ PP R ++P GP P P+P
Sbjct: 260 RGTPRAPAHPSQ---------PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 656 SQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQ 715
A R + + P T P P P+P LQ
Sbjct: 311 GTKA------RPVPPPDNAATPLPAT---------LPPSPPLATPLPLAPPSPSAPPSLQ 355
Query: 716 NSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTP 775
T P + S+ MQ+ + Q T PP+ ++ S S Q P
Sbjct: 356 TLPSPPAT------PPSQAPPSMTTPP---MQAPPSLQ-TIPPIQVPHSLTSPSLQ--AP 403
Query: 776 VSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSY-PPARPASTLNVAGPFKGPQAA 834
SP+ + T PT + + S + Q S P+RPAST + P + P +
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 835 VASQNYTPKPTVSTPTVNAV-QPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTV 893
AS P T +P V+ + P + P L ++ Q+ + ++
Sbjct: 464 PAS---PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP------QAPLSSLIMPPLET 514
Query: 894 QAHAA--RAQSPTPSLPASWKYSSNVRAPPPV--AYNPIHSPSY---------PLAALKS 940
Q+ A Q+P SL + APPP+ A P+ +P PL A S
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574
Query: 941 QPSAAQPSKMGKKKGKKPLNALDVMKHQPYQ----LNASLFTFQPPDAKDGLPQKSSVKV 996
P P + P A + P Q S PP A P ++
Sbjct: 575 -PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA----PPXLALPP 629
Query: 997 NSALAMKQALPP-RPVNAASPTNVQASSVYSVPAYTSPP-------SFFAEASSPVSASP 1048
A A PP P+ SP A +V+ + A SPP F AS PVS S
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 689
Query: 1049 VPVGIPTSPKQESASSSYFVAPRPKFS--AKKSGVTIQESGRSLSLPGRSVPPPISTSP 1105
P P+ A+ V P P S S ++ L+ P VPP SP
Sbjct: 690 TP---PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
Score = 59.7 bits (143), Expect = 2e-08
Identities = 137/629 (21%), Positives = 215/629 (34%), Gaps = 104/629 (16%)
Query: 595 SVNQPATPFSPTRNMTSPIADFPAPPPYSAV---TPPPDAFSRGVSSPIAGPAQPPPWPQ 651
++ + A PTR+ + + + PP S PP S G P++ P + +
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---PVSSPGRASGTTR 125
Query: 652 PAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRST------------------- 692
P P Q S+E +R + P KR+ + A+R ++
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAP-KRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 693 -------TKPMFTFKEPKVSPNPELLSLLQNS-------EGKRGTGAGGDSGPEEDYLSL 738
P + P P + S ++S +R + GG P LS
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 739 GAEACNF-------------------------MQSSSAKQKTPPPVAPKPAVKSSSSQPV 773
A + +Q+ Q TPP PA+ SS P+
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 774 TPVSPVWSPGVAPTQPP-----AFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPF 828
SP + P PP P + P + + + +A PS P+ P S + P
Sbjct: 305 ATPSPSGTK-ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS--PSAPPSLQTLPSPP 361
Query: 829 KGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVV 888
P + TP P + P++ + P V S P + + L S +
Sbjct: 362 ATPPSQAPPSMTTP-PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL--ALSSLQATTSL 418
Query: 889 DSDTVQA-HAARAQSPTPSLPASWKYSSNVRAPP--PVAYNPIHSPSYPLAALKSQPSAA 945
S T+QA H+ SP + + S PP P P+ P+ P P+
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV- 477
Query: 946 QPSKMGKKKGKKPLNAL-DVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQ 1004
S + PL AL + H P +SL PP L +SS+ S
Sbjct: 478 --SPLSSPLTIHPLQALSSLASHSPQAPLSSL--IMPP-----LETQSSLAPPSLQTPPA 528
Query: 1005 ALPPRPV----NAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE 1060
+L P+ + A P AS+ + P +PP A P+ A P P+ T+P E
Sbjct: 529 SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP---CPAPCPLQAPPSPL---TTPPPE 582
Query: 1061 SASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTD 1120
+ SS P P+ + +Q S L + PPP + P + S P
Sbjct: 583 TPSS--IATPPPQAPPALASPPLQ-GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 1121 GLEKANKRPTPWEAAAKSPLGLVDDAFQP 1149
P+P +A + L+ F P
Sbjct: 640 PPLSPLATPSP-QAPNALAVHLLQAPFSP 667
Score = 59.7 bits (143), Expect = 2e-08
Identities = 126/572 (22%), Positives = 191/572 (33%), Gaps = 123/572 (21%)
Query: 584 PMNRTAKPF--PGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIA 641
P+ + P P P P + SP+ P P S TPPP A S P+
Sbjct: 545 PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604
Query: 642 GPAQPP--PWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTF 699
G PP P P P + P +++P LQ + P+
Sbjct: 605 GLPSPPLSPLATPPPQAPP--------------XLALPP-----LQAPPSPPASPPL--- 642
Query: 700 KEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPV 759
P +P+P+ + L A + +Q+ +PPP
Sbjct: 643 -SPLATPSPQAPNAL---------------------------AVHLLQAPF----SPPPS 670
Query: 760 APKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPA 819
P A S + P PVSP +P P+Q P PS + + P+ PP P+
Sbjct: 671 PPVQAPFSPPASP--PVSPSATP---PSQAP------PSLAAPPLQVPPSPPASPPMSPS 719
Query: 820 STLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKR 879
+T P P A P P S P + P A P P ++ Q+
Sbjct: 720 ATPPPQAP---PPLAAPPLQVPPSPPASPP----MSPSATPPPRVPPLLAAPPLQVPPSP 772
Query: 880 QSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALK 939
+ + + QA A A P +LP+ PP ++ P +P P A+L
Sbjct: 773 PASLPMSPLAKPPPQAPPALATPPLQALPS-----------PPASF-PGQAPFSPSASLP 820
Query: 940 SQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSA 999
P A P + P+ A +++ P AS P P S
Sbjct: 821 MSPLATPPPQ------APPVLAAPLLQVPP-SPPASPTLQAPRRPPTPGPDTSVSGPRLT 873
Query: 1000 LAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQ 1059
LA+ PP P + S T S P +SS S G + P+
Sbjct: 874 LALAPGPPPPPSRSPSST-------------LSGPDLAGHSSSATSTPEELRGYDSGPEG 920
Query: 1060 ESASSSYFVAPRPKFSAKKSGVTIQESGRSLSL---PGRSVPPPISTSP-------WVYQ 1109
+A+S P + +A + L+ PG +P P +T P +Y+
Sbjct: 921 GAAASP---PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 977
Query: 1110 PTYSYSSKPTDGLEKANKRPTPWEAAAKSPLG 1141
S+ P G + P+P + K+ G
Sbjct: 978 TEGPESATPAPG--ALDPGPSPGTSGGKAAAG 1007
Score = 57.8 bits (138), Expect = 7e-08
Identities = 143/648 (22%), Positives = 221/648 (34%), Gaps = 100/648 (15%)
Query: 588 TAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPP 647
T+ P PG+ P+ + P P P + PP + + VSS
Sbjct: 164 TSGPTPGT---PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS---ASEHST 217
Query: 648 PWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPN 707
P PA +P+ +R ASR S+ + T + A+ + + P
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASR----SLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273
Query: 708 PELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPP---------- 757
P+ L L+ + T D+ P LS A + A+ PP
Sbjct: 274 PKGLQALRPPQV---TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT 330
Query: 758 -----PVA-PKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQP 811
P+A P P S S P + + P P+Q P T+ P + A P
Sbjct: 331 LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ---------APP 381
Query: 812 S---YPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGM 868
S PP + +L + + P + +A + ++ +PT+ A ++ M
Sbjct: 382 SLQTIPPIQVPHSL-TSPSLQAPPSPLALSSLQATTSLGSPTLQA--------THSFLTM 432
Query: 869 SGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSP---TPSLPASWKYSSNVRAPPPVAY 925
S R Q SR DS +QA + SP T PA SS + P A
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
Query: 926 NPI--HSPSYPLAA-----LKSQPSAAQPSKMGKKKG--KKPLNALDVMKHQPYQLNA-- 974
+ + HSP PL++ L++Q S A PS PL L + P Q +
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
Query: 975 ---------------------SLFTFQPPDAKDGL----PQKSSVKVNSALAMKQALPPR 1009
S T PP+ + PQ + L Q LP
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL---QGLPSP 609
Query: 1010 PVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVS--ASPVPVGIPTSPKQESASSSYF 1067
P++ + QA ++P +PPS AS P+S A+P P P + + +
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPS--PPASPPLSPLATPSPQA-PNALAVHLLQAPFS 666
Query: 1068 VAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANK 1127
P P A S S + P ++ PP ++ P P+ S + +
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 1128 RPTPWEAAAKS--PLGLVDDAFQPRNIQESIVANVVSAARRKVLPGPP 1173
P P A P P V +++A +V P PP
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
Score = 35.0 bits (79), Expect = 0.45
Identities = 81/372 (21%), Positives = 129/372 (34%), Gaps = 53/372 (14%)
Query: 754 KTPPPVAPKPAVKSSSSQPVTPVS--PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQP 811
+ P + P+P PVTP + + + G +P A T+ S P
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA----P 75
Query: 812 SYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGR 871
P R A T + P P A+ + P S V++ PG + + +
Sbjct: 76 RAGPTRSAGTSS-RNPASRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRPGPLGQK 132
Query: 872 GAQLFAKRQSRMEKYVV--DSDTVQAHAARAQS-PTPSLPA------SWKYSSNVRAPPP 922
G ++ A+ K + A A R S PTP P+ S + V P P
Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 923 VAYN----PIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFT 978
P P +++ S+ S +PS +++ P + + L++S
Sbjct: 193 APSARPRPPTEGPRKSVSSA-SEHSTTEPSPAARRR---PSAGGGLQRPASRSLSSSATP 248
Query: 979 FQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFA 1038
P A+ G + + + A P +P P +QA P T P A
Sbjct: 249 LSSP-ARSGPSARGTPRA-------PAHPSQP----KPKGLQA---LRPPQVTPPRKDAA 293
Query: 1039 EASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQES-----GRSLSLP 1093
A P+S+SP+ P+ K P P +A T+ S L+ P
Sbjct: 294 PALGPLSSSPLATPSPSGTKARP-------VPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 1094 GRSVPPPISTSP 1105
S PP + T P
Sbjct: 347 SPSAPPSLQTLP 358
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 71.2 bits (173), Expect = 6e-12
Identities = 120/517 (23%), Positives = 184/517 (35%), Gaps = 70/517 (13%)
Query: 584 PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFP--APPPYSAVTPPPDA--FSRGVSSP 639
P ++ P PA+P +++ P+ + P PP S ++PPP++ FS SP
Sbjct: 460 PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP 519
Query: 640 IAGPAQPPPWP------QPAPWSQPAF--YDSSERIASRDERISVPAKRTGILQEAKRRS 691
++ P + PP P P P + P ++ S +E + P L S
Sbjct: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
Query: 692 TTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSA 751
P +E +SP PE L E + PEE LS EA
Sbjct: 580 PMSP--PPEESPMSPPPEASRLFPPFE-----ESPLSPPPEESPLSPPPEASRLSPPPED 632
Query: 752 KQKTPP----PVAPKPAVKSSSSQP-VTPVSPVWSPGVAPTQPP--AFPTSNPSKGTVVS 804
+PP P++P P V S P V+ +SP P +P PP PTS P + + +S
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP--PPEESPLSPPPEESPTSPPPEASRLS 690
Query: 805 SIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNE 864
P+ PP P P + + P +P + + + P +E
Sbjct: 691 PPPEDSPTSPP-----------PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE 739
Query: 865 LPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVA 924
P +S R + R E+ + + H SP P P V
Sbjct: 740 GPHLSPRPEE--PHLSPRPEEPHLSPQAEEPHL----SPQPEEPCLC----------AVP 783
Query: 925 YNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDA 984
P SP L QP S ++ P+ + QP + + S + +P
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP--C 841
Query: 985 KDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSP--PSFFAEASS 1042
P++S + S K L PRP Q + +P + P PS
Sbjct: 842 LSPRPEESHL---SPELEKPPLSPRPEKPPEEPG-QCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 1043 PVSA-------SPVPVGIPTSPKQESASSSYFVAPRP 1072
P + SP+P +P SP E + S + P P
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934
Score = 57.8 bits (138), Expect = 7e-08
Identities = 91/402 (22%), Positives = 135/402 (33%), Gaps = 67/402 (16%)
Query: 601 TPFSPTRNMTSPIADFP-APPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPA 659
+P ++ P + P +PPP + T PP SR P P PPP PA S P
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA--SPP- 710
Query: 660 FYDSSERIASRDERISVPAKRTGIL------QEAKRRSTTKPMFTFKEPKVSPNPELLSL 713
D +S+P + + +L Q R +EP +SP PE L
Sbjct: 711 ---------PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL 761
Query: 714 LQNSEGKRGTGAGGD----SGPEEDYLSLGAEACNFMQSSSAKQKTP----PPVAPKPAV 765
+E + + + PEE +LS AE + +P P ++P P
Sbjct: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
Query: 766 KSSSSQP---------------------------------VTPVSPVWSPG--VAPTQPP 790
S QP P P PG AP + P
Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881
Query: 791 AF-PTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
F P PS ++ +++P PP P P P + P P +P
Sbjct: 882 LFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP 941
Query: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPA 909
+ A P A+ P EL GA+ + +S + ++++ A P P P
Sbjct: 942 IITAAAPPALSPLGELE--YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM 999
Query: 910 SWKYS--SNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSK 949
S S V P+ P+ PL P + PS+
Sbjct: 1000 ILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQ 1041
Score = 57.0 bits (136), Expect = 1e-07
Identities = 130/546 (23%), Positives = 192/546 (35%), Gaps = 96/546 (17%)
Query: 601 TPFSPTRN---MTSPIADFP-APPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWS 656
TP SP ++ P + P +PPP T PP SR P P PP P+ +P S
Sbjct: 534 TPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP--PEESPMS 591
Query: 657 QPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQN 716
P EA R F+E +SP PE L
Sbjct: 592 PP--------------------------PEASRLFP-----PFEESPLSPPPEESPLSPP 620
Query: 717 SEGKRGTGAGGDS----GPEEDYLSLGAEACNFMQSSSAKQKTPP----PVAPKPAVKSS 768
E R + DS PEE +S E + +PP P++P P +
Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 769 SSQP-VTPVSPVWSPGVAPTQPPA--FPTSNPSKGTVVSSIKIAQPSYP-PARPASTLNV 824
S P + +SP P +PT PP P S P + +++S P P P P
Sbjct: 681 SPPPEASRLSP--PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
Query: 825 AGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQS--- 881
GP P+ + +P+P + A +P + P E P + + Q+
Sbjct: 739 EGPHLSPRP--EEPHLSPRPEEPHLSPQAEEP-HLSPQPEEPCLCAVPEEPHLSPQAEGP 795
Query: 882 ----RMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSP----SY 933
+ E+ + T + H SP P P P + P SP S+
Sbjct: 796 HLSPQPEELHLSPQTEEPHL----SPVPEEPCLSPQPEESHLSPQ-SEEPCLSPRPEESH 850
Query: 934 PLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSS 993
L+ P + +P K ++ G+ P P +L F PP G P S
Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCP---------APEELP----LFPPP----GEPSLSP 893
Query: 994 VKVNSALAMKQALPPRPVN---AASPTNVQASSVYSVPAYTSPP--SFFAEASSPVSASP 1048
+ AL+ P P+ SP+ + S +P PP S A++P + SP
Sbjct: 894 LLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSP 953
Query: 1049 V-PVGIPTSPKQESASSSYFVAP---RPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTS 1104
+ + P K +S S AP P ++ T E + LP P S
Sbjct: 954 LGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPAS 1013
Query: 1105 PWVYQP 1110
P + +P
Sbjct: 1014 PILMEP 1019
Score = 47.4 bits (111), Expect = 9e-05
Identities = 148/661 (22%), Positives = 220/661 (33%), Gaps = 132/661 (19%)
Query: 587 RTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPP---------------DA 631
R +P P P+ P P D A PP + PP D
Sbjct: 2348 RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP 2407
Query: 632 FSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS--SERIASRDERISVPAKRTGILQEAKR 689
FSR +SP + + P P P S AF S + R S D P++ +
Sbjct: 2408 FSRVPASPQSQSSSQSPL-TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR-------PQS 2459
Query: 690 RSTTKPMFTFKEPKVSPNPELL----SLLQNSEGKRGTGAGGDSGPEEDYLSL--GAEAC 743
R P+ K P+ P PE+ SL S G G A +GP + + +
Sbjct: 2460 RDPFAPL--HKPPRPQP-PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPP 2516
Query: 744 NFMQS---------SSAKQKTPPPVAPKPAVKSSSSQPVTP----VSPVWSPGVAPTQP- 789
NF++S S + T P +P++K QP P ++ + PG +P
Sbjct: 2517 NFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQ 2576
Query: 790 ------------PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVAS 837
P+ PS G+ S ++ P RP S L P S
Sbjct: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLS-----PLRPPSVLPPPAP--DGSLPYLS 2629
Query: 838 QNYTPKPTVSTPTVNAVQPG---------AVGPSNELPGMSGRG-AQLFAKRQSRMEKYV 887
+ + +++P PG A P + PGMSG +L +RQ + + +
Sbjct: 2630 HGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLREL 2689
Query: 888 VDSDTVQAHAARAQSPTPSL-------PASW-----------------------KYSSNV 917
+ +Q + R + T + P SW SS V
Sbjct: 2690 LIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLV 2749
Query: 918 RAPPPVAYNPIHSP-SYPL-AALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNAS 975
PP PI P S+P L P A PS M + + + PY +
Sbjct: 2750 GLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLP 2809
Query: 976 LFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRP---VNAASPTNVQASSVYSVPAYTS 1032
L Q + Q+++ + AM P P + + + A +P
Sbjct: 2810 L---QQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGE 2866
Query: 1033 P------PSFFAEASSPVSASPVPVGIP---TSPKQESASSSYFVAPRPKFSAKKSGVTI 1083
P P+ F E V P G P P Q Y V+ P A + +
Sbjct: 2867 PVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR--PRFYPVSEDPHRLAPEGLRGL 2924
Query: 1084 QESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPT--DGLEKANKRPTPWEAAAKSPLG 1141
SG P P ++ S PT ++ PT GLE N+ P+ E +PL
Sbjct: 2925 AVSGLPPQKPSAPPAPELNNS---LHPT-PHTKGPTLPTGLELVNRPPSSTELGRPNPLA 2980
Query: 1142 L 1142
L
Sbjct: 2981 L 2981
Score = 46.6 bits (109), Expect = 2e-04
Identities = 129/611 (21%), Positives = 205/611 (33%), Gaps = 88/611 (14%)
Query: 573 TSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFP--APPPYSAVTPPPD 630
TS R+ P + P P +P + P + P PP S ++PPP+
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 631 AFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRR 690
A SR P P PP P+ +P S P + R+S P + + + +
Sbjct: 623 A-SRLSPPPEDSPMSPP--PEESPMSPPPEVSRLSPLPV-VSRLSPPPEESPLSPPPEES 678
Query: 691 STTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSS 750
T+ P + ++SP PE + + PE+ +SL E +
Sbjct: 679 PTSPPP---EASRLSPPPE-----DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 751 AKQKTP----PPVAPKPAVKSSSSQPVTP------VSPVWSPG-------VAPTQPPAFP 793
Q P P ++P+P S +P P P SP P +P P
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790
Query: 794 TS-----NPSKGTVVSSIKIAQP--SYPPARPASTLNVAGPFKGPQAAVASQNYTP---- 842
+ +P + S + +P S P P + PQ+ + P
Sbjct: 791 QAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH 850
Query: 843 ------KPTVS-TPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQA 895
KP +S P +PG ELP LF ++ +
Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCPAPEELP--------LFPPPGEPSLSPLLGEPALSE 902
Query: 896 HAARAQSPTPS---LPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKM-- 950
SP P L S + S + + PP +P+ P P+ + P+ + ++
Sbjct: 903 PGEPPLSPLPEELPLSPSGEPSLSPQLMPP---DPLPPPLSPIITAAAPPALSPLGELEY 959
Query: 951 -----GKKKGKKPLNA--LDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSAL-AM 1002
G + PL A L+ P + N + PP LP V A +
Sbjct: 960 PFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI---LPPSPGSPVGPASPIL 1016
Query: 1003 KQALPPRPVNAASPTNVQASSV--YSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE 1060
+ LPP+ SP +Q S V S P+ SPP+ SP+S VG+ +
Sbjct: 1017 MEPLPPQ----CSPL-LQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELH 1071
Query: 1061 SASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTD 1120
+ P + + LS P S P + + + T P D
Sbjct: 1072 EMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDT-----APLD 1126
Query: 1121 GLEKANKRPTP 1131
G++ +P P
Sbjct: 1127 GIDAPGSQPEP 1137
Score = 44.7 bits (104), Expect = 6e-04
Identities = 114/492 (23%), Positives = 171/492 (34%), Gaps = 100/492 (20%)
Query: 511 EDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSK----SYIEVSHGL-GHVP 565
E K+ GTPS ++DAA L T +R ++ S R SS K + S L +
Sbjct: 4499 EQKLQGTPSNKEDAAARKPL--TPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLK 4556
Query: 566 QQNGFSGTSE---TANIQRMVPMNRTA-----KPFPGSVNQPATPFSPT--------RNM 609
Q+ +E TAN P G+ A P P N+
Sbjct: 4557 QELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNL 4616
Query: 610 TSPIADFPAPPPYSAVTPPPDAFSRGVS--SPIAGPAQPPPWPQPAPWSQPAFYDSSERI 667
++P P PP TPPP + V+ +P + P A S+ A D+SE +
Sbjct: 4617 SNP----PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSE-V 4671
Query: 668 ASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGG 727
S D ++P ++ + S E SP+ + +
Sbjct: 4672 KSLDLLAALPTPPHNQTEDVRMESD--------EDSDSPDSIVPA--------------- 4708
Query: 728 DSGPEEDYLSLGAEACNFMQSSSAK-QKTPPPVAPKPAVKSSSSQPVTP-VSPVWSPGVA 785
S PE LG EA F S + ++ ++P + +S PV P P + G+
Sbjct: 4709 -SSPES---ILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLE 4764
Query: 786 PTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPT 845
T KG+ VS + A A LN G AVA P
Sbjct: 4765 VPGKLPVTTWEKGKGSEVSVMLTVS-----AAAAKNLN------GVMVAVAELLSMKIPN 4813
Query: 846 V------STPTVNAVQPG---AVGPSNELPGMSGR----GAQLFAKRQSRMEKYVVDSDT 892
+P +P A GP + G+ G+ G + + + Y + S
Sbjct: 4814 SYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQL 4873
Query: 893 VQAHAARAQSPTPSLPASWKYSSNVR--------APPP---------VAYNPIHSPSYPL 935
+ +SP P P Y+ NV APPP +A +P P+ PL
Sbjct: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPL 4933
Query: 936 AALKSQPSAAQP 947
L ++P A P
Sbjct: 4934 VELPTEPLAEPP 4945
Score = 36.6 bits (83), Expect = 0.16
Identities = 109/521 (20%), Positives = 168/521 (32%), Gaps = 138/521 (26%)
Query: 617 PAPPPYSAVTPPPD-AFSRGVSSP-IAGPAQPP--PWPQPAPWSQPAFYDSSERIASRDE 672
PAP PP + + S + P ++ P +PP P P+ P S S ++ D
Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934
Query: 673 RISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPE 732
+P + I+ A P +SP EL + GA GDS PE
Sbjct: 935 ---LPPPLSPIITAAA------------PPALSPLGEL---------EYPFGAKGDSDPE 970
Query: 733 EDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAF 792
S A P++P P + +PV P+ SPG +P P
Sbjct: 971 ---------------SPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG-SPVGP--- 1011
Query: 793 PTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVN 852
+S + +P P P Q ++ QN +P S P +
Sbjct: 1012 -----------ASPILMEPLPPQCSPLL-----------QHSLVPQN-SPPSQCSPPALP 1048
Query: 853 AVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPT-PSLPASW 911
P + P ++ G+S D + H + + P PA
Sbjct: 1049 LSVPSPLSPIGKVVGVS---------------------DEAELHEMETEKVSEPECPAL- 1086
Query: 912 KYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQP-- 969
P A +P+ SP L+ P+ A G + PL+ +D QP
Sbjct: 1087 ---------EPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP 1137
Query: 970 --------YQLNASLFTFQPPD-----AKDGLPQKSSVKVNSALAMKQALPPRPVNAASP 1016
+L S P + + P+ + +Q P PV P
Sbjct: 1138 GQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPP 1197
Query: 1017 TNVQASSVYSVPAYT-SPPSFFAEASSPVSASPVP---------VGIPT--SPKQESASS 1064
T +++ V + + S S P+ SP P +G+ T SP ++ S
Sbjct: 1198 TLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSL 1257
Query: 1065 SYFVAPRPKF---------SAKKSGVTIQESGRSLSLPGRS 1096
P+ +A G E GR S P RS
Sbjct: 1258 RLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARS 1298
Score = 35.0 bits (79), Expect = 0.45
Identities = 113/550 (20%), Positives = 168/550 (30%), Gaps = 118/550 (21%)
Query: 591 PFPGSVNQPATPFSPTRNMTSPIA----------------------DFPA------PPPY 622
P PG++ P +PT + SP D P PP
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
Query: 623 SAVTPPPDAFSRGVSSPI-----AGPAQPPPWPQP--APWSQPAFYDSSERIASRDERIS 675
A P D F + P+ P PP+P P AP P SS A +
Sbjct: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFH 2227
Query: 676 VPAKRTGILQEAKRRSTTKPMF-----------------TFKEPKVSPNP--ELLSLLQN 716
T Q + KP EP +SP P E L+
Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEV 2287
Query: 717 SEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPV 776
+ + G + P ++ + + + KTP ++S +P +P
Sbjct: 2288 KKEELGASSPSYGPPNLGFVDSPSSGTHL---GGLELKTPDVFKAPLTPRASQVEPQSP- 2343
Query: 777 SPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA-RPASTLNVAGPFKGPQAAV 835
G+ P +PP PS PS+P RP S P+ P
Sbjct: 2344 ----GLGLRPQEPPPAQALAPS-----------PPSHPDIFRPGS---YTDPYAQPP--- 2382
Query: 836 ASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQA 895
TP+P P P PS+ + Q + QS + T +
Sbjct: 2383 ----LTPRPQPPPPESCCALPPRSLPSDPFSRVPA-SPQSQSSSQSPL--------TPRP 2429
Query: 896 HAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKG 955
+A A P+P P ++P P + P S A +P QP ++ K G
Sbjct: 2430 LSAEAFCPSPVTP-------RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAG 2482
Query: 956 KKPLNALD-------VMKHQPYQLNASLFTFQPPD--------AKDGLPQKSSVKVNSAL 1000
+L + +L+A + + QPP+ A G P A+
Sbjct: 2483 SLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAV 2542
Query: 1001 AMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQE 1060
PP P P + S P P S + + + P G P P
Sbjct: 2543 GEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQS---TNYTVATGNFHPSGSPLGPSSG 2599
Query: 1061 SASSSYFVAP 1070
S SY ++P
Sbjct: 2600 STGESYGLSP 2609
Score = 32.0 bits (71), Expect = 3.8
Identities = 36/139 (25%), Positives = 48/139 (34%), Gaps = 21/139 (15%)
Query: 521 EQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQ 580
++ Q+ +R T YQ ++ Q LG PQ GF G +T +Q
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGL-----------LGCQPQLGGFPGP-QTGPLQ 4275
Query: 581 RMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIAD--FPAPPPYSAVTPPPDAFSRGVSS 638
+ R P P P P T P+ P PPP S P + SS
Sbjct: 4276 ELGAGPRPQGP-------PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 639 PIAGPAQPPPWPQPAPWSQ 657
+ AQ PP P Q
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQ 4347
Score = 30.8 bits (68), Expect = 8.5
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 12/64 (18%)
Query: 607 RNMTSPIADFPAPPPY----SAVTPPPDAFSRGVSSPIAGPAQPPPWP--------QPAP 654
R +++P + P+PPP S +PP + + P+A P P P P +P P
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Query: 655 WSQP 658
++P
Sbjct: 4964 RARP 4967
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 71.2 bits (173), Expect = 6e-12
Identities = 47/169 (27%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
I + G PWGFRL GGK+ +QPL ++++ SKA+ + LC GD + +I+G +++T+ E
Sbjct: 6 IDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++ TD+L + + R + L++E E K + + L I A
Sbjct: 66 AQNRIKGCTDNLTLTVARSEHKVWSPLVTE-EGKRHPYKMNLASEPQEVLHIGSAHNRSA 124
Query: 129 TEFFLAPV-KTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRG 176
F +P T + NQ + P AG E ++ A + + G
Sbjct: 125 MPFTASPASSTTARVITNQYNNP--AGLYSSENISNFNNALESKTAASG 171
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 69.7 bits (169), Expect = 2e-11
Identities = 143/567 (25%), Positives = 205/567 (36%), Gaps = 88/567 (15%)
Query: 588 TAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPP 647
T+ P PG+ P+ + P P P + PP + + VSS
Sbjct: 164 TSGPTPGT---PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS---ASEHST 217
Query: 648 PWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPN 707
P PA +P+ +R ASR S+ + T + A+ + + P
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASR----SLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273
Query: 708 PELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKS 767
P+ L L+ + T D+ P LS A S++ + + PP + P S
Sbjct: 274 PKGLQALRPPQV---TPPRKDAAPALGPLSSSPLATP-SPSAALQSQAPPTLPATPHSSS 329
Query: 768 SSSQPVTPVSPVWSPGVAPTQPPAF------PTSNPSKGTVV--SSIKIAQPSYPPARPA 819
+ Q TP+ P+ P +P+ PP+ P + PS+ T S A S+ P+ P
Sbjct: 330 LTCQLATPL-PLAPP--SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386
Query: 820 STLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKR 879
S L P P A+ P P S P P P+ A
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN------------ALAVH 434
Query: 880 QSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALK 939
+ S VQA SP S P S + +APP +A P+ P P A+
Sbjct: 435 LLQAPFSPPPSPPVQAPF----SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 490
Query: 940 SQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSA 999
PSA P + PL A + +P PP A L A
Sbjct: 491 MSPSATPP-----PQAPPPLAAPPLQLAKP-----------PPQAPPAL----------A 524
Query: 1000 LAMKQALPPRPVN--AASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSP 1057
QALP P + +P + AS S P T PP + PV A+P+ + +P SP
Sbjct: 525 TPPLQALPSPPASFPGQAPFSPSASLPMS-PLATPPPQ-----APPVLAAPL-LQVPPSP 577
Query: 1058 KQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSL---PGRSVPPPISTSPWVYQPTYS- 1113
AS + RP + V SG L+L PG PP S S + P +
Sbjct: 578 ---PASPTLQAPRRPPTPGPDTSV----SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630
Query: 1114 YSSKPTDGLEKANKRPT-PWEAAAKSP 1139
+SS T E+ + P AA SP
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASP 657
Score = 63.5 bits (153), Expect = 1e-09
Identities = 127/560 (22%), Positives = 196/560 (35%), Gaps = 59/560 (10%)
Query: 595 SVNQPATPFSPTRNMTSPIADFPAPPPYSAV---TPPPDAFSRGVSSPIAGPAQPPPWPQ 651
++ + A PTR+ + + + PP S PP S G P++ P + +
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---PVSSPGRASGTTR 125
Query: 652 PAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELL 711
P P Q S+E +R + P + L RR T+ P +P+P +
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAP--KRSALSAGARRDTSGP------TPGTPSPAMA 177
Query: 712 SLLQNSEGKRGTGAGGDS--------GPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKP 763
+ + + G S GP + S + ++ ++ + +P
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 764 AVKSSSSQPVTPVSPVWSPGVAPTQP--PAFPTSNPSKGTVVSSIKIAQPSYPPARPAST 821
A +S SS SP S A P PA P+ KG P A PA
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
Query: 822 LNVAGPFKGPQAAVASQNYTPKPTVSTP-----TVNAVQPGAVGPSNELPGMSGRGAQLF 876
+ P P + A Q+ P +TP T P + P + S +
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357
Query: 877 AKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLA 936
+ S T+QA S PS P S + +APP +A P+ +P P A
Sbjct: 358 PATPPSQATTSLGSPTLQA----THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413
Query: 937 ALKSQPSAAQPSKMGKKKGKKPLNALDV-MKHQPYQLNASLFTFQPPDAKDGLPQKSSVK 995
+ P A PS NAL V + P+ S P P S
Sbjct: 414 SPPLSP-LATPSPQAP-------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
Query: 996 VNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPT 1055
S A PP V + P + S P+ T PP +A P++A P+ + P
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMS-----PSATPPP----QAPPPLAAPPLQLAKP- 515
Query: 1056 SPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVP----PPISTSPWVYQPT 1111
P+ A ++ + P A G SL + + P PP+ +P + P
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575
Query: 1112 YSYSSKPTDGLEKANKRPTP 1131
S + PT L+ + PTP
Sbjct: 576 -SPPASPT--LQAPRRPPTP 592
Score = 53.5 bits (127), Expect = 1e-06
Identities = 100/422 (23%), Positives = 145/422 (34%), Gaps = 60/422 (14%)
Query: 573 TSETANIQRMVPMNRTAKPFPGSV-NQPATPFSP-TRNMTSPIAD-----FPAPPPYSAV 625
T + A + P + +A P ++ + PATP S T ++ SP P+PP
Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390
Query: 626 TPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQ 685
TPPP A P+ P PP P +P + P+ + A +LQ
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN-------------ALAVHLLQ 437
Query: 686 EAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAG----GDSGPEEDYLSLGA- 740
+ P+ P SP P S S+ A S P +S A
Sbjct: 438 APFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496
Query: 741 ---EACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPA------ 791
+A + + + PPP AP PA+ + Q + P P PG AP P A
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQAL-PSPPASFPGQAPFSPSASLPMSP 554
Query: 792 FPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYT---------- 841
T P V+++ + P PPA P P GP +V+ T
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614
Query: 842 ----PKPTVSTPTVNAVQPGAVGPSNELPGM-SGRGAQLFAKRQSRMEKYVVDSDTVQAH 896
P T+S P + A EL G SG A D++ H
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP-------DAELAACH 667
Query: 897 AARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGK 956
A A S P+ P +++ + P P A P + P +A P+ G
Sbjct: 668 PA-AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726
Query: 957 KP 958
P
Sbjct: 727 SP 728
Score = 37.4 bits (85), Expect = 0.091
Identities = 79/337 (23%), Positives = 116/337 (34%), Gaps = 71/337 (21%)
Query: 574 SETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAP---PPYSAVTPPPD 630
S +A P + A P + PA+P P +P P P PP PPP
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
Query: 631 AFSRGVSSPI-AGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISV------------P 677
A + P+ A P+ P +P AP+S A S + V P
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578
Query: 678 AKRTGILQEAKRRSTTKPMFTFKEPKVS-------PNPELLSLLQNSEGK--RGTGAGGD 728
A T LQ +R T P + P+++ P P S G G +
Sbjct: 579 ASPT--LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 636
Query: 729 SGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQ 788
S PEE ++ + + +P P + ++ P WS G AP
Sbjct: 637 STPEE------------LRGYDSGPEGGAAASPPPDAELAACHPA-----AWSRGPAP-- 677
Query: 789 PPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVST 848
P AF P P P +T GP G + + T P +T
Sbjct: 678 PLAFR---------------GAPGAPLPWPPAT----GP--GSADGLCTIYETEGPESAT 716
Query: 849 PTVNAVQPG-AVGPS-NELPGMSGRGAQLFAKRQSRM 883
P A+ PG + G S + +G GA + +Q+R+
Sbjct: 717 PAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 753
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 68.9 bits (167), Expect = 3e-11
Identities = 51/183 (27%), Positives = 82/183 (44%), Gaps = 40/183 (21%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++ T SL M ++R S+ E +Q +P + C
Sbjct: 66 AQNKIKGCTGSLNMTLQRASAAPKP--------------------EPVPVQ-KPTVTSVC 104
Query: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGP----------SYQRAPQMPDSQRGRV 178
+E T LAE QR G G K++ GP + P D+ + R+
Sbjct: 105 SE-------TSQELAEGQRRGSQ--GDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRL 155
Query: 179 AEE 181
E+
Sbjct: 156 IED 158
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 68.6 bits (166), Expect = 4e-11
Identities = 118/514 (22%), Positives = 179/514 (34%), Gaps = 68/514 (13%)
Query: 592 FPGSVNQPATPFSPTRNM----TSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAG--PAQ 645
F GS P SP +P +P S +TP FS +S +G P
Sbjct: 1502 FFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGY 1561
Query: 646 PPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVS 705
P W P P S + SS I S +S T E + P + P S
Sbjct: 1562 SPAW-SPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTP----QSPSYS 1616
Query: 706 PNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAV 765
P S + P S + N+ +S + T P +P
Sbjct: 1617 PTSPSYS---------------PTSP-----SYSPTSPNYSPTSPSYSPTSPSYSPTSPS 1656
Query: 766 KSSSSQPVTPVSPVW---SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTL 822
S +S +P SP + SP +PT P PTS PS S PSY P P+ +
Sbjct: 1657 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSP 1715
Query: 823 NVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSR 882
P + S +Y+P +PT + P + S P +
Sbjct: 1716 T------SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSY------- 1762
Query: 883 MEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQP 942
S T +++ + + TP+ P ++ +S +P +Y+P SPSY ++ + P
Sbjct: 1763 -------SPTSPSYSPTSPNYTPTSP-NYSPTSPSYSPTSPSYSPT-SPSYSPSSPRYTP 1813
Query: 943 SA-----AQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVN 997
+ + PS P + Y ++ +T P P+ S
Sbjct: 1814 QSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPK 1873
Query: 998 SALAMKQALPPRP-VNAASPTNVQASSVY--SVPAYTSPPSFFAEASSPVSASPVPVGIP 1054
+ P P + SPT S VY + P Y SP S +SP + P P
Sbjct: 1874 YSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKY-SPTSPTYSPTSPKYSPTSPTYSP 1932
Query: 1055 TSPKQE--SASSSYFVAPRPKFSAKKSGVTIQES 1086
TSPK S +S + P +S ++ +S
Sbjct: 1933 TSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDS 1966
Score = 62.4 bits (150), Expect = 3e-09
Identities = 93/388 (23%), Positives = 138/388 (35%), Gaps = 34/388 (8%)
Query: 758 PVAPKPA-VKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA 816
P P P S S P +P SPG Q P++ ++PS S P+Y P
Sbjct: 1580 PYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPT 1639
Query: 817 RPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLF 876
P+ + P + S +Y+P +PT + P + S P S
Sbjct: 1640 SPSYSPT------SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY- 1692
Query: 877 AKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLA 936
S T +++ + S +P+ P S+ +S +P +Y+P SPSY
Sbjct: 1693 -------------SPTSPSYSPTSPSYSPTSP-SYSPTSPSYSPTSPSYSPT-SPSYSPT 1737
Query: 937 ALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKV 996
+ P++ P+ P + Y + +T P+ P S
Sbjct: 1738 SPSYSPTS--PNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSP 1795
Query: 997 NSALAMKQALPPRP-VNAASPTNVQASSVY--SVPAYTSPPSFFAEASSPVSASPVPVGI 1053
+ + P P SPT +S Y S P+Y SP S +SP + P
Sbjct: 1796 SYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSY-SPTSPKYTPTSPSYSPSSPEYT 1854
Query: 1054 PTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYS 1113
PTSPK S Y PK+S + S + P S P+ T P YS
Sbjct: 1855 PTSPKYSPTSPKY-SPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPT---SPKYS 1910
Query: 1114 YSSKPTDGLEKANKRPTPWEAAAKSPLG 1141
+S PT PT + SP G
Sbjct: 1911 PTS-PTYSPTSPKYSPTSPTYSPTSPKG 1937
Score = 50.4 bits (119), Expect = 1e-05
Identities = 76/321 (23%), Positives = 115/321 (35%), Gaps = 48/321 (14%)
Query: 548 SSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTR 607
S S SY S + P +S TS + + P + + P S + + +SPT
Sbjct: 1679 SPTSPSYSPTSPS--YSPTSPSYSPTSPSYS-----PTSPSYSPTSPSYSPTSPSYSPTS 1731
Query: 608 NMTSPIADF--PAPPPYSAVTP--PPDAFSRGVSSPIAGPAQP---PPWPQPAPWSQPAF 660
SP + P P YS +P P + S +SP P P P P +P S P++
Sbjct: 1732 PSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTS-PSY 1790
Query: 661 YDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGK 720
+S + S + R ++ + + P ++ P SP + S
Sbjct: 1791 SPTSPSYSPTSPSYSPSSPR--YTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSP 1848
Query: 721 RGTGAGGDSGPEEDYLS--LGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSP 778
S PE S + + +S T P +P S +S +P SP
Sbjct: 1849 --------SSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSP 1900
Query: 779 VW---SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAV 835
V+ SP +PT P PTS T P+Y P P KG +
Sbjct: 1901 VYTPTSPKYSPTSPTYSPTSPKYSPT--------SPTYSPTSP----------KGSTYSP 1942
Query: 836 ASQNYTPKPTVSTPTVNAVQP 856
S Y+P + T A+ P
Sbjct: 1943 TSPGYSPTSPTYSLTSPAISP 1963
Score = 40.4 bits (93), Expect = 0.011
Identities = 81/327 (24%), Positives = 114/327 (34%), Gaps = 26/327 (7%)
Query: 900 AQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPL 959
A SPTP P S SS P A +P +SP+ P A +P G G P
Sbjct: 1564 AWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSP---------AYEPRSPG---GYTPQ 1611
Query: 960 NALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRP-VNAASPTN 1018
+ Y + ++ P+ P S + + P P + SP+
Sbjct: 1612 SPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1671
Query: 1019 VQASSVYS--VPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSA 1076
S YS P+Y SP S +SP + P PTSP S SY P +S
Sbjct: 1672 SPTSPSYSPTSPSY-SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY-SPTSPSYSP 1729
Query: 1077 KKSGVTIQESGRSLSLPGRSVPPP--ISTSPWVYQPTY-SYS-SKPTDGLEKANKRPTPW 1132
+ S + P S P TSP Y PT SYS + P N PT
Sbjct: 1730 TSPSYSPTSPSYSPTSPNYSPTSPNYTPTSP-SYSPTSPSYSPTSPNYTPTSPNYSPTSP 1788
Query: 1133 EAAAKSP-LGLVDDAFQPRNIQESIVANVVSAARRKVLPGPPEDWNERLSYIPQTQKAYM 1191
+ SP ++ P + + + + + + P P Y P T +Y
Sbjct: 1789 SYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTP-TSPSY- 1846
Query: 1192 GSCGRQEYNVTANNNMSTTSQYGSQLP 1218
S EY T+ T+ +Y P
Sbjct: 1847 -SPSSPEYTPTSPKYSPTSPKYSPTSP 1872
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 68.6 bits (166), Expect = 4e-11
Identities = 145/591 (24%), Positives = 202/591 (34%), Gaps = 137/591 (23%)
Query: 542 ESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPAT 601
ES S+ S S + + GHV Q+ S A +R + ++K S+N+P T
Sbjct: 545 ESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEA-WKRGTQLEESSKARMESMNRPYT 603
Query: 602 ----PFSPTRNMTSPI-ADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWS 656
P SP + +P A P+PP PPP P PPP P P P
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPP-----LPPP-------------PPPPPPPPPPPPPP 645
Query: 657 QPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQN 716
P +P+ Q A + PMF ++ LQN
Sbjct: 646 PP----------------PLPS------QSAPSAGSAAPMFV--------KYSTITRLQN 675
Query: 717 SEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQK---------TPPPVAPKPAVKS 767
+ G + P MQS S K + PPP P P
Sbjct: 676 ASQHSGALFKPPTPP-------------VMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG 722
Query: 768 SSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSI-KIAQPSYPPARPASTLNVAG 826
S+ + P AP+ P P K V I ++A P+ PP P +
Sbjct: 723 SAMAQLKPAP------CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP-----IPA 771
Query: 827 PFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKY 886
P PQA P PT ST TV V A P+ P + K+ + Y
Sbjct: 772 PLP-PQAPPKPLVTIPAPT-STKTVAPVVTQAAPPTPTPPVPPAK------KQPAFPASY 823
Query: 887 VVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLA---------- 936
+ S P P+LP K S PPP +P+ S +A
Sbjct: 824 IPPSPPTPP----VPVPPPTLP---KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 937 ALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKV 996
A++SQP P+ + + P K QP + F PP P+ S V
Sbjct: 877 AMESQPLKPVPANVAP---QSPPAVKAKPKWQPSSIPVPSPDFPPPP-----PESSLVFP 928
Query: 997 NSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTS 1056
+ A PP P ASPT ++ SP ++ SSP P P +
Sbjct: 929 PPPPSPVPAPPPPPPPTASPTPDKSG---------SPGKKTSKTSSPGGKKP-----PPT 974
Query: 1057 PKQESA--SSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSP 1105
P++ S+ SSS P PK + S V+ P + PP + P
Sbjct: 975 PQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025
Score = 63.9 bits (154), Expect = 9e-10
Identities = 119/528 (22%), Positives = 169/528 (32%), Gaps = 66/528 (12%)
Query: 574 SETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFS 633
S++ Q +VP N P P P TP S + P P+ P +SA PP
Sbjct: 694 SQSVKPQILVPPNGVVPP-PPPPPPPPTPGSAMAQL-KPAPCAPSLPQFSAPPPPLKIHQ 751
Query: 634 RGVSSPIAGPAQPPPWPQPAPWSQPAF--------YDSSERIASRDERISVPAKRTGILQ 685
+ +A P PPP P PAP A +S + + + P T +
Sbjct: 752 VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVP 811
Query: 686 EAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNF 745
AK++ + P P P L + P LS
Sbjct: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK-------PPPSPLSPVPSVVKQ 864
Query: 746 MQSSSAKQKTPP-----PVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG 800
+ S TPP P+ P PA + S P P W P
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQP------------------ 906
Query: 801 TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVG 860
SSI + P +PP P S+L P P + V + P PT S + PG
Sbjct: 907 ---SSIPVPSPDFPPPPPESSLVFPPP---PPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960
Query: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAP 920
PG G+ +R S + S + H + SL + + + +P
Sbjct: 961 SKTSSPG--GKKPPPTPQRNSS-----IKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Query: 921 PPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPL---NALDVMKHQPYQLNASLF 977
P +P P S + + G K P+ D + P + S F
Sbjct: 1014 SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDF 1073
Query: 978 TFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPS-- 1035
PP+ + LP V S P V P SV P T P
Sbjct: 1074 PPPPPETELPLPPIEIPAVFSG----NTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRND 1129
Query: 1036 ----FFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKS 1079
AE S + + V +PTSPK + F+A + +KS
Sbjct: 1130 STRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKS 1177
Score = 56.2 bits (134), Expect = 2e-07
Identities = 88/390 (22%), Positives = 129/390 (33%), Gaps = 38/390 (9%)
Query: 757 PPVAPKPAV-----KSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQP 811
PP++P+P + S S P+ P P P P PP P + S + S+ +
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Query: 812 SYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGR 871
R + +G P Q+ + KP + P V P P PG S
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG-SAM 725
Query: 872 GAQLFAKRQSRMEKYVVDSDTVQ----AHAARAQSPTPSLPASWKYSSNVRAPPPVAYNP 927
A + ++ ++ H + PTP P PP A P
Sbjct: 726 AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP-----------PPIPAPLP 774
Query: 928 IHSPSYPLAALKSQPSAAQPSKMGKKKG-KKPLNALDVMKHQPYQLNASLFTFQPPDAKD 986
+P PL + + S + + + P + K QP AS PP
Sbjct: 775 PQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQP-AFPASYIPPSPPTPPV 833
Query: 987 GLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSA 1046
+P + K S A PP P++ Q +S + P +PP+ ++ PV A
Sbjct: 834 PVPPPTLPKQQSFCAKP---PPSPLSPVPSVVKQIASQFPPP--PTPPAMESQPLKPVPA 888
Query: 1047 SPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRS-VPPPISTSP 1105
+ P P + S P P F ES P S VP P P
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP-----PESSLVFPPPPPSPVPAPPPPPP 943
Query: 1106 WVYQPTYSYSSKPTDGLEKAN----KRPTP 1131
PT S P K + K+P P
Sbjct: 944 PTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 65.5 bits (158), Expect = 3e-10
Identities = 161/698 (23%), Positives = 262/698 (37%), Gaps = 84/698 (12%)
Query: 482 EMLPDTTGKGALMFAKRRERMDQI----TAQKEEDKVG--GTPSREQDAAQTDGLRTTTS 535
E D TG+ L K+ Q+ T ++E DK G +P R++++ + + + T+
Sbjct: 841 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVE-IETSEE 899
Query: 536 YQRKEEESVRTQSSVSKSYI-EVSHGLGHVPQQNGFSGTSETANIQRMVPM------NRT 588
Q K+ V+ Q+ SK++ EV + + + A ++ VP +
Sbjct: 900 IQEKQ---VQKQTLPSKAFEREVERPVAN--------RECDPAELEEKVPKVILERDTQR 948
Query: 589 AKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPA-QPP 647
+P GS +Q SPT D P P ++ P + S G SP++ Q
Sbjct: 949 GEPEGGSQDQKGQASSPTPEPGVGAGDLPGP---TSAPVPSGSQSGGRGSPVSPRRHQKG 1005
Query: 648 PWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPN 707
P ++ A + SR ++ S A + EA KP+ + + ++P
Sbjct: 1006 LLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPA-PPQKPLNSQSQKHLAPP 1064
Query: 708 PELLSLLQNSEGK-RGTGAGGDSGPEEDYLSLGAEACN---FMQSSSAKQKTPPPV---A 760
P L LL + + R T G E LS E + +++ + + TP P A
Sbjct: 1065 PLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAA 1124
Query: 761 PKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPAS 820
P+P +S++QPVTP P + T + T P VV + QPS +P +
Sbjct: 1125 PEPHPSTSTAQPVTP-KPTSQATRSRTNRSSVKTPEP----VVPTAPELQPSTSTDQPVT 1179
Query: 821 TLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQ 880
+ + +G + S++ P PT +QP S + P S +Q R+
Sbjct: 1180 SEPTSQVTRGRK----SRSSVKTPETVVPTALELQPST---STDRPVTSEPTSQATRGRK 1232
Query: 881 SRM-----EKYVVDSDTVQAHAARAQ----SPTPSLPASWKYSSNVRAPPPVA-----YN 926
+R E V + +Q + Q PT K S+V+ P PV
Sbjct: 1233 NRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELR 1292
Query: 927 PIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKD 986
P S P+ + + + M K + V+ P +L S T QP
Sbjct: 1293 PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPE-----TVVPTAP-ELQISTSTDQPV---- 1342
Query: 987 GLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSA 1046
P+ +S S M P +P + S+ P P S S+
Sbjct: 1343 -TPKPTSRTTRSRTNMSSVKNPESTVPIAP-ELPPSTSTEQPVTPEPTSRATRGRKNRSS 1400
Query: 1047 SPVP-VGIPTSPKQE-SASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVP--PPIS 1102
P +PT+PK E S S+ V P P A + + + S+ P VP P +
Sbjct: 1401 GKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRG----RTNRSSVKTPETVVPTAPELQ 1456
Query: 1103 TSPWVYQP-TYSYSSKPTDGLEKANKRPTPWEAAAKSP 1139
S QP T +S+ T G + TP +P
Sbjct: 1457 PSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAP 1494
Score = 45.1 bits (105), Expect = 4e-04
Identities = 116/595 (19%), Positives = 200/595 (33%), Gaps = 82/595 (13%)
Query: 518 PSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETA 577
PS D T + + RK SV+T +V + +E+ TSE
Sbjct: 1170 PSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTS-----TDRPVTSEPT 1224
Query: 578 NIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVS 637
+ NR++ P V A P+ + P+ + P Y A + S
Sbjct: 1225 SQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVT---SEPTYQATRGRKNRSSVKTP 1281
Query: 638 SPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRR---STTK 694
P+ P P P + +S SR SV T + + + ST +
Sbjct: 1282 EPVV-PTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQ 1340
Query: 695 PMFTFKEPKVSPNPELLSLLQNSEGKRGTG-----AGGDSGPEEDYLSLGAEACNFMQSS 749
P+ + + + +S ++N E + P + A +SS
Sbjct: 1341 PVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSS 1400
Query: 750 SAKQKTPPPVAPKPAVKSSSSQPVT------------------------PVSPVWSPGVA 785
+T P APK +S+ QPVT P +P P +
Sbjct: 1401 GKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTS 1460
Query: 786 PTQP-PAFPTSNPSKG-TVVSSIKIAQ---PSYPPARPASTLN---VAGPFKGPQAAVAS 837
QP PTS ++G T SS+K + P+ P + +++ + + P +
Sbjct: 1461 TDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKN 1520
Query: 838 QNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQS--RMEKYVVDSDTVQA 895
++ P P +QP P + R + R S E V + +Q
Sbjct: 1521 RSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQP 1580
Query: 896 HAARAQ----SPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMG 951
+R Q PT S+V+ P PV P+ P + K+
Sbjct: 1581 STSRNQLVTPEPTSRATRCRTNRSSVKTPEPVV------PTAPEPHPTTSTDQPVTPKLT 1634
Query: 952 KKKGKKPLNALDVMKHQPYQLNAS-LFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRP 1010
+ ++ N V +P + AS L F P D + P
Sbjct: 1635 SRATRRKTNRSSVKTPKPVEPAASDLEPFTPTD-------------------QSVTPEAI 1675
Query: 1011 VNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSS 1065
+++S+V ++P T+ P F + ++ SP P+ P+ K++ A+ +
Sbjct: 1676 AQGGQSKTLRSSTVRAMPVPTT-PEFQSPVTTDQPISPEPITQPSCIKRQRAAGN 1729
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 65.5 bits (158), Expect = 3e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 30/160 (18%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++ T SL M ++R S+ E +Q +P + C
Sbjct: 66 AQNKIKGCTGSLNMTLQRASAAPKP--------------------EPVPVQ-KPTVTSVC 104
Query: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAP 168
+E T LAE QR G G K++ G + P
Sbjct: 105 SE-------TSQELAEGQRRGSQ--GDSKQQNGKIPPKRP 135
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 64.7 bits (156), Expect = 5e-10
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++S + +L + +++ I + + L + H Q PA T
Sbjct: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPH---------QKDPALDTNG 115
Query: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKV 188
+ +P + R+ P G+ E P++ A P +
Sbjct: 116 SLVAPSP-------SPEARASPGTPGT--PELRPTFSPAFSRPSA----------FSSLA 156
Query: 189 EAVQPGPV-VELQLSLSQERHKGASGPLVALPGAEKSK 225
EA PGP L+ S E + GP ALPG+ + +
Sbjct: 157 EASDPGPPRASLRAKTSPEGARDLLGP-KALPGSSQPR 193
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 64.7 bits (156), Expect = 5e-10
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
Query: 69 VIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQC 128
++S + +L + +++ I + + L + H Q PA T
Sbjct: 65 AQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPH---------QKDPALDTNG 115
Query: 129 TEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKV 188
+ +P + R+ P G+ E P++ A P +
Sbjct: 116 SLVAPSP-------SPEARASPGTPGT--PELRPTFSPAFSRPSA----------FSSLA 156
Query: 189 EAVQPGPV-VELQLSLSQERHKGASGPLVALPGAEKSK 225
EA PGP L+ S E + GP ALPG+ + +
Sbjct: 157 EASDPGPPRASLRAKTSPEGARDLLGP-KALPGSSQPR 193
Score = 47.0 bits (110), Expect = 1e-04
Identities = 103/436 (23%), Positives = 150/436 (34%), Gaps = 55/436 (12%)
Query: 754 KTPPPVAPK---PAVKSSSSQPVTPVSPVW--SPGVAPTQPPAFPTSNP--SKGTVVSSI 806
+TP PV P PA+ ++ S SP SPG P P PT +P S+ + SS+
Sbjct: 97 QTPLPVIPHQKDPALDTNGSLVAPSPSPEARASPGT-PGTPELRPTFSPAFSRPSAFSSL 155
Query: 807 KIAQPSYPP-------ARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQ---- 855
A PP P ++ GP P ++ Q P S T+ +
Sbjct: 156 AEASDPGPPRASLRAKTSPEGARDLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQ 215
Query: 856 ------------PGAVGPSNELPGMSGRGA-QLFAKRQSRMEKYVVDSDTVQAHAARAQS 902
PG P +L S Q K Q++ E ++D ++ QS
Sbjct: 216 MSLRGKASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPED---EADEWARRSSNLQS 272
Query: 903 PTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQ------PSAAQPSKMGKKKGK 956
+ + A + ++ P A +P SQ P++AQP
Sbjct: 273 RSFRILAQMTGTEFMQDPDEEALRRSSTPIEHAPVCTSQATTPLLPASAQPPAAASPSAA 332
Query: 957 KPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSS----VKVNSALAMKQALPPRPVN 1012
P A + + P D+ PQ SS V +SA A + P
Sbjct: 333 SPPLATAAAHTAIASASTTAPASSPADSPR--PQASSYSPAVAASSAPATHTSYSEGPAA 390
Query: 1013 AASPTNVQAS-----SVYS-VPAYTSPPSFFAEAS-SPVSASPVPVGIPTSPKQESASSS 1065
A V + SVY VPA T PS A S +P + SP P P+ + S
Sbjct: 391 PAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPV 450
Query: 1066 YFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKA 1125
P P + S S++ G P S PWV ++S P
Sbjct: 451 PTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPA-SRPPWVTDDSFSQKFAPGKSTTSI 509
Query: 1126 NKRPTPWEAAAKSPLG 1141
+K+ P A +P G
Sbjct: 510 SKQTLPRGGPAYTPAG 525
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 584 PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADF-PAPPPYSAVTPPPD---AFSRGVSSP 639
P T P P PA ++P SP+ + P+P P +P P+ A S S
Sbjct: 426 PTPYTPSPAPAYTPSPAPAYTP-----SPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG 480
Query: 640 IAGPAQPPPWPQPAPWSQ 657
A PA PPW +SQ
Sbjct: 481 PAEPASRPPWVTDDSFSQ 498
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/81 (38%), Positives = 51/81 (62%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSS 89
++ T SL M ++R S+
Sbjct: 66 AQNKIKGCTGSLNMTLQRASA 86
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/81 (38%), Positives = 51/81 (62%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+S+ G APWGFRLQGGK+ PL ++ +++ KA+ + + GD V+SI+G +T+ E
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLE 65
Query: 69 VIKLMESITDSLQMLIKRPSS 89
++ T SL M ++R S+
Sbjct: 66 AQNKIKGCTGSLNMTLQRASA 86
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 64.3 bits (155), Expect = 7e-10
Identities = 112/409 (27%), Positives = 150/409 (36%), Gaps = 73/409 (17%)
Query: 746 MQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAF------PTSNPSK 799
+Q+ Q TPP PA+ SS P+ SP P +P+ PP+ P + PS+
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP--SPSAPPSLQTLPSPPATPPSQ 325
Query: 800 GTVV--SSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPG 857
T S A S+ P+ P S L P P A+ P P S P P
Sbjct: 326 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385
Query: 858 AVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNV 917
P+ A + S VQA SP S P S +
Sbjct: 386 PQAPN------------ALAVHLLQAPFSPPPSPPVQAPF----SPPASPPVSPSATPPS 429
Query: 918 RAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLF 977
+APP +A P+ P P A+ PSA P + PL A + +P
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPP-----PQAPPPLAAPPLQLAKP-------- 476
Query: 978 TFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVN--AASPTNVQASSVYSVPAYTSPPS 1035
PP A L A QALP P + +P + AS S P T PP
Sbjct: 477 ---PPQAPPAL----------ATPPLQALPSPPASFPGQAPFSPSASLPMS-PLATPPPQ 522
Query: 1036 FFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSL--- 1092
+ PV A+P+ + +P SP AS + RP + V SG L+L
Sbjct: 523 -----APPVLAAPL-LQVPPSP---PASPTLQAPRRPPTPGPDTSV----SGPRLTLALA 569
Query: 1093 PGRSVPPPISTSPWVYQPTYS-YSSKPTDGLEKANKRPT-PWEAAAKSP 1139
PG PP S S + P + +SS T E+ + P AA SP
Sbjct: 570 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 618
Score = 57.0 bits (136), Expect = 1e-07
Identities = 110/493 (22%), Positives = 166/493 (33%), Gaps = 48/493 (9%)
Query: 486 DTTGKGALMFAKRRERMDQITAQKEEDKVGGTPS----REQDAAQTD-GLRTTTSYQRKE 540
+T +G A +R + + GTPS R AA T+ GL R
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 541 EESVRTQSSVSK----SYIEVSHGLGHVPQQNGFSGTSETANIQRMV-PMNRTAKPFPGS 595
+ + SVS S E S P G + ++ P++ A+ P +
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 596 VNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPW 655
P P P++ P P A+ PP R ++P GP P P+P
Sbjct: 251 RGTPRAPAHPSQ---------PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 656 SQPAFYDSSERIASRDERISVPAKRTGILQEAKRRST-----TKPMFTFKEPKVSPNPEL 710
+ P+ + P++ T L ++T + P+ P P L
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361
Query: 711 LSLLQNSEGKRGTGAGGDSGP--EEDYLSLGAEACNFMQSSSAKQKTPPPVAP-----KP 763
L + A P + A A + +Q+ + +PP AP P
Sbjct: 362 --ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 764 AVKSSSSQP-VTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTL 822
V S++ P P S P P PPA P +PS P PP A L
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS--------ATPPPQAPPPLAAPPL 471
Query: 823 NVA--GPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQ 880
+A P P A P P S P P A P + L + + A
Sbjct: 472 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 531
Query: 881 SRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRA---PPPVAYNPIHSPSYPLAA 937
++ S T+QA R +P P S + A PPP + +P + S P A
Sbjct: 532 LQVPPSPPASPTLQA-PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 590
Query: 938 LKSQPSAAQPSKM 950
S + + P ++
Sbjct: 591 GHSSSATSTPEEL 603
Score = 52.8 bits (125), Expect = 2e-06
Identities = 95/395 (24%), Positives = 133/395 (33%), Gaps = 59/395 (14%)
Query: 599 PATPFSP-TRNMTSPIAD-----FPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQP 652
PATP S T ++ SP P+PP TPPP A P+ P PP P
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378
Query: 653 APWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLS 712
+P + P+ + A +LQ + P+ P SP P S
Sbjct: 379 SPLATPSPQAPN-------------ALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPS 424
Query: 713 LLQNSEGKRGTGAG----GDSGPEEDYLSLGA----EACNFMQSSSAKQKTPPPVAPKPA 764
S+ A S P +S A +A + + + PPP AP PA
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PA 483
Query: 765 VKSSSSQPVTPVSPVWSPGVAPTQPPA------FPTSNPSKGTVVSSIKIAQPSYPPARP 818
+ + Q + P P PG AP P A T P V+++ + P PPA P
Sbjct: 484 LATPPLQAL-PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 542
Query: 819 ASTLNVAGPFKGPQAAVASQNYT--------------PKPTVSTPTVNAVQPGAVGPSNE 864
P GP +V+ T P T+S P + A E
Sbjct: 543 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 602
Query: 865 LPGM-SGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPV 923
L G SG A D++ H A A S P+ P +++ + P P
Sbjct: 603 LRGYDSGPEGGAAASPPP-------DAELAACHPA-AWSRGPAPPLAFRGAPGAPLPWPP 654
Query: 924 AYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKP 958
A P + P +A P+ G P
Sbjct: 655 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 37.4 bits (85), Expect = 0.091
Identities = 79/337 (23%), Positives = 116/337 (34%), Gaps = 71/337 (21%)
Query: 574 SETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAP---PPYSAVTPPPD 630
S +A P + A P + PA+P P +P P P PP PPP
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 631 AFSRGVSSPI-AGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISV------------P 677
A + P+ A P+ P +P AP+S A S + V P
Sbjct: 480 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539
Query: 678 AKRTGILQEAKRRSTTKPMFTFKEPKVS-------PNPELLSLLQNSEGK--RGTGAGGD 728
A T LQ +R T P + P+++ P P S G G +
Sbjct: 540 ASPT--LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597
Query: 729 SGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQ 788
S PEE ++ + + +P P + ++ P WS G AP
Sbjct: 598 STPEE------------LRGYDSGPEGGAAASPPPDAELAACHPA-----AWSRGPAP-- 638
Query: 789 PPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVST 848
P AF P P P +T GP G + + T P +T
Sbjct: 639 PLAFR---------------GAPGAPLPWPPAT----GP--GSADGLCTIYETEGPESAT 677
Query: 849 PTVNAVQPG-AVGPS-NELPGMSGRGAQLFAKRQSRM 883
P A+ PG + G S + +G GA + +Q+R+
Sbjct: 678 PAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 714
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 64.3 bits (155), Expect = 7e-10
Identities = 142/607 (23%), Positives = 213/607 (35%), Gaps = 119/607 (19%)
Query: 588 TAKPFPGSVNQPATPFSPT--------RNMTSPI-ADFPAPPPYSAVTPPPDAFSRGVSS 638
T+ P G+ +TP S T T+P+ ++ P A +PPP A G S
Sbjct: 975 TSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTA--EGTSM 1032
Query: 639 PIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFT 698
P + P++ P S S S + PA T+ P+ T
Sbjct: 1033 PTSTPSEGSTPLTRMPVSTTMVASSETSTLS-----TTPA------------DTSTPVTT 1075
Query: 699 FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPP 758
+ + S T A G S P Y S + T P
Sbjct: 1076 YSQASSS----------------STTADGTSMPTSTY------------SEGSTPLTSVP 1107
Query: 759 VAPKPAVKSSSSQ----PVTPVSPVWSPGVAPTQPP-----AFPTSNPSKGTVVSSIKIA 809
V+ + V S +S PV PV + A + P + PTS PS+GT +
Sbjct: 1108 VSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV 1167
Query: 810 QPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMS 869
+ + A+TL+ Q A +++ +P PT ++ PG S L M
Sbjct: 1168 STTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGE--RSTPLTSMP 1225
Query: 870 GRGAQLFAKRQSRMEKYVVDSDT-VQAHAARAQSPT----PSLPAS-WKYSSNVRAPPPV 923
R + + S + VD+ T V A + SPT SLP S S + PV
Sbjct: 1226 VRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPV 1285
Query: 924 AYNPIHSPSY------------PLAA---LKSQPSAAQPSKMGK---KKGKKPLNALDVM 965
+ + SP P+ + S P+ A+ + M +G+ PL ++ V
Sbjct: 1286 STTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVN 1345
Query: 966 KHQPYQLNASLFTFQPPDAKDGLPQK----SSVKVNSALAMKQALPPR--------PVNA 1013
S+ + P D + SS + +M + P PV+
Sbjct: 1346 TTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVST 1405
Query: 1014 ASPTNVQASSVYSVPAYTSPP-SFFAEA-SSPVSASPVPVGIPTSPKQESASSSYFVAPR 1071
+ +AS++ + P TS P + AEA SSP +A + IPTS E +
Sbjct: 1406 TPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAE--GISIPTSTPSEGKT-------- 1455
Query: 1072 PKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTP 1131
P S S + S S S P S SP V S S P +G A P+
Sbjct: 1456 PLKSIPVSNTPVANSEAST----LSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSE 1511
Query: 1132 WEAAAKS 1138
A S
Sbjct: 1512 GSTALTS 1518
Score = 59.7 bits (143), Expect = 2e-08
Identities = 126/609 (20%), Positives = 208/609 (34%), Gaps = 86/609 (14%)
Query: 546 TQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSP 605
T S+ + S + G G +P S SE + +P++ T P + TP
Sbjct: 3019 TTSTEASSSPTTAEGTG-IP----ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDS 3073
Query: 606 TRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAG-PAQPPPWPQPAPWSQPAF-YDS 663
+ + +P P + P +S G S+P+ G P P A + D+
Sbjct: 3074 NSPVVTSTEVSSSPTPAEGTSMPISTYSEG-STPLTGVPVSTTPVTSSAISTLSTTPVDT 3132
Query: 664 SERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGT 723
S + + E S P G S T+ P L+ +SE +
Sbjct: 3133 STPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYM-------PVSTMLVVSSEDSTLS 3185
Query: 724 GAGGDSGPE-----EDYLSLGAEACNFMQSSSAKQKTP---PPVAPKPAVKSSSS----Q 771
D+ E S AE + S+ ++ TP PV+ P S +S
Sbjct: 3186 ATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTT 3245
Query: 772 PVTPVSPVWSPGVAPTQPP-----AFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAG 826
PV +P+ + A + PP + PTS PS+G+ + + P ST VA
Sbjct: 3246 PVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLT----------SMPVSTTTVAS 3295
Query: 827 PFKGPQAAVASQNYTPKPTVSTPTVNA-VQPGAVGP-------SNELPGMSGRGAQLFAK 878
+ + TP T S + + + G P S L MS + +
Sbjct: 3296 SETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSS 3355
Query: 879 RQSRMEKYVVDSDTVQAHAARAQ-SPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAA 937
S + VD+ T + A SPT + S P SPS
Sbjct: 3356 EASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSI---------------PTSSPSEGTTP 3400
Query: 938 LKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVN 997
L S P + P + ++ + P N + T + + + +S+ +
Sbjct: 3401 LASMPVSTTPVVSSE---------VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTS 3451
Query: 998 SALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSP 1057
+ L P++ + +AS++ + P TS P SSP ++SP + + P
Sbjct: 3452 TTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTP---VTTSSPTNSSPTTAEVTSMP 3508
Query: 1058 KQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRS-----VPPPISTSPWVYQPTY 1112
+ S P + V E+ + P S S+SP Q T
Sbjct: 3509 TSTAGEGS---TPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTT 3565
Query: 1113 SYSSKPTDG 1121
S P++G
Sbjct: 3566 MRMSTPSEG 3574
Score = 57.8 bits (138), Expect = 7e-08
Identities = 97/480 (20%), Positives = 173/480 (36%), Gaps = 87/480 (18%)
Query: 740 AEACNFMQSSSAKQKTP---PPVAPKPAVKSSSS----QPVTPVSPVWSPGVAPTQPP-- 790
AE + S+ ++ TP PV P S +S PV +PV + + P
Sbjct: 1204 AEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTA 1263
Query: 791 ---AFPTSNPSKG-TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTV 846
+ PTS S+G T+++SI ++ ++ L KGP + +P P
Sbjct: 1264 EGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAE 1323
Query: 847 STPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDT-VQAHAARAQSPTP 905
T + P +P + A + S + VD+ T V SPT
Sbjct: 1324 GTSMPTSTYSEGRTPLTSIPVNTTLVA---SSAISILSTTPVDNSTPVTTSTEACSSPTT 1380
Query: 906 SLPASWKYSSNVRAPPPVAYNPIHS--------------------PSYPLAALKSQPSAA 945
S S S+ P+ P+ + P A S P+ A
Sbjct: 1381 SEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTA 1440
Query: 946 QPSKMGKK---KGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGL------------PQ 990
+ + +GK PL ++ V AS + P D+ + +
Sbjct: 1441 EGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE 1500
Query: 991 KSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPP---------------- 1034
+S+ +++ AL PV+ + + + +S+ + PA TS P
Sbjct: 1501 GTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADG 1560
Query: 1035 -----SFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAK---KSGVTIQES 1086
S ++E S+P+++ PV + S + + S++ + + + +A S T + S
Sbjct: 1561 TSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTP-IDSKTQVTASTEASSSTTAEGS 1619
Query: 1087 GRSLSLPGRSVP----PPISTSPWVYQPTYSYSSKPTDG------LEKANKRPTPWEAAA 1136
++S P P P+ST+P + S+ P D + + PTP E +
Sbjct: 1620 SMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTS 1679
Score = 54.7 bits (130), Expect = 6e-07
Identities = 148/688 (21%), Positives = 231/688 (33%), Gaps = 105/688 (15%)
Query: 527 TDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMN 586
T ++S E S+ T + S S + H P + +GT T + P+
Sbjct: 2783 TTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVT 2842
Query: 587 RTAK-----------------PFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPP 629
+ K GS + P S T +S + P +++ P
Sbjct: 2843 TSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSI--PV 2900
Query: 630 DAFSRGVSSPIAGPAQPPPWPQPAPWSQPAF---------------------YDSSERIA 668
+ G SSP P P+ S P D+ +
Sbjct: 2901 TTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVT 2960
Query: 669 SRDERISVPAKRTG----ILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTG 724
+ E S P G I +RR+ M P S L S T
Sbjct: 2961 TSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTL-----SRTPADTS 3015
Query: 725 AGGDSGPEEDYLSLGAEACNFMQSSSAKQKTP---PPVAPKP-AVKSSSSQPVTPVSPVW 780
+ E AE S+ ++ TP PV+ P A+ +S+ TPV
Sbjct: 3016 TPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSN- 3074
Query: 781 SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYP-PARPASTLNVAGPFKGPQAAVASQN 839
SP V T+ + PT P++GT + ++ S P P ST V +A+++ +
Sbjct: 3075 SPVVTSTEVSSSPT--PAEGTSMPISTYSEGSTPLTGVPVSTTPVT------SSAISTLS 3126
Query: 840 YTPKPTVSTPTVNAVQPGAVGPSNELPGM-----SGRGAQLFAKRQSRMEKYVVDSDTVQ 894
TP T STP + + + ++E M S L S M VV S+
Sbjct: 3127 TTPVDT-STPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTM--LVVSSEDST 3183
Query: 895 AHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKK 954
A + TP ++ SS + P +PS + L S P + P +
Sbjct: 3184 LSATPVDTSTPVTTSTEATSSTTAEGTSI---PTSTPSEGMTPLTSVPVSNTPVASSEAS 3240
Query: 955 --------GKKPL-NALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQA 1005
PL + + P S+ T P + L A +
Sbjct: 3241 ILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETST 3300
Query: 1006 LPPRPVNAASP--TNVQASSVYSVPAYTS-PPSFFAEASSPVSASPVPVGIPTSPKQESA 1062
L P + ++P T QASS + TS P S ++E S+P++ + T+P S
Sbjct: 3301 LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLT----NMSFSTTPVVSSE 3356
Query: 1063 SSSYFVAP-------RPKFSAKKSGVTIQESGRSLSLPGRSVPP----PISTSPWVYQPT 1111
+S+ P A S T + + S P P P+ST+P V
Sbjct: 3357 ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEV 3416
Query: 1112 YSYSSKPTDGLEKANKRPTPWEAAAKSP 1139
+ S+ P D +N T A+ SP
Sbjct: 3417 NTLSTTPVD----SNTLVTTSTEASSSP 3440
Score = 50.1 bits (118), Expect = 1e-05
Identities = 143/681 (20%), Positives = 230/681 (33%), Gaps = 85/681 (12%)
Query: 571 SGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPD 630
S SE + + +P++ T P + TP +T+ +P P + P
Sbjct: 799 STPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTS 858
Query: 631 AFSRG----VSSP-----IAGPAQPPPWPQPAPWSQPAFYDSSERIA-SRDERISVPAKR 680
+S G S P +A A P S P + R + + E S+P
Sbjct: 859 TYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST 918
Query: 681 TG----------------ILQEAKRRS-----TTKPMFTFKEPKVSPNPELLSLLQNSEG 719
G + EA+ S T+ P+ T E SP + + S
Sbjct: 919 PGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP 978
Query: 720 KRGTGAGGDSGPEEDYLSLGAEA---------CNFMQSSSAKQKTPPPVAPKPAVKSSS- 769
GT S P L +EA N ++S + +PPP A ++ +S+
Sbjct: 979 SEGT-TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTP 1037
Query: 770 SQPVTPVS--PVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPA----RPASTLN 823
S+ TP++ PV + VA ++ T+ T V++ A S A P ST +
Sbjct: 1038 SEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYS 1097
Query: 824 VAG-PFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSR 882
P + + T+ST V+ P + G + S
Sbjct: 1098 EGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSE 1157
Query: 883 ----MEKYVVDSDTVQAHAARAQSPTP-SLPASWKYSSNVRAPPP---VAYNPIHSPSYP 934
+ V + V + A S TP S+ +PPP V P +P
Sbjct: 1158 GTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGER 1217
Query: 935 LAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSV 994
L S P P + L+ V P +A T P +G +S+
Sbjct: 1218 STPLTSMPVRHTPVASSE---ASTLSTSPVDTSTPVTTSAE--TSSSPTTAEG----TSL 1268
Query: 995 KVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIP 1054
++ L PV+ T+ +AS++ + P T P S+ VS+SP P
Sbjct: 1269 PTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGP---VVTSNEVSSSPTPAEGT 1325
Query: 1055 TSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSL---SLPGRSVPPPIST----SPWV 1107
+ P +S+Y P S + + S S+ + S P ST SP
Sbjct: 1326 SMP-----TSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTT 1380
Query: 1108 YQPTYSYSSKPTDGLEKANKRP---TPWEAAAKSPLGLVD-DAFQPRNIQESIVANVVSA 1163
+ T +S P++G P TP ++ S L D P ++ +A
Sbjct: 1381 SEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTA 1440
Query: 1164 ARRKVLPGPPEDWNERLSYIP 1184
+ P + L IP
Sbjct: 1441 EGISIPTSTPSEGKTPLKSIP 1461
Score = 43.9 bits (102), Expect = 0.001
Identities = 75/360 (20%), Positives = 138/360 (38%), Gaps = 44/360 (12%)
Query: 741 EACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVT----PV---SPVWSPGVAPTQP---- 789
E+ +S++++ TP P +K +SS+ +T PV +PV A + P
Sbjct: 202 ESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAE 261
Query: 790 -PAFPTSNPSKGT------------VVSSIKIAQPSYPPARP----ASTLNVAGPFKGPQ 832
P+ S PS G+ VVSS + P A ST + P
Sbjct: 262 GPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEG 321
Query: 833 AAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLF--AKRQSRMEKYVVDS 890
++ + YT T T T + P A + L + L + S + +
Sbjct: 322 TSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEAT 381
Query: 891 DTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALK--SQPSAAQPS 948
+ + + +P ++P S ++ A P+ S ++ A + S P+ A+ +
Sbjct: 382 SMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTI-PVDSKTFVTTASEASSSPTTAEDT 440
Query: 949 KMGKK---KGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQA 1005
+ +G PL ++ V AS + P D+K + + + A +
Sbjct: 441 SIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNS 500
Query: 1006 LPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSS 1065
+P + S T + + SV ++P +S +S +S +PV P + E++SSS
Sbjct: 501 MPTSTPSEGS-TPLTSMSVSTMPVASSE-------ASTLSTTPVDTSTPVTTSSEASSSS 552
Score = 42.7 bits (99), Expect = 0.002
Identities = 97/449 (21%), Positives = 160/449 (35%), Gaps = 70/449 (15%)
Query: 674 ISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQ-NSEGKRGTGAGGDSGPE 732
IS P++ + +L T+ P+ T P SP LS +S T S P
Sbjct: 2094 ISAPSEGSPLL-------TSIPLST--TPVASPEASTLSTTPVDSNSPVITSTEVSSSP- 2143
Query: 733 EDYLSLGAEACNFMQSSSAKQKTP-------PPVAPKPAVKSSSSQPVTPVSPVWSPGVA 785
+ E + S+ + ++TP V A+ + S+ PV +PV + A
Sbjct: 2144 -----IPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198
Query: 786 PTQPP-----AFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNY 840
+ P + PTS PS+G+ + ASTL+ A P S
Sbjct: 2199 RSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLS-ATPVDTSTPVTTSTEA 2257
Query: 841 TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARA 900
T PT + T + G + L + + S + VDS+T + A
Sbjct: 2258 TSSPTTAEGTSIPTSTLSEG-TTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEA 2316
Query: 901 QSPTPSLPA-SWKYSSNVRAPPPVAYNPIHSP---SYPLAALKSQPS-AAQPSKMGKKKG 955
SP P+ S S++ P+ P+ + S+ + L + P+ + P + G
Sbjct: 2317 SSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAG 2376
Query: 956 KKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAAS 1015
P A D + S ++ +G +SV PV+
Sbjct: 2377 SSPTTADDT------SMPTSTYS-------EGSTPLTSV---------------PVSTMP 2408
Query: 1016 PTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFS 1075
+ +AS+ + P TS P + +S + IPTSP E + P
Sbjct: 2409 VVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTT------PLASMP 2462
Query: 1076 AKKSGVTIQESGRSLSLPGRSVPPPISTS 1104
+ V E+G +LS P++TS
Sbjct: 2463 VSTTPVVSSEAG-TLSTTPVDTSTPMTTS 2490
Score = 41.6 bits (96), Expect = 0.005
Identities = 119/649 (18%), Positives = 220/649 (33%), Gaps = 121/649 (18%)
Query: 571 SGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPD 630
S TSE + ++P++ T + TP + +T+ +P + P
Sbjct: 3451 STTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTS 3510
Query: 631 AFSRGVSSPIAG-PAQPPPWPQP-------APWSQPAFYDSSERIASRDERISVPAKRTG 682
G S+P+ P P P F SS + +S + V R
Sbjct: 3511 TAGEG-STPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMS 3569
Query: 683 ILQEAKRRSTTKPMF-TFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDY---LSL 738
E TT + T+ + P S+ +++ T + P E +S
Sbjct: 3570 TPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMST 3629
Query: 739 GAEACNFMQ-----------SSSAKQKTPPPVAPKPAVKSS--SSQPVTP---VSPVWSP 782
+E + S + T P P + S+ SS PVTP P+W+P
Sbjct: 3630 PSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTP 3689
Query: 783 GVAPTQPPAFPTS----NPSKGTVVS--SIKIAQP--------SYPPARPASTLNVAGPF 828
T P S S+G+ +S S+ + P S ++T++V+ P
Sbjct: 3690 SEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPM 3749
Query: 829 K----GPQAAVASQNYTPKPTVSTPTVNAV---------QPGAVGPSNELPGMSGRGAQL 875
+ G V++ T P STP++ +V G+ P+ L G +
Sbjct: 3750 EISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTT-LEGTTTMPMST 3808
Query: 876 FAKRQSRMEKYVVDSDTVQAHAARAQSPTP------------------------------ 905
++R + + ++ +V + + + TP
Sbjct: 3809 TSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISI 3868
Query: 906 ---------------SLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKM 950
+LP S+ +++ + PP+ + +PS A+ + P A S
Sbjct: 3869 TSERSTPLTTLLVSTTLPTSFP-GASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVS 3927
Query: 951 GKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRP 1010
+G P + + A +F P + + + P
Sbjct: 3928 VITEGSTPGTTIFIPSTPVTSSTADVF-----------PATTGAVSTPVITSTELNTPST 3976
Query: 1011 VNAASPTNVQASSVYSVPAYT--SPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV 1068
++++ T+ + ++ PA T +P ++ +++P + G TS SA+S+
Sbjct: 3977 SSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATST--- 4033
Query: 1069 APRPKFSAKKSGVT-IQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSS 1116
P S VT ES R ++ ++PP + PT S SS
Sbjct: 4034 -PHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASS 4081
Score = 40.8 bits (94), Expect = 0.008
Identities = 128/674 (18%), Positives = 221/674 (32%), Gaps = 103/674 (15%)
Query: 486 DTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESVR 545
DT G + R T++ D PS +D + TT S
Sbjct: 101 DTPGVSSTRMTPTESRT---TSESTSDSTTLFPSSTEDTSSP-----TTPEGTDVPMSTP 152
Query: 546 TQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSP 605
++ S+S + VS +P ++ + ++ + + A P + P S
Sbjct: 153 SEESISSTMAFVS--TAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKST 210
Query: 606 TRNMTSPIADFPAPPPYSAVTPPPDAFSRGV--SSPIAGPAQPPPWPQPAPWSQPAFYDS 663
++P+ PA A + + V S+P+ AQ P A P+ +S
Sbjct: 211 NSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTA--EGPSLSNS 268
Query: 664 SERIASRDERISVPAKRTGILQEAKRRSTTK-----PMFTFKEPKVSPNPELLSLLQNSE 718
+ S + + EA STT P+ T E SP
Sbjct: 269 APSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSP------------ 316
Query: 719 GKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSP 778
T A G S P Y + S+ TP P A S+ +TPV
Sbjct: 317 ----TTAEGTSIPTSTYT----------EGSTPLTSTPASTMPV-ATSEMSTLSITPVDT 361
Query: 779 VWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPAR-PASTLNVAG---------PF 828
+ T+P + PT+ + + S++ ++ S P P ST+ VA P
Sbjct: 362 S-TLVTTSTEPSSLPTTAEATSMLTSTL--SEGSTPLTNMPVSTILVASSEASTTSTIPV 418
Query: 829 KGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVV 888
+ + PT + T A + G S L M + + S + V
Sbjct: 419 DSKTFVTTASEASSSPTTAEDTSIATSTPSEG-STPLTSMPVSTTPVASSEASNLSTTPV 477
Query: 889 DSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPS 948
DS T + A S P+ + +S + P P+ S S + + P A+ +
Sbjct: 478 DSKTQVTTSTEASSSPPTA----EVNSMPTSTPSEGSTPLTSMS-----VSTMPVASSEA 528
Query: 949 KMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPP 1008
+ P + + T + P+ +S+ ++ L
Sbjct: 529 S--------------TLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTN 574
Query: 1009 RPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV 1068
PV+ + +AS+ + PA ++ + TS + S+S++
Sbjct: 575 MPVSTRLVVSSEASTTSTTPADSN------------------TFVTTSSEASSSSTTAEG 616
Query: 1069 APRPKFSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKA--N 1126
P + + G TI S +L S +ST+P + S++ T A
Sbjct: 617 TSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGT 676
Query: 1127 KRPTPWEAAAKSPL 1140
PT +PL
Sbjct: 677 SMPTSTYTEGSTPL 690
Score = 39.3 bits (90), Expect = 0.024
Identities = 119/583 (20%), Positives = 204/583 (34%), Gaps = 102/583 (17%)
Query: 591 PFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWP 650
P GS + P S T+P+A +P + T P D+ +SP+ + P
Sbjct: 2097 PSEGSPLLTSIPLS-----TTPVA---SPEASTLSTTPVDS-----NSPVITSTEVSSSP 2143
Query: 651 QPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPEL 710
P + S+R R S+P T + A +T P+ T V+ + E
Sbjct: 2144 IPTEGTSMQTSTYSDR---RTPLTSMPVSTTVVASSAISTLSTTPVDT--STPVTNSTEA 2198
Query: 711 LSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPP----PVAPKPAVK 766
S SEG M +S+ + + P PV+ P V
Sbjct: 2199 RSSPTTSEGTS------------------------MPTSTPSEGSTPFTSMPVSTMPVVT 2234
Query: 767 SSSSQ----PVTPVSPVWSPGVAPTQPP-----AFPTSNPSKGTV-VSSIKIAQPSYPPA 816
S +S PV +PV + A + P + PTS S+GT ++SI ++ +
Sbjct: 2235 SEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANS 2294
Query: 817 RPASTLNVAGPFKGPQAAVASQNYTPKPTV---STPTVNAVQPGAVGPSNELPGMSGRGA 873
STL+ +++ +P PT S PT + + P +P + A
Sbjct: 2295 E-VSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNT--PLTRMPVSTTMVA 2351
Query: 874 QLFAKRQSRMEKYVVDSDT-VQAHAARAQSPTP----SLPAS-WKYSSNVRAPPPVAYNP 927
S + D+ T V ++ SPT S+P S + S PV+ P
Sbjct: 2352 SF---ETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMP 2408
Query: 928 IHS---------------PSYPLAALKSQPSAAQPSKMGKK---KGKKPLNALDVMKHQP 969
+ S P S P+ A+ + + +G PL ++ V
Sbjct: 2409 VVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPV 2468
Query: 970 YQLNASLFTFQPPDAKDGLPQKSS------------VKVNSALAMKQALPPRPVNAASPT 1017
A + P D + + V +++A L PV+
Sbjct: 2469 VSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVA 2528
Query: 1018 NVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAK 1077
+ +AS++ + P ++ P + S + S +PTS E ++ + K A
Sbjct: 2529 SPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLAS 2588
Query: 1078 KSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTD 1120
T+ + S+P + S+SP + T S P++
Sbjct: 2589 SEASTLSTTPVDTSIP-VTTSTETSSSPTTAKDTSMPISTPSE 2630
Score = 38.9 bits (89), Expect = 0.031
Identities = 138/658 (20%), Positives = 226/658 (34%), Gaps = 108/658 (16%)
Query: 505 ITAQKEEDKVGGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHG-- 560
++A + GT S E ++ T +G+ TS + + +++ VS + + S
Sbjct: 1416 LSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKS-IPVSNTPVANSEAST 1474
Query: 561 LGHVPQQNGFSGTSETANIQRMVPMNRTA----KPFPGSVNQPATPFSPTRNMTSPIADF 616
L P + + TA P T+ P GS + P S T +S I
Sbjct: 1475 LSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSL 1534
Query: 617 PAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISV 676
P + + P +S+ SSP + S P S+
Sbjct: 1535 STTP--AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPL--------------TSL 1578
Query: 677 PAKRTGILQ-EAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDY 735
P ++ EA STT P + ++E T A G S
Sbjct: 1579 PVSTMLVVSSEANTLSTT------------PIDSKTQVTASTEASSSTTAEGSSMT---- 1622
Query: 736 LSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVW-----SPGVAPTQPP 790
+S +E + S + PVA P + S+ PV SPV S P +
Sbjct: 1623 ISTPSEGSPLLTSIPV---STTPVA-SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGT 1678
Query: 791 AFPTSNPSKG-TVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVS-- 847
+ PTS ++G T ++SI + + P A A + P S PT S
Sbjct: 1679 SMPTSTYTEGRTPLTSITVR--TTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEG 1736
Query: 848 TPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDT-VQAHAARAQSPTPS 906
T N+ P +P + + + S + +D+ T V SPT +
Sbjct: 1737 TSMPNSTPSEGTTPLTSIPVST---TPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTA 1793
Query: 907 LPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMK 966
S S+ P+ P+ S+ L A S+ S +
Sbjct: 1794 EGTSIPTSTLSEGMTPLTSTPV---SHTLVA-NSEASTLSTT------------------ 1831
Query: 967 HQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYS 1026
P N+ + T + + +S+ ++ AL PV+ + + + +++ +
Sbjct: 1832 --PVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLST 1889
Query: 1027 VPAYTSPP--SFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQ 1084
PA TS P ++ +SSP +A +PTS +E P S S T+
Sbjct: 1890 TPAVTSTPVTTYAQVSSSPTTAD--GSSMPTSTPREGRP--------PLTSIPVSTTTVA 1939
Query: 1085 ESG-RSLSLPGRSVPPPISTSPWVYQPTYSY-SSKPTDGLEKANKRPTPWEAAAKSPL 1140
S +LS P++ TYS SS PT PTP + +PL
Sbjct: 1940 SSEINTLSTTLADTRTPVT--------TYSQASSSPTTA--DGTSMPTPAYSEGSTPL 1987
Score = 38.9 bits (89), Expect = 0.031
Identities = 110/607 (18%), Positives = 206/607 (33%), Gaps = 93/607 (15%)
Query: 540 EEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGT----SETANIQRMVPMNRTAKPFPGS 595
E ++ T SK+ + S G S T SE + + +P++ T P +
Sbjct: 1589 EANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEA 1648
Query: 596 VNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPW 655
TP + + +P P + P ++ G
Sbjct: 1649 STLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEG-------------------- 1688
Query: 656 SQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQ 715
R S+ + T + A +T P+ V+ + E S
Sbjct: 1689 --------------RTPLTSITVRTTPVASSAISTLSTTPV--DNSTPVTTSTEARSSPT 1732
Query: 716 NSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSS----SSQ 771
SE G N S T PV+ P + S S+
Sbjct: 1733 TSE--------------------GTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSAT 1772
Query: 772 PVTPVSPVWSPGVAPTQP-----PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAG 826
P+ +PV + A + P + PTS S+G + + ASTL+
Sbjct: 1773 PIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTT- 1831
Query: 827 PFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKY 886
P V S + PT + T A + G S L + + + + +
Sbjct: 1832 PVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEG-STALTSIPVSTTTVASSETNTLSTT 1890
Query: 887 -VVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAA 945
V S V +A + SPT + +S S+ PP+ P+ + + + + + +
Sbjct: 1891 PAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTL 1950
Query: 946 QPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMK-- 1003
+ + P+ P + + + P +G +S+ +++ L +
Sbjct: 1951 ADT-------RTPVTTYSQASSSPTTADGT--SMPTPAYSEGSTPLTSMPLSTTLVVSSE 2001
Query: 1004 -QALPPRPVNAASP--TNVQASSVYSVPAYTS-PPSFFAEASSPVSASPVPVGIPTSPKQ 1059
L PV+ ++P T+ + SS + TS S +E ++P++ PV + S +
Sbjct: 2002 ASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEG 2061
Query: 1060 ESASSSYFVAPRPKFSAKK--SGVTIQESGRSLSLPGRSVP----PPISTSPWVYQPTYS 1113
+ S++ + ++ + S T + S ++S P P P+ST+P +
Sbjct: 2062 NTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEAST 2121
Query: 1114 YSSKPTD 1120
S+ P D
Sbjct: 2122 LSTTPVD 2128
Score = 36.6 bits (83), Expect = 0.16
Identities = 131/695 (18%), Positives = 230/695 (33%), Gaps = 113/695 (16%)
Query: 571 SGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPD 630
S SE + + +P++ T P + TP + + + + P
Sbjct: 2508 STASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTS 2567
Query: 631 AFSRGVSSPIAGPAQPPPWPQP-APWSQPAFYDSSERIASRDERISVPAKRTGILQEAKR 689
+S G + + P P A D+S + + E S P
Sbjct: 2568 TYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTA--------- 2618
Query: 690 RSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGT--------------GAGGDSGPEEDY 735
+ T+ P+ T E S L+S + + + T G S P
Sbjct: 2619 KDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTT-- 2676
Query: 736 LSLGAEACNFMQSSSAKQKTP-------PPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQ 788
AE + S+ ++ TP + + S+ PV +PV + A +
Sbjct: 2677 ----AEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSS 2732
Query: 789 PP-----AFPTSNPSKGT------VVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVAS 837
P + S PS G+ +VS++ +A A ST V + AS
Sbjct: 2733 PTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSE---ASTVSTTAVDTSIPVTTSTEAS 2789
Query: 838 QNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHA 897
+ T S PT + S L M + + + VD+ T +
Sbjct: 2790 SSPTTAEVTSMPTSTPSET-----STPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTS 2844
Query: 898 ARAQS-PTPS----LPASW-KYSSNVRAPPPVAYNPIHSP------------SYPLAAL- 938
+A S PT + +P S S + PV+ P+ S S P+
Sbjct: 2845 TKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTST 2904
Query: 939 --KSQPSAAQPSKMG---KKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSS 993
S P+ A+ + M + PL ++ V AS + P D + + +
Sbjct: 2905 EGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964
Query: 994 VKVNSALAMKQALP-------PRPVNAASPTNV-----QASSVYSVPAYTSPPSFFAEAS 1041
+ A ++P P+ + S + + +AS++ PA TS P + +
Sbjct: 2965 ASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEA 3024
Query: 1042 SPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRSVPPPI 1101
S + GIP S E ++ P + V I E+ + P S P +
Sbjct: 3025 SSSPTTAEGTGIPISTPSEGST------PLTSIPVSTTPVAIPEASTLSTTPVDSNSPVV 3078
Query: 1102 STSPWVYQP-----------TYSYSSKPTDGLEKANKRPTPWEAAAKSPLGLVD-DAFQP 1149
+++ P TYS S P G+ + TP ++A S L D P
Sbjct: 3079 TSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVST---TPVTSSAISTLSTTPVDTSTP 3135
Query: 1150 RNIQESIVANVVSAARRKVLPGPPEDWNERLSYIP 1184
++ ++ + P + + L+Y+P
Sbjct: 3136 VTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP 3170
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 63.5 bits (153), Expect = 1e-09
Identities = 110/502 (21%), Positives = 175/502 (34%), Gaps = 74/502 (14%)
Query: 594 GSVNQPATPFSPTRNMTSPIADFPAPP-----PYSAVTPPPDAFSRGVSSPIA------- 641
G P P+ P R P A APP P ++ PP A + S +
Sbjct: 980 GDTGSPRKPW-PERRPPRPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTS 1038
Query: 642 -----GPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPM 696
P PP P PA + P + S D +S P + ++ + P+
Sbjct: 1039 EATSDAPDTSPPTPDPASRTNPDLI-----LTSPDFALSTPD--SSVVPALTPEPSPTPL 1091
Query: 697 FTF-KEPKVSPNP--ELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQ 753
T KE P+ E+ SL SE + D+ P+ D + + +S
Sbjct: 1092 PTLPKELTSDPSTPSEVTSLSPTSEQVPES----DTTPDLDTTPYSSTVSEYSRSPDPSP 1147
Query: 754 KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSY 813
P P P + + P+T ++P +P PT P PT+ P T+ S I P+
Sbjct: 1148 SPHPTTTPDPTM---APDPITTLNPTVTPHF-PTTP--HPTTTPHPTTITHSTMIPDPTT 1201
Query: 814 PPARPASTLN----VAGPFKGPQAAVASQ-NYTPKPTVSTPTVNAVQPGAVGPSNELPGM 868
P +P +T+ + P PQ Q TP T PT P + S +P
Sbjct: 1202 TP-QPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTP-HPTTITHSTMIPDP 1259
Query: 869 SGRGAQLFAKRQSRM-EKYVVDSDTVQAHAARAQSPT----PSL---PASWKYSSNV--- 917
+ + + M T H PT P++ P + Y +
Sbjct: 1260 TTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDP 1319
Query: 918 -RAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNA-LDVMKHQPYQLNAS 975
P P +P +P +L + S K L+ L P+ +
Sbjct: 1320 TTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQ 1379
Query: 976 LFTFQPPDAKDGLPQKSSVKVN-SALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPP 1034
+ T +P A + P +SS + L+ + PPR + P T PP
Sbjct: 1380 IPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQS---------------PNLTPPP 1424
Query: 1035 SFFAEASSPVSASPVPVGIPTS 1056
+ ++S ++ SP P+ PT+
Sbjct: 1425 THTPHSASDLTVSPDPLLSPTA 1446
Score = 40.8 bits (94), Expect = 0.008
Identities = 61/237 (25%), Positives = 80/237 (33%), Gaps = 44/237 (18%)
Query: 576 TANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRG 635
T Q M T P P + P T PT T+P P P+ +TP P
Sbjct: 1260 TTTPQPFTTMQPTTMPHPTTTPHPTTTPHPT---TTP---HPTTTPHPTMTPDPTTTPYP 1313
Query: 636 VSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKP 695
++P P P P P S P +S+P L T KP
Sbjct: 1314 TTTP--DPTTTPHPTTPDPSSTPVI-----------TTVSLPTSLGTELSSPTLAPTVKP 1360
Query: 696 ------MFTFKEPKVS----PNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNF 745
FT P S P E L++S + T D ED+ +++ N
Sbjct: 1361 SLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNL 1420
Query: 746 MQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAP-TQPPAFP-TSNPSKG 800
TPPP S+S V+P P+ SP P PP P T P+ G
Sbjct: 1421 ---------TPPPT---HTPHSASDLTVSP-DPLLSPTAHPLDHPPLDPLTLGPTPG 1464
Score = 38.5 bits (88), Expect = 0.041
Identities = 65/319 (20%), Positives = 103/319 (32%), Gaps = 36/319 (11%)
Query: 758 PVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPAR 817
P P PA+ S SS+ +TP S + S + + PT +P+ T I + P + +
Sbjct: 1015 PGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLI-LTSPDFALST 1073
Query: 818 PASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFA 877
P S++ P P+ + PK S P+ + S ++P
Sbjct: 1074 PDSSV---VPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTT 1130
Query: 878 KRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPV-AYNPI---HSPSY 933
S + +Y +R+ P+PS P AP P+ NP H P+
Sbjct: 1131 PYSSTVSEY-----------SRSPDPSPS-PHPTTTPDPTMAPDPITTLNPTVTPHFPTT 1178
Query: 934 PLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSS 993
P P+ S M P QP+ P PQ +
Sbjct: 1179 PHPTTTPHPTTITHSTMIPDPTTTP---------QPFTTITHSTMIPDPTT---TPQPFT 1226
Query: 994 VKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGI 1053
+ P P PT + S++ +P T+ P F P
Sbjct: 1227 TM--QPTTTPHSTTPHPTTTPHPTTITHSTM--IPDPTTTPQPFTTMQPTTMPHPTTTPH 1282
Query: 1054 PTSPKQESASSSYFVAPRP 1072
PT+ + + P P
Sbjct: 1283 PTTTPHPTTTPHPTTTPHP 1301
Score = 35.0 bits (79), Expect = 0.45
Identities = 56/302 (18%), Positives = 99/302 (32%), Gaps = 33/302 (10%)
Query: 573 TSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADF--PAPPPYSAVTPPPD 630
TS+ + + ++ T++ P S P +P + S + P+P P+ TP P
Sbjct: 1099 TSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPT 1158
Query: 631 AFSRGVS--SPIAGPAQPPPWPQPAPWSQPAFYDSSERI----------ASRDERISVPA 678
++ +P P P P P P S I + +P
Sbjct: 1159 MAPDPITTLNPTVTP-HFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPD 1217
Query: 679 KRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSL 738
T + TT P T P +P+P ++ T + + + ++
Sbjct: 1218 PTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTIT--------HSTMIPDPTTTPQPFTTM 1269
Query: 739 GAEACNFMQSSSAKQKTP-PPVAPKPAV---KSSSSQPVTPVSPVWSPGVAPTQPPAFPT 794
++ TP P P P + + P T P +P PT P T
Sbjct: 1270 QPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPD--PTTTPHPTT 1327
Query: 795 SNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAV 854
+PS V++++ + + P PQ + P P ST + +
Sbjct: 1328 PDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTA----PAPHTSTSQIPTL 1383
Query: 855 QP 856
+P
Sbjct: 1384 EP 1385
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 62.0 bits (149), Expect = 3e-09
Identities = 30/78 (38%), Positives = 51/78 (65%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
Query: 69 VIKLMESITDSLQMLIKR 86
++S + +L + +++
Sbjct: 65 AQNKIKSASYNLSLTLQK 82
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 62.0 bits (149), Expect = 3e-09
Identities = 30/78 (38%), Positives = 51/78 (65%)
Query: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
+++TG PWGFRLQGGK+ PL +++I SKA+ S L +GD VV+I+G +T+ E
Sbjct: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
Query: 69 VIKLMESITDSLQMLIKR 86
++S + +L + +++
Sbjct: 65 AQNKIKSASYNLSLTLQK 82
Score = 38.5 bits (88), Expect = 0.041
Identities = 78/345 (22%), Positives = 119/345 (34%), Gaps = 34/345 (9%)
Query: 817 RPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSN-------ELPGMS 869
RP A P + P + Q + P A+ S E+ G+
Sbjct: 85 RPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQERFNPSALKDSALSTHKPIEVKGLG 144
Query: 870 GRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIH 929
G+ + A+ + + Y D+ + A A +AQ+ S +A +
Sbjct: 145 GKATIIHAQYNTPISMYSQDA-IMDAIAGQAQAQGSDFSGSLPIKD-------LAVDSA- 195
Query: 930 SPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDA--KDG 987
SP Y A +KSQ +P + ++ N Q+ + F P + +
Sbjct: 196 SPVYQ-AVIKSQN---KPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS 251
Query: 988 LPQKSS----VKVNSALAMKQALPPRPVNAASPTNVQAS-----SVYS-VPAYTSPPSFF 1037
PQ SS V +SA A + P A V + SVY VPA T PS
Sbjct: 252 RPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPG 311
Query: 1038 AEAS-SPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPGRS 1096
A S +P + SP P P+ + S P P + S S++ G
Sbjct: 312 ANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGP 371
Query: 1097 VPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPLG 1141
P S PWV ++S P +K+ P A +P G
Sbjct: 372 AEPA-SRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAG 415
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 9/78 (11%)
Query: 584 PMNRTAKPFPGSVNQPATPFSPTRNMTSPIADF-PAPPPYSAVTPPPD---AFSRGVSSP 639
P T P P PA ++P SP+ + P+P P +P P+ A S S
Sbjct: 316 PTPYTPSPAPAYTPSPAPAYTP-----SPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG 370
Query: 640 IAGPAQPPPWPQPAPWSQ 657
A PA PPW +SQ
Sbjct: 371 PAEPASRPPWVTDDSFSQ 388
Score = 31.2 bits (69), Expect = 6.5
Identities = 30/123 (24%), Positives = 45/123 (36%), Gaps = 11/123 (8%)
Query: 729 SGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPV----WSPGV 784
S P+ S A + + ++ + P APKP V +++S + PV +SP
Sbjct: 251 SRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP 310
Query: 785 APTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKP 844
P T +P+ S PS P S P P NY P P
Sbjct: 311 GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAP-------NYNPAP 363
Query: 845 TVS 847
+V+
Sbjct: 364 SVA 366
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 61.2 bits (147), Expect = 6e-09
Identities = 140/600 (23%), Positives = 204/600 (34%), Gaps = 82/600 (13%)
Query: 571 SGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPD 630
SG N + + R P G+ P PT + P+ P P
Sbjct: 1336 SGLPAVLNPRPTLTPGRLPTPTLGTARAPM----PTPTLVRPLLKLVHSPSPEVSASAPG 1391
Query: 631 AFSRGVSSPIAGPAQ---PPPWPQPAPWSQPAFYDSSERIA---SRDERISVPAKRTGIL 684
A +SSP+ P+ P P P P S P S ++ S ISVP
Sbjct: 1392 AAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPA 1451
Query: 685 QEAKRRSTTKPMFTFKEPKV---SPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAE 741
+ P+ S P L ++ + G G S P L+LG
Sbjct: 1452 SAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGAS-PSASALTLGLA 1510
Query: 742 ACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPV-SPVWSPGVAPTQP-PAFPTSNPSK 799
+ SSS P +AP + + V P SPV P A P P+ P P++
Sbjct: 1511 TAPSL-SSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQ 1569
Query: 800 GTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAV 859
++++ A + A P + P PQ A+ + + P P ++ V A PGA
Sbjct: 1570 ASLLAPASSASQAL--ATPLA------PMAAPQTAILAPS--PAPPLAPLPVLAPSPGA- 1618
Query: 860 GPSNELPGMSGRGAQLFAKRQSRMEKYVVDSD--TVQAHAARAQSPTPSLPASWKYSSNV 917
A + A Q+ + S T A A+ +PTP L S S+
Sbjct: 1619 -------------APVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPS---STQT 1662
Query: 918 RAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPY-QLNASL 976
P PV +P+ SP+ +Q A P+ G P L + P
Sbjct: 1663 MLPAPVP-SPLPSPA------STQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQT 1715
Query: 977 FTFQPPDAKDGLP-QKSSVKVNSALAMKQAL---PPRPVNAASPTNVQASSVYSVPAYTS 1032
+ P + P Q S+ L Q L P P+ ASP + ++ +S
Sbjct: 1716 LSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASS 1775
Query: 1033 PPSFFAEAS-SPVSASPVPVGI------------PTSPKQESASSSYFV------APRPK 1073
S A AS ++ SP PV P S + ++ +S V AP P
Sbjct: 1776 SASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPV 1835
Query: 1074 FSAKKSGVTIQESGRSLSLPGRSVPPPISTS-----PWVYQPTYSYSSKPTDGLEKANKR 1128
+ V+ E G PP +TS P P S D LE+ KR
Sbjct: 1836 TMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKR 1895
Score = 55.1 bits (131), Expect = 4e-07
Identities = 129/569 (22%), Positives = 194/569 (34%), Gaps = 73/569 (12%)
Query: 613 IADFPAPPPYSAV---TPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIAS 669
+A P P P S + TP G+S P+A PP + R A
Sbjct: 1263 VAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMV-----NNTGVVKIVVRQAP 1317
Query: 670 RDERISVPA-------KRTGILQEAKRRSTTKP-------MFTFKEPKVSPN--PELLSL 713
RD VP +G+ R T P + T + P +P LL L
Sbjct: 1318 RDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKL 1377
Query: 714 LQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPV 773
+ + PE + GA P P A P +SS
Sbjct: 1378 VHSPS------------PEVSASAPGAAPLTISSPLHVPSSLPGP-ASSPMPIPNSSPLA 1424
Query: 774 TPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQA 833
+PVS S ++ + P + PT+ P+ + +I I+ P A + L P P
Sbjct: 1425 SPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVV 1484
Query: 834 AVASQNYTPKPTVSTPTVNAVQPG-AVGP---SNELPGMSGRGAQLFAKRQSRMEKYVVD 889
A + P+ ++P+ +A+ G A P S++ PG A +
Sbjct: 1485 PAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPA 1544
Query: 890 SDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSK 949
V A+ SP PS P +++ AP A + +P P+AA ++ A P+
Sbjct: 1545 CSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPA- 1603
Query: 950 MGKKKGKKPLNALDVMKHQP--YQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALP 1007
PL L V+ P + AS T P A P ++LA +P
Sbjct: 1604 -------PPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTP-------GTSLASASPVP 1649
Query: 1008 -PRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSY 1066
P PV A S T + P SP S A +P A + P+ +
Sbjct: 1650 APTPVLAPSSTQTMLPAPVPSP-LPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQ 1708
Query: 1067 FVAPRPKFSAKKSGVTIQESGRSLSL-PGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKA 1125
P S + + ++LSL PG PP+ PT + S P L A
Sbjct: 1709 GPFPTQTLSLTPASSLVPTPAQTLSLAPG----PPLG-------PTQTLSLAPAPPLAPA 1757
Query: 1126 NK-RPTPWEAAAKSPLGLVDDAFQPRNIQ 1153
+ P P +P P ++Q
Sbjct: 1758 SPVGPAPAHTLTLAPASSSASLLAPASVQ 1786
Score = 48.5 bits (114), Expect = 4e-05
Identities = 69/288 (23%), Positives = 104/288 (36%), Gaps = 38/288 (13%)
Query: 563 HVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQP-----------------ATPFSP 605
HVP G + T A +VP + A PFP + N ATP +P
Sbjct: 1533 HVP---GLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589
Query: 606 -TRNMTSPIADFPAPP--PYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYD 662
T+ +A PAPP P + P P A +P+ +Q P P AP S P
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGA------APVLASSQTPV-PVMAPSSTPGTSL 1642
Query: 663 SSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKR- 721
+S + P+ +L P T ++ P L L S +
Sbjct: 1643 ASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPAST---QTLALAPALAPTLGGSSPSQT 1699
Query: 722 -GTGAGGDSGP-EEDYLSLGAEACNFMQSSSAKQKTP-PPVAPKPAVKSSSSQPVTPVSP 778
G G GP LSL + + P PP+ P + + + P+ P SP
Sbjct: 1700 LSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASP 1759
Query: 779 VW-SPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVA 825
V +P T PA +++ V ++ ++ P PA+ +A
Sbjct: 1760 VGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLA 1807
Score = 46.6 bits (109), Expect = 2e-04
Identities = 154/676 (22%), Positives = 223/676 (32%), Gaps = 167/676 (24%)
Query: 585 MNRTAKPFPGS-------VNQPATPFSPTRNMTSP---IADFPAPPPYSAVTPPPDAFSR 634
+NR +P P VN P P P P ++ P P P V P S
Sbjct: 994 VNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSA 1053
Query: 635 GVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTK 694
+ P PA PP P P QP +G L
Sbjct: 1054 SPAGPPLIPASRPPGPVLLPPLQP---------------------NSGSL---------- 1082
Query: 695 PMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQK 754
P+V P+P L +L G S P LSL K
Sbjct: 1083 -------PQVLPSP--LGVL-----------SGTSRPPTPTLSL-------------KPT 1109
Query: 755 TPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYP 814
P PV PA SS + P++ PG T PPA T+ + T ++ A P+
Sbjct: 1110 PPAPVRLSPAPPPGSSSLLKPLTV--PPGY--TFPPAAATTTST--TTATATTTAVPAPT 1163
Query: 815 PARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGP------SNELPGM 868
PA L+ + P V S P NA G P N+L
Sbjct: 1164 PAPQRLILSPDMQARLPSGEVVSIGQLAS-LAQRPVANA---GGSKPLTFQIQGNKLTLT 1219
Query: 869 SGRGAQLFAKRQSRMEKYVVDSDTV---------QAHAA--RAQSPTPS-LPASWKYSSN 916
+ QL + +++ VV + AH A +A +PTP P S SS
Sbjct: 1220 GAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSST 1279
Query: 917 VRAPP-------PVAYNPIH----------------------SPSYPLAALKSQPSAAQP 947
P P+A N + +P PLA PS+ P
Sbjct: 1280 PSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLP 1339
Query: 948 SKMGKK----KGKKPLNALDVMK---HQPYQLN--ASLFTFQPPDAKDGLPQKSSVKVNS 998
+ + + G+ P L + P + L P+ P + + ++S
Sbjct: 1340 AVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISS 1399
Query: 999 ALAMKQALP-----PRPVNAASPTNVQASSVYSVPAYTS-----PPSFFAEASSPVSASP 1048
L + +LP P P+ +SP SS SVP +S P + A AS+P++
Sbjct: 1400 PLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLT--- 1456
Query: 1049 VPVGIPTSPKQESASSSYFVAP--RPKFSAKKSGVTIQESGRSLSLP----GRSVPPPIS 1102
+P+ P + + V P P A ++ SG S S G + P +S
Sbjct: 1457 IPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLS 1516
Query: 1103 TS-----PWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSPLGLVDDAFQPRNIQESIV 1157
+S P + PT S+ + A +A SP A P Q S++
Sbjct: 1517 SSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPF---PSAPNPAPAQASLL 1573
Query: 1158 ANVVSAARRKVLPGPP 1173
A SA++ P P
Sbjct: 1574 APASSASQALATPLAP 1589
Score = 32.7 bits (73), Expect = 2.2
Identities = 55/228 (24%), Positives = 79/228 (34%), Gaps = 41/228 (17%)
Query: 437 FLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDI-------EKKLNRGDKMEMLPDTTG 489
FL AS EV E L ++ + D D ++ E+ GD+ TG
Sbjct: 2319 FLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSC---GTG 2375
Query: 490 KGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESVRTQSS 549
G +K+ + ++ + E G A+T G T + S T
Sbjct: 2376 GGTHRRSKKAKAPERPGTRVSERLRGAR-------AETQGANHTPVISAHQTRSTTTPPR 2428
Query: 550 VSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNM 609
S + V P+ + S A I +VP+ +A P P S P T
Sbjct: 2429 CSPARERVPRP---APRPRP-TPASAPAAIPALVPVPVSA-PVPISAPNPITIL------ 2477
Query: 610 TSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGP---AQPPPWPQPAP 654
P+ P+PPP S + P SSP P PPP P P
Sbjct: 2478 --PVHILPSPPPPSQIPP--------CSSPACTPPPACTPPPAHTPPP 2515
Score = 32.3 bits (72), Expect = 2.9
Identities = 93/493 (18%), Positives = 174/493 (35%), Gaps = 82/493 (16%)
Query: 308 VDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSR---PHKHRA----RHARLRR 360
+D P G A L F++S + P+ EK H+ KH A R A LR+
Sbjct: 57 LDGP-PGPPDGATVPLEGFSLSQAADLANKGPKWEKSHAEIAEQAKHEAEIETRIAELRK 115
Query: 361 SESLSEKQVKEAKSK----------CKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLV 410
S K++ + C+ + L D ++R +R +V
Sbjct: 116 EGFWSLKRLPKVPEPPRPKGHWDYLCEEMQWLSADFAQ---------ERRWKRGVARKVV 166
Query: 411 SYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVD 470
E + +EE +E+ ++ + ++ ++ + S+V+ +VV F S L +
Sbjct: 167 RMVIRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVE---KVVQFKQQSRLEE 223
Query: 471 IEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGL 530
KK ++ + T K + + ++ + K G +P +A +
Sbjct: 224 KRKKA-LDLHLDFIVGQTEKYSDLLSQ------SLNQPLTSSKAGSSPCLGSSSAASSPP 276
Query: 531 RTTT-------SYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRM- 582
+ +Q +E+E + + IEV QQ G ++ I+ +
Sbjct: 277 PPASRLDDEDGDFQPQEDEEEDDEET-----IEVEE------QQEGNDAEAQRREIELLR 325
Query: 583 ----VPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSS 638
+P+ + P + + P SP++ +S +D P A PP +
Sbjct: 326 REGELPLEELLRSLPPQLLEG--PSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLE--IKP 381
Query: 639 PIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFT 698
P + Q P F + E ++ I+ + G + A S
Sbjct: 382 PPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELA---- 437
Query: 699 FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPP 758
+E ++S + LLQ G G+G +ED + + C + P
Sbjct: 438 -REGELS----MEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDC---------EPEGPV 483
Query: 759 VAPKPAVKSSSSQ 771
A +P + SSSQ
Sbjct: 484 EAEEPPQEDSSSQ 496
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 61.2 bits (147), Expect = 6e-09
Identities = 141/632 (22%), Positives = 217/632 (34%), Gaps = 129/632 (20%)
Query: 609 MTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIA 668
M S A + P P + P + G +A +PP P A SQ A +SE +
Sbjct: 379 MVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRA---ASEDMT 435
Query: 669 SRDERISVPAKR-------------TGILQEAKRRSTT---------------------- 693
S +ER+ + + T I + K R T
Sbjct: 436 SDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVF 495
Query: 694 ----KPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNF---- 745
+ FT P + P P + GK G G+ S S + A +F
Sbjct: 496 SPVIRSSFTHCRPPLDPEPPGPPDPPVAFGK-GYGSAPSSSASSPASSSASAATSFSLGS 554
Query: 746 ---------MQSSSAKQKTPPPVAPKPAVKSSSSQ--PVTPVS-----PVWSPGVAPTQP 789
S++ + PPP A PA S +++ P+ P + P G+ P P
Sbjct: 555 GTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP 614
Query: 790 PAFPTSNPSKGTVVS------------------------SIKIAQPSYPPARPASTL--N 823
G ++ S+ P+ P +RPA+T+ N
Sbjct: 615 SVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTN 674
Query: 824 VAGPFKGPQAAVASQNY-TPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSR 882
V P +AS+ + T ++P A +G + +PG S G L
Sbjct: 675 VVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSL------- 727
Query: 883 MEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAA----- 937
V SD +A A SP P L A + +AP V + +P Y A
Sbjct: 728 -----VYSDK---KSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
Query: 938 --LKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVK 995
+ P + G G P + + QP L + Q LPQ+ V
Sbjct: 780 FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
Query: 996 VNSALA--MKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGI 1053
A A K A P P +PT S +++P TS A++P P+ +
Sbjct: 840 PAPAPAPGTKAAAPSGP----APTT---SIRFTLPPGTSTNGKVLAATAPTPGIPILQSV 892
Query: 1054 PTSPKQESASSSYFVAPRPKFSAK--KSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPT 1111
P++P ++ S S AP P SA+ V + + S+S+ G P+ P V P
Sbjct: 893 PSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPL---PLVSPP- 948
Query: 1112 YSYSSKPTDGLEKANKRPTPWEAAAKSPLGLV 1143
+S +G + +K +P GLV
Sbjct: 949 --FSVPVQNGAQPPSKIIQLTPVPVSTPSGLV 978
Score = 47.0 bits (110), Expect = 1e-04
Identities = 112/489 (22%), Positives = 173/489 (35%), Gaps = 108/489 (22%)
Query: 722 GTGAGGDSGPEEDY----LSLGA--------EACNFMQSSSAKQKTPPPVAPKPAVKS-- 767
G+GAG SGP L GA + + + + + P AP P K+
Sbjct: 793 GSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAA 852
Query: 768 -SSSQPVTPVSPVWSPG-------VAPTQPP-------AFPTSNPSKGTVVSSIKIAQPS 812
S P T + PG +A T P + P++ P K VS ++ P
Sbjct: 853 PSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPG 912
Query: 813 -----------YPPARPASTLNVAG-----PFKGPQAAVASQNYTPKPTVS---TPTVNA 853
P A P+ ++ G P P +V QN P+ TP +
Sbjct: 913 GSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVS 972
Query: 854 VQPGAVGPSNE--LPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASW 911
G V P + LPG + + ++ +R+ YV + HA P + PAS
Sbjct: 973 TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRIT-YV---QSAGGHAL----PLGTSPAS- 1023
Query: 912 KYSSNVRAPPPVAYNPIHSPSYPLAAL-KSQPSAAQPSKMGKKKGKKPLNALDVMKHQPY 970
+A +Y P S + +L S P+ QP G+ PL A P
Sbjct: 1024 -----SQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSA---GQAPLLA-------PG 1068
Query: 971 QLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAA---SPTNVQASSVYSV 1027
Q+ S P LP + + + P P ++A P+ S VY+V
Sbjct: 1069 QVGVS------PVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTV 1122
Query: 1028 PAYTSPP-SFFAEASSPVSASPVPVGIPTSPKQESASSSY-FVAPRPKFSAKKSGVTIQE 1085
T+PP + P A+ P P + S +Y VAP+ + + K+ ++
Sbjct: 1123 ATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKA 1182
Query: 1086 SGRSLSL----------PGRSVPPPISTSPWVYQPTYSYSSKPTDGLEKANKRPTP---- 1131
+ S+ + PG + P+ P V +PT P LE P P
Sbjct: 1183 AIASIPVGSFEAGASGRPGPAPRQPLEPGP-VREPT-----APESELEGQPTPPAPPPLP 1236
Query: 1132 --WEAAAKS 1138
W A+S
Sbjct: 1237 ETWTPTARS 1245
Score = 45.4 bits (106), Expect = 3e-04
Identities = 98/420 (23%), Positives = 149/420 (35%), Gaps = 84/420 (20%)
Query: 571 SGTSETANIQRMVPMNRTAK--------PFPGSVNQPATPFSPTRNMTSPIADFPAPPPY 622
SG + T +I+ +P + P PG + P +P S ++ APPP
Sbjct: 854 SGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQS-VSPVQAPPPG 912
Query: 623 SAVTPPPDAFSRGVSSPI-----AGPAQPPPWPQPAPWSQPAFYDS---SERIASRDERI 674
+ P +++P G QP P P P+S P + S+ I +
Sbjct: 913 GSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSP-PFSVPVQNGAQPPSKIIQLTPVPV 971
Query: 675 SVPAKRTGILQEAKRRSTTKPMFTFKEPKVS-PNPELLSLLQNSEGKR---GTG-AGGDS 729
S P+ L A T P T + KV P+ ++ +Q++ G GT A +
Sbjct: 972 STPSGLVPPLSPA-----TLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQA 1026
Query: 730 GPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTP----VSPVWSPGV- 784
G Y + A F + P +P + + + + P VSPV SP +
Sbjct: 1027 GTVTSYGPTSSVALGFTSLGPSG-----PAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLP 1081
Query: 785 ----APTQP--PAFPTSNPSKGTVVSSIKIAQPSYPPAR-----------PASTLNVAGP 827
AP P AF + +P+ SS +AQPS P PA+T+ GP
Sbjct: 1082 PACAAPGGPVITAFYSGSPAP---TSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGP 1138
Query: 828 FKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYV 887
A A + P T + T + V P A PS + P
Sbjct: 1139 PAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAP--------------------- 1177
Query: 888 VDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQP 947
+ AA A P S A P+ P+ P+ P + L+ QP+ P
Sbjct: 1178 -----QKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAP 1232
Score = 33.5 bits (75), Expect = 1.3
Identities = 60/248 (24%), Positives = 78/248 (31%), Gaps = 91/248 (36%)
Query: 593 PGSVNQPATPFSPTRNMTSPIADFPAPPPY----------SAVTPPPDAFSRGVSSPIA- 641
PG V +P P S +P PAPPP S PPP P
Sbjct: 1210 PGPVREPTAPESELEGQPTP----PAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETM 1265
Query: 642 ---------------------GPAQPPPWPQPAPWSQP----------AFYDSSER--IA 668
G PP P PAP P A D+ ER A
Sbjct: 1266 ASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAA 1325
Query: 669 SRDERISV---PAKRT------GILQEAKRRSTTKPMFTFKEPKVSPNPELLSL------ 713
+++ V P K+T +L E + F+ +V P+P L SL
Sbjct: 1326 GTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRA 1385
Query: 714 -LQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVK---SSS 769
L + KR DS PE+ P +PK ++ S S
Sbjct: 1386 ILGSYRKKRKNSTDLDSAPED------------------------PTSPKRKMRRRSSCS 1421
Query: 770 SQPVTPVS 777
S+P TP S
Sbjct: 1422 SEPNTPKS 1429
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 60.8 bits (146), Expect = 8e-09
Identities = 32/92 (34%), Positives = 57/92 (61%), Gaps = 2/92 (2%)
Query: 2 GTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKAS-GSGLCEGDEVVSINGNP 60
G+ ++ + + GGAPWGF L+GG E +PL V+KI + KA+ + GDE+V+ING P
Sbjct: 6 GSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTP 65
Query: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGIS 92
+ E + L++ L+++++R ++ +S
Sbjct: 66 LYG-SRQEALILIKGSFRILKLIVRRRNAPVS 96
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 60.8 bits (146), Expect = 8e-09
Identities = 127/587 (21%), Positives = 193/587 (32%), Gaps = 60/587 (10%)
Query: 565 PQQNGFSGTSETANIQRMVPMNRTAK-PFPGSVNQ-PATPFSPTRNMTSPIADFPAPPPY 622
P++ + T E A P T K P P + P TP P T+P P P
Sbjct: 259 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP--TTPKKPAPTTPKE 316
Query: 623 SAVTPPPDAFSRGVSSPIAGPAQPPPW----PQPAPWSQPAFYDSSERIASRDERISVPA 678
A T P + P +P P P P +PA E + + PA
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE---PA 373
Query: 679 KRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSL 738
T K S T P KEP +P + E T + P+E +
Sbjct: 374 PTT-----TKEPSPTTP----KEP--APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422
Query: 739 GAEACNFMQSSSAKQ--KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGV----APTQPPAF 792
E A K P P PK ++ +P + +P APT P
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482
Query: 793 PTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVN 852
+ P K T + K+A + P +PA T P+ + P PT TP
Sbjct: 483 APTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPAPT--TPKAA 538
Query: 853 AV----QPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAA---RAQSPTP 905
A +P P P A K + T++ A + +P
Sbjct: 539 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 598
Query: 906 SLPASWKYSSNVRAPPPVAYNPIHS----PSYPLAALKSQPSAAQPSKMGKKKGKKPLNA 961
P + K ++ P P + P P +P+ P K+P
Sbjct: 599 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 658
Query: 962 LDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQA 1021
K P +L A T P P ++ K + K+ P P A PT +
Sbjct: 659 TP-KKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA-PTTPET 715
Query: 1022 ----SSVYSVPAYTSPPSFFA----EASSPVSASPVPVGIPTSPKQESASSSYFVAPRPK 1073
+S S P T P+ E++ +SA P P + SPK+ ++ A
Sbjct: 716 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA---- 771
Query: 1074 FSAKKSGVTIQESGRSLSLPGRSVPPPISTSPWVYQPTYSYSSKPTD 1120
A K +T ++ R+ P + +P + + T + + K T+
Sbjct: 772 --ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTE 816
Score = 55.8 bits (133), Expect = 2e-07
Identities = 137/649 (21%), Positives = 207/649 (31%), Gaps = 86/649 (13%)
Query: 532 TTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAK- 590
TTT+ Q + +T S+ IE + P + + A P T K
Sbjct: 156 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 215
Query: 591 PFPGSVNQPA--TPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPP 648
P P + +PA TP PT P P + P + PA P
Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 275
Query: 649 W-PQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTT----------KPMF 697
P P +PA + + E K+ + TT +P
Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 335
Query: 698 TFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQ--KT 755
T KEP + E + P+E + E A K+
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395
Query: 756 PPPVAPKPAVKSSSSQPVTP--VSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSY 813
P +PA ++ S P TP SP + APT P + P K + + A +
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT- 454
Query: 814 PPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGA 873
P PA T T KP +TP +P P P +
Sbjct: 455 -PKEPAPTT------------------TKKPAPTTPK----EPAPTTPKETAPTTPKKLT 491
Query: 874 QLFAKRQSRMEKYVVDSDTVQAHA-ARAQSPTPSLPASWKYSSNVRAPPPVAYNPI-HSP 931
++ + T + A + PTP+ P ++ A P P +P
Sbjct: 492 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 932 SYPLAALKSQPSAAQPSKMG--KKKGKKPLNALD-----VMKHQPYQLNASLFTFQPPDA 984
P +P+ P + KG P + K P +L A T +P
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKEPTST 610
Query: 985 KDGLPQKSSVKVNSALAMKQALPPRPVNAASPT-NVQASSVYSVPAYTSP---------P 1034
P ++ K + K+ P P A T A + PA T+P P
Sbjct: 611 TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 670
Query: 1035 SFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQESGRSLSLPG 1094
+ +S S P PT+PK+ + ++ AP + KK T E+
Sbjct: 671 TTTKGPTSTTSDKPA----PTTPKETAPTTPKEPAPT---TPKKPAPTTPET-------- 715
Query: 1095 RSVPPP----ISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSP 1139
PPP +ST +PT + S P + + + PTP +A SP
Sbjct: 716 ---PPPTTSEVSTPTTTKEPTTIHKS-PDESTPELSAEPTP-KALENSP 759
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,053,182
Number of Sequences: 37866
Number of extensions: 3332115
Number of successful extensions: 24432
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 1121
Number of HSP's that attempted gapping in prelim test: 15536
Number of HSP's gapped (non-prelim): 6908
length of query: 1261
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1147
effective length of database: 13,930,794
effective search space: 15978620718
effective search space used: 15978620718
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.