BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|188536004 zinc finger protein 469 [Homo sapiens] (3925 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|188536004 zinc finger protein 469 [Homo sapiens] 8143 0.0 gi|163965366 nascent polypeptide-associated complex alpha subuni... 143 4e-33 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 115 9e-25 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 107 2e-22 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 107 3e-22 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 105 7e-22 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 103 4e-21 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 103 4e-21 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 102 6e-21 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 102 1e-20 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 101 1e-20 gi|91208420 bassoon protein [Homo sapiens] 99 6e-20 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 99 1e-19 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 95 2e-18 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 95 2e-18 gi|95147555 microtubule-associated protein 1A [Homo sapiens] 94 2e-18 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 94 3e-18 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 94 3e-18 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 94 3e-18 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 92 1e-17 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 91 2e-17 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 91 2e-17 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 91 2e-17 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 91 3e-17 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 89 7e-17 gi|160707881 formin 2 [Homo sapiens] 88 2e-16 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 88 2e-16 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 86 6e-16 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 86 6e-16 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 86 6e-16 >gi|188536004 zinc finger protein 469 [Homo sapiens] Length = 3925 Score = 8143 bits (21130), Expect = 0.0 Identities = 3925/3925 (100%), Positives = 3925/3925 (100%) Query: 1 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL Sbjct: 1 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60 Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY Sbjct: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120 Query: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF 180 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF Sbjct: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF 180 Query: 181 HRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAE 240 HRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAE Sbjct: 181 HRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAE 240 Query: 241 NSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNG 300 NSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNG Sbjct: 241 NSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNG 300 Query: 301 PLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGA 360 PLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGA Sbjct: 301 PLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGA 360 Query: 361 AHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP 420 AHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP Sbjct: 361 AHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP 420 Query: 421 GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSA 480 GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSA Sbjct: 421 GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSA 480 Query: 481 PLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSS 540 PLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSS Sbjct: 481 PLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSS 540 Query: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT 600 QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT Sbjct: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT 600 Query: 601 AGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTH 660 AGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTH Sbjct: 601 AGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTH 660 Query: 661 YQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLS 720 YQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLS Sbjct: 661 YQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLS 720 Query: 721 SASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP 780 SASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP Sbjct: 721 SASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP 780 Query: 781 RVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKL 840 RVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKL Sbjct: 781 RVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKL 840 Query: 841 DSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPP 900 DSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPP Sbjct: 841 DSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPP 900 Query: 901 LPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDS 960 LPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDS Sbjct: 901 LPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDS 960 Query: 961 GGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPE 1020 GGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPE Sbjct: 961 GGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPE 1020 Query: 1021 ETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG 1080 ETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG Sbjct: 1021 ETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG 1080 Query: 1081 PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRS 1140 PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRS Sbjct: 1081 PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRS 1140 Query: 1141 PQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP 1200 PQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP Sbjct: 1141 PQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP 1200 Query: 1201 ETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTA 1260 ETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTA Sbjct: 1201 ETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTA 1260 Query: 1261 PHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSK 1320 PHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSK Sbjct: 1261 PHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSK 1320 Query: 1321 ISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP 1380 ISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP Sbjct: 1321 ISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP 1380 Query: 1381 PASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPL 1440 PASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPL Sbjct: 1381 PASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPL 1440 Query: 1441 YGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTC 1500 YGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTC Sbjct: 1441 YGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTC 1500 Query: 1501 PPERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPREL 1560 PPERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPREL Sbjct: 1501 PPERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPREL 1560 Query: 1561 AEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVE 1620 AEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVE Sbjct: 1561 AEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVE 1620 Query: 1621 AVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLC 1680 AVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLC Sbjct: 1621 AVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLC 1680 Query: 1681 QAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL 1740 QAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL Sbjct: 1681 QAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL 1740 Query: 1741 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS 1800 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS Sbjct: 1741 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS 1800 Query: 1801 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH Sbjct: 1801 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860 Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG Sbjct: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920 Query: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS 1980 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS Sbjct: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS 1980 Query: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL 2040 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL Sbjct: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL 2040 Query: 2041 ALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLG 2100 ALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLG Sbjct: 2041 ALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLG 2100 Query: 2101 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG 2160 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG Sbjct: 2101 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG 2160 Query: 2161 AEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDS 2220 AEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDS Sbjct: 2161 AEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDS 2220 Query: 2221 TLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDP 2280 TLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDP Sbjct: 2221 TLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDP 2280 Query: 2281 QSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEG 2340 QSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEG Sbjct: 2281 QSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEG 2340 Query: 2341 EMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRN 2400 EMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRN Sbjct: 2341 EMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRN 2400 Query: 2401 ASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLS 2460 ASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLS Sbjct: 2401 ASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLS 2460 Query: 2461 RHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSH 2520 RHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSH Sbjct: 2461 RHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSH 2520 Query: 2521 VTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAE 2580 VTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAE Sbjct: 2521 VTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAE 2580 Query: 2581 KREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAM 2640 KREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAM Sbjct: 2581 KREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAM 2640 Query: 2641 ASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDR 2700 ASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDR Sbjct: 2641 ASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDR 2700 Query: 2701 MLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEG 2760 MLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEG Sbjct: 2701 MLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEG 2760 Query: 2761 VWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKD 2820 VWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKD Sbjct: 2761 VWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKD 2820 Query: 2821 PPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARL 2880 PPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARL Sbjct: 2821 PPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARL 2880 Query: 2881 PTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEPSRE 2940 PTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEPSRE Sbjct: 2881 PTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEPSRE 2940 Query: 2941 AGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPEPPSLERERC 3000 AGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPEPPSLERERC Sbjct: 2941 AGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPEPPSLERERC 3000 Query: 3001 DGGLPGNTHLLPLRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQ 3060 DGGLPGNTHLLPLRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQ Sbjct: 3001 DGGLPGNTHLLPLRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQ 3060 Query: 3061 SRRTEEAAGAGRAQGRGRPAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPTCYMC 3120 SRRTEEAAGAGRAQGRGRPAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPTCYMC Sbjct: 3061 SRRTEEAAGAGRAQGRGRPAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPTCYMC 3120 Query: 3121 VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNEHLREHAVRFARRGQAR 3180 VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNEHLREHAVRFARRGQAR Sbjct: 3121 VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNEHLREHAVRFARRGQAR 3180 Query: 3181 RSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240 RSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG Sbjct: 3181 RSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240 Query: 3241 ERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPV 3300 ERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPV Sbjct: 3241 ERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPV 3300 Query: 3301 HEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAH 3360 HEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAH Sbjct: 3301 HEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAH 3360 Query: 3361 GLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPF 3420 GLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPF Sbjct: 3361 GLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPF 3420 Query: 3421 AFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPAL 3480 AFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPAL Sbjct: 3421 AFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPAL 3480 Query: 3481 LHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGD 3540 LHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGD Sbjct: 3481 LHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGD 3540 Query: 3541 CALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPG 3600 CALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPG Sbjct: 3541 CALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPG 3600 Query: 3601 ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAST 3660 ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAST Sbjct: 3601 ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAST 3660 Query: 3661 PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGS 3720 PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGS Sbjct: 3661 PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGS 3720 Query: 3721 QPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK 3780 QPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK Sbjct: 3721 QPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK 3780 Query: 3781 EKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQN 3840 EKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQN Sbjct: 3781 EKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQN 3840 Query: 3841 KPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAEAQ 3900 KPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAEAQ Sbjct: 3841 KPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAEAQ 3900 Query: 3901 SDLLSQLFGQRLTGFKIPLKKDASE 3925 SDLLSQLFGQRLTGFKIPLKKDASE Sbjct: 3901 SDLLSQLFGQRLTGFKIPLKKDASE 3925 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 143 bits (360), Expect = 4e-33 Identities = 273/1060 (25%), Positives = 359/1060 (33%), Gaps = 246/1060 (23%) Query: 6 PRGAPPPTMTGDLQPRQVASSPGHPSQP-----PLEDNTPATRTTKGAREAGGQAQAMEL 60 P+GAP P+ L P+ V P P P PAT K QA A+ + Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK-------QAPALSM 913 Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120 + P++AR P+ +G P+S P +G+P TPP +P PS G A SP Sbjct: 914 TSSSPKKAR----ATPAPKG-IPAS-PSPKGAP-TPPAATP---PSPKGGPATPSPKW-- 961 Query: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQ----GPGT----GAPLRPGL--PRTE 170 + T P+ P P + A P TP GP T GAP P + P + Sbjct: 962 -APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020 Query: 171 AQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQAS 230 PAA F + PP++ + SP+ATP P P T P G Sbjct: 1021 GSPAATP--FPKGASTPPAATPPSPKGSPAATPLPKG-APTTPAATLPSPKGGPATPSLK 1077 Query: 231 GADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF-- 288 GA + PPAA P P + P+P + P SP+G P GA T P Sbjct: 1078 GAPT-PPAATPPSPKGGPATPSPKGAPMPPAATP-PSPKG---GLATPPHKGAPTTPAAT 1132 Query: 289 -PADVAGHAF---TNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGG 344 P+ G A P A P P+ + T P PT PA +P GG Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPPPKGAPTTPAATP----PSPKGG 1185 Query: 345 LNRHSDLSGALSSPGAAHSAPR-PFSDSLHKSLTKILPERPPSAQDGL------GSTRGP 397 L S GA ++P A +P+ + K PPS + GL G+ P Sbjct: 1186 LATPSP-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244 Query: 398 PSSLPQRHFPGQAYRASGVDTSPG--PPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGP 455 ++ P G T P PP + PP P +P P+P GGP Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP---NPAVVTPPSPKGGP 1301 Query: 456 L------AATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEML-SRLPFPA 508 A T P P+ AP P P V P PSP G L + P Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP-PAVTP---PSPKGTPTLPATTPSSK 1357 Query: 509 GGPEWQGGSQGAL---------GTAGKTPGPREKLPAVRSSQGG--SPALF--------- 548 GGP +G G TP ++ PA+ S +G SPA+ Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417 Query: 549 -----------TYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP-------PRVVGASPSE 590 + +T P P+ A +P G P+ P P V SP E Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477 Query: 591 SPLP-----------SPATNT--AGSTCSSLSPMSSS--PANPSSEESQL---------- 625 P P +PAT T ++ P S PA PSS + Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537 Query: 626 -PGPLGPSAFFHPP--THPQETGSP-FPSPE-------------PPHSLPTHYQ--PEPA 666 P L P PP T P +P P+P+ PP P+ Y+ P P Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597 Query: 667 KAFPFPA--DGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASL 724 + PA E P P +GP +G P +PP P+ SL + Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP--ATPAPKGTPTSPPVTPS---SLKDSPT 1652 Query: 725 DQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL------PSPPA 778 V TC+ G + +A G GP L P+P + Sbjct: 1653 SPASV--TCKM------------------GATVPQASKGLPAKKGPTALKEVLVAPAPES 1692 Query: 779 APRVPADAHAG---LLSHAKTFLLAGDAQAE-GKDDPLRTGFLPSLAATPFPLPASDLDM 834 P + A G S A + + D A+ G PL T P PL D Sbjct: 1693 TPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST-------VAPAPLLPVQKDS 1745 Query: 835 EDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPE 894 AK G + A P GP P PE Sbjct: 1746 SKTAK----------GKD----------------ASHSPKGPLAP-------------PE 1766 Query: 895 SKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPT 934 SKA PL AA + P+P A P SL LAP+ Sbjct: 1767 SKASTPLTAAAFEKVLPKPESASVSAAPSPPV-SLPLAPS 1805 Score = 136 bits (342), Expect = 5e-31 Identities = 418/1845 (22%), Positives = 606/1845 (32%), Gaps = 321/1845 (17%) Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGA 1154 E EL Q P+ + P +A G P P P P P + P + Sbjct: 13 EQELPQ-PQAETAVLPMSSALSVTAALGQPG-PTLPPPCSPAPQQCPLS----------- 59 Query: 1155 AAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214 AA + P PS PL+VP FPQ + +AP++ F Sbjct: 60 AANQASP--FPSPSTIASTPLEVP--------------FPQSSSGTALPLGTAPEAPTFL 103 Query: 1215 EALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLA--NTAPHG--------- 1263 L PP + A ASP ++ P GTP S LA APH Sbjct: 104 PNLIGPPISPAALALASP-MIAPTL-------KGTPSSSAPLALVALAPHSVQKSSAFPP 155 Query: 1264 ---SSPTPGVGSLLGGPGGTQAPVSHNS-KDPPARQPGEFLAPVANPSSTACPKPSVLS- 1318 +SP + G AP++ + K + P E V NP T P P ++S Sbjct: 156 NLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEV---VPNPKGTPSP-PCIVST 211 Query: 1319 ------SKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHP 1372 + ++S A + +A PQ + S + + P++ L+ Sbjct: 212 VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271 Query: 1373 KPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLP 1432 P+A S + + AG P +PP P S L P Sbjct: 272 PPAALSLSTQSLPVVTSSQKTAG------PNTPPDF-----------PISLGSHLAP--- 311 Query: 1433 VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSD---------------PPYPSFLLLE 1477 +GS+ +G P A +DP KT+ D PP PS Sbjct: 312 ---LHQSSFGSVQLLGQTG-PSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPS---RN 364 Query: 1478 EVSPMLPSHFP------DLSGGKVLSKTCPPERTVVPGAAPSLPGKGSGCSVALMSHLSE 1531 EV P + FP D + S TC P ++ + SL + +L+ S Sbjct: 365 EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL-----SPTTSLILKSSP 419 Query: 1532 DELEIQKLVTELE-SQLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPH 1590 + LV ++ S + + P +A A + E+ T PP ++ P Sbjct: 420 NATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT-TFEVATCVSPP------MSSGPI 472 Query: 1591 EDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQED 1650 + + V A +E + VAT + P P P + Q+D Sbjct: 473 SNIEPTSPAALVMAPVAPKE-PSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKD 531 Query: 1651 L------VSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQ 1704 L + GAPFSP A K + L QA + P P P+ Sbjct: 532 LQTVPASLEGAPFSPAQAGL----TTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPE 587 Query: 1705 LDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPA 1764 +LAK S + L K ASS S L + A G Sbjct: 588 ---ATLAKKSLGEPLPIGK---PASSMTSP-----LGVNSSASVIKTDSYAGPDSAGPLL 636 Query: 1765 PEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGF 1824 + +P V A PL++ P G +P+ A G + T P Sbjct: 637 KSSLITPTV-----------AAFPLESADPAGVAPTTA--------KGTSTYTTTASPFL 677 Query: 1825 EGN-EFAPAG-----ASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPA---LSPPIR 1875 EG AP + T P LVP S C P A L+P I Sbjct: 678 EGTVSLAPKNHPVKEGTLTTLP------LVPTASENCPVAPSPQNTCAPLATLVLAPEIP 731 Query: 1876 QLQLPGPGV--------AKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPA 1927 + +P P + K DGI L P A SP K Sbjct: 732 K-SVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL 790 Query: 1928 QGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS-PGGTDN 1986 SP + V+ P + G +G A+ L PEN +S G D+ Sbjct: 791 ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL-PENSLSFQGSKDS 849 Query: 1987 HASVNA-SPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPS----------PPSP-N 2034 A+ ++ +P + PT AV KG ++L + PTPS P +P Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKG----VTLPPKETPTPSVVNLPFPKEGPATPAP 905 Query: 2035 RESLALALTAAHSRSGSEGRTPE--RASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSA 2092 +++ AL++T++ + P+ AS P P+P G PSP A Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG---PATPSPKWA 962 Query: 2093 AHMPCSLGPLPREDPLT------------SPSRAQGGLGGQLPASPSCRDPPGPQQLLAC 2140 P + P P+ P T +P +GG PA+PS + P P + Sbjct: 963 PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG-----PATPSPKGAPTPPAVTPP 1017 Query: 2141 SPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSW 2200 SP +P A+T PP+ T P PK + A L +G+P ++ Sbjct: 1018 SPKGSPAATPFPKGAST----------PPAAT--PPSPKGSPAATPLP-KGAPTTPAATL 1064 Query: 2201 P-PGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA-- 2257 P P A TP +T P + SP A PP A SP + Sbjct: 1065 PSPKGGPATPSLKGAPTPPAAT---PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121 Query: 2258 -TGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQA 2316 G +TP GL P P+ P P P+G + P +G Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP-SPKGGLATPPP--------KGAP 1172 Query: 2317 VTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDP--GTPETGRSGATKMPRVTCPSTG 2374 T T P G SP +G T + P P G GA P T PS Sbjct: 1173 TTPAATPPSPKGGLATPSP---KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229 Query: 2375 LGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQ 2434 GL T +P + + P +P+G P P +G PA+T Sbjct: 1230 GGLA-TPSPKGAPTTPAATPP---------SPKGGPATPP-----PKGAPTPPAATPPSL 1274 Query: 2435 WKGQA--PH--GPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLE- 2489 G A PH P V S + GP S K P P A PSP P P + Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG---APTPPAATPPSPKGSPGTPPPKG 1331 Query: 2490 -PLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPP 2548 P PP K P+ S+G P T P +G P + PP Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPS-SKGGP---TTPSSKEGPTPPAATPSHKGGPAMTPP 1387 Query: 2549 SPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRG 2608 SP P+ K P L PK+A +P EG + +G Sbjct: 1388 SPKRGPA---IPSPKGDPTSPAVIPLSPKKAPA-------------TPVTREGAATPSKG 1431 Query: 2609 KLRGRRLREESILPVSADVISDGRGSRPS-------PAMASYAASPSHCLSVEGGPEADG 2661 L + S+ A G + PS PA+ + + Sbjct: 1432 DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491 Query: 2662 EQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKG 2721 + P A +G + + + + A + + P + A L P Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA--PKEALI 1549 Query: 2722 ASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPE-TSSS 2780 A P++T A+ KE+ + P+ + + ++ P L P TS S Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609 Query: 2781 PADSTTSSCLQGLPDNPDTQGGVQGPEG-PT-PDASGSSAKDPPS 2823 P ++ T + P +P+ P+G PT P + SS KD P+ Sbjct: 1610 PKEAPTPPAV--TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652 Score = 131 bits (329), Expect = 2e-29 Identities = 351/1592 (22%), Positives = 528/1592 (33%), Gaps = 223/1592 (14%) Query: 1141 PQARGPSRSLE-TGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKE 1199 P + GP ++E T AA P PS L++P + P L P++ K Sbjct: 466 PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVS--------PPLPDPEDLKN 517 Query: 1200 -PETAEESAPDSTEFTEALRSPPAACAGE--MGASPGLLIPEQPPPSRHDTGTPKPSGSL 1256 P + P + L++ PA+ G A GL + P PK S S Sbjct: 518 LPSSVLVKFPTQKD----LQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSF 573 Query: 1257 ANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACP---- 1312 +T+ P +L G P+ + + A V S A P Sbjct: 574 QSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG 633 Query: 1313 ---KPSVLSSKISSFGCDPAGFNRDPLGV-PVAKKGPQPYSSPHSELFLGPKDLAGCFLE 1368 K S+++ +++F + A DP GV P KG Y++ S G LA Sbjct: 634 PLLKSSLITPTVAAFPLESA----DPAGVAPTTAKGTSTYTTTASPFLEGTVSLA----P 685 Query: 1369 ELHPKPSARDA-----PPASSSCLCQDGEDAGS-------LEPQLPRSPPGT----AETE 1412 + HP P AS +C L P++P+S P A T Sbjct: 686 KNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP 745 Query: 1413 PGRAASPPTLESSSLFPDLPVDRFDPP----------LYGSLSANRDSGLPFACA----- 1457 PG +S+L P + P G+L+ DS P + Sbjct: 746 PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQT 805 Query: 1458 -DPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCP----------PERTV 1506 PP K + P P L VSP+ S P+ S SK P P+ Sbjct: 806 KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865 Query: 1507 VPGAAPSLPGKG-----------SGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRG 1555 P A L KG S ++ Q + S + Sbjct: 866 TPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP 925 Query: 1556 APRELAEAESVGRVELGTGTEPPSQRRTCQATVPH---EDTFSAADLTRVGESTAHREGA 1612 AP+ + + S PPS + P + + G +T +GA Sbjct: 926 APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA 985 Query: 1613 ESA-VATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQK 1671 + AT + +G P P A P A+ P + + + PF P+GA+ P Sbjct: 986 PTPPAATPPSPKGGPATPSPKGAPTPP---AVTPPSPKGSPAATPF-PKGAST--PPAAT 1039 Query: 1672 AGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQ 1731 + K P PS + GP A K +P + P + + + Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGP---ATPSLKGAPTPPAATPPSPKGGPAT 1096 Query: 1732 ESEDSLRLLPCEQRGGFLPEPGTADQPHRGAP---------------APEAFGSPAVHLA 1776 S + P P+ G A PH+GAP P G+P A Sbjct: 1097 PSPKGAPMPPAATPPS--PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154 Query: 1777 PDLAFQGDGA--PPLDA-TWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAG 1833 + +G A PP A T P PS + G P A P +G P+ Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214 Query: 1834 ASSLTAPRGREAWLVPVPSP-ACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGIL 1892 + T P PSP ++ P PA +PP + GP K Sbjct: 1215 KGAPTTPAATP------PSPKGGLATPSPKGAPTTPAATPPSPK---GGPATPPPK---- 1261 Query: 1893 GLQELTPAAQSPPRVNPSGLEGG-TVEGGKVACGPA---QGSPGGVQVTTLPAVAGHQLG 1948 A +PP P L+GG K A PA SP G T+ P A Sbjct: 1262 -------GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314 Query: 1949 LEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLL 2008 G G +G T + P SP GT + S K T P+ Sbjct: 1315 ATPPSPKGSPG-TPPPKGAPTPPAVTPP---SPKGTPTLPATTPSSKGGPTTPS------ 1364 Query: 2009 EKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPL 2068 K + A + + P +PPSP R + + +P++A + + + Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424 Query: 2069 LATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSC 2128 AT PS GDL A +P S P + P+ P T S+ L P SP Sbjct: 1425 AAT-----PSKGDLTPPAVTPVSLKKAPAT--SAPKGGPATPSSKGDPTLPAVTPPSP-- 1475 Query: 2129 RDPPGPQQL-LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLL 2187 ++PP P+Q+ + SP AP A T SP P+ +S DP A L Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535 Query: 2188 QGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAG 2247 + + L + P A+T TP T ++ S A+SPP Sbjct: 1536 KKTPATLAPKEALIP---PAMTVPSPKKTPAIPT------PKEAPATPSSKEASSPP--- 1583 Query: 2248 AVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTA 2307 AV+PS P+ E + P P+ PP P +G ++ +P T Sbjct: 1584 AVTPST------YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637 Query: 2308 RLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPR 2367 T+ P P +L+ + P SPA + +MG + + G P + G T + Sbjct: 1638 ----------TSPPVTPSSLKDS-PTSPASVTCKMGATVPQ-ASKGLP--AKKGPTALKE 1683 Query: 2368 VTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS--RGYKK 2425 V TAP+ + S S + + GP + +K Sbjct: 1684 VLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQK 1743 Query: 2426 KPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQ 2485 + T G+ +P GP+ AS L+ K P P + + + + P Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPESKAS----TPLTAAAFEKVLPKPESASVSAAPSPPVS 1799 Query: 2486 QPLEPLAQKCQPPRKKSHRVS--------GKERPNHSRGDPSHVTQPPPAQGS---KEVL 2534 PL P PP+++ S K + + P P G + VL Sbjct: 1800 LPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVL 1859 Query: 2535 RAPGSPHSQQLHPPSPTEHEVDVK----------TPASKPRPDQAREDELHPKQAEKREG 2584 +P S + P+P+ + K + S P ++ + +QA+ Sbjct: 1860 VNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAA 1919 Query: 2585 RRWRREPTVDS-PSHSEGKSNKKRGKLRGRRL 2615 EP + S SE K+ K KL R++ Sbjct: 1920 AEIDEEPVSKAKQSRSEKKARKAMSKLGLRQV 1951 Score = 114 bits (286), Expect = 1e-24 Identities = 378/1660 (22%), Positives = 554/1660 (33%), Gaps = 313/1660 (18%) Query: 1135 PGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFP 1194 P P R+ + A + + GP + +P L V T+ S T L Sbjct: 359 PLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLIL--- 415 Query: 1195 QEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQP------PPSRHDTG 1248 +S+P++T + P + +G +P L+ P P + + Sbjct: 416 ----------KSSPNATYHYPLVAQMPVS---SVGTTP--LVVTNPCTIAAAPTTTFEVA 460 Query: 1249 T----PKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVA 1304 T P SG ++N P +SP V APV+ K+P + PV+ Sbjct: 461 TCVSPPMSSGPISNIEP--TSPAALV----------MAPVA--PKEPSTQVATTLRIPVS 506 Query: 1305 NPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAG 1364 P ++ SS + F +D VP + +G P+S + L KD Sbjct: 507 PPLPDPEDLKNLPSSVLVKFPTQ-----KDLQTVPASLEGA-PFSPAQAGLTT-KKDPTV 559 Query: 1365 CFLEELHPKPSARDAPPASSSCLCQDGEDA---GSLEPQLPRSPPGTAETEP-------- 1413 L + PK S +SS + E SL LP P ++ T P Sbjct: 560 LPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSAS 619 Query: 1414 --------GRAASPPTLESSSLFPDL---PVDRFDPPLYGSLSANRDSGLPFACADPPQK 1462 G ++ P L+SS + P + P++ DP +A S + + Sbjct: 620 VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679 Query: 1463 TV---PSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGA-------AP 1512 TV P + P L P++P+ + TC P T+V +P Sbjct: 680 TVSLAPKNHPVKEGTLT--TLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737 Query: 1513 SLPGKGSGCSVALMSHLSEDEL------EIQKLVTELESQLQRSKDTRGAPRELAEAESV 1566 SLP G+ + +S ++ TE +S + ++G LA++ S Sbjct: 738 SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE-DSGASATASSKGTLTYLADSPS- 795 Query: 1567 GRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRP 1626 LG P ++R P SA T +G ++ E++ ++ + Sbjct: 796 ---PLGVSVSPQTKR-------PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ- 844 Query: 1627 GGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDS 1686 G+ PA+ H S P SP+GA P S G+ ++ Sbjct: 845 -GSKDSPATTH---------------SPTPPSPKGAP---TPSAVTPLSPKGVTLPPKET 885 Query: 1687 RPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRG 1746 P V LP P + GP A PK A S S P + R Sbjct: 886 PTPSVVNLPFPKE--GPATPA--------------PKQAPALSMTSSS------PKKARA 923 Query: 1747 GFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGH 1806 P+ A +GAP P A P+ P +P T P PS Sbjct: 924 TPAPKGIPASPSPKGAPTPPAATPPSPKGGP-----ATPSPKWAPTPPAATPPSPKGGPA 978 Query: 1807 SAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQ 1866 + G P A P +G P+ + T P A P P + + P S Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP----AVTPPSPKGSPAATPFPKGAST 1034 Query: 1867 DPALSPPIRQ-----------------LQLPGPGVAKSKDGILGLQELTPAAQSPPRVNP 1909 PA +PP + LP P + + G TP A +PP +P Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP--TPPAATPP--SP 1090 Query: 1910 SGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGT 1969 G GPA SP G + + GL H G A T Sbjct: 1091 KG-------------GPATPSPKGAPMPPAATPPSPKGGLATPPHKG----APTTPA--- 1130 Query: 1970 ANQLQPENGVSP----GGTDNHASVNASPKTALT------GPTEGAVLLEKCKGSRAAMS 2019 A P+ G++ G A+ SPK L PT A KG A S Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190 Query: 2020 LQ-EEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPS 2078 + P +PPSP + +G A++P K LAT SP + Sbjct: 1191 PKGAPTTPAATPPSPK---------GGLATPSPKGAPTTPAATPPSPKGGLAT-PSPKGA 1240 Query: 2079 VGDLAACAPSPTSAAHMPCSLG-PLPREDPLTSPSRAQGGLGG---QLPASPSCRDPPGP 2134 AA PSP P G P P P +P +GGL + +P+ PP P Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTP---PAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297 Query: 2135 QQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSL------TTSPCDPK--EALAGCL 2186 + PA +P + A A T + SP PP +P PK L Sbjct: 1298 KG----GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353 Query: 2187 LQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP--- 2243 +G P PSS + A T +H G + P R + G TSP Sbjct: 1354 PSSKGGPTT-PSSKEGPTPPAATPSHKGGP----AMTPPSPKRGPAIPSPKGDPTSPAVI 1408 Query: 2244 PLAGAVSPSVAVRATGLSSTPTGD---------------EAQAGRGLPGPDPQSRGAP-- 2286 PL+ +P+ V G ++ GD A +G P P S+G P Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT-PSSKGDPTL 1467 Query: 2287 PHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSS 2346 P P P +P A + T P PTL P SP E+ + Sbjct: 1468 PAVTP---PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK----EVPATP 1520 Query: 2347 KEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTP 2406 DP P T + K P P L P+ T P + + TP Sbjct: 1521 SSRRDPIAP-TATLLSKKTPATLAPKEAL-----IPPAMTV-------PSPKKTPAIPTP 1567 Query: 2407 QGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARK 2466 + P P + S P + +KG AP P + A P + Sbjct: 1568 KEAPATPSSKEASS------PPAVTPSTYKG-AP-SPKELLIPPAVTSPSPKEAPTPPAV 1619 Query: 2467 HRPHPG-APAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVS-GKERPNHSRGDPSHVTQP 2524 P P PA P+P P P+ P + K P S G P S+G P+ + Sbjct: 1620 TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK--KG 1677 Query: 2525 PPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPR-PDQAREDELHPKQAEKRE 2583 P A KEVL AP + + P+ + + S P PD + K K Sbjct: 1678 PTAL--KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA------KNGSKGP 1729 Query: 2584 GRRWRREPTV----DSPSHSEGK--SNKKRGKLRGRRLREESILPVSADVISDGRGSRPS 2637 P + DS ++GK S+ +G L + + L +A P Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF-----EKVLPK 1784 Query: 2638 PAMASYAASPSHCLSVEGGPEADGEQPPRLATL--GPGVM 2675 P AS +A+PS +S+ P PP+ L PG++ Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLV 1824 Score = 113 bits (282), Expect = 4e-24 Identities = 392/1692 (23%), Positives = 563/1692 (33%), Gaps = 372/1692 (21%) Query: 22 QVASSPGHPSQPPLED-----NTPATRTTKGAREAGGQAQAMELPEA--QPRQARDGELK 74 QVA++ P PPL D N P++ K + Q L A P QA K Sbjct: 496 QVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKK 555 Query: 75 PPS---LRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKP 131 P+ L AP ++P + + +P PL + LA ++ G P I ASS T P Sbjct: 556 DPTVLPLVQAAPKNSPSFQSTSSSP--EIPLSPEATLAKKSLGEPLP--IGKPASSMTSP 611 Query: 132 TLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG---LPRTEAQP--AAEELGFHRCFQE 186 + +A + + D+ GP + PL P A P +A+ G + Sbjct: 612 LGVNS-------SASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAK 664 Query: 187 PPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP--PAAENSF- 243 S++T+T T P GT P + +++ P P+ +N+ Sbjct: 665 GTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLP-----LVPTASENCPVAPSPQNTCA 719 Query: 244 PGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLV 303 P A + P P+ +P P+L A T P V G + T+ Sbjct: 720 PLATLVLAPEIPKSVPS-----------------PSLPPAGTPPGTKKVDGISHTSA--- 759 Query: 304 FAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHS 363 P+ + P P + G + + G L+ Sbjct: 760 -------------------LAPVASSPKECPT-----EDSGASATASSKGTLTYLA---D 792 Query: 364 APRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPP 423 +P P S+ +RPP+ + + GP + + P AS + P Sbjct: 793 SPSPLGVSVSPQT-----KRPPTKK----GSAGPDTPIGNLSSPVSPVEASFL------P 837 Query: 424 DTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCL-PQSAPL 482 + L+ G + P PTPP G P+P L P+ L Sbjct: 838 ENSLSFQGSKDS-------PATTHSPTPPSP----------KGAPTPSAVTPLSPKGVTL 880 Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQG-ALGTAGKTPGPREKLPAVRSSQ 541 P P P+P + LPFP GP Q AL +P PA + Sbjct: 881 P-----PKETPTPS----VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK--- 928 Query: 542 GGSPALFTYNGM-TDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT 600 G PA + G T P A P SP G P+ P P+ P+ +P PSP Sbjct: 929 -GIPASPSPKGAPTPPAATP---------PSPKGGPATPSPKWAPTPPAATP-PSPKGGP 977 Query: 601 AG-STCSSLSPMSSSPANPSSEESQLPGPLG---PSAFFHPPTHPQETGSPFP--SPEPP 654 A S + +P +++P +P + P P G P A P +PFP + PP Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPAT-PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036 Query: 655 HSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP---PP 711 + P + PA A P P A P P GP L+G P P PP Sbjct: 1037 AATPPSPKGSPA-ATPLPKGAPTTPAA-----TLPSPKGGPATP--SLKGAPTPPAATPP 1088 Query: 712 YPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKD-----GHQR 766 P + S + T S LA G A G Sbjct: 1089 SPKGGPATPSPKGAPMPPAATP-------PSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141 Query: 767 SPGPPGLPSPPAAPRVPADAHAGLLSHAK-----TFLLAGDAQAEGKDDPLRTGFLPSLA 821 +P P G P+ PAA P GL + T + G P G + A Sbjct: 1142 TPPPKGAPTTPAA--TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199 Query: 822 ATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSS 881 ATP P P L A P G + Sbjct: 1200 ATP-PSPKGGL------------------------------------ATPSPKGAPTTPA 1222 Query: 882 GHPLKSKAGV-TPESKAPPPLPAATPD-----PQTPRPGDRGCPARGRPKTRSLGLA-PT 934 P K G+ TP K P PAATP P TP P P P + GLA P Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282 Query: 935 EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP-R 993 AP+ + GG A G + P G PP Sbjct: 1283 HKGAPNPA----------VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332 Query: 994 PRRPRTQAPGSRADPA-PRVPRAAALPEETRSSRRRRLPPRKDPRKRKA---------RG 1043 P P P + P P ++ T SS+ PP P + RG Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392 Query: 1044 -------GAWGKELILKIVQQK---NRLREYDFASESEEDEQPPP-------RGPGFRGR 1086 G ++ + +K + A+ S+ D PP + P Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452 Query: 1087 RG-------RGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGR 1139 +G +G+ P+E P P++ A + APA P P G+ P Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKE--PPAPKQVATSSSPKK-APATPA-PMGAPTLPAV 1508 Query: 1140 SPQARGPSRSLETGAAAREGGPKCADRPS------VAPKDPLQVPTNTETSEETRPSLDF 1193 P + P T ++ R+ A S +APK+ L P T S + P++ Sbjct: 1509 IPSS--PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566 Query: 1194 PQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPG---LLIPEQPPPSRHDTGTP 1250 P+EA +++E++ SPPA +P LLIP Sbjct: 1567 PKEAPATPSSKEAS-----------SPPAVTPSTYKGAPSPKELLIP---------PAVT 1606 Query: 1251 KPSGSLANTAPHGSSPTPGVGSLLGGPGG--TQAPVSHNS-KDPPARQPG-----EFLAP 1302 PS A T P + P+P G P G T PV+ +S KD P P Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666 Query: 1303 VANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGP--- 1359 A+ A P+ L + + PA P+ +KGPQ S + + P Sbjct: 1667 QASKGLPAKKGPTALKEVLVA----PAP-ESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721 Query: 1360 -KDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAAS 1418 K+ + L + P P P S G+DA S P+ P +PP + + P AA+ Sbjct: 1722 AKNGSKGPLSTVAPAPL---LPVQKDSSKTAKGKDA-SHSPKGPLAPPESKASTPLTAAA 1777 Query: 1419 ------PPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDP---- 1468 P S S P PV PL S P P Q+ +PS P Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSL---PLAPS---------PVPTLPPKQQFLPSSPGLVL 1825 Query: 1469 PYPSFLLL----EEVSPMLPSHFPDLSGG----KVLSKTCPPERTVVPGAAPSLP----- 1515 PS L +E+ P++P +SGG VL P+ +P PS Sbjct: 1826 ESPSKPLAPADEDELLPLIPPE--PISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTK 1883 Query: 1516 -GKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELGTG 1574 KGSG E + + V ELE Q T+ A +LA A + + Sbjct: 1884 NNKGSG-----------TESDSDESVPELEEQDSTQATTQQA--QLAAAAEIDEEPVSKA 1930 Query: 1575 TEPPSQRRTCQA 1586 + S+++ +A Sbjct: 1931 KQSRSEKKARKA 1942 Score = 111 bits (278), Expect = 1e-23 Identities = 285/1249 (22%), Positives = 415/1249 (33%), Gaps = 264/1249 (21%) Query: 1633 PASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKT----GLCQAEGDSRP 1688 PA PG + + ++ SP+ P + +GAS T G DS Sbjct: 741 PAGTPPGTKKVDGISHTSALAPVASSPKEC-----PTEDSGASATASSKGTLTYLADSPS 795 Query: 1689 PQDVCLPEPSKQP-------GPQLDAGSLAKCSPDQELSF-PKNKEAASSQESEDSLRLL 1740 P V + +K+P GP G+L+ E SF P+N + S Q S+DS Sbjct: 796 PLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPEN--SLSFQGSKDS---- 849 Query: 1741 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS 1800 P P P +GAP P A L+ +G PP + P + Sbjct: 850 PATTHSPTPPSP-------KGAPTPSA--------VTPLSPKGVTLPPKETPTPSVVNLP 894 Query: 1801 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860 +G P + APA + + ++P+ A P PA S Sbjct: 895 FPKEG----------------PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS--- 935 Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920 P PA +PP + GP K TP A +PP +P G Sbjct: 936 PKGAPTPPAATPPSPK---GGPATPSPK------WAPTPPAATPP--SPKG--------- 975 Query: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS 1980 GPA SP G T PA A P+ G + Sbjct: 976 ----GPATPSPKGAP--TPPA----------------------------ATPPSPKGGPA 1001 Query: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAE--PTPSPPSPNRESL 2038 SPK A PT AV KGS AA + A P +PPSP Sbjct: 1002 ----------TPSPKGA---PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048 Query: 2039 ALAL------TAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSA 2092 A L T A + +G P S G P AT P+P G PSP A Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGG-PATPSLKGAPTPPAAT--PPSPKGGP---ATPSPKGA 1102 Query: 2093 AHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADG 2152 P + P P+ T P + P SP P + +PA P G Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162 Query: 2153 VQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTH 2212 + GA +P A +P PK LA +G+P P++ PP + Sbjct: 1163 LATPPPKGAPTTPAA------TPPSPKGGLA--TPSPKGAP-TTPAATPPSPKGGLATPS 1213 Query: 2213 SGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAG 2272 P +P P G +PS G +TP Sbjct: 1214 PKGAP-----------------TTPAATPPSPKGGLATPS----PKGAPTTPAATPPSPK 1252 Query: 2273 RGLPGPDPQSRGAPPHTNPDRMPRG-----HSSYSPSNTARLGHREGQAVTAVPTEPPTL 2327 G P P+ PP P + G H +G T+ P PT Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312 Query: 2328 QGAGPDSPACLEGEMGTSSKE--PEDPGTPETGRSGATKMPRVT-----CPSTGLGLGRT 2380 A P SP +G GT + P P G +P T P+T Sbjct: 1313 PAATPPSP---KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369 Query: 2381 TAPSSTASDFQSDS---PQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKG 2437 T P++T S + P R + +P+GDP P + KK PA+ + Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP---KKAPATPVTREGAA 1426 Query: 2438 QAPHGPVT-CEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQ 2496 G +T V S + P S K G PA PS P + P + K + Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPK--------GGPATPSSKGDPTLPAVTPPSPK-E 1477 Query: 2497 PPRKKSHRVSGKERPNHSRGDPSHVTQPP-PAQGSKEVLRAPGSPHSQQLHPPSPTEHEV 2555 PP K +V+ P + P+ + P PA P +P S++ P +PT + Sbjct: 1478 PPAPK--QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR-DPIAPTATLL 1534 Query: 2556 DVKTPAS-KPR----------PDQAREDEL-HPKQAEKREGRRWRREPTVDSPSHSEGKS 2603 KTPA+ P+ P + + PK+A + P +PS +G Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP 1594 Query: 2604 NKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQ 2663 + K E ++P + V S P+P A +P S E GP + Sbjct: 1595 SPK-----------ELLIPPA--VTSPSPKEAPTPP----AVTPP---SPEKGPATPAPK 1634 Query: 2664 -PPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGE-----QPT 2717 P + P ++ + + C + GA P + L P + AL E P Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTC--KMGATVPQASKGL-PAKKGPTALKEVLVAPAPE 1691 Query: 2718 GQKGASARGFWGPRETKALG----VCKESGSE-------------PAEDSSRAHSRSEEG 2760 +A GP+ K+ +C + ++ P + S++ +G Sbjct: 1692 STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG 1751 Query: 2761 VWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGP 2809 + + P GPL PE+ +S T++ + + P++ P P Sbjct: 1752 K-DASHSPKGPLAPPESKAS--TPLTAAAFEKVLPKPESASVSAAPSPP 1797 Score = 108 bits (270), Expect = 1e-22 Identities = 177/710 (24%), Positives = 242/710 (34%), Gaps = 119/710 (16%) Query: 6 PRGAP------PPTMTGDLQPRQVASSPGHPSQ-PPLEDNTPATRTTKGAREAGGQAQAM 58 P+GAP PP+ G L +P P+ PP AT + KGA Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT------- 1220 Query: 59 ELPEAQPRQARDGELKPPSLRGQ--APSSTP-GKRGSPQTPPGRSPLQAPSRLAGRAEGS 115 P A P + G L PS +G P++TP +G P TPP P AP+ Sbjct: 1221 --PAATPPSPKGG-LATPSPKGAPTTPAATPPSPKGGPATPP---PKGAPT--------- 1265 Query: 116 PPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAA 175 PP + T P+L P + A P V TP P G P P+ P A Sbjct: 1266 PP---------AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP--PKGAPTPPA 1314 Query: 176 EELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ------A 229 PPS S P P PPA PP +GT P P + P + + Sbjct: 1315 AT---------PPSPKGSPGTPPPKGAPTPPAVTPPSPKGT-PTLPATTPSSKGGPTTPS 1364 Query: 230 SGADSWPPAAENSFPGANFGVPPAEPE----PIPKG--SRPGGSPRGVSFQFPFPALHGA 283 S PPAA S G PP+ P PKG + P P P Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424 Query: 284 STKPFPADVAGHAFTNGPL--VFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQ 341 + P D+ A T L A P+G + P P T P+P P + Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484 Query: 342 PGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSL 401 SSP A + P P ++ P+ P+ P ++L Sbjct: 1485 -----------ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533 Query: 402 PQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRS 461 + P + PP + +P PA +P + A P P A T S Sbjct: 1534 LSKKTPATLAPKEALI----PPAMTVPSPKKTPA-IPTPKEAPATPSSKEASSPPAVTPS 1588 Query: 462 MFFNGQPSPGQRLCLPQSAPLPWPQVLPTARP-SPHGMEMLSRLPFPAGGPEWQGGSQGA 520 + G PSP + L +P + P P+ PT +P E P P G P + + Sbjct: 1589 TY-KGAPSP-KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646 Query: 521 LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP 580 L + +P +V G + + G L + P +P TP + Sbjct: 1647 LKDSPTSPA------SVTCKMGATVPQASKGLPAKKGPTALKEVLVAP--APESTPIITA 1698 Query: 581 PRVVGASPSESPLPSP-------ATNTAGSTCSSLSPMSSSPANPSSEE-------SQLP 626 P G +S SP A N + S+++P P S + S P Sbjct: 1699 PTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP 1758 Query: 627 -GPLGP----------SAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEP 665 GPL P +A F E+ S +P PP SLP P P Sbjct: 1759 KGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVP 1808 Score = 89.7 bits (221), Expect = 5e-17 Identities = 295/1336 (22%), Positives = 419/1336 (31%), Gaps = 229/1336 (17%) Query: 899 PPLPAATPDPQTPRPGDRGCPARGRPKTRSL-GLAPTEADAPSQGRQQRRGKQLKLFRKD 957 P +P + P P P PA P T+ + G++ T A AP + + Sbjct: 728 PEIPKSVPSPSLP-------PAGTPPGTKKVDGISHTSALAPVASSPKECPTE------- 773 Query: 958 LDSGGAAEGSGSGG-GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADP------AP 1010 DSG +A S G A P LG P+ +RP T+ + D +P Sbjct: 774 -DSGASATASSKGTLTYLADSPSP-----LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827 Query: 1011 RVP-RAAALPEETRSSRRRRLPPRK--DPRKRKARGGAWGKELILKIVQQKNRLREYDFA 1067 P A+ LPE + S + + P P +G A + + + L + Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG-APTPSAVTPLSPKGVTLPPKETP 886 Query: 1068 SESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANP 1127 + S + P GP + Q P K AR G PA+P Sbjct: 887 TPSVVNLPFPKEGPATPAPK------------QAPALSMTSSSPKKARATPAPKGIPASP 934 Query: 1128 EEPGGSRPGPGRSPQARG----PS-RSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTE 1182 G P P +G PS + T AA PK + +PK P T Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK-GGPATPSPKGAPTPPAATP 993 Query: 1183 TSEETRPSLDFPQEAKEPET----AEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPE 1238 S + P+ P+ A P + + +P +T F + +PPAA Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT-------------- 1039 Query: 1239 QPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGE 1298 PPS P GS A T +PT +L GG P + PPA P Sbjct: 1040 --PPS--------PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089 Query: 1299 FLAPVANPSSTACPKPSVLSSKISSFGC---DPAGFNRDPLGVPVAKKG----PQPYSSP 1351 A PS P P + G G P P + KG P P +P Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149 Query: 1352 HSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAET 1411 + P G P P PA++ G L P+ P T Sbjct: 1150 TTPAATPPSPKGGL----ATPPPKGAPTTPAAT-----PPSPKGGLATPSPKGAPTTPAA 1200 Query: 1412 EPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF--ACADPPQKTVPSDPP 1469 P S P P P G L+ G P A P K P+ PP Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259 Query: 1470 YPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPSLPGKGSGCSVALMSHL 1529 +P P L GG PP + A + P G Sbjct: 1260 PKGAPTPPAATP------PSLKGG----LATPPHKGAPNPAVVTPPSPKGG--------- 1300 Query: 1530 SEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVP 1589 + +GAP A + + GT PP T A P Sbjct: 1301 ------------------PATSPPKGAP--TPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340 Query: 1590 HE----DTFSAADLTRVGEST--AHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAAL 1643 T A + G T + +EG AT + +G P T P P Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT-PSHKGGPAMTPPSPK-----RGPA 1394 Query: 1644 LPCAQEDLVSGA--PFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQP 1701 +P + D S A P SP+ A PV + GA+ ++GD PP + S + Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKA--PATPVTREGAA----TPSKGDLTPP---AVTPVSLKK 1445 Query: 1702 GPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL--PCEQRGGFLPEPGTADQPH 1759 P A PK A S + + +L + P + + T+ P Sbjct: 1446 APATSA--------------PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491 Query: 1760 RGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGH--LHP 1817 + P G+P + + + A P P + + ++ A A + P Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551 Query: 1818 TAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQL 1877 P + P + P +EA P +P +T+ S L PP + Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP----STYKGAPSPKELLIPP--AV 1605 Query: 1878 QLPGPGVAKSKDGIL-GLQELTPAAQSP------PRVNPSGLEGGTVEGGKVACGPAQGS 1930 P P A + + E PA +P P V PS L+ V C Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665 Query: 1931 PGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASV 1990 P + LPA G E L+ A ++ TA + T Sbjct: 1666 PQASK--GLPAKKGPTALKEV-----LVAPAPESTPIITAPTRKGPQTKKSSATSPPICP 1718 Query: 1991 NASPKTALTGP---TEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHS 2047 + S K GP A LL K S ++ + P +P + LTAA Sbjct: 1719 DPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF 1778 Query: 2048 RS---GSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAP-SPTSAAHMPCS-LGPL 2102 E + A SP ++ PL SP P++ P SP P L P Sbjct: 1779 EKVLPKPESASVSAAPSPPVSLPL---APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835 Query: 2103 PRED--PLTSPSRAQGGLGGQ-----LPA---------SPSCRDP-----PGPQQLLACS 2141 ++ PL P GG+ Q +P +PS + P G Sbjct: 1836 DEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSD 1895 Query: 2142 PAWAPLEEADGVQATT 2157 + LEE D QATT Sbjct: 1896 ESVPELEEQDSTQATT 1911 Score = 87.0 bits (214), Expect = 3e-16 Identities = 375/1612 (23%), Positives = 528/1612 (32%), Gaps = 311/1612 (19%) Query: 65 PRQARDGELKPPSLRGQAPSSTPGKRGS------PQTP--PGRSPLQAPSRLAGRAEGSP 116 P + PP+L PS + GS P P P + + PS + +G+P Sbjct: 144 PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTP 203 Query: 117 PQRYIL----------------GIAS-SRTKPTLDETPENPQLEAAQLPEV-DTPQGPGT 158 I+ G+AS +T PT +PQ++ + V +PQ PG+ Sbjct: 204 SPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGS 263 Query: 159 GAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGT-- 216 + P P PAA L Q P TS+ T+ TP P P S G+ Sbjct: 264 LSLKGPVSP-----PAALSLST----QSLPV-VTSSQKTAGPNTP----PDFPISLGSHL 309 Query: 217 SPLQPGSYPEYQASGADSWPPA----------AENSFPGANFGVPPAEPEPIPKGSRPGG 266 +PL S+ Q G + P A ++S GA++ + P+P SR Sbjct: 310 APLHQSSFGSVQLLG-QTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLP--SRNEV 366 Query: 267 SPRGVSFQFPFPA---------LHGASTKPFPADVAGHAFTNGPLVF---------AFHQ 308 P V+ FP A + + P + +F+ P +H Sbjct: 367 VPATVA-AFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHY 425 Query: 309 PQGA-WPEEAVGTGPAYPL-PTQPAPSPLPCYQ-----GQPGGLNRHSDLSGALSSPGAA 361 P A P +VGT P P A +P ++ P S++ +SP A Sbjct: 426 PLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEP--TSPAAL 483 Query: 362 HSAP-RPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP 420 AP P S + T +P PP + PSS+ + FP Q D Sbjct: 484 VMAPVAPKEPSTQVATTLRIPVSPPLPDPE--DLKNLPSSVLVK-FPTQK------DLQT 534 Query: 421 GPPDTELAAPGPPPARLPQLWDPTAAPY--PTPPGGPLAATRSMFFNGQPSPGQRLCLPQ 478 P E A P A L DPT P P P + S SP L Sbjct: 535 VPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATL---- 590 Query: 479 SAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVR 538 A + LP +P+ S + P G S ++ GP P ++ Sbjct: 591 -AKKSLGEPLPIGKPA-------SSMTSPLGV-----NSSASVIKTDSYAGPDSAGPLLK 637 Query: 539 SSQ-GGSPALFTYNGMTDPGAQPL-------FFGVAQPQVSPHGTPSLPP---------- 580 SS + A F G P + A P + GT SL P Sbjct: 638 SSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLE--GTVSLAPKNHPVKEGTL 695 Query: 581 ---PRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHP 637 P V AS + PSP +TC+ L+ + +P P S +P P P A P Sbjct: 696 TTLPLVPTASENCPVAPSPQ-----NTCAPLATLVLAPEIPKS----VPSPSLPPAGTPP 746 Query: 638 PTHPQE----TGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP-- 691 T + T + P P PT A A ++G L ++P P Sbjct: 747 GTKKVDGISHTSALAPVASSPKECPTEDSGASATA--------SSKGTLTYLADSPSPLG 798 Query: 692 -HEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHR 750 P+ R + A P P + S + ++ A+FL Sbjct: 799 VSVSPQTKRPPTKK-GSAGPDTPIGNLSSPVSPVE------------------ASFLPEN 839 Query: 751 QFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDD 810 + G + SP P+PP+ P + LS L + Sbjct: 840 SL-------SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV-- 890 Query: 811 PLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFAD 870 + F ATP P A L M + + T A G+ S +P+ + Sbjct: 891 -VNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP-ASPSPKGAPTPPAATPP 948 Query: 871 EEPSGPRGPS--------SGHPLKSKAG-VTPESKAPPPLPAATPDPQTPRPGDRGCPAR 921 GP PS + P K G TP K P PAATP P +G PA Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP------PSPKGGPAT 1002 Query: 922 GRPKTRSLGLAPTEADAPSQGRQQRRGKQLKL-FRKDLDSGGAAEGSGSGGGGRASGL-R 979 PK APT P+ +G F K + AA G A+ L + Sbjct: 1003 PSPKG-----APT---PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054 Query: 980 PRRNDGLGERPPPR-----------PRRPRTQAPGSRADPAPRVPRAAAL-PEETRSSRR 1027 P P+ P P P + PA P+ A + P T S + Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114 Query: 1028 RRL--PPRKDPRKRKA------RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPR 1079 L PP K A +GG L K A + P P+ Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGG-------LATPPPKG-------APTTPAATPPSPK 1160 Query: 1080 GPGFRGRRGRGEKRKEVELTQGPR--------EDEPQKPRKAARQEAGG------DGAPA 1125 G G +G P+ + P P GG GAP Sbjct: 1161 G-GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219 Query: 1126 NPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSE 1185 P S G +P +G + + +GGP P AP P P + + Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP-ATPPPKGAPTPPAATPPSLKGGL 1278 Query: 1186 ETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRH 1245 T P P A + + P +T + +PPAA SPG PPP Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGP-ATSPPKGAPTPPAATPPSPKGSPG-----TPPPK-- 1330 Query: 1246 DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVAN 1305 G P P ++ +P G+ P + GG P S PPA P P Sbjct: 1331 --GAPTPP-AVTPPSPKGTPTLP--ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385 Query: 1306 PSSTACPK--PSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLA 1363 P S PK P++ S K PA P P + ++P S+ L P + Sbjct: 1386 PPS---PKRGPAIPSPK--GDPTSPAVIPLSPKKAPATPVTREGAATP-SKGDLTPPAVT 1439 Query: 1364 GCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPP-----GTAETEPGRAAS 1418 L++ P SA PA+ S + ++ P P+ PP T+ + A+ Sbjct: 1440 PVSLKKA-PATSAPKGGPATPS--SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496 Query: 1419 P-----PTL-----ESSSLFPDLPVDRFDP--PLYGSLSANRDSGL-PFACADPPQKTVP 1465 P PTL S P P R DP P LS + L P PP TVP Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556 Query: 1466 SDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTC----PPERTVVPGAAPS 1513 S P+ +E +P PS S V T P+ ++P A S Sbjct: 1557 SPKKTPAIPTPKE-APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607 Score = 84.7 bits (208), Expect = 2e-15 Identities = 239/1058 (22%), Positives = 354/1058 (33%), Gaps = 162/1058 (15%) Query: 1961 AEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKC--KGSRAAM 2018 A+K+ G+ + SP G ++ ASV + A GP LL+ + AA Sbjct: 591 AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA--GPDSAGPLLKSSLITPTVAAF 648 Query: 2019 SLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPER---ASSPGLNKPLLATGDSP 2075 L E A+P P+ + + TA+ G+ P+ PL+ T Sbjct: 649 PL-ESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707 Query: 2076 APSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQ 2135 P APSP + P + L E P + PS P+ P PPG + Sbjct: 708 CP-------VAPSPQNTC-APLATLVLAPEIPKSVPS----------PSLPPAGTPPGTK 749 Query: 2136 QL--LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSP 2193 ++ ++ + A AP+ + T D+GA + + +LT P Q + P Sbjct: 750 KVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809 Query: 2194 LEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRK-EKLWESPGRA---TSPPLAGAV 2249 + S+ P + ++ S +P +++ +PE+S + +SP T P GA Sbjct: 810 TKKGSAGPDTPIGNLS---SPVSPVEASF-LPENSLSFQGSKDSPATTHSPTPPSPKGAP 865 Query: 2250 SPSVAVRAT--GLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPR-GHSSYSPSNT 2306 +PS + G++ P + LP P + P P + P +S SP Sbjct: 866 TPSAVTPLSPKGVTLPPKETPTPSVVNLPFP----KEGPATPAPKQAPALSMTSSSPKKA 921 Query: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMP 2366 +G + P PT A P SP + G ++ P+ TP + K Sbjct: 922 RATPAPKGIPASPSPKGAPTPPAATPPSP-----KGGPATPSPKWAPTPPAATPPSPKGG 976 Query: 2367 RVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTP---QGDPLGPQDLKQRSRGY 2423 T G P S + SP+ TP +G P K S Sbjct: 977 PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036 Query: 2424 KKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP 2483 P S + P G T AA+ S G + K P P A PSP P Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTP--AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094 Query: 2484 AQQPLE--PLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPH 2541 A + P+ PP K G P H + PP +G G+P Sbjct: 1095 ATPSPKGAPMPPAATPPSPKG----GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT 1150 Query: 2542 SQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEG 2601 + PPSP + + TP K P PK + +P+ Sbjct: 1151 TPAATPPSP---KGGLATPPPKGAPTTPAATPPSPKGGLATPSPK-------GAPTTPAA 1200 Query: 2602 KSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSP--AMASYAASPSHCLSVEGGPEA 2659 +G L + P + G + PSP A + AA+P P Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260 Query: 2660 DGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQ 2719 G P AT P ++G T GA P ++ P G P G Sbjct: 1261 KGAPTPPAAT--PPSLKGGLATPPHK------GAPNPA---VVTPPSPKGGPATSPPKGA 1309 Query: 2720 KGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSS 2779 A P+ + K + + PA TPP P G P + Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAV-----------------TPP-SPKGTP---T 1348 Query: 2780 SPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGG 2839 PA + +S +G P P ++ EGPTP A+ S K P+ + PP Sbjct: 1349 LPATTPSS---KGGPTTPSSK------EGPTPPAATPSHKGGPA----------MTPP-- 1387 Query: 2840 RLTRKRNPHV---YGKRCEKPVLPL-----PTQPSFEEG-GDPTLG----PARLPTDLSD 2886 + KR P + G V+PL P P EG P+ G PA P L Sbjct: 1388 --SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445 Query: 2887 SSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEP--SREAGAE 2944 + + P G P + G + +P + P +P EP ++ Sbjct: 1446 APA----------TSAPKGGPATPSSKG--DPTLPAVTPPSP------KEPPAPKQVATS 1487 Query: 2945 KLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSS 2982 P P P P L PA PA SS Sbjct: 1488 SSPKKAPATPAPMGAPTL---PAVIPSSPKEVPATPSS 1522 Score = 77.0 bits (188), Expect = 3e-13 Identities = 122/483 (25%), Positives = 154/483 (31%), Gaps = 66/483 (13%) Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLP 3478 PF G P A ++ + P K R P P P P+G+ + P Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS----PSPKGAP------TPP 943 Query: 3479 ALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGR 3538 A P + KG P T P T P P P P +P P A Sbjct: 944 A-------ATPPSPKGGPATPSPKWAP-TPPAATPPSPKGGPATPSPKGAPTPPAATP-- 993 Query: 3539 GDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRA 3598 P + P +P P GA P P +G A F Sbjct: 994 -----------PSPKGGPATPSPK-------GAPTP-PAVTPPSPKGSPAATPFPKGAST 1034 Query: 3599 PGARGRCAPDHFQEDHLLQKEKEVSSSHMVS--EGGPRGTFHKGSATKPAGCQSSSKDRS 3656 P A +P L K + + + +GGP KG+ T PA S K Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094 Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP-GTK 3715 A +P A P+ P S G LA G P TP A P G +P P G Sbjct: 1095 ATPSPKGA---PMPPAATPPS-PKGGLATPPHKGA-PTTPAATPPSPKGGLATPPPKGAP 1149 Query: 3716 TGGGSQPQPASGQLQSETATTPAK--PSFPSRSPAPERLPARAQAKSCTKGPREAGEQGP 3773 T + P G L AT P K P+ P+ +P P A KG P Sbjct: 1150 TTPAATPPSPKGGL----ATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATP 1202 Query: 3774 HGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTK 3833 P KG +T KG PA + G A +P P TP + P Sbjct: 1203 -----PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257 Query: 3834 PKPNSQNKP---RPPPSEQRKAEPGHTQRKDR--LGKAFPQGRPLLRPPKRGTAVHGAEP 3888 P P P PP + A P H + + P+G P PPK A P Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317 Query: 3889 AEP 3891 P Sbjct: 1318 PSP 1320 Score = 71.6 bits (174), Expect = 1e-11 Identities = 109/462 (23%), Positives = 153/462 (33%), Gaps = 49/462 (10%) Query: 3453 GSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSE----VAPSTTKGWPETLERPVDPVTH 3508 G A P + P P ++P +G L H + V P + KG P T P T Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT-SPPKGAPTP 1312 Query: 3509 PIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALP 3568 P P PPP +P P A+ P ++ P +P P Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372 Query: 3569 LGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628 + G KR P + P +G D + K+ ++ + Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAI-------PSPKG----DPTSPAVIPLSPKKAPATPVT 1421 Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP----------VHPRKAVGSL 3678 EG T KG T PA S K A S P P V P Sbjct: 1422 REGA--ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479 Query: 3679 APGELARGTENGMKPATPKAKPGPSSQG--SGSPR--PGTKTGGGSQPQPASGQLQSETA 3734 AP ++A + PATP P+ SP+ P T + P + L +T Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539 Query: 3735 TT--PAKPSFPSRS--PAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRK 3790 T P + P P+P++ PA K P P KG S K Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599 Query: 3791 --KGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSR--VLPT--KPKPNS------ 3838 V P+ E+ P +P+K P TP + TP+ V P+ K P S Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659 Query: 3839 -QNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKR 3879 P S+ A+ G T K+ L P+ P++ P R Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701 Score = 68.2 bits (165), Expect = 2e-10 Identities = 180/753 (23%), Positives = 241/753 (32%), Gaps = 131/753 (17%) Query: 3206 PAPKHHRGKRSAGKAAGSPG-DPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264 PAPK S A P P +G SP P A + PS G ATP Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP---- 980 Query: 3265 ATALADAGSPGPPRTTPSPSPDPWAG-GEPLLQATPVHEACKDPSRDCHHCGKRFPKPFK 3323 + G+P PP TP P P G P + P A PS FPK Sbjct: 981 ----SPKGAPTPPAATP---PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033 Query: 3324 LQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLYACELCATVM 3383 SP+ P+ P A L G P L+ P + Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPT--TPAATLPSPKGGPATPSLKGAPTPPAATPPSP- 1090 Query: 3384 RIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGA---PGQKARALEG 3440 +GG + +G P A P K Sbjct: 1091 ------------------------------KGGPATPSPKGAPMPPAATPPSPKGGL--A 1118 Query: 3441 TLPSKRRRVAMPGSAPGP--GEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPET 3498 T P K + P P G PPP+G +P + P+ +A KG P T Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPPSPK---GGLATPPPKGAPTT 1174 Query: 3499 LERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGS 3558 P P G PS + P + + P + G + GA P A+P S Sbjct: 1175 ---PAATPPSPKGGLATPS--PKGAPTTPAATPPSPKGGLATPSPKGAPTTP--AATPPS 1227 Query: 3559 PGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQK 3618 P L P GA P A +G A G P A P + Sbjct: 1228 PKGGLATPSPKGAP-TTPAATPPSPKGGPATPPPKGAPTPPAA----TPPSLKGGLATPP 1282 Query: 3619 EKEVSSSHMVS----EGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP--VHPR 3672 K + +V+ +GGP + KG+ T PA S K S + P K P V P Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG-SPGTPPPKGAPTPPAVTPP 1341 Query: 3673 KAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGG-SQPQPASGQLQS 3731 G+ ++ G P TP +K GP+ + P K G + P P G Sbjct: 1342 SPKGTPTLPATTPSSKGG--PTTPSSKEGPTPPAA---TPSHKGGPAMTPPSPKRG---- 1392 Query: 3732 ETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGP------------ 3779 PA PS +P +P + T RE G L P Sbjct: 1393 -----PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447 Query: 3780 ---KEKGESSTKRKKGQVPGPARSESVGSFGRAP------SAPDKPPRTPRKQATPS--R 3828 KG +T KG PA + AP S+P K P TP P+ Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507 Query: 3829 VLPTKPK-----PNSQNKP-RPPPSEQRKAEPGHTQRKDRL-----GKAFPQGRPLLRPP 3877 V+P+ PK P+S+ P P + K P K+ L P+ P + P Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567 Query: 3878 KRGTAVHGAEPAE------PHTHRTAEAQSDLL 3904 K A ++ A P T++ A + +LL Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600 Score = 67.8 bits (164), Expect = 2e-10 Identities = 104/442 (23%), Positives = 139/442 (31%), Gaps = 44/442 (9%) Query: 3464 PPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP 3523 P S + S L +L +P P+T +RP P G + P + P Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQT-KRP--PTKKGSAGPDTPIGNLSSP 827 Query: 3524 PPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA 3583 +SP A+ + G+ + P SP P P + P +++ +G Sbjct: 828 ---VSPVEASFLP-ENSLSFQGSKDSPATTHSPTPPSP---KGAPTPSAVTPLSPKGVTL 880 Query: 3584 EGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVS--EGGPRGTFHKGS 3641 K P P G P Q L + +G P KG+ Sbjct: 881 PPKETPTPSVVNLPFP-KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA 939 Query: 3642 ATKPAGCQSSSKDRSAASTPSKALKFPVH--PRKAVGSLAPGELARGTENGMKPATPKAK 3699 T PA S K A +P A P P G P T P +PK Sbjct: 940 PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG 999 Query: 3700 PGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAK-PSFPSRSPAPERLPARA-- 3756 P S G+P P T + PA+ +T PA P P SPA LP A Sbjct: 1000 PATPSP-KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058 Query: 3757 -------QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA 3809 K P G P + P KG +T KG PA + Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT--------- 1109 Query: 3810 PSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQ 3869 P +P TP + P+ T P P + PP + P T + G A P Sbjct: 1110 PPSPKGGLATPPHKGAPTTPAATPPSP--KGGLATPPPKGAPTTPAATPPSPKGGLATP- 1166 Query: 3870 GRPLLRPPKRGTAVHGAEPAEP 3891 PPK A P P Sbjct: 1167 ------PPKGAPTTPAATPPSP 1182 Score = 50.4 bits (119), Expect = 3e-05 Identities = 114/494 (23%), Positives = 165/494 (33%), Gaps = 74/494 (14%) Query: 3464 PPRGSSPILS-EGSLPALLHLCSEVAPSTTKGWPETLERPVDP-VTHPIRGCELPSN--- 3518 PP S PI + E + PA L + + TL PV P + P LPS+ Sbjct: 465 PPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLV 524 Query: 3519 ------HQECPPPSL-----SPFPAALADGRGDCALDGALERPEN----EASPGSPG-PL 3562 + P SL SP A L + L P+N +++ SP PL Sbjct: 525 KFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPL 584 Query: 3563 LQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDH---FQEDHLLQKE 3619 +A SL P G+ A +PL + PD + L+ Sbjct: 585 SPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPT 644 Query: 3620 KEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALK------FPVHPRK 3673 G T KG++T + + + + +K P+ P Sbjct: 645 VAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA 704 Query: 3674 A----VGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGG---------- 3719 + V A + P PK+ P PS +G+P PGTK G Sbjct: 705 SENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP-PGTKKVDGISHTSALAPV 763 Query: 3720 -SQPQ--PASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGS 3776 S P+ P S TA++ ++ + SP+P + Q K + P + G GP Sbjct: 764 ASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK---RPPTKKGSAGPDTP 820 Query: 3777 LGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQATPSRVLPTKPK 3835 +G S + P S S +P+ P P +P+ TPS V P PK Sbjct: 821 IGNLSSPVSPVEASF----LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876 Query: 3836 -----------PNSQNKPRP---PPSEQRKAEPGHTQRKDRLGKA----FPQGRPLLRPP 3877 P+ N P P P + K P + KA P+G P P Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936 Query: 3878 KRGTAVHGAEPAEP 3891 K A P P Sbjct: 937 KGAPTPPAATPPSP 950 Score = 50.4 bits (119), Expect = 3e-05 Identities = 142/634 (22%), Positives = 199/634 (31%), Gaps = 123/634 (19%) Query: 3245 PRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPD----PWAGGEPLLQAT-- 3298 P+ S P GA TP +A T + GSPG P +P+P P G P L AT Sbjct: 1297 PKGGPATSPPKGAPTPPAA--TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354 Query: 3299 -----PVHEACKD----PSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEH 3349 P + K+ P+ H G P +R A+ SP+ P P V P Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD---PTSPAVIP-- 1409 Query: 3350 GELLAHLGGAHGLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHM 3409 L + TP + ++ A S Sbjct: 1410 -------------LSPKKAPATP------------VTREGAATPS--------------- 1429 Query: 3410 NKHLRGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSS 3469 +G P A V AP A PS + +P P ++ P P+ + Sbjct: 1430 ----KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA 1485 Query: 3470 PILSEGSLPAL-----LHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPP 3524 S PA V PS+ K P T DP+ P Sbjct: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI---------------APT 1530 Query: 3525 PSL--SPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQD 3582 +L PA LA + + A+ P + +P P P A P P A Sbjct: 1531 ATLLSKKTPATLAP--KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA---- 1584 Query: 3583 AEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSA 3642 P + G AP + P + + + E GP KG+ Sbjct: 1585 ----VTPSTYKG---APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637 Query: 3643 TKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKP-- 3700 T P SS KD S S S K +A L + + + P++ P Sbjct: 1638 TSPPVTPSSLKD-SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696 Query: 3701 -GPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAK 3759 P+ +G P TK + P +A +K + +PAP LP + + Sbjct: 1697 TAPTRKG-----PQTKKSSATSPPIC----PDPSAKNGSKGPLSTVAPAP-LLPVQKDSS 1746 Query: 3760 SCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRT 3819 KG + P G L P E ++ST S APS P P Sbjct: 1747 KTAKG--KDASHSPKGPLAPPE-SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803 Query: 3820 PRKQAT---PSRVLPTKP--KPNSQNKPRPPPSE 3848 P T + LP+ P S +KP P E Sbjct: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837 Score = 42.7 bits (99), Expect = 0.007 Identities = 89/367 (24%), Positives = 129/367 (35%), Gaps = 48/367 (13%) Query: 321 GPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKIL 380 GP P P PAP P ++ + SP S P S T + Sbjct: 42 GPTLPPPCSPAPQQCPL---------SAANQASPFPSPSTIASTPLEVPFPQSSSGTALP 92 Query: 381 PERPPSAQDGLGSTRGPPSSLPQRHF--PGQAYRASGVDTSPGPPDTELAAPGPPPARLP 438 P A L + GPP S P A G +S P L A P + Sbjct: 93 LGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAP--LALVALAPHSVQKS 150 Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQP-SPGQRLCLPQSAPLPWPQVLPTARPSPHG 497 + P +PP +A + S+ P +P + P +V+P + +P Sbjct: 151 SAFPPNL--LTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVP---SEVVPNPKGTPSP 205 Query: 498 MEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL----PAVRSSQGGSPALFTYNGM 553 ++S +P+ P Q + + +T P L P V+ + S + N Sbjct: 206 PCIVSTVPYHCVTP--MASIQSGVASLPQTT-PTTTLAIASPQVKDTTISSVLISPQN-- 260 Query: 554 TDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSS 613 PG+ L V+ P T SLP V S ++ P+ + S S L+P+ Sbjct: 261 --PGSLSLKGPVSPPAALSLSTQSLP----VVTSSQKTAGPNTPPDFPISLGSHLAPLHQ 314 Query: 614 SPANPSSEESQLPGPLGPSAFFHPPTHP-----QETGSPFPSPE---PPHSLPTHYQPEP 665 S S QL G GPSA P TG+ +PS PP LP+ + P Sbjct: 315 S----SFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPP--LPSRNEVVP 368 Query: 666 AKAFPFP 672 A FP Sbjct: 369 ATVAAFP 375 Score = 38.5 bits (88), Expect = 0.13 Identities = 36/113 (31%), Positives = 45/113 (39%), Gaps = 8/113 (7%) Query: 3204 TEPAPKHHRGKRSAGKAAGSPG-DPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPD- 3261 T P+PK S A +P P +G SP A + PS G ATP Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237 Query: 3262 -SASATALADAGSP--GPPRTTPSPSPDPWAGGEPLLQ---ATPVHEACKDPS 3308 A T A SP GP P +P P A P L+ ATP H+ +P+ Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290 Score = 37.4 bits (85), Expect = 0.30 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 6/52 (11%) Query: 3233 EAKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPS 3284 + KDSP P TP +P GA TP ++ T L+ G PP+ TP+PS Sbjct: 844 QGSKDSPATTHSP----TPPSPKGAPTP--SAVTPLSPKGVTLPPKETPTPS 889 Score = 37.4 bits (85), Expect = 0.30 Identities = 31/105 (29%), Positives = 39/105 (37%), Gaps = 7/105 (6%) Query: 3204 TEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSA 3263 T P+PK G + G+P P + K SP P+ STP + S Sbjct: 992 TPPSPK---GGPATPSPKGAPTPP-AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047 Query: 3264 SATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPVHEACKDPS 3308 +AT L P T PSP P P L+ P A PS Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGP---ATPSLKGAPTPPAATPPS 1089 Score = 33.5 bits (75), Expect = 4.3 Identities = 43/149 (28%), Positives = 47/149 (31%), Gaps = 5/149 (3%) Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEG--EAKKDSPGE-RAKPRARSTPSNPDGAATPDS 3262 PAPK S KA +P P G SP E A P +R P P Sbjct: 1479 PAPKQVATSSSPKKAPATPA-PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537 Query: 3263 ASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCGKRFPKPF 3322 AT P T PSP P ATP + P K P P Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597 Query: 3323 KLQRHLAVHSPQRVYLCPRCPRVYPEHGE 3351 +L AV SP P P V P E Sbjct: 1598 ELLIPPAVTSPSPKE-APTPPAVTPPSPE 1625 Score = 33.1 bits (74), Expect = 5.6 Identities = 28/97 (28%), Positives = 36/97 (37%), Gaps = 2/97 (2%) Query: 3204 TEPAPKHHRGKRSAGKAAGSPG-DPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDS 3262 T P+PK S A P P +G SP P A + PS G ATP Sbjct: 946 TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005 Query: 3263 ASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299 A A +P P+ +P+ +P P P P Sbjct: 1006 KGAPT-PPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 115 bits (288), Expect = 9e-25 Identities = 266/1055 (25%), Positives = 337/1055 (31%), Gaps = 244/1055 (23%) Query: 8 GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATR-TTKGAREAGGQAQAMELPEAQPR 66 G P P M + R + G P P P T K A + P A+ R Sbjct: 170 GTPSPAMAR--RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227 Query: 67 QARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIAS 126 + G L+ P+ R + S+TP + P R +AP+ P Q G+ + Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH--------PSQPKPKGLQA 279 Query: 127 SR----TKPTLDETPENPQLEAAQLPEVDTPQGPGTGA-PLRPGLPRTEAQPAAEELGFH 181 R T P D P L ++ L TP GT A P+ P P A P L Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSGTKARPVPP--PDNAATPLPATL--- 331 Query: 182 RCFQEPPSSFTSTNYTSPSATP---RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPA 238 PPS P ATP PP+P P S T P P + P QA + + PP Sbjct: 332 -----PPSP--------PLATPLPLAPPSPSAPPSLQTLPSPPATPPS-QAPPSMTTPPM 377 Query: 239 AENSFPGANFGVPPAE-PEPIPKGS-RPGGSPRGVSFQFPFPALHGASTKPFPADVAGHA 296 P + +PP + P + S + SP +S +L ++ P A H+ Sbjct: 378 QA---PPSLQTIPPIQVPHSLTSPSLQAPPSPLALS------SLQATTSLGSPTLQATHS 428 Query: 297 FTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALS 356 F L + Q Q + T P+ P T P PL P + LS A+S Sbjct: 429 F----LTMSPRQTQASL------TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478 Query: 357 --------------SPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLP 402 S A+HS P S + L PPS Q S PP Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538 Query: 403 QRHFPGQAYRASGVDTSPG----------------------PPDTELAAPGPPPARLPQL 440 P AS T+P PP+T + PPP P L Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598 Query: 441 WDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEM 500 P P+PP PLA P L LP PL P PSP Sbjct: 599 ASPPLQGLPSPPLSPLATP-------PPQAPPXLALP---PLQAP-------PSPPASPP 641 Query: 501 LSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQP 560 LS L P+ P+ L A +P P P Q Sbjct: 642 LSPLATPS--PQAPNALAVHLLQAPFSPPP------------------------SPPVQA 675 Query: 561 LFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSS 620 F A P VSP TP P + A P + P PSP PA+P Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSP------------------PASPPM 716 Query: 621 EESQLPGPLGPSAFFHPPTH--PQETGSP--FPSPEPPHSLPTHYQPEPAKAFPFPADGL 676 S P P P PP P SP PS PP +P P + P P L Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776 Query: 677 GAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQC 736 + P P P + LQ P P +P SASL + Q Sbjct: 777 PMSPLAK-----PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 831 Query: 737 DRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKT 796 LAA L Q P PP P+ A R P +S + Sbjct: 832 P---PVLAAPLL----------------QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872 Query: 797 FLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSD 856 L A A G P P P+S L D A S T + Sbjct: 873 TL----ALAPGPPPP------------PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916 Query: 857 NPEIDSSF-----IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAAT------ 905 PE ++ ++ A + RGP+ + G AP P P AT Sbjct: 917 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG------APLPWPPATGPGSAD 970 Query: 906 ----------PDPQTPRPG--DRG-CPARGRPKTRSLGLAPTEADAPSQ--------GRQ 944 P+ TP PG D G P K + A + +P Q G Sbjct: 971 GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 1030 Query: 945 QRRGKQLKLFRKDL--DSGGAAEGSGSGGGGRASG 977 Q Q L R L + GAA GSG G GG G Sbjct: 1031 QASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 1065 Score = 103 bits (258), Expect = 3e-21 Identities = 277/1118 (24%), Positives = 361/1118 (32%), Gaps = 212/1118 (18%) Query: 144 AAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATP 203 AA+ P + TP+ PG+ P P P A LG P + + + Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPA-----ALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 204 RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSR 263 P GP +S GTS P S P ASG P A+N+ PG P + P +R Sbjct: 73 SAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAKNTSPG-----PVSSPGRASGTTR 125 Query: 264 PGG-SPRGVSFQFPFPALHGAST---KPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG 319 PG +G+ G +T K T+GP P A A G Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAG 184 Query: 320 TGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLS------GALSSPGAAHSAPRPFSDSLH 373 T P P P+ P P +G ++ S+ S A P A RP S SL Sbjct: 185 TEVGLPRPA-PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243 Query: 374 KSLTKI-LPERP-PSAQ--------------DGLGSTRGPPSSLPQRH-FPGQAYRASGV 416 S T + P R PSA+ GL + R P + P++ P +S Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303 Query: 417 DTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT--PPGGPLAATRSMFFNGQPSPGQRL 474 +P P T+ A P PPP D A P P PP PLA + PSP Sbjct: 304 LATPSPSGTK-ARPVPPP-------DNAATPLPATLPPSPPLATPLPL---APPSPSAPP 352 Query: 475 CLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL 534 L Q+ P P P P+ P + P P Q + P P Sbjct: 353 SL-QTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410 Query: 535 PAVRSSQGGSPAL---FTYNGMTDPGAQPLFFGVAQPQVSPHGTP------SLP--PPRV 583 ++ GSP L ++ M+ Q ++P +P +P SLP PP Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ 470 Query: 584 VGASPSESPLPSPATNTAGSTCSSL------SPMSSSPANPSSEESQLPGP---LGPSAF 634 SP+ SPL SP T SSL +P+SS P +S L P P++ Sbjct: 471 TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530 Query: 635 FHPPTH--------PQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLE 686 PP P +T S P P P P P +A P P E Sbjct: 531 TTPPLENLPSLAPPPLQTASA-PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI-- 587 Query: 687 ETPFPHEGPEVGRGGLQGFP-------RAPPPYPTHHFSL-------SSASLDQLDVLLT 732 TP P P + LQG P PPP +L S + L L T Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647 Query: 733 CRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLP-----SPPAAPRVPADAH 787 + ++LA L F SP PP P SPPA+P V A Sbjct: 648 --PSPQAPNALAVHLLQAPF--------------SP-PPSPPVQAPFSPPASPPVSPSA- 689 Query: 788 AGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEA 847 +QA PSLAA P +P S + + +A Sbjct: 690 ------------TPPSQAP-----------PSLAAPPLQVPPSPPASPPMSPSATPPPQA 726 Query: 848 LNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLK-SKAGVTPESKAPPPLPAATP 906 P + + + V S P PS+ P + P + PP PA+ P Sbjct: 727 ---------PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777 Query: 907 DPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEG 966 +P + PA P ++L P A P Q +A Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPP--ASFPGQA----------------PFSPSASL 819 Query: 967 SGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSR 1026 S P L + PP P P QAP R P P + + P T + Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP--RRPPTPGPDTSVSGPRLTLA-- 875 Query: 1027 RRRLPPRKDPRKRKARGGAWGKELI---LKIVQQKNRLREYDFASESEEDEQPPP----- 1078 P P R G +L LR YD E PPP Sbjct: 876 --LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 933 Query: 1079 --------RGP----GFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPAN 1126 RGP FRG G L P E +G + Sbjct: 934 ACHPAAWSRGPAPPLAFRGAPG-------APLPWPPATGPGSADGLCTIYET--EGPESA 984 Query: 1127 PEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCA 1164 PG PGP SP G + GA A PK A Sbjct: 985 TPAPGALDPGP--SPGTSGGKAAAGAGAGASSRSPKQA 1020 Score = 93.2 bits (230), Expect = 5e-18 Identities = 181/744 (24%), Positives = 241/744 (32%), Gaps = 122/744 (16%) Query: 3 GERPRGAPPPTMTGDLQPRQVASSPGHPSQPPL---EDNTPATRTTKGAREAGGQAQAME 59 G + R PPP P + SP + PL + P + T + A +QA Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370 Query: 60 LPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQR 119 P QA PPSL+ P P SP SPL S A + GSP + Sbjct: 371 SMTTPPMQA------PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424 Query: 120 Y---ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176 L ++ +T+ +L +P P P + P PL+ L P + Sbjct: 425 ATHSFLTMSPRQTQASLT-SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSS 482 Query: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236 L H P + +S SP A P PP +S L P P Q A Sbjct: 483 PLTIH-----PLQALSSLASHSPQA-PLSSLIMPPLETQSS-LAP---PSLQTPPASLTT 532 Query: 237 PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF---PADVA 293 P EN +P P P+ S P +P + P P A P P + Sbjct: 533 PPLEN--------LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584 Query: 294 GHAFTNGPLVF-AFHQPQGAWPEEAVGTGPAYPLPTQPAPSP----LPCYQGQPGGLNRH 348 T P A P P + + + P PL T P +P LP Q P Sbjct: 585 SSIATPPPQAPPALASP----PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP------ 634 Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPG 408 S + SP A S P + ++H P P Q PP S P P Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPS 693 Query: 409 QA---YRASGVDTSPGPPDTELAAPG--PPPARLPQLWDPTAAPYPTPPGGPLAATRSMF 463 QA A + P PP + +P PPP P L P P+PP P M Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-----PMS 748 Query: 464 FNGQPSP-------GQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGG 516 + P P L +P S P P + P A+P P L+ P A Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLP-MSPLAKPPPQAPPALATPPLQA-------- 799 Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG-VAQPQVSPHGT 575 P P P + + P A P+ + Q SP + Sbjct: 800 ----------LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849 Query: 576 PSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFF 635 P+L PR P P P T+ +G + P S S L GP Sbjct: 850 PTLQAPR-------RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902 Query: 636 HPPTHPQE--------TGSPFPSPEPPHSL--------------PTHYQPEPAKAFPF-P 672 + P+E G SP P L P ++ P P+ P Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962 Query: 673 ADGLGAEGAFQCLEETPFPHEGPE 696 A G G+ + ET EGPE Sbjct: 963 ATGPGSADGLCTIYET----EGPE 982 Score = 74.7 bits (182), Expect = 2e-12 Identities = 114/407 (28%), Positives = 137/407 (33%), Gaps = 59/407 (14%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-NTPATRTTKGAREAGGQA----- 55 P P PPP L + + P P+ PPL TP+ + QA Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668 Query: 56 -----QAMELPEAQP---RQARDGELKPPSLRG---QAPSSTPGKRGSPQTPPGRSPLQA 104 QA P A P A PPSL Q P S P P +P P QA Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQA 726 Query: 105 PSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRP 164 P LA PP AS P+ P P L AA P + P P P+ P Sbjct: 727 PPPLAAPPLQVPPS----PPASPPMSPSATPPPRVPPLLAA--PPLQVPPSPPASLPMSP 780 Query: 165 -GLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSAT------PRPPAPGPPQSRG-- 215 P +A PA + PP+SF SPSA+ PP PP Sbjct: 781 LAKPPPQAPPALATPPL-QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839 Query: 216 -TSPLQPGSYPEYQASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSF 273 P P + P QA P P S P + P P P P SP + Sbjct: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP------PSRSPSS-TL 892 Query: 274 QFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQ-----GAWPEEAVGTGPAYPL-- 326 P A H +S P ++ G + +GP A P A A GPA PL Sbjct: 893 SGPDLAGHSSSATSTPEELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950 Query: 327 ---PTQPAPSPLPCYQGQPGGLNRHSDLSG---ALSSPGAAHSAPRP 367 P P P P G GL + G A +PGA P P Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997 Score = 73.6 bits (179), Expect = 4e-12 Identities = 241/1046 (23%), Positives = 324/1046 (30%), Gaps = 191/1046 (18%) Query: 877 RGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQ--TPRPGDRGCPARGRPKTRSLGLAPT 934 R P+S P + P +K P P ++P T RPG G + L ++ Sbjct: 88 RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG--------QKGLRISAE 139 Query: 935 EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLG-ERPPPR 993 E A RGK + ++ S GA + G S RR+ G E PR Sbjct: 140 ETVA--------RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191 Query: 994 PRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILK 1053 P AP +R P PR + + +S P R+R + GG + Sbjct: 192 P------APSARPRPPTEGPRKSV----SSASEHSTTEPSPAARRRPSAGGGLQRP---- 237 Query: 1054 IVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKA 1113 AS S P P G RG R Sbjct: 238 -------------ASRSLSSSATPLSSPARSGPSARGTPR-------------------- 264 Query: 1114 ARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKD 1173 APA+P +P R PQ P + P PS Sbjct: 265 ---------APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315 Query: 1174 PLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPG 1233 P+ P N T P T S P +T A SP A + + SP Sbjct: 316 PVPPPDNAATPL--------------PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361 Query: 1234 LLIPEQPPPSR--------------------HDTGTPK----PS----GSLANTAPHGSS 1265 P Q PPS H +P PS SL T GS Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421 Query: 1266 PTPGVGSLLG-GPGGTQAPVSHNSK---DPPARQPGEFLAPVANPSSTACPKPSVLSSKI 1321 S L P TQA ++ S+ PP P AP++ P+S P + LS + Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP--LQAPLSLPASP--PLQTSLSPAV 477 Query: 1322 SSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFL-EELHPKPSARDAP 1380 S P + +A PQ +P S L + P + L P++ P Sbjct: 478 SPLS-SPLTIHPLQALSSLASHSPQ---APLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533 Query: 1381 P----ASSSCLCQDGEDAGSLEPQLPRSP---PGTAETEPGRAASPPTLESSSLF---PD 1430 P S + A P L P P + P +PP SS+ P Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593 Query: 1431 LPVDRFDPPLYG------SLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLP 1484 P PPL G S A P A PP + PS P P L SP P Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653 Query: 1485 SHFP-DLSGGKVLSKTCPP-ERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTE 1542 + L PP + P A+P + + S A S L+ L++ Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPA 712 Query: 1543 LESQLQRSKDTRGAPRELA------EAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSA 1596 + AP LA + PP + A P + S Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772 Query: 1597 ADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAP 1656 + A A+AT P P P + PG A P A + A Sbjct: 773 PASLPMSPLAKPPPQAPPALAT------PPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826 Query: 1657 FSPRGANFHFQPVQKAGASKTGLCQAEGDSRPP---QDVCLPEP----SKQPGPQLDAGS 1709 P+ P+ + S + RPP D + P + PGP Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886 Query: 1710 LAKCSPDQELSFPK-NKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAF 1768 SP LS P ++S+ + + LR GG P + PA + Sbjct: 887 ----SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 942 Query: 1769 GSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHA--------AQG-HSAGRAGGHLH--P 1817 G AP LAF+ GAP WP P A +G SA A G L P Sbjct: 943 GP-----APPLAFR--GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 995 Query: 1818 TAGRPGFEGNEFAPAGASSLTAPRGR 1843 + G G + A AGASS + + R Sbjct: 996 SPGTSGGKAAAGAGAGASSRSPKQAR 1021 Score = 71.2 bits (173), Expect = 2e-11 Identities = 269/1144 (23%), Positives = 371/1144 (32%), Gaps = 196/1144 (17%) Query: 1639 GHAALLPCAQED--LVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQ------ 1690 G AA P A+ L P SPR PV A G A G + Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPP----PPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 Query: 1691 DVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLP 1750 +PE + + GP AG+ ++ + + + + A ++ + Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTS---------------- 110 Query: 1751 EPGTADQPHR--GAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSA 1808 PG P R G P G + ++ + A +P +A SA Sbjct: 111 -PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE---------APKRSAL--SA 158 Query: 1809 GRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDP 1868 G PT G P + A + + PR P PS T R+S Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR-------PAPSARPRPPTEGPRKSVSS 211 Query: 1869 AL-------SPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGK 1921 A SP R+ G G+ + L TP + SP R PS GT + Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLS-SSATPLS-SPARSGPSAR--GTP---R 264 Query: 1922 VACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSP 1981 P+Q P G+Q P V + +A G L + + + +P Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRK--DAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322 Query: 1982 GGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALA 2041 T A++ SP A P A SLQ P +PPS S+ Sbjct: 323 AATPLPATLPPSPPLATPLPLAPP-------SPSAPPSLQTLPSPPATPPSQAPPSMTTP 375 Query: 2042 LTAAHS--RSGSEGRTPERASSPGLNKPLLATGDSPAP-SVGDLAACAP--SPT-SAAHM 2095 A ++ + P +SP L P P+P ++ L A SPT A H Sbjct: 376 PMQAPPSLQTIPPIQVPHSLTSPSLQAP-------PSPLALSSLQATTSLGSPTLQATHS 428 Query: 2096 PCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEE---ADG 2152 ++ P + LTSPSR P P P + SPA +PL Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488 Query: 2153 VQATTDTGAEDSPVAP-PSLTTSPCDPKEALAGCLLQGEGS-----PLED-PSSWPP--G 2203 +QA + A SP AP SL P + + +LA LQ + PLE+ PS PP Sbjct: 489 LQALSSL-ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547 Query: 2204 SVSAVTCTHSGDTP----------KDSTLRIPEDSRKEKLWESPGRA----TSPPLAGAV 2249 + SA T +TP S L P + P +A SPPL G Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607 Query: 2250 SPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRG------HSSYSP 2303 SP ++ AT P + P P +P T + P + +SP Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667 Query: 2304 SNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGAT 2363 + + QA + P PP A P S A P P +P S AT Sbjct: 668 PPSPPV-----QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-AT 721 Query: 2364 KMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGY 2423 P+ P L PS AS S S + P+ PL Q Sbjct: 722 PPPQAPPPLAAPPL--QVPPSPPASPPMSPS-------ATPPPRVPPLLAAPPLQVP--- 769 Query: 2424 KKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPS-PAAL 2482 PAS P P P L+ P A PS PA+ Sbjct: 770 PSPPASLPMSPLAKPPPQAP-------------PALAT---------PPLQALPSPPASF 807 Query: 2483 PAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHS 2542 P Q P P A P P + + Q PP+ + L+AP Sbjct: 808 PGQAPFSPSASLPMSP-------LATPPPQAPPVLAAPLLQVPPSPPASPTLQAP----- 855 Query: 2543 QQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGK 2602 PP+P T S PR A P R P D HS Sbjct: 856 --RRPPTP-----GPDTSVSGPRLTLALAP--GPPPPPSRSPSSTLSGP--DLAGHSSSA 904 Query: 2603 SNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGE 2662 ++ +LRG E S ++ P A+++ P+ L+ G P A Sbjct: 905 TSTPE-ELRGYDSGPEGGAAASPPPDAELAACHP----AAWSRGPAPPLAFRGAPGAPLP 959 Query: 2663 QPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQ-KG 2721 PP GPG +G + G A PG L PG G + G+ G G Sbjct: 960 WPP---ATGPGSADGLCTIYE---TEGPESATPAPG--ALDPGPSPGTSGGKAAAGAGAG 1011 Query: 2722 ASAR 2725 AS+R Sbjct: 1012 ASSR 1015 Score = 68.9 bits (167), Expect = 9e-11 Identities = 105/410 (25%), Positives = 137/410 (33%), Gaps = 79/410 (19%) Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSP--AP 2077 LQ P PSPP + + S S TP + P L P L SP +P Sbjct: 661 LQAPFSPPPSPP------VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714 Query: 2078 SVGDLAACAP-SPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQ 2136 + A P +P A P + P P P SPS L A+P + PP P Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774 Query: 2137 LLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLED 2196 L SP A+ P APP+L T P LQ SP Sbjct: 775 SLPMSPL-----------------AKPPPQAPPALATPP-----------LQALPSP--- 803 Query: 2197 PSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP--SVA 2254 P+S+P G P + +P ++P +P L SP S Sbjct: 804 PASFP------------GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851 Query: 2255 VRATGLSSTPTGDEAQAGRGL-----PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARL 2309 ++A TP D + +G L PGP P +P T GHSS + S L Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911 Query: 2310 -GHREGQAVTAVPTEPPTLQGA---------GPDSPACLEGEMGTSSKEP--EDPGTPE- 2356 G+ G A + PP + A GP P G G P PG+ + Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971 Query: 2357 -------TGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHR 2399 G AT P P G A + + S SP+ R Sbjct: 972 LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021 Score = 68.2 bits (165), Expect = 2e-10 Identities = 259/1167 (22%), Positives = 357/1167 (30%), Gaps = 201/1167 (17%) Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR---GPSRSL-ETGAAAREGGPKCA 1164 K AAR A P PG RP P +P A G + ++ A R GG A Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 Query: 1165 DRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAAC 1224 P AP+ PT + + P+ P + E AP + + S P Sbjct: 69 TIPESAPRAG---PTRSAGTSSRNPASRPPASGRG-----ERAPPAKNTSPGPVSSPGRA 120 Query: 1225 AGEMGASP----GLLIPEQPPPSRHD-TGTPKPSGSLANTAPHGSSPTPGVGS------- 1272 +G P GL I + +R T PK S A S PTPG S Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180 Query: 1273 -LLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGF 1331 G G P PP P + ++ + S+T +PS + + S G G Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT---EPSPAARRRPSAG---GGL 234 Query: 1332 NRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDG 1391 R P ++ P SSP PSAR P A + Sbjct: 235 QR-PASRSLSSSAT-PLSSP------------------ARSGPSARGTPRAPA------- 267 Query: 1392 EDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSG 1451 P P+ P G P + +PP +++ L P A R Sbjct: 268 ------HPSQPK-PKGLQALRPPQV-TPPRKDAAPALGPLSSSPLATPSPSGTKA-RPVP 318 Query: 1452 LPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDL-SGGKVLSKTCPPERTVVPGA 1510 P A P T+P PP + L L SP P L S PP T P Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378 Query: 1511 AP---------------------SLPGKGSGCSVALMSHLSEDELE-IQKLVTELESQLQ 1548 AP + P + S+ + L L+ +T Q Q Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438 Query: 1549 RSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAH 1608 S + P + L PP Q A P + L + +H Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498 Query: 1609 REGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQP 1668 A + + ++ + P S A+L E+L S AP P Sbjct: 499 SPQAPLSSLIMPPLETQSS---LAPPSLQTPPASLTTPPLENLPSLAP----------PP 545 Query: 1669 VQKAGAS------KTGLCQAEGD-SRPPQDVCLP---EPSKQPGPQLDAGSLAKCSPDQE 1718 +Q A A +T C A PP + P PS P A P Q Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605 Query: 1719 LSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPD 1778 L P A+ LP Q P + P+P+A + AVHL Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPP--SPPASPPLSPLATPSPQAPNALAVHLL-Q 662 Query: 1779 LAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLT 1838 F +PP+ A + ASP + +A P+ P + P AS Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQA----PPSLAAPPLQVPPSPP--ASPPM 716 Query: 1839 APRGREAWLVPVP---SPACVSNTHPSRRSQDPALSPPIR---QLQLPGPGVAKSKDGIL 1892 +P P P P V + P+ P+ +PP R L P V S L Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776 Query: 1893 GLQELT-PAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEA 1951 + L P Q+PP + L+ P PG + ++ L Sbjct: 777 PMSPLAKPPPQAPPALATPPLQ--------ALPSPPASFPGQAPFSPSASLPMSPLATPP 828 Query: 1952 DGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKC 2011 +L Q+ P SP P T+++GP Sbjct: 829 PQAPPVLA--------APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP---------- 870 Query: 2012 KGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLAT 2071 R ++L P P PP S L+ S S TPE + P Sbjct: 871 ---RLTLAL----APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD-SGPEGGA 922 Query: 2072 GDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDP 2131 SP P +LAAC P+ S GP P P +G G LP P+ Sbjct: 923 AASPPPD-AELAACHPAAWSR-------GPAP-------PLAFRGAPGAPLPWPPA---- 963 Query: 2132 PGPQQLLACSPAWAPLEEADGVQATTDT-GAEDSPVAPPSLTTSPCDPKEALAGCLLQGE 2190 GP ADG+ +T G E + AP +L P G Sbjct: 964 TGP-------------GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA 1010 Query: 2191 GSPLEDP-----SSWPPGSVSAVTCTH 2212 G+ P P G++ A H Sbjct: 1011 GASSRSPKQARLGELPLGALQASVVQH 1037 Score = 58.5 bits (140), Expect = 1e-07 Identities = 95/375 (25%), Positives = 137/375 (36%), Gaps = 76/375 (20%) Query: 3523 PPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALP-------LGASLPR 3575 PPP ++P + G +P E + G G + ++ P G S Sbjct: 35 PPPPVTPAALRVLGAAGAVG-----RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89 Query: 3576 PGARGQ-DAEGKRAPLVFSGKRRAPG---ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEG 3631 P +R G+RAP K +PG + GR A + L QK +S+ V+ Sbjct: 90 PASRPPASGRGERAP---PAKNTSPGPVSSPGR-ASGTTRPGPLGQKGLRISAEETVA-- 143 Query: 3632 GPRGTFHKGSATK-PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENG 3690 +G AT+ P S+ R S P+ P R++ A GTE G Sbjct: 144 -------RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS--------RAAGTEVG 188 Query: 3691 MKPATPKAKPGPSSQG------------SGSPRPGTK---TGGGSQPQPASGQLQSETAT 3735 + P A+P P ++G + P P + + GG +PAS L S Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248 Query: 3736 -------------TPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEK 3782 TP P+ PS+ P P+ L A + A GP S Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307 Query: 3783 GESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKP 3842 S TK + VP P ++ + A P P TP A PS P+ P P+ Q P Sbjct: 308 SPSGTKAR--PVPPP---DNAATPLPATLPPSPPLATPLPLAPPS---PSAP-PSLQTLP 358 Query: 3843 RPPPSEQRKAEPGHT 3857 PP + +A P T Sbjct: 359 SPPATPPSQAPPSMT 373 Score = 46.6 bits (109), Expect = 5e-04 Identities = 139/611 (22%), Positives = 190/611 (31%), Gaps = 117/611 (19%) Query: 428 AAPGPPPARLPQLWD--PTAAPYPTPPGGPLAATRSMFFNGQPSPGQR-----------L 474 AA P AR P L P +P P PP P AA R + G + G++ Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTP-AALRVLGAAG--AVGRKPLAERAGGIGGA 68 Query: 475 CLPQSAPLPWP-------QVLPTARPSPHGM-----EMLSRLPFPAGGPEWQGGS--QGA 520 +P+SAP P P +RP G + P P P G+ G Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128 Query: 521 LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTD-----PG-----------AQPLFFG 564 LG G E + ++++ + + D PG A G Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188 Query: 565 VAQPQVSPHGTPSLPPPR--VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEE 622 + +P S P PR V AS + PSPA S L +S + S+ Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248 Query: 623 SQLPGPLGPSAFFHP--PTHPQE----------------------------TGSPFPSPE 652 P GPSA P P HP + + SP +P Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 653 PPHS--------------LPTHYQPEPAKAFPFP--ADGLGAEGAFQCLEE---TPFPHE 693 P + LP P P A P P A + Q L TP Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368 Query: 694 GPEVGRGGLQGFP--RAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQ 751 P + +Q P + PP H SL+S SL L S + L Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPH-SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427 Query: 752 FCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811 + R SP P +PP +P + A +T L + Sbjct: 428 SFLTMSPRQTQASLTSPSRPA-STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486 Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871 L SLA+ P S L M SL +L P +++ Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL-------P 539 Query: 872 EPSGPRGPSSGHPLKSKAGVTPESKAP-----PPLPAATPDPQTP----RPGDRGCPARG 922 + P ++ PL + TP AP PP P TP P+TP P + PA Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599 Query: 923 RPKTRSLGLAP 933 P + L P Sbjct: 600 SPPLQGLPSPP 610 Score = 46.6 bits (109), Expect = 5e-04 Identities = 92/369 (24%), Positives = 124/369 (33%), Gaps = 59/369 (15%) Query: 3416 GRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAP---GPGEDRPPPRGSSPIL 3472 GR+P A R GA ++ G S P S P G GE PP + +SP Sbjct: 54 GRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP-- 111 Query: 3473 SEGSLPALLHLCSEVAPSTTKGWPETLERPV---DPVTHPIRGCELPSNHQECPPPSLSP 3529 S P + P KG + E V P R ++ P+ Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171 Query: 3530 FPAALADGRGDCALDGALERPENEASPGSP--GP--LLQQALPLGASLPRPGARGQDAEG 3585 A+A + L RP A P P GP + A + P P AR + + G Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231 Query: 3586 KRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSS---SHMVSEGGPRGTFHKGSA 3642 G + P +R L +SS S + G PR H S Sbjct: 232 --------GGLQRPASRS-----------LSSSATPLSSPARSGPSARGTPRAPAHP-SQ 271 Query: 3643 TKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGP 3702 KP G Q+ R TP + P A+G L+ LA + P+ KA+P P Sbjct: 272 PKPKGLQAL---RPPQVTPPRKDAAP-----ALGPLSSSPLATPS-----PSGTKARPVP 318 Query: 3703 SSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFP---SRSPAPERLPARAQAK 3759 + +P P T P S L + P PS P P+P P Sbjct: 319 PPDNAATPLPAT--------LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370 Query: 3760 SCTKGPREA 3768 S T P +A Sbjct: 371 SMTTPPMQA 379 Score = 42.7 bits (99), Expect = 0.007 Identities = 62/241 (25%), Positives = 88/241 (36%), Gaps = 46/241 (19%) Query: 3671 PRKAVGSLAPGELARGTENGMKPATPKAK---PGPSS---QGSGSPRPG----------- 3713 P ++ G+ + +R +G P AK PGP S + SG+ RPG Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138 Query: 3714 --TKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG-PREAGE 3770 T G + P L + + P+ + SPA R R++A G PR A Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR---RSRAAGTEVGLPRPAPS 195 Query: 3771 QGPHGSLGPKEKGESSTKRKKGQVPGPA--RSESVGSFGRAPSAPDKPPRTPRKQATPSR 3828 P K SS P PA R S G + P++ R+ ATP Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-----RSLSSSATPLS 250 Query: 3829 VLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEP 3888 P + P+++ PR P A P + P+G LRPP+ A P Sbjct: 251 S-PARSGPSARGTPRAP------AHPSQPK---------PKGLQALRPPQVTPPRKDAAP 294 Query: 3889 A 3889 A Sbjct: 295 A 295 Score = 42.0 bits (97), Expect = 0.012 Identities = 86/334 (25%), Positives = 103/334 (30%), Gaps = 62/334 (18%) Query: 3452 PGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIR 3511 P + P P PPP + P+ S PA + P P L P V P Sbjct: 718 PSATPPP--QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV--PPLLAAPPLQVP-PSP 772 Query: 3512 GCELPSNHQECPPPSLSP---------FPAALADGRGDCALDGA-------LERPENEAS 3555 LP + PPP P P+ A G + L P +A Sbjct: 773 PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832 Query: 3556 PGSPGPLLQ-----QALPLGASLPRPGARGQDAE--GKRAPLVFSGKRRAPGARGRCAPD 3608 P PLLQ A P + RP G D G R L + P +R Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------ 886 Query: 3609 HFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA----GCQSSSKDRSAASTPSKA 3664 S S +S GP H SAT G S + +AAS P A Sbjct: 887 --------------SPSSTLS--GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930 Query: 3665 LKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQG------SGSPRPGTKTGG 3718 HP AP RG P P PG S+ G + P T G Sbjct: 931 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG-SADGLCTIYETEGPESATPAPG 989 Query: 3719 GSQPQPASGQLQSETATTPAKPSFPSRSPAPERL 3752 P P+ G A A SRSP RL Sbjct: 990 ALDPGPSPG-TSGGKAAAGAGAGASSRSPKQARL 1022 Score = 41.2 bits (95), Expect = 0.020 Identities = 102/467 (21%), Positives = 143/467 (30%), Gaps = 63/467 (13%) Query: 3418 QPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSL 3477 +P + +R P + A P +A P + PPP ++ L +L Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP-ATL 331 Query: 3478 PALLHLCSEV--APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALA 3535 P L + + AP + P P P T P + + PPSL P Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP--- 388 Query: 3536 DGRGDCALDGALERPENEASPG---SPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVF 3592 ++ P + SP P PL +L SL P + + +P Sbjct: 389 -----------IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437 Query: 3593 SGKRRAPGARGRCAPDH--FQEDHLLQKEK--EVSSSHMVSEGGPRGTFHKGSATKPAGC 3648 +P PD Q L + S S VS T H A Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497 Query: 3649 QS----------------SSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMK 3692 S SS + TP +L P P + + SLAP L + Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP--PLENLPSLAPPPLQTASAPLTT 555 Query: 3693 P--ATP--------KAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETAT-TPAKPS 3741 P TP +A P P + +P P T + + P A L S P+ P Sbjct: 556 PHLETPPCPAPCPLQAPPSPLT----TPPPETPSSIATPPPQAPPALASPPLQGLPSPPL 611 Query: 3742 FPSRSPAPERLPARAQAK-SCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARS 3800 P +P P+ P A P + P + P+ + + P Sbjct: 612 SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671 Query: 3801 ESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPS 3847 F S P P TP QA PS P Q P PP S Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL-----QVPPSPPAS 713 Score = 40.8 bits (94), Expect = 0.027 Identities = 56/219 (25%), Positives = 74/219 (33%), Gaps = 23/219 (10%) Query: 3668 PVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASG 3727 PV P S AP LA P +P A P S + P+ + P A+ Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQ--VPPSPPASPPMSPSATPPPQ--------APPPLAAP 733 Query: 3728 QLQSETATTPAKPSFPSRSPAPERLPARAQAK-SCTKGPREAGEQGPHGSLGPKEKGESS 3786 LQ + + P PS +P P P A P + P P+ + Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793 Query: 3787 TKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPS------RVLPTKPKPNSQN 3840 T + PA F + S P P TP QA P +V P+ P + Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853 Query: 3841 KPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKR 3879 PR PP+ P + RL A G P PP R Sbjct: 854 APRRPPT----PGPDTSVSGPRLTLALAPGPP--PPPSR 886 Score = 32.3 bits (72), Expect = 9.5 Identities = 36/129 (27%), Positives = 43/129 (33%), Gaps = 28/129 (21%) Query: 3193 SSAVAHLLNSITEPAPKHHRG-------KRSAGKAAGSPGDPWGQEGEAKKDSPGERAKP 3245 SSA H S TEP+P R +R A ++ S P + P R P Sbjct: 210 SSASEH---STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA---RSGPSARGTP 263 Query: 3246 RARSTPS----------NPDGAATPDSASATALADAGS-----PGPPRTTPSPSPDPWAG 3290 RA + PS P P +A AL S P P T P P P Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNA 323 Query: 3291 GEPLLQATP 3299 PL P Sbjct: 324 ATPLPATLP 332 Score = 32.3 bits (72), Expect = 9.5 Identities = 30/104 (28%), Positives = 35/104 (33%), Gaps = 15/104 (14%) Query: 3204 TEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSN--------PD 3255 T AP H + G A P +A + P A +PS PD Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321 Query: 3256 GAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299 AATP A+ P PP TP P P P LQ P Sbjct: 322 NAATPLPATLP-------PSPPLATPLPLAPPSPSAPPSLQTLP 358 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 107 bits (267), Expect = 2e-22 Identities = 356/1416 (25%), Positives = 449/1416 (31%), Gaps = 237/1416 (16%) Query: 31 SQPPLEDNTP-----ATRTTKGAREAGGQAQAMELPEA----QPRQARDG-ELKPPSLRG 80 +QPP+ + P A T G ++ G + ++ E P+ A E P Sbjct: 167 AQPPVLGHGPRFISIAGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDN 226 Query: 81 QAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENP 140 AP++T +G P+TP R + R GR ++ I +S P ++ EN Sbjct: 227 LAPAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPP---DSAENQ 283 Query: 141 QLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQE---PPSSFTSTNYT 197 + +P+ +TP AP P P + G + E P S T T Sbjct: 284 --TSTDIPKTETP------APNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELG-T 334 Query: 198 SPSATPRPPAPGPPQSRG--------TSPLQPGSYPEYQASGADSWPPAAENSFPGANFG 249 + R G + G S Q +P GA P E G F Sbjct: 335 LETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEK---GQQFE 391 Query: 250 VPPAEP----------EPIPKGSRPGGSPRGVSFQFPFPALHGASTKP-----FPADVAG 294 PP P P P G P G + P + G P P AG Sbjct: 392 GPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAG 451 Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVG-TGPAYP--LPTQPAPSPLPCYQGQPG-----GLN 346 +F P+ F Q Q + + GP P L +P P LP + G G G Sbjct: 452 GSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQ 511 Query: 347 RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILP-ERPPSAQDGLGSTRGPPSSLPQRH 405 L G PG RP +D + LP + P G G P QR Sbjct: 512 GPRGLQGPHGPPGRVGKMGRPGADG-----ARGLPGDTGPKGDRGFDGLPGLPGEKGQRG 566 Query: 406 FPGQAYRASGVDTSPGPP--DTELAAPGPP----PARLP---QLWDPTAAPYPT-PPG-- 453 G PGPP D E A GPP A P L P +P PT PG Sbjct: 567 DFGHV-------GQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVT 619 Query: 454 ---GPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVL--PTARPSPHGMEMLSRLPFPA 508 G A ++ G+P P + S LP PQ L P G + LP Sbjct: 620 GIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSD 679 Query: 509 G--------GPEWQGGSQGALGTAGKT--PGPREKLPAVRSSQGGSPALFTYNGMTDPGA 558 G GP + G+QG G+AG PGPR V+ + G+ L G Sbjct: 680 GPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR----GVKGT-SGNRGLQGEKGEKGEDG 734 Query: 559 QPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPL--------PSPATNTAGSTCSSLSP 610 P F G + G P P PR G E P P + + Sbjct: 735 FPGFKGDVGLK-GDQGKPGAPGPR--GEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791 Query: 611 MSSSPANPSSEES-QLPGPLGPSAFFHPPTHPQETGSPFPSPE--PPHSLPTHYQPEPAK 667 + P P + S PGPLGP +TG P E PP S QP A Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGP---IGEKGKSGKTGQPGLEGERGPPGSRGERGQP-GAT 847 Query: 668 AFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQ 726 P P +G +GA P E G GLQG P P P P H Sbjct: 848 GQPGPKGDVGQDGA---------PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGR---- 894 Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGH---QRSPGPPGLPSPPAAPRVP 783 R G+L + K G GPPG P PP +P Sbjct: 895 -----PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLP 949 Query: 784 ADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP-FPLPASDLDMEDDAKLDS 842 GL G GK+ P P P P P ++ D Sbjct: 950 -----GLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTG---LKGDKGPPG 1001 Query: 843 LITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPL- 901 + + E P E P GP G + G T + P PL Sbjct: 1002 PVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLG 1061 Query: 902 -----PAATPDPQTPRPGDRGCPAR-------------GRPKTRSLGLAPTEADAPSQGR 943 AA P + GD G P G+P R G A + G Sbjct: 1062 PLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIR--GPAGHPGPPGADGA 1119 Query: 944 QQRRGKQLKLFRKDLDSG-----GAAEGSGSGGGGRASGLRPRRND--GLGERPPPRPRR 996 Q RRG LF + D G G G G G + D +G P PR Sbjct: 1120 QGRRGPP-GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRG 1178 Query: 997 PRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQ 1056 P Q P + ++ P +P P R DP A G I Sbjct: 1179 P--QGP-TGSEGTPGLPGGVGQPGAVGEKGER--GDAGDPGPPGAPG----------IPG 1223 Query: 1057 QKNRLREYDFASESEEDEQPPPRG-PGFRGRRGR-GEKRKEVELTQGPREDEPQKPRKAA 1114 K + E + S P +G PG G +G G +L GP D + Sbjct: 1224 PKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDL--GPPGDPGVSGIDGS 1281 Query: 1115 RQEAGGDGAPANPEEPGGS-RPGPGRSPQARGPS-------RSLETGAAAREG------- 1159 E G G P PG S PG P RGPS R E GA G Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341 Query: 1160 -GPKCADRP--SVAPKDPLQVPTNT-ETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215 GP A P V P+ +P E P P P D+ E Sbjct: 1342 TGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGE 1401 Query: 1216 -------ALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTP 1268 L PP AGE G GL + PP + D G P P GSL + P P Sbjct: 1402 KGHIGLIGLIGPPGE-AGEKG-DQGLPGVQGPPGPKGDPGPPGPIGSLGHPGP------P 1453 Query: 1269 GVGSLLGGPGGTQAPVSHNSKDP--PARQPGEFLAP 1302 GV LG G +P S + PA PG AP Sbjct: 1454 GVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489 Score = 75.9 bits (185), Expect = 8e-13 Identities = 226/908 (24%), Positives = 283/908 (31%), Gaps = 196/908 (21%) Query: 2 PGER----PRGAPPPT-------MTGDLQPRQVASSPGHPSQPPLEDNTPATRT------ 44 PG R PRG+P PT + G + PG P P + N + Sbjct: 598 PGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL 657 Query: 45 --TKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQ-------APSSTPGKRGSPQT 95 T G + G LP + G P +G P PG RG T Sbjct: 658 IGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGT 717 Query: 96 PPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTL-----DETPENPQLEAAQLPEV 150 R LQ G +G P + +G+ + KP ++ PE P+ +A Q E Sbjct: 718 SGNRG-LQGEKGEKGE-DGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEE 775 Query: 151 DTPQGPGTGAPLR-PGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSATPRPPA- 207 P G L PGLP +P + +GF P S P Sbjct: 776 GPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF-------PGPLGPIGEKGKSGKTGQPGL 828 Query: 208 ---PGPPQSRGT-----SPLQPGSYPEYQASGADSWPPAAENSFPGAN----FGVPPAEP 255 GPP SRG + QPG + GA P E PG F P P Sbjct: 829 EGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIP--GEKGLPGLQGPPGFPGPKGPP 886 Query: 256 EPIPKGSRPG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313 K RPG G + FQ G + P PA V G PQG Sbjct: 887 GHQGKDGRPGHPGQRGELGFQ-------GQTGPPGPAGVLG--------------PQGK- 924 Query: 314 PEEAVGTGPAYPLPTQPAPSPL--PCYQGQPGGLNRHSDLSGALSSPG--------AAHS 363 TG PL + P P P QG PG L G L PG Sbjct: 925 ------TGEVGPLGERGPPGPPGPPGEQGLPG-LEGREGAKGELGPPGPLGKEGPAGLRG 977 Query: 364 APRPFSDSLHKSLTKILPERPPSAQDGLGST---RGPPSSLPQRHFPGQAYRASGVDTSP 420 P P T + ++ P G + RGP PGQ SG + Sbjct: 978 FPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQ----SGSEGPV 1033 Query: 421 GPPDT-----ELAAPGPP-----PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPS- 469 GP E PGP P L L P AA GP G P Sbjct: 1034 GPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAA-------GPSGEEGDKGDVGAPGH 1086 Query: 470 PGQRLCLPQSAPLPWPQVL-PTARPSPHGMEMLSRLPFPAG--GPEWQGGSQGALGTAGK 526 G + + P P + P P P G + P G G + G +G +G G Sbjct: 1087 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGP 1146 Query: 527 T--------PGPREKLPAVRS-SQGGSPALFTYNGMTDPGAQP-LFFGVAQPQV------ 570 PG + ++ V S G+P G T P L GV QP Sbjct: 1147 PGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGE 1206 Query: 571 -------SPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623 P G P +P P+ +S PS A G P A S + Sbjct: 1207 RGDAGDPGPPGAPGIPGPKGDIGEKGDSG-PSGAAGPPGKK----GPPGEDGAKGSVGPT 1261 Query: 624 QLPGPLGP------SAFFHPPTH---PQETGSPFP--------SPEPPHSL-PTHYQ--- 662 LPG LGP S P P + G P P +P PP P+ + Sbjct: 1262 GLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGRE 1321 Query: 663 ----PEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPE--------VGRGGLQGFP-RAP 709 + AK P P G G P GPE VG GL G P + Sbjct: 1322 GREGEKGAKGEPGPDGPPGRTGPMGA--RGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMG 1379 Query: 710 PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG 769 PP P L D T + ++ + L + G + G Q PG Sbjct: 1380 PPGPLGPSGLPGLKGD------TGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPG 1433 Query: 770 PPGLPSPP 777 P G P PP Sbjct: 1434 PKGDPGPP 1441 Score = 58.2 bits (139), Expect = 2e-07 Identities = 241/1074 (22%), Positives = 329/1074 (30%), Gaps = 210/1074 (19%) Query: 466 GQPS---PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--GSQGA 520 G+P+ GQ+ P AP P V P+ P P G P PAG P G G +G Sbjct: 379 GEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGP 438 Query: 521 LGTAGKTP----GPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTP 576 GT P G K P V Q + A+ ++ G +P P G P Sbjct: 439 PGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRP--GPVGLP 496 Query: 577 SLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFH 636 P + G +E P + M A+ + GP G F Sbjct: 497 G--HPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDG 554 Query: 637 PPTHPQETGSP-----FPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691 P P E G P PP P P P G G L P Sbjct: 555 LPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGP----PGPTGQAGEPGPRGLLGPRGSP 610 Query: 692 HEGPEVGRGGLQGFPRA-----PPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAF 746 G G+ G P A PP P Sbjct: 611 GPTGRPGVTGIDGAPGAKGNVGPPGEP--------------------------------- 637 Query: 747 LAHRQFCGLLLARAKDGHQRSPGP------PGLPSPPAAPRVPA-DAHAGLLSHAKTFLL 799 G + G Q PGP PG PP P +P G L H Sbjct: 638 -------GPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGP 690 Query: 800 AGDAQAEGKDDPLRTGFLPSLAATP-FPLPASDLDMEDDAKLDSLITEALNGMEYQSDNP 858 G+ A+G P A P +P P + L + G + + P Sbjct: 691 TGEKGAQGP---------PGSAGPPGYPGPRGVKGTSGNRGL-----QGEKGEKGEDGFP 736 Query: 859 EIDSSFIDVFADE-EPS--GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGD 915 + + D+ +P GPRG K +AG E P +A + PG Sbjct: 737 GFKGD-VGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPG---SAGEKGKLGVPGL 792 Query: 916 RGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRA 975 G P R PK S+G +G+ + G+ Sbjct: 793 PGYPGRPGPKG-SIGFPGPLGPIGEKGKSGKTGQP------------------------- 826 Query: 976 SGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPR----VPRAAALPEETRSSRRRRLP 1031 GL GER PP R R Q PG+ P P+ A +P E + P Sbjct: 827 -GLE-------GERGPPGSRGERGQ-PGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP 877 Query: 1032 PRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGR-G 1090 P+ G G+ + E F ++ PP G G +G+ G Sbjct: 878 GFPGPKGPPGHQGKDGRP------GHPGQRGELGFQGQTG-----PPGPAGVLGPQGKTG 926 Query: 1091 EKRKEVELTQGPR-----EDEPQKPRKAARQEAGGDGAPANP---EEPGGSR--PGPGRS 1140 E E +GP E P R+ A G+ P P E P G R PGP Sbjct: 927 EVGPLGE--RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGG 984 Query: 1141 PQARGPSRSL----ETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQE 1196 P GP+ G G P +R + P + +P + + P+ Sbjct: 985 PGDPGPTGLKGDKGPPGPVGANGSP--GERGPLGPAGGIGLPGQSGSEGPVGPA------ 1036 Query: 1197 AKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSL 1256 K+ E P T + + P G +G PG P + D G P GS Sbjct: 1037 GKKGSRGERGPPGPTG-KDGIPGP----LGPLGP-PGAAGPSGEEGDKGDVGAPGHKGSK 1090 Query: 1257 ANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPA--RQPGE-----FLAPVANPSST 1309 + G PG+ G PG A + + PP Q G+ F+ + P Sbjct: 1091 GDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQ 1150 Query: 1310 ACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQ-PYSSPHSELFLGPKDLAGCFLE 1368 P P ++ G + P G P +GPQ P S + G G E Sbjct: 1151 GLPGPPGEKGEVGDVG------SMGPHGAP-GPRGPQGPTGSEGTPGLPGGVGQPGAVGE 1203 Query: 1369 ELHPKPSARDAPPASSSCLCQDGE--DAGSLEPQLPRSPPGTAETEPGRAASPPTLESSS 1426 + + PP + G+ + G P PPG + PG + ++ + Sbjct: 1204 KGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPG-KKGPPGEDGAKGSVGPTG 1262 Query: 1427 LFPDL--------------PVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPS 1466 L DL P ++ DP G SG P A PP K PS Sbjct: 1263 LPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA-PGPPGKRGPS 1315 Score = 55.1 bits (131), Expect = 1e-06 Identities = 94/359 (26%), Positives = 128/359 (35%), Gaps = 41/359 (11%) Query: 3543 LDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA-EGKRAPLVFSGKRRAPGA 3601 L G RP + S G PGPL P+G + G GQ EG+R P G+R PGA Sbjct: 792 LPGYPGRPGPKGSIGFPGPLG----PIGEK-GKSGKTGQPGLEGERGPPGSRGERGQPGA 846 Query: 3602 RGRCAP--DHFQEDHL-LQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAA 3658 G+ P D Q+ + EK + GP G G P + Sbjct: 847 TGQPGPKGDVGQDGAPGIPGEKGLPGLQ-----GPPG--FPGPKGPPGHQGKDGRPGHPG 899 Query: 3659 STPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGG 3718 + P G L P +G + P + PGP PG + Sbjct: 900 QRGELGFQGQTGPPGPAGVLGP----QGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955 Query: 3719 GSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREA-GEQGPHGSL 3777 G A G+L P+ P P+ P GP G++GP G + Sbjct: 956 G-----AKGELGPPGPLGKEGPAGLRGFPGPKGGPG-------DPGPTGLKGDKGPPGPV 1003 Query: 3778 G----PKEKGESSTKRKKGQVPGPARSES-VGSFGRAPSAPDK-PPRTPRKQATPSRVLP 3831 G P E+G G +PG + SE VG G+ S ++ PP K P + P Sbjct: 1004 GANGSPGERGPLGPAGGIG-LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGP 1062 Query: 3832 TKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAE 3890 P P + + PGH K G A P G+P +R P GA+ A+ Sbjct: 1063 LGP-PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQ 1120 Score = 54.7 bits (130), Expect = 2e-06 Identities = 133/534 (24%), Positives = 178/534 (33%), Gaps = 74/534 (13%) Query: 3413 LRGGRQPFAFRGVR-RPGA---PGQKARALEGTLPSKRRRVAMPG-----SAPGP----- 3458 L G R P RG R +PGA PG K + P +PG PGP Sbjct: 828 LEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPG 887 Query: 3459 --GED----RPPPRGSSPILSEGSLPALLHLCS------EVAPSTTKGWPETLERPVDPV 3506 G+D P RG + P + EV P +G P P + Sbjct: 888 HQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG 947 Query: 3507 THPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQA 3566 + G E P P PA L G G + G PGP+ Sbjct: 948 LPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANG 1007 Query: 3567 LP--LGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSS 3624 P G P G G P+ +GK+ + G RG P +D + + Sbjct: 1008 SPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTG--KDGIPGPLGPLGP 1065 Query: 3625 SHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSK-ALKFPV-HPRKAVGSLA--- 3679 G G KG P G + S D+ A P + ++ P HP A Sbjct: 1066 PGAAGPSGEEGD--KGDVGAP-GHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGR 1122 Query: 3680 ---PGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATT 3736 PG + ++G++ P P QG P PG K G G + A Sbjct: 1123 RGPPGLFGQKGDDGVRGFVGVIGP-PGLQGLPGP-PGEKGEVGDV-----GSMGPHGAPG 1175 Query: 3737 PAKPSFPSRSPAPERLPARAQAKSCT--KGPR-EAGEQGPHGSLG---PK----EKGESS 3786 P P P+ S LP KG R +AG+ GP G+ G PK EKG+S Sbjct: 1176 PRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG 1235 Query: 3787 TKRKKGQVPG----PARSESVGSFGRAPSAPDKPPR----------TPRKQATPSRVLPT 3832 G PG P + GS G D P +P ++ P V Sbjct: 1236 PSGAAGP-PGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGP 1294 Query: 3833 KPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGA 3886 P P + +P P ++ GH R+ R G+ +G P P T GA Sbjct: 1295 GP-PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGA 1347 Score = 52.0 bits (123), Expect = 1e-05 Identities = 125/475 (26%), Positives = 159/475 (33%), Gaps = 87/475 (18%) Query: 3428 PGAPGQKAR-ALEGTLPSKRRRVAMPGSAPG-------PGED--RPPPRGSSPILSEG-- 3475 PG PG K EG P R + P PG PG D R P + P G Sbjct: 496 PGHPGLKGEEGAEG--PQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFD 553 Query: 3476 SLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNH-----QECPPPSLSPF 3530 LP L +G + +P P RG E P + P L P Sbjct: 554 GLPGL------PGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPR 607 Query: 3531 PAALADGR-GDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAEGKRA 3588 + GR G +DGA N PG PGP QQ LP P G G G++ Sbjct: 608 GSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIG--TPGEKG 665 Query: 3589 PLVFSGKRRAPGARGRCA-PDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAG 3647 P G PG+ G P H + S+ GPRG KG++ G Sbjct: 666 PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGV--KGTSGN-RG 722 Query: 3648 CQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGS 3707 Q ++ P G++ + G KP PGP + Sbjct: 723 LQGEKGEKGEDGFPG----------------FKGDVGLKGDQG-KPGA----PGPRGE-D 760 Query: 3708 GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL--------PARAQAK 3759 G P + G + P + P P +P R P P+ P + K Sbjct: 761 GPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGR-PGPKGSIGFPGPLGPIGEKGK 819 Query: 3760 SCTKG-PREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPR 3818 S G P GE+GP GS +GE GQ PGP VG G AP P + Sbjct: 820 SGKTGQPGLEGERGPPGS-----RGERGQPGATGQ-PGP--KGDVGQDG-APGIPGE--- 867 Query: 3819 TPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRK-AEPGHTQRKDRLGKAFPQGRP 3872 + LP P P+ PP Q K PGH ++ LG G P Sbjct: 868 ---------KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPP 913 Score = 51.6 bits (122), Expect = 2e-05 Identities = 281/1166 (24%), Positives = 358/1166 (30%), Gaps = 216/1166 (18%) Query: 1633 PASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDV 1692 P SF A + Q L P P G PV G GL EG P Sbjct: 458 PVSFQQAQAQAV-LQQTQLSMKGPPGPVGLTGRPGPVGLPG--HPGLKGEEGAEGPQGPR 514 Query: 1693 CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCE--QRGGFLP 1750 L P PG G + + D P + D L LP E QRG F Sbjct: 515 GLQGPHGPPGR---VGKMGRPGADGARGLPGDT-GPKGDRGFDGLPGLPGEKGQRGDF-- 568 Query: 1751 EPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGR 1810 H G P P +G PP P G + +G R Sbjct: 569 -------GHVGQPGPPGEDGE----------RGAEGPP----GPTGQAGEPGPRGLLGPR 607 Query: 1811 AGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPAL 1870 G PT GRPG G + AP GA P G P P H S+ L Sbjct: 608 --GSPGPT-GRPGVTGIDGAP-GAKGNVGPPGE-------PGPPGQQGNHGSQ-----GL 651 Query: 1871 SPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGS 1930 P + PG GI GL P + P + G EG T E G + G Sbjct: 652 PGPQGLIGTPGEKGPPGNPGIPGL----PGSDGP--LGHPGHEGPTGEKGAQGPPGSAGP 705 Query: 1931 PGGVQVTTLPAVAGHQLGLEAD-------------GHWGLLGQAEKTQGQGTANQLQPEN 1977 PG + +G++ GL+ + G GL G K G + PE Sbjct: 706 PGYPGPRGVKGTSGNR-GLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764 Query: 1978 GVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRES 2037 P G A P +A G L G + P P P E Sbjct: 765 ---PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKG----SIGFPGPLGPIGEK 817 Query: 2038 LALALTAAHSRSGSEGRTPERAS--SPGLNKPLLATGDSPAPSVGDLAAC-APSPTSAAH 2094 T G G R PG ATG P P GD+ AP Sbjct: 818 GKSGKTGQPGLEGERGPPGSRGERGQPG------ATGQ-PGPK-GDVGQDGAPGIPGEKG 869 Query: 2095 MPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRD---------PPGPQQLLACSPAWA 2145 +P GP P P G G+ P P R PPGP +L Sbjct: 870 LPGLQGPPGFPGPKGPPGHQ--GKDGR-PGHPGQRGELGFQGQTGPPGPAGVLG------ 920 Query: 2146 PLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSV 2205 P + V + G P P + +E G L G PL P + Sbjct: 921 PQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGEL--GPPGPLGKEG---PAGL 975 Query: 2206 SAVTCTHSGDTPKDSTLRIPEDSRKEKLWESP-GRATSPPLAGAVSPSVAVRATGLSST- 2263 G P D P + +K P G SP G + P+ + G S + Sbjct: 976 RGFPGPKGG--PGDPG---PTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSE 1030 Query: 2264 ----PTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPS-------NTARLGH 2311 P G + G RG PGP + G P P P + PS + GH Sbjct: 1031 GPVGPAGKKGSRGERGPPGPTGKD-GIPGPLGPLGPP---GAAGPSGEEGDKGDVGAPGH 1086 Query: 2312 R--EGQAVTAVPTEPPTLQG-AGPDSPACLEGEMGTSSKEPEDPGT-PETGRSGATKMPR 2367 + +G A P P ++G AG P +G G PG + G G Sbjct: 1087 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP----PGLFGQKGDDGVRGFVG 1142 Query: 2368 VTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKP 2427 V P GL D S P H + PQG P G + G + Sbjct: 1143 VIGPPGLQGLPGPPGEKGEVGDVGSMGP--HGAPGPRGPQG-PTGSEGTPGLPGGVGQPG 1199 Query: 2428 ASTENGQWKGQAPHGPVTCEVCAA-------SFRSGP-GLSRHKARKHRP-HPGAPAEPS 2478 A E G+ GP SGP G + +K P GA Sbjct: 1200 AVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVG 1259 Query: 2479 PAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPG 2538 P LP PP VSG + +GDP V P P S E APG Sbjct: 1260 PTGLPGD---------LGPPGDPG--VSGIDGSPGEKGDPGDVGGPGPPGASGEP-GAPG 1307 Query: 2539 SPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRR-EPTVDSPS 2597 P + P+ H E REG + + EP D P Sbjct: 1308 PPGKR-----GPSGH-----------------------MGREGREGEKGAKGEPGPDGP- 1338 Query: 2598 HSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEG-- 2655 G++ + R+ E + + V G P PS ++G Sbjct: 1339 --PGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDT 1396 Query: 2656 GPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDR--MLCPGRMDGAALG 2713 GP+ + + +GP E + DQ G G Q PPG + PG + +LG Sbjct: 1397 GPKGEKGHIGLIGLIGP-PGEAGEKGDQ-----GLPGVQGPPGPKGDPGPPGPI--GSLG 1448 Query: 2714 EQ-------PTGQKGA-SARGFWGPR 2731 P GQKG+ + G GPR Sbjct: 1449 HPGPPGVAGPLGQKGSKGSPGSMGPR 1474 Score = 40.8 bits (94), Expect = 0.027 Identities = 106/459 (23%), Positives = 143/459 (31%), Gaps = 72/459 (15%) Query: 1683 EGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPC 1742 +GD+ PP + P+ PGP G+ + P Q+ +D +R Sbjct: 1093 KGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP----------PGLFGQKGDDGVRGFV- 1141 Query: 1743 EQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHA 1802 G + PG +G P P + GD + + P GA Sbjct: 1142 ----GVIGPPGL-----QGLPGPPG----------EKGEVGD----VGSMGPHGAPGPRG 1178 Query: 1803 AQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPS 1862 QG + L G+PG G E G + P G P ++ PS Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVG-EKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPS 1237 Query: 1863 RRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPP-RVNPSGLEGGTVEGGK 1921 + P P PG AK G GL P PP SG++G E G Sbjct: 1238 GAAGPPGKKGP------PGEDGAKGSVGPTGL----PGDLGPPGDPGVSGIDGSPGEKGD 1287 Query: 1922 VACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSP 1981 G PG P G + GH G G+ + +G P P Sbjct: 1288 PGDVGGPGPPGASGEPGAPGPPGKR---GPSGHMGREGREGEKGAKGEPGPDGPPGRTGP 1344 Query: 1982 -GGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSP-----PSPNR 2035 G V + GP LL G+ M P+ P P Sbjct: 1345 MGARGPPGRVGPEGLRGIPGPVGEPGLL----GAPGQMGPPGPLGPSGLPGLKGDTGPKG 1400 Query: 2036 ESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD-SPAPSVGDLAACAPSPTSAAH 2094 E + L G G ++ PG+ P GD P +G L P P A Sbjct: 1401 EKGHIGLIGLIGPPGEAGEKGDQ-GLPGVQGPPGPKGDPGPPGPIGSLG--HPGPPGVA- 1456 Query: 2095 MPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133 GPL ++ SP + G G PA P PPG Sbjct: 1457 -----GPLGQKGSKGSPG-SMGPRGDTGPAGPP--GPPG 1487 Score = 40.0 bits (92), Expect = 0.046 Identities = 35/118 (29%), Positives = 41/118 (34%), Gaps = 13/118 (11%) Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPG-----DPWGQEGEAKKDSPGE 3241 P G GS L + +P +G+R G PG P G GE P Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSG 1238 Query: 3242 RAKPRARSTPSNPDGAATPDSASATAL-ADAGSPGPPRT-----TPSPSPDPWAGGEP 3293 A P + P DGA S T L D G PG P +P DP G P Sbjct: 1239 AAGPPGKKGPPGEDGA--KGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGP 1294 Score = 39.3 bits (90), Expect = 0.078 Identities = 137/542 (25%), Positives = 175/542 (32%), Gaps = 134/542 (24%) Query: 3452 PGSAPGPGE--------DRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWP--ETLER 3501 PG GPG+ D+ PP P+ + GS + P+ G P E Sbjct: 979 PGPKGGPGDPGPTGLKGDKGPP---GPVGANGSPGER----GPLGPAGGIGLPGQSGSEG 1031 Query: 3502 PVDPV----THPIRGCELPSNHQECPPP--SLSPFPAALADGR-GDCALDGALERPENEA 3554 PV P + RG P+ P P L P AA G GD GA ++ Sbjct: 1032 PVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKG 1091 Query: 3555 SPGSPGPLLQQAL--PLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCA---PDH 3609 G GP Q + P G P PGA G A+G+R P G++ G RG P Sbjct: 1092 DKGDAGPPGQPGIRGPAGHPGP-PGADG--AQGRRGPPGLFGQKGDDGVRGFVGVIGPPG 1148 Query: 3610 FQEDHLLQKEK----EVSSSHMVSEGGPRG----TFHKGSATKPAGC-------QSSSKD 3654 Q EK +V S GPRG T +G+ P G + + Sbjct: 1149 LQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERG 1208 Query: 3655 RSAASTPSKALKFPVHPRKAVGSLA----------PGELARGTENGMKPAT-PKAKPG-- 3701 + P A P P+ +G PG+ E+G K + P PG Sbjct: 1209 DAGDPGPPGAPGIP-GPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDL 1267 Query: 3702 --PSSQG----SGSPRPGTKTG--GGSQPQPASGQLQSETATTPAKPSFPSR-------- 3745 P G GSP G GG P ASG+ P P P + Sbjct: 1268 GPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE--------PGAPGPPGKRGPSGHMG 1319 Query: 3746 ------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQ 3793 P P+ P R P G +G G GP GE GQ Sbjct: 1320 REGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGP--VGEPGLLGAPGQ 1377 Query: 3794 V--PGPARSES-------------------VGSFGRAPSAPDKPPR-TPRKQATPS-RVL 3830 + PGP +G G A +K + P Q P + Sbjct: 1378 MGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGD 1437 Query: 3831 PTKPKP-NSQNKPRPP----PSEQR--KAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAV 3883 P P P S P PP P Q+ K PG + G A P G PP + Sbjct: 1438 PGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPG-----PPGAPAEL 1492 Query: 3884 HG 3885 HG Sbjct: 1493 HG 1494 Score = 33.5 bits (75), Expect = 4.3 Identities = 64/280 (22%), Positives = 85/280 (30%), Gaps = 33/280 (11%) Query: 3635 GTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPA 3694 G KG+ +PA + + P P+ VG P G P Sbjct: 371 GAGEKGAKGEPAVIEKGQQFEGPPGAPG--------PQGVVGPSGPPG-PPGFPGDPGPP 421 Query: 3695 TPKAKPG-PSSQGSGSPRPGTK-------TGGGSQPQPASGQLQSETATTPAKPSFPSRS 3746 P PG P G P PGT GG + P S Q A Sbjct: 422 GPAGLPGIPGIDGIRGP-PGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGP 480 Query: 3747 PAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE-KGESSTKRKKGQVPGPARSESVGS 3805 P P L R P GE+G G GP+ +G + G++ P + G Sbjct: 481 PGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGL 540 Query: 3806 FGRAPSAPDKP----PRTPRKQATPSRV----LPTKPKPNSQNKPRPPPSEQRKA-EPGH 3856 G D+ P P ++ P P + + PP +A EPG Sbjct: 541 PGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGP 600 Query: 3857 TQRKDRLGKAFPQGRPLL-----RPPKRGTAVHGAEPAEP 3891 G P GRP + P +G EP P Sbjct: 601 RGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPP 640 Score = 33.5 bits (75), Expect = 4.3 Identities = 54/185 (29%), Positives = 70/185 (37%), Gaps = 42/185 (22%) Query: 2653 VEGGPEADGEQPPRLATLGPGVM--EGAAETDQEALCAGETGAQKPPGDRML--CPGRMD 2708 ++G P A G P PG G+ G G + PPG+ + PG D Sbjct: 621 IDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGS-D 679 Query: 2709 GAALG----EQPTGQKGASAR-------GFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757 G LG E PTG+KGA G+ GPR GV SG+ + + Sbjct: 680 GP-LGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR-----GVKGTSGNRGLQGE-----KG 728 Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSS 2817 E+G E+ P GF D QG P P +G GPEGP A + Sbjct: 729 EKG--EDGFP-----GFKGDVGLKGD-------QGKPGAPGPRGE-DGPEGPKGQAGQAG 773 Query: 2818 AKDPP 2822 + PP Sbjct: 774 EEGPP 778 Score = 32.3 bits (72), Expect = 9.5 Identities = 51/224 (22%), Positives = 71/224 (31%), Gaps = 41/224 (18%) Query: 2276 PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSP 2335 P +G P P R +G G ++ + + + PP PDS Sbjct: 229 PAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWT--SSPP------PDSA 280 Query: 2336 ACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSP 2395 E + T + E P T P V + GL T S D ++ Sbjct: 281 ---ENQTSTDIPKTETPAP----NLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELG 333 Query: 2396 QSHRNASHQTPQGDP--LGPQ----DLKQRS----------RGYKKKPASTENGQWKGQA 2439 A+ + +GD +GP + R+ +G K +PA E GQ Sbjct: 334 TLETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGP 393 Query: 2440 PHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP 2483 P P V S GP PG P P PA LP Sbjct: 394 PGAPGPQGVVGPSGPPGPP----------GFPGDPGPPGPAGLP 427 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 107 bits (266), Expect = 3e-22 Identities = 159/608 (26%), Positives = 213/608 (35%), Gaps = 80/608 (13%) Query: 144 AAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATP 203 AA+ P + TP+ PG+ P P P A LG P + + + Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPA-----ALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 204 RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSR 263 P GP +S GTS P S P ASG P A+N+ PG P + P +R Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPP--ASGRGERAPPAKNTSPG-----PVSSPGRASGTTR 125 Query: 264 PGG-SPRGVSFQFPFPALHGAST---KPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG 319 PG +G+ G +T K T+GP P A A G Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAG 184 Query: 320 TGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLS------GALSSPGAAHSAPRPFSDSLH 373 T P P P+ P P +G ++ S+ S A P A RP S SL Sbjct: 185 TEVGLPRPA-PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243 Query: 374 KSLTKIL-PERP-PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPG 431 S T + P R PSA+ G+ R P + QA R V PP + A Sbjct: 244 SSATPLSSPARSGPSAR---GTPRAPAHPSQPKPKGLQALRPPQVT----PPRKDAA--- 293 Query: 432 PPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTA 491 P L +++P TP P AA +S P+ L P LP A Sbjct: 294 ------PALGPLSSSPLATP--SPSAALQSQAPPTLPATPHSSSLTCQLATP----LPLA 341 Query: 492 RPSPHGMEMLSRLPFPAGGPEWQG----GSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547 PSP L LP P P Q GS T P P L + + +P Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP--PLSPLATPPPQAPPA 399 Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVG--------ASPSESPLPSPATN 599 + P + P A P +SP TPS P + + P P+ +P + Sbjct: 400 LALPPLQAPPSPP-----ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454 Query: 600 TAGSTCS-SLSPMSSSPANPSSEESQLPG------PLGPSAFFHPPTHPQETGSPFPSPE 652 A S S +P S +P + ++ Q+P P+ PSA P P P + Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514 Query: 653 PPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPF------PHEGPEVGRGGLQGFP 706 PP P P +A P P + F P P + P V L P Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574 Query: 707 RAPPPYPT 714 +PP PT Sbjct: 575 PSPPASPT 582 Score = 102 bits (253), Expect = 1e-20 Identities = 198/777 (25%), Positives = 256/777 (32%), Gaps = 170/777 (21%) Query: 10 PPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAME---------L 60 P G L PR PG P PP TPA GA A G+ E + Sbjct: 17 PAARAPGLLTPRP----PGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 61 PEAQPRQA--RDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQ 118 PE+ PR R + + P+S G+R P P+ +P R +G P Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130 Query: 119 RYILGIASSRT--KPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176 + L I++ T + E P+ L A + P PGT +P R A Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSRA----AGT 185 Query: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236 E+G R +PSA PRPP GP +S ++ + P Sbjct: 186 EVGLPR--------------PAPSARPRPPTEGPRKSVSSASEHSTTEPS---------- 221 Query: 237 PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHA 296 PAA P A G+ + + P SP A G S + P A + Sbjct: 222 PAARRR-PSAGGGLQRPASRSLSSSATPLSSP----------ARSGPSARGTPRAPAHPS 270 Query: 297 FTNGPLVFAFHQPQGAWPEEAVGTGPAY-PLPTQPAPSPLPCYQGQPGGLNRHSDLSGAL 355 + A PQ P + PA PL + P +P P S AL Sbjct: 271 QPKPKGLQALRPPQVTPPRK--DAAPALGPLSSSPLATPSP---------------SAAL 313 Query: 356 SSPGAAHSAPRPFSDSLHKSLTKILPERPPS--AQDGLGSTRGPPSSLPQRHFPGQAYRA 413 S P S SL L LP PPS A L + PP++ P QA + Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS-----QATTS 368 Query: 414 SGVDTS-------PGPPDTELAAPGP--PPA-RLPQLWDPTAAPYPTPPGGPLAATRSMF 463 G T P PP + LA P P PPA LP L P + P +PP PLA Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP-ASPPLSPLATPSPQA 427 Query: 464 FNG----------QPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPF--PAGGP 511 N P P + P S P P V P+A P L+ P P P Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPPSQAPPSLAAPPLQVPPSPP 486 Query: 512 EWQGGSQGALGTAGKTPGPREKLPAV-------RSSQGGSPALFT--YNGMTDPGA---- 558 S A TP P+ P + PAL T + P A Sbjct: 487 ASPPMSPSA------TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540 Query: 559 QPLFFGVAQPQVSPHGTPSLPPPRVVGA----------------SPSESPLPSPATNTAG 602 Q F A +SP TP P V+ A +P P P P T+ +G Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600 Query: 603 STCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQE--------TGSPFPSPEPP 654 + P S S L GP + P+E G SP P Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660 Query: 655 HSL--------------PTHYQPEPAKAFPF-PADGLGAEGAFQCLEETPFPHEGPE 696 L P ++ P P+ PA G G+ + ET EGPE Sbjct: 661 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET----EGPE 713 Score = 90.5 bits (223), Expect = 3e-17 Identities = 161/631 (25%), Positives = 210/631 (33%), Gaps = 141/631 (22%) Query: 8 GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATR-TTKGAREAGGQAQAMELPEAQPR 66 G P P M + R + G P P P T K A + P A+ R Sbjct: 170 GTPSPAMAR--RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227 Query: 67 QARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPS-----RLAGRAEGSPPQ--- 118 + G L+ P+ R + S+TP + P R +AP+ + G PPQ Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287 Query: 119 -----RYILGIAS--------------SRTKPTLDETPENPQLE---AAQLPEVDTPQGP 156 LG S S+ PTL TP + L A LP P P Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL--APPSP 345 Query: 157 GTGAPLR--PGLPRTEAQPAAEELG------FHRCFQEPP-SSFTSTNYTSPSATPRPPA 207 L+ P P T A LG H PP S + +P A PP Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405 Query: 208 PGPPQSRGTSPLQPGSYPEYQASGA---------DSWPPAAENSFPGANFGVPPAEPEPI 258 PP + PL P + P QA A S PP+ P + PPA P Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS----PPASPPVS 461 Query: 259 PKGSRPGGSPRGVS---FQFP--FPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313 P + P +P ++ Q P PA S P A PL A PQ Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA-- 519 Query: 314 PEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLH 373 A+ T P LP+ PA P GQ + S + S P + + P P + + Sbjct: 520 -PPALATPPLQALPSPPASFP-----GQ-------APFSPSASLPMSPLATPPPQAPPVL 566 Query: 374 KSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP 433 + +P PP A L + R PP+ P G + +PGPP PP Sbjct: 567 AAPLLQVPPSPP-ASPTLQAPRRPPTPGPDTSVSGPRLTLA---LAPGPP--------PP 614 Query: 434 PARLPQ--LWDPTAAPYPT------------------------PPGGPLAATRSMFFNGQ 467 P+R P L P A + + PP LAA ++ Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674 Query: 468 PSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKT 527 P+P APLPWP PA GP GS L T +T Sbjct: 675 PAPPLAFRGAPGAPLPWP---------------------PATGP----GSADGLCTIYET 709 Query: 528 PGPREKLPAVRSSQGGSPALFTYNGMTDPGA 558 GP PA + G P+ T G GA Sbjct: 710 EGPESATPAPGALDPG-PSPGTSGGKAAAGA 739 Score = 75.9 bits (185), Expect = 8e-13 Identities = 191/779 (24%), Positives = 256/779 (32%), Gaps = 214/779 (27%) Query: 1830 APAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKD 1889 A AGA++ T L P P + P PP+ L G A Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGS-------------PRPPPPVTPAALRVLGAA---- 50 Query: 1890 GILGLQELTPAA---------QSPPRVNPSGLEGGTVEGGKVACGPAQG----------- 1929 G +G + L A +S PR P+ GT + PA G Sbjct: 51 GAVGRKPLAERAGGIGGATIPESAPRAGPTR-SAGTSSRNPASRPPASGRGERAPPAKNT 109 Query: 1930 ------SPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPG- 1982 SPG TT P G + GL AE+T +G A + + +S G Sbjct: 110 SPGPVSSPGRASGTTRPGPLGQK---------GLRISAEETVARGKATEAPKRSALSAGA 160 Query: 1983 ---------GTDNHASVN----ASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPT-P 2028 GT + A A + L P A +G R ++S E T P Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220 Query: 2029 SPPS------------PNRESLALALT--AAHSRSGSEGR-TPERASSPGLNKP------ 2067 SP + P SL+ + T ++ +RSG R TP + P KP Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280 Query: 2068 ----LLATGDSPAPSVGDLAA---CAPSPTSA---------------AHMPCSLG-PLP- 2103 + AP++G L++ PSP++A + + C L PLP Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340 Query: 2104 --------------REDPLTSPSRAQGGLGGQL-----------PASPSCRDPPGPQQLL 2138 P T PS+A LG P SP PP L Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400 Query: 2139 ACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPS 2198 A P AP SP P T SP P ALA LLQ SP P Sbjct: 401 ALPPLQAP------------PSPPASPPLSPLATPSPQAP-NALAVHLLQAPFSPPPSPP 447 Query: 2199 SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVS------PS 2252 P S A TP + P L P SPP++ + + P Sbjct: 448 VQAPFSPPASPPVSPSATPPS---QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504 Query: 2253 VAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHR 2312 +A L+ P QA L P Q+ +PP + P G + +SPS + + Sbjct: 505 LAAPPLQLAKPP----PQAPPALATPPLQALPSPPASFP-----GQAPFSPSASLPM--- 552 Query: 2313 EGQAVTAVPTEPPTLQG----AGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRV 2368 T P PP L P PA + + P PG P+T SG PR+ Sbjct: 553 -SPLATPPPQAPPVLAAPLLQVPPSPPA---SPTLQAPRRPPTPG-PDTSVSG----PRL 603 Query: 2369 TCPSTGLGLGRTTAPS-STASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKP 2427 T L G PS S +S H +++ TP + RGY Sbjct: 604 T---LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP-----------EELRGY---- 645 Query: 2428 ASTENGQWKGQAPHGPVTCEVCA---ASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP 2483 ++G G A P E+ A A++ GP R PGAP PA P Sbjct: 646 ---DSGPEGGAAASPPPDAELAACHPAAWSRGPA----PPLAFRGAPGAPLPWPPATGP 697 Score = 75.5 bits (184), Expect = 1e-12 Identities = 192/818 (23%), Positives = 257/818 (31%), Gaps = 133/818 (16%) Query: 1639 GHAALLPCAQED--LVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQ------ 1690 G AA P A+ L P SPR PV A G A G + Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPP----PPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 Query: 1691 DVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLP 1750 +PE + + GP AG+ ++ + + + + A ++ + P G Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG--TT 124 Query: 1751 EPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAP-PLDATWPFGASPSHAAQGHSAG 1809 PG Q A E AP + GA P SP+ A + +AG Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184 Query: 1810 RAGGHLHPTAG---RPGFEGNEFAPAGAS--SLTAP----RGREAWLVPVPSPACVSNTH 1860 G P RP EG + + AS S T P R R + + PA S + Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244 Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920 + PA S P + P S+ GLQ L P +PPR + + Sbjct: 245 SATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP--------- 294 Query: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKT-----QGQGTANQLQP 1975 A GP SP T P+ A L QA T QL Sbjct: 295 --ALGPLSSSP---LATPSPSAA-------------LQSQAPPTLPATPHSSSLTCQLAT 336 Query: 1976 ENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNR 2035 ++P S+ P T P++ L + +LQ PSPP Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL-------GSPTLQATHSFLPSPPL--- 386 Query: 2036 ESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHM 2095 S TP + P L P L SP S PSP + + Sbjct: 387 ---------------SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 431 Query: 2096 PCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQA 2155 L P P + P +A P SPS P LA P P + Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASP 489 Query: 2156 TTDTGAEDSPVAPPSLTTSPC-------DPKEALAGCLLQGEGSPLEDPSSWPPGSVSAV 2208 A P APP L P ALA LQ SP P+S+P Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP---PASFP------- 539 Query: 2209 TCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP--SVAVRATGLSSTPTG 2266 G P + +P ++P +P L SP S ++A TP Sbjct: 540 -----GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 594 Query: 2267 DEAQAGRGL-----PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARL-GHREGQAVTAV 2320 D + +G L PGP P +P T GHSS + S L G+ G A Sbjct: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 654 Query: 2321 PTEPPTLQGA---------GPDSPACLEGEMGTSSKEP--EDPGTPE--------TGRSG 2361 + PP + A GP P G G P PG+ + G Sbjct: 655 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 714 Query: 2362 ATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHR 2399 AT P P G A + + S SP+ R Sbjct: 715 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 752 Score = 70.1 bits (170), Expect = 4e-11 Identities = 192/802 (23%), Positives = 262/802 (32%), Gaps = 125/802 (15%) Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR---GPSRSL-ETGAAAREGGPKCA 1164 K AAR A P PG RP P +P A G + ++ A R GG A Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 Query: 1165 DRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAAC 1224 P AP+ PT + + P+ P + E AP + + S P Sbjct: 69 TIPESAPRAG---PTRSAGTSSRNPASRPPASGRG-----ERAPPAKNTSPGPVSSPGRA 120 Query: 1225 AGEMGASP----GLLIPEQPPPSRHD-TGTPKPSGSLANTAPHGSSPTPGVGS------- 1272 +G P GL I + +R T PK S A S PTPG S Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180 Query: 1273 -LLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCD-PAG 1330 G G P PP P + ++ + S+T P P+ + G PA Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE-PSPAARRRPSAGGGLQRPAS 239 Query: 1331 FNRDPLGVPV---AKKGPQPYSSPHSELFLGPKDLAGCFLEELHPK---PSARDAPPASS 1384 + P+ A+ GP +P + G L+ L P P +DA PA Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQALRPPQVTPPRKDAAPALG 297 Query: 1385 SCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSL 1444 S P SP +++ +PPTL ++ P SL Sbjct: 298 PL---------SSSPLATPSPSAALQSQ-----APPTLPAT-------------PHSSSL 330 Query: 1445 SANRDSGLPFA----CADPPQKTVPSDPPYP--------SFLLLEEVSPMLPSHFPDLSG 1492 + + LP A A P +T+PS P P L+ LPS P LS Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS--PPLSP 388 Query: 1493 GKVLSKTCPPERTVVP-GAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSK 1551 PP + P A PS P +A S + + L + LQ Sbjct: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH--------LLQAPF 440 Query: 1552 DTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREG 1611 +P A + PPSQ A P + S + S Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500 Query: 1612 AESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQK 1671 A +A +P P + P A LP APFSP A+ P+ Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATPPLQA--LPSPPASFPGQAPFSP-SASLPMSPLAT 557 Query: 1672 AGASKTGLCQA---EGDSRPPQDVCLPEPSKQPGPQLDAG------SLAKC--------- 1713 + A + PP L P + P P D +LA Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617 Query: 1714 SPDQELSFPK-NKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPA 1772 SP LS P ++S+ + + LR GG P + PA + G Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP-- 675 Query: 1773 VHLAPDLAFQGDGAPPLDATWPFGASPSHA--------AQG-HSAGRAGGHLH--PTAGR 1821 AP LAF+ GAP WP P A +G SA A G L P+ G Sbjct: 676 ---APPLAFR--GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT 730 Query: 1822 PGFEGNEFAPAGASSLTAPRGR 1843 G + A AGASS + + R Sbjct: 731 SGGKAAAGAGAGASSRSPKQAR 752 Score = 68.6 bits (166), Expect = 1e-10 Identities = 204/849 (24%), Positives = 255/849 (30%), Gaps = 184/849 (21%) Query: 379 ILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLP 438 +L RPP GS R PP P A R G + G A G A +P Sbjct: 24 LLTPRPP------GSPRPPPPVTPA------ALRVLGAAGAVGRKPLAERAGGIGGATIP 71 Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP-----TARP 493 + +AP P ++R+ S P P P P T RP Sbjct: 72 E-----SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126 Query: 494 SPHGMEML--SRLPFPAGGPEWQGGSQGALG------TAGKTPGPREKLPAVRSSQGGSP 545 P G + L S A G + + AL T+G TPG A RS G+ Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186 Query: 546 ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPR--VVGASPSESPLPSPATNTAGS 603 G+ +P S P PR V AS + PSPA S Sbjct: 187 V-----------------GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229 Query: 604 TCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHP--PTHPQETGSPFPSPEPPHSLPTHY 661 L +S + S+ P GPSA P P HP + P P+ +L Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-----PKPKGLQAL---- 280 Query: 662 QPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSS 721 P + P D A G L +P P LQ +APP P S S Sbjct: 281 --RPPQVTPPRKDAAPALGP---LSSSPLATPSPSAA---LQS--QAPPTLPATPHSSS- 329 Query: 722 ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPR 781 LTC+ L A P LPSPPA P Sbjct: 330 ---------LTCQLATP------------------LPLAPPSPSAPPSLQTLPSPPATPP 362 Query: 782 VPADAHAG--LLSHAKTFLLAGDAQAEGKDDPLRTGFL--PSLAATPFPL---PASDLDM 834 A G L +FL + P L P L A P P P S L Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 422 Query: 835 EDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAG---- 890 ++L L +P + + F S P PS+ P ++ Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAAP 477 Query: 891 ---VTPESKAPPPL-PAATPDPQTP-----------RPGDRGCPARGRPKTRSLGLAPTE 935 V P A PP+ P+ATP PQ P +P + PA P ++L P Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP-- 535 Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPR 995 A P Q +A S P L + PP P Sbjct: 536 ASFPGQA----------------PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579 Query: 996 RPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELI---L 1052 P QAP R P P + + P T + P P R G +L Sbjct: 580 SPTLQAP--RRPPTPGPDTSVSGPRLTLA----LAPGPPPPPSRSPSSTLSGPDLAGHSS 633 Query: 1053 KIVQQKNRLREYDFASESEEDEQPPP-------------RGP----GFRGRRGRGEKRKE 1095 LR YD E PPP RGP FRG G Sbjct: 634 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG------- 686 Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155 L P E +G + PG PGP SP G + GA Sbjct: 687 APLPWPPATGPGSADGLCTIYET--EGPESATPAPGALDPGP--SPGTSGGKAAAGAGAG 742 Query: 1156 AREGGPKCA 1164 A PK A Sbjct: 743 ASSRSPKQA 751 Score = 67.0 bits (162), Expect = 3e-10 Identities = 104/390 (26%), Positives = 130/390 (33%), Gaps = 69/390 (17%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-NTPATRTTKGAREAGGQAQAMEL 60 P P PPP L + + P P+ PPL TP+ + A A+ L Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP--------NALAVHL 435 Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120 +A PPS QAP S P P +P P QAP LA PP Sbjct: 436 LQAP-------FSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPP--- 483 Query: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF 180 P +P + + P P P PL+ P +A PA Sbjct: 484 --------------SPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPL 528 Query: 181 HRCFQEPPSSFTSTNYTSPSAT------PRPPAPGPPQSRG---TSPLQPGSYPEYQASG 231 + PP+SF SPSA+ PP PP P P + P QA Sbjct: 529 -QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587 Query: 232 ADSWP-PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPA 290 P P S P + P P P P SP + P A H +S P Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPPPP------PSRSPSS-TLSGPDLAGHSSSATSTPE 640 Query: 291 DVAGHAFTNGPLVFAFHQPQ-----GAWPEEAVGTGPAYPL-----PTQPAPSPLPCYQG 340 ++ G + +GP A P A A GPA PL P P P P G Sbjct: 641 ELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698 Query: 341 QPGGLNRHSDLSG---ALSSPGAAHSAPRP 367 GL + G A +PGA P P Sbjct: 699 SADGLCTIYETEGPESATPAPGALDPGPSP 728 Score = 63.9 bits (154), Expect = 3e-09 Identities = 129/507 (25%), Positives = 168/507 (33%), Gaps = 57/507 (11%) Query: 2109 TSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWA----PL-EEADGVQATTDTGAED 2163 T +RA G L + P SP P P L A A PL E A G+ T E Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP--ES 73 Query: 2164 SPVAPP--SLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDST 2221 +P A P S TS +P P ++ S P S + T Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133 Query: 2222 LRIP--EDSRKEKLWESPGRA---------TSPPLAGAVSPSVAVRATGLSSTPTGDEAQ 2270 LRI E + K E+P R+ TS P G SP++A R S G E Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR-----SRAAGTEV- 187 Query: 2271 AGRGLPGPDPQSRGAPPHTNPDRMPRG---HSSYSPSNTARLGHREGQAVTAVPTEPPTL 2327 GLP P P +R PP P + HS+ PS AR G + + + Sbjct: 188 ---GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244 Query: 2328 QGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVT------CPSTGLGLGRTT 2381 SPA + + P P P+ A + P+VT P+ G Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304 Query: 2382 APSSTASDFQSDSPQSHRNASHQTPQGDPLG-PQDLKQRSRGYKKKPASTENGQWKGQAP 2440 A S ++ QS +P + H + L P L S P S + P Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS---PSAPPSLQT------LP 355 Query: 2441 HGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRK 2500 P T A + P L + P A P P A PA L PL PP Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA-LALPPLQAPPSPPAS 414 Query: 2501 KSHRVSGKERPNHSRGDPSHVTQ----PPPAQGSKEVLRAPGSPH-SQQLHPPS---PTE 2552 P H+ Q PPP+ + P SP S PPS P+ Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474 Query: 2553 HEVDVKTPASKPRPDQAREDELHPKQA 2579 ++ P S P P QA Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQA 501 Score = 62.4 bits (150), Expect = 9e-09 Identities = 121/496 (24%), Positives = 162/496 (32%), Gaps = 57/496 (11%) Query: 3416 GRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAP---GPGEDRPPPRGSSPIL 3472 GR+P A R GA ++ G S P S P G GE PP + +SP Sbjct: 54 GRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP-- 111 Query: 3473 SEGSLPALLHLCSEVAPSTTKGWPETLERPV---DPVTHPIRGCELPSNHQECPPPSLSP 3529 S P + P KG + E V P R ++ P+ Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171 Query: 3530 FPAALADGRGDCALDGALERPENEASPGSP--GP--LLQQALPLGASLPRPGARGQDAEG 3585 A+A + L RP A P P GP + A + P P AR + + G Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231 Query: 3586 KRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSS---SHMVSEGGPRGTFHKGSA 3642 G + P +R L +SS S + G PR H S Sbjct: 232 --------GGLQRPASRS-----------LSSSATPLSSPARSGPSARGTPRAPAHP-SQ 271 Query: 3643 TKPAGCQS--------SSKDRSAASTP--SKALKFPVHPRKAVGSLAPGELARGTENG-- 3690 KP G Q+ KD + A P S L P P A+ S AP L + Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP-SPSAALQSQAPPTLPATPHSSSL 330 Query: 3691 ---MKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQ--LQSETATTPAKPSFPSR 3745 + P A P PS+ S P SQ + G LQ+ + P+ P P Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390 Query: 3746 SPAPERLPARA-QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVG 3804 +P P+ PA A P + P + P+ + + P Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450 Query: 3805 SFGRAPSAPDKPPRTPRKQATPSRVLP---TKPKPNSQNKPRPPPSEQRKAEPGHTQRKD 3861 F S P P TP QA PS P P P + P + +A P Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510 Query: 3862 RLGKAFPQGRPLLRPP 3877 +L K PQ P L P Sbjct: 511 QLAKPPPQAPPALATP 526 Score = 59.3 bits (142), Expect = 7e-08 Identities = 94/399 (23%), Positives = 140/399 (35%), Gaps = 58/399 (14%) Query: 3523 PPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALP-------LGASLPR 3575 PPP ++P + G +P E + G G + ++ P G S Sbjct: 35 PPPPVTPAALRVLGAAGAVG-----RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89 Query: 3576 PGARGQ-DAEGKRAPLVFSGKRRAPG---ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEG 3631 P +R G+RAP K +PG + GR A + L QK +S+ V+ Sbjct: 90 PASRPPASGRGERAP---PAKNTSPGPVSSPGR-ASGTTRPGPLGQKGLRISAEETVA-- 143 Query: 3632 GPRGTFHKGSATK-PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENG 3690 +G AT+ P S+ R S P+ P R++ A GTE G Sbjct: 144 -------RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS--------RAAGTEVG 188 Query: 3691 MKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA--TTPAKPSFPSRSPA 3748 + P A+P P ++G ++P PA+ + S PA S S S Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL-SSSAT 247 Query: 3749 PERLPARA--QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVG-- 3804 P PAR+ A+ + P + P G + + ++ GP S + Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307 Query: 3805 --SFGRAPSAPDKPPRTPRKQ------ATPSRVLPTKPK--PNSQNKPRP---PPSEQRK 3851 S AP P TP ATP + P P P+ Q P P PPS+ Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367 Query: 3852 AEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAE 3890 + T + P PL PP + P + Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406 Score = 56.2 bits (134), Expect = 6e-07 Identities = 211/908 (23%), Positives = 270/908 (29%), Gaps = 179/908 (19%) Query: 1172 KDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL----RSPPAACAGE 1227 +D + T P L P+ P P + A R P A AG Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64 Query: 1228 MGASPGLLIPEQPP----------PSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGP 1277 +G G IPE P SR+ P SG AP + +PG S G Sbjct: 65 IG---GATIPESAPRAGPTRSAGTSSRNPASRPPASGR-GERAPPAKNTSPGPVSSPGRA 120 Query: 1278 GGTQAPVSHNSKDPPARQPGEFLAP---VANPSSTACPKPSVLSSKISSFGCDPAGFNRD 1334 GT P P Q G ++ VA +T PK S LS AG RD Sbjct: 121 SGTTRP-------GPLGQKGLRISAEETVARGKATEAPKRSALS----------AGARRD 163 Query: 1335 PLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDA 1394 G P P + S AG + P PSAR PP Sbjct: 164 TSGPTPGT--PSPAMARRSRA-------AGTEVGLPRPAPSARPRPPTEG---------- 204 Query: 1395 GSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF 1454 PR +A SP S L P SLS++ Sbjct: 205 -------PRKSVSSASEHSTTEPSPAARRRPSAGGGL-----QRPASRSLSSSATPLSSP 252 Query: 1455 ACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAP-- 1512 A + P + P P +PS + + + P + PP + P P Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPP------------QVTPPRKDAAPALGPLS 300 Query: 1513 SLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELG 1572 S P S AL S + L + L QL P LA L Sbjct: 301 SSPLATPSPSAALQSQ-APPTLPATPHSSSLTCQL-------ATPLPLAPPSPSAPPSLQ 352 Query: 1573 TGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPC 1632 T PP AT P + T S T + S +AT P P Sbjct: 353 TLPSPP-------ATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT-------PPPQAPP 398 Query: 1633 PASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDV 1692 + P A P A L A SP+ N A L QA PP Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPN----------ALAVHLLQAPFS--PP--- 443 Query: 1693 CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEP 1752 P P + A SP P + A ++ SL P + +P Sbjct: 444 --------PSPPVQAPFSPPASP------PVSPSATPPSQAPPSLAAPPLQ-----VPPS 484 Query: 1753 GTADQPHRGAPAPEAFGSPAVHLAP-DLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRA 1811 A P + P P + P LA APP AT P A PS A G+A Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS--FPGQA 542 Query: 1812 GGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALS 1871 P+A P +P AP A L+ VP S P L Sbjct: 543 P--FSPSASLP------MSPLATPPPQAPPVLAAPLLQVPPSPPAS----------PTLQ 584 Query: 1872 PPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSP 1931 P R P PG S G L P PP +PS GP Sbjct: 585 APRRP---PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS----------TLSGPDLAGH 631 Query: 1932 GGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVN 1991 +T + G+ G E G + G +P A Sbjct: 632 SSSATSTPEELRGYDSGPEG----GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 687 Query: 1992 ASPKTALTGP--TEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRS 2049 P TGP +G + + +G +A +P PSP + ++ A A A SRS Sbjct: 688 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 747 Query: 2050 GSEGRTPE 2057 + R E Sbjct: 748 PKQARLGE 755 Score = 56.2 bits (134), Expect = 6e-07 Identities = 128/549 (23%), Positives = 174/549 (31%), Gaps = 67/549 (12%) Query: 876 PRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQT----PRPGDRGC---------PARG 922 PR P+ G P KS + + S P PAA P RP R PAR Sbjct: 198 PRPPTEG-PRKSVSSASEHSTTEPS-PAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255 Query: 923 RPKTRSLGLAPTEADAPS-QGRQQRRGKQLKLFRKDLDSG-GAAEGSGSGGGGRASGLRP 980 P R AP P +G Q R Q+ RKD G S ++ L+ Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ- 314 Query: 981 RRNDGLGERPPPRPRRPRTQAPGSR-ADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKR 1039 + PP P P + + + A P P P + + P ++ PP P + Sbjct: 315 ------SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS---PPATPPSQA 365 Query: 1040 KARGGAWGKELI--------LKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGE 1091 G+ + L + A + PP P Sbjct: 366 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 425 Query: 1092 KRKE---VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSR 1148 + V L Q P P P +A + P + P P PS Sbjct: 426 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485 Query: 1149 SLETGAAAREGGPKCADRPSVAP-----KDPLQVPTNTET---SEETRPSLDFPQEAKEP 1200 + P A P AP K P Q P T P FP +A P Sbjct: 486 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA--P 543 Query: 1201 ETAEESAPDSTEFTEALRSPPAACAGEMG------ASPGLLIPEQPPPSRHDTGTPKPSG 1254 + S P S T ++PP A + ASP L P +PP DT P Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603 Query: 1255 SLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKP 1314 +LA P+ S L GP A S ++ P G P +++ P Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 661 Query: 1315 SVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAG-CFLEELHPK 1373 + + C PA ++R P P+A +G P GP G C + E Sbjct: 662 ELAA-------CHPAAWSRGP-APPLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGP 712 Query: 1374 PSARDAPPA 1382 SA AP A Sbjct: 713 ESATPAPGA 721 Score = 52.0 bits (123), Expect = 1e-05 Identities = 147/600 (24%), Positives = 180/600 (30%), Gaps = 96/600 (16%) Query: 3193 SSAVAHLLNSITEPAPKHHRG-------KRSAGKAAGSPGDPWGQEGEAKKDSPGERAKP 3245 SSA H S TEP+P R +R A ++ S P + P R P Sbjct: 210 SSASEH---STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA---RSGPSARGTP 263 Query: 3246 RARSTPSNPDG----AATPDSASATALADAGSPGP----PRTTPSPSPDPWAGGEPLLQA 3297 RA + PS P A P + A + GP P TPSPS + P L A Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323 Query: 3298 TPVHEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLG 3357 TP + C P P A S Q + P P L Sbjct: 324 TPHSSSLT--------CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 375 Query: 3358 GAHGLLERPELQHT----PLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHL 3413 H L P L P L ++ A + Q + HL Sbjct: 376 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 435 Query: 3414 RGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAP----GPGEDRPPPRGSS 3469 + PF+ P +P +A P P AP P PP +S Sbjct: 436 L--QAPFS-----PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488 Query: 3470 PILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSP 3529 P +S + P AP P L +P P P P PP S Sbjct: 489 PPMSPSATPP------PQAPPPLAAPPLQLAKP--PPQAPPALATPPLQALPSPPAS--- 537 Query: 3530 FPAALADGRGDCALDGALERPENEASPGSPGPLLQ-----QALPLGASLPRPGARGQDAE 3584 FP L P +A P PLLQ A P + RP G D Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597 Query: 3585 --GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSA 3642 G R L + P +R S S +S GP H SA Sbjct: 598 VSGPRLTLALAPGPPPPPSR--------------------SPSSTLS--GPDLAGHSSSA 635 Query: 3643 TKPA----GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKA 3698 T G S + +AAS P A HP AP RG P P Sbjct: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 695 Query: 3699 KPGPSSQG------SGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL 3752 PG S+ G + P T G P P+ G A A SRSP RL Sbjct: 696 GPG-SADGLCTIYETEGPESATPAPGALDPGPSPG-TSGGKAAAGAGAGASSRSPKQARL 753 Score = 49.7 bits (117), Expect = 6e-05 Identities = 184/789 (23%), Positives = 251/789 (31%), Gaps = 138/789 (17%) Query: 2014 SRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD 2073 +RA L +P PP P + L AA G+ GR P + G+ AT Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAA----GAVGRKPLAERAGGIGG---ATIP 71 Query: 2074 SPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133 AP G + S + A P + G R P + S G+ AS + R P Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR--ASGTTRPGPL 129 Query: 2134 PQQLLACSP----AWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQG 2189 Q+ L S A EA A + GA P T SP + + A G Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188 Query: 2190 EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV 2249 P PP + P+ S E S E SP A P AG Sbjct: 189 LPRPAPSARPRPPT-----------EGPRKSVSSASEHSTTEP---SPA-ARRRPSAGGG 233 Query: 2250 SPSVAVRATGLSSTPTGDEAQAG---RGLPG-------PDPQSRGA--PPHTNPDRM--- 2294 A R+ S+TP A++G RG P P P+ A PP P R Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293 Query: 2295 ----PRGHSSYS-PSNTARLGHREGQAVTAVP---------TEPPTLQGAGPDSPACLEG 2340 P S + PS +A L + + A P P L P +P L+ Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ- 352 Query: 2341 EMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRN 2400 P P TP + + + P + + L PS S + PQ+ Sbjct: 353 ------TLPSPPATPPSQATTSLGSPTLQATHSFL-------PSPPLSPLATPPPQAPPA 399 Query: 2401 ASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFR--SGPG 2458 + Q P P A QAP P A F + P Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459 Query: 2459 LSRHKARKHRPHPGAPAEP-------------SPAALPAQQPLEPLA----QKCQPPRKK 2501 +S + P A P SP+A P Q PLA Q +PP + Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519 Query: 2502 SHRVS---------------GKERPNHSRGDPSHVTQPPPAQG----SKEVLRAPGSPHS 2542 ++ G+ + S P PP Q + +L+ P SP + Sbjct: 520 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579 Query: 2543 QQL-----HPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPS 2597 PP+P T S PR A P R P D Sbjct: 580 SPTLQAPRRPPTP-----GPDTSVSGPRLTLALAP--GPPPPPSRSPSSTLSGP--DLAG 630 Query: 2598 HSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGP 2657 HS ++ +LRG E S ++ P A+++ P+ L+ G P Sbjct: 631 HSSSATSTPE-ELRGYDSGPEGGAAASPPPDAELAACHP----AAWSRGPAPPLAFRGAP 685 Query: 2658 EADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPT 2717 A PP GPG +G + G A PG L PG G + G+ Sbjct: 686 GAPLPWPP---ATGPGSADGLCTIYE---TEGPESATPAPG--ALDPGPSPGTSGGKAAA 737 Query: 2718 GQ-KGASAR 2725 G GAS+R Sbjct: 738 GAGAGASSR 746 Score = 42.7 bits (99), Expect = 0.007 Identities = 122/524 (23%), Positives = 167/524 (31%), Gaps = 96/524 (18%) Query: 3424 GVRRPGAPGQKARAL--EGTLPSKRRRVAMPGSAPGPGEDR----PPPRGSSPILSEGSL 3477 G RPG GQK + E T+ + A SA G R P P SP ++ S Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181 Query: 3478 PALLHLCSEVAPSTTKGWPETLE--RPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALA 3535 A T G P RP P P + S H + P PAA Sbjct: 182 AA----------GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TTEPSPAA-- 224 Query: 3536 DGRGDCALDGALERPENEASPGSPGPLLQQAL--PLGASLPRPGARGQDAEGK-----RA 3588 R + G L+RP + + S PL A P PR A + K R Sbjct: 225 --RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282 Query: 3589 PLVFSGKRRAPGARG------------------RCAPDHFQEDHLLQKEKEVSSSHMVSE 3630 P V ++ A A G + P H ++++ ++ Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342 Query: 3631 GGPRG-----TFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELAR 3685 P T AT P+ +S + +T S P+ P AP LA Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402 Query: 3686 G------TENGMKPATPKAKPGPSS---------QGSGSPRPGTKTGGGSQPQPASGQLQ 3730 + P +P A P P + Q SP P P PAS + Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPV- 460 Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGP---------KE 3781 S +AT P++ PS + P ++P A Q P P + Sbjct: 461 SPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519 Query: 3782 KGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPS------RVLPTKPK 3835 +T + PA F + S P P TP QA P +V P+ P Sbjct: 520 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579 Query: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKR 3879 + PR PP+ P + RL A G P PP R Sbjct: 580 SPTLQAPRRPPT----PGPDTSVSGPRLTLALAPGPP--PPPSR 617 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 105 bits (263), Expect = 7e-22 Identities = 310/1288 (24%), Positives = 388/1288 (30%), Gaps = 264/1288 (20%) Query: 3 GERPRG-----APP--PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQA 55 G+ P+G PP P GD SPG P P + ++ P G + Q Sbjct: 101 GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPT-----GPQNYSPQY 155 Query: 56 QAMELPEAQPRQARDGELKPPSLRGQ-APSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEG 114 + ++ G P G P T G GSP +P + P P + Sbjct: 156 DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPP 215 Query: 115 SPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLR-PGLPRTEAQP 173 PP +G + K P P E P PG P PG P + Sbjct: 216 GPPG--AIGPSGPAGKDGESGRPGRP-------GERGLPGPPGIKGPAGIPGFPGMKGHR 266 Query: 174 AAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAP-GPPQSRGTS--PLQPGSYPEYQAS 230 + + P + P P P G P RG P G+ A Sbjct: 267 GFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGAR 326 Query: 231 GADSWP----PAAENSFPGA--------------NFGVPPAEPEPIPKG-----SRPG-- 265 G+D P P FPG+ + G P EP P+G PG Sbjct: 327 GSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPP 386 Query: 266 ---GSPRGVSFQFP-----FPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEA 317 GSP G P P L GA P PA G G P Sbjct: 387 GINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR 446 Query: 318 VGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKS 375 G A +P P G PG G N +G +PG A Sbjct: 447 GERGEA-GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPA----------G 495 Query: 376 LTKILPERPPSAQDGLGSTRGP------------PSSLPQRHFPGQAYRASGVDTSPGPP 423 I E+ P+ + G GP P R PG G D PGPP Sbjct: 496 PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSP-GGPGSDGKPGPP 554 Query: 424 DT--ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQR-------L 474 + E PGPP P+ P +P P G A ++ G PG + Sbjct: 555 GSQGESGRPGPPGPSGPR-GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613 Query: 475 CLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--GSQGALGTAGKTPGPRE 532 PQ P P P G + L LP G P G G G G AG P Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673 Query: 533 KLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSE-- 590 K A + G P L G+ GA P + P G P + P E Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRG-GAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERG 732 Query: 591 ---SPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP 647 SP P G + P P P+ GP+GP P E G+P Sbjct: 733 GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPT-------GPIGPPGPAGQPGDKGEGGAP 785 Query: 648 -FPSPEPPHSLPTHY----QPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGL 702 P P P P PA FP G G E P E E G G+ Sbjct: 786 GLPGIAGPRGSPGERGETGPPGPA-GFPGAPGQNGEPGG---KGERGAPGEKGEGGPPGV 841 Query: 703 QGFP----RAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLA 758 G P A PP P R G A Sbjct: 842 AGPPGGSGPAGPPGP------------------------------QGVKGERGSPGGPGA 871 Query: 759 RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLP 818 G + PGPPG P P G + + GKD P Sbjct: 872 AGFPGARGLPGPPGSNGNPGPP--------------------GPSGSPGKDGP------- 904 Query: 819 SLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRG 878 P PA + + ++G + + P ++ G +G Sbjct: 905 -------PGPAGNTGAPG--------SPGVSGPKGDAGQP----------GEKGSPGAQG 939 Query: 879 PSSGHPLKSKAGVTPES--KAPP--PLPAATPDPQ-----TPRPGDRGCPA-RGRPKTRS 928 P AG+T PP P P +P PQ + +PG G RG P + Sbjct: 940 PPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG 999 Query: 929 L-GLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLG 987 L GLA T A GR G D +GS G G R P G Sbjct: 1000 LPGLAGT---AGEPGRDGNPGS---------DGLPGRDGSPGGKGDRGENGSPGAPGAPG 1047 Query: 988 ERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWG 1047 PP P P ++ G R + P P A P +R + P + PR K G G Sbjct: 1048 HPGPPGPVGPAGKS-GDRGESGPAGPAGAPGPAGSRGA-----PGPQGPRGDKGETGERG 1101 Query: 1048 KELILKIVQQKNRLREYDFASESEEDEQPPPRG-------PGFRGRRG----RGEKRKEV 1096 I F P P G PG G RG G K+ Sbjct: 1102 AAGI---------KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDG 1152 Query: 1097 ELTQG-PREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGP-SRSLETGA 1154 T G P P PR R E G +G+P +P +PG PGP P A GP + A Sbjct: 1153 --TSGHPGPIGPPGPR-GNRGERGSEGSPGHPGQPG--PPGP---PGAPGPCCGGVGAAA 1204 Query: 1155 AAREGGPKCADRPSVAPKDPLQVPTNTE 1182 A GG K +P+ NT+ Sbjct: 1205 IAGIGGEKAGGFAPYYGDEPMDFKINTD 1232 Score = 97.1 bits (240), Expect = 3e-19 Identities = 326/1305 (24%), Positives = 384/1305 (29%), Gaps = 303/1305 (23%) Query: 74 KPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTL 133 +PP+ GQ P G G P P P + PP GI S Sbjct: 97 RPPN--GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPP-----GICES------ 143 Query: 134 DETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTS 193 P PQ + Q D G G GL Sbjct: 144 --CPTGPQNYSPQYDSYDVKSGVAVG-----GL--------------------------- 169 Query: 194 TNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPA 253 Y P+ P P PGPP + G P PGS P YQ PG P+ Sbjct: 170 AGYPGPAGPPGP--PGPPGTSG-HPGSPGS-PGYQGP-------------PGEPGQAGPS 212 Query: 254 EPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313 P P P G+ P G + P G P P + G A G H+ Sbjct: 213 GP-PGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGR 271 Query: 314 PEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLH 373 E TG P + LP G PG + G PG +A +D Sbjct: 272 NGEKGETG----APGLKGENGLPGENGAPGPMGPRG-APGERGRPGLPGAAGARGNDGAR 326 Query: 374 KSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP 433 S DG GPP + FPG A G G P + APG Sbjct: 327 GS-------------DGQPGPPGPPGT---AGFPGSP-GAKGEVGPAGSPGSN-GAPGQR 368 Query: 434 PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTAR- 492 PQ P P PPG NG P + A +P L AR Sbjct: 369 GEPGPQGHAGAQGP-PGPPG----------INGSPGGKGEM---GPAGIPGAPGLMGARG 414 Query: 493 -PSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK-----LPAVRSSQG---- 542 P P G L AG P G GA G PGPR + +P V ++G Sbjct: 415 PPGPAGANGAPGLRGGAGEP----GKNGAKG----EPGPRGERGEAGIPGVPGAKGEDGK 466 Query: 543 -GSPALFTYNGMTDPGA-----QPLFFGVAQPQVSP--------HGTPSLPPPRVVGASP 588 GSP NG+ PGA P F G A P P G P PR P Sbjct: 467 DGSPGEPGANGL--PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEP 524 Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANP--SSEESQLPGPLGPSAFFHPPTHPQETGS 646 +P G S P S P S ES PGP GPS P P G Sbjct: 525 GRDGVPG-GPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG---PRGQPGVMG- 579 Query: 647 PFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFP 706 FP P+ P P P G G E P GP G GG +G Sbjct: 580 -FPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNG-----ETGPQGPPGP-TGPGGDKGDT 632 Query: 707 RAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQR 766 P P G ++G Sbjct: 633 GPPGPQGLQGLP-----------------------------------GTGGPPGENGKPG 657 Query: 767 SPGPPGLPSPPAAPRVPADAHA-------------GLLSHAKTFLLAGDAQAEGKDDPLR 813 PGP G P AP DA A GL A G A G P Sbjct: 658 EPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPG 717 Query: 814 TGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEP 873 P L P + L + G + + P D V + P Sbjct: 718 AAGTPGLQGMP-------------GERGGLGSPGPKGDKGEPGGPGADG----VPGKDGP 760 Query: 874 SGPRGP-----SSGHPLKSKAGVTP--------------ESKAPPPLPAATPDP--QTPR 912 GP GP +G P G P + PP PA P Q Sbjct: 761 RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE 820 Query: 913 PGDRGCPARGRPKTRSLGLAPTEADAP-SQGRQQRRGKQ-LKLFRKDLDSGGAAEGSGSG 970 PG +G RG P + G P A P G G Q +K R GAA G+ Sbjct: 821 PGGKG--ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGAR 878 Query: 971 G-----GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSS 1025 G G + P + G+ PP P T APGS P+ A P E S Sbjct: 879 GLPGPPGSNGNPGPPGPSGSPGKDGPPGP-AGNTGAPGSPGVSGPK--GDAGQPGEKGSP 935 Query: 1026 RRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG-PGFR 1084 + P P GA G + P PRG PG + Sbjct: 936 GAQGPPGAPGPLGIAGITGARGL---------------------AGPPGMPGPRGSPGPQ 974 Query: 1085 GRRGRGEKRKEVELT--QGPREDEPQKPRKAARQEAGGDGAPANPEEPG--GSRPGPGRS 1140 G +G K L+ +GP + E G DG P + PG GS G G Sbjct: 975 GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034 Query: 1141 PQARGPSRSLETGAAAREGGP-------KCADRPSVAPKDPLQVPTNTETSEETRPSLDF 1193 + P GA G P K DR P P P P Sbjct: 1035 GENGSPG---APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAP--GPAGSRGAPGPQG 1089 Query: 1194 PQEAKEPETAEESAPDSTEFTEALRSPPA----ACAGEMGA--SPGLLIPEQP-----PP 1242 P+ K ET E A +P A AG+ GA SPG P P PP Sbjct: 1090 PRGDK-GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP 1148 Query: 1243 SRHDT----GTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283 + T G P G N GS +PG G PG AP Sbjct: 1149 GKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAP 1193 Score = 92.8 bits (229), Expect = 6e-18 Identities = 332/1377 (24%), Positives = 411/1377 (29%), Gaps = 354/1377 (25%) Query: 140 PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSP 199 P + P PQGP G P PG+P P P Sbjct: 91 PPTAPTRPPNGQGPQGP-KGDPGPPGIPGRNGDPGI-----------------------P 126 Query: 200 SATPRPPAPGPPQSRGTSPLQPGSY-PEYQASGADSWPPAAENS-FPGANFGVPPAEPEP 257 P +PGPP + P P +Y P+Y + S + +PG PP P P Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGP--AGPPGPPGP 184 Query: 258 IPKGSRPGGSPRGVSFQFP--FPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPE 315 PG SP +Q P P G S P P G +GP + P Sbjct: 185 PGTSGHPG-SPGSPGYQGPPGEPGQAGPSGPPGPPGAIG---PSGPAGKDGESGRPGRPG 240 Query: 316 EAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAPRPFSDSLH 373 E GP P P+ +P + G G G + + G +PG Sbjct: 241 ERGLPGP----PGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGL------------- 283 Query: 374 KSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYR-----ASGVDTSPGPPDTELA 428 ++GL G P + R PG+ R A+G + G ++ Sbjct: 284 ------------KGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD-G 330 Query: 429 APGPPPARLPQLWDPTAAPYPTPPG--GPLAATRSMFFNGQPSPGQR-LCLPQS-APLPW 484 PGPP P A +P PG G + S NG +PGQR PQ A Sbjct: 331 QPGPPGP-------PGTAGFPGSPGAKGEVGPAGSPGSNG--APGQRGEPGPQGHAGAQG 381 Query: 485 PQVLPTARPSPHGMEMLSRLPFP-------AGGPEWQGGSQGALGTAGKT---------- 527 P P SP G + P A GP G+ GA G G Sbjct: 382 PPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKG 441 Query: 528 -PGPREK-----LPAVRSSQG-----GSPALFTYNGMTDPGAQ-----PLFFGVAQPQVS 571 PGPR + +P V ++G GSP NG+ PGA P F G A P Sbjct: 442 EPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL--PGAAGERGAPGFRGPAGPNGI 499 Query: 572 P--------HGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623 P G P PR P +P + M SP P S+ Sbjct: 500 PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP---------GMRGMPGSPGGPGSDGK 550 Query: 624 QLPGPLGPSAFFHPPTHPQETGSPFP-SPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAF 682 PGP G E+G P P P P P FP P GA G Sbjct: 551 --PGPPGSQG---------ESGRPGPPGPSGPRGQPG------VMGFPGPKGNDGAPGKN 593 Query: 683 QCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSS 742 P G+ G G P+ PP PT D+ D Sbjct: 594 GERGGPGGPGPQGPPGKNGETG-PQGPPG-PT------GPGGDKGDT------------- 632 Query: 743 LAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGD 802 G + G + GPPG P P DA A K GD Sbjct: 633 -----------GPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK-----GD 676 Query: 803 AQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDS 862 A A G+ P P LA P L G Sbjct: 677 AGAPGERGP------PGLAGAP----------------------GLRG------------ 696 Query: 863 SFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARG 922 +GP GP G G PP A TP Q PG+RG Sbjct: 697 ----------GAGPPGPEGGKGAAGPPG--------PPGAAGTPGLQG-MPGERGGLGSP 737 Query: 923 RPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR--- 979 PK AD G+ RG + G A G G G A GL Sbjct: 738 GPKGDKGEPGGPGADGVP-GKDGPRGPT-----GPIGPPGPAGQPGDKGEGGAPGLPGIA 791 Query: 980 -PRRNDG-LGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPR 1037 PR + G GE PP P APG +P + R A P E P P Sbjct: 792 GPRGSPGERGETGPPGPAG-FPGAPGQNGEPGGKGERGA--PGEKGEGGP---PGVAGPP 845 Query: 1038 KRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPG---FRGRRGRGEKRK 1094 G G + + + E+ P GPG F G RG Sbjct: 846 GGSGPAGPPGPQGV--------------------KGERGSPGGPGAAGFPGARGLPGPPG 885 Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPG----GSRPGPGRSPQARGPSRSL 1150 GP + AG GAP +P G +PG SP A+GP + Sbjct: 886 S-NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAP 944 Query: 1151 E-------TGAAAREG-----GPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAK 1198 TGA G GP+ + P + + N + E P PQ Sbjct: 945 GPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG---PQGLP 1001 Query: 1199 E-PETAEESAPDSTEFTEAL--RSPPAACAGEMGAS-----------PGLLIPEQPPPSR 1244 TA E D ++ L R G+ G + PG P P Sbjct: 1002 GLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKS 1061 Query: 1245 HDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVA 1304 D G P+G P GS P GP G + + A G P Sbjct: 1062 GDRGESGPAGPAGAPGPAGSRGAP-------GPQGPRGDKGETGERGAAGIKGHRGFP-G 1113 Query: 1305 NPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGV--PVAKKG----PQPYSSPHSELFLG 1358 NP + P P+ I S G PAG R P+G P K G P P P G Sbjct: 1114 NPGAPGSPGPAGQQGAIGSPG--PAG-PRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRG 1170 Query: 1359 PKDLAGCFLEELHPKPSARDAPPASSSCLCQ----------DGEDAGSLEPQLPRSP 1405 + G HP PP + C GE AG P P Sbjct: 1171 ERGSEG---SPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEP 1224 Score = 81.3 bits (199), Expect = 2e-14 Identities = 208/834 (24%), Positives = 252/834 (30%), Gaps = 189/834 (22%) Query: 1 MPGER-------PRGAPP----PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAR 49 +PGE PRGAP P + G R + G QP P T G+ Sbjct: 289 LPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPG-PPGPPGTAGFPGSP 347 Query: 50 EAGGQAQAMELPEAQPRQARDGELKPPSLRG-QAPSSTPGKRGSP--------------- 93 A G+ P + + GE P G Q P PG GSP Sbjct: 348 GAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407 Query: 94 -----QTPPGRSPLQAPSRLAGRA--------EGSPPQRY------ILGIASSRTKPTLD 134 + PPG + L G A +G P R I G+ ++ + D Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467 Query: 135 ETPENPQLEAAQLPEVDTPQG-PGTGAPLRPGLPRTEAQPAAEE-----LGFHRCFQEPP 188 +P P A LP +G PG P P E PA E G EP Sbjct: 468 GSPGEPG--ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525 Query: 189 SSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANF 248 P P +PG P S G P PGS E G PP P Sbjct: 526 RDGVPGG---PGMRGMPGSPGGPGSDG-KPGPPGSQGESGRPG----PPG-----PSGPR 572 Query: 249 GVPPAEPEPIPKGS--RPG-----GSPRGVSFQFPFPALHGASTK---PFPADVAGHAFT 298 G P P PKG+ PG G P G Q P P +G + P P G Sbjct: 573 GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP-PGKNGETGPQGPPGPTGPGGDKGD 631 Query: 299 NGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQPGGLNRHSDLSGALSS 357 GP PQG G P P +P P G PGG + G Sbjct: 632 TGP-----PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG-DAGAPGERGP 685 Query: 358 PGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTR--GPPSSLPQRHFPGQAYRASG 415 PG A AP + PP + G G+ GPP + G G Sbjct: 686 PGLA-GAPGLRGGA-----------GPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733 Query: 416 VDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLC 475 + SPGP + GP +P P P P GP G P Sbjct: 734 LG-SPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG------ 786 Query: 476 LPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLP 535 LP A P P G GP G GA G G+ G E+ Sbjct: 787 LPGIAG-------PRGSPGERGET----------GPPGPAGFPGAPGQNGEPGGKGERGA 829 Query: 536 AVRSSQGGSPALFTYNGMTDPGAQPLFFGV-----------------AQPQVSPHGTPSL 578 +GG P + G + P P GV A+ P G+ Sbjct: 830 PGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGN 889 Query: 579 PPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-------LPGPL-- 629 P P SP + P PA NT +S P + S PGPL Sbjct: 890 PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949 Query: 630 ----GPSAFFHPPTHPQETGSPFP-------------------SPEPPHSLP--THYQPE 664 G PP P GSP P P P LP E Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009 Query: 665 PAKAFPFPADGL-GAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP----PPYP 713 P + +DGL G +G+ P + G G G P AP PP P Sbjct: 1010 PGRDGNPGSDGLPGRDGS---------PGGKGDRGENGSPGAPGAPGHPGPPGP 1054 Score = 74.7 bits (182), Expect = 2e-12 Identities = 217/902 (24%), Positives = 274/902 (30%), Gaps = 155/902 (17%) Query: 649 PSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRA 708 P+PE P P+P A P +G G +G P + G G G P + Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134 Query: 709 PPP------YPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKD 762 P P PT + S D DV + LA + G Sbjct: 135 PGPPGICESCPTGPQNYSP-QYDSYDV-----KSGVAVGGLAGYPGPAGPPGPPGPPGTS 188 Query: 763 GHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAA 822 GH SPG PG PP P AG G + GKD P Sbjct: 189 GHPGSPGSPGYQGPPGEP-----GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243 Query: 823 TPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSG 882 P P + G + D +G +G + Sbjct: 244 LPGPPGIKG-------------PAGIPGFPGMKGHRGFDGR----------NGEKGETGA 280 Query: 883 HPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCP-ARGRPKTRSLGLAPTEADAPSQ 941 LK + G+ E+ AP P+ + RPG G ARG R P P Sbjct: 281 PGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT 340 Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR--PRRNDGLGERPPPRPRRPRT 999 F + G +GS G A G R P G + PP P Sbjct: 341 AG----------FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING 390 Query: 1000 QAPGSRADPAPR-VPRAAAL--------PEETRSSRRRRLPPRKDPRKRKARG-----GA 1045 +PG + + P +P A L P + R +P K A+G G Sbjct: 391 -SPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLR-GGAGEPGKNGAKGEPGPRGE 448 Query: 1046 WGKELILKIVQQKNRLREYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQG 1101 G+ I + K + E + P G PGFRG G E +G Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE----KG 504 Query: 1102 PREDE----PQKPRKAARQEAGGDGAPANPEEPG--GSRPGPGRSPQARGPSRSLETGAA 1155 P + P PR AA E G DG P P G GS GPG + P E+G Sbjct: 505 PAGERGAPGPAGPRGAAG-EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP 563 Query: 1156 AREGGPKCADRPSV----APKDPLQVPTNTETSEETRPSLDFPQ--EAKEPETAEESAPD 1209 G +P V PK P + E P PQ K ET + P Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPG--KNGERGGPGGPGPQGPPGKNGETGPQGPPG 621 Query: 1210 STEFTEALRSPPAACAGEMGAS-----PGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGS 1264 T P G+ G GL PP G P P G G Sbjct: 622 PTG--------PGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673 Query: 1265 SPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLA-PVANPSSTACPKPSVLSSKISS 1323 G G PG AP PP + G+ A P P + P + + Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733 Query: 1324 FGC--------DPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPS 1375 G +P G D GVP K GP+ + P +GP AG P Sbjct: 734 LGSPGPKGDKGEPGGPGAD--GVP-GKDGPRGPTGP-----IGPPGPAG------QPGDK 779 Query: 1376 ARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGT-AETEPGRAASPPTLESSSLFPDLPVD 1434 P AG PR PG ET P A FP P Sbjct: 780 GEGGAPGLPGI-------AG------PRGSPGERGETGPPGPAG---------FPGAPGQ 817 Query: 1435 RFDPPLYGSLSA--NRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLP--SHFPDL 1490 +P G A + G P A PP + P+ PP P + E SP P + FP Sbjct: 818 NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA 877 Query: 1491 SG 1492 G Sbjct: 878 RG 879 Score = 73.2 bits (178), Expect = 5e-12 Identities = 232/966 (24%), Positives = 302/966 (31%), Gaps = 201/966 (20%) Query: 1622 VQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQ 1681 + G PGG + PG L+ P P GAN P + GA + G Sbjct: 388 INGSPGGKGEMGPAGIPGAPGLMGAR-------GPPGPAGANG--APGLRGGAGEPGKNG 438 Query: 1682 AEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLP 1741 A+G+ PGP+ + G E P + ED P Sbjct: 439 AKGE---------------PGPRGERG---------EAGIP----GVPGAKGEDGKDGSP 470 Query: 1742 CEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSH 1801 E LP G A + RGAP F PA P+ G+ P + P A P Sbjct: 471 GEPGANGLP--GAAGE--RGAPG---FRGPA---GPN-GIPGEKGPAGERGAPGPAGPRG 519 Query: 1802 AA--QGHSAGRAGGHLHPTAGRPGFEGNEFAPA-----GASSLTAPRGREAWLVPVPSPA 1854 AA G G + G PG G++ P G S P G P P Sbjct: 520 AAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG---PRGQPG 576 Query: 1855 CVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQ----ELTPAAQS----PPR 1906 + P P + PGP K+G G Q P PP Sbjct: 577 VMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPP- 635 Query: 1907 VNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQG 1966 P GL+G GG G PG P G + A G G G A Sbjct: 636 -GPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL 694 Query: 1967 QGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEP 2026 +G A PE G G +P G + KG + A+ Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG-GPGADG 753 Query: 2027 TPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACA 2086 P P + + + G +G +PGL P +A P S G+ Sbjct: 754 VPGKDGPRGPTGPIGPPGPAGQPGDKG----EGGAPGL--PGIA---GPRGSPGERGETG 804 Query: 2087 -PSPTSAAHMPCSLGP--------LPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137 P P P G P E P G GG PA PPGPQ + Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG-----PPGPQGV 859 Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDP 2197 G A GA P PP +P P + GSP +D Sbjct: 860 K------GERGSPGGPGAAGFPGARGLP-GPPGSNGNPGPPGPS---------GSPGKDG 903 Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257 P G+ A P + P+ + PG SP GA P A Sbjct: 904 PPGPAGNTGA---------PGSPGVSGPKGDAGQ-----PGEKGSP---GAQGPPGAPGP 946 Query: 2258 TGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRG--HSSYSPSNTARLGHREG 2314 G++ TG AG G+PGP RG+P P+G S P G R Sbjct: 947 LGIAGI-TGARGLAGPPGMPGP----RGSPG-------PQGVKGESGKPGANGLSGER-- 992 Query: 2315 QAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTG 2374 GP P L G GT+ + D G G+ +P Sbjct: 993 ----------------GPPGPQGLPGLAGTAGEPGRD------GNPGSDGLP-------- 1022 Query: 2375 LGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTEN-- 2432 GR +P ++ SP + H P G P+GP K RG + PA Sbjct: 1023 ---GRDGSPGGKGDRGENGSPGAPGAPGHPGPPG-PVGPAG-KSGDRG-ESGPAGPAGAP 1076 Query: 2433 ---GQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA----ALPAQ 2485 G P GP + R G+ H R +PGAP P PA A+ + Sbjct: 1077 GPAGSRGAPGPQGP-RGDKGETGERGAAGIKGH--RGFPGNPGAPGSPGPAGQQGAIGSP 1133 Query: 2486 QPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSP-HSQQ 2544 P P + SG + + G P + PP +G++ + GSP H Q Sbjct: 1134 GPAGP---------RGPVGPSGPPGKDGTSGHPGPI-GPPGPRGNRGERGSEGSPGHPGQ 1183 Query: 2545 LHPPSP 2550 PP P Sbjct: 1184 PGPPGP 1189 Score = 68.9 bits (167), Expect = 9e-11 Identities = 259/1075 (24%), Positives = 333/1075 (30%), Gaps = 206/1075 (19%) Query: 480 APLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG-----GSQGALGTAGKTPGPREKL 534 A P P PT P+ G + P P G P G G G+ G+ G PG E Sbjct: 86 AVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGP-PGICESC 144 Query: 535 PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLP 594 P Q SP +Y+ + GVA ++ + P+ PP P P Sbjct: 145 PT--GPQNYSPQYDSYDVKS---------GVAVGGLAGYPGPAGPP------GPPGPPGT 187 Query: 595 SPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHP------PTHPQETGSPF 648 S + GS P A PS PG +GPS P P E G P Sbjct: 188 SGHPGSPGSPGYQGPPGEPGQAGPSGPPGP-PGAIGPSGPAGKDGESGRPGRPGERGLPG 246 Query: 649 PSP-EPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHE-------GP----- 695 P + P +P + + F G GA E P E GP Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306 Query: 696 EVGRGGLQGF---------------PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNY 740 E GR GL G P P P T F S + ++ Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGP----------- 355 Query: 741 SSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLA 800 A G GH + GPPG P +P G + A Sbjct: 356 ---AGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSP-----GGKGEMGPAGIPGAP 407 Query: 801 GDAQAEGKDDPLRTGFLPSL----------AATPFPLPASDLDMEDDAKLDSLITEALNG 850 G A G P P L A P P + +A + + G Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE---RGEAGIPGV--PGAKG 462 Query: 851 MEYQSDNP-EIDSSFIDVFADEEPS-GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDP 908 + + +P E ++ + A E + G RGP+ + + + G E AP P A P Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP---AGPRG 519 Query: 909 QTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFR------------- 955 PG G P G P R G+ + S G+ G Q + R Sbjct: 520 AAGEPGRDGVP--GGPGMR--GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575 Query: 956 --------KDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRAD 1007 K D G G GG P +N G + PP P P G + D Sbjct: 576 GVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG----GDKGD 631 Query: 1008 PAPRVPRAA-ALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKN------- 1059 P P+ LP P P+ GA G + ++ Sbjct: 632 TGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGA 691 Query: 1060 ---RLREYDFASESEEDEQPPPRGPGFRGRRG-RGEKRKEVEL-TQGPREDEPQKPRKAA 1114 R E + PP PG G G +G + L + GP+ D+ + A Sbjct: 692 PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751 Query: 1115 RQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLET-GAAAREGGPKCADRPSVAPKD 1173 G DG P P P G PGP P +G + G A G P +R P Sbjct: 752 DGVPGKDG-PRGPTGPIGP-PGPAGQPGDKGEGGAPGLPGIAGPRGSP--GERGETGPPG 807 Query: 1174 PLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSP-----PAACAGEM 1228 P P + E E P E P P P GE Sbjct: 808 PAGFPGAPGQNGEPGGK----GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863 Query: 1229 GASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNS 1288 G SPG P +R G P P GS N P G S +PG G G T AP S Sbjct: 864 G-SPGGPGAAGFPGAR---GLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGV 919 Query: 1289 KDP--PARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQ 1346 P A QPGE +P A P P ++ + G AG P G+P + P Sbjct: 920 SGPKGDAGQPGEKGSPGAQ-GPPGAPGPLGIAGITGARGL--AG----PPGMPGPRGSPG 972 Query: 1347 PYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPP 1406 P G K +G KP A +G P P+ P Sbjct: 973 PQ---------GVKGESG--------KPGANGL--------------SGERGPPGPQGLP 1001 Query: 1407 GTAET--EPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADP 1459 G A T EPGR +P + LP P G N G P A P Sbjct: 1002 GLAGTAGEPGRDGNPGS-------DGLPGRDGSPGGKGDRGENGSPGAPGAPGHP 1049 Score = 67.0 bits (162), Expect = 3e-10 Identities = 264/1160 (22%), Positives = 352/1160 (30%), Gaps = 233/1160 (20%) Query: 1119 GGDGAPANPEEPGGSRP-GPGRSPQARGPS----RSLETGAAAREGGPKCADRPSVAPKD 1173 G G P EPG + P GP P A GPS + E+G R G P + K Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGI--KG 252 Query: 1174 PLQVPTNTETSEETRPSLDFPQ-------EAKEPETAEESAPDSTEFTEALRSPPAACAG 1226 P +P FP + + E E AP G Sbjct: 253 PAGIP-------------GFPGMKGHRGFDGRNGEKGETGAPGL--------KGENGLPG 291 Query: 1227 EMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSH 1286 E GA PG + P P R G P +G+ N GS PG G PG P S Sbjct: 292 ENGA-PGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP---GPPGTAGFPGSP 347 Query: 1287 NSKDPPARQPGEFLAPVANPSSTACP----KPSVLSSKISSFGCDPAGFNRDPLGVPVAK 1342 +K GE + P +P S P +P + P G N G P K Sbjct: 348 GAK-------GE-VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN----GSPGGK 395 Query: 1343 KGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLP 1402 P P + +G + P P+ + P + G++ EP P Sbjct: 396 GEMGPAGIPGAPGLMGARG---------PPGPAGANGAPGLRGGAGEPGKNGAKGEPG-P 445 Query: 1403 RSPPGTA--------ETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF 1454 R G A + E G+ SP ++ L P +R P G N G+P Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL-PGAAGERGAPGFRGPAGPN---GIPG 501 Query: 1455 ACADPPQKTVPSDPPYPSFLLLEEVSPMLPSH-----FPDLSGGKVLSKTCPPERTVVPG 1509 ++ P P P E +P P GG P + Sbjct: 502 EKGPAGERGAPG-PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560 Query: 1510 AAPSLPG-KGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGR 1568 P PG G +M K GAP + E G Sbjct: 561 GRPGPPGPSGPRGQPGVMG-------------------FPGPKGNDGAPGKNGERGGPG- 600 Query: 1569 VELGTGTE-PPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPG 1627 G G + PP + P T D G + +QG PG Sbjct: 601 ---GPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP------------QGLQGLPG 645 Query: 1628 GTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSR 1687 P + PG P + D +GAP +P G P ++ G G + Sbjct: 646 TGGPPGENGKPGE----PGPKGD--AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAG 699 Query: 1688 PPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSF-----PKNKEAASSQESEDSLRLLPC 1742 PP + PGP AG+ E PK + D + P Sbjct: 700 PPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV---PG 756 Query: 1743 EQ--RG--GFLPEPGTADQP----HRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWP 1794 + RG G + PG A QP GAP P +G+ PP A +P Sbjct: 757 KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE----RGETGPPGPAGFP 812 Query: 1795 FGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPA 1854 GA + G R G PG G P G S P P P Sbjct: 813 -GAPGQNGEPGGKGERGAPGEKGEGGPPGVAG----PPGGSGPAGP----------PGPQ 857 Query: 1855 CVSNTHPSRRSQDPALSPPIRQLQ----------LPGPGVAKSKDGILGLQELTPAAQSP 1904 V S A P R L PGP + KDG G T A SP Sbjct: 858 GVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSP 917 Query: 1905 PRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAG--HQLGLE----ADGHWGLL 1958 P G G E G G+PG + + + G G+ + G G+ Sbjct: 918 GVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK 977 Query: 1959 GQAEKTQGQGTANQLQPENGVS-PG--GTDNHASVNASPKTALTGPTEGAVLLEKCKGSR 2015 G++ K G + + P PG GT + +P + +G+ + +G Sbjct: 978 GESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN 1037 Query: 2016 AAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSP 2075 + A P PP P G G++ +R S P Sbjct: 1038 GSPG-APGAPGHPGPPGP---------------VGPAGKSGDRGES------------GP 1069 Query: 2076 APSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQ--LPASPSCRDPPG 2133 A G AP P + P G PR D + R G+ G P +P PG Sbjct: 1070 AGPAG-----APGPAGSRGAPGPQG--PRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG 1122 Query: 2134 P--QQLLACSPAWA----PLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLL 2187 P QQ SP A P+ + G T P+ PP + + Sbjct: 1123 PAGQQGAIGSPGPAGPRGPVGPS-GPPGKDGTSGHPGPIGPPGPRGNRGE---------R 1172 Query: 2188 QGEGSPLEDPSSWPPGSVSA 2207 EGSP PPG A Sbjct: 1173 GSEGSPGHPGQPGPPGPPGA 1192 Score = 65.9 bits (159), Expect = 8e-10 Identities = 290/1235 (23%), Positives = 372/1235 (30%), Gaps = 247/1235 (20%) Query: 1683 EGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQEL-SFPKNKEAASSQESEDSLRLLP 1741 +GD PP +P + PG GS P S P + S Q DS + Sbjct: 108 KGDPGPPG---IPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQY--DSYDVKS 162 Query: 1742 CEQRGGFLPEPGTADQPHRGAPA-----PEAFGSPAVHLAPDLAFQGDGAPPLDATWPFG 1796 GG PG A P P P + GSP P Q + P G Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG 222 Query: 1797 ASPSHAAQGHSA--GRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGR----------- 1843 S G S GR G P G PG +G PAG +G Sbjct: 223 PSGPAGKDGESGRPGRPGERGLP--GPPGIKG----PAGIPGFPGMKGHRGFDGRNGEKG 276 Query: 1844 EAWLVPVPSPACVSNTHPSRRSQDPALSPPIR-QLQLPGPGVAKSKDGILGLQELTPAAQ 1902 E + + + + P +P R + LPG A+ DG G + P Sbjct: 277 ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG-SDGQPGPP 335 Query: 1903 SPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAE 1962 PP +G G G+V + GS G P GH G G+ G Sbjct: 336 GPP--GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPG 393 Query: 1963 KTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQE 2022 G A + G A N +P L G A + Sbjct: 394 GKGEMGPAGIPGAPGLMGARGPPGPAGANGAP--GLRG--------------GAGEPGKN 437 Query: 2023 EAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDL 2082 A+ P P E+ + A G +G E PG N A G+ AP Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGE----PGANGLPGAAGERGAPGF--- 490 Query: 2083 AACAPSPTSAAHMPCSLGPL-PREDPLTSPSRAQGGLGGQ--LPASPSCRDPPGPQQLLA 2139 P +P GP R P + R G G+ +P P R PG Sbjct: 491 ----RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPG------ 540 Query: 2140 CSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSS 2199 SP +DG + E PP P P+ G P Sbjct: 541 -SPGG---PGSDGKPGPPGSQGESGRPGPP----GPSGPR-----------GQPGVMGFP 581 Query: 2200 WPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATG 2259 P G+ A P + + PG P G P TG Sbjct: 582 GPKGNDGA-----------------PGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG 624 Query: 2260 LSSTPTGDEAQAG-------RGLPGPDPQSRGAPPHTN---PDRMPRGHSSY--SPSNTA 2307 P GD+ G +GLPG G PP N + P+G + +P Sbjct: 625 ----PGGDKGDTGPPGPQGLQGLPG-----TGGPPGENGKPGEPGPKGDAGAPGAPGGKG 675 Query: 2308 RLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPR 2367 G + + P GAGP P EG G + PG P G +G + Sbjct: 676 DAGAPGERGPPGLAGAPGLRGGAGPPGP---EGGKGAAG----PPGPP--GAAGTPGLQG 726 Query: 2368 VTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQG--DPLGPQDLKQRSRGYKK 2425 + GLG +P + P + P+G P+GP Sbjct: 727 MPGERGGLG-----SPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPG---------- 771 Query: 2426 KPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQ 2485 PA + +G AP P A R PG G P PA P Sbjct: 772 -PAGQPGDKGEGGAPGLP-----GIAGPRGSPG-----------ERGETGPPGPAGFPGA 814 Query: 2486 QPLEPLAQKCQPPRKKSHRVSGKE---RPNHSRGDP--SHVTQPPPAQGSKEVLRAPGS- 2539 Q +P K G++ P G P S PP QG K +PG Sbjct: 815 P-----GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869 Query: 2540 -----PHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVD 2594 P ++ L P + P+ P D P G P V Sbjct: 870 GAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD-------GPPGPAGNTGA--PGSPGVS 920 Query: 2595 SPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAAS--PSHCLS 2652 P G+ +K G + + P+ I+ RG P M S P Sbjct: 921 GPKGDAGQPGEKGSP--GAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKG 978 Query: 2653 VEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAAL 2712 G P A+G R GP + G A T AGE G PG L PGR DG+ Sbjct: 979 ESGKPGANGLSGER-GPPGPQGLPGLAGT------AGEPGRDGNPGSDGL-PGR-DGSPG 1029 Query: 2713 GEQPTGQKGA-SARGFWG-PRETKALGVCKESGSE-------PAEDSSRAHSRSEEGVWE 2763 G+ G+ G+ A G G P +G +SG PA A SR G Sbjct: 1030 GKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG--- 1086 Query: 2764 ENTPPLGPLGFP-ETSSSPADSTTSSCLQGLPDNPDTQG--------------GVQGPEG 2808 P GP G ET A +G P NP G G GP G Sbjct: 1087 ----PQGPRGDKGETGERGAAGIKGH--RGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRG 1140 Query: 2809 PTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTR 2843 P SG KD S + PPG R R Sbjct: 1141 PV-GPSGPPGKDGTSGHPGPIG-----PPGPRGNR 1169 Score = 63.2 bits (152), Expect = 5e-09 Identities = 107/414 (25%), Positives = 146/414 (35%), Gaps = 66/414 (15%) Query: 3428 PGAPGQKARAL---EGTLPSKRRRVAMPGSAPGPGEDRPP-PRGSSPILSEGSLPALLHL 3483 PGAPGQ E P ++ PG A PG P P G + E P Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG---- 867 Query: 3484 CSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNH--QECPPPSL----SPFPAALADG 3537 P G+P P P ++ G PS ++ PP +P ++ Sbjct: 868 ----GPGAA-GFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922 Query: 3538 RGDCALDGALERPENEASPGSPGPLLQQAL--------PLGASLPR--PGARGQDAE-GK 3586 +GD G P + PG+PGPL + P G PR PG +G E GK Sbjct: 923 KGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK 982 Query: 3587 RAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA 3646 SG+R PG +G ++ +G P G P Sbjct: 983 PGANGLSGERGPPGPQGLPG-------------LAGTAGEPGRDGNPGSDGLPGRDGSPG 1029 Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGTENGMKPATPKAKPGPS-S 3704 G DR +P A P HP G + P G+ E+G PA P PGP+ S Sbjct: 1030 G----KGDRGENGSPG-APGAPGHPGPP-GPVGPAGKSGDRGESG--PAGPAGAPGPAGS 1081 Query: 3705 QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG 3764 +G+ P+ G + + A+G FP AP P A + Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAG--------IKGHRGFPGNPGAPGS-PGPAGQQGAIGS 1132 Query: 3765 PREAGEQGPHGSLGPKEKGESSTKRKKGQV--PGPARSESVGSFGRAPSAPDKP 3816 P AG +GP G GP G+ T G + PGP + +P P +P Sbjct: 1133 PGPAGPRGPVGPSGP--PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184 Score = 60.5 bits (145), Expect = 3e-08 Identities = 126/515 (24%), Positives = 154/515 (29%), Gaps = 75/515 (14%) Query: 3415 GGRQPFAFRGVRRPGAPG-QKARALEGTL-----PSKRRRVAMPGSAPGPGEDRPPPRGS 3468 GG+ G+ PGAPG AR G P R PG GE P PRG Sbjct: 393 GGKGEMGPAGI--PGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE--PGPRGE 448 Query: 3469 SPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLS 3528 E +P + E + G P P G P+ P Sbjct: 449 R---GEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEK-- 503 Query: 3529 PFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLG-ASLPRPGARGQDAE-GK 3586 PA G GA P + PG PG P G S +PG G E G+ Sbjct: 504 -GPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGR 562 Query: 3587 RAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA 3646 P SG R PG G P K + + GGP G +G K Sbjct: 563 PGPPGPSGPRGQPGVMGFPGP----------KGNDGAPGKNGERGGPGGPGPQGPPGKNG 612 Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA----PGELARGTENGMK-----PATPK 3697 K P P+ G PGE + E G K P P Sbjct: 613 ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG 672 Query: 3698 AKPGPSSQGSGSP-----RPGTKTGGGSQPQPASGQLQSE------TATTPAKPSFPSR- 3745 K + G P PG + GG P P G+ + A TP P Sbjct: 673 GKGDAGAPGERGPPGLAGAPGLR-GGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGER 731 Query: 3746 ----SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPG-PARS 3800 SP P+ P + G +GP G +GP + +G PG P + Sbjct: 732 GGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791 Query: 3801 ESVGSFGR----APSAPDKPPRTPRKQATP----SRVLPTKP----------KPNSQNKP 3842 GS G P P P P + P R P + P Sbjct: 792 GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPA 851 Query: 3843 RPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPP 3877 PP + K E G G FP R L PP Sbjct: 852 GPPGPQGVKGERGSPGGPGAAG--FPGARGLPGPP 884 Score = 58.9 bits (141), Expect = 9e-08 Identities = 121/501 (24%), Positives = 164/501 (32%), Gaps = 92/501 (18%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPG------SAPGPGEDRPPPRGSSPILSEGSLPALL 3481 PG PG R + +P + PG S P ++ P S + S ++ L Sbjct: 111 PGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLA 170 Query: 3482 HLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDC 3541 P G P T P P + +G P PS P P G Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQG---PPGEPGQAGPSGPPGPPGAIGPSGPA 227 Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR-PGARG-QDAEGKRAPLVFSGKRRAP 3599 DG RP G PGP + A +P PG +G + +G+ G+ AP Sbjct: 228 GKDGESGRPGRPGERGLPGP---PGIKGPAGIPGFPGMKGHRGFDGRNGE---KGETGAP 281 Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGT-FHKGSATKPAGCQSSSKDRSAA 3658 G +G ++ L E GPRG +G P + D + Sbjct: 282 GLKG---------ENGLPGENGAPGPM-----GPRGAPGERGRPGLPGAAGARGNDGARG 327 Query: 3659 ST-------PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPR 3711 S P FP P A G + P G+ + +PGP Sbjct: 328 SDGQPGPPGPPGTAGFPGSP-GAKGEVGPA----GSPGSNGAPGQRGEPGPQGHAGAQGP 382 Query: 3712 PGT-----KTGGGSQPQPAS--GQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG 3764 PG GG + PA G A P P+ + +P R A K+ KG Sbjct: 383 PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPG-LRGGAGEPGKNGAKG 441 Query: 3765 -PREAGEQGPHGSLG-PKEKGESSTKRKKGQ-----VPGPARSESVGSFGRAPSAP---- 3813 P GE+G G G P KGE G+ +PG A F R P+ P Sbjct: 442 EPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGF-RGPAGPNGIP 500 Query: 3814 -DKPPRTPRKQATPS--------------------RVLPTKP-KPNSQNKPRPPPSEQRK 3851 +K P R P+ R +P P P S KP PP S+ Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560 Query: 3852 AEPGHTQRKDRLGKAFPQGRP 3872 PG G + P+G+P Sbjct: 561 GRPGPP------GPSGPRGQP 575 Score = 56.2 bits (134), Expect = 6e-07 Identities = 131/525 (24%), Positives = 165/525 (31%), Gaps = 91/525 (17%) Query: 3415 GGRQPFAFRGVRRPGAP-GQKARALEGTLPSKRRRVAMPGSAPGPGED-RPPPRGSSPIL 3472 G + P RG P P G +P MPGS GPG D +P P GS Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ--- 557 Query: 3473 SEGSLPALLHLCSEVAPSTTKGWPETLERPVD------PVTHPIRGCELPSNHQECPP-- 3524 E P PS +G P + P P + RG Q P Sbjct: 558 GESGRPG------PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKN 611 Query: 3525 ----PSLSPFPAALADGRGDCA---------LDGALERPENEASPGSPGPLLQQALPLGA 3571 P P P +GD L G P PG PGP P GA Sbjct: 612 GETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP-GA 670 Query: 3572 SLPRPGARGQ-DAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEK----EVSSSH 3626 PG +G A G+R P +G APG RG P + + Sbjct: 671 ----PGGKGDAGAPGERGPPGLAG---APGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPG 723 Query: 3627 MVSEGGPRGTFH----KGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGE 3682 + G RG KG +P G D + P+ P G PG+ Sbjct: 724 LQGMPGERGGLGSPGPKGDKGEPGG---PGADGVPGKDGPRGPTGPIGPPGPAGQ--PGD 778 Query: 3683 LARGTENGMKP-ATPKAKPGPSSQGSGSPRP----------GTKTGGGSQPQPAS-GQLQ 3730 G G+ A P+ PG + +G P P G G G + P G+ Sbjct: 779 KGEGGAPGLPGIAGPRGSPGERGE-TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837 Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKS---CTKGPREAGEQGPHGSLG-PKEKGESS 3786 P S P+ P P+ + + P G GP GS G P G S Sbjct: 838 PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG 897 Query: 3787 TKRKKGQVPGPARSESV-------GSFGRAPSAPDK-------PPRTPRKQA----TPSR 3828 + K G PGPA + G G A +K PP P T +R Sbjct: 898 SPGKDGP-PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956 Query: 3829 VLPTKP-KPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 L P P + P P + +PG G PQG P Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP 1001 Score = 47.8 bits (112), Expect = 2e-04 Identities = 193/831 (23%), Positives = 244/831 (29%), Gaps = 165/831 (19%) Query: 2321 PTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRT 2380 PT PP G GP P G G + DPG P S + P C S G + Sbjct: 95 PTRPPN--GQGPQGPKGDPGPPGIPGRNG-DPGIPGQPGSPGSPGPPGICESCPTG-PQN 150 Query: 2381 TAPSSTASDFQSDSPQSHRNASHQTPQGDP--LGPQDLKQR-----SRGYKKKPASTENG 2433 +P + D +S A + P G P GP S GY+ P E G Sbjct: 151 YSPQYDSYDVKSGVAVGGL-AGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG--EPG 207 Query: 2434 QWKGQAPHGPVTCEVCAASFRSGP-GLSRHKARKHRPH----PGAPAEPSPAALPAQQPL 2488 Q P GP A SGP G R RP PG P PA +P Sbjct: 208 QAGPSGPPGPP-----GAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF--- 259 Query: 2489 EPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPP 2548 P K HR G + N +G+ T P +G + G+P P Sbjct: 260 ---------PGMKGHR--GFDGRNGEKGE----TGAPGLKGENGLPGENGAPG-----PM 299 Query: 2549 SPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRG 2608 P P + RP P A R R P G + Sbjct: 300 GPRG------APGERGRPGL-------PGAAGARGNDGARGSDGQPGPPGPPGTAG---- 342 Query: 2609 KLRGRRLREESILPVSADVISDGRGSRPSPAMASYAAS--PSHCLSVEGGPEADGEQPPR 2666 G + + P + + G R P +A + P + G P GE P Sbjct: 343 -FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401 Query: 2667 LATLGPGVM-----------EGAAETDQEALCAGETGAQKPPGDR-----MLCPG----- 2705 PG+M GA A G+ GA+ PG R PG Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461 Query: 2706 ---RMDGAALGEQPTGQKGAS----ARGFWGPRETKAL----GVCKESGSE-PAEDSSRA 2753 DG+ G GA+ A GF GP + G E G+ PA A Sbjct: 462 GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAA 521 Query: 2754 HSRSEEGVWEENTPPLGP--LGFPETSSSPADSTTSSCLQGLPDNPDTQG-----GVQGP 2806 +GV P GP G P + P G P P +QG G GP Sbjct: 522 GEPGRDGV------PGGPGMRGMPGSPGGPGS-------DGKPGPPGSQGESGRPGPPGP 568 Query: 2807 EGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPS 2866 GP P + PGG + P P PT P Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG--PGPQGPPGKNGETGPQGPPGPTGPG 626 Query: 2867 FEEGGDPTLGPARLP----TDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPG 2922 ++G GP L T + P D G P G R P Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPP 686 Query: 2923 IDPWAPGLSLWALEPSREAGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSS 2982 APGL A P E G K + P P L +P GL P P D Sbjct: 687 GLAGAPGLRGGAGPPGPEGG--KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKG 744 Query: 2983 SSLGDVS------------------PEPPSLERERCDGGLPGNTHLLPLRATDFEVLSTK 3024 G + P P ++ +GG PG + R + E Sbjct: 745 EPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE----- 799 Query: 3025 FEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQSRRTEEAAGAGRAQG 3075 G PGP+ F G G + E A + +G Sbjct: 800 ------------RGETGPPGPA--GFPGAPGQNGEPGGKGERGAPGEKGEG 836 Score = 46.6 bits (109), Expect = 5e-04 Identities = 95/395 (24%), Positives = 131/395 (33%), Gaps = 74/395 (18%) Query: 3505 PVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQ 3564 P T P R P N Q P P P + GD + G +P + SPG PG + Sbjct: 91 PPTAPTR----PPNGQGPQGPKGDPGPPGIPGRNGDPGIPG---QPGSPGSPGPPG--IC 141 Query: 3565 QALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSS 3624 ++ P G P+ + D+ ++ + G PG G P Sbjct: 142 ESCPTG---PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPP---------------- 182 Query: 3625 SHMVSEGGPRGTF-HKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GE 3682 GP GT H GS P G Q + A P P G++ P G Sbjct: 183 -------GPPGTSGHPGSPGSP-GYQGPPGEPGQAG--------PSGPPGPPGAIGPSGP 226 Query: 3683 LARGTENGMKPATP--KAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAK- 3739 + E+G +P P + PGP + PG G + + ET K Sbjct: 227 AGKDGESG-RPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKG 285 Query: 3740 -PSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPA 3798 P + AP + R P E G G G+ G +G + GQ PGP Sbjct: 286 ENGLPGENGAPGPMGPRG-------APGERGRPGLPGAAG--ARGNDGARGSDGQ-PGPP 335 Query: 3799 RSESVGSFGRAPSAPDK--PPRTPRKQATPSRVLPTKPK--PNSQNKPRPPPSEQRKAEP 3854 F +P A + P +P P + P+ +Q P PP Sbjct: 336 GPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN------ 389 Query: 3855 GHTQRKDRLGKAFPQGRPLL---RPPKRGTAVHGA 3886 G K +G A G P L R P +GA Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424 Score = 38.1 bits (87), Expect = 0.17 Identities = 32/114 (28%), Positives = 40/114 (35%), Gaps = 12/114 (10%) Query: 3189 GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRAR 3248 GL G + + EP P+ RG+ AG PG P + + K SPGE P A Sbjct: 426 GLRGGAGEPGKNGAKGEPGPRGERGE------AGIPGVPGAKGEDGKDGSPGE---PGAN 476 Query: 3249 STPSNPDGAATP---DSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299 P P A + P R P P+ A GEP P Sbjct: 477 GLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530 Score = 38.1 bits (87), Expect = 0.17 Identities = 26/89 (29%), Positives = 31/89 (34%), Gaps = 9/89 (10%) Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264 EP K RG G PG G PG + R +P P A P + Sbjct: 820 EPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA-- 877 Query: 3265 ATALADAGSPGPPRTTPSPSPDPWAGGEP 3293 G PGPP + +P P P G P Sbjct: 878 ------RGLPGPPGSNGNPGP-PGPSGSP 899 Score = 37.7 bits (86), Expect = 0.23 Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 14/79 (17%) Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264 EP PK AG+PG P G +G+A +PGER P P GA P Sbjct: 658 EPGPKGD---------AGAPGAP-GGKGDA--GAPGERGPPGLAGAPGLRGGAGPPGPEG 705 Query: 3265 ATALADAGSPGPPRTTPSP 3283 AG PGPP +P Sbjct: 706 GKGA--AGPPGPPGAAGTP 722 Score = 37.4 bits (85), Expect = 0.30 Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 11/95 (11%) Query: 3206 PAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAKKDSPGERAKPRARSTPSNPDGAATP 3260 P P GK AG+ G P G +G+A + PGE+ P A+ P P Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQ--PGEKGSPGAQGPPGAPGPLGIA 950 Query: 3261 DSASATALADAGSPGPPRTTPSPSPDPWAG--GEP 3293 A L AG PG P SP P G G+P Sbjct: 951 GITGARGL--AGPPGMPGPRGSPGPQGVKGESGKP 983 Score = 35.8 bits (81), Expect = 0.86 Identities = 58/214 (27%), Positives = 66/214 (30%), Gaps = 32/214 (14%) Query: 3414 RGGRQPFAFRGVR-RPGAPGQKA-RALEGT--LPSKRRRVAMPGSAPGPGEDRPPPRGSS 3469 RG P +G +PGA G R G LP PG PG D P R S Sbjct: 968 RGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS 1027 Query: 3470 P----ILSEGSLPALLHLCSEVAPS-----TTKGWPETLERPVDPVTHPIRGCELPSNHQ 3520 P E P P K P P G P+ + Sbjct: 1028 PGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA-----GAPGPAGSR 1082 Query: 3521 ECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQAL-----------PL 3569 P P RG + G P N +PGSPGP QQ P+ Sbjct: 1083 GAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPV 1142 Query: 3570 GASLPRPGARGQDAEGKRAPLVFSGKRRAPGARG 3603 G S P PG G G P+ G R G RG Sbjct: 1143 GPSGP-PGKDG--TSGHPGPIGPPGPRGNRGERG 1173 Score = 35.8 bits (81), Expect = 0.86 Identities = 30/97 (30%), Positives = 35/97 (36%), Gaps = 17/97 (17%) Query: 3209 KHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAA---------- 3258 K HRG A GSPG P GQ+G P P S P DG + Sbjct: 1106 KGHRGFPGNPGAPGSPG-PAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPG 1164 Query: 3259 ----TPDSASATALADAGSPGPPRTTPSPSPDPWAGG 3291 + S + G PGPP P +P P GG Sbjct: 1165 PRGNRGERGSEGSPGHPGQPGPPG--PPGAPGPCCGG 1199 Score = 34.3 bits (77), Expect = 2.5 Identities = 29/84 (34%), Positives = 30/84 (35%), Gaps = 7/84 (8%) Query: 3213 GKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRA---RSTPSNPDGAATPDSASATALA 3269 G A AGS G P Q K GER R P NP +P A Sbjct: 1071 GPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGA- 1129 Query: 3270 DAGSPGP--PRTTPSPSPDPWAGG 3291 GSPGP PR PS P G Sbjct: 1130 -IGSPGPAGPRGPVGPSGPPGKDG 1152 Score = 33.9 bits (76), Expect = 3.3 Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 13/105 (12%) Query: 3189 GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRAR 3248 G +G+ L P K RG+ + A G+PG P G P ++ R Sbjct: 1011 GRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHP----GPPGPVGPAGKSGDRGE 1066 Query: 3249 STPSNPDGAATPDSASATALADAGSPGP--PRTTPSPSPDPWAGG 3291 S P+ P GA P G+PGP PR + + A G Sbjct: 1067 SGPAGPAGAPGP-------AGSRGAPGPQGPRGDKGETGERGAAG 1104 Score = 33.1 bits (74), Expect = 5.6 Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 10/103 (9%) Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGE-AKKDSPGERAKPRARSTPSNP--DGAATPD 3261 E P G AG PG P G +GE PG P AR P P +G P Sbjct: 835 EGGPPGVAGPPGGSGPAGPPG-PQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893 Query: 3262 SASATALADAGSPGPPRTTPSPSPDPWAG-----GEPLLQATP 3299 S + D G PGP T +P +G G+P + +P Sbjct: 894 GPSGSPGKD-GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSP 935 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 103 bits (256), Expect = 4e-21 Identities = 306/1259 (24%), Positives = 383/1259 (30%), Gaps = 230/1259 (18%) Query: 81 QAPSSTPGKRG--SPQTPPGRSPLQAPSRLAGR-AEGSPPQRYILGIASSRTKPTLDETP 137 + P G RG P PPGR + L G PP LG P L Sbjct: 111 EGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLG---GNFAPQLSYGY 167 Query: 138 ENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYT 197 + +P P GP G P PG P + FQ PP Sbjct: 168 DEKSTGGISVPGPMGPSGP-RGLPGPPGAPGPQG------------FQGPPG-------- 206 Query: 198 SPSATP-RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPE 256 P P A GP RG P PG + +G P P G+P Sbjct: 207 ----EPGEPGASGPMGPRG-PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261 Query: 257 PIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEE 316 P KG R F L GA PA G + G GA Sbjct: 262 PGMKGHR------------GFSGLDGAKGDAGPAGPKGEPGSPG--------ENGA---- 297 Query: 317 AVGTGPAYPLPTQPAPSPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAPRPFSDS 371 P Q P LP +G+PG G + +GA PG A P Sbjct: 298 ----------PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG 347 Query: 372 LHKSLTKILPERPPSAQ--DGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAA 429 + + P+ P ++ G+ GPP P A +G + G P + A Sbjct: 348 AVGAKGEAGPQGPRGSEGPQGVRGEPGPPG-------PAGAAGPAGNPGADGQPGAKGAN 400 Query: 430 PGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489 P A P P PGGP + +G+P AP Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN---SGEP----------GAPGSKGDTGA 447 Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFT 549 P P G++ GP G +G G G+ PGP LP +GG Sbjct: 448 KGEPGPVGVQ----------GPPGPAGEEGKRGARGE-PGP-TGLPGPPGERGGP----- 490 Query: 550 YNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA--TNTAGSTCSS 607 PGA GVA P+ P G P P SP E+ P A G T S Sbjct: 491 -GSRGFPGAD----GVAGPK-GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP 544 Query: 608 LSP---MSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSP-----EPPHSLPT 659 SP + P P+ ++ + PGP GP P Q FP P EP + Sbjct: 545 GSPGPDGKTGPPGPAGQDGR-PGPPGP-----PGARGQAGVMGFPGPKGAAGEPGKAGER 598 Query: 660 HYQPEPAKAFPFPADG-LGAEGAFQCLEETPFPHEGPEVGRGGLQGFP-RAPPPYPTHHF 717 P P DG GA+G E G G QG P A PP Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658 Query: 718 SLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPP 777 D L G R G + GPPG P Sbjct: 659 GEQGVPGD---------------------LGAPGPSGARGERGFPGERGVQGPPGPAGPR 697 Query: 778 AAPRVPADAHAGLLSHAKTFLLAGDAQAEG----KDDPLRTGFLPSLAATPFPLPASDL- 832 A P + A GDA A G + P G A P P D Sbjct: 698 GANGAPGNDGA-----------KGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG 746 Query: 833 DMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT 892 D S + + G+ P + D + PSGP GP+ G Sbjct: 747 DAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK-GESGPSGPAGPTGARGAPGDRG-- 803 Query: 893 PESKAPPPLPAATPDPQTPRPGDRGCP-ARGRPKTRSLGLAPTEADAPSQGRQQRRGKQL 951 + PP PA P PG G P A+G P G A + DA G G Sbjct: 804 ---EPGPPGPAGFAGP----PGADGQPGAKGEP-----GDAGAKGDAGPPGPAGPAGPPG 851 Query: 952 KLFRKDLDSGGAAEGSGSGGGGRASGL--------RPRRNDGLGERPPPRPR-RPRTQAP 1002 + ++ + GA GS G A+G P + G PP P + + P Sbjct: 852 PI--GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGP 909 Query: 1003 GSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLR 1062 PA R P P + + P P G G +V + Sbjct: 910 RGETGPAGR-PGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968 Query: 1063 EYDFASESEEDEQPPPRGP-GFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGD 1121 E F +P +GP G G RG L GP + ++ A G D Sbjct: 969 ERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA-GPPGESGREGAPGAEGSPGRD 1027 Query: 1122 GAPANPEEPGGSRP-GPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTN 1180 G+P + G + P GP +P A P G A + G DR P P P Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGA--PGAPGPVGPAGKSG-----DRGETGPAGPAG-PVG 1079 Query: 1181 TETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQP 1240 P A+ P + D E E G G S GL P P Sbjct: 1080 -------------PVGARGPAGPQGPRGDKGETGE---QGDRGIKGHRGFS-GLQGPPGP 1122 Query: 1241 PPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297 P S + G SG P GS+ PG L G GP G P P PG Sbjct: 1123 PGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPG 1181 Score = 96.3 bits (238), Expect = 5e-19 Identities = 229/866 (26%), Positives = 272/866 (31%), Gaps = 170/866 (19%) Query: 6 PRGAPPPT-MTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQ 64 PRG+ P + G+ P A + G P+ P D P KGA A G A A P A+ Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGAAG-PAGNPGADGQPGA---KGANGAPGIAGAPGFPGAR 415 Query: 65 PRQARDGELKPPSLRGQAPS-STPGKRGSP--QTPPGRSPLQAPSRLAGR-----AEGSP 116 G PP +G + PG +G + PG +Q P AG A G P Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475 Query: 117 PQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDT----PQGPGTGAPLRPGLPRTEAQ 172 + G R P P + + P + P GP G+P G P Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGP-KGSPGEAGRPGEAGL 534 Query: 173 PAAEELGFHRCFQEPPSSFTSTNYTSPSATP----RPPAPGPPQSRGTSPLQPGSYPEYQ 228 P A+ L P S T P RP PGPP +RG + + P+ Sbjct: 535 PGAKGL------TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPK-- 586 Query: 229 ASGADSWP-PAAENSFPGANFGVPPA----------EPEPI-PKGSR----PGGSPRGVS 272 GA P A E PG V PA P P P G R P GSP Sbjct: 587 --GAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP---G 641 Query: 273 FQ-FPFPA-LHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPL---- 326 FQ P PA G + KP V G GP + + + +P E GP P Sbjct: 642 FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGP---SGARGERGFPGERGVQGPPGPAGPRG 698 Query: 327 ----------------PTQPAPSPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAP 365 P P P QG PG GL G GA S Sbjct: 699 ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS-- 756 Query: 366 RPFSDSLHKSLTKILPERP-----------PSAQDGLGSTRGPPSSLPQRHFPGQAYRAS 414 P D + I P P PS G RG P + PG A A Sbjct: 757 -PGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815 Query: 415 --GVDTSPG----PPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQP 468 G D PG P D PP P P P G + A + G Sbjct: 816 PPGADGQPGAKGEPGDAGAKGDAGPPG-------PAGPAGPPGPIGNVGAPGAKGARGSA 868 Query: 469 SPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP 528 P P +A P P P G P PAG E G +G G AG+ Sbjct: 869 GPPGATGFPGAAGRVGP-------PGPSGNAGPPGPPGPAG-KEGGKGPRGETGPAGRPG 920 Query: 529 GPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQ--VSPHGTPSLPPPRVVGA 586 P + + GSP G P P G PQ G LP R Sbjct: 921 EVGPPGPPGPAGEKGSP------GADGPAGAP---GTPGPQGIAGQRGVVGLPGQRGERG 971 Query: 587 SPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGS 646 P LP P S P P+ S E PGP+GP PP G+ Sbjct: 972 FPG---LPGP----------SGEPGKQGPSGASGERGP-PGPMGPPGLAGPPGESGREGA 1017 Query: 647 PFPSPEPPHSLPTHYQPEPAKAFPF-PADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGF 705 P P + + + P P GA GA P G RG Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA-----PGPVGPAGKSGDRGETGPA 1072 Query: 706 PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQ 765 A P P + + D T Q DR HR F GL Q Sbjct: 1073 GPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIK------GHRGFSGL---------Q 1117 Query: 766 RSPGPPGLP--------SPPAAPRVP 783 PGPPG P S PA PR P Sbjct: 1118 GPPGPPGSPGEQGPSGASGPAGPRGP 1143 Score = 90.5 bits (223), Expect = 3e-17 Identities = 322/1378 (23%), Positives = 400/1378 (29%), Gaps = 312/1378 (22%) Query: 131 PTLDETPENPQLEAAQLPEVDT----PQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQE 186 P E+P + + + P+ DT P+GP G P R G+P P Sbjct: 96 PDGSESPTDQETTGVEGPKGDTGPRGPRGPA-GPPGRDGIPGQPGLPG------------ 142 Query: 187 PPSSFTSTNYTSPSATPRPPAPGPPQSRGT-SPLQPGSYPEYQASGADSWPPAAENSFPG 245 P P PP GPP G +P Y E G S PG Sbjct: 143 ------------PPGPPGPP--GPPGLGGNFAPQLSYGYDEKSTGGI---------SVPG 179 Query: 246 ANFGVPPAEPEPIPKGSRPGGSPRGVSFQFP--FPALHGASTKPFPADVAGHAFTNGPLV 303 + P+ P +P P G+P FQ P P GAS P G NG Sbjct: 180 P---MGPSGPRGLPG---PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGD-- 231 Query: 304 FAFHQPQGAWPEEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAA 361 + P GP P + P + LP +G G S L GA G A Sbjct: 232 ----DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRG----FSGLDGAKGDAGPA 283 Query: 362 HSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPG 421 P + G G P + R PG+ R +PG Sbjct: 284 G----------------------PKGEPGSPGENGAPGQMGPRGLPGERGRPG----APG 317 Query: 422 PP-----DTELAAPGPP----PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQ 472 P D A GPP PA P A P GP + G+P P Sbjct: 318 PAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-- 375 Query: 473 RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--GSQGALGTAGKTPGP 530 P A P P A P G + + P AG P + G G G G G PGP Sbjct: 376 ----PGPAGAAGPAGNPGADGQP-GAKGANGAPGIAGAPGFPGARGPSGPQGPGGP-PGP 429 Query: 531 REKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSE 590 + G P G T +P GV P G R P Sbjct: 430 K--------GNSGEPGAPGSKGDTGAKGEPGPVGVQ----GPPGPAGEEGKRGARGEPGP 477 Query: 591 SPLPSPATNTAGSTCSSLSPMS--SSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPF 648 + LP P G + P P+ E PGP GP P E G P Sbjct: 478 TGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS-PGPAGPKGSPGEAGRPGEAGLP- 535 Query: 649 PSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRA 708 AK G +G +T P + GR G G P A Sbjct: 536 ----------------GAKGLTGSPGSPGPDG------KTGPPGPAGQDGRPGPPGPPGA 573 Query: 709 PPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSP 768 R + + F + G K G + P Sbjct: 574 -----------------------------RGQAGVMGFPGPKGAAG---EPGKAGERGVP 601 Query: 769 GPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLP 828 GPPG P D AG AG A G+ P + L P Sbjct: 602 GPPGAVGPAGK-----DGEAGAQGPPGP---AGPAGERGEQGPAGSPGFQGLPGPAGPPG 653 Query: 829 ASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSK 888 + E D L +G + P + P GP GP + Sbjct: 654 EAGKPGEQGVPGD-LGAPGPSGARGERGFPGERGV-------QGPPGPAGPRGANGAPGN 705 Query: 889 AGVTPESKAP-PPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRR 947 G ++ AP P P Q PG+RG PK P AD S G+ R Sbjct: 706 DGAKGDAGAPGAPGSQGAPGLQG-MPGERGAAGLPGPKGDRGDAGPKGADG-SPGKDGVR 763 Query: 948 GKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRAD 1007 G + G A G G SG P P R APG R + Sbjct: 764 G-----LTGPIGPPGPAGAPGDKGESGPSG-------------PAGPTGARG-APGDRGE 804 Query: 1008 PAPRVPRAAALPEETRSSRRRRLPPRK-DPRKRKARGGAWGKELILKIVQQKNRLREYDF 1066 P P P A P P K +P A+G A Sbjct: 805 PGPPGPAGFAGPPGADGQ-----PGAKGEPGDAGAKGDAGPP------------------ 841 Query: 1067 ASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDG 1122 + P P G PG +G RG P P AG G Sbjct: 842 -GPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG----NAGPPG 896 Query: 1123 APANPEEPGGSRP----GPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVP 1178 P + GG P GP P GP G A +G P AD P+ AP P Sbjct: 897 PPGPAGKEGGKGPRGETGPAGRPGEVGPPGP--PGPAGEKGSPG-ADGPAGAPGTP---- 949 Query: 1179 TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPE 1238 + R + P + E P E + P+ +GE G PG + P Sbjct: 950 -GPQGIAGQRGVVGLPGQRGERGFPGLPGPSG----EPGKQGPSGASGERGP-PGPMGPP 1003 Query: 1239 Q---PPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQ 1295 PP G P GS G+ G G PG AP + Sbjct: 1004 GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA---------- 1053 Query: 1296 PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL 1355 PG + P P+ PAG P+G PV +GP P + Sbjct: 1054 PGP-VGPAGKSGDRGETGPA-----------GPAG----PVG-PVGARGPAGPQGPRGD- 1095 Query: 1356 FLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGR 1415 G G + H S PP + G +G+ P PR PPG+A PG+ Sbjct: 1096 -KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQG-PSGASGPAGPRGPPGSAGA-PGK 1152 Query: 1416 AASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSF 1473 LP PP G D+G P PP P PP F Sbjct: 1153 DG----------LNGLP-GPIGPP--GPRGRTGDAG-PVGPPGPPGPPGPPGPPSAGF 1196 Score = 83.2 bits (204), Expect = 5e-15 Identities = 212/802 (26%), Positives = 259/802 (32%), Gaps = 166/802 (20%) Query: 27 PGHPSQPPLEDN-TPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRG----Q 81 PG P P L N P + GG + + + PR G PP G Q Sbjct: 147 PGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPR----GLPGPPGAPGPQGFQ 202 Query: 82 APSSTPGKRGS--------PQTPPGRSPLQAPSRLAGR-----------AEGSPPQRYIL 122 P PG+ G+ P PPG++ + GR A G P + Sbjct: 203 GPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLP 262 Query: 123 GIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPG-TGAP--LRP-GLPRTEAQPAAEEL 178 G+ R LD + +A P PG GAP + P GLP +P A Sbjct: 263 GMKGHRGFSGLD----GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318 Query: 179 GFHRCFQEPPSSFTSTNYTSPSATPRPPA-------------------------PGPPQS 213 R + T P+ P P PGPP Sbjct: 319 AGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378 Query: 214 RGTS--PLQPGSYPEYQASGADSWPP-AAENSFPGANFGVPPAEP--EPIPKGS--RPG- 265 G + PG+ + A GA+ P A FPGA P P P PKG+ PG Sbjct: 379 AGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGA 438 Query: 266 ----------GSPRGVSFQF-PFPA----LHGASTKPFPADVAG-HAFTNGPLVFAFHQP 309 G P V Q P PA GA +P P + G GP F Sbjct: 439 PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA 498 Query: 310 QGAWPEEAVGTGPAYPLPTQPAPSPL-----PCYQGQPG--GLNRHSDLSGALSSPGAAH 362 G GP P + +P P P G+PG GL L+G+ SPG Sbjct: 499 DGV-------AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDG 551 Query: 363 SAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQ---RHFPGQAYRASGVDTS 419 P P+ QDG GPP + Q FPG G Sbjct: 552 KTGPP----------------GPAGQDGRPGPPGPPGARGQAGVMGFPG----PKGAAGE 591 Query: 420 PGPPDTELAAPGPPPARLPQLWDPTA-APYPTPPGGPL------AATRSMFFNGQPSPGQ 472 PG E PGPP A P D A A P P GP S F G P P Sbjct: 592 PGKAG-ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAG 650 Query: 473 RLCLPQSAPLPWPQVLP--TARPSPHGMEMLSRLPFPAG--GPEWQGGSQGALGTAGKTP 528 P A P Q +P P P G P G GP G +GA G G Sbjct: 651 P---PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDG 707 Query: 529 GPREK-LPAVRSSQG-----GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPR 582 + P SQG G P G+ P G A P+ G+P R Sbjct: 708 AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDR---GDAGPK-GADGSPGKDGVR 763 Query: 583 VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPP---T 639 + P P P+ A G + S P + A + + PGP GP+ F PP Sbjct: 764 GL-TGPIGPPGPAGAPGDKGESGPS-GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG 821 Query: 640 HPQETGSPFPSPEPPHSLPTHYQPEPA--KAFPFPADGLGAEGAFQCLEE------TPFP 691 P G P + + P P PA P P +GA GA T FP Sbjct: 822 QPGAKGEPGDAGAKGDAGP----PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFP 877 Query: 692 HEGPEVGRGGLQGFPRAPPPYP 713 VG G G A PP P Sbjct: 878 GAAGRVGPPGPSG--NAGPPGP 897 Score = 79.7 bits (195), Expect = 5e-14 Identities = 196/772 (25%), Positives = 235/772 (30%), Gaps = 156/772 (20%) Query: 6 PRGAP-PPTMTGDLQPRQVASSPG--HPSQPPLEDNTPATRTTKGAREAGGQAQAMELPE 62 P G P PP G R + G P P E +P KG+ G+ LP Sbjct: 477 PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPG 536 Query: 63 AQPRQAR------DGELKPPSLRGQ----APSSTPGKRGSPQT---PPGRSPLQAPSRLA 109 A+ DG+ PP GQ P PG RG P + P + Sbjct: 537 AKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596 Query: 110 GRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPG-TGAPLRPGLPR 168 R PP +G A + + P P A + E PG G P G P Sbjct: 597 ERGVPGPPGA--VGPAGKDGEAGA-QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228 +P + + P + + PP P P+ +P G+ + Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713 Query: 229 ASGADSWPPAAENSFPGANFGVPP---AEPEPIPKGSRPGGSPRGVSF---QFPFPALHG 282 A GA P ++ + PG G+P A P PKG R P+G + L G Sbjct: 714 APGA----PGSQGA-PGLQ-GMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTG 767 Query: 283 ASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPL---PCYQ 339 P PA G +GP P G P A G P P P+ P Sbjct: 768 PIGPPGPAGAPGDKGESGP-----SGPAG--PTGARGAPGDRGEPGPPGPAGFAGPPGAD 820 Query: 340 GQPGGLNRHSDLS--GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGP 397 GQPG D G PG A A P I P A+ GS GP Sbjct: 821 GQPGAKGEPGDAGAKGDAGPPGPAGPAGPP---------GPIGNVGAPGAKGARGSA-GP 870 Query: 398 PSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP-PARLPQLWDPTAAPYPT------ 450 P + FPG A R P P PGPP PA P P Sbjct: 871 PGATG---FPGAAGRVG-----PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV 922 Query: 451 -PPGGPLAATRSMFFNGQPSPGQRLCLPQSAP-LPWPQVLPTAR-----PSPHGMEMLSR 503 PPG P A G P P AP P PQ + R P G Sbjct: 923 GPPGPPGPAGEK----GSPGADG----PAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974 Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGP--------------REKLPAVRSSQG--GSPAL 547 LP P+G P QG S GA G G PGP RE P S G GSP Sbjct: 975 LPGPSGEPGKQGPS-GASGERGP-PGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGA 1032 Query: 548 FTYNGMTDPGAQPLFFGV--AQPQVSPHG-------TPSLPPPRVVGASPSESPL-PSPA 597 G T P P G A V P G T P VG + P P Sbjct: 1033 KGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGP 1092 Query: 598 TNTAGSTCSS----------LSPMSSSPANPSSEESQ----------------------- 624 G T S + P P S Q Sbjct: 1093 RGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGK 1152 Query: 625 -----LPGPLGP------SAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEP 665 LPGP+GP + P P G P P P + P+P Sbjct: 1153 DGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQP 1204 Score = 76.6 bits (187), Expect = 4e-13 Identities = 270/1079 (25%), Positives = 337/1079 (31%), Gaps = 211/1079 (19%) Query: 1881 GPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLP 1940 GP +DGI G L P P GL G +++ G + S GG+ V Sbjct: 124 GPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAP--QLSYGYDEKSTGGISVPGPM 181 Query: 1941 AVAGHQLGLE----ADGHWGLLGQAEKTQGQGTANQLQPENGVSP---GGTDNHASVNAS 1993 +G + GL A G G G + G + + P P G D A Sbjct: 182 GPSGPR-GLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGR 240 Query: 1994 P-KTALTGPT-----EGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHS 2047 P + GP G L KG R L + A+ P P E + A Sbjct: 241 PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGL-DGAKGDAGPAGPKGEPGSPGENGAPG 299 Query: 2048 RSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDP 2107 + G G ER PG P A G+ A AA P PT A P G + + Sbjct: 300 QMGPRGLPGERGR-PGAPGPAGARGNDGATG----AAGPPGPTGPAGPPGFPGAVGAKGE 354 Query: 2108 LTSPSRAQGGLGGQ-LPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPV 2166 P +G G Q + P PPGP A PA P ADG GA+ + Sbjct: 355 -AGPQGPRGSEGPQGVRGEPG---PPGPAG--AAGPAGNP--GADG-----QPGAKGANG 401 Query: 2167 APPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPE 2226 AP + +P P +G P + P PPG PK ++ Sbjct: 402 AP-GIAGAPGFPGA-------RGPSGP-QGPGG-PPG-------------PKGNS----- 433 Query: 2227 DSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGR-------GLPGPD 2279 PG S GA V G P G+E + G GLPGP Sbjct: 434 --------GEPGAPGSKGDTGAKGEPGPVGVQGPPG-PAGEEGKRGARGEPGPTGLPGP- 483 Query: 2280 PQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGA-GPDSPACL 2338 P RG P RG G A P P +G+ GP P Sbjct: 484 PGERGGPGS-------RGFP--------------GADGVAGPKGPAGERGSPGPAGPKGS 522 Query: 2339 EGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSH 2398 GE G P + G P G G T P P G+T P D + P Sbjct: 523 PGEAG----RPGEAGLP--GAKGLTGSPGSPGPD-----GKTGPPGPAGQDGRPGPPGPP 571 Query: 2399 RNASHQTPQGDPLGPQDL-----KQRSRGYKKKPAST----ENGQWKGQAPHGPVTCEVC 2449 G P GP+ K RG P + ++G+ Q P GP Sbjct: 572 GARGQAGVMGFP-GPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG---- 626 Query: 2450 AASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHR----- 2504 A R G + + P P P P A P +Q + P + R Sbjct: 627 PAGERGEQGPAGSPGFQGLPGPAGP--PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE 684 Query: 2505 --VSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPAS 2562 V G P RG P G+K APG+P SQ E + A Sbjct: 685 RGVQGPPGPAGPRG----ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGE---RGAAG 737 Query: 2563 KPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILP 2622 P P R D PK A+ G+ R T P G + K G P Sbjct: 738 LPGPKGDRGDA-GPKGADGSPGKDGVRGLT--GPIGPPGPAGAPGDK--GESGPSGPAGP 792 Query: 2623 VSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQ----------PPRLATLGP 2672 A RG P A +A P +G P A GE PP A GP Sbjct: 793 TGARGAPGDRGEPGPPGPAGFAGPPG----ADGQPGAKGEPGDAGAKGDAGPPGPA--GP 846 Query: 2673 GVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKG-ASARGFWGPR 2731 G G G+ PPG GAA P G G A G GP Sbjct: 847 AGPPGPIGNVGAPGAKGARGSAGPPGAT-----GFPGAAGRVGPPGPSGNAGPPGPPGPA 901 Query: 2732 ETKALGVCKESGSEPAEDSSRAHSRSEEG-------VWEENTPPL-GPLGFPETSSSPAD 2783 KE G P ++ A E G E+ +P GP G P T P Sbjct: 902 G-------KEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPG-PQG 953 Query: 2784 STTSSCLQGLPDN-----------PDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFS 2832 + GLP P + G QGP G + + PP L Sbjct: 954 IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESG 1013 Query: 2833 QLFPPG--GRLTRKRNPHVYGKRCE-----------KPVLPLPTQPSFEEGGDPTLGPA 2878 + PG G R +P G R E P P P P+ + G GPA Sbjct: 1014 REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA 1072 Score = 73.9 bits (180), Expect = 3e-12 Identities = 129/491 (26%), Positives = 161/491 (32%), Gaps = 75/491 (15%) Query: 3415 GGRQPFAFRGVRRP----GAPGQKARALEGTLPSKRRRVAMPGSA--------PGP-GED 3461 G + P RG P G+PG+ R E LP + PGS PGP G+D Sbjct: 503 GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD 562 Query: 3462 -RPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWP-ETLER--PVDPVTHPIRGCELPS 3517 RP P G + + P G P + ER P P G + + Sbjct: 563 GRPGPPGPPGARGQAGVMGF------PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEA 616 Query: 3518 NHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP- 3576 Q P P+ PA +G G P PG G +Q +P P P Sbjct: 617 GAQGPPGPA---GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPS 673 Query: 3577 GARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGT 3636 GARG+ F G+R G G P + G P Sbjct: 674 GARGERG--------FPGERGVQGPPGPAGPRG-------------------ANGAPGND 706 Query: 3637 FHKGSATKPA--------GCQSSSKDRSAASTPS-KALKFPVHPRKAVGSLAPG-ELARG 3686 KG A P G Q +R AA P K + P+ A GS PG + RG Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS--PGKDGVRG 764 Query: 3687 TENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRS 3746 + P P PG + SG P TG P G+ A P Sbjct: 765 LTGPIGPPGPAGAPGDKGE-SGPSGPAGPTGARGAPGDR-GEPGPPGPAGFAGPPGADGQ 822 Query: 3747 PAPERLPARAQAKSCTKGPREAGEQGPHGSLG----PKEKGESSTKRKKGQVPGPARSES 3802 P + P A AK P AG GP G +G P KG + G P + Sbjct: 823 PGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882 Query: 3803 VGSFGRAPSA-PDKPPRTPRKQATPSRVLPTKP--KPNSQNKPRPPPSEQRKAEPGHTQR 3859 VG G + +A P PP K+ T P +P P PP K PG Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGP 942 Query: 3860 KDRLGKAFPQG 3870 G PQG Sbjct: 943 AGAPGTPGPQG 953 Score = 70.5 bits (171), Expect = 3e-11 Identities = 236/1034 (22%), Positives = 309/1034 (29%), Gaps = 161/1034 (15%) Query: 1879 LPGPGVAKSKDGILGL--QELTPAAQSP--PR--VNPSGLEGGTVEGGKVACGPAQGSPG 1932 LPGP A G G + P A P PR P G G E GK +G PG Sbjct: 189 LPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG 248 Query: 1933 -----GVQVTT-LPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSP----- 1981 G+ T LP + GH+ DG G G A G+ + + P Sbjct: 249 PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308 Query: 1982 -----------GGTDNHASVNASPKTALTGP-----------TEGAVLLEKCKGSRAAMS 2019 G N + A+ TGP +G + +GS Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG 368 Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGR--TPERASSPGL-----NKPLLATG 2072 ++ E P PP P + A + G++G P A +PG G Sbjct: 369 VRGE----PGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424 Query: 2073 DSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQ-LPASPSCRDP 2131 P P AP GP+ + P P+ +G G + P P Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGP-PGPAGEEGKRGARGEPGPTGLPGP 483 Query: 2132 PGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCD---PKEA-LAGC-- 2185 PG + P ADGV E P SP + P EA L G Sbjct: 484 PGERG----GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539 Query: 2186 LLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTP----KDSTLRIPEDSRKEKLWESPGRAT 2241 L GSP D + PPG P + + P G Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG 599 Query: 2242 SPPLAGAVSPSVAVRATGLSST--PTGDEAQAGRGLPGPDPQSRGAP-PHTNPDRMPRGH 2298 P GAV P+ G P G + G P P +G P P P + Sbjct: 600 VPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG 659 Query: 2299 SSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPE--DPGTPE 2356 P + G + P E GP P G G + + PG P Sbjct: 660 EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP- 718 Query: 2357 TGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQT----PQGDPLG 2412 G GA + + GL A +D T P G Sbjct: 719 -GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA 777 Query: 2413 PQDLKQRSRGYKKKPASTEN--GQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRP- 2469 P D + P G P GP A F PG K P Sbjct: 778 PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP-------AGFAGPPGADGQPGAKGEPG 830 Query: 2470 ---HPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPP 2526 G P PA PA P P+ P K + +G G V P P Sbjct: 831 DAGAKGDAGPPGPAG-PAGPP-GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP 888 Query: 2527 AQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRR 2586 + + G P PP P E K P + P R E+ P G Sbjct: 889 SGNA-------GPP-----GPPGPAGKE-GGKGPRGETGP-AGRPGEVGPPGPPGPAGE- 933 Query: 2587 WRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAAS 2646 + P D P+ + G + + G+R + RG R P + + Sbjct: 934 -KGSPGADGPAGAPGTPGPQ--GIAGQR---------GVVGLPGQRGERGFPGLPGPSGE 981 Query: 2647 PSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGR 2706 P +G A GE+ P PG+ E+ +E G GA+ PG + Sbjct: 982 PGK----QGPSGASGERGPPGPMGPPGLAGPPGESGRE----GAPGAEGSPGRDGSPGAK 1033 Query: 2707 MDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSE-------PAEDSSRAHSRSE 2758 D G P G GA A G GP +G +SG PA +R Sbjct: 1034 GDRGETG--PAGPPGAPGAPGAPGP-----VGPAGKSGDRGETGPAGPAGPVGPVGARGP 1086 Query: 2759 EGVWEENTPPLGPLGFPETSSSPADSTTS-----SCLQGLPDNPDTQG-----GVQGPEG 2808 G P GP G + D S LQG P P + G G GP G Sbjct: 1087 AG-------PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAG 1139 Query: 2809 P--TPDASGSSAKD 2820 P P ++G+ KD Sbjct: 1140 PRGPPGSAGAPGKD 1153 Score = 67.8 bits (164), Expect = 2e-10 Identities = 108/429 (25%), Positives = 138/429 (32%), Gaps = 52/429 (12%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPP----PRGSSPILSEGSLPALLHL 3483 PG PG A + PG A G+ PP P G + P Sbjct: 805 PGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGA 864 Query: 3484 CSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCAL 3543 P G+P R P PS + P P P PA G+G Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPG---------PSGNAGPPGP---PGPAGKEGGKGPRGE 912 Query: 3544 DGALERPENEASPGSPGPLLQQALPLGASLP--RPGARG-QDAEGKRAPLVFSGKRRAPG 3600 G RP PG PGP ++ P GA P PG G Q G+R + G+R G Sbjct: 913 TGPAGRPGEVGPPGPPGPAGEKGSP-GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERG 971 Query: 3601 ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAST 3660 G P + + S E GP G P G A + Sbjct: 972 FPGLPGPS--------GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023 Query: 3661 PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPG-PSSQGSGSPRPGTKTGGG 3719 P + +PG A+G PA P PG P + G P + G Sbjct: 1024 PGR-------------DGSPG--AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGE 1068 Query: 3720 SQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPRE-AGEQGPHGSLG 3778 + P +G + A PA P + P ++ Q KG R +G QGP G G Sbjct: 1069 TGPAGPAGPVGPVGARGPAGP----QGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124 Query: 3779 -PKEKGESSTKRKKGQVPGPARSESVGSFG-RAPSAPDKPPRTPRKQATPSRVLPTKPKP 3836 P E+G S G P + + G G P PP + V P P P Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGP-P 1183 Query: 3837 NSQNKPRPP 3845 P PP Sbjct: 1184 GPPGPPGPP 1192 Score = 67.4 bits (163), Expect = 3e-10 Identities = 169/642 (26%), Positives = 207/642 (32%), Gaps = 104/642 (16%) Query: 3 GER----PRGAPP-PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQA 57 GER P G+P + G P A PG P + P +G R G+ Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG-DLGAPGPSGARGERGFPGERGV 687 Query: 58 MELPEAQPRQARDGELKPPSLRGQAPS-STPGKRGSP--QTPPG-RSPLQAPSRLAGR-- 111 P + +G +G A + PG +G+P Q PG R P R Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD 747 Query: 112 -----AEGSPPQRYILGIASSRTKPTL-----DETPENPQLEAAQLPEVDTPQGPGTGAP 161 A+GSP + + G+ P D+ P A P G P Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGP 807 Query: 162 LRP----GLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTS 217 P G P + QP A+ EP + + P P PA GPP Sbjct: 808 PGPAGFAGPPGADGQPGAKG--------EPGDAGAKGDAGPPG--PAGPA-GPP-----G 851 Query: 218 PLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPE--------PIPKGSRPGGSPR 269 P+ P + + + PP A FPGA V P P P P G G PR Sbjct: 852 PIGNVGAPGAKGARGSAGPPGA-TGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPR 910 Query: 270 GVSFQFPFPALHGASTKPFPADVAGHAFTNGPL-VFAFHQPQGAWPEEAV----GTGPAY 324 G + P G P PA G +GP PQG + V G Sbjct: 911 GETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGER 970 Query: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384 P P PS P QG P G + G + PG A P +S E Sbjct: 971 GFPGLPGPSGEPGKQG-PSGASGERGPPGPMGPPGLA----GPPGESGR--------EGA 1017 Query: 385 PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP-PPARLPQLWDP 443 P A+ G G P + R G A G +PG P APGP PA Sbjct: 1018 PGAEGSPGRD-GSPGAKGDRGETGPA----GPPGAPGAP----GAPGPVGPAGKSGDRGE 1068 Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503 T P P GP+ A G P P+ + G L Sbjct: 1069 TGPAGPAGPVGPVGA------RGPAGPQG----PRGDKGETGEQGDRGIKGHRGFSGLQG 1118 Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQP--- 560 P P G P QG S GA G AG P G+P NG+ P P Sbjct: 1119 PPGPPGSPGEQGPS-GASGPAGPRGPP---------GSAGAPGKDGLNGLPGPIGPPGPR 1168 Query: 561 LFFGVAQPQVSPHGTPSLP-PPRVVGASPSESPLPSPATNTA 601 G A P V P G P P PP A S LP P A Sbjct: 1169 GRTGDAGP-VGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKA 1209 Score = 67.0 bits (162), Expect = 3e-10 Identities = 235/978 (24%), Positives = 311/978 (31%), Gaps = 195/978 (19%) Query: 1656 PFSPRGANFHFQPVQKAGASK--TGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAK- 1712 P P G +F P G + TG G P LP P PGPQ G + Sbjct: 149 PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP 208 Query: 1713 ----CSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPE-----PGTADQP----H 1759 S P + + E P E RG P+ PGTA P H Sbjct: 209 GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE-RGPPGPQGARGLPGTAGLPGMKGH 267 Query: 1760 RG--------------APAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQG 1805 RG P E GSP + AP G P + P P+ A Sbjct: 268 RGFSGLDGAKGDAGPAGPKGEP-GSPGENGAP--GQMGPRGLPGERGRPGAPGPAGARGN 324 Query: 1806 HSAGRAGGHLHPT--AGRPGFEG-----NEFAPAGASSLTAPRGREAWLVPVPSPACVSN 1858 A A G PT AG PGF G E P G P+G P P PA + Sbjct: 325 DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAG 383 Query: 1859 THPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRV----NPSGLEG 1914 PA +P PG A GI G P A+ P P G +G Sbjct: 384 ---------PAGNPGAD--GQPGAKGANGAPGIAGAPGF-PGARGPSGPQGPGGPPGPKG 431 Query: 1915 GTVE----GGKVACGPAQGSPGGVQVTTLPAVAGHQ--LGLEAD-GHWGLLGQAEKTQGQ 1967 + E G K G A+G PG V V P AG + G + G GL G + G Sbjct: 432 NSGEPGAPGSKGDTG-AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP 490 Query: 1968 GTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPT 2027 G+ + P G A SP A + G E + A + + + Sbjct: 491 GSRGFPGADGVAGPKGP---AGERGSPGPAGPKGSPG----EAGRPGEAGLPGAKGLTGS 543 Query: 2028 PSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAP 2087 P P P+ + T +G +GR PG P A G + P Sbjct: 544 PGSPGPDGK------TGPPGPAGQDGR-------PGPPGPPGARGQAGVMGF-------P 583 Query: 2088 SPTSAAHMPCSLGP--LPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWA 2145 P AA P G +P P+ G G Q P P+ +Q A SP + Sbjct: 584 GPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643 Query: 2146 PLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCL-------LQGE-GSPLEDP 2197 L P PP P ++ + G L +GE G P E Sbjct: 644 GL---------------PGPAGPPGEAGKP--GEQGVPGDLGAPGPSGARGERGFPGERG 686 Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257 PPG P+ + +PG + AGA + A Sbjct: 687 VQGPPGPAG----------PRGAN-------------GAPGNDGAKGDAGAPGAPGSQGA 723 Query: 2258 TGLSSTPTGDEAQAGRGLPGP-----DPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHR 2312 GL P G+ A GLPGP D +GA D + P A Sbjct: 724 PGLQGMP-GERGAA--GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD 780 Query: 2313 EGQAVTAVPTEPPTLQGA-------GPDSPACLEGEMGTSSKEPEDPGTP-ETGRSGATK 2364 +G++ + P P +GA GP PA G G +P G P + G G Sbjct: 781 KGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG-QPGAKGEPGDAGAKGDAG 839 Query: 2365 MPRVTCPSTGLG-LGRTTAP------SSTASDFQSDSPQSHRNASHQTPQGD--PLGPQD 2415 P P+ G +G AP S + P + P G+ P GP Sbjct: 840 PPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG 899 Query: 2416 LKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHP-GAP 2474 + G + + G+ P GP PG + K P GAP Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGP-------------PGPAGEKGSPGADGPAGAP 946 Query: 2475 AEPSPAALPAQQPLEPL----AQKCQPPRKKSHRVSGKERPNHSRGD--------PSHVT 2522 P P + Q+ + L ++ P GK+ P+ + G+ P + Sbjct: 947 GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006 Query: 2523 QPPPAQGSKEVLRAPGSP 2540 PP G + A GSP Sbjct: 1007 GPPGESGREGAPGAEGSP 1024 Score = 67.0 bits (162), Expect = 3e-10 Identities = 121/477 (25%), Positives = 158/477 (33%), Gaps = 109/477 (22%) Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488 GAPGQ LP +R R PG A G D P Sbjct: 296 GAPGQMGPR---GLPGERGRPGAPGPAGARGNDGATGAAGPP--------------GPTG 338 Query: 3489 PSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALE 3548 P+ G+P + + RG E P + P P P PA A G+ DG Sbjct: 339 PAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP---PGPAGAAGPAGNPGADG--- 392 Query: 3549 RPENEASPGSPGPLLQQALPLGASLPRPGARG----QDAEGKRAPLVFSGKRRAPGARGR 3604 +P + + G+PG + + PGARG Q G P SG+ APG++G Sbjct: 393 QPGAKGANGAPG--------IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKG- 443 Query: 3605 CAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS-K 3663 + E GP G P G R A P Sbjct: 444 -------------------DTGAKGEPGPVG------VQGPPGPAGEEGKRGARGEPGPT 478 Query: 3664 ALKFPVHPRKAVGS--------LAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTK 3715 L P R GS +A + G PA PK PG + + + PG K Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK 538 Query: 3716 --TGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLP-ARAQA--------KSCTKG 3764 TG P P + T P P+ P P P AR QA K Sbjct: 539 GLTGSPGSPGP-------DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE 591 Query: 3765 PREAGEQ---GPHGSLGPKEK-GESSTKRKKGQV-PGPARSES--VGSFG----RAPSAP 3813 P +AGE+ GP G++GP K GE+ + G P R E GS G P+ P Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651 Query: 3814 DKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQG 3870 P +Q P + P P + + PG + G A P+G Sbjct: 652 PGEAGKPGEQGVPGDL----------GAPGPSGARGERGFPGERGVQGPPGPAGPRG 698 Score = 62.8 bits (151), Expect = 7e-09 Identities = 106/437 (24%), Positives = 143/437 (32%), Gaps = 71/437 (16%) Query: 3483 LCSEVAPSTTKGWP--ETLERPVDPVTHPIRGCELPSNHQEC--PPPSLSPFPAALADGR 3538 LC +V TK P E E PV G E P++ + P P Sbjct: 69 LCDDVICDETKNCPGAEVPEGECCPVCPD--GSESPTDQETTGVEGPKGDTGPRGPRGPA 126 Query: 3539 GDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRA-----PLVFS 3593 G DG +P PG PGP L G + + G D + P+ S Sbjct: 127 GPPGRDGIPGQPGLPGPPGPPGPPGPPGL--GGNFAPQLSYGYDEKSTGGISVPGPMGPS 184 Query: 3594 GKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSK 3653 G R PG G P FQ E S GPRG P G + Sbjct: 185 GPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPM-----GPRG---------PPGPPGKNG 230 Query: 3654 DRSAASTPSK-ALKFPVHPRKAVG----SLAPGELAR-------GTENGMKPATPKAKPG 3701 D A P + + P P+ A G + PG G + PA PK +PG Sbjct: 231 DDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPG 290 Query: 3702 PSSQGSGSPRPGTKTGGGSQPQPAS----GQLQSETATTPAKPSFPSRSPAPERLPARAQ 3757 + + G + G + +P + G ++ AT A P P+ P P Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVG 350 Query: 3758 AKSCTKGPREAGEQGPHGSLGPK----EKGESSTKRKKGQVPGPARSESVGSFG------ 3807 AK EAG QGP GS GP+ E G G P G+ G Sbjct: 351 AKG------EAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404 Query: 3808 ----------RAPSAPDKP--PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 R PS P P P P+ + +K ++ +P P + G Sbjct: 405 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG 464 Query: 3856 HTQRKDRLGKAFPQGRP 3872 ++ G+ P G P Sbjct: 465 EEGKRGARGEPGPTGLP 481 Score = 59.7 bits (143), Expect = 6e-08 Identities = 286/1248 (22%), Positives = 366/1248 (29%), Gaps = 255/1248 (20%) Query: 1232 PGLLIPE-----------QPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGT 1280 PG +PE + P + TG P G P G + PG + G PG Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141 Query: 1281 QAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPV 1340 P PP G F P+ S + S+ G G P+G Sbjct: 142 GPPGPPGPPGPPG-LGGNF-----------APQLSYGYDEKSTGGISVPG----PMGPSG 185 Query: 1341 AKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGE-------- 1392 + P P +P + F GP G E P PP DGE Sbjct: 186 PRGLPGPPGAPGPQGFQGPPGEPG---EPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242 Query: 1393 DAGSLEPQLPRSPPGTA-------------------ETEPGRAASPPTLESSSLFP---- 1429 + G PQ R PGTA + P P + P Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG 302 Query: 1430 --DLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPP-YPSFLLLE-EVSPMLPS 1485 LP +R P G A + G A A PP T P+ PP +P + + E P P Sbjct: 303 PRGLPGERGRPGAPGPAGARGNDGATGA-AGPPGPTGPAGPPGFPGAVGAKGEAGPQGPR 361 Query: 1486 HFPDLSGGKVLSKTCPPERTVV------PGA-----------------APSLPG------ 1516 G V + PP PGA AP PG Sbjct: 362 GSEGPQG--VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419 Query: 1517 -KGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVG-RVELG-T 1573 +G G + E K T + + +G P E G R E G T Sbjct: 420 PQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE-PGPVGVQGPPGPAGEEGKRGARGEPGPT 478 Query: 1574 GTE-PPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPC 1632 G PP +R P F AD + A G+ +G PG Sbjct: 479 GLPGPPGERGG-----PGSRGFPGADGVAGPKGPAGERGSPGPAGP----KGSPG----- 524 Query: 1633 PASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDV 1692 + PG A LP A+ ++G+P SP G + P AG D RP Sbjct: 525 -EAGRPGEAG-LPGAKG--LTGSPGSP-GPDGKTGPPGPAGQ----------DGRP---- 565 Query: 1693 CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEP 1752 P PG + AG + P P ++ + G P Sbjct: 566 ---GPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622 Query: 1753 GTADQP-HRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWP--------FGASPSHAA 1803 G A RG P GSP P G PP +A P GA A Sbjct: 623 GPAGPAGERGEQGPA--GSPGFQGLP-----GPAGPPGEAGKPGEQGVPGDLGAPGPSGA 675 Query: 1804 QGHSA--GRAGGHLHPTAGRP----GFEGNEFAPAGASSLTAPRGREA-WLVPVPSPACV 1856 +G G G P P G GN+ A A + AP + A L +P Sbjct: 676 RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA 735 Query: 1857 SNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGT 1916 + + + A GP A G G++ LT P G +G + Sbjct: 736 AGLPGPKGDRGDA-----------GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGES 784 Query: 1917 VEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPE 1976 G A+G+PG P AG ADG G G+ +G A P Sbjct: 785 GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844 Query: 1977 NGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNR 2035 PG N + A GP GA G A P P PP P Sbjct: 845 GPAGPPGPIGNVGAPGAKGARGSAGP-PGATGFPGAAGRVGPPGPSGNAGP-PGPPGP-- 900 Query: 2036 ESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHM 2095 +G EG R + +P P G+ +P A Sbjct: 901 -------------AGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKG--SPGADGPAGA 945 Query: 2096 PCSLGPLPREDPLTSPSRAQGGLGGQ-----LPASPSCRDPPGPQQLLACSPAWAPLEEA 2150 P + GP + R GL GQ P P PG Q Sbjct: 946 PGTPGPQG-----IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ--------------- 985 Query: 2151 DGVQATTDTGAEDSPVAPPSLTTSPCDP-KEALAGCLLQGEGSPLEDPSSWPPGSVSAVT 2209 G + P+ PP L P + +E G EGSP D S G Sbjct: 986 -GPSGASGERGPPGPMGPPGLAGPPGESGREGAPG----AEGSPGRDGSPGAKGDRGETG 1040 Query: 2210 CTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPL--AGAVSPSVAVRATGLSSTPTGD 2267 P P +S R + P AG V P V R P GD Sbjct: 1041 PAGPPGAPGAPGAPGPVG----PAGKSGDRGETGPAGPAGPVGP-VGARGPAGPQGPRGD 1095 Query: 2268 EAQAGR-------------GLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREG 2314 + + G GL GP P G+P P P +A ++G Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGP-PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDG 1154 Query: 2315 QAVTAVPTEPPTLQG----AGPDSPACLEGEMGTSSKEPEDPGTPETG 2358 P PP +G AGP P G P PG P G Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGPPG-------PPGPPGPPSAG 1195 Score = 58.2 bits (139), Expect = 2e-07 Identities = 138/542 (25%), Positives = 171/542 (31%), Gaps = 115/542 (21%) Query: 3422 FRGVRRP-------GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSE 3474 F G R P G PG K + E P + G PGP + PP P E Sbjct: 411 FPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE-PGPVGVQGPP---GPAGEE 466 Query: 3475 GSLPALLHLCSEVAPSTTKGWPETLERPVD---PVTHPIRGCELPSNHQECPPPSLSPFP 3531 G A E P+ G P P P + G + P+ + P P+ Sbjct: 467 GKRGAR----GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522 Query: 3532 AALADGRGDCALDGALERPENEASPGS------PGPLLQQALPLGASLPRPGARGQDA-- 3583 A G+ L GA + SPG PGP Q P G P PGARGQ Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRP-GPPGP-PGARGQAGVM 580 Query: 3584 -----EGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFH 3638 +G +G+R PG G P K+ E + GP G Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGP--------AGKDGEAGAQGPPGPAGPAG--- 629 Query: 3639 KGSATKPAGCQSSSKDRSAASTPSKALKFPVH----------PRKAVGSLA-PGELARGT 3687 + PAG A P +A K P A G PGE RG Sbjct: 630 ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE--RGV 687 Query: 3688 ENGMKPATPKAKPG-PSSQGS----GSP-RPGTKTGGGSQPQP----ASGQLQSETATTP 3737 + PA P+ G P + G+ G+P PG++ G Q P A+G + Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD 747 Query: 3738 AKPSFPSRSPAPER---LPARAQAKSCTKGPREAGEQGPHGSLGPK-------------- 3780 A P SP + L P + GE GP G GP Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGP 807 Query: 3781 -----------------EKGESSTKRKKGQV--PGPARSES----VGSFGRAPSAPDK-- 3815 KGE KG PGPA +G+ G AP A Sbjct: 808 PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVG-APGAKGARG 866 Query: 3816 ---PPRTPRKQATPSRVLPTKPKPNS--QNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQG 3870 PP RV P P N+ P P E K G T R G+ P G Sbjct: 867 SAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG 926 Query: 3871 RP 3872 P Sbjct: 927 PP 928 Score = 47.8 bits (112), Expect = 2e-04 Identities = 176/707 (24%), Positives = 212/707 (29%), Gaps = 157/707 (22%) Query: 2632 RGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGET 2691 +G+R P A H G DG + GP +G + E G+ Sbjct: 250 QGARGLPGTAGLPGMKGH----RGFSGLDGAK----GDAGPAGPKGEPGSPGENGAPGQM 301 Query: 2692 GAQKPPGDRML--CPGRM-----DGAALGEQPTGQKG-ASARGFWGPRETKALGVCKESG 2743 G + PG+R PG DGA P G G A GF G A+G E+G Sbjct: 302 GPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG-----AVGAKGEAG 356 Query: 2744 SEPAEDSSRAHSRSEEGVWEENTPP-----LGPLGFPETSSSPADSTTSSC--LQGLPDN 2796 + S +GV E PP GP G P P + + G P Sbjct: 357 PQGPRGSE-----GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411 Query: 2797 PDTQG--GVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPG--GRLTRKRNPHVYGK 2852 P +G G QGP GP S P D + + P G G G Sbjct: 412 PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471 Query: 2853 RCEKPVLPLPTQPSFEEGG---------DPTLGPARLPTDLSDSSSLCLCHEDPWEDEDP 2903 R E LP P E GG D GP + P S P E P Sbjct: 472 RGEPGPTGLPGPPG-ERGGPGSRGFPGADGVAGP-KGPAGERGSPGPAGPKGSPGEAGRP 529 Query: 2904 --AGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEPSR--------EAGAEKLPSHCPED 2953 AGLP + L G S P PG + P +AG P Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA 589 Query: 2954 DRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPEPPSLER-ERCDGGLPGNTHLLP 3012 P E VP G PA D + + G P P+ ER E+ G PG Sbjct: 590 GEPGKAGE-RGVPGP-PGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG------ 641 Query: 3013 LRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQSRRTEEA-AGAG 3071 F+ L GP P P G + GP R E G Sbjct: 642 -----FQGLP-----------GPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGER 685 Query: 3072 RAQGRGRPAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPTCYMCVERRFGSREL- 3130 QG PA R A+ + G A P P GS+ Sbjct: 686 GVQGPPGPAGPRGAN----------GAPGNDGAKGDAGAPGAP-----------GSQGAP 724 Query: 3131 -LRGHLQERHAQSKAGPWACGMCLKEVADVWMYNEHLREHAVRFARRGQARRSLGDLPGG 3189 L+G ER A GP RG A D G Sbjct: 725 GLQGMPGERGAAGLPGPKG--------------------------DRGDAGPKGAD---G 755 Query: 3190 LEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARS 3249 G V L I P P G + +G P P G G +PG+R +P Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSG-PAGPTGARG-----APGDRGEPG--- 806 Query: 3250 TPSNPDGAATPDSAS-----------ATALADAGSPGPPRTTPSPSP 3285 P P G A P A A A DAG PGP P P Sbjct: 807 -PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP 852 Score = 41.6 bits (96), Expect = 0.016 Identities = 39/119 (32%), Positives = 46/119 (38%), Gaps = 25/119 (21%) Query: 3189 GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPG--------DPWGQEGEAKKDSPG 3240 G+ G A L P PK RG A GSPG P G G A +PG Sbjct: 728 GMPGERGAAGL------PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPA--GAPG 779 Query: 3241 ERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299 ++ + S P G A P A A D G PGPP P P A G+P + P Sbjct: 780 DKGE-------SGPSGPAGPTGARG-APGDRGEPGPPGPAGFAGP-PGADGQPGAKGEP 829 Score = 36.2 bits (82), Expect = 0.66 Identities = 26/105 (24%), Positives = 34/105 (32%) Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPR 3246 P G G + + E P+ RG G PG P +PG +P Sbjct: 336 PTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPG 395 Query: 3247 ARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGG 3291 A+ P A P A + PG P S +P A G Sbjct: 396 AKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG 440 Score = 36.2 bits (82), Expect = 0.66 Identities = 33/110 (30%), Positives = 39/110 (35%), Gaps = 12/110 (10%) Query: 3209 KHHRGKRSAGKAAGSPGDPWGQEGEAKKDSP-GERAKPRARSTPS--------NPDGAAT 3259 K HRG G PG P G++G + P G R P + P P G Sbjct: 1108 KGHRGFSGLQGPPGPPGSP-GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG 1166 Query: 3260 PDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPVHEACKDPSR 3309 P + A G PGPP P P P AG + P E D R Sbjct: 1167 PRGRTGDA-GPVGPPGPP-GPPGPPGPPSAGFDFSFLPQPPQEKAHDGGR 1214 Score = 35.4 bits (80), Expect = 1.1 Identities = 38/150 (25%), Positives = 54/150 (36%), Gaps = 11/150 (7%) Query: 3177 GQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKK 3236 G A + G P G G + + P P +G A AG+PG P G +G A + Sbjct: 899 GPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP-GPQGIAGQ 957 Query: 3237 DS----PGERAKPRARSTPSNPDGAATPDSASAT-ALADAGSPGP--PRTTPSPSPDPWA 3289 PG+R + R P P + P + A + G PGP P P + Sbjct: 958 RGVVGLPGQRGE---RGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGR 1014 Query: 3290 GGEPLLQATPVHEACKDPSRDCHHCGKRFP 3319 G P + +P + D G P Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGP 1044 Score = 35.0 bits (79), Expect = 1.5 Identities = 39/112 (34%), Positives = 44/112 (39%), Gaps = 30/112 (26%) Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRG-------KRSAGKAA--GSPGDPWGQEGE---- 3233 P G G A L P K HRG K AG A G PG P G+ G Sbjct: 249 PQGARGLPGTAGL------PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSP-GENGAPGQM 301 Query: 3234 AKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285 + PGER +P A P GA D A+ AG PGP T P+ P Sbjct: 302 GPRGLPGERGRPGA----PGPAGARGNDGATGA----AGPPGP--TGPAGPP 343 Score = 34.7 bits (78), Expect = 1.9 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 8/83 (9%) Query: 3203 ITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDS 3262 I+ P P G R G+PG P G +G PGE +P A S P P G P Sbjct: 175 ISVPGPMGPSGPRGLPGPPGAPG-PQGFQG-----PPGEPGEPGA-SGPMGPRGPPGPPG 227 Query: 3263 ASATALADAGSPGPPRTTPSPSP 3285 + +AG PG P P P Sbjct: 228 KNGDD-GEAGKPGRPGERGPPGP 249 Score = 33.1 bits (74), Expect = 5.6 Identities = 33/118 (27%), Positives = 37/118 (31%), Gaps = 17/118 (14%) Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDP-----WGQEGEAKKDS--- 3238 P G GS A S E G A GSPG P G G A +D Sbjct: 507 PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPG 566 Query: 3239 ----PGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGE 3292 PG R + P A P A + G PGPP D AG + Sbjct: 567 PPGPPGARGQAGVMGFPGPKGAAGEPGKA-----GERGVPGPPGAVGPAGKDGEAGAQ 619 Score = 32.7 bits (73), Expect = 7.3 Identities = 35/123 (28%), Positives = 41/123 (33%), Gaps = 17/123 (13%) Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGS------PGDPWGQEGEAKKDSPG 3240 P G +GS + P P+ G+R G PG P G GE K P Sbjct: 930 PAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP-GPSGEPGKQGPS 988 Query: 3241 ERAKPRARSTPSNPDGAATPDSASATALADA--------GSPGPP--RTTPSPSPDPWAG 3290 + R P P G A P S A GSPG R P+ P A Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048 Query: 3291 GEP 3293 G P Sbjct: 1049 GAP 1051 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 103 bits (256), Expect = 4e-21 Identities = 311/1313 (23%), Positives = 406/1313 (30%), Gaps = 268/1313 (20%) Query: 28 GHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQ------ 81 G P P L P T T G + G LP + + G PP L G Sbjct: 337 GPPGPPGLVIPRPGTGITIGEK---GNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393 Query: 82 ---APSSTPGKRGSP--QTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDE- 135 P PG+RG + PPG S + P L G+ G+P G A P+ DE Sbjct: 394 GPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQP-GAPGLPGPPGPAGPHIPPS-DEI 450 Query: 136 ----------TPENPQLEAAQLPEVDTPQ------GPG-TGAPLRPGLPRTEAQPAAEEL 178 +P + L+ Q + D G G +G P +PGLP P + L Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS--L 508 Query: 179 GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPA 238 GF E + + P P APG P S+G +PG + D Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG----EPGDILTFPGMKGDK---- 560 Query: 239 AENSFPGANFGVP--PAEP--EPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAG 294 E PGA G+P P P + +P P G P G++F+ G P + G Sbjct: 561 GELGSPGAP-GLPGLPGTPGQDGLPGLPGPKGEPGGITFK-------GERGPPGNPGLPG 612 Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGA 354 GP+ P G P VG + P +P +G PG G Sbjct: 613 LPGNIGPM-----GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667 Query: 355 LSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRAS 414 +PG P L P +P G+ ++G P +P PG Sbjct: 668 PGNPGRDGDVGLPGDPGL--------PGQP--GLPGIPGSKGEPG-IPGIGLPGPP-GPK 715 Query: 415 GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPS-PGQR 473 G PGPP APG P R+ P +P P G P A G P PG + Sbjct: 716 GFPGIPGPP----GAPGTP-GRIGLEGPPGPPGFPGPKGEPGFALPGP--PGPPGLPGFK 768 Query: 474 LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAG--GPEWQGGSQGALGTAG----KT 527 L +P P P G L LP P G GP Q G G G G Sbjct: 769 GALGPKGDRGFP-----GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 528 PGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVG-- 585 PGP G+ P QP G+ + P G P L P G Sbjct: 824 PGPP--------------------GIPGPIGQPGLHGIPGEKGDP-GPPGLDVPGPPGER 862 Query: 586 ASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETG 645 SP P P + P S + S PG G PP P G Sbjct: 863 GSPGIPGAPGP-----------IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911 Query: 646 SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGF 705 P S P Q +P P P G++G L P P + +G G +G Sbjct: 912 IPGRSGVPGLKGDDGLQGQPG--LPGPTGEKGSKGE-PGLPGPPGPMDPNLLGSKGEKGE 968 Query: 706 PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQ 765 P P + + + GL + G Sbjct: 969 PGLP--------------------------------GIPGVSGPKGYQGLPGDPGQPGLS 996 Query: 766 RSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGD---AQAEGKDDPLRTGFLPSLAA 822 PG PG P P P +P GL+ GD +G + P +P Sbjct: 997 GQPGLPGPPGPKGNPGLP--GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054 Query: 823 TPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSG 882 +P LP D + D + S+ L G + + P + G +G S G Sbjct: 1055 SP-GLPGQKGD-KGDPGISSIGLPGLPGPKGEPGLPGYPGN----------PGIKG-SVG 1101 Query: 883 HPLKSKAGVTPESKAPPPLPA--ATPDPQTPR-----PGDRGCPARGRPKTRSLGLAPTE 935 P TP +K P LP TP P P+ PG+ G P G P G P + Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP--GEPGPVGGGGHPGQ 1159 Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPR 995 P G + + G+ G G+ G GL ++ DG P P Sbjct: 1160 PGPP--GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG 1217 Query: 996 RPRTQA-------------PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042 P + PG P P + P R LP + P Sbjct: 1218 LPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGN 1277 Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGP 1102 GG G E+ P PG G +G QGP Sbjct: 1278 GGIKG-----------------------EKGNPGQPGLPGLPGLKG----------DQGP 1304 Query: 1103 REDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPK 1162 + R G G P P PG GP P + GP EG P Sbjct: 1305 PGLQGNPGRPGLNGMKGDPGLPGVPGFPG--MKGPSGVPGSAGP-----------EGEPG 1351 Query: 1163 CADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPA 1222 + P P +P + S + P +P P + PP Sbjct: 1352 L-----IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1406 Query: 1223 ----------ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSS 1265 AG PGL P Q P +R G P P G P G+S Sbjct: 1407 DPGRNGLPGFDGAGGRKGDPGL--PGQ-PGTRGLDGPPGPDGLQGPPGPPGTS 1456 Score = 85.5 bits (210), Expect = 9e-16 Identities = 193/783 (24%), Positives = 245/783 (31%), Gaps = 176/783 (22%) Query: 16 GDLQPRQVASSPGHPSQP--PLEDNTPATRTT----KGAREAGGQAQAMELPEAQPRQAR 69 G P+ + PG P P P P T KG + G A LP + Sbjct: 521 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQ 580 Query: 70 DGELKPPSLRGQAPSST-PGKRGSPQTP--PGRSPLQAPSRLAGRAEGSPP-QRYILGIA 125 DG P +G+ T G+RG P P PG P G P ++ I G+A Sbjct: 581 DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA 640 Query: 126 SSRTKPTLDETPENPQLEAAQLPEVDTPQGPGT-------------GAPLRPGLPRTEAQ 172 + +P + +P Q + P PG G P PG+P ++ + Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700 Query: 173 PAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPA-------PGPPQSRGTSPLQPGSYP 225 P +G PP P P P PGPP G P P Sbjct: 701 PGIPGIGL----PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG-----PKGEP 751 Query: 226 EYQASGADSWP----------PAAENSFPGANFGVPPAEPE-------PIPKGS-RPGGS 267 + G P P + FPG PP P P PKG P G Sbjct: 752 GFALPGPPGPPGLPGFKGALGPKGDRGFPG-----PPGPPGRTGLDGLPGPKGDVGPNGQ 806 Query: 268 PR--------GVSFQFPF--PALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEA 317 P G+ Q P P + G +P + G GP P G Sbjct: 807 PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG 866 Query: 318 VGTGPAYPLPTQPAPSP-LPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSL 376 + P P P P SP LP G G ++ G + PG P P + Sbjct: 867 I---PGAPGPIGPPGSPGLPGKAGASGFPGTKGEM-GMMGPPGP----PGPLGIPGRSGV 918 Query: 377 TKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAA------- 429 + + Q GL G S + PG PGP D L Sbjct: 919 PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP----------PGPMDPNLLGSKGEKGE 968 Query: 430 PGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489 PG P +P + P Y PG P GQP L LP P Sbjct: 969 PGLPG--IPGVSGPKG--YQGLPGDP----------GQPG------LSGQPGLPGP---- 1004 Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR----EKLPAVRSSQGGSP 545 P P G L P G P G +G +G G PGP+ P+ Q GSP Sbjct: 1005 ---PGPKGNPGLPGQPGLIGPP----GLKGTIGDMG-FPGPQGVEGPPGPSGVPGQPGSP 1056 Query: 546 ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTC 605 L G D G P +S G P LP P+ E LP N Sbjct: 1057 GLPGQKG--DKG---------DPGISSIGLPGLPGPK------GEPGLPGYPGNPGIKGS 1099 Query: 606 SSLSPMSSSPANPSSEESQ-------LPGPLGPSAFFHPPTHPQETGSPFP---SPEPPH 655 + P P ++ PGP GP PP +P G P P P Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159 Query: 656 SLPTHYQPEPAK-AFPFPADGLGAEGAFQCLEETPFPHEGP--------EVGRGGLQGFP 706 P + +P + P PA G G + F + GP + G GGL G P Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPG------QPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213 Query: 707 RAP 709 P Sbjct: 1214 GNP 1216 Score = 78.2 bits (191), Expect = 2e-13 Identities = 175/691 (25%), Positives = 225/691 (32%), Gaps = 128/691 (18%) Query: 1 MPGERPRGAPP----PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQ 56 +PGE+ PP P G+ + +PG P PP P G G+ Sbjct: 841 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMG 899 Query: 57 AMELPEAQPRQARDGELKPPSLRGQ----------APSSTPGKRGSPQTPPGRSPLQAPS 106 M P G P L+G P+ G +G P P P+ P+ Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-PN 958 Query: 107 RLAGRAE-GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG 165 L + E G P I G++ + L P P L P + P GP G P PG Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ--PGLPGPPGP-KGNPGLPG 1015 Query: 166 LPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSY- 224 P P + + + P PP P + SP PG Sbjct: 1016 QPGLIGPPGLK------------GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKG 1063 Query: 225 ----PEYQASGADSWP-PAAENSFPG--ANFGVPPAEPEPIPKGSRPG--GSPRGVSFQF 275 P + G P P E PG N G+ + +P PG G+P G Q Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP----GLPGLPGTP-GAKGQP 1118 Query: 276 PFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPL 335 P G P P ++G G P P VG G P QP P Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPG-------LPGEPGP---VGGGGH---PGQPGP--- 1162 Query: 336 PCYQGQPG--GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGS 393 P +G+PG G+ + G PG + P + LP P GL Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP--GNPGLPG 1220 Query: 394 TRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT-PP 452 +G P FPG GPP GPP + P L P P P PP Sbjct: 1221 PKGEPGF---HGFPGVQ----------GPP-------GPPGSPGPALEGPKGNPGPQGPP 1260 Query: 453 G--------GPLAATRSMFFNGQP-SPGQRLCLPQSAPLPWPQVLP-----TARPSPHGM 498 G GP + G+ +PGQ LP L Q P RP +GM Sbjct: 1261 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQP-GLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1319 Query: 499 EMLSRLPFPAGGPEWQG--GSQGALGTAGK-----TPGPREKLPAVRSSQGGSPALFTYN 551 + LP G P +G G G+ G G+ PGP P + G S + Sbjct: 1320 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP----PGLPGPSGQSIIIKGDA 1375 Query: 552 GMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPM 611 G QP G+ PQ G LP P P + L P + AG Sbjct: 1376 GPPGIPGQPGLKGLPGPQ----GPQGLPGPTGPPGDPGRNGL--PGFDGAGG-------R 1422 Query: 612 SSSPANPSSEESQ-LPGPLGPSAFFHPPTHP 641 P P ++ L GP GP PP P Sbjct: 1423 KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1453 Score = 71.2 bits (173), Expect = 2e-11 Identities = 371/1591 (23%), Positives = 469/1591 (29%), Gaps = 326/1591 (20%) Query: 2 PGERPR----GAP-PPTMTGDLQPRQVASSPGHPSQP--PLEDNTPATRTTKGAREAGGQ 54 PG R + G P PP G P + PG P P P D P + G G+ Sbjct: 71 PGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130 Query: 55 AQAMELPEAQPRQARDGELKPPSLRGQAPS----STPGKRGSP--QTPPGRSPLQAPSRL 108 P Q G P ++G+ S S PG +G+P PPG L P+ + Sbjct: 131 RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGI 190 Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168 G P G+ P L N L Q P+ + + G P PG Sbjct: 191 PGPIGPPGPP----GLMGPPGPPGLPGPKGNMGLNF-QGPKGEKGEQGLQGPPGPPGQIS 245 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228 + +P E F + Q P R P PGPP RG PG Sbjct: 246 EQKRPIDVE--FQKGDQGLPGD-------------RGP-PGPPGIRGP----PG------ 279 Query: 229 ASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF 288 PP E G G P +P G G P G+ P G + Sbjct: 280 -------PPGGEKGEKGEQ-GEPGKRGKPGKDGEN--GQP-GIPGLPGDPGYPGEPGRDG 328 Query: 289 PADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348 G GP +P G LP + P QG PG Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG----- 383 Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS--AQDGLGSTRGPPSSLPQRHF 406 L G PGAA P PP + G GPP Sbjct: 384 --LPGP---PGAAVMGP----------------PGPPGFPGERGQKGDEGPPGI----SI 418 Query: 407 PGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG 466 PG G+D PG P PGPP P + P PPG P + Sbjct: 419 PGPP----GLDGQPGAP----GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470 Query: 467 QPSPGQR--LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTA 524 Q G + C + T P G L LP P G + G +G G A Sbjct: 471 QGVKGDKGDTCF---------NCIGTGISGPPGQPGLPGLPGPPGSLGFPG-QKGEKGQA 520 Query: 525 GKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVA--QPQVSPHGTPSLPPPR 582 G T GP+ LP + + G +P G +PG F G+ + ++ G P LP Sbjct: 521 GAT-GPKG-LPGIPGAPG-APGFPGSKG--EPGDILTFPGMKGDKGELGSPGAPGLPGLP 575 Query: 583 VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPG---PLGPSAFFHPPT 639 LP P G T +P P LPG P+GP F P Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG-----LPGNIGPMGPPGFGPPGP 630 Query: 640 -----------HPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEET 688 +P + G P P +P ++ +P P +G G + Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG-LPGNPGRDGDVGLPGDPGLPGQP 689 Query: 689 PFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLA 748 P G G+ G PP P + Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP------------------------- 724 Query: 749 HRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGK 808 G + G + PGPPG P P P F L G G Sbjct: 725 -----GAPGTPGRIGLEGPPGPPGFPGPKGEPG---------------FALPGPPGPPGL 764 Query: 809 DDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVF 868 P G L FP P LD L P+ Sbjct: 765 --PGFKGALGPKGDRGFPGPPGP---PGRTGLDGL------------PGPK--------- 798 Query: 869 ADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPA-RGRPKTR 927 D P+G GP G P GV PP P P P +PG G P +G P Sbjct: 799 GDVGPNGQPGPM-GPPGLPGIGVQG-----PPGPPGIPGP-IGQPGLHGIPGEKGDPGPP 851 Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLG 987 L + + S G G G G G ASG P +G Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPI-----------GPPGSPGLPGKAGASGF-PGTKGEMG 899 Query: 988 ERPPPRPRRP-----RTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042 PP P P R+ PG + D + LP T + P P Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDG--LQGQPGLPGPTGEKGSKGEPGLPGPP----- 952 Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGP 1102 G L+ S+ E+ E P PG G +G QG Sbjct: 953 -GPMDPNLL---------------GSKGEKGEPGLPGIPGVSGPKGY----------QGL 986 Query: 1103 REDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLE-TGAAAREGGP 1161 D Q G G NP PG +PG P +G + G EG P Sbjct: 987 PGDPGQPGLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLD------FPQEAKEPETAEESAPDSTEFTE 1215 PS P P + ++ P + P EP P + Sbjct: 1045 G----PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP--GYPGNPGIKG 1098 Query: 1216 ALRSPPA-ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLL 1274 ++ P G GA +P P GTP P G + P G+ PG + Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPKGISGPPGNPGLPGEPGPV 1151 Query: 1275 GGPG--GTQAPVSHNSK------DPPARQPGEFLAP-VANPSSTACPKPSVLSSK--ISS 1323 GG G G P K PA Q GE P NP P S + Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPG 1211 Query: 1324 FGCDPA--GFNRDP--LGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDA 1379 +P G +P G P + P P SP L GPK G P + Sbjct: 1212 IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL-EGPKGNPGPQGPPGRPGLPGPEG 1270 Query: 1380 PPASSSCLCQDGEDAGSLEPQLP--------RSPPGTAETEPGRAASPPTLESSSLFPDL 1431 PP GE +P LP + PPG + PGR P L P L Sbjct: 1271 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG-LQGNPGR----PGLNGMKGDPGL 1325 Query: 1432 PVDRFDPPLYGSLSANRDSGLPFAC---ADPPQKTVPSDP--PYPSFLLLEEVSPMLPSH 1486 P P + G SG+P + +P P P P PS + P Sbjct: 1326 PGVPGFPGMKG------PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG 1379 Query: 1487 FPDLSGGKVLSKTCPPERTVVPGAAPSLPGK 1517 P G K L P+ P P PG+ Sbjct: 1380 IPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR 1410 Score = 69.3 bits (168), Expect = 7e-11 Identities = 316/1310 (24%), Positives = 398/1310 (30%), Gaps = 204/1310 (15%) Query: 309 PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGA-AHSAP 365 P+G ++ + GP P + P LP + G PG G+ H G PG Sbjct: 73 PRGQKGDDGI-PGPPGPKGIRGPPG-LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130 Query: 366 RPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT 425 R F S P P GL GPP + PG +S PGP Sbjct: 131 RGFPGS---------PGFP-----GLQGPPGPPGIPGMKGEPGSIIMSS----LPGPKGN 172 Query: 426 ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLP-------- 477 PGPP + L PT P P P GP G P P + L Sbjct: 173 P-GYPGPPG--IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229 Query: 478 -----QSAPLPWPQVLPTARP----------------SPHGMEMLSRLPFPAGGPEWQGG 516 Q P P Q+ RP P G + P P GG + + G Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289 Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPG--AQPLFFGVAQPQVSPHG 574 QG G GK PG + + G P + G DPG +P G + Q G Sbjct: 290 EQGEPGKRGK-PG--------KDGENGQPGIPGLPG--DPGYPGEPGRDG-EKGQKGDTG 337 Query: 575 TPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634 P PP +V +P P T G T + E PG GP Sbjct: 338 PPG--PPGLV--------IPRPGT---GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL 384 Query: 635 FHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEG 694 PP G P P P + P + P P GL + L P P G Sbjct: 385 PGPP-GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLDGQPGAPGLPGPPGP-AG 441 Query: 695 PEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQLDVLLTCRQC-------DRNYSSLAAF 746 P + P P PP L + D TC C L Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501 Query: 747 LAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPA-DAHAGLLSHAKTFL-LAGDAQ 804 G + + G + GP GLP P AP P G TF + GD Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561 Query: 805 AEGKDDPLRTGFLPSLAATPFP--LPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDS 862 G P G LP L TP LP + + G NP + Sbjct: 562 ELG--SPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGI------TFKGERGPPGNPGLPG 612 Query: 863 SFIDVFADEEPS-GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDP-----QTPRPGDR 916 ++ P GP GP ++ AG + P +P DP Q +PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAG----NPGQPGIPGPKGDPGQTITQPGKPGLP 668 Query: 917 GCPAR----GRPKTRSLGLAPTEADAP-SQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971 G P R G P L P P S+G G L G G+ G Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRL 1030 GL E PP P P + PG P P R Sbjct: 729 TPGRIGL---------EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 1031 PPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRG 1090 P P R G G + + Q + + PP PG G+ G Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839 Query: 1091 EKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL 1150 E P D P P R G GAP P P GS PG++ + P Sbjct: 840 GIPGEKGDPGPPGLDVPGPP--GERGSPGIPGAP-GPIGPPGSPGLPGKAGASGFPGTKG 896 Query: 1151 ETGAAAREGG------PKCADRPSVAPKDPLQ----VPTNT-ETSEETRPSLDFPQEAKE 1199 E G G P + P + D LQ +P T E + P L P + Sbjct: 897 EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956 Query: 1200 P-------ETAEESAP-----DSTEFTEALRSPPAACAGEMGAS--PGLLIPEQP----- 1240 P E E P + + L P G+ G S PGL P P Sbjct: 957 PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP----GQPGLSGQPGLPGPPGPKGNPG 1012 Query: 1241 -PPSRHDTGTPKPSGSLAN---TAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQ- 1295 P G P G++ + P G PG + G PG P K P Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072 Query: 1296 ---PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPH 1352 PG P P P + + DP G P G P AK P P Sbjct: 1073 IGLPG-LPGPKGEPGLPGYPGNPGIKGSVG----DP-GLPGLP-GTPGAKGQPGLPGFPG 1125 Query: 1353 SELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETE 1412 + GPK ++G PP + + G G P P PPG + + Sbjct: 1126 TPGPPGPKGISG---------------PPGNPGLPGEPGPVGGGGHPGQP-GPPG-EKGK 1168 Query: 1413 PGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANR-DSGLPFACADPPQKTVPSDPPYP 1471 PG+ P PP LS + D GLP +P +P + Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228 Query: 1472 SFLLLEEVSPMLPSHFPDLSGGK-VLSKTCPPERTVVPG--AAPSLPGKG 1518 F ++ S P L G K PP R +PG P LPG G Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNG 1278 Score = 57.8 bits (138), Expect = 2e-07 Identities = 134/539 (24%), Positives = 157/539 (29%), Gaps = 130/539 (24%) Query: 12 PTMTGDLQPRQVASSPGHPSQPPL--EDNTPATRTTKGAREAGGQAQAMELPEAQPRQAR 69 P + G P+ PG P QP L + P KG GQ + P + Sbjct: 972 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031 Query: 70 DGELKPPSLRGQ-APSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSR 128 G P + G PS PG+ GSP P + P + G P G+ + Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI---SSIGLP------GLPGPK 1082 Query: 129 TKPTLDETPENPQLEAAQLPEVDTPQGPGT-GAPLRPGLPRTEAQPAAEELGFHRCFQEP 187 +P L P NP ++ + + + P PGT GA +PGLP P P Sbjct: 1083 GEPGLPGYPGNPGIKGS-VGDPGLPGLPGTPGAKGQPGLPGFPGTPG------------P 1129 Query: 188 PSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP-PAAENSFPGA 246 P + P P P P G P QPG E G D P PA + PG Sbjct: 1130 PGP---KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQ 1186 Query: 247 -NFGVP--------------------PAEPE-PIPKGSR----------PGGSPRGVSFQ 274 FG P P P P PKG P G P Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS---- 1242 Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTG-PAYP-LPTQPAP 332 P PAL G P P G GP G E G P P LP Sbjct: 1243 -PGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1301 Query: 333 SPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS- 386 P QG PG G+ L G PG + P S I P PP Sbjct: 1302 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1361 Query: 387 --------------------AQDGLGSTRGP--PSSLP---------------------- 402 Q GL GP P LP Sbjct: 1362 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1421 Query: 403 ---QRHFPGQAYRAS--------GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT 450 PGQ G+ PGPP T A G R Q D P T Sbjct: 1422 RKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1480 Score = 53.5 bits (127), Expect = 4e-06 Identities = 263/1154 (22%), Positives = 343/1154 (29%), Gaps = 270/1154 (23%) Query: 1751 EPGTADQPHR----GAPA-PEAFGSPAVHLAP----DLAFQGDGAPPLDATWPFGASPSH 1801 EPG +P + G P P G P P + +GD PP P G Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPP----GPPGLVIPR 348 Query: 1802 AAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVSNT 1859 G + G G P G PG +G P G L P G P P Sbjct: 349 PGTGITIGEKGNIGLP--GLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG------ 400 Query: 1860 HPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPS--------- 1910 P R Q PP + +PGP + G GL P + P + PS Sbjct: 401 FPGERGQKGDEGPP--GISIPGPPGLDGQPGAPGLPG--PPGPAGPHIPPSDEICEPGPP 456 Query: 1911 ---------GLEGGT-VEGGK---------VACGPAQGSPGGVQVTTLPAVAGHQLGLEA 1951 GL+G V+G K G PG LP + G L Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPG------LPGLPGPPGSLGF 510 Query: 1952 DGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKC 2011 G G GQA T +G P +PG S P LT P Sbjct: 511 PGQKGEKGQAGATGPKGL-----PGIPGAPGAPGFPGS-KGEPGDILTFPG--------M 556 Query: 2012 KGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLAT 2071 KG + + SP +P L TP + PGL P Sbjct: 557 KGDKGELG---------SPGAPGLPGLP--------------GTPGQDGLPGLPGPK--- 590 Query: 2072 GDSPAPSVGDLAACAPSPTSAAHMPCSLGPL--PREDPLTSPSRAQG--GLGGQLPASPS 2127 P P +P ++GP+ P P P +G G+ G P P Sbjct: 591 -GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP-PGPVGEKGIQGVAGN-PGQPG 647 Query: 2128 CRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAP--PSLTTSPCDPKE-ALAG 2184 P G P L G D G P P P L P E + G Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDG--DVGLPGDPGLPGQPGLPGIPGSKGEPGIPG 705 Query: 2185 CLLQGEGSPLEDPS-SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243 L G P P PPG+ P P+ L PG P Sbjct: 706 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765 Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSP 2303 GA+ P GD RG PGP G P T D +P P Sbjct: 766 GFKGALGPK-------------GD-----RGFPGPP----GPPGRTGLDGLPGPKGDVGP 803 Query: 2304 SNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK-----EPEDPGTP--- 2355 + GQ P P + GP P + G +G E DPG P Sbjct: 804 N---------GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD 854 Query: 2356 ---ETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLG 2412 G G+ +P P +G +P S P + P G P G Sbjct: 855 VPGPPGERGSPGIPGAPGP-----IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP-G 908 Query: 2413 PQDLKQRS-----------RGYKKKPASTENGQWKGQ----APHGPVTCEVCAASFRSG- 2456 P + RS +G P T KG+ P GP+ + + G Sbjct: 909 PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE 968 Query: 2457 ------PGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKER 2510 PG+S K ++ PG P +P + P G Sbjct: 969 PGLPGIPGVSGPKG--YQGLPGDPGQPGLSGQP-----------------------GLPG 1003 Query: 2511 PNHSRGDPSHVTQP----PPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRP 2566 P +G+P QP PP G K + G P Q + P P P Sbjct: 1004 PPGPKGNPGLPGQPGLIGPP--GLKGTIGDMGFPGPQGVEGP-----------PGPSGVP 1050 Query: 2567 DQAREDELHPKQAEKREGRRWRREPTVDS---PSHSEGKSNKKRGKLRGRRLREESILPV 2623 Q L ++ +K + P + S P K G + S+ Sbjct: 1051 GQPGSPGLPGQKGDKGD-------PGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103 Query: 2624 SADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLG-PGVMEGAAETD 2682 + G++ P + + +P GP+ P G PG + G Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPG-----PPGPKGISGPPGNPGLPGEPGPVGGG---- 1154 Query: 2683 QEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGASAR-GFWGPRETKALGVCKE 2741 G G PPG++ PG+ DG P GQKG + GF P G+ + Sbjct: 1155 ------GHPGQPGPPGEKGK-PGQ-DGIP---GPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203 Query: 2742 SGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPAD-STTSSCLQGLPDNPDTQ 2800 G D G+ P G GFP P + L+G NP Q Sbjct: 1204 KG-----DGGLPGIPGNPGLPGPKGEP-GFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257 Query: 2801 G-----GVQGPEGP 2809 G G+ GPEGP Sbjct: 1258 GPPGRPGLPGPEGP 1271 Score = 52.0 bits (123), Expect = 1e-05 Identities = 117/458 (25%), Positives = 144/458 (31%), Gaps = 74/458 (16%) Query: 3425 VRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLC 3484 + +PG PG L G P + V +PG PG+ P G E +P + Sbjct: 659 ITQPGKPG-----LPGN-PGRDGDVGLPGDPGLPGQPGLP--GIPGSKGEPGIPGI---- 706 Query: 3485 SEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALD 3544 P KG+P P P T G E P P P P AL G L Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP-GFALPGPPGPPGLP 765 Query: 3545 G---ALERPENEASPGSPGPLLQQALPLGASLPRP----GARGQDAEGKRAPLVFSGKRR 3597 G AL + PG PGP + L LP P G GQ L G + Sbjct: 766 GFKGALGPKGDRGFPGPPGPPGRTGLD---GLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822 Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSA 3657 PG G P H + EK + GP G +GS P Sbjct: 823 PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG--ERGSPGIPG----------- 869 Query: 3658 ASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717 A P P P KA S PG T+ M P PGP S PG K Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPG-----TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 3718 GGSQPQPA-------SGQLQSETATTPAKPSFPS--------RSPAPERLPARAQAKSCT 3762 G Q QP G P P P+ P +P + K Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 3763 KGPREAGEQGPHGSLG----PKEKGESSTKRKKGQVPGPARSESVGSFG-RAPSAPDKPP 3817 P + G+ G G G P KG + G + P ++G G P + PP Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 PS V P P P + K +PG Sbjct: 1045 -------GPSGV------PGQPGSPGLPGQKGDKGDPG 1069 Score = 51.6 bits (122), Expect = 2e-05 Identities = 170/687 (24%), Positives = 226/687 (32%), Gaps = 102/687 (14%) Query: 871 EEPSGPRGPSSGHPLKSKAGVTPES-KAPPPLPAATPDPQTP-RPGDRGCPA-RGRPKTR 927 E P GPRG + G P+ + PP LP P P PG G P +G P Sbjct: 68 EGPPGPRGQKGDDGIPGPPG--PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIP--- 122 Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR-PRRNDGL 986 G T+ + G G Q G G G S L P+ N G Sbjct: 123 --GCNGTKGERGFPGSPGFPGLQ-----GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY 175 Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046 P + T PG P P P + + P+ K G Sbjct: 176 PGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235 Query: 1047 GKELILKIVQQKNRLREYDFASESE--EDEQPPPRGPGFRGRRG--RGEKRKEVELTQGP 1102 G + ++ R + +F + ++ PP PG RG G GEK ++ E Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----- 290 Query: 1103 REDEPQKPRKAARQ-EAGGDGAPANPEEPGGSRPG-PGRSPQARGPSRSLETGAAAREG- 1159 + EP K K + E G G P P +PG PG PGR + + +TG G Sbjct: 291 -QGEPGKRGKPGKDGENGQPGIPGLPGDPG--YPGEPGRDGE---KGQKGDTGPPGPPGL 344 Query: 1160 -GPKCADRPSVAPKDPLQVP-TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217 P+ ++ K + +P E E P + P P A P Sbjct: 345 VIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG------- 397 Query: 1218 RSPPAACAGEMG-----ASPGLLIPEQP-----PPSRHDTGTPKPSG-------SLANTA 1260 P GE G PG+ IP P P + G P P+G + Sbjct: 398 ---PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454 Query: 1261 PHGSSPTPGVGSLLGGPG--GTQAPVSHN----SKDPPARQPGEFLAPVANPSSTACPKP 1314 P G +PG L G G G + N P QPG P P S P Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP-GPPGSLGFPGQ 513 Query: 1315 SVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL-FLGPKDLAGCFLEELHPK 1373 + + G P G P G P A P P L F G K G EL Sbjct: 514 KGEKGQAGATG--PKGLPGIP-GAPGAPGFPGSKGEPGDILTFPGMKGDKG----EL-GS 565 Query: 1374 PSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPG--TAETEPGRAASPPTLESSSLFPDL 1431 P A P + G+D P P+ PG T + E G +P P L Sbjct: 566 PGAPGLPGLPGT----PGQDGLPGLPG-PKGEPGGITFKGERGPPGNPG-------LPGL 613 Query: 1432 P--VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD 1489 P + PP +G + G+ +P Q +P P + + P LP + P Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN-PG 672 Query: 1490 LSGGKVLSKTCPPERTVVPGAAPSLPG 1516 G L P +PG P LPG Sbjct: 673 RDGDVGL-----PGDPGLPG-QPGLPG 693 Score = 49.7 bits (117), Expect = 6e-05 Identities = 120/515 (23%), Positives = 165/515 (32%), Gaps = 81/515 (15%) Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLP 3478 P ++G+ PG PGQ + + LP PG PG PP G + + P Sbjct: 980 PKGYQGL--PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP--GLKGTIGDMGFP 1035 Query: 3479 ALLHLCSEVAPSTTKGWPETLERPV------DPVTHPIRGCELPSNHQECPPPSLSPFPA 3532 + PS G P + P DP I LP E P L +P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE---PGLPGYP- 1091 Query: 3533 ALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG-------QDAE 3584 G+ + G++ P PG+PG Q LP P PG +G Sbjct: 1092 ------GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145 Query: 3585 GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATK 3644 G+ P+ G PG G E ++ + E G G + G Sbjct: 1146 GEPGPVGGGGHPGQPGPPG--------EKGKPGQDGIPGPAGQKGEPGQPGFGNPG---- 1193 Query: 3645 PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSS 3704 P G S + P P +P PG G P P PGP+ Sbjct: 1194 PPGLPGLSGQKGDGGLPG----IPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPAL 1247 Query: 3705 QG-SGSP-------RPGTKTGGGSQPQPASGQLQSETATTPAKPSFP--------SRSPA 3748 +G G+P RPG G P +G ++ E P +P P P Sbjct: 1248 EGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKG-NPGQPGLPGLPGLKGDQGPPG 1306 Query: 3749 PERLPARAQAKSCTKGPREAGEQGPHGSLGPK-EKGESSTKRKKGQV--------PGPA- 3798 + P R P G G G GP G + + + G + PGP+ Sbjct: 1307 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1366 Query: 3799 RSESVGSFGRAPSAPDKP--PRTPRKQATPSRVLPTKP--KPNSQNKPRPPPSEQRKAEP 3854 +S + P P +P P Q PT P P P + RK +P Sbjct: 1367 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1426 Query: 3855 GHTQRKDRLGKAFPQGRPLLR----PPKRGTAVHG 3885 G + G P G L+ PP + HG Sbjct: 1427 GLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHG 1461 Score = 47.8 bits (112), Expect = 2e-04 Identities = 113/463 (24%), Positives = 147/463 (31%), Gaps = 74/463 (15%) Query: 3432 GQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPST 3491 G K E P +PG PGP E P PRG + +P P Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGF-PGP-EGPPGPRGQK---GDDGIPGPPGPKGIRGPPG 96 Query: 3492 TKGWPETLERPV------DPVTHPIRGCELPSNHQECPP----PSLS--PFPAALADGRG 3539 G+P T P P I GC + P P L P P + +G Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-------------RPGARGQDAEGK 3586 + P + +PG PGP Q LP +P PG G Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 3587 RAPLVFSGKRRAPGARGRCAP-----DHFQEDHLLQKEKEVSSSHMVSEGGPRG-TFHKG 3640 L F G + G +G P ++ + E + + + GP G +G Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 3641 SATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA-----PGELARGTENGMKPAT 3695 P G + ++ K K + + + L PGE R E G K T Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT 336 Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755 PGP G PRPGT G + L E + FP P LP Sbjct: 337 --GPPGP--PGLVIPRPGTGITIGEKGNIGLPGLPGE----KGERGFPG-IQGPPGLP-- 385 Query: 3756 AQAKSCTKGPREAGEQGPHGSLG-PKEKGESSTKRKKG-QVPGPARSESVGSFGRAPSAP 3813 GP A GP G G P E+G+ + G +PGP + P AP Sbjct: 386 --------GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG------QPGAP 431 Query: 3814 DKP-PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 P P P P +P P P PP S K G Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGP-----PGPPGSPGDKGLQG 469 Score = 47.8 bits (112), Expect = 2e-04 Identities = 114/477 (23%), Positives = 150/477 (31%), Gaps = 62/477 (12%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS-EGSLPALLHLCSE 3486 PG+PG +A P + + M G PG P R P L + L L Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 3487 VAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546 +KG P L P P+ + G + E P L P ++ +G L G Sbjct: 937 TGEKGSKGEPG-LPGPPGPMDPNLLGSK-----GEKGEPGLPGIPG-VSGPKGYQGLPGD 989 Query: 3547 LERPENEASPGSPGPLLQQALPLGASLPR----PGARG----------QDAEGKRAPLVF 3592 +P PG PGP + P P PG +G Q EG P Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 3593 SGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSS 3652 G+ +PG G+ + + +SS + GP+G G + S Sbjct: 1050 PGQPGSPGLPGQKGD---------KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV 1100 Query: 3653 KDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP 3712 D P A G PG G P PK GP P Sbjct: 1101 GDPGLPGLPGTP--------GAKGQ--PG--LPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148 Query: 3713 GTKTGGGSQPQPA----SGQLQSETATTPA----KPSFPS-RSPAPERLPARAQAKSCTK 3763 G GGG QP G+ + PA +P P +P P LP + K Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208 Query: 3764 GPREAGEQGPHGSLG-PKEKGESSTKRKKGQ--VPGPARSESVGSFGRAPSAPDKPPRTP 3820 P G G G G P G + G PGPA G+ G P P P P Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG--PQGPPGRPGLP 1266 Query: 3821 RKQATP-----SRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 + P + K P P P + + PG R G +G P Sbjct: 1267 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDP 1323 Score = 44.7 bits (104), Expect = 0.002 Identities = 115/475 (24%), Positives = 140/475 (29%), Gaps = 62/475 (13%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG PG + LP PG GE PP P L L + Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN-----------PGLPGLPGNI 617 Query: 3488 APSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546 P G+ P PV I+G P P P G+ L G Sbjct: 618 GPMGPPGF-----GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP--GLPGN 670 Query: 3547 LERPENEASPGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF---SGKRRAPGAR 3602 R + PG PG Q LP + S PG G G P F G APG Sbjct: 671 PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730 Query: 3603 GRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS 3662 GR + K + GP G A P G DR P Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPG 784 Query: 3663 ----------KALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP 3712 K V P G + P L G P P PGP Q P Sbjct: 785 PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG--PPGPPGIPGPIGQPGLHGIP 842 Query: 3713 GTKTGGGSQPQPASGQL-QSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ 3771 G K G G + + P P P P LP +A A E G Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMM 901 Query: 3772 GPHGSLGPKE----------KGESSTKRKKGQVPGPARSESVGSFGR----APSAPDKPP 3817 GP G GP KG+ + + G +PGP + GS G P P P Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEK--GSKGEPGLPGPPGPMDPN 958 Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 K LP P + + P + +PG + + G P+G P Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLPGPPGPKGNP 1011 Score = 43.1 bits (100), Expect = 0.005 Identities = 205/900 (22%), Positives = 270/900 (30%), Gaps = 129/900 (14%) Query: 1684 GDSRPPQD-VCLPEPSKQPGPQLDAGSLAK---CSPDQELSFPKNKEAASSQESEDSLRL 1739 G PP D +C P P PG D G + + F S + L Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500 Query: 1740 LPCEQRGGFLPEPG-TADQPHRGAPAPEAFGSPAVHLAPDL-AFQGDGAPPLDATWPFGA 1797 LP G L PG ++ GA P+ G P + AP F G P D F Sbjct: 501 LPGPP--GSLGFPGQKGEKGQAGATGPK--GLPGIPGAPGAPGFPGSKGEPGDIL-TFPG 555 Query: 1798 SPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLV------PVP 1851 + S G G G PG G + G L P+G + P Sbjct: 556 MKGDKGELGSPGAPG-----LPGLPGTPGQD----GLPGLPGPKGEPGGITFKGERGPPG 606 Query: 1852 SPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGL--QELTPAAQSPP---- 1905 +P P + PP PGP K G+ G Q P + P Sbjct: 607 NPGL-----PGLPGNIGPMGPP--GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659 Query: 1906 -RVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQ----LGLEA-DGHWGLLG 1959 + GL G G V G PG + +P G +GL G G G Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719 Query: 1960 QAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMS 2019 GT ++ E P G P AL GP L G + A+ Sbjct: 720 IPGPPGAPGTPGRIGLE---GPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGALG 772 Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSV 2079 + + P PP P + L G G+ P PGL P + P P Sbjct: 773 PKGD-RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGL--PGIGVQGPPGPP- 827 Query: 2080 GDLAACAPSPTSAAH-MPCSLG-PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137 P H +P G P P + P +G G +P +P PPG Sbjct: 828 ---GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG--IPGAPGPIGPPG---- 878 Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCL----LQGE--- 2190 SP A G T P PP P + + G LQG+ Sbjct: 879 ---SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP--GRSGVPGLKGDDGLQGQPGL 933 Query: 2191 -------GSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243 GS E PPG + G+ + IP S + PG P Sbjct: 934 PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993 Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPG-------PDPQSRGAPPHTNPDRMPR 2296 L+G G P GL G P PQ PP P +P Sbjct: 994 GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP--GPSGVP- 1050 Query: 2297 GHSSYSPSNTARLGHREGQAVTAV-------PTEPPTLQGAGPDSPACLEGEMGTSSKEP 2349 SP + G + ++++ P P L G P +P ++G +G P Sbjct: 1051 -GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY-PGNPG-IKGSVGDPGL-P 1106 Query: 2350 EDPGTP-ETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQG 2408 PGTP G+ G P P G+ + P + + + P G Sbjct: 1107 GLPGTPGAKGQPGLPGFPGTPGPPGPKGI--SGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 2409 DPLGP-QDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKH 2467 + P QD G K +P G P G PGLS K Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFG---NPGPPGL-------------PGLSGQKGDGG 1208 Query: 2468 RPH-PGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPP 2526 P PG P P P P + PP + G + +G P P P Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGP 1268 Score = 40.4 bits (93), Expect = 0.035 Identities = 56/209 (26%), Positives = 69/209 (33%), Gaps = 18/209 (8%) Query: 3693 PATPKAKPGPSSQGSG---SPRPGTKTGGGSQPQPASGQLQSETATT----PAKPSFPSR 3745 P P PG + S PG K G P L T P P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 3746 SPAPERLPA-RAQAKSCTKGPR-EAGEQGPHGSLGP-----KEKGESSTKRKKGQ--VPG 3796 P P LP + +GP+ E GEQG G GP ++K + +KG +PG Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 3797 PARSESVGSFGRAPSAPDKPPRTPRKQATPS-RVLPTKPKPNSQ-NKPRPPPSEQRKAEP 3854 P P +Q P R P K N Q P P EP Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324 Query: 3855 GHTQRKDRLGKAFPQGRPLLRPPKRGTAV 3883 G K + G P G P L P+ GT + Sbjct: 325 GRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353 Score = 37.7 bits (86), Expect = 0.23 Identities = 50/197 (25%), Positives = 62/197 (31%), Gaps = 35/197 (17%) Query: 489 PTARPSPHGMEMLSRLPFPAG-----GPEWQGGSQGALGTAGK-----TPGPREKLPAVR 538 P P P G + +P P G GP G G G G PGP + +P Sbjct: 67 PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP-QGIPGCN 125 Query: 539 SSQG-----GSPALFTYNGMTDPGAQPLFFG-----VAQPQVSPHGTPSLPPPRVVGASP 588 ++G GSP G P P G + P G P P P + P Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP 185 Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSA--FFHPPTHPQETGS 646 + +P P P P P LPGP G F P E G Sbjct: 186 GPTGIPGPIGPPG-------PPGLMGPPGPPG----LPGPKGNMGLNFQGPKGEKGEQGL 234 Query: 647 PFPSPEPPHSLPTHYQP 663 P P PP + +P Sbjct: 235 QGP-PGPPGQISEQKRP 250 Score = 37.0 bits (84), Expect = 0.39 Identities = 169/712 (23%), Positives = 217/712 (30%), Gaps = 136/712 (19%) Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASA 3265 P P+ G R G PG P + PG P P + DGA P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH-DGAPGPQGIPG 123 Query: 3266 T--ALADAGSPGPP-----RTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCG--- 3315 + G PG P + P P P GEP + + + P + + G Sbjct: 124 CNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKGNPGYPGPPG 180 Query: 3316 -KRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLY 3374 + P P + + P + P P + G + + G G LQ P Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240 Query: 3375 ACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGAP--G 3432 ++ I + F K +Q L G R P G+R P P G Sbjct: 241 PGQISEQKRPI----------DVEFQKGDQ-------GLPGDRGPPGPPGIRGPPGPPGG 283 Query: 3433 QKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTT 3492 +K E P KR + PG+D E P + Sbjct: 284 EKGEKGEQGEPGKRGK---------PGKD-----------GENGQPGI------------ 311 Query: 3493 KGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA--LADGRGDCALDGAL--- 3547 G P P +P +G + PP + P P +G+ L G Sbjct: 312 PGLPGDPGYPGEPGRDGEKG-QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370 Query: 3548 -ER--PENEASPGSPGPLLQQALPLGASLPR--PGARGQDAEGKRAPLVFS-----GKRR 3597 ER P + PG PGP A +G P PG RGQ +G P S G Sbjct: 371 GERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQ--KGDEGPPGISIPGPPGLDG 426 Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR-- 3655 PGA G P H + S + E GP G G Q D+ Sbjct: 427 QPGAPGLPGPPGPAGPH-------IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479 Query: 3656 -------SAASTPSKALKFPVHPRKAVGSLA----PGELARGTENGMK--PATPKAKPGP 3702 + S P P P GSL GE + G K P P A P Sbjct: 480 TCFNCIGTGISGPPGQPGLPGLPGPP-GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538 Query: 3703 SSQGS-GSPR-----PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756 GS G P PG K G P + L T P + P P P+ P Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGL-PGPKGEPGGI 596 Query: 3757 QAKSCTKGPR----------EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSF 3806 K +GP G GP G P GE + G P G Sbjct: 597 TFKG-ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655 Query: 3807 GRAPSAPDKP--PRTPRKQATPSRVLPTKP-KPNSQNKPRPPPSEQRKAEPG 3855 G+ + P KP P P + LP P P P P S K EPG Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVG--LPGDPGLPGQPGLPGIPGS---KGEPG 702 Score = 34.3 bits (77), Expect = 2.5 Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 16/133 (12%) Query: 3183 LGDLPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240 L LPG G +G + + P PK G G PG G + PG Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 3241 ERAKPRARSTPS--------NPDGAATPDSASATALA----DAGSPGPPRT--TPSPSPD 3286 E+ KP P G P L+ D G PG P P P + Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224 Query: 3287 PWAGGEPLLQATP 3299 P G P +Q P Sbjct: 1225 PGFHGFPGVQGPP 1237 Score = 34.3 bits (77), Expect = 2.5 Identities = 73/312 (23%), Positives = 92/312 (29%), Gaps = 61/312 (19%) Query: 1623 QGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQA 1682 +G PG P +PG L + + G P P P K G Sbjct: 1181 KGEPGQ----PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL---PGPKGEPGFHGFPGV 1233 Query: 1683 EGDSRPPQDV--CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL 1740 +G PP L P PGPQ G P+ P N Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGN---------------- 1277 Query: 1741 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS 1800 GG E G QP G P G P + +GD PP G + Sbjct: 1278 -----GGIKGEKGNPGQP--GLP-----GLPGL--------KGDQGPP-------GLQGN 1310 Query: 1801 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860 G + + L G PG +G P+G P G E L+ P P + Sbjct: 1311 PGRPGLNGMKGDPGLPGVPGFPGMKG----PSGVPGSAGPEG-EPGLIGPPGPPGL---- 1361 Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920 P Q + +PG K G G Q L P +GL G GG Sbjct: 1362 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1421 Query: 1921 KVACGPAQGSPG 1932 + G PG Sbjct: 1422 RKGDPGLPGQPG 1433 Score = 33.9 bits (76), Expect = 3.3 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 16/121 (13%) Query: 3186 LPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAKKDS 3238 LPG GL G + + + P P+ G G PG P G +G+ S Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072 Query: 3239 PGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQAT 3298 G P + P P P ++ D G PG P T P A G+P L Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKG--SVGDPGLPGLPGT-------PGAKGQPGLPGF 1123 Query: 3299 P 3299 P Sbjct: 1124 P 1124 Score = 33.1 bits (74), Expect = 5.6 Identities = 22/55 (40%), Positives = 22/55 (40%), Gaps = 3/55 (5%) Query: 1232 PGLLIPEQPPPSRH---DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283 PG PE PP R D G P P G P G PG L G PG AP Sbjct: 62 PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 102 bits (255), Expect = 6e-21 Identities = 353/1470 (24%), Positives = 442/1470 (30%), Gaps = 295/1470 (20%) Query: 4 ERPRGAPPPTMTGDLQPRQVASSPGHPSQ-----PPLEDNTPATRTTKGAREAGGQAQAM 58 E P+G PP GD PG P PP P G G Sbjct: 69 EGPQG--PPGQKGD------TGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPP 120 Query: 59 ELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQA-PSRLAGRAEGSPP 117 +P + G L PP L PG G+P PPG ++ P + G G Sbjct: 121 GIPGCNGTKGERGPLGPPGL--------PGFAGNP-GPPGLPGMKGDPGEILGHVPG--- 168 Query: 118 QRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPG--TGAPLRPGLPRTEAQPAA 175 + + R P + TP P LP + P GP TG P PG P P Sbjct: 169 ----MLLKGERGFPGIPGTPGPP-----GLPGLQGPVGPPGFTGPPGPPGPP----GPPG 215 Query: 176 EELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSW 235 E+ FQ P + P P PG Q + + G + G Sbjct: 216 EKGQMGLSFQGPKGDKGDQGVSGP-----PGVPGQAQVQ-----EKGDFATKGEKGQKGE 265 Query: 236 PPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFP-FPALHGASTKPFPADVAG 294 P PG P +P P K + G S FP P G + P G Sbjct: 266 P--GFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKG 323 Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVGTGP-------AYPLPT----QPAPSPLPCYQGQPG 343 A GP P +GTGP YP +P P P GQPG Sbjct: 324 EAGPPGP------------PGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPG 371 Query: 344 --GLNRHSDLSGALSSPG-AAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSS 400 GL +GA PG R F + LP PS +DGL G P Sbjct: 372 PPGLPVPGQ-AGAPGFPGERGEKGDRGFPGT-------SLP--GPSGRDGLPGPPGSPGP 421 Query: 401 LPQRHFPGQAYRASG-VDTSPGPPDTELAAPGPP--PARLPQLWDP----------TAAP 447 PGQ +G V+ PGPP + PG P P + ++ + Sbjct: 422 ------PGQPGYTNGIVECQPGPPGDQ-GPPGIPGQPGFIGEIGEKGQKGESCLICDIDG 474 Query: 448 YPTPPGGPLAATRSMFFNGQPSPGQRLCLPQS---APLPWPQVL------PTARPSPHGM 498 Y PP GP + F GQP LP A +P PQ P A+ P Sbjct: 475 YRGPP-GPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEF 533 Query: 499 EMLSRLPFPAGGPEWQG--GSQGALGTAGK-----TPGPREKLPAVRSSQGGSPALFTYN 551 RL G P + G G G G+ G+ PGP+ GSP Sbjct: 534 YFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPK-----------GSPGSVGLK 582 Query: 552 GMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVG--------ASPSESPLPSPATNTAGS 603 G P F G ++ P G P P +G P LP P Sbjct: 583 GERGPPGGVGFPG-SRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEP--- 638 Query: 604 TCSSLSPMSSSPANPSSEESQ-LPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQ 662 + P+ P S PGP G F P P G +P P Sbjct: 639 --GKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPG 696 Query: 663 PEPAKAFPFPADGLGAEG--AFQCLEETP---FPHEGPEVGRGGLQGFPRAP--PPYPTH 715 P+ P G G F L P P VG GL+G P P P P Sbjct: 697 PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756 Query: 716 HFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPS 775 S+ + G + G + PGPPGLP Sbjct: 757 KGSIGVPGVPGEH-------------------------GAIGPPGLQGIRGEPGPPGLPG 791 Query: 776 PPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPL----RTGFLPSLAATPFPLPASD 831 +P VP G G G P GF P P P D Sbjct: 792 SVGSPGVPGIGPPGARGP------PGGQGPPGLSGPPGIKGEKGF-PGFPGLDMPGPKGD 844 Query: 832 LDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGV 891 + L G+ QS P + P P P S K + GV Sbjct: 845 KG-----------AQGLPGITGQSGLPGLPGQ------QGAPGIPGFPGS----KGEMGV 883 Query: 892 TPESKAPPPLPAATPDPQTP-RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQ 950 + P P P P GD G P P+ G + D G + G Sbjct: 884 M-GTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPR----GDPGLKGDKGDVGLPGKPGSM 938 Query: 951 LKLFRKDLDSGGAAEG-SGSGGGGRASGLRPRRND-GLGERPPPRPRRPRTQAPGSRADP 1008 K+ D+ S +G G G G + R D G P + + PG + DP Sbjct: 939 DKV---DMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDP 995 Query: 1009 A-PRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFA 1067 P A LP S LP + G G + D Sbjct: 996 GISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGL-----------PGDKG 1044 Query: 1068 SESEEDEQPPP--RGPGFRGRRG----------RGEKRKEVELTQGPREDEPQKPRKAAR 1115 ++ E+ + PP PG RG +G GEK ++ + P K + Sbjct: 1045 AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP--GLKGSP 1102 Query: 1116 QEAGGDGAPANPEEPGG-SRPG----PGRSPQARGPSRSLETGAAAREGGPKCADRPSVA 1170 G G+P P E G PG PG +A P TG A ++G P P A Sbjct: 1103 GSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSA 1162 Query: 1171 PKDPLQVPTNTETSEETRPSLDFP------------QEAKEPETAEESAPDSTEFTEALR 1218 E E P FP E P A ++ + Sbjct: 1163 ----------GEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFM 1212 Query: 1219 SPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGG 1276 PP G+ G SPG E P R G P G P G GV G Sbjct: 1213 GPPGP-QGQPGLPGSPG-HATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGN 1270 Query: 1277 PGGTQAPVSHNSKDPPARQ--PGEFLAPVANPSSTACPKPSV--LSSKISSFGCDPAGFN 1332 PG AP K P Q PG +P S P V G + Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330 Query: 1333 RDPLGVPVAKKGPQPYSSPHSELFLGPKDL 1362 + GVP AK P P P GP D+ Sbjct: 1331 QGDQGVPGAKGLPGPPGPP------GPYDI 1354 Score = 83.6 bits (205), Expect = 4e-15 Identities = 327/1407 (23%), Positives = 440/1407 (31%), Gaps = 280/1407 (19%) Query: 2 PGERPR-GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTP-ATRTTKGAREAGGQAQAME 59 PGE+ + G GD + V+ PG P Q +++ AT+ KG + G Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGF----- 268 Query: 60 LPEAQPRQARDGELKPPSLRGQ-APSSTPGKRGSPQTP-----PGRSPLQAPSRLAGRAE 113 + P GE P RG+ G++GSP P PG Q P G A Sbjct: 269 --QGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAG 326 Query: 114 GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQG-PGT----GAPLRPGLPR 168 P ++G T P L E E P P+G PG G P +PG P Sbjct: 327 PPGPPGIVIG-----TGP-LGEKGERGY------PGTPGPRGEPGPKGFPGLPGQPGPPG 374 Query: 169 TEAQPAAEELGFH-RCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEY 227 A GF ++ F T+ PS R PGPP S G Sbjct: 375 LPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSG--RDGLPGPPGSPG------------ 420 Query: 228 QASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287 PP PG G+ +P P P P G P F Sbjct: 421 --------PPGQ----PGYTNGIVECQPGP-PGDQGPPGIPGQPGFIGEIGEKGQKGESC 467 Query: 288 FPADVAGHAFTNGPLVFAFHQPQG--AWPEEAVGTGPAYPLPTQ------PAPSPLPCYQ 339 D+ G+ GP P G +P + G LP + P P P Sbjct: 468 LICDIDGYRGPPGP-----QGPPGEIGFPGQPGAKGDR-GLPGRDGVAGVPGPQGTPGLI 521 Query: 340 GQPGGLNRHSDL------------SGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSA 387 GQPG + G PG A P D H L P+ P + Sbjct: 522 GQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDG-HPGLPG--PKGSPGS 578 Query: 388 QDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP 447 GL RGPP + FPG + G PGPP A P + D A Sbjct: 579 V-GLKGERGPPGGVG---FPG----SRGDTGPPGPPGYGPAGP---------IGDKGQAG 621 Query: 448 YPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLP-F 506 +P PG P G P P + P +++P P P G E L P F Sbjct: 622 FPGGPGSP----------GLPGP-------KGEP---GKIVPL--PGPPGAEGLPGSPGF 659 Query: 507 PAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFG 564 P GP+ G +G GT G+ P EK + G G P +G+ PG Sbjct: 660 P--GPQ---GDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGL--PG------- 705 Query: 565 VAQPQVSPHGTPSLPPPRVVGASPS-ESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623 + P GTP P + +P + P G L + P P + S Sbjct: 706 ----DMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPG--LKGLPGLPGIPGTPGEKGS 759 Query: 624 -QLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAF 682 +PG G PP G P P P P S+ + P G+G GA Sbjct: 760 IGVPGVPGEHGAIGPPGLQGIRGEPGP-PGLPGSVGSPGVP-----------GIGPPGA- 806 Query: 683 QCLEETPFPHEGPEVGRG--GLQGFP-----RAPPPYPTHHFSLSSASLDQLDVLLTCRQ 735 GP G+G GL G P + P +P + D+ L Sbjct: 807 ----------RGPPGGQGPPGLSGPPGIKGEKGFPGFPG--LDMPGPKGDKGAQGLPGIT 854 Query: 736 CDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAK 795 L G ++ + G +PG PG P P AP +P + H Sbjct: 855 GQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKG----DHG- 909 Query: 796 TFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDME-------DDAKLDSLITEAL 848 G + G DP G + P +DM D + + Sbjct: 910 ---FPGSSGPRG--DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGE 964 Query: 849 NGMEYQSDNPEIDSSFIDVFADEEPSGPRG----------PSSGHPLKSKAGV----TPE 894 G P + +P GP+G P P S G+ TP Sbjct: 965 KGSRGDPGTPGVPGKDGQAGQPGQP-GPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPG 1023 Query: 895 SKAPPPLPAATPDPQTPRPGDRGCPAR----GRPKTRSLGLAPTEAD---APSQGRQQRR 947 K P +P P P GD+G G P GL + D A G + Sbjct: 1024 EKGVPGIPGPQGSPGLP--GDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEK 1081 Query: 948 GKQLKLFRKDLDSGGAAEGS-GSGGGGRASGLRPRRND----GLGERPPPRPRRPRTQAP 1002 G++ + + +GS GS G + GL + D GL P + P Sbjct: 1082 GEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP 1141 Query: 1003 GSRADPAPR-VPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061 G + P + +P LP R P A+G K Sbjct: 1142 GPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKG-------------DKGSK 1188 Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR----GEKRKEVELTQGPREDEPQKPRKAARQ 1116 E F + P +G GF G G G T+GP+ D + + Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPG 1248 Query: 1117 EAGGDGAPANPEEPG--GSRPGPG--RSPQARGPSRSLETGAAAREGGPKCADRPSVAPK 1172 G G P P G G + PG +P GP G +G P P + Sbjct: 1249 LPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPK-----GDPGFQGMPGIGGSPGITGS 1303 Query: 1173 DPLQVPTNTETSEETR--PSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGE--M 1228 P + + P L + + + ++ P + + L PP + Sbjct: 1304 KGDMGPPGVPGFQGPKGLPGL----QGIKGDQGDQGVPGA----KGLPGPPGPPGPYDII 1355 Query: 1229 GASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLG--------GPGGT 1280 PGL PE PP + G P P G T G PG+ G GP G Sbjct: 1356 KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGP 1415 Query: 1281 QAPVSHNSKDPPARQPGEFLAPVANPS 1307 P P PG + P PS Sbjct: 1416 TGPRGFPGPPGPDGLPGS-MGPPGTPS 1441 Score = 56.2 bits (134), Expect = 6e-07 Identities = 117/468 (25%), Positives = 156/468 (33%), Gaps = 77/468 (16%) Query: 3392 CSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRP----GAPGQKARALEGTLPSKRR 3447 C C+ K ++ +R L G + F G++ P G PGQK E LP + Sbjct: 36 CGKCDCHGVKGQKGERG----LPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKG 91 Query: 3448 RVAMPGSA--PG-------PGEDRPP-PRGSSPILSEGSLPALLHLCSEVAPSTTKGWPE 3497 PG++ PG PG+D PP P G +P E P G P Sbjct: 92 TRGPPGASGYPGNPGLPGIPGQDGPPGPPG---------IPGCNGTKGERGPLGPPGLPG 142 Query: 3498 TLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPG 3557 P P ++G P L P L +G+ G P PG Sbjct: 143 FAGNPGPPGLPGMKG---------DPGEILGHVPGMLL--KGERGFPGIPGTPGPPGLPG 191 Query: 3558 SPGPLLQQALPLGASLP--RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHL 3615 GP+ P G + P PG G E + L F G + G +G P Sbjct: 192 LQGPV----GPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQ 247 Query: 3616 LQKEKEVSSSHMVSEGGP------RGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPV 3669 +Q++ + ++ + G G KG KP KD S FP Sbjct: 248 VQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPG--FPG 305 Query: 3670 HPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQL 3729 P PG + R G K PGP G+ G K G + P + Sbjct: 306 EPG------YPGLIGRQGPQGEKGEA--GPPGPPGIVIGTGPLGEK---GERGYPGTPGP 354 Query: 3730 QSETATTPAKPSFPS--RSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESST 3787 + E P FP P P LP QA P E GE+G G G G S Sbjct: 355 RGE----PGPKGFPGLPGQPGPPGLPVPGQA-GAPGFPGERGEKGDRGFPGTSLPGPSG- 408 Query: 3788 KRKKGQVPGPARSES-VGSFGRAPSAPDKPPRTPRKQATPSRVLPTKP 3834 + +PGP S G G + P P Q P +P +P Sbjct: 409 ---RDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPG--IPGQP 451 Score = 51.2 bits (121), Expect = 2e-05 Identities = 211/963 (21%), Positives = 292/963 (30%), Gaps = 229/963 (23%) Query: 1684 GDSRPPQDVCLPEPSKQPGPQLDAG-----SLAKCSPDQELSFPKNKEAASSQESED--S 1736 G PP ++ P QPG + D G +A Q + A + E Sbjct: 480 GPQGPPGEIGFPG---QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFD 536 Query: 1737 LRLLPCEQRGGFLPEPGTADQP-------HRGAPAPEAFGSPAVHLAPDLAFQGDGAPPL 1789 LRL + GF +PG + H G P P+ GSP + +G+ PP Sbjct: 537 LRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPK--GSPG-----SVGLKGERGPPG 589 Query: 1790 DATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASS--LTAPRGREAWL 1847 +P ++G + G G + AG G +G P G S L P+G + Sbjct: 590 GVGFP-------GSRGDT-GPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKI 641 Query: 1848 VPVPSPACVSNT--------------------HPSRRSQDPALSPPIRQLQLPGPGVAKS 1887 VP+P P P + A+ P + PGP K Sbjct: 642 VPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQP--GIGFPGPPGPKG 699 Query: 1888 KDGILGLQELTPAAQSPPRVNPSGLEGGT-VEGGKVACGPA-------------QGSPGG 1933 DG+ G ++ P +P R +GL G V+G K G G+PG Sbjct: 700 VDGLPG--DMGPPG-TPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756 Query: 1934 VQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNAS 1993 +P V G + G G+ G+ G+ G+ P G Sbjct: 757 KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGS-PGVPGIGPPGARGPPGGQGP 815 Query: 1994 PKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEG 2053 P L+GP KG + P P P + A L +SG G Sbjct: 816 P--GLSGP-------PGIKGEKGFPGF-----PGLDMPGPKGDKGAQGLPGITGQSGLPG 861 Query: 2054 RTPERASSPGL--------NKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPRE 2105 P + +PG+ ++ T P +P P A +P G Sbjct: 862 -LPGQQGAPGIPGFPGSKGEMGVMGTPGQPG---------SPGPVGAPGLPGEKG--DHG 909 Query: 2106 DPLTSPSRAQGGLGGQ-----LPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG 2160 P +S R GL G LP P D + G + Sbjct: 910 FPGSSGPRGDPGLKGDKGDVGLPGKPGSMDK-------------VDMGSMKGQKGDQGEK 956 Query: 2161 AEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDS 2220 + P+ P P G P +D + PG PK Sbjct: 957 GQIGPIGEKGSRGDPGTP------------GVPGKDGQAGQPGQPG----------PKG- 993 Query: 2221 TLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPG-PD 2279 PG + +P G P +V GL TP +G+PG P Sbjct: 994 ---------------DPGISGTPGAPGLPGPKGSVGGMGLPGTP------GEKGVPGIPG 1032 Query: 2280 PQSRGAPPHTNPDRMPRGHSSYSPSNTARL-GHREGQAVTAVPTEPPTLQGAG------- 2331 PQ P + +G + L G + Q + P P G Sbjct: 1033 PQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGM 1092 Query: 2332 PDSPACLEGEMGTSSKEPEDPGTP-ETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDF 2390 P SP L+G G S P PG P E G G + + GL T P+ A Sbjct: 1093 PGSPG-LKGSPG-SVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAG-- 1148 Query: 2391 QSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCA 2450 Q P S +G+P P RG+ P + + KG EV Sbjct: 1149 QKGEPGSDGIPGSAGEKGEPGLP------GRGFPGFPGAKGDKGSKG---------EVGF 1193 Query: 2451 ASFRSGPGLSRHKARK-------HRPHPGAPAEPSPAAL-------PAQQP-LEPLAQKC 2495 PG+ K + + PG P P A P QP L L Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPM 1253 Query: 2496 QPP----------RKKSHRVSGKERPNHSRGDPSHVTQP-----PPAQGSKEVLRAPGSP 2540 PP K + G +GDP P P GSK + PG P Sbjct: 1254 GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVP 1313 Query: 2541 HSQ 2543 Q Sbjct: 1314 GFQ 1316 Score = 47.4 bits (111), Expect = 3e-04 Identities = 115/483 (23%), Positives = 150/483 (31%), Gaps = 70/483 (14%) Query: 3413 LRGGRQP---FAFRGVRRP-GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGS 3468 L+G R P F G R G PG G + K + PG PG P P+G Sbjct: 581 LKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQ-AGFPGGPGSPG--LPGPKGE 637 Query: 3469 S----PILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPP 3524 P+ L P +G+P T RP LP Sbjct: 638 PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRP-----------GLPGEKGAVGQ 686 Query: 3525 PSLS----PFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLP----RP 3576 P + P P + GD G RP PG+PG Q+ P G LP P Sbjct: 687 PGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEP-GVGLPGLKGLP 745 Query: 3577 GARG-QDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRG 3635 G G G++ + G PG G P Q + + V G G Sbjct: 746 GLPGIPGTPGEKGSIGVPG---VPGEHGAIGPPGLQ--GIRGEPGPPGLPGSVGSPGVPG 800 Query: 3636 TFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT 3695 G+ P G K FP P G PG G+ Sbjct: 801 IGPPGARGPPGGQGPPGLSGPPGIKGEKG--FPGFP----GLDMPGPKGDKGAQGL---- 850 Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755 PG + Q PG + G P S + + TP +P SP P P Sbjct: 851 ----PGITGQSGLPGLPGQQGAPGIPGFPGS-KGEMGVMGTPGQPG----SPGPVGAPGL 901 Query: 3756 AQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDK 3815 P E G+ G GS GP +G+ K KG V P + S+ K Sbjct: 902 ---------PGEKGDHGFPGSSGP--RGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQK 950 Query: 3816 PPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLR 3875 + + Q P + K P P + + +PG K G + G P L Sbjct: 951 GDQGEKGQIGP---IGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLP 1007 Query: 3876 PPK 3878 PK Sbjct: 1008 GPK 1010 Score = 46.6 bits (109), Expect = 5e-04 Identities = 304/1293 (23%), Positives = 398/1293 (30%), Gaps = 274/1293 (21%) Query: 1678 GLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKC-------SPDQELSFPKNKEA-AS 1729 GL +G PP P P PGP + G + DQ +S P A Sbjct: 188 GLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQ 247 Query: 1730 SQESEDSLRLLPCEQRG--GFLPEPGTADQPHRGAPAPEA----------FGSPAVHLAP 1777 QE D Q+G GF PG ++ G P P GSP P Sbjct: 248 VQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEP 307 Query: 1778 DL----------AFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGN 1827 +G+ PP G P G G +P G PG G Sbjct: 308 GYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGP--------LGEKGERGYP--GTPGPRG- 356 Query: 1828 EFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQ-------DPALSPPIRQLQLP 1880 E P G L G +PVP A P R + +L P + LP Sbjct: 357 EPGPKGFPGLPGQPGPPG--LPVPGQAGAPG-FPGERGEKGDRGFPGTSLPGPSGRDGLP 413 Query: 1881 G-------PGVAKSKDGILGLQELTPAAQSPP----------RVNPSGLEGGT-----VE 1918 G PG +GI+ Q P Q PP + G +G + ++ Sbjct: 414 GPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDID 473 Query: 1919 GGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEA----------DGHWGLLGQAEKTQGQG 1968 G + GP QG PG + P G + GL G GL+GQ G Sbjct: 474 GYRGPPGP-QGPPGEIGFPGQPGAKGDR-GLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531 Query: 1969 --------TANQLQPENGVSPGGTDNHASVNASPKTALTGP--TEGAVLLEKCKGSRAAM 2018 ++ P PG T S L GP + G+V L+ +G + Sbjct: 532 EFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGV 591 Query: 2019 SLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRT--PERASSPGLNKPLLATGDSPA 2076 T PP P A + G +G+ P SPGL P G Sbjct: 592 GFPGSRGDT-GPPGPPGYGPAGPI-------GDKGQAGFPGGPGSPGLPGPKGEPGK--- 640 Query: 2077 PSVGDLAACAPSPTSAAHMPCSLG-PLPREDPLTSPSRAQGGLGGQLPA----SPSCRDP 2131 P P A +P S G P P+ D + + GL G+ A P Sbjct: 641 ------IVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGP 694 Query: 2132 PGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAP--------PSLTTSPCDPKEALA 2183 PGP+ + DG+ D G +P P P + +P L Sbjct: 695 PGPKGV-------------DGLPG--DMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLP 739 Query: 2184 GCLLQG-------EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWES 2236 G L+G G+P E S PG V H P I + L S Sbjct: 740 G--LKGLPGLPGIPGTPGEKGSIGVPG----VPGEHGAIGP-PGLQGIRGEPGPPGLPGS 792 Query: 2237 PGRATSPPLA--GAVSPSVAVRATGLSSTP-----TGDEAQAGRGLPGP--DPQSRGAPP 2287 G P + GA P GLS P G G +PGP D ++G P Sbjct: 793 VGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG 852 Query: 2288 HTNPDRMP-RGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSS 2346 T +P +P G + V P +P + GP L GE G Sbjct: 853 ITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGS---PGPVGAPGLPGEKG--- 906 Query: 2347 KEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSD--SPQSHRNASHQ 2404 D G P G SG P + +GL P S + D S + + + Sbjct: 907 ----DHGFP--GSSGPRGDPGLKGDKGDVGL-----PGKPGSMDKVDMGSMKGQKGDQGE 955 Query: 2405 TPQGDPLGPQDLKQRSRGYKKKPA----STENGQWKGQAPHG-PVTCEVCAASFRSGP-- 2457 Q P+G ++ SRG P + GQ P G P A GP Sbjct: 956 KGQIGPIG----EKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKG 1011 Query: 2458 ---GLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHS 2514 G+ + PG P LP + + + PP + G++ Sbjct: 1012 SVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGI 1071 Query: 2515 RGDPSHVTQPPPAQGSKEVLRAPGSPHSQQL--------HPPSP--TEHEVDVKTPASKP 2564 G P P +G K + PG P S L +P SP + D P Sbjct: 1072 AGFPG----SPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDG 1127 Query: 2565 RPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVS 2624 P E L P + EP D S G+ + RG P Sbjct: 1128 IPGVKGEAGL-PGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRG--------FPGF 1178 Query: 2625 ADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQ----PPRLATLGPGVMEGAAE 2680 D +GS+ A SP G P + GEQ PP GP G Sbjct: 1179 PGAKGD-KGSKGEVGFPGLAGSP-------GIPGSKGEQGFMGPP-----GPQGQPGLPG 1225 Query: 2681 TDQEAL--CAGETGAQKPPGDRMLCPGRMDGAALG--EQPTGQKG----ASARGFWGPRE 2732 + A G+ G Q PG L PG M L + G KG A G GP+ Sbjct: 1226 SPGHATEGPKGDRGPQGQPGLPGL-PGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKG 1284 Query: 2733 TKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPP-----LGPLGFPETSSSPADSTTS 2787 G P S+ + PP GP G P D Sbjct: 1285 DPGFQGMPGIGGSPGITGSKG----------DMGPPGVPGFQGPKGLPGLQGIKGDQGDQ 1334 Query: 2788 SC--LQGLPDNPDTQG---------GVQGPEGP 2809 +GLP P G G+ GPEGP Sbjct: 1335 GVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP 1367 Score = 43.5 bits (101), Expect = 0.004 Identities = 123/511 (24%), Positives = 156/511 (30%), Gaps = 110/511 (21%) Query: 1068 SESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANP 1127 ++ E PP PGF G G + P E P + E G G P P Sbjct: 128 TKGERGPLGPPGLPGFAGNPGPPGLPG---MKGDPGEILGHVPGMLLKGERGFPGIPGTP 184 Query: 1128 EEPG-----GSRPGPGRSPQARGPSRSLETGAAAREG----GPKCADRPSVAPKDPLQVP 1178 PG G PG + P G + G GPK D+ P VP Sbjct: 185 GPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPK-GDKGDQGVSGPPGVP 243 Query: 1179 TNTETSEETRPSLDFPQEAKEPETAE---ESAPDSTEFTEALRSPPAACAGEMGAS---- 1231 + E+ DF + ++ + E + P E E + P G+ G Sbjct: 244 GQAQVQEKG----DFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKG 299 Query: 1232 ----------PGLLIPEQPPPSRHDTGTPKPSGSLANTAP---HGSSPTPGVGSLLGGPG 1278 PGL+ + P + + G P P G + T P G PG G PG Sbjct: 300 SPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPG 359 Query: 1279 GTQAPVSHNSKDPPARQ-PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLG 1337 P PP PG+ AP P K GF L Sbjct: 360 PKGFPGLPGQPGPPGLPVPGQAGAP---------GFPGERGEK------GDRGFPGTSLP 404 Query: 1338 VPVAKKG-PQPYSSPHSELFLGPKDLAGCF--LEELHPKPSARDAPPA------------ 1382 P + G P P SP GP G + E P P PP Sbjct: 405 GPSGRDGLPGPPGSP------GPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIG 458 Query: 1383 -----SSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFD 1437 SCL D + G P P+ PPG PG+ P DR Sbjct: 459 EKGQKGESCLICDID--GYRGPPGPQGPPGEIGF-PGQ-------------PGAKGDRGL 502 Query: 1438 PPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLS 1497 P G G P P K P + + L ++ P P P ++G Sbjct: 503 PGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQ-PGMTG----- 556 Query: 1498 KTCPPERTVVPG--AAPSLPG-KGSGCSVAL 1525 R PG P LPG KGS SV L Sbjct: 557 ------RAGSPGRDGHPGLPGPKGSPGSVGL 581 Score = 42.4 bits (98), Expect = 0.009 Identities = 73/293 (24%), Positives = 95/293 (32%), Gaps = 49/293 (16%) Query: 509 GGPEWQG--GSQGALGTAGKTPGPREKLPAVRSSQG--------GSPALFTYNGMTDPGA 558 G P QG G QG G G T P LP + ++G G+P L G P Sbjct: 61 GFPGMQGPEGPQGPPGQKGDTGEPG--LPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPG 118 Query: 559 QPLFFGV--AQPQVSPHGTPSLP-------PPRVVG--ASPSESPLPSPATNTAGSTCSS 607 P G + + P G P LP PP + G P E P G Sbjct: 119 PPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFP 178 Query: 608 LSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAK 667 P + P L GP+GP F PP P G P P E + P+ K Sbjct: 179 GIPGTPGPPGLPG----LQGPVGPPGFTGPPGPP---GPPGPPGEKGQMGLSFQGPKGDK 231 Query: 668 AFPFPADGLGAEGAFQCLEETPFPHEGP--EVGRGGLQGFP----RAPPPYPTHHFSLSS 721 + G G Q E+ F +G + G G QG P + P P Sbjct: 232 GDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPG- 290 Query: 722 ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLP 774 + D+ F + GL+ + G + GPPG P Sbjct: 291 ------------KDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPP 331 Score = 37.7 bits (86), Expect = 0.23 Identities = 85/349 (24%), Positives = 111/349 (31%), Gaps = 30/349 (8%) Query: 3531 PAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARGQDAEGKRAP 3589 P RGD G + PG PGP + P PG +G G P Sbjct: 961 PIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKG-SVGGMGLP 1019 Query: 3590 LVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649 G++ PG G D + EK + + G RG G Sbjct: 1020 GT-PGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSP 1078 Query: 3650 SSSKDRSAASTPSKALKFPVHP--RKAVGSLA-PGELARGTENGMKPATP-KAKPGPSSQ 3705 ++ + P P P + + GS+ PG E G K PG + Sbjct: 1079 GEKGEKGSIGIPG----MPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGE 1134 Query: 3706 GSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765 PG G + +P S + +A +P P R P AK Sbjct: 1135 AGLPGTPGPTGPAGQKGEPGSDGIPG-SAGEKGEPGLPGRG-----FPGFPGAKGDKGSK 1188 Query: 3766 REAGEQGPHGSLG-PKEKGESSTKRKKGQVPGPARSESV-GSFGRAPSAPDKPPRTPRKQ 3823 E G G GS G P KGE PGP + GS G A P K R P+ Q Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGP----PGPQGQPGLPGSPGHATEGP-KGDRGPQGQ 1243 Query: 3824 ATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 LP P P P P + K + G+ G P+G P Sbjct: 1244 PG----LPGLPGP--MGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDP 1286 Score = 37.0 bits (84), Expect = 0.39 Identities = 119/525 (22%), Positives = 156/525 (29%), Gaps = 119/525 (22%) Query: 3428 PGAPGQKA----RALEGT-LPSKRRRVAMPGSA-------------------PGPGEDRP 3463 PG PG++ R GT LP R +PG PGP D+ Sbjct: 384 PGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQG 443 Query: 3464 PPR--GSSPILSE-------GSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCE 3514 PP G + E G + + P +G P + P P RG Sbjct: 444 PPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLP 503 Query: 3515 LPSNHQECPPPSLSP----------------FPAALADGRGDCA------LDGALERPEN 3552 P P +P F L +GD + G P Sbjct: 504 GRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGR 563 Query: 3553 EASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQE 3612 + PG PGP PG+ G +G+R P G PG+RG P Sbjct: 564 DGHPGLPGP-----------KGSPGSVG--LKGERGP---PGGVGFPGSRGDTGP----- 602 Query: 3613 DHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPR 3672 GP G KG A P G S P K + P P Sbjct: 603 ----------PGPPGYGPAGPIG--DKGQAGFPGGPGSPGLP-GPKGEPGKIVPLPGPPG 649 Query: 3673 KAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSE 3732 +PG + G P TP +PG + +PG G P+ G L + Sbjct: 650 AEGLPGSPGFPGPQGDRGF-PGTP-GRPGLPGEKGAVGQPGIGFPGPPGPKGVDG-LPGD 706 Query: 3733 TAT--TPAKPSFPSRSPAP----------ERLPARAQAKSCTKGPREAGEQ--------- 3771 TP +P F P LP P GE+ Sbjct: 707 MGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVP 766 Query: 3772 GPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPP--RTPRKQATPSRV 3829 G HG++GP G + + G P S G G P PP + P + P + Sbjct: 767 GEHGAIGP--PGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGI 824 Query: 3830 LPTKPKPNSQNKPRPPPSEQRKAE--PGHTQRKDRLGKAFPQGRP 3872 K P P P + A+ PG T + G QG P Sbjct: 825 KGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAP 869 Score = 35.8 bits (81), Expect = 0.86 Identities = 46/186 (24%), Positives = 59/186 (31%), Gaps = 17/186 (9%) Query: 1237 PEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPG--GTQAPVSHNSKDPPAR 1294 P+ PP + DTG P G+ P G+S PG L G PG G P + Sbjct: 71 PQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKG 130 Query: 1295 QPGEFLAPVANPSSTACPKPSVLSSKISS----FGCDPAGFNRDPLGVPVAKKGPQPYSS 1350 + G L P P P P L G P + G P P P Sbjct: 131 ERGP-LGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGL 189 Query: 1351 PHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGE----DAGSLEPQLPRSPP 1406 P + +GP G P P PP + + D G P P Sbjct: 190 PGLQGPVGPPGFTG------PPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVP 243 Query: 1407 GTAETE 1412 G A+ + Sbjct: 244 GQAQVQ 249 Score = 33.5 bits (75), Expect = 4.3 Identities = 50/203 (24%), Positives = 67/203 (33%), Gaps = 36/203 (17%) Query: 3686 GTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFP-- 3743 GT+ P P PG + PG K G G L P P P Sbjct: 127 GTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGP 186 Query: 3744 ---------------SRSPAPERLPA----RAQAKSCTKGPREAGEQGPHGSLGP----- 3779 + P P P + Q +GP+ G++G G GP Sbjct: 187 PGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPK--GDKGDQGVSGPPGVPG 244 Query: 3780 ----KEKGESSTKRKKGQ--VPGPARSESVGSFGR--APSAPDKPPRTPRKQATPSRVLP 3831 +EKG+ +TK +KGQ PG VG G P KP + K S P Sbjct: 245 QAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFP 304 Query: 3832 TKPKPNSQNKPRPPPSEQRKAEP 3854 +P + P E+ +A P Sbjct: 305 GEPGYPGLIGRQGPQGEKGEAGP 327 Score = 32.3 bits (72), Expect = 9.5 Identities = 57/220 (25%), Positives = 73/220 (33%), Gaps = 45/220 (20%) Query: 2325 PTLQGA-GPDSPACLEGEMGTSSKEPEDPGTPET-GRSGATKMPRVTCPSTGLGLGRTTA 2382 P +QG GP P +G+ G EP PGT T G GA+ P G Sbjct: 63 PGMQGPEGPQGPPGQKGDTG----EPGLPGTKGTRGPPGASGYP-----------GNPGL 107 Query: 2383 PSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHG 2442 P D P + + PLGP L G+ P KG G Sbjct: 108 PGIPGQD-GPPGPPGIPGCNGTKGERGPLGPPGLP----GFAGNPGPPGLPGMKGDP--G 160 Query: 2443 PVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPA-QQPLEPLA--------Q 2493 + V PG+ + R PG P P P LP Q P+ P Sbjct: 161 EILGHV--------PGML---LKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPG 209 Query: 2494 KCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEV 2533 PP +K + P +GD V+ PP G +V Sbjct: 210 PPGPPGEKGQMGLSFQGPKGDKGDQG-VSGPPGVPGQAQV 248 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 102 bits (253), Expect = 1e-20 Identities = 312/1322 (23%), Positives = 413/1322 (31%), Gaps = 280/1322 (21%) Query: 28 GHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQ------ 81 G P P L P T T G + G LP + + G PP L G Sbjct: 337 GPPGPPGLVIPRPGTGITIGEK---GNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393 Query: 82 ---APSSTPGKRGSP--QTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDE- 135 P PG+RG + PPG S + P L G+ G+P G A P+ DE Sbjct: 394 GPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQP-GAPGLPGPPGPAGPHIPPS-DEI 450 Query: 136 ----------TPENPQLEAAQLPEVDTPQ------GPG-TGAPLRPGLPRTEAQPAAEEL 178 +P + L+ Q + D G G +G P +PGLP P + L Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS--L 508 Query: 179 GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPA 238 GF E + + P P APG P S+G +PG + D Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG----EPGDILTFPGMKGDK---- 560 Query: 239 AENSFPGANFGVP--PAEP--EPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAG 294 E PGA G+P P P + +P P G P G++F+ G P + G Sbjct: 561 GELGSPGAP-GLPGLPGTPGQDGLPGLPGPKGEPGGITFK-------GERGPPGNPGLPG 612 Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGA 354 GP+ P G P VG + P +P +G PG G Sbjct: 613 LPGNIGPM-----GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667 Query: 355 LSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRAS 414 +PG P L P +P G+ ++G P +P PG Sbjct: 668 PGNPGRDGDVGLPGDPGL--------PGQP--GLPGIPGSKGEPG-IPGIGLPGPP-GPK 715 Query: 415 GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPS-PGQR 473 G PGPP APG P R+ P +P P G P A G P PG + Sbjct: 716 GFPGIPGPP----GAPGTP-GRIGLEGPPGPPGFPGPKGEPGFALPGP--PGPPGLPGFK 768 Query: 474 LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAG--GPEWQGGSQGALGTAG----KT 527 L +P P P G L LP P G GP Q G G G G Sbjct: 769 GALGPKGDRGFP-----GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 528 PGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVG-- 585 PGP G+ P QP G+ + P G P L P G Sbjct: 824 PGPP--------------------GIPGPIGQPGLHGIPGEKGDP-GPPGLDVPGPPGER 862 Query: 586 ASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETG 645 SP P P + P S + S PG G PP P G Sbjct: 863 GSPGIPGAPGP-----------IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911 Query: 646 SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGF 705 P S P Q +P P P G++G L P P + +G G +G Sbjct: 912 IPGRSGVPGLKGDDGLQGQPG--LPGPTGEKGSKGE-PGLPGPPGPMDPNLLGSKGEKGE 968 Query: 706 PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQ 765 P P + + + GL + G Sbjct: 969 PGLP--------------------------------GIPGVSGPKGYQGLPGDPGQPGLS 996 Query: 766 RSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGD---AQAEGKDDPLRTGFLPSLAA 822 PG PG P P P +P GL+ GD +G + P +P Sbjct: 997 GQPGLPGPPGPKGNPGLP--GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054 Query: 823 TPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSG 882 +P LP D + D + S+ L G + + P + G +G S G Sbjct: 1055 SP-GLPGQKGD-KGDPGISSIGLPGLPGPKGEPGLPGYPGN----------PGIKG-SVG 1101 Query: 883 HPLKSKAGVTPESKAPPPLPA--ATPDPQTPR-----PGDRGCPARGRPKTRSLGLAPTE 935 P TP +K P LP TP P P+ PG+ G P G P G P + Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP--GEPGPVGGGGHPGQ 1159 Query: 936 ADAPSQ----------GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGL------- 978 P + G ++G+ + + G SG G G G+ Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219 Query: 979 RPRRNDGLG-----ERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPR 1033 P+ G + PP P P G + +P P+ P P + + LP Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGP-----PGRPGPTGFQGLPGP 1274 Query: 1034 KDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKR 1093 + P GG G E+ P PG G +G Sbjct: 1275 EGPPGLPGNGGIKG-----------------------EKGNPGQPGLPGLPGLKG----- 1306 Query: 1094 KEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETG 1153 QGP + R G G P P PG GP P + GP Sbjct: 1307 -----DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG--MKGPSGVPGSAGP------- 1352 Query: 1154 AAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEF 1213 EG P + P P +P + S + P +P P + Sbjct: 1353 ----EGEPGL-----IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1403 Query: 1214 TEALRSPPA----------ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHG 1263 PP AG PGL P Q P +R G P P G P G Sbjct: 1404 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL--PGQ-PGTRGLDGPPGPDGLQGPPGPPG 1460 Query: 1264 SS 1265 +S Sbjct: 1461 TS 1462 Score = 86.3 bits (212), Expect = 6e-16 Identities = 325/1384 (23%), Positives = 425/1384 (30%), Gaps = 260/1384 (18%) Query: 2 PGERPR----GAP-PPTMTGDLQPRQVASSPGHPSQP--PLEDNTPATRTTKGAREAGGQ 54 PG R + G P PP G P + PG P P P D P + G G+ Sbjct: 71 PGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130 Query: 55 AQAMELPEAQPRQARDGELKPPSLRGQAPS----STPGKRGSP--QTPPGRSPLQAPSRL 108 P Q G P ++G+ S S PG +G+P PPG L P+ + Sbjct: 131 RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGI 190 Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168 G P G+ P L N L Q P+ + + G P PG Sbjct: 191 PGPIGPPGPP----GLMGPPGPPGLPGPKGNMGLNF-QGPKGEKGEQGLQGPPGPPGQIS 245 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPA----PGPPQSRGTSPLQPGSY 224 + +P E F + Q P P PP PGPP + G Sbjct: 246 EQKRPIDVE--FQKGDQGLPGD---------RGPPGPPGIRGPPGPPGGEKGEKGEQGEP 294 Query: 225 PEYQASGADSWPPAAENSFPGANFGVP-----PAEP-------------EPIPKG---SR 263 + G D EN PG G+P P EP P P G R Sbjct: 295 GKRGKPGKDG-----ENGQPGIP-GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPR 348 Query: 264 PG-GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQG--AWPEEAVGT 320 PG G G P L G + + G GP A P G +P E Sbjct: 349 PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQK 408 Query: 321 GPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKIL 380 G P P P P P GQPG G PG A Sbjct: 409 GDEGP-PGISIPGP-PGLDGQPGA-------PGLPGPPGPAG------------------ 441 Query: 381 PERPPSAQDGLGSTRGPPSSLPQRHFPG-QAYRASGVDTSPGPPDTELAAPGPPPARLPQ 439 P PPS + GPP S + G Q + DT T ++ P P LP Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPG-LPG 500 Query: 440 LWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGME 499 L P PPG L GQ LP P P ++ P + Sbjct: 501 L--------PGPPGS-LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI- 550 Query: 500 MLSRLPFPA-GGPEWQGGSQGALGTAGK--TPGPREKLPAVRSSQGGSPALFTYNGMTDP 556 L FP G + + GS GA G G TPG ++ LP + +G P T+ G P Sbjct: 551 ----LTFPGMKGDKGELGSPGAPGLPGLPGTPG-QDGLPGLPGPKG-EPGGITFKGERGP 604 Query: 557 GAQPLFFGVAQPQVSPHGTPSLPPPRVVG--------ASPSESPLPSPATNTAGSTCSSL 608 P G+ + P G P PP VG +P + +P P + + Sbjct: 605 PGNPGLPGLPG-NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPG 663 Query: 609 SPMSSSPANPSSE-ESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAK 667 P P NP + + LPG G P P G P P LP P+ Sbjct: 664 KP--GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP---GIPGIGLPGPPGPKGFP 718 Query: 668 AFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQL 727 P P G G LE P P P G G GF PP P Sbjct: 719 GIPGPPGAPGTPGRIG-LEGPPGPPGFP--GPKGEPGFALPGPPGPP------------- 762 Query: 728 DVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAH 787 L F A G + PGPPG P +P Sbjct: 763 --------------GLPGFKG---------ALGPKGDRGFPGPPGPPGRTGLDGLPGPK- 798 Query: 788 AGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITE- 846 GD G+ P+ LP + P P + I + Sbjct: 799 -------------GDVGPNGQPGPMGPPGLPGIGVQGPPGPPG---------IPGPIGQP 836 Query: 847 ALNGMEYQSDNPEIDSSFIDVFADEEPS-------GPRGPSSGHPLKSKAGVT--PESKA 897 L+G+ + +P + E S GP GP L KAG + P +K Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896 Query: 898 PPPLPAATPDPQTPR--PGDRGCPA-------RGRPKTRSLGLAPTEADAPSQGRQQRRG 948 + P P P PG G P +G+P GL + S+G G Sbjct: 897 EMGM-MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP-----GLPGPTGEKGSKGEPGLPG 950 Query: 949 KQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERP--PPRPRRPRTQAP-GSR 1005 + L S G G G SG P+ GL P P +P P G + Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIPGVSG--PKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008 Query: 1006 ADPA-PRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREY 1064 +P P P P + P + G G+ + QK + Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068 Query: 1065 DFASESEEDEQPPPRG-------------------PGFRGRRGRGEKRKEVELTQGPRED 1105 +S P P+G PG G G + + L P Sbjct: 1069 GISSIGLPG-LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP 1127 Query: 1106 EPQKPRKAARQEAGGDGAPANPEEPG----GSRPGPGRSPQARG-PSRSLETGAAAREGG 1160 P P+ + G G P P EPG G PG P +G P + G A ++G Sbjct: 1128 GPPGPKGIS----GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE 1183 Query: 1161 PKCADRPSVAPKDPLQVP-TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRS 1219 P +P P +P + + + P + P P E + Sbjct: 1184 P---GQPGFGNPGPPGLPGLSGQKGDGGLPGI--PGNPGLPGPKGEPGFHGFPGVQGPPG 1238 Query: 1220 PPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGG 1279 PP + + G P+ PP G P P+G P G PG G + G G Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPP------GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGN 1292 Query: 1280 TQAP 1283 P Sbjct: 1293 PGQP 1296 Score = 82.8 bits (203), Expect = 6e-15 Identities = 173/692 (25%), Positives = 218/692 (31%), Gaps = 157/692 (22%) Query: 1 MPGERPRGAPP----PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQ 56 +PGE+ PP P G+ + +PG P PP P G G+ Sbjct: 841 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMG 899 Query: 57 AMELPEAQPRQARDGELKPPSLRGQ----------APSSTPGKRGSPQTPPGRSPLQAPS 106 M P G P L+G P+ G +G P P P+ P+ Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-PN 958 Query: 107 RLAGRAE-GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG 165 L + E G P I G++ + L P P L P + P GP G P PG Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ--PGLPGPPGP-KGNPGLPG 1015 Query: 166 LPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSY- 224 P P + + + P PP P + SP PG Sbjct: 1016 QPGLIGPPGLK------------GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKG 1063 Query: 225 ----PEYQASGADSWP-PAAENSFPG--ANFGVPPAEPEPIPKGSRPG--GSPRGVSFQF 275 P + G P P E PG N G+ + +P PG G+P G Q Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP----GLPGLPGTP-GAKGQP 1118 Query: 276 PFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPL 335 P G P P ++G G P P VG G P QP P Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPG-------LPGEPGP---VGGGGH---PGQPGP--- 1162 Query: 336 PCYQGQPG--GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGS 393 P +G+PG G+ + G PG + P + LP P GL Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP--GNPGLPG 1220 Query: 394 TRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPG 453 +G P FPG GPP GPP + P L P P P P Sbjct: 1221 PKGEPGF---HGFPGVQ----------GPP-------GPPGSPGPALEGPKGNPGPQGPP 1260 Query: 454 GPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP-- 511 G RP P G + LP P G P Sbjct: 1261 G-------------------------------------RPGPTGFQ---GLPGPEGPPGL 1280 Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQG-----GSPALFTYNGMT-DPG--AQPLFF 563 GG +G G G+ P LP ++ QG G+P NGM DPG P F Sbjct: 1281 PGNGGIKGEKGNPGQPGLP--GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP 1338 Query: 564 GVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623 G+ P P P ++G P LP P S S + A P Sbjct: 1339 GMKGPSGVPGSAGPEGEPGLIG-PPGPPGLPGP---------SGQSIIIKGDAGPPGIPG 1388 Query: 624 Q-----LPGPLGPSAF---FHPPTHPQETGSP 647 Q LPGP GP PP P G P Sbjct: 1389 QPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1420 Score = 62.8 bits (151), Expect = 7e-09 Identities = 315/1316 (23%), Positives = 396/1316 (30%), Gaps = 210/1316 (15%) Query: 309 PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGA-AHSAP 365 P+G ++ + GP P + P LP + G PG G+ H G PG Sbjct: 73 PRGQKGDDGI-PGPPGPKGIRGPPG-LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130 Query: 366 RPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT 425 R F S P P GL GPP + PG +S PGP Sbjct: 131 RGFPGS---------PGFP-----GLQGPPGPPGIPGMKGEPGSIIMSS----LPGPKGN 172 Query: 426 ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLP-------- 477 PGPP + L PT P P P GP G P P + L Sbjct: 173 P-GYPGPPG--IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229 Query: 478 -----QSAPLPWPQVLPTARP----------------SPHGMEMLSRLPFPAGGPEWQGG 516 Q P P Q+ RP P G + P P GG + + G Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289 Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPG--AQPLFFGVAQPQVSPHG 574 QG G GK PG + + G P + G DPG +P G + Q G Sbjct: 290 EQGEPGKRGK-PG--------KDGENGQPGIPGLPG--DPGYPGEPGRDG-EKGQKGDTG 337 Query: 575 TPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634 P PP +V +P P T G T + E PG GP Sbjct: 338 PPG--PPGLV--------IPRPGT---GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL 384 Query: 635 FHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEG 694 PP G P P P + P + P P GL + L P P G Sbjct: 385 PGPP-GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLDGQPGAPGLPGPPGP-AG 441 Query: 695 PEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQLDVLLTCRQC-------DRNYSSLAAF 746 P + P P PP L + D TC C L Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501 Query: 747 LAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPA-DAHAGLLSHAKTFL-LAGDAQ 804 G + + G + GP GLP P AP P G TF + GD Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561 Query: 805 AEGKDDPLRTGFLPSLAATPFP--LPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDS 862 G P G LP L TP LP + + G NP + Sbjct: 562 ELG--SPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGI------TFKGERGPPGNPGLPG 612 Query: 863 SFIDVFADEEPS-GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDP-----QTPRPGDR 916 ++ P GP GP ++ AG + P +P DP Q +PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAG----NPGQPGIPGPKGDPGQTITQPGKPGLP 668 Query: 917 GCPAR----GRPKTRSLGLAPTEADAP-SQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971 G P R G P L P P S+G G L G G+ G Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRL 1030 GL E PP P P + PG P P R Sbjct: 729 TPGRIGL---------EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 1031 PPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRG 1090 P P R G G + + Q + + PP PG G+ G Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839 Query: 1091 EKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL 1150 E P D P P R G GAP P P GS PG++ + P Sbjct: 840 GIPGEKGDPGPPGLDVPGPP--GERGSPGIPGAP-GPIGPPGSPGLPGKAGASGFPGTKG 896 Query: 1151 ETGAAAREGG------PKCADRPSVAPKDPLQ----VPTNT-ETSEETRPSLDFPQEAKE 1199 E G G P + P + D LQ +P T E + P L P + Sbjct: 897 EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956 Query: 1200 P-------ETAEESAP-----DSTEFTEALRSPPAACAGEMGAS--PGLLIPEQP----- 1240 P E E P + + L P G+ G S PGL P P Sbjct: 957 PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP----GQPGLSGQPGLPGPPGPKGNPG 1012 Query: 1241 -PPSRHDTGTPKPSGSLAN---TAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQ- 1295 P G P G++ + P G PG + G PG P K P Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072 Query: 1296 ---PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPH 1352 PG P P P + + DP G P G P AK P P Sbjct: 1073 IGLPG-LPGPKGEPGLPGYPGNPGIKGSVG----DP-GLPGLP-GTPGAKGQPGLPGFPG 1125 Query: 1353 SELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETE 1412 + GPK ++G PP + + G G P P PPG + + Sbjct: 1126 TPGPPGPKGISG---------------PPGNPGLPGEPGPVGGGGHPGQP-GPPG-EKGK 1168 Query: 1413 PGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANR-DSGLPFACADPPQKTVPSDPPYP 1471 PG+ P PP LS + D GLP +P +P + Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228 Query: 1472 SFLLLEEVSPMLPSHFPDLSGGK-VLSKTCPPER--------TVVPGAAPSLPGKG 1518 F ++ S P L G K PP R P P LPG G Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNG 1284 Score = 57.0 bits (136), Expect = 4e-07 Identities = 116/457 (25%), Positives = 139/457 (30%), Gaps = 77/457 (16%) Query: 20 PRQVASSPGHPSQPPLEDNT--PATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPS 77 P+ PG+P P ++ + P G A GQ P G PP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP---------GTPGPPG 1131 Query: 78 LRG-QAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDET 136 +G P PG G P G P + G P Q I G A + +P Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK--GKPGQDGIPGPAGQKGEPG---Q 1186 Query: 137 PENPQLEAAQLPEVDTPQGPG--TGAPLRPGLPRTEAQPAAEELGFHRC--FQEPPSSFT 192 P LP + +G G G P PGLP + +P GFH Q PP Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP-----GFHGFPGVQGPPG--- 1238 Query: 193 STNYTSPSATPRPPAPGPPQSRGTS--PLQPGSYPEYQASGADSWPPAAENSFPGANFGV 250 P +P P GP + G P +PG G + P N G Sbjct: 1239 ------PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGN 1292 Query: 251 PPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQ 310 P P G + P G+ P L+G P V G GP P Sbjct: 1293 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV----PG 1348 Query: 311 GAWPEEAVGT-GPAYPLPTQPAPSPLPCY---QGQPGGLNRHSDLSGALSSPGAAHSAPR 366 A PE G GP P P P PS P G+ L G L P P Sbjct: 1349 SAGPEGEPGLIGPPGP-PGLPGPSGQSIIIKGDAGPPGIPGQPGLKG-LPGPQGPQGLPG 1406 Query: 367 PFSDSLHKSLTKILPERPPSAQ-----DGLGSTRGPPSSLPQRHFPGQAYRAS------- 414 P P P DG G +G P PGQ Sbjct: 1407 PTG-----------PPGDPGRNGLPGFDGAGGRKGDPG------LPGQPGTRGLDGPPGP 1449 Query: 415 -GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT 450 G+ PGPP T A G R Q D P T Sbjct: 1450 DGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1486 Score = 52.0 bits (123), Expect = 1e-05 Identities = 117/458 (25%), Positives = 144/458 (31%), Gaps = 74/458 (16%) Query: 3425 VRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLC 3484 + +PG PG L G P + V +PG PG+ P G E +P + Sbjct: 659 ITQPGKPG-----LPGN-PGRDGDVGLPGDPGLPGQPGLP--GIPGSKGEPGIPGI---- 706 Query: 3485 SEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALD 3544 P KG+P P P T G E P P P P AL G L Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP-GFALPGPPGPPGLP 765 Query: 3545 G---ALERPENEASPGSPGPLLQQALPLGASLPRP----GARGQDAEGKRAPLVFSGKRR 3597 G AL + PG PGP + L LP P G GQ L G + Sbjct: 766 GFKGALGPKGDRGFPGPPGPPGRTGLD---GLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822 Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSA 3657 PG G P H + EK + GP G +GS P Sbjct: 823 PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG--ERGSPGIPG----------- 869 Query: 3658 ASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717 A P P P KA S PG T+ M P PGP S PG K Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPG-----TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 3718 GGSQPQPA-------SGQLQSETATTPAKPSFPS--------RSPAPERLPARAQAKSCT 3762 G Q QP G P P P+ P +P + K Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 3763 KGPREAGEQGPHGSLG----PKEKGESSTKRKKGQVPGPARSESVGSFG-RAPSAPDKPP 3817 P + G+ G G G P KG + G + P ++G G P + PP Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 PS V P P P + K +PG Sbjct: 1045 -------GPSGV------PGQPGSPGLPGQKGDKGDPG 1069 Score = 51.6 bits (122), Expect = 2e-05 Identities = 170/687 (24%), Positives = 226/687 (32%), Gaps = 102/687 (14%) Query: 871 EEPSGPRGPSSGHPLKSKAGVTPES-KAPPPLPAATPDPQTP-RPGDRGCPA-RGRPKTR 927 E P GPRG + G P+ + PP LP P P PG G P +G P Sbjct: 68 EGPPGPRGQKGDDGIPGPPG--PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIP--- 122 Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR-PRRNDGL 986 G T+ + G G Q G G G S L P+ N G Sbjct: 123 --GCNGTKGERGFPGSPGFPGLQ-----GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY 175 Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046 P + T PG P P P + + P+ K G Sbjct: 176 PGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235 Query: 1047 GKELILKIVQQKNRLREYDFASESE--EDEQPPPRGPGFRGRRG--RGEKRKEVELTQGP 1102 G + ++ R + +F + ++ PP PG RG G GEK ++ E Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----- 290 Query: 1103 REDEPQKPRKAARQ-EAGGDGAPANPEEPGGSRPG-PGRSPQARGPSRSLETGAAAREG- 1159 + EP K K + E G G P P +PG PG PGR + + +TG G Sbjct: 291 -QGEPGKRGKPGKDGENGQPGIPGLPGDPG--YPGEPGRDGE---KGQKGDTGPPGPPGL 344 Query: 1160 -GPKCADRPSVAPKDPLQVP-TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217 P+ ++ K + +P E E P + P P A P Sbjct: 345 VIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG------- 397 Query: 1218 RSPPAACAGEMG-----ASPGLLIPEQP-----PPSRHDTGTPKPSG-------SLANTA 1260 P GE G PG+ IP P P + G P P+G + Sbjct: 398 ---PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454 Query: 1261 PHGSSPTPGVGSLLGGPG--GTQAPVSHN----SKDPPARQPGEFLAPVANPSSTACPKP 1314 P G +PG L G G G + N P QPG P P S P Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP-GPPGSLGFPGQ 513 Query: 1315 SVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL-FLGPKDLAGCFLEELHPK 1373 + + G P G P G P A P P L F G K G EL Sbjct: 514 KGEKGQAGATG--PKGLPGIP-GAPGAPGFPGSKGEPGDILTFPGMKGDKG----EL-GS 565 Query: 1374 PSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPG--TAETEPGRAASPPTLESSSLFPDL 1431 P A P + G+D P P+ PG T + E G +P P L Sbjct: 566 PGAPGLPGLPGT----PGQDGLPGLPG-PKGEPGGITFKGERGPPGNPG-------LPGL 613 Query: 1432 P--VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD 1489 P + PP +G + G+ +P Q +P P + + P LP + P Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN-PG 672 Query: 1490 LSGGKVLSKTCPPERTVVPGAAPSLPG 1516 G L P +PG P LPG Sbjct: 673 RDGDVGL-----PGDPGLPG-QPGLPG 693 Score = 47.8 bits (112), Expect = 2e-04 Identities = 113/463 (24%), Positives = 147/463 (31%), Gaps = 74/463 (15%) Query: 3432 GQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPST 3491 G K E P +PG PGP E P PRG + +P P Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGF-PGP-EGPPGPRGQK---GDDGIPGPPGPKGIRGPPG 96 Query: 3492 TKGWPETLERPV------DPVTHPIRGCELPSNHQECPP----PSLS--PFPAALADGRG 3539 G+P T P P I GC + P P L P P + +G Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-------------RPGARGQDAEGK 3586 + P + +PG PGP Q LP +P PG G Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 3587 RAPLVFSGKRRAPGARGRCAP-----DHFQEDHLLQKEKEVSSSHMVSEGGPRG-TFHKG 3640 L F G + G +G P ++ + E + + + GP G +G Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 3641 SATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA-----PGELARGTENGMKPAT 3695 P G + ++ K K + + + L PGE R E G K T Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT 336 Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755 PGP G PRPGT G + L E + FP P LP Sbjct: 337 --GPPGP--PGLVIPRPGTGITIGEKGNIGLPGLPGE----KGERGFPG-IQGPPGLP-- 385 Query: 3756 AQAKSCTKGPREAGEQGPHGSLG-PKEKGESSTKRKKG-QVPGPARSESVGSFGRAPSAP 3813 GP A GP G G P E+G+ + G +PGP + P AP Sbjct: 386 --------GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG------QPGAP 431 Query: 3814 DKP-PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 P P P P +P P P PP S K G Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGP-----PGPPGSPGDKGLQG 469 Score = 47.8 bits (112), Expect = 2e-04 Identities = 95/368 (25%), Positives = 119/368 (32%), Gaps = 95/368 (25%) Query: 3427 RPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPR-GSSPILSEGSLPALLHLCS 3485 +PG PG+K + + +P + PG PG G PP G S +G LP + Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQ-PGFGNPGPPGLPGLSGQKGDGGLPGI----- 1212 Query: 3486 EVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDG 3545 G P +P H G + P P P SP PA L+G Sbjct: 1213 -------PGNPGLPGPKGEPGFHGFPGVQGP------PGPPGSPGPA----------LEG 1249 Query: 3546 ALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA-EGKRAPLVFSGKRRAPGARGR 3604 P + PG PGP Q LP G P PG G +G++ G PG +G Sbjct: 1250 PKGNPGPQGPPGRPGPTGFQGLP-GPEGP-PGLPGNGGIKGEKGNPGQPGLPGLPGLKG- 1306 Query: 3605 CAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKA 3664 + GP G +G+ +P G D P Sbjct: 1307 -------------------------DQGPPGL--QGNPGRP-GLNGMKGDPGLPGVPG-- 1336 Query: 3665 LKFP--VHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQ-----GSGSP-----RP 3712 FP P GS P G + P P PGPS Q G P +P Sbjct: 1337 --FPGMKGPSGVPGSAGP----EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQP 1390 Query: 3713 GTKTGGGSQ-PQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ 3771 G K G Q PQ G P+ P P LP A P G+ Sbjct: 1391 GLKGLPGPQGPQGLPG------------PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1438 Query: 3772 GPHGSLGP 3779 G G GP Sbjct: 1439 GTRGLDGP 1446 Score = 44.7 bits (104), Expect = 0.002 Identities = 115/475 (24%), Positives = 140/475 (29%), Gaps = 62/475 (13%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG PG + LP PG GE PP P L L + Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN-----------PGLPGLPGNI 617 Query: 3488 APSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546 P G+ P PV I+G P P P G+ L G Sbjct: 618 GPMGPPGF-----GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP--GLPGN 670 Query: 3547 LERPENEASPGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF---SGKRRAPGAR 3602 R + PG PG Q LP + S PG G G P F G APG Sbjct: 671 PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730 Query: 3603 GRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS 3662 GR + K + GP G A P G DR P Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPG 784 Query: 3663 ----------KALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP 3712 K V P G + P L G P P PGP Q P Sbjct: 785 PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG--PPGPPGIPGPIGQPGLHGIP 842 Query: 3713 GTKTGGGSQPQPASGQL-QSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ 3771 G K G G + + P P P P LP +A A E G Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMM 901 Query: 3772 GPHGSLGPKE----------KGESSTKRKKGQVPGPARSESVGSFGR----APSAPDKPP 3817 GP G GP KG+ + + G +PGP + GS G P P P Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEK--GSKGEPGLPGPPGPMDPN 958 Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 K LP P + + P + +PG + + G P+G P Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLPGPPGPKGNP 1011 Score = 43.9 bits (102), Expect = 0.003 Identities = 117/515 (22%), Positives = 162/515 (31%), Gaps = 75/515 (14%) Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLP 3478 P ++G+ PG PGQ + + LP PG PG PP G + + P Sbjct: 980 PKGYQGL--PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP--GLKGTIGDMGFP 1035 Query: 3479 ALLHLCSEVAPSTTKGWPETLERPV------DPVTHPIRGCELPSNHQECPPPSLSPFPA 3532 + PS G P + P DP I LP E P L +P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE---PGLPGYP- 1091 Query: 3533 ALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAE------- 3584 G+ + G++ P PG+PG Q LP P P G +G Sbjct: 1092 ------GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145 Query: 3585 GKRAPLV---FSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRG----TF 3637 G+ P+ G+ PG +G+ D +K GP G + Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP---AGQKGEPGQPGFGNPGPPGLPGLSG 1202 Query: 3638 HKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPK 3697 KG P + P GS PG G + P P Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS--PGPALEGPKGNPGPQGPP 1260 Query: 3698 AKPGPSS-QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFP--------SRSPA 3748 +PGP+ QG P G P +G ++ E P +P P P Sbjct: 1261 GRPGPTGFQGLPGPE-------GPPGLPGNGGIKGEKG-NPGQPGLPGLPGLKGDQGPPG 1312 Query: 3749 PERLPARAQAKSCTKGPREAGEQGPHGSLGPK-EKGESSTKRKKGQV--------PGPA- 3798 + P R P G G G GP G + + + G + PGP+ Sbjct: 1313 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1372 Query: 3799 RSESVGSFGRAPSAPDKP--PRTPRKQATPSRVLPTKP--KPNSQNKPRPPPSEQRKAEP 3854 +S + P P +P P Q PT P P P + RK +P Sbjct: 1373 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1432 Query: 3855 GHTQRKDRLGKAFPQGRPLLR----PPKRGTAVHG 3885 G + G P G L+ PP + HG Sbjct: 1433 GLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHG 1467 Score = 43.5 bits (101), Expect = 0.004 Identities = 199/866 (22%), Positives = 253/866 (29%), Gaps = 161/866 (18%) Query: 1752 PGTADQPHR-GAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGR 1810 PG QP G P P P + + ++ G PP G+ QG + Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-------GSPGDKGLQGEQGVK 474 Query: 1811 A----------GGHLHPTAGRPGFEGNEFAPA-----------GASSLTAPRGREAWLVP 1849 G + G+PG G P G + T P+G L Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG----LPG 530 Query: 1850 VPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNP 1909 +P P + P L PG K + G G L +P + Sbjct: 531 IPGA-------PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583 Query: 1910 SGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGT 1969 GL G E G + +G PG + LP G +G G G +G EK Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG-PMGPPGFGPPGPVG--EKGIQGVA 640 Query: 1970 ANQLQPENGVSPGGTDNHASVNASPKTALTG--PTEGAVLLEKCKGSRAAMSLQ----EE 2023 N QP G+ D ++ K L G +G V L G L + Sbjct: 641 GNPGQP--GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698 Query: 2024 AEP------TPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077 EP P PP P G+ G TP R GL P G P P Sbjct: 699 GEPGIPGIGLPGPPGPK------GFPGIPGPPGAPG-TPGRI---GLEGPPGPPG-FPGP 747 Query: 2078 SVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137 G+ P P +P G L P +G G PPGP Sbjct: 748 K-GEPGFALPGPPGPPGLPGFKGAL-------GPKGDRGFPG-----------PPGP--- 785 Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDP 2197 P L+ G + + P+ PP L G +QG P P Sbjct: 786 ----PGRTGLDGLPGPKGDVGPNGQPGPMGPP-----------GLPGIGVQGPPGPPGIP 830 Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257 P G P L +P PG SP + GA P + Sbjct: 831 G--PIGQPGLHGIPGEKGDPGPPGLDVP---------GPPGERGSPGIPGAPGPIGPPGS 879 Query: 2258 TGL-----SSTPTGDEAQAG-RGLPGPD-----PQSRGAPPHTNPDRMPRGHSSYSPSNT 2306 GL +S G + + G G PGP P G P D + P+ Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939 Query: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKE-----PEDPGTPETGRSG 2361 G P +P L G L G G S + P DPG P G SG Sbjct: 940 KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP--GLSG 997 Query: 2362 ATKMPRVTCPSTGLGL----GRTTAP--SSTASDFQSDSPQSHRNASHQTPQGDPLGP-Q 2414 +P P GL G P T D PQ P G P P Sbjct: 998 QPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP--PGPSGVPGQPGS 1055 Query: 2415 DLKQRSRGYKKKPASTENGQWKGQAPHG-------PVTCEVCAASFRSG-PGLSRHKARK 2466 +G K P + G P G P + + G PGL K Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115 Query: 2467 HRP----HPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVT 2522 +P PG P P P + L + P H G+ P +G P Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH--PGQPGPPGEKGKPGQDG 1173 Query: 2523 QPPPAQGSKEVLRAPGSPHSQQLHPP 2548 P PA E PG P PP Sbjct: 1174 IPGPAGQKGE----PGQPGFGNPGPP 1195 Score = 42.4 bits (98), Expect = 0.009 Identities = 276/1195 (23%), Positives = 359/1195 (30%), Gaps = 236/1195 (19%) Query: 1684 GDSRPPQD-VCLPEPSKQPGPQLDAGSLAK---CSPDQELSFPKNKEAASSQESEDSLRL 1739 G PP D +C P P PG D G + + F S + L Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500 Query: 1740 LPCEQRGGFLPEPG-TADQPHRGAPAPEAFGSPAVHLAPDL-AFQGDGAPPLDATWPFGA 1797 LP G L PG ++ GA P+ G P + AP F G P D F Sbjct: 501 LPGPP--GSLGFPGQKGEKGQAGATGPK--GLPGIPGAPGAPGFPGSKGEPGDIL-TFPG 555 Query: 1798 SPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLV------PVP 1851 + S G G G PG G + G L P+G + P Sbjct: 556 MKGDKGELGSPGAPG-----LPGLPGTPGQD----GLPGLPGPKGEPGGITFKGERGPPG 606 Query: 1852 SPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGL--QELTPAAQSPP---- 1905 +P P + PP PGP K G+ G Q P + P Sbjct: 607 NPGL-----PGLPGNIGPMGPP--GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659 Query: 1906 -RVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQ----LGLEA-DGHWGLLG 1959 + GL G G V G PG + +P G +GL G G G Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719 Query: 1960 QAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMS 2019 GT ++ E P G P AL GP L G + A+ Sbjct: 720 IPGPPGAPGTPGRIGLE---GPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGALG 772 Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSV 2079 + + P PP P + L G G+ P PGL P + P P Sbjct: 773 PKGD-RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGL--PGIGVQGPPGPP- 827 Query: 2080 GDLAACAPSPTSAAH-MPCSLG-PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137 P H +P G P P + P +G G +P +P PPG Sbjct: 828 ---GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG--IPGAPGPIGPPG---- 878 Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDP 2197 SP A G T P PP P + + G L+G+ P Sbjct: 879 ---SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP--GRSGVPG--LKGDDGLQGQP 931 Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257 P T + + L P L S G P L G S Sbjct: 932 GLPGP--------TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGY 983 Query: 2258 TGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAV 2317 GL P GLPGP P +G P P +G Sbjct: 984 QGLPGDPGQPGLSGQPGLPGP-PGPKGNPG--------------LPGQPGLIG------- 1021 Query: 2318 TAVPTEPPTLQGA----GPDSPACLEGEMGTSS--KEPEDPGTPETGRSGATKMPRVTCP 2371 PP L+G G P +EG G S +P PG P G+ G P + Sbjct: 1022 ------PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP--GQKGDKGDPGI--- 1070 Query: 2372 STGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTE 2431 + +GL P + P N + GDP P G P + Sbjct: 1071 -SSIGLPGLPGPKG-----EPGLPGYPGNPGIKGSVGDPGLP--------GLPGTPGA-- 1114 Query: 2432 NGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRP-HPGAPAEPSPAALPAQQPLEP 2490 KGQ P P F PG K P +PG P EP P P +P Sbjct: 1115 ----KGQ-PGLP--------GFPGTPGPPGPKGISGPPGNPGLPGEPGPVG-GGGHPGQP 1160 Query: 2491 LAQKCQPPRKK----SHRVSGKERPNHSRGDPSHVTQPPPA----QGSKEVLRAPGSPHS 2542 PP +K + G G P PP G K PG P + Sbjct: 1161 -----GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGN 1215 Query: 2543 QQLHPP--SPTEHEV-DVKTPASKP-RPDQAREDELHPKQAEKREGRRWRREPT----VD 2594 L P P H V+ P P P A E PK +G R PT + Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG---PKGNPGPQGPPGRPGPTGFQGLP 1272 Query: 2595 SPSHSEGKSNKKRGKLRGRRLRE-ESILPVSADVISDGRGSRPSPAMASYAASPSHCLSV 2653 P G G ++G + + LP + +G + P + P + Sbjct: 1273 GPEGPPGLPG--NGGIKGEKGNPGQPGLPGLPGL----KGDQGPPGLQGNPGRPG-LNGM 1325 Query: 2654 EGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALG 2713 +G P G P GP + G+A + GE G PPG L PG + + Sbjct: 1326 KGDPGLPG-VPGFPGMKGPSGVPGSAGPE------GEPGLIGPPGPPGL-PGPSGQSIII 1377 Query: 2714 EQPTGQKG----ASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPPL 2769 + G G +G GP+ + L P Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQGL-----------------------------PGPT 1408 Query: 2770 GPLGFPETSSSPADSTTSSCL--QGLPDNPDTQG--------GVQGPEGPTPDAS 2814 GP G P + P GLP P T+G G+QGP GP +S Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1463 Score = 40.4 bits (93), Expect = 0.035 Identities = 56/209 (26%), Positives = 69/209 (33%), Gaps = 18/209 (8%) Query: 3693 PATPKAKPGPSSQGSG---SPRPGTKTGGGSQPQPASGQLQSETATT----PAKPSFPSR 3745 P P PG + S PG K G P L T P P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 3746 SPAPERLPA-RAQAKSCTKGPR-EAGEQGPHGSLGP-----KEKGESSTKRKKGQ--VPG 3796 P P LP + +GP+ E GEQG G GP ++K + +KG +PG Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 3797 PARSESVGSFGRAPSAPDKPPRTPRKQATPS-RVLPTKPKPNSQ-NKPRPPPSEQRKAEP 3854 P P +Q P R P K N Q P P EP Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324 Query: 3855 GHTQRKDRLGKAFPQGRPLLRPPKRGTAV 3883 G K + G P G P L P+ GT + Sbjct: 325 GRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353 Score = 37.7 bits (86), Expect = 0.23 Identities = 50/197 (25%), Positives = 62/197 (31%), Gaps = 35/197 (17%) Query: 489 PTARPSPHGMEMLSRLPFPAG-----GPEWQGGSQGALGTAGK-----TPGPREKLPAVR 538 P P P G + +P P G GP G G G G PGP + +P Sbjct: 67 PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP-QGIPGCN 125 Query: 539 SSQG-----GSPALFTYNGMTDPGAQPLFFG-----VAQPQVSPHGTPSLPPPRVVGASP 588 ++G GSP G P P G + P G P P P + P Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP 185 Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSA--FFHPPTHPQETGS 646 + +P P P P P LPGP G F P E G Sbjct: 186 GPTGIPGPIGPPG-------PPGLMGPPGPPG----LPGPKGNMGLNFQGPKGEKGEQGL 234 Query: 647 PFPSPEPPHSLPTHYQP 663 P P PP + +P Sbjct: 235 QGP-PGPPGQISEQKRP 250 Score = 37.0 bits (84), Expect = 0.39 Identities = 169/712 (23%), Positives = 217/712 (30%), Gaps = 136/712 (19%) Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASA 3265 P P+ G R G PG P + PG P P + DGA P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH-DGAPGPQGIPG 123 Query: 3266 T--ALADAGSPGPP-----RTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCG--- 3315 + G PG P + P P P GEP + + + P + + G Sbjct: 124 CNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKGNPGYPGPPG 180 Query: 3316 -KRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLY 3374 + P P + + P + P P + G + + G G LQ P Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240 Query: 3375 ACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGAP--G 3432 ++ I + F K +Q L G R P G+R P P G Sbjct: 241 PGQISEQKRPI----------DVEFQKGDQ-------GLPGDRGPPGPPGIRGPPGPPGG 283 Query: 3433 QKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTT 3492 +K E P KR + PG+D E P + Sbjct: 284 EKGEKGEQGEPGKRGK---------PGKD-----------GENGQPGI------------ 311 Query: 3493 KGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA--LADGRGDCALDGAL--- 3547 G P P +P +G + PP + P P +G+ L G Sbjct: 312 PGLPGDPGYPGEPGRDGEKG-QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370 Query: 3548 -ER--PENEASPGSPGPLLQQALPLGASLPR--PGARGQDAEGKRAPLVFS-----GKRR 3597 ER P + PG PGP A +G P PG RGQ +G P S G Sbjct: 371 GERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQ--KGDEGPPGISIPGPPGLDG 426 Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR-- 3655 PGA G P H + S + E GP G G Q D+ Sbjct: 427 QPGAPGLPGPPGPAGPH-------IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479 Query: 3656 -------SAASTPSKALKFPVHPRKAVGSLA----PGELARGTENGMK--PATPKAKPGP 3702 + S P P P GSL GE + G K P P A P Sbjct: 480 TCFNCIGTGISGPPGQPGLPGLPGPP-GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538 Query: 3703 SSQGS-GSPR-----PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756 GS G P PG K G P + L T P + P P P+ P Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGL-PGPKGEPGGI 596 Query: 3757 QAKSCTKGPR----------EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSF 3806 K +GP G GP G P GE + G P G Sbjct: 597 TFKG-ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655 Query: 3807 GRAPSAPDKP--PRTPRKQATPSRVLPTKP-KPNSQNKPRPPPSEQRKAEPG 3855 G+ + P KP P P + LP P P P P S K EPG Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVG--LPGDPGLPGQPGLPGIPGS---KGEPG 702 Score = 36.2 bits (82), Expect = 0.66 Identities = 105/488 (21%), Positives = 148/488 (30%), Gaps = 82/488 (16%) Query: 2101 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLAC-----------------SPA 2143 P P+ P + ++ + G G P P + PPGP + +P Sbjct: 116 PGPQGIPGCNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPG 174 Query: 2144 WAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP----KEALAGCLLQG-EGSPLEDPS 2198 + G+ T P PP L P P + G QG +G E Sbjct: 175 YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGL 234 Query: 2199 SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRAT 2258 PPG ++ + + + + L G P + G P + Sbjct: 235 QGPPGPPGQIS-------EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287 Query: 2259 GLSSTPTGDEAQAGR----------GLPGPDPQSRGAPPH---------TNPDRMPRGHS 2299 G + G+ GLPG DP G P T P P G Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPP-GLV 345 Query: 2300 SYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDP-GTP-ET 2357 P +G + + +P E G P L G G + P P G P E Sbjct: 346 IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405 Query: 2358 GRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLK 2417 G+ G P ++ P G+ AP + H S + + P GP Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGP---HIPPSDEICEPGPPGPPG-- 460 Query: 2418 QRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGP----GLSRHKARKHRPHPGA 2473 S G K KG TC C + SGP GL PG Sbjct: 461 --SPGDKGLQGEQGVKGDKGD------TCFNCIGTGISGPPGQPGL-----------PGL 501 Query: 2474 PAEPSPAALPAQQPLEPLAQKCQPPRKKS-HRVSGKERPNHSRGDPSHVTQPPPAQGSKE 2532 P P P Q+ + A P G S+G+P + P +G K Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561 Query: 2533 VLRAPGSP 2540 L +PG+P Sbjct: 562 ELGSPGAP 569 Score = 34.3 bits (77), Expect = 2.5 Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 16/133 (12%) Query: 3183 LGDLPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240 L LPG G +G + + P PK G G PG G + PG Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 3241 ERAKPRARSTPS--------NPDGAATPDSASATALA----DAGSPGPPRT--TPSPSPD 3286 E+ KP P G P L+ D G PG P P P + Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224 Query: 3287 PWAGGEPLLQATP 3299 P G P +Q P Sbjct: 1225 PGFHGFPGVQGPP 1237 Score = 33.9 bits (76), Expect = 3.3 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 16/121 (13%) Query: 3186 LPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAKKDS 3238 LPG GL G + + + P P+ G G PG P G +G+ S Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072 Query: 3239 PGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQAT 3298 G P + P P P ++ D G PG P T P A G+P L Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKG--SVGDPGLPGLPGT-------PGAKGQPGLPGF 1123 Query: 3299 P 3299 P Sbjct: 1124 P 1124 Score = 33.1 bits (74), Expect = 5.6 Identities = 22/55 (40%), Positives = 22/55 (40%), Gaps = 3/55 (5%) Query: 1232 PGLLIPEQPPPSRH---DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283 PG PE PP R D G P P G P G PG L G PG AP Sbjct: 62 PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 101 bits (252), Expect = 1e-20 Identities = 326/1413 (23%), Positives = 429/1413 (30%), Gaps = 239/1413 (16%) Query: 1 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60 +PG P G P P G P + PG P P + N +G + G+ Q ++ Sbjct: 184 LPG--PTGIPGPI--GPPGPPGLMGPPGPPGLPGPKGNMGLN--FQGPKGEKGE-QGLQG 236 Query: 61 PEAQPRQARDGELKPPSLRGQ-APSSTPGKRGSPQTPPGRSPLQAPSRLAGRA--EGSPP 117 P P Q + + +P + Q PG RG P P R P P G +G P Sbjct: 237 PPGPPGQISE-QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295 Query: 118 QRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGL--PRTEAQPAA 175 +R G +P + P +P + + Q TG P PGL PR Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355 Query: 176 EELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSW 235 E G P P P PGPP + P P +P + D Sbjct: 356 GEKGN---IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEG 412 Query: 236 PPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGH 295 PP P G P A P P G P G S + P G P + G Sbjct: 413 PPGISIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470 Query: 296 AFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-----LPTQPAPSPLPCYQGQPG------- 343 G +G +GTG + P LP P P + GQ G Sbjct: 471 QGVKG--------DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522 Query: 344 -GLNRHSDLSGALSSPGAAHSAPRP-----------FSDSLHKSLTKILPERPPS-AQDG 390 G + GA +PG S P L LP P + QDG Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582 Query: 391 LGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT--ELAAPGPPPARLP---------- 438 L GP F G+ G +PG P + GPP P Sbjct: 583 LPGLPGPKGEPGGITFKGE----RGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQG 638 Query: 439 QLWDPTAAPYPTPPGGP---LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP------ 489 +P P P G P + G P + LP LP LP Sbjct: 639 VAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698 Query: 490 -------TARPSPHGMEMLSRLPFPAGGPEWQG--GSQGALGTAGKTPGPREKLPAVRSS 540 P P G + +P P G P G G +G G G PGP+ + Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG-FPGPKGEPGFALPG 757 Query: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQP--------------QVSPHGTPS-LPPPRVVG 585 G P L + G P F G P V P+G P + PP + G Sbjct: 758 PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817 Query: 586 ----ASPSESPLPSPATNTA-----GSTCSSLSPMSSSPANPSSEESQ----LPGPLGPS 632 P +P P G P P P S PGP+GP Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877 Query: 633 AFFHPPTHPQETG-SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691 P P + G S FP + + P P + G +G + P Sbjct: 878 G---SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934 Query: 692 HEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQ 751 E G G G P PP P L S + + + + Sbjct: 935 GPTGEKGSKGEPGLP--GPPGPMDPNLLGSKG----------EKGEPGLPGIPGVSGPKG 982 Query: 752 FCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGD---AQAEGK 808 + GL + G PG PG P P P +P GL+ GD +G Sbjct: 983 YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP--GQPGLIGPPGLKGTIGDMGFPGPQGV 1040 Query: 809 DDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVF 868 + P +P +P LP D + D + S+ L G + + P + Sbjct: 1041 EGPPGPSGVPGQPGSP-GLPGQKGD-KGDPGISSIGLPGLPGPKGEPGLPGYPGN----- 1093 Query: 869 ADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPA--ATPDPQTPR-----PGDRGCPAR 921 G +G S G P TP +K P LP TP P P+ PG+ G P Sbjct: 1094 -----PGIKG-SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP-- 1145 Query: 922 GRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPR 981 G P G P + P G + + G+ G G+ G GL + Sbjct: 1146 GEPGPVGGGGHPGQPGPP--GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203 Query: 982 RNDGLGERPPPRPRRPRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRK 1040 + DG P P P + PG P + P PP Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG---------------PP-------- 1240 Query: 1041 ARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQ 1100 G+ G L + Q PP PGF+G G + Sbjct: 1241 ---GSPGPAL---------------EGPKGNPGPQGPPGRPGFQGLPG----------PE 1272 Query: 1101 GPREDEPQKPRKAA-RQEAGGDGAPANPEEPG--GSRPGPGRSPQARGPSRSLETGAAAR 1157 GP P P + E G G P P PG G + PG P R G Sbjct: 1273 GP----PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ---GNPGRPGLNGMKGD 1325 Query: 1158 EGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217 G P P + K P VP + E P L P P P Sbjct: 1326 PGLPGVPGFPGM--KGPSGVPGS--AGPEGEPGLIGP-----PGPPGLPGPSGQSIIIKG 1376 Query: 1218 RSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGP 1277 + P G+ G GL P+ P G P P+G + +G G G G P Sbjct: 1377 DAGPPGIPGQPGLK-GLPGPQGP------QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1429 Query: 1278 GGTQAPVSHNSKDPPARQPGEFLAPVANPSSTA 1310 G P + PP P P P +++ Sbjct: 1430 GLPGQPGTRGLDGPPG--PDGLQGPPGPPGTSS 1460 Score = 70.9 bits (172), Expect = 2e-11 Identities = 372/1580 (23%), Positives = 470/1580 (29%), Gaps = 321/1580 (20%) Query: 2 PGERPR----GAP-PPTMTGDLQPRQVASSPGHPSQP--PLEDNTPATRTTKGAREAGGQ 54 PG R + G P PP G P + PG P P P D P + G G+ Sbjct: 71 PGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130 Query: 55 AQAMELPEAQPRQARDGELKPPSLRGQAPS----STPGKRGSP--QTPPGRSPLQAPSRL 108 P Q G P ++G+ S S PG +G+P PPG L P+ + Sbjct: 131 RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGI 190 Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168 G P G+ P L N L Q P+ + + G P PG Sbjct: 191 PGPIGPPGPP----GLMGPPGPPGLPGPKGNMGLNF-QGPKGEKGEQGLQGPPGPPGQIS 245 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228 + +P E F + Q P R P PGPP RG PG Sbjct: 246 EQKRPIDVE--FQKGDQGLPGD-------------RGP-PGPPGIRGP----PG------ 279 Query: 229 ASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF 288 PP E G G P +P G G P G+ P G + Sbjct: 280 -------PPGGEKGEKGEQ-GEPGKRGKPGKDGEN--GQP-GIPGLPGDPGYPGEPGRDG 328 Query: 289 PADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348 G GP +P G LP + P QG PG Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG----- 383 Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS--AQDGLGSTRGPPSSLPQRHF 406 L G PGAA P PP + G GPP Sbjct: 384 --LPGP---PGAAVMGP----------------PGPPGFPGERGQKGDEGPPGI----SI 418 Query: 407 PGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG 466 PG G+D PG P PGPP P + P PPG P + Sbjct: 419 PGPP----GLDGQPGAP----GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470 Query: 467 QPSPGQR--LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTA 524 Q G + C + T P G L LP P G + G +G G A Sbjct: 471 QGVKGDKGDTCF---------NCIGTGISGPPGQPGLPGLPGPPGSLGFPG-QKGEKGQA 520 Query: 525 GKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVA--QPQVSPHGTPSLPPPR 582 G T GP+ LP + + G +P G +PG F G+ + ++ G P LP Sbjct: 521 GAT-GPKG-LPGIPGAPG-APGFPGSKG--EPGDILTFPGMKGDKGELGSPGAPGLPGLP 575 Query: 583 VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPG---PLGPSAFFHPPT 639 LP P G T +P P LPG P+GP F P Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG-----LPGNIGPMGPPGFGPPGP 630 Query: 640 -----------HPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEET 688 +P + G P P +P ++ +P P +G G + Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG-LPGNPGRDGDVGLPGDPGLPGQP 689 Query: 689 PFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLA 748 P G G+ G PP P + Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP------------------------- 724 Query: 749 HRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGK 808 G + G + PGPPG P P P F L G G Sbjct: 725 -----GAPGTPGRIGLEGPPGPPGFPGPKGEPG---------------FALPGPPGPPGL 764 Query: 809 DDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVF 868 P G L FP P LD L P+ Sbjct: 765 --PGFKGALGPKGDRGFPGPPGP---PGRTGLDGL------------PGPK--------- 798 Query: 869 ADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPA-RGRPKTR 927 D P+G GP G P GV PP P P P +PG G P +G P Sbjct: 799 GDVGPNGQPGPM-GPPGLPGIGVQG-----PPGPPGIPGP-IGQPGLHGIPGEKGDPGPP 851 Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLG 987 L + + S G G G G G ASG P +G Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPI-----------GPPGSPGLPGKAGASGF-PGTKGEMG 899 Query: 988 ERPPPRPRRP-----RTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042 PP P P R+ PG + D + LP T + P P Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDG--LQGQPGLPGPTGEKGSKGEPGLPGPP----- 952 Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGP 1102 G L+ S+ E+ E P PG G +G QG Sbjct: 953 -GPMDPNLL---------------GSKGEKGEPGLPGIPGVSGPKGY----------QGL 986 Query: 1103 REDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLE-TGAAAREGGP 1161 D Q G G NP PG +PG P +G + G EG P Sbjct: 987 PGDPGQPGLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLD------FPQEAKEPETAEESAPDSTEFTE 1215 PS P P + ++ P + P EP P + Sbjct: 1045 G----PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP--GYPGNPGIKG 1098 Query: 1216 ALRSPPA-ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLL 1274 ++ P G GA +P P GTP P G + P G+ PG + Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPKGISGPPGNPGLPGEPGPV 1151 Query: 1275 GGPG--GTQAPVSHNSK------DPPARQPGEFLAP-VANPSSTACPKPSVLSSKISSFG 1325 GG G G P K PA Q GE P NP P LS + G Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPG---LSGQKGDGG 1208 Query: 1326 CDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSS 1385 G +P G+P K P + P + GP G LE P + PP Sbjct: 1209 L--PGIPGNP-GLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ-GPPGRPG 1264 Query: 1386 CLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASP-----PTLESSSLFPDLPVDRFDPPL 1440 G + P LP + G + E G P P L+ P L + P L Sbjct: 1265 FQGLPGPEG---PPGLPGN--GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1319 Query: 1441 YGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEE--VSPMLPSHFPDLSGGKVLSK 1498 G D GLP P K PS P + E + P P P SG ++ K Sbjct: 1320 NG---MKGDPGLPGVPGFPGMKG-PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1375 Query: 1499 --TCPPERTVVPGAAPSLPG 1516 PP PG LPG Sbjct: 1376 GDAGPPGIPGQPG-LKGLPG 1394 Score = 64.3 bits (155), Expect = 2e-09 Identities = 315/1313 (23%), Positives = 396/1313 (30%), Gaps = 207/1313 (15%) Query: 309 PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGA-AHSAP 365 P+G ++ + GP P + P LP + G PG G+ H G PG Sbjct: 73 PRGQKGDDGI-PGPPGPKGIRGPPG-LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130 Query: 366 RPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT 425 R F S P P GL GPP + PG +S PGP Sbjct: 131 RGFPGS---------PGFP-----GLQGPPGPPGIPGMKGEPGSIIMSS----LPGPKGN 172 Query: 426 ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLP-------- 477 PGPP + L PT P P P GP G P P + L Sbjct: 173 P-GYPGPPG--IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229 Query: 478 -----QSAPLPWPQVLPTARP----------------SPHGMEMLSRLPFPAGGPEWQGG 516 Q P P Q+ RP P G + P P GG + + G Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289 Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPG--AQPLFFGVAQPQVSPHG 574 QG G GK PG + + G P + G DPG +P G + Q G Sbjct: 290 EQGEPGKRGK-PG--------KDGENGQPGIPGLPG--DPGYPGEPGRDG-EKGQKGDTG 337 Query: 575 TPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634 P PP +V +P P T G T + E PG GP Sbjct: 338 PPG--PPGLV--------IPRPGT---GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL 384 Query: 635 FHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEG 694 PP G P P P + P + P P GL + L P P G Sbjct: 385 PGPP-GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLDGQPGAPGLPGPPGP-AG 441 Query: 695 PEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQLDVLLTCRQC-------DRNYSSLAAF 746 P + P P PP L + D TC C L Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501 Query: 747 LAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPA-DAHAGLLSHAKTFL-LAGDAQ 804 G + + G + GP GLP P AP P G TF + GD Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561 Query: 805 AEGKDDPLRTGFLPSLAATPFP--LPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDS 862 G P G LP L TP LP + + G NP + Sbjct: 562 ELG--SPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGI------TFKGERGPPGNPGLPG 612 Query: 863 SFIDVFADEEPS-GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDP-----QTPRPGDR 916 ++ P GP GP ++ AG + P +P DP Q +PG Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAG----NPGQPGIPGPKGDPGQTITQPGKPGLP 668 Query: 917 GCPAR----GRPKTRSLGLAPTEADAP-SQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971 G P R G P L P P S+G G L G G+ G Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRL 1030 GL E PP P P + PG P P R Sbjct: 729 TPGRIGL---------EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 1031 PPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRG 1090 P P R G G + + Q + + PP PG G+ G Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839 Query: 1091 EKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL 1150 E P D P P R G GAP P P GS PG++ + P Sbjct: 840 GIPGEKGDPGPPGLDVPGPP--GERGSPGIPGAP-GPIGPPGSPGLPGKAGASGFPGTKG 896 Query: 1151 ETGAAAREGG------PKCADRPSVAPKDPLQ----VPTNT-ETSEETRPSLDFPQEAKE 1199 E G G P + P + D LQ +P T E + P L P + Sbjct: 897 EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956 Query: 1200 P-------ETAEESAP-----DSTEFTEALRSPPAACAGEMGAS--PGLLIPEQP----- 1240 P E E P + + L P G+ G S PGL P P Sbjct: 957 PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP----GQPGLSGQPGLPGPPGPKGNPG 1012 Query: 1241 -PPSRHDTGTPKPSGSLAN---TAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQ- 1295 P G P G++ + P G PG + G PG P K P Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072 Query: 1296 ---PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPH 1352 PG P P P + + DP G P G P AK P P Sbjct: 1073 IGLPG-LPGPKGEPGLPGYPGNPGIKGSVG----DP-GLPGLP-GTPGAKGQPGLPGFPG 1125 Query: 1353 SELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETE 1412 + GPK ++G PP + + G G P P PPG + + Sbjct: 1126 TPGPPGPKGISG---------------PPGNPGLPGEPGPVGGGGHPGQP-GPPG-EKGK 1168 Query: 1413 PGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANR-DSGLPFACADPPQKTVPSDPPYP 1471 PG+ P PP LS + D GLP +P +P + Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228 Query: 1472 SFLLLEEVSPMLPSHFPDLSGGK-VLSKTCPPERTVV-----PGAAPSLPGKG 1518 F ++ S P L G K PP R P P LPG G Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNG 1281 Score = 59.3 bits (142), Expect = 7e-08 Identities = 120/461 (26%), Positives = 144/461 (31%), Gaps = 88/461 (19%) Query: 20 PRQVASSPGHPSQPPLEDNT--PATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPS 77 P+ PG+P P ++ + P G A GQ P G PP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP---------GTPGPPG 1131 Query: 78 LRG-QAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDET 136 +G P PG G P G P + G P Q I G A + +P Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK--GKPGQDGIPGPAGQKGEPG---Q 1186 Query: 137 PENPQLEAAQLPEVDTPQGPG--TGAPLRPGLPRTEAQPAAEELGFHRC--FQEPPSSFT 192 P LP + +G G G P PGLP + +P GFH Q PP Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP-----GFHGFPGVQGPPG--- 1238 Query: 193 STNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVP- 251 P +P P GP + G P P P +Q PP PG N G+ Sbjct: 1239 ------PPGSPGPALEGPKGNPG--PQGPPGRPGFQGLPGPEGPPG----LPG-NGGIKG 1285 Query: 252 ----PAEPE-PIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAF 306 P +P P G + P G+ P L+G P V G GP Sbjct: 1286 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV-- 1343 Query: 307 HQPQGAWPEEAVGT-GPAYPLPTQPAPSPLPCY---QGQPGGLNRHSDLSGALSSPGAAH 362 P A PE G GP P P P PS P G+ L G L P Sbjct: 1344 --PGSAGPEGEPGLIGPPGP-PGLPGPSGQSIIIKGDAGPPGIPGQPGLKG-LPGPQGPQ 1399 Query: 363 SAPRPFSDSLHKSLTKILPERPPSAQ-----DGLGSTRGPPSSLPQRHFPGQAYRAS--- 414 P P P P DG G +G P PGQ Sbjct: 1400 GLPGPTG-----------PPGDPGRNGLPGFDGAGGRKGDPG------LPGQPGTRGLDG 1442 Query: 415 -----GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT 450 G+ PGPP T A G R Q D P T Sbjct: 1443 PPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1483 Score = 52.0 bits (123), Expect = 1e-05 Identities = 117/458 (25%), Positives = 144/458 (31%), Gaps = 74/458 (16%) Query: 3425 VRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLC 3484 + +PG PG L G P + V +PG PG+ P G E +P + Sbjct: 659 ITQPGKPG-----LPGN-PGRDGDVGLPGDPGLPGQPGLP--GIPGSKGEPGIPGI---- 706 Query: 3485 SEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALD 3544 P KG+P P P T G E P P P P AL G L Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP-GFALPGPPGPPGLP 765 Query: 3545 G---ALERPENEASPGSPGPLLQQALPLGASLPRP----GARGQDAEGKRAPLVFSGKRR 3597 G AL + PG PGP + L LP P G GQ L G + Sbjct: 766 GFKGALGPKGDRGFPGPPGPPGRTGLD---GLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822 Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSA 3657 PG G P H + EK + GP G +GS P Sbjct: 823 PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG--ERGSPGIPG----------- 869 Query: 3658 ASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717 A P P P KA S PG T+ M P PGP S PG K Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPG-----TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 3718 GGSQPQPA-------SGQLQSETATTPAKPSFPS--------RSPAPERLPARAQAKSCT 3762 G Q QP G P P P+ P +P + K Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 3763 KGPREAGEQGPHGSLG----PKEKGESSTKRKKGQVPGPARSESVGSFG-RAPSAPDKPP 3817 P + G+ G G G P KG + G + P ++G G P + PP Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 PS V P P P + K +PG Sbjct: 1045 -------GPSGV------PGQPGSPGLPGQKGDKGDPG 1069 Score = 51.6 bits (122), Expect = 2e-05 Identities = 170/687 (24%), Positives = 226/687 (32%), Gaps = 102/687 (14%) Query: 871 EEPSGPRGPSSGHPLKSKAGVTPES-KAPPPLPAATPDPQTP-RPGDRGCPA-RGRPKTR 927 E P GPRG + G P+ + PP LP P P PG G P +G P Sbjct: 68 EGPPGPRGQKGDDGIPGPPG--PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIP--- 122 Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR-PRRNDGL 986 G T+ + G G Q G G G S L P+ N G Sbjct: 123 --GCNGTKGERGFPGSPGFPGLQ-----GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY 175 Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046 P + T PG P P P + + P+ K G Sbjct: 176 PGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235 Query: 1047 GKELILKIVQQKNRLREYDFASESE--EDEQPPPRGPGFRGRRG--RGEKRKEVELTQGP 1102 G + ++ R + +F + ++ PP PG RG G GEK ++ E Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----- 290 Query: 1103 REDEPQKPRKAARQ-EAGGDGAPANPEEPGGSRPG-PGRSPQARGPSRSLETGAAAREG- 1159 + EP K K + E G G P P +PG PG PGR + + +TG G Sbjct: 291 -QGEPGKRGKPGKDGENGQPGIPGLPGDPG--YPGEPGRDGE---KGQKGDTGPPGPPGL 344 Query: 1160 -GPKCADRPSVAPKDPLQVP-TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217 P+ ++ K + +P E E P + P P A P Sbjct: 345 VIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG------- 397 Query: 1218 RSPPAACAGEMG-----ASPGLLIPEQP-----PPSRHDTGTPKPSG-------SLANTA 1260 P GE G PG+ IP P P + G P P+G + Sbjct: 398 ---PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454 Query: 1261 PHGSSPTPGVGSLLGGPG--GTQAPVSHN----SKDPPARQPGEFLAPVANPSSTACPKP 1314 P G +PG L G G G + N P QPG P P S P Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP-GPPGSLGFPGQ 513 Query: 1315 SVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL-FLGPKDLAGCFLEELHPK 1373 + + G P G P G P A P P L F G K G EL Sbjct: 514 KGEKGQAGATG--PKGLPGIP-GAPGAPGFPGSKGEPGDILTFPGMKGDKG----EL-GS 565 Query: 1374 PSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPG--TAETEPGRAASPPTLESSSLFPDL 1431 P A P + G+D P P+ PG T + E G +P P L Sbjct: 566 PGAPGLPGLPGT----PGQDGLPGLPG-PKGEPGGITFKGERGPPGNPG-------LPGL 613 Query: 1432 P--VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD 1489 P + PP +G + G+ +P Q +P P + + P LP + P Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN-PG 672 Query: 1490 LSGGKVLSKTCPPERTVVPGAAPSLPG 1516 G L P +PG P LPG Sbjct: 673 RDGDVGL-----PGDPGLPG-QPGLPG 693 Score = 47.8 bits (112), Expect = 2e-04 Identities = 113/463 (24%), Positives = 147/463 (31%), Gaps = 74/463 (15%) Query: 3432 GQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPST 3491 G K E P +PG PGP E P PRG + +P P Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGF-PGP-EGPPGPRGQK---GDDGIPGPPGPKGIRGPPG 96 Query: 3492 TKGWPETLERPV------DPVTHPIRGCELPSNHQECPP----PSLS--PFPAALADGRG 3539 G+P T P P I GC + P P L P P + +G Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-------------RPGARGQDAEGK 3586 + P + +PG PGP Q LP +P PG G Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 3587 RAPLVFSGKRRAPGARGRCAP-----DHFQEDHLLQKEKEVSSSHMVSEGGPRG-TFHKG 3640 L F G + G +G P ++ + E + + + GP G +G Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 3641 SATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA-----PGELARGTENGMKPAT 3695 P G + ++ K K + + + L PGE R E G K T Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT 336 Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755 PGP G PRPGT G + L E + FP P LP Sbjct: 337 --GPPGP--PGLVIPRPGTGITIGEKGNIGLPGLPGE----KGERGFPG-IQGPPGLP-- 385 Query: 3756 AQAKSCTKGPREAGEQGPHGSLG-PKEKGESSTKRKKG-QVPGPARSESVGSFGRAPSAP 3813 GP A GP G G P E+G+ + G +PGP + P AP Sbjct: 386 --------GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG------QPGAP 431 Query: 3814 DKP-PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 P P P P +P P P PP S K G Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGP-----PGPPGSPGDKGLQG 469 Score = 45.8 bits (107), Expect = 8e-04 Identities = 119/518 (22%), Positives = 164/518 (31%), Gaps = 84/518 (16%) Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLP 3478 P ++G+ PG PGQ + + LP PG PG PP G + + P Sbjct: 980 PKGYQGL--PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP--GLKGTIGDMGFP 1035 Query: 3479 ALLHLCSEVAPSTTKGWPETLERPV------DPVTHPIRGCELPSNHQECPPPSLSPFPA 3532 + PS G P + P DP I LP E P L +P Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE---PGLPGYP- 1091 Query: 3533 ALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG-------QDAE 3584 G+ + G++ P PG+PG Q LP P PG +G Sbjct: 1092 ------GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145 Query: 3585 GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATK 3644 G+ P+ G PG G E ++ + E G G + G Sbjct: 1146 GEPGPVGGGGHPGQPGPPG--------EKGKPGQDGIPGPAGQKGEPGQPGFGNPG---- 1193 Query: 3645 PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSS 3704 P G S + P P +P PG G P P PGP+ Sbjct: 1194 PPGLPGLSGQKGDGGLPG----IPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPAL 1247 Query: 3705 QG-SGSPRP----------GTKTGGGSQPQPASGQLQSETATTPAKPSFP--------SR 3745 +G G+P P G G P +G ++ E P +P P Sbjct: 1248 EGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKG-NPGQPGLPGLPGLKGDQG 1306 Query: 3746 SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK-EKGESSTKRKKGQV--------PG 3796 P + P R P G G G GP G + + + G + PG Sbjct: 1307 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG 1366 Query: 3797 PA-RSESVGSFGRAPSAPDKP--PRTPRKQATPSRVLPTKP--KPNSQNKPRPPPSEQRK 3851 P+ +S + P P +P P Q PT P P P + RK Sbjct: 1367 PSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRK 1426 Query: 3852 AEPGHTQRKDRLGKAFPQGRPLLR----PPKRGTAVHG 3885 +PG + G P G L+ PP + HG Sbjct: 1427 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHG 1464 Score = 44.7 bits (104), Expect = 0.002 Identities = 115/475 (24%), Positives = 140/475 (29%), Gaps = 62/475 (13%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG PG + LP PG GE PP P L L + Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN-----------PGLPGLPGNI 617 Query: 3488 APSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546 P G+ P PV I+G P P P G+ L G Sbjct: 618 GPMGPPGF-----GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP--GLPGN 670 Query: 3547 LERPENEASPGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF---SGKRRAPGAR 3602 R + PG PG Q LP + S PG G G P F G APG Sbjct: 671 PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730 Query: 3603 GRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS 3662 GR + K + GP G A P G DR P Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPG 784 Query: 3663 ----------KALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP 3712 K V P G + P L G P P PGP Q P Sbjct: 785 PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG--PPGPPGIPGPIGQPGLHGIP 842 Query: 3713 GTKTGGGSQPQPASGQL-QSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ 3771 G K G G + + P P P P LP +A A E G Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMM 901 Query: 3772 GPHGSLGPKE----------KGESSTKRKKGQVPGPARSESVGSFGR----APSAPDKPP 3817 GP G GP KG+ + + G +PGP + GS G P P P Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEK--GSKGEPGLPGPPGPMDPN 958 Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 K LP P + + P + +PG + + G P+G P Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLPGPPGPKGNP 1011 Score = 43.5 bits (101), Expect = 0.004 Identities = 199/866 (22%), Positives = 253/866 (29%), Gaps = 161/866 (18%) Query: 1752 PGTADQPHR-GAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGR 1810 PG QP G P P P + + ++ G PP G+ QG + Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-------GSPGDKGLQGEQGVK 474 Query: 1811 A----------GGHLHPTAGRPGFEGNEFAPA-----------GASSLTAPRGREAWLVP 1849 G + G+PG G P G + T P+G L Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG----LPG 530 Query: 1850 VPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNP 1909 +P P + P L PG K + G G L +P + Sbjct: 531 IPGA-------PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583 Query: 1910 SGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGT 1969 GL G E G + +G PG + LP G +G G G +G EK Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG-PMGPPGFGPPGPVG--EKGIQGVA 640 Query: 1970 ANQLQPENGVSPGGTDNHASVNASPKTALTG--PTEGAVLLEKCKGSRAAMSLQ----EE 2023 N QP G+ D ++ K L G +G V L G L + Sbjct: 641 GNPGQP--GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698 Query: 2024 AEP------TPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077 EP P PP P G+ G TP R GL P G P P Sbjct: 699 GEPGIPGIGLPGPPGPK------GFPGIPGPPGAPG-TPGRI---GLEGPPGPPG-FPGP 747 Query: 2078 SVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137 G+ P P +P G L P +G G PPGP Sbjct: 748 K-GEPGFALPGPPGPPGLPGFKGAL-------GPKGDRGFPG-----------PPGP--- 785 Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDP 2197 P L+ G + + P+ PP L G +QG P P Sbjct: 786 ----PGRTGLDGLPGPKGDVGPNGQPGPMGPP-----------GLPGIGVQGPPGPPGIP 830 Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257 P G P L +P PG SP + GA P + Sbjct: 831 G--PIGQPGLHGIPGEKGDPGPPGLDVP---------GPPGERGSPGIPGAPGPIGPPGS 879 Query: 2258 TGL-----SSTPTGDEAQAG-RGLPGPD-----PQSRGAPPHTNPDRMPRGHSSYSPSNT 2306 GL +S G + + G G PGP P G P D + P+ Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939 Query: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKE-----PEDPGTPETGRSG 2361 G P +P L G L G G S + P DPG P G SG Sbjct: 940 KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP--GLSG 997 Query: 2362 ATKMPRVTCPSTGLGL----GRTTAP--SSTASDFQSDSPQSHRNASHQTPQGDPLGP-Q 2414 +P P GL G P T D PQ P G P P Sbjct: 998 QPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP--PGPSGVPGQPGS 1055 Query: 2415 DLKQRSRGYKKKPASTENGQWKGQAPHG-------PVTCEVCAASFRSG-PGLSRHKARK 2466 +G K P + G P G P + + G PGL K Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115 Query: 2467 HRP----HPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVT 2522 +P PG P P P + L + P H G+ P +G P Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH--PGQPGPPGEKGKPGQDG 1173 Query: 2523 QPPPAQGSKEVLRAPGSPHSQQLHPP 2548 P PA E PG P PP Sbjct: 1174 IPGPAGQKGE----PGQPGFGNPGPP 1195 Score = 43.5 bits (101), Expect = 0.004 Identities = 236/1003 (23%), Positives = 303/1003 (30%), Gaps = 218/1003 (21%) Query: 1684 GDSRPPQD-VCLPEPSKQPGPQLDAG-------------SLAKC---------------- 1713 G PP D +C P P PG D G + C Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500 Query: 1714 --SPDQELSFP--KNKEAASSQESEDSLRLLPCE-----------QRGGFLPEPG-TADQ 1757 P L FP K ++ + L +P + G L PG D+ Sbjct: 501 LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDK 560 Query: 1758 PHRGAPA----PEAFGSPAVHLAPDL----------AFQGDGAPPLDATWPFGASPSHAA 1803 G+P P G+P P L F+G+ PP + P P + Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP--GLPGNIG 618 Query: 1804 QGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVP-SPACVSNTHPS 1862 G G G G +G P G + P+G + P P N P Sbjct: 619 ---PMGPPGFGPPGPVGEKGIQGVAGNP-GQPGIPGPKGDPGQTITQPGKPGLPGN--PG 672 Query: 1863 RRSQ-----DPAL--------------SPPIRQLQLPGPGVAKSKDGILGLQEL--TP-- 1899 R DP L P I + LPGP K GI G TP Sbjct: 673 RDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGR 732 Query: 1900 -AAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEAD-GHWGL 1957 + PP P G G E G GP G PG LP G LG + D G G Sbjct: 733 IGLEGPP--GPPGFPGPKGEPGFALPGP-PGPPG------LPGFKG-ALGPKGDRGFPGP 782 Query: 1958 LGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGP-----------TEGAV 2006 G +T G P+ V P G P + GP G Sbjct: 783 PGPPGRTGLDGLPG---PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839 Query: 2007 LLEKCKGSRAAMSLQEEAEP-------TPSPPSPNRESLALALTAAHSRSGSEGRTPERA 2059 + KG L P P P P + L SG G E Sbjct: 840 GIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899 Query: 2060 --SSPGLNKPLLATGDSPAPSV-GDLAACA----PSPT---SAAHMPCSLGPLPREDPLT 2109 PG PL G S P + GD P PT + P GP DP Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959 Query: 2110 SPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAP- 2168 S+ + G G LP P P G Q L P L G+ G + +P P Sbjct: 960 LGSKGEKGEPG-LPGIPGVSGPKGYQGLPG-DPGQPGLSGQPGLPG--PPGPKGNPGLPG 1015 Query: 2169 -PSLTTSPCDPKEALAGCLLQG----EGSPLEDPSSWP--PGSVSAVTCTHSGDTPKDST 2221 P L P K + G EG P PS P PGS P S+ Sbjct: 1016 QPGL-IGPPGLKGTIGDMGFPGPQGVEGPP--GPSGVPGQPGSPGLPGQKGDKGDPGISS 1072 Query: 2222 LRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQ 2281 + +P + PG +P + G+V GL P A+ GLPG P Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKGSVGD------PGLPGLPGTPGAKGQPGLPG-FPG 1125 Query: 2282 SRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGE 2341 + G P P+G S P N +P EP + G G GE Sbjct: 1126 TPGPPG-------PKGISG-PPGN------------PGLPGEPGPVGGGGHPGQPGPPGE 1165 Query: 2342 MGTSSK--------EPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSD 2393 G + + +PG P G G +P ++ GL P + Sbjct: 1166 KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL--PGIPGNPGLPGPKG 1223 Query: 2394 SPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKG-QAPHGPVTCEVCAAS 2452 P H Q P G P P + +G ++G P GP Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGP--------- 1274 Query: 2453 FRSGPGLSRHKARK-HRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERP 2511 PGL + K + +PG P P L Q PP + + G+ Sbjct: 1275 ----PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ---------GPPGLQGN--PGRPGL 1319 Query: 2512 NHSRGDPSHVTQPPPAQGSKEVLRAPGS--PHSQQ--LHPPSP 2550 N +GDP + P G K PGS P + + PP P Sbjct: 1320 NGMKGDPG-LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1361 Score = 40.4 bits (93), Expect = 0.035 Identities = 56/209 (26%), Positives = 69/209 (33%), Gaps = 18/209 (8%) Query: 3693 PATPKAKPGPSSQGSG---SPRPGTKTGGGSQPQPASGQLQSETATT----PAKPSFPSR 3745 P P PG + S PG K G P L T P P Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 3746 SPAPERLPA-RAQAKSCTKGPR-EAGEQGPHGSLGP-----KEKGESSTKRKKGQ--VPG 3796 P P LP + +GP+ E GEQG G GP ++K + +KG +PG Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 3797 PARSESVGSFGRAPSAPDKPPRTPRKQATPS-RVLPTKPKPNSQ-NKPRPPPSEQRKAEP 3854 P P +Q P R P K N Q P P EP Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324 Query: 3855 GHTQRKDRLGKAFPQGRPLLRPPKRGTAV 3883 G K + G P G P L P+ GT + Sbjct: 325 GRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353 Score = 37.7 bits (86), Expect = 0.23 Identities = 50/197 (25%), Positives = 62/197 (31%), Gaps = 35/197 (17%) Query: 489 PTARPSPHGMEMLSRLPFPAG-----GPEWQGGSQGALGTAGK-----TPGPREKLPAVR 538 P P P G + +P P G GP G G G G PGP + +P Sbjct: 67 PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP-QGIPGCN 125 Query: 539 SSQG-----GSPALFTYNGMTDPGAQPLFFG-----VAQPQVSPHGTPSLPPPRVVGASP 588 ++G GSP G P P G + P G P P P + P Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP 185 Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSA--FFHPPTHPQETGS 646 + +P P P P P LPGP G F P E G Sbjct: 186 GPTGIPGPIGPPG-------PPGLMGPPGPPG----LPGPKGNMGLNFQGPKGEKGEQGL 234 Query: 647 PFPSPEPPHSLPTHYQP 663 P P PP + +P Sbjct: 235 QGP-PGPPGQISEQKRP 250 Score = 37.0 bits (84), Expect = 0.39 Identities = 169/712 (23%), Positives = 217/712 (30%), Gaps = 136/712 (19%) Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASA 3265 P P+ G R G PG P + PG P P + DGA P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH-DGAPGPQGIPG 123 Query: 3266 T--ALADAGSPGPP-----RTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCG--- 3315 + G PG P + P P P GEP + + + P + + G Sbjct: 124 CNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKGNPGYPGPPG 180 Query: 3316 -KRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLY 3374 + P P + + P + P P + G + + G G LQ P Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240 Query: 3375 ACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGAP--G 3432 ++ I + F K +Q L G R P G+R P P G Sbjct: 241 PGQISEQKRPI----------DVEFQKGDQ-------GLPGDRGPPGPPGIRGPPGPPGG 283 Query: 3433 QKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTT 3492 +K E P KR + PG+D E P + Sbjct: 284 EKGEKGEQGEPGKRGK---------PGKD-----------GENGQPGI------------ 311 Query: 3493 KGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA--LADGRGDCALDGAL--- 3547 G P P +P +G + PP + P P +G+ L G Sbjct: 312 PGLPGDPGYPGEPGRDGEKG-QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370 Query: 3548 -ER--PENEASPGSPGPLLQQALPLGASLPR--PGARGQDAEGKRAPLVFS-----GKRR 3597 ER P + PG PGP A +G P PG RGQ +G P S G Sbjct: 371 GERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQ--KGDEGPPGISIPGPPGLDG 426 Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR-- 3655 PGA G P H + S + E GP G G Q D+ Sbjct: 427 QPGAPGLPGPPGPAGPH-------IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479 Query: 3656 -------SAASTPSKALKFPVHPRKAVGSLA----PGELARGTENGMK--PATPKAKPGP 3702 + S P P P GSL GE + G K P P A P Sbjct: 480 TCFNCIGTGISGPPGQPGLPGLPGPP-GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538 Query: 3703 SSQGS-GSPR-----PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756 GS G P PG K G P + L T P + P P P+ P Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGL-PGPKGEPGGI 596 Query: 3757 QAKSCTKGPR----------EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSF 3806 K +GP G GP G P GE + G P G Sbjct: 597 TFKG-ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655 Query: 3807 GRAPSAPDKP--PRTPRKQATPSRVLPTKP-KPNSQNKPRPPPSEQRKAEPG 3855 G+ + P KP P P + LP P P P P S K EPG Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVG--LPGDPGLPGQPGLPGIPGS---KGEPG 702 Score = 36.6 bits (83), Expect = 0.50 Identities = 60/248 (24%), Positives = 80/248 (32%), Gaps = 28/248 (11%) Query: 1689 PQDVCLPEPSKQPG----PQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQ 1744 P + LP P +PG P + SP L PK + LP + Sbjct: 1213 PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPE 1272 Query: 1745 RGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQ 1804 LP G + +G P G P + P L +GD PP G + Sbjct: 1273 GPPGLPGNGGI-KGEKGNP-----GQPGLPGLPGL--KGDQGPP-------GLQGNPGRP 1317 Query: 1805 GHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRR 1864 G + + L G PG +G P+G P G E L+ P P + P Sbjct: 1318 GLNGMKGDPGLPGVPGFPGMKG----PSGVPGSAGPEG-EPGLIGPPGPPGL----PGPS 1368 Query: 1865 SQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVAC 1924 Q + +PG K G G Q L P +GL G GG+ Sbjct: 1369 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1428 Query: 1925 GPAQGSPG 1932 G PG Sbjct: 1429 PGLPGQPG 1436 Score = 36.2 bits (82), Expect = 0.66 Identities = 105/488 (21%), Positives = 148/488 (30%), Gaps = 82/488 (16%) Query: 2101 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLAC-----------------SPA 2143 P P+ P + ++ + G G P P + PPGP + +P Sbjct: 116 PGPQGIPGCNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPG 174 Query: 2144 WAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP----KEALAGCLLQG-EGSPLEDPS 2198 + G+ T P PP L P P + G QG +G E Sbjct: 175 YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGL 234 Query: 2199 SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRAT 2258 PPG ++ + + + + L G P + G P + Sbjct: 235 QGPPGPPGQIS-------EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287 Query: 2259 GLSSTPTGDEAQAGR----------GLPGPDPQSRGAPPH---------TNPDRMPRGHS 2299 G + G+ GLPG DP G P T P P G Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPP-GLV 345 Query: 2300 SYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDP-GTP-ET 2357 P +G + + +P E G P L G G + P P G P E Sbjct: 346 IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405 Query: 2358 GRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLK 2417 G+ G P ++ P G+ AP + H S + + P GP Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGP---HIPPSDEICEPGPPGPPG-- 460 Query: 2418 QRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGP----GLSRHKARKHRPHPGA 2473 S G K KG TC C + SGP GL PG Sbjct: 461 --SPGDKGLQGEQGVKGDKGD------TCFNCIGTGISGPPGQPGL-----------PGL 501 Query: 2474 PAEPSPAALPAQQPLEPLAQKCQPPRKKS-HRVSGKERPNHSRGDPSHVTQPPPAQGSKE 2532 P P P Q+ + A P G S+G+P + P +G K Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561 Query: 2533 VLRAPGSP 2540 L +PG+P Sbjct: 562 ELGSPGAP 569 Score = 34.3 bits (77), Expect = 2.5 Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 16/133 (12%) Query: 3183 LGDLPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240 L LPG G +G + + P PK G G PG G + PG Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 3241 ERAKPRARSTPS--------NPDGAATPDSASATALA----DAGSPGPPRT--TPSPSPD 3286 E+ KP P G P L+ D G PG P P P + Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224 Query: 3287 PWAGGEPLLQATP 3299 P G P +Q P Sbjct: 1225 PGFHGFPGVQGPP 1237 Score = 33.9 bits (76), Expect = 3.3 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 16/121 (13%) Query: 3186 LPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAKKDS 3238 LPG GL G + + + P P+ G G PG P G +G+ S Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072 Query: 3239 PGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQAT 3298 G P + P P P ++ D G PG P T P A G+P L Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKG--SVGDPGLPGLPGT-------PGAKGQPGLPGF 1123 Query: 3299 P 3299 P Sbjct: 1124 P 1124 Score = 33.1 bits (74), Expect = 5.6 Identities = 22/55 (40%), Positives = 22/55 (40%), Gaps = 3/55 (5%) Query: 1232 PGLLIPEQPPPSRH---DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283 PG PE PP R D G P P G P G PG L G PG AP Sbjct: 62 PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 99.4 bits (246), Expect = 6e-20 Identities = 355/1598 (22%), Positives = 500/1598 (31%), Gaps = 249/1598 (15%) Query: 80 GQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPEN 139 G S G P P G P P G G PP G + P Sbjct: 2 GNEVSLEGGAGDGPLPPGGAGPGPGPG--PGPGAGKPPSAPAGG----------GQLPAA 49 Query: 140 PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPP--SSFTSTNYT 197 + +P V P GPG G PG P E LG R P +S T+ + Sbjct: 50 GAARSTAVPPVPGP-GPGPGPGPGPGSTSRRLDPK-EPLGNQRAASPTPKQASATTPGHE 107 Query: 198 SPSATPRPPAPGPPQSRGTSP---LQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAE 254 SP T A GP P LQ S Q SG S P + + VP Sbjct: 108 SPRETR---AQGPAGQEADGPRRTLQVDS--RTQRSGRSPSVSPDRGSTPTSPYSVPQIA 162 Query: 255 PEP------IPKGSRPGGSPRGVSFQFPFPALH------GASTKPFPADVAGHAFTNGPL 302 P P I K S +P +F + G + P V N + Sbjct: 163 PLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQM 222 Query: 303 VFAFHQPQGAWPEE-------AVGTGPAYPLPTQPAPSPLPCYQGQPGGL---NRHSDLS 352 A P + PA+ QP P PGG +R ++ + Sbjct: 223 QRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETA 282 Query: 353 GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYR 412 A S PG A +A P + ++ P+ P + R P P + Sbjct: 283 RATSVPGPAQAAAPP-------EVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAG 335 Query: 413 ASGVDTSPGPPDTELAAPGPP---PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG--- 466 + + +L G A P A P P T + FN Sbjct: 336 LGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQP--APSKGTPKIVFNDASK 393 Query: 467 QPSPGQRLCLPQSAPLPWPQVLPTARPSP-HGMEMLSRLPFPAGGPEWQGGSQGALGTAG 525 + P P P P + P AR P G L + + Q A A Sbjct: 394 EAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAA 453 Query: 526 KT---PGPREKLPAVRSSQG-GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH-------- 573 K P R P ++ GS + YN T Q P +PH Sbjct: 454 KPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNP--TPHLVEKTEWL 511 Query: 574 --------------GTPS-LPPP-----------RVVGASPSESPLPSPATNTAGSTCSS 607 G P+ LPPP R G SP + P +G + Sbjct: 512 CLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAK 571 Query: 608 LSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAK 667 SP+S+ + S+ S PL S P+ QE + P+ P P P + Sbjct: 572 ASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKP------PPE 625 Query: 668 AFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQL 727 P PA G + TP PE +GG + PY + S S SL Sbjct: 626 TTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGG-EAEDLVGKPY-SQDASRSPQSLS-- 681 Query: 728 DVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAH 787 D YSS + + G++ + S G G P PP+ P++ H Sbjct: 682 ---------DTGYSSDGISSSQSEITGVVQQEVE--QLDSAGVTG-PHPPS----PSEIH 725 Query: 788 AGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEA 847 + S + L A + PL +G P L + + D +L+ ++ E Sbjct: 726 K-VGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEED 784 Query: 848 LNGMEY-----QSDNPEIDSSFIDV----FADEEPSGPRGPSSGHPLKSKAGVTPESKAP 898 + E+ Q D E F + ++ G P P A +T E Sbjct: 785 EDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMR 844 Query: 899 PPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKL----- 953 + + + D RG K + P PSQ ++L Sbjct: 845 RQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTG 904 Query: 954 FRKDLDSGGAAE---GSGSGGGG---------RASGLRPRRNDGLGERPPPR-PRRPRTQ 1000 + + L GG+AE GSG+ GG ++G D LG+ P P R P + Sbjct: 905 YEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELD-LGQGPDPSLDREPELE 963 Query: 1001 APGSRADPAPRV--PRAAALPEETRS---------------------SRRRRLPPRKDPR 1037 P R ++ LP T S SRR+RL K R Sbjct: 964 MESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQR 1023 Query: 1038 KRKARGGAWGKELILKIVQQKNRLREYDFASESE---EDEQPPPRGPGFRGRRGRGEKRK 1094 K + R I +++ E + E E E EQ R + RR + E R Sbjct: 1024 KARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELR- 1082 Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR-GPSRSLETG 1153 Q RE P + E D +P RS + PS SL++ Sbjct: 1083 ----AQRRRERSKTPPSNLSPIE---DASPTEELRQAAEMEELHRSSCSEYSPSPSLDSE 1135 Query: 1154 AAAREGGP----KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPD 1209 A A +GGP K ++ L PT T + T PS P ++AEE+ + Sbjct: 1136 AEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPL-----KSAEEAYEE 1190 Query: 1210 STEFTEALRSPPAACAGEMGASPGLLIPEQPPPSR------HDTGTPKPSGSLANTAPHG 1263 E L+ AG G G P QP R + T + G A A G Sbjct: 1191 MMRKAELLQRQQGQAAGARGPHGG---PSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEG 1247 Query: 1264 SSPTPGVG---SLLGGPGGTQAPVSHNSKD---------------------PPARQPGEF 1299 + + G +L +S+D P +Q G Sbjct: 1248 TPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGP 1307 Query: 1300 LAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGP 1359 L P +P+ A P S+ SS D +G P V V + + P +L P Sbjct: 1308 LTPGTSPTQLAAPVS--FSTPTSS---DSSGGRVIP-DVRVTQHFAKETQDP-LKLHSSP 1360 Query: 1360 KDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLP---RSPPGTAETEPGRA 1416 + E P P ++ C G G + P P P + T Sbjct: 1361 ASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYG 1420 Query: 1417 ASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLL 1476 SP T S DLP + L + A R+ P + +D T Y F Sbjct: 1421 HSPTTANYGSQTEDLP--QAPSGLAAAGRAAREK--PLSASDGEGGTPQPSRAYSYFASS 1476 Query: 1477 E-EVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPS 1513 +SP PS P S GK+ + T P AP+ Sbjct: 1477 SPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPA 1514 Score = 55.5 bits (132), Expect = 1e-06 Identities = 175/788 (22%), Positives = 258/788 (32%), Gaps = 155/788 (19%) Query: 1783 GDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAP-R 1841 GDG P P GA P G G P AG+P APAG L A Sbjct: 12 GDGPLP-----PGGAGPG---PGPGPG-------PGAGKP-----PSAPAGGGQLPAAGA 51 Query: 1842 GREAWLVPVPSPACVSNTHPSRRSQDPALSP--PIRQLQLPGPGVAKSKDGILGLQELTP 1899 R + PVP P P S L P P+ + P ++ TP Sbjct: 52 ARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQAS-------ATTP 104 Query: 1900 AAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLG 1959 +SP A GPA G EADG L Sbjct: 105 GHESPRETR--------------AQGPA--------------------GQEADGPRRTLQ 130 Query: 1960 QAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMS 2019 +TQ G + + P+ G +P S + P+ A P + L CK S Sbjct: 131 VDSRTQRSGRSPSVSPDRGSTP------TSPYSVPQIA---PLPSSTLCPICKTS----- 176 Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSE-GRTPERASSPGLN--KPLLATGDSPA 2076 + TPS P+ N T H++ ++ G P +P L K L Sbjct: 177 ---DLTSTPSQPNFN------TCTQCHNKVCNQCGFNP----NPHLTQVKEWLCLNCQMQ 223 Query: 2077 PSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQ 2136 ++G AP S + P P SP++ G P R P GPQ Sbjct: 224 RALGMDMTTAPRSKSQQQLHS-----PALSPAHSPAKQPLG----KPDQERSRGPGGPQ- 273 Query: 2137 LLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP---KEALAGCLLQGEGSP 2193 +A+ +AT+ G + P SP P K + A +P Sbjct: 274 --------PGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAP 325 Query: 2194 LEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATS--PPLAGAVSP 2251 + ++ P G + A T G T K L ++ L A + P +P Sbjct: 326 AKSATAVPAG-LGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTP 384 Query: 2252 SVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAP-----PHTNPDRMPRGHSSYSPSNT 2306 + + P + G PGP P ++ P P + P +P+ + SP + Sbjct: 385 KIVFNDASKEAGPKPLGSGPG---PGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKH- 440 Query: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMP 2366 G E QA + +P T+ P C + E+ SK P + T T R Sbjct: 441 ---GRAEHQAASKAAAKPKTMPKERAICPLC-QAELNVGSKSPANYNTCTTCR------- 489 Query: 2367 RVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKK 2426 C G T +++ + Q+ R + PL P +Q G + Sbjct: 490 LQVCNLCGF---NPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHR 546 Query: 2427 PASTENGQWKGQ----APHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAAL 2482 + T + KG P GP+ + S ++ P S+ + P +EPS Sbjct: 547 ASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK---ASPQAKPLRASEPSKTPS 603 Query: 2483 PAQQPLEPLAQKCQ-----PPRKKSHRVSGKERPNHSRGDPSH--VTQPPPAQGSKEVLR 2535 Q+ + K + PP + K + R +P+ V P A E Sbjct: 604 SVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAED 663 Query: 2536 APGSPHSQ 2543 G P+SQ Sbjct: 664 LVGKPYSQ 671 Score = 55.1 bits (131), Expect = 1e-06 Identities = 334/1501 (22%), Positives = 485/1501 (32%), Gaps = 239/1501 (15%) Query: 54 QAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAE 113 +A M++ A PR +L P+L SP P + PL P + R Sbjct: 224 RALGMDMTTA-PRSKSQQQLHSPAL-------------SPAHSPAKQPLGKPDQERSRGP 269 Query: 114 GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRT-EAQ 172 G P SR T T +AA PEV G + P +P P T E + Sbjct: 270 GGPQP-------GSRQAETARATSVPGPAQAAAPPEV----GRVSPQPPQPTKPSTAEPR 318 Query: 173 PAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGA 232 P A E + P+ +T T T + G S L PE G Sbjct: 319 PPAGEAPA-KSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLM-SVQPEADTQGQ 376 Query: 233 DSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADV 292 PA P F E P P GS PG P GA T+P Sbjct: 377 ----PAPSKGTPKIVFNDASKEAGPKPLGSGPGPGP-----------APGAKTEPGARMG 421 Query: 293 AGHAFTNGPLVFAFHQPQ-GAWPEEAVGTGPAYP--LPTQPAPSPL---PCYQGQPGGLN 346 G P P+ G +A A P +P + A PL G N Sbjct: 422 PGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPAN 481 Query: 347 RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDG-LGSTRGPPSSLPQRH 405 ++ + L P P + K+ L + +G LG P Q+ Sbjct: 482 YNTCTTCRLQVCNLCGFNPTP--HLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539 Query: 406 FPGQAYRASGVDTSPGPPDTELAAP-GPPPARLPQLWDPTAAPYP---TPPGGPLAATRS 461 G +RASG L P GP PA+ L A+P P +P PL A+ Sbjct: 540 PVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPL-STKASPLPSKASPQAKPLRASEP 598 Query: 462 MFFNGQPSPGQ--RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRL-------PFPAGGPE 512 + PS Q + +P A P P+ P P+P ++ S + P PE Sbjct: 599 ---SKTPSSVQEKKTRVPTKAE-PMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPE 654 Query: 513 WQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP 572 G G A G A RS Q S ++ +G++ +Q GV Q +V Sbjct: 655 APKG-----GEAEDLVGKPYSQDASRSPQSLSDTGYSSDGIS--SSQSEITGVVQQEVE- 706 Query: 573 HGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPS 632 L V G P P+ + SS+ P+ + SE S+ Sbjct: 707 ----QLDSAGVTGPHP-------PSPSEIHKVGSSMRPLLQAQGLAPSERSK-------- 747 Query: 633 AFFHPPTHPQETGSPFPSPEPPHSL---PTHYQPEPAKAFPFPADGLGAEGAFQCLEE-- 687 P +G+ + PHSL P + + D AE + ++ Sbjct: 748 --------PLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDT 799 Query: 688 --------TPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRN 739 + H+ E G G PP P L+ + +L + D Sbjct: 800 AESSDDFGSQLRHDYVEDSSEG--GLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNL 857 Query: 740 YSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP------RVPADAHAGLLSH 793 A GL AK G Q+ GP P P P R+P +A G + Sbjct: 858 EEDDTATSGR----GL----AKHGTQKG-GPRPRPEPSQEPAALPKRRLPHNATTG---Y 905 Query: 794 AKTFLLAGDAQAEGKDDPLRTGF----LPSLAATPFPLPASDLDMEDDAKLD---SLITE 846 + G A+A L+ G L +T DL D LD L E Sbjct: 906 EELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEME 965 Query: 847 ALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATP 906 +L G E S+ P+ +SG S + + +S + P Sbjct: 966 SLTGSPEDRSRGEHSSTL--------PASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLE 1017 Query: 907 DPQTPRPGDRGCPARGRPKTRSLG-LAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAE 965 + + R + + RS G L PT D+ S+ + R ++L ++ + E Sbjct: 1018 EAKQQR----------KARHRSHGPLLPTIEDS-SEEEELREEEEL---LREQEKMREVE 1063 Query: 966 GSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSR------ADPAPRVPRAAALP 1019 R++ + RR+ E + RR R++ P S A P + +AA + Sbjct: 1064 QQRI----RSTARKTRRDK---EELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEME 1116 Query: 1020 EETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPR 1079 E RSS P + +A G G + K + N S +E P Sbjct: 1117 ELHRSSCSEYSPSPSLDSEAEALDG--GPSRLYKSGSEYNLPTFMSLYSPTE-----TPS 1169 Query: 1080 GPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGR 1139 G GR K E + R+ E + ++ Q AG G P +P G R Sbjct: 1170 GSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQG--QAAGARGPHGGPSQPTGPRGLGSF 1227 Query: 1140 SPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTN-TETSEETRPSLDFPQEAK 1198 Q + A EG P A + ++ LQ + + + L F ++ K Sbjct: 1228 EYQDTTDREYGQAAQPAAEGTP--ASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK 1285 Query: 1199 EPE---TAEESAPDSTEFTEALRSP---PAACAGEMG--------ASPGLLIPEQPPPSR 1244 + + AE + D + +P P A + +S G +IP+ Sbjct: 1286 KEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQH 1345 Query: 1245 HDTGTPKPSGSLANTAPHGSSPTPGVGSLLG-GPGGTQAPVSHNSKDPPARQPGEFLAPV 1303 T P L ++ SS + +G GPG P + PA P ++ P Sbjct: 1346 FAKETQDPL-KLHSSPASPSSASKEIGMPFSQGPG---TPATTAVAPCPAGLPRGYMTPA 1401 Query: 1304 ANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLA 1363 + S P P SS S+G P N Y S +L P LA Sbjct: 1402 SPAGSERSPSP---SSTAHSYGHSPTTAN---------------YGSQTEDLPQAPSGLA 1443 Query: 1364 GCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLE 1423 SA D + A S P P SP + PG+ T E Sbjct: 1444 AAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAE 1503 Query: 1424 SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPML 1483 S+ P P D P R G P Q T P L+ +E S Sbjct: 1504 FSTQTPS-PAPASDMP--------RSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEA 1554 Query: 1484 P 1484 P Sbjct: 1555 P 1555 Score = 50.4 bits (119), Expect = 3e-05 Identities = 75/322 (23%), Positives = 110/322 (34%), Gaps = 59/322 (18%) Query: 3588 APLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAG 3647 AP+ FS + + GR PD H ++ ++ H S P SA+K G Sbjct: 1319 APVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS-SPASP------SSASKEIG 1371 Query: 3648 CQSSSKDRSAAST-----PSKALKFPVHPRKAVGS-LAPGELARGTENGMKPAT------ 3695 S + A+T P+ + + P GS +P + G P T Sbjct: 1372 MPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQ 1431 Query: 3696 ----PKAKPGPSSQGSGSPRP--GTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAP 3749 P+A G ++ G + G G PQP+ +++ P PS PS SP Sbjct: 1432 TEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESP-- 1489 Query: 3750 ERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA 3809 T P G +GP+ E ST Q P PA + + R+ Sbjct: 1490 ------------TFSP---------GKMGPRATAEFST-----QTPSPAPASDM---PRS 1520 Query: 3810 PSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQ 3869 P AP P + TP R P+ P+ Q + P + R+ A Sbjct: 1521 PGAPTPSPMVAQGTQTPHR--PSTPRLVWQESSQEAPF-MVITLASDASSQTRMVHASAS 1577 Query: 3870 GRPLLRPPKRGTAVHGAEPAEP 3891 PL P + HG P Sbjct: 1578 TSPLCSPTETQPTTHGYSQTTP 1599 Score = 46.6 bits (109), Expect = 5e-04 Identities = 163/724 (22%), Positives = 230/724 (31%), Gaps = 123/724 (16%) Query: 3222 GSPGD---PWGQEGEAKKDSPGERAKPRARSTPSNPDGAAT-PDSASATALADAGSPGPP 3277 G GD P G G PG P A PS P G P + +A + A PGP Sbjct: 9 GGAGDGPLPPGGAGPGPGPGPG----PGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPG 64 Query: 3278 RTTPSPSPDPWAGG--------EPL-------------LQATPVHEACKDPSRDCHHCGK 3316 P P P P G EPL TP HE+ ++ +R G+ Sbjct: 65 ---PGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRE-TRAQGPAGQ 120 Query: 3317 RFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLYAC 3376 P +R L V S R R P V P+ G + P P+ C Sbjct: 121 EADGP---RRTLQVDS--RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPI--C 173 Query: 3377 ELCATVMRIIKKSF-ACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFR-------GVRRP 3428 + + +F C+ C+ + F+ N HL ++ G+ Sbjct: 174 KTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNP--NPHLTQVKEWLCLNCQMQRALGMDMT 231 Query: 3429 GAPGQKAR------ALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLH 3482 AP K++ AL ++ + P G P P GS A Sbjct: 232 TAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQP---------GSRQAETA 282 Query: 3483 LCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCA 3542 + V P + R P + PS + PP +P +A A G A Sbjct: 283 RATSVPGPAQAAAPPEVGRVSPQPPQPTK----PSTAEPRPPAGEAPAKSATAVPAGLGA 338 Query: 3543 LDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAP-LVFSGKRRAPGA 3601 + E + G LL QA L + P +GQ A K P +VF+ + G Sbjct: 339 TEQTQEGLTGKLF-GLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGP 397 Query: 3602 RGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTP 3661 + + K + M GP G+ K G S R+ Sbjct: 398 KPLGSGPG---PGPAPGAKTEPGARMGPGSGP------GALPKTGGTTSPKHGRAEHQAA 448 Query: 3662 SKALKFP--VHPRKAVGSLAPGELARGTE---NGMKPATPKAKPGPSSQGSGSPRPGTKT 3716 SKA P + +A+ L EL G++ N T + + + +P KT Sbjct: 449 SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKT 508 Query: 3717 GGGSQPQPASGQLQSETAT-TPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHG 3775 L+ TP P P+ P P RA S K + G QG Sbjct: 509 EWLCLNCQTKRLLEGSLGEPTPLPP--PTSQQPPVGAPHRASGTSPLK---QKGPQGLGQ 563 Query: 3776 SLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPK 3835 GP S K +P A ++ P +P +TP +PTK + Sbjct: 564 PSGPLPAKASPLSTKASPLPSKASPQA------KPLRASEPSKTPSSVQEKKTRVPTKAE 617 Query: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHR 3895 P P+PPP + P PK + V AEPA P Sbjct: 618 P----MPKPPP----------------------ETTPTPATPKVKSGVRRAEPATPVVKA 651 Query: 3896 TAEA 3899 EA Sbjct: 652 VPEA 655 Score = 46.2 bits (108), Expect = 6e-04 Identities = 99/391 (25%), Positives = 129/391 (32%), Gaps = 89/391 (22%) Query: 2324 PPTLQGAGPDSPACLEGEMGTSSKEPEDPG----TPETGRSGATKMPRVTCPSTGLGLGR 2379 PP G GP G + K P P P G + +T +P V P G G G Sbjct: 17 PPGGAGPGPGP-----GPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPG- 70 Query: 2380 TTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQA 2439 P ST+ P ++ A+ TP+ + G++ P T GQ Sbjct: 71 -PGPGSTSRRLDPKEPLGNQRAASPTPK-------QASATTPGHES-PRETRAQGPAGQE 121 Query: 2440 PHGPV-TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPP 2498 GP T +V + + RSG S R P SP ++P PL P + C P Sbjct: 122 ADGPRRTLQVDSRTQRSGRSPSVSPDRGSTP-------TSPYSVPQIAPL-PSSTLC-PI 172 Query: 2499 RKKSHRVSGKERPNHSRGDPSH--------VTQPPPAQGSKEVL---------------R 2535 K S S +PN + H P KE L Sbjct: 173 CKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTT 232 Query: 2536 APGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDS 2595 AP S QQLH P+ + K P K PDQ R Sbjct: 233 APRSKSQQQLHSPALSPAHSPAKQPLGK--PDQER------------------------- 265 Query: 2596 PSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEG 2655 S G + G + R S+ P A + R SP P+ + E Sbjct: 266 ---SRGPGGPQPGSRQAETARATSV-PGPAQAAAPPEVGRVSP----QPPQPTKPSTAEP 317 Query: 2656 GPEADGEQPPRLATLGPGVMEGAAETDQEAL 2686 P A GE P + AT P + GA E QE L Sbjct: 318 RPPA-GEAPAKSATAVPAGL-GATEQTQEGL 346 Score = 46.2 bits (108), Expect = 6e-04 Identities = 87/381 (22%), Positives = 121/381 (31%), Gaps = 64/381 (16%) Query: 2222 LRIPEDSRKEK-------LWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRG 2274 L ED +KEK + P + PL SP+ S TPT ++ GR Sbjct: 1278 LAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFS-TPTSSDSSGGRV 1336 Query: 2275 LPGPDPQSRGAPPHTNPDRMPRGHSS-YSPSNTAR---LGHREGQAVTAVPTEPPTLQGA 2330 +P A +P ++ HSS SPS+ ++ + +G A P G Sbjct: 1337 IPDVRVTQHFAKETQDPLKL---HSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGL 1393 Query: 2331 G-----PDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSS 2385 P SPA E SS +P T G+ PS GR Sbjct: 1394 PRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKP 1453 Query: 2386 -TASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPV 2444 +ASD + +PQ R S+ PL P + K ++ Q P Sbjct: 1454 LSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTP---- 1509 Query: 2445 TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKS-- 2502 APA P + A P +AQ Q P + S Sbjct: 1510 --------------------------SPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTP 1543 Query: 2503 ---HRVSGKERP---NHSRGDPSHVTQPPPAQGSKEVLRAPGSPHS-----QQLHPPSPT 2551 + S +E P D S T+ A S L +P Q PPS + Sbjct: 1544 RLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVS 1603 Query: 2552 EHEVDVKTPASKPRPDQARED 2572 + + P PR A D Sbjct: 1604 QLPPEPPGPPGFPRVPSAGAD 1624 Score = 43.5 bits (101), Expect = 0.004 Identities = 91/344 (26%), Positives = 122/344 (35%), Gaps = 59/344 (17%) Query: 141 QLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPS 200 +L +L TP G P P T + P A FQ+P + Y++ S Sbjct: 3016 ELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTA--------FQQPRFQPPAPQYSAGS 3067 Query: 201 ATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPE-PIP 259 G P G Q +YP A ++P PGA++ PAEP P Sbjct: 3068 --------GGPTQNGFPAHQAPTYPGPSTYPAPAFP-------PGASY---PAEPGLPNQ 3109 Query: 260 KGSRPGG-------SPRGVSFQFPFPALHGAS-TKPFP---ADVAGHAFTNGPLVFAFHQ 308 + RP G P S FP PA A KP AD+ TN ++ + Sbjct: 3110 QAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVV 3169 Query: 309 PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPF 368 P + P E +GPA + QG+ + R D SP AP Sbjct: 3170 PMSSAPSETSYSGPAVSSGYE---------QGKVPEVPRAGDRGSVSQSP-----APTYP 3215 Query: 369 SDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLP--QRHFPGQAYRASGVDTSPGPPDTE 426 SDS + SL + +P D T+ S+ P QR P + PG P Sbjct: 3216 SDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGV- 3274 Query: 427 LAAPGPPPARLPQLWDPTAAPY-PTPPGGPLAATRSMFFNGQPS 469 L P P + Y P GG L RSM NG+P+ Sbjct: 3275 LDGPTLPCCYARGEEESEEDSYDPRGKGGHL---RSMESNGRPA 3315 Score = 42.7 bits (99), Expect = 0.007 Identities = 168/743 (22%), Positives = 230/743 (30%), Gaps = 186/743 (25%) Query: 2651 LSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKP-------------- 2696 +S+EGG DG PP A GPG G + AG G Q P Sbjct: 5 VSLEGGA-GDGPLPPGGAGPGPGPGPGPGAGKPPSAPAG--GGQLPAAGAARSTAVPPVP 61 Query: 2697 -----------PGD--RMLCPGRMDGAALGEQPTG-QKGASARGFWGPRETKALGVCKES 2742 PG R L P G PT Q A+ G PRET+A G + Sbjct: 62 GPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQE 121 Query: 2743 GSEP-----AEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSC----LQGL 2793 P + ++ RS + + P P P+ + P+ + C L Sbjct: 122 ADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTST 181 Query: 2794 PDNPDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKR 2853 P P+ Q ++V F P LT+ Sbjct: 182 PSQPNFNTCTQ--------------------CHNKVCNQCGFNPNPHLTQV--------- 212 Query: 2854 CEKPVLPLPTQPSFEEGGDPTLGPARLPTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLD 2913 K L L Q G D T P S +L H + P G P+ Sbjct: 213 --KEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPA---KQPLGKPDQE--- 264 Query: 2914 GFLNSRVPGIDPWAPGLSLWALEPSREAGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLE 2973 SR PG PG SR+A + S P + A PE+ G Sbjct: 265 ---RSRGPGGPQ--PG--------SRQAETARATS-VPGPAQAAAPPEV--------GRV 302 Query: 2974 MPAPADDSSSSLGDVSPEPPSLER---------------ERCDGGLPGNTHLLPLRATDF 3018 P P + S + P PP+ E E+ GL G L L A+ Sbjct: 303 SPQPPQPTKPSTAE--PRPPAGEAPAKSATAVPAGLGATEQTQEGLTGK--LFGLGASLL 358 Query: 3019 EVLSTKFEMQDLCFLGPFEDPVGLPGPSF----LDFEGTASSQGPQ------------SR 3062 ST +Q P D G P PS + F + GP+ Sbjct: 359 TQASTLMSVQ------PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGA 412 Query: 3063 RTEEAAGAGRAQGRGR-PAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPT----- 3116 +TE A G G G P G S K G + + A P T Sbjct: 413 KTEPGARMGPGSGPGALPKTGGTTSPKH----------GRAEHQAASKAAAKPKTMPKER 462 Query: 3117 --CYMC-VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNE--HLREHAV 3171 C +C E GS+ S A C C +V ++ +N HL E Sbjct: 463 AICPLCQAELNVGSK-------------SPANYNTCTTCRLQVCNLCGFNPTPHLVEKTE 509 Query: 3172 RFARRGQARR----SLGD---LPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAG-- 3222 Q +R SLG+ LP V + + +P +G + G+ +G Sbjct: 510 WLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVG-APHRASGTSPLKQKGPQGLGQPSGPL 568 Query: 3223 -SPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTP 3281 + P + +AKP S PS + A+ PP TTP Sbjct: 569 PAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTP 628 Query: 3282 SP-SPDPWAGGEPLLQATPVHEA 3303 +P +P +G ATPV +A Sbjct: 629 TPATPKVKSGVRRAEPATPVVKA 651 Score = 42.4 bits (98), Expect = 0.009 Identities = 71/273 (26%), Positives = 96/273 (35%), Gaps = 42/273 (15%) Query: 47 GAREAGGQAQAMELP----EAQPRQARDGELKPPSLRGQA-PSSTPGKRGSPQTPPGRSP 101 G EA +Q P + QP E PS A ++ K+GS Q G + Sbjct: 3675 GRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAA 3734 Query: 102 LQ------APSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQG 155 LQ A +L GR PQ+ SSR P+ PQ + Q QG Sbjct: 3735 LQSKAEPQAQPQLQGRQAAPGPQQS--QSPSSRQIPS-GAASRQPQTQQQQ-------QG 3784 Query: 156 PGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRG 215 G QP + L R Q+ S +T ++P+A+ P P S Sbjct: 3785 LGL-------------QPPQQALTQARLQQQ---SQPTTRGSAPAASQPAGKPQPGPSTA 3828 Query: 216 TSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQF 275 T P G Q +G+ A + P P + G+RPGG+P + Q Sbjct: 3829 TGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ- 3887 Query: 276 PFPALHGAS--TKPFPADVAGHAFTNGPLVFAF 306 P G S +K P A A V AF Sbjct: 3888 --PGADGESVFSKILPGGAAEQAGKLTEAVSAF 3918 Score = 42.0 bits (97), Expect = 0.012 Identities = 96/500 (19%), Positives = 145/500 (29%), Gaps = 78/500 (15%) Query: 2397 SHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSG 2456 S R+ + G+ L D +GY+++ + E Q G P +S Sbjct: 3440 SSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKP----------SSLSMA 3489 Query: 2457 PGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQP-------PRKKSHRVSGKE 2509 R R +P P PA PL P C P + H G Sbjct: 3490 HSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPR 3549 Query: 2510 RPNHSRG-----DPSHVTQPP----------------PAQGSKEVLRAPG----SPHSQQ 2544 + R D SH P + R G S SQ+ Sbjct: 3550 AHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQK 3609 Query: 2545 LHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSN 2604 P + H+ D + P P H E R G R S H+ + Sbjct: 3610 RGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRHGDHGRH-----SGRHTGEEPG 3663 Query: 2605 KKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYA--ASPSHCLSVEGGPEADGE 2662 ++ K R L P S + + P S A + PS S +D + Sbjct: 3664 RRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHA-SDSK 3722 Query: 2663 QPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGA 2722 + R A GP ++ AE + G A P + ++ A QP Q+ Sbjct: 3723 KGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQ 3782 Query: 2723 SARGFWGPRE--TKAL-------------------------GVCKESGSEPAEDSSRAHS 2755 G P++ T+A G +G +PA + Sbjct: 3783 QGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQT 3842 Query: 2756 RSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASG 2815 +G + P P PA + G P P Q G G + G Sbjct: 3843 NGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPG 3902 Query: 2816 SSAKDPPSLFDDEVSFSQLF 2835 +A+ L + +F + F Sbjct: 3903 GAAEQAGKLTEAVSAFGKKF 3922 Score = 41.6 bits (96), Expect = 0.016 Identities = 76/308 (24%), Positives = 105/308 (34%), Gaps = 79/308 (25%) Query: 407 PGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG 466 P A + G+ S GP A P PA LP+ Y T P P + RS Sbjct: 1363 PSSASKEIGMPFSQGPGTPATTAVAPCPAGLPR-------GYMT-PASPAGSERS----- 1409 Query: 467 QPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAG-GPEWQGGSQGALGTAG 525 PSP TA H P A G + + Q G A Sbjct: 1410 -PSPSS-----------------TAHSYGHS-------PTTANYGSQTEDLPQAPSGLAA 1444 Query: 526 KTPGPREKLPAVRSSQGGSP---ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPR 582 REK + +GG+P ++Y + P P + P SP +P PR Sbjct: 1445 AGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSP-----SSPSESPTFSPGKMGPR 1499 Query: 583 VVGASPSESPLPSPATNTAGST-CSSLSPM----SSSPANPSS-----EESQLPGP---- 628 +++P P+PA++ S + SPM + +P PS+ +ES P Sbjct: 1500 ATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559 Query: 629 ------------LGPSAFFHP---PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFP- 672 + SA P PT Q T + PP + PEP FP Sbjct: 1560 TLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS--VSQLPPEPPGPPGFPR 1617 Query: 673 ADGLGAEG 680 GA+G Sbjct: 1618 VPSAGADG 1625 Score = 40.8 bits (94), Expect = 0.027 Identities = 53/187 (28%), Positives = 72/187 (38%), Gaps = 35/187 (18%) Query: 3683 LARGTENGMKP---ATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAK 3739 L G +G P A P PGP G G+ +P + GG Q PA+G +S TA P Sbjct: 7 LEGGAGDGPLPPGGAGPGPGPGP---GPGAGKPPSAPAGGGQ-LPAAGAARS-TAVPPVP 61 Query: 3740 PSFPSRSPAP------ERL-------------PARAQAKSCTKG---PREAGEQGPHGSL 3777 P P P RL P QA + T G PRE QGP Sbjct: 62 GPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGP---A 118 Query: 3778 GPKEKGESSTKRKKGQVPGPARSESVG-SFGRAPSAPDKPPR-TPRKQATPSRVLPTKPK 3835 G + G T + + RS SV G P++P P+ P +T + T Sbjct: 119 GQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDL 178 Query: 3836 PNSQNKP 3842 ++ ++P Sbjct: 179 TSTPSQP 185 Score = 40.8 bits (94), Expect = 0.027 Identities = 70/281 (24%), Positives = 98/281 (34%), Gaps = 30/281 (10%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELP 61 P PRG P + SS H ++T + G A A Sbjct: 1390 PAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAA 1449 Query: 62 EAQPRQARDGE---LKPPSLRGQAPSSTPGKRGSPQTP--PGRSPLQAPSRLAGRAEGSP 116 +P A DGE +P SS+P P +P P SP +P ++ RA Sbjct: 1450 REKPLSASDGEGGTPQPSRAYSYFASSSP-----PLSPSSPSESPTFSPGKMGPRATAE- 1503 Query: 117 PQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176 S P+ + P+ A P QG T P RP PR Q +++ Sbjct: 1504 ---------FSTQTPSPAPASDMPRSPGAPTPSPMVAQG--TQTPHRPSTPRLVWQESSQ 1552 Query: 177 ELGFH-RCFQEPPSSFTSTNYTSPSATPR-PPAPGPPQSRGTSPLQPGSYPEY--QASGA 232 E F SS T + S S +P P P + G S P S + + G Sbjct: 1553 EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGP 1612 Query: 233 DSWP--PAAENSFPGA--NFGVPPAEPEPIPKGSRPGGSPR 269 +P P+A P A +G PAE + + S G+ R Sbjct: 1613 PGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSR 1653 Score = 40.8 bits (94), Expect = 0.027 Identities = 42/146 (28%), Positives = 62/146 (42%), Gaps = 23/146 (15%) Query: 3671 PRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQ 3730 P++A+ + ++ T G PA +SQ +G P+PG T G PQPA Sbjct: 3790 PQQALTQARLQQQSQPTTRGSAPA--------ASQPAGKPQPGPSTATG--PQPAGPPRA 3839 Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKSCTK-GPREAGEQG-PHGSLGPKEKGESSTK 3788 +T + P + AP+ PA + K G R G G P G P GES Sbjct: 3840 EQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ--PGADGESVFS 3897 Query: 3789 RKKGQVPGPAR------SESVGSFGR 3808 + +PG A +E+V +FG+ Sbjct: 3898 K---ILPGGAAEQAGKLTEAVSAFGK 3920 Score = 40.0 bits (92), Expect = 0.046 Identities = 108/444 (24%), Positives = 139/444 (31%), Gaps = 105/444 (23%) Query: 211 PQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPG-------ANFGVPPAEPEPIPKGSR 263 P + PL PG+ P A+ P + +S G +P+ S Sbjct: 1300 PMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSS 1359 Query: 264 PGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPA 323 P SP S + P G T PA A G P+G PA Sbjct: 1360 P-ASPSSASKEIGMPFSQGPGT---PATTAVAPCPAG-------LPRGYMT-------PA 1401 Query: 324 YPLPTQPAPSP---LPCYQGQPGGLNRHS---DLSGALSSPGAAHSAPRPFSDSLHKSLT 377 P ++ +PSP Y P N S DL A S AA A R Sbjct: 1402 SPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAR----------- 1450 Query: 378 KILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARL 437 E+P SA DG G T PQ P +AY + P P + +P P ++ Sbjct: 1451 ----EKPLSASDGEGGT-------PQ---PSRAYSYFASSSPPLSPSSPSESPTFSPGKM 1496 Query: 438 PQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQS--APLPWPQVLPTARPSP 495 GP A F PSP +P+S AP P P V + +P Sbjct: 1497 ----------------GPRATAE--FSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQ-TP 1537 Query: 496 H--------GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547 H E PF SQ + A + P + S P Sbjct: 1538 HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSP------LCSPTETQPTT 1591 Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSS 607 Y+ T P V+Q P G P P GA + PL + S Sbjct: 1592 HGYSQTTPP-------SVSQLPPEPPGPPGFPRVPSAGA---DGPLALYGWGALPAENIS 1641 Query: 608 LSPMSSSPANPSSEESQLPGPLGP 631 L +SS P E PGP P Sbjct: 1642 LCRISSVPGTSRVE----PGPRTP 1661 Score = 40.0 bits (92), Expect = 0.046 Identities = 51/242 (21%), Positives = 77/242 (31%), Gaps = 13/242 (5%) Query: 3593 SGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQS-- 3650 S K G GR + H E+ + + H G H ++ PA + Sbjct: 3641 SAKEHRHGDHGRHSGRHTGEE----PGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQ 3696 Query: 3651 ----SSKDRSAASTPSKALKFPVHPRKAVGSL--APGELARGTENGMKPATPKAKPGPSS 3704 SS + S S S A +K P L E +P + P Sbjct: 3697 PGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGP 3756 Query: 3705 QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG 3764 Q S SP G + QP + Q Q P + + + P + Sbjct: 3757 QQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQ 3816 Query: 3765 PREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824 P + GP + GP+ G ++ G G A++ G +A AP P + A Sbjct: 3817 PAGKPQPGPSTATGPQPAGPPRAEQTNGS-KGTAKAPQQGRAPQAQPAPGPGPAGVKAGA 3875 Query: 3825 TP 3826 P Sbjct: 3876 RP 3877 Score = 39.3 bits (90), Expect = 0.078 Identities = 106/447 (23%), Positives = 145/447 (32%), Gaps = 97/447 (21%) Query: 5 RPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAG----------GQ 54 RP G P P GD P Q SS P + P K RE G Sbjct: 3515 RPAGGPLPP-GGDTCP-QFCSSHSMPDVQEHVKDGPRAHAYK--REEGYILDDSHCVVSD 3570 Query: 55 AQAMELPEAQ------PRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRL 108 ++A L + + PR AR + G A SS+ KRG P+R Sbjct: 3571 SEAYHLGQEETDWFDKPRDARSDRFRHHG--GHAVSSSSQKRG-------------PARH 3615 Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168 + PP+ + DE A + D + G PG R Sbjct: 3616 SYHDYDEPPEEGLW---------PHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPG--R 3664 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228 A+P A +LG H + ++ PS+ P P G P P S Q Sbjct: 3665 RAAKPHARDLGRHE----------ARPHSQPSSAPAMPKKGQPG-------YPSSAEYSQ 3707 Query: 229 ASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF 288 S A S A +S G+ + P + + P P+ L G P Sbjct: 3708 PSRASSAYHHASDSKKGSRQA--HSGPAALQSKAEPQAQPQ----------LQGRQAAPG 3755 Query: 289 PADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348 P + P A QPQ ++ +G P TQ L + Sbjct: 3756 PQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQ-------------ARLQQQ 3802 Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPG 408 S + S+P A+ A +P + T P PP A+ GS + PQ+ Sbjct: 3803 SQPTTRGSAPAASQPAGKPQPGP--STATGPQPAGPPRAEQTNGSK--GTAKAPQQGRAP 3858 Query: 409 QAYRASGVDTSPGPPDTELAA-PGPPP 434 QA A G PGP + A PG P Sbjct: 3859 QAQPAPG----PGPAGVKAGARPGGTP 3881 Score = 38.9 bits (89), Expect = 0.10 Identities = 58/234 (24%), Positives = 80/234 (34%), Gaps = 30/234 (12%) Query: 422 PPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLA---ATRSMFFNGQPSPGQRLCLPQ 478 P +AP P P P++A Y P A A+ S + Q G + Sbjct: 3681 PHSQPSSAPAMPKKGQPGY--PSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSK 3738 Query: 479 SAPLPWPQVLPT-ARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAV 537 + P PQ+ A P P + S P+G Q +Q G P P++ L Sbjct: 3739 AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQP-PQQALTQA 3797 Query: 538 RSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA 597 R Q +QP G A P G P P G P+ P A Sbjct: 3798 RLQQQ---------------SQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG---PPRA 3839 Query: 598 TNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSP 651 T GS ++ +P P ++ + PGP G A P P G+P P Sbjct: 3840 EQTNGSKGTAKAPQQGRA--PQAQPAPGPGPAGVKAGARPGGTP---GAPAGQP 3888 Score = 38.1 bits (87), Expect = 0.17 Identities = 133/590 (22%), Positives = 196/590 (33%), Gaps = 155/590 (26%) Query: 628 PLGPSAF----FHPPTHPQETGSPFPSPE--PPHSLPTHYQPE--PAKAFP----FPAD- 674 P GP+AF F PP GS P+ P H PT+ P PA AFP +PA+ Sbjct: 3045 PSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEP 3104 Query: 675 GLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCR 734 GL + AF+ P H + P PT +L D L R Sbjct: 3105 GLPNQQAFR-----PTGHYAGQT-------------PMPTTQSTLFPVPADSRAPLQKPR 3146 Query: 735 QCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHA 794 Q +SLA D Q+ P + + P P A + S++ Sbjct: 3147 Q-----TSLA-----------------DLEQKVPTNYEVIASPVVPMSSAPSET---SYS 3181 Query: 795 KTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASD---LDMEDDAKLDSLITEALNGM 851 + +G Q + + P R G S++ +P P SD +E + + ++ + ++ + Sbjct: 3182 GPAVSSGYEQGKVPEVP-RAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISEL 3240 Query: 852 EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911 S + DS + EP GP SSG P K P P P P Sbjct: 3241 TKDSTSTAPDSQRL------EPLGP--GSSGRPGKE-----------PGEPGVLDGPTLP 3281 Query: 912 RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971 C ARG ++ P RGK GG S G Sbjct: 3282 -----CCYARGEEESEEDSYDP-------------RGK-----------GGHLRSMESNG 3312 Query: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLP 1031 RP G+ R PG P A A RS R++ Sbjct: 3313 -------RPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQ-- 3363 Query: 1032 PRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEED--EQPPPRGPGFRGRRGR 1089 G E Q+ ++ + A + E D PPP RGR Sbjct: 3364 ---------------GME------QKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGR 3402 Query: 1090 GEKRKEVELTQGPRED--EPQKPRKAARQEA-------GGDGAPANPEEPGGSR-PGPGR 1139 + + E+T G +++ E QK + ++A GG P G + Sbjct: 3403 ---KFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDF 3459 Query: 1140 SPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRP 1189 S +G R E ++ GPK + + ++ P ++ SEE P Sbjct: 3460 SGWGKGYEREREAVERLQKAGPKPSSLSMAHSR--VRPPMRSQASEEESP 3507 Score = 38.1 bits (87), Expect = 0.17 Identities = 60/219 (27%), Positives = 76/219 (34%), Gaps = 36/219 (16%) Query: 328 TQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDS------LHKSLTKILP 381 +QP+ +P +GQPG + S S P A SA SDS H + Sbjct: 3683 SQPSSAPAMPKKGQPGYPS-----SAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737 Query: 382 ERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPG----PPP--- 434 + P AQ L + P Q P SG + P T+ G PP Sbjct: 3738 KAEPQAQPQLQGRQAAPGP-QQSQSPSSRQIPSGAASRQ--PQTQQQQQGLGLQPPQQAL 3794 Query: 435 --ARLPQLWDPT--------AAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPW 484 ARL Q PT + P P GP AT G P Q +A P Sbjct: 3795 TQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPA-GPPRAEQTNGSKGTAKAPQ 3853 Query: 485 ----PQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQG 519 PQ P P P G++ +R G P Q G+ G Sbjct: 3854 QGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADG 3892 Score = 37.7 bits (86), Expect = 0.23 Identities = 41/161 (25%), Positives = 58/161 (36%), Gaps = 24/161 (14%) Query: 566 AQPQVSPH--GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623 A+PQ P G + P P+ SPS +PS A + T + P + ++ Sbjct: 3739 AEPQAQPQLQGRQAAPGPQQ-SQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQA 3797 Query: 624 QLPGPLGPSAFFHPPTHPQETGSPFPSPE---------PPHSLPTHYQPEPAKAFPFPAD 674 +L P+ P Q G P P P PP + T+ AKA P Sbjct: 3798 RLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA---PQQ 3854 Query: 675 GLGAEGAFQCLEETPFPHEGPEVGRGGLQ--GFPRAPPPYP 713 G + + P P GP + G + G P AP P Sbjct: 3855 G-------RAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888 Score = 37.7 bits (86), Expect = 0.23 Identities = 38/165 (23%), Positives = 54/165 (32%), Gaps = 18/165 (10%) Query: 12 PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDG 71 P LQ RQ A P P + + + Q ++ P+ QAR Sbjct: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQ 3800 Query: 72 ELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKP 131 + P+ RG AP++ + P P PS G PP+ + +T Sbjct: 3801 QQSQPTTRGSAPAA---------SQPAGKPQPGPSTATGPQPAGPPR-------AEQTNG 3844 Query: 132 TLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176 + Q A Q P G A RPG T PA + Sbjct: 3845 SKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPG--GTPGAPAGQ 3887 Score = 37.4 bits (85), Expect = 0.30 Identities = 31/103 (30%), Positives = 42/103 (40%), Gaps = 13/103 (12%) Query: 79 RGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSP-PQRYILGIASSRTKPTLDETP 137 R APS P + PP P+ A +A G+ P R + + ++R +P TP Sbjct: 2260 RYPAPSRFPI---ASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTP 2316 Query: 138 EN---------PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEA 171 P A Q P D G G+GA RPG + EA Sbjct: 2317 AAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEA 2359 Score = 37.0 bits (84), Expect = 0.39 Identities = 53/229 (23%), Positives = 77/229 (33%), Gaps = 40/229 (17%) Query: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL 2040 P G ASP + P+ + S + + E P PS + Sbjct: 1390 PAGLPRGYMTPASPAGSERSPSPSSTA-HSYGHSPTTANYGSQTEDLPQAPSGLAAAGRA 1448 Query: 2041 ALTAAHSRSGSEGRTPE--------RASSPGLN------KPLLATGDSPAPSVGDLAACA 2086 A S S EG TP+ +SSP L+ P + G + + + Sbjct: 1449 AREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQT 1508 Query: 2087 PSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPS-----------------CR 2129 PSP A+ MP S G P SP AQG P++P Sbjct: 1509 PSPAPASDMPRSPGA-----PTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLAS 1563 Query: 2130 DPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP 2178 D +++ S + +PL Q TT S PPS++ P +P Sbjct: 1564 DASSQTRMVHASASTSPLCSPTETQPTTH---GYSQTTPPSVSQLPPEP 1609 Score = 37.0 bits (84), Expect = 0.39 Identities = 65/258 (25%), Positives = 83/258 (32%), Gaps = 51/258 (19%) Query: 1751 EPGT-ADQPH-RGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATW--PFGASPS-HAAQG 1805 EPG A +PH R EA AP + +G P A + P AS + H A Sbjct: 3661 EPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASD 3720 Query: 1806 HSAGRAGGHLHPTA--------GRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVS 1857 G H P A +P +G + AP G +P R+ +PS A Sbjct: 3721 SKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAP-GPQQSQSPSSRQ-----IPSGAASR 3774 Query: 1858 NTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTV 1917 ++ Q L PP + L + QS P T Sbjct: 3775 QPQTQQQQQGLGLQPPQQ-----------------ALTQARLQQQSQP----------TT 3807 Query: 1918 EGGKVACGPAQGSPG-GVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPE 1976 G A G P G T P AG + +G G K QG A Q QP Sbjct: 3808 RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKG----TAKAPQQGRAPQAQPA 3863 Query: 1977 NGVSPGGTDNHASVNASP 1994 G P G A +P Sbjct: 3864 PGPGPAGVKAGARPGGTP 3881 Score = 36.2 bits (82), Expect = 0.66 Identities = 54/200 (27%), Positives = 75/200 (37%), Gaps = 30/200 (15%) Query: 869 ADEEPSGPRGPSSGHP-LKSKAGVTPESKAPPPLPA--ATPDPQTPR-PGDRGCP---AR 921 A + G R SG L+SKA E +A P L A P PQ + P R P A Sbjct: 3718 ASDSKKGSRQAHSGPAALQSKA----EPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS 3773 Query: 922 GRPKTRS----LGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASG 977 +P+T+ LGL P P Q Q R +Q S GS A Sbjct: 3774 RQPQTQQQQQGLGLQP-----PQQALTQARLQQ--------QSQPTTRGSAPAASQPAGK 3820 Query: 978 LRPRRNDGLGERP--PPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKD 1035 +P + G +P PPR + ++A R P+A P + + P Sbjct: 3821 PQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT 3880 Query: 1036 PRKRKARGGAWGKELILKIV 1055 P + GA G+ + KI+ Sbjct: 3881 PGAPAGQPGADGESVFSKIL 3900 Score = 34.3 bits (77), Expect = 2.5 Identities = 42/176 (23%), Positives = 58/176 (32%), Gaps = 27/176 (15%) Query: 321 GPAYPLPTQPAPSPLPC---YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLT 377 G A + +P P P P ++ P L H AL H+ + ++T Sbjct: 1822 GTAQSIGLKPGPVPEPGAEPHRATPAELRSH-----ALPGARKPHTVVVQMGEGTAGTVT 1876 Query: 378 KILPERPPSAQDGLGSTRGPPSSLP----QRHFPGQAYRASGVDTSPGPPDTELAAPGPP 433 +LPE P A D G P S L P + +P P+ +A PP Sbjct: 1877 TLLPEEPAGALDLTGMR--PESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPP 1934 Query: 434 PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489 + P P PP + G PG P P+PQ LP Sbjct: 1935 GQSSSPFYGPRDPEPPEPP--------TYRAQGVVGPG-----PHEEQRPYPQGLP 1977 Score = 33.9 bits (76), Expect = 3.3 Identities = 120/515 (23%), Positives = 174/515 (33%), Gaps = 137/515 (26%) Query: 3452 PGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCS-------EVAPSTTKGWPETL--ERP 3502 PG P PG P P G+LP S A S P+T+ ER Sbjct: 404 PGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERA 463 Query: 3503 VDPVTHPIR--GCELPSNHQECPPPSL--------SPFPAALADGRG---DCALDGALER 3549 + P+ G + P+N+ C L +P P + +C LE Sbjct: 464 ICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEG 523 Query: 3550 PENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGR-CAPD 3608 E +P P P QQ P+GA G +PL K++ P G+ P Sbjct: 524 SLGEPTP-LPPPTSQQP-PVGAPHRASGT---------SPL----KQKGPQGLGQPSGPL 568 Query: 3609 HFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP 3668 + L K +S + S+ P+ + A++P+ SS +++ P+KA P Sbjct: 569 PAKASPLSTK-----ASPLPSKASPQAKPLR--ASEPSKTPSSVQEKK-TRVPTKAEPMP 620 Query: 3669 VHPRKAVGSLAPGELARGTENGMKPATPKAKPGP----------------SSQGSGSPRP 3712 P + + A ++ G +PATP K P S S SP+ Sbjct: 621 KPPPETTPTPATPKVKSGVRRA-EPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQS 679 Query: 3713 GTKTGGGSQ------------PQPASGQLQSETATTPAKPSFPSR------SPAP----E 3750 + TG S Q QL S T P PS PS S P + Sbjct: 680 LSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPS-PSEIHKVGSSMRPLLQAQ 738 Query: 3751 RLPARAQAKSCTKGPREAGEQGPHG-SLGPK------------EKGESST--KRKKGQVP 3795 L ++K + G E +Q PH S+ P+ E+ E S +R++ Q Sbjct: 739 GLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQD 798 Query: 3796 GPARSESVGS------------FGRAPSAPDKPPRTP--------RKQ------------ 3823 S+ GS G +P P P R R+Q Sbjct: 799 TAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLE 858 Query: 3824 ----ATPSRVLPTKPKPNSQNKPRPPPSEQRKAEP 3854 AT R L +PRP PS++ A P Sbjct: 859 EDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALP 893 Score = 33.1 bits (74), Expect = 5.6 Identities = 56/233 (24%), Positives = 79/233 (33%), Gaps = 47/233 (20%) Query: 1104 EDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKC 1163 ED PQ P A A G A E+P + G G +PQ PSR+ A++ Sbjct: 1433 EDLPQAPSGLA---AAGRAA---REKPLSASDGEGGTPQ---PSRAYSYFASS------- 1476 Query: 1164 ADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAA 1223 P ++P P + PT + R + +F + ++P A Sbjct: 1477 --SPPLSPSSPSESPTFSPGKMGPRATAEF----------------------STQTPSPA 1512 Query: 1224 CAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283 A +M SPG P P T TP + S P + L +Q Sbjct: 1513 PASDMPRSPG--APTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTR 1570 Query: 1284 VSH-NSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDP 1335 + H ++ P P E S T P S L + P GF R P Sbjct: 1571 MVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPG----PPGFPRVP 1619 Score = 33.1 bits (74), Expect = 5.6 Identities = 52/219 (23%), Positives = 81/219 (36%), Gaps = 22/219 (10%) Query: 967 SGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSR 1026 +G G RA+ +P D LG R RP + AP P P +A + +R+S Sbjct: 3658 TGEEPGRRAA--KPHARD-LG-RHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASS 3713 Query: 1027 RRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP----PRGPG 1082 R+A G + + Q + +L+ A ++ + P P G Sbjct: 3714 AYHHASDSKKGSRQAHSGPAALQSKAE-PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAA 3772 Query: 1083 FRG------RRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSR-- 1134 R ++G G + + LTQ + + Q R A PA +PG S Sbjct: 3773 SRQPQTQQQQQGLGLQPPQQALTQARLQQQSQP---TTRGSAPAASQPAGKPQPGPSTAT 3829 Query: 1135 -PGPGRSPQARGPSRSLETGAAAREG-GPKCADRPSVAP 1171 P P P+A + S T A ++G P+ P P Sbjct: 3830 GPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGP 3868 Score = 32.7 bits (73), Expect = 7.3 Identities = 26/110 (23%), Positives = 38/110 (34%), Gaps = 1/110 (0%) Query: 4 ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEA 63 + P P+ QP+ G QPP + T A + G A A P Sbjct: 3760 QSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAG 3819 Query: 64 QPRQARDGELKPPSLRGQAPSSTPGKRGSPQTP-PGRSPLQAPSRLAGRA 112 +P+ P T G +G+ + P GR+P P+ G A Sbjct: 3820 KPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPA 3869 Score = 32.3 bits (72), Expect = 9.5 Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 12/88 (13%) Query: 3215 RSAGKAAGSP-GDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGS 3273 R + AA P G P Q G + P PRA T + A P A A Sbjct: 3808 RGSAPAASQPAGKP--QPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPG 3865 Query: 3274 PGP--------PRTTP-SPSPDPWAGGE 3292 PGP P TP +P+ P A GE Sbjct: 3866 PGPAGVKAGARPGGTPGAPAGQPGADGE 3893 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 98.6 bits (244), Expect = 1e-19 Identities = 179/738 (24%), Positives = 246/738 (33%), Gaps = 131/738 (17%) Query: 10 PPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAME---------L 60 P G L PR PG P PP TPA GA A G+ E + Sbjct: 17 PAARAPGLLTPRP----PGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120 PE+ PR P+ + P+S G+R P P+ +P R +G P + Sbjct: 71 PESAPRAG-------PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 Query: 121 ILGIASSRT--KPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEEL 178 L I++ T + E P+ L A + P PGT +P ++ A E+ Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAM----ARRSRAAGTEV 178 Query: 179 GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPA 238 G R +PSA PRPP GP +S ++ + + S A P+ Sbjct: 179 GLPR--------------PAPSARPRPPTEGPRKSVSSA----SEHSTTEPSPAARRRPS 220 Query: 239 AENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP------FPADV 292 A + P+ +R G S RG P H + KP P V Sbjct: 221 AGGGLQRPASRSLSSSATPLSSPARSGPSARGT----PRAPAHPSQPKPKGLQALRPPQV 276 Query: 293 AGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-----LPTQPA--PSPLPCYQGQPGGL 345 P + A P + P+ P LP+ PA PS G P Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336 Query: 346 NRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS-AQDGLGSTRGPPSSLPQR 404 HS L SP + A P P+ PP+ A L + PP+S P Sbjct: 337 ATHS----FLPSPPLSPLATPP-------------PQAPPALALPPLQAPPSPPASPPLS 379 Query: 405 HF---PGQAYRASGVDT-----SPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPL 456 QA A V SP PP + AP PPA P +P TPP Sbjct: 380 PLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPFSPPA------SPPVSPSATPPSQAP 432 Query: 457 AATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGG 516 + + PSP P S P+ P+A P P L+ P P Q Sbjct: 433 PSLAAPPLQVPPSP------PASPPMS-----PSATPPPQAPPPLAAPPLQLAKPPPQAP 481 Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG-VAQPQVSPHGT 575 A P P P + + P A P+ + Q SP + Sbjct: 482 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 541 Query: 576 PSLPPPR----------------VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPS 619 P+L PR + +P P PS + ++ S SS+ + P Sbjct: 542 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 601 Query: 620 SEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPF-PADGLGA 678 GP G +A PP P P + P ++ P P+ PA G G+ Sbjct: 602 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP-APPLAFRGAPGAPLPWPPATGPGS 660 Query: 679 EGAFQCLEETPFPHEGPE 696 + ET EGPE Sbjct: 661 ADGLCTIYET----EGPE 674 Score = 97.1 bits (240), Expect = 3e-19 Identities = 155/607 (25%), Positives = 205/607 (33%), Gaps = 123/607 (20%) Query: 8 GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATR-TTKGAREAGGQAQAMELPEAQPR 66 G P P M + R + G P P P T K A + P A+ R Sbjct: 161 GTPSPAMAR--RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218 Query: 67 QARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIAS 126 + G L+ P+ R + S+TP + P R +AP+ P Q G+ + Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH--------PSQPKPKGLQA 270 Query: 127 SR----TKPTLDETPENPQLEAAQL--PEVDTPQGPGTGAPLR--PGLPRTEAQPAAEEL 178 R T P D P L ++ L P P P L+ P P T A L Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330 Query: 179 G------FHRCFQEPP-SSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASG 231 G H PP S + +P A PP PP + PL P + P QA Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390 Query: 232 A---------DSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVS---FQFP--F 277 A S PP+ P + PPA P P + P +P ++ Q P Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFS----PPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446 Query: 278 PALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPC 337 PA S P A PL A PQ A+ T P LP+ PA P Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA---PPALATPPLQALPSPPASFP--- 500 Query: 338 YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGP 397 GQ + S + S P + + P P + + + +P PP A L + R P Sbjct: 501 --GQ-------APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP-ASPTLQAPRRP 550 Query: 398 PSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQ--LWDPTAAPYPT----- 450 P+ P G + +PGPP PPP+R P L P A + + Sbjct: 551 PTPGPDTSVSGPRLTLA---LAPGPP--------PPPSRSPSSTLSGPDLAGHSSSATST 599 Query: 451 -------------------PPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTA 491 PP LAA ++ P+P APLPWP Sbjct: 600 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP------ 653 Query: 492 RPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYN 551 PA GP GS L T +T GP PA + G P+ T Sbjct: 654 ---------------PATGP----GSADGLCTIYETEGPESATPAPGALDPG-PSPGTSG 693 Query: 552 GMTDPGA 558 G GA Sbjct: 694 GKAAAGA 700 Score = 91.7 bits (226), Expect = 1e-17 Identities = 152/575 (26%), Positives = 198/575 (34%), Gaps = 119/575 (20%) Query: 202 TPRPP-APGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIP- 259 TPRPP +P PP P+ P + A+GA P AE + +P + P P Sbjct: 26 TPRPPGSPRPPP-----PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80 Query: 260 KGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTN---GPLVFAFHQPQGAWPEE 316 + SRP S RG A +T P P G A GPL + EE Sbjct: 81 RTSRPPASGRGER------APPAKNTSPGPVSSPGRASGTTRPGPLG---QKGLRISAEE 131 Query: 317 AVGTGPAYPLPTQPAPS---------PLPCYQGQPG-GLNRHSDLSGA-LSSPGAAHSA- 364 V G A P + A S P P G P + R S +G + P A SA Sbjct: 132 TVARGKATEAPKRSALSAGARRDTSGPTP---GTPSPAMARRSRAAGTEVGLPRPAPSAR 188 Query: 365 PRPFSDSLHKSLTKI----------LPERPPSAQDGLG-------STRGPPSSLPQRHFP 407 PRP ++ KS++ R PSA GL S+ P S P R P Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248 Query: 408 GQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY---PTPPGGPLAATRSMFF 464 A G +P P P P L L P P P GPL+ Sbjct: 249 S----ARGTPRAPAHPSQ------PKPKGLQALRPPQVTPPRKDAAPALGPLS------- 291 Query: 465 NGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG----GSQGA 520 S+PL P P+A PSP L LP P P Q GS Sbjct: 292 --------------SSPLATPS--PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335 Query: 521 LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP 580 T P P L + + +P + P + P A P +SP TPS Sbjct: 336 QATHSFLPSP--PLSPLATPPPQAPPALALPPLQAPPSPP-----ASPPLSPLATPSPQA 388 Query: 581 PRVVG--------ASPSESPLPSPATNTAGSTCS-SLSPMSSSPANPSSEESQLPG---- 627 P + + P P+ +P + A S S +P S +P + ++ Q+P Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448 Query: 628 --PLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCL 685 P+ PSA P P P +PP P P +A P P + F Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508 Query: 686 EETPF------PHEGPEVGRGGLQGFPRAPPPYPT 714 P P + P V L P +PP PT Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543 Score = 75.5 bits (184), Expect = 1e-12 Identities = 161/648 (24%), Positives = 212/648 (32%), Gaps = 112/648 (17%) Query: 875 GPRGPSSGHPLKSKAG-----VTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSL 929 G G PL +AG PES AP P T P G+R PA K S Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPES-APRAGPTRTSRPPASGRGERAPPA----KNTSP 102 Query: 930 GLAPTEADAPSQGRQQRRG-KQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGE 988 G + A R G K L++ ++ + G A + A R G Sbjct: 103 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162 Query: 989 RPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGK 1048 P RR R A G+ LP S+R R PP + PRK + Sbjct: 163 PSPAMARRSR--AAGTE----------VGLPRPAPSARPR--PPTEGPRKSVSSAS---- 204 Query: 1049 ELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQ 1108 E+ S + P G G + R L+ Sbjct: 205 --------------EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS--------- 241 Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPS 1168 P ++ G APA+P +P R PQ P + P PS Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301 Query: 1169 VAPK-------DPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPP 1221 P L P T S+ T SL P + + S P S T ++PP Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQAT-TSLGSP-TLQATHSFLPSPPLSPLATPPPQAPP 359 Query: 1222 AACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLA---NTAPHGSSPTPGVGSLLGGPG 1278 A + A P P PP S T +P+ +LA AP P+P V Sbjct: 360 ALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-------- 409 Query: 1279 GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGV 1338 QAP S PPA P ++P A P S A PS+ + + PA P Sbjct: 410 --QAPFS-----PPASPP---VSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSAT 457 Query: 1339 PVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLE 1398 P + P P ++P +L P P A +PPAS G+ S Sbjct: 458 P-PPQAPPPLAAPPLQLAKPPPQAPPALAT---PPLQALPSPPASF-----PGQAPFSPS 508 Query: 1399 PQLPRSPPGTAETEPGRAASPPTLE---SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFA 1455 LP SP T + + P L+ S P L R PP G ++ L A Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR-RPPTPGPDTSVSGPRLTLA 567 Query: 1456 CADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPE 1503 A P PP PS SP PDL+G + + P E Sbjct: 568 LA-------PGPPPPPS------RSPSSTLSGPDLAGHSSSATSTPEE 602 Score = 73.9 bits (180), Expect = 3e-12 Identities = 165/692 (23%), Positives = 225/692 (32%), Gaps = 98/692 (14%) Query: 1761 GAPAPEAF--GSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHP- 1817 GA PE+ P P + +G+ APP T P S S GRA G P Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVS--------SPGRASGTTRPG 118 Query: 1818 TAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIR-- 1875 G+ G + T R A + + A + P+ + PA++ R Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSA----LSAGARRDTSGPTPGTPSPAMARRSRAA 174 Query: 1876 --QLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACG-PAQGSPG 1932 ++ LP P + P + P + S E T E A P+ G G Sbjct: 175 GTEVGLPRPAPSARP---------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG--G 223 Query: 1933 GVQVTTLPAVAGHQLGLEADGHWGLLGQ------AEKTQGQGTANQLQPENGVSPGGTDN 1986 G+Q +++ L + G + A +Q + Q V+P D Sbjct: 224 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 283 Query: 1987 HASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL-ALTAA 2045 ++ + L P+ A A SLQ P +PPS SL L A Sbjct: 284 APALGPLSSSPLATPSPSAP-----PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338 Query: 2046 HSRSGSEG----RTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGP 2101 HS S TP + P L P L SP S PSP + + L Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398 Query: 2102 LPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGA 2161 P P + P +A P SPS P LA P P + A Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSA 456 Query: 2162 EDSPVAPPSLTTSPC-------DPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSG 2214 P APP L P ALA LQ SP P+S+P G Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP---PASFP------------G 501 Query: 2215 DTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP--SVAVRATGLSSTPTGDEAQAG 2272 P + +P ++P +P L SP S ++A TP D + +G Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561 Query: 2273 RGL-----PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARL-GHREGQAVTAVPTEPPT 2326 L PGP P +P T GHSS + S L G+ G A + PP Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621 Query: 2327 LQGA---------GPDSPACLEGEMGTSSKEP--EDPGTPE--------TGRSGATKMPR 2367 + A GP P G G P PG+ + G AT P Sbjct: 622 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681 Query: 2368 VTCPSTGLGLGRTTAPSSTASDFQSDSPQSHR 2399 P G A + + S SP+ R Sbjct: 682 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 713 Score = 71.6 bits (174), Expect = 1e-11 Identities = 198/785 (25%), Positives = 264/785 (33%), Gaps = 130/785 (16%) Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPS 1168 K AAR A P PG RP P +P A R L GAA G A+R Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAA---LRVL--GAAGAVGRKPLAERAG 63 Query: 1169 VAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAE-ESAPDSTEFTEALRSPPAACAGE 1227 T E+ P + ++ P + E AP + + S P +G Sbjct: 64 ---------GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGT 114 Query: 1228 MGASP----GLLIPEQPPPSR-HDTGTPKPSGSLANTAPHGSSPTPGVGS--------LL 1274 P GL I + +R T PK S A S PTPG S Sbjct: 115 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 174 Query: 1275 GGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCD-PAGFNR 1333 G G P PP P + ++ A+ ST P P+ + G PA + Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSS-ASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233 Query: 1334 DPLGVPV---AKKGPQPYSSPHSELFLGPKDLAGCFLEELHP---KPSARDAPPA----S 1383 P+ A+ GP +P + G L+ L P P +DA PA S Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQALRPPQVTPPRKDAAPALGPLS 291 Query: 1384 SSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSL-FPDLPVDRF---DPP 1439 SS L A P P +PP + +T P A+PP+ ++SL P L PP Sbjct: 292 SSPLATPSPSA----PPSPSAPP-SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346 Query: 1440 LYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFP-DLSGGKVLSK 1498 L S A P A A PP + PS P P L SP P+ L Sbjct: 347 L--SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404 Query: 1499 TCPP-ERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAP 1557 PP + P A+P + + S A S L+ L++ + AP Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPASPPMSPSATPPPQAP 463 Query: 1558 RELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVA 1617 LA ++L +PP Q AT P Sbjct: 464 PPLAAPP----LQL---AKPPPQAPPALATPP---------------------------- 488 Query: 1618 TVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKT 1677 +Q P PASF PG A P A + A P+ P+ + S Sbjct: 489 ----LQALPSP----PASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539 Query: 1678 GLCQAEGDSRPP---QDVCLPEP----SKQPGPQLDAGSLAKCSPDQELSFPK-NKEAAS 1729 + RPP D + P + PGP SP LS P ++S Sbjct: 540 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR----SPSSTLSGPDLAGHSSS 595 Query: 1730 SQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPL 1789 + + + LR GG P + PA + G AP LAF+ GAP Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP-----APPLAFR--GAPGA 648 Query: 1790 DATWPFGASPSHA--------AQG-HSAGRAGGHLH--PTAGRPGFEGNEFAPAGASSLT 1838 WP P A +G SA A G L P+ G G + A AGASS + Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 708 Query: 1839 APRGR 1843 + R Sbjct: 709 PKQAR 713 Score = 67.0 bits (162), Expect = 3e-10 Identities = 104/390 (26%), Positives = 130/390 (33%), Gaps = 69/390 (17%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-NTPATRTTKGAREAGGQAQAMEL 60 P P PPP L + + P P+ PPL TP+ + A A+ L Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP--------NALAVHL 396 Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120 +A PPS QAP S P P +P P QAP LA PP Sbjct: 397 LQAP-------FSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPP--- 444 Query: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF 180 P +P + + P P P PL+ P +A PA Sbjct: 445 --------------SPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPL 489 Query: 181 HRCFQEPPSSFTSTNYTSPSAT------PRPPAPGPPQSRG---TSPLQPGSYPEYQASG 231 + PP+SF SPSA+ PP PP P P + P QA Sbjct: 490 -QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548 Query: 232 ADSWP-PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPA 290 P P S P + P P P P SP + P A H +S P Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPP------PSRSPSS-TLSGPDLAGHSSSATSTPE 601 Query: 291 DVAGHAFTNGPLVFAFHQPQ-----GAWPEEAVGTGPAYPL-----PTQPAPSPLPCYQG 340 ++ G + +GP A P A A GPA PL P P P P G Sbjct: 602 ELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 659 Query: 341 QPGGLNRHSDLSG---ALSSPGAAHSAPRP 367 GL + G A +PGA P P Sbjct: 660 SADGLCTIYETEGPESATPAPGALDPGPSP 689 Score = 64.7 bits (156), Expect = 2e-09 Identities = 118/486 (24%), Positives = 164/486 (33%), Gaps = 94/486 (19%) Query: 3458 PGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPS 3517 PG RPPP P+ PA L + K P+ I G +P Sbjct: 30 PGSPRPPP----PVT-----PAALRVLGAAGAVGRK--------PLAERAGGIGGATIPE 72 Query: 3518 NHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGS------PGPLLQQALPLGA 3571 + P S PA+ GRG+ A P +SPG PGPL Q+ L + A Sbjct: 73 SAPRAGPTRTSRPPAS---GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129 Query: 3572 SLPRPGARGQDAEGKRAPLVFSGKRR-----APGARG-----------------RCAPDH 3609 ARG+ E + + +G RR PG R AP Sbjct: 130 E--ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187 Query: 3610 FQEDHLLQKEKEVSSS--HMVSEGGP---RGTFHKGSATKPAGCQSSSKDRSAASTPSKA 3664 K VSS+ H +E P R G +PA +S S + S+P+++ Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARS 246 Query: 3665 -------LKFPVHPR----KAVGSLAPGELARGTEN-----GMKPATPKAKPGPSSQGSG 3708 + P HP K + +L P ++ ++ G ++P A P PS+ S Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306 Query: 3709 SPRPGTKTGGGSQPQP--------ASGQLQSETATTPAKPSFPSRSPAPERLPARAQAK- 3759 S P +T P S LQ+ + P+ P P +P P+ PA A Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366 Query: 3760 SCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRT 3819 P + P + P+ + + P F S P P T Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426 Query: 3820 PRKQATPSRVLPTKPKPNSQNKPRPPPSEQR--------KAEPGHTQRKDRLGKAFPQGR 3871 P QA PS P Q P PP S +A P +L K PQ Sbjct: 427 PPSQAPPSLAAPPL-----QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481 Query: 3872 PLLRPP 3877 P L P Sbjct: 482 PALATP 487 Score = 64.7 bits (156), Expect = 2e-09 Identities = 94/377 (24%), Positives = 138/377 (36%), Gaps = 53/377 (14%) Query: 3523 PPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASL--PRPGARG 3580 PPP ++P + G +P E + G G + ++ P RP A G Sbjct: 35 PPPPVTPAALRVLGAAGAVG-----RKPLAERAGGIGGATIPESAPRAGPTRTSRPPASG 89 Query: 3581 QDAEGKRAPLVFSGKRRAPG---ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTF 3637 + G+RAP K +PG + GR A + L QK +S+ V+ Sbjct: 90 R---GERAP---PAKNTSPGPVSSPGR-ASGTTRPGPLGQKGLRISAEETVA-------- 134 Query: 3638 HKGSATK-PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP 3696 +G AT+ P S+ R S P+ P R++ A GTE G+ P Sbjct: 135 -RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS--------RAAGTEVGLPRPAP 185 Query: 3697 KAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA--TTPAKPSFPSRSPAPERLPA 3754 A+P P ++G ++P PA+ + S PA S S S P PA Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL-SSSATPLSSPA 244 Query: 3755 RAQAKSCTKGPREAG-EQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAP 3813 R+ GP G + P PK KG + + + P + ++G +P A Sbjct: 245 RS-------GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297 Query: 3814 DKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPL 3873 P P A PS L T P P P PPS+ + T + P PL Sbjct: 298 PSPSAPPSPSAPPS--LQTLPSP-----PATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350 Query: 3874 LRPPKRGTAVHGAEPAE 3890 PP + P + Sbjct: 351 ATPPPQAPPALALPPLQ 367 Score = 61.6 bits (148), Expect = 1e-08 Identities = 132/540 (24%), Positives = 171/540 (31%), Gaps = 79/540 (14%) Query: 876 PRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQT----PRPGDRGC---------PARG 922 PR P+ G P KS + + S P PAA P RP R PAR Sbjct: 189 PRPPTEG-PRKSVSSASEHSTTEPS-PAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246 Query: 923 RPKTRSLGLAPTEADAPS-QGRQQRRGKQLKLFRKDLDSG-GAAEGSGSGGGGRASGLRP 980 P R AP P +G Q R Q+ RKD G S ++ P Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306 Query: 981 RRNDGLGERPPPRPRRPRTQAPGSRADPA--------PRVPRAAALPEETRSSRRRRLPP 1032 L P P P P +QA S P P P + ++ LPP Sbjct: 307 SAPPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365 Query: 1033 RKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEK 1092 + P A L Q N L + + PPP P Sbjct: 366 LQAPPSPPASPPL--SPLATPSPQAPNALAVHLLQAPFS----PPPSPP----------- 408 Query: 1093 RKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLET 1152 V+ P P P +A A + P P SP A P ++ Sbjct: 409 ---VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA--- 462 Query: 1153 GAAAREGGPKCADRPSVAPKDPLQVPTNTET---SEETRPSLDFPQEAKEPETAEESAPD 1209 P A P K P Q P T P FP +A P + S P Sbjct: 463 -------PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA--PFSPSASLPM 513 Query: 1210 STEFTEALRSPPAACAGEMG------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHG 1263 S T ++PP A + ASP L P +PP DT P +LA Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573 Query: 1264 SSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISS 1323 P+ S L GP A S ++ P G P +++ P + + Sbjct: 574 PPPSRSPSSTLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA----- 626 Query: 1324 FGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAG-CFLEELHPKPSARDAPPA 1382 C PA ++R P P+A +G P GP G C + E SA AP A Sbjct: 627 --CHPAAWSRGP-APPLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGPESATPAPGA 682 Score = 57.8 bits (138), Expect = 2e-07 Identities = 194/790 (24%), Positives = 249/790 (31%), Gaps = 142/790 (17%) Query: 428 AAPGPPPARLPQLWD--PTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWP 485 AA P AR P L P +P P PP P AA R + G R L + A Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTP-AALRVL---GAAGAVGRKPLAERAGGIGG 67 Query: 486 QVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSP 545 +P + P G SR P A G + P + P SS G + Sbjct: 68 ATIPESAPRA-GPTRTSRPP--------------ASGRGERAPPAKNTSPGPVSSPGRA- 111 Query: 546 ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA-TNTAGST 604 +G T PG PL G ++S T + +P S L + A +T+G T Sbjct: 112 -----SGTTRPG--PL--GQKGLRISAEETVARGK---ATEAPKRSALSAGARRDTSGPT 159 Query: 605 CSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPE 664 + SP + + + E LP P PSA PPT E S HS +P Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRP-APSARPRPPT---EGPRKSVSSASEHSTT---EPS 212 Query: 665 PAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASL 724 PA A G A + L + P P +G PRA P +P+ +L Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA-PAHPSQPKPKGLQAL 271 Query: 725 DQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPP----GLPSPPAAP 780 V + L++ LA SP P LPSPPA P Sbjct: 272 RPPQVTPPRKDAAPALGPLSS---------SPLATPSPSAPPSPSAPPSLQTLPSPPATP 322 Query: 781 RVPADAHAG--LLSHAKTFLLAGDAQAEGKDDPLRTG--FLPSLAATPFP---LPASDLD 833 A G L +FL + P LP L A P P P S L Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382 Query: 834 MEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAG--- 890 ++L L +P + + F S P PS+ P ++ Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAA 437 Query: 891 ----VTPESKAPPPL-PAATPDPQTP-----------RPGDRGCPARGRPKTRSLGLAPT 934 V P A PP+ P+ATP PQ P +P + PA P ++L P Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP- 496 Query: 935 EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRP 994 A P Q +A S P L + PP P Sbjct: 497 -ASFPGQA----------------PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539 Query: 995 RRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELI--- 1051 P QAP R P P + + P T + P P R G +L Sbjct: 540 ASPTLQAP--RRPPTPGPDTSVSGPRLTLA----LAPGPPPPPSRSPSSTLSGPDLAGHS 593 Query: 1052 LKIVQQKNRLREYDFASESEEDEQPPP-------------RGP----GFRGRRGRGEKRK 1094 LR YD E PPP RGP FRG G Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG------ 647 Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGA 1154 L P E +G + PG PGP SP G + GA Sbjct: 648 -APLPWPPATGPGSADGLCTIYET--EGPESATPAPGALDPGP--SPGTSGGKAAAGAGA 702 Query: 1155 AAREGGPKCA 1164 A PK A Sbjct: 703 GASSRSPKQA 712 Score = 52.0 bits (123), Expect = 1e-05 Identities = 148/596 (24%), Positives = 179/596 (30%), Gaps = 118/596 (19%) Query: 3193 SSAVAHLLNSITEPAPKHHRG-------KRSAGKAAGSPGDPWGQEGEAKKDSPGERAKP 3245 SSA H S TEP+P R +R A ++ S P + P R P Sbjct: 201 SSASEH---STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA---RSGPSARGTP 254 Query: 3246 RARSTPSNPDG----AATPDSASATALADAGSPGP----PRTTPSPSPDPWAGGEPLLQA 3297 RA + PS P A P + A + GP P TPSPS P P LQ Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314 Query: 3298 TPVHEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLG 3357 P A PS+ G P H + SP L P+ P Sbjct: 315 LPSPPATP-PSQATTSLGS----PTLQATHSFLPSPPLSPLATPPPQAPPA--------- 360 Query: 3358 GAHGLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGR 3417 L P LQ P A + Q + HL + Sbjct: 361 -----LALPPLQAPP---------------SPPASPPLSPLATPSPQAPNALAVHLL--Q 398 Query: 3418 QPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAP----GPGEDRPPPRGSSPILS 3473 PF+ P +P +A P P AP P PP +SP +S Sbjct: 399 APFS-----PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453 Query: 3474 EGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA 3533 + P AP P L +P P P P PP S FP Sbjct: 454 PSATPP------PQAPPPLAAPPLQLAKP--PPQAPPALATPPLQALPSPPAS---FPGQ 502 Query: 3534 LADGRGDCALDGALERPENEASPGSPGPLLQ-----QALPLGASLPRPGARGQDAE--GK 3586 L P +A P PLLQ A P + RP G D G Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562 Query: 3587 RAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA 3646 R L + P +R S S +S GP H SAT Sbjct: 563 RLTLALAPGPPPPPSR--------------------SPSSTLS--GPDLAGHSSSATSTP 600 Query: 3647 ----GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGP 3702 G S + +AAS P A HP AP RG P P PG Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG- 659 Query: 3703 SSQG------SGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL 3752 S+ G + P T G P P+ G A A SRSP RL Sbjct: 660 SADGLCTIYETEGPESATPAPGALDPGPSPG-TSGGKAAAGAGAGASSRSPKQARL 714 Score = 51.6 bits (122), Expect = 2e-05 Identities = 186/763 (24%), Positives = 248/763 (32%), Gaps = 125/763 (16%) Query: 2014 SRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD 2073 +RA L +P PP P + L AA G+ GR P + G+ AT Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAA----GAVGRKPLAERAGGIGG---ATIP 71 Query: 2074 SPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133 AP G P P S P++SP RA G + R P Sbjct: 72 ESAPRAGPTRTSRP-PASGRGERAPPAKNTSPGPVSSPGRASG----------TTRPGPL 120 Query: 2134 PQQLLACSP----AWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQG 2189 Q+ L S A EA A + GA P T SP + + A G Sbjct: 121 GQKGLRISAEETVARGKATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEVG 179 Query: 2190 EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV 2249 P PP + P+ S E S E SP A P AG Sbjct: 180 LPRPAPSARPRPPT-----------EGPRKSVSSASEHSTTEP---SPA-ARRRPSAGGG 224 Query: 2250 SPSVAVRATGLSSTPTGDEAQAG---RGLPG-------PDPQSRGA--PPHTNPDRMPRG 2297 A R+ S+TP A++G RG P P P+ A PP P R Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284 Query: 2298 HSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGT--- 2354 + P +++ L A + P+ PP+LQ P PA + TS P T Sbjct: 285 -PALGPLSSSPLATPSPSAPPS-PSAPPSLQTL-PSPPATPPSQATTSLGSPTLQATHSF 341 Query: 2355 -PETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGP 2413 P S P P+ L L AP S P S + TP P P Sbjct: 342 LPSPPLSPLATPPPQAPPA--LALPPLQAPPSP--------PASPPLSPLATPS--PQAP 389 Query: 2414 QDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGA 2473 L P + Q P P ++ P L+ A + P Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA---APPLQVPPSP 446 Query: 2474 PAEP--SPAALPAQQPLEPLA----QKCQPPRKKSHRVS---------------GKERPN 2512 PA P SP+A P Q PLA Q +PP + ++ G+ + Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 506 Query: 2513 HSRGDPSHVTQPPPAQG----SKEVLRAPGSPHSQQL-----HPPSPTEHEVDVKTPASK 2563 S P PP Q + +L+ P SP + PP+P T S Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-----GPDTSVSG 561 Query: 2564 PRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPV 2623 PR A P R P D HS ++ +LRG E Sbjct: 562 PRLTLALAP--GPPPPPSRSPSSTLSGP--DLAGHSSSATSTPE-ELRGYDSGPEGGAAA 616 Query: 2624 SADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQ 2683 S ++ P A+++ P+ L+ G P A PP GPG +G + Sbjct: 617 SPPPDAELAACHP----AAWSRGPAPPLAFRGAPGAPLPWPP---ATGPGSADGLCTIYE 669 Query: 2684 EALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQ-KGASAR 2725 G A PG L PG G + G+ G GAS+R Sbjct: 670 ---TEGPESATPAPG--ALDPGPSPGTSGGKAAAGAGAGASSR 707 Score = 48.5 bits (114), Expect = 1e-04 Identities = 123/503 (24%), Positives = 162/503 (32%), Gaps = 84/503 (16%) Query: 3424 GVRRPGAPGQKARAL--EGTLPSKRRRVAMPGSAPGPGEDR----PPPRGSSPILSEGSL 3477 G RPG GQK + E T+ + A SA G R P P SP ++ S Sbjct: 113 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 172 Query: 3478 PALLHLCSEVAPSTTKGWPETLE--RPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALA 3535 A T G P RP P P + S H + P PAA Sbjct: 173 AA----------GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TTEPSPAA-- 215 Query: 3536 DGRGDCALDGALERPENEASPGSPGPLLQQAL--PLGASLPRPGARGQDAEGK-----RA 3588 R + G L+RP + + S PL A P PR A + K R Sbjct: 216 --RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 273 Query: 3589 PLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRG--TFHKGSATKPA 3646 P V ++ A A G + S S S P T AT P+ Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATP---------SPSAPPSPSAPPSLQTLPSPPATPPS 324 Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARG------TENGMKPATPKAKP 3700 +S + +T S P+ P AP LA + P +P A P Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384 Query: 3701 GPSS---------QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPER 3751 P + Q SP P P PAS + S +AT P++ PS + P + Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPV-SPSATPPSQAP-PSLAAPPLQ 441 Query: 3752 LPARAQAKSCTKGPREAGEQGPHGSLGP---------KEKGESSTKRKKGQVPGPARSES 3802 +P A Q P P + +T + PA Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501 Query: 3803 VGSFGRAPSAPDKPPRTPRKQATPS------RVLPTKPKPNSQNKPRPPPSEQRKAEPGH 3856 F + S P P TP QA P +V P+ P + PR PP+ P Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT----PGPDT 557 Query: 3857 TQRKDRLGKAFPQGRPLLRPPKR 3879 + RL A G P PP R Sbjct: 558 SVSGPRLTLALAPGPP--PPPSR 578 Score = 46.2 bits (108), Expect = 6e-04 Identities = 185/808 (22%), Positives = 244/808 (30%), Gaps = 143/808 (17%) Query: 1288 SKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQ- 1346 ++ P AR PG L P P + P P V + + G A R PL G Sbjct: 14 ARTPAARAPG-LLTP--RPPGSPRPPPPVTPAALRVLGAAGA-VGRKPLAERAGGIGGAT 69 Query: 1347 -PYSSPHSELFLGPKDLAGCFLEELHPKPSARD--APPASSSC---LCQDGEDAGSLEPQ 1400 P S+P + GP + P S R APPA ++ + G +G+ P Sbjct: 70 IPESAPRA----GPTRTS-------RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 118 Query: 1401 LPRSPPG---TAETEPGRAASPPTLESSSLFPDLPVDRFDPP--------LYGSLSANRD 1449 P G +AE R + + S+L D P S +A + Sbjct: 119 -PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177 Query: 1450 SGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPG 1509 GLP + PS P P P K +S T Sbjct: 178 VGLP--------RPAPSARPRP----------------PTEGPRKSVSSASEHSTTEPSP 213 Query: 1510 AAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRV 1569 AA P G G LS T L S + RG PR A Sbjct: 214 AARRRPSAGGGLQRPASRSLSSS-------ATPLSSPARSGPSARGTPRAPAHPSQPKPK 266 Query: 1570 ELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGT 1629 L PP + P S++ L S A ++ T+ + P T Sbjct: 267 GL-QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS----PPAT 321 Query: 1630 WPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPP 1689 P A+ G L A + P SP P Q A QA PP Sbjct: 322 PPSQATTSLGSPTLQ--ATHSFLPSPPLSPLAT----PPPQAPPALALPPLQA-----PP 370 Query: 1690 QDVCLP--EPSKQPGPQ---------LDAGSLAKCSPDQELSF------PKNKEAASSQE 1732 P P P PQ L A SP + F P + A + Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430 Query: 1733 SEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAP-DLAFQGDGAPPLDA 1791 + SL P + +P A P + P P + P LA APP A Sbjct: 431 APPSLAAPPLQ-----VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 485 Query: 1792 TWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVP 1851 T P A PS A G+A P+A P +P AP A L+ VP Sbjct: 486 TPPLQALPSPPAS--FPGQAP--FSPSASLP------MSPLATPPPQAPPVLAAPLLQVP 535 Query: 1852 SPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSG 1911 S P L P R P PG S G L P PP +PS Sbjct: 536 PSPPAS----------PTLQAPRRP---PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582 Query: 1912 LEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTAN 1971 GP +T + G+ G E G + Sbjct: 583 ----------TLSGPDLAGHSSSATSTPEELRGYDSGPEG----GAAASPPPDAELAACH 628 Query: 1972 QLQPENGVSPGGTDNHASVNASPKTALTGP--TEGAVLLEKCKGSRAAMSLQEEAEPTPS 2029 G +P A P TGP +G + + +G +A +P PS Sbjct: 629 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 688 Query: 2030 PPSPNRESLALALTAAHSRSGSEGRTPE 2057 P + ++ A A A SRS + R E Sbjct: 689 PGTSGGKAAAGAGAGASSRSPKQARLGE 716 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 94.7 bits (234), Expect = 2e-18 Identities = 299/1256 (23%), Positives = 394/1256 (31%), Gaps = 248/1256 (19%) Query: 1674 ASKTGLCQAEGDSRPPQDVC-LPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQE 1732 A+ +G +G P D+ + P PGPQ AG + K ++ A Sbjct: 94 ATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD----KGEKGAPGPR 149 Query: 1733 SEDSLRLLPCEQRGGFLPEPGTADQPHR----GAPAPEAFGSP-AVHLAPDLAFQGDGAP 1787 D EPGT P G P P G A +A + GA Sbjct: 150 GRDG--------------EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ 195 Query: 1788 PLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREA 1845 P G G + G GF+GN P G S PRG Sbjct: 196 LGVMQGPMGPMGPRGPPGPAGA---------PGPQGFQGNPGEPGEPGVSGPMGPRGPPG 246 Query: 1846 WLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPG----PGV-----------AKSKDG 1890 P P ++ + P PG PGV AK + G Sbjct: 247 ---PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 303 Query: 1891 ILGL--QELTPAAQ-SPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQL 1947 G+ + +P SP + P GL G G A+G+ G P G Sbjct: 304 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 363 Query: 1948 GLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVL 2007 G G G G+A T +G PE P G SP A G Sbjct: 364 GPGFPGAPGAKGEAGPTGARG------PEGAQGPRG---EPGTPGSPGPAGASGNPGTDG 414 Query: 2008 LEKCKGSRAAMSLQ-EEAEPTP-SPPSPNRESLALALTAAHSRSGSEGRTPERA--SSPG 2063 + KGS A + P P PP P + L G G E+ PG Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 474 Query: 2064 LNKPLLATG----DSPAPSVGDLAACAP-SPTSAAHMPCSLGPLPREDPLTSPSRAQGGL 2118 P A G + + G+ P P P + G P +D L P A G Sbjct: 475 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG-FPGQDGLAGPKGAPGER 533 Query: 2119 GGQLPASP-SCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCD 2177 G A P PG P L A G+ V P Sbjct: 534 GPSGLAGPKGANGDPG-------RPGEPGLPGARGLTGRPGDAGPQGKVGP--------- 577 Query: 2178 PKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESP 2237 G+P ED PPG A P P+ + E P Sbjct: 578 ------------SGAPGEDGRPGPPGPQGA------RGQPGVMGFPGPKGANGE-----P 614 Query: 2238 GRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGP-----DPQSRGAPPHTNPD 2292 G+A L G A GL P D G PGP + +GAP + Sbjct: 615 GKAGEKGLPG---------APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 665 Query: 2293 RMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPED- 2351 +P P G + G VP E GP GE G+ + Sbjct: 666 GLP------GPPGPPGEGGKPGD--QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 717 Query: 2352 ----PGTPET----GRSGATKMPRVTCPSTGL-------GLGRTTAPSSTASDFQSDSPQ 2396 PGTP T G SG P P GL G P D P+ Sbjct: 718 PRGLPGTPGTDGPKGASGPAGPPGAQGP-PGLQGMPGERGAAGIAGPKGDRGDVGEKGPE 776 Query: 2397 SHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSG 2456 P+GP PA NG+ P GP +A R Sbjct: 777 GAPGKDGGRGLTGPIGPPG-----------PAGA-NGEKGEVGPPGPAG----SAGARGA 820 Query: 2457 PGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRG 2516 PG R PG P Q + ++ + +K G + P+ + G Sbjct: 821 PG-----ERGETGPPGPAGFAGPPGADGQPGAK--GEQGEAGQKGDAGAPGPQGPSGAPG 873 Query: 2517 --DPSHVTQPPPAQGSKEVLRAPGSPHSQ-QLHPPSPTEH--EVDVKTPASKPRPDQARE 2571 P+ VT P A+G++ A G P + ++ PP + P+ K P AR Sbjct: 874 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG 933 Query: 2572 DELHPKQAEK--REGRRW----RREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSA 2625 D P +A + +G + EP D PS +EG + L G+R I+ + Sbjct: 934 DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ--GLAGQR----GIVGLPG 987 Query: 2626 DVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEA 2685 RG R P + + P +G P A G++ P PG+ A E +E Sbjct: 988 Q-----RGERGFPGLPGPSGEPGK----QGAPGASGDRGPPGPVGPPGLTGPAGEPGRE- 1037 Query: 2686 LCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGA-SARGFWGP-------RETKALG 2737 G GA PPG DGAA + G+ GA A G GP T G Sbjct: 1038 ---GSPGADGPPG--------RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086 Query: 2738 VCKESGSE-PAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTS-----SCLQ 2791 E+G++ P S A +R +G P GP G + P + + LQ Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQG-------PQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1139 Query: 2792 GLPDNPDTQG--GVQGPEGPT-----PDASGSSAKDPPSLFDDEVSFSQLFPPGGR 2840 GLP P G G GP GP+ P G S KD + + PPG R Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG-----PPGPR 1190 Score = 92.8 bits (229), Expect = 6e-18 Identities = 306/1227 (24%), Positives = 381/1227 (31%), Gaps = 267/1227 (21%) Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP--PAAENSFPGANFGVPPAEPEPIPKGSRPG 265 PGP +G +PG + P PA E P + G + P P+G R G Sbjct: 100 PGPKGQKG----EPGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGDKGEKGAPGPRG-RDG 153 Query: 266 --GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGT--- 320 G+P P G P P + G+ FA Q G + E+A G Sbjct: 154 EPGTPGN-------PGPPGPPGPPGPPGLGGN--------FAA-QMAGGFDEKAGGAQLG 197 Query: 321 ---GPAYPL----PTQPAPSPLPC-YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372 GP P+ P PA +P P +QG PG +SG + G +P D Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG-VSGPMGPRGPPGPPGKPGDDGE 256 Query: 373 HKSLTKILPERPPSAQDGLG--STRGPPSSLPQRHFPGQ-----AYRASGVDTSPGPPDT 425 K PP Q G T G P R +PG A GV G P Sbjct: 257 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG- 315 Query: 426 ELAAPGPP-PARLPQLWDPTAA------------PYPTPPGGPLAATRSMFFNGQPSPGQ 472 E +PGP P LP T P P P GP+ F G P + Sbjct: 316 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG-AK 374 Query: 473 RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--------GSQGALGTA 524 P A P P P G P PAG G GS GA G A Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGS------PGPAGASGNPGTDGIPGAKGSAGAPGIA 428 Query: 525 GKT--PGPREKL-------PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPH-- 573 G PGPR P Q G P + + G P +P G A PQ +P Sbjct: 429 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP---GPAGPQGAPGPA 485 Query: 574 -------------GTPSLPPPRVVGAS-----PSESPLPSPA--------TNTAGSTCSS 607 G + PP GA P + L P + AG ++ Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 545 Query: 608 LSP-MSSSPANPSSEE-SQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEP 665 P P P + + PG GP P P E G P PP QP Sbjct: 546 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP----GPPGPQGARGQPG- 600 Query: 666 AKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFP-------RAPPPYPTHHFS 718 FP P GA G E P G GL+G P A PP P Sbjct: 601 VMGFPGPK---GANGEPGKAGEKGLP------GAPGLRGLPGKDGETGAAGPPGP----- 646 Query: 719 LSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPA 778 A R G A G Q PGPPG P Sbjct: 647 -------------------------AGPAGERGEQG---APGPSGFQGLPGPPGPPGEGG 678 Query: 779 APR---VPADAHA-GLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDM 834 P VP +A A GL+ G+ + G LP T P AS Sbjct: 679 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 738 Query: 835 EDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPE 894 A+ L GM + I D G +GP G+T Sbjct: 739 PPGAQGPP----GLQGMPGERGAAGIAGPK----GDRGDVGEKGPEGAPGKDGGRGLTGP 790 Query: 895 SKAPPPLPAATPDPQTPRPGDRGCP-ARGRP----KTRSLGLAPTEADAPSQGRQQRRGK 949 P P A + PG G ARG P +T G A + G+ +G+ Sbjct: 791 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850 Query: 950 QLKLFRK-DLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRP----RTQAPGS 1004 Q + +K D + G SG+ G +G+ + + PP P R PGS Sbjct: 851 QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 910 Query: 1005 RADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREY 1064 +P P P + + + +R PP R G G + +K Sbjct: 911 NGNPGPPGPPGPSGKDGPKGARGDSGPP--------GRAGEPGLQGPAGPPGEKG----- 957 Query: 1065 DFASESEEDEQPPPRGPGFRGRRG-------RGEKRKEVELTQGPREDEPQKPRKAARQE 1117 + + + PP G G+RG RGE+ GP + P K Sbjct: 958 EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERG--FPGLPGPSGE----PGKQGAPG 1011 Query: 1118 AGGDGAPANPEEPGG-----SRPGPGRSPQARGP----------SRSLETGAAAREGGP- 1161 A GD P P P G PG SP A GP ETGA G P Sbjct: 1012 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1071 Query: 1162 ------------KCADRPSVAPKDPL--QVPTNTETSEETRPSLDFPQEAKEPETAEESA 1207 K DR + P+ P + + EA EP E Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP--GERGL 1129 Query: 1208 PDSTEFT--EALRSPPAACAGEMGAS--PGLLIPEQPP----PSRHD--------TGTPK 1251 FT + L PP +G+ GAS G P PP PS D G P Sbjct: 1130 KGHRGFTGLQGLPGPPGP-SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188 Query: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPG 1278 P G T P G PG G PG Sbjct: 1189 PRGRSGETGPAGPPGNPGPPGPPGPPG 1215 Score = 90.1 bits (222), Expect = 4e-17 Identities = 211/804 (26%), Positives = 258/804 (32%), Gaps = 117/804 (14%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGG-QAQAME- 59 PG R R P T P PG P P L N A +AGG Q M+ Sbjct: 146 PGPRGRDGEPGTPGNPGPP----GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 201 Query: 60 ---------------LPEAQPRQARDGELKPPSLRG-QAPSSTPGKRGSPQTP-----PG 98 P Q Q GE P + G P PG G P PG Sbjct: 202 PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG 261 Query: 99 RSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGT 158 ++ + P G A G P + G+ R P LD + E +P G+ Sbjct: 262 KAGERGPPGPQG-ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK-GESGSPGENGS 319 Query: 159 GAPLRP-GLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPR-PPAPG------P 210 P+ P GLP + R P P+ P P APG P Sbjct: 320 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379 Query: 211 PQSRGTSPLQ-----PGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPI-P 259 +RG Q PG+ +GA P P A+ S P P P P Sbjct: 380 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439 Query: 260 KGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG 319 G + P G Q P + G + P G A G A + + E G Sbjct: 440 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 499 Query: 320 TGPAYPLPTQPAPSPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHK 374 GP P + AP + GQ G G SG GA RP L Sbjct: 500 VGPIGPPGERGAPGNRG-FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558 Query: 375 SLTKILPERP----------PSAQDGLGSTRGPPSSLPQRHFPGQAY--RASGVDTSPGP 422 + + L RP PS G GPP R PG G + PG Sbjct: 559 A--RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 616 Query: 423 PDTELAAPGPPPAR-LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAP 481 E PG P R LP T A P P GP G PS Q L P P Sbjct: 617 AG-EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG-PSGFQGLPGPPGPP 674 Query: 482 ----LPWPQVLPTARPSPHGMEMLSRLPFPA--GGPEWQG--GSQGALGTAGKTPGPREK 533 P Q +P +P + FP G P QG G +G GT G T GP+ Sbjct: 675 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG-TDGPKGA 733 Query: 534 L-PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQP--------QVSPHGTPSLPPPRVV 584 PA G P L GM PG + G+A P + P G P R + Sbjct: 734 SGPAGPPGAQGPPGL---QGM--PGERGAA-GIAGPKGDRGDVGEKGPEGAPGKDGGRGL 787 Query: 585 GASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQET 644 P P P+ A G P S+ A + E GP GP+ F PP + Sbjct: 788 -TGPIGPPGPAGANGEKGEV-GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP 845 Query: 645 GSP-------------FPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691 G+ P P+ P P P+ P GA+G T FP Sbjct: 846 GAKGEQGEAGQKGDAGAPGPQGPSGAPG---PQGPTGVTGPKGARGAQGPPGA---TGFP 899 Query: 692 HEGPEVGRGGLQGFPRAP-PPYPT 714 VG G G P P PP P+ Sbjct: 900 GAAGRVGPPGSNGNPGPPGPPGPS 923 Score = 83.6 bits (205), Expect = 4e-15 Identities = 216/837 (25%), Positives = 264/837 (31%), Gaps = 149/837 (17%) Query: 6 PRGAPPPT-MTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQ 64 PRG P P TG L P+ PG + +G + G A P Sbjct: 436 PRGPPGPQGATGPLGPKGQTGEPG----------IAGFKGEQGPKGEPGPAGPQGAPGPA 485 Query: 65 PRQARDGELKPPSLRGQAPSSTPGKRGSPQTP--PGRSPLQAPSRLAGRAEGSPPQRYIL 122 + + G P G P PG+RG+P PG+ L P +G+P +R Sbjct: 486 GEEGKRGARGEPG--GVGPIGPPGERGAPGNRGFPGQDGLAGP-------KGAPGERGPS 536 Query: 123 GIASSRTKPTLDETPENPQLEAAQ----LPEVDTPQGP--GTGAPLRPGLPRTEAQPAAE 176 G+A + P P L A+ P PQG +GAP G P A Sbjct: 537 GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 596 Query: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236 F P + P PG P RG PG E A+G Sbjct: 597 GQPGVMGFPGPKGA-----NGEPGKAGEKGLPGAPGLRGL----PGKDGETGAAGPPGPA 647 Query: 237 -PAAENSFPGA----NFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGA-STKPFPA 290 PA E GA F P P P +G +PG +GV + P L G + FP Sbjct: 648 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD--QGVPGEAGAPGLVGPRGERGFPG 705 Query: 291 DVA--GHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLN 346 + G GP P P+ A +GPA P P P QG PG G Sbjct: 706 ERGSPGAQGLQGPRGLP-GTPGTDGPKGA--SGPAGP----PGAQGPPGLQGMPGERGAA 758 Query: 347 RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-----------PSAQDGLGSTR 395 + G G P D I P P P G R Sbjct: 759 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818 Query: 396 GPPSSLPQRHFPGQAYRAS--GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYP---- 449 G P + PG A A G D PG + A A P P+ AP P Sbjct: 819 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878 Query: 450 --TPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP--TARPSPHGMEMLSRLP 505 T P G A G P R+ P S P P P + + P G S P Sbjct: 879 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938 Query: 506 FPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTD-PGAQPLFFG 564 AG P G QG G G+ P + P+ G L G+ PG Sbjct: 939 GRAGEP----GLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPG------- 987 Query: 565 VAQPQVSPHGTPSLPPPR-------VVGASPSESPLPSPA-----TNTAGSTCSSLSPMS 612 Q G P LP P GAS P P P T AG SP + Sbjct: 988 ----QRGERGFPGLPGPSGEPGKQGAPGASGDRGP-PGPVGPPGLTGPAGEPGREGSPGA 1042 Query: 613 SSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAF--- 669 P + G G + P P GSP P+ PT Q + +A Sbjct: 1043 DGPPGRDGAAG-VKGDRGETGAVGAPGAPGPPGSPGPAG------PTGKQGDRGEAGAQG 1095 Query: 670 ------PFPADGL-GAEGAFQCLEETPFPHE-GPEVGRG--GLQGFPRAPPPYPTHHFSL 719 P A G+ G +G E P E G + RG GLQG P P P Sbjct: 1096 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGP-------- 1147 Query: 720 SSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSP 776 D+ S A R G + KDG PGP G P P Sbjct: 1148 ---------------SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189 Score = 76.6 bits (187), Expect = 4e-13 Identities = 256/1081 (23%), Positives = 319/1081 (29%), Gaps = 221/1081 (20%) Query: 425 TELAAPGPP-----PARLPQLWDPTAAPYPTPPGG---PLAATRSMFFNGQPSPGQRLCL 476 T PGP P + + P P P P G P G P P R Sbjct: 95 TASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGE 154 Query: 477 PQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPA 536 P + P P P P P G+ G E GG+Q LG GP P Sbjct: 155 PGTPGNPGPPG-PPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ--LGVMQGPMGPMG--PR 209 Query: 537 VRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSP 596 G+P + G +P GV+ P + P G P PP G E+ P Sbjct: 210 GPPGPAGAPGPQGFQGNPGEPGEP---GVSGP-MGPRGPPG--PPGKPG-DDGEAGKPGK 262 Query: 597 ATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPSAFFHPPTHPQETGSP----FPSP 651 A +P P + + PG G P E+GSP P P Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322 Query: 652 EPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGP-EVGRGGLQGFPRAPP 710 P LP + PA GA G + P P P VG G GFP AP Sbjct: 323 MGPRGLPGE------RGRTGPAGAAGARGN----DGQPGPAGPPGPVGPAGGPGFPGAP- 371 Query: 711 PYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGP 770 + G AR +G Q G Sbjct: 372 -------------------------------------GAKGEAGPTGARGPEGAQGPRGE 394 Query: 771 PGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP-FPLPA 829 PG P P PA A +G+ +G + P +A P FP P Sbjct: 395 PGTPGSPG----PAGA-------------SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437 Query: 830 SDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKA 889 + T L G + Q+ P I + EP GP GP + Sbjct: 438 GPPGPQG-------ATGPL-GPKGQTGEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEE 488 Query: 890 GVTPESKAPPPLPAATPDPQTPRPGDRGCPA-------RGRPKTRS-LGLAPTEADAPSQ 941 G P + P + PG+RG P +G P R GLA + Sbjct: 489 GKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 548 Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERP-PPRPRRPRTQ 1000 GR G G G G + P G RP PP P+ R Q Sbjct: 549 GRPGEPGLP----------GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598 Query: 1001 APGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNR 1060 PG P P+ E + + LP R + G G Sbjct: 599 -PGVMGFPGPKGANG-----EPGKAGEKGLPGAPGLRGLPGKDGETGAA---------GP 643 Query: 1061 LREYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQ--------GPREDEPQ 1108 A E E P P G PG G G G K + + GPR + Sbjct: 644 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703 Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRP----GPGRSPQARGP----SRSLETGAAAREGG 1160 + + G G P PG P GP P A+GP E GAA G Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI-AG 762 Query: 1161 PKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSP 1220 PK DR V K P P T P E E P A +P Sbjct: 763 PK-GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 821 Query: 1221 ----------PAACAGEMGA--------------------SPGLLIPEQPPPSRHDTGTP 1250 PA AG GA +PG P P + TG Sbjct: 822 GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVT 881 Query: 1251 KPSGSLANTAPHGSSPTPGVGSLLGGPG-----GTQAPVSHNSKDPPARQPGEFLAPVAN 1305 P G+ P G++ PG +G PG G P + KD P G+ P Sbjct: 882 GPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-SGPPGR 940 Query: 1306 PSSTACPKPSVLSSKISSFGCD-PAGFNRDPLGVPVAKKGPQPYSSPHSELFL----GPK 1360 P+ + G D P+G P GPQ + + L G + Sbjct: 941 AGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP--------GPQGLAGQRGIVGLPGQRGER 992 Query: 1361 DLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTA--ETEPGRAAS 1418 G L +P + AP AS G P P PPG EPGR S Sbjct: 993 GFPG--LPGPSGEPGKQGAPGAS-----------GDRGPPGPVGPPGLTGPAGEPGREGS 1039 Query: 1419 P 1419 P Sbjct: 1040 P 1040 Score = 73.9 bits (180), Expect = 3e-12 Identities = 261/1086 (24%), Positives = 342/1086 (31%), Gaps = 209/1086 (19%) Query: 455 PLAATRSMFFNGQPSP-GQR--------LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLP 505 P+ T +GQP P GQ+ + P+ P P P P G + + Sbjct: 87 PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQG---PAGEQGPRG-DRGDKGE 142 Query: 506 FPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDP--GAQPLFF 563 A GP + G G G G PGP P GG+ A G + GAQ Sbjct: 143 KGAPGPRGRDGEPGTPGNPGP-PGPPG--PPGPPGLGGNFAAQMAGGFDEKAGGAQ---L 196 Query: 564 GVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623 GV Q + P G P PP P+ +P P +P P E Sbjct: 197 GVMQGPMGPMG-PRGPP------GPAGAPGPQG--------------FQGNPGEPG--EP 233 Query: 624 QLPGPLGPSAFFHPPTHPQ---ETGSPFPSPE--PPHSLPTHYQPEPAKAFPFPADGLGA 678 + GP+GP PP P E G P + E PP P+ A+ FP G Sbjct: 234 GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG-------PQGARGFPGTPGLPGV 286 Query: 679 EG--AFQCLEETPFPHEGPEV-GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQ 735 +G + L+ P V G G G +P P Sbjct: 287 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR-------------------- 326 Query: 736 CDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAK 795 L G AR DG GPPG P P P A Sbjct: 327 ------GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK------ 374 Query: 796 TFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQS 855 AG A G + P +P P AS + T+ + G + + Sbjct: 375 --GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS----------GNPGTDGIPGAKGSA 422 Query: 856 DNPEIDSS--FIDVFADEEPSGPRGP-----SSGHP----LKSKAGVTPESKAPPPLPAA 904 P I + F P G GP +G P K + G P+ + P P Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG--PKGEPGPAGPQG 480 Query: 905 TPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAA 964 P P G RG ARG P P E AP G + G+ G A Sbjct: 481 APGP-AGEEGKRG--ARGEPGGVGPIGPPGERGAP--GNRGFPGQD-----------GLA 524 Query: 965 EGSGSGGGGRASGLR-PRRNDGLGERPPPRPRRPRTQ-APGSRADPAPRVPRAAALPEET 1022 G+ G SGL P+ +G P RP P A G P P+ P Sbjct: 525 GPKGAPGERGPSGLAGPKGANG----DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGA 580 Query: 1023 RSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPG 1082 R PP GA G+ ++ K E + E+ P PG Sbjct: 581 PGEDGRPGPPGPQ--------GARGQPGVMGFPGPKGANGE-----PGKAGEKGLPGAPG 627 Query: 1083 FRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPG-GSRPG----P 1137 RG G+ + GP ++ + A +G G P P PG G +PG P Sbjct: 628 LRGLPGK-DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 686 Query: 1138 GR--SPQARGPSRSL----ETGAAAREG--------------GPKCADRPSVAPKDPLQV 1177 G +P GP E G+ +G GPK A P+ P Q Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP--GAQG 744 Query: 1178 PTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIP 1237 P + R + + E P+ + R G +G PG P Sbjct: 745 PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR----GLTGPIG-PPG---P 796 Query: 1238 EQPPPSRHDTGTPKPSGSL-ANTAP--HGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPAR 1294 + + G P P+GS A AP G + PG G PG P + A Sbjct: 797 AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAG 855 Query: 1295 QPGEFLAP-VANPSSTACPK-PSVLSSKISSFGCD-PAGFNRDP-----LGVPVAKKGPQ 1346 Q G+ AP PS P+ P+ ++ + G P G P +G P + P Sbjct: 856 QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 915 Query: 1347 PYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGE--DAGSLEPQLPRS 1404 P P GPK G P R P GE + G P Sbjct: 916 PPGPPGPSGKDGPKGARG------DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969 Query: 1405 PPGTAETEPGRA-ASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKT 1463 PPG R P FP LP +P G+ A+ D G P PP T Sbjct: 970 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPP-GPVGPPGLT 1028 Query: 1464 VPSDPP 1469 P+ P Sbjct: 1029 GPAGEP 1034 Score = 72.0 bits (175), Expect = 1e-11 Identities = 265/1132 (23%), Positives = 348/1132 (30%), Gaps = 234/1132 (20%) Query: 6 PRGAPPPTMTGDLQPRQVASSPGHPSQP----PLEDNTPATRTTKGAR--EAGGQAQAME 59 PRG P P G P+ +PG P +P P+ P K EAG +A E Sbjct: 208 PRGPPGPA--GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 265 Query: 60 LPEAQPRQARD-----------------------GELKPPSLRGQAPSSTPGKRGSP--- 93 P+ AR GE P ++G+ S +PG+ GSP Sbjct: 266 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE--SGSPGENGSPGPM 323 Query: 94 --QTPPGRSPLQAPSRLAGRAEGSPPQRYILGI-----------------ASSRTKPTLD 134 + PG P+ AG A G+ Q G A PT Sbjct: 324 GPRGLPGERGRTGPAGAAG-ARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 382 Query: 135 ETPENPQLEAAQLPEVDTPQGPG----TGAPLRPGLPRTEAQPAAEELGFHRCF---QEP 187 PE Q E TP PG +G P G+P + A + F + P Sbjct: 383 RGPEGAQ---GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439 Query: 188 PSSFTSTNYTSPSATPRPPA-------------PGPPQSRGTSPLQPGSYPEYQASGADS 234 P +T P P PGP +G PG E GA Sbjct: 440 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA----PGPAGEEGKRGARG 495 Query: 235 WP-------PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287 P P E PG N G P + PKG+ P G++ +G +P Sbjct: 496 EPGGVGPIGPPGERGAPG-NRGFPGQDGLAGPKGAPGERGPSGLAGP---KGANGDPGRP 551 Query: 288 FPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG---- 343 + G G +P A P+ VG A +P P +GQPG Sbjct: 552 GEPGLPGARGLTG-------RPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604 Query: 344 ----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-----------PSAQ 388 G N +G PGA P D + P P PS Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664 Query: 389 DGLGSTRGPPSSLPQ---RHFPGQAYRASGVDTSPGPPDT-----ELAAPGPP----PAR 436 GL GPP + + PG+A G GP E +PG P Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPGEA----GAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720 Query: 437 LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQR----LCLPQSAPLPWPQVLPTAR 492 LP + P GP A G P G+R + P+ + P Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP--GERGAAGIAGPKGDRGDVGEKGPEGA 778 Query: 493 PSPHGMEMLSRL---PFPAG--GPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547 P G L+ P PAG G + + G G G+AG P E+ + G P Sbjct: 779 PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER------GETGPPGP 832 Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPS-ESPL----PSPATNTAG 602 + G QP G Q + G P P+ +P + P P A G Sbjct: 833 AGFAGPPGADGQPGAKG-EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 891 Query: 603 STCSSLSPMSSSPANP--SSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEP---PHSL 657 ++ P ++ P S+ PGP GPS P ++G P + EP + Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 951 Query: 658 PTHYQPEPAKAFPFPADG----------LGAEGAFQCLEETPFPHEGPEVGRGGLQGFPR 707 P + EP P A+G G G E FP G G QG P Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 1011 Query: 708 AP----PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDG 763 A PP P L+ + + R S A R G + G Sbjct: 1012 ASGDRGPPGPVGPPGLTGPA----------GEPGREGSPGADGPPGRD--GAAGVKGDRG 1059 Query: 764 HQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAAT 823 + G PG P PP +P PA GD G P+ PS A Sbjct: 1060 ETGAVGAPGAPGPPGSPG-PAGPTG----------KQGDRGEAGAQGPMG----PSGPAG 1104 Query: 824 PFPLPASDLDMEDDAKLDSLITEALNGME-----YQSDNPEIDSSFIDVFADEEPSGPRG 878 + D + L G P S PSGPRG Sbjct: 1105 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1164 Query: 879 PSSGHPLKSKAGVT----------PESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRS 928 P K G P ++ PA P P PG G P G + Sbjct: 1165 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP-PGPPGPPGPGIDMSAF 1223 Query: 929 LGLAPTE----------ADAPSQGRQQRRGK---QLKLFRKDLDSGGAAEGS 967 GL P E AD + G +Q + LK ++S + EGS Sbjct: 1224 AGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGS 1275 Score = 63.9 bits (154), Expect = 3e-09 Identities = 123/507 (24%), Positives = 162/507 (31%), Gaps = 66/507 (13%) Query: 3414 RGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473 +G P F+G+ PG PG EG P + +PG A PG PRG Sbjct: 656 QGAPGPSGFQGL--PGPPGPPG---EGGKPGDQ---GVPGEAGAPG--LVGPRGERGFPG 705 Query: 3474 EGSLPALLHLCSEVAPSTTKGW--PETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFP 3531 E P L T G P+ P P G + P Q P + Sbjct: 706 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP-----GAQGPPGLQGMPGERGAAGI 760 Query: 3532 AALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAE-GKRAP 3589 A RGD G P + G GP+ P P GA G+ E G P Sbjct: 761 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI---------GPPGPAGANGEKGEVGPPGP 811 Query: 3590 LVFSGKRRAPGARGRCA----------PDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHK 3639 +G R APG RG P + ++ E GP+G Sbjct: 812 AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 871 Query: 3640 GSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAK 3699 P G + K A P A FP A G + P + G P P K Sbjct: 872 PGPQGPTGV-TGPKGARGAQGPPGATGFP----GAAGRVGPPG-SNGNPGPPGPPGPSGK 925 Query: 3700 PGPSSQGSGSPRPGTKTGGGSQ-PQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQA 3758 GP S PG G Q P G+ P+ P P P+ L A Sbjct: 926 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP---PGPQGL---AGQ 979 Query: 3759 KSCTKGPREAGEQGPHGSLGPKEK-------GESSTKRKKGQVPGPARSESVGSFGR--A 3809 + P + GE+G G GP + G S + G V P + G GR + Sbjct: 980 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 1039 Query: 3810 PSAPDKPPRTPRKQATPSR----VLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGK 3865 P A P R R + P P P ++ + G + +G Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099 Query: 3866 AFPQGRPLLRPPK--RGTAVHGAEPAE 3890 + P G ++ P+ RG EP E Sbjct: 1100 SGPAGARGIQGPQGPRGDKGEAGEPGE 1126 Score = 61.2 bits (147), Expect = 2e-08 Identities = 170/653 (26%), Positives = 209/653 (32%), Gaps = 138/653 (21%) Query: 2 PGER--PRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-----NTPATRTTKGAREAGGQ 54 PG++ P A P + G R G P L+ TP T KGA G Sbjct: 680 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739 Query: 55 AQAMELPEAQPRQARDGELK---PPSLRG----QAPSSTPGKRGS-----PQTPPGRSPL 102 A P Q G P RG + P PGK G P PPG Sbjct: 740 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG---- 795 Query: 103 QAPSRLAG-RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAP 161 P+ G + E PP G A +R P + E P G P Sbjct: 796 --PAGANGEKGEVGPPGP--AGSAGARGAP-------------GERGETGPPGPAGFAGP 838 Query: 162 LRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAP----GPPQSRGT 216 P + QP A+ E G Q+ + PS P P P GP +RG Sbjct: 839 -----PGADGQPGAKGEQG--EAGQKGDAGAPGPQ--GPSGAPGPQGPTGVTGPKGARGA 889 Query: 217 SPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPI----PKGSRPGGSPRGVS 272 PG+ A+G P N PG PP P P PKG+R P G + Sbjct: 890 QG-PPGATGFPGAAGRVG--PPGSNGNPG-----PPGPPGPSGKDGPKGARGDSGPPGRA 941 Query: 273 FQFPFPALHGASTKPF----PADVAGHAFTNGPLVFAFHQPQGAWPEEAV----GTGPAY 324 + P L G + P P D G + GP PQG + + G Sbjct: 942 GE---PGLQGPAGPPGEKGEPGD-DGPSGAEGP-----PGPQGLAGQRGIVGLPGQRGER 992 Query: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384 P P PS P QG PG G + PG A P + + + P Sbjct: 993 GFPGLPGPSGEPGKQGAPGASGDRGP-PGPVGPPGLTGPAGEPGREGSPGA------DGP 1045 Query: 385 PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP-PARLPQLWDP 443 P +DG +G PG +PGPP +PGP P Sbjct: 1046 PG-RDGAAGVKGDRGETGAVGAPG----------APGPP----GSPGPAGPTGKQGDRGE 1090 Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503 A P P GP A G P A P + L R G L Sbjct: 1091 AGAQGPMGPSGPAGA------RGIQGPQGPRGDKGEAGEPGERGLKGHR----GFTGLQG 1140 Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPR-EKLPAVRSSQGGSPALFTYNGMTDPGAQPLF 562 LP GP G QGA G AG + GPR P S + G+ NG+ P P Sbjct: 1141 LP----GPPGPSGDQGASGPAGPS-GPRGPPGPVGPSGKDGA------NGIPGPIGPPGP 1189 Query: 563 FGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSP 615 G + P G P P P P P P + S + L P P Sbjct: 1190 RG-RSGETGPAGPPGNPGP------PGPPGPPGPGIDM--SAFAGLGPREKGP 1233 Score = 55.1 bits (131), Expect = 1e-06 Identities = 117/479 (24%), Positives = 144/479 (30%), Gaps = 72/479 (15%) Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488 G G + E P R R PG+ PG PP P L + E A Sbjct: 132 GPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKA 191 Query: 3489 PSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECP-----PPSLSPF-PAALADGRGDC 3541 G + P+ P P G P Q P P P P G Sbjct: 192 GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP 251 Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR-PGARG----QDAEGKRAPLVFSGKR 3596 DG +P G PGP + P LP G RG A+G+ G+ Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311 Query: 3597 RAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGC-------- 3648 +PG G P GPRG + T PAG Sbjct: 312 GSPGENGSPGP-----------------------MGPRGLPGERGRTGPAGAAGARGNDG 348 Query: 3649 QSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSG 3708 Q P+ FP P A G P ARG E P PG Sbjct: 349 QPGPAGPPGPVGPAGGPGFPGAP-GAKGEAGPTG-ARGPEGAQGPRGEPGTPGSPGPAGA 406 Query: 3709 SPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREA 3768 S PGT G++ + + A P P P P P+ K T P A Sbjct: 407 SGNPGTDGIPGAKGSAGAPGI----AGAPGFPG-PRGPPGPQGATGPLGPKGQTGEPGIA 461 Query: 3769 ---GEQGPHGSLGPK----EKGESSTKRKKGQVPGPARSESVGSFGR--APSAPDKP--- 3816 GEQGP G GP G + + K+G P +G G AP P Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 521 Query: 3817 ----PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGR 3871 P+ + PS + K +P P PG R G A PQG+ Sbjct: 522 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP------GLPGARGLTGRPGDAGPQGK 574 Score = 54.3 bits (129), Expect = 2e-06 Identities = 116/469 (24%), Positives = 154/469 (32%), Gaps = 56/469 (11%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG G LP +R R G+A G D P P V Sbjct: 314 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPP--------------GPV 359 Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA- 3546 P+ G+P + RG E + P SP PA + G + GA Sbjct: 360 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 419 Query: 3547 --LERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFS-GKRRAPGARG 3603 P +PG PGP P GA+ P G +GQ E A G + PG G Sbjct: 420 GSAGAPGIAGAPGFPGPRGPPG-PQGATGPL-GPKGQTGEPGIAGFKGEQGPKGEPGPAG 477 Query: 3604 -RCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP-----AGCQSSSKDR-- 3655 + AP E+ E + G RG G+ P AG + + +R Sbjct: 478 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA--PGNRGFPGQDGLAGPKGAPGERGP 535 Query: 3656 SAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTK 3715 S + P A P P + PG ARG A P+ K GPS RPG Sbjct: 536 SGLAGPKGANGDPGRPGEPG---LPG--ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP- 589 Query: 3716 TGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP---REAGEQG 3772 PQ A GQ P FP A P +A K P G+ G Sbjct: 590 ----PGPQGARGQ--------PGVMGFPGPKGANGE-PGKAGEKGLPGAPGLRGLPGKDG 636 Query: 3773 PHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP--PRTPRKQATPSRVL 3830 G+ GP + +R + PGP+ + + P KP P + P V Sbjct: 637 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 696 Query: 3831 PTKPK--PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPP 3877 P + P + P + + PG G + P G P + P Sbjct: 697 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 745 Score = 46.2 bits (108), Expect = 6e-04 Identities = 107/391 (27%), Positives = 128/391 (32%), Gaps = 65/391 (16%) Query: 3415 GGRQPFAFRGVRRP-GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473 G P GV P GA G + P RV PGS PG PP P Sbjct: 870 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP----GPSGK 925 Query: 3474 EGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA 3533 +G A + P G P L+ P P + + E PP P Sbjct: 926 DGPKGAR----GDSGPPGRAGEPG-LQGPAGPPGEKGEPGDDGPSGAEGPPG-----PQG 975 Query: 3534 LADGRGDCALDGALERPENEASPGSPGPLLQ---QALPLGASLPR--PGARGQDAEGKRA 3588 LA RG L G +R E PG PGP + Q P GAS R PG G G Sbjct: 976 LAGQRGIVGLPG--QRGER-GFPGLPGPSGEPGKQGAP-GASGDRGPPGPVGPP--GLTG 1029 Query: 3589 PLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGC 3648 P G+ +PGA G P + E + GP G+ PAG Sbjct: 1030 PAGEPGREGSPGADG--PPGRDGAAGVKGDRGETGAVGAPGAPGPPGS------PGPAGP 1081 Query: 3649 QSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPG-PSSQGS 3707 DR A P+ P G ARG + P K + G P +G Sbjct: 1082 TGKQGDRGEAGAQG-----PMGPSGPAG-------ARGIQGPQGPRGDKGEAGEPGERGL 1129 Query: 3708 GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL--------------P 3753 R T G P SG + A+ PA PS P P P P Sbjct: 1130 KGHRGFTGLQGLPGPPGPSGD---QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP 1186 Query: 3754 ARAQAKSCTKGPR-EAGEQGPHGSLGPKEKG 3783 + +S GP G GP G GP G Sbjct: 1187 PGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1217 Score = 45.1 bits (105), Expect = 0.001 Identities = 95/411 (23%), Positives = 125/411 (30%), Gaps = 59/411 (14%) Query: 3504 DPVTHPIRGCELPS-NHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPL 3562 D + ++ C P EC P + P A A G+ P + G PG + Sbjct: 66 DIICEDVKDCLSPEIPFGECCP--ICPTDLATASGQ-----------PGPKGQKGEPGDI 112 Query: 3563 LQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEV 3622 P G P+ A Q G R G++ APG RGR + E Sbjct: 113 KDIVGPKGPPGPQGPAGEQGPRGDRGD---KGEKGAPGPRGR--------------DGEP 155 Query: 3623 SSSHMVSEGGPRG-TFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP- 3680 + GP G G A + D A ++ P+ P G P Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215 Query: 3681 ---------GELARGTENGMK-PATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQ 3730 G E G+ P P+ PGP + G K G + P Q Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG-KPGKAGERGPPGPQGA 274 Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQA-----KSCTKGPREAGEQGPHGSLG-PKEKGE 3784 TP P P A+ +A K + P E G GP G G P E+G Sbjct: 275 RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 334 Query: 3785 SSTKRKKGQ-----VPGPARSES-VGSFGRA--PSAPD-KPPRTPRKQATPSRVLPTKPK 3835 + G PGPA VG G P AP K P P + + Sbjct: 335 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 394 Query: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGA 3886 P + P P + G K G G P P+ GA Sbjct: 395 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 445 Score = 40.0 bits (92), Expect = 0.046 Identities = 56/236 (23%), Positives = 68/236 (28%), Gaps = 30/236 (12%) Query: 3679 APGELAR----GTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA 3734 APG R GT P P PGP G + GG + QL Sbjct: 145 APGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF---AAQMAGGFDEKAGGAQLG--VM 199 Query: 3735 TTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK-------EKGESST 3787 P P P P P P + P E G GP G GP + GE+ Sbjct: 200 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 259 Query: 3788 KRKKGQVPGPARSESVGSFGRAPSAPDKPPRT-------PRKQATPSRVLPTKPKPNSQN 3840 K G+ GP + F P P + +A V P Sbjct: 260 PGKAGE-RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 318 Query: 3841 KPRP------PPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAE 3890 P P P R G + G+ P G P P G GA A+ Sbjct: 319 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 374 Score = 38.9 bits (89), Expect = 0.10 Identities = 101/428 (23%), Positives = 128/428 (29%), Gaps = 68/428 (15%) Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS-EGSL 3477 P F G PGA GQ E ++ PG P P P+G + + +G+ Sbjct: 832 PAGFAGP--PGADGQPGAKGEQGEAGQKGDAGAPG--PQGPSGAPGPQGPTGVTGPKGAR 887 Query: 3478 PALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADG 3537 A P G+P R P ++ G P P + + Sbjct: 888 GAQ-------GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 940 Query: 3538 RGDCALDGALERPENEASPGSPGPLLQQALPLGASLPR-------PGARGQDA-EGKRAP 3589 G+ L G P + PG GP + P L PG RG+ G P Sbjct: 941 AGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 1000 Query: 3590 LVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649 GK+ APGA G + GP G T PAG Sbjct: 1001 SGEPGKQGAPGASG--------------------------DRGPPGPVGPPGLTGPAGEP 1034 Query: 3650 SSSKDRSAASTPSK----ALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQ 3705 A P + +K AVG APG A G PA P K G + Sbjct: 1035 GREGSPGADGPPGRDGAAGVKGDRGETGAVG--APG--APGPPGSPGPAGPTGKQGDRGE 1090 Query: 3706 GS--GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTK 3763 G P G P + A P + R R Q Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE-----RGLKGHRGFTGLQGLPGPP 1145 Query: 3764 GPR----EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA-PSAPDKPPR 3818 GP +G GP G GP S K +PGP G GR+ + P PP Sbjct: 1146 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP--GPRGRSGETGPAGPPG 1203 Query: 3819 TPRKQATP 3826 P P Sbjct: 1204 NPGPPGPP 1211 Score = 37.7 bits (86), Expect = 0.23 Identities = 36/111 (32%), Positives = 43/111 (38%), Gaps = 17/111 (15%) Query: 3187 PGGLEGSSAVAHLLNSITE------PAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAK 3235 P GL G + L E P P GK+ A A+G G P G G A Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA- 1031 Query: 3236 KDSPGERAKPRARSTPSNPDGAA--TPDSASATALADAGSPGPPRTTPSPS 3284 PG P A P DGAA D A+ G+PGPP +P P+ Sbjct: 1032 -GEPGREGSPGADGPPGR-DGAAGVKGDRGETGAVGAPGAPGPP-GSPGPA 1079 Score = 35.4 bits (80), Expect = 1.1 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 6/91 (6%) Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNP-DGAATPDSAS 3264 P K HRG A G G P G +GE+ SPGE P P + T + + Sbjct: 284 PGVKGHRGYPGLDGAKGEAGAP-GVKGES--GSPGENGSPGPMGPRGLPGERGRTGPAGA 340 Query: 3265 ATALADAGSPGP--PRTTPSPSPDPWAGGEP 3293 A A + G PGP P P+ P G P Sbjct: 341 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAP 371 Score = 34.3 bits (77), Expect = 2.5 Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 22/94 (23%) Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSP-------GERAKPRARSTPSNPDGA 3257 +P PK +G+ K P P G +G A + P GE+ P R P Sbjct: 99 QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP--- 155 Query: 3258 ATPDSASATALADAGSPGPPRTTPSPSPDPWAGG 3291 TP G+PGPP P P P GG Sbjct: 156 GTP-----------GNPGPPG-PPGPPGPPGLGG 177 Score = 32.7 bits (73), Expect = 7.3 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%) Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264 +P K +G+ AG+PG P G G +PG + P + P GA P A+ Sbjct: 844 QPGAKGEQGEAGQKGDAGAPG-PQGPSG-----APGPQG-PTGVTGPKGARGAQGPPGAT 896 Query: 3265 ATALADAGSPGPPRTTPSPSP 3285 A AG GPP + +P P Sbjct: 897 GFPGA-AGRVGPPGSNGNPGP 916 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 94.7 bits (234), Expect = 2e-18 Identities = 300/1253 (23%), Positives = 395/1253 (31%), Gaps = 259/1253 (20%) Query: 1693 CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEP 1752 C + +QPGP+ G + +++ PK E P Sbjct: 23 CQGQDVRQPGPK---GQKGEPGDIKDIVGPKGPPGPQGPAGEQG-------------PRG 66 Query: 1753 GTADQPHRGAPAPEAF-GSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQ------- 1804 D+ +GAP P G P P G PP P G + AAQ Sbjct: 67 DRGDKGEKGAPGPRGRDGEPGTPGNP-----GPPGPP-GPPGPPGLGGNFAAQMAGGFDE 120 Query: 1805 ---GHSAGRAGGHLHPT--------AGRPG---FEGNEFAPA--GASSLTAPRGREAWLV 1848 G G G + P AG PG F+GN P G S PRG Sbjct: 121 KAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG--- 177 Query: 1849 PVPSPACVSNTHPSRRSQDPALSPPIRQLQLPG----PGV-----------AKSKDGILG 1893 P P ++ + P PG PGV AK + G G Sbjct: 178 PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG 237 Query: 1894 L--QELTPAAQ-SPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLE 1950 + + +P SP + P GL G G A+G+ G P G G Sbjct: 238 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 297 Query: 1951 ADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEK 2010 G G G+A T +G PE P G SP A G + Sbjct: 298 FPGAPGAKGEAGPTGARG------PEGAQGPRG---EPGTPGSPGPAGASGNPGTDGIPG 348 Query: 2011 CKGSRAAMSLQ-EEAEPTP-SPPSPNRESLALALTAAHSRSGSEGRTPERA--SSPGLNK 2066 KGS A + P P PP P + L G G E+ PG Sbjct: 349 AKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG 408 Query: 2067 PLLATG----DSPAPSVGDLAACAP-SPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQ 2121 P A G + + G+ P P P + G P +D L P A G G Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG-FPGQDGLAGPKGAPGERGPS 467 Query: 2122 LPASP-SCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKE 2180 A P PG P L A G+ V P Sbjct: 468 GLAGPKGANGDPG-------RPGEPGLPGARGLTGRPGDAGPQGKVGP------------ 508 Query: 2181 ALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRA 2240 G+P ED PPG A P P+ + E PG+A Sbjct: 509 ---------SGAPGEDGRPGPPGPQGA------RGQPGVMGFPGPKGANGE-----PGKA 548 Query: 2241 TSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGP-----DPQSRGAPPHTNPDRMP 2295 L G A GL P D G PGP + +GAP + +P Sbjct: 549 GEKGLPG---------APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP 599 Query: 2296 RGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPED---- 2351 P G + G VP E GP GE G+ + Sbjct: 600 ------GPPGPPGEGGKPGD--QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651 Query: 2352 -PGTPET----GRSGATKMPRVTCPSTGL-------GLGRTTAPSSTASDFQSDSPQSHR 2399 PGTP T G SG P P GL G P D P+ Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGP-PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP 710 Query: 2400 NASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGL 2459 P+GP PA NG+ P GP +A R PG Sbjct: 711 GKDGGRGLTGPIGPPG-----------PAGA-NGEKGEVGPPGPAG----SAGARGAPG- 753 Query: 2460 SRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRG--D 2517 R PG P Q + ++ + +K G + P+ + G Sbjct: 754 ----ERGETGPPGPAGFAGPPGADGQPGAK--GEQGEAGQKGDAGAPGPQGPSGAPGPQG 807 Query: 2518 PSHVTQPPPAQGSKEVLRAPGSPHSQ-QLHPPSPTEH--EVDVKTPASKPRPDQAREDEL 2574 P+ VT P A+G++ A G P + ++ PP + P+ K P AR D Sbjct: 808 PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867 Query: 2575 HPKQAEK--REGRRW----RREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVI 2628 P +A + +G + EP D PS +EG + L G+R I+ + Sbjct: 868 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ--GLAGQR----GIVGLPGQ-- 919 Query: 2629 SDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCA 2688 RG R P + + P +G P A G++ P PG+ A E +E Sbjct: 920 ---RGERGFPGLPGPSGEPGK----QGAPGASGDRGPPGPVGPPGLTGPAGEPGRE---- 968 Query: 2689 GETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGA-SARGFWGP-------RETKALGVCK 2740 G GA PPG DGAA + G+ GA A G GP T G Sbjct: 969 GSPGADGPPG--------RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG 1020 Query: 2741 ESGSE-PAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTS-----SCLQGLP 2794 E+G++ P S A +R +G P GP G + P + + LQGLP Sbjct: 1021 EAGAQGPMGPSGPAGARGIQG-------PQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP 1073 Query: 2795 DNPDTQG--GVQGPEGPT-----PDASGSSAKDPPSLFDDEVSFSQLFPPGGR 2840 P G G GP GP+ P G S KD + + PPG R Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG-----PPGPR 1121 Score = 92.8 bits (229), Expect = 6e-18 Identities = 306/1227 (24%), Positives = 381/1227 (31%), Gaps = 267/1227 (21%) Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP--PAAENSFPGANFGVPPAEPEPIPKGSRPG 265 PGP +G +PG + P PA E P + G + P P+G R G Sbjct: 31 PGPKGQKG----EPGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGDKGEKGAPGPRG-RDG 84 Query: 266 --GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGT--- 320 G+P P G P P + G+ FA Q G + E+A G Sbjct: 85 EPGTPGN-------PGPPGPPGPPGPPGLGGN--------FAA-QMAGGFDEKAGGAQLG 128 Query: 321 ---GPAYPL----PTQPAPSPLPC-YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372 GP P+ P PA +P P +QG PG +SG + G +P D Sbjct: 129 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG-VSGPMGPRGPPGPPGKPGDDGE 187 Query: 373 HKSLTKILPERPPSAQDGLG--STRGPPSSLPQRHFPGQ-----AYRASGVDTSPGPPDT 425 K PP Q G T G P R +PG A GV G P Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG- 246 Query: 426 ELAAPGPP-PARLPQLWDPTAA------------PYPTPPGGPLAATRSMFFNGQPSPGQ 472 E +PGP P LP T P P P GP+ F G P + Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG-AK 305 Query: 473 RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--------GSQGALGTA 524 P A P P P G P PAG G GS GA G A Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGS------PGPAGASGNPGTDGIPGAKGSAGAPGIA 359 Query: 525 GKT--PGPREKL-------PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPH-- 573 G PGPR P Q G P + + G P +P G A PQ +P Sbjct: 360 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP---GPAGPQGAPGPA 416 Query: 574 -------------GTPSLPPPRVVGAS-----PSESPLPSPA--------TNTAGSTCSS 607 G + PP GA P + L P + AG ++ Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 476 Query: 608 LSP-MSSSPANPSSEE-SQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEP 665 P P P + + PG GP P P E G P PP QP Sbjct: 477 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP----GPPGPQGARGQPG- 531 Query: 666 AKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFP-------RAPPPYPTHHFS 718 FP P GA G E P G GL+G P A PP P Sbjct: 532 VMGFPGPK---GANGEPGKAGEKGLP------GAPGLRGLPGKDGETGAAGPPGP----- 577 Query: 719 LSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPA 778 A R G A G Q PGPPG P Sbjct: 578 -------------------------AGPAGERGEQG---APGPSGFQGLPGPPGPPGEGG 609 Query: 779 APR---VPADAHA-GLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDM 834 P VP +A A GL+ G+ + G LP T P AS Sbjct: 610 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 669 Query: 835 EDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPE 894 A+ L GM + I D G +GP G+T Sbjct: 670 PPGAQGPP----GLQGMPGERGAAGIAGPK----GDRGDVGEKGPEGAPGKDGGRGLTGP 721 Query: 895 SKAPPPLPAATPDPQTPRPGDRGCP-ARGRP----KTRSLGLAPTEADAPSQGRQQRRGK 949 P P A + PG G ARG P +T G A + G+ +G+ Sbjct: 722 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 781 Query: 950 QLKLFRK-DLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRP----RTQAPGS 1004 Q + +K D + G SG+ G +G+ + + PP P R PGS Sbjct: 782 QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 841 Query: 1005 RADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREY 1064 +P P P + + + +R PP R G G + +K Sbjct: 842 NGNPGPPGPPGPSGKDGPKGARGDSGPP--------GRAGEPGLQGPAGPPGEKG----- 888 Query: 1065 DFASESEEDEQPPPRGPGFRGRRG-------RGEKRKEVELTQGPREDEPQKPRKAARQE 1117 + + + PP G G+RG RGE+ GP + P K Sbjct: 889 EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERG--FPGLPGPSGE----PGKQGAPG 942 Query: 1118 AGGDGAPANPEEPGG-----SRPGPGRSPQARGP----------SRSLETGAAAREGGP- 1161 A GD P P P G PG SP A GP ETGA G P Sbjct: 943 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1002 Query: 1162 ------------KCADRPSVAPKDPL--QVPTNTETSEETRPSLDFPQEAKEPETAEESA 1207 K DR + P+ P + + EA EP E Sbjct: 1003 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP--GERGL 1060 Query: 1208 PDSTEFT--EALRSPPAACAGEMGAS--PGLLIPEQPP----PSRHD--------TGTPK 1251 FT + L PP +G+ GAS G P PP PS D G P Sbjct: 1061 KGHRGFTGLQGLPGPPGP-SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119 Query: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPG 1278 P G T P G PG G PG Sbjct: 1120 PRGRSGETGPAGPPGNPGPPGPPGPPG 1146 Score = 90.1 bits (222), Expect = 4e-17 Identities = 211/804 (26%), Positives = 258/804 (32%), Gaps = 117/804 (14%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGG-QAQAME- 59 PG R R P T P PG P P L N A +AGG Q M+ Sbjct: 77 PGPRGRDGEPGTPGNPGPP----GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 132 Query: 60 ---------------LPEAQPRQARDGELKPPSLRG-QAPSSTPGKRGSPQTP-----PG 98 P Q Q GE P + G P PG G P PG Sbjct: 133 PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG 192 Query: 99 RSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGT 158 ++ + P G A G P + G+ R P LD + E +P G+ Sbjct: 193 KAGERGPPGPQG-ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK-GESGSPGENGS 250 Query: 159 GAPLRP-GLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPR-PPAPG------P 210 P+ P GLP + R P P+ P P APG P Sbjct: 251 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310 Query: 211 PQSRGTSPLQ-----PGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPI-P 259 +RG Q PG+ +GA P P A+ S P P P P Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370 Query: 260 KGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG 319 G + P G Q P + G + P G A G A + + E G Sbjct: 371 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430 Query: 320 TGPAYPLPTQPAPSPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHK 374 GP P + AP + GQ G G SG GA RP L Sbjct: 431 VGPIGPPGERGAPGNRG-FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 489 Query: 375 SLTKILPERP----------PSAQDGLGSTRGPPSSLPQRHFPGQAY--RASGVDTSPGP 422 + + L RP PS G GPP R PG G + PG Sbjct: 490 A--RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 547 Query: 423 PDTELAAPGPPPAR-LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAP 481 E PG P R LP T A P P GP G PS Q L P P Sbjct: 548 AG-EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG-PSGFQGLPGPPGPP 605 Query: 482 ----LPWPQVLPTARPSPHGMEMLSRLPFPA--GGPEWQG--GSQGALGTAGKTPGPREK 533 P Q +P +P + FP G P QG G +G GT G T GP+ Sbjct: 606 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG-TDGPKGA 664 Query: 534 L-PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQP--------QVSPHGTPSLPPPRVV 584 PA G P L GM PG + G+A P + P G P R + Sbjct: 665 SGPAGPPGAQGPPGL---QGM--PGERGAA-GIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718 Query: 585 GASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQET 644 P P P+ A G P S+ A + E GP GP+ F PP + Sbjct: 719 -TGPIGPPGPAGANGEKGEV-GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP 776 Query: 645 GSP-------------FPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691 G+ P P+ P P P+ P GA+G T FP Sbjct: 777 GAKGEQGEAGQKGDAGAPGPQGPSGAPG---PQGPTGVTGPKGARGAQGPPGA---TGFP 830 Query: 692 HEGPEVGRGGLQGFPRAP-PPYPT 714 VG G G P P PP P+ Sbjct: 831 GAAGRVGPPGSNGNPGPPGPPGPS 854 Score = 83.6 bits (205), Expect = 4e-15 Identities = 216/837 (25%), Positives = 264/837 (31%), Gaps = 149/837 (17%) Query: 6 PRGAPPPT-MTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQ 64 PRG P P TG L P+ PG + +G + G A P Sbjct: 367 PRGPPGPQGATGPLGPKGQTGEPG----------IAGFKGEQGPKGEPGPAGPQGAPGPA 416 Query: 65 PRQARDGELKPPSLRGQAPSSTPGKRGSPQTP--PGRSPLQAPSRLAGRAEGSPPQRYIL 122 + + G P G P PG+RG+P PG+ L P +G+P +R Sbjct: 417 GEEGKRGARGEPG--GVGPIGPPGERGAPGNRGFPGQDGLAGP-------KGAPGERGPS 467 Query: 123 GIASSRTKPTLDETPENPQLEAAQ----LPEVDTPQGP--GTGAPLRPGLPRTEAQPAAE 176 G+A + P P L A+ P PQG +GAP G P A Sbjct: 468 GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 527 Query: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236 F P + P PG P RG PG E A+G Sbjct: 528 GQPGVMGFPGPKGA-----NGEPGKAGEKGLPGAPGLRGL----PGKDGETGAAGPPGPA 578 Query: 237 -PAAENSFPGA----NFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGA-STKPFPA 290 PA E GA F P P P +G +PG +GV + P L G + FP Sbjct: 579 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD--QGVPGEAGAPGLVGPRGERGFPG 636 Query: 291 DVA--GHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLN 346 + G GP P P+ A +GPA P P P QG PG G Sbjct: 637 ERGSPGAQGLQGPRGLP-GTPGTDGPKGA--SGPAGP----PGAQGPPGLQGMPGERGAA 689 Query: 347 RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-----------PSAQDGLGSTR 395 + G G P D I P P P G R Sbjct: 690 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 749 Query: 396 GPPSSLPQRHFPGQAYRAS--GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYP---- 449 G P + PG A A G D PG + A A P P+ AP P Sbjct: 750 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809 Query: 450 --TPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP--TARPSPHGMEMLSRLP 505 T P G A G P R+ P S P P P + + P G S P Sbjct: 810 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869 Query: 506 FPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTD-PGAQPLFFG 564 AG P G QG G G+ P + P+ G L G+ PG Sbjct: 870 GRAGEP----GLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPG------- 918 Query: 565 VAQPQVSPHGTPSLPPPR-------VVGASPSESPLPSPA-----TNTAGSTCSSLSPMS 612 Q G P LP P GAS P P P T AG SP + Sbjct: 919 ----QRGERGFPGLPGPSGEPGKQGAPGASGDRGP-PGPVGPPGLTGPAGEPGREGSPGA 973 Query: 613 SSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAF--- 669 P + G G + P P GSP P+ PT Q + +A Sbjct: 974 DGPPGRDGAAG-VKGDRGETGAVGAPGAPGPPGSPGPAG------PTGKQGDRGEAGAQG 1026 Query: 670 ------PFPADGL-GAEGAFQCLEETPFPHE-GPEVGRG--GLQGFPRAPPPYPTHHFSL 719 P A G+ G +G E P E G + RG GLQG P P P Sbjct: 1027 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGP-------- 1078 Query: 720 SSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSP 776 D+ S A R G + KDG PGP G P P Sbjct: 1079 ---------------SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120 Score = 76.6 bits (187), Expect = 4e-13 Identities = 255/1080 (23%), Positives = 320/1080 (29%), Gaps = 221/1080 (20%) Query: 426 ELAAPGPP-----PARLPQLWDPTAAPYPTPPGG---PLAATRSMFFNGQPSPGQRLCLP 477 ++ PGP P + + P P P P G P G P P R P Sbjct: 27 DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86 Query: 478 QSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAV 537 + P P P P P G+ G E GG+Q LG GP P Sbjct: 87 GTPGNPGPPG-PPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ--LGVMQGPMGPMG--PRG 141 Query: 538 RSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA 597 G+P + G +P GV+ P + P G P PP G E+ P A Sbjct: 142 PPGPAGAPGPQGFQGNPGEPGEP---GVSGP-MGPRGPPG--PPGKPG-DDGEAGKPGKA 194 Query: 598 TNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPSAFFHPPTHPQETGSP----FPSPE 652 +P P + + PG G P E+GSP P P Sbjct: 195 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 254 Query: 653 PPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGP-EVGRGGLQGFPRAPPP 711 P LP + PA GA G + P P P VG G GFP AP Sbjct: 255 GPRGLPGE------RGRTGPAGAAGARGN----DGQPGPAGPPGPVGPAGGPGFPGAP-- 302 Query: 712 YPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPP 771 + G AR +G Q G P Sbjct: 303 ------------------------------------GAKGEAGPTGARGPEGAQGPRGEP 326 Query: 772 GLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP-FPLPAS 830 G P P PA A +G+ +G + P +A P FP P Sbjct: 327 GTPGSPG----PAGA-------------SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369 Query: 831 DLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAG 890 + T L G + Q+ P I + EP GP GP + G Sbjct: 370 PPGPQG-------ATGPL-GPKGQTGEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEEG 420 Query: 891 VTPESKAPPPLPAATPDPQTPRPGDRGCPA-------RGRPKTRS-LGLAPTEADAPSQG 942 P + P + PG+RG P +G P R GLA + G Sbjct: 421 KRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480 Query: 943 RQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERP-PPRPRRPRTQA 1001 R G G G G + P G RP PP P+ R Q Sbjct: 481 RPGEPGLP----------GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ- 529 Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061 PG P P+ E + + LP R + G G Sbjct: 530 PGVMGFPGPKGANG-----EPGKAGEKGLPGAPGLRGLPGKDGETGAA---------GPP 575 Query: 1062 REYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQ--------GPREDEPQK 1109 A E E P P G PG G G G K + + GPR + Sbjct: 576 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 635 Query: 1110 PRKAARQEAGGDGAPANPEEPGGSRP----GPGRSPQARGP----SRSLETGAAAREGGP 1161 + + G G P PG P GP P A+GP E GAA GP Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI-AGP 694 Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSP- 1220 K DR V K P P T P E E P A +P Sbjct: 695 K-GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPG 753 Query: 1221 ---------PAACAGEMGA--------------------SPGLLIPEQPPPSRHDTGTPK 1251 PA AG GA +PG P P + TG Sbjct: 754 ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 813 Query: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPG-----GTQAPVSHNSKDPPARQPGEFLAPVANP 1306 P G+ P G++ PG +G PG G P + KD P G+ P Sbjct: 814 PKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-SGPPGRA 872 Query: 1307 SSTACPKPSVLSSKISSFGCD-PAGFNRDPLGVPVAKKGPQPYSSPHSELFL----GPKD 1361 P+ + G D P+G P GPQ + + L G + Sbjct: 873 GEPGLQGPAGPPGEKGEPGDDGPSGAEGPP--------GPQGLAGQRGIVGLPGQRGERG 924 Query: 1362 LAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTA--ETEPGRAASP 1419 G L +P + AP AS G P P PPG EPGR SP Sbjct: 925 FPG--LPGPSGEPGKQGAPGAS-----------GDRGPPGPVGPPGLTGPAGEPGREGSP 971 Score = 72.8 bits (177), Expect = 6e-12 Identities = 255/1066 (23%), Positives = 335/1066 (31%), Gaps = 200/1066 (18%) Query: 466 GQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAG 525 G+P + + P+ P P P P G + + A GP + G G G G Sbjct: 38 GEPGDIKDIVGPKGPPGPQG---PAGEQGPRG-DRGDKGEKGAPGPRGRDGEPGTPGNPG 93 Query: 526 KTPGPREKLPAVRSSQGGSPALFTYNGMTDP--GAQPLFFGVAQPQVSPHGTPSLPPPRV 583 PGP P GG+ A G + GAQ GV Q + P G P PP Sbjct: 94 P-PGPPG--PPGPPGLGGNFAAQMAGGFDEKAGGAQ---LGVMQGPMGPMG-PRGPP--- 143 Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQ- 642 P+ +P P +P P E + GP+GP PP P Sbjct: 144 ---GPAGAPGPQG--------------FQGNPGEPG--EPGVSGPMGPRGPPGPPGKPGD 184 Query: 643 --ETGSPFPSPE--PPHSLPTHYQPEPAKAFPFPADGLGAEG--AFQCLEETPFPHEGPE 696 E G P + E PP P+ A+ FP G +G + L+ P Sbjct: 185 DGEAGKPGKAGERGPPG-------PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG 237 Query: 697 V-GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGL 755 V G G G +P P L G Sbjct: 238 VKGESGSPGENGSPGPMGPR--------------------------GLPGERGRTGPAGA 271 Query: 756 LLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTG 815 AR DG GPPG P P P A AG A G + Sbjct: 272 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK--------GEAGPTGARGPEGAQGPR 323 Query: 816 FLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSS--FIDVFADEEP 873 P +P P AS + T+ + G + + P I + F P Sbjct: 324 GEPGTPGSPGPAGAS----------GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 373 Query: 874 SGPRGP-----SSGHP----LKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924 G GP +G P K + G P+ + P P P P G RG ARG P Sbjct: 374 QGATGPLGPKGQTGEPGIAGFKGEQG--PKGEPGPAGPQGAPGP-AGEEGKRG--ARGEP 428 Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR-PRRN 983 P E AP G + G+ G A G+ G SGL P+ Sbjct: 429 GGVGPIGPPGERGAP--GNRGFPGQD-----------GLAGPKGAPGERGPSGLAGPKGA 475 Query: 984 DGLGERPPPRPRRPRTQ-APGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042 +G P RP P A G P P+ P R PP Sbjct: 476 NG----DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ------- 524 Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGP 1102 GA G+ ++ K E + E+ P PG RG G+ + GP Sbjct: 525 -GARGQPGVMGFPGPKGANGE-----PGKAGEKGLPGAPGLRGLPGK-DGETGAAGPPGP 577 Query: 1103 REDEPQKPRKAARQEAGGDGAPANPEEPG-GSRPG----PGR--SPQARGPSRSL----E 1151 ++ + A +G G P P PG G +PG PG +P GP E Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637 Query: 1152 TGAAAREG--------------GPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEA 1197 G+ +G GPK A P+ P Q P + R + Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP--GAQGPPGLQGMPGERGAAGIAGPK 695 Query: 1198 KEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSL- 1256 + E P+ + R G +G PG P + + G P P+GS Sbjct: 696 GDRGDVGEKGPEGAPGKDGGR----GLTGPIG-PPG---PAGANGEKGEVGPPGPAGSAG 747 Query: 1257 ANTAP--HGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAP-VANPSSTACPK 1313 A AP G + PG G PG P + A Q G+ AP PS P+ Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806 Query: 1314 -PSVLSSKISSFGCD-PAGFNRDP-----LGVPVAKKGPQPYSSPHSELFLGPKDLAGCF 1366 P+ ++ + G P G P +G P + P P P GPK G Sbjct: 807 GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG-- 864 Query: 1367 LEELHPKPSARDAPPASSSCLCQDGE--DAGSLEPQLPRSPPGTAETEPGRA-ASPPTLE 1423 P R P GE + G P PPG R P Sbjct: 865 ----DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 920 Query: 1424 SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPP 1469 FP LP +P G+ A+ D G P PP T P+ P Sbjct: 921 GERGFPGLPGPSGEPGKQGAPGASGDRGPP-GPVGPPGLTGPAGEP 965 Score = 72.0 bits (175), Expect = 1e-11 Identities = 265/1132 (23%), Positives = 348/1132 (30%), Gaps = 234/1132 (20%) Query: 6 PRGAPPPTMTGDLQPRQVASSPGHPSQP----PLEDNTPATRTTKGAR--EAGGQAQAME 59 PRG P P G P+ +PG P +P P+ P K EAG +A E Sbjct: 139 PRGPPGPA--GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 196 Query: 60 LPEAQPRQARD-----------------------GELKPPSLRGQAPSSTPGKRGSP--- 93 P+ AR GE P ++G+ S +PG+ GSP Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE--SGSPGENGSPGPM 254 Query: 94 --QTPPGRSPLQAPSRLAGRAEGSPPQRYILGI-----------------ASSRTKPTLD 134 + PG P+ AG A G+ Q G A PT Sbjct: 255 GPRGLPGERGRTGPAGAAG-ARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 313 Query: 135 ETPENPQLEAAQLPEVDTPQGPG----TGAPLRPGLPRTEAQPAAEELGFHRCF---QEP 187 PE Q E TP PG +G P G+P + A + F + P Sbjct: 314 RGPEGAQ---GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370 Query: 188 PSSFTSTNYTSPSATPRPPA-------------PGPPQSRGTSPLQPGSYPEYQASGADS 234 P +T P P PGP +G PG E GA Sbjct: 371 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA----PGPAGEEGKRGARG 426 Query: 235 WP-------PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287 P P E PG N G P + PKG+ P G++ +G +P Sbjct: 427 EPGGVGPIGPPGERGAPG-NRGFPGQDGLAGPKGAPGERGPSGLAGP---KGANGDPGRP 482 Query: 288 FPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG---- 343 + G G +P A P+ VG A +P P +GQPG Sbjct: 483 GEPGLPGARGLTG-------RPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 535 Query: 344 ----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-----------PSAQ 388 G N +G PGA P D + P P PS Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595 Query: 389 DGLGSTRGPPSSLPQ---RHFPGQAYRASGVDTSPGPPDT-----ELAAPGPP----PAR 436 GL GPP + + PG+A G GP E +PG P Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPGEA----GAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651 Query: 437 LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQR----LCLPQSAPLPWPQVLPTAR 492 LP + P GP A G P G+R + P+ + P Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP--GERGAAGIAGPKGDRGDVGEKGPEGA 709 Query: 493 PSPHGMEMLSRL---PFPAG--GPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547 P G L+ P PAG G + + G G G+AG P E+ + G P Sbjct: 710 PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER------GETGPPGP 763 Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPS-ESPL----PSPATNTAG 602 + G QP G Q + G P P+ +P + P P A G Sbjct: 764 AGFAGPPGADGQPGAKG-EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 822 Query: 603 STCSSLSPMSSSPANP--SSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEP---PHSL 657 ++ P ++ P S+ PGP GPS P ++G P + EP + Sbjct: 823 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 882 Query: 658 PTHYQPEPAKAFPFPADG----------LGAEGAFQCLEETPFPHEGPEVGRGGLQGFPR 707 P + EP P A+G G G E FP G G QG P Sbjct: 883 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 942 Query: 708 AP----PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDG 763 A PP P L+ + + R S A R G + G Sbjct: 943 ASGDRGPPGPVGPPGLTGPA----------GEPGREGSPGADGPPGRD--GAAGVKGDRG 990 Query: 764 HQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAAT 823 + G PG P PP +P PA GD G P+ PS A Sbjct: 991 ETGAVGAPGAPGPPGSPG-PAGPTG----------KQGDRGEAGAQGPMG----PSGPAG 1035 Query: 824 PFPLPASDLDMEDDAKLDSLITEALNGME-----YQSDNPEIDSSFIDVFADEEPSGPRG 878 + D + L G P S PSGPRG Sbjct: 1036 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1095 Query: 879 PSSGHPLKSKAGVT----------PESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRS 928 P K G P ++ PA P P PG G P G + Sbjct: 1096 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP-PGPPGPPGPGIDMSAF 1154 Query: 929 LGLAPTE----------ADAPSQGRQQRRGK---QLKLFRKDLDSGGAAEGS 967 GL P E AD + G +Q + LK ++S + EGS Sbjct: 1155 AGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGS 1206 Score = 63.9 bits (154), Expect = 3e-09 Identities = 123/507 (24%), Positives = 162/507 (31%), Gaps = 66/507 (13%) Query: 3414 RGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473 +G P F+G+ PG PG EG P + +PG A PG PRG Sbjct: 587 QGAPGPSGFQGL--PGPPGPPG---EGGKPGDQ---GVPGEAGAPG--LVGPRGERGFPG 636 Query: 3474 EGSLPALLHLCSEVAPSTTKGW--PETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFP 3531 E P L T G P+ P P G + P Q P + Sbjct: 637 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP-----GAQGPPGLQGMPGERGAAGI 691 Query: 3532 AALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAE-GKRAP 3589 A RGD G P + G GP+ P P GA G+ E G P Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI---------GPPGPAGANGEKGEVGPPGP 742 Query: 3590 LVFSGKRRAPGARGRCA----------PDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHK 3639 +G R APG RG P + ++ E GP+G Sbjct: 743 AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802 Query: 3640 GSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAK 3699 P G + K A P A FP A G + P + G P P K Sbjct: 803 PGPQGPTGV-TGPKGARGAQGPPGATGFP----GAAGRVGPPG-SNGNPGPPGPPGPSGK 856 Query: 3700 PGPSSQGSGSPRPGTKTGGGSQ-PQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQA 3758 GP S PG G Q P G+ P+ P P P+ L A Sbjct: 857 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP---PGPQGL---AGQ 910 Query: 3759 KSCTKGPREAGEQGPHGSLGPKEK-------GESSTKRKKGQVPGPARSESVGSFGR--A 3809 + P + GE+G G GP + G S + G V P + G GR + Sbjct: 911 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970 Query: 3810 PSAPDKPPRTPRKQATPSR----VLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGK 3865 P A P R R + P P P ++ + G + +G Sbjct: 971 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030 Query: 3866 AFPQGRPLLRPPK--RGTAVHGAEPAE 3890 + P G ++ P+ RG EP E Sbjct: 1031 SGPAGARGIQGPQGPRGDKGEAGEPGE 1057 Score = 61.2 bits (147), Expect = 2e-08 Identities = 170/653 (26%), Positives = 209/653 (32%), Gaps = 138/653 (21%) Query: 2 PGER--PRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-----NTPATRTTKGAREAGGQ 54 PG++ P A P + G R G P L+ TP T KGA G Sbjct: 611 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 670 Query: 55 AQAMELPEAQPRQARDGELK---PPSLRG----QAPSSTPGKRGS-----PQTPPGRSPL 102 A P Q G P RG + P PGK G P PPG Sbjct: 671 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG---- 726 Query: 103 QAPSRLAG-RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAP 161 P+ G + E PP G A +R P + E P G P Sbjct: 727 --PAGANGEKGEVGPPGP--AGSAGARGAP-------------GERGETGPPGPAGFAGP 769 Query: 162 LRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAP----GPPQSRGT 216 P + QP A+ E G Q+ + PS P P P GP +RG Sbjct: 770 -----PGADGQPGAKGEQG--EAGQKGDAGAPGPQ--GPSGAPGPQGPTGVTGPKGARGA 820 Query: 217 SPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPI----PKGSRPGGSPRGVS 272 PG+ A+G P N PG PP P P PKG+R P G + Sbjct: 821 QG-PPGATGFPGAAGRVG--PPGSNGNPG-----PPGPPGPSGKDGPKGARGDSGPPGRA 872 Query: 273 FQFPFPALHGASTKPF----PADVAGHAFTNGPLVFAFHQPQGAWPEEAV----GTGPAY 324 + P L G + P P D G + GP PQG + + G Sbjct: 873 GE---PGLQGPAGPPGEKGEPGD-DGPSGAEGP-----PGPQGLAGQRGIVGLPGQRGER 923 Query: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384 P P PS P QG PG G + PG A P + + + P Sbjct: 924 GFPGLPGPSGEPGKQGAPGASGDRGP-PGPVGPPGLTGPAGEPGREGSPGA------DGP 976 Query: 385 PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP-PARLPQLWDP 443 P +DG +G PG +PGPP +PGP P Sbjct: 977 PG-RDGAAGVKGDRGETGAVGAPG----------APGPP----GSPGPAGPTGKQGDRGE 1021 Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503 A P P GP A G P A P + L R G L Sbjct: 1022 AGAQGPMGPSGPAGA------RGIQGPQGPRGDKGEAGEPGERGLKGHR----GFTGLQG 1071 Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPR-EKLPAVRSSQGGSPALFTYNGMTDPGAQPLF 562 LP GP G QGA G AG + GPR P S + G+ NG+ P P Sbjct: 1072 LP----GPPGPSGDQGASGPAGPS-GPRGPPGPVGPSGKDGA------NGIPGPIGPPGP 1120 Query: 563 FGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSP 615 G + P G P P P P P P + S + L P P Sbjct: 1121 RG-RSGETGPAGPPGNPGP------PGPPGPPGPGIDM--SAFAGLGPREKGP 1164 Score = 55.1 bits (131), Expect = 1e-06 Identities = 117/479 (24%), Positives = 144/479 (30%), Gaps = 72/479 (15%) Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488 G G + E P R R PG+ PG PP P L + E A Sbjct: 63 GPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKA 122 Query: 3489 PSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECP-----PPSLSPF-PAALADGRGDC 3541 G + P+ P P G P Q P P P P G Sbjct: 123 GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP 182 Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR-PGARG----QDAEGKRAPLVFSGKR 3596 DG +P G PGP + P LP G RG A+G+ G+ Sbjct: 183 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242 Query: 3597 RAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGC-------- 3648 +PG G P GPRG + T PAG Sbjct: 243 GSPGENGSPGP-----------------------MGPRGLPGERGRTGPAGAAGARGNDG 279 Query: 3649 QSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSG 3708 Q P+ FP P A G P ARG E P PG Sbjct: 280 QPGPAGPPGPVGPAGGPGFPGAP-GAKGEAGPTG-ARGPEGAQGPRGEPGTPGSPGPAGA 337 Query: 3709 SPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREA 3768 S PGT G++ + + A P P P P P+ K T P A Sbjct: 338 SGNPGTDGIPGAKGSAGAPGI----AGAPGFPG-PRGPPGPQGATGPLGPKGQTGEPGIA 392 Query: 3769 ---GEQGPHGSLGPK----EKGESSTKRKKGQVPGPARSESVGSFGR--APSAPDKP--- 3816 GEQGP G GP G + + K+G P +G G AP P Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452 Query: 3817 ----PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGR 3871 P+ + PS + K +P P PG R G A PQG+ Sbjct: 453 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP------GLPGARGLTGRPGDAGPQGK 505 Score = 54.3 bits (129), Expect = 2e-06 Identities = 116/469 (24%), Positives = 154/469 (32%), Gaps = 56/469 (11%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG G LP +R R G+A G D P P V Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPP--------------GPV 290 Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA- 3546 P+ G+P + RG E + P SP PA + G + GA Sbjct: 291 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 350 Query: 3547 --LERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFS-GKRRAPGARG 3603 P +PG PGP P GA+ P G +GQ E A G + PG G Sbjct: 351 GSAGAPGIAGAPGFPGPRGPPG-PQGATGPL-GPKGQTGEPGIAGFKGEQGPKGEPGPAG 408 Query: 3604 -RCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP-----AGCQSSSKDR-- 3655 + AP E+ E + G RG G+ P AG + + +R Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA--PGNRGFPGQDGLAGPKGAPGERGP 466 Query: 3656 SAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTK 3715 S + P A P P + PG ARG A P+ K GPS RPG Sbjct: 467 SGLAGPKGANGDPGRPGEPG---LPG--ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP- 520 Query: 3716 TGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP---REAGEQG 3772 PQ A GQ P FP A P +A K P G+ G Sbjct: 521 ----PGPQGARGQ--------PGVMGFPGPKGANGE-PGKAGEKGLPGAPGLRGLPGKDG 567 Query: 3773 PHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP--PRTPRKQATPSRVL 3830 G+ GP + +R + PGP+ + + P KP P + P V Sbjct: 568 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627 Query: 3831 PTKPK--PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPP 3877 P + P + P + + PG G + P G P + P Sbjct: 628 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 676 Score = 46.2 bits (108), Expect = 6e-04 Identities = 107/391 (27%), Positives = 128/391 (32%), Gaps = 65/391 (16%) Query: 3415 GGRQPFAFRGVRRP-GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473 G P GV P GA G + P RV PGS PG PP P Sbjct: 801 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP----GPSGK 856 Query: 3474 EGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA 3533 +G A + P G P L+ P P + + E PP P Sbjct: 857 DGPKGAR----GDSGPPGRAGEPG-LQGPAGPPGEKGEPGDDGPSGAEGPPG-----PQG 906 Query: 3534 LADGRGDCALDGALERPENEASPGSPGPLLQ---QALPLGASLPR--PGARGQDAEGKRA 3588 LA RG L G +R E PG PGP + Q P GAS R PG G G Sbjct: 907 LAGQRGIVGLPG--QRGER-GFPGLPGPSGEPGKQGAP-GASGDRGPPGPVGPP--GLTG 960 Query: 3589 PLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGC 3648 P G+ +PGA G P + E + GP G+ PAG Sbjct: 961 PAGEPGREGSPGADG--PPGRDGAAGVKGDRGETGAVGAPGAPGPPGS------PGPAGP 1012 Query: 3649 QSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPG-PSSQGS 3707 DR A P+ P G ARG + P K + G P +G Sbjct: 1013 TGKQGDRGEAGAQG-----PMGPSGPAG-------ARGIQGPQGPRGDKGEAGEPGERGL 1060 Query: 3708 GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL--------------P 3753 R T G P SG + A+ PA PS P P P P Sbjct: 1061 KGHRGFTGLQGLPGPPGPSGD---QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP 1117 Query: 3754 ARAQAKSCTKGPR-EAGEQGPHGSLGPKEKG 3783 + +S GP G GP G GP G Sbjct: 1118 PGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1148 Score = 44.7 bits (104), Expect = 0.002 Identities = 85/367 (23%), Positives = 112/367 (30%), Gaps = 45/367 (12%) Query: 3547 LERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCA 3606 + +P + G PG + P G P+ A Q G R G++ APG RGR Sbjct: 28 VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD---KGEKGAPGPRGR-- 82 Query: 3607 PDHFQEDHLLQKEKEVSSSHMVSEGGPRG-TFHKGSATKPAGCQSSSKDRSAASTPSKAL 3665 + E + GP G G A + D A + Sbjct: 83 ------------DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVM 130 Query: 3666 KFPVHPRKAVGSLAP----------GELARGTENGMK-PATPKAKPGPSSQGSGSPRPGT 3714 + P+ P G P G E G+ P P+ PGP + G Sbjct: 131 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG- 189 Query: 3715 KTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQA-----KSCTKGPREAG 3769 K G + P Q TP P P A+ +A K + P E G Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249 Query: 3770 EQGPHGSLG-PKEKGESSTKRKKGQ-----VPGPARSES-VGSFGRA--PSAPD-KPPRT 3819 GP G G P E+G + G PGPA VG G P AP K Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 309 Query: 3820 PRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKR 3879 P P + +P + P P + G K G G P P+ Sbjct: 310 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369 Query: 3880 GTAVHGA 3886 GA Sbjct: 370 PPGPQGA 376 Score = 40.0 bits (92), Expect = 0.046 Identities = 56/236 (23%), Positives = 68/236 (28%), Gaps = 30/236 (12%) Query: 3679 APGELAR----GTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA 3734 APG R GT P P PGP G + GG + QL Sbjct: 76 APGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF---AAQMAGGFDEKAGGAQLG--VM 130 Query: 3735 TTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK-------EKGESST 3787 P P P P P P + P E G GP G GP + GE+ Sbjct: 131 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 190 Query: 3788 KRKKGQVPGPARSESVGSFGRAPSAPDKPPRT-------PRKQATPSRVLPTKPKPNSQN 3840 K G+ GP + F P P + +A V P Sbjct: 191 PGKAGE-RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249 Query: 3841 KPRP------PPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAE 3890 P P P R G + G+ P G P P G GA A+ Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 305 Score = 38.9 bits (89), Expect = 0.10 Identities = 101/428 (23%), Positives = 128/428 (29%), Gaps = 68/428 (15%) Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS-EGSL 3477 P F G PGA GQ E ++ PG P P P+G + + +G+ Sbjct: 763 PAGFAGP--PGADGQPGAKGEQGEAGQKGDAGAPG--PQGPSGAPGPQGPTGVTGPKGAR 818 Query: 3478 PALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADG 3537 A P G+P R P ++ G P P + + Sbjct: 819 GAQ-------GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 871 Query: 3538 RGDCALDGALERPENEASPGSPGPLLQQALPLGASLPR-------PGARGQDA-EGKRAP 3589 G+ L G P + PG GP + P L PG RG+ G P Sbjct: 872 AGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 931 Query: 3590 LVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649 GK+ APGA G + GP G T PAG Sbjct: 932 SGEPGKQGAPGASG--------------------------DRGPPGPVGPPGLTGPAGEP 965 Query: 3650 SSSKDRSAASTPSK----ALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQ 3705 A P + +K AVG APG A G PA P K G + Sbjct: 966 GREGSPGADGPPGRDGAAGVKGDRGETGAVG--APG--APGPPGSPGPAGPTGKQGDRGE 1021 Query: 3706 GS--GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTK 3763 G P G P + A P + R R Q Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE-----RGLKGHRGFTGLQGLPGPP 1076 Query: 3764 GPR----EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA-PSAPDKPPR 3818 GP +G GP G GP S K +PGP G GR+ + P PP Sbjct: 1077 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP--GPRGRSGETGPAGPPG 1134 Query: 3819 TPRKQATP 3826 P P Sbjct: 1135 NPGPPGPP 1142 Score = 37.7 bits (86), Expect = 0.23 Identities = 36/111 (32%), Positives = 43/111 (38%), Gaps = 17/111 (15%) Query: 3187 PGGLEGSSAVAHLLNSITE------PAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAK 3235 P GL G + L E P P GK+ A A+G G P G G A Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA- 962 Query: 3236 KDSPGERAKPRARSTPSNPDGAA--TPDSASATALADAGSPGPPRTTPSPS 3284 PG P A P DGAA D A+ G+PGPP +P P+ Sbjct: 963 -GEPGREGSPGADGPPGR-DGAAGVKGDRGETGAVGAPGAPGPP-GSPGPA 1010 Score = 35.4 bits (80), Expect = 1.1 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 6/91 (6%) Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNP-DGAATPDSAS 3264 P K HRG A G G P G +GE+ SPGE P P + T + + Sbjct: 215 PGVKGHRGYPGLDGAKGEAGAP-GVKGES--GSPGENGSPGPMGPRGLPGERGRTGPAGA 271 Query: 3265 ATALADAGSPGP--PRTTPSPSPDPWAGGEP 3293 A A + G PGP P P+ P G P Sbjct: 272 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAP 302 Score = 35.0 bits (79), Expect = 1.5 Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 22/96 (22%) Query: 3203 ITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSP-------GERAKPRARSTPSNPD 3255 + +P PK +G+ K P P G +G A + P GE+ P R P Sbjct: 28 VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP- 86 Query: 3256 GAATPDSASATALADAGSPGPPRTTPSPSPDPWAGG 3291 TP G+PGPP P P P GG Sbjct: 87 --GTP-----------GNPGPPG-PPGPPGPPGLGG 108 Score = 32.7 bits (73), Expect = 7.3 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%) Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264 +P K +G+ AG+PG P G G +PG + P + P GA P A+ Sbjct: 775 QPGAKGEQGEAGQKGDAGAPG-PQGPSG-----APGPQG-PTGVTGPKGARGAQGPPGAT 827 Query: 3265 ATALADAGSPGPPRTTPSPSP 3285 A AG GPP + +P P Sbjct: 828 GFPGA-AGRVGPPGSNGNPGP 847 >gi|95147555 microtubule-associated protein 1A [Homo sapiens] Length = 2803 Score = 94.4 bits (233), Expect = 2e-18 Identities = 252/1073 (23%), Positives = 341/1073 (31%), Gaps = 240/1073 (22%) Query: 4 ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEA 63 E P G PP + ++ SP PP +P + A GQ + P+ Sbjct: 1775 ESPVGLPPE------EEDKLTRSPFEIISPPA---SPPEMVGQRVPSAPGQESPIPDPKL 1825 Query: 64 QPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILG 123 P E PS P P R P P SP P A E P + G Sbjct: 1826 MPHMKN--EPTTPSWLADIPPWVPKDRPLPPAP--LSPAPGPPTPA--PESHTPAPFSWG 1879 Query: 124 IASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRC 183 A D Q AA+L P P G R E + AE Sbjct: 1880 TAE------YDSVVAAVQEGAAELE--GGPYSP-LGKDYRKAEGEREEEGRAEAPDKSSH 1930 Query: 184 FQEPPSSFTSTNYTSPSATP---RPPAPGPPQSR-------------GTSPLQPGSYPEY 227 + P + S T P T R P P P + G P P P Sbjct: 1931 SSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPL 1990 Query: 228 QASGADSWPP--AAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGAST 285 A+G WPP + + + G N PI S +P F + AL G + Sbjct: 1991 GAAG--DWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPT-----FSYAALAGPTV 2043 Query: 286 KPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAV-GTGPAYPL--------PTQPAPSPLP 336 P P GP + P P + GP+ PL P + +PSP Sbjct: 2044 PPRPEP--------GPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKE 2095 Query: 337 CYQGQPGGLNRHSDLS-GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTR 395 + S+L GA P +P P + + PE L S Sbjct: 2096 SGRSHWDDSTSDSELEKGAREQPEKEAQSPSP-PHPIPMGSPTLWPETEAHVSPPLDSHL 2154 Query: 396 GPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT----- 450 GP + P FP A+ S + P P +LP +P +AP + Sbjct: 2155 GP--ARPSLDFPASAFGFSSLQ--------------PAPPQLPSPAEPRSAPCGSLAFSG 2198 Query: 451 ------PPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRL 504 PG P + +P LPQ LP+ PS G +LS L Sbjct: 2199 DRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQ---------LPS--PSSPGAPLLSNL 2247 Query: 505 PFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG 564 P PA +G S A + R P++ +++ S G DPG +P Sbjct: 2248 PRPASPALSEGSSSEATTPVISSVAERFS-PSLEAAEQES-------GELDPGMEP---- 2295 Query: 565 VAQPQVSPHGTPSLPPPRVVGASPSESPLP-SPATNTAGSTCSSLSPMSSSPANPSSEES 623 + H L P + A P+ L +PA + G + P + ++E+ Sbjct: 2296 ------AAHSLWDLTP--LSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEK- 2346 Query: 624 QLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQ 683 PS F P G SP PP P + E A A P G EGA + Sbjct: 2347 -------PSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAER 2399 Query: 684 CLE-ETPFPHEGPEVGRGGLQGFPRAPPPY-----------PTHHFSLSSASLDQLDVLL 731 +T E P GG G P + P P H S S L+ L Sbjct: 2400 SSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSF--LNPPL 2457 Query: 732 TCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLL 791 DR+ S+ L R R + G PG G P P P A Sbjct: 2458 PPSIDDRDLSTEEVRLVGRG------GRRRVG---GPGTTGGPCPVTDETPPTSASD--- 2505 Query: 792 SHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGM 851 +G +Q++ D P T PS+ A +A LDS Sbjct: 2506 --------SGSSQSDS-DVPPETEECPSITA--------------EAALDS--------- 2533 Query: 852 EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911 + D F+ V SG P GH PPPLP P P P Sbjct: 2534 -------DEDGDFLPVDKAGGVSGTHHPRPGHD-------------PPPLPQPDPRPSPP 2573 Query: 912 RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971 RP + +A E + GR +R ++ K+ + G Sbjct: 2574 RP--------------DVCMADPEGLSSESGRVERLREKEKVQGR----------VGRRA 2609 Query: 972 GGRASGLRP-RRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETR 1023 G+A P RR D G+R P + P +A SRA P PR + P E + Sbjct: 2610 PGKAKPASPARRLDLRGKRSPTPGKGPADRA--SRAPPRPRSTTSQVTPAEEK 2660 Score = 59.7 bits (143), Expect = 6e-08 Identities = 215/937 (22%), Positives = 301/937 (32%), Gaps = 160/937 (17%) Query: 1457 ADPPQ---KTVPSDP------PYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVV 1507 A PP+ + VPS P P P + + P PS D+ + PP + Sbjct: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPA-PLS 1858 Query: 1508 PGAAPSLPGKGSGCSVALMSHLSEDE---LEIQKLVTELE-------------SQLQRSK 1551 P P P S +E + +Q+ ELE ++ +R + Sbjct: 1859 PAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREE 1918 Query: 1552 DTRG-APRELAEAESVGRVELGTGTEPPSQRRTCQ---ATVPHEDTFSAADLTRVGESTA 1607 + R AP + + + V T P Q Q P E +F AD+ T Sbjct: 1919 EGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLT- 1977 Query: 1608 HREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQ 1667 G A T E G G WP S A A+++L S P SP+ Sbjct: 1978 ---GLGPACPTREPPLGA-AGDWPPCLSTKEAAAGRNTSAEKELSS--PISPKSLQSD-T 2030 Query: 1668 PVQKAGASKTGLCQAEGDSRPPQDVCLPEP---------SKQPGPQLDAGSLAKCSPDQE 1718 P A + P + L P SK P P L+ G++ CSPD+ Sbjct: 2031 PTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLN-GNILSCSPDRR 2089 Query: 1719 LSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGA-----PAPEAFGSPAV 1773 PK + +S L E G +QP + A P P GSP + Sbjct: 2090 SPSPKESGRSHWDDSTSDSEL-----------EKGAREQPEKEAQSPSPPHPIPMGSPTL 2138 Query: 1774 ------HLAPDL-AFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEG 1826 H++P L + G P LD F AS A G S+ + P+ P Sbjct: 2139 WPETEAHVSPPLDSHLGPARPSLD----FPAS----AFGFSSLQPAPPQLPSPAEP---- 2186 Query: 1827 NEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQL--------- 1877 AP G SL R L P P P + ++ P+L + QL Sbjct: 2187 -RSAPCG--SLAFSGDRALALAPGP-PTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAP 2242 Query: 1878 ---QLPGPGVAKSKDGILGLQELTPAAQS-PPRVNPSGLEGGTVEGGKVACGPAQGSPGG 1933 LP P +G + TP S R +PS LE E G++ G + Sbjct: 2243 LLSNLPRPASPALSEG-SSSEATTPVISSVAERFSPS-LEAAEQESGELDPGMEPAAHSL 2300 Query: 1934 VQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNA- 1992 +T L L L L A G L S T+ + Sbjct: 2301 WDLTPLSPAPPASLDL-------ALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVP 2353 Query: 1993 SPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPS------PPSPNRESLALALTAAH 2046 S A GPTE + G A + EEA P+ P R S L + Sbjct: 2354 SEDCAANGPTETS---PNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPE 2410 Query: 2047 S----RSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPL 2102 GS G P ++SP + P P G+L+ +P +P S+ Sbjct: 2411 QPVCPAGGSGG--PPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPP----LPPSIDD- 2463 Query: 2103 PREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAE 2162 D T R G G + P P P + P +D + +D+ Sbjct: 2464 --RDLSTEEVRLVGRGGRRRVGGPGTTGGPCP-----VTDETPPTSASDSGSSQSDSDVP 2516 Query: 2163 DSPVAPPSLTTS------------PCDPKEALAGCLLQGEGS-----PLEDPSSWPPGSV 2205 PS+T P D ++G G P DP PP Sbjct: 2517 PETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPP--- 2573 Query: 2206 SAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPT 2265 C + + R+ KEK+ GR +P A SP+ + G S PT Sbjct: 2574 RPDVCMADPEGLSSESGRVERLREKEKVQGRVGR-RAPGKAKPASPARRLDLRGKRS-PT 2631 Query: 2266 GDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302 + A R P P+ R P GHS S Sbjct: 2632 PGKGPADRASRAP-PRPRSTTSQVTPAEEKDGHSPMS 2667 Score = 54.7 bits (130), Expect = 2e-06 Identities = 115/460 (25%), Positives = 170/460 (36%), Gaps = 79/460 (17%) Query: 3434 KARALEGTLPSKRRRVAMPG-SAPGPGEDRPPPRGSSPILSEGS-----LPALLHLCSEV 3487 KA +L+ +LP +P S+PG PR +SP LSEGS P + + Sbjct: 2222 KAPSLDSSLPQ------LPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERF 2275 Query: 3488 APSTTKGWPET--LERPVDPVTHPIRGCELPSNHQECPPPS----LSPFPAALADGRGDC 3541 +PS E+ L+ ++P H + S PP S L+P P+ D GD Sbjct: 2276 SPSLEAAEQESGELDPGMEPAAHSLWDLTPLS---PAPPASLDLALAPAPSLPGD-MGDG 2331 Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR------PGARGQDAEGKRAPLVFSGK 3595 L LE +EA+ P P + A+ P PG AE + A + + Sbjct: 2332 ILPCHLEC--SEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWE 2389 Query: 3596 RRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR 3655 R GA A + D LL E+ V + GGP + P GC + + Sbjct: 2390 R---GAWPEGAERSSRPDTLLSPEQPVCPAG--GSGGPPSSASPEVEAGPQGCATEPRPH 2444 Query: 3656 SAASTPSKALKFPVHPRKAVGSLAPGEL------------ARGTENGMKPATPKAKPGPS 3703 +PS L P+ P L+ E+ GT G P T + P S Sbjct: 2445 RGELSPS-FLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPP-TS 2502 Query: 3704 SQGSGSPRPGTKTGGGSQPQP---ASGQLQSE--------------TATTPAKPSF-PSR 3745 + SGS + + ++ P A L S+ + T +P P Sbjct: 2503 ASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPP 2562 Query: 3746 SPAPERLPARAQAKSCTKGPRE-AGEQGPHGSLGPKEKGESSTKRK---KGQVPGPARSE 3801 P P+ P+ + C P + E G L KEK + R+ K + PAR Sbjct: 2563 LPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRL 2622 Query: 3802 SVGSFGRAPSAPDKPP------RTPRKQATPSRVLPTKPK 3835 + G+ P K P PR ++T S+V P + K Sbjct: 2623 DLR--GKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEK 2660 Score = 47.4 bits (111), Expect = 3e-04 Identities = 178/777 (22%), Positives = 249/777 (32%), Gaps = 146/777 (18%) Query: 3166 LREHAVRFARRGQARRSLGDLPG-GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSP 3224 LREHA R + P GLE +A + + P + + RS + P Sbjct: 1742 LREHATRSPWASDFKDFQESSPQKGLEVERWLAE--SPVGLPPEEEDKLTRSPFEIISPP 1799 Query: 3225 GDPWGQEGEAKKDSPGERAK-------PRARSTPSNPDGAA-----TPDSASATALADAG 3272 P G+ +PG+ + P ++ P+ P A P + Sbjct: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSP 1859 Query: 3273 SPGPPRTTP---SPSPDPWAGGE------------PLLQATPVHEACKD----------- 3306 +PGPP P +P+P W E L+ P KD Sbjct: 1860 APGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEE 1919 Query: 3307 -----PSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGE---------- 3351 P + H + P+ K A P++ R P YP+ Sbjct: 1920 GRAEAPDKSSH--SSKVPEASKSH---ATTEPEQTEPEQREPTPYPDERSFQYADIYEQM 1974 Query: 3352 LLAHLGGAHGLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNK 3411 +L LG A E P C + A + N T A+KE K Sbjct: 1975 MLTGLGPACPTREPPLGAAGDWPPC---------LSTKEAAAGRN-TSAEKELSSPISPK 2024 Query: 3412 HLRGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRP--PPRGSS 3469 L+ F++ + P P + PG + P P PPR + Sbjct: 2025 SLQSDTPTFSYAALAGPTVPPRPE----------------PGPSMEPSLTPPAVPPR--A 2066 Query: 3470 PILSEGSLPALLHLCSEVAPSTTKGWPETLERP-VDPVTHPIR----GCELPSNHQECP- 3523 PILS+G P L +P P+ R D T E P + P Sbjct: 2067 PILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPS 2126 Query: 3524 PPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA 3583 PP P + + + L+ A P P A + P P A Sbjct: 2127 PPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFP--ASAFGFSSLQPAPPQLPSPA 2184 Query: 3584 EGKRAP---LVFSGKRR---APGARGRCAPDHFQEDHLLQKEKEVSSS--HMVSEGGPRG 3635 E + AP L FSG R APG R D + E + K + SS + S P G Sbjct: 2185 EPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLE---VTKAPSLDSSLPQLPSPSSP-G 2240 Query: 3636 TFHKGSATKPAGCQSSSKDRSAASTP---SKALKFPVHPRKAVGSLAPGELARGTE---- 3688 + +PA S S A+TP S A +F P GEL G E Sbjct: 2241 APLLSNLPRPASPALSEGSSSEATTPVISSVAERF--SPSLEAAEQESGELDPGMEPAAH 2298 Query: 3689 -----NGMKPATPKA-----KPGPS---SQGSGSPRPGTKTGGGSQPQPASGQLQSE--T 3733 + PA P + P PS G G + + +P+ Q+ SE Sbjct: 2299 SLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCA 2358 Query: 3734 ATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQ 3793 A P + S PAP + +A +C R A +G S P T Q Sbjct: 2359 ANGPTETSPNPPGPAPAK-AENEEAAACPAWERGAWPEGAERSSRP------DTLLSPEQ 2411 Query: 3794 VPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQR 3850 PA GS G SA + P+ AT R + P+ N P PP + R Sbjct: 2412 PVCPAG----GSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDR 2464 Score = 43.1 bits (100), Expect = 0.005 Identities = 178/789 (22%), Positives = 246/789 (31%), Gaps = 176/789 (22%) Query: 2026 PTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAAC 2085 PT PP L+ + +G + SSP K L + D+P S LA Sbjct: 1984 PTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQS--DTPTFSYAALAG- 2040 Query: 2086 APSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWA 2145 PT + P P P PS + + P PP +L+CSP Sbjct: 2041 ---PT--------VPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRR 2089 Query: 2146 PLEEADGVQATTDTGAEDSPV------APPSLTTSPCDPKEALAGCLLQGEGSPLEDPSS 2199 + ++ D DS + P SP P P+ P+ Sbjct: 2090 SPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPI-----------PMGSPTL 2138 Query: 2200 WP--PGSVSAVTCTHSGDTPKDSTLRIPEDS-RKEKLWESPGRATSP------------- 2243 WP VS +H G P +L P + L +P + SP Sbjct: 2139 WPETEAHVSPPLDSHLG--PARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAF 2196 Query: 2244 --PLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPG-PDPQSRGAPPHTNPDRMPRGHSS 2300 A A++P R LP P P S GAP +N +PR Sbjct: 2197 SGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSN---LPR---- 2249 Query: 2301 YSPSNTARLGHREGQAVTAVPTE-----PPTLQGAGPDSPACLEGEMGTSSKEPEDPGTP 2355 P++ A +A T V + P+L+ A +S GE+ DPG Sbjct: 2250 --PASPALSEGSSSEATTPVISSVAERFSPSLEAAEQES-----GEL--------DPGME 2294 Query: 2356 ETGRSGATKMPRVTCPSTGLGLGRTTAPS---------------------STASDFQSDS 2394 S P P L L APS S FQ S Sbjct: 2295 PAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPS 2354 Query: 2395 PQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQW-----KGQAPHGPVTCE-- 2447 N +T P GP K + PA E G W + P ++ E Sbjct: 2355 EDCAANGPTETSPNPP-GPAPAKAENEEAAACPA-WERGAWPEGAERSSRPDTLLSPEQP 2412 Query: 2448 VCAASFRSGPGLSRHK---------ARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPP 2498 VC A GP S A + RPH G E SP+ L PL P Sbjct: 2413 VCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRG---ELSPSFL--NPPLPPSIDDRDLS 2467 Query: 2499 RKKSHRV--SGKERPN--HSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHE 2554 ++ V G+ R + G P VT P + + GS S PP TE Sbjct: 2468 TEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASD----SGSSQSDSDVPPE-TEEC 2522 Query: 2555 VDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSP------------------ 2596 + A+ D + + P P D P Sbjct: 2523 PSITAEAAL---DSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCM 2579 Query: 2597 SHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGG 2656 + EG S++ R RLRE+ + GR R +P A ASP+ L + G Sbjct: 2580 ADPEGLSSESG---RVERLREKEKV--------QGRVGRRAPGKAK-PASPARRLDLRG- 2626 Query: 2657 PEADGEQPPRLATLGPGVMEGA--AETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGE 2714 R T G G + A A + + T A++ G + G ++G G Sbjct: 2627 --------KRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGP 2678 Query: 2715 QPTGQKGAS 2723 KG+S Sbjct: 2679 MALSSKGSS 2687 Score = 41.6 bits (96), Expect = 0.016 Identities = 108/439 (24%), Positives = 144/439 (32%), Gaps = 59/439 (13%) Query: 1089 RGEKRKEVELTQGPREDEPQKP--RKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGP 1146 R E +E + P P+ P K G+ +P+ S GRS Sbjct: 2046 RPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDST 2105 Query: 1147 SRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEE------------TRPSLDFP 1194 S S E ARE K A PS P+ PT +E RPSLDFP Sbjct: 2106 SDS-ELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFP 2164 Query: 1195 QEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTP-KPS 1253 A + + + P E RS P G L P P +RHD + Sbjct: 2165 ASAFGFSSLQPAPPQLPSPAEP-RSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKA 2223 Query: 1254 GSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPK 1313 SL ++ P SP+ LL +P A P ++ VA S + Sbjct: 2224 PSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTP--VISSVAERFSPSLEA 2281 Query: 1314 PSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFL------ 1367 S ++ G +PA + L P++ P + P D+ L Sbjct: 2282 AEQESGELDP-GMEPAAHSLWDL-TPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLEC 2339 Query: 1368 -EELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPG-------RAASP 1419 E KPS P S C + P P P AE E R A P Sbjct: 2340 SEAATEKPSPFQVP--SEDCAANGPTET---SPNPPGPAPAKAENEEAAACPAWERGAWP 2394 Query: 1420 PTLESSS-----LFPDLPV----DRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPY 1470 E SS L P+ PV PP S S ++G P CA P+ P+ Sbjct: 2395 EGAERSSRPDTLLSPEQPVCPAGGSGGPP--SSASPEVEAG-PQGCATEPR-------PH 2444 Query: 1471 PSFLLLEEVSPMLPSHFPD 1489 L ++P LP D Sbjct: 2445 RGELSPSFLNPPLPPSIDD 2463 Score = 40.8 bits (94), Expect = 0.027 Identities = 207/951 (21%), Positives = 297/951 (31%), Gaps = 252/951 (26%) Query: 1101 GPREDEPQK--PRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAARE 1158 GP P+ P + A D A +E G SP + ++ G E Sbjct: 1862 GPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKA--EGEREEE 1919 Query: 1159 GGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL- 1217 G + D+ S + K VP +++ T P P++ + +E + + E + Sbjct: 1920 GRAEAPDKSSHSSK----VPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMM 1975 Query: 1218 ----------RSPPAACAGEM---------------GASPGLLIPEQPPPSRHDTGTPKP 1252 R PP AG+ A L P P + DT T Sbjct: 1976 LTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSY 2035 Query: 1253 SGSLANTAPHGSSPTPGVGSLLGGPG-GTQAPVSHNSKDPPARQPGEFLAPVANPSSTAC 1311 + T P P P + L P +AP+ PP G L+ + S Sbjct: 2036 AALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLN--GNILSCSPDRRS--- 2090 Query: 1312 PKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELH 1371 PS S S + + + +K Q S PH P L Sbjct: 2091 --PSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSP---------TLW 2139 Query: 1372 PKPSARDAPPASSSCLCQDGEDAGSLEPQL--PRSPPGTAETEPGRAASPPTLESSSLFP 1429 P+ A +PP S G P L P S G + +P +PP L S Sbjct: 2140 PETEAHVSPPLDS--------HLGPARPSLDFPASAFGFSSLQP----APPQLPS----- 2182 Query: 1430 DLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD 1489 P + P GSL+ + D L A P + L+ P LPS P Sbjct: 2183 --PAEPRSAPC-GSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPS--PS 2237 Query: 1490 LSGGKVLSKTCPPERTVVPGAAPSL-PGKGSGCSVALMSHLSEDELEIQKLVTELESQLQ 1548 G +LS P A+P+L G S + ++S ++E Sbjct: 2238 SPGAPLLSNLPRP-------ASPALSEGSSSEATTPVISSVAE----------------- 2273 Query: 1549 RSKDTRGAPR-ELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTA 1607 R +P E AE ES EL G EP + S DLT + S A Sbjct: 2274 -----RFSPSLEAAEQES---GELDPGMEPAAH--------------SLWDLTPL--SPA 2309 Query: 1608 HREGAESAVATVEAVQGRPG-GTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHF 1666 + A+A ++ G G G PC L C++ +PF + Sbjct: 2310 PPASLDLALAPAPSLPGDMGDGILPCH----------LECSEAATEKPSPFQVPSED--- 2356 Query: 1667 QPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKE 1726 C A G + + P P+K + A C + ++P+ E Sbjct: 2357 -------------CAANGPTETSPNPPGPAPAKAENEE-----AAACPAWERGAWPEGAE 2398 Query: 1727 AASSQESEDSLRLLPCEQRGGFLP--------EPG-----TADQPHRGAPAPEAFGSPAV 1773 +S ++ S C G P E G T +PHRG +P P Sbjct: 2399 RSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLP 2458 Query: 1774 HLAPDLAFQ---------------------GDGAPPLDATWPFGASPSHAAQGHSAGRAG 1812 D G P D T P AS S ++Q S Sbjct: 2459 PSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDS----- 2513 Query: 1813 GHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSP 1872 + P E P+ + + +PV VS TH R DP P Sbjct: 2514 -DVPPE--------TEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDP---P 2561 Query: 1873 PIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPR-----VNPSGL--EGGTV----EGGK 1921 P+ Q P P SPPR +P GL E G V E K Sbjct: 2562 PLPQ---PDP------------------RPSPPRPDVCMADPEGLSSESGRVERLREKEK 2600 Query: 1922 VACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQ 1972 V + +PG + PA +L L G+ T G+G A++ Sbjct: 2601 VQGRVGRRAPGKAK----PASPARRLDLR--------GKRSPTPGKGPADR 2639 Score = 38.5 bits (88), Expect = 0.13 Identities = 60/276 (21%), Positives = 93/276 (33%), Gaps = 38/276 (13%) Query: 2 PGERPRG-APPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTT-------KGAREAGG 53 PGE G A ++ D ++AS P PS PP +TP ++ + +EA Sbjct: 972 PGEPALGEAEERCLSPDDSTVKMASPP--PSGPPSATHTPFHQSPVEEKSEPQDFQEADS 1029 Query: 54 QAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAE 113 P A + +KP G + PP RSP +A+ Sbjct: 1030 WGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEE-------KVPPPRSP---------QAQ 1073 Query: 114 GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG----LPRT 169 +P + I T T+ P + ++ E P GP GA PG LP+ Sbjct: 1074 EAP-----VNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQE 1128 Query: 170 EAQPAAEEL---GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPE 226 +P +E+ E S + + SP + P P P L +PE Sbjct: 1129 PGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPE 1188 Query: 227 YQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGS 262 S + E+ + V + P G+ Sbjct: 1189 VSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGT 1224 Score = 37.7 bits (86), Expect = 0.23 Identities = 184/849 (21%), Positives = 276/849 (32%), Gaps = 155/849 (18%) Query: 1502 PERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKD---TRGAPR 1558 P T + G PS+PG G E ++ ++LV E+ + Q SKD GA Sbjct: 568 PPSTAIQGTPPSVPGLGQ----------EEHVMKEKELVPEVPEE-QGSKDRGLDSGAET 616 Query: 1559 ELAEAESVGRVELGTGTEPPSQRRTCQATVPH--EDTFSAADLTRVGE---STAHREGAE 1613 E E ++ + P + + + P ED A+L + E S E A Sbjct: 617 E-EEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDAT 675 Query: 1614 SAVATVEAVQGRPGGTWPCPASFHPGHAALL----PCAQEDLVSGAPFSPRGANFHFQPV 1669 A + P P G L P + L + +P GA H + Sbjct: 676 KAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYI 735 Query: 1670 QK---AGASKTGLC--------QAEGDSRPPQ------DVCLPE-----PSKQPGPQLDA 1707 Q G S+T + E PP+ D+ PE + QP Sbjct: 736 QDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVP 795 Query: 1708 GSLAKC--SPDQELSFPKNKEAASSQESE---DSLRLLPCEQRGGFLPEPGTADQPHRGA 1762 + K +P+ EL++P N AA E E + + C++ F A Sbjct: 796 ATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSSF-------------A 842 Query: 1763 PAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRP 1822 + S A AP G + LD +S + A QG + G + PT+ Sbjct: 843 TSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLE 902 Query: 1823 GFEGNEFAPAGASSLTAP---------RGREAWLVPVPSPACVSNTHPSRR--SQ--DPA 1869 +G + P S+T +G +N S + SQ P Sbjct: 903 EDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPV 962 Query: 1870 LSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQG 1929 S P L P + ++++ L + T SPP PSG T P Sbjct: 963 FSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPP---PSGPPSATHT-------PFHQ 1012 Query: 1930 SPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTAN-------------QLQPE 1976 SP V+ + P Q EAD W G ++T G G + L+ E Sbjct: 1013 SP--VEEKSEP-----QDFQEADS-W---GDTKRTPGVGKEDAAEETVKPGPEEGTLEKE 1061 Query: 1977 NGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRE 2036 V P + + LTG T + L + + E EPT P E Sbjct: 1062 EKVPPPRSPQAQEAPVNIDEGLTGCT---IQLLPAQDKAIVFEIMEAGEPT--GPILGAE 1116 Query: 2037 SLALALTAAHSRSGSEG-----RTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTS 2091 +L L G R P+R+ SP A S+ L+ PSP + Sbjct: 1117 ALPGGLRTLPQEPGKPQKDEVLRYPDRSLSP-----------EDAESLSVLS--VPSPDT 1163 Query: 2092 AAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEAD 2151 A P P + R P Q L+ S EE+ Sbjct: 1164 ANQEPTPKSPCGLTEQYLHKDRWP-------------EVSPEDTQSLSLS------EESP 1204 Query: 2152 GVQATTDTGAED-SPVAPPSLTTSPCDPKEALAGCLLQGEG-SPLEDPSSWPPGSVSAVT 2209 + + D ++ SP + +L + + G L+Q E S P S P + + Sbjct: 1205 SKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATAS 1264 Query: 2210 CTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEA 2269 G T + I +DS K S ++P G P TP + Sbjct: 1265 PPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFS 1324 Query: 2270 QAGRGLPGP 2278 ++ LPGP Sbjct: 1325 KSPESLPGP 1333 Score = 35.4 bits (80), Expect = 1.1 Identities = 57/238 (23%), Positives = 84/238 (35%), Gaps = 36/238 (15%) Query: 36 EDNTPATRTTKGAREAGGQAQAMELPEAQPR---QARDGELKPPSLRGQAPSSTPGKRGS 92 ED + A+ T E G + ++ + P +A G PS +P+S+ + Sbjct: 847 EDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKG 906 Query: 93 PQTPPGRS-PLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVD 151 ++PP + S G G G++ R +E N ++ + Sbjct: 907 FKSPPCEDFSVTGESEKRGEIIGK-------GLSGERAVEEEEEETANVEMSEKLCSQYG 959 Query: 152 TPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPP 211 TP G L PG P A AEE RC S+ + PP GPP Sbjct: 960 TPVFSAPGHALHPGEP---ALGEAEE----RCLSPDDSTVKMAS---------PPPSGPP 1003 Query: 212 QSRGT----SPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPG 265 + T SP++ S P+ ADSW PG G A E + G G Sbjct: 1004 SATHTPFHQSPVEEKSEPQ-DFQEADSWGDTKRT--PGV--GKEDAAEETVKPGPEEG 1056 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 94.0 bits (232), Expect = 3e-18 Identities = 222/1002 (22%), Positives = 317/1002 (31%), Gaps = 198/1002 (19%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSP------------GHPSQPPLEDN----------- 38 P E P PP P ++ +SP P PP E++ Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512 Query: 39 TPATRTTKGAREAGGQAQAMELPEAQPRQA-------RDGELKPPSLRGQAPSSTPGKRG 91 +P + E + A+E P + P +A + L PP + P+S P + Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP--EELPTSPPPEAS 570 Query: 92 SPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQL--PE 149 PP SP+ P + + R S P +E+P +P EA++L P Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP 630 Query: 150 VDTPQGPGTG-APLRPG--------LPR-TEAQPAAEELGFHRCFQEPPSSFT-STNYTS 198 D+P P +P+ P LP + P EE +E P+S + S Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLS 690 Query: 199 PSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSF----PGANFGVPPAE 254 P P +P PP+ SP S + P E G + P E Sbjct: 691 PPPEDSPTSP-PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749 Query: 255 PEPIPKGSRPGGSPRG----VSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQ 310 P P+ P SP+ +S Q P L +P + A GP + QP+ Sbjct: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA-----EGPHLSP--QPE 802 Query: 311 GAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSD 370 P+P +P SP P + L+ S+ P +H +P Sbjct: 803 ELHLSPQTEEPHLSPVPEEPCLSPQP----EESHLSPQSEEPCLSPRPEESHLSPE---- 854 Query: 371 SLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAP 430 L K PE+PP PGQ P P + L P Sbjct: 855 -LEKPPLSPRPEKPPEE-------------------PGQC---------PAPEELPLFPP 885 Query: 431 GPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPT 490 P+ P L +P + PP PL + +G+PS +L P P P ++ Sbjct: 886 PGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITA 945 Query: 491 ARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP----------GPREKLPAVRSS 540 A +P + L L +P G +TP P P + Sbjct: 946 A--APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003 Query: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT 600 GSP A P+ PQ SP SL P + S LP Sbjct: 1004 SPGSPV---------GPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPL----- 1049 Query: 601 AGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTH 660 S S LSP+ E S P P T SP PSP S P Sbjct: 1050 --SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT-SPLPSPMGDLSCPA- 1105 Query: 661 YQPEPAKAF---------PFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPP 711 P PA A P DG+ A G+ P P + P L+G P P Sbjct: 1106 --PSPAPALDDFSGLGEDTAPLDGIDAPGS------QPEPGQTPGSLASELKGSPVLLDP 1157 Query: 712 YPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPP 771 A + ++V C+Q S Q P P Sbjct: 1158 E-------ELAPVTPMEVYPECKQTAGQGSPCE-------------------EQEEPRAP 1191 Query: 772 GLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASD 831 P+PP + +D + + + L GDA A L +P P Sbjct: 1192 VAPTPPTL--IKSD-----IVNEISNLSQGDASASFPGS-------EPLLGSPDPEGGGS 1237 Query: 832 LDMEDDAKLDSLITEALNGMEYQSDN-PEIDSSFI----DVFADEEPSGPRGPSSGHPLK 886 L ME D + +D+ PE D S + + + G +G P + Sbjct: 1238 LSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPAR 1297 Query: 887 SKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRS 928 S+ S + P + PR G G RGR + +S Sbjct: 1298 SRIKQGRSS--------SFPGRRRPRGGAHGGRGRGRARLKS 1331 Score = 82.4 bits (202), Expect = 8e-15 Identities = 238/1027 (23%), Positives = 338/1027 (32%), Gaps = 135/1027 (13%) Query: 77 SLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYI--------------- 121 ++R A TP PG +P P L +G P ++ Sbjct: 357 TIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEA 416 Query: 122 --LGIASSRTKPTL-----DETPENPQLEAAQL---PEVDTPQGPGTGAPLRPGLPRTEA 171 LG A + +P L +E P P E + L PE P + L P A Sbjct: 417 KPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA 476 Query: 172 QPAAEELGFHRCFQEPPSS---FTSTNYTSPSATP---------RPPAPGPPQSRGTSPL 219 P E L R +E P S S P ++P PP PP +PL Sbjct: 477 SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL 536 Query: 220 QPGS-----YPEYQASGADSWPPAAE---NSFPGANFGVPPAEPEPI--PKGSRPGGSPR 269 P P ++ S PP E + P A+ PP E P+ P P P Sbjct: 537 SPPPEASPLSPPFEESPLS--PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594 Query: 270 GVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQ 329 S FP + P P + + P P PE++ + P P Sbjct: 595 EASRL--FPPFEESPLSPPPEE---SPLSPPPEASRLSPP----PEDSPMSPPPEESPMS 645 Query: 330 PAP-----SPLPCYQ-----GQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKI 379 P P SPLP + L+ + S P A+ +P P DS + Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP-EDSPTSPPPED 704 Query: 380 LPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQ 439 P PP + LP P R+ G SP P + L+ P PQ Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ 764 Query: 440 LWDPTAAPYP------TPPGGPLAATRSMFFNGQPSPGQRLCLPQS-----APLPWPQVL 488 +P +P P P P + ++ + P P + PQ+ +P+P Sbjct: 765 AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE--- 821 Query: 489 PTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP--GPREKLPAVRSSQGGSP- 545 P P P + + P P + L + P PR + P Q +P Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPR---PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE 878 Query: 546 --ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP-PRVVGASPSESPLPSPATNTAG 602 LF G +P PL + +P +S G P L P P + SPS P SP Sbjct: 879 ELPLFPPPG--EPSLSPL---LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD 933 Query: 603 STCSSLSPMSSSPANPS-SEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHY 661 LSP+ ++ A P+ S +L P G P + P PP + T Sbjct: 934 PLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDP 993 Query: 662 QPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSS 721 +P P P P+ G A L E P P + + + L P+ PP +L Sbjct: 994 EPVPPMILP-PSPGSPVGPASPILME-PLPPQCSPLLQHSL--VPQNSPPSQCSPPALPL 1049 Query: 722 ASLDQLDVL--LTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAA 779 + L + + + + C L A G P+P A Sbjct: 1050 SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPA 1109 Query: 780 PRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAK 839 P + D +GL A +G D P G P TP L AS+L Sbjct: 1110 PAL--DDFSGLGEDT--------APLDGIDAP---GSQPEPGQTPGSL-ASEL-KGSPVL 1154 Query: 840 LDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKS----KAGVTPES 895 LD + ME + + EEP P P+ +KS + + Sbjct: 1155 LDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQG 1214 Query: 896 KAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFR 955 A P + P +P P G + LG++ + A +G + L Sbjct: 1215 DASASFPGSEPLLGSPD------PEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETD 1268 Query: 956 KDL--DSGGAAEG---SGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAP 1010 L D+G A G G G R+S R R G P R RRPR A G R Sbjct: 1269 DSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGR-RRPRGGAHGGRGRGRA 1327 Query: 1011 RVPRAAA 1017 R+ A+ Sbjct: 1328 RLKSTAS 1334 Score = 72.8 bits (177), Expect = 6e-12 Identities = 198/795 (24%), Positives = 259/795 (32%), Gaps = 152/795 (19%) Query: 1 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60 +P + P G P L+PR + P +P P PA GA G Q E Sbjct: 2171 VPSQDPFGLAPAY---PLEPRFPTAPPTYPPYPS-PTGAPAQPPMLGASSRPGAGQPGEF 2226 Query: 61 PEAQPRQAR------DGELKP--PSLRGQAPSSTPGKRGSPQTPPGRSP---------LQ 103 P R D LKP PSL A +PG G + P SP L+ Sbjct: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE 2286 Query: 104 APSRLAGRAEGS--PPQRYILGIASSRTK--------PTLDETPENPQLEAAQLPEVDTP 153 G + S PP + SS T P + + P P+ + P Sbjct: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE------P 2340 Query: 154 QGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGP--- 210 Q PG G LRP P A F+ P S+T Y P TPRP P P Sbjct: 2341 QSPGLG--LRPQEPPPAQALAPSPPSHPDIFR--PGSYTDP-YAQPPLTPRPQPPPPESC 2395 Query: 211 ----PQSRGTSPLQ--PGSYPEYQASGADSWPP---AAENSFPGA---------NFGVPP 252 P+S + P P S P+ Q+S P +AE P + PP Sbjct: 2396 CALPPRSLPSDPFSRVPAS-PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPP 2454 Query: 253 AEPE------PIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADV-AGHA--------- 296 + P+ P+ K RP P V+F+ A FPA + AG A Sbjct: 2455 SRPQSRDPFAPLHKPPRP--QPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512 Query: 297 -----FTNGPLVFAF---HQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348 F P AF P +AVG P QP P P G+N H Sbjct: 2513 GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP-------PHGINSH 2565 Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQD-GLGSTRGPPSSLPQRHFP 407 L P + + + + H S + + P + + GL R PPS LP Sbjct: 2566 FGPGPTLGKPQSTNYTVA--TGNFHPSGSPLGPSSGSTGESYGLSPLR-PPSVLPPPAPD 2622 Query: 408 GQA-YRASGVDTSPG--PPDTELAAPGP------PPARLPQLWDPTAAPYPTPP---GGP 455 G Y + G G P + PG A LP DP + Sbjct: 2623 GSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQ 2682 Query: 456 LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPT----ARPSPHGMEMLSRLPFPAGGP 511 R + Q ++A V P A PS E LSR P G Sbjct: 2683 RQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGT 2742 Query: 512 EWQGGSQGALGT--AGKTPGP----------REKLPAVRSSQ--------GGSPALFTYN 551 + + G + +G GP R PA SS GGS A Y Sbjct: 2743 QDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAF--YQ 2800 Query: 552 GMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPM 611 PG+ PL Q T + + A +P P GS + +S Sbjct: 2801 RAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTR 2860 Query: 612 SSSPANPSSEESQLPGPLGPSAFFHPPTHPQE----TGSPFPSPEPPHSLPTHY--QPEP 665 P P +PGP GP+ F + Q+ G+PFP PP P Y +P Sbjct: 2861 LPGPGEP------VPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR-PRFYPVSEDP 2913 Query: 666 AKAFPFPADGLGAEG 680 + P GL G Sbjct: 2914 HRLAPEGLRGLAVSG 2928 Score = 67.4 bits (163), Expect = 3e-10 Identities = 206/922 (22%), Positives = 296/922 (32%), Gaps = 183/922 (19%) Query: 420 PGPPDTELAAPGPPPARL-PQLWDPTAAPYPT---PPGGPLAATRSMFFNGQPSPGQRLC 475 PGP E G +L PQL P P P PL+ P RL Sbjct: 409 PGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLS 468 Query: 476 LP--QSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP-GPRE 532 P + P P+ L +RP +E P P P ++P P E Sbjct: 469 PPPEELPASPLPEALHLSRP----LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE 524 Query: 533 KLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP--HGTPSLPPPRVVGASP-- 588 + P SPAL T P A PL + +SP P+ PPP SP Sbjct: 525 ESPP-------SPALETPLS-PPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576 Query: 589 SESPLPSPATNTAGSTCSSLS----PMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQET 644 ESP+ P + S S P SP +P EES L P S PP Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS--- 633 Query: 645 GSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPF---PHEGP-----E 696 P PP P PE ++ P P + EE+P P E P E Sbjct: 634 ----PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP----EESPLSPPPEESPTSPPPE 685 Query: 697 VGRGGL--QGFPRAPPPY-----PTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAH 749 R + P +PPP P SL S L++ +L + S L+ Sbjct: 686 ASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745 Query: 750 RQFCGLLLARAKDGH----QRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQA 805 R L R ++ H P P P VP + H QA Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS-------------PQA 792 Query: 806 EGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFI 865 EG P L+ P L S ++ L + E +P+ + S + Sbjct: 793 EG----------PHLSPQPEELHLSP--QTEEPHLSPVPEEPCL-------SPQPEESHL 833 Query: 866 DVFADEEPSGPRGPSSGH--PLKSKAGVTPESKAPPPLPAATPDPQT----PRPGDRGC- 918 ++E PR P H P K ++P + PP P P P+ P PG+ Sbjct: 834 SPQSEEPCLSPR-PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLS 892 Query: 919 PARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGL 978 P G P G P L ++L + E S S L Sbjct: 893 PLLGEPALSEPGEPP-----------------LSPLPEELPLSPSGEPSLSPQLMPPDPL 935 Query: 979 RPRRNDGLGERPPPR--PRRPRTQAPGSRADPAPRVPRAAAL-------PEETRSSRRRR 1029 P + + PP P G++ D P P AA + P E + Sbjct: 936 PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEP 995 Query: 1030 LPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQ----------PPPR 1079 +PP P + G L+ + Q + L ++ ++ Q P P Sbjct: 996 VPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055 Query: 1080 GPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEA--------------------- 1118 P G+ E+ + + EP+ P + Sbjct: 1056 SP--IGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALD 1113 Query: 1119 -----GGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKD 1173 G D AP + + GS+P PG++P + A+ +G P D +AP Sbjct: 1114 DFSGLGEDTAPLDGIDAPGSQPEPGQTPGSL---------ASELKGSPVLLDPEELAPVT 1164 Query: 1174 PLQV-PTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASP 1232 P++V P +T+ + P +E +EP P + ++ + G+ AS Sbjct: 1165 PMEVYPECKQTAGQGSPC----EEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASAS- 1219 Query: 1233 GLLIPEQPPPSRHDTGTPKPSG 1254 P S G+P P G Sbjct: 1220 -------FPGSEPLLGSPDPEG 1234 Score = 62.4 bits (150), Expect = 9e-09 Identities = 130/552 (23%), Positives = 189/552 (34%), Gaps = 80/552 (14%) Query: 205 PPAPG-----PPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGAN------FGVPPA 253 PP PG PP + T + + P ++ AD + S PG + +PP Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166 Query: 254 EPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313 P +P P G + FP + P+P+ A P++ A +P Sbjct: 2167 VPAQVPSQD-PFGLAPAYPLEPRFPTAP-PTYPPYPSPTGAPA--QPPMLGASSRPGAGQ 2222 Query: 314 PEEAVGTGPAYPL--PTQPAPSPLP-CYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSD 370 P E T P P P+ P P P C + + G +S +P PF + Sbjct: 2223 PGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLL--SPPPFGE 2280 Query: 371 S---LHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTEL 427 S L ++ P LG P S H G + V +P P Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGT---HLGGLELKTPDVFKAPLTPRASQ 2337 Query: 428 AAPGPPPARL-PQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQ 486 P P L PQ P A P+PP P + + P P+ P P P+ Sbjct: 2338 VEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPP---LTPRPQPPP-PE 2393 Query: 487 VLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPA 546 P + SR+P P+ Q SQ L TP P S++ P+ Sbjct: 2394 SCCALPPRSLPSDPFSRVP---ASPQSQSSSQSPL-----TPRPL-------SAEAFCPS 2438 Query: 547 LFTYNGMT-DPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTC 605 T + DP ++P ++PQ P PPR P + A + A ++ Sbjct: 2439 PVTPRFQSPDPYSRP----PSRPQSRDPFAPLHKPPR-----PQPPEVAFKAGSLAHTSL 2489 Query: 606 SSLSPMSSSPANPSSE-ESQLPGPLGPS--------AFFHPP-----THPQETGSPFPSP 651 + ++ PA P+ E +++P P+ AF P T PQ G P P Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP 2549 Query: 652 E-------PPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHE---GPEVGRGG 701 PPH + +H+ P P P + A G F P G G Sbjct: 2550 PVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP 2609 Query: 702 LQGFPRAPPPYP 713 L+ PPP P Sbjct: 2610 LRPPSVLPPPAP 2621 Score = 61.6 bits (148), Expect = 1e-08 Identities = 157/627 (25%), Positives = 224/627 (35%), Gaps = 104/627 (16%) Query: 1686 SRPPQDVCL-PEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQ 1744 S PP++ L P P + P S P+ + P +++ +S EDSL LP E+ Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE 722 Query: 1745 RGGFLPEP------GTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGAS 1798 LP P ++ PH E SP P L+ Q + P L S Sbjct: 723 -SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE-EPHLSPQAE-EPHL--------S 771 Query: 1799 PSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVS- 1857 P A HL P A EG +P +P+ E L PVP C+S Sbjct: 772 PQPEEPCLCAVPEEPHLSPQA-----EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP 826 Query: 1858 ---NTHPSRRSQDPALSPPIRQLQL----------PGPGVAKSKDGILGLQELTPAAQSP 1904 +H S +S++P LSP + L P P + G E P P Sbjct: 827 QPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886 Query: 1905 --PRVNPSGLEGGTVEGGKVACGPAQG----SPGG--------VQVTTLPAVAGHQLGLE 1950 P ++P E E G+ P SP G + LP + Sbjct: 887 GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAA 946 Query: 1951 ADGHWGLLGQAEKTQG-QGTANQLQP------ENGVSPGGTDNHASVNASPKTALTGPTE 2003 A LG+ E G +G ++ P E +SP N P L P+ Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILP-PSP 1005 Query: 2004 GA-------VLLEKCKGSRAAMSLQEEAEPTPSPPSP-NRESLALALTAAHSRSGS---- 2051 G+ +L+E + + LQ P SPPS + +L L++ + S G Sbjct: 1006 GSPVGPASPILMEPLP-PQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGV 1064 Query: 2052 ------EGRTPERASSPGLNKPLLATGDSPAPS-VGDLAACAPSPTSAAHMPCSLG---- 2100 E+ S P L + SP PS +GDL+ APSP A LG Sbjct: 1065 SDEAELHEMETEKVSEPEC-PALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTA 1123 Query: 2101 PLPREDPLTS---PSRAQGGLGGQLPASPSCRDPPGPQQLLACSP--AWAPLEEADGVQA 2155 PL D S P + G L +L SP D P++L +P + ++ G + Sbjct: 1124 PLDGIDAPGSQPEPGQTPGSLASELKGSPVLLD---PEELAPVTPMEVYPECKQTAGQGS 1180 Query: 2156 TTDTGAED-SPVAPPSLTTSPCDPKEALAGCLLQGEGS-------PL---EDPSSWPPGS 2204 + E +PVAP T D ++ L QG+ S PL DP S Sbjct: 1181 PCEEQEEPRAPVAPTPPTLIKSDIVNEISN-LSQGDASASFPGSEPLLGSPDPEGGGSLS 1239 Query: 2205 VSAVTCTHSGDTPKDSTLRIPEDSRKE 2231 + T + +LR+ DS E Sbjct: 1240 MELGVSTDVSPARDEGSLRLCTDSLPE 1266 Score = 59.7 bits (143), Expect = 6e-08 Identities = 148/654 (22%), Positives = 207/654 (31%), Gaps = 111/654 (16%) Query: 895 SKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLF 954 S+ PP P TP T P +G+PK + + P Q + GK Sbjct: 370 SRFSPPEPGDTP---TDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQL 426 Query: 955 RKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPR 1014 L++ E L P L P P P +A SR P P Sbjct: 427 EPQLEAPLNEE---------MPLLPPPEESPLSPPPEESPTSPPPEA--SRLSPPPEELP 475 Query: 1015 AAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDE 1074 A+ LPE SR P P +E L + + + + S +E Sbjct: 476 ASPLPEALHLSRPLEESPLSPP----------PEESPLSPPPESSPFSPLEESPLSPPEE 525 Query: 1075 QPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSR 1134 PP E L+ P P + + + P +P P SR Sbjct: 526 SPP-------------SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP-PPEASR 571 Query: 1135 --PGPGRSPQARGPSRS-LETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSL 1191 P P SP + P S + A P + P P + + E S + P Sbjct: 572 LSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE 631 Query: 1192 DFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPK 1251 D P + PE + S P E R P + P P PPP T +P Sbjct: 632 DSPM-SPPPEESPMSPP-----PEVSRLSPLPVVSRLSPPPE-ESPLSPPPEESPT-SPP 683 Query: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPP-----------ARQPGEFL 1300 P S + P S +P P + +S ++ P R G L Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743 Query: 1301 AP-VANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVP----VAKKGPQPYSSPH-SE 1354 +P P + P+ LS + P VP ++ + P+ SP E Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803 Query: 1355 LFLGPKDLAGCFLEELH-----------PKPSARDAPPASSSCLCQDGEDAGSLEPQLPR 1403 L L P+ EE H P+P P S + L P+L + Sbjct: 804 LHLSPQ------TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857 Query: 1404 SP----PGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADP 1459 P P EPG+ +P E LFP PP SLS Sbjct: 858 PPLSPRPEKPPEEPGQCPAP---EELPLFP--------PPGEPSLS---------PLLGE 897 Query: 1460 PQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERT-VVPGAAP 1512 P + P +PP L E P+ PS P LS + PP + ++ AAP Sbjct: 898 PALSEPGEPPLSP---LPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948 Score = 58.9 bits (141), Expect = 9e-08 Identities = 240/1033 (23%), Positives = 324/1033 (31%), Gaps = 224/1033 (21%) Query: 1372 PKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDL 1431 P+P A +PP +++ G P +P G + + G P S PD Sbjct: 2108 PQPGALGSPPPAAAPTIFIGS---------PTTPAGLSTSADGFLKPPA---GSVPGPDS 2155 Query: 1432 PVDRFD--PPLYGSLSANRDSGLPFACA-----DPPQKTVPSD-PPYPSFLLLEEVSPML 1483 P + F PP + ++D PF A +P T P PPYPS PML Sbjct: 2156 PGELFLKLPPQVPAQVPSQD---PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPML 2212 Query: 1484 ----------PSHFPDLSGGKVLSKTCPPERTVVPG-------AAPSLPGKGSGCSVALM 1526 P F G + P+ + P A P PG G G Sbjct: 2213 GASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG------ 2266 Query: 1527 SHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQA 1586 + + L E L+ K+ GA + S G LG P S Sbjct: 2267 --KASEPLLSPPPFGESRKALEVKKEELGA-----SSPSYGPPNLGFVDSPSSGTHLGGL 2319 Query: 1587 TVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPC 1646 + D F A R + G Q P F PG Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPG------- 2372 Query: 1647 AQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLD 1706 + D + P +PR QP PP+ C P P Sbjct: 2373 SYTDPYAQPPLTPRP-----QPP------------------PPESCCALPPRSLPS---- 2405 Query: 1707 AGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPE 1766 D P + ++ SS +S + R L E F P P T P +P P Sbjct: 2406 ---------DPFSRVPASPQSQSSSQSPLTPRPLSAE---AFCPSPVT---PRFQSPDP- 2449 Query: 1767 AFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEG 1826 + P P D PL P A +AG H + G GF Sbjct: 2450 -YSRP-----PSRPQSRDPFAPLH-------KPPRPQPPEVAFKAGSLAHTSLGAGGFPA 2496 Query: 1827 NEFA-PAGASSLTAPRGREAWLVPVPSP-ACVSNTHPSRRS-----QDPALSPPIRQLQL 1879 A PAG P G+ V P A V P R + +P+L PP+ Q L Sbjct: 2497 ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL 2556 Query: 1880 PGPGVAKSKDG---ILGLQELTPAAQSPPRVNPSGLEGGTVEGGK-VACGPAQGSPGGVQ 1935 P P S G LG + T + +PSG G G + G + P V Sbjct: 2557 PPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL 2616 Query: 1936 VTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPK 1995 P + L A G+ EK + GT PG D P Sbjct: 2617 PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQD--------PG 2668 Query: 1996 TALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRT 2055 + TE LEK + + L + + +E+ A A A GS G Sbjct: 2669 MSGLSQTE----LEKQRQRQRLRELLIRQQIQRNTLRQEKET-AAAAAGAVGPPGSWGAE 2723 Query: 2056 PERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGP--LPREDPLTSPSR 2113 P SSP + L+ G +P D ++ P S P LGP P +D L+ P Sbjct: 2724 P---SSPAFEQ--LSRGQTPFAGTQDKSSLVGLPPSKLSGPI-LGPGSFPSDDRLSRPPP 2777 Query: 2114 AQGGLGGQLPASPSCRDPPGPQQLLACS---------PAWAPLEEA-----DGVQATTDT 2159 PA+PS D +QL+ S P PL++ QAT T Sbjct: 2778 ---------PATPSSMD-VNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAAT 2827 Query: 2160 GAEDSPVAPPSLTTSPCDPKEALAGCL------LQGEGSPLEDPSSWPPGSVSAVTCTHS 2213 + A T P ++AL L L G G P+ P+ G + H+ Sbjct: 2828 SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPA----GPAQFIELRHN 2883 Query: 2214 -------GDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTG 2266 G TP P+ R + E P R P G Sbjct: 2884 VQKGLGPGGTPFPGQ-GPPQRPRFYPVSEDPHRL----------------------APEG 2920 Query: 2267 DEAQAGRGLPGPDPQSRGAP---------PHTNPDRMPRGHSSYS-PSNTARLGHREGQA 2316 A GLP P + AP PHT +P G + P ++ LG A Sbjct: 2921 LRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLA 2980 Query: 2317 VTA--VPTEPPTL 2327 + A +P E P L Sbjct: 2981 LEAGKLPCEDPEL 2993 Score = 58.2 bits (139), Expect = 2e-07 Identities = 201/909 (22%), Positives = 288/909 (31%), Gaps = 150/909 (16%) Query: 602 GSTCSSLSPMSSSP----ANPSSE-----ESQLPGPLGPSAFFHPPTHPQETGSPFPSPE 652 G +S+ P P A P + E QL PL PP P+E+ P Sbjct: 398 GGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPP--PEES----PLSP 451 Query: 653 PPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCL------EETPFPHEGPEVGRGGLQGFP 706 PP PT PE ++ P P + L A + L EE+P E P Sbjct: 452 PPEESPTSPPPEASRLSP-PPEELPASPLPEALHLSRPLEESPLSPPPEES--------P 502 Query: 707 RAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQR 766 +PPP + L + L + + S L+ + Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP--------LSPPFEESPL 554 Query: 767 SPGPPGLPS--PPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP 824 SP P LP+ PP A R+ +S ++ P + P +P Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPE-------ESPMSPPPEASRLFPPFEESP 607 Query: 825 FPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEP-SGPRGPSSGH 883 P + + + L +P + S + +E P S P S Sbjct: 608 LSPPPEESPLSPPPEASRL-------------SPPPEDSPMSPPPEESPMSPPPEVSRLS 654 Query: 884 PLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGR 943 PL + ++P + P P P +P P +R P +P D+P+ Sbjct: 655 PLPVVSRLSPPPEESPLSPPPEESPTSPPPE----ASRLSPPPEDSPTSPPPEDSPASPP 710 Query: 944 QQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRT--QA 1001 + L L L E L PR + PRP P QA Sbjct: 711 PEDSLMSLPLEESPLLP--LPEEPQLCPRSEGPHLSPRPEE---PHLSPRPEEPHLSPQA 765 Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061 P P P A+PEE S + P P+ + +E L V ++ L Sbjct: 766 EEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824 Query: 1062 REYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGD 1121 S + P P E EL + P P+KP + Q Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPE------ESHLSPELEKPPLSPRPEKPPEEPGQ----- 873 Query: 1122 GAPANPEEPGGSRPG-PGRSPQARGPSRSL----------ETGAAAREGGPKCADRPSVA 1170 PA E P PG P SP P+ S E + G P + P + Sbjct: 874 -CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLS--PQLM 930 Query: 1171 PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAE-ESAPDSTEFTEALRSPPAACAGEMG 1229 P DPL P + + P+L E + P A+ +S P+S Sbjct: 931 PPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPL----------------- 973 Query: 1230 ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSK 1289 A+P L P PPP + T P+P P P+P G P G +P+ Sbjct: 974 AAPILETPISPPPEANCT-DPEP------VPPMILPPSP------GSPVGPASPILMEPL 1020 Query: 1290 DPPARQP--GEFLAPVANPSSTACPK--PSVLSSKISSFG-----CDPAGFNRDPLGVPV 1340 PP P L P +P S P P + S +S G D A + Sbjct: 1021 -PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS 1079 Query: 1341 AKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQ 1400 + P S S L P + P P+ D DG DA +P+ Sbjct: 1080 EPECPALEPSATSPL---PSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPE 1136 Query: 1401 LPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPP 1460 P PG+ +E SP L+ L P P++ +Y G P + P Sbjct: 1137 -PGQTPGSLASE--LKGSPVLLDPEELAPVTPME-----VYPECKQTAGQGSPCEEQEEP 1188 Query: 1461 QKTVPSDPP 1469 + V PP Sbjct: 1189 RAPVAPTPP 1197 Score = 57.8 bits (138), Expect = 2e-07 Identities = 118/509 (23%), Positives = 167/509 (32%), Gaps = 68/509 (13%) Query: 2026 PTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAAC 2085 P SP SP E+ L S E + L++PL + SP P L+ Sbjct: 453 PEESPTSPPPEASRL------SPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS-- 504 Query: 2086 APSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASP----SCRDPPGPQQLLACS 2141 P P S+ P E PL+ P + + P SP S PP + L+ Sbjct: 505 -PPPESSPFSPLE------ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPP 557 Query: 2142 PAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWP 2201 P P + E+SP++PP SP P + E SPL P Sbjct: 558 PEELPTSPPPEASRLSPP-PEESPMSPPP-EESPMSPPPEASRLFPPFEESPLSPPPEES 615 Query: 2202 PGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP--SVAVRATG 2259 P S + P+DS + P + R + P+ +SP + + Sbjct: 616 PLSPPP-EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674 Query: 2260 LSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYS-----------PSNTAR 2308 +PT +A R P P+ PP +P P S S P Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734 Query: 2309 LGHREGQAVTAVPTEPPTLQGAGPDSP-ACLEGEMGTSSKEPEDP---GTPETGR-SGAT 2363 EG ++ P EP P+ P + E S +PE+P PE S Sbjct: 735 CPRSEGPHLSPRPEEPHL--SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA 792 Query: 2364 KMPRVTCPSTGLGLGRTT-------APSSTASDFQSD----SPQSHRNASHQTPQGDPLG 2412 + P ++ L L T P Q + SPQS P+ L Sbjct: 793 EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLS 852 Query: 2413 PQDLKQRSRGYKKKPASTENGQWKG--QAPHGPVTCEVCAASFRSGPGLSRHKARKHRPH 2470 P+ K +KP E GQ + P P E + P LS Sbjct: 853 PELEKPPLSPRPEKPPE-EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE--------- 902 Query: 2471 PGAPAEPSPAALPAQQPLEPLAQKCQPPR 2499 P EP + LP + PL P + P+ Sbjct: 903 ---PGEPPLSPLPEELPLSPSGEPSLSPQ 928 Score = 50.4 bits (119), Expect = 3e-05 Identities = 137/577 (23%), Positives = 181/577 (31%), Gaps = 119/577 (20%) Query: 1107 PQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR---GPSRSLETGAAAREGGPKC 1163 PQ P + Q+ G APA P EP P P P++ GA++R G + Sbjct: 2165 PQVPAQVPSQDPFGL-APAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223 Query: 1164 ADRPSVAPKDPLQVPTNTETSEETR-PSLDFPQEAKEPETAEESAPDSTEFTEALRSPPA 1222 + + P P P+ + + R PSLD + P A +E L SPP Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKA------SEPLLSPPP 2277 Query: 1223 ACAG---------EMGAS------PGLLIPEQPPPSRHDTGTP--KPSGSLANTAPHGSS 1265 E+GAS P L + P H G P A P S Sbjct: 2278 FGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQ 2337 Query: 1266 ---PTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKIS 1322 +PG+G P QA P +PG + P A P T P+P S Sbjct: 2338 VEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP---PPPES 2394 Query: 1323 SFGCDPAGFNRDPLG-VPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHP--------- 1372 P DP VP + PQ SS S L P + P Sbjct: 2395 CCALPPRSLPSDPFSRVPAS---PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451 Query: 1373 ----KPSARD------APPA--------SSSCLCQDGEDAGSLEPQLPRSP--------- 1405 +P +RD PP + L AG LP P Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511 Query: 1406 ----------PGT----AETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSG 1451 PGT P R P + SL P +P PP ++++ G Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPP--HGINSHFGPG 2569 Query: 1452 LPFACADPPQKTVPSDPPYPSFLLLEE----------VSPM-----LPSHFPDLSGGKVL 1496 TV + +PS L +SP+ LP PD S + Sbjct: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLS 2629 Query: 1497 SKTCPPERTVVPGAAPSLPGKGSGCSVAL----------MSHLSEDELEIQKLVTELESQ 1546 P PG G G S+A MS LS+ ELE Q+ L Sbjct: 2630 HGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLREL 2689 Query: 1547 LQRSKDTRGAPRELAEAESVGRVELGT----GTEPPS 1579 L R + R R+ E + +G G EP S Sbjct: 2690 LIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSS 2726 Score = 49.7 bits (117), Expect = 6e-05 Identities = 143/595 (24%), Positives = 191/595 (32%), Gaps = 154/595 (25%) Query: 768 PGPPGLPSPPAAPRV---PADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP 824 PG G P P AAP + AGL + A FL G D P FL P Sbjct: 2110 PGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGEL-FLKLPPQVP 2168 Query: 825 FPLPASD-LDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGH 883 +P+ D + L EP P P + Sbjct: 2169 AQVPSQDPFGLAPAYPL-------------------------------EPRFPTAPPTYP 2197 Query: 884 PLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARG-------------RPKTRSL- 929 P S G + A PP+ A+ P +PG+ G +P+ SL Sbjct: 2198 PYPSPTG----APAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLD 2253 Query: 930 GLAPTEADAPSQGRQQR----------RGKQLKLFRKDLDSGGAAEG-----------SG 968 LA E+ G+ K L++ +++L + + G SG Sbjct: 2254 NLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSG 2313 Query: 969 SGGGG---------------RASGLRPRRNDGLGERP----------PPRPRRPRTQAPG 1003 + GG RAS + P+ + GLG RP P P P PG Sbjct: 2314 THLGGLELKTPDVFKAPLTPRASQVEPQ-SPGLGLRPQEPPPAQALAPSPPSHPDIFRPG 2372 Query: 1004 SRADP---APRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNR 1060 S DP P PR P E+ + LPPR P +R A + Q + Sbjct: 2373 SYTDPYAQPPLTPRPQPPPPESCCA----LPPRSLPSDPFSRVPASPQ-------SQSSS 2421 Query: 1061 LREYDFASESEEDEQPPPRGPGFRG--RRGRGEKRKE-----VELTQGPREDEPQKPRKA 1113 S E P P P F+ R R + L + PR P+ KA Sbjct: 2422 QSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKA 2481 Query: 1114 ---ARQEAGGDGAPA----------NPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGG 1160 A G G PA + + P G P RSP G + T + R Sbjct: 2482 GSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP---GTGAFVGTPSPMRFTF 2538 Query: 1161 PKCADRPSVAPKDP---LQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217 P+ PS+ P P L P + P+L PQ P Sbjct: 2539 PQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSG------- 2591 Query: 1218 RSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272 SP +G G S G L P +PP P P GSL + HG+S G+ S Sbjct: 2592 -SPLGPSSGSTGESYG-LSPLRPPSV---LPPPAPDGSLPYLS-HGASQRSGITS 2640 Score = 48.5 bits (114), Expect = 1e-04 Identities = 170/678 (25%), Positives = 228/678 (33%), Gaps = 154/678 (22%) Query: 21 RQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKP----P 76 R+V ++ P +DN A R K ++A Q +Q + G++ P Sbjct: 2050 RKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQIN---------KQTKVGDIARKTDRP 2100 Query: 77 SLRGQAPSSTPGKRGSPQTPPGRSPL------QAPSRLAGRAEG--SPPQRYILGIASSR 128 +L + P PG GSP PP +P P+ L+ A+G PP + G S Sbjct: 2101 ALHLRIPPQ-PGALGSP--PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG-PDSP 2156 Query: 129 TKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPP 188 + L P+ P AQ+P D P G PL P P PP Sbjct: 2157 GELFLKLPPQVP----AQVPSQD-PFGLAPAYPLEPRFPTA-----------------PP 2194 Query: 189 SSFTSTNYTSPSATP-RPPAPGPPQSRGTSPLQPGSY-------PEYQASGADSWP---- 236 T Y SP+ P +PP G G QPG + P +Q S D + Sbjct: 2195 ---TYPPYPSPTGAPAQPPMLGASSRPGAG--QPGEFHTTPPGTPRHQPSTPDPFLKPRC 2249 Query: 237 PAAEN----SFPGANFGV---PPAEPEPIPKG-------------SRPGGSPRGVSF-QF 275 P+ +N PG G P P P + S P P + F Sbjct: 2250 PSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDS 2309 Query: 276 PFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQP-APSP 334 P H + DV PL Q + P +G P P P Q APSP Sbjct: 2310 PSSGTHLGGLELKTPDVF-----KAPLTPRASQVEPQSP--GLGLRPQEPPPAQALAPSP 2362 Query: 335 LPCYQGQPGGLNRHSDL--SGALSSPGAAHS-APRPFSDSLHKSLTKILPERPPSAQDGL 391 H D+ G+ + P A PRP +S + P PS D Sbjct: 2363 -----------PSHPDIFRPGSYTDPYAQPPLTPRP-QPPPPESCCALPPRSLPS--DPF 2408 Query: 392 GSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP---PPARLPQLWDPTAA-- 446 P S P S P P +P P PP+R PQ DP A Sbjct: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR-PQSRDPFAPLH 2467 Query: 447 --PYPTPP-----GGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARP-----S 494 P P PP G LA T S+ G P+ LP +P+ +P S Sbjct: 2468 KPPRPQPPEVAFKAGSLAHT-SLGAGGFPA-----ALPAGPAGELHAKVPSGQPPNFVRS 2521 Query: 495 PHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLP---AVRSSQGGSPALFTYN 551 P G P P Q + +L K P P+ LP + S G P L Sbjct: 2522 P-GTGAFVGTPSPMRFTFPQAVGEPSL----KPPVPQPGLPPPHGINSHFGPGPTLGK-- 2574 Query: 552 GMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPM 611 Q + VA P G+P P G S SPL P+ + SL + Sbjct: 2575 ------PQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYL 2628 Query: 612 SSSPANPSSEESQLPGPL 629 S + +S+ S + P+ Sbjct: 2629 S----HGASQRSGITSPV 2642 Score = 47.4 bits (111), Expect = 3e-04 Identities = 225/941 (23%), Positives = 290/941 (30%), Gaps = 209/941 (22%) Query: 1688 PPQDVCLPEPSKQPGPQLDAGSLA-----KCSPDQELSFPKNKEAASSQESEDSLRLLPC 1742 PPQ L P P + GS S D L P E L+L P Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP- 2165 Query: 1743 EQRGGFLPEPGTADQPHRGAPAPEAFG-SPAVHLAPDLAFQGDGAPPLDATWPFGASPSH 1801 Q P+ + FG +PA L P APP T+P SP+ Sbjct: 2166 --------------QVPAQVPSQDPFGLAPAYPLEPRFPT----APP---TYPPYPSPTG 2204 Query: 1802 AAQGHSAGRAGGHLHPTAGRPGFEGNEF--APAGASSLTAPRGREAWLVPVPSPACVSNT 1859 A G P AG+PG EF P G PR + + P P C S Sbjct: 2205 APA--QPPMLGASSRPGAGQPG----EFHTTPPGT-----PRHQPSTPDPFLKPRCPSLD 2253 Query: 1860 HPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPS--GLEGGTV 1917 + L+ P + PG G K+ + +L SPP S LE Sbjct: 2254 N---------LAVP----ESPGVGGGKASEPLL----------SPPPFGESRKALEVKKE 2290 Query: 1918 EGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPEN 1977 E G A P+ G P + P+ H GLE K A+Q++P+ Sbjct: 2291 ELG--ASSPSYGPPN-LGFVDSPSSGTHLGGLELK-----TPDVFKAPLTPRASQVEPQ- 2341 Query: 1978 GVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRES 2037 SPG + A + P+ + GS Q P P PP P Sbjct: 2342 --SPGLGLRPQEPPPAQALAPSPPSHPDIFRP---GSYTDPYAQPPLTPRPQPPPPES-- 2394 Query: 2038 LALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPC 2097 AL S R P S ++ L +P P + A PSP + P Sbjct: 2395 -CCALPPRSLPSDPFSRVPASPQSQSSSQSPL----TPRPLSAE--AFCPSPVT----PR 2443 Query: 2098 SLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEA--DGVQA 2155 P DP + P P+ P RDP P L P P E A G A Sbjct: 2444 FQSP----DPYSRP-----------PSRPQSRDPFAP---LHKPPRPQPPEVAFKAGSLA 2485 Query: 2156 TTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGD 2215 T GA P A P+ K PS PP V + Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKV----------------PSGQPPNFVRSPGTGAFVG 2529 Query: 2216 TPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGL 2275 TP SP R T P G S V GL P G + G G Sbjct: 2530 TP------------------SPMRFTFPQAVGEPSLKPPVPQPGLPP-PHGINSHFGPGP 2570 Query: 2276 PGPDPQSRG---APPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTL----- 2327 PQS A + +P P G SS S + L +V P +L Sbjct: 2571 TLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSH 2630 Query: 2328 ---QGAGPDSPACLEGE----MGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRT 2380 Q +G SP + MG+S E PGT + G SG ++ Sbjct: 2631 GASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELL 2690 Query: 2381 TAPSSTASDFQSDSPQSHRNASHQTPQG----DPLGPQDLKQRSRGYKKKPASTENGQWK 2436 + + + + A P G +P P +Q SRG + + Sbjct: 2691 IRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPA-FEQLSRGQTPFAGTQDKSSLV 2749 Query: 2437 GQAPH---GPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPS--------------- 2478 G P GP+ GPG R RP P PA PS Sbjct: 2750 GLPPSKLSGPIL----------GPGSFPSDDRLSRPPP--PATPSSMDVNSRQLVGGSQA 2797 Query: 2479 -------PAALPAQQPLEPLAQKCQPPRKKSHRVSGKER-PNHSRGDPSHVTQPPPAQGS 2530 P +LP QQ + L Q+ Q S R + R P+ + P G Sbjct: 2798 FYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGI 2857 Query: 2531 KEVLRAPGSPHSQQLHPPSPTEHEVDVKT---PASKPRPDQ 2568 L PG P P E +V+ P P P Q Sbjct: 2858 STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQ 2898 Score = 47.0 bits (110), Expect = 4e-04 Identities = 116/500 (23%), Positives = 176/500 (35%), Gaps = 100/500 (20%) Query: 845 TEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPP---L 901 T L G E + +P + S A E PS G PL G TPES A P Sbjct: 4018 TLLLTGKEQNTVDPAVSSE-----ATEGPS----THQGGPLA--IGTTPESMATEPGEVK 4066 Query: 902 PAATPDPQT----PRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKD 957 P+ + D Q P+P +P+ SL L P G+QQ++ L Sbjct: 4067 PSLSGDSQLLLVQPQP---------QPQPSSLQLQPP---LRLPGQQQQQVSLLHT---- 4110 Query: 958 LDSGGAAEGS-GSGGGGRASG---LRPRRNDGLGERPPPR------PRRPRTQAPGSRAD 1007 +GG + G GSG AS L + + LG++P P++P + P + + Sbjct: 4111 --AGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERP-MQNN 4167 Query: 1008 PAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGG-AWGKELILKIVQQKNRLREYDF 1066 P+ P+ + + + + P + + +G A +L QQ+ +L+ Sbjct: 4168 TGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227 Query: 1067 ASESEEDEQ----PPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDG 1122 + ++ + PP + PG + QG +PQ G G Sbjct: 4228 QRQLQQSQAVRQTPPYQEPG-----------TQTSPLQGLLGCQPQL--------GGFPG 4268 Query: 1123 APANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTE 1182 P + G+ P P P+ P +L TG P PK P Q+P+ Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--- 4325 Query: 1183 TSEETRPSLDFPQEAKEPET---AEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQ 1239 PS P EA+ P T + + E SP AA + S GL Sbjct: 4326 ------PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGL----- 4374 Query: 1240 PPPSRHDTGTPKPSGSLANT-APHGSSPTPGVGSLLGG---PGGTQAPVSHNSKDPPARQ 1295 G P +LA T P SS PG + G P +Q + ++ P Sbjct: 4375 --------GPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCAL 4426 Query: 1296 PGEFLAPVANPSSTACPKPS 1315 + + AN P S Sbjct: 4427 GAQSVKREANGEPIGAPGTS 4446 Score = 45.8 bits (107), Expect = 8e-04 Identities = 104/412 (25%), Positives = 148/412 (35%), Gaps = 52/412 (12%) Query: 327 PTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS 386 P Q + G P +H GAL G +++ +++ E P + Sbjct: 3987 PQQQQQQQVALGPGMPAKPLQHFSSPGAL---GPTLLLTGKEQNTVDPAVSSEATEGPST 4043 Query: 387 AQDG---LGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDP 443 Q G +G+T ++ P P + + + P P + PP RLP Sbjct: 4044 HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQ 4103 Query: 444 TAAPYPTPPGGP-----------------LAATRSMFFNGQP-SPGQRLCLPQSAPLPWP 485 + T GG L A S+ QP S Q L PQ L P Sbjct: 4104 QVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERP 4163 Query: 486 QVLPTA-RPSPHGMEMLSRLPFPAGG-----PEWQGGSQGALGTAGK----TPGPREKLP 535 T +P G + S P G + + QG L + +P +++L Sbjct: 4164 MQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223 Query: 536 AVRSSQG--GSPALFTYNGMTDPGAQ--PL--FFGVAQPQVSPHGTPSLPPPRVVGASPS 589 A+ + S A+ +PG Q PL G QPQ+ P P + +GA P Sbjct: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLG-CQPQLGGFPGPQTGPLQELGAGPR 4282 Query: 590 -ESPLPSPATNTAGSTCSSLSPMSSSPANPSSEE----SQLPGPLG--PSAFFHPPTHPQ 642 + P PA A ST L P+ +P S +E SQLP P P+ PPTHP Sbjct: 4283 PQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPG 4342 Query: 643 ETGSPFPSPEPPHSLPTHYQPEPAK-AFPFPADGLGAEGAFQCLEETPFPHE 693 P+ EPP P P A+ A + GLG L ET P + Sbjct: 4343 TPKPQGPTLEPP---PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQ 4391 Score = 44.3 bits (103), Expect = 0.002 Identities = 107/448 (23%), Positives = 141/448 (31%), Gaps = 60/448 (13%) Query: 2471 PGAPAEPSPAALPAQQPLEP-LAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQG 2529 P +P E SP + P + P P L PP + S E S T PPP Sbjct: 511 PFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP--- 567 Query: 2530 SKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKR-----EG 2584 E R P + PP P E + AS+ P E L P E E Sbjct: 568 --EASRLSPPPEESPMSPP-PEESPMSPPPEASRLFPP-FEESPLSPPPEESPLSPPPEA 623 Query: 2585 RRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYA 2644 R P DSP + + RL S LPV + + S SP Sbjct: 624 SRLSPPPE-DSPMSPPPEESPMSPPPEVSRL---SPLPVVSRLSPPPEESPLSPPPEESP 679 Query: 2645 ASPSHCLSVEGGPEADG--EQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRML 2702 SP S P D PP + P E +L E+ P + L Sbjct: 680 TSPPPEASRLSPPPEDSPTSPPPEDSPASP-----PPEDSLMSLPLEESPLLPLPEEPQL 734 Query: 2703 CPGRMDGAALGEQPT-------------GQKGASARGFWGPRETKALGVCKESGSEPAED 2749 CP R +G L +P + P E V +E P + Sbjct: 735 CP-RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAE 793 Query: 2750 SSRAHSRSEEGVWEENT--PPLGPLGF-PETSSSPADSTTSS-----CLQGLPD----NP 2797 + EE T P L P+ P S P +S S CL P+ +P Sbjct: 794 GPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSP 853 Query: 2798 DTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGR--LTRKRNPHVYGKRCE 2855 + + P P P L LFPP G L+ + E Sbjct: 854 ELEKPPLSPRPEKPPEEPGQCPAPEEL--------PLFPPPGEPSLSPLLGEPALSEPGE 905 Query: 2856 KPVLPLPTQPSFEEGGDPTLGPARLPTD 2883 P+ PLP + G+P+L P +P D Sbjct: 906 PPLSPLPEELPLSPSGEPSLSPQLMPPD 933 Score = 43.9 bits (102), Expect = 0.003 Identities = 74/305 (24%), Positives = 110/305 (36%), Gaps = 39/305 (12%) Query: 3636 TFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSL---APGELARGTENGMK 3692 T GS T PAG +S+ P+ ++ P P + L P ++ G+ Sbjct: 2123 TIFIGSPTTPAGLSTSAD--GFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLA 2180 Query: 3693 PATPKAKPGPSSQGSGSPRPGTKTGGGSQP-------QPASGQLQSETATTPAKPSFPSR 3745 PA P P++ + P P + TG +QP +P +GQ T P P Sbjct: 2181 PAYPLEPRFPTAPPTYPPYP-SPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPS 2239 Query: 3746 SPAPERLPARAQAKSCT--KGPREAGEQGPHGSLGPKEKGES----STKRKKGQVPGPAR 3799 +P P P + + P G + L P GES K+++ P+ Sbjct: 2240 TPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSY 2299 Query: 3800 SESVGSFGRAPSA-----------PD--KPPRTPR----KQATPSRVLPTKPKPNSQNKP 3842 F +PS+ PD K P TPR + +P L + P +Q Sbjct: 2300 GPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALA 2359 Query: 3843 RPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAE-PAEPHTHRTAEAQS 3901 PPS PG D + RP PP+ A+ P++P + A QS Sbjct: 2360 PSPPSHPDIFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQS 2417 Query: 3902 DLLSQ 3906 SQ Sbjct: 2418 QSSSQ 2422 Score = 43.9 bits (102), Expect = 0.003 Identities = 66/253 (26%), Positives = 94/253 (37%), Gaps = 31/253 (12%) Query: 3547 LERPENEAS---PGSPGPLLQ--QALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGA 3601 LERP + P PGP+LQ Q LP +P G +G A + P Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA--------KNPQL 4211 Query: 3602 RGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA----GCQSSSKDRSA 3657 R +P Q+ L ++++ S V + P G+ T P GCQ Sbjct: 4212 R-HLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQ--EPGTQTSPLQGLLGCQPQLGGFPG 4268 Query: 3658 AST-PSKALKFPVHPRKAVGSLAP-GELARGTENG-MKPATPKAKPGPSSQGSGSPRPGT 3714 T P + L P+ AP G L+ G G + P P + P + S P P + Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328 Query: 3715 KTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPH 3774 + P QL TP KP P+ P P R+ A + T + G P Sbjct: 4329 QL-------PTEAQLPPTHPGTP-KPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380 Query: 3775 GSLGPKEKGESST 3787 +L +K E S+ Sbjct: 4381 DNLAETQKPEQSS 4393 Score = 42.7 bits (99), Expect = 0.007 Identities = 71/265 (26%), Positives = 93/265 (35%), Gaps = 31/265 (11%) Query: 1217 LRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTP------KPSGSLANTAPHGSSPTPGV 1270 L+ PP A P L P P R T P P+G+ A G+S PG Sbjct: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA 2220 Query: 1271 GSLLGGPGGTQAPVSHNSKDPPARQPGEFLAP-VANPSSTACPK-PSVLSSKISSFGCDP 1328 G PG + P+ P FL P + + A P+ P V K S P Sbjct: 2221 GQ----PGEFHTTPPGTPRHQPST-PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSP 2275 Query: 1329 AGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDL--AGCFLEELHPK-PSARDAPPASSS 1385 F + V K+ S + LG D +G L L K P AP + Sbjct: 2276 PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335 Query: 1386 CLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDL--PVDRFDPPLYGS 1443 + L PQ P PP A A SPP+ PD+ P DP Sbjct: 2336 SQVEPQSPGLGLRPQEP--PPAQA-----LAPSPPS------HPDIFRPGSYTDPYAQPP 2382 Query: 1444 LSANRDSGLPFACADPPQKTVPSDP 1468 L+ P +C P +++PSDP Sbjct: 2383 LTPRPQPPPPESCCALPPRSLPSDP 2407 Score = 42.4 bits (98), Expect = 0.009 Identities = 116/486 (23%), Positives = 148/486 (30%), Gaps = 78/486 (16%) Query: 3455 APGPGED--RPPPRGS--SPILSE---GSLPALLHLCSEVAPSTTKGWPETLERPVDPVT 3507 +P P E PPP S SP E LP LHL + S PE P + Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509 Query: 3508 HPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSP----GPLL 3563 P P PP SP AL P EASP SP PL Sbjct: 510 SPFS----PLEESPLSPPEESPPSPALETPLS----------PPPEASPLSPPFEESPLS 555 Query: 3564 QQALPLGASLPRPGAR--GQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHL------ 3615 L S P +R E +P P R P F+E L Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP-FEESPLSPPPEE 614 Query: 3616 --LQKEKEVSSSHMVSEGGPRGTFHKGSATKP------------AGCQSSSKDRSAASTP 3661 L E S E P + S P S + S S P Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674 Query: 3662 SKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQ 3721 + + P P L+P + P A P P P + Sbjct: 675 PE--ESPTSPPPEASRLSPPP--EDSPTSPPPEDSPASPPPEDSLMSLPLEESPL----L 726 Query: 3722 PQPASGQL--QSETATTPAKPSFPSRSPAPER--LPARAQAKSCTKGPRE----AGEQGP 3773 P P QL +SE +P P SP PE L +A+ + P E A + P Sbjct: 727 PLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786 Query: 3774 HGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPT- 3832 H L P+ +G + + + P E P P P+ +P P Sbjct: 787 H--LSPQAEGPHLSPQPEELHLSPQTEEP--HLSPVPEEPCLSPQPEESHLSPQSEEPCL 842 Query: 3833 KPKPNS-------QNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHG 3885 P+P + P P E+ EPG + L P G P L P A+ Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL-- 900 Query: 3886 AEPAEP 3891 +EP EP Sbjct: 901 SEPGEP 906 Score = 42.4 bits (98), Expect = 0.009 Identities = 60/214 (28%), Positives = 78/214 (36%), Gaps = 28/214 (13%) Query: 3693 PATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSET--ATTPAKPSFPSRSP-AP 3749 PA+P+++ SSQ +PRP + P P + + QS + P++P SR P AP Sbjct: 2412 PASPQSQS--SSQSPLTPRP--LSAEAFCPSPVTPRFQSPDPYSRPPSRPQ--SRDPFAP 2465 Query: 3750 ERLPARAQA-----KSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVG 3804 P R Q K+ + G G +L GE K GQ P RS G Sbjct: 2466 LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTG 2525 Query: 3805 SFGRAPSA-----PDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQR 3859 +F PS P K P LP NS P P +P T Sbjct: 2526 AFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGP-----TLGKPQSTNY 2580 Query: 3860 KDRLGKAFPQGRPLLRPPKRGTA--VHGAEPAEP 3891 G P G PL P G+ +G P P Sbjct: 2581 TVATGNFHPSGSPL--GPSSGSTGESYGLSPLRP 2612 Score = 40.8 bits (94), Expect = 0.027 Identities = 163/808 (20%), Positives = 279/808 (34%), Gaps = 185/808 (22%) Query: 1055 VQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQK----- 1109 +QQ+ +L++ + ++ + + + ++ + +++++ + Q ++ + Q+ Sbjct: 3920 LQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLN 3979 Query: 1110 -------PRKAARQEAG-GDGAPANP----EEPGGSRPG---PGRSPQARGPSRSLET-- 1152 P++ +Q+ G G PA P PG P G+ P+ S E Sbjct: 3980 QSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039 Query: 1153 GAAAREGGPKCAD-------------RPSVAPKDPLQV----PTNTETSEETRPSLDFPQ 1195 G + +GGP +PS++ L + P +S + +P L P Sbjct: 4040 GPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPG 4099 Query: 1196 EAKEP-------------ETAEESAPDSTEFTEALRSPPAACAGEMGA-SPGLLIPEQPP 1241 + ++ + S+ +++ L P + + G+ + LL P+QP Sbjct: 4100 QQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPM 4159 Query: 1242 ---PSRHDTGT--PKPSGSL-ANTAPHGSSPTPGVGSLLGGPGGTQA--PVSHNSKDPPA 1293 P +++TG PKP L + G P VG L G A P + Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219 Query: 1294 RQPGEFLAPVANPSSTAC------PKPSVLSSKISSF-GCDP--AGFNR------DPLGV 1338 +Q L S A +P +S + GC P GF LG Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGA 4279 Query: 1339 PVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKP--SARDAP------PASSSCLCQD 1390 +GP +P L GP L +HP P S+ P P+ SS L + Sbjct: 4280 GPRPQGPPRLPAPPGALSTGP------VLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTE 4333 Query: 1391 GE----DAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSA 1446 + G+ +PQ P P P A TL S L P Sbjct: 4334 AQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGP----------------- 4376 Query: 1447 NRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSG------GKVLSKTC 1500 DPP + P E S ++P H ++G ++ K Sbjct: 4377 ----------WDPPDNLAETQKP--------EQSSLVPGHLDQVNGQVVPEASQLSIKQE 4418 Query: 1501 PPERTVVPGA--------APSLPGKGSGCSVALMSHLSE-DELEIQKLVTELESQLQRSK 1551 P E GA + G+ + L SE L +QKL+ QL + Sbjct: 4419 PREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGR 4478 Query: 1552 DTRGAPREL---AEAESVGRVELGTGTEPPSQRRTCQATVP----HEDTFSAAD-LTRVG 1603 + G E+ +++ G + GT PS + A P + A+D L Sbjct: 4479 GSEGLRAEINGHIDSKLAGLEQKLQGT--PSNKEDAAARKPLTPKPKRVQKASDRLVSSR 4536 Query: 1604 ESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSG----APFS- 1658 + +G ++ A ++ ++ +LLP + + + APF Sbjct: 4537 KKLRKEDGVRASEALLKQLK---------------QELSLLPLTEPAITANFSLFAPFGS 4581 Query: 1659 --PRGANFHFQPVQKAGASKTG------LCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSL 1710 P + +GA TG L S PP P+ P P + + Sbjct: 4582 GCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPT--PPPSVQQKMV 4639 Query: 1711 AKCSPDQELSFPKNKEAASSQESEDSLR 1738 +P +EL K+AAS+++SE +LR Sbjct: 4640 NGVTPSEELG-EHPKDAASARDSERALR 4666 Score = 40.4 bits (93), Expect = 0.035 Identities = 86/374 (22%), Positives = 121/374 (32%), Gaps = 60/374 (16%) Query: 3537 GRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKR 3596 G+ L+ LE P NE P P P + PL P P E +P + + Sbjct: 420 GKAGVQLEPQLEAPLNEEMPLLPPP---EESPLS---PPP------EESPTSPPPEASRL 467 Query: 3597 RAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRS 3656 P +P E L + E S E P + S P + S Sbjct: 468 SPPPEELPASP--LPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL--EESPLSPP 523 Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKT 3716 S PS AL+ P+ P L+P E+ + P + P + S P ++ Sbjct: 524 EESPPSPALETPLSPPPEASPLSPPF----EESPLSPPPEELPTSPPPEASRLSPPPEES 579 Query: 3717 GGGSQPQPASGQLQSETATTPAKPSFPSR--SPAPERLPARAQAKSCTKGPREAGEQGPH 3774 P P + + P F SP PE P P EA P Sbjct: 580 P--MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP--------PPEASRLSPP 629 Query: 3775 GSLGPKEKGESSTKRKKGQVPGP--ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPT 3832 P++ S + P P +R + R P++ P +P P PT Sbjct: 630 ----PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP-----PPEESPT 680 Query: 3833 KPKPNS-------QNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPK------R 3879 P P + ++ P PP E A P +D L + PLL P+ R Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASP---PPEDSLMSLPLEESPLLPLPEEPQLCPR 737 Query: 3880 GTAVH-GAEPAEPH 3892 H P EPH Sbjct: 738 SEGPHLSPRPEEPH 751 Score = 40.4 bits (93), Expect = 0.035 Identities = 29/83 (34%), Positives = 34/83 (40%), Gaps = 3/83 (3%) Query: 590 ESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHP--QETGSP 647 ESP P P T + + S + A P E S P PL PS PPT P + P Sbjct: 4882 ESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP-ASPPTEPLVELPTEP 4940 Query: 648 FPSPEPPHSLPTHYQPEPAKAFP 670 P P LP PE A+ P Sbjct: 4941 LAEPPVPSPLPLASSPESARPKP 4963 Score = 39.7 bits (91), Expect = 0.060 Identities = 73/330 (22%), Positives = 113/330 (34%), Gaps = 74/330 (22%) Query: 3619 EKEVSSSHM-----VSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP-VHPR 3672 +K++ + H+ +E R +G P G + + AS P A P V P+ Sbjct: 3062 KKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPK 3121 Query: 3673 KAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSG-SPRPGTKTGGGSQPQPASGQLQS 3731 G P ATPK +P P++ G +PG G + +G S Sbjct: 3122 VEEGGRHPSPCQ------FTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSS 3175 Query: 3732 ETAT-----------------TPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ--G 3772 T TP+ S P S E+ + A + GP +G++ Sbjct: 3176 SGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDK 3235 Query: 3773 PHGSLGPKE---------KGESSTKRKKGQV----------------------PGPARSE 3801 SL E + E +KK Q+ PGPA++ Sbjct: 3236 MESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAM 3295 Query: 3802 SVGSFGRAPSAPDKPPRT------PRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 S+ G +PS + R+ P ++PT+P P + R PS + G Sbjct: 3296 SLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQP-PAHALQQRLAPSMAMVSNQG 3354 Query: 3856 HTQRKDRLGKA--FPQ--GRPLLRPPKRGT 3881 H G+A PQ +P+L GT Sbjct: 3355 HMLSGQHGGQAGLVPQQSSQPVLSQKPMGT 3384 Score = 36.2 bits (82), Expect = 0.66 Identities = 92/426 (21%), Positives = 125/426 (29%), Gaps = 53/426 (12%) Query: 3458 PGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPS 3517 P E+ PP LS + L E +P + P E P P R P Sbjct: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLS----PPPEELPTSPPPEASRLSPPPE 577 Query: 3518 NHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPG 3577 PPP SP R + + P E SP SP P + P P Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637 Query: 3578 ARGQDAEG------KRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEG 3631 + + +PL + P +P E+ E S E Sbjct: 638 PPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP--PEESPTSPPPEASRLSPPPED 695 Query: 3632 GPRGTFHKGSATKPAGCQSSSKDRSAASTP---SKALKFPVHPRKAVGSLAPGELARGTE 3688 P + S P + S S P S L P P+ S P R E Sbjct: 696 SPTSPPPEDSPASPP------PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749 Query: 3689 NGMKPATPKAKPGPSSQGSG-SPRPGTKT---------------GGGSQPQPASGQL--Q 3730 + P + P ++ SP+P G PQP L Q Sbjct: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ 809 Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPR----------EAGEQGPHGSLGPK 3780 +E P P SP PE Q++ PR E P P+ Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPE 869 Query: 3781 EKGESSTKRKKGQVPGPARSESVGSFGR-APSAPDKPPRTPRKQATPSRVLPTKPKPNSQ 3839 E G+ + P P G A S P +PP +P + P L +P+ Sbjct: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELP---LSPSGEPSLS 926 Query: 3840 NKPRPP 3845 + PP Sbjct: 927 PQLMPP 932 Score = 36.2 bits (82), Expect = 0.66 Identities = 73/305 (23%), Positives = 107/305 (35%), Gaps = 68/305 (22%) Query: 3617 QKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQS--SSKDRSAASTPSKALKFPVHPRKA 3674 Q++++VS H GG G GS+++ + + S P + + P++ Sbjct: 4100 QQQQQVSLLHTAG-GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQP 4158 Query: 3675 VGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA 3734 + L R +N P PK PGP Q SG PG P GQL+++ Sbjct: 4159 M-------LERPMQNNTGPQPPK--PGPVLQ-SGQGLPGVGI------MPTVGQLRAQLQ 4202 Query: 3735 TTPAK-PSFPSRSPAPE---------RLPARAQAKSCTKGPREAGEQG------------ 3772 AK P SP + R ++QA T +E G Q Sbjct: 4203 GVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQ 4262 Query: 3773 ----PHGSLGP-KEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPS 3827 P GP +E G + ++P P + S G P P PP +P++ PS Sbjct: 4263 LGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPV-LGPVHPTPPPSSPQEPKRPS 4321 Query: 3828 RV-------------LPTKPKPNSQNKP--RPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 ++ PT P P PPP + P Q D L F +G Sbjct: 4322 QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPG---RVSPAAAQLADTL---FSKGLG 4375 Query: 3873 LLRPP 3877 PP Sbjct: 4376 PWDPP 4380 Score = 35.8 bits (81), Expect = 0.86 Identities = 74/355 (20%), Positives = 117/355 (32%), Gaps = 33/355 (9%) Query: 2235 ESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGA---PPHTNP 2291 E P PLA +P G ++Q P P PQ PP P Sbjct: 4039 EGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLP 4098 Query: 2292 DRMPRGHS---SYSPSNTARLGHREGQAVTAVP---TEPPTLQGAGPDSPACLEGEMGTS 2345 + + S + + +LG ++VP +P G P S + +G Sbjct: 4099 GQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT--QNLLGPQ 4156 Query: 2346 SKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQ---SDSPQSHRNAS 2402 E P TG P + G+G + Q + +PQ + Sbjct: 4157 QPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSP 4216 Query: 2403 HQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRH 2462 Q Q L Q Q+S+ ++ P E G G + C+ F GP Sbjct: 4217 QQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPL-QGLLGCQPQLGGF-PGPQTGPL 4274 Query: 2463 KARKHRPHP-GAPAEPSPAAL----PAQQPLEPLAQKCQP--PRKKSHRVS-GKERPNHS 2514 + P P G P P+P P P+ P P P++ S S + P + Sbjct: 4275 QELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEA 4334 Query: 2515 RGDPSH---------VTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTP 2560 + P+H +PPP + S + + S+ L P P ++ + + P Sbjct: 4335 QLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389 Score = 35.4 bits (80), Expect = 1.1 Identities = 94/387 (24%), Positives = 132/387 (34%), Gaps = 86/387 (22%) Query: 3223 SPGDPWGQEGEAKKDSPGERAKPRARSTPSNP---DGAATP---DSASATALADAGS--- 3273 SP P +E R P +P++P D A+P DS + L ++ Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728 Query: 3274 PGPPRTTP-------SPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCGKRFPKPFKLQR 3326 P P+ P SP P+ EP L P E P + H P+P + Sbjct: 729 PEEPQLCPRSEGPHLSPRPE-----EPHLSPRP-EEPHLSPQAEEPHLS---PQP---EE 776 Query: 3327 HLAVHSPQRVYLCPRC--PRVYPEHGELLAHLGGAHGLLERPELQHTPLYACELCATVMR 3384 P+ +L P+ P + P+ EL HL E P L P C + Sbjct: 777 PCLCAVPEEPHLSPQAEGPHLSPQPEEL--HLSPQ---TEEPHLSPVPEEPC-----LSP 826 Query: 3385 IIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGAPGQKARALEGTLPS 3444 ++S + H++ L + P + R + P PGQ E L Sbjct: 827 QPEESHLSPQSEEPCLSPRPEESHLSPELE--KPPLSPRPEKPPEEPGQCPAPEELPL-- 882 Query: 3445 KRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLER--P 3502 P PGE P P LSE P L L E+ P + G P + P Sbjct: 883 ----------FPPPGEPSLSPLLGEPALSEPGEPPLSPLPEEL-PLSPSGEPSLSPQLMP 931 Query: 3503 VDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERP---ENEASPGSP 3559 DP+ P L PP+LSP G LE P + ++ P SP Sbjct: 932 PDPLPPP-----LSPIITAAAPPALSPL--------------GELEYPFGAKGDSDPESP 972 Query: 3560 --GPLLQQALPLGASLPRPGARGQDAE 3584 P+L+ + P P A D E Sbjct: 973 LAAPILETPIS-----PPPEANCTDPE 994 Score = 34.7 bits (78), Expect = 1.9 Identities = 106/467 (22%), Positives = 149/467 (31%), Gaps = 113/467 (24%) Query: 1098 LTQGPREDEPQKPRKAARQEAGGDG---APANPEEPGGSRPGPGRSPQARGPSRSLETGA 1154 LT + EPQ P R + AP+ P P RPG P A+ P L Sbjct: 2331 LTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPP---LTPRP 2387 Query: 1155 AAREGGPKCADRPSVAPKDPL-QVPTNTETSEETR--------------PSLDFPQ-EAK 1198 CA P P DP +VP + ++ ++ PS P+ ++ Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSP 2447 Query: 1199 EPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLL----------------------- 1235 +P + S P S + L PP E+ G L Sbjct: 2448 DPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELH 2507 Query: 1236 --IPEQPPPSRHDT-------GTPKPSGSLANTA-----------------PHGSSPTPG 1269 +P PP+ + GTP P A PHG + G Sbjct: 2508 AKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFG 2567 Query: 1270 VGSLLGGPGGTQAPVS----HNSKDPPARQPGEF-----LAPVANPSSTACPKPSVLSSK 1320 G LG P T V+ H S P G L+P+ PS P P Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY 2627 Query: 1321 ISSFGCDPAGFNRDPLGVPVAKK---GPQPYSSPHSELFLGPKD-----LAGCFLEELHP 1372 +S +G PV K+ G SS + G +D L+ LE+ Sbjct: 2628 LSHGASQRSGITS-----PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQ 2682 Query: 1373 KPSARD---APPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEP----------GRAASP 1419 + R+ + L Q+ E A + + PPG+ EP G+ Sbjct: 2683 RQRLRELLIRQQIQRNTLRQEKETAAAAAGAV--GPPGSWGAEPSSPAFEQLSRGQTPFA 2740 Query: 1420 PTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPS 1466 T + SSL LP + P+ G S D L + PP PS Sbjct: 2741 GTQDKSSLV-GLPPSKLSGPILGPGSFPSDDRL----SRPPPPATPS 2782 Score = 33.9 bits (76), Expect = 3.3 Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 14/135 (10%) Query: 424 DTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLP 483 D+E AA GP + P T + P P G + S+ +G P + P+ Sbjct: 12 DSEPAADGPAASEDPSA---TESDLPNPHVGEV----SVLSSGSPRLQETPQDCSGGPVR 64 Query: 484 WPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK-LPAVRSSQG 542 + PS HG L R P P S G +PGP E LP+ SQ Sbjct: 65 RCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGG------SPGPNEAVLPSEDLSQI 118 Query: 543 GSPALFTYNGMTDPG 557 G P T + +PG Sbjct: 119 GFPEGLTPAHLGEPG 133 Score = 33.1 bits (74), Expect = 5.6 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 24/84 (28%) Query: 582 RVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHP 641 R + A P E P P P SP++ SPA+P +E PL PT P Sbjct: 4904 RQLSAPPPEEPSPPP------------SPLAPSPASPPTE------PL-----VELPTEP 4940 Query: 642 QETGSPFPSPEPPHSLPTHYQPEP 665 P PSP P S P +P+P Sbjct: 4941 L-AEPPVPSPLPLASSPESARPKP 4963 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 94.0 bits (232), Expect = 3e-18 Identities = 269/1192 (22%), Positives = 370/1192 (31%), Gaps = 240/1192 (20%) Query: 5 RPRGAPPPTMTGDLQPRQVASS------PGHPSQPPLEDNTPATRTTKGAREAGGQAQAM 58 +P G PP + L P+ A + G P P + P T A +AG Sbjct: 354 KPAGVLPPKLY-QLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLS 412 Query: 59 ELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTP---------------------- 96 P A QA + P + G AP PG P + Sbjct: 413 GFP-APALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQ 471 Query: 97 ---PGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTP 153 PG +Q P +L+ Q IL A+ T L P A + Sbjct: 472 FLLPGAPAVQLPQQLSALPANVGGQ--ILAAAAPHTGGQLIANPILTNQNLAGPLSLGPV 529 Query: 154 QGPGTGA---------PLRPGLPR--------------TEAQPAAEELGFHRCFQ----- 185 P +GA P++ G P T++QPA Q Sbjct: 530 LAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLP 589 Query: 186 --------------EPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPL--------QPGS 223 +P + +T +P T +P PP PL QP Sbjct: 590 PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649 Query: 224 YPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGA 283 P QA+ PP A P + PE I G P +P + Q Sbjct: 650 APTPQAAA----PPQATTPQPSPGLA---SSPEKIVLGQPPSATPTAILTQDSLQMFLPQ 702 Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAV------GTGPAYP-LPTQPAPSP-L 335 P G + V P P A G GP P PAP+P + Sbjct: 703 ERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQI 762 Query: 336 PCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTR 395 P G G SSP H AP DS H L P RPPS + Sbjct: 763 PAAAPLKG--------PGPSSSPSLPHQAP--LGDSPH--LPSPHPTRPPSRPPSRPQSV 810 Query: 396 GPPSSLPQRH----------FPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTA 445 P S P H PG + + P + APGPP L P Sbjct: 811 SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPE 870 Query: 446 APYPTPPGGPLAATRSMFFNGQ------PSPGQRLCLPQSAPLPWPQVLPTARPSPHGME 499 P P P P ++T S + P+P Q P P PT P+ H Sbjct: 871 GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLH--- 927 Query: 500 MLSRLPFPAGGPEWQGGSQGALGTAGKT-PGPREKLPA---------VRSSQGGSPAL-- 547 +P PA P + + T P P+ L +++ GG+PA Sbjct: 928 ---LVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQ 984 Query: 548 --FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPS--PATNTAGS 603 + +T P A L G A P GTP+ P A + + LP PA N A + Sbjct: 985 TSTSLGPLTSPAASVLVSGQA-----PSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFA 1039 Query: 604 ----TCSSLSPMSSSPANPSS--EESQLPG-----PLGPS--AFFHPPTHPQETG----- 645 T + SS P PS ES+L G L PS A F H + Sbjct: 1040 SNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPD 1099 Query: 646 --SPFPSPEPP--HSLPTH-YQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRG 700 + FPS E LP H YQ A P P+D + F+ + + + Sbjct: 1100 YKTAFPSFEDALHRLLPYHVYQG----ALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKY 1155 Query: 701 GLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARA 760 L + P+ + Q + +++ + GL +A + Sbjct: 1156 RLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAAS 1215 Query: 761 KDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSL 820 +GH+ P S P A P H T L+ A G SL Sbjct: 1216 SEGHRLPGHGPLSSSAPGASTQPPP-------HLPTKLVIRHGGAGGSPSVTWARASSSL 1268 Query: 821 AATPFPLPA-SDLDMEDDAKLDSLITEALNGMEYQS---------DNPEIDSSFIDVFAD 870 +++ A S LD ++D + S + E +S + + D Sbjct: 1269 SSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALD 1328 Query: 871 EEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLG 930 P P+ T + PPP P P P G P P+ + LG Sbjct: 1329 PVHQPPPPPA-----------TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLG 1377 Query: 931 LAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSG---GGGRA----------SG 977 AP P + K +R+++ GA EG+ +G GG A SG Sbjct: 1378 TAPHCPRLPLR----------KTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSG 1427 Query: 978 L---RPRRNDGLGER----PPPRPRRPRTQAPGSRADPAPRVPRAAALPEET 1022 L D L +R PPP P Q G AP +P A E+ Sbjct: 1428 LIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSES 1479 Score = 65.9 bits (159), Expect = 8e-10 Identities = 120/477 (25%), Positives = 159/477 (33%), Gaps = 104/477 (21%) Query: 1107 PQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAARE---GGPKC 1163 PQ P + G P + P P PQA P S ++ + G P Sbjct: 625 PQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPS 684 Query: 1164 ADRPSVAPKDPLQVPTNTETSEETR----PSLDFPQEA--KEPETAEESAPDSTEFTEAL 1217 A ++ +D LQ+ E S++ P L P P A++ AP +T + Sbjct: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAP-ATPVAKGA 743 Query: 1218 RSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGP 1277 P A + +P IP P P S SL + AP G SP L P Sbjct: 744 GLGPQAPDSQASPAPAPQIPAAAPLKGPG---PSSSPSLPHQAPLGDSPH------LPSP 794 Query: 1278 GGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSF------GCDPAGF 1331 T+ P PP+R P P + P CP P + F G P Sbjct: 795 HPTRPP-----SRPPSR-PQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPAS 848 Query: 1332 NRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDG 1391 N P A PQP P S+ GP P A PP+S+S Sbjct: 849 NP----APTAPGPPQPPLRPQSQPPEGPL-------------PPAPHLPPSSTSSAVASS 891 Query: 1392 EDAGSLEP---------QLPRS--------PPGTAETEPGRAASPP----TLES-SSLFP 1429 + S P Q P S PP T P AA PP T + ++ FP Sbjct: 892 SETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFP 951 Query: 1430 DLP-----VDRFDPPLYGSLSANRDSGLPFAC---------------------ADPPQKT 1463 LP ++RF G + N+ G P A A T Sbjct: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011 Query: 1464 VPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPSLPGKGSG 1520 PS P P+ + + P+LP+ K + P V AA S PGK SG Sbjct: 1012 APSHAPAPAPMAATGLPPLLPAE------NKAFASNLPTLN--VAKAASSGPGKPSG 1060 Score = 53.5 bits (127), Expect = 4e-06 Identities = 300/1364 (21%), Positives = 432/1364 (31%), Gaps = 283/1364 (20%) Query: 1119 GGDGAPANPE-----EPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKD 1173 GG GA + P +P PG G SP P+ L + P P + Sbjct: 308 GGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLT 367 Query: 1174 PLQ-VPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASP 1232 P P + + P PQ+ K P+ A L PA P Sbjct: 368 PKPFAPAGATLTIQGEPGA-LPQQPKAPQNLTFMAAGKAGQNVVLSGFPA---------P 417 Query: 1233 GLL--IPEQPPPSRHDTGTPKPSGSLANTAP-----HGSSPTPGVGSLLGG------PGG 1279 L + +QPP + P+P G+L+ GSS +L G PG Sbjct: 418 ALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA 477 Query: 1280 TQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVP 1339 + PA G+ LA A + +L+++ + AG PL + Sbjct: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQ------NLAG----PLSL- 526 Query: 1340 VAKKGP--QPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSL 1397 GP P+S HS L + +P+ P + + AGSL Sbjct: 527 ----GPVLAPHSGAHSAHILSAAPIQV-------GQPALFQMPVSLA---------AGSL 566 Query: 1398 EPQLPRSPPGTAETEPGRAAS-PPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFAC 1456 Q +P G A T + + PP+ + PD V P +A P Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATP------AAATGEAAPVLT 620 Query: 1457 ADPPQKTVPS-DPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPSLP 1515 P + P+ P P L L++ P P T P PG A S P Sbjct: 621 VQPAPQAPPAVSTPLP--LGLQQPQAQQPPQAPTPQAAAPPQATTPQPS---PGLASS-P 674 Query: 1516 GK---GSGCSVALMSHLSEDELEI--------QKLVTELESQLQRSKDTRGAPRELAEAE 1564 K G S + L++D L++ Q L E + AP + Sbjct: 675 EKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPA 734 Query: 1565 SVGRVELGTGTEPPSQRRTCQAT-VPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQ 1623 V G G P Q QA+ P +AA L G S++ ++ Sbjct: 735 PATPVAKGAGLGP--QAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQA--------- 783 Query: 1624 GRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAE 1683 P G P S HP P ++ VS P P H P +A + G+ + Sbjct: 784 --PLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPP---LHPCPPPQAPPTLPGIFVIQ 838 Query: 1684 GDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSF-----PKNKEAASSQESEDSLR 1738 P P P+ PGP P+ L P + +A + SE S R Sbjct: 839 NQLGVPPPASNPAPTA-PGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSR 897 Query: 1739 LLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLD-------A 1791 L P F + + PH+ P P +HL P+ A APP Sbjct: 898 L-PAPTPSDFQLQFPPSQGPHKSPTPP-----PTLHLVPEPA-----APPPPPPRTFQMV 946 Query: 1792 TWPFGASPSHAA--QGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVP 1849 T PF A P A + +G L AG APA + T+ L P Sbjct: 947 TTPFPALPQPKALLERFHQVPSGIILQNKAGG--------APAAPQTSTS-------LGP 991 Query: 1850 VPSPAC---VSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPR 1906 + SPA VS PS P+ +P P P A +L + A+ P Sbjct: 992 LTSPAASVLVSGQAPSGTPTAPSHAPA------PAPMAATGLPPLLPAENKAFASNLP-- 1043 Query: 1907 VNPSGLEGGTVEGGKVAC-GPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQ 1965 T+ K A GP G P G+Q + + L+ L K Q Sbjct: 1044 ---------TLNVAKAASSGP--GKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQ 1092 Query: 1966 G--------------QGTANQLQPEN---GVSPGGTDNH--------ASVNASPKTALTG 2000 G + ++L P + G P +D H S +T Sbjct: 1093 GSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAML 1152 Query: 2001 PTEGAVLLEKCKGSRAA--------MSLQEE----------AEPTPSPPSPNRESLALAL 2042 +LLE+ + + M +QEE A+ P + SL L + Sbjct: 1153 NKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPI 1212 Query: 2043 TAAHSRSGSEGRTPERASSPGLNK---PLLAT---------GDSPAPSVGDLAACAPSPT 2090 A+ G P +S+PG + P L T G SP+ + ++ S + Sbjct: 1213 AASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSS 1272 Query: 2091 SAAHMPCSL-----GPLP-REDPLTSPSRAQGGLGGQLPAS---------------PSCR 2129 S++ SL GP+P R P A+ +G +L P + Sbjct: 1273 SSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQ 1332 Query: 2130 DPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPS--LTTSPCDPKEALAGCLL 2187 PP P L P P T P AP L T+P P+ L Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR 1392 Query: 2188 QGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAG 2247 + G P P P G G +P ++ E ATS + Sbjct: 1393 ENVGGP-GAPEGTPAGRAR-------GGSPAPLPAKVDE-------------ATSGLIRE 1431 Query: 2248 AVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPP-----HTNPDRMPRGHSSYS 2302 + + L P A A +G PD ++ G PP +PD SS S Sbjct: 1432 LAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDS 1491 Query: 2303 PSNTARLGH-----------REGQAVTAVPTEPPTLQGAGPDSP 2335 P + H ++ T P+ P P SP Sbjct: 1492 PQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535 Score = 53.5 bits (127), Expect = 4e-06 Identities = 124/531 (23%), Positives = 175/531 (32%), Gaps = 105/531 (19%) Query: 3411 KHLRGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPG----------- 3459 +H+ G+ F PGAP + LP+ + +AP G Sbjct: 463 QHMLPGQNQFLL-----PGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTN 517 Query: 3460 EDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNH 3519 ++ P P+L+ S H+ S A G P + PV + LP+ Sbjct: 518 QNLAGPLSLGPVLAPHSGAHSAHILS--AAPIQVGQPALFQMPVS-----LAAGSLPTQS 570 Query: 3520 QECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGAR 3579 Q P PAA L G P A +P L+Q A P A+ Sbjct: 571 QPAPAG-----PAATT------VLQGVTLPPSAVAMLNTPDGLVQPATPAAAT------- 612 Query: 3580 GQDAEGKRAP-LVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFH 3638 G+ AP L +AP A P Q+ Q + + + P+ T Sbjct: 613 -----GEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQ---AAAPPQAT-- 662 Query: 3639 KGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGEL------ARGTENGMK 3692 +P+ +SS ++ P A + + ++ P E A G + Sbjct: 663 ---TPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719 Query: 3693 ---------------PATPKAK------PGPSSQGSGSPRPGTKTGGGSQ-PQPASGQLQ 3730 PATP AK P SQ S +P P + P P+S Sbjct: 720 ASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779 Query: 3731 SETATTPAKPSFPSRSPA--PERLPARAQAKSCTKGPREAG-EQGPHGSLGPKEKGESST 3787 A P PS P P R P+R Q S ++ P E P P G Sbjct: 780 PHQAPLGDSPHLPSPHPTRPPSRPPSRPQ--SVSRPPSEPPLHPCPPPQAPPTLPGIFVI 837 Query: 3788 KRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPS 3847 + + G VP PA + AP+AP P R Q+ P P P P + P PPS Sbjct: 838 QNQLG-VPPPASNP-------APTAPGPPQPPLRPQSQP----PEGPLPPA---PHLPPS 882 Query: 3848 EQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAE 3898 A ++ RL P L PP +G H + P H E Sbjct: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGP--HKSPTPPPTLHLVPE 931 Score = 50.8 bits (120), Expect = 3e-05 Identities = 237/1085 (21%), Positives = 345/1085 (31%), Gaps = 228/1085 (21%) Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGA 1154 E EL GP + +P G GA A P PG T Sbjct: 121 EAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPG--------------STDL 166 Query: 1155 AAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214 +G P ++ P P V + + + +P + P+ Sbjct: 167 LGLQGPPTVLTHQALVP--PQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNG---- 220 Query: 1215 EALRSPPAACAGEMGASP---------------GLLIPEQPPPSRHDTGTPKPSGSL--- 1256 SP A A +G +P L+ +Q P S + PS + Sbjct: 221 ----SPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLA 276 Query: 1257 -ANTAPHGS------------SPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPV 1303 A +P G+ + T S+ GG G AP S P A PG +P+ Sbjct: 277 SAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPL 336 Query: 1304 ANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLA 1363 P P+V+ + P P GV L PK Sbjct: 337 V-------PAPNVILHR------TPTPIQPKPAGV------------------LPPK--- 362 Query: 1364 GCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLE 1423 L +L PKP A PA ++ Q + G+L PQ P++P G+A L Sbjct: 363 ---LYQLTPKPFA----PAGATLTIQG--EPGAL-PQQPKAPQNLTFMAAGKAGQNVVL- 411 Query: 1424 SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPML 1483 S P L + F P + A PPQ P LL + S ++ Sbjct: 412 SGFPAPALQANVFKQPPATTTG-----------AAPPQPPGALSKPMSVHLLNQGSSIVI 460 Query: 1484 PSHFPDLSGGKVLSKTCPPERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTEL 1543 P+ + L P + +P +LP G +A + + +L ++T Sbjct: 461 PAQHMLPGQNQFLLPGAPAVQ--LPQQLSALPANVGGQILAAAAPHTGGQLIANPILTN- 517 Query: 1544 ESQLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLT--- 1600 + LA S+G V PH SA L+ Sbjct: 518 --------------QNLAGPLSLGPV-----------------LAPHSGAHSAHILSAAP 546 Query: 1601 -RVGESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSG----A 1655 +VG+ + A ++ Q +P P + G L P A L + Sbjct: 547 IQVGQPALFQMPVSLAAGSL-PTQSQPAPAGPAATTVLQG-VTLPPSAVAMLNTPDGLVQ 604 Query: 1656 PFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSP 1715 P +P A PV + QA P + L +P Q PQ A +P Sbjct: 605 PATPAAATGEAAPVLTVQPAP----QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAA--AP 658 Query: 1716 DQELSFPKNKEAASSQE----------------SEDSLRLLPCEQRGGFLPEPGTADQPH 1759 Q + + ASS E ++DSL++ ++R +P +A+ PH Sbjct: 659 PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERS---QQPLSAEGPH 715 Query: 1760 RGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFG-ASPSHAAQGHSAGRAGGHLHPT 1818 PA +P P A L P ASP+ A Q +A G Sbjct: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG----- 770 Query: 1819 AGRPGFEGNEFAPAGASSL--TAPRGREAWLVPVPSPACVSNTHPSRRS--QDPALSPPI 1874 PG P+ + SL AP G L P P P + PSR P PP+ Sbjct: 771 ---PG-------PSSSPSLPHQAPLGDSPHL-PSPHPTRPPSRPPSRPQSVSRPPSEPPL 819 Query: 1875 RQLQLPGPGVAKSKDGILGLQE---LTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSP 1931 P P + GI +Q + P A +P P + + GP +P Sbjct: 820 H--PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAP 877 Query: 1932 GGVQVTTLPAVAGH---QLGLEADGHWGLLGQAEKTQGQGTAN------QLQPENGVSPG 1982 +T AVA L A Q +QG + L PE P Sbjct: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPP 937 Query: 1983 GTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPP------SPNRE 2036 + +P AL P LLE+ + + LQ +A P+ P P Sbjct: 938 PPPRTFQMVTTPFPALPQP---KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS 994 Query: 2037 SLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMP 2096 A L + + SG+ P A +P P+ ATG P + A + PT Sbjct: 995 PAASVLVSGQAPSGTP-TAPSHAPAPA---PMAATGLPPLLPAENKAFASNLPTLNVAKA 1050 Query: 2097 CSLGP 2101 S GP Sbjct: 1051 ASSGP 1055 Score = 49.3 bits (116), Expect = 8e-05 Identities = 92/359 (25%), Positives = 124/359 (34%), Gaps = 54/359 (15%) Query: 78 LRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLA---GRAEGSPPQRYILGIASSRTKPTLD 134 L G P S+ S Q PP P++L G A GSP + ASS + Sbjct: 1221 LPGHGPLSSSAPGASTQPPP-----HLPTKLVIRHGGAGGSPSVTWAR--ASSSLSSSSS 1273 Query: 135 ETPENPQLEAAQ---LPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRC----FQEP 187 + L+A + +P + P A R GL Q A H +P Sbjct: 1274 SSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQP 1333 Query: 188 PSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASG-ADSWPPAAENSFPGA 246 P + P P PP P Q GT P + PE + G A P Sbjct: 1334 PPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRE 1393 Query: 247 NFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAF 306 N G P A PE P G GGSP P PA +T ++A + Sbjct: 1394 NVGGPGA-PEGTPAGRARGGSPA------PLPAKVDEATSGLIRELAA-------VEDEL 1439 Query: 307 HQP--QGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSA 364 +Q +G PE A P AP G P R S+ + A+ S+ Sbjct: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAP-------GLPPAKRRKSE---SPDVDQASFSS 1489 Query: 365 PRPFSDSLHKSLTKIL---------PERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRAS 414 P D+L + L + P R P+ ++ G P+S P H P +AY S Sbjct: 1490 DSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRP-EAYPPS 1547 Score = 47.8 bits (112), Expect = 2e-04 Identities = 203/930 (21%), Positives = 289/930 (31%), Gaps = 181/930 (19%) Query: 522 GTAGKTPGPREKLPAVRSSQGGSP---ALFTYNGMTDPGAQPL----FFGVAQPQVSPHG 574 G GP E P +S G SP L ++ A L FG A +P G Sbjct: 261 GYLASAAGPSE--PVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTG 318 Query: 575 TPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634 TPS P V S +P+P + +P+ PA G L P + Sbjct: 319 TPSGQPLAVAPGLGSSPLVPAPNVILHRTP----TPIQPKPA----------GVLPPKLY 364 Query: 635 FHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEG 694 P G+ P +LP QP+ + F A G + L P P Sbjct: 365 QLTPKPFAPAGATLTIQGEPGALPQ--QPKAPQNLTFMAAGKAGQNVV--LSGFPAPALQ 420 Query: 695 PEVGRGGLQGFPRAPPPYPT-----------------------------HHFSLSSASLD 725 V + A PP P + F L A Sbjct: 421 ANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAV 480 Query: 726 QLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPAD 785 QL L+ + LAA H G L+A +Q GP L P AP Sbjct: 481 QLPQQLSALPANVGGQILAAAAPHTG--GQLIANPILTNQNLAGPLSL-GPVLAP----- 532 Query: 786 AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDD-AKLDSLI 844 H+G +H+ L A P++ G P+L P L A L + A Sbjct: 533 -HSG--AHSAHILSAA---------PIQVG-QPALFQMPVSLAAGSLPTQSQPAPAGPAA 579 Query: 845 TEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPP----P 900 T L G+ + ++ + P+ G ++ P+ + V P +APP P Sbjct: 580 TTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAA--PVLT---VQPAPQAPPAVSTP 634 Query: 901 LPAATPDPQTPRPGDRGCP-ARGRPKTRSLGLAPTEADAPSQ---GRQQRRGKQLKLFRK 956 LP PQ +P P A P+ + +P A +P + G+ L + Sbjct: 635 LPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQD 694 Query: 957 DLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRT----------QAPGSRA 1006 L E S L + + PP + P T QAP S+A Sbjct: 695 SLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQA 754 Query: 1007 D--PAPRVPRAA-----------ALPEETRSSRRRRLP---PRKDPRKRKARGGAWGKEL 1050 PAP++P AA +LP + LP P + P + +R + + Sbjct: 755 SPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRP- 813 Query: 1051 ILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKP 1110 SE PPP+ P P P Sbjct: 814 ----------------PSEPPLHPCPPPQAP-------------------------PTLP 832 Query: 1111 RKAARQEAGGDGAPA-NPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSV 1169 Q G PA NP P P PQ++ P L A S Sbjct: 833 GIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSS 892 Query: 1170 APKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMG 1229 L PT ++ + PS P ++ P P+ A PP +M Sbjct: 893 ETSSRLPAPTPSDFQLQFPPS-QGPHKSPTPPPTLHLVPE-----PAAPPPPPPRTFQMV 946 Query: 1230 ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSK 1289 +P +P+ P + + PSG + G+ P + LG A V + + Sbjct: 947 TTPFPALPQ--PKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQ 1004 Query: 1290 DPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGP---- 1345 P AP P + A P +L ++ +F + N A GP Sbjct: 1005 APSGTPTAPSHAPAPAPMA-ATGLPPLLPAENKAFASNLPTLN----VAKAASSGPGKPS 1059 Query: 1346 -QPYSSPHSELFLGP---KDLAGCFLEELH 1371 Y S S L P CFLE LH Sbjct: 1060 GLQYESKLSGLKKPPTLQPSKEACFLEHLH 1089 Score = 47.4 bits (111), Expect = 3e-04 Identities = 186/843 (22%), Positives = 266/843 (31%), Gaps = 149/843 (17%) Query: 1757 QPHRGAPAPE-AFGSPAVHLAPDLAFQGDG------APPLDATWPFGASPSHAAQG---- 1805 QP G P A G+ AV P F G PP T P Sbjct: 135 QPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSV 194 Query: 1806 ----HSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHP 1861 G L P G G +P GA++ T A + V P NT Sbjct: 195 QPFLQPVGLGNVTLQPIPGLQGLPNG--SPGGATAATLGL---APIQVVGQPVMALNTPT 249 Query: 1862 SR--RSQDP------ALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLE 1913 S+ Q P + + P + L GV+ G++ + L+ A + L Sbjct: 250 SQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATT-------LN 302 Query: 1914 GGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQL 1973 G +V GG A G+P G + P + L A T + Sbjct: 303 GNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLV-----------PAPNVILHRTPTPI 351 Query: 1974 QPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSP 2033 QP+ P G +PK + A +L + EP P P Sbjct: 352 QPK----PAGVLPPKLYQLTPKPF----------------APAGATLTIQGEPGALPQQP 391 Query: 2034 NRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAA 2093 + A G+ + G P L P A P P A Sbjct: 392 KAPQNLTFMAA--------GKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGAL 443 Query: 2094 HMPCSLGPLPREDPLTSPSRAQGGLGGQ----LPASPSCRDPPGPQQLLACSPAWAPLEE 2149 P S+ L + + P AQ L GQ LP +P+ + P QQL A P Sbjct: 444 SKPMSVHLLNQGSSIVIP--AQHMLPGQNQFLLPGAPAVQLP---QQLSAL-----PANV 493 Query: 2150 ADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSA-V 2208 + A +A P LT + LAG L G P+ P S G+ SA + Sbjct: 494 GGQILAAAAPHTGGQLIANPILTN------QNLAGPLSLG---PVLAPHS---GAHSAHI 541 Query: 2209 TCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAV--RATGLSSTPTG 2266 + + ++P L A + P A V V + A + +TP G Sbjct: 542 LSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDG 601 Query: 2267 ------DEAQAGRGLP----GPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQA 2316 A G P P PQ APP + S LG ++ QA Sbjct: 602 LVQPATPAAATGEAAPVLTVQPAPQ---APP--------------AVSTPLPLGLQQPQA 644 Query: 2317 VTAVPTEPPTLQGAGPDSPACLEGEMG-TSSKEPEDPGTPETGRSGATKMPRVTCPSTGL 2375 P + PT Q A P + G SS E G P + AT +T S + Sbjct: 645 QQ--PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPS----ATPTAILTQDSLQM 698 Query: 2376 GLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQW 2435 L + + +++ S + S P DP + ++G P + ++ Sbjct: 699 FLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV---AKGAGLGPQAPDSQAS 755 Query: 2436 KGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP-------AQQPL 2488 AP P + S P L PH +P P + P ++ P Sbjct: 756 PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815 Query: 2489 EPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP-PPAQGSKEVLRAPGSPHSQQLHP 2547 EP C PP+ + G + G P + P P A G + P S + P Sbjct: 816 EPPLHPCPPPQAPP-TLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLP 874 Query: 2548 PSP 2550 P+P Sbjct: 875 PAP 877 Score = 47.4 bits (111), Expect = 3e-04 Identities = 98/414 (23%), Positives = 135/414 (32%), Gaps = 47/414 (11%) Query: 2025 EPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAA 2084 +P P P L L L ++ + TP+ A+ P P + G + +P L Sbjct: 622 QPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQ 681 Query: 2085 CAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAW 2144 + +A SL ++ P A+G +PAS PP Q +P Sbjct: 682 PPSATPTAILTQDSLQMFLPQERSQQPLSAEGP-HLSVPASVIVSAPPPAQDPAPATP-- 738 Query: 2145 APLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPS---SWP 2201 GA P AP S SP + A L+G G P PS P Sbjct: 739 ------------VAKGAGLGPQAPDS-QASPAPAPQIPAAAPLKGPG-PSSSPSLPHQAP 784 Query: 2202 PGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLS 2261 G + H P R SR E P PP A P + V L Sbjct: 785 LGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS--EPPLHPCPPPQAPPTLPGIFVIQNQLG 842 Query: 2262 -STPTGDEAQAGRGLPGPDPQSRGAP--------PHTNPDRMPRGHSSYSPSNTA----- 2307 P + A G P P + + P PH P +S S +++ Sbjct: 843 VPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPT 902 Query: 2308 ----RLGHREGQAVTAVPTEPPTL----QGAGPDSPACLEGEMGTSSKEPEDPGTPETGR 2359 +L Q PT PPTL + A P P +M T + P P P+ Sbjct: 903 PSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVT-TPFPALP-QPKALL 960 Query: 2360 SGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGP 2413 ++P G G AP ++ S SP + S Q P G P P Sbjct: 961 ERFHQVPSGIILQNKAG-GAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAP 1013 Score = 47.4 bits (111), Expect = 3e-04 Identities = 103/422 (24%), Positives = 143/422 (33%), Gaps = 112/422 (26%) Query: 3424 GVRRPGA--PGQKARALEGTLPSKRRRVAMPGSAPGPGE---DRPPPRGSSPILSEGSLP 3478 G+++P A P Q P PG A P + +PP + IL++ SL Sbjct: 638 GLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQ 697 Query: 3479 ALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA-LADG 3537 L P + +G L P + PPP+ P PA +A G Sbjct: 698 MFLPQERSQQPLSAEG--PHLSVPASVIV-------------SAPPPAQDPAPATPVAKG 742 Query: 3538 RGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRR 3597 G + P+++ASP +P P +P A L PG + +APL S Sbjct: 743 AGL-----GPQAPDSQASP-APAP----QIPAAAPLKGPGPSSSPSLPHQAPLGDS---- 788 Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSA 3657 H H T+P + S+ +S Sbjct: 789 ----------PHLPSPH---------------------------PTRPPS-RPPSRPQSV 810 Query: 3658 ASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSP--RPGTK 3715 + PS+ P P +A +L PG + G+ P P + P P++ G P RP Sbjct: 811 SRPPSEPPLHPCPPPQAPPTL-PGIFVIQNQLGVPP--PASNPAPTAPGPPQPPLRP--- 864 Query: 3716 TGGGSQPQPASGQLQSETATTPAKPS--FPSRSPAPERLPARAQAKSCTKGPREAGEQGP 3773 Q QP G L P+ S S S RLPA + + P QGP Sbjct: 865 -----QSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPS---QGP 916 Query: 3774 HGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTK 3833 H S P VP PA + P PPRT + TP LP + Sbjct: 917 HKSPTPPPTLHL--------VPEPA------------APPPPPPRTFQMVTTPFPALP-Q 955 Query: 3834 PK 3835 PK Sbjct: 956 PK 957 Score = 46.6 bits (109), Expect = 5e-04 Identities = 81/363 (22%), Positives = 124/363 (34%), Gaps = 50/363 (13%) Query: 1091 EKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL 1150 E+ ++ +GP P +A A D APA P G GP P+ + Sbjct: 703 ERSQQPLSAEGPHLSVPASVIVSAPPPAQ-DPAPATPVAKGAGL-GPQAPDSQASPAPAP 760 Query: 1151 ETGAAAREGGPKCADRPSVAPKDPL----QVPTNTETSEETRPSLDFPQEAKEPETAEES 1206 + AAA GP + PS+ + PL +P+ T +RP PQ P + Sbjct: 761 QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPP-SRPQSVSRPPSEPPL 819 Query: 1207 APDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSP 1266 P ++PP PG+ + ++ G P P+ + A TAP P Sbjct: 820 HP-----CPPPQAPPTL--------PGIFV------IQNQLGVPPPASNPAPTAP--GPP 858 Query: 1267 TPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGC 1326 P + P G P H P + VA+ S T+ P+ S Sbjct: 859 QPPLRPQSQPPEGPLPPAPH-------LPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP 911 Query: 1327 DPAGFNRDPLGVPVAKKGPQPYSSPHS-----ELFLGP---KDLAGCFLEELHPKPS--- 1375 G ++ P P P+P + P ++ P LE H PS Sbjct: 912 PSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGII 971 Query: 1376 ----ARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDL 1431 A AP A + + + + P T P A +P + ++ L P L Sbjct: 972 LQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLL 1031 Query: 1432 PVD 1434 P + Sbjct: 1032 PAE 1034 Score = 45.8 bits (107), Expect = 8e-04 Identities = 90/419 (21%), Positives = 137/419 (32%), Gaps = 68/419 (16%) Query: 3453 GSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRG 3512 GS P + P ++ +L +LP S VA T P+ L +P P Sbjct: 564 GSLPTQSQPAPAGPAATTVLQGVTLPP-----SAVAMLNT---PDGLVQPATPAAATGEA 615 Query: 3513 CELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGAS 3572 P L+ PA A L L++P+ + P +P P Q A P A+ Sbjct: 616 A-----------PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTP--QAAAPPQAT 662 Query: 3573 LPRPG----------ARGQDAEGKRAPLVFSGKRRA--PGARGRCAPDHFQEDHL-LQKE 3619 P+P GQ ++ + P R + P + HL + Sbjct: 663 TPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ-QPLSAEGPHLSVPAS 721 Query: 3620 KEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA 3679 VS+ + P KG+ P S + A P+ A P K G + Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA------PLKGPGPSS 775 Query: 3680 PGELARGTENGMKPATPKAKPG-----PSSQGSGSPRPGTKTGGGSQPQPASGQ------ 3728 L G P P P P S+ RP ++ P P + Sbjct: 776 SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835 Query: 3729 -LQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESST 3787 +Q++ P + +P P + P R Q++ P PH +S+ Sbjct: 836 VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQP----PEGPLPPAPHLPPSSTSSAVASS 891 Query: 3788 KRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPP 3846 ++P P S+ F P + P K TP L P+P + P PPP Sbjct: 892 SETSSRLPAPTPSDFQLQF--------PPSQGPHKSPTPPPTLHLVPEPAA---PPPPP 939 Score = 42.4 bits (98), Expect = 0.009 Identities = 150/659 (22%), Positives = 204/659 (30%), Gaps = 150/659 (22%) Query: 331 APSPLPCYQGQPGGLNRHSDLSGALSSPGAA-HSAPRPFSDSLHKSLTKILPERPPSAQD 389 A +P GQP + S + +P H P P L L + P Sbjct: 313 ASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFA 372 Query: 390 GLGST---RGPPSSLPQRHFPGQ--AYRASG-----VDTSPGP-PDTELAAPGPPPARLP 438 G+T +G P +LPQ+ Q + A+G V S P P + PPA Sbjct: 373 PAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATT- 431 Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWP-QVLPTARPSPHG 497 T A P PPG L+ S+ Q G + +P LP Q L P+ Sbjct: 432 -----TGAAPPQPPGA-LSKPMSVHLLNQ---GSSIVIPAQHMLPGQNQFLLPGAPAVQL 482 Query: 498 MEMLSRLPFPAGGPEWQGGSQGALGTAGKTP--------GPREKLPAVRSSQG------- 542 + LS LP GG + G P GP P + G Sbjct: 483 PQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHIL 542 Query: 543 -------GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLP-------PPRVVGASP 588 G PALF G+ P Q Q +P G + PP V Sbjct: 543 SAAPIQVGQPALFQMPVSLAAGSLP-----TQSQPAPAGPAATTVLQGVTLPPSAVAMLN 597 Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPF 648 + L PAT A +T + ++ PA + P PLG P Q +P Sbjct: 598 TPDGLVQPAT-PAAATGEAAPVLTVQPAPQAPPAVSTPLPLG----LQQPQAQQPPQAPT 652 Query: 649 PSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRA 708 P P P P P+ GL + L + P + + LQ F Sbjct: 653 PQAAAP----------PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMF--- 699 Query: 709 PPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSP 768 L Q +R+ L+A H ++ A Sbjct: 700 ---------------LPQ----------ERSQQPLSAEGPHLSVPASVIVSA-------- 726 Query: 769 GPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLP 828 PP P+ AP P AGL A D+QA P +P+ A P P Sbjct: 727 -PP--PAQDPAPATPVAKGAGLGPQAP------DSQASPAPAPQ----IPAAAPLKGPGP 773 Query: 829 ASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSK 888 +S + A L D+P + S PS P+ S P + Sbjct: 774 SSSPSLPHQAPL--------------GDSPHLPSPHPTRPPSRPPSRPQSVSRP-PSEPP 818 Query: 889 AGVTPESKAPP--------------PLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAP 933 P +APP P PA+ P P P P + +P L AP Sbjct: 819 LHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAP 877 Score = 38.9 bits (89), Expect = 0.10 Identities = 88/381 (23%), Positives = 123/381 (32%), Gaps = 71/381 (18%) Query: 958 LDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPR-PRRPRTQAPGSRADPAPRVPRAA 1016 L ++EG G G S P G +PPP P + + G+ P+ RA+ Sbjct: 1210 LPIAASSEGHRLPGHGPLSSSAP----GASTQPPPHLPTKLVIRHGGAGGSPSVTWARAS 1265 Query: 1017 ALPEETRSSRR---------------RRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061 + + SS R PP K R G L LKI Q+ Sbjct: 1266 SSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIG------LKLKIKQEAGLS 1319 Query: 1062 REYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGD 1121 + + + PPP +++ + P P P Sbjct: 1320 KVVHNTALDPVHQPPPPPAT--------------LKVAEPPPRPPPPPPPTGQMNGTVDH 1365 Query: 1122 GAPANPE-EPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTN 1180 PA PE +P G+ P R P R R G A EG P A R PL + Sbjct: 1366 PPPAAPERKPLGTAPHCPRLP-LRKTYRENVGGPGAPEGTP--AGRARGGSPAPLPAKVD 1422 Query: 1181 TETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPP---AACAGEMGASPGLLIP 1237 TS R E +A + + L+ PP AA A + P P Sbjct: 1423 EATSGLIR---------------ELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAP 1467 Query: 1238 EQPPPSRHDTGTPK-PSGSLANTAP-------HGSSPTPGVGSLLGGPGGTQAP-VSHNS 1288 PP R + +P S ++ +P H S + +L PG T AP H + Sbjct: 1468 GLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAA 1527 Query: 1289 KDPPARQPGEFLAPVANPSST 1309 P P A P S+ Sbjct: 1528 SAGTPASPPPLHRPEAYPPSS 1548 Score = 38.1 bits (87), Expect = 0.17 Identities = 44/146 (30%), Positives = 53/146 (36%), Gaps = 14/146 (9%) Query: 3693 PATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSP----- 3747 PAT K P P G G P PA+ + + T P P P R Sbjct: 1337 PATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE-RKPLGTAPHCPRLPLRKTYRENV 1395 Query: 3748 ----APERLPA-RAQAKSCTKGPREAGE--QGPHGSLGPKEKGESSTKRKKGQVPGPARS 3800 APE PA RA+ S P + E G L E E + KG P PA S Sbjct: 1396 GGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVED-ELYQRMLKGPPPEPAAS 1454 Query: 3801 ESVGSFGRAPSAPDKPPRTPRKQATP 3826 + G+ AP PP RK +P Sbjct: 1455 AAQGTGDPDWEAPGLPPAKRRKSESP 1480 Score = 37.4 bits (85), Expect = 0.30 Identities = 51/213 (23%), Positives = 71/213 (33%), Gaps = 37/213 (17%) Query: 1070 SEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPR----KAARQEAGGDGAP- 1124 +E +PPP P G + + P P PR K R+ GG GAP Sbjct: 1343 AEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPE 1402 Query: 1125 ---ANPEEPGGSRPGPGRSPQA--------------------RGPSRSLETGAAAREGGP 1161 A G P P + +A +GP AA G P Sbjct: 1403 GTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462 Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEF------TE 1215 + P + P + + + ++ S D PQ+ E + + T Sbjct: 1463 DW-EAPGLPPAKRRK--SESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTP 1519 Query: 1216 ALRSPPAACAGEMGASPGLLIPEQPPPSRHDTG 1248 A P AA AG + P L PE PPS H+ G Sbjct: 1520 APSYPHAASAGTPASPPPLHRPEAYPPSSHNGG 1552 Score = 33.9 bits (76), Expect = 3.3 Identities = 81/342 (23%), Positives = 109/342 (31%), Gaps = 62/342 (18%) Query: 333 SPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLG 392 SP + L+ S S A SS A P P + RPP Sbjct: 1256 SPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRN------------RPPIKTYEAR 1303 Query: 393 STRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPP 452 S G + Q + + +D PP PPPA L P P P PP Sbjct: 1304 SRIGLKLKIKQEAGLSKVVHNTALDPVHQPP--------PPPATLKVAEPPPRPPPPPPP 1355 Query: 453 GGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPE 512 G + T P P P+ PL +PH RLP E Sbjct: 1356 TGQMNGTVD-----HPPPAA----PERKPLG---------TAPH----CPRLPLRKTYRE 1393 Query: 513 WQGGSQGALGT-AGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVA-QPQV 570 GG GT AG+ G + + S + + D Q + G +P Sbjct: 1394 NVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAA 1453 Query: 571 SP-HGT-------PSLPPPRVVGASPSESPLPSPATNTAGSTCS-SLSPMSSSPANPSSE 621 S GT P LPP + SESP A+ ++ S +L+ S + Sbjct: 1454 SAAQGTGDPDWEAPGLPPAK---RRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILN 1510 Query: 622 ESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQP 663 Q PG P++P + P+ PP P Y P Sbjct: 1511 LQQAPGRTPA------PSYPHAASAGTPASPPPLHRPEAYPP 1546 Score = 32.3 bits (72), Expect = 9.5 Identities = 41/156 (26%), Positives = 51/156 (32%), Gaps = 49/156 (31%) Query: 2746 PAEDSSRAHSRSEEGVWEENTPPLGP-------------------LGFPETSSSPADSTT 2786 P SR SR + + PPL P LG P +S+PA + Sbjct: 796 PTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAP 855 Query: 2787 SSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRN 2846 P P + Q PEGP P A PPS V+ S T R Sbjct: 856 G------PPQPPLRPQSQPPEGPLPPAPHL----PPSSTSSAVASSSE-------TSSR- 897 Query: 2847 PHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARLPT 2882 LP PT F+ P+ GP + PT Sbjct: 898 ------------LPAPTPSDFQLQFPPSQGPHKSPT 921 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 93.6 bits (231), Expect = 3e-18 Identities = 257/1053 (24%), Positives = 331/1053 (31%), Gaps = 188/1053 (17%) Query: 1 MPG-ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED--NTPATRTTKGAREAGGQAQA 57 +PG + P+G P T Q + PG P P L P + G + + G Sbjct: 462 IPGVDGPKGEPGLLCT---QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518 Query: 58 MELPEAQPRQARDGELKPPSLRGQA-----PSSTPGKRGSP--QTPPGRSPLQAPSRLAG 110 LP G+ P L+G+ P G G P + PGR L G Sbjct: 519 TGLPGFPGFPGAQGD---PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575 Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGP-GTGAPLRPGLPRT 169 +G P + L ++ + P +P P P GP G G PGL T Sbjct: 576 -VKGLPGPKGELALSGEKGDQGPPGDPGSPGS-----PGPAGPAGPPGYGPQGEPGLQGT 629 Query: 170 EAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQ--PGSYPEY 227 + P A PP S S TP P PGPP G Q PG Sbjct: 630 QGVPGAPG---------PPGEAGPRGELSVS-TPVPGPPGPPGPPGHPGPQGPPGIPGSL 679 Query: 228 QASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSR--PGGSPR-GVSFQFPFPALHGA 283 G P P E PG F PP PKG + PG G + P L G Sbjct: 680 GKCGDPGLPGPDGEPGIPGIGFPGPPG-----PKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQP 342 P A GP F +G E P P LP P L +G P Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 343 GGLNRHSDLSGALSSPGAAHSAPR-----PFSDSLH-------KSLTKILPERPPSAQDG 390 G G PG PR P + L K+ K P P + G Sbjct: 795 G----QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850 Query: 391 LGSTRGPPS---------SLPQRHFPGQA--------------YRASGVDTSPGPPDT-- 425 G P L QR +PG G PGPP Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910 Query: 426 ---ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPL 482 + +PG P + Q P A G P + S + PG L A Sbjct: 911 TPGQRGSPGIPGVK-GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG----LKGFAGN 965 Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK--------- 533 P + P G++ L LP PAG P G +G LG+ G P + Sbjct: 966 PGEKG-NRGVPGMPGLKGLKGLPGPAGPP----GPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 534 -LPAVRSSQG--------GSPALFTYNGMTDPGAQPLFFGVAQP-QVSPHGTPSLPPPRV 583 +P + +G G P L +G+ +P + +P P G P LP Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSS-PANPSSEESQ----LPGPLGPSAFFHPP 638 + P P AG + SP S P P + G LGP PP Sbjct: 1081 KKGEMGQ-PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 639 THPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVG 698 P GSP P + P PA G +G L P P P G Sbjct: 1140 GLPGFPGSPGPMGIRGD--------QGRDGIPGPA---GEKGETGLLRAPPGPRGNP--G 1186 Query: 699 RGGLQGFPRAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLL 756 G +G AP P P ++ A R + + F G + Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAG-------------PRGPTGIEGFPGPPGLPGAI 1233 Query: 757 LA-----RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811 + R G + SPG PG P PP + + G + H G A G Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871 L P L P P D + G++ + NP F+ Sbjct: 1294 LGAPGTPGL-----PGPRGDPGF-----------QGFPGVKGEKGNP----GFLGSIGPP 1333 Query: 872 EPSGPRGPSS--GHPLKSKAGVTPESKAPPPLPA-----ATPDPQTPRPGDRG-CPARGR 923 P GP+GP G P K P S PP P P P P PG+ G C RG+ Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP-PGNLGPCGPRGK 1392 Query: 924 PKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRK 956 P G T A +G + +G+ LF + Sbjct: 1393 PGKD--GKPGTPGPAGEKGNKGSKGEPESLFHQ 1423 Score = 86.7 bits (213), Expect = 4e-16 Identities = 353/1494 (23%), Positives = 441/1494 (29%), Gaps = 412/1494 (27%) Query: 184 FQEPPSSFTSTNYTSPSATPRPPAP----------GPPQSRGTS-----------PLQPG 222 F PP S +T P P P P G RG S P PG Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPG 112 Query: 223 SYPEYQASGADSWPPA-AENSFPG--ANFGVP--------------PAEPEPIPKGSR-- 263 + Y G + E FPG G P PA+ E I ++ Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172 Query: 264 PG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG-- 319 PG G+P P P G P P G GP P+G E +G Sbjct: 173 PGLPGAPGPQGLPGP-PGFPGPVGPPGPPGFFGFPGAMGP-----RGPKGHMGERVIGHK 226 Query: 320 --------TGPAYP----LPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAP 365 TGP P + T P +G+ G G G PG ++ + Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286 Query: 366 R--PFSDSLHKSLTKI-LPERPPSAQDGLGSTRGPPSSLPQRHFPGQ------------- 409 + P L K +P P S +G+ RG P + + GQ Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGS--EGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344 Query: 410 ----AYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP-YPTPPGGPLAATR---- 460 Y+ G + +PGP PGP AR PQ P+ P P PG R Sbjct: 345 EYYDTYQEKGDEGTPGP-------PGPRGARGPQ--GPSGPPGVPGSPGSSRPGLRGAPG 395 Query: 461 ------SMFFNGQP------SPGQRLC-----LPQSAPLPWPQ---VLPTARPSPHGME- 499 S G+P +PG C LP S P P V P HG+ Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455 Query: 500 -------------------MLSRLPFPAGGPEWQG-----------GSQGALGTAGKTPG 529 + ++ P+ G P G G QGA G G Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515 Query: 530 P-REKLPAVRSSQG--GSPALFTYNGMT-----------DPG--AQPLFFGVAQPQVSPH 573 P LP G G P L G T DPG QP G+ +P Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP- 574 Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPS 632 G LP P+ A E P G S SP + PA P Q PG G Sbjct: 575 GVKGLPGPKGELALSGEKGDQGP----PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630 Query: 633 AFFHPPTHPQETG--------SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQC 684 P P E G +P P P P P H P+ P G G Sbjct: 631 GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---- 686 Query: 685 LEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLA 744 P E G G+ GFP P P F + SL Sbjct: 687 -----LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG------------------- 721 Query: 745 AFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQ 804 K G PG PGLP P V G T G+ Sbjct: 722 -------------CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG------TPGFPGERG 762 Query: 805 AEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSF 864 G+ + LP L TP E L+G P Sbjct: 763 NSGEHGEIGLPGLPGLPGTPG-------------------NEGLDGPRGDPGQP------ 797 Query: 865 IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924 P G +GP G ++ G ++ P L Q R G G +G P Sbjct: 798 -------GPPGEQGP-PGRCIEGPRG----AQGLPGLNGL--KGQQGRRGKTG--PKGDP 841 Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984 L + + S G +G+ L ++ G G L P D Sbjct: 842 GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR-------------GYPGNPGILGPPGED 888 Query: 985 GL--------GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDP 1036 G+ PP P P T PG R P +P +R P K Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGT--PGQRGSPG--IPGVKG---------QRGTPGAKGE 935 Query: 1037 RKRKARGGAWGKELILKIVQQKNRLREYDFA-SESEEDEQPPPRGPGFRGRRGRGEKRKE 1095 + K G G I ++ K FA + E+ + P PG +G +G Sbjct: 936 QGDK---GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL------ 986 Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155 P P PR G G+ NP EP G R PG P + G Sbjct: 987 ------PGPAGPPGPR-------GDLGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 1156 AREGGPKCADRPSVAPKDPLQVPTNTE-TSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214 G P A RP + LQ SE TRP P T + P Sbjct: 1033 ---GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP-------TGDPGLPGD---- 1078 Query: 1215 EALRSPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272 GEMG PG L P P + G+P G PHG G+ Sbjct: 1079 -------MGKKGEMGQPGPPGHLGPAGPEGA---PGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 1273 LLGGPG-----------------GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPS 1315 LLG PG G + + PA + GE A P P Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP--- 1185 Query: 1316 VLSSKISSFGCDPAGFNRDPLGVP--VAKKGPQPYSSPHS----ELFLGPKDLAGCFLEE 1369 G A +R G P +KG + P E F GP L G + Sbjct: 1186 ---------GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236 Query: 1370 L---HPKPSARDAP-------PASSSCLCQDGEDAGSLEPQLPRSPPGTAET--EPGRAA 1417 P +R +P P S + G D GS+ P+ PPGTA PGR Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKG-DKGSMGHPGPKGPPGTAGDMGPPGRLG 1295 Query: 1418 SPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLP--FACADPPQKTVPSDPP 1469 +P T P LP R DP G + G P PP P PP Sbjct: 1296 APGT-------PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Score = 77.8 bits (190), Expect = 2e-13 Identities = 289/1237 (23%), Positives = 378/1237 (30%), Gaps = 221/1237 (17%) Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPIPKGS 262 PGPP + + P + + + D P + PG ++G P Sbjct: 238 PGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297 Query: 263 RPG-----GSP--RGVSFQFPFPALHGAS-TKPFPADVAGHAFTNGPLVFAFHQPQGAWP 314 +PG G P GV FP L G K D+ F + +Q +G Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG--- 354 Query: 315 EEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372 + GP P + PS P G PG + L GA PG S Sbjct: 355 -DEGTPGPPGPRGARGPQGPSGPPGVPGSPG--SSRPGLRGAPGWPGLKGSKG------- 404 Query: 373 HKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP 432 ER +D +G T G P PG PGPP + GP Sbjct: 405 ---------ERGRPGKDAMG-TPGSPGCAGSPGLPGSP-------GPPGPPGDIVFRKGP 447 Query: 433 PPAR-LP-QLWDPTAAPYPTPPGGP-LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489 P LP L P P G P L T+ + G P L +P Q Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL-----PAVRSSQG-- 542 + SP G + LP G P QG G G G+T P ++ P +R G Sbjct: 508 GLKGSP-GSPGNTGLPGFPGFPGAQG-DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565 Query: 543 ---GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH--GTPSLPPPRVVGASPSESPLPSPA 597 G P G+ P + G Q P G+P P P P P P Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625 Query: 598 TN-TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP--------- 647 T G + P + P S + +PGP GP PP HP G P Sbjct: 626 LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG---PPGHPGPQGPPGIPGSLGKC 682 Query: 648 ----FPSPEPPHSLPTHYQPEPA-----KAFPFPADGLGAEG------------------ 680 P P+ +P P P + FP LG G Sbjct: 683 GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742 Query: 681 ----AFQCLEETP-FPHEGPEVGRGGLQGFPRAPP-PYPTHHFSLSSASLD--------Q 726 A TP FP E G G G P P P + L D + Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802 Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL-----PSPPAAPR 781 C + R L + G R K G + PG PGL P +P Sbjct: 803 QGPPGRCIEGPRGAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPG 859 Query: 782 VPA-DAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFP-----LPASDLDME 835 +P G L G G+D + P P P P Sbjct: 860 IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919 Query: 836 DDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT--P 893 T G + NP S V D+ G +G + K GV P Sbjct: 920 IPGVKGQRGTPGAKGEQGDKGNPG-PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978 Query: 894 ESKAPP--PLPAATPDPQ-----TPRPGDRGCPARGRPKTR-SLGLAPTEADAPSQGRQQ 945 K P PA P P+ T PG+ G RG P + ++G+ ++ + G Sbjct: 979 GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Query: 946 RRGKQ----LKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQA 1001 R G+ + + D G +EG+ G G P + GL P ++ Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG------PTGDPGL---PGDMGKKGEMGQ 1087 Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061 PG P P A S LP + P G G + I K L Sbjct: 1088 PGPPGHLGPAGPEGAP-----GSPGSPGLPGKPGPH------GDLGFKGI------KGLL 1130 Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR-------GEKRKE--VELTQGPREDEPQKPR 1111 P GP G RG +GR GEK + + GPR + + Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190 Query: 1112 KAARQEAGGDGAP--------ANPEEPGGSR--PGPGRSPQARGPSRSLETGAAAREGGP 1161 K R G G P A P P G PGP P A P ++ G G P Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS------TEFTE 1215 AP P ++ + + S+ P P TA + P T Sbjct: 1251 G-------APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 1216 ALRSPPA-----ACAGEMG--------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH 1262 R P GE G PG + P+ PP R D GT K + P Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 1263 GSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297 G+ PG+ G GP G P K +PG Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400 Score = 69.3 bits (168), Expect = 7e-11 Identities = 200/845 (23%), Positives = 263/845 (31%), Gaps = 154/845 (18%) Query: 477 PQSAPLPWPQVLPTARPSPH-GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR---- 531 PQ LP VL A P+ G + G + + G +G G G +PG + Sbjct: 9 PQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPG-SPGQKGFTG 67 Query: 532 -EKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASP 588 E LP + +G G P L G+ P F G +P T V G S Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127 Query: 589 SESP-----LPSPATNTAGSTCSSLSPMSSSPANPSSEESQ------LPGPLGPSAFFHP 637 S+ LP + L +PA E LPG GP P Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187 Query: 638 PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEV 697 P P G P P F FP +G G + E H+G E Sbjct: 188 PGFPGPVG----------------PPGPPGFFGFPG-AMGPRGPKGHMGERVIGHKG-ER 229 Query: 698 GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLL 757 G GL G P PP V++T D N + L Sbjct: 230 GVKGLTG-PPGPPG----------------TVIVTLTGPD-NRTDL-------------- 257 Query: 758 ARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817 + + G + + G PG P P P + G GD +GK Sbjct: 258 -KGEKGDKGAMGEPGPPGPSGLPGESYGSEKG---------APGDPGLQGK--------- 298 Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877 P P P S+ ++ + L+ E +G++ Q D P G R Sbjct: 299 PGKDGVP-GFPGSE-GVKGNRGFPGLMGE--DGIKGQK-------------GDIGPPGFR 341 Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPR--PGDRGCPARGRPKTRSLGLAPTE 935 GP+ + + G E PP P PQ P PG G P RP R G Sbjct: 342 GPTEYYDTYQEKG--DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR--GAPGWP 397 Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP--- 992 S+G + R GK + + G+ +GS G + G D + + PP Sbjct: 398 GLKGSKGERGRPGKDA------MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451 Query: 993 -------RPRRPRTQA----PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKA 1041 P P PG P +P LP + +P R+ K Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511 Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP-----PRGPGFRGRRGRGEKRKEV 1096 G+ G + + E E QP P PG RG+ GR + + Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGR-KGLDGI 570 Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAA 1156 T G + K A E G G P +P PG P P GP E G Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG--EPGLQG 628 Query: 1157 REGGPKCADRPSVA-PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215 +G P P A P+ L V T P P P P + Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVST---------PVPGPPGPPGPPGHPGPQGPPGIPGSL 679 Query: 1216 ALRSPPAACA--GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273 P GE G PG+ P PP + D G P GSL G PG L Sbjct: 680 GKCGDPGLPGPDGEPGI-PGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737 Query: 1274 LGGPG 1278 G G Sbjct: 738 PGAKG 742 Score = 67.4 bits (163), Expect = 3e-10 Identities = 285/1227 (23%), Positives = 374/1227 (30%), Gaps = 204/1227 (16%) Query: 1682 AEGDSRPPQDVCLPEPS--KQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739 A G+ PP LP S + G D G K D FP E R Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP-------GSEGVKGNRG 318 Query: 1740 LPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASP 1799 P G + E G Q +G P F P + +G P P G Sbjct: 319 FP-----GLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-----PPGPRG 366 Query: 1800 SHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVS 1857 + QG S G G P + RPG G P G+ G++A P SP C Sbjct: 367 ARGPQGPS-GPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP-GSPGCAG 424 Query: 1858 NTHPSRRSQDPALSPP------------------IRQLQLPGPGVAKSKDGILGLQELTP 1899 + P PP + +PG K + G+L Q P Sbjct: 425 S--PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ--CP 480 Query: 1900 AAQSPPRV-NPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958 PP + GL G G+ +GSPG T LP G A G GL Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP---GAQGDPGLK 537 Query: 1959 GQAEKTQGQGTANQLQPENGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAA 2017 G+ +T LQPE V PG + G T G L KG A Sbjct: 538 GEKGET--------LQPEGQVGVPGDPGLRGQPGRKGLDGIPG-TPGVKGLPGPKGELAL 588 Query: 2018 MSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077 + + P P SP A +G G P+ PGL G P Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPA-------GPAGPPGYGPQ--GEPGLQGTQGVPGAPGPP 639 Query: 2078 SV----GDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133 G+L+ P P P GP P P G LG P P G Sbjct: 640 GEAGPRGELSVSTPVPGP----PGPPGPPGHPGP-QGPPGIPGSLG--KCGDPGLPGPDG 692 Query: 2134 PQQLLACSPAWAPLEEAD-GVQATTDT----GAEDSPVAP--PSLTTSPCDPKEALAGCL 2186 + P + D G T + G P P P L + +P A+ G Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-- 750 Query: 2187 LQGEGS---PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243 G G+ P E +S G + TP + L P R + P P Sbjct: 751 --GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGP 805 Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302 P P A GL+ G + Q G RG GP +G P DR + S Sbjct: 806 PGRCIEGPRGAQGLPGLN----GLKGQQGRRGKTGP----KGDPGIPGLDRSGFPGETGS 857 Query: 2303 PSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK--EPEDPGTPETGRS 2360 P G P P L G D + G G P +PGTP G+ Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP--GQR 915 Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420 G+ +P V G+ P + +P + +G+P Sbjct: 916 GSPGIPGVK--------GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP--------GL 959 Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480 +G+ P N R PG+ K K P P P P Sbjct: 960 KGFAGNPGEKGN---------------------RGVPGMPGLKGLKGLPGPAGPPGPRGD 998 Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP--PPAQGSKEVLRAPG 2538 P EP + P + + G + + G P +P P G + PG Sbjct: 999 LGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057 Query: 2539 SPHSQQLHPPSPT-----EHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593 + PP PT ++ K +P P L P E G Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP----PGHLGPAGPEGAPGSPGSPGLPG 1113 Query: 2594 DSPSHSEGKSNKKRGKLRGRRLREESILP----------VSADVISDGRGSRPSPA---- 2639 H + +G L +R LP + D GR P PA Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD---QGRDGIPGPAGEKG 1170 Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698 A P G P A G + R A PG + G +A G TG + PG Sbjct: 1171 ETGLLRAPP----GPRGNPGAQGAKGDRGAPGFPG-LPGRKGAMGDAGPRGPTGIEGFPG 1225 Query: 2699 DRMLCPGRMDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757 L + G P G +G+ A G GP + +G+ + GS + Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS-----MGHPGPKG 1280 Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP------DNPDTQGGVQGPEGPTP 2811 G + PP G LG P T P QG P NP G + GP GP Sbjct: 1281 PPGTAGDMGPP-GRLGAPGTPGLPGPRGDPG-FQGFPGVKGEKGNPGFLGSI-GPPGPI- 1336 Query: 2812 DASGSSAKDPPSLFDDEVSFSQLFPPG 2838 K PP + D + + PG Sbjct: 1337 -----GPKGPPGVRGDPGTLKIISLPG 1358 Score = 66.6 bits (161), Expect = 5e-10 Identities = 282/1189 (23%), Positives = 366/1189 (30%), Gaps = 225/1189 (18%) Query: 65 PRQAR--DGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122 PR AR G PP + G SS PG RG+P P + R A G+P Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP--- 420 Query: 123 GIASSRTKPTLDETPENP-----------------QLEAAQLPEVDTPQG-PG---TGAP 161 G A S P P P L + +P VD P+G PG T P Sbjct: 421 GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP 480 Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP 221 PG P P G ++ + SP T P PG P ++G L+ Sbjct: 481 YIPGPPGLPGLPGLH--GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538 Query: 222 GSYPEYQASGADSWP--PAAENSFPGANF-----GVPPAEPEPIPKGSRPGGSPRGVSFQ 274 Q G P P PG G P + P PKG +G Q Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKG--DQ 595 Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSP 334 P P G+ P PA AG P G P+ G +P P P Sbjct: 596 GP-PGDPGSPGSPGPAGPAG--------------PPGYGPQGEPGLQGTQGVPGAPGP-- 638 Query: 335 LPCYQGQPGGLNRHSDLSGALSSPG-AAHSAPR---PFSDSLHKSLTKILPERPPSAQDG 390 P G G L+ + + G PG H P+ SL K LP P + G Sbjct: 639 -PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP--GPDGEPG 695 Query: 391 LGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY 448 + GPP + FPG G PG ++ PG P P L P Sbjct: 696 IPGIGFPGPPGPKGDQGFPG----TKGSLGCPG----KMGEPGLPGK--PGLPGAKGEPA 745 Query: 449 PTPPGGPLAATRSMFFNGQPS-PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP 507 PGGP G P PG+R HG L LP Sbjct: 746 VAMPGGP----------GTPGFPGER-----------------GNSGEHGEIGLPGLPGL 778 Query: 508 AGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGV 565 G P G G G G+ P E+ P R +G G+ L NG+ + Sbjct: 779 PGTP-GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR------ 831 Query: 566 AQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPS---- 619 + + P G P +P G S P + + G + P+ P NP Sbjct: 832 -RGKTGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQ-GEMGPLGQRGYPGNPGILGP 884 Query: 620 -SEESQL-----PGPLGPSAFFHPPTHPQETGSP-FPSPEPPHSLPTHYQPEPAKAFPFP 672 E+ + PG +GP P P + GSP P + P + K P P Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944 Query: 673 AD-----GLGAEGAFQCLEETPFPHEGPEV----GRGGLQGFP-RAPPPYPTHHFSLSS- 721 ++ G E + P V G GL+G P A PP P + Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004 Query: 722 ----------ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG-- 769 S+ + + + F GL G + PG Sbjct: 1005 PGEPGLRGIPGSMGNMGM-----PGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059 Query: 770 ---PPGLPSPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPF 825 PG P P P +P D G + G A EG + LP Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----- 1114 Query: 826 PLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPL 885 P P DL + L L + G P P G RG + Sbjct: 1115 PGPHGDLGFKGIKGL--LGPPGIRGPPGLPGFP----------GSPGPMGIRGDQGRDGI 1162 Query: 886 KSKAGVTPES--KAPPPLPAATPDPQTPRPGDRGCPA-RGRP-KTRSLGLAPTEADAPSQ 941 AG E+ PP P P Q + GDRG P G P + ++G A + Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221 Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL----GERPPPRPRRP 997 G G + + G GS G G G+ G P P+ P Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281 Query: 998 RTQAPGSRADPAPRVPRAAALPEETRSSRRRRLP-PRKDPRKRKARG--GAWGKELILKI 1054 PG+ D P P + LP PR DP + G G G L Sbjct: 1282 ----PGTAGDMGP--------PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329 Query: 1055 VQQKNRLREYDFASESEEDEQPPPRGP-GFRGRRGRGEKRKEVELTQGPREDEPQKPRKA 1113 + P P GP G G RG K + L P P P + Sbjct: 1330 I------------------GPPGPIGPKGPPGVRGDPGTLKIISLPGSP--GPPGTPGEP 1369 Query: 1114 ARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPK 1162 Q G P P G R PG+ + P + E G +G P+ Sbjct: 1370 GMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPE 1418 Score = 58.9 bits (141), Expect = 9e-08 Identities = 116/476 (24%), Positives = 150/476 (31%), Gaps = 78/476 (16%) Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488 G PG+K +P + +PG A PG PRG P L + + Sbjct: 964 GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG-----PRGDLGSTGNPGEPGLRGIPGSMG 1018 Query: 3489 ----PST-----TKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRG 3539 P + T G+P RP P H ++G + + E P P P G Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPG-PPGPTGDPGLPG 1077 Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG----QDAEGKRAPLVFSG 3594 D G + +P G GP P LP +PG G + +G P G Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137 Query: 3595 KRRAPGARGRCAPDHFQEDHLLQ-----KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649 PG G P + D ++ + + + GPRG G Q Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN---------PGAQ 1188 Query: 3650 SSSKDRSAASTPS----KALKFPVHPRKAVGSLA-------PGELARGTENGMKPATPKA 3698 + DR A P K PR G PG + G P + Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248 Query: 3699 KPG-PSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756 PG P G GS G K GS P P P + P R Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPG--------------PKGPPGTAGDMGPPGRL 1294 Query: 3757 QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP 3816 A P G GP G P +G K +KG PG +GS G P P P Sbjct: 1295 GA------PGTPGLPGPRGD--PGFQGFPGVKGEKGN-PG-----FLGSIG--PPGPIGP 1338 Query: 3817 PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 P + P L P S P P + EPG LG P+G+P Sbjct: 1339 KGPPGVRGDPG-TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Score = 46.2 bits (108), Expect = 6e-04 Identities = 119/452 (26%), Positives = 148/452 (32%), Gaps = 83/452 (18%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG+PGQK LP + PG P GS + LP Sbjct: 57 PGSPGQKGFTGPEGLPGPQGPKGFPG--------LPGLTGSKGVRGISGLPGF------- 101 Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP--PPSLS----PFPAALADGRGDC 3541 S + G P T + GC Q P P +L P A L +G Sbjct: 102 --SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 3542 AL--DGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAP 3599 A D L+ + PG+PGP Q LP P P G P F G P Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGP-------VGPPGPPGFFG---FP 206 Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP---AGCQSSSKDRS 3656 GA G P + ++ + E + GP GT + T P + D+ Sbjct: 207 GAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIV-TLTGPDNRTDLKGEKGDKG 265 Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG-------PSSQGS 3707 A P P P S PGE + G+E G P P + KPG P S+G Sbjct: 266 AMGEPG-----PPGP-----SGLPGE-SYGSEKG-APGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 3708 GSPR--PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765 R PG G + Q G + P + + E P GP Sbjct: 314 KGNRGFPGLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-------PPGP 364 Query: 3766 REA-GEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824 R A G QGP G G SS +G P S G GR P +P Sbjct: 365 RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAG 424 Query: 3825 TPSRVLPTKPKPNSQNKPRPPPS-EQRKAEPG 3855 +P LP P P P PP RK PG Sbjct: 425 SPG--LPGSPGP-----PGPPGDIVFRKGPPG 449 Score = 43.9 bits (102), Expect = 0.003 Identities = 113/440 (25%), Positives = 133/440 (30%), Gaps = 88/440 (20%) Query: 3414 RGGRQPFAFRG-VRRPGAPGQKARALEGTLP--SKRRRVAMPGSAPGPGEDRPPPRGSSP 3470 +G R F G RPG PG + P S+ R PG PG P G Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG--LPGDMGKKG 1083 Query: 3471 ILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP------IRGCELPSNHQECPP 3524 + + P L P G P + P P H I+G P + P Sbjct: 1084 EMGQPGPPGHL---GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--P 1138 Query: 3525 PSLSPFPAALADG--RGDCALDG----ALERPEN---------EASPGSPGPLLQQALPL 3569 P L FP + RGD DG A E+ E +PG+ G + P Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198 Query: 3570 GASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628 LP R GA G G R P G PG G P Sbjct: 1199 FPGLPGRKGAMGD--AGPRGPTGIEGFPGPPGLPGAIIPGQ------------------T 1238 Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGT 3687 GP G+ A P G S S P P G + P G L Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA-- 1296 Query: 3688 ENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR-- 3745 P TP PGP PG K G + P G L S P P P Sbjct: 1297 -----PGTP-GLPGPRGDPGFQGFPGVK---GEKGNP--GFLGSIGPPGPIGPKGPPGVR 1345 Query: 3746 -------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792 SP P P + E G GP G+LGP K K Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQG------EPGPPGPPGNLGPCGPRGKPGKDGKP 1399 Query: 3793 QVPGPARSE-SVGSFGRAPS 3811 PGPA + + GS G S Sbjct: 1400 GTPGPAGEKGNKGSKGEPES 1419 Score = 40.8 bits (94), Expect = 0.027 Identities = 117/495 (23%), Positives = 146/495 (29%), Gaps = 74/495 (14%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG PG K LP + +A+ G G P SP + + P E Sbjct: 571 PGTPGVKG------LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP 624 Query: 3488 APSTTKGWPETLERPVDP-------VTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG 3539 T+G P P + V+ P+ G P P P P P +L G Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL----G 680 Query: 3540 DCALDGALERPENEAS------PGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF 3592 C D L P+ E PG PGP Q P SL PG G+ Sbjct: 681 KCG-DPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG--------L 731 Query: 3593 SGKRRAPGARGR--CAPDHFQEDHLLQKEKEVSSSH----MVSEGGPRGTFHKGSATKPA 3646 GK PGA+G A E+ S H + G GT P Sbjct: 732 PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791 Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT-PKAKPG---- 3701 G P + ++ PR A G PG + G + T PK PG Sbjct: 792 GDPGQPGPPGEQGPPGRCIE---GPRGAQG--LPGLNGLKGQQGRRGKTGPKGDPGIPGL 846 Query: 3702 --------------PSSQGSGSP--RPGTKTGGGSQPQPAS----GQLQSETATTPAKPS 3741 P QG P + G G P G + A P P Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906 Query: 3742 FPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPGP 3797 +P P K P GEQG G+ GP E G+ KG P Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966 Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHT 3857 + G G K P P L + P P S PG Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Query: 3858 QRKDRLGKAFPQGRP 3872 ++ LG GRP Sbjct: 1027 GKRGTLGFPGRAGRP 1041 Score = 37.7 bits (86), Expect = 0.23 Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 9/115 (7%) Query: 3176 RGQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAK 3235 RGQ R D G+ G+ V L E A +G + GSPG P G G A Sbjct: 559 RGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAG 614 Query: 3236 KDSPGERAKPRARSTPS-----NPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285 G + +P + T P G A P + + G PGPP P P Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669 Score = 35.0 bits (79), Expect = 1.5 Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%) Query: 3183 LGDLPG-----GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKD 3237 L LPG G+ G A L S P G A G PG G++GE + Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK-GEKGETLQP 546 Query: 3238 S--------PGERAKPRARST---PSNPDGAATPDSASATALA----DAGSPGPPRTTPS 3282 PG R +P + P P P AL+ D G PG P + S Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 3283 PSPDPWAG-------GEPLLQAT 3298 P P AG GEP LQ T Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGT 629 Score = 35.0 bits (79), Expect = 1.5 Identities = 51/199 (25%), Positives = 65/199 (32%), Gaps = 21/199 (10%) Query: 1752 PGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRA 1811 PG+ P GAP P G P H+ + +GD + P G P A GR Sbjct: 1244 PGSRGSP--GAPGPP--GPPGSHV---IGIKGDKGS-MGHPGPKGP-PGTAGDMGPPGRL 1294 Query: 1812 GGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPA 1869 G G PG G P G + +G +L + P + P DP Sbjct: 1295 GA-----PGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349 Query: 1870 LSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPP-RVNPSGLEGGTVEGGKVACGPAQ 1928 I PGP + G+ G P PP + P G G + GK Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQG----EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405 Query: 1929 GSPGGVQVTTLPAVAGHQL 1947 G G P HQL Sbjct: 1406 GEKGNKGSKGEPESLFHQL 1424 Score = 32.3 bits (72), Expect = 9.5 Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 28/116 (24%) Query: 3205 EPAPKHHRGK--RSAGKAAGSPGDPWGQEGEAKKDS----PGERAKPRARSTPS------ 3252 EP P G S G G+PGDP G +G+ KD PG R P Sbjct: 269 EPGPPGPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327 Query: 3253 --------NPDGAATPDSASAT--ALADAGSPGPP-----RTTPSPSPDPWAGGEP 3293 P G P T D G+PGPP R PS P G P Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 92.0 bits (227), Expect = 1e-17 Identities = 324/1383 (23%), Positives = 417/1383 (30%), Gaps = 352/1383 (25%) Query: 31 SQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKR 90 SQ P NT R KG + G +P + R G PP +G P R Sbjct: 97 SQTPGGGNTNFGRGRKGQKGEPGL-----VPVVTGIRGRPGPAGPPGSQGPRGERGPKGR 151 Query: 91 GSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLE------A 144 P+ P G +G P G+ P P +P + + Sbjct: 152 PGPRGPQG-------------IDGEP------GVPGQPGAPGPPGHPSHPGPDGLSRPFS 192 Query: 145 AQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPR 204 AQ+ +D G G+ L PG + L + P T P P Sbjct: 193 AQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGP---------TGPPGEPG 243 Query: 205 PPAP-GPPQSRGTS--PLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKG 261 P P GP SRG P +PG E +G A + PGA G P A P KG Sbjct: 244 DPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGS--PGAR-GFPGAPGLPGLKG 300 Query: 262 SRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTG 321 R G + P G + P G GP + + P+ A G Sbjct: 301 HRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPL---GPRGMPGERGR-LGPQGAPGQR 356 Query: 322 PAYPLPTQPAP-SPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKIL 380 A+ +P +P P PL G PG SG +PG A + Sbjct: 357 GAHGMPGKPGPMGPL----GIPGS-------SGFPGNPGMKGEAGPTGA----------- 394 Query: 381 PERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQL 440 R P G GPP + PG A G D +PG A GP + P Sbjct: 395 --RGPEGPQGQRGETGPPGPVGSPGLPG----AIGTDGTPG-------AKGPTGS--PGT 439 Query: 441 WDPTAAPYPTPPGGPLAATRSMFFNGQP-SPGQRLCLPQSAPLPWPQVLPTARPSPHGME 499 P + P GP +T GQP PG P + P P PHG++ Sbjct: 440 SGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPG--------VPGFKGEAGPKGEPGPHGIQ 491 Query: 500 MLSRLPFPAG--GPEWQGGSQGALGTAGK--TPGPR-----EKLPAVRSSQG-------- 542 P G GP G+ G G G+ PG R + LP + +QG Sbjct: 492 GPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSS 551 Query: 543 ------------GSPALFTYNGMT-DPGAQPLFFGVAQPQVSPHGTPSLP----PPRVVG 585 G P L G+T +PG Q + ++ P G P PP +G Sbjct: 552 GPKGSQGDPGRPGEPGLPGARGLTGNPGVQG-----PEGKLGPLGAPGEDGRPGPPGSIG 606 Query: 586 --ASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ--LPGPLGPSAFFHPPTHP 641 P LP P GS+ P + A + G +GPS PP Sbjct: 607 IRGQPGSMGLPGP----KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLA 662 Query: 642 QETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGG 701 E G P PT +Q P P P EG + G G Sbjct: 663 GERGEQGPPG------PTGFQGLPGPPGP--------------------PGEGGKPGDQG 696 Query: 702 LQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAK 761 + G P A P + +R + + G Sbjct: 697 VPGDPGAVGPLGPRGERGNPG--------------ERGEPGITGLPGEKGMAG---GHGP 739 Query: 762 DGHQRSPGPPGLP---SPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817 DG + SPGP G P PP +P + AG G+ AEG L Sbjct: 740 DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799 Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877 P P P + ++ GPR Sbjct: 800 PGPLGPPGPAGPT--------------------------------------GEKGEPGPR 821 Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEAD 937 G + G E+ + A P +PG +G P G P + D Sbjct: 822 GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP--GEPGQK--------GD 871 Query: 938 APSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRP 997 A S G Q G A G G GL+ G G + PP Sbjct: 872 AGSPGPQ-----------------GLAGSPGPHGPNGVPGLK----GGRGTQGPP----G 906 Query: 998 RTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPP--RKDPRKRKARG--------GAWG 1047 T PGS P P A P + PP R DP G G G Sbjct: 907 ATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPG 966 Query: 1048 KELILKIVQQKNRLREYDFASESEEDEQPPPRGP----GFRGRRG-------RGEKRKEV 1096 + + ED QP P GP G G+RG RGE + + Sbjct: 967 DK------------------GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGE--RGM 1006 Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLET---- 1152 GP P K A GD P P P GS GP P GP+ + T Sbjct: 1007 PGLPGP----AGTPGKVGPTGATGDKGPPGPVGPPGSN-GPVGEPGPEGPAGNDGTPGRD 1061 Query: 1153 GAAAREG-----GPKCADRPSVAPKDPLQVPTNTETSEETRP---------------SLD 1192 GA G GP AP P V + + P L Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP 1121 Query: 1193 FPQ-----EAKEPETAEESAPDSTEFT--EALRSPPAACAGEMGAS--PGLLIPEQPPPS 1243 PQ + + + FT + L PP GE G++ PG P PP Sbjct: 1122 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP-NGEQGSAGIPGPFGPRGPP-- 1178 Query: 1244 RHDTGTPKPSGSLANTAPHGSSPTPGV-GSLLGGPGGTQAPVSHNSKDPPARQPGEFLAP 1302 G PSG N P G PGV GS+ G G + P P PG A Sbjct: 1179 ----GPVGPSGKEGNPGPLGPIGPPGVRGSV--GEAGPEGPPGEPGPPGPPGPPGHLTAA 1232 Query: 1303 VAN 1305 + + Sbjct: 1233 LGD 1235 Score = 79.0 bits (193), Expect = 9e-14 Identities = 284/1159 (24%), Positives = 349/1159 (30%), Gaps = 223/1159 (19%) Query: 1751 EPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGR 1810 EPG QP GAP P G P+ H PD + PF A + + G Sbjct: 163 EPGVPGQP--GAPGPP--GHPS-HPGPD-----------GLSRPFSAQMAGLDEKSGLGS 206 Query: 1811 AGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPAL 1870 G + + G G P G L +G T P DP Sbjct: 207 QVGLMPGSVGPVG-------PRGPQGLQGQQGG------------AGPTGPPGEPGDPGP 247 Query: 1871 SPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGS 1930 PI GP +DG G G E G A+G Sbjct: 248 MGPIGSRGPEGPPGKPGEDG------------------EPGRNGNPGEVGFAGSPGARGF 289 Query: 1931 PGGVQVTTLPAVAGHQLGLEAD----GHWGLLGQAEKTQGQGTANQLQP-----ENG-VS 1980 PG + L GH+ GLE G G G+A T G L P E G + Sbjct: 290 PGAPGLPGLKGHRGHK-GLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG 348 Query: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPS----------- 2029 P G + P GP G + + G ++ EA PT + Sbjct: 349 PQGAPGQRGAHGMP--GKPGPM-GPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG 405 Query: 2030 ---PPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD--SPAP--SVGDL 2082 PP P G++G T SPG + P + G SP P S G Sbjct: 406 ETGPPGPVGSPGLPGAIGTDGTPGAKGPT----GSPGTSGPPGSAGPPGSPGPQGSTGPQ 461 Query: 2083 AACA-PSPTSAAHMPCSLGPLPREDP--LTSPSRAQGGLGGQLP-ASPSCRDPPGPQQLL 2138 P GP P + P G G + P P PPGP Sbjct: 462 GIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGER 521 Query: 2139 ACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP----KEALAGCL-------L 2187 +P +DG+ E PV S DP + L G + Sbjct: 522 G-APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGV 580 Query: 2188 QGE-------GSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKE--KLWES-- 2236 QG G+P ED PPGS+ P L P+ S + K E+ Sbjct: 581 QGPEGKLGPLGAPGEDGRPGPPGSIGI------RGQPGSMGLPGPKGSSGDPGKPGEAGN 634 Query: 2237 ---PGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAG----RGLPGPD--PQSRGAPP 2287 PG+ +P G V PS V GL+ G++ G +GLPGP P G P Sbjct: 635 AGVPGQRGAPGKDGEVGPSGPVGPPGLAGE-RGEQGPPGPTGFQGLPGPPGPPGEGGKPG 693 Query: 2288 HTNPDRMPRGHSSYSP-SNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSS 2346 P P G R +T +P E G GPD P G GT Sbjct: 694 DQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT-- 751 Query: 2347 KEPEDPGTPE-TGRSGATKMPRVTCPSTGL-GLGRTTAPSSTASDFQSDSPQSHRNASHQ 2404 P D G P G G + P G+G A + +D P Sbjct: 752 --PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLP------GPL 803 Query: 2405 TPQGDPLGPQDLKQR--SRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRH 2462 P G P GP K RG P S N +G+ +GP A F G Sbjct: 804 GPPG-PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGE--NGPTG----AVGFAGPQGPDGQ 856 Query: 2463 KARKHRPHPGAPAEPSPAALPAQQPLE----PLAQKCQPPRKKSHRVSGKERPNHSRGDP 2518 K PG P + A P Q L P P K G G Sbjct: 857 PGVK--GEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSA 914 Query: 2519 SHVTQPPP--AQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHP 2576 V P P A G L PG L + V + PA P + D Sbjct: 915 GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGED 974 Query: 2577 KQAEKREGRRWRREPTVDSPSHSEGKSNKKR--GKLRGRRLREESILPVSADVISDGRGS 2634 Q P D P G + ++ G R R LP A G Sbjct: 975 GQ------------PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPA-----GTPG 1017 Query: 2635 RPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQ 2694 + P A+ P + G GE P GP +G D GE G + Sbjct: 1018 KVGPTGATGDKGPPGPVGPPGSNGPVGEPGPE----GPAGNDGTPGRDG---AVGERGDR 1070 Query: 2695 KPPGDRMLCPGRMDGAALGEQPTGQKG-ASARGFWGPRETKALGVCKESGSEPAEDSSRA 2753 PG L PG GA P G G A RG G R P RA Sbjct: 1071 GDPGPAGL-PG-SQGAPGTPGPVGAPGDAGQRGDPGSR-------------GPIGPPGRA 1115 Query: 2754 HSRSEEGVWEENTPPLGPLGFPETSSSPADSTTS-----SCLQGLPDNPDTQG-----GV 2803 R G P GP G D + LQGLP P G G+ Sbjct: 1116 GKRGLPG-------PQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGI 1168 Query: 2804 QGPEGP--TPDASGSSAKD 2820 GP GP P G S K+ Sbjct: 1169 PGPFGPRGPPGPVGPSGKE 1187 Score = 77.4 bits (189), Expect = 3e-13 Identities = 230/869 (26%), Positives = 273/869 (31%), Gaps = 162/869 (18%) Query: 1 MPGER-PRGAPPPT----MTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQA 55 M GE P GA P G+ P SPG P D TP + G+ G Sbjct: 385 MKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGT-DGTPGAKGPTGSPGTSGPP 443 Query: 56 QAMELPEA---------QPRQARDGELKPPSLRGQA-PSSTPGKRG--SPQTPPGRSPLQ 103 + P + Q + + G+ P +G+A P PG G P PPG + Sbjct: 444 GSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR 503 Query: 104 APSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLR 163 P G G P G +R P D P + + P + G P R Sbjct: 504 GPRGDPGTV-GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGR 562 Query: 164 PGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGS 223 PG P P A L + Q P +P RP PG RG QPGS Sbjct: 563 PGEP---GLPGARGLTGNPGVQGPEGKLGPLG--APGEDGRPGPPGSIGIRG----QPGS 613 Query: 224 Y--PEYQASGADSWPP--AAENSFPGANFGVPPAEPEPIPKG--SRPG--------GSPR 269 P + S D P A PG G P + E P G PG G P Sbjct: 614 MGLPGPKGSSGDPGKPGEAGNAGVPGQR-GAPGKDGEVGPSGPVGPPGLAGERGEQGPPG 672 Query: 270 GVSFQ-FPFP-ALHGASTKPFPADVAGHAFTNGPLVFAFHQPQG--------------AW 313 FQ P P G KP V G GPL P+G Sbjct: 673 PTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPL-----GPRGERGNPGERGEPGITGL 727 Query: 314 PEE---AVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSD 370 P E A G GP P + P PS P G PG L G G A P P D Sbjct: 728 PGEKGMAGGHGPDGPKGS-PGPSGTPGDTGPPG-------LQGMPGERGIA-GTPGPKGD 778 Query: 371 SLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAP 430 + E+ G RG P L PG A +G PGP Sbjct: 779 RGG------IGEKGAEGTAGNDGARGLPGPLGP---PGPA-GPTGEKGEPGPR----GLV 824 Query: 431 GPPPARLPQLWDPTAAPYPTPPG-----GPLAATRSMFFNGQPS-PGQRLCLPQSAPLPW 484 GPP +R +P + P G GP G+P PGQ+ A P Sbjct: 825 GPPGSR----GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQK----GDAGSPG 876 Query: 485 PQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--------GSQGALGTAGKTPGPREKLPA 536 PQ L P PHG + +P GG QG GS G +G G P P Sbjct: 877 PQGL-AGSPGPHGP---NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPL 932 Query: 537 VRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSP 596 + G P L DPG+ G P P G P G + P P P Sbjct: 933 GEPGKEGPPGL-----RGDPGSHGRV-GDRGPAGPPGGPGDKGDPGEDGQPGPDGP-PGP 985 Query: 597 ATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHS 656 A T + P LPGP G P + G P P P + Sbjct: 986 AGTTGQRGIVGMPGQRGERGMPG-----LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSN 1040 Query: 657 LPTHYQPEPAKAFPFPADGL-GAEGAF-----------------QCLEETPFPHEGPEVG 698 P EP P DG G +GA Q TP P P G Sbjct: 1041 GPVG---EPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAP--G 1095 Query: 699 RGGLQGFP--RAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCG 754 G +G P R P PP L + D + DR HR F G Sbjct: 1096 DAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKG------HRGFTG 1149 Query: 755 LLLARAKDGHQRSPGPPGLPSPPAAPRVP 783 L G G G+P P PR P Sbjct: 1150 LQGLPGPPGPNGEQGSAGIPG-PFGPRGP 1177 Score = 77.0 bits (188), Expect = 3e-13 Identities = 256/1071 (23%), Positives = 312/1071 (29%), Gaps = 257/1071 (23%) Query: 505 PFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG 564 P PAG P GSQG G G P + P + G P PGA Sbjct: 131 PGPAGPP----GSQGPRGERGPKGRPGPRGPQGIDGEPGVPG--------QPGAP----- 173 Query: 565 VAQPQVSPHGTPSLPPP----RVVGASPSESPLPSPATNTAGSTCSSLSPMS-------- 612 P G PS P P R A + S + G S+ P+ Sbjct: 174 ------GPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQ 227 Query: 613 -----SSPANPSSEESQLPGPLGPSAFFHP---PTHPQETGSPFPSPEPPH--------- 655 + P P E PGP+GP P P P E G P + P Sbjct: 228 GQQGGAGPTGPPGEPGD-PGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGA 286 Query: 656 -------SLPTHYQPEPAKAFPFPADGLGAEGAFQCLEET-PFPHEGP--------EVGR 699 LP K P +GA G+ T P GP E GR Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346 Query: 700 GGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLAR 759 G QG AP H + L + S + G AR Sbjct: 347 LGPQG---APGQRGAHGMPGKPGPMGPLGI--------PGSSGFPGNPGMKGEAGPTGAR 395 Query: 760 AKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPS 819 +G Q G G P P +P +P G + T G + G P P Sbjct: 396 GPEGPQGQRGETGPPGPVGSPGLP-----GAIGTDGTPGAKGPTGSPGTSGP------PG 444 Query: 820 LAATP-FPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRG 878 A P P P + G+ Q +P + F E +GP+G Sbjct: 445 SAGPPGSPGPQGSTGPQ--------------GIRGQPGDPGVPG-----FKGE--AGPKG 483 Query: 879 PSSGHPLKSKAGVT-PESKAPPPLPAATPDPQTPRPGDRGCPA-RGRPKTRSLGLAPTEA 936 H ++ G E K P T P P G+RG P RG P + L Sbjct: 484 EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP-VGERGAPGNRGFPGSDGL------- 535 Query: 937 DAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPP---PR 993 +G Q RG + S G G G GL R GL P P Sbjct: 536 -PGPKGAQGERGP--------VGSSGPKGSQGDPGRPGEPGLPGAR--GLTGNPGVQGPE 584 Query: 994 PRRPRTQAPGSRADPAPR-------VPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046 + APG P P P + LP SS P + GA Sbjct: 585 GKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAP 644 Query: 1047 GKELILKIVQQKNRLREYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQGP 1102 GK+ V + A E E P P G PG G G G K + + P Sbjct: 645 GKD---GEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDP 701 Query: 1103 REDEPQKPR-----KAARQEAGGDGAPAN--------PEEPGGSRPGPGRSPQARGP--- 1146 P PR R E G G P P+ P GS PGP +P GP Sbjct: 702 GAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGS-PGPSGTPGDTGPPGL 760 Query: 1147 -----SRSL--------------ETGAAAREGGPKCADRPS-VAPKDPLQVPTNTETSEE 1186 R + E GA G P + P P PT + Sbjct: 761 QGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG-PTGEKGEPG 819 Query: 1187 TRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMG--ASPGLLIPEQPPPSR 1244 R + P P + E+ P AG G PG+ P + Sbjct: 820 PRGLVGPPGSRGNPGSRGENGPTGA----------VGFAGPQGPDGQPGVKGEPGEPGQK 869 Query: 1245 HDTGTPKPSGSLANTAPHGSSPTPGV---GSLLGGPGGTQAPVSHNSKDPPARQPGEFLA 1301 D G+P P G + PHG + PG+ G PG T P S PP Sbjct: 870 GDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPP--------G 921 Query: 1302 PVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKD 1361 P P PAG PLG P + P P S +G + Sbjct: 922 PAGAPG--------------------PAG----PLGEPGKEGPPGLRGDPGSHGRVGDRG 957 Query: 1362 LAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRA-ASPP 1420 AG PP GED +P P PPG A T R P Sbjct: 958 PAG---------------PPGGPGDKGDPGEDG---QPG-PDGPPGPAGTTGQRGIVGMP 998 Query: 1421 TLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYP 1471 P LP P G A D G P PP P P P Sbjct: 999 GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPP-GPVGPPGSNGPVGEPGP 1048 Score = 75.5 bits (184), Expect = 1e-12 Identities = 212/840 (25%), Positives = 275/840 (32%), Gaps = 190/840 (22%) Query: 3 GER-PRGAPPPTMTGDLQ-----PRQVASS--PGHPSQP-PLEDNTPATRTTKGAREAGG 53 GER P+G P P + P Q + PGHPS P P + P + G E G Sbjct: 144 GERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSG 203 Query: 54 QAQAMEL------------PEA-QPRQARDGELKPPSLRGQ-APSSTPGKRGSPQTPPGR 99 + L P+ Q +Q G PP G P G RG P+ PPG+ Sbjct: 204 LGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRG-PEGPPGK 262 Query: 100 SPLQA-PSRLAGRAE----GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQ 154 P R E GSP R G + P L + LE + EV P Sbjct: 263 PGEDGEPGRNGNPGEVGFAGSPGAR---GFPGAPGLPGLKGHRGHKGLEGPK-GEVGAPG 318 Query: 155 GPGTGAPLRP----------GLP----RTEAQPAAEELGFHRCFQEP------------- 187 G P P G+P R Q A + G H +P Sbjct: 319 SKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSG 378 Query: 188 -PSSFTSTNYTSPSATPRPPAP-------GPPQSRGTSPLQPGSYPEYQASGADSWPPAA 239 P + P+ P P GPP G SP PG A G D P A Sbjct: 379 FPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVG-SPGLPG------AIGTDGTPGAK 431 Query: 240 ENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTN 299 + G P + P G + P+G+ Q P + G + P G Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQ 491 Query: 300 GPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPG 359 GP+ P E GP T P P+ +G PG NR S L P Sbjct: 492 GPI---------GPPGEEGKRGPRGDPGTVGPPGPVG-ERGAPG--NRGFPGSDGLPGPK 539 Query: 360 AAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTS 419 A ER P G ++G P + PG A G+ + Sbjct: 540 GAQG------------------ERGPVGSSGPKGSQGDPGRPGEPGLPG----ARGLTGN 577 Query: 420 PGPPDTE-----LAAPGP-----PPARLPQLWDPTAAPYPTP------PGGPLAATRSMF 463 PG E L APG PP + P + P P PG P A + Sbjct: 578 PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGV 637 Query: 464 FNGQPSPGQRLCLPQSAPLPWPQVL----PTARPSPHGMEMLSRLPFP---AGGPEWQG- 515 + +PG+ + S P+ P + P P G + L P P G P QG Sbjct: 638 PGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGV 697 Query: 516 ----GSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571 G+ G LG G+ P E+ + G + +G P P Sbjct: 698 PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP----------G 747 Query: 572 PHGTPSLPPPRVVGASPSESPL---PSP-----------ATNTAGSTCSSLSP---MSSS 614 P GTP P + P E + P P A TAG+ + P Sbjct: 748 PSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807 Query: 615 PANPSSEESQLPGP---LGPSAFFHPPTHPQETGSP----FPSPEPPHSLPTHYQPEPAK 667 PA P+ E+ + PGP +GP P E G F P+ P P + EP + Sbjct: 808 PAGPTGEKGE-PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQP-GVKGEPGE 865 Query: 668 AFPFPADGLGAEGAFQCLEETPFPH-----EGPEVGRG-----GLQGFP----RAPPPYP 713 P G+ G Q L +P PH G + GRG G GFP R PP P Sbjct: 866 --PGQKGDAGSPGP-QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGP 922 Score = 74.7 bits (182), Expect = 2e-12 Identities = 186/734 (25%), Positives = 227/734 (30%), Gaps = 141/734 (19%) Query: 2 PGERPRGAPPPTMTGDLQPRQVA-----SSPGHPSQPPLEDNT--PATRTTKGAREAGGQ 54 PGE R PP ++ QP + S G P +P N P R G G Sbjct: 593 PGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGP 652 Query: 55 AQAMELPEAQPRQARDGELKPPSLRG-QAPSSTPGKRGSP--QTPPGRSPLQAPSRLAGR 111 + + P + G P +G P PG+ G P Q PG P L R Sbjct: 653 SGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGP--LGPR 710 Query: 112 AEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQG-PG-TGAPLRPGLPRT 169 E P R +P + P + P D P+G PG +G P G P Sbjct: 711 GERGNP--------GERGEPGITGLPGEKGMAGGHGP--DGPKGSPGPSGTPGDTGPPGL 760 Query: 170 EAQPAAEEL-------GFHRCFQEPPSSFTSTN-----YTSPSATPRPPAP--------- 208 + P + G E + T+ N P P P P Sbjct: 761 QGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGP 820 Query: 209 ----GPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRP 264 GPP SRG PGS E +GA + A P GV EP KG Sbjct: 821 RGLVGPPGSRGN----PGSRGENGPTGAVGF---AGPQGPDGQPGVKGEPGEPGQKGDAG 873 Query: 265 GGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAY 324 P+G++ P HG + P G G F + P A GPA Sbjct: 874 SPGPQGLAGS---PGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG 930 Query: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384 PL +P P +G PG R D G PG P D P+ P Sbjct: 931 PLG-EPGKEGPPGLRGDPGSHGRVGD-RGPAGPPGGPGDKGDPGEDGQPG------PDGP 982 Query: 385 PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPG-PPPARLPQLWDP 443 P GP + QR G+ PG E PG P PA P P Sbjct: 983 P----------GPAGTTGQR----------GIVGMPGQRG-ERGMPGLPGPAGTPGKVGP 1021 Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503 T A P GP+ S G+P P P R G Sbjct: 1022 TGATGDKGPPGPVGPPGSNGPVGEPGPEG----------PAGNDGTPGRDGAVGERGDRG 1071 Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFF 563 P PAG P GSQGA GT G P + + Q G P G P + Sbjct: 1072 DPGPAGLP----GSQGAPGTPGPVGAPGD------AGQRGDPG---SRGPIGPPGRAGKR 1118 Query: 564 GVAQPQ-----VSPHGTPSLPPPRVVGASPSESPLPS-PATNTAGSTCSSLSPMS----S 613 G+ PQ HG + LP P N + P Sbjct: 1119 GLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPP 1178 Query: 614 SPANPSSEESQLPGPLGP---------SAFFHPPTHPQETGSPFPSPEPPH------SLP 658 P PS +E PGPLGP P P E G P P P H + Sbjct: 1179 GPVGPSGKEGN-PGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIM 1237 Query: 659 THY---QPEPAKAF 669 HY P+P F Sbjct: 1238 GHYDESMPDPLPEF 1251 Score = 72.4 bits (176), Expect = 8e-12 Identities = 317/1329 (23%), Positives = 405/1329 (30%), Gaps = 294/1329 (22%) Query: 204 RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVP--PAEPEPIPKG 261 RP GPP S+G P + P G GVP P P P Sbjct: 130 RPGPAGPPGSQG---------PRGERGPKGRPGPRGPQGIDGEP-GVPGQPGAPGPPGHP 179 Query: 262 SRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTG 321 S PG P G+S +PF A +AG +G G P G Sbjct: 180 SHPG--PDGLS-------------RPFSAQMAGLDEKSG-----LGSQVGLMPGSVGPVG 219 Query: 322 PAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILP 381 P P Q GQ GG +G PG P P + P Sbjct: 220 PRGPQGLQ----------GQQGG-------AGPTGPPGEPGD-PGPMGPIGSRG-----P 256 Query: 382 ERPPS--AQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT-------------- 425 E PP +DG G P + PG A G +PG P Sbjct: 257 EGPPGKPGEDGEPGRNGNPGEVGFAGSPG----ARGFPGAPGLPGLKGHRGHKGLEGPKG 312 Query: 426 ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWP 485 E+ APG + P GP+ A + G P RL PQ AP Sbjct: 313 EVGAPG--------------SKGEAGPTGPMGAMGPLGPRGMPGERGRLG-PQGAP---- 353 Query: 486 QVLPTARPSPHGMEMLSRLPFPAGGPEWQG--GSQGALGTAGKTPGPREKLPAVRSSQGG 543 + HGM P G P G G+ G G AG T + P + + G Sbjct: 354 -----GQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408 Query: 544 SPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGS 603 P G+ G P SP GT P A P SP P +T G Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSP-GTSGPPG----SAGPPGSPGPQGSTGPQG- 462 Query: 604 TCSSLSPMSSSPANPSSEESQLP-GPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQ 662 + P P + P G GP P P E G P +P P Sbjct: 463 ----IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV 518 Query: 663 PEPA----KAFPFPADGL----GAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP--PPY 712 E + FP +DGL GA+G E P GP+ G QG P P P Sbjct: 519 GERGAPGNRGFP-GSDGLPGPKGAQG-----ERGPVGSSGPK----GSQGDPGRPGEPGL 568 Query: 713 PTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPG 772 P + + + L G L A +DG PG G Sbjct: 569 PGARGLTGNPGVQGPEGKL----------------------GPLGAPGEDGRPGPPGSIG 606 Query: 773 LPSPPAAPRVP----ADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLP 828 + P + +P + G A + G A GKD + PS P L Sbjct: 607 IRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVG----PSGPVGPPGLA 662 Query: 829 ASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSK 888 + G + P D A P GPRG + + Sbjct: 663 GERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGA-VGPLGPRGERGNPGERGE 721 Query: 889 AGVT--PESKAP-----PPLPAATPDPQTPRPGDRGCPA-RGRPKTRSLGLAPTEADAPS 940 G+T P K P P +P P + PGD G P +G P R G+A T Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGP-SGTPGDTGPPGLQGMPGER--GIAGTPGPKGD 778 Query: 941 QGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRA--SGLRPRRNDG-LGERPPPRPRR- 996 +G +G AEG+ G R L P G GE+ P PR Sbjct: 779 RGGIGEKG---------------AEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGL 823 Query: 997 ---PRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELIL 1052 P ++ PGSR + P A P+ + P + +K A G+ G + + Sbjct: 824 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDA--GSPGPQGLA 881 Query: 1053 KIVQQKNRLREYDFASESEEDEQPPPRGP----GFRGRRGRGEKRKEVELTQGP--REDE 1106 P P GP G +G RG TQGP Sbjct: 882 G---------------------SPGPHGPNGVPGLKGGRG----------TQGPPGATGF 910 Query: 1107 PQKPRKAARQEAGGDGAPANP-EEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCAD 1165 P + G PA P EPG P PG R + G A GGP Sbjct: 911 PGSAGRVGPPGPAGAPGPAGPLGEPGKEGP-PGLRGDPGSHGRVGDRGPAGPPGGPGDKG 969 Query: 1166 RPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACA 1225 P + P + R + P + E P T + P Sbjct: 970 DPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPG----KVGPTGAT 1025 Query: 1226 GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVS 1285 G+ G PG P PP S G P P G P G+ TPG +G G P Sbjct: 1026 GDKGP-PG---PVGPPGSNGPVGEPGPEG------PAGNDGTPGRDGAVGERGDRGDP-- 1073 Query: 1286 HNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVP--VAKK 1343 PA PG AP P P + DP +R P+G P K+ Sbjct: 1074 -----GPAGLPGSQGAP-GTPGPVGAPGDAGQRG-------DPG--SRGPIGPPGRAGKR 1118 Query: 1344 GPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPR 1403 G P + G G ++ H + P + G AG P PR Sbjct: 1119 GLPGPQGPRGD--KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQG-SAGIPGPFGPR 1175 Query: 1404 SPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPP-LYGSLSANRDSGLPFACADPPQK 1462 PPG G+ +P P+ PP + GS+ G PP + Sbjct: 1176 GPPGPVGPS-GKEGNPG-----------PLGPIGPPGVRGSVGEAGPEG-------PPGE 1216 Query: 1463 TVPSDPPYP 1471 P PP P Sbjct: 1217 PGPPGPPGP 1225 Score = 59.7 bits (143), Expect = 6e-08 Identities = 117/455 (25%), Positives = 154/455 (33%), Gaps = 95/455 (20%) Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488 G PG K + + P + +PG PG+D EV Sbjct: 615 GLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKD-----------------------GEVG 651 Query: 3489 PSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALE 3548 PS G P + +G P+ Q P P P G G Sbjct: 652 PSGPVGPPGLAGERGE------QGPPGPTGFQGLPGPPGPP-------GEGG-------- 690 Query: 3549 RPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPD 3608 +P ++ PG PG + PLG PR G RG G+R PG G Sbjct: 691 KPGDQGVPGDPGAV----GPLG---PR-GERGN-----------PGERGEPGITG----- 726 Query: 3609 HFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSA---TKPAGCQSSSKDRSAASTPS-KA 3664 L EK ++ H GP+G+ T P G Q +R A TP K Sbjct: 727 -------LPGEKGMAGGH--GPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKG 777 Query: 3665 LKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG-GGSQPQ 3723 + + + A G+ A + ARG P P GP+ + G P P G GS+ Sbjct: 778 DRGGIGEKGAEGT-AGNDGARGLPG---PLGPPGPAGPTGE-KGEPGPRGLVGPPGSRGN 832 Query: 3724 PAS-GQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPRE---AGEQGPHGSLG- 3778 P S G+ A A P P P + P K P AG GPHG G Sbjct: 833 PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGV 892 Query: 3779 PKEKGESSTKRKKGQVPGPARSESVGSFGRAPS-APDKPPRTPRKQATPS-RVLP-TKPK 3835 P KG T+ G P + VG G A + P P P K+ P R P + + Sbjct: 893 PGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGR 952 Query: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQG 3870 + PP K +PG + G P G Sbjct: 953 VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAG 987 Score = 59.3 bits (142), Expect = 7e-08 Identities = 134/534 (25%), Positives = 171/534 (32%), Gaps = 125/534 (23%) Query: 3414 RGGRQPFAFRG-VRRPGAPGQKA-RALEGTL--PSKRRRVAMPGSAPGPGEDR-PPPRGS 3468 +G P +G + PG G++ R GT+ P PG+ PG D P P+G+ Sbjct: 482 KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGA 541 Query: 3469 S----PILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPP 3524 P+ S G P ++G P RP +P RG Q P Sbjct: 542 QGERGPVGSSG-------------PKGSQGDPG---RPGEPGLPGARGLTGNPGVQG-PE 584 Query: 3525 PSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDA 3583 L P A DGR PG PG + + P LP P G+ G Sbjct: 585 GKLGPLGAPGEDGR-----------------PGPPGSIGIRGQPGSMGLPGPKGSSGDPG 627 Query: 3584 E-GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSA 3642 + G+ G+R APG G P L E+ +G P T +G Sbjct: 628 KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERG-------EQGPPGPTGFQGLP 680 Query: 3643 TKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELA----------RGTENGMK 3692 P K P+ PR G+ PGE +G G Sbjct: 681 GPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGN--PGERGEPGITGLPGEKGMAGGHG 738 Query: 3693 PATPKAKPGPSS----------QGSGSPR-----PGTK-TGGGSQPQPASGQLQSETA-- 3734 P PK PGPS QG R PG K GG + A G ++ A Sbjct: 739 PDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARG 798 Query: 3735 -------TTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLG--------- 3778 PA P+ P P L ++ P GE GP G++G Sbjct: 799 LPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG---NPGSRGENGPTGAVGFAGPQGPDG 855 Query: 3779 -PKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPD------------KPPRTPRKQAT 3825 P KGE +KG P GS G P P+ PP + Sbjct: 856 QPGVKGEPGEPGQKGDAGSPGPQGLAGSPG--PHGPNGVPGLKGGRGTQGPPGATGFPGS 913 Query: 3826 PSRVLPTKPKPNSQNKPRPPPSEQRK-------AEPGHTQRKDRLGKAFPQGRP 3872 RV P P P P P E K +PG R G A P G P Sbjct: 914 AGRVGP--PGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGP 965 Score = 55.1 bits (131), Expect = 1e-06 Identities = 209/874 (23%), Positives = 265/874 (30%), Gaps = 175/874 (20%) Query: 2050 GSEGRTPERASS--PGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDP 2107 GS+G ER PG P G+ P G A P P +H P D Sbjct: 138 GSQGPRGERGPKGRPGPRGPQGIDGEPGVP--GQPGAPGP-PGHPSH--------PGPDG 186 Query: 2108 LTSPSRAQ-------GGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG 2160 L+ P AQ GLG Q+ P P GP+ G Q Sbjct: 187 LSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPR----------------GPQGLQGQQ 230 Query: 2161 AEDSPVAPPSLTTSPCDPKEALAGCLLQGE-GSPLEDPS---SWPPGSVSAVTCTHSGDT 2216 P PP P P + +G G P ED + PG V + Sbjct: 231 GGAGPTGPPGEPGDP-GPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGF 289 Query: 2217 PKDSTLRIPEDSRKEKLWESP-GRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGL 2275 P L + R K E P G +P G P+ + A G P G + GR Sbjct: 290 PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLG-PRGMPGERGRLG 348 Query: 2276 PGPDPQSRGAPPHTNPDRM-PRGH-----SSYSPSNTARLGHREGQAVTAVPTEPPTLQG 2329 P P RGA H P + P G SS P N G G P P +G Sbjct: 349 PQGAPGQRGA--HGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA-GPTGARGPEGPQGQRG 405 Query: 2330 -AGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTAS 2388 GP P G G + TG G + P P G +T P Sbjct: 406 ETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465 Query: 2389 DFQSDSPQSHRNASHQTPQGDPLGPQDLK--------QRSRGYKKKPASTENGQWKGQAP 2440 Q P P+G+P GP ++ + RG + P + P Sbjct: 466 --QPGDPGVPGFKGEAGPKGEP-GPHGIQGPIGPPGEEGKRGPRGDPGTV--------GP 514 Query: 2441 HGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRK 2500 GPV R PG +R PG+ P P AQ P+ Sbjct: 515 PGPV-------GERGAPG--------NRGFPGSDGLPGPKG--AQGERGPV--------- 548 Query: 2501 KSHRVSGKERPNHSRGDPSHVTQP-----------PPAQGSKEVLRAPGSPHSQQLHPPS 2549 G P S+GDP +P P QG + L G+P P Sbjct: 549 ------GSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP 602 Query: 2550 PTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGK 2609 + P P + D P +A R P D G Sbjct: 603 GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG-- 660 Query: 2610 LRGRRLREESILPVSADVISD-----GRGSRPSPAMASY---AASPSHCLSVEGGPEADG 2661 L G R + P + G G +P A P G P G Sbjct: 661 LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG 720 Query: 2662 EQPPRLATL----------GPGVMEGAAETDQEALCAGETGAQKPPGDRMLC--PG-RMD 2708 E P + L GP +G+ G G Q PG+R + PG + D Sbjct: 721 E--PGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD 778 Query: 2709 GAALGEQPTGQKGAS----ARGFWGPRETKALGVCKESG--SEPAEDSSRA-----HSRS 2757 +GE+ G +G + ARG GP LG +G E E R SR Sbjct: 779 RGGIGEK--GAEGTAGNDGARGLPGP-----LGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831 Query: 2758 EEGVWEENTP--------PLGPLGFPETSSSPAD-----STTSSCLQGLPDNPDTQGGVQ 2804 G EN P P GP G P P + S QGL +P G Sbjct: 832 NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSP----GPH 887 Query: 2805 GPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPG 2838 GP G G + PP S ++ PPG Sbjct: 888 GPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921 Score = 53.9 bits (128), Expect = 3e-06 Identities = 104/439 (23%), Positives = 139/439 (31%), Gaps = 49/439 (11%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPP-PRGSSPILSEGSLPALLHLCSE 3486 PG PG K L + V PGS GE P P G+ L +P Sbjct: 293 PGLPGLKGHRGHKGLEGPKGEVGAPGS---KGEAGPTGPMGAMGPLGPRGMPG------- 342 Query: 3487 VAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546 +G P H + G P P S P + G G Sbjct: 343 -----ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397 Query: 3547 LERPENEASPGSPGPLLQQALP--LGASLPRPGARG-QDAEGKRAPLVFSGKRRAPGARG 3603 G PGP+ LP +G PGA+G + G P +G +PG +G Sbjct: 398 EGPQGQRGETGPPGPVGSPGLPGAIGTD-GTPGAKGPTGSPGTSGPPGSAGPPGSPGPQG 456 Query: 3604 RCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSK 3663 P + + + E GP+G P G R P Sbjct: 457 STGPQGIR-----GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG- 510 Query: 3664 ALKFPVHPRKAVGSL-APGELARGTENGMK-PATPKAKPGPSSQGSGSPRPGTKTGGGSQ 3721 V P VG APG +G+ P + + GP GS P+ G++ G Sbjct: 511 ----TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP--VGSSGPK-GSQGDPGRP 563 Query: 3722 PQP----ASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSL 3777 +P A G + P P +P + P + P G GP GS Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623 Query: 3778 G-PKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKP 3836 G P + GE+ GQ P + VG PS P PP ++ PT Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVG-----PSGPVGPPGLAGERGEQGPPGPT---- 674 Query: 3837 NSQNKPRPPPSEQRKAEPG 3855 Q P PP +PG Sbjct: 675 GFQGLPGPPGPPGEGGKPG 693 Score = 53.9 bits (128), Expect = 3e-06 Identities = 137/539 (25%), Positives = 171/539 (31%), Gaps = 124/539 (23%) Query: 873 PSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLA 932 P GP GP AG T E P P P PG RG T ++G A Sbjct: 802 PLGPPGP---------AGPTGEKGEPGPRGLVGPPGSRGNPGSRG----ENGPTGAVGFA 848 Query: 933 PTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP 992 + G + G+ + + D S G +GS G +G+ P G G + PP Sbjct: 849 GPQGPDGQPGVKGEPGEPGQ--KGDAGSPGPQGLAGSPGPHGPNGV-PGLKGGRGTQGPP 905 Query: 993 RPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPP--RKDPRKRKARG------- 1043 T PGS P P A P + PP R DP G Sbjct: 906 GA----TGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGP 961 Query: 1044 -GAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGP----GFRGRRG-------RGE 1091 G G + + ED QP P GP G G+RG RGE Sbjct: 962 PGGPGDK------------------GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGE 1003 Query: 1092 KRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLE 1151 + + GP P K A GD P P P GS GP P GP+ + Sbjct: 1004 RG--MPGLPGPAGT----PGKVGPTGATGDKGPPGPVGPPGSN-GPVGEPGPEGPAGNDG 1056 Query: 1152 T----GAAAREG-----GPKCADRPSVAPKDPLQVPTNTETSEETRPS------------ 1190 T GA G GP AP P V + + P Sbjct: 1057 TPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116 Query: 1191 ---LDFPQ-----EAKEPETAEESAPDSTEFT--EALRSPPAACAGEMGAS--PGLLIPE 1238 L PQ + + + FT + L PP GE G++ PG P Sbjct: 1117 KRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP-NGEQGSAGIPGPFGPR 1175 Query: 1239 QPP----PSRHD--------TGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP--- 1283 PP PS + G P GS+ P G PG G PG A Sbjct: 1176 GPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGD 1235 Query: 1284 -VSHNSKDPPARQPGEFLAPVANPSSTACPKPSV------LSSKISSFGCDPAGFNRDP 1335 + H + P P EF A P P V LSS+I + P G + P Sbjct: 1236 IMGHYDESMPDPLP-EFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMR-SPDGSKKHP 1292 Score = 52.0 bits (123), Expect = 1e-05 Identities = 290/1238 (23%), Positives = 372/1238 (30%), Gaps = 243/1238 (19%) Query: 1082 GFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSP 1141 G RGR G +QGPR + K R R G DG P P +PG PGP P Sbjct: 126 GIRGRPGPAGPPG----SQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGA--PGPPGHP 179 Query: 1142 QARGP---SRSLET-------------------------------GAAAREGGPKCADRP 1167 GP SR G ++GG P Sbjct: 180 SHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPP 239 Query: 1168 SVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP-------ETAEESAPDSTEFTEALRSP 1220 P DP + E P P E EP E +P + F A P Sbjct: 240 G-EPGDPGPMGPIGSRGPEGPPGK--PGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP 296 Query: 1221 PAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGT 1280 G G GL P+ + G P+G + P G PG LG G Sbjct: 297 --GLKGHRG-HKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQG-- 351 Query: 1281 QAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPV 1340 AP + P + PG + P+ P S+ P + + G R P G P Sbjct: 352 -APGQRGAHGMPGK-PGP-MGPLGIPGSSGFPGNPGMKGEAGPTGA------RGPEG-PQ 401 Query: 1341 AKKG----PQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGS 1396 ++G P P SP +G G P S PP S+ G GS Sbjct: 402 GQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTS---GPPGSAGPPGSPGPQ-GS 457 Query: 1397 LEPQLPRSPPGT-----------AETEPG-----RAASPPTLESSSLFPDLPVDRFDPPL 1440 PQ R PG + EPG PP E P P Sbjct: 458 TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP 517 Query: 1441 YGSLSANRDSGLPFACADPPQKTVPSD--PPYPSFLLLEEVSPMLPSHFPDLSGGKVLS- 1497 G A + G P + P K + P S + P P P L G + L+ Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGE-PGLPGARGLTG 576 Query: 1498 --KTCPPERTVVPGAAPSLPGK-GSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTR 1554 PE + P AP G+ G S+ + L K + Sbjct: 577 NPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPG-------------SMGLPGPKGSS 623 Query: 1555 GAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAES 1614 G P + EA + G P QR P +D VG E E Sbjct: 624 GDPGKPGEAGNAG---------VPGQR-----GAPGKDG-EVGPSGPVGPPGLAGERGEQ 668 Query: 1615 AVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGA 1674 QG PG P PG + D + P PRG + P ++ Sbjct: 669 GPPGPTGFQGLPGPPGPPGEGGKPGDQGV----PGDPGAVGPLGPRGERGN--PGERGEP 722 Query: 1675 SKTGL---------------------CQAEGDSRPPQDVCLPEP---SKQPGPQLDAGSL 1710 TGL GD+ PP +P + PGP+ D G + Sbjct: 723 GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI 782 Query: 1711 AKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQP-HRGAPAPEAF- 1768 ++ A D R LP G L PG A +G P P Sbjct: 783 -------------GEKGAEGTAGNDGARGLP-----GPLGPPGPAGPTGEKGEPGPRGLV 824 Query: 1769 GSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNE 1828 G P P +G+ P GA QG G+ G P G PG +G+ Sbjct: 825 GPPGSRGNP--GSRGENGPT-------GAVGFAGPQGPD-GQPGVKGEP--GEPGQKGDA 872 Query: 1829 FAPA--GASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDP----ALSPPIRQLQLPGP 1882 +P G + P G P V R +Q P ++ PGP Sbjct: 873 GSPGPQGLAGSPGPHG----------PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGP 922 Query: 1883 GVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAV 1942 A G LG P + P GL G G+V G PGG P Sbjct: 923 AGAPGPAGPLG---------EPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGE 973 Query: 1943 AGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS--PGGTDNHASVNASPKTALTG 2000 G DG G G + G Q + E G+ PG V + T G Sbjct: 974 DGQP---GPDGPPGPAGTTGQRGIVGMPGQ-RGERGMPGLPGPAGTPGKVGPTGATGDKG 1029 Query: 2001 PTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERAS 2060 P G V GS + P + +P R+ A+ G G P Sbjct: 1030 P-PGPV---GPPGSNGPVGEPGPEGPAGNDGTPGRDG-AVGERGDRGDPGPAG-LPGSQG 1083 Query: 2061 SPGLNKPLLATGDSPAPSVGDLAACAP-SPTSAAHMPCSLGPL-PREDPLTSPSRAQGGL 2118 +PG P+ A GD A GD + P P A GP PR D R G Sbjct: 1084 APGTPGPVGAPGD--AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQ 1141 Query: 2119 GGQ--LPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDS-----PVAPPSL 2171 G PPGP + P +G E + P+ PP + Sbjct: 1142 KGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGV 1201 Query: 2172 TTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVT 2209 S + AG EG P E PPG +T Sbjct: 1202 RGSVGE-----AG----PEGPPGEPGPPGPPGPPGHLT 1230 Score = 44.3 bits (103), Expect = 0.002 Identities = 98/382 (25%), Positives = 121/382 (31%), Gaps = 76/382 (19%) Query: 3504 DPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCAL----DGALERPENEASPGSP 3559 DPVT P C + S + P + F +G+ L G RP PGS Sbjct: 84 DPVTPPGECCPVCS---QTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQ 140 Query: 3560 GPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKE 3619 GP ++ P G RPG RG P G+ PG G P Sbjct: 141 GPRGERG-PKG----RPGPRG--------PQGIDGEPGVPGQPGAPGPPGHP-------- 179 Query: 3620 KEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA 3679 S GP G SA + S P PV PR G Sbjct: 180 ---------SHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSV--GPVGPRGPQG--- 225 Query: 3680 PGELARGTENGMKPATPKAKPG-PSSQG----SGSPRPGTKTGGGSQPQPASGQLQSETA 3734 +G + G P P +PG P G G P K G +P + A Sbjct: 226 ----LQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFA 281 Query: 3735 TTPAKPSFPSRSPAPERLPARAQAKSCTKGPR-EAGEQGPHGSLG-PKEKGESSTKRKKG 3792 +P FP P KG R G +GP G +G P KGE+ G Sbjct: 282 GSPGARGFPGAPGLPG-----------LKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMG 330 Query: 3793 QVPGPARSESV-GSFGRAPSAPDKPPRTPRKQATPSRVLPTKPK--PNSQNKPRPPPSEQ 3849 + GP + G GR P P P + P P P S P P Sbjct: 331 AM-GPLGPRGMPGERGRL--GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP---G 384 Query: 3850 RKAEPGHTQRKDRLGKAFPQGR 3871 K E G T + G PQG+ Sbjct: 385 MKGEAGPTGAR---GPEGPQGQ 403 Score = 39.3 bits (90), Expect = 0.078 Identities = 94/391 (24%), Positives = 126/391 (32%), Gaps = 75/391 (19%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDR--------PPPRGSSPILSEGSLPA 3479 PG PG K E P P PGP P RG + LP Sbjct: 962 PGGPGDKGDPGEDGQPG-------PDGPPGPAGTTGQRGIVGMPGQRGERGM---PGLPG 1011 Query: 3480 LLHLCSEVAPSTT---KGWPETLERPVD--PVTHPIRGCELPSNHQECPPPSLSPFPAAL 3534 +V P+ KG P + P PV P G E P+ + P Sbjct: 1012 PAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEP--GPEGPAGNDGTPGRD------GA 1063 Query: 3535 ADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAE-GKRAPL--- 3590 RGD G P ++ +PG+PG P+GA PG GQ + G R P+ Sbjct: 1064 VGERGDRGDPGPAGLPGSQGAPGTPG-------PVGA----PGDAGQRGDPGSRGPIGPP 1112 Query: 3591 VFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQS 3650 +GKR PG +G P + DH + ++ + G RG P G Sbjct: 1113 GRAGKRGLPGPQG---PRGDKGDHGDRGDR--------GQKGHRGFTGLQGLPGPPG--- 1158 Query: 3651 SSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPG-PSSQGSGS 3709 + ++ +A P P PR G + P G E P P PG S G Sbjct: 1159 PNGEQGSAGIPG-----PFGPRGPPGPVGPS----GKEGNPGPLGPIGPPGVRGSVGEAG 1209 Query: 3710 PRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAG 3769 P G P G L + P PE +A K Sbjct: 1210 PEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNK-----T 1264 Query: 3770 EQGPHGSLGPKEKGESSTKRKKGQVPGPARS 3800 + G H +L + + G PAR+ Sbjct: 1265 DPGVHATLKSLSSQIETMRSPDGSKKHPART 1295 Score = 38.9 bits (89), Expect = 0.10 Identities = 29/96 (30%), Positives = 35/96 (36%), Gaps = 16/96 (16%) Query: 3206 PAPKHHRGKRSAGKAAGSPG--DPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSA 3263 P P GK G PG P G GE + +PGER +P P Sbjct: 683 PGPPGEGGKPGDQGVPGDPGAVGPLGPRGE--RGNPGERGEPGITGLPGEK--------- 731 Query: 3264 SATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299 +A P P+ +P PS P G P LQ P Sbjct: 732 ---GMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP 764 Score = 35.8 bits (81), Expect = 0.86 Identities = 71/294 (24%), Positives = 84/294 (28%), Gaps = 41/294 (13%) Query: 1684 GDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLP-- 1741 GD P + P P PGP G + Q E + LP Sbjct: 966 GDKGDPGEDGQPGPDGPPGPAGTTGQ-------------RGIVGMPGQRGERGMPGLPGP 1012 Query: 1742 CEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSH 1801 G P T D+ G P P P+ DG P D GA Sbjct: 1013 AGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD-----GAVGER 1067 Query: 1802 AAQGHS--AGRAGGHLHP----TAGRPGFEGNEFAPAGASSLTAP-RGREAWLVPVPSPA 1854 +G AG G P G PG G P + P R + L P Sbjct: 1068 GDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPR 1127 Query: 1855 CVSNTHPSRRSQDPALSPPIRQLQ-LPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLE 1913 H R + LQ LPGP + G G+ P V PSG E Sbjct: 1128 GDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKE 1187 Query: 1914 GGT----------VEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEAD--GHW 1955 G V G GP +G PG P GH D GH+ Sbjct: 1188 GNPGPLGPIGPPGVRGSVGEAGP-EGPPGEPGPPGPPGPPGHLTAALGDIMGHY 1240 Score = 35.0 bits (79), Expect = 1.5 Identities = 36/133 (27%), Positives = 46/133 (34%), Gaps = 37/133 (27%) Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRG---KRSAGKAAGS--------------PGDPWG 3229 P GL+G + + P PK RG ++ A AG+ P P G Sbjct: 757 PPGLQGMPGERGIAGT---PGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTG 813 Query: 3230 QEGEAKKDS----PGERAKPRARST-----------PSNPDG--AATPDSASATALADAG 3272 ++GE PG R P +R P PDG + DAG Sbjct: 814 EKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAG 873 Query: 3273 SPGPPRTTPSPSP 3285 SPGP SP P Sbjct: 874 SPGPQGLAGSPGP 886 Score = 34.3 bits (77), Expect = 2.5 Identities = 49/193 (25%), Positives = 61/193 (31%), Gaps = 20/193 (10%) Query: 3692 KPATPKAKPGPSSQG-SGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPE 3750 +P P PS G G RP + G + G S+ P P P+ Sbjct: 169 QPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLG---SQVGLMPGSVG-PVGPRGPQ 224 Query: 3751 RLPARAQAKSCTKGPREAGEQGPHGSLG----------PKEKGESSTKRKKGQVPGPARS 3800 L + T P E G+ GP G +G P E GE G+V G A S Sbjct: 225 GLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEV-GFAGS 283 Query: 3801 ESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEP-GHTQR 3859 F AP P K + P + P P P G Sbjct: 284 PGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGE 343 Query: 3860 KDRLGKAFPQGRP 3872 + RLG PQG P Sbjct: 344 RGRLG---PQGAP 353 Score = 34.3 bits (77), Expect = 2.5 Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 9/74 (12%) Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDS--A 3263 P PK +G+R GS G P G +G+ + PGE P AR NP G P+ Sbjct: 536 PGPKGAQGERGP---VGSSG-PKGSQGDPGR--PGEPGLPGARGLTGNP-GVQGPEGKLG 588 Query: 3264 SATALADAGSPGPP 3277 A + G PGPP Sbjct: 589 PLGAPGEDGRPGPP 602 Score = 32.7 bits (73), Expect = 7.3 Identities = 67/264 (25%), Positives = 85/264 (32%), Gaps = 62/264 (23%) Query: 2633 GSRPSPAMASYAASPSHCLSVEGGPEADGEQPPR--LATLGPGVMEGAAETDQEALCAGE 2690 G +P +A SP G P G + R GP GA + EA G Sbjct: 270 GRNGNPGEVGFAGSPG-ARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGP 328 Query: 2691 TGAQKPPGDRMLCPGRMDGAALGEQPT-GQKGASARGFWG-PRETKALGVCKESG----- 2743 GA P G R + PG + LG Q GQ+GA G G P LG+ SG Sbjct: 329 MGAMGPLGPRGM-PG--ERGRLGPQGAPGQRGA--HGMPGKPGPMGPLGIPGSSGFPGNP 383 Query: 2744 ---SEPAEDSSRAHS-----RSEEG-------------VWEENTPPL-GPLGFPETSSSP 2781 E +R R E G + + TP GP G P TS P Sbjct: 384 GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPP 443 Query: 2782 AD-----------STTSSCLQGLPDNPDTQG--------------GVQGPEGPTPDASGS 2816 ST ++G P +P G G+QGP GP + Sbjct: 444 GSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR 503 Query: 2817 SAKDPPSLFDDEVSFSQLFPPGGR 2840 + P + PG R Sbjct: 504 GPRGDPGTVGPPGPVGERGAPGNR 527 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 90.9 bits (224), Expect = 2e-17 Identities = 255/1046 (24%), Positives = 328/1046 (31%), Gaps = 188/1046 (17%) Query: 1 MPG-ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED--NTPATRTTKGAREAGGQAQA 57 +PG + P+G P T Q + PG P P L P + G + + G Sbjct: 462 IPGVDGPKGEPGLLCT---QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518 Query: 58 MELPEAQPRQARDGELKPPSLRGQA-----PSSTPGKRGSP--QTPPGRSPLQAPSRLAG 110 LP G+ P L+G+ P G G P + PGR L G Sbjct: 519 TGLPGFPGFPGAQGD---PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575 Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGP-GTGAPLRPGLPRT 169 +G P + L ++ + P +P P P GP G G PGL T Sbjct: 576 -VKGLPGPKGELALSGEKGDQGPPGDPGSPGS-----PGPAGPAGPPGYGPQGEPGLQGT 629 Query: 170 EAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQ--PGSYPEY 227 + P A PP S S TP P PGPP G Q PG Sbjct: 630 QGVPGAPG---------PPGEAGPRGELSVS-TPVPGPPGPPGPPGHPGPQGPPGIPGSL 679 Query: 228 QASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSR--PGGSPR-GVSFQFPFPALHGA 283 G P P E PG F PP PKG + PG G + P L G Sbjct: 680 GKCGDPGLPGPDGEPGIPGIGFPGPPG-----PKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQP 342 P A GP F +G E P P LP P L +G P Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 343 GGLNRHSDLSGALSSPGAAHSAPR-----PFSDSLH-------KSLTKILPERPPSAQDG 390 G G PG PR P + L K+ K P P + G Sbjct: 795 G----QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850 Query: 391 LGSTRGPPS---------SLPQRHFPGQA--------------YRASGVDTSPGPPDT-- 425 G P L QR +PG G PGPP Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910 Query: 426 ---ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPL 482 + +PG P + Q P A G P + S + PG L A Sbjct: 911 TPGQRGSPGIPGVK-GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG----LKGFAGN 965 Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK--------- 533 P + P G++ L LP PAG P G +G LG+ G P + Sbjct: 966 PGEKG-NRGVPGMPGLKGLKGLPGPAGPP----GPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 534 -LPAVRSSQG--------GSPALFTYNGMTDPGAQPLFFGVAQP-QVSPHGTPSLPPPRV 583 +P + +G G P L +G+ +P + +P P G P LP Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSS-PANPSSEESQ----LPGPLGPSAFFHPP 638 + P P AG + SP S P P + G LGP PP Sbjct: 1081 KKGEMGQ-PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 639 THPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVG 698 P GSP P + P PA G +G L P P P G Sbjct: 1140 GLPGFPGSPGPMGIRGD--------QGRDGIPGPA---GEKGETGLLRAPPGPRGNP--G 1186 Query: 699 RGGLQGFPRAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLL 756 G +G AP P P ++ A R + + F G + Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAG-------------PRGPTGIEGFPGPPGLPGAI 1233 Query: 757 LA-----RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811 + R G + SPG PG P PP + + G + H G A G Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871 L P L P P D + G++ + NP F+ Sbjct: 1294 LGAPGTPGL-----PGPRGDPGF-----------QGFPGVKGEKGNP----GFLGSIGPP 1333 Query: 872 EPSGPRGPSS--GHPLKSKAGVTPESKAPPPLPA-----ATPDPQTPRPGDRG-CPARGR 923 P GP+GP G P K P S PP P P P P PG+ G C RG+ Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP-PGNLGPCGPRGK 1392 Query: 924 PKTRSLGLAPTEADAPSQGRQQRRGK 949 P G T A +G + +G+ Sbjct: 1393 PGKD--GKPGTPGPAGEKGNKGSKGE 1416 Score = 86.7 bits (213), Expect = 4e-16 Identities = 353/1494 (23%), Positives = 441/1494 (29%), Gaps = 412/1494 (27%) Query: 184 FQEPPSSFTSTNYTSPSATPRPPAP----------GPPQSRGTS-----------PLQPG 222 F PP S +T P P P P G RG S P PG Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPG 112 Query: 223 SYPEYQASGADSWPPA-AENSFPG--ANFGVP--------------PAEPEPIPKGSR-- 263 + Y G + E FPG G P PA+ E I ++ Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172 Query: 264 PG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG-- 319 PG G+P P P G P P G GP P+G E +G Sbjct: 173 PGLPGAPGPQGLPGP-PGFPGPVGPPGPPGFFGFPGAMGP-----RGPKGHMGERVIGHK 226 Query: 320 --------TGPAYP----LPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAP 365 TGP P + T P +G+ G G G PG ++ + Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286 Query: 366 R--PFSDSLHKSLTKI-LPERPPSAQDGLGSTRGPPSSLPQRHFPGQ------------- 409 + P L K +P P S +G+ RG P + + GQ Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGS--EGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344 Query: 410 ----AYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP-YPTPPGGPLAATR---- 460 Y+ G + +PGP PGP AR PQ P+ P P PG R Sbjct: 345 EYYDTYQEKGDEGTPGP-------PGPRGARGPQ--GPSGPPGVPGSPGSSRPGLRGAPG 395 Query: 461 ------SMFFNGQP------SPGQRLC-----LPQSAPLPWPQ---VLPTARPSPHGME- 499 S G+P +PG C LP S P P V P HG+ Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455 Query: 500 -------------------MLSRLPFPAGGPEWQG-----------GSQGALGTAGKTPG 529 + ++ P+ G P G G QGA G G Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515 Query: 530 P-REKLPAVRSSQG--GSPALFTYNGMT-----------DPG--AQPLFFGVAQPQVSPH 573 P LP G G P L G T DPG QP G+ +P Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP- 574 Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPS 632 G LP P+ A E P G S SP + PA P Q PG G Sbjct: 575 GVKGLPGPKGELALSGEKGDQGP----PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630 Query: 633 AFFHPPTHPQETG--------SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQC 684 P P E G +P P P P P H P+ P G G Sbjct: 631 GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---- 686 Query: 685 LEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLA 744 P E G G+ GFP P P F + SL Sbjct: 687 -----LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG------------------- 721 Query: 745 AFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQ 804 K G PG PGLP P V G T G+ Sbjct: 722 -------------CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG------TPGFPGERG 762 Query: 805 AEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSF 864 G+ + LP L TP E L+G P Sbjct: 763 NSGEHGEIGLPGLPGLPGTPG-------------------NEGLDGPRGDPGQP------ 797 Query: 865 IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924 P G +GP G ++ G ++ P L Q R G G +G P Sbjct: 798 -------GPPGEQGP-PGRCIEGPRG----AQGLPGLNGL--KGQQGRRGKTG--PKGDP 841 Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984 L + + S G +G+ L ++ G G L P D Sbjct: 842 GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR-------------GYPGNPGILGPPGED 888 Query: 985 GL--------GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDP 1036 G+ PP P P T PG R P +P +R P K Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGT--PGQRGSPG--IPGVKG---------QRGTPGAKGE 935 Query: 1037 RKRKARGGAWGKELILKIVQQKNRLREYDFA-SESEEDEQPPPRGPGFRGRRGRGEKRKE 1095 + K G G I ++ K FA + E+ + P PG +G +G Sbjct: 936 QGDK---GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL------ 986 Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155 P P PR G G+ NP EP G R PG P + G Sbjct: 987 ------PGPAGPPGPR-------GDLGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 1156 AREGGPKCADRPSVAPKDPLQVPTNTE-TSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214 G P A RP + LQ SE TRP P T + P Sbjct: 1033 ---GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP-------TGDPGLPGD---- 1078 Query: 1215 EALRSPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272 GEMG PG L P P + G+P G PHG G+ Sbjct: 1079 -------MGKKGEMGQPGPPGHLGPAGPEGA---PGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 1273 LLGGPG-----------------GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPS 1315 LLG PG G + + PA + GE A P P Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP--- 1185 Query: 1316 VLSSKISSFGCDPAGFNRDPLGVP--VAKKGPQPYSSPHS----ELFLGPKDLAGCFLEE 1369 G A +R G P +KG + P E F GP L G + Sbjct: 1186 ---------GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236 Query: 1370 L---HPKPSARDAP-------PASSSCLCQDGEDAGSLEPQLPRSPPGTAET--EPGRAA 1417 P +R +P P S + G D GS+ P+ PPGTA PGR Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKG-DKGSMGHPGPKGPPGTAGDMGPPGRLG 1295 Query: 1418 SPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLP--FACADPPQKTVPSDPP 1469 +P T P LP R DP G + G P PP P PP Sbjct: 1296 APGT-------PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Score = 77.8 bits (190), Expect = 2e-13 Identities = 289/1237 (23%), Positives = 378/1237 (30%), Gaps = 221/1237 (17%) Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPIPKGS 262 PGPP + + P + + + D P + PG ++G P Sbjct: 238 PGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297 Query: 263 RPG-----GSP--RGVSFQFPFPALHGAS-TKPFPADVAGHAFTNGPLVFAFHQPQGAWP 314 +PG G P GV FP L G K D+ F + +Q +G Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG--- 354 Query: 315 EEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372 + GP P + PS P G PG + L GA PG S Sbjct: 355 -DEGTPGPPGPRGARGPQGPSGPPGVPGSPG--SSRPGLRGAPGWPGLKGSKG------- 404 Query: 373 HKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP 432 ER +D +G T G P PG PGPP + GP Sbjct: 405 ---------ERGRPGKDAMG-TPGSPGCAGSPGLPGSP-------GPPGPPGDIVFRKGP 447 Query: 433 PPAR-LP-QLWDPTAAPYPTPPGGP-LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489 P LP L P P G P L T+ + G P L +P Q Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL-----PAVRSSQG-- 542 + SP G + LP G P QG G G G+T P ++ P +R G Sbjct: 508 GLKGSP-GSPGNTGLPGFPGFPGAQG-DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565 Query: 543 ---GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH--GTPSLPPPRVVGASPSESPLPSPA 597 G P G+ P + G Q P G+P P P P P P Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625 Query: 598 TN-TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP--------- 647 T G + P + P S + +PGP GP PP HP G P Sbjct: 626 LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG---PPGHPGPQGPPGIPGSLGKC 682 Query: 648 ----FPSPEPPHSLPTHYQPEPA-----KAFPFPADGLGAEG------------------ 680 P P+ +P P P + FP LG G Sbjct: 683 GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742 Query: 681 ----AFQCLEETP-FPHEGPEVGRGGLQGFPRAPP-PYPTHHFSLSSASLD--------Q 726 A TP FP E G G G P P P + L D + Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802 Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL-----PSPPAAPR 781 C + R L + G R K G + PG PGL P +P Sbjct: 803 QGPPGRCIEGPRGAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPG 859 Query: 782 VPA-DAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFP-----LPASDLDME 835 +P G L G G+D + P P P P Sbjct: 860 IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919 Query: 836 DDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT--P 893 T G + NP S V D+ G +G + K GV P Sbjct: 920 IPGVKGQRGTPGAKGEQGDKGNPG-PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978 Query: 894 ESKAPP--PLPAATPDPQ-----TPRPGDRGCPARGRPKTR-SLGLAPTEADAPSQGRQQ 945 K P PA P P+ T PG+ G RG P + ++G+ ++ + G Sbjct: 979 GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Query: 946 RRGKQ----LKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQA 1001 R G+ + + D G +EG+ G G P + GL P ++ Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG------PTGDPGL---PGDMGKKGEMGQ 1087 Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061 PG P P A S LP + P G G + I K L Sbjct: 1088 PGPPGHLGPAGPEGAP-----GSPGSPGLPGKPGPH------GDLGFKGI------KGLL 1130 Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR-------GEKRKE--VELTQGPREDEPQKPR 1111 P GP G RG +GR GEK + + GPR + + Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190 Query: 1112 KAARQEAGGDGAP--------ANPEEPGGSR--PGPGRSPQARGPSRSLETGAAAREGGP 1161 K R G G P A P P G PGP P A P ++ G G P Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS------TEFTE 1215 AP P ++ + + S+ P P TA + P T Sbjct: 1251 G-------APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 1216 ALRSPPA-----ACAGEMG--------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH 1262 R P GE G PG + P+ PP R D GT K + P Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 1263 GSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297 G+ PG+ G GP G P K +PG Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400 Score = 69.7 bits (169), Expect = 5e-11 Identities = 281/1179 (23%), Positives = 364/1179 (30%), Gaps = 217/1179 (18%) Query: 65 PRQAR--DGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122 PR AR G PP + G SS PG RG+P P + R A G+P Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP--- 420 Query: 123 GIASSRTKPTLDETPENP-----------------QLEAAQLPEVDTPQG-PG---TGAP 161 G A S P P P L + +P VD P+G PG T P Sbjct: 421 GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP 480 Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP 221 PG P P G ++ + SP T P PG P ++G L+ Sbjct: 481 YIPGPPGLPGLPGLH--GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538 Query: 222 GSYPEYQASGADSWP--PAAENSFPGANF-----GVPPAEPEPIPKGSRPGGSPRGVSFQ 274 Q G P P PG G P + P PKG +G Q Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKG--DQ 595 Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSP 334 P P G+ P PA AG P G P+ G +P P P Sbjct: 596 GP-PGDPGSPGSPGPAGPAG--------------PPGYGPQGEPGLQGTQGVPGAPGP-- 638 Query: 335 LPCYQGQPGGLNRHSDLSGALSSPG-AAHSAPR---PFSDSLHKSLTKILPERPPSAQDG 390 P G G L+ + + G PG H P+ SL K LP P + G Sbjct: 639 -PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP--GPDGEPG 695 Query: 391 LGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY 448 + GPP + FPG G PG ++ PG P P L P Sbjct: 696 IPGIGFPGPPGPKGDQGFPG----TKGSLGCPG----KMGEPGLPGK--PGLPGAKGEPA 745 Query: 449 PTPPGGPLAATRSMFFNGQPS-PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP 507 PGGP G P PG+R HG L LP Sbjct: 746 VAMPGGP----------GTPGFPGER-----------------GNSGEHGEIGLPGLPGL 778 Query: 508 AGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGV 565 G P G G G G+ P E+ P R +G G+ L NG+ + Sbjct: 779 PGTP-GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR------ 831 Query: 566 AQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPS---- 619 + + P G P +P G S P + + G + P+ P NP Sbjct: 832 -RGKTGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQ-GEMGPLGQRGYPGNPGILGP 884 Query: 620 -SEESQL-----PGPLGPSAFFHPPTHPQETGSP-FPSPEPPHSLPTHYQPEPAKAFPFP 672 E+ + PG +GP P P + GSP P + P + K P P Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944 Query: 673 AD-----GLGAEGAFQCLEETPFPHEGPEV----GRGGLQGFP-RAPPPYPTHHFSLSS- 721 ++ G E + P V G GL+G P A PP P + Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004 Query: 722 ----------ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG-- 769 S+ + + + F GL G + PG Sbjct: 1005 PGEPGLRGIPGSMGNMGM-----PGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059 Query: 770 ---PPGLPSPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPF 825 PG P P P +P D G + G A EG + LP Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----- 1114 Query: 826 PLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPL 885 P P DL + L L + G P P G RG + Sbjct: 1115 PGPHGDLGFKGIKGL--LGPPGIRGPPGLPGFP----------GSPGPMGIRGDQGRDGI 1162 Query: 886 KSKAGVTPES--KAPPPLPAATPDPQTPRPGDRGCPA-RGRP-KTRSLGLAPTEADAPSQ 941 AG E+ PP P P Q + GDRG P G P + ++G A + Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221 Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL----GERPPPRPRRP 997 G G + + G GS G G G+ G P P+ P Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281 Query: 998 -----------RTQAPGSRADPAPR-VPRAAALP----EETRSSRRRRLPPRKDPRKRKA 1041 R APG+ P PR P P E+ + P P K Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGPKG 1340 Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGP-------GFRGRRGRGEKRK 1094 G G LKI+ E +P P GP G RG+ G+ K Sbjct: 1341 PPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400 Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGS 1133 T GP ++ K K AG DG P + G S Sbjct: 1401 ----TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDS 1435 Score = 69.3 bits (168), Expect = 7e-11 Identities = 200/845 (23%), Positives = 263/845 (31%), Gaps = 154/845 (18%) Query: 477 PQSAPLPWPQVLPTARPSPH-GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR---- 531 PQ LP VL A P+ G + G + + G +G G G +PG + Sbjct: 9 PQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPG-SPGQKGFTG 67 Query: 532 -EKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASP 588 E LP + +G G P L G+ P F G +P T V G S Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127 Query: 589 SESP-----LPSPATNTAGSTCSSLSPMSSSPANPSSEESQ------LPGPLGPSAFFHP 637 S+ LP + L +PA E LPG GP P Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187 Query: 638 PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEV 697 P P G P P F FP +G G + E H+G E Sbjct: 188 PGFPGPVG----------------PPGPPGFFGFPG-AMGPRGPKGHMGERVIGHKG-ER 229 Query: 698 GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLL 757 G GL G P PP V++T D N + L Sbjct: 230 GVKGLTG-PPGPPG----------------TVIVTLTGPD-NRTDL-------------- 257 Query: 758 ARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817 + + G + + G PG P P P + G GD +GK Sbjct: 258 -KGEKGDKGAMGEPGPPGPSGLPGESYGSEKG---------APGDPGLQGK--------- 298 Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877 P P P S+ ++ + L+ E +G++ Q D P G R Sbjct: 299 PGKDGVP-GFPGSE-GVKGNRGFPGLMGE--DGIKGQK-------------GDIGPPGFR 341 Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPR--PGDRGCPARGRPKTRSLGLAPTE 935 GP+ + + G E PP P PQ P PG G P RP R G Sbjct: 342 GPTEYYDTYQEKG--DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR--GAPGWP 397 Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP--- 992 S+G + R GK + + G+ +GS G + G D + + PP Sbjct: 398 GLKGSKGERGRPGKDA------MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451 Query: 993 -------RPRRPRTQA----PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKA 1041 P P PG P +P LP + +P R+ K Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511 Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP-----PRGPGFRGRRGRGEKRKEV 1096 G+ G + + E E QP P PG RG+ GR + + Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGR-KGLDGI 570 Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAA 1156 T G + K A E G G P +P PG P P GP E G Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG--EPGLQG 628 Query: 1157 REGGPKCADRPSVA-PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215 +G P P A P+ L V T P P P P + Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVST---------PVPGPPGPPGPPGHPGPQGPPGIPGSL 679 Query: 1216 ALRSPPAACA--GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273 P GE G PG+ P PP + D G P GSL G PG L Sbjct: 680 GKCGDPGLPGPDGEPGI-PGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737 Query: 1274 LGGPG 1278 G G Sbjct: 738 PGAKG 742 Score = 67.4 bits (163), Expect = 3e-10 Identities = 285/1227 (23%), Positives = 374/1227 (30%), Gaps = 204/1227 (16%) Query: 1682 AEGDSRPPQDVCLPEPS--KQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739 A G+ PP LP S + G D G K D FP E R Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP-------GSEGVKGNRG 318 Query: 1740 LPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASP 1799 P G + E G Q +G P F P + +G P P G Sbjct: 319 FP-----GLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-----PPGPRG 366 Query: 1800 SHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVS 1857 + QG S G G P + RPG G P G+ G++A P SP C Sbjct: 367 ARGPQGPS-GPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP-GSPGCAG 424 Query: 1858 NTHPSRRSQDPALSPP------------------IRQLQLPGPGVAKSKDGILGLQELTP 1899 + P PP + +PG K + G+L Q P Sbjct: 425 S--PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ--CP 480 Query: 1900 AAQSPPRV-NPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958 PP + GL G G+ +GSPG T LP G A G GL Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP---GAQGDPGLK 537 Query: 1959 GQAEKTQGQGTANQLQPENGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAA 2017 G+ +T LQPE V PG + G T G L KG A Sbjct: 538 GEKGET--------LQPEGQVGVPGDPGLRGQPGRKGLDGIPG-TPGVKGLPGPKGELAL 588 Query: 2018 MSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077 + + P P SP A +G G P+ PGL G P Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPA-------GPAGPPGYGPQ--GEPGLQGTQGVPGAPGPP 639 Query: 2078 SV----GDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133 G+L+ P P P GP P P G LG P P G Sbjct: 640 GEAGPRGELSVSTPVPGP----PGPPGPPGHPGP-QGPPGIPGSLG--KCGDPGLPGPDG 692 Query: 2134 PQQLLACSPAWAPLEEAD-GVQATTDT----GAEDSPVAP--PSLTTSPCDPKEALAGCL 2186 + P + D G T + G P P P L + +P A+ G Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-- 750 Query: 2187 LQGEGS---PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243 G G+ P E +S G + TP + L P R + P P Sbjct: 751 --GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGP 805 Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302 P P A GL+ G + Q G RG GP +G P DR + S Sbjct: 806 PGRCIEGPRGAQGLPGLN----GLKGQQGRRGKTGP----KGDPGIPGLDRSGFPGETGS 857 Query: 2303 PSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK--EPEDPGTPETGRS 2360 P G P P L G D + G G P +PGTP G+ Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP--GQR 915 Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420 G+ +P V G+ P + +P + +G+P Sbjct: 916 GSPGIPGVK--------GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP--------GL 959 Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480 +G+ P N R PG+ K K P P P P Sbjct: 960 KGFAGNPGEKGN---------------------RGVPGMPGLKGLKGLPGPAGPPGPRGD 998 Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP--PPAQGSKEVLRAPG 2538 P EP + P + + G + + G P +P P G + PG Sbjct: 999 LGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057 Query: 2539 SPHSQQLHPPSPT-----EHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593 + PP PT ++ K +P P L P E G Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP----PGHLGPAGPEGAPGSPGSPGLPG 1113 Query: 2594 DSPSHSEGKSNKKRGKLRGRRLREESILP----------VSADVISDGRGSRPSPA---- 2639 H + +G L +R LP + D GR P PA Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD---QGRDGIPGPAGEKG 1170 Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698 A P G P A G + R A PG + G +A G TG + PG Sbjct: 1171 ETGLLRAPP----GPRGNPGAQGAKGDRGAPGFPG-LPGRKGAMGDAGPRGPTGIEGFPG 1225 Query: 2699 DRMLCPGRMDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757 L + G P G +G+ A G GP + +G+ + GS + Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS-----MGHPGPKG 1280 Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP------DNPDTQGGVQGPEGPTP 2811 G + PP G LG P T P QG P NP G + GP GP Sbjct: 1281 PPGTAGDMGPP-GRLGAPGTPGLPGPRGDPG-FQGFPGVKGEKGNPGFLGSI-GPPGPI- 1336 Query: 2812 DASGSSAKDPPSLFDDEVSFSQLFPPG 2838 K PP + D + + PG Sbjct: 1337 -----GPKGPPGVRGDPGTLKIISLPG 1358 Score = 65.1 bits (157), Expect = 1e-09 Identities = 176/713 (24%), Positives = 227/713 (31%), Gaps = 137/713 (19%) Query: 28 GHPSQP-PLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSST 86 G P QP P + P R +G R A G L Q R+ + G P + G S Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851 Query: 87 PGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQ 146 PG+ GSP P + + + G P ILG P ++ Sbjct: 852 PGETGSPGIPGHQGEMGPLGQ-----RGYPGNPGILG-------PPGEDGVIGMMGFPGA 899 Query: 147 LPEVDTPQGPGT----GAPLRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSA 201 + P PGT G+P PG+ P A+ E G S + P Sbjct: 900 IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL 959 Query: 202 TPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKG 261 PG +RG P PG G P A P + G EP +G Sbjct: 960 KGFAGNPGEKGNRGV-PGMPG------LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012 Query: 262 --------SRPGGSPRGVSFQFP-------FPALHG-----------ASTKPFPADVAGH 295 PG + + FP P +HG T+P P G Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGD 1072 Query: 296 AFTNGPL----VFAFHQPQG----AWPEEAVGTGPAYPLPTQPAPSPLPCYQG-----QP 342 G + P G A PE A G+ + LP +P P ++G P Sbjct: 1073 PGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP 1132 Query: 343 GGLNRHSDLSGALSSPG--------AAHSAPRPFSDSLHKSLTKIL--PERPPSAQDGLG 392 G+ L G SPG P P + L + P P AQ G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 393 STRGPPSSLPQRHFPGQAYRASGV-DTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTP 451 RG P FPG R + D P P PGPP LP P P Sbjct: 1193 D-RGAPG------FPGLPGRKGAMGDAGPRGPTGIEGFPGPP--GLPGAIIPGQTGNRGP 1243 Query: 452 PGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP 511 PG + SPG AP P P P G ++ G Sbjct: 1244 PG------------SRGSPG--------APGP---------PGPPGSHVI--------GI 1266 Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571 + GS G G G + P R G+P L G DPG Q F GV + + Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG--DPGFQG-FPGVKGEKGN 1323 Query: 572 PHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSE-ESQLPGP-- 628 P S+ PP +G P T S S P +P P + E PGP Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP-PGTPGEPGMQGEPGPPGPPG 1382 Query: 629 -LGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEG 680 LGP P + G+P P+ E + + +K P PA G G Sbjct: 1383 NLGPCGPRGKPGKDGKPGTPGPAGEKGN--------KGSKGEPGPAGSDGLPG 1427 Score = 58.9 bits (141), Expect = 9e-08 Identities = 116/476 (24%), Positives = 150/476 (31%), Gaps = 78/476 (16%) Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488 G PG+K +P + +PG A PG PRG P L + + Sbjct: 964 GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG-----PRGDLGSTGNPGEPGLRGIPGSMG 1018 Query: 3489 ----PST-----TKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRG 3539 P + T G+P RP P H ++G + + E P P P G Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPG-PPGPTGDPGLPG 1077 Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG----QDAEGKRAPLVFSG 3594 D G + +P G GP P LP +PG G + +G P G Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137 Query: 3595 KRRAPGARGRCAPDHFQEDHLLQ-----KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649 PG G P + D ++ + + + GPRG G Q Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN---------PGAQ 1188 Query: 3650 SSSKDRSAASTPS----KALKFPVHPRKAVGSLA-------PGELARGTENGMKPATPKA 3698 + DR A P K PR G PG + G P + Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248 Query: 3699 KPG-PSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756 PG P G GS G K GS P P P + P R Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPG--------------PKGPPGTAGDMGPPGRL 1294 Query: 3757 QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP 3816 A P G GP G P +G K +KG PG +GS G P P P Sbjct: 1295 GA------PGTPGLPGPRGD--PGFQGFPGVKGEKGN-PG-----FLGSIG--PPGPIGP 1338 Query: 3817 PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 P + P L P S P P + EPG LG P+G+P Sbjct: 1339 KGPPGVRGDPG-TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Score = 46.2 bits (108), Expect = 6e-04 Identities = 119/452 (26%), Positives = 148/452 (32%), Gaps = 83/452 (18%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG+PGQK LP + PG P GS + LP Sbjct: 57 PGSPGQKGFTGPEGLPGPQGPKGFPG--------LPGLTGSKGVRGISGLPGF------- 101 Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP--PPSLS----PFPAALADGRGDC 3541 S + G P T + GC Q P P +L P A L +G Sbjct: 102 --SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 3542 AL--DGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAP 3599 A D L+ + PG+PGP Q LP P P G P F G P Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGP-------VGPPGPPGFFG---FP 206 Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP---AGCQSSSKDRS 3656 GA G P + ++ + E + GP GT + T P + D+ Sbjct: 207 GAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIV-TLTGPDNRTDLKGEKGDKG 265 Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG-------PSSQGS 3707 A P P P S PGE + G+E G P P + KPG P S+G Sbjct: 266 AMGEPG-----PPGP-----SGLPGE-SYGSEKG-APGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 3708 GSPR--PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765 R PG G + Q G + P + + E P GP Sbjct: 314 KGNRGFPGLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-------PPGP 364 Query: 3766 REA-GEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824 R A G QGP G G SS +G P S G GR P +P Sbjct: 365 RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAG 424 Query: 3825 TPSRVLPTKPKPNSQNKPRPPPS-EQRKAEPG 3855 +P LP P P P PP RK PG Sbjct: 425 SPG--LPGSPGP-----PGPPGDIVFRKGPPG 449 Score = 44.3 bits (103), Expect = 0.002 Identities = 115/447 (25%), Positives = 136/447 (30%), Gaps = 89/447 (19%) Query: 3414 RGGRQPFAFRG-VRRPGAPGQKARALEGTLP--SKRRRVAMPGSAPGPGEDRPPPRGSSP 3470 +G R F G RPG PG + P S+ R PG PG P G Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG--LPGDMGKKG 1083 Query: 3471 ILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP------IRGCELPSNHQECPP 3524 + + P L P G P + P P H I+G P + P Sbjct: 1084 EMGQPGPPGHL---GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--P 1138 Query: 3525 PSLSPFPAALADG--RGDCALDG----ALERPEN---------EASPGSPGPLLQQALPL 3569 P L FP + RGD DG A E+ E +PG+ G + P Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198 Query: 3570 GASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628 LP R GA G G R P G PG G P Sbjct: 1199 FPGLPGRKGAMGD--AGPRGPTGIEGFPGPPGLPGAIIPGQ------------------T 1238 Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGT 3687 GP G+ A P G S S P P G + P G L Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA-- 1296 Query: 3688 ENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR-- 3745 P TP PGP PG K G + P G L S P P P Sbjct: 1297 -----PGTP-GLPGPRGDPGFQGFPGVK---GEKGNP--GFLGSIGPPGPIGPKGPPGVR 1345 Query: 3746 -------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792 SP P P + E G GP G+LGP K K Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQG------EPGPPGPPGNLGPCGPRGKPGKDGKP 1399 Query: 3793 QVPGPARSE-SVGSFGR-APSAPDKPP 3817 PGPA + + GS G P+ D P Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGSDGLP 1426 Score = 40.8 bits (94), Expect = 0.027 Identities = 117/495 (23%), Positives = 146/495 (29%), Gaps = 74/495 (14%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG PG K LP + +A+ G G P SP + + P E Sbjct: 571 PGTPGVKG------LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP 624 Query: 3488 APSTTKGWPETLERPVDP-------VTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG 3539 T+G P P + V+ P+ G P P P P P +L G Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL----G 680 Query: 3540 DCALDGALERPENEAS------PGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF 3592 C D L P+ E PG PGP Q P SL PG G+ Sbjct: 681 KCG-DPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG--------L 731 Query: 3593 SGKRRAPGARGR--CAPDHFQEDHLLQKEKEVSSSH----MVSEGGPRGTFHKGSATKPA 3646 GK PGA+G A E+ S H + G GT P Sbjct: 732 PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791 Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT-PKAKPG---- 3701 G P + ++ PR A G PG + G + T PK PG Sbjct: 792 GDPGQPGPPGEQGPPGRCIE---GPRGAQG--LPGLNGLKGQQGRRGKTGPKGDPGIPGL 846 Query: 3702 --------------PSSQGSGSP--RPGTKTGGGSQPQPAS----GQLQSETATTPAKPS 3741 P QG P + G G P G + A P P Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906 Query: 3742 FPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPGP 3797 +P P K P GEQG G+ GP E G+ KG P Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966 Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHT 3857 + G G K P P L + P P S PG Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Query: 3858 QRKDRLGKAFPQGRP 3872 ++ LG GRP Sbjct: 1027 GKRGTLGFPGRAGRP 1041 Score = 37.7 bits (86), Expect = 0.23 Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 9/115 (7%) Query: 3176 RGQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAK 3235 RGQ R D G+ G+ V L E A +G + GSPG P G G A Sbjct: 559 RGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAG 614 Query: 3236 KDSPGERAKPRARSTPS-----NPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285 G + +P + T P G A P + + G PGPP P P Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669 Score = 35.0 bits (79), Expect = 1.5 Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%) Query: 3183 LGDLPG-----GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKD 3237 L LPG G+ G A L S P G A G PG G++GE + Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK-GEKGETLQP 546 Query: 3238 S--------PGERAKPRARST---PSNPDGAATPDSASATALA----DAGSPGPPRTTPS 3282 PG R +P + P P P AL+ D G PG P + S Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 3283 PSPDPWAG-------GEPLLQAT 3298 P P AG GEP LQ T Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGT 629 Score = 32.3 bits (72), Expect = 9.5 Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 28/116 (24%) Query: 3205 EPAPKHHRGK--RSAGKAAGSPGDPWGQEGEAKKDS----PGERAKPRARSTPS------ 3252 EP P G S G G+PGDP G +G+ KD PG R P Sbjct: 269 EPGPPGPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327 Query: 3253 --------NPDGAATPDSASAT--ALADAGSPGPP-----RTTPSPSPDPWAGGEP 3293 P G P T D G+PGPP R PS P G P Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 90.9 bits (224), Expect = 2e-17 Identities = 255/1046 (24%), Positives = 328/1046 (31%), Gaps = 188/1046 (17%) Query: 1 MPG-ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED--NTPATRTTKGAREAGGQAQA 57 +PG + P+G P T Q + PG P P L P + G + + G Sbjct: 462 IPGVDGPKGEPGLLCT---QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518 Query: 58 MELPEAQPRQARDGELKPPSLRGQA-----PSSTPGKRGSP--QTPPGRSPLQAPSRLAG 110 LP G+ P L+G+ P G G P + PGR L G Sbjct: 519 TGLPGFPGFPGAQGD---PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575 Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGP-GTGAPLRPGLPRT 169 +G P + L ++ + P +P P P GP G G PGL T Sbjct: 576 -VKGLPGPKGELALSGEKGDQGPPGDPGSPGS-----PGPAGPAGPPGYGPQGEPGLQGT 629 Query: 170 EAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQ--PGSYPEY 227 + P A PP S S TP P PGPP G Q PG Sbjct: 630 QGVPGAPG---------PPGEAGPRGELSVS-TPVPGPPGPPGPPGHPGPQGPPGIPGSL 679 Query: 228 QASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSR--PGGSPR-GVSFQFPFPALHGA 283 G P P E PG F PP PKG + PG G + P L G Sbjct: 680 GKCGDPGLPGPDGEPGIPGIGFPGPPG-----PKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQP 342 P A GP F +G E P P LP P L +G P Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 343 GGLNRHSDLSGALSSPGAAHSAPR-----PFSDSLH-------KSLTKILPERPPSAQDG 390 G G PG PR P + L K+ K P P + G Sbjct: 795 G----QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850 Query: 391 LGSTRGPPS---------SLPQRHFPGQA--------------YRASGVDTSPGPPDT-- 425 G P L QR +PG G PGPP Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910 Query: 426 ---ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPL 482 + +PG P + Q P A G P + S + PG L A Sbjct: 911 TPGQRGSPGIPGVK-GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG----LKGFAGN 965 Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK--------- 533 P + P G++ L LP PAG P G +G LG+ G P + Sbjct: 966 PGEKG-NRGVPGMPGLKGLKGLPGPAGPP----GPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 534 -LPAVRSSQG--------GSPALFTYNGMTDPGAQPLFFGVAQP-QVSPHGTPSLPPPRV 583 +P + +G G P L +G+ +P + +P P G P LP Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSS-PANPSSEESQ----LPGPLGPSAFFHPP 638 + P P AG + SP S P P + G LGP PP Sbjct: 1081 KKGEMGQ-PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 639 THPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVG 698 P GSP P + P PA G +G L P P P G Sbjct: 1140 GLPGFPGSPGPMGIRGD--------QGRDGIPGPA---GEKGETGLLRAPPGPRGNP--G 1186 Query: 699 RGGLQGFPRAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLL 756 G +G AP P P ++ A R + + F G + Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAG-------------PRGPTGIEGFPGPPGLPGAI 1233 Query: 757 LA-----RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811 + R G + SPG PG P PP + + G + H G A G Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871 L P L P P D + G++ + NP F+ Sbjct: 1294 LGAPGTPGL-----PGPRGDPGF-----------QGFPGVKGEKGNP----GFLGSIGPP 1333 Query: 872 EPSGPRGPSS--GHPLKSKAGVTPESKAPPPLPA-----ATPDPQTPRPGDRG-CPARGR 923 P GP+GP G P K P S PP P P P P PG+ G C RG+ Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP-PGNLGPCGPRGK 1392 Query: 924 PKTRSLGLAPTEADAPSQGRQQRRGK 949 P G T A +G + +G+ Sbjct: 1393 PGKD--GKPGTPGPAGEKGNKGSKGE 1416 Score = 86.7 bits (213), Expect = 4e-16 Identities = 353/1494 (23%), Positives = 441/1494 (29%), Gaps = 412/1494 (27%) Query: 184 FQEPPSSFTSTNYTSPSATPRPPAP----------GPPQSRGTS-----------PLQPG 222 F PP S +T P P P P G RG S P PG Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPG 112 Query: 223 SYPEYQASGADSWPPA-AENSFPG--ANFGVP--------------PAEPEPIPKGSR-- 263 + Y G + E FPG G P PA+ E I ++ Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172 Query: 264 PG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG-- 319 PG G+P P P G P P G GP P+G E +G Sbjct: 173 PGLPGAPGPQGLPGP-PGFPGPVGPPGPPGFFGFPGAMGP-----RGPKGHMGERVIGHK 226 Query: 320 --------TGPAYP----LPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAP 365 TGP P + T P +G+ G G G PG ++ + Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286 Query: 366 R--PFSDSLHKSLTKI-LPERPPSAQDGLGSTRGPPSSLPQRHFPGQ------------- 409 + P L K +P P S +G+ RG P + + GQ Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGS--EGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344 Query: 410 ----AYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP-YPTPPGGPLAATR---- 460 Y+ G + +PGP PGP AR PQ P+ P P PG R Sbjct: 345 EYYDTYQEKGDEGTPGP-------PGPRGARGPQ--GPSGPPGVPGSPGSSRPGLRGAPG 395 Query: 461 ------SMFFNGQP------SPGQRLC-----LPQSAPLPWPQ---VLPTARPSPHGME- 499 S G+P +PG C LP S P P V P HG+ Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455 Query: 500 -------------------MLSRLPFPAGGPEWQG-----------GSQGALGTAGKTPG 529 + ++ P+ G P G G QGA G G Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515 Query: 530 P-REKLPAVRSSQG--GSPALFTYNGMT-----------DPG--AQPLFFGVAQPQVSPH 573 P LP G G P L G T DPG QP G+ +P Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP- 574 Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPS 632 G LP P+ A E P G S SP + PA P Q PG G Sbjct: 575 GVKGLPGPKGELALSGEKGDQGP----PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630 Query: 633 AFFHPPTHPQETG--------SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQC 684 P P E G +P P P P P H P+ P G G Sbjct: 631 GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---- 686 Query: 685 LEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLA 744 P E G G+ GFP P P F + SL Sbjct: 687 -----LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG------------------- 721 Query: 745 AFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQ 804 K G PG PGLP P V G T G+ Sbjct: 722 -------------CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG------TPGFPGERG 762 Query: 805 AEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSF 864 G+ + LP L TP E L+G P Sbjct: 763 NSGEHGEIGLPGLPGLPGTPG-------------------NEGLDGPRGDPGQP------ 797 Query: 865 IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924 P G +GP G ++ G ++ P L Q R G G +G P Sbjct: 798 -------GPPGEQGP-PGRCIEGPRG----AQGLPGLNGL--KGQQGRRGKTG--PKGDP 841 Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984 L + + S G +G+ L ++ G G L P D Sbjct: 842 GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR-------------GYPGNPGILGPPGED 888 Query: 985 GL--------GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDP 1036 G+ PP P P T PG R P +P +R P K Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGT--PGQRGSPG--IPGVKG---------QRGTPGAKGE 935 Query: 1037 RKRKARGGAWGKELILKIVQQKNRLREYDFA-SESEEDEQPPPRGPGFRGRRGRGEKRKE 1095 + K G G I ++ K FA + E+ + P PG +G +G Sbjct: 936 QGDK---GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL------ 986 Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155 P P PR G G+ NP EP G R PG P + G Sbjct: 987 ------PGPAGPPGPR-------GDLGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 1156 AREGGPKCADRPSVAPKDPLQVPTNTE-TSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214 G P A RP + LQ SE TRP P T + P Sbjct: 1033 ---GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP-------TGDPGLPGD---- 1078 Query: 1215 EALRSPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272 GEMG PG L P P + G+P G PHG G+ Sbjct: 1079 -------MGKKGEMGQPGPPGHLGPAGPEGA---PGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 1273 LLGGPG-----------------GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPS 1315 LLG PG G + + PA + GE A P P Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP--- 1185 Query: 1316 VLSSKISSFGCDPAGFNRDPLGVP--VAKKGPQPYSSPHS----ELFLGPKDLAGCFLEE 1369 G A +R G P +KG + P E F GP L G + Sbjct: 1186 ---------GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236 Query: 1370 L---HPKPSARDAP-------PASSSCLCQDGEDAGSLEPQLPRSPPGTAET--EPGRAA 1417 P +R +P P S + G D GS+ P+ PPGTA PGR Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKG-DKGSMGHPGPKGPPGTAGDMGPPGRLG 1295 Query: 1418 SPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLP--FACADPPQKTVPSDPP 1469 +P T P LP R DP G + G P PP P PP Sbjct: 1296 APGT-------PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Score = 77.8 bits (190), Expect = 2e-13 Identities = 289/1237 (23%), Positives = 378/1237 (30%), Gaps = 221/1237 (17%) Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPIPKGS 262 PGPP + + P + + + D P + PG ++G P Sbjct: 238 PGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297 Query: 263 RPG-----GSP--RGVSFQFPFPALHGAS-TKPFPADVAGHAFTNGPLVFAFHQPQGAWP 314 +PG G P GV FP L G K D+ F + +Q +G Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG--- 354 Query: 315 EEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372 + GP P + PS P G PG + L GA PG S Sbjct: 355 -DEGTPGPPGPRGARGPQGPSGPPGVPGSPG--SSRPGLRGAPGWPGLKGSKG------- 404 Query: 373 HKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP 432 ER +D +G T G P PG PGPP + GP Sbjct: 405 ---------ERGRPGKDAMG-TPGSPGCAGSPGLPGSP-------GPPGPPGDIVFRKGP 447 Query: 433 PPAR-LP-QLWDPTAAPYPTPPGGP-LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489 P LP L P P G P L T+ + G P L +P Q Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL-----PAVRSSQG-- 542 + SP G + LP G P QG G G G+T P ++ P +R G Sbjct: 508 GLKGSP-GSPGNTGLPGFPGFPGAQG-DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565 Query: 543 ---GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH--GTPSLPPPRVVGASPSESPLPSPA 597 G P G+ P + G Q P G+P P P P P P Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625 Query: 598 TN-TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP--------- 647 T G + P + P S + +PGP GP PP HP G P Sbjct: 626 LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG---PPGHPGPQGPPGIPGSLGKC 682 Query: 648 ----FPSPEPPHSLPTHYQPEPA-----KAFPFPADGLGAEG------------------ 680 P P+ +P P P + FP LG G Sbjct: 683 GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742 Query: 681 ----AFQCLEETP-FPHEGPEVGRGGLQGFPRAPP-PYPTHHFSLSSASLD--------Q 726 A TP FP E G G G P P P + L D + Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802 Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL-----PSPPAAPR 781 C + R L + G R K G + PG PGL P +P Sbjct: 803 QGPPGRCIEGPRGAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPG 859 Query: 782 VPA-DAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFP-----LPASDLDME 835 +P G L G G+D + P P P P Sbjct: 860 IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919 Query: 836 DDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT--P 893 T G + NP S V D+ G +G + K GV P Sbjct: 920 IPGVKGQRGTPGAKGEQGDKGNPG-PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978 Query: 894 ESKAPP--PLPAATPDPQ-----TPRPGDRGCPARGRPKTR-SLGLAPTEADAPSQGRQQ 945 K P PA P P+ T PG+ G RG P + ++G+ ++ + G Sbjct: 979 GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Query: 946 RRGKQ----LKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQA 1001 R G+ + + D G +EG+ G G P + GL P ++ Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG------PTGDPGL---PGDMGKKGEMGQ 1087 Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061 PG P P A S LP + P G G + I K L Sbjct: 1088 PGPPGHLGPAGPEGAP-----GSPGSPGLPGKPGPH------GDLGFKGI------KGLL 1130 Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR-------GEKRKE--VELTQGPREDEPQKPR 1111 P GP G RG +GR GEK + + GPR + + Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190 Query: 1112 KAARQEAGGDGAP--------ANPEEPGGSR--PGPGRSPQARGPSRSLETGAAAREGGP 1161 K R G G P A P P G PGP P A P ++ G G P Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS------TEFTE 1215 AP P ++ + + S+ P P TA + P T Sbjct: 1251 G-------APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 1216 ALRSPPA-----ACAGEMG--------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH 1262 R P GE G PG + P+ PP R D GT K + P Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 1263 GSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297 G+ PG+ G GP G P K +PG Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400 Score = 69.7 bits (169), Expect = 5e-11 Identities = 281/1179 (23%), Positives = 364/1179 (30%), Gaps = 217/1179 (18%) Query: 65 PRQAR--DGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122 PR AR G PP + G SS PG RG+P P + R A G+P Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP--- 420 Query: 123 GIASSRTKPTLDETPENP-----------------QLEAAQLPEVDTPQG-PG---TGAP 161 G A S P P P L + +P VD P+G PG T P Sbjct: 421 GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP 480 Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP 221 PG P P G ++ + SP T P PG P ++G L+ Sbjct: 481 YIPGPPGLPGLPGLH--GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538 Query: 222 GSYPEYQASGADSWP--PAAENSFPGANF-----GVPPAEPEPIPKGSRPGGSPRGVSFQ 274 Q G P P PG G P + P PKG +G Q Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKG--DQ 595 Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSP 334 P P G+ P PA AG P G P+ G +P P P Sbjct: 596 GP-PGDPGSPGSPGPAGPAG--------------PPGYGPQGEPGLQGTQGVPGAPGP-- 638 Query: 335 LPCYQGQPGGLNRHSDLSGALSSPG-AAHSAPR---PFSDSLHKSLTKILPERPPSAQDG 390 P G G L+ + + G PG H P+ SL K LP P + G Sbjct: 639 -PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP--GPDGEPG 695 Query: 391 LGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY 448 + GPP + FPG G PG ++ PG P P L P Sbjct: 696 IPGIGFPGPPGPKGDQGFPG----TKGSLGCPG----KMGEPGLPGK--PGLPGAKGEPA 745 Query: 449 PTPPGGPLAATRSMFFNGQPS-PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP 507 PGGP G P PG+R HG L LP Sbjct: 746 VAMPGGP----------GTPGFPGER-----------------GNSGEHGEIGLPGLPGL 778 Query: 508 AGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGV 565 G P G G G G+ P E+ P R +G G+ L NG+ + Sbjct: 779 PGTP-GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR------ 831 Query: 566 AQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPS---- 619 + + P G P +P G S P + + G + P+ P NP Sbjct: 832 -RGKTGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQ-GEMGPLGQRGYPGNPGILGP 884 Query: 620 -SEESQL-----PGPLGPSAFFHPPTHPQETGSP-FPSPEPPHSLPTHYQPEPAKAFPFP 672 E+ + PG +GP P P + GSP P + P + K P P Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944 Query: 673 AD-----GLGAEGAFQCLEETPFPHEGPEV----GRGGLQGFP-RAPPPYPTHHFSLSS- 721 ++ G E + P V G GL+G P A PP P + Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004 Query: 722 ----------ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG-- 769 S+ + + + F GL G + PG Sbjct: 1005 PGEPGLRGIPGSMGNMGM-----PGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059 Query: 770 ---PPGLPSPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPF 825 PG P P P +P D G + G A EG + LP Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----- 1114 Query: 826 PLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPL 885 P P DL + L L + G P P G RG + Sbjct: 1115 PGPHGDLGFKGIKGL--LGPPGIRGPPGLPGFP----------GSPGPMGIRGDQGRDGI 1162 Query: 886 KSKAGVTPES--KAPPPLPAATPDPQTPRPGDRGCPA-RGRP-KTRSLGLAPTEADAPSQ 941 AG E+ PP P P Q + GDRG P G P + ++G A + Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221 Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL----GERPPPRPRRP 997 G G + + G GS G G G+ G P P+ P Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281 Query: 998 -----------RTQAPGSRADPAPR-VPRAAALP----EETRSSRRRRLPPRKDPRKRKA 1041 R APG+ P PR P P E+ + P P K Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGPKG 1340 Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGP-------GFRGRRGRGEKRK 1094 G G LKI+ E +P P GP G RG+ G+ K Sbjct: 1341 PPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400 Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGS 1133 T GP ++ K K AG DG P + G S Sbjct: 1401 ----TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDS 1435 Score = 69.3 bits (168), Expect = 7e-11 Identities = 200/845 (23%), Positives = 263/845 (31%), Gaps = 154/845 (18%) Query: 477 PQSAPLPWPQVLPTARPSPH-GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR---- 531 PQ LP VL A P+ G + G + + G +G G G +PG + Sbjct: 9 PQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPG-SPGQKGFTG 67 Query: 532 -EKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASP 588 E LP + +G G P L G+ P F G +P T V G S Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127 Query: 589 SESP-----LPSPATNTAGSTCSSLSPMSSSPANPSSEESQ------LPGPLGPSAFFHP 637 S+ LP + L +PA E LPG GP P Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187 Query: 638 PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEV 697 P P G P P F FP +G G + E H+G E Sbjct: 188 PGFPGPVG----------------PPGPPGFFGFPG-AMGPRGPKGHMGERVIGHKG-ER 229 Query: 698 GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLL 757 G GL G P PP V++T D N + L Sbjct: 230 GVKGLTG-PPGPPG----------------TVIVTLTGPD-NRTDL-------------- 257 Query: 758 ARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817 + + G + + G PG P P P + G GD +GK Sbjct: 258 -KGEKGDKGAMGEPGPPGPSGLPGESYGSEKG---------APGDPGLQGK--------- 298 Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877 P P P S+ ++ + L+ E +G++ Q D P G R Sbjct: 299 PGKDGVP-GFPGSE-GVKGNRGFPGLMGE--DGIKGQK-------------GDIGPPGFR 341 Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPR--PGDRGCPARGRPKTRSLGLAPTE 935 GP+ + + G E PP P PQ P PG G P RP R G Sbjct: 342 GPTEYYDTYQEKG--DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR--GAPGWP 397 Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP--- 992 S+G + R GK + + G+ +GS G + G D + + PP Sbjct: 398 GLKGSKGERGRPGKDA------MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451 Query: 993 -------RPRRPRTQA----PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKA 1041 P P PG P +P LP + +P R+ K Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511 Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP-----PRGPGFRGRRGRGEKRKEV 1096 G+ G + + E E QP P PG RG+ GR + + Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGR-KGLDGI 570 Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAA 1156 T G + K A E G G P +P PG P P GP E G Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG--EPGLQG 628 Query: 1157 REGGPKCADRPSVA-PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215 +G P P A P+ L V T P P P P + Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVST---------PVPGPPGPPGPPGHPGPQGPPGIPGSL 679 Query: 1216 ALRSPPAACA--GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273 P GE G PG+ P PP + D G P GSL G PG L Sbjct: 680 GKCGDPGLPGPDGEPGI-PGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737 Query: 1274 LGGPG 1278 G G Sbjct: 738 PGAKG 742 Score = 67.4 bits (163), Expect = 3e-10 Identities = 285/1227 (23%), Positives = 374/1227 (30%), Gaps = 204/1227 (16%) Query: 1682 AEGDSRPPQDVCLPEPS--KQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739 A G+ PP LP S + G D G K D FP E R Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP-------GSEGVKGNRG 318 Query: 1740 LPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASP 1799 P G + E G Q +G P F P + +G P P G Sbjct: 319 FP-----GLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-----PPGPRG 366 Query: 1800 SHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVS 1857 + QG S G G P + RPG G P G+ G++A P SP C Sbjct: 367 ARGPQGPS-GPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP-GSPGCAG 424 Query: 1858 NTHPSRRSQDPALSPP------------------IRQLQLPGPGVAKSKDGILGLQELTP 1899 + P PP + +PG K + G+L Q P Sbjct: 425 S--PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ--CP 480 Query: 1900 AAQSPPRV-NPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958 PP + GL G G+ +GSPG T LP G A G GL Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP---GAQGDPGLK 537 Query: 1959 GQAEKTQGQGTANQLQPENGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAA 2017 G+ +T LQPE V PG + G T G L KG A Sbjct: 538 GEKGET--------LQPEGQVGVPGDPGLRGQPGRKGLDGIPG-TPGVKGLPGPKGELAL 588 Query: 2018 MSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077 + + P P SP A +G G P+ PGL G P Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPA-------GPAGPPGYGPQ--GEPGLQGTQGVPGAPGPP 639 Query: 2078 SV----GDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133 G+L+ P P P GP P P G LG P P G Sbjct: 640 GEAGPRGELSVSTPVPGP----PGPPGPPGHPGP-QGPPGIPGSLG--KCGDPGLPGPDG 692 Query: 2134 PQQLLACSPAWAPLEEAD-GVQATTDT----GAEDSPVAP--PSLTTSPCDPKEALAGCL 2186 + P + D G T + G P P P L + +P A+ G Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-- 750 Query: 2187 LQGEGS---PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243 G G+ P E +S G + TP + L P R + P P Sbjct: 751 --GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGP 805 Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302 P P A GL+ G + Q G RG GP +G P DR + S Sbjct: 806 PGRCIEGPRGAQGLPGLN----GLKGQQGRRGKTGP----KGDPGIPGLDRSGFPGETGS 857 Query: 2303 PSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK--EPEDPGTPETGRS 2360 P G P P L G D + G G P +PGTP G+ Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP--GQR 915 Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420 G+ +P V G+ P + +P + +G+P Sbjct: 916 GSPGIPGVK--------GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP--------GL 959 Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480 +G+ P N R PG+ K K P P P P Sbjct: 960 KGFAGNPGEKGN---------------------RGVPGMPGLKGLKGLPGPAGPPGPRGD 998 Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP--PPAQGSKEVLRAPG 2538 P EP + P + + G + + G P +P P G + PG Sbjct: 999 LGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057 Query: 2539 SPHSQQLHPPSPT-----EHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593 + PP PT ++ K +P P L P E G Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP----PGHLGPAGPEGAPGSPGSPGLPG 1113 Query: 2594 DSPSHSEGKSNKKRGKLRGRRLREESILP----------VSADVISDGRGSRPSPA---- 2639 H + +G L +R LP + D GR P PA Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD---QGRDGIPGPAGEKG 1170 Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698 A P G P A G + R A PG + G +A G TG + PG Sbjct: 1171 ETGLLRAPP----GPRGNPGAQGAKGDRGAPGFPG-LPGRKGAMGDAGPRGPTGIEGFPG 1225 Query: 2699 DRMLCPGRMDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757 L + G P G +G+ A G GP + +G+ + GS + Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS-----MGHPGPKG 1280 Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP------DNPDTQGGVQGPEGPTP 2811 G + PP G LG P T P QG P NP G + GP GP Sbjct: 1281 PPGTAGDMGPP-GRLGAPGTPGLPGPRGDPG-FQGFPGVKGEKGNPGFLGSI-GPPGPI- 1336 Query: 2812 DASGSSAKDPPSLFDDEVSFSQLFPPG 2838 K PP + D + + PG Sbjct: 1337 -----GPKGPPGVRGDPGTLKIISLPG 1358 Score = 65.1 bits (157), Expect = 1e-09 Identities = 176/713 (24%), Positives = 227/713 (31%), Gaps = 137/713 (19%) Query: 28 GHPSQP-PLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSST 86 G P QP P + P R +G R A G L Q R+ + G P + G S Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851 Query: 87 PGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQ 146 PG+ GSP P + + + G P ILG P ++ Sbjct: 852 PGETGSPGIPGHQGEMGPLGQ-----RGYPGNPGILG-------PPGEDGVIGMMGFPGA 899 Query: 147 LPEVDTPQGPGT----GAPLRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSA 201 + P PGT G+P PG+ P A+ E G S + P Sbjct: 900 IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL 959 Query: 202 TPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKG 261 PG +RG P PG G P A P + G EP +G Sbjct: 960 KGFAGNPGEKGNRGV-PGMPG------LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012 Query: 262 --------SRPGGSPRGVSFQFP-------FPALHG-----------ASTKPFPADVAGH 295 PG + + FP P +HG T+P P G Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGD 1072 Query: 296 AFTNGPL----VFAFHQPQG----AWPEEAVGTGPAYPLPTQPAPSPLPCYQG-----QP 342 G + P G A PE A G+ + LP +P P ++G P Sbjct: 1073 PGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP 1132 Query: 343 GGLNRHSDLSGALSSPG--------AAHSAPRPFSDSLHKSLTKIL--PERPPSAQDGLG 392 G+ L G SPG P P + L + P P AQ G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 393 STRGPPSSLPQRHFPGQAYRASGV-DTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTP 451 RG P FPG R + D P P PGPP LP P P Sbjct: 1193 D-RGAPG------FPGLPGRKGAMGDAGPRGPTGIEGFPGPP--GLPGAIIPGQTGNRGP 1243 Query: 452 PGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP 511 PG + SPG AP P P P G ++ G Sbjct: 1244 PG------------SRGSPG--------APGP---------PGPPGSHVI--------GI 1266 Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571 + GS G G G + P R G+P L G DPG Q F GV + + Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG--DPGFQG-FPGVKGEKGN 1323 Query: 572 PHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSE-ESQLPGP-- 628 P S+ PP +G P T S S P +P P + E PGP Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP-PGTPGEPGMQGEPGPPGPPG 1382 Query: 629 -LGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEG 680 LGP P + G+P P+ E + + +K P PA G G Sbjct: 1383 NLGPCGPRGKPGKDGKPGTPGPAGEKGN--------KGSKGEPGPAGSDGLPG 1427 Score = 58.9 bits (141), Expect = 9e-08 Identities = 116/476 (24%), Positives = 150/476 (31%), Gaps = 78/476 (16%) Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488 G PG+K +P + +PG A PG PRG P L + + Sbjct: 964 GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG-----PRGDLGSTGNPGEPGLRGIPGSMG 1018 Query: 3489 ----PST-----TKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRG 3539 P + T G+P RP P H ++G + + E P P P G Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPG-PPGPTGDPGLPG 1077 Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG----QDAEGKRAPLVFSG 3594 D G + +P G GP P LP +PG G + +G P G Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137 Query: 3595 KRRAPGARGRCAPDHFQEDHLLQ-----KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649 PG G P + D ++ + + + GPRG G Q Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN---------PGAQ 1188 Query: 3650 SSSKDRSAASTPS----KALKFPVHPRKAVGSLA-------PGELARGTENGMKPATPKA 3698 + DR A P K PR G PG + G P + Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248 Query: 3699 KPG-PSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756 PG P G GS G K GS P P P + P R Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPG--------------PKGPPGTAGDMGPPGRL 1294 Query: 3757 QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP 3816 A P G GP G P +G K +KG PG +GS G P P P Sbjct: 1295 GA------PGTPGLPGPRGD--PGFQGFPGVKGEKGN-PG-----FLGSIG--PPGPIGP 1338 Query: 3817 PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 P + P L P S P P + EPG LG P+G+P Sbjct: 1339 KGPPGVRGDPG-TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Score = 46.2 bits (108), Expect = 6e-04 Identities = 119/452 (26%), Positives = 148/452 (32%), Gaps = 83/452 (18%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG+PGQK LP + PG P GS + LP Sbjct: 57 PGSPGQKGFTGPEGLPGPQGPKGFPG--------LPGLTGSKGVRGISGLPGF------- 101 Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP--PPSLS----PFPAALADGRGDC 3541 S + G P T + GC Q P P +L P A L +G Sbjct: 102 --SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 3542 AL--DGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAP 3599 A D L+ + PG+PGP Q LP P P G P F G P Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGP-------VGPPGPPGFFG---FP 206 Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP---AGCQSSSKDRS 3656 GA G P + ++ + E + GP GT + T P + D+ Sbjct: 207 GAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIV-TLTGPDNRTDLKGEKGDKG 265 Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG-------PSSQGS 3707 A P P P S PGE + G+E G P P + KPG P S+G Sbjct: 266 AMGEPG-----PPGP-----SGLPGE-SYGSEKG-APGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 3708 GSPR--PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765 R PG G + Q G + P + + E P GP Sbjct: 314 KGNRGFPGLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-------PPGP 364 Query: 3766 REA-GEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824 R A G QGP G G SS +G P S G GR P +P Sbjct: 365 RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAG 424 Query: 3825 TPSRVLPTKPKPNSQNKPRPPPS-EQRKAEPG 3855 +P LP P P P PP RK PG Sbjct: 425 SPG--LPGSPGP-----PGPPGDIVFRKGPPG 449 Score = 44.3 bits (103), Expect = 0.002 Identities = 115/447 (25%), Positives = 136/447 (30%), Gaps = 89/447 (19%) Query: 3414 RGGRQPFAFRG-VRRPGAPGQKARALEGTLP--SKRRRVAMPGSAPGPGEDRPPPRGSSP 3470 +G R F G RPG PG + P S+ R PG PG P G Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG--LPGDMGKKG 1083 Query: 3471 ILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP------IRGCELPSNHQECPP 3524 + + P L P G P + P P H I+G P + P Sbjct: 1084 EMGQPGPPGHL---GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--P 1138 Query: 3525 PSLSPFPAALADG--RGDCALDG----ALERPEN---------EASPGSPGPLLQQALPL 3569 P L FP + RGD DG A E+ E +PG+ G + P Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198 Query: 3570 GASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628 LP R GA G G R P G PG G P Sbjct: 1199 FPGLPGRKGAMGD--AGPRGPTGIEGFPGPPGLPGAIIPGQ------------------T 1238 Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGT 3687 GP G+ A P G S S P P G + P G L Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA-- 1296 Query: 3688 ENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR-- 3745 P TP PGP PG K G + P G L S P P P Sbjct: 1297 -----PGTP-GLPGPRGDPGFQGFPGVK---GEKGNP--GFLGSIGPPGPIGPKGPPGVR 1345 Query: 3746 -------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792 SP P P + E G GP G+LGP K K Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQG------EPGPPGPPGNLGPCGPRGKPGKDGKP 1399 Query: 3793 QVPGPARSE-SVGSFGR-APSAPDKPP 3817 PGPA + + GS G P+ D P Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGSDGLP 1426 Score = 40.8 bits (94), Expect = 0.027 Identities = 117/495 (23%), Positives = 146/495 (29%), Gaps = 74/495 (14%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG PG K LP + +A+ G G P SP + + P E Sbjct: 571 PGTPGVKG------LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP 624 Query: 3488 APSTTKGWPETLERPVDP-------VTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG 3539 T+G P P + V+ P+ G P P P P P +L G Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL----G 680 Query: 3540 DCALDGALERPENEAS------PGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF 3592 C D L P+ E PG PGP Q P SL PG G+ Sbjct: 681 KCG-DPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG--------L 731 Query: 3593 SGKRRAPGARGR--CAPDHFQEDHLLQKEKEVSSSH----MVSEGGPRGTFHKGSATKPA 3646 GK PGA+G A E+ S H + G GT P Sbjct: 732 PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791 Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT-PKAKPG---- 3701 G P + ++ PR A G PG + G + T PK PG Sbjct: 792 GDPGQPGPPGEQGPPGRCIE---GPRGAQG--LPGLNGLKGQQGRRGKTGPKGDPGIPGL 846 Query: 3702 --------------PSSQGSGSP--RPGTKTGGGSQPQPAS----GQLQSETATTPAKPS 3741 P QG P + G G P G + A P P Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906 Query: 3742 FPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPGP 3797 +P P K P GEQG G+ GP E G+ KG P Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966 Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHT 3857 + G G K P P L + P P S PG Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Query: 3858 QRKDRLGKAFPQGRP 3872 ++ LG GRP Sbjct: 1027 GKRGTLGFPGRAGRP 1041 Score = 37.7 bits (86), Expect = 0.23 Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 9/115 (7%) Query: 3176 RGQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAK 3235 RGQ R D G+ G+ V L E A +G + GSPG P G G A Sbjct: 559 RGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAG 614 Query: 3236 KDSPGERAKPRARSTPS-----NPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285 G + +P + T P G A P + + G PGPP P P Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669 Score = 35.0 bits (79), Expect = 1.5 Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%) Query: 3183 LGDLPG-----GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKD 3237 L LPG G+ G A L S P G A G PG G++GE + Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK-GEKGETLQP 546 Query: 3238 S--------PGERAKPRARST---PSNPDGAATPDSASATALA----DAGSPGPPRTTPS 3282 PG R +P + P P P AL+ D G PG P + S Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 3283 PSPDPWAG-------GEPLLQAT 3298 P P AG GEP LQ T Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGT 629 Score = 32.3 bits (72), Expect = 9.5 Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 28/116 (24%) Query: 3205 EPAPKHHRGK--RSAGKAAGSPGDPWGQEGEAKKDS----PGERAKPRARSTPS------ 3252 EP P G S G G+PGDP G +G+ KD PG R P Sbjct: 269 EPGPPGPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327 Query: 3253 --------NPDGAATPDSASAT--ALADAGSPGPP-----RTTPSPSPDPWAGGEP 3293 P G P T D G+PGPP R PS P G P Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 90.9 bits (224), Expect = 2e-17 Identities = 255/1046 (24%), Positives = 328/1046 (31%), Gaps = 188/1046 (17%) Query: 1 MPG-ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED--NTPATRTTKGAREAGGQAQA 57 +PG + P+G P T Q + PG P P L P + G + + G Sbjct: 462 IPGVDGPKGEPGLLCT---QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518 Query: 58 MELPEAQPRQARDGELKPPSLRGQA-----PSSTPGKRGSP--QTPPGRSPLQAPSRLAG 110 LP G+ P L+G+ P G G P + PGR L G Sbjct: 519 TGLPGFPGFPGAQGD---PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575 Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGP-GTGAPLRPGLPRT 169 +G P + L ++ + P +P P P GP G G PGL T Sbjct: 576 -VKGLPGPKGELALSGEKGDQGPPGDPGSPGS-----PGPAGPAGPPGYGPQGEPGLQGT 629 Query: 170 EAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQ--PGSYPEY 227 + P A PP S S TP P PGPP G Q PG Sbjct: 630 QGVPGAPG---------PPGEAGPRGELSVS-TPVPGPPGPPGPPGHPGPQGPPGIPGSL 679 Query: 228 QASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSR--PGGSPR-GVSFQFPFPALHGA 283 G P P E PG F PP PKG + PG G + P L G Sbjct: 680 GKCGDPGLPGPDGEPGIPGIGFPGPPG-----PKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQP 342 P A GP F +G E P P LP P L +G P Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 343 GGLNRHSDLSGALSSPGAAHSAPR-----PFSDSLH-------KSLTKILPERPPSAQDG 390 G G PG PR P + L K+ K P P + G Sbjct: 795 G----QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850 Query: 391 LGSTRGPPS---------SLPQRHFPGQA--------------YRASGVDTSPGPPDT-- 425 G P L QR +PG G PGPP Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910 Query: 426 ---ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPL 482 + +PG P + Q P A G P + S + PG L A Sbjct: 911 TPGQRGSPGIPGVK-GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG----LKGFAGN 965 Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK--------- 533 P + P G++ L LP PAG P G +G LG+ G P + Sbjct: 966 PGEKG-NRGVPGMPGLKGLKGLPGPAGPP----GPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 534 -LPAVRSSQG--------GSPALFTYNGMTDPGAQPLFFGVAQP-QVSPHGTPSLPPPRV 583 +P + +G G P L +G+ +P + +P P G P LP Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSS-PANPSSEESQ----LPGPLGPSAFFHPP 638 + P P AG + SP S P P + G LGP PP Sbjct: 1081 KKGEMGQ-PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 639 THPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVG 698 P GSP P + P PA G +G L P P P G Sbjct: 1140 GLPGFPGSPGPMGIRGD--------QGRDGIPGPA---GEKGETGLLRAPPGPRGNP--G 1186 Query: 699 RGGLQGFPRAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLL 756 G +G AP P P ++ A R + + F G + Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAG-------------PRGPTGIEGFPGPPGLPGAI 1233 Query: 757 LA-----RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811 + R G + SPG PG P PP + + G + H G A G Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871 L P L P P D + G++ + NP F+ Sbjct: 1294 LGAPGTPGL-----PGPRGDPGF-----------QGFPGVKGEKGNP----GFLGSIGPP 1333 Query: 872 EPSGPRGPSS--GHPLKSKAGVTPESKAPPPLPA-----ATPDPQTPRPGDRG-CPARGR 923 P GP+GP G P K P S PP P P P P PG+ G C RG+ Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP-PGNLGPCGPRGK 1392 Query: 924 PKTRSLGLAPTEADAPSQGRQQRRGK 949 P G T A +G + +G+ Sbjct: 1393 PGKD--GKPGTPGPAGEKGNKGSKGE 1416 Score = 86.7 bits (213), Expect = 4e-16 Identities = 353/1494 (23%), Positives = 441/1494 (29%), Gaps = 412/1494 (27%) Query: 184 FQEPPSSFTSTNYTSPSATPRPPAP----------GPPQSRGTS-----------PLQPG 222 F PP S +T P P P P G RG S P PG Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPG 112 Query: 223 SYPEYQASGADSWPPA-AENSFPG--ANFGVP--------------PAEPEPIPKGSR-- 263 + Y G + E FPG G P PA+ E I ++ Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172 Query: 264 PG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG-- 319 PG G+P P P G P P G GP P+G E +G Sbjct: 173 PGLPGAPGPQGLPGP-PGFPGPVGPPGPPGFFGFPGAMGP-----RGPKGHMGERVIGHK 226 Query: 320 --------TGPAYP----LPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAP 365 TGP P + T P +G+ G G G PG ++ + Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286 Query: 366 R--PFSDSLHKSLTKI-LPERPPSAQDGLGSTRGPPSSLPQRHFPGQ------------- 409 + P L K +P P S +G+ RG P + + GQ Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGS--EGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344 Query: 410 ----AYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP-YPTPPGGPLAATR---- 460 Y+ G + +PGP PGP AR PQ P+ P P PG R Sbjct: 345 EYYDTYQEKGDEGTPGP-------PGPRGARGPQ--GPSGPPGVPGSPGSSRPGLRGAPG 395 Query: 461 ------SMFFNGQP------SPGQRLC-----LPQSAPLPWPQ---VLPTARPSPHGME- 499 S G+P +PG C LP S P P V P HG+ Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455 Query: 500 -------------------MLSRLPFPAGGPEWQG-----------GSQGALGTAGKTPG 529 + ++ P+ G P G G QGA G G Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515 Query: 530 P-REKLPAVRSSQG--GSPALFTYNGMT-----------DPG--AQPLFFGVAQPQVSPH 573 P LP G G P L G T DPG QP G+ +P Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP- 574 Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPS 632 G LP P+ A E P G S SP + PA P Q PG G Sbjct: 575 GVKGLPGPKGELALSGEKGDQGP----PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630 Query: 633 AFFHPPTHPQETG--------SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQC 684 P P E G +P P P P P H P+ P G G Sbjct: 631 GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---- 686 Query: 685 LEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLA 744 P E G G+ GFP P P F + SL Sbjct: 687 -----LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG------------------- 721 Query: 745 AFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQ 804 K G PG PGLP P V G T G+ Sbjct: 722 -------------CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG------TPGFPGERG 762 Query: 805 AEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSF 864 G+ + LP L TP E L+G P Sbjct: 763 NSGEHGEIGLPGLPGLPGTPG-------------------NEGLDGPRGDPGQP------ 797 Query: 865 IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924 P G +GP G ++ G ++ P L Q R G G +G P Sbjct: 798 -------GPPGEQGP-PGRCIEGPRG----AQGLPGLNGL--KGQQGRRGKTG--PKGDP 841 Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984 L + + S G +G+ L ++ G G L P D Sbjct: 842 GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR-------------GYPGNPGILGPPGED 888 Query: 985 GL--------GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDP 1036 G+ PP P P T PG R P +P +R P K Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGT--PGQRGSPG--IPGVKG---------QRGTPGAKGE 935 Query: 1037 RKRKARGGAWGKELILKIVQQKNRLREYDFA-SESEEDEQPPPRGPGFRGRRGRGEKRKE 1095 + K G G I ++ K FA + E+ + P PG +G +G Sbjct: 936 QGDK---GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL------ 986 Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155 P P PR G G+ NP EP G R PG P + G Sbjct: 987 ------PGPAGPPGPR-------GDLGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 1156 AREGGPKCADRPSVAPKDPLQVPTNTE-TSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214 G P A RP + LQ SE TRP P T + P Sbjct: 1033 ---GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP-------TGDPGLPGD---- 1078 Query: 1215 EALRSPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272 GEMG PG L P P + G+P G PHG G+ Sbjct: 1079 -------MGKKGEMGQPGPPGHLGPAGPEGA---PGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 1273 LLGGPG-----------------GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPS 1315 LLG PG G + + PA + GE A P P Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP--- 1185 Query: 1316 VLSSKISSFGCDPAGFNRDPLGVP--VAKKGPQPYSSPHS----ELFLGPKDLAGCFLEE 1369 G A +R G P +KG + P E F GP L G + Sbjct: 1186 ---------GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236 Query: 1370 L---HPKPSARDAP-------PASSSCLCQDGEDAGSLEPQLPRSPPGTAET--EPGRAA 1417 P +R +P P S + G D GS+ P+ PPGTA PGR Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKG-DKGSMGHPGPKGPPGTAGDMGPPGRLG 1295 Query: 1418 SPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLP--FACADPPQKTVPSDPP 1469 +P T P LP R DP G + G P PP P PP Sbjct: 1296 APGT-------PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Score = 77.8 bits (190), Expect = 2e-13 Identities = 289/1237 (23%), Positives = 378/1237 (30%), Gaps = 221/1237 (17%) Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPIPKGS 262 PGPP + + P + + + D P + PG ++G P Sbjct: 238 PGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297 Query: 263 RPG-----GSP--RGVSFQFPFPALHGAS-TKPFPADVAGHAFTNGPLVFAFHQPQGAWP 314 +PG G P GV FP L G K D+ F + +Q +G Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG--- 354 Query: 315 EEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372 + GP P + PS P G PG + L GA PG S Sbjct: 355 -DEGTPGPPGPRGARGPQGPSGPPGVPGSPG--SSRPGLRGAPGWPGLKGSKG------- 404 Query: 373 HKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP 432 ER +D +G T G P PG PGPP + GP Sbjct: 405 ---------ERGRPGKDAMG-TPGSPGCAGSPGLPGSP-------GPPGPPGDIVFRKGP 447 Query: 433 PPAR-LP-QLWDPTAAPYPTPPGGP-LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489 P LP L P P G P L T+ + G P L +P Q Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL-----PAVRSSQG-- 542 + SP G + LP G P QG G G G+T P ++ P +R G Sbjct: 508 GLKGSP-GSPGNTGLPGFPGFPGAQG-DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565 Query: 543 ---GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH--GTPSLPPPRVVGASPSESPLPSPA 597 G P G+ P + G Q P G+P P P P P P Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625 Query: 598 TN-TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP--------- 647 T G + P + P S + +PGP GP PP HP G P Sbjct: 626 LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG---PPGHPGPQGPPGIPGSLGKC 682 Query: 648 ----FPSPEPPHSLPTHYQPEPA-----KAFPFPADGLGAEG------------------ 680 P P+ +P P P + FP LG G Sbjct: 683 GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742 Query: 681 ----AFQCLEETP-FPHEGPEVGRGGLQGFPRAPP-PYPTHHFSLSSASLD--------Q 726 A TP FP E G G G P P P + L D + Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802 Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL-----PSPPAAPR 781 C + R L + G R K G + PG PGL P +P Sbjct: 803 QGPPGRCIEGPRGAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPG 859 Query: 782 VPA-DAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFP-----LPASDLDME 835 +P G L G G+D + P P P P Sbjct: 860 IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919 Query: 836 DDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT--P 893 T G + NP S V D+ G +G + K GV P Sbjct: 920 IPGVKGQRGTPGAKGEQGDKGNPG-PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978 Query: 894 ESKAPP--PLPAATPDPQ-----TPRPGDRGCPARGRPKTR-SLGLAPTEADAPSQGRQQ 945 K P PA P P+ T PG+ G RG P + ++G+ ++ + G Sbjct: 979 GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Query: 946 RRGKQ----LKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQA 1001 R G+ + + D G +EG+ G G P + GL P ++ Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG------PTGDPGL---PGDMGKKGEMGQ 1087 Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061 PG P P A S LP + P G G + I K L Sbjct: 1088 PGPPGHLGPAGPEGAP-----GSPGSPGLPGKPGPH------GDLGFKGI------KGLL 1130 Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR-------GEKRKE--VELTQGPREDEPQKPR 1111 P GP G RG +GR GEK + + GPR + + Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190 Query: 1112 KAARQEAGGDGAP--------ANPEEPGGSR--PGPGRSPQARGPSRSLETGAAAREGGP 1161 K R G G P A P P G PGP P A P ++ G G P Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS------TEFTE 1215 AP P ++ + + S+ P P TA + P T Sbjct: 1251 G-------APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP 1303 Query: 1216 ALRSPPA-----ACAGEMG--------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH 1262 R P GE G PG + P+ PP R D GT K + P Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363 Query: 1263 GSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297 G+ PG+ G GP G P K +PG Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400 Score = 69.7 bits (169), Expect = 5e-11 Identities = 281/1179 (23%), Positives = 364/1179 (30%), Gaps = 217/1179 (18%) Query: 65 PRQAR--DGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122 PR AR G PP + G SS PG RG+P P + R A G+P Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP--- 420 Query: 123 GIASSRTKPTLDETPENP-----------------QLEAAQLPEVDTPQG-PG---TGAP 161 G A S P P P L + +P VD P+G PG T P Sbjct: 421 GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP 480 Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP 221 PG P P G ++ + SP T P PG P ++G L+ Sbjct: 481 YIPGPPGLPGLPGLH--GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538 Query: 222 GSYPEYQASGADSWP--PAAENSFPGANF-----GVPPAEPEPIPKGSRPGGSPRGVSFQ 274 Q G P P PG G P + P PKG +G Q Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKG--DQ 595 Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSP 334 P P G+ P PA AG P G P+ G +P P P Sbjct: 596 GP-PGDPGSPGSPGPAGPAG--------------PPGYGPQGEPGLQGTQGVPGAPGP-- 638 Query: 335 LPCYQGQPGGLNRHSDLSGALSSPG-AAHSAPR---PFSDSLHKSLTKILPERPPSAQDG 390 P G G L+ + + G PG H P+ SL K LP P + G Sbjct: 639 -PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP--GPDGEPG 695 Query: 391 LGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY 448 + GPP + FPG G PG ++ PG P P L P Sbjct: 696 IPGIGFPGPPGPKGDQGFPG----TKGSLGCPG----KMGEPGLPGK--PGLPGAKGEPA 745 Query: 449 PTPPGGPLAATRSMFFNGQPS-PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP 507 PGGP G P PG+R HG L LP Sbjct: 746 VAMPGGP----------GTPGFPGER-----------------GNSGEHGEIGLPGLPGL 778 Query: 508 AGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGV 565 G P G G G G+ P E+ P R +G G+ L NG+ + Sbjct: 779 PGTP-GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR------ 831 Query: 566 AQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPS---- 619 + + P G P +P G S P + + G + P+ P NP Sbjct: 832 -RGKTGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQ-GEMGPLGQRGYPGNPGILGP 884 Query: 620 -SEESQL-----PGPLGPSAFFHPPTHPQETGSP-FPSPEPPHSLPTHYQPEPAKAFPFP 672 E+ + PG +GP P P + GSP P + P + K P P Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944 Query: 673 AD-----GLGAEGAFQCLEETPFPHEGPEV----GRGGLQGFP-RAPPPYPTHHFSLSS- 721 ++ G E + P V G GL+G P A PP P + Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004 Query: 722 ----------ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG-- 769 S+ + + + F GL G + PG Sbjct: 1005 PGEPGLRGIPGSMGNMGM-----PGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059 Query: 770 ---PPGLPSPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPF 825 PG P P P +P D G + G A EG + LP Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----- 1114 Query: 826 PLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPL 885 P P DL + L L + G P P G RG + Sbjct: 1115 PGPHGDLGFKGIKGL--LGPPGIRGPPGLPGFP----------GSPGPMGIRGDQGRDGI 1162 Query: 886 KSKAGVTPES--KAPPPLPAATPDPQTPRPGDRGCPA-RGRP-KTRSLGLAPTEADAPSQ 941 AG E+ PP P P Q + GDRG P G P + ++G A + Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221 Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL----GERPPPRPRRP 997 G G + + G GS G G G+ G P P+ P Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281 Query: 998 -----------RTQAPGSRADPAPR-VPRAAALP----EETRSSRRRRLPPRKDPRKRKA 1041 R APG+ P PR P P E+ + P P K Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGPKG 1340 Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGP-------GFRGRRGRGEKRK 1094 G G LKI+ E +P P GP G RG+ G+ K Sbjct: 1341 PPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400 Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGS 1133 T GP ++ K K AG DG P + G S Sbjct: 1401 ----TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDS 1435 Score = 69.3 bits (168), Expect = 7e-11 Identities = 200/845 (23%), Positives = 263/845 (31%), Gaps = 154/845 (18%) Query: 477 PQSAPLPWPQVLPTARPSPH-GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR---- 531 PQ LP VL A P+ G + G + + G +G G G +PG + Sbjct: 9 PQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPG-SPGQKGFTG 67 Query: 532 -EKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASP 588 E LP + +G G P L G+ P F G +P T V G S Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127 Query: 589 SESP-----LPSPATNTAGSTCSSLSPMSSSPANPSSEESQ------LPGPLGPSAFFHP 637 S+ LP + L +PA E LPG GP P Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187 Query: 638 PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEV 697 P P G P P F FP +G G + E H+G E Sbjct: 188 PGFPGPVG----------------PPGPPGFFGFPG-AMGPRGPKGHMGERVIGHKG-ER 229 Query: 698 GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLL 757 G GL G P PP V++T D N + L Sbjct: 230 GVKGLTG-PPGPPG----------------TVIVTLTGPD-NRTDL-------------- 257 Query: 758 ARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817 + + G + + G PG P P P + G GD +GK Sbjct: 258 -KGEKGDKGAMGEPGPPGPSGLPGESYGSEKG---------APGDPGLQGK--------- 298 Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877 P P P S+ ++ + L+ E +G++ Q D P G R Sbjct: 299 PGKDGVP-GFPGSE-GVKGNRGFPGLMGE--DGIKGQK-------------GDIGPPGFR 341 Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPR--PGDRGCPARGRPKTRSLGLAPTE 935 GP+ + + G E PP P PQ P PG G P RP R G Sbjct: 342 GPTEYYDTYQEKG--DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR--GAPGWP 397 Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP--- 992 S+G + R GK + + G+ +GS G + G D + + PP Sbjct: 398 GLKGSKGERGRPGKDA------MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451 Query: 993 -------RPRRPRTQA----PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKA 1041 P P PG P +P LP + +P R+ K Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511 Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP-----PRGPGFRGRRGRGEKRKEV 1096 G+ G + + E E QP P PG RG+ GR + + Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGR-KGLDGI 570 Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAA 1156 T G + K A E G G P +P PG P P GP E G Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG--EPGLQG 628 Query: 1157 REGGPKCADRPSVA-PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215 +G P P A P+ L V T P P P P + Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVST---------PVPGPPGPPGPPGHPGPQGPPGIPGSL 679 Query: 1216 ALRSPPAACA--GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273 P GE G PG+ P PP + D G P GSL G PG L Sbjct: 680 GKCGDPGLPGPDGEPGI-PGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737 Query: 1274 LGGPG 1278 G G Sbjct: 738 PGAKG 742 Score = 67.4 bits (163), Expect = 3e-10 Identities = 285/1227 (23%), Positives = 374/1227 (30%), Gaps = 204/1227 (16%) Query: 1682 AEGDSRPPQDVCLPEPS--KQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739 A G+ PP LP S + G D G K D FP E R Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP-------GSEGVKGNRG 318 Query: 1740 LPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASP 1799 P G + E G Q +G P F P + +G P P G Sbjct: 319 FP-----GLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-----PPGPRG 366 Query: 1800 SHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVS 1857 + QG S G G P + RPG G P G+ G++A P SP C Sbjct: 367 ARGPQGPS-GPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP-GSPGCAG 424 Query: 1858 NTHPSRRSQDPALSPP------------------IRQLQLPGPGVAKSKDGILGLQELTP 1899 + P PP + +PG K + G+L Q P Sbjct: 425 S--PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ--CP 480 Query: 1900 AAQSPPRV-NPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958 PP + GL G G+ +GSPG T LP G A G GL Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP---GAQGDPGLK 537 Query: 1959 GQAEKTQGQGTANQLQPENGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAA 2017 G+ +T LQPE V PG + G T G L KG A Sbjct: 538 GEKGET--------LQPEGQVGVPGDPGLRGQPGRKGLDGIPG-TPGVKGLPGPKGELAL 588 Query: 2018 MSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077 + + P P SP A +G G P+ PGL G P Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPA-------GPAGPPGYGPQ--GEPGLQGTQGVPGAPGPP 639 Query: 2078 SV----GDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133 G+L+ P P P GP P P G LG P P G Sbjct: 640 GEAGPRGELSVSTPVPGP----PGPPGPPGHPGP-QGPPGIPGSLG--KCGDPGLPGPDG 692 Query: 2134 PQQLLACSPAWAPLEEAD-GVQATTDT----GAEDSPVAP--PSLTTSPCDPKEALAGCL 2186 + P + D G T + G P P P L + +P A+ G Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-- 750 Query: 2187 LQGEGS---PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243 G G+ P E +S G + TP + L P R + P P Sbjct: 751 --GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGP 805 Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302 P P A GL+ G + Q G RG GP +G P DR + S Sbjct: 806 PGRCIEGPRGAQGLPGLN----GLKGQQGRRGKTGP----KGDPGIPGLDRSGFPGETGS 857 Query: 2303 PSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK--EPEDPGTPETGRS 2360 P G P P L G D + G G P +PGTP G+ Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP--GQR 915 Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420 G+ +P V G+ P + +P + +G+P Sbjct: 916 GSPGIPGVK--------GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP--------GL 959 Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480 +G+ P N R PG+ K K P P P P Sbjct: 960 KGFAGNPGEKGN---------------------RGVPGMPGLKGLKGLPGPAGPPGPRGD 998 Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP--PPAQGSKEVLRAPG 2538 P EP + P + + G + + G P +P P G + PG Sbjct: 999 LGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057 Query: 2539 SPHSQQLHPPSPT-----EHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593 + PP PT ++ K +P P L P E G Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP----PGHLGPAGPEGAPGSPGSPGLPG 1113 Query: 2594 DSPSHSEGKSNKKRGKLRGRRLREESILP----------VSADVISDGRGSRPSPA---- 2639 H + +G L +R LP + D GR P PA Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD---QGRDGIPGPAGEKG 1170 Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698 A P G P A G + R A PG + G +A G TG + PG Sbjct: 1171 ETGLLRAPP----GPRGNPGAQGAKGDRGAPGFPG-LPGRKGAMGDAGPRGPTGIEGFPG 1225 Query: 2699 DRMLCPGRMDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757 L + G P G +G+ A G GP + +G+ + GS + Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS-----MGHPGPKG 1280 Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP------DNPDTQGGVQGPEGPTP 2811 G + PP G LG P T P QG P NP G + GP GP Sbjct: 1281 PPGTAGDMGPP-GRLGAPGTPGLPGPRGDPG-FQGFPGVKGEKGNPGFLGSI-GPPGPI- 1336 Query: 2812 DASGSSAKDPPSLFDDEVSFSQLFPPG 2838 K PP + D + + PG Sbjct: 1337 -----GPKGPPGVRGDPGTLKIISLPG 1358 Score = 65.1 bits (157), Expect = 1e-09 Identities = 176/713 (24%), Positives = 227/713 (31%), Gaps = 137/713 (19%) Query: 28 GHPSQP-PLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSST 86 G P QP P + P R +G R A G L Q R+ + G P + G S Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851 Query: 87 PGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQ 146 PG+ GSP P + + + G P ILG P ++ Sbjct: 852 PGETGSPGIPGHQGEMGPLGQ-----RGYPGNPGILG-------PPGEDGVIGMMGFPGA 899 Query: 147 LPEVDTPQGPGT----GAPLRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSA 201 + P PGT G+P PG+ P A+ E G S + P Sbjct: 900 IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL 959 Query: 202 TPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKG 261 PG +RG P PG G P A P + G EP +G Sbjct: 960 KGFAGNPGEKGNRGV-PGMPG------LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012 Query: 262 --------SRPGGSPRGVSFQFP-------FPALHG-----------ASTKPFPADVAGH 295 PG + + FP P +HG T+P P G Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGD 1072 Query: 296 AFTNGPL----VFAFHQPQG----AWPEEAVGTGPAYPLPTQPAPSPLPCYQG-----QP 342 G + P G A PE A G+ + LP +P P ++G P Sbjct: 1073 PGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP 1132 Query: 343 GGLNRHSDLSGALSSPG--------AAHSAPRPFSDSLHKSLTKIL--PERPPSAQDGLG 392 G+ L G SPG P P + L + P P AQ G Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 393 STRGPPSSLPQRHFPGQAYRASGV-DTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTP 451 RG P FPG R + D P P PGPP LP P P Sbjct: 1193 D-RGAPG------FPGLPGRKGAMGDAGPRGPTGIEGFPGPP--GLPGAIIPGQTGNRGP 1243 Query: 452 PGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP 511 PG + SPG AP P P P G ++ G Sbjct: 1244 PG------------SRGSPG--------APGP---------PGPPGSHVI--------GI 1266 Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571 + GS G G G + P R G+P L G DPG Q F GV + + Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG--DPGFQG-FPGVKGEKGN 1323 Query: 572 PHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSE-ESQLPGP-- 628 P S+ PP +G P T S S P +P P + E PGP Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP-PGTPGEPGMQGEPGPPGPPG 1382 Query: 629 -LGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEG 680 LGP P + G+P P+ E + + +K P PA G G Sbjct: 1383 NLGPCGPRGKPGKDGKPGTPGPAGEKGN--------KGSKGEPGPAGSDGLPG 1427 Score = 58.9 bits (141), Expect = 9e-08 Identities = 116/476 (24%), Positives = 150/476 (31%), Gaps = 78/476 (16%) Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488 G PG+K +P + +PG A PG PRG P L + + Sbjct: 964 GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG-----PRGDLGSTGNPGEPGLRGIPGSMG 1018 Query: 3489 ----PST-----TKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRG 3539 P + T G+P RP P H ++G + + E P P P G Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPG-PPGPTGDPGLPG 1077 Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG----QDAEGKRAPLVFSG 3594 D G + +P G GP P LP +PG G + +G P G Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137 Query: 3595 KRRAPGARGRCAPDHFQEDHLLQ-----KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649 PG G P + D ++ + + + GPRG G Q Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN---------PGAQ 1188 Query: 3650 SSSKDRSAASTPS----KALKFPVHPRKAVGSLA-------PGELARGTENGMKPATPKA 3698 + DR A P K PR G PG + G P + Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248 Query: 3699 KPG-PSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756 PG P G GS G K GS P P P + P R Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPG--------------PKGPPGTAGDMGPPGRL 1294 Query: 3757 QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP 3816 A P G GP G P +G K +KG PG +GS G P P P Sbjct: 1295 GA------PGTPGLPGPRGD--PGFQGFPGVKGEKGN-PG-----FLGSIG--PPGPIGP 1338 Query: 3817 PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 P + P L P S P P + EPG LG P+G+P Sbjct: 1339 KGPPGVRGDPG-TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Score = 46.2 bits (108), Expect = 6e-04 Identities = 119/452 (26%), Positives = 148/452 (32%), Gaps = 83/452 (18%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG+PGQK LP + PG P GS + LP Sbjct: 57 PGSPGQKGFTGPEGLPGPQGPKGFPG--------LPGLTGSKGVRGISGLPGF------- 101 Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP--PPSLS----PFPAALADGRGDC 3541 S + G P T + GC Q P P +L P A L +G Sbjct: 102 --SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 3542 AL--DGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAP 3599 A D L+ + PG+PGP Q LP P P G P F G P Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGP-------VGPPGPPGFFG---FP 206 Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP---AGCQSSSKDRS 3656 GA G P + ++ + E + GP GT + T P + D+ Sbjct: 207 GAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIV-TLTGPDNRTDLKGEKGDKG 265 Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG-------PSSQGS 3707 A P P P S PGE + G+E G P P + KPG P S+G Sbjct: 266 AMGEPG-----PPGP-----SGLPGE-SYGSEKG-APGDPGLQGKPGKDGVPGFPGSEGV 313 Query: 3708 GSPR--PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765 R PG G + Q G + P + + E P GP Sbjct: 314 KGNRGFPGLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-------PPGP 364 Query: 3766 REA-GEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824 R A G QGP G G SS +G P S G GR P +P Sbjct: 365 RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAG 424 Query: 3825 TPSRVLPTKPKPNSQNKPRPPPS-EQRKAEPG 3855 +P LP P P P PP RK PG Sbjct: 425 SPG--LPGSPGP-----PGPPGDIVFRKGPPG 449 Score = 44.3 bits (103), Expect = 0.002 Identities = 115/447 (25%), Positives = 136/447 (30%), Gaps = 89/447 (19%) Query: 3414 RGGRQPFAFRG-VRRPGAPGQKARALEGTLP--SKRRRVAMPGSAPGPGEDRPPPRGSSP 3470 +G R F G RPG PG + P S+ R PG PG P G Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG--LPGDMGKKG 1083 Query: 3471 ILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP------IRGCELPSNHQECPP 3524 + + P L P G P + P P H I+G P + P Sbjct: 1084 EMGQPGPPGHL---GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--P 1138 Query: 3525 PSLSPFPAALADG--RGDCALDG----ALERPEN---------EASPGSPGPLLQQALPL 3569 P L FP + RGD DG A E+ E +PG+ G + P Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198 Query: 3570 GASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628 LP R GA G G R P G PG G P Sbjct: 1199 FPGLPGRKGAMGD--AGPRGPTGIEGFPGPPGLPGAIIPGQ------------------T 1238 Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGT 3687 GP G+ A P G S S P P G + P G L Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA-- 1296 Query: 3688 ENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR-- 3745 P TP PGP PG K G + P G L S P P P Sbjct: 1297 -----PGTP-GLPGPRGDPGFQGFPGVK---GEKGNP--GFLGSIGPPGPIGPKGPPGVR 1345 Query: 3746 -------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792 SP P P + E G GP G+LGP K K Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQG------EPGPPGPPGNLGPCGPRGKPGKDGKP 1399 Query: 3793 QVPGPARSE-SVGSFGR-APSAPDKPP 3817 PGPA + + GS G P+ D P Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGSDGLP 1426 Score = 40.8 bits (94), Expect = 0.027 Identities = 117/495 (23%), Positives = 146/495 (29%), Gaps = 74/495 (14%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487 PG PG K LP + +A+ G G P SP + + P E Sbjct: 571 PGTPGVKG------LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP 624 Query: 3488 APSTTKGWPETLERPVDP-------VTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG 3539 T+G P P + V+ P+ G P P P P P +L G Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL----G 680 Query: 3540 DCALDGALERPENEAS------PGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF 3592 C D L P+ E PG PGP Q P SL PG G+ Sbjct: 681 KCG-DPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG--------L 731 Query: 3593 SGKRRAPGARGR--CAPDHFQEDHLLQKEKEVSSSH----MVSEGGPRGTFHKGSATKPA 3646 GK PGA+G A E+ S H + G GT P Sbjct: 732 PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791 Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT-PKAKPG---- 3701 G P + ++ PR A G PG + G + T PK PG Sbjct: 792 GDPGQPGPPGEQGPPGRCIE---GPRGAQG--LPGLNGLKGQQGRRGKTGPKGDPGIPGL 846 Query: 3702 --------------PSSQGSGSP--RPGTKTGGGSQPQPAS----GQLQSETATTPAKPS 3741 P QG P + G G P G + A P P Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906 Query: 3742 FPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPGP 3797 +P P K P GEQG G+ GP E G+ KG P Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966 Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHT 3857 + G G K P P L + P P S PG Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026 Query: 3858 QRKDRLGKAFPQGRP 3872 ++ LG GRP Sbjct: 1027 GKRGTLGFPGRAGRP 1041 Score = 37.7 bits (86), Expect = 0.23 Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 9/115 (7%) Query: 3176 RGQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAK 3235 RGQ R D G+ G+ V L E A +G + GSPG P G G A Sbjct: 559 RGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAG 614 Query: 3236 KDSPGERAKPRARSTPS-----NPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285 G + +P + T P G A P + + G PGPP P P Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669 Score = 35.0 bits (79), Expect = 1.5 Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%) Query: 3183 LGDLPG-----GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKD 3237 L LPG G+ G A L S P G A G PG G++GE + Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK-GEKGETLQP 546 Query: 3238 S--------PGERAKPRARST---PSNPDGAATPDSASATALA----DAGSPGPPRTTPS 3282 PG R +P + P P P AL+ D G PG P + S Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 3283 PSPDPWAG-------GEPLLQAT 3298 P P AG GEP LQ T Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGT 629 Score = 32.3 bits (72), Expect = 9.5 Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 28/116 (24%) Query: 3205 EPAPKHHRGK--RSAGKAAGSPGDPWGQEGEAKKDS----PGERAKPRARSTPS------ 3252 EP P G S G G+PGDP G +G+ KD PG R P Sbjct: 269 EPGPPGPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327 Query: 3253 --------NPDGAATPDSASAT--ALADAGSPGPP-----RTTPSPSPDPWAGGEP 3293 P G P T D G+PGPP R PS P G P Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 90.5 bits (223), Expect = 3e-17 Identities = 262/1076 (24%), Positives = 321/1076 (29%), Gaps = 213/1076 (19%) Query: 6 PRGAP-PPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQ 64 PRG P P G L P+ PG P + D P + G + G P AQ Sbjct: 671 PRGLPGEPGPRGLLGPKGPPGPPGPPGVTGM-DGQPGPKGNVGPQGEPGPPGQQGNPGAQ 729 Query: 65 PRQARDGELKPPSLRGQAPSSTPGKRGSP-----------QTPPGRSPLQAPSRLAGRAE 113 G + PP +G P PG G P + PPG Q P G Sbjct: 730 GLPGPQGAIGPPGEKG--PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPI- 786 Query: 114 GSPPQRYILGIASSR-TKPTLDETPENPQLEAAQLPEVDTPQG-PGTGAPLRPGLPRTEA 171 G P R + G R K T E E+ P G G + P PR E Sbjct: 787 GYPGPRGVKGADGIRGLKGTKGEKGED------GFPGFKGDMGIKGDRGEIGPPGPRGED 840 Query: 172 QPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQA-S 230 P + P+ P P P + + P PG YP Q Sbjct: 841 GPEGPK-----------------GRGGPNGDPGPLGPPGEKGKLGVPGLPG-YPGRQGPK 882 Query: 231 GADSWPPAAENSFPGANF--------GVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHG 282 G+ +P FPGAN G P + P G R PRG++ + P G Sbjct: 883 GSIGFP-----GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGK---PGPKG 934 Query: 283 ASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQP 342 S PA G NGP Q +P GP P P P LP + GQ Sbjct: 935 NSGGDGPAGPPGERGPNGP------QGPTGFP------GPKGP-PGPPGKDGLPGHPGQR 981 Query: 343 G--GLNRHSDLSG--ALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQ--DGLGSTRG 396 G G + G + P P + H P PP Q GL G Sbjct: 982 GETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG-----PPGPPGEQGLPGLAGKEG 1036 Query: 397 P-----PSSLPQRHFPGQAYRASGVDTSPGPPDT-----ELAAPGPP-PARLPQLWDPTA 445 P+ LP + P G PGP PGPP PA P P Sbjct: 1037 TKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAG 1096 Query: 446 APYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLP 505 A GP+ G P P P P G++ LP Sbjct: 1097 A------AGPIGIPGRPGPQGPPGPAGEKGAPGEKG-------PQGPAGRDGLQGPVGLP 1143 Query: 506 FPAG--GPEWQGGSQGALGTAGKTPGPREK----LPAVRSSQG--GSPALFTYNGMTDPG 557 PAG GP + G +G +G G+ +K P QG G P +G P Sbjct: 1144 GPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPR 1203 Query: 558 AQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPAN 617 Q FG + P G P PP VG P P G P P Sbjct: 1204 GQQGLFG-QKGDEGPRGFPG--PPGPVGL--QGLPGPPGEKGETGDVGQMGPPGPPGPRG 1258 Query: 618 PSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLG 677 PS GP GP P E G P + EP LP P K G Sbjct: 1259 PSGAPG-ADGPQGPPGGIGNPGAVGEKGEPGEAGEP--GLPGEGGPPGPKGERGEKGESG 1315 Query: 678 AEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQLDVLLTCRQC 736 GA P + G G GFP P PP D+ D Sbjct: 1316 PSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD-------- 1367 Query: 737 DRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP-RVPADAHAGLLSHAK 795 + G SPGP G P P P + AG Sbjct: 1368 ----------------------DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405 Query: 796 TFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQS 855 G+A EG P +TG + A P P + L G+ Sbjct: 1406 EKGAKGEAGLEG--PPGKTGPIGPQGAPGKPGP-----------------DGLRGI---- 1442 Query: 856 DNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGD 915 P + + P GP GP LK +G E P + P + GD Sbjct: 1443 PGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGD 1502 Query: 916 RGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRA 975 RG P QG +G+Q G SG G Sbjct: 1503 RGLPG-------------------PQGSSGPKGEQ-----------GITGPSGPIGPPGP 1532 Query: 976 SGLRPRRNDGLGERPPPRPRRPRTQA--PGSRADPAPRVPRAAALPEETRSSRRRR 1029 GL P G + P P+ +A PG P P P P ++SR RR Sbjct: 1533 PGL-PGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP--PGEVIQPLPIQASRTRR 1585 Score = 88.6 bits (218), Expect = 1e-16 Identities = 194/782 (24%), Positives = 241/782 (30%), Gaps = 177/782 (22%) Query: 2 PGERPRGAPP--PTMTGDLQPRQVASSPGHPSQ--------PPLEDNTPATRTTKGAREA 51 PGE+ + P P G P+ PG P P + R G R Sbjct: 861 PGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGE 920 Query: 52 GGQAQAMELPEAQPRQARDGELKPPSLRG----QAPSSTPGKRGSPQTPPGRSPLQAPSR 107 G P + DG PP RG Q P+ PG +G P PPG+ L Sbjct: 921 RGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPG-PPGKDGLP---- 975 Query: 108 LAGRAEGSPPQRYILGIASSRTKPTLDET--PENPQLEAAQLPEVDTPQGPGT------- 158 G P QR G P P+ P E + E P PG Sbjct: 976 ------GHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029 Query: 159 ---------GAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAP- 208 G P GLP + P R P + P P PP P Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP---PGPPGPA 1086 Query: 209 GPPQSRGTS--------PLQPGSYPEYQASGADSWP-------PAAENSFPGANFGVP-P 252 G P RG + P +PG +G P PA + G G+P P Sbjct: 1087 GSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP-VGLPGP 1145 Query: 253 AEP--------------EPIPKGSRPG----GSPRGVSFQFPF--PALHGASTKPFPADV 292 A P EP KGS+ G P Q P P GA +P P Sbjct: 1146 AGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQ 1205 Query: 293 AGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLS 352 G G P+G GP P+ Q P P P +G+ G + + Sbjct: 1206 QGLFGQKGD-----EGPRGF-------PGPPGPVGLQGLPGP-PGEKGETGDVGQ----M 1248 Query: 353 GALSSPGAAHSAPRPFSDSLHKSLTKILPERPP-----------------SAQDGLGSTR 395 G PG + P +D P+ PP + + GL Sbjct: 1249 GPPGPPGPRGPSGAPGADG---------PQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEG 1299 Query: 396 GPPSSLPQRHFPGQA--YRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPG 453 GPP +R G++ A+G GPP + P P P P P P Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359 Query: 454 GPLAATRSMFFNGQP-SPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPE 512 GP GQ SPG PT P P G P PAG PE Sbjct: 1360 GPPGDKGDDGEPGQTGSPG-----------------PTGEPGPSGPPGKRGPPGPAG-PE 1401 Query: 513 WQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQ--V 570 + G +GA G AG P + P G P G+ P + G P Sbjct: 1402 GRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPP 1461 Query: 571 SPHGTPSLP-------------PPRVVG--------ASPSESPLPSPATNTAGSTCSSLS 609 P G P LP P ++G + LP P ++G Sbjct: 1462 GPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP-QGSSGPKGEQGI 1520 Query: 610 PMSSSPANPSSEESQLPGPLGPSAF--FHPPTHPQ-ETGSPFPSPEPPHSLPTHYQPEPA 666 S P P LPGP GP PT P+ E G P P P PP QP P Sbjct: 1521 TGPSGPIGPPGPPG-LPGPPGPKGAKGSSGPTGPKGEAGHPGP-PGPPGPPGEVIQPLPI 1578 Query: 667 KA 668 +A Sbjct: 1579 QA 1580 Score = 82.4 bits (202), Expect = 8e-15 Identities = 192/768 (25%), Positives = 247/768 (32%), Gaps = 143/768 (18%) Query: 1 MPG-ERPRGAP----PPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQA 55 MPG + P G P PP G P G+P P R KG + G+ Sbjct: 755 MPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG-PRGVKGADGIRGLKGTKGEKGED 813 Query: 56 QAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGS 115 + GE+ PP RG+ P RG P PG PL G Sbjct: 814 GFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPG--PL-----------GP 860 Query: 116 PPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAA 175 P ++ LG+ P + P + +G G G P +PG PR + P Sbjct: 861 PGEKGKLGVPGLPGYP--GRQGPKGSIGFPGFPGANGEKG-GRGTPGKPG-PRGQRGPTG 916 Query: 176 E--ELGFHRCFQE--------------PPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPL 219 E G + PP P+ P P P P + P Sbjct: 917 PRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPG 976 Query: 220 QPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEP--EPIPKGSRPGGSPRGVSFQFPF 277 PG E G + PP PG V P P E P G R P G + Sbjct: 977 HPGQRGETGFQG-KTGPPGP----PGV---VGPQGPTGETGPMGERGHPGPPGPPGEQGL 1028 Query: 278 PAL---HGASTKPFPADVAGHAFTNGPLVFAFHQPQG-AWPEEAVGTGPAYPLPTQPAPS 333 P L G P PA + G P + F +G P A+G P P P+ Sbjct: 1029 PGLAGKEGTKGDPGPAGLPGK--DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPA 1086 Query: 334 PLPCYQGQPGGLNRHSDLSGALSSPG--AAHSAPRPFSDSLHKSLTKILPERPPSAQDGL 391 P +G G +G + PG P P + K + P+ +DGL Sbjct: 1087 GSPGERGPAGA-------AGPIGIPGRPGPQGPPGPAGE---KGAPGEKGPQGPAGRDGL 1136 Query: 392 GSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTP 451 G P P G D G E+ PG ++ + P PT Sbjct: 1137 QGPVGLPG-------PAGPVGPPGEDGDKG----EIGEPGQKGSKGDK--GEQGPPGPTG 1183 Query: 452 PGGPLAATRSMFFNGQPSP-GQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGG 510 P GP+ +G+P P GQ+ Q P P P G L LP P G Sbjct: 1184 PQGPIGQPGPSGADGEPGPRGQQGLFGQKG-----DEGPRGFPGPPGPVGLQGLPGPP-G 1237 Query: 511 PEWQGGSQGALGTAGKTPGPR--EKLPAVRSSQG-----GSPALFTYNGMTDPGAQPLFF 563 + + G G +G G PGPR P QG G+P G +P Sbjct: 1238 EKGETGDVGQMGPPG-PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP 1296 Query: 564 GVAQP-----------QVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMS 612 G P + P G P P+ G + P SP Sbjct: 1297 GEGGPPGPKGERGEKGESGPSGAAGPPGPK--GPPGDDGPKGSPGP-------------V 1341 Query: 613 SSPANPSSEESQLPGPLGPSAFFHPP------THPQETGSPFPSPEPPHSLPTHYQPEPA 666 P +P PG GP+ PP P +TGSP P+ EP S P + P Sbjct: 1342 GFPGDPGP-----PGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPG 1396 Query: 667 KAFPFPADG-LGAEGAFQCLEETPFPHEGP--EVGRGGLQGFPRAPPP 711 A P G GA+G EGP + G G QG P P P Sbjct: 1397 PAGPEGRQGEKGAKGEAGL--------EGPPGKTGPIGPQGAPGKPGP 1436 Score = 79.7 bits (195), Expect = 5e-14 Identities = 331/1471 (22%), Positives = 425/1471 (28%), Gaps = 340/1471 (23%) Query: 30 PSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPG- 88 P P +D P T+G E G+ E P + + E P +A T Sbjct: 249 PDTPQSQDPNPDEYYTEGDGE--GETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETTEV 306 Query: 89 KRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQL-----E 143 TP +P+ S AG+ E +GI P+ D +P E Sbjct: 307 PEELTPTPTEAAPMPETSEGAGKEED-------VGIGDYDYVPSEDYYTPSPYDDLTYGE 359 Query: 144 AAQLPEVDTPQGPGTGAPLRPGLPRTEAQPA------AEELGFHRCFQEPPSSFTSTNYT 197 + P+ T G G P + PA A++L F E NY Sbjct: 360 GEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGE--FTEETIRNLDENYY 417 Query: 198 SP----SATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPA 253 P +++P PG P ++ T + G G P E PG PP Sbjct: 418 DPYYDPTSSPSEIGPGMPANQDT--IYEGIGGPRGEKGQKGEPAIIE---PGMLIEGPPG 472 Query: 254 EPEPIPKGSRPG--------GSP--RGVSFQFPFPALHGASTKPFPADV----------A 293 P PG G P RG + P L GA P P Sbjct: 473 PEGPAGLPGPPGTMGPTGQVGDPGERGPPGR---PGLPGADGLPGPPGTMLMLPFRFGGG 529 Query: 294 GHAFTNGPLVFAFHQPQGAWPEEA--VGTGPAYPLPTQPAPSPLPC-----YQGQPGGLN 346 G A + GP+V A A ++A GPA P+ P P+ +G+PG + Sbjct: 530 GDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVG 589 Query: 347 RHSDLSGALSSPGAAHSAPR-----------------PFSDSLHKSLTKILPERPPSAQD 389 G PG A R P D L + E+ Sbjct: 590 PQGP-RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDP 648 Query: 390 GLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGP-----PDTELAAPGPP----------- 433 G GPP +R G+ G+ PGP P PGPP Sbjct: 649 GPSGPPGPPGDDGERGDDGEV-GPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGP 707 Query: 434 ---------PARLPQLWDPTAAPYPTPPG--GPLAATRSMFFNGQPS------------- 469 P Q +P A P P G GP + G P Sbjct: 708 KGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK 767 Query: 470 ---PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLP-------------FPA----- 508 PG++ P PQ P P P G++ + FP Sbjct: 768 EGPPGEK----GGQGPPGPQG-PIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM 822 Query: 509 -----------GGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPG 557 GP + G +G G G P P + G P L Y G P Sbjct: 823 GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK 882 Query: 558 AQPLFFGV--AQPQVSPHGTPSLPPPR----VVGASPSESPL-----PSPATNTAGSTCS 606 F G A + GTP P PR G P P P N+ G Sbjct: 883 GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGD--- 939 Query: 607 SLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPA 666 PA P E GP GP+ F P P G P T +Q + Sbjct: 940 -------GPAGPPGERGP-NGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991 Query: 667 KAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQ 726 P P +G +G P GP G +G P P P Sbjct: 992 P--PGPPGVVGPQG--------PTGETGPM----GERGHPGPPGPPGEQ----------- 1026 Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPS---PPAAPRVP 783 GL K+G + PGP GLP PP P Sbjct: 1027 ---------------------------GLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFP 1059 Query: 784 ADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL--PSLAATPFPLPASDLDMEDDAKLD 841 D GL L G+ G P + P+ AA P +P Sbjct: 1060 GDR--GLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP---------- 1107 Query: 842 SLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPL 901 P+ GP+GP+ L+ G+ P P Sbjct: 1108 ---------------GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGL-PGPAGPVGP 1151 Query: 902 PAATPDP-QTPRPGDRGCPA----RGRP-KTRSLGLAPTEADAPSQGRQQRRGKQLKLFR 955 P D + PG +G +G P T G + + G RG+Q LF Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ-GLFG 1210 Query: 956 KDLDSGGAAEGSGSGGGGRASGLRPRRNDG----LGERPPPRPRRPR--TQAPGSRADPA 1009 + D G G G P G +G+ PP P PR + APG+ Sbjct: 1211 QKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQG 1270 Query: 1010 PRV----PRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYD 1065 P P A E + LP P K G G+ Sbjct: 1271 PPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGE----------------- 1313 Query: 1066 FASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQ----EAGGD 1121 + S P P+GP G G V P P +P A + + G D Sbjct: 1314 -SGPSGAAGPPGPKGPP--GDDGPKGSPGPVGFPGDP--GPPGEPGPAGQDGPPGDKGDD 1368 Query: 1122 GAPANPEEPGGS-RPGPGRSPQARGP-------SRSLETGAAAREG-----GPKCADRPS 1168 G P PG + PGP P RGP R E GA G G P Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428 Query: 1169 VAPKDP-------LQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE------ 1215 AP P + P E P D P P DS E Sbjct: 1429 GAPGKPGPDGLRGIPGPVG-EQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGL 1487 Query: 1216 -ALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLL 1274 L PP GE G GL P+ + + G PSG + P G PG Sbjct: 1488 IGLIGPPGE-QGEKG-DRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAK 1545 Query: 1275 G--GPGGTQAPVSHNSKDPPARQPGEFLAPV 1303 G GP G + H P PGE + P+ Sbjct: 1546 GSSGPTGPKGEAGHPGPPGPPGPPGEVIQPL 1576 Score = 67.0 bits (162), Expect = 3e-10 Identities = 132/497 (26%), Positives = 166/497 (33%), Gaps = 88/497 (17%) Query: 3415 GGRQPFAFRGVRRP-GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473 G + P F G + P G PG+ L G P +R G PG PP P Sbjct: 952 GPQGPTGFPGPKGPPGPPGKDG--LPGH-PGQRGETGFQGKTGPPG----PPGVVGPQGP 1004 Query: 3474 EGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCE----------LPSNHQECP 3523 G E P +G P P + + G E LP Sbjct: 1005 TG----------ETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDG--- 1051 Query: 3524 PPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQ--QALPLGASLP-----RP 3576 PP L FP RG GAL NE PG PGP + P GA+ P RP Sbjct: 1052 PPGLRGFPG----DRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107 Query: 3577 GARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGT 3636 G +G +G++ APG +G P D L + V G G Sbjct: 1108 GPQGPPGP--------AGEKGAPGEKGPQGPAG--RDGLQGPVGLPGPAGPVGPPGEDGD 1157 Query: 3637 FHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP 3696 KG +P G + S D+ P P P+ +G PG E G P Sbjct: 1158 --KGEIGEP-GQKGSKGDKGEQGPPG-----PTGPQGPIGQ--PGPSGADGEPG-----P 1202 Query: 3697 KAKPGPSSQ-GSGSPR--PGTKTGGGSQPQPASGQLQSETATT-------PAKPSFPSRS 3746 + + G Q G PR PG G Q P + ET P P PS + Sbjct: 1203 RGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGA 1262 Query: 3747 PAPERLPARAQAKSCTKGPREAGEQGPHGSLG-PKEKGESSTKRKKGQVPGPARSESVGS 3805 P + E GE G G G P E G K ++G+ + ES S Sbjct: 1263 PGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGE-----KGESGPS 1317 Query: 3806 FGRAPSAPDKPPRTPRKQATPSRV-LPTKPKPNSQNKPR----PPPSEQRKAEPGHTQRK 3860 P P PP + +P V P P P + P PP + EPG T Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377 Query: 3861 DRLGKAFPQGRPLLRPP 3877 G+ P G P R P Sbjct: 1378 GPTGEPGPSGPPGKRGP 1394 Score = 65.1 bits (157), Expect = 1e-09 Identities = 229/964 (23%), Positives = 293/964 (30%), Gaps = 173/964 (17%) Query: 1678 GLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSL 1737 GL +G PP + QPGP+ + G + P + P + Q + Sbjct: 682 GLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA---- 737 Query: 1738 RLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAP-DLAFQGDGAP--PLDATWP 1794 + P ++G L +PG P GA P G P P + QG P P+ P Sbjct: 738 -IGPPGEKGP-LGKPGLPGMP--GADGPP--GHPGKEGPPGEKGGQGPPGPQGPIGYPGP 791 Query: 1795 FGASPSHAAQG--HSAGRAGGHLHPTAGRPGFEGN--------EFAPAGASSLTAPRGRE 1844 G + +G + G G G PGF+G+ E P G P G + Sbjct: 792 RGVKGADGIRGLKGTKGEKGED-----GFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPK 846 Query: 1845 AWLVPVPSPACVSNTHPSRRSQDPALSP-PIRQLQLPGPGVAKSKDGILGLQELTPAAQS 1903 P P + + P L P RQ GP + G G + Sbjct: 847 GRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ----GPKGSIGFPGFPGANGEKGGRGT 902 Query: 1904 PPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEK 1963 P + P G G T GP +G G +T P G+ G DG G G+ Sbjct: 903 PGKPGPRGQRGPT--------GP-RGERGPRGITGKPGPKGNSGG---DGPAGPPGERGP 950 Query: 1964 TQGQGTANQLQPENGVSPGGTDN-------HASVNASPKTALTGPTEGAVLLEKCKGSRA 2016 QG P+ P G D KT GP G V + G Sbjct: 951 NGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPP-GVVGPQGPTGETG 1009 Query: 2017 AMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPA 2076 M + P PP P E L + G++G P A PG + P G Sbjct: 1010 PMGERGH----PGPPGPPGEQ---GLPGLAGKEGTKG-DPGPAGLPGKDGPPGLRGFP-- 1059 Query: 2077 PSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPS-RAQGGLGGQL--PASPSCRDPPG 2133 GD P P A + + GP P SP R G G + P P + PPG Sbjct: 1060 ---GDRGL--PGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPG 1114 Query: 2134 PQQLLACSPAWAPLEEA--DGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEG 2191 P P A DG+Q PV PP + E +G Sbjct: 1115 PAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEP------GQKG 1168 Query: 2192 SPLEDPSSWPPGSVSAV-TCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVS 2250 S + PPG G + D P ++ L+ G G Sbjct: 1169 SKGDKGEQGPPGPTGPQGPIGQPGPSGADGE---PGPRGQQGLFGQKGDEGPRGFPGPPG 1225 Query: 2251 PSVAVRATGLSSTP-----TGDEAQAGR-GLPGPDPQSRGAPPHTNPDRMPRGHSSYSPS 2304 P V GL P TGD Q G G PGP S GAP P P G + P Sbjct: 1226 P---VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPS-GAPGADGPQGPPGGIGN--PG 1279 Query: 2305 NTARLGHREGQAVTAVPTE--PPTLQG-------------AGPDSPACLEGEMGTSSKE- 2348 G +P E PP +G AGP P G+ G Sbjct: 1280 AVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPG 1339 Query: 2349 ----PEDPGTP----------------ETGRSGATKMPRVTC-PSTGLGLGRTTAPSSTA 2387 P DPG P + G G T P T P G+ P Sbjct: 1340 PVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAG 1399 Query: 2388 SDFQSDSPQSHRNASHQTPQGD--PLGPQDL--KQRSRGYKKKPAST-ENGQWKGQAPHG 2442 + + + A + P G P+GPQ K G + P E G P G Sbjct: 1400 PEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDG 1459 Query: 2443 PVTCEVCAASFRSGPGLSRHKARKHRPH-------PGAPAEPSPAALPAQQ--------- 2486 P + G S K K P PG E LP Q Sbjct: 1460 PPG-PMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ 1518 Query: 2487 ----PLEPLAQKCQP-----PRKKSHRVS----------GKERPNHSRGDPSHVTQPPPA 2527 P P+ P P K + S G P G P V QP P Sbjct: 1519 GITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPI 1578 Query: 2528 QGSK 2531 Q S+ Sbjct: 1579 QASR 1582 Score = 64.7 bits (156), Expect = 2e-09 Identities = 290/1262 (22%), Positives = 377/1262 (29%), Gaps = 262/1262 (20%) Query: 310 QGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFS 369 +GA EE VG G +P++ +P P G + D + PGA P + Sbjct: 325 EGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQP---TDPGAGAEIPTSTA 381 Query: 370 DSLHKSLTKILPERPPSAQDGLGSTRGP-------------------PSSLPQRHFPGQA 410 D+ + S P PP +G G P+S P PG Sbjct: 382 DTSNSSN----PAPPPG--EGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMP 435 Query: 411 YRASGVDTSPGPPDTELAAPGPPPARLPQLW------DPTAAPYPTPPGGPLAATRSMFF 464 + G P E G P P + A P PPG + T + Sbjct: 436 ANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPG-TMGPTGQVGD 494 Query: 465 NGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTA 524 G+ P R LP + LP P P M ML PF GG GS+G + +A Sbjct: 495 PGERGPPGRPGLPGADGLPGP---------PGTMLML---PFRFGGGG-DAGSKGPMVSA 541 Query: 525 GKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGV-AQP-QVSPHGTPSLPPPR 582 ++ + L R + G G P P G+ +P V P G PR Sbjct: 542 QESQA-QAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQG------PR 594 Query: 583 VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEE--SQLPGPLG------PSAF 634 V P + P AGS + P + P + + LPG G PS Sbjct: 595 GVQGPPGPAGKPG-RRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSG- 652 Query: 635 FHPPTHPQETGSPFPSPEP-PHSLPTHYQPEPA---KAFPFPADGLGAEGAFQCLEETPF 690 PP P + G E P LP P K P P G G ++ P Sbjct: 653 --PPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG----MDGQPG 706 Query: 691 PHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHR 750 P G G QG P P Sbjct: 707 PK-----GNVGPQGEPGPPGQQ-------------------------------------- 723 Query: 751 QFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHA-GLLSHAKTFLLAGDAQAEGKD 809 G A+ G Q + GPPG P P +P A G H G+ +G Sbjct: 724 ---GNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPP 780 Query: 810 DPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFA 869 P P L K + M + D EI Sbjct: 781 GPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIG-------- 832 Query: 870 DEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSL 929 P GPRG K + G + P PL + PG G P R PK S+ Sbjct: 833 ---PPGPRGEDGPEGPKGRGGPNGD---PGPLGPPGEKGKLGVPGLPGYPGRQGPKG-SI 885 Query: 930 GLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDG---- 985 G +G + GK ++ +G E G G+ P+ N G Sbjct: 886 GFPGFPGANGEKGGRGTPGKPGPRGQRG-PTGPRGERGPRGITGKPG---PKGNSGGDGP 941 Query: 986 ---LGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042 GER P P+ P T PG + P P + LP R Sbjct: 942 AGPPGERGPNGPQGP-TGFPGPKGPPGP--------------PGKDGLPGHPGQRGETGF 986 Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVEL 1098 G G +V + E E P P G PG G+ G L Sbjct: 987 QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGL 1046 Query: 1099 TQGPREDEPQKPR-----KAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL--- 1150 P +D P R + G G N PG PGP SP RGP+ + Sbjct: 1047 ---PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP--PGPAGSPGERGPAGAAGPI 1101 Query: 1151 ----------ETGAAAREGGPKCADRPSVAPKDPLQVPTNTET---------SEETRPSL 1191 G A +G P A +D LQ P + + + Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI 1161 Query: 1192 DFP-QEAKEPETAEESAPDSTEFTEALRSP-PAACAGEMG-------------------- 1229 P Q+ + + E+ P T + P P+ GE G Sbjct: 1162 GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFP 1221 Query: 1230 ---ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSH 1286 GL PP + +TG G P G S PG G PGG P + Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281 Query: 1287 NSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQ 1346 K +PGE P P P P + G A P G P GP+ Sbjct: 1282 GEKG----EPGEAGEP-GLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKG-PPGDDGPK 1335 Query: 1347 PYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPP 1406 SP F G G P P+ +D PP DGE + P P P Sbjct: 1336 --GSPGPVGFPGDPGPPG------EPGPAGQDGPPGDKG---DDGEPGQTGSPG-PTGEP 1383 Query: 1407 GTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPS 1466 G + PG+ P P P R G A ++GL PP KT P Sbjct: 1384 GPS-GPPGKRGPPG--------PAGPEGR-----QGEKGAKGEAGL----EGPPGKTGPI 1425 Query: 1467 DP 1468 P Sbjct: 1426 GP 1427 Score = 63.2 bits (152), Expect = 5e-09 Identities = 136/535 (25%), Positives = 170/535 (31%), Gaps = 66/535 (12%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAP---GPGEDRPP-PRGSSPILSEGSLPALLHL 3483 PG G A +P + PG A PGE P P G + LP Sbjct: 1089 PGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGP--- 1145 Query: 3484 CSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADG----RG 3539 V P G + P + +G + P P P P+ ADG RG Sbjct: 1146 AGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG-ADGEPGPRG 1204 Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAE----GKRAPLVFSGK 3595 L G PG PGP+ Q LP PG +G+ + G P G Sbjct: 1205 QQGLFGQKGDEGPRGFPGPPGPVGLQGLP-----GPPGEKGETGDVGQMGPPGPPGPRGP 1259 Query: 3596 RRAPGARGRCAPDHFQEDHLLQKEK----EVSSSHMVSEGGP---------RGTFHKGSA 3642 APGA G P + EK E + EGGP +G A Sbjct: 1260 SGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGA 1319 Query: 3643 TKPAGCQSSSKDRSAASTPSKALKFPV------HPRKAVGSLAPGELARGTENGMKPAT- 3695 P G + D +P + FP P A PG+ E G + Sbjct: 1320 AGPPGPKGPPGDDGPKGSPGP-VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPG 1378 Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQP-ASGQLQSETA---TTPAKPSFPSRSPAPER 3751 P +PGPS PG G Q + A G+ E T P P P P+ Sbjct: 1379 PTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG 1438 Query: 3752 LPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPG-------PARS 3800 L P G GP G +GP KG+S K +KG PG P Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGH-PGLIGLIGPPGEQ 1497 Query: 3801 ESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRK 3860 G G P+ + PS P P P P PP + K G T K Sbjct: 1498 GEKGDRGLPGPQGSSGPKGEQGITGPSG--PIGP-PGPPGLPGPPGPKGAKGSSGPTGPK 1554 Query: 3861 DRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAEAQSDLLSQLFGQRLTGF 3915 G P G P PP G + T R +A S LL G+ + Sbjct: 1555 GEAGHPGPPGPP--GPP--GEVIQPLPIQASRTRRNIDA-SQLLDDGNGENYVDY 1604 Score = 62.4 bits (150), Expect = 9e-09 Identities = 275/1216 (22%), Positives = 356/1216 (29%), Gaps = 242/1216 (19%) Query: 1648 QEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRP--PQDVCLPEPSKQPGPQL 1705 Q L P P G PV G+ GL GD P P+ V P PGP Sbjct: 552 QARLALRGPAGPMGLTGRPGPVGPPGSG--GLKGEPGDVGPQGPRGVQGP-----PGPAG 604 Query: 1706 DAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAP 1765 G + D P + D L LP E+ G +PG + P G P Sbjct: 605 KPGRRGRAGSDGARGMP-GQTGPKGDRGFDGLAGLPGEK--GHRGDPGPSGPP--GPPGD 659 Query: 1766 EAFGSPAVHLAPDLAFQGDGAP-----PLDATWPFGASPSHAAQGHSAGRAGGHLHPTAG 1820 + + P G+ P P P G G + G Sbjct: 660 DGERGDDGEVGPR-GLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPG 718 Query: 1821 RPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLP 1880 PG +GN GA L P+G A+ PP + L Sbjct: 719 PPGQQGNP----GAQGLPGPQG--------------------------AIGPPGEKGPLG 748 Query: 1881 GPGVA--KSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTT 1938 PG+ DG G P + PP G +G G + +G G + Sbjct: 749 KPGLPGMPGADGPPG----HPGKEGPP--GEKGGQGPPGPQGPIGYPGPRGVKGADGIRG 802 Query: 1939 LPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTAL 1998 L G + DG G G +G P P G N P L Sbjct: 803 LKGTKGEK---GEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGP-L 858 Query: 1999 TGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPER 2058 P E KG L P P A+ G G TP + Sbjct: 859 GPPGE--------KGKLGVPGLPGY----PGRQGPKGSIGFPGFPGANGEKGGRG-TPGK 905 Query: 2059 ASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGL 2118 G P G+ P P G + P P +G Sbjct: 906 PGPRGQRGPTGPRGER-------------GPRGITGKPGPKGNSGGDGPAGPPGE-RGPN 951 Query: 2119 GGQLPAS-PSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCD 2177 G Q P P + PPGP P L G + T + P PP + P Sbjct: 952 GPQGPTGFPGPKGPPGP-------PGKDGLPGHPGQRGETGFQGKTGPPGPPGVV-GPQG 1003 Query: 2178 PKEALAGCLLQGEGSPL-EDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWES 2236 P GE P+ E PPG G K+ T P + Sbjct: 1004 PT---------GETGPMGERGHPGPPGPPGEQGLP--GLAGKEGTKGDPGPAGLPGKDGP 1052 Query: 2237 PGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPR 2296 PG P G P V A GL G+E G P P RG P +P Sbjct: 1053 PGLRGFPGDRGLPGP---VGALGLK----GNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105 Query: 2297 GHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGA----GPDSPACLEGEMGTSSKEPEDP 2352 P A G+ P LQG GP P GE G + E Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165 Query: 2353 GTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQT----PQG 2408 G G P T P +G P + +D + P+ + Q P+G Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIG-----QPGPSGADGEP-GPRGQQGLFGQKGDEGPRG 1219 Query: 2409 --DPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPV-TCEVCAASFRSGP--GLSRHK 2463 P GP L+ +K + + GQ P GP A GP G+ Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG 1279 Query: 2464 ARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHR-VSGKERPNHSRGDPSHVT 2522 A + PG EP LP + PP K R G+ P+ + G P Sbjct: 1280 AVGEKGEPGEAGEPG---LPGEGG---------PPGPKGERGEKGESGPSGAAGPPG--P 1325 Query: 2523 QPPPA----QGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQ 2578 + PP +GS + PG P PP PA + P + D+ P Q Sbjct: 1326 KGPPGDDGPKGSPGPVGFPGDPG-----PPGEPG-------PAGQDGPPGDKGDDGEPGQ 1373 Query: 2579 AEKR--------EGRRWRREPTVDSPSHSEGKSNKKRGK----LRGRRLREESILPVSAD 2626 G +R P P+ EG+ +K K L G + I P Sbjct: 1374 TGSPGPTGEPGPSGPPGKRGPP--GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGP---- 1427 Query: 2627 VISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEAL 2686 G +P P P + G P DG P PG ++G + E Sbjct: 1428 ---QGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPG-LKGDSGPKGEKG 1483 Query: 2687 CAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEP 2746 G G PPG++ G+KG RG GP + S P Sbjct: 1484 HPGLIGLIGPPGEQ-----------------GEKGD--RGLPGP----------QGSSGP 1514 Query: 2747 AEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGP 2806 + E+G+ T P GP+G P P P P G GP Sbjct: 1515 ---------KGEQGI----TGPSGPIGPPGPPGLPG-----------PPGPKGAKGSSGP 1550 Query: 2807 EGPTPDASGSSAKDPP 2822 GP +A PP Sbjct: 1551 TGPKGEAGHPGPPGPP 1566 Score = 60.8 bits (146), Expect = 2e-08 Identities = 118/473 (24%), Positives = 157/473 (33%), Gaps = 67/473 (14%) Query: 3423 RGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLH 3482 RGV+ P P K P +R R G+ PG+ P +G LP Sbjct: 594 RGVQGPPGPAGK--------PGRRGRAGSDGARGMPGQTGP--KGDRGFDGLAGLPGEKG 643 Query: 3483 LCSEVAPSTTKGWP-ETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDC 3541 + PS G P + ER D P RG + P P P G Sbjct: 644 HRGDPGPSGPPGPPGDDGERGDDGEVGP-RGLPGEPGPRGLLGPKGPPGPPGPP---GVT 699 Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAEGKRAPLVFSGKRRAPG 3600 +DG N G PGP QQ P LP P GA G G++ PL G PG Sbjct: 700 GMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPP--GEKGPLGKPGLPGMPG 757 Query: 3601 ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEG--GPRGTFHKGSATKPAGCQSSSKDRSAA 3658 A G P H KE +G GP+G P G + + R Sbjct: 758 ADG--PPGH--------PGKEGPPGEKGGQGPPGPQGPI---GYPGPRGVKGADGIRGLK 804 Query: 3659 STPSKALK--FPVHPRKAVGSLAPGELA-RGTENGMKPATPKAKPGPSSQGSGSPRPGTK 3715 T + + FP G++ +G + P P+ + GP P + Sbjct: 805 GTKGEKGEDGFPGFK---------GDMGIKGDRGEIGPPGPRGEDGPEG-------PKGR 848 Query: 3716 TGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL--PARAQAKSCTKGPREAGEQGP 3773 G P P + P P +P R + P A G G+ GP Sbjct: 849 GGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGP 908 Query: 3774 HGSLGPK-EKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPT 3832 G GP +GE + G+ PGP + G G A ++ P P+ PT Sbjct: 909 RGQRGPTGPRGERGPRGITGK-PGPKGNS--GGDGPAGPPGERGPNGPQG--------PT 957 Query: 3833 KPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHG 3885 P + P PP + PG GK P G P + P+ T G Sbjct: 958 G-FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009 Score = 60.5 bits (145), Expect = 3e-08 Identities = 243/1021 (23%), Positives = 304/1021 (29%), Gaps = 187/1021 (18%) Query: 1624 GRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAG----ASKTGL 1679 GRPG P PG L + + P PRG P K G A G Sbjct: 568 GRPGPVGP------PGSGGL----KGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGA 617 Query: 1680 CQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739 G + P D + PG + G P P + + E R Sbjct: 618 RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPG----PPGDDGERGDDGEVGPRG 673 Query: 1740 LPCEQ--RGGFLPE--PGTADQPH----RGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDA 1791 LP E RG P+ PG P G P P+ P P GA L Sbjct: 674 LPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPG 733 Query: 1792 TWPFGASPSHAAQGHSAGRAGGHLHPTA-GRPGFEGNEFAPAGASSLTAPRGREAWLVPV 1850 P GA +G G+ G P A G PG G E P G P G + + Sbjct: 734 --PQGAIGPPGEKG-PLGKPGLPGMPGADGPPGHPGKE-GPPGEKGGQGPPGPQG-PIGY 788 Query: 1851 PSPACVSNTHPSRRSQ----------------DPALSPPIRQLQLPGPGVAKSKDGILGL 1894 P P V R + D + ++ PGP + +DG G Sbjct: 789 PGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGP---RGEDGPEGP 845 Query: 1895 QELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGH 1954 + P + P G +G G QG G + P G + G G Sbjct: 846 KGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGK 905 Query: 1955 WGLLGQAEKT--QGQ----GTANQLQPE---NGVSPGGTDNHASVNA-SPKTALTGP--- 2001 G GQ T +G+ G + P+ G P G N T GP Sbjct: 906 PGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGP 965 Query: 2002 --TEGAVLLEKCKGSRAAMSLQEEAEPT-----------------------PSPPSPNRE 2036 G L G R Q + P P PP P E Sbjct: 966 PGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGE 1025 Query: 2037 SLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMP 2096 L + G++G P A PG + P G GD P P A + Sbjct: 1026 Q---GLPGLAGKEGTKG-DPGPAGLPGKDGPPGLRG-----FPGDRG--LPGPVGALGLK 1074 Query: 2097 CSLGPLPREDPLTSP-SRAQGGLGGQ--LPASPSCRDPPGPQQLLACSPAWAPLEEA--D 2151 + GP P SP R G G +P P + PPGP P A D Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1134 Query: 2152 GVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAV-TC 2210 G+Q PV PP + E +GS + PPG Sbjct: 1135 GLQGPVGLPGPAGPVGPPGEDGDKGEIGEP------GQKGSKGDKGEQGPPGPTGPQGPI 1188 Query: 2211 THSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTP-----T 2265 G + D P ++ L+ G G P V GL P T Sbjct: 1189 GQPGPSGADGE---PGPRGQQGLFGQKGDEGPRGFPGPPGP---VGLQGLPGPPGEKGET 1242 Query: 2266 GDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTE- 2323 GD Q G G PGP S GAP P P G +P G +P E Sbjct: 1243 GDVGQMGPPGPPGPRGPS-GAPGADGPQGPPGGIG--NPGAVGEKGEPGEAGEPGLPGEG 1299 Query: 2324 -PPTLQG-------------AGPDSPACLEGEMGTSSKE-----PEDPGTP-ETGRSGAT 2363 PP +G AGP P G+ G P DPG P E G +G Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359 Query: 2364 KMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGY 2423 P G P T S + P + P G P GP+ +Q +G Sbjct: 1360 GPPG--------DKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPG-PAGPEG-RQGEKGA 1409 Query: 2424 KKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHP----GAPAEPSP 2479 K + A E K P GP + PG + P P G P P P Sbjct: 1410 KGE-AGLEGPPGK-TGPIGP----------QGAPGKPGPDGLRGIPGPVGEQGLPGSPGP 1457 Query: 2480 AALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHV--TQPPPAQGSKEVLRAP 2537 P P+ P K G P +G P + PP QG K P Sbjct: 1458 DGPPG-----PMGPPGLPGLK------GDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1506 Query: 2538 G 2538 G Sbjct: 1507 G 1507 Score = 58.5 bits (140), Expect = 1e-07 Identities = 305/1308 (23%), Positives = 382/1308 (29%), Gaps = 304/1308 (23%) Query: 875 GPRGPSS--GHPLKSKAGVTPESKAPPPLPAATPDP--------QTPRPGDRGCPAR-GR 923 GPRG G P + G+ E P PA P P Q PG+RG P R G Sbjct: 447 GPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGL 506 Query: 924 PKTRSLGLAPTE-----------ADAPSQGRQ---QRRGKQLKLFRKDLDSGGAAEGSGS 969 P L P DA S+G Q Q L + L G A G Sbjct: 507 PGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGL 566 Query: 970 GGGGRASGLRPRRNDGLGERP-------------PPRP-----RRPRTQAPGSRADPAPR 1011 G R + P + GL P PP P RR R + G+R P Sbjct: 567 TG--RPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQT 624 Query: 1012 VPRA-------AALPEET--RSSRRRRLPP--------RKDPRKRKARG--GAWGKELIL 1052 P+ A LP E R PP R D + RG G G +L Sbjct: 625 GPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLL 684 Query: 1053 KIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRK 1112 + PP PG G G+ + V QG Q+ Sbjct: 685 -----------------GPKGPPGPPGPPGVTGMDGQPGPKGNVG-PQGEPGPPGQQGNP 726 Query: 1113 AARQEAGGDGAPANPEEPGG-SRPGPGRSPQARGPSRSLETGAAAREGGP--KCADRPSV 1169 A+ G GA P E G +PG P A GP G +EG P K P Sbjct: 727 GAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPP-----GHPGKEGPPGEKGGQGPP- 780 Query: 1170 APKDPLQVP----------------TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEF 1213 P+ P+ P T E E+ P K E P Sbjct: 781 GPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRG--EIGPPGPRG 838 Query: 1214 TEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273 + P G PG P PP + G P G P GS PG Sbjct: 839 EDGPEGPKGR--GGPNGDPG---PLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGA 893 Query: 1274 LGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPK--PSVLSSKISSFGCDPAGF 1331 G GG P K P Q G P P+ K +S G PAG Sbjct: 894 NGEKGGRGTP----GKPGPRGQRGP-----TGPRGERGPRGITGKPGPKGNSGGDGPAG- 943 Query: 1332 NRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDG 1391 P ++GP P F GPK P P +D P Q G Sbjct: 944 -------PPGERGPNGPQGPTG--FPGPKG---------PPGPPGKDGLPGHPG---QRG 982 Query: 1392 EDAGSLEPQLPRSPPG-------TAETEP-GRAASPPTLESSSLFPDLPVDRFDPPLYGS 1443 E G P PPG T ET P G P P P ++ P L G Sbjct: 983 E-TGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP-------PGPPGEQGLPGLAGK 1034 Query: 1444 LSANRD---SGLPFACADPPQKTVPSD----PPYPSFLLLEEVSPMLPSHFPDLSGGKVL 1496 D +GLP P + P D P + L P P P +G Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP---PGPAGS--- 1088 Query: 1497 SKTCPPERTVVPGAAP-SLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRG 1555 P ER A P +PG+ +G Sbjct: 1089 ----PGERGPAGAAGPIGIPGR---------------------------------PGPQG 1111 Query: 1556 APRELAEAESVGRVELGTGTEPPSQRRTCQATV----------PHEDTFSAADLTRVGES 1605 P E + G G + P+ R Q V P + ++ G+ Sbjct: 1112 PPGPAGEKGAPGE----KGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQK 1167 Query: 1606 TAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLV-SGAPFSPRGANF 1664 + + E QG G P A PG P Q+ L PRG Sbjct: 1168 GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG-----PRGQQGLFGQKGDEGPRGF-- 1220 Query: 1665 HFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKN 1724 P GL G+ DV P PGP+ +G+ P N Sbjct: 1221 ---PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGN 1277 Query: 1725 KEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAP------- 1777 A + GG P ++ +G P P P Sbjct: 1278 PGAVGEKGEPGEAGEPGLPGEGG--PPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPK 1335 Query: 1778 ----DLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAG 1833 + F GD PP P A Q G G G PG G+ P G Sbjct: 1336 GSPGPVGFPGDPGPP--------GEPGPAGQDGPPGDKGDD-----GEPGQTGSP-GPTG 1381 Query: 1834 ASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPA-LSPPIRQLQLPGPGVAKSKDGIL 1892 + P G+ P PA + ++ A L P + GP A K G Sbjct: 1382 EPGPSGPPGKRG----PPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD 1437 Query: 1893 GLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEAD 1952 GL+ + P V GL G GP G PG + LP + G Sbjct: 1438 GLRGI------PGPVGEQGLPGSP--------GP-DGPPGPMGPPGLPGLKGDSGPKGEK 1482 Query: 1953 GHWGLLGQAEKTQGQGTANQL---QPENGVSPGG----TDNHASVNASPKTALTGP--TE 2003 GH GL+G QG P+ P G T + L GP + Sbjct: 1483 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPK 1542 Query: 2004 GAVLLEKCKGSRAAMSLQEEA--EPTPSPPSPNRESL-ALALTAAHSR 2048 GA KGS + EA P PP P E + L + A+ +R Sbjct: 1543 GA------KGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTR 1584 Score = 55.1 bits (131), Expect = 1e-06 Identities = 133/519 (25%), Positives = 159/519 (30%), Gaps = 89/519 (17%) Query: 3415 GGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSE 3474 G P RG PG PG L K PG A PG+D PP P + Sbjct: 1006 GETGPMGERG--HPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFP--GD 1061 Query: 3475 GSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAAL 3534 LP + + +G P P G P P P P PA Sbjct: 1062 RGLPGPV---GALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGE 1118 Query: 3535 ADGRGDCALDGALERPENEASPGSPGPLLQQALPLG--------ASLPRPGARG------ 3580 G+ G R + G PGP A P+G + PG +G Sbjct: 1119 KGAPGEKGPQGPAGRDGLQGPVGLPGP----AGPVGPPGEDGDKGEIGEPGQKGSKGDKG 1174 Query: 3581 -QDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHK 3639 Q G P G+ GA G P Q+ QK E GP G Sbjct: 1175 EQGPPGPTGPQGPIGQPGPSGADGEPGP-RGQQGLFGQKGDEGPRGFP----GPPGPVGL 1229 Query: 3640 GSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPG-ELARGTENGM-KPAT-- 3695 P G + + D P P PR G APG + +G G+ P Sbjct: 1230 QGLPGPPGEKGETGDVGQMGPPG-----PPGPRGPSG--APGADGPQGPPGGIGNPGAVG 1282 Query: 3696 PKAKPG----PSSQGSGSPRPGTK-----------TGGGSQPQPASGQLQSETATTPAKP 3740 K +PG P G G P PG K +G P P +P Sbjct: 1283 EKGEPGEAGEPGLPGEGGP-PGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV 1341 Query: 3741 SFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK-EKGESSTKRKKGQVPGPA- 3798 FP P P P A + GE G GS GP E G S K+G PGPA Sbjct: 1342 GFPG-DPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP-PGPAG 1399 Query: 3799 ---RSESVGSFGRA----------PSAPDKPPRTPRK---QATPSRV----LPTKPKPNS 3838 R G+ G A P P P P + P V LP P P+ Sbjct: 1400 PEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDG 1459 Query: 3839 QNKPRPPP-------SEQRKAEPGHTQRKDRLGKAFPQG 3870 P PP K E GH +G QG Sbjct: 1460 PPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQG 1498 Score = 52.4 bits (124), Expect = 9e-06 Identities = 106/420 (25%), Positives = 139/420 (33%), Gaps = 77/420 (18%) Query: 3425 VRRPGAPGQKARALEGTLPSK---RRRVAMPGSAPGPGEDRPPPRGSSPILSEGS----- 3476 + PG G K E P + + PG + GE P PRG + + Sbjct: 1161 IGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGE--PGPRGQQGLFGQKGDEGPR 1218 Query: 3477 ----LPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPA 3532 P + L P KG + + P RG PS P P Sbjct: 1219 GFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRG---PSGAPGADGPQGPPGGI 1275 Query: 3533 ALADGRGDCALDGALERPENEASPGSPGPLLQ-----QALPLGASLPRPGARGQDAE--- 3584 G+ G P G PGP + ++ P GA+ P PG +G + Sbjct: 1276 GNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGP-PGPKGPPGDDGP 1334 Query: 3585 -GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEK-EVSSSHMVSEGGPRGTFHKGSA 3642 G P+ F G PG G D D E + S E GP G K Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP 1394 Query: 3643 TKPAGCQSSSKDRSAAST------PSKALKFPVHPRKAVGSLAPGELARGT-----ENGM 3691 PAG + ++ A P K P+ P+ A G P L RG E G+ Sbjct: 1395 PGPAGPEGRQGEKGAKGEAGLEGPPGKT--GPIGPQGAPGKPGPDGL-RGIPGPVGEQGL 1451 Query: 3692 K-------PATPKAKPG-PSSQGSGSPR--------------PGTKTGGGSQ----PQPA 3725 P P PG P +G P+ PG + G + PQ + Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1511 Query: 3726 SGQLQSETATTPAKPSFPSRSPAPERLPA-----RAQAKSCTKGPR-EAGEQGPHGSLGP 3779 SG + T P+ P P P P LP A+ S GP+ EAG GP G GP Sbjct: 1512 SGPKGEQGITGPSGPIGP---PGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP 1568 Score = 47.4 bits (111), Expect = 3e-04 Identities = 122/540 (22%), Positives = 165/540 (30%), Gaps = 83/540 (15%) Query: 905 TPDPQTPRPGDRGCPARGRPKT-----------RSLGLAPTEADAPSQGRQQRRGKQLKL 953 TP Q P P + G +T LG PT + P + ++ +L Sbjct: 251 TPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETTEVPEEL 310 Query: 954 FRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVP 1013 ++ E S G G+ + P P T G P P Sbjct: 311 TPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDP 370 Query: 1014 RAAA-LPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEE 1072 A A +P T + P G + +E I L E + + Sbjct: 371 GAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETI-------RNLDENYYDPYYDP 423 Query: 1073 DEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGG 1132 P GPG + E GPR ++ QK A + P PE P G Sbjct: 424 TSSPSEIGPGMPANQDT-----IYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAG 478 Query: 1133 SRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLD 1192 PGP P GP+ + G G P RP + D L P T R Sbjct: 479 -LPGP---PGTMGPTG--QVGDPGERGPP---GRPGLPGADGLPGPPGTMLMLPFRFGGG 529 Query: 1193 FPQEAKEP-ETAEESAPDS--TEFTEALRSPPAACAGEMGAS--PGLLIPEQPPPSRHDT 1247 +K P +A+ES + + ALR P AG MG + PG + P + + Sbjct: 530 GDAGSKGPMVSAQESQAQAILQQARLALRGP----AGPMGLTGRPGPVGPPGSGGLKGEP 585 Query: 1248 GTPKPSGSLANTAPHGSSPTPGVGSLLGGPG-----GTQAPVSHNSKDPPARQPGEFLAP 1302 G P G P G + PG G G G P D A PGE Sbjct: 586 GDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGE-KGH 644 Query: 1303 VANPSSTACPKPSVLSSKISSFG-CDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKD 1361 +P + P P + G P G +P GP+ Sbjct: 645 RGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP----------------------GPRG 682 Query: 1362 LAGCFLEELHPKPSARDAPPASSSCLCQDGEDA--GSLEPQLPRSPPGTAETEPGRAASP 1419 L G P PP DG+ G++ PQ PPG + PG P Sbjct: 683 LLG---------PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPG-QQGNPGAQGLP 732 Score = 43.9 bits (102), Expect = 0.003 Identities = 256/1093 (23%), Positives = 327/1093 (29%), Gaps = 262/1093 (23%) Query: 2072 GDSPAPSVGDLAAC----------APSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQ 2121 G P PS + A P+PT AA MP + +E+ + G+G Sbjct: 287 GKEPTPSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDV--------GIGDY 338 Query: 2122 LPASPSCRDPPGPQQLLACSPAWA----PLEEADGVQ---ATTDTGAEDSPVAPPSLTTS 2174 P P L P + G + +T DT +P PP Sbjct: 339 DYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGAD 398 Query: 2175 PCDPK--EALAGCLLQGEGSPLEDPSSWP-------PGSVSAVTCTHSGDTPKDSTLRIP 2225 + + E L + P DP+S P P + + G + P Sbjct: 399 DLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEP 458 Query: 2226 EDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGR-GLPGPDPQSRG 2284 L E P P AG P + TG P G+ GR GLPG D Sbjct: 459 AIIEPGMLIEGPPGPEGP--AGLPGPPGTMGPTGQVGDP-GERGPPGRPGLPGAD--GLP 513 Query: 2285 APPHTN---PDRMPRGHSSYSPSNTARLGHREGQAVTAV-------PTEPPTLQG----A 2330 PP T P R G + S + QA+ P P L G Sbjct: 514 GPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPV 573 Query: 2331 GPDSPACLEGEMGTSSKE--------PEDPGTP----ETGRSGATKMPRVTCPSTGLGLG 2378 GP L+GE G + P G P G GA MP T P G Sbjct: 574 GPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGF- 632 Query: 2379 RTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS-------RGYKKKPASTE 2431 D + P + P G P P D +R RG +P Sbjct: 633 ----------DGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGP-- 680 Query: 2432 NGQWKGQAPHGPVTCEVCAASFRSGP----GLSRHKARKHRPHP-GAPAEPSPAALPAQQ 2486 G + P GP GP G+ K P G P P P Q Sbjct: 681 RGLLGPKGPPGP-----------PGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQ 729 Query: 2487 PLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHV-TQPPPAQGSKEVLRAPGSPHSQQL 2545 L PP G++ P G P PP KE PG Q Sbjct: 730 GLPGPQGAIGPP--------GEKGPLGKPGLPGMPGADGPPGHPGKE--GPPGEKGGQG- 778 Query: 2546 HPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRR-EPTVDSPSHSEGKSN 2604 PP P + P P P K A+ G + + E D +G Sbjct: 779 -PPGP-------QGPIGYPGPRGV-------KGADGIRGLKGTKGEKGEDGFPGFKGDMG 823 Query: 2605 KK--RGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGE 2662 K RG++ R E GRG L V G P G Sbjct: 824 IKGDRGEIGPPGPRGED-----GPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGR 878 Query: 2663 QPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGA 2722 Q P+ + PG GA GE G + PG PG P GQ+G Sbjct: 879 QGPKGSIGFPG-FPGAN---------GEKGGRGTPGK----PG----------PRGQRGP 914 Query: 2723 SA-RGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSP 2781 + RG GPR G+ + G P +S G N P GP GFP P Sbjct: 915 TGPRGERGPR-----GITGKPG--PKGNSGGDGPAGPPGERGPNGPQ-GPTGFPGPKGPP 966 Query: 2782 ADSTTSSCLQGLPDNPDTQG--------------GVQGPEGPTPDASGSSAKDPPSLFDD 2827 GLP +P +G GV GP+GPT + + P Sbjct: 967 GPPGKD----GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG---- 1018 Query: 2828 EVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARLPTDLSDS 2887 P G + P + GK K GDP GPA L Sbjct: 1019 ---------PPGPPGEQGLPGLAGKEGTK--------------GDP--GPAGL------- 1046 Query: 2888 SSLCLCHEDPWEDEDPA--GLPESFLLDGFL-------NSRVPGIDPWAPGLSLWALEPS 2938 P +D P G P L G + N PG P P S P+ Sbjct: 1047 ---------PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPG--PPGPAGSPGERGPA 1095 Query: 2939 REAGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPE----PPS 2994 AG +P P P P +G + PA D +G P PP Sbjct: 1096 GAAGPIGIPGR-PGPQGPPG-PAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPG 1153 Query: 2995 LERERCDGGLPGNTHLLPLRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFE-GT 3053 + ++ + G PG K E GP + P+G PGPS D E G Sbjct: 1154 EDGDKGEIGEPGQK----------GSKGDKGEQGPPGPTGP-QGPIGQPGPSGADGEPGP 1202 Query: 3054 ASSQGPQSRRTEE 3066 QG ++ +E Sbjct: 1203 RGQQGLFGQKGDE 1215 Score = 40.8 bits (94), Expect = 0.027 Identities = 72/296 (24%), Positives = 97/296 (32%), Gaps = 78/296 (26%) Query: 3631 GGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-------GEL 3683 GGPRG KG +PA + P ++ P P G P G++ Sbjct: 446 GGPRG--EKGQKGEPAIIE-----------PGMLIEGPPGPEGPAGLPGPPGTMGPTGQV 492 Query: 3684 ARGTENGMKPATPKAKPG-PSSQGSGSPRPGT------KTGGGSQ-----PQPASGQLQS 3731 E G P +PG P + G P PGT + GGG P ++ + Q+ Sbjct: 493 GDPGERG-----PPGRPGLPGADGLPGP-PGTMLMLPFRFGGGGDAGSKGPMVSAQESQA 546 Query: 3732 ETATT--------PAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKG 3783 + PA P + P P P K P + G QGP G GP Sbjct: 547 QAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG---EPGDVGPQGPRGVQGPPGPA 603 Query: 3784 ESSTKRKKGQVPG----PARSESVGSFG----------------RAPSAPDKPPRTPRKQ 3823 +R + G P ++ G G PS P PP ++ Sbjct: 604 GKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGER 663 Query: 3824 ATPSRV----LPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDR---LGKAFPQGRP 3872 V LP +P P P+ PP PG T + G PQG P Sbjct: 664 GDDGEVGPRGLPGEPGPRGLLGPKGPPGP--PGPPGVTGMDGQPGPKGNVGPQGEP 717 Score = 38.5 bits (88), Expect = 0.13 Identities = 32/99 (32%), Positives = 37/99 (37%), Gaps = 10/99 (10%) Query: 3206 PAPKHHRGKRSAGK---AAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDS 3262 P PK RG++ AAG PG + K SPG P P P G A D Sbjct: 1302 PGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEP-GPAGQDG 1360 Query: 3263 ASATALADAGSPGPPRTTPSPSP--DPWAGGEPLLQATP 3299 D G G P T SP P +P G P + P Sbjct: 1361 PP----GDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPP 1395 Score = 37.7 bits (86), Expect = 0.23 Identities = 41/138 (29%), Positives = 48/138 (34%), Gaps = 22/138 (15%) Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPW--GQEGE-AKKDSPGERA 3243 P G G +A L P K HRG G PGD G +GE + PGE Sbjct: 626 PKGDRGFDGLAGL------PGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPG 679 Query: 3244 KPRARSTPSNPDGAATPDSASATALADAGSPGP-----PRTTPSPSPDPWAGGEPLLQAT 3298 PR P P G P + G PGP P+ P P P G P Q Sbjct: 680 -PRGLLGPKGPPGPPGPPGVTGM----DGQPGPKGNVGPQGEPGP---PGQQGNPGAQGL 731 Query: 3299 PVHEACKDPSRDCHHCGK 3316 P + P + GK Sbjct: 732 PGPQGAIGPPGEKGPLGK 749 Score = 35.8 bits (81), Expect = 0.86 Identities = 33/120 (27%), Positives = 42/120 (35%), Gaps = 14/120 (11%) Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKP- 3245 P G +G + + P P+ G A G PG +K PGE +P Sbjct: 1235 PPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG 1294 Query: 3246 -RARSTPSNPDGAATPDSASATALADAGSPGP--------PRTTPSP---SPDPWAGGEP 3293 P P G S + A AG PGP P+ +P P DP GEP Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSGA-AGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEP 1353 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 89.4 bits (220), Expect = 7e-17 Identities = 365/1807 (20%), Positives = 563/1807 (31%), Gaps = 240/1807 (13%) Query: 1168 SVAPKDPLQVPTNTETSEETR-PSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAG 1226 SV +P P ++ ++E T P E T S+P S + T + S ++ Sbjct: 1657 SVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS--- 1713 Query: 1227 EMGASPGLLIPEQPPPSRHDTGTP----KPSGSLANTAPHGSSPTPGVGSLLGGPGGTQA 1282 G S P S H T P P S +TA H S PG PG T A Sbjct: 1714 --GVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSS---PGSTDTTLSPGSTTA 1768 Query: 1283 PVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAK 1342 PG + ++TA + SS G + P G + Sbjct: 1769 SSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS--PAGSTTRQ 1826 Query: 1343 KGPQPYSS-PHS-ELFLGPKDLAGCFLE---ELHPKPSARDAP--PASSSCLCQDGEDAG 1395 + S P S + P F+E H PS+ ASS+ L + E Sbjct: 1827 GESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEEST- 1885 Query: 1396 SLEPQLPRSPPGTAET-EPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF 1454 + SP TA T P R+ + +E S+ + P S +A+ S Sbjct: 1886 ----TVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 1941 Query: 1455 ACADPPQKTVPSDPPYPSFLLLEEVS------PMLPSHFPDLSGGKVLSKTCPPERTVVP 1508 T+ S P S L+ E S +HFPD S S+ + Sbjct: 1942 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD 2001 Query: 1509 GAAPSLPGKGSGCSVAL----MSHLSEDELEIQKLV--TELESQLQRSKDTRGAPRELAE 1562 + S SV L S +S +E L T ++S +PR A Sbjct: 2002 ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPAT 2061 Query: 1563 AES-VGRVELGTGTEPPSQ--RRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATV 1619 S G E + R T D+ + L+R ST S T+ Sbjct: 2062 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSR--HSTTSHSSPGSTDTTL 2119 Query: 1620 EAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGL 1679 G + H + + F FH P G++ T L Sbjct: 2120 LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSP----GSTHTTL 2175 Query: 1680 CQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPD---QELSFPKNKEAASSQESEDS 1736 S + S P+ + SP + +F + + + S S Sbjct: 2176 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 2235 Query: 1737 LRLLPCEQRGGFLPEPGTADQPHRGAPAP---EAFGSPAVHLAPDLAFQGDGAPPLDATW 1793 P E+ + PG+ H A + + S H +PD + Sbjct: 2236 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS------------- 2282 Query: 1794 PFGASPSHAAQGHSAGRAGGHLHPTAGRPG------FEGNEFAP----AGASSLTAPRGR 1843 G +PS A HS G + PG G+ P A + ++PR Sbjct: 2283 --GTTPSSA---HSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSP 2337 Query: 1844 EAWLVPVPSPAC-VSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGIL----GLQELT 1898 L P + V + RSQ + + PG+++ + G E T Sbjct: 2338 TTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETT 2397 Query: 1899 PAAQSPPRVNPSGLEGGTVEGGKVACGPA----QGSPGGV--QVTTLP-AVAGHQLGLEA 1951 ++P + G E T + + G+ + T P + A Q GL A Sbjct: 2398 VFPRTPT-TSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 2456 Query: 1952 DGHWGLLGQAEKT---QGQGTANQLQPENGVSPG----GTDNHASVNASPKTALTGPTEG 2004 LG+ T T L P + G T + S +++ T L G Sbjct: 2457 TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT 2516 Query: 2005 AVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRT--PERASSP 2062 L EK S + + T SP + ++ + +HS+ GS T P+ ++P Sbjct: 2517 PSLSEK---STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTP 2573 Query: 2063 GLNKPLLATGDSPAPSVGDLAACA----------------PSPTSAAHMPCSLGPLPRED 2106 GL++ + SP + L + P T A P S L Sbjct: 2574 GLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQ 2633 Query: 2107 PLTSPSRAQGGL-----------GGQLPASPSCRDPPG-PQQLLACSPAWAPLEEADGVQ 2154 T+ + G G + AS G P+ L+ + + +P + + Sbjct: 2634 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTT 2693 Query: 2155 ATTDTGAEDSPVAPPSLTTSPCDPKEAL-------------AGCLLQGEGSPLEDPSSWP 2201 T + + +PPS T+P + A G S P Sbjct: 2694 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP 2753 Query: 2202 PGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV--------SPSV 2253 S + + HS + + + ++ PG T+P L+ A SP+ Sbjct: 2754 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 2813 Query: 2254 AVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYS--PSNTARLGH 2311 + ++S G+E+ R PG + T P + YS P +T Sbjct: 2814 TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVF 2873 Query: 2312 REGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPED----PGTPETGRSGATKM-- 2365 + EP T + L E T+S E+ PG+P + ++G Sbjct: 2874 PRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLT 2933 Query: 2366 ------PRVTCPSTGLGLGRTTAPS-STASDFQSDSPQSHRNASHQ---TPQGDPLGPQD 2415 T PS+ G T +P+ ST S +S S + S T G P P Sbjct: 2934 TADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS- 2992 Query: 2416 LKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGP-------------GLSRH 2462 L ++S + P S + V+ E + + G GLS+ Sbjct: 2993 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE 3052 Query: 2463 KARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRV-------SG---KERPN 2512 H A SP + A + P + SG P Sbjct: 3053 PTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 3112 Query: 2513 HSRGDPSHVTQPPPAQGS----KEVLRAPGSPHSQQL--HPPSPTEHEVDVKT-----PA 2561 HS H T P + S +E P S PP T V+V T P+ Sbjct: 3113 HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPS 3172 Query: 2562 SKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESIL 2621 S P H + GR TV S + G + + E + Sbjct: 3173 STPTT--------HFSASSTTLGRS-EESTTVHSSPGATGTALFPTRSATSVLVGEPTTS 3223 Query: 2622 PVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAET 2681 P+S S + P + A + P + +T GV E + + Sbjct: 3224 PIS----SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 3279 Query: 2682 DQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQP-----TGQKGASARGFWGPRETKAL 2736 G T PG + + A P T G++ GP T Sbjct: 3280 HSRP---GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTF- 3335 Query: 2737 GVCKESGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTT----SSCLQG 2792 SG E + + + G+ E +TP G P T+ SPA STT S+ Q Sbjct: 3336 ----HSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS 3391 Query: 2793 LPDNPDT 2799 P++ DT Sbjct: 3392 WPNSKDT 3398 Score = 88.2 bits (217), Expect = 1e-16 Identities = 288/1376 (20%), Positives = 442/1376 (32%), Gaps = 219/1376 (15%) Query: 1658 SPRGANFHFQPVQKAGASKTGLCQAEGDSR----PPQDVCLPEPSKQPGPQLD--AGSLA 1711 SPR + P A + +G+ + S P + P+ + PG + A Sbjct: 286 SPRSPDRTLSP---ARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSI 342 Query: 1712 KCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPE-PGTADQPHRGAPAPEAFGS 1770 S D LS P +S + P + LP+ T+ P + GS Sbjct: 343 PGSTDTTLS-PGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGS 401 Query: 1771 PAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFA 1830 P L+P + +G P +WP S A G ++ F Sbjct: 402 PHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSA-------------------FV 442 Query: 1831 PAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDG 1890 + ++P P + S T P S P+ P P + + Sbjct: 443 KLSTTYHSSPSS-----TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGH 497 Query: 1891 ILGLQELTPAAQSPPRVNPSGL-EGGTVEGGKVACGPAQGSPGGVQVTTLPAVAG----- 1944 + +E T +SP E T G GS + +T A Sbjct: 498 V---EESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTS 554 Query: 1945 --HQLGLEADGHW----GLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPK--- 1995 LG H+ + G++E+++ ++ + G T + +++P Sbjct: 555 YHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPIS 614 Query: 1996 ------TALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRS 2049 TAL G T L EK S S + T P S ++ T +HSR Sbjct: 615 SGSMETTALPGSTTKPGLSEK---STTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRP 671 Query: 2050 GSEGRT--PERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGP------ 2101 GS T P + PGL++ A+ SP P+ L +P T+A+ SLGP Sbjct: 672 GSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTL---SPGSTTAS----SLGPEYTTFH 724 Query: 2102 ----LPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATT 2157 L + A G L +P S R P SPA + + + + Sbjct: 725 SRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPH-----TTLSPAGSTTRQGESTTFHS 779 Query: 2158 DTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPS------SWPPGSVSAVTCT 2211 ++D+ APP+ T++ +P GSP P+ S G V T Sbjct: 780 WPSSKDTRPAPPTTTSAFVEPSTT-------SHGSPSSIPTTHISARSTTSGLVEESTTY 832 Query: 2212 HSGDTPKDSTLRIPE-DSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQ 2270 HS T+ PE D+ + ES +S + +PS + L PT + Sbjct: 833 HS-SPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST---TSALVEEPTSYHSS 888 Query: 2271 AGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGA 2330 G P S + + HSS + T L R +V L G Sbjct: 889 PGSTATTHFPDS--STTSGRSEESTASHSSQDATGTIVLPARSTTSV---------LLGE 937 Query: 2331 GPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDF 2390 SP G M T++ P TP T P+T L TT SS S+ Sbjct: 938 STTSPIS-SGSMETTAL-PGSTTTPGLSERSTTFHSSPRSPATTLSPASTT--SSGVSE- 992 Query: 2391 QSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCA 2450 +S + +S ++H T D L + S P ST+ T + A Sbjct: 993 ESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD-------------TTLLPA 1039 Query: 2451 ASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKER 2510 ++ SGP S+ H SP + A ++S Sbjct: 1040 STTTSGP--SQESTTSHSSSGSTDTALSPGSTTALS-----------FGQESTTFHSNPG 1086 Query: 2511 PNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAR 2570 H+ P T + S V + GSP + L P S T + ++ A + P Sbjct: 1087 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRT-TLSPASSTSPGLQGESTAFQTHPASTH 1145 Query: 2571 EDELHPKQAEK--REGRRWRRE----PTVDSPSHSEGKSNKKRGKLRGRRLREESILPVS 2624 P A E + R PT P+ S + ++ + P S Sbjct: 1146 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 1205 Query: 2625 ADVISDGRG----SRPSPAMASYAASPSHCLSVEGGPEADGE--QPPR--LATLGPGVME 2676 A + GRG SR SP P + G EA PR TL P M Sbjct: 1206 AHSTTSGRGESTTSRISPGSTEITTLPG-STTTPGLSEASTTFYSSPRSPTTTLSPASMT 1264 Query: 2677 GAAETDQEALCAGETG---------AQKPPG----------------DRMLCPGRMDGAA 2711 ++ + G + PG + + P + Sbjct: 1265 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSV 1324 Query: 2712 LGEQPT--GQKGASARGFWGPRETKALGVCKES----GSEPAEDSSRAHSRSEEGVWEEN 2765 GE+PT + AS ++ G+ +ES GS + + + + + EE+ Sbjct: 1325 HGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES 1384 Query: 2766 TPPLGPLGFPETSSSPADSTTSSCL-QGLPD--NPDTQGGVQGPEGPT------------ 2810 T G T SPA STTS + + P +P + P PT Sbjct: 1385 TTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY 1444 Query: 2811 -----PDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQP 2865 PDA+ S A S +E S S P T + ++P T Sbjct: 1445 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPT----TSH 1500 Query: 2866 SFEEGGDPTLGPARLPTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVP 2921 S + + TL P S H P + E LP+ + G + + P Sbjct: 1501 SSQGSTEATLSPGSTTASSLGQQSTTF-HSSPGDTETTL-LPDDTITSGLVEASTP 1554 Score = 85.1 bits (209), Expect = 1e-15 Identities = 383/1828 (20%), Positives = 571/1828 (31%), Gaps = 270/1828 (14%) Query: 1135 PGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFP 1194 P SP +G S + +T A+ P P P++ T S + P+ FP Sbjct: 2679 PASSTSPGLQGESTTFQTHPASTHTTPS----PPSTATAPVEESTTYHRSPGSTPTTHFP 2734 Query: 1195 QEA-----KEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGT 1249 + E T S+PD++ T + S + +G ++ + P + T Sbjct: 2735 ASSTTSGHSEKSTIFHSSPDASGTTPS--SAHSTTSGRGESTTSRISPGSTEITTLPGST 2792 Query: 1250 PKPSGSLANTAPHGSSPTP------------GVG----SLLGGPGGTQAPVSHNSKDPPA 1293 P S A+T + S +P GVG + PG T + VS S P Sbjct: 2793 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 2852 Query: 1294 RQPGEFLAPVANPSSTACP------KPSVLSSKISSFGCDPAG-----FNRDPLGVPVAK 1342 ++P ST SV + ++F PA F D + + Sbjct: 2853 LSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 2912 Query: 1343 KGPQPYSSPHSELFLGPKDLAGCFL-EELHPKPSARDAP-----PASSSCLCQDGEDAGS 1396 + SP S P L L EE PS+ + PA S+ GE S Sbjct: 2913 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPS 2972 Query: 1397 LEPQLPRSPPGTAETE--PGRAASPPTLESSSLF---PDLPVDRFDPPLYGSLSANRDSG 1451 R P + ET PG +P E S+ F P P P S + +S Sbjct: 2973 ------RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 3026 Query: 1452 LPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD--LSGGKVLSK----------- 1498 + T D S L E + + LS G + Sbjct: 3027 TSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHS 3086 Query: 1499 -------TCPPERTVVPGAAP-SLPGKGSGCSV-ALMSHLSEDELEIQKLVTELESQLQR 1549 T P+ T+ G S P S S+ ++ S +Q+ T +S Sbjct: 3087 SPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS 3146 Query: 1550 SKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTA-H 1608 S T P A V + P+ + +T L R EST H Sbjct: 3147 SDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTT----------LGRSEESTTVH 3196 Query: 1609 REGAESAVA---TVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFH 1665 + A T A G P S LP + + A S + F+ Sbjct: 3197 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS----TTTAGLSEKSTTFY 3252 Query: 1666 FQP------VQKAGASKTGLCQAE--GDSRP--PQDVCLPEPSKQPGPQLD--AGSLAKC 1713 P + A + +G+ + SRP P + PG + A + Sbjct: 3253 SSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPG 3312 Query: 1714 SPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQP-HRGAPAPEAFGSPA 1772 S D LS P + A+S + P LP+ TA P + GSP Sbjct: 3313 STDTTLS-PGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPH 3371 Query: 1773 VHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTA-GRPGFEGNEFAP 1831 L+P + G +WP + A ++ A L T+ G P Sbjct: 3372 TTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS--AFVELSTTSHGSPS--STPTTH 3427 Query: 1832 AGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVA------ 1885 ASS T R E+ V A + P+R + + PG Sbjct: 3428 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 3487 Query: 1886 -----KSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLP 1940 + ++ T S P + +E T SPG T P Sbjct: 3488 DTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT---------SYHSSPGSTATTHFP 3538 Query: 1941 AVAGHQLGLEADGHWGLLGQAEKT---QGQGTANQLQPENGVSPGGTDNHASVNASPKTA 1997 + E A T + T + L E+ SP S + TA Sbjct: 3539 DSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP------ISSGSMETTA 3592 Query: 1998 LTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRT-- 2055 L G T L EK S S T SP S ++ T +HSR GS T Sbjct: 3593 LPGSTTTPGLSEK---STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 3649 Query: 2056 PERASSPGLNKPLLATGDSPAPSVGDLAACAPSP----------------TSAAHMPCSL 2099 P+ ++PGL++ + SP + L + + T A P S Sbjct: 3650 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGST 3709 Query: 2100 GPLPREDPLTSPSRAQGGL-----------GGQLPASPSCRDPPG-PQQLLACSPAWAPL 2147 L T+ + G G + AS G P+ L+ + + +P Sbjct: 3710 TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 3769 Query: 2148 EEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEAL-------------AGCLLQGEGSPL 2194 + + T + + +PPS T+P + A G Sbjct: 3770 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 3829 Query: 2195 EDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV----- 2249 S P S + + HS + + + ++ PG T+P L+ A Sbjct: 3830 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 3889 Query: 2250 ---SPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSY--SPS 2304 SP+ + ++S G+E+ R PG + T P + Y SP Sbjct: 3890 SPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPG 3949 Query: 2305 NTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPED----PGTPETGRS 2360 +T + EP T + L E T+S E+ PG+P + ++ Sbjct: 3950 STETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT 4009 Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420 G T + LG TT PSS+ S SP + T G L S Sbjct: 4010 GLP----ATLTTADLGEESTTFPSSSGSTGTKLSP------ARSTTSG-------LVGES 4052 Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480 + P+STE P P T P LS + A SPA Sbjct: 4053 TPSRLSPSSTET----TTLPGSPTT-----------PSLSEKSTTFYTSPRSPDATLSPA 4097 Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSP 2540 + E + P +H + + S G T +QGS E +PGS Sbjct: 4098 TTTSSGVSEESSTSHSQP-GSTHTTAFPDSTTTS-GLSQEPTTSHSSQGSTEATLSPGST 4155 Query: 2541 HSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSE 2600 + L S T H T + PD L + S S Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTL-LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214 Query: 2601 GKSNKKRGKLRGRRLREESILPVSADV----ISDGRGSRPSPAMASYAASPSHCL----- 2651 G + + + P S +S SRPS ++ ++ S L Sbjct: 4215 GLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 4274 Query: 2652 --SVEGGPEADGEQ--PPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRM 2707 +V P A G P R AT V+ G T + + ET A PG Sbjct: 4275 STTVHSSPGATGTALFPTRSAT---SVLVGEPTTSPISSGSTETTA---------LPGST 4322 Query: 2708 DGAALGEQPTG--QKGASARGFWGPRETKALGVCKESGSEPAEDSSR-----AHSRSEEG 2760 A L E+ T S P T + GV +ES + + S S + G Sbjct: 4323 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPG 4382 Query: 2761 VWEENTPPLGPLGFPETSSSPADSTTSS 2788 V +E+T G +T+ SP +T SS Sbjct: 4383 VSQESTASHSSPGSTDTTLSPGSTTASS 4410 Score = 79.3 bits (194), Expect = 7e-14 Identities = 218/1007 (21%), Positives = 316/1007 (31%), Gaps = 172/1007 (17%) Query: 1984 TDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALT 2043 T + S ++ TAL G T A L EK S S + T SP S ++ T Sbjct: 1664 TTSPISSGSTETTALPGSTTTAGLSEK---STTFYSSPRSPDTTLSPASTTSSGVSEEST 1720 Query: 2044 AAHSRSGSEGRT--PERASSPGLNKPLLATGDSP-------APSVGDLAACAPSPTSAAH 2094 +HSR GS T P + PG+++ A+ SP +P ++ P T+ Sbjct: 1721 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 1780 Query: 2095 MPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQ 2154 P S D T A G L P S P SPA + + + Sbjct: 1781 SPGSTETTLLPDNTT----ASGLLEASTPVHSSTGSPH-----TTLSPAGSTTRQGESTT 1831 Query: 2155 ATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSG 2214 + ++D+ APP+ T++ + G PSS P SA + T G Sbjct: 1832 FQSWPSSKDTMPAPPTTTSAFVELSTTSHG-----------SPSSTPTTHFSASSTT-LG 1879 Query: 2215 DTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRG 2274 + + +T+ S P+A A +PS A T G Sbjct: 1880 RSEESTTVH------------------SSPVATATTPSPARSTTS--------------G 1907 Query: 2275 LPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDS 2334 L +P T P ++ S +R H + T + PP+ A + Sbjct: 1908 LVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSH---SSTTHTISSPPSTTSALVEE 1964 Query: 2335 PACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDS 2394 P G+++ + +GRS + + +TG + + +S + S Sbjct: 1965 PTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 2024 Query: 2395 PQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFR 2454 P S + G P L ++S + P S V+ E + R Sbjct: 2025 PISSGSMETTALPGSTTTP-GLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSR 2083 Query: 2455 SG-------------PGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKK 2501 G PGLSRH H PA+ P + P Sbjct: 2084 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2143 Query: 2502 SHRVS---------GKERPN-HSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQ------QL 2545 +S G+E HS +H T P + S ++ A HS L Sbjct: 2144 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2203 Query: 2546 HPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEK--REGRRWRRE----PTVDSPSHS 2599 P S T + ++ A + P P A E + R PT P+ S Sbjct: 2204 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 2263 Query: 2600 EGKSNKKRGKLRGRRLREESILPVSADVISDGRG----SRPSPAMASYAASPSHCLSVEG 2655 + ++ + P SA + GRG SR SP P Sbjct: 2264 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG------- 2316 Query: 2656 GPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG-DRMLCPGRMDGAALGE 2714 +T PG+ E A T P L P M +GE Sbjct: 2317 ------------STTTPGLSE-----------ASTTFYSSPRSPTTTLSPASMTSLGVGE 2353 Query: 2715 QPTGQKG--ASARGFWGPRETKALGVCKES--------GSEPAEDSSRAHSRSEEGVWEE 2764 + T + S P T G+ +ES GS R + S G EE Sbjct: 2354 ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRG--EE 2411 Query: 2765 NTPPLGPLGFPETSSSPADSTTSSCLQ---GLPDNP-DTQGGVQGPEGPTPDASGSSAKD 2820 T T+ DSTTS + P +P TQ G+ T D S Sbjct: 2412 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL-TTADLGEESTTF 2470 Query: 2821 PPSLFDDEVSFSQLFPPGGRLTRKRNP-HVYGKRCEKPVLP-LPTQPSFEE--------- 2869 P S + S L + P + E LP PT PS E Sbjct: 2471 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 2530 Query: 2870 -GGDPTLGPARLPTD-LSDSSSLCLCHEDPWEDEDPAGLPESFLLDG 2914 D TL PA + +S+ SS H P A P+S G Sbjct: 2531 RSPDATLSPATTTSSGVSEESS--TSHSQPGSTHTTA-FPDSTTTPG 2574 Score = 76.6 bits (187), Expect = 4e-13 Identities = 380/1828 (20%), Positives = 569/1828 (31%), Gaps = 342/1828 (18%) Query: 1124 PANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTET 1183 P + PG S R P+ +L + G ++ + + P T Sbjct: 2037 PGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSG---VSEESTTSHSRPGSTHTTAFP 2093 Query: 1184 SEETRPSLDFPQEAKEPETAEESAPDSTEFT----EALRSPPAACAGEMGASPGLLIPEQ 1239 T P L T S+P ST+ T S P+ + +SPG Sbjct: 2094 DSTTTPGLS------RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 2147 Query: 1240 PPPS-------RHDTGTPKPSGSLANTAPHGSSPTPG-------VGSLLGGPGGTQAPVS 1285 P S + T GS T S+ + G V S G P T +P S Sbjct: 2148 SPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS 2207 Query: 1286 HNSKDPPARQPGEFLAPVANPSSTACPK--PSVLSSKISSFGCDPAGFNRDPLGVPVAKK 1343 S P Q GE A +P+ST PS ++ + + ++R P P Sbjct: 2208 STS---PGLQ-GESTAFQTHPASTHTTPSPPSTATAPVE----ESTTYHRSPGSTPTTHF 2259 Query: 1344 GPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPR 1403 +S HSE H P A P+S+ +G E R Sbjct: 2260 PASSTTSGHSEKST-----------IFHSSPDASGTTPSSAH-----STTSGRGESTTSR 2303 Query: 1404 SPPGTAE--TEPGRAASPPTLESSSLF---PDLPVDRFDPPLYGSLSANRDSGLPFACAD 1458 PG+ E T PG +P E+S+ F P P P SL +S + Sbjct: 2304 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2363 Query: 1459 PPQKTV-PSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPS---- 1513 TV P+ P L E S + S P + V +T T V G P+ Sbjct: 2364 STHSTVSPASTTTPG---LSEESTTVYSSSPGSTETTVFPRT---PTTSVRGEEPTTFHS 2417 Query: 1514 -------------------------LPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQ 1548 PG + L + L+ +L E + Sbjct: 2418 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG------EESTTFP 2471 Query: 1549 RSKDTRGAPRELAEAESVGRVELGTGTE-PPSQRRTCQATVPHEDTFSAADLTRVGESTA 1607 S + G A + + G V T + PS T T+P T + +ST Sbjct: 2472 SSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTET--TTLPGSPTTPSLS----EKSTT 2525 Query: 1608 HREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQ 1667 S AT+ G ++ H + A D + S H Sbjct: 2526 FYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSS 2585 Query: 1668 PVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEA 1727 P G++ T L A + P S PG A S + LSF + Sbjct: 2586 P----GSTDTTLLPASTTTSGPSQESTTSHSS-PGSTDTALSPGSTTA---LSFGQESTT 2637 Query: 1728 ASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDG-- 1785 S L P + E T + H +P SPA +P L QG+ Sbjct: 2638 FHSSPGSTHTTLFPDSTTSSGIVEAST--RVHSSTGSPRTTLSPASSTSPGL--QGESTT 2693 Query: 1786 ------------APPLDATWPF----------GASP------SHAAQGHSAGRAGGHLHP 1817 +PP AT P G++P S GHS H P Sbjct: 2694 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP 2753 Query: 1818 TAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQL 1877 A P+ A S T+ RG S +SP ++ Sbjct: 2754 DASGT-------TPSSAHSTTSGRGE---------------------STTSRISPGSTEI 2785 Query: 1878 Q-LPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVA--CGPAQGSPGGV 1934 LPG GL E + S PR + L ++ V ++ PG Sbjct: 2786 TTLPGSTTTP------GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 2839 Query: 1935 QVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASP 1994 T PA G +E++ +++ E V P T P Sbjct: 2840 HSTVSPASTTTP------------GLSEESTTVYSSSPGSTETTVFPRSTTTSVR-GEEP 2886 Query: 1995 KTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAH-------- 2046 T + P L L EE+ P P+ + L LT A Sbjct: 2887 TTFHSRPASTHTTL--FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF 2944 Query: 2047 -SRSGSEGRT--PERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLP 2103 S SGS G T P R+++ GL G+S PS +PS T +P S Sbjct: 2945 PSSSGSTGTTLSPARSTTSGL------VGES-TPS-----RLSPSSTETTTLPGSP---- 2988 Query: 2104 REDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAED 2163 T+PS ++ ++ P P L+ + + + + + G+ Sbjct: 2989 -----TTPSLSE-------KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 3036 Query: 2164 SPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLR 2223 + P S TTS +E A QG P S S+ + T T Sbjct: 3037 TTAFPDSTTTSGLS-QEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTL 3095 Query: 2224 IPEDSRKEKLWES--PGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQ 2281 +P+D+ L E+ P +++ L ++P+ + A GL T ++ P P Sbjct: 3096 LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA-GLQEESTTFQSWPSSSDTTPSPP 3154 Query: 2282 SRGAPP-------HTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDS 2334 A P H+ P P H S S + R E V + P T + Sbjct: 3155 GTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGR--SEESTTVHSSPGATGTALFPTRSA 3212 Query: 2335 PACLEGEMGTS---SKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDF- 2390 + L GE TS S E P + + T S+ T +P+ST S Sbjct: 3213 TSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV 3272 Query: 2391 --QSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEV 2448 +S + S ++H T + Q S P ST+ G + E Sbjct: 3273 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE- 3331 Query: 2449 CAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGK 2508 + +F SGPG + LP L + P Sbjct: 3332 -STTFHSGPGSTE-----------------TTLLPDNTTASGLLEASTPV---------- 3363 Query: 2509 ERPNHSRGDPSHVTQPPPA----QGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKT----- 2559 HS H T P QG ++ + PP+ T V++ T Sbjct: 3364 ----HSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGS 3419 Query: 2560 PASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREES 2619 P+S P H + GR SP + + R G L EES Sbjct: 3420 PSSTPTT--------HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG--LVEES 3469 Query: 2620 IL----PVSADVI-------SDGRGSRPSPAMAS----YAASPSHCLSVEGGPEADGEQP 2664 P S + + GRG + + +S +++PS ++ P + P Sbjct: 3470 TTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 3529 Query: 2665 PRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGASA 2724 AT + + + + +Q G +L LGE T + + Sbjct: 3530 GSTATTH--FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 3587 Query: 2725 RGFWG-PRETKALGVCKESGS------EPAEDSSRAHSRSEEGVWEENTPPLGPLG---- 2773 P T G+ ++S + PA S A S + GV EE+T G Sbjct: 3588 METTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPA-STTSSGVSEESTTSHSRPGSTHT 3646 Query: 2774 --FPETSSSPADSTTSSCLQGLPDNPDT 2799 FP+++++P S S+ P + DT Sbjct: 3647 TAFPDSTTTPGLSRHSTTSHSSPGSTDT 3674 Score = 73.9 bits (180), Expect = 3e-12 Identities = 408/1897 (21%), Positives = 608/1897 (32%), Gaps = 372/1897 (19%) Query: 1128 EEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEET 1187 EE S GPG + PS S + G PK + S A + +P +T T+ + Sbjct: 222 EESTVSHSGPGATGTTLFPSHS---ATSVFVGEPKTSPITS-ASMETTALPGSTTTAGLS 277 Query: 1188 RPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQ---PPPSR 1244 S F + P+ A ++ + G + + P+ P S+ Sbjct: 278 EKSTTFYSSPRSPDRTLSPARTTSS---GVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQ 334 Query: 1245 HDTGTPKPSGSLANTAPHGSSPTPGVG----SLLGGPGGTQAPVSHNSKDPPARQPGEFL 1300 T + GS T G++ +G + PG T+ ++ G Sbjct: 335 ESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDN----TTTSGLLE 390 Query: 1301 APVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPK 1360 A SST P ++ S ++ +P F P + K P S + F+ Sbjct: 391 ASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWP-----SSKDTSPAPSGTTSAFVK-- 443 Query: 1361 DLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLP--RSPPGTAETEP-GRAA 1417 H PS+ S+S G E P SP TA T P R+A Sbjct: 444 -----LSTTYHSSPSSTPTTHFSAS-----STTLGHSEESTPVHSSPVATATTPPPARSA 493 Query: 1418 SPPTLESSSLFPDLP--VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLL 1475 + +E S+ + P P + S + + F + K+ S P + L Sbjct: 494 TSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS--STPSTTAALA 551 Query: 1476 LEEVSPMLPS----HFPD---LSGGKVLSKTCPPE-----RTVVPGAA----------PS 1513 L S HF D +SG SK TV+P + PS Sbjct: 552 HTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPS 611 Query: 1514 LPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELGT 1573 GS + AL ++ L +K T S RS DT P + + G Sbjct: 612 PISSGSMETTALPGSTTKPGLS-EKSTTFYSSP--RSPDTTHLPASMTSS--------GV 660 Query: 1574 GTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPCP 1633 E +T H S G +T ES A PG P Sbjct: 661 SEE---------STTSHSRPGSTHTTAFPGSTTMPGLSQEST-----ASHSSPG---PTD 703 Query: 1634 ASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVC 1693 + PG + + P FH +P G+++T L + + Sbjct: 704 TTLSPGST-----------TASSLGPEYTTFHSRP----GSTETTLLPDNTTASGLLEAS 748 Query: 1694 LPEPSKQPGPQLD---AGSLAKCSPDQEL-SFPKNKEAASSQESEDSLRLLPCEQRGGFL 1749 +P S P AGS + S+P +K+ + + S + P G Sbjct: 749 MPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP 808 Query: 1750 PEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFG--ASPSHAAQGHS 1807 T R + S H +P + Q P D T G ++ SH++ H+ Sbjct: 809 SSIPTTHISARSTTSGLVEESTTYHSSPG-STQTMHFPESDTTSGRGEESTTSHSSTTHT 867 Query: 1808 AGRAGGHL-----HPTA--GRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860 A PT+ PG P SS T+ R E+ + +H Sbjct: 868 ISSAPSTTSALVEEPTSYHSSPGSTATTHFPD--SSTTSGRSEES-----------TASH 914 Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920 S+ + + P A+S +L L E T + S + + L G T G Sbjct: 915 SSQDATGTIVLP------------ARSTTSVL-LGESTTSPISSGSMETTALPGSTTTPG 961 Query: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS 1980 S TTL + G+ + +++ T P++ + Sbjct: 962 LSERSTTFHSSPRSPATTLSPASTTSSGVSEES------TTSRSRPGSTHTTAFPDSTTT 1015 Query: 1981 PG----GTDNHASVNASPKTAL------TGPTE---------GAVLLEKCKGSRAAMSLQ 2021 PG T +H+S ++ T L +GP++ G+ GS A+S Sbjct: 1016 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFG 1075 Query: 2022 EEA----------EPTPSPPSPNRESLALALTAAHSRSGSEGRT--PERASSPGLNKPLL 2069 +E+ T P S + A T HS +GS T P ++SPGL Sbjct: 1076 QESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGEST 1135 Query: 2070 ATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCR 2129 A PA + PSP S A P P ++P+ PAS Sbjct: 1136 AFQTHPAST-----HTTPSPPSTATAPVEESTTYHRSPGSTPTT-------HFPAS---- 1179 Query: 2130 DPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQG 2189 +TT +E S + S S P A + +G Sbjct: 1180 -------------------------STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 1214 Query: 2190 EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV 2249 E + S PGS T S TP S A++ + Sbjct: 1215 ESTT----SRISPGSTEITTLPGSTTTPGLS------------------EASTTFYSSPR 1252 Query: 2250 SPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSN---- 2305 SP+ + ++S G+E+ R PG + T P + YS S Sbjct: 1253 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTE 1312 Query: 2306 TARLGHREGQAVTAVPTEPPTLQGAGPDSP-ACLEGEMGTSSKEPED----PGTPETGRS 2360 T H T+V E PT + P S L E T+S E+ PG+P + ++ Sbjct: 1313 TTVFPH---STTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT 1369 Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420 G T + LG TT PSS+ S SP + T G L S Sbjct: 1370 GLP----ATLTTADLGEESTTFPSSSGSTGTKLSP------ARSTTSG-------LVGES 1412 Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480 + P+STE P P T P LS + +P P Sbjct: 1413 TPSRLSPSSTETTT----LPGSPTT-----------PSLSEKSTTFYT----SPRSPDAT 1453 Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSP 2540 PA S VS + +HS+ +H T P + + ++ + P + Sbjct: 1454 LSPATTT--------------SSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTS 1499 Query: 2541 HSQQ------LHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVD 2594 HS Q L P S T + ++ P E L P G PT Sbjct: 1500 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT-ETTLLPDDT-ITSGLVEASTPTHS 1557 Query: 2595 SPSHSEGKSNKKRGKLRGRRLREESIL----PVSADV-------------ISDGRGSRPS 2637 S G L+EES P S+D +S SRPS Sbjct: 1558 STGSLHTTLTPASSTSAG--LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPS 1615 Query: 2638 PAMASYAASPSHCL-------SVEGGPEADGEQ--PPRLATLGPGVMEGAAETDQEALCA 2688 ++ ++ S L +V P A G P R AT V+ G T + + Sbjct: 1616 STPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT---SVLVGEPTTSPISSGS 1672 Query: 2689 GETGAQKPPGDRMLCPGRMDGAALGEQPTG--QKGASARGFWGPRETKALGVCKE---SG 2743 ET A PG A L E+ T S P T + GV +E S Sbjct: 1673 TETTA---------LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1723 Query: 2744 SEPAEDSSRAH--SRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSC---LQGLPDNPD 2798 S P + A S + GV +E+T G +T+ SP +T SS +P Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG 1783 Query: 2799 TQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPV 2858 + P+ T ASG P + L P G + + K Sbjct: 1784 STETTLLPDNTT--ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDT 1841 Query: 2859 LPLP--TQPSFEEGGDPTLG-PARLPTDLSDSSSLCL 2892 +P P T +F E + G P+ PT +SS L Sbjct: 1842 MPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 1878 Score = 73.6 bits (179), Expect = 4e-12 Identities = 515/2481 (20%), Positives = 744/2481 (29%), Gaps = 409/2481 (16%) Query: 438 PQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHG 497 P+ D T +P T G + +S + +P P + P S +P TA S Sbjct: 287 PRSPDRTLSPARTTSSG--VSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHS--- 341 Query: 498 MEMLSRLPFPAGGPEWQGGSQGALGTAGKTP---GPREKLPAVRSSQGGSPALFTYNGMT 554 +P G + L TP GP SS G + + T Sbjct: 342 ------IP---------GSTDTTLSPGTTTPSSLGPEST--TFHSSPGYTKTTRLPDNTT 384 Query: 555 DPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS 614 G V SPH T SPS S T S SS S + Sbjct: 385 TSGLLEASTPVHSSTGSPHTT----------LSPSSSTTHEGEPTTFQSWPSS-KDTSPA 433 Query: 615 PANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPAD 674 P+ +S +L S P TH + + E S P H P P PA Sbjct: 434 PSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE--ESTPVHSSPVATATTPPPAR 491 Query: 675 GLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCR 734 + +EE+ H R+P T HF SS + + T Sbjct: 492 SATSGH----VEESTAYH--------------RSPGSTQTMHFPESSTTSGHSEESATFH 533 Query: 735 ----QCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGL 790 + S A LAH + L + + S G A DA A Sbjct: 534 GSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA-- 591 Query: 791 LSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNG 850 T L AG + D +TP P+ + ++ T AL G Sbjct: 592 ----TTVLPAGSTPSVLVGD-----------STPSPISSGSME-----------TTALPG 625 Query: 851 MEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKS--KAGVTPESKAPPPLPAATPDP 908 + E ++F S PR P + H S +GV+ ES P +T Sbjct: 626 STTKPGLSEKSTTFY--------SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHT- 676 Query: 909 QTPRPGDRGCPARGRPKTRSLGL-APTEAD-APSQGRQQRRGKQLKLFRKDLDSGGAAEG 966 T PG P + T S PT+ +P G + F Sbjct: 677 -TAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFH----------- 724 Query: 967 SGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPR---AAALPEETR 1023 S G + L P G P T++P + PA R + Sbjct: 725 --SRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPS 782 Query: 1024 SSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGF 1083 S R PP + + G + R ES P Sbjct: 783 SKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 842 Query: 1084 RGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAP-ANPEEPGGSRPGPGRSPQ 1142 E + T G E+ + A EEP PG + Sbjct: 843 HF--------PESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT 894 Query: 1143 ARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPET 1202 P S +G + A S + +P + TS S P + ET Sbjct: 895 THFPDSSTTSGRSEES----TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 950 Query: 1203 A----EESAPD----STEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSG 1254 + P ST F + RSP + S G+ S T + G Sbjct: 951 TALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV--------SEESTTSRSRPG 1002 Query: 1255 SLANTAPHGSSPTPGVG----SLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTA 1310 S TA S+ TPG+ + PG T + S + ++ S+ Sbjct: 1003 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDT 1062 Query: 1311 CPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCF---- 1366 P S+ SFG + F+ +P S H+ LF +G Sbjct: 1063 ALSPG--STTALSFGQESTTFHSNP-------------GSTHTTLFPDSTTSSGIVEAST 1107 Query: 1367 -LEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESS 1425 + P +P +S+S Q A P + P P A+ P ES+ Sbjct: 1108 RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS-----PPSTATAPVEEST 1162 Query: 1426 SLFPD---LPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPM 1482 + P F P + S + + F + T PS Sbjct: 1163 TYHRSPGSTPTTHF--PASSTTSGHSEKSTIFHSSPDASGTTPSS--------------- 1205 Query: 1483 LPSHFPDLSGGKVLSKTCPP---ERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKL 1539 +H G+ + P E T +PG+ + PG + S S Sbjct: 1206 --AHSTTSGRGESTTSRISPGSTEITTLPGSTTT-PGLSEASTTFYSSPRSPTTTLSPAS 1262 Query: 1540 VTEL----ESQLQRSKD-TRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTF 1594 +T L ES RS+ + + A + G E T S+ T PH T Sbjct: 1263 MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTT 1322 Query: 1595 SAADLTRVGESTAHREGAESAVATVEAVQGRPGG------TWP-CPASFHPGHAALLPCA 1647 S E T S T+ G +P PAS G A L A Sbjct: 1323 SVHG----EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTA 1378 Query: 1648 QEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSR--PPQDVCLPEPSKQPGPQL 1705 DL + P + + A ++ +GL SR P P P L Sbjct: 1379 --DLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSL 1436 Query: 1706 DAGSL----AKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTAD----- 1756 S + SPD LS + S+ES S F T+D Sbjct: 1437 SEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEP 1496 Query: 1757 -QPHRGAPAPEAFGSPAVHLAPDLAFQ--------GDGAPPL--DATWPFG----ASPSH 1801 H + EA SP A L Q GD L D T G ++P+H Sbjct: 1497 TTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH 1556 Query: 1802 AAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHP 1861 ++ G +AG E F +SS T P PV VS T+ Sbjct: 1557 SSTGSLHTTLTPASSTSAGLQE-ESTTFQSWPSSSDTTPSPPGTTAAPVE----VSTTYH 1611 Query: 1862 SRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGK 1921 SR S P + LG E + S P G G + + Sbjct: 1612 SRPSSTPTTH-------------FSASSTTLGRSEESTTVHSSP-----GATGTALFPTR 1653 Query: 1922 VACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKT-----QGQGTANQLQP- 1975 A G P TT P +G G G +EK+ + L P Sbjct: 1654 SATSVLVGEP-----TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPA 1708 Query: 1976 ---ENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPS 2032 +GVS T +H+ ++ TA G T + ++ S A+ S + T SP S Sbjct: 1709 STTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQE---STASHSSPGSTDTTLSPGS 1765 Query: 2033 PNRESLALALTAAHSRSGSEGRT--PERASSPGLNKPLLATGDSPAPSVGDLAACAPSPT 2090 SL T HS GS T P+ ++ GL L A P + Sbjct: 1766 TTASSLGPESTTFHSSPGSTETTLLPDNTTASGL-----------------LEASTPVHS 1808 Query: 2091 SAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDP-PGPQQLLAC--------- 2140 S +L P + S + G + PS +D P P + Sbjct: 1809 STGSPHTTLSP--------AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSH 1860 Query: 2141 -SPAWAPLEEADGVQATTDTGAEDSPV--APPSLTTSPCDPKEALAGCLLQG---EGSPL 2194 SP+ P T E + V +P + T+P + +G + + SP Sbjct: 1861 GSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPG 1920 Query: 2195 EDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPED--SRKEKLWESPGRATSPPLAGAVSPS 2252 + P S +A + T ST S L E P S P S Sbjct: 1921 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP------GS 1974 Query: 2253 VAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHR 2312 A SST +G ++ D P + + G S+ SP ++ + Sbjct: 1975 TATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETT 2034 Query: 2313 EGQAVTAVP--TEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTC 2370 T P +E T + P SPA T+S + T R G+T Sbjct: 2035 ALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPD 2094 Query: 2371 PSTGLGLGR--TTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPA 2428 +T GL R TT+ SS S + P S + GP Q S P Sbjct: 2095 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS----------GP---SQESTTSHSSPG 2141 Query: 2429 STENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPL 2488 ST+ G E + +F S PG S H P + A+ Sbjct: 2142 STDTALSPGSTTALSFGQE--STTFHSSPG-STHTTL--FPDSTTSSGIVEASTRVHSST 2196 Query: 2489 EPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEV------LRAPGSPHS 2542 P S + G+ + +H T PP+ + V R+PGS + Sbjct: 2197 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 2256 Query: 2543 QQLHPPSPTEHEVDVKTP-ASKPRPDQAREDELHPKQAEKREGRRWRREP------TVDS 2595 S T + T S P H + + E R P T+ Sbjct: 2257 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 2316 Query: 2596 PSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGR---GSRPSPAMASYAASPSHCLS 2652 + + G S R ++ P S + G SR P SP+ Sbjct: 2317 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA---- 2372 Query: 2653 VEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAAL 2712 +T PG+ E + + + ET + P + Sbjct: 2373 ---------------STTTPGLSEESTTVYSSSPGSTET---------TVFPRTPTTSVR 2408 Query: 2713 GEQPT--GQKGASARGFWGPRETKALGVCKES----GSEPAEDSSRAHSRSEEGVWEENT 2766 GE+PT + AS ++ G+ +ES GS + + + + + EE+T Sbjct: 2409 GEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEEST 2468 Query: 2767 PPLGPLGFPETSSSPADSTTS 2787 G T+ SPA STTS Sbjct: 2469 TFPSSSGSTGTTLSPARSTTS 2489 Score = 63.2 bits (152), Expect = 5e-09 Identities = 148/693 (21%), Positives = 218/693 (31%), Gaps = 76/693 (10%) Query: 1903 SPPRVNPSGLEGGTVEGGKVACGPAQGS------PGGVQVTTLPAVAGHQLGLEADGHWG 1956 +P R++PS E T+ G ++ S P T PA G+ + Sbjct: 4053 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS-GVSEES--- 4108 Query: 1957 LLGQAEKTQGQGTANQLQPEN----GVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCK 2012 +Q T P++ G+S T +H+S ++ T G T + L ++ Sbjct: 4109 ---STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ-- 4163 Query: 2013 GSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATG 2072 S S + E T P L A T HS +GS T ASS +T Sbjct: 4164 -STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTT 4222 Query: 2073 DSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPS---RAQGGLGGQLPASPSCR 2129 PS D PSP S +P + P ++P+ A G+ S + Sbjct: 4223 FQSWPSSSD---TTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVH 4279 Query: 2130 DPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQG 2189 PG A A P A V T SP++ S T+ AG L Sbjct: 4280 SSPG-----ATGTALFPTRSATSVLVGEPT---TSPISSGSTETTALPGSTTTAG--LSE 4329 Query: 2190 EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV 2249 + + P ++S + T SG + E+S T+ P + Sbjct: 4330 KSTTFYSSPRSPDTTLSPASTTSSG---------VSEESTTSHSRPGSMHTTAFP-SSTT 4379 Query: 2250 SPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRG-HSSYSPSNTAR 2308 P V+ +T S+P + PG S P T P ++ P NT Sbjct: 4380 MPGVSQESTASHSSPGSTDTTLS---PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA 4436 Query: 2309 LGHREGQAVTAVPTEPP--TLQGAGPDSPACLEGEMGTSSKEPEDPGT---PETGRSGAT 2363 G E T P TL AG + +GE T P T P T S Sbjct: 4437 SGLLEASTPVHSSTGSPHTTLSPAGSTT---RQGESTTFQSWPNSKDTTPAPPTTTSAFV 4493 Query: 2364 KMPRV------TCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLK 2417 ++ + P+T TT S S SP A+ TP L Sbjct: 4494 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPV----ATATTPSPARSTTSGLV 4549 Query: 2418 QRSRGYKKKPAST------ENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHP 2471 + S Y P ST E+ G+ + + S P + + + Sbjct: 4550 EESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH 4609 Query: 2472 GAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDP--SHVTQPPPAQG 2529 +P + P +++ P S T P + G Sbjct: 4610 SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSG 4669 Query: 2530 SKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPAS 2562 S E PGS + L S T H TP + Sbjct: 4670 SMETTALPGSTTTPGLSEKSTTFHSSPSSTPTT 4702 Score = 60.8 bits (146), Expect = 2e-08 Identities = 336/1610 (20%), Positives = 498/1610 (30%), Gaps = 303/1610 (18%) Query: 1128 EEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEET 1187 EEP PG + P S +G + A S + +P + TS Sbjct: 3520 EEPTSYHSSPGSTATTHFPDSSTTSGRSEES----TASHSSQDATGTIVLPARSTTSVLL 3575 Query: 1188 RPSLDFPQEAKEPETA----EESAPD----STEFTEALRSPPAACAGEMGASPGLLIPEQ 1239 S P + ET + P ST F + RSP + S G+ Sbjct: 3576 GESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGV----- 3630 Query: 1240 PPPSRHDTGTPKPSGSLANTAPHGSSPTPGVG----SLLGGPGGTQAPVSHNSKDPPARQ 1295 S T + GS TA S+ TPG+ + PG T + S Sbjct: 3631 ---SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSS 3687 Query: 1296 PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL 1355 + ++ S+ P S+ SFG + F+ P S H+ L Sbjct: 3688 QESTTSHSSSGSTDTALSPG--STTALSFGQESTTFHSSP-------------GSTHTTL 3732 Query: 1356 FLGPKDLAGCF-----LEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAE 1410 F +G + P +P +S+S Q A P + P Sbjct: 3733 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS--- 3789 Query: 1411 TEPGRAASPPTLESSSLFPD---LPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSD 1467 P A+ P ES++ P F P + S + + F + T PS Sbjct: 3790 --PPSTATAPVEESTTYHRSPGSTPTTHF--PASSTTSGHSEKSTIFHSSPDASGTTPSS 3845 Query: 1468 PPYPSF----LLLEEVSP------MLPSHF--PDLSGGKVLSKTCP--PERTVVPGAAPS 1513 + +SP LP P LS + P P T+ P + S Sbjct: 3846 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTS 3905 Query: 1514 LPGKGS---------GCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAE 1564 L G G G + + +S S + + T + S S +T PR + Sbjct: 3906 L-GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPR--STTT 3962 Query: 1565 SVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQG 1624 SV R E T P+ T T ED+ + + LT ESTA Sbjct: 3963 SVRREEPTTFHSRPASTHTTLFT---EDS-TTSGLTE--ESTAF---------------- 4000 Query: 1625 RPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEG 1684 PG PAS G A L A DL + P + + A ++ +GL Sbjct: 4001 -PGS----PASTQTGLPATLTTA--DLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST 4053 Query: 1685 DSR--PPQDVCLPEPSKQPGPQLDAGSL----AKCSPDQELSFPKNKEAASSQESEDSLR 1738 SR P P P L S + SPD LS + S+ES S Sbjct: 4054 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS-H 4112 Query: 1739 LLPCEQRGGFLPEP----GTADQP---HRGAPAPEAFGSPAVHLAPDLAFQ--------G 1783 P P+ G + +P H + EA SP A L Q G Sbjct: 4113 SQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 4172 Query: 1784 DGAPPL--DATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGF---EGNEFAPAGASSLT 1838 D L D T G + S G L P + E F +SS T Sbjct: 4173 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDT 4232 Query: 1839 APRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELT 1898 P VPV VS T+ SR S P + LG E + Sbjct: 4233 TPSPPSTTAVPVE----VSTTYHSRPSSTPTTH-------------FSASSTTLGRSEES 4275 Query: 1899 PAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958 S P G G + + A G P TT P +G G Sbjct: 4276 TTVHSSP-----GATGTALFPTRSATSVLVGEP-----TTSPISSGSTETTALPGSTTTA 4325 Query: 1959 GQAEKT-----QGQGTANQLQP----ENGVSPGGTDNHASVNASPKTALTGPTE------ 2003 G +EK+ + L P +GVS T +H+ + TA T Sbjct: 4326 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQ 4385 Query: 2004 ---------GAVLLEKCKGSRAAMSLQEEA----------EPTPSPPSPNRESLALALTA 2044 G+ GS A SL E+ E T P + L A T Sbjct: 4386 ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTP 4445 Query: 2045 AHSRSGSE-------GRTPERASSPGLNKPLLATGDSPAPSVGDLAAC--------APSP 2089 HS +GS G T + S + +PAP A +PS Sbjct: 4446 VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSS 4505 Query: 2090 TSAAHMPCSLGPLPREDP-----------LTSPSRAQGGLGGQLPASPSCRDPPGPQQLL 2138 T H S L R + T+PS A+ G + S + PG Q + Sbjct: 4506 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTM 4565 Query: 2139 ACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPS 2198 ++ T +G + S TT + L+ E+P+ Sbjct: 4566 HFP------------ESNTTSGRGEESTTSHSSTTHTISSAPSTTSALV-------EEPT 4606 Query: 2199 SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRAT 2258 S+ S T TH D+ S R E + ++ G P + + +V Sbjct: 4607 SYHSSPGSTAT-THFPDSSTTSG-RSEESTASHSSQDATGTIVLPARS-----TTSVLLG 4659 Query: 2259 GLSSTPTGDEAQAGRGLPG----PDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREG 2314 +++P + LPG P + H++P P H S S + R Sbjct: 4660 ESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGR-----S 4714 Query: 2315 QAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTG 2374 + T V + P + + G + S+ PG+ +T + ST Sbjct: 4715 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPES--------STA 4766 Query: 2375 LGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDL--------KQRSRGYKKK 2426 G + S +++ SP S +A + P P + S ++ Sbjct: 4767 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEES 4826 Query: 2427 PASTENGQWKGQAP---HGPVTCEVC-AASFRSGPGLSRHKARKHRPHPGAPAEPSPAAL 2482 AS + G P H + + + +F PG PG A+ + Sbjct: 4827 TASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYS 4886 Query: 2483 PAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPA--------------- 2527 ++ P + L+ P S +SG+ +S+ + +H T P + Sbjct: 4887 SSRSPDQTLS----PASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHS 4942 Query: 2528 -QGSKEVLRAPGSPHSQQLHPPSPTEHE-----VDVKTPASKPRPDQARE 2571 GS E +PGS + T H + +PAS P + E Sbjct: 4943 KPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992 Score = 59.3 bits (142), Expect = 7e-08 Identities = 167/726 (23%), Positives = 231/726 (31%), Gaps = 121/726 (16%) Query: 23 VASSPGHPSQPPLEDNTPATRTTKGAREAG-------GQAQAMELPEAQPRQARDGELK- 74 V SSP + P +PA TT G E G Q M PE+ R E + Sbjct: 1887 VHSSPVATATTP----SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942 Query: 75 -----------PPSLRG---QAPSSTPGKRGSP--------QTPPGRSPLQAPSRLAGRA 112 PPS + P+S GS T GRS S + A Sbjct: 1943 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 2002 Query: 113 EGSPPQRYILGIASSRTKPTLDETPENP----QLEAAQLPEVDTPQG---PGTGAPLRPG 165 G+ I+ A S T L E+ +P +E LP T G T P Sbjct: 2003 TGT-----IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR 2057 Query: 166 LPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYP 225 P T PA+ S ++T+++ P +T P + G S S+ Sbjct: 2058 SPATTLSPASTT-------SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 2110 Query: 226 EYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGAS- 284 ++ P + S P + P PG S +SF H + Sbjct: 2111 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPG-STTALSFGQESTTFHSSPG 2169 Query: 285 ---TKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPT-QPAPSPLPCYQG 340 T FP T+ +V A V + P T PA S P QG Sbjct: 2170 STHTTLFPDST-----TSSGIVEA---------STRVHSSTGSPRTTLSPASSTSPGLQG 2215 Query: 341 QPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSS 400 + H + SP + +AP S + H+S P P +T P SS Sbjct: 2216 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS-----PGSTP-------TTHFPASS 2263 Query: 401 LPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGP----L 456 H S D S P + + P + T PG L Sbjct: 2264 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL 2323 Query: 457 AATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSP---HGMEMLSRLPFPAGGPEW 513 + + F++ SP L L + T+R P H + P E Sbjct: 2324 SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 2383 Query: 514 QGGSQGALGTAGKTPGPREKLPAVRSSQ----GGSPA-----LFTYNGMTDPGAQPLFFG 564 + G+ T PR +VR + PA LFT + T + Sbjct: 2384 TTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAF 2443 Query: 565 VAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT----AGSTCSSL----SPMSSSPA 616 P + G P+ +G + P S +T T A ST S L +P SP+ Sbjct: 2444 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS 2503 Query: 617 NPSSEESQLPG-PLGPS------AFFHPPTHPQETGSP---FPSPEPPHSLPTHYQPEPA 666 S+E + LPG P PS F+ P P T SP S S +H QP Sbjct: 2504 --STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGST 2561 Query: 667 KAFPFP 672 FP Sbjct: 2562 HTTAFP 2567 Score = 54.7 bits (130), Expect = 2e-06 Identities = 171/743 (23%), Positives = 235/743 (31%), Gaps = 122/743 (16%) Query: 7 RGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAG-------GQAQAME 59 R APP T + ++P +S G PS P + A TT G E G Q M Sbjct: 787 RPAPPTTTSAFVEPS--TTSHGSPSSIPTT-HISARSTTSGLVEESTTYHSSPGSTQTMH 843 Query: 60 LPEAQPRQARDGELKPPSLR-----GQAPSSTPGKRGSP----QTPPGRSPLQAP--SRL 108 PE+ R E APS+T P +P + P S Sbjct: 844 FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT 903 Query: 109 AGRAEGSPPQRY-------ILGIASSRTKPTLDETPENP----QLEAAQLPEVDTPQGPG 157 +GR+E S I+ A S T L E+ +P +E LP T G Sbjct: 904 SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS 963 Query: 158 TGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGP------P 211 + PR+ A + P+S TS+ + S T R PG P Sbjct: 964 ERSTTFHSSPRSPATTLS------------PASTTSSGVSEESTTSRS-RPGSTHTTAFP 1010 Query: 212 QSRGTSPLQPGSYPEYQASGADSW---PPAAENSFPGANFGVPPAEPEPIPKGSRPGGSP 268 S T L S + + G+ P + S P + PG S Sbjct: 1011 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPG-ST 1069 Query: 269 RGVSFQFPFPALHG----ASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAY 324 +SF H T FP T+ +V A V + Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDST-----TSSGIVEA---------STRVHSSTGS 1115 Query: 325 PLPT-QPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPER 383 P T PA S P QG+ H + SP + +AP S + H+S P Sbjct: 1116 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS-----PGS 1170 Query: 384 PPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDP 443 P +T P SS H S D S P + + P Sbjct: 1171 TP-------TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 1223 Query: 444 TAAPYPTPPGGP----LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSP---H 496 + T PG L+ + F++ SP L L + T+R P H Sbjct: 1224 GSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH 1283 Query: 497 GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQ----GGSPA-----L 547 + P E + G+ T P +V + PA L Sbjct: 1284 STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTL 1343 Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT----AGS 603 FT + T + P + G P+ +G + P S +T T A S Sbjct: 1344 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARS 1403 Query: 604 TCSSL----SPMSSSPANPSSEESQLPG-PLGPS------AFFHPPTHPQETGSP---FP 649 T S L +P SP+ S+E + LPG P PS F+ P P T SP Sbjct: 1404 TTSGLVGESTPSRLSPS--STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 1461 Query: 650 SPEPPHSLPTHYQPEPAKAFPFP 672 S S +H QP FP Sbjct: 1462 SGVSEESSTSHSQPGSTHTTAFP 1484 Score = 53.5 bits (127), Expect = 4e-06 Identities = 160/714 (22%), Positives = 232/714 (32%), Gaps = 106/714 (14%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELP 61 PG P T T ++ + + P+ +T T T+ + +G ++ P Sbjct: 2391 PGSTETTVFPRTPTTSVRGEEPTTFHSRPA------STHTTLFTEDSTTSGLTEESTAFP 2444 Query: 62 EAQPRQARDGELKPPSLR----GQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPP 117 P + G P +L G+ ++ P GS T SP A S +G S P Sbjct: 2445 -GSPASTQTG--LPATLTTADLGEESTTFPSSSGSTGTT--LSP--ARSTTSGLVGESTP 2497 Query: 118 QRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEE 177 R SS TL +P P L +P+ P A L P T + +EE Sbjct: 2498 SRLS---PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD--ATLSPAT--TTSSGVSEE 2550 Query: 178 LGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPP 237 +ST+++ P +T P + G S S+ ++ P Sbjct: 2551 --------------SSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2596 Query: 238 AAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGAS----TKPFPADVA 293 + S P + P PG S +SF H + T FP Sbjct: 2597 STTTSGPSQESTTSHSSPGSTDTALSPG-STTALSFGQESTTFHSSPGSTHTTLFPDST- 2654 Query: 294 GHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPT-QPAPSPLPCYQGQPGGLNRHSDLS 352 T+ +V A V + P T PA S P QG+ H + Sbjct: 2655 ----TSSGIVEA---------STRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAST 2701 Query: 353 GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYR 412 SP + +AP S + H+S P P +T P SS H Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRS-----PGSTP-------TTHFPASSTTSGHSEKSTIF 2749 Query: 413 ASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGP----LAATRSMFFNGQP 468 S D S P + + P + T PG L+ + F++ Sbjct: 2750 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 2809 Query: 469 SPGQRLCLPQSAPLPWPQVLPTARPSP---HGMEMLSRLPFPAGGPEWQGGSQGALGTAG 525 SP L L + T+R P H + P E + G+ Sbjct: 2810 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 2869 Query: 526 KTPGPREKLPAVRSSQ----GGSPA-----LFTYNGMTDPGAQPLFFGVAQPQVSPHGTP 576 T PR +VR + PA LFT + T + P + G P Sbjct: 2870 TTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 2929 Query: 577 SLPPPRVVGASPSESPLPSPATNT----AGSTCSSL----SPMSSSPANPSSEESQLPG- 627 + +G + P S +T T A ST S L +P SP+ S+E + LPG Sbjct: 2930 ATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS--STETTTLPGS 2987 Query: 628 PLGPS------AFFHPPTHPQETGSP---FPSPEPPHSLPTHYQPEPAKAFPFP 672 P PS F+ P P T SP S S +H QP FP Sbjct: 2988 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP 3041 Score = 52.0 bits (123), Expect = 1e-05 Identities = 164/735 (22%), Positives = 237/735 (32%), Gaps = 139/735 (18%) Query: 23 VASSPGHPSQPPLEDNTPATRTTKGAREAG-------GQAQAMELPEAQPRQARDGELKP 75 V SSP + P +PA TT G E G Q M PE+ R E Sbjct: 3444 VHSSPVATATTP----SPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 3499 Query: 76 PSLR-----GQAPSSTPGKRGSP----QTPPGRSPLQAP--SRLAGRAEGSPPQRY---- 120 APS+T P +P + P S +GR+E S Sbjct: 3500 SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 3559 Query: 121 ---ILGIASSRTKPTLDETPENP----QLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQP 173 I+ A S T L E+ +P +E LP G+ PGL Sbjct: 3560 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALP----------GSTTTPGL------- 3602 Query: 174 AAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGS-----YPEYQ 228 + + FH + P ++ + + TS G + TS +PGS +P+ Sbjct: 3603 SEKSTTFHSSPRSPATTLSPASTTSS---------GVSEESTTSHSRPGSTHTTAFPDST 3653 Query: 229 ASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF 288 + S +S PG+ + +P + GS + + ST Sbjct: 3654 TTPGLSRHSTTSHSSPGST------DTTLLPASTTTSGSSQESTTSHS----SSGSTDTA 3703 Query: 289 PADVAGHAFTNGPLVFAFHQPQGA-----WPEEAVGTG-----------PAYPLPT-QPA 331 + + A + G FH G+ +P+ +G P T PA Sbjct: 3704 LSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 3763 Query: 332 PSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGL 391 S P QG+ H + SP + +AP S + H+S P P Sbjct: 3764 SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS-----PGSTP------ 3812 Query: 392 GSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTP 451 +T P SS H S D S P + + P + T Sbjct: 3813 -TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 3871 Query: 452 PGGP----LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSP---HGMEMLSRL 504 PG L+ + F++ SP L L + T+R P H + Sbjct: 3872 PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAST 3931 Query: 505 PFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQ----GGSPA-----LFTYNGMTD 555 P E + G+ T PR +VR + PA LFT + T Sbjct: 3932 TTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTS 3991 Query: 556 PGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT----AGSTCSSL--- 608 + P + G P+ +G + P S +T T A ST S L Sbjct: 3992 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGE 4051 Query: 609 -SPMSSSPANPSSEESQLPG-PLGPS------AFFHPPTHPQETGSP---FPSPEPPHSL 657 +P SP+ S+E + LPG P PS F+ P P T SP S S Sbjct: 4052 STPSRLSPS--STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 4109 Query: 658 PTHYQPEPAKAFPFP 672 +H QP FP Sbjct: 4110 TSHSQPGSTHTTAFP 4124 Score = 52.0 bits (123), Expect = 1e-05 Identities = 271/1338 (20%), Positives = 423/1338 (31%), Gaps = 219/1338 (16%) Query: 1135 PGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFP 1194 P SP +G S + +T A+ P P P++ T S + P+ FP Sbjct: 3762 PASSTSPGLQGESTAFQTHPASTHTTPS----PPSTATAPVEESTTYHRSPGSTPTTHFP 3817 Query: 1195 QEA-----KEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGT 1249 + E T S+PD++ T + S + +G ++ + P + T Sbjct: 3818 ASSTTSGHSEKSTIFHSSPDASGTTPS--SAHSTTSGRGESTTSRISPGSTEITTLPGST 3875 Query: 1250 PKPSGSLANTAPHGSSPTP------------GVG----SLLGGPGGTQAPVSHNSKDPPA 1293 P S A+T + S +P GVG + PG T + VS S P Sbjct: 3876 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 3935 Query: 1294 RQPGEFLAPVANPSSTACP------KPSVLSSKISSFGCDPAG-----FNRDPLGVPVAK 1342 ++P ST SV + ++F PA F D + + Sbjct: 3936 LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTE 3995 Query: 1343 KGPQPYSSPHSELFLGPKDLAGCFL-EELHPKPSARDAP-----PASSSCLCQDGEDAGS 1396 + SP S P L L EE PS+ + PA S+ GE S Sbjct: 3996 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS 4055 Query: 1397 LEPQLPRSPPGTAETE--PGRAASPPTLESSSLF---PDLPVDRFDPPLYGSLSANRDSG 1451 R P + ET PG +P E S+ F P P P S + +S Sbjct: 4056 ------RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 4109 Query: 1452 LPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD--LSGGKVLSK----------- 1498 + T D S L E + + LS G + Sbjct: 4110 TSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHS 4169 Query: 1499 -------TCPPERTVVPGAAP-SLPGKGSGCSV-ALMSHLSEDELEIQKLVTELESQLQR 1549 T P+ T+ G S P S S+ ++ S +Q+ T +S Sbjct: 4170 SPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSS 4229 Query: 1550 SKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTA-H 1608 S T P A V + P+ + +T L R EST H Sbjct: 4230 SDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTT----------LGRSEESTTVH 4279 Query: 1609 REGAESAVA---TVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFH 1665 + A T A G P S LP + + A S + F+ Sbjct: 4280 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS----TTTAGLSEKSTTFY 4335 Query: 1666 FQP------VQKAGASKTGLCQAE--GDSRPPQ--DVCLPEPSKQPGPQLD--AGSLAKC 1713 P + A + +G+ + SRP P + PG + A + Sbjct: 4336 SSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPG 4395 Query: 1714 SPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQP-HRGAPAPEAFGSPA 1772 S D LS P + A+S + P LP+ TA P + GSP Sbjct: 4396 STDTTLS-PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPH 4454 Query: 1773 VHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTA-GRPGFEGNEFAP 1831 L+P + G +WP + A ++ A L T+ G P Sbjct: 4455 TTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS--AFVELSTTSHGSPS--STPTTH 4510 Query: 1832 AGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVA------ 1885 ASS T R E+ V A + P+R + + PG Sbjct: 4511 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 4570 Query: 1886 -----KSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLP 1940 + ++ T S P + +E T SPG T P Sbjct: 4571 NTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT---------SYHSSPGSTATTHFP 4621 Query: 1941 -----------AVAGHQLGLEADGHWGLLGQAEKTQ----GQGTANQLQ---------PE 1976 + A H D ++ A T G+ T + + P Sbjct: 4622 DSSTTSGRSEESTASHS---SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 4678 Query: 1977 NGVSPGGTDNHASVNASPK-TALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNR 2035 + +PG ++ + ++SP T T + + L + + S S TPSP Sbjct: 4679 STTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 4738 Query: 2036 ESLALALTAAHSRSGSEGRT--PERASSPGLNKPLLATGDSPAPSVGD----LAACAPSP 2089 L TA HS GS PE +++ G ++ + S ++ +A P Sbjct: 4739 SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP 4798 Query: 2090 TS---------AAHMPCSLGPLPREDPLTS-----------PSRAQGGLGGQLPASPSCR 2129 TS H P S R + T+ P A G++ S + Sbjct: 4799 TSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFY 4858 Query: 2130 DPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQG 2189 PG + S A P A + + + D ++P S+T+S + G Sbjct: 4859 ISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSS-----------ISG 4907 Query: 2190 EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV 2249 E + L + + + T SG + + +T S + L SPG T+ A Sbjct: 4908 EPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTL--SPGSITTSSFAQEF 4965 Query: 2250 SPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSR---GAPPHTNPDRMPRGHSSYSPSNT 2306 + + + LS+ + A +PG +S +P T +++S SNT Sbjct: 4966 TTPHSQPGSALSTV-----SPASTTVPGLSEESTTFYSSPGSTET-------TAFSHSNT 5013 Query: 2307 ARLGHREGQAVTAVPTEP 2324 + Q T P P Sbjct: 5014 MSI---HSQQSTPFPDSP 5028 Score = 43.9 bits (102), Expect = 0.003 Identities = 167/715 (23%), Positives = 234/715 (32%), Gaps = 109/715 (15%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELP 61 P G+P T++ + S S P +D TPA TT A +EL Sbjct: 4445 PVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA--------FVELS 4496 Query: 62 EAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYI 121 + P+ A S+T G R T SP +A SP + Sbjct: 4497 TT----SHGSPSSTPTTHFSASSTTLG-RSEESTTVHSSP------VATATTPSPARSTT 4545 Query: 122 LGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFH 181 G+ T T +P + Q PE +T G G + A Sbjct: 4546 SGLVEEST--TYHSSPGSTQ--TMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTS-- 4599 Query: 182 RCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAEN 241 E P+S+ ++SP +T P + G S S+ A+G P + Sbjct: 4600 -ALVEEPTSY----HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 4654 Query: 242 SFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGP 301 S P + + PG + P L ST F + + T+ Sbjct: 4655 SVLLGESTTSPISSGSMETTALPGSTTT--------PGLSEKST-TFHSSPSSTPTTH-- 4703 Query: 302 LVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAA 361 F+ EE+ T + P+ T PSP + GL S + SSPG+ Sbjct: 4704 --FSASSTTLGRSEEST-TVHSSPVATATTPSPA---RSTTSGLVEES--TAYHSSPGST 4755 Query: 362 HSAPRPFSDSL----------HKSLTKILPERPPSAQDGL----GSTRGPPSSLPQRHFP 407 + P S + H S T + PPS L S P S+ HFP Sbjct: 4756 QTMHFPESSTASGRSEESRTSHSSTTHTI-SSPPSTTSALVEEPTSYHSSPGSIATTHFP 4814 Query: 408 GQAY---RASGVDTSPGPPDTELAAPGP----PPARL---------PQLWDPTAAPYPTP 451 + R+ S PDT P P R+ P + T A T Sbjct: 4815 ESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT 4874 Query: 452 PGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP 511 PG L+A ++ ++ SP Q L P S PT+ S E FPA Sbjct: 4875 PG--LSAKSTILYSSSRSPDQTLS-PASMTSSSISGEPTSLYSQ--AESTHTTAFPA-ST 4928 Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571 G SQ + T PG E S G T P +QP G A VS Sbjct: 4929 TTSGLSQEST-TFHSKPGSTE----TTLSPGSITTSSFAQEFTTPHSQP---GSALSTVS 4980 Query: 572 PHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPSSEESQLPGPL 629 P T ++P + SP + T + S S+ S+ P +P + LP L Sbjct: 4981 PAST-TVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATL 5039 Query: 630 ------GPSAFFHPPTHPQETGSPFPSPEPPHSL---PT--HYQPEPAKAFPFPA 673 S FH + T +P P+ L PT + P P FPA Sbjct: 5040 TTTDIGQESTAFHSSSDATGT-TPLPARSTASDLVGEPTTFYISPSPTYTTLFPA 5093 Score = 42.7 bits (99), Expect = 0.007 Identities = 151/724 (20%), Positives = 231/724 (31%), Gaps = 141/724 (19%) Query: 6 PRGAPPPTMTGDLQPRQVASS-------PGHPSQPPLEDNT---------------PATR 43 P G+ P + GD P ++S PG ++P L + + PA+ Sbjct: 596 PAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASM 655 Query: 44 TTKGAREAGGQAQAMELPEAQPRQARDGELKPPSL--RGQAPSSTPGKRGSPQTPPGRSP 101 T+ G E + + P + A G P L A S+PG + +P + Sbjct: 656 TSSGVSEESTTSHSR--PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTT- 712 Query: 102 LQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAP 161 A P+ T+ TL P+N A+ L E P T +P Sbjct: 713 ----------ASSLGPEYTTFHSRPGSTETTL--LPDN--TTASGLLEASMPVHSSTRSP 758 Query: 162 LRPGLPRTEAQPAAEELGFH-----RCFQEPPSSFTS-------TNYTSPSATP------ 203 P E FH + + P + TS T++ SPS+ P Sbjct: 759 HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 818 Query: 204 RPPAPGPPQSRGTSPLQPGS-----YPEYQASGADSWPPAAENSFPGANFGVPPAE---- 254 R G + T PGS +PE + +S P+ Sbjct: 819 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSAL 878 Query: 255 -PEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313 EP S PG + + FP + ++ A + T G +V P + Sbjct: 879 VEEPTSYHSSPGST---ATTHFPDSSTTSGRSEESTASHSSQDAT-GTIVL----PARST 930 Query: 314 PEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAA------HSAPRP 367 +G P+ + G + L G+ ++PG + HS+PR Sbjct: 931 TSVLLGESTTSPISS---------------GSMETTALPGSTTTPGLSERSTTFHSSPRS 975 Query: 368 FSDSLHKSLTKI--LPERPPSAQDGLGSTRGPPSSLP-QRHFPGQAYRASGVDTSPGPPD 424 + +L + T + E +++ GST ++ P PG + ++ +SPG D Sbjct: 976 PATTLSPASTTSSGVSEESTTSRSRPGSTH--TTAFPDSTTTPGLSRHSTTSHSSPGSTD 1033 Query: 425 TEL-----AAPGPPPARLPQLWDPTAAPYPTPPGGPLAAT---RSMFFNGQPSPGQRLCL 476 T L GP + PG A + S F+ P Sbjct: 1034 TTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLF 1093 Query: 477 PQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGS---QGALGTAGKTPGPREK 533 P S T S G + P + P QG S Q + TP P Sbjct: 1094 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP--- 1150 Query: 534 LPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSL---PPPRVVGASPSE 590 S +P + PG+ P A S H S P G +PS Sbjct: 1151 -----PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 1205 Query: 591 SPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPL-------GPSAFFHPPTHPQE 643 + S + ST S +SP S+E + LPG + F+ P P Sbjct: 1206 A--HSTTSGRGESTTSRISP-------GSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 1256 Query: 644 TGSP 647 T SP Sbjct: 1257 TLSP 1260 Score = 37.0 bits (84), Expect = 0.39 Identities = 155/699 (22%), Positives = 227/699 (32%), Gaps = 126/699 (18%) Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELP 61 P G+P T++ + S S P +D TPA TT A +EL Sbjct: 3362 PVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA--------FVELS 3413 Query: 62 EAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYI 121 + P+ A S+T G R T SP +A SP + Sbjct: 3414 TT----SHGSPSSTPTTHFSASSTTLG-RSEESTTVHSSP------VATATTPSPARSTT 3462 Query: 122 LGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFH 181 G+ T T +P + Q PE DT G G + A Sbjct: 3463 SGLVEEST--TYHSSPGSTQ--TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTS-- 3516 Query: 182 RCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAEN 241 E P+S+ ++SP +T P + G S S+ A+G P + Sbjct: 3517 -ALVEEPTSY----HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 3571 Query: 242 SFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGP 301 S P + + PG + P L ST F + A T P Sbjct: 3572 SVLLGESTTSPISSGSMETTALPGSTTT--------PGLSEKST-TFHSSPRSPATTLSP 3622 Query: 302 LVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAA 361 A G E ++ P + P P GL+RHS S SSPG+ Sbjct: 3623 ---ASTTSSGVSEESTT----SHSRPGSTHTTAFPDSTTTP-GLSRHSTTSH--SSPGST 3672 Query: 362 HSAPRPFSDSLHKSL--------------TKILPERPPSAQDGLGST--RGPPSSLPQRH 405 + P S + S T + P + G ST P S Sbjct: 3673 DTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 3732 Query: 406 FP------GQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAAT 459 FP G ++ V +S G P T L+ P + P L + A + T P A+T Sbjct: 3733 FPDSTTSSGIVEASTRVHSSTGSPRTTLS---PASSTSPGLQGESTA-FQTHP----AST 3784 Query: 460 RSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPA-----GGPEWQ 514 + PSP P + + P + P+ H FPA G E Sbjct: 3785 HT-----TPSPPSTATAPVEESTTYHR-SPGSTPTTH---------FPASSTTSGHSEKS 3829 Query: 515 GGSQGALGTAGKTPGPREKLPAVRSS------QGGSPALFTYNGMTDPGAQPLFFGVAQP 568 + +G TP + R GS + T G T G+++ Sbjct: 3830 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP------GLSEA 3883 Query: 569 QVSPHGTPSLPPPRVVGASPSESPLPSPATNT---AGSTCSSLSPMSSSPANPSSEE--- 622 + + +P P + AS + + +T + GST S++SP S++ S E Sbjct: 3884 STTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTV 3943 Query: 623 -SQLPGPLGPSAFFHPPTHPQETGSPFPSPEPP--HSLP 658 S PG + F P+ T + EP HS P Sbjct: 3944 YSSSPGSTETTVF------PRSTTTSVRREEPTTFHSRP 3976 Score = 34.3 bits (77), Expect = 2.5 Identities = 87/423 (20%), Positives = 122/423 (28%), Gaps = 57/423 (13%) Query: 3463 PPPRGSSPI-------LSEGSLPALLHLCSEVAPSTTKGWPETL----ERPVDPVTHPIR 3511 PP ++P+ S GS P H A STT G E P T P Sbjct: 2233 PPSTATAPVEESTTYHRSPGSTPTT-HF---PASSTTSGHSEKSTIFHSSPDASGTTPSS 2288 Query: 3512 GCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPEN-EASPGSPGPLLQQALPLG 3570 S E +SP + G G E +SP SP L A Sbjct: 2289 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTS 2348 Query: 3571 ASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSE 3630 + + G V PG + + + Sbjct: 2349 LGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVR 2408 Query: 3631 GGPRGTFHKGSATKPAGCQSS--SKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTE 3688 G TFH ++PA ++ ++D + + ++ FP P T+ Sbjct: 2409 GEEPTTFH----SRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS-------------TQ 2451 Query: 3689 NGMKPATPKAKPG------PSSQGSG----SPRPGTKTG--GGSQPQPASGQLQSETATT 3736 G+ A G PSS GS SP T +G G S P S +ET T Sbjct: 2452 TGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS-STETTTL 2510 Query: 3737 PAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQG--PHGSLGPKEKGESSTKRKKGQV 3794 P P+ PS S ++ T P G S + G + T Sbjct: 2511 PGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDST 2570 Query: 3795 PGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEP 3854 P S + +P + D P+ + P S P S P Sbjct: 2571 TTPGLSRHSTTSHSSPGSTD-------TTLLPASTTTSGPSQESTTSHSSPGSTDTALSP 2623 Query: 3855 GHT 3857 G T Sbjct: 2624 GST 2626 Score = 34.3 bits (77), Expect = 2.5 Identities = 57/268 (21%), Positives = 84/268 (31%), Gaps = 17/268 (6%) Query: 3554 ASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQED 3613 +SP SP L A + + G F G PG H Sbjct: 3253 SSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH-SSP 3311 Query: 3614 HLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRK 3673 S+ S G TFH G P +++ + ++ PVH Sbjct: 3312 GSTDTTLSPGSTTASSLGPESTTFHSG----PGSTETTLLPDNTTASGLLEASTPVH--S 3365 Query: 3674 AVGS----LAP-GELARGTENGMKPATPKAK---PGPSSQGSGSPRPGTKTGGGSQPQPA 3725 + GS L+P G R E+ + P +K P P + S T + G P Sbjct: 3366 STGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPT 3425 Query: 3726 SGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGE--QGPHGSLGPKEKG 3783 + S T ++ S S + A+S T G E GS Sbjct: 3426 THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFP 3485 Query: 3784 ESSTKRKKGQVPGPARSESVGSFGRAPS 3811 ES T +G+ + S + + APS Sbjct: 3486 ESDTTSGRGEESTTSHSSTTHTISSAPS 3513 Score = 33.1 bits (74), Expect = 5.6 Identities = 139/676 (20%), Positives = 205/676 (30%), Gaps = 128/676 (18%) Query: 76 PSLRGQAPSSTPGKRGSPQTPPGRSPLQAP---SRLAGRAEGSPPQRYILGIAS----SR 128 P L+G++ + + TP S AP S R+ GS P + ++ S Sbjct: 1128 PGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSE 1187 Query: 129 TKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG------LPRTEAQPAAEELGFHR 182 +P+ + + +G T + + PG LP + P E Sbjct: 1188 KSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAS--T 1245 Query: 183 CFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENS 242 F P S T+T SP++ + G + TS QPGS + + + P +E S Sbjct: 1246 TFYSSPRSPTTT--LSPASMT---SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 1300 Query: 243 FPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFP-----ALHGASTKPF---PADVAG 294 + S RG + FP ++HG F PA Sbjct: 1301 -------------------TTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHT 1341 Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAP-----SPLPCYQGQPGGLNRHS 349 FT + A+P T P A + P G G + Sbjct: 1342 TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG-----T 1396 Query: 350 DLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGST------RGPPSSLPQ 403 LS A S+ P S + T LP P + ST R P ++L Sbjct: 1397 KLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 1456 Query: 404 RHFP--GQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAA-------PYPTPPGG 454 G + +S + PG T + L Q +PT + PG Sbjct: 1457 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQ--EPTTSHSSQGSTEATLSPGS 1514 Query: 455 PLAAT---RSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP---A 508 A++ +S F+ P + LP T S G + P A Sbjct: 1515 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA 1574 Query: 509 GGPE-------WQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPL 561 G E W S G T P E S +P T A Sbjct: 1575 GLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPT-------THFSASST 1627 Query: 562 FFGVAQPQVSPHGTP-----SLPPPR----VVGASPSESPLPSPATNTAG---------- 602 G ++ + H +P +L P R V+ P+ SP+ S +T T Sbjct: 1628 TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGL 1687 Query: 603 ---------------STCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP 647 +T S S SS + S+ PG +AF T P + Sbjct: 1688 SEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQES 1747 Query: 648 FPSPEPPHSLPTHYQP 663 S P S T P Sbjct: 1748 TASHSSPGSTDTTLSP 1763 Score = 32.7 bits (73), Expect = 7.3 Identities = 71/319 (22%), Positives = 113/319 (35%), Gaps = 35/319 (10%) Query: 3623 SSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS---KALKFPVHPRKAVGSLA 3679 ++S +V E P S P+ ++++ S +TPS K+ F PR +L+ Sbjct: 2961 TTSGLVGESTP-------SRLSPSSTETTTLPGSP-TTPSLSEKSTTFYTSPRSPDATLS 3012 Query: 3680 PGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAK 3739 P A T +G+ + + P S + + T T G SQ AS Q T T Sbjct: 3013 P---ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEAT-LS 3068 Query: 3740 PSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPAR 3799 P + S ++ + T+ + G + SST + PA Sbjct: 3069 PGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT-PAS 3127 Query: 3800 SESVG------SFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAE 3853 S S G +F PS+ D P P A P V T ++P P+ A Sbjct: 3128 STSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTT-----YHSRPSSTPTTHFSAS 3182 Query: 3854 P---GHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEP-----AEPHTHRTAEAQSDLLS 3905 G ++ + + L P + T+V EP + T TA S + Sbjct: 3183 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTA 3242 Query: 3906 QLFGQRLTGFKIPLKKDAS 3924 L + T + P D + Sbjct: 3243 GLSEKSTTFYSSPRSPDTT 3261 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 87.8 bits (216), Expect = 2e-16 Identities = 159/615 (25%), Positives = 202/615 (32%), Gaps = 123/615 (20%) Query: 11 PPTMTGDLQPRQVASSPGHPSQPPLEDNTPATR-TTKGAREAGGQAQAMELPEAQPRQAR 69 P G L V PG P PP ++ P T+ ++ + + +++L QP Q+ Sbjct: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSI 807 Query: 70 DGELKPPSLRGQAPSSTPGKRG------------------------SPQTPPGRSPLQAP 105 PPSL A PG + + +PP ++ Sbjct: 808 SQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESS 867 Query: 106 SRLAGRAEGSPPQRYILGIASSRTKPTLDET--PENPQLEAAQLPEVDTPQGPGTGAPLR 163 S + G PP + G+ T PTL T P+ P L+ ++ P PG G P Sbjct: 868 SSMPGLGMVPPPPPPLPGM----TVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP 923 Query: 164 PGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGS 223 P LP P G PP P P P PP G P Sbjct: 924 PPLPGAGILPLPPLPG---AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980 Query: 224 YPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGA 283 P GA PP PGA G+PP P P+P P P + P P L GA Sbjct: 981 LP-----GAGIPPPP---PLPGA--GIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1028 Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG 343 P P PL A P P + P P P P PLP Sbjct: 1029 GIPPPP-----------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-----GA 1072 Query: 344 GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQ 403 G+ L PGA P P + +P PP G+ PP LP Sbjct: 1073 GIPPPPPL------PGAGIPPPPPLPGA-------GIPPPPPLPGVGI----PPPPPLPG 1115 Query: 404 RHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYP---TPPGGPLAATR 460 P G P PP P PPP LP++ P P P PP PL Sbjct: 1116 AGIPPPP-PLPGAGIPPPPPLPGAGIPPPPP--LPRVGIPPPPPLPGAGIPPPPPL---- 1168 Query: 461 SMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGA 520 P G +P PLP + P P G+ + P P G Sbjct: 1169 -------PGAG----IPPPPPLPGVGIPPP--PPLPGVGIPPPPPLPGAGIP----PPPP 1211 Query: 521 LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP 580 L G P P LP + G+ P P+ PQV G+ +LP Sbjct: 1212 LPGMGIPPAPAPPLPPPGT------------GIPPPPLLPVSGPPLLPQV---GSSTLPT 1256 Query: 581 PRVVGASPSESPLPS 595 P+V G P PLPS Sbjct: 1257 PQVCGFLP--PPLPS 1269 Score = 63.2 bits (152), Expect = 5e-09 Identities = 121/427 (28%), Positives = 142/427 (33%), Gaps = 64/427 (14%) Query: 328 TQPAPSPLPCY---QGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384 +QP P P + QGQPG HS + +S HS F +S + +P P Sbjct: 808 SQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSH--EHSVSSAFKNSCN------IPSPP 859 Query: 385 P-------SAQDGLGSTRGPPSSLPQRHFPGQAYRA-------SGVDTSPGPPDTELAAP 430 P S+ GLG PP LP P A G + P PP A Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG 919 Query: 431 GPPPARLPQLWDPTAAPYP---TPPGGPLAATRSMFFNGQPSPGQRLCLPQSAP---LPW 484 PPP LP P P PP PL + P PG + LP P +P Sbjct: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPG--AAIPPPPPLPGAGIPLPPPLPGAGIPP 977 Query: 485 PQVLPTARPSPH----GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSS 540 P LP A P G + P P G GA G P P +P Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPL 1036 Query: 541 QG-GSPALFTYNGMTDPGAQPL-FFGVAQPQVSPHGTPSLPPPRVVGAS-PSESPLPS-- 595 G G P G P PL G+ P P G PPP + GA P PLP Sbjct: 1037 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAG 1095 Query: 596 ----PATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLG-PSAFFHPPTHPQETGSPFPS 650 P G P + P P + +P P P A PP G P P Sbjct: 1096 IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155 Query: 651 PEPPHSLPTHYQPEPAKAF--PFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRA 708 P P +P P P P P G+G P P P VG P A Sbjct: 1156 PLPGAGIPPP-PPLPGAGIPPPPPLPGVG----------IPPPPPLPGVGIPPPPPLPGA 1204 Query: 709 --PPPYP 713 PPP P Sbjct: 1205 GIPPPPP 1211 Score = 43.5 bits (101), Expect = 0.004 Identities = 123/488 (25%), Positives = 148/488 (30%), Gaps = 78/488 (15%) Query: 1120 GDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPT 1179 G G P P PG P P P A P GA G P P P +P Sbjct: 972 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGAGIPPPPPLPG 1027 Query: 1180 NTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQ 1239 P P P P A PP PG IP Sbjct: 1028 AGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPL-------PGAGIP-- 1075 Query: 1240 PPPSRHDTGTPKPSGSLANTAPHGSSPTPGVG-----SLLGGPGGTQAPVSHNSKDPPAR 1294 PPP G P P L P PGVG L G P+ PP Sbjct: 1076 PPPPLPGAGIPPPP-PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134 Query: 1295 QPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSE 1354 PG + P P P L AG P P+ G P Sbjct: 1135 LPGAGIPPPPPLPRVGIPPPPPLPG---------AGIPPPP---PLPGAGIPPPPPLPGV 1182 Query: 1355 LFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPG 1414 P L G + P P A PP + A P LP PPGT P Sbjct: 1183 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA----PPLP--PPGTGIPPPP 1236 Query: 1415 R--AASPPTLES--SSLFPDLPVDRFDPP-----LYGSLSANRDSGLPFACADPPQKTVP 1465 + PP L SS P V F PP L+G L N+D G + P + P Sbjct: 1237 LLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFG-LGMNQDKG---SRKQPIEPCRP 1292 Query: 1466 SDPPY------------PSFLLLEEVS-PMLPSH-FPDLSGGKVLSKTCPP-----ERTV 1506 P Y + L+ E++ P + H F +L + + P +T Sbjct: 1293 MKPLYWTRIQLHSKRDSSTSLIWEKIEEPSIDCHEFEELFSKTAVKERKKPISDTISKTK 1352 Query: 1507 VPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQ------LQRSKDTRGAPREL 1560 L K S LMS L D +IQ V L++ LQ + R EL Sbjct: 1353 AKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDEL 1412 Query: 1561 AEAESVGR 1568 + E GR Sbjct: 1413 EKIEKHGR 1420 Score = 43.1 bits (100), Expect = 0.005 Identities = 88/352 (25%), Positives = 123/352 (34%), Gaps = 66/352 (18%) Query: 873 PSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLA 932 PSG G + G P +A ++ S P L A +PQ P P G P P + Sbjct: 256 PSGGAGEAPGSPDTEQA-LSALSDLPESLAAEPREPQQP-PSPGGLPVSEAPSLPAA--Q 311 Query: 933 PTEADAPSQGR----QQRRGKQLKLFRKDLDSGGAAEGSGSG---GGGRASGLRPRRNDG 985 P D+PS + G++ +G G+G G A PR + G Sbjct: 312 PAAKDSPSSTAFPFPEAGPGEEA--------AGAPVRGAGDTDEEGEEDAFEDAPRGSPG 363 Query: 986 ------LGERPPPR-PRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRK 1038 +GE P R P +A G P P AA+LP S+R P Sbjct: 364 EEWAPEVGEDAPQRLGEEPEEEAQG------PDAPAAASLPGSPAPSQRCFKPYP----- 412 Query: 1039 RKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVEL 1098 ++ K R+ +S + Q P + P R ++R E L Sbjct: 413 ------------LITPCYIKTTTRQ--LSSPNHSPSQSPNQSP-------RIKRRPEPSL 451 Query: 1099 TQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAARE 1158 ++G R A + A G A + R+P+ G + LE G A+ Sbjct: 452 SRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDS 511 Query: 1159 GG---PKCADRPSVAP--KDPLQVPTNTETSEETRPSLDFPQEAKEPETAEE 1205 GG P A + S AP D Q N T L QE PE AE+ Sbjct: 512 GGGVSPALAAKASGAPAAADGFQ---NVFTGRTLLEKLFSQQENGPPEEAEK 560 Score = 42.7 bits (99), Expect = 0.007 Identities = 83/315 (26%), Positives = 112/315 (35%), Gaps = 53/315 (16%) Query: 20 PRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLR 79 P +A+ P P QPP P ++A LP AQP A+D Sbjct: 280 PESLAAEPREPQQPPSPGGLPV-------------SEAPSLPAAQP-AAKD--------- 316 Query: 80 GQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPEN 139 +PSST P+ PG AP R AG + + + R P + PE Sbjct: 317 --SPSSTAFP--FPEAGPGEEAAGAPVRGAGDTDEEGEEDAFED--APRGSPGEEWAPEV 370 Query: 140 PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPP------SSFTS 193 + +L E + G AP LP PA + RCF+ P T+ Sbjct: 371 GEDAPQRLGEEPEEEAQGPDAPAAASLP---GSPAPSQ----RCFKPYPLITPCYIKTTT 423 Query: 194 TNYTSPSATP-RPPAPGPPQSRGTSP-LQPGSYPEYQASGADSWPPAAENSFPGANFGVP 251 +SP+ +P + P P R P L GS + A + A+ Sbjct: 424 RQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSA 483 Query: 252 PAEPEPIPKGSRPGGS----PRGVSFQF---PFPALHG-ASTKPFPADVAGHAFTNGPLV 303 E + R GGS RGV+ PAL AS P AD + FT L+ Sbjct: 484 DWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGRTLL 543 Query: 304 -FAFHQPQGAWPEEA 317 F Q + PEEA Sbjct: 544 EKLFSQQENGPPEEA 558 Score = 40.8 bits (94), Expect = 0.027 Identities = 53/213 (24%), Positives = 76/213 (35%), Gaps = 19/213 (8%) Query: 3640 GSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAK 3699 G A + G + + SA S ++L PR+ +PG L + A P AK Sbjct: 258 GGAGEAPGSPDTEQALSALSDLPESLA--AEPREPQQPPSPGGLPVSEAPSLPAAQPAAK 315 Query: 3700 PGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAK 3759 PSS P G P +G E A P SP E P + Sbjct: 316 DSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEE-GEEDAFEDAPRGSPGEEWAPEVGE-- 372 Query: 3760 SCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPG-PARSESVGSFGRAP-SAPDKPP 3817 P+ GE+ P+E+ + +PG PA S+ F P P Sbjct: 373 ---DAPQRLGEE-------PEEEAQGPDAPAAASLPGSPAPSQR--CFKPYPLITPCYIK 420 Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQR 3850 T R+ ++P+ P + + K RP PS R Sbjct: 421 TTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSR 453 Score = 40.8 bits (94), Expect = 0.027 Identities = 104/422 (24%), Positives = 144/422 (34%), Gaps = 67/422 (15%) Query: 1121 DGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTN 1180 DG P P P G+ GP Q + S + R + +P+ + P P+ Sbjct: 761 DGLPGRPPCPPGAESGP----QTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSL 816 Query: 1181 TETSEETRPSLDFPQE-AKEPETAEESAPDSTEFTEALR---SPPAACAGEMGASPGLLI 1236 ++ + +P P + E +T+ E + S F + PP C + PGL + Sbjct: 817 LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSA-FKNSCNIPSPPPLPCTESSSSMPGLGM 875 Query: 1237 PEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQP 1296 PPP P +L +TA P G L P P+ PP P Sbjct: 876 VPPPPPPLPGMTVP----TLPSTAIPQPPPLQGTEMLPPPP----PPLPGAGIPPPPPLP 927 Query: 1297 GEFLAPVAN-PSSTACPKPSVLSSKISSFGCDP-AGFNRDPLGVPVAKKG-PQPYSSPHS 1353 G + P+ P + P P + + I P AG PL P+ G P P P + Sbjct: 928 GAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGI---PLPPPLPGAGIPPPPPLPGA 984 Query: 1354 ELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEP 1413 + P L G + P P A PP P LP + P Sbjct: 985 GI-PPPPPLPGAGIPPPPPLPGAGIPPP-----------------PPLPGAGIPPPPPLP 1026 Query: 1414 GRA-ASPPTLESSSLFPDLPVDRF----DPPLYGSLSANRDSGLPFACADPPQKT----V 1464 G PP L + + P P+ PPL G+ LP A PP + Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGI 1085 Query: 1465 PSDPPYPSFLLLEEVSPMLPS----HFPDLSGGKVLSKTCPPERTVVPGAA----PSLPG 1516 P PP P + P LP P L G + P +PGA P LPG Sbjct: 1086 PPPPPLPGAGI--PPPPPLPGVGIPPPPPLPGAGI------PPPPPLPGAGIPPPPPLPG 1137 Query: 1517 KG 1518 G Sbjct: 1138 AG 1139 Score = 37.0 bits (84), Expect = 0.39 Identities = 60/254 (23%), Positives = 82/254 (32%), Gaps = 60/254 (23%) Query: 413 ASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQ 472 + G +PG PDTE A + L L + AA P P P PSPG Sbjct: 257 SGGAGEAPGSPDTEQAL-----SALSDLPESLAAE-PREPQQP------------PSPGG 298 Query: 473 RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPRE 532 LP S P P A+ SP + PFP GP + G AG T Sbjct: 299 ---LPVSEAPSLPAAQPAAKDSPSS----TAFPFPEAGPGEEAAGAPVRG-AGDT----- 345 Query: 533 KLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESP 592 + G + F + +P G+P VG + Sbjct: 346 ---------------------DEEGEEDAF------EDAPRGSPGEEWAPEVGEDAPQRL 378 Query: 593 LPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPE 652 P G + + + SPA S+ P PL + T + + PS Sbjct: 379 GEEPEEEAQGPDAPAAASLPGSPA--PSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQS 436 Query: 653 PPHSLPTHYQPEPA 666 P S +PEP+ Sbjct: 437 PNQSPRIKRRPEPS 450 Score = 34.3 bits (77), Expect = 2.5 Identities = 30/120 (25%), Positives = 42/120 (35%), Gaps = 12/120 (10%) Query: 567 QPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLP 626 Q Q+ P+ PP V SP P +P +P +E++ Sbjct: 223 QQQLQGAEEPAAPPTAV-------SPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSA 275 Query: 627 GPLGPSAFFHPPTHPQETGSP-----FPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGA 681 P + P PQ+ SP +P P + P + AFPFP G G E A Sbjct: 276 LSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAA 335 Score = 34.3 bits (77), Expect = 2.5 Identities = 134/619 (21%), Positives = 197/619 (31%), Gaps = 122/619 (19%) Query: 2029 SPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPS 2088 +P SP+ E AL+ +E R P++ SPG P+ PA A S Sbjct: 263 APGSPDTEQALSALSDLPESLAAEPREPQQPPSPG-GLPVSEAPSLPAAQ----PAAKDS 317 Query: 2089 PTSAAHMPCSLGPLPREDPLTSPSRAQGGL---GGQLPASPSCRDPPGPQQLLACSPAWA 2145 P+S A GP E+ +P R G G + + R PG + WA Sbjct: 318 PSSTAFPFPEAGP--GEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEE--------WA 367 Query: 2146 PLEEADGVQATTDTGAEDS--PVAPP--SLTTSPCD------PKEALAGCLLQGEGSPLE 2195 P D Q + E++ P AP SL SP P + C ++ L Sbjct: 368 PEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLS 427 Query: 2196 DPSSWPP-------------------------GSVSAVTCTHSGDTPKDSTLRIPEDSRK 2230 P+ P SV+A H D + L D + Sbjct: 428 SPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTE 487 Query: 2231 EKLWESPG---------RATSPPLAGAVSPSVAVRATGLSSTPTG-DEAQAGRGLPGP-- 2278 E +P R + G VSP++A +A+G + G GR L Sbjct: 488 ELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGRTLLEKLF 547 Query: 2279 DPQSRGAP-----------------PHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVP 2321 Q G P P ++ R P + + +N A + AV Sbjct: 548 SQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQN--AQTNAASFDQDQLYTWAAVS 605 Query: 2322 TEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTT 2381 +L + P + MG SK P++ E + + T R+ Sbjct: 606 QPTHSLDYSEGQFPRRVP-SMGPPSKPPDEEHRLEDAETESQSAVSETPQK------RSD 658 Query: 2382 APSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPH 2441 A D +S+ + QT + +L+++ + AS G G Sbjct: 659 AVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTAS 718 Query: 2442 GPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA------------ALPAQQPLE 2489 G +VC + R L + R HR + SP LP + P Sbjct: 719 G----DVCLEALR----LEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCP 770 Query: 2490 PLAQKCQPPRKKSHRVSGKERPNH------SRGDPSHVTQPPPAQGSKEVLRAPGSPHSQ 2543 P A+ P K +S P S ++QPPP S G P SQ Sbjct: 771 PGAES-GPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP-SLLWSAGQGQPGSQ 828 Query: 2544 QLHPPS---PTEHEVDVKT 2559 H S T HE V + Sbjct: 829 PPHSISTEFQTSHEHSVSS 847 Score = 34.3 bits (77), Expect = 2.5 Identities = 37/145 (25%), Positives = 48/145 (33%), Gaps = 18/145 (12%) Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGST--CSSLSPMSSSPANPSSEESQLPGPLGP 631 G +LPP V P P P P + T CS +S + S P QL Sbjct: 753 GVLTLPP---VDGLPGRPPCP-PGAESGPQTKFCSEISLIVS----PRRISVQLDSHQPT 804 Query: 632 SAFFHPPTHPQ---ETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEET 688 + PP P G P +PPHS+ T +Q + + + Sbjct: 805 QSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSV-----SSAFKNSCNIPSPP 859 Query: 689 PFPHEGPEVGRGGLQGFPRAPPPYP 713 P P GL P PPP P Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPPLP 884 Score = 32.3 bits (72), Expect = 9.5 Identities = 28/90 (31%), Positives = 34/90 (37%), Gaps = 6/90 (6%) Query: 3217 AGKAAGSPGDPWGQEGEAKKDSPGE-RAKPRARSTPSNPDGAATPDSASATALADAGSPG 3275 AG+A GSP Q A D P A+PR P +P G ++ S A A Sbjct: 260 AGEAPGSPDTE--QALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDS 317 Query: 3276 PPRTT---PSPSPDPWAGGEPLLQATPVHE 3302 P T P P A G P+ A E Sbjct: 318 PSSTAFPFPEAGPGEEAAGAPVRGAGDTDE 347 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 87.8 bits (216), Expect = 2e-16 Identities = 224/916 (24%), Positives = 308/916 (33%), Gaps = 166/916 (18%) Query: 87 PGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQ 146 PG S Q PG P P+ L A + P I +SR + P P + Sbjct: 1028 PGPELSAQPTPGPVPQVLPASLMVSASPAGPPL----IPASRPPGPVLLPPLQPN--SGS 1081 Query: 147 LPEV-DTPQG--PGTGAPLRPGLPRTEAQPAAEELG---------------FHRCFQEPP 188 LP+V +P G GT P P L PA L + PP Sbjct: 1082 LPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPP 1141 Query: 189 SSFTSTNYTSPSATPRP-PAPGP-PQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGA 246 ++ T+T+ T+ +AT PAP P PQ SP P + A+ A Sbjct: 1142 AAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANA 1201 Query: 247 NFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAF 306 P K + G R ++ P +P +V H + G Sbjct: 1202 GGSKPLTFQIQGNKLTLTGAQVRQLAVGQP---------RPLQRNVV-HLVSAGGQHHLI 1251 Query: 307 HQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLN-------------------- 346 QP +AV P P P PS P P GL+ Sbjct: 1252 SQPAHVALIQAVAPTPG-PTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVK 1310 Query: 347 ---RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTK---ILPERPPSAQDGLGSTRGPPSS 400 R + G P A APRP S L L + P R P+ LG+ R P + Sbjct: 1311 IVVRQAPRDGLTPVPPLA-PAPRPPSSGLPAVLNPRPTLTPGRLPTPT--LGTARAPMPT 1367 Query: 401 -------LPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPG 453 L H P AS +PG +++P P+ LP P ++P P P Sbjct: 1368 PTLVRPLLKLVHSPSPEVSAS----APGAAPLTISSPLHVPSSLP---GPASSPMPIPNS 1420 Query: 454 GPLAATRSMFFNGQPSPGQRLCLPQSAPLPW--PQVLPTARP---SPHGMEMLSRLPFPA 508 PLA+ S + S + +P + P P P +P + P S G +L+ + P Sbjct: 1421 SPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPL 1480 Query: 509 GGPEWQGGSQGALGTAGKTPGPRE------KLPAVRSSQG-GSPALFTYNGMTDPGAQPL 561 +L +G +P P++ SSQ G P L PG Sbjct: 1481 APVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNST 1540 Query: 562 FFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSS-------- 613 P + P + P P +P+++ L +PA++ + + + L+PM++ Sbjct: 1541 VAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAP 1600 Query: 614 SPANPSS---------------EESQLPGP-LGPSAFFHPPTHPQETGSPFPSPEP---P 654 SPA P + SQ P P + PS+ P + SP P+P P P Sbjct: 1601 SPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSS---TPGTSLASASPVPAPTPVLAP 1657 Query: 655 HSLPTHYQPEPAKAFPFPA--DGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPY 712 S T P PA L A P + +G G QG P+ Sbjct: 1658 SSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQG------PF 1711 Query: 713 PTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPG 772 PT SL+ A SSL A Q L Q P Sbjct: 1712 PTQTLSLTPA------------------SSLVPTPA--QTLSLAPGPPLGPTQTLSLAPA 1751 Query: 773 LPSPPAAPRVPADAHAGLLSHAKT--FLLAGDAQAEGKDDPLRTGFL-PSLAATPFPLPA 829 P PA+P PA AH L+ A + LLA + P L P+ A T PA Sbjct: 1752 PPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPA 1811 Query: 830 SDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEP-----SGPRGPSSGHP 884 S A SL+ A + P S + V DE SGP P S Sbjct: 1812 STQSPASQA--SSLVVSASGA----APLPVTMVSRLPVSKDEPDTLTLRSGPPSPPS--T 1863 Query: 885 LKSKAGVTPESKAPPP 900 S G P + PPP Sbjct: 1864 ATSFGGPRPRRQPPPP 1879 Score = 84.7 bits (208), Expect = 2e-15 Identities = 196/804 (24%), Positives = 264/804 (32%), Gaps = 153/804 (19%) Query: 9 APPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQA 68 APPP + L+P V PP PA TT A A+ P P++ Sbjct: 1119 APPPGSSSLLKPLTV---------PPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRL 1169 Query: 69 RDGELKPPSLRGQAPSS---TPGKRGSPQTPP-----GRSPLQ------------APSRL 108 + P ++ + PS + G+ S P G PL A R Sbjct: 1170 ----ILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQ 1225 Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168 + P QR ++ + S+ + L P + L A P TP GP + L P Sbjct: 1226 LAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAP---TP-GPTPVSVLPSSTPS 1281 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTS---------------PSA-TPRPPAPGPPQ 212 T P L Q PP+ +T P A PRPP+ G P Sbjct: 1282 TTPAPTGLSLPL-AANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPA 1340 Query: 213 SRGTSP-LQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGV 271 P L PG P A + P P P P S PG +P + Sbjct: 1341 VLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKL---VHSPSPEVSASAPGAAPLTI 1397 Query: 272 SFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPA 331 S LH S+ P PA + P+ P + V + LP Sbjct: 1398 S-----SPLHVPSSLPGPA--------SSPMPIPNSSPLASPVSSTVSVPLSSSLPIS-V 1443 Query: 332 PSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGL 391 P+ LP P + + L+ + S P S P L ++P P Sbjct: 1444 PTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPP--------LAPVVPAAP------- 1488 Query: 392 GSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP------------------ 433 GPPS P P + G+ T+P ++ PG P Sbjct: 1489 ----GPPSLAPSGASPSASALTLGLATAPSLSSSQ--TPGHPLLLAPTSSHVPGLNSTVA 1542 Query: 434 PARLPQLWDPTA-------APYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSA---PLP 483 PA P L +A AP P P L A S +P + PQ+A P P Sbjct: 1543 PACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSP 1602 Query: 484 WPQV--LPTARPSPHGMEML--SRLPFPAGGPEWQGGSQGALGTAGKTPGP--------- 530 P + LP PSP +L S+ P P P G+ +L +A P P Sbjct: 1603 APPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGT--SLASASPVPAPTPVLAPSST 1660 Query: 531 REKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGT--PSLP-PPRVVGAS 587 + LPA S SPA T P P G + Q GT P P P + + + Sbjct: 1661 QTMLPAPVPSPLPSPAS-TQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLT 1719 Query: 588 PSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPG-PLGPSAFFHPPTHPQETGS 646 P+ S +P+PA +LS P P+ S P PL P++ P T + Sbjct: 1720 PASSLVPTPA--------QTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLA 1771 Query: 647 PFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFP 706 P S SL + P P LG A Q L P + P L Sbjct: 1772 PASSSA---SLLAPASVQTLTLSPAPVPTLGPAAA-QTLALAPASTQSPASQASSLVVSA 1827 Query: 707 RAPPPYPTHHFSLSSASLDQLDVL 730 P P S S D+ D L Sbjct: 1828 SGAAPLPVTMVSRLPVSKDEPDTL 1851 Score = 66.2 bits (160), Expect = 6e-10 Identities = 135/540 (25%), Positives = 171/540 (31%), Gaps = 102/540 (18%) Query: 83 PSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQL 142 PSS PG SP P SPL +P + S P L I+ T P P + Sbjct: 1404 PSSLPGPASSPMPIPNSSPLASPV----SSTVSVPLSSSLPISVPTTLPAPASAPLTIPI 1459 Query: 143 EA---------AQLPEVDTPQGPGT-GAPLRPGLPRTEAQPAAEELGF------------ 180 A A L V P P AP P L + A P+A L Sbjct: 1460 SAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQ 1519 Query: 181 ---HRCFQEPPSSFT-STNYT------------SPSATPRPPAPGPPQSRGTSPLQPGSY 224 H P SS N T S A+P P AP P ++ S L P S Sbjct: 1520 TPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQ-ASLLAPASS 1578 Query: 225 PEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGAS 284 QA P AA + A PP P P+ S PG +P S Q P P + Sbjct: 1579 AS-QALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPS-PGAAPVLASSQTPVPVM---- 1632 Query: 285 TKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGG 344 P+ G + + V A P + + P PSPLP Sbjct: 1633 ---APSSTPGTSLASASPVPA--------PTPVLAPSSTQTMLPAPVPSPLP-------- 1673 Query: 345 LNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQR 404 SP + + +L +L L PS LG+ PQ Sbjct: 1674 ------------SPASTQTL------ALAPALAPTLGGSSPSQTLSLGTGN------PQG 1709 Query: 405 HFPGQAYRASGVDT-SPGPPDTELAAPGPPPARLPQLWDPTAAPY-PTPPGGPLAATRSM 462 FP Q + + P P T APGPP L A P P P GP A Sbjct: 1710 PFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLT 1769 Query: 463 FFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALG 522 S L P S P P + L+ P P Q S + Sbjct: 1770 L--APASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSL-VVS 1826 Query: 523 TAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPR 582 +G P P + + S+ L +G P + FG +P+ P PPPR Sbjct: 1827 ASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPP-----PPPR 1881 Score = 65.1 bits (157), Expect = 1e-09 Identities = 204/872 (23%), Positives = 287/872 (32%), Gaps = 162/872 (18%) Query: 1831 PAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQD--PALSPPIRQLQLPGPGVAKSK 1888 P G+SSL P P+ A ++T + + PA +P ++L L A+ Sbjct: 1121 PPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLP 1180 Query: 1889 DG-ILGLQELTPAAQSPPRVNPSGLEGGT--VEGGKVACGPAQ------GSPGGVQ--VT 1937 G ++ + +L AQ P N G + T ++G K+ AQ G P +Q V Sbjct: 1181 SGEVVSIGQLASLAQRPV-ANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVV 1239 Query: 1938 TLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQ---PENGVSPGGTDNHASVNASP 1994 L + G + H L+ T G + L P +P G + N P Sbjct: 1240 HLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVP 1299 Query: 1995 KTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGR 2054 T + G V + + R ++ P P PPS ++ Sbjct: 1300 PTMVNNT--GVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAV---------------- 1341 Query: 2055 TPERASSPGLN-KPLLATGDSPAPSVGDLAACAPSPT----------------------- 2090 LN +P L G P P++G A P+PT Sbjct: 1342 ---------LNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGA 1392 Query: 2091 ------SAAHMPCSLG-------PLPREDPLTSP--SRAQGGLGGQLPASPSCRDPPGPQ 2135 S H+P SL P+P PL SP S L LP S P P Sbjct: 1393 APLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVP-TTLPAPA 1451 Query: 2136 QLLACSPAWAPLE-EADGVQATTDTGAEDSPV-----APPSLTTSPCDPKEALAGCLLQG 2189 P APL A G T +PV PPSL S P A L G Sbjct: 1452 SAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPS---ASALTLG 1508 Query: 2190 EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV 2249 + SS PG + T S +ST+ P S P A + P A Sbjct: 1509 LATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTV-APACSPV----LVPASALASPFPSAP 1563 Query: 2250 SPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARL 2309 +P+ A +A+ L+ + +A A P PQ+ P P P + SP L Sbjct: 1564 NPAPA-QASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVL 1622 Query: 2310 GHREGQAVTAVPTEPP--TLQGAGP-DSPACLEGEMGTSSKEPEDPGTPETGRSGATKMP 2366 + P+ P +L A P +P + T + P +P +P Sbjct: 1623 ASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSP---------LP 1673 Query: 2367 RVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKK 2426 T L L AP+ S SP + PQG P Q L Sbjct: 1674 SPASTQT-LALAPALAPTLGGS-----SPSQTLSLGTGNPQG-PFPTQTL-------SLT 1719 Query: 2427 PAST---ENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP 2483 PAS+ Q AP GP S P L+ P +P P+PA Sbjct: 1720 PASSLVPTPAQTLSLAP-GPPLGPTQTLSLAPAPPLA----------PASPVGPAPAHTL 1768 Query: 2484 AQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHV------TQPPPAQGSKEVLRAP 2537 P A P ++ +S P + TQ P +Q S V+ A Sbjct: 1769 TLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSAS 1828 Query: 2538 GSPHSQQLHPPSPTEHEVDVKTPASKPRPDQ---AREDELHPKQAEKREGRRWRREPTVD 2594 G+ +P + + P SK PD P A G R RR+P Sbjct: 1829 GA---------APLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPP 1879 Query: 2595 --SPSHSEGKSNKKRGKLRGRRLREESILPVS 2624 SP + + K++ R R R E I +S Sbjct: 1880 PRSPFYLDSLEEKRK---RQRSERLERIFQLS 1908 Score = 54.3 bits (129), Expect = 2e-06 Identities = 197/911 (21%), Positives = 293/911 (32%), Gaps = 143/911 (15%) Query: 340 GQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLH--KSLTKILPERPPSAQDGLGSTRGP 397 G GG +R S + A PG S+ L ++ T+ P + ST P Sbjct: 2373 GTGGGTHRRSKKAKAPERPGTR------VSERLRGARAETQGANHTPVISAHQTRSTTTP 2426 Query: 398 PSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLA 457 P P R + +P P T +AP PA +P P +AP P P+ Sbjct: 2427 PRCSPARERVPRP--------APRPRPTPASAPAAIPALVPV---PVSAPVPISAPNPIT 2475 Query: 458 ATRSMFFNGQPSPGQ------RLCLPQSAPLPWPQVLP----TARPSPHGMEMLS--RLP 505 P P Q C P A P P P T +P +L +P Sbjct: 2476 ILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVP 2535 Query: 506 FPAGGPEWQGGSQGALGTAGKTPGPRE--KLPAVRSSQGGSPALFTYNGMTDPGAQPLFF 563 A G + + E +L +V SS+ S +L + + L Sbjct: 2536 ISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEIL-- 2593 Query: 564 GVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623 V++ +S TPS P + S + G+T + L P S Sbjct: 2594 PVSEKNLSL--TPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNG 2651 Query: 624 -QLPGPLGPSAFFHPPTHPQETG-------SPFPSPEPPHSLPTHYQPEPAKAFPFPADG 675 +LP P T +P SPE P L T P+ + + Sbjct: 2652 LELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSP 2711 Query: 676 LGAEGAFQCLEETPFPHE--GPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTC 733 G A T E G GR G P+ P ++ +++ +++ Sbjct: 2712 EGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTV----VEEKELVRRR 2767 Query: 734 RQCDRNYSSLAAFLAHRQFC-GLLLARAKDGHQRSP---GP------PGLPSPPAAPRVP 783 RQ S+L ++ G R+ G + SP GP LP+PP P + Sbjct: 2768 RQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFI- 2826 Query: 784 ADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAK-LDS 842 A H L + G E D L P++ P + D + +D Sbjct: 2827 ARRHIELG-------VTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDE 2879 Query: 843 LITEALNGMEYQSDNPEIDSSFI--------DVFADEEPSGPRGPSSGHPL-----KSKA 889 + L G +D + I + +P GP+ +PL K + Sbjct: 2880 APSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRR 2939 Query: 890 GVTPESKAPP----------------PLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAP 933 G P+++ P P P P TP P CP T + Sbjct: 2940 GRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTIS 2999 Query: 934 TEADAPSQGRQQR-----RGKQLKLFRKD----LDSGGAAEGSGSGGGGRASGLRPRRND 984 T +GR + R QL + +D L+S G G G + G +D Sbjct: 3000 TSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEG---SSSD 3056 Query: 985 GLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGG 1044 G RP R R R +A G R + A + ++ A G Sbjct: 3057 EDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDL----------------ADSG 3100 Query: 1045 AWGKELILKIVQ-----QKNRLREYDFASESEEDEQPPPR-GPGFRGRRGRGEK-RKEVE 1097 G EL +V + RLR E ++ P R G G G ++ R + Sbjct: 3101 PGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPP 3160 Query: 1098 LTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGR--SPQARGPSRSLETGAA 1155 GP + +A+ +E GDG P RPGP R +G R L + A Sbjct: 3161 SPLGPEGSVEESEAEASGEEEEGDGTPRR-------RPGPRRLVGTTNQGDQRILRSSAP 3213 Query: 1156 AREGGPKCADR 1166 GP + R Sbjct: 3214 PSLAGPAVSHR 3224 Score = 53.1 bits (126), Expect = 5e-06 Identities = 111/423 (26%), Positives = 138/423 (32%), Gaps = 54/423 (12%) Query: 3451 MPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPI 3510 +P S PGP P SSP+ S S + L S + S P TL P Sbjct: 1403 VPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISV----PTTLPAPAS------ 1452 Query: 3511 RGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLG 3570 P P A L AL ++ P P +PGP P G Sbjct: 1453 -------------APLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGP--PSLAPSG 1497 Query: 3571 ASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSE 3630 AS P A AP + S + PG AP L S +V Sbjct: 1498 AS---PSASALTLGLATAPSLSSS--QTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPA 1552 Query: 3631 GGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKA--VGSLAPGELARGTE 3688 F SA PA Q+S + AS+ S+AL P+ P A LAP Sbjct: 1553 SALASPF--PSAPNPAPAQASL--LAPASSASQALATPLAPMAAPQTAILAPSPAPPLAP 1608 Query: 3689 NGMKPATPKAKPGPSSQGSGSP------RPGTKTGGGSQ-PQPASGQLQSETAT-TPAKP 3740 + +P A P +S + P PGT S P P S T T PA Sbjct: 1609 LPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPV 1668 Query: 3741 SFPSRSPAPERLPARAQAKSCTKG---PREAGEQGPHGSLGPKEKGESSTKRKKGQVPGP 3797 P SPA + A A A + T G P + G GP S VP P Sbjct: 1669 PSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTP 1728 Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATP--SRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855 A++ S+ AP P P +T P + P P P P S P Sbjct: 1729 AQTLSL-----APGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPA 1783 Query: 3856 HTQ 3858 Q Sbjct: 1784 SVQ 1786 Score = 49.3 bits (116), Expect = 8e-05 Identities = 158/656 (24%), Positives = 211/656 (32%), Gaps = 141/656 (21%) Query: 4 ERPRGAPPPTMT----GDLQPRQVASS------PGHPSQPPLEDNTPATRTTKGAREAGG 53 E P A T+T G+ P V+ S P S PL++ A RT++ EA Sbjct: 2623 EAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKT 2682 Query: 54 QAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGR---SPLQAPSRLAG 110 + E +P++ E+ PS A SS G SP PP R + ++ + G Sbjct: 2683 PTSSPE----KPQELVTAEVAAPSTSSSATSSPEGP--SPARPPRRRTSADVEIRGQGTG 2736 Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTE 170 R G PP +L R ++E + Q G + L PG+ T Sbjct: 2737 RP-GQPPGPKVLRKLPGRLVTVVEEKELVRRRR----------QQRGAASTLVPGVSETS 2785 Query: 171 AQPAAEELGFHRCFQEPPSSFTSTNYTSP-SATPRPPAPGPPQSRGTSPLQPGSYPEYQA 229 A P + + R P SS P A P P PPQ P + E Sbjct: 2786 ASPGSPSV---RSMSGPESS---PPIGGPCEAAPSSSLPTPPQQ----PFIARRHIELGV 2835 Query: 230 SGADSWPPAAENSFPGANFGVPPA----EPEPIPKGSRPGGSPRGVSFQFPFPALHGAST 285 +G S EN PPA P K P + RGV + P L G + Sbjct: 2836 TGGGS----PENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVD-EAPSSTLKGKTN 2890 Query: 286 KPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPL---PCYQGQP 342 P V G PE + P P P PL P ++ P Sbjct: 2891 GADP--VPG-------------------PETLIVADPVLEPQLIPGPQPLGPQPVHRPNP 2929 Query: 343 GGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLP 402 L SP RP K+ +P SA DG +R P Sbjct: 2930 ------------LLSPVEKRRRGRP-----PKARDLPIPGTISSAGDGNSESRTQP---- 2968 Query: 403 QRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSM 462 PP P PP L PTA T ++ + Sbjct: 2969 -------------------PPHPSPLTPLPP-----LLVCPTATVANTVTTVTISTSPPK 3004 Query: 463 FFNGQPSPGQRLCLPQSAPLPWPQVLPTA-RPSPHGMEM--LSRLPFPAGGPEWQGGSQG 519 G+P P++ P P P LP R S +E L R P G E +G S Sbjct: 3005 RKRGRP--------PKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSD 3056 Query: 520 ALGTAGKTPGPREKLPAV----RSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGT 575 G+ T R +L A R S G + + + P + P VS T Sbjct: 3057 EDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSL--T 3114 Query: 576 PSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGP 631 P L R+ S L P + +P+ SP Q P PLGP Sbjct: 3115 PKLRSTRLRPGS-----LVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGP 3165 Score = 48.9 bits (115), Expect = 1e-04 Identities = 161/698 (23%), Positives = 216/698 (30%), Gaps = 119/698 (17%) Query: 300 GPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPG 359 G V + P+ V P L QP P P+P Q P L + +G P Sbjct: 1006 GRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVP--QVLPASLMVSASPAGPPLIP- 1062 Query: 360 AAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTS 419 A P P + + LP+ PS L T PP+ + Sbjct: 1063 -ASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPT--------------LSLK 1107 Query: 420 PGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQS 479 P PP +P PPP L T P T P P AAT + + + +P Sbjct: 1108 PTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFP--PAAATTT---STTTATATTTAVPAP 1162 Query: 480 APLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRS 539 P P +L SP +M +RL P + S G L + + P V + Sbjct: 1163 TPAPQRLIL-----SP---DMQARL------PSGEVVSIGQLASLAQRP--------VAN 1200 Query: 540 SQGGSPALFTYNG--MTDPGAQPLFFGVAQPQ---------VSPHGTPSL---------- 578 + G P F G +T GAQ V QP+ VS G L Sbjct: 1201 AGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALI 1260 Query: 579 ------PPPRVVGASPSESPLPSPA-----------------TNTAG--------STCSS 607 P P V PS +P +PA N G + Sbjct: 1261 QAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDG 1320 Query: 608 LSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAK 667 L+P+ P S LP L P P P T +P P PT +P Sbjct: 1321 LTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMP---TPTLVRPLLKL 1377 Query: 668 AF-PFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHH---FSLSSAS 723 P P A GA P P L G +P P P +SS Sbjct: 1378 VHSPSPEVSASAPGA------APLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTV 1431 Query: 724 LDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVP 783 L L + +A L L ++ + S PP P PAAP P Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP 1491 Query: 784 ADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSL 843 + A +G S + + L G A A G LA T +P + + + Sbjct: 1492 SLAPSG-ASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLV 1550 Query: 844 ITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPA 903 AL + NP + + P+ + PL A AP P P Sbjct: 1551 PASALASPFPSAPNPAPAQASL-----LAPASSASQALATPLAPMAAPQTAILAPSPAPP 1605 Query: 904 ATPDP-QTPRPGDRGCPARGRPKTRSLGLAPTEADAPS 940 P P P PG P +T +AP+ S Sbjct: 1606 LAPLPVLAPSPG--AAPVLASSQTPVPVMAPSSTPGTS 1641 Score = 48.1 bits (113), Expect = 2e-04 Identities = 97/423 (22%), Positives = 145/423 (34%), Gaps = 62/423 (14%) Query: 1089 RGEKRKEVELTQGPREDEPQKPRKAAR-----QEAGGDGAPANPEEPGGSRPGPGRSPQA 1143 R E ++ E + R+D Q + R +E G G ++ GG+ RS +A Sbjct: 2329 REELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHR---RSKKA 2385 Query: 1144 RGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLD-FPQEAKEPET 1202 + P R + G + P +T T P+ + P+ A P Sbjct: 2386 KAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRP 2445 Query: 1203 AEESAPDSTE--FTEALRSP-PAACAGEMGASPGLLIPEQPPPSR-HDTGTPKPSGSLAN 1258 SAP + + +P P + + P ++P PPPS+ +P + A Sbjct: 2446 TPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPAC 2505 Query: 1259 TAPHGSSP--------TPGVGSLLGGPGGTQAPVSHNSKDPP-ARQPGEFLAPVANPSST 1309 T P +P TP LLG P P+S + + P +P L A S Sbjct: 2506 TPPPAHTPPPAQTCLVTPSSPLLLGPPS---VPISASVTNLPLGLRPEAELCAQALASPE 2562 Query: 1310 ACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEE 1369 + SV SS+ SS P PKDL +E Sbjct: 2563 SLELASVASSETSSLSLVP------------------------------PKDLLPVAVEI 2592 Query: 1370 LHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFP 1429 L P++ S + G E + P S GT T P S S Sbjct: 2593 LPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGL 2652 Query: 1430 DLPVD-RFDPPLYGSLSANR------DSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPM 1482 +LP D PL L A+R ++ P + + PQ+ V ++ PS SP Sbjct: 2653 ELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPE 2712 Query: 1483 LPS 1485 PS Sbjct: 2713 GPS 2715 Score = 44.3 bits (103), Expect = 0.002 Identities = 148/698 (21%), Positives = 213/698 (30%), Gaps = 125/698 (17%) Query: 1896 ELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHW 1955 E+ P ++ + PS T+E G + G Q +P + TTL + Sbjct: 2591 EILPVSEKNLSLTPSA-PSLTLEAGSIPNGQEQEAPDSAEGTTLTVL------------- 2636 Query: 1956 GLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSR 2015 PE P + P A P L E + R Sbjct: 2637 -------------------PEGEELPLCVSESNGLELPPSAASDEP-----LQEPLEADR 2672 Query: 2016 AAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSP 2075 + L E PT SP P + L A AA S S S +PE SP + D Sbjct: 2673 TSEELTEAKTPTSSPEKP--QELVTAEVAAPSTSSSATSSPE-GPSPARPPRRRTSADVE 2729 Query: 2076 APSVG-DLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQL----------PA 2124 G P P +P L + E L R Q G L P Sbjct: 2730 IRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPG 2789 Query: 2125 SPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAG 2184 SPS R GP+ + P P E A SL T P P A Sbjct: 2790 SPSVRSMSGPE---SSPPIGGPCEAAPS----------------SSLPTPPQQPFIARRH 2830 Query: 2185 CLL--QGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATS 2242 L G GSP +GD + L I + K + P + S Sbjct: 2831 IELGVTGGGSP------------------ENGD---GALLAITPPAVKRRRGRPPKKNRS 2869 Query: 2243 PPLAGA---VSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHS 2299 P AG +PS ++ + P P +PQ P P + R + Sbjct: 2870 PADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNP 2929 Query: 2300 SYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGR 2359 SP R G + P T+ AG +G + ++ P P +P T Sbjct: 2930 LLSPVEKRRRGRPPKARDLPI---PGTISSAG-------DGNSESRTQPPPHP-SPLTPL 2978 Query: 2360 SGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQR 2419 P T +T + +T+P +P S R + Q P D L+ Sbjct: 2979 PPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPS--QLPVLDRDSTSVLESC 3036 Query: 2420 SRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAP----- 2474 G +++P + G A G+ K+ Sbjct: 3037 GLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDL 3096 Query: 2475 AEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVL 2534 A+ P L P+ L P+ +S R+ RP S P + P + V Sbjct: 3097 ADSGPGGLELTPPVVSLT-----PKLRSTRL----RPG-SLVPPLETEKLPRKRAGAPVG 3146 Query: 2535 RAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQARED 2572 +PG +L PPSP E V+ ++ ++ D Sbjct: 3147 GSPGLAKRGRLQPPSPLGPEGSVEESEAEASGEEEEGD 3184 Score = 41.2 bits (95), Expect = 0.020 Identities = 100/416 (24%), Positives = 139/416 (33%), Gaps = 80/416 (19%) Query: 1135 PGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFP 1194 P PG +P + PS + T A P P A + P + NT + Sbjct: 1265 PTPGPTPVSVLPSSTPSTTPA-----PTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRD 1319 Query: 1195 QEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRH--------- 1245 P A P S+ L P G + +P L P P+ Sbjct: 1320 GLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRL-PTPTLGTARAPMPTPTLVRPLLKLV 1378 Query: 1246 DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVAN 1305 + +P+ S S AP S V S L GP + P+ ++S P+A+ Sbjct: 1379 HSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSS-------------PLAS 1425 Query: 1306 PSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQ------PYSSPHSELFLGP 1359 P S+ P LSS + P+ VP P P S+P + GP Sbjct: 1426 PVSSTVSVP--LSSSL-------------PISVPTTLPAPASAPLTIPISAPLTVSASGP 1470 Query: 1360 KDLAGCFLEELHPKPSARDAPPA--------SSSCLCQDGEDAGSL-EPQLPRSPPGTAE 1410 L L P A PP+ S+S L A SL Q P P A Sbjct: 1471 A-LLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAP 1529 Query: 1411 TE---PG------RAASPPTLESSSLFPDLPVDRFDPPLYGSL-----SANRDSGLPFAC 1456 T PG A SP + +S+L P P SL SA++ P A Sbjct: 1530 TSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589 Query: 1457 ADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAP 1512 PQ + + P P ++P LP P VL+ + P + P + P Sbjct: 1590 MAAPQTAILAPSPAP------PLAP-LPVLAPSPGAAPVLASSQTPVPVMAPSSTP 1638 Score = 38.9 bits (89), Expect = 0.10 Identities = 79/327 (24%), Positives = 108/327 (33%), Gaps = 50/327 (15%) Query: 2524 PPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKRE 2583 P PAQ S L AP S SQ L P A P P A L P Sbjct: 1565 PAPAQAS---LLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPV 1621 Query: 2584 GRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPA---- 2639 + V +PS + G S L S +P V++ PA Sbjct: 1622 LASSQTPVPVMAPSSTPGTS-----------LASASPVPAPTPVLAPSSTQTMLPAPVPS 1670 Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698 + S A++ + L+ P G P + +LG G +G T +L + P Sbjct: 1671 PLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQ 1730 Query: 2699 DRMLCPGRMDG--AALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSR 2756 L PG G L P ++ P T L S S A S + + Sbjct: 1731 TLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTL 1790 Query: 2757 SEEGVWEENTPPLGPLG------FPETSSSPADSTTS-------------SCLQGLP--- 2794 S V P LGP P ++ SPA +S + + LP Sbjct: 1791 SPAPV-----PTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSK 1845 Query: 2795 DNPDTQGGVQGPEGPTPDASGSSAKDP 2821 D PDT GP P+P ++ +S P Sbjct: 1846 DEPDTLTLRSGP--PSPPSTATSFGGP 1870 Score = 35.4 bits (80), Expect = 1.1 Identities = 99/398 (24%), Positives = 129/398 (32%), Gaps = 67/398 (16%) Query: 1123 APANPEEPGGSRPGP-GRSPQARGPSRSLETGAAAREG---------GPKCADRP----S 1168 AP P PG P G SP A + L T + P + P + Sbjct: 1481 APVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNST 1540 Query: 1169 VAPK-DPLQVPTNTETSE--------ETRPSLDFPQEAKEPETAEESAPDSTEFTEALRS 1219 VAP P+ VP + S + SL P + A AP + T L Sbjct: 1541 VAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAP 1600 Query: 1220 PPA-------ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272 PA A GA+P L + P P + TP S + A+ P +PTP + Sbjct: 1601 SPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVP---APTPVL-- 1655 Query: 1273 LLGGPGGTQ----APVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLS---------S 1319 P TQ APV P + Q LAP P+ LS Sbjct: 1656 ---APSSTQTMLPAPVPSPLPSPASTQT-LALAPALAPTLGGSSPSQTLSLGTGNPQGPF 1711 Query: 1320 KISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGP-KDLAGCFLEELHPKPSARD 1378 + PA + P P P P L L P LA P + Sbjct: 1712 PTQTLSLTPAS-SLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTL 1770 Query: 1379 APPASS-SCLCQDGEDAGSLEP-QLPRSPPGTAET---EPGRAASPPTLESSSLFPDLPV 1433 AP +SS S L +L P +P P A+T P SP + SS + Sbjct: 1771 APASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGA 1830 Query: 1434 DRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYP 1471 L S LP + +P T+ S PP P Sbjct: 1831 --------APLPVTMVSRLPVSKDEPDTLTLRSGPPSP 1860 Score = 35.4 bits (80), Expect = 1.1 Identities = 56/256 (21%), Positives = 82/256 (32%), Gaps = 47/256 (18%) Query: 1100 QGPREDEPQKPRKAARQEAGGDGA--PANPEEPGGSRPGPG-------------RSPQAR 1144 +GP P + R +A E G G P P P R PG R Q R Sbjct: 2712 EGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQR 2771 Query: 1145 GPSRSLETG---AAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPE 1201 G + +L G +A G P P+ P E PS P ++P Sbjct: 2772 GAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPC------EAAPSSSLPTPPQQPF 2825 Query: 1202 TAEE---------SAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKP 1252 A +P++ + +PPA G P + P+ G + Sbjct: 2826 IARRHIELGVTGGGSPENGDGALLAITPPAV-KRRRGRPP----KKNRSPADAGRGVDEA 2880 Query: 1253 SGSLANTAPHGSSPTPGVGSLLGGPGGTQ---APVSHNSKDPPARQPGEFLAPVAN---- 1305 S +G+ P PG +L+ + P P +P L+PV Sbjct: 2881 PSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRG 2940 Query: 1306 --PSSTACPKPSVLSS 1319 P + P P +SS Sbjct: 2941 RPPKARDLPIPGTISS 2956 Score = 35.0 bits (79), Expect = 1.5 Identities = 93/378 (24%), Positives = 136/378 (35%), Gaps = 68/378 (17%) Query: 1167 PSVAPKDPLQVPTNTE-TSEE---TRPSLDFPQEAKEPETAEESAPD-STEFTEALRSPP 1221 PS A +PLQ P + TSEE + P++ +E TAE +AP S+ T + P Sbjct: 2656 PSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPS 2715 Query: 1222 AACAGEMGASPGLLI-------PEQPP--------PSRHDTGTPKPSGSLANTAPHGSSP 1266 A S + I P QPP P R T + G++ Sbjct: 2716 PARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAAS 2775 Query: 1267 T--PGVGSLLGGPGGTQA-PVSHNSKDPPARQPGEFLAPVANPSST--ACPKPSVLSSKI 1321 T PGV PG +S PP P E A PSS+ P+ ++ + Sbjct: 2776 TLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCE-----AAPSSSLPTPPQQPFIARRH 2830 Query: 1322 SSFGCDPAGFNRDPLGVPVA--------KKGPQPYSSPHSELFLGPKDLAGCFLEE---- 1369 G G + G +A ++G P + P D AG ++E Sbjct: 2831 IELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKN------RSPAD-AGRGVDEAPSS 2883 Query: 1370 -LHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLF 1428 L K + D P + + D LEPQL P +P +P Sbjct: 2884 TLKGKTNGADPVPGPETLIVAD----PVLEPQLIPGPQPLG-PQPVHRPNPLLSPVEKRR 2938 Query: 1429 PDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPML--PSH 1486 P D P+ G++S+ D + +T P PP+PS L + P+L P+ Sbjct: 2939 RGRPPKARDLPIPGTISSAGD-------GNSESRTQP--PPHPS--PLTPLPPLLVCPTA 2987 Query: 1487 FPDLSGGKVLSKTCPPER 1504 + V T PP+R Sbjct: 2988 TVANTVTTVTISTSPPKR 3005 Score = 34.7 bits (78), Expect = 1.9 Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 2/116 (1%) Query: 932 APTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGS--GSGGGGRASGLRPRRNDGLGER 989 A + +A + Q + + +L +++ + GA + S G+GGG + + + G R Sbjct: 2335 AEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTR 2394 Query: 990 PPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGA 1045 R R R + G+ P + + R S R PR PR R A Sbjct: 2395 VSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASA 2450 Score = 34.7 bits (78), Expect = 1.9 Identities = 152/717 (21%), Positives = 227/717 (31%), Gaps = 109/717 (15%) Query: 2016 AAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSP 2075 A L + E P E ++ G R ++A +P +P + Sbjct: 2342 ARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAP--ERPGTRVSERL 2399 Query: 2076 APSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQ 2135 + + +P +AH S PR SP+R + P+ R P P Sbjct: 2400 RGARAETQGANHTPVISAHQTRSTTTPPR----CSPARER-------VPRPAPRPRPTPA 2448 Query: 2136 QLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLE 2195 A PA P+ PV+ P ++P +P L +L P + Sbjct: 2449 SAPAAIPALVPV-----------------PVSAPVPISAP-NPITILPVHILPSPPPPSQ 2490 Query: 2196 DPSSWPPGSVSAVTCTHS-GDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVA 2254 P P CT TP + + S SP L G S ++ Sbjct: 2491 IPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPS-------------SPLLLGPPSVPIS 2537 Query: 2255 VRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREG 2314 T L + + L P+ + + + S P + + Sbjct: 2538 ASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSL----SLVPPKDLLPV----- 2588 Query: 2315 QAVTAVPTEPPTLQGAGPDSPAC-LEGEMGTSSKEPEDP----GTPETGRSGATKMPRVT 2369 AV +P L P +P+ LE + +E E P GT T ++P Sbjct: 2589 -AVEILPVSEKNLS-LTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCV 2646 Query: 2370 CPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQ-----TPQGDPLGPQDLKQRSRGYK 2424 S GL L P S ASD P S + TP P PQ+L Sbjct: 2647 SESNGLEL-----PPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAP 2701 Query: 2425 KKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSP-AALP 2483 +S + +G +P P A G G R PG P P LP Sbjct: 2702 STSSSATSSP-EGPSPARPPRRRTSADVEIRGQGTGR---------PGQPPGPKVLRKLP 2751 Query: 2484 AQ-----QPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPS--HVTQP---PPAQGSKEV 2533 + + E + ++ Q S V G + S G PS ++ P PP G E Sbjct: 2752 GRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEA 2811 Query: 2534 LRAPGSPHSQQLHPPSPTEHEVDV-KTPASKPRPDQAREDELHPKQAEKREGR--RWRRE 2590 AP S P +++ T P + P ++R GR + R Sbjct: 2812 --APSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRS 2869 Query: 2591 PTVDSPSHSEGKSNKKRGKLRGR-RLREESILPVSADVISDGRGSRPSPAMASYAASPSH 2649 P E S+ +GK G + L V+ V+ P P P+ Sbjct: 2870 PADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNP 2929 Query: 2650 CLS-VEGGPEADGEQPPRLATLG-PGVMEGAAETDQEALCAGETGAQKPPGDRMLCP 2704 LS VE + +PP+ L PG + A + + E+ Q PP L P Sbjct: 2930 LLSPVE---KRRRGRPPKARDLPIPGTISSAGDGN------SESRTQPPPHPSPLTP 2977 Score = 33.1 bits (74), Expect = 5.6 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 1/60 (1%) Query: 3693 PATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL 3752 PA + P P S +P T G + P PA+ S T T + P+ +PAP+RL Sbjct: 1111 PAPVRLSPAPPPGSSSLLKPLTVPPGYTFP-PAAATTTSTTTATATTTAVPAPTPAPQRL 1169 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 86.3 bits (212), Expect = 6e-16 Identities = 137/619 (22%), Positives = 202/619 (32%), Gaps = 95/619 (15%) Query: 1969 TANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPT- 2027 T + P P T + K+A T P E A K +A + +E PT Sbjct: 212 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK-----SAPTTPKEPAPTT 266 Query: 2028 ---PSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAA 2084 P+P +P + A + + S TP+ + KP T PAP+ Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK--- 323 Query: 2085 CAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAW 2144 P+PT+ P P +E T+P P +P P P++ Sbjct: 324 -EPTPTT----PKEPAPTTKEPAPTTPKE-------PAPTAPKKPAPTTPKEP------- 364 Query: 2145 APLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGS 2204 AP + TT + +P P TT + +P P + Sbjct: 365 APTTPKEPAPTTTKEPSPTTPKEPAPTTT----------------KSAPTTTKEPAPTTT 408 Query: 2205 VSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTP 2264 SA T TPK+ + P +++ T+P +P T P Sbjct: 409 KSAPT------TPKEPS---PTTTKEP-------APTTPKEPAPTTPKKPAPTTPKEPAP 452 Query: 2265 TGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEP 2324 T + A P P + P T P +P+ +L PT P Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTP-------KETAPTTPKKL----------TPTTP 495 Query: 2325 PTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPS 2384 L P+ PA E + PE+P TP T A P+ P+T TT Sbjct: 496 EKLAPTTPEKPAPTTPE-ELAPTTPEEP-TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553 Query: 2385 STASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPV 2444 + + +P + + + TP+G P LK+ + KKPA E + P Sbjct: 554 PAPTTPKEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS-T 610 Query: 2445 TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPL---EPLAQKCQPPRKK 2501 TC+ A + G + K P P P EP+P P EP + P K Sbjct: 611 TCDKPAPTTPKGTAPTTPK----EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 666 Query: 2502 SHRVSGKERPNHSRGDPSHVTQP---PPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVK 2558 + + P + D T P P + P P P PT EV Sbjct: 667 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 726 Query: 2559 TPASKPRPDQAREDELHPK 2577 T +P DE P+ Sbjct: 727 TTTKEPTTIHKSPDESTPE 745 Score = 85.5 bits (210), Expect = 9e-16 Identities = 140/645 (21%), Positives = 210/645 (32%), Gaps = 128/645 (19%) Query: 873 PSGPRGPSSGHPLK------SKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKT 926 P+ P+ P+S P + A TP+ AP +A P+ P P PA PK Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 277 Query: 927 RSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL 986 APT P+ + K + P++ Sbjct: 278 P----APTTTKEPAPTTTKSAPTTPK---------------------EPAPTTPKK---- 308 Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046 P P P+ AP + +P P P+ P T P P K Sbjct: 309 -----PAPTTPKEPAPTTPKEPTPTTPKE---PAPTTKEPAPTTPKEPAPTAPKKPAPTT 360 Query: 1047 GKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKE-VELTQGPRED 1105 KE ++ + ++E P+ P + KE T Sbjct: 361 PKEPAPTTPKE-------PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413 Query: 1106 EPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCAD 1165 P++P +E AP P+EP + P + P P T +E P Sbjct: 414 TPKEPSPTTTKEP----APTTPKEPAPTTP---KKPAPTTPKEPAPT--TPKEPAPTTTK 464 Query: 1166 RPS-VAPKDPLQ--------------VPTNTETSEETRPSLDFPQEAKE--PETAEESAP 1208 +P+ PK+P PT E T P P +E P T EE P Sbjct: 465 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524 Query: 1209 DSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTP 1268 + E E + P A A P P++P P+ P A T P G++PT Sbjct: 525 TTPE--EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 582 Query: 1269 GVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVA--NPSSTACPKPSVLSSKISSFGC 1326 + P K P ++ LAP P+ST C KP+ + K ++ Sbjct: 583 -----------LKEPAPTTPKKPAPKE----LAPTTTKEPTSTTCDKPAPTTPKGTA--- 624 Query: 1327 DPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHP----KPSARDAPPA 1382 P K P P ++P PK A L+E P KP+ ++ P Sbjct: 625 ------------PTTPKEPAP-TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 671 Query: 1383 SSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYG 1442 ++ G + + + P +P TA T P A + + P+ P PP Sbjct: 672 TTK-----GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP-----PPTTS 721 Query: 1443 SLSANRDSGLPFACADPPQKTVP--SDPPYPSFLLLEEVSPMLPS 1485 +S + P P ++ P S P P L P +P+ Sbjct: 722 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 766 Score = 78.6 bits (192), Expect = 1e-13 Identities = 144/656 (21%), Positives = 220/656 (33%), Gaps = 116/656 (17%) Query: 992 PRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELI 1051 P P + AP + +PAP + A P T+S+ P K+ A Sbjct: 262 PAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKSAPTTPKEPAPTTPKKPA---------- 310 Query: 1052 LKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPR 1111 + +E P+ P + KE T P+E P P+ Sbjct: 311 ---------------PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT-PKEPAPTAPK 354 Query: 1112 KAARQEAGGDGAPANPEEPGGS---RPGPGRSPQARGPSRSLETGAAAREGGPKCADRPS 1168 K A + AP P+EP + P P +P+ P+ + +E P Sbjct: 355 KPA-PTTPKEPAPTTPKEPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412 Query: 1169 VAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEM 1228 PK+P PT T+ T P KEP P T E + P A Sbjct: 413 TTPKEP--SPTTTKEPAPTTP--------KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462 Query: 1229 GASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNS 1288 P P++P P+ TPK + A T P +PT T ++ + Sbjct: 463 TKKPAPTTPKEPAPT-----TPKET---APTTPKKLTPT------------TPEKLAPTT 502 Query: 1289 KDPPARQPGEFLAPVA----NPSSTACPKPSVLSSKISSFGCDPAGFN-RDPLGVPVAKK 1343 + PA E LAP P++ P P+ + + +PA ++P P K Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPK 560 Query: 1344 GPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP----------PASSSCLCQDGED 1393 P P ++P PK A L+E P + AP P S++C Sbjct: 561 EPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619 Query: 1394 AGSLEPQLPRSPPGTAETEPG----RAASPPTL-ESSSLFPDLPVDRFDPP--LYGSLSA 1446 P P+ P T EP + +P TL E + P P + P G S Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 679 Query: 1447 NRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTV 1506 D P P++T P+ P P+ ++ +P P P + +V + T E T Sbjct: 680 TSDKPAP----TTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTT 734 Query: 1507 VPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESV 1566 + H S DE + L+ S G P A + Sbjct: 735 I--------------------HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT- 773 Query: 1567 GRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAV 1622 + E+ T + + R + T E T +A +T+ +T + AT V Sbjct: 774 -KPEMTTTAKDKTTERDLRTT--PETTTAAPKMTKETATTTEKTTESKITATTTQV 826 Score = 73.2 bits (178), Expect = 5e-12 Identities = 111/481 (23%), Positives = 167/481 (34%), Gaps = 71/481 (14%) Query: 10 PPPTMTGDLQPRQVASSPGHPSQP---------PLEDNTPATRTTKG------------A 48 P PT T + P S+P P +P P PA T K Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337 Query: 49 REAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRL 108 +E P A + A +P + P+ T K SP TP +P S Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397 Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168 E +P ++++ PT TP+ P + P TP+ P P +P P Sbjct: 398 TTTKEPAP--------TTTKSAPT---TPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PT 445 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSY-PEY 227 T +PA +EP T+T +P+ TP+ PAP P+ T+P P P Sbjct: 446 TPKEPAPTTP------KEPAP--TTTKKPAPT-TPKEPAPTTPKE--TAPTTPKKLTPTT 494 Query: 228 QASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287 A + P + P P EP P +P+ + P +P Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554 Query: 288 FPADVAGHAFTNGPLVFAFHQPQGAWP---EEAVGTGPAYPLPTQPAPS----------- 333 P A T P A P+G P +E T P P P + AP+ Sbjct: 555 APTTPKEPAPTT-PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 613 Query: 334 -PLPCYQGQPGGLNRHSDLSGALSSP-GAAHSAPRPFSDSLHKSLTKILPERPPSAQDGL 391 P P P G + A ++P A + P+ + + K P++P + Sbjct: 614 KPAPT---TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 670 Query: 392 GSTRGPPSSLPQRHFPGQAYRASGVDTSP-GPPDTELAAPGPPPARLPQLWDPTAAPYPT 450 +T+GP S+ + P + +T+P P + P P P+ PT + T Sbjct: 671 TTTKGPTSTTSDKPAP-----TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725 Query: 451 P 451 P Sbjct: 726 P 726 Score = 71.6 bits (174), Expect = 1e-11 Identities = 123/549 (22%), Positives = 176/549 (32%), Gaps = 65/549 (11%) Query: 152 TPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPP 211 T +GP P P P T +PA+ P T T S TP+ PAP Sbjct: 204 TTKGPALTTPKEP-TPTTPKEPASTT----------PKEPTPTTIKSAPTTPKEPAPTTT 252 Query: 212 QSRGTSPLQPGSYPEYQASGADSWPPA---AENSFPGANFGVPPAEPEPIPKGSRPGGSP 268 +S T+P +P + + PA + P P EP P + P Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK---KP 309 Query: 269 RGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPT 328 + + P P T P + A +P P+E T P P PT Sbjct: 310 APTTPKEPAPTTPKEPTPTTPKEPAP----------TTKEPAPTTPKEPAPTAPKKPAPT 359 Query: 329 QP-APSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSA 387 P P+P + P S + +P SAP + + TK P P Sbjct: 360 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTP--K 416 Query: 388 QDGLGSTRGPPSSLPQRHFPGQAYR---------ASGVDTSPGPPDTELAAPGPPPARLP 438 + +T+ P + P+ P + A P P T+ AP P P Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476 Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGM 498 TA PT P T P + AP + PT P Sbjct: 477 TTPKETA---PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 533 Query: 499 EMLSRLPFPAGGPEWQGGSQGALGTAGKTPGP-REKLPAVRSSQGGSPALFTYNGMTDP- 556 + P P + A T K P P K A + +G +P T P Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPA-PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592 Query: 557 -----------GAQPLFFGVAQP-QVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGST 604 +P +P +P GT P +P E P P+ TA +T Sbjct: 593 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE-PAPTTPKGTAPTT 651 Query: 605 CSSLSPMSSSPANPSSEE---SQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHY 661 P ++P P+ +E + GP ++ PT P+ET +P EP + P Sbjct: 652 LK--EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKP 708 Query: 662 QPEPAKAFP 670 P + P Sbjct: 709 APTTPETPP 717 Score = 71.2 bits (173), Expect = 2e-11 Identities = 111/492 (22%), Positives = 175/492 (35%), Gaps = 60/492 (12%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPP--PRGSSPILSEGSLPALLHLCS 3485 P P + T P + A AP ++ P P+ +P ++ P Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP---K 386 Query: 3486 EVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDG 3545 E AP+TTK P T + P P+ + P P P + + Sbjct: 387 EPAPTTTKSAPTTTKEPA------------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434 Query: 3546 ALERPENEA--SPGSPGPLL-QQALPLGASLPRPGARGQDAEG---KRAPLVFSGKRRAP 3599 A P+ A +P P P ++ P P P + A + AP + K+ P Sbjct: 435 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT--TPKKLTP 492 Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAS 3659 + AP ++ E+ ++ E T + + T P ++ A + Sbjct: 493 TTPEKLAPTTPEKPAPTTPEELAPTT---PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549 Query: 3660 TPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGG 3719 TP + P P++ + P E A T G P T K +P P++ +P+ T Sbjct: 550 TPKEPA--PTTPKEPAPT-TPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPT--- 602 Query: 3720 SQPQPASGQLQSETATTP--AKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSL 3777 + +P S TTP P+ P + PAP P+E P G+ Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTT-------------PKEPAPTTPKGTA 648 Query: 3778 GPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPTKP 3834 K + T KK P P + G + DKP P TP++ A TP PT P Sbjct: 649 PTTLKEPAPTTPKK---PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 705 Query: 3835 KPNSQNKPR-PPPSEQRKAEPGHTQRKDRLGKAFPQGRPLL--RPPKRGTAVHGAEPAEP 3891 K + P PPP+ + P T+ + K+ + P L P + EP P Sbjct: 706 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 765 Query: 3892 HTHRTAEAQSDL 3903 T A + ++ Sbjct: 766 TTKTPAATKPEM 777 Score = 69.3 bits (168), Expect = 7e-11 Identities = 141/699 (20%), Positives = 218/699 (31%), Gaps = 76/699 (10%) Query: 15 TGDLQPRQVASSPG---------HPSQPPLEDN---------------TPATRTTKGARE 50 T Q +V++SP PS PP D T T TT Sbjct: 104 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 163 Query: 51 AGGQAQAMELPEAQPRQARDG-ELKPPS--LRGQAPSSTPGKRGSPQTPPGRSPLQAPSR 107 G+ + E Q + +L P S L P + +G T P P Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 223 Query: 108 LAGRAEGSPPQRYILGIASSRTKP------TLDETPENPQLEAAQLPEVDTPQGPGTGAP 161 A P I ++ +P + TP+ P + P TP+ P Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 283 Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEP------------PSSFTSTNYTSPSATPRPPAPG 209 P T++ P + ++P P T T P+ T + PAP Sbjct: 284 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343 Query: 210 PPQSRG-TSPLQPG-SYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGS 267 P+ T+P +P + P+ A P P P EP P S P + Sbjct: 344 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT---TPKEPAPTTTKSAPTTT 400 Query: 268 PRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLP 327 PA + P T P +P P++ T P P P Sbjct: 401 KE--------PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452 Query: 328 TQPA-PSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-P 385 T P P+P + P + + ++P + P+ + + + L PE+P P Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP----TTPKKLTPTTPEKLAPTTPEKPAP 508 Query: 386 SAQDGLGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDP 443 + + L T P + P+ P +A+ +T P T P P + P P Sbjct: 509 TTPEELAPTTPEEPTPTTPEEPAPTTP-KAAAPNTPKEPAPTTPKEPAPTTPKEPA---P 564 Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503 T P T P P + P+ ++ + AP + T P Sbjct: 565 TT-PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623 Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSP---ALFTYNGMTDPGAQP 560 P P + A T T K PA + + +P A T G T + Sbjct: 624 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 683 Query: 561 LFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSS 620 P+ + TP P P +P P T + ST ++ ++ +P Sbjct: 684 P--APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 741 Query: 621 EESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPT 659 +L P A + P P + P+ P T Sbjct: 742 STPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780 Score = 64.7 bits (156), Expect = 2e-09 Identities = 122/535 (22%), Positives = 180/535 (33%), Gaps = 82/535 (15%) Query: 1969 TANQLQPENGVSPGGTDNHASVNASPKTAL-TGPTEGAVLLEKCKGSRAAMSLQEEAEPT 2027 T + P P T +PK T P E A ++ A + +E PT Sbjct: 297 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE-----PAPTTPKEPAPT 351 Query: 2028 ----PSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLA 2083 P+P +P + A + + T + +P K T PAP+ A Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411 Query: 2084 ACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPA 2143 P S P+E T+P + PA + ++P Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKK---------PAPTTPKEP------------ 450 Query: 2144 WAPLEEADGVQATTDTGAEDSPVAPPSLT---TSPCDPKEALAGCLLQGEGSPLEDPSSW 2200 AP + TT A +P P T T+P PK+ + + E P+ Sbjct: 451 -APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 509 Query: 2201 PPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGL 2260 P ++ TP++ T PE+ T+P A +P T Sbjct: 510 TPEELAPT-------TPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPK 552 Query: 2261 SSTPTGDEAQAGRGLPGPDPQS-RGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTA 2319 PT + A P + +G P T + P +P A +E + T Sbjct: 553 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 612 Query: 2320 VPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPS----TGL 2375 P T +G P +P + T+ KEP P TP+ K P T P L Sbjct: 613 DKPAPTTPKGTAPTTP---KEPAPTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKEL 668 Query: 2376 GLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQW 2435 T P+ST SD +P + + + TP K+ + KKPA T Sbjct: 669 APTTTKGPTSTTSD--KPAPTTPKETAPTTP----------KEPAPTTPKKPAPT----- 711 Query: 2436 KGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEP 2490 + P P T EV + P + HK+ P AEP+P AL P EP Sbjct: 712 TPETP-PPTTSEVSTPTTTKEP-TTIHKS-PDESTPELSAEPTPKAL-ENSPKEP 762 Score = 63.9 bits (154), Expect = 3e-09 Identities = 103/426 (24%), Positives = 150/426 (35%), Gaps = 37/426 (8%) Query: 3486 EVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDG 3545 E AP+TTK P T + P T P+ +E P P+ + PA Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKE----PAPTTPKE-PAPTTTKEPA-------PTTTKS 293 Query: 3546 ALERPENEA--SPGSPGPLL-QQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGAR 3602 A P+ A +P P P ++ P P P + A + P + K AP A Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353 Query: 3603 GRCAPDHFQED-HLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTP 3661 + AP +E KE +++ S P+ + + T +++K+ A +T Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK----EPAPTTTKSAPTTTKE-PAPTTT 408 Query: 3662 SKALKFPVHP----RKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717 A P P K P E A T P TPK +P P++ +P TK Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTT-TKKP 466 Query: 3718 GGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSL 3777 + P+ + ETA T K P+ PE+L K P E P Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523 Query: 3778 GPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPT-- 3832 + + T K P AP+ P +P P TP++ A TP PT Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 583 Query: 3833 -KPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEP 3891 +P P + KP P + + D+ P+G PK EPA Sbjct: 584 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG-TAPTTPKEPAPTTPKEPAPT 642 Query: 3892 HTHRTA 3897 TA Sbjct: 643 TPKGTA 648 Score = 59.7 bits (143), Expect = 6e-08 Identities = 91/392 (23%), Positives = 139/392 (35%), Gaps = 28/392 (7%) Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRS--PQARGPSRSLETGAAAREGGPKCADR 1166 KP A G A P+EP + P S P+ P+ +E P Sbjct: 196 KPTPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254 Query: 1167 PSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP-ETAEESAPDSTEFTEALRSPPAACA 1225 PK+P PT T+ T P P KEP T +SAP + + E + P A Sbjct: 255 APTTPKEP--APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK--EPAPTTPKKPA 310 Query: 1226 GEMGASPGLLIPEQPPPS-----RHDTGTPKPS--GSLANTAPHGSSPTPGVGSLLGGPG 1278 P P++P P+ T P P+ A TAP +PT P Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP---APT 367 Query: 1279 GTQAPVSHNSKDPPARQPGEFLAPVAN---PSSTACPKPSVLSSKISSFGCDPAGFNRDP 1335 + P +K+P P E AP P++T P P+ S ++ ++P Sbjct: 368 TPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 426 Query: 1336 LGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAG 1395 P K P P ++P PK+ A +E P + + AP ++ Sbjct: 427 --APTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483 Query: 1396 SLEPQ--LPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRF-DPPLYGSLSANRDSGL 1452 P+ P +P A T P + A E + P+ P + P + A + Sbjct: 484 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 543 Query: 1453 PFACADPPQKTVPSDPPYPSFLLLEEVSPMLP 1484 P++ P+ P P+ +E +P P Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 575 Score = 58.2 bits (139), Expect = 2e-07 Identities = 161/778 (20%), Positives = 236/778 (30%), Gaps = 126/778 (16%) Query: 568 PQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTC-------SSLSPMSSSPANPSS 620 P+ TP P P + ++P+ P+P T + T ++ P ++P P+ Sbjct: 221 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280 Query: 621 EESQLPGPLGPSAFFHPPTHPQETGSPFPSP----EPPHSLPTHYQP----EPAKAFPFP 672 ++ P P + P P T P+P EP + P P EPA P Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340 Query: 673 ADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLT 732 A E A T P + P+ P P T S + + T Sbjct: 341 APTTPKEPA-----PTAPKKPAPTTPKEPAPTTPKEPAPTTTKE---PSPTTPKEPAPTT 392 Query: 733 CRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSP-PAAPRVPADAHAGLL 791 + A ++ + P P P P P+ PA Sbjct: 393 TKSAPTTTKEPAP----------TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 442 Query: 792 SHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGM 851 + A E + P+ P P + KL E L Sbjct: 443 APTTPKEPAPTTPKEPAPTTTKKP-APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501 Query: 852 EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911 + P EEP+ P P P KA K P P P P TP Sbjct: 502 TPEKPAPTTPEELAPT-TPEEPT-PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559 Query: 912 RPGDRGCPARGRPKTRSLGLAPT--EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGS 969 + P P T G APT + AP+ ++ + K+ S + + + Sbjct: 560 KEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618 Query: 970 GGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAA---LPEETRSSR 1026 G A P P+ AP + +PAP P+ A L E ++ Sbjct: 619 TPKGTA------------------PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 660 Query: 1027 RRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGR 1086 ++ P P K S ++P P P Sbjct: 661 KKPAPKELAPTTTK--------------------------GPTSTTSDKPAPTTP----- 689 Query: 1087 RGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGG-----SRPGPGRSP 1141 KE T P+E P P+K AP PE P S P + P Sbjct: 690 -------KETAPTT-PKEPAPTTPKKP---------APTTPETPPPTTSEVSTPTTTKEP 732 Query: 1142 QARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPE 1201 S T + E PK + +PK+P VPT T+T T+P + + K E Sbjct: 733 TTIHKSPDESTPELSAEPTPKALEN---SPKEP-GVPT-TKTPAATKPEMTTTAKDKTTE 787 Query: 1202 TAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANT-- 1259 + P++T + A + S Q + TP +L T Sbjct: 788 RDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 847 Query: 1260 APH--GSSPTPGVGSLLGGPGGTQAPVSH--NSKDPPARQPGEFLAPVANPSSTACPK 1313 AP + T ++ P T P NSK + AP P+ST PK Sbjct: 848 APKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP-KKPTSTKKPK 904 Score = 55.8 bits (133), Expect = 8e-07 Identities = 140/683 (20%), Positives = 220/683 (32%), Gaps = 121/683 (17%) Query: 2193 PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKE-KLWESPGRATSPPLAGAVSP 2251 P+ S PP S DT K+++L + +++ E K + + TS G Sbjct: 123 PINPRPSLPPNS----------DTSKETSLTVNKETTVETKETTTTNKQTSTD--GKEKT 170 Query: 2252 SVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGH 2311 + A + T D A + L P P++ + +G + +P Sbjct: 171 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKA---------ETTTKGPALTTPKEPTPTTP 221 Query: 2312 REGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCP 2371 +E + T P T++ A T+ KEP P T +S T P+ P Sbjct: 222 KEPASTTPKEPTPTTIKSAP------------TTPKEP----APTTTKSAPTT-PKEPAP 264 Query: 2372 STGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTE 2431 +T T P+ T + +P + + + T + P P K+ + KKPA T Sbjct: 265 TT------TKEPAPTTP--KEPAPTTTKEPAPTTTKSAPTTP---KEPAPTTPKKPAPTT 313 Query: 2432 NGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHR-PHPGAPAEPSPAALPAQQPLEP 2490 + P P P + A + P P P EP+P A P P Sbjct: 314 PKEPAPTTPKEPT------------PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361 Query: 2491 LAQKCQPPR-------KKSHRVSGKE-RPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHS 2542 P+ K+ + KE P ++ P+ +P P +K P P Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT-TKSAPTTPKEPSP 420 Query: 2543 QQLHPPSPTEHEVDVKTPASKPRPDQARED-ELHPKQ----AEKREGRRWRREPTVDSPS 2597 P+PT + T KP P +E PK+ K+ +EP +P Sbjct: 421 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 480 Query: 2598 HSEGKSNKKRGKLRGRRL-----------REESILPVSADVISDGRGSRPSPAMASYAA- 2645 + + KK +L E + P + + + P+P AA Sbjct: 481 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 540 Query: 2646 ----SPSHCLSVEGGPEADGEQPPRL-ATLGPGVMEGAAETDQEALCAGETGAQKPPGDR 2700 P+ E P E P P +G A T + T +KP Sbjct: 541 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE--PAPTTPKKPAPKE 598 Query: 2701 M-----------LCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAED 2749 + C G PT K + P T G + EPA Sbjct: 599 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 658 Query: 2750 SSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNP----DTQGGVQG 2805 + + + E T GP TS PA +T P P + Sbjct: 659 TPKKPAPKELA----PTTTKGPTS--TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 712 Query: 2806 PEGPTPDAS----GSSAKDPPSL 2824 PE P P S ++ K+P ++ Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTI 735 Score = 52.8 bits (125), Expect = 7e-06 Identities = 80/353 (22%), Positives = 125/353 (35%), Gaps = 45/353 (12%) Query: 1166 RPSVAPKDPLQVPT----NTETSEETRPSLDFPQE-----------AKEPETAEESAPDS 1210 RPS+ P T N ET+ ET+ + ++ AKE ++ E+++ Sbjct: 127 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 186 Query: 1211 TEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGV 1270 T + + P A P L P++P P+ TPK A+T P +PT Sbjct: 187 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT-----TPKEP---ASTTPKEPTPT--- 235 Query: 1271 GSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAG 1330 ++ P + P +K P P+ T +P+ ++K +PA Sbjct: 236 -TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK------EPAP 288 Query: 1331 FNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQD 1390 P K P P ++P PK+ A +E P AP Sbjct: 289 TTTK--SAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345 Query: 1391 GEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDS 1450 E A P P+ P T EP +++ P P +P + SA + Sbjct: 346 KEPA----PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKEPAPTTTKSAPTTT 400 Query: 1451 GLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPE 1503 P A K+ P+ P PS +E +P P P + K + T P E Sbjct: 401 KEP---APTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PAPTTPKKPAPTTPKE 449 Score = 52.8 bits (125), Expect = 7e-06 Identities = 84/382 (21%), Positives = 124/382 (32%), Gaps = 44/382 (11%) Query: 1151 ETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS 1210 ET + + A V K + T T+ T P P KEP + P Sbjct: 175 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 234 Query: 1211 TEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPT--- 1267 T A +P ++P P++P P T T +P A T P +PT Sbjct: 235 TTIKSAPTTPKEPAPTTTKSAP--TTPKEPAP----TTTKEP----APTTPKEPAPTTTK 284 Query: 1268 -PGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGC 1326 P + P + P K P P E P+ T +P+ + K Sbjct: 285 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE-------PAPTTPKEPTPTTPK------ 331 Query: 1327 DPAGFNRDPL------GVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP 1380 +PA ++P P A K P P ++P PK+ A +E P AP Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAP-TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390 Query: 1381 PASSSCLCQDGEDAGSLEPQLPR-----SPPGTAETEPGRAASPPTLESSSLFPDLPVDR 1435 + S E A + P SP T E P P P P + Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450 Query: 1436 FDPPLYGSLSANRDSGLPFACADP----PQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLS 1491 P +P P++T P+ P + E+++P P P + Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPT 509 Query: 1492 GGKVLSKTCPPERTVVPGAAPS 1513 + L+ T P E T P+ Sbjct: 510 TPEELAPTTPEEPTPTTPEEPA 531 Score = 51.2 bits (121), Expect = 2e-05 Identities = 65/244 (26%), Positives = 94/244 (38%), Gaps = 38/244 (15%) Query: 3659 STPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGG 3718 ST K +++ + +LA ++ KP TPKA+ +P+ T T Sbjct: 163 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP-TPKAETTTKGPALTTPKEPTPT-- 219 Query: 3719 GSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLG 3778 + +PAS + T TT + PAP + A + K P + P + Sbjct: 220 -TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS---APTTPKEPAPTTTKEPAPTT- 274 Query: 3779 PKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPTKPK 3835 PKE ++TK P P ++S AP+ P +P P TP+K A TP PT PK Sbjct: 275 PKEPAPTTTKE-----PAPTTTKS------APTTPKEPAPTTPKKPAPTTPKEPAPTTPK 323 Query: 3836 ---PNSQNKPRP---PPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPA 3889 P + +P P P+ EP T K +P PK EPA Sbjct: 324 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK----------KPAPTTPKEPAPTTPKEPA 373 Query: 3890 EPHT 3893 T Sbjct: 374 PTTT 377 Score = 46.6 bits (109), Expect = 5e-04 Identities = 80/372 (21%), Positives = 115/372 (30%), Gaps = 45/372 (12%) Query: 365 PRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPD 424 P P +++ K P+ P + + P S+ P+ P A P P Sbjct: 197 PTPKAETTTKGPALTTPKEPTPT-----TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT 251 Query: 425 TELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPW 484 T+ +AP P P T P PT P P T +P+P P + P Sbjct: 252 TK-SAPTTPKEPAPTT---TKEPAPTTPKEPAPTTTK-----EPAPTTTKSAPTTPKEPA 302 Query: 485 PQV----LPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPRE-KLPAVRS 539 P PT P + P P E ++ T K P P K PA + Sbjct: 303 PTTPKKPAPTTPKEP--APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360 Query: 540 SQGGSPALFTYNGMT---DPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSP 596 + +P T +P S T P P ++P+ PSP Sbjct: 361 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 420 Query: 597 ATNTAGSTCSSLSPMSSSPANPSSEESQLPGPL-----GPSAFFHP---------PTHPQ 642 T + + P ++P P+ + P P P+ P PT P+ Sbjct: 421 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 480 Query: 643 ETGSPFP---SPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGR 699 ET P +P P L +PA P E E P P + Sbjct: 481 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP----APTTPK 536 Query: 700 GGLQGFPRAPPP 711 P+ P P Sbjct: 537 AAAPNTPKEPAP 548 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 86.3 bits (212), Expect = 6e-16 Identities = 137/619 (22%), Positives = 202/619 (32%), Gaps = 95/619 (15%) Query: 1969 TANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPT- 2027 T + P P T + K+A T P E A K +A + +E PT Sbjct: 253 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK-----SAPTTPKEPAPTT 307 Query: 2028 ---PSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAA 2084 P+P +P + A + + S TP+ + KP T PAP+ Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK--- 364 Query: 2085 CAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAW 2144 P+PT+ P P +E T+P P +P P P++ Sbjct: 365 -EPTPTT----PKEPAPTTKEPAPTTPKE-------PAPTAPKKPAPTTPKEP------- 405 Query: 2145 APLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGS 2204 AP + TT + +P P TT + +P P + Sbjct: 406 APTTPKEPAPTTTKEPSPTTPKEPAPTTT----------------KSAPTTTKEPAPTTT 449 Query: 2205 VSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTP 2264 SA T TPK+ + P +++ T+P +P T P Sbjct: 450 KSAPT------TPKEPS---PTTTKEP-------APTTPKEPAPTTPKKPAPTTPKEPAP 493 Query: 2265 TGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEP 2324 T + A P P + P T P +P+ +L PT P Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTP-------KETAPTTPKKL----------TPTTP 536 Query: 2325 PTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPS 2384 L P+ PA E + PE+P TP T A P+ P+T TT Sbjct: 537 EKLAPTTPEKPAPTTPE-ELAPTTPEEP-TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594 Query: 2385 STASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPV 2444 + + +P + + + TP+G P LK+ + KKPA E + P Sbjct: 595 PAPTTPKEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS-T 651 Query: 2445 TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPL---EPLAQKCQPPRKK 2501 TC+ A + G + K P P P EP+P P EP + P K Sbjct: 652 TCDKPAPTTPKGTAPTTPK----EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 707 Query: 2502 SHRVSGKERPNHSRGDPSHVTQP---PPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVK 2558 + + P + D T P P + P P P PT EV Sbjct: 708 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 767 Query: 2559 TPASKPRPDQAREDELHPK 2577 T +P DE P+ Sbjct: 768 TTTKEPTTIHKSPDESTPE 786 Score = 85.5 bits (210), Expect = 9e-16 Identities = 140/645 (21%), Positives = 210/645 (32%), Gaps = 128/645 (19%) Query: 873 PSGPRGPSSGHPLK------SKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKT 926 P+ P+ P+S P + A TP+ AP +A P+ P P PA PK Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 318 Query: 927 RSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL 986 APT P+ + K + P++ Sbjct: 319 P----APTTTKEPAPTTTKSAPTTPK---------------------EPAPTTPKK---- 349 Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046 P P P+ AP + +P P P+ P T P P K Sbjct: 350 -----PAPTTPKEPAPTTPKEPTPTTPKE---PAPTTKEPAPTTPKEPAPTAPKKPAPTT 401 Query: 1047 GKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKE-VELTQGPRED 1105 KE ++ + ++E P+ P + KE T Sbjct: 402 PKEPAPTTPKE-------PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454 Query: 1106 EPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCAD 1165 P++P +E AP P+EP + P + P P T +E P Sbjct: 455 TPKEPSPTTTKEP----APTTPKEPAPTTP---KKPAPTTPKEPAPT--TPKEPAPTTTK 505 Query: 1166 RPS-VAPKDPLQ--------------VPTNTETSEETRPSLDFPQEAKE--PETAEESAP 1208 +P+ PK+P PT E T P P +E P T EE P Sbjct: 506 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565 Query: 1209 DSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTP 1268 + E E + P A A P P++P P+ P A T P G++PT Sbjct: 566 TTPE--EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 623 Query: 1269 GVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVA--NPSSTACPKPSVLSSKISSFGC 1326 + P K P ++ LAP P+ST C KP+ + K ++ Sbjct: 624 -----------LKEPAPTTPKKPAPKE----LAPTTTKEPTSTTCDKPAPTTPKGTA--- 665 Query: 1327 DPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHP----KPSARDAPPA 1382 P K P P ++P PK A L+E P KP+ ++ P Sbjct: 666 ------------PTTPKEPAP-TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 712 Query: 1383 SSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYG 1442 ++ G + + + P +P TA T P A + + P+ P PP Sbjct: 713 TTK-----GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP-----PPTTS 762 Query: 1443 SLSANRDSGLPFACADPPQKTVP--SDPPYPSFLLLEEVSPMLPS 1485 +S + P P ++ P S P P L P +P+ Sbjct: 763 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 807 Score = 78.6 bits (192), Expect = 1e-13 Identities = 144/656 (21%), Positives = 220/656 (33%), Gaps = 116/656 (17%) Query: 992 PRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELI 1051 P P + AP + +PAP + A P T+S+ P K+ A Sbjct: 303 PAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKSAPTTPKEPAPTTPKKPA---------- 351 Query: 1052 LKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPR 1111 + +E P+ P + KE T P+E P P+ Sbjct: 352 ---------------PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT-PKEPAPTAPK 395 Query: 1112 KAARQEAGGDGAPANPEEPGGS---RPGPGRSPQARGPSRSLETGAAAREGGPKCADRPS 1168 K A + AP P+EP + P P +P+ P+ + +E P Sbjct: 396 KPA-PTTPKEPAPTTPKEPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453 Query: 1169 VAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEM 1228 PK+P PT T+ T P KEP P T E + P A Sbjct: 454 TTPKEP--SPTTTKEPAPTTP--------KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503 Query: 1229 GASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNS 1288 P P++P P+ TPK + A T P +PT T ++ + Sbjct: 504 TKKPAPTTPKEPAPT-----TPKET---APTTPKKLTPT------------TPEKLAPTT 543 Query: 1289 KDPPARQPGEFLAPVA----NPSSTACPKPSVLSSKISSFGCDPAGFN-RDPLGVPVAKK 1343 + PA E LAP P++ P P+ + + +PA ++P P K Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPK 601 Query: 1344 GPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP----------PASSSCLCQDGED 1393 P P ++P PK A L+E P + AP P S++C Sbjct: 602 EPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660 Query: 1394 AGSLEPQLPRSPPGTAETEPG----RAASPPTL-ESSSLFPDLPVDRFDPP--LYGSLSA 1446 P P+ P T EP + +P TL E + P P + P G S Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 720 Query: 1447 NRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTV 1506 D P P++T P+ P P+ ++ +P P P + +V + T E T Sbjct: 721 TSDKPAP----TTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTT 775 Query: 1507 VPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESV 1566 + H S DE + L+ S G P A + Sbjct: 776 I--------------------HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT- 814 Query: 1567 GRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAV 1622 + E+ T + + R + T E T +A +T+ +T + AT V Sbjct: 815 -KPEMTTTAKDKTTERDLRTT--PETTTAAPKMTKETATTTEKTTESKITATTTQV 867 Score = 73.2 bits (178), Expect = 5e-12 Identities = 111/481 (23%), Positives = 167/481 (34%), Gaps = 71/481 (14%) Query: 10 PPPTMTGDLQPRQVASSPGHPSQP---------PLEDNTPATRTTKG------------A 48 P PT T + P S+P P +P P PA T K Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378 Query: 49 REAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRL 108 +E P A + A +P + P+ T K SP TP +P S Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438 Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168 E +P ++++ PT TP+ P + P TP+ P P +P P Sbjct: 439 TTTKEPAP--------TTTKSAPT---TPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PT 486 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSY-PEY 227 T +PA +EP T+T +P+ TP+ PAP P+ T+P P P Sbjct: 487 TPKEPAPTTP------KEPAP--TTTKKPAPT-TPKEPAPTTPKE--TAPTTPKKLTPTT 535 Query: 228 QASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287 A + P + P P EP P +P+ + P +P Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595 Query: 288 FPADVAGHAFTNGPLVFAFHQPQGAWP---EEAVGTGPAYPLPTQPAPS----------- 333 P A T P A P+G P +E T P P P + AP+ Sbjct: 596 APTTPKEPAPTT-PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 654 Query: 334 -PLPCYQGQPGGLNRHSDLSGALSSP-GAAHSAPRPFSDSLHKSLTKILPERPPSAQDGL 391 P P P G + A ++P A + P+ + + K P++P + Sbjct: 655 KPAPT---TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 711 Query: 392 GSTRGPPSSLPQRHFPGQAYRASGVDTSP-GPPDTELAAPGPPPARLPQLWDPTAAPYPT 450 +T+GP S+ + P + +T+P P + P P P+ PT + T Sbjct: 712 TTTKGPTSTTSDKPAP-----TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766 Query: 451 P 451 P Sbjct: 767 P 767 Score = 71.6 bits (174), Expect = 1e-11 Identities = 123/549 (22%), Positives = 176/549 (32%), Gaps = 65/549 (11%) Query: 152 TPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPP 211 T +GP P P P T +PA+ P T T S TP+ PAP Sbjct: 245 TTKGPALTTPKEP-TPTTPKEPASTT----------PKEPTPTTIKSAPTTPKEPAPTTT 293 Query: 212 QSRGTSPLQPGSYPEYQASGADSWPPA---AENSFPGANFGVPPAEPEPIPKGSRPGGSP 268 +S T+P +P + + PA + P P EP P + P Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK---KP 350 Query: 269 RGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPT 328 + + P P T P + A +P P+E T P P PT Sbjct: 351 APTTPKEPAPTTPKEPTPTTPKEPAP----------TTKEPAPTTPKEPAPTAPKKPAPT 400 Query: 329 QP-APSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSA 387 P P+P + P S + +P SAP + + TK P P Sbjct: 401 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTP--K 457 Query: 388 QDGLGSTRGPPSSLPQRHFPGQAYR---------ASGVDTSPGPPDTELAAPGPPPARLP 438 + +T+ P + P+ P + A P P T+ AP P P Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517 Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGM 498 TA PT P T P + AP + PT P Sbjct: 518 TTPKETA---PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 574 Query: 499 EMLSRLPFPAGGPEWQGGSQGALGTAGKTPGP-REKLPAVRSSQGGSPALFTYNGMTDP- 556 + P P + A T K P P K A + +G +P T P Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPA-PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633 Query: 557 -----------GAQPLFFGVAQP-QVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGST 604 +P +P +P GT P +P E P P+ TA +T Sbjct: 634 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE-PAPTTPKGTAPTT 692 Query: 605 CSSLSPMSSSPANPSSEE---SQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHY 661 P ++P P+ +E + GP ++ PT P+ET +P EP + P Sbjct: 693 LK--EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKP 749 Query: 662 QPEPAKAFP 670 P + P Sbjct: 750 APTTPETPP 758 Score = 71.2 bits (173), Expect = 2e-11 Identities = 111/492 (22%), Positives = 175/492 (35%), Gaps = 60/492 (12%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPP--PRGSSPILSEGSLPALLHLCS 3485 P P + T P + A AP ++ P P+ +P ++ P Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP---K 427 Query: 3486 EVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDG 3545 E AP+TTK P T + P P+ + P P P + + Sbjct: 428 EPAPTTTKSAPTTTKEPA------------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475 Query: 3546 ALERPENEA--SPGSPGPLL-QQALPLGASLPRPGARGQDAEG---KRAPLVFSGKRRAP 3599 A P+ A +P P P ++ P P P + A + AP + K+ P Sbjct: 476 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT--TPKKLTP 533 Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAS 3659 + AP ++ E+ ++ E T + + T P ++ A + Sbjct: 534 TTPEKLAPTTPEKPAPTTPEELAPTT---PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590 Query: 3660 TPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGG 3719 TP + P P++ + P E A T G P T K +P P++ +P+ T Sbjct: 591 TPKEPA--PTTPKEPAPT-TPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPT--- 643 Query: 3720 SQPQPASGQLQSETATTP--AKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSL 3777 + +P S TTP P+ P + PAP P+E P G+ Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTT-------------PKEPAPTTPKGTA 689 Query: 3778 GPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPTKP 3834 K + T KK P P + G + DKP P TP++ A TP PT P Sbjct: 690 PTTLKEPAPTTPKK---PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 746 Query: 3835 KPNSQNKPR-PPPSEQRKAEPGHTQRKDRLGKAFPQGRPLL--RPPKRGTAVHGAEPAEP 3891 K + P PPP+ + P T+ + K+ + P L P + EP P Sbjct: 747 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 806 Query: 3892 HTHRTAEAQSDL 3903 T A + ++ Sbjct: 807 TTKTPAATKPEM 818 Score = 69.3 bits (168), Expect = 7e-11 Identities = 141/699 (20%), Positives = 218/699 (31%), Gaps = 76/699 (10%) Query: 15 TGDLQPRQVASSPG---------HPSQPPLEDN---------------TPATRTTKGARE 50 T Q +V++SP PS PP D T T TT Sbjct: 145 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 204 Query: 51 AGGQAQAMELPEAQPRQARDG-ELKPPS--LRGQAPSSTPGKRGSPQTPPGRSPLQAPSR 107 G+ + E Q + +L P S L P + +G T P P Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 264 Query: 108 LAGRAEGSPPQRYILGIASSRTKP------TLDETPENPQLEAAQLPEVDTPQGPGTGAP 161 A P I ++ +P + TP+ P + P TP+ P Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 324 Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEP------------PSSFTSTNYTSPSATPRPPAPG 209 P T++ P + ++P P T T P+ T + PAP Sbjct: 325 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384 Query: 210 PPQSRG-TSPLQPG-SYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGS 267 P+ T+P +P + P+ A P P P EP P S P + Sbjct: 385 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT---TPKEPAPTTTKSAPTTT 441 Query: 268 PRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLP 327 PA + P T P +P P++ T P P P Sbjct: 442 KE--------PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493 Query: 328 TQPA-PSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-P 385 T P P+P + P + + ++P + P+ + + + L PE+P P Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP----TTPKKLTPTTPEKLAPTTPEKPAP 549 Query: 386 SAQDGLGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDP 443 + + L T P + P+ P +A+ +T P T P P + P P Sbjct: 550 TTPEELAPTTPEEPTPTTPEEPAPTTP-KAAAPNTPKEPAPTTPKEPAPTTPKEPA---P 605 Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503 T P T P P + P+ ++ + AP + T P Sbjct: 606 TT-PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664 Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSP---ALFTYNGMTDPGAQP 560 P P + A T T K PA + + +P A T G T + Sbjct: 665 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 724 Query: 561 LFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSS 620 P+ + TP P P +P P T + ST ++ ++ +P Sbjct: 725 P--APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 782 Query: 621 EESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPT 659 +L P A + P P + P+ P T Sbjct: 783 STPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821 Score = 64.7 bits (156), Expect = 2e-09 Identities = 122/535 (22%), Positives = 180/535 (33%), Gaps = 82/535 (15%) Query: 1969 TANQLQPENGVSPGGTDNHASVNASPKTAL-TGPTEGAVLLEKCKGSRAAMSLQEEAEPT 2027 T + P P T +PK T P E A ++ A + +E PT Sbjct: 338 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE-----PAPTTPKEPAPT 392 Query: 2028 ----PSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLA 2083 P+P +P + A + + T + +P K T PAP+ A Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452 Query: 2084 ACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPA 2143 P S P+E T+P + PA + ++P Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKK---------PAPTTPKEP------------ 491 Query: 2144 WAPLEEADGVQATTDTGAEDSPVAPPSLT---TSPCDPKEALAGCLLQGEGSPLEDPSSW 2200 AP + TT A +P P T T+P PK+ + + E P+ Sbjct: 492 -APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 550 Query: 2201 PPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGL 2260 P ++ TP++ T PE+ T+P A +P T Sbjct: 551 TPEELAPT-------TPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPK 593 Query: 2261 SSTPTGDEAQAGRGLPGPDPQS-RGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTA 2319 PT + A P + +G P T + P +P A +E + T Sbjct: 594 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 653 Query: 2320 VPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPS----TGL 2375 P T +G P +P + T+ KEP P TP+ K P T P L Sbjct: 654 DKPAPTTPKGTAPTTP---KEPAPTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKEL 709 Query: 2376 GLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQW 2435 T P+ST SD +P + + + TP K+ + KKPA T Sbjct: 710 APTTTKGPTSTTSD--KPAPTTPKETAPTTP----------KEPAPTTPKKPAPT----- 752 Query: 2436 KGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEP 2490 + P P T EV + P + HK+ P AEP+P AL P EP Sbjct: 753 TPETP-PPTTSEVSTPTTTKEP-TTIHKS-PDESTPELSAEPTPKAL-ENSPKEP 803 Score = 63.9 bits (154), Expect = 3e-09 Identities = 103/426 (24%), Positives = 150/426 (35%), Gaps = 37/426 (8%) Query: 3486 EVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDG 3545 E AP+TTK P T + P T P+ +E P P+ + PA Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKE----PAPTTPKE-PAPTTTKEPA-------PTTTKS 334 Query: 3546 ALERPENEA--SPGSPGPLL-QQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGAR 3602 A P+ A +P P P ++ P P P + A + P + K AP A Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394 Query: 3603 GRCAPDHFQED-HLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTP 3661 + AP +E KE +++ S P+ + + T +++K+ A +T Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK----EPAPTTTKSAPTTTKE-PAPTTT 449 Query: 3662 SKALKFPVHP----RKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717 A P P K P E A T P TPK +P P++ +P TK Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTT-TKKP 507 Query: 3718 GGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSL 3777 + P+ + ETA T K P+ PE+L K P E P Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564 Query: 3778 GPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPT-- 3832 + + T K P AP+ P +P P TP++ A TP PT Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 624 Query: 3833 -KPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEP 3891 +P P + KP P + + D+ P+G PK EPA Sbjct: 625 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG-TAPTTPKEPAPTTPKEPAPT 683 Query: 3892 HTHRTA 3897 TA Sbjct: 684 TPKGTA 689 Score = 59.7 bits (143), Expect = 6e-08 Identities = 91/392 (23%), Positives = 139/392 (35%), Gaps = 28/392 (7%) Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRS--PQARGPSRSLETGAAAREGGPKCADR 1166 KP A G A P+EP + P S P+ P+ +E P Sbjct: 237 KPTPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295 Query: 1167 PSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP-ETAEESAPDSTEFTEALRSPPAACA 1225 PK+P PT T+ T P P KEP T +SAP + + E + P A Sbjct: 296 APTTPKEP--APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK--EPAPTTPKKPA 351 Query: 1226 GEMGASPGLLIPEQPPPS-----RHDTGTPKPS--GSLANTAPHGSSPTPGVGSLLGGPG 1278 P P++P P+ T P P+ A TAP +PT P Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP---APT 408 Query: 1279 GTQAPVSHNSKDPPARQPGEFLAPVAN---PSSTACPKPSVLSSKISSFGCDPAGFNRDP 1335 + P +K+P P E AP P++T P P+ S ++ ++P Sbjct: 409 TPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 467 Query: 1336 LGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAG 1395 P K P P ++P PK+ A +E P + + AP ++ Sbjct: 468 --APTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524 Query: 1396 SLEPQ--LPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRF-DPPLYGSLSANRDSGL 1452 P+ P +P A T P + A E + P+ P + P + A + Sbjct: 525 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 584 Query: 1453 PFACADPPQKTVPSDPPYPSFLLLEEVSPMLP 1484 P++ P+ P P+ +E +P P Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 616 Score = 58.2 bits (139), Expect = 2e-07 Identities = 161/778 (20%), Positives = 236/778 (30%), Gaps = 126/778 (16%) Query: 568 PQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTC-------SSLSPMSSSPANPSS 620 P+ TP P P + ++P+ P+P T + T ++ P ++P P+ Sbjct: 262 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321 Query: 621 EESQLPGPLGPSAFFHPPTHPQETGSPFPSP----EPPHSLPTHYQP----EPAKAFPFP 672 ++ P P + P P T P+P EP + P P EPA P Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381 Query: 673 ADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLT 732 A E A T P + P+ P P T S + + T Sbjct: 382 APTTPKEPA-----PTAPKKPAPTTPKEPAPTTPKEPAPTTTKE---PSPTTPKEPAPTT 433 Query: 733 CRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSP-PAAPRVPADAHAGLL 791 + A ++ + P P P P P+ PA Sbjct: 434 TKSAPTTTKEPAP----------TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 483 Query: 792 SHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGM 851 + A E + P+ P P + KL E L Sbjct: 484 APTTPKEPAPTTPKEPAPTTTKKP-APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542 Query: 852 EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911 + P EEP+ P P P KA K P P P P TP Sbjct: 543 TPEKPAPTTPEELAPT-TPEEPT-PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600 Query: 912 RPGDRGCPARGRPKTRSLGLAPT--EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGS 969 + P P T G APT + AP+ ++ + K+ S + + + Sbjct: 601 KEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659 Query: 970 GGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAA---LPEETRSSR 1026 G A P P+ AP + +PAP P+ A L E ++ Sbjct: 660 TPKGTA------------------PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 701 Query: 1027 RRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGR 1086 ++ P P K S ++P P P Sbjct: 702 KKPAPKELAPTTTK--------------------------GPTSTTSDKPAPTTP----- 730 Query: 1087 RGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGG-----SRPGPGRSP 1141 KE T P+E P P+K AP PE P S P + P Sbjct: 731 -------KETAPTT-PKEPAPTTPKKP---------APTTPETPPPTTSEVSTPTTTKEP 773 Query: 1142 QARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPE 1201 S T + E PK + +PK+P VPT T+T T+P + + K E Sbjct: 774 TTIHKSPDESTPELSAEPTPKALEN---SPKEP-GVPT-TKTPAATKPEMTTTAKDKTTE 828 Query: 1202 TAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANT-- 1259 + P++T + A + S Q + TP +L T Sbjct: 829 RDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 888 Query: 1260 APH--GSSPTPGVGSLLGGPGGTQAPVSH--NSKDPPARQPGEFLAPVANPSSTACPK 1313 AP + T ++ P T P NSK + AP P+ST PK Sbjct: 889 APKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP-KKPTSTKKPK 945 Score = 55.8 bits (133), Expect = 8e-07 Identities = 140/683 (20%), Positives = 220/683 (32%), Gaps = 121/683 (17%) Query: 2193 PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKE-KLWESPGRATSPPLAGAVSP 2251 P+ S PP S DT K+++L + +++ E K + + TS G Sbjct: 164 PINPRPSLPPNS----------DTSKETSLTVNKETTVETKETTTTNKQTSTD--GKEKT 211 Query: 2252 SVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGH 2311 + A + T D A + L P P++ + +G + +P Sbjct: 212 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKA---------ETTTKGPALTTPKEPTPTTP 262 Query: 2312 REGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCP 2371 +E + T P T++ A T+ KEP P T +S T P+ P Sbjct: 263 KEPASTTPKEPTPTTIKSAP------------TTPKEP----APTTTKSAPTT-PKEPAP 305 Query: 2372 STGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTE 2431 +T T P+ T + +P + + + T + P P K+ + KKPA T Sbjct: 306 TT------TKEPAPTTP--KEPAPTTTKEPAPTTTKSAPTTP---KEPAPTTPKKPAPTT 354 Query: 2432 NGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHR-PHPGAPAEPSPAALPAQQPLEP 2490 + P P P + A + P P P EP+P A P P Sbjct: 355 PKEPAPTTPKEPT------------PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402 Query: 2491 LAQKCQPPR-------KKSHRVSGKE-RPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHS 2542 P+ K+ + KE P ++ P+ +P P +K P P Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT-TKSAPTTPKEPSP 461 Query: 2543 QQLHPPSPTEHEVDVKTPASKPRPDQARED-ELHPKQ----AEKREGRRWRREPTVDSPS 2597 P+PT + T KP P +E PK+ K+ +EP +P Sbjct: 462 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 521 Query: 2598 HSEGKSNKKRGKLRGRRL-----------REESILPVSADVISDGRGSRPSPAMASYAA- 2645 + + KK +L E + P + + + P+P AA Sbjct: 522 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 581 Query: 2646 ----SPSHCLSVEGGPEADGEQPPRL-ATLGPGVMEGAAETDQEALCAGETGAQKPPGDR 2700 P+ E P E P P +G A T + T +KP Sbjct: 582 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE--PAPTTPKKPAPKE 639 Query: 2701 M-----------LCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAED 2749 + C G PT K + P T G + EPA Sbjct: 640 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 699 Query: 2750 SSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNP----DTQGGVQG 2805 + + + E T GP TS PA +T P P + Sbjct: 700 TPKKPAPKELA----PTTTKGPTS--TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 753 Query: 2806 PEGPTPDAS----GSSAKDPPSL 2824 PE P P S ++ K+P ++ Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTI 776 Score = 52.8 bits (125), Expect = 7e-06 Identities = 80/353 (22%), Positives = 125/353 (35%), Gaps = 45/353 (12%) Query: 1166 RPSVAPKDPLQVPT----NTETSEETRPSLDFPQE-----------AKEPETAEESAPDS 1210 RPS+ P T N ET+ ET+ + ++ AKE ++ E+++ Sbjct: 168 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 227 Query: 1211 TEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGV 1270 T + + P A P L P++P P+ TPK A+T P +PT Sbjct: 228 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT-----TPKEP---ASTTPKEPTPT--- 276 Query: 1271 GSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAG 1330 ++ P + P +K P P+ T +P+ ++K +PA Sbjct: 277 -TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK------EPAP 329 Query: 1331 FNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQD 1390 P K P P ++P PK+ A +E P AP Sbjct: 330 TTTK--SAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386 Query: 1391 GEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDS 1450 E A P P+ P T EP +++ P P +P + SA + Sbjct: 387 KEPA----PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKEPAPTTTKSAPTTT 441 Query: 1451 GLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPE 1503 P A K+ P+ P PS +E +P P P + K + T P E Sbjct: 442 KEP---APTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PAPTTPKKPAPTTPKE 490 Score = 52.8 bits (125), Expect = 7e-06 Identities = 84/382 (21%), Positives = 124/382 (32%), Gaps = 44/382 (11%) Query: 1151 ETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS 1210 ET + + A V K + T T+ T P P KEP + P Sbjct: 216 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 275 Query: 1211 TEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPT--- 1267 T A +P ++P P++P P T T +P A T P +PT Sbjct: 276 TTIKSAPTTPKEPAPTTTKSAP--TTPKEPAP----TTTKEP----APTTPKEPAPTTTK 325 Query: 1268 -PGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGC 1326 P + P + P K P P E P+ T +P+ + K Sbjct: 326 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE-------PAPTTPKEPTPTTPK------ 372 Query: 1327 DPAGFNRDPL------GVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP 1380 +PA ++P P A K P P ++P PK+ A +E P AP Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAP-TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431 Query: 1381 PASSSCLCQDGEDAGSLEPQLPR-----SPPGTAETEPGRAASPPTLESSSLFPDLPVDR 1435 + S E A + P SP T E P P P P + Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491 Query: 1436 FDPPLYGSLSANRDSGLPFACADP----PQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLS 1491 P +P P++T P+ P + E+++P P P + Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPT 550 Query: 1492 GGKVLSKTCPPERTVVPGAAPS 1513 + L+ T P E T P+ Sbjct: 551 TPEELAPTTPEEPTPTTPEEPA 572 Score = 51.2 bits (121), Expect = 2e-05 Identities = 65/244 (26%), Positives = 94/244 (38%), Gaps = 38/244 (15%) Query: 3659 STPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGG 3718 ST K +++ + +LA ++ KP TPKA+ +P+ T T Sbjct: 204 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP-TPKAETTTKGPALTTPKEPTPT-- 260 Query: 3719 GSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLG 3778 + +PAS + T TT + PAP + A + K P + P + Sbjct: 261 -TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS---APTTPKEPAPTTTKEPAPTT- 315 Query: 3779 PKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPTKPK 3835 PKE ++TK P P ++S AP+ P +P P TP+K A TP PT PK Sbjct: 316 PKEPAPTTTKE-----PAPTTTKS------APTTPKEPAPTTPKKPAPTTPKEPAPTTPK 364 Query: 3836 ---PNSQNKPRP---PPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPA 3889 P + +P P P+ EP T K +P PK EPA Sbjct: 365 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK----------KPAPTTPKEPAPTTPKEPA 414 Query: 3890 EPHT 3893 T Sbjct: 415 PTTT 418 Score = 46.6 bits (109), Expect = 5e-04 Identities = 80/372 (21%), Positives = 115/372 (30%), Gaps = 45/372 (12%) Query: 365 PRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPD 424 P P +++ K P+ P + + P S+ P+ P A P P Sbjct: 238 PTPKAETTTKGPALTTPKEPTPT-----TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT 292 Query: 425 TELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPW 484 T+ +AP P P T P PT P P T +P+P P + P Sbjct: 293 TK-SAPTTPKEPAPTT---TKEPAPTTPKEPAPTTTK-----EPAPTTTKSAPTTPKEPA 343 Query: 485 PQV----LPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPRE-KLPAVRS 539 P PT P + P P E ++ T K P P K PA + Sbjct: 344 PTTPKKPAPTTPKEP--APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401 Query: 540 SQGGSPALFTYNGMT---DPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSP 596 + +P T +P S T P P ++P+ PSP Sbjct: 402 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 461 Query: 597 ATNTAGSTCSSLSPMSSSPANPSSEESQLPGPL-----GPSAFFHP---------PTHPQ 642 T + + P ++P P+ + P P P+ P PT P+ Sbjct: 462 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 521 Query: 643 ETGSPFP---SPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGR 699 ET P +P P L +PA P E E P P + Sbjct: 522 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP----APTTPK 577 Query: 700 GGLQGFPRAPPP 711 P+ P P Sbjct: 578 AAAPNTPKEPAP 589 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 86.3 bits (212), Expect = 6e-16 Identities = 137/619 (22%), Positives = 202/619 (32%), Gaps = 95/619 (15%) Query: 1969 TANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPT- 2027 T + P P T + K+A T P E A K +A + +E PT Sbjct: 305 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK-----SAPTTPKEPAPTT 359 Query: 2028 ---PSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAA 2084 P+P +P + A + + S TP+ + KP T PAP+ Sbjct: 360 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK--- 416 Query: 2085 CAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAW 2144 P+PT+ P P +E T+P P +P P P++ Sbjct: 417 -EPTPTT----PKEPAPTTKEPAPTTPKE-------PAPTAPKKPAPTTPKEP------- 457 Query: 2145 APLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGS 2204 AP + TT + +P P TT + +P P + Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTT----------------KSAPTTTKEPAPTTT 501 Query: 2205 VSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTP 2264 SA T TPK+ + P +++ T+P +P T P Sbjct: 502 KSAPT------TPKEPS---PTTTKEP-------APTTPKEPAPTTPKKPAPTTPKEPAP 545 Query: 2265 TGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEP 2324 T + A P P + P T P +P+ +L PT P Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTP-------KETAPTTPKKL----------TPTTP 588 Query: 2325 PTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPS 2384 L P+ PA E + PE+P TP T A P+ P+T TT Sbjct: 589 EKLAPTTPEKPAPTTPE-ELAPTTPEEP-TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646 Query: 2385 STASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPV 2444 + + +P + + + TP+G P LK+ + KKPA E + P Sbjct: 647 PAPTTPKEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS-T 703 Query: 2445 TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPL---EPLAQKCQPPRKK 2501 TC+ A + G + K P P P EP+P P EP + P K Sbjct: 704 TCDKPAPTTPKGTAPTTPK----EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 759 Query: 2502 SHRVSGKERPNHSRGDPSHVTQP---PPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVK 2558 + + P + D T P P + P P P PT EV Sbjct: 760 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 819 Query: 2559 TPASKPRPDQAREDELHPK 2577 T +P DE P+ Sbjct: 820 TTTKEPTTIHKSPDESTPE 838 Score = 85.5 bits (210), Expect = 9e-16 Identities = 140/645 (21%), Positives = 210/645 (32%), Gaps = 128/645 (19%) Query: 873 PSGPRGPSSGHPLK------SKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKT 926 P+ P+ P+S P + A TP+ AP +A P+ P P PA PK Sbjct: 311 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 370 Query: 927 RSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL 986 APT P+ + K + P++ Sbjct: 371 P----APTTTKEPAPTTTKSAPTTPK---------------------EPAPTTPKK---- 401 Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046 P P P+ AP + +P P P+ P T P P K Sbjct: 402 -----PAPTTPKEPAPTTPKEPTPTTPKE---PAPTTKEPAPTTPKEPAPTAPKKPAPTT 453 Query: 1047 GKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKE-VELTQGPRED 1105 KE ++ + ++E P+ P + KE T Sbjct: 454 PKEPAPTTPKE-------PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506 Query: 1106 EPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCAD 1165 P++P +E AP P+EP + P + P P T +E P Sbjct: 507 TPKEPSPTTTKEP----APTTPKEPAPTTP---KKPAPTTPKEPAPT--TPKEPAPTTTK 557 Query: 1166 RPS-VAPKDPLQ--------------VPTNTETSEETRPSLDFPQEAKE--PETAEESAP 1208 +P+ PK+P PT E T P P +E P T EE P Sbjct: 558 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617 Query: 1209 DSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTP 1268 + E E + P A A P P++P P+ P A T P G++PT Sbjct: 618 TTPE--EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 675 Query: 1269 GVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVA--NPSSTACPKPSVLSSKISSFGC 1326 + P K P ++ LAP P+ST C KP+ + K ++ Sbjct: 676 -----------LKEPAPTTPKKPAPKE----LAPTTTKEPTSTTCDKPAPTTPKGTA--- 717 Query: 1327 DPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHP----KPSARDAPPA 1382 P K P P ++P PK A L+E P KP+ ++ P Sbjct: 718 ------------PTTPKEPAP-TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 764 Query: 1383 SSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYG 1442 ++ G + + + P +P TA T P A + + P+ P PP Sbjct: 765 TTK-----GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP-----PPTTS 814 Query: 1443 SLSANRDSGLPFACADPPQKTVP--SDPPYPSFLLLEEVSPMLPS 1485 +S + P P ++ P S P P L P +P+ Sbjct: 815 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 859 Score = 78.6 bits (192), Expect = 1e-13 Identities = 144/656 (21%), Positives = 220/656 (33%), Gaps = 116/656 (17%) Query: 992 PRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELI 1051 P P + AP + +PAP + A P T+S+ P K+ A Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKSAPTTPKEPAPTTPKKPA---------- 403 Query: 1052 LKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPR 1111 + +E P+ P + KE T P+E P P+ Sbjct: 404 ---------------PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT-PKEPAPTAPK 447 Query: 1112 KAARQEAGGDGAPANPEEPGGS---RPGPGRSPQARGPSRSLETGAAAREGGPKCADRPS 1168 K A + AP P+EP + P P +P+ P+ + +E P Sbjct: 448 KPA-PTTPKEPAPTTPKEPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505 Query: 1169 VAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEM 1228 PK+P PT T+ T P KEP P T E + P A Sbjct: 506 TTPKEP--SPTTTKEPAPTTP--------KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555 Query: 1229 GASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNS 1288 P P++P P+ TPK + A T P +PT T ++ + Sbjct: 556 TKKPAPTTPKEPAPT-----TPKET---APTTPKKLTPT------------TPEKLAPTT 595 Query: 1289 KDPPARQPGEFLAPVA----NPSSTACPKPSVLSSKISSFGCDPAGFN-RDPLGVPVAKK 1343 + PA E LAP P++ P P+ + + +PA ++P P K Sbjct: 596 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPK 653 Query: 1344 GPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP----------PASSSCLCQDGED 1393 P P ++P PK A L+E P + AP P S++C Sbjct: 654 EPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 712 Query: 1394 AGSLEPQLPRSPPGTAETEPG----RAASPPTL-ESSSLFPDLPVDRFDPP--LYGSLSA 1446 P P+ P T EP + +P TL E + P P + P G S Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 772 Query: 1447 NRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTV 1506 D P P++T P+ P P+ ++ +P P P + +V + T E T Sbjct: 773 TSDKPAP----TTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTT 827 Query: 1507 VPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESV 1566 + H S DE + L+ S G P A + Sbjct: 828 I--------------------HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT- 866 Query: 1567 GRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAV 1622 + E+ T + + R + T E T +A +T+ +T + AT V Sbjct: 867 -KPEMTTTAKDKTTERDLRTT--PETTTAAPKMTKETATTTEKTTESKITATTTQV 919 Score = 73.2 bits (178), Expect = 5e-12 Identities = 111/481 (23%), Positives = 167/481 (34%), Gaps = 71/481 (14%) Query: 10 PPPTMTGDLQPRQVASSPGHPSQP---------PLEDNTPATRTTKG------------A 48 P PT T + P S+P P +P P PA T K Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 430 Query: 49 REAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRL 108 +E P A + A +P + P+ T K SP TP +P S Sbjct: 431 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490 Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168 E +P ++++ PT TP+ P + P TP+ P P +P P Sbjct: 491 TTTKEPAP--------TTTKSAPT---TPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PT 538 Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSY-PEY 227 T +PA +EP T+T +P+ TP+ PAP P+ T+P P P Sbjct: 539 TPKEPAPTTP------KEPAP--TTTKKPAPT-TPKEPAPTTPKE--TAPTTPKKLTPTT 587 Query: 228 QASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287 A + P + P P EP P +P+ + P +P Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647 Query: 288 FPADVAGHAFTNGPLVFAFHQPQGAWP---EEAVGTGPAYPLPTQPAPS----------- 333 P A T P A P+G P +E T P P P + AP+ Sbjct: 648 APTTPKEPAPTT-PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 706 Query: 334 -PLPCYQGQPGGLNRHSDLSGALSSP-GAAHSAPRPFSDSLHKSLTKILPERPPSAQDGL 391 P P P G + A ++P A + P+ + + K P++P + Sbjct: 707 KPAPT---TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 763 Query: 392 GSTRGPPSSLPQRHFPGQAYRASGVDTSP-GPPDTELAAPGPPPARLPQLWDPTAAPYPT 450 +T+GP S+ + P + +T+P P + P P P+ PT + T Sbjct: 764 TTTKGPTSTTSDKPAP-----TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818 Query: 451 P 451 P Sbjct: 819 P 819 Score = 71.6 bits (174), Expect = 1e-11 Identities = 123/549 (22%), Positives = 176/549 (32%), Gaps = 65/549 (11%) Query: 152 TPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPP 211 T +GP P P P T +PA+ P T T S TP+ PAP Sbjct: 297 TTKGPALTTPKEP-TPTTPKEPASTT----------PKEPTPTTIKSAPTTPKEPAPTTT 345 Query: 212 QSRGTSPLQPGSYPEYQASGADSWPPA---AENSFPGANFGVPPAEPEPIPKGSRPGGSP 268 +S T+P +P + + PA + P P EP P + P Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK---KP 402 Query: 269 RGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPT 328 + + P P T P + A +P P+E T P P PT Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPAP----------TTKEPAPTTPKEPAPTAPKKPAPT 452 Query: 329 QP-APSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSA 387 P P+P + P S + +P SAP + + TK P P Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTP--K 509 Query: 388 QDGLGSTRGPPSSLPQRHFPGQAYR---------ASGVDTSPGPPDTELAAPGPPPARLP 438 + +T+ P + P+ P + A P P T+ AP P P Sbjct: 510 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569 Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGM 498 TA PT P T P + AP + PT P Sbjct: 570 TTPKETA---PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 626 Query: 499 EMLSRLPFPAGGPEWQGGSQGALGTAGKTPGP-REKLPAVRSSQGGSPALFTYNGMTDP- 556 + P P + A T K P P K A + +G +P T P Sbjct: 627 TPKAAAPNTPKEPAPTTPKEPA-PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685 Query: 557 -----------GAQPLFFGVAQP-QVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGST 604 +P +P +P GT P +P E P P+ TA +T Sbjct: 686 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE-PAPTTPKGTAPTT 744 Query: 605 CSSLSPMSSSPANPSSEE---SQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHY 661 P ++P P+ +E + GP ++ PT P+ET +P EP + P Sbjct: 745 LK--EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKP 801 Query: 662 QPEPAKAFP 670 P + P Sbjct: 802 APTTPETPP 810 Score = 71.2 bits (173), Expect = 2e-11 Identities = 111/492 (22%), Positives = 175/492 (35%), Gaps = 60/492 (12%) Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPP--PRGSSPILSEGSLPALLHLCS 3485 P P + T P + A AP ++ P P+ +P ++ P Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP---K 479 Query: 3486 EVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDG 3545 E AP+TTK P T + P P+ + P P P + + Sbjct: 480 EPAPTTTKSAPTTTKEPA------------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527 Query: 3546 ALERPENEA--SPGSPGPLL-QQALPLGASLPRPGARGQDAEG---KRAPLVFSGKRRAP 3599 A P+ A +P P P ++ P P P + A + AP + K+ P Sbjct: 528 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT--TPKKLTP 585 Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAS 3659 + AP ++ E+ ++ E T + + T P ++ A + Sbjct: 586 TTPEKLAPTTPEKPAPTTPEELAPTT---PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 642 Query: 3660 TPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGG 3719 TP + P P++ + P E A T G P T K +P P++ +P+ T Sbjct: 643 TPKEPA--PTTPKEPAPT-TPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPT--- 695 Query: 3720 SQPQPASGQLQSETATTP--AKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSL 3777 + +P S TTP P+ P + PAP P+E P G+ Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTT-------------PKEPAPTTPKGTA 741 Query: 3778 GPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPTKP 3834 K + T KK P P + G + DKP P TP++ A TP PT P Sbjct: 742 PTTLKEPAPTTPKK---PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 798 Query: 3835 KPNSQNKPR-PPPSEQRKAEPGHTQRKDRLGKAFPQGRPLL--RPPKRGTAVHGAEPAEP 3891 K + P PPP+ + P T+ + K+ + P L P + EP P Sbjct: 799 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 858 Query: 3892 HTHRTAEAQSDL 3903 T A + ++ Sbjct: 859 TTKTPAATKPEM 870 Score = 69.3 bits (168), Expect = 7e-11 Identities = 141/699 (20%), Positives = 218/699 (31%), Gaps = 76/699 (10%) Query: 15 TGDLQPRQVASSPG---------HPSQPPLEDN---------------TPATRTTKGARE 50 T Q +V++SP PS PP D T T TT Sbjct: 197 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 256 Query: 51 AGGQAQAMELPEAQPRQARDG-ELKPPS--LRGQAPSSTPGKRGSPQTPPGRSPLQAPSR 107 G+ + E Q + +L P S L P + +G T P P Sbjct: 257 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 316 Query: 108 LAGRAEGSPPQRYILGIASSRTKP------TLDETPENPQLEAAQLPEVDTPQGPGTGAP 161 A P I ++ +P + TP+ P + P TP+ P Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 376 Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEP------------PSSFTSTNYTSPSATPRPPAPG 209 P T++ P + ++P P T T P+ T + PAP Sbjct: 377 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436 Query: 210 PPQSRG-TSPLQPG-SYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGS 267 P+ T+P +P + P+ A P P P EP P S P + Sbjct: 437 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT---TPKEPAPTTTKSAPTTT 493 Query: 268 PRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLP 327 PA + P T P +P P++ T P P P Sbjct: 494 KE--------PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545 Query: 328 TQPA-PSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-P 385 T P P+P + P + + ++P + P+ + + + L PE+P P Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP----TTPKKLTPTTPEKLAPTTPEKPAP 601 Query: 386 SAQDGLGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDP 443 + + L T P + P+ P +A+ +T P T P P + P P Sbjct: 602 TTPEELAPTTPEEPTPTTPEEPAPTTP-KAAAPNTPKEPAPTTPKEPAPTTPKEPA---P 657 Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503 T P T P P + P+ ++ + AP + T P Sbjct: 658 TT-PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716 Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSP---ALFTYNGMTDPGAQP 560 P P + A T T K PA + + +P A T G T + Sbjct: 717 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 776 Query: 561 LFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSS 620 P+ + TP P P +P P T + ST ++ ++ +P Sbjct: 777 P--APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 834 Query: 621 EESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPT 659 +L P A + P P + P+ P T Sbjct: 835 STPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873 Score = 64.7 bits (156), Expect = 2e-09 Identities = 122/535 (22%), Positives = 180/535 (33%), Gaps = 82/535 (15%) Query: 1969 TANQLQPENGVSPGGTDNHASVNASPKTAL-TGPTEGAVLLEKCKGSRAAMSLQEEAEPT 2027 T + P P T +PK T P E A ++ A + +E PT Sbjct: 390 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE-----PAPTTPKEPAPT 444 Query: 2028 ----PSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLA 2083 P+P +P + A + + T + +P K T PAP+ A Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504 Query: 2084 ACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPA 2143 P S P+E T+P + PA + ++P Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKK---------PAPTTPKEP------------ 543 Query: 2144 WAPLEEADGVQATTDTGAEDSPVAPPSLT---TSPCDPKEALAGCLLQGEGSPLEDPSSW 2200 AP + TT A +P P T T+P PK+ + + E P+ Sbjct: 544 -APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 602 Query: 2201 PPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGL 2260 P ++ TP++ T PE+ T+P A +P T Sbjct: 603 TPEELAPT-------TPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPK 645 Query: 2261 SSTPTGDEAQAGRGLPGPDPQS-RGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTA 2319 PT + A P + +G P T + P +P A +E + T Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 705 Query: 2320 VPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPS----TGL 2375 P T +G P +P + T+ KEP P TP+ K P T P L Sbjct: 706 DKPAPTTPKGTAPTTP---KEPAPTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKEL 761 Query: 2376 GLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQW 2435 T P+ST SD +P + + + TP K+ + KKPA T Sbjct: 762 APTTTKGPTSTTSD--KPAPTTPKETAPTTP----------KEPAPTTPKKPAPT----- 804 Query: 2436 KGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEP 2490 + P P T EV + P + HK+ P AEP+P AL P EP Sbjct: 805 TPETP-PPTTSEVSTPTTTKEP-TTIHKS-PDESTPELSAEPTPKAL-ENSPKEP 855 Score = 63.9 bits (154), Expect = 3e-09 Identities = 103/426 (24%), Positives = 150/426 (35%), Gaps = 37/426 (8%) Query: 3486 EVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDG 3545 E AP+TTK P T + P T P+ +E P P+ + PA Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKE----PAPTTPKE-PAPTTTKEPA-------PTTTKS 386 Query: 3546 ALERPENEA--SPGSPGPLL-QQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGAR 3602 A P+ A +P P P ++ P P P + A + P + K AP A Sbjct: 387 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446 Query: 3603 GRCAPDHFQED-HLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTP 3661 + AP +E KE +++ S P+ + + T +++K+ A +T Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK----EPAPTTTKSAPTTTKE-PAPTTT 501 Query: 3662 SKALKFPVHP----RKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717 A P P K P E A T P TPK +P P++ +P TK Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTT-TKKP 559 Query: 3718 GGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSL 3777 + P+ + ETA T K P+ PE+L K P E P Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616 Query: 3778 GPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPT-- 3832 + + T K P AP+ P +P P TP++ A TP PT Sbjct: 617 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 676 Query: 3833 -KPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEP 3891 +P P + KP P + + D+ P+G PK EPA Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG-TAPTTPKEPAPTTPKEPAPT 735 Query: 3892 HTHRTA 3897 TA Sbjct: 736 TPKGTA 741 Score = 59.7 bits (143), Expect = 6e-08 Identities = 91/392 (23%), Positives = 139/392 (35%), Gaps = 28/392 (7%) Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRS--PQARGPSRSLETGAAAREGGPKCADR 1166 KP A G A P+EP + P S P+ P+ +E P Sbjct: 289 KPTPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 347 Query: 1167 PSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP-ETAEESAPDSTEFTEALRSPPAACA 1225 PK+P PT T+ T P P KEP T +SAP + + E + P A Sbjct: 348 APTTPKEP--APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK--EPAPTTPKKPA 403 Query: 1226 GEMGASPGLLIPEQPPPS-----RHDTGTPKPS--GSLANTAPHGSSPTPGVGSLLGGPG 1278 P P++P P+ T P P+ A TAP +PT P Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP---APT 460 Query: 1279 GTQAPVSHNSKDPPARQPGEFLAPVAN---PSSTACPKPSVLSSKISSFGCDPAGFNRDP 1335 + P +K+P P E AP P++T P P+ S ++ ++P Sbjct: 461 TPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 519 Query: 1336 LGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAG 1395 P K P P ++P PK+ A +E P + + AP ++ Sbjct: 520 --APTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576 Query: 1396 SLEPQ--LPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRF-DPPLYGSLSANRDSGL 1452 P+ P +P A T P + A E + P+ P + P + A + Sbjct: 577 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 636 Query: 1453 PFACADPPQKTVPSDPPYPSFLLLEEVSPMLP 1484 P++ P+ P P+ +E +P P Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 668 Score = 58.2 bits (139), Expect = 2e-07 Identities = 161/778 (20%), Positives = 236/778 (30%), Gaps = 126/778 (16%) Query: 568 PQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTC-------SSLSPMSSSPANPSS 620 P+ TP P P + ++P+ P+P T + T ++ P ++P P+ Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 373 Query: 621 EESQLPGPLGPSAFFHPPTHPQETGSPFPSP----EPPHSLPTHYQP----EPAKAFPFP 672 ++ P P + P P T P+P EP + P P EPA P Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433 Query: 673 ADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLT 732 A E A T P + P+ P P T S + + T Sbjct: 434 APTTPKEPA-----PTAPKKPAPTTPKEPAPTTPKEPAPTTTKE---PSPTTPKEPAPTT 485 Query: 733 CRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSP-PAAPRVPADAHAGLL 791 + A ++ + P P P P P+ PA Sbjct: 486 TKSAPTTTKEPAP----------TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 535 Query: 792 SHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGM 851 + A E + P+ P P + KL E L Sbjct: 536 APTTPKEPAPTTPKEPAPTTTKKP-APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 594 Query: 852 EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911 + P EEP+ P P P KA K P P P P TP Sbjct: 595 TPEKPAPTTPEELAPT-TPEEPT-PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652 Query: 912 RPGDRGCPARGRPKTRSLGLAPT--EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGS 969 + P P T G APT + AP+ ++ + K+ S + + + Sbjct: 653 KEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 711 Query: 970 GGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAA---LPEETRSSR 1026 G A P P+ AP + +PAP P+ A L E ++ Sbjct: 712 TPKGTA------------------PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 753 Query: 1027 RRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGR 1086 ++ P P K S ++P P P Sbjct: 754 KKPAPKELAPTTTK--------------------------GPTSTTSDKPAPTTP----- 782 Query: 1087 RGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGG-----SRPGPGRSP 1141 KE T P+E P P+K AP PE P S P + P Sbjct: 783 -------KETAPTT-PKEPAPTTPKKP---------APTTPETPPPTTSEVSTPTTTKEP 825 Query: 1142 QARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPE 1201 S T + E PK + +PK+P VPT T+T T+P + + K E Sbjct: 826 TTIHKSPDESTPELSAEPTPKALEN---SPKEP-GVPT-TKTPAATKPEMTTTAKDKTTE 880 Query: 1202 TAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANT-- 1259 + P++T + A + S Q + TP +L T Sbjct: 881 RDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 940 Query: 1260 APH--GSSPTPGVGSLLGGPGGTQAPVSH--NSKDPPARQPGEFLAPVANPSSTACPK 1313 AP + T ++ P T P NSK + AP P+ST PK Sbjct: 941 APKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP-KKPTSTKKPK 997 Score = 55.8 bits (133), Expect = 8e-07 Identities = 107/521 (20%), Positives = 178/521 (34%), Gaps = 64/521 (12%) Query: 999 TQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQK 1058 T P S+ P P + +T S +R P K P K+K + +E+ + + Sbjct: 70 TSPPSSKKAPPP------SGASQTIKSTTKRSP--KPPNKKKTKKVIESEEITEEHSVSE 121 Query: 1059 NRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEA 1118 N+ +S S + +K+ +V+ + R + P+ EA Sbjct: 122 NQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA 181 Query: 1119 G-----GDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKD 1173 G GD P+ SP+ A+ P+ + P+ Sbjct: 182 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKI----------TTAKPINPRPSLPPNSDTSK 231 Query: 1174 PLQVPTNTETSEETRPSLDFPQE-----------AKEPETAEESAPDSTEFTEALRSPPA 1222 + N ET+ ET+ + ++ AKE ++ E+++ T + + P Sbjct: 232 ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 291 Query: 1223 ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQA 1282 A P L P++P P+ TPK A+T P +PT ++ P + Sbjct: 292 PKAETTTKGPALTTPKEPTPT-----TPKEP---ASTTPKEPTPT----TIKSAPTTPKE 339 Query: 1283 PVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAK 1342 P +K P P+ T +P+ ++K +PA P Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK------EPAPTTTK--SAPTTP 391 Query: 1343 KGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLP 1402 K P P ++P PK+ A +E P AP E A P P Sbjct: 392 KEPAP-TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA----PTAP 446 Query: 1403 RSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQK 1462 + P T EP +++ P P +P + SA + P A K Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKEPAPTTTKSAPTTTKEP---APTTTK 502 Query: 1463 TVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPE 1503 + P+ P PS +E +P P P + K + T P E Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKE-PAPTTPKKPAPTTPKE 542 Score = 55.8 bits (133), Expect = 8e-07 Identities = 140/683 (20%), Positives = 220/683 (32%), Gaps = 121/683 (17%) Query: 2193 PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKE-KLWESPGRATSPPLAGAVSP 2251 P+ S PP S DT K+++L + +++ E K + + TS G Sbjct: 216 PINPRPSLPPNS----------DTSKETSLTVNKETTVETKETTTTNKQTSTD--GKEKT 263 Query: 2252 SVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGH 2311 + A + T D A + L P P++ + +G + +P Sbjct: 264 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKA---------ETTTKGPALTTPKEPTPTTP 314 Query: 2312 REGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCP 2371 +E + T P T++ A T+ KEP P T +S T P+ P Sbjct: 315 KEPASTTPKEPTPTTIKSAP------------TTPKEP----APTTTKSAPTT-PKEPAP 357 Query: 2372 STGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTE 2431 +T T P+ T + +P + + + T + P P K+ + KKPA T Sbjct: 358 TT------TKEPAPTTP--KEPAPTTTKEPAPTTTKSAPTTP---KEPAPTTPKKPAPTT 406 Query: 2432 NGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHR-PHPGAPAEPSPAALPAQQPLEP 2490 + P P P + A + P P P EP+P A P P Sbjct: 407 PKEPAPTTPKEPT------------PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454 Query: 2491 LAQKCQPPR-------KKSHRVSGKE-RPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHS 2542 P+ K+ + KE P ++ P+ +P P +K P P Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT-TKSAPTTPKEPSP 513 Query: 2543 QQLHPPSPTEHEVDVKTPASKPRPDQARED-ELHPKQ----AEKREGRRWRREPTVDSPS 2597 P+PT + T KP P +E PK+ K+ +EP +P Sbjct: 514 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 573 Query: 2598 HSEGKSNKKRGKLRGRRL-----------REESILPVSADVISDGRGSRPSPAMASYAA- 2645 + + KK +L E + P + + + P+P AA Sbjct: 574 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 633 Query: 2646 ----SPSHCLSVEGGPEADGEQPPRL-ATLGPGVMEGAAETDQEALCAGETGAQKPPGDR 2700 P+ E P E P P +G A T + T +KP Sbjct: 634 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE--PAPTTPKKPAPKE 691 Query: 2701 M-----------LCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAED 2749 + C G PT K + P T G + EPA Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 751 Query: 2750 SSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNP----DTQGGVQG 2805 + + + E T GP TS PA +T P P + Sbjct: 752 TPKKPAPKELA----PTTTKGPTS--TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 805 Query: 2806 PEGPTPDAS----GSSAKDPPSL 2824 PE P P S ++ K+P ++ Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTI 828 Score = 51.2 bits (121), Expect = 2e-05 Identities = 65/244 (26%), Positives = 94/244 (38%), Gaps = 38/244 (15%) Query: 3659 STPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGG 3718 ST K +++ + +LA ++ KP TPKA+ +P+ T T Sbjct: 256 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP-TPKAETTTKGPALTTPKEPTPT-- 312 Query: 3719 GSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLG 3778 + +PAS + T TT + PAP + A + K P + P + Sbjct: 313 -TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS---APTTPKEPAPTTTKEPAPTT- 367 Query: 3779 PKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQA--TPSRVLPTKPK 3835 PKE ++TK P P ++S AP+ P +P P TP+K A TP PT PK Sbjct: 368 PKEPAPTTTKE-----PAPTTTKS------APTTPKEPAPTTPKKPAPTTPKEPAPTTPK 416 Query: 3836 ---PNSQNKPRP---PPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPA 3889 P + +P P P+ EP T K +P PK EPA Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK----------KPAPTTPKEPAPTTPKEPA 466 Query: 3890 EPHT 3893 T Sbjct: 467 PTTT 470 Score = 46.6 bits (109), Expect = 5e-04 Identities = 80/372 (21%), Positives = 115/372 (30%), Gaps = 45/372 (12%) Query: 365 PRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPD 424 P P +++ K P+ P + + P S+ P+ P A P P Sbjct: 290 PTPKAETTTKGPALTTPKEPTPT-----TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT 344 Query: 425 TELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPW 484 T+ +AP P P T P PT P P T +P+P P + P Sbjct: 345 TK-SAPTTPKEPAPTT---TKEPAPTTPKEPAPTTTK-----EPAPTTTKSAPTTPKEPA 395 Query: 485 PQV----LPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPRE-KLPAVRS 539 P PT P + P P E ++ T K P P K PA + Sbjct: 396 PTTPKKPAPTTPKEP--APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 453 Query: 540 SQGGSPALFTYNGMT---DPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSP 596 + +P T +P S T P P ++P+ PSP Sbjct: 454 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513 Query: 597 ATNTAGSTCSSLSPMSSSPANPSSEESQLPGPL-----GPSAFFHP---------PTHPQ 642 T + + P ++P P+ + P P P+ P PT P+ Sbjct: 514 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 573 Query: 643 ETGSPFP---SPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGR 699 ET P +P P L +PA P E E P P + Sbjct: 574 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP----APTTPK 629 Query: 700 GGLQGFPRAPPP 711 P+ P P Sbjct: 630 AAAPNTPKEPAP 641 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.131 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 231,127,638 Number of Sequences: 37866 Number of extensions: 16726558 Number of successful extensions: 159907 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1194 Number of HSP's successfully gapped in prelim test: 3016 Number of HSP's that attempted gapping in prelim test: 60303 Number of HSP's gapped (non-prelim): 76336 length of query: 3925 length of database: 18,247,518 effective HSP length: 122 effective length of query: 3803 effective length of database: 13,627,866 effective search space: 51826774398 effective search space used: 51826774398 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.