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Search of human proteins with 188536004
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188536004 zinc finger protein 469 [Homo sapiens]
(3925 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188536004 zinc finger protein 469 [Homo sapiens] 8143 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 143 4e-33
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 115 9e-25
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 107 2e-22
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 107 3e-22
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 105 7e-22
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 103 4e-21
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 103 4e-21
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 102 6e-21
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 102 1e-20
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 101 1e-20
gi|91208420 bassoon protein [Homo sapiens] 99 6e-20
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 99 1e-19
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 95 2e-18
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 95 2e-18
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 94 2e-18
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 94 3e-18
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 94 3e-18
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 94 3e-18
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 92 1e-17
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 91 2e-17
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 91 2e-17
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 91 2e-17
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 91 3e-17
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 89 7e-17
gi|160707881 formin 2 [Homo sapiens] 88 2e-16
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 88 2e-16
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 86 6e-16
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 86 6e-16
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 86 6e-16
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 8143 bits (21130), Expect = 0.0
Identities = 3925/3925 (100%), Positives = 3925/3925 (100%)
Query: 1 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60
MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL
Sbjct: 1 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60
Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120
PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY
Sbjct: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120
Query: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF 180
ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF
Sbjct: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF 180
Query: 181 HRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAE 240
HRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAE
Sbjct: 181 HRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAE 240
Query: 241 NSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNG 300
NSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNG
Sbjct: 241 NSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNG 300
Query: 301 PLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGA 360
PLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGA
Sbjct: 301 PLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGA 360
Query: 361 AHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP 420
AHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP
Sbjct: 361 AHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP 420
Query: 421 GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSA 480
GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSA
Sbjct: 421 GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSA 480
Query: 481 PLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSS 540
PLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSS
Sbjct: 481 PLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSS 540
Query: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT 600
QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT
Sbjct: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT 600
Query: 601 AGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTH 660
AGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTH
Sbjct: 601 AGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTH 660
Query: 661 YQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLS 720
YQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLS
Sbjct: 661 YQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLS 720
Query: 721 SASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP 780
SASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP
Sbjct: 721 SASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP 780
Query: 781 RVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKL 840
RVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKL
Sbjct: 781 RVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKL 840
Query: 841 DSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPP 900
DSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPP
Sbjct: 841 DSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPP 900
Query: 901 LPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDS 960
LPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDS
Sbjct: 901 LPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDS 960
Query: 961 GGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPE 1020
GGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPE
Sbjct: 961 GGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPE 1020
Query: 1021 ETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG 1080
ETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG
Sbjct: 1021 ETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG 1080
Query: 1081 PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRS 1140
PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRS
Sbjct: 1081 PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRS 1140
Query: 1141 PQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP 1200
PQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP
Sbjct: 1141 PQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP 1200
Query: 1201 ETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTA 1260
ETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTA
Sbjct: 1201 ETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTA 1260
Query: 1261 PHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSK 1320
PHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSK
Sbjct: 1261 PHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSK 1320
Query: 1321 ISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP 1380
ISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP
Sbjct: 1321 ISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAP 1380
Query: 1381 PASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPL 1440
PASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPL
Sbjct: 1381 PASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPL 1440
Query: 1441 YGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTC 1500
YGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTC
Sbjct: 1441 YGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTC 1500
Query: 1501 PPERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPREL 1560
PPERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPREL
Sbjct: 1501 PPERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPREL 1560
Query: 1561 AEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVE 1620
AEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVE
Sbjct: 1561 AEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVE 1620
Query: 1621 AVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLC 1680
AVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLC
Sbjct: 1621 AVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLC 1680
Query: 1681 QAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL 1740
QAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL
Sbjct: 1681 QAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL 1740
Query: 1741 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS 1800
PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS
Sbjct: 1741 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS 1800
Query: 1801 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860
HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH
Sbjct: 1801 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860
Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920
PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG
Sbjct: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920
Query: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS 1980
KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS
Sbjct: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS 1980
Query: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL 2040
PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL
Sbjct: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL 2040
Query: 2041 ALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLG 2100
ALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLG
Sbjct: 2041 ALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLG 2100
Query: 2101 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG 2160
PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG
Sbjct: 2101 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG 2160
Query: 2161 AEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDS 2220
AEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDS
Sbjct: 2161 AEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDS 2220
Query: 2221 TLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDP 2280
TLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDP
Sbjct: 2221 TLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDP 2280
Query: 2281 QSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEG 2340
QSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEG
Sbjct: 2281 QSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEG 2340
Query: 2341 EMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRN 2400
EMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRN
Sbjct: 2341 EMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRN 2400
Query: 2401 ASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLS 2460
ASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLS
Sbjct: 2401 ASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLS 2460
Query: 2461 RHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSH 2520
RHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSH
Sbjct: 2461 RHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSH 2520
Query: 2521 VTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAE 2580
VTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAE
Sbjct: 2521 VTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAE 2580
Query: 2581 KREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAM 2640
KREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAM
Sbjct: 2581 KREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAM 2640
Query: 2641 ASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDR 2700
ASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDR
Sbjct: 2641 ASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDR 2700
Query: 2701 MLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEG 2760
MLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEG
Sbjct: 2701 MLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEG 2760
Query: 2761 VWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKD 2820
VWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKD
Sbjct: 2761 VWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKD 2820
Query: 2821 PPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARL 2880
PPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARL
Sbjct: 2821 PPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARL 2880
Query: 2881 PTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEPSRE 2940
PTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEPSRE
Sbjct: 2881 PTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEPSRE 2940
Query: 2941 AGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPEPPSLERERC 3000
AGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPEPPSLERERC
Sbjct: 2941 AGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPEPPSLERERC 3000
Query: 3001 DGGLPGNTHLLPLRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQ 3060
DGGLPGNTHLLPLRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQ
Sbjct: 3001 DGGLPGNTHLLPLRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQ 3060
Query: 3061 SRRTEEAAGAGRAQGRGRPAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPTCYMC 3120
SRRTEEAAGAGRAQGRGRPAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPTCYMC
Sbjct: 3061 SRRTEEAAGAGRAQGRGRPAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPTCYMC 3120
Query: 3121 VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNEHLREHAVRFARRGQAR 3180
VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNEHLREHAVRFARRGQAR
Sbjct: 3121 VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNEHLREHAVRFARRGQAR 3180
Query: 3181 RSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240
RSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG
Sbjct: 3181 RSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240
Query: 3241 ERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPV 3300
ERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPV
Sbjct: 3241 ERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPV 3300
Query: 3301 HEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAH 3360
HEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAH
Sbjct: 3301 HEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAH 3360
Query: 3361 GLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPF 3420
GLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPF
Sbjct: 3361 GLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPF 3420
Query: 3421 AFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPAL 3480
AFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPAL
Sbjct: 3421 AFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPAL 3480
Query: 3481 LHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGD 3540
LHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGD
Sbjct: 3481 LHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGD 3540
Query: 3541 CALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPG 3600
CALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPG
Sbjct: 3541 CALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPG 3600
Query: 3601 ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAST 3660
ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAST
Sbjct: 3601 ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAST 3660
Query: 3661 PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGS 3720
PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGS
Sbjct: 3661 PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGS 3720
Query: 3721 QPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK 3780
QPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK
Sbjct: 3721 QPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK 3780
Query: 3781 EKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQN 3840
EKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQN
Sbjct: 3781 EKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQN 3840
Query: 3841 KPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAEAQ 3900
KPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAEAQ
Sbjct: 3841 KPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAEAQ 3900
Query: 3901 SDLLSQLFGQRLTGFKIPLKKDASE 3925
SDLLSQLFGQRLTGFKIPLKKDASE
Sbjct: 3901 SDLLSQLFGQRLTGFKIPLKKDASE 3925
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 143 bits (360), Expect = 4e-33
Identities = 273/1060 (25%), Positives = 359/1060 (33%), Gaps = 246/1060 (23%)
Query: 6 PRGAPPPTMTGDLQPRQVASSPGHPSQP-----PLEDNTPATRTTKGAREAGGQAQAMEL 60
P+GAP P+ L P+ V P P P PAT K QA A+ +
Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK-------QAPALSM 913
Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120
+ P++AR P+ +G P+S P +G+P TPP +P PS G A SP
Sbjct: 914 TSSSPKKAR----ATPAPKG-IPAS-PSPKGAP-TPPAATP---PSPKGGPATPSPKW-- 961
Query: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQ----GPGT----GAPLRPGL--PRTE 170
+ T P+ P P + A P TP GP T GAP P + P +
Sbjct: 962 -APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Query: 171 AQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQAS 230
PAA F + PP++ + SP+ATP P P T P G
Sbjct: 1021 GSPAATP--FPKGASTPPAATPPSPKGSPAATPLPKG-APTTPAATLPSPKGGPATPSLK 1077
Query: 231 GADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF-- 288
GA + PPAA P P + P+P + P SP+G P GA T P
Sbjct: 1078 GAPT-PPAATPPSPKGGPATPSPKGAPMPPAATP-PSPKG---GLATPPHKGAPTTPAAT 1132
Query: 289 -PADVAGHAF---TNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGG 344
P+ G A P A P P+ + T P PT PA +P GG
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPPPKGAPTTPAATP----PSPKGG 1185
Query: 345 LNRHSDLSGALSSPGAAHSAPR-PFSDSLHKSLTKILPERPPSAQDGL------GSTRGP 397
L S GA ++P A +P+ + K PPS + GL G+ P
Sbjct: 1186 LATPSP-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244
Query: 398 PSSLPQRHFPGQAYRASGVDTSPG--PPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGP 455
++ P G T P PP + PP P +P P+P GGP
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP---NPAVVTPPSPKGGP 1301
Query: 456 L------AATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEML-SRLPFPA 508
A T P P+ AP P P V P PSP G L + P
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP-PAVTP---PSPKGTPTLPATTPSSK 1357
Query: 509 GGPEWQGGSQGAL---------GTAGKTPGPREKLPAVRSSQGG--SPALF--------- 548
GGP +G G TP ++ PA+ S +G SPA+
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
Query: 549 -----------TYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP-------PRVVGASPSE 590
+ +T P P+ A +P G P+ P P V SP E
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Query: 591 SPLP-----------SPATNT--AGSTCSSLSPMSSS--PANPSSEESQL---------- 625
P P +PAT T ++ P S PA PSS +
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 626 -PGPLGPSAFFHPP--THPQETGSP-FPSPE-------------PPHSLPTHYQ--PEPA 666
P L P PP T P +P P+P+ PP P+ Y+ P P
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 667 KAFPFPA--DGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASL 724
+ PA E P P +GP +G P +PP P+ SL +
Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP--ATPAPKGTPTSPPVTPS---SLKDSPT 1652
Query: 725 DQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL------PSPPA 778
V TC+ G + +A G GP L P+P +
Sbjct: 1653 SPASV--TCKM------------------GATVPQASKGLPAKKGPTALKEVLVAPAPES 1692
Query: 779 APRVPADAHAG---LLSHAKTFLLAGDAQAE-GKDDPLRTGFLPSLAATPFPLPASDLDM 834
P + A G S A + + D A+ G PL T P PL D
Sbjct: 1693 TPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST-------VAPAPLLPVQKDS 1745
Query: 835 EDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPE 894
AK G + A P GP P PE
Sbjct: 1746 SKTAK----------GKD----------------ASHSPKGPLAP-------------PE 1766
Query: 895 SKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPT 934
SKA PL AA + P+P A P SL LAP+
Sbjct: 1767 SKASTPLTAAAFEKVLPKPESASVSAAPSPPV-SLPLAPS 1805
Score = 136 bits (342), Expect = 5e-31
Identities = 418/1845 (22%), Positives = 606/1845 (32%), Gaps = 321/1845 (17%)
Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGA 1154
E EL Q P+ + P +A G P P P P P + P +
Sbjct: 13 EQELPQ-PQAETAVLPMSSALSVTAALGQPG-PTLPPPCSPAPQQCPLS----------- 59
Query: 1155 AAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214
AA + P PS PL+VP FPQ + +AP++ F
Sbjct: 60 AANQASP--FPSPSTIASTPLEVP--------------FPQSSSGTALPLGTAPEAPTFL 103
Query: 1215 EALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLA--NTAPHG--------- 1263
L PP + A ASP ++ P GTP S LA APH
Sbjct: 104 PNLIGPPISPAALALASP-MIAPTL-------KGTPSSSAPLALVALAPHSVQKSSAFPP 155
Query: 1264 ---SSPTPGVGSLLGGPGGTQAPVSHNS-KDPPARQPGEFLAPVANPSSTACPKPSVLS- 1318
+SP + G AP++ + K + P E V NP T P P ++S
Sbjct: 156 NLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEV---VPNPKGTPSP-PCIVST 211
Query: 1319 ------SKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHP 1372
+ ++S A + +A PQ + S + + P++ L+
Sbjct: 212 VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271
Query: 1373 KPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLP 1432
P+A S + + AG P +PP P S L P
Sbjct: 272 PPAALSLSTQSLPVVTSSQKTAG------PNTPPDF-----------PISLGSHLAP--- 311
Query: 1433 VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSD---------------PPYPSFLLLE 1477
+GS+ +G P A +DP KT+ D PP PS
Sbjct: 312 ---LHQSSFGSVQLLGQTG-PSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPS---RN 364
Query: 1478 EVSPMLPSHFP------DLSGGKVLSKTCPPERTVVPGAAPSLPGKGSGCSVALMSHLSE 1531
EV P + FP D + S TC P ++ + SL + +L+ S
Sbjct: 365 EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL-----SPTTSLILKSSP 419
Query: 1532 DELEIQKLVTELE-SQLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPH 1590
+ LV ++ S + + P +A A + E+ T PP ++ P
Sbjct: 420 NATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT-TFEVATCVSPP------MSSGPI 472
Query: 1591 EDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQED 1650
+ + V A +E + VAT + P P P + Q+D
Sbjct: 473 SNIEPTSPAALVMAPVAPKE-PSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKD 531
Query: 1651 L------VSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQ 1704
L + GAPFSP A K + L QA + P P P+
Sbjct: 532 LQTVPASLEGAPFSPAQAGL----TTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPE 587
Query: 1705 LDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPA 1764
+LAK S + L K ASS S L + A G
Sbjct: 588 ---ATLAKKSLGEPLPIGK---PASSMTSP-----LGVNSSASVIKTDSYAGPDSAGPLL 636
Query: 1765 PEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGF 1824
+ +P V A PL++ P G +P+ A G + T P
Sbjct: 637 KSSLITPTV-----------AAFPLESADPAGVAPTTA--------KGTSTYTTTASPFL 677
Query: 1825 EGN-EFAPAG-----ASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPA---LSPPIR 1875
EG AP + T P LVP S C P A L+P I
Sbjct: 678 EGTVSLAPKNHPVKEGTLTTLP------LVPTASENCPVAPSPQNTCAPLATLVLAPEIP 731
Query: 1876 QLQLPGPGV--------AKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPA 1927
+ +P P + K DGI L P A SP K
Sbjct: 732 K-SVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL 790
Query: 1928 QGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS-PGGTDN 1986
SP + V+ P + G +G A+ L PEN +S G D+
Sbjct: 791 ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL-PENSLSFQGSKDS 849
Query: 1987 HASVNA-SPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPS----------PPSP-N 2034
A+ ++ +P + PT AV KG ++L + PTPS P +P
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKG----VTLPPKETPTPSVVNLPFPKEGPATPAP 905
Query: 2035 RESLALALTAAHSRSGSEGRTPE--RASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSA 2092
+++ AL++T++ + P+ AS P P+P G PSP A
Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG---PATPSPKWA 962
Query: 2093 AHMPCSLGPLPREDPLT------------SPSRAQGGLGGQLPASPSCRDPPGPQQLLAC 2140
P + P P+ P T +P +GG PA+PS + P P +
Sbjct: 963 PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG-----PATPSPKGAPTPPAVTPP 1017
Query: 2141 SPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSW 2200
SP +P A+T PP+ T P PK + A L +G+P ++
Sbjct: 1018 SPKGSPAATPFPKGAST----------PPAAT--PPSPKGSPAATPLP-KGAPTTPAATL 1064
Query: 2201 P-PGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA-- 2257
P P A TP +T P + SP A PP A SP +
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAAT---PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 2258 -TGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQA 2316
G +TP GL P P+ P P P+G + P +G
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP-SPKGGLATPPP--------KGAP 1172
Query: 2317 VTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDP--GTPETGRSGATKMPRVTCPSTG 2374
T T P G SP +G T + P P G GA P T PS
Sbjct: 1173 TTPAATPPSPKGGLATPSP---KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Query: 2375 LGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQ 2434
GL T +P + + P +P+G P P +G PA+T
Sbjct: 1230 GGLA-TPSPKGAPTTPAATPP---------SPKGGPATPP-----PKGAPTPPAATPPSL 1274
Query: 2435 WKGQA--PH--GPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLE- 2489
G A PH P V S + GP S K P P A PSP P P +
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG---APTPPAATPPSPKGSPGTPPPKG 1331
Query: 2490 -PLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPP 2548
P PP K P+ S+G P T P +G P + PP
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPS-SKGGP---TTPSSKEGPTPPAATPSHKGGPAMTPP 1387
Query: 2549 SPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRG 2608
SP P+ K P L PK+A +P EG + +G
Sbjct: 1388 SPKRGPA---IPSPKGDPTSPAVIPLSPKKAPA-------------TPVTREGAATPSKG 1431
Query: 2609 KLRGRRLREESILPVSADVISDGRGSRPS-------PAMASYAASPSHCLSVEGGPEADG 2661
L + S+ A G + PS PA+ + +
Sbjct: 1432 DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
Query: 2662 EQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKG 2721
+ P A +G + + + + A + + P + A L P
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA--PKEALI 1549
Query: 2722 ASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPE-TSSS 2780
A P++T A+ KE+ + P+ + + ++ P L P TS S
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609
Query: 2781 PADSTTSSCLQGLPDNPDTQGGVQGPEG-PT-PDASGSSAKDPPS 2823
P ++ T + P +P+ P+G PT P + SS KD P+
Sbjct: 1610 PKEAPTPPAV--TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
Score = 131 bits (329), Expect = 2e-29
Identities = 351/1592 (22%), Positives = 528/1592 (33%), Gaps = 223/1592 (14%)
Query: 1141 PQARGPSRSLE-TGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKE 1199
P + GP ++E T AA P PS L++P + P L P++ K
Sbjct: 466 PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVS--------PPLPDPEDLKN 517
Query: 1200 -PETAEESAPDSTEFTEALRSPPAACAGE--MGASPGLLIPEQPPPSRHDTGTPKPSGSL 1256
P + P + L++ PA+ G A GL + P PK S S
Sbjct: 518 LPSSVLVKFPTQKD----LQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSF 573
Query: 1257 ANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACP---- 1312
+T+ P +L G P+ + + A V S A P
Sbjct: 574 QSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG 633
Query: 1313 ---KPSVLSSKISSFGCDPAGFNRDPLGV-PVAKKGPQPYSSPHSELFLGPKDLAGCFLE 1368
K S+++ +++F + A DP GV P KG Y++ S G LA
Sbjct: 634 PLLKSSLITPTVAAFPLESA----DPAGVAPTTAKGTSTYTTTASPFLEGTVSLA----P 685
Query: 1369 ELHPKPSARDA-----PPASSSCLCQDGEDAGS-------LEPQLPRSPPGT----AETE 1412
+ HP P AS +C L P++P+S P A T
Sbjct: 686 KNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP 745
Query: 1413 PGRAASPPTLESSSLFPDLPVDRFDPP----------LYGSLSANRDSGLPFACA----- 1457
PG +S+L P + P G+L+ DS P +
Sbjct: 746 PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQT 805
Query: 1458 -DPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCP----------PERTV 1506
PP K + P P L VSP+ S P+ S SK P P+
Sbjct: 806 KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865
Query: 1507 VPGAAPSLPGKG-----------SGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRG 1555
P A L KG S ++ Q + S +
Sbjct: 866 TPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP 925
Query: 1556 APRELAEAESVGRVELGTGTEPPSQRRTCQATVPH---EDTFSAADLTRVGESTAHREGA 1612
AP+ + + S PPS + P + + G +T +GA
Sbjct: 926 APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA 985
Query: 1613 ESA-VATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQK 1671
+ AT + +G P P A P A+ P + + + PF P+GA+ P
Sbjct: 986 PTPPAATPPSPKGGPATPSPKGAPTPP---AVTPPSPKGSPAATPF-PKGAST--PPAAT 1039
Query: 1672 AGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQ 1731
+ K P PS + GP A K +P + P + + +
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGP---ATPSLKGAPTPPAATPPSPKGGPAT 1096
Query: 1732 ESEDSLRLLPCEQRGGFLPEPGTADQPHRGAP---------------APEAFGSPAVHLA 1776
S + P P+ G A PH+GAP P G+P A
Sbjct: 1097 PSPKGAPMPPAATPPS--PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154
Query: 1777 PDLAFQGDGA--PPLDA-TWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAG 1833
+ +G A PP A T P PS + G P A P +G P+
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214
Query: 1834 ASSLTAPRGREAWLVPVPSP-ACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGIL 1892
+ T P PSP ++ P PA +PP + GP K
Sbjct: 1215 KGAPTTPAATP------PSPKGGLATPSPKGAPTTPAATPPSPK---GGPATPPPK---- 1261
Query: 1893 GLQELTPAAQSPPRVNPSGLEGG-TVEGGKVACGPA---QGSPGGVQVTTLPAVAGHQLG 1948
A +PP P L+GG K A PA SP G T+ P A
Sbjct: 1262 -------GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314
Query: 1949 LEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLL 2008
G G +G T + P SP GT + S K T P+
Sbjct: 1315 ATPPSPKGSPG-TPPPKGAPTPPAVTPP---SPKGTPTLPATTPSSKGGPTTPS------ 1364
Query: 2009 EKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPL 2068
K + A + + P +PPSP R + + +P++A + + +
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424
Query: 2069 LATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSC 2128
AT PS GDL A +P S P + P+ P T S+ L P SP
Sbjct: 1425 AAT-----PSKGDLTPPAVTPVSLKKAPAT--SAPKGGPATPSSKGDPTLPAVTPPSP-- 1475
Query: 2129 RDPPGPQQL-LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLL 2187
++PP P+Q+ + SP AP A T SP P+ +S DP A L
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
Query: 2188 QGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAG 2247
+ + L + P A+T TP T ++ S A+SPP
Sbjct: 1536 KKTPATLAPKEALIP---PAMTVPSPKKTPAIPT------PKEAPATPSSKEASSPP--- 1583
Query: 2248 AVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTA 2307
AV+PS P+ E + P P+ PP P +G ++ +P T
Sbjct: 1584 AVTPST------YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Query: 2308 RLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPR 2367
T+ P P +L+ + P SPA + +MG + + G P + G T +
Sbjct: 1638 ----------TSPPVTPSSLKDS-PTSPASVTCKMGATVPQ-ASKGLP--AKKGPTALKE 1683
Query: 2368 VTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS--RGYKK 2425
V TAP+ + S S + + GP + +K
Sbjct: 1684 VLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQK 1743
Query: 2426 KPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQ 2485
+ T G+ +P GP+ AS L+ K P P + + + + P
Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPESKAS----TPLTAAAFEKVLPKPESASVSAAPSPPVS 1799
Query: 2486 QPLEPLAQKCQPPRKKSHRVS--------GKERPNHSRGDPSHVTQPPPAQGS---KEVL 2534
PL P PP+++ S K + + P P G + VL
Sbjct: 1800 LPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVL 1859
Query: 2535 RAPGSPHSQQLHPPSPTEHEVDVK----------TPASKPRPDQAREDELHPKQAEKREG 2584
+P S + P+P+ + K + S P ++ + +QA+
Sbjct: 1860 VNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAA 1919
Query: 2585 RRWRREPTVDS-PSHSEGKSNKKRGKLRGRRL 2615
EP + S SE K+ K KL R++
Sbjct: 1920 AEIDEEPVSKAKQSRSEKKARKAMSKLGLRQV 1951
Score = 114 bits (286), Expect = 1e-24
Identities = 378/1660 (22%), Positives = 554/1660 (33%), Gaps = 313/1660 (18%)
Query: 1135 PGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFP 1194
P P R+ + A + + GP + +P L V T+ S T L
Sbjct: 359 PLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLIL--- 415
Query: 1195 QEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQP------PPSRHDTG 1248
+S+P++T + P + +G +P L+ P P + +
Sbjct: 416 ----------KSSPNATYHYPLVAQMPVS---SVGTTP--LVVTNPCTIAAAPTTTFEVA 460
Query: 1249 T----PKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVA 1304
T P SG ++N P +SP V APV+ K+P + PV+
Sbjct: 461 TCVSPPMSSGPISNIEP--TSPAALV----------MAPVA--PKEPSTQVATTLRIPVS 506
Query: 1305 NPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAG 1364
P ++ SS + F +D VP + +G P+S + L KD
Sbjct: 507 PPLPDPEDLKNLPSSVLVKFPTQ-----KDLQTVPASLEGA-PFSPAQAGLTT-KKDPTV 559
Query: 1365 CFLEELHPKPSARDAPPASSSCLCQDGEDA---GSLEPQLPRSPPGTAETEP-------- 1413
L + PK S +SS + E SL LP P ++ T P
Sbjct: 560 LPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSAS 619
Query: 1414 --------GRAASPPTLESSSLFPDL---PVDRFDPPLYGSLSANRDSGLPFACADPPQK 1462
G ++ P L+SS + P + P++ DP +A S + +
Sbjct: 620 VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679
Query: 1463 TV---PSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGA-------AP 1512
TV P + P L P++P+ + TC P T+V +P
Sbjct: 680 TVSLAPKNHPVKEGTLT--TLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737
Query: 1513 SLPGKGSGCSVALMSHLSEDEL------EIQKLVTELESQLQRSKDTRGAPRELAEAESV 1566
SLP G+ + +S ++ TE +S + ++G LA++ S
Sbjct: 738 SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE-DSGASATASSKGTLTYLADSPS- 795
Query: 1567 GRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRP 1626
LG P ++R P SA T +G ++ E++ ++ +
Sbjct: 796 ---PLGVSVSPQTKR-------PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ- 844
Query: 1627 GGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDS 1686
G+ PA+ H S P SP+GA P S G+ ++
Sbjct: 845 -GSKDSPATTH---------------SPTPPSPKGAP---TPSAVTPLSPKGVTLPPKET 885
Query: 1687 RPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRG 1746
P V LP P + GP A PK A S S P + R
Sbjct: 886 PTPSVVNLPFPKE--GPATPA--------------PKQAPALSMTSSS------PKKARA 923
Query: 1747 GFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGH 1806
P+ A +GAP P A P+ P +P T P PS
Sbjct: 924 TPAPKGIPASPSPKGAPTPPAATPPSPKGGP-----ATPSPKWAPTPPAATPPSPKGGPA 978
Query: 1807 SAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQ 1866
+ G P A P +G P+ + T P A P P + + P S
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP----AVTPPSPKGSPAATPFPKGAST 1034
Query: 1867 DPALSPPIRQ-----------------LQLPGPGVAKSKDGILGLQELTPAAQSPPRVNP 1909
PA +PP + LP P + + G TP A +PP +P
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP--TPPAATPP--SP 1090
Query: 1910 SGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGT 1969
G GPA SP G + + GL H G A T
Sbjct: 1091 KG-------------GPATPSPKGAPMPPAATPPSPKGGLATPPHKG----APTTPA--- 1130
Query: 1970 ANQLQPENGVSP----GGTDNHASVNASPKTALT------GPTEGAVLLEKCKGSRAAMS 2019
A P+ G++ G A+ SPK L PT A KG A S
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 2020 LQ-EEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPS 2078
+ P +PPSP + +G A++P K LAT SP +
Sbjct: 1191 PKGAPTTPAATPPSPK---------GGLATPSPKGAPTTPAATPPSPKGGLAT-PSPKGA 1240
Query: 2079 VGDLAACAPSPTSAAHMPCSLG-PLPREDPLTSPSRAQGGLGG---QLPASPSCRDPPGP 2134
AA PSP P G P P P +P +GGL + +P+ PP P
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTP---PAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297
Query: 2135 QQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSL------TTSPCDPK--EALAGCL 2186
+ PA +P + A A T + SP PP +P PK L
Sbjct: 1298 KG----GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 2187 LQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP--- 2243
+G P PSS + A T +H G + P R + G TSP
Sbjct: 1354 PSSKGGPTT-PSSKEGPTPPAATPSHKGGP----AMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 2244 PLAGAVSPSVAVRATGLSSTPTGD---------------EAQAGRGLPGPDPQSRGAP-- 2286
PL+ +P+ V G ++ GD A +G P P S+G P
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT-PSSKGDPTL 1467
Query: 2287 PHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSS 2346
P P P +P A + T P PTL P SP E+ +
Sbjct: 1468 PAVTP---PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK----EVPATP 1520
Query: 2347 KEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTP 2406
DP P T + K P P L P+ T P + + TP
Sbjct: 1521 SSRRDPIAP-TATLLSKKTPATLAPKEAL-----IPPAMTV-------PSPKKTPAIPTP 1567
Query: 2407 QGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARK 2466
+ P P + S P + +KG AP P + A P +
Sbjct: 1568 KEAPATPSSKEASS------PPAVTPSTYKG-AP-SPKELLIPPAVTSPSPKEAPTPPAV 1619
Query: 2467 HRPHPG-APAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVS-GKERPNHSRGDPSHVTQP 2524
P P PA P+P P P+ P + K P S G P S+G P+ +
Sbjct: 1620 TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK--KG 1677
Query: 2525 PPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPR-PDQAREDELHPKQAEKRE 2583
P A KEVL AP + + P+ + + S P PD + K K
Sbjct: 1678 PTAL--KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA------KNGSKGP 1729
Query: 2584 GRRWRREPTV----DSPSHSEGK--SNKKRGKLRGRRLREESILPVSADVISDGRGSRPS 2637
P + DS ++GK S+ +G L + + L +A P
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF-----EKVLPK 1784
Query: 2638 PAMASYAASPSHCLSVEGGPEADGEQPPRLATL--GPGVM 2675
P AS +A+PS +S+ P PP+ L PG++
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLV 1824
Score = 113 bits (282), Expect = 4e-24
Identities = 392/1692 (23%), Positives = 563/1692 (33%), Gaps = 372/1692 (21%)
Query: 22 QVASSPGHPSQPPLED-----NTPATRTTKGAREAGGQAQAMELPEA--QPRQARDGELK 74
QVA++ P PPL D N P++ K + Q L A P QA K
Sbjct: 496 QVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKK 555
Query: 75 PPS---LRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKP 131
P+ L AP ++P + + +P PL + LA ++ G P I ASS T P
Sbjct: 556 DPTVLPLVQAAPKNSPSFQSTSSSP--EIPLSPEATLAKKSLGEPLP--IGKPASSMTSP 611
Query: 132 TLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG---LPRTEAQP--AAEELGFHRCFQE 186
+ +A + + D+ GP + PL P A P +A+ G +
Sbjct: 612 LGVNS-------SASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAK 664
Query: 187 PPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP--PAAENSF- 243
S++T+T T P GT P + +++ P P+ +N+
Sbjct: 665 GTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLP-----LVPTASENCPVAPSPQNTCA 719
Query: 244 PGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLV 303
P A + P P+ +P P+L A T P V G + T+
Sbjct: 720 PLATLVLAPEIPKSVPS-----------------PSLPPAGTPPGTKKVDGISHTSA--- 759
Query: 304 FAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHS 363
P+ + P P + G + + G L+
Sbjct: 760 -------------------LAPVASSPKECPT-----EDSGASATASSKGTLTYLA---D 792
Query: 364 APRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPP 423
+P P S+ +RPP+ + + GP + + P AS + P
Sbjct: 793 SPSPLGVSVSPQT-----KRPPTKK----GSAGPDTPIGNLSSPVSPVEASFL------P 837
Query: 424 DTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCL-PQSAPL 482
+ L+ G + P PTPP G P+P L P+ L
Sbjct: 838 ENSLSFQGSKDS-------PATTHSPTPPSP----------KGAPTPSAVTPLSPKGVTL 880
Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQG-ALGTAGKTPGPREKLPAVRSSQ 541
P P P+P + LPFP GP Q AL +P PA +
Sbjct: 881 P-----PKETPTPS----VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK--- 928
Query: 542 GGSPALFTYNGM-TDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT 600
G PA + G T P A P SP G P+ P P+ P+ +P PSP
Sbjct: 929 -GIPASPSPKGAPTPPAATP---------PSPKGGPATPSPKWAPTPPAATP-PSPKGGP 977
Query: 601 AG-STCSSLSPMSSSPANPSSEESQLPGPLG---PSAFFHPPTHPQETGSPFP--SPEPP 654
A S + +P +++P +P + P P G P A P +PFP + PP
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPAT-PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036
Query: 655 HSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP---PP 711
+ P + PA A P P A P P GP L+G P P PP
Sbjct: 1037 AATPPSPKGSPA-ATPLPKGAPTTPAA-----TLPSPKGGPATP--SLKGAPTPPAATPP 1088
Query: 712 YPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKD-----GHQR 766
P + S + T S LA G A G
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATP-------PSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141
Query: 767 SPGPPGLPSPPAAPRVPADAHAGLLSHAK-----TFLLAGDAQAEGKDDPLRTGFLPSLA 821
+P P G P+ PAA P GL + T + G P G + A
Sbjct: 1142 TPPPKGAPTTPAA--TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
Query: 822 ATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSS 881
ATP P P L A P G +
Sbjct: 1200 ATP-PSPKGGL------------------------------------ATPSPKGAPTTPA 1222
Query: 882 GHPLKSKAGV-TPESKAPPPLPAATPD-----PQTPRPGDRGCPARGRPKTRSLGLA-PT 934
P K G+ TP K P PAATP P TP P P P + GLA P
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282
Query: 935 EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP-R 993
AP+ + GG A G + P G PP
Sbjct: 1283 HKGAPNPA----------VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
Query: 994 PRRPRTQAPGSRADPA-PRVPRAAALPEETRSSRRRRLPPRKDPRKRKA---------RG 1043
P P P + P P ++ T SS+ PP P + RG
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
Query: 1044 -------GAWGKELILKIVQQK---NRLREYDFASESEEDEQPPP-------RGPGFRGR 1086
G ++ + +K + A+ S+ D PP + P
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452
Query: 1087 RG-------RGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGR 1139
+G +G+ P+E P P++ A + APA P P G+ P
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKE--PPAPKQVATSSSPKK-APATPA-PMGAPTLPAV 1508
Query: 1140 SPQARGPSRSLETGAAAREGGPKCADRPS------VAPKDPLQVPTNTETSEETRPSLDF 1193
P + P T ++ R+ A S +APK+ L P T S + P++
Sbjct: 1509 IPSS--PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566
Query: 1194 PQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPG---LLIPEQPPPSRHDTGTP 1250
P+EA +++E++ SPPA +P LLIP
Sbjct: 1567 PKEAPATPSSKEAS-----------SPPAVTPSTYKGAPSPKELLIP---------PAVT 1606
Query: 1251 KPSGSLANTAPHGSSPTPGVGSLLGGPGG--TQAPVSHNS-KDPPARQPG-----EFLAP 1302
PS A T P + P+P G P G T PV+ +S KD P P
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666
Query: 1303 VANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGP--- 1359
A+ A P+ L + + PA P+ +KGPQ S + + P
Sbjct: 1667 QASKGLPAKKGPTALKEVLVA----PAP-ESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721
Query: 1360 -KDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAAS 1418
K+ + L + P P P S G+DA S P+ P +PP + + P AA+
Sbjct: 1722 AKNGSKGPLSTVAPAPL---LPVQKDSSKTAKGKDA-SHSPKGPLAPPESKASTPLTAAA 1777
Query: 1419 ------PPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDP---- 1468
P S S P PV PL S P P Q+ +PS P
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSL---PLAPS---------PVPTLPPKQQFLPSSPGLVL 1825
Query: 1469 PYPSFLLL----EEVSPMLPSHFPDLSGG----KVLSKTCPPERTVVPGAAPSLP----- 1515
PS L +E+ P++P +SGG VL P+ +P PS
Sbjct: 1826 ESPSKPLAPADEDELLPLIPPE--PISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTK 1883
Query: 1516 -GKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELGTG 1574
KGSG E + + V ELE Q T+ A +LA A + +
Sbjct: 1884 NNKGSG-----------TESDSDESVPELEEQDSTQATTQQA--QLAAAAEIDEEPVSKA 1930
Query: 1575 TEPPSQRRTCQA 1586
+ S+++ +A
Sbjct: 1931 KQSRSEKKARKA 1942
Score = 111 bits (278), Expect = 1e-23
Identities = 285/1249 (22%), Positives = 415/1249 (33%), Gaps = 264/1249 (21%)
Query: 1633 PASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKT----GLCQAEGDSRP 1688
PA PG + + ++ SP+ P + +GAS T G DS
Sbjct: 741 PAGTPPGTKKVDGISHTSALAPVASSPKEC-----PTEDSGASATASSKGTLTYLADSPS 795
Query: 1689 PQDVCLPEPSKQP-------GPQLDAGSLAKCSPDQELSF-PKNKEAASSQESEDSLRLL 1740
P V + +K+P GP G+L+ E SF P+N + S Q S+DS
Sbjct: 796 PLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPEN--SLSFQGSKDS---- 849
Query: 1741 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS 1800
P P P +GAP P A L+ +G PP + P +
Sbjct: 850 PATTHSPTPPSP-------KGAPTPSA--------VTPLSPKGVTLPPKETPTPSVVNLP 894
Query: 1801 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860
+G P + APA + + ++P+ A P PA S
Sbjct: 895 FPKEG----------------PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS--- 935
Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920
P PA +PP + GP K TP A +PP +P G
Sbjct: 936 PKGAPTPPAATPPSPK---GGPATPSPK------WAPTPPAATPP--SPKG--------- 975
Query: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS 1980
GPA SP G T PA A P+ G +
Sbjct: 976 ----GPATPSPKGAP--TPPA----------------------------ATPPSPKGGPA 1001
Query: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAE--PTPSPPSPNRESL 2038
SPK A PT AV KGS AA + A P +PPSP
Sbjct: 1002 ----------TPSPKGA---PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 2039 ALAL------TAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSA 2092
A L T A + +G P S G P AT P+P G PSP A
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGG-PATPSLKGAPTPPAAT--PPSPKGGP---ATPSPKGA 1102
Query: 2093 AHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADG 2152
P + P P+ T P + P SP P + +PA P G
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162
Query: 2153 VQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTH 2212
+ GA +P A +P PK LA +G+P P++ PP +
Sbjct: 1163 LATPPPKGAPTTPAA------TPPSPKGGLA--TPSPKGAP-TTPAATPPSPKGGLATPS 1213
Query: 2213 SGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAG 2272
P +P P G +PS G +TP
Sbjct: 1214 PKGAP-----------------TTPAATPPSPKGGLATPS----PKGAPTTPAATPPSPK 1252
Query: 2273 RGLPGPDPQSRGAPPHTNPDRMPRG-----HSSYSPSNTARLGHREGQAVTAVPTEPPTL 2327
G P P+ PP P + G H +G T+ P PT
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312
Query: 2328 QGAGPDSPACLEGEMGTSSKE--PEDPGTPETGRSGATKMPRVT-----CPSTGLGLGRT 2380
A P SP +G GT + P P G +P T P+T
Sbjct: 1313 PAATPPSP---KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369
Query: 2381 TAPSSTASDFQSDS---PQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKG 2437
T P++T S + P R + +P+GDP P + KK PA+ +
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP---KKAPATPVTREGAA 1426
Query: 2438 QAPHGPVT-CEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQ 2496
G +T V S + P S K G PA PS P + P + K +
Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPK--------GGPATPSSKGDPTLPAVTPPSPK-E 1477
Query: 2497 PPRKKSHRVSGKERPNHSRGDPSHVTQPP-PAQGSKEVLRAPGSPHSQQLHPPSPTEHEV 2555
PP K +V+ P + P+ + P PA P +P S++ P +PT +
Sbjct: 1478 PPAPK--QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR-DPIAPTATLL 1534
Query: 2556 DVKTPAS-KPR----------PDQAREDEL-HPKQAEKREGRRWRREPTVDSPSHSEGKS 2603
KTPA+ P+ P + + PK+A + P +PS +G
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP 1594
Query: 2604 NKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQ 2663
+ K E ++P + V S P+P A +P S E GP +
Sbjct: 1595 SPK-----------ELLIPPA--VTSPSPKEAPTPP----AVTPP---SPEKGPATPAPK 1634
Query: 2664 -PPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGE-----QPT 2717
P + P ++ + + C + GA P + L P + AL E P
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTC--KMGATVPQASKGL-PAKKGPTALKEVLVAPAPE 1691
Query: 2718 GQKGASARGFWGPRETKALG----VCKESGSE-------------PAEDSSRAHSRSEEG 2760
+A GP+ K+ +C + ++ P + S++ +G
Sbjct: 1692 STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG 1751
Query: 2761 VWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGP 2809
+ + P GPL PE+ +S T++ + + P++ P P
Sbjct: 1752 K-DASHSPKGPLAPPESKAS--TPLTAAAFEKVLPKPESASVSAAPSPP 1797
Score = 108 bits (270), Expect = 1e-22
Identities = 177/710 (24%), Positives = 242/710 (34%), Gaps = 119/710 (16%)
Query: 6 PRGAP------PPTMTGDLQPRQVASSPGHPSQ-PPLEDNTPATRTTKGAREAGGQAQAM 58
P+GAP PP+ G L +P P+ PP AT + KGA
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT------- 1220
Query: 59 ELPEAQPRQARDGELKPPSLRGQ--APSSTP-GKRGSPQTPPGRSPLQAPSRLAGRAEGS 115
P A P + G L PS +G P++TP +G P TPP P AP+
Sbjct: 1221 --PAATPPSPKGG-LATPSPKGAPTTPAATPPSPKGGPATPP---PKGAPT--------- 1265
Query: 116 PPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAA 175
PP + T P+L P + A P V TP P G P P+ P A
Sbjct: 1266 PP---------AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP--PKGAPTPPA 1314
Query: 176 EELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ------A 229
PPS S P P PPA PP +GT P P + P + +
Sbjct: 1315 AT---------PPSPKGSPGTPPPKGAPTPPAVTPPSPKGT-PTLPATTPSSKGGPTTPS 1364
Query: 230 SGADSWPPAAENSFPGANFGVPPAEPE----PIPKG--SRPGGSPRGVSFQFPFPALHGA 283
S PPAA S G PP+ P PKG + P P P
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424
Query: 284 STKPFPADVAGHAFTNGPL--VFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQ 341
+ P D+ A T L A P+G + P P T P+P P +
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 342 PGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSL 401
SSP A + P P ++ P+ P+ P ++L
Sbjct: 1485 -----------ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533
Query: 402 PQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRS 461
+ P + PP + +P PA +P + A P P A T S
Sbjct: 1534 LSKKTPATLAPKEALI----PPAMTVPSPKKTPA-IPTPKEAPATPSSKEASSPPAVTPS 1588
Query: 462 MFFNGQPSPGQRLCLPQSAPLPWPQVLPTARP-SPHGMEMLSRLPFPAGGPEWQGGSQGA 520
+ G PSP + L +P + P P+ PT +P E P P G P + +
Sbjct: 1589 TY-KGAPSP-KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
Query: 521 LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP 580
L + +P +V G + + G L + P +P TP +
Sbjct: 1647 LKDSPTSPA------SVTCKMGATVPQASKGLPAKKGPTALKEVLVAP--APESTPIITA 1698
Query: 581 PRVVGASPSESPLPSP-------ATNTAGSTCSSLSPMSSSPANPSSEE-------SQLP 626
P G +S SP A N + S+++P P S + S P
Sbjct: 1699 PTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP 1758
Query: 627 -GPLGP----------SAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEP 665
GPL P +A F E+ S +P PP SLP P P
Sbjct: 1759 KGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVP 1808
Score = 89.7 bits (221), Expect = 5e-17
Identities = 295/1336 (22%), Positives = 419/1336 (31%), Gaps = 229/1336 (17%)
Query: 899 PPLPAATPDPQTPRPGDRGCPARGRPKTRSL-GLAPTEADAPSQGRQQRRGKQLKLFRKD 957
P +P + P P P PA P T+ + G++ T A AP + +
Sbjct: 728 PEIPKSVPSPSLP-------PAGTPPGTKKVDGISHTSALAPVASSPKECPTE------- 773
Query: 958 LDSGGAAEGSGSGG-GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADP------AP 1010
DSG +A S G A P LG P+ +RP T+ + D +P
Sbjct: 774 -DSGASATASSKGTLTYLADSPSP-----LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827
Query: 1011 RVP-RAAALPEETRSSRRRRLPPRK--DPRKRKARGGAWGKELILKIVQQKNRLREYDFA 1067
P A+ LPE + S + + P P +G A + + + L +
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG-APTPSAVTPLSPKGVTLPPKETP 886
Query: 1068 SESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANP 1127
+ S + P GP + Q P K AR G PA+P
Sbjct: 887 TPSVVNLPFPKEGPATPAPK------------QAPALSMTSSSPKKARATPAPKGIPASP 934
Query: 1128 EEPGGSRPGPGRSPQARG----PS-RSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTE 1182
G P P +G PS + T AA PK + +PK P T
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK-GGPATPSPKGAPTPPAATP 993
Query: 1183 TSEETRPSLDFPQEAKEPET----AEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPE 1238
S + P+ P+ A P + + +P +T F + +PPAA
Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT-------------- 1039
Query: 1239 QPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGE 1298
PPS P GS A T +PT +L GG P + PPA P
Sbjct: 1040 --PPS--------PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 1299 FLAPVANPSSTACPKPSVLSSKISSFGC---DPAGFNRDPLGVPVAKKG----PQPYSSP 1351
A PS P P + G G P P + KG P P +P
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Query: 1352 HSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAET 1411
+ P G P P PA++ G L P+ P T
Sbjct: 1150 TTPAATPPSPKGGL----ATPPPKGAPTTPAAT-----PPSPKGGLATPSPKGAPTTPAA 1200
Query: 1412 EPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF--ACADPPQKTVPSDPP 1469
P S P P P G L+ G P A P K P+ PP
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259
Query: 1470 YPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPSLPGKGSGCSVALMSHL 1529
+P P L GG PP + A + P G
Sbjct: 1260 PKGAPTPPAATP------PSLKGG----LATPPHKGAPNPAVVTPPSPKGG--------- 1300
Query: 1530 SEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVP 1589
+ +GAP A + + GT PP T A P
Sbjct: 1301 ------------------PATSPPKGAP--TPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 1590 HE----DTFSAADLTRVGEST--AHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAAL 1643
T A + G T + +EG AT + +G P T P P
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT-PSHKGGPAMTPPSPK-----RGPA 1394
Query: 1644 LPCAQEDLVSGA--PFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQP 1701
+P + D S A P SP+ A PV + GA+ ++GD PP + S +
Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKA--PATPVTREGAA----TPSKGDLTPP---AVTPVSLKK 1445
Query: 1702 GPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL--PCEQRGGFLPEPGTADQPH 1759
P A PK A S + + +L + P + + T+ P
Sbjct: 1446 APATSA--------------PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
Query: 1760 RGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGH--LHP 1817
+ P G+P + + + A P P + + ++ A A + P
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 1818 TAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQL 1877
P + P + P +EA P +P +T+ S L PP +
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP----STYKGAPSPKELLIPP--AV 1605
Query: 1878 QLPGPGVAKSKDGIL-GLQELTPAAQSP------PRVNPSGLEGGTVEGGKVACGPAQGS 1930
P P A + + E PA +P P V PS L+ V C
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
Query: 1931 PGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASV 1990
P + LPA G E L+ A ++ TA + T
Sbjct: 1666 PQASK--GLPAKKGPTALKEV-----LVAPAPESTPIITAPTRKGPQTKKSSATSPPICP 1718
Query: 1991 NASPKTALTGP---TEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHS 2047
+ S K GP A LL K S ++ + P +P + LTAA
Sbjct: 1719 DPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF 1778
Query: 2048 RS---GSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAP-SPTSAAHMPCS-LGPL 2102
E + A SP ++ PL SP P++ P SP P L P
Sbjct: 1779 EKVLPKPESASVSAAPSPPVSLPL---APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835
Query: 2103 PRED--PLTSPSRAQGGLGGQ-----LPA---------SPSCRDP-----PGPQQLLACS 2141
++ PL P GG+ Q +P +PS + P G
Sbjct: 1836 DEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSD 1895
Query: 2142 PAWAPLEEADGVQATT 2157
+ LEE D QATT
Sbjct: 1896 ESVPELEEQDSTQATT 1911
Score = 87.0 bits (214), Expect = 3e-16
Identities = 375/1612 (23%), Positives = 528/1612 (32%), Gaps = 311/1612 (19%)
Query: 65 PRQARDGELKPPSLRGQAPSSTPGKRGS------PQTP--PGRSPLQAPSRLAGRAEGSP 116
P + PP+L PS + GS P P P + + PS + +G+P
Sbjct: 144 PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTP 203
Query: 117 PQRYIL----------------GIAS-SRTKPTLDETPENPQLEAAQLPEV-DTPQGPGT 158
I+ G+AS +T PT +PQ++ + V +PQ PG+
Sbjct: 204 SPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGS 263
Query: 159 GAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGT-- 216
+ P P PAA L Q P TS+ T+ TP P P S G+
Sbjct: 264 LSLKGPVSP-----PAALSLST----QSLPV-VTSSQKTAGPNTP----PDFPISLGSHL 309
Query: 217 SPLQPGSYPEYQASGADSWPPA----------AENSFPGANFGVPPAEPEPIPKGSRPGG 266
+PL S+ Q G + P A ++S GA++ + P+P SR
Sbjct: 310 APLHQSSFGSVQLLG-QTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLP--SRNEV 366
Query: 267 SPRGVSFQFPFPA---------LHGASTKPFPADVAGHAFTNGPLVF---------AFHQ 308
P V+ FP A + + P + +F+ P +H
Sbjct: 367 VPATVA-AFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHY 425
Query: 309 PQGA-WPEEAVGTGPAYPL-PTQPAPSPLPCYQ-----GQPGGLNRHSDLSGALSSPGAA 361
P A P +VGT P P A +P ++ P S++ +SP A
Sbjct: 426 PLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEP--TSPAAL 483
Query: 362 HSAP-RPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP 420
AP P S + T +P PP + PSS+ + FP Q D
Sbjct: 484 VMAPVAPKEPSTQVATTLRIPVSPPLPDPE--DLKNLPSSVLVK-FPTQK------DLQT 534
Query: 421 GPPDTELAAPGPPPARLPQLWDPTAAPY--PTPPGGPLAATRSMFFNGQPSPGQRLCLPQ 478
P E A P A L DPT P P P + S SP L
Sbjct: 535 VPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATL---- 590
Query: 479 SAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVR 538
A + LP +P+ S + P G S ++ GP P ++
Sbjct: 591 -AKKSLGEPLPIGKPA-------SSMTSPLGV-----NSSASVIKTDSYAGPDSAGPLLK 637
Query: 539 SSQ-GGSPALFTYNGMTDPGAQPL-------FFGVAQPQVSPHGTPSLPP---------- 580
SS + A F G P + A P + GT SL P
Sbjct: 638 SSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLE--GTVSLAPKNHPVKEGTL 695
Query: 581 ---PRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHP 637
P V AS + PSP +TC+ L+ + +P P S +P P P A P
Sbjct: 696 TTLPLVPTASENCPVAPSPQ-----NTCAPLATLVLAPEIPKS----VPSPSLPPAGTPP 746
Query: 638 PTHPQE----TGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP-- 691
T + T + P P PT A A ++G L ++P P
Sbjct: 747 GTKKVDGISHTSALAPVASSPKECPTEDSGASATA--------SSKGTLTYLADSPSPLG 798
Query: 692 -HEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHR 750
P+ R + A P P + S + ++ A+FL
Sbjct: 799 VSVSPQTKRPPTKK-GSAGPDTPIGNLSSPVSPVE------------------ASFLPEN 839
Query: 751 QFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDD 810
+ G + SP P+PP+ P + LS L +
Sbjct: 840 SL-------SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV-- 890
Query: 811 PLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFAD 870
+ F ATP P A L M + + T A G+ S +P+ +
Sbjct: 891 -VNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP-ASPSPKGAPTPPAATPP 948
Query: 871 EEPSGPRGPS--------SGHPLKSKAG-VTPESKAPPPLPAATPDPQTPRPGDRGCPAR 921
GP PS + P K G TP K P PAATP P +G PA
Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP------PSPKGGPAT 1002
Query: 922 GRPKTRSLGLAPTEADAPSQGRQQRRGKQLKL-FRKDLDSGGAAEGSGSGGGGRASGL-R 979
PK APT P+ +G F K + AA G A+ L +
Sbjct: 1003 PSPKG-----APT---PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054
Query: 980 PRRNDGLGERPPPR-----------PRRPRTQAPGSRADPAPRVPRAAAL-PEETRSSRR 1027
P P+ P P P + PA P+ A + P T S +
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114
Query: 1028 RRL--PPRKDPRKRKA------RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPR 1079
L PP K A +GG L K A + P P+
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGG-------LATPPPKG-------APTTPAATPPSPK 1160
Query: 1080 GPGFRGRRGRGEKRKEVELTQGPR--------EDEPQKPRKAARQEAGG------DGAPA 1125
G G +G P+ + P P GG GAP
Sbjct: 1161 G-GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219
Query: 1126 NPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSE 1185
P S G +P +G + + +GGP P AP P P + +
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP-ATPPPKGAPTPPAATPPSLKGGL 1278
Query: 1186 ETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRH 1245
T P P A + + P +T + +PPAA SPG PPP
Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGP-ATSPPKGAPTPPAATPPSPKGSPG-----TPPPK-- 1330
Query: 1246 DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVAN 1305
G P P ++ +P G+ P + GG P S PPA P P
Sbjct: 1331 --GAPTPP-AVTPPSPKGTPTLP--ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 1306 PSSTACPK--PSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLA 1363
P S PK P++ S K PA P P + ++P S+ L P +
Sbjct: 1386 PPS---PKRGPAIPSPK--GDPTSPAVIPLSPKKAPATPVTREGAATP-SKGDLTPPAVT 1439
Query: 1364 GCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPP-----GTAETEPGRAAS 1418
L++ P SA PA+ S + ++ P P+ PP T+ + A+
Sbjct: 1440 PVSLKKA-PATSAPKGGPATPS--SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Query: 1419 P-----PTL-----ESSSLFPDLPVDRFDP--PLYGSLSANRDSGL-PFACADPPQKTVP 1465
P PTL S P P R DP P LS + L P PP TVP
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 1466 SDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTC----PPERTVVPGAAPS 1513
S P+ +E +P PS S V T P+ ++P A S
Sbjct: 1557 SPKKTPAIPTPKE-APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607
Score = 84.7 bits (208), Expect = 2e-15
Identities = 239/1058 (22%), Positives = 354/1058 (33%), Gaps = 162/1058 (15%)
Query: 1961 AEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKC--KGSRAAM 2018
A+K+ G+ + SP G ++ ASV + A GP LL+ + AA
Sbjct: 591 AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA--GPDSAGPLLKSSLITPTVAAF 648
Query: 2019 SLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPER---ASSPGLNKPLLATGDSP 2075
L E A+P P+ + + TA+ G+ P+ PL+ T
Sbjct: 649 PL-ESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707
Query: 2076 APSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQ 2135
P APSP + P + L E P + PS P+ P PPG +
Sbjct: 708 CP-------VAPSPQNTC-APLATLVLAPEIPKSVPS----------PSLPPAGTPPGTK 749
Query: 2136 QL--LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSP 2193
++ ++ + A AP+ + T D+GA + + +LT P Q + P
Sbjct: 750 KVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
Query: 2194 LEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRK-EKLWESPGRA---TSPPLAGAV 2249
+ S+ P + ++ S +P +++ +PE+S + +SP T P GA
Sbjct: 810 TKKGSAGPDTPIGNLS---SPVSPVEASF-LPENSLSFQGSKDSPATTHSPTPPSPKGAP 865
Query: 2250 SPSVAVRAT--GLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPR-GHSSYSPSNT 2306
+PS + G++ P + LP P + P P + P +S SP
Sbjct: 866 TPSAVTPLSPKGVTLPPKETPTPSVVNLPFP----KEGPATPAPKQAPALSMTSSSPKKA 921
Query: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMP 2366
+G + P PT A P SP + G ++ P+ TP + K
Sbjct: 922 RATPAPKGIPASPSPKGAPTPPAATPPSP-----KGGPATPSPKWAPTPPAATPPSPKGG 976
Query: 2367 RVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTP---QGDPLGPQDLKQRSRGY 2423
T G P S + SP+ TP +G P K S
Sbjct: 977 PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036
Query: 2424 KKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP 2483
P S + P G T AA+ S G + K P P A PSP P
Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTP--AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 2484 AQQPLE--PLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPH 2541
A + P+ PP K G P H + PP +G G+P
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKG----GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT 1150
Query: 2542 SQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEG 2601
+ PPSP + + TP K P PK + +P+
Sbjct: 1151 TPAATPPSP---KGGLATPPPKGAPTTPAATPPSPKGGLATPSPK-------GAPTTPAA 1200
Query: 2602 KSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSP--AMASYAASPSHCLSVEGGPEA 2659
+G L + P + G + PSP A + AA+P P
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260
Query: 2660 DGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQ 2719
G P AT P ++G T GA P ++ P G P G
Sbjct: 1261 KGAPTPPAAT--PPSLKGGLATPPHK------GAPNPA---VVTPPSPKGGPATSPPKGA 1309
Query: 2720 KGASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSS 2779
A P+ + K + + PA TPP P G P +
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAV-----------------TPP-SPKGTP---T 1348
Query: 2780 SPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGG 2839
PA + +S +G P P ++ EGPTP A+ S K P+ + PP
Sbjct: 1349 LPATTPSS---KGGPTTPSSK------EGPTPPAATPSHKGGPA----------MTPP-- 1387
Query: 2840 RLTRKRNPHV---YGKRCEKPVLPL-----PTQPSFEEG-GDPTLG----PARLPTDLSD 2886
+ KR P + G V+PL P P EG P+ G PA P L
Sbjct: 1388 --SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445
Query: 2887 SSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEP--SREAGAE 2944
+ + P G P + G + +P + P +P EP ++
Sbjct: 1446 APA----------TSAPKGGPATPSSKG--DPTLPAVTPPSP------KEPPAPKQVATS 1487
Query: 2945 KLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSS 2982
P P P P L PA PA SS
Sbjct: 1488 SSPKKAPATPAPMGAPTL---PAVIPSSPKEVPATPSS 1522
Score = 77.0 bits (188), Expect = 3e-13
Identities = 122/483 (25%), Positives = 154/483 (31%), Gaps = 66/483 (13%)
Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLP 3478
PF G P A ++ + P K R P P P P+G+ + P
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS----PSPKGAP------TPP 943
Query: 3479 ALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGR 3538
A P + KG P T P T P P P P +P P A
Sbjct: 944 A-------ATPPSPKGGPATPSPKWAP-TPPAATPPSPKGGPATPSPKGAPTPPAATP-- 993
Query: 3539 GDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRA 3598
P + P +P P GA P P +G A F
Sbjct: 994 -----------PSPKGGPATPSPK-------GAPTP-PAVTPPSPKGSPAATPFPKGAST 1034
Query: 3599 PGARGRCAPDHFQEDHLLQKEKEVSSSHMVS--EGGPRGTFHKGSATKPAGCQSSSKDRS 3656
P A +P L K + + + +GGP KG+ T PA S K
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP-GTK 3715
A +P A P+ P S G LA G P TP A P G +P P G
Sbjct: 1095 ATPSPKGA---PMPPAATPPS-PKGGLATPPHKGA-PTTPAATPPSPKGGLATPPPKGAP 1149
Query: 3716 TGGGSQPQPASGQLQSETATTPAK--PSFPSRSPAPERLPARAQAKSCTKGPREAGEQGP 3773
T + P G L AT P K P+ P+ +P P A KG P
Sbjct: 1150 TTPAATPPSPKGGL----ATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATP 1202
Query: 3774 HGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTK 3833
P KG +T KG PA + G A +P P TP + P
Sbjct: 1203 -----PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
Query: 3834 PKPNSQNKP---RPPPSEQRKAEPGHTQRKDR--LGKAFPQGRPLLRPPKRGTAVHGAEP 3888
P P P PP + A P H + + P+G P PPK A P
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
Query: 3889 AEP 3891
P
Sbjct: 1318 PSP 1320
Score = 71.6 bits (174), Expect = 1e-11
Identities = 109/462 (23%), Positives = 153/462 (33%), Gaps = 49/462 (10%)
Query: 3453 GSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSE----VAPSTTKGWPETLERPVDPVTH 3508
G A P + P P ++P +G L H + V P + KG P T P T
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT-SPPKGAPTP 1312
Query: 3509 PIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALP 3568
P P PPP +P P A+ P ++ P +P P
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372
Query: 3569 LGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628
+ G KR P + P +G D + K+ ++ +
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAI-------PSPKG----DPTSPAVIPLSPKKAPATPVT 1421
Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP----------VHPRKAVGSL 3678
EG T KG T PA S K A S P P V P
Sbjct: 1422 REGA--ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479
Query: 3679 APGELARGTENGMKPATPKAKPGPSSQG--SGSPR--PGTKTGGGSQPQPASGQLQSETA 3734
AP ++A + PATP P+ SP+ P T + P + L +T
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Query: 3735 TT--PAKPSFPSRS--PAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRK 3790
T P + P P+P++ PA K P P KG S K
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599
Query: 3791 --KGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSR--VLPT--KPKPNS------ 3838
V P+ E+ P +P+K P TP + TP+ V P+ K P S
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659
Query: 3839 -QNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKR 3879
P S+ A+ G T K+ L P+ P++ P R
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701
Score = 68.2 bits (165), Expect = 2e-10
Identities = 180/753 (23%), Positives = 241/753 (32%), Gaps = 131/753 (17%)
Query: 3206 PAPKHHRGKRSAGKAAGSPG-DPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264
PAPK S A P P +G SP P A + PS G ATP
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP---- 980
Query: 3265 ATALADAGSPGPPRTTPSPSPDPWAG-GEPLLQATPVHEACKDPSRDCHHCGKRFPKPFK 3323
+ G+P PP TP P P G P + P A PS FPK
Sbjct: 981 ----SPKGAPTPPAATP---PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 3324 LQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLYACELCATVM 3383
SP+ P+ P A L G P L+ P +
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPT--TPAATLPSPKGGPATPSLKGAPTPPAATPPSP- 1090
Query: 3384 RIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGA---PGQKARALEG 3440
+GG + +G P A P K
Sbjct: 1091 ------------------------------KGGPATPSPKGAPMPPAATPPSPKGGL--A 1118
Query: 3441 TLPSKRRRVAMPGSAPGP--GEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPET 3498
T P K + P P G PPP+G +P + P+ +A KG P T
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPPSPK---GGLATPPPKGAPTT 1174
Query: 3499 LERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGS 3558
P P G PS + P + + P + G + GA P A+P S
Sbjct: 1175 ---PAATPPSPKGGLATPS--PKGAPTTPAATPPSPKGGLATPSPKGAPTTP--AATPPS 1227
Query: 3559 PGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQK 3618
P L P GA P A +G A G P A P +
Sbjct: 1228 PKGGLATPSPKGAP-TTPAATPPSPKGGPATPPPKGAPTPPAA----TPPSLKGGLATPP 1282
Query: 3619 EKEVSSSHMVS----EGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP--VHPR 3672
K + +V+ +GGP + KG+ T PA S K S + P K P V P
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG-SPGTPPPKGAPTPPAVTPP 1341
Query: 3673 KAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGG-SQPQPASGQLQS 3731
G+ ++ G P TP +K GP+ + P K G + P P G
Sbjct: 1342 SPKGTPTLPATTPSSKGG--PTTPSSKEGPTPPAA---TPSHKGGPAMTPPSPKRG---- 1392
Query: 3732 ETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGP------------ 3779
PA PS +P +P + T RE G L P
Sbjct: 1393 -----PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447
Query: 3780 ---KEKGESSTKRKKGQVPGPARSESVGSFGRAP------SAPDKPPRTPRKQATPS--R 3828
KG +T KG PA + AP S+P K P TP P+
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507
Query: 3829 VLPTKPK-----PNSQNKP-RPPPSEQRKAEPGHTQRKDRL-----GKAFPQGRPLLRPP 3877
V+P+ PK P+S+ P P + K P K+ L P+ P + P
Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Query: 3878 KRGTAVHGAEPAE------PHTHRTAEAQSDLL 3904
K A ++ A P T++ A + +LL
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600
Score = 67.8 bits (164), Expect = 2e-10
Identities = 104/442 (23%), Positives = 139/442 (31%), Gaps = 44/442 (9%)
Query: 3464 PPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP 3523
P S + S L +L +P P+T +RP P G + P + P
Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQT-KRP--PTKKGSAGPDTPIGNLSSP 827
Query: 3524 PPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA 3583
+SP A+ + G+ + P SP P P + P +++ +G
Sbjct: 828 ---VSPVEASFLP-ENSLSFQGSKDSPATTHSPTPPSP---KGAPTPSAVTPLSPKGVTL 880
Query: 3584 EGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVS--EGGPRGTFHKGS 3641
K P P G P Q L + +G P KG+
Sbjct: 881 PPKETPTPSVVNLPFP-KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA 939
Query: 3642 ATKPAGCQSSSKDRSAASTPSKALKFPVH--PRKAVGSLAPGELARGTENGMKPATPKAK 3699
T PA S K A +P A P P G P T P +PK
Sbjct: 940 PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG 999
Query: 3700 PGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAK-PSFPSRSPAPERLPARA-- 3756
P S G+P P T + PA+ +T PA P P SPA LP A
Sbjct: 1000 PATPSP-KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058
Query: 3757 -------QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA 3809
K P G P + P KG +T KG PA +
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT--------- 1109
Query: 3810 PSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQ 3869
P +P TP + P+ T P P + PP + P T + G A P
Sbjct: 1110 PPSPKGGLATPPHKGAPTTPAATPPSP--KGGLATPPPKGAPTTPAATPPSPKGGLATP- 1166
Query: 3870 GRPLLRPPKRGTAVHGAEPAEP 3891
PPK A P P
Sbjct: 1167 ------PPKGAPTTPAATPPSP 1182
Score = 50.4 bits (119), Expect = 3e-05
Identities = 114/494 (23%), Positives = 165/494 (33%), Gaps = 74/494 (14%)
Query: 3464 PPRGSSPILS-EGSLPALLHLCSEVAPSTTKGWPETLERPVDP-VTHPIRGCELPSN--- 3518
PP S PI + E + PA L + + TL PV P + P LPS+
Sbjct: 465 PPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLV 524
Query: 3519 ------HQECPPPSL-----SPFPAALADGRGDCALDGALERPEN----EASPGSPG-PL 3562
+ P SL SP A L + L P+N +++ SP PL
Sbjct: 525 KFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPL 584
Query: 3563 LQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDH---FQEDHLLQKE 3619
+A SL P G+ A +PL + PD + L+
Sbjct: 585 SPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPT 644
Query: 3620 KEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALK------FPVHPRK 3673
G T KG++T + + + + +K P+ P
Sbjct: 645 VAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA 704
Query: 3674 A----VGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGG---------- 3719
+ V A + P PK+ P PS +G+P PGTK G
Sbjct: 705 SENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP-PGTKKVDGISHTSALAPV 763
Query: 3720 -SQPQ--PASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGS 3776
S P+ P S TA++ ++ + SP+P + Q K + P + G GP
Sbjct: 764 ASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK---RPPTKKGSAGPDTP 820
Query: 3777 LGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP-PRTPRKQATPSRVLPTKPK 3835
+G S + P S S +P+ P P +P+ TPS V P PK
Sbjct: 821 IGNLSSPVSPVEASF----LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876
Query: 3836 -----------PNSQNKPRP---PPSEQRKAEPGHTQRKDRLGKA----FPQGRPLLRPP 3877
P+ N P P P + K P + KA P+G P P
Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936
Query: 3878 KRGTAVHGAEPAEP 3891
K A P P
Sbjct: 937 KGAPTPPAATPPSP 950
Score = 50.4 bits (119), Expect = 3e-05
Identities = 142/634 (22%), Positives = 199/634 (31%), Gaps = 123/634 (19%)
Query: 3245 PRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPD----PWAGGEPLLQAT-- 3298
P+ S P GA TP +A T + GSPG P +P+P P G P L AT
Sbjct: 1297 PKGGPATSPPKGAPTPPAA--TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354
Query: 3299 -----PVHEACKD----PSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEH 3349
P + K+ P+ H G P +R A+ SP+ P P V P
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD---PTSPAVIP-- 1409
Query: 3350 GELLAHLGGAHGLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHM 3409
L + TP + ++ A S
Sbjct: 1410 -------------LSPKKAPATP------------VTREGAATPS--------------- 1429
Query: 3410 NKHLRGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSS 3469
+G P A V AP A PS + +P P ++ P P+ +
Sbjct: 1430 ----KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA 1485
Query: 3470 PILSEGSLPAL-----LHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPP 3524
S PA V PS+ K P T DP+ P
Sbjct: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI---------------APT 1530
Query: 3525 PSL--SPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQD 3582
+L PA LA + + A+ P + +P P P A P P A
Sbjct: 1531 ATLLSKKTPATLAP--KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA---- 1584
Query: 3583 AEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSA 3642
P + G AP + P + + + E GP KG+
Sbjct: 1585 ----VTPSTYKG---APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Query: 3643 TKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKP-- 3700
T P SS KD S S S K +A L + + + P++ P
Sbjct: 1638 TSPPVTPSSLKD-SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696
Query: 3701 -GPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAK 3759
P+ +G P TK + P +A +K + +PAP LP + +
Sbjct: 1697 TAPTRKG-----PQTKKSSATSPPIC----PDPSAKNGSKGPLSTVAPAP-LLPVQKDSS 1746
Query: 3760 SCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRT 3819
KG + P G L P E ++ST S APS P P
Sbjct: 1747 KTAKG--KDASHSPKGPLAPPE-SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803
Query: 3820 PRKQAT---PSRVLPTKP--KPNSQNKPRPPPSE 3848
P T + LP+ P S +KP P E
Sbjct: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
Score = 42.7 bits (99), Expect = 0.007
Identities = 89/367 (24%), Positives = 129/367 (35%), Gaps = 48/367 (13%)
Query: 321 GPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKIL 380
GP P P PAP P ++ + SP S P S T +
Sbjct: 42 GPTLPPPCSPAPQQCPL---------SAANQASPFPSPSTIASTPLEVPFPQSSSGTALP 92
Query: 381 PERPPSAQDGLGSTRGPPSSLPQRHF--PGQAYRASGVDTSPGPPDTELAAPGPPPARLP 438
P A L + GPP S P A G +S P L A P +
Sbjct: 93 LGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAP--LALVALAPHSVQKS 150
Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQP-SPGQRLCLPQSAPLPWPQVLPTARPSPHG 497
+ P +PP +A + S+ P +P + P +V+P + +P
Sbjct: 151 SAFPPNL--LTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVP---SEVVPNPKGTPSP 205
Query: 498 MEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL----PAVRSSQGGSPALFTYNGM 553
++S +P+ P Q + + +T P L P V+ + S + N
Sbjct: 206 PCIVSTVPYHCVTP--MASIQSGVASLPQTT-PTTTLAIASPQVKDTTISSVLISPQN-- 260
Query: 554 TDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSS 613
PG+ L V+ P T SLP V S ++ P+ + S S L+P+
Sbjct: 261 --PGSLSLKGPVSPPAALSLSTQSLP----VVTSSQKTAGPNTPPDFPISLGSHLAPLHQ 314
Query: 614 SPANPSSEESQLPGPLGPSAFFHPPTHP-----QETGSPFPSPE---PPHSLPTHYQPEP 665
S S QL G GPSA P TG+ +PS PP LP+ + P
Sbjct: 315 S----SFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPP--LPSRNEVVP 368
Query: 666 AKAFPFP 672
A FP
Sbjct: 369 ATVAAFP 375
Score = 38.5 bits (88), Expect = 0.13
Identities = 36/113 (31%), Positives = 45/113 (39%), Gaps = 8/113 (7%)
Query: 3204 TEPAPKHHRGKRSAGKAAGSPG-DPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPD- 3261
T P+PK S A +P P +G SP A + PS G ATP
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237
Query: 3262 -SASATALADAGSP--GPPRTTPSPSPDPWAGGEPLLQ---ATPVHEACKDPS 3308
A T A SP GP P +P P A P L+ ATP H+ +P+
Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290
Score = 37.4 bits (85), Expect = 0.30
Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 6/52 (11%)
Query: 3233 EAKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPS 3284
+ KDSP P TP +P GA TP ++ T L+ G PP+ TP+PS
Sbjct: 844 QGSKDSPATTHSP----TPPSPKGAPTP--SAVTPLSPKGVTLPPKETPTPS 889
Score = 37.4 bits (85), Expect = 0.30
Identities = 31/105 (29%), Positives = 39/105 (37%), Gaps = 7/105 (6%)
Query: 3204 TEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSA 3263
T P+PK G + G+P P + K SP P+ STP + S
Sbjct: 992 TPPSPK---GGPATPSPKGAPTPP-AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Query: 3264 SATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPVHEACKDPS 3308
+AT L P T PSP P P L+ P A PS
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGP---ATPSLKGAPTPPAATPPS 1089
Score = 33.5 bits (75), Expect = 4.3
Identities = 43/149 (28%), Positives = 47/149 (31%), Gaps = 5/149 (3%)
Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEG--EAKKDSPGE-RAKPRARSTPSNPDGAATPDS 3262
PAPK S KA +P P G SP E A P +R P P
Sbjct: 1479 PAPKQVATSSSPKKAPATPA-PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 3263 ASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCGKRFPKPF 3322
AT P T PSP P ATP + P K P P
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 3323 KLQRHLAVHSPQRVYLCPRCPRVYPEHGE 3351
+L AV SP P P V P E
Sbjct: 1598 ELLIPPAVTSPSPKE-APTPPAVTPPSPE 1625
Score = 33.1 bits (74), Expect = 5.6
Identities = 28/97 (28%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Query: 3204 TEPAPKHHRGKRSAGKAAGSPG-DPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDS 3262
T P+PK S A P P +G SP P A + PS G ATP
Sbjct: 946 TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Query: 3263 ASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299
A A +P P+ +P+ +P P P P
Sbjct: 1006 KGAPT-PPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 115 bits (288), Expect = 9e-25
Identities = 266/1055 (25%), Positives = 337/1055 (31%), Gaps = 244/1055 (23%)
Query: 8 GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATR-TTKGAREAGGQAQAMELPEAQPR 66
G P P M + R + G P P P T K A + P A+ R
Sbjct: 170 GTPSPAMAR--RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Query: 67 QARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIAS 126
+ G L+ P+ R + S+TP + P R +AP+ P Q G+ +
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH--------PSQPKPKGLQA 279
Query: 127 SR----TKPTLDETPENPQLEAAQLPEVDTPQGPGTGA-PLRPGLPRTEAQPAAEELGFH 181
R T P D P L ++ L TP GT A P+ P P A P L
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSGTKARPVPP--PDNAATPLPATL--- 331
Query: 182 RCFQEPPSSFTSTNYTSPSATP---RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPA 238
PPS P ATP PP+P P S T P P + P QA + + PP
Sbjct: 332 -----PPSP--------PLATPLPLAPPSPSAPPSLQTLPSPPATPPS-QAPPSMTTPPM 377
Query: 239 AENSFPGANFGVPPAE-PEPIPKGS-RPGGSPRGVSFQFPFPALHGASTKPFPADVAGHA 296
P + +PP + P + S + SP +S +L ++ P A H+
Sbjct: 378 QA---PPSLQTIPPIQVPHSLTSPSLQAPPSPLALS------SLQATTSLGSPTLQATHS 428
Query: 297 FTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALS 356
F L + Q Q + T P+ P T P PL P + LS A+S
Sbjct: 429 F----LTMSPRQTQASL------TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478
Query: 357 --------------SPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLP 402
S A+HS P S + L PPS Q S PP
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538
Query: 403 QRHFPGQAYRASGVDTSPG----------------------PPDTELAAPGPPPARLPQL 440
P AS T+P PP+T + PPP P L
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598
Query: 441 WDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEM 500
P P+PP PLA P L LP PL P PSP
Sbjct: 599 ASPPLQGLPSPPLSPLATP-------PPQAPPXLALP---PLQAP-------PSPPASPP 641
Query: 501 LSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQP 560
LS L P+ P+ L A +P P P Q
Sbjct: 642 LSPLATPS--PQAPNALAVHLLQAPFSPPP------------------------SPPVQA 675
Query: 561 LFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSS 620
F A P VSP TP P + A P + P PSP PA+P
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSP------------------PASPPM 716
Query: 621 EESQLPGPLGPSAFFHPPTH--PQETGSP--FPSPEPPHSLPTHYQPEPAKAFPFPADGL 676
S P P P PP P SP PS PP +P P + P P L
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 677 GAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQC 736
+ P P P + LQ P P +P SASL + Q
Sbjct: 777 PMSPLAK-----PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 831
Query: 737 DRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKT 796
LAA L Q P PP P+ A R P +S +
Sbjct: 832 P---PVLAAPLL----------------QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872
Query: 797 FLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSD 856
L A A G P P P+S L D A S T +
Sbjct: 873 TL----ALAPGPPPP------------PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
Query: 857 NPEIDSSF-----IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAAT------ 905
PE ++ ++ A + RGP+ + G AP P P AT
Sbjct: 917 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG------APLPWPPATGPGSAD 970
Query: 906 ----------PDPQTPRPG--DRG-CPARGRPKTRSLGLAPTEADAPSQ--------GRQ 944
P+ TP PG D G P K + A + +P Q G
Sbjct: 971 GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 1030
Query: 945 QRRGKQLKLFRKDL--DSGGAAEGSGSGGGGRASG 977
Q Q L R L + GAA GSG G GG G
Sbjct: 1031 QASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 1065
Score = 103 bits (258), Expect = 3e-21
Identities = 277/1118 (24%), Positives = 361/1118 (32%), Gaps = 212/1118 (18%)
Query: 144 AAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATP 203
AA+ P + TP+ PG+ P P P A LG P + + +
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPA-----ALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
Query: 204 RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSR 263
P GP +S GTS P S P ASG P A+N+ PG P + P +R
Sbjct: 73 SAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAKNTSPG-----PVSSPGRASGTTR 125
Query: 264 PGG-SPRGVSFQFPFPALHGAST---KPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG 319
PG +G+ G +T K T+GP P A A G
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAG 184
Query: 320 TGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLS------GALSSPGAAHSAPRPFSDSLH 373
T P P P+ P P +G ++ S+ S A P A RP S SL
Sbjct: 185 TEVGLPRPA-PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 374 KSLTKI-LPERP-PSAQ--------------DGLGSTRGPPSSLPQRH-FPGQAYRASGV 416
S T + P R PSA+ GL + R P + P++ P +S
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 417 DTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT--PPGGPLAATRSMFFNGQPSPGQRL 474
+P P T+ A P PPP D A P P PP PLA + PSP
Sbjct: 304 LATPSPSGTK-ARPVPPP-------DNAATPLPATLPPSPPLATPLPL---APPSPSAPP 352
Query: 475 CLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL 534
L Q+ P P P P+ P + P P Q + P P
Sbjct: 353 SL-QTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
Query: 535 PAVRSSQGGSPAL---FTYNGMTDPGAQPLFFGVAQPQVSPHGTP------SLP--PPRV 583
++ GSP L ++ M+ Q ++P +P +P SLP PP
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ 470
Query: 584 VGASPSESPLPSPATNTAGSTCSSL------SPMSSSPANPSSEESQLPGP---LGPSAF 634
SP+ SPL SP T SSL +P+SS P +S L P P++
Sbjct: 471 TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530
Query: 635 FHPPTH--------PQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLE 686
PP P +T S P P P P P +A P P E
Sbjct: 531 TTPPLENLPSLAPPPLQTASA-PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI-- 587
Query: 687 ETPFPHEGPEVGRGGLQGFP-------RAPPPYPTHHFSL-------SSASLDQLDVLLT 732
TP P P + LQG P PPP +L S + L L T
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647
Query: 733 CRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLP-----SPPAAPRVPADAH 787
+ ++LA L F SP PP P SPPA+P V A
Sbjct: 648 --PSPQAPNALAVHLLQAPF--------------SP-PPSPPVQAPFSPPASPPVSPSA- 689
Query: 788 AGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEA 847
+QA PSLAA P +P S + + +A
Sbjct: 690 ------------TPPSQAP-----------PSLAAPPLQVPPSPPASPPMSPSATPPPQA 726
Query: 848 LNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLK-SKAGVTPESKAPPPLPAATP 906
P + + + V S P PS+ P + P + PP PA+ P
Sbjct: 727 ---------PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Query: 907 DPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEG 966
+P + PA P ++L P A P Q +A
Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPP--ASFPGQA----------------PFSPSASL 819
Query: 967 SGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSR 1026
S P L + PP P P QAP R P P + + P T +
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP--RRPPTPGPDTSVSGPRLTLA-- 875
Query: 1027 RRRLPPRKDPRKRKARGGAWGKELI---LKIVQQKNRLREYDFASESEEDEQPPP----- 1078
P P R G +L LR YD E PPP
Sbjct: 876 --LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 933
Query: 1079 --------RGP----GFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPAN 1126
RGP FRG G L P E +G +
Sbjct: 934 ACHPAAWSRGPAPPLAFRGAPG-------APLPWPPATGPGSADGLCTIYET--EGPESA 984
Query: 1127 PEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCA 1164
PG PGP SP G + GA A PK A
Sbjct: 985 TPAPGALDPGP--SPGTSGGKAAAGAGAGASSRSPKQA 1020
Score = 93.2 bits (230), Expect = 5e-18
Identities = 181/744 (24%), Positives = 241/744 (32%), Gaps = 122/744 (16%)
Query: 3 GERPRGAPPPTMTGDLQPRQVASSPGHPSQPPL---EDNTPATRTTKGAREAGGQAQAME 59
G + R PPP P + SP + PL + P + T + A +QA
Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 60 LPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQR 119
P QA PPSL+ P P SP SPL S A + GSP +
Sbjct: 371 SMTTPPMQA------PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424
Query: 120 Y---ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176
L ++ +T+ +L +P P P + P PL+ L P +
Sbjct: 425 ATHSFLTMSPRQTQASLT-SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSS 482
Query: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236
L H P + +S SP A P PP +S L P P Q A
Sbjct: 483 PLTIH-----PLQALSSLASHSPQA-PLSSLIMPPLETQSS-LAP---PSLQTPPASLTT 532
Query: 237 PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF---PADVA 293
P EN +P P P+ S P +P + P P A P P +
Sbjct: 533 PPLEN--------LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
Query: 294 GHAFTNGPLVF-AFHQPQGAWPEEAVGTGPAYPLPTQPAPSP----LPCYQGQPGGLNRH 348
T P A P P + + + P PL T P +P LP Q P
Sbjct: 585 SSIATPPPQAPPALASP----PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP------ 634
Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPG 408
S + SP A S P + ++H P P Q PP S P P
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPS 693
Query: 409 QA---YRASGVDTSPGPPDTELAAPG--PPPARLPQLWDPTAAPYPTPPGGPLAATRSMF 463
QA A + P PP + +P PPP P L P P+PP P M
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-----PMS 748
Query: 464 FNGQPSP-------GQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGG 516
+ P P L +P S P P + P A+P P L+ P A
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLP-MSPLAKPPPQAPPALATPPLQA-------- 799
Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG-VAQPQVSPHGT 575
P P P + + P A P+ + Q SP +
Sbjct: 800 ----------LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849
Query: 576 PSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFF 635
P+L PR P P P T+ +G + P S S L GP
Sbjct: 850 PTLQAPR-------RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 636 HPPTHPQE--------TGSPFPSPEPPHSL--------------PTHYQPEPAKAFPF-P 672
+ P+E G SP P L P ++ P P+ P
Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962
Query: 673 ADGLGAEGAFQCLEETPFPHEGPE 696
A G G+ + ET EGPE
Sbjct: 963 ATGPGSADGLCTIYET----EGPE 982
Score = 74.7 bits (182), Expect = 2e-12
Identities = 114/407 (28%), Positives = 137/407 (33%), Gaps = 59/407 (14%)
Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-NTPATRTTKGAREAGGQA----- 55
P P PPP L + + P P+ PPL TP+ + QA
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668
Query: 56 -----QAMELPEAQP---RQARDGELKPPSLRG---QAPSSTPGKRGSPQTPPGRSPLQA 104
QA P A P A PPSL Q P S P P +P P QA
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQA 726
Query: 105 PSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRP 164
P LA PP AS P+ P P L AA P + P P P+ P
Sbjct: 727 PPPLAAPPLQVPPS----PPASPPMSPSATPPPRVPPLLAA--PPLQVPPSPPASLPMSP 780
Query: 165 -GLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSAT------PRPPAPGPPQSRG-- 215
P +A PA + PP+SF SPSA+ PP PP
Sbjct: 781 LAKPPPQAPPALATPPL-QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839
Query: 216 -TSPLQPGSYPEYQASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSF 273
P P + P QA P P S P + P P P P SP +
Sbjct: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP------PSRSPSS-TL 892
Query: 274 QFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQ-----GAWPEEAVGTGPAYPL-- 326
P A H +S P ++ G + +GP A P A A GPA PL
Sbjct: 893 SGPDLAGHSSSATSTPEELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950
Query: 327 ---PTQPAPSPLPCYQGQPGGLNRHSDLSG---ALSSPGAAHSAPRP 367
P P P P G GL + G A +PGA P P
Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997
Score = 73.6 bits (179), Expect = 4e-12
Identities = 241/1046 (23%), Positives = 324/1046 (30%), Gaps = 191/1046 (18%)
Query: 877 RGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQ--TPRPGDRGCPARGRPKTRSLGLAPT 934
R P+S P + P +K P P ++P T RPG G + L ++
Sbjct: 88 RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG--------QKGLRISAE 139
Query: 935 EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLG-ERPPPR 993
E A RGK + ++ S GA + G S RR+ G E PR
Sbjct: 140 ETVA--------RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191
Query: 994 PRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILK 1053
P AP +R P PR + + +S P R+R + GG +
Sbjct: 192 P------APSARPRPPTEGPRKSV----SSASEHSTTEPSPAARRRPSAGGGLQRP---- 237
Query: 1054 IVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKA 1113
AS S P P G RG R
Sbjct: 238 -------------ASRSLSSSATPLSSPARSGPSARGTPR-------------------- 264
Query: 1114 ARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKD 1173
APA+P +P R PQ P + P PS
Sbjct: 265 ---------APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 1174 PLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPG 1233
P+ P N T P T S P +T A SP A + + SP
Sbjct: 316 PVPPPDNAATPL--------------PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361
Query: 1234 LLIPEQPPPSR--------------------HDTGTPK----PS----GSLANTAPHGSS 1265
P Q PPS H +P PS SL T GS
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Query: 1266 PTPGVGSLLG-GPGGTQAPVSHNSK---DPPARQPGEFLAPVANPSSTACPKPSVLSSKI 1321
S L P TQA ++ S+ PP P AP++ P+S P + LS +
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP--LQAPLSLPASP--PLQTSLSPAV 477
Query: 1322 SSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFL-EELHPKPSARDAP 1380
S P + +A PQ +P S L + P + L P++ P
Sbjct: 478 SPLS-SPLTIHPLQALSSLASHSPQ---APLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 1381 P----ASSSCLCQDGEDAGSLEPQLPRSP---PGTAETEPGRAASPPTLESSSLF---PD 1430
P S + A P L P P + P +PP SS+ P
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 1431 LPVDRFDPPLYG------SLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLP 1484
P PPL G S A P A PP + PS P P L SP P
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653
Query: 1485 SHFP-DLSGGKVLSKTCPP-ERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTE 1542
+ L PP + P A+P + + S A S L+ L++
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPA 712
Query: 1543 LESQLQRSKDTRGAPRELA------EAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSA 1596
+ AP LA + PP + A P + S
Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772
Query: 1597 ADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAP 1656
+ A A+AT P P P + PG A P A + A
Sbjct: 773 PASLPMSPLAKPPPQAPPALAT------PPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
Query: 1657 FSPRGANFHFQPVQKAGASKTGLCQAEGDSRPP---QDVCLPEP----SKQPGPQLDAGS 1709
P+ P+ + S + RPP D + P + PGP
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886
Query: 1710 LAKCSPDQELSFPK-NKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAF 1768
SP LS P ++S+ + + LR GG P + PA +
Sbjct: 887 ----SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 942
Query: 1769 GSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHA--------AQG-HSAGRAGGHLH--P 1817
G AP LAF+ GAP WP P A +G SA A G L P
Sbjct: 943 GP-----APPLAFR--GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 995
Query: 1818 TAGRPGFEGNEFAPAGASSLTAPRGR 1843
+ G G + A AGASS + + R
Sbjct: 996 SPGTSGGKAAAGAGAGASSRSPKQAR 1021
Score = 71.2 bits (173), Expect = 2e-11
Identities = 269/1144 (23%), Positives = 371/1144 (32%), Gaps = 196/1144 (17%)
Query: 1639 GHAALLPCAQED--LVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQ------ 1690
G AA P A+ L P SPR PV A G A G +
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPP----PPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 1691 DVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLP 1750
+PE + + GP AG+ ++ + + + + A ++ +
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTS---------------- 110
Query: 1751 EPGTADQPHR--GAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSA 1808
PG P R G P G + ++ + A +P +A SA
Sbjct: 111 -PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE---------APKRSAL--SA 158
Query: 1809 GRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDP 1868
G PT G P + A + + PR P PS T R+S
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR-------PAPSARPRPPTEGPRKSVSS 211
Query: 1869 AL-------SPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGK 1921
A SP R+ G G+ + L TP + SP R PS GT +
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLS-SSATPLS-SPARSGPSAR--GTP---R 264
Query: 1922 VACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSP 1981
P+Q P G+Q P V + +A G L + + + +P
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRK--DAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322
Query: 1982 GGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALA 2041
T A++ SP A P A SLQ P +PPS S+
Sbjct: 323 AATPLPATLPPSPPLATPLPLAPP-------SPSAPPSLQTLPSPPATPPSQAPPSMTTP 375
Query: 2042 LTAAHS--RSGSEGRTPERASSPGLNKPLLATGDSPAP-SVGDLAACAP--SPT-SAAHM 2095
A ++ + P +SP L P P+P ++ L A SPT A H
Sbjct: 376 PMQAPPSLQTIPPIQVPHSLTSPSLQAP-------PSPLALSSLQATTSLGSPTLQATHS 428
Query: 2096 PCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEE---ADG 2152
++ P + LTSPSR P P P + SPA +PL
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488
Query: 2153 VQATTDTGAEDSPVAP-PSLTTSPCDPKEALAGCLLQGEGS-----PLED-PSSWPP--G 2203
+QA + A SP AP SL P + + +LA LQ + PLE+ PS PP
Sbjct: 489 LQALSSL-ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547
Query: 2204 SVSAVTCTHSGDTP----------KDSTLRIPEDSRKEKLWESPGRA----TSPPLAGAV 2249
+ SA T +TP S L P + P +A SPPL G
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607
Query: 2250 SPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRG------HSSYSP 2303
SP ++ AT P + P P +P T + P + +SP
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667
Query: 2304 SNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGAT 2363
+ + QA + P PP A P S A P P +P S AT
Sbjct: 668 PPSPPV-----QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-AT 721
Query: 2364 KMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGY 2423
P+ P L PS AS S S + P+ PL Q
Sbjct: 722 PPPQAPPPLAAPPL--QVPPSPPASPPMSPS-------ATPPPRVPPLLAAPPLQVP--- 769
Query: 2424 KKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPS-PAAL 2482
PAS P P P L+ P A PS PA+
Sbjct: 770 PSPPASLPMSPLAKPPPQAP-------------PALAT---------PPLQALPSPPASF 807
Query: 2483 PAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHS 2542
P Q P P A P P + + Q PP+ + L+AP
Sbjct: 808 PGQAPFSPSASLPMSP-------LATPPPQAPPVLAAPLLQVPPSPPASPTLQAP----- 855
Query: 2543 QQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGK 2602
PP+P T S PR A P R P D HS
Sbjct: 856 --RRPPTP-----GPDTSVSGPRLTLALAP--GPPPPPSRSPSSTLSGP--DLAGHSSSA 904
Query: 2603 SNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGE 2662
++ +LRG E S ++ P A+++ P+ L+ G P A
Sbjct: 905 TSTPE-ELRGYDSGPEGGAAASPPPDAELAACHP----AAWSRGPAPPLAFRGAPGAPLP 959
Query: 2663 QPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQ-KG 2721
PP GPG +G + G A PG L PG G + G+ G G
Sbjct: 960 WPP---ATGPGSADGLCTIYE---TEGPESATPAPG--ALDPGPSPGTSGGKAAAGAGAG 1011
Query: 2722 ASAR 2725
AS+R
Sbjct: 1012 ASSR 1015
Score = 68.9 bits (167), Expect = 9e-11
Identities = 105/410 (25%), Positives = 137/410 (33%), Gaps = 79/410 (19%)
Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSP--AP 2077
LQ P PSPP + + S S TP + P L P L SP +P
Sbjct: 661 LQAPFSPPPSPP------VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
Query: 2078 SVGDLAACAP-SPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQ 2136
+ A P +P A P + P P P SPS L A+P + PP P
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
Query: 2137 LLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLED 2196
L SP A+ P APP+L T P LQ SP
Sbjct: 775 SLPMSPL-----------------AKPPPQAPPALATPP-----------LQALPSP--- 803
Query: 2197 PSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP--SVA 2254
P+S+P G P + +P ++P +P L SP S
Sbjct: 804 PASFP------------GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 2255 VRATGLSSTPTGDEAQAGRGL-----PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARL 2309
++A TP D + +G L PGP P +P T GHSS + S L
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911
Query: 2310 -GHREGQAVTAVPTEPPTLQGA---------GPDSPACLEGEMGTSSKEP--EDPGTPE- 2356
G+ G A + PP + A GP P G G P PG+ +
Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971
Query: 2357 -------TGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHR 2399
G AT P P G A + + S SP+ R
Sbjct: 972 LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021
Score = 68.2 bits (165), Expect = 2e-10
Identities = 259/1167 (22%), Positives = 357/1167 (30%), Gaps = 201/1167 (17%)
Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR---GPSRSL-ETGAAAREGGPKCA 1164
K AAR A P PG RP P +P A G + ++ A R GG A
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 1165 DRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAAC 1224
P AP+ PT + + P+ P + E AP + + S P
Sbjct: 69 TIPESAPRAG---PTRSAGTSSRNPASRPPASGRG-----ERAPPAKNTSPGPVSSPGRA 120
Query: 1225 AGEMGASP----GLLIPEQPPPSRHD-TGTPKPSGSLANTAPHGSSPTPGVGS------- 1272
+G P GL I + +R T PK S A S PTPG S
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 1273 -LLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGF 1331
G G P PP P + ++ + S+T +PS + + S G G
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT---EPSPAARRRPSAG---GGL 234
Query: 1332 NRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDG 1391
R P ++ P SSP PSAR P A +
Sbjct: 235 QR-PASRSLSSSAT-PLSSP------------------ARSGPSARGTPRAPA------- 267
Query: 1392 EDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSG 1451
P P+ P G P + +PP +++ L P A R
Sbjct: 268 ------HPSQPK-PKGLQALRPPQV-TPPRKDAAPALGPLSSSPLATPSPSGTKA-RPVP 318
Query: 1452 LPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDL-SGGKVLSKTCPPERTVVPGA 1510
P A P T+P PP + L L SP P L S PP T P
Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378
Query: 1511 AP---------------------SLPGKGSGCSVALMSHLSEDELE-IQKLVTELESQLQ 1548
AP + P + S+ + L L+ +T Q Q
Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
Query: 1549 RSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAH 1608
S + P + L PP Q A P + L + +H
Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
Query: 1609 REGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQP 1668
A + + ++ + P S A+L E+L S AP P
Sbjct: 499 SPQAPLSSLIMPPLETQSS---LAPPSLQTPPASLTTPPLENLPSLAP----------PP 545
Query: 1669 VQKAGAS------KTGLCQAEGD-SRPPQDVCLP---EPSKQPGPQLDAGSLAKCSPDQE 1718
+Q A A +T C A PP + P PS P A P Q
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605
Query: 1719 LSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPD 1778
L P A+ LP Q P + P+P+A + AVHL
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPP--SPPASPPLSPLATPSPQAPNALAVHLL-Q 662
Query: 1779 LAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLT 1838
F +PP+ A + ASP + +A P+ P + P AS
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQA----PPSLAAPPLQVPPSPP--ASPPM 716
Query: 1839 APRGREAWLVPVP---SPACVSNTHPSRRSQDPALSPPIR---QLQLPGPGVAKSKDGIL 1892
+P P P P V + P+ P+ +PP R L P V S L
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 1893 GLQELT-PAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEA 1951
+ L P Q+PP + L+ P PG + ++ L
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQ--------ALPSPPASFPGQAPFSPSASLPMSPLATPP 828
Query: 1952 DGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKC 2011
+L Q+ P SP P T+++GP
Sbjct: 829 PQAPPVLA--------APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP---------- 870
Query: 2012 KGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLAT 2071
R ++L P P PP S L+ S S TPE + P
Sbjct: 871 ---RLTLAL----APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD-SGPEGGA 922
Query: 2072 GDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDP 2131
SP P +LAAC P+ S GP P P +G G LP P+
Sbjct: 923 AASPPPD-AELAACHPAAWSR-------GPAP-------PLAFRGAPGAPLPWPPA---- 963
Query: 2132 PGPQQLLACSPAWAPLEEADGVQATTDT-GAEDSPVAPPSLTTSPCDPKEALAGCLLQGE 2190
GP ADG+ +T G E + AP +L P G
Sbjct: 964 TGP-------------GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA 1010
Query: 2191 GSPLEDP-----SSWPPGSVSAVTCTH 2212
G+ P P G++ A H
Sbjct: 1011 GASSRSPKQARLGELPLGALQASVVQH 1037
Score = 58.5 bits (140), Expect = 1e-07
Identities = 95/375 (25%), Positives = 137/375 (36%), Gaps = 76/375 (20%)
Query: 3523 PPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALP-------LGASLPR 3575
PPP ++P + G +P E + G G + ++ P G S
Sbjct: 35 PPPPVTPAALRVLGAAGAVG-----RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 3576 PGARGQ-DAEGKRAPLVFSGKRRAPG---ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEG 3631
P +R G+RAP K +PG + GR A + L QK +S+ V+
Sbjct: 90 PASRPPASGRGERAP---PAKNTSPGPVSSPGR-ASGTTRPGPLGQKGLRISAEETVA-- 143
Query: 3632 GPRGTFHKGSATK-PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENG 3690
+G AT+ P S+ R S P+ P R++ A GTE G
Sbjct: 144 -------RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS--------RAAGTEVG 188
Query: 3691 MKPATPKAKPGPSSQG------------SGSPRPGTK---TGGGSQPQPASGQLQSETAT 3735
+ P A+P P ++G + P P + + GG +PAS L S
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 3736 -------------TPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEK 3782
TP P+ PS+ P P+ L A + A GP S
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 3783 GESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKP 3842
S TK + VP P ++ + A P P TP A PS P+ P P+ Q P
Sbjct: 308 SPSGTKAR--PVPPP---DNAATPLPATLPPSPPLATPLPLAPPS---PSAP-PSLQTLP 358
Query: 3843 RPPPSEQRKAEPGHT 3857
PP + +A P T
Sbjct: 359 SPPATPPSQAPPSMT 373
Score = 46.6 bits (109), Expect = 5e-04
Identities = 139/611 (22%), Positives = 190/611 (31%), Gaps = 117/611 (19%)
Query: 428 AAPGPPPARLPQLWD--PTAAPYPTPPGGPLAATRSMFFNGQPSPGQR-----------L 474
AA P AR P L P +P P PP P AA R + G + G++
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTP-AALRVLGAAG--AVGRKPLAERAGGIGGA 68
Query: 475 CLPQSAPLPWP-------QVLPTARPSPHGM-----EMLSRLPFPAGGPEWQGGS--QGA 520
+P+SAP P P +RP G + P P P G+ G
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128
Query: 521 LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTD-----PG-----------AQPLFFG 564
LG G E + ++++ + + D PG A G
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 565 VAQPQVSPHGTPSLPPPR--VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEE 622
+ +P S P PR V AS + PSPA S L +S + S+
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 623 SQLPGPLGPSAFFHP--PTHPQE----------------------------TGSPFPSPE 652
P GPSA P P HP + + SP +P
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 653 PPHS--------------LPTHYQPEPAKAFPFP--ADGLGAEGAFQCLEE---TPFPHE 693
P + LP P P A P P A + Q L TP
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368
Query: 694 GPEVGRGGLQGFP--RAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQ 751
P + +Q P + PP H SL+S SL L S + L
Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPH-SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 752 FCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811
+ R SP P +PP +P + A +T L +
Sbjct: 428 SFLTMSPRQTQASLTSPSRPA-STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486
Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871
L SLA+ P S L M SL +L P +++
Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL-------P 539
Query: 872 EPSGPRGPSSGHPLKSKAGVTPESKAP-----PPLPAATPDPQTP----RPGDRGCPARG 922
+ P ++ PL + TP AP PP P TP P+TP P + PA
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 923 RPKTRSLGLAP 933
P + L P
Sbjct: 600 SPPLQGLPSPP 610
Score = 46.6 bits (109), Expect = 5e-04
Identities = 92/369 (24%), Positives = 124/369 (33%), Gaps = 59/369 (15%)
Query: 3416 GRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAP---GPGEDRPPPRGSSPIL 3472
GR+P A R GA ++ G S P S P G GE PP + +SP
Sbjct: 54 GRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP-- 111
Query: 3473 SEGSLPALLHLCSEVAPSTTKGWPETLERPV---DPVTHPIRGCELPSNHQECPPPSLSP 3529
S P + P KG + E V P R ++ P+
Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171
Query: 3530 FPAALADGRGDCALDGALERPENEASPGSP--GP--LLQQALPLGASLPRPGARGQDAEG 3585
A+A + L RP A P P GP + A + P P AR + + G
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 3586 KRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSS---SHMVSEGGPRGTFHKGSA 3642
G + P +R L +SS S + G PR H S
Sbjct: 232 --------GGLQRPASRS-----------LSSSATPLSSPARSGPSARGTPRAPAHP-SQ 271
Query: 3643 TKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGP 3702
KP G Q+ R TP + P A+G L+ LA + P+ KA+P P
Sbjct: 272 PKPKGLQAL---RPPQVTPPRKDAAP-----ALGPLSSSPLATPS-----PSGTKARPVP 318
Query: 3703 SSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFP---SRSPAPERLPARAQAK 3759
+ +P P T P S L + P PS P P+P P
Sbjct: 319 PPDNAATPLPAT--------LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 3760 SCTKGPREA 3768
S T P +A
Sbjct: 371 SMTTPPMQA 379
Score = 42.7 bits (99), Expect = 0.007
Identities = 62/241 (25%), Positives = 88/241 (36%), Gaps = 46/241 (19%)
Query: 3671 PRKAVGSLAPGELARGTENGMKPATPKAK---PGPSS---QGSGSPRPG----------- 3713
P ++ G+ + +R +G P AK PGP S + SG+ RPG
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 3714 --TKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG-PREAGE 3770
T G + P L + + P+ + SPA R R++A G PR A
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR---RSRAAGTEVGLPRPAPS 195
Query: 3771 QGPHGSLGPKEKGESSTKRKKGQVPGPA--RSESVGSFGRAPSAPDKPPRTPRKQATPSR 3828
P K SS P PA R S G + P++ R+ ATP
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-----RSLSSSATPLS 250
Query: 3829 VLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEP 3888
P + P+++ PR P A P + P+G LRPP+ A P
Sbjct: 251 S-PARSGPSARGTPRAP------AHPSQPK---------PKGLQALRPPQVTPPRKDAAP 294
Query: 3889 A 3889
A
Sbjct: 295 A 295
Score = 42.0 bits (97), Expect = 0.012
Identities = 86/334 (25%), Positives = 103/334 (30%), Gaps = 62/334 (18%)
Query: 3452 PGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIR 3511
P + P P PPP + P+ S PA + P P L P V P
Sbjct: 718 PSATPPP--QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV--PPLLAAPPLQVP-PSP 772
Query: 3512 GCELPSNHQECPPPSLSP---------FPAALADGRGDCALDGA-------LERPENEAS 3555
LP + PPP P P+ A G + L P +A
Sbjct: 773 PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832
Query: 3556 PGSPGPLLQ-----QALPLGASLPRPGARGQDAE--GKRAPLVFSGKRRAPGARGRCAPD 3608
P PLLQ A P + RP G D G R L + P +R
Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------ 886
Query: 3609 HFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA----GCQSSSKDRSAASTPSKA 3664
S S +S GP H SAT G S + +AAS P A
Sbjct: 887 --------------SPSSTLS--GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930
Query: 3665 LKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQG------SGSPRPGTKTGG 3718
HP AP RG P P PG S+ G + P T G
Sbjct: 931 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG-SADGLCTIYETEGPESATPAPG 989
Query: 3719 GSQPQPASGQLQSETATTPAKPSFPSRSPAPERL 3752
P P+ G A A SRSP RL
Sbjct: 990 ALDPGPSPG-TSGGKAAAGAGAGASSRSPKQARL 1022
Score = 41.2 bits (95), Expect = 0.020
Identities = 102/467 (21%), Positives = 143/467 (30%), Gaps = 63/467 (13%)
Query: 3418 QPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSL 3477
+P + +R P + A P +A P + PPP ++ L +L
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP-ATL 331
Query: 3478 PALLHLCSEV--APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALA 3535
P L + + AP + P P P T P + + PPSL P
Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP--- 388
Query: 3536 DGRGDCALDGALERPENEASPG---SPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVF 3592
++ P + SP P PL +L SL P + + +P
Sbjct: 389 -----------IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437
Query: 3593 SGKRRAPGARGRCAPDH--FQEDHLLQKEK--EVSSSHMVSEGGPRGTFHKGSATKPAGC 3648
+P PD Q L + S S VS T H A
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497
Query: 3649 QS----------------SSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMK 3692
S SS + TP +L P P + + SLAP L +
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP--PLENLPSLAPPPLQTASAPLTT 555
Query: 3693 P--ATP--------KAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETAT-TPAKPS 3741
P TP +A P P + +P P T + + P A L S P+ P
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLT----TPPPETPSSIATPPPQAPPALASPPLQGLPSPPL 611
Query: 3742 FPSRSPAPERLPARAQAK-SCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARS 3800
P +P P+ P A P + P + P+ + + P
Sbjct: 612 SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
Query: 3801 ESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPS 3847
F S P P TP QA PS P Q P PP S
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL-----QVPPSPPAS 713
Score = 40.8 bits (94), Expect = 0.027
Identities = 56/219 (25%), Positives = 74/219 (33%), Gaps = 23/219 (10%)
Query: 3668 PVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASG 3727
PV P S AP LA P +P A P S + P+ + P A+
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQ--VPPSPPASPPMSPSATPPPQ--------APPPLAAP 733
Query: 3728 QLQSETATTPAKPSFPSRSPAPERLPARAQAK-SCTKGPREAGEQGPHGSLGPKEKGESS 3786
LQ + + P PS +P P P A P + P P+ +
Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793
Query: 3787 TKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPS------RVLPTKPKPNSQN 3840
T + PA F + S P P TP QA P +V P+ P +
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 3841 KPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKR 3879
PR PP+ P + RL A G P PP R
Sbjct: 854 APRRPPT----PGPDTSVSGPRLTLALAPGPP--PPPSR 886
Score = 32.3 bits (72), Expect = 9.5
Identities = 36/129 (27%), Positives = 43/129 (33%), Gaps = 28/129 (21%)
Query: 3193 SSAVAHLLNSITEPAPKHHRG-------KRSAGKAAGSPGDPWGQEGEAKKDSPGERAKP 3245
SSA H S TEP+P R +R A ++ S P + P R P
Sbjct: 210 SSASEH---STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA---RSGPSARGTP 263
Query: 3246 RARSTPS----------NPDGAATPDSASATALADAGS-----PGPPRTTPSPSPDPWAG 3290
RA + PS P P +A AL S P P T P P P
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNA 323
Query: 3291 GEPLLQATP 3299
PL P
Sbjct: 324 ATPLPATLP 332
Score = 32.3 bits (72), Expect = 9.5
Identities = 30/104 (28%), Positives = 35/104 (33%), Gaps = 15/104 (14%)
Query: 3204 TEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSN--------PD 3255
T AP H + G A P +A + P A +PS PD
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 3256 GAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299
AATP A+ P PP TP P P P LQ P
Sbjct: 322 NAATPLPATLP-------PSPPLATPLPLAPPSPSAPPSLQTLP 358
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 107 bits (267), Expect = 2e-22
Identities = 356/1416 (25%), Positives = 449/1416 (31%), Gaps = 237/1416 (16%)
Query: 31 SQPPLEDNTP-----ATRTTKGAREAGGQAQAMELPEA----QPRQARDG-ELKPPSLRG 80
+QPP+ + P A T G ++ G + ++ E P+ A E P
Sbjct: 167 AQPPVLGHGPRFISIAGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDN 226
Query: 81 QAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENP 140
AP++T +G P+TP R + R GR ++ I +S P ++ EN
Sbjct: 227 LAPAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPP---DSAENQ 283
Query: 141 QLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQE---PPSSFTSTNYT 197
+ +P+ +TP AP P P + G + E P S T T
Sbjct: 284 --TSTDIPKTETP------APNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELG-T 334
Query: 198 SPSATPRPPAPGPPQSRG--------TSPLQPGSYPEYQASGADSWPPAAENSFPGANFG 249
+ R G + G S Q +P GA P E G F
Sbjct: 335 LETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEK---GQQFE 391
Query: 250 VPPAEP----------EPIPKGSRPGGSPRGVSFQFPFPALHGASTKP-----FPADVAG 294
PP P P P G P G + P + G P P AG
Sbjct: 392 GPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAG 451
Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVG-TGPAYP--LPTQPAPSPLPCYQGQPG-----GLN 346
+F P+ F Q Q + + GP P L +P P LP + G G G
Sbjct: 452 GSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQ 511
Query: 347 RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILP-ERPPSAQDGLGSTRGPPSSLPQRH 405
L G PG RP +D + LP + P G G P QR
Sbjct: 512 GPRGLQGPHGPPGRVGKMGRPGADG-----ARGLPGDTGPKGDRGFDGLPGLPGEKGQRG 566
Query: 406 FPGQAYRASGVDTSPGPP--DTELAAPGPP----PARLP---QLWDPTAAPYPT-PPG-- 453
G PGPP D E A GPP A P L P +P PT PG
Sbjct: 567 DFGHV-------GQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVT 619
Query: 454 ---GPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVL--PTARPSPHGMEMLSRLPFPA 508
G A ++ G+P P + S LP PQ L P G + LP
Sbjct: 620 GIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSD 679
Query: 509 G--------GPEWQGGSQGALGTAGKT--PGPREKLPAVRSSQGGSPALFTYNGMTDPGA 558
G GP + G+QG G+AG PGPR V+ + G+ L G
Sbjct: 680 GPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR----GVKGT-SGNRGLQGEKGEKGEDG 734
Query: 559 QPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPL--------PSPATNTAGSTCSSLSP 610
P F G + G P P PR G E P P + +
Sbjct: 735 FPGFKGDVGLK-GDQGKPGAPGPR--GEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791
Query: 611 MSSSPANPSSEES-QLPGPLGPSAFFHPPTHPQETGSPFPSPE--PPHSLPTHYQPEPAK 667
+ P P + S PGPLGP +TG P E PP S QP A
Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGP---IGEKGKSGKTGQPGLEGERGPPGSRGERGQP-GAT 847
Query: 668 AFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQ 726
P P +G +GA P E G GLQG P P P P H
Sbjct: 848 GQPGPKGDVGQDGA---------PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGR---- 894
Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGH---QRSPGPPGLPSPPAAPRVP 783
R G+L + K G GPPG P PP +P
Sbjct: 895 -----PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLP 949
Query: 784 ADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP-FPLPASDLDMEDDAKLDS 842
GL G GK+ P P P P P ++ D
Sbjct: 950 -----GLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTG---LKGDKGPPG 1001
Query: 843 LITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPL- 901
+ + E P E P GP G + G T + P PL
Sbjct: 1002 PVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLG 1061
Query: 902 -----PAATPDPQTPRPGDRGCPAR-------------GRPKTRSLGLAPTEADAPSQGR 943
AA P + GD G P G+P R G A + G
Sbjct: 1062 PLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIR--GPAGHPGPPGADGA 1119
Query: 944 QQRRGKQLKLFRKDLDSG-----GAAEGSGSGGGGRASGLRPRRND--GLGERPPPRPRR 996
Q RRG LF + D G G G G G + D +G P PR
Sbjct: 1120 QGRRGPP-GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRG 1178
Query: 997 PRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQ 1056
P Q P + ++ P +P P R DP A G I
Sbjct: 1179 P--QGP-TGSEGTPGLPGGVGQPGAVGEKGER--GDAGDPGPPGAPG----------IPG 1223
Query: 1057 QKNRLREYDFASESEEDEQPPPRG-PGFRGRRGR-GEKRKEVELTQGPREDEPQKPRKAA 1114
K + E + S P +G PG G +G G +L GP D +
Sbjct: 1224 PKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDL--GPPGDPGVSGIDGS 1281
Query: 1115 RQEAGGDGAPANPEEPGGS-RPGPGRSPQARGPS-------RSLETGAAAREG------- 1159
E G G P PG S PG P RGPS R E GA G
Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341
Query: 1160 -GPKCADRP--SVAPKDPLQVPTNT-ETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215
GP A P V P+ +P E P P P D+ E
Sbjct: 1342 TGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGE 1401
Query: 1216 -------ALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTP 1268
L PP AGE G GL + PP + D G P P GSL + P P
Sbjct: 1402 KGHIGLIGLIGPPGE-AGEKG-DQGLPGVQGPPGPKGDPGPPGPIGSLGHPGP------P 1453
Query: 1269 GVGSLLGGPGGTQAPVSHNSKDP--PARQPGEFLAP 1302
GV LG G +P S + PA PG AP
Sbjct: 1454 GVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489
Score = 75.9 bits (185), Expect = 8e-13
Identities = 226/908 (24%), Positives = 283/908 (31%), Gaps = 196/908 (21%)
Query: 2 PGER----PRGAPPPT-------MTGDLQPRQVASSPGHPSQPPLEDNTPATRT------ 44
PG R PRG+P PT + G + PG P P + N +
Sbjct: 598 PGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGL 657
Query: 45 --TKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQ-------APSSTPGKRGSPQT 95
T G + G LP + G P +G P PG RG T
Sbjct: 658 IGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGT 717
Query: 96 PPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTL-----DETPENPQLEAAQLPEV 150
R LQ G +G P + +G+ + KP ++ PE P+ +A Q E
Sbjct: 718 SGNRG-LQGEKGEKGE-DGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEE 775
Query: 151 DTPQGPGTGAPLR-PGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSATPRPPA- 207
P G L PGLP +P + +GF P S P
Sbjct: 776 GPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF-------PGPLGPIGEKGKSGKTGQPGL 828
Query: 208 ---PGPPQSRGT-----SPLQPGSYPEYQASGADSWPPAAENSFPGAN----FGVPPAEP 255
GPP SRG + QPG + GA P E PG F P P
Sbjct: 829 EGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIP--GEKGLPGLQGPPGFPGPKGPP 886
Query: 256 EPIPKGSRPG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313
K RPG G + FQ G + P PA V G PQG
Sbjct: 887 GHQGKDGRPGHPGQRGELGFQ-------GQTGPPGPAGVLG--------------PQGK- 924
Query: 314 PEEAVGTGPAYPLPTQPAPSPL--PCYQGQPGGLNRHSDLSGALSSPG--------AAHS 363
TG PL + P P P QG PG L G L PG
Sbjct: 925 ------TGEVGPLGERGPPGPPGPPGEQGLPG-LEGREGAKGELGPPGPLGKEGPAGLRG 977
Query: 364 APRPFSDSLHKSLTKILPERPPSAQDGLGST---RGPPSSLPQRHFPGQAYRASGVDTSP 420
P P T + ++ P G + RGP PGQ SG +
Sbjct: 978 FPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQ----SGSEGPV 1033
Query: 421 GPPDT-----ELAAPGPP-----PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPS- 469
GP E PGP P L L P AA GP G P
Sbjct: 1034 GPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAA-------GPSGEEGDKGDVGAPGH 1086
Query: 470 PGQRLCLPQSAPLPWPQVL-PTARPSPHGMEMLSRLPFPAG--GPEWQGGSQGALGTAGK 526
G + + P P + P P P G + P G G + G +G +G G
Sbjct: 1087 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGP 1146
Query: 527 T--------PGPREKLPAVRS-SQGGSPALFTYNGMTDPGAQP-LFFGVAQPQV------ 570
PG + ++ V S G+P G T P L GV QP
Sbjct: 1147 PGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGE 1206
Query: 571 -------SPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623
P G P +P P+ +S PS A G P A S +
Sbjct: 1207 RGDAGDPGPPGAPGIPGPKGDIGEKGDSG-PSGAAGPPGKK----GPPGEDGAKGSVGPT 1261
Query: 624 QLPGPLGP------SAFFHPPTH---PQETGSPFP--------SPEPPHSL-PTHYQ--- 662
LPG LGP S P P + G P P +P PP P+ +
Sbjct: 1262 GLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGRE 1321
Query: 663 ----PEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPE--------VGRGGLQGFP-RAP 709
+ AK P P G G P GPE VG GL G P +
Sbjct: 1322 GREGEKGAKGEPGPDGPPGRTGPMGA--RGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMG 1379
Query: 710 PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG 769
PP P L D T + ++ + L + G + G Q PG
Sbjct: 1380 PPGPLGPSGLPGLKGD------TGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPG 1433
Query: 770 PPGLPSPP 777
P G P PP
Sbjct: 1434 PKGDPGPP 1441
Score = 58.2 bits (139), Expect = 2e-07
Identities = 241/1074 (22%), Positives = 329/1074 (30%), Gaps = 210/1074 (19%)
Query: 466 GQPS---PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--GSQGA 520
G+P+ GQ+ P AP P V P+ P P G P PAG P G G +G
Sbjct: 379 GEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGP 438
Query: 521 LGTAGKTP----GPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTP 576
GT P G K P V Q + A+ ++ G +P P G P
Sbjct: 439 PGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRP--GPVGLP 496
Query: 577 SLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFH 636
P + G +E P + M A+ + GP G F
Sbjct: 497 G--HPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDG 554
Query: 637 PPTHPQETGSP-----FPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691
P P E G P PP P P P G G L P
Sbjct: 555 LPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGP----PGPTGQAGEPGPRGLLGPRGSP 610
Query: 692 HEGPEVGRGGLQGFPRA-----PPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAF 746
G G+ G P A PP P
Sbjct: 611 GPTGRPGVTGIDGAPGAKGNVGPPGEP--------------------------------- 637
Query: 747 LAHRQFCGLLLARAKDGHQRSPGP------PGLPSPPAAPRVPA-DAHAGLLSHAKTFLL 799
G + G Q PGP PG PP P +P G L H
Sbjct: 638 -------GPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGP 690
Query: 800 AGDAQAEGKDDPLRTGFLPSLAATP-FPLPASDLDMEDDAKLDSLITEALNGMEYQSDNP 858
G+ A+G P A P +P P + L + G + + P
Sbjct: 691 TGEKGAQGP---------PGSAGPPGYPGPRGVKGTSGNRGL-----QGEKGEKGEDGFP 736
Query: 859 EIDSSFIDVFADE-EPS--GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGD 915
+ + D+ +P GPRG K +AG E P +A + PG
Sbjct: 737 GFKGD-VGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPG---SAGEKGKLGVPGL 792
Query: 916 RGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRA 975
G P R PK S+G +G+ + G+
Sbjct: 793 PGYPGRPGPKG-SIGFPGPLGPIGEKGKSGKTGQP------------------------- 826
Query: 976 SGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPR----VPRAAALPEETRSSRRRRLP 1031
GL GER PP R R Q PG+ P P+ A +P E + P
Sbjct: 827 -GLE-------GERGPPGSRGERGQ-PGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP 877
Query: 1032 PRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGR-G 1090
P+ G G+ + E F ++ PP G G +G+ G
Sbjct: 878 GFPGPKGPPGHQGKDGRP------GHPGQRGELGFQGQTG-----PPGPAGVLGPQGKTG 926
Query: 1091 EKRKEVELTQGPR-----EDEPQKPRKAARQEAGGDGAPANP---EEPGGSR--PGPGRS 1140
E E +GP E P R+ A G+ P P E P G R PGP
Sbjct: 927 EVGPLGE--RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGG 984
Query: 1141 PQARGPSRSL----ETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQE 1196
P GP+ G G P +R + P + +P + + P+
Sbjct: 985 PGDPGPTGLKGDKGPPGPVGANGSP--GERGPLGPAGGIGLPGQSGSEGPVGPA------ 1036
Query: 1197 AKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSL 1256
K+ E P T + + P G +G PG P + D G P GS
Sbjct: 1037 GKKGSRGERGPPGPTG-KDGIPGP----LGPLGP-PGAAGPSGEEGDKGDVGAPGHKGSK 1090
Query: 1257 ANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPA--RQPGE-----FLAPVANPSST 1309
+ G PG+ G PG A + + PP Q G+ F+ + P
Sbjct: 1091 GDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQ 1150
Query: 1310 ACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQ-PYSSPHSELFLGPKDLAGCFLE 1368
P P ++ G + P G P +GPQ P S + G G E
Sbjct: 1151 GLPGPPGEKGEVGDVG------SMGPHGAP-GPRGPQGPTGSEGTPGLPGGVGQPGAVGE 1203
Query: 1369 ELHPKPSARDAPPASSSCLCQDGE--DAGSLEPQLPRSPPGTAETEPGRAASPPTLESSS 1426
+ + PP + G+ + G P PPG + PG + ++ +
Sbjct: 1204 KGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPG-KKGPPGEDGAKGSVGPTG 1262
Query: 1427 LFPDL--------------PVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPS 1466
L DL P ++ DP G SG P A PP K PS
Sbjct: 1263 LPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA-PGPPGKRGPS 1315
Score = 55.1 bits (131), Expect = 1e-06
Identities = 94/359 (26%), Positives = 128/359 (35%), Gaps = 41/359 (11%)
Query: 3543 LDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA-EGKRAPLVFSGKRRAPGA 3601
L G RP + S G PGPL P+G + G GQ EG+R P G+R PGA
Sbjct: 792 LPGYPGRPGPKGSIGFPGPLG----PIGEK-GKSGKTGQPGLEGERGPPGSRGERGQPGA 846
Query: 3602 RGRCAP--DHFQEDHL-LQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAA 3658
G+ P D Q+ + EK + GP G G P +
Sbjct: 847 TGQPGPKGDVGQDGAPGIPGEKGLPGLQ-----GPPG--FPGPKGPPGHQGKDGRPGHPG 899
Query: 3659 STPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGG 3718
+ P G L P +G + P + PGP PG +
Sbjct: 900 QRGELGFQGQTGPPGPAGVLGP----QGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955
Query: 3719 GSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREA-GEQGPHGSL 3777
G A G+L P+ P P+ P GP G++GP G +
Sbjct: 956 G-----AKGELGPPGPLGKEGPAGLRGFPGPKGGPG-------DPGPTGLKGDKGPPGPV 1003
Query: 3778 G----PKEKGESSTKRKKGQVPGPARSES-VGSFGRAPSAPDK-PPRTPRKQATPSRVLP 3831
G P E+G G +PG + SE VG G+ S ++ PP K P + P
Sbjct: 1004 GANGSPGERGPLGPAGGIG-LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGP 1062
Query: 3832 TKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAE 3890
P P + + PGH K G A P G+P +R P GA+ A+
Sbjct: 1063 LGP-PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQ 1120
Score = 54.7 bits (130), Expect = 2e-06
Identities = 133/534 (24%), Positives = 178/534 (33%), Gaps = 74/534 (13%)
Query: 3413 LRGGRQPFAFRGVR-RPGA---PGQKARALEGTLPSKRRRVAMPG-----SAPGP----- 3458
L G R P RG R +PGA PG K + P +PG PGP
Sbjct: 828 LEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPG 887
Query: 3459 --GED----RPPPRGSSPILSEGSLPALLHLCS------EVAPSTTKGWPETLERPVDPV 3506
G+D P RG + P + EV P +G P P +
Sbjct: 888 HQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG 947
Query: 3507 THPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQA 3566
+ G E P P PA L G G + G PGP+
Sbjct: 948 LPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANG 1007
Query: 3567 LP--LGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSS 3624
P G P G G P+ +GK+ + G RG P +D + +
Sbjct: 1008 SPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTG--KDGIPGPLGPLGP 1065
Query: 3625 SHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSK-ALKFPV-HPRKAVGSLA--- 3679
G G KG P G + S D+ A P + ++ P HP A
Sbjct: 1066 PGAAGPSGEEGD--KGDVGAP-GHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGR 1122
Query: 3680 ---PGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATT 3736
PG + ++G++ P P QG P PG K G G + A
Sbjct: 1123 RGPPGLFGQKGDDGVRGFVGVIGP-PGLQGLPGP-PGEKGEVGDV-----GSMGPHGAPG 1175
Query: 3737 PAKPSFPSRSPAPERLPARAQAKSCT--KGPR-EAGEQGPHGSLG---PK----EKGESS 3786
P P P+ S LP KG R +AG+ GP G+ G PK EKG+S
Sbjct: 1176 PRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG 1235
Query: 3787 TKRKKGQVPG----PARSESVGSFGRAPSAPDKPPR----------TPRKQATPSRVLPT 3832
G PG P + GS G D P +P ++ P V
Sbjct: 1236 PSGAAGP-PGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGP 1294
Query: 3833 KPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGA 3886
P P + +P P ++ GH R+ R G+ +G P P T GA
Sbjct: 1295 GP-PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGA 1347
Score = 52.0 bits (123), Expect = 1e-05
Identities = 125/475 (26%), Positives = 159/475 (33%), Gaps = 87/475 (18%)
Query: 3428 PGAPGQKAR-ALEGTLPSKRRRVAMPGSAPG-------PGED--RPPPRGSSPILSEG-- 3475
PG PG K EG P R + P PG PG D R P + P G
Sbjct: 496 PGHPGLKGEEGAEG--PQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFD 553
Query: 3476 SLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNH-----QECPPPSLSPF 3530
LP L +G + +P P RG E P + P L P
Sbjct: 554 GLPGL------PGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPR 607
Query: 3531 PAALADGR-GDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAEGKRA 3588
+ GR G +DGA N PG PGP QQ LP P G G G++
Sbjct: 608 GSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIG--TPGEKG 665
Query: 3589 PLVFSGKRRAPGARGRCA-PDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAG 3647
P G PG+ G P H + S+ GPRG KG++ G
Sbjct: 666 PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGV--KGTSGN-RG 722
Query: 3648 CQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGS 3707
Q ++ P G++ + G KP PGP +
Sbjct: 723 LQGEKGEKGEDGFPG----------------FKGDVGLKGDQG-KPGA----PGPRGE-D 760
Query: 3708 GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL--------PARAQAK 3759
G P + G + P + P P +P R P P+ P + K
Sbjct: 761 GPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGR-PGPKGSIGFPGPLGPIGEKGK 819
Query: 3760 SCTKG-PREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPR 3818
S G P GE+GP GS +GE GQ PGP VG G AP P +
Sbjct: 820 SGKTGQPGLEGERGPPGS-----RGERGQPGATGQ-PGP--KGDVGQDG-APGIPGE--- 867
Query: 3819 TPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRK-AEPGHTQRKDRLGKAFPQGRP 3872
+ LP P P+ PP Q K PGH ++ LG G P
Sbjct: 868 ---------KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPP 913
Score = 51.6 bits (122), Expect = 2e-05
Identities = 281/1166 (24%), Positives = 358/1166 (30%), Gaps = 216/1166 (18%)
Query: 1633 PASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDV 1692
P SF A + Q L P P G PV G GL EG P
Sbjct: 458 PVSFQQAQAQAV-LQQTQLSMKGPPGPVGLTGRPGPVGLPG--HPGLKGEEGAEGPQGPR 514
Query: 1693 CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCE--QRGGFLP 1750
L P PG G + + D P + D L LP E QRG F
Sbjct: 515 GLQGPHGPPGR---VGKMGRPGADGARGLPGDT-GPKGDRGFDGLPGLPGEKGQRGDF-- 568
Query: 1751 EPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGR 1810
H G P P +G PP P G + +G R
Sbjct: 569 -------GHVGQPGPPGEDGE----------RGAEGPP----GPTGQAGEPGPRGLLGPR 607
Query: 1811 AGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPAL 1870
G PT GRPG G + AP GA P G P P H S+ L
Sbjct: 608 --GSPGPT-GRPGVTGIDGAP-GAKGNVGPPGE-------PGPPGQQGNHGSQ-----GL 651
Query: 1871 SPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGS 1930
P + PG GI GL P + P + G EG T E G + G
Sbjct: 652 PGPQGLIGTPGEKGPPGNPGIPGL----PGSDGP--LGHPGHEGPTGEKGAQGPPGSAGP 705
Query: 1931 PGGVQVTTLPAVAGHQLGLEAD-------------GHWGLLGQAEKTQGQGTANQLQPEN 1977
PG + +G++ GL+ + G GL G K G + PE
Sbjct: 706 PGYPGPRGVKGTSGNR-GLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764
Query: 1978 GVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRES 2037
P G A P +A G L G + P P P E
Sbjct: 765 ---PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKG----SIGFPGPLGPIGEK 817
Query: 2038 LALALTAAHSRSGSEGRTPERAS--SPGLNKPLLATGDSPAPSVGDLAAC-APSPTSAAH 2094
T G G R PG ATG P P GD+ AP
Sbjct: 818 GKSGKTGQPGLEGERGPPGSRGERGQPG------ATGQ-PGPK-GDVGQDGAPGIPGEKG 869
Query: 2095 MPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRD---------PPGPQQLLACSPAWA 2145
+P GP P P G G+ P P R PPGP +L
Sbjct: 870 LPGLQGPPGFPGPKGPPGHQ--GKDGR-PGHPGQRGELGFQGQTGPPGPAGVLG------ 920
Query: 2146 PLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSV 2205
P + V + G P P + +E G L G PL P +
Sbjct: 921 PQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGEL--GPPGPLGKEG---PAGL 975
Query: 2206 SAVTCTHSGDTPKDSTLRIPEDSRKEKLWESP-GRATSPPLAGAVSPSVAVRATGLSST- 2263
G P D P + +K P G SP G + P+ + G S +
Sbjct: 976 RGFPGPKGG--PGDPG---PTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSE 1030
Query: 2264 ----PTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPS-------NTARLGH 2311
P G + G RG PGP + G P P P + PS + GH
Sbjct: 1031 GPVGPAGKKGSRGERGPPGPTGKD-GIPGPLGPLGPP---GAAGPSGEEGDKGDVGAPGH 1086
Query: 2312 R--EGQAVTAVPTEPPTLQG-AGPDSPACLEGEMGTSSKEPEDPGT-PETGRSGATKMPR 2367
+ +G A P P ++G AG P +G G PG + G G
Sbjct: 1087 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP----PGLFGQKGDDGVRGFVG 1142
Query: 2368 VTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKP 2427
V P GL D S P H + PQG P G + G +
Sbjct: 1143 VIGPPGLQGLPGPPGEKGEVGDVGSMGP--HGAPGPRGPQG-PTGSEGTPGLPGGVGQPG 1199
Query: 2428 ASTENGQWKGQAPHGPVTCEVCAA-------SFRSGP-GLSRHKARKHRP-HPGAPAEPS 2478
A E G+ GP SGP G + +K P GA
Sbjct: 1200 AVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVG 1259
Query: 2479 PAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPG 2538
P LP PP VSG + +GDP V P P S E APG
Sbjct: 1260 PTGLPGD---------LGPPGDPG--VSGIDGSPGEKGDPGDVGGPGPPGASGEP-GAPG 1307
Query: 2539 SPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRR-EPTVDSPS 2597
P + P+ H E REG + + EP D P
Sbjct: 1308 PPGKR-----GPSGH-----------------------MGREGREGEKGAKGEPGPDGP- 1338
Query: 2598 HSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEG-- 2655
G++ + R+ E + + V G P PS ++G
Sbjct: 1339 --PGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDT 1396
Query: 2656 GPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDR--MLCPGRMDGAALG 2713
GP+ + + +GP E + DQ G G Q PPG + PG + +LG
Sbjct: 1397 GPKGEKGHIGLIGLIGP-PGEAGEKGDQ-----GLPGVQGPPGPKGDPGPPGPI--GSLG 1448
Query: 2714 EQ-------PTGQKGA-SARGFWGPR 2731
P GQKG+ + G GPR
Sbjct: 1449 HPGPPGVAGPLGQKGSKGSPGSMGPR 1474
Score = 40.8 bits (94), Expect = 0.027
Identities = 106/459 (23%), Positives = 143/459 (31%), Gaps = 72/459 (15%)
Query: 1683 EGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPC 1742
+GD+ PP + P+ PGP G+ + P Q+ +D +R
Sbjct: 1093 KGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP----------PGLFGQKGDDGVRGFV- 1141
Query: 1743 EQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHA 1802
G + PG +G P P + GD + + P GA
Sbjct: 1142 ----GVIGPPGL-----QGLPGPPG----------EKGEVGD----VGSMGPHGAPGPRG 1178
Query: 1803 AQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPS 1862
QG + L G+PG G E G + P G P ++ PS
Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVG-EKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPS 1237
Query: 1863 RRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPP-RVNPSGLEGGTVEGGK 1921
+ P P PG AK G GL P PP SG++G E G
Sbjct: 1238 GAAGPPGKKGP------PGEDGAKGSVGPTGL----PGDLGPPGDPGVSGIDGSPGEKGD 1287
Query: 1922 VACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSP 1981
G PG P G + GH G G+ + +G P P
Sbjct: 1288 PGDVGGPGPPGASGEPGAPGPPGKR---GPSGHMGREGREGEKGAKGEPGPDGPPGRTGP 1344
Query: 1982 -GGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSP-----PSPNR 2035
G V + GP LL G+ M P+ P P
Sbjct: 1345 MGARGPPGRVGPEGLRGIPGPVGEPGLL----GAPGQMGPPGPLGPSGLPGLKGDTGPKG 1400
Query: 2036 ESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD-SPAPSVGDLAACAPSPTSAAH 2094
E + L G G ++ PG+ P GD P +G L P P A
Sbjct: 1401 EKGHIGLIGLIGPPGEAGEKGDQ-GLPGVQGPPGPKGDPGPPGPIGSLG--HPGPPGVA- 1456
Query: 2095 MPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133
GPL ++ SP + G G PA P PPG
Sbjct: 1457 -----GPLGQKGSKGSPG-SMGPRGDTGPAGPP--GPPG 1487
Score = 40.0 bits (92), Expect = 0.046
Identities = 35/118 (29%), Positives = 41/118 (34%), Gaps = 13/118 (11%)
Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPG-----DPWGQEGEAKKDSPGE 3241
P G GS L + +P +G+R G PG P G GE P
Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSG 1238
Query: 3242 RAKPRARSTPSNPDGAATPDSASATAL-ADAGSPGPPRT-----TPSPSPDPWAGGEP 3293
A P + P DGA S T L D G PG P +P DP G P
Sbjct: 1239 AAGPPGKKGPPGEDGA--KGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGP 1294
Score = 39.3 bits (90), Expect = 0.078
Identities = 137/542 (25%), Positives = 175/542 (32%), Gaps = 134/542 (24%)
Query: 3452 PGSAPGPGE--------DRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWP--ETLER 3501
PG GPG+ D+ PP P+ + GS + P+ G P E
Sbjct: 979 PGPKGGPGDPGPTGLKGDKGPP---GPVGANGSPGER----GPLGPAGGIGLPGQSGSEG 1031
Query: 3502 PVDPV----THPIRGCELPSNHQECPPP--SLSPFPAALADGR-GDCALDGALERPENEA 3554
PV P + RG P+ P P L P AA G GD GA ++
Sbjct: 1032 PVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKG 1091
Query: 3555 SPGSPGPLLQQAL--PLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCA---PDH 3609
G GP Q + P G P PGA G A+G+R P G++ G RG P
Sbjct: 1092 DKGDAGPPGQPGIRGPAGHPGP-PGADG--AQGRRGPPGLFGQKGDDGVRGFVGVIGPPG 1148
Query: 3610 FQEDHLLQKEK----EVSSSHMVSEGGPRG----TFHKGSATKPAGC-------QSSSKD 3654
Q EK +V S GPRG T +G+ P G + +
Sbjct: 1149 LQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERG 1208
Query: 3655 RSAASTPSKALKFPVHPRKAVGSLA----------PGELARGTENGMKPAT-PKAKPG-- 3701
+ P A P P+ +G PG+ E+G K + P PG
Sbjct: 1209 DAGDPGPPGAPGIP-GPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDL 1267
Query: 3702 --PSSQG----SGSPRPGTKTG--GGSQPQPASGQLQSETATTPAKPSFPSR-------- 3745
P G GSP G GG P ASG+ P P P +
Sbjct: 1268 GPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE--------PGAPGPPGKRGPSGHMG 1319
Query: 3746 ------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQ 3793
P P+ P R P G +G G GP GE GQ
Sbjct: 1320 REGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGP--VGEPGLLGAPGQ 1377
Query: 3794 V--PGPARSES-------------------VGSFGRAPSAPDKPPR-TPRKQATPS-RVL 3830
+ PGP +G G A +K + P Q P +
Sbjct: 1378 MGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGD 1437
Query: 3831 PTKPKP-NSQNKPRPP----PSEQR--KAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAV 3883
P P P S P PP P Q+ K PG + G A P G PP +
Sbjct: 1438 PGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPG-----PPGAPAEL 1492
Query: 3884 HG 3885
HG
Sbjct: 1493 HG 1494
Score = 33.5 bits (75), Expect = 4.3
Identities = 64/280 (22%), Positives = 85/280 (30%), Gaps = 33/280 (11%)
Query: 3635 GTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPA 3694
G KG+ +PA + + P P+ VG P G P
Sbjct: 371 GAGEKGAKGEPAVIEKGQQFEGPPGAPG--------PQGVVGPSGPPG-PPGFPGDPGPP 421
Query: 3695 TPKAKPG-PSSQGSGSPRPGTK-------TGGGSQPQPASGQLQSETATTPAKPSFPSRS 3746
P PG P G P PGT GG + P S Q A
Sbjct: 422 GPAGLPGIPGIDGIRGP-PGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGP 480
Query: 3747 PAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE-KGESSTKRKKGQVPGPARSESVGS 3805
P P L R P GE+G G GP+ +G + G++ P + G
Sbjct: 481 PGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGL 540
Query: 3806 FGRAPSAPDKP----PRTPRKQATPSRV----LPTKPKPNSQNKPRPPPSEQRKA-EPGH 3856
G D+ P P ++ P P + + PP +A EPG
Sbjct: 541 PGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGP 600
Query: 3857 TQRKDRLGKAFPQGRPLL-----RPPKRGTAVHGAEPAEP 3891
G P GRP + P +G EP P
Sbjct: 601 RGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPP 640
Score = 33.5 bits (75), Expect = 4.3
Identities = 54/185 (29%), Positives = 70/185 (37%), Gaps = 42/185 (22%)
Query: 2653 VEGGPEADGEQPPRLATLGPGVM--EGAAETDQEALCAGETGAQKPPGDRML--CPGRMD 2708
++G P A G P PG G+ G G + PPG+ + PG D
Sbjct: 621 IDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGS-D 679
Query: 2709 GAALG----EQPTGQKGASAR-------GFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757
G LG E PTG+KGA G+ GPR GV SG+ + +
Sbjct: 680 GP-LGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR-----GVKGTSGNRGLQGE-----KG 728
Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASGSS 2817
E+G E+ P GF D QG P P +G GPEGP A +
Sbjct: 729 EKG--EDGFP-----GFKGDVGLKGD-------QGKPGAPGPRGE-DGPEGPKGQAGQAG 773
Query: 2818 AKDPP 2822
+ PP
Sbjct: 774 EEGPP 778
Score = 32.3 bits (72), Expect = 9.5
Identities = 51/224 (22%), Positives = 71/224 (31%), Gaps = 41/224 (18%)
Query: 2276 PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSP 2335
P +G P P R +G G ++ + + + PP PDS
Sbjct: 229 PAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWT--SSPP------PDSA 280
Query: 2336 ACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSP 2395
E + T + E P T P V + GL T S D ++
Sbjct: 281 ---ENQTSTDIPKTETPAP----NLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELG 333
Query: 2396 QSHRNASHQTPQGDP--LGPQ----DLKQRS----------RGYKKKPASTENGQWKGQA 2439
A+ + +GD +GP + R+ +G K +PA E GQ
Sbjct: 334 TLETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGP 393
Query: 2440 PHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP 2483
P P V S GP PG P P PA LP
Sbjct: 394 PGAPGPQGVVGPSGPPGPP----------GFPGDPGPPGPAGLP 427
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 107 bits (266), Expect = 3e-22
Identities = 159/608 (26%), Positives = 213/608 (35%), Gaps = 80/608 (13%)
Query: 144 AAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATP 203
AA+ P + TP+ PG+ P P P A LG P + + +
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPA-----ALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
Query: 204 RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSR 263
P GP +S GTS P S P ASG P A+N+ PG P + P +R
Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPP--ASGRGERAPPAKNTSPG-----PVSSPGRASGTTR 125
Query: 264 PGG-SPRGVSFQFPFPALHGAST---KPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG 319
PG +G+ G +T K T+GP P A A G
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAG 184
Query: 320 TGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLS------GALSSPGAAHSAPRPFSDSLH 373
T P P P+ P P +G ++ S+ S A P A RP S SL
Sbjct: 185 TEVGLPRPA-PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 374 KSLTKIL-PERP-PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPG 431
S T + P R PSA+ G+ R P + QA R V PP + A
Sbjct: 244 SSATPLSSPARSGPSAR---GTPRAPAHPSQPKPKGLQALRPPQVT----PPRKDAA--- 293
Query: 432 PPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTA 491
P L +++P TP P AA +S P+ L P LP A
Sbjct: 294 ------PALGPLSSSPLATP--SPSAALQSQAPPTLPATPHSSSLTCQLATP----LPLA 341
Query: 492 RPSPHGMEMLSRLPFPAGGPEWQG----GSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547
PSP L LP P P Q GS T P P L + + +P
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP--PLSPLATPPPQAPPA 399
Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVG--------ASPSESPLPSPATN 599
+ P + P A P +SP TPS P + + P P+ +P +
Sbjct: 400 LALPPLQAPPSPP-----ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454
Query: 600 TAGSTCS-SLSPMSSSPANPSSEESQLPG------PLGPSAFFHPPTHPQETGSPFPSPE 652
A S S +P S +P + ++ Q+P P+ PSA P P P +
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514
Query: 653 PPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPF------PHEGPEVGRGGLQGFP 706
PP P P +A P P + F P P + P V L P
Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574
Query: 707 RAPPPYPT 714
+PP PT
Sbjct: 575 PSPPASPT 582
Score = 102 bits (253), Expect = 1e-20
Identities = 198/777 (25%), Positives = 256/777 (32%), Gaps = 170/777 (21%)
Query: 10 PPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAME---------L 60
P G L PR PG P PP TPA GA A G+ E +
Sbjct: 17 PAARAPGLLTPRP----PGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 61 PEAQPRQA--RDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQ 118
PE+ PR R + + P+S G+R P P+ +P R +G P
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 119 RYILGIASSRT--KPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176
+ L I++ T + E P+ L A + P PGT +P R A
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSRA----AGT 185
Query: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236
E+G R +PSA PRPP GP +S ++ + P
Sbjct: 186 EVGLPR--------------PAPSARPRPPTEGPRKSVSSASEHSTTEPS---------- 221
Query: 237 PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHA 296
PAA P A G+ + + P SP A G S + P A +
Sbjct: 222 PAARRR-PSAGGGLQRPASRSLSSSATPLSSP----------ARSGPSARGTPRAPAHPS 270
Query: 297 FTNGPLVFAFHQPQGAWPEEAVGTGPAY-PLPTQPAPSPLPCYQGQPGGLNRHSDLSGAL 355
+ A PQ P + PA PL + P +P P S AL
Sbjct: 271 QPKPKGLQALRPPQVTPPRK--DAAPALGPLSSSPLATPSP---------------SAAL 313
Query: 356 SSPGAAHSAPRPFSDSLHKSLTKILPERPPS--AQDGLGSTRGPPSSLPQRHFPGQAYRA 413
S P S SL L LP PPS A L + PP++ P QA +
Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS-----QATTS 368
Query: 414 SGVDTS-------PGPPDTELAAPGP--PPA-RLPQLWDPTAAPYPTPPGGPLAATRSMF 463
G T P PP + LA P P PPA LP L P + P +PP PLA
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP-ASPPLSPLATPSPQA 427
Query: 464 FNG----------QPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPF--PAGGP 511
N P P + P S P P V P+A P L+ P P P
Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPPSQAPPSLAAPPLQVPPSPP 486
Query: 512 EWQGGSQGALGTAGKTPGPREKLPAV-------RSSQGGSPALFT--YNGMTDPGA---- 558
S A TP P+ P + PAL T + P A
Sbjct: 487 ASPPMSPSA------TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540
Query: 559 QPLFFGVAQPQVSPHGTPSLPPPRVVGA----------------SPSESPLPSPATNTAG 602
Q F A +SP TP P V+ A +P P P P T+ +G
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600
Query: 603 STCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQE--------TGSPFPSPEPP 654
+ P S S L GP + P+E G SP P
Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660
Query: 655 HSL--------------PTHYQPEPAKAFPF-PADGLGAEGAFQCLEETPFPHEGPE 696
L P ++ P P+ PA G G+ + ET EGPE
Sbjct: 661 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET----EGPE 713
Score = 90.5 bits (223), Expect = 3e-17
Identities = 161/631 (25%), Positives = 210/631 (33%), Gaps = 141/631 (22%)
Query: 8 GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATR-TTKGAREAGGQAQAMELPEAQPR 66
G P P M + R + G P P P T K A + P A+ R
Sbjct: 170 GTPSPAMAR--RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Query: 67 QARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPS-----RLAGRAEGSPPQ--- 118
+ G L+ P+ R + S+TP + P R +AP+ + G PPQ
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 119 -----RYILGIAS--------------SRTKPTLDETPENPQLE---AAQLPEVDTPQGP 156
LG S S+ PTL TP + L A LP P P
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL--APPSP 345
Query: 157 GTGAPLR--PGLPRTEAQPAAEELG------FHRCFQEPP-SSFTSTNYTSPSATPRPPA 207
L+ P P T A LG H PP S + +P A PP
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405
Query: 208 PGPPQSRGTSPLQPGSYPEYQASGA---------DSWPPAAENSFPGANFGVPPAEPEPI 258
PP + PL P + P QA A S PP+ P + PPA P
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS----PPASPPVS 461
Query: 259 PKGSRPGGSPRGVS---FQFP--FPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313
P + P +P ++ Q P PA S P A PL A PQ
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA-- 519
Query: 314 PEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLH 373
A+ T P LP+ PA P GQ + S + S P + + P P + +
Sbjct: 520 -PPALATPPLQALPSPPASFP-----GQ-------APFSPSASLPMSPLATPPPQAPPVL 566
Query: 374 KSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP 433
+ +P PP A L + R PP+ P G + +PGPP PP
Sbjct: 567 AAPLLQVPPSPP-ASPTLQAPRRPPTPGPDTSVSGPRLTLA---LAPGPP--------PP 614
Query: 434 PARLPQ--LWDPTAAPYPT------------------------PPGGPLAATRSMFFNGQ 467
P+R P L P A + + PP LAA ++
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674
Query: 468 PSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKT 527
P+P APLPWP PA GP GS L T +T
Sbjct: 675 PAPPLAFRGAPGAPLPWP---------------------PATGP----GSADGLCTIYET 709
Query: 528 PGPREKLPAVRSSQGGSPALFTYNGMTDPGA 558
GP PA + G P+ T G GA
Sbjct: 710 EGPESATPAPGALDPG-PSPGTSGGKAAAGA 739
Score = 75.9 bits (185), Expect = 8e-13
Identities = 191/779 (24%), Positives = 256/779 (32%), Gaps = 214/779 (27%)
Query: 1830 APAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKD 1889
A AGA++ T L P P + P PP+ L G A
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGS-------------PRPPPPVTPAALRVLGAA---- 50
Query: 1890 GILGLQELTPAA---------QSPPRVNPSGLEGGTVEGGKVACGPAQG----------- 1929
G +G + L A +S PR P+ GT + PA G
Sbjct: 51 GAVGRKPLAERAGGIGGATIPESAPRAGPTR-SAGTSSRNPASRPPASGRGERAPPAKNT 109
Query: 1930 ------SPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPG- 1982
SPG TT P G + GL AE+T +G A + + +S G
Sbjct: 110 SPGPVSSPGRASGTTRPGPLGQK---------GLRISAEETVARGKATEAPKRSALSAGA 160
Query: 1983 ---------GTDNHASVN----ASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPT-P 2028
GT + A A + L P A +G R ++S E T P
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220
Query: 2029 SPPS------------PNRESLALALT--AAHSRSGSEGR-TPERASSPGLNKP------ 2067
SP + P SL+ + T ++ +RSG R TP + P KP
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
Query: 2068 ----LLATGDSPAPSVGDLAA---CAPSPTSA---------------AHMPCSLG-PLP- 2103
+ AP++G L++ PSP++A + + C L PLP
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
Query: 2104 --------------REDPLTSPSRAQGGLGGQL-----------PASPSCRDPPGPQQLL 2138
P T PS+A LG P SP PP L
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
Query: 2139 ACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPS 2198
A P AP SP P T SP P ALA LLQ SP P
Sbjct: 401 ALPPLQAP------------PSPPASPPLSPLATPSPQAP-NALAVHLLQAPFSPPPSPP 447
Query: 2199 SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVS------PS 2252
P S A TP + P L P SPP++ + + P
Sbjct: 448 VQAPFSPPASPPVSPSATPPS---QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
Query: 2253 VAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHR 2312
+A L+ P QA L P Q+ +PP + P G + +SPS + +
Sbjct: 505 LAAPPLQLAKPP----PQAPPALATPPLQALPSPPASFP-----GQAPFSPSASLPM--- 552
Query: 2313 EGQAVTAVPTEPPTLQG----AGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRV 2368
T P PP L P PA + + P PG P+T SG PR+
Sbjct: 553 -SPLATPPPQAPPVLAAPLLQVPPSPPA---SPTLQAPRRPPTPG-PDTSVSG----PRL 603
Query: 2369 TCPSTGLGLGRTTAPS-STASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKP 2427
T L G PS S +S H +++ TP + RGY
Sbjct: 604 T---LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP-----------EELRGY---- 645
Query: 2428 ASTENGQWKGQAPHGPVTCEVCA---ASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP 2483
++G G A P E+ A A++ GP R PGAP PA P
Sbjct: 646 ---DSGPEGGAAASPPPDAELAACHPAAWSRGPA----PPLAFRGAPGAPLPWPPATGP 697
Score = 75.5 bits (184), Expect = 1e-12
Identities = 192/818 (23%), Positives = 257/818 (31%), Gaps = 133/818 (16%)
Query: 1639 GHAALLPCAQED--LVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQ------ 1690
G AA P A+ L P SPR PV A G A G +
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPP----PPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 1691 DVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLP 1750
+PE + + GP AG+ ++ + + + + A ++ + P G
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG--TT 124
Query: 1751 EPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAP-PLDATWPFGASPSHAAQGHSAG 1809
PG Q A E AP + GA P SP+ A + +AG
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 1810 RAGGHLHPTAG---RPGFEGNEFAPAGAS--SLTAP----RGREAWLVPVPSPACVSNTH 1860
G P RP EG + + AS S T P R R + + PA S +
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920
+ PA S P + P S+ GLQ L P +PPR + +
Sbjct: 245 SATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP--------- 294
Query: 1921 KVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKT-----QGQGTANQLQP 1975
A GP SP T P+ A L QA T QL
Sbjct: 295 --ALGPLSSSP---LATPSPSAA-------------LQSQAPPTLPATPHSSSLTCQLAT 336
Query: 1976 ENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNR 2035
++P S+ P T P++ L + +LQ PSPP
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL-------GSPTLQATHSFLPSPPL--- 386
Query: 2036 ESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHM 2095
S TP + P L P L SP S PSP + +
Sbjct: 387 ---------------SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 431
Query: 2096 PCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQA 2155
L P P + P +A P SPS P LA P P +
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASP 489
Query: 2156 TTDTGAEDSPVAPPSLTTSPC-------DPKEALAGCLLQGEGSPLEDPSSWPPGSVSAV 2208
A P APP L P ALA LQ SP P+S+P
Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP---PASFP------- 539
Query: 2209 TCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP--SVAVRATGLSSTPTG 2266
G P + +P ++P +P L SP S ++A TP
Sbjct: 540 -----GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 594
Query: 2267 DEAQAGRGL-----PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARL-GHREGQAVTAV 2320
D + +G L PGP P +P T GHSS + S L G+ G A
Sbjct: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 654
Query: 2321 PTEPPTLQGA---------GPDSPACLEGEMGTSSKEP--EDPGTPE--------TGRSG 2361
+ PP + A GP P G G P PG+ + G
Sbjct: 655 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 714
Query: 2362 ATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHR 2399
AT P P G A + + S SP+ R
Sbjct: 715 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 752
Score = 70.1 bits (170), Expect = 4e-11
Identities = 192/802 (23%), Positives = 262/802 (32%), Gaps = 125/802 (15%)
Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR---GPSRSL-ETGAAAREGGPKCA 1164
K AAR A P PG RP P +P A G + ++ A R GG A
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 1165 DRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAAC 1224
P AP+ PT + + P+ P + E AP + + S P
Sbjct: 69 TIPESAPRAG---PTRSAGTSSRNPASRPPASGRG-----ERAPPAKNTSPGPVSSPGRA 120
Query: 1225 AGEMGASP----GLLIPEQPPPSRHD-TGTPKPSGSLANTAPHGSSPTPGVGS------- 1272
+G P GL I + +R T PK S A S PTPG S
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 1273 -LLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCD-PAG 1330
G G P PP P + ++ + S+T P P+ + G PA
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE-PSPAARRRPSAGGGLQRPAS 239
Query: 1331 FNRDPLGVPV---AKKGPQPYSSPHSELFLGPKDLAGCFLEELHPK---PSARDAPPASS 1384
+ P+ A+ GP +P + G L+ L P P +DA PA
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQALRPPQVTPPRKDAAPALG 297
Query: 1385 SCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSL 1444
S P SP +++ +PPTL ++ P SL
Sbjct: 298 PL---------SSSPLATPSPSAALQSQ-----APPTLPAT-------------PHSSSL 330
Query: 1445 SANRDSGLPFA----CADPPQKTVPSDPPYP--------SFLLLEEVSPMLPSHFPDLSG 1492
+ + LP A A P +T+PS P P L+ LPS P LS
Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS--PPLSP 388
Query: 1493 GKVLSKTCPPERTVVP-GAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSK 1551
PP + P A PS P +A S + + L + LQ
Sbjct: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH--------LLQAPF 440
Query: 1552 DTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREG 1611
+P A + PPSQ A P + S + S
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500
Query: 1612 AESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQK 1671
A +A +P P + P A LP APFSP A+ P+
Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATPPLQA--LPSPPASFPGQAPFSP-SASLPMSPLAT 557
Query: 1672 AGASKTGLCQA---EGDSRPPQDVCLPEPSKQPGPQLDAG------SLAKC--------- 1713
+ A + PP L P + P P D +LA
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617
Query: 1714 SPDQELSFPK-NKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPA 1772
SP LS P ++S+ + + LR GG P + PA + G
Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP-- 675
Query: 1773 VHLAPDLAFQGDGAPPLDATWPFGASPSHA--------AQG-HSAGRAGGHLH--PTAGR 1821
AP LAF+ GAP WP P A +G SA A G L P+ G
Sbjct: 676 ---APPLAFR--GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT 730
Query: 1822 PGFEGNEFAPAGASSLTAPRGR 1843
G + A AGASS + + R
Sbjct: 731 SGGKAAAGAGAGASSRSPKQAR 752
Score = 68.6 bits (166), Expect = 1e-10
Identities = 204/849 (24%), Positives = 255/849 (30%), Gaps = 184/849 (21%)
Query: 379 ILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLP 438
+L RPP GS R PP P A R G + G A G A +P
Sbjct: 24 LLTPRPP------GSPRPPPPVTPA------ALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP-----TARP 493
+ +AP P ++R+ S P P P P T RP
Sbjct: 72 E-----SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 494 SPHGMEML--SRLPFPAGGPEWQGGSQGALG------TAGKTPGPREKLPAVRSSQGGSP 545
P G + L S A G + + AL T+G TPG A RS G+
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 546 ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPR--VVGASPSESPLPSPATNTAGS 603
G+ +P S P PR V AS + PSPA S
Sbjct: 187 V-----------------GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229
Query: 604 TCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHP--PTHPQETGSPFPSPEPPHSLPTHY 661
L +S + S+ P GPSA P P HP + P P+ +L
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-----PKPKGLQAL---- 280
Query: 662 QPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSS 721
P + P D A G L +P P LQ +APP P S S
Sbjct: 281 --RPPQVTPPRKDAAPALGP---LSSSPLATPSPSAA---LQS--QAPPTLPATPHSSS- 329
Query: 722 ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPR 781
LTC+ L A P LPSPPA P
Sbjct: 330 ---------LTCQLATP------------------LPLAPPSPSAPPSLQTLPSPPATPP 362
Query: 782 VPADAHAG--LLSHAKTFLLAGDAQAEGKDDPLRTGFL--PSLAATPFPL---PASDLDM 834
A G L +FL + P L P L A P P P S L
Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 422
Query: 835 EDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAG---- 890
++L L +P + + F S P PS+ P ++
Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAAP 477
Query: 891 ---VTPESKAPPPL-PAATPDPQTP-----------RPGDRGCPARGRPKTRSLGLAPTE 935
V P A PP+ P+ATP PQ P +P + PA P ++L P
Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP-- 535
Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPR 995
A P Q +A S P L + PP P
Sbjct: 536 ASFPGQA----------------PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579
Query: 996 RPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELI---L 1052
P QAP R P P + + P T + P P R G +L
Sbjct: 580 SPTLQAP--RRPPTPGPDTSVSGPRLTLA----LAPGPPPPPSRSPSSTLSGPDLAGHSS 633
Query: 1053 KIVQQKNRLREYDFASESEEDEQPPP-------------RGP----GFRGRRGRGEKRKE 1095
LR YD E PPP RGP FRG G
Sbjct: 634 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG------- 686
Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155
L P E +G + PG PGP SP G + GA
Sbjct: 687 APLPWPPATGPGSADGLCTIYET--EGPESATPAPGALDPGP--SPGTSGGKAAAGAGAG 742
Query: 1156 AREGGPKCA 1164
A PK A
Sbjct: 743 ASSRSPKQA 751
Score = 67.0 bits (162), Expect = 3e-10
Identities = 104/390 (26%), Positives = 130/390 (33%), Gaps = 69/390 (17%)
Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-NTPATRTTKGAREAGGQAQAMEL 60
P P PPP L + + P P+ PPL TP+ + A A+ L
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP--------NALAVHL 435
Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120
+A PPS QAP S P P +P P QAP LA PP
Sbjct: 436 LQAP-------FSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPP--- 483
Query: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF 180
P +P + + P P P PL+ P +A PA
Sbjct: 484 --------------SPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPL 528
Query: 181 HRCFQEPPSSFTSTNYTSPSAT------PRPPAPGPPQSRG---TSPLQPGSYPEYQASG 231
+ PP+SF SPSA+ PP PP P P + P QA
Sbjct: 529 -QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587
Query: 232 ADSWP-PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPA 290
P P S P + P P P P SP + P A H +S P
Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPPPP------PSRSPSS-TLSGPDLAGHSSSATSTPE 640
Query: 291 DVAGHAFTNGPLVFAFHQPQ-----GAWPEEAVGTGPAYPL-----PTQPAPSPLPCYQG 340
++ G + +GP A P A A GPA PL P P P P G
Sbjct: 641 ELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698
Query: 341 QPGGLNRHSDLSG---ALSSPGAAHSAPRP 367
GL + G A +PGA P P
Sbjct: 699 SADGLCTIYETEGPESATPAPGALDPGPSP 728
Score = 63.9 bits (154), Expect = 3e-09
Identities = 129/507 (25%), Positives = 168/507 (33%), Gaps = 57/507 (11%)
Query: 2109 TSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWA----PL-EEADGVQATTDTGAED 2163
T +RA G L + P SP P P L A A PL E A G+ T E
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP--ES 73
Query: 2164 SPVAPP--SLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDST 2221
+P A P S TS +P P ++ S P S + T
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 2222 LRIP--EDSRKEKLWESPGRA---------TSPPLAGAVSPSVAVRATGLSSTPTGDEAQ 2270
LRI E + K E+P R+ TS P G SP++A R S G E
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR-----SRAAGTEV- 187
Query: 2271 AGRGLPGPDPQSRGAPPHTNPDRMPRG---HSSYSPSNTARLGHREGQAVTAVPTEPPTL 2327
GLP P P +R PP P + HS+ PS AR G + + +
Sbjct: 188 ---GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 2328 QGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVT------CPSTGLGLGRTT 2381
SPA + + P P P+ A + P+VT P+ G
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 2382 APSSTASDFQSDSPQSHRNASHQTPQGDPLG-PQDLKQRSRGYKKKPASTENGQWKGQAP 2440
A S ++ QS +P + H + L P L S P S + P
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS---PSAPPSLQT------LP 355
Query: 2441 HGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRK 2500
P T A + P L + P A P P A PA L PL PP
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA-LALPPLQAPPSPPAS 414
Query: 2501 KSHRVSGKERPNHSRGDPSHVTQ----PPPAQGSKEVLRAPGSPH-SQQLHPPS---PTE 2552
P H+ Q PPP+ + P SP S PPS P+
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474
Query: 2553 HEVDVKTPASKPRPDQAREDELHPKQA 2579
++ P S P P QA
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQA 501
Score = 62.4 bits (150), Expect = 9e-09
Identities = 121/496 (24%), Positives = 162/496 (32%), Gaps = 57/496 (11%)
Query: 3416 GRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAP---GPGEDRPPPRGSSPIL 3472
GR+P A R GA ++ G S P S P G GE PP + +SP
Sbjct: 54 GRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP-- 111
Query: 3473 SEGSLPALLHLCSEVAPSTTKGWPETLERPV---DPVTHPIRGCELPSNHQECPPPSLSP 3529
S P + P KG + E V P R ++ P+
Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171
Query: 3530 FPAALADGRGDCALDGALERPENEASPGSP--GP--LLQQALPLGASLPRPGARGQDAEG 3585
A+A + L RP A P P GP + A + P P AR + + G
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 3586 KRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSS---SHMVSEGGPRGTFHKGSA 3642
G + P +R L +SS S + G PR H S
Sbjct: 232 --------GGLQRPASRS-----------LSSSATPLSSPARSGPSARGTPRAPAHP-SQ 271
Query: 3643 TKPAGCQS--------SSKDRSAASTP--SKALKFPVHPRKAVGSLAPGELARGTENG-- 3690
KP G Q+ KD + A P S L P P A+ S AP L +
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP-SPSAALQSQAPPTLPATPHSSSL 330
Query: 3691 ---MKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQ--LQSETATTPAKPSFPSR 3745
+ P A P PS+ S P SQ + G LQ+ + P+ P P
Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390
Query: 3746 SPAPERLPARA-QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVG 3804
+P P+ PA A P + P + P+ + + P
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 3805 SFGRAPSAPDKPPRTPRKQATPSRVLP---TKPKPNSQNKPRPPPSEQRKAEPGHTQRKD 3861
F S P P TP QA PS P P P + P + +A P
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510
Query: 3862 RLGKAFPQGRPLLRPP 3877
+L K PQ P L P
Sbjct: 511 QLAKPPPQAPPALATP 526
Score = 59.3 bits (142), Expect = 7e-08
Identities = 94/399 (23%), Positives = 140/399 (35%), Gaps = 58/399 (14%)
Query: 3523 PPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALP-------LGASLPR 3575
PPP ++P + G +P E + G G + ++ P G S
Sbjct: 35 PPPPVTPAALRVLGAAGAVG-----RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 3576 PGARGQ-DAEGKRAPLVFSGKRRAPG---ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEG 3631
P +R G+RAP K +PG + GR A + L QK +S+ V+
Sbjct: 90 PASRPPASGRGERAP---PAKNTSPGPVSSPGR-ASGTTRPGPLGQKGLRISAEETVA-- 143
Query: 3632 GPRGTFHKGSATK-PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENG 3690
+G AT+ P S+ R S P+ P R++ A GTE G
Sbjct: 144 -------RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS--------RAAGTEVG 188
Query: 3691 MKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA--TTPAKPSFPSRSPA 3748
+ P A+P P ++G ++P PA+ + S PA S S S
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL-SSSAT 247
Query: 3749 PERLPARA--QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVG-- 3804
P PAR+ A+ + P + P G + + ++ GP S +
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 3805 --SFGRAPSAPDKPPRTPRKQ------ATPSRVLPTKPK--PNSQNKPRP---PPSEQRK 3851
S AP P TP ATP + P P P+ Q P P PPS+
Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
Query: 3852 AEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAE 3890
+ T + P PL PP + P +
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406
Score = 56.2 bits (134), Expect = 6e-07
Identities = 211/908 (23%), Positives = 270/908 (29%), Gaps = 179/908 (19%)
Query: 1172 KDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL----RSPPAACAGE 1227
+D + T P L P+ P P + A R P A AG
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 1228 MGASPGLLIPEQPP----------PSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGP 1277
+G G IPE P SR+ P SG AP + +PG S G
Sbjct: 65 IG---GATIPESAPRAGPTRSAGTSSRNPASRPPASGR-GERAPPAKNTSPGPVSSPGRA 120
Query: 1278 GGTQAPVSHNSKDPPARQPGEFLAP---VANPSSTACPKPSVLSSKISSFGCDPAGFNRD 1334
GT P P Q G ++ VA +T PK S LS AG RD
Sbjct: 121 SGTTRP-------GPLGQKGLRISAEETVARGKATEAPKRSALS----------AGARRD 163
Query: 1335 PLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDA 1394
G P P + S AG + P PSAR PP
Sbjct: 164 TSGPTPGT--PSPAMARRSRA-------AGTEVGLPRPAPSARPRPPTEG---------- 204
Query: 1395 GSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF 1454
PR +A SP S L P SLS++
Sbjct: 205 -------PRKSVSSASEHSTTEPSPAARRRPSAGGGL-----QRPASRSLSSSATPLSSP 252
Query: 1455 ACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAP-- 1512
A + P + P P +PS + + + P + PP + P P
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPP------------QVTPPRKDAAPALGPLS 300
Query: 1513 SLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELG 1572
S P S AL S + L + L QL P LA L
Sbjct: 301 SSPLATPSPSAALQSQ-APPTLPATPHSSSLTCQL-------ATPLPLAPPSPSAPPSLQ 352
Query: 1573 TGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPC 1632
T PP AT P + T S T + S +AT P P
Sbjct: 353 TLPSPP-------ATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT-------PPPQAPP 398
Query: 1633 PASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDV 1692
+ P A P A L A SP+ N A L QA PP
Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPN----------ALAVHLLQAPFS--PP--- 443
Query: 1693 CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEP 1752
P P + A SP P + A ++ SL P + +P
Sbjct: 444 --------PSPPVQAPFSPPASP------PVSPSATPPSQAPPSLAAPPLQ-----VPPS 484
Query: 1753 GTADQPHRGAPAPEAFGSPAVHLAP-DLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRA 1811
A P + P P + P LA APP AT P A PS A G+A
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS--FPGQA 542
Query: 1812 GGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALS 1871
P+A P +P AP A L+ VP S P L
Sbjct: 543 P--FSPSASLP------MSPLATPPPQAPPVLAAPLLQVPPSPPAS----------PTLQ 584
Query: 1872 PPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSP 1931
P R P PG S G L P PP +PS GP
Sbjct: 585 APRRP---PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS----------TLSGPDLAGH 631
Query: 1932 GGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVN 1991
+T + G+ G E G + G +P A
Sbjct: 632 SSSATSTPEELRGYDSGPEG----GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 687
Query: 1992 ASPKTALTGP--TEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRS 2049
P TGP +G + + +G +A +P PSP + ++ A A A SRS
Sbjct: 688 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 747
Query: 2050 GSEGRTPE 2057
+ R E
Sbjct: 748 PKQARLGE 755
Score = 56.2 bits (134), Expect = 6e-07
Identities = 128/549 (23%), Positives = 174/549 (31%), Gaps = 67/549 (12%)
Query: 876 PRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQT----PRPGDRGC---------PARG 922
PR P+ G P KS + + S P PAA P RP R PAR
Sbjct: 198 PRPPTEG-PRKSVSSASEHSTTEPS-PAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 923 RPKTRSLGLAPTEADAPS-QGRQQRRGKQLKLFRKDLDSG-GAAEGSGSGGGGRASGLRP 980
P R AP P +G Q R Q+ RKD G S ++ L+
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ- 314
Query: 981 RRNDGLGERPPPRPRRPRTQAPGSR-ADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKR 1039
+ PP P P + + + A P P P + + P ++ PP P +
Sbjct: 315 ------SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS---PPATPPSQA 365
Query: 1040 KARGGAWGKELI--------LKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGE 1091
G+ + L + A + PP P
Sbjct: 366 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 425
Query: 1092 KRKE---VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSR 1148
+ V L Q P P P +A + P + P P PS
Sbjct: 426 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485
Query: 1149 SLETGAAAREGGPKCADRPSVAP-----KDPLQVPTNTET---SEETRPSLDFPQEAKEP 1200
+ P A P AP K P Q P T P FP +A P
Sbjct: 486 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA--P 543
Query: 1201 ETAEESAPDSTEFTEALRSPPAACAGEMG------ASPGLLIPEQPPPSRHDTGTPKPSG 1254
+ S P S T ++PP A + ASP L P +PP DT P
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603
Query: 1255 SLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKP 1314
+LA P+ S L GP A S ++ P G P +++ P
Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 661
Query: 1315 SVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAG-CFLEELHPK 1373
+ + C PA ++R P P+A +G P GP G C + E
Sbjct: 662 ELAA-------CHPAAWSRGP-APPLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGP 712
Query: 1374 PSARDAPPA 1382
SA AP A
Sbjct: 713 ESATPAPGA 721
Score = 52.0 bits (123), Expect = 1e-05
Identities = 147/600 (24%), Positives = 180/600 (30%), Gaps = 96/600 (16%)
Query: 3193 SSAVAHLLNSITEPAPKHHRG-------KRSAGKAAGSPGDPWGQEGEAKKDSPGERAKP 3245
SSA H S TEP+P R +R A ++ S P + P R P
Sbjct: 210 SSASEH---STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA---RSGPSARGTP 263
Query: 3246 RARSTPSNPDG----AATPDSASATALADAGSPGP----PRTTPSPSPDPWAGGEPLLQA 3297
RA + PS P A P + A + GP P TPSPS + P L A
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323
Query: 3298 TPVHEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLG 3357
TP + C P P A S Q + P P L
Sbjct: 324 TPHSSSLT--------CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 375
Query: 3358 GAHGLLERPELQHT----PLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHL 3413
H L P L P L ++ A + Q + HL
Sbjct: 376 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 435
Query: 3414 RGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAP----GPGEDRPPPRGSS 3469
+ PF+ P +P +A P P AP P PP +S
Sbjct: 436 L--QAPFS-----PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488
Query: 3470 PILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSP 3529
P +S + P AP P L +P P P P PP S
Sbjct: 489 PPMSPSATPP------PQAPPPLAAPPLQLAKP--PPQAPPALATPPLQALPSPPAS--- 537
Query: 3530 FPAALADGRGDCALDGALERPENEASPGSPGPLLQ-----QALPLGASLPRPGARGQDAE 3584
FP L P +A P PLLQ A P + RP G D
Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597
Query: 3585 --GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSA 3642
G R L + P +R S S +S GP H SA
Sbjct: 598 VSGPRLTLALAPGPPPPPSR--------------------SPSSTLS--GPDLAGHSSSA 635
Query: 3643 TKPA----GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKA 3698
T G S + +AAS P A HP AP RG P P
Sbjct: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 695
Query: 3699 KPGPSSQG------SGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL 3752
PG S+ G + P T G P P+ G A A SRSP RL
Sbjct: 696 GPG-SADGLCTIYETEGPESATPAPGALDPGPSPG-TSGGKAAAGAGAGASSRSPKQARL 753
Score = 49.7 bits (117), Expect = 6e-05
Identities = 184/789 (23%), Positives = 251/789 (31%), Gaps = 138/789 (17%)
Query: 2014 SRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD 2073
+RA L +P PP P + L AA G+ GR P + G+ AT
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAA----GAVGRKPLAERAGGIGG---ATIP 71
Query: 2074 SPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133
AP G + S + A P + G R P + S G+ AS + R P
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR--ASGTTRPGPL 129
Query: 2134 PQQLLACSP----AWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQG 2189
Q+ L S A EA A + GA P T SP + + A G
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 2190 EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV 2249
P PP + P+ S E S E SP A P AG
Sbjct: 189 LPRPAPSARPRPPT-----------EGPRKSVSSASEHSTTEP---SPA-ARRRPSAGGG 233
Query: 2250 SPSVAVRATGLSSTPTGDEAQAG---RGLPG-------PDPQSRGA--PPHTNPDRM--- 2294
A R+ S+TP A++G RG P P P+ A PP P R
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 2295 ----PRGHSSYS-PSNTARLGHREGQAVTAVP---------TEPPTLQGAGPDSPACLEG 2340
P S + PS +A L + + A P P L P +P L+
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ- 352
Query: 2341 EMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRN 2400
P P TP + + + P + + L PS S + PQ+
Sbjct: 353 ------TLPSPPATPPSQATTSLGSPTLQATHSFL-------PSPPLSPLATPPPQAPPA 399
Query: 2401 ASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFR--SGPG 2458
+ Q P P A QAP P A F + P
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459
Query: 2459 LSRHKARKHRPHPGAPAEP-------------SPAALPAQQPLEPLA----QKCQPPRKK 2501
+S + P A P SP+A P Q PLA Q +PP +
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519
Query: 2502 SHRVS---------------GKERPNHSRGDPSHVTQPPPAQG----SKEVLRAPGSPHS 2542
++ G+ + S P PP Q + +L+ P SP +
Sbjct: 520 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579
Query: 2543 QQL-----HPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPS 2597
PP+P T S PR A P R P D
Sbjct: 580 SPTLQAPRRPPTP-----GPDTSVSGPRLTLALAP--GPPPPPSRSPSSTLSGP--DLAG 630
Query: 2598 HSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGP 2657
HS ++ +LRG E S ++ P A+++ P+ L+ G P
Sbjct: 631 HSSSATSTPE-ELRGYDSGPEGGAAASPPPDAELAACHP----AAWSRGPAPPLAFRGAP 685
Query: 2658 EADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPT 2717
A PP GPG +G + G A PG L PG G + G+
Sbjct: 686 GAPLPWPP---ATGPGSADGLCTIYE---TEGPESATPAPG--ALDPGPSPGTSGGKAAA 737
Query: 2718 GQ-KGASAR 2725
G GAS+R
Sbjct: 738 GAGAGASSR 746
Score = 42.7 bits (99), Expect = 0.007
Identities = 122/524 (23%), Positives = 167/524 (31%), Gaps = 96/524 (18%)
Query: 3424 GVRRPGAPGQKARAL--EGTLPSKRRRVAMPGSAPGPGEDR----PPPRGSSPILSEGSL 3477
G RPG GQK + E T+ + A SA G R P P SP ++ S
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 3478 PALLHLCSEVAPSTTKGWPETLE--RPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALA 3535
A T G P RP P P + S H + P PAA
Sbjct: 182 AA----------GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TTEPSPAA-- 224
Query: 3536 DGRGDCALDGALERPENEASPGSPGPLLQQAL--PLGASLPRPGARGQDAEGK-----RA 3588
R + G L+RP + + S PL A P PR A + K R
Sbjct: 225 --RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 3589 PLVFSGKRRAPGARG------------------RCAPDHFQEDHLLQKEKEVSSSHMVSE 3630
P V ++ A A G + P H ++++ ++
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
Query: 3631 GGPRG-----TFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELAR 3685
P T AT P+ +S + +T S P+ P AP LA
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402
Query: 3686 G------TENGMKPATPKAKPGPSS---------QGSGSPRPGTKTGGGSQPQPASGQLQ 3730
+ P +P A P P + Q SP P P PAS +
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPV- 460
Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGP---------KE 3781
S +AT P++ PS + P ++P A Q P P +
Sbjct: 461 SPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519
Query: 3782 KGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPS------RVLPTKPK 3835
+T + PA F + S P P TP QA P +V P+ P
Sbjct: 520 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579
Query: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKR 3879
+ PR PP+ P + RL A G P PP R
Sbjct: 580 SPTLQAPRRPPT----PGPDTSVSGPRLTLALAPGPP--PPPSR 617
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 105 bits (263), Expect = 7e-22
Identities = 310/1288 (24%), Positives = 388/1288 (30%), Gaps = 264/1288 (20%)
Query: 3 GERPRG-----APP--PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQA 55
G+ P+G PP P GD SPG P P + ++ P G + Q
Sbjct: 101 GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPT-----GPQNYSPQY 155
Query: 56 QAMELPEAQPRQARDGELKPPSLRGQ-APSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEG 114
+ ++ G P G P T G GSP +P + P P +
Sbjct: 156 DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPP 215
Query: 115 SPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLR-PGLPRTEAQP 173
PP +G + K P P E P PG P PG P +
Sbjct: 216 GPPG--AIGPSGPAGKDGESGRPGRP-------GERGLPGPPGIKGPAGIPGFPGMKGHR 266
Query: 174 AAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAP-GPPQSRGTS--PLQPGSYPEYQAS 230
+ + P + P P P G P RG P G+ A
Sbjct: 267 GFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGAR 326
Query: 231 GADSWP----PAAENSFPGA--------------NFGVPPAEPEPIPKG-----SRPG-- 265
G+D P P FPG+ + G P EP P+G PG
Sbjct: 327 GSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPP 386
Query: 266 ---GSPRGVSFQFP-----FPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEA 317
GSP G P P L GA P PA G G P
Sbjct: 387 GINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR 446
Query: 318 VGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKS 375
G A +P P G PG G N +G +PG A
Sbjct: 447 GERGEA-GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPA----------G 495
Query: 376 LTKILPERPPSAQDGLGSTRGP------------PSSLPQRHFPGQAYRASGVDTSPGPP 423
I E+ P+ + G GP P R PG G D PGPP
Sbjct: 496 PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSP-GGPGSDGKPGPP 554
Query: 424 DT--ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQR-------L 474
+ E PGPP P+ P +P P G A ++ G PG +
Sbjct: 555 GSQGESGRPGPPGPSGPR-GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613
Query: 475 CLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--GSQGALGTAGKTPGPRE 532
PQ P P P G + L LP G P G G G G AG P
Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673
Query: 533 KLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSE-- 590
K A + G P L G+ GA P + P G P + P E
Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRG-GAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERG 732
Query: 591 ---SPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP 647
SP P G + P P P+ GP+GP P E G+P
Sbjct: 733 GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPT-------GPIGPPGPAGQPGDKGEGGAP 785
Query: 648 -FPSPEPPHSLPTHY----QPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGL 702
P P P P PA FP G G E P E E G G+
Sbjct: 786 GLPGIAGPRGSPGERGETGPPGPA-GFPGAPGQNGEPGG---KGERGAPGEKGEGGPPGV 841
Query: 703 QGFP----RAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLA 758
G P A PP P R G A
Sbjct: 842 AGPPGGSGPAGPPGP------------------------------QGVKGERGSPGGPGA 871
Query: 759 RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLP 818
G + PGPPG P P G + + GKD P
Sbjct: 872 AGFPGARGLPGPPGSNGNPGPP--------------------GPSGSPGKDGP------- 904
Query: 819 SLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRG 878
P PA + + ++G + + P ++ G +G
Sbjct: 905 -------PGPAGNTGAPG--------SPGVSGPKGDAGQP----------GEKGSPGAQG 939
Query: 879 PSSGHPLKSKAGVTPES--KAPP--PLPAATPDPQ-----TPRPGDRGCPA-RGRPKTRS 928
P AG+T PP P P +P PQ + +PG G RG P +
Sbjct: 940 PPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG 999
Query: 929 L-GLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLG 987
L GLA T A GR G D +GS G G R P G
Sbjct: 1000 LPGLAGT---AGEPGRDGNPGS---------DGLPGRDGSPGGKGDRGENGSPGAPGAPG 1047
Query: 988 ERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWG 1047
PP P P ++ G R + P P A P +R + P + PR K G G
Sbjct: 1048 HPGPPGPVGPAGKS-GDRGESGPAGPAGAPGPAGSRGA-----PGPQGPRGDKGETGERG 1101
Query: 1048 KELILKIVQQKNRLREYDFASESEEDEQPPPRG-------PGFRGRRG----RGEKRKEV 1096
I F P P G PG G RG G K+
Sbjct: 1102 AAGI---------KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDG 1152
Query: 1097 ELTQG-PREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGP-SRSLETGA 1154
T G P P PR R E G +G+P +P +PG PGP P A GP + A
Sbjct: 1153 --TSGHPGPIGPPGPR-GNRGERGSEGSPGHPGQPG--PPGP---PGAPGPCCGGVGAAA 1204
Query: 1155 AAREGGPKCADRPSVAPKDPLQVPTNTE 1182
A GG K +P+ NT+
Sbjct: 1205 IAGIGGEKAGGFAPYYGDEPMDFKINTD 1232
Score = 97.1 bits (240), Expect = 3e-19
Identities = 326/1305 (24%), Positives = 384/1305 (29%), Gaps = 303/1305 (23%)
Query: 74 KPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTL 133
+PP+ GQ P G G P P P + PP GI S
Sbjct: 97 RPPN--GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPP-----GICES------ 143
Query: 134 DETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTS 193
P PQ + Q D G G GL
Sbjct: 144 --CPTGPQNYSPQYDSYDVKSGVAVG-----GL--------------------------- 169
Query: 194 TNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPA 253
Y P+ P P PGPP + G P PGS P YQ PG P+
Sbjct: 170 AGYPGPAGPPGP--PGPPGTSG-HPGSPGS-PGYQGP-------------PGEPGQAGPS 212
Query: 254 EPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313
P P P G+ P G + P G P P + G A G H+
Sbjct: 213 GP-PGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGR 271
Query: 314 PEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLH 373
E TG P + LP G PG + G PG +A +D
Sbjct: 272 NGEKGETG----APGLKGENGLPGENGAPGPMGPRG-APGERGRPGLPGAAGARGNDGAR 326
Query: 374 KSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP 433
S DG GPP + FPG A G G P + APG
Sbjct: 327 GS-------------DGQPGPPGPPGT---AGFPGSP-GAKGEVGPAGSPGSN-GAPGQR 368
Query: 434 PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTAR- 492
PQ P P PPG NG P + A +P L AR
Sbjct: 369 GEPGPQGHAGAQGP-PGPPG----------INGSPGGKGEM---GPAGIPGAPGLMGARG 414
Query: 493 -PSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK-----LPAVRSSQG---- 542
P P G L AG P G GA G PGPR + +P V ++G
Sbjct: 415 PPGPAGANGAPGLRGGAGEP----GKNGAKG----EPGPRGERGEAGIPGVPGAKGEDGK 466
Query: 543 -GSPALFTYNGMTDPGA-----QPLFFGVAQPQVSP--------HGTPSLPPPRVVGASP 588
GSP NG+ PGA P F G A P P G P PR P
Sbjct: 467 DGSPGEPGANGL--PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEP 524
Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANP--SSEESQLPGPLGPSAFFHPPTHPQETGS 646
+P G S P S P S ES PGP GPS P P G
Sbjct: 525 GRDGVPG-GPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG---PRGQPGVMG- 579
Query: 647 PFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFP 706
FP P+ P P P G G E P GP G GG +G
Sbjct: 580 -FPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNG-----ETGPQGPPGP-TGPGGDKGDT 632
Query: 707 RAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQR 766
P P G ++G
Sbjct: 633 GPPGPQGLQGLP-----------------------------------GTGGPPGENGKPG 657
Query: 767 SPGPPGLPSPPAAPRVPADAHA-------------GLLSHAKTFLLAGDAQAEGKDDPLR 813
PGP G P AP DA A GL A G A G P
Sbjct: 658 EPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPG 717
Query: 814 TGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEP 873
P L P + L + G + + P D V + P
Sbjct: 718 AAGTPGLQGMP-------------GERGGLGSPGPKGDKGEPGGPGADG----VPGKDGP 760
Query: 874 SGPRGP-----SSGHPLKSKAGVTP--------------ESKAPPPLPAATPDP--QTPR 912
GP GP +G P G P + PP PA P Q
Sbjct: 761 RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE 820
Query: 913 PGDRGCPARGRPKTRSLGLAPTEADAP-SQGRQQRRGKQ-LKLFRKDLDSGGAAEGSGSG 970
PG +G RG P + G P A P G G Q +K R GAA G+
Sbjct: 821 PGGKG--ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGAR 878
Query: 971 G-----GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSS 1025
G G + P + G+ PP P T APGS P+ A P E S
Sbjct: 879 GLPGPPGSNGNPGPPGPSGSPGKDGPPGP-AGNTGAPGSPGVSGPK--GDAGQPGEKGSP 935
Query: 1026 RRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRG-PGFR 1084
+ P P GA G + P PRG PG +
Sbjct: 936 GAQGPPGAPGPLGIAGITGARGL---------------------AGPPGMPGPRGSPGPQ 974
Query: 1085 GRRGRGEKRKEVELT--QGPREDEPQKPRKAARQEAGGDGAPANPEEPG--GSRPGPGRS 1140
G +G K L+ +GP + E G DG P + PG GS G G
Sbjct: 975 GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034
Query: 1141 PQARGPSRSLETGAAAREGGP-------KCADRPSVAPKDPLQVPTNTETSEETRPSLDF 1193
+ P GA G P K DR P P P P
Sbjct: 1035 GENGSPG---APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAP--GPAGSRGAPGPQG 1089
Query: 1194 PQEAKEPETAEESAPDSTEFTEALRSPPA----ACAGEMGA--SPGLLIPEQP-----PP 1242
P+ K ET E A +P A AG+ GA SPG P P PP
Sbjct: 1090 PRGDK-GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP 1148
Query: 1243 SRHDT----GTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283
+ T G P G N GS +PG G PG AP
Sbjct: 1149 GKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAP 1193
Score = 92.8 bits (229), Expect = 6e-18
Identities = 332/1377 (24%), Positives = 411/1377 (29%), Gaps = 354/1377 (25%)
Query: 140 PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSP 199
P + P PQGP G P PG+P P P
Sbjct: 91 PPTAPTRPPNGQGPQGP-KGDPGPPGIPGRNGDPGI-----------------------P 126
Query: 200 SATPRPPAPGPPQSRGTSPLQPGSY-PEYQASGADSWPPAAENS-FPGANFGVPPAEPEP 257
P +PGPP + P P +Y P+Y + S + +PG PP P P
Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGP--AGPPGPPGP 184
Query: 258 IPKGSRPGGSPRGVSFQFP--FPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPE 315
PG SP +Q P P G S P P G +GP + P
Sbjct: 185 PGTSGHPG-SPGSPGYQGPPGEPGQAGPSGPPGPPGAIG---PSGPAGKDGESGRPGRPG 240
Query: 316 EAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAPRPFSDSLH 373
E GP P P+ +P + G G G + + G +PG
Sbjct: 241 ERGLPGP----PGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGL------------- 283
Query: 374 KSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYR-----ASGVDTSPGPPDTELA 428
++GL G P + R PG+ R A+G + G ++
Sbjct: 284 ------------KGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD-G 330
Query: 429 APGPPPARLPQLWDPTAAPYPTPPG--GPLAATRSMFFNGQPSPGQR-LCLPQS-APLPW 484
PGPP P A +P PG G + S NG +PGQR PQ A
Sbjct: 331 QPGPPGP-------PGTAGFPGSPGAKGEVGPAGSPGSNG--APGQRGEPGPQGHAGAQG 381
Query: 485 PQVLPTARPSPHGMEMLSRLPFP-------AGGPEWQGGSQGALGTAGKT---------- 527
P P SP G + P A GP G+ GA G G
Sbjct: 382 PPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKG 441
Query: 528 -PGPREK-----LPAVRSSQG-----GSPALFTYNGMTDPGAQ-----PLFFGVAQPQVS 571
PGPR + +P V ++G GSP NG+ PGA P F G A P
Sbjct: 442 EPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL--PGAAGERGAPGFRGPAGPNGI 499
Query: 572 P--------HGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623
P G P PR P +P + M SP P S+
Sbjct: 500 PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP---------GMRGMPGSPGGPGSDGK 550
Query: 624 QLPGPLGPSAFFHPPTHPQETGSPFP-SPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAF 682
PGP G E+G P P P P P FP P GA G
Sbjct: 551 --PGPPGSQG---------ESGRPGPPGPSGPRGQPG------VMGFPGPKGNDGAPGKN 593
Query: 683 QCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSS 742
P G+ G G P+ PP PT D+ D
Sbjct: 594 GERGGPGGPGPQGPPGKNGETG-PQGPPG-PT------GPGGDKGDT------------- 632
Query: 743 LAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGD 802
G + G + GPPG P P DA A K GD
Sbjct: 633 -----------GPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK-----GD 676
Query: 803 AQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDS 862
A A G+ P P LA P L G
Sbjct: 677 AGAPGERGP------PGLAGAP----------------------GLRG------------ 696
Query: 863 SFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARG 922
+GP GP G G PP A TP Q PG+RG
Sbjct: 697 ----------GAGPPGPEGGKGAAGPPG--------PPGAAGTPGLQG-MPGERGGLGSP 737
Query: 923 RPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR--- 979
PK AD G+ RG + G A G G G A GL
Sbjct: 738 GPKGDKGEPGGPGADGVP-GKDGPRGPT-----GPIGPPGPAGQPGDKGEGGAPGLPGIA 791
Query: 980 -PRRNDG-LGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPR 1037
PR + G GE PP P APG +P + R A P E P P
Sbjct: 792 GPRGSPGERGETGPPGPAG-FPGAPGQNGEPGGKGERGA--PGEKGEGGP---PGVAGPP 845
Query: 1038 KRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPG---FRGRRGRGEKRK 1094
G G + + + E+ P GPG F G RG
Sbjct: 846 GGSGPAGPPGPQGV--------------------KGERGSPGGPGAAGFPGARGLPGPPG 885
Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPG----GSRPGPGRSPQARGPSRSL 1150
GP + AG GAP +P G +PG SP A+GP +
Sbjct: 886 S-NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAP 944
Query: 1151 E-------TGAAAREG-----GPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAK 1198
TGA G GP+ + P + + N + E P PQ
Sbjct: 945 GPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG---PQGLP 1001
Query: 1199 E-PETAEESAPDSTEFTEAL--RSPPAACAGEMGAS-----------PGLLIPEQPPPSR 1244
TA E D ++ L R G+ G + PG P P
Sbjct: 1002 GLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKS 1061
Query: 1245 HDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVA 1304
D G P+G P GS P GP G + + A G P
Sbjct: 1062 GDRGESGPAGPAGAPGPAGSRGAP-------GPQGPRGDKGETGERGAAGIKGHRGFP-G 1113
Query: 1305 NPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGV--PVAKKG----PQPYSSPHSELFLG 1358
NP + P P+ I S G PAG R P+G P K G P P P G
Sbjct: 1114 NPGAPGSPGPAGQQGAIGSPG--PAG-PRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRG 1170
Query: 1359 PKDLAGCFLEELHPKPSARDAPPASSSCLCQ----------DGEDAGSLEPQLPRSP 1405
+ G HP PP + C GE AG P P
Sbjct: 1171 ERGSEG---SPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEP 1224
Score = 81.3 bits (199), Expect = 2e-14
Identities = 208/834 (24%), Positives = 252/834 (30%), Gaps = 189/834 (22%)
Query: 1 MPGER-------PRGAPP----PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAR 49
+PGE PRGAP P + G R + G QP P T G+
Sbjct: 289 LPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPG-PPGPPGTAGFPGSP 347
Query: 50 EAGGQAQAMELPEAQPRQARDGELKPPSLRG-QAPSSTPGKRGSP--------------- 93
A G+ P + + GE P G Q P PG GSP
Sbjct: 348 GAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407
Query: 94 -----QTPPGRSPLQAPSRLAGRA--------EGSPPQRY------ILGIASSRTKPTLD 134
+ PPG + L G A +G P R I G+ ++ + D
Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467
Query: 135 ETPENPQLEAAQLPEVDTPQG-PGTGAPLRPGLPRTEAQPAAEE-----LGFHRCFQEPP 188
+P P A LP +G PG P P E PA E G EP
Sbjct: 468 GSPGEPG--ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525
Query: 189 SSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANF 248
P P +PG P S G P PGS E G PP P
Sbjct: 526 RDGVPGG---PGMRGMPGSPGGPGSDG-KPGPPGSQGESGRPG----PPG-----PSGPR 572
Query: 249 GVPPAEPEPIPKGS--RPG-----GSPRGVSFQFPFPALHGASTK---PFPADVAGHAFT 298
G P P PKG+ PG G P G Q P P +G + P P G
Sbjct: 573 GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP-PGKNGETGPQGPPGPTGPGGDKGD 631
Query: 299 NGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQPGGLNRHSDLSGALSS 357
GP PQG G P P +P P G PGG + G
Sbjct: 632 TGP-----PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG-DAGAPGERGP 685
Query: 358 PGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTR--GPPSSLPQRHFPGQAYRASG 415
PG A AP + PP + G G+ GPP + G G
Sbjct: 686 PGLA-GAPGLRGGA-----------GPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733
Query: 416 VDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLC 475
+ SPGP + GP +P P P P GP G P
Sbjct: 734 LG-SPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG------ 786
Query: 476 LPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLP 535
LP A P P G GP G GA G G+ G E+
Sbjct: 787 LPGIAG-------PRGSPGERGET----------GPPGPAGFPGAPGQNGEPGGKGERGA 829
Query: 536 AVRSSQGGSPALFTYNGMTDPGAQPLFFGV-----------------AQPQVSPHGTPSL 578
+GG P + G + P P GV A+ P G+
Sbjct: 830 PGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGN 889
Query: 579 PPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-------LPGPL-- 629
P P SP + P PA NT +S P + S PGPL
Sbjct: 890 PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949
Query: 630 ----GPSAFFHPPTHPQETGSPFP-------------------SPEPPHSLP--THYQPE 664
G PP P GSP P P P LP E
Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009
Query: 665 PAKAFPFPADGL-GAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP----PPYP 713
P + +DGL G +G+ P + G G G P AP PP P
Sbjct: 1010 PGRDGNPGSDGLPGRDGS---------PGGKGDRGENGSPGAPGAPGHPGPPGP 1054
Score = 74.7 bits (182), Expect = 2e-12
Identities = 217/902 (24%), Positives = 274/902 (30%), Gaps = 155/902 (17%)
Query: 649 PSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRA 708
P+PE P P+P A P +G G +G P + G G G P +
Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134
Query: 709 PPP------YPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKD 762
P P PT + S D DV + LA + G
Sbjct: 135 PGPPGICESCPTGPQNYSP-QYDSYDV-----KSGVAVGGLAGYPGPAGPPGPPGPPGTS 188
Query: 763 GHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAA 822
GH SPG PG PP P AG G + GKD P
Sbjct: 189 GHPGSPGSPGYQGPPGEP-----GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243
Query: 823 TPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSG 882
P P + G + D +G +G +
Sbjct: 244 LPGPPGIKG-------------PAGIPGFPGMKGHRGFDGR----------NGEKGETGA 280
Query: 883 HPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCP-ARGRPKTRSLGLAPTEADAPSQ 941
LK + G+ E+ AP P+ + RPG G ARG R P P
Sbjct: 281 PGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT 340
Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR--PRRNDGLGERPPPRPRRPRT 999
F + G +GS G A G R P G + PP P
Sbjct: 341 AG----------FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING 390
Query: 1000 QAPGSRADPAPR-VPRAAAL--------PEETRSSRRRRLPPRKDPRKRKARG-----GA 1045
+PG + + P +P A L P + R +P K A+G G
Sbjct: 391 -SPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLR-GGAGEPGKNGAKGEPGPRGE 448
Query: 1046 WGKELILKIVQQKNRLREYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQG 1101
G+ I + K + E + P G PGFRG G E +G
Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE----KG 504
Query: 1102 PREDE----PQKPRKAARQEAGGDGAPANPEEPG--GSRPGPGRSPQARGPSRSLETGAA 1155
P + P PR AA E G DG P P G GS GPG + P E+G
Sbjct: 505 PAGERGAPGPAGPRGAAG-EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP 563
Query: 1156 AREGGPKCADRPSV----APKDPLQVPTNTETSEETRPSLDFPQ--EAKEPETAEESAPD 1209
G +P V PK P + E P PQ K ET + P
Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPG--KNGERGGPGGPGPQGPPGKNGETGPQGPPG 621
Query: 1210 STEFTEALRSPPAACAGEMGAS-----PGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGS 1264
T P G+ G GL PP G P P G G
Sbjct: 622 PTG--------PGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673
Query: 1265 SPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLA-PVANPSSTACPKPSVLSSKISS 1323
G G PG AP PP + G+ A P P + P + +
Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733
Query: 1324 FGC--------DPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPS 1375
G +P G D GVP K GP+ + P +GP AG P
Sbjct: 734 LGSPGPKGDKGEPGGPGAD--GVP-GKDGPRGPTGP-----IGPPGPAG------QPGDK 779
Query: 1376 ARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGT-AETEPGRAASPPTLESSSLFPDLPVD 1434
P AG PR PG ET P A FP P
Sbjct: 780 GEGGAPGLPGI-------AG------PRGSPGERGETGPPGPAG---------FPGAPGQ 817
Query: 1435 RFDPPLYGSLSA--NRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLP--SHFPDL 1490
+P G A + G P A PP + P+ PP P + E SP P + FP
Sbjct: 818 NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA 877
Query: 1491 SG 1492
G
Sbjct: 878 RG 879
Score = 73.2 bits (178), Expect = 5e-12
Identities = 232/966 (24%), Positives = 302/966 (31%), Gaps = 201/966 (20%)
Query: 1622 VQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQ 1681
+ G PGG + PG L+ P P GAN P + GA + G
Sbjct: 388 INGSPGGKGEMGPAGIPGAPGLMGAR-------GPPGPAGANG--APGLRGGAGEPGKNG 438
Query: 1682 AEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLP 1741
A+G+ PGP+ + G E P + ED P
Sbjct: 439 AKGE---------------PGPRGERG---------EAGIP----GVPGAKGEDGKDGSP 470
Query: 1742 CEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSH 1801
E LP G A + RGAP F PA P+ G+ P + P A P
Sbjct: 471 GEPGANGLP--GAAGE--RGAPG---FRGPA---GPN-GIPGEKGPAGERGAPGPAGPRG 519
Query: 1802 AA--QGHSAGRAGGHLHPTAGRPGFEGNEFAPA-----GASSLTAPRGREAWLVPVPSPA 1854
AA G G + G PG G++ P G S P G P P
Sbjct: 520 AAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG---PRGQPG 576
Query: 1855 CVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQ----ELTPAAQS----PPR 1906
+ P P + PGP K+G G Q P PP
Sbjct: 577 VMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPP- 635
Query: 1907 VNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQG 1966
P GL+G GG G PG P G + A G G G A
Sbjct: 636 -GPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL 694
Query: 1967 QGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEP 2026
+G A PE G G +P G + KG + A+
Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG-GPGADG 753
Query: 2027 TPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACA 2086
P P + + + G +G +PGL P +A P S G+
Sbjct: 754 VPGKDGPRGPTGPIGPPGPAGQPGDKG----EGGAPGL--PGIA---GPRGSPGERGETG 804
Query: 2087 -PSPTSAAHMPCSLGP--------LPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137
P P P G P E P G GG PA PPGPQ +
Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG-----PPGPQGV 859
Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDP 2197
G A GA P PP +P P + GSP +D
Sbjct: 860 K------GERGSPGGPGAAGFPGARGLP-GPPGSNGNPGPPGPS---------GSPGKDG 903
Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257
P G+ A P + P+ + PG SP GA P A
Sbjct: 904 PPGPAGNTGA---------PGSPGVSGPKGDAGQ-----PGEKGSP---GAQGPPGAPGP 946
Query: 2258 TGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRG--HSSYSPSNTARLGHREG 2314
G++ TG AG G+PGP RG+P P+G S P G R
Sbjct: 947 LGIAGI-TGARGLAGPPGMPGP----RGSPG-------PQGVKGESGKPGANGLSGER-- 992
Query: 2315 QAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTG 2374
GP P L G GT+ + D G G+ +P
Sbjct: 993 ----------------GPPGPQGLPGLAGTAGEPGRD------GNPGSDGLP-------- 1022
Query: 2375 LGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTEN-- 2432
GR +P ++ SP + H P G P+GP K RG + PA
Sbjct: 1023 ---GRDGSPGGKGDRGENGSPGAPGAPGHPGPPG-PVGPAG-KSGDRG-ESGPAGPAGAP 1076
Query: 2433 ---GQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA----ALPAQ 2485
G P GP + R G+ H R +PGAP P PA A+ +
Sbjct: 1077 GPAGSRGAPGPQGP-RGDKGETGERGAAGIKGH--RGFPGNPGAPGSPGPAGQQGAIGSP 1133
Query: 2486 QPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSP-HSQQ 2544
P P + SG + + G P + PP +G++ + GSP H Q
Sbjct: 1134 GPAGP---------RGPVGPSGPPGKDGTSGHPGPI-GPPGPRGNRGERGSEGSPGHPGQ 1183
Query: 2545 LHPPSP 2550
PP P
Sbjct: 1184 PGPPGP 1189
Score = 68.9 bits (167), Expect = 9e-11
Identities = 259/1075 (24%), Positives = 333/1075 (30%), Gaps = 206/1075 (19%)
Query: 480 APLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG-----GSQGALGTAGKTPGPREKL 534
A P P PT P+ G + P P G P G G G+ G+ G PG E
Sbjct: 86 AVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGP-PGICESC 144
Query: 535 PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLP 594
P Q SP +Y+ + GVA ++ + P+ PP P P
Sbjct: 145 PT--GPQNYSPQYDSYDVKS---------GVAVGGLAGYPGPAGPP------GPPGPPGT 187
Query: 595 SPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHP------PTHPQETGSPF 648
S + GS P A PS PG +GPS P P E G P
Sbjct: 188 SGHPGSPGSPGYQGPPGEPGQAGPSGPPGP-PGAIGPSGPAGKDGESGRPGRPGERGLPG 246
Query: 649 PSP-EPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHE-------GP----- 695
P + P +P + + F G GA E P E GP
Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306
Query: 696 EVGRGGLQGF---------------PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNY 740
E GR GL G P P P T F S + ++
Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGP----------- 355
Query: 741 SSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLA 800
A G GH + GPPG P +P G + A
Sbjct: 356 ---AGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSP-----GGKGEMGPAGIPGAP 407
Query: 801 GDAQAEGKDDPLRTGFLPSL----------AATPFPLPASDLDMEDDAKLDSLITEALNG 850
G A G P P L A P P + +A + + G
Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE---RGEAGIPGV--PGAKG 462
Query: 851 MEYQSDNP-EIDSSFIDVFADEEPS-GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDP 908
+ + +P E ++ + A E + G RGP+ + + + G E AP P A P
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP---AGPRG 519
Query: 909 QTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFR------------- 955
PG G P G P R G+ + S G+ G Q + R
Sbjct: 520 AAGEPGRDGVP--GGPGMR--GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575
Query: 956 --------KDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRAD 1007
K D G G GG P +N G + PP P P G + D
Sbjct: 576 GVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG----GDKGD 631
Query: 1008 PAPRVPRAA-ALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKN------- 1059
P P+ LP P P+ GA G + ++
Sbjct: 632 TGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGA 691
Query: 1060 ---RLREYDFASESEEDEQPPPRGPGFRGRRG-RGEKRKEVEL-TQGPREDEPQKPRKAA 1114
R E + PP PG G G +G + L + GP+ D+ + A
Sbjct: 692 PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751
Query: 1115 RQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLET-GAAAREGGPKCADRPSVAPKD 1173
G DG P P P G PGP P +G + G A G P +R P
Sbjct: 752 DGVPGKDG-PRGPTGPIGP-PGPAGQPGDKGEGGAPGLPGIAGPRGSP--GERGETGPPG 807
Query: 1174 PLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSP-----PAACAGEM 1228
P P + E E P E P P P GE
Sbjct: 808 PAGFPGAPGQNGEPGGK----GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863
Query: 1229 GASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNS 1288
G SPG P +R G P P GS N P G S +PG G G T AP S
Sbjct: 864 G-SPGGPGAAGFPGAR---GLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGV 919
Query: 1289 KDP--PARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQ 1346
P A QPGE +P A P P ++ + G AG P G+P + P
Sbjct: 920 SGPKGDAGQPGEKGSPGAQ-GPPGAPGPLGIAGITGARGL--AG----PPGMPGPRGSPG 972
Query: 1347 PYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPP 1406
P G K +G KP A +G P P+ P
Sbjct: 973 PQ---------GVKGESG--------KPGANGL--------------SGERGPPGPQGLP 1001
Query: 1407 GTAET--EPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADP 1459
G A T EPGR +P + LP P G N G P A P
Sbjct: 1002 GLAGTAGEPGRDGNPGS-------DGLPGRDGSPGGKGDRGENGSPGAPGAPGHP 1049
Score = 67.0 bits (162), Expect = 3e-10
Identities = 264/1160 (22%), Positives = 352/1160 (30%), Gaps = 233/1160 (20%)
Query: 1119 GGDGAPANPEEPGGSRP-GPGRSPQARGPS----RSLETGAAAREGGPKCADRPSVAPKD 1173
G G P EPG + P GP P A GPS + E+G R G P + K
Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGI--KG 252
Query: 1174 PLQVPTNTETSEETRPSLDFPQ-------EAKEPETAEESAPDSTEFTEALRSPPAACAG 1226
P +P FP + + E E AP G
Sbjct: 253 PAGIP-------------GFPGMKGHRGFDGRNGEKGETGAPGL--------KGENGLPG 291
Query: 1227 EMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSH 1286
E GA PG + P P R G P +G+ N GS PG G PG P S
Sbjct: 292 ENGA-PGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP---GPPGTAGFPGSP 347
Query: 1287 NSKDPPARQPGEFLAPVANPSSTACP----KPSVLSSKISSFGCDPAGFNRDPLGVPVAK 1342
+K GE + P +P S P +P + P G N G P K
Sbjct: 348 GAK-------GE-VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN----GSPGGK 395
Query: 1343 KGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLP 1402
P P + +G + P P+ + P + G++ EP P
Sbjct: 396 GEMGPAGIPGAPGLMGARG---------PPGPAGANGAPGLRGGAGEPGKNGAKGEPG-P 445
Query: 1403 RSPPGTA--------ETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF 1454
R G A + E G+ SP ++ L P +R P G N G+P
Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL-PGAAGERGAPGFRGPAGPN---GIPG 501
Query: 1455 ACADPPQKTVPSDPPYPSFLLLEEVSPMLPSH-----FPDLSGGKVLSKTCPPERTVVPG 1509
++ P P P E +P P GG P +
Sbjct: 502 EKGPAGERGAPG-PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560
Query: 1510 AAPSLPG-KGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGR 1568
P PG G +M K GAP + E G
Sbjct: 561 GRPGPPGPSGPRGQPGVMG-------------------FPGPKGNDGAPGKNGERGGPG- 600
Query: 1569 VELGTGTE-PPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPG 1627
G G + PP + P T D G + +QG PG
Sbjct: 601 ---GPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP------------QGLQGLPG 645
Query: 1628 GTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSR 1687
P + PG P + D +GAP +P G P ++ G G +
Sbjct: 646 TGGPPGENGKPGE----PGPKGD--AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAG 699
Query: 1688 PPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSF-----PKNKEAASSQESEDSLRLLPC 1742
PP + PGP AG+ E PK + D + P
Sbjct: 700 PPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV---PG 756
Query: 1743 EQ--RG--GFLPEPGTADQP----HRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWP 1794
+ RG G + PG A QP GAP P +G+ PP A +P
Sbjct: 757 KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE----RGETGPPGPAGFP 812
Query: 1795 FGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPA 1854
GA + G R G PG G P G S P P P
Sbjct: 813 -GAPGQNGEPGGKGERGAPGEKGEGGPPGVAG----PPGGSGPAGP----------PGPQ 857
Query: 1855 CVSNTHPSRRSQDPALSPPIRQLQ----------LPGPGVAKSKDGILGLQELTPAAQSP 1904
V S A P R L PGP + KDG G T A SP
Sbjct: 858 GVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSP 917
Query: 1905 PRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAG--HQLGLE----ADGHWGLL 1958
P G G E G G+PG + + + G G+ + G G+
Sbjct: 918 GVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK 977
Query: 1959 GQAEKTQGQGTANQLQPENGVS-PG--GTDNHASVNASPKTALTGPTEGAVLLEKCKGSR 2015
G++ K G + + P PG GT + +P + +G+ + +G
Sbjct: 978 GESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN 1037
Query: 2016 AAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSP 2075
+ A P PP P G G++ +R S P
Sbjct: 1038 GSPG-APGAPGHPGPPGP---------------VGPAGKSGDRGES------------GP 1069
Query: 2076 APSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQ--LPASPSCRDPPG 2133
A G AP P + P G PR D + R G+ G P +P PG
Sbjct: 1070 AGPAG-----APGPAGSRGAPGPQG--PRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG 1122
Query: 2134 P--QQLLACSPAWA----PLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLL 2187
P QQ SP A P+ + G T P+ PP + +
Sbjct: 1123 PAGQQGAIGSPGPAGPRGPVGPS-GPPGKDGTSGHPGPIGPPGPRGNRGE---------R 1172
Query: 2188 QGEGSPLEDPSSWPPGSVSA 2207
EGSP PPG A
Sbjct: 1173 GSEGSPGHPGQPGPPGPPGA 1192
Score = 65.9 bits (159), Expect = 8e-10
Identities = 290/1235 (23%), Positives = 372/1235 (30%), Gaps = 247/1235 (20%)
Query: 1683 EGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQEL-SFPKNKEAASSQESEDSLRLLP 1741
+GD PP +P + PG GS P S P + S Q DS +
Sbjct: 108 KGDPGPPG---IPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQY--DSYDVKS 162
Query: 1742 CEQRGGFLPEPGTADQPHRGAPA-----PEAFGSPAVHLAPDLAFQGDGAPPLDATWPFG 1796
GG PG A P P P + GSP P Q + P G
Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG 222
Query: 1797 ASPSHAAQGHSA--GRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGR----------- 1843
S G S GR G P G PG +G PAG +G
Sbjct: 223 PSGPAGKDGESGRPGRPGERGLP--GPPGIKG----PAGIPGFPGMKGHRGFDGRNGEKG 276
Query: 1844 EAWLVPVPSPACVSNTHPSRRSQDPALSPPIR-QLQLPGPGVAKSKDGILGLQELTPAAQ 1902
E + + + + P +P R + LPG A+ DG G + P
Sbjct: 277 ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG-SDGQPGPP 335
Query: 1903 SPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAE 1962
PP +G G G+V + GS G P GH G G+ G
Sbjct: 336 GPP--GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPG 393
Query: 1963 KTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQE 2022
G A + G A N +P L G A +
Sbjct: 394 GKGEMGPAGIPGAPGLMGARGPPGPAGANGAP--GLRG--------------GAGEPGKN 437
Query: 2023 EAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDL 2082
A+ P P E+ + A G +G E PG N A G+ AP
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGE----PGANGLPGAAGERGAPGF--- 490
Query: 2083 AACAPSPTSAAHMPCSLGPL-PREDPLTSPSRAQGGLGGQ--LPASPSCRDPPGPQQLLA 2139
P +P GP R P + R G G+ +P P R PG
Sbjct: 491 ----RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPG------ 540
Query: 2140 CSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSS 2199
SP +DG + E PP P P+ G P
Sbjct: 541 -SPGG---PGSDGKPGPPGSQGESGRPGPP----GPSGPR-----------GQPGVMGFP 581
Query: 2200 WPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATG 2259
P G+ A P + + PG P G P TG
Sbjct: 582 GPKGNDGA-----------------PGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG 624
Query: 2260 LSSTPTGDEAQAG-------RGLPGPDPQSRGAPPHTN---PDRMPRGHSSY--SPSNTA 2307
P GD+ G +GLPG G PP N + P+G + +P
Sbjct: 625 ----PGGDKGDTGPPGPQGLQGLPG-----TGGPPGENGKPGEPGPKGDAGAPGAPGGKG 675
Query: 2308 RLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPR 2367
G + + P GAGP P EG G + PG P G +G +
Sbjct: 676 DAGAPGERGPPGLAGAPGLRGGAGPPGP---EGGKGAAG----PPGPP--GAAGTPGLQG 726
Query: 2368 VTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQG--DPLGPQDLKQRSRGYKK 2425
+ GLG +P + P + P+G P+GP
Sbjct: 727 MPGERGGLG-----SPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPG---------- 771
Query: 2426 KPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQ 2485
PA + +G AP P A R PG G P PA P
Sbjct: 772 -PAGQPGDKGEGGAPGLP-----GIAGPRGSPG-----------ERGETGPPGPAGFPGA 814
Query: 2486 QPLEPLAQKCQPPRKKSHRVSGKE---RPNHSRGDP--SHVTQPPPAQGSKEVLRAPGS- 2539
Q +P K G++ P G P S PP QG K +PG
Sbjct: 815 P-----GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869
Query: 2540 -----PHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVD 2594
P ++ L P + P+ P D P G P V
Sbjct: 870 GAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD-------GPPGPAGNTGA--PGSPGVS 920
Query: 2595 SPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAAS--PSHCLS 2652
P G+ +K G + + P+ I+ RG P M S P
Sbjct: 921 GPKGDAGQPGEKGSP--GAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKG 978
Query: 2653 VEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAAL 2712
G P A+G R GP + G A T AGE G PG L PGR DG+
Sbjct: 979 ESGKPGANGLSGER-GPPGPQGLPGLAGT------AGEPGRDGNPGSDGL-PGR-DGSPG 1029
Query: 2713 GEQPTGQKGA-SARGFWG-PRETKALGVCKESGSE-------PAEDSSRAHSRSEEGVWE 2763
G+ G+ G+ A G G P +G +SG PA A SR G
Sbjct: 1030 GKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG--- 1086
Query: 2764 ENTPPLGPLGFP-ETSSSPADSTTSSCLQGLPDNPDTQG--------------GVQGPEG 2808
P GP G ET A +G P NP G G GP G
Sbjct: 1087 ----PQGPRGDKGETGERGAAGIKGH--RGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRG 1140
Query: 2809 PTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTR 2843
P SG KD S + PPG R R
Sbjct: 1141 PV-GPSGPPGKDGTSGHPGPIG-----PPGPRGNR 1169
Score = 63.2 bits (152), Expect = 5e-09
Identities = 107/414 (25%), Positives = 146/414 (35%), Gaps = 66/414 (15%)
Query: 3428 PGAPGQKARAL---EGTLPSKRRRVAMPGSAPGPGEDRPP-PRGSSPILSEGSLPALLHL 3483
PGAPGQ E P ++ PG A PG P P G + E P
Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG---- 867
Query: 3484 CSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNH--QECPPPSL----SPFPAALADG 3537
P G+P P P ++ G PS ++ PP +P ++
Sbjct: 868 ----GPGAA-GFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922
Query: 3538 RGDCALDGALERPENEASPGSPGPLLQQAL--------PLGASLPR--PGARGQDAE-GK 3586
+GD G P + PG+PGPL + P G PR PG +G E GK
Sbjct: 923 KGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK 982
Query: 3587 RAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA 3646
SG+R PG +G ++ +G P G P
Sbjct: 983 PGANGLSGERGPPGPQGLPG-------------LAGTAGEPGRDGNPGSDGLPGRDGSPG 1029
Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGTENGMKPATPKAKPGPS-S 3704
G DR +P A P HP G + P G+ E+G PA P PGP+ S
Sbjct: 1030 G----KGDRGENGSPG-APGAPGHPGPP-GPVGPAGKSGDRGESG--PAGPAGAPGPAGS 1081
Query: 3705 QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG 3764
+G+ P+ G + + A+G FP AP P A +
Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAG--------IKGHRGFPGNPGAPGS-PGPAGQQGAIGS 1132
Query: 3765 PREAGEQGPHGSLGPKEKGESSTKRKKGQV--PGPARSESVGSFGRAPSAPDKP 3816
P AG +GP G GP G+ T G + PGP + +P P +P
Sbjct: 1133 PGPAGPRGPVGPSGP--PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184
Score = 60.5 bits (145), Expect = 3e-08
Identities = 126/515 (24%), Positives = 154/515 (29%), Gaps = 75/515 (14%)
Query: 3415 GGRQPFAFRGVRRPGAPG-QKARALEGTL-----PSKRRRVAMPGSAPGPGEDRPPPRGS 3468
GG+ G+ PGAPG AR G P R PG GE P PRG
Sbjct: 393 GGKGEMGPAGI--PGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE--PGPRGE 448
Query: 3469 SPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLS 3528
E +P + E + G P P G P+ P
Sbjct: 449 R---GEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEK-- 503
Query: 3529 PFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLG-ASLPRPGARGQDAE-GK 3586
PA G GA P + PG PG P G S +PG G E G+
Sbjct: 504 -GPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGR 562
Query: 3587 RAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA 3646
P SG R PG G P K + + GGP G +G K
Sbjct: 563 PGPPGPSGPRGQPGVMGFPGP----------KGNDGAPGKNGERGGPGGPGPQGPPGKNG 612
Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA----PGELARGTENGMK-----PATPK 3697
K P P+ G PGE + E G K P P
Sbjct: 613 ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG 672
Query: 3698 AKPGPSSQGSGSP-----RPGTKTGGGSQPQPASGQLQSE------TATTPAKPSFPSR- 3745
K + G P PG + GG P P G+ + A TP P
Sbjct: 673 GKGDAGAPGERGPPGLAGAPGLR-GGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGER 731
Query: 3746 ----SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPG-PARS 3800
SP P+ P + G +GP G +GP + +G PG P +
Sbjct: 732 GGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791
Query: 3801 ESVGSFGR----APSAPDKPPRTPRKQATP----SRVLPTKP----------KPNSQNKP 3842
GS G P P P P + P R P + P
Sbjct: 792 GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPA 851
Query: 3843 RPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPP 3877
PP + K E G G FP R L PP
Sbjct: 852 GPPGPQGVKGERGSPGGPGAAG--FPGARGLPGPP 884
Score = 58.9 bits (141), Expect = 9e-08
Identities = 121/501 (24%), Positives = 164/501 (32%), Gaps = 92/501 (18%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPG------SAPGPGEDRPPPRGSSPILSEGSLPALL 3481
PG PG R + +P + PG S P ++ P S + S ++ L
Sbjct: 111 PGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLA 170
Query: 3482 HLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDC 3541
P G P T P P + +G P PS P P G
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQG---PPGEPGQAGPSGPPGPPGAIGPSGPA 227
Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR-PGARG-QDAEGKRAPLVFSGKRRAP 3599
DG RP G PGP + A +P PG +G + +G+ G+ AP
Sbjct: 228 GKDGESGRPGRPGERGLPGP---PGIKGPAGIPGFPGMKGHRGFDGRNGE---KGETGAP 281
Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGT-FHKGSATKPAGCQSSSKDRSAA 3658
G +G ++ L E GPRG +G P + D +
Sbjct: 282 GLKG---------ENGLPGENGAPGPM-----GPRGAPGERGRPGLPGAAGARGNDGARG 327
Query: 3659 ST-------PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPR 3711
S P FP P A G + P G+ + +PGP
Sbjct: 328 SDGQPGPPGPPGTAGFPGSP-GAKGEVGPA----GSPGSNGAPGQRGEPGPQGHAGAQGP 382
Query: 3712 PGT-----KTGGGSQPQPAS--GQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG 3764
PG GG + PA G A P P+ + +P R A K+ KG
Sbjct: 383 PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPG-LRGGAGEPGKNGAKG 441
Query: 3765 -PREAGEQGPHGSLG-PKEKGESSTKRKKGQ-----VPGPARSESVGSFGRAPSAP---- 3813
P GE+G G G P KGE G+ +PG A F R P+ P
Sbjct: 442 EPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGF-RGPAGPNGIP 500
Query: 3814 -DKPPRTPRKQATPS--------------------RVLPTKP-KPNSQNKPRPPPSEQRK 3851
+K P R P+ R +P P P S KP PP S+
Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560
Query: 3852 AEPGHTQRKDRLGKAFPQGRP 3872
PG G + P+G+P
Sbjct: 561 GRPGPP------GPSGPRGQP 575
Score = 56.2 bits (134), Expect = 6e-07
Identities = 131/525 (24%), Positives = 165/525 (31%), Gaps = 91/525 (17%)
Query: 3415 GGRQPFAFRGVRRPGAP-GQKARALEGTLPSKRRRVAMPGSAPGPGED-RPPPRGSSPIL 3472
G + P RG P P G +P MPGS GPG D +P P GS
Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ--- 557
Query: 3473 SEGSLPALLHLCSEVAPSTTKGWPETLERPVD------PVTHPIRGCELPSNHQECPP-- 3524
E P PS +G P + P P + RG Q P
Sbjct: 558 GESGRPG------PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKN 611
Query: 3525 ----PSLSPFPAALADGRGDCA---------LDGALERPENEASPGSPGPLLQQALPLGA 3571
P P P +GD L G P PG PGP P GA
Sbjct: 612 GETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP-GA 670
Query: 3572 SLPRPGARGQ-DAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEK----EVSSSH 3626
PG +G A G+R P +G APG RG P + +
Sbjct: 671 ----PGGKGDAGAPGERGPPGLAG---APGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPG 723
Query: 3627 MVSEGGPRGTFH----KGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGE 3682
+ G RG KG +P G D + P+ P G PG+
Sbjct: 724 LQGMPGERGGLGSPGPKGDKGEPGG---PGADGVPGKDGPRGPTGPIGPPGPAGQ--PGD 778
Query: 3683 LARGTENGMKP-ATPKAKPGPSSQGSGSPRP----------GTKTGGGSQPQPAS-GQLQ 3730
G G+ A P+ PG + +G P P G G G + P G+
Sbjct: 779 KGEGGAPGLPGIAGPRGSPGERGE-TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837
Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKS---CTKGPREAGEQGPHGSLG-PKEKGESS 3786
P S P+ P P+ + + P G GP GS G P G S
Sbjct: 838 PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG 897
Query: 3787 TKRKKGQVPGPARSESV-------GSFGRAPSAPDK-------PPRTPRKQA----TPSR 3828
+ K G PGPA + G G A +K PP P T +R
Sbjct: 898 SPGKDGP-PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956
Query: 3829 VLPTKP-KPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
L P P + P P + +PG G PQG P
Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP 1001
Score = 47.8 bits (112), Expect = 2e-04
Identities = 193/831 (23%), Positives = 244/831 (29%), Gaps = 165/831 (19%)
Query: 2321 PTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRT 2380
PT PP G GP P G G + DPG P S + P C S G +
Sbjct: 95 PTRPPN--GQGPQGPKGDPGPPGIPGRNG-DPGIPGQPGSPGSPGPPGICESCPTG-PQN 150
Query: 2381 TAPSSTASDFQSDSPQSHRNASHQTPQGDP--LGPQDLKQR-----SRGYKKKPASTENG 2433
+P + D +S A + P G P GP S GY+ P E G
Sbjct: 151 YSPQYDSYDVKSGVAVGGL-AGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG--EPG 207
Query: 2434 QWKGQAPHGPVTCEVCAASFRSGP-GLSRHKARKHRPH----PGAPAEPSPAALPAQQPL 2488
Q P GP A SGP G R RP PG P PA +P
Sbjct: 208 QAGPSGPPGPP-----GAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF--- 259
Query: 2489 EPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPP 2548
P K HR G + N +G+ T P +G + G+P P
Sbjct: 260 ---------PGMKGHR--GFDGRNGEKGE----TGAPGLKGENGLPGENGAPG-----PM 299
Query: 2549 SPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRG 2608
P P + RP P A R R P G +
Sbjct: 300 GPRG------APGERGRPGL-------PGAAGARGNDGARGSDGQPGPPGPPGTAG---- 342
Query: 2609 KLRGRRLREESILPVSADVISDGRGSRPSPAMASYAAS--PSHCLSVEGGPEADGEQPPR 2666
G + + P + + G R P +A + P + G P GE P
Sbjct: 343 -FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401
Query: 2667 LATLGPGVM-----------EGAAETDQEALCAGETGAQKPPGDR-----MLCPG----- 2705
PG+M GA A G+ GA+ PG R PG
Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461
Query: 2706 ---RMDGAALGEQPTGQKGAS----ARGFWGPRETKAL----GVCKESGSE-PAEDSSRA 2753
DG+ G GA+ A GF GP + G E G+ PA A
Sbjct: 462 GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAA 521
Query: 2754 HSRSEEGVWEENTPPLGP--LGFPETSSSPADSTTSSCLQGLPDNPDTQG-----GVQGP 2806
+GV P GP G P + P G P P +QG G GP
Sbjct: 522 GEPGRDGV------PGGPGMRGMPGSPGGPGS-------DGKPGPPGSQGESGRPGPPGP 568
Query: 2807 EGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCEKPVLPLPTQPS 2866
GP P + PGG + P P PT P
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG--PGPQGPPGKNGETGPQGPPGPTGPG 626
Query: 2867 FEEGGDPTLGPARLP----TDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGFLNSRVPG 2922
++G GP L T + P D G P G R P
Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPP 686
Query: 2923 IDPWAPGLSLWALEPSREAGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMPAPADDSS 2982
APGL A P E G K + P P L +P GL P P D
Sbjct: 687 GLAGAPGLRGGAGPPGPEGG--KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKG 744
Query: 2983 SSLGDVS------------------PEPPSLERERCDGGLPGNTHLLPLRATDFEVLSTK 3024
G + P P ++ +GG PG + R + E
Sbjct: 745 EPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE----- 799
Query: 3025 FEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQSRRTEEAAGAGRAQG 3075
G PGP+ F G G + E A + +G
Sbjct: 800 ------------RGETGPPGPA--GFPGAPGQNGEPGGKGERGAPGEKGEG 836
Score = 46.6 bits (109), Expect = 5e-04
Identities = 95/395 (24%), Positives = 131/395 (33%), Gaps = 74/395 (18%)
Query: 3505 PVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQ 3564
P T P R P N Q P P P + GD + G +P + SPG PG +
Sbjct: 91 PPTAPTR----PPNGQGPQGPKGDPGPPGIPGRNGDPGIPG---QPGSPGSPGPPG--IC 141
Query: 3565 QALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSS 3624
++ P G P+ + D+ ++ + G PG G P
Sbjct: 142 ESCPTG---PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPP---------------- 182
Query: 3625 SHMVSEGGPRGTF-HKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GE 3682
GP GT H GS P G Q + A P P G++ P G
Sbjct: 183 -------GPPGTSGHPGSPGSP-GYQGPPGEPGQAG--------PSGPPGPPGAIGPSGP 226
Query: 3683 LARGTENGMKPATP--KAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAK- 3739
+ E+G +P P + PGP + PG G + + ET K
Sbjct: 227 AGKDGESG-RPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKG 285
Query: 3740 -PSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPA 3798
P + AP + R P E G G G+ G +G + GQ PGP
Sbjct: 286 ENGLPGENGAPGPMGPRG-------APGERGRPGLPGAAG--ARGNDGARGSDGQ-PGPP 335
Query: 3799 RSESVGSFGRAPSAPDK--PPRTPRKQATPSRVLPTKPK--PNSQNKPRPPPSEQRKAEP 3854
F +P A + P +P P + P+ +Q P PP
Sbjct: 336 GPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN------ 389
Query: 3855 GHTQRKDRLGKAFPQGRPLL---RPPKRGTAVHGA 3886
G K +G A G P L R P +GA
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424
Score = 38.1 bits (87), Expect = 0.17
Identities = 32/114 (28%), Positives = 40/114 (35%), Gaps = 12/114 (10%)
Query: 3189 GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRAR 3248
GL G + + EP P+ RG+ AG PG P + + K SPGE P A
Sbjct: 426 GLRGGAGEPGKNGAKGEPGPRGERGE------AGIPGVPGAKGEDGKDGSPGE---PGAN 476
Query: 3249 STPSNPDGAATP---DSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299
P P A + P R P P+ A GEP P
Sbjct: 477 GLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530
Score = 38.1 bits (87), Expect = 0.17
Identities = 26/89 (29%), Positives = 31/89 (34%), Gaps = 9/89 (10%)
Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264
EP K RG G PG G PG + R +P P A P +
Sbjct: 820 EPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA-- 877
Query: 3265 ATALADAGSPGPPRTTPSPSPDPWAGGEP 3293
G PGPP + +P P P G P
Sbjct: 878 ------RGLPGPPGSNGNPGP-PGPSGSP 899
Score = 37.7 bits (86), Expect = 0.23
Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 14/79 (17%)
Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264
EP PK AG+PG P G +G+A +PGER P P GA P
Sbjct: 658 EPGPKGD---------AGAPGAP-GGKGDA--GAPGERGPPGLAGAPGLRGGAGPPGPEG 705
Query: 3265 ATALADAGSPGPPRTTPSP 3283
AG PGPP +P
Sbjct: 706 GKGA--AGPPGPPGAAGTP 722
Score = 37.4 bits (85), Expect = 0.30
Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 11/95 (11%)
Query: 3206 PAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAKKDSPGERAKPRARSTPSNPDGAATP 3260
P P GK AG+ G P G +G+A + PGE+ P A+ P P
Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQ--PGEKGSPGAQGPPGAPGPLGIA 950
Query: 3261 DSASATALADAGSPGPPRTTPSPSPDPWAG--GEP 3293
A L AG PG P SP P G G+P
Sbjct: 951 GITGARGL--AGPPGMPGPRGSPGPQGVKGESGKP 983
Score = 35.8 bits (81), Expect = 0.86
Identities = 58/214 (27%), Positives = 66/214 (30%), Gaps = 32/214 (14%)
Query: 3414 RGGRQPFAFRGVR-RPGAPGQKA-RALEGT--LPSKRRRVAMPGSAPGPGEDRPPPRGSS 3469
RG P +G +PGA G R G LP PG PG D P R S
Sbjct: 968 RGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS 1027
Query: 3470 P----ILSEGSLPALLHLCSEVAPS-----TTKGWPETLERPVDPVTHPIRGCELPSNHQ 3520
P E P P K P P G P+ +
Sbjct: 1028 PGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA-----GAPGPAGSR 1082
Query: 3521 ECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQAL-----------PL 3569
P P RG + G P N +PGSPGP QQ P+
Sbjct: 1083 GAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPV 1142
Query: 3570 GASLPRPGARGQDAEGKRAPLVFSGKRRAPGARG 3603
G S P PG G G P+ G R G RG
Sbjct: 1143 GPSGP-PGKDG--TSGHPGPIGPPGPRGNRGERG 1173
Score = 35.8 bits (81), Expect = 0.86
Identities = 30/97 (30%), Positives = 35/97 (36%), Gaps = 17/97 (17%)
Query: 3209 KHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAA---------- 3258
K HRG A GSPG P GQ+G P P S P DG +
Sbjct: 1106 KGHRGFPGNPGAPGSPG-PAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPG 1164
Query: 3259 ----TPDSASATALADAGSPGPPRTTPSPSPDPWAGG 3291
+ S + G PGPP P +P P GG
Sbjct: 1165 PRGNRGERGSEGSPGHPGQPGPPG--PPGAPGPCCGG 1199
Score = 34.3 bits (77), Expect = 2.5
Identities = 29/84 (34%), Positives = 30/84 (35%), Gaps = 7/84 (8%)
Query: 3213 GKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRA---RSTPSNPDGAATPDSASATALA 3269
G A AGS G P Q K GER R P NP +P A
Sbjct: 1071 GPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGA- 1129
Query: 3270 DAGSPGP--PRTTPSPSPDPWAGG 3291
GSPGP PR PS P G
Sbjct: 1130 -IGSPGPAGPRGPVGPSGPPGKDG 1152
Score = 33.9 bits (76), Expect = 3.3
Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 13/105 (12%)
Query: 3189 GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRAR 3248
G +G+ L P K RG+ + A G+PG P G P ++ R
Sbjct: 1011 GRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHP----GPPGPVGPAGKSGDRGE 1066
Query: 3249 STPSNPDGAATPDSASATALADAGSPGP--PRTTPSPSPDPWAGG 3291
S P+ P GA P G+PGP PR + + A G
Sbjct: 1067 SGPAGPAGAPGP-------AGSRGAPGPQGPRGDKGETGERGAAG 1104
Score = 33.1 bits (74), Expect = 5.6
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 10/103 (9%)
Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGE-AKKDSPGERAKPRARSTPSNP--DGAATPD 3261
E P G AG PG P G +GE PG P AR P P +G P
Sbjct: 835 EGGPPGVAGPPGGSGPAGPPG-PQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893
Query: 3262 SASATALADAGSPGPPRTTPSPSPDPWAG-----GEPLLQATP 3299
S + D G PGP T +P +G G+P + +P
Sbjct: 894 GPSGSPGKD-GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSP 935
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 103 bits (256), Expect = 4e-21
Identities = 306/1259 (24%), Positives = 383/1259 (30%), Gaps = 230/1259 (18%)
Query: 81 QAPSSTPGKRG--SPQTPPGRSPLQAPSRLAGR-AEGSPPQRYILGIASSRTKPTLDETP 137
+ P G RG P PPGR + L G PP LG P L
Sbjct: 111 EGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLG---GNFAPQLSYGY 167
Query: 138 ENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYT 197
+ +P P GP G P PG P + FQ PP
Sbjct: 168 DEKSTGGISVPGPMGPSGP-RGLPGPPGAPGPQG------------FQGPPG-------- 206
Query: 198 SPSATP-RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPE 256
P P A GP RG P PG + +G P P G+P
Sbjct: 207 ----EPGEPGASGPMGPRG-PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261
Query: 257 PIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEE 316
P KG R F L GA PA G + G GA
Sbjct: 262 PGMKGHR------------GFSGLDGAKGDAGPAGPKGEPGSPG--------ENGA---- 297
Query: 317 AVGTGPAYPLPTQPAPSPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAPRPFSDS 371
P Q P LP +G+PG G + +GA PG A P
Sbjct: 298 ----------PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG 347
Query: 372 LHKSLTKILPERPPSAQ--DGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAA 429
+ + P+ P ++ G+ GPP P A +G + G P + A
Sbjct: 348 AVGAKGEAGPQGPRGSEGPQGVRGEPGPPG-------PAGAAGPAGNPGADGQPGAKGAN 400
Query: 430 PGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489
P A P P PGGP + +G+P AP
Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN---SGEP----------GAPGSKGDTGA 447
Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFT 549
P P G++ GP G +G G G+ PGP LP +GG
Sbjct: 448 KGEPGPVGVQ----------GPPGPAGEEGKRGARGE-PGP-TGLPGPPGERGGP----- 490
Query: 550 YNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA--TNTAGSTCSS 607
PGA GVA P+ P G P P SP E+ P A G T S
Sbjct: 491 -GSRGFPGAD----GVAGPK-GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP 544
Query: 608 LSP---MSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSP-----EPPHSLPT 659
SP + P P+ ++ + PGP GP P Q FP P EP +
Sbjct: 545 GSPGPDGKTGPPGPAGQDGR-PGPPGP-----PGARGQAGVMGFPGPKGAAGEPGKAGER 598
Query: 660 HYQPEPAKAFPFPADG-LGAEGAFQCLEETPFPHEGPEVGRGGLQGFP-RAPPPYPTHHF 717
P P DG GA+G E G G QG P A PP
Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658
Query: 718 SLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPP 777
D L G R G + GPPG P
Sbjct: 659 GEQGVPGD---------------------LGAPGPSGARGERGFPGERGVQGPPGPAGPR 697
Query: 778 AAPRVPADAHAGLLSHAKTFLLAGDAQAEG----KDDPLRTGFLPSLAATPFPLPASDL- 832
A P + A GDA A G + P G A P P D
Sbjct: 698 GANGAPGNDGA-----------KGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG 746
Query: 833 DMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT 892
D S + + G+ P + D + PSGP GP+ G
Sbjct: 747 DAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK-GESGPSGPAGPTGARGAPGDRG-- 803
Query: 893 PESKAPPPLPAATPDPQTPRPGDRGCP-ARGRPKTRSLGLAPTEADAPSQGRQQRRGKQL 951
+ PP PA P PG G P A+G P G A + DA G G
Sbjct: 804 ---EPGPPGPAGFAGP----PGADGQPGAKGEP-----GDAGAKGDAGPPGPAGPAGPPG 851
Query: 952 KLFRKDLDSGGAAEGSGSGGGGRASGL--------RPRRNDGLGERPPPRPR-RPRTQAP 1002
+ ++ + GA GS G A+G P + G PP P + + P
Sbjct: 852 PI--GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGP 909
Query: 1003 GSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLR 1062
PA R P P + + P P G G +V +
Sbjct: 910 RGETGPAGR-PGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968
Query: 1063 EYDFASESEEDEQPPPRGP-GFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGD 1121
E F +P +GP G G RG L GP + ++ A G D
Sbjct: 969 ERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA-GPPGESGREGAPGAEGSPGRD 1027
Query: 1122 GAPANPEEPGGSRP-GPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTN 1180
G+P + G + P GP +P A P G A + G DR P P P
Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGA--PGAPGPVGPAGKSG-----DRGETGPAGPAG-PVG 1079
Query: 1181 TETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQP 1240
P A+ P + D E E G G S GL P P
Sbjct: 1080 -------------PVGARGPAGPQGPRGDKGETGE---QGDRGIKGHRGFS-GLQGPPGP 1122
Query: 1241 PPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297
P S + G SG P GS+ PG L G GP G P P PG
Sbjct: 1123 PGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPG 1181
Score = 96.3 bits (238), Expect = 5e-19
Identities = 229/866 (26%), Positives = 272/866 (31%), Gaps = 170/866 (19%)
Query: 6 PRGAPPPT-MTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQ 64
PRG+ P + G+ P A + G P+ P D P KGA A G A A P A+
Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGAAG-PAGNPGADGQPGA---KGANGAPGIAGAPGFPGAR 415
Query: 65 PRQARDGELKPPSLRGQAPS-STPGKRGSP--QTPPGRSPLQAPSRLAGR-----AEGSP 116
G PP +G + PG +G + PG +Q P AG A G P
Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475
Query: 117 PQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDT----PQGPGTGAPLRPGLPRTEAQ 172
+ G R P P + + P + P GP G+P G P
Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGP-KGSPGEAGRPGEAGL 534
Query: 173 PAAEELGFHRCFQEPPSSFTSTNYTSPSATP----RPPAPGPPQSRGTSPLQPGSYPEYQ 228
P A+ L P S T P RP PGPP +RG + + P+
Sbjct: 535 PGAKGL------TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPK-- 586
Query: 229 ASGADSWP-PAAENSFPGANFGVPPA----------EPEPI-PKGSR----PGGSPRGVS 272
GA P A E PG V PA P P P G R P GSP
Sbjct: 587 --GAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP---G 641
Query: 273 FQ-FPFPA-LHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPL---- 326
FQ P PA G + KP V G GP + + + +P E GP P
Sbjct: 642 FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGP---SGARGERGFPGERGVQGPPGPAGPRG 698
Query: 327 ----------------PTQPAPSPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAP 365
P P P QG PG GL G GA S
Sbjct: 699 ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS-- 756
Query: 366 RPFSDSLHKSLTKILPERP-----------PSAQDGLGSTRGPPSSLPQRHFPGQAYRAS 414
P D + I P P PS G RG P + PG A A
Sbjct: 757 -PGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815
Query: 415 --GVDTSPG----PPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQP 468
G D PG P D PP P P P G + A + G
Sbjct: 816 PPGADGQPGAKGEPGDAGAKGDAGPPG-------PAGPAGPPGPIGNVGAPGAKGARGSA 868
Query: 469 SPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP 528
P P +A P P P G P PAG E G +G G AG+
Sbjct: 869 GPPGATGFPGAAGRVGP-------PGPSGNAGPPGPPGPAG-KEGGKGPRGETGPAGRPG 920
Query: 529 GPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQ--VSPHGTPSLPPPRVVGA 586
P + + GSP G P P G PQ G LP R
Sbjct: 921 EVGPPGPPGPAGEKGSP------GADGPAGAP---GTPGPQGIAGQRGVVGLPGQRGERG 971
Query: 587 SPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGS 646
P LP P S P P+ S E PGP+GP PP G+
Sbjct: 972 FPG---LPGP----------SGEPGKQGPSGASGERGP-PGPMGPPGLAGPPGESGREGA 1017
Query: 647 PFPSPEPPHSLPTHYQPEPAKAFPF-PADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGF 705
P P + + + P P GA GA P G RG
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA-----PGPVGPAGKSGDRGETGPA 1072
Query: 706 PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQ 765
A P P + + D T Q DR HR F GL Q
Sbjct: 1073 GPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIK------GHRGFSGL---------Q 1117
Query: 766 RSPGPPGLP--------SPPAAPRVP 783
PGPPG P S PA PR P
Sbjct: 1118 GPPGPPGSPGEQGPSGASGPAGPRGP 1143
Score = 90.5 bits (223), Expect = 3e-17
Identities = 322/1378 (23%), Positives = 400/1378 (29%), Gaps = 312/1378 (22%)
Query: 131 PTLDETPENPQLEAAQLPEVDT----PQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQE 186
P E+P + + + P+ DT P+GP G P R G+P P
Sbjct: 96 PDGSESPTDQETTGVEGPKGDTGPRGPRGPA-GPPGRDGIPGQPGLPG------------ 142
Query: 187 PPSSFTSTNYTSPSATPRPPAPGPPQSRGT-SPLQPGSYPEYQASGADSWPPAAENSFPG 245
P P PP GPP G +P Y E G S PG
Sbjct: 143 ------------PPGPPGPP--GPPGLGGNFAPQLSYGYDEKSTGGI---------SVPG 179
Query: 246 ANFGVPPAEPEPIPKGSRPGGSPRGVSFQFP--FPALHGASTKPFPADVAGHAFTNGPLV 303
+ P+ P +P P G+P FQ P P GAS P G NG
Sbjct: 180 P---MGPSGPRGLPG---PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGD-- 231
Query: 304 FAFHQPQGAWPEEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAA 361
+ P GP P + P + LP +G G S L GA G A
Sbjct: 232 ----DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRG----FSGLDGAKGDAGPA 283
Query: 362 HSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPG 421
P + G G P + R PG+ R +PG
Sbjct: 284 G----------------------PKGEPGSPGENGAPGQMGPRGLPGERGRPG----APG 317
Query: 422 PP-----DTELAAPGPP----PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQ 472
P D A GPP PA P A P GP + G+P P
Sbjct: 318 PAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-- 375
Query: 473 RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--GSQGALGTAGKTPGP 530
P A P P A P G + + P AG P + G G G G G PGP
Sbjct: 376 ----PGPAGAAGPAGNPGADGQP-GAKGANGAPGIAGAPGFPGARGPSGPQGPGGP-PGP 429
Query: 531 REKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSE 590
+ G P G T +P GV P G R P
Sbjct: 430 K--------GNSGEPGAPGSKGDTGAKGEPGPVGVQ----GPPGPAGEEGKRGARGEPGP 477
Query: 591 SPLPSPATNTAGSTCSSLSPMS--SSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPF 648
+ LP P G + P P+ E PGP GP P E G P
Sbjct: 478 TGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS-PGPAGPKGSPGEAGRPGEAGLP- 535
Query: 649 PSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRA 708
AK G +G +T P + GR G G P A
Sbjct: 536 ----------------GAKGLTGSPGSPGPDG------KTGPPGPAGQDGRPGPPGPPGA 573
Query: 709 PPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSP 768
R + + F + G K G + P
Sbjct: 574 -----------------------------RGQAGVMGFPGPKGAAG---EPGKAGERGVP 601
Query: 769 GPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLP 828
GPPG P D AG AG A G+ P + L P
Sbjct: 602 GPPGAVGPAGK-----DGEAGAQGPPGP---AGPAGERGEQGPAGSPGFQGLPGPAGPPG 653
Query: 829 ASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSK 888
+ E D L +G + P + P GP GP +
Sbjct: 654 EAGKPGEQGVPGD-LGAPGPSGARGERGFPGERGV-------QGPPGPAGPRGANGAPGN 705
Query: 889 AGVTPESKAP-PPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRR 947
G ++ AP P P Q PG+RG PK P AD S G+ R
Sbjct: 706 DGAKGDAGAPGAPGSQGAPGLQG-MPGERGAAGLPGPKGDRGDAGPKGADG-SPGKDGVR 763
Query: 948 GKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRAD 1007
G + G A G G SG P P R APG R +
Sbjct: 764 G-----LTGPIGPPGPAGAPGDKGESGPSG-------------PAGPTGARG-APGDRGE 804
Query: 1008 PAPRVPRAAALPEETRSSRRRRLPPRK-DPRKRKARGGAWGKELILKIVQQKNRLREYDF 1066
P P P A P P K +P A+G A
Sbjct: 805 PGPPGPAGFAGPPGADGQ-----PGAKGEPGDAGAKGDAGPP------------------ 841
Query: 1067 ASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDG 1122
+ P P G PG +G RG P P AG G
Sbjct: 842 -GPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG----NAGPPG 896
Query: 1123 APANPEEPGGSRP----GPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVP 1178
P + GG P GP P GP G A +G P AD P+ AP P
Sbjct: 897 PPGPAGKEGGKGPRGETGPAGRPGEVGPPGP--PGPAGEKGSPG-ADGPAGAPGTP---- 949
Query: 1179 TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPE 1238
+ R + P + E P E + P+ +GE G PG + P
Sbjct: 950 -GPQGIAGQRGVVGLPGQRGERGFPGLPGPSG----EPGKQGPSGASGERGP-PGPMGPP 1003
Query: 1239 Q---PPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQ 1295
PP G P GS G+ G G PG AP +
Sbjct: 1004 GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA---------- 1053
Query: 1296 PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL 1355
PG + P P+ PAG P+G PV +GP P +
Sbjct: 1054 PGP-VGPAGKSGDRGETGPA-----------GPAG----PVG-PVGARGPAGPQGPRGD- 1095
Query: 1356 FLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGR 1415
G G + H S PP + G +G+ P PR PPG+A PG+
Sbjct: 1096 -KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQG-PSGASGPAGPRGPPGSAGA-PGK 1152
Query: 1416 AASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSF 1473
LP PP G D+G P PP P PP F
Sbjct: 1153 DG----------LNGLP-GPIGPP--GPRGRTGDAG-PVGPPGPPGPPGPPGPPSAGF 1196
Score = 83.2 bits (204), Expect = 5e-15
Identities = 212/802 (26%), Positives = 259/802 (32%), Gaps = 166/802 (20%)
Query: 27 PGHPSQPPLEDN-TPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRG----Q 81
PG P P L N P + GG + + + PR G PP G Q
Sbjct: 147 PGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPR----GLPGPPGAPGPQGFQ 202
Query: 82 APSSTPGKRGS--------PQTPPGRSPLQAPSRLAGR-----------AEGSPPQRYIL 122
P PG+ G+ P PPG++ + GR A G P +
Sbjct: 203 GPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLP 262
Query: 123 GIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPG-TGAP--LRP-GLPRTEAQPAAEEL 178
G+ R LD + +A P PG GAP + P GLP +P A
Sbjct: 263 GMKGHRGFSGLD----GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318
Query: 179 GFHRCFQEPPSSFTSTNYTSPSATPRPPA-------------------------PGPPQS 213
R + T P+ P P PGPP
Sbjct: 319 AGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378
Query: 214 RGTS--PLQPGSYPEYQASGADSWPP-AAENSFPGANFGVPPAEP--EPIPKGS--RPG- 265
G + PG+ + A GA+ P A FPGA P P P PKG+ PG
Sbjct: 379 AGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGA 438
Query: 266 ----------GSPRGVSFQF-PFPA----LHGASTKPFPADVAG-HAFTNGPLVFAFHQP 309
G P V Q P PA GA +P P + G GP F
Sbjct: 439 PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA 498
Query: 310 QGAWPEEAVGTGPAYPLPTQPAPSPL-----PCYQGQPG--GLNRHSDLSGALSSPGAAH 362
G GP P + +P P P G+PG GL L+G+ SPG
Sbjct: 499 DGV-------AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDG 551
Query: 363 SAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQ---RHFPGQAYRASGVDTS 419
P P+ QDG GPP + Q FPG G
Sbjct: 552 KTGPP----------------GPAGQDGRPGPPGPPGARGQAGVMGFPG----PKGAAGE 591
Query: 420 PGPPDTELAAPGPPPARLPQLWDPTA-APYPTPPGGPL------AATRSMFFNGQPSPGQ 472
PG E PGPP A P D A A P P GP S F G P P
Sbjct: 592 PGKAG-ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAG 650
Query: 473 RLCLPQSAPLPWPQVLP--TARPSPHGMEMLSRLPFPAG--GPEWQGGSQGALGTAGKTP 528
P A P Q +P P P G P G GP G +GA G G
Sbjct: 651 P---PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDG 707
Query: 529 GPREK-LPAVRSSQG-----GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPR 582
+ P SQG G P G+ P G A P+ G+P R
Sbjct: 708 AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDR---GDAGPK-GADGSPGKDGVR 763
Query: 583 VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPP---T 639
+ P P P+ A G + S P + A + + PGP GP+ F PP
Sbjct: 764 GL-TGPIGPPGPAGAPGDKGESGPS-GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG 821
Query: 640 HPQETGSPFPSPEPPHSLPTHYQPEPA--KAFPFPADGLGAEGAFQCLEE------TPFP 691
P G P + + P P PA P P +GA GA T FP
Sbjct: 822 QPGAKGEPGDAGAKGDAGP----PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFP 877
Query: 692 HEGPEVGRGGLQGFPRAPPPYP 713
VG G G A PP P
Sbjct: 878 GAAGRVGPPGPSG--NAGPPGP 897
Score = 79.7 bits (195), Expect = 5e-14
Identities = 196/772 (25%), Positives = 235/772 (30%), Gaps = 156/772 (20%)
Query: 6 PRGAP-PPTMTGDLQPRQVASSPG--HPSQPPLEDNTPATRTTKGAREAGGQAQAMELPE 62
P G P PP G R + G P P E +P KG+ G+ LP
Sbjct: 477 PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPG 536
Query: 63 AQPRQAR------DGELKPPSLRGQ----APSSTPGKRGSPQT---PPGRSPLQAPSRLA 109
A+ DG+ PP GQ P PG RG P + P +
Sbjct: 537 AKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596
Query: 110 GRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPG-TGAPLRPGLPR 168
R PP +G A + + P P A + E PG G P G P
Sbjct: 597 ERGVPGPPGA--VGPAGKDGEAGA-QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653
Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228
+P + + P + + PP P P+ +P G+ +
Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713
Query: 229 ASGADSWPPAAENSFPGANFGVPP---AEPEPIPKGSRPGGSPRGVSF---QFPFPALHG 282
A GA P ++ + PG G+P A P PKG R P+G + L G
Sbjct: 714 APGA----PGSQGA-PGLQ-GMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTG 767
Query: 283 ASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPL---PCYQ 339
P PA G +GP P G P A G P P P+ P
Sbjct: 768 PIGPPGPAGAPGDKGESGP-----SGPAG--PTGARGAPGDRGEPGPPGPAGFAGPPGAD 820
Query: 340 GQPGGLNRHSDLS--GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGP 397
GQPG D G PG A A P I P A+ GS GP
Sbjct: 821 GQPGAKGEPGDAGAKGDAGPPGPAGPAGPP---------GPIGNVGAPGAKGARGSA-GP 870
Query: 398 PSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP-PARLPQLWDPTAAPYPT------ 450
P + FPG A R P P PGPP PA P P
Sbjct: 871 PGATG---FPGAAGRVG-----PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV 922
Query: 451 -PPGGPLAATRSMFFNGQPSPGQRLCLPQSAP-LPWPQVLPTAR-----PSPHGMEMLSR 503
PPG P A G P P AP P PQ + R P G
Sbjct: 923 GPPGPPGPAGEK----GSPGADG----PAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974
Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGP--------------REKLPAVRSSQG--GSPAL 547
LP P+G P QG S GA G G PGP RE P S G GSP
Sbjct: 975 LPGPSGEPGKQGPS-GASGERGP-PGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGA 1032
Query: 548 FTYNGMTDPGAQPLFFGV--AQPQVSPHG-------TPSLPPPRVVGASPSESPL-PSPA 597
G T P P G A V P G T P VG + P P
Sbjct: 1033 KGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGP 1092
Query: 598 TNTAGSTCSS----------LSPMSSSPANPSSEESQ----------------------- 624
G T S + P P S Q
Sbjct: 1093 RGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGK 1152
Query: 625 -----LPGPLGP------SAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEP 665
LPGP+GP + P P G P P P + P+P
Sbjct: 1153 DGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQP 1204
Score = 76.6 bits (187), Expect = 4e-13
Identities = 270/1079 (25%), Positives = 337/1079 (31%), Gaps = 211/1079 (19%)
Query: 1881 GPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLP 1940
GP +DGI G L P P GL G +++ G + S GG+ V
Sbjct: 124 GPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAP--QLSYGYDEKSTGGISVPGPM 181
Query: 1941 AVAGHQLGLE----ADGHWGLLGQAEKTQGQGTANQLQPENGVSP---GGTDNHASVNAS 1993
+G + GL A G G G + G + + P P G D A
Sbjct: 182 GPSGPR-GLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGR 240
Query: 1994 P-KTALTGPT-----EGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHS 2047
P + GP G L KG R L + A+ P P E + A
Sbjct: 241 PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGL-DGAKGDAGPAGPKGEPGSPGENGAPG 299
Query: 2048 RSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDP 2107
+ G G ER PG P A G+ A AA P PT A P G + +
Sbjct: 300 QMGPRGLPGERGR-PGAPGPAGARGNDGATG----AAGPPGPTGPAGPPGFPGAVGAKGE 354
Query: 2108 LTSPSRAQGGLGGQ-LPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPV 2166
P +G G Q + P PPGP A PA P ADG GA+ +
Sbjct: 355 -AGPQGPRGSEGPQGVRGEPG---PPGPAG--AAGPAGNP--GADG-----QPGAKGANG 401
Query: 2167 APPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPE 2226
AP + +P P +G P + P PPG PK ++
Sbjct: 402 AP-GIAGAPGFPGA-------RGPSGP-QGPGG-PPG-------------PKGNS----- 433
Query: 2227 DSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGR-------GLPGPD 2279
PG S GA V G P G+E + G GLPGP
Sbjct: 434 --------GEPGAPGSKGDTGAKGEPGPVGVQGPPG-PAGEEGKRGARGEPGPTGLPGP- 483
Query: 2280 PQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGA-GPDSPACL 2338
P RG P RG G A P P +G+ GP P
Sbjct: 484 PGERGGPGS-------RGFP--------------GADGVAGPKGPAGERGSPGPAGPKGS 522
Query: 2339 EGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSH 2398
GE G P + G P G G T P P G+T P D + P
Sbjct: 523 PGEAG----RPGEAGLP--GAKGLTGSPGSPGPD-----GKTGPPGPAGQDGRPGPPGPP 571
Query: 2399 RNASHQTPQGDPLGPQDL-----KQRSRGYKKKPAST----ENGQWKGQAPHGPVTCEVC 2449
G P GP+ K RG P + ++G+ Q P GP
Sbjct: 572 GARGQAGVMGFP-GPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG---- 626
Query: 2450 AASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHR----- 2504
A R G + + P P P P A P +Q + P + R
Sbjct: 627 PAGERGEQGPAGSPGFQGLPGPAGP--PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE 684
Query: 2505 --VSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPAS 2562
V G P RG P G+K APG+P SQ E + A
Sbjct: 685 RGVQGPPGPAGPRG----ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGE---RGAAG 737
Query: 2563 KPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILP 2622
P P R D PK A+ G+ R T P G + K G P
Sbjct: 738 LPGPKGDRGDA-GPKGADGSPGKDGVRGLT--GPIGPPGPAGAPGDK--GESGPSGPAGP 792
Query: 2623 VSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQ----------PPRLATLGP 2672
A RG P A +A P +G P A GE PP A GP
Sbjct: 793 TGARGAPGDRGEPGPPGPAGFAGPPG----ADGQPGAKGEPGDAGAKGDAGPPGPA--GP 846
Query: 2673 GVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKG-ASARGFWGPR 2731
G G G+ PPG GAA P G G A G GP
Sbjct: 847 AGPPGPIGNVGAPGAKGARGSAGPPGAT-----GFPGAAGRVGPPGPSGNAGPPGPPGPA 901
Query: 2732 ETKALGVCKESGSEPAEDSSRAHSRSEEG-------VWEENTPPL-GPLGFPETSSSPAD 2783
KE G P ++ A E G E+ +P GP G P T P
Sbjct: 902 G-------KEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPG-PQG 953
Query: 2784 STTSSCLQGLPDN-----------PDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFS 2832
+ GLP P + G QGP G + + PP L
Sbjct: 954 IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESG 1013
Query: 2833 QLFPPG--GRLTRKRNPHVYGKRCE-----------KPVLPLPTQPSFEEGGDPTLGPA 2878
+ PG G R +P G R E P P P P+ + G GPA
Sbjct: 1014 REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA 1072
Score = 73.9 bits (180), Expect = 3e-12
Identities = 129/491 (26%), Positives = 161/491 (32%), Gaps = 75/491 (15%)
Query: 3415 GGRQPFAFRGVRRP----GAPGQKARALEGTLPSKRRRVAMPGSA--------PGP-GED 3461
G + P RG P G+PG+ R E LP + PGS PGP G+D
Sbjct: 503 GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD 562
Query: 3462 -RPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWP-ETLER--PVDPVTHPIRGCELPS 3517
RP P G + + P G P + ER P P G + +
Sbjct: 563 GRPGPPGPPGARGQAGVMGF------PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEA 616
Query: 3518 NHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP- 3576
Q P P+ PA +G G P PG G +Q +P P P
Sbjct: 617 GAQGPPGPA---GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPS 673
Query: 3577 GARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGT 3636
GARG+ F G+R G G P + G P
Sbjct: 674 GARGERG--------FPGERGVQGPPGPAGPRG-------------------ANGAPGND 706
Query: 3637 FHKGSATKPA--------GCQSSSKDRSAASTPS-KALKFPVHPRKAVGSLAPG-ELARG 3686
KG A P G Q +R AA P K + P+ A GS PG + RG
Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS--PGKDGVRG 764
Query: 3687 TENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRS 3746
+ P P PG + SG P TG P G+ A P
Sbjct: 765 LTGPIGPPGPAGAPGDKGE-SGPSGPAGPTGARGAPGDR-GEPGPPGPAGFAGPPGADGQ 822
Query: 3747 PAPERLPARAQAKSCTKGPREAGEQGPHGSLG----PKEKGESSTKRKKGQVPGPARSES 3802
P + P A AK P AG GP G +G P KG + G P +
Sbjct: 823 PGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882
Query: 3803 VGSFGRAPSA-PDKPPRTPRKQATPSRVLPTKP--KPNSQNKPRPPPSEQRKAEPGHTQR 3859
VG G + +A P PP K+ T P +P P PP K PG
Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGP 942
Query: 3860 KDRLGKAFPQG 3870
G PQG
Sbjct: 943 AGAPGTPGPQG 953
Score = 70.5 bits (171), Expect = 3e-11
Identities = 236/1034 (22%), Positives = 309/1034 (29%), Gaps = 161/1034 (15%)
Query: 1879 LPGPGVAKSKDGILGL--QELTPAAQSP--PR--VNPSGLEGGTVEGGKVACGPAQGSPG 1932
LPGP A G G + P A P PR P G G E GK +G PG
Sbjct: 189 LPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG 248
Query: 1933 -----GVQVTT-LPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSP----- 1981
G+ T LP + GH+ DG G G A G+ + + P
Sbjct: 249 PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308
Query: 1982 -----------GGTDNHASVNASPKTALTGP-----------TEGAVLLEKCKGSRAAMS 2019
G N + A+ TGP +G + +GS
Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG 368
Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGR--TPERASSPGL-----NKPLLATG 2072
++ E P PP P + A + G++G P A +PG G
Sbjct: 369 VRGE----PGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424
Query: 2073 DSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQ-LPASPSCRDP 2131
P P AP GP+ + P P+ +G G + P P
Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGP-PGPAGEEGKRGARGEPGPTGLPGP 483
Query: 2132 PGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCD---PKEA-LAGC-- 2185
PG + P ADGV E P SP + P EA L G
Sbjct: 484 PGERG----GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539
Query: 2186 LLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTP----KDSTLRIPEDSRKEKLWESPGRAT 2241
L GSP D + PPG P + + P G
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG 599
Query: 2242 SPPLAGAVSPSVAVRATGLSST--PTGDEAQAGRGLPGPDPQSRGAP-PHTNPDRMPRGH 2298
P GAV P+ G P G + G P P +G P P P +
Sbjct: 600 VPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG 659
Query: 2299 SSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPE--DPGTPE 2356
P + G + P E GP P G G + + PG P
Sbjct: 660 EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP- 718
Query: 2357 TGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQT----PQGDPLG 2412
G GA + + GL A +D T P G
Sbjct: 719 -GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA 777
Query: 2413 PQDLKQRSRGYKKKPASTEN--GQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRP- 2469
P D + P G P GP A F PG K P
Sbjct: 778 PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP-------AGFAGPPGADGQPGAKGEPG 830
Query: 2470 ---HPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPP 2526
G P PA PA P P+ P K + +G G V P P
Sbjct: 831 DAGAKGDAGPPGPAG-PAGPP-GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP 888
Query: 2527 AQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRR 2586
+ + G P PP P E K P + P R E+ P G
Sbjct: 889 SGNA-------GPP-----GPPGPAGKE-GGKGPRGETGP-AGRPGEVGPPGPPGPAGE- 933
Query: 2587 WRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAAS 2646
+ P D P+ + G + + G+R + RG R P + +
Sbjct: 934 -KGSPGADGPAGAPGTPGPQ--GIAGQR---------GVVGLPGQRGERGFPGLPGPSGE 981
Query: 2647 PSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGR 2706
P +G A GE+ P PG+ E+ +E G GA+ PG +
Sbjct: 982 PGK----QGPSGASGERGPPGPMGPPGLAGPPGESGRE----GAPGAEGSPGRDGSPGAK 1033
Query: 2707 MDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSE-------PAEDSSRAHSRSE 2758
D G P G GA A G GP +G +SG PA +R
Sbjct: 1034 GDRGETG--PAGPPGAPGAPGAPGP-----VGPAGKSGDRGETGPAGPAGPVGPVGARGP 1086
Query: 2759 EGVWEENTPPLGPLGFPETSSSPADSTTS-----SCLQGLPDNPDTQG-----GVQGPEG 2808
G P GP G + D S LQG P P + G G GP G
Sbjct: 1087 AG-------PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAG 1139
Query: 2809 P--TPDASGSSAKD 2820
P P ++G+ KD
Sbjct: 1140 PRGPPGSAGAPGKD 1153
Score = 67.8 bits (164), Expect = 2e-10
Identities = 108/429 (25%), Positives = 138/429 (32%), Gaps = 52/429 (12%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPP----PRGSSPILSEGSLPALLHL 3483
PG PG A + PG A G+ PP P G + P
Sbjct: 805 PGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGA 864
Query: 3484 CSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCAL 3543
P G+P R P PS + P P P PA G+G
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPG---------PSGNAGPPGP---PGPAGKEGGKGPRGE 912
Query: 3544 DGALERPENEASPGSPGPLLQQALPLGASLP--RPGARG-QDAEGKRAPLVFSGKRRAPG 3600
G RP PG PGP ++ P GA P PG G Q G+R + G+R G
Sbjct: 913 TGPAGRPGEVGPPGPPGPAGEKGSP-GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERG 971
Query: 3601 ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAAST 3660
G P + + S E GP G P G A +
Sbjct: 972 FPGLPGPS--------GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023
Query: 3661 PSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPG-PSSQGSGSPRPGTKTGGG 3719
P + +PG A+G PA P PG P + G P + G
Sbjct: 1024 PGR-------------DGSPG--AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGE 1068
Query: 3720 SQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPRE-AGEQGPHGSLG 3778
+ P +G + A PA P + P ++ Q KG R +G QGP G G
Sbjct: 1069 TGPAGPAGPVGPVGARGPAGP----QGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124
Query: 3779 -PKEKGESSTKRKKGQVPGPARSESVGSFG-RAPSAPDKPPRTPRKQATPSRVLPTKPKP 3836
P E+G S G P + + G G P PP + V P P P
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGP-P 1183
Query: 3837 NSQNKPRPP 3845
P PP
Sbjct: 1184 GPPGPPGPP 1192
Score = 67.4 bits (163), Expect = 3e-10
Identities = 169/642 (26%), Positives = 207/642 (32%), Gaps = 104/642 (16%)
Query: 3 GER----PRGAPP-PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQA 57
GER P G+P + G P A PG P + P +G R G+
Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG-DLGAPGPSGARGERGFPGERGV 687
Query: 58 MELPEAQPRQARDGELKPPSLRGQAPS-STPGKRGSP--QTPPG-RSPLQAPSRLAGR-- 111
P + +G +G A + PG +G+P Q PG R P R
Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD 747
Query: 112 -----AEGSPPQRYILGIASSRTKPTL-----DETPENPQLEAAQLPEVDTPQGPGTGAP 161
A+GSP + + G+ P D+ P A P G P
Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGP 807
Query: 162 LRP----GLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTS 217
P G P + QP A+ EP + + P P PA GPP
Sbjct: 808 PGPAGFAGPPGADGQPGAKG--------EPGDAGAKGDAGPPG--PAGPA-GPP-----G 851
Query: 218 PLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPE--------PIPKGSRPGGSPR 269
P+ P + + + PP A FPGA V P P P P G G PR
Sbjct: 852 PIGNVGAPGAKGARGSAGPPGA-TGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPR 910
Query: 270 GVSFQFPFPALHGASTKPFPADVAGHAFTNGPL-VFAFHQPQGAWPEEAV----GTGPAY 324
G + P G P PA G +GP PQG + V G
Sbjct: 911 GETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGER 970
Query: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384
P P PS P QG P G + G + PG A P +S E
Sbjct: 971 GFPGLPGPSGEPGKQG-PSGASGERGPPGPMGPPGLA----GPPGESGR--------EGA 1017
Query: 385 PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP-PPARLPQLWDP 443
P A+ G G P + R G A G +PG P APGP PA
Sbjct: 1018 PGAEGSPGRD-GSPGAKGDRGETGPA----GPPGAPGAP----GAPGPVGPAGKSGDRGE 1068
Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503
T P P GP+ A G P P+ + G L
Sbjct: 1069 TGPAGPAGPVGPVGA------RGPAGPQG----PRGDKGETGEQGDRGIKGHRGFSGLQG 1118
Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQP--- 560
P P G P QG S GA G AG P G+P NG+ P P
Sbjct: 1119 PPGPPGSPGEQGPS-GASGPAGPRGPP---------GSAGAPGKDGLNGLPGPIGPPGPR 1168
Query: 561 LFFGVAQPQVSPHGTPSLP-PPRVVGASPSESPLPSPATNTA 601
G A P V P G P P PP A S LP P A
Sbjct: 1169 GRTGDAGP-VGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKA 1209
Score = 67.0 bits (162), Expect = 3e-10
Identities = 235/978 (24%), Positives = 311/978 (31%), Gaps = 195/978 (19%)
Query: 1656 PFSPRGANFHFQPVQKAGASK--TGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAK- 1712
P P G +F P G + TG G P LP P PGPQ G +
Sbjct: 149 PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP 208
Query: 1713 ----CSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPE-----PGTADQP----H 1759
S P + + E P E RG P+ PGTA P H
Sbjct: 209 GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE-RGPPGPQGARGLPGTAGLPGMKGH 267
Query: 1760 RG--------------APAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQG 1805
RG P E GSP + AP G P + P P+ A
Sbjct: 268 RGFSGLDGAKGDAGPAGPKGEP-GSPGENGAP--GQMGPRGLPGERGRPGAPGPAGARGN 324
Query: 1806 HSAGRAGGHLHPT--AGRPGFEG-----NEFAPAGASSLTAPRGREAWLVPVPSPACVSN 1858
A A G PT AG PGF G E P G P+G P P PA +
Sbjct: 325 DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAG 383
Query: 1859 THPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRV----NPSGLEG 1914
PA +P PG A GI G P A+ P P G +G
Sbjct: 384 ---------PAGNPGAD--GQPGAKGANGAPGIAGAPGF-PGARGPSGPQGPGGPPGPKG 431
Query: 1915 GTVE----GGKVACGPAQGSPGGVQVTTLPAVAGHQ--LGLEAD-GHWGLLGQAEKTQGQ 1967
+ E G K G A+G PG V V P AG + G + G GL G + G
Sbjct: 432 NSGEPGAPGSKGDTG-AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP 490
Query: 1968 GTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPT 2027
G+ + P G A SP A + G E + A + + +
Sbjct: 491 GSRGFPGADGVAGPKGP---AGERGSPGPAGPKGSPG----EAGRPGEAGLPGAKGLTGS 543
Query: 2028 PSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAP 2087
P P P+ + T +G +GR PG P A G + P
Sbjct: 544 PGSPGPDGK------TGPPGPAGQDGR-------PGPPGPPGARGQAGVMGF-------P 583
Query: 2088 SPTSAAHMPCSLGP--LPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWA 2145
P AA P G +P P+ G G Q P P+ +Q A SP +
Sbjct: 584 GPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643
Query: 2146 PLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCL-------LQGE-GSPLEDP 2197
L P PP P ++ + G L +GE G P E
Sbjct: 644 GL---------------PGPAGPPGEAGKP--GEQGVPGDLGAPGPSGARGERGFPGERG 686
Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257
PPG P+ + +PG + AGA + A
Sbjct: 687 VQGPPGPAG----------PRGAN-------------GAPGNDGAKGDAGAPGAPGSQGA 723
Query: 2258 TGLSSTPTGDEAQAGRGLPGP-----DPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHR 2312
GL P G+ A GLPGP D +GA D + P A
Sbjct: 724 PGLQGMP-GERGAA--GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD 780
Query: 2313 EGQAVTAVPTEPPTLQGA-------GPDSPACLEGEMGTSSKEPEDPGTP-ETGRSGATK 2364
+G++ + P P +GA GP PA G G +P G P + G G
Sbjct: 781 KGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG-QPGAKGEPGDAGAKGDAG 839
Query: 2365 MPRVTCPSTGLG-LGRTTAP------SSTASDFQSDSPQSHRNASHQTPQGD--PLGPQD 2415
P P+ G +G AP S + P + P G+ P GP
Sbjct: 840 PPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG 899
Query: 2416 LKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHP-GAP 2474
+ G + + G+ P GP PG + K P GAP
Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGP-------------PGPAGEKGSPGADGPAGAP 946
Query: 2475 AEPSPAALPAQQPLEPL----AQKCQPPRKKSHRVSGKERPNHSRGD--------PSHVT 2522
P P + Q+ + L ++ P GK+ P+ + G+ P +
Sbjct: 947 GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006
Query: 2523 QPPPAQGSKEVLRAPGSP 2540
PP G + A GSP
Sbjct: 1007 GPPGESGREGAPGAEGSP 1024
Score = 67.0 bits (162), Expect = 3e-10
Identities = 121/477 (25%), Positives = 158/477 (33%), Gaps = 109/477 (22%)
Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488
GAPGQ LP +R R PG A G D P
Sbjct: 296 GAPGQMGPR---GLPGERGRPGAPGPAGARGNDGATGAAGPP--------------GPTG 338
Query: 3489 PSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALE 3548
P+ G+P + + RG E P + P P P PA A G+ DG
Sbjct: 339 PAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP---PGPAGAAGPAGNPGADG--- 392
Query: 3549 RPENEASPGSPGPLLQQALPLGASLPRPGARG----QDAEGKRAPLVFSGKRRAPGARGR 3604
+P + + G+PG + + PGARG Q G P SG+ APG++G
Sbjct: 393 QPGAKGANGAPG--------IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKG- 443
Query: 3605 CAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS-K 3663
+ E GP G P G R A P
Sbjct: 444 -------------------DTGAKGEPGPVG------VQGPPGPAGEEGKRGARGEPGPT 478
Query: 3664 ALKFPVHPRKAVGS--------LAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTK 3715
L P R GS +A + G PA PK PG + + + PG K
Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK 538
Query: 3716 --TGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLP-ARAQA--------KSCTKG 3764
TG P P + T P P+ P P P AR QA K
Sbjct: 539 GLTGSPGSPGP-------DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE 591
Query: 3765 PREAGEQ---GPHGSLGPKEK-GESSTKRKKGQV-PGPARSES--VGSFG----RAPSAP 3813
P +AGE+ GP G++GP K GE+ + G P R E GS G P+ P
Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651
Query: 3814 DKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQG 3870
P +Q P + P P + + PG + G A P+G
Sbjct: 652 PGEAGKPGEQGVPGDL----------GAPGPSGARGERGFPGERGVQGPPGPAGPRG 698
Score = 62.8 bits (151), Expect = 7e-09
Identities = 106/437 (24%), Positives = 143/437 (32%), Gaps = 71/437 (16%)
Query: 3483 LCSEVAPSTTKGWP--ETLERPVDPVTHPIRGCELPSNHQEC--PPPSLSPFPAALADGR 3538
LC +V TK P E E PV G E P++ + P P
Sbjct: 69 LCDDVICDETKNCPGAEVPEGECCPVCPD--GSESPTDQETTGVEGPKGDTGPRGPRGPA 126
Query: 3539 GDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRA-----PLVFS 3593
G DG +P PG PGP L G + + G D + P+ S
Sbjct: 127 GPPGRDGIPGQPGLPGPPGPPGPPGPPGL--GGNFAPQLSYGYDEKSTGGISVPGPMGPS 184
Query: 3594 GKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSK 3653
G R PG G P FQ E S GPRG P G +
Sbjct: 185 GPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPM-----GPRG---------PPGPPGKNG 230
Query: 3654 DRSAASTPSK-ALKFPVHPRKAVG----SLAPGELAR-------GTENGMKPATPKAKPG 3701
D A P + + P P+ A G + PG G + PA PK +PG
Sbjct: 231 DDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPG 290
Query: 3702 PSSQGSGSPRPGTKTGGGSQPQPAS----GQLQSETATTPAKPSFPSRSPAPERLPARAQ 3757
+ + G + G + +P + G ++ AT A P P+ P P
Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVG 350
Query: 3758 AKSCTKGPREAGEQGPHGSLGPK----EKGESSTKRKKGQVPGPARSESVGSFG------ 3807
AK EAG QGP GS GP+ E G G P G+ G
Sbjct: 351 AKG------EAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404
Query: 3808 ----------RAPSAPDKP--PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855
R PS P P P P+ + +K ++ +P P + G
Sbjct: 405 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG 464
Query: 3856 HTQRKDRLGKAFPQGRP 3872
++ G+ P G P
Sbjct: 465 EEGKRGARGEPGPTGLP 481
Score = 59.7 bits (143), Expect = 6e-08
Identities = 286/1248 (22%), Positives = 366/1248 (29%), Gaps = 255/1248 (20%)
Query: 1232 PGLLIPE-----------QPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGT 1280
PG +PE + P + TG P G P G + PG + G PG
Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141
Query: 1281 QAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPV 1340
P PP G F P+ S + S+ G G P+G
Sbjct: 142 GPPGPPGPPGPPG-LGGNF-----------APQLSYGYDEKSTGGISVPG----PMGPSG 185
Query: 1341 AKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGE-------- 1392
+ P P +P + F GP G E P PP DGE
Sbjct: 186 PRGLPGPPGAPGPQGFQGPPGEPG---EPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242
Query: 1393 DAGSLEPQLPRSPPGTA-------------------ETEPGRAASPPTLESSSLFP---- 1429
+ G PQ R PGTA + P P + P
Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG 302
Query: 1430 --DLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPP-YPSFLLLE-EVSPMLPS 1485
LP +R P G A + G A A PP T P+ PP +P + + E P P
Sbjct: 303 PRGLPGERGRPGAPGPAGARGNDGATGA-AGPPGPTGPAGPPGFPGAVGAKGEAGPQGPR 361
Query: 1486 HFPDLSGGKVLSKTCPPERTVV------PGA-----------------APSLPG------ 1516
G V + PP PGA AP PG
Sbjct: 362 GSEGPQG--VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419
Query: 1517 -KGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVG-RVELG-T 1573
+G G + E K T + + +G P E G R E G T
Sbjct: 420 PQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE-PGPVGVQGPPGPAGEEGKRGARGEPGPT 478
Query: 1574 GTE-PPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPC 1632
G PP +R P F AD + A G+ +G PG
Sbjct: 479 GLPGPPGERGG-----PGSRGFPGADGVAGPKGPAGERGSPGPAGP----KGSPG----- 524
Query: 1633 PASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDV 1692
+ PG A LP A+ ++G+P SP G + P AG D RP
Sbjct: 525 -EAGRPGEAG-LPGAKG--LTGSPGSP-GPDGKTGPPGPAGQ----------DGRP---- 565
Query: 1693 CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEP 1752
P PG + AG + P P ++ + G P
Sbjct: 566 ---GPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622
Query: 1753 GTADQP-HRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWP--------FGASPSHAA 1803
G A RG P GSP P G PP +A P GA A
Sbjct: 623 GPAGPAGERGEQGPA--GSPGFQGLP-----GPAGPPGEAGKPGEQGVPGDLGAPGPSGA 675
Query: 1804 QGHSA--GRAGGHLHPTAGRP----GFEGNEFAPAGASSLTAPRGREA-WLVPVPSPACV 1856
+G G G P P G GN+ A A + AP + A L +P
Sbjct: 676 RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA 735
Query: 1857 SNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGT 1916
+ + + A GP A G G++ LT P G +G +
Sbjct: 736 AGLPGPKGDRGDA-----------GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGES 784
Query: 1917 VEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPE 1976
G A+G+PG P AG ADG G G+ +G A P
Sbjct: 785 GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844
Query: 1977 NGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNR 2035
PG N + A GP GA G A P P PP P
Sbjct: 845 GPAGPPGPIGNVGAPGAKGARGSAGP-PGATGFPGAAGRVGPPGPSGNAGP-PGPPGP-- 900
Query: 2036 ESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHM 2095
+G EG R + +P P G+ +P A
Sbjct: 901 -------------AGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKG--SPGADGPAGA 945
Query: 2096 PCSLGPLPREDPLTSPSRAQGGLGGQ-----LPASPSCRDPPGPQQLLACSPAWAPLEEA 2150
P + GP + R GL GQ P P PG Q
Sbjct: 946 PGTPGPQG-----IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ--------------- 985
Query: 2151 DGVQATTDTGAEDSPVAPPSLTTSPCDP-KEALAGCLLQGEGSPLEDPSSWPPGSVSAVT 2209
G + P+ PP L P + +E G EGSP D S G
Sbjct: 986 -GPSGASGERGPPGPMGPPGLAGPPGESGREGAPG----AEGSPGRDGSPGAKGDRGETG 1040
Query: 2210 CTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPL--AGAVSPSVAVRATGLSSTPTGD 2267
P P +S R + P AG V P V R P GD
Sbjct: 1041 PAGPPGAPGAPGAPGPVG----PAGKSGDRGETGPAGPAGPVGP-VGARGPAGPQGPRGD 1095
Query: 2268 EAQAGR-------------GLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREG 2314
+ + G GL GP P G+P P P +A ++G
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGP-PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDG 1154
Query: 2315 QAVTAVPTEPPTLQG----AGPDSPACLEGEMGTSSKEPEDPGTPETG 2358
P PP +G AGP P G P PG P G
Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGPPG-------PPGPPGPPSAG 1195
Score = 58.2 bits (139), Expect = 2e-07
Identities = 138/542 (25%), Positives = 171/542 (31%), Gaps = 115/542 (21%)
Query: 3422 FRGVRRP-------GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSE 3474
F G R P G PG K + E P + G PGP + PP P E
Sbjct: 411 FPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE-PGPVGVQGPP---GPAGEE 466
Query: 3475 GSLPALLHLCSEVAPSTTKGWPETLERPVD---PVTHPIRGCELPSNHQECPPPSLSPFP 3531
G A E P+ G P P P + G + P+ + P P+
Sbjct: 467 GKRGAR----GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522
Query: 3532 AALADGRGDCALDGALERPENEASPGS------PGPLLQQALPLGASLPRPGARGQDA-- 3583
A G+ L GA + SPG PGP Q P G P PGARGQ
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRP-GPPGP-PGARGQAGVM 580
Query: 3584 -----EGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFH 3638
+G +G+R PG G P K+ E + GP G
Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGP--------AGKDGEAGAQGPPGPAGPAG--- 629
Query: 3639 KGSATKPAGCQSSSKDRSAASTPSKALKFPVH----------PRKAVGSLA-PGELARGT 3687
+ PAG A P +A K P A G PGE RG
Sbjct: 630 ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE--RGV 687
Query: 3688 ENGMKPATPKAKPG-PSSQGS----GSP-RPGTKTGGGSQPQP----ASGQLQSETATTP 3737
+ PA P+ G P + G+ G+P PG++ G Q P A+G +
Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD 747
Query: 3738 AKPSFPSRSPAPER---LPARAQAKSCTKGPREAGEQGPHGSLGPK-------------- 3780
A P SP + L P + GE GP G GP
Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGP 807
Query: 3781 -----------------EKGESSTKRKKGQV--PGPARSES----VGSFGRAPSAPDK-- 3815
KGE KG PGPA +G+ G AP A
Sbjct: 808 PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVG-APGAKGARG 866
Query: 3816 ---PPRTPRKQATPSRVLPTKPKPNS--QNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQG 3870
PP RV P P N+ P P E K G T R G+ P G
Sbjct: 867 SAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG 926
Query: 3871 RP 3872
P
Sbjct: 927 PP 928
Score = 47.8 bits (112), Expect = 2e-04
Identities = 176/707 (24%), Positives = 212/707 (29%), Gaps = 157/707 (22%)
Query: 2632 RGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGET 2691
+G+R P A H G DG + GP +G + E G+
Sbjct: 250 QGARGLPGTAGLPGMKGH----RGFSGLDGAK----GDAGPAGPKGEPGSPGENGAPGQM 301
Query: 2692 GAQKPPGDRML--CPGRM-----DGAALGEQPTGQKG-ASARGFWGPRETKALGVCKESG 2743
G + PG+R PG DGA P G G A GF G A+G E+G
Sbjct: 302 GPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG-----AVGAKGEAG 356
Query: 2744 SEPAEDSSRAHSRSEEGVWEENTPP-----LGPLGFPETSSSPADSTTSSC--LQGLPDN 2796
+ S +GV E PP GP G P P + + G P
Sbjct: 357 PQGPRGSE-----GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411
Query: 2797 PDTQG--GVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPG--GRLTRKRNPHVYGK 2852
P +G G QGP GP S P D + + P G G G
Sbjct: 412 PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471
Query: 2853 RCEKPVLPLPTQPSFEEGG---------DPTLGPARLPTDLSDSSSLCLCHEDPWEDEDP 2903
R E LP P E GG D GP + P S P E P
Sbjct: 472 RGEPGPTGLPGPPG-ERGGPGSRGFPGADGVAGP-KGPAGERGSPGPAGPKGSPGEAGRP 529
Query: 2904 --AGLPESFLLDGFLNSRVPGIDPWAPGLSLWALEPSR--------EAGAEKLPSHCPED 2953
AGLP + L G S P PG + P +AG P
Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA 589
Query: 2954 DRPEAIPELHMVPAAWRGLEMPAPADDSSSSLGDVSPEPPSLER-ERCDGGLPGNTHLLP 3012
P E VP G PA D + + G P P+ ER E+ G PG
Sbjct: 590 GEPGKAGE-RGVPGP-PGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG------ 641
Query: 3013 LRATDFEVLSTKFEMQDLCFLGPFEDPVGLPGPSFLDFEGTASSQGPQSRRTEEA-AGAG 3071
F+ L GP P P G + GP R E G
Sbjct: 642 -----FQGLP-----------GPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGER 685
Query: 3072 RAQGRGRPAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPTCYMCVERRFGSREL- 3130
QG PA R A+ + G A P P GS+
Sbjct: 686 GVQGPPGPAGPRGAN----------GAPGNDGAKGDAGAPGAP-----------GSQGAP 724
Query: 3131 -LRGHLQERHAQSKAGPWACGMCLKEVADVWMYNEHLREHAVRFARRGQARRSLGDLPGG 3189
L+G ER A GP RG A D G
Sbjct: 725 GLQGMPGERGAAGLPGPKG--------------------------DRGDAGPKGAD---G 755
Query: 3190 LEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARS 3249
G V L I P P G + +G P P G G +PG+R +P
Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSG-PAGPTGARG-----APGDRGEPG--- 806
Query: 3250 TPSNPDGAATPDSAS-----------ATALADAGSPGPPRTTPSPSP 3285
P P G A P A A A DAG PGP P P
Sbjct: 807 -PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP 852
Score = 41.6 bits (96), Expect = 0.016
Identities = 39/119 (32%), Positives = 46/119 (38%), Gaps = 25/119 (21%)
Query: 3189 GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPG--------DPWGQEGEAKKDSPG 3240
G+ G A L P PK RG A GSPG P G G A +PG
Sbjct: 728 GMPGERGAAGL------PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPA--GAPG 779
Query: 3241 ERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299
++ + S P G A P A A D G PGPP P P A G+P + P
Sbjct: 780 DKGE-------SGPSGPAGPTGARG-APGDRGEPGPPGPAGFAGP-PGADGQPGAKGEP 829
Score = 36.2 bits (82), Expect = 0.66
Identities = 26/105 (24%), Positives = 34/105 (32%)
Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPR 3246
P G G + + E P+ RG G PG P +PG +P
Sbjct: 336 PTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPG 395
Query: 3247 ARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGG 3291
A+ P A P A + PG P S +P A G
Sbjct: 396 AKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG 440
Score = 36.2 bits (82), Expect = 0.66
Identities = 33/110 (30%), Positives = 39/110 (35%), Gaps = 12/110 (10%)
Query: 3209 KHHRGKRSAGKAAGSPGDPWGQEGEAKKDSP-GERAKPRARSTPS--------NPDGAAT 3259
K HRG G PG P G++G + P G R P + P P G
Sbjct: 1108 KGHRGFSGLQGPPGPPGSP-GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG 1166
Query: 3260 PDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATPVHEACKDPSR 3309
P + A G PGPP P P P AG + P E D R
Sbjct: 1167 PRGRTGDA-GPVGPPGPP-GPPGPPGPPSAGFDFSFLPQPPQEKAHDGGR 1214
Score = 35.4 bits (80), Expect = 1.1
Identities = 38/150 (25%), Positives = 54/150 (36%), Gaps = 11/150 (7%)
Query: 3177 GQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKK 3236
G A + G P G G + + P P +G A AG+PG P G +G A +
Sbjct: 899 GPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP-GPQGIAGQ 957
Query: 3237 DS----PGERAKPRARSTPSNPDGAATPDSASAT-ALADAGSPGP--PRTTPSPSPDPWA 3289
PG+R + R P P + P + A + G PGP P P +
Sbjct: 958 RGVVGLPGQRGE---RGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGR 1014
Query: 3290 GGEPLLQATPVHEACKDPSRDCHHCGKRFP 3319
G P + +P + D G P
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGP 1044
Score = 35.0 bits (79), Expect = 1.5
Identities = 39/112 (34%), Positives = 44/112 (39%), Gaps = 30/112 (26%)
Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRG-------KRSAGKAA--GSPGDPWGQEGE---- 3233
P G G A L P K HRG K AG A G PG P G+ G
Sbjct: 249 PQGARGLPGTAGL------PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSP-GENGAPGQM 301
Query: 3234 AKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285
+ PGER +P A P GA D A+ AG PGP T P+ P
Sbjct: 302 GPRGLPGERGRPGA----PGPAGARGNDGATGA----AGPPGP--TGPAGPP 343
Score = 34.7 bits (78), Expect = 1.9
Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 8/83 (9%)
Query: 3203 ITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDS 3262
I+ P P G R G+PG P G +G PGE +P A S P P G P
Sbjct: 175 ISVPGPMGPSGPRGLPGPPGAPG-PQGFQG-----PPGEPGEPGA-SGPMGPRGPPGPPG 227
Query: 3263 ASATALADAGSPGPPRTTPSPSP 3285
+ +AG PG P P P
Sbjct: 228 KNGDD-GEAGKPGRPGERGPPGP 249
Score = 33.1 bits (74), Expect = 5.6
Identities = 33/118 (27%), Positives = 37/118 (31%), Gaps = 17/118 (14%)
Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDP-----WGQEGEAKKDS--- 3238
P G GS A S E G A GSPG P G G A +D
Sbjct: 507 PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPG 566
Query: 3239 ----PGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGE 3292
PG R + P A P A + G PGPP D AG +
Sbjct: 567 PPGPPGARGQAGVMGFPGPKGAAGEPGKA-----GERGVPGPPGAVGPAGKDGEAGAQ 619
Score = 32.7 bits (73), Expect = 7.3
Identities = 35/123 (28%), Positives = 41/123 (33%), Gaps = 17/123 (13%)
Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGS------PGDPWGQEGEAKKDSPG 3240
P G +GS + P P+ G+R G PG P G GE K P
Sbjct: 930 PAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP-GPSGEPGKQGPS 988
Query: 3241 ERAKPRARSTPSNPDGAATPDSASATALADA--------GSPGPP--RTTPSPSPDPWAG 3290
+ R P P G A P S A GSPG R P+ P A
Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048
Query: 3291 GEP 3293
G P
Sbjct: 1049 GAP 1051
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 103 bits (256), Expect = 4e-21
Identities = 311/1313 (23%), Positives = 406/1313 (30%), Gaps = 268/1313 (20%)
Query: 28 GHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQ------ 81
G P P L P T T G + G LP + + G PP L G
Sbjct: 337 GPPGPPGLVIPRPGTGITIGEK---GNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393
Query: 82 ---APSSTPGKRGSP--QTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDE- 135
P PG+RG + PPG S + P L G+ G+P G A P+ DE
Sbjct: 394 GPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQP-GAPGLPGPPGPAGPHIPPS-DEI 450
Query: 136 ----------TPENPQLEAAQLPEVDTPQ------GPG-TGAPLRPGLPRTEAQPAAEEL 178
+P + L+ Q + D G G +G P +PGLP P + L
Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS--L 508
Query: 179 GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPA 238
GF E + + P P APG P S+G +PG + D
Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG----EPGDILTFPGMKGDK---- 560
Query: 239 AENSFPGANFGVP--PAEP--EPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAG 294
E PGA G+P P P + +P P G P G++F+ G P + G
Sbjct: 561 GELGSPGAP-GLPGLPGTPGQDGLPGLPGPKGEPGGITFK-------GERGPPGNPGLPG 612
Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGA 354
GP+ P G P VG + P +P +G PG G
Sbjct: 613 LPGNIGPM-----GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667
Query: 355 LSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRAS 414
+PG P L P +P G+ ++G P +P PG
Sbjct: 668 PGNPGRDGDVGLPGDPGL--------PGQP--GLPGIPGSKGEPG-IPGIGLPGPP-GPK 715
Query: 415 GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPS-PGQR 473
G PGPP APG P R+ P +P P G P A G P PG +
Sbjct: 716 GFPGIPGPP----GAPGTP-GRIGLEGPPGPPGFPGPKGEPGFALPGP--PGPPGLPGFK 768
Query: 474 LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAG--GPEWQGGSQGALGTAG----KT 527
L +P P P G L LP P G GP Q G G G G
Sbjct: 769 GALGPKGDRGFP-----GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823
Query: 528 PGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVG-- 585
PGP G+ P QP G+ + P G P L P G
Sbjct: 824 PGPP--------------------GIPGPIGQPGLHGIPGEKGDP-GPPGLDVPGPPGER 862
Query: 586 ASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETG 645
SP P P + P S + S PG G PP P G
Sbjct: 863 GSPGIPGAPGP-----------IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911
Query: 646 SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGF 705
P S P Q +P P P G++G L P P + +G G +G
Sbjct: 912 IPGRSGVPGLKGDDGLQGQPG--LPGPTGEKGSKGE-PGLPGPPGPMDPNLLGSKGEKGE 968
Query: 706 PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQ 765
P P + + + GL + G
Sbjct: 969 PGLP--------------------------------GIPGVSGPKGYQGLPGDPGQPGLS 996
Query: 766 RSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGD---AQAEGKDDPLRTGFLPSLAA 822
PG PG P P P +P GL+ GD +G + P +P
Sbjct: 997 GQPGLPGPPGPKGNPGLP--GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054
Query: 823 TPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSG 882
+P LP D + D + S+ L G + + P + G +G S G
Sbjct: 1055 SP-GLPGQKGD-KGDPGISSIGLPGLPGPKGEPGLPGYPGN----------PGIKG-SVG 1101
Query: 883 HPLKSKAGVTPESKAPPPLPA--ATPDPQTPR-----PGDRGCPARGRPKTRSLGLAPTE 935
P TP +K P LP TP P P+ PG+ G P G P G P +
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP--GEPGPVGGGGHPGQ 1159
Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPR 995
P G + + G+ G G+ G GL ++ DG P P
Sbjct: 1160 PGPP--GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG 1217
Query: 996 RPRTQA-------------PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042
P + PG P P + P R LP + P
Sbjct: 1218 LPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGN 1277
Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGP 1102
GG G E+ P PG G +G QGP
Sbjct: 1278 GGIKG-----------------------EKGNPGQPGLPGLPGLKG----------DQGP 1304
Query: 1103 REDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPK 1162
+ R G G P P PG GP P + GP EG P
Sbjct: 1305 PGLQGNPGRPGLNGMKGDPGLPGVPGFPG--MKGPSGVPGSAGP-----------EGEPG 1351
Query: 1163 CADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPA 1222
+ P P +P + S + P +P P + PP
Sbjct: 1352 L-----IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1406
Query: 1223 ----------ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSS 1265
AG PGL P Q P +R G P P G P G+S
Sbjct: 1407 DPGRNGLPGFDGAGGRKGDPGL--PGQ-PGTRGLDGPPGPDGLQGPPGPPGTS 1456
Score = 85.5 bits (210), Expect = 9e-16
Identities = 193/783 (24%), Positives = 245/783 (31%), Gaps = 176/783 (22%)
Query: 16 GDLQPRQVASSPGHPSQP--PLEDNTPATRTT----KGAREAGGQAQAMELPEAQPRQAR 69
G P+ + PG P P P P T KG + G A LP +
Sbjct: 521 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQ 580
Query: 70 DGELKPPSLRGQAPSST-PGKRGSPQTP--PGRSPLQAPSRLAGRAEGSPP-QRYILGIA 125
DG P +G+ T G+RG P P PG P G P ++ I G+A
Sbjct: 581 DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA 640
Query: 126 SSRTKPTLDETPENPQLEAAQLPEVDTPQGPGT-------------GAPLRPGLPRTEAQ 172
+ +P + +P Q + P PG G P PG+P ++ +
Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700
Query: 173 PAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPA-------PGPPQSRGTSPLQPGSYP 225
P +G PP P P P PGPP G P P
Sbjct: 701 PGIPGIGL----PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG-----PKGEP 751
Query: 226 EYQASGADSWP----------PAAENSFPGANFGVPPAEPE-------PIPKGS-RPGGS 267
+ G P P + FPG PP P P PKG P G
Sbjct: 752 GFALPGPPGPPGLPGFKGALGPKGDRGFPG-----PPGPPGRTGLDGLPGPKGDVGPNGQ 806
Query: 268 PR--------GVSFQFPF--PALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEA 317
P G+ Q P P + G +P + G GP P G
Sbjct: 807 PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG 866
Query: 318 VGTGPAYPLPTQPAPSP-LPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSL 376
+ P P P P SP LP G G ++ G + PG P P +
Sbjct: 867 I---PGAPGPIGPPGSPGLPGKAGASGFPGTKGEM-GMMGPPGP----PGPLGIPGRSGV 918
Query: 377 TKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAA------- 429
+ + Q GL G S + PG PGP D L
Sbjct: 919 PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP----------PGPMDPNLLGSKGEKGE 968
Query: 430 PGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489
PG P +P + P Y PG P GQP L LP P
Sbjct: 969 PGLPG--IPGVSGPKG--YQGLPGDP----------GQPG------LSGQPGLPGP---- 1004
Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR----EKLPAVRSSQGGSP 545
P P G L P G P G +G +G G PGP+ P+ Q GSP
Sbjct: 1005 ---PGPKGNPGLPGQPGLIGPP----GLKGTIGDMG-FPGPQGVEGPPGPSGVPGQPGSP 1056
Query: 546 ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTC 605
L G D G P +S G P LP P+ E LP N
Sbjct: 1057 GLPGQKG--DKG---------DPGISSIGLPGLPGPK------GEPGLPGYPGNPGIKGS 1099
Query: 606 SSLSPMSSSPANPSSEESQ-------LPGPLGPSAFFHPPTHPQETGSPFP---SPEPPH 655
+ P P ++ PGP GP PP +P G P P P
Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159
Query: 656 SLPTHYQPEPAK-AFPFPADGLGAEGAFQCLEETPFPHEGP--------EVGRGGLQGFP 706
P + +P + P PA G G + F + GP + G GGL G P
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPG------QPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213
Query: 707 RAP 709
P
Sbjct: 1214 GNP 1216
Score = 78.2 bits (191), Expect = 2e-13
Identities = 175/691 (25%), Positives = 225/691 (32%), Gaps = 128/691 (18%)
Query: 1 MPGERPRGAPP----PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQ 56
+PGE+ PP P G+ + +PG P PP P G G+
Sbjct: 841 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMG 899
Query: 57 AMELPEAQPRQARDGELKPPSLRGQ----------APSSTPGKRGSPQTPPGRSPLQAPS 106
M P G P L+G P+ G +G P P P+ P+
Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-PN 958
Query: 107 RLAGRAE-GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG 165
L + E G P I G++ + L P P L P + P GP G P PG
Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ--PGLPGPPGP-KGNPGLPG 1015
Query: 166 LPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSY- 224
P P + + + P PP P + SP PG
Sbjct: 1016 QPGLIGPPGLK------------GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKG 1063
Query: 225 ----PEYQASGADSWP-PAAENSFPG--ANFGVPPAEPEPIPKGSRPG--GSPRGVSFQF 275
P + G P P E PG N G+ + +P PG G+P G Q
Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP----GLPGLPGTP-GAKGQP 1118
Query: 276 PFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPL 335
P G P P ++G G P P VG G P QP P
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPG-------LPGEPGP---VGGGGH---PGQPGP--- 1162
Query: 336 PCYQGQPG--GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGS 393
P +G+PG G+ + G PG + P + LP P GL
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP--GNPGLPG 1220
Query: 394 TRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT-PP 452
+G P FPG GPP GPP + P L P P P PP
Sbjct: 1221 PKGEPGF---HGFPGVQ----------GPP-------GPPGSPGPALEGPKGNPGPQGPP 1260
Query: 453 G--------GPLAATRSMFFNGQP-SPGQRLCLPQSAPLPWPQVLP-----TARPSPHGM 498
G GP + G+ +PGQ LP L Q P RP +GM
Sbjct: 1261 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQP-GLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1319
Query: 499 EMLSRLPFPAGGPEWQG--GSQGALGTAGK-----TPGPREKLPAVRSSQGGSPALFTYN 551
+ LP G P +G G G+ G G+ PGP P + G S +
Sbjct: 1320 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP----PGLPGPSGQSIIIKGDA 1375
Query: 552 GMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPM 611
G QP G+ PQ G LP P P + L P + AG
Sbjct: 1376 GPPGIPGQPGLKGLPGPQ----GPQGLPGPTGPPGDPGRNGL--PGFDGAGG-------R 1422
Query: 612 SSSPANPSSEESQ-LPGPLGPSAFFHPPTHP 641
P P ++ L GP GP PP P
Sbjct: 1423 KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1453
Score = 71.2 bits (173), Expect = 2e-11
Identities = 371/1591 (23%), Positives = 469/1591 (29%), Gaps = 326/1591 (20%)
Query: 2 PGERPR----GAP-PPTMTGDLQPRQVASSPGHPSQP--PLEDNTPATRTTKGAREAGGQ 54
PG R + G P PP G P + PG P P P D P + G G+
Sbjct: 71 PGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130
Query: 55 AQAMELPEAQPRQARDGELKPPSLRGQAPS----STPGKRGSP--QTPPGRSPLQAPSRL 108
P Q G P ++G+ S S PG +G+P PPG L P+ +
Sbjct: 131 RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGI 190
Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168
G P G+ P L N L Q P+ + + G P PG
Sbjct: 191 PGPIGPPGPP----GLMGPPGPPGLPGPKGNMGLNF-QGPKGEKGEQGLQGPPGPPGQIS 245
Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228
+ +P E F + Q P R P PGPP RG PG
Sbjct: 246 EQKRPIDVE--FQKGDQGLPGD-------------RGP-PGPPGIRGP----PG------ 279
Query: 229 ASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF 288
PP E G G P +P G G P G+ P G +
Sbjct: 280 -------PPGGEKGEKGEQ-GEPGKRGKPGKDGEN--GQP-GIPGLPGDPGYPGEPGRDG 328
Query: 289 PADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348
G GP +P G LP + P QG PG
Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG----- 383
Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS--AQDGLGSTRGPPSSLPQRHF 406
L G PGAA P PP + G GPP
Sbjct: 384 --LPGP---PGAAVMGP----------------PGPPGFPGERGQKGDEGPPGI----SI 418
Query: 407 PGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG 466
PG G+D PG P PGPP P + P PPG P +
Sbjct: 419 PGPP----GLDGQPGAP----GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470
Query: 467 QPSPGQR--LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTA 524
Q G + C + T P G L LP P G + G +G G A
Sbjct: 471 QGVKGDKGDTCF---------NCIGTGISGPPGQPGLPGLPGPPGSLGFPG-QKGEKGQA 520
Query: 525 GKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVA--QPQVSPHGTPSLPPPR 582
G T GP+ LP + + G +P G +PG F G+ + ++ G P LP
Sbjct: 521 GAT-GPKG-LPGIPGAPG-APGFPGSKG--EPGDILTFPGMKGDKGELGSPGAPGLPGLP 575
Query: 583 VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPG---PLGPSAFFHPPT 639
LP P G T +P P LPG P+GP F P
Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG-----LPGNIGPMGPPGFGPPGP 630
Query: 640 -----------HPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEET 688
+P + G P P +P ++ +P P +G G +
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG-LPGNPGRDGDVGLPGDPGLPGQP 689
Query: 689 PFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLA 748
P G G+ G PP P +
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP------------------------- 724
Query: 749 HRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGK 808
G + G + PGPPG P P P F L G G
Sbjct: 725 -----GAPGTPGRIGLEGPPGPPGFPGPKGEPG---------------FALPGPPGPPGL 764
Query: 809 DDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVF 868
P G L FP P LD L P+
Sbjct: 765 --PGFKGALGPKGDRGFPGPPGP---PGRTGLDGL------------PGPK--------- 798
Query: 869 ADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPA-RGRPKTR 927
D P+G GP G P GV PP P P P +PG G P +G P
Sbjct: 799 GDVGPNGQPGPM-GPPGLPGIGVQG-----PPGPPGIPGP-IGQPGLHGIPGEKGDPGPP 851
Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLG 987
L + + S G G G G G ASG P +G
Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPI-----------GPPGSPGLPGKAGASGF-PGTKGEMG 899
Query: 988 ERPPPRPRRP-----RTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042
PP P P R+ PG + D + LP T + P P
Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDG--LQGQPGLPGPTGEKGSKGEPGLPGPP----- 952
Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGP 1102
G L+ S+ E+ E P PG G +G QG
Sbjct: 953 -GPMDPNLL---------------GSKGEKGEPGLPGIPGVSGPKGY----------QGL 986
Query: 1103 REDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLE-TGAAAREGGP 1161
D Q G G NP PG +PG P +G + G EG P
Sbjct: 987 PGDPGQPGLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044
Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLD------FPQEAKEPETAEESAPDSTEFTE 1215
PS P P + ++ P + P EP P +
Sbjct: 1045 G----PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP--GYPGNPGIKG 1098
Query: 1216 ALRSPPA-ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLL 1274
++ P G GA +P P GTP P G + P G+ PG +
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPKGISGPPGNPGLPGEPGPV 1151
Query: 1275 GGPG--GTQAPVSHNSK------DPPARQPGEFLAP-VANPSSTACPKPSVLSSK--ISS 1323
GG G G P K PA Q GE P NP P S +
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPG 1211
Query: 1324 FGCDPA--GFNRDP--LGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDA 1379
+P G +P G P + P P SP L GPK G P +
Sbjct: 1212 IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL-EGPKGNPGPQGPPGRPGLPGPEG 1270
Query: 1380 PPASSSCLCQDGEDAGSLEPQLP--------RSPPGTAETEPGRAASPPTLESSSLFPDL 1431
PP GE +P LP + PPG + PGR P L P L
Sbjct: 1271 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG-LQGNPGR----PGLNGMKGDPGL 1325
Query: 1432 PVDRFDPPLYGSLSANRDSGLPFAC---ADPPQKTVPSDP--PYPSFLLLEEVSPMLPSH 1486
P P + G SG+P + +P P P P PS + P
Sbjct: 1326 PGVPGFPGMKG------PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG 1379
Query: 1487 FPDLSGGKVLSKTCPPERTVVPGAAPSLPGK 1517
P G K L P+ P P PG+
Sbjct: 1380 IPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR 1410
Score = 69.3 bits (168), Expect = 7e-11
Identities = 316/1310 (24%), Positives = 398/1310 (30%), Gaps = 204/1310 (15%)
Query: 309 PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGA-AHSAP 365
P+G ++ + GP P + P LP + G PG G+ H G PG
Sbjct: 73 PRGQKGDDGI-PGPPGPKGIRGPPG-LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130
Query: 366 RPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT 425
R F S P P GL GPP + PG +S PGP
Sbjct: 131 RGFPGS---------PGFP-----GLQGPPGPPGIPGMKGEPGSIIMSS----LPGPKGN 172
Query: 426 ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLP-------- 477
PGPP + L PT P P P GP G P P + L
Sbjct: 173 P-GYPGPPG--IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229
Query: 478 -----QSAPLPWPQVLPTARP----------------SPHGMEMLSRLPFPAGGPEWQGG 516
Q P P Q+ RP P G + P P GG + + G
Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289
Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPG--AQPLFFGVAQPQVSPHG 574
QG G GK PG + + G P + G DPG +P G + Q G
Sbjct: 290 EQGEPGKRGK-PG--------KDGENGQPGIPGLPG--DPGYPGEPGRDG-EKGQKGDTG 337
Query: 575 TPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634
P PP +V +P P T G T + E PG GP
Sbjct: 338 PPG--PPGLV--------IPRPGT---GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL 384
Query: 635 FHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEG 694
PP G P P P + P + P P GL + L P P G
Sbjct: 385 PGPP-GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLDGQPGAPGLPGPPGP-AG 441
Query: 695 PEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQLDVLLTCRQC-------DRNYSSLAAF 746
P + P P PP L + D TC C L
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501
Query: 747 LAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPA-DAHAGLLSHAKTFL-LAGDAQ 804
G + + G + GP GLP P AP P G TF + GD
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561
Query: 805 AEGKDDPLRTGFLPSLAATPFP--LPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDS 862
G P G LP L TP LP + + G NP +
Sbjct: 562 ELG--SPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGI------TFKGERGPPGNPGLPG 612
Query: 863 SFIDVFADEEPS-GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDP-----QTPRPGDR 916
++ P GP GP ++ AG + P +P DP Q +PG
Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAG----NPGQPGIPGPKGDPGQTITQPGKPGLP 668
Query: 917 GCPAR----GRPKTRSLGLAPTEADAP-SQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971
G P R G P L P P S+G G L G G+ G
Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728
Query: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRL 1030
GL E PP P P + PG P P R
Sbjct: 729 TPGRIGL---------EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779
Query: 1031 PPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRG 1090
P P R G G + + Q + + PP PG G+ G
Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839
Query: 1091 EKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL 1150
E P D P P R G GAP P P GS PG++ + P
Sbjct: 840 GIPGEKGDPGPPGLDVPGPP--GERGSPGIPGAP-GPIGPPGSPGLPGKAGASGFPGTKG 896
Query: 1151 ETGAAAREGG------PKCADRPSVAPKDPLQ----VPTNT-ETSEETRPSLDFPQEAKE 1199
E G G P + P + D LQ +P T E + P L P +
Sbjct: 897 EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956
Query: 1200 P-------ETAEESAP-----DSTEFTEALRSPPAACAGEMGAS--PGLLIPEQP----- 1240
P E E P + + L P G+ G S PGL P P
Sbjct: 957 PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP----GQPGLSGQPGLPGPPGPKGNPG 1012
Query: 1241 -PPSRHDTGTPKPSGSLAN---TAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQ- 1295
P G P G++ + P G PG + G PG P K P
Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072
Query: 1296 ---PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPH 1352
PG P P P + + DP G P G P AK P P
Sbjct: 1073 IGLPG-LPGPKGEPGLPGYPGNPGIKGSVG----DP-GLPGLP-GTPGAKGQPGLPGFPG 1125
Query: 1353 SELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETE 1412
+ GPK ++G PP + + G G P P PPG + +
Sbjct: 1126 TPGPPGPKGISG---------------PPGNPGLPGEPGPVGGGGHPGQP-GPPG-EKGK 1168
Query: 1413 PGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANR-DSGLPFACADPPQKTVPSDPPYP 1471
PG+ P PP LS + D GLP +P +P +
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228
Query: 1472 SFLLLEEVSPMLPSHFPDLSGGK-VLSKTCPPERTVVPG--AAPSLPGKG 1518
F ++ S P L G K PP R +PG P LPG G
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNG 1278
Score = 57.8 bits (138), Expect = 2e-07
Identities = 134/539 (24%), Positives = 157/539 (29%), Gaps = 130/539 (24%)
Query: 12 PTMTGDLQPRQVASSPGHPSQPPL--EDNTPATRTTKGAREAGGQAQAMELPEAQPRQAR 69
P + G P+ PG P QP L + P KG GQ + P +
Sbjct: 972 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031
Query: 70 DGELKPPSLRGQ-APSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSR 128
G P + G PS PG+ GSP P + P + G P G+ +
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI---SSIGLP------GLPGPK 1082
Query: 129 TKPTLDETPENPQLEAAQLPEVDTPQGPGT-GAPLRPGLPRTEAQPAAEELGFHRCFQEP 187
+P L P NP ++ + + + P PGT GA +PGLP P P
Sbjct: 1083 GEPGLPGYPGNPGIKGS-VGDPGLPGLPGTPGAKGQPGLPGFPGTPG------------P 1129
Query: 188 PSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP-PAAENSFPGA 246
P + P P P P G P QPG E G D P PA + PG
Sbjct: 1130 PGP---KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQ 1186
Query: 247 -NFGVP--------------------PAEPE-PIPKGSR----------PGGSPRGVSFQ 274
FG P P P P PKG P G P
Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS---- 1242
Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTG-PAYP-LPTQPAP 332
P PAL G P P G GP G E G P P LP
Sbjct: 1243 -PGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1301
Query: 333 SPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS- 386
P QG PG G+ L G PG + P S I P PP
Sbjct: 1302 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1361
Query: 387 --------------------AQDGLGSTRGP--PSSLP---------------------- 402
Q GL GP P LP
Sbjct: 1362 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1421
Query: 403 ---QRHFPGQAYRAS--------GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT 450
PGQ G+ PGPP T A G R Q D P T
Sbjct: 1422 RKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1480
Score = 53.5 bits (127), Expect = 4e-06
Identities = 263/1154 (22%), Positives = 343/1154 (29%), Gaps = 270/1154 (23%)
Query: 1751 EPGTADQPHR----GAPA-PEAFGSPAVHLAP----DLAFQGDGAPPLDATWPFGASPSH 1801
EPG +P + G P P G P P + +GD PP P G
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPP----GPPGLVIPR 348
Query: 1802 AAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVSNT 1859
G + G G P G PG +G P G L P G P P
Sbjct: 349 PGTGITIGEKGNIGLP--GLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG------ 400
Query: 1860 HPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPS--------- 1910
P R Q PP + +PGP + G GL P + P + PS
Sbjct: 401 FPGERGQKGDEGPP--GISIPGPPGLDGQPGAPGLPG--PPGPAGPHIPPSDEICEPGPP 456
Query: 1911 ---------GLEGGT-VEGGK---------VACGPAQGSPGGVQVTTLPAVAGHQLGLEA 1951
GL+G V+G K G PG LP + G L
Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPG------LPGLPGPPGSLGF 510
Query: 1952 DGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKC 2011
G G GQA T +G P +PG S P LT P
Sbjct: 511 PGQKGEKGQAGATGPKGL-----PGIPGAPGAPGFPGS-KGEPGDILTFPG--------M 556
Query: 2012 KGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLAT 2071
KG + + SP +P L TP + PGL P
Sbjct: 557 KGDKGELG---------SPGAPGLPGLP--------------GTPGQDGLPGLPGPK--- 590
Query: 2072 GDSPAPSVGDLAACAPSPTSAAHMPCSLGPL--PREDPLTSPSRAQG--GLGGQLPASPS 2127
P P +P ++GP+ P P P +G G+ G P P
Sbjct: 591 -GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP-PGPVGEKGIQGVAGN-PGQPG 647
Query: 2128 CRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAP--PSLTTSPCDPKE-ALAG 2184
P G P L G D G P P P L P E + G
Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDG--DVGLPGDPGLPGQPGLPGIPGSKGEPGIPG 705
Query: 2185 CLLQGEGSPLEDPS-SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243
L G P P PPG+ P P+ L PG P
Sbjct: 706 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765
Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSP 2303
GA+ P GD RG PGP G P T D +P P
Sbjct: 766 GFKGALGPK-------------GD-----RGFPGPP----GPPGRTGLDGLPGPKGDVGP 803
Query: 2304 SNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK-----EPEDPGTP--- 2355
+ GQ P P + GP P + G +G E DPG P
Sbjct: 804 N---------GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD 854
Query: 2356 ---ETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLG 2412
G G+ +P P +G +P S P + P G P G
Sbjct: 855 VPGPPGERGSPGIPGAPGP-----IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP-G 908
Query: 2413 PQDLKQRS-----------RGYKKKPASTENGQWKGQ----APHGPVTCEVCAASFRSG- 2456
P + RS +G P T KG+ P GP+ + + G
Sbjct: 909 PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE 968
Query: 2457 ------PGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKER 2510
PG+S K ++ PG P +P + P G
Sbjct: 969 PGLPGIPGVSGPKG--YQGLPGDPGQPGLSGQP-----------------------GLPG 1003
Query: 2511 PNHSRGDPSHVTQP----PPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRP 2566
P +G+P QP PP G K + G P Q + P P P
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPP--GLKGTIGDMGFPGPQGVEGP-----------PGPSGVP 1050
Query: 2567 DQAREDELHPKQAEKREGRRWRREPTVDS---PSHSEGKSNKKRGKLRGRRLREESILPV 2623
Q L ++ +K + P + S P K G + S+
Sbjct: 1051 GQPGSPGLPGQKGDKGD-------PGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103
Query: 2624 SADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLG-PGVMEGAAETD 2682
+ G++ P + + +P GP+ P G PG + G
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPG-----PPGPKGISGPPGNPGLPGEPGPVGGG---- 1154
Query: 2683 QEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGASAR-GFWGPRETKALGVCKE 2741
G G PPG++ PG+ DG P GQKG + GF P G+ +
Sbjct: 1155 ------GHPGQPGPPGEKGK-PGQ-DGIP---GPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203
Query: 2742 SGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPAD-STTSSCLQGLPDNPDTQ 2800
G D G+ P G GFP P + L+G NP Q
Sbjct: 1204 KG-----DGGLPGIPGNPGLPGPKGEP-GFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257
Query: 2801 G-----GVQGPEGP 2809
G G+ GPEGP
Sbjct: 1258 GPPGRPGLPGPEGP 1271
Score = 52.0 bits (123), Expect = 1e-05
Identities = 117/458 (25%), Positives = 144/458 (31%), Gaps = 74/458 (16%)
Query: 3425 VRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLC 3484
+ +PG PG L G P + V +PG PG+ P G E +P +
Sbjct: 659 ITQPGKPG-----LPGN-PGRDGDVGLPGDPGLPGQPGLP--GIPGSKGEPGIPGI---- 706
Query: 3485 SEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALD 3544
P KG+P P P T G E P P P P AL G L
Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP-GFALPGPPGPPGLP 765
Query: 3545 G---ALERPENEASPGSPGPLLQQALPLGASLPRP----GARGQDAEGKRAPLVFSGKRR 3597
G AL + PG PGP + L LP P G GQ L G +
Sbjct: 766 GFKGALGPKGDRGFPGPPGPPGRTGLD---GLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822
Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSA 3657
PG G P H + EK + GP G +GS P
Sbjct: 823 PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG--ERGSPGIPG----------- 869
Query: 3658 ASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717
A P P P KA S PG T+ M P PGP S PG K
Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPG-----TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924
Query: 3718 GGSQPQPA-------SGQLQSETATTPAKPSFPS--------RSPAPERLPARAQAKSCT 3762
G Q QP G P P P+ P +P + K
Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984
Query: 3763 KGPREAGEQGPHGSLG----PKEKGESSTKRKKGQVPGPARSESVGSFG-RAPSAPDKPP 3817
P + G+ G G G P KG + G + P ++G G P + PP
Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044
Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855
PS V P P P + K +PG
Sbjct: 1045 -------GPSGV------PGQPGSPGLPGQKGDKGDPG 1069
Score = 51.6 bits (122), Expect = 2e-05
Identities = 170/687 (24%), Positives = 226/687 (32%), Gaps = 102/687 (14%)
Query: 871 EEPSGPRGPSSGHPLKSKAGVTPES-KAPPPLPAATPDPQTP-RPGDRGCPA-RGRPKTR 927
E P GPRG + G P+ + PP LP P P PG G P +G P
Sbjct: 68 EGPPGPRGQKGDDGIPGPPG--PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIP--- 122
Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR-PRRNDGL 986
G T+ + G G Q G G G S L P+ N G
Sbjct: 123 --GCNGTKGERGFPGSPGFPGLQ-----GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY 175
Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046
P + T PG P P P + + P+ K G
Sbjct: 176 PGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235
Query: 1047 GKELILKIVQQKNRLREYDFASESE--EDEQPPPRGPGFRGRRG--RGEKRKEVELTQGP 1102
G + ++ R + +F + ++ PP PG RG G GEK ++ E
Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----- 290
Query: 1103 REDEPQKPRKAARQ-EAGGDGAPANPEEPGGSRPG-PGRSPQARGPSRSLETGAAAREG- 1159
+ EP K K + E G G P P +PG PG PGR + + +TG G
Sbjct: 291 -QGEPGKRGKPGKDGENGQPGIPGLPGDPG--YPGEPGRDGE---KGQKGDTGPPGPPGL 344
Query: 1160 -GPKCADRPSVAPKDPLQVP-TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217
P+ ++ K + +P E E P + P P A P
Sbjct: 345 VIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG------- 397
Query: 1218 RSPPAACAGEMG-----ASPGLLIPEQP-----PPSRHDTGTPKPSG-------SLANTA 1260
P GE G PG+ IP P P + G P P+G +
Sbjct: 398 ---PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454
Query: 1261 PHGSSPTPGVGSLLGGPG--GTQAPVSHN----SKDPPARQPGEFLAPVANPSSTACPKP 1314
P G +PG L G G G + N P QPG P P S P
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP-GPPGSLGFPGQ 513
Query: 1315 SVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL-FLGPKDLAGCFLEELHPK 1373
+ + G P G P G P A P P L F G K G EL
Sbjct: 514 KGEKGQAGATG--PKGLPGIP-GAPGAPGFPGSKGEPGDILTFPGMKGDKG----EL-GS 565
Query: 1374 PSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPG--TAETEPGRAASPPTLESSSLFPDL 1431
P A P + G+D P P+ PG T + E G +P P L
Sbjct: 566 PGAPGLPGLPGT----PGQDGLPGLPG-PKGEPGGITFKGERGPPGNPG-------LPGL 613
Query: 1432 P--VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD 1489
P + PP +G + G+ +P Q +P P + + P LP + P
Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN-PG 672
Query: 1490 LSGGKVLSKTCPPERTVVPGAAPSLPG 1516
G L P +PG P LPG
Sbjct: 673 RDGDVGL-----PGDPGLPG-QPGLPG 693
Score = 49.7 bits (117), Expect = 6e-05
Identities = 120/515 (23%), Positives = 165/515 (32%), Gaps = 81/515 (15%)
Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLP 3478
P ++G+ PG PGQ + + LP PG PG PP G + + P
Sbjct: 980 PKGYQGL--PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP--GLKGTIGDMGFP 1035
Query: 3479 ALLHLCSEVAPSTTKGWPETLERPV------DPVTHPIRGCELPSNHQECPPPSLSPFPA 3532
+ PS G P + P DP I LP E P L +P
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE---PGLPGYP- 1091
Query: 3533 ALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG-------QDAE 3584
G+ + G++ P PG+PG Q LP P PG +G
Sbjct: 1092 ------GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145
Query: 3585 GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATK 3644
G+ P+ G PG G E ++ + E G G + G
Sbjct: 1146 GEPGPVGGGGHPGQPGPPG--------EKGKPGQDGIPGPAGQKGEPGQPGFGNPG---- 1193
Query: 3645 PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSS 3704
P G S + P P +P PG G P P PGP+
Sbjct: 1194 PPGLPGLSGQKGDGGLPG----IPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPAL 1247
Query: 3705 QG-SGSP-------RPGTKTGGGSQPQPASGQLQSETATTPAKPSFP--------SRSPA 3748
+G G+P RPG G P +G ++ E P +P P P
Sbjct: 1248 EGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKG-NPGQPGLPGLPGLKGDQGPPG 1306
Query: 3749 PERLPARAQAKSCTKGPREAGEQGPHGSLGPK-EKGESSTKRKKGQV--------PGPA- 3798
+ P R P G G G GP G + + + G + PGP+
Sbjct: 1307 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1366
Query: 3799 RSESVGSFGRAPSAPDKP--PRTPRKQATPSRVLPTKP--KPNSQNKPRPPPSEQRKAEP 3854
+S + P P +P P Q PT P P P + RK +P
Sbjct: 1367 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1426
Query: 3855 GHTQRKDRLGKAFPQGRPLLR----PPKRGTAVHG 3885
G + G P G L+ PP + HG
Sbjct: 1427 GLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHG 1461
Score = 47.8 bits (112), Expect = 2e-04
Identities = 113/463 (24%), Positives = 147/463 (31%), Gaps = 74/463 (15%)
Query: 3432 GQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPST 3491
G K E P +PG PGP E P PRG + +P P
Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGF-PGP-EGPPGPRGQK---GDDGIPGPPGPKGIRGPPG 96
Query: 3492 TKGWPETLERPV------DPVTHPIRGCELPSNHQECPP----PSLS--PFPAALADGRG 3539
G+P T P P I GC + P P L P P + +G
Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156
Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-------------RPGARGQDAEGK 3586
+ P + +PG PGP Q LP +P PG G
Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216
Query: 3587 RAPLVFSGKRRAPGARGRCAP-----DHFQEDHLLQKEKEVSSSHMVSEGGPRG-TFHKG 3640
L F G + G +G P ++ + E + + + GP G +G
Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276
Query: 3641 SATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA-----PGELARGTENGMKPAT 3695
P G + ++ K K + + + L PGE R E G K T
Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT 336
Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755
PGP G PRPGT G + L E + FP P LP
Sbjct: 337 --GPPGP--PGLVIPRPGTGITIGEKGNIGLPGLPGE----KGERGFPG-IQGPPGLP-- 385
Query: 3756 AQAKSCTKGPREAGEQGPHGSLG-PKEKGESSTKRKKG-QVPGPARSESVGSFGRAPSAP 3813
GP A GP G G P E+G+ + G +PGP + P AP
Sbjct: 386 --------GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG------QPGAP 431
Query: 3814 DKP-PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855
P P P P +P P P PP S K G
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGP-----PGPPGSPGDKGLQG 469
Score = 47.8 bits (112), Expect = 2e-04
Identities = 114/477 (23%), Positives = 150/477 (31%), Gaps = 62/477 (12%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS-EGSLPALLHLCSE 3486
PG+PG +A P + + M G PG P R P L + L L
Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936
Query: 3487 VAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546
+KG P L P P+ + G + E P L P ++ +G L G
Sbjct: 937 TGEKGSKGEPG-LPGPPGPMDPNLLGSK-----GEKGEPGLPGIPG-VSGPKGYQGLPGD 989
Query: 3547 LERPENEASPGSPGPLLQQALPLGASLPR----PGARG----------QDAEGKRAPLVF 3592
+P PG PGP + P P PG +G Q EG P
Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049
Query: 3593 SGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSS 3652
G+ +PG G+ + + +SS + GP+G G + S
Sbjct: 1050 PGQPGSPGLPGQKGD---------KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV 1100
Query: 3653 KDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP 3712
D P A G PG G P PK GP P
Sbjct: 1101 GDPGLPGLPGTP--------GAKGQ--PG--LPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148
Query: 3713 GTKTGGGSQPQPA----SGQLQSETATTPA----KPSFPS-RSPAPERLPARAQAKSCTK 3763
G GGG QP G+ + PA +P P +P P LP + K
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208
Query: 3764 GPREAGEQGPHGSLG-PKEKGESSTKRKKGQ--VPGPARSESVGSFGRAPSAPDKPPRTP 3820
P G G G G P G + G PGPA G+ G P P P P
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG--PQGPPGRPGLP 1266
Query: 3821 RKQATP-----SRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
+ P + K P P P + + PG R G +G P
Sbjct: 1267 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDP 1323
Score = 44.7 bits (104), Expect = 0.002
Identities = 115/475 (24%), Positives = 140/475 (29%), Gaps = 62/475 (13%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG PG + LP PG GE PP P L L +
Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN-----------PGLPGLPGNI 617
Query: 3488 APSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546
P G+ P PV I+G P P P G+ L G
Sbjct: 618 GPMGPPGF-----GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP--GLPGN 670
Query: 3547 LERPENEASPGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF---SGKRRAPGAR 3602
R + PG PG Q LP + S PG G G P F G APG
Sbjct: 671 PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730
Query: 3603 GRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS 3662
GR + K + GP G A P G DR P
Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPG 784
Query: 3663 ----------KALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP 3712
K V P G + P L G P P PGP Q P
Sbjct: 785 PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG--PPGPPGIPGPIGQPGLHGIP 842
Query: 3713 GTKTGGGSQPQPASGQL-QSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ 3771
G K G G + + P P P P LP +A A E G
Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMM 901
Query: 3772 GPHGSLGPKE----------KGESSTKRKKGQVPGPARSESVGSFGR----APSAPDKPP 3817
GP G GP KG+ + + G +PGP + GS G P P P
Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEK--GSKGEPGLPGPPGPMDPN 958
Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
K LP P + + P + +PG + + G P+G P
Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLPGPPGPKGNP 1011
Score = 43.1 bits (100), Expect = 0.005
Identities = 205/900 (22%), Positives = 270/900 (30%), Gaps = 129/900 (14%)
Query: 1684 GDSRPPQD-VCLPEPSKQPGPQLDAGSLAK---CSPDQELSFPKNKEAASSQESEDSLRL 1739
G PP D +C P P PG D G + + F S + L
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500
Query: 1740 LPCEQRGGFLPEPG-TADQPHRGAPAPEAFGSPAVHLAPDL-AFQGDGAPPLDATWPFGA 1797
LP G L PG ++ GA P+ G P + AP F G P D F
Sbjct: 501 LPGPP--GSLGFPGQKGEKGQAGATGPK--GLPGIPGAPGAPGFPGSKGEPGDIL-TFPG 555
Query: 1798 SPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLV------PVP 1851
+ S G G G PG G + G L P+G + P
Sbjct: 556 MKGDKGELGSPGAPG-----LPGLPGTPGQD----GLPGLPGPKGEPGGITFKGERGPPG 606
Query: 1852 SPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGL--QELTPAAQSPP---- 1905
+P P + PP PGP K G+ G Q P + P
Sbjct: 607 NPGL-----PGLPGNIGPMGPP--GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659
Query: 1906 -RVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQ----LGLEA-DGHWGLLG 1959
+ GL G G V G PG + +P G +GL G G G
Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719
Query: 1960 QAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMS 2019
GT ++ E P G P AL GP L G + A+
Sbjct: 720 IPGPPGAPGTPGRIGLE---GPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGALG 772
Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSV 2079
+ + P PP P + L G G+ P PGL P + P P
Sbjct: 773 PKGD-RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGL--PGIGVQGPPGPP- 827
Query: 2080 GDLAACAPSPTSAAH-MPCSLG-PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137
P H +P G P P + P +G G +P +P PPG
Sbjct: 828 ---GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG--IPGAPGPIGPPG---- 878
Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCL----LQGE--- 2190
SP A G T P PP P + + G LQG+
Sbjct: 879 ---SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP--GRSGVPGLKGDDGLQGQPGL 933
Query: 2191 -------GSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243
GS E PPG + G+ + IP S + PG P
Sbjct: 934 PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993
Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPG-------PDPQSRGAPPHTNPDRMPR 2296
L+G G P GL G P PQ PP P +P
Sbjct: 994 GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP--GPSGVP- 1050
Query: 2297 GHSSYSPSNTARLGHREGQAVTAV-------PTEPPTLQGAGPDSPACLEGEMGTSSKEP 2349
SP + G + ++++ P P L G P +P ++G +G P
Sbjct: 1051 -GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY-PGNPG-IKGSVGDPGL-P 1106
Query: 2350 EDPGTP-ETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQG 2408
PGTP G+ G P P G+ + P + + + P G
Sbjct: 1107 GLPGTPGAKGQPGLPGFPGTPGPPGPKGI--SGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164
Query: 2409 DPLGP-QDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKH 2467
+ P QD G K +P G P G PGLS K
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFG---NPGPPGL-------------PGLSGQKGDGG 1208
Query: 2468 RPH-PGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPP 2526
P PG P P P P + PP + G + +G P P P
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGP 1268
Score = 40.4 bits (93), Expect = 0.035
Identities = 56/209 (26%), Positives = 69/209 (33%), Gaps = 18/209 (8%)
Query: 3693 PATPKAKPGPSSQGSG---SPRPGTKTGGGSQPQPASGQLQSETATT----PAKPSFPSR 3745
P P PG + S PG K G P L T P P
Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204
Query: 3746 SPAPERLPA-RAQAKSCTKGPR-EAGEQGPHGSLGP-----KEKGESSTKRKKGQ--VPG 3796
P P LP + +GP+ E GEQG G GP ++K + +KG +PG
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264
Query: 3797 PARSESVGSFGRAPSAPDKPPRTPRKQATPS-RVLPTKPKPNSQ-NKPRPPPSEQRKAEP 3854
P P +Q P R P K N Q P P EP
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324
Query: 3855 GHTQRKDRLGKAFPQGRPLLRPPKRGTAV 3883
G K + G P G P L P+ GT +
Sbjct: 325 GRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353
Score = 37.7 bits (86), Expect = 0.23
Identities = 50/197 (25%), Positives = 62/197 (31%), Gaps = 35/197 (17%)
Query: 489 PTARPSPHGMEMLSRLPFPAG-----GPEWQGGSQGALGTAGK-----TPGPREKLPAVR 538
P P P G + +P P G GP G G G G PGP + +P
Sbjct: 67 PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP-QGIPGCN 125
Query: 539 SSQG-----GSPALFTYNGMTDPGAQPLFFG-----VAQPQVSPHGTPSLPPPRVVGASP 588
++G GSP G P P G + P G P P P + P
Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP 185
Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSA--FFHPPTHPQETGS 646
+ +P P P P P LPGP G F P E G
Sbjct: 186 GPTGIPGPIGPPG-------PPGLMGPPGPPG----LPGPKGNMGLNFQGPKGEKGEQGL 234
Query: 647 PFPSPEPPHSLPTHYQP 663
P P PP + +P
Sbjct: 235 QGP-PGPPGQISEQKRP 250
Score = 37.0 bits (84), Expect = 0.39
Identities = 169/712 (23%), Positives = 217/712 (30%), Gaps = 136/712 (19%)
Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASA 3265
P P+ G R G PG P + PG P P + DGA P
Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH-DGAPGPQGIPG 123
Query: 3266 T--ALADAGSPGPP-----RTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCG--- 3315
+ G PG P + P P P GEP + + + P + + G
Sbjct: 124 CNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKGNPGYPGPPG 180
Query: 3316 -KRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLY 3374
+ P P + + P + P P + G + + G G LQ P
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240
Query: 3375 ACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGAP--G 3432
++ I + F K +Q L G R P G+R P P G
Sbjct: 241 PGQISEQKRPI----------DVEFQKGDQ-------GLPGDRGPPGPPGIRGPPGPPGG 283
Query: 3433 QKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTT 3492
+K E P KR + PG+D E P +
Sbjct: 284 EKGEKGEQGEPGKRGK---------PGKD-----------GENGQPGI------------ 311
Query: 3493 KGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA--LADGRGDCALDGAL--- 3547
G P P +P +G + PP + P P +G+ L G
Sbjct: 312 PGLPGDPGYPGEPGRDGEKG-QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370
Query: 3548 -ER--PENEASPGSPGPLLQQALPLGASLPR--PGARGQDAEGKRAPLVFS-----GKRR 3597
ER P + PG PGP A +G P PG RGQ +G P S G
Sbjct: 371 GERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQ--KGDEGPPGISIPGPPGLDG 426
Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR-- 3655
PGA G P H + S + E GP G G Q D+
Sbjct: 427 QPGAPGLPGPPGPAGPH-------IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479
Query: 3656 -------SAASTPSKALKFPVHPRKAVGSLA----PGELARGTENGMK--PATPKAKPGP 3702
+ S P P P GSL GE + G K P P A P
Sbjct: 480 TCFNCIGTGISGPPGQPGLPGLPGPP-GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538
Query: 3703 SSQGS-GSPR-----PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756
GS G P PG K G P + L T P + P P P+ P
Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGL-PGPKGEPGGI 596
Query: 3757 QAKSCTKGPR----------EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSF 3806
K +GP G GP G P GE + G P G
Sbjct: 597 TFKG-ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655
Query: 3807 GRAPSAPDKP--PRTPRKQATPSRVLPTKP-KPNSQNKPRPPPSEQRKAEPG 3855
G+ + P KP P P + LP P P P P S K EPG
Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVG--LPGDPGLPGQPGLPGIPGS---KGEPG 702
Score = 34.3 bits (77), Expect = 2.5
Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 16/133 (12%)
Query: 3183 LGDLPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240
L LPG G +G + + P PK G G PG G + PG
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164
Query: 3241 ERAKPRARSTPS--------NPDGAATPDSASATALA----DAGSPGPPRT--TPSPSPD 3286
E+ KP P G P L+ D G PG P P P +
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224
Query: 3287 PWAGGEPLLQATP 3299
P G P +Q P
Sbjct: 1225 PGFHGFPGVQGPP 1237
Score = 34.3 bits (77), Expect = 2.5
Identities = 73/312 (23%), Positives = 92/312 (29%), Gaps = 61/312 (19%)
Query: 1623 QGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQA 1682
+G PG P +PG L + + G P P P K G
Sbjct: 1181 KGEPGQ----PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL---PGPKGEPGFHGFPGV 1233
Query: 1683 EGDSRPPQDV--CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLL 1740
+G PP L P PGPQ G P+ P N
Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGN---------------- 1277
Query: 1741 PCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPS 1800
GG E G QP G P G P + +GD PP G +
Sbjct: 1278 -----GGIKGEKGNPGQP--GLP-----GLPGL--------KGDQGPP-------GLQGN 1310
Query: 1801 HAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTH 1860
G + + L G PG +G P+G P G E L+ P P +
Sbjct: 1311 PGRPGLNGMKGDPGLPGVPGFPGMKG----PSGVPGSAGPEG-EPGLIGPPGPPGL---- 1361
Query: 1861 PSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGG 1920
P Q + +PG K G G Q L P +GL G GG
Sbjct: 1362 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1421
Query: 1921 KVACGPAQGSPG 1932
+ G PG
Sbjct: 1422 RKGDPGLPGQPG 1433
Score = 33.9 bits (76), Expect = 3.3
Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 16/121 (13%)
Query: 3186 LPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAKKDS 3238
LPG GL G + + + P P+ G G PG P G +G+ S
Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072
Query: 3239 PGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQAT 3298
G P + P P P ++ D G PG P T P A G+P L
Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKG--SVGDPGLPGLPGT-------PGAKGQPGLPGF 1123
Query: 3299 P 3299
P
Sbjct: 1124 P 1124
Score = 33.1 bits (74), Expect = 5.6
Identities = 22/55 (40%), Positives = 22/55 (40%), Gaps = 3/55 (5%)
Query: 1232 PGLLIPEQPPPSRH---DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283
PG PE PP R D G P P G P G PG L G PG AP
Sbjct: 62 PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 102 bits (255), Expect = 6e-21
Identities = 353/1470 (24%), Positives = 442/1470 (30%), Gaps = 295/1470 (20%)
Query: 4 ERPRGAPPPTMTGDLQPRQVASSPGHPSQ-----PPLEDNTPATRTTKGAREAGGQAQAM 58
E P+G PP GD PG P PP P G G
Sbjct: 69 EGPQG--PPGQKGD------TGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPP 120
Query: 59 ELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQA-PSRLAGRAEGSPP 117
+P + G L PP L PG G+P PPG ++ P + G G
Sbjct: 121 GIPGCNGTKGERGPLGPPGL--------PGFAGNP-GPPGLPGMKGDPGEILGHVPG--- 168
Query: 118 QRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPG--TGAPLRPGLPRTEAQPAA 175
+ + R P + TP P LP + P GP TG P PG P P
Sbjct: 169 ----MLLKGERGFPGIPGTPGPP-----GLPGLQGPVGPPGFTGPPGPPGPP----GPPG 215
Query: 176 EELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSW 235
E+ FQ P + P P PG Q + + G + G
Sbjct: 216 EKGQMGLSFQGPKGDKGDQGVSGP-----PGVPGQAQVQ-----EKGDFATKGEKGQKGE 265
Query: 236 PPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFP-FPALHGASTKPFPADVAG 294
P PG P +P P K + G S FP P G + P G
Sbjct: 266 P--GFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKG 323
Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVGTGP-------AYPLPT----QPAPSPLPCYQGQPG 343
A GP P +GTGP YP +P P P GQPG
Sbjct: 324 EAGPPGP------------PGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPG 371
Query: 344 --GLNRHSDLSGALSSPG-AAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSS 400
GL +GA PG R F + LP PS +DGL G P
Sbjct: 372 PPGLPVPGQ-AGAPGFPGERGEKGDRGFPGT-------SLP--GPSGRDGLPGPPGSPGP 421
Query: 401 LPQRHFPGQAYRASG-VDTSPGPPDTELAAPGPP--PARLPQLWDP----------TAAP 447
PGQ +G V+ PGPP + PG P P + ++ +
Sbjct: 422 ------PGQPGYTNGIVECQPGPPGDQ-GPPGIPGQPGFIGEIGEKGQKGESCLICDIDG 474
Query: 448 YPTPPGGPLAATRSMFFNGQPSPGQRLCLPQS---APLPWPQVL------PTARPSPHGM 498
Y PP GP + F GQP LP A +P PQ P A+ P
Sbjct: 475 YRGPP-GPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEF 533
Query: 499 EMLSRLPFPAGGPEWQG--GSQGALGTAGK-----TPGPREKLPAVRSSQGGSPALFTYN 551
RL G P + G G G G+ G+ PGP+ GSP
Sbjct: 534 YFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPK-----------GSPGSVGLK 582
Query: 552 GMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVG--------ASPSESPLPSPATNTAGS 603
G P F G ++ P G P P +G P LP P
Sbjct: 583 GERGPPGGVGFPG-SRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEP--- 638
Query: 604 TCSSLSPMSSSPANPSSEESQ-LPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQ 662
+ P+ P S PGP G F P P G +P P
Sbjct: 639 --GKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPG 696
Query: 663 PEPAKAFPFPADGLGAEG--AFQCLEETP---FPHEGPEVGRGGLQGFPRAP--PPYPTH 715
P+ P G G F L P P VG GL+G P P P P
Sbjct: 697 PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756
Query: 716 HFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPS 775
S+ + G + G + PGPPGLP
Sbjct: 757 KGSIGVPGVPGEH-------------------------GAIGPPGLQGIRGEPGPPGLPG 791
Query: 776 PPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPL----RTGFLPSLAATPFPLPASD 831
+P VP G G G P GF P P P D
Sbjct: 792 SVGSPGVPGIGPPGARGP------PGGQGPPGLSGPPGIKGEKGF-PGFPGLDMPGPKGD 844
Query: 832 LDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGV 891
+ L G+ QS P + P P P S K + GV
Sbjct: 845 KG-----------AQGLPGITGQSGLPGLPGQ------QGAPGIPGFPGS----KGEMGV 883
Query: 892 TPESKAPPPLPAATPDPQTP-RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQ 950
+ P P P P GD G P P+ G + D G + G
Sbjct: 884 M-GTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPR----GDPGLKGDKGDVGLPGKPGSM 938
Query: 951 LKLFRKDLDSGGAAEG-SGSGGGGRASGLRPRRND-GLGERPPPRPRRPRTQAPGSRADP 1008
K+ D+ S +G G G G + R D G P + + PG + DP
Sbjct: 939 DKV---DMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDP 995
Query: 1009 A-PRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFA 1067
P A LP S LP + G G + D
Sbjct: 996 GISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGL-----------PGDKG 1044
Query: 1068 SESEEDEQPPP--RGPGFRGRRG----------RGEKRKEVELTQGPREDEPQKPRKAAR 1115
++ E+ + PP PG RG +G GEK ++ + P K +
Sbjct: 1045 AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP--GLKGSP 1102
Query: 1116 QEAGGDGAPANPEEPGG-SRPG----PGRSPQARGPSRSLETGAAAREGGPKCADRPSVA 1170
G G+P P E G PG PG +A P TG A ++G P P A
Sbjct: 1103 GSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSA 1162
Query: 1171 PKDPLQVPTNTETSEETRPSLDFP------------QEAKEPETAEESAPDSTEFTEALR 1218
E E P FP E P A ++ +
Sbjct: 1163 ----------GEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFM 1212
Query: 1219 SPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGG 1276
PP G+ G SPG E P R G P G P G GV G
Sbjct: 1213 GPPGP-QGQPGLPGSPG-HATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGN 1270
Query: 1277 PGGTQAPVSHNSKDPPARQ--PGEFLAPVANPSSTACPKPSV--LSSKISSFGCDPAGFN 1332
PG AP K P Q PG +P S P V G +
Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330
Query: 1333 RDPLGVPVAKKGPQPYSSPHSELFLGPKDL 1362
+ GVP AK P P P GP D+
Sbjct: 1331 QGDQGVPGAKGLPGPPGPP------GPYDI 1354
Score = 83.6 bits (205), Expect = 4e-15
Identities = 327/1407 (23%), Positives = 440/1407 (31%), Gaps = 280/1407 (19%)
Query: 2 PGERPR-GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTP-ATRTTKGAREAGGQAQAME 59
PGE+ + G GD + V+ PG P Q +++ AT+ KG + G
Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGF----- 268
Query: 60 LPEAQPRQARDGELKPPSLRGQ-APSSTPGKRGSPQTP-----PGRSPLQAPSRLAGRAE 113
+ P GE P RG+ G++GSP P PG Q P G A
Sbjct: 269 --QGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAG 326
Query: 114 GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQG-PGT----GAPLRPGLPR 168
P ++G T P L E E P P+G PG G P +PG P
Sbjct: 327 PPGPPGIVIG-----TGP-LGEKGERGY------PGTPGPRGEPGPKGFPGLPGQPGPPG 374
Query: 169 TEAQPAAEELGFH-RCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEY 227
A GF ++ F T+ PS R PGPP S G
Sbjct: 375 LPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSG--RDGLPGPPGSPG------------ 420
Query: 228 QASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287
PP PG G+ +P P P P G P F
Sbjct: 421 --------PPGQ----PGYTNGIVECQPGP-PGDQGPPGIPGQPGFIGEIGEKGQKGESC 467
Query: 288 FPADVAGHAFTNGPLVFAFHQPQG--AWPEEAVGTGPAYPLPTQ------PAPSPLPCYQ 339
D+ G+ GP P G +P + G LP + P P P
Sbjct: 468 LICDIDGYRGPPGP-----QGPPGEIGFPGQPGAKGDR-GLPGRDGVAGVPGPQGTPGLI 521
Query: 340 GQPGGLNRHSDL------------SGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSA 387
GQPG + G PG A P D H L P+ P +
Sbjct: 522 GQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDG-HPGLPG--PKGSPGS 578
Query: 388 QDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP 447
GL RGPP + FPG + G PGPP A P + D A
Sbjct: 579 V-GLKGERGPPGGVG---FPG----SRGDTGPPGPPGYGPAGP---------IGDKGQAG 621
Query: 448 YPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLP-F 506
+P PG P G P P + P +++P P P G E L P F
Sbjct: 622 FPGGPGSP----------GLPGP-------KGEP---GKIVPL--PGPPGAEGLPGSPGF 659
Query: 507 PAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFG 564
P GP+ G +G GT G+ P EK + G G P +G+ PG
Sbjct: 660 P--GPQ---GDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGL--PG------- 705
Query: 565 VAQPQVSPHGTPSLPPPRVVGASPS-ESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623
+ P GTP P + +P + P G L + P P + S
Sbjct: 706 ----DMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPG--LKGLPGLPGIPGTPGEKGS 759
Query: 624 -QLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAF 682
+PG G PP G P P P P S+ + P G+G GA
Sbjct: 760 IGVPGVPGEHGAIGPPGLQGIRGEPGP-PGLPGSVGSPGVP-----------GIGPPGA- 806
Query: 683 QCLEETPFPHEGPEVGRG--GLQGFP-----RAPPPYPTHHFSLSSASLDQLDVLLTCRQ 735
GP G+G GL G P + P +P + D+ L
Sbjct: 807 ----------RGPPGGQGPPGLSGPPGIKGEKGFPGFPG--LDMPGPKGDKGAQGLPGIT 854
Query: 736 CDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAK 795
L G ++ + G +PG PG P P AP +P + H
Sbjct: 855 GQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKG----DHG- 909
Query: 796 TFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDME-------DDAKLDSLITEAL 848
G + G DP G + P +DM D + +
Sbjct: 910 ---FPGSSGPRG--DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGE 964
Query: 849 NGMEYQSDNPEIDSSFIDVFADEEPSGPRG----------PSSGHPLKSKAGV----TPE 894
G P + +P GP+G P P S G+ TP
Sbjct: 965 KGSRGDPGTPGVPGKDGQAGQPGQP-GPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPG 1023
Query: 895 SKAPPPLPAATPDPQTPRPGDRGCPAR----GRPKTRSLGLAPTEAD---APSQGRQQRR 947
K P +P P P GD+G G P GL + D A G +
Sbjct: 1024 EKGVPGIPGPQGSPGLP--GDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEK 1081
Query: 948 GKQLKLFRKDLDSGGAAEGS-GSGGGGRASGLRPRRND----GLGERPPPRPRRPRTQAP 1002
G++ + + +GS GS G + GL + D GL P + P
Sbjct: 1082 GEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP 1141
Query: 1003 GSRADPAPR-VPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061
G + P + +P LP R P A+G K
Sbjct: 1142 GPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKG-------------DKGSK 1188
Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR----GEKRKEVELTQGPREDEPQKPRKAARQ 1116
E F + P +G GF G G G T+GP+ D + +
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPG 1248
Query: 1117 EAGGDGAPANPEEPG--GSRPGPG--RSPQARGPSRSLETGAAAREGGPKCADRPSVAPK 1172
G G P P G G + PG +P GP G +G P P +
Sbjct: 1249 LPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPK-----GDPGFQGMPGIGGSPGITGS 1303
Query: 1173 DPLQVPTNTETSEETR--PSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGE--M 1228
P + + P L + + + ++ P + + L PP +
Sbjct: 1304 KGDMGPPGVPGFQGPKGLPGL----QGIKGDQGDQGVPGA----KGLPGPPGPPGPYDII 1355
Query: 1229 GASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLG--------GPGGT 1280
PGL PE PP + G P P G T G PG+ G GP G
Sbjct: 1356 KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGP 1415
Query: 1281 QAPVSHNSKDPPARQPGEFLAPVANPS 1307
P P PG + P PS
Sbjct: 1416 TGPRGFPGPPGPDGLPGS-MGPPGTPS 1441
Score = 56.2 bits (134), Expect = 6e-07
Identities = 117/468 (25%), Positives = 156/468 (33%), Gaps = 77/468 (16%)
Query: 3392 CSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRP----GAPGQKARALEGTLPSKRR 3447
C C+ K ++ +R L G + F G++ P G PGQK E LP +
Sbjct: 36 CGKCDCHGVKGQKGERG----LPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKG 91
Query: 3448 RVAMPGSA--PG-------PGEDRPP-PRGSSPILSEGSLPALLHLCSEVAPSTTKGWPE 3497
PG++ PG PG+D PP P G +P E P G P
Sbjct: 92 TRGPPGASGYPGNPGLPGIPGQDGPPGPPG---------IPGCNGTKGERGPLGPPGLPG 142
Query: 3498 TLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPG 3557
P P ++G P L P L +G+ G P PG
Sbjct: 143 FAGNPGPPGLPGMKG---------DPGEILGHVPGMLL--KGERGFPGIPGTPGPPGLPG 191
Query: 3558 SPGPLLQQALPLGASLP--RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHL 3615
GP+ P G + P PG G E + L F G + G +G P
Sbjct: 192 LQGPV----GPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQ 247
Query: 3616 LQKEKEVSSSHMVSEGGP------RGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPV 3669
+Q++ + ++ + G G KG KP KD S FP
Sbjct: 248 VQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPG--FPG 305
Query: 3670 HPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQL 3729
P PG + R G K PGP G+ G K G + P +
Sbjct: 306 EPG------YPGLIGRQGPQGEKGEA--GPPGPPGIVIGTGPLGEK---GERGYPGTPGP 354
Query: 3730 QSETATTPAKPSFPS--RSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESST 3787
+ E P FP P P LP QA P E GE+G G G G S
Sbjct: 355 RGE----PGPKGFPGLPGQPGPPGLPVPGQA-GAPGFPGERGEKGDRGFPGTSLPGPSG- 408
Query: 3788 KRKKGQVPGPARSES-VGSFGRAPSAPDKPPRTPRKQATPSRVLPTKP 3834
+ +PGP S G G + P P Q P +P +P
Sbjct: 409 ---RDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPG--IPGQP 451
Score = 51.2 bits (121), Expect = 2e-05
Identities = 211/963 (21%), Positives = 292/963 (30%), Gaps = 229/963 (23%)
Query: 1684 GDSRPPQDVCLPEPSKQPGPQLDAG-----SLAKCSPDQELSFPKNKEAASSQESED--S 1736
G PP ++ P QPG + D G +A Q + A + E
Sbjct: 480 GPQGPPGEIGFPG---QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFD 536
Query: 1737 LRLLPCEQRGGFLPEPGTADQP-------HRGAPAPEAFGSPAVHLAPDLAFQGDGAPPL 1789
LRL + GF +PG + H G P P+ GSP + +G+ PP
Sbjct: 537 LRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPK--GSPG-----SVGLKGERGPPG 589
Query: 1790 DATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASS--LTAPRGREAWL 1847
+P ++G + G G + AG G +G P G S L P+G +
Sbjct: 590 GVGFP-------GSRGDT-GPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKI 641
Query: 1848 VPVPSPACVSNT--------------------HPSRRSQDPALSPPIRQLQLPGPGVAKS 1887
VP+P P P + A+ P + PGP K
Sbjct: 642 VPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQP--GIGFPGPPGPKG 699
Query: 1888 KDGILGLQELTPAAQSPPRVNPSGLEGGT-VEGGKVACGPA-------------QGSPGG 1933
DG+ G ++ P +P R +GL G V+G K G G+PG
Sbjct: 700 VDGLPG--DMGPPG-TPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756
Query: 1934 VQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNAS 1993
+P V G + G G+ G+ G+ G+ P G
Sbjct: 757 KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGS-PGVPGIGPPGARGPPGGQGP 815
Query: 1994 PKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEG 2053
P L+GP KG + P P P + A L +SG G
Sbjct: 816 P--GLSGP-------PGIKGEKGFPGF-----PGLDMPGPKGDKGAQGLPGITGQSGLPG 861
Query: 2054 RTPERASSPGL--------NKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPRE 2105
P + +PG+ ++ T P +P P A +P G
Sbjct: 862 -LPGQQGAPGIPGFPGSKGEMGVMGTPGQPG---------SPGPVGAPGLPGEKG--DHG 909
Query: 2106 DPLTSPSRAQGGLGGQ-----LPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG 2160
P +S R GL G LP P D + G +
Sbjct: 910 FPGSSGPRGDPGLKGDKGDVGLPGKPGSMDK-------------VDMGSMKGQKGDQGEK 956
Query: 2161 AEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDS 2220
+ P+ P P G P +D + PG PK
Sbjct: 957 GQIGPIGEKGSRGDPGTP------------GVPGKDGQAGQPGQPG----------PKG- 993
Query: 2221 TLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPG-PD 2279
PG + +P G P +V GL TP +G+PG P
Sbjct: 994 ---------------DPGISGTPGAPGLPGPKGSVGGMGLPGTP------GEKGVPGIPG 1032
Query: 2280 PQSRGAPPHTNPDRMPRGHSSYSPSNTARL-GHREGQAVTAVPTEPPTLQGAG------- 2331
PQ P + +G + L G + Q + P P G
Sbjct: 1033 PQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGM 1092
Query: 2332 PDSPACLEGEMGTSSKEPEDPGTP-ETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDF 2390
P SP L+G G S P PG P E G G + + GL T P+ A
Sbjct: 1093 PGSPG-LKGSPG-SVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAG-- 1148
Query: 2391 QSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCA 2450
Q P S +G+P P RG+ P + + KG EV
Sbjct: 1149 QKGEPGSDGIPGSAGEKGEPGLP------GRGFPGFPGAKGDKGSKG---------EVGF 1193
Query: 2451 ASFRSGPGLSRHKARK-------HRPHPGAPAEPSPAAL-------PAQQP-LEPLAQKC 2495
PG+ K + + PG P P A P QP L L
Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPM 1253
Query: 2496 QPP----------RKKSHRVSGKERPNHSRGDPSHVTQP-----PPAQGSKEVLRAPGSP 2540
PP K + G +GDP P P GSK + PG P
Sbjct: 1254 GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVP 1313
Query: 2541 HSQ 2543
Q
Sbjct: 1314 GFQ 1316
Score = 47.4 bits (111), Expect = 3e-04
Identities = 115/483 (23%), Positives = 150/483 (31%), Gaps = 70/483 (14%)
Query: 3413 LRGGRQP---FAFRGVRRP-GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGS 3468
L+G R P F G R G PG G + K + PG PG P P+G
Sbjct: 581 LKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQ-AGFPGGPGSPG--LPGPKGE 637
Query: 3469 S----PILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPP 3524
P+ L P +G+P T RP LP
Sbjct: 638 PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRP-----------GLPGEKGAVGQ 686
Query: 3525 PSLS----PFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLP----RP 3576
P + P P + GD G RP PG+PG Q+ P G LP P
Sbjct: 687 PGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEP-GVGLPGLKGLP 745
Query: 3577 GARG-QDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRG 3635
G G G++ + G PG G P Q + + V G G
Sbjct: 746 GLPGIPGTPGEKGSIGVPG---VPGEHGAIGPPGLQ--GIRGEPGPPGLPGSVGSPGVPG 800
Query: 3636 TFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT 3695
G+ P G K FP P G PG G+
Sbjct: 801 IGPPGARGPPGGQGPPGLSGPPGIKGEKG--FPGFP----GLDMPGPKGDKGAQGL---- 850
Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755
PG + Q PG + G P S + + TP +P SP P P
Sbjct: 851 ----PGITGQSGLPGLPGQQGAPGIPGFPGS-KGEMGVMGTPGQPG----SPGPVGAPGL 901
Query: 3756 AQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDK 3815
P E G+ G GS GP +G+ K KG V P + S+ K
Sbjct: 902 ---------PGEKGDHGFPGSSGP--RGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQK 950
Query: 3816 PPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLR 3875
+ + Q P + K P P + + +PG K G + G P L
Sbjct: 951 GDQGEKGQIGP---IGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLP 1007
Query: 3876 PPK 3878
PK
Sbjct: 1008 GPK 1010
Score = 46.6 bits (109), Expect = 5e-04
Identities = 304/1293 (23%), Positives = 398/1293 (30%), Gaps = 274/1293 (21%)
Query: 1678 GLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKC-------SPDQELSFPKNKEA-AS 1729
GL +G PP P P PGP + G + DQ +S P A
Sbjct: 188 GLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQ 247
Query: 1730 SQESEDSLRLLPCEQRG--GFLPEPGTADQPHRGAPAPEA----------FGSPAVHLAP 1777
QE D Q+G GF PG ++ G P P GSP P
Sbjct: 248 VQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEP 307
Query: 1778 DL----------AFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGN 1827
+G+ PP G P G G +P G PG G
Sbjct: 308 GYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGP--------LGEKGERGYP--GTPGPRG- 356
Query: 1828 EFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQ-------DPALSPPIRQLQLP 1880
E P G L G +PVP A P R + +L P + LP
Sbjct: 357 EPGPKGFPGLPGQPGPPG--LPVPGQAGAPG-FPGERGEKGDRGFPGTSLPGPSGRDGLP 413
Query: 1881 G-------PGVAKSKDGILGLQELTPAAQSPP----------RVNPSGLEGGT-----VE 1918
G PG +GI+ Q P Q PP + G +G + ++
Sbjct: 414 GPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDID 473
Query: 1919 GGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEA----------DGHWGLLGQAEKTQGQG 1968
G + GP QG PG + P G + GL G GL+GQ G
Sbjct: 474 GYRGPPGP-QGPPGEIGFPGQPGAKGDR-GLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531
Query: 1969 --------TANQLQPENGVSPGGTDNHASVNASPKTALTGP--TEGAVLLEKCKGSRAAM 2018
++ P PG T S L GP + G+V L+ +G +
Sbjct: 532 EFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGV 591
Query: 2019 SLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRT--PERASSPGLNKPLLATGDSPA 2076
T PP P A + G +G+ P SPGL P G
Sbjct: 592 GFPGSRGDT-GPPGPPGYGPAGPI-------GDKGQAGFPGGPGSPGLPGPKGEPGK--- 640
Query: 2077 PSVGDLAACAPSPTSAAHMPCSLG-PLPREDPLTSPSRAQGGLGGQLPA----SPSCRDP 2131
P P A +P S G P P+ D + + GL G+ A P
Sbjct: 641 ------IVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGP 694
Query: 2132 PGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAP--------PSLTTSPCDPKEALA 2183
PGP+ + DG+ D G +P P P + +P L
Sbjct: 695 PGPKGV-------------DGLPG--DMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLP 739
Query: 2184 GCLLQG-------EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWES 2236
G L+G G+P E S PG V H P I + L S
Sbjct: 740 G--LKGLPGLPGIPGTPGEKGSIGVPG----VPGEHGAIGP-PGLQGIRGEPGPPGLPGS 792
Query: 2237 PGRATSPPLA--GAVSPSVAVRATGLSSTP-----TGDEAQAGRGLPGP--DPQSRGAPP 2287
G P + GA P GLS P G G +PGP D ++G P
Sbjct: 793 VGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG 852
Query: 2288 HTNPDRMP-RGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSS 2346
T +P +P G + V P +P + GP L GE G
Sbjct: 853 ITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGS---PGPVGAPGLPGEKG--- 906
Query: 2347 KEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSD--SPQSHRNASHQ 2404
D G P G SG P + +GL P S + D S + + +
Sbjct: 907 ----DHGFP--GSSGPRGDPGLKGDKGDVGL-----PGKPGSMDKVDMGSMKGQKGDQGE 955
Query: 2405 TPQGDPLGPQDLKQRSRGYKKKPA----STENGQWKGQAPHG-PVTCEVCAASFRSGP-- 2457
Q P+G ++ SRG P + GQ P G P A GP
Sbjct: 956 KGQIGPIG----EKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKG 1011
Query: 2458 ---GLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHS 2514
G+ + PG P LP + + + PP + G++
Sbjct: 1012 SVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGI 1071
Query: 2515 RGDPSHVTQPPPAQGSKEVLRAPGSPHSQQL--------HPPSP--TEHEVDVKTPASKP 2564
G P P +G K + PG P S L +P SP + D P
Sbjct: 1072 AGFPG----SPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDG 1127
Query: 2565 RPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVS 2624
P E L P + EP D S G+ + RG P
Sbjct: 1128 IPGVKGEAGL-PGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRG--------FPGF 1178
Query: 2625 ADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQ----PPRLATLGPGVMEGAAE 2680
D +GS+ A SP G P + GEQ PP GP G
Sbjct: 1179 PGAKGD-KGSKGEVGFPGLAGSP-------GIPGSKGEQGFMGPP-----GPQGQPGLPG 1225
Query: 2681 TDQEAL--CAGETGAQKPPGDRMLCPGRMDGAALG--EQPTGQKG----ASARGFWGPRE 2732
+ A G+ G Q PG L PG M L + G KG A G GP+
Sbjct: 1226 SPGHATEGPKGDRGPQGQPGLPGL-PGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKG 1284
Query: 2733 TKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPP-----LGPLGFPETSSSPADSTTS 2787
G P S+ + PP GP G P D
Sbjct: 1285 DPGFQGMPGIGGSPGITGSKG----------DMGPPGVPGFQGPKGLPGLQGIKGDQGDQ 1334
Query: 2788 SC--LQGLPDNPDTQG---------GVQGPEGP 2809
+GLP P G G+ GPEGP
Sbjct: 1335 GVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP 1367
Score = 43.5 bits (101), Expect = 0.004
Identities = 123/511 (24%), Positives = 156/511 (30%), Gaps = 110/511 (21%)
Query: 1068 SESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANP 1127
++ E PP PGF G G + P E P + E G G P P
Sbjct: 128 TKGERGPLGPPGLPGFAGNPGPPGLPG---MKGDPGEILGHVPGMLLKGERGFPGIPGTP 184
Query: 1128 EEPG-----GSRPGPGRSPQARGPSRSLETGAAAREG----GPKCADRPSVAPKDPLQVP 1178
PG G PG + P G + G GPK D+ P VP
Sbjct: 185 GPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPK-GDKGDQGVSGPPGVP 243
Query: 1179 TNTETSEETRPSLDFPQEAKEPETAE---ESAPDSTEFTEALRSPPAACAGEMGAS---- 1231
+ E+ DF + ++ + E + P E E + P G+ G
Sbjct: 244 GQAQVQEKG----DFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKG 299
Query: 1232 ----------PGLLIPEQPPPSRHDTGTPKPSGSLANTAP---HGSSPTPGVGSLLGGPG 1278
PGL+ + P + + G P P G + T P G PG G PG
Sbjct: 300 SPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPG 359
Query: 1279 GTQAPVSHNSKDPPARQ-PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLG 1337
P PP PG+ AP P K GF L
Sbjct: 360 PKGFPGLPGQPGPPGLPVPGQAGAP---------GFPGERGEK------GDRGFPGTSLP 404
Query: 1338 VPVAKKG-PQPYSSPHSELFLGPKDLAGCF--LEELHPKPSARDAPPA------------ 1382
P + G P P SP GP G + E P P PP
Sbjct: 405 GPSGRDGLPGPPGSP------GPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIG 458
Query: 1383 -----SSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFD 1437
SCL D + G P P+ PPG PG+ P DR
Sbjct: 459 EKGQKGESCLICDID--GYRGPPGPQGPPGEIGF-PGQ-------------PGAKGDRGL 502
Query: 1438 PPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLS 1497
P G G P P K P + + L ++ P P P ++G
Sbjct: 503 PGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQ-PGMTG----- 556
Query: 1498 KTCPPERTVVPG--AAPSLPG-KGSGCSVAL 1525
R PG P LPG KGS SV L
Sbjct: 557 ------RAGSPGRDGHPGLPGPKGSPGSVGL 581
Score = 42.4 bits (98), Expect = 0.009
Identities = 73/293 (24%), Positives = 95/293 (32%), Gaps = 49/293 (16%)
Query: 509 GGPEWQG--GSQGALGTAGKTPGPREKLPAVRSSQG--------GSPALFTYNGMTDPGA 558
G P QG G QG G G T P LP + ++G G+P L G P
Sbjct: 61 GFPGMQGPEGPQGPPGQKGDTGEPG--LPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPG 118
Query: 559 QPLFFGV--AQPQVSPHGTPSLP-------PPRVVG--ASPSESPLPSPATNTAGSTCSS 607
P G + + P G P LP PP + G P E P G
Sbjct: 119 PPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFP 178
Query: 608 LSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAK 667
P + P L GP+GP F PP P G P P E + P+ K
Sbjct: 179 GIPGTPGPPGLPG----LQGPVGPPGFTGPPGPP---GPPGPPGEKGQMGLSFQGPKGDK 231
Query: 668 AFPFPADGLGAEGAFQCLEETPFPHEGP--EVGRGGLQGFP----RAPPPYPTHHFSLSS 721
+ G G Q E+ F +G + G G QG P + P P
Sbjct: 232 GDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPG- 290
Query: 722 ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLP 774
+ D+ F + GL+ + G + GPPG P
Sbjct: 291 ------------KDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPP 331
Score = 37.7 bits (86), Expect = 0.23
Identities = 85/349 (24%), Positives = 111/349 (31%), Gaps = 30/349 (8%)
Query: 3531 PAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARGQDAEGKRAP 3589
P RGD G + PG PGP + P PG +G G P
Sbjct: 961 PIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKG-SVGGMGLP 1019
Query: 3590 LVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649
G++ PG G D + EK + + G RG G
Sbjct: 1020 GT-PGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSP 1078
Query: 3650 SSSKDRSAASTPSKALKFPVHP--RKAVGSLA-PGELARGTENGMKPATP-KAKPGPSSQ 3705
++ + P P P + + GS+ PG E G K PG +
Sbjct: 1079 GEKGEKGSIGIPG----MPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGE 1134
Query: 3706 GSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765
PG G + +P S + +A +P P R P AK
Sbjct: 1135 AGLPGTPGPTGPAGQKGEPGSDGIPG-SAGEKGEPGLPGRG-----FPGFPGAKGDKGSK 1188
Query: 3766 REAGEQGPHGSLG-PKEKGESSTKRKKGQVPGPARSESV-GSFGRAPSAPDKPPRTPRKQ 3823
E G G GS G P KGE PGP + GS G A P K R P+ Q
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGP----PGPQGQPGLPGSPGHATEGP-KGDRGPQGQ 1243
Query: 3824 ATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
LP P P P P + K + G+ G P+G P
Sbjct: 1244 PG----LPGLPGP--MGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDP 1286
Score = 37.0 bits (84), Expect = 0.39
Identities = 119/525 (22%), Positives = 156/525 (29%), Gaps = 119/525 (22%)
Query: 3428 PGAPGQKA----RALEGT-LPSKRRRVAMPGSA-------------------PGPGEDRP 3463
PG PG++ R GT LP R +PG PGP D+
Sbjct: 384 PGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQG 443
Query: 3464 PPR--GSSPILSE-------GSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCE 3514
PP G + E G + + P +G P + P P RG
Sbjct: 444 PPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLP 503
Query: 3515 LPSNHQECPPPSLSP----------------FPAALADGRGDCA------LDGALERPEN 3552
P P +P F L +GD + G P
Sbjct: 504 GRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGR 563
Query: 3553 EASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQE 3612
+ PG PGP PG+ G +G+R P G PG+RG P
Sbjct: 564 DGHPGLPGP-----------KGSPGSVG--LKGERGP---PGGVGFPGSRGDTGP----- 602
Query: 3613 DHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPR 3672
GP G KG A P G S P K + P P
Sbjct: 603 ----------PGPPGYGPAGPIG--DKGQAGFPGGPGSPGLP-GPKGEPGKIVPLPGPPG 649
Query: 3673 KAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSE 3732
+PG + G P TP +PG + +PG G P+ G L +
Sbjct: 650 AEGLPGSPGFPGPQGDRGF-PGTP-GRPGLPGEKGAVGQPGIGFPGPPGPKGVDG-LPGD 706
Query: 3733 TAT--TPAKPSFPSRSPAP----------ERLPARAQAKSCTKGPREAGEQ--------- 3771
TP +P F P LP P GE+
Sbjct: 707 MGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVP 766
Query: 3772 GPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPP--RTPRKQATPSRV 3829
G HG++GP G + + G P S G G P PP + P + P +
Sbjct: 767 GEHGAIGP--PGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGI 824
Query: 3830 LPTKPKPNSQNKPRPPPSEQRKAE--PGHTQRKDRLGKAFPQGRP 3872
K P P P + A+ PG T + G QG P
Sbjct: 825 KGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAP 869
Score = 35.8 bits (81), Expect = 0.86
Identities = 46/186 (24%), Positives = 59/186 (31%), Gaps = 17/186 (9%)
Query: 1237 PEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPG--GTQAPVSHNSKDPPAR 1294
P+ PP + DTG P G+ P G+S PG L G PG G P +
Sbjct: 71 PQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKG 130
Query: 1295 QPGEFLAPVANPSSTACPKPSVLSSKISS----FGCDPAGFNRDPLGVPVAKKGPQPYSS 1350
+ G L P P P P L G P + G P P P
Sbjct: 131 ERGP-LGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGL 189
Query: 1351 PHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGE----DAGSLEPQLPRSPP 1406
P + +GP G P P PP + + D G P P
Sbjct: 190 PGLQGPVGPPGFTG------PPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVP 243
Query: 1407 GTAETE 1412
G A+ +
Sbjct: 244 GQAQVQ 249
Score = 33.5 bits (75), Expect = 4.3
Identities = 50/203 (24%), Positives = 67/203 (33%), Gaps = 36/203 (17%)
Query: 3686 GTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFP-- 3743
GT+ P P PG + PG K G G L P P P
Sbjct: 127 GTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGP 186
Query: 3744 ---------------SRSPAPERLPA----RAQAKSCTKGPREAGEQGPHGSLGP----- 3779
+ P P P + Q +GP+ G++G G GP
Sbjct: 187 PGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPK--GDKGDQGVSGPPGVPG 244
Query: 3780 ----KEKGESSTKRKKGQ--VPGPARSESVGSFGR--APSAPDKPPRTPRKQATPSRVLP 3831
+EKG+ +TK +KGQ PG VG G P KP + K S P
Sbjct: 245 QAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFP 304
Query: 3832 TKPKPNSQNKPRPPPSEQRKAEP 3854
+P + P E+ +A P
Sbjct: 305 GEPGYPGLIGRQGPQGEKGEAGP 327
Score = 32.3 bits (72), Expect = 9.5
Identities = 57/220 (25%), Positives = 73/220 (33%), Gaps = 45/220 (20%)
Query: 2325 PTLQGA-GPDSPACLEGEMGTSSKEPEDPGTPET-GRSGATKMPRVTCPSTGLGLGRTTA 2382
P +QG GP P +G+ G EP PGT T G GA+ P G
Sbjct: 63 PGMQGPEGPQGPPGQKGDTG----EPGLPGTKGTRGPPGASGYP-----------GNPGL 107
Query: 2383 PSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHG 2442
P D P + + PLGP L G+ P KG G
Sbjct: 108 PGIPGQD-GPPGPPGIPGCNGTKGERGPLGPPGLP----GFAGNPGPPGLPGMKGDP--G 160
Query: 2443 PVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPA-QQPLEPLA--------Q 2493
+ V PG+ + R PG P P P LP Q P+ P
Sbjct: 161 EILGHV--------PGML---LKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPG 209
Query: 2494 KCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEV 2533
PP +K + P +GD V+ PP G +V
Sbjct: 210 PPGPPGEKGQMGLSFQGPKGDKGDQG-VSGPPGVPGQAQV 248
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 102 bits (253), Expect = 1e-20
Identities = 312/1322 (23%), Positives = 413/1322 (31%), Gaps = 280/1322 (21%)
Query: 28 GHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQ------ 81
G P P L P T T G + G LP + + G PP L G
Sbjct: 337 GPPGPPGLVIPRPGTGITIGEK---GNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393
Query: 82 ---APSSTPGKRGSP--QTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDE- 135
P PG+RG + PPG S + P L G+ G+P G A P+ DE
Sbjct: 394 GPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQP-GAPGLPGPPGPAGPHIPPS-DEI 450
Query: 136 ----------TPENPQLEAAQLPEVDTPQ------GPG-TGAPLRPGLPRTEAQPAAEEL 178
+P + L+ Q + D G G +G P +PGLP P + L
Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS--L 508
Query: 179 GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPA 238
GF E + + P P APG P S+G +PG + D
Sbjct: 509 GFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG----EPGDILTFPGMKGDK---- 560
Query: 239 AENSFPGANFGVP--PAEP--EPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAG 294
E PGA G+P P P + +P P G P G++F+ G P + G
Sbjct: 561 GELGSPGAP-GLPGLPGTPGQDGLPGLPGPKGEPGGITFK-------GERGPPGNPGLPG 612
Query: 295 HAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGA 354
GP+ P G P VG + P +P +G PG G
Sbjct: 613 LPGNIGPM-----GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667
Query: 355 LSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRAS 414
+PG P L P +P G+ ++G P +P PG
Sbjct: 668 PGNPGRDGDVGLPGDPGL--------PGQP--GLPGIPGSKGEPG-IPGIGLPGPP-GPK 715
Query: 415 GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPS-PGQR 473
G PGPP APG P R+ P +P P G P A G P PG +
Sbjct: 716 GFPGIPGPP----GAPGTP-GRIGLEGPPGPPGFPGPKGEPGFALPGP--PGPPGLPGFK 768
Query: 474 LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAG--GPEWQGGSQGALGTAG----KT 527
L +P P P G L LP P G GP Q G G G G
Sbjct: 769 GALGPKGDRGFP-----GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823
Query: 528 PGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVG-- 585
PGP G+ P QP G+ + P G P L P G
Sbjct: 824 PGPP--------------------GIPGPIGQPGLHGIPGEKGDP-GPPGLDVPGPPGER 862
Query: 586 ASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETG 645
SP P P + P S + S PG G PP P G
Sbjct: 863 GSPGIPGAPGP-----------IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911
Query: 646 SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGF 705
P S P Q +P P P G++G L P P + +G G +G
Sbjct: 912 IPGRSGVPGLKGDDGLQGQPG--LPGPTGEKGSKGE-PGLPGPPGPMDPNLLGSKGEKGE 968
Query: 706 PRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQ 765
P P + + + GL + G
Sbjct: 969 PGLP--------------------------------GIPGVSGPKGYQGLPGDPGQPGLS 996
Query: 766 RSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGD---AQAEGKDDPLRTGFLPSLAA 822
PG PG P P P +P GL+ GD +G + P +P
Sbjct: 997 GQPGLPGPPGPKGNPGLP--GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054
Query: 823 TPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSG 882
+P LP D + D + S+ L G + + P + G +G S G
Sbjct: 1055 SP-GLPGQKGD-KGDPGISSIGLPGLPGPKGEPGLPGYPGN----------PGIKG-SVG 1101
Query: 883 HPLKSKAGVTPESKAPPPLPA--ATPDPQTPR-----PGDRGCPARGRPKTRSLGLAPTE 935
P TP +K P LP TP P P+ PG+ G P G P G P +
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP--GEPGPVGGGGHPGQ 1159
Query: 936 ADAPSQ----------GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGL------- 978
P + G ++G+ + + G SG G G G+
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219
Query: 979 RPRRNDGLG-----ERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPR 1033
P+ G + PP P P G + +P P+ P P + + LP
Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGP-----PGRPGPTGFQGLPGP 1274
Query: 1034 KDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKR 1093
+ P GG G E+ P PG G +G
Sbjct: 1275 EGPPGLPGNGGIKG-----------------------EKGNPGQPGLPGLPGLKG----- 1306
Query: 1094 KEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETG 1153
QGP + R G G P P PG GP P + GP
Sbjct: 1307 -----DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG--MKGPSGVPGSAGP------- 1352
Query: 1154 AAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEF 1213
EG P + P P +P + S + P +P P +
Sbjct: 1353 ----EGEPGL-----IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1403
Query: 1214 TEALRSPPA----------ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHG 1263
PP AG PGL P Q P +R G P P G P G
Sbjct: 1404 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL--PGQ-PGTRGLDGPPGPDGLQGPPGPPG 1460
Query: 1264 SS 1265
+S
Sbjct: 1461 TS 1462
Score = 86.3 bits (212), Expect = 6e-16
Identities = 325/1384 (23%), Positives = 425/1384 (30%), Gaps = 260/1384 (18%)
Query: 2 PGERPR----GAP-PPTMTGDLQPRQVASSPGHPSQP--PLEDNTPATRTTKGAREAGGQ 54
PG R + G P PP G P + PG P P P D P + G G+
Sbjct: 71 PGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130
Query: 55 AQAMELPEAQPRQARDGELKPPSLRGQAPS----STPGKRGSP--QTPPGRSPLQAPSRL 108
P Q G P ++G+ S S PG +G+P PPG L P+ +
Sbjct: 131 RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGI 190
Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168
G P G+ P L N L Q P+ + + G P PG
Sbjct: 191 PGPIGPPGPP----GLMGPPGPPGLPGPKGNMGLNF-QGPKGEKGEQGLQGPPGPPGQIS 245
Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPA----PGPPQSRGTSPLQPGSY 224
+ +P E F + Q P P PP PGPP + G
Sbjct: 246 EQKRPIDVE--FQKGDQGLPGD---------RGPPGPPGIRGPPGPPGGEKGEKGEQGEP 294
Query: 225 PEYQASGADSWPPAAENSFPGANFGVP-----PAEP-------------EPIPKG---SR 263
+ G D EN PG G+P P EP P P G R
Sbjct: 295 GKRGKPGKDG-----ENGQPGIP-GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPR 348
Query: 264 PG-GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQG--AWPEEAVGT 320
PG G G P L G + + G GP A P G +P E
Sbjct: 349 PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQK 408
Query: 321 GPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKIL 380
G P P P P P GQPG G PG A
Sbjct: 409 GDEGP-PGISIPGP-PGLDGQPGA-------PGLPGPPGPAG------------------ 441
Query: 381 PERPPSAQDGLGSTRGPPSSLPQRHFPG-QAYRASGVDTSPGPPDTELAAPGPPPARLPQ 439
P PPS + GPP S + G Q + DT T ++ P P LP
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPG-LPG 500
Query: 440 LWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGME 499
L P PPG L GQ LP P P ++ P +
Sbjct: 501 L--------PGPPGS-LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI- 550
Query: 500 MLSRLPFPA-GGPEWQGGSQGALGTAGK--TPGPREKLPAVRSSQGGSPALFTYNGMTDP 556
L FP G + + GS GA G G TPG ++ LP + +G P T+ G P
Sbjct: 551 ----LTFPGMKGDKGELGSPGAPGLPGLPGTPG-QDGLPGLPGPKG-EPGGITFKGERGP 604
Query: 557 GAQPLFFGVAQPQVSPHGTPSLPPPRVVG--------ASPSESPLPSPATNTAGSTCSSL 608
P G+ + P G P PP VG +P + +P P + +
Sbjct: 605 PGNPGLPGLPG-NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPG 663
Query: 609 SPMSSSPANPSSE-ESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAK 667
P P NP + + LPG G P P G P P LP P+
Sbjct: 664 KP--GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP---GIPGIGLPGPPGPKGFP 718
Query: 668 AFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQL 727
P P G G LE P P P G G GF PP P
Sbjct: 719 GIPGPPGAPGTPGRIG-LEGPPGPPGFP--GPKGEPGFALPGPPGPP------------- 762
Query: 728 DVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAH 787
L F A G + PGPPG P +P
Sbjct: 763 --------------GLPGFKG---------ALGPKGDRGFPGPPGPPGRTGLDGLPGPK- 798
Query: 788 AGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITE- 846
GD G+ P+ LP + P P + I +
Sbjct: 799 -------------GDVGPNGQPGPMGPPGLPGIGVQGPPGPPG---------IPGPIGQP 836
Query: 847 ALNGMEYQSDNPEIDSSFIDVFADEEPS-------GPRGPSSGHPLKSKAGVT--PESKA 897
L+G+ + +P + E S GP GP L KAG + P +K
Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896
Query: 898 PPPLPAATPDPQTPR--PGDRGCPA-------RGRPKTRSLGLAPTEADAPSQGRQQRRG 948
+ P P P PG G P +G+P GL + S+G G
Sbjct: 897 EMGM-MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP-----GLPGPTGEKGSKGEPGLPG 950
Query: 949 KQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERP--PPRPRRPRTQAP-GSR 1005
+ L S G G G SG P+ GL P P +P P G +
Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIPGVSG--PKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008
Query: 1006 ADPA-PRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREY 1064
+P P P P + P + G G+ + QK +
Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068
Query: 1065 DFASESEEDEQPPPRG-------------------PGFRGRRGRGEKRKEVELTQGPRED 1105
+S P P+G PG G G + + L P
Sbjct: 1069 GISSIGLPG-LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP 1127
Query: 1106 EPQKPRKAARQEAGGDGAPANPEEPG----GSRPGPGRSPQARG-PSRSLETGAAAREGG 1160
P P+ + G G P P EPG G PG P +G P + G A ++G
Sbjct: 1128 GPPGPKGIS----GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE 1183
Query: 1161 PKCADRPSVAPKDPLQVP-TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRS 1219
P +P P +P + + + P + P P E +
Sbjct: 1184 P---GQPGFGNPGPPGLPGLSGQKGDGGLPGI--PGNPGLPGPKGEPGFHGFPGVQGPPG 1238
Query: 1220 PPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGG 1279
PP + + G P+ PP G P P+G P G PG G + G G
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPP------GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGN 1292
Query: 1280 TQAP 1283
P
Sbjct: 1293 PGQP 1296
Score = 82.8 bits (203), Expect = 6e-15
Identities = 173/692 (25%), Positives = 218/692 (31%), Gaps = 157/692 (22%)
Query: 1 MPGERPRGAPP----PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQ 56
+PGE+ PP P G+ + +PG P PP P G G+
Sbjct: 841 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMG 899
Query: 57 AMELPEAQPRQARDGELKPPSLRGQ----------APSSTPGKRGSPQTPPGRSPLQAPS 106
M P G P L+G P+ G +G P P P+ P+
Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-PN 958
Query: 107 RLAGRAE-GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG 165
L + E G P I G++ + L P P L P + P GP G P PG
Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ--PGLPGPPGP-KGNPGLPG 1015
Query: 166 LPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSY- 224
P P + + + P PP P + SP PG
Sbjct: 1016 QPGLIGPPGLK------------GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKG 1063
Query: 225 ----PEYQASGADSWP-PAAENSFPG--ANFGVPPAEPEPIPKGSRPG--GSPRGVSFQF 275
P + G P P E PG N G+ + +P PG G+P G Q
Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP----GLPGLPGTP-GAKGQP 1118
Query: 276 PFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPL 335
P G P P ++G G P P VG G P QP P
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPG-------LPGEPGP---VGGGGH---PGQPGP--- 1162
Query: 336 PCYQGQPG--GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGS 393
P +G+PG G+ + G PG + P + LP P GL
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP--GNPGLPG 1220
Query: 394 TRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPG 453
+G P FPG GPP GPP + P L P P P P
Sbjct: 1221 PKGEPGF---HGFPGVQ----------GPP-------GPPGSPGPALEGPKGNPGPQGPP 1260
Query: 454 GPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP-- 511
G RP P G + LP P G P
Sbjct: 1261 G-------------------------------------RPGPTGFQ---GLPGPEGPPGL 1280
Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQG-----GSPALFTYNGMT-DPG--AQPLFF 563
GG +G G G+ P LP ++ QG G+P NGM DPG P F
Sbjct: 1281 PGNGGIKGEKGNPGQPGLP--GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP 1338
Query: 564 GVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623
G+ P P P ++G P LP P S S + A P
Sbjct: 1339 GMKGPSGVPGSAGPEGEPGLIG-PPGPPGLPGP---------SGQSIIIKGDAGPPGIPG 1388
Query: 624 Q-----LPGPLGPSAF---FHPPTHPQETGSP 647
Q LPGP GP PP P G P
Sbjct: 1389 QPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1420
Score = 62.8 bits (151), Expect = 7e-09
Identities = 315/1316 (23%), Positives = 396/1316 (30%), Gaps = 210/1316 (15%)
Query: 309 PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGA-AHSAP 365
P+G ++ + GP P + P LP + G PG G+ H G PG
Sbjct: 73 PRGQKGDDGI-PGPPGPKGIRGPPG-LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130
Query: 366 RPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT 425
R F S P P GL GPP + PG +S PGP
Sbjct: 131 RGFPGS---------PGFP-----GLQGPPGPPGIPGMKGEPGSIIMSS----LPGPKGN 172
Query: 426 ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLP-------- 477
PGPP + L PT P P P GP G P P + L
Sbjct: 173 P-GYPGPPG--IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229
Query: 478 -----QSAPLPWPQVLPTARP----------------SPHGMEMLSRLPFPAGGPEWQGG 516
Q P P Q+ RP P G + P P GG + + G
Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289
Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPG--AQPLFFGVAQPQVSPHG 574
QG G GK PG + + G P + G DPG +P G + Q G
Sbjct: 290 EQGEPGKRGK-PG--------KDGENGQPGIPGLPG--DPGYPGEPGRDG-EKGQKGDTG 337
Query: 575 TPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634
P PP +V +P P T G T + E PG GP
Sbjct: 338 PPG--PPGLV--------IPRPGT---GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL 384
Query: 635 FHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEG 694
PP G P P P + P + P P GL + L P P G
Sbjct: 385 PGPP-GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLDGQPGAPGLPGPPGP-AG 441
Query: 695 PEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQLDVLLTCRQC-------DRNYSSLAAF 746
P + P P PP L + D TC C L
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501
Query: 747 LAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPA-DAHAGLLSHAKTFL-LAGDAQ 804
G + + G + GP GLP P AP P G TF + GD
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561
Query: 805 AEGKDDPLRTGFLPSLAATPFP--LPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDS 862
G P G LP L TP LP + + G NP +
Sbjct: 562 ELG--SPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGI------TFKGERGPPGNPGLPG 612
Query: 863 SFIDVFADEEPS-GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDP-----QTPRPGDR 916
++ P GP GP ++ AG + P +P DP Q +PG
Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAG----NPGQPGIPGPKGDPGQTITQPGKPGLP 668
Query: 917 GCPAR----GRPKTRSLGLAPTEADAP-SQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971
G P R G P L P P S+G G L G G+ G
Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728
Query: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRL 1030
GL E PP P P + PG P P R
Sbjct: 729 TPGRIGL---------EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779
Query: 1031 PPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRG 1090
P P R G G + + Q + + PP PG G+ G
Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839
Query: 1091 EKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL 1150
E P D P P R G GAP P P GS PG++ + P
Sbjct: 840 GIPGEKGDPGPPGLDVPGPP--GERGSPGIPGAP-GPIGPPGSPGLPGKAGASGFPGTKG 896
Query: 1151 ETGAAAREGG------PKCADRPSVAPKDPLQ----VPTNT-ETSEETRPSLDFPQEAKE 1199
E G G P + P + D LQ +P T E + P L P +
Sbjct: 897 EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956
Query: 1200 P-------ETAEESAP-----DSTEFTEALRSPPAACAGEMGAS--PGLLIPEQP----- 1240
P E E P + + L P G+ G S PGL P P
Sbjct: 957 PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP----GQPGLSGQPGLPGPPGPKGNPG 1012
Query: 1241 -PPSRHDTGTPKPSGSLAN---TAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQ- 1295
P G P G++ + P G PG + G PG P K P
Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072
Query: 1296 ---PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPH 1352
PG P P P + + DP G P G P AK P P
Sbjct: 1073 IGLPG-LPGPKGEPGLPGYPGNPGIKGSVG----DP-GLPGLP-GTPGAKGQPGLPGFPG 1125
Query: 1353 SELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETE 1412
+ GPK ++G PP + + G G P P PPG + +
Sbjct: 1126 TPGPPGPKGISG---------------PPGNPGLPGEPGPVGGGGHPGQP-GPPG-EKGK 1168
Query: 1413 PGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANR-DSGLPFACADPPQKTVPSDPPYP 1471
PG+ P PP LS + D GLP +P +P +
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228
Query: 1472 SFLLLEEVSPMLPSHFPDLSGGK-VLSKTCPPER--------TVVPGAAPSLPGKG 1518
F ++ S P L G K PP R P P LPG G
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNG 1284
Score = 57.0 bits (136), Expect = 4e-07
Identities = 116/457 (25%), Positives = 139/457 (30%), Gaps = 77/457 (16%)
Query: 20 PRQVASSPGHPSQPPLEDNT--PATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPS 77
P+ PG+P P ++ + P G A GQ P G PP
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP---------GTPGPPG 1131
Query: 78 LRG-QAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDET 136
+G P PG G P G P + G P Q I G A + +P
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK--GKPGQDGIPGPAGQKGEPG---Q 1186
Query: 137 PENPQLEAAQLPEVDTPQGPG--TGAPLRPGLPRTEAQPAAEELGFHRC--FQEPPSSFT 192
P LP + +G G G P PGLP + +P GFH Q PP
Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP-----GFHGFPGVQGPPG--- 1238
Query: 193 STNYTSPSATPRPPAPGPPQSRGTS--PLQPGSYPEYQASGADSWPPAAENSFPGANFGV 250
P +P P GP + G P +PG G + P N G
Sbjct: 1239 ------PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGN 1292
Query: 251 PPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQ 310
P P G + P G+ P L+G P V G GP P
Sbjct: 1293 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV----PG 1348
Query: 311 GAWPEEAVGT-GPAYPLPTQPAPSPLPCY---QGQPGGLNRHSDLSGALSSPGAAHSAPR 366
A PE G GP P P P PS P G+ L G L P P
Sbjct: 1349 SAGPEGEPGLIGPPGP-PGLPGPSGQSIIIKGDAGPPGIPGQPGLKG-LPGPQGPQGLPG 1406
Query: 367 PFSDSLHKSLTKILPERPPSAQ-----DGLGSTRGPPSSLPQRHFPGQAYRAS------- 414
P P P DG G +G P PGQ
Sbjct: 1407 PTG-----------PPGDPGRNGLPGFDGAGGRKGDPG------LPGQPGTRGLDGPPGP 1449
Query: 415 -GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT 450
G+ PGPP T A G R Q D P T
Sbjct: 1450 DGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1486
Score = 52.0 bits (123), Expect = 1e-05
Identities = 117/458 (25%), Positives = 144/458 (31%), Gaps = 74/458 (16%)
Query: 3425 VRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLC 3484
+ +PG PG L G P + V +PG PG+ P G E +P +
Sbjct: 659 ITQPGKPG-----LPGN-PGRDGDVGLPGDPGLPGQPGLP--GIPGSKGEPGIPGI---- 706
Query: 3485 SEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALD 3544
P KG+P P P T G E P P P P AL G L
Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP-GFALPGPPGPPGLP 765
Query: 3545 G---ALERPENEASPGSPGPLLQQALPLGASLPRP----GARGQDAEGKRAPLVFSGKRR 3597
G AL + PG PGP + L LP P G GQ L G +
Sbjct: 766 GFKGALGPKGDRGFPGPPGPPGRTGLD---GLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822
Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSA 3657
PG G P H + EK + GP G +GS P
Sbjct: 823 PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG--ERGSPGIPG----------- 869
Query: 3658 ASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717
A P P P KA S PG T+ M P PGP S PG K
Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPG-----TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924
Query: 3718 GGSQPQPA-------SGQLQSETATTPAKPSFPS--------RSPAPERLPARAQAKSCT 3762
G Q QP G P P P+ P +P + K
Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984
Query: 3763 KGPREAGEQGPHGSLG----PKEKGESSTKRKKGQVPGPARSESVGSFG-RAPSAPDKPP 3817
P + G+ G G G P KG + G + P ++G G P + PP
Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044
Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855
PS V P P P + K +PG
Sbjct: 1045 -------GPSGV------PGQPGSPGLPGQKGDKGDPG 1069
Score = 51.6 bits (122), Expect = 2e-05
Identities = 170/687 (24%), Positives = 226/687 (32%), Gaps = 102/687 (14%)
Query: 871 EEPSGPRGPSSGHPLKSKAGVTPES-KAPPPLPAATPDPQTP-RPGDRGCPA-RGRPKTR 927
E P GPRG + G P+ + PP LP P P PG G P +G P
Sbjct: 68 EGPPGPRGQKGDDGIPGPPG--PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIP--- 122
Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR-PRRNDGL 986
G T+ + G G Q G G G S L P+ N G
Sbjct: 123 --GCNGTKGERGFPGSPGFPGLQ-----GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY 175
Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046
P + T PG P P P + + P+ K G
Sbjct: 176 PGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235
Query: 1047 GKELILKIVQQKNRLREYDFASESE--EDEQPPPRGPGFRGRRG--RGEKRKEVELTQGP 1102
G + ++ R + +F + ++ PP PG RG G GEK ++ E
Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----- 290
Query: 1103 REDEPQKPRKAARQ-EAGGDGAPANPEEPGGSRPG-PGRSPQARGPSRSLETGAAAREG- 1159
+ EP K K + E G G P P +PG PG PGR + + +TG G
Sbjct: 291 -QGEPGKRGKPGKDGENGQPGIPGLPGDPG--YPGEPGRDGE---KGQKGDTGPPGPPGL 344
Query: 1160 -GPKCADRPSVAPKDPLQVP-TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217
P+ ++ K + +P E E P + P P A P
Sbjct: 345 VIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG------- 397
Query: 1218 RSPPAACAGEMG-----ASPGLLIPEQP-----PPSRHDTGTPKPSG-------SLANTA 1260
P GE G PG+ IP P P + G P P+G +
Sbjct: 398 ---PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454
Query: 1261 PHGSSPTPGVGSLLGGPG--GTQAPVSHN----SKDPPARQPGEFLAPVANPSSTACPKP 1314
P G +PG L G G G + N P QPG P P S P
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP-GPPGSLGFPGQ 513
Query: 1315 SVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL-FLGPKDLAGCFLEELHPK 1373
+ + G P G P G P A P P L F G K G EL
Sbjct: 514 KGEKGQAGATG--PKGLPGIP-GAPGAPGFPGSKGEPGDILTFPGMKGDKG----EL-GS 565
Query: 1374 PSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPG--TAETEPGRAASPPTLESSSLFPDL 1431
P A P + G+D P P+ PG T + E G +P P L
Sbjct: 566 PGAPGLPGLPGT----PGQDGLPGLPG-PKGEPGGITFKGERGPPGNPG-------LPGL 613
Query: 1432 P--VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD 1489
P + PP +G + G+ +P Q +P P + + P LP + P
Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN-PG 672
Query: 1490 LSGGKVLSKTCPPERTVVPGAAPSLPG 1516
G L P +PG P LPG
Sbjct: 673 RDGDVGL-----PGDPGLPG-QPGLPG 693
Score = 47.8 bits (112), Expect = 2e-04
Identities = 113/463 (24%), Positives = 147/463 (31%), Gaps = 74/463 (15%)
Query: 3432 GQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPST 3491
G K E P +PG PGP E P PRG + +P P
Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGF-PGP-EGPPGPRGQK---GDDGIPGPPGPKGIRGPPG 96
Query: 3492 TKGWPETLERPV------DPVTHPIRGCELPSNHQECPP----PSLS--PFPAALADGRG 3539
G+P T P P I GC + P P L P P + +G
Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156
Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-------------RPGARGQDAEGK 3586
+ P + +PG PGP Q LP +P PG G
Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216
Query: 3587 RAPLVFSGKRRAPGARGRCAP-----DHFQEDHLLQKEKEVSSSHMVSEGGPRG-TFHKG 3640
L F G + G +G P ++ + E + + + GP G +G
Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276
Query: 3641 SATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA-----PGELARGTENGMKPAT 3695
P G + ++ K K + + + L PGE R E G K T
Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT 336
Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755
PGP G PRPGT G + L E + FP P LP
Sbjct: 337 --GPPGP--PGLVIPRPGTGITIGEKGNIGLPGLPGE----KGERGFPG-IQGPPGLP-- 385
Query: 3756 AQAKSCTKGPREAGEQGPHGSLG-PKEKGESSTKRKKG-QVPGPARSESVGSFGRAPSAP 3813
GP A GP G G P E+G+ + G +PGP + P AP
Sbjct: 386 --------GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG------QPGAP 431
Query: 3814 DKP-PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855
P P P P +P P P PP S K G
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGP-----PGPPGSPGDKGLQG 469
Score = 47.8 bits (112), Expect = 2e-04
Identities = 95/368 (25%), Positives = 119/368 (32%), Gaps = 95/368 (25%)
Query: 3427 RPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPR-GSSPILSEGSLPALLHLCS 3485
+PG PG+K + + +P + PG PG G PP G S +G LP +
Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQ-PGFGNPGPPGLPGLSGQKGDGGLPGI----- 1212
Query: 3486 EVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDG 3545
G P +P H G + P P P SP PA L+G
Sbjct: 1213 -------PGNPGLPGPKGEPGFHGFPGVQGP------PGPPGSPGPA----------LEG 1249
Query: 3546 ALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA-EGKRAPLVFSGKRRAPGARGR 3604
P + PG PGP Q LP G P PG G +G++ G PG +G
Sbjct: 1250 PKGNPGPQGPPGRPGPTGFQGLP-GPEGP-PGLPGNGGIKGEKGNPGQPGLPGLPGLKG- 1306
Query: 3605 CAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKA 3664
+ GP G +G+ +P G D P
Sbjct: 1307 -------------------------DQGPPGL--QGNPGRP-GLNGMKGDPGLPGVPG-- 1336
Query: 3665 LKFP--VHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQ-----GSGSP-----RP 3712
FP P GS P G + P P PGPS Q G P +P
Sbjct: 1337 --FPGMKGPSGVPGSAGP----EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQP 1390
Query: 3713 GTKTGGGSQ-PQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ 3771
G K G Q PQ G P+ P P LP A P G+
Sbjct: 1391 GLKGLPGPQGPQGLPG------------PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1438
Query: 3772 GPHGSLGP 3779
G G GP
Sbjct: 1439 GTRGLDGP 1446
Score = 44.7 bits (104), Expect = 0.002
Identities = 115/475 (24%), Positives = 140/475 (29%), Gaps = 62/475 (13%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG PG + LP PG GE PP P L L +
Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN-----------PGLPGLPGNI 617
Query: 3488 APSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546
P G+ P PV I+G P P P G+ L G
Sbjct: 618 GPMGPPGF-----GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP--GLPGN 670
Query: 3547 LERPENEASPGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF---SGKRRAPGAR 3602
R + PG PG Q LP + S PG G G P F G APG
Sbjct: 671 PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730
Query: 3603 GRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS 3662
GR + K + GP G A P G DR P
Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPG 784
Query: 3663 ----------KALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP 3712
K V P G + P L G P P PGP Q P
Sbjct: 785 PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG--PPGPPGIPGPIGQPGLHGIP 842
Query: 3713 GTKTGGGSQPQPASGQL-QSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ 3771
G K G G + + P P P P LP +A A E G
Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMM 901
Query: 3772 GPHGSLGPKE----------KGESSTKRKKGQVPGPARSESVGSFGR----APSAPDKPP 3817
GP G GP KG+ + + G +PGP + GS G P P P
Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEK--GSKGEPGLPGPPGPMDPN 958
Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
K LP P + + P + +PG + + G P+G P
Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLPGPPGPKGNP 1011
Score = 43.9 bits (102), Expect = 0.003
Identities = 117/515 (22%), Positives = 162/515 (31%), Gaps = 75/515 (14%)
Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLP 3478
P ++G+ PG PGQ + + LP PG PG PP G + + P
Sbjct: 980 PKGYQGL--PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP--GLKGTIGDMGFP 1035
Query: 3479 ALLHLCSEVAPSTTKGWPETLERPV------DPVTHPIRGCELPSNHQECPPPSLSPFPA 3532
+ PS G P + P DP I LP E P L +P
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE---PGLPGYP- 1091
Query: 3533 ALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAE------- 3584
G+ + G++ P PG+PG Q LP P P G +G
Sbjct: 1092 ------GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145
Query: 3585 GKRAPLV---FSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRG----TF 3637
G+ P+ G+ PG +G+ D +K GP G +
Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP---AGQKGEPGQPGFGNPGPPGLPGLSG 1202
Query: 3638 HKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPK 3697
KG P + P GS PG G + P P
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS--PGPALEGPKGNPGPQGPP 1260
Query: 3698 AKPGPSS-QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFP--------SRSPA 3748
+PGP+ QG P G P +G ++ E P +P P P
Sbjct: 1261 GRPGPTGFQGLPGPE-------GPPGLPGNGGIKGEKG-NPGQPGLPGLPGLKGDQGPPG 1312
Query: 3749 PERLPARAQAKSCTKGPREAGEQGPHGSLGPK-EKGESSTKRKKGQV--------PGPA- 3798
+ P R P G G G GP G + + + G + PGP+
Sbjct: 1313 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1372
Query: 3799 RSESVGSFGRAPSAPDKP--PRTPRKQATPSRVLPTKP--KPNSQNKPRPPPSEQRKAEP 3854
+S + P P +P P Q PT P P P + RK +P
Sbjct: 1373 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1432
Query: 3855 GHTQRKDRLGKAFPQGRPLLR----PPKRGTAVHG 3885
G + G P G L+ PP + HG
Sbjct: 1433 GLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHG 1467
Score = 43.5 bits (101), Expect = 0.004
Identities = 199/866 (22%), Positives = 253/866 (29%), Gaps = 161/866 (18%)
Query: 1752 PGTADQPHR-GAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGR 1810
PG QP G P P P + + ++ G PP G+ QG +
Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-------GSPGDKGLQGEQGVK 474
Query: 1811 A----------GGHLHPTAGRPGFEGNEFAPA-----------GASSLTAPRGREAWLVP 1849
G + G+PG G P G + T P+G L
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG----LPG 530
Query: 1850 VPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNP 1909
+P P + P L PG K + G G L +P +
Sbjct: 531 IPGA-------PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583
Query: 1910 SGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGT 1969
GL G E G + +G PG + LP G +G G G +G EK
Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG-PMGPPGFGPPGPVG--EKGIQGVA 640
Query: 1970 ANQLQPENGVSPGGTDNHASVNASPKTALTG--PTEGAVLLEKCKGSRAAMSLQ----EE 2023
N QP G+ D ++ K L G +G V L G L +
Sbjct: 641 GNPGQP--GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698
Query: 2024 AEP------TPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077
EP P PP P G+ G TP R GL P G P P
Sbjct: 699 GEPGIPGIGLPGPPGPK------GFPGIPGPPGAPG-TPGRI---GLEGPPGPPG-FPGP 747
Query: 2078 SVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137
G+ P P +P G L P +G G PPGP
Sbjct: 748 K-GEPGFALPGPPGPPGLPGFKGAL-------GPKGDRGFPG-----------PPGP--- 785
Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDP 2197
P L+ G + + P+ PP L G +QG P P
Sbjct: 786 ----PGRTGLDGLPGPKGDVGPNGQPGPMGPP-----------GLPGIGVQGPPGPPGIP 830
Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257
P G P L +P PG SP + GA P +
Sbjct: 831 G--PIGQPGLHGIPGEKGDPGPPGLDVP---------GPPGERGSPGIPGAPGPIGPPGS 879
Query: 2258 TGL-----SSTPTGDEAQAG-RGLPGPD-----PQSRGAPPHTNPDRMPRGHSSYSPSNT 2306
GL +S G + + G G PGP P G P D + P+
Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939
Query: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKE-----PEDPGTPETGRSG 2361
G P +P L G L G G S + P DPG P G SG
Sbjct: 940 KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP--GLSG 997
Query: 2362 ATKMPRVTCPSTGLGL----GRTTAP--SSTASDFQSDSPQSHRNASHQTPQGDPLGP-Q 2414
+P P GL G P T D PQ P G P P
Sbjct: 998 QPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP--PGPSGVPGQPGS 1055
Query: 2415 DLKQRSRGYKKKPASTENGQWKGQAPHG-------PVTCEVCAASFRSG-PGLSRHKARK 2466
+G K P + G P G P + + G PGL K
Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115
Query: 2467 HRP----HPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVT 2522
+P PG P P P + L + P H G+ P +G P
Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH--PGQPGPPGEKGKPGQDG 1173
Query: 2523 QPPPAQGSKEVLRAPGSPHSQQLHPP 2548
P PA E PG P PP
Sbjct: 1174 IPGPAGQKGE----PGQPGFGNPGPP 1195
Score = 42.4 bits (98), Expect = 0.009
Identities = 276/1195 (23%), Positives = 359/1195 (30%), Gaps = 236/1195 (19%)
Query: 1684 GDSRPPQD-VCLPEPSKQPGPQLDAGSLAK---CSPDQELSFPKNKEAASSQESEDSLRL 1739
G PP D +C P P PG D G + + F S + L
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500
Query: 1740 LPCEQRGGFLPEPG-TADQPHRGAPAPEAFGSPAVHLAPDL-AFQGDGAPPLDATWPFGA 1797
LP G L PG ++ GA P+ G P + AP F G P D F
Sbjct: 501 LPGPP--GSLGFPGQKGEKGQAGATGPK--GLPGIPGAPGAPGFPGSKGEPGDIL-TFPG 555
Query: 1798 SPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLV------PVP 1851
+ S G G G PG G + G L P+G + P
Sbjct: 556 MKGDKGELGSPGAPG-----LPGLPGTPGQD----GLPGLPGPKGEPGGITFKGERGPPG 606
Query: 1852 SPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGL--QELTPAAQSPP---- 1905
+P P + PP PGP K G+ G Q P + P
Sbjct: 607 NPGL-----PGLPGNIGPMGPP--GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659
Query: 1906 -RVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQ----LGLEA-DGHWGLLG 1959
+ GL G G V G PG + +P G +GL G G G
Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719
Query: 1960 QAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMS 2019
GT ++ E P G P AL GP L G + A+
Sbjct: 720 IPGPPGAPGTPGRIGLE---GPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGALG 772
Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSV 2079
+ + P PP P + L G G+ P PGL P + P P
Sbjct: 773 PKGD-RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGL--PGIGVQGPPGPP- 827
Query: 2080 GDLAACAPSPTSAAH-MPCSLG-PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137
P H +P G P P + P +G G +P +P PPG
Sbjct: 828 ---GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG--IPGAPGPIGPPG---- 878
Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDP 2197
SP A G T P PP P + + G L+G+ P
Sbjct: 879 ---SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP--GRSGVPG--LKGDDGLQGQP 931
Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257
P T + + L P L S G P L G S
Sbjct: 932 GLPGP--------TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGY 983
Query: 2258 TGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAV 2317
GL P GLPGP P +G P P +G
Sbjct: 984 QGLPGDPGQPGLSGQPGLPGP-PGPKGNPG--------------LPGQPGLIG------- 1021
Query: 2318 TAVPTEPPTLQGA----GPDSPACLEGEMGTSS--KEPEDPGTPETGRSGATKMPRVTCP 2371
PP L+G G P +EG G S +P PG P G+ G P +
Sbjct: 1022 ------PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP--GQKGDKGDPGI--- 1070
Query: 2372 STGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTE 2431
+ +GL P + P N + GDP P G P +
Sbjct: 1071 -SSIGLPGLPGPKG-----EPGLPGYPGNPGIKGSVGDPGLP--------GLPGTPGA-- 1114
Query: 2432 NGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRP-HPGAPAEPSPAALPAQQPLEP 2490
KGQ P P F PG K P +PG P EP P P +P
Sbjct: 1115 ----KGQ-PGLP--------GFPGTPGPPGPKGISGPPGNPGLPGEPGPVG-GGGHPGQP 1160
Query: 2491 LAQKCQPPRKK----SHRVSGKERPNHSRGDPSHVTQPPPA----QGSKEVLRAPGSPHS 2542
PP +K + G G P PP G K PG P +
Sbjct: 1161 -----GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGN 1215
Query: 2543 QQLHPP--SPTEHEV-DVKTPASKP-RPDQAREDELHPKQAEKREGRRWRREPT----VD 2594
L P P H V+ P P P A E PK +G R PT +
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG---PKGNPGPQGPPGRPGPTGFQGLP 1272
Query: 2595 SPSHSEGKSNKKRGKLRGRRLRE-ESILPVSADVISDGRGSRPSPAMASYAASPSHCLSV 2653
P G G ++G + + LP + +G + P + P +
Sbjct: 1273 GPEGPPGLPG--NGGIKGEKGNPGQPGLPGLPGL----KGDQGPPGLQGNPGRPG-LNGM 1325
Query: 2654 EGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALG 2713
+G P G P GP + G+A + GE G PPG L PG + +
Sbjct: 1326 KGDPGLPG-VPGFPGMKGPSGVPGSAGPE------GEPGLIGPPGPPGL-PGPSGQSIII 1377
Query: 2714 EQPTGQKG----ASARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEGVWEENTPPL 2769
+ G G +G GP+ + L P
Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQGL-----------------------------PGPT 1408
Query: 2770 GPLGFPETSSSPADSTTSSCL--QGLPDNPDTQG--------GVQGPEGPTPDAS 2814
GP G P + P GLP P T+G G+QGP GP +S
Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1463
Score = 40.4 bits (93), Expect = 0.035
Identities = 56/209 (26%), Positives = 69/209 (33%), Gaps = 18/209 (8%)
Query: 3693 PATPKAKPGPSSQGSG---SPRPGTKTGGGSQPQPASGQLQSETATT----PAKPSFPSR 3745
P P PG + S PG K G P L T P P
Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204
Query: 3746 SPAPERLPA-RAQAKSCTKGPR-EAGEQGPHGSLGP-----KEKGESSTKRKKGQ--VPG 3796
P P LP + +GP+ E GEQG G GP ++K + +KG +PG
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264
Query: 3797 PARSESVGSFGRAPSAPDKPPRTPRKQATPS-RVLPTKPKPNSQ-NKPRPPPSEQRKAEP 3854
P P +Q P R P K N Q P P EP
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324
Query: 3855 GHTQRKDRLGKAFPQGRPLLRPPKRGTAV 3883
G K + G P G P L P+ GT +
Sbjct: 325 GRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353
Score = 37.7 bits (86), Expect = 0.23
Identities = 50/197 (25%), Positives = 62/197 (31%), Gaps = 35/197 (17%)
Query: 489 PTARPSPHGMEMLSRLPFPAG-----GPEWQGGSQGALGTAGK-----TPGPREKLPAVR 538
P P P G + +P P G GP G G G G PGP + +P
Sbjct: 67 PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP-QGIPGCN 125
Query: 539 SSQG-----GSPALFTYNGMTDPGAQPLFFG-----VAQPQVSPHGTPSLPPPRVVGASP 588
++G GSP G P P G + P G P P P + P
Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP 185
Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSA--FFHPPTHPQETGS 646
+ +P P P P P LPGP G F P E G
Sbjct: 186 GPTGIPGPIGPPG-------PPGLMGPPGPPG----LPGPKGNMGLNFQGPKGEKGEQGL 234
Query: 647 PFPSPEPPHSLPTHYQP 663
P P PP + +P
Sbjct: 235 QGP-PGPPGQISEQKRP 250
Score = 37.0 bits (84), Expect = 0.39
Identities = 169/712 (23%), Positives = 217/712 (30%), Gaps = 136/712 (19%)
Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASA 3265
P P+ G R G PG P + PG P P + DGA P
Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH-DGAPGPQGIPG 123
Query: 3266 T--ALADAGSPGPP-----RTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCG--- 3315
+ G PG P + P P P GEP + + + P + + G
Sbjct: 124 CNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKGNPGYPGPPG 180
Query: 3316 -KRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLY 3374
+ P P + + P + P P + G + + G G LQ P
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240
Query: 3375 ACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGAP--G 3432
++ I + F K +Q L G R P G+R P P G
Sbjct: 241 PGQISEQKRPI----------DVEFQKGDQ-------GLPGDRGPPGPPGIRGPPGPPGG 283
Query: 3433 QKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTT 3492
+K E P KR + PG+D E P +
Sbjct: 284 EKGEKGEQGEPGKRGK---------PGKD-----------GENGQPGI------------ 311
Query: 3493 KGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA--LADGRGDCALDGAL--- 3547
G P P +P +G + PP + P P +G+ L G
Sbjct: 312 PGLPGDPGYPGEPGRDGEKG-QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370
Query: 3548 -ER--PENEASPGSPGPLLQQALPLGASLPR--PGARGQDAEGKRAPLVFS-----GKRR 3597
ER P + PG PGP A +G P PG RGQ +G P S G
Sbjct: 371 GERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQ--KGDEGPPGISIPGPPGLDG 426
Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR-- 3655
PGA G P H + S + E GP G G Q D+
Sbjct: 427 QPGAPGLPGPPGPAGPH-------IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479
Query: 3656 -------SAASTPSKALKFPVHPRKAVGSLA----PGELARGTENGMK--PATPKAKPGP 3702
+ S P P P GSL GE + G K P P A P
Sbjct: 480 TCFNCIGTGISGPPGQPGLPGLPGPP-GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538
Query: 3703 SSQGS-GSPR-----PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756
GS G P PG K G P + L T P + P P P+ P
Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGL-PGPKGEPGGI 596
Query: 3757 QAKSCTKGPR----------EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSF 3806
K +GP G GP G P GE + G P G
Sbjct: 597 TFKG-ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655
Query: 3807 GRAPSAPDKP--PRTPRKQATPSRVLPTKP-KPNSQNKPRPPPSEQRKAEPG 3855
G+ + P KP P P + LP P P P P S K EPG
Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVG--LPGDPGLPGQPGLPGIPGS---KGEPG 702
Score = 36.2 bits (82), Expect = 0.66
Identities = 105/488 (21%), Positives = 148/488 (30%), Gaps = 82/488 (16%)
Query: 2101 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLAC-----------------SPA 2143
P P+ P + ++ + G G P P + PPGP + +P
Sbjct: 116 PGPQGIPGCNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPG 174
Query: 2144 WAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP----KEALAGCLLQG-EGSPLEDPS 2198
+ G+ T P PP L P P + G QG +G E
Sbjct: 175 YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGL 234
Query: 2199 SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRAT 2258
PPG ++ + + + + L G P + G P +
Sbjct: 235 QGPPGPPGQIS-------EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287
Query: 2259 GLSSTPTGDEAQAGR----------GLPGPDPQSRGAPPH---------TNPDRMPRGHS 2299
G + G+ GLPG DP G P T P P G
Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPP-GLV 345
Query: 2300 SYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDP-GTP-ET 2357
P +G + + +P E G P L G G + P P G P E
Sbjct: 346 IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405
Query: 2358 GRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLK 2417
G+ G P ++ P G+ AP + H S + + P GP
Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGP---HIPPSDEICEPGPPGPPG-- 460
Query: 2418 QRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGP----GLSRHKARKHRPHPGA 2473
S G K KG TC C + SGP GL PG
Sbjct: 461 --SPGDKGLQGEQGVKGDKGD------TCFNCIGTGISGPPGQPGL-----------PGL 501
Query: 2474 PAEPSPAALPAQQPLEPLAQKCQPPRKKS-HRVSGKERPNHSRGDPSHVTQPPPAQGSKE 2532
P P P Q+ + A P G S+G+P + P +G K
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561
Query: 2533 VLRAPGSP 2540
L +PG+P
Sbjct: 562 ELGSPGAP 569
Score = 34.3 bits (77), Expect = 2.5
Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 16/133 (12%)
Query: 3183 LGDLPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240
L LPG G +G + + P PK G G PG G + PG
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164
Query: 3241 ERAKPRARSTPS--------NPDGAATPDSASATALA----DAGSPGPPRT--TPSPSPD 3286
E+ KP P G P L+ D G PG P P P +
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224
Query: 3287 PWAGGEPLLQATP 3299
P G P +Q P
Sbjct: 1225 PGFHGFPGVQGPP 1237
Score = 33.9 bits (76), Expect = 3.3
Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 16/121 (13%)
Query: 3186 LPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAKKDS 3238
LPG GL G + + + P P+ G G PG P G +G+ S
Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072
Query: 3239 PGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQAT 3298
G P + P P P ++ D G PG P T P A G+P L
Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKG--SVGDPGLPGLPGT-------PGAKGQPGLPGF 1123
Query: 3299 P 3299
P
Sbjct: 1124 P 1124
Score = 33.1 bits (74), Expect = 5.6
Identities = 22/55 (40%), Positives = 22/55 (40%), Gaps = 3/55 (5%)
Query: 1232 PGLLIPEQPPPSRH---DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283
PG PE PP R D G P P G P G PG L G PG AP
Sbjct: 62 PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 101 bits (252), Expect = 1e-20
Identities = 326/1413 (23%), Positives = 429/1413 (30%), Gaps = 239/1413 (16%)
Query: 1 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60
+PG P G P P G P + PG P P + N +G + G+ Q ++
Sbjct: 184 LPG--PTGIPGPI--GPPGPPGLMGPPGPPGLPGPKGNMGLN--FQGPKGEKGE-QGLQG 236
Query: 61 PEAQPRQARDGELKPPSLRGQ-APSSTPGKRGSPQTPPGRSPLQAPSRLAGRA--EGSPP 117
P P Q + + +P + Q PG RG P P R P P G +G P
Sbjct: 237 PPGPPGQISE-QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295
Query: 118 QRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGL--PRTEAQPAA 175
+R G +P + P +P + + Q TG P PGL PR
Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355
Query: 176 EELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSW 235
E G P P P PGPP + P P +P + D
Sbjct: 356 GEKGN---IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEG 412
Query: 236 PPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGH 295
PP P G P A P P G P G S + P G P + G
Sbjct: 413 PPGISIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470
Query: 296 AFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-----LPTQPAPSPLPCYQGQPG------- 343
G +G +GTG + P LP P P + GQ G
Sbjct: 471 QGVKG--------DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522
Query: 344 -GLNRHSDLSGALSSPGAAHSAPRP-----------FSDSLHKSLTKILPERPPS-AQDG 390
G + GA +PG S P L LP P + QDG
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582
Query: 391 LGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT--ELAAPGPPPARLP---------- 438
L GP F G+ G +PG P + GPP P
Sbjct: 583 LPGLPGPKGEPGGITFKGE----RGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQG 638
Query: 439 QLWDPTAAPYPTPPGGP---LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP------ 489
+P P P G P + G P + LP LP LP
Sbjct: 639 VAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698
Query: 490 -------TARPSPHGMEMLSRLPFPAGGPEWQG--GSQGALGTAGKTPGPREKLPAVRSS 540
P P G + +P P G P G G +G G G PGP+ +
Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG-FPGPKGEPGFALPG 757
Query: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQP--------------QVSPHGTPS-LPPPRVVG 585
G P L + G P F G P V P+G P + PP + G
Sbjct: 758 PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817
Query: 586 ----ASPSESPLPSPATNTA-----GSTCSSLSPMSSSPANPSSEESQ----LPGPLGPS 632
P +P P G P P P S PGP+GP
Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877
Query: 633 AFFHPPTHPQETG-SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691
P P + G S FP + + P P + G +G + P
Sbjct: 878 G---SPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934
Query: 692 HEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQ 751
E G G G P PP P L S + + + +
Sbjct: 935 GPTGEKGSKGEPGLP--GPPGPMDPNLLGSKG----------EKGEPGLPGIPGVSGPKG 982
Query: 752 FCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGD---AQAEGK 808
+ GL + G PG PG P P P +P GL+ GD +G
Sbjct: 983 YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP--GQPGLIGPPGLKGTIGDMGFPGPQGV 1040
Query: 809 DDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVF 868
+ P +P +P LP D + D + S+ L G + + P +
Sbjct: 1041 EGPPGPSGVPGQPGSP-GLPGQKGD-KGDPGISSIGLPGLPGPKGEPGLPGYPGN----- 1093
Query: 869 ADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPA--ATPDPQTPR-----PGDRGCPAR 921
G +G S G P TP +K P LP TP P P+ PG+ G P
Sbjct: 1094 -----PGIKG-SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP-- 1145
Query: 922 GRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPR 981
G P G P + P G + + G+ G G+ G GL +
Sbjct: 1146 GEPGPVGGGGHPGQPGPP--GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203
Query: 982 RNDGLGERPPPRPRRPRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRK 1040
+ DG P P P + PG P + P PP
Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG---------------PP-------- 1240
Query: 1041 ARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQ 1100
G+ G L + Q PP PGF+G G +
Sbjct: 1241 ---GSPGPAL---------------EGPKGNPGPQGPPGRPGFQGLPG----------PE 1272
Query: 1101 GPREDEPQKPRKAA-RQEAGGDGAPANPEEPG--GSRPGPGRSPQARGPSRSLETGAAAR 1157
GP P P + E G G P P PG G + PG P R G
Sbjct: 1273 GP----PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ---GNPGRPGLNGMKGD 1325
Query: 1158 EGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217
G P P + K P VP + E P L P P P
Sbjct: 1326 PGLPGVPGFPGM--KGPSGVPGS--AGPEGEPGLIGP-----PGPPGLPGPSGQSIIIKG 1376
Query: 1218 RSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGP 1277
+ P G+ G GL P+ P G P P+G + +G G G G P
Sbjct: 1377 DAGPPGIPGQPGLK-GLPGPQGP------QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1429
Query: 1278 GGTQAPVSHNSKDPPARQPGEFLAPVANPSSTA 1310
G P + PP P P P +++
Sbjct: 1430 GLPGQPGTRGLDGPPG--PDGLQGPPGPPGTSS 1460
Score = 70.9 bits (172), Expect = 2e-11
Identities = 372/1580 (23%), Positives = 470/1580 (29%), Gaps = 321/1580 (20%)
Query: 2 PGERPR----GAP-PPTMTGDLQPRQVASSPGHPSQP--PLEDNTPATRTTKGAREAGGQ 54
PG R + G P PP G P + PG P P P D P + G G+
Sbjct: 71 PGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130
Query: 55 AQAMELPEAQPRQARDGELKPPSLRGQAPS----STPGKRGSP--QTPPGRSPLQAPSRL 108
P Q G P ++G+ S S PG +G+P PPG L P+ +
Sbjct: 131 RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGI 190
Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168
G P G+ P L N L Q P+ + + G P PG
Sbjct: 191 PGPIGPPGPP----GLMGPPGPPGLPGPKGNMGLNF-QGPKGEKGEQGLQGPPGPPGQIS 245
Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228
+ +P E F + Q P R P PGPP RG PG
Sbjct: 246 EQKRPIDVE--FQKGDQGLPGD-------------RGP-PGPPGIRGP----PG------ 279
Query: 229 ASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF 288
PP E G G P +P G G P G+ P G +
Sbjct: 280 -------PPGGEKGEKGEQ-GEPGKRGKPGKDGEN--GQP-GIPGLPGDPGYPGEPGRDG 328
Query: 289 PADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348
G GP +P G LP + P QG PG
Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG----- 383
Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS--AQDGLGSTRGPPSSLPQRHF 406
L G PGAA P PP + G GPP
Sbjct: 384 --LPGP---PGAAVMGP----------------PGPPGFPGERGQKGDEGPPGI----SI 418
Query: 407 PGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG 466
PG G+D PG P PGPP P + P PPG P +
Sbjct: 419 PGPP----GLDGQPGAP----GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGE 470
Query: 467 QPSPGQR--LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTA 524
Q G + C + T P G L LP P G + G +G G A
Sbjct: 471 QGVKGDKGDTCF---------NCIGTGISGPPGQPGLPGLPGPPGSLGFPG-QKGEKGQA 520
Query: 525 GKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVA--QPQVSPHGTPSLPPPR 582
G T GP+ LP + + G +P G +PG F G+ + ++ G P LP
Sbjct: 521 GAT-GPKG-LPGIPGAPG-APGFPGSKG--EPGDILTFPGMKGDKGELGSPGAPGLPGLP 575
Query: 583 VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPG---PLGPSAFFHPPT 639
LP P G T +P P LPG P+GP F P
Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG-----LPGNIGPMGPPGFGPPGP 630
Query: 640 -----------HPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEET 688
+P + G P P +P ++ +P P +G G +
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG-LPGNPGRDGDVGLPGDPGLPGQP 689
Query: 689 PFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLA 748
P G G+ G PP P +
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP------------------------- 724
Query: 749 HRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGK 808
G + G + PGPPG P P P F L G G
Sbjct: 725 -----GAPGTPGRIGLEGPPGPPGFPGPKGEPG---------------FALPGPPGPPGL 764
Query: 809 DDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVF 868
P G L FP P LD L P+
Sbjct: 765 --PGFKGALGPKGDRGFPGPPGP---PGRTGLDGL------------PGPK--------- 798
Query: 869 ADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPA-RGRPKTR 927
D P+G GP G P GV PP P P P +PG G P +G P
Sbjct: 799 GDVGPNGQPGPM-GPPGLPGIGVQG-----PPGPPGIPGP-IGQPGLHGIPGEKGDPGPP 851
Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLG 987
L + + S G G G G G ASG P +G
Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPI-----------GPPGSPGLPGKAGASGF-PGTKGEMG 899
Query: 988 ERPPPRPRRP-----RTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042
PP P P R+ PG + D + LP T + P P
Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDG--LQGQPGLPGPTGEKGSKGEPGLPGPP----- 952
Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGP 1102
G L+ S+ E+ E P PG G +G QG
Sbjct: 953 -GPMDPNLL---------------GSKGEKGEPGLPGIPGVSGPKGY----------QGL 986
Query: 1103 REDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLE-TGAAAREGGP 1161
D Q G G NP PG +PG P +G + G EG P
Sbjct: 987 PGDPGQPGLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044
Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLD------FPQEAKEPETAEESAPDSTEFTE 1215
PS P P + ++ P + P EP P +
Sbjct: 1045 G----PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP--GYPGNPGIKG 1098
Query: 1216 ALRSPPA-ACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLL 1274
++ P G GA +P P GTP P G + P G+ PG +
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPKGISGPPGNPGLPGEPGPV 1151
Query: 1275 GGPG--GTQAPVSHNSK------DPPARQPGEFLAP-VANPSSTACPKPSVLSSKISSFG 1325
GG G G P K PA Q GE P NP P LS + G
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPG---LSGQKGDGG 1208
Query: 1326 CDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSS 1385
G +P G+P K P + P + GP G LE P + PP
Sbjct: 1209 L--PGIPGNP-GLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ-GPPGRPG 1264
Query: 1386 CLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASP-----PTLESSSLFPDLPVDRFDPPL 1440
G + P LP + G + E G P P L+ P L + P L
Sbjct: 1265 FQGLPGPEG---PPGLPGN--GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1319
Query: 1441 YGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEE--VSPMLPSHFPDLSGGKVLSK 1498
G D GLP P K PS P + E + P P P SG ++ K
Sbjct: 1320 NG---MKGDPGLPGVPGFPGMKG-PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1375
Query: 1499 --TCPPERTVVPGAAPSLPG 1516
PP PG LPG
Sbjct: 1376 GDAGPPGIPGQPG-LKGLPG 1394
Score = 64.3 bits (155), Expect = 2e-09
Identities = 315/1313 (23%), Positives = 396/1313 (30%), Gaps = 207/1313 (15%)
Query: 309 PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGA-AHSAP 365
P+G ++ + GP P + P LP + G PG G+ H G PG
Sbjct: 73 PRGQKGDDGI-PGPPGPKGIRGPPG-LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130
Query: 366 RPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT 425
R F S P P GL GPP + PG +S PGP
Sbjct: 131 RGFPGS---------PGFP-----GLQGPPGPPGIPGMKGEPGSIIMSS----LPGPKGN 172
Query: 426 ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLP-------- 477
PGPP + L PT P P P GP G P P + L
Sbjct: 173 P-GYPGPPG--IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229
Query: 478 -----QSAPLPWPQVLPTARP----------------SPHGMEMLSRLPFPAGGPEWQGG 516
Q P P Q+ RP P G + P P GG + + G
Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289
Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPG--AQPLFFGVAQPQVSPHG 574
QG G GK PG + + G P + G DPG +P G + Q G
Sbjct: 290 EQGEPGKRGK-PG--------KDGENGQPGIPGLPG--DPGYPGEPGRDG-EKGQKGDTG 337
Query: 575 TPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634
P PP +V +P P T G T + E PG GP
Sbjct: 338 PPG--PPGLV--------IPRPGT---GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL 384
Query: 635 FHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEG 694
PP G P P P + P + P P GL + L P P G
Sbjct: 385 PGPP-GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLDGQPGAPGLPGPPGP-AG 441
Query: 695 PEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQLDVLLTCRQC-------DRNYSSLAAF 746
P + P P PP L + D TC C L
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL 501
Query: 747 LAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPA-DAHAGLLSHAKTFL-LAGDAQ 804
G + + G + GP GLP P AP P G TF + GD
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561
Query: 805 AEGKDDPLRTGFLPSLAATPFP--LPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDS 862
G P G LP L TP LP + + G NP +
Sbjct: 562 ELG--SPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGI------TFKGERGPPGNPGLPG 612
Query: 863 SFIDVFADEEPS-GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDP-----QTPRPGDR 916
++ P GP GP ++ AG + P +P DP Q +PG
Sbjct: 613 LPGNIGPMGPPGFGPPGPVGEKGIQGVAG----NPGQPGIPGPKGDPGQTITQPGKPGLP 668
Query: 917 GCPAR----GRPKTRSLGLAPTEADAP-SQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971
G P R G P L P P S+G G L G G+ G
Sbjct: 669 GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728
Query: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRL 1030
GL E PP P P + PG P P R
Sbjct: 729 TPGRIGL---------EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779
Query: 1031 PPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRG 1090
P P R G G + + Q + + PP PG G+ G
Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839
Query: 1091 EKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL 1150
E P D P P R G GAP P P GS PG++ + P
Sbjct: 840 GIPGEKGDPGPPGLDVPGPP--GERGSPGIPGAP-GPIGPPGSPGLPGKAGASGFPGTKG 896
Query: 1151 ETGAAAREGG------PKCADRPSVAPKDPLQ----VPTNT-ETSEETRPSLDFPQEAKE 1199
E G G P + P + D LQ +P T E + P L P +
Sbjct: 897 EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956
Query: 1200 P-------ETAEESAP-----DSTEFTEALRSPPAACAGEMGAS--PGLLIPEQP----- 1240
P E E P + + L P G+ G S PGL P P
Sbjct: 957 PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP----GQPGLSGQPGLPGPPGPKGNPG 1012
Query: 1241 -PPSRHDTGTPKPSGSLAN---TAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQ- 1295
P G P G++ + P G PG + G PG P K P
Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072
Query: 1296 ---PGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPH 1352
PG P P P + + DP G P G P AK P P
Sbjct: 1073 IGLPG-LPGPKGEPGLPGYPGNPGIKGSVG----DP-GLPGLP-GTPGAKGQPGLPGFPG 1125
Query: 1353 SELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETE 1412
+ GPK ++G PP + + G G P P PPG + +
Sbjct: 1126 TPGPPGPKGISG---------------PPGNPGLPGEPGPVGGGGHPGQP-GPPG-EKGK 1168
Query: 1413 PGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANR-DSGLPFACADPPQKTVPSDPPYP 1471
PG+ P PP LS + D GLP +P +P +
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228
Query: 1472 SFLLLEEVSPMLPSHFPDLSGGK-VLSKTCPPERTVV-----PGAAPSLPGKG 1518
F ++ S P L G K PP R P P LPG G
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNG 1281
Score = 59.3 bits (142), Expect = 7e-08
Identities = 120/461 (26%), Positives = 144/461 (31%), Gaps = 88/461 (19%)
Query: 20 PRQVASSPGHPSQPPLEDNT--PATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPS 77
P+ PG+P P ++ + P G A GQ P G PP
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP---------GTPGPPG 1131
Query: 78 LRG-QAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDET 136
+G P PG G P G P + G P Q I G A + +P
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK--GKPGQDGIPGPAGQKGEPG---Q 1186
Query: 137 PENPQLEAAQLPEVDTPQGPG--TGAPLRPGLPRTEAQPAAEELGFHRC--FQEPPSSFT 192
P LP + +G G G P PGLP + +P GFH Q PP
Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP-----GFHGFPGVQGPPG--- 1238
Query: 193 STNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVP- 251
P +P P GP + G P P P +Q PP PG N G+
Sbjct: 1239 ------PPGSPGPALEGPKGNPG--PQGPPGRPGFQGLPGPEGPPG----LPG-NGGIKG 1285
Query: 252 ----PAEPE-PIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAF 306
P +P P G + P G+ P L+G P V G GP
Sbjct: 1286 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV-- 1343
Query: 307 HQPQGAWPEEAVGT-GPAYPLPTQPAPSPLPCY---QGQPGGLNRHSDLSGALSSPGAAH 362
P A PE G GP P P P PS P G+ L G L P
Sbjct: 1344 --PGSAGPEGEPGLIGPPGP-PGLPGPSGQSIIIKGDAGPPGIPGQPGLKG-LPGPQGPQ 1399
Query: 363 SAPRPFSDSLHKSLTKILPERPPSAQ-----DGLGSTRGPPSSLPQRHFPGQAYRAS--- 414
P P P P DG G +G P PGQ
Sbjct: 1400 GLPGPTG-----------PPGDPGRNGLPGFDGAGGRKGDPG------LPGQPGTRGLDG 1442
Query: 415 -----GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT 450
G+ PGPP T A G R Q D P T
Sbjct: 1443 PPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1483
Score = 52.0 bits (123), Expect = 1e-05
Identities = 117/458 (25%), Positives = 144/458 (31%), Gaps = 74/458 (16%)
Query: 3425 VRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLC 3484
+ +PG PG L G P + V +PG PG+ P G E +P +
Sbjct: 659 ITQPGKPG-----LPGN-PGRDGDVGLPGDPGLPGQPGLP--GIPGSKGEPGIPGI---- 706
Query: 3485 SEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALD 3544
P KG+P P P T G E P P P P AL G L
Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP-GFALPGPPGPPGLP 765
Query: 3545 G---ALERPENEASPGSPGPLLQQALPLGASLPRP----GARGQDAEGKRAPLVFSGKRR 3597
G AL + PG PGP + L LP P G GQ L G +
Sbjct: 766 GFKGALGPKGDRGFPGPPGPPGRTGLD---GLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822
Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSA 3657
PG G P H + EK + GP G +GS P
Sbjct: 823 PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG--ERGSPGIPG----------- 869
Query: 3658 ASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG 3717
A P P P KA S PG T+ M P PGP S PG K
Sbjct: 870 APGPIGPPGSPGLPGKAGASGFPG-----TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924
Query: 3718 GGSQPQPA-------SGQLQSETATTPAKPSFPS--------RSPAPERLPARAQAKSCT 3762
G Q QP G P P P+ P +P + K
Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984
Query: 3763 KGPREAGEQGPHGSLG----PKEKGESSTKRKKGQVPGPARSESVGSFG-RAPSAPDKPP 3817
P + G+ G G G P KG + G + P ++G G P + PP
Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044
Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855
PS V P P P + K +PG
Sbjct: 1045 -------GPSGV------PGQPGSPGLPGQKGDKGDPG 1069
Score = 51.6 bits (122), Expect = 2e-05
Identities = 170/687 (24%), Positives = 226/687 (32%), Gaps = 102/687 (14%)
Query: 871 EEPSGPRGPSSGHPLKSKAGVTPES-KAPPPLPAATPDPQTP-RPGDRGCPA-RGRPKTR 927
E P GPRG + G P+ + PP LP P P PG G P +G P
Sbjct: 68 EGPPGPRGQKGDDGIPGPPG--PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIP--- 122
Query: 928 SLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR-PRRNDGL 986
G T+ + G G Q G G G S L P+ N G
Sbjct: 123 --GCNGTKGERGFPGSPGFPGLQ-----GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY 175
Query: 987 GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046
P + T PG P P P + + P+ K G
Sbjct: 176 PGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235
Query: 1047 GKELILKIVQQKNRLREYDFASESE--EDEQPPPRGPGFRGRRG--RGEKRKEVELTQGP 1102
G + ++ R + +F + ++ PP PG RG G GEK ++ E
Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----- 290
Query: 1103 REDEPQKPRKAARQ-EAGGDGAPANPEEPGGSRPG-PGRSPQARGPSRSLETGAAAREG- 1159
+ EP K K + E G G P P +PG PG PGR + + +TG G
Sbjct: 291 -QGEPGKRGKPGKDGENGQPGIPGLPGDPG--YPGEPGRDGE---KGQKGDTGPPGPPGL 344
Query: 1160 -GPKCADRPSVAPKDPLQVP-TNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217
P+ ++ K + +P E E P + P P A P
Sbjct: 345 VIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG------- 397
Query: 1218 RSPPAACAGEMG-----ASPGLLIPEQP-----PPSRHDTGTPKPSG-------SLANTA 1260
P GE G PG+ IP P P + G P P+G +
Sbjct: 398 ---PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454
Query: 1261 PHGSSPTPGVGSLLGGPG--GTQAPVSHN----SKDPPARQPGEFLAPVANPSSTACPKP 1314
P G +PG L G G G + N P QPG P P S P
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP-GPPGSLGFPGQ 513
Query: 1315 SVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSEL-FLGPKDLAGCFLEELHPK 1373
+ + G P G P G P A P P L F G K G EL
Sbjct: 514 KGEKGQAGATG--PKGLPGIP-GAPGAPGFPGSKGEPGDILTFPGMKGDKG----EL-GS 565
Query: 1374 PSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPG--TAETEPGRAASPPTLESSSLFPDL 1431
P A P + G+D P P+ PG T + E G +P P L
Sbjct: 566 PGAPGLPGLPGT----PGQDGLPGLPG-PKGEPGGITFKGERGPPGNPG-------LPGL 613
Query: 1432 P--VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD 1489
P + PP +G + G+ +P Q +P P + + P LP + P
Sbjct: 614 PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN-PG 672
Query: 1490 LSGGKVLSKTCPPERTVVPGAAPSLPG 1516
G L P +PG P LPG
Sbjct: 673 RDGDVGL-----PGDPGLPG-QPGLPG 693
Score = 47.8 bits (112), Expect = 2e-04
Identities = 113/463 (24%), Positives = 147/463 (31%), Gaps = 74/463 (15%)
Query: 3432 GQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPST 3491
G K E P +PG PGP E P PRG + +P P
Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGF-PGP-EGPPGPRGQK---GDDGIPGPPGPKGIRGPPG 96
Query: 3492 TKGWPETLERPV------DPVTHPIRGCELPSNHQECPP----PSLS--PFPAALADGRG 3539
G+P T P P I GC + P P L P P + +G
Sbjct: 97 LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156
Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-------------RPGARGQDAEGK 3586
+ P + +PG PGP Q LP +P PG G
Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216
Query: 3587 RAPLVFSGKRRAPGARGRCAP-----DHFQEDHLLQKEKEVSSSHMVSEGGPRG-TFHKG 3640
L F G + G +G P ++ + E + + + GP G +G
Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276
Query: 3641 SATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA-----PGELARGTENGMKPAT 3695
P G + ++ K K + + + L PGE R E G K T
Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT 336
Query: 3696 PKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPAR 3755
PGP G PRPGT G + L E + FP P LP
Sbjct: 337 --GPPGP--PGLVIPRPGTGITIGEKGNIGLPGLPGE----KGERGFPG-IQGPPGLP-- 385
Query: 3756 AQAKSCTKGPREAGEQGPHGSLG-PKEKGESSTKRKKG-QVPGPARSESVGSFGRAPSAP 3813
GP A GP G G P E+G+ + G +PGP + P AP
Sbjct: 386 --------GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG------QPGAP 431
Query: 3814 DKP-PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855
P P P P +P P P PP S K G
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGP-----PGPPGSPGDKGLQG 469
Score = 45.8 bits (107), Expect = 8e-04
Identities = 119/518 (22%), Positives = 164/518 (31%), Gaps = 84/518 (16%)
Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLP 3478
P ++G+ PG PGQ + + LP PG PG PP G + + P
Sbjct: 980 PKGYQGL--PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP--GLKGTIGDMGFP 1035
Query: 3479 ALLHLCSEVAPSTTKGWPETLERPV------DPVTHPIRGCELPSNHQECPPPSLSPFPA 3532
+ PS G P + P DP I LP E P L +P
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE---PGLPGYP- 1091
Query: 3533 ALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG-------QDAE 3584
G+ + G++ P PG+PG Q LP P PG +G
Sbjct: 1092 ------GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145
Query: 3585 GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATK 3644
G+ P+ G PG G E ++ + E G G + G
Sbjct: 1146 GEPGPVGGGGHPGQPGPPG--------EKGKPGQDGIPGPAGQKGEPGQPGFGNPG---- 1193
Query: 3645 PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSS 3704
P G S + P P +P PG G P P PGP+
Sbjct: 1194 PPGLPGLSGQKGDGGLPG----IPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPAL 1247
Query: 3705 QG-SGSPRP----------GTKTGGGSQPQPASGQLQSETATTPAKPSFP--------SR 3745
+G G+P P G G P +G ++ E P +P P
Sbjct: 1248 EGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKG-NPGQPGLPGLPGLKGDQG 1306
Query: 3746 SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK-EKGESSTKRKKGQV--------PG 3796
P + P R P G G G GP G + + + G + PG
Sbjct: 1307 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG 1366
Query: 3797 PA-RSESVGSFGRAPSAPDKP--PRTPRKQATPSRVLPTKP--KPNSQNKPRPPPSEQRK 3851
P+ +S + P P +P P Q PT P P P + RK
Sbjct: 1367 PSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRK 1426
Query: 3852 AEPGHTQRKDRLGKAFPQGRPLLR----PPKRGTAVHG 3885
+PG + G P G L+ PP + HG
Sbjct: 1427 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHG 1464
Score = 44.7 bits (104), Expect = 0.002
Identities = 115/475 (24%), Positives = 140/475 (29%), Gaps = 62/475 (13%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG PG + LP PG GE PP P L L +
Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN-----------PGLPGLPGNI 617
Query: 3488 APSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546
P G+ P PV I+G P P P G+ L G
Sbjct: 618 GPMGPPGF-----GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP--GLPGN 670
Query: 3547 LERPENEASPGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF---SGKRRAPGAR 3602
R + PG PG Q LP + S PG G G P F G APG
Sbjct: 671 PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTP 730
Query: 3603 GRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPS 3662
GR + K + GP G A P G DR P
Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPG 784
Query: 3663 ----------KALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRP 3712
K V P G + P L G P P PGP Q P
Sbjct: 785 PPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG--PPGPPGIPGPIGQPGLHGIP 842
Query: 3713 GTKTGGGSQPQPASGQL-QSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ 3771
G K G G + + P P P P LP +A A E G
Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMM 901
Query: 3772 GPHGSLGPKE----------KGESSTKRKKGQVPGPARSESVGSFGR----APSAPDKPP 3817
GP G GP KG+ + + G +PGP + GS G P P P
Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEK--GSKGEPGLPGPPGPMDPN 958
Query: 3818 RTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
K LP P + + P + +PG + + G P+G P
Sbjct: 959 LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLPGPPGPKGNP 1011
Score = 43.5 bits (101), Expect = 0.004
Identities = 199/866 (22%), Positives = 253/866 (29%), Gaps = 161/866 (18%)
Query: 1752 PGTADQPHR-GAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGR 1810
PG QP G P P P + + ++ G PP G+ QG +
Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP-------GSPGDKGLQGEQGVK 474
Query: 1811 A----------GGHLHPTAGRPGFEGNEFAPA-----------GASSLTAPRGREAWLVP 1849
G + G+PG G P G + T P+G L
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG----LPG 530
Query: 1850 VPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNP 1909
+P P + P L PG K + G G L +P +
Sbjct: 531 IPGA-------PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583
Query: 1910 SGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGT 1969
GL G E G + +G PG + LP G +G G G +G EK
Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG-PMGPPGFGPPGPVG--EKGIQGVA 640
Query: 1970 ANQLQPENGVSPGGTDNHASVNASPKTALTG--PTEGAVLLEKCKGSRAAMSLQ----EE 2023
N QP G+ D ++ K L G +G V L G L +
Sbjct: 641 GNPGQP--GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698
Query: 2024 AEP------TPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077
EP P PP P G+ G TP R GL P G P P
Sbjct: 699 GEPGIPGIGLPGPPGPK------GFPGIPGPPGAPG-TPGRI---GLEGPPGPPG-FPGP 747
Query: 2078 SVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQL 2137
G+ P P +P G L P +G G PPGP
Sbjct: 748 K-GEPGFALPGPPGPPGLPGFKGAL-------GPKGDRGFPG-----------PPGP--- 785
Query: 2138 LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDP 2197
P L+ G + + P+ PP L G +QG P P
Sbjct: 786 ----PGRTGLDGLPGPKGDVGPNGQPGPMGPP-----------GLPGIGVQGPPGPPGIP 830
Query: 2198 SSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRA 2257
P G P L +P PG SP + GA P +
Sbjct: 831 G--PIGQPGLHGIPGEKGDPGPPGLDVP---------GPPGERGSPGIPGAPGPIGPPGS 879
Query: 2258 TGL-----SSTPTGDEAQAG-RGLPGPD-----PQSRGAPPHTNPDRMPRGHSSYSPSNT 2306
GL +S G + + G G PGP P G P D + P+
Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939
Query: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKE-----PEDPGTPETGRSG 2361
G P +P L G L G G S + P DPG P G SG
Sbjct: 940 KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP--GLSG 997
Query: 2362 ATKMPRVTCPSTGLGL----GRTTAP--SSTASDFQSDSPQSHRNASHQTPQGDPLGP-Q 2414
+P P GL G P T D PQ P G P P
Sbjct: 998 QPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP--PGPSGVPGQPGS 1055
Query: 2415 DLKQRSRGYKKKPASTENGQWKGQAPHG-------PVTCEVCAASFRSG-PGLSRHKARK 2466
+G K P + G P G P + + G PGL K
Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115
Query: 2467 HRP----HPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVT 2522
+P PG P P P + L + P H G+ P +G P
Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH--PGQPGPPGEKGKPGQDG 1173
Query: 2523 QPPPAQGSKEVLRAPGSPHSQQLHPP 2548
P PA E PG P PP
Sbjct: 1174 IPGPAGQKGE----PGQPGFGNPGPP 1195
Score = 43.5 bits (101), Expect = 0.004
Identities = 236/1003 (23%), Positives = 303/1003 (30%), Gaps = 218/1003 (21%)
Query: 1684 GDSRPPQD-VCLPEPSKQPGPQLDAG-------------SLAKC---------------- 1713
G PP D +C P P PG D G + C
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500
Query: 1714 --SPDQELSFP--KNKEAASSQESEDSLRLLPCE-----------QRGGFLPEPG-TADQ 1757
P L FP K ++ + L +P + G L PG D+
Sbjct: 501 LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDK 560
Query: 1758 PHRGAPA----PEAFGSPAVHLAPDL----------AFQGDGAPPLDATWPFGASPSHAA 1803
G+P P G+P P L F+G+ PP + P P +
Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP--GLPGNIG 618
Query: 1804 QGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVP-SPACVSNTHPS 1862
G G G G +G P G + P+G + P P N P
Sbjct: 619 ---PMGPPGFGPPGPVGEKGIQGVAGNP-GQPGIPGPKGDPGQTITQPGKPGLPGN--PG 672
Query: 1863 RRSQ-----DPAL--------------SPPIRQLQLPGPGVAKSKDGILGLQEL--TP-- 1899
R DP L P I + LPGP K GI G TP
Sbjct: 673 RDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGR 732
Query: 1900 -AAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEAD-GHWGL 1957
+ PP P G G E G GP G PG LP G LG + D G G
Sbjct: 733 IGLEGPP--GPPGFPGPKGEPGFALPGP-PGPPG------LPGFKG-ALGPKGDRGFPGP 782
Query: 1958 LGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGP-----------TEGAV 2006
G +T G P+ V P G P + GP G
Sbjct: 783 PGPPGRTGLDGLPG---PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839
Query: 2007 LLEKCKGSRAAMSLQEEAEP-------TPSPPSPNRESLALALTAAHSRSGSEGRTPERA 2059
+ KG L P P P P + L SG G E
Sbjct: 840 GIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899
Query: 2060 --SSPGLNKPLLATGDSPAPSV-GDLAACA----PSPT---SAAHMPCSLGPLPREDPLT 2109
PG PL G S P + GD P PT + P GP DP
Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959
Query: 2110 SPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAP- 2168
S+ + G G LP P P G Q L P L G+ G + +P P
Sbjct: 960 LGSKGEKGEPG-LPGIPGVSGPKGYQGLPG-DPGQPGLSGQPGLPG--PPGPKGNPGLPG 1015
Query: 2169 -PSLTTSPCDPKEALAGCLLQG----EGSPLEDPSSWP--PGSVSAVTCTHSGDTPKDST 2221
P L P K + G EG P PS P PGS P S+
Sbjct: 1016 QPGL-IGPPGLKGTIGDMGFPGPQGVEGPP--GPSGVPGQPGSPGLPGQKGDKGDPGISS 1072
Query: 2222 LRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQ 2281
+ +P + PG +P + G+V GL P A+ GLPG P
Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKGSVGD------PGLPGLPGTPGAKGQPGLPG-FPG 1125
Query: 2282 SRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGE 2341
+ G P P+G S P N +P EP + G G GE
Sbjct: 1126 TPGPPG-------PKGISG-PPGN------------PGLPGEPGPVGGGGHPGQPGPPGE 1165
Query: 2342 MGTSSK--------EPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSD 2393
G + + +PG P G G +P ++ GL P +
Sbjct: 1166 KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL--PGIPGNPGLPGPKG 1223
Query: 2394 SPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKG-QAPHGPVTCEVCAAS 2452
P H Q P G P P + +G ++G P GP
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGP--------- 1274
Query: 2453 FRSGPGLSRHKARK-HRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERP 2511
PGL + K + +PG P P L Q PP + + G+
Sbjct: 1275 ----PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ---------GPPGLQGN--PGRPGL 1319
Query: 2512 NHSRGDPSHVTQPPPAQGSKEVLRAPGS--PHSQQ--LHPPSP 2550
N +GDP + P G K PGS P + + PP P
Sbjct: 1320 NGMKGDPG-LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1361
Score = 40.4 bits (93), Expect = 0.035
Identities = 56/209 (26%), Positives = 69/209 (33%), Gaps = 18/209 (8%)
Query: 3693 PATPKAKPGPSSQGSG---SPRPGTKTGGGSQPQPASGQLQSETATT----PAKPSFPSR 3745
P P PG + S PG K G P L T P P
Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204
Query: 3746 SPAPERLPA-RAQAKSCTKGPR-EAGEQGPHGSLGP-----KEKGESSTKRKKGQ--VPG 3796
P P LP + +GP+ E GEQG G GP ++K + +KG +PG
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264
Query: 3797 PARSESVGSFGRAPSAPDKPPRTPRKQATPS-RVLPTKPKPNSQ-NKPRPPPSEQRKAEP 3854
P P +Q P R P K N Q P P EP
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEP 324
Query: 3855 GHTQRKDRLGKAFPQGRPLLRPPKRGTAV 3883
G K + G P G P L P+ GT +
Sbjct: 325 GRDGEKGQKGDTGPPGPPGLVIPRPGTGI 353
Score = 37.7 bits (86), Expect = 0.23
Identities = 50/197 (25%), Positives = 62/197 (31%), Gaps = 35/197 (17%)
Query: 489 PTARPSPHGMEMLSRLPFPAG-----GPEWQGGSQGALGTAGK-----TPGPREKLPAVR 538
P P P G + +P P G GP G G G G PGP + +P
Sbjct: 67 PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP-QGIPGCN 125
Query: 539 SSQG-----GSPALFTYNGMTDPGAQPLFFG-----VAQPQVSPHGTPSLPPPRVVGASP 588
++G GSP G P P G + P G P P P + P
Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP 185
Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSA--FFHPPTHPQETGS 646
+ +P P P P P LPGP G F P E G
Sbjct: 186 GPTGIPGPIGPPG-------PPGLMGPPGPPG----LPGPKGNMGLNFQGPKGEKGEQGL 234
Query: 647 PFPSPEPPHSLPTHYQP 663
P P PP + +P
Sbjct: 235 QGP-PGPPGQISEQKRP 250
Score = 37.0 bits (84), Expect = 0.39
Identities = 169/712 (23%), Positives = 217/712 (30%), Gaps = 136/712 (19%)
Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASA 3265
P P+ G R G PG P + PG P P + DGA P
Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH-DGAPGPQGIPG 123
Query: 3266 T--ALADAGSPGPP-----RTTPSPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCG--- 3315
+ G PG P + P P P GEP + + + P + + G
Sbjct: 124 CNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKGNPGYPGPPG 180
Query: 3316 -KRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLY 3374
+ P P + + P + P P + G + + G G LQ P
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240
Query: 3375 ACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGAP--G 3432
++ I + F K +Q L G R P G+R P P G
Sbjct: 241 PGQISEQKRPI----------DVEFQKGDQ-------GLPGDRGPPGPPGIRGPPGPPGG 283
Query: 3433 QKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTT 3492
+K E P KR + PG+D E P +
Sbjct: 284 EKGEKGEQGEPGKRGK---------PGKD-----------GENGQPGI------------ 311
Query: 3493 KGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA--LADGRGDCALDGAL--- 3547
G P P +P +G + PP + P P +G+ L G
Sbjct: 312 PGLPGDPGYPGEPGRDGEKG-QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370
Query: 3548 -ER--PENEASPGSPGPLLQQALPLGASLPR--PGARGQDAEGKRAPLVFS-----GKRR 3597
ER P + PG PGP A +G P PG RGQ +G P S G
Sbjct: 371 GERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQ--KGDEGPPGISIPGPPGLDG 426
Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR-- 3655
PGA G P H + S + E GP G G Q D+
Sbjct: 427 QPGAPGLPGPPGPAGPH-------IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD 479
Query: 3656 -------SAASTPSKALKFPVHPRKAVGSLA----PGELARGTENGMK--PATPKAKPGP 3702
+ S P P P GSL GE + G K P P A P
Sbjct: 480 TCFNCIGTGISGPPGQPGLPGLPGPP-GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538
Query: 3703 SSQGS-GSPR-----PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756
GS G P PG K G P + L T P + P P P+ P
Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGL-PGPKGEPGGI 596
Query: 3757 QAKSCTKGPR----------EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSF 3806
K +GP G GP G P GE + G P G
Sbjct: 597 TFKG-ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655
Query: 3807 GRAPSAPDKP--PRTPRKQATPSRVLPTKP-KPNSQNKPRPPPSEQRKAEPG 3855
G+ + P KP P P + LP P P P P S K EPG
Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVG--LPGDPGLPGQPGLPGIPGS---KGEPG 702
Score = 36.6 bits (83), Expect = 0.50
Identities = 60/248 (24%), Positives = 80/248 (32%), Gaps = 28/248 (11%)
Query: 1689 PQDVCLPEPSKQPG----PQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQ 1744
P + LP P +PG P + SP L PK + LP +
Sbjct: 1213 PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPE 1272
Query: 1745 RGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQ 1804
LP G + +G P G P + P L +GD PP G +
Sbjct: 1273 GPPGLPGNGGI-KGEKGNP-----GQPGLPGLPGL--KGDQGPP-------GLQGNPGRP 1317
Query: 1805 GHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRR 1864
G + + L G PG +G P+G P G E L+ P P + P
Sbjct: 1318 GLNGMKGDPGLPGVPGFPGMKG----PSGVPGSAGPEG-EPGLIGPPGPPGL----PGPS 1368
Query: 1865 SQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVAC 1924
Q + +PG K G G Q L P +GL G GG+
Sbjct: 1369 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1428
Query: 1925 GPAQGSPG 1932
G PG
Sbjct: 1429 PGLPGQPG 1436
Score = 36.2 bits (82), Expect = 0.66
Identities = 105/488 (21%), Positives = 148/488 (30%), Gaps = 82/488 (16%)
Query: 2101 PLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLAC-----------------SPA 2143
P P+ P + ++ + G G P P + PPGP + +P
Sbjct: 116 PGPQGIPGCNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPG 174
Query: 2144 WAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP----KEALAGCLLQG-EGSPLEDPS 2198
+ G+ T P PP L P P + G QG +G E
Sbjct: 175 YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGL 234
Query: 2199 SWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRAT 2258
PPG ++ + + + + L G P + G P +
Sbjct: 235 QGPPGPPGQIS-------EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287
Query: 2259 GLSSTPTGDEAQAGR----------GLPGPDPQSRGAPPH---------TNPDRMPRGHS 2299
G + G+ GLPG DP G P T P P G
Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPP-GLV 345
Query: 2300 SYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDP-GTP-ET 2357
P +G + + +P E G P L G G + P P G P E
Sbjct: 346 IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405
Query: 2358 GRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLK 2417
G+ G P ++ P G+ AP + H S + + P GP
Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGP---HIPPSDEICEPGPPGPPG-- 460
Query: 2418 QRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGP----GLSRHKARKHRPHPGA 2473
S G K KG TC C + SGP GL PG
Sbjct: 461 --SPGDKGLQGEQGVKGDKGD------TCFNCIGTGISGPPGQPGL-----------PGL 501
Query: 2474 PAEPSPAALPAQQPLEPLAQKCQPPRKKS-HRVSGKERPNHSRGDPSHVTQPPPAQGSKE 2532
P P P Q+ + A P G S+G+P + P +G K
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKG 561
Query: 2533 VLRAPGSP 2540
L +PG+P
Sbjct: 562 ELGSPGAP 569
Score = 34.3 bits (77), Expect = 2.5
Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 16/133 (12%)
Query: 3183 LGDLPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPG 3240
L LPG G +G + + P PK G G PG G + PG
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164
Query: 3241 ERAKPRARSTPS--------NPDGAATPDSASATALA----DAGSPGPPRT--TPSPSPD 3286
E+ KP P G P L+ D G PG P P P +
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224
Query: 3287 PWAGGEPLLQATP 3299
P G P +Q P
Sbjct: 1225 PGFHGFPGVQGPP 1237
Score = 33.9 bits (76), Expect = 3.3
Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 16/121 (13%)
Query: 3186 LPG--GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAKKDS 3238
LPG GL G + + + P P+ G G PG P G +G+ S
Sbjct: 1013 LPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS 1072
Query: 3239 PGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSPSPDPWAGGEPLLQAT 3298
G P + P P P ++ D G PG P T P A G+P L
Sbjct: 1073 IGLPGLPGPKGEPGLPGYPGNPGIKG--SVGDPGLPGLPGT-------PGAKGQPGLPGF 1123
Query: 3299 P 3299
P
Sbjct: 1124 P 1124
Score = 33.1 bits (74), Expect = 5.6
Identities = 22/55 (40%), Positives = 22/55 (40%), Gaps = 3/55 (5%)
Query: 1232 PGLLIPEQPPPSRH---DTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283
PG PE PP R D G P P G P G PG L G PG AP
Sbjct: 62 PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 99.4 bits (246), Expect = 6e-20
Identities = 355/1598 (22%), Positives = 500/1598 (31%), Gaps = 249/1598 (15%)
Query: 80 GQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPEN 139
G S G P P G P P G G PP G + P
Sbjct: 2 GNEVSLEGGAGDGPLPPGGAGPGPGPG--PGPGAGKPPSAPAGG----------GQLPAA 49
Query: 140 PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPP--SSFTSTNYT 197
+ +P V P GPG G PG P E LG R P +S T+ +
Sbjct: 50 GAARSTAVPPVPGP-GPGPGPGPGPGSTSRRLDPK-EPLGNQRAASPTPKQASATTPGHE 107
Query: 198 SPSATPRPPAPGPPQSRGTSP---LQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAE 254
SP T A GP P LQ S Q SG S P + + VP
Sbjct: 108 SPRETR---AQGPAGQEADGPRRTLQVDS--RTQRSGRSPSVSPDRGSTPTSPYSVPQIA 162
Query: 255 PEP------IPKGSRPGGSPRGVSFQFPFPALH------GASTKPFPADVAGHAFTNGPL 302
P P I K S +P +F + G + P V N +
Sbjct: 163 PLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQM 222
Query: 303 VFAFHQPQGAWPEE-------AVGTGPAYPLPTQPAPSPLPCYQGQPGGL---NRHSDLS 352
A P + PA+ QP P PGG +R ++ +
Sbjct: 223 QRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETA 282
Query: 353 GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYR 412
A S PG A +A P + ++ P+ P + R P P +
Sbjct: 283 RATSVPGPAQAAAPP-------EVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAG 335
Query: 413 ASGVDTSPGPPDTELAAPGPP---PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG--- 466
+ + +L G A P A P P T + FN
Sbjct: 336 LGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQP--APSKGTPKIVFNDASK 393
Query: 467 QPSPGQRLCLPQSAPLPWPQVLPTARPSP-HGMEMLSRLPFPAGGPEWQGGSQGALGTAG 525
+ P P P P + P AR P G L + + Q A A
Sbjct: 394 EAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAA 453
Query: 526 KT---PGPREKLPAVRSSQG-GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH-------- 573
K P R P ++ GS + YN T Q P +PH
Sbjct: 454 KPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNP--TPHLVEKTEWL 511
Query: 574 --------------GTPS-LPPP-----------RVVGASPSESPLPSPATNTAGSTCSS 607
G P+ LPPP R G SP + P +G +
Sbjct: 512 CLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAK 571
Query: 608 LSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAK 667
SP+S+ + S+ S PL S P+ QE + P+ P P P +
Sbjct: 572 ASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKP------PPE 625
Query: 668 AFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQL 727
P PA G + TP PE +GG + PY + S S SL
Sbjct: 626 TTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGG-EAEDLVGKPY-SQDASRSPQSLS-- 681
Query: 728 DVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAH 787
D YSS + + G++ + S G G P PP+ P++ H
Sbjct: 682 ---------DTGYSSDGISSSQSEITGVVQQEVE--QLDSAGVTG-PHPPS----PSEIH 725
Query: 788 AGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEA 847
+ S + L A + PL +G P L + + D +L+ ++ E
Sbjct: 726 K-VGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEED 784
Query: 848 LNGMEY-----QSDNPEIDSSFIDV----FADEEPSGPRGPSSGHPLKSKAGVTPESKAP 898
+ E+ Q D E F + ++ G P P A +T E
Sbjct: 785 EDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMR 844
Query: 899 PPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKL----- 953
+ + + D RG K + P PSQ ++L
Sbjct: 845 RQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTG 904
Query: 954 FRKDLDSGGAAE---GSGSGGGG---------RASGLRPRRNDGLGERPPPR-PRRPRTQ 1000
+ + L GG+AE GSG+ GG ++G D LG+ P P R P +
Sbjct: 905 YEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELD-LGQGPDPSLDREPELE 963
Query: 1001 APGSRADPAPRV--PRAAALPEETRS---------------------SRRRRLPPRKDPR 1037
P R ++ LP T S SRR+RL K R
Sbjct: 964 MESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQR 1023
Query: 1038 KRKARGGAWGKELILKIVQQKNRLREYDFASESE---EDEQPPPRGPGFRGRRGRGEKRK 1094
K + R I +++ E + E E E EQ R + RR + E R
Sbjct: 1024 KARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELR- 1082
Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR-GPSRSLETG 1153
Q RE P + E D +P RS + PS SL++
Sbjct: 1083 ----AQRRRERSKTPPSNLSPIE---DASPTEELRQAAEMEELHRSSCSEYSPSPSLDSE 1135
Query: 1154 AAAREGGP----KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPD 1209
A A +GGP K ++ L PT T + T PS P ++AEE+ +
Sbjct: 1136 AEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPL-----KSAEEAYEE 1190
Query: 1210 STEFTEALRSPPAACAGEMGASPGLLIPEQPPPSR------HDTGTPKPSGSLANTAPHG 1263
E L+ AG G G P QP R + T + G A A G
Sbjct: 1191 MMRKAELLQRQQGQAAGARGPHGG---PSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEG 1247
Query: 1264 SSPTPGVG---SLLGGPGGTQAPVSHNSKD---------------------PPARQPGEF 1299
+ + G +L +S+D P +Q G
Sbjct: 1248 TPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGP 1307
Query: 1300 LAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGP 1359
L P +P+ A P S+ SS D +G P V V + + P +L P
Sbjct: 1308 LTPGTSPTQLAAPVS--FSTPTSS---DSSGGRVIP-DVRVTQHFAKETQDP-LKLHSSP 1360
Query: 1360 KDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLP---RSPPGTAETEPGRA 1416
+ E P P ++ C G G + P P P + T
Sbjct: 1361 ASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYG 1420
Query: 1417 ASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLL 1476
SP T S DLP + L + A R+ P + +D T Y F
Sbjct: 1421 HSPTTANYGSQTEDLP--QAPSGLAAAGRAAREK--PLSASDGEGGTPQPSRAYSYFASS 1476
Query: 1477 E-EVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPS 1513
+SP PS P S GK+ + T P AP+
Sbjct: 1477 SPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPA 1514
Score = 55.5 bits (132), Expect = 1e-06
Identities = 175/788 (22%), Positives = 258/788 (32%), Gaps = 155/788 (19%)
Query: 1783 GDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAP-R 1841
GDG P P GA P G G P AG+P APAG L A
Sbjct: 12 GDGPLP-----PGGAGPG---PGPGPG-------PGAGKP-----PSAPAGGGQLPAAGA 51
Query: 1842 GREAWLVPVPSPACVSNTHPSRRSQDPALSP--PIRQLQLPGPGVAKSKDGILGLQELTP 1899
R + PVP P P S L P P+ + P ++ TP
Sbjct: 52 ARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQAS-------ATTP 104
Query: 1900 AAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLG 1959
+SP A GPA G EADG L
Sbjct: 105 GHESPRETR--------------AQGPA--------------------GQEADGPRRTLQ 130
Query: 1960 QAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMS 2019
+TQ G + + P+ G +P S + P+ A P + L CK S
Sbjct: 131 VDSRTQRSGRSPSVSPDRGSTP------TSPYSVPQIA---PLPSSTLCPICKTS----- 176
Query: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSE-GRTPERASSPGLN--KPLLATGDSPA 2076
+ TPS P+ N T H++ ++ G P +P L K L
Sbjct: 177 ---DLTSTPSQPNFN------TCTQCHNKVCNQCGFNP----NPHLTQVKEWLCLNCQMQ 223
Query: 2077 PSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQ 2136
++G AP S + P P SP++ G P R P GPQ
Sbjct: 224 RALGMDMTTAPRSKSQQQLHS-----PALSPAHSPAKQPLG----KPDQERSRGPGGPQ- 273
Query: 2137 LLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP---KEALAGCLLQGEGSP 2193
+A+ +AT+ G + P SP P K + A +P
Sbjct: 274 --------PGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAP 325
Query: 2194 LEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATS--PPLAGAVSP 2251
+ ++ P G + A T G T K L ++ L A + P +P
Sbjct: 326 AKSATAVPAG-LGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTP 384
Query: 2252 SVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAP-----PHTNPDRMPRGHSSYSPSNT 2306
+ + P + G PGP P ++ P P + P +P+ + SP +
Sbjct: 385 KIVFNDASKEAGPKPLGSGPG---PGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKH- 440
Query: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMP 2366
G E QA + +P T+ P C + E+ SK P + T T R
Sbjct: 441 ---GRAEHQAASKAAAKPKTMPKERAICPLC-QAELNVGSKSPANYNTCTTCR------- 489
Query: 2367 RVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKK 2426
C G T +++ + Q+ R + PL P +Q G +
Sbjct: 490 LQVCNLCGF---NPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHR 546
Query: 2427 PASTENGQWKGQ----APHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAAL 2482
+ T + KG P GP+ + S ++ P S+ + P +EPS
Sbjct: 547 ASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK---ASPQAKPLRASEPSKTPS 603
Query: 2483 PAQQPLEPLAQKCQ-----PPRKKSHRVSGKERPNHSRGDPSH--VTQPPPAQGSKEVLR 2535
Q+ + K + PP + K + R +P+ V P A E
Sbjct: 604 SVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAED 663
Query: 2536 APGSPHSQ 2543
G P+SQ
Sbjct: 664 LVGKPYSQ 671
Score = 55.1 bits (131), Expect = 1e-06
Identities = 334/1501 (22%), Positives = 485/1501 (32%), Gaps = 239/1501 (15%)
Query: 54 QAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAE 113
+A M++ A PR +L P+L SP P + PL P + R
Sbjct: 224 RALGMDMTTA-PRSKSQQQLHSPAL-------------SPAHSPAKQPLGKPDQERSRGP 269
Query: 114 GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRT-EAQ 172
G P SR T T +AA PEV G + P +P P T E +
Sbjct: 270 GGPQP-------GSRQAETARATSVPGPAQAAAPPEV----GRVSPQPPQPTKPSTAEPR 318
Query: 173 PAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGA 232
P A E + P+ +T T T + G S L PE G
Sbjct: 319 PPAGEAPA-KSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLM-SVQPEADTQGQ 376
Query: 233 DSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADV 292
PA P F E P P GS PG P GA T+P
Sbjct: 377 ----PAPSKGTPKIVFNDASKEAGPKPLGSGPGPGP-----------APGAKTEPGARMG 421
Query: 293 AGHAFTNGPLVFAFHQPQ-GAWPEEAVGTGPAYP--LPTQPAPSPL---PCYQGQPGGLN 346
G P P+ G +A A P +P + A PL G N
Sbjct: 422 PGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPAN 481
Query: 347 RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDG-LGSTRGPPSSLPQRH 405
++ + L P P + K+ L + +G LG P Q+
Sbjct: 482 YNTCTTCRLQVCNLCGFNPTP--HLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539
Query: 406 FPGQAYRASGVDTSPGPPDTELAAP-GPPPARLPQLWDPTAAPYP---TPPGGPLAATRS 461
G +RASG L P GP PA+ L A+P P +P PL A+
Sbjct: 540 PVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPL-STKASPLPSKASPQAKPLRASEP 598
Query: 462 MFFNGQPSPGQ--RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRL-------PFPAGGPE 512
+ PS Q + +P A P P+ P P+P ++ S + P PE
Sbjct: 599 ---SKTPSSVQEKKTRVPTKAE-PMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPE 654
Query: 513 WQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP 572
G G A G A RS Q S ++ +G++ +Q GV Q +V
Sbjct: 655 APKG-----GEAEDLVGKPYSQDASRSPQSLSDTGYSSDGIS--SSQSEITGVVQQEVE- 706
Query: 573 HGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPS 632
L V G P P+ + SS+ P+ + SE S+
Sbjct: 707 ----QLDSAGVTGPHP-------PSPSEIHKVGSSMRPLLQAQGLAPSERSK-------- 747
Query: 633 AFFHPPTHPQETGSPFPSPEPPHSL---PTHYQPEPAKAFPFPADGLGAEGAFQCLEE-- 687
P +G+ + PHSL P + + D AE + ++
Sbjct: 748 --------PLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDT 799
Query: 688 --------TPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRN 739
+ H+ E G G PP P L+ + +L + D
Sbjct: 800 AESSDDFGSQLRHDYVEDSSEG--GLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNL 857
Query: 740 YSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP------RVPADAHAGLLSH 793
A GL AK G Q+ GP P P P R+P +A G +
Sbjct: 858 EEDDTATSGR----GL----AKHGTQKG-GPRPRPEPSQEPAALPKRRLPHNATTG---Y 905
Query: 794 AKTFLLAGDAQAEGKDDPLRTGF----LPSLAATPFPLPASDLDMEDDAKLD---SLITE 846
+ G A+A L+ G L +T DL D LD L E
Sbjct: 906 EELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEME 965
Query: 847 ALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATP 906
+L G E S+ P+ +SG S + + +S + P
Sbjct: 966 SLTGSPEDRSRGEHSSTL--------PASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLE 1017
Query: 907 DPQTPRPGDRGCPARGRPKTRSLG-LAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAE 965
+ + R + + RS G L PT D+ S+ + R ++L ++ + E
Sbjct: 1018 EAKQQR----------KARHRSHGPLLPTIEDS-SEEEELREEEEL---LREQEKMREVE 1063
Query: 966 GSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSR------ADPAPRVPRAAALP 1019
R++ + RR+ E + RR R++ P S A P + +AA +
Sbjct: 1064 QQRI----RSTARKTRRDK---EELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEME 1116
Query: 1020 EETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPR 1079
E RSS P + +A G G + K + N S +E P
Sbjct: 1117 ELHRSSCSEYSPSPSLDSEAEALDG--GPSRLYKSGSEYNLPTFMSLYSPTE-----TPS 1169
Query: 1080 GPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGR 1139
G GR K E + R+ E + ++ Q AG G P +P G R
Sbjct: 1170 GSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQG--QAAGARGPHGGPSQPTGPRGLGSF 1227
Query: 1140 SPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTN-TETSEETRPSLDFPQEAK 1198
Q + A EG P A + ++ LQ + + + L F ++ K
Sbjct: 1228 EYQDTTDREYGQAAQPAAEGTP--ASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK 1285
Query: 1199 EPE---TAEESAPDSTEFTEALRSP---PAACAGEMG--------ASPGLLIPEQPPPSR 1244
+ + AE + D + +P P A + +S G +IP+
Sbjct: 1286 KEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQH 1345
Query: 1245 HDTGTPKPSGSLANTAPHGSSPTPGVGSLLG-GPGGTQAPVSHNSKDPPARQPGEFLAPV 1303
T P L ++ SS + +G GPG P + PA P ++ P
Sbjct: 1346 FAKETQDPL-KLHSSPASPSSASKEIGMPFSQGPG---TPATTAVAPCPAGLPRGYMTPA 1401
Query: 1304 ANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLA 1363
+ S P P SS S+G P N Y S +L P LA
Sbjct: 1402 SPAGSERSPSP---SSTAHSYGHSPTTAN---------------YGSQTEDLPQAPSGLA 1443
Query: 1364 GCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLE 1423
SA D + A S P P SP + PG+ T E
Sbjct: 1444 AAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAE 1503
Query: 1424 SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPML 1483
S+ P P D P R G P Q T P L+ +E S
Sbjct: 1504 FSTQTPS-PAPASDMP--------RSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEA 1554
Query: 1484 P 1484
P
Sbjct: 1555 P 1555
Score = 50.4 bits (119), Expect = 3e-05
Identities = 75/322 (23%), Positives = 110/322 (34%), Gaps = 59/322 (18%)
Query: 3588 APLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAG 3647
AP+ FS + + GR PD H ++ ++ H S P SA+K G
Sbjct: 1319 APVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS-SPASP------SSASKEIG 1371
Query: 3648 CQSSSKDRSAAST-----PSKALKFPVHPRKAVGS-LAPGELARGTENGMKPAT------ 3695
S + A+T P+ + + P GS +P + G P T
Sbjct: 1372 MPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQ 1431
Query: 3696 ----PKAKPGPSSQGSGSPRP--GTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAP 3749
P+A G ++ G + G G PQP+ +++ P PS PS SP
Sbjct: 1432 TEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESP-- 1489
Query: 3750 ERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA 3809
T P G +GP+ E ST Q P PA + + R+
Sbjct: 1490 ------------TFSP---------GKMGPRATAEFST-----QTPSPAPASDM---PRS 1520
Query: 3810 PSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQ 3869
P AP P + TP R P+ P+ Q + P + R+ A
Sbjct: 1521 PGAPTPSPMVAQGTQTPHR--PSTPRLVWQESSQEAPF-MVITLASDASSQTRMVHASAS 1577
Query: 3870 GRPLLRPPKRGTAVHGAEPAEP 3891
PL P + HG P
Sbjct: 1578 TSPLCSPTETQPTTHGYSQTTP 1599
Score = 46.6 bits (109), Expect = 5e-04
Identities = 163/724 (22%), Positives = 230/724 (31%), Gaps = 123/724 (16%)
Query: 3222 GSPGD---PWGQEGEAKKDSPGERAKPRARSTPSNPDGAAT-PDSASATALADAGSPGPP 3277
G GD P G G PG P A PS P G P + +A + A PGP
Sbjct: 9 GGAGDGPLPPGGAGPGPGPGPG----PGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPG 64
Query: 3278 RTTPSPSPDPWAGG--------EPL-------------LQATPVHEACKDPSRDCHHCGK 3316
P P P P G EPL TP HE+ ++ +R G+
Sbjct: 65 ---PGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRE-TRAQGPAGQ 120
Query: 3317 RFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLYAC 3376
P +R L V S R R P V P+ G + P P+ C
Sbjct: 121 EADGP---RRTLQVDS--RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPI--C 173
Query: 3377 ELCATVMRIIKKSF-ACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFR-------GVRRP 3428
+ + +F C+ C+ + F+ N HL ++ G+
Sbjct: 174 KTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNP--NPHLTQVKEWLCLNCQMQRALGMDMT 231
Query: 3429 GAPGQKAR------ALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLH 3482
AP K++ AL ++ + P G P P GS A
Sbjct: 232 TAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQP---------GSRQAETA 282
Query: 3483 LCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCA 3542
+ V P + R P + PS + PP +P +A A G A
Sbjct: 283 RATSVPGPAQAAAPPEVGRVSPQPPQPTK----PSTAEPRPPAGEAPAKSATAVPAGLGA 338
Query: 3543 LDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAP-LVFSGKRRAPGA 3601
+ E + G LL QA L + P +GQ A K P +VF+ + G
Sbjct: 339 TEQTQEGLTGKLF-GLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGP 397
Query: 3602 RGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTP 3661
+ + K + M GP G+ K G S R+
Sbjct: 398 KPLGSGPG---PGPAPGAKTEPGARMGPGSGP------GALPKTGGTTSPKHGRAEHQAA 448
Query: 3662 SKALKFP--VHPRKAVGSLAPGELARGTE---NGMKPATPKAKPGPSSQGSGSPRPGTKT 3716
SKA P + +A+ L EL G++ N T + + + +P KT
Sbjct: 449 SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKT 508
Query: 3717 GGGSQPQPASGQLQSETAT-TPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHG 3775
L+ TP P P+ P P RA S K + G QG
Sbjct: 509 EWLCLNCQTKRLLEGSLGEPTPLPP--PTSQQPPVGAPHRASGTSPLK---QKGPQGLGQ 563
Query: 3776 SLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPK 3835
GP S K +P A ++ P +P +TP +PTK +
Sbjct: 564 PSGPLPAKASPLSTKASPLPSKASPQA------KPLRASEPSKTPSSVQEKKTRVPTKAE 617
Query: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHR 3895
P P+PPP + P PK + V AEPA P
Sbjct: 618 P----MPKPPP----------------------ETTPTPATPKVKSGVRRAEPATPVVKA 651
Query: 3896 TAEA 3899
EA
Sbjct: 652 VPEA 655
Score = 46.2 bits (108), Expect = 6e-04
Identities = 99/391 (25%), Positives = 129/391 (32%), Gaps = 89/391 (22%)
Query: 2324 PPTLQGAGPDSPACLEGEMGTSSKEPEDPG----TPETGRSGATKMPRVTCPSTGLGLGR 2379
PP G GP G + K P P P G + +T +P V P G G G
Sbjct: 17 PPGGAGPGPGP-----GPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPG- 70
Query: 2380 TTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQA 2439
P ST+ P ++ A+ TP+ + G++ P T GQ
Sbjct: 71 -PGPGSTSRRLDPKEPLGNQRAASPTPK-------QASATTPGHES-PRETRAQGPAGQE 121
Query: 2440 PHGPV-TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPP 2498
GP T +V + + RSG S R P SP ++P PL P + C P
Sbjct: 122 ADGPRRTLQVDSRTQRSGRSPSVSPDRGSTP-------TSPYSVPQIAPL-PSSTLC-PI 172
Query: 2499 RKKSHRVSGKERPNHSRGDPSH--------VTQPPPAQGSKEVL---------------R 2535
K S S +PN + H P KE L
Sbjct: 173 CKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTT 232
Query: 2536 APGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDS 2595
AP S QQLH P+ + K P K PDQ R
Sbjct: 233 APRSKSQQQLHSPALSPAHSPAKQPLGK--PDQER------------------------- 265
Query: 2596 PSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEG 2655
S G + G + R S+ P A + R SP P+ + E
Sbjct: 266 ---SRGPGGPQPGSRQAETARATSV-PGPAQAAAPPEVGRVSP----QPPQPTKPSTAEP 317
Query: 2656 GPEADGEQPPRLATLGPGVMEGAAETDQEAL 2686
P A GE P + AT P + GA E QE L
Sbjct: 318 RPPA-GEAPAKSATAVPAGL-GATEQTQEGL 346
Score = 46.2 bits (108), Expect = 6e-04
Identities = 87/381 (22%), Positives = 121/381 (31%), Gaps = 64/381 (16%)
Query: 2222 LRIPEDSRKEK-------LWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRG 2274
L ED +KEK + P + PL SP+ S TPT ++ GR
Sbjct: 1278 LAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFS-TPTSSDSSGGRV 1336
Query: 2275 LPGPDPQSRGAPPHTNPDRMPRGHSS-YSPSNTAR---LGHREGQAVTAVPTEPPTLQGA 2330
+P A +P ++ HSS SPS+ ++ + +G A P G
Sbjct: 1337 IPDVRVTQHFAKETQDPLKL---HSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGL 1393
Query: 2331 G-----PDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSS 2385
P SPA E SS +P T G+ PS GR
Sbjct: 1394 PRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKP 1453
Query: 2386 -TASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPV 2444
+ASD + +PQ R S+ PL P + K ++ Q P
Sbjct: 1454 LSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTP---- 1509
Query: 2445 TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKS-- 2502
APA P + A P +AQ Q P + S
Sbjct: 1510 --------------------------SPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTP 1543
Query: 2503 ---HRVSGKERP---NHSRGDPSHVTQPPPAQGSKEVLRAPGSPHS-----QQLHPPSPT 2551
+ S +E P D S T+ A S L +P Q PPS +
Sbjct: 1544 RLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVS 1603
Query: 2552 EHEVDVKTPASKPRPDQARED 2572
+ + P PR A D
Sbjct: 1604 QLPPEPPGPPGFPRVPSAGAD 1624
Score = 43.5 bits (101), Expect = 0.004
Identities = 91/344 (26%), Positives = 122/344 (35%), Gaps = 59/344 (17%)
Query: 141 QLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPS 200
+L +L TP G P P T + P A FQ+P + Y++ S
Sbjct: 3016 ELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTA--------FQQPRFQPPAPQYSAGS 3067
Query: 201 ATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPE-PIP 259
G P G Q +YP A ++P PGA++ PAEP P
Sbjct: 3068 --------GGPTQNGFPAHQAPTYPGPSTYPAPAFP-------PGASY---PAEPGLPNQ 3109
Query: 260 KGSRPGG-------SPRGVSFQFPFPALHGAS-TKPFP---ADVAGHAFTNGPLVFAFHQ 308
+ RP G P S FP PA A KP AD+ TN ++ +
Sbjct: 3110 QAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVV 3169
Query: 309 PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPF 368
P + P E +GPA + QG+ + R D SP AP
Sbjct: 3170 PMSSAPSETSYSGPAVSSGYE---------QGKVPEVPRAGDRGSVSQSP-----APTYP 3215
Query: 369 SDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLP--QRHFPGQAYRASGVDTSPGPPDTE 426
SDS + SL + +P D T+ S+ P QR P + PG P
Sbjct: 3216 SDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGV- 3274
Query: 427 LAAPGPPPARLPQLWDPTAAPY-PTPPGGPLAATRSMFFNGQPS 469
L P P + Y P GG L RSM NG+P+
Sbjct: 3275 LDGPTLPCCYARGEEESEEDSYDPRGKGGHL---RSMESNGRPA 3315
Score = 42.7 bits (99), Expect = 0.007
Identities = 168/743 (22%), Positives = 230/743 (30%), Gaps = 186/743 (25%)
Query: 2651 LSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKP-------------- 2696
+S+EGG DG PP A GPG G + AG G Q P
Sbjct: 5 VSLEGGA-GDGPLPPGGAGPGPGPGPGPGAGKPPSAPAG--GGQLPAAGAARSTAVPPVP 61
Query: 2697 -----------PGD--RMLCPGRMDGAALGEQPTG-QKGASARGFWGPRETKALGVCKES 2742
PG R L P G PT Q A+ G PRET+A G +
Sbjct: 62 GPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQE 121
Query: 2743 GSEP-----AEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSC----LQGL 2793
P + ++ RS + + P P P+ + P+ + C L
Sbjct: 122 ADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTST 181
Query: 2794 PDNPDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKR 2853
P P+ Q ++V F P LT+
Sbjct: 182 PSQPNFNTCTQ--------------------CHNKVCNQCGFNPNPHLTQV--------- 212
Query: 2854 CEKPVLPLPTQPSFEEGGDPTLGPARLPTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLD 2913
K L L Q G D T P S +L H + P G P+
Sbjct: 213 --KEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPA---KQPLGKPDQE--- 264
Query: 2914 GFLNSRVPGIDPWAPGLSLWALEPSREAGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLE 2973
SR PG PG SR+A + S P + A PE+ G
Sbjct: 265 ---RSRGPGGPQ--PG--------SRQAETARATS-VPGPAQAAAPPEV--------GRV 302
Query: 2974 MPAPADDSSSSLGDVSPEPPSLER---------------ERCDGGLPGNTHLLPLRATDF 3018
P P + S + P PP+ E E+ GL G L L A+
Sbjct: 303 SPQPPQPTKPSTAE--PRPPAGEAPAKSATAVPAGLGATEQTQEGLTGK--LFGLGASLL 358
Query: 3019 EVLSTKFEMQDLCFLGPFEDPVGLPGPSF----LDFEGTASSQGPQ------------SR 3062
ST +Q P D G P PS + F + GP+
Sbjct: 359 TQASTLMSVQ------PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGA 412
Query: 3063 RTEEAAGAGRAQGRGR-PAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPT----- 3116
+TE A G G G P G S K G + + A P T
Sbjct: 413 KTEPGARMGPGSGPGALPKTGGTTSPKH----------GRAEHQAASKAAAKPKTMPKER 462
Query: 3117 --CYMC-VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNE--HLREHAV 3171
C +C E GS+ S A C C +V ++ +N HL E
Sbjct: 463 AICPLCQAELNVGSK-------------SPANYNTCTTCRLQVCNLCGFNPTPHLVEKTE 509
Query: 3172 RFARRGQARR----SLGD---LPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAG-- 3222
Q +R SLG+ LP V + + +P +G + G+ +G
Sbjct: 510 WLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVG-APHRASGTSPLKQKGPQGLGQPSGPL 568
Query: 3223 -SPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTP 3281
+ P + +AKP S PS + A+ PP TTP
Sbjct: 569 PAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTP 628
Query: 3282 SP-SPDPWAGGEPLLQATPVHEA 3303
+P +P +G ATPV +A
Sbjct: 629 TPATPKVKSGVRRAEPATPVVKA 651
Score = 42.4 bits (98), Expect = 0.009
Identities = 71/273 (26%), Positives = 96/273 (35%), Gaps = 42/273 (15%)
Query: 47 GAREAGGQAQAMELP----EAQPRQARDGELKPPSLRGQA-PSSTPGKRGSPQTPPGRSP 101
G EA +Q P + QP E PS A ++ K+GS Q G +
Sbjct: 3675 GRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAA 3734
Query: 102 LQ------APSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQG 155
LQ A +L GR PQ+ SSR P+ PQ + Q QG
Sbjct: 3735 LQSKAEPQAQPQLQGRQAAPGPQQS--QSPSSRQIPS-GAASRQPQTQQQQ-------QG 3784
Query: 156 PGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRG 215
G QP + L R Q+ S +T ++P+A+ P P S
Sbjct: 3785 LGL-------------QPPQQALTQARLQQQ---SQPTTRGSAPAASQPAGKPQPGPSTA 3828
Query: 216 TSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQF 275
T P G Q +G+ A + P P + G+RPGG+P + Q
Sbjct: 3829 TGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ- 3887
Query: 276 PFPALHGAS--TKPFPADVAGHAFTNGPLVFAF 306
P G S +K P A A V AF
Sbjct: 3888 --PGADGESVFSKILPGGAAEQAGKLTEAVSAF 3918
Score = 42.0 bits (97), Expect = 0.012
Identities = 96/500 (19%), Positives = 145/500 (29%), Gaps = 78/500 (15%)
Query: 2397 SHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSG 2456
S R+ + G+ L D +GY+++ + E Q G P +S
Sbjct: 3440 SSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKP----------SSLSMA 3489
Query: 2457 PGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQP-------PRKKSHRVSGKE 2509
R R +P P PA PL P C P + H G
Sbjct: 3490 HSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPR 3549
Query: 2510 RPNHSRG-----DPSHVTQPP----------------PAQGSKEVLRAPG----SPHSQQ 2544
+ R D SH P + R G S SQ+
Sbjct: 3550 AHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQK 3609
Query: 2545 LHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSN 2604
P + H+ D + P P H E R G R S H+ +
Sbjct: 3610 RGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRHGDHGRH-----SGRHTGEEPG 3663
Query: 2605 KKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYA--ASPSHCLSVEGGPEADGE 2662
++ K R L P S + + P S A + PS S +D +
Sbjct: 3664 RRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHA-SDSK 3722
Query: 2663 QPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGA 2722
+ R A GP ++ AE + G A P + ++ A QP Q+
Sbjct: 3723 KGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQ 3782
Query: 2723 SARGFWGPRE--TKAL-------------------------GVCKESGSEPAEDSSRAHS 2755
G P++ T+A G +G +PA +
Sbjct: 3783 QGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQT 3842
Query: 2756 RSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASG 2815
+G + P P PA + G P P Q G G + G
Sbjct: 3843 NGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPG 3902
Query: 2816 SSAKDPPSLFDDEVSFSQLF 2835
+A+ L + +F + F
Sbjct: 3903 GAAEQAGKLTEAVSAFGKKF 3922
Score = 41.6 bits (96), Expect = 0.016
Identities = 76/308 (24%), Positives = 105/308 (34%), Gaps = 79/308 (25%)
Query: 407 PGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG 466
P A + G+ S GP A P PA LP+ Y T P P + RS
Sbjct: 1363 PSSASKEIGMPFSQGPGTPATTAVAPCPAGLPR-------GYMT-PASPAGSERS----- 1409
Query: 467 QPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAG-GPEWQGGSQGALGTAG 525
PSP TA H P A G + + Q G A
Sbjct: 1410 -PSPSS-----------------TAHSYGHS-------PTTANYGSQTEDLPQAPSGLAA 1444
Query: 526 KTPGPREKLPAVRSSQGGSP---ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPR 582
REK + +GG+P ++Y + P P + P SP +P PR
Sbjct: 1445 AGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSP-----SSPSESPTFSPGKMGPR 1499
Query: 583 VVGASPSESPLPSPATNTAGST-CSSLSPM----SSSPANPSS-----EESQLPGP---- 628
+++P P+PA++ S + SPM + +P PS+ +ES P
Sbjct: 1500 ATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
Query: 629 ------------LGPSAFFHP---PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFP- 672
+ SA P PT Q T + PP + PEP FP
Sbjct: 1560 TLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS--VSQLPPEPPGPPGFPR 1617
Query: 673 ADGLGAEG 680
GA+G
Sbjct: 1618 VPSAGADG 1625
Score = 40.8 bits (94), Expect = 0.027
Identities = 53/187 (28%), Positives = 72/187 (38%), Gaps = 35/187 (18%)
Query: 3683 LARGTENGMKP---ATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAK 3739
L G +G P A P PGP G G+ +P + GG Q PA+G +S TA P
Sbjct: 7 LEGGAGDGPLPPGGAGPGPGPGP---GPGAGKPPSAPAGGGQ-LPAAGAARS-TAVPPVP 61
Query: 3740 PSFPSRSPAP------ERL-------------PARAQAKSCTKG---PREAGEQGPHGSL 3777
P P P RL P QA + T G PRE QGP
Sbjct: 62 GPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGP---A 118
Query: 3778 GPKEKGESSTKRKKGQVPGPARSESVG-SFGRAPSAPDKPPR-TPRKQATPSRVLPTKPK 3835
G + G T + + RS SV G P++P P+ P +T + T
Sbjct: 119 GQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDL 178
Query: 3836 PNSQNKP 3842
++ ++P
Sbjct: 179 TSTPSQP 185
Score = 40.8 bits (94), Expect = 0.027
Identities = 70/281 (24%), Positives = 98/281 (34%), Gaps = 30/281 (10%)
Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELP 61
P PRG P + SS H ++T + G A A
Sbjct: 1390 PAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAA 1449
Query: 62 EAQPRQARDGE---LKPPSLRGQAPSSTPGKRGSPQTP--PGRSPLQAPSRLAGRAEGSP 116
+P A DGE +P SS+P P +P P SP +P ++ RA
Sbjct: 1450 REKPLSASDGEGGTPQPSRAYSYFASSSP-----PLSPSSPSESPTFSPGKMGPRATAE- 1503
Query: 117 PQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176
S P+ + P+ A P QG T P RP PR Q +++
Sbjct: 1504 ---------FSTQTPSPAPASDMPRSPGAPTPSPMVAQG--TQTPHRPSTPRLVWQESSQ 1552
Query: 177 ELGFH-RCFQEPPSSFTSTNYTSPSATPR-PPAPGPPQSRGTSPLQPGSYPEY--QASGA 232
E F SS T + S S +P P P + G S P S + + G
Sbjct: 1553 EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGP 1612
Query: 233 DSWP--PAAENSFPGA--NFGVPPAEPEPIPKGSRPGGSPR 269
+P P+A P A +G PAE + + S G+ R
Sbjct: 1613 PGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSR 1653
Score = 40.8 bits (94), Expect = 0.027
Identities = 42/146 (28%), Positives = 62/146 (42%), Gaps = 23/146 (15%)
Query: 3671 PRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQ 3730
P++A+ + ++ T G PA +SQ +G P+PG T G PQPA
Sbjct: 3790 PQQALTQARLQQQSQPTTRGSAPA--------ASQPAGKPQPGPSTATG--PQPAGPPRA 3839
Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKSCTK-GPREAGEQG-PHGSLGPKEKGESSTK 3788
+T + P + AP+ PA + K G R G G P G P GES
Sbjct: 3840 EQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ--PGADGESVFS 3897
Query: 3789 RKKGQVPGPAR------SESVGSFGR 3808
+ +PG A +E+V +FG+
Sbjct: 3898 K---ILPGGAAEQAGKLTEAVSAFGK 3920
Score = 40.0 bits (92), Expect = 0.046
Identities = 108/444 (24%), Positives = 139/444 (31%), Gaps = 105/444 (23%)
Query: 211 PQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPG-------ANFGVPPAEPEPIPKGSR 263
P + PL PG+ P A+ P + +S G +P+ S
Sbjct: 1300 PMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSS 1359
Query: 264 PGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPA 323
P SP S + P G T PA A G P+G PA
Sbjct: 1360 P-ASPSSASKEIGMPFSQGPGT---PATTAVAPCPAG-------LPRGYMT-------PA 1401
Query: 324 YPLPTQPAPSP---LPCYQGQPGGLNRHS---DLSGALSSPGAAHSAPRPFSDSLHKSLT 377
P ++ +PSP Y P N S DL A S AA A R
Sbjct: 1402 SPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAR----------- 1450
Query: 378 KILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARL 437
E+P SA DG G T PQ P +AY + P P + +P P ++
Sbjct: 1451 ----EKPLSASDGEGGT-------PQ---PSRAYSYFASSSPPLSPSSPSESPTFSPGKM 1496
Query: 438 PQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQS--APLPWPQVLPTARPSP 495
GP A F PSP +P+S AP P P V + +P
Sbjct: 1497 ----------------GPRATAE--FSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQ-TP 1537
Query: 496 H--------GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547
H E PF SQ + A + P + S P
Sbjct: 1538 HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSP------LCSPTETQPTT 1591
Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSS 607
Y+ T P V+Q P G P P GA + PL + S
Sbjct: 1592 HGYSQTTPP-------SVSQLPPEPPGPPGFPRVPSAGA---DGPLALYGWGALPAENIS 1641
Query: 608 LSPMSSSPANPSSEESQLPGPLGP 631
L +SS P E PGP P
Sbjct: 1642 LCRISSVPGTSRVE----PGPRTP 1661
Score = 40.0 bits (92), Expect = 0.046
Identities = 51/242 (21%), Positives = 77/242 (31%), Gaps = 13/242 (5%)
Query: 3593 SGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQS-- 3650
S K G GR + H E+ + + H G H ++ PA +
Sbjct: 3641 SAKEHRHGDHGRHSGRHTGEE----PGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQ 3696
Query: 3651 ----SSKDRSAASTPSKALKFPVHPRKAVGSL--APGELARGTENGMKPATPKAKPGPSS 3704
SS + S S S A +K P L E +P + P
Sbjct: 3697 PGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGP 3756
Query: 3705 QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG 3764
Q S SP G + QP + Q Q P + + + P +
Sbjct: 3757 QQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQ 3816
Query: 3765 PREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824
P + GP + GP+ G ++ G G A++ G +A AP P + A
Sbjct: 3817 PAGKPQPGPSTATGPQPAGPPRAEQTNGS-KGTAKAPQQGRAPQAQPAPGPGPAGVKAGA 3875
Query: 3825 TP 3826
P
Sbjct: 3876 RP 3877
Score = 39.3 bits (90), Expect = 0.078
Identities = 106/447 (23%), Positives = 145/447 (32%), Gaps = 97/447 (21%)
Query: 5 RPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAG----------GQ 54
RP G P P GD P Q SS P + P K RE G
Sbjct: 3515 RPAGGPLPP-GGDTCP-QFCSSHSMPDVQEHVKDGPRAHAYK--REEGYILDDSHCVVSD 3570
Query: 55 AQAMELPEAQ------PRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRL 108
++A L + + PR AR + G A SS+ KRG P+R
Sbjct: 3571 SEAYHLGQEETDWFDKPRDARSDRFRHHG--GHAVSSSSQKRG-------------PARH 3615
Query: 109 AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168
+ PP+ + DE A + D + G PG R
Sbjct: 3616 SYHDYDEPPEEGLW---------PHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPG--R 3664
Query: 169 TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228
A+P A +LG H + ++ PS+ P P G P P S Q
Sbjct: 3665 RAAKPHARDLGRHE----------ARPHSQPSSAPAMPKKGQPG-------YPSSAEYSQ 3707
Query: 229 ASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF 288
S A S A +S G+ + P + + P P+ L G P
Sbjct: 3708 PSRASSAYHHASDSKKGSRQA--HSGPAALQSKAEPQAQPQ----------LQGRQAAPG 3755
Query: 289 PADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348
P + P A QPQ ++ +G P TQ L +
Sbjct: 3756 PQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQ-------------ARLQQQ 3802
Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPG 408
S + S+P A+ A +P + T P PP A+ GS + PQ+
Sbjct: 3803 SQPTTRGSAPAASQPAGKPQPGP--STATGPQPAGPPRAEQTNGSK--GTAKAPQQGRAP 3858
Query: 409 QAYRASGVDTSPGPPDTELAA-PGPPP 434
QA A G PGP + A PG P
Sbjct: 3859 QAQPAPG----PGPAGVKAGARPGGTP 3881
Score = 38.9 bits (89), Expect = 0.10
Identities = 58/234 (24%), Positives = 80/234 (34%), Gaps = 30/234 (12%)
Query: 422 PPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLA---ATRSMFFNGQPSPGQRLCLPQ 478
P +AP P P P++A Y P A A+ S + Q G +
Sbjct: 3681 PHSQPSSAPAMPKKGQPGY--PSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSK 3738
Query: 479 SAPLPWPQVLPT-ARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAV 537
+ P PQ+ A P P + S P+G Q +Q G P P++ L
Sbjct: 3739 AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQP-PQQALTQA 3797
Query: 538 RSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA 597
R Q +QP G A P G P P G P+ P A
Sbjct: 3798 RLQQQ---------------SQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG---PPRA 3839
Query: 598 TNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSP 651
T GS ++ +P P ++ + PGP G A P P G+P P
Sbjct: 3840 EQTNGSKGTAKAPQQGRA--PQAQPAPGPGPAGVKAGARPGGTP---GAPAGQP 3888
Score = 38.1 bits (87), Expect = 0.17
Identities = 133/590 (22%), Positives = 196/590 (33%), Gaps = 155/590 (26%)
Query: 628 PLGPSAF----FHPPTHPQETGSPFPSPE--PPHSLPTHYQPE--PAKAFP----FPAD- 674
P GP+AF F PP GS P+ P H PT+ P PA AFP +PA+
Sbjct: 3045 PSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEP 3104
Query: 675 GLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCR 734
GL + AF+ P H + P PT +L D L R
Sbjct: 3105 GLPNQQAFR-----PTGHYAGQT-------------PMPTTQSTLFPVPADSRAPLQKPR 3146
Query: 735 QCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHA 794
Q +SLA D Q+ P + + P P A + S++
Sbjct: 3147 Q-----TSLA-----------------DLEQKVPTNYEVIASPVVPMSSAPSET---SYS 3181
Query: 795 KTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASD---LDMEDDAKLDSLITEALNGM 851
+ +G Q + + P R G S++ +P P SD +E + + ++ + ++ +
Sbjct: 3182 GPAVSSGYEQGKVPEVP-RAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISEL 3240
Query: 852 EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911
S + DS + EP GP SSG P K P P P P
Sbjct: 3241 TKDSTSTAPDSQRL------EPLGP--GSSGRPGKE-----------PGEPGVLDGPTLP 3281
Query: 912 RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971
C ARG ++ P RGK GG S G
Sbjct: 3282 -----CCYARGEEESEEDSYDP-------------RGK-----------GGHLRSMESNG 3312
Query: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLP 1031
RP G+ R PG P A A RS R++
Sbjct: 3313 -------RPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQ-- 3363
Query: 1032 PRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEED--EQPPPRGPGFRGRRGR 1089
G E Q+ ++ + A + E D PPP RGR
Sbjct: 3364 ---------------GME------QKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGR 3402
Query: 1090 GEKRKEVELTQGPRED--EPQKPRKAARQEA-------GGDGAPANPEEPGGSR-PGPGR 1139
+ + E+T G +++ E QK + ++A GG P G +
Sbjct: 3403 ---KFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDF 3459
Query: 1140 SPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRP 1189
S +G R E ++ GPK + + ++ P ++ SEE P
Sbjct: 3460 SGWGKGYEREREAVERLQKAGPKPSSLSMAHSR--VRPPMRSQASEEESP 3507
Score = 38.1 bits (87), Expect = 0.17
Identities = 60/219 (27%), Positives = 76/219 (34%), Gaps = 36/219 (16%)
Query: 328 TQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDS------LHKSLTKILP 381
+QP+ +P +GQPG + S S P A SA SDS H +
Sbjct: 3683 SQPSSAPAMPKKGQPGYPS-----SAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
Query: 382 ERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPG----PPP--- 434
+ P AQ L + P Q P SG + P T+ G PP
Sbjct: 3738 KAEPQAQPQLQGRQAAPGP-QQSQSPSSRQIPSGAASRQ--PQTQQQQQGLGLQPPQQAL 3794
Query: 435 --ARLPQLWDPT--------AAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPW 484
ARL Q PT + P P GP AT G P Q +A P
Sbjct: 3795 TQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPA-GPPRAEQTNGSKGTAKAPQ 3853
Query: 485 ----PQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQG 519
PQ P P P G++ +R G P Q G+ G
Sbjct: 3854 QGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADG 3892
Score = 37.7 bits (86), Expect = 0.23
Identities = 41/161 (25%), Positives = 58/161 (36%), Gaps = 24/161 (14%)
Query: 566 AQPQVSPH--GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623
A+PQ P G + P P+ SPS +PS A + T + P + ++
Sbjct: 3739 AEPQAQPQLQGRQAAPGPQQ-SQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQA 3797
Query: 624 QLPGPLGPSAFFHPPTHPQETGSPFPSPE---------PPHSLPTHYQPEPAKAFPFPAD 674
+L P+ P Q G P P P PP + T+ AKA P
Sbjct: 3798 RLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA---PQQ 3854
Query: 675 GLGAEGAFQCLEETPFPHEGPEVGRGGLQ--GFPRAPPPYP 713
G + + P P GP + G + G P AP P
Sbjct: 3855 G-------RAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
Score = 37.7 bits (86), Expect = 0.23
Identities = 38/165 (23%), Positives = 54/165 (32%), Gaps = 18/165 (10%)
Query: 12 PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDG 71
P LQ RQ A P P + + + Q ++ P+ QAR
Sbjct: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQ 3800
Query: 72 ELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKP 131
+ P+ RG AP++ + P P PS G PP+ + +T
Sbjct: 3801 QQSQPTTRGSAPAA---------SQPAGKPQPGPSTATGPQPAGPPR-------AEQTNG 3844
Query: 132 TLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176
+ Q A Q P G A RPG T PA +
Sbjct: 3845 SKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPG--GTPGAPAGQ 3887
Score = 37.4 bits (85), Expect = 0.30
Identities = 31/103 (30%), Positives = 42/103 (40%), Gaps = 13/103 (12%)
Query: 79 RGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSP-PQRYILGIASSRTKPTLDETP 137
R APS P + PP P+ A +A G+ P R + + ++R +P TP
Sbjct: 2260 RYPAPSRFPI---ASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTP 2316
Query: 138 EN---------PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEA 171
P A Q P D G G+GA RPG + EA
Sbjct: 2317 AAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEA 2359
Score = 37.0 bits (84), Expect = 0.39
Identities = 53/229 (23%), Positives = 77/229 (33%), Gaps = 40/229 (17%)
Query: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL 2040
P G ASP + P+ + S + + E P PS +
Sbjct: 1390 PAGLPRGYMTPASPAGSERSPSPSSTA-HSYGHSPTTANYGSQTEDLPQAPSGLAAAGRA 1448
Query: 2041 ALTAAHSRSGSEGRTPE--------RASSPGLN------KPLLATGDSPAPSVGDLAACA 2086
A S S EG TP+ +SSP L+ P + G + + +
Sbjct: 1449 AREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQT 1508
Query: 2087 PSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPS-----------------CR 2129
PSP A+ MP S G P SP AQG P++P
Sbjct: 1509 PSPAPASDMPRSPGA-----PTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLAS 1563
Query: 2130 DPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP 2178
D +++ S + +PL Q TT S PPS++ P +P
Sbjct: 1564 DASSQTRMVHASASTSPLCSPTETQPTTH---GYSQTTPPSVSQLPPEP 1609
Score = 37.0 bits (84), Expect = 0.39
Identities = 65/258 (25%), Positives = 83/258 (32%), Gaps = 51/258 (19%)
Query: 1751 EPGT-ADQPH-RGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATW--PFGASPS-HAAQG 1805
EPG A +PH R EA AP + +G P A + P AS + H A
Sbjct: 3661 EPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASD 3720
Query: 1806 HSAGRAGGHLHPTA--------GRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVS 1857
G H P A +P +G + AP G +P R+ +PS A
Sbjct: 3721 SKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAP-GPQQSQSPSSRQ-----IPSGAASR 3774
Query: 1858 NTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTV 1917
++ Q L PP + L + QS P T
Sbjct: 3775 QPQTQQQQQGLGLQPPQQ-----------------ALTQARLQQQSQP----------TT 3807
Query: 1918 EGGKVACGPAQGSPG-GVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPE 1976
G A G P G T P AG + +G G K QG A Q QP
Sbjct: 3808 RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKG----TAKAPQQGRAPQAQPA 3863
Query: 1977 NGVSPGGTDNHASVNASP 1994
G P G A +P
Sbjct: 3864 PGPGPAGVKAGARPGGTP 3881
Score = 36.2 bits (82), Expect = 0.66
Identities = 54/200 (27%), Positives = 75/200 (37%), Gaps = 30/200 (15%)
Query: 869 ADEEPSGPRGPSSGHP-LKSKAGVTPESKAPPPLPA--ATPDPQTPR-PGDRGCP---AR 921
A + G R SG L+SKA E +A P L A P PQ + P R P A
Sbjct: 3718 ASDSKKGSRQAHSGPAALQSKA----EPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS 3773
Query: 922 GRPKTRS----LGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASG 977
+P+T+ LGL P P Q Q R +Q S GS A
Sbjct: 3774 RQPQTQQQQQGLGLQP-----PQQALTQARLQQ--------QSQPTTRGSAPAASQPAGK 3820
Query: 978 LRPRRNDGLGERP--PPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKD 1035
+P + G +P PPR + ++A R P+A P + + P
Sbjct: 3821 PQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT 3880
Query: 1036 PRKRKARGGAWGKELILKIV 1055
P + GA G+ + KI+
Sbjct: 3881 PGAPAGQPGADGESVFSKIL 3900
Score = 34.3 bits (77), Expect = 2.5
Identities = 42/176 (23%), Positives = 58/176 (32%), Gaps = 27/176 (15%)
Query: 321 GPAYPLPTQPAPSPLPC---YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLT 377
G A + +P P P P ++ P L H AL H+ + ++T
Sbjct: 1822 GTAQSIGLKPGPVPEPGAEPHRATPAELRSH-----ALPGARKPHTVVVQMGEGTAGTVT 1876
Query: 378 KILPERPPSAQDGLGSTRGPPSSLP----QRHFPGQAYRASGVDTSPGPPDTELAAPGPP 433
+LPE P A D G P S L P + +P P+ +A PP
Sbjct: 1877 TLLPEEPAGALDLTGMR--PESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPP 1934
Query: 434 PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489
+ P P PP + G PG P P+PQ LP
Sbjct: 1935 GQSSSPFYGPRDPEPPEPP--------TYRAQGVVGPG-----PHEEQRPYPQGLP 1977
Score = 33.9 bits (76), Expect = 3.3
Identities = 120/515 (23%), Positives = 174/515 (33%), Gaps = 137/515 (26%)
Query: 3452 PGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCS-------EVAPSTTKGWPETL--ERP 3502
PG P PG P P G+LP S A S P+T+ ER
Sbjct: 404 PGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERA 463
Query: 3503 VDPVTHPIR--GCELPSNHQECPPPSL--------SPFPAALADGRG---DCALDGALER 3549
+ P+ G + P+N+ C L +P P + +C LE
Sbjct: 464 ICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEG 523
Query: 3550 PENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGR-CAPD 3608
E +P P P QQ P+GA G +PL K++ P G+ P
Sbjct: 524 SLGEPTP-LPPPTSQQP-PVGAPHRASGT---------SPL----KQKGPQGLGQPSGPL 568
Query: 3609 HFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP 3668
+ L K +S + S+ P+ + A++P+ SS +++ P+KA P
Sbjct: 569 PAKASPLSTK-----ASPLPSKASPQAKPLR--ASEPSKTPSSVQEKK-TRVPTKAEPMP 620
Query: 3669 VHPRKAVGSLAPGELARGTENGMKPATPKAKPGP----------------SSQGSGSPRP 3712
P + + A ++ G +PATP K P S S SP+
Sbjct: 621 KPPPETTPTPATPKVKSGVRRA-EPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQS 679
Query: 3713 GTKTGGGSQ------------PQPASGQLQSETATTPAKPSFPSR------SPAP----E 3750
+ TG S Q QL S T P PS PS S P +
Sbjct: 680 LSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPS-PSEIHKVGSSMRPLLQAQ 738
Query: 3751 RLPARAQAKSCTKGPREAGEQGPHG-SLGPK------------EKGESST--KRKKGQVP 3795
L ++K + G E +Q PH S+ P+ E+ E S +R++ Q
Sbjct: 739 GLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQD 798
Query: 3796 GPARSESVGS------------FGRAPSAPDKPPRTP--------RKQ------------ 3823
S+ GS G +P P P R R+Q
Sbjct: 799 TAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLE 858
Query: 3824 ----ATPSRVLPTKPKPNSQNKPRPPPSEQRKAEP 3854
AT R L +PRP PS++ A P
Sbjct: 859 EDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALP 893
Score = 33.1 bits (74), Expect = 5.6
Identities = 56/233 (24%), Positives = 79/233 (33%), Gaps = 47/233 (20%)
Query: 1104 EDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKC 1163
ED PQ P A A G A E+P + G G +PQ PSR+ A++
Sbjct: 1433 EDLPQAPSGLA---AAGRAA---REKPLSASDGEGGTPQ---PSRAYSYFASS------- 1476
Query: 1164 ADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAA 1223
P ++P P + PT + R + +F + ++P A
Sbjct: 1477 --SPPLSPSSPSESPTFSPGKMGPRATAEF----------------------STQTPSPA 1512
Query: 1224 CAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283
A +M SPG P P T TP + S P + L +Q
Sbjct: 1513 PASDMPRSPG--APTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTR 1570
Query: 1284 VSH-NSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDP 1335
+ H ++ P P E S T P S L + P GF R P
Sbjct: 1571 MVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPG----PPGFPRVP 1619
Score = 33.1 bits (74), Expect = 5.6
Identities = 52/219 (23%), Positives = 81/219 (36%), Gaps = 22/219 (10%)
Query: 967 SGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSR 1026
+G G RA+ +P D LG R RP + AP P P +A + +R+S
Sbjct: 3658 TGEEPGRRAA--KPHARD-LG-RHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASS 3713
Query: 1027 RRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP----PRGPG 1082
R+A G + + Q + +L+ A ++ + P P G
Sbjct: 3714 AYHHASDSKKGSRQAHSGPAALQSKAE-PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAA 3772
Query: 1083 FRG------RRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSR-- 1134
R ++G G + + LTQ + + Q R A PA +PG S
Sbjct: 3773 SRQPQTQQQQQGLGLQPPQQALTQARLQQQSQP---TTRGSAPAASQPAGKPQPGPSTAT 3829
Query: 1135 -PGPGRSPQARGPSRSLETGAAAREG-GPKCADRPSVAP 1171
P P P+A + S T A ++G P+ P P
Sbjct: 3830 GPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGP 3868
Score = 32.7 bits (73), Expect = 7.3
Identities = 26/110 (23%), Positives = 38/110 (34%), Gaps = 1/110 (0%)
Query: 4 ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEA 63
+ P P+ QP+ G QPP + T A + G A A P
Sbjct: 3760 QSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAG 3819
Query: 64 QPRQARDGELKPPSLRGQAPSSTPGKRGSPQTP-PGRSPLQAPSRLAGRA 112
+P+ P T G +G+ + P GR+P P+ G A
Sbjct: 3820 KPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPA 3869
Score = 32.3 bits (72), Expect = 9.5
Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 12/88 (13%)
Query: 3215 RSAGKAAGSP-GDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGS 3273
R + AA P G P Q G + P PRA T + A P A A
Sbjct: 3808 RGSAPAASQPAGKP--QPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPG 3865
Query: 3274 PGP--------PRTTP-SPSPDPWAGGE 3292
PGP P TP +P+ P A GE
Sbjct: 3866 PGPAGVKAGARPGGTPGAPAGQPGADGE 3893
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 98.6 bits (244), Expect = 1e-19
Identities = 179/738 (24%), Positives = 246/738 (33%), Gaps = 131/738 (17%)
Query: 10 PPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAME---------L 60
P G L PR PG P PP TPA GA A G+ E +
Sbjct: 17 PAARAPGLLTPRP----PGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120
PE+ PR P+ + P+S G+R P P+ +P R +G P +
Sbjct: 71 PESAPRAG-------PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123
Query: 121 ILGIASSRT--KPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEEL 178
L I++ T + E P+ L A + P PGT +P ++ A E+
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAM----ARRSRAAGTEV 178
Query: 179 GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPA 238
G R +PSA PRPP GP +S ++ + + S A P+
Sbjct: 179 GLPR--------------PAPSARPRPPTEGPRKSVSSA----SEHSTTEPSPAARRRPS 220
Query: 239 AENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP------FPADV 292
A + P+ +R G S RG P H + KP P V
Sbjct: 221 AGGGLQRPASRSLSSSATPLSSPARSGPSARGT----PRAPAHPSQPKPKGLQALRPPQV 276
Query: 293 AGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-----LPTQPA--PSPLPCYQGQPGGL 345
P + A P + P+ P LP+ PA PS G P
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336
Query: 346 NRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS-AQDGLGSTRGPPSSLPQR 404
HS L SP + A P P+ PP+ A L + PP+S P
Sbjct: 337 ATHS----FLPSPPLSPLATPP-------------PQAPPALALPPLQAPPSPPASPPLS 379
Query: 405 HF---PGQAYRASGVDT-----SPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPL 456
QA A V SP PP + AP PPA P +P TPP
Sbjct: 380 PLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPFSPPA------SPPVSPSATPPSQAP 432
Query: 457 AATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGG 516
+ + PSP P S P+ P+A P P L+ P P Q
Sbjct: 433 PSLAAPPLQVPPSP------PASPPMS-----PSATPPPQAPPPLAAPPLQLAKPPPQAP 481
Query: 517 SQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG-VAQPQVSPHGT 575
A P P P + + P A P+ + Q SP +
Sbjct: 482 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 541
Query: 576 PSLPPPR----------------VVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPS 619
P+L PR + +P P PS + ++ S SS+ + P
Sbjct: 542 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 601
Query: 620 SEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPF-PADGLGA 678
GP G +A PP P P + P ++ P P+ PA G G+
Sbjct: 602 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP-APPLAFRGAPGAPLPWPPATGPGS 660
Query: 679 EGAFQCLEETPFPHEGPE 696
+ ET EGPE
Sbjct: 661 ADGLCTIYET----EGPE 674
Score = 97.1 bits (240), Expect = 3e-19
Identities = 155/607 (25%), Positives = 205/607 (33%), Gaps = 123/607 (20%)
Query: 8 GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATR-TTKGAREAGGQAQAMELPEAQPR 66
G P P M + R + G P P P T K A + P A+ R
Sbjct: 161 GTPSPAMAR--RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218
Query: 67 QARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIAS 126
+ G L+ P+ R + S+TP + P R +AP+ P Q G+ +
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH--------PSQPKPKGLQA 270
Query: 127 SR----TKPTLDETPENPQLEAAQL--PEVDTPQGPGTGAPLR--PGLPRTEAQPAAEEL 178
R T P D P L ++ L P P P L+ P P T A L
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330
Query: 179 G------FHRCFQEPP-SSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASG 231
G H PP S + +P A PP PP + PL P + P QA
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390
Query: 232 A---------DSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVS---FQFP--F 277
A S PP+ P + PPA P P + P +P ++ Q P
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFS----PPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446
Query: 278 PALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPC 337
PA S P A PL A PQ A+ T P LP+ PA P
Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA---PPALATPPLQALPSPPASFP--- 500
Query: 338 YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGP 397
GQ + S + S P + + P P + + + +P PP A L + R P
Sbjct: 501 --GQ-------APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP-ASPTLQAPRRP 550
Query: 398 PSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQ--LWDPTAAPYPT----- 450
P+ P G + +PGPP PPP+R P L P A + +
Sbjct: 551 PTPGPDTSVSGPRLTLA---LAPGPP--------PPPSRSPSSTLSGPDLAGHSSSATST 599
Query: 451 -------------------PPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTA 491
PP LAA ++ P+P APLPWP
Sbjct: 600 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP------ 653
Query: 492 RPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYN 551
PA GP GS L T +T GP PA + G P+ T
Sbjct: 654 ---------------PATGP----GSADGLCTIYETEGPESATPAPGALDPG-PSPGTSG 693
Query: 552 GMTDPGA 558
G GA
Sbjct: 694 GKAAAGA 700
Score = 91.7 bits (226), Expect = 1e-17
Identities = 152/575 (26%), Positives = 198/575 (34%), Gaps = 119/575 (20%)
Query: 202 TPRPP-APGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIP- 259
TPRPP +P PP P+ P + A+GA P AE + +P + P P
Sbjct: 26 TPRPPGSPRPPP-----PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 260 KGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTN---GPLVFAFHQPQGAWPEE 316
+ SRP S RG A +T P P G A GPL + EE
Sbjct: 81 RTSRPPASGRGER------APPAKNTSPGPVSSPGRASGTTRPGPLG---QKGLRISAEE 131
Query: 317 AVGTGPAYPLPTQPAPS---------PLPCYQGQPG-GLNRHSDLSGA-LSSPGAAHSA- 364
V G A P + A S P P G P + R S +G + P A SA
Sbjct: 132 TVARGKATEAPKRSALSAGARRDTSGPTP---GTPSPAMARRSRAAGTEVGLPRPAPSAR 188
Query: 365 PRPFSDSLHKSLTKI----------LPERPPSAQDGLG-------STRGPPSSLPQRHFP 407
PRP ++ KS++ R PSA GL S+ P S P R P
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248
Query: 408 GQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY---PTPPGGPLAATRSMFF 464
A G +P P P P L L P P P GPL+
Sbjct: 249 S----ARGTPRAPAHPSQ------PKPKGLQALRPPQVTPPRKDAAPALGPLS------- 291
Query: 465 NGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG----GSQGA 520
S+PL P P+A PSP L LP P P Q GS
Sbjct: 292 --------------SSPLATPS--PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335
Query: 521 LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP 580
T P P L + + +P + P + P A P +SP TPS
Sbjct: 336 QATHSFLPSP--PLSPLATPPPQAPPALALPPLQAPPSPP-----ASPPLSPLATPSPQA 388
Query: 581 PRVVG--------ASPSESPLPSPATNTAGSTCS-SLSPMSSSPANPSSEESQLPG---- 627
P + + P P+ +P + A S S +P S +P + ++ Q+P
Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448
Query: 628 --PLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCL 685
P+ PSA P P P +PP P P +A P P + F
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508
Query: 686 EETPF------PHEGPEVGRGGLQGFPRAPPPYPT 714
P P + P V L P +PP PT
Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Score = 75.5 bits (184), Expect = 1e-12
Identities = 161/648 (24%), Positives = 212/648 (32%), Gaps = 112/648 (17%)
Query: 875 GPRGPSSGHPLKSKAG-----VTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSL 929
G G PL +AG PES AP P T P G+R PA K S
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPES-APRAGPTRTSRPPASGRGERAPPA----KNTSP 102
Query: 930 GLAPTEADAPSQGRQQRRG-KQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGE 988
G + A R G K L++ ++ + G A + A R G
Sbjct: 103 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162
Query: 989 RPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGK 1048
P RR R A G+ LP S+R R PP + PRK +
Sbjct: 163 PSPAMARRSR--AAGTE----------VGLPRPAPSARPR--PPTEGPRKSVSSAS---- 204
Query: 1049 ELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQ 1108
E+ S + P G G + R L+
Sbjct: 205 --------------EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS--------- 241
Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPS 1168
P ++ G APA+P +P R PQ P + P PS
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 1169 VAPK-------DPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPP 1221
P L P T S+ T SL P + + S P S T ++PP
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQAT-TSLGSP-TLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 1222 AACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLA---NTAPHGSSPTPGVGSLLGGPG 1278
A + A P P PP S T +P+ +LA AP P+P V
Sbjct: 360 ALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-------- 409
Query: 1279 GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGV 1338
QAP S PPA P ++P A P S A PS+ + + PA P
Sbjct: 410 --QAPFS-----PPASPP---VSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSAT 457
Query: 1339 PVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLE 1398
P + P P ++P +L P P A +PPAS G+ S
Sbjct: 458 P-PPQAPPPLAAPPLQLAKPPPQAPPALAT---PPLQALPSPPASF-----PGQAPFSPS 508
Query: 1399 PQLPRSPPGTAETEPGRAASPPTLE---SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFA 1455
LP SP T + + P L+ S P L R PP G ++ L A
Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR-RPPTPGPDTSVSGPRLTLA 567
Query: 1456 CADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPE 1503
A P PP PS SP PDL+G + + P E
Sbjct: 568 LA-------PGPPPPPS------RSPSSTLSGPDLAGHSSSATSTPEE 602
Score = 73.9 bits (180), Expect = 3e-12
Identities = 165/692 (23%), Positives = 225/692 (32%), Gaps = 98/692 (14%)
Query: 1761 GAPAPEAF--GSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHP- 1817
GA PE+ P P + +G+ APP T P S S GRA G P
Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVS--------SPGRASGTTRPG 118
Query: 1818 TAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIR-- 1875
G+ G + T R A + + A + P+ + PA++ R
Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSA----LSAGARRDTSGPTPGTPSPAMARRSRAA 174
Query: 1876 --QLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACG-PAQGSPG 1932
++ LP P + P + P + S E T E A P+ G G
Sbjct: 175 GTEVGLPRPAPSARP---------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG--G 223
Query: 1933 GVQVTTLPAVAGHQLGLEADGHWGLLGQ------AEKTQGQGTANQLQPENGVSPGGTDN 1986
G+Q +++ L + G + A +Q + Q V+P D
Sbjct: 224 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 283
Query: 1987 HASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL-ALTAA 2045
++ + L P+ A A SLQ P +PPS SL L A
Sbjct: 284 APALGPLSSSPLATPSPSAP-----PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338
Query: 2046 HSRSGSEG----RTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGP 2101
HS S TP + P L P L SP S PSP + + L
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398
Query: 2102 LPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGA 2161
P P + P +A P SPS P LA P P + A
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSA 456
Query: 2162 EDSPVAPPSLTTSPC-------DPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSG 2214
P APP L P ALA LQ SP P+S+P G
Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP---PASFP------------G 501
Query: 2215 DTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP--SVAVRATGLSSTPTGDEAQAG 2272
P + +P ++P +P L SP S ++A TP D + +G
Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561
Query: 2273 RGL-----PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARL-GHREGQAVTAVPTEPPT 2326
L PGP P +P T GHSS + S L G+ G A + PP
Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621
Query: 2327 LQGA---------GPDSPACLEGEMGTSSKEP--EDPGTPE--------TGRSGATKMPR 2367
+ A GP P G G P PG+ + G AT P
Sbjct: 622 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681
Query: 2368 VTCPSTGLGLGRTTAPSSTASDFQSDSPQSHR 2399
P G A + + S SP+ R
Sbjct: 682 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 713
Score = 71.6 bits (174), Expect = 1e-11
Identities = 198/785 (25%), Positives = 264/785 (33%), Gaps = 130/785 (16%)
Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPS 1168
K AAR A P PG RP P +P A R L GAA G A+R
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAA---LRVL--GAAGAVGRKPLAERAG 63
Query: 1169 VAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAE-ESAPDSTEFTEALRSPPAACAGE 1227
T E+ P + ++ P + E AP + + S P +G
Sbjct: 64 ---------GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGT 114
Query: 1228 MGASP----GLLIPEQPPPSR-HDTGTPKPSGSLANTAPHGSSPTPGVGS--------LL 1274
P GL I + +R T PK S A S PTPG S
Sbjct: 115 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 174
Query: 1275 GGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCD-PAGFNR 1333
G G P PP P + ++ A+ ST P P+ + G PA +
Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSS-ASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 1334 DPLGVPV---AKKGPQPYSSPHSELFLGPKDLAGCFLEELHP---KPSARDAPPA----S 1383
P+ A+ GP +P + G L+ L P P +DA PA S
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQALRPPQVTPPRKDAAPALGPLS 291
Query: 1384 SSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSL-FPDLPVDRF---DPP 1439
SS L A P P +PP + +T P A+PP+ ++SL P L PP
Sbjct: 292 SSPLATPSPSA----PPSPSAPP-SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346
Query: 1440 LYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFP-DLSGGKVLSK 1498
L S A P A A PP + PS P P L SP P+ L
Sbjct: 347 L--SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 1499 TCPP-ERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAP 1557
PP + P A+P + + S A S L+ L++ + AP
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Query: 1558 RELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVA 1617
LA ++L +PP Q AT P
Sbjct: 464 PPLAAPP----LQL---AKPPPQAPPALATPP---------------------------- 488
Query: 1618 TVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKT 1677
+Q P PASF PG A P A + A P+ P+ + S
Sbjct: 489 ----LQALPSP----PASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539
Query: 1678 GLCQAEGDSRPP---QDVCLPEP----SKQPGPQLDAGSLAKCSPDQELSFPK-NKEAAS 1729
+ RPP D + P + PGP SP LS P ++S
Sbjct: 540 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR----SPSSTLSGPDLAGHSSS 595
Query: 1730 SQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPL 1789
+ + + LR GG P + PA + G AP LAF+ GAP
Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP-----APPLAFR--GAPGA 648
Query: 1790 DATWPFGASPSHA--------AQG-HSAGRAGGHLH--PTAGRPGFEGNEFAPAGASSLT 1838
WP P A +G SA A G L P+ G G + A AGASS +
Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 708
Query: 1839 APRGR 1843
+ R
Sbjct: 709 PKQAR 713
Score = 67.0 bits (162), Expect = 3e-10
Identities = 104/390 (26%), Positives = 130/390 (33%), Gaps = 69/390 (17%)
Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-NTPATRTTKGAREAGGQAQAMEL 60
P P PPP L + + P P+ PPL TP+ + A A+ L
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP--------NALAVHL 396
Query: 61 PEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120
+A PPS QAP S P P +P P QAP LA PP
Sbjct: 397 LQAP-------FSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPP--- 444
Query: 121 ILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGF 180
P +P + + P P P PL+ P +A PA
Sbjct: 445 --------------SPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPL 489
Query: 181 HRCFQEPPSSFTSTNYTSPSAT------PRPPAPGPPQSRG---TSPLQPGSYPEYQASG 231
+ PP+SF SPSA+ PP PP P P + P QA
Sbjct: 490 -QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548
Query: 232 ADSWP-PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPA 290
P P S P + P P P P SP + P A H +S P
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPP------PSRSPSS-TLSGPDLAGHSSSATSTPE 601
Query: 291 DVAGHAFTNGPLVFAFHQPQ-----GAWPEEAVGTGPAYPL-----PTQPAPSPLPCYQG 340
++ G + +GP A P A A GPA PL P P P P G
Sbjct: 602 ELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 659
Query: 341 QPGGLNRHSDLSG---ALSSPGAAHSAPRP 367
GL + G A +PGA P P
Sbjct: 660 SADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 64.7 bits (156), Expect = 2e-09
Identities = 118/486 (24%), Positives = 164/486 (33%), Gaps = 94/486 (19%)
Query: 3458 PGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPS 3517
PG RPPP P+ PA L + K P+ I G +P
Sbjct: 30 PGSPRPPP----PVT-----PAALRVLGAAGAVGRK--------PLAERAGGIGGATIPE 72
Query: 3518 NHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGS------PGPLLQQALPLGA 3571
+ P S PA+ GRG+ A P +SPG PGPL Q+ L + A
Sbjct: 73 SAPRAGPTRTSRPPAS---GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129
Query: 3572 SLPRPGARGQDAEGKRAPLVFSGKRR-----APGARG-----------------RCAPDH 3609
ARG+ E + + +G RR PG R AP
Sbjct: 130 E--ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187
Query: 3610 FQEDHLLQKEKEVSSS--HMVSEGGP---RGTFHKGSATKPAGCQSSSKDRSAASTPSKA 3664
K VSS+ H +E P R G +PA +S S + S+P+++
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARS 246
Query: 3665 -------LKFPVHPR----KAVGSLAPGELARGTEN-----GMKPATPKAKPGPSSQGSG 3708
+ P HP K + +L P ++ ++ G ++P A P PS+ S
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 3709 SPRPGTKTGGGSQPQP--------ASGQLQSETATTPAKPSFPSRSPAPERLPARAQAK- 3759
S P +T P S LQ+ + P+ P P +P P+ PA A
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366
Query: 3760 SCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRT 3819
P + P + P+ + + P F S P P T
Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426
Query: 3820 PRKQATPSRVLPTKPKPNSQNKPRPPPSEQR--------KAEPGHTQRKDRLGKAFPQGR 3871
P QA PS P Q P PP S +A P +L K PQ
Sbjct: 427 PPSQAPPSLAAPPL-----QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481
Query: 3872 PLLRPP 3877
P L P
Sbjct: 482 PALATP 487
Score = 64.7 bits (156), Expect = 2e-09
Identities = 94/377 (24%), Positives = 138/377 (36%), Gaps = 53/377 (14%)
Query: 3523 PPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASL--PRPGARG 3580
PPP ++P + G +P E + G G + ++ P RP A G
Sbjct: 35 PPPPVTPAALRVLGAAGAVG-----RKPLAERAGGIGGATIPESAPRAGPTRTSRPPASG 89
Query: 3581 QDAEGKRAPLVFSGKRRAPG---ARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTF 3637
+ G+RAP K +PG + GR A + L QK +S+ V+
Sbjct: 90 R---GERAP---PAKNTSPGPVSSPGR-ASGTTRPGPLGQKGLRISAEETVA-------- 134
Query: 3638 HKGSATK-PAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP 3696
+G AT+ P S+ R S P+ P R++ A GTE G+ P
Sbjct: 135 -RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS--------RAAGTEVGLPRPAP 185
Query: 3697 KAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA--TTPAKPSFPSRSPAPERLPA 3754
A+P P ++G ++P PA+ + S PA S S S P PA
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL-SSSATPLSSPA 244
Query: 3755 RAQAKSCTKGPREAG-EQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAP 3813
R+ GP G + P PK KG + + + P + ++G +P A
Sbjct: 245 RS-------GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297
Query: 3814 DKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPL 3873
P P A PS L T P P P PPS+ + T + P PL
Sbjct: 298 PSPSAPPSPSAPPS--LQTLPSP-----PATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350
Query: 3874 LRPPKRGTAVHGAEPAE 3890
PP + P +
Sbjct: 351 ATPPPQAPPALALPPLQ 367
Score = 61.6 bits (148), Expect = 1e-08
Identities = 132/540 (24%), Positives = 171/540 (31%), Gaps = 79/540 (14%)
Query: 876 PRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQT----PRPGDRGC---------PARG 922
PR P+ G P KS + + S P PAA P RP R PAR
Sbjct: 189 PRPPTEG-PRKSVSSASEHSTTEPS-PAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246
Query: 923 RPKTRSLGLAPTEADAPS-QGRQQRRGKQLKLFRKDLDSG-GAAEGSGSGGGGRASGLRP 980
P R AP P +G Q R Q+ RKD G S ++ P
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 981 RRNDGLGERPPPRPRRPRTQAPGSRADPA--------PRVPRAAALPEETRSSRRRRLPP 1032
L P P P P +QA S P P P + ++ LPP
Sbjct: 307 SAPPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 1033 RKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEK 1092
+ P A L Q N L + + PPP P
Sbjct: 366 LQAPPSPPASPPL--SPLATPSPQAPNALAVHLLQAPFS----PPPSPP----------- 408
Query: 1093 RKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLET 1152
V+ P P P +A A + P P SP A P ++
Sbjct: 409 ---VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA--- 462
Query: 1153 GAAAREGGPKCADRPSVAPKDPLQVPTNTET---SEETRPSLDFPQEAKEPETAEESAPD 1209
P A P K P Q P T P FP +A P + S P
Sbjct: 463 -------PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA--PFSPSASLPM 513
Query: 1210 STEFTEALRSPPAACAGEMG------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHG 1263
S T ++PP A + ASP L P +PP DT P +LA
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573
Query: 1264 SSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISS 1323
P+ S L GP A S ++ P G P +++ P + +
Sbjct: 574 PPPSRSPSSTLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA----- 626
Query: 1324 FGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAG-CFLEELHPKPSARDAPPA 1382
C PA ++R P P+A +G P GP G C + E SA AP A
Sbjct: 627 --CHPAAWSRGP-APPLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGPESATPAPGA 682
Score = 57.8 bits (138), Expect = 2e-07
Identities = 194/790 (24%), Positives = 249/790 (31%), Gaps = 142/790 (17%)
Query: 428 AAPGPPPARLPQLWD--PTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWP 485
AA P AR P L P +P P PP P AA R + G R L + A
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTP-AALRVL---GAAGAVGRKPLAERAGGIGG 67
Query: 486 QVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSP 545
+P + P G SR P A G + P + P SS G +
Sbjct: 68 ATIPESAPRA-GPTRTSRPP--------------ASGRGERAPPAKNTSPGPVSSPGRA- 111
Query: 546 ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA-TNTAGST 604
+G T PG PL G ++S T + +P S L + A +T+G T
Sbjct: 112 -----SGTTRPG--PL--GQKGLRISAEETVARGK---ATEAPKRSALSAGARRDTSGPT 159
Query: 605 CSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPE 664
+ SP + + + E LP P PSA PPT E S HS +P
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRP-APSARPRPPT---EGPRKSVSSASEHSTT---EPS 212
Query: 665 PAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASL 724
PA A G A + L + P P +G PRA P +P+ +L
Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA-PAHPSQPKPKGLQAL 271
Query: 725 DQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPP----GLPSPPAAP 780
V + L++ LA SP P LPSPPA P
Sbjct: 272 RPPQVTPPRKDAAPALGPLSS---------SPLATPSPSAPPSPSAPPSLQTLPSPPATP 322
Query: 781 RVPADAHAG--LLSHAKTFLLAGDAQAEGKDDPLRTG--FLPSLAATPFP---LPASDLD 833
A G L +FL + P LP L A P P P S L
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382
Query: 834 MEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAG--- 890
++L L +P + + F S P PS+ P ++
Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAA 437
Query: 891 ----VTPESKAPPPL-PAATPDPQTP-----------RPGDRGCPARGRPKTRSLGLAPT 934
V P A PP+ P+ATP PQ P +P + PA P ++L P
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP- 496
Query: 935 EADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRP 994
A P Q +A S P L + PP P
Sbjct: 497 -ASFPGQA----------------PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539
Query: 995 RRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELI--- 1051
P QAP R P P + + P T + P P R G +L
Sbjct: 540 ASPTLQAP--RRPPTPGPDTSVSGPRLTLA----LAPGPPPPPSRSPSSTLSGPDLAGHS 593
Query: 1052 LKIVQQKNRLREYDFASESEEDEQPPP-------------RGP----GFRGRRGRGEKRK 1094
LR YD E PPP RGP FRG G
Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG------ 647
Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGA 1154
L P E +G + PG PGP SP G + GA
Sbjct: 648 -APLPWPPATGPGSADGLCTIYET--EGPESATPAPGALDPGP--SPGTSGGKAAAGAGA 702
Query: 1155 AAREGGPKCA 1164
A PK A
Sbjct: 703 GASSRSPKQA 712
Score = 52.0 bits (123), Expect = 1e-05
Identities = 148/596 (24%), Positives = 179/596 (30%), Gaps = 118/596 (19%)
Query: 3193 SSAVAHLLNSITEPAPKHHRG-------KRSAGKAAGSPGDPWGQEGEAKKDSPGERAKP 3245
SSA H S TEP+P R +R A ++ S P + P R P
Sbjct: 201 SSASEH---STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA---RSGPSARGTP 254
Query: 3246 RARSTPSNPDG----AATPDSASATALADAGSPGP----PRTTPSPSPDPWAGGEPLLQA 3297
RA + PS P A P + A + GP P TPSPS P P LQ
Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314
Query: 3298 TPVHEACKDPSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLG 3357
P A PS+ G P H + SP L P+ P
Sbjct: 315 LPSPPATP-PSQATTSLGS----PTLQATHSFLPSPPLSPLATPPPQAPPA--------- 360
Query: 3358 GAHGLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGR 3417
L P LQ P A + Q + HL +
Sbjct: 361 -----LALPPLQAPP---------------SPPASPPLSPLATPSPQAPNALAVHLL--Q 398
Query: 3418 QPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAP----GPGEDRPPPRGSSPILS 3473
PF+ P +P +A P P AP P PP +SP +S
Sbjct: 399 APFS-----PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453
Query: 3474 EGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA 3533
+ P AP P L +P P P P PP S FP
Sbjct: 454 PSATPP------PQAPPPLAAPPLQLAKP--PPQAPPALATPPLQALPSPPAS---FPGQ 502
Query: 3534 LADGRGDCALDGALERPENEASPGSPGPLLQ-----QALPLGASLPRPGARGQDAE--GK 3586
L P +A P PLLQ A P + RP G D G
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562
Query: 3587 RAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA 3646
R L + P +R S S +S GP H SAT
Sbjct: 563 RLTLALAPGPPPPPSR--------------------SPSSTLS--GPDLAGHSSSATSTP 600
Query: 3647 ----GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGP 3702
G S + +AAS P A HP AP RG P P PG
Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG- 659
Query: 3703 SSQG------SGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL 3752
S+ G + P T G P P+ G A A SRSP RL
Sbjct: 660 SADGLCTIYETEGPESATPAPGALDPGPSPG-TSGGKAAAGAGAGASSRSPKQARL 714
Score = 51.6 bits (122), Expect = 2e-05
Identities = 186/763 (24%), Positives = 248/763 (32%), Gaps = 125/763 (16%)
Query: 2014 SRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD 2073
+RA L +P PP P + L AA G+ GR P + G+ AT
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAA----GAVGRKPLAERAGGIGG---ATIP 71
Query: 2074 SPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133
AP G P P S P++SP RA G + R P
Sbjct: 72 ESAPRAGPTRTSRP-PASGRGERAPPAKNTSPGPVSSPGRASG----------TTRPGPL 120
Query: 2134 PQQLLACSP----AWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQG 2189
Q+ L S A EA A + GA P T SP + + A G
Sbjct: 121 GQKGLRISAEETVARGKATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEVG 179
Query: 2190 EGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAV 2249
P PP + P+ S E S E SP A P AG
Sbjct: 180 LPRPAPSARPRPPT-----------EGPRKSVSSASEHSTTEP---SPA-ARRRPSAGGG 224
Query: 2250 SPSVAVRATGLSSTPTGDEAQAG---RGLPG-------PDPQSRGA--PPHTNPDRMPRG 2297
A R+ S+TP A++G RG P P P+ A PP P R
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284
Query: 2298 HSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGT--- 2354
+ P +++ L A + P+ PP+LQ P PA + TS P T
Sbjct: 285 -PALGPLSSSPLATPSPSAPPS-PSAPPSLQTL-PSPPATPPSQATTSLGSPTLQATHSF 341
Query: 2355 -PETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGP 2413
P S P P+ L L AP S P S + TP P P
Sbjct: 342 LPSPPLSPLATPPPQAPPA--LALPPLQAPPSP--------PASPPLSPLATPS--PQAP 389
Query: 2414 QDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGA 2473
L P + Q P P ++ P L+ A + P
Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA---APPLQVPPSP 446
Query: 2474 PAEP--SPAALPAQQPLEPLA----QKCQPPRKKSHRVS---------------GKERPN 2512
PA P SP+A P Q PLA Q +PP + ++ G+ +
Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 506
Query: 2513 HSRGDPSHVTQPPPAQG----SKEVLRAPGSPHSQQL-----HPPSPTEHEVDVKTPASK 2563
S P PP Q + +L+ P SP + PP+P T S
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-----GPDTSVSG 561
Query: 2564 PRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPV 2623
PR A P R P D HS ++ +LRG E
Sbjct: 562 PRLTLALAP--GPPPPPSRSPSSTLSGP--DLAGHSSSATSTPE-ELRGYDSGPEGGAAA 616
Query: 2624 SADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQ 2683
S ++ P A+++ P+ L+ G P A PP GPG +G +
Sbjct: 617 SPPPDAELAACHP----AAWSRGPAPPLAFRGAPGAPLPWPP---ATGPGSADGLCTIYE 669
Query: 2684 EALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQ-KGASAR 2725
G A PG L PG G + G+ G GAS+R
Sbjct: 670 ---TEGPESATPAPG--ALDPGPSPGTSGGKAAAGAGAGASSR 707
Score = 48.5 bits (114), Expect = 1e-04
Identities = 123/503 (24%), Positives = 162/503 (32%), Gaps = 84/503 (16%)
Query: 3424 GVRRPGAPGQKARAL--EGTLPSKRRRVAMPGSAPGPGEDR----PPPRGSSPILSEGSL 3477
G RPG GQK + E T+ + A SA G R P P SP ++ S
Sbjct: 113 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 172
Query: 3478 PALLHLCSEVAPSTTKGWPETLE--RPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALA 3535
A T G P RP P P + S H + P PAA
Sbjct: 173 AA----------GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TTEPSPAA-- 215
Query: 3536 DGRGDCALDGALERPENEASPGSPGPLLQQAL--PLGASLPRPGARGQDAEGK-----RA 3588
R + G L+RP + + S PL A P PR A + K R
Sbjct: 216 --RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 273
Query: 3589 PLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRG--TFHKGSATKPA 3646
P V ++ A A G + S S S P T AT P+
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATP---------SPSAPPSPSAPPSLQTLPSPPATPPS 324
Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARG------TENGMKPATPKAKP 3700
+S + +T S P+ P AP LA + P +P A P
Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384
Query: 3701 GPSS---------QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPER 3751
P + Q SP P P PAS + S +AT P++ PS + P +
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPV-SPSATPPSQAP-PSLAAPPLQ 441
Query: 3752 LPARAQAKSCTKGPREAGEQGPHGSLGP---------KEKGESSTKRKKGQVPGPARSES 3802
+P A Q P P + +T + PA
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501
Query: 3803 VGSFGRAPSAPDKPPRTPRKQATPS------RVLPTKPKPNSQNKPRPPPSEQRKAEPGH 3856
F + S P P TP QA P +V P+ P + PR PP+ P
Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT----PGPDT 557
Query: 3857 TQRKDRLGKAFPQGRPLLRPPKR 3879
+ RL A G P PP R
Sbjct: 558 SVSGPRLTLALAPGPP--PPPSR 578
Score = 46.2 bits (108), Expect = 6e-04
Identities = 185/808 (22%), Positives = 244/808 (30%), Gaps = 143/808 (17%)
Query: 1288 SKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQ- 1346
++ P AR PG L P P + P P V + + G A R PL G
Sbjct: 14 ARTPAARAPG-LLTP--RPPGSPRPPPPVTPAALRVLGAAGA-VGRKPLAERAGGIGGAT 69
Query: 1347 -PYSSPHSELFLGPKDLAGCFLEELHPKPSARD--APPASSSC---LCQDGEDAGSLEPQ 1400
P S+P + GP + P S R APPA ++ + G +G+ P
Sbjct: 70 IPESAPRA----GPTRTS-------RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 118
Query: 1401 LPRSPPG---TAETEPGRAASPPTLESSSLFPDLPVDRFDPP--------LYGSLSANRD 1449
P G +AE R + + S+L D P S +A +
Sbjct: 119 -PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177
Query: 1450 SGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPG 1509
GLP + PS P P P K +S T
Sbjct: 178 VGLP--------RPAPSARPRP----------------PTEGPRKSVSSASEHSTTEPSP 213
Query: 1510 AAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRV 1569
AA P G G LS T L S + RG PR A
Sbjct: 214 AARRRPSAGGGLQRPASRSLSSS-------ATPLSSPARSGPSARGTPRAPAHPSQPKPK 266
Query: 1570 ELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGT 1629
L PP + P S++ L S A ++ T+ + P T
Sbjct: 267 GL-QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS----PPAT 321
Query: 1630 WPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPP 1689
P A+ G L A + P SP P Q A QA PP
Sbjct: 322 PPSQATTSLGSPTLQ--ATHSFLPSPPLSPLAT----PPPQAPPALALPPLQA-----PP 370
Query: 1690 QDVCLP--EPSKQPGPQ---------LDAGSLAKCSPDQELSF------PKNKEAASSQE 1732
P P P PQ L A SP + F P + A +
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430
Query: 1733 SEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAP-DLAFQGDGAPPLDA 1791
+ SL P + +P A P + P P + P LA APP A
Sbjct: 431 APPSLAAPPLQ-----VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 485
Query: 1792 TWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVP 1851
T P A PS A G+A P+A P +P AP A L+ VP
Sbjct: 486 TPPLQALPSPPAS--FPGQAP--FSPSASLP------MSPLATPPPQAPPVLAAPLLQVP 535
Query: 1852 SPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSG 1911
S P L P R P PG S G L P PP +PS
Sbjct: 536 PSPPAS----------PTLQAPRRP---PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582
Query: 1912 LEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTAN 1971
GP +T + G+ G E G +
Sbjct: 583 ----------TLSGPDLAGHSSSATSTPEELRGYDSGPEG----GAAASPPPDAELAACH 628
Query: 1972 QLQPENGVSPGGTDNHASVNASPKTALTGP--TEGAVLLEKCKGSRAAMSLQEEAEPTPS 2029
G +P A P TGP +G + + +G +A +P PS
Sbjct: 629 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 688
Query: 2030 PPSPNRESLALALTAAHSRSGSEGRTPE 2057
P + ++ A A A SRS + R E
Sbjct: 689 PGTSGGKAAAGAGAGASSRSPKQARLGE 716
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 94.7 bits (234), Expect = 2e-18
Identities = 299/1256 (23%), Positives = 394/1256 (31%), Gaps = 248/1256 (19%)
Query: 1674 ASKTGLCQAEGDSRPPQDVC-LPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQE 1732
A+ +G +G P D+ + P PGPQ AG + K ++ A
Sbjct: 94 ATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD----KGEKGAPGPR 149
Query: 1733 SEDSLRLLPCEQRGGFLPEPGTADQPHR----GAPAPEAFGSP-AVHLAPDLAFQGDGAP 1787
D EPGT P G P P G A +A + GA
Sbjct: 150 GRDG--------------EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ 195
Query: 1788 PLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREA 1845
P G G + G GF+GN P G S PRG
Sbjct: 196 LGVMQGPMGPMGPRGPPGPAGA---------PGPQGFQGNPGEPGEPGVSGPMGPRGPPG 246
Query: 1846 WLVPVPSPACVSNTHPSRRSQDPALSPPIRQLQLPG----PGV-----------AKSKDG 1890
P P ++ + P PG PGV AK + G
Sbjct: 247 ---PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 303
Query: 1891 ILGL--QELTPAAQ-SPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQL 1947
G+ + +P SP + P GL G G A+G+ G P G
Sbjct: 304 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 363
Query: 1948 GLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVL 2007
G G G G+A T +G PE P G SP A G
Sbjct: 364 GPGFPGAPGAKGEAGPTGARG------PEGAQGPRG---EPGTPGSPGPAGASGNPGTDG 414
Query: 2008 LEKCKGSRAAMSLQ-EEAEPTP-SPPSPNRESLALALTAAHSRSGSEGRTPERA--SSPG 2063
+ KGS A + P P PP P + L G G E+ PG
Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 474
Query: 2064 LNKPLLATG----DSPAPSVGDLAACAP-SPTSAAHMPCSLGPLPREDPLTSPSRAQGGL 2118
P A G + + G+ P P P + G P +D L P A G
Sbjct: 475 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG-FPGQDGLAGPKGAPGER 533
Query: 2119 GGQLPASP-SCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCD 2177
G A P PG P L A G+ V P
Sbjct: 534 GPSGLAGPKGANGDPG-------RPGEPGLPGARGLTGRPGDAGPQGKVGP--------- 577
Query: 2178 PKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESP 2237
G+P ED PPG A P P+ + E P
Sbjct: 578 ------------SGAPGEDGRPGPPGPQGA------RGQPGVMGFPGPKGANGE-----P 614
Query: 2238 GRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGP-----DPQSRGAPPHTNPD 2292
G+A L G A GL P D G PGP + +GAP +
Sbjct: 615 GKAGEKGLPG---------APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 665
Query: 2293 RMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPED- 2351
+P P G + G VP E GP GE G+ +
Sbjct: 666 GLP------GPPGPPGEGGKPGD--QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 717
Query: 2352 ----PGTPET----GRSGATKMPRVTCPSTGL-------GLGRTTAPSSTASDFQSDSPQ 2396
PGTP T G SG P P GL G P D P+
Sbjct: 718 PRGLPGTPGTDGPKGASGPAGPPGAQGP-PGLQGMPGERGAAGIAGPKGDRGDVGEKGPE 776
Query: 2397 SHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSG 2456
P+GP PA NG+ P GP +A R
Sbjct: 777 GAPGKDGGRGLTGPIGPPG-----------PAGA-NGEKGEVGPPGPAG----SAGARGA 820
Query: 2457 PGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRG 2516
PG R PG P Q + ++ + +K G + P+ + G
Sbjct: 821 PG-----ERGETGPPGPAGFAGPPGADGQPGAK--GEQGEAGQKGDAGAPGPQGPSGAPG 873
Query: 2517 --DPSHVTQPPPAQGSKEVLRAPGSPHSQ-QLHPPSPTEH--EVDVKTPASKPRPDQARE 2571
P+ VT P A+G++ A G P + ++ PP + P+ K P AR
Sbjct: 874 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG 933
Query: 2572 DELHPKQAEK--REGRRW----RREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSA 2625
D P +A + +G + EP D PS +EG + L G+R I+ +
Sbjct: 934 DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ--GLAGQR----GIVGLPG 987
Query: 2626 DVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEA 2685
RG R P + + P +G P A G++ P PG+ A E +E
Sbjct: 988 Q-----RGERGFPGLPGPSGEPGK----QGAPGASGDRGPPGPVGPPGLTGPAGEPGRE- 1037
Query: 2686 LCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGA-SARGFWGP-------RETKALG 2737
G GA PPG DGAA + G+ GA A G GP T G
Sbjct: 1038 ---GSPGADGPPG--------RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086
Query: 2738 VCKESGSE-PAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTS-----SCLQ 2791
E+G++ P S A +R +G P GP G + P + + LQ
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQG-------PQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1139
Query: 2792 GLPDNPDTQG--GVQGPEGPT-----PDASGSSAKDPPSLFDDEVSFSQLFPPGGR 2840
GLP P G G GP GP+ P G S KD + + PPG R
Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG-----PPGPR 1190
Score = 92.8 bits (229), Expect = 6e-18
Identities = 306/1227 (24%), Positives = 381/1227 (31%), Gaps = 267/1227 (21%)
Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP--PAAENSFPGANFGVPPAEPEPIPKGSRPG 265
PGP +G +PG + P PA E P + G + P P+G R G
Sbjct: 100 PGPKGQKG----EPGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGDKGEKGAPGPRG-RDG 153
Query: 266 --GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGT--- 320
G+P P G P P + G+ FA Q G + E+A G
Sbjct: 154 EPGTPGN-------PGPPGPPGPPGPPGLGGN--------FAA-QMAGGFDEKAGGAQLG 197
Query: 321 ---GPAYPL----PTQPAPSPLPC-YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372
GP P+ P PA +P P +QG PG +SG + G +P D
Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG-VSGPMGPRGPPGPPGKPGDDGE 256
Query: 373 HKSLTKILPERPPSAQDGLG--STRGPPSSLPQRHFPGQ-----AYRASGVDTSPGPPDT 425
K PP Q G T G P R +PG A GV G P
Sbjct: 257 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG- 315
Query: 426 ELAAPGPP-PARLPQLWDPTAA------------PYPTPPGGPLAATRSMFFNGQPSPGQ 472
E +PGP P LP T P P P GP+ F G P +
Sbjct: 316 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG-AK 374
Query: 473 RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--------GSQGALGTA 524
P A P P P G P PAG G GS GA G A
Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGS------PGPAGASGNPGTDGIPGAKGSAGAPGIA 428
Query: 525 GKT--PGPREKL-------PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPH-- 573
G PGPR P Q G P + + G P +P G A PQ +P
Sbjct: 429 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP---GPAGPQGAPGPA 485
Query: 574 -------------GTPSLPPPRVVGAS-----PSESPLPSPA--------TNTAGSTCSS 607
G + PP GA P + L P + AG ++
Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 545
Query: 608 LSP-MSSSPANPSSEE-SQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEP 665
P P P + + PG GP P P E G P PP QP
Sbjct: 546 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP----GPPGPQGARGQPG- 600
Query: 666 AKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFP-------RAPPPYPTHHFS 718
FP P GA G E P G GL+G P A PP P
Sbjct: 601 VMGFPGPK---GANGEPGKAGEKGLP------GAPGLRGLPGKDGETGAAGPPGP----- 646
Query: 719 LSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPA 778
A R G A G Q PGPPG P
Sbjct: 647 -------------------------AGPAGERGEQG---APGPSGFQGLPGPPGPPGEGG 678
Query: 779 APR---VPADAHA-GLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDM 834
P VP +A A GL+ G+ + G LP T P AS
Sbjct: 679 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 738
Query: 835 EDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPE 894
A+ L GM + I D G +GP G+T
Sbjct: 739 PPGAQGPP----GLQGMPGERGAAGIAGPK----GDRGDVGEKGPEGAPGKDGGRGLTGP 790
Query: 895 SKAPPPLPAATPDPQTPRPGDRGCP-ARGRP----KTRSLGLAPTEADAPSQGRQQRRGK 949
P P A + PG G ARG P +T G A + G+ +G+
Sbjct: 791 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850
Query: 950 QLKLFRK-DLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRP----RTQAPGS 1004
Q + +K D + G SG+ G +G+ + + PP P R PGS
Sbjct: 851 QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 910
Query: 1005 RADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREY 1064
+P P P + + + +R PP R G G + +K
Sbjct: 911 NGNPGPPGPPGPSGKDGPKGARGDSGPP--------GRAGEPGLQGPAGPPGEKG----- 957
Query: 1065 DFASESEEDEQPPPRGPGFRGRRG-------RGEKRKEVELTQGPREDEPQKPRKAARQE 1117
+ + + PP G G+RG RGE+ GP + P K
Sbjct: 958 EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERG--FPGLPGPSGE----PGKQGAPG 1011
Query: 1118 AGGDGAPANPEEPGG-----SRPGPGRSPQARGP----------SRSLETGAAAREGGP- 1161
A GD P P P G PG SP A GP ETGA G P
Sbjct: 1012 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1071
Query: 1162 ------------KCADRPSVAPKDPL--QVPTNTETSEETRPSLDFPQEAKEPETAEESA 1207
K DR + P+ P + + EA EP E
Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP--GERGL 1129
Query: 1208 PDSTEFT--EALRSPPAACAGEMGAS--PGLLIPEQPP----PSRHD--------TGTPK 1251
FT + L PP +G+ GAS G P PP PS D G P
Sbjct: 1130 KGHRGFTGLQGLPGPPGP-SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188
Query: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPG 1278
P G T P G PG G PG
Sbjct: 1189 PRGRSGETGPAGPPGNPGPPGPPGPPG 1215
Score = 90.1 bits (222), Expect = 4e-17
Identities = 211/804 (26%), Positives = 258/804 (32%), Gaps = 117/804 (14%)
Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGG-QAQAME- 59
PG R R P T P PG P P L N A +AGG Q M+
Sbjct: 146 PGPRGRDGEPGTPGNPGPP----GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 201
Query: 60 ---------------LPEAQPRQARDGELKPPSLRG-QAPSSTPGKRGSPQTP-----PG 98
P Q Q GE P + G P PG G P PG
Sbjct: 202 PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG 261
Query: 99 RSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGT 158
++ + P G A G P + G+ R P LD + E +P G+
Sbjct: 262 KAGERGPPGPQG-ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK-GESGSPGENGS 319
Query: 159 GAPLRP-GLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPR-PPAPG------P 210
P+ P GLP + R P P+ P P APG P
Sbjct: 320 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379
Query: 211 PQSRGTSPLQ-----PGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPI-P 259
+RG Q PG+ +GA P P A+ S P P P P
Sbjct: 380 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439
Query: 260 KGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG 319
G + P G Q P + G + P G A G A + + E G
Sbjct: 440 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 499
Query: 320 TGPAYPLPTQPAPSPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHK 374
GP P + AP + GQ G G SG GA RP L
Sbjct: 500 VGPIGPPGERGAPGNRG-FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558
Query: 375 SLTKILPERP----------PSAQDGLGSTRGPPSSLPQRHFPGQAY--RASGVDTSPGP 422
+ + L RP PS G GPP R PG G + PG
Sbjct: 559 A--RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 616
Query: 423 PDTELAAPGPPPAR-LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAP 481
E PG P R LP T A P P GP G PS Q L P P
Sbjct: 617 AG-EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG-PSGFQGLPGPPGPP 674
Query: 482 ----LPWPQVLPTARPSPHGMEMLSRLPFPA--GGPEWQG--GSQGALGTAGKTPGPREK 533
P Q +P +P + FP G P QG G +G GT G T GP+
Sbjct: 675 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG-TDGPKGA 733
Query: 534 L-PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQP--------QVSPHGTPSLPPPRVV 584
PA G P L GM PG + G+A P + P G P R +
Sbjct: 734 SGPAGPPGAQGPPGL---QGM--PGERGAA-GIAGPKGDRGDVGEKGPEGAPGKDGGRGL 787
Query: 585 GASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQET 644
P P P+ A G P S+ A + E GP GP+ F PP +
Sbjct: 788 -TGPIGPPGPAGANGEKGEV-GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP 845
Query: 645 GSP-------------FPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691
G+ P P+ P P P+ P GA+G T FP
Sbjct: 846 GAKGEQGEAGQKGDAGAPGPQGPSGAPG---PQGPTGVTGPKGARGAQGPPGA---TGFP 899
Query: 692 HEGPEVGRGGLQGFPRAP-PPYPT 714
VG G G P P PP P+
Sbjct: 900 GAAGRVGPPGSNGNPGPPGPPGPS 923
Score = 83.6 bits (205), Expect = 4e-15
Identities = 216/837 (25%), Positives = 264/837 (31%), Gaps = 149/837 (17%)
Query: 6 PRGAPPPT-MTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQ 64
PRG P P TG L P+ PG + +G + G A P
Sbjct: 436 PRGPPGPQGATGPLGPKGQTGEPG----------IAGFKGEQGPKGEPGPAGPQGAPGPA 485
Query: 65 PRQARDGELKPPSLRGQAPSSTPGKRGSPQTP--PGRSPLQAPSRLAGRAEGSPPQRYIL 122
+ + G P G P PG+RG+P PG+ L P +G+P +R
Sbjct: 486 GEEGKRGARGEPG--GVGPIGPPGERGAPGNRGFPGQDGLAGP-------KGAPGERGPS 536
Query: 123 GIASSRTKPTLDETPENPQLEAAQ----LPEVDTPQGP--GTGAPLRPGLPRTEAQPAAE 176
G+A + P P L A+ P PQG +GAP G P A
Sbjct: 537 GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 596
Query: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236
F P + P PG P RG PG E A+G
Sbjct: 597 GQPGVMGFPGPKGA-----NGEPGKAGEKGLPGAPGLRGL----PGKDGETGAAGPPGPA 647
Query: 237 -PAAENSFPGA----NFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGA-STKPFPA 290
PA E GA F P P P +G +PG +GV + P L G + FP
Sbjct: 648 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD--QGVPGEAGAPGLVGPRGERGFPG 705
Query: 291 DVA--GHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLN 346
+ G GP P P+ A +GPA P P P QG PG G
Sbjct: 706 ERGSPGAQGLQGPRGLP-GTPGTDGPKGA--SGPAGP----PGAQGPPGLQGMPGERGAA 758
Query: 347 RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-----------PSAQDGLGSTR 395
+ G G P D I P P P G R
Sbjct: 759 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818
Query: 396 GPPSSLPQRHFPGQAYRAS--GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYP---- 449
G P + PG A A G D PG + A A P P+ AP P
Sbjct: 819 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878
Query: 450 --TPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP--TARPSPHGMEMLSRLP 505
T P G A G P R+ P S P P P + + P G S P
Sbjct: 879 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938
Query: 506 FPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTD-PGAQPLFFG 564
AG P G QG G G+ P + P+ G L G+ PG
Sbjct: 939 GRAGEP----GLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPG------- 987
Query: 565 VAQPQVSPHGTPSLPPPR-------VVGASPSESPLPSPA-----TNTAGSTCSSLSPMS 612
Q G P LP P GAS P P P T AG SP +
Sbjct: 988 ----QRGERGFPGLPGPSGEPGKQGAPGASGDRGP-PGPVGPPGLTGPAGEPGREGSPGA 1042
Query: 613 SSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAF--- 669
P + G G + P P GSP P+ PT Q + +A
Sbjct: 1043 DGPPGRDGAAG-VKGDRGETGAVGAPGAPGPPGSPGPAG------PTGKQGDRGEAGAQG 1095
Query: 670 ------PFPADGL-GAEGAFQCLEETPFPHE-GPEVGRG--GLQGFPRAPPPYPTHHFSL 719
P A G+ G +G E P E G + RG GLQG P P P
Sbjct: 1096 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGP-------- 1147
Query: 720 SSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSP 776
D+ S A R G + KDG PGP G P P
Sbjct: 1148 ---------------SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189
Score = 76.6 bits (187), Expect = 4e-13
Identities = 256/1081 (23%), Positives = 319/1081 (29%), Gaps = 221/1081 (20%)
Query: 425 TELAAPGPP-----PARLPQLWDPTAAPYPTPPGG---PLAATRSMFFNGQPSPGQRLCL 476
T PGP P + + P P P P G P G P P R
Sbjct: 95 TASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGE 154
Query: 477 PQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPA 536
P + P P P P P G+ G E GG+Q LG GP P
Sbjct: 155 PGTPGNPGPPG-PPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ--LGVMQGPMGPMG--PR 209
Query: 537 VRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSP 596
G+P + G +P GV+ P + P G P PP G E+ P
Sbjct: 210 GPPGPAGAPGPQGFQGNPGEPGEP---GVSGP-MGPRGPPG--PPGKPG-DDGEAGKPGK 262
Query: 597 ATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPSAFFHPPTHPQETGSP----FPSP 651
A +P P + + PG G P E+GSP P P
Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322
Query: 652 EPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGP-EVGRGGLQGFPRAPP 710
P LP + PA GA G + P P P VG G GFP AP
Sbjct: 323 MGPRGLPGE------RGRTGPAGAAGARGN----DGQPGPAGPPGPVGPAGGPGFPGAP- 371
Query: 711 PYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGP 770
+ G AR +G Q G
Sbjct: 372 -------------------------------------GAKGEAGPTGARGPEGAQGPRGE 394
Query: 771 PGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP-FPLPA 829
PG P P PA A +G+ +G + P +A P FP P
Sbjct: 395 PGTPGSPG----PAGA-------------SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437
Query: 830 SDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKA 889
+ T L G + Q+ P I + EP GP GP +
Sbjct: 438 GPPGPQG-------ATGPL-GPKGQTGEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEE 488
Query: 890 GVTPESKAPPPLPAATPDPQTPRPGDRGCPA-------RGRPKTRS-LGLAPTEADAPSQ 941
G P + P + PG+RG P +G P R GLA +
Sbjct: 489 GKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 548
Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERP-PPRPRRPRTQ 1000
GR G G G G + P G RP PP P+ R Q
Sbjct: 549 GRPGEPGLP----------GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598
Query: 1001 APGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNR 1060
PG P P+ E + + LP R + G G
Sbjct: 599 -PGVMGFPGPKGANG-----EPGKAGEKGLPGAPGLRGLPGKDGETGAA---------GP 643
Query: 1061 LREYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQ--------GPREDEPQ 1108
A E E P P G PG G G G K + + GPR +
Sbjct: 644 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703
Query: 1109 KPRKAARQEAGGDGAPANPEEPGGSRP----GPGRSPQARGP----SRSLETGAAAREGG 1160
+ + G G P PG P GP P A+GP E GAA G
Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI-AG 762
Query: 1161 PKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSP 1220
PK DR V K P P T P E E P A +P
Sbjct: 763 PK-GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 821
Query: 1221 ----------PAACAGEMGA--------------------SPGLLIPEQPPPSRHDTGTP 1250
PA AG GA +PG P P + TG
Sbjct: 822 GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVT 881
Query: 1251 KPSGSLANTAPHGSSPTPGVGSLLGGPG-----GTQAPVSHNSKDPPARQPGEFLAPVAN 1305
P G+ P G++ PG +G PG G P + KD P G+ P
Sbjct: 882 GPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-SGPPGR 940
Query: 1306 PSSTACPKPSVLSSKISSFGCD-PAGFNRDPLGVPVAKKGPQPYSSPHSELFL----GPK 1360
P+ + G D P+G P GPQ + + L G +
Sbjct: 941 AGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP--------GPQGLAGQRGIVGLPGQRGER 992
Query: 1361 DLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTA--ETEPGRAAS 1418
G L +P + AP AS G P P PPG EPGR S
Sbjct: 993 GFPG--LPGPSGEPGKQGAPGAS-----------GDRGPPGPVGPPGLTGPAGEPGREGS 1039
Query: 1419 P 1419
P
Sbjct: 1040 P 1040
Score = 73.9 bits (180), Expect = 3e-12
Identities = 261/1086 (24%), Positives = 342/1086 (31%), Gaps = 209/1086 (19%)
Query: 455 PLAATRSMFFNGQPSP-GQR--------LCLPQSAPLPWPQVLPTARPSPHGMEMLSRLP 505
P+ T +GQP P GQ+ + P+ P P P P G + +
Sbjct: 87 PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQG---PAGEQGPRG-DRGDKGE 142
Query: 506 FPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDP--GAQPLFF 563
A GP + G G G G PGP P GG+ A G + GAQ
Sbjct: 143 KGAPGPRGRDGEPGTPGNPGP-PGPPG--PPGPPGLGGNFAAQMAGGFDEKAGGAQ---L 196
Query: 564 GVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623
GV Q + P G P PP P+ +P P +P P E
Sbjct: 197 GVMQGPMGPMG-PRGPP------GPAGAPGPQG--------------FQGNPGEPG--EP 233
Query: 624 QLPGPLGPSAFFHPPTHPQ---ETGSPFPSPE--PPHSLPTHYQPEPAKAFPFPADGLGA 678
+ GP+GP PP P E G P + E PP P+ A+ FP G
Sbjct: 234 GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG-------PQGARGFPGTPGLPGV 286
Query: 679 EG--AFQCLEETPFPHEGPEV-GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQ 735
+G + L+ P V G G G +P P
Sbjct: 287 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR-------------------- 326
Query: 736 CDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAK 795
L G AR DG GPPG P P P A
Sbjct: 327 ------GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK------ 374
Query: 796 TFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQS 855
AG A G + P +P P AS + T+ + G + +
Sbjct: 375 --GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS----------GNPGTDGIPGAKGSA 422
Query: 856 DNPEIDSS--FIDVFADEEPSGPRGP-----SSGHP----LKSKAGVTPESKAPPPLPAA 904
P I + F P G GP +G P K + G P+ + P P
Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG--PKGEPGPAGPQG 480
Query: 905 TPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAA 964
P P G RG ARG P P E AP G + G+ G A
Sbjct: 481 APGP-AGEEGKRG--ARGEPGGVGPIGPPGERGAP--GNRGFPGQD-----------GLA 524
Query: 965 EGSGSGGGGRASGLR-PRRNDGLGERPPPRPRRPRTQ-APGSRADPAPRVPRAAALPEET 1022
G+ G SGL P+ +G P RP P A G P P+ P
Sbjct: 525 GPKGAPGERGPSGLAGPKGANG----DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGA 580
Query: 1023 RSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPG 1082
R PP GA G+ ++ K E + E+ P PG
Sbjct: 581 PGEDGRPGPPGPQ--------GARGQPGVMGFPGPKGANGE-----PGKAGEKGLPGAPG 627
Query: 1083 FRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPG-GSRPG----P 1137
RG G+ + GP ++ + A +G G P P PG G +PG P
Sbjct: 628 LRGLPGK-DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 686
Query: 1138 GR--SPQARGPSRSL----ETGAAAREG--------------GPKCADRPSVAPKDPLQV 1177
G +P GP E G+ +G GPK A P+ P Q
Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP--GAQG 744
Query: 1178 PTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIP 1237
P + R + + E P+ + R G +G PG P
Sbjct: 745 PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR----GLTGPIG-PPG---P 796
Query: 1238 EQPPPSRHDTGTPKPSGSL-ANTAP--HGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPAR 1294
+ + G P P+GS A AP G + PG G PG P + A
Sbjct: 797 AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAG 855
Query: 1295 QPGEFLAP-VANPSSTACPK-PSVLSSKISSFGCD-PAGFNRDP-----LGVPVAKKGPQ 1346
Q G+ AP PS P+ P+ ++ + G P G P +G P + P
Sbjct: 856 QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 915
Query: 1347 PYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGE--DAGSLEPQLPRS 1404
P P GPK G P R P GE + G P
Sbjct: 916 PPGPPGPSGKDGPKGARG------DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969
Query: 1405 PPGTAETEPGRA-ASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKT 1463
PPG R P FP LP +P G+ A+ D G P PP T
Sbjct: 970 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPP-GPVGPPGLT 1028
Query: 1464 VPSDPP 1469
P+ P
Sbjct: 1029 GPAGEP 1034
Score = 72.0 bits (175), Expect = 1e-11
Identities = 265/1132 (23%), Positives = 348/1132 (30%), Gaps = 234/1132 (20%)
Query: 6 PRGAPPPTMTGDLQPRQVASSPGHPSQP----PLEDNTPATRTTKGAR--EAGGQAQAME 59
PRG P P G P+ +PG P +P P+ P K EAG +A E
Sbjct: 208 PRGPPGPA--GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 265
Query: 60 LPEAQPRQARD-----------------------GELKPPSLRGQAPSSTPGKRGSP--- 93
P+ AR GE P ++G+ S +PG+ GSP
Sbjct: 266 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE--SGSPGENGSPGPM 323
Query: 94 --QTPPGRSPLQAPSRLAGRAEGSPPQRYILGI-----------------ASSRTKPTLD 134
+ PG P+ AG A G+ Q G A PT
Sbjct: 324 GPRGLPGERGRTGPAGAAG-ARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 382
Query: 135 ETPENPQLEAAQLPEVDTPQGPG----TGAPLRPGLPRTEAQPAAEELGFHRCF---QEP 187
PE Q E TP PG +G P G+P + A + F + P
Sbjct: 383 RGPEGAQ---GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439
Query: 188 PSSFTSTNYTSPSATPRPPA-------------PGPPQSRGTSPLQPGSYPEYQASGADS 234
P +T P P PGP +G PG E GA
Sbjct: 440 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA----PGPAGEEGKRGARG 495
Query: 235 WP-------PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287
P P E PG N G P + PKG+ P G++ +G +P
Sbjct: 496 EPGGVGPIGPPGERGAPG-NRGFPGQDGLAGPKGAPGERGPSGLAGP---KGANGDPGRP 551
Query: 288 FPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG---- 343
+ G G +P A P+ VG A +P P +GQPG
Sbjct: 552 GEPGLPGARGLTG-------RPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604
Query: 344 ----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-----------PSAQ 388
G N +G PGA P D + P P PS
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664
Query: 389 DGLGSTRGPPSSLPQ---RHFPGQAYRASGVDTSPGPPDT-----ELAAPGPP----PAR 436
GL GPP + + PG+A G GP E +PG P
Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPGEA----GAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720
Query: 437 LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQR----LCLPQSAPLPWPQVLPTAR 492
LP + P GP A G P G+R + P+ + P
Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP--GERGAAGIAGPKGDRGDVGEKGPEGA 778
Query: 493 PSPHGMEMLSRL---PFPAG--GPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547
P G L+ P PAG G + + G G G+AG P E+ + G P
Sbjct: 779 PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER------GETGPPGP 832
Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPS-ESPL----PSPATNTAG 602
+ G QP G Q + G P P+ +P + P P A G
Sbjct: 833 AGFAGPPGADGQPGAKG-EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 891
Query: 603 STCSSLSPMSSSPANP--SSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEP---PHSL 657
++ P ++ P S+ PGP GPS P ++G P + EP +
Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 951
Query: 658 PTHYQPEPAKAFPFPADG----------LGAEGAFQCLEETPFPHEGPEVGRGGLQGFPR 707
P + EP P A+G G G E FP G G QG P
Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 1011
Query: 708 AP----PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDG 763
A PP P L+ + + R S A R G + G
Sbjct: 1012 ASGDRGPPGPVGPPGLTGPA----------GEPGREGSPGADGPPGRD--GAAGVKGDRG 1059
Query: 764 HQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAAT 823
+ G PG P PP +P PA GD G P+ PS A
Sbjct: 1060 ETGAVGAPGAPGPPGSPG-PAGPTG----------KQGDRGEAGAQGPMG----PSGPAG 1104
Query: 824 PFPLPASDLDMEDDAKLDSLITEALNGME-----YQSDNPEIDSSFIDVFADEEPSGPRG 878
+ D + L G P S PSGPRG
Sbjct: 1105 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1164
Query: 879 PSSGHPLKSKAGVT----------PESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRS 928
P K G P ++ PA P P PG G P G +
Sbjct: 1165 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP-PGPPGPPGPGIDMSAF 1223
Query: 929 LGLAPTE----------ADAPSQGRQQRRGK---QLKLFRKDLDSGGAAEGS 967
GL P E AD + G +Q + LK ++S + EGS
Sbjct: 1224 AGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGS 1275
Score = 63.9 bits (154), Expect = 3e-09
Identities = 123/507 (24%), Positives = 162/507 (31%), Gaps = 66/507 (13%)
Query: 3414 RGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473
+G P F+G+ PG PG EG P + +PG A PG PRG
Sbjct: 656 QGAPGPSGFQGL--PGPPGPPG---EGGKPGDQ---GVPGEAGAPG--LVGPRGERGFPG 705
Query: 3474 EGSLPALLHLCSEVAPSTTKGW--PETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFP 3531
E P L T G P+ P P G + P Q P +
Sbjct: 706 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP-----GAQGPPGLQGMPGERGAAGI 760
Query: 3532 AALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAE-GKRAP 3589
A RGD G P + G GP+ P P GA G+ E G P
Sbjct: 761 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI---------GPPGPAGANGEKGEVGPPGP 811
Query: 3590 LVFSGKRRAPGARGRCA----------PDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHK 3639
+G R APG RG P + ++ E GP+G
Sbjct: 812 AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 871
Query: 3640 GSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAK 3699
P G + K A P A FP A G + P + G P P K
Sbjct: 872 PGPQGPTGV-TGPKGARGAQGPPGATGFP----GAAGRVGPPG-SNGNPGPPGPPGPSGK 925
Query: 3700 PGPSSQGSGSPRPGTKTGGGSQ-PQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQA 3758
GP S PG G Q P G+ P+ P P P+ L A
Sbjct: 926 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP---PGPQGL---AGQ 979
Query: 3759 KSCTKGPREAGEQGPHGSLGPKEK-------GESSTKRKKGQVPGPARSESVGSFGR--A 3809
+ P + GE+G G GP + G S + G V P + G GR +
Sbjct: 980 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 1039
Query: 3810 PSAPDKPPRTPRKQATPSR----VLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGK 3865
P A P R R + P P P ++ + G + +G
Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099
Query: 3866 AFPQGRPLLRPPK--RGTAVHGAEPAE 3890
+ P G ++ P+ RG EP E
Sbjct: 1100 SGPAGARGIQGPQGPRGDKGEAGEPGE 1126
Score = 61.2 bits (147), Expect = 2e-08
Identities = 170/653 (26%), Positives = 209/653 (32%), Gaps = 138/653 (21%)
Query: 2 PGER--PRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-----NTPATRTTKGAREAGGQ 54
PG++ P A P + G R G P L+ TP T KGA G
Sbjct: 680 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739
Query: 55 AQAMELPEAQPRQARDGELK---PPSLRG----QAPSSTPGKRGS-----PQTPPGRSPL 102
A P Q G P RG + P PGK G P PPG
Sbjct: 740 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG---- 795
Query: 103 QAPSRLAG-RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAP 161
P+ G + E PP G A +R P + E P G P
Sbjct: 796 --PAGANGEKGEVGPPGP--AGSAGARGAP-------------GERGETGPPGPAGFAGP 838
Query: 162 LRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAP----GPPQSRGT 216
P + QP A+ E G Q+ + PS P P P GP +RG
Sbjct: 839 -----PGADGQPGAKGEQG--EAGQKGDAGAPGPQ--GPSGAPGPQGPTGVTGPKGARGA 889
Query: 217 SPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPI----PKGSRPGGSPRGVS 272
PG+ A+G P N PG PP P P PKG+R P G +
Sbjct: 890 QG-PPGATGFPGAAGRVG--PPGSNGNPG-----PPGPPGPSGKDGPKGARGDSGPPGRA 941
Query: 273 FQFPFPALHGASTKPF----PADVAGHAFTNGPLVFAFHQPQGAWPEEAV----GTGPAY 324
+ P L G + P P D G + GP PQG + + G
Sbjct: 942 GE---PGLQGPAGPPGEKGEPGD-DGPSGAEGP-----PGPQGLAGQRGIVGLPGQRGER 992
Query: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384
P P PS P QG PG G + PG A P + + + P
Sbjct: 993 GFPGLPGPSGEPGKQGAPGASGDRGP-PGPVGPPGLTGPAGEPGREGSPGA------DGP 1045
Query: 385 PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP-PARLPQLWDP 443
P +DG +G PG +PGPP +PGP P
Sbjct: 1046 PG-RDGAAGVKGDRGETGAVGAPG----------APGPP----GSPGPAGPTGKQGDRGE 1090
Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503
A P P GP A G P A P + L R G L
Sbjct: 1091 AGAQGPMGPSGPAGA------RGIQGPQGPRGDKGEAGEPGERGLKGHR----GFTGLQG 1140
Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPR-EKLPAVRSSQGGSPALFTYNGMTDPGAQPLF 562
LP GP G QGA G AG + GPR P S + G+ NG+ P P
Sbjct: 1141 LP----GPPGPSGDQGASGPAGPS-GPRGPPGPVGPSGKDGA------NGIPGPIGPPGP 1189
Query: 563 FGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSP 615
G + P G P P P P P P + S + L P P
Sbjct: 1190 RG-RSGETGPAGPPGNPGP------PGPPGPPGPGIDM--SAFAGLGPREKGP 1233
Score = 55.1 bits (131), Expect = 1e-06
Identities = 117/479 (24%), Positives = 144/479 (30%), Gaps = 72/479 (15%)
Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488
G G + E P R R PG+ PG PP P L + E A
Sbjct: 132 GPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKA 191
Query: 3489 PSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECP-----PPSLSPF-PAALADGRGDC 3541
G + P+ P P G P Q P P P P G
Sbjct: 192 GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP 251
Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR-PGARG----QDAEGKRAPLVFSGKR 3596
DG +P G PGP + P LP G RG A+G+ G+
Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311
Query: 3597 RAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGC-------- 3648
+PG G P GPRG + T PAG
Sbjct: 312 GSPGENGSPGP-----------------------MGPRGLPGERGRTGPAGAAGARGNDG 348
Query: 3649 QSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSG 3708
Q P+ FP P A G P ARG E P PG
Sbjct: 349 QPGPAGPPGPVGPAGGPGFPGAP-GAKGEAGPTG-ARGPEGAQGPRGEPGTPGSPGPAGA 406
Query: 3709 SPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREA 3768
S PGT G++ + + A P P P P P+ K T P A
Sbjct: 407 SGNPGTDGIPGAKGSAGAPGI----AGAPGFPG-PRGPPGPQGATGPLGPKGQTGEPGIA 461
Query: 3769 ---GEQGPHGSLGPK----EKGESSTKRKKGQVPGPARSESVGSFGR--APSAPDKP--- 3816
GEQGP G GP G + + K+G P +G G AP P
Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 521
Query: 3817 ----PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGR 3871
P+ + PS + K +P P PG R G A PQG+
Sbjct: 522 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP------GLPGARGLTGRPGDAGPQGK 574
Score = 54.3 bits (129), Expect = 2e-06
Identities = 116/469 (24%), Positives = 154/469 (32%), Gaps = 56/469 (11%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG G LP +R R G+A G D P P V
Sbjct: 314 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPP--------------GPV 359
Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA- 3546
P+ G+P + RG E + P SP PA + G + GA
Sbjct: 360 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 419
Query: 3547 --LERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFS-GKRRAPGARG 3603
P +PG PGP P GA+ P G +GQ E A G + PG G
Sbjct: 420 GSAGAPGIAGAPGFPGPRGPPG-PQGATGPL-GPKGQTGEPGIAGFKGEQGPKGEPGPAG 477
Query: 3604 -RCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP-----AGCQSSSKDR-- 3655
+ AP E+ E + G RG G+ P AG + + +R
Sbjct: 478 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA--PGNRGFPGQDGLAGPKGAPGERGP 535
Query: 3656 SAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTK 3715
S + P A P P + PG ARG A P+ K GPS RPG
Sbjct: 536 SGLAGPKGANGDPGRPGEPG---LPG--ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP- 589
Query: 3716 TGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP---REAGEQG 3772
PQ A GQ P FP A P +A K P G+ G
Sbjct: 590 ----PGPQGARGQ--------PGVMGFPGPKGANGE-PGKAGEKGLPGAPGLRGLPGKDG 636
Query: 3773 PHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP--PRTPRKQATPSRVL 3830
G+ GP + +R + PGP+ + + P KP P + P V
Sbjct: 637 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 696
Query: 3831 PTKPK--PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPP 3877
P + P + P + + PG G + P G P + P
Sbjct: 697 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 745
Score = 46.2 bits (108), Expect = 6e-04
Identities = 107/391 (27%), Positives = 128/391 (32%), Gaps = 65/391 (16%)
Query: 3415 GGRQPFAFRGVRRP-GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473
G P GV P GA G + P RV PGS PG PP P
Sbjct: 870 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP----GPSGK 925
Query: 3474 EGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA 3533
+G A + P G P L+ P P + + E PP P
Sbjct: 926 DGPKGAR----GDSGPPGRAGEPG-LQGPAGPPGEKGEPGDDGPSGAEGPPG-----PQG 975
Query: 3534 LADGRGDCALDGALERPENEASPGSPGPLLQ---QALPLGASLPR--PGARGQDAEGKRA 3588
LA RG L G +R E PG PGP + Q P GAS R PG G G
Sbjct: 976 LAGQRGIVGLPG--QRGER-GFPGLPGPSGEPGKQGAP-GASGDRGPPGPVGPP--GLTG 1029
Query: 3589 PLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGC 3648
P G+ +PGA G P + E + GP G+ PAG
Sbjct: 1030 PAGEPGREGSPGADG--PPGRDGAAGVKGDRGETGAVGAPGAPGPPGS------PGPAGP 1081
Query: 3649 QSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPG-PSSQGS 3707
DR A P+ P G ARG + P K + G P +G
Sbjct: 1082 TGKQGDRGEAGAQG-----PMGPSGPAG-------ARGIQGPQGPRGDKGEAGEPGERGL 1129
Query: 3708 GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL--------------P 3753
R T G P SG + A+ PA PS P P P P
Sbjct: 1130 KGHRGFTGLQGLPGPPGPSGD---QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP 1186
Query: 3754 ARAQAKSCTKGPR-EAGEQGPHGSLGPKEKG 3783
+ +S GP G GP G GP G
Sbjct: 1187 PGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1217
Score = 45.1 bits (105), Expect = 0.001
Identities = 95/411 (23%), Positives = 125/411 (30%), Gaps = 59/411 (14%)
Query: 3504 DPVTHPIRGCELPS-NHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPL 3562
D + ++ C P EC P + P A A G+ P + G PG +
Sbjct: 66 DIICEDVKDCLSPEIPFGECCP--ICPTDLATASGQ-----------PGPKGQKGEPGDI 112
Query: 3563 LQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEV 3622
P G P+ A Q G R G++ APG RGR + E
Sbjct: 113 KDIVGPKGPPGPQGPAGEQGPRGDRGD---KGEKGAPGPRGR--------------DGEP 155
Query: 3623 SSSHMVSEGGPRG-TFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP- 3680
+ GP G G A + D A ++ P+ P G P
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215
Query: 3681 ---------GELARGTENGMK-PATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQ 3730
G E G+ P P+ PGP + G K G + P Q
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG-KPGKAGERGPPGPQGA 274
Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQA-----KSCTKGPREAGEQGPHGSLG-PKEKGE 3784
TP P P A+ +A K + P E G GP G G P E+G
Sbjct: 275 RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 334
Query: 3785 SSTKRKKGQ-----VPGPARSES-VGSFGRA--PSAPD-KPPRTPRKQATPSRVLPTKPK 3835
+ G PGPA VG G P AP K P P + +
Sbjct: 335 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 394
Query: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGA 3886
P + P P + G K G G P P+ GA
Sbjct: 395 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 445
Score = 40.0 bits (92), Expect = 0.046
Identities = 56/236 (23%), Positives = 68/236 (28%), Gaps = 30/236 (12%)
Query: 3679 APGELAR----GTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA 3734
APG R GT P P PGP G + GG + QL
Sbjct: 145 APGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF---AAQMAGGFDEKAGGAQLG--VM 199
Query: 3735 TTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK-------EKGESST 3787
P P P P P P + P E G GP G GP + GE+
Sbjct: 200 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 259
Query: 3788 KRKKGQVPGPARSESVGSFGRAPSAPDKPPRT-------PRKQATPSRVLPTKPKPNSQN 3840
K G+ GP + F P P + +A V P
Sbjct: 260 PGKAGE-RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 318
Query: 3841 KPRP------PPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAE 3890
P P P R G + G+ P G P P G GA A+
Sbjct: 319 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 374
Score = 38.9 bits (89), Expect = 0.10
Identities = 101/428 (23%), Positives = 128/428 (29%), Gaps = 68/428 (15%)
Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS-EGSL 3477
P F G PGA GQ E ++ PG P P P+G + + +G+
Sbjct: 832 PAGFAGP--PGADGQPGAKGEQGEAGQKGDAGAPG--PQGPSGAPGPQGPTGVTGPKGAR 887
Query: 3478 PALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADG 3537
A P G+P R P ++ G P P + +
Sbjct: 888 GAQ-------GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 940
Query: 3538 RGDCALDGALERPENEASPGSPGPLLQQALPLGASLPR-------PGARGQDA-EGKRAP 3589
G+ L G P + PG GP + P L PG RG+ G P
Sbjct: 941 AGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 1000
Query: 3590 LVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649
GK+ APGA G + GP G T PAG
Sbjct: 1001 SGEPGKQGAPGASG--------------------------DRGPPGPVGPPGLTGPAGEP 1034
Query: 3650 SSSKDRSAASTPSK----ALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQ 3705
A P + +K AVG APG A G PA P K G +
Sbjct: 1035 GREGSPGADGPPGRDGAAGVKGDRGETGAVG--APG--APGPPGSPGPAGPTGKQGDRGE 1090
Query: 3706 GS--GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTK 3763
G P G P + A P + R R Q
Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE-----RGLKGHRGFTGLQGLPGPP 1145
Query: 3764 GPR----EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA-PSAPDKPPR 3818
GP +G GP G GP S K +PGP G GR+ + P PP
Sbjct: 1146 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP--GPRGRSGETGPAGPPG 1203
Query: 3819 TPRKQATP 3826
P P
Sbjct: 1204 NPGPPGPP 1211
Score = 37.7 bits (86), Expect = 0.23
Identities = 36/111 (32%), Positives = 43/111 (38%), Gaps = 17/111 (15%)
Query: 3187 PGGLEGSSAVAHLLNSITE------PAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAK 3235
P GL G + L E P P GK+ A A+G G P G G A
Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA- 1031
Query: 3236 KDSPGERAKPRARSTPSNPDGAA--TPDSASATALADAGSPGPPRTTPSPS 3284
PG P A P DGAA D A+ G+PGPP +P P+
Sbjct: 1032 -GEPGREGSPGADGPPGR-DGAAGVKGDRGETGAVGAPGAPGPP-GSPGPA 1079
Score = 35.4 bits (80), Expect = 1.1
Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNP-DGAATPDSAS 3264
P K HRG A G G P G +GE+ SPGE P P + T + +
Sbjct: 284 PGVKGHRGYPGLDGAKGEAGAP-GVKGES--GSPGENGSPGPMGPRGLPGERGRTGPAGA 340
Query: 3265 ATALADAGSPGP--PRTTPSPSPDPWAGGEP 3293
A A + G PGP P P+ P G P
Sbjct: 341 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAP 371
Score = 34.3 bits (77), Expect = 2.5
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 22/94 (23%)
Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSP-------GERAKPRARSTPSNPDGA 3257
+P PK +G+ K P P G +G A + P GE+ P R P
Sbjct: 99 QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP--- 155
Query: 3258 ATPDSASATALADAGSPGPPRTTPSPSPDPWAGG 3291
TP G+PGPP P P P GG
Sbjct: 156 GTP-----------GNPGPPG-PPGPPGPPGLGG 177
Score = 32.7 bits (73), Expect = 7.3
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264
+P K +G+ AG+PG P G G +PG + P + P GA P A+
Sbjct: 844 QPGAKGEQGEAGQKGDAGAPG-PQGPSG-----APGPQG-PTGVTGPKGARGAQGPPGAT 896
Query: 3265 ATALADAGSPGPPRTTPSPSP 3285
A AG GPP + +P P
Sbjct: 897 GFPGA-AGRVGPPGSNGNPGP 916
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 94.7 bits (234), Expect = 2e-18
Identities = 300/1253 (23%), Positives = 395/1253 (31%), Gaps = 259/1253 (20%)
Query: 1693 CLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEP 1752
C + +QPGP+ G + +++ PK E P
Sbjct: 23 CQGQDVRQPGPK---GQKGEPGDIKDIVGPKGPPGPQGPAGEQG-------------PRG 66
Query: 1753 GTADQPHRGAPAPEAF-GSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQ------- 1804
D+ +GAP P G P P G PP P G + AAQ
Sbjct: 67 DRGDKGEKGAPGPRGRDGEPGTPGNP-----GPPGPP-GPPGPPGLGGNFAAQMAGGFDE 120
Query: 1805 ---GHSAGRAGGHLHPT--------AGRPG---FEGNEFAPA--GASSLTAPRGREAWLV 1848
G G G + P AG PG F+GN P G S PRG
Sbjct: 121 KAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG--- 177
Query: 1849 PVPSPACVSNTHPSRRSQDPALSPPIRQLQLPG----PGV-----------AKSKDGILG 1893
P P ++ + P PG PGV AK + G G
Sbjct: 178 PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG 237
Query: 1894 L--QELTPAAQ-SPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLE 1950
+ + +P SP + P GL G G A+G+ G P G G
Sbjct: 238 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 297
Query: 1951 ADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEK 2010
G G G+A T +G PE P G SP A G +
Sbjct: 298 FPGAPGAKGEAGPTGARG------PEGAQGPRG---EPGTPGSPGPAGASGNPGTDGIPG 348
Query: 2011 CKGSRAAMSLQ-EEAEPTP-SPPSPNRESLALALTAAHSRSGSEGRTPERA--SSPGLNK 2066
KGS A + P P PP P + L G G E+ PG
Sbjct: 349 AKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG 408
Query: 2067 PLLATG----DSPAPSVGDLAACAP-SPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQ 2121
P A G + + G+ P P P + G P +D L P A G G
Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRG-FPGQDGLAGPKGAPGERGPS 467
Query: 2122 LPASP-SCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKE 2180
A P PG P L A G+ V P
Sbjct: 468 GLAGPKGANGDPG-------RPGEPGLPGARGLTGRPGDAGPQGKVGP------------ 508
Query: 2181 ALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRA 2240
G+P ED PPG A P P+ + E PG+A
Sbjct: 509 ---------SGAPGEDGRPGPPGPQGA------RGQPGVMGFPGPKGANGE-----PGKA 548
Query: 2241 TSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGP-----DPQSRGAPPHTNPDRMP 2295
L G A GL P D G PGP + +GAP + +P
Sbjct: 549 GEKGLPG---------APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP 599
Query: 2296 RGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPED---- 2351
P G + G VP E GP GE G+ +
Sbjct: 600 ------GPPGPPGEGGKPGD--QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651
Query: 2352 -PGTPET----GRSGATKMPRVTCPSTGL-------GLGRTTAPSSTASDFQSDSPQSHR 2399
PGTP T G SG P P GL G P D P+
Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGP-PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP 710
Query: 2400 NASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGL 2459
P+GP PA NG+ P GP +A R PG
Sbjct: 711 GKDGGRGLTGPIGPPG-----------PAGA-NGEKGEVGPPGPAG----SAGARGAPG- 753
Query: 2460 SRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRG--D 2517
R PG P Q + ++ + +K G + P+ + G
Sbjct: 754 ----ERGETGPPGPAGFAGPPGADGQPGAK--GEQGEAGQKGDAGAPGPQGPSGAPGPQG 807
Query: 2518 PSHVTQPPPAQGSKEVLRAPGSPHSQ-QLHPPSPTEH--EVDVKTPASKPRPDQAREDEL 2574
P+ VT P A+G++ A G P + ++ PP + P+ K P AR D
Sbjct: 808 PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867
Query: 2575 HPKQAEK--REGRRW----RREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVI 2628
P +A + +G + EP D PS +EG + L G+R I+ +
Sbjct: 868 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ--GLAGQR----GIVGLPGQ-- 919
Query: 2629 SDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCA 2688
RG R P + + P +G P A G++ P PG+ A E +E
Sbjct: 920 ---RGERGFPGLPGPSGEPGK----QGAPGASGDRGPPGPVGPPGLTGPAGEPGRE---- 968
Query: 2689 GETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGA-SARGFWGP-------RETKALGVCK 2740
G GA PPG DGAA + G+ GA A G GP T G
Sbjct: 969 GSPGADGPPG--------RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG 1020
Query: 2741 ESGSE-PAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTS-----SCLQGLP 2794
E+G++ P S A +R +G P GP G + P + + LQGLP
Sbjct: 1021 EAGAQGPMGPSGPAGARGIQG-------PQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP 1073
Query: 2795 DNPDTQG--GVQGPEGPT-----PDASGSSAKDPPSLFDDEVSFSQLFPPGGR 2840
P G G GP GP+ P G S KD + + PPG R
Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG-----PPGPR 1121
Score = 92.8 bits (229), Expect = 6e-18
Identities = 306/1227 (24%), Positives = 381/1227 (31%), Gaps = 267/1227 (21%)
Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP--PAAENSFPGANFGVPPAEPEPIPKGSRPG 265
PGP +G +PG + P PA E P + G + P P+G R G
Sbjct: 31 PGPKGQKG----EPGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGDKGEKGAPGPRG-RDG 84
Query: 266 --GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGT--- 320
G+P P G P P + G+ FA Q G + E+A G
Sbjct: 85 EPGTPGN-------PGPPGPPGPPGPPGLGGN--------FAA-QMAGGFDEKAGGAQLG 128
Query: 321 ---GPAYPL----PTQPAPSPLPC-YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372
GP P+ P PA +P P +QG PG +SG + G +P D
Sbjct: 129 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG-VSGPMGPRGPPGPPGKPGDDGE 187
Query: 373 HKSLTKILPERPPSAQDGLG--STRGPPSSLPQRHFPGQ-----AYRASGVDTSPGPPDT 425
K PP Q G T G P R +PG A GV G P
Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG- 246
Query: 426 ELAAPGPP-PARLPQLWDPTAA------------PYPTPPGGPLAATRSMFFNGQPSPGQ 472
E +PGP P LP T P P P GP+ F G P +
Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG-AK 305
Query: 473 RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--------GSQGALGTA 524
P A P P P G P PAG G GS GA G A
Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGS------PGPAGASGNPGTDGIPGAKGSAGAPGIA 359
Query: 525 GKT--PGPREKL-------PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPH-- 573
G PGPR P Q G P + + G P +P G A PQ +P
Sbjct: 360 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP---GPAGPQGAPGPA 416
Query: 574 -------------GTPSLPPPRVVGAS-----PSESPLPSPA--------TNTAGSTCSS 607
G + PP GA P + L P + AG ++
Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 476
Query: 608 LSP-MSSSPANPSSEE-SQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEP 665
P P P + + PG GP P P E G P PP QP
Sbjct: 477 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP----GPPGPQGARGQPG- 531
Query: 666 AKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFP-------RAPPPYPTHHFS 718
FP P GA G E P G GL+G P A PP P
Sbjct: 532 VMGFPGPK---GANGEPGKAGEKGLP------GAPGLRGLPGKDGETGAAGPPGP----- 577
Query: 719 LSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPA 778
A R G A G Q PGPPG P
Sbjct: 578 -------------------------AGPAGERGEQG---APGPSGFQGLPGPPGPPGEGG 609
Query: 779 APR---VPADAHA-GLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDM 834
P VP +A A GL+ G+ + G LP T P AS
Sbjct: 610 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 669
Query: 835 EDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPE 894
A+ L GM + I D G +GP G+T
Sbjct: 670 PPGAQGPP----GLQGMPGERGAAGIAGPK----GDRGDVGEKGPEGAPGKDGGRGLTGP 721
Query: 895 SKAPPPLPAATPDPQTPRPGDRGCP-ARGRP----KTRSLGLAPTEADAPSQGRQQRRGK 949
P P A + PG G ARG P +T G A + G+ +G+
Sbjct: 722 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 781
Query: 950 QLKLFRK-DLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRP----RTQAPGS 1004
Q + +K D + G SG+ G +G+ + + PP P R PGS
Sbjct: 782 QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 841
Query: 1005 RADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREY 1064
+P P P + + + +R PP R G G + +K
Sbjct: 842 NGNPGPPGPPGPSGKDGPKGARGDSGPP--------GRAGEPGLQGPAGPPGEKG----- 888
Query: 1065 DFASESEEDEQPPPRGPGFRGRRG-------RGEKRKEVELTQGPREDEPQKPRKAARQE 1117
+ + + PP G G+RG RGE+ GP + P K
Sbjct: 889 EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERG--FPGLPGPSGE----PGKQGAPG 942
Query: 1118 AGGDGAPANPEEPGG-----SRPGPGRSPQARGP----------SRSLETGAAAREGGP- 1161
A GD P P P G PG SP A GP ETGA G P
Sbjct: 943 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1002
Query: 1162 ------------KCADRPSVAPKDPL--QVPTNTETSEETRPSLDFPQEAKEPETAEESA 1207
K DR + P+ P + + EA EP E
Sbjct: 1003 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP--GERGL 1060
Query: 1208 PDSTEFT--EALRSPPAACAGEMGAS--PGLLIPEQPP----PSRHD--------TGTPK 1251
FT + L PP +G+ GAS G P PP PS D G P
Sbjct: 1061 KGHRGFTGLQGLPGPPGP-SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119
Query: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPG 1278
P G T P G PG G PG
Sbjct: 1120 PRGRSGETGPAGPPGNPGPPGPPGPPG 1146
Score = 90.1 bits (222), Expect = 4e-17
Identities = 211/804 (26%), Positives = 258/804 (32%), Gaps = 117/804 (14%)
Query: 2 PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGG-QAQAME- 59
PG R R P T P PG P P L N A +AGG Q M+
Sbjct: 77 PGPRGRDGEPGTPGNPGPP----GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 132
Query: 60 ---------------LPEAQPRQARDGELKPPSLRG-QAPSSTPGKRGSPQTP-----PG 98
P Q Q GE P + G P PG G P PG
Sbjct: 133 PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG 192
Query: 99 RSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGT 158
++ + P G A G P + G+ R P LD + E +P G+
Sbjct: 193 KAGERGPPGPQG-ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK-GESGSPGENGS 250
Query: 159 GAPLRP-GLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPR-PPAPG------P 210
P+ P GLP + R P P+ P P APG P
Sbjct: 251 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310
Query: 211 PQSRGTSPLQ-----PGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPI-P 259
+RG Q PG+ +GA P P A+ S P P P P
Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370
Query: 260 KGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG 319
G + P G Q P + G + P G A G A + + E G
Sbjct: 371 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430
Query: 320 TGPAYPLPTQPAPSPLPCYQGQPG-----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHK 374
GP P + AP + GQ G G SG GA RP L
Sbjct: 431 VGPIGPPGERGAPGNRG-FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 489
Query: 375 SLTKILPERP----------PSAQDGLGSTRGPPSSLPQRHFPGQAY--RASGVDTSPGP 422
+ + L RP PS G GPP R PG G + PG
Sbjct: 490 A--RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 547
Query: 423 PDTELAAPGPPPAR-LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAP 481
E PG P R LP T A P P GP G PS Q L P P
Sbjct: 548 AG-EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG-PSGFQGLPGPPGPP 605
Query: 482 ----LPWPQVLPTARPSPHGMEMLSRLPFPA--GGPEWQG--GSQGALGTAGKTPGPREK 533
P Q +P +P + FP G P QG G +G GT G T GP+
Sbjct: 606 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG-TDGPKGA 664
Query: 534 L-PAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQP--------QVSPHGTPSLPPPRVV 584
PA G P L GM PG + G+A P + P G P R +
Sbjct: 665 SGPAGPPGAQGPPGL---QGM--PGERGAA-GIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718
Query: 585 GASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQET 644
P P P+ A G P S+ A + E GP GP+ F PP +
Sbjct: 719 -TGPIGPPGPAGANGEKGEV-GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP 776
Query: 645 GSP-------------FPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFP 691
G+ P P+ P P P+ P GA+G T FP
Sbjct: 777 GAKGEQGEAGQKGDAGAPGPQGPSGAPG---PQGPTGVTGPKGARGAQGPPGA---TGFP 830
Query: 692 HEGPEVGRGGLQGFPRAP-PPYPT 714
VG G G P P PP P+
Sbjct: 831 GAAGRVGPPGSNGNPGPPGPPGPS 854
Score = 83.6 bits (205), Expect = 4e-15
Identities = 216/837 (25%), Positives = 264/837 (31%), Gaps = 149/837 (17%)
Query: 6 PRGAPPPT-MTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQ 64
PRG P P TG L P+ PG + +G + G A P
Sbjct: 367 PRGPPGPQGATGPLGPKGQTGEPG----------IAGFKGEQGPKGEPGPAGPQGAPGPA 416
Query: 65 PRQARDGELKPPSLRGQAPSSTPGKRGSPQTP--PGRSPLQAPSRLAGRAEGSPPQRYIL 122
+ + G P G P PG+RG+P PG+ L P +G+P +R
Sbjct: 417 GEEGKRGARGEPG--GVGPIGPPGERGAPGNRGFPGQDGLAGP-------KGAPGERGPS 467
Query: 123 GIASSRTKPTLDETPENPQLEAAQ----LPEVDTPQGP--GTGAPLRPGLPRTEAQPAAE 176
G+A + P P L A+ P PQG +GAP G P A
Sbjct: 468 GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 527
Query: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236
F P + P PG P RG PG E A+G
Sbjct: 528 GQPGVMGFPGPKGA-----NGEPGKAGEKGLPGAPGLRGL----PGKDGETGAAGPPGPA 578
Query: 237 -PAAENSFPGA----NFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGA-STKPFPA 290
PA E GA F P P P +G +PG +GV + P L G + FP
Sbjct: 579 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD--QGVPGEAGAPGLVGPRGERGFPG 636
Query: 291 DVA--GHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG--GLN 346
+ G GP P P+ A +GPA P P P QG PG G
Sbjct: 637 ERGSPGAQGLQGPRGLP-GTPGTDGPKGA--SGPAGP----PGAQGPPGLQGMPGERGAA 689
Query: 347 RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-----------PSAQDGLGSTR 395
+ G G P D I P P P G R
Sbjct: 690 GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 749
Query: 396 GPPSSLPQRHFPGQAYRAS--GVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYP---- 449
G P + PG A A G D PG + A A P P+ AP P
Sbjct: 750 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809
Query: 450 --TPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP--TARPSPHGMEMLSRLP 505
T P G A G P R+ P S P P P + + P G S P
Sbjct: 810 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869
Query: 506 FPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTD-PGAQPLFFG 564
AG P G QG G G+ P + P+ G L G+ PG
Sbjct: 870 GRAGEP----GLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPG------- 918
Query: 565 VAQPQVSPHGTPSLPPPR-------VVGASPSESPLPSPA-----TNTAGSTCSSLSPMS 612
Q G P LP P GAS P P P T AG SP +
Sbjct: 919 ----QRGERGFPGLPGPSGEPGKQGAPGASGDRGP-PGPVGPPGLTGPAGEPGREGSPGA 973
Query: 613 SSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAF--- 669
P + G G + P P GSP P+ PT Q + +A
Sbjct: 974 DGPPGRDGAAG-VKGDRGETGAVGAPGAPGPPGSPGPAG------PTGKQGDRGEAGAQG 1026
Query: 670 ------PFPADGL-GAEGAFQCLEETPFPHE-GPEVGRG--GLQGFPRAPPPYPTHHFSL 719
P A G+ G +G E P E G + RG GLQG P P P
Sbjct: 1027 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGP-------- 1078
Query: 720 SSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSP 776
D+ S A R G + KDG PGP G P P
Sbjct: 1079 ---------------SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120
Score = 76.6 bits (187), Expect = 4e-13
Identities = 255/1080 (23%), Positives = 320/1080 (29%), Gaps = 221/1080 (20%)
Query: 426 ELAAPGPP-----PARLPQLWDPTAAPYPTPPGG---PLAATRSMFFNGQPSPGQRLCLP 477
++ PGP P + + P P P P G P G P P R P
Sbjct: 27 DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86
Query: 478 QSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAV 537
+ P P P P P G+ G E GG+Q LG GP P
Sbjct: 87 GTPGNPGPPG-PPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ--LGVMQGPMGPMG--PRG 141
Query: 538 RSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA 597
G+P + G +P GV+ P + P G P PP G E+ P A
Sbjct: 142 PPGPAGAPGPQGFQGNPGEPGEP---GVSGP-MGPRGPPG--PPGKPG-DDGEAGKPGKA 194
Query: 598 TNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPSAFFHPPTHPQETGSP----FPSPE 652
+P P + + PG G P E+GSP P P
Sbjct: 195 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 254
Query: 653 PPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGP-EVGRGGLQGFPRAPPP 711
P LP + PA GA G + P P P VG G GFP AP
Sbjct: 255 GPRGLPGE------RGRTGPAGAAGARGN----DGQPGPAGPPGPVGPAGGPGFPGAP-- 302
Query: 712 YPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPP 771
+ G AR +G Q G P
Sbjct: 303 ------------------------------------GAKGEAGPTGARGPEGAQGPRGEP 326
Query: 772 GLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP-FPLPAS 830
G P P PA A +G+ +G + P +A P FP P
Sbjct: 327 GTPGSPG----PAGA-------------SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369
Query: 831 DLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAG 890
+ T L G + Q+ P I + EP GP GP + G
Sbjct: 370 PPGPQG-------ATGPL-GPKGQTGEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEEG 420
Query: 891 VTPESKAPPPLPAATPDPQTPRPGDRGCPA-------RGRPKTRS-LGLAPTEADAPSQG 942
P + P + PG+RG P +G P R GLA + G
Sbjct: 421 KRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480
Query: 943 RQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERP-PPRPRRPRTQA 1001
R G G G G + P G RP PP P+ R Q
Sbjct: 481 RPGEPGLP----------GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ- 529
Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061
PG P P+ E + + LP R + G G
Sbjct: 530 PGVMGFPGPKGANG-----EPGKAGEKGLPGAPGLRGLPGKDGETGAA---------GPP 575
Query: 1062 REYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQ--------GPREDEPQK 1109
A E E P P G PG G G G K + + GPR +
Sbjct: 576 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 635
Query: 1110 PRKAARQEAGGDGAPANPEEPGGSRP----GPGRSPQARGP----SRSLETGAAAREGGP 1161
+ + G G P PG P GP P A+GP E GAA GP
Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI-AGP 694
Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSP- 1220
K DR V K P P T P E E P A +P
Sbjct: 695 K-GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPG 753
Query: 1221 ---------PAACAGEMGA--------------------SPGLLIPEQPPPSRHDTGTPK 1251
PA AG GA +PG P P + TG
Sbjct: 754 ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 813
Query: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPG-----GTQAPVSHNSKDPPARQPGEFLAPVANP 1306
P G+ P G++ PG +G PG G P + KD P G+ P
Sbjct: 814 PKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-SGPPGRA 872
Query: 1307 SSTACPKPSVLSSKISSFGCD-PAGFNRDPLGVPVAKKGPQPYSSPHSELFL----GPKD 1361
P+ + G D P+G P GPQ + + L G +
Sbjct: 873 GEPGLQGPAGPPGEKGEPGDDGPSGAEGPP--------GPQGLAGQRGIVGLPGQRGERG 924
Query: 1362 LAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTA--ETEPGRAASP 1419
G L +P + AP AS G P P PPG EPGR SP
Sbjct: 925 FPG--LPGPSGEPGKQGAPGAS-----------GDRGPPGPVGPPGLTGPAGEPGREGSP 971
Score = 72.8 bits (177), Expect = 6e-12
Identities = 255/1066 (23%), Positives = 335/1066 (31%), Gaps = 200/1066 (18%)
Query: 466 GQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAG 525
G+P + + P+ P P P P G + + A GP + G G G G
Sbjct: 38 GEPGDIKDIVGPKGPPGPQG---PAGEQGPRG-DRGDKGEKGAPGPRGRDGEPGTPGNPG 93
Query: 526 KTPGPREKLPAVRSSQGGSPALFTYNGMTDP--GAQPLFFGVAQPQVSPHGTPSLPPPRV 583
PGP P GG+ A G + GAQ GV Q + P G P PP
Sbjct: 94 P-PGPPG--PPGPPGLGGNFAAQMAGGFDEKAGGAQ---LGVMQGPMGPMG-PRGPP--- 143
Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQ- 642
P+ +P P +P P E + GP+GP PP P
Sbjct: 144 ---GPAGAPGPQG--------------FQGNPGEPG--EPGVSGPMGPRGPPGPPGKPGD 184
Query: 643 --ETGSPFPSPE--PPHSLPTHYQPEPAKAFPFPADGLGAEG--AFQCLEETPFPHEGPE 696
E G P + E PP P+ A+ FP G +G + L+ P
Sbjct: 185 DGEAGKPGKAGERGPPG-------PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG 237
Query: 697 V-GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGL 755
V G G G +P P L G
Sbjct: 238 VKGESGSPGENGSPGPMGPR--------------------------GLPGERGRTGPAGA 271
Query: 756 LLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTG 815
AR DG GPPG P P P A AG A G +
Sbjct: 272 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK--------GEAGPTGARGPEGAQGPR 323
Query: 816 FLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSS--FIDVFADEEP 873
P +P P AS + T+ + G + + P I + F P
Sbjct: 324 GEPGTPGSPGPAGAS----------GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 373
Query: 874 SGPRGP-----SSGHP----LKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924
G GP +G P K + G P+ + P P P P G RG ARG P
Sbjct: 374 QGATGPLGPKGQTGEPGIAGFKGEQG--PKGEPGPAGPQGAPGP-AGEEGKRG--ARGEP 428
Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLR-PRRN 983
P E AP G + G+ G A G+ G SGL P+
Sbjct: 429 GGVGPIGPPGERGAP--GNRGFPGQD-----------GLAGPKGAPGERGPSGLAGPKGA 475
Query: 984 DGLGERPPPRPRRPRTQ-APGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKAR 1042
+G P RP P A G P P+ P R PP
Sbjct: 476 NG----DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ------- 524
Query: 1043 GGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGP 1102
GA G+ ++ K E + E+ P PG RG G+ + GP
Sbjct: 525 -GARGQPGVMGFPGPKGANGE-----PGKAGEKGLPGAPGLRGLPGK-DGETGAAGPPGP 577
Query: 1103 REDEPQKPRKAARQEAGGDGAPANPEEPG-GSRPG----PGR--SPQARGPSRSL----E 1151
++ + A +G G P P PG G +PG PG +P GP E
Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637
Query: 1152 TGAAAREG--------------GPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEA 1197
G+ +G GPK A P+ P Q P + R +
Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP--GAQGPPGLQGMPGERGAAGIAGPK 695
Query: 1198 KEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSL- 1256
+ E P+ + R G +G PG P + + G P P+GS
Sbjct: 696 GDRGDVGEKGPEGAPGKDGGR----GLTGPIG-PPG---PAGANGEKGEVGPPGPAGSAG 747
Query: 1257 ANTAP--HGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAP-VANPSSTACPK 1313
A AP G + PG G PG P + A Q G+ AP PS P+
Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806
Query: 1314 -PSVLSSKISSFGCD-PAGFNRDP-----LGVPVAKKGPQPYSSPHSELFLGPKDLAGCF 1366
P+ ++ + G P G P +G P + P P P GPK G
Sbjct: 807 GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG-- 864
Query: 1367 LEELHPKPSARDAPPASSSCLCQDGE--DAGSLEPQLPRSPPGTAETEPGRA-ASPPTLE 1423
P R P GE + G P PPG R P
Sbjct: 865 ----DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 920
Query: 1424 SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPP 1469
FP LP +P G+ A+ D G P PP T P+ P
Sbjct: 921 GERGFPGLPGPSGEPGKQGAPGASGDRGPP-GPVGPPGLTGPAGEP 965
Score = 72.0 bits (175), Expect = 1e-11
Identities = 265/1132 (23%), Positives = 348/1132 (30%), Gaps = 234/1132 (20%)
Query: 6 PRGAPPPTMTGDLQPRQVASSPGHPSQP----PLEDNTPATRTTKGAR--EAGGQAQAME 59
PRG P P G P+ +PG P +P P+ P K EAG +A E
Sbjct: 139 PRGPPGPA--GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 196
Query: 60 LPEAQPRQARD-----------------------GELKPPSLRGQAPSSTPGKRGSP--- 93
P+ AR GE P ++G+ S +PG+ GSP
Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE--SGSPGENGSPGPM 254
Query: 94 --QTPPGRSPLQAPSRLAGRAEGSPPQRYILGI-----------------ASSRTKPTLD 134
+ PG P+ AG A G+ Q G A PT
Sbjct: 255 GPRGLPGERGRTGPAGAAG-ARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 313
Query: 135 ETPENPQLEAAQLPEVDTPQGPG----TGAPLRPGLPRTEAQPAAEELGFHRCF---QEP 187
PE Q E TP PG +G P G+P + A + F + P
Sbjct: 314 RGPEGAQ---GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370
Query: 188 PSSFTSTNYTSPSATPRPPA-------------PGPPQSRGTSPLQPGSYPEYQASGADS 234
P +T P P PGP +G PG E GA
Sbjct: 371 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA----PGPAGEEGKRGARG 426
Query: 235 WP-------PAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKP 287
P P E PG N G P + PKG+ P G++ +G +P
Sbjct: 427 EPGGVGPIGPPGERGAPG-NRGFPGQDGLAGPKGAPGERGPSGLAGP---KGANGDPGRP 482
Query: 288 FPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPG---- 343
+ G G +P A P+ VG A +P P +GQPG
Sbjct: 483 GEPGLPGARGLTG-------RPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 535
Query: 344 ----GLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP-----------PSAQ 388
G N +G PGA P D + P P PS
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595
Query: 389 DGLGSTRGPPSSLPQ---RHFPGQAYRASGVDTSPGPPDT-----ELAAPGPP----PAR 436
GL GPP + + PG+A G GP E +PG P
Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPGEA----GAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651
Query: 437 LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQR----LCLPQSAPLPWPQVLPTAR 492
LP + P GP A G P G+R + P+ + P
Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP--GERGAAGIAGPKGDRGDVGEKGPEGA 709
Query: 493 PSPHGMEMLSRL---PFPAG--GPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547
P G L+ P PAG G + + G G G+AG P E+ + G P
Sbjct: 710 PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER------GETGPPGP 763
Query: 548 FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPS-ESPL----PSPATNTAG 602
+ G QP G Q + G P P+ +P + P P A G
Sbjct: 764 AGFAGPPGADGQPGAKG-EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 822
Query: 603 STCSSLSPMSSSPANP--SSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEP---PHSL 657
++ P ++ P S+ PGP GPS P ++G P + EP +
Sbjct: 823 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 882
Query: 658 PTHYQPEPAKAFPFPADG----------LGAEGAFQCLEETPFPHEGPEVGRGGLQGFPR 707
P + EP P A+G G G E FP G G QG P
Sbjct: 883 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 942
Query: 708 AP----PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDG 763
A PP P L+ + + R S A R G + G
Sbjct: 943 ASGDRGPPGPVGPPGLTGPA----------GEPGREGSPGADGPPGRD--GAAGVKGDRG 990
Query: 764 HQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAAT 823
+ G PG P PP +P PA GD G P+ PS A
Sbjct: 991 ETGAVGAPGAPGPPGSPG-PAGPTG----------KQGDRGEAGAQGPMG----PSGPAG 1035
Query: 824 PFPLPASDLDMEDDAKLDSLITEALNGME-----YQSDNPEIDSSFIDVFADEEPSGPRG 878
+ D + L G P S PSGPRG
Sbjct: 1036 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1095
Query: 879 PSSGHPLKSKAGVT----------PESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRS 928
P K G P ++ PA P P PG G P G +
Sbjct: 1096 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP-PGPPGPPGPGIDMSAF 1154
Query: 929 LGLAPTE----------ADAPSQGRQQRRGK---QLKLFRKDLDSGGAAEGS 967
GL P E AD + G +Q + LK ++S + EGS
Sbjct: 1155 AGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGS 1206
Score = 63.9 bits (154), Expect = 3e-09
Identities = 123/507 (24%), Positives = 162/507 (31%), Gaps = 66/507 (13%)
Query: 3414 RGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473
+G P F+G+ PG PG EG P + +PG A PG PRG
Sbjct: 587 QGAPGPSGFQGL--PGPPGPPG---EGGKPGDQ---GVPGEAGAPG--LVGPRGERGFPG 636
Query: 3474 EGSLPALLHLCSEVAPSTTKGW--PETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFP 3531
E P L T G P+ P P G + P Q P +
Sbjct: 637 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP-----GAQGPPGLQGMPGERGAAGI 691
Query: 3532 AALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDAE-GKRAP 3589
A RGD G P + G GP+ P P GA G+ E G P
Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI---------GPPGPAGANGEKGEVGPPGP 742
Query: 3590 LVFSGKRRAPGARGRCA----------PDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHK 3639
+G R APG RG P + ++ E GP+G
Sbjct: 743 AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802
Query: 3640 GSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAK 3699
P G + K A P A FP A G + P + G P P K
Sbjct: 803 PGPQGPTGV-TGPKGARGAQGPPGATGFP----GAAGRVGPPG-SNGNPGPPGPPGPSGK 856
Query: 3700 PGPSSQGSGSPRPGTKTGGGSQ-PQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQA 3758
GP S PG G Q P G+ P+ P P P+ L A
Sbjct: 857 DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP---PGPQGL---AGQ 910
Query: 3759 KSCTKGPREAGEQGPHGSLGPKEK-------GESSTKRKKGQVPGPARSESVGSFGR--A 3809
+ P + GE+G G GP + G S + G V P + G GR +
Sbjct: 911 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970
Query: 3810 PSAPDKPPRTPRKQATPSR----VLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGK 3865
P A P R R + P P P ++ + G + +G
Sbjct: 971 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030
Query: 3866 AFPQGRPLLRPPK--RGTAVHGAEPAE 3890
+ P G ++ P+ RG EP E
Sbjct: 1031 SGPAGARGIQGPQGPRGDKGEAGEPGE 1057
Score = 61.2 bits (147), Expect = 2e-08
Identities = 170/653 (26%), Positives = 209/653 (32%), Gaps = 138/653 (21%)
Query: 2 PGER--PRGAPPPTMTGDLQPRQVASSPGHPSQPPLED-----NTPATRTTKGAREAGGQ 54
PG++ P A P + G R G P L+ TP T KGA G
Sbjct: 611 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 670
Query: 55 AQAMELPEAQPRQARDGELK---PPSLRG----QAPSSTPGKRGS-----PQTPPGRSPL 102
A P Q G P RG + P PGK G P PPG
Sbjct: 671 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG---- 726
Query: 103 QAPSRLAG-RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAP 161
P+ G + E PP G A +R P + E P G P
Sbjct: 727 --PAGANGEKGEVGPPGP--AGSAGARGAP-------------GERGETGPPGPAGFAGP 769
Query: 162 LRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAP----GPPQSRGT 216
P + QP A+ E G Q+ + PS P P P GP +RG
Sbjct: 770 -----PGADGQPGAKGEQG--EAGQKGDAGAPGPQ--GPSGAPGPQGPTGVTGPKGARGA 820
Query: 217 SPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPI----PKGSRPGGSPRGVS 272
PG+ A+G P N PG PP P P PKG+R P G +
Sbjct: 821 QG-PPGATGFPGAAGRVG--PPGSNGNPG-----PPGPPGPSGKDGPKGARGDSGPPGRA 872
Query: 273 FQFPFPALHGASTKPF----PADVAGHAFTNGPLVFAFHQPQGAWPEEAV----GTGPAY 324
+ P L G + P P D G + GP PQG + + G
Sbjct: 873 GE---PGLQGPAGPPGEKGEPGD-DGPSGAEGP-----PGPQGLAGQRGIVGLPGQRGER 923
Query: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384
P P PS P QG PG G + PG A P + + + P
Sbjct: 924 GFPGLPGPSGEPGKQGAPGASGDRGP-PGPVGPPGLTGPAGEPGREGSPGA------DGP 976
Query: 385 PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPP-PARLPQLWDP 443
P +DG +G PG +PGPP +PGP P
Sbjct: 977 PG-RDGAAGVKGDRGETGAVGAPG----------APGPP----GSPGPAGPTGKQGDRGE 1021
Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503
A P P GP A G P A P + L R G L
Sbjct: 1022 AGAQGPMGPSGPAGA------RGIQGPQGPRGDKGEAGEPGERGLKGHR----GFTGLQG 1071
Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPR-EKLPAVRSSQGGSPALFTYNGMTDPGAQPLF 562
LP GP G QGA G AG + GPR P S + G+ NG+ P P
Sbjct: 1072 LP----GPPGPSGDQGASGPAGPS-GPRGPPGPVGPSGKDGA------NGIPGPIGPPGP 1120
Query: 563 FGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSP 615
G + P G P P P P P P + S + L P P
Sbjct: 1121 RG-RSGETGPAGPPGNPGP------PGPPGPPGPGIDM--SAFAGLGPREKGP 1164
Score = 55.1 bits (131), Expect = 1e-06
Identities = 117/479 (24%), Positives = 144/479 (30%), Gaps = 72/479 (15%)
Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488
G G + E P R R PG+ PG PP P L + E A
Sbjct: 63 GPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKA 122
Query: 3489 PSTTKGWPETLERPVDPVTHP-IRGCELPSNHQECP-----PPSLSPF-PAALADGRGDC 3541
G + P+ P P G P Q P P P P G
Sbjct: 123 GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP 182
Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR-PGARG----QDAEGKRAPLVFSGKR 3596
DG +P G PGP + P LP G RG A+G+ G+
Sbjct: 183 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242
Query: 3597 RAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGC-------- 3648
+PG G P GPRG + T PAG
Sbjct: 243 GSPGENGSPGP-----------------------MGPRGLPGERGRTGPAGAAGARGNDG 279
Query: 3649 QSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSG 3708
Q P+ FP P A G P ARG E P PG
Sbjct: 280 QPGPAGPPGPVGPAGGPGFPGAP-GAKGEAGPTG-ARGPEGAQGPRGEPGTPGSPGPAGA 337
Query: 3709 SPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREA 3768
S PGT G++ + + A P P P P P+ K T P A
Sbjct: 338 SGNPGTDGIPGAKGSAGAPGI----AGAPGFPG-PRGPPGPQGATGPLGPKGQTGEPGIA 392
Query: 3769 ---GEQGPHGSLGPK----EKGESSTKRKKGQVPGPARSESVGSFGR--APSAPDKP--- 3816
GEQGP G GP G + + K+G P +G G AP P
Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452
Query: 3817 ----PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGR 3871
P+ + PS + K +P P PG R G A PQG+
Sbjct: 453 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP------GLPGARGLTGRPGDAGPQGK 505
Score = 54.3 bits (129), Expect = 2e-06
Identities = 116/469 (24%), Positives = 154/469 (32%), Gaps = 56/469 (11%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG G LP +R R G+A G D P P V
Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPP--------------GPV 290
Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA- 3546
P+ G+P + RG E + P SP PA + G + GA
Sbjct: 291 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 350
Query: 3547 --LERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFS-GKRRAPGARG 3603
P +PG PGP P GA+ P G +GQ E A G + PG G
Sbjct: 351 GSAGAPGIAGAPGFPGPRGPPG-PQGATGPL-GPKGQTGEPGIAGFKGEQGPKGEPGPAG 408
Query: 3604 -RCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP-----AGCQSSSKDR-- 3655
+ AP E+ E + G RG G+ P AG + + +R
Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA--PGNRGFPGQDGLAGPKGAPGERGP 466
Query: 3656 SAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTK 3715
S + P A P P + PG ARG A P+ K GPS RPG
Sbjct: 467 SGLAGPKGANGDPGRPGEPG---LPG--ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP- 520
Query: 3716 TGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP---REAGEQG 3772
PQ A GQ P FP A P +A K P G+ G
Sbjct: 521 ----PGPQGARGQ--------PGVMGFPGPKGANGE-PGKAGEKGLPGAPGLRGLPGKDG 567
Query: 3773 PHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP--PRTPRKQATPSRVL 3830
G+ GP + +R + PGP+ + + P KP P + P V
Sbjct: 568 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627
Query: 3831 PTKPK--PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPP 3877
P + P + P + + PG G + P G P + P
Sbjct: 628 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 676
Score = 46.2 bits (108), Expect = 6e-04
Identities = 107/391 (27%), Positives = 128/391 (32%), Gaps = 65/391 (16%)
Query: 3415 GGRQPFAFRGVRRP-GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS 3473
G P GV P GA G + P RV PGS PG PP P
Sbjct: 801 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP----GPSGK 856
Query: 3474 EGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA 3533
+G A + P G P L+ P P + + E PP P
Sbjct: 857 DGPKGAR----GDSGPPGRAGEPG-LQGPAGPPGEKGEPGDDGPSGAEGPPG-----PQG 906
Query: 3534 LADGRGDCALDGALERPENEASPGSPGPLLQ---QALPLGASLPR--PGARGQDAEGKRA 3588
LA RG L G +R E PG PGP + Q P GAS R PG G G
Sbjct: 907 LAGQRGIVGLPG--QRGER-GFPGLPGPSGEPGKQGAP-GASGDRGPPGPVGPP--GLTG 960
Query: 3589 PLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGC 3648
P G+ +PGA G P + E + GP G+ PAG
Sbjct: 961 PAGEPGREGSPGADG--PPGRDGAAGVKGDRGETGAVGAPGAPGPPGS------PGPAGP 1012
Query: 3649 QSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPG-PSSQGS 3707
DR A P+ P G ARG + P K + G P +G
Sbjct: 1013 TGKQGDRGEAGAQG-----PMGPSGPAG-------ARGIQGPQGPRGDKGEAGEPGERGL 1060
Query: 3708 GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERL--------------P 3753
R T G P SG + A+ PA PS P P P P
Sbjct: 1061 KGHRGFTGLQGLPGPPGPSGD---QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP 1117
Query: 3754 ARAQAKSCTKGPR-EAGEQGPHGSLGPKEKG 3783
+ +S GP G GP G GP G
Sbjct: 1118 PGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1148
Score = 44.7 bits (104), Expect = 0.002
Identities = 85/367 (23%), Positives = 112/367 (30%), Gaps = 45/367 (12%)
Query: 3547 LERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCA 3606
+ +P + G PG + P G P+ A Q G R G++ APG RGR
Sbjct: 28 VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD---KGEKGAPGPRGR-- 82
Query: 3607 PDHFQEDHLLQKEKEVSSSHMVSEGGPRG-TFHKGSATKPAGCQSSSKDRSAASTPSKAL 3665
+ E + GP G G A + D A +
Sbjct: 83 ------------DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVM 130
Query: 3666 KFPVHPRKAVGSLAP----------GELARGTENGMK-PATPKAKPGPSSQGSGSPRPGT 3714
+ P+ P G P G E G+ P P+ PGP + G
Sbjct: 131 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG- 189
Query: 3715 KTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQA-----KSCTKGPREAG 3769
K G + P Q TP P P A+ +A K + P E G
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249
Query: 3770 EQGPHGSLG-PKEKGESSTKRKKGQ-----VPGPARSES-VGSFGRA--PSAPD-KPPRT 3819
GP G G P E+G + G PGPA VG G P AP K
Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 309
Query: 3820 PRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKR 3879
P P + +P + P P + G K G G P P+
Sbjct: 310 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369
Query: 3880 GTAVHGA 3886
GA
Sbjct: 370 PPGPQGA 376
Score = 40.0 bits (92), Expect = 0.046
Identities = 56/236 (23%), Positives = 68/236 (28%), Gaps = 30/236 (12%)
Query: 3679 APGELAR----GTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA 3734
APG R GT P P PGP G + GG + QL
Sbjct: 76 APGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF---AAQMAGGFDEKAGGAQLG--VM 130
Query: 3735 TTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPK-------EKGESST 3787
P P P P P P + P E G GP G GP + GE+
Sbjct: 131 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 190
Query: 3788 KRKKGQVPGPARSESVGSFGRAPSAPDKPPRT-------PRKQATPSRVLPTKPKPNSQN 3840
K G+ GP + F P P + +A V P
Sbjct: 191 PGKAGE-RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249
Query: 3841 KPRP------PPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAE 3890
P P P R G + G+ P G P P G GA A+
Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 305
Score = 38.9 bits (89), Expect = 0.10
Identities = 101/428 (23%), Positives = 128/428 (29%), Gaps = 68/428 (15%)
Query: 3419 PFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILS-EGSL 3477
P F G PGA GQ E ++ PG P P P+G + + +G+
Sbjct: 763 PAGFAGP--PGADGQPGAKGEQGEAGQKGDAGAPG--PQGPSGAPGPQGPTGVTGPKGAR 818
Query: 3478 PALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADG 3537
A P G+P R P ++ G P P + +
Sbjct: 819 GAQ-------GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 871
Query: 3538 RGDCALDGALERPENEASPGSPGPLLQQALPLGASLPR-------PGARGQDA-EGKRAP 3589
G+ L G P + PG GP + P L PG RG+ G P
Sbjct: 872 AGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 931
Query: 3590 LVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649
GK+ APGA G + GP G T PAG
Sbjct: 932 SGEPGKQGAPGASG--------------------------DRGPPGPVGPPGLTGPAGEP 965
Query: 3650 SSSKDRSAASTPSK----ALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQ 3705
A P + +K AVG APG A G PA P K G +
Sbjct: 966 GREGSPGADGPPGRDGAAGVKGDRGETGAVG--APG--APGPPGSPGPAGPTGKQGDRGE 1021
Query: 3706 GS--GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTK 3763
G P G P + A P + R R Q
Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE-----RGLKGHRGFTGLQGLPGPP 1076
Query: 3764 GPR----EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA-PSAPDKPPR 3818
GP +G GP G GP S K +PGP G GR+ + P PP
Sbjct: 1077 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP--GPRGRSGETGPAGPPG 1134
Query: 3819 TPRKQATP 3826
P P
Sbjct: 1135 NPGPPGPP 1142
Score = 37.7 bits (86), Expect = 0.23
Identities = 36/111 (32%), Positives = 43/111 (38%), Gaps = 17/111 (15%)
Query: 3187 PGGLEGSSAVAHLLNSITE------PAPKHHRGKRSAGKAAGSPGDPW-----GQEGEAK 3235
P GL G + L E P P GK+ A A+G G P G G A
Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA- 962
Query: 3236 KDSPGERAKPRARSTPSNPDGAA--TPDSASATALADAGSPGPPRTTPSPS 3284
PG P A P DGAA D A+ G+PGPP +P P+
Sbjct: 963 -GEPGREGSPGADGPPGR-DGAAGVKGDRGETGAVGAPGAPGPP-GSPGPA 1010
Score = 35.4 bits (80), Expect = 1.1
Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNP-DGAATPDSAS 3264
P K HRG A G G P G +GE+ SPGE P P + T + +
Sbjct: 215 PGVKGHRGYPGLDGAKGEAGAP-GVKGES--GSPGENGSPGPMGPRGLPGERGRTGPAGA 271
Query: 3265 ATALADAGSPGP--PRTTPSPSPDPWAGGEP 3293
A A + G PGP P P+ P G P
Sbjct: 272 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAP 302
Score = 35.0 bits (79), Expect = 1.5
Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 22/96 (22%)
Query: 3203 ITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSP-------GERAKPRARSTPSNPD 3255
+ +P PK +G+ K P P G +G A + P GE+ P R P
Sbjct: 28 VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP- 86
Query: 3256 GAATPDSASATALADAGSPGPPRTTPSPSPDPWAGG 3291
TP G+PGPP P P P GG
Sbjct: 87 --GTP-----------GNPGPPG-PPGPPGPPGLGG 108
Score = 32.7 bits (73), Expect = 7.3
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 3205 EPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSAS 3264
+P K +G+ AG+PG P G G +PG + P + P GA P A+
Sbjct: 775 QPGAKGEQGEAGQKGDAGAPG-PQGPSG-----APGPQG-PTGVTGPKGARGAQGPPGAT 827
Query: 3265 ATALADAGSPGPPRTTPSPSP 3285
A AG GPP + +P P
Sbjct: 828 GFPGA-AGRVGPPGSNGNPGP 847
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 94.4 bits (233), Expect = 2e-18
Identities = 252/1073 (23%), Positives = 341/1073 (31%), Gaps = 240/1073 (22%)
Query: 4 ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEA 63
E P G PP + ++ SP PP +P + A GQ + P+
Sbjct: 1775 ESPVGLPPE------EEDKLTRSPFEIISPPA---SPPEMVGQRVPSAPGQESPIPDPKL 1825
Query: 64 QPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILG 123
P E PS P P R P P SP P A E P + G
Sbjct: 1826 MPHMKN--EPTTPSWLADIPPWVPKDRPLPPAP--LSPAPGPPTPA--PESHTPAPFSWG 1879
Query: 124 IASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRC 183
A D Q AA+L P P G R E + AE
Sbjct: 1880 TAE------YDSVVAAVQEGAAELE--GGPYSP-LGKDYRKAEGEREEEGRAEAPDKSSH 1930
Query: 184 FQEPPSSFTSTNYTSPSATP---RPPAPGPPQSR-------------GTSPLQPGSYPEY 227
+ P + S T P T R P P P + G P P P
Sbjct: 1931 SSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPL 1990
Query: 228 QASGADSWPP--AAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGAST 285
A+G WPP + + + G N PI S +P F + AL G +
Sbjct: 1991 GAAG--DWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPT-----FSYAALAGPTV 2043
Query: 286 KPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAV-GTGPAYPL--------PTQPAPSPLP 336
P P GP + P P + GP+ PL P + +PSP
Sbjct: 2044 PPRPEP--------GPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKE 2095
Query: 337 CYQGQPGGLNRHSDLS-GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTR 395
+ S+L GA P +P P + + PE L S
Sbjct: 2096 SGRSHWDDSTSDSELEKGAREQPEKEAQSPSP-PHPIPMGSPTLWPETEAHVSPPLDSHL 2154
Query: 396 GPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT----- 450
GP + P FP A+ S + P P +LP +P +AP +
Sbjct: 2155 GP--ARPSLDFPASAFGFSSLQ--------------PAPPQLPSPAEPRSAPCGSLAFSG 2198
Query: 451 ------PPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRL 504
PG P + +P LPQ LP+ PS G +LS L
Sbjct: 2199 DRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQ---------LPS--PSSPGAPLLSNL 2247
Query: 505 PFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG 564
P PA +G S A + R P++ +++ S G DPG +P
Sbjct: 2248 PRPASPALSEGSSSEATTPVISSVAERFS-PSLEAAEQES-------GELDPGMEP---- 2295
Query: 565 VAQPQVSPHGTPSLPPPRVVGASPSESPLP-SPATNTAGSTCSSLSPMSSSPANPSSEES 623
+ H L P + A P+ L +PA + G + P + ++E+
Sbjct: 2296 ------AAHSLWDLTP--LSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEK- 2346
Query: 624 QLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQ 683
PS F P G SP PP P + E A A P G EGA +
Sbjct: 2347 -------PSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAER 2399
Query: 684 CLE-ETPFPHEGPEVGRGGLQGFPRAPPPY-----------PTHHFSLSSASLDQLDVLL 731
+T E P GG G P + P P H S S L+ L
Sbjct: 2400 SSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSF--LNPPL 2457
Query: 732 TCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLL 791
DR+ S+ L R R + G PG G P P P A
Sbjct: 2458 PPSIDDRDLSTEEVRLVGRG------GRRRVG---GPGTTGGPCPVTDETPPTSASD--- 2505
Query: 792 SHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGM 851
+G +Q++ D P T PS+ A +A LDS
Sbjct: 2506 --------SGSSQSDS-DVPPETEECPSITA--------------EAALDS--------- 2533
Query: 852 EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911
+ D F+ V SG P GH PPPLP P P P
Sbjct: 2534 -------DEDGDFLPVDKAGGVSGTHHPRPGHD-------------PPPLPQPDPRPSPP 2573
Query: 912 RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971
RP + +A E + GR +R ++ K+ + G
Sbjct: 2574 RP--------------DVCMADPEGLSSESGRVERLREKEKVQGR----------VGRRA 2609
Query: 972 GGRASGLRP-RRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETR 1023
G+A P RR D G+R P + P +A SRA P PR + P E +
Sbjct: 2610 PGKAKPASPARRLDLRGKRSPTPGKGPADRA--SRAPPRPRSTTSQVTPAEEK 2660
Score = 59.7 bits (143), Expect = 6e-08
Identities = 215/937 (22%), Positives = 301/937 (32%), Gaps = 160/937 (17%)
Query: 1457 ADPPQ---KTVPSDP------PYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVV 1507
A PP+ + VPS P P P + + P PS D+ + PP +
Sbjct: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPA-PLS 1858
Query: 1508 PGAAPSLPGKGSGCSVALMSHLSEDE---LEIQKLVTELE-------------SQLQRSK 1551
P P P S +E + +Q+ ELE ++ +R +
Sbjct: 1859 PAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREE 1918
Query: 1552 DTRG-APRELAEAESVGRVELGTGTEPPSQRRTCQ---ATVPHEDTFSAADLTRVGESTA 1607
+ R AP + + + V T P Q Q P E +F AD+ T
Sbjct: 1919 EGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLT- 1977
Query: 1608 HREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQ 1667
G A T E G G WP S A A+++L S P SP+
Sbjct: 1978 ---GLGPACPTREPPLGA-AGDWPPCLSTKEAAAGRNTSAEKELSS--PISPKSLQSD-T 2030
Query: 1668 PVQKAGASKTGLCQAEGDSRPPQDVCLPEP---------SKQPGPQLDAGSLAKCSPDQE 1718
P A + P + L P SK P P L+ G++ CSPD+
Sbjct: 2031 PTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLN-GNILSCSPDRR 2089
Query: 1719 LSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGA-----PAPEAFGSPAV 1773
PK + +S L E G +QP + A P P GSP +
Sbjct: 2090 SPSPKESGRSHWDDSTSDSEL-----------EKGAREQPEKEAQSPSPPHPIPMGSPTL 2138
Query: 1774 ------HLAPDL-AFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEG 1826
H++P L + G P LD F AS A G S+ + P+ P
Sbjct: 2139 WPETEAHVSPPLDSHLGPARPSLD----FPAS----AFGFSSLQPAPPQLPSPAEP---- 2186
Query: 1827 NEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQL--------- 1877
AP G SL R L P P P + ++ P+L + QL
Sbjct: 2187 -RSAPCG--SLAFSGDRALALAPGP-PTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAP 2242
Query: 1878 ---QLPGPGVAKSKDGILGLQELTPAAQS-PPRVNPSGLEGGTVEGGKVACGPAQGSPGG 1933
LP P +G + TP S R +PS LE E G++ G +
Sbjct: 2243 LLSNLPRPASPALSEG-SSSEATTPVISSVAERFSPS-LEAAEQESGELDPGMEPAAHSL 2300
Query: 1934 VQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNA- 1992
+T L L L L A G L S T+ +
Sbjct: 2301 WDLTPLSPAPPASLDL-------ALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVP 2353
Query: 1993 SPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPS------PPSPNRESLALALTAAH 2046
S A GPTE + G A + EEA P+ P R S L +
Sbjct: 2354 SEDCAANGPTETS---PNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPE 2410
Query: 2047 S----RSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPL 2102
GS G P ++SP + P P G+L+ +P +P S+
Sbjct: 2411 QPVCPAGGSGG--PPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPP----LPPSIDD- 2463
Query: 2103 PREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAE 2162
D T R G G + P P P + P +D + +D+
Sbjct: 2464 --RDLSTEEVRLVGRGGRRRVGGPGTTGGPCP-----VTDETPPTSASDSGSSQSDSDVP 2516
Query: 2163 DSPVAPPSLTTS------------PCDPKEALAGCLLQGEGS-----PLEDPSSWPPGSV 2205
PS+T P D ++G G P DP PP
Sbjct: 2517 PETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPP--- 2573
Query: 2206 SAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPT 2265
C + + R+ KEK+ GR +P A SP+ + G S PT
Sbjct: 2574 RPDVCMADPEGLSSESGRVERLREKEKVQGRVGR-RAPGKAKPASPARRLDLRGKRS-PT 2631
Query: 2266 GDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302
+ A R P P+ R P GHS S
Sbjct: 2632 PGKGPADRASRAP-PRPRSTTSQVTPAEEKDGHSPMS 2667
Score = 54.7 bits (130), Expect = 2e-06
Identities = 115/460 (25%), Positives = 170/460 (36%), Gaps = 79/460 (17%)
Query: 3434 KARALEGTLPSKRRRVAMPG-SAPGPGEDRPPPRGSSPILSEGS-----LPALLHLCSEV 3487
KA +L+ +LP +P S+PG PR +SP LSEGS P + +
Sbjct: 2222 KAPSLDSSLPQ------LPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERF 2275
Query: 3488 APSTTKGWPET--LERPVDPVTHPIRGCELPSNHQECPPPS----LSPFPAALADGRGDC 3541
+PS E+ L+ ++P H + S PP S L+P P+ D GD
Sbjct: 2276 SPSLEAAEQESGELDPGMEPAAHSLWDLTPLS---PAPPASLDLALAPAPSLPGD-MGDG 2331
Query: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR------PGARGQDAEGKRAPLVFSGK 3595
L LE +EA+ P P + A+ P PG AE + A + +
Sbjct: 2332 ILPCHLEC--SEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWE 2389
Query: 3596 RRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR 3655
R GA A + D LL E+ V + GGP + P GC + +
Sbjct: 2390 R---GAWPEGAERSSRPDTLLSPEQPVCPAG--GSGGPPSSASPEVEAGPQGCATEPRPH 2444
Query: 3656 SAASTPSKALKFPVHPRKAVGSLAPGEL------------ARGTENGMKPATPKAKPGPS 3703
+PS L P+ P L+ E+ GT G P T + P S
Sbjct: 2445 RGELSPS-FLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPP-TS 2502
Query: 3704 SQGSGSPRPGTKTGGGSQPQP---ASGQLQSE--------------TATTPAKPSF-PSR 3745
+ SGS + + ++ P A L S+ + T +P P
Sbjct: 2503 ASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPP 2562
Query: 3746 SPAPERLPARAQAKSCTKGPRE-AGEQGPHGSLGPKEKGESSTKRK---KGQVPGPARSE 3801
P P+ P+ + C P + E G L KEK + R+ K + PAR
Sbjct: 2563 LPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRL 2622
Query: 3802 SVGSFGRAPSAPDKPP------RTPRKQATPSRVLPTKPK 3835
+ G+ P K P PR ++T S+V P + K
Sbjct: 2623 DLR--GKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEK 2660
Score = 47.4 bits (111), Expect = 3e-04
Identities = 178/777 (22%), Positives = 249/777 (32%), Gaps = 146/777 (18%)
Query: 3166 LREHAVRFARRGQARRSLGDLPG-GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSP 3224
LREHA R + P GLE +A + + P + + RS + P
Sbjct: 1742 LREHATRSPWASDFKDFQESSPQKGLEVERWLAE--SPVGLPPEEEDKLTRSPFEIISPP 1799
Query: 3225 GDPWGQEGEAKKDSPGERAK-------PRARSTPSNPDGAA-----TPDSASATALADAG 3272
P G+ +PG+ + P ++ P+ P A P +
Sbjct: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSP 1859
Query: 3273 SPGPPRTTP---SPSPDPWAGGE------------PLLQATPVHEACKD----------- 3306
+PGPP P +P+P W E L+ P KD
Sbjct: 1860 APGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEE 1919
Query: 3307 -----PSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGE---------- 3351
P + H + P+ K A P++ R P YP+
Sbjct: 1920 GRAEAPDKSSH--SSKVPEASKSH---ATTEPEQTEPEQREPTPYPDERSFQYADIYEQM 1974
Query: 3352 LLAHLGGAHGLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNK 3411
+L LG A E P C + A + N T A+KE K
Sbjct: 1975 MLTGLGPACPTREPPLGAAGDWPPC---------LSTKEAAAGRN-TSAEKELSSPISPK 2024
Query: 3412 HLRGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRP--PPRGSS 3469
L+ F++ + P P + PG + P P PPR +
Sbjct: 2025 SLQSDTPTFSYAALAGPTVPPRPE----------------PGPSMEPSLTPPAVPPR--A 2066
Query: 3470 PILSEGSLPALLHLCSEVAPSTTKGWPETLERP-VDPVTHPIR----GCELPSNHQECP- 3523
PILS+G P L +P P+ R D T E P + P
Sbjct: 2067 PILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPS 2126
Query: 3524 PPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA 3583
PP P + + + L+ A P P A + P P A
Sbjct: 2127 PPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFP--ASAFGFSSLQPAPPQLPSPA 2184
Query: 3584 EGKRAP---LVFSGKRR---APGARGRCAPDHFQEDHLLQKEKEVSSS--HMVSEGGPRG 3635
E + AP L FSG R APG R D + E + K + SS + S P G
Sbjct: 2185 EPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLE---VTKAPSLDSSLPQLPSPSSP-G 2240
Query: 3636 TFHKGSATKPAGCQSSSKDRSAASTP---SKALKFPVHPRKAVGSLAPGELARGTE---- 3688
+ +PA S S A+TP S A +F P GEL G E
Sbjct: 2241 APLLSNLPRPASPALSEGSSSEATTPVISSVAERF--SPSLEAAEQESGELDPGMEPAAH 2298
Query: 3689 -----NGMKPATPKA-----KPGPS---SQGSGSPRPGTKTGGGSQPQPASGQLQSE--T 3733
+ PA P + P PS G G + + +P+ Q+ SE
Sbjct: 2299 SLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCA 2358
Query: 3734 ATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQ 3793
A P + S PAP + +A +C R A +G S P T Q
Sbjct: 2359 ANGPTETSPNPPGPAPAK-AENEEAAACPAWERGAWPEGAERSSRP------DTLLSPEQ 2411
Query: 3794 VPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQR 3850
PA GS G SA + P+ AT R + P+ N P PP + R
Sbjct: 2412 PVCPAG----GSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDR 2464
Score = 43.1 bits (100), Expect = 0.005
Identities = 178/789 (22%), Positives = 246/789 (31%), Gaps = 176/789 (22%)
Query: 2026 PTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAAC 2085
PT PP L+ + +G + SSP K L + D+P S LA
Sbjct: 1984 PTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQS--DTPTFSYAALAG- 2040
Query: 2086 APSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWA 2145
PT + P P P PS + + P PP +L+CSP
Sbjct: 2041 ---PT--------VPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRR 2089
Query: 2146 PLEEADGVQATTDTGAEDSPV------APPSLTTSPCDPKEALAGCLLQGEGSPLEDPSS 2199
+ ++ D DS + P SP P P+ P+
Sbjct: 2090 SPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPI-----------PMGSPTL 2138
Query: 2200 WP--PGSVSAVTCTHSGDTPKDSTLRIPEDS-RKEKLWESPGRATSP------------- 2243
WP VS +H G P +L P + L +P + SP
Sbjct: 2139 WPETEAHVSPPLDSHLG--PARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAF 2196
Query: 2244 --PLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPG-PDPQSRGAPPHTNPDRMPRGHSS 2300
A A++P R LP P P S GAP +N +PR
Sbjct: 2197 SGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSN---LPR---- 2249
Query: 2301 YSPSNTARLGHREGQAVTAVPTE-----PPTLQGAGPDSPACLEGEMGTSSKEPEDPGTP 2355
P++ A +A T V + P+L+ A +S GE+ DPG
Sbjct: 2250 --PASPALSEGSSSEATTPVISSVAERFSPSLEAAEQES-----GEL--------DPGME 2294
Query: 2356 ETGRSGATKMPRVTCPSTGLGLGRTTAPS---------------------STASDFQSDS 2394
S P P L L APS S FQ S
Sbjct: 2295 PAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPS 2354
Query: 2395 PQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQW-----KGQAPHGPVTCE-- 2447
N +T P GP K + PA E G W + P ++ E
Sbjct: 2355 EDCAANGPTETSPNPP-GPAPAKAENEEAAACPA-WERGAWPEGAERSSRPDTLLSPEQP 2412
Query: 2448 VCAASFRSGPGLSRHK---------ARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPP 2498
VC A GP S A + RPH G E SP+ L PL P
Sbjct: 2413 VCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRG---ELSPSFL--NPPLPPSIDDRDLS 2467
Query: 2499 RKKSHRV--SGKERPN--HSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHE 2554
++ V G+ R + G P VT P + + GS S PP TE
Sbjct: 2468 TEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASD----SGSSQSDSDVPPE-TEEC 2522
Query: 2555 VDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSP------------------ 2596
+ A+ D + + P P D P
Sbjct: 2523 PSITAEAAL---DSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCM 2579
Query: 2597 SHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGG 2656
+ EG S++ R RLRE+ + GR R +P A ASP+ L + G
Sbjct: 2580 ADPEGLSSESG---RVERLREKEKV--------QGRVGRRAPGKAK-PASPARRLDLRG- 2626
Query: 2657 PEADGEQPPRLATLGPGVMEGA--AETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGE 2714
R T G G + A A + + T A++ G + G ++G G
Sbjct: 2627 --------KRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGP 2678
Query: 2715 QPTGQKGAS 2723
KG+S
Sbjct: 2679 MALSSKGSS 2687
Score = 41.6 bits (96), Expect = 0.016
Identities = 108/439 (24%), Positives = 144/439 (32%), Gaps = 59/439 (13%)
Query: 1089 RGEKRKEVELTQGPREDEPQKP--RKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGP 1146
R E +E + P P+ P K G+ +P+ S GRS
Sbjct: 2046 RPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDST 2105
Query: 1147 SRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEE------------TRPSLDFP 1194
S S E ARE K A PS P+ PT +E RPSLDFP
Sbjct: 2106 SDS-ELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFP 2164
Query: 1195 QEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTP-KPS 1253
A + + + P E RS P G L P P +RHD +
Sbjct: 2165 ASAFGFSSLQPAPPQLPSPAEP-RSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKA 2223
Query: 1254 GSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPK 1313
SL ++ P SP+ LL +P A P ++ VA S +
Sbjct: 2224 PSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTP--VISSVAERFSPSLEA 2281
Query: 1314 PSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFL------ 1367
S ++ G +PA + L P++ P + P D+ L
Sbjct: 2282 AEQESGELDP-GMEPAAHSLWDL-TPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLEC 2339
Query: 1368 -EELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPG-------RAASP 1419
E KPS P S C + P P P AE E R A P
Sbjct: 2340 SEAATEKPSPFQVP--SEDCAANGPTET---SPNPPGPAPAKAENEEAAACPAWERGAWP 2394
Query: 1420 PTLESSS-----LFPDLPV----DRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPY 1470
E SS L P+ PV PP S S ++G P CA P+ P+
Sbjct: 2395 EGAERSSRPDTLLSPEQPVCPAGGSGGPP--SSASPEVEAG-PQGCATEPR-------PH 2444
Query: 1471 PSFLLLEEVSPMLPSHFPD 1489
L ++P LP D
Sbjct: 2445 RGELSPSFLNPPLPPSIDD 2463
Score = 40.8 bits (94), Expect = 0.027
Identities = 207/951 (21%), Positives = 297/951 (31%), Gaps = 252/951 (26%)
Query: 1101 GPREDEPQK--PRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAARE 1158
GP P+ P + A D A +E G SP + ++ G E
Sbjct: 1862 GPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKA--EGEREEE 1919
Query: 1159 GGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL- 1217
G + D+ S + K VP +++ T P P++ + +E + + E +
Sbjct: 1920 GRAEAPDKSSHSSK----VPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMM 1975
Query: 1218 ----------RSPPAACAGEM---------------GASPGLLIPEQPPPSRHDTGTPKP 1252
R PP AG+ A L P P + DT T
Sbjct: 1976 LTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSY 2035
Query: 1253 SGSLANTAPHGSSPTPGVGSLLGGPG-GTQAPVSHNSKDPPARQPGEFLAPVANPSSTAC 1311
+ T P P P + L P +AP+ PP G L+ + S
Sbjct: 2036 AALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLN--GNILSCSPDRRS--- 2090
Query: 1312 PKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELH 1371
PS S S + + + +K Q S PH P L
Sbjct: 2091 --PSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSP---------TLW 2139
Query: 1372 PKPSARDAPPASSSCLCQDGEDAGSLEPQL--PRSPPGTAETEPGRAASPPTLESSSLFP 1429
P+ A +PP S G P L P S G + +P +PP L S
Sbjct: 2140 PETEAHVSPPLDS--------HLGPARPSLDFPASAFGFSSLQP----APPQLPS----- 2182
Query: 1430 DLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPD 1489
P + P GSL+ + D L A P + L+ P LPS P
Sbjct: 2183 --PAEPRSAPC-GSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPS--PS 2237
Query: 1490 LSGGKVLSKTCPPERTVVPGAAPSL-PGKGSGCSVALMSHLSEDELEIQKLVTELESQLQ 1548
G +LS P A+P+L G S + ++S ++E
Sbjct: 2238 SPGAPLLSNLPRP-------ASPALSEGSSSEATTPVISSVAE----------------- 2273
Query: 1549 RSKDTRGAPR-ELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTA 1607
R +P E AE ES EL G EP + S DLT + S A
Sbjct: 2274 -----RFSPSLEAAEQES---GELDPGMEPAAH--------------SLWDLTPL--SPA 2309
Query: 1608 HREGAESAVATVEAVQGRPG-GTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHF 1666
+ A+A ++ G G G PC L C++ +PF +
Sbjct: 2310 PPASLDLALAPAPSLPGDMGDGILPCH----------LECSEAATEKPSPFQVPSED--- 2356
Query: 1667 QPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKE 1726
C A G + + P P+K + A C + ++P+ E
Sbjct: 2357 -------------CAANGPTETSPNPPGPAPAKAENEE-----AAACPAWERGAWPEGAE 2398
Query: 1727 AASSQESEDSLRLLPCEQRGGFLP--------EPG-----TADQPHRGAPAPEAFGSPAV 1773
+S ++ S C G P E G T +PHRG +P P
Sbjct: 2399 RSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLP 2458
Query: 1774 HLAPDLAFQ---------------------GDGAPPLDATWPFGASPSHAAQGHSAGRAG 1812
D G P D T P AS S ++Q S
Sbjct: 2459 PSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDS----- 2513
Query: 1813 GHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSP 1872
+ P E P+ + + +PV VS TH R DP P
Sbjct: 2514 -DVPPE--------TEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDP---P 2561
Query: 1873 PIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPR-----VNPSGL--EGGTV----EGGK 1921
P+ Q P P SPPR +P GL E G V E K
Sbjct: 2562 PLPQ---PDP------------------RPSPPRPDVCMADPEGLSSESGRVERLREKEK 2600
Query: 1922 VACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQ 1972
V + +PG + PA +L L G+ T G+G A++
Sbjct: 2601 VQGRVGRRAPGKAK----PASPARRLDLR--------GKRSPTPGKGPADR 2639
Score = 38.5 bits (88), Expect = 0.13
Identities = 60/276 (21%), Positives = 93/276 (33%), Gaps = 38/276 (13%)
Query: 2 PGERPRG-APPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTT-------KGAREAGG 53
PGE G A ++ D ++AS P PS PP +TP ++ + +EA
Sbjct: 972 PGEPALGEAEERCLSPDDSTVKMASPP--PSGPPSATHTPFHQSPVEEKSEPQDFQEADS 1029
Query: 54 QAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAE 113
P A + +KP G + PP RSP +A+
Sbjct: 1030 WGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEE-------KVPPPRSP---------QAQ 1073
Query: 114 GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG----LPRT 169
+P + I T T+ P + ++ E P GP GA PG LP+
Sbjct: 1074 EAP-----VNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQE 1128
Query: 170 EAQPAAEEL---GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPE 226
+P +E+ E S + + SP + P P P L +PE
Sbjct: 1129 PGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPE 1188
Query: 227 YQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGS 262
S + E+ + V + P G+
Sbjct: 1189 VSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGT 1224
Score = 37.7 bits (86), Expect = 0.23
Identities = 184/849 (21%), Positives = 276/849 (32%), Gaps = 155/849 (18%)
Query: 1502 PERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKD---TRGAPR 1558
P T + G PS+PG G E ++ ++LV E+ + Q SKD GA
Sbjct: 568 PPSTAIQGTPPSVPGLGQ----------EEHVMKEKELVPEVPEE-QGSKDRGLDSGAET 616
Query: 1559 ELAEAESVGRVELGTGTEPPSQRRTCQATVPH--EDTFSAADLTRVGE---STAHREGAE 1613
E E ++ + P + + + P ED A+L + E S E A
Sbjct: 617 E-EEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDAT 675
Query: 1614 SAVATVEAVQGRPGGTWPCPASFHPGHAALL----PCAQEDLVSGAPFSPRGANFHFQPV 1669
A + P P G L P + L + +P GA H +
Sbjct: 676 KAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYI 735
Query: 1670 QK---AGASKTGLC--------QAEGDSRPPQ------DVCLPE-----PSKQPGPQLDA 1707
Q G S+T + E PP+ D+ PE + QP
Sbjct: 736 QDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVP 795
Query: 1708 GSLAKC--SPDQELSFPKNKEAASSQESE---DSLRLLPCEQRGGFLPEPGTADQPHRGA 1762
+ K +P+ EL++P N AA E E + + C++ F A
Sbjct: 796 ATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSSF-------------A 842
Query: 1763 PAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRP 1822
+ S A AP G + LD +S + A QG + G + PT+
Sbjct: 843 TSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLE 902
Query: 1823 GFEGNEFAPAGASSLTAP---------RGREAWLVPVPSPACVSNTHPSRR--SQ--DPA 1869
+G + P S+T +G +N S + SQ P
Sbjct: 903 EDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPV 962
Query: 1870 LSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQG 1929
S P L P + ++++ L + T SPP PSG T P
Sbjct: 963 FSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPP---PSGPPSATHT-------PFHQ 1012
Query: 1930 SPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTAN-------------QLQPE 1976
SP V+ + P Q EAD W G ++T G G + L+ E
Sbjct: 1013 SP--VEEKSEP-----QDFQEADS-W---GDTKRTPGVGKEDAAEETVKPGPEEGTLEKE 1061
Query: 1977 NGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRE 2036
V P + + LTG T + L + + E EPT P E
Sbjct: 1062 EKVPPPRSPQAQEAPVNIDEGLTGCT---IQLLPAQDKAIVFEIMEAGEPT--GPILGAE 1116
Query: 2037 SLALALTAAHSRSGSEG-----RTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTS 2091
+L L G R P+R+ SP A S+ L+ PSP +
Sbjct: 1117 ALPGGLRTLPQEPGKPQKDEVLRYPDRSLSP-----------EDAESLSVLS--VPSPDT 1163
Query: 2092 AAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEAD 2151
A P P + R P Q L+ S EE+
Sbjct: 1164 ANQEPTPKSPCGLTEQYLHKDRWP-------------EVSPEDTQSLSLS------EESP 1204
Query: 2152 GVQATTDTGAED-SPVAPPSLTTSPCDPKEALAGCLLQGEG-SPLEDPSSWPPGSVSAVT 2209
+ + D ++ SP + +L + + G L+Q E S P S P + +
Sbjct: 1205 SKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATAS 1264
Query: 2210 CTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEA 2269
G T + I +DS K S ++P G P TP +
Sbjct: 1265 PPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFS 1324
Query: 2270 QAGRGLPGP 2278
++ LPGP
Sbjct: 1325 KSPESLPGP 1333
Score = 35.4 bits (80), Expect = 1.1
Identities = 57/238 (23%), Positives = 84/238 (35%), Gaps = 36/238 (15%)
Query: 36 EDNTPATRTTKGAREAGGQAQAMELPEAQPR---QARDGELKPPSLRGQAPSSTPGKRGS 92
ED + A+ T E G + ++ + P +A G PS +P+S+ +
Sbjct: 847 EDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKG 906
Query: 93 PQTPPGRS-PLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVD 151
++PP + S G G G++ R +E N ++ +
Sbjct: 907 FKSPPCEDFSVTGESEKRGEIIGK-------GLSGERAVEEEEEETANVEMSEKLCSQYG 959
Query: 152 TPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPP 211
TP G L PG P A AEE RC S+ + PP GPP
Sbjct: 960 TPVFSAPGHALHPGEP---ALGEAEE----RCLSPDDSTVKMAS---------PPPSGPP 1003
Query: 212 QSRGT----SPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPG 265
+ T SP++ S P+ ADSW PG G A E + G G
Sbjct: 1004 SATHTPFHQSPVEEKSEPQ-DFQEADSWGDTKRT--PGV--GKEDAAEETVKPGPEEG 1056
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 94.0 bits (232), Expect = 3e-18
Identities = 222/1002 (22%), Positives = 317/1002 (31%), Gaps = 198/1002 (19%)
Query: 2 PGERPRGAPPPTMTGDLQPRQVASSP------------GHPSQPPLEDN----------- 38
P E P PP P ++ +SP P PP E++
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512
Query: 39 TPATRTTKGAREAGGQAQAMELPEAQPRQA-------RDGELKPPSLRGQAPSSTPGKRG 91
+P + E + A+E P + P +A + L PP + P+S P +
Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP--EELPTSPPPEAS 570
Query: 92 SPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQL--PE 149
PP SP+ P + + R S P +E+P +P EA++L P
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP 630
Query: 150 VDTPQGPGTG-APLRPG--------LPR-TEAQPAAEELGFHRCFQEPPSSFT-STNYTS 198
D+P P +P+ P LP + P EE +E P+S + S
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLS 690
Query: 199 PSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSF----PGANFGVPPAE 254
P P +P PP+ SP S + P E G + P E
Sbjct: 691 PPPEDSPTSP-PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749
Query: 255 PEPIPKGSRPGGSPRG----VSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQ 310
P P+ P SP+ +S Q P L +P + A GP + QP+
Sbjct: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA-----EGPHLSP--QPE 802
Query: 311 GAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSD 370
P+P +P SP P + L+ S+ P +H +P
Sbjct: 803 ELHLSPQTEEPHLSPVPEEPCLSPQP----EESHLSPQSEEPCLSPRPEESHLSPE---- 854
Query: 371 SLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAP 430
L K PE+PP PGQ P P + L P
Sbjct: 855 -LEKPPLSPRPEKPPEE-------------------PGQC---------PAPEELPLFPP 885
Query: 431 GPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPT 490
P+ P L +P + PP PL + +G+PS +L P P P ++
Sbjct: 886 PGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITA 945
Query: 491 ARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP----------GPREKLPAVRSS 540
A +P + L L +P G +TP P P +
Sbjct: 946 A--APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003
Query: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNT 600
GSP A P+ PQ SP SL P + S LP
Sbjct: 1004 SPGSPV---------GPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPL----- 1049
Query: 601 AGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTH 660
S S LSP+ E S P P T SP PSP S P
Sbjct: 1050 --SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT-SPLPSPMGDLSCPA- 1105
Query: 661 YQPEPAKAF---------PFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPP 711
P PA A P DG+ A G+ P P + P L+G P P
Sbjct: 1106 --PSPAPALDDFSGLGEDTAPLDGIDAPGS------QPEPGQTPGSLASELKGSPVLLDP 1157
Query: 712 YPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPP 771
A + ++V C+Q S Q P P
Sbjct: 1158 E-------ELAPVTPMEVYPECKQTAGQGSPCE-------------------EQEEPRAP 1191
Query: 772 GLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASD 831
P+PP + +D + + + L GDA A L +P P
Sbjct: 1192 VAPTPPTL--IKSD-----IVNEISNLSQGDASASFPGS-------EPLLGSPDPEGGGS 1237
Query: 832 LDMEDDAKLDSLITEALNGMEYQSDN-PEIDSSFI----DVFADEEPSGPRGPSSGHPLK 886
L ME D + +D+ PE D S + + + G +G P +
Sbjct: 1238 LSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPAR 1297
Query: 887 SKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRS 928
S+ S + P + PR G G RGR + +S
Sbjct: 1298 SRIKQGRSS--------SFPGRRRPRGGAHGGRGRGRARLKS 1331
Score = 82.4 bits (202), Expect = 8e-15
Identities = 238/1027 (23%), Positives = 338/1027 (32%), Gaps = 135/1027 (13%)
Query: 77 SLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYI--------------- 121
++R A TP PG +P P L +G P ++
Sbjct: 357 TIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEA 416
Query: 122 --LGIASSRTKPTL-----DETPENPQLEAAQL---PEVDTPQGPGTGAPLRPGLPRTEA 171
LG A + +P L +E P P E + L PE P + L P A
Sbjct: 417 KPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA 476
Query: 172 QPAAEELGFHRCFQEPPSS---FTSTNYTSPSATP---------RPPAPGPPQSRGTSPL 219
P E L R +E P S S P ++P PP PP +PL
Sbjct: 477 SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL 536
Query: 220 QPGS-----YPEYQASGADSWPPAAE---NSFPGANFGVPPAEPEPI--PKGSRPGGSPR 269
P P ++ S PP E + P A+ PP E P+ P P P
Sbjct: 537 SPPPEASPLSPPFEESPLS--PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594
Query: 270 GVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQ 329
S FP + P P + + P P PE++ + P P
Sbjct: 595 EASRL--FPPFEESPLSPPPEE---SPLSPPPEASRLSPP----PEDSPMSPPPEESPMS 645
Query: 330 PAP-----SPLPCYQ-----GQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKI 379
P P SPLP + L+ + S P A+ +P P DS +
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP-EDSPTSPPPED 704
Query: 380 LPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQ 439
P PP + LP P R+ G SP P + L+ P PQ
Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ 764
Query: 440 LWDPTAAPYP------TPPGGPLAATRSMFFNGQPSPGQRLCLPQS-----APLPWPQVL 488
+P +P P P P + ++ + P P + PQ+ +P+P
Sbjct: 765 AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE--- 821
Query: 489 PTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP--GPREKLPAVRSSQGGSP- 545
P P P + + P P + L + P PR + P Q +P
Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPR---PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE 878
Query: 546 --ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP-PRVVGASPSESPLPSPATNTAG 602
LF G +P PL + +P +S G P L P P + SPS P SP
Sbjct: 879 ELPLFPPPG--EPSLSPL---LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD 933
Query: 603 STCSSLSPMSSSPANPS-SEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHY 661
LSP+ ++ A P+ S +L P G P + P PP + T
Sbjct: 934 PLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDP 993
Query: 662 QPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSS 721
+P P P P+ G A L E P P + + + L P+ PP +L
Sbjct: 994 EPVPPMILP-PSPGSPVGPASPILME-PLPPQCSPLLQHSL--VPQNSPPSQCSPPALPL 1049
Query: 722 ASLDQLDVL--LTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAA 779
+ L + + + + C L A G P+P A
Sbjct: 1050 SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPA 1109
Query: 780 PRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAK 839
P + D +GL A +G D P G P TP L AS+L
Sbjct: 1110 PAL--DDFSGLGEDT--------APLDGIDAP---GSQPEPGQTPGSL-ASEL-KGSPVL 1154
Query: 840 LDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKS----KAGVTPES 895
LD + ME + + EEP P P+ +KS + +
Sbjct: 1155 LDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQG 1214
Query: 896 KAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFR 955
A P + P +P P G + LG++ + A +G + L
Sbjct: 1215 DASASFPGSEPLLGSPD------PEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETD 1268
Query: 956 KDL--DSGGAAEG---SGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAP 1010
L D+G A G G G R+S R R G P R RRPR A G R
Sbjct: 1269 DSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGR-RRPRGGAHGGRGRGRA 1327
Query: 1011 RVPRAAA 1017
R+ A+
Sbjct: 1328 RLKSTAS 1334
Score = 72.8 bits (177), Expect = 6e-12
Identities = 198/795 (24%), Positives = 259/795 (32%), Gaps = 152/795 (19%)
Query: 1 MPGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMEL 60
+P + P G P L+PR + P +P P PA GA G Q E
Sbjct: 2171 VPSQDPFGLAPAY---PLEPRFPTAPPTYPPYPS-PTGAPAQPPMLGASSRPGAGQPGEF 2226
Query: 61 PEAQPRQAR------DGELKP--PSLRGQAPSSTPGKRGSPQTPPGRSP---------LQ 103
P R D LKP PSL A +PG G + P SP L+
Sbjct: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE 2286
Query: 104 APSRLAGRAEGS--PPQRYILGIASSRTK--------PTLDETPENPQLEAAQLPEVDTP 153
G + S PP + SS T P + + P P+ + P
Sbjct: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE------P 2340
Query: 154 QGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGP--- 210
Q PG G LRP P A F+ P S+T Y P TPRP P P
Sbjct: 2341 QSPGLG--LRPQEPPPAQALAPSPPSHPDIFR--PGSYTDP-YAQPPLTPRPQPPPPESC 2395
Query: 211 ----PQSRGTSPLQ--PGSYPEYQASGADSWPP---AAENSFPGA---------NFGVPP 252
P+S + P P S P+ Q+S P +AE P + PP
Sbjct: 2396 CALPPRSLPSDPFSRVPAS-PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPP 2454
Query: 253 AEPE------PIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADV-AGHA--------- 296
+ P+ P+ K RP P V+F+ A FPA + AG A
Sbjct: 2455 SRPQSRDPFAPLHKPPRP--QPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512
Query: 297 -----FTNGPLVFAF---HQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348
F P AF P +AVG P QP P P G+N H
Sbjct: 2513 GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP-------PHGINSH 2565
Query: 349 SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQD-GLGSTRGPPSSLPQRHFP 407
L P + + + + H S + + P + + GL R PPS LP
Sbjct: 2566 FGPGPTLGKPQSTNYTVA--TGNFHPSGSPLGPSSGSTGESYGLSPLR-PPSVLPPPAPD 2622
Query: 408 GQA-YRASGVDTSPG--PPDTELAAPGP------PPARLPQLWDPTAAPYPTPP---GGP 455
G Y + G G P + PG A LP DP +
Sbjct: 2623 GSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQ 2682
Query: 456 LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPT----ARPSPHGMEMLSRLPFPAGGP 511
R + Q ++A V P A PS E LSR P G
Sbjct: 2683 RQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGT 2742
Query: 512 EWQGGSQGALGT--AGKTPGP----------REKLPAVRSSQ--------GGSPALFTYN 551
+ + G + +G GP R PA SS GGS A Y
Sbjct: 2743 QDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAF--YQ 2800
Query: 552 GMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPM 611
PG+ PL Q T + + A +P P GS + +S
Sbjct: 2801 RAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTR 2860
Query: 612 SSSPANPSSEESQLPGPLGPSAFFHPPTHPQE----TGSPFPSPEPPHSLPTHY--QPEP 665
P P +PGP GP+ F + Q+ G+PFP PP P Y +P
Sbjct: 2861 LPGPGEP------VPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR-PRFYPVSEDP 2913
Query: 666 AKAFPFPADGLGAEG 680
+ P GL G
Sbjct: 2914 HRLAPEGLRGLAVSG 2928
Score = 67.4 bits (163), Expect = 3e-10
Identities = 206/922 (22%), Positives = 296/922 (32%), Gaps = 183/922 (19%)
Query: 420 PGPPDTELAAPGPPPARL-PQLWDPTAAPYPT---PPGGPLAATRSMFFNGQPSPGQRLC 475
PGP E G +L PQL P P P PL+ P RL
Sbjct: 409 PGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLS 468
Query: 476 LP--QSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTP-GPRE 532
P + P P+ L +RP +E P P P ++P P E
Sbjct: 469 PPPEELPASPLPEALHLSRP----LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE 524
Query: 533 KLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP--HGTPSLPPPRVVGASP-- 588
+ P SPAL T P A PL + +SP P+ PPP SP
Sbjct: 525 ESPP-------SPALETPLS-PPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576
Query: 589 SESPLPSPATNTAGSTCSSLS----PMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQET 644
ESP+ P + S S P SP +P EES L P S PP
Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS--- 633
Query: 645 GSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPF---PHEGP-----E 696
P PP P PE ++ P P + EE+P P E P E
Sbjct: 634 ----PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP----EESPLSPPPEESPTSPPPE 685
Query: 697 VGRGGL--QGFPRAPPPY-----PTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAH 749
R + P +PPP P SL S L++ +L + S L+
Sbjct: 686 ASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745
Query: 750 RQFCGLLLARAKDGH----QRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQA 805
R L R ++ H P P P VP + H QA
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS-------------PQA 792
Query: 806 EGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFI 865
EG P L+ P L S ++ L + E +P+ + S +
Sbjct: 793 EG----------PHLSPQPEELHLSP--QTEEPHLSPVPEEPCL-------SPQPEESHL 833
Query: 866 DVFADEEPSGPRGPSSGH--PLKSKAGVTPESKAPPPLPAATPDPQT----PRPGDRGC- 918
++E PR P H P K ++P + PP P P P+ P PG+
Sbjct: 834 SPQSEEPCLSPR-PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLS 892
Query: 919 PARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGL 978
P G P G P L ++L + E S S L
Sbjct: 893 PLLGEPALSEPGEPP-----------------LSPLPEELPLSPSGEPSLSPQLMPPDPL 935
Query: 979 RPRRNDGLGERPPPR--PRRPRTQAPGSRADPAPRVPRAAAL-------PEETRSSRRRR 1029
P + + PP P G++ D P P AA + P E +
Sbjct: 936 PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEP 995
Query: 1030 LPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQ----------PPPR 1079
+PP P + G L+ + Q + L ++ ++ Q P P
Sbjct: 996 VPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055
Query: 1080 GPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEA--------------------- 1118
P G+ E+ + + EP+ P +
Sbjct: 1056 SP--IGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALD 1113
Query: 1119 -----GGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKD 1173
G D AP + + GS+P PG++P + A+ +G P D +AP
Sbjct: 1114 DFSGLGEDTAPLDGIDAPGSQPEPGQTPGSL---------ASELKGSPVLLDPEELAPVT 1164
Query: 1174 PLQV-PTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASP 1232
P++V P +T+ + P +E +EP P + ++ + G+ AS
Sbjct: 1165 PMEVYPECKQTAGQGSPC----EEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASAS- 1219
Query: 1233 GLLIPEQPPPSRHDTGTPKPSG 1254
P S G+P P G
Sbjct: 1220 -------FPGSEPLLGSPDPEG 1234
Score = 62.4 bits (150), Expect = 9e-09
Identities = 130/552 (23%), Positives = 189/552 (34%), Gaps = 80/552 (14%)
Query: 205 PPAPG-----PPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGAN------FGVPPA 253
PP PG PP + T + + P ++ AD + S PG + +PP
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
Query: 254 EPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAW 313
P +P P G + FP + P+P+ A P++ A +P
Sbjct: 2167 VPAQVPSQD-PFGLAPAYPLEPRFPTAP-PTYPPYPSPTGAPA--QPPMLGASSRPGAGQ 2222
Query: 314 PEEAVGTGPAYPL--PTQPAPSPLP-CYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSD 370
P E T P P P+ P P P C + + G +S +P PF +
Sbjct: 2223 PGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLL--SPPPFGE 2280
Query: 371 S---LHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTEL 427
S L ++ P LG P S H G + V +P P
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGT---HLGGLELKTPDVFKAPLTPRASQ 2337
Query: 428 AAPGPPPARL-PQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQ 486
P P L PQ P A P+PP P + + P P+ P P P+
Sbjct: 2338 VEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPP---LTPRPQPPP-PE 2393
Query: 487 VLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPA 546
P + SR+P P+ Q SQ L TP P S++ P+
Sbjct: 2394 SCCALPPRSLPSDPFSRVP---ASPQSQSSSQSPL-----TPRPL-------SAEAFCPS 2438
Query: 547 LFTYNGMT-DPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTC 605
T + DP ++P ++PQ P PPR P + A + A ++
Sbjct: 2439 PVTPRFQSPDPYSRP----PSRPQSRDPFAPLHKPPR-----PQPPEVAFKAGSLAHTSL 2489
Query: 606 SSLSPMSSSPANPSSE-ESQLPGPLGPS--------AFFHPP-----THPQETGSPFPSP 651
+ ++ PA P+ E +++P P+ AF P T PQ G P P
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP 2549
Query: 652 E-------PPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHE---GPEVGRGG 701
PPH + +H+ P P P + A G F P G G
Sbjct: 2550 PVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP 2609
Query: 702 LQGFPRAPPPYP 713
L+ PPP P
Sbjct: 2610 LRPPSVLPPPAP 2621
Score = 61.6 bits (148), Expect = 1e-08
Identities = 157/627 (25%), Positives = 224/627 (35%), Gaps = 104/627 (16%)
Query: 1686 SRPPQDVCL-PEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQ 1744
S PP++ L P P + P S P+ + P +++ +S EDSL LP E+
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE 722
Query: 1745 RGGFLPEP------GTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGAS 1798
LP P ++ PH E SP P L+ Q + P L S
Sbjct: 723 -SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE-EPHLSPQAE-EPHL--------S 771
Query: 1799 PSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVS- 1857
P A HL P A EG +P +P+ E L PVP C+S
Sbjct: 772 PQPEEPCLCAVPEEPHLSPQA-----EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP 826
Query: 1858 ---NTHPSRRSQDPALSPPIRQLQL----------PGPGVAKSKDGILGLQELTPAAQSP 1904
+H S +S++P LSP + L P P + G E P P
Sbjct: 827 QPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886
Query: 1905 --PRVNPSGLEGGTVEGGKVACGPAQG----SPGG--------VQVTTLPAVAGHQLGLE 1950
P ++P E E G+ P SP G + LP +
Sbjct: 887 GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAA 946
Query: 1951 ADGHWGLLGQAEKTQG-QGTANQLQP------ENGVSPGGTDNHASVNASPKTALTGPTE 2003
A LG+ E G +G ++ P E +SP N P L P+
Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILP-PSP 1005
Query: 2004 GA-------VLLEKCKGSRAAMSLQEEAEPTPSPPSP-NRESLALALTAAHSRSGS---- 2051
G+ +L+E + + LQ P SPPS + +L L++ + S G
Sbjct: 1006 GSPVGPASPILMEPLP-PQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGV 1064
Query: 2052 ------EGRTPERASSPGLNKPLLATGDSPAPS-VGDLAACAPSPTSAAHMPCSLG---- 2100
E+ S P L + SP PS +GDL+ APSP A LG
Sbjct: 1065 SDEAELHEMETEKVSEPEC-PALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTA 1123
Query: 2101 PLPREDPLTS---PSRAQGGLGGQLPASPSCRDPPGPQQLLACSP--AWAPLEEADGVQA 2155
PL D S P + G L +L SP D P++L +P + ++ G +
Sbjct: 1124 PLDGIDAPGSQPEPGQTPGSLASELKGSPVLLD---PEELAPVTPMEVYPECKQTAGQGS 1180
Query: 2156 TTDTGAED-SPVAPPSLTTSPCDPKEALAGCLLQGEGS-------PL---EDPSSWPPGS 2204
+ E +PVAP T D ++ L QG+ S PL DP S
Sbjct: 1181 PCEEQEEPRAPVAPTPPTLIKSDIVNEISN-LSQGDASASFPGSEPLLGSPDPEGGGSLS 1239
Query: 2205 VSAVTCTHSGDTPKDSTLRIPEDSRKE 2231
+ T + +LR+ DS E
Sbjct: 1240 MELGVSTDVSPARDEGSLRLCTDSLPE 1266
Score = 59.7 bits (143), Expect = 6e-08
Identities = 148/654 (22%), Positives = 207/654 (31%), Gaps = 111/654 (16%)
Query: 895 SKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLF 954
S+ PP P TP T P +G+PK + + P Q + GK
Sbjct: 370 SRFSPPEPGDTP---TDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQL 426
Query: 955 RKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPR 1014
L++ E L P L P P P +A SR P P
Sbjct: 427 EPQLEAPLNEE---------MPLLPPPEESPLSPPPEESPTSPPPEA--SRLSPPPEELP 475
Query: 1015 AAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDE 1074
A+ LPE SR P P +E L + + + + S +E
Sbjct: 476 ASPLPEALHLSRPLEESPLSPP----------PEESPLSPPPESSPFSPLEESPLSPPEE 525
Query: 1075 QPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSR 1134
PP E L+ P P + + + P +P P SR
Sbjct: 526 SPP-------------SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP-PPEASR 571
Query: 1135 --PGPGRSPQARGPSRS-LETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSL 1191
P P SP + P S + A P + P P + + E S + P
Sbjct: 572 LSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE 631
Query: 1192 DFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPK 1251
D P + PE + S P E R P + P P PPP T +P
Sbjct: 632 DSPM-SPPPEESPMSPP-----PEVSRLSPLPVVSRLSPPPE-ESPLSPPPEESPT-SPP 683
Query: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPP-----------ARQPGEFL 1300
P S + P S +P P + +S ++ P R G L
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
Query: 1301 AP-VANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVP----VAKKGPQPYSSPH-SE 1354
+P P + P+ LS + P VP ++ + P+ SP E
Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803
Query: 1355 LFLGPKDLAGCFLEELH-----------PKPSARDAPPASSSCLCQDGEDAGSLEPQLPR 1403
L L P+ EE H P+P P S + L P+L +
Sbjct: 804 LHLSPQ------TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857
Query: 1404 SP----PGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADP 1459
P P EPG+ +P E LFP PP SLS
Sbjct: 858 PPLSPRPEKPPEEPGQCPAP---EELPLFP--------PPGEPSLS---------PLLGE 897
Query: 1460 PQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERT-VVPGAAP 1512
P + P +PP L E P+ PS P LS + PP + ++ AAP
Sbjct: 898 PALSEPGEPPLSP---LPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948
Score = 58.9 bits (141), Expect = 9e-08
Identities = 240/1033 (23%), Positives = 324/1033 (31%), Gaps = 224/1033 (21%)
Query: 1372 PKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDL 1431
P+P A +PP +++ G P +P G + + G P S PD
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGS---------PTTPAGLSTSADGFLKPPA---GSVPGPDS 2155
Query: 1432 PVDRFD--PPLYGSLSANRDSGLPFACA-----DPPQKTVPSD-PPYPSFLLLEEVSPML 1483
P + F PP + ++D PF A +P T P PPYPS PML
Sbjct: 2156 PGELFLKLPPQVPAQVPSQD---PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPML 2212
Query: 1484 ----------PSHFPDLSGGKVLSKTCPPERTVVPG-------AAPSLPGKGSGCSVALM 1526
P F G + P+ + P A P PG G G
Sbjct: 2213 GASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG------ 2266
Query: 1527 SHLSEDELEIQKLVTELESQLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQA 1586
+ + L E L+ K+ GA + S G LG P S
Sbjct: 2267 --KASEPLLSPPPFGESRKALEVKKEELGA-----SSPSYGPPNLGFVDSPSSGTHLGGL 2319
Query: 1587 TVPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPC 1646
+ D F A R + G Q P F PG
Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPG------- 2372
Query: 1647 AQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLD 1706
+ D + P +PR QP PP+ C P P
Sbjct: 2373 SYTDPYAQPPLTPRP-----QPP------------------PPESCCALPPRSLPS---- 2405
Query: 1707 AGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGAPAPE 1766
D P + ++ SS +S + R L E F P P T P +P P
Sbjct: 2406 ---------DPFSRVPASPQSQSSSQSPLTPRPLSAE---AFCPSPVT---PRFQSPDP- 2449
Query: 1767 AFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEG 1826
+ P P D PL P A +AG H + G GF
Sbjct: 2450 -YSRP-----PSRPQSRDPFAPLH-------KPPRPQPPEVAFKAGSLAHTSLGAGGFPA 2496
Query: 1827 NEFA-PAGASSLTAPRGREAWLVPVPSP-ACVSNTHPSRRS-----QDPALSPPIRQLQL 1879
A PAG P G+ V P A V P R + +P+L PP+ Q L
Sbjct: 2497 ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL 2556
Query: 1880 PGPGVAKSKDG---ILGLQELTPAAQSPPRVNPSGLEGGTVEGGK-VACGPAQGSPGGVQ 1935
P P S G LG + T + +PSG G G + G + P V
Sbjct: 2557 PPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL 2616
Query: 1936 VTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPK 1995
P + L A G+ EK + GT PG D P
Sbjct: 2617 PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQD--------PG 2668
Query: 1996 TALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRT 2055
+ TE LEK + + L + + +E+ A A A GS G
Sbjct: 2669 MSGLSQTE----LEKQRQRQRLRELLIRQQIQRNTLRQEKET-AAAAAGAVGPPGSWGAE 2723
Query: 2056 PERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGP--LPREDPLTSPSR 2113
P SSP + L+ G +P D ++ P S P LGP P +D L+ P
Sbjct: 2724 P---SSPAFEQ--LSRGQTPFAGTQDKSSLVGLPPSKLSGPI-LGPGSFPSDDRLSRPPP 2777
Query: 2114 AQGGLGGQLPASPSCRDPPGPQQLLACS---------PAWAPLEEA-----DGVQATTDT 2159
PA+PS D +QL+ S P PL++ QAT T
Sbjct: 2778 ---------PATPSSMD-VNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAAT 2827
Query: 2160 GAEDSPVAPPSLTTSPCDPKEALAGCL------LQGEGSPLEDPSSWPPGSVSAVTCTHS 2213
+ A T P ++AL L L G G P+ P+ G + H+
Sbjct: 2828 SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPA----GPAQFIELRHN 2883
Query: 2214 -------GDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTG 2266
G TP P+ R + E P R P G
Sbjct: 2884 VQKGLGPGGTPFPGQ-GPPQRPRFYPVSEDPHRL----------------------APEG 2920
Query: 2267 DEAQAGRGLPGPDPQSRGAP---------PHTNPDRMPRGHSSYS-PSNTARLGHREGQA 2316
A GLP P + AP PHT +P G + P ++ LG A
Sbjct: 2921 LRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLA 2980
Query: 2317 VTA--VPTEPPTL 2327
+ A +P E P L
Sbjct: 2981 LEAGKLPCEDPEL 2993
Score = 58.2 bits (139), Expect = 2e-07
Identities = 201/909 (22%), Positives = 288/909 (31%), Gaps = 150/909 (16%)
Query: 602 GSTCSSLSPMSSSP----ANPSSE-----ESQLPGPLGPSAFFHPPTHPQETGSPFPSPE 652
G +S+ P P A P + E QL PL PP P+E+ P
Sbjct: 398 GGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPP--PEES----PLSP 451
Query: 653 PPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCL------EETPFPHEGPEVGRGGLQGFP 706
PP PT PE ++ P P + L A + L EE+P E P
Sbjct: 452 PPEESPTSPPPEASRLSP-PPEELPASPLPEALHLSRPLEESPLSPPPEES--------P 502
Query: 707 RAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQR 766
+PPP + L + L + + S L+ +
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP--------LSPPFEESPL 554
Query: 767 SPGPPGLPS--PPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP 824
SP P LP+ PP A R+ +S ++ P + P +P
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPE-------ESPMSPPPEASRLFPPFEESP 607
Query: 825 FPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEP-SGPRGPSSGH 883
P + + + L +P + S + +E P S P S
Sbjct: 608 LSPPPEESPLSPPPEASRL-------------SPPPEDSPMSPPPEESPMSPPPEVSRLS 654
Query: 884 PLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGR 943
PL + ++P + P P P +P P +R P +P D+P+
Sbjct: 655 PLPVVSRLSPPPEESPLSPPPEESPTSPPPE----ASRLSPPPEDSPTSPPPEDSPASPP 710
Query: 944 QQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRT--QA 1001
+ L L L E L PR + PRP P QA
Sbjct: 711 PEDSLMSLPLEESPLLP--LPEEPQLCPRSEGPHLSPRPEE---PHLSPRPEEPHLSPQA 765
Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061
P P P A+PEE S + P P+ + +E L V ++ L
Sbjct: 766 EEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824
Query: 1062 REYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGD 1121
S + P P E EL + P P+KP + Q
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPE------ESHLSPELEKPPLSPRPEKPPEEPGQ----- 873
Query: 1122 GAPANPEEPGGSRPG-PGRSPQARGPSRSL----------ETGAAAREGGPKCADRPSVA 1170
PA E P PG P SP P+ S E + G P + P +
Sbjct: 874 -CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLS--PQLM 930
Query: 1171 PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAE-ESAPDSTEFTEALRSPPAACAGEMG 1229
P DPL P + + P+L E + P A+ +S P+S
Sbjct: 931 PPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPL----------------- 973
Query: 1230 ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSK 1289
A+P L P PPP + T P+P P P+P G P G +P+
Sbjct: 974 AAPILETPISPPPEANCT-DPEP------VPPMILPPSP------GSPVGPASPILMEPL 1020
Query: 1290 DPPARQP--GEFLAPVANPSSTACPK--PSVLSSKISSFG-----CDPAGFNRDPLGVPV 1340
PP P L P +P S P P + S +S G D A +
Sbjct: 1021 -PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS 1079
Query: 1341 AKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQ 1400
+ P S S L P + P P+ D DG DA +P+
Sbjct: 1080 EPECPALEPSATSPL---PSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPE 1136
Query: 1401 LPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPP 1460
P PG+ +E SP L+ L P P++ +Y G P + P
Sbjct: 1137 -PGQTPGSLASE--LKGSPVLLDPEELAPVTPME-----VYPECKQTAGQGSPCEEQEEP 1188
Query: 1461 QKTVPSDPP 1469
+ V PP
Sbjct: 1189 RAPVAPTPP 1197
Score = 57.8 bits (138), Expect = 2e-07
Identities = 118/509 (23%), Positives = 167/509 (32%), Gaps = 68/509 (13%)
Query: 2026 PTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAAC 2085
P SP SP E+ L S E + L++PL + SP P L+
Sbjct: 453 PEESPTSPPPEASRL------SPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS-- 504
Query: 2086 APSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASP----SCRDPPGPQQLLACS 2141
P P S+ P E PL+ P + + P SP S PP + L+
Sbjct: 505 -PPPESSPFSPLE------ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPP 557
Query: 2142 PAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWP 2201
P P + E+SP++PP SP P + E SPL P
Sbjct: 558 PEELPTSPPPEASRLSPP-PEESPMSPPP-EESPMSPPPEASRLFPPFEESPLSPPPEES 615
Query: 2202 PGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP--SVAVRATG 2259
P S + P+DS + P + R + P+ +SP + +
Sbjct: 616 PLSPPP-EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Query: 2260 LSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYS-----------PSNTAR 2308
+PT +A R P P+ PP +P P S S P
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
Query: 2309 LGHREGQAVTAVPTEPPTLQGAGPDSP-ACLEGEMGTSSKEPEDP---GTPETGR-SGAT 2363
EG ++ P EP P+ P + E S +PE+P PE S
Sbjct: 735 CPRSEGPHLSPRPEEPHL--SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA 792
Query: 2364 KMPRVTCPSTGLGLGRTT-------APSSTASDFQSD----SPQSHRNASHQTPQGDPLG 2412
+ P ++ L L T P Q + SPQS P+ L
Sbjct: 793 EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLS 852
Query: 2413 PQDLKQRSRGYKKKPASTENGQWKG--QAPHGPVTCEVCAASFRSGPGLSRHKARKHRPH 2470
P+ K +KP E GQ + P P E + P LS
Sbjct: 853 PELEKPPLSPRPEKPPE-EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE--------- 902
Query: 2471 PGAPAEPSPAALPAQQPLEPLAQKCQPPR 2499
P EP + LP + PL P + P+
Sbjct: 903 ---PGEPPLSPLPEELPLSPSGEPSLSPQ 928
Score = 50.4 bits (119), Expect = 3e-05
Identities = 137/577 (23%), Positives = 181/577 (31%), Gaps = 119/577 (20%)
Query: 1107 PQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR---GPSRSLETGAAAREGGPKC 1163
PQ P + Q+ G APA P EP P P P++ GA++R G +
Sbjct: 2165 PQVPAQVPSQDPFGL-APAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
Query: 1164 ADRPSVAPKDPLQVPTNTETSEETR-PSLDFPQEAKEPETAEESAPDSTEFTEALRSPPA 1222
+ + P P P+ + + R PSLD + P A +E L SPP
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKA------SEPLLSPPP 2277
Query: 1223 ACAG---------EMGAS------PGLLIPEQPPPSRHDTGTP--KPSGSLANTAPHGSS 1265
E+GAS P L + P H G P A P S
Sbjct: 2278 FGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQ 2337
Query: 1266 ---PTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKIS 1322
+PG+G P QA P +PG + P A P T P+P S
Sbjct: 2338 VEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP---PPPES 2394
Query: 1323 SFGCDPAGFNRDPLG-VPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHP--------- 1372
P DP VP + PQ SS S L P + P
Sbjct: 2395 CCALPPRSLPSDPFSRVPAS---PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451
Query: 1373 ----KPSARD------APPA--------SSSCLCQDGEDAGSLEPQLPRSP--------- 1405
+P +RD PP + L AG LP P
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
Query: 1406 ----------PGT----AETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSG 1451
PGT P R P + SL P +P PP ++++ G
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPP--HGINSHFGPG 2569
Query: 1452 LPFACADPPQKTVPSDPPYPSFLLLEE----------VSPM-----LPSHFPDLSGGKVL 1496
TV + +PS L +SP+ LP PD S +
Sbjct: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLS 2629
Query: 1497 SKTCPPERTVVPGAAPSLPGKGSGCSVAL----------MSHLSEDELEIQKLVTELESQ 1546
P PG G G S+A MS LS+ ELE Q+ L
Sbjct: 2630 HGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLREL 2689
Query: 1547 LQRSKDTRGAPRELAEAESVGRVELGT----GTEPPS 1579
L R + R R+ E + +G G EP S
Sbjct: 2690 LIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSS 2726
Score = 49.7 bits (117), Expect = 6e-05
Identities = 143/595 (24%), Positives = 191/595 (32%), Gaps = 154/595 (25%)
Query: 768 PGPPGLPSPPAAPRV---PADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATP 824
PG G P P AAP + AGL + A FL G D P FL P
Sbjct: 2110 PGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGEL-FLKLPPQVP 2168
Query: 825 FPLPASD-LDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGH 883
+P+ D + L EP P P +
Sbjct: 2169 AQVPSQDPFGLAPAYPL-------------------------------EPRFPTAPPTYP 2197
Query: 884 PLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARG-------------RPKTRSL- 929
P S G + A PP+ A+ P +PG+ G +P+ SL
Sbjct: 2198 PYPSPTG----APAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLD 2253
Query: 930 GLAPTEADAPSQGRQQR----------RGKQLKLFRKDLDSGGAAEG-----------SG 968
LA E+ G+ K L++ +++L + + G SG
Sbjct: 2254 NLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSG 2313
Query: 969 SGGGG---------------RASGLRPRRNDGLGERP----------PPRPRRPRTQAPG 1003
+ GG RAS + P+ + GLG RP P P P PG
Sbjct: 2314 THLGGLELKTPDVFKAPLTPRASQVEPQ-SPGLGLRPQEPPPAQALAPSPPSHPDIFRPG 2372
Query: 1004 SRADP---APRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNR 1060
S DP P PR P E+ + LPPR P +R A + Q +
Sbjct: 2373 SYTDPYAQPPLTPRPQPPPPESCCA----LPPRSLPSDPFSRVPASPQ-------SQSSS 2421
Query: 1061 LREYDFASESEEDEQPPPRGPGFRG--RRGRGEKRKE-----VELTQGPREDEPQKPRKA 1113
S E P P P F+ R R + L + PR P+ KA
Sbjct: 2422 QSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKA 2481
Query: 1114 ---ARQEAGGDGAPA----------NPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGG 1160
A G G PA + + P G P RSP G + T + R
Sbjct: 2482 GSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP---GTGAFVGTPSPMRFTF 2538
Query: 1161 PKCADRPSVAPKDP---LQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEAL 1217
P+ PS+ P P L P + P+L PQ P
Sbjct: 2539 PQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSG------- 2591
Query: 1218 RSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272
SP +G G S G L P +PP P P GSL + HG+S G+ S
Sbjct: 2592 -SPLGPSSGSTGESYG-LSPLRPPSV---LPPPAPDGSLPYLS-HGASQRSGITS 2640
Score = 48.5 bits (114), Expect = 1e-04
Identities = 170/678 (25%), Positives = 228/678 (33%), Gaps = 154/678 (22%)
Query: 21 RQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKP----P 76
R+V ++ P +DN A R K ++A Q +Q + G++ P
Sbjct: 2050 RKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQIN---------KQTKVGDIARKTDRP 2100
Query: 77 SLRGQAPSSTPGKRGSPQTPPGRSPL------QAPSRLAGRAEG--SPPQRYILGIASSR 128
+L + P PG GSP PP +P P+ L+ A+G PP + G S
Sbjct: 2101 ALHLRIPPQ-PGALGSP--PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG-PDSP 2156
Query: 129 TKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPP 188
+ L P+ P AQ+P D P G PL P P PP
Sbjct: 2157 GELFLKLPPQVP----AQVPSQD-PFGLAPAYPLEPRFPTA-----------------PP 2194
Query: 189 SSFTSTNYTSPSATP-RPPAPGPPQSRGTSPLQPGSY-------PEYQASGADSWP---- 236
T Y SP+ P +PP G G QPG + P +Q S D +
Sbjct: 2195 ---TYPPYPSPTGAPAQPPMLGASSRPGAG--QPGEFHTTPPGTPRHQPSTPDPFLKPRC 2249
Query: 237 PAAEN----SFPGANFGV---PPAEPEPIPKG-------------SRPGGSPRGVSF-QF 275
P+ +N PG G P P P + S P P + F
Sbjct: 2250 PSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDS 2309
Query: 276 PFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQP-APSP 334
P H + DV PL Q + P +G P P P Q APSP
Sbjct: 2310 PSSGTHLGGLELKTPDVF-----KAPLTPRASQVEPQSP--GLGLRPQEPPPAQALAPSP 2362
Query: 335 LPCYQGQPGGLNRHSDL--SGALSSPGAAHS-APRPFSDSLHKSLTKILPERPPSAQDGL 391
H D+ G+ + P A PRP +S + P PS D
Sbjct: 2363 -----------PSHPDIFRPGSYTDPYAQPPLTPRP-QPPPPESCCALPPRSLPS--DPF 2408
Query: 392 GSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP---PPARLPQLWDPTAA-- 446
P S P S P P +P P PP+R PQ DP A
Sbjct: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR-PQSRDPFAPLH 2467
Query: 447 --PYPTPP-----GGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARP-----S 494
P P PP G LA T S+ G P+ LP +P+ +P S
Sbjct: 2468 KPPRPQPPEVAFKAGSLAHT-SLGAGGFPA-----ALPAGPAGELHAKVPSGQPPNFVRS 2521
Query: 495 PHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLP---AVRSSQGGSPALFTYN 551
P G P P Q + +L K P P+ LP + S G P L
Sbjct: 2522 P-GTGAFVGTPSPMRFTFPQAVGEPSL----KPPVPQPGLPPPHGINSHFGPGPTLGK-- 2574
Query: 552 GMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPM 611
Q + VA P G+P P G S SPL P+ + SL +
Sbjct: 2575 ------PQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYL 2628
Query: 612 SSSPANPSSEESQLPGPL 629
S + +S+ S + P+
Sbjct: 2629 S----HGASQRSGITSPV 2642
Score = 47.4 bits (111), Expect = 3e-04
Identities = 225/941 (23%), Positives = 290/941 (30%), Gaps = 209/941 (22%)
Query: 1688 PPQDVCLPEPSKQPGPQLDAGSLA-----KCSPDQELSFPKNKEAASSQESEDSLRLLPC 1742
PPQ L P P + GS S D L P E L+L P
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP- 2165
Query: 1743 EQRGGFLPEPGTADQPHRGAPAPEAFG-SPAVHLAPDLAFQGDGAPPLDATWPFGASPSH 1801
Q P+ + FG +PA L P APP T+P SP+
Sbjct: 2166 --------------QVPAQVPSQDPFGLAPAYPLEPRFPT----APP---TYPPYPSPTG 2204
Query: 1802 AAQGHSAGRAGGHLHPTAGRPGFEGNEF--APAGASSLTAPRGREAWLVPVPSPACVSNT 1859
A G P AG+PG EF P G PR + + P P C S
Sbjct: 2205 APA--QPPMLGASSRPGAGQPG----EFHTTPPGT-----PRHQPSTPDPFLKPRCPSLD 2253
Query: 1860 HPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPS--GLEGGTV 1917
+ L+ P + PG G K+ + +L SPP S LE
Sbjct: 2254 N---------LAVP----ESPGVGGGKASEPLL----------SPPPFGESRKALEVKKE 2290
Query: 1918 EGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPEN 1977
E G A P+ G P + P+ H GLE K A+Q++P+
Sbjct: 2291 ELG--ASSPSYGPPN-LGFVDSPSSGTHLGGLELK-----TPDVFKAPLTPRASQVEPQ- 2341
Query: 1978 GVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRES 2037
SPG + A + P+ + GS Q P P PP P
Sbjct: 2342 --SPGLGLRPQEPPPAQALAPSPPSHPDIFRP---GSYTDPYAQPPLTPRPQPPPPES-- 2394
Query: 2038 LALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPC 2097
AL S R P S ++ L +P P + A PSP + P
Sbjct: 2395 -CCALPPRSLPSDPFSRVPASPQSQSSSQSPL----TPRPLSAE--AFCPSPVT----PR 2443
Query: 2098 SLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEA--DGVQA 2155
P DP + P P+ P RDP P L P P E A G A
Sbjct: 2444 FQSP----DPYSRP-----------PSRPQSRDPFAP---LHKPPRPQPPEVAFKAGSLA 2485
Query: 2156 TTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGD 2215
T GA P A P+ K PS PP V +
Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKV----------------PSGQPPNFVRSPGTGAFVG 2529
Query: 2216 TPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGL 2275
TP SP R T P G S V GL P G + G G
Sbjct: 2530 TP------------------SPMRFTFPQAVGEPSLKPPVPQPGLPP-PHGINSHFGPGP 2570
Query: 2276 PGPDPQSRG---APPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTL----- 2327
PQS A + +P P G SS S + L +V P +L
Sbjct: 2571 TLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSH 2630
Query: 2328 ---QGAGPDSPACLEGE----MGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRT 2380
Q +G SP + MG+S E PGT + G SG ++
Sbjct: 2631 GASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELL 2690
Query: 2381 TAPSSTASDFQSDSPQSHRNASHQTPQG----DPLGPQDLKQRSRGYKKKPASTENGQWK 2436
+ + + + A P G +P P +Q SRG + +
Sbjct: 2691 IRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPA-FEQLSRGQTPFAGTQDKSSLV 2749
Query: 2437 GQAPH---GPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPS--------------- 2478
G P GP+ GPG R RP P PA PS
Sbjct: 2750 GLPPSKLSGPIL----------GPGSFPSDDRLSRPPP--PATPSSMDVNSRQLVGGSQA 2797
Query: 2479 -------PAALPAQQPLEPLAQKCQPPRKKSHRVSGKER-PNHSRGDPSHVTQPPPAQGS 2530
P +LP QQ + L Q+ Q S R + R P+ + P G
Sbjct: 2798 FYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGI 2857
Query: 2531 KEVLRAPGSPHSQQLHPPSPTEHEVDVKT---PASKPRPDQ 2568
L PG P P E +V+ P P P Q
Sbjct: 2858 STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQ 2898
Score = 47.0 bits (110), Expect = 4e-04
Identities = 116/500 (23%), Positives = 176/500 (35%), Gaps = 100/500 (20%)
Query: 845 TEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPP---L 901
T L G E + +P + S A E PS G PL G TPES A P
Sbjct: 4018 TLLLTGKEQNTVDPAVSSE-----ATEGPS----THQGGPLA--IGTTPESMATEPGEVK 4066
Query: 902 PAATPDPQT----PRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKD 957
P+ + D Q P+P +P+ SL L P G+QQ++ L
Sbjct: 4067 PSLSGDSQLLLVQPQP---------QPQPSSLQLQPP---LRLPGQQQQQVSLLHT---- 4110
Query: 958 LDSGGAAEGS-GSGGGGRASG---LRPRRNDGLGERPPPR------PRRPRTQAPGSRAD 1007
+GG + G GSG AS L + + LG++P P++P + P + +
Sbjct: 4111 --AGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERP-MQNN 4167
Query: 1008 PAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGG-AWGKELILKIVQQKNRLREYDF 1066
P+ P+ + + + + P + + +G A +L QQ+ +L+
Sbjct: 4168 TGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227
Query: 1067 ASESEEDEQ----PPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDG 1122
+ ++ + PP + PG + QG +PQ G G
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPG-----------TQTSPLQGLLGCQPQL--------GGFPG 4268
Query: 1123 APANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTE 1182
P + G+ P P P+ P +L TG P PK P Q+P+
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--- 4325
Query: 1183 TSEETRPSLDFPQEAKEPET---AEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQ 1239
PS P EA+ P T + + E SP AA + S GL
Sbjct: 4326 ------PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGL----- 4374
Query: 1240 PPPSRHDTGTPKPSGSLANT-APHGSSPTPGVGSLLGG---PGGTQAPVSHNSKDPPARQ 1295
G P +LA T P SS PG + G P +Q + ++ P
Sbjct: 4375 --------GPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCAL 4426
Query: 1296 PGEFLAPVANPSSTACPKPS 1315
+ + AN P S
Sbjct: 4427 GAQSVKREANGEPIGAPGTS 4446
Score = 45.8 bits (107), Expect = 8e-04
Identities = 104/412 (25%), Positives = 148/412 (35%), Gaps = 52/412 (12%)
Query: 327 PTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPS 386
P Q + G P +H GAL G +++ +++ E P +
Sbjct: 3987 PQQQQQQQVALGPGMPAKPLQHFSSPGAL---GPTLLLTGKEQNTVDPAVSSEATEGPST 4043
Query: 387 AQDG---LGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDP 443
Q G +G+T ++ P P + + + P P + PP RLP
Sbjct: 4044 HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQ 4103
Query: 444 TAAPYPTPPGGP-----------------LAATRSMFFNGQP-SPGQRLCLPQSAPLPWP 485
+ T GG L A S+ QP S Q L PQ L P
Sbjct: 4104 QVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERP 4163
Query: 486 QVLPTA-RPSPHGMEMLSRLPFPAGG-----PEWQGGSQGALGTAGK----TPGPREKLP 535
T +P G + S P G + + QG L + +P +++L
Sbjct: 4164 MQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223
Query: 536 AVRSSQG--GSPALFTYNGMTDPGAQ--PL--FFGVAQPQVSPHGTPSLPPPRVVGASPS 589
A+ + S A+ +PG Q PL G QPQ+ P P + +GA P
Sbjct: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLG-CQPQLGGFPGPQTGPLQELGAGPR 4282
Query: 590 -ESPLPSPATNTAGSTCSSLSPMSSSPANPSSEE----SQLPGPLG--PSAFFHPPTHPQ 642
+ P PA A ST L P+ +P S +E SQLP P P+ PPTHP
Sbjct: 4283 PQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPG 4342
Query: 643 ETGSPFPSPEPPHSLPTHYQPEPAK-AFPFPADGLGAEGAFQCLEETPFPHE 693
P+ EPP P P A+ A + GLG L ET P +
Sbjct: 4343 TPKPQGPTLEPP---PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQ 4391
Score = 44.3 bits (103), Expect = 0.002
Identities = 107/448 (23%), Positives = 141/448 (31%), Gaps = 60/448 (13%)
Query: 2471 PGAPAEPSPAALPAQQPLEP-LAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQG 2529
P +P E SP + P + P P L PP + S E S T PPP
Sbjct: 511 PFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP--- 567
Query: 2530 SKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKR-----EG 2584
E R P + PP P E + AS+ P E L P E E
Sbjct: 568 --EASRLSPPPEESPMSPP-PEESPMSPPPEASRLFPP-FEESPLSPPPEESPLSPPPEA 623
Query: 2585 RRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYA 2644
R P DSP + + RL S LPV + + S SP
Sbjct: 624 SRLSPPPE-DSPMSPPPEESPMSPPPEVSRL---SPLPVVSRLSPPPEESPLSPPPEESP 679
Query: 2645 ASPSHCLSVEGGPEADG--EQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRML 2702
SP S P D PP + P E +L E+ P + L
Sbjct: 680 TSPPPEASRLSPPPEDSPTSPPPEDSPASP-----PPEDSLMSLPLEESPLLPLPEEPQL 734
Query: 2703 CPGRMDGAALGEQPT-------------GQKGASARGFWGPRETKALGVCKESGSEPAED 2749
CP R +G L +P + P E V +E P +
Sbjct: 735 CP-RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAE 793
Query: 2750 SSRAHSRSEEGVWEENT--PPLGPLGF-PETSSSPADSTTSS-----CLQGLPD----NP 2797
+ EE T P L P+ P S P +S S CL P+ +P
Sbjct: 794 GPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSP 853
Query: 2798 DTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGR--LTRKRNPHVYGKRCE 2855
+ + P P P L LFPP G L+ + E
Sbjct: 854 ELEKPPLSPRPEKPPEEPGQCPAPEEL--------PLFPPPGEPSLSPLLGEPALSEPGE 905
Query: 2856 KPVLPLPTQPSFEEGGDPTLGPARLPTD 2883
P+ PLP + G+P+L P +P D
Sbjct: 906 PPLSPLPEELPLSPSGEPSLSPQLMPPD 933
Score = 43.9 bits (102), Expect = 0.003
Identities = 74/305 (24%), Positives = 110/305 (36%), Gaps = 39/305 (12%)
Query: 3636 TFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSL---APGELARGTENGMK 3692
T GS T PAG +S+ P+ ++ P P + L P ++ G+
Sbjct: 2123 TIFIGSPTTPAGLSTSAD--GFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLA 2180
Query: 3693 PATPKAKPGPSSQGSGSPRPGTKTGGGSQP-------QPASGQLQSETATTPAKPSFPSR 3745
PA P P++ + P P + TG +QP +P +GQ T P P
Sbjct: 2181 PAYPLEPRFPTAPPTYPPYP-SPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPS 2239
Query: 3746 SPAPERLPARAQAKSCT--KGPREAGEQGPHGSLGPKEKGES----STKRKKGQVPGPAR 3799
+P P P + + P G + L P GES K+++ P+
Sbjct: 2240 TPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSY 2299
Query: 3800 SESVGSFGRAPSA-----------PD--KPPRTPR----KQATPSRVLPTKPKPNSQNKP 3842
F +PS+ PD K P TPR + +P L + P +Q
Sbjct: 2300 GPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALA 2359
Query: 3843 RPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAE-PAEPHTHRTAEAQS 3901
PPS PG D + RP PP+ A+ P++P + A QS
Sbjct: 2360 PSPPSHPDIFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQS 2417
Query: 3902 DLLSQ 3906
SQ
Sbjct: 2418 QSSSQ 2422
Score = 43.9 bits (102), Expect = 0.003
Identities = 66/253 (26%), Positives = 94/253 (37%), Gaps = 31/253 (12%)
Query: 3547 LERPENEAS---PGSPGPLLQ--QALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGA 3601
LERP + P PGP+LQ Q LP +P G +G A + P
Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA--------KNPQL 4211
Query: 3602 RGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPA----GCQSSSKDRSA 3657
R +P Q+ L ++++ S V + P G+ T P GCQ
Sbjct: 4212 R-HLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQ--EPGTQTSPLQGLLGCQPQLGGFPG 4268
Query: 3658 AST-PSKALKFPVHPRKAVGSLAP-GELARGTENG-MKPATPKAKPGPSSQGSGSPRPGT 3714
T P + L P+ AP G L+ G G + P P + P + S P P +
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 3715 KTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPH 3774
+ P QL TP KP P+ P P R+ A + T + G P
Sbjct: 4329 QL-------PTEAQLPPTHPGTP-KPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
Query: 3775 GSLGPKEKGESST 3787
+L +K E S+
Sbjct: 4381 DNLAETQKPEQSS 4393
Score = 42.7 bits (99), Expect = 0.007
Identities = 71/265 (26%), Positives = 93/265 (35%), Gaps = 31/265 (11%)
Query: 1217 LRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTP------KPSGSLANTAPHGSSPTPGV 1270
L+ PP A P L P P R T P P+G+ A G+S PG
Sbjct: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA 2220
Query: 1271 GSLLGGPGGTQAPVSHNSKDPPARQPGEFLAP-VANPSSTACPK-PSVLSSKISSFGCDP 1328
G PG + P+ P FL P + + A P+ P V K S P
Sbjct: 2221 GQ----PGEFHTTPPGTPRHQPST-PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSP 2275
Query: 1329 AGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDL--AGCFLEELHPK-PSARDAPPASSS 1385
F + V K+ S + LG D +G L L K P AP +
Sbjct: 2276 PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335
Query: 1386 CLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDL--PVDRFDPPLYGS 1443
+ L PQ P PP A A SPP+ PD+ P DP
Sbjct: 2336 SQVEPQSPGLGLRPQEP--PPAQA-----LAPSPPS------HPDIFRPGSYTDPYAQPP 2382
Query: 1444 LSANRDSGLPFACADPPQKTVPSDP 1468
L+ P +C P +++PSDP
Sbjct: 2383 LTPRPQPPPPESCCALPPRSLPSDP 2407
Score = 42.4 bits (98), Expect = 0.009
Identities = 116/486 (23%), Positives = 148/486 (30%), Gaps = 78/486 (16%)
Query: 3455 APGPGED--RPPPRGS--SPILSE---GSLPALLHLCSEVAPSTTKGWPETLERPVDPVT 3507
+P P E PPP S SP E LP LHL + S PE P +
Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509
Query: 3508 HPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSP----GPLL 3563
P P PP SP AL P EASP SP PL
Sbjct: 510 SPFS----PLEESPLSPPEESPPSPALETPLS----------PPPEASPLSPPFEESPLS 555
Query: 3564 QQALPLGASLPRPGAR--GQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHL------ 3615
L S P +R E +P P R P F+E L
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP-FEESPLSPPPEE 614
Query: 3616 --LQKEKEVSSSHMVSEGGPRGTFHKGSATKP------------AGCQSSSKDRSAASTP 3661
L E S E P + S P S + S S P
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Query: 3662 SKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQ 3721
+ + P P L+P + P A P P P +
Sbjct: 675 PE--ESPTSPPPEASRLSPPP--EDSPTSPPPEDSPASPPPEDSLMSLPLEESPL----L 726
Query: 3722 PQPASGQL--QSETATTPAKPSFPSRSPAPER--LPARAQAKSCTKGPRE----AGEQGP 3773
P P QL +SE +P P SP PE L +A+ + P E A + P
Sbjct: 727 PLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786
Query: 3774 HGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPT- 3832
H L P+ +G + + + P E P P P+ +P P
Sbjct: 787 H--LSPQAEGPHLSPQPEELHLSPQTEEP--HLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
Query: 3833 KPKPNS-------QNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHG 3885
P+P + P P E+ EPG + L P G P L P A+
Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL-- 900
Query: 3886 AEPAEP 3891
+EP EP
Sbjct: 901 SEPGEP 906
Score = 42.4 bits (98), Expect = 0.009
Identities = 60/214 (28%), Positives = 78/214 (36%), Gaps = 28/214 (13%)
Query: 3693 PATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSET--ATTPAKPSFPSRSP-AP 3749
PA+P+++ SSQ +PRP + P P + + QS + P++P SR P AP
Sbjct: 2412 PASPQSQS--SSQSPLTPRP--LSAEAFCPSPVTPRFQSPDPYSRPPSRPQ--SRDPFAP 2465
Query: 3750 ERLPARAQA-----KSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVG 3804
P R Q K+ + G G +L GE K GQ P RS G
Sbjct: 2466 LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTG 2525
Query: 3805 SFGRAPSA-----PDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQR 3859
+F PS P K P LP NS P P +P T
Sbjct: 2526 AFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGP-----TLGKPQSTNY 2580
Query: 3860 KDRLGKAFPQGRPLLRPPKRGTA--VHGAEPAEP 3891
G P G PL P G+ +G P P
Sbjct: 2581 TVATGNFHPSGSPL--GPSSGSTGESYGLSPLRP 2612
Score = 40.8 bits (94), Expect = 0.027
Identities = 163/808 (20%), Positives = 279/808 (34%), Gaps = 185/808 (22%)
Query: 1055 VQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQK----- 1109
+QQ+ +L++ + ++ + + + ++ + +++++ + Q ++ + Q+
Sbjct: 3920 LQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLN 3979
Query: 1110 -------PRKAARQEAG-GDGAPANP----EEPGGSRPG---PGRSPQARGPSRSLET-- 1152
P++ +Q+ G G PA P PG P G+ P+ S E
Sbjct: 3980 QSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
Query: 1153 GAAAREGGPKCAD-------------RPSVAPKDPLQV----PTNTETSEETRPSLDFPQ 1195
G + +GGP +PS++ L + P +S + +P L P
Sbjct: 4040 GPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPG 4099
Query: 1196 EAKEP-------------ETAEESAPDSTEFTEALRSPPAACAGEMGA-SPGLLIPEQPP 1241
+ ++ + S+ +++ L P + + G+ + LL P+QP
Sbjct: 4100 QQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPM 4159
Query: 1242 ---PSRHDTGT--PKPSGSL-ANTAPHGSSPTPGVGSLLGGPGGTQA--PVSHNSKDPPA 1293
P +++TG PKP L + G P VG L G A P +
Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219
Query: 1294 RQPGEFLAPVANPSSTAC------PKPSVLSSKISSF-GCDP--AGFNR------DPLGV 1338
+Q L S A +P +S + GC P GF LG
Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGA 4279
Query: 1339 PVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKP--SARDAP------PASSSCLCQD 1390
+GP +P L GP L +HP P S+ P P+ SS L +
Sbjct: 4280 GPRPQGPPRLPAPPGALSTGP------VLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTE 4333
Query: 1391 GE----DAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSA 1446
+ G+ +PQ P P P A TL S L P
Sbjct: 4334 AQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGP----------------- 4376
Query: 1447 NRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPMLPSHFPDLSG------GKVLSKTC 1500
DPP + P E S ++P H ++G ++ K
Sbjct: 4377 ----------WDPPDNLAETQKP--------EQSSLVPGHLDQVNGQVVPEASQLSIKQE 4418
Query: 1501 PPERTVVPGA--------APSLPGKGSGCSVALMSHLSE-DELEIQKLVTELESQLQRSK 1551
P E GA + G+ + L SE L +QKL+ QL +
Sbjct: 4419 PREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGR 4478
Query: 1552 DTRGAPREL---AEAESVGRVELGTGTEPPSQRRTCQATVP----HEDTFSAAD-LTRVG 1603
+ G E+ +++ G + GT PS + A P + A+D L
Sbjct: 4479 GSEGLRAEINGHIDSKLAGLEQKLQGT--PSNKEDAAARKPLTPKPKRVQKASDRLVSSR 4536
Query: 1604 ESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSG----APFS- 1658
+ +G ++ A ++ ++ +LLP + + + APF
Sbjct: 4537 KKLRKEDGVRASEALLKQLK---------------QELSLLPLTEPAITANFSLFAPFGS 4581
Query: 1659 --PRGANFHFQPVQKAGASKTG------LCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSL 1710
P + +GA TG L S PP P+ P P + +
Sbjct: 4582 GCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPT--PPPSVQQKMV 4639
Query: 1711 AKCSPDQELSFPKNKEAASSQESEDSLR 1738
+P +EL K+AAS+++SE +LR
Sbjct: 4640 NGVTPSEELG-EHPKDAASARDSERALR 4666
Score = 40.4 bits (93), Expect = 0.035
Identities = 86/374 (22%), Positives = 121/374 (32%), Gaps = 60/374 (16%)
Query: 3537 GRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKR 3596
G+ L+ LE P NE P P P + PL P P E +P + +
Sbjct: 420 GKAGVQLEPQLEAPLNEEMPLLPPP---EESPLS---PPP------EESPTSPPPEASRL 467
Query: 3597 RAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRS 3656
P +P E L + E S E P + S P + S
Sbjct: 468 SPPPEELPASP--LPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL--EESPLSPP 523
Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKT 3716
S PS AL+ P+ P L+P E+ + P + P + S P ++
Sbjct: 524 EESPPSPALETPLSPPPEASPLSPPF----EESPLSPPPEELPTSPPPEASRLSPPPEES 579
Query: 3717 GGGSQPQPASGQLQSETATTPAKPSFPSR--SPAPERLPARAQAKSCTKGPREAGEQGPH 3774
P P + + P F SP PE P P EA P
Sbjct: 580 P--MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP--------PPEASRLSPP 629
Query: 3775 GSLGPKEKGESSTKRKKGQVPGP--ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPT 3832
P++ S + P P +R + R P++ P +P P PT
Sbjct: 630 ----PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP-----PPEESPT 680
Query: 3833 KPKPNS-------QNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPK------R 3879
P P + ++ P PP E A P +D L + PLL P+ R
Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASP---PPEDSLMSLPLEESPLLPLPEEPQLCPR 737
Query: 3880 GTAVH-GAEPAEPH 3892
H P EPH
Sbjct: 738 SEGPHLSPRPEEPH 751
Score = 40.4 bits (93), Expect = 0.035
Identities = 29/83 (34%), Positives = 34/83 (40%), Gaps = 3/83 (3%)
Query: 590 ESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHP--QETGSP 647
ESP P P T + + S + A P E S P PL PS PPT P + P
Sbjct: 4882 ESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP-ASPPTEPLVELPTEP 4940
Query: 648 FPSPEPPHSLPTHYQPEPAKAFP 670
P P LP PE A+ P
Sbjct: 4941 LAEPPVPSPLPLASSPESARPKP 4963
Score = 39.7 bits (91), Expect = 0.060
Identities = 73/330 (22%), Positives = 113/330 (34%), Gaps = 74/330 (22%)
Query: 3619 EKEVSSSHM-----VSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP-VHPR 3672
+K++ + H+ +E R +G P G + + AS P A P V P+
Sbjct: 3062 KKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPK 3121
Query: 3673 KAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSG-SPRPGTKTGGGSQPQPASGQLQS 3731
G P ATPK +P P++ G +PG G + +G S
Sbjct: 3122 VEEGGRHPSPCQ------FTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSS 3175
Query: 3732 ETAT-----------------TPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQ--G 3772
T TP+ S P S E+ + A + GP +G++
Sbjct: 3176 SGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDK 3235
Query: 3773 PHGSLGPKE---------KGESSTKRKKGQV----------------------PGPARSE 3801
SL E + E +KK Q+ PGPA++
Sbjct: 3236 MESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAM 3295
Query: 3802 SVGSFGRAPSAPDKPPRT------PRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPG 3855
S+ G +PS + R+ P ++PT+P P + R PS + G
Sbjct: 3296 SLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQP-PAHALQQRLAPSMAMVSNQG 3354
Query: 3856 HTQRKDRLGKA--FPQ--GRPLLRPPKRGT 3881
H G+A PQ +P+L GT
Sbjct: 3355 HMLSGQHGGQAGLVPQQSSQPVLSQKPMGT 3384
Score = 36.2 bits (82), Expect = 0.66
Identities = 92/426 (21%), Positives = 125/426 (29%), Gaps = 53/426 (12%)
Query: 3458 PGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPS 3517
P E+ PP LS + L E +P + P E P P R P
Sbjct: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLS----PPPEELPTSPPPEASRLSPPPE 577
Query: 3518 NHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPG 3577
PPP SP R + + P E SP SP P + P P
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Query: 3578 ARGQDAEG------KRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEG 3631
+ + +PL + P +P E+ E S E
Sbjct: 638 PPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP--PEESPTSPPPEASRLSPPPED 695
Query: 3632 GPRGTFHKGSATKPAGCQSSSKDRSAASTP---SKALKFPVHPRKAVGSLAPGELARGTE 3688
P + S P + S S P S L P P+ S P R E
Sbjct: 696 SPTSPPPEDSPASPP------PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749
Query: 3689 NGMKPATPKAKPGPSSQGSG-SPRPGTKT---------------GGGSQPQPASGQL--Q 3730
+ P + P ++ SP+P G PQP L Q
Sbjct: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ 809
Query: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPR----------EAGEQGPHGSLGPK 3780
+E P P SP PE Q++ PR E P P+
Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPE 869
Query: 3781 EKGESSTKRKKGQVPGPARSESVGSFGR-APSAPDKPPRTPRKQATPSRVLPTKPKPNSQ 3839
E G+ + P P G A S P +PP +P + P L +P+
Sbjct: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELP---LSPSGEPSLS 926
Query: 3840 NKPRPP 3845
+ PP
Sbjct: 927 PQLMPP 932
Score = 36.2 bits (82), Expect = 0.66
Identities = 73/305 (23%), Positives = 107/305 (35%), Gaps = 68/305 (22%)
Query: 3617 QKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQS--SSKDRSAASTPSKALKFPVHPRKA 3674
Q++++VS H GG G GS+++ + + S P + + P++
Sbjct: 4100 QQQQQVSLLHTAG-GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQP 4158
Query: 3675 VGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETA 3734
+ L R +N P PK PGP Q SG PG P GQL+++
Sbjct: 4159 M-------LERPMQNNTGPQPPK--PGPVLQ-SGQGLPGVGI------MPTVGQLRAQLQ 4202
Query: 3735 TTPAK-PSFPSRSPAPE---------RLPARAQAKSCTKGPREAGEQG------------ 3772
AK P SP + R ++QA T +E G Q
Sbjct: 4203 GVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQ 4262
Query: 3773 ----PHGSLGP-KEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPS 3827
P GP +E G + ++P P + S G P P PP +P++ PS
Sbjct: 4263 LGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPV-LGPVHPTPPPSSPQEPKRPS 4321
Query: 3828 RV-------------LPTKPKPNSQNKP--RPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
++ PT P P PPP + P Q D L F +G
Sbjct: 4322 QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPG---RVSPAAAQLADTL---FSKGLG 4375
Query: 3873 LLRPP 3877
PP
Sbjct: 4376 PWDPP 4380
Score = 35.8 bits (81), Expect = 0.86
Identities = 74/355 (20%), Positives = 117/355 (32%), Gaps = 33/355 (9%)
Query: 2235 ESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGA---PPHTNP 2291
E P PLA +P G ++Q P P PQ PP P
Sbjct: 4039 EGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLP 4098
Query: 2292 DRMPRGHS---SYSPSNTARLGHREGQAVTAVP---TEPPTLQGAGPDSPACLEGEMGTS 2345
+ + S + + +LG ++VP +P G P S + +G
Sbjct: 4099 GQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT--QNLLGPQ 4156
Query: 2346 SKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQ---SDSPQSHRNAS 2402
E P TG P + G+G + Q + +PQ +
Sbjct: 4157 QPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSP 4216
Query: 2403 HQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRH 2462
Q Q L Q Q+S+ ++ P E G G + C+ F GP
Sbjct: 4217 QQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPL-QGLLGCQPQLGGF-PGPQTGPL 4274
Query: 2463 KARKHRPHP-GAPAEPSPAAL----PAQQPLEPLAQKCQP--PRKKSHRVS-GKERPNHS 2514
+ P P G P P+P P P+ P P P++ S S + P +
Sbjct: 4275 QELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEA 4334
Query: 2515 RGDPSH---------VTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTP 2560
+ P+H +PPP + S + + S+ L P P ++ + + P
Sbjct: 4335 QLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
Score = 35.4 bits (80), Expect = 1.1
Identities = 94/387 (24%), Positives = 132/387 (34%), Gaps = 86/387 (22%)
Query: 3223 SPGDPWGQEGEAKKDSPGERAKPRARSTPSNP---DGAATP---DSASATALADAGS--- 3273
SP P +E R P +P++P D A+P DS + L ++
Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728
Query: 3274 PGPPRTTP-------SPSPDPWAGGEPLLQATPVHEACKDPSRDCHHCGKRFPKPFKLQR 3326
P P+ P SP P+ EP L P E P + H P+P +
Sbjct: 729 PEEPQLCPRSEGPHLSPRPE-----EPHLSPRP-EEPHLSPQAEEPHLS---PQP---EE 776
Query: 3327 HLAVHSPQRVYLCPRC--PRVYPEHGELLAHLGGAHGLLERPELQHTPLYACELCATVMR 3384
P+ +L P+ P + P+ EL HL E P L P C +
Sbjct: 777 PCLCAVPEEPHLSPQAEGPHLSPQPEEL--HLSPQ---TEEPHLSPVPEEPC-----LSP 826
Query: 3385 IIKKSFACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFRGVRRPGAPGQKARALEGTLPS 3444
++S + H++ L + P + R + P PGQ E L
Sbjct: 827 QPEESHLSPQSEEPCLSPRPEESHLSPELE--KPPLSPRPEKPPEEPGQCPAPEELPL-- 882
Query: 3445 KRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLER--P 3502
P PGE P P LSE P L L E+ P + G P + P
Sbjct: 883 ----------FPPPGEPSLSPLLGEPALSEPGEPPLSPLPEEL-PLSPSGEPSLSPQLMP 931
Query: 3503 VDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALERP---ENEASPGSP 3559
DP+ P L PP+LSP G LE P + ++ P SP
Sbjct: 932 PDPLPPP-----LSPIITAAAPPALSPL--------------GELEYPFGAKGDSDPESP 972
Query: 3560 --GPLLQQALPLGASLPRPGARGQDAE 3584
P+L+ + P P A D E
Sbjct: 973 LAAPILETPIS-----PPPEANCTDPE 994
Score = 34.7 bits (78), Expect = 1.9
Identities = 106/467 (22%), Positives = 149/467 (31%), Gaps = 113/467 (24%)
Query: 1098 LTQGPREDEPQKPRKAARQEAGGDG---APANPEEPGGSRPGPGRSPQARGPSRSLETGA 1154
LT + EPQ P R + AP+ P P RPG P A+ P L
Sbjct: 2331 LTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPP---LTPRP 2387
Query: 1155 AAREGGPKCADRPSVAPKDPL-QVPTNTETSEETR--------------PSLDFPQ-EAK 1198
CA P P DP +VP + ++ ++ PS P+ ++
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSP 2447
Query: 1199 EPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLL----------------------- 1235
+P + S P S + L PP E+ G L
Sbjct: 2448 DPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELH 2507
Query: 1236 --IPEQPPPSRHDT-------GTPKPSGSLANTA-----------------PHGSSPTPG 1269
+P PP+ + GTP P A PHG + G
Sbjct: 2508 AKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFG 2567
Query: 1270 VGSLLGGPGGTQAPVS----HNSKDPPARQPGEF-----LAPVANPSSTACPKPSVLSSK 1320
G LG P T V+ H S P G L+P+ PS P P
Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY 2627
Query: 1321 ISSFGCDPAGFNRDPLGVPVAKK---GPQPYSSPHSELFLGPKD-----LAGCFLEELHP 1372
+S +G PV K+ G SS + G +D L+ LE+
Sbjct: 2628 LSHGASQRSGITS-----PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQ 2682
Query: 1373 KPSARD---APPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEP----------GRAASP 1419
+ R+ + L Q+ E A + + PPG+ EP G+
Sbjct: 2683 RQRLRELLIRQQIQRNTLRQEKETAAAAAGAV--GPPGSWGAEPSSPAFEQLSRGQTPFA 2740
Query: 1420 PTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPS 1466
T + SSL LP + P+ G S D L + PP PS
Sbjct: 2741 GTQDKSSLV-GLPPSKLSGPILGPGSFPSDDRL----SRPPPPATPS 2782
Score = 33.9 bits (76), Expect = 3.3
Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 14/135 (10%)
Query: 424 DTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLP 483
D+E AA GP + P T + P P G + S+ +G P + P+
Sbjct: 12 DSEPAADGPAASEDPSA---TESDLPNPHVGEV----SVLSSGSPRLQETPQDCSGGPVR 64
Query: 484 WPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK-LPAVRSSQG 542
+ PS HG L R P P S G +PGP E LP+ SQ
Sbjct: 65 RCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGG------SPGPNEAVLPSEDLSQI 118
Query: 543 GSPALFTYNGMTDPG 557
G P T + +PG
Sbjct: 119 GFPEGLTPAHLGEPG 133
Score = 33.1 bits (74), Expect = 5.6
Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 24/84 (28%)
Query: 582 RVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHP 641
R + A P E P P P SP++ SPA+P +E PL PT P
Sbjct: 4904 RQLSAPPPEEPSPPP------------SPLAPSPASPPTE------PL-----VELPTEP 4940
Query: 642 QETGSPFPSPEPPHSLPTHYQPEP 665
P PSP P S P +P+P
Sbjct: 4941 L-AEPPVPSPLPLASSPESARPKP 4963
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 94.0 bits (232), Expect = 3e-18
Identities = 269/1192 (22%), Positives = 370/1192 (31%), Gaps = 240/1192 (20%)
Query: 5 RPRGAPPPTMTGDLQPRQVASS------PGHPSQPPLEDNTPATRTTKGAREAGGQAQAM 58
+P G PP + L P+ A + G P P + P T A +AG
Sbjct: 354 KPAGVLPPKLY-QLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLS 412
Query: 59 ELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTP---------------------- 96
P A QA + P + G AP PG P +
Sbjct: 413 GFP-APALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQ 471
Query: 97 ---PGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTP 153
PG +Q P +L+ Q IL A+ T L P A +
Sbjct: 472 FLLPGAPAVQLPQQLSALPANVGGQ--ILAAAAPHTGGQLIANPILTNQNLAGPLSLGPV 529
Query: 154 QGPGTGA---------PLRPGLPR--------------TEAQPAAEELGFHRCFQ----- 185
P +GA P++ G P T++QPA Q
Sbjct: 530 LAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLP 589
Query: 186 --------------EPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPL--------QPGS 223
+P + +T +P T +P PP PL QP
Sbjct: 590 PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649
Query: 224 YPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGA 283
P QA+ PP A P + PE I G P +P + Q
Sbjct: 650 APTPQAAA----PPQATTPQPSPGLA---SSPEKIVLGQPPSATPTAILTQDSLQMFLPQ 702
Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAV------GTGPAYP-LPTQPAPSP-L 335
P G + V P P A G GP P PAP+P +
Sbjct: 703 ERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQI 762
Query: 336 PCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTR 395
P G G SSP H AP DS H L P RPPS +
Sbjct: 763 PAAAPLKG--------PGPSSSPSLPHQAP--LGDSPH--LPSPHPTRPPSRPPSRPQSV 810
Query: 396 GPPSSLPQRH----------FPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTA 445
P S P H PG + + P + APGPP L P
Sbjct: 811 SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPE 870
Query: 446 APYPTPPGGPLAATRSMFFNGQ------PSPGQRLCLPQSAPLPWPQVLPTARPSPHGME 499
P P P P ++T S + P+P Q P P PT P+ H
Sbjct: 871 GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLH--- 927
Query: 500 MLSRLPFPAGGPEWQGGSQGALGTAGKT-PGPREKLPA---------VRSSQGGSPAL-- 547
+P PA P + + T P P+ L +++ GG+PA
Sbjct: 928 ---LVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQ 984
Query: 548 --FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPS--PATNTAGS 603
+ +T P A L G A P GTP+ P A + + LP PA N A +
Sbjct: 985 TSTSLGPLTSPAASVLVSGQA-----PSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFA 1039
Query: 604 ----TCSSLSPMSSSPANPSS--EESQLPG-----PLGPS--AFFHPPTHPQETG----- 645
T + SS P PS ES+L G L PS A F H +
Sbjct: 1040 SNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPD 1099
Query: 646 --SPFPSPEPP--HSLPTH-YQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRG 700
+ FPS E LP H YQ A P P+D + F+ + + +
Sbjct: 1100 YKTAFPSFEDALHRLLPYHVYQG----ALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKY 1155
Query: 701 GLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARA 760
L + P+ + Q + +++ + GL +A +
Sbjct: 1156 RLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAAS 1215
Query: 761 KDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSL 820
+GH+ P S P A P H T L+ A G SL
Sbjct: 1216 SEGHRLPGHGPLSSSAPGASTQPPP-------HLPTKLVIRHGGAGGSPSVTWARASSSL 1268
Query: 821 AATPFPLPA-SDLDMEDDAKLDSLITEALNGMEYQS---------DNPEIDSSFIDVFAD 870
+++ A S LD ++D + S + E +S + + D
Sbjct: 1269 SSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALD 1328
Query: 871 EEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLG 930
P P+ T + PPP P P P G P P+ + LG
Sbjct: 1329 PVHQPPPPPA-----------TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLG 1377
Query: 931 LAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSG---GGGRA----------SG 977
AP P + K +R+++ GA EG+ +G GG A SG
Sbjct: 1378 TAPHCPRLPLR----------KTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSG 1427
Query: 978 L---RPRRNDGLGER----PPPRPRRPRTQAPGSRADPAPRVPRAAALPEET 1022
L D L +R PPP P Q G AP +P A E+
Sbjct: 1428 LIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSES 1479
Score = 65.9 bits (159), Expect = 8e-10
Identities = 120/477 (25%), Positives = 159/477 (33%), Gaps = 104/477 (21%)
Query: 1107 PQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAARE---GGPKC 1163
PQ P + G P + P P PQA P S ++ + G P
Sbjct: 625 PQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
Query: 1164 ADRPSVAPKDPLQVPTNTETSEETR----PSLDFPQEA--KEPETAEESAPDSTEFTEAL 1217
A ++ +D LQ+ E S++ P L P P A++ AP +T +
Sbjct: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAP-ATPVAKGA 743
Query: 1218 RSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGP 1277
P A + +P IP P P S SL + AP G SP L P
Sbjct: 744 GLGPQAPDSQASPAPAPQIPAAAPLKGPG---PSSSPSLPHQAPLGDSPH------LPSP 794
Query: 1278 GGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSF------GCDPAGF 1331
T+ P PP+R P P + P CP P + F G P
Sbjct: 795 HPTRPP-----SRPPSR-PQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPAS 848
Query: 1332 NRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDG 1391
N P A PQP P S+ GP P A PP+S+S
Sbjct: 849 NP----APTAPGPPQPPLRPQSQPPEGPL-------------PPAPHLPPSSTSSAVASS 891
Query: 1392 EDAGSLEP---------QLPRS--------PPGTAETEPGRAASPP----TLES-SSLFP 1429
+ S P Q P S PP T P AA PP T + ++ FP
Sbjct: 892 SETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFP 951
Query: 1430 DLP-----VDRFDPPLYGSLSANRDSGLPFAC---------------------ADPPQKT 1463
LP ++RF G + N+ G P A A T
Sbjct: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011
Query: 1464 VPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPSLPGKGSG 1520
PS P P+ + + P+LP+ K + P V AA S PGK SG
Sbjct: 1012 APSHAPAPAPMAATGLPPLLPAE------NKAFASNLPTLN--VAKAASSGPGKPSG 1060
Score = 53.5 bits (127), Expect = 4e-06
Identities = 300/1364 (21%), Positives = 432/1364 (31%), Gaps = 283/1364 (20%)
Query: 1119 GGDGAPANPE-----EPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKD 1173
GG GA + P +P PG G SP P+ L + P P +
Sbjct: 308 GGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLT 367
Query: 1174 PLQ-VPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASP 1232
P P + + P PQ+ K P+ A L PA P
Sbjct: 368 PKPFAPAGATLTIQGEPGA-LPQQPKAPQNLTFMAAGKAGQNVVLSGFPA---------P 417
Query: 1233 GLL--IPEQPPPSRHDTGTPKPSGSLANTAP-----HGSSPTPGVGSLLGG------PGG 1279
L + +QPP + P+P G+L+ GSS +L G PG
Sbjct: 418 ALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA 477
Query: 1280 TQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVP 1339
+ PA G+ LA A + +L+++ + AG PL +
Sbjct: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQ------NLAG----PLSL- 526
Query: 1340 VAKKGP--QPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSL 1397
GP P+S HS L + +P+ P + + AGSL
Sbjct: 527 ----GPVLAPHSGAHSAHILSAAPIQV-------GQPALFQMPVSLA---------AGSL 566
Query: 1398 EPQLPRSPPGTAETEPGRAAS-PPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFAC 1456
Q +P G A T + + PP+ + PD V P +A P
Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATP------AAATGEAAPVLT 620
Query: 1457 ADPPQKTVPS-DPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPSLP 1515
P + P+ P P L L++ P P T P PG A S P
Sbjct: 621 VQPAPQAPPAVSTPLP--LGLQQPQAQQPPQAPTPQAAAPPQATTPQPS---PGLASS-P 674
Query: 1516 GK---GSGCSVALMSHLSEDELEI--------QKLVTELESQLQRSKDTRGAPRELAEAE 1564
K G S + L++D L++ Q L E + AP +
Sbjct: 675 EKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPA 734
Query: 1565 SVGRVELGTGTEPPSQRRTCQAT-VPHEDTFSAADLTRVGESTAHREGAESAVATVEAVQ 1623
V G G P Q QA+ P +AA L G S++ ++
Sbjct: 735 PATPVAKGAGLGP--QAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQA--------- 783
Query: 1624 GRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGASKTGLCQAE 1683
P G P S HP P ++ VS P P H P +A + G+ +
Sbjct: 784 --PLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPP---LHPCPPPQAPPTLPGIFVIQ 838
Query: 1684 GDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSF-----PKNKEAASSQESEDSLR 1738
P P P+ PGP P+ L P + +A + SE S R
Sbjct: 839 NQLGVPPPASNPAPTA-PGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSR 897
Query: 1739 LLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLD-------A 1791
L P F + + PH+ P P +HL P+ A APP
Sbjct: 898 L-PAPTPSDFQLQFPPSQGPHKSPTPP-----PTLHLVPEPA-----APPPPPPRTFQMV 946
Query: 1792 TWPFGASPSHAA--QGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVP 1849
T PF A P A + +G L AG APA + T+ L P
Sbjct: 947 TTPFPALPQPKALLERFHQVPSGIILQNKAGG--------APAAPQTSTS-------LGP 991
Query: 1850 VPSPAC---VSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPR 1906
+ SPA VS PS P+ +P P P A +L + A+ P
Sbjct: 992 LTSPAASVLVSGQAPSGTPTAPSHAPA------PAPMAATGLPPLLPAENKAFASNLP-- 1043
Query: 1907 VNPSGLEGGTVEGGKVAC-GPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQ 1965
T+ K A GP G P G+Q + + L+ L K Q
Sbjct: 1044 ---------TLNVAKAASSGP--GKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQ 1092
Query: 1966 G--------------QGTANQLQPEN---GVSPGGTDNH--------ASVNASPKTALTG 2000
G + ++L P + G P +D H S +T
Sbjct: 1093 GSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAML 1152
Query: 2001 PTEGAVLLEKCKGSRAA--------MSLQEE----------AEPTPSPPSPNRESLALAL 2042
+LLE+ + + M +QEE A+ P + SL L +
Sbjct: 1153 NKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPI 1212
Query: 2043 TAAHSRSGSEGRTPERASSPGLNK---PLLAT---------GDSPAPSVGDLAACAPSPT 2090
A+ G P +S+PG + P L T G SP+ + ++ S +
Sbjct: 1213 AASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSS 1272
Query: 2091 SAAHMPCSL-----GPLP-REDPLTSPSRAQGGLGGQLPAS---------------PSCR 2129
S++ SL GP+P R P A+ +G +L P +
Sbjct: 1273 SSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQ 1332
Query: 2130 DPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPS--LTTSPCDPKEALAGCLL 2187
PP P L P P T P AP L T+P P+ L
Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR 1392
Query: 2188 QGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAG 2247
+ G P P P G G +P ++ E ATS +
Sbjct: 1393 ENVGGP-GAPEGTPAGRAR-------GGSPAPLPAKVDE-------------ATSGLIRE 1431
Query: 2248 AVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPP-----HTNPDRMPRGHSSYS 2302
+ + L P A A +G PD ++ G PP +PD SS S
Sbjct: 1432 LAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDS 1491
Query: 2303 PSNTARLGH-----------REGQAVTAVPTEPPTLQGAGPDSP 2335
P + H ++ T P+ P P SP
Sbjct: 1492 PQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASP 1535
Score = 53.5 bits (127), Expect = 4e-06
Identities = 124/531 (23%), Positives = 175/531 (32%), Gaps = 105/531 (19%)
Query: 3411 KHLRGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPG----------- 3459
+H+ G+ F PGAP + LP+ + +AP G
Sbjct: 463 QHMLPGQNQFLL-----PGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTN 517
Query: 3460 EDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNH 3519
++ P P+L+ S H+ S A G P + PV + LP+
Sbjct: 518 QNLAGPLSLGPVLAPHSGAHSAHILS--AAPIQVGQPALFQMPVS-----LAAGSLPTQS 570
Query: 3520 QECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGAR 3579
Q P PAA L G P A +P L+Q A P A+
Sbjct: 571 QPAPAG-----PAATT------VLQGVTLPPSAVAMLNTPDGLVQPATPAAAT------- 612
Query: 3580 GQDAEGKRAP-LVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFH 3638
G+ AP L +AP A P Q+ Q + + + P+ T
Sbjct: 613 -----GEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQ---AAAPPQAT-- 662
Query: 3639 KGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGEL------ARGTENGMK 3692
+P+ +SS ++ P A + + ++ P E A G +
Sbjct: 663 ---TPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVP 719
Query: 3693 ---------------PATPKAK------PGPSSQGSGSPRPGTKTGGGSQ-PQPASGQLQ 3730
PATP AK P SQ S +P P + P P+S
Sbjct: 720 ASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779
Query: 3731 SETATTPAKPSFPSRSPA--PERLPARAQAKSCTKGPREAG-EQGPHGSLGPKEKGESST 3787
A P PS P P R P+R Q S ++ P E P P G
Sbjct: 780 PHQAPLGDSPHLPSPHPTRPPSRPPSRPQ--SVSRPPSEPPLHPCPPPQAPPTLPGIFVI 837
Query: 3788 KRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPS 3847
+ + G VP PA + AP+AP P R Q+ P P P P + P PPS
Sbjct: 838 QNQLG-VPPPASNP-------APTAPGPPQPPLRPQSQP----PEGPLPPA---PHLPPS 882
Query: 3848 EQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHRTAE 3898
A ++ RL P L PP +G H + P H E
Sbjct: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGP--HKSPTPPPTLHLVPE 931
Score = 50.8 bits (120), Expect = 3e-05
Identities = 237/1085 (21%), Positives = 345/1085 (31%), Gaps = 228/1085 (21%)
Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGA 1154
E EL GP + +P G GA A P PG T
Sbjct: 121 EAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPG--------------STDL 166
Query: 1155 AAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214
+G P ++ P P V + + + +P + P+
Sbjct: 167 LGLQGPPTVLTHQALVP--PQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNG---- 220
Query: 1215 EALRSPPAACAGEMGASP---------------GLLIPEQPPPSRHDTGTPKPSGSL--- 1256
SP A A +G +P L+ +Q P S + PS +
Sbjct: 221 ----SPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLA 276
Query: 1257 -ANTAPHGS------------SPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPV 1303
A +P G+ + T S+ GG G AP S P A PG +P+
Sbjct: 277 SAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPL 336
Query: 1304 ANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLA 1363
P P+V+ + P P GV L PK
Sbjct: 337 V-------PAPNVILHR------TPTPIQPKPAGV------------------LPPK--- 362
Query: 1364 GCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLE 1423
L +L PKP A PA ++ Q + G+L PQ P++P G+A L
Sbjct: 363 ---LYQLTPKPFA----PAGATLTIQG--EPGAL-PQQPKAPQNLTFMAAGKAGQNVVL- 411
Query: 1424 SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPML 1483
S P L + F P + A PPQ P LL + S ++
Sbjct: 412 SGFPAPALQANVFKQPPATTTG-----------AAPPQPPGALSKPMSVHLLNQGSSIVI 460
Query: 1484 PSHFPDLSGGKVLSKTCPPERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTEL 1543
P+ + L P + +P +LP G +A + + +L ++T
Sbjct: 461 PAQHMLPGQNQFLLPGAPAVQ--LPQQLSALPANVGGQILAAAAPHTGGQLIANPILTN- 517
Query: 1544 ESQLQRSKDTRGAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLT--- 1600
+ LA S+G V PH SA L+
Sbjct: 518 --------------QNLAGPLSLGPV-----------------LAPHSGAHSAHILSAAP 546
Query: 1601 -RVGESTAHREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSG----A 1655
+VG+ + A ++ Q +P P + G L P A L +
Sbjct: 547 IQVGQPALFQMPVSLAAGSL-PTQSQPAPAGPAATTVLQG-VTLPPSAVAMLNTPDGLVQ 604
Query: 1656 PFSPRGANFHFQPVQKAGASKTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSP 1715
P +P A PV + QA P + L +P Q PQ A +P
Sbjct: 605 PATPAAATGEAAPVLTVQPAP----QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAA--AP 658
Query: 1716 DQELSFPKNKEAASSQE----------------SEDSLRLLPCEQRGGFLPEPGTADQPH 1759
Q + + ASS E ++DSL++ ++R +P +A+ PH
Sbjct: 659 PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERS---QQPLSAEGPH 715
Query: 1760 RGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFG-ASPSHAAQGHSAGRAGGHLHPT 1818
PA +P P A L P ASP+ A Q +A G
Sbjct: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG----- 770
Query: 1819 AGRPGFEGNEFAPAGASSL--TAPRGREAWLVPVPSPACVSNTHPSRRS--QDPALSPPI 1874
PG P+ + SL AP G L P P P + PSR P PP+
Sbjct: 771 ---PG-------PSSSPSLPHQAPLGDSPHL-PSPHPTRPPSRPPSRPQSVSRPPSEPPL 819
Query: 1875 RQLQLPGPGVAKSKDGILGLQE---LTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSP 1931
P P + GI +Q + P A +P P + + GP +P
Sbjct: 820 H--PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAP 877
Query: 1932 GGVQVTTLPAVAGH---QLGLEADGHWGLLGQAEKTQGQGTAN------QLQPENGVSPG 1982
+T AVA L A Q +QG + L PE P
Sbjct: 878 HLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPP 937
Query: 1983 GTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPP------SPNRE 2036
+ +P AL P LLE+ + + LQ +A P+ P P
Sbjct: 938 PPPRTFQMVTTPFPALPQP---KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS 994
Query: 2037 SLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMP 2096
A L + + SG+ P A +P P+ ATG P + A + PT
Sbjct: 995 PAASVLVSGQAPSGTP-TAPSHAPAPA---PMAATGLPPLLPAENKAFASNLPTLNVAKA 1050
Query: 2097 CSLGP 2101
S GP
Sbjct: 1051 ASSGP 1055
Score = 49.3 bits (116), Expect = 8e-05
Identities = 92/359 (25%), Positives = 124/359 (34%), Gaps = 54/359 (15%)
Query: 78 LRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLA---GRAEGSPPQRYILGIASSRTKPTLD 134
L G P S+ S Q PP P++L G A GSP + ASS +
Sbjct: 1221 LPGHGPLSSSAPGASTQPPP-----HLPTKLVIRHGGAGGSPSVTWAR--ASSSLSSSSS 1273
Query: 135 ETPENPQLEAAQ---LPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRC----FQEP 187
+ L+A + +P + P A R GL Q A H +P
Sbjct: 1274 SSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQP 1333
Query: 188 PSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASG-ADSWPPAAENSFPGA 246
P + P P PP P Q GT P + PE + G A P
Sbjct: 1334 PPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRE 1393
Query: 247 NFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAF 306
N G P A PE P G GGSP P PA +T ++A +
Sbjct: 1394 NVGGPGA-PEGTPAGRARGGSPA------PLPAKVDEATSGLIRELAA-------VEDEL 1439
Query: 307 HQP--QGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSA 364
+Q +G PE A P AP G P R S+ + A+ S+
Sbjct: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAP-------GLPPAKRRKSE---SPDVDQASFSS 1489
Query: 365 PRPFSDSLHKSLTKIL---------PERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRAS 414
P D+L + L + P R P+ ++ G P+S P H P +AY S
Sbjct: 1490 DSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRP-EAYPPS 1547
Score = 47.8 bits (112), Expect = 2e-04
Identities = 203/930 (21%), Positives = 289/930 (31%), Gaps = 181/930 (19%)
Query: 522 GTAGKTPGPREKLPAVRSSQGGSP---ALFTYNGMTDPGAQPL----FFGVAQPQVSPHG 574
G GP E P +S G SP L ++ A L FG A +P G
Sbjct: 261 GYLASAAGPSE--PVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTG 318
Query: 575 TPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634
TPS P V S +P+P + +P+ PA G L P +
Sbjct: 319 TPSGQPLAVAPGLGSSPLVPAPNVILHRTP----TPIQPKPA----------GVLPPKLY 364
Query: 635 FHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEG 694
P G+ P +LP QP+ + F A G + L P P
Sbjct: 365 QLTPKPFAPAGATLTIQGEPGALPQ--QPKAPQNLTFMAAGKAGQNVV--LSGFPAPALQ 420
Query: 695 PEVGRGGLQGFPRAPPPYPT-----------------------------HHFSLSSASLD 725
V + A PP P + F L A
Sbjct: 421 ANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAV 480
Query: 726 QLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPAD 785
QL L+ + LAA H G L+A +Q GP L P AP
Sbjct: 481 QLPQQLSALPANVGGQILAAAAPHTG--GQLIANPILTNQNLAGPLSL-GPVLAP----- 532
Query: 786 AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDD-AKLDSLI 844
H+G +H+ L A P++ G P+L P L A L + A
Sbjct: 533 -HSG--AHSAHILSAA---------PIQVG-QPALFQMPVSLAAGSLPTQSQPAPAGPAA 579
Query: 845 TEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPP----P 900
T L G+ + ++ + P+ G ++ P+ + V P +APP P
Sbjct: 580 TTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAA--PVLT---VQPAPQAPPAVSTP 634
Query: 901 LPAATPDPQTPRPGDRGCP-ARGRPKTRSLGLAPTEADAPSQ---GRQQRRGKQLKLFRK 956
LP PQ +P P A P+ + +P A +P + G+ L +
Sbjct: 635 LPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQD 694
Query: 957 DLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRT----------QAPGSRA 1006
L E S L + + PP + P T QAP S+A
Sbjct: 695 SLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQA 754
Query: 1007 D--PAPRVPRAA-----------ALPEETRSSRRRRLP---PRKDPRKRKARGGAWGKEL 1050
PAP++P AA +LP + LP P + P + +R + +
Sbjct: 755 SPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRP- 813
Query: 1051 ILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKP 1110
SE PPP+ P P P
Sbjct: 814 ----------------PSEPPLHPCPPPQAP-------------------------PTLP 832
Query: 1111 RKAARQEAGGDGAPA-NPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSV 1169
Q G PA NP P P PQ++ P L A S
Sbjct: 833 GIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSS 892
Query: 1170 APKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMG 1229
L PT ++ + PS P ++ P P+ A PP +M
Sbjct: 893 ETSSRLPAPTPSDFQLQFPPS-QGPHKSPTPPPTLHLVPE-----PAAPPPPPPRTFQMV 946
Query: 1230 ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSK 1289
+P +P+ P + + PSG + G+ P + LG A V + +
Sbjct: 947 TTPFPALPQ--PKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQ 1004
Query: 1290 DPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGP---- 1345
P AP P + A P +L ++ +F + N A GP
Sbjct: 1005 APSGTPTAPSHAPAPAPMA-ATGLPPLLPAENKAFASNLPTLN----VAKAASSGPGKPS 1059
Query: 1346 -QPYSSPHSELFLGP---KDLAGCFLEELH 1371
Y S S L P CFLE LH
Sbjct: 1060 GLQYESKLSGLKKPPTLQPSKEACFLEHLH 1089
Score = 47.4 bits (111), Expect = 3e-04
Identities = 186/843 (22%), Positives = 266/843 (31%), Gaps = 149/843 (17%)
Query: 1757 QPHRGAPAPE-AFGSPAVHLAPDLAFQGDG------APPLDATWPFGASPSHAAQG---- 1805
QP G P A G+ AV P F G PP T P
Sbjct: 135 QPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSV 194
Query: 1806 ----HSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHP 1861
G L P G G +P GA++ T A + V P NT
Sbjct: 195 QPFLQPVGLGNVTLQPIPGLQGLPNG--SPGGATAATLGL---APIQVVGQPVMALNTPT 249
Query: 1862 SR--RSQDP------ALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLE 1913
S+ Q P + + P + L GV+ G++ + L+ A + L
Sbjct: 250 SQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATT-------LN 302
Query: 1914 GGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQL 1973
G +V GG A G+P G + P + L A T +
Sbjct: 303 GNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLV-----------PAPNVILHRTPTPI 351
Query: 1974 QPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSP 2033
QP+ P G +PK + A +L + EP P P
Sbjct: 352 QPK----PAGVLPPKLYQLTPKPF----------------APAGATLTIQGEPGALPQQP 391
Query: 2034 NRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAA 2093
+ A G+ + G P L P A P P A
Sbjct: 392 KAPQNLTFMAA--------GKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGAL 443
Query: 2094 HMPCSLGPLPREDPLTSPSRAQGGLGGQ----LPASPSCRDPPGPQQLLACSPAWAPLEE 2149
P S+ L + + P AQ L GQ LP +P+ + P QQL A P
Sbjct: 444 SKPMSVHLLNQGSSIVIP--AQHMLPGQNQFLLPGAPAVQLP---QQLSAL-----PANV 493
Query: 2150 ADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSA-V 2208
+ A +A P LT + LAG L G P+ P S G+ SA +
Sbjct: 494 GGQILAAAAPHTGGQLIANPILTN------QNLAGPLSLG---PVLAPHS---GAHSAHI 541
Query: 2209 TCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAV--RATGLSSTPTG 2266
+ + ++P L A + P A V V + A + +TP G
Sbjct: 542 LSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDG 601
Query: 2267 ------DEAQAGRGLP----GPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQA 2316
A G P P PQ APP + S LG ++ QA
Sbjct: 602 LVQPATPAAATGEAAPVLTVQPAPQ---APP--------------AVSTPLPLGLQQPQA 644
Query: 2317 VTAVPTEPPTLQGAGPDSPACLEGEMG-TSSKEPEDPGTPETGRSGATKMPRVTCPSTGL 2375
P + PT Q A P + G SS E G P + AT +T S +
Sbjct: 645 QQ--PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPS----ATPTAILTQDSLQM 698
Query: 2376 GLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQW 2435
L + + +++ S + S P DP + ++G P + ++
Sbjct: 699 FLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV---AKGAGLGPQAPDSQAS 755
Query: 2436 KGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALP-------AQQPL 2488
AP P + S P L PH +P P + P ++ P
Sbjct: 756 PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815
Query: 2489 EPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP-PPAQGSKEVLRAPGSPHSQQLHP 2547
EP C PP+ + G + G P + P P A G + P S + P
Sbjct: 816 EPPLHPCPPPQAPP-TLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLP 874
Query: 2548 PSP 2550
P+P
Sbjct: 875 PAP 877
Score = 47.4 bits (111), Expect = 3e-04
Identities = 98/414 (23%), Positives = 135/414 (32%), Gaps = 47/414 (11%)
Query: 2025 EPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAA 2084
+P P P L L L ++ + TP+ A+ P P + G + +P L
Sbjct: 622 QPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQ 681
Query: 2085 CAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAW 2144
+ +A SL ++ P A+G +PAS PP Q +P
Sbjct: 682 PPSATPTAILTQDSLQMFLPQERSQQPLSAEGP-HLSVPASVIVSAPPPAQDPAPATP-- 738
Query: 2145 APLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPS---SWP 2201
GA P AP S SP + A L+G G P PS P
Sbjct: 739 ------------VAKGAGLGPQAPDS-QASPAPAPQIPAAAPLKGPG-PSSSPSLPHQAP 784
Query: 2202 PGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLS 2261
G + H P R SR E P PP A P + V L
Sbjct: 785 LGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS--EPPLHPCPPPQAPPTLPGIFVIQNQLG 842
Query: 2262 -STPTGDEAQAGRGLPGPDPQSRGAP--------PHTNPDRMPRGHSSYSPSNTA----- 2307
P + A G P P + + P PH P +S S +++
Sbjct: 843 VPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPT 902
Query: 2308 ----RLGHREGQAVTAVPTEPPTL----QGAGPDSPACLEGEMGTSSKEPEDPGTPETGR 2359
+L Q PT PPTL + A P P +M T + P P P+
Sbjct: 903 PSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVT-TPFPALP-QPKALL 960
Query: 2360 SGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGP 2413
++P G G AP ++ S SP + S Q P G P P
Sbjct: 961 ERFHQVPSGIILQNKAG-GAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAP 1013
Score = 47.4 bits (111), Expect = 3e-04
Identities = 103/422 (24%), Positives = 143/422 (33%), Gaps = 112/422 (26%)
Query: 3424 GVRRPGA--PGQKARALEGTLPSKRRRVAMPGSAPGPGE---DRPPPRGSSPILSEGSLP 3478
G+++P A P Q P PG A P + +PP + IL++ SL
Sbjct: 638 GLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQ 697
Query: 3479 ALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAA-LADG 3537
L P + +G L P + PPP+ P PA +A G
Sbjct: 698 MFLPQERSQQPLSAEG--PHLSVPASVIV-------------SAPPPAQDPAPATPVAKG 742
Query: 3538 RGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRR 3597
G + P+++ASP +P P +P A L PG + +APL S
Sbjct: 743 AGL-----GPQAPDSQASP-APAP----QIPAAAPLKGPGPSSSPSLPHQAPLGDS---- 788
Query: 3598 APGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSA 3657
H H T+P + S+ +S
Sbjct: 789 ----------PHLPSPH---------------------------PTRPPS-RPPSRPQSV 810
Query: 3658 ASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSP--RPGTK 3715
+ PS+ P P +A +L PG + G+ P P + P P++ G P RP
Sbjct: 811 SRPPSEPPLHPCPPPQAPPTL-PGIFVIQNQLGVPP--PASNPAPTAPGPPQPPLRP--- 864
Query: 3716 TGGGSQPQPASGQLQSETATTPAKPS--FPSRSPAPERLPARAQAKSCTKGPREAGEQGP 3773
Q QP G L P+ S S S RLPA + + P QGP
Sbjct: 865 -----QSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPS---QGP 916
Query: 3774 HGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTK 3833
H S P VP PA + P PPRT + TP LP +
Sbjct: 917 HKSPTPPPTLHL--------VPEPA------------APPPPPPRTFQMVTTPFPALP-Q 955
Query: 3834 PK 3835
PK
Sbjct: 956 PK 957
Score = 46.6 bits (109), Expect = 5e-04
Identities = 81/363 (22%), Positives = 124/363 (34%), Gaps = 50/363 (13%)
Query: 1091 EKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSL 1150
E+ ++ +GP P +A A D APA P G GP P+ +
Sbjct: 703 ERSQQPLSAEGPHLSVPASVIVSAPPPAQ-DPAPATPVAKGAGL-GPQAPDSQASPAPAP 760
Query: 1151 ETGAAAREGGPKCADRPSVAPKDPL----QVPTNTETSEETRPSLDFPQEAKEPETAEES 1206
+ AAA GP + PS+ + PL +P+ T +RP PQ P +
Sbjct: 761 QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPP-SRPQSVSRPPSEPPL 819
Query: 1207 APDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSP 1266
P ++PP PG+ + ++ G P P+ + A TAP P
Sbjct: 820 HP-----CPPPQAPPTL--------PGIFV------IQNQLGVPPPASNPAPTAP--GPP 858
Query: 1267 TPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGC 1326
P + P G P H P + VA+ S T+ P+ S
Sbjct: 859 QPPLRPQSQPPEGPLPPAPH-------LPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP 911
Query: 1327 DPAGFNRDPLGVPVAKKGPQPYSSPHS-----ELFLGP---KDLAGCFLEELHPKPS--- 1375
G ++ P P P+P + P ++ P LE H PS
Sbjct: 912 PSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGII 971
Query: 1376 ----ARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDL 1431
A AP A + + + + P T P A +P + ++ L P L
Sbjct: 972 LQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLL 1031
Query: 1432 PVD 1434
P +
Sbjct: 1032 PAE 1034
Score = 45.8 bits (107), Expect = 8e-04
Identities = 90/419 (21%), Positives = 137/419 (32%), Gaps = 68/419 (16%)
Query: 3453 GSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRG 3512
GS P + P ++ +L +LP S VA T P+ L +P P
Sbjct: 564 GSLPTQSQPAPAGPAATTVLQGVTLPP-----SAVAMLNT---PDGLVQPATPAAATGEA 615
Query: 3513 CELPSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGAS 3572
P L+ PA A L L++P+ + P +P P Q A P A+
Sbjct: 616 A-----------PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTP--QAAAPPQAT 662
Query: 3573 LPRPG----------ARGQDAEGKRAPLVFSGKRRA--PGARGRCAPDHFQEDHL-LQKE 3619
P+P GQ ++ + P R + P + HL +
Sbjct: 663 TPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ-QPLSAEGPHLSVPAS 721
Query: 3620 KEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA 3679
VS+ + P KG+ P S + A P+ A P K G +
Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA------PLKGPGPSS 775
Query: 3680 PGELARGTENGMKPATPKAKPG-----PSSQGSGSPRPGTKTGGGSQPQPASGQ------ 3728
L G P P P P S+ RP ++ P P +
Sbjct: 776 SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835
Query: 3729 -LQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESST 3787
+Q++ P + +P P + P R Q++ P PH +S+
Sbjct: 836 VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQP----PEGPLPPAPHLPPSSTSSAVASS 891
Query: 3788 KRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPP 3846
++P P S+ F P + P K TP L P+P + P PPP
Sbjct: 892 SETSSRLPAPTPSDFQLQF--------PPSQGPHKSPTPPPTLHLVPEPAA---PPPPP 939
Score = 42.4 bits (98), Expect = 0.009
Identities = 150/659 (22%), Positives = 204/659 (30%), Gaps = 150/659 (22%)
Query: 331 APSPLPCYQGQPGGLNRHSDLSGALSSPGAA-HSAPRPFSDSLHKSLTKILPERPPSAQD 389
A +P GQP + S + +P H P P L L + P
Sbjct: 313 ASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFA 372
Query: 390 GLGST---RGPPSSLPQRHFPGQ--AYRASG-----VDTSPGP-PDTELAAPGPPPARLP 438
G+T +G P +LPQ+ Q + A+G V S P P + PPA
Sbjct: 373 PAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATT- 431
Query: 439 QLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWP-QVLPTARPSPHG 497
T A P PPG L+ S+ Q G + +P LP Q L P+
Sbjct: 432 -----TGAAPPQPPGA-LSKPMSVHLLNQ---GSSIVIPAQHMLPGQNQFLLPGAPAVQL 482
Query: 498 MEMLSRLPFPAGGPEWQGGSQGALGTAGKTP--------GPREKLPAVRSSQG------- 542
+ LS LP GG + G P GP P + G
Sbjct: 483 PQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHIL 542
Query: 543 -------GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLP-------PPRVVGASP 588
G PALF G+ P Q Q +P G + PP V
Sbjct: 543 SAAPIQVGQPALFQMPVSLAAGSLP-----TQSQPAPAGPAATTVLQGVTLPPSAVAMLN 597
Query: 589 SESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPF 648
+ L PAT A +T + ++ PA + P PLG P Q +P
Sbjct: 598 TPDGLVQPAT-PAAATGEAAPVLTVQPAPQAPPAVSTPLPLG----LQQPQAQQPPQAPT 652
Query: 649 PSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRA 708
P P P P P+ GL + L + P + + LQ F
Sbjct: 653 PQAAAP----------PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMF--- 699
Query: 709 PPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSP 768
L Q +R+ L+A H ++ A
Sbjct: 700 ---------------LPQ----------ERSQQPLSAEGPHLSVPASVIVSA-------- 726
Query: 769 GPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLP 828
PP P+ AP P AGL A D+QA P +P+ A P P
Sbjct: 727 -PP--PAQDPAPATPVAKGAGLGPQAP------DSQASPAPAPQ----IPAAAPLKGPGP 773
Query: 829 ASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSK 888
+S + A L D+P + S PS P+ S P +
Sbjct: 774 SSSPSLPHQAPL--------------GDSPHLPSPHPTRPPSRPPSRPQSVSRP-PSEPP 818
Query: 889 AGVTPESKAPP--------------PLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAP 933
P +APP P PA+ P P P P + +P L AP
Sbjct: 819 LHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAP 877
Score = 38.9 bits (89), Expect = 0.10
Identities = 88/381 (23%), Positives = 123/381 (32%), Gaps = 71/381 (18%)
Query: 958 LDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPR-PRRPRTQAPGSRADPAPRVPRAA 1016
L ++EG G G S P G +PPP P + + G+ P+ RA+
Sbjct: 1210 LPIAASSEGHRLPGHGPLSSSAP----GASTQPPPHLPTKLVIRHGGAGGSPSVTWARAS 1265
Query: 1017 ALPEETRSSRR---------------RRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061
+ + SS R PP K R G L LKI Q+
Sbjct: 1266 SSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIG------LKLKIKQEAGLS 1319
Query: 1062 REYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGD 1121
+ + + PPP +++ + P P P
Sbjct: 1320 KVVHNTALDPVHQPPPPPAT--------------LKVAEPPPRPPPPPPPTGQMNGTVDH 1365
Query: 1122 GAPANPE-EPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTN 1180
PA PE +P G+ P R P R R G A EG P A R PL +
Sbjct: 1366 PPPAAPERKPLGTAPHCPRLP-LRKTYRENVGGPGAPEGTP--AGRARGGSPAPLPAKVD 1422
Query: 1181 TETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPP---AACAGEMGASPGLLIP 1237
TS R E +A + + L+ PP AA A + P P
Sbjct: 1423 EATSGLIR---------------ELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAP 1467
Query: 1238 EQPPPSRHDTGTPK-PSGSLANTAP-------HGSSPTPGVGSLLGGPGGTQAP-VSHNS 1288
PP R + +P S ++ +P H S + +L PG T AP H +
Sbjct: 1468 GLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAA 1527
Query: 1289 KDPPARQPGEFLAPVANPSST 1309
P P A P S+
Sbjct: 1528 SAGTPASPPPLHRPEAYPPSS 1548
Score = 38.1 bits (87), Expect = 0.17
Identities = 44/146 (30%), Positives = 53/146 (36%), Gaps = 14/146 (9%)
Query: 3693 PATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSP----- 3747
PAT K P P G G P PA+ + + T P P P R
Sbjct: 1337 PATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE-RKPLGTAPHCPRLPLRKTYRENV 1395
Query: 3748 ----APERLPA-RAQAKSCTKGPREAGE--QGPHGSLGPKEKGESSTKRKKGQVPGPARS 3800
APE PA RA+ S P + E G L E E + KG P PA S
Sbjct: 1396 GGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVED-ELYQRMLKGPPPEPAAS 1454
Query: 3801 ESVGSFGRAPSAPDKPPRTPRKQATP 3826
+ G+ AP PP RK +P
Sbjct: 1455 AAQGTGDPDWEAPGLPPAKRRKSESP 1480
Score = 37.4 bits (85), Expect = 0.30
Identities = 51/213 (23%), Positives = 71/213 (33%), Gaps = 37/213 (17%)
Query: 1070 SEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPR----KAARQEAGGDGAP- 1124
+E +PPP P G + + P P PR K R+ GG GAP
Sbjct: 1343 AEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPE 1402
Query: 1125 ---ANPEEPGGSRPGPGRSPQA--------------------RGPSRSLETGAAAREGGP 1161
A G P P + +A +GP AA G P
Sbjct: 1403 GTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462
Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEF------TE 1215
+ P + P + + + ++ S D PQ+ E + + T
Sbjct: 1463 DW-EAPGLPPAKRRK--SESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTP 1519
Query: 1216 ALRSPPAACAGEMGASPGLLIPEQPPPSRHDTG 1248
A P AA AG + P L PE PPS H+ G
Sbjct: 1520 APSYPHAASAGTPASPPPLHRPEAYPPSSHNGG 1552
Score = 33.9 bits (76), Expect = 3.3
Identities = 81/342 (23%), Positives = 109/342 (31%), Gaps = 62/342 (18%)
Query: 333 SPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLG 392
SP + L+ S S A SS A P P + RPP
Sbjct: 1256 SPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRN------------RPPIKTYEAR 1303
Query: 393 STRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPP 452
S G + Q + + +D PP PPPA L P P P PP
Sbjct: 1304 SRIGLKLKIKQEAGLSKVVHNTALDPVHQPP--------PPPATLKVAEPPPRPPPPPPP 1355
Query: 453 GGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPE 512
G + T P P P+ PL +PH RLP E
Sbjct: 1356 TGQMNGTVD-----HPPPAA----PERKPLG---------TAPH----CPRLPLRKTYRE 1393
Query: 513 WQGGSQGALGT-AGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVA-QPQV 570
GG GT AG+ G + + S + + D Q + G +P
Sbjct: 1394 NVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAA 1453
Query: 571 SP-HGT-------PSLPPPRVVGASPSESPLPSPATNTAGSTCS-SLSPMSSSPANPSSE 621
S GT P LPP + SESP A+ ++ S +L+ S +
Sbjct: 1454 SAAQGTGDPDWEAPGLPPAK---RRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILN 1510
Query: 622 ESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQP 663
Q PG P++P + P+ PP P Y P
Sbjct: 1511 LQQAPGRTPA------PSYPHAASAGTPASPPPLHRPEAYPP 1546
Score = 32.3 bits (72), Expect = 9.5
Identities = 41/156 (26%), Positives = 51/156 (32%), Gaps = 49/156 (31%)
Query: 2746 PAEDSSRAHSRSEEGVWEENTPPLGP-------------------LGFPETSSSPADSTT 2786
P SR SR + + PPL P LG P +S+PA +
Sbjct: 796 PTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAP 855
Query: 2787 SSCLQGLPDNPDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRN 2846
P P + Q PEGP P A PPS V+ S T R
Sbjct: 856 G------PPQPPLRPQSQPPEGPLPPAPHL----PPSSTSSAVASSSE-------TSSR- 897
Query: 2847 PHVYGKRCEKPVLPLPTQPSFEEGGDPTLGPARLPT 2882
LP PT F+ P+ GP + PT
Sbjct: 898 ------------LPAPTPSDFQLQFPPSQGPHKSPT 921
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 93.6 bits (231), Expect = 3e-18
Identities = 257/1053 (24%), Positives = 331/1053 (31%), Gaps = 188/1053 (17%)
Query: 1 MPG-ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED--NTPATRTTKGAREAGGQAQA 57
+PG + P+G P T Q + PG P P L P + G + + G
Sbjct: 462 IPGVDGPKGEPGLLCT---QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518
Query: 58 MELPEAQPRQARDGELKPPSLRGQA-----PSSTPGKRGSP--QTPPGRSPLQAPSRLAG 110
LP G+ P L+G+ P G G P + PGR L G
Sbjct: 519 TGLPGFPGFPGAQGD---PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575
Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGP-GTGAPLRPGLPRT 169
+G P + L ++ + P +P P P GP G G PGL T
Sbjct: 576 -VKGLPGPKGELALSGEKGDQGPPGDPGSPGS-----PGPAGPAGPPGYGPQGEPGLQGT 629
Query: 170 EAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQ--PGSYPEY 227
+ P A PP S S TP P PGPP G Q PG
Sbjct: 630 QGVPGAPG---------PPGEAGPRGELSVS-TPVPGPPGPPGPPGHPGPQGPPGIPGSL 679
Query: 228 QASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSR--PGGSPR-GVSFQFPFPALHGA 283
G P P E PG F PP PKG + PG G + P L G
Sbjct: 680 GKCGDPGLPGPDGEPGIPGIGFPGPPG-----PKGDQGFPGTKGSLGCPGKMGEPGLPGK 734
Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQP 342
P A GP F +G E P P LP P L +G P
Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794
Query: 343 GGLNRHSDLSGALSSPGAAHSAPR-----PFSDSLH-------KSLTKILPERPPSAQDG 390
G G PG PR P + L K+ K P P + G
Sbjct: 795 G----QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850
Query: 391 LGSTRGPPS---------SLPQRHFPGQA--------------YRASGVDTSPGPPDT-- 425
G P L QR +PG G PGPP
Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910
Query: 426 ---ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPL 482
+ +PG P + Q P A G P + S + PG L A
Sbjct: 911 TPGQRGSPGIPGVK-GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG----LKGFAGN 965
Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK--------- 533
P + P G++ L LP PAG P G +G LG+ G P +
Sbjct: 966 PGEKG-NRGVPGMPGLKGLKGLPGPAGPP----GPRGDLGSTGNPGEPGLRGIPGSMGNM 1020
Query: 534 -LPAVRSSQG--------GSPALFTYNGMTDPGAQPLFFGVAQP-QVSPHGTPSLPPPRV 583
+P + +G G P L +G+ +P + +P P G P LP
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080
Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSS-PANPSSEESQ----LPGPLGPSAFFHPP 638
+ P P AG + SP S P P + G LGP PP
Sbjct: 1081 KKGEMGQ-PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139
Query: 639 THPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVG 698
P GSP P + P PA G +G L P P P G
Sbjct: 1140 GLPGFPGSPGPMGIRGD--------QGRDGIPGPA---GEKGETGLLRAPPGPRGNP--G 1186
Query: 699 RGGLQGFPRAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLL 756
G +G AP P P ++ A R + + F G +
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAG-------------PRGPTGIEGFPGPPGLPGAI 1233
Query: 757 LA-----RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811
+ R G + SPG PG P PP + + G + H G A G
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293
Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871
L P L P P D + G++ + NP F+
Sbjct: 1294 LGAPGTPGL-----PGPRGDPGF-----------QGFPGVKGEKGNP----GFLGSIGPP 1333
Query: 872 EPSGPRGPSS--GHPLKSKAGVTPESKAPPPLPA-----ATPDPQTPRPGDRG-CPARGR 923
P GP+GP G P K P S PP P P P P PG+ G C RG+
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP-PGNLGPCGPRGK 1392
Query: 924 PKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRK 956
P G T A +G + +G+ LF +
Sbjct: 1393 PGKD--GKPGTPGPAGEKGNKGSKGEPESLFHQ 1423
Score = 86.7 bits (213), Expect = 4e-16
Identities = 353/1494 (23%), Positives = 441/1494 (29%), Gaps = 412/1494 (27%)
Query: 184 FQEPPSSFTSTNYTSPSATPRPPAP----------GPPQSRGTS-----------PLQPG 222
F PP S +T P P P P G RG S P PG
Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPG 112
Query: 223 SYPEYQASGADSWPPA-AENSFPG--ANFGVP--------------PAEPEPIPKGSR-- 263
+ Y G + E FPG G P PA+ E I ++
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172
Query: 264 PG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG-- 319
PG G+P P P G P P G GP P+G E +G
Sbjct: 173 PGLPGAPGPQGLPGP-PGFPGPVGPPGPPGFFGFPGAMGP-----RGPKGHMGERVIGHK 226
Query: 320 --------TGPAYP----LPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAP 365
TGP P + T P +G+ G G G PG ++ +
Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286
Query: 366 R--PFSDSLHKSLTKI-LPERPPSAQDGLGSTRGPPSSLPQRHFPGQ------------- 409
+ P L K +P P S +G+ RG P + + GQ
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGS--EGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344
Query: 410 ----AYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP-YPTPPGGPLAATR---- 460
Y+ G + +PGP PGP AR PQ P+ P P PG R
Sbjct: 345 EYYDTYQEKGDEGTPGP-------PGPRGARGPQ--GPSGPPGVPGSPGSSRPGLRGAPG 395
Query: 461 ------SMFFNGQP------SPGQRLC-----LPQSAPLPWPQ---VLPTARPSPHGME- 499
S G+P +PG C LP S P P V P HG+
Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455
Query: 500 -------------------MLSRLPFPAGGPEWQG-----------GSQGALGTAGKTPG 529
+ ++ P+ G P G G QGA G G
Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515
Query: 530 P-REKLPAVRSSQG--GSPALFTYNGMT-----------DPG--AQPLFFGVAQPQVSPH 573
P LP G G P L G T DPG QP G+ +P
Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP- 574
Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPS 632
G LP P+ A E P G S SP + PA P Q PG G
Sbjct: 575 GVKGLPGPKGELALSGEKGDQGP----PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630
Query: 633 AFFHPPTHPQETG--------SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQC 684
P P E G +P P P P P H P+ P G G
Sbjct: 631 GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---- 686
Query: 685 LEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLA 744
P E G G+ GFP P P F + SL
Sbjct: 687 -----LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG------------------- 721
Query: 745 AFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQ 804
K G PG PGLP P V G T G+
Sbjct: 722 -------------CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG------TPGFPGERG 762
Query: 805 AEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSF 864
G+ + LP L TP E L+G P
Sbjct: 763 NSGEHGEIGLPGLPGLPGTPG-------------------NEGLDGPRGDPGQP------ 797
Query: 865 IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924
P G +GP G ++ G ++ P L Q R G G +G P
Sbjct: 798 -------GPPGEQGP-PGRCIEGPRG----AQGLPGLNGL--KGQQGRRGKTG--PKGDP 841
Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984
L + + S G +G+ L ++ G G L P D
Sbjct: 842 GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR-------------GYPGNPGILGPPGED 888
Query: 985 GL--------GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDP 1036
G+ PP P P T PG R P +P +R P K
Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGT--PGQRGSPG--IPGVKG---------QRGTPGAKGE 935
Query: 1037 RKRKARGGAWGKELILKIVQQKNRLREYDFA-SESEEDEQPPPRGPGFRGRRGRGEKRKE 1095
+ K G G I ++ K FA + E+ + P PG +G +G
Sbjct: 936 QGDK---GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL------ 986
Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155
P P PR G G+ NP EP G R PG P + G
Sbjct: 987 ------PGPAGPPGPR-------GDLGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTL 1032
Query: 1156 AREGGPKCADRPSVAPKDPLQVPTNTE-TSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214
G P A RP + LQ SE TRP P T + P
Sbjct: 1033 ---GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP-------TGDPGLPGD---- 1078
Query: 1215 EALRSPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272
GEMG PG L P P + G+P G PHG G+
Sbjct: 1079 -------MGKKGEMGQPGPPGHLGPAGPEGA---PGSPGSPGLPGKPGPHGDLGFKGIKG 1128
Query: 1273 LLGGPG-----------------GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPS 1315
LLG PG G + + PA + GE A P P
Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP--- 1185
Query: 1316 VLSSKISSFGCDPAGFNRDPLGVP--VAKKGPQPYSSPHS----ELFLGPKDLAGCFLEE 1369
G A +R G P +KG + P E F GP L G +
Sbjct: 1186 ---------GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236
Query: 1370 L---HPKPSARDAP-------PASSSCLCQDGEDAGSLEPQLPRSPPGTAET--EPGRAA 1417
P +R +P P S + G D GS+ P+ PPGTA PGR
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKG-DKGSMGHPGPKGPPGTAGDMGPPGRLG 1295
Query: 1418 SPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLP--FACADPPQKTVPSDPP 1469
+P T P LP R DP G + G P PP P PP
Sbjct: 1296 APGT-------PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342
Score = 77.8 bits (190), Expect = 2e-13
Identities = 289/1237 (23%), Positives = 378/1237 (30%), Gaps = 221/1237 (17%)
Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPIPKGS 262
PGPP + + P + + + D P + PG ++G P
Sbjct: 238 PGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297
Query: 263 RPG-----GSP--RGVSFQFPFPALHGAS-TKPFPADVAGHAFTNGPLVFAFHQPQGAWP 314
+PG G P GV FP L G K D+ F + +Q +G
Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG--- 354
Query: 315 EEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372
+ GP P + PS P G PG + L GA PG S
Sbjct: 355 -DEGTPGPPGPRGARGPQGPSGPPGVPGSPG--SSRPGLRGAPGWPGLKGSKG------- 404
Query: 373 HKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP 432
ER +D +G T G P PG PGPP + GP
Sbjct: 405 ---------ERGRPGKDAMG-TPGSPGCAGSPGLPGSP-------GPPGPPGDIVFRKGP 447
Query: 433 PPAR-LP-QLWDPTAAPYPTPPGGP-LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489
P LP L P P G P L T+ + G P L +P Q
Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507
Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL-----PAVRSSQG-- 542
+ SP G + LP G P QG G G G+T P ++ P +R G
Sbjct: 508 GLKGSP-GSPGNTGLPGFPGFPGAQG-DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565
Query: 543 ---GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH--GTPSLPPPRVVGASPSESPLPSPA 597
G P G+ P + G Q P G+P P P P P P
Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625
Query: 598 TN-TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP--------- 647
T G + P + P S + +PGP GP PP HP G P
Sbjct: 626 LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG---PPGHPGPQGPPGIPGSLGKC 682
Query: 648 ----FPSPEPPHSLPTHYQPEPA-----KAFPFPADGLGAEG------------------ 680
P P+ +P P P + FP LG G
Sbjct: 683 GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742
Query: 681 ----AFQCLEETP-FPHEGPEVGRGGLQGFPRAPP-PYPTHHFSLSSASLD--------Q 726
A TP FP E G G G P P P + L D +
Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802
Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL-----PSPPAAPR 781
C + R L + G R K G + PG PGL P +P
Sbjct: 803 QGPPGRCIEGPRGAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPG 859
Query: 782 VPA-DAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFP-----LPASDLDME 835
+P G L G G+D + P P P P
Sbjct: 860 IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919
Query: 836 DDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT--P 893
T G + NP S V D+ G +G + K GV P
Sbjct: 920 IPGVKGQRGTPGAKGEQGDKGNPG-PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978
Query: 894 ESKAPP--PLPAATPDPQ-----TPRPGDRGCPARGRPKTR-SLGLAPTEADAPSQGRQQ 945
K P PA P P+ T PG+ G RG P + ++G+ ++ + G
Sbjct: 979 GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPG 1036
Query: 946 RRGKQ----LKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQA 1001
R G+ + + D G +EG+ G G P + GL P ++
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG------PTGDPGL---PGDMGKKGEMGQ 1087
Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061
PG P P A S LP + P G G + I K L
Sbjct: 1088 PGPPGHLGPAGPEGAP-----GSPGSPGLPGKPGPH------GDLGFKGI------KGLL 1130
Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR-------GEKRKE--VELTQGPREDEPQKPR 1111
P GP G RG +GR GEK + + GPR + +
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190
Query: 1112 KAARQEAGGDGAP--------ANPEEPGGSR--PGPGRSPQARGPSRSLETGAAAREGGP 1161
K R G G P A P P G PGP P A P ++ G G P
Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250
Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS------TEFTE 1215
AP P ++ + + S+ P P TA + P T
Sbjct: 1251 G-------APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP 1303
Query: 1216 ALRSPPA-----ACAGEMG--------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH 1262
R P GE G PG + P+ PP R D GT K + P
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363
Query: 1263 GSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297
G+ PG+ G GP G P K +PG
Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400
Score = 69.3 bits (168), Expect = 7e-11
Identities = 200/845 (23%), Positives = 263/845 (31%), Gaps = 154/845 (18%)
Query: 477 PQSAPLPWPQVLPTARPSPH-GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR---- 531
PQ LP VL A P+ G + G + + G +G G G +PG +
Sbjct: 9 PQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPG-SPGQKGFTG 67
Query: 532 -EKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASP 588
E LP + +G G P L G+ P F G +P T V G S
Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127
Query: 589 SESP-----LPSPATNTAGSTCSSLSPMSSSPANPSSEESQ------LPGPLGPSAFFHP 637
S+ LP + L +PA E LPG GP P
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187
Query: 638 PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEV 697
P P G P P F FP +G G + E H+G E
Sbjct: 188 PGFPGPVG----------------PPGPPGFFGFPG-AMGPRGPKGHMGERVIGHKG-ER 229
Query: 698 GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLL 757
G GL G P PP V++T D N + L
Sbjct: 230 GVKGLTG-PPGPPG----------------TVIVTLTGPD-NRTDL-------------- 257
Query: 758 ARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817
+ + G + + G PG P P P + G GD +GK
Sbjct: 258 -KGEKGDKGAMGEPGPPGPSGLPGESYGSEKG---------APGDPGLQGK--------- 298
Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877
P P P S+ ++ + L+ E +G++ Q D P G R
Sbjct: 299 PGKDGVP-GFPGSE-GVKGNRGFPGLMGE--DGIKGQK-------------GDIGPPGFR 341
Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPR--PGDRGCPARGRPKTRSLGLAPTE 935
GP+ + + G E PP P PQ P PG G P RP R G
Sbjct: 342 GPTEYYDTYQEKG--DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR--GAPGWP 397
Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP--- 992
S+G + R GK + + G+ +GS G + G D + + PP
Sbjct: 398 GLKGSKGERGRPGKDA------MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451
Query: 993 -------RPRRPRTQA----PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKA 1041
P P PG P +P LP + +P R+ K
Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP-----PRGPGFRGRRGRGEKRKEV 1096
G+ G + + E E QP P PG RG+ GR + +
Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGR-KGLDGI 570
Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAA 1156
T G + K A E G G P +P PG P P GP E G
Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG--EPGLQG 628
Query: 1157 REGGPKCADRPSVA-PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215
+G P P A P+ L V T P P P P +
Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVST---------PVPGPPGPPGPPGHPGPQGPPGIPGSL 679
Query: 1216 ALRSPPAACA--GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273
P GE G PG+ P PP + D G P GSL G PG L
Sbjct: 680 GKCGDPGLPGPDGEPGI-PGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737
Query: 1274 LGGPG 1278
G G
Sbjct: 738 PGAKG 742
Score = 67.4 bits (163), Expect = 3e-10
Identities = 285/1227 (23%), Positives = 374/1227 (30%), Gaps = 204/1227 (16%)
Query: 1682 AEGDSRPPQDVCLPEPS--KQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739
A G+ PP LP S + G D G K D FP E R
Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP-------GSEGVKGNRG 318
Query: 1740 LPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASP 1799
P G + E G Q +G P F P + +G P P G
Sbjct: 319 FP-----GLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-----PPGPRG 366
Query: 1800 SHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVS 1857
+ QG S G G P + RPG G P G+ G++A P SP C
Sbjct: 367 ARGPQGPS-GPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP-GSPGCAG 424
Query: 1858 NTHPSRRSQDPALSPP------------------IRQLQLPGPGVAKSKDGILGLQELTP 1899
+ P PP + +PG K + G+L Q P
Sbjct: 425 S--PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ--CP 480
Query: 1900 AAQSPPRV-NPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958
PP + GL G G+ +GSPG T LP G A G GL
Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP---GAQGDPGLK 537
Query: 1959 GQAEKTQGQGTANQLQPENGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAA 2017
G+ +T LQPE V PG + G T G L KG A
Sbjct: 538 GEKGET--------LQPEGQVGVPGDPGLRGQPGRKGLDGIPG-TPGVKGLPGPKGELAL 588
Query: 2018 MSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077
+ + P P SP A +G G P+ PGL G P
Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPA-------GPAGPPGYGPQ--GEPGLQGTQGVPGAPGPP 639
Query: 2078 SV----GDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133
G+L+ P P P GP P P G LG P P G
Sbjct: 640 GEAGPRGELSVSTPVPGP----PGPPGPPGHPGP-QGPPGIPGSLG--KCGDPGLPGPDG 692
Query: 2134 PQQLLACSPAWAPLEEAD-GVQATTDT----GAEDSPVAP--PSLTTSPCDPKEALAGCL 2186
+ P + D G T + G P P P L + +P A+ G
Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-- 750
Query: 2187 LQGEGS---PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243
G G+ P E +S G + TP + L P R + P P
Sbjct: 751 --GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGP 805
Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302
P P A GL+ G + Q G RG GP +G P DR + S
Sbjct: 806 PGRCIEGPRGAQGLPGLN----GLKGQQGRRGKTGP----KGDPGIPGLDRSGFPGETGS 857
Query: 2303 PSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK--EPEDPGTPETGRS 2360
P G P P L G D + G G P +PGTP G+
Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP--GQR 915
Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420
G+ +P V G+ P + +P + +G+P
Sbjct: 916 GSPGIPGVK--------GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP--------GL 959
Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480
+G+ P N R PG+ K K P P P P
Sbjct: 960 KGFAGNPGEKGN---------------------RGVPGMPGLKGLKGLPGPAGPPGPRGD 998
Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP--PPAQGSKEVLRAPG 2538
P EP + P + + G + + G P +P P G + PG
Sbjct: 999 LGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057
Query: 2539 SPHSQQLHPPSPT-----EHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593
+ PP PT ++ K +P P L P E G
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP----PGHLGPAGPEGAPGSPGSPGLPG 1113
Query: 2594 DSPSHSEGKSNKKRGKLRGRRLREESILP----------VSADVISDGRGSRPSPA---- 2639
H + +G L +R LP + D GR P PA
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD---QGRDGIPGPAGEKG 1170
Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698
A P G P A G + R A PG + G +A G TG + PG
Sbjct: 1171 ETGLLRAPP----GPRGNPGAQGAKGDRGAPGFPG-LPGRKGAMGDAGPRGPTGIEGFPG 1225
Query: 2699 DRMLCPGRMDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757
L + G P G +G+ A G GP + +G+ + GS +
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS-----MGHPGPKG 1280
Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP------DNPDTQGGVQGPEGPTP 2811
G + PP G LG P T P QG P NP G + GP GP
Sbjct: 1281 PPGTAGDMGPP-GRLGAPGTPGLPGPRGDPG-FQGFPGVKGEKGNPGFLGSI-GPPGPI- 1336
Query: 2812 DASGSSAKDPPSLFDDEVSFSQLFPPG 2838
K PP + D + + PG
Sbjct: 1337 -----GPKGPPGVRGDPGTLKIISLPG 1358
Score = 66.6 bits (161), Expect = 5e-10
Identities = 282/1189 (23%), Positives = 366/1189 (30%), Gaps = 225/1189 (18%)
Query: 65 PRQAR--DGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122
PR AR G PP + G SS PG RG+P P + R A G+P
Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP--- 420
Query: 123 GIASSRTKPTLDETPENP-----------------QLEAAQLPEVDTPQG-PG---TGAP 161
G A S P P P L + +P VD P+G PG T P
Sbjct: 421 GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP 480
Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP 221
PG P P G ++ + SP T P PG P ++G L+
Sbjct: 481 YIPGPPGLPGLPGLH--GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538
Query: 222 GSYPEYQASGADSWP--PAAENSFPGANF-----GVPPAEPEPIPKGSRPGGSPRGVSFQ 274
Q G P P PG G P + P PKG +G Q
Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKG--DQ 595
Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSP 334
P P G+ P PA AG P G P+ G +P P P
Sbjct: 596 GP-PGDPGSPGSPGPAGPAG--------------PPGYGPQGEPGLQGTQGVPGAPGP-- 638
Query: 335 LPCYQGQPGGLNRHSDLSGALSSPG-AAHSAPR---PFSDSLHKSLTKILPERPPSAQDG 390
P G G L+ + + G PG H P+ SL K LP P + G
Sbjct: 639 -PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP--GPDGEPG 695
Query: 391 LGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY 448
+ GPP + FPG G PG ++ PG P P L P
Sbjct: 696 IPGIGFPGPPGPKGDQGFPG----TKGSLGCPG----KMGEPGLPGK--PGLPGAKGEPA 745
Query: 449 PTPPGGPLAATRSMFFNGQPS-PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP 507
PGGP G P PG+R HG L LP
Sbjct: 746 VAMPGGP----------GTPGFPGER-----------------GNSGEHGEIGLPGLPGL 778
Query: 508 AGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGV 565
G P G G G G+ P E+ P R +G G+ L NG+ +
Sbjct: 779 PGTP-GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR------ 831
Query: 566 AQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPS---- 619
+ + P G P +P G S P + + G + P+ P NP
Sbjct: 832 -RGKTGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQ-GEMGPLGQRGYPGNPGILGP 884
Query: 620 -SEESQL-----PGPLGPSAFFHPPTHPQETGSP-FPSPEPPHSLPTHYQPEPAKAFPFP 672
E+ + PG +GP P P + GSP P + P + K P P
Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944
Query: 673 AD-----GLGAEGAFQCLEETPFPHEGPEV----GRGGLQGFP-RAPPPYPTHHFSLSS- 721
++ G E + P V G GL+G P A PP P +
Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004
Query: 722 ----------ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG-- 769
S+ + + + F GL G + PG
Sbjct: 1005 PGEPGLRGIPGSMGNMGM-----PGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059
Query: 770 ---PPGLPSPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPF 825
PG P P P +P D G + G A EG + LP
Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----- 1114
Query: 826 PLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPL 885
P P DL + L L + G P P G RG +
Sbjct: 1115 PGPHGDLGFKGIKGL--LGPPGIRGPPGLPGFP----------GSPGPMGIRGDQGRDGI 1162
Query: 886 KSKAGVTPES--KAPPPLPAATPDPQTPRPGDRGCPA-RGRP-KTRSLGLAPTEADAPSQ 941
AG E+ PP P P Q + GDRG P G P + ++G A +
Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221
Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL----GERPPPRPRRP 997
G G + + G GS G G G+ G P P+ P
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281
Query: 998 RTQAPGSRADPAPRVPRAAALPEETRSSRRRRLP-PRKDPRKRKARG--GAWGKELILKI 1054
PG+ D P P + LP PR DP + G G G L
Sbjct: 1282 ----PGTAGDMGP--------PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329
Query: 1055 VQQKNRLREYDFASESEEDEQPPPRGP-GFRGRRGRGEKRKEVELTQGPREDEPQKPRKA 1113
+ P P GP G G RG K + L P P P +
Sbjct: 1330 I------------------GPPGPIGPKGPPGVRGDPGTLKIISLPGSP--GPPGTPGEP 1369
Query: 1114 ARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPK 1162
Q G P P G R PG+ + P + E G +G P+
Sbjct: 1370 GMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPE 1418
Score = 58.9 bits (141), Expect = 9e-08
Identities = 116/476 (24%), Positives = 150/476 (31%), Gaps = 78/476 (16%)
Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488
G PG+K +P + +PG A PG PRG P L + +
Sbjct: 964 GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG-----PRGDLGSTGNPGEPGLRGIPGSMG 1018
Query: 3489 ----PST-----TKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRG 3539
P + T G+P RP P H ++G + + E P P P G
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPG-PPGPTGDPGLPG 1077
Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG----QDAEGKRAPLVFSG 3594
D G + +P G GP P LP +PG G + +G P G
Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137
Query: 3595 KRRAPGARGRCAPDHFQEDHLLQ-----KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649
PG G P + D ++ + + + GPRG G Q
Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN---------PGAQ 1188
Query: 3650 SSSKDRSAASTPS----KALKFPVHPRKAVGSLA-------PGELARGTENGMKPATPKA 3698
+ DR A P K PR G PG + G P +
Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248
Query: 3699 KPG-PSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756
PG P G GS G K GS P P P + P R
Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPG--------------PKGPPGTAGDMGPPGRL 1294
Query: 3757 QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP 3816
A P G GP G P +G K +KG PG +GS G P P P
Sbjct: 1295 GA------PGTPGLPGPRGD--PGFQGFPGVKGEKGN-PG-----FLGSIG--PPGPIGP 1338
Query: 3817 PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
P + P L P S P P + EPG LG P+G+P
Sbjct: 1339 KGPPGVRGDPG-TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393
Score = 46.2 bits (108), Expect = 6e-04
Identities = 119/452 (26%), Positives = 148/452 (32%), Gaps = 83/452 (18%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG+PGQK LP + PG P GS + LP
Sbjct: 57 PGSPGQKGFTGPEGLPGPQGPKGFPG--------LPGLTGSKGVRGISGLPGF------- 101
Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP--PPSLS----PFPAALADGRGDC 3541
S + G P T + GC Q P P +L P A L +G
Sbjct: 102 --SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159
Query: 3542 AL--DGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAP 3599
A D L+ + PG+PGP Q LP P P G P F G P
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGP-------VGPPGPPGFFG---FP 206
Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP---AGCQSSSKDRS 3656
GA G P + ++ + E + GP GT + T P + D+
Sbjct: 207 GAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIV-TLTGPDNRTDLKGEKGDKG 265
Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG-------PSSQGS 3707
A P P P S PGE + G+E G P P + KPG P S+G
Sbjct: 266 AMGEPG-----PPGP-----SGLPGE-SYGSEKG-APGDPGLQGKPGKDGVPGFPGSEGV 313
Query: 3708 GSPR--PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765
R PG G + Q G + P + + E P GP
Sbjct: 314 KGNRGFPGLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-------PPGP 364
Query: 3766 REA-GEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824
R A G QGP G G SS +G P S G GR P +P
Sbjct: 365 RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAG 424
Query: 3825 TPSRVLPTKPKPNSQNKPRPPPS-EQRKAEPG 3855
+P LP P P P PP RK PG
Sbjct: 425 SPG--LPGSPGP-----PGPPGDIVFRKGPPG 449
Score = 43.9 bits (102), Expect = 0.003
Identities = 113/440 (25%), Positives = 133/440 (30%), Gaps = 88/440 (20%)
Query: 3414 RGGRQPFAFRG-VRRPGAPGQKARALEGTLP--SKRRRVAMPGSAPGPGEDRPPPRGSSP 3470
+G R F G RPG PG + P S+ R PG PG P G
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG--LPGDMGKKG 1083
Query: 3471 ILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP------IRGCELPSNHQECPP 3524
+ + P L P G P + P P H I+G P + P
Sbjct: 1084 EMGQPGPPGHL---GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--P 1138
Query: 3525 PSLSPFPAALADG--RGDCALDG----ALERPEN---------EASPGSPGPLLQQALPL 3569
P L FP + RGD DG A E+ E +PG+ G + P
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198
Query: 3570 GASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628
LP R GA G G R P G PG G P
Sbjct: 1199 FPGLPGRKGAMGD--AGPRGPTGIEGFPGPPGLPGAIIPGQ------------------T 1238
Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGT 3687
GP G+ A P G S S P P G + P G L
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA-- 1296
Query: 3688 ENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR-- 3745
P TP PGP PG K G + P G L S P P P
Sbjct: 1297 -----PGTP-GLPGPRGDPGFQGFPGVK---GEKGNP--GFLGSIGPPGPIGPKGPPGVR 1345
Query: 3746 -------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792
SP P P + E G GP G+LGP K K
Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQG------EPGPPGPPGNLGPCGPRGKPGKDGKP 1399
Query: 3793 QVPGPARSE-SVGSFGRAPS 3811
PGPA + + GS G S
Sbjct: 1400 GTPGPAGEKGNKGSKGEPES 1419
Score = 40.8 bits (94), Expect = 0.027
Identities = 117/495 (23%), Positives = 146/495 (29%), Gaps = 74/495 (14%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG PG K LP + +A+ G G P SP + + P E
Sbjct: 571 PGTPGVKG------LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP 624
Query: 3488 APSTTKGWPETLERPVDP-------VTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG 3539
T+G P P + V+ P+ G P P P P P +L G
Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL----G 680
Query: 3540 DCALDGALERPENEAS------PGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF 3592
C D L P+ E PG PGP Q P SL PG G+
Sbjct: 681 KCG-DPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG--------L 731
Query: 3593 SGKRRAPGARGR--CAPDHFQEDHLLQKEKEVSSSH----MVSEGGPRGTFHKGSATKPA 3646
GK PGA+G A E+ S H + G GT P
Sbjct: 732 PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791
Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT-PKAKPG---- 3701
G P + ++ PR A G PG + G + T PK PG
Sbjct: 792 GDPGQPGPPGEQGPPGRCIE---GPRGAQG--LPGLNGLKGQQGRRGKTGPKGDPGIPGL 846
Query: 3702 --------------PSSQGSGSP--RPGTKTGGGSQPQPAS----GQLQSETATTPAKPS 3741
P QG P + G G P G + A P P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 3742 FPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPGP 3797
+P P K P GEQG G+ GP E G+ KG P
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966
Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHT 3857
+ G G K P P L + P P S PG
Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026
Query: 3858 QRKDRLGKAFPQGRP 3872
++ LG GRP
Sbjct: 1027 GKRGTLGFPGRAGRP 1041
Score = 37.7 bits (86), Expect = 0.23
Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 9/115 (7%)
Query: 3176 RGQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAK 3235
RGQ R D G+ G+ V L E A +G + GSPG P G G A
Sbjct: 559 RGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAG 614
Query: 3236 KDSPGERAKPRARSTPS-----NPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285
G + +P + T P G A P + + G PGPP P P
Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Score = 35.0 bits (79), Expect = 1.5
Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%)
Query: 3183 LGDLPG-----GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKD 3237
L LPG G+ G A L S P G A G PG G++GE +
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK-GEKGETLQP 546
Query: 3238 S--------PGERAKPRARST---PSNPDGAATPDSASATALA----DAGSPGPPRTTPS 3282
PG R +P + P P P AL+ D G PG P + S
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606
Query: 3283 PSPDPWAG-------GEPLLQAT 3298
P P AG GEP LQ T
Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGT 629
Score = 35.0 bits (79), Expect = 1.5
Identities = 51/199 (25%), Positives = 65/199 (32%), Gaps = 21/199 (10%)
Query: 1752 PGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRA 1811
PG+ P GAP P G P H+ + +GD + P G P A GR
Sbjct: 1244 PGSRGSP--GAPGPP--GPPGSHV---IGIKGDKGS-MGHPGPKGP-PGTAGDMGPPGRL 1294
Query: 1812 GGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPA 1869
G G PG G P G + +G +L + P + P DP
Sbjct: 1295 GA-----PGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349
Query: 1870 LSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPP-RVNPSGLEGGTVEGGKVACGPAQ 1928
I PGP + G+ G P PP + P G G + GK
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQG----EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405
Query: 1929 GSPGGVQVTTLPAVAGHQL 1947
G G P HQL
Sbjct: 1406 GEKGNKGSKGEPESLFHQL 1424
Score = 32.3 bits (72), Expect = 9.5
Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 28/116 (24%)
Query: 3205 EPAPKHHRGK--RSAGKAAGSPGDPWGQEGEAKKDS----PGERAKPRARSTPS------ 3252
EP P G S G G+PGDP G +G+ KD PG R P
Sbjct: 269 EPGPPGPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327
Query: 3253 --------NPDGAATPDSASAT--ALADAGSPGPP-----RTTPSPSPDPWAGGEP 3293
P G P T D G+PGPP R PS P G P
Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 92.0 bits (227), Expect = 1e-17
Identities = 324/1383 (23%), Positives = 417/1383 (30%), Gaps = 352/1383 (25%)
Query: 31 SQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKR 90
SQ P NT R KG + G +P + R G PP +G P R
Sbjct: 97 SQTPGGGNTNFGRGRKGQKGEPGL-----VPVVTGIRGRPGPAGPPGSQGPRGERGPKGR 151
Query: 91 GSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLE------A 144
P+ P G +G P G+ P P +P + +
Sbjct: 152 PGPRGPQG-------------IDGEP------GVPGQPGAPGPPGHPSHPGPDGLSRPFS 192
Query: 145 AQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPR 204
AQ+ +D G G+ L PG + L + P T P P
Sbjct: 193 AQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGP---------TGPPGEPG 243
Query: 205 PPAP-GPPQSRGTS--PLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKG 261
P P GP SRG P +PG E +G A + PGA G P A P KG
Sbjct: 244 DPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGS--PGAR-GFPGAPGLPGLKG 300
Query: 262 SRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTG 321
R G + P G + P G GP + + P+ A G
Sbjct: 301 HRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPL---GPRGMPGERGR-LGPQGAPGQR 356
Query: 322 PAYPLPTQPAP-SPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKIL 380
A+ +P +P P PL G PG SG +PG A +
Sbjct: 357 GAHGMPGKPGPMGPL----GIPGS-------SGFPGNPGMKGEAGPTGA----------- 394
Query: 381 PERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQL 440
R P G GPP + PG A G D +PG A GP + P
Sbjct: 395 --RGPEGPQGQRGETGPPGPVGSPGLPG----AIGTDGTPG-------AKGPTGS--PGT 439
Query: 441 WDPTAAPYPTPPGGPLAATRSMFFNGQP-SPGQRLCLPQSAPLPWPQVLPTARPSPHGME 499
P + P GP +T GQP PG P + P P PHG++
Sbjct: 440 SGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPG--------VPGFKGEAGPKGEPGPHGIQ 491
Query: 500 MLSRLPFPAG--GPEWQGGSQGALGTAGK--TPGPR-----EKLPAVRSSQG-------- 542
P G GP G+ G G G+ PG R + LP + +QG
Sbjct: 492 GPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSS 551
Query: 543 ------------GSPALFTYNGMT-DPGAQPLFFGVAQPQVSPHGTPSLP----PPRVVG 585
G P L G+T +PG Q + ++ P G P PP +G
Sbjct: 552 GPKGSQGDPGRPGEPGLPGARGLTGNPGVQG-----PEGKLGPLGAPGEDGRPGPPGSIG 606
Query: 586 --ASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ--LPGPLGPSAFFHPPTHP 641
P LP P GS+ P + A + G +GPS PP
Sbjct: 607 IRGQPGSMGLPGP----KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLA 662
Query: 642 QETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGG 701
E G P PT +Q P P P EG + G G
Sbjct: 663 GERGEQGPPG------PTGFQGLPGPPGP--------------------PGEGGKPGDQG 696
Query: 702 LQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAK 761
+ G P A P + +R + + G
Sbjct: 697 VPGDPGAVGPLGPRGERGNPG--------------ERGEPGITGLPGEKGMAG---GHGP 739
Query: 762 DGHQRSPGPPGLP---SPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817
DG + SPGP G P PP +P + AG G+ AEG L
Sbjct: 740 DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799
Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877
P P P + ++ GPR
Sbjct: 800 PGPLGPPGPAGPT--------------------------------------GEKGEPGPR 821
Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEAD 937
G + G E+ + A P +PG +G P G P + D
Sbjct: 822 GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP--GEPGQK--------GD 871
Query: 938 APSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRP 997
A S G Q G A G G GL+ G G + PP
Sbjct: 872 AGSPGPQ-----------------GLAGSPGPHGPNGVPGLK----GGRGTQGPP----G 906
Query: 998 RTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPP--RKDPRKRKARG--------GAWG 1047
T PGS P P A P + PP R DP G G G
Sbjct: 907 ATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPG 966
Query: 1048 KELILKIVQQKNRLREYDFASESEEDEQPPPRGP----GFRGRRG-------RGEKRKEV 1096
+ + ED QP P GP G G+RG RGE + +
Sbjct: 967 DK------------------GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGE--RGM 1006
Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLET---- 1152
GP P K A GD P P P GS GP P GP+ + T
Sbjct: 1007 PGLPGP----AGTPGKVGPTGATGDKGPPGPVGPPGSN-GPVGEPGPEGPAGNDGTPGRD 1061
Query: 1153 GAAAREG-----GPKCADRPSVAPKDPLQVPTNTETSEETRP---------------SLD 1192
GA G GP AP P V + + P L
Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP 1121
Query: 1193 FPQ-----EAKEPETAEESAPDSTEFT--EALRSPPAACAGEMGAS--PGLLIPEQPPPS 1243
PQ + + + FT + L PP GE G++ PG P PP
Sbjct: 1122 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP-NGEQGSAGIPGPFGPRGPP-- 1178
Query: 1244 RHDTGTPKPSGSLANTAPHGSSPTPGV-GSLLGGPGGTQAPVSHNSKDPPARQPGEFLAP 1302
G PSG N P G PGV GS+ G G + P P PG A
Sbjct: 1179 ----GPVGPSGKEGNPGPLGPIGPPGVRGSV--GEAGPEGPPGEPGPPGPPGPPGHLTAA 1232
Query: 1303 VAN 1305
+ +
Sbjct: 1233 LGD 1235
Score = 79.0 bits (193), Expect = 9e-14
Identities = 284/1159 (24%), Positives = 349/1159 (30%), Gaps = 223/1159 (19%)
Query: 1751 EPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGR 1810
EPG QP GAP P G P+ H PD + PF A + + G
Sbjct: 163 EPGVPGQP--GAPGPP--GHPS-HPGPD-----------GLSRPFSAQMAGLDEKSGLGS 206
Query: 1811 AGGHLHPTAGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPAL 1870
G + + G G P G L +G T P DP
Sbjct: 207 QVGLMPGSVGPVG-------PRGPQGLQGQQGG------------AGPTGPPGEPGDPGP 247
Query: 1871 SPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGS 1930
PI GP +DG G G E G A+G
Sbjct: 248 MGPIGSRGPEGPPGKPGEDG------------------EPGRNGNPGEVGFAGSPGARGF 289
Query: 1931 PGGVQVTTLPAVAGHQLGLEAD----GHWGLLGQAEKTQGQGTANQLQP-----ENG-VS 1980
PG + L GH+ GLE G G G+A T G L P E G +
Sbjct: 290 PGAPGLPGLKGHRGHK-GLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG 348
Query: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPS----------- 2029
P G + P GP G + + G ++ EA PT +
Sbjct: 349 PQGAPGQRGAHGMP--GKPGPM-GPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG 405
Query: 2030 ---PPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD--SPAP--SVGDL 2082
PP P G++G T SPG + P + G SP P S G
Sbjct: 406 ETGPPGPVGSPGLPGAIGTDGTPGAKGPT----GSPGTSGPPGSAGPPGSPGPQGSTGPQ 461
Query: 2083 AACA-PSPTSAAHMPCSLGPLPREDP--LTSPSRAQGGLGGQLP-ASPSCRDPPGPQQLL 2138
P GP P + P G G + P P PPGP
Sbjct: 462 GIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGER 521
Query: 2139 ACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP----KEALAGCL-------L 2187
+P +DG+ E PV S DP + L G +
Sbjct: 522 G-APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGV 580
Query: 2188 QGE-------GSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKE--KLWES-- 2236
QG G+P ED PPGS+ P L P+ S + K E+
Sbjct: 581 QGPEGKLGPLGAPGEDGRPGPPGSIGI------RGQPGSMGLPGPKGSSGDPGKPGEAGN 634
Query: 2237 ---PGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAG----RGLPGPD--PQSRGAPP 2287
PG+ +P G V PS V GL+ G++ G +GLPGP P G P
Sbjct: 635 AGVPGQRGAPGKDGEVGPSGPVGPPGLAGE-RGEQGPPGPTGFQGLPGPPGPPGEGGKPG 693
Query: 2288 HTNPDRMPRGHSSYSP-SNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSS 2346
P P G R +T +P E G GPD P G GT
Sbjct: 694 DQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT-- 751
Query: 2347 KEPEDPGTPE-TGRSGATKMPRVTCPSTGL-GLGRTTAPSSTASDFQSDSPQSHRNASHQ 2404
P D G P G G + P G+G A + +D P
Sbjct: 752 --PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLP------GPL 803
Query: 2405 TPQGDPLGPQDLKQR--SRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRH 2462
P G P GP K RG P S N +G+ +GP A F G
Sbjct: 804 GPPG-PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGE--NGPTG----AVGFAGPQGPDGQ 856
Query: 2463 KARKHRPHPGAPAEPSPAALPAQQPLE----PLAQKCQPPRKKSHRVSGKERPNHSRGDP 2518
K PG P + A P Q L P P K G G
Sbjct: 857 PGVK--GEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSA 914
Query: 2519 SHVTQPPP--AQGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHP 2576
V P P A G L PG L + V + PA P + D
Sbjct: 915 GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGED 974
Query: 2577 KQAEKREGRRWRREPTVDSPSHSEGKSNKKR--GKLRGRRLREESILPVSADVISDGRGS 2634
Q P D P G + ++ G R R LP A G
Sbjct: 975 GQ------------PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPA-----GTPG 1017
Query: 2635 RPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQ 2694
+ P A+ P + G GE P GP +G D GE G +
Sbjct: 1018 KVGPTGATGDKGPPGPVGPPGSNGPVGEPGPE----GPAGNDGTPGRDG---AVGERGDR 1070
Query: 2695 KPPGDRMLCPGRMDGAALGEQPTGQKG-ASARGFWGPRETKALGVCKESGSEPAEDSSRA 2753
PG L PG GA P G G A RG G R P RA
Sbjct: 1071 GDPGPAGL-PG-SQGAPGTPGPVGAPGDAGQRGDPGSR-------------GPIGPPGRA 1115
Query: 2754 HSRSEEGVWEENTPPLGPLGFPETSSSPADSTTS-----SCLQGLPDNPDTQG-----GV 2803
R G P GP G D + LQGLP P G G+
Sbjct: 1116 GKRGLPG-------PQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGI 1168
Query: 2804 QGPEGP--TPDASGSSAKD 2820
GP GP P G S K+
Sbjct: 1169 PGPFGPRGPPGPVGPSGKE 1187
Score = 77.4 bits (189), Expect = 3e-13
Identities = 230/869 (26%), Positives = 273/869 (31%), Gaps = 162/869 (18%)
Query: 1 MPGER-PRGAPPPT----MTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQA 55
M GE P GA P G+ P SPG P D TP + G+ G
Sbjct: 385 MKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGT-DGTPGAKGPTGSPGTSGPP 443
Query: 56 QAMELPEA---------QPRQARDGELKPPSLRGQA-PSSTPGKRG--SPQTPPGRSPLQ 103
+ P + Q + + G+ P +G+A P PG G P PPG +
Sbjct: 444 GSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR 503
Query: 104 APSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLR 163
P G G P G +R P D P + + P + G P R
Sbjct: 504 GPRGDPGTV-GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGR 562
Query: 164 PGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGS 223
PG P P A L + Q P +P RP PG RG QPGS
Sbjct: 563 PGEP---GLPGARGLTGNPGVQGPEGKLGPLG--APGEDGRPGPPGSIGIRG----QPGS 613
Query: 224 Y--PEYQASGADSWPP--AAENSFPGANFGVPPAEPEPIPKG--SRPG--------GSPR 269
P + S D P A PG G P + E P G PG G P
Sbjct: 614 MGLPGPKGSSGDPGKPGEAGNAGVPGQR-GAPGKDGEVGPSGPVGPPGLAGERGEQGPPG 672
Query: 270 GVSFQ-FPFP-ALHGASTKPFPADVAGHAFTNGPLVFAFHQPQG--------------AW 313
FQ P P G KP V G GPL P+G
Sbjct: 673 PTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPL-----GPRGERGNPGERGEPGITGL 727
Query: 314 PEE---AVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSD 370
P E A G GP P + P PS P G PG L G G A P P D
Sbjct: 728 PGEKGMAGGHGPDGPKGS-PGPSGTPGDTGPPG-------LQGMPGERGIA-GTPGPKGD 778
Query: 371 SLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAP 430
+ E+ G RG P L PG A +G PGP
Sbjct: 779 RGG------IGEKGAEGTAGNDGARGLPGPLGP---PGPA-GPTGEKGEPGPR----GLV 824
Query: 431 GPPPARLPQLWDPTAAPYPTPPG-----GPLAATRSMFFNGQPS-PGQRLCLPQSAPLPW 484
GPP +R +P + P G GP G+P PGQ+ A P
Sbjct: 825 GPPGSR----GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQK----GDAGSPG 876
Query: 485 PQVLPTARPSPHGMEMLSRLPFPAGGPEWQG--------GSQGALGTAGKTPGPREKLPA 536
PQ L P PHG + +P GG QG GS G +G G P P
Sbjct: 877 PQGL-AGSPGPHGP---NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPL 932
Query: 537 VRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSP 596
+ G P L DPG+ G P P G P G + P P P
Sbjct: 933 GEPGKEGPPGL-----RGDPGSHGRV-GDRGPAGPPGGPGDKGDPGEDGQPGPDGP-PGP 985
Query: 597 ATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHS 656
A T + P LPGP G P + G P P P +
Sbjct: 986 AGTTGQRGIVGMPGQRGERGMPG-----LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSN 1040
Query: 657 LPTHYQPEPAKAFPFPADGL-GAEGAF-----------------QCLEETPFPHEGPEVG 698
P EP P DG G +GA Q TP P P G
Sbjct: 1041 GPVG---EPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAP--G 1095
Query: 699 RGGLQGFP--RAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCG 754
G +G P R P PP L + D + DR HR F G
Sbjct: 1096 DAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKG------HRGFTG 1149
Query: 755 LLLARAKDGHQRSPGPPGLPSPPAAPRVP 783
L G G G+P P PR P
Sbjct: 1150 LQGLPGPPGPNGEQGSAGIPG-PFGPRGP 1177
Score = 77.0 bits (188), Expect = 3e-13
Identities = 256/1071 (23%), Positives = 312/1071 (29%), Gaps = 257/1071 (23%)
Query: 505 PFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG 564
P PAG P GSQG G G P + P + G P PGA
Sbjct: 131 PGPAGPP----GSQGPRGERGPKGRPGPRGPQGIDGEPGVPG--------QPGAP----- 173
Query: 565 VAQPQVSPHGTPSLPPP----RVVGASPSESPLPSPATNTAGSTCSSLSPMS-------- 612
P G PS P P R A + S + G S+ P+
Sbjct: 174 ------GPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQ 227
Query: 613 -----SSPANPSSEESQLPGPLGPSAFFHP---PTHPQETGSPFPSPEPPH--------- 655
+ P P E PGP+GP P P P E G P + P
Sbjct: 228 GQQGGAGPTGPPGEPGD-PGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGA 286
Query: 656 -------SLPTHYQPEPAKAFPFPADGLGAEGAFQCLEET-PFPHEGP--------EVGR 699
LP K P +GA G+ T P GP E GR
Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346
Query: 700 GGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLAR 759
G QG AP H + L + S + G AR
Sbjct: 347 LGPQG---APGQRGAHGMPGKPGPMGPLGI--------PGSSGFPGNPGMKGEAGPTGAR 395
Query: 760 AKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPS 819
+G Q G G P P +P +P G + T G + G P P
Sbjct: 396 GPEGPQGQRGETGPPGPVGSPGLP-----GAIGTDGTPGAKGPTGSPGTSGP------PG 444
Query: 820 LAATP-FPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRG 878
A P P P + G+ Q +P + F E +GP+G
Sbjct: 445 SAGPPGSPGPQGSTGPQ--------------GIRGQPGDPGVPG-----FKGE--AGPKG 483
Query: 879 PSSGHPLKSKAGVT-PESKAPPPLPAATPDPQTPRPGDRGCPA-RGRPKTRSLGLAPTEA 936
H ++ G E K P T P P G+RG P RG P + L
Sbjct: 484 EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP-VGERGAPGNRGFPGSDGL------- 535
Query: 937 DAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPP---PR 993
+G Q RG + S G G G GL R GL P P
Sbjct: 536 -PGPKGAQGERGP--------VGSSGPKGSQGDPGRPGEPGLPGAR--GLTGNPGVQGPE 584
Query: 994 PRRPRTQAPGSRADPAPR-------VPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAW 1046
+ APG P P P + LP SS P + GA
Sbjct: 585 GKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAP 644
Query: 1047 GKELILKIVQQKNRLREYDFASESEEDEQPPPRG----PGFRGRRGRGEKRKEVELTQGP 1102
GK+ V + A E E P P G PG G G G K + + P
Sbjct: 645 GKD---GEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDP 701
Query: 1103 REDEPQKPR-----KAARQEAGGDGAPAN--------PEEPGGSRPGPGRSPQARGP--- 1146
P PR R E G G P P+ P GS PGP +P GP
Sbjct: 702 GAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGS-PGPSGTPGDTGPPGL 760
Query: 1147 -----SRSL--------------ETGAAAREGGPKCADRPS-VAPKDPLQVPTNTETSEE 1186
R + E GA G P + P P PT +
Sbjct: 761 QGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG-PTGEKGEPG 819
Query: 1187 TRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMG--ASPGLLIPEQPPPSR 1244
R + P P + E+ P AG G PG+ P +
Sbjct: 820 PRGLVGPPGSRGNPGSRGENGPTGA----------VGFAGPQGPDGQPGVKGEPGEPGQK 869
Query: 1245 HDTGTPKPSGSLANTAPHGSSPTPGV---GSLLGGPGGTQAPVSHNSKDPPARQPGEFLA 1301
D G+P P G + PHG + PG+ G PG T P S PP
Sbjct: 870 GDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPP--------G 921
Query: 1302 PVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKD 1361
P P PAG PLG P + P P S +G +
Sbjct: 922 PAGAPG--------------------PAG----PLGEPGKEGPPGLRGDPGSHGRVGDRG 957
Query: 1362 LAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRA-ASPP 1420
AG PP GED +P P PPG A T R P
Sbjct: 958 PAG---------------PPGGPGDKGDPGEDG---QPG-PDGPPGPAGTTGQRGIVGMP 998
Query: 1421 TLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYP 1471
P LP P G A D G P PP P P P
Sbjct: 999 GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPP-GPVGPPGSNGPVGEPGP 1048
Score = 75.5 bits (184), Expect = 1e-12
Identities = 212/840 (25%), Positives = 275/840 (32%), Gaps = 190/840 (22%)
Query: 3 GER-PRGAPPPTMTGDLQ-----PRQVASS--PGHPSQP-PLEDNTPATRTTKGAREAGG 53
GER P+G P P + P Q + PGHPS P P + P + G E G
Sbjct: 144 GERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSG 203
Query: 54 QAQAMEL------------PEA-QPRQARDGELKPPSLRGQ-APSSTPGKRGSPQTPPGR 99
+ L P+ Q +Q G PP G P G RG P+ PPG+
Sbjct: 204 LGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRG-PEGPPGK 262
Query: 100 SPLQA-PSRLAGRAE----GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQ 154
P R E GSP R G + P L + LE + EV P
Sbjct: 263 PGEDGEPGRNGNPGEVGFAGSPGAR---GFPGAPGLPGLKGHRGHKGLEGPK-GEVGAPG 318
Query: 155 GPGTGAPLRP----------GLP----RTEAQPAAEELGFHRCFQEP------------- 187
G P P G+P R Q A + G H +P
Sbjct: 319 SKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSG 378
Query: 188 -PSSFTSTNYTSPSATPRPPAP-------GPPQSRGTSPLQPGSYPEYQASGADSWPPAA 239
P + P+ P P GPP G SP PG A G D P A
Sbjct: 379 FPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVG-SPGLPG------AIGTDGTPGAK 431
Query: 240 ENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTN 299
+ G P + P G + P+G+ Q P + G + P G
Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQ 491
Query: 300 GPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPG 359
GP+ P E GP T P P+ +G PG NR S L P
Sbjct: 492 GPI---------GPPGEEGKRGPRGDPGTVGPPGPVG-ERGAPG--NRGFPGSDGLPGPK 539
Query: 360 AAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTS 419
A ER P G ++G P + PG A G+ +
Sbjct: 540 GAQG------------------ERGPVGSSGPKGSQGDPGRPGEPGLPG----ARGLTGN 577
Query: 420 PGPPDTE-----LAAPGP-----PPARLPQLWDPTAAPYPTP------PGGPLAATRSMF 463
PG E L APG PP + P + P P PG P A +
Sbjct: 578 PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGV 637
Query: 464 FNGQPSPGQRLCLPQSAPLPWPQVL----PTARPSPHGMEMLSRLPFP---AGGPEWQG- 515
+ +PG+ + S P+ P + P P G + L P P G P QG
Sbjct: 638 PGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGV 697
Query: 516 ----GSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571
G+ G LG G+ P E+ + G + +G P P
Sbjct: 698 PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP----------G 747
Query: 572 PHGTPSLPPPRVVGASPSESPL---PSP-----------ATNTAGSTCSSLSP---MSSS 614
P GTP P + P E + P P A TAG+ + P
Sbjct: 748 PSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807
Query: 615 PANPSSEESQLPGP---LGPSAFFHPPTHPQETGSP----FPSPEPPHSLPTHYQPEPAK 667
PA P+ E+ + PGP +GP P E G F P+ P P + EP +
Sbjct: 808 PAGPTGEKGE-PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQP-GVKGEPGE 865
Query: 668 AFPFPADGLGAEGAFQCLEETPFPH-----EGPEVGRG-----GLQGFP----RAPPPYP 713
P G+ G Q L +P PH G + GRG G GFP R PP P
Sbjct: 866 --PGQKGDAGSPGP-QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGP 922
Score = 74.7 bits (182), Expect = 2e-12
Identities = 186/734 (25%), Positives = 227/734 (30%), Gaps = 141/734 (19%)
Query: 2 PGERPRGAPPPTMTGDLQPRQVA-----SSPGHPSQPPLEDNT--PATRTTKGAREAGGQ 54
PGE R PP ++ QP + S G P +P N P R G G
Sbjct: 593 PGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGP 652
Query: 55 AQAMELPEAQPRQARDGELKPPSLRG-QAPSSTPGKRGSP--QTPPGRSPLQAPSRLAGR 111
+ + P + G P +G P PG+ G P Q PG P L R
Sbjct: 653 SGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGP--LGPR 710
Query: 112 AEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQG-PG-TGAPLRPGLPRT 169
E P R +P + P + P D P+G PG +G P G P
Sbjct: 711 GERGNP--------GERGEPGITGLPGEKGMAGGHGP--DGPKGSPGPSGTPGDTGPPGL 760
Query: 170 EAQPAAEEL-------GFHRCFQEPPSSFTSTN-----YTSPSATPRPPAP--------- 208
+ P + G E + T+ N P P P P
Sbjct: 761 QGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGP 820
Query: 209 ----GPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRP 264
GPP SRG PGS E +GA + A P GV EP KG
Sbjct: 821 RGLVGPPGSRGN----PGSRGENGPTGAVGF---AGPQGPDGQPGVKGEPGEPGQKGDAG 873
Query: 265 GGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAY 324
P+G++ P HG + P G G F + P A GPA
Sbjct: 874 SPGPQGLAGS---PGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG 930
Query: 325 PLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERP 384
PL +P P +G PG R D G PG P D P+ P
Sbjct: 931 PLG-EPGKEGPPGLRGDPGSHGRVGD-RGPAGPPGGPGDKGDPGEDGQPG------PDGP 982
Query: 385 PSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPG-PPPARLPQLWDP 443
P GP + QR G+ PG E PG P PA P P
Sbjct: 983 P----------GPAGTTGQR----------GIVGMPGQRG-ERGMPGLPGPAGTPGKVGP 1021
Query: 444 TAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSR 503
T A P GP+ S G+P P P R G
Sbjct: 1022 TGATGDKGPPGPVGPPGSNGPVGEPGPEG----------PAGNDGTPGRDGAVGERGDRG 1071
Query: 504 LPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFF 563
P PAG P GSQGA GT G P + + Q G P G P +
Sbjct: 1072 DPGPAGLP----GSQGAPGTPGPVGAPGD------AGQRGDPG---SRGPIGPPGRAGKR 1118
Query: 564 GVAQPQ-----VSPHGTPSLPPPRVVGASPSESPLPS-PATNTAGSTCSSLSPMS----S 613
G+ PQ HG + LP P N + P
Sbjct: 1119 GLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPP 1178
Query: 614 SPANPSSEESQLPGPLGP---------SAFFHPPTHPQETGSPFPSPEPPH------SLP 658
P PS +E PGPLGP P P E G P P P H +
Sbjct: 1179 GPVGPSGKEGN-PGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIM 1237
Query: 659 THY---QPEPAKAF 669
HY P+P F
Sbjct: 1238 GHYDESMPDPLPEF 1251
Score = 72.4 bits (176), Expect = 8e-12
Identities = 317/1329 (23%), Positives = 405/1329 (30%), Gaps = 294/1329 (22%)
Query: 204 RPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVP--PAEPEPIPKG 261
RP GPP S+G P + P G GVP P P P
Sbjct: 130 RPGPAGPPGSQG---------PRGERGPKGRPGPRGPQGIDGEP-GVPGQPGAPGPPGHP 179
Query: 262 SRPGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTG 321
S PG P G+S +PF A +AG +G G P G
Sbjct: 180 SHPG--PDGLS-------------RPFSAQMAGLDEKSG-----LGSQVGLMPGSVGPVG 219
Query: 322 PAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILP 381
P P Q GQ GG +G PG P P + P
Sbjct: 220 PRGPQGLQ----------GQQGG-------AGPTGPPGEPGD-PGPMGPIGSRG-----P 256
Query: 382 ERPPS--AQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDT-------------- 425
E PP +DG G P + PG A G +PG P
Sbjct: 257 EGPPGKPGEDGEPGRNGNPGEVGFAGSPG----ARGFPGAPGLPGLKGHRGHKGLEGPKG 312
Query: 426 ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWP 485
E+ APG + P GP+ A + G P RL PQ AP
Sbjct: 313 EVGAPG--------------SKGEAGPTGPMGAMGPLGPRGMPGERGRLG-PQGAP---- 353
Query: 486 QVLPTARPSPHGMEMLSRLPFPAGGPEWQG--GSQGALGTAGKTPGPREKLPAVRSSQGG 543
+ HGM P G P G G+ G G AG T + P + + G
Sbjct: 354 -----GQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408
Query: 544 SPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGS 603
P G+ G P SP GT P A P SP P +T G
Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSP-GTSGPPG----SAGPPGSPGPQGSTGPQG- 462
Query: 604 TCSSLSPMSSSPANPSSEESQLP-GPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQ 662
+ P P + P G GP P P E G P +P P
Sbjct: 463 ----IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV 518
Query: 663 PEPA----KAFPFPADGL----GAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP--PPY 712
E + FP +DGL GA+G E P GP+ G QG P P P
Sbjct: 519 GERGAPGNRGFP-GSDGLPGPKGAQG-----ERGPVGSSGPK----GSQGDPGRPGEPGL 568
Query: 713 PTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPG 772
P + + + L G L A +DG PG G
Sbjct: 569 PGARGLTGNPGVQGPEGKL----------------------GPLGAPGEDGRPGPPGSIG 606
Query: 773 LPSPPAAPRVP----ADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLP 828
+ P + +P + G A + G A GKD + PS P L
Sbjct: 607 IRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVG----PSGPVGPPGLA 662
Query: 829 ASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSK 888
+ G + P D A P GPRG + +
Sbjct: 663 GERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGA-VGPLGPRGERGNPGERGE 721
Query: 889 AGVT--PESKAP-----PPLPAATPDPQTPRPGDRGCPA-RGRPKTRSLGLAPTEADAPS 940
G+T P K P P +P P + PGD G P +G P R G+A T
Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGP-SGTPGDTGPPGLQGMPGER--GIAGTPGPKGD 778
Query: 941 QGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRA--SGLRPRRNDG-LGERPPPRPRR- 996
+G +G AEG+ G R L P G GE+ P PR
Sbjct: 779 RGGIGEKG---------------AEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGL 823
Query: 997 ---PRTQA-PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELIL 1052
P ++ PGSR + P A P+ + P + +K A G+ G + +
Sbjct: 824 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDA--GSPGPQGLA 881
Query: 1053 KIVQQKNRLREYDFASESEEDEQPPPRGP----GFRGRRGRGEKRKEVELTQGP--REDE 1106
P P GP G +G RG TQGP
Sbjct: 882 G---------------------SPGPHGPNGVPGLKGGRG----------TQGPPGATGF 910
Query: 1107 PQKPRKAARQEAGGDGAPANP-EEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCAD 1165
P + G PA P EPG P PG R + G A GGP
Sbjct: 911 PGSAGRVGPPGPAGAPGPAGPLGEPGKEGP-PGLRGDPGSHGRVGDRGPAGPPGGPGDKG 969
Query: 1166 RPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACA 1225
P + P + R + P + E P T + P
Sbjct: 970 DPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPG----KVGPTGAT 1025
Query: 1226 GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVS 1285
G+ G PG P PP S G P P G P G+ TPG +G G P
Sbjct: 1026 GDKGP-PG---PVGPPGSNGPVGEPGPEG------PAGNDGTPGRDGAVGERGDRGDP-- 1073
Query: 1286 HNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVP--VAKK 1343
PA PG AP P P + DP +R P+G P K+
Sbjct: 1074 -----GPAGLPGSQGAP-GTPGPVGAPGDAGQRG-------DPG--SRGPIGPPGRAGKR 1118
Query: 1344 GPQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPR 1403
G P + G G ++ H + P + G AG P PR
Sbjct: 1119 GLPGPQGPRGD--KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQG-SAGIPGPFGPR 1175
Query: 1404 SPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPP-LYGSLSANRDSGLPFACADPPQK 1462
PPG G+ +P P+ PP + GS+ G PP +
Sbjct: 1176 GPPGPVGPS-GKEGNPG-----------PLGPIGPPGVRGSVGEAGPEG-------PPGE 1216
Query: 1463 TVPSDPPYP 1471
P PP P
Sbjct: 1217 PGPPGPPGP 1225
Score = 59.7 bits (143), Expect = 6e-08
Identities = 117/455 (25%), Positives = 154/455 (33%), Gaps = 95/455 (20%)
Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488
G PG K + + P + +PG PG+D EV
Sbjct: 615 GLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKD-----------------------GEVG 651
Query: 3489 PSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGALE 3548
PS G P + +G P+ Q P P P G G
Sbjct: 652 PSGPVGPPGLAGERGE------QGPPGPTGFQGLPGPPGPP-------GEGG-------- 690
Query: 3549 RPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPD 3608
+P ++ PG PG + PLG PR G RG G+R PG G
Sbjct: 691 KPGDQGVPGDPGAV----GPLG---PR-GERGN-----------PGERGEPGITG----- 726
Query: 3609 HFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSA---TKPAGCQSSSKDRSAASTPS-KA 3664
L EK ++ H GP+G+ T P G Q +R A TP K
Sbjct: 727 -------LPGEKGMAGGH--GPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKG 777
Query: 3665 LKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTG-GGSQPQ 3723
+ + + A G+ A + ARG P P GP+ + G P P G GS+
Sbjct: 778 DRGGIGEKGAEGT-AGNDGARGLPG---PLGPPGPAGPTGE-KGEPGPRGLVGPPGSRGN 832
Query: 3724 PAS-GQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPRE---AGEQGPHGSLG- 3778
P S G+ A A P P P + P K P AG GPHG G
Sbjct: 833 PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGV 892
Query: 3779 PKEKGESSTKRKKGQVPGPARSESVGSFGRAPS-APDKPPRTPRKQATPS-RVLP-TKPK 3835
P KG T+ G P + VG G A + P P P K+ P R P + +
Sbjct: 893 PGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGR 952
Query: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQG 3870
+ PP K +PG + G P G
Sbjct: 953 VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAG 987
Score = 59.3 bits (142), Expect = 7e-08
Identities = 134/534 (25%), Positives = 171/534 (32%), Gaps = 125/534 (23%)
Query: 3414 RGGRQPFAFRG-VRRPGAPGQKA-RALEGTL--PSKRRRVAMPGSAPGPGEDR-PPPRGS 3468
+G P +G + PG G++ R GT+ P PG+ PG D P P+G+
Sbjct: 482 KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGA 541
Query: 3469 S----PILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPP 3524
P+ S G P ++G P RP +P RG Q P
Sbjct: 542 QGERGPVGSSG-------------PKGSQGDPG---RPGEPGLPGARGLTGNPGVQG-PE 584
Query: 3525 PSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRP-GARGQDA 3583
L P A DGR PG PG + + P LP P G+ G
Sbjct: 585 GKLGPLGAPGEDGR-----------------PGPPGSIGIRGQPGSMGLPGPKGSSGDPG 627
Query: 3584 E-GKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSA 3642
+ G+ G+R APG G P L E+ +G P T +G
Sbjct: 628 KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERG-------EQGPPGPTGFQGLP 680
Query: 3643 TKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELA----------RGTENGMK 3692
P K P+ PR G+ PGE +G G
Sbjct: 681 GPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGN--PGERGEPGITGLPGEKGMAGGHG 738
Query: 3693 PATPKAKPGPSS----------QGSGSPR-----PGTK-TGGGSQPQPASGQLQSETA-- 3734
P PK PGPS QG R PG K GG + A G ++ A
Sbjct: 739 PDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARG 798
Query: 3735 -------TTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLG--------- 3778
PA P+ P P L ++ P GE GP G++G
Sbjct: 799 LPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG---NPGSRGENGPTGAVGFAGPQGPDG 855
Query: 3779 -PKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPD------------KPPRTPRKQAT 3825
P KGE +KG P GS G P P+ PP +
Sbjct: 856 QPGVKGEPGEPGQKGDAGSPGPQGLAGSPG--PHGPNGVPGLKGGRGTQGPPGATGFPGS 913
Query: 3826 PSRVLPTKPKPNSQNKPRPPPSEQRK-------AEPGHTQRKDRLGKAFPQGRP 3872
RV P P P P P E K +PG R G A P G P
Sbjct: 914 AGRVGP--PGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGP 965
Score = 55.1 bits (131), Expect = 1e-06
Identities = 209/874 (23%), Positives = 265/874 (30%), Gaps = 175/874 (20%)
Query: 2050 GSEGRTPERASS--PGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDP 2107
GS+G ER PG P G+ P G A P P +H P D
Sbjct: 138 GSQGPRGERGPKGRPGPRGPQGIDGEPGVP--GQPGAPGP-PGHPSH--------PGPDG 186
Query: 2108 LTSPSRAQ-------GGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTG 2160
L+ P AQ GLG Q+ P P GP+ G Q
Sbjct: 187 LSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPR----------------GPQGLQGQQ 230
Query: 2161 AEDSPVAPPSLTTSPCDPKEALAGCLLQGE-GSPLEDPS---SWPPGSVSAVTCTHSGDT 2216
P PP P P + +G G P ED + PG V +
Sbjct: 231 GGAGPTGPPGEPGDP-GPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGF 289
Query: 2217 PKDSTLRIPEDSRKEKLWESP-GRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGL 2275
P L + R K E P G +P G P+ + A G P G + GR
Sbjct: 290 PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLG-PRGMPGERGRLG 348
Query: 2276 PGPDPQSRGAPPHTNPDRM-PRGH-----SSYSPSNTARLGHREGQAVTAVPTEPPTLQG 2329
P P RGA H P + P G SS P N G G P P +G
Sbjct: 349 PQGAPGQRGA--HGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA-GPTGARGPEGPQGQRG 405
Query: 2330 -AGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTAS 2388
GP P G G + TG G + P P G +T P
Sbjct: 406 ETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465
Query: 2389 DFQSDSPQSHRNASHQTPQGDPLGPQDLK--------QRSRGYKKKPASTENGQWKGQAP 2440
Q P P+G+P GP ++ + RG + P + P
Sbjct: 466 --QPGDPGVPGFKGEAGPKGEP-GPHGIQGPIGPPGEEGKRGPRGDPGTV--------GP 514
Query: 2441 HGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRK 2500
GPV R PG +R PG+ P P AQ P+
Sbjct: 515 PGPV-------GERGAPG--------NRGFPGSDGLPGPKG--AQGERGPV--------- 548
Query: 2501 KSHRVSGKERPNHSRGDPSHVTQP-----------PPAQGSKEVLRAPGSPHSQQLHPPS 2549
G P S+GDP +P P QG + L G+P P
Sbjct: 549 ------GSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP 602
Query: 2550 PTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGK 2609
+ P P + D P +A R P D G
Sbjct: 603 GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG-- 660
Query: 2610 LRGRRLREESILPVSADVISD-----GRGSRPSPAMASY---AASPSHCLSVEGGPEADG 2661
L G R + P + G G +P A P G P G
Sbjct: 661 LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG 720
Query: 2662 EQPPRLATL----------GPGVMEGAAETDQEALCAGETGAQKPPGDRMLC--PG-RMD 2708
E P + L GP +G+ G G Q PG+R + PG + D
Sbjct: 721 E--PGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD 778
Query: 2709 GAALGEQPTGQKGAS----ARGFWGPRETKALGVCKESG--SEPAEDSSRA-----HSRS 2757
+GE+ G +G + ARG GP LG +G E E R SR
Sbjct: 779 RGGIGEK--GAEGTAGNDGARGLPGP-----LGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831
Query: 2758 EEGVWEENTP--------PLGPLGFPETSSSPAD-----STTSSCLQGLPDNPDTQGGVQ 2804
G EN P P GP G P P + S QGL +P G
Sbjct: 832 NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSP----GPH 887
Query: 2805 GPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPG 2838
GP G G + PP S ++ PPG
Sbjct: 888 GPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921
Score = 53.9 bits (128), Expect = 3e-06
Identities = 104/439 (23%), Positives = 139/439 (31%), Gaps = 49/439 (11%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPP-PRGSSPILSEGSLPALLHLCSE 3486
PG PG K L + V PGS GE P P G+ L +P
Sbjct: 293 PGLPGLKGHRGHKGLEGPKGEVGAPGS---KGEAGPTGPMGAMGPLGPRGMPG------- 342
Query: 3487 VAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCALDGA 3546
+G P H + G P P S P + G G
Sbjct: 343 -----ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397
Query: 3547 LERPENEASPGSPGPLLQQALP--LGASLPRPGARG-QDAEGKRAPLVFSGKRRAPGARG 3603
G PGP+ LP +G PGA+G + G P +G +PG +G
Sbjct: 398 EGPQGQRGETGPPGPVGSPGLPGAIGTD-GTPGAKGPTGSPGTSGPPGSAGPPGSPGPQG 456
Query: 3604 RCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSK 3663
P + + + E GP+G P G R P
Sbjct: 457 STGPQGIR-----GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG- 510
Query: 3664 ALKFPVHPRKAVGSL-APGELARGTENGMK-PATPKAKPGPSSQGSGSPRPGTKTGGGSQ 3721
V P VG APG +G+ P + + GP GS P+ G++ G
Sbjct: 511 ----TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP--VGSSGPK-GSQGDPGRP 563
Query: 3722 PQP----ASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSL 3777
+P A G + P P +P + P + P G GP GS
Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623
Query: 3778 G-PKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKP 3836
G P + GE+ GQ P + VG PS P PP ++ PT
Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVG-----PSGPVGPPGLAGERGEQGPPGPT---- 674
Query: 3837 NSQNKPRPPPSEQRKAEPG 3855
Q P PP +PG
Sbjct: 675 GFQGLPGPPGPPGEGGKPG 693
Score = 53.9 bits (128), Expect = 3e-06
Identities = 137/539 (25%), Positives = 171/539 (31%), Gaps = 124/539 (23%)
Query: 873 PSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLA 932
P GP GP AG T E P P P PG RG T ++G A
Sbjct: 802 PLGPPGP---------AGPTGEKGEPGPRGLVGPPGSRGNPGSRG----ENGPTGAVGFA 848
Query: 933 PTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP 992
+ G + G+ + + D S G +GS G +G+ P G G + PP
Sbjct: 849 GPQGPDGQPGVKGEPGEPGQ--KGDAGSPGPQGLAGSPGPHGPNGV-PGLKGGRGTQGPP 905
Query: 993 RPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPP--RKDPRKRKARG------- 1043
T PGS P P A P + PP R DP G
Sbjct: 906 GA----TGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGP 961
Query: 1044 -GAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGP----GFRGRRG-------RGE 1091
G G + + ED QP P GP G G+RG RGE
Sbjct: 962 PGGPGDK------------------GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGE 1003
Query: 1092 KRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLE 1151
+ + GP P K A GD P P P GS GP P GP+ +
Sbjct: 1004 RG--MPGLPGPAGT----PGKVGPTGATGDKGPPGPVGPPGSN-GPVGEPGPEGPAGNDG 1056
Query: 1152 T----GAAAREG-----GPKCADRPSVAPKDPLQVPTNTETSEETRPS------------ 1190
T GA G GP AP P V + + P
Sbjct: 1057 TPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116
Query: 1191 ---LDFPQ-----EAKEPETAEESAPDSTEFT--EALRSPPAACAGEMGAS--PGLLIPE 1238
L PQ + + + FT + L PP GE G++ PG P
Sbjct: 1117 KRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP-NGEQGSAGIPGPFGPR 1175
Query: 1239 QPP----PSRHD--------TGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP--- 1283
PP PS + G P GS+ P G PG G PG A
Sbjct: 1176 GPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGD 1235
Query: 1284 -VSHNSKDPPARQPGEFLAPVANPSSTACPKPSV------LSSKISSFGCDPAGFNRDP 1335
+ H + P P EF A P P V LSS+I + P G + P
Sbjct: 1236 IMGHYDESMPDPLP-EFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMR-SPDGSKKHP 1292
Score = 52.0 bits (123), Expect = 1e-05
Identities = 290/1238 (23%), Positives = 372/1238 (30%), Gaps = 243/1238 (19%)
Query: 1082 GFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSP 1141
G RGR G +QGPR + K R R G DG P P +PG PGP P
Sbjct: 126 GIRGRPGPAGPPG----SQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGA--PGPPGHP 179
Query: 1142 QARGP---SRSLET-------------------------------GAAAREGGPKCADRP 1167
GP SR G ++GG P
Sbjct: 180 SHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPP 239
Query: 1168 SVAPKDPLQVPTNTETSEETRPSLDFPQEAKEP-------ETAEESAPDSTEFTEALRSP 1220
P DP + E P P E EP E +P + F A P
Sbjct: 240 G-EPGDPGPMGPIGSRGPEGPPGK--PGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP 296
Query: 1221 PAACAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGT 1280
G G GL P+ + G P+G + P G PG LG G
Sbjct: 297 --GLKGHRG-HKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQG-- 351
Query: 1281 QAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPV 1340
AP + P + PG + P+ P S+ P + + G R P G P
Sbjct: 352 -APGQRGAHGMPGK-PGP-MGPLGIPGSSGFPGNPGMKGEAGPTGA------RGPEG-PQ 401
Query: 1341 AKKG----PQPYSSPHSELFLGPKDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGS 1396
++G P P SP +G G P S PP S+ G GS
Sbjct: 402 GQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTS---GPPGSAGPPGSPGPQ-GS 457
Query: 1397 LEPQLPRSPPGT-----------AETEPG-----RAASPPTLESSSLFPDLPVDRFDPPL 1440
PQ R PG + EPG PP E P P
Sbjct: 458 TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP 517
Query: 1441 YGSLSANRDSGLPFACADPPQKTVPSD--PPYPSFLLLEEVSPMLPSHFPDLSGGKVLS- 1497
G A + G P + P K + P S + P P P L G + L+
Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGE-PGLPGARGLTG 576
Query: 1498 --KTCPPERTVVPGAAPSLPGK-GSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTR 1554
PE + P AP G+ G S+ + L K +
Sbjct: 577 NPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPG-------------SMGLPGPKGSS 623
Query: 1555 GAPRELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAES 1614
G P + EA + G P QR P +D VG E E
Sbjct: 624 GDPGKPGEAGNAG---------VPGQR-----GAPGKDG-EVGPSGPVGPPGLAGERGEQ 668
Query: 1615 AVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFHFQPVQKAGA 1674
QG PG P PG + D + P PRG + P ++
Sbjct: 669 GPPGPTGFQGLPGPPGPPGEGGKPGDQGV----PGDPGAVGPLGPRGERGN--PGERGEP 722
Query: 1675 SKTGL---------------------CQAEGDSRPPQDVCLPEP---SKQPGPQLDAGSL 1710
TGL GD+ PP +P + PGP+ D G +
Sbjct: 723 GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI 782
Query: 1711 AKCSPDQELSFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQP-HRGAPAPEAF- 1768
++ A D R LP G L PG A +G P P
Sbjct: 783 -------------GEKGAEGTAGNDGARGLP-----GPLGPPGPAGPTGEKGEPGPRGLV 824
Query: 1769 GSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNE 1828
G P P +G+ P GA QG G+ G P G PG +G+
Sbjct: 825 GPPGSRGNP--GSRGENGPT-------GAVGFAGPQGPD-GQPGVKGEP--GEPGQKGDA 872
Query: 1829 FAPA--GASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDP----ALSPPIRQLQLPGP 1882
+P G + P G P V R +Q P ++ PGP
Sbjct: 873 GSPGPQGLAGSPGPHG----------PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGP 922
Query: 1883 GVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAV 1942
A G LG P + P GL G G+V G PGG P
Sbjct: 923 AGAPGPAGPLG---------EPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGE 973
Query: 1943 AGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVS--PGGTDNHASVNASPKTALTG 2000
G DG G G + G Q + E G+ PG V + T G
Sbjct: 974 DGQP---GPDGPPGPAGTTGQRGIVGMPGQ-RGERGMPGLPGPAGTPGKVGPTGATGDKG 1029
Query: 2001 PTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERAS 2060
P G V GS + P + +P R+ A+ G G P
Sbjct: 1030 P-PGPV---GPPGSNGPVGEPGPEGPAGNDGTPGRDG-AVGERGDRGDPGPAG-LPGSQG 1083
Query: 2061 SPGLNKPLLATGDSPAPSVGDLAACAP-SPTSAAHMPCSLGPL-PREDPLTSPSRAQGGL 2118
+PG P+ A GD A GD + P P A GP PR D R G
Sbjct: 1084 APGTPGPVGAPGD--AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQ 1141
Query: 2119 GGQ--LPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDS-----PVAPPSL 2171
G PPGP + P +G E + P+ PP +
Sbjct: 1142 KGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGV 1201
Query: 2172 TTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVT 2209
S + AG EG P E PPG +T
Sbjct: 1202 RGSVGE-----AG----PEGPPGEPGPPGPPGPPGHLT 1230
Score = 44.3 bits (103), Expect = 0.002
Identities = 98/382 (25%), Positives = 121/382 (31%), Gaps = 76/382 (19%)
Query: 3504 DPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCAL----DGALERPENEASPGSP 3559
DPVT P C + S + P + F +G+ L G RP PGS
Sbjct: 84 DPVTPPGECCPVCS---QTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQ 140
Query: 3560 GPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKE 3619
GP ++ P G RPG RG P G+ PG G P
Sbjct: 141 GPRGERG-PKG----RPGPRG--------PQGIDGEPGVPGQPGAPGPPGHP-------- 179
Query: 3620 KEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLA 3679
S GP G SA + S P PV PR G
Sbjct: 180 ---------SHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSV--GPVGPRGPQG--- 225
Query: 3680 PGELARGTENGMKPATPKAKPG-PSSQG----SGSPRPGTKTGGGSQPQPASGQLQSETA 3734
+G + G P P +PG P G G P K G +P + A
Sbjct: 226 ----LQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFA 281
Query: 3735 TTPAKPSFPSRSPAPERLPARAQAKSCTKGPR-EAGEQGPHGSLG-PKEKGESSTKRKKG 3792
+P FP P KG R G +GP G +G P KGE+ G
Sbjct: 282 GSPGARGFPGAPGLPG-----------LKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMG 330
Query: 3793 QVPGPARSESV-GSFGRAPSAPDKPPRTPRKQATPSRVLPTKPK--PNSQNKPRPPPSEQ 3849
+ GP + G GR P P P + P P P S P P
Sbjct: 331 AM-GPLGPRGMPGERGRL--GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP---G 384
Query: 3850 RKAEPGHTQRKDRLGKAFPQGR 3871
K E G T + G PQG+
Sbjct: 385 MKGEAGPTGAR---GPEGPQGQ 403
Score = 39.3 bits (90), Expect = 0.078
Identities = 94/391 (24%), Positives = 126/391 (32%), Gaps = 75/391 (19%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDR--------PPPRGSSPILSEGSLPA 3479
PG PG K E P P PGP P RG + LP
Sbjct: 962 PGGPGDKGDPGEDGQPG-------PDGPPGPAGTTGQRGIVGMPGQRGERGM---PGLPG 1011
Query: 3480 LLHLCSEVAPSTT---KGWPETLERPVD--PVTHPIRGCELPSNHQECPPPSLSPFPAAL 3534
+V P+ KG P + P PV P G E P+ + P
Sbjct: 1012 PAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEP--GPEGPAGNDGTPGRD------GA 1063
Query: 3535 ADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAE-GKRAPL--- 3590
RGD G P ++ +PG+PG P+GA PG GQ + G R P+
Sbjct: 1064 VGERGDRGDPGPAGLPGSQGAPGTPG-------PVGA----PGDAGQRGDPGSRGPIGPP 1112
Query: 3591 VFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQS 3650
+GKR PG +G P + DH + ++ + G RG P G
Sbjct: 1113 GRAGKRGLPGPQG---PRGDKGDHGDRGDR--------GQKGHRGFTGLQGLPGPPG--- 1158
Query: 3651 SSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPKAKPG-PSSQGSGS 3709
+ ++ +A P P PR G + P G E P P PG S G
Sbjct: 1159 PNGEQGSAGIPG-----PFGPRGPPGPVGPS----GKEGNPGPLGPIGPPGVRGSVGEAG 1209
Query: 3710 PRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAG 3769
P G P G L + P PE +A K
Sbjct: 1210 PEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNK-----T 1264
Query: 3770 EQGPHGSLGPKEKGESSTKRKKGQVPGPARS 3800
+ G H +L + + G PAR+
Sbjct: 1265 DPGVHATLKSLSSQIETMRSPDGSKKHPART 1295
Score = 38.9 bits (89), Expect = 0.10
Identities = 29/96 (30%), Positives = 35/96 (36%), Gaps = 16/96 (16%)
Query: 3206 PAPKHHRGKRSAGKAAGSPG--DPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSA 3263
P P GK G PG P G GE + +PGER +P P
Sbjct: 683 PGPPGEGGKPGDQGVPGDPGAVGPLGPRGE--RGNPGERGEPGITGLPGEK--------- 731
Query: 3264 SATALADAGSPGPPRTTPSPSPDPWAGGEPLLQATP 3299
+A P P+ +P PS P G P LQ P
Sbjct: 732 ---GMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP 764
Score = 35.8 bits (81), Expect = 0.86
Identities = 71/294 (24%), Positives = 84/294 (28%), Gaps = 41/294 (13%)
Query: 1684 GDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRLLP-- 1741
GD P + P P PGP G + Q E + LP
Sbjct: 966 GDKGDPGEDGQPGPDGPPGPAGTTGQ-------------RGIVGMPGQRGERGMPGLPGP 1012
Query: 1742 CEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSH 1801
G P T D+ G P P P+ DG P D GA
Sbjct: 1013 AGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD-----GAVGER 1067
Query: 1802 AAQGHS--AGRAGGHLHP----TAGRPGFEGNEFAPAGASSLTAP-RGREAWLVPVPSPA 1854
+G AG G P G PG G P + P R + L P
Sbjct: 1068 GDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPR 1127
Query: 1855 CVSNTHPSRRSQDPALSPPIRQLQ-LPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLE 1913
H R + LQ LPGP + G G+ P V PSG E
Sbjct: 1128 GDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKE 1187
Query: 1914 GGT----------VEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEAD--GHW 1955
G V G GP +G PG P GH D GH+
Sbjct: 1188 GNPGPLGPIGPPGVRGSVGEAGP-EGPPGEPGPPGPPGPPGHLTAALGDIMGHY 1240
Score = 35.0 bits (79), Expect = 1.5
Identities = 36/133 (27%), Positives = 46/133 (34%), Gaps = 37/133 (27%)
Query: 3187 PGGLEGSSAVAHLLNSITEPAPKHHRG---KRSAGKAAGS--------------PGDPWG 3229
P GL+G + + P PK RG ++ A AG+ P P G
Sbjct: 757 PPGLQGMPGERGIAGT---PGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTG 813
Query: 3230 QEGEAKKDS----PGERAKPRARST-----------PSNPDG--AATPDSASATALADAG 3272
++GE PG R P +R P PDG + DAG
Sbjct: 814 EKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAG 873
Query: 3273 SPGPPRTTPSPSP 3285
SPGP SP P
Sbjct: 874 SPGPQGLAGSPGP 886
Score = 34.3 bits (77), Expect = 2.5
Identities = 49/193 (25%), Positives = 61/193 (31%), Gaps = 20/193 (10%)
Query: 3692 KPATPKAKPGPSSQG-SGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPE 3750
+P P PS G G RP + G + G S+ P P P+
Sbjct: 169 QPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLG---SQVGLMPGSVG-PVGPRGPQ 224
Query: 3751 RLPARAQAKSCTKGPREAGEQGPHGSLG----------PKEKGESSTKRKKGQVPGPARS 3800
L + T P E G+ GP G +G P E GE G+V G A S
Sbjct: 225 GLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEV-GFAGS 283
Query: 3801 ESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEP-GHTQR 3859
F AP P K + P + P P P G
Sbjct: 284 PGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGE 343
Query: 3860 KDRLGKAFPQGRP 3872
+ RLG PQG P
Sbjct: 344 RGRLG---PQGAP 353
Score = 34.3 bits (77), Expect = 2.5
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 9/74 (12%)
Query: 3206 PAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDS--A 3263
P PK +G+R GS G P G +G+ + PGE P AR NP G P+
Sbjct: 536 PGPKGAQGERGP---VGSSG-PKGSQGDPGR--PGEPGLPGARGLTGNP-GVQGPEGKLG 588
Query: 3264 SATALADAGSPGPP 3277
A + G PGPP
Sbjct: 589 PLGAPGEDGRPGPP 602
Score = 32.7 bits (73), Expect = 7.3
Identities = 67/264 (25%), Positives = 85/264 (32%), Gaps = 62/264 (23%)
Query: 2633 GSRPSPAMASYAASPSHCLSVEGGPEADGEQPPR--LATLGPGVMEGAAETDQEALCAGE 2690
G +P +A SP G P G + R GP GA + EA G
Sbjct: 270 GRNGNPGEVGFAGSPG-ARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGP 328
Query: 2691 TGAQKPPGDRMLCPGRMDGAALGEQPT-GQKGASARGFWG-PRETKALGVCKESG----- 2743
GA P G R + PG + LG Q GQ+GA G G P LG+ SG
Sbjct: 329 MGAMGPLGPRGM-PG--ERGRLGPQGAPGQRGA--HGMPGKPGPMGPLGIPGSSGFPGNP 383
Query: 2744 ---SEPAEDSSRAHS-----RSEEG-------------VWEENTPPL-GPLGFPETSSSP 2781
E +R R E G + + TP GP G P TS P
Sbjct: 384 GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPP 443
Query: 2782 AD-----------STTSSCLQGLPDNPDTQG--------------GVQGPEGPTPDASGS 2816
ST ++G P +P G G+QGP GP +
Sbjct: 444 GSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR 503
Query: 2817 SAKDPPSLFDDEVSFSQLFPPGGR 2840
+ P + PG R
Sbjct: 504 GPRGDPGTVGPPGPVGERGAPGNR 527
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 90.9 bits (224), Expect = 2e-17
Identities = 255/1046 (24%), Positives = 328/1046 (31%), Gaps = 188/1046 (17%)
Query: 1 MPG-ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED--NTPATRTTKGAREAGGQAQA 57
+PG + P+G P T Q + PG P P L P + G + + G
Sbjct: 462 IPGVDGPKGEPGLLCT---QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518
Query: 58 MELPEAQPRQARDGELKPPSLRGQA-----PSSTPGKRGSP--QTPPGRSPLQAPSRLAG 110
LP G+ P L+G+ P G G P + PGR L G
Sbjct: 519 TGLPGFPGFPGAQGD---PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575
Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGP-GTGAPLRPGLPRT 169
+G P + L ++ + P +P P P GP G G PGL T
Sbjct: 576 -VKGLPGPKGELALSGEKGDQGPPGDPGSPGS-----PGPAGPAGPPGYGPQGEPGLQGT 629
Query: 170 EAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQ--PGSYPEY 227
+ P A PP S S TP P PGPP G Q PG
Sbjct: 630 QGVPGAPG---------PPGEAGPRGELSVS-TPVPGPPGPPGPPGHPGPQGPPGIPGSL 679
Query: 228 QASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSR--PGGSPR-GVSFQFPFPALHGA 283
G P P E PG F PP PKG + PG G + P L G
Sbjct: 680 GKCGDPGLPGPDGEPGIPGIGFPGPPG-----PKGDQGFPGTKGSLGCPGKMGEPGLPGK 734
Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQP 342
P A GP F +G E P P LP P L +G P
Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794
Query: 343 GGLNRHSDLSGALSSPGAAHSAPR-----PFSDSLH-------KSLTKILPERPPSAQDG 390
G G PG PR P + L K+ K P P + G
Sbjct: 795 G----QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850
Query: 391 LGSTRGPPS---------SLPQRHFPGQA--------------YRASGVDTSPGPPDT-- 425
G P L QR +PG G PGPP
Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910
Query: 426 ---ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPL 482
+ +PG P + Q P A G P + S + PG L A
Sbjct: 911 TPGQRGSPGIPGVK-GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG----LKGFAGN 965
Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK--------- 533
P + P G++ L LP PAG P G +G LG+ G P +
Sbjct: 966 PGEKG-NRGVPGMPGLKGLKGLPGPAGPP----GPRGDLGSTGNPGEPGLRGIPGSMGNM 1020
Query: 534 -LPAVRSSQG--------GSPALFTYNGMTDPGAQPLFFGVAQP-QVSPHGTPSLPPPRV 583
+P + +G G P L +G+ +P + +P P G P LP
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080
Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSS-PANPSSEESQ----LPGPLGPSAFFHPP 638
+ P P AG + SP S P P + G LGP PP
Sbjct: 1081 KKGEMGQ-PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139
Query: 639 THPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVG 698
P GSP P + P PA G +G L P P P G
Sbjct: 1140 GLPGFPGSPGPMGIRGD--------QGRDGIPGPA---GEKGETGLLRAPPGPRGNP--G 1186
Query: 699 RGGLQGFPRAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLL 756
G +G AP P P ++ A R + + F G +
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAG-------------PRGPTGIEGFPGPPGLPGAI 1233
Query: 757 LA-----RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811
+ R G + SPG PG P PP + + G + H G A G
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293
Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871
L P L P P D + G++ + NP F+
Sbjct: 1294 LGAPGTPGL-----PGPRGDPGF-----------QGFPGVKGEKGNP----GFLGSIGPP 1333
Query: 872 EPSGPRGPSS--GHPLKSKAGVTPESKAPPPLPA-----ATPDPQTPRPGDRG-CPARGR 923
P GP+GP G P K P S PP P P P P PG+ G C RG+
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP-PGNLGPCGPRGK 1392
Query: 924 PKTRSLGLAPTEADAPSQGRQQRRGK 949
P G T A +G + +G+
Sbjct: 1393 PGKD--GKPGTPGPAGEKGNKGSKGE 1416
Score = 86.7 bits (213), Expect = 4e-16
Identities = 353/1494 (23%), Positives = 441/1494 (29%), Gaps = 412/1494 (27%)
Query: 184 FQEPPSSFTSTNYTSPSATPRPPAP----------GPPQSRGTS-----------PLQPG 222
F PP S +T P P P P G RG S P PG
Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPG 112
Query: 223 SYPEYQASGADSWPPA-AENSFPG--ANFGVP--------------PAEPEPIPKGSR-- 263
+ Y G + E FPG G P PA+ E I ++
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172
Query: 264 PG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG-- 319
PG G+P P P G P P G GP P+G E +G
Sbjct: 173 PGLPGAPGPQGLPGP-PGFPGPVGPPGPPGFFGFPGAMGP-----RGPKGHMGERVIGHK 226
Query: 320 --------TGPAYP----LPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAP 365
TGP P + T P +G+ G G G PG ++ +
Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286
Query: 366 R--PFSDSLHKSLTKI-LPERPPSAQDGLGSTRGPPSSLPQRHFPGQ------------- 409
+ P L K +P P S +G+ RG P + + GQ
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGS--EGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344
Query: 410 ----AYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP-YPTPPGGPLAATR---- 460
Y+ G + +PGP PGP AR PQ P+ P P PG R
Sbjct: 345 EYYDTYQEKGDEGTPGP-------PGPRGARGPQ--GPSGPPGVPGSPGSSRPGLRGAPG 395
Query: 461 ------SMFFNGQP------SPGQRLC-----LPQSAPLPWPQ---VLPTARPSPHGME- 499
S G+P +PG C LP S P P V P HG+
Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455
Query: 500 -------------------MLSRLPFPAGGPEWQG-----------GSQGALGTAGKTPG 529
+ ++ P+ G P G G QGA G G
Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515
Query: 530 P-REKLPAVRSSQG--GSPALFTYNGMT-----------DPG--AQPLFFGVAQPQVSPH 573
P LP G G P L G T DPG QP G+ +P
Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP- 574
Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPS 632
G LP P+ A E P G S SP + PA P Q PG G
Sbjct: 575 GVKGLPGPKGELALSGEKGDQGP----PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630
Query: 633 AFFHPPTHPQETG--------SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQC 684
P P E G +P P P P P H P+ P G G
Sbjct: 631 GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---- 686
Query: 685 LEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLA 744
P E G G+ GFP P P F + SL
Sbjct: 687 -----LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG------------------- 721
Query: 745 AFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQ 804
K G PG PGLP P V G T G+
Sbjct: 722 -------------CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG------TPGFPGERG 762
Query: 805 AEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSF 864
G+ + LP L TP E L+G P
Sbjct: 763 NSGEHGEIGLPGLPGLPGTPG-------------------NEGLDGPRGDPGQP------ 797
Query: 865 IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924
P G +GP G ++ G ++ P L Q R G G +G P
Sbjct: 798 -------GPPGEQGP-PGRCIEGPRG----AQGLPGLNGL--KGQQGRRGKTG--PKGDP 841
Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984
L + + S G +G+ L ++ G G L P D
Sbjct: 842 GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR-------------GYPGNPGILGPPGED 888
Query: 985 GL--------GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDP 1036
G+ PP P P T PG R P +P +R P K
Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGT--PGQRGSPG--IPGVKG---------QRGTPGAKGE 935
Query: 1037 RKRKARGGAWGKELILKIVQQKNRLREYDFA-SESEEDEQPPPRGPGFRGRRGRGEKRKE 1095
+ K G G I ++ K FA + E+ + P PG +G +G
Sbjct: 936 QGDK---GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL------ 986
Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155
P P PR G G+ NP EP G R PG P + G
Sbjct: 987 ------PGPAGPPGPR-------GDLGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTL 1032
Query: 1156 AREGGPKCADRPSVAPKDPLQVPTNTE-TSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214
G P A RP + LQ SE TRP P T + P
Sbjct: 1033 ---GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP-------TGDPGLPGD---- 1078
Query: 1215 EALRSPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272
GEMG PG L P P + G+P G PHG G+
Sbjct: 1079 -------MGKKGEMGQPGPPGHLGPAGPEGA---PGSPGSPGLPGKPGPHGDLGFKGIKG 1128
Query: 1273 LLGGPG-----------------GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPS 1315
LLG PG G + + PA + GE A P P
Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP--- 1185
Query: 1316 VLSSKISSFGCDPAGFNRDPLGVP--VAKKGPQPYSSPHS----ELFLGPKDLAGCFLEE 1369
G A +R G P +KG + P E F GP L G +
Sbjct: 1186 ---------GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236
Query: 1370 L---HPKPSARDAP-------PASSSCLCQDGEDAGSLEPQLPRSPPGTAET--EPGRAA 1417
P +R +P P S + G D GS+ P+ PPGTA PGR
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKG-DKGSMGHPGPKGPPGTAGDMGPPGRLG 1295
Query: 1418 SPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLP--FACADPPQKTVPSDPP 1469
+P T P LP R DP G + G P PP P PP
Sbjct: 1296 APGT-------PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342
Score = 77.8 bits (190), Expect = 2e-13
Identities = 289/1237 (23%), Positives = 378/1237 (30%), Gaps = 221/1237 (17%)
Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPIPKGS 262
PGPP + + P + + + D P + PG ++G P
Sbjct: 238 PGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297
Query: 263 RPG-----GSP--RGVSFQFPFPALHGAS-TKPFPADVAGHAFTNGPLVFAFHQPQGAWP 314
+PG G P GV FP L G K D+ F + +Q +G
Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG--- 354
Query: 315 EEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372
+ GP P + PS P G PG + L GA PG S
Sbjct: 355 -DEGTPGPPGPRGARGPQGPSGPPGVPGSPG--SSRPGLRGAPGWPGLKGSKG------- 404
Query: 373 HKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP 432
ER +D +G T G P PG PGPP + GP
Sbjct: 405 ---------ERGRPGKDAMG-TPGSPGCAGSPGLPGSP-------GPPGPPGDIVFRKGP 447
Query: 433 PPAR-LP-QLWDPTAAPYPTPPGGP-LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489
P LP L P P G P L T+ + G P L +P Q
Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507
Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL-----PAVRSSQG-- 542
+ SP G + LP G P QG G G G+T P ++ P +R G
Sbjct: 508 GLKGSP-GSPGNTGLPGFPGFPGAQG-DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565
Query: 543 ---GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH--GTPSLPPPRVVGASPSESPLPSPA 597
G P G+ P + G Q P G+P P P P P P
Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625
Query: 598 TN-TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP--------- 647
T G + P + P S + +PGP GP PP HP G P
Sbjct: 626 LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG---PPGHPGPQGPPGIPGSLGKC 682
Query: 648 ----FPSPEPPHSLPTHYQPEPA-----KAFPFPADGLGAEG------------------ 680
P P+ +P P P + FP LG G
Sbjct: 683 GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742
Query: 681 ----AFQCLEETP-FPHEGPEVGRGGLQGFPRAPP-PYPTHHFSLSSASLD--------Q 726
A TP FP E G G G P P P + L D +
Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802
Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL-----PSPPAAPR 781
C + R L + G R K G + PG PGL P +P
Sbjct: 803 QGPPGRCIEGPRGAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPG 859
Query: 782 VPA-DAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFP-----LPASDLDME 835
+P G L G G+D + P P P P
Sbjct: 860 IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919
Query: 836 DDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT--P 893
T G + NP S V D+ G +G + K GV P
Sbjct: 920 IPGVKGQRGTPGAKGEQGDKGNPG-PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978
Query: 894 ESKAPP--PLPAATPDPQ-----TPRPGDRGCPARGRPKTR-SLGLAPTEADAPSQGRQQ 945
K P PA P P+ T PG+ G RG P + ++G+ ++ + G
Sbjct: 979 GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPG 1036
Query: 946 RRGKQ----LKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQA 1001
R G+ + + D G +EG+ G G P + GL P ++
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG------PTGDPGL---PGDMGKKGEMGQ 1087
Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061
PG P P A S LP + P G G + I K L
Sbjct: 1088 PGPPGHLGPAGPEGAP-----GSPGSPGLPGKPGPH------GDLGFKGI------KGLL 1130
Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR-------GEKRKE--VELTQGPREDEPQKPR 1111
P GP G RG +GR GEK + + GPR + +
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190
Query: 1112 KAARQEAGGDGAP--------ANPEEPGGSR--PGPGRSPQARGPSRSLETGAAAREGGP 1161
K R G G P A P P G PGP P A P ++ G G P
Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250
Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS------TEFTE 1215
AP P ++ + + S+ P P TA + P T
Sbjct: 1251 G-------APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP 1303
Query: 1216 ALRSPPA-----ACAGEMG--------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH 1262
R P GE G PG + P+ PP R D GT K + P
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363
Query: 1263 GSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297
G+ PG+ G GP G P K +PG
Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400
Score = 69.7 bits (169), Expect = 5e-11
Identities = 281/1179 (23%), Positives = 364/1179 (30%), Gaps = 217/1179 (18%)
Query: 65 PRQAR--DGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122
PR AR G PP + G SS PG RG+P P + R A G+P
Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP--- 420
Query: 123 GIASSRTKPTLDETPENP-----------------QLEAAQLPEVDTPQG-PG---TGAP 161
G A S P P P L + +P VD P+G PG T P
Sbjct: 421 GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP 480
Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP 221
PG P P G ++ + SP T P PG P ++G L+
Sbjct: 481 YIPGPPGLPGLPGLH--GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538
Query: 222 GSYPEYQASGADSWP--PAAENSFPGANF-----GVPPAEPEPIPKGSRPGGSPRGVSFQ 274
Q G P P PG G P + P PKG +G Q
Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKG--DQ 595
Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSP 334
P P G+ P PA AG P G P+ G +P P P
Sbjct: 596 GP-PGDPGSPGSPGPAGPAG--------------PPGYGPQGEPGLQGTQGVPGAPGP-- 638
Query: 335 LPCYQGQPGGLNRHSDLSGALSSPG-AAHSAPR---PFSDSLHKSLTKILPERPPSAQDG 390
P G G L+ + + G PG H P+ SL K LP P + G
Sbjct: 639 -PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP--GPDGEPG 695
Query: 391 LGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY 448
+ GPP + FPG G PG ++ PG P P L P
Sbjct: 696 IPGIGFPGPPGPKGDQGFPG----TKGSLGCPG----KMGEPGLPGK--PGLPGAKGEPA 745
Query: 449 PTPPGGPLAATRSMFFNGQPS-PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP 507
PGGP G P PG+R HG L LP
Sbjct: 746 VAMPGGP----------GTPGFPGER-----------------GNSGEHGEIGLPGLPGL 778
Query: 508 AGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGV 565
G P G G G G+ P E+ P R +G G+ L NG+ +
Sbjct: 779 PGTP-GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR------ 831
Query: 566 AQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPS---- 619
+ + P G P +P G S P + + G + P+ P NP
Sbjct: 832 -RGKTGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQ-GEMGPLGQRGYPGNPGILGP 884
Query: 620 -SEESQL-----PGPLGPSAFFHPPTHPQETGSP-FPSPEPPHSLPTHYQPEPAKAFPFP 672
E+ + PG +GP P P + GSP P + P + K P P
Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944
Query: 673 AD-----GLGAEGAFQCLEETPFPHEGPEV----GRGGLQGFP-RAPPPYPTHHFSLSS- 721
++ G E + P V G GL+G P A PP P +
Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004
Query: 722 ----------ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG-- 769
S+ + + + F GL G + PG
Sbjct: 1005 PGEPGLRGIPGSMGNMGM-----PGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059
Query: 770 ---PPGLPSPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPF 825
PG P P P +P D G + G A EG + LP
Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----- 1114
Query: 826 PLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPL 885
P P DL + L L + G P P G RG +
Sbjct: 1115 PGPHGDLGFKGIKGL--LGPPGIRGPPGLPGFP----------GSPGPMGIRGDQGRDGI 1162
Query: 886 KSKAGVTPES--KAPPPLPAATPDPQTPRPGDRGCPA-RGRP-KTRSLGLAPTEADAPSQ 941
AG E+ PP P P Q + GDRG P G P + ++G A +
Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221
Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL----GERPPPRPRRP 997
G G + + G GS G G G+ G P P+ P
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281
Query: 998 -----------RTQAPGSRADPAPR-VPRAAALP----EETRSSRRRRLPPRKDPRKRKA 1041
R APG+ P PR P P E+ + P P K
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGPKG 1340
Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGP-------GFRGRRGRGEKRK 1094
G G LKI+ E +P P GP G RG+ G+ K
Sbjct: 1341 PPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400
Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGS 1133
T GP ++ K K AG DG P + G S
Sbjct: 1401 ----TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDS 1435
Score = 69.3 bits (168), Expect = 7e-11
Identities = 200/845 (23%), Positives = 263/845 (31%), Gaps = 154/845 (18%)
Query: 477 PQSAPLPWPQVLPTARPSPH-GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR---- 531
PQ LP VL A P+ G + G + + G +G G G +PG +
Sbjct: 9 PQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPG-SPGQKGFTG 67
Query: 532 -EKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASP 588
E LP + +G G P L G+ P F G +P T V G S
Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127
Query: 589 SESP-----LPSPATNTAGSTCSSLSPMSSSPANPSSEESQ------LPGPLGPSAFFHP 637
S+ LP + L +PA E LPG GP P
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187
Query: 638 PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEV 697
P P G P P F FP +G G + E H+G E
Sbjct: 188 PGFPGPVG----------------PPGPPGFFGFPG-AMGPRGPKGHMGERVIGHKG-ER 229
Query: 698 GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLL 757
G GL G P PP V++T D N + L
Sbjct: 230 GVKGLTG-PPGPPG----------------TVIVTLTGPD-NRTDL-------------- 257
Query: 758 ARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817
+ + G + + G PG P P P + G GD +GK
Sbjct: 258 -KGEKGDKGAMGEPGPPGPSGLPGESYGSEKG---------APGDPGLQGK--------- 298
Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877
P P P S+ ++ + L+ E +G++ Q D P G R
Sbjct: 299 PGKDGVP-GFPGSE-GVKGNRGFPGLMGE--DGIKGQK-------------GDIGPPGFR 341
Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPR--PGDRGCPARGRPKTRSLGLAPTE 935
GP+ + + G E PP P PQ P PG G P RP R G
Sbjct: 342 GPTEYYDTYQEKG--DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR--GAPGWP 397
Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP--- 992
S+G + R GK + + G+ +GS G + G D + + PP
Sbjct: 398 GLKGSKGERGRPGKDA------MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451
Query: 993 -------RPRRPRTQA----PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKA 1041
P P PG P +P LP + +P R+ K
Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP-----PRGPGFRGRRGRGEKRKEV 1096
G+ G + + E E QP P PG RG+ GR + +
Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGR-KGLDGI 570
Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAA 1156
T G + K A E G G P +P PG P P GP E G
Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG--EPGLQG 628
Query: 1157 REGGPKCADRPSVA-PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215
+G P P A P+ L V T P P P P +
Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVST---------PVPGPPGPPGPPGHPGPQGPPGIPGSL 679
Query: 1216 ALRSPPAACA--GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273
P GE G PG+ P PP + D G P GSL G PG L
Sbjct: 680 GKCGDPGLPGPDGEPGI-PGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737
Query: 1274 LGGPG 1278
G G
Sbjct: 738 PGAKG 742
Score = 67.4 bits (163), Expect = 3e-10
Identities = 285/1227 (23%), Positives = 374/1227 (30%), Gaps = 204/1227 (16%)
Query: 1682 AEGDSRPPQDVCLPEPS--KQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739
A G+ PP LP S + G D G K D FP E R
Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP-------GSEGVKGNRG 318
Query: 1740 LPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASP 1799
P G + E G Q +G P F P + +G P P G
Sbjct: 319 FP-----GLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-----PPGPRG 366
Query: 1800 SHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVS 1857
+ QG S G G P + RPG G P G+ G++A P SP C
Sbjct: 367 ARGPQGPS-GPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP-GSPGCAG 424
Query: 1858 NTHPSRRSQDPALSPP------------------IRQLQLPGPGVAKSKDGILGLQELTP 1899
+ P PP + +PG K + G+L Q P
Sbjct: 425 S--PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ--CP 480
Query: 1900 AAQSPPRV-NPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958
PP + GL G G+ +GSPG T LP G A G GL
Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP---GAQGDPGLK 537
Query: 1959 GQAEKTQGQGTANQLQPENGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAA 2017
G+ +T LQPE V PG + G T G L KG A
Sbjct: 538 GEKGET--------LQPEGQVGVPGDPGLRGQPGRKGLDGIPG-TPGVKGLPGPKGELAL 588
Query: 2018 MSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077
+ + P P SP A +G G P+ PGL G P
Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPA-------GPAGPPGYGPQ--GEPGLQGTQGVPGAPGPP 639
Query: 2078 SV----GDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133
G+L+ P P P GP P P G LG P P G
Sbjct: 640 GEAGPRGELSVSTPVPGP----PGPPGPPGHPGP-QGPPGIPGSLG--KCGDPGLPGPDG 692
Query: 2134 PQQLLACSPAWAPLEEAD-GVQATTDT----GAEDSPVAP--PSLTTSPCDPKEALAGCL 2186
+ P + D G T + G P P P L + +P A+ G
Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-- 750
Query: 2187 LQGEGS---PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243
G G+ P E +S G + TP + L P R + P P
Sbjct: 751 --GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGP 805
Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302
P P A GL+ G + Q G RG GP +G P DR + S
Sbjct: 806 PGRCIEGPRGAQGLPGLN----GLKGQQGRRGKTGP----KGDPGIPGLDRSGFPGETGS 857
Query: 2303 PSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK--EPEDPGTPETGRS 2360
P G P P L G D + G G P +PGTP G+
Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP--GQR 915
Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420
G+ +P V G+ P + +P + +G+P
Sbjct: 916 GSPGIPGVK--------GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP--------GL 959
Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480
+G+ P N R PG+ K K P P P P
Sbjct: 960 KGFAGNPGEKGN---------------------RGVPGMPGLKGLKGLPGPAGPPGPRGD 998
Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP--PPAQGSKEVLRAPG 2538
P EP + P + + G + + G P +P P G + PG
Sbjct: 999 LGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057
Query: 2539 SPHSQQLHPPSPT-----EHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593
+ PP PT ++ K +P P L P E G
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP----PGHLGPAGPEGAPGSPGSPGLPG 1113
Query: 2594 DSPSHSEGKSNKKRGKLRGRRLREESILP----------VSADVISDGRGSRPSPA---- 2639
H + +G L +R LP + D GR P PA
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD---QGRDGIPGPAGEKG 1170
Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698
A P G P A G + R A PG + G +A G TG + PG
Sbjct: 1171 ETGLLRAPP----GPRGNPGAQGAKGDRGAPGFPG-LPGRKGAMGDAGPRGPTGIEGFPG 1225
Query: 2699 DRMLCPGRMDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757
L + G P G +G+ A G GP + +G+ + GS +
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS-----MGHPGPKG 1280
Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP------DNPDTQGGVQGPEGPTP 2811
G + PP G LG P T P QG P NP G + GP GP
Sbjct: 1281 PPGTAGDMGPP-GRLGAPGTPGLPGPRGDPG-FQGFPGVKGEKGNPGFLGSI-GPPGPI- 1336
Query: 2812 DASGSSAKDPPSLFDDEVSFSQLFPPG 2838
K PP + D + + PG
Sbjct: 1337 -----GPKGPPGVRGDPGTLKIISLPG 1358
Score = 65.1 bits (157), Expect = 1e-09
Identities = 176/713 (24%), Positives = 227/713 (31%), Gaps = 137/713 (19%)
Query: 28 GHPSQP-PLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSST 86
G P QP P + P R +G R A G L Q R+ + G P + G S
Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851
Query: 87 PGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQ 146
PG+ GSP P + + + G P ILG P ++
Sbjct: 852 PGETGSPGIPGHQGEMGPLGQ-----RGYPGNPGILG-------PPGEDGVIGMMGFPGA 899
Query: 147 LPEVDTPQGPGT----GAPLRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSA 201
+ P PGT G+P PG+ P A+ E G S + P
Sbjct: 900 IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL 959
Query: 202 TPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKG 261
PG +RG P PG G P A P + G EP +G
Sbjct: 960 KGFAGNPGEKGNRGV-PGMPG------LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012
Query: 262 --------SRPGGSPRGVSFQFP-------FPALHG-----------ASTKPFPADVAGH 295
PG + + FP P +HG T+P P G
Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGD 1072
Query: 296 AFTNGPL----VFAFHQPQG----AWPEEAVGTGPAYPLPTQPAPSPLPCYQG-----QP 342
G + P G A PE A G+ + LP +P P ++G P
Sbjct: 1073 PGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP 1132
Query: 343 GGLNRHSDLSGALSSPG--------AAHSAPRPFSDSLHKSLTKIL--PERPPSAQDGLG 392
G+ L G SPG P P + L + P P AQ G
Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192
Query: 393 STRGPPSSLPQRHFPGQAYRASGV-DTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTP 451
RG P FPG R + D P P PGPP LP P P
Sbjct: 1193 D-RGAPG------FPGLPGRKGAMGDAGPRGPTGIEGFPGPP--GLPGAIIPGQTGNRGP 1243
Query: 452 PGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP 511
PG + SPG AP P P P G ++ G
Sbjct: 1244 PG------------SRGSPG--------APGP---------PGPPGSHVI--------GI 1266
Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571
+ GS G G G + P R G+P L G DPG Q F GV + +
Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG--DPGFQG-FPGVKGEKGN 1323
Query: 572 PHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSE-ESQLPGP-- 628
P S+ PP +G P T S S P +P P + E PGP
Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP-PGTPGEPGMQGEPGPPGPPG 1382
Query: 629 -LGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEG 680
LGP P + G+P P+ E + + +K P PA G G
Sbjct: 1383 NLGPCGPRGKPGKDGKPGTPGPAGEKGN--------KGSKGEPGPAGSDGLPG 1427
Score = 58.9 bits (141), Expect = 9e-08
Identities = 116/476 (24%), Positives = 150/476 (31%), Gaps = 78/476 (16%)
Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488
G PG+K +P + +PG A PG PRG P L + +
Sbjct: 964 GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG-----PRGDLGSTGNPGEPGLRGIPGSMG 1018
Query: 3489 ----PST-----TKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRG 3539
P + T G+P RP P H ++G + + E P P P G
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPG-PPGPTGDPGLPG 1077
Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG----QDAEGKRAPLVFSG 3594
D G + +P G GP P LP +PG G + +G P G
Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137
Query: 3595 KRRAPGARGRCAPDHFQEDHLLQ-----KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649
PG G P + D ++ + + + GPRG G Q
Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN---------PGAQ 1188
Query: 3650 SSSKDRSAASTPS----KALKFPVHPRKAVGSLA-------PGELARGTENGMKPATPKA 3698
+ DR A P K PR G PG + G P +
Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248
Query: 3699 KPG-PSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756
PG P G GS G K GS P P P + P R
Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPG--------------PKGPPGTAGDMGPPGRL 1294
Query: 3757 QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP 3816
A P G GP G P +G K +KG PG +GS G P P P
Sbjct: 1295 GA------PGTPGLPGPRGD--PGFQGFPGVKGEKGN-PG-----FLGSIG--PPGPIGP 1338
Query: 3817 PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
P + P L P S P P + EPG LG P+G+P
Sbjct: 1339 KGPPGVRGDPG-TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393
Score = 46.2 bits (108), Expect = 6e-04
Identities = 119/452 (26%), Positives = 148/452 (32%), Gaps = 83/452 (18%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG+PGQK LP + PG P GS + LP
Sbjct: 57 PGSPGQKGFTGPEGLPGPQGPKGFPG--------LPGLTGSKGVRGISGLPGF------- 101
Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP--PPSLS----PFPAALADGRGDC 3541
S + G P T + GC Q P P +L P A L +G
Sbjct: 102 --SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159
Query: 3542 AL--DGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAP 3599
A D L+ + PG+PGP Q LP P P G P F G P
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGP-------VGPPGPPGFFG---FP 206
Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP---AGCQSSSKDRS 3656
GA G P + ++ + E + GP GT + T P + D+
Sbjct: 207 GAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIV-TLTGPDNRTDLKGEKGDKG 265
Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG-------PSSQGS 3707
A P P P S PGE + G+E G P P + KPG P S+G
Sbjct: 266 AMGEPG-----PPGP-----SGLPGE-SYGSEKG-APGDPGLQGKPGKDGVPGFPGSEGV 313
Query: 3708 GSPR--PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765
R PG G + Q G + P + + E P GP
Sbjct: 314 KGNRGFPGLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-------PPGP 364
Query: 3766 REA-GEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824
R A G QGP G G SS +G P S G GR P +P
Sbjct: 365 RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAG 424
Query: 3825 TPSRVLPTKPKPNSQNKPRPPPS-EQRKAEPG 3855
+P LP P P P PP RK PG
Sbjct: 425 SPG--LPGSPGP-----PGPPGDIVFRKGPPG 449
Score = 44.3 bits (103), Expect = 0.002
Identities = 115/447 (25%), Positives = 136/447 (30%), Gaps = 89/447 (19%)
Query: 3414 RGGRQPFAFRG-VRRPGAPGQKARALEGTLP--SKRRRVAMPGSAPGPGEDRPPPRGSSP 3470
+G R F G RPG PG + P S+ R PG PG P G
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG--LPGDMGKKG 1083
Query: 3471 ILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP------IRGCELPSNHQECPP 3524
+ + P L P G P + P P H I+G P + P
Sbjct: 1084 EMGQPGPPGHL---GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--P 1138
Query: 3525 PSLSPFPAALADG--RGDCALDG----ALERPEN---------EASPGSPGPLLQQALPL 3569
P L FP + RGD DG A E+ E +PG+ G + P
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198
Query: 3570 GASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628
LP R GA G G R P G PG G P
Sbjct: 1199 FPGLPGRKGAMGD--AGPRGPTGIEGFPGPPGLPGAIIPGQ------------------T 1238
Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGT 3687
GP G+ A P G S S P P G + P G L
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA-- 1296
Query: 3688 ENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR-- 3745
P TP PGP PG K G + P G L S P P P
Sbjct: 1297 -----PGTP-GLPGPRGDPGFQGFPGVK---GEKGNP--GFLGSIGPPGPIGPKGPPGVR 1345
Query: 3746 -------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792
SP P P + E G GP G+LGP K K
Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQG------EPGPPGPPGNLGPCGPRGKPGKDGKP 1399
Query: 3793 QVPGPARSE-SVGSFGR-APSAPDKPP 3817
PGPA + + GS G P+ D P
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGSDGLP 1426
Score = 40.8 bits (94), Expect = 0.027
Identities = 117/495 (23%), Positives = 146/495 (29%), Gaps = 74/495 (14%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG PG K LP + +A+ G G P SP + + P E
Sbjct: 571 PGTPGVKG------LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP 624
Query: 3488 APSTTKGWPETLERPVDP-------VTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG 3539
T+G P P + V+ P+ G P P P P P +L G
Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL----G 680
Query: 3540 DCALDGALERPENEAS------PGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF 3592
C D L P+ E PG PGP Q P SL PG G+
Sbjct: 681 KCG-DPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG--------L 731
Query: 3593 SGKRRAPGARGR--CAPDHFQEDHLLQKEKEVSSSH----MVSEGGPRGTFHKGSATKPA 3646
GK PGA+G A E+ S H + G GT P
Sbjct: 732 PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791
Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT-PKAKPG---- 3701
G P + ++ PR A G PG + G + T PK PG
Sbjct: 792 GDPGQPGPPGEQGPPGRCIE---GPRGAQG--LPGLNGLKGQQGRRGKTGPKGDPGIPGL 846
Query: 3702 --------------PSSQGSGSP--RPGTKTGGGSQPQPAS----GQLQSETATTPAKPS 3741
P QG P + G G P G + A P P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 3742 FPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPGP 3797
+P P K P GEQG G+ GP E G+ KG P
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966
Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHT 3857
+ G G K P P L + P P S PG
Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026
Query: 3858 QRKDRLGKAFPQGRP 3872
++ LG GRP
Sbjct: 1027 GKRGTLGFPGRAGRP 1041
Score = 37.7 bits (86), Expect = 0.23
Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 9/115 (7%)
Query: 3176 RGQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAK 3235
RGQ R D G+ G+ V L E A +G + GSPG P G G A
Sbjct: 559 RGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAG 614
Query: 3236 KDSPGERAKPRARSTPS-----NPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285
G + +P + T P G A P + + G PGPP P P
Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Score = 35.0 bits (79), Expect = 1.5
Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%)
Query: 3183 LGDLPG-----GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKD 3237
L LPG G+ G A L S P G A G PG G++GE +
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK-GEKGETLQP 546
Query: 3238 S--------PGERAKPRARST---PSNPDGAATPDSASATALA----DAGSPGPPRTTPS 3282
PG R +P + P P P AL+ D G PG P + S
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606
Query: 3283 PSPDPWAG-------GEPLLQAT 3298
P P AG GEP LQ T
Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGT 629
Score = 32.3 bits (72), Expect = 9.5
Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 28/116 (24%)
Query: 3205 EPAPKHHRGK--RSAGKAAGSPGDPWGQEGEAKKDS----PGERAKPRARSTPS------ 3252
EP P G S G G+PGDP G +G+ KD PG R P
Sbjct: 269 EPGPPGPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327
Query: 3253 --------NPDGAATPDSASAT--ALADAGSPGPP-----RTTPSPSPDPWAGGEP 3293
P G P T D G+PGPP R PS P G P
Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 90.9 bits (224), Expect = 2e-17
Identities = 255/1046 (24%), Positives = 328/1046 (31%), Gaps = 188/1046 (17%)
Query: 1 MPG-ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED--NTPATRTTKGAREAGGQAQA 57
+PG + P+G P T Q + PG P P L P + G + + G
Sbjct: 462 IPGVDGPKGEPGLLCT---QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518
Query: 58 MELPEAQPRQARDGELKPPSLRGQA-----PSSTPGKRGSP--QTPPGRSPLQAPSRLAG 110
LP G+ P L+G+ P G G P + PGR L G
Sbjct: 519 TGLPGFPGFPGAQGD---PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575
Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGP-GTGAPLRPGLPRT 169
+G P + L ++ + P +P P P GP G G PGL T
Sbjct: 576 -VKGLPGPKGELALSGEKGDQGPPGDPGSPGS-----PGPAGPAGPPGYGPQGEPGLQGT 629
Query: 170 EAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQ--PGSYPEY 227
+ P A PP S S TP P PGPP G Q PG
Sbjct: 630 QGVPGAPG---------PPGEAGPRGELSVS-TPVPGPPGPPGPPGHPGPQGPPGIPGSL 679
Query: 228 QASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSR--PGGSPR-GVSFQFPFPALHGA 283
G P P E PG F PP PKG + PG G + P L G
Sbjct: 680 GKCGDPGLPGPDGEPGIPGIGFPGPPG-----PKGDQGFPGTKGSLGCPGKMGEPGLPGK 734
Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQP 342
P A GP F +G E P P LP P L +G P
Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794
Query: 343 GGLNRHSDLSGALSSPGAAHSAPR-----PFSDSLH-------KSLTKILPERPPSAQDG 390
G G PG PR P + L K+ K P P + G
Sbjct: 795 G----QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850
Query: 391 LGSTRGPPS---------SLPQRHFPGQA--------------YRASGVDTSPGPPDT-- 425
G P L QR +PG G PGPP
Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910
Query: 426 ---ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPL 482
+ +PG P + Q P A G P + S + PG L A
Sbjct: 911 TPGQRGSPGIPGVK-GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG----LKGFAGN 965
Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK--------- 533
P + P G++ L LP PAG P G +G LG+ G P +
Sbjct: 966 PGEKG-NRGVPGMPGLKGLKGLPGPAGPP----GPRGDLGSTGNPGEPGLRGIPGSMGNM 1020
Query: 534 -LPAVRSSQG--------GSPALFTYNGMTDPGAQPLFFGVAQP-QVSPHGTPSLPPPRV 583
+P + +G G P L +G+ +P + +P P G P LP
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080
Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSS-PANPSSEESQ----LPGPLGPSAFFHPP 638
+ P P AG + SP S P P + G LGP PP
Sbjct: 1081 KKGEMGQ-PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139
Query: 639 THPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVG 698
P GSP P + P PA G +G L P P P G
Sbjct: 1140 GLPGFPGSPGPMGIRGD--------QGRDGIPGPA---GEKGETGLLRAPPGPRGNP--G 1186
Query: 699 RGGLQGFPRAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLL 756
G +G AP P P ++ A R + + F G +
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAG-------------PRGPTGIEGFPGPPGLPGAI 1233
Query: 757 LA-----RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811
+ R G + SPG PG P PP + + G + H G A G
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293
Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871
L P L P P D + G++ + NP F+
Sbjct: 1294 LGAPGTPGL-----PGPRGDPGF-----------QGFPGVKGEKGNP----GFLGSIGPP 1333
Query: 872 EPSGPRGPSS--GHPLKSKAGVTPESKAPPPLPA-----ATPDPQTPRPGDRG-CPARGR 923
P GP+GP G P K P S PP P P P P PG+ G C RG+
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP-PGNLGPCGPRGK 1392
Query: 924 PKTRSLGLAPTEADAPSQGRQQRRGK 949
P G T A +G + +G+
Sbjct: 1393 PGKD--GKPGTPGPAGEKGNKGSKGE 1416
Score = 86.7 bits (213), Expect = 4e-16
Identities = 353/1494 (23%), Positives = 441/1494 (29%), Gaps = 412/1494 (27%)
Query: 184 FQEPPSSFTSTNYTSPSATPRPPAP----------GPPQSRGTS-----------PLQPG 222
F PP S +T P P P P G RG S P PG
Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPG 112
Query: 223 SYPEYQASGADSWPPA-AENSFPG--ANFGVP--------------PAEPEPIPKGSR-- 263
+ Y G + E FPG G P PA+ E I ++
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172
Query: 264 PG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG-- 319
PG G+P P P G P P G GP P+G E +G
Sbjct: 173 PGLPGAPGPQGLPGP-PGFPGPVGPPGPPGFFGFPGAMGP-----RGPKGHMGERVIGHK 226
Query: 320 --------TGPAYP----LPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAP 365
TGP P + T P +G+ G G G PG ++ +
Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286
Query: 366 R--PFSDSLHKSLTKI-LPERPPSAQDGLGSTRGPPSSLPQRHFPGQ------------- 409
+ P L K +P P S +G+ RG P + + GQ
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGS--EGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344
Query: 410 ----AYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP-YPTPPGGPLAATR---- 460
Y+ G + +PGP PGP AR PQ P+ P P PG R
Sbjct: 345 EYYDTYQEKGDEGTPGP-------PGPRGARGPQ--GPSGPPGVPGSPGSSRPGLRGAPG 395
Query: 461 ------SMFFNGQP------SPGQRLC-----LPQSAPLPWPQ---VLPTARPSPHGME- 499
S G+P +PG C LP S P P V P HG+
Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455
Query: 500 -------------------MLSRLPFPAGGPEWQG-----------GSQGALGTAGKTPG 529
+ ++ P+ G P G G QGA G G
Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515
Query: 530 P-REKLPAVRSSQG--GSPALFTYNGMT-----------DPG--AQPLFFGVAQPQVSPH 573
P LP G G P L G T DPG QP G+ +P
Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP- 574
Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPS 632
G LP P+ A E P G S SP + PA P Q PG G
Sbjct: 575 GVKGLPGPKGELALSGEKGDQGP----PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630
Query: 633 AFFHPPTHPQETG--------SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQC 684
P P E G +P P P P P H P+ P G G
Sbjct: 631 GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---- 686
Query: 685 LEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLA 744
P E G G+ GFP P P F + SL
Sbjct: 687 -----LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG------------------- 721
Query: 745 AFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQ 804
K G PG PGLP P V G T G+
Sbjct: 722 -------------CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG------TPGFPGERG 762
Query: 805 AEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSF 864
G+ + LP L TP E L+G P
Sbjct: 763 NSGEHGEIGLPGLPGLPGTPG-------------------NEGLDGPRGDPGQP------ 797
Query: 865 IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924
P G +GP G ++ G ++ P L Q R G G +G P
Sbjct: 798 -------GPPGEQGP-PGRCIEGPRG----AQGLPGLNGL--KGQQGRRGKTG--PKGDP 841
Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984
L + + S G +G+ L ++ G G L P D
Sbjct: 842 GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR-------------GYPGNPGILGPPGED 888
Query: 985 GL--------GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDP 1036
G+ PP P P T PG R P +P +R P K
Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGT--PGQRGSPG--IPGVKG---------QRGTPGAKGE 935
Query: 1037 RKRKARGGAWGKELILKIVQQKNRLREYDFA-SESEEDEQPPPRGPGFRGRRGRGEKRKE 1095
+ K G G I ++ K FA + E+ + P PG +G +G
Sbjct: 936 QGDK---GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL------ 986
Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155
P P PR G G+ NP EP G R PG P + G
Sbjct: 987 ------PGPAGPPGPR-------GDLGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTL 1032
Query: 1156 AREGGPKCADRPSVAPKDPLQVPTNTE-TSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214
G P A RP + LQ SE TRP P T + P
Sbjct: 1033 ---GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP-------TGDPGLPGD---- 1078
Query: 1215 EALRSPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272
GEMG PG L P P + G+P G PHG G+
Sbjct: 1079 -------MGKKGEMGQPGPPGHLGPAGPEGA---PGSPGSPGLPGKPGPHGDLGFKGIKG 1128
Query: 1273 LLGGPG-----------------GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPS 1315
LLG PG G + + PA + GE A P P
Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP--- 1185
Query: 1316 VLSSKISSFGCDPAGFNRDPLGVP--VAKKGPQPYSSPHS----ELFLGPKDLAGCFLEE 1369
G A +R G P +KG + P E F GP L G +
Sbjct: 1186 ---------GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236
Query: 1370 L---HPKPSARDAP-------PASSSCLCQDGEDAGSLEPQLPRSPPGTAET--EPGRAA 1417
P +R +P P S + G D GS+ P+ PPGTA PGR
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKG-DKGSMGHPGPKGPPGTAGDMGPPGRLG 1295
Query: 1418 SPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLP--FACADPPQKTVPSDPP 1469
+P T P LP R DP G + G P PP P PP
Sbjct: 1296 APGT-------PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342
Score = 77.8 bits (190), Expect = 2e-13
Identities = 289/1237 (23%), Positives = 378/1237 (30%), Gaps = 221/1237 (17%)
Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPIPKGS 262
PGPP + + P + + + D P + PG ++G P
Sbjct: 238 PGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297
Query: 263 RPG-----GSP--RGVSFQFPFPALHGAS-TKPFPADVAGHAFTNGPLVFAFHQPQGAWP 314
+PG G P GV FP L G K D+ F + +Q +G
Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG--- 354
Query: 315 EEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372
+ GP P + PS P G PG + L GA PG S
Sbjct: 355 -DEGTPGPPGPRGARGPQGPSGPPGVPGSPG--SSRPGLRGAPGWPGLKGSKG------- 404
Query: 373 HKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP 432
ER +D +G T G P PG PGPP + GP
Sbjct: 405 ---------ERGRPGKDAMG-TPGSPGCAGSPGLPGSP-------GPPGPPGDIVFRKGP 447
Query: 433 PPAR-LP-QLWDPTAAPYPTPPGGP-LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489
P LP L P P G P L T+ + G P L +P Q
Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507
Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL-----PAVRSSQG-- 542
+ SP G + LP G P QG G G G+T P ++ P +R G
Sbjct: 508 GLKGSP-GSPGNTGLPGFPGFPGAQG-DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565
Query: 543 ---GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH--GTPSLPPPRVVGASPSESPLPSPA 597
G P G+ P + G Q P G+P P P P P P
Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625
Query: 598 TN-TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP--------- 647
T G + P + P S + +PGP GP PP HP G P
Sbjct: 626 LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG---PPGHPGPQGPPGIPGSLGKC 682
Query: 648 ----FPSPEPPHSLPTHYQPEPA-----KAFPFPADGLGAEG------------------ 680
P P+ +P P P + FP LG G
Sbjct: 683 GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742
Query: 681 ----AFQCLEETP-FPHEGPEVGRGGLQGFPRAPP-PYPTHHFSLSSASLD--------Q 726
A TP FP E G G G P P P + L D +
Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802
Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL-----PSPPAAPR 781
C + R L + G R K G + PG PGL P +P
Sbjct: 803 QGPPGRCIEGPRGAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPG 859
Query: 782 VPA-DAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFP-----LPASDLDME 835
+P G L G G+D + P P P P
Sbjct: 860 IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919
Query: 836 DDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT--P 893
T G + NP S V D+ G +G + K GV P
Sbjct: 920 IPGVKGQRGTPGAKGEQGDKGNPG-PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978
Query: 894 ESKAPP--PLPAATPDPQ-----TPRPGDRGCPARGRPKTR-SLGLAPTEADAPSQGRQQ 945
K P PA P P+ T PG+ G RG P + ++G+ ++ + G
Sbjct: 979 GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPG 1036
Query: 946 RRGKQ----LKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQA 1001
R G+ + + D G +EG+ G G P + GL P ++
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG------PTGDPGL---PGDMGKKGEMGQ 1087
Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061
PG P P A S LP + P G G + I K L
Sbjct: 1088 PGPPGHLGPAGPEGAP-----GSPGSPGLPGKPGPH------GDLGFKGI------KGLL 1130
Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR-------GEKRKE--VELTQGPREDEPQKPR 1111
P GP G RG +GR GEK + + GPR + +
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190
Query: 1112 KAARQEAGGDGAP--------ANPEEPGGSR--PGPGRSPQARGPSRSLETGAAAREGGP 1161
K R G G P A P P G PGP P A P ++ G G P
Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250
Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS------TEFTE 1215
AP P ++ + + S+ P P TA + P T
Sbjct: 1251 G-------APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP 1303
Query: 1216 ALRSPPA-----ACAGEMG--------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH 1262
R P GE G PG + P+ PP R D GT K + P
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363
Query: 1263 GSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297
G+ PG+ G GP G P K +PG
Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400
Score = 69.7 bits (169), Expect = 5e-11
Identities = 281/1179 (23%), Positives = 364/1179 (30%), Gaps = 217/1179 (18%)
Query: 65 PRQAR--DGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122
PR AR G PP + G SS PG RG+P P + R A G+P
Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP--- 420
Query: 123 GIASSRTKPTLDETPENP-----------------QLEAAQLPEVDTPQG-PG---TGAP 161
G A S P P P L + +P VD P+G PG T P
Sbjct: 421 GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP 480
Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP 221
PG P P G ++ + SP T P PG P ++G L+
Sbjct: 481 YIPGPPGLPGLPGLH--GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538
Query: 222 GSYPEYQASGADSWP--PAAENSFPGANF-----GVPPAEPEPIPKGSRPGGSPRGVSFQ 274
Q G P P PG G P + P PKG +G Q
Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKG--DQ 595
Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSP 334
P P G+ P PA AG P G P+ G +P P P
Sbjct: 596 GP-PGDPGSPGSPGPAGPAG--------------PPGYGPQGEPGLQGTQGVPGAPGP-- 638
Query: 335 LPCYQGQPGGLNRHSDLSGALSSPG-AAHSAPR---PFSDSLHKSLTKILPERPPSAQDG 390
P G G L+ + + G PG H P+ SL K LP P + G
Sbjct: 639 -PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP--GPDGEPG 695
Query: 391 LGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY 448
+ GPP + FPG G PG ++ PG P P L P
Sbjct: 696 IPGIGFPGPPGPKGDQGFPG----TKGSLGCPG----KMGEPGLPGK--PGLPGAKGEPA 745
Query: 449 PTPPGGPLAATRSMFFNGQPS-PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP 507
PGGP G P PG+R HG L LP
Sbjct: 746 VAMPGGP----------GTPGFPGER-----------------GNSGEHGEIGLPGLPGL 778
Query: 508 AGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGV 565
G P G G G G+ P E+ P R +G G+ L NG+ +
Sbjct: 779 PGTP-GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR------ 831
Query: 566 AQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPS---- 619
+ + P G P +P G S P + + G + P+ P NP
Sbjct: 832 -RGKTGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQ-GEMGPLGQRGYPGNPGILGP 884
Query: 620 -SEESQL-----PGPLGPSAFFHPPTHPQETGSP-FPSPEPPHSLPTHYQPEPAKAFPFP 672
E+ + PG +GP P P + GSP P + P + K P P
Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944
Query: 673 AD-----GLGAEGAFQCLEETPFPHEGPEV----GRGGLQGFP-RAPPPYPTHHFSLSS- 721
++ G E + P V G GL+G P A PP P +
Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004
Query: 722 ----------ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG-- 769
S+ + + + F GL G + PG
Sbjct: 1005 PGEPGLRGIPGSMGNMGM-----PGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059
Query: 770 ---PPGLPSPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPF 825
PG P P P +P D G + G A EG + LP
Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----- 1114
Query: 826 PLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPL 885
P P DL + L L + G P P G RG +
Sbjct: 1115 PGPHGDLGFKGIKGL--LGPPGIRGPPGLPGFP----------GSPGPMGIRGDQGRDGI 1162
Query: 886 KSKAGVTPES--KAPPPLPAATPDPQTPRPGDRGCPA-RGRP-KTRSLGLAPTEADAPSQ 941
AG E+ PP P P Q + GDRG P G P + ++G A +
Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221
Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL----GERPPPRPRRP 997
G G + + G GS G G G+ G P P+ P
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281
Query: 998 -----------RTQAPGSRADPAPR-VPRAAALP----EETRSSRRRRLPPRKDPRKRKA 1041
R APG+ P PR P P E+ + P P K
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGPKG 1340
Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGP-------GFRGRRGRGEKRK 1094
G G LKI+ E +P P GP G RG+ G+ K
Sbjct: 1341 PPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400
Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGS 1133
T GP ++ K K AG DG P + G S
Sbjct: 1401 ----TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDS 1435
Score = 69.3 bits (168), Expect = 7e-11
Identities = 200/845 (23%), Positives = 263/845 (31%), Gaps = 154/845 (18%)
Query: 477 PQSAPLPWPQVLPTARPSPH-GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR---- 531
PQ LP VL A P+ G + G + + G +G G G +PG +
Sbjct: 9 PQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPG-SPGQKGFTG 67
Query: 532 -EKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASP 588
E LP + +G G P L G+ P F G +P T V G S
Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127
Query: 589 SESP-----LPSPATNTAGSTCSSLSPMSSSPANPSSEESQ------LPGPLGPSAFFHP 637
S+ LP + L +PA E LPG GP P
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187
Query: 638 PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEV 697
P P G P P F FP +G G + E H+G E
Sbjct: 188 PGFPGPVG----------------PPGPPGFFGFPG-AMGPRGPKGHMGERVIGHKG-ER 229
Query: 698 GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLL 757
G GL G P PP V++T D N + L
Sbjct: 230 GVKGLTG-PPGPPG----------------TVIVTLTGPD-NRTDL-------------- 257
Query: 758 ARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817
+ + G + + G PG P P P + G GD +GK
Sbjct: 258 -KGEKGDKGAMGEPGPPGPSGLPGESYGSEKG---------APGDPGLQGK--------- 298
Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877
P P P S+ ++ + L+ E +G++ Q D P G R
Sbjct: 299 PGKDGVP-GFPGSE-GVKGNRGFPGLMGE--DGIKGQK-------------GDIGPPGFR 341
Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPR--PGDRGCPARGRPKTRSLGLAPTE 935
GP+ + + G E PP P PQ P PG G P RP R G
Sbjct: 342 GPTEYYDTYQEKG--DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR--GAPGWP 397
Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP--- 992
S+G + R GK + + G+ +GS G + G D + + PP
Sbjct: 398 GLKGSKGERGRPGKDA------MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451
Query: 993 -------RPRRPRTQA----PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKA 1041
P P PG P +P LP + +P R+ K
Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP-----PRGPGFRGRRGRGEKRKEV 1096
G+ G + + E E QP P PG RG+ GR + +
Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGR-KGLDGI 570
Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAA 1156
T G + K A E G G P +P PG P P GP E G
Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG--EPGLQG 628
Query: 1157 REGGPKCADRPSVA-PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215
+G P P A P+ L V T P P P P +
Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVST---------PVPGPPGPPGPPGHPGPQGPPGIPGSL 679
Query: 1216 ALRSPPAACA--GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273
P GE G PG+ P PP + D G P GSL G PG L
Sbjct: 680 GKCGDPGLPGPDGEPGI-PGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737
Query: 1274 LGGPG 1278
G G
Sbjct: 738 PGAKG 742
Score = 67.4 bits (163), Expect = 3e-10
Identities = 285/1227 (23%), Positives = 374/1227 (30%), Gaps = 204/1227 (16%)
Query: 1682 AEGDSRPPQDVCLPEPS--KQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739
A G+ PP LP S + G D G K D FP E R
Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP-------GSEGVKGNRG 318
Query: 1740 LPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASP 1799
P G + E G Q +G P F P + +G P P G
Sbjct: 319 FP-----GLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-----PPGPRG 366
Query: 1800 SHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVS 1857
+ QG S G G P + RPG G P G+ G++A P SP C
Sbjct: 367 ARGPQGPS-GPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP-GSPGCAG 424
Query: 1858 NTHPSRRSQDPALSPP------------------IRQLQLPGPGVAKSKDGILGLQELTP 1899
+ P PP + +PG K + G+L Q P
Sbjct: 425 S--PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ--CP 480
Query: 1900 AAQSPPRV-NPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958
PP + GL G G+ +GSPG T LP G A G GL
Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP---GAQGDPGLK 537
Query: 1959 GQAEKTQGQGTANQLQPENGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAA 2017
G+ +T LQPE V PG + G T G L KG A
Sbjct: 538 GEKGET--------LQPEGQVGVPGDPGLRGQPGRKGLDGIPG-TPGVKGLPGPKGELAL 588
Query: 2018 MSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077
+ + P P SP A +G G P+ PGL G P
Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPA-------GPAGPPGYGPQ--GEPGLQGTQGVPGAPGPP 639
Query: 2078 SV----GDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133
G+L+ P P P GP P P G LG P P G
Sbjct: 640 GEAGPRGELSVSTPVPGP----PGPPGPPGHPGP-QGPPGIPGSLG--KCGDPGLPGPDG 692
Query: 2134 PQQLLACSPAWAPLEEAD-GVQATTDT----GAEDSPVAP--PSLTTSPCDPKEALAGCL 2186
+ P + D G T + G P P P L + +P A+ G
Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-- 750
Query: 2187 LQGEGS---PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243
G G+ P E +S G + TP + L P R + P P
Sbjct: 751 --GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGP 805
Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302
P P A GL+ G + Q G RG GP +G P DR + S
Sbjct: 806 PGRCIEGPRGAQGLPGLN----GLKGQQGRRGKTGP----KGDPGIPGLDRSGFPGETGS 857
Query: 2303 PSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK--EPEDPGTPETGRS 2360
P G P P L G D + G G P +PGTP G+
Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP--GQR 915
Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420
G+ +P V G+ P + +P + +G+P
Sbjct: 916 GSPGIPGVK--------GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP--------GL 959
Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480
+G+ P N R PG+ K K P P P P
Sbjct: 960 KGFAGNPGEKGN---------------------RGVPGMPGLKGLKGLPGPAGPPGPRGD 998
Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP--PPAQGSKEVLRAPG 2538
P EP + P + + G + + G P +P P G + PG
Sbjct: 999 LGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057
Query: 2539 SPHSQQLHPPSPT-----EHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593
+ PP PT ++ K +P P L P E G
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP----PGHLGPAGPEGAPGSPGSPGLPG 1113
Query: 2594 DSPSHSEGKSNKKRGKLRGRRLREESILP----------VSADVISDGRGSRPSPA---- 2639
H + +G L +R LP + D GR P PA
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD---QGRDGIPGPAGEKG 1170
Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698
A P G P A G + R A PG + G +A G TG + PG
Sbjct: 1171 ETGLLRAPP----GPRGNPGAQGAKGDRGAPGFPG-LPGRKGAMGDAGPRGPTGIEGFPG 1225
Query: 2699 DRMLCPGRMDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757
L + G P G +G+ A G GP + +G+ + GS +
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS-----MGHPGPKG 1280
Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP------DNPDTQGGVQGPEGPTP 2811
G + PP G LG P T P QG P NP G + GP GP
Sbjct: 1281 PPGTAGDMGPP-GRLGAPGTPGLPGPRGDPG-FQGFPGVKGEKGNPGFLGSI-GPPGPI- 1336
Query: 2812 DASGSSAKDPPSLFDDEVSFSQLFPPG 2838
K PP + D + + PG
Sbjct: 1337 -----GPKGPPGVRGDPGTLKIISLPG 1358
Score = 65.1 bits (157), Expect = 1e-09
Identities = 176/713 (24%), Positives = 227/713 (31%), Gaps = 137/713 (19%)
Query: 28 GHPSQP-PLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSST 86
G P QP P + P R +G R A G L Q R+ + G P + G S
Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851
Query: 87 PGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQ 146
PG+ GSP P + + + G P ILG P ++
Sbjct: 852 PGETGSPGIPGHQGEMGPLGQ-----RGYPGNPGILG-------PPGEDGVIGMMGFPGA 899
Query: 147 LPEVDTPQGPGT----GAPLRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSA 201
+ P PGT G+P PG+ P A+ E G S + P
Sbjct: 900 IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL 959
Query: 202 TPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKG 261
PG +RG P PG G P A P + G EP +G
Sbjct: 960 KGFAGNPGEKGNRGV-PGMPG------LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012
Query: 262 --------SRPGGSPRGVSFQFP-------FPALHG-----------ASTKPFPADVAGH 295
PG + + FP P +HG T+P P G
Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGD 1072
Query: 296 AFTNGPL----VFAFHQPQG----AWPEEAVGTGPAYPLPTQPAPSPLPCYQG-----QP 342
G + P G A PE A G+ + LP +P P ++G P
Sbjct: 1073 PGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP 1132
Query: 343 GGLNRHSDLSGALSSPG--------AAHSAPRPFSDSLHKSLTKIL--PERPPSAQDGLG 392
G+ L G SPG P P + L + P P AQ G
Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192
Query: 393 STRGPPSSLPQRHFPGQAYRASGV-DTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTP 451
RG P FPG R + D P P PGPP LP P P
Sbjct: 1193 D-RGAPG------FPGLPGRKGAMGDAGPRGPTGIEGFPGPP--GLPGAIIPGQTGNRGP 1243
Query: 452 PGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP 511
PG + SPG AP P P P G ++ G
Sbjct: 1244 PG------------SRGSPG--------APGP---------PGPPGSHVI--------GI 1266
Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571
+ GS G G G + P R G+P L G DPG Q F GV + +
Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG--DPGFQG-FPGVKGEKGN 1323
Query: 572 PHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSE-ESQLPGP-- 628
P S+ PP +G P T S S P +P P + E PGP
Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP-PGTPGEPGMQGEPGPPGPPG 1382
Query: 629 -LGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEG 680
LGP P + G+P P+ E + + +K P PA G G
Sbjct: 1383 NLGPCGPRGKPGKDGKPGTPGPAGEKGN--------KGSKGEPGPAGSDGLPG 1427
Score = 58.9 bits (141), Expect = 9e-08
Identities = 116/476 (24%), Positives = 150/476 (31%), Gaps = 78/476 (16%)
Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488
G PG+K +P + +PG A PG PRG P L + +
Sbjct: 964 GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG-----PRGDLGSTGNPGEPGLRGIPGSMG 1018
Query: 3489 ----PST-----TKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRG 3539
P + T G+P RP P H ++G + + E P P P G
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPG-PPGPTGDPGLPG 1077
Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG----QDAEGKRAPLVFSG 3594
D G + +P G GP P LP +PG G + +G P G
Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137
Query: 3595 KRRAPGARGRCAPDHFQEDHLLQ-----KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649
PG G P + D ++ + + + GPRG G Q
Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN---------PGAQ 1188
Query: 3650 SSSKDRSAASTPS----KALKFPVHPRKAVGSLA-------PGELARGTENGMKPATPKA 3698
+ DR A P K PR G PG + G P +
Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248
Query: 3699 KPG-PSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756
PG P G GS G K GS P P P + P R
Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPG--------------PKGPPGTAGDMGPPGRL 1294
Query: 3757 QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP 3816
A P G GP G P +G K +KG PG +GS G P P P
Sbjct: 1295 GA------PGTPGLPGPRGD--PGFQGFPGVKGEKGN-PG-----FLGSIG--PPGPIGP 1338
Query: 3817 PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
P + P L P S P P + EPG LG P+G+P
Sbjct: 1339 KGPPGVRGDPG-TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393
Score = 46.2 bits (108), Expect = 6e-04
Identities = 119/452 (26%), Positives = 148/452 (32%), Gaps = 83/452 (18%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG+PGQK LP + PG P GS + LP
Sbjct: 57 PGSPGQKGFTGPEGLPGPQGPKGFPG--------LPGLTGSKGVRGISGLPGF------- 101
Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP--PPSLS----PFPAALADGRGDC 3541
S + G P T + GC Q P P +L P A L +G
Sbjct: 102 --SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159
Query: 3542 AL--DGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAP 3599
A D L+ + PG+PGP Q LP P P G P F G P
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGP-------VGPPGPPGFFG---FP 206
Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP---AGCQSSSKDRS 3656
GA G P + ++ + E + GP GT + T P + D+
Sbjct: 207 GAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIV-TLTGPDNRTDLKGEKGDKG 265
Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG-------PSSQGS 3707
A P P P S PGE + G+E G P P + KPG P S+G
Sbjct: 266 AMGEPG-----PPGP-----SGLPGE-SYGSEKG-APGDPGLQGKPGKDGVPGFPGSEGV 313
Query: 3708 GSPR--PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765
R PG G + Q G + P + + E P GP
Sbjct: 314 KGNRGFPGLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-------PPGP 364
Query: 3766 REA-GEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824
R A G QGP G G SS +G P S G GR P +P
Sbjct: 365 RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAG 424
Query: 3825 TPSRVLPTKPKPNSQNKPRPPPS-EQRKAEPG 3855
+P LP P P P PP RK PG
Sbjct: 425 SPG--LPGSPGP-----PGPPGDIVFRKGPPG 449
Score = 44.3 bits (103), Expect = 0.002
Identities = 115/447 (25%), Positives = 136/447 (30%), Gaps = 89/447 (19%)
Query: 3414 RGGRQPFAFRG-VRRPGAPGQKARALEGTLP--SKRRRVAMPGSAPGPGEDRPPPRGSSP 3470
+G R F G RPG PG + P S+ R PG PG P G
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG--LPGDMGKKG 1083
Query: 3471 ILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP------IRGCELPSNHQECPP 3524
+ + P L P G P + P P H I+G P + P
Sbjct: 1084 EMGQPGPPGHL---GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--P 1138
Query: 3525 PSLSPFPAALADG--RGDCALDG----ALERPEN---------EASPGSPGPLLQQALPL 3569
P L FP + RGD DG A E+ E +PG+ G + P
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198
Query: 3570 GASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628
LP R GA G G R P G PG G P
Sbjct: 1199 FPGLPGRKGAMGD--AGPRGPTGIEGFPGPPGLPGAIIPGQ------------------T 1238
Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGT 3687
GP G+ A P G S S P P G + P G L
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA-- 1296
Query: 3688 ENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR-- 3745
P TP PGP PG K G + P G L S P P P
Sbjct: 1297 -----PGTP-GLPGPRGDPGFQGFPGVK---GEKGNP--GFLGSIGPPGPIGPKGPPGVR 1345
Query: 3746 -------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792
SP P P + E G GP G+LGP K K
Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQG------EPGPPGPPGNLGPCGPRGKPGKDGKP 1399
Query: 3793 QVPGPARSE-SVGSFGR-APSAPDKPP 3817
PGPA + + GS G P+ D P
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGSDGLP 1426
Score = 40.8 bits (94), Expect = 0.027
Identities = 117/495 (23%), Positives = 146/495 (29%), Gaps = 74/495 (14%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG PG K LP + +A+ G G P SP + + P E
Sbjct: 571 PGTPGVKG------LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP 624
Query: 3488 APSTTKGWPETLERPVDP-------VTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG 3539
T+G P P + V+ P+ G P P P P P +L G
Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL----G 680
Query: 3540 DCALDGALERPENEAS------PGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF 3592
C D L P+ E PG PGP Q P SL PG G+
Sbjct: 681 KCG-DPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG--------L 731
Query: 3593 SGKRRAPGARGR--CAPDHFQEDHLLQKEKEVSSSH----MVSEGGPRGTFHKGSATKPA 3646
GK PGA+G A E+ S H + G GT P
Sbjct: 732 PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791
Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT-PKAKPG---- 3701
G P + ++ PR A G PG + G + T PK PG
Sbjct: 792 GDPGQPGPPGEQGPPGRCIE---GPRGAQG--LPGLNGLKGQQGRRGKTGPKGDPGIPGL 846
Query: 3702 --------------PSSQGSGSP--RPGTKTGGGSQPQPAS----GQLQSETATTPAKPS 3741
P QG P + G G P G + A P P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 3742 FPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPGP 3797
+P P K P GEQG G+ GP E G+ KG P
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966
Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHT 3857
+ G G K P P L + P P S PG
Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026
Query: 3858 QRKDRLGKAFPQGRP 3872
++ LG GRP
Sbjct: 1027 GKRGTLGFPGRAGRP 1041
Score = 37.7 bits (86), Expect = 0.23
Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 9/115 (7%)
Query: 3176 RGQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAK 3235
RGQ R D G+ G+ V L E A +G + GSPG P G G A
Sbjct: 559 RGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAG 614
Query: 3236 KDSPGERAKPRARSTPS-----NPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285
G + +P + T P G A P + + G PGPP P P
Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Score = 35.0 bits (79), Expect = 1.5
Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%)
Query: 3183 LGDLPG-----GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKD 3237
L LPG G+ G A L S P G A G PG G++GE +
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK-GEKGETLQP 546
Query: 3238 S--------PGERAKPRARST---PSNPDGAATPDSASATALA----DAGSPGPPRTTPS 3282
PG R +P + P P P AL+ D G PG P + S
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606
Query: 3283 PSPDPWAG-------GEPLLQAT 3298
P P AG GEP LQ T
Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGT 629
Score = 32.3 bits (72), Expect = 9.5
Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 28/116 (24%)
Query: 3205 EPAPKHHRGK--RSAGKAAGSPGDPWGQEGEAKKDS----PGERAKPRARSTPS------ 3252
EP P G S G G+PGDP G +G+ KD PG R P
Sbjct: 269 EPGPPGPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327
Query: 3253 --------NPDGAATPDSASAT--ALADAGSPGPP-----RTTPSPSPDPWAGGEP 3293
P G P T D G+PGPP R PS P G P
Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 90.9 bits (224), Expect = 2e-17
Identities = 255/1046 (24%), Positives = 328/1046 (31%), Gaps = 188/1046 (17%)
Query: 1 MPG-ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLED--NTPATRTTKGAREAGGQAQA 57
+PG + P+G P T Q + PG P P L P + G + + G
Sbjct: 462 IPGVDGPKGEPGLLCT---QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGN 518
Query: 58 MELPEAQPRQARDGELKPPSLRGQA-----PSSTPGKRGSP--QTPPGRSPLQAPSRLAG 110
LP G+ P L+G+ P G G P + PGR L G
Sbjct: 519 TGLPGFPGFPGAQGD---PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575
Query: 111 RAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGP-GTGAPLRPGLPRT 169
+G P + L ++ + P +P P P GP G G PGL T
Sbjct: 576 -VKGLPGPKGELALSGEKGDQGPPGDPGSPGS-----PGPAGPAGPPGYGPQGEPGLQGT 629
Query: 170 EAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQ--PGSYPEY 227
+ P A PP S S TP P PGPP G Q PG
Sbjct: 630 QGVPGAPG---------PPGEAGPRGELSVS-TPVPGPPGPPGPPGHPGPQGPPGIPGSL 679
Query: 228 QASGADSWP-PAAENSFPGANFGVPPAEPEPIPKGSR--PGGSPR-GVSFQFPFPALHGA 283
G P P E PG F PP PKG + PG G + P L G
Sbjct: 680 GKCGDPGLPGPDGEPGIPGIGFPGPPG-----PKGDQGFPGTKGSLGCPGKMGEPGLPGK 734
Query: 284 STKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYP-LPTQPAPSPLPCYQGQP 342
P A GP F +G E P P LP P L +G P
Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794
Query: 343 GGLNRHSDLSGALSSPGAAHSAPR-----PFSDSLH-------KSLTKILPERPPSAQDG 390
G G PG PR P + L K+ K P P + G
Sbjct: 795 G----QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850
Query: 391 LGSTRGPPS---------SLPQRHFPGQA--------------YRASGVDTSPGPPDT-- 425
G P L QR +PG G PGPP
Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910
Query: 426 ---ELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPL 482
+ +PG P + Q P A G P + S + PG L A
Sbjct: 911 TPGQRGSPGIPGVK-GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG----LKGFAGN 965
Query: 483 PWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREK--------- 533
P + P G++ L LP PAG P G +G LG+ G P +
Sbjct: 966 PGEKG-NRGVPGMPGLKGLKGLPGPAGPP----GPRGDLGSTGNPGEPGLRGIPGSMGNM 1020
Query: 534 -LPAVRSSQG--------GSPALFTYNGMTDPGAQPLFFGVAQP-QVSPHGTPSLPPPRV 583
+P + +G G P L +G+ +P + +P P G P LP
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080
Query: 584 VGASPSESPLPSPATNTAGSTCSSLSPMSSS-PANPSSEESQ----LPGPLGPSAFFHPP 638
+ P P AG + SP S P P + G LGP PP
Sbjct: 1081 KKGEMGQ-PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139
Query: 639 THPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVG 698
P GSP P + P PA G +G L P P P G
Sbjct: 1140 GLPGFPGSPGPMGIRGD--------QGRDGIPGPA---GEKGETGLLRAPPGPRGNP--G 1186
Query: 699 RGGLQGFPRAP--PPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLL 756
G +G AP P P ++ A R + + F G +
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAG-------------PRGPTGIEGFPGPPGLPGAI 1233
Query: 757 LA-----RAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDP 811
+ R G + SPG PG P PP + + G + H G A G
Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293
Query: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADE 871
L P L P P D + G++ + NP F+
Sbjct: 1294 LGAPGTPGL-----PGPRGDPGF-----------QGFPGVKGEKGNP----GFLGSIGPP 1333
Query: 872 EPSGPRGPSS--GHPLKSKAGVTPESKAPPPLPA-----ATPDPQTPRPGDRG-CPARGR 923
P GP+GP G P K P S PP P P P P PG+ G C RG+
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP-PGNLGPCGPRGK 1392
Query: 924 PKTRSLGLAPTEADAPSQGRQQRRGK 949
P G T A +G + +G+
Sbjct: 1393 PGKD--GKPGTPGPAGEKGNKGSKGE 1416
Score = 86.7 bits (213), Expect = 4e-16
Identities = 353/1494 (23%), Positives = 441/1494 (29%), Gaps = 412/1494 (27%)
Query: 184 FQEPPSSFTSTNYTSPSATPRPPAP----------GPPQSRGTS-----------PLQPG 222
F PP S +T P P P P G RG S P PG
Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPG 112
Query: 223 SYPEYQASGADSWPPA-AENSFPG--ANFGVP--------------PAEPEPIPKGSR-- 263
+ Y G + E FPG G P PA+ E I ++
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172
Query: 264 PG--GSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVG-- 319
PG G+P P P G P P G GP P+G E +G
Sbjct: 173 PGLPGAPGPQGLPGP-PGFPGPVGPPGPPGFFGFPGAMGP-----RGPKGHMGERVIGHK 226
Query: 320 --------TGPAYP----LPTQPAPSPLPCYQGQPG--GLNRHSDLSGALSSPGAAHSAP 365
TGP P + T P +G+ G G G PG ++ +
Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286
Query: 366 R--PFSDSLHKSLTKI-LPERPPSAQDGLGSTRGPPSSLPQRHFPGQ------------- 409
+ P L K +P P S +G+ RG P + + GQ
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGS--EGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344
Query: 410 ----AYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAP-YPTPPGGPLAATR---- 460
Y+ G + +PGP PGP AR PQ P+ P P PG R
Sbjct: 345 EYYDTYQEKGDEGTPGP-------PGPRGARGPQ--GPSGPPGVPGSPGSSRPGLRGAPG 395
Query: 461 ------SMFFNGQP------SPGQRLC-----LPQSAPLPWPQ---VLPTARPSPHGME- 499
S G+P +PG C LP S P P V P HG+
Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPG 455
Query: 500 -------------------MLSRLPFPAGGPEWQG-----------GSQGALGTAGKTPG 529
+ ++ P+ G P G G QGA G G
Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515
Query: 530 P-REKLPAVRSSQG--GSPALFTYNGMT-----------DPG--AQPLFFGVAQPQVSPH 573
P LP G G P L G T DPG QP G+ +P
Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP- 574
Query: 574 GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ-LPGPLGPS 632
G LP P+ A E P G S SP + PA P Q PG G
Sbjct: 575 GVKGLPGPKGELALSGEKGDQGP----PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630
Query: 633 AFFHPPTHPQETG--------SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQC 684
P P E G +P P P P P H P+ P G G
Sbjct: 631 GVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---- 686
Query: 685 LEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLA 744
P E G G+ GFP P P F + SL
Sbjct: 687 -----LPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLG------------------- 721
Query: 745 AFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQ 804
K G PG PGLP P V G T G+
Sbjct: 722 -------------CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPG------TPGFPGERG 762
Query: 805 AEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSF 864
G+ + LP L TP E L+G P
Sbjct: 763 NSGEHGEIGLPGLPGLPGTPG-------------------NEGLDGPRGDPGQP------ 797
Query: 865 IDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRP 924
P G +GP G ++ G ++ P L Q R G G +G P
Sbjct: 798 -------GPPGEQGP-PGRCIEGPRG----AQGLPGLNGL--KGQQGRRGKTG--PKGDP 841
Query: 925 KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRND 984
L + + S G +G+ L ++ G G L P D
Sbjct: 842 GIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR-------------GYPGNPGILGPPGED 888
Query: 985 GL--------GERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDP 1036
G+ PP P P T PG R P +P +R P K
Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGT--PGQRGSPG--IPGVKG---------QRGTPGAKGE 935
Query: 1037 RKRKARGGAWGKELILKIVQQKNRLREYDFA-SESEEDEQPPPRGPGFRGRRGRGEKRKE 1095
+ K G G I ++ K FA + E+ + P PG +G +G
Sbjct: 936 QGDK---GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGL------ 986
Query: 1096 VELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAA 1155
P P PR G G+ NP EP G R PG P + G
Sbjct: 987 ------PGPAGPPGPR-------GDLGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTL 1032
Query: 1156 AREGGPKCADRPSVAPKDPLQVPTNTE-TSEETRPSLDFPQEAKEPETAEESAPDSTEFT 1214
G P A RP + LQ SE TRP P T + P
Sbjct: 1033 ---GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP-------TGDPGLPGD---- 1078
Query: 1215 EALRSPPAACAGEMG--ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGS 1272
GEMG PG L P P + G+P G PHG G+
Sbjct: 1079 -------MGKKGEMGQPGPPGHLGPAGPEGA---PGSPGSPGLPGKPGPHGDLGFKGIKG 1128
Query: 1273 LLGGPG-----------------GTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPS 1315
LLG PG G + + PA + GE A P P
Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP--- 1185
Query: 1316 VLSSKISSFGCDPAGFNRDPLGVP--VAKKGPQPYSSPHS----ELFLGPKDLAGCFLEE 1369
G A +R G P +KG + P E F GP L G +
Sbjct: 1186 ---------GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236
Query: 1370 L---HPKPSARDAP-------PASSSCLCQDGEDAGSLEPQLPRSPPGTAET--EPGRAA 1417
P +R +P P S + G D GS+ P+ PPGTA PGR
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKG-DKGSMGHPGPKGPPGTAGDMGPPGRLG 1295
Query: 1418 SPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLP--FACADPPQKTVPSDPP 1469
+P T P LP R DP G + G P PP P PP
Sbjct: 1296 APGT-------PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342
Score = 77.8 bits (190), Expect = 2e-13
Identities = 289/1237 (23%), Positives = 378/1237 (30%), Gaps = 221/1237 (17%)
Query: 208 PGPPQSRGTSPLQPGSYPEYQASGADSWP-----PAAENSFPGANFGVPPAEPEPIPKGS 262
PGPP + + P + + + D P + PG ++G P
Sbjct: 238 PGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297
Query: 263 RPG-----GSP--RGVSFQFPFPALHGAS-TKPFPADVAGHAFTNGPLVFAFHQPQGAWP 314
+PG G P GV FP L G K D+ F + +Q +G
Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG--- 354
Query: 315 EEAVGTGPAYPLPTQ--PAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSL 372
+ GP P + PS P G PG + L GA PG S
Sbjct: 355 -DEGTPGPPGPRGARGPQGPSGPPGVPGSPG--SSRPGLRGAPGWPGLKGSKG------- 404
Query: 373 HKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGP 432
ER +D +G T G P PG PGPP + GP
Sbjct: 405 ---------ERGRPGKDAMG-TPGSPGCAGSPGLPGSP-------GPPGPPGDIVFRKGP 447
Query: 433 PPAR-LP-QLWDPTAAPYPTPPGGP-LAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489
P LP L P P G P L T+ + G P L +P Q
Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507
Query: 490 TARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKL-----PAVRSSQG-- 542
+ SP G + LP G P QG G G G+T P ++ P +R G
Sbjct: 508 GLKGSP-GSPGNTGLPGFPGFPGAQG-DPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565
Query: 543 ---GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH--GTPSLPPPRVVGASPSESPLPSPA 597
G P G+ P + G Q P G+P P P P P P
Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625
Query: 598 TN-TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP--------- 647
T G + P + P S + +PGP GP PP HP G P
Sbjct: 626 LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG---PPGHPGPQGPPGIPGSLGKC 682
Query: 648 ----FPSPEPPHSLPTHYQPEPA-----KAFPFPADGLGAEG------------------ 680
P P+ +P P P + FP LG G
Sbjct: 683 GDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742
Query: 681 ----AFQCLEETP-FPHEGPEVGRGGLQGFPRAPP-PYPTHHFSLSSASLD--------Q 726
A TP FP E G G G P P P + L D +
Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGE 802
Query: 727 LDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGL-----PSPPAAPR 781
C + R L + G R K G + PG PGL P +P
Sbjct: 803 QGPPGRCIEGPRGAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPG 859
Query: 782 VPA-DAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFP-----LPASDLDME 835
+P G L G G+D + P P P P
Sbjct: 860 IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPG 919
Query: 836 DDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT--P 893
T G + NP S V D+ G +G + K GV P
Sbjct: 920 IPGVKGQRGTPGAKGEQGDKGNPG-PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978
Query: 894 ESKAPP--PLPAATPDPQ-----TPRPGDRGCPARGRPKTR-SLGLAPTEADAPSQGRQQ 945
K P PA P P+ T PG+ G RG P + ++G+ ++ + G
Sbjct: 979 GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPG 1036
Query: 946 RRGKQ----LKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQA 1001
R G+ + + D G +EG+ G G P + GL P ++
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG------PTGDPGL---PGDMGKKGEMGQ 1087
Query: 1002 PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRL 1061
PG P P A S LP + P G G + I K L
Sbjct: 1088 PGPPGHLGPAGPEGAP-----GSPGSPGLPGKPGPH------GDLGFKGI------KGLL 1130
Query: 1062 REYDFASESEEDEQPPPRGP-GFRGRRGR-------GEKRKE--VELTQGPREDEPQKPR 1111
P GP G RG +GR GEK + + GPR + +
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190
Query: 1112 KAARQEAGGDGAP--------ANPEEPGGSR--PGPGRSPQARGPSRSLETGAAAREGGP 1161
K R G G P A P P G PGP P A P ++ G G P
Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250
Query: 1162 KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDS------TEFTE 1215
AP P ++ + + S+ P P TA + P T
Sbjct: 1251 G-------APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP 1303
Query: 1216 ALRSPPA-----ACAGEMG--------ASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPH 1262
R P GE G PG + P+ PP R D GT K + P
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363
Query: 1263 GSSPTPGVGSLLG--GPGGTQAPVSHNSKDPPARQPG 1297
G+ PG+ G GP G P K +PG
Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400
Score = 69.7 bits (169), Expect = 5e-11
Identities = 281/1179 (23%), Positives = 364/1179 (30%), Gaps = 217/1179 (18%)
Query: 65 PRQAR--DGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122
PR AR G PP + G SS PG RG+P P + R A G+P
Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP--- 420
Query: 123 GIASSRTKPTLDETPENP-----------------QLEAAQLPEVDTPQG-PG---TGAP 161
G A S P P P L + +P VD P+G PG T P
Sbjct: 421 GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCP 480
Query: 162 LRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP 221
PG P P G ++ + SP T P PG P ++G L+
Sbjct: 481 YIPGPPGLPGLPGLH--GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538
Query: 222 GSYPEYQASGADSWP--PAAENSFPGANF-----GVPPAEPEPIPKGSRPGGSPRGVSFQ 274
Q G P P PG G P + P PKG +G Q
Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKG--DQ 595
Query: 275 FPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSP 334
P P G+ P PA AG P G P+ G +P P P
Sbjct: 596 GP-PGDPGSPGSPGPAGPAG--------------PPGYGPQGEPGLQGTQGVPGAPGP-- 638
Query: 335 LPCYQGQPGGLNRHSDLSGALSSPG-AAHSAPR---PFSDSLHKSLTKILPERPPSAQDG 390
P G G L+ + + G PG H P+ SL K LP P + G
Sbjct: 639 -PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP--GPDGEPG 695
Query: 391 LGST--RGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPY 448
+ GPP + FPG G PG ++ PG P P L P
Sbjct: 696 IPGIGFPGPPGPKGDQGFPG----TKGSLGCPG----KMGEPGLPGK--PGLPGAKGEPA 745
Query: 449 PTPPGGPLAATRSMFFNGQPS-PGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFP 507
PGGP G P PG+R HG L LP
Sbjct: 746 VAMPGGP----------GTPGFPGER-----------------GNSGEHGEIGLPGLPGL 778
Query: 508 AGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGV 565
G P G G G G+ P E+ P R +G G+ L NG+ +
Sbjct: 779 PGTP-GNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR------ 831
Query: 566 AQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSS--PANPS---- 619
+ + P G P +P G S P + + G + P+ P NP
Sbjct: 832 -RGKTGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQ-GEMGPLGQRGYPGNPGILGP 884
Query: 620 -SEESQL-----PGPLGPSAFFHPPTHPQETGSP-FPSPEPPHSLPTHYQPEPAKAFPFP 672
E+ + PG +GP P P + GSP P + P + K P P
Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944
Query: 673 AD-----GLGAEGAFQCLEETPFPHEGPEV----GRGGLQGFP-RAPPPYPTHHFSLSS- 721
++ G E + P V G GL+G P A PP P +
Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004
Query: 722 ----------ASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPG-- 769
S+ + + + F GL G + PG
Sbjct: 1005 PGEPGLRGIPGSMGNMGM-----PGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059
Query: 770 ---PPGLPSPPAAPRVPAD-AHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPF 825
PG P P P +P D G + G A EG + LP
Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----- 1114
Query: 826 PLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPL 885
P P DL + L L + G P P G RG +
Sbjct: 1115 PGPHGDLGFKGIKGL--LGPPGIRGPPGLPGFP----------GSPGPMGIRGDQGRDGI 1162
Query: 886 KSKAGVTPES--KAPPPLPAATPDPQTPRPGDRGCPA-RGRP-KTRSLGLAPTEADAPSQ 941
AG E+ PP P P Q + GDRG P G P + ++G A +
Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIE 1221
Query: 942 GRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL----GERPPPRPRRP 997
G G + + G GS G G G+ G P P+ P
Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP 1281
Query: 998 -----------RTQAPGSRADPAPR-VPRAAALP----EETRSSRRRRLPPRKDPRKRKA 1041
R APG+ P PR P P E+ + P P K
Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGPKG 1340
Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPRGP-------GFRGRRGRGEKRK 1094
G G LKI+ E +P P GP G RG+ G+ K
Sbjct: 1341 PPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPG 1400
Query: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGS 1133
T GP ++ K K AG DG P + G S
Sbjct: 1401 ----TPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDS 1435
Score = 69.3 bits (168), Expect = 7e-11
Identities = 200/845 (23%), Positives = 263/845 (31%), Gaps = 154/845 (18%)
Query: 477 PQSAPLPWPQVLPTARPSPH-GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPR---- 531
PQ LP VL A P+ G + G + + G +G G G +PG +
Sbjct: 9 PQVLLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPG-SPGQKGFTG 67
Query: 532 -EKLPAVRSSQG--GSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASP 588
E LP + +G G P L G+ P F G +P T V G S
Sbjct: 68 PEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSG 127
Query: 589 SESP-----LPSPATNTAGSTCSSLSPMSSSPANPSSEESQ------LPGPLGPSAFFHP 637
S+ LP + L +PA E LPG GP P
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187
Query: 638 PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEV 697
P P G P P F FP +G G + E H+G E
Sbjct: 188 PGFPGPVG----------------PPGPPGFFGFPG-AMGPRGPKGHMGERVIGHKG-ER 229
Query: 698 GRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLL 757
G GL G P PP V++T D N + L
Sbjct: 230 GVKGLTG-PPGPPG----------------TVIVTLTGPD-NRTDL-------------- 257
Query: 758 ARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGFL 817
+ + G + + G PG P P P + G GD +GK
Sbjct: 258 -KGEKGDKGAMGEPGPPGPSGLPGESYGSEKG---------APGDPGLQGK--------- 298
Query: 818 PSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFIDVFADEEPSGPR 877
P P P S+ ++ + L+ E +G++ Q D P G R
Sbjct: 299 PGKDGVP-GFPGSE-GVKGNRGFPGLMGE--DGIKGQK-------------GDIGPPGFR 341
Query: 878 GPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPR--PGDRGCPARGRPKTRSLGLAPTE 935
GP+ + + G E PP P PQ P PG G P RP R G
Sbjct: 342 GPTEYYDTYQEKG--DEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR--GAPGWP 397
Query: 936 ADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPP--- 992
S+G + R GK + + G+ +GS G + G D + + PP
Sbjct: 398 GLKGSKGERGRPGKDA------MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451
Query: 993 -------RPRRPRTQA----PGSRADPAPRVPRAAALPEETRSSRRRRLPPRKDPRKRKA 1041
P P PG P +P LP + +P R+ K
Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 1042 RGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP-----PRGPGFRGRRGRGEKRKEV 1096
G+ G + + E E QP P PG RG+ GR + +
Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGR-KGLDGI 570
Query: 1097 ELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAA 1156
T G + K A E G G P +P PG P P GP E G
Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG--EPGLQG 628
Query: 1157 REGGPKCADRPSVA-PKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTE 1215
+G P P A P+ L V T P P P P +
Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVST---------PVPGPPGPPGPPGHPGPQGPPGIPGSL 679
Query: 1216 ALRSPPAACA--GEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSL 1273
P GE G PG+ P PP + D G P GSL G PG L
Sbjct: 680 GKCGDPGLPGPDGEPGI-PGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737
Query: 1274 LGGPG 1278
G G
Sbjct: 738 PGAKG 742
Score = 67.4 bits (163), Expect = 3e-10
Identities = 285/1227 (23%), Positives = 374/1227 (30%), Gaps = 204/1227 (16%)
Query: 1682 AEGDSRPPQDVCLPEPS--KQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESEDSLRL 1739
A G+ PP LP S + G D G K D FP E R
Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP-------GSEGVKGNRG 318
Query: 1740 LPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASP 1799
P G + E G Q +G P F P + +G P P G
Sbjct: 319 FP-----GLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-----PPGPRG 366
Query: 1800 SHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPA--GASSLTAPRGREAWLVPVPSPACVS 1857
+ QG S G G P + RPG G P G+ G++A P SP C
Sbjct: 367 ARGPQGPS-GPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP-GSPGCAG 424
Query: 1858 NTHPSRRSQDPALSPP------------------IRQLQLPGPGVAKSKDGILGLQELTP 1899
+ P PP + +PG K + G+L Q P
Sbjct: 425 S--PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ--CP 480
Query: 1900 AAQSPPRV-NPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLL 1958
PP + GL G G+ +GSPG T LP G A G GL
Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP---GAQGDPGLK 537
Query: 1959 GQAEKTQGQGTANQLQPENGVS-PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAA 2017
G+ +T LQPE V PG + G T G L KG A
Sbjct: 538 GEKGET--------LQPEGQVGVPGDPGLRGQPGRKGLDGIPG-TPGVKGLPGPKGELAL 588
Query: 2018 MSLQEEAEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAP 2077
+ + P P SP A +G G P+ PGL G P
Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPA-------GPAGPPGYGPQ--GEPGLQGTQGVPGAPGPP 639
Query: 2078 SV----GDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPG 2133
G+L+ P P P GP P P G LG P P G
Sbjct: 640 GEAGPRGELSVSTPVPGP----PGPPGPPGHPGP-QGPPGIPGSLG--KCGDPGLPGPDG 692
Query: 2134 PQQLLACSPAWAPLEEAD-GVQATTDT----GAEDSPVAP--PSLTTSPCDPKEALAGCL 2186
+ P + D G T + G P P P L + +P A+ G
Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-- 750
Query: 2187 LQGEGS---PLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSP 2243
G G+ P E +S G + TP + L P R + P P
Sbjct: 751 --GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGP 805
Query: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAG-RGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302
P P A GL+ G + Q G RG GP +G P DR + S
Sbjct: 806 PGRCIEGPRGAQGLPGLN----GLKGQQGRRGKTGP----KGDPGIPGLDRSGFPGETGS 857
Query: 2303 PSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSK--EPEDPGTPETGRS 2360
P G P P L G D + G G P +PGTP G+
Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP--GQR 915
Query: 2361 GATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS 2420
G+ +P V G+ P + +P + +G+P
Sbjct: 916 GSPGIPGVK--------GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP--------GL 959
Query: 2421 RGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPA 2480
+G+ P N R PG+ K K P P P P
Sbjct: 960 KGFAGNPGEKGN---------------------RGVPGMPGLKGLKGLPGPAGPPGPRGD 998
Query: 2481 ALPAQQPLEPLAQKCQPPRKKSHRVSGKERPNHSRGDPSHVTQP--PPAQGSKEVLRAPG 2538
P EP + P + + G + + G P +P P G + PG
Sbjct: 999 LGSTGNPGEP-GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057
Query: 2539 SPHSQQLHPPSPT-----EHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593
+ PP PT ++ K +P P L P E G
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP----PGHLGPAGPEGAPGSPGSPGLPG 1113
Query: 2594 DSPSHSEGKSNKKRGKLRGRRLREESILP----------VSADVISDGRGSRPSPA---- 2639
H + +G L +R LP + D GR P PA
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD---QGRDGIPGPAGEKG 1170
Query: 2640 -MASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPG 2698
A P G P A G + R A PG + G +A G TG + PG
Sbjct: 1171 ETGLLRAPP----GPRGNPGAQGAKGDRGAPGFPG-LPGRKGAMGDAGPRGPTGIEGFPG 1225
Query: 2699 DRMLCPGRMDGAALGEQPTGQKGA-SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRS 2757
L + G P G +G+ A G GP + +G+ + GS +
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS-----MGHPGPKG 1280
Query: 2758 EEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP------DNPDTQGGVQGPEGPTP 2811
G + PP G LG P T P QG P NP G + GP GP
Sbjct: 1281 PPGTAGDMGPP-GRLGAPGTPGLPGPRGDPG-FQGFPGVKGEKGNPGFLGSI-GPPGPI- 1336
Query: 2812 DASGSSAKDPPSLFDDEVSFSQLFPPG 2838
K PP + D + + PG
Sbjct: 1337 -----GPKGPPGVRGDPGTLKIISLPG 1358
Score = 65.1 bits (157), Expect = 1e-09
Identities = 176/713 (24%), Positives = 227/713 (31%), Gaps = 137/713 (19%)
Query: 28 GHPSQP-PLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSST 86
G P QP P + P R +G R A G L Q R+ + G P + G S
Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851
Query: 87 PGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQ 146
PG+ GSP P + + + G P ILG P ++
Sbjct: 852 PGETGSPGIPGHQGEMGPLGQ-----RGYPGNPGILG-------PPGEDGVIGMMGFPGA 899
Query: 147 LPEVDTPQGPGT----GAPLRPGLPRTEAQPAAE-ELGFHRCFQEPPSSFTSTNYTSPSA 201
+ P PGT G+P PG+ P A+ E G S + P
Sbjct: 900 IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL 959
Query: 202 TPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKG 261
PG +RG P PG G P A P + G EP +G
Sbjct: 960 KGFAGNPGEKGNRGV-PGMPG------LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRG 1012
Query: 262 --------SRPGGSPRGVSFQFP-------FPALHG-----------ASTKPFPADVAGH 295
PG + + FP P +HG T+P P G
Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGD 1072
Query: 296 AFTNGPL----VFAFHQPQG----AWPEEAVGTGPAYPLPTQPAPSPLPCYQG-----QP 342
G + P G A PE A G+ + LP +P P ++G P
Sbjct: 1073 PGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP 1132
Query: 343 GGLNRHSDLSGALSSPG--------AAHSAPRPFSDSLHKSLTKIL--PERPPSAQDGLG 392
G+ L G SPG P P + L + P P AQ G
Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192
Query: 393 STRGPPSSLPQRHFPGQAYRASGV-DTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTP 451
RG P FPG R + D P P PGPP LP P P
Sbjct: 1193 D-RGAPG------FPGLPGRKGAMGDAGPRGPTGIEGFPGPP--GLPGAIIPGQTGNRGP 1243
Query: 452 PGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGP 511
PG + SPG AP P P P G ++ G
Sbjct: 1244 PG------------SRGSPG--------APGP---------PGPPGSHVI--------GI 1266
Query: 512 EWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVS 571
+ GS G G G + P R G+P L G DPG Q F GV + +
Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG--DPGFQG-FPGVKGEKGN 1323
Query: 572 PHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSE-ESQLPGP-- 628
P S+ PP +G P T S S P +P P + E PGP
Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP-PGTPGEPGMQGEPGPPGPPG 1382
Query: 629 -LGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEG 680
LGP P + G+P P+ E + + +K P PA G G
Sbjct: 1383 NLGPCGPRGKPGKDGKPGTPGPAGEKGN--------KGSKGEPGPAGSDGLPG 1427
Score = 58.9 bits (141), Expect = 9e-08
Identities = 116/476 (24%), Positives = 150/476 (31%), Gaps = 78/476 (16%)
Query: 3429 GAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVA 3488
G PG+K +P + +PG A PG PRG P L + +
Sbjct: 964 GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG-----PRGDLGSTGNPGEPGLRGIPGSMG 1018
Query: 3489 ----PST-----TKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRG 3539
P + T G+P RP P H ++G + + E P P P G
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPG-PPGPTGDPGLPG 1077
Query: 3540 DCALDGALERPENEASPGSPGPLLQQALPLGASLP-RPGARG----QDAEGKRAPLVFSG 3594
D G + +P G GP P LP +PG G + +G P G
Sbjct: 1078 DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG 1137
Query: 3595 KRRAPGARGRCAPDHFQEDHLLQ-----KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQ 3649
PG G P + D ++ + + + GPRG G Q
Sbjct: 1138 PPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN---------PGAQ 1188
Query: 3650 SSSKDRSAASTPS----KALKFPVHPRKAVGSLA-------PGELARGTENGMKPATPKA 3698
+ DR A P K PR G PG + G P +
Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248
Query: 3699 KPG-PSSQGS-GSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARA 3756
PG P G GS G K GS P P P + P R
Sbjct: 1249 SPGAPGPPGPPGSHVIGIKGDKGSMGHPG--------------PKGPPGTAGDMGPPGRL 1294
Query: 3757 QAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKP 3816
A P G GP G P +G K +KG PG +GS G P P P
Sbjct: 1295 GA------PGTPGLPGPRGD--PGFQGFPGVKGEKGN-PG-----FLGSIG--PPGPIGP 1338
Query: 3817 PRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
P + P L P S P P + EPG LG P+G+P
Sbjct: 1339 KGPPGVRGDPG-TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393
Score = 46.2 bits (108), Expect = 6e-04
Identities = 119/452 (26%), Positives = 148/452 (32%), Gaps = 83/452 (18%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG+PGQK LP + PG P GS + LP
Sbjct: 57 PGSPGQKGFTGPEGLPGPQGPKGFPG--------LPGLTGSKGVRGISGLPGF------- 101
Query: 3488 APSTTKGWPETLERPVDPVTHPIRGCELPSNHQECP--PPSLS----PFPAALADGRGDC 3541
S + G P T + GC Q P P +L P A L +G
Sbjct: 102 --SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159
Query: 3542 AL--DGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAP 3599
A D L+ + PG+PGP Q LP P P G P F G P
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGP-------VGPPGPPGFFG---FP 206
Query: 3600 GARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKP---AGCQSSSKDRS 3656
GA G P + ++ + E + GP GT + T P + D+
Sbjct: 207 GAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIV-TLTGPDNRTDLKGEKGDKG 265
Query: 3657 AASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG-------PSSQGS 3707
A P P P S PGE + G+E G P P + KPG P S+G
Sbjct: 266 AMGEPG-----PPGP-----SGLPGE-SYGSEKG-APGDPGLQGKPGKDGVPGFPGSEGV 313
Query: 3708 GSPR--PGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765
R PG G + Q G + P + + E P GP
Sbjct: 314 KGNRGFPGLMGEDGIKGQ--KGDIGPPGFRGPTEYYDTYQEKGDEGTPG-------PPGP 364
Query: 3766 REA-GEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824
R A G QGP G G SS +G P S G GR P +P
Sbjct: 365 RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAG 424
Query: 3825 TPSRVLPTKPKPNSQNKPRPPPS-EQRKAEPG 3855
+P LP P P P PP RK PG
Sbjct: 425 SPG--LPGSPGP-----PGPPGDIVFRKGPPG 449
Score = 44.3 bits (103), Expect = 0.002
Identities = 115/447 (25%), Positives = 136/447 (30%), Gaps = 89/447 (19%)
Query: 3414 RGGRQPFAFRG-VRRPGAPGQKARALEGTLP--SKRRRVAMPGSAPGPGEDRPPPRGSSP 3470
+G R F G RPG PG + P S+ R PG PG P G
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPG--LPGDMGKKG 1083
Query: 3471 ILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP------IRGCELPSNHQECPP 3524
+ + P L P G P + P P H I+G P + P
Sbjct: 1084 EMGQPGPPGHL---GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--P 1138
Query: 3525 PSLSPFPAALADG--RGDCALDG----ALERPEN---------EASPGSPGPLLQQALPL 3569
P L FP + RGD DG A E+ E +PG+ G + P
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198
Query: 3570 GASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMV 3628
LP R GA G G R P G PG G P
Sbjct: 1199 FPGLPGRKGAMGD--AGPRGPTGIEGFPGPPGLPGAIIPGQ------------------T 1238
Query: 3629 SEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAP-GELARGT 3687
GP G+ A P G S S P P G + P G L
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA-- 1296
Query: 3688 ENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSR-- 3745
P TP PGP PG K G + P G L S P P P
Sbjct: 1297 -----PGTP-GLPGPRGDPGFQGFPGVK---GEKGNP--GFLGSIGPPGPIGPKGPPGVR 1345
Query: 3746 -------------SPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792
SP P P + E G GP G+LGP K K
Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQG------EPGPPGPPGNLGPCGPRGKPGKDGKP 1399
Query: 3793 QVPGPARSE-SVGSFGR-APSAPDKPP 3817
PGPA + + GS G P+ D P
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGSDGLP 1426
Score = 40.8 bits (94), Expect = 0.027
Identities = 117/495 (23%), Positives = 146/495 (29%), Gaps = 74/495 (14%)
Query: 3428 PGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEV 3487
PG PG K LP + +A+ G G P SP + + P E
Sbjct: 571 PGTPGVKG------LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP 624
Query: 3488 APSTTKGWPETLERPVDP-------VTHPIRGCELPSNHQECPPPSLSP-FPAALADGRG 3539
T+G P P + V+ P+ G P P P P P +L G
Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL----G 680
Query: 3540 DCALDGALERPENEAS------PGSPGPLLQQALP-LGASLPRPGARGQDAEGKRAPLVF 3592
C D L P+ E PG PGP Q P SL PG G+
Sbjct: 681 KCG-DPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG--------L 731
Query: 3593 SGKRRAPGARGR--CAPDHFQEDHLLQKEKEVSSSH----MVSEGGPRGTFHKGSATKPA 3646
GK PGA+G A E+ S H + G GT P
Sbjct: 732 PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791
Query: 3647 GCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPAT-PKAKPG---- 3701
G P + ++ PR A G PG + G + T PK PG
Sbjct: 792 GDPGQPGPPGEQGPPGRCIE---GPRGAQG--LPGLNGLKGQQGRRGKTGPKGDPGIPGL 846
Query: 3702 --------------PSSQGSGSP--RPGTKTGGGSQPQPAS----GQLQSETATTPAKPS 3741
P QG P + G G P G + A P P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 3742 FPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE----KGESSTKRKKGQVPGP 3797
+P P K P GEQG G+ GP E G+ KG P
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP 966
Query: 3798 ARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHT 3857
+ G G K P P L + P P S PG
Sbjct: 967 GEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSK 1026
Query: 3858 QRKDRLGKAFPQGRP 3872
++ LG GRP
Sbjct: 1027 GKRGTLGFPGRAGRP 1041
Score = 37.7 bits (86), Expect = 0.23
Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 9/115 (7%)
Query: 3176 RGQARRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAK 3235
RGQ R D G+ G+ V L E A +G + GSPG P G G A
Sbjct: 559 RGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAG 614
Query: 3236 KDSPGERAKPRARSTPS-----NPDGAATPDSASATALADAGSPGPPRTTPSPSP 3285
G + +P + T P G A P + + G PGPP P P
Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Score = 35.0 bits (79), Expect = 1.5
Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%)
Query: 3183 LGDLPG-----GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGEAKKD 3237
L LPG G+ G A L S P G A G PG G++GE +
Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK-GEKGETLQP 546
Query: 3238 S--------PGERAKPRARST---PSNPDGAATPDSASATALA----DAGSPGPPRTTPS 3282
PG R +P + P P P AL+ D G PG P + S
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606
Query: 3283 PSPDPWAG-------GEPLLQAT 3298
P P AG GEP LQ T
Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGT 629
Score = 32.3 bits (72), Expect = 9.5
Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 28/116 (24%)
Query: 3205 EPAPKHHRGK--RSAGKAAGSPGDPWGQEGEAKKDS----PGERAKPRARSTPS------ 3252
EP P G S G G+PGDP G +G+ KD PG R P
Sbjct: 269 EPGPPGPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327
Query: 3253 --------NPDGAATPDSASAT--ALADAGSPGPP-----RTTPSPSPDPWAGGEP 3293
P G P T D G+PGPP R PS P G P
Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 90.5 bits (223), Expect = 3e-17
Identities = 262/1076 (24%), Positives = 321/1076 (29%), Gaps = 213/1076 (19%)
Query: 6 PRGAP-PPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQ 64
PRG P P G L P+ PG P + D P + G + G P AQ
Sbjct: 671 PRGLPGEPGPRGLLGPKGPPGPPGPPGVTGM-DGQPGPKGNVGPQGEPGPPGQQGNPGAQ 729
Query: 65 PRQARDGELKPPSLRGQAPSSTPGKRGSP-----------QTPPGRSPLQAPSRLAGRAE 113
G + PP +G P PG G P + PPG Q P G
Sbjct: 730 GLPGPQGAIGPPGEKG--PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPI- 786
Query: 114 GSPPQRYILGIASSR-TKPTLDETPENPQLEAAQLPEVDTPQG-PGTGAPLRPGLPRTEA 171
G P R + G R K T E E+ P G G + P PR E
Sbjct: 787 GYPGPRGVKGADGIRGLKGTKGEKGED------GFPGFKGDMGIKGDRGEIGPPGPRGED 840
Query: 172 QPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQA-S 230
P + P+ P P P + + P PG YP Q
Sbjct: 841 GPEGPK-----------------GRGGPNGDPGPLGPPGEKGKLGVPGLPG-YPGRQGPK 882
Query: 231 GADSWPPAAENSFPGANF--------GVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHG 282
G+ +P FPGAN G P + P G R PRG++ + P G
Sbjct: 883 GSIGFP-----GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGK---PGPKG 934
Query: 283 ASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQP 342
S PA G NGP Q +P GP P P P LP + GQ
Sbjct: 935 NSGGDGPAGPPGERGPNGP------QGPTGFP------GPKGP-PGPPGKDGLPGHPGQR 981
Query: 343 G--GLNRHSDLSG--ALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQ--DGLGSTRG 396
G G + G + P P + H P PP Q GL G
Sbjct: 982 GETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG-----PPGPPGEQGLPGLAGKEG 1036
Query: 397 P-----PSSLPQRHFPGQAYRASGVDTSPGPPDT-----ELAAPGPP-PARLPQLWDPTA 445
P+ LP + P G PGP PGPP PA P P
Sbjct: 1037 TKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAG 1096
Query: 446 APYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLP 505
A GP+ G P P P P G++ LP
Sbjct: 1097 A------AGPIGIPGRPGPQGPPGPAGEKGAPGEKG-------PQGPAGRDGLQGPVGLP 1143
Query: 506 FPAG--GPEWQGGSQGALGTAGKTPGPREK----LPAVRSSQG--GSPALFTYNGMTDPG 557
PAG GP + G +G +G G+ +K P QG G P +G P
Sbjct: 1144 GPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPR 1203
Query: 558 AQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPAN 617
Q FG + P G P PP VG P P G P P
Sbjct: 1204 GQQGLFG-QKGDEGPRGFPG--PPGPVGL--QGLPGPPGEKGETGDVGQMGPPGPPGPRG 1258
Query: 618 PSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLG 677
PS GP GP P E G P + EP LP P K G
Sbjct: 1259 PSGAPG-ADGPQGPPGGIGNPGAVGEKGEPGEAGEP--GLPGEGGPPGPKGERGEKGESG 1315
Query: 678 AEGAFQCLEETPFPHEGPEVGRGGLQGFPRAP-PPYPTHHFSLSSASLDQLDVLLTCRQC 736
GA P + G G GFP P PP D+ D
Sbjct: 1316 PSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD-------- 1367
Query: 737 DRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP-RVPADAHAGLLSHAK 795
+ G SPGP G P P P + AG
Sbjct: 1368 ----------------------DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405
Query: 796 TFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQS 855
G+A EG P +TG + A P P + L G+
Sbjct: 1406 EKGAKGEAGLEG--PPG