Guide to the Human Genome
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Search of human proteins with 18780273

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18780273 collagen, type XXI, alpha 1 precursor [Homo
sapiens]
         (957 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]     1998   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               618   e-177
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   493   e-139
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]        439   e-123
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...   436   e-122
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  431   e-120
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    427   e-119
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     422   e-118
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       419   e-117
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   414   e-115
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   413   e-115
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   410   e-114
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     409   e-114
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   409   e-114
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   392   e-109
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   392   e-109
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   392   e-109
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   392   e-109
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     392   e-109
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        392   e-109
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   391   e-108
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   391   e-108
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   386   e-107
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              385   e-106
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      385   e-106
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      384   e-106
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         381   e-105
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...   380   e-105
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...   380   e-105
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...   379   e-105

>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score = 1998 bits (5175), Expect = 0.0
 Identities = 957/957 (100%), Positives = 957/957 (100%)

Query: 1   MAHYITFLCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWL 60
           MAHYITFLCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWL
Sbjct: 1   MAHYITFLCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWL 60

Query: 61  VNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAI 120
           VNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAI
Sbjct: 61  VNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAI 120

Query: 121 QFALDYLFAKSSRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELR 180
           QFALDYLFAKSSRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELR
Sbjct: 121 QFALDYLFAKSSRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELR 180

Query: 181 AIANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVCPTRIPVAARDERGFDILLGLDVN 240
           AIANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVCPTRIPVAARDERGFDILLGLDVN
Sbjct: 181 AIANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVCPTRIPVAARDERGFDILLGLDVN 240

Query: 241 KKVKKRIQLSPKKIKGYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWDLWRI 300
           KKVKKRIQLSPKKIKGYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWDLWRI
Sbjct: 241 KKVKKRIQLSPKKIKGYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWDLWRI 300

Query: 301 LTIDGRPQIAVTLNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQD 360
           LTIDGRPQIAVTLNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQD
Sbjct: 301 LTIDGRPQIAVTLNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQD 360

Query: 361 VTLYIDDQQIENKPLHPVLGILINGQTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETA 420
           VTLYIDDQQIENKPLHPVLGILINGQTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETA
Sbjct: 361 VTLYIDDQQIENKPLHPVLGILINGQTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETA 420

Query: 421 CEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGY 480
           CEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGY
Sbjct: 421 CEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGY 480

Query: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540
           QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD
Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540

Query: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600
           KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT
Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600

Query: 601 RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660
           RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE
Sbjct: 601 RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660

Query: 661 PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI 720
           PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI
Sbjct: 661 PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI 720

Query: 721 PGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGL 780
           PGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGL
Sbjct: 721 PGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGL 780

Query: 781 DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG 840
           DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG
Sbjct: 781 DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG 840

Query: 841 PRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGP 900
           PRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGP
Sbjct: 841 PRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGP 900

Query: 901 PGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPNY 957
           PGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPNY
Sbjct: 901 PGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPNY 957


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  618 bits (1594), Expect = e-177
 Identities = 380/1003 (37%), Positives = 510/1003 (50%), Gaps = 128/1003 (12%)

Query: 28  RSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVL 87
           R+ C++   DLVF+LD S SVG E+FE V++W+ N+   F++GP   +VGVV+YSD P  
Sbjct: 29  RAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTT 88

Query: 88  EIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSS------RFLTKIAVV 141
              LG + S E + AA   + Y GGNT TG A+++     F+  +      R   ++A++
Sbjct: 89  AFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAIL 148

Query: 142 LTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAIS 201
           LTDG+SQD V DAA AA  + I +FA+GVG   ++ EL  IA++P S +VF+V D+ AI 
Sbjct: 149 LTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKE-ELEEIASEPKSAHVFHVSDFNAID 207

Query: 202 KIREVMKQKLCEESVCPT---------RIPVAARDERGFDILLGLDVNKKVKKRIQLSPK 252
           KIR  ++++LCE  +CP+               ++  GFD++    V + + KR   +  
Sbjct: 208 KIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQS 267

Query: 253 KIKGYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKV---KKIWDLWRILTIDGRPQI 309
               Y       + + T +VFP+GLP  Y FV+T RF+    K+ W +W+++     PQ+
Sbjct: 268 S---YVRMGSFPVVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQV 324

Query: 310 AVTLNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQ 369
           ++ L+G +K + +     +  +  V F   +V  LFD  WH++ L +  Q+V+L+ID   
Sbjct: 325 SIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCAL 384

Query: 370 IENKPLHPVLGILINGQTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGE 429
           ++  P+     I I G+T IGK       + FD+Q++ IYCD      ET C+IP  +G 
Sbjct: 385 VQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIP--SGP 442

Query: 430 CL-------NGPSDVGSTPAP------------CICPPGKPG---------LQGPKGDPG 461
           C          P      P P            C CP G+ G         L GPKGD G
Sbjct: 443 CQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIG 502

Query: 462 LPGNPGYPGQPGQ----------DGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRD 511
             G  G PG  G+           G+ G +G  G PG PG  G +G RG PG  GEPG  
Sbjct: 503 AIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLP 562

Query: 512 GDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEP 571
           G+ G RG  G PGL G PG  G  G +G++G  G    +G KGE+G  GFPG PG  G+ 
Sbjct: 563 GEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG---TRGEKGERGLDGFPGKPGDTGQQ 619

Query: 572 GRHGKDGLMGSPGFKGE---AGSPGAPGQ-------------DGTRGEPGIPGFPGNRGL 615
           GR G  G+ G  G KG+   AG PG PG               G RG  G PG PG RG 
Sbjct: 620 GRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGP 679

Query: 616 MGQKGEIGPPGQQGKKGA------PGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA 669
           +G +G  GPPG QG +G       PG+PGL+G  G PG PG PG  G  G PG+ G  G 
Sbjct: 680 IGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGF 739

Query: 670 SGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGH 729
            G  G PG TG PG+ G  G PG  G KG+ G +GE G+ G+ G  G  G  G  G  G 
Sbjct: 740 PGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE 799

Query: 730 HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFS 789
            G  G  G  G PGVRG  G +GE G  GL G  G +G+ G+ GP GPPGL G       
Sbjct: 800 KGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG------- 852

Query: 790 EQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP-------- 841
                   T  +    P +      +         G PG+ G PG +GP+GP        
Sbjct: 853 --------TTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 904

Query: 842 ----------RGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGP 891
                      G PG PG  G PG  G PG  G  GL+G PG++GE+G +G    GE+G 
Sbjct: 905 QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA--GEEGS 962

Query: 892 PGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           PGP GP G P     G PG PG PGK G  G+PG++G PG PG
Sbjct: 963 PGPVGPRGDP-----GAPGLPGPPGK-GKDGEPGLRGSPGLPG 999



 Score =  422 bits (1086), Expect = e-118
 Identities = 242/539 (44%), Positives = 290/539 (53%), Gaps = 58/539 (10%)

Query: 446  CPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGI---QGARGLP 502
            CPPG PGL G    PG  G+ G PG+PG++G  G +G AG PG+PG PGI   QG++G  
Sbjct: 1117 CPPGPPGLPGL---PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173

Query: 503  GYKGEPGRDGDKGDRGLPGF---------------------PGLHGMPGSKGEMGAKGDK 541
            G  GE G+ GD+G  G+PGF                     PG+ G PG +G  G +G  
Sbjct: 1174 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233

Query: 542  GSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTR 601
            G PG  G++G +G  G  G PG PG AGEPG  G +G  G PGFKG  G  GAP   G R
Sbjct: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAP---GPR 1290

Query: 602  GEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP---GTPGSKGSK 658
            GE G  G PG  GL G+ G+ GP G QG +G  G PG  GS GSPG+P   GTPG KGSK
Sbjct: 1291 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 1350

Query: 659  GEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQ 718
            GE G  G+PG  G +G PG  G  G PG  G+PG  G+ G KG +G+ GI+G KG  G +
Sbjct: 1351 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410

Query: 719  GIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPP 778
            G PG  GI GH G  G  G +G PG  G +            GP GP GQPG PG +G  
Sbjct: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPV------------GPPGPPGQPGFPGLRGE- 1457

Query: 779  GLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP 838
                 P  E   + I++     +  +L  LL         +  S  G PG PGPPG  G 
Sbjct: 1458 ----SPSMETLRRLIQEELGKQLETRLAYLLAQ---MPPAYMKSSQGRPGPPGPPGKDGL 1510

Query: 839  EGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPE 898
             G  G  G PGR   PG  G+ G  G  G KG  G  G+ G+ G G  GE GPPG PG  
Sbjct: 1511 PGRAGPMGEPGR---PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQP 1567

Query: 899  GPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLC--FSVIARRDPFRKGP 955
            G PG +K+G PG PG  G+ G  G PG+ G PGPPG CDPS C  F+ +A R    KGP
Sbjct: 1568 GEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626



 Score =  368 bits (944), Expect = e-101
 Identities = 232/584 (39%), Positives = 277/584 (47%), Gaps = 91/584 (15%)

Query: 423  IPGFNGECLNGPSDVGST----PAPCICPPGKPGLQGPKGDPGLPGN----PGYPGQPGQ 474
            + GF G+    P D G      P+    P G+ G  GP G PG+PG+     G  G+ G 
Sbjct: 606  LDGFPGK----PGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA 661

Query: 475  DGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGE 534
             G  G+QG  G PG  G  G +G  G PG +G  G+ GD G  G+PG  GL G PG  G 
Sbjct: 662  PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGV 721

Query: 535  MGAKGDKGSPGFYGK------------KGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGS 582
             G  G  GSPG  G+             G  G+ G  G PG PG  GEPG  G+DGL G 
Sbjct: 722  PGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK 781

Query: 583  PGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGS 642
            PG +GE G  G  G+ G +GE G+PG PG  G+ G+KG+      QG+KG  G+PGL G 
Sbjct: 782  PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD------QGEKGELGLPGLKGD 835

Query: 643  NGSPGQPGTPGSKGSKGEPGI----QGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKG 698
             G  G+ G  G  G  G   +      MPG  G KGE G  G PGEPG  G PG  G +G
Sbjct: 836  RGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQG 895

Query: 699  DKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGA------IGSKG 752
              G  G KG +G  G  G  G PG  G  G  G  G  G  G PG+RG        G KG
Sbjct: 896  PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKG 955

Query: 753  ESGVDGLMGPAGPKGQPGDPGPQGPP--GLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQ 810
             +G +G  GP GP+G PG PG  GPP  G DG+PG   S           +   L     
Sbjct: 956  AAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG---------LPGPLGTKAA 1006

Query: 811  SGRIRNCDHCL-------SQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRP 863
             G++R  ++C           G+PGIPG PG  G  G  G+ G PG  G P   G  G P
Sbjct: 1007 CGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPP---GDKGSP 1062

Query: 864  GVRGLKGLPGRNGEKGSQGF-GYPGEQGPPGPPG---------------------PEGPP 901
            G RGL G PG  G  G  G  G PGE+GPPG PG                     P GPP
Sbjct: 1063 GSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPP 1122

Query: 902  GI-------SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            G+         +G PG PG  G +G  G+ G  G PGPPGI  P
Sbjct: 1123 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 1166



 Score =  235 bits (600), Expect = 1e-61
 Identities = 154/384 (40%), Positives = 188/384 (48%), Gaps = 60/384 (15%)

Query: 562 PGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGE 621
           P  P P   P   G + +    GF          G+ G  G  G  G PG +G +G  G 
Sbjct: 451 PPPPPPPQRPPTPGSEQI----GFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGP 506

Query: 622 IGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGS 681
           +G PG +G+KG  G+         P   G  G KGS G PG  G  G+ G++GEPG  G 
Sbjct: 507 VGAPGPKGEKGDVGI--------GPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558

Query: 682 PGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGE 741
           PG PG +G+ G QG  G              G  GR G PG   +QG  G KG RGEKGE
Sbjct: 559 PGLPGEVGMRGPQGPPG------------LPGPPGRVGAPG---LQGERGEKGTRGEKGE 603

Query: 742 PGVRGAIGSKGESGVDGLMGP---AGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCT 798
            G+ G  G  G++G  G  GP   AGP+G+ GD GP GPPG+   PG    ++ ++    
Sbjct: 604 RGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGV---PGSVVQQEGLKG--- 657

Query: 799 DVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVG 858
                      + G      H     G+PG PG  GPIGPEG  G PGL G  G  G +G
Sbjct: 658 -----------EQGAPGPRGH----QGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMG 702

Query: 859 VPGRPGVRGLKGLPGRNGEKGSQG----FGYPGE---QGPPGPPGPEGPPGISKEGPPGD 911
            PG PG+ GL+G PG  G  G  G     G PGE    G PGPPGP GPPG  K+GP G 
Sbjct: 703 PPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPG--KDGPNGP 760

Query: 912 PGLPGKDGDHGKPGIQGQPGPPGI 935
           PG PG  G+ G+ G  G PG PG+
Sbjct: 761 PGPPGTKGEPGERGEDGLPGKPGL 784



 Score =  108 bits (269), Expect = 3e-23
 Identities = 77/205 (37%), Positives = 93/205 (45%), Gaps = 55/205 (26%)

Query: 734 GERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFI 793
           GE+GE G  G  G  G KG+ G  G +G  GPKG+ GD G  GP G  G+ G +      
Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-GPFG-QGEKGEK------ 532

Query: 794 RQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGV 853
                                          GS G+PGPPG  G +G RG PG  G  G+
Sbjct: 533 -------------------------------GSLGLPGPPGRDGSKGMRGEPGELGEPGL 561

Query: 854 PGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPG 913
           PG VG+ G  G  GL G PGR G  G QG     E+G  G  G +G  G+         G
Sbjct: 562 PGEVGMRGPQGPPGLPGPPGRVGAPGLQG-----ERGEKGTRGEKGERGLD--------G 608

Query: 914 LPGKDGDHGKPGIQGQPGPPGICDP 938
            PGK GD G+   QG+PGP G+  P
Sbjct: 609 FPGKPGDTGQ---QGRPGPSGVAGP 630



 Score =  104 bits (259), Expect = 4e-22
 Identities = 79/215 (36%), Positives = 90/215 (41%), Gaps = 55/215 (25%)

Query: 765 PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCL--- 821
           P G+ G+ G  GP GL G  G               I A  PV     +    D  +   
Sbjct: 479 PAGEKGEMGVAGPMGLPGPKGD--------------IGAIGPVGAPGPKGEKGDVGIGPF 524

Query: 822 -----SQHGSPGIPGPPGPIGPEGPRGLP------------------GLPGRDGVPGLVG 858
                 + GS G+PGPPG  G +G RG P                  G PG  G PG VG
Sbjct: 525 GQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVG 584

Query: 859 VPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGPPG----ISKEGPPG 910
            PG  G RG KG  G  GE+G  GF    G  G+QG PGP G  GP G    +   GPPG
Sbjct: 585 APGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPG 644

Query: 911 DP-------GLPGKDGDHGKPGIQGQPGPPGICDP 938
            P       GL G+ G  G  G QG PGPPG   P
Sbjct: 645 VPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGP 679


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score =  493 bits (1270), Expect = e-139
 Identities = 320/898 (35%), Positives = 421/898 (46%), Gaps = 177/898 (19%)

Query: 216 VCPTRIPVAARDERGFDILLGLDVNKKVKKR----IQLSPKKIKGYEVTSKVDLSELTSN 271
           +CP +I +   D  GFD++    V+K   +R    +  S      Y++ + VD    T N
Sbjct: 43  LCP-KIRIGQDDLPGFDLISQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRN 101

Query: 272 VFPEGLPPSYVFVSTQRFK---VKKIWDLWRILTIDGRPQIAVTLNGVDKILLFTTTSVI 328
           ++P GLP  Y F++T R     +KK W++W+I    G+ Q+ + +NG  + ++F+   + 
Sbjct: 102 LYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLD 161

Query: 329 NGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIENKPLHPVLGILINGQTQ 388
              Q   F+N  + +LFD  WH+I + V     TL++D  +IE+ P+ P   I I+G   
Sbjct: 162 GSLQTAAFSN--LSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAV 219

Query: 389 IGKYSGKEE-TVQFDVQKLRIYCDPEQNNRETACEIPGFNGECLNGPSDVGSTPAPCICP 447
           +GK +   + +V F++Q + I+CDP +  RET  E+P               TP+     
Sbjct: 220 LGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPA------------RITPSQTTDE 267

Query: 448 PGKPGLQGPKGDPGLPGNPGYPG------QPGQDGKPGYQGIAGTPGVPGSPGIQGARGL 501
            G PG QGP G PG PG PG  G        G  G PG  G  G PG PG PG  GA GL
Sbjct: 268 RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327

Query: 502 PGYKGEPGRDGDKGDRGLPGFPGLHGMPGS--------------KGEMGAKGDKGSPGFY 547
            G  G PG  G KG +G PG PG  G PG                GE+G  G  G PG  
Sbjct: 328 TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 387

Query: 548 GKKGAKG---------------------EKGNAGFPGLP---------GPAGEPGRHGKD 577
           G  G  G                       G +G+PGLP         G  GEPGR G  
Sbjct: 388 GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 447

Query: 578 GLMGSPGFKGEAGSPGAPGQDGTR------------------GEP---GIPGFPGNRGLM 616
           G  G  G  GE G+ G PG  G R                  GEP   G+PG PG++G  
Sbjct: 448 GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR 507

Query: 617 GQKGEIGPPGQQGKKGAPGMPGL---------------------MGSNGSPGQPGTPGSK 655
           G  GE GP G +G +GA G+PGL                      G+ G PG+PG PG  
Sbjct: 508 GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA 567

Query: 656 GSKGEPGIQGMPGASGLKGEPGATGSPGEPGYM---GLPGIQGKKGDKGNQGEKGIQGQK 712
           G +G PG+ G+PGA G+ GE G+TG+PG+PG M   G PG QG  G+ G +G +G+ G +
Sbjct: 568 GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSR 627

Query: 713 GENGRQGIP---------------------------------------GQQGIQGHHGAK 733
           GE G  G P                                       G+QG  G  G  
Sbjct: 628 GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEA 687

Query: 734 GERGE---------------KGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPP 778
           GERGE                GEPG+RG  GS+G  GV+G  GP GP+G  G+ G  G P
Sbjct: 688 GERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP 747

Query: 779 GLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP 838
           G+ G PGR  ++Q I+QVC  VI+     +  S  ++  D      G PG PGPPGP GP
Sbjct: 748 GVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS--LKRPDS--GATGLPGRPGPPGPPGP 803

Query: 839 EGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPE 898
            G  G PG  G  G+PG+ G PG  G+RG KG  G  GE+G  G G  G  G  G PG  
Sbjct: 804 PGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDP 863

Query: 899 GPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPN 956
           GP    + G  G+ G PG  G  G PG  G PG PG C+P+ C ++ A +  F KGP+
Sbjct: 864 GPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC-TMQAGQRAFNKGPD 920



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 53/135 (39%), Positives = 60/135 (44%), Gaps = 22/135 (16%)

Query: 455 GPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGD- 513
           G  G PG PG PG PG PG++G PG  GI G PG+ G PG  G RG  G  GE G  G  
Sbjct: 787 GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPP 846

Query: 514 -KGDRGLPGFPGLHGMPG--SKGEMGAKGDK------------------GSPGFYGKKGA 552
            +G  GLPG  GL G PG  S G  G  G++                  G PGF      
Sbjct: 847 GRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906

Query: 553 KGEKGNAGFPGLPGP 567
             + G   F   P P
Sbjct: 907 TMQAGQRAFNKGPDP 921


>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
          Length = 1142

 Score =  439 bits (1129), Expect = e-123
 Identities = 286/792 (36%), Positives = 376/792 (47%), Gaps = 136/792 (17%)

Query: 269 TSNVFPEGLPPSYVFVSTQRFK---VKKIWDLWRILTIDGRPQIAVTLNGVDKILLFTTT 325
           T  +FP+GLP  Y   +  R +    K+ W LW++L     PQI++ ++G  K++ F   
Sbjct: 88  TIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLNQQNIPQISIVVDGGKKVVEFMFQ 147

Query: 326 SVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIENKPLHPVLGILING 385
           +         F N +++ LFD  WH++ + +  Q ++LY+D   I  +       +  +G
Sbjct: 148 ATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVISLYMDCNLIARRQTDEKDTVDFHG 207

Query: 386 QTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGECLNGPSDVGST----- 440
           +T I   +   + V  ++ +L+IYC      +ET CEI        +G  ++ S+     
Sbjct: 208 RTVIATRASDGKPVDIELHQLKIYCSANLIAQETCCEISDTKCPEQDGFGNIASSWVTAH 267

Query: 441 --------PAP------CICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGT 486
                   PA       C C P K       G+ GLPG PG PGQ G  G+PG  G+ G 
Sbjct: 268 ASKMSSYLPAKQELKDQCQCIPNK-------GEAGLPGAPGSPGQKGHKGEPGENGLHGA 320

Query: 487 PGVPGSPGIQGARGLPGYKGEPGRDGDKGD---------RGLPGFPGLHGMPGSKGE--- 534
           PG PG  G QG  G  G  GE G  G+KGD          GL G  G HG PG KGE   
Sbjct: 321 PGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGD 380

Query: 535 ------------MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGS 582
                       +G +G +G PG  G++G +G+ G  G PG PGP G PG  G    +G 
Sbjct: 381 TGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGG 440

Query: 583 PGFKGEAGSP--GAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLM 640
              K   G+    A G  G +GE G+PGFPG+ G  GQKGE G P  +G+KG  G PG++
Sbjct: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVI 500

Query: 641 GSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDK 700
           GS G  G+PG PG  G  G PG++G  G++G  G  G  G  G PG  G+PG QG KG+K
Sbjct: 501 GSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEK 560

Query: 701 GNQ----GEKGIQGQKGENGRQG--IPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGES 754
           G+     G  G+ G KGE G  G  +PG+ G+ G+ GA G RG KGE G+ G  GS G+ 
Sbjct: 561 GDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDI 620

Query: 755 GVDGL--------MGPA------GPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDV 800
           G  G+         GPA      GP+G PG PG  G PG DG PGR+  +  +     D 
Sbjct: 621 GPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRD-GKPGLPGPPGDP 679

Query: 801 IRAQLPVLLQSGRIRN--CDHC-------------------------------LSQHGSP 827
           I   LP+L   G +    C +C                               +   G P
Sbjct: 680 I--ALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPP 737

Query: 828 GIPGPPGPIGPEGPRGLPGLPGR---DGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF- 883
           GIPG  GP G +G RG PG+PG    +G+ G+ G+PG PG  G  GL GR G  G  G  
Sbjct: 738 GIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAK 797

Query: 884 GYPGEQGPPGPPGPEGPPGI---------------------SKEGPPGDPGLPGKDGDHG 922
           G  G  GPPG PGP GPPGI                     S  GPPG PG  G  G  G
Sbjct: 798 GEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVG 857

Query: 923 KPGIQGQPGPPG 934
           +PG  G PG  G
Sbjct: 858 EPGAMGLPGLEG 869



 Score =  346 bits (888), Expect = 5e-95
 Identities = 231/580 (39%), Positives = 276/580 (47%), Gaps = 122/580 (21%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPG------LPGNPGYPGQPGQDG 476
            +PG +G     P D+G      I  PG+ G QGP G+PG      LPG PG PG PG DG
Sbjct: 610  LPGVHGS----PGDIGPQG---IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDG 662

Query: 477  KPGYQGIAGTPGVPGSP-------------------------GIQGARGLPGYKGEPG-- 509
             PG  G  G PG PG P                         G++  +G  G  GEPG  
Sbjct: 663  VPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKY 722

Query: 510  ----RDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLP 565
                R GD G RG PG PG  G  GSKGE      +G PG  G+KG +G +G  G PG P
Sbjct: 723  DSMARKGDIGPRGPPGIPGREGPKGSKGE------RGYPGIPGEKGDEGLQGIPGIPGAP 776

Query: 566  GPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGN--RGLMGQKGEI- 622
            GP G PG  G+ G  G  G KGE GS G PG+ G  G PGIP    N    L   KG + 
Sbjct: 777  GPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVN 836

Query: 623  -----GPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
                 GPPG  G KG PG  G  G+ G PG  G PG KG +G  G    PG +G+ G+PG
Sbjct: 837  VPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG---PPGIAGMSGKPG 893

Query: 678  ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGH---HGAKG 734
            A G PG PG    PG +G  GD G  G +G  G+ G NG+ GIPG QGI G     G KG
Sbjct: 894  APGPPGVPGE---PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKG 950

Query: 735  ERGEKGEPGVRGAIGSKGESGVDGL------MGPAGPKGQPGDPGPQGPPGLDGKPGR-- 786
            ERG++G PG RG+ G +G+ G+ G+      MGP G KG  G PG QGPPG  G PG   
Sbjct: 951  ERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPA 1010

Query: 787  -----EFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP 841
                 E  +++I Q    +   ++ V L   ++                  P  +     
Sbjct: 1011 DAVSFEEIKKYINQEVLRIFEERMAVFLSQLKL------------------PAAMLAAQA 1052

Query: 842  RGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPP 901
             G PG PG+DG+PG    PG PG +G +G  G  GE G             G PG  G P
Sbjct: 1053 YGRPGPPGKDGLPG---PPGDPGPQGYRGQKGERGEPGI------------GLPGSPGLP 1097

Query: 902  GISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLC 941
            G S  G PG PG PG          QG PGP G C+P  C
Sbjct: 1098 GTSALGLPGSPGAPGP---------QGPPGPSGRCNPEDC 1128



 Score =  261 bits (667), Expect = 2e-69
 Identities = 168/411 (40%), Positives = 194/411 (47%), Gaps = 78/411 (18%)

Query: 553 KGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGN 612
           KGE G  G PG PG  G  G  G++GL G+PGF G+ G  G  G  G  GE G  G  G+
Sbjct: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350

Query: 613 RGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGL 672
             L G  GE G  G  G  G PG  G  G  G PG P  PGS G +G  G  G  G  G 
Sbjct: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410

Query: 673 KGEPGATGSPGEPGYMGLPGIQG---------KKGDKGNQGEK--GIQGQKGENGRQGIP 721
           +G+ G  G PG PG  G PGIQG          K +KGN   +  G++G KGE G  G P
Sbjct: 411 RGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFP 470

Query: 722 GQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLD 781
           G  G       KG++GE GEP  +G  G +GE GV   +G  G KG+PGDPGP   PGL 
Sbjct: 471 GSVG------PKGQKGEPGEPFTKGEKGDRGEPGV---IGSQGVKGEPGDPGP---PGLI 518

Query: 782 GKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP 841
           G PG +                                   Q GS G  GP GP G  G 
Sbjct: 519 GSPGLK----------------------------------GQQGSAGSMGPRGPPGDVGL 544

Query: 842 RGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGE---QGPPGPPGPE 898
            G  G+PG+ G+ G  G PG  G+ G  GLPG  GE G  G   PGE    G PG PGP 
Sbjct: 545 PGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPR 602

Query: 899 GP------PGISKEGPPGD--------PGLPGKDGDHGKPGIQGQPGPPGI 935
           GP      PG+   G PGD        PG  G  G  G+PGIQG  G PG+
Sbjct: 603 GPKGERGLPGV--HGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGL 651


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score =  436 bits (1122), Expect = e-122
 Identities = 239/525 (45%), Positives = 294/525 (56%), Gaps = 17/525 (3%)

Query: 438 GSTPAPCICPPGK---PGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPG 494
           G    P  CPPG+   PGL G +G  G  G  G PG+ G  G+ G QG  G  G  G PG
Sbjct: 164 GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 223

Query: 495 IQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKG 554
            QG RG+ G  G+ G   +KG RGL G PG  G+PG+ G+   +G +G PG  G KG +G
Sbjct: 224 AQGLRGITGIVGDKG---EKGARGLDGEPGPQGLPGAPGD---QGQRGPPGEAGPKGDRG 277

Query: 555 EKGNAGFPGLPGPAGE---PGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611
            +G  G PGLPGP G+   PG  G+DG+ G PG KGE G PG PG  G +G PG+PG PG
Sbjct: 278 AEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG 337

Query: 612 NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASG 671
            +G+ G+KG  G PG+ G+ G  G PG  G  G  G  G  G  GS+GE G  G PG  G
Sbjct: 338 AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPG 397

Query: 672 LKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG 731
             G  G+ G PG PG  GLPG++G +G  G  G KG QG  GE G  G  G+ G  G  G
Sbjct: 398 KLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPG 457

Query: 732 AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQ 791
            KG  G  GEPG+RG  GS+G  GV+G  GP GP+G  G+ G  G PG+ G PGR  ++Q
Sbjct: 458 PKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQ 517

Query: 792 FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRD 851
            I+QVC  VI+     +  S  ++  D      G PG PGPPGP GP G  G PG  G  
Sbjct: 518 HIKQVCMRVIQEHFAEMAAS--LKRPDS--GATGLPGRPGPPGPPGPPGENGFPGQMGIR 573

Query: 852 GVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGD 911
           G+PG+ G PG  G+RG KG  G  GE+G  G G  G  G  G PG  GP    + G  G+
Sbjct: 574 GLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGE 633

Query: 912 PGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPN 956
            G PG  G  G PG  G PG PG C+P+ C ++ A +  F KGP+
Sbjct: 634 RGPPGVAGIPGVPGPPGPPGLPGFCEPASC-TMQAGQRAFNKGPD 677



 Score =  352 bits (904), Expect = 7e-97
 Identities = 214/498 (42%), Positives = 251/498 (50%), Gaps = 68/498 (13%)

Query: 474 QDGKPGYQGIAGTPGVPGSPGI---------QGARGLPGYKGEPGRDGDKGDRGLPGFPG 524
           Q G PG QG  G PG PG PGI         +G  G PG  GEPG+ G  G  G PG  G
Sbjct: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83

Query: 525 LHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPG 584
           L G  GS G +G+KG KG PG  G +G  G +G  G PG PG AG PG  G+ G +G PG
Sbjct: 84  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPG 142

Query: 585 FKGEAGSPGAPGQDGT---------------RGEPGIPGFPGNRGLMGQKGEIGPPGQQG 629
            +G  G PG PG  GT                G  G PG PG RG  G KGEIG PG+QG
Sbjct: 143 RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG 202

Query: 630 KKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEP---G 686
            KG  G  G +G  G+ G PG  G +G  G  G +G  GA GL GEPG  G PG P   G
Sbjct: 203 HKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQG 262

Query: 687 YMGLPGIQGKKGDKGNQGEKGI---QGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPG 743
             G PG  G KGD+G +G +GI    G KG+ G  G+ G+ GI G  G KGE G+ G PG
Sbjct: 263 QRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPG 322

Query: 744 VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRA 803
             G  G  G  G+ G  G AG KG  G PG  G  G  GKPG++     +          
Sbjct: 323 DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV---------- 372

Query: 804 QLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRP 863
                                G  G+PG  G +GP G  GLPG  G  G PGL G+PG P
Sbjct: 373 ------------------GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP 414

Query: 864 GVRGLK------GLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPG 916
           G+ G+K      G PG  GE+G+ G  G  GE+G  G  G  GP G    G PG+PGL G
Sbjct: 415 GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKG--SAGNPGEPGLRG 472

Query: 917 KDGDHGKPGIQGQPGPPG 934
            +G  G PG++G  GPPG
Sbjct: 473 PEGSRGLPGVEGPRGPPG 490



 Score =  271 bits (692), Expect = 3e-72
 Identities = 172/410 (41%), Positives = 197/410 (48%), Gaps = 78/410 (19%)

Query: 586 KGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN-- 643
           +G  G  G PG  G  G PGI G  G+RG  G  G  GP G+ GK GAPG PG  G++  
Sbjct: 25  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84

Query: 644 -GSPGQPGTPGSKGSKGEPGIQGM--------------PGASGLKGE---------PGAT 679
            G  G PG+ GSKG KGEPG+ G               PG +GL GE         PG  
Sbjct: 85  TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144

Query: 680 GSPGEP---------------------------GYMGLPGIQGKKGDKGNQGEKGIQGQK 712
           G PG P                           GY GLPG++G KG KG  GE G QG K
Sbjct: 145 GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204

Query: 713 GENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDP 772
           GE G QG  G+ G QG  GA+G R      G+ G +G KGE G  GL G  GP+G PG P
Sbjct: 205 GEEGDQGELGEVGAQGPPGAQGLR------GITGIVGDKGEKGARGLDGEPGPQGLPGAP 258

Query: 773 GPQ---GPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI 829
           G Q   GPPG  G  G   +E   R +        LP       +   D      G PG 
Sbjct: 259 GDQGQRGPPGEAGPKGDRGAEG-ARGI------PGLPGPKGDTGLPGVDGRDGIPGMPGT 311

Query: 830 PGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQ 889
            G PG  GP G  GL GLPG  G+PG  GV G  G  G  G PG+ G  G      PG+Q
Sbjct: 312 KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK-----PGQQ 366

Query: 890 GPPGPPGPEGPPGI----SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
           GPPG  GP GP G+     + GP G PGLPGK G  G PG+ G PGPPG+
Sbjct: 367 GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 416



 Score =  194 bits (494), Expect = 3e-49
 Identities = 123/309 (39%), Positives = 148/309 (47%), Gaps = 47/309 (15%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
           PG  G+  N        P   + P G  GL G +G+ G  G+PG PG+ G  G PG  G+
Sbjct: 351 PGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGL 410

Query: 484 AGTPGVPGSPGIQGARGLPGYKGEPGRDGDK---------GDRGLPGFPGLHGMPGSKGE 534
            G PG+PG  G +G  G PG KGE G  G++         GD GLPG  G  G PG  G 
Sbjct: 411 PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL 470

Query: 535 MGAKGDKGSPGFYGKK---GAKGEKGNAGFPGLPGPAGEPGR------------------ 573
            G +G +G PG  G +   G +G +G  G  GLPG  G PGR                  
Sbjct: 471 RGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEH 530

Query: 574 ------------HGKDGLMGSPGFKGEAGSPGA---PGQDGTRGEPGIPGFPGNRGLMGQ 618
                        G  GL G PG  G  G PG    PGQ G RG PGI G PG  GL G 
Sbjct: 531 FAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP 590

Query: 619 KGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA 678
           KG++G  G++G  G  G  GL G+ G PG PG P S G  G  G +G PG +G+ G PG 
Sbjct: 591 KGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGP 648

Query: 679 TGSPGEPGY 687
            G PG PG+
Sbjct: 649 PGPPGLPGF 657



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 53/135 (39%), Positives = 60/135 (44%), Gaps = 22/135 (16%)

Query: 455 GPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGD- 513
           G  G PG PG PG PG PG++G PG  GI G PG+ G PG  G RG  G  GE G  G  
Sbjct: 544 GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPP 603

Query: 514 -KGDRGLPGFPGLHGMPG--SKGEMGAKGDK------------------GSPGFYGKKGA 552
            +G  GLPG  GL G PG  S G  G  G++                  G PGF      
Sbjct: 604 GRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 663

Query: 553 KGEKGNAGFPGLPGP 567
             + G   F   P P
Sbjct: 664 TMQAGQRAFNKGPDP 678



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 33/62 (53%), Positives = 36/62 (58%), Gaps = 7/62 (11%)

Query: 884 GYPGEQGPPGPPGPEGPPGIS-------KEGPPGDPGLPGKDGDHGKPGIQGQPGPPGIC 936
           G PGEQGPPGPPGP G PGI         +GPPG PG  G+ G  G PG  G PG  G+ 
Sbjct: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85

Query: 937 DP 938
            P
Sbjct: 86  GP 87


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  431 bits (1109), Expect = e-120
 Identities = 238/521 (45%), Positives = 288/521 (55%), Gaps = 15/521 (2%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
           PG  G    G +D+     P ICPPG P   GP G PG  G  GY G+ G+ GK G +G 
Sbjct: 159 PGHPGVLPEGATDL---QCPSICPPGPP---GPPGMPGFKGPTGYKGEQGEVGKDGEKGD 212

Query: 484 AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
            G PG  G PG  G +G  G +G PG  G  GDRG  GF G  G+PG+ G+ G +G++G 
Sbjct: 213 PGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGP 272

Query: 544 PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
            GF G KG  G  G  G PG+ GP+GEPG  GKDG  G PG  G+ G  G  G  G +G 
Sbjct: 273 EGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGP 332

Query: 604 PGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGI 663
            G+PG PG  G  G+KGE G  G+ G+ G  G PG+ G  G PG+ G  G +GS G  G 
Sbjct: 333 NGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGP 392

Query: 664 QGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ 723
           QG PGA G++G  G  GS G+PG  G  G++G  GD+G  G  G +G +G  G  G+PG 
Sbjct: 393 QGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGD 452

Query: 724 QGIQGHH---GAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGL 780
           +G  G     G KGE G +GE G +G  G  G SGV G+ GP GP G  G PG  G  G 
Sbjct: 453 KGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGK 512

Query: 781 DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG 840
            G PG+E SEQ IR++C  +I  Q+  L  +  +R         GS G PGP GP GP G
Sbjct: 513 PGVPGKEASEQRIRELCGGMISEQIAQL--AAHLRK----PLAPGSIGRPGPAGPPGPPG 566

Query: 841 PRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGP 900
           P G  G PG  G PG  G  G  G  G +G  G  G+KG+ G G  G +G  GP GP+G 
Sbjct: 567 PPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGV 626

Query: 901 PGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLC 941
           PG SK+G  G PG PG  GD G PG  G  G PGICD S C
Sbjct: 627 PGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSAC 667



 Score =  348 bits (894), Expect = 1e-95
 Identities = 215/507 (42%), Positives = 255/507 (50%), Gaps = 51/507 (10%)

Query: 461 GLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLP 520
           GLPG PG PG PG+ G+ G  G AG PG+PG PG +GA G PG  GE G  G  G  GL 
Sbjct: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88

Query: 521 GFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLM 580
           G  G  G  G+ GE G+ G  G PG  G KG  G  G AG  G PG  G  G  G  GL 
Sbjct: 89  GRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147

Query: 581 GSPGFKGEAGSPGAPG---------------QDGTRGEPGIPGFPGNRGLMGQKGEIGPP 625
           G PG  G  G PG PG                 G  G PG+PGF G  G  G++GE+G  
Sbjct: 148 GLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKD 207

Query: 626 GQQGKKGAPGMPGLMGS---------NGSPGQPGTPGSKGS---KGEPGIQGMPGASGLK 673
           G++G  G PG  GL GS          G PG  G PG +G    +G PGI G PG +G +
Sbjct: 208 GEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDR 267

Query: 674 GEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAK 733
           GE G  G  G  G +G PG +G  G  G  GE G+ G+ G+NG  G+ GQ+G  G +GA 
Sbjct: 268 GERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAP 327

Query: 734 GERGEKGEPGVRGAIGSKGESGVDGL---MGPAGPKGQPGDPGPQGPPGLDGKPGREFSE 790
           GE+G  G PG+ G  GSKGE G  G    +G AGP G+PG PG  G PG  G+ G   S 
Sbjct: 328 GEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGS- 386

Query: 791 QFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPP---GPIGPEGPRGLPGL 847
                     +  Q P    +  +R         G PG+PGP    G +G  GP G  G 
Sbjct: 387 -------AGALGPQGPP--GAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGP 437

Query: 848 PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEG 907
            G  G+ G  G+PG  G  G  GL G  GE GS+     GE GP G  GP G  G+  +G
Sbjct: 438 KGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR-----GELGPKGTQGPNGTSGV--QG 490

Query: 908 PPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            PG PG  G  G  G PGI G+PG PG
Sbjct: 491 VPGPPGPLGLQGVPGVPGITGKPGVPG 517



 Score =  281 bits (718), Expect = 3e-75
 Identities = 175/441 (39%), Positives = 206/441 (46%), Gaps = 86/441 (19%)

Query: 535 MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594
           +G  G  G PG  GK G  G  G AG PGLPGP G  G  GK      PG  GEAG PG 
Sbjct: 28  VGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGK------PGKPGEAGLPGL 81

Query: 595 PGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQ--GKKGAPGMPGLMGSNGSPGQPGTP 652
           PG DG  G  G PG    +G  G++G +GPPG    G KG PG PG  G +G PG  G  
Sbjct: 82  PGVDGLTGRDGPPG---PKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLR 138

Query: 653 GSKGSKGEPGIQGMPGASGLKGEPGATGS------------PGEPGYMGLPGIQGKKGDK 700
           G  G  G PG+ G PG  G  G PG                PG PG  G+PG +G  G K
Sbjct: 139 GPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYK 198

Query: 701 GNQGEKGIQGQKGE---NGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVD 757
           G QGE G  G+KG+    G  G+PG  G+QG  G +G  G  G PG RG IG +G  G+ 
Sbjct: 199 GEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIP 258

Query: 758 GLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNC 817
           G  G AG +G+ G  G +GP G  G+PG +                              
Sbjct: 259 GAPGKAGDRGERGPEGFRGPKGDLGRPGPK------------------------------ 288

Query: 818 DHCLSQHGSPGIPGP---PGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                  G+PG+ GP   PG  G +G  G+PGL G+ G  G  G PG  G  GL GLPGR
Sbjct: 289 -------GTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGR 341

Query: 875 NGEKGSQG-------FGYPGEQGPPGPPGPEGPPG-------------ISKEGPPGDPGL 914
            G KG +G        G  G  G PG PG  G PG             +  +GPPG PG+
Sbjct: 342 AGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV 401

Query: 915 PGKDGDHGKPGIQGQPGPPGI 935
            G  G  G  G  G PGP G+
Sbjct: 402 RGFQGQKGSMGDPGLPGPQGL 422



 Score =  275 bits (703), Expect = 1e-73
 Identities = 173/444 (38%), Positives = 207/444 (46%), Gaps = 91/444 (20%)

Query: 557 GNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLM 616
           G  G PG PGP G+PG+ G DG  G PG  G  G  GAPG+ G  GE G+PG PG  GL 
Sbjct: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88

Query: 617 GQKGEIGP---PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLK 673
           G+ G  GP   PG++G  G PG PGL G  G PG PG  G  G  G  G++G PG SGL 
Sbjct: 89  GRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLP 147

Query: 674 GEPGATGSPGEPGYMG------------------------LPGIQGKKGDKGNQGEKGIQ 709
           G PG  G PG PG+ G                        +PG +G  G KG QGE G  
Sbjct: 148 GLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKD 207

Query: 710 GQKGENGRQG---IPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPK 766
           G+KG+ G  G   +PG  G+QG  G +G  G  G PG RG IG +G  G+ G  G AG +
Sbjct: 208 GEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDR 267

Query: 767 GQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGS 826
           G+ G  G +GP G  G+PG +                                     G+
Sbjct: 268 GERGPEGFRGPKGDLGRPGPK-------------------------------------GT 290

Query: 827 PGIPGP---PGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG- 882
           PG+ GP   PG  G +G  G+PGL G+ G  G  G PG  G  GL GLPGR G KG +G 
Sbjct: 291 PGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGE 350

Query: 883 ------FGYPGEQGPPGPPGPEGPPGISKE----------GPPGDPGLPGKDGDHGKPGI 926
                  G  G  G PG PG  G PG   E          GP G PG PG  G  G+   
Sbjct: 351 RGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQ--- 407

Query: 927 QGQPGPPGICDPSLCFSVIARRDP 950
           +G  G PG+  P      +  R P
Sbjct: 408 KGSMGDPGLPGPQGLRGDVGDRGP 431



 Score =  226 bits (576), Expect = 8e-59
 Identities = 145/391 (37%), Positives = 181/391 (46%), Gaps = 84/391 (21%)

Query: 447 PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPG------VPGSPGIQGARG 500
           P G PG+ GP G+PG+PG  G  G PG DG+ G  G  G PG      +PG PG  G++G
Sbjct: 287 PKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKG 346

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG------AKGDKGSPGFYGKKGAKG 554
             G +G  G  G+ G  G PG PG  GMPG +GE G      A G +G PG  G +G +G
Sbjct: 347 EKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQG 406

Query: 555 EKGNAGFPGLPGPAG------------------EPGRHGKDGLMGSPGFKGEAGSPGAPG 596
           +KG+ G PGLPGP G                  + G  G DGL G  G  G +G  G  G
Sbjct: 407 QKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKG 466

Query: 597 QDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQ-------- 648
           + G+RGE G  G  G  G  G +G  GPPG  G +G PG+PG+ G  G PG+        
Sbjct: 467 ESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIR 526

Query: 649 -----------------------------------PGTPGSKGSKGEPGIQGMPGASGLK 673
                                              PG PG  GS G PG +G PG  G  
Sbjct: 527 ELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPT 586

Query: 674 GE---PGATGSPGEPGYMGLPG--IQGKKGDKGNQGEKGI-----QGQKGENGRQGIPGQ 723
           GE   PG  G+ G+ G  G  G  + G +GD+G QG +G+      GQ G  G  G PG 
Sbjct: 587 GELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGD 646

Query: 724 QGIQGHHGAKGERGEKGEPGVRGAI-GSKGE 753
            G+ G  GA+G  G       +GA+ G  GE
Sbjct: 647 PGLPGAIGAQGTPGICDTSACQGAVLGGVGE 677



 Score =  219 bits (559), Expect = 7e-57
 Identities = 139/353 (39%), Positives = 168/353 (47%), Gaps = 70/353 (19%)

Query: 623 GPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
           GPPG  G  G PG  G+ G  G PG PG PG KG+ G+PG            +PG  G P
Sbjct: 32  GPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPG------------KPGEAGLP 79

Query: 683 GEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEP 742
                 GLPG+ G  G  G  G KG  G++G  G  G PG  G +G  G  GE G  G P
Sbjct: 80  ------GLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGG-KGLPGPPGEAGVSGPP 132

Query: 743 GVRGAIGSKGESGVDGLMGPAGPKGQPGDPG---------------PQGPPGLDGKPGRE 787
           G  G  G  G SG+ GL GP GP G PG PG               P GPPG  G PG  
Sbjct: 133 GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPG-- 190

Query: 788 FSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGP---PGPIGPEGPRGL 844
                         +       + G +        + G PG PGP   PG +G +GPRGL
Sbjct: 191 -------------FKGPTGYKGEQGEVGKD----GEKGDPGPPGPAGLPGSVGLQGPRGL 233

Query: 845 PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGI 903
            GLPG  G PG  G  G  G  G+ G PG+ G++G +G  G+ G +G  G PGP+G PG+
Sbjct: 234 RGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGV 293

Query: 904 SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPN 956
           +  GP G+PG+PGKDG +G PG+ GQ G  G               P  KGPN
Sbjct: 294 A--GPSGEPGMPGKDGQNGVPGLDGQKGEAG-----------RNGAPGEKGPN 333



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 46/100 (46%), Positives = 53/100 (53%), Gaps = 17/100 (17%)

Query: 850 RDGVPGLVGVPGRP---------GVRGLKGLPGRNGEKGSQGF-GYPGEQGPPGPPGPEG 899
           R G+PG  G PG P         G  G  GLPG  G KG+ G  G PGE G PG PG +G
Sbjct: 27  RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDG 86

Query: 900 PPGISKEGPPGDPGLPGKDGDHGKPGI-----QGQPGPPG 934
             G  ++GPPG  G PG+ G  G PG      +G PGPPG
Sbjct: 87  LTG--RDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 42/85 (49%), Positives = 47/85 (55%), Gaps = 7/85 (8%)

Query: 857 VGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPG 916
           VG+PG PG  G  G PG++G  G  G   PG  GPPGP G  G PG  K G  G PGLPG
Sbjct: 28  VGLPGPPGPPGPPGKPGQDGIDGEAG--PPGLPGPPGPKGAPGKPG--KPGEAGLPGLPG 83

Query: 917 KDGDHGK---PGIQGQPGPPGICDP 938
            DG  G+   PG +G PG  G   P
Sbjct: 84  VDGLTGRDGPPGPKGAPGERGSLGP 108



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 33/58 (56%), Positives = 36/58 (62%), Gaps = 1/58 (1%)

Query: 879 GSQGFGYPGEQGPPGPPGPEGPPGISKE-GPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
           G+Q  G PG  GPPGPPG  G  GI  E GPPG PG PG  G  GKPG  G+ G PG+
Sbjct: 24  GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGL 81



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 30/68 (44%), Positives = 34/68 (50%), Gaps = 5/68 (7%)

Query: 436 DVGSTPAPCICPPGKPGLQGPKGDPGLP-----GNPGYPGQPGQDGKPGYQGIAGTPGVP 490
           D G+  A    P G  G QGP+G PG       G PG PG PG  G PG  G  GTPG+ 
Sbjct: 603 DKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGIC 662

Query: 491 GSPGIQGA 498
            +   QGA
Sbjct: 663 DTSACQGA 670



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/37 (48%), Positives = 22/37 (59%)

Query: 902 GISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
           G  + G PG PG PG  G  G+ GI G+ GPPG+  P
Sbjct: 24  GAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGP 60


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  427 bits (1097), Expect = e-119
 Identities = 263/601 (43%), Positives = 302/601 (50%), Gaps = 123/601 (20%)

Query: 424  PGFNGECLNGPS-DVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            PGF G  + GP  D G+         G PG+ G  G PGLPG  G PG PG  G  G  G
Sbjct: 831  PGFPGLDMPGPKGDKGAQ--------GLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMG 882

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGE------------PGRDGDKGDRGLPGFPG------ 524
            + GTPG PGSPG  GA GLPG KG+            PG  GDKGD GLPG PG      
Sbjct: 883  VMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVD 942

Query: 525  LHGMPGSKGEMGAKG------DKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDG 578
            +  M G KG+ G KG      +KGS G  G  G  G+ G AG PG PGP G+PG  G  G
Sbjct: 943  MGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPG 1002

Query: 579  LMGSPGFKGEAGSPGAPGQDGTRGEPGIPG------FPGNRGLMGQKGEIGPPGQQGKKG 632
              G PG KG  G  G PG  G +G PGIPG       PG++G  G+KG+ GPPG     G
Sbjct: 1003 APGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI----G 1058

Query: 633  APGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMG--- 689
             PG+ G  G  G  G PG+PG KG KG  GI GMPG+ GLKG PG+ G PG PG  G   
Sbjct: 1059 IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKG 1118

Query: 690  ---------LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ-----------QGIQGH 729
                     +PG++G+ G  G  G  G  GQKGE G  GIPG            +G  G 
Sbjct: 1119 DKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGF 1178

Query: 730  HGAKGERGEKGE---PGVRGAIGSKGESGVDGLMGPAGPKGQPG--------------DP 772
             GAKG++G KGE   PG+ G+ G  G  G  G MGP GP+GQPG              D 
Sbjct: 1179 PGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDR 1238

Query: 773  GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGP 832
            GPQG PGL G PG                       +    +   D      G+PG PG 
Sbjct: 1239 GPQGQPGLPGLPGP----------------------MGPPGLPGIDGVKGDKGNPGWPGA 1276

Query: 833  PGPIGPEGPRGLPGLPGRDGVPGL------VGVPGRPGVRGLKGLPGRNGEKGSQGF-GY 885
            PG  GP+G  G  G+PG  G PG+      +G PG PG +G KGLPG  G KG QG  G 
Sbjct: 1277 PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGV 1336

Query: 886  PGEQGPPGPPGPEGPPGISK--------EGPPGDPGL---PGKDGDHGKPGIQGQPGPPG 934
            PG +G PGPPGP GP  I K        EGPPG  GL   PG  G  G  G+ G PGPPG
Sbjct: 1337 PGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPG 1396

Query: 935  I 935
            I
Sbjct: 1397 I 1397



 Score =  402 bits (1034), Expect = e-112
 Identities = 244/578 (42%), Positives = 287/578 (49%), Gaps = 107/578 (18%)

Query: 423  IPGFNGECLNGPSDVGSTPAP--CICPPGKPGLQGPKGDPGLPGNPGYPGQPG--QDGKP 478
            IPG  GE   G   V   P     I PPG  G++G  G PGLPG+ G PG PG    G  
Sbjct: 750  IPGTPGE--KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGAR 807

Query: 479  GYQGIAGTPGVPGSPGIQGARGLPGYKG--EPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536
            G  G  G PG+ G PGI+G +G PG+ G   PG  GDKG +GLPG  G  G+PG  G+ G
Sbjct: 808  GPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQG 867

Query: 537  AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPG 596
            A G    PGF G KG  G  G  G PG PGP G PG  G+ G  G PG  G  G PG  G
Sbjct: 868  APG---IPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKG 924

Query: 597  QDGTRGEPGIPG---------FPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPG 647
              G  G PG PG           G +G  G+KG+IGP G++G +G PG PG+ G +G  G
Sbjct: 925  DKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAG 984

Query: 648  QPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707
            QPG PG KG  G  G  G PG  G KG  G  G PG PG  G+PGI G +G  G  G+KG
Sbjct: 985  QPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKG 1044

Query: 708  IQGQKGENGRQGI--------PGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGL 759
             +G+KG+ G  GI         G QGI G  G+ GE+GEKG  G+ G  GS G  G  G 
Sbjct: 1045 AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS 1104

Query: 760  MGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDH 819
            +G  G  G PG+ G +G PGLDG PG +                                
Sbjct: 1105 VGYPGSPGLPGEKGDKGLPGLDGIPGVK-------------------------------- 1132

Query: 820  CLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGV--RGLKGLPGRNGE 877
                 G  G+PG PGP GP G +G PG    DG+PG  G  G PG+  RG  G PG  G+
Sbjct: 1133 -----GEAGLPGTPGPTGPAGQKGEPG---SDGIPGSAGEKGEPGLPGRGFPGFPGAKGD 1184

Query: 878  KGSQG-FGYPG------------EQGPPGPPGPEGPPGI------SKEGPPGD------- 911
            KGS+G  G+PG            EQG  GPPGP+G PG+      + EGP GD       
Sbjct: 1185 KGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQP 1244

Query: 912  -----------PGLPGKDGDHGKPGIQGQPGPPGICDP 938
                       PGLPG DG  G  G  G PG PG+  P
Sbjct: 1245 GLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGP 1282



 Score =  397 bits (1019), Expect = e-110
 Identities = 229/494 (46%), Positives = 270/494 (54%), Gaps = 52/494 (10%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEP 508
            G+PG  GPKGDPG+ G PG PG PG  G  G  G+ GTPG  G PGI G +G PG  G+ 
Sbjct: 984  GQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDK 1043

Query: 509  GRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPA 568
            G  G+KG  G PG     G+PG +GE   KGD+G  GF G  G KGEKG+ G PG+PG  
Sbjct: 1044 GAKGEKGQAGPPGI----GIPGLRGE---KGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP 1096

Query: 569  GEPGRHGKDGLMGSPGFKGEAGSPGAPGQDG---TRGEPGIPGFPGNRGLMGQKGEIGP- 624
            G  G  G  G  GSPG  GE G  G PG DG    +GE G+PG PG  G  GQKGE G  
Sbjct: 1097 GLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSD 1156

Query: 625  --PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE---PGIQGMPGASGLKGEPGAT 679
              PG  G+KG PG+PG     G PG PG  G KGSKGE   PG+ G PG  G KGE G  
Sbjct: 1157 GIPGSAGEKGEPGLPG----RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFM 1212

Query: 680  GSPGEPGYMGLPG-----IQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG--- 731
            G PG  G  GLPG      +G KGD+G QG+ G+ G  G  G  G+PG  G++G  G   
Sbjct: 1213 GPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPG 1272

Query: 732  ---AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREF 788
               A G  G KG+PG +G  G  G  G+ G  G  GP G PG  GP+G PGL G  G + 
Sbjct: 1273 WPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQG 1332

Query: 789  SEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLP 848
             +          +     +    G     D      G PG+PGP GP G +G +GLPG  
Sbjct: 1333 DQG---------VPGAKGLPGPPGPPGPYDII---KGEPGLPGPEGPPGLKGLQGLPGPK 1380

Query: 849  GRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGP 908
            G+ GV GLVG+PG PG+ G  G PG+ GE G    G  G +G PGPPGP+G PG    GP
Sbjct: 1381 GQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPA--GPTGPRGFPGPPGPDGLPG--SMGP 1436

Query: 909  PGDPGLPGKDGDHG 922
            PG P +     DHG
Sbjct: 1437 PGTPSV-----DHG 1445



 Score =  389 bits (999), Expect = e-108
 Identities = 242/577 (41%), Positives = 291/577 (50%), Gaps = 92/577 (15%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICP--PGKPGLQGPKGDPGLPGNPGYPGQPGQ------ 474
            +PG  GE    P  +   P P      PG PG  GP+GD G PG PG PG PG+      
Sbjct: 631  LPGPKGE----PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQ 686

Query: 475  --------------DGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLP 520
                          DG PG  G  GTPG PG  G+ G  G+ G KGEPG  G  G +GLP
Sbjct: 687  PGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV-GLPGLKGLP 745

Query: 521  GFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPG-------- 572
            G PG+ G PG KG +G  G  G  G  G  G +G +G  G PGLPG  G PG        
Sbjct: 746  GLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPG 805

Query: 573  ------RHGKDGLMGSPGFKGEAGSPGAPGQD--GTRGEPGIPGFPGNRGLMGQKGEIGP 624
                    G  GL G PG KGE G PG PG D  G +G+ G  G PG   + GQ G  G 
Sbjct: 806  ARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG---ITGQSGLPGL 862

Query: 625  PGQQGKKGAPGMPGL---MGSNGSPGQPGTPGSKGSKGEPGIQ---GMPGASGLKGEPGA 678
            PGQQG  G PG PG    MG  G+PGQPG+PG  G+ G PG +   G PG+SG +G+PG 
Sbjct: 863  PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGL 922

Query: 679  TGSPGEPGYMGLPG---------IQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGH 729
             G  G+ G  G PG         ++G+KGD+G +G+ G  G+KG  G  G PG  G  G 
Sbjct: 923  KGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQ 982

Query: 730  HGAKGERGEKGEPGVRGAIGS------KGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGK 783
             G  G+ G KG+PG+ G  G+      KG  G  GL G  G KG PG PGPQG PGL G 
Sbjct: 983  AGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGD 1042

Query: 784  PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRG 843
             G +  +           +A  P +   G          + G  GI G PG  G +G +G
Sbjct: 1043 KGAKGEKG----------QAGPPGIGIPG-------LRGEKGDQGIAGFPGSPGEKGEKG 1085

Query: 844  LPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEG 899
              G+PG  G PGL G PG  G  G  GLPG  G+KG  G     G  GE G PG PGP G
Sbjct: 1086 SIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTG 1145

Query: 900  PPGISKEGPPGDPGLPGKDGDHGKPGIQGQ--PGPPG 934
            P G  ++G PG  G+PG  G+ G+PG+ G+  PG PG
Sbjct: 1146 PAG--QKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPG 1180



 Score =  384 bits (987), Expect = e-106
 Identities = 246/554 (44%), Positives = 285/554 (51%), Gaps = 74/554 (13%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PGF G+    P   G   +P     G PGL GPKG PG  G  G  G PG  G PG +G 
Sbjct: 546  PGFPGQ----PGMTGRAGSPG--RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGD 599

Query: 484  AGTPGVPGSP-----GIQGARGLPGYKGEPGRDGDKGDRG----LPGFPGLHGMPGSKGE 534
             G PG PG       G +G  G PG  G PG  G KG+ G    LPG PG  G+PGS G 
Sbjct: 600  TGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGF 659

Query: 535  MGAKGDKGSPGFYGKKGAKGEKG-----NAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEA 589
             G +GD+G PG  G+ G  GEKG       GFPG PGP G  G  G  G  G+PG  G  
Sbjct: 660  PGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFN 719

Query: 590  GSPGAPGQDGTRGEPGI--------PGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG 641
            G PG PG  G +GEPG+        PG PG  G  G+KG IG PG  G+ GA G PGL G
Sbjct: 720  GLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQG 779

Query: 642  SNGSPGQPGTPGSKGSKGEPGIQGMPGASGL---KGEPGATGSPG---EPGYMGLPGIQ- 694
              G PG PG PGS GS G PGI G PGA G    +G PG +G PG   E G+ G PG+  
Sbjct: 780  IRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDM 838

Query: 695  -GKKGDKGNQGEKGIQGQKG------ENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGA 747
             G KGDKG QG  GI GQ G      + G  GIPG  G +G  G  G  G+ G PG  GA
Sbjct: 839  PGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGA 898

Query: 748  IGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPV 807
             G  GE G  G  G +GP+G PG  G +G  GL GKPG       + +V    ++ Q   
Sbjct: 899  PGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGS------MDKVDMGSMKGQKGD 952

Query: 808  LLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRG 867
              + G+I      + + GS G PG PG  G +G  G PG PG  G PG+ G PG PG   
Sbjct: 953  QGEKGQIGP----IGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPG--- 1005

Query: 868  LKGLPGRNGEKGSQGF-GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGI 926
               LPG  G  G  G  G PGE+G PG PGP+G PG+     PGD G  G+         
Sbjct: 1006 ---LPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGL-----PGDKGAKGE--------- 1048

Query: 927  QGQPGPPGICDPSL 940
            +GQ GPPGI  P L
Sbjct: 1049 KGQAGPPGIGIPGL 1062



 Score =  384 bits (985), Expect = e-106
 Identities = 253/614 (41%), Positives = 297/614 (48%), Gaps = 116/614 (18%)

Query: 425 GFNGECLNGPSDVGSTPAP----------------CICPPGKPGLQGPKGDPGLPGNPGY 468
           GF G  L GPS     P P                  C PG PG QGP G PG PG  G 
Sbjct: 397 GFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGE 456

Query: 469 PGQPGQDGK-------PGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPG 521
            G+ GQ G+        GY+G  G  G PG  G  G  G  G +G PGRDG  G  G  G
Sbjct: 457 IGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQG 516

Query: 522 FPGLHGMPGSKGEMG-------AKGDKGSPGFYGKKGAKGEKGNA---GFPGLPGPAGEP 571
            PGL G PG+KGE G        KGDKG PGF G+ G  G  G+    G PGLPGP G P
Sbjct: 517 TPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSP 576

Query: 572 ------GRHGKDGLMGSPGFKGEAGSPGAPGQD-----GTRGEPGIPGFPGNRGLMGQKG 620
                 G  G  G +G PG +G+ G PG PG       G +G+ G PG PG+ GL G KG
Sbjct: 577 GSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKG 636

Query: 621 E-------IGPPGQQGKKGAPGMPGLMGSN---GSPGQPGTPGSKGSKGEPGI-----QG 665
           E        GPPG +G  G+PG PG  G     G+PG+PG PG KG+ G+PGI      G
Sbjct: 637 EPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPG 696

Query: 666 MPGASGLKGEPGATGSPGEPGYMGL---PGIQGKKGD--------KGNQGEKGIQGQKGE 714
             G  GL G+ G  G+PG PG+ GL   PG+QG+KG+        KG  G  GI G  GE
Sbjct: 697 PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756

Query: 715 NGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGP 774
            G  G+PG  G  G  G  G +G +GEPG  G  GS G  GV G+    GP G  G PG 
Sbjct: 757 KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI----GPPGARGPPGG 812

Query: 775 QGPPGLDGKPGREFSEQFIRQVCTDVIRAQ-------LP-VLLQSGRIRNCDHCLSQHGS 826
           QGPPGL G PG +  + F      D+   +       LP +  QSG          Q G+
Sbjct: 813 QGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSG----LPGLPGQQGA 868

Query: 827 PGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF--- 883
           PGIPG P   G +G  G+ G PG+ G PG VG PG PG +G  G PG +G +G  G    
Sbjct: 869 PGIPGFP---GSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGD 925

Query: 884 ----------------------GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDH 921
                                 G  G+QG  G  GP G  G    G PG PG+PGKDG  
Sbjct: 926 KGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKG--SRGDPGTPGVPGKDGQA 983

Query: 922 GKPGIQGQPGPPGI 935
           G+PG  G  G PGI
Sbjct: 984 GQPGQPGPKGDPGI 997



 Score =  359 bits (922), Expect = 6e-99
 Identities = 243/616 (39%), Positives = 285/616 (46%), Gaps = 141/616 (22%)

Query: 448 PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
           PG  G +GP+G PG  G+ G PG PG  G  G  G +G PG PG PGI G  G PG  G 
Sbjct: 63  PGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGI 122

Query: 508 PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPG-FYGKKGAKGEKGNAGFPGLPG 566
           PG +G KG+RG  G PGL G  G+ G  G  G KG PG   G       KG  GFPG+PG
Sbjct: 123 PGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPG 182

Query: 567 PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPG 626
             G PG  G  G +G PGF G  G PG PG  G +G+ G+  F G +G  G +G  GPPG
Sbjct: 183 TPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGL-SFQGPKGDKGDQGVSGPPG 241

Query: 627 QQGK-----KGAPGMPGLMGSNGSPGQPGTPG--SKGSKGEPGIQGMPGASGLKGEPGAT 679
             G+     KG     G  G  G PG  G PG   KG  G+PG +G PG  G KGE G+ 
Sbjct: 242 VPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSP 301

Query: 680 GSPGEPGYMGLPGIQGKKGDKGNQGEKGIQG---------QKGENGRQGIPGQQG----- 725
           G PGEPGY GL G QG +G+KG  G  G  G         +KGE G  G PG +G     
Sbjct: 302 GFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPK 361

Query: 726 ---------------IQGHHGAKGERGEKGEPGVRGAIGSK--GESGVDGLMGPAGPKG- 767
                          + G  GA G  GE+GE G RG  G+   G SG DGL GP G  G 
Sbjct: 362 GFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGP 421

Query: 768 -------------QPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
                        QPG PG QGPPG+ G+PG      FI ++     + +  ++      
Sbjct: 422 PGQPGYTNGIVECQPGPPGDQGPPGIPGQPG------FIGEIGEKGQKGESCLICDIDGY 475

Query: 815 RNCDHCLSQHGSPGIPGPPGPIG------PEGPRGLPG------LPGRDGVPGLVG---- 858
           R         G PG  GPPG IG       +G RGLPG      +PG  G PGL+G    
Sbjct: 476 R---------GPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGA 526

Query: 859 ---------------------VPGRPGVRGLKGLPGRNGE------KGSQG-FGYPGEQG 890
                                 PG+PG+ G  G PGR+G       KGS G  G  GE+G
Sbjct: 527 KGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERG 586

Query: 891 PP---------GPPGPEGPPGISKEGP------------PGDPGLPGKDGDHGK------ 923
           PP         G  GP GPPG    GP            PG PGLPG  G+ GK      
Sbjct: 587 PPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPG 646

Query: 924 -PGIQGQPGPPGICDP 938
            PG +G PG PG   P
Sbjct: 647 PPGAEGLPGSPGFPGP 662



 Score =  359 bits (921), Expect = 8e-99
 Identities = 242/598 (40%), Positives = 282/598 (47%), Gaps = 119/598 (19%)

Query: 438 GSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK---PGYQGIAGTPGVPGSPG 494
           GS    C C  G  G +G +G PGL G  G+PG  G +G    PG +G  G PG+PG+ G
Sbjct: 33  GSGCGKCDCH-GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKG 91

Query: 495 IQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGK----- 549
            +G  G  GY G PG  G  G  G PG PG+ G  G+KGE G  G  G PGF G      
Sbjct: 92  TRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPG 151

Query: 550 ----KGAKGE----------KGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP 595
               KG  GE          KG  GFPG+PG  G PG  G  G +G PGF G  G PG P
Sbjct: 152 LPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPP 211

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQG-----KKGAPGMPGLMGSNGSPGQPG 650
           G  G +G+ G+  F G +G  G +G  GPPG  G     +KG     G  G  G PG  G
Sbjct: 212 GPPGEKGQMGL-SFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQG 270

Query: 651 TP--GSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
            P  G KG  G+PG +G PG  G KGE G+ G PGEPGY GL G QG +G+KG  G  G 
Sbjct: 271 MPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGP 330

Query: 709 Q---------GQKGENGRQGIPGQQG--------------------IQGHHGAKGERGEK 739
                     G+KGE G  G PG +G                    + G  GA G  GE+
Sbjct: 331 PGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGER 390

Query: 740 GEPGVRGAIGSK--GESGVDGLMGPAGPKG--------------QPGDPGPQGPPGLDGK 783
           GE G RG  G+   G SG DGL GP G  G              QPG PG QGPPG+ G+
Sbjct: 391 GEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQ 450

Query: 784 PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI------G 837
           PG      FI ++     + +  ++        CD      G PG  GPPG I      G
Sbjct: 451 PG------FIGEIGEKGQKGESCLI--------CD-IDGYRGPPGPQGPPGEIGFPGQPG 495

Query: 838 PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR-------NGEKGSQGF------- 883
            +G RGLPG  G  GVPG  G PG  G  G KG PG         G+KG  GF       
Sbjct: 496 AKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMT 555

Query: 884 ---GYPGEQGPPGPPGPEGPPGI----SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
              G PG  G PG PGP+G PG      + GPPG  G PG  GD G PG  G  GP G
Sbjct: 556 GRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAG 612



 Score =  355 bits (912), Expect = 9e-98
 Identities = 231/562 (41%), Positives = 270/562 (48%), Gaps = 90/562 (16%)

Query: 449 GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYK--G 506
           G PG  GP+G+PG  G PG PGQPG  G P   G AG PG PG  G +G RG PG    G
Sbjct: 347 GYPGTPGPRGEPGPKGFPGLPGQPGPPGLP-VPGQAGAPGFPGERGEKGDRGFPGTSLPG 405

Query: 507 EPGRDGDKGDRGLPGFPGLHG--------MPGSKGEMGAKGDKGSPGFYGKKGAKGEKGN 558
             GRDG  G  G PG PG  G         PG  G+ G  G  G PGF G+ G KG+KG 
Sbjct: 406 PSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGE 465

Query: 559 A-------GFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611
           +       G+ G PGP G PG       +G PG  G  G  G PG+DG  G PG  G PG
Sbjct: 466 SCLICDIDGYRGPPGPQGPPGE------IGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPG 519

Query: 612 NRGLMGQKGEIGP-------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQ 664
             G  G KGE G         G +G  G PG PG+ G  GSPG+ G PG  G KG PG  
Sbjct: 520 LIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSV 579

Query: 665 GM------PGASGLKGEPGATGSPGEPGY--MGLPGIQGKKGDKGNQGEKGIQGQKGENG 716
           G+      PG  G  G  G TG PG PGY   G  G +G+ G  G  G  G+ G KGE G
Sbjct: 580 GLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPG 639

Query: 717 R----------QGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPK 766
           +          +G+PG  G  G  G +G  G  G PG+ G  G+ G+ G+ G  GP GPK
Sbjct: 640 KIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPGPK 698

Query: 767 GQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQ-------LPVLLQSGRIRNCDH 819
           G  G PG  GPPG  G+PG      F        ++ Q       LP L     +     
Sbjct: 699 GVDGLPGDMGPPGTPGRPG------FNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPG 752

Query: 820 CLSQHGSPGIPGPP---GPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGV----------- 865
              + GS G+PG P   G IGP G +G+ G PG  G+PG VG PG PG+           
Sbjct: 753 TPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGG 812

Query: 866 ---RGLKGLPGRNGEKGSQGF---------GYPGEQGPPGPPGPEGPPGI-SKEGPPGDP 912
               GL G PG  GEKG  GF         G  G QG PG  G  G PG+  ++G PG P
Sbjct: 813 QGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIP 872

Query: 913 GLPGKDGDHGKPGIQGQPGPPG 934
           G PG  G+ G  G  GQPG PG
Sbjct: 873 GFPGSKGEMGVMGTPGQPGSPG 894



 Score =  306 bits (783), Expect = 8e-83
 Identities = 175/388 (45%), Positives = 207/388 (53%), Gaps = 49/388 (12%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQ------PGQDGK 477
            PG  GE      + GS   P +  PG PGL+G  G  G PG+PG PG+      PG DG 
Sbjct: 1075 PGSPGE----KGEKGSIGIPGM--PGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGI 1128

Query: 478  PGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGA 537
            PG +G AG PG PG  G  G +G PG  G PG  G+KG+ GLPG  G  G PG+KG+ G+
Sbjct: 1129 PGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG-RGFPGFPGAKGDKGS 1187

Query: 538  KGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGR--------------HGKDGLMGSP 583
            KG+ G PG  G  G  G KG  GF G PGP G+PG                G  G  G P
Sbjct: 1188 KGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLP 1247

Query: 584  GFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643
            G  G  G PG PG DG +G+ G PG+PG  G+ G KG+   PG QG  G  G PG+ GS 
Sbjct: 1248 GLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGD---PGFQGMPGIGGSPGITGSK 1304

Query: 644  GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPG----------YMGLPGI 693
            G  G PG PG +G KG PG+QG+ G  G +G PGA G PG PG            GLPG 
Sbjct: 1305 GDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGP 1364

Query: 694  QGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGE 753
            +G  G KG QG  G +GQ+G  G  GIPG  GI G  GA G++GE         +G  G 
Sbjct: 1365 EGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGE---------MGPAGP 1415

Query: 754  SGVDGLMGPAGPKGQPGDPGPQGPPGLD 781
            +G  G  GP GP G PG  GP G P +D
Sbjct: 1416 TGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443



 Score =  236 bits (603), Expect = 6e-62
 Identities = 142/316 (44%), Positives = 163/316 (51%), Gaps = 31/316 (9%)

Query: 423  IPGFNGECLNGPSDVGST-PAPCICPPGK---PGLQGPKGDPGLPGN--PGYPG---QPG 473
            IPG  GE    P   G T PA     PG    PG  G KG+PGLPG   PG+PG     G
Sbjct: 1128 IPGVKGEA-GLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKG 1186

Query: 474  QDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPG--------RDGDKGDRG------L 519
              G+ G+ G+AG+PG+PGS G QG  G PG +G+PG         +G KGDRG      L
Sbjct: 1187 SKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGL 1246

Query: 520  PGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGL 579
            PG PG  G PG  G  G KGDKG+PG+ G  G  G KG+ GF G+PG  G PG  G  G 
Sbjct: 1247 PGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGD 1306

Query: 580  MGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGP-------PGQQGKKG 632
            MG PG  G  G  G PG  G +G+ G  G PG +GL G  G  GP       PG  G +G
Sbjct: 1307 MGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEG 1366

Query: 633  APGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPG 692
             PG+ GL G  G  GQ G  G  G  G PGI G  GA G KGE G  G  G  G+ G PG
Sbjct: 1367 PPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPG 1426

Query: 693  IQGKKGDKGNQGEKGI 708
              G  G  G  G   +
Sbjct: 1427 PDGLPGSMGPPGTPSV 1442



 Score =  178 bits (452), Expect = 2e-44
 Identities = 120/324 (37%), Positives = 144/324 (44%), Gaps = 92/324 (28%)

Query: 650 GTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQ 709
           G  G KG +G PG+QG+ G  G++G  G  G PG+ G  G PG+ G K   G +G  G  
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTK---GTRGPPGAS 99

Query: 710 GQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQP 769
           G  G  G  GIPGQ G              G PG+ G  G+KGE G    +GP G  G  
Sbjct: 100 GYPGNPGLPGIPGQDG------------PPGPPGIPGCNGTKGERGP---LGPPGLPGFA 144

Query: 770 GDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI 829
           G+PGP G PG+ G PG               I   +P +L  G          + G PGI
Sbjct: 145 GNPGPPGLPGMKGDPGE--------------ILGHVPGMLLKG----------ERGFPGI 180

Query: 830 PGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG------- 882
           PG PGP       GLPGL G  G PG  G PG PG       PG  GEKG  G       
Sbjct: 181 PGTPGP------PGLPGLQGPVGPPGFTGPPGPPGP------PGPPGEKGQMGLSFQGPK 228

Query: 883 -------------------------FGYPGEQGPPGPPGPEGPPGISKEGPPGDP---GL 914
                                    F   GE+G  G PG +G PG+ ++G PG P   G 
Sbjct: 229 GDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGK 288

Query: 915 PGKDGDHGK---PGIQGQPGPPGI 935
           PGKDGD G+   PG  G+PG PG+
Sbjct: 289 PGKDGDKGEKGSPGFPGEPGYPGL 312



 Score =  120 bits (302), Expect = 5e-27
 Identities = 85/222 (38%), Positives = 98/222 (44%), Gaps = 68/222 (30%)

Query: 423  IPGFNGECLNGPSD---------VGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPG 473
            +PG  G    GP           +   P P + PPG PG+ G KGD G PG PG PG PG
Sbjct: 1223 LPGSPGHATEGPKGDRGPQGQPGLPGLPGP-MGPPGLPGIDGVKGDKGNPGWPGAPGVPG 1281

Query: 474  QDGKPGYQG---IAGTPGV---------PGSPGIQGARGLPGYKGEPGRDGDKG---DRG 518
              G PG+QG   I G+PG+         PG PG QG +GLPG +G  G  GD+G    +G
Sbjct: 1282 PKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKG 1341

Query: 519  LPGFPG-------------------------LHGMPGSKGEMGAKG------DKGSPGFY 547
            LPG PG                         L G+PG KG+ G  G        G PGF 
Sbjct: 1342 LPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFD 1401

Query: 548  GKKGAKGEKGNAG------FPGLPGP------AGEPGRHGKD 577
            G  G KGE G AG      FPG PGP       G PG    D
Sbjct: 1402 GAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  422 bits (1086), Expect = e-118
 Identities = 242/539 (44%), Positives = 290/539 (53%), Gaps = 58/539 (10%)

Query: 446  CPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGI---QGARGLP 502
            CPPG PGL G    PG  G+ G PG+PG++G  G +G AG PG+PG PGI   QG++G  
Sbjct: 564  CPPGPPGLPGL---PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 620

Query: 503  GYKGEPGRDGDKGDRGLPGF---------------------PGLHGMPGSKGEMGAKGDK 541
            G  GE G+ GD+G  G+PGF                     PG+ G PG +G  G +G  
Sbjct: 621  GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 680

Query: 542  GSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTR 601
            G PG  G++G +G  G  G PG PG AGEPG  G +G  G PGFKG  G  GAP   G R
Sbjct: 681  GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAP---GPR 737

Query: 602  GEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP---GTPGSKGSK 658
            GE G  G PG  GL G+ G+ GP G QG +G  G PG  GS GSPG+P   GTPG KGSK
Sbjct: 738  GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 797

Query: 659  GEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQ 718
            GE G  G+PG  G +G PG  G  G PG  G+PG  G+ G KG +G+ GI+G KG  G +
Sbjct: 798  GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 857

Query: 719  GIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPP 778
            G PG  GI GH G  G  G +G PG  G +            GP GP GQPG PG +G  
Sbjct: 858  GQPGDPGIPGHKGHTGLMGPQGLPGENGPV------------GPPGPPGQPGFPGLRGE- 904

Query: 779  GLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP 838
                 P  E   + I++     +  +L  LL         +  S  G PG PGPPG  G 
Sbjct: 905  ----SPSMETLRRLIQEELGKQLETRLAYLLAQ---MPPAYMKSSQGRPGPPGPPGKDGL 957

Query: 839  EGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPE 898
             G  G  G PGR   PG  G+ G  G  G KG  G  G+ G+ G G  GE GPPG PG  
Sbjct: 958  PGRAGPMGEPGR---PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQP 1014

Query: 899  GPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLC--FSVIARRDPFRKGP 955
            G PG +K+G PG PG  G+ G  G PG+ G PGPPG CDPS C  F+ +A R    KGP
Sbjct: 1015 GEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1073



 Score =  384 bits (986), Expect = e-106
 Identities = 247/637 (38%), Positives = 298/637 (46%), Gaps = 139/637 (21%)

Query: 433 GPSDV-GSTPAPCI-CPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVP 490
           GP+D      A CI      PGL+   G+PG  G  G PG+PG  G+ G QG+AG PG  
Sbjct: 223 GPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEK 282

Query: 491 GSPGIQGARGLPGYKGEPGRDGDKGDRGLPGF---------------PGLHG-------- 527
           G  G+ GA G PG +GE G  G+KG+ GLPG                PGL G        
Sbjct: 283 GEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH 342

Query: 528 --MPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGF 585
             MPG +G  G KGD G PG  G +G  GE G  G  G PG  G+ G HG  G  G+PG 
Sbjct: 343 PRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA 402

Query: 586 KGEAGSP---------------GAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPP----- 625
            G  G+P               G PG+DG RGE G  G  G+ G +G +G+ G P     
Sbjct: 403 PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP 462

Query: 626 ------GQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGI--------------QG 665
                 G+ G +G+PG+PG +G+ G  G PG PGS GS+G+PGI              +G
Sbjct: 463 PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 522

Query: 666 MPGASGLKGEPGATG---------------------------SPGEPGYMGLPGIQGKKG 698
            PG+ GL G PG  G                            PG PG  GLPG +G KG
Sbjct: 523 SPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG 582

Query: 699 DKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGE------------PGVRG 746
             G  G +G +G+KGE G  G+PG  GI G  G++GERG  GE            PG  G
Sbjct: 583 VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 642

Query: 747 AIGSKGESGVDGLMGPAGP------KGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCT-- 798
             G+ G  G DG+ G AGP       G+ G PGPQGP GL G PG E  E    +     
Sbjct: 643 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPG 702

Query: 799 DVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGP---------------------PGPIG 837
           +  +A  P L      R         G  G PGP                      GP G
Sbjct: 703 EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 762

Query: 838 PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGP 897
           P+GP+G  G PG++G PG  G PG  G  G KG  G NG  G  GF   G +GPPG PG 
Sbjct: 763 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF--LGPRGPPGEPGE 820

Query: 898 EGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           +G PG  KEG PG PG PG  G+ G PGI+G  GPPG
Sbjct: 821 KGVPG--KEGVPGKPGEPGFKGERGDPGIKGDKGPPG 855



 Score =  281 bits (718), Expect = 3e-75
 Identities = 174/416 (41%), Positives = 209/416 (50%), Gaps = 54/416 (12%)

Query: 562 PGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGE 621
           PGL    GEPG  G+DGL G PG +GE G  G  G+ G +GE G+PG PG  G+ G+KG+
Sbjct: 243 PGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 302

Query: 622 IGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGI----QGMPGASGLKGEPG 677
                 QG+KG  G+PGL G  G  G+ G  G  G  G   +      MPG  G KGE G
Sbjct: 303 ------QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG 356

Query: 678 ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             G PGEPG  G PG  G +G  G  G KG +G  G  G  G PG  G  G  G  G  G
Sbjct: 357 DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG 416

Query: 738 EKGEPGVRGA------IGSKGESGVDGLMGPAGPKGQPGDPGPQGPP--GLDGKPGREFS 789
             G PG+RG        G KG +G +G  GP GP+G PG PG  GPP  G DG+PG   S
Sbjct: 417 SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS 476

Query: 790 EQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLP- 848
                 + T   R   P +  S   R  D  +   G PG  GPPG  G  G RGLPG P 
Sbjct: 477 PGLPGPLGTKGDRG-APGIPGSPGSRG-DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG 534

Query: 849 -----GRDGV---------------------PGLVGVPGRPGVRGLKGLPGRNGEKGSQG 882
                GRDG+                     PG  G+PG PG +G KG+PG+ G +G++ 
Sbjct: 535 PQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE- 593

Query: 883 FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
               G++G  GPPG  GPPGI+  GP G  G  G DG+ G+ G QG PG PG   P
Sbjct: 594 ----GKKGEAGPPGLPGPPGIA--GPQGSQGERGADGEVGQKGDQGHPGVPGFMGP 643



 Score =  241 bits (616), Expect = 2e-63
 Identities = 166/446 (37%), Positives = 208/446 (46%), Gaps = 83/446 (18%)

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAG 560
           L G + +P  + D+G +G  G      +P S           +P     KG  G + +A 
Sbjct: 170 LLGPRTDPWENVDQGAQGACGRGNTSVLPSSV----------APQCSMPKGT-GHEFSAA 218

Query: 561 FPGLPGPAGEPGRHGKDGLMGS---PGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMG 617
             G  GPA +        ++ +   PG K   G PG       RGE G+PG PG RG +G
Sbjct: 219 L-GTQGPADQRADARASCILAAKTAPGLKQLNGEPGE------RGEDGLPGKPGLRGEIG 271

Query: 618 QKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
           ++G  G PG++G+ G PG PG       PG  G  G +G KGE G+ G+ G  G KGE G
Sbjct: 272 EQGLAGRPGEKGEAGLPGAPGF------PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAG 325

Query: 678 ATGSPGEPGYMGL----PGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAK 733
             G PG PG   L    P + G++G KG +G+ G+ G+ G  GR G  G QG  G  GAK
Sbjct: 326 PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK 385

Query: 734 GERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFI 793
           G+ G  G PG   A G+ G  G  G  GP+GP G  G PG +G PG DG+ G +      
Sbjct: 386 GQEGAHGAPG---AAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK------ 436

Query: 794 RQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGV 853
                                          G+ G  G PGP+GP G  G PGLPG  G 
Sbjct: 437 -------------------------------GAAGEEGSPGPVGPRGDPGAPGLPGPPGK 465

Query: 854 PGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPG 913
               G  G PG+RG  GLPG  G KG +G       G PG PG  G PGI   GPPG  G
Sbjct: 466 ----GKDGEPGLRGSPGLPGPLGTKGDRG-----APGIPGSPGSRGDPGIGVAGPPGPSG 516

Query: 914 LPGKDGDHGKPGIQGQPGPPGICDPS 939
            PG   D G PG +G PG PG   P+
Sbjct: 517 PPG---DKGSPGSRGLPGFPGPQGPA 539



 Score =  219 bits (559), Expect = 7e-57
 Identities = 161/471 (34%), Positives = 193/471 (40%), Gaps = 123/471 (26%)

Query: 564 LPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQD-----GTRGEPGIPGFPGNRGLMGQ 618
           L GP  +P  +   G  G+ G    +  P +         GT  E       G +G   Q
Sbjct: 170 LLGPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHE--FSAALGTQGPADQ 227

Query: 619 KGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA 678
           + +         K APG+  L G  G  G+ G PG  G +GE G QG+ G  G KGE G 
Sbjct: 228 RADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGL 287

Query: 679 TGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQG----------IQG 728
            G+PG PG  G  G QG+KG+ G  G KG +G+KGE G  G PG  G          + G
Sbjct: 288 PGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPG 347

Query: 729 HHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQP------------------G 770
             G KGE+G+ G PG  G  G  GE G  G  GP G KGQ                   G
Sbjct: 348 EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG 407

Query: 771 DPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIP 830
            PGP GPPG  G PG   +                            D    + G+ G  
Sbjct: 408 APGPSGPPGSVGAPGLRGTP-------------------------GKDGERGEKGAAGEE 442

Query: 831 GPPGPIGPEGPRGLPGLP-----GRDGVPGLVGVPGRPGV------RGLKGLPGRNGEKG 879
           G PGP+GP G  G PGLP     G+DG PGL G PG PG       RG  G+PG  G +G
Sbjct: 443 GSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG 502

Query: 880 SQGFGYPGEQGPPGPPGPEGPPG------------------------------ISKE--- 906
             G G  G  GP GPPG +G PG                              ++K+   
Sbjct: 503 DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCN 562

Query: 907 ----GPPGDPGLPGKDGDHGKPGIQGQ---------------PGPPGICDP 938
               GPPG PGLPG  GD G PG  G+               PGPPGI  P
Sbjct: 563 DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 613



 Score =  176 bits (445), Expect = 1e-43
 Identities = 113/301 (37%), Positives = 136/301 (45%), Gaps = 57/301 (18%)

Query: 650 GTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQ 709
           GT G    + +     +  A    G     G PGE G  GLPG  G +G+ G QG  G  
Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279

Query: 710 GQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQP 769
           G+KGE G  G PG  G++G  G +GE+GE G PG++G  G KGE+G      PAGP G P
Sbjct: 280 GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAG------PAGPPGLP 333

Query: 770 GD----------PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDH 819
           G           PG QGP G  G PG                   LP             
Sbjct: 334 GTTSLFTPHPRMPGEQGPKGEKGDPG-------------------LP------------- 361

Query: 820 CLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKG 879
                G PG+ G PG +GP+GP G PG  G++G  G  G  G PG  G  G PG +G  G
Sbjct: 362 -----GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG 416

Query: 880 SQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
           S   G PG +G PG  G  G  G +  G  G PG  G  GD G PG+ G PG     +P 
Sbjct: 417 S--VGAPGLRGTPGKDGERGEKGAA--GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPG 472

Query: 940 L 940
           L
Sbjct: 473 L 473


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  419 bits (1078), Expect = e-117
 Identities = 247/592 (41%), Positives = 300/592 (50%), Gaps = 76/592 (12%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            +PG  GE   GP  +  +P P       PG  GP G PG  G+PG PG  G+ G  G  G
Sbjct: 1028 LPGQRGE--EGPPGMRGSPGP-------PGPIGPPGFPGAVGSPGLPGLQGERGLTGLTG 1078

Query: 483  IAGTPGVPGSPGIQGARG---LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKG 539
              G PG PG PG  GA G   LPG KGE G  G  G++G PG PG  G+PG  G  G +G
Sbjct: 1079 DKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRG 1138

Query: 540  DKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGL------MGSPGFKGEAGSPG 593
            ++G  G  G+KG +G +G  GFPG PGP G PG+ G  G        GS G +G +G PG
Sbjct: 1139 ERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPG 1198

Query: 594  APGQ------------DGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG 641
            +PG             DG  G+ G PG  G+ G  G  G +GPPG +GK G PG+PG  G
Sbjct: 1199 SPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKG 1258

Query: 642  SNGSPGQPGTPGSKGSKGEPGI---QGMPG--------------------ASGLKGEPGA 678
              G PG PG+ G  G++GEPG    QG PG                    A GLKG+ GA
Sbjct: 1259 DCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGA 1318

Query: 679  TGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI---PGQQGIQGHHGAKGE 735
            TG  G  G  G PG  G  G  G  G  G  G++G  G+QG    PG +G  G  G KG+
Sbjct: 1319 TGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQ 1378

Query: 736  RGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGR-------EF 788
             GEKG  G+ G  G  G  G  G  GPAG +G PG PGP G PGL G PG        + 
Sbjct: 1379 AGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDE 1438

Query: 789  SEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLP 848
             ++FIRQ    +   ++       +       +    +PG PGPPG    +G  G PG P
Sbjct: 1439 IKRFIRQEIIKMFDERMAYYTSRMQFP-----MEMAAAPGRPGPPGK---DGAPGRPGAP 1490

Query: 849  GRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGP 908
            G  G+PG +G  GR G+ G++GLPG  GEKG  G G  GE G PGPPGP+GPPG  K G 
Sbjct: 1491 GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGA 1550

Query: 909  PGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPF-----RKGP 955
             G  G  G  G  G PG  GQPG  G C+PS CF  +     +      KGP
Sbjct: 1551 TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGP 1602



 Score =  379 bits (974), Expect = e-105
 Identities = 280/817 (34%), Positives = 356/817 (43%), Gaps = 169/817 (20%)

Query: 265 LSELTSNVFPEGLPPSYVFVSTQRFKV---KKIWDLWRILTIDGRPQIAVTLNGVDKILL 321
           +++ T  VFP GLP  +  V T   K    +K W L+++   +G PQI++ +N  ++ L 
Sbjct: 84  VTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQERSLE 143

Query: 322 FTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIENKPLHPVLGI 381
                         F  PQ   LFD  WH++ L V  +  ++++D     ++PL P   +
Sbjct: 144 LRAQGQDGDFVSCIFPVPQ---LFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRRPM 200

Query: 382 LINGQTQIGKYSGKEETVQFDVQKLRIY------------------CDPEQN-------- 415
              G   +G  + + + V FD+Q++ IY                  C PE +        
Sbjct: 201 RPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDTQS 260

Query: 416 -------------------------NRETACEIPGFNGECLNGPSDVGSTPAPCICPPGK 450
                                    N E   ++ G   +     + V    A   CPP  
Sbjct: 261 NELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCV 320

Query: 451 PGLQ---------GPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVP----------- 490
            G +         GPKG  G  G PG PG  G+ G  G   +  +P  P           
Sbjct: 321 HGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEK 380

Query: 491 GSPGIQGARGLPGYKGEPGRDGDKGD---RGLPGFPGLHGMPGSKGEMGAKGDKGSPGFY 547
           G  G  G  GLPG  GE G+ G+KGD   +G+PG PG  G PG    +G KG KG PGF 
Sbjct: 381 GESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFV 440

Query: 548 GKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIP 607
           G +G  GE G  G PG PG  G PG  G  G  G PG KG+ GS G PG++G  G+PG P
Sbjct: 441 GPEGLAGEPGPPGLPGPPG-IGLPGTPGDPG--GPPGPKGDKGSSGIPGKEGPGGKPGKP 497

Query: 608 GFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSP----GQPGTPGSKGSKGEP-- 661
           G  G +G   +     P G Q   G PG PG  G  G P    G PG  G KG KGEP  
Sbjct: 498 GVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCL 557

Query: 662 GIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIP 721
               + GA  L    GA+G  G PG+ GLPG+ G+ G  G +GEKG  G+ G  G  G P
Sbjct: 558 SCSSVVGAQHLVSSTGASGDVGSPGF-GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPP 616

Query: 722 GQQGIQGHHGAKGE------------------------RGEKGEP-----GVRGAIGSKG 752
           G  G  G  GAKGE                         GEKGEP     G+ G  G  G
Sbjct: 617 GPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAG 676

Query: 753 ESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSG 812
           E G+ G  G AG  G PG PG  G PGL G+PG                  Q P   +  
Sbjct: 677 ERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPG-----------------VQGPAGPKGE 719

Query: 813 RIRNCDHCLSQHGS----PGIPGPPGPIGPEGPRGL--PGLPGRDGVPGLVGVPGRPGVR 866
           +   C  C S  G+     G PG PGP G +GP G+  PG PG+ G+PG+ G PG  GV+
Sbjct: 720 KGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQ 779

Query: 867 GLKGLPGR-----NGEKGSQGF----GYPGEQGPPGP---------------PGPEGPPG 902
           G  G PGR      GE G+ G     G PG +GPPGP                GP GPPG
Sbjct: 780 GEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPG 839

Query: 903 ISKEGPPGDPGLPGKDGDHGKP---GIQGQPGPPGIC 936
            S  GPPG  G  G+ G  G P   G +G+ G PG C
Sbjct: 840 ASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGEC 876



 Score =  361 bits (927), Expect = 2e-99
 Identities = 228/613 (37%), Positives = 273/613 (44%), Gaps = 117/613 (19%)

Query: 412  PEQNNRETACEIPGFNGECLNGPSDVGSTPAPCICP----------PGKPGL-------Q 454
            P ++ ++    + G  GE   GP      P  C CP          PG PGL        
Sbjct: 846  PGRDGQQGQTGLRGTPGE--KGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQP 903

Query: 455  GPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPG----------------IQGA 498
            GP+G PG+PG PG PG PG  G PG  G+ G PG+    G                +QG 
Sbjct: 904  GPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQ 963

Query: 499  RGLPGYKGEPGRDGDKGDRGLPGFPGLH-------------------------------- 526
            R  PGY  E G   +KGD+G+PG PGL                                 
Sbjct: 964  RAHPGYLVEKG---EKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSP 1020

Query: 527  GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586
            G+PG  G  G +G++G PG  G  G  G  G  GFPG  G  G PG  G+ GL G  G K
Sbjct: 1021 GLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDK 1080

Query: 587  GEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS- 645
            GE G PG PG  G  G PG+PG  G RG  G  GE G PG  G +G PG PG  G  G  
Sbjct: 1081 GEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGER 1140

Query: 646  -----------------------PGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
                                   PG PG PG  GS G PG Q   G+ G++G  G  GSP
Sbjct: 1141 GPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSP 1200

Query: 683  GEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEP 742
            G PG  G+ G  G  G  G  G+ G++G  G  G  G+ G  G +G  G  G  G KG+ 
Sbjct: 1201 GPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDC 1260

Query: 743  GVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIR 802
            G  G  GS G  G +G  G  GP+G+PG PG  GPPG  G+PG                 
Sbjct: 1261 GKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGP---------------A 1305

Query: 803  AQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGR 862
                V L+  R    +  L+  G PG PGPPG  GP G  G  G  G++G PG  G  G 
Sbjct: 1306 GISAVGLKGDRGATGERGLA--GLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGP 1363

Query: 863  PGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDH 921
            PG +G  G  G+ G+ G +G  G PG  G  G  GP GPP     GP G+ G PG  G  
Sbjct: 1364 PGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPP-----GPAGERGHPGAPGPS 1418

Query: 922  GKPGIQGQPGPPG 934
            G PG+ G PG  G
Sbjct: 1419 GSPGLPGVPGSMG 1431



 Score =  338 bits (868), Expect = 1e-92
 Identities = 253/670 (37%), Positives = 300/670 (44%), Gaps = 188/670 (28%)

Query: 424  PGFNGE----CLNGPS----DVGST-PAPCICPPGKPGLQGPKGDPGLPGNPGYPGQP-- 472
            PG +G     C+ GP     D G   P      PG PGL GP G  GLPG PG PG P  
Sbjct: 416  PGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPG 474

Query: 473  --GQDGKPGYQGIAGTPGVPGSPGIQGARGLP------------GYKGEPGRDGDKGDRG 518
              G  G  G  G  G  G PG PG++G +G P             + G PG+ G KG+ G
Sbjct: 475  PKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPG 534

Query: 519  LP----GFPGLHGMPGSKGE-----------------MGAKGDKGSPGFY-----GKKGA 552
             P    G PG+ G+ G KGE                  GA GD GSPGF      G+ G 
Sbjct: 535  DPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGV 594

Query: 553  KGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSP---------------GAPGQ 597
             G KG  G  G  GPAG PG  G  G  G  G KGE   P                 PG 
Sbjct: 595  PGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGP 654

Query: 598  DGTRGEPGIPGF--------PGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP 649
             G +GEPG PGF         G RGL GQKG+ G PG  G  G  G PGL   +G PG  
Sbjct: 655  SGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGL---SGEPGVQ 711

Query: 650  GTPGSKGSKGE-----PGIQGM-------PGASGLKGEPG--ATGSPGEPGYMGLPGIQG 695
            G  G KG KG+     P +QG        PG  G KGE G    G PG+PG  GLPG+QG
Sbjct: 712  GPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQG 771

Query: 696  KKGDKGNQGE-----KGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKG---EPGVRGA 747
              G KG QGE     +G+QG +GE G  G+PG QG+ G  G  G  GEKG    PGV+GA
Sbjct: 772  PPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGA 831

Query: 748  IGSKGESGVDGLMGPAGPKGQPGD------PGPQGPPGLDGKPGREFSEQFIRQVCT--- 798
             G  G  G   + GP G  GQ G       PG +GP G  G+PG           C+   
Sbjct: 832  TGPVGPPGAS-VSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGE----------CSCPS 880

Query: 799  --DVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI-------PGPPGPIGPEGPRGLPGLPG 849
              D+I + +P                  G+PG+       PGP GP G  GP G PG+PG
Sbjct: 881  QGDLIFSGMP------------------GAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPG 922

Query: 850  RDGVPGLVGVPGRPGVRG-----------LKGLPGR--NGEKGSQGF----GYPGEQGPP 892
              GVPG  G+PG+PG+             LK + G    G++   G+    G  G+QG P
Sbjct: 923  LQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIP 982

Query: 893  GPPG-----------------------PEGPPG-ISKEGPPGDPGLPGKDGDHGKPGIQG 928
            G PG                        EG PG +   G PG PGLPG+ G+ G PG++G
Sbjct: 983  GVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRG 1042

Query: 929  QPGPPGICDP 938
             PGPPG   P
Sbjct: 1043 SPGPPGPIGP 1052



 Score =  335 bits (859), Expect = 1e-91
 Identities = 238/628 (37%), Positives = 285/628 (45%), Gaps = 142/628 (22%)

Query: 431  LNGPS-DVGSTPAPCICPPGKPG------LQGPKGDPGLPGNPGYPG---QPGQDGKPGY 480
            L GPS + G    P    PGK G      L+G KGD G PG+PG PG   +PG  G+PG 
Sbjct: 651  LPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGV 710

Query: 481  QGIAGTPGVPGS-----PGIQGA-RGLPGYKGEPGRDGDKGDRGL--PGFPGLHGMPGSK 532
            QG AG  G  G      P +QG    + G  G+PG  G++G  G+  PG PG  G+PG +
Sbjct: 711  QGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQ 770

Query: 533  GEMGAKGDKGSPGFYGK--KGAKGEKGNAGFPG---LPGPAGEPGRHGKDGLMGSPGFKG 587
            G  G KG +G PG  G+  +G +GE G  G PG   LPGP G PG  G+ G  GSPG KG
Sbjct: 771  GPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKG 830

Query: 588  EAGS---PGA-----PGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPG--QQGK---KGAP 634
              G    PGA     PG+DG +G+ G+ G PG +G  G+KGE G      QG     G P
Sbjct: 831  ATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMP 890

Query: 635  GMPGL-MGSN------------GSPGQPGTPGSKGSKGEPGIQGMPG------------- 668
            G PGL MGS+            G PG PG PG +G  G  G+ G PG             
Sbjct: 891  GAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQH 950

Query: 669  ---------ASGLKGEPGATGSPGEPGYMGLPGIQGKK---------------------- 697
                       G +  PG     GE G  G+PG+ G                        
Sbjct: 951  LLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNS 1010

Query: 698  -------GDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGS 750
                   G  G  G  G+ GQ+GE G  G+ G  G  G  G  G  G  G PG+ G  G 
Sbjct: 1011 EGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGE 1070

Query: 751  KGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQ 810
            +G +G+ G  G  GP GQPG PG  GPPGL G  G                R       +
Sbjct: 1071 RGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGE---------------RGYTGSAGE 1115

Query: 811  SGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGL---------PGLPGRDGVPGLVGVPG 861
             G            GS G+PGPPGP GP G RG           G  G+ G PG  G PG
Sbjct: 1116 KGE-------PGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPG 1168

Query: 862  RPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGPPGI----SKEGPP---G 910
             PG  G  G PG   EKGS+G     G PG  GPPGPPG +GP G+     K+G P   G
Sbjct: 1169 FPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRG 1228

Query: 911  DPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            DPG  G  G  G PG +G+ G PG+  P
Sbjct: 1229 DPGPAGPPGLMGPPGFKGKTGHPGLPGP 1256



 Score =  110 bits (275), Expect = 6e-24
 Identities = 86/244 (35%), Positives = 104/244 (42%), Gaps = 52/244 (21%)

Query: 726 IQGHHGAKGERGEKGE---------PGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776
           + G    K ERG K           P V GA  S      +  + P+GPKG  G+ G  G
Sbjct: 293 LTGRISQKAERGAKVHQETAADECPPCVHGARDS------NVTLAPSGPKGGKGERGLPG 346

Query: 777 PPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI 836
           PPG  G+ G   +         D +R      LQ              G  G  G  GP 
Sbjct: 347 PPGSKGEKGARGN---------DCVRISPDAPLQCAE--------GPKGEKGESGALGPS 389

Query: 837 GPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKG---LPGRNGEKGSQGF-GYPGEQGPP 892
           G  G  G  G  G  G  G+ GVPG+PG  G  G   + G  G+KG  GF G  G  G P
Sbjct: 390 GLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEP 449

Query: 893 GPPGPEGPPGISKEGPPGDPG-------------LPGKDGDHGKPG---IQGQPGPPGIC 936
           GPPG  GPPGI   G PGDPG             +PGK+G  GKPG   ++G+ G P   
Sbjct: 450 GPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEV 509

Query: 937 DPSL 940
            P+L
Sbjct: 510 CPTL 513


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  414 bits (1063), Expect = e-115
 Identities = 237/573 (41%), Positives = 296/573 (51%), Gaps = 58/573 (10%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPG-YQG 482
           PG  G    GP      P P +  PG+ G++GPKGDPG  G  G PG PG+ G+PG  QG
Sbjct: 110 PGLPGPGFAGPP---GPPGP-VGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQG 165

Query: 483 IAGT----------PGVPGSPGIQGARGL---------PGYKGEPGRDGD---KGDRGLP 520
           + G+          PG+ G PG+QG +G          PG++G+PG  GD    G++G+P
Sbjct: 166 LEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIP 225

Query: 521 GFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGA------------------KGEKGNAGFP 562
           G PG  G+ G  G  G KG+ G  G+ G  GA                   GEKG+ G P
Sbjct: 226 GPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSP 285

Query: 563 GLPGP---------AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNR 613
           G+ GP          G PG +GKDG  G+PG KG AG  G PG  G +G  G+PG PG +
Sbjct: 286 GIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTK 345

Query: 614 GLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLK 673
           G  G +GE GP G  G  G PG  G  G  G  G  G  G KG +GE G  G PG  G +
Sbjct: 346 GGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQ 405

Query: 674 GEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAK 733
           G  G  G PG PG  GLPG++G KG  G  G +G  G  G  G  G  G++G  G  G K
Sbjct: 406 GPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPK 465

Query: 734 GERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFI 793
           G++G +GEPG  G  G  G  GV G  GP GP+G  G+ G  G PG  G  GR+ ++Q I
Sbjct: 466 GQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHI 525

Query: 794 RQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGV 853
             V   +++ QL  +  S +       L   G  G PGPPGP G  G +G  G PG  GV
Sbjct: 526 VDVALKMLQEQLAEVAVSAK----REALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGV 581

Query: 854 PGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPG 913
           PG+VG  G+ G  G KG  G  G+ G  G G+PG  GPPG PG  G PG +  G  GD G
Sbjct: 582 PGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRG 641

Query: 914 LPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIA 946
            PG  G+ G+PG+ G  G PG C+P+ C    A
Sbjct: 642 SPGAPGEAGRPGLPGPVGLPGFCEPAACLGASA 674



 Score =  352 bits (902), Expect = 1e-96
 Identities = 210/509 (41%), Positives = 248/509 (48%), Gaps = 64/509 (12%)

Query: 453 LQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDG 512
           ++GP G+ G PG PG PG PG DG            + G  G  G  G PG KGEPG+ G
Sbjct: 25  IRGPPGERGPPGPPGPPGVPGSDG------------IDGDNGPPGKAGPPGPKGEPGKAG 72

Query: 513 DKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPG 572
             G  G PG  GL G  G  G MG  G KG PG  G  G  G  G AG PG PGP G PG
Sbjct: 73  PDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG-PGFAGPPGPPGPVGLPG 131

Query: 573 RHGKDGLMGSPGFKGEAGSPGAPGQDGTRG-----------------EPGI---PGFPGN 612
             G  G  G PG  G +G PG PG+ G  G                  PG+   PG  G 
Sbjct: 132 EIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGV 191

Query: 613 RGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGL 672
           +G  G++G +G PG QGK G  G  G  G  G PG PG  G +G  G  G +G  G  G 
Sbjct: 192 KGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGY 251

Query: 673 KGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGA 732
           KG  GA G+ G PG  G  G  G+ G+KG++G  GI+G +G  G +G  G  GI G  G 
Sbjct: 252 KGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGT 311

Query: 733 KGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGD---PGPQGPPGLDGKPGREFS 789
            G  G KG  G  G  GS G  G+ G+ G  G KG PGD   PGPQG PG  G PG+E  
Sbjct: 312 PGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGE 371

Query: 790 EQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPG 849
                ++    I                       G  G  G  GP+G  GP+G  G  G
Sbjct: 372 PGPRGEIGPQGIM----------------------GQKGDQGERGPVGQPGPQGRQGPKG 409

Query: 850 RDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG----FGYPGEQGPPGPPGPEGPPGISK 905
             G PG+ G  G PGV+G KG PG+ G +G  G     G PGE+G  G  G  GP G  +
Sbjct: 410 EQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKG--Q 467

Query: 906 EGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           +G  G+PG PG  GD G PG+QG PGPPG
Sbjct: 468 QGVRGEPGYPGPSGDAGAPGVQGYPGPPG 496



 Score =  107 bits (267), Expect = 5e-23
 Identities = 68/168 (40%), Positives = 77/168 (45%), Gaps = 19/168 (11%)

Query: 807 VLLQSGRIRNCDHCLSQHGSPGIP------------GPPGPIGPEGPRGLPGLPGRD--- 851
           V+L   +IR         G PG P            GPPG  GP GP+G PG  G D   
Sbjct: 18  VVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPD 77

Query: 852 ---GVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPG-ISKEG 907
              G+ GL G  G PG  G+ G+ G+ G  G  G   PG  GPPGPPGP G PG I   G
Sbjct: 78  GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRG 137

Query: 908 PPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGP 955
           P GDPG  G  G  G PG  G+PG     + S  F       P  KGP
Sbjct: 138 PKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGP 185



 Score =  107 bits (267), Expect = 5e-23
 Identities = 78/228 (34%), Positives = 87/228 (38%), Gaps = 71/228 (31%)

Query: 449 GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPG---------VPGSPGIQGAR 499
           G+ G  GPKG  G+ G PGYPG  G  G PG QG  G PG         VPG PG QG  
Sbjct: 457 GESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVE 516

Query: 500 GL---------------------------------------------PGYKGEPGRDGDK 514
           G                                              PGY G+ G  G  
Sbjct: 517 GRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHP 576

Query: 515 GDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGK--KGAKGEKGNAGFPGLPGPA---- 568
           G RG+PG  G  G  G+ G  G +G+KG PG  G+   G  G  G  G PG PG A    
Sbjct: 577 GPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGK 636

Query: 569 ----------GEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTR-GEPG 605
                     GE GR G  G +G PGF   A   GA      R  EPG
Sbjct: 637 DGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARLTEPG 684



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 8/74 (10%)

Query: 434 PSDVG----STPAPCICP--PGKPG--LQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAG 485
           P +VG      P P   P  PG+PG  + G  GD G PG PG  G+PG  G  G  G   
Sbjct: 606 PGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCE 665

Query: 486 TPGVPGSPGIQGAR 499
                G+     AR
Sbjct: 666 PAACLGASAYASAR 679


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  413 bits (1062), Expect = e-115
 Identities = 260/596 (43%), Positives = 293/596 (49%), Gaps = 97/596 (16%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGN--PGYPGQPGQDGKPGYQ 481
            PG  G  + GP      P P I  PG  G+ G KGDPG PG   PG PG+ G  G PG  
Sbjct: 813  PGLPGIGVQGPPGPPGIPGP-IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAP 871

Query: 482  GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDK 541
            G  G PG PG PG  GA G PG KGE G  G  G  G  G PG  G+PG KG+ G +G  
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931

Query: 542  GSPGFYGKKGAKGE-----------------KGNAGFPGLPGPAGEPGRHGKDGLMGSPG 584
            G PG  G+KG+KGE                 KG  G PGLPG  G  G  G  GL G PG
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPG 991

Query: 585  FKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNG 644
              G +G PG PG  G +G PG+PG PG  G  G KG IG  G  G +G  G PG  G  G
Sbjct: 992  QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 645  SPGQPGTPGSKGSKGEPGIQ--GMPGASGLKGEPGATGSPGEPGYM------GLPGIQGK 696
             PG PG PG KG KG+PGI   G+PG  G KGEPG  G PG PG        GLPG+ G 
Sbjct: 1052 QPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111

Query: 697  KGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGV 756
             G KG  G  G  G  G  G +GI G  G  G  G  G  G  G PG  G  G KG+ G 
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 757  DGLMGPAGPKGQPGDP--GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
            DG+ GPAG KG+PG P  G  GPPGL G  G++                 LP +  +  +
Sbjct: 1172 DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD-------------GGLPGIPGNPGL 1218

Query: 815  RNCDHCLSQHGSPGIPGPPGP--------------IGPEGPRGLPGLPGRDGVPGL---- 856
                     HG PG+ GPPGP               GP+GP G PGLPG +G PGL    
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNG 1278

Query: 857  -----VGVPGRPGVRGLKGL---------------PGRNGEKGSQGF----GYPGEQGP- 891
                  G PG+PG+ GL GL               PG NG KG  G     G+PG +GP 
Sbjct: 1279 GIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPS 1338

Query: 892  --PGPPGPEGPPGISKEGPPGDPGLPGKD-------GDHGKPGIQGQPGPPGICDP 938
              PG  GPEG PG+   GPPG PGLPG         GD G PGI GQPG  G+  P
Sbjct: 1339 GVPGSAGPEGEPGLI--GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP 1392



 Score =  409 bits (1050), Expect = e-114
 Identities = 256/572 (44%), Positives = 291/572 (50%), Gaps = 81/572 (14%)

Query: 422  EIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQ 481
            ++PG  GE   G   +   P P I PPG PGL G  G  G PG  G  G  G  G PG  
Sbjct: 854  DVPGPPGE--RGSPGIPGAPGP-IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 482  GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLH--GMPGSKGEMGAKG 539
            GI G  GVPG  G  G +G PG  G  G  G KG+ GLPG PG     + GSKGE G  G
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 540  DKGSPGFYGKKGAKGEKGNAGFPGL---------PGPAGEPGRHGKDGLMGSPGFKGEAG 590
              G PG  G KG +G  G+ G PGL         PGP G PG  G+ GL+G PG KG  G
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 591  SPGAPGQDGTRGEPG---IPGFPGNRGLMGQKGE--------IGPPGQQGKKGAPGMPG- 638
              G PG  G  G PG   +PG PG+ GL GQKG+        IG PG  G KG PG+PG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 639  -----LMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA------SGLKGEPGATGSPGEPG- 686
                 + GS G PG PG PG+ G+KG+PG+ G PG        G+ G PG  G PGEPG 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150

Query: 687  -----YMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI--PGQQGIQGHHGAKGERGEK 739
                 + G PG  G+KG  G  G  G  GQKGE G+ G   PG  G+ G  G KG+ G  
Sbjct: 1151 VGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 740  GEPGVRGAIGSKGESGVDG---LMGPAGPKGQPG--------DPGPQGPPGLDGKPGREF 788
            G PG  G  G KGE G  G   + GP GP G PG        +PGPQGPPG  G PG E 
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEG 1270

Query: 789  SEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLP 848
                             P L  +G I+         G PG+PG PG  G +GP GL G P
Sbjct: 1271 P----------------PGLPGNGGIKGEK---GNPGQPGLPGLPGLKGDQGPPGLQGNP 1311

Query: 849  GRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGIS--- 904
            GR G+ G+ G PG PGV G  G+ G +G  GS G  G PG  GPPGPPG  GP G S   
Sbjct: 1312 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1371

Query: 905  --KEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                GPPG PG PG  G  G  G QG PGP G
Sbjct: 1372 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1403



 Score =  407 bits (1045), Expect = e-113
 Identities = 252/578 (43%), Positives = 292/578 (50%), Gaps = 93/578 (16%)

Query: 434  PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQ---DGKPGYQGIAGTPGVP 490
            P   GS   P I   G PG  GPKG PG+PG PG PG PG+   +G PG  G  G  G P
Sbjct: 692  PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP 751

Query: 491  G--SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFP---GLHGMPGSKGEMGAKGDKGSPG 545
            G   PG  G  GLPG+KG  G  GD+G  G PG P   GL G+PG KG++G  G  G  G
Sbjct: 752  GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811

Query: 546  FYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDG-----------LMGSPGFKGEAGSPGA 594
              G  G  G +G  G PG+PGP G+PG HG  G           + G PG +G  G PGA
Sbjct: 812  PPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870

Query: 595  PGQDGTRGEPGIP------GFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQ 648
            PG  G  G PG+P      GFPG +G MG  G  GPPG  G  G  G+PGL G +G  GQ
Sbjct: 871  PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQ 930

Query: 649  PGTP--------------------------GSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
            PG P                          GSKG KGEPG+ G+PG SG KG  G  G P
Sbjct: 931  PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990

Query: 683  GEPGYMGLPGIQGKKGDKGNQGEK------GIQGQKGENGRQGIPGQQGIQGHHGAKGER 736
            G+PG  G PG+ G  G KGN G        G  G KG  G  G PG QG++G  G  G  
Sbjct: 991  GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP 1050

Query: 737  GEKGEPGVRGAIGSKGESGVD--GLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIR 794
            G+ G PG+ G  G KG+ G+   GL G  GPKG+PG PG  G PG+ G  G         
Sbjct: 1051 GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG--------- 1101

Query: 795  QVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVP 854
                      LP L  +   +         G PG PGPPGP G  GP G PGLPG  G  
Sbjct: 1102 -------DPGLPGLPGTPGAKGQP---GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 855  GLVGVPGRPGVRGLKGLPGRN---------GEKGSQGFGYPGEQGPPGPPGPEGPPGISK 905
            G  G PG+PG  G KG PG++         GE G  GFG PG  G PG  G +G  G+  
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL-- 1209

Query: 906  EGPPGDPGLPGKDGD---HGKPGIQGQPGPPGICDPSL 940
             G PG+PGLPG  G+   HG PG+QG PGPPG   P+L
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247



 Score =  402 bits (1034), Expect = e-112
 Identities = 254/574 (44%), Positives = 291/574 (50%), Gaps = 99/574 (17%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPG----------------YQGIAGTPGVPGS 492
            G+ G  GPKG PG+PG PG PG PG  G+PG                  G  G PG+PG+
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 493  PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGA 552
            PG  G  GLPG KGEPG    KG+RG PG PGL G+PG+ G MG  G  G PG  G+KG 
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGI 636

Query: 553  KGEKGNAGFPGLPGPAGEPG----RHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPG 608
            +G  GN G PG+PGP G+PG    + GK GL G+PG  G+ G PG PG  G  G PGIPG
Sbjct: 637  QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG 696

Query: 609  FPGNR-----GLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGS------ 657
              G       GL G  G  G PG  G  GAPG PG +G  G PG PG PG KG       
Sbjct: 697  SKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP 756

Query: 658  --KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQ---- 711
               G PG+ G  GA G KG+ G  G PG PG  GL G+ G KGD G  G+ G  G     
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 712  ----KGENGRQGIPGQQGIQGHHGAKGERGEKGEPG--VRGAIGSKGESGVDGLMGPAGP 765
                +G  G  GIPG  G  G HG  GE+G+ G PG  V G  G +G  G+ G  GP GP
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 766  KGQPGDP------------------GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPV 807
             G PG P                  GP GPPG  G PGR            D ++ Q  +
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD---DGLQGQPGL 933

Query: 808  LLQSGRIRNCDHCLSQHGSPGIPGPPGP-----IGPEGPRGLPGLPGRDGV------PGL 856
               +G            G PG+PGPPGP     +G +G +G PGLPG  GV       GL
Sbjct: 934  PGPTGE-------KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986

Query: 857  VGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGP------------PGPPGPEGPPGI 903
             G PG+PG+ G  GLPG  G KG+ G  G PG  GP            PGP G EGPPG 
Sbjct: 987  PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046

Query: 904  S-KEGPPGDPGLPGKDGDHGKPGIQ--GQPGPPG 934
            S   G PG PGLPG+ GD G PGI   G PG PG
Sbjct: 1047 SGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  395 bits (1014), Expect = e-109
 Identities = 246/553 (44%), Positives = 281/553 (50%), Gaps = 91/553 (16%)

Query: 436 DVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQ---PGQDGKPGYQGIAGTPGVPGS 492
           D G T   CI      G+ GP G PGLPG PG PG    PGQ G+ G  G  G  G+PG 
Sbjct: 476 DKGDTCFNCI----GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 493 PGIQGARGLPGYKGE-------PGRDGDKGDRGLPGFPGLHGMPGSKGE---MGAKGDKG 542
           PG  GA G PG KGE       PG  GDKG+ G PG PGL G+PG+ G+    G  G KG
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 543 SPGFYGKKGAKGEKGNAGFPGLP---GPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDG 599
            PG    KG +G  GN G PGLP   GP G PG  G  G +G  G +G AG+PG PG  G
Sbjct: 592 EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 600 TRGEPG----IPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP--GTPG 653
            +G+PG     PG PG  G  G+ G++G PG  G  G PG+PG+ GS G PG P  G PG
Sbjct: 651 PKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPG 710

Query: 654 SKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMG--------LPGIQGKKGDKGNQGE 705
             G KG PGI G PGA G  G  G  G PG PG+ G        LPG  G  G  G +G 
Sbjct: 711 PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA 770

Query: 706 KGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGP 765
            G +G +G  G  G PG+ G+ G  G KG+ G  G+PG  G  G  G       +G  GP
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-------IGVQGP 823

Query: 766 KGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHG 825
            G PG PGP G PGL G PG +           D     L V    G          + G
Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEK----------GDPGPPGLDVPGPPG----------ERG 863

Query: 826 SPGIPGPPGPIGPEGPRGLPGLPGRDGVPGL---------------VGVPGRPGVRGLK- 869
           SPGIPG PGPIGP G  GLPG  G  G PG                +G+PGR GV GLK 
Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923

Query: 870 --------GLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDH 921
                   GLPG  GEKGS+     GE G PGPPGP  P  +  +G  G+PGLPG  G  
Sbjct: 924 DDGLQGQPGLPGPTGEKGSK-----GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS 978

Query: 922 GKPGIQGQPGPPG 934
           G  G QG PG PG
Sbjct: 979 GPKGYQGLPGDPG 991



 Score =  392 bits (1006), Expect = e-108
 Identities = 253/597 (42%), Positives = 289/597 (48%), Gaps = 96/597 (16%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPG-------------YPG 470
           PGF GE        G    P I  PG PGL G  G PGLPG PG              PG
Sbjct: 399 PGFPGE----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 471 QPGQDGKPGYQGIAGTPGV-------------------PGSPGIQGARGLPGYKGEPGRD 511
            PG  G PG +G+ G  GV                   PG PG+ G  G PG  G PG+ 
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 512 GDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPG----FYGKKGAKGEKGNAGFPGLPGP 567
           G+KG  G  G  GL G+PG+ G  G  G KG PG    F G KG KGE G+ G PGLPG 
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 568 AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQ 627
            G PG+   DGL G PG KGE G     G+ G  G PG+PG PGN G MG  G  GPPG 
Sbjct: 575 PGTPGQ---DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGP 630

Query: 628 QGKKGA------PGMPGLMGSNGSPGQ----PGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
            G+KG       PG PG+ G  G PGQ    PG PG  G+ G  G  G+PG  GL G+PG
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPG 690

Query: 678 ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             G PG  G  G+PGI    G  G  G KG  G  G  G  G PG+ G++G  G  G  G
Sbjct: 691 LPGIPGSKGEPGIPGI----GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 738 EKGEPG--VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQ 795
            KGEPG  + G  G  G  G  G +GP G +G PG PGP G  GLDG PG +        
Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPK-------- 798

Query: 796 VCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPG 855
              DV     P  +    +      +   G PG PG PGPIG  G  G+PG  G  G PG
Sbjct: 799 --GDVGPNGQPGPMGPPGLPG----IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852

Query: 856 L-----------VGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGP 900
           L            G+PG PG  G  G PG  G+ G+ GF    G  G  GPPGPPGP G 
Sbjct: 853 LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 901 PGIS-------KEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDP 950
           PG S        +G  G PGLPG  G+ G  G  G PGPPG  DP+L  S   + +P
Sbjct: 913 PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969



 Score =  385 bits (990), Expect = e-107
 Identities = 252/647 (38%), Positives = 301/647 (46%), Gaps = 152/647 (23%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGN------------------ 465
           PG  G  L GP+ +   P P I PPG PGL GP G PGLPG                   
Sbjct: 179 PGIQG--LPGPTGI---PGP-IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQ 232

Query: 466 -----PGYPGQ-------------------PGQDGKPGYQGIAGTPGVPGSP-GIQGARG 500
                PG PGQ                   PG  G PG  GI G PG PG   G +G +G
Sbjct: 233 GLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG 292

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAK------- 553
            PG +G+PG+DG+ G  G+PG PG  G PG  G  G KG KG  G  G  G         
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTG 352

Query: 554 ---GEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
              GEKGN G PGLPG  GE          G PG +G  G PG PG     G PG PGFP
Sbjct: 353 ITIGEKGNIGLPGLPGEKGE---------RGFPGIQGPPGLPGPPGA-AVMGPPGPPGFP 402

Query: 611 GNRGLMGQKGEIG-----PPGQQGKKGAPGMPGLMG-------------SNGSPGQPGTP 652
           G RG  G +G  G     PPG  G+ GAPG+PG  G               G PG PG+P
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 653 GSKGSKGEPGIQGMPG----------ASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN 702
           G KG +GE G++G  G           SG  G+PG  G PG PG +G PG +G+KG  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 703 QGEKGIQGQKGENGRQGIPGQQGIQGH----HGAKGERGEKGEPGVRGAIGSKGESGVDG 758
            G KG+ G  G  G  G PG +G  G      G KG++GE G PG  G  G  G  G DG
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 759 LMGPAGPKGQPG------DPGPQGPPGLDGKPGR-------------EFSEQFIRQVCTD 799
           L G  GPKG+PG      + GP G PGL G PG                 E+ I+ V  +
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 800 VIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGL--- 856
             +  +P     G   +    ++Q G PG+PG PG  G  G  G PGLPG+ G+PG+   
Sbjct: 643 PGQPGIP-----GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 857 --------VGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEG 907
                   +G+PG PG +G  G+PG  G  G+ G  G  G  GPPG PGP+G PG +  G
Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPG 757

Query: 908 PPGDP---------------GLPGKDGDHGKPGIQGQPGPPGICDPS 939
           PPG P               G PG  G  G+ G+ G PGP G   P+
Sbjct: 758 PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804



 Score =  377 bits (969), Expect = e-104
 Identities = 234/513 (45%), Positives = 256/513 (49%), Gaps = 68/513 (13%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICP-----PGKPGLQGPKGDPGLPGNPGYPGQPGQDGK 477
            +PG  G  ++GP      P     P     PG PG  GPKG+PGLPG PG  G PG  G 
Sbjct: 971  LPGIPG--VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 478  PGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRG-----LPGFPG------LH 526
             G  G  G  GV G PG  G  G PG  G PG+ GDKGD G     LPG PG      L 
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 527  GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586
            G PG+ G  G+ GD G PG  G  GAKG+ G  GFPG PGP G  G  G  G  G PG  
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148

Query: 587  GEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS- 645
            G  G  G PGQ G  GE G PG  G  G  GQKGE G PG  G  G PG+PGL G  G  
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDG 1207

Query: 646  --PGQPGTPGSKGSKGEPGIQGMPGASGL--------------KGEPGATGSPGEPGYMG 689
              PG PG PG  G KGEPG  G PG  G               KG PG  G PG PG  G
Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPG 1267

Query: 690  ------LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPG 743
                  LPG  G KG+KGN G+ G+ G  G  G QG PG QG  G  G  G +G+ G PG
Sbjct: 1268 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1327

Query: 744  VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRA 803
            V G  G KG SGV G    AGP+G+PG  GP GPPGL G  G+         +  D    
Sbjct: 1328 VPGFPGMKGPSGVPG---SAGPEGEPGLIGPPGPPGLPGPSGQSII------IKGDAGPP 1378

Query: 804  QLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRP 863
             +P                Q G  G+PGP GP G  GP G PG PGR+G+PG  G  GR 
Sbjct: 1379 GIP---------------GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRK 1423

Query: 864  GVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPG 896
            G  GL G PG  G  G    G  G QGPPGPPG
Sbjct: 1424 GDPGLPGQPGTRGLDGPP--GPDGLQGPPGPPG 1454



 Score =  375 bits (964), Expect = e-104
 Identities = 249/633 (39%), Positives = 287/633 (45%), Gaps = 140/633 (22%)

Query: 423 IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGL------------------PG 464
           +PG  G    GP  +   P P   P G+ G +G +G+PG                   PG
Sbjct: 262 LPGDRGP--PGPPGIRGPPGP---PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 465 NPGYPGQPGQDGKPGYQGIAGTPGVP-------------GSPGIQGARGLPGYKGEPGRD 511
           +PGYPG+PG+DG+ G +G  G PG P             G  G  G  GLPG KGE G  
Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 512 GDKGDRGLPGFPGL-----HGMPGSKGEMGAKGDKGSPGFY--GKKGAKGEKGNAGFPGL 564
           G +G  GLPG PG       G PG  GE G KGD+G PG    G  G  G+ G  G PG 
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436

Query: 565 PGPA----------------GEPGRHGKDGLMGSPGFKGE-------------AGSPGAP 595
           PGPA                G PG  G  GL G  G KG+             +G PG P
Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP 496

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSP--------- 646
           G  G  G PG  GFPG +G  GQ G  GP G  G  GAPG PG  GS G P         
Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 647 -------GQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA------TGSPGEPGYMGLP-- 691
                  G PG PG  G  G PG  G+PG  G KGEPG        G PG PG  GLP  
Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616

Query: 692 ---------------GIQGKKGDKGNQGEKGIQGQKG-------ENGRQGIPGQQGIQGH 729
                          G +G +G  GN G+ GI G KG       + G+ G+PG  G  G 
Sbjct: 617 IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 676

Query: 730 HGAKGERGEKGEPGVRGAIGSKGESGVD--GLMGPAGPKGQPGDPGPQGPPGLDGKPGRE 787
            G  G+ G  G+PG+ G  GSKGE G+   GL GP GPKG PG PGP G PG  G+ G E
Sbjct: 677 VGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE 736

Query: 788 FSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGL 847
                             P      +           G PG+PG  G +GP+G RG PG 
Sbjct: 737 GPPG--------------PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782

Query: 848 PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGI---- 903
           PG  G  GL G+PG  G  G  G PG  G  G  G G  G  GPPG PGP G PG+    
Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 904 SKEGPPGDPGL--PGKDGDHGKPGIQGQPGPPG 934
            ++G PG PGL  PG  G+ G PGI G PGP G
Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875



 Score =  370 bits (949), Expect = e-102
 Identities = 248/646 (38%), Positives = 292/646 (45%), Gaps = 172/646 (26%)

Query: 439 STPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSP---GI 495
           S  + C C  G  G +G +G PGL G+PG PG PG +G PG +G  G  G+PG P   GI
Sbjct: 33  SPGSKCDCS-GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGI 91

Query: 496 QGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGE 555
           +G  GLPG+ G PG  G  G  G PG  G+ G  G+KGE G  G  G PG  G  G  G 
Sbjct: 92  RGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 556 KGNAGFPG------LPGPAGEPGRHGKDGLMGSP---GFKGEAGSPGAPGQDGTRGEPGI 606
            G  G PG      LPGP G PG  G  G+ G P   G  G  G PG PG  G  G PG+
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL 211

Query: 607 PGFPGNRGL-----MGQKGE------IGPPGQ-------------------QGKKGAPGM 636
           PG  GN GL      G+KGE       GPPGQ                    G +G PG 
Sbjct: 212 PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 637 PGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGK 696
           PG+ G  G PG  G  G KG +GEPG +G PG  G  G+PG  G PG+PGY G PG  G+
Sbjct: 272 PGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 697 K-------------------------GDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG 731
           K                         G+KGN G  G+ G+KGE G  GI G  G+ G  G
Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 732 A-----------KGERGEKGE--------PGVRGAIGSKGESGVDGLMGPAGPKGQPGD- 771
           A            GERG+KG+        PG  G  G  G  G+ G  GPAGP   P D 
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 772 ---PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCL------- 821
              PGP GPPG  G  G +  EQ ++    D                 C +C+       
Sbjct: 450 ICEPGPPGPPGSPGDKGLQ-GEQGVKGDKGD----------------TCFNCIGTGISGP 492

Query: 822 -SQHGSPGIPGPPGPI------------GPEGPRGLPGLP-------------------- 848
             Q G PG+PGPPG +            G  GP+GLPG+P                    
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 849 -----------GRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPP-- 895
                      G  G PGL G+PG PG  GL GLPG  GE G  G  + GE+GPPG P  
Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG--GITFKGERGPPGNPGL 610

Query: 896 -------GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                  GP GPPG    GP G+ G+ G  G+ G+PGI G  G PG
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656



 Score =  338 bits (867), Expect = 1e-92
 Identities = 198/447 (44%), Positives = 229/447 (51%), Gaps = 58/447 (12%)

Query: 448  PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
            PG  G++GP G  G+PG PG PG PGQ G  G  GI+   G+PG PG +G  GLPGY G 
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI-GLPGLPGPKGEPGLPGYPGN 1093

Query: 508  PGRDGDKGDRGLPGFPG---------LHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGN 558
            PG  G  GD GLPG PG         L G PG+ G  G KG  G PG  G  G  G  G 
Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153

Query: 559  AGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPG--------APGQDGTRGEPGIPGFP 610
             G PG PGP GE G+ G+DG+ G  G KGE G PG         PG  G +G+ G+PG P
Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213

Query: 611  GNRGLMGQKGEIGP---PGQQGKKGAPGMPG--LMGSNGSPGQPGTPGSKGSKGEPGIQG 665
            GN GL G KGE G    PG QG  G PG PG  L G  G+PG  G PG  G  G  G  G
Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPG 1273

Query: 666  MPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQG 725
            +PG  G+KGE G  G PG PG  GL G QG  G +GN G  G+ G KG+ G  G+PG  G
Sbjct: 1274 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1333

Query: 726  IQGHHGAKGERGEKGEPGVRGAIGS-------------KGESGVDGLMGPAGPKGQPGDP 772
            ++G  G  G  G +GEPG+ G  G              KG++G  G+ G  G KG PG  
Sbjct: 1334 MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ 1393

Query: 773  GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGP 832
            GPQG PG  G PG             D  R  LP    +G          + G PG+PG 
Sbjct: 1394 GPQGLPGPTGPPG-------------DPGRNGLPGFDGAG---------GRKGDPGLPGQ 1431

Query: 833  PGPIGPEGPRGLPGLPGRDGVPGLVGV 859
            PG  G +GP G  GL G  G PG   V
Sbjct: 1432 PGTRGLDGPPGPDGLQGPPGPPGTSSV 1458



 Score =  295 bits (756), Expect = 1e-79
 Identities = 195/484 (40%), Positives = 226/484 (46%), Gaps = 100/484 (20%)

Query: 496 QGARGLPGYKGEPGR----DGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKG 551
           Q A     Y   PG      G KG++G  GFPGL G PG             PGF G +G
Sbjct: 22  QPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGL------------PGFPGPEG 69

Query: 552 AKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611
             G +G  G  G+PGP G  G  G  GL   PGF G  G PG PG DG  G  GIPG  G
Sbjct: 70  PPGPRGQKGDDGIPGPPGPKGIRGPPGL---PGFPGTPGLPGMPGHDGAPGPQGIPGCNG 126

Query: 612 NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS---PGQPGTPGSKGSKGEPGIQGMPG 668
            +G  G  G  G PG QG  G PG+PG+ G  GS      PG  G+ G  G PGIQG+PG
Sbjct: 127 TKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPG 186

Query: 669 ASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQG 728
            +G+   PG  G PG PG MG PG  G  G KGN G    QG KGE G      +QG+QG
Sbjct: 187 PTGI---PGPIGPPGPPGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKG------EQGLQG 236

Query: 729 HHGAKGERGEKGEP-------GVRGAIGSKGESGVDGLMGPAGPKG-QPGDPGPQGPPGL 780
             G  G+  E+  P       G +G  G +G  G  G+ GP GP G + G+ G QG PG 
Sbjct: 237 PPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 781 DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG 840
            GKPG++                                   ++G PGIPG PG  G  G
Sbjct: 297 RGKPGKD----------------------------------GENGQPGIPGLPGDPGYPG 322

Query: 841 PRGLPGLPGRDGVPGLVGVPG----RPGV------RGLKGLPGRNGEKGSQGFGYPGEQG 890
             G  G  G+ G  G  G PG    RPG       +G  GLPG  GEKG +GF  PG QG
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF--PGIQG 380

Query: 891 PPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQ--------------GQPGPPGIC 936
           PPG PGP G   +   GPPG PG  G+ GD G PGI               G PGPPG  
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 937 DPSL 940
            P +
Sbjct: 441 GPHI 444



 Score =  236 bits (603), Expect = 6e-62
 Identities = 130/274 (47%), Positives = 148/274 (54%), Gaps = 21/274 (7%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG---IAGTPGVPGSPG--IQGARGL 501
            PPG PGL G KGD GLPG PG PG PG  G+PG+ G   + G PG PGSPG  ++G +G 
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN 1253

Query: 502  PGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGF 561
            PG +G PGR G  G  G PG PG  G+ G KG  G  G  G PG  G +G  G +GN G 
Sbjct: 1254 PGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGR 1313

Query: 562  PGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQ--- 618
            PGL G  G+PG      L G PGF G  G  G PG  G  GEPG+ G PG  GL G    
Sbjct: 1314 PGLNGMKGDPG------LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ 1367

Query: 619  ----KGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKG 674
                KG+ GPPG  G+ G  G+PG  G  G PG  G PG  G  G PG  G   A G KG
Sbjct: 1368 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG---AGGRKG 1424

Query: 675  EPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
            +PG  G PG  G  G PG  G +G  G  G   +
Sbjct: 1425 DPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1458



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 17/36 (47%), Positives = 18/36 (50%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIA 484
            G PGL G  G  GL G PG  G  G  G PG   +A
Sbjct: 1424 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  410 bits (1055), Expect = e-114
 Identities = 246/543 (45%), Positives = 272/543 (50%), Gaps = 67/543 (12%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGN--PGYPGQPGQDGKPGYQ 481
            PG  G  + GP      P P I  PG  G+ G KGDPG PG   PG PG+ G  G PG  
Sbjct: 813  PGLPGIGVQGPPGPPGIPGP-IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAP 871

Query: 482  GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDK 541
            G  G PG PG PG  GA G PG KGE G  G  G  G  G PG  G+PG KG+ G +G  
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931

Query: 542  GSPGFYGKKGAKGE-----------------KGNAGFPGLPGPAGEPGRHGKDGLMGSPG 584
            G PG  G+KG+KGE                 KG  G PGLPG  G  G  G  GL G PG
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPG 991

Query: 585  FKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNG 644
              G +G PG PG  G +G PG+PG PG  G  G KG IG  G  G +G  G PG  G  G
Sbjct: 992  QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 645  SPGQPGTPGSKGSKGEPGIQ--GMPGASGLKGEPGATGSPGEPGYM------GLPGIQGK 696
             PG PG PG KG KG+PGI   G+PG  G KGEPG  G PG PG        GLPG+ G 
Sbjct: 1052 QPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111

Query: 697  KGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGV 756
             G KG  G  G  G  G  G +GI G  G  G  G  G  G  G PG  G  G KG+ G 
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 757  DGLMGPAGPKGQPGDP--GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
            DG+ GPAG KG+PG P  G  GPPGL G  G++                           
Sbjct: 1172 DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK--------------------------- 1204

Query: 815  RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                      G PGIPG PG  GP+G  G  G PG  G PG  G PG P + G KG PG 
Sbjct: 1205 -------GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGP 1256

Query: 875  NGEKGSQGF-GYPGEQGPPGPPGPEGPPG-ISKEGPPGDPGLPGKDGDHGKPGIQGQPGP 932
             G  G  GF G PG +GPPG PG  G  G     G PG PGLPG  GD G PG+QG PG 
Sbjct: 1257 QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGR 1316

Query: 933  PGI 935
            PG+
Sbjct: 1317 PGL 1319



 Score =  407 bits (1045), Expect = e-113
 Identities = 252/578 (43%), Positives = 292/578 (50%), Gaps = 93/578 (16%)

Query: 434  PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQ---DGKPGYQGIAGTPGVP 490
            P   GS   P I   G PG  GPKG PG+PG PG PG PG+   +G PG  G  G  G P
Sbjct: 692  PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP 751

Query: 491  G--SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFP---GLHGMPGSKGEMGAKGDKGSPG 545
            G   PG  G  GLPG+KG  G  GD+G  G PG P   GL G+PG KG++G  G  G  G
Sbjct: 752  GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811

Query: 546  FYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDG-----------LMGSPGFKGEAGSPGA 594
              G  G  G +G  G PG+PGP G+PG HG  G           + G PG +G  G PGA
Sbjct: 812  PPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870

Query: 595  PGQDGTRGEPGIP------GFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQ 648
            PG  G  G PG+P      GFPG +G MG  G  GPPG  G  G  G+PGL G +G  GQ
Sbjct: 871  PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQ 930

Query: 649  PGTP--------------------------GSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
            PG P                          GSKG KGEPG+ G+PG SG KG  G  G P
Sbjct: 931  PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990

Query: 683  GEPGYMGLPGIQGKKGDKGNQGEK------GIQGQKGENGRQGIPGQQGIQGHHGAKGER 736
            G+PG  G PG+ G  G KGN G        G  G KG  G  G PG QG++G  G  G  
Sbjct: 991  GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP 1050

Query: 737  GEKGEPGVRGAIGSKGESGVD--GLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIR 794
            G+ G PG+ G  G KG+ G+   GL G  GPKG+PG PG  G PG+ G  G         
Sbjct: 1051 GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG--------- 1101

Query: 795  QVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVP 854
                      LP L  +   +         G PG PGPPGP G  GP G PGLPG  G  
Sbjct: 1102 -------DPGLPGLPGTPGAKGQP---GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 855  GLVGVPGRPGVRGLKGLPGRN---------GEKGSQGFGYPGEQGPPGPPGPEGPPGISK 905
            G  G PG+PG  G KG PG++         GE G  GFG PG  G PG  G +G  G+  
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL-- 1209

Query: 906  EGPPGDPGLPGKDGD---HGKPGIQGQPGPPGICDPSL 940
             G PG+PGLPG  G+   HG PG+QG PGPPG   P+L
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247



 Score =  404 bits (1039), Expect = e-112
 Identities = 256/575 (44%), Positives = 291/575 (50%), Gaps = 84/575 (14%)

Query: 422  EIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQ 481
            ++PG  GE   G   +   P P I PPG PGL G  G  G PG  G  G  G  G PG  
Sbjct: 854  DVPGPPGE--RGSPGIPGAPGP-IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 482  GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLH--GMPGSKGEMGAKG 539
            GI G  GVPG  G  G +G PG  G  G  G KG+ GLPG PG     + GSKGE G  G
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 540  DKGSPGFYGKKGAKGEKGNAGFPGL---------PGPAGEPGRHGKDGLMGSPGFKGEAG 590
              G PG  G KG +G  G+ G PGL         PGP G PG  G+ GL+G PG KG  G
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 591  SPGAPGQDGTRGEPG---IPGFPGNRGLMGQKGE--------IGPPGQQGKKGAPGMPG- 638
              G PG  G  G PG   +PG PG+ GL GQKG+        IG PG  G KG PG+PG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 639  -----LMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA------SGLKGEPGATGSPGEPG- 686
                 + GS G PG PG PG+ G+KG+PG+ G PG        G+ G PG  G PGEPG 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150

Query: 687  -----YMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI--PGQQGIQGHHGAKGERGEK 739
                 + G PG  G+KG  G  G  G  GQKGE G+ G   PG  G+ G  G KG+ G  
Sbjct: 1151 VGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 740  GEPGVRGAIGSKGESGVDG---LMGPAGPKGQPG--------DPGPQGPPG---LDGKPG 785
            G PG  G  G KGE G  G   + GP GP G PG        +PGPQGPPG     G PG
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPG 1270

Query: 786  REFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLP 845
             E                  P L  +G I+         G PG+PG PG  G +GP GL 
Sbjct: 1271 PEGP----------------PGLPGNGGIKGEK---GNPGQPGLPGLPGLKGDQGPPGLQ 1311

Query: 846  GLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGIS 904
            G PGR G+ G+ G PG PGV G  G+ G +G  GS G  G PG  GPPGPPG  GP G S
Sbjct: 1312 GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQS 1371

Query: 905  -----KEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                   GPPG PG PG  G  G  G QG PGP G
Sbjct: 1372 IIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1406



 Score =  402 bits (1034), Expect = e-112
 Identities = 254/574 (44%), Positives = 291/574 (50%), Gaps = 99/574 (17%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPG----------------YQGIAGTPGVPGS 492
            G+ G  GPKG PG+PG PG PG PG  G+PG                  G  G PG+PG+
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 493  PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGA 552
            PG  G  GLPG KGEPG    KG+RG PG PGL G+PG+ G MG  G  G PG  G+KG 
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGI 636

Query: 553  KGEKGNAGFPGLPGPAGEPG----RHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPG 608
            +G  GN G PG+PGP G+PG    + GK GL G+PG  G+ G PG PG  G  G PGIPG
Sbjct: 637  QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG 696

Query: 609  FPGNR-----GLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGS------ 657
              G       GL G  G  G PG  G  GAPG PG +G  G PG PG PG KG       
Sbjct: 697  SKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP 756

Query: 658  --KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQ---- 711
               G PG+ G  GA G KG+ G  G PG PG  GL G+ G KGD G  G+ G  G     
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 712  ----KGENGRQGIPGQQGIQGHHGAKGERGEKGEPG--VRGAIGSKGESGVDGLMGPAGP 765
                +G  G  GIPG  G  G HG  GE+G+ G PG  V G  G +G  G+ G  GP GP
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 766  KGQPGDP------------------GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPV 807
             G PG P                  GP GPPG  G PGR            D ++ Q  +
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD---DGLQGQPGL 933

Query: 808  LLQSGRIRNCDHCLSQHGSPGIPGPPGP-----IGPEGPRGLPGLPGRDGV------PGL 856
               +G            G PG+PGPPGP     +G +G +G PGLPG  GV       GL
Sbjct: 934  PGPTGE-------KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986

Query: 857  VGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGP------------PGPPGPEGPPGI 903
             G PG+PG+ G  GLPG  G KG+ G  G PG  GP            PGP G EGPPG 
Sbjct: 987  PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046

Query: 904  S-KEGPPGDPGLPGKDGDHGKPGIQ--GQPGPPG 934
            S   G PG PGLPG+ GD G PGI   G PG PG
Sbjct: 1047 SGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  402 bits (1032), Expect = e-111
 Identities = 238/534 (44%), Positives = 273/534 (51%), Gaps = 95/534 (17%)

Query: 448  PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
            PG PG+ GPKG  GLPG+PG PG  GQ G PG  G  G PG+PG PG+ G  GL G  G+
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031

Query: 508  PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP 567
             G  G +G  G PG  G+ G PGS G  G KGDKG PG            + G PGLPGP
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI----------SSIGLPGLPGP 1081

Query: 568  AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQ 627
             GEPG  G  G  G  G  G+ G PG PG  G +G+PG+PGFPG  G  G KG  GPPG 
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141

Query: 628  QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGY 687
             G    PG PG +G  G PGQPG PG KG   +PG  G+PG +G KGEPG  G  G PG 
Sbjct: 1142 PG---LPGEPGPVGGGGHPGQPGPPGEKG---KPGQDGIPGPAGQKGEPGQPGF-GNPGP 1194

Query: 688  MGLPGIQGKKGD---KGNQGEKGIQGQKGENGRQGIPGQQG-----------IQGHHGAK 733
             GLPG+ G+KGD    G  G  G+ G KGE G  G PG QG           ++G  G  
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254

Query: 734  GERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPG---------PQGPPGLDGKP 784
            G +G  G PG +G  G +G  G+ G  G  G KG PG PG          QGPPGL G P
Sbjct: 1255 GPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1314

Query: 785  GREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGL 844
            GR                                      G PG+PG PG  G +GP G+
Sbjct: 1315 GRPGLN-------------------------------GMKGDPGLPGVPGFPGMKGPSGV 1343

Query: 845  PGLPGRDGVPGLVGVPGRPGVRG-------LKGLPGRNGEKGSQGF-GYPGEQGPPGPPG 896
            PG  G +G PGL+G PG PG+ G       +KG  G  G  G  G  G PG QGP G PG
Sbjct: 1344 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1403

Query: 897  PEGPPGI-SKEGPPG---------DPGLPGK------DGDHGKPGIQGQPGPPG 934
            P GPPG   + G PG         DPGLPG+      DG  G  G+QG PGPPG
Sbjct: 1404 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  395 bits (1014), Expect = e-109
 Identities = 246/553 (44%), Positives = 281/553 (50%), Gaps = 91/553 (16%)

Query: 436 DVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQ---PGQDGKPGYQGIAGTPGVPGS 492
           D G T   CI      G+ GP G PGLPG PG PG    PGQ G+ G  G  G  G+PG 
Sbjct: 476 DKGDTCFNCI----GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 493 PGIQGARGLPGYKGE-------PGRDGDKGDRGLPGFPGLHGMPGSKGE---MGAKGDKG 542
           PG  GA G PG KGE       PG  GDKG+ G PG PGL G+PG+ G+    G  G KG
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 543 SPGFYGKKGAKGEKGNAGFPGLP---GPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDG 599
            PG    KG +G  GN G PGLP   GP G PG  G  G +G  G +G AG+PG PG  G
Sbjct: 592 EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 600 TRGEPG----IPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP--GTPG 653
            +G+PG     PG PG  G  G+ G++G PG  G  G PG+PG+ GS G PG P  G PG
Sbjct: 651 PKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPG 710

Query: 654 SKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMG--------LPGIQGKKGDKGNQGE 705
             G KG PGI G PGA G  G  G  G PG PG+ G        LPG  G  G  G +G 
Sbjct: 711 PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA 770

Query: 706 KGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGP 765
            G +G +G  G  G PG+ G+ G  G KG+ G  G+PG  G  G  G       +G  GP
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-------IGVQGP 823

Query: 766 KGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHG 825
            G PG PGP G PGL G PG +           D     L V    G          + G
Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEK----------GDPGPPGLDVPGPPG----------ERG 863

Query: 826 SPGIPGPPGPIGPEGPRGLPGLPGRDGVPGL---------------VGVPGRPGVRGLK- 869
           SPGIPG PGPIGP G  GLPG  G  G PG                +G+PGR GV GLK 
Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923

Query: 870 --------GLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDH 921
                   GLPG  GEKGS+     GE G PGPPGP  P  +  +G  G+PGLPG  G  
Sbjct: 924 DDGLQGQPGLPGPTGEKGSK-----GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS 978

Query: 922 GKPGIQGQPGPPG 934
           G  G QG PG PG
Sbjct: 979 GPKGYQGLPGDPG 991



 Score =  392 bits (1006), Expect = e-108
 Identities = 253/597 (42%), Positives = 289/597 (48%), Gaps = 96/597 (16%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPG-------------YPG 470
           PGF GE        G    P I  PG PGL G  G PGLPG PG              PG
Sbjct: 399 PGFPGE----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 471 QPGQDGKPGYQGIAGTPGV-------------------PGSPGIQGARGLPGYKGEPGRD 511
            PG  G PG +G+ G  GV                   PG PG+ G  G PG  G PG+ 
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 512 GDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPG----FYGKKGAKGEKGNAGFPGLPGP 567
           G+KG  G  G  GL G+PG+ G  G  G KG PG    F G KG KGE G+ G PGLPG 
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 568 AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQ 627
            G PG+   DGL G PG KGE G     G+ G  G PG+PG PGN G MG  G  GPPG 
Sbjct: 575 PGTPGQ---DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGP 630

Query: 628 QGKKGA------PGMPGLMGSNGSPGQ----PGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
            G+KG       PG PG+ G  G PGQ    PG PG  G+ G  G  G+PG  GL G+PG
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPG 690

Query: 678 ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             G PG  G  G+PGI    G  G  G KG  G  G  G  G PG+ G++G  G  G  G
Sbjct: 691 LPGIPGSKGEPGIPGI----GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 738 EKGEPG--VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQ 795
            KGEPG  + G  G  G  G  G +GP G +G PG PGP G  GLDG PG +        
Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPK-------- 798

Query: 796 VCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPG 855
              DV     P  +    +      +   G PG PG PGPIG  G  G+PG  G  G PG
Sbjct: 799 --GDVGPNGQPGPMGPPGLPG----IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852

Query: 856 L-----------VGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGP 900
           L            G+PG PG  G  G PG  G+ G+ GF    G  G  GPPGPPGP G 
Sbjct: 853 LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 901 PGIS-------KEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDP 950
           PG S        +G  G PGLPG  G+ G  G  G PGPPG  DP+L  S   + +P
Sbjct: 913 PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969



 Score =  385 bits (990), Expect = e-107
 Identities = 252/647 (38%), Positives = 301/647 (46%), Gaps = 152/647 (23%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGN------------------ 465
           PG  G  L GP+ +   P P I PPG PGL GP G PGLPG                   
Sbjct: 179 PGIQG--LPGPTGI---PGP-IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQ 232

Query: 466 -----PGYPGQ-------------------PGQDGKPGYQGIAGTPGVPGSP-GIQGARG 500
                PG PGQ                   PG  G PG  GI G PG PG   G +G +G
Sbjct: 233 GLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG 292

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAK------- 553
            PG +G+PG+DG+ G  G+PG PG  G PG  G  G KG KG  G  G  G         
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTG 352

Query: 554 ---GEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
              GEKGN G PGLPG  GE          G PG +G  G PG PG     G PG PGFP
Sbjct: 353 ITIGEKGNIGLPGLPGEKGE---------RGFPGIQGPPGLPGPPGA-AVMGPPGPPGFP 402

Query: 611 GNRGLMGQKGEIG-----PPGQQGKKGAPGMPGLMG-------------SNGSPGQPGTP 652
           G RG  G +G  G     PPG  G+ GAPG+PG  G               G PG PG+P
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 653 GSKGSKGEPGIQGMPG----------ASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN 702
           G KG +GE G++G  G           SG  G+PG  G PG PG +G PG +G+KG  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 703 QGEKGIQGQKGENGRQGIPGQQGIQGH----HGAKGERGEKGEPGVRGAIGSKGESGVDG 758
            G KG+ G  G  G  G PG +G  G      G KG++GE G PG  G  G  G  G DG
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 759 LMGPAGPKGQPG------DPGPQGPPGLDGKPGR-------------EFSEQFIRQVCTD 799
           L G  GPKG+PG      + GP G PGL G PG                 E+ I+ V  +
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 800 VIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGL--- 856
             +  +P     G   +    ++Q G PG+PG PG  G  G  G PGLPG+ G+PG+   
Sbjct: 643 PGQPGIP-----GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 857 --------VGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEG 907
                   +G+PG PG +G  G+PG  G  G+ G  G  G  GPPG PGP+G PG +  G
Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPG 757

Query: 908 PPGDP---------------GLPGKDGDHGKPGIQGQPGPPGICDPS 939
           PPG P               G PG  G  G+ G+ G PGP G   P+
Sbjct: 758 PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804



 Score =  381 bits (978), Expect = e-105
 Identities = 234/516 (45%), Positives = 258/516 (50%), Gaps = 71/516 (13%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICP-----PGKPGLQGPKGDPGLPGNPGYPGQPGQDGK 477
            +PG  G  ++GP      P     P     PG PG  GPKG+PGLPG PG  G PG  G 
Sbjct: 971  LPGIPG--VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 478  PGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRG-----LPGFPG------LH 526
             G  G  G  GV G PG  G  G PG  G PG+ GDKGD G     LPG PG      L 
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 527  GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586
            G PG+ G  G+ GD G PG  G  GAKG+ G  GFPG PGP G  G  G  G  G PG  
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148

Query: 587  GEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS- 645
            G  G  G PGQ G  GE G PG  G  G  GQKGE G PG  G  G PG+PGL G  G  
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDG 1207

Query: 646  --PGQPGTPGSKGSKGEPGIQGMPGASGL--------------KGEPGATGSPGEPGYMG 689
              PG PG PG  G KGEPG  G PG  G               KG PG  G PG PG+ G
Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQG 1267

Query: 690  LPGIQGK---------KGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKG 740
            LPG +G          KG+KGN G+ G+ G  G  G QG PG QG  G  G  G +G+ G
Sbjct: 1268 LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPG 1327

Query: 741  EPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDV 800
             PGV G  G KG SGV G    AGP+G+PG  GP GPPGL G  G+         +  D 
Sbjct: 1328 LPGVPGFPGMKGPSGVPG---SAGPEGEPGLIGPPGPPGLPGPSGQSII------IKGDA 1378

Query: 801  IRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVP 860
                +P                Q G  G+PGP GP G  GP G PG PGR+G+PG  G  
Sbjct: 1379 GPPGIP---------------GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG 1423

Query: 861  GRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPG 896
            GR G  GL G PG  G  G    G  G QGPPGPPG
Sbjct: 1424 GRKGDPGLPGQPGTRGLDGPP--GPDGLQGPPGPPG 1457



 Score =  375 bits (964), Expect = e-104
 Identities = 249/633 (39%), Positives = 287/633 (45%), Gaps = 140/633 (22%)

Query: 423 IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGL------------------PG 464
           +PG  G    GP  +   P P   P G+ G +G +G+PG                   PG
Sbjct: 262 LPGDRGP--PGPPGIRGPPGP---PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 465 NPGYPGQPGQDGKPGYQGIAGTPGVP-------------GSPGIQGARGLPGYKGEPGRD 511
           +PGYPG+PG+DG+ G +G  G PG P             G  G  G  GLPG KGE G  
Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 512 GDKGDRGLPGFPGL-----HGMPGSKGEMGAKGDKGSPGFY--GKKGAKGEKGNAGFPGL 564
           G +G  GLPG PG       G PG  GE G KGD+G PG    G  G  G+ G  G PG 
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436

Query: 565 PGPA----------------GEPGRHGKDGLMGSPGFKGE-------------AGSPGAP 595
           PGPA                G PG  G  GL G  G KG+             +G PG P
Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP 496

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSP--------- 646
           G  G  G PG  GFPG +G  GQ G  GP G  G  GAPG PG  GS G P         
Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 647 -------GQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA------TGSPGEPGYMGLP-- 691
                  G PG PG  G  G PG  G+PG  G KGEPG        G PG PG  GLP  
Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616

Query: 692 ---------------GIQGKKGDKGNQGEKGIQGQKG-------ENGRQGIPGQQGIQGH 729
                          G +G +G  GN G+ GI G KG       + G+ G+PG  G  G 
Sbjct: 617 IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 676

Query: 730 HGAKGERGEKGEPGVRGAIGSKGESGVD--GLMGPAGPKGQPGDPGPQGPPGLDGKPGRE 787
            G  G+ G  G+PG+ G  GSKGE G+   GL GP GPKG PG PGP G PG  G+ G E
Sbjct: 677 VGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE 736

Query: 788 FSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGL 847
                             P      +           G PG+PG  G +GP+G RG PG 
Sbjct: 737 GPPG--------------PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782

Query: 848 PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGI---- 903
           PG  G  GL G+PG  G  G  G PG  G  G  G G  G  GPPG PGP G PG+    
Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 904 SKEGPPGDPGL--PGKDGDHGKPGIQGQPGPPG 934
            ++G PG PGL  PG  G+ G PGI G PGP G
Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875



 Score =  370 bits (949), Expect = e-102
 Identities = 247/646 (38%), Positives = 291/646 (45%), Gaps = 172/646 (26%)

Query: 439 STPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGA 498
           S  + C C  G  G +G +G PGL G+PG PG PG +G PG +G  G  G+PG PG +G 
Sbjct: 33  SPGSKCDCS-GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGI 91

Query: 499 RG---LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGE 555
           RG   LPG+ G PG  G  G  G PG  G+ G  G+KGE G  G  G PG  G  G  G 
Sbjct: 92  RGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 556 KGNAGFPG------LPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGF 609
            G  G PG      LPGP G PG  G  G+ G PG  G  G  G PG  G  G PG PG 
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL 211

Query: 610 PGNRGLM--------GQKGE------IGPPGQ-------------------QGKKGAPGM 636
           PG +G M        G+KGE       GPPGQ                    G +G PG 
Sbjct: 212 PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 637 PGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGK 696
           PG+ G  G PG  G  G KG +GEPG +G PG  G  G+PG  G PG+PGY G PG  G+
Sbjct: 272 PGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 697 K-------------------------GDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG 731
           K                         G+KGN G  G+ G+KGE G  GI G  G+ G  G
Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 732 A-----------KGERGEKGE--------PGVRGAIGSKGESGVDGLMGPAGPKGQPGD- 771
           A            GERG+KG+        PG  G  G  G  G+ G  GPAGP   P D 
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 772 ---PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCL------- 821
              PGP GPPG  G  G +  EQ ++    D                 C +C+       
Sbjct: 450 ICEPGPPGPPGSPGDKGLQ-GEQGVKGDKGD----------------TCFNCIGTGISGP 492

Query: 822 -SQHGSPGIPGPPGPI------------GPEGPRGLPGLP-------------------- 848
             Q G PG+PGPPG +            G  GP+GLPG+P                    
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 849 -----------GRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPP-- 895
                      G  G PGL G+PG PG  GL GLPG  GE G  G  + GE+GPPG P  
Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG--GITFKGERGPPGNPGL 610

Query: 896 -------GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                  GP GPPG    GP G+ G+ G  G+ G+PGI G  G PG
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656



 Score =  337 bits (864), Expect = 3e-92
 Identities = 199/450 (44%), Positives = 232/450 (51%), Gaps = 61/450 (13%)

Query: 448  PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
            PG  G++GP G  G+PG PG PG PGQ G  G  GI+   G+PG PG +G  GLPGY G 
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI-GLPGLPGPKGEPGLPGYPGN 1093

Query: 508  PGRDGDKGDRGLPGFPG---------LHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGN 558
            PG  G  GD GLPG PG         L G PG+ G  G KG  G PG  G  G  G  G 
Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153

Query: 559  AGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPG--------APGQDGTRGEPGIPGFP 610
             G PG PGP GE G+ G+DG+ G  G KGE G PG         PG  G +G+ G+PG P
Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213

Query: 611  GNRGLMGQKGEIGP---PGQQGKKGAPGMPG--LMGSNGSPGQPGTPGSKGSKGEPGIQG 665
            GN GL G KGE G    PG QG  G PG PG  L G  G+PG  G PG  G +G PG +G
Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEG 1273

Query: 666  ---MPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPG 722
               +PG  G+KGE G  G PG PG  GL G QG  G +GN G  G+ G KG+ G  G+PG
Sbjct: 1274 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG 1333

Query: 723  QQGIQGHHGAKGERGEKGEPGVRGAIGS-------------KGESGVDGLMGPAGPKGQP 769
              G++G  G  G  G +GEPG+ G  G              KG++G  G+ G  G KG P
Sbjct: 1334 FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP 1393

Query: 770  GDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI 829
            G  GPQG PG  G PG             D  R  LP    +G          + G PG+
Sbjct: 1394 GPQGPQGLPGPTGPPG-------------DPGRNGLPGFDGAG---------GRKGDPGL 1431

Query: 830  PGPPGPIGPEGPRGLPGLPGRDGVPGLVGV 859
            PG PG  G +GP G  GL G  G PG   V
Sbjct: 1432 PGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1461



 Score =  295 bits (756), Expect = 1e-79
 Identities = 195/484 (40%), Positives = 226/484 (46%), Gaps = 100/484 (20%)

Query: 496 QGARGLPGYKGEPGR----DGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKG 551
           Q A     Y   PG      G KG++G  GFPGL G PG             PGF G +G
Sbjct: 22  QPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGL------------PGFPGPEG 69

Query: 552 AKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611
             G +G  G  G+PGP G  G  G  GL   PGF G  G PG PG DG  G  GIPG  G
Sbjct: 70  PPGPRGQKGDDGIPGPPGPKGIRGPPGL---PGFPGTPGLPGMPGHDGAPGPQGIPGCNG 126

Query: 612 NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS---PGQPGTPGSKGSKGEPGIQGMPG 668
            +G  G  G  G PG QG  G PG+PG+ G  GS      PG  G+ G  G PGIQG+PG
Sbjct: 127 TKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPG 186

Query: 669 ASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQG 728
            +G+   PG  G PG PG MG PG  G  G KGN G    QG KGE G      +QG+QG
Sbjct: 187 PTGI---PGPIGPPGPPGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKG------EQGLQG 236

Query: 729 HHGAKGERGEKGEP-------GVRGAIGSKGESGVDGLMGPAGPKG-QPGDPGPQGPPGL 780
             G  G+  E+  P       G +G  G +G  G  G+ GP GP G + G+ G QG PG 
Sbjct: 237 PPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 781 DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG 840
            GKPG++                                   ++G PGIPG PG  G  G
Sbjct: 297 RGKPGKD----------------------------------GENGQPGIPGLPGDPGYPG 322

Query: 841 PRGLPGLPGRDGVPGLVGVPG----RPGV------RGLKGLPGRNGEKGSQGFGYPGEQG 890
             G  G  G+ G  G  G PG    RPG       +G  GLPG  GEKG +GF  PG QG
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF--PGIQG 380

Query: 891 PPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQ--------------GQPGPPGIC 936
           PPG PGP G   +   GPPG PG  G+ GD G PGI               G PGPPG  
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 937 DPSL 940
            P +
Sbjct: 441 GPHI 444



 Score =  236 bits (603), Expect = 6e-62
 Identities = 130/274 (47%), Positives = 150/274 (54%), Gaps = 18/274 (6%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG---IAGTPGVPGSPG--IQGARGL 501
            PPG PGL G KGD GLPG PG PG PG  G+PG+ G   + G PG PGSPG  ++G +G 
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN 1253

Query: 502  PGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGF 561
            PG +G PGR G +G   LPG  G  G+PG+ G  G KG+ G PG  G  G KG++G  G 
Sbjct: 1254 PGPQGPPGRPGFQG---LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1310

Query: 562  PGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQ--- 618
             G PG  G  G  G  GL G PGF G  G  G PG  G  GEPG+ G PG  GL G    
Sbjct: 1311 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ 1370

Query: 619  ----KGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKG 674
                KG+ GPPG  G+ G  G+PG  G  G PG  G PG  G  G PG  G   A G KG
Sbjct: 1371 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG---AGGRKG 1427

Query: 675  EPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
            +PG  G PG  G  G PG  G +G  G  G   +
Sbjct: 1428 DPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1461



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 17/36 (47%), Positives = 18/36 (50%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIA 484
            G PGL G  G  GL G PG  G  G  G PG   +A
Sbjct: 1427 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  409 bits (1052), Expect = e-114
 Identities = 239/545 (43%), Positives = 279/545 (51%), Gaps = 32/545 (5%)

Query: 414 QNNRETACEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPG 473
           +N  +     PG  GE  NG       P P + P G PG +G  G PG  G  G  G  G
Sbjct: 271 RNGEKGETGAPGLKGE--NGLPGENGAPGP-MGPRGAPGERGRPGLPGAAGARGNDGARG 327

Query: 474 QDGKPGYQGIAGTPGVPGSPGIQG---------ARGLPGYKGEPGRDGDKGDRGLPGFPG 524
            DG+PG  G  GT G PGSPG +G         + G PG +GEPG  G  G +G PG PG
Sbjct: 328 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG 387

Query: 525 LHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPG 584
           ++G PG KGEMG  G  G+PG  G +G  G  G  G PGL G AGEPG++G  G  G  G
Sbjct: 388 INGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRG 447

Query: 585 FKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNG 644
            +GEAG PG PG  G  G+ G PG PG  GL G  GE G PG +G  G  G+PG  G  G
Sbjct: 448 ERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507

Query: 645 SPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQG 704
             G PG  G +G+ GEPG  G+PG  G++G P   GSPG PG  G PG  G +G+ G  G
Sbjct: 508 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP---GSPGGPGSDGKPGPPGSQGESGRPG 564

Query: 705 EKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAG 764
             G  G +G+ G  G PG +G  G  G  GERG  G PG +G  G  GE+G  G  GP G
Sbjct: 565 PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG 624

Query: 765 PKGQPGDPGPQGPPGLDGKPGR-----EFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDH 819
           P G  GD GP GP GL G PG      E  +        D      P             
Sbjct: 625 PGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERG 684

Query: 820 CLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKG 879
                G+PG+ G  GP GPEG +G  G PG  G  G  G+ G PG RG  G PG  G+KG
Sbjct: 685 PPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKG 744

Query: 880 SQG----FGYPGEQGPPGPPGPEGPPGISKEGPPGD------PGLPGKDGDHGKPGIQGQ 929
             G     G PG+ GP GP GP GPPG    G PGD      PGLPG  G  G PG +G+
Sbjct: 745 EPGGPGADGVPGKDGPRGPTGPIGPPG--PAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802

Query: 930 PGPPG 934
            GPPG
Sbjct: 803 TGPPG 807



 Score =  396 bits (1017), Expect = e-110
 Identities = 229/516 (44%), Positives = 264/516 (51%), Gaps = 61/516 (11%)

Query: 447 PPGKPGLQGPKGDPGLPGNPGY------PGQPGQDGKPGYQGIAGTPGVPGSPGIQGARG 500
           PPG PG  G  G PG PG+PGY      PGQ G  G PG  G  G  G  G  G  G  G
Sbjct: 178 PPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPG 237

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAG 560
            PG +G PG  G KG  G+PGFPG+ G  G  G  G KG+ G+PG  G+ G  GE    G
Sbjct: 238 RPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN---G 294

Query: 561 FPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKG 620
            PG  GP G PG  G+ GL G+ G +G  G+ G+ GQ G  G PG  GFPG+ G  G+ G
Sbjct: 295 APGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVG 354

Query: 621 EIGPPGQQ---GKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
             G PG     G++G PG  G  G+ G PG PG  GS G KGE G  G+PGA GL    G
Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLM---G 411

Query: 678 ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
           A G PG  G  G PG++G  G+ G  G KG  G +GE G  GIP   G+ G  G  G+ G
Sbjct: 412 ARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIP---GVPGAKGEDGKDG 468

Query: 738 EKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGD---------PGPQGPPGLDGKPGREF 788
             GEPG  G  G+ GE G  G  GPAGP G PG+         PGP GP G  G+PGR+ 
Sbjct: 469 SPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD- 527

Query: 789 SEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLP 848
                  V        +P                  G PG  G PGP G +G  G PG P
Sbjct: 528 ------GVPGGPGMRGMP---------------GSPGGPGSDGKPGPPGSQGESGRPGPP 566

Query: 849 GRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPP---------GPPGPEG 899
           G  G  G  GV G PG +G  G PG+NGE+G  G G PG QGPP         GPPGP G
Sbjct: 567 GPSGPRGQPGVMGFPGPKGNDGAPGKNGERG--GPGGPGPQGPPGKNGETGPQGPPGPTG 624

Query: 900 PPGISKE-GPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           P G   + GPPG  GL G  G  G PG  G+PG PG
Sbjct: 625 PGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG 660



 Score =  396 bits (1017), Expect = e-110
 Identities = 243/604 (40%), Positives = 283/604 (46%), Gaps = 121/604 (20%)

Query: 424  PGFNGECLNGPSDV-------GSTPAPCICPP----GKPGLQGPKGDPGLPGNPGYPGQP 472
            PGF G    GP+ +       G   AP    P    G+PG  G  G PG+ G PG PG P
Sbjct: 488  PGFRGPA--GPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP 545

Query: 473  GQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGD------KGDRGLPGFPGLH 526
            G DGKPG  G  G  G PG PG  G RG PG  G PG  G+       G+RG PG PG  
Sbjct: 546  GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605

Query: 527  GMPGSKGEMGAKG---------DKGS------------------PGFYGKKGAKGEKGNA 559
            G PG  GE G +G         DKG                   PG  GK G  G KG+A
Sbjct: 606  GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDA 665

Query: 560  GFPGLPG---PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGF---PGNR 613
            G PG PG    AG PG  G  GL G+PG +G AG PG  G  G  G PG PG    PG +
Sbjct: 666  GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ 725

Query: 614  GLMGQKGEIGPPGQQGKKGAPGMPGL---------MGSNGSPGQPGTPGSKGSKGEPGIQ 664
            G+ G++G +G PG +G KG PG PG           G  G  G PG  G  G KGE G  
Sbjct: 726  GMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAP 785

Query: 665  GMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQ 724
            G+PG +G +G PG  G  G PG  G PG  G+ G+ G +GE+G  G+KGE G  G+ G  
Sbjct: 786  GLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP 845

Query: 725  GIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKP 784
            G  G  G  G +G KGE G  G  G+ G  G  GL GP G  G PG PGP G PG DG P
Sbjct: 846  GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP 905

Query: 785  GREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGL 844
            G   +                                   GSPG+ GP G  G  G +G 
Sbjct: 906  GPAGN-------------------------------TGAPGSPGVSGPKGDAGQPGEKGS 934

Query: 845  PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPP---------GP 894
            PG  G  G PG +G+ G  G RGL G PG  G +GS G  G  GE G P         GP
Sbjct: 935  PGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP 994

Query: 895  PGPEGPPGIS-------KEGPPGDPGLPGKD------------GDHGKPGIQGQPGPPGI 935
            PGP+G PG++       ++G PG  GLPG+D            G  G PG  G PGPPG 
Sbjct: 995  PGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP 1054

Query: 936  CDPS 939
              P+
Sbjct: 1055 VGPA 1058



 Score =  393 bits (1010), Expect = e-109
 Identities = 225/516 (43%), Positives = 256/516 (49%), Gaps = 52/516 (10%)

Query: 448 PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
           PG  G  G  G PG PG  G PG  G+ G PG++G AG  G+PG  G  G RG PG  G 
Sbjct: 458 PGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGP 517

Query: 508 PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP 567
            G  G+ G  G+PG PG+ GMPGS G  G+ G  G PG  G+ G  G  G +G  G PG 
Sbjct: 518 RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGV 577

Query: 568 AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQ 627
            G PG  G DG  G  G +G  G PG  G  G  GE G  G PG  G  G KG+ GPPG 
Sbjct: 578 MGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP 637

Query: 628 QGKKGAPGMPGLMGSNGSPGQ---------PGTPGSKGSKGEPGIQGMPGASGL------ 672
           QG +G PG  G  G NG PG+         PG PG KG  G PG +G PG +G       
Sbjct: 638 QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697

Query: 673 ------KGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGI 726
                 +G  GA G PG PG  G PG+QG  G++G  G  G +G KGE G    PG  G+
Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG---PGADGV 754

Query: 727 QGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGR 786
            G  G +G  G  G PG  G  G KGE G  GL G AGP+G PG+ G  GPPG  G PG 
Sbjct: 755 PGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGA 814

Query: 787 EFSEQFIRQVCTDVIRAQLPVLLQSGR-----IRNCDHCLSQHGSPGIPGPPGPIGPEGP 841
                                  Q+G       R       + G PG+ GPPG  GP GP
Sbjct: 815 PG---------------------QNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP 853

Query: 842 RGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGP 900
            G  G+ G  G PG  G  G PG RGL G PG NG  G  G  G PG+ GPPGP G  G 
Sbjct: 854 PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA 913

Query: 901 PGI-SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
           PG     GP GD G PG+ G  G  G  G PGP GI
Sbjct: 914 PGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949



 Score =  390 bits (1003), Expect = e-108
 Identities = 221/509 (43%), Positives = 262/509 (51%), Gaps = 54/509 (10%)

Query: 447 PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
           PPG PG  GP G  G  G  G PG+PG+ G PG  GI G  G+PG PG++G RG  G  G
Sbjct: 214 PPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNG 273

Query: 507 EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
           E G  G  G +G  G PG +G PG  G  GA G++G PG  G  GA+G  G  G  G PG
Sbjct: 274 EKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPG 333

Query: 567 PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPG 626
           P G PG  G  G  G+ G  G AGSPG+ G  G RGEPG  G  G +G  G  G  G PG
Sbjct: 334 PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPG 393

Query: 627 QQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPG 686
            +G+ G  G+PG  G  G+ G PG  G+ G+ G  G  G PG +G KGEPG  G  GE G
Sbjct: 394 GKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAG 453

Query: 687 YMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGER---GEKGEPG 743
             G+PG +G+ G  G+ GE G  G  G  G +G PG +G  G +G  GE+   GE+G PG
Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG 513

Query: 744 VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRA 803
             G  G+ GE G DG+ G  G +G PG P   G PG DGKPG   S+             
Sbjct: 514 PAGPRGAAGEPGRDGVPGGPGMRGMPGSP---GGPGSDGKPGPPGSQ------------- 557

Query: 804 QLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRP 863
                              + G PG PGP GP G  G  G PG  G DG PG  G  G P
Sbjct: 558 ------------------GESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 599

Query: 864 GVRGLKGLPGRNGEKGSQG-------FGYPGEQGPPGP------PGPEGPPGIS----KE 906
           G  G +G PG+NGE G QG        G  G+ GPPGP      PG  GPPG +    + 
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEP 659

Query: 907 GPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
           GP GD G PG  G  G  G  G+ GPPG+
Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGL 688



 Score =  390 bits (1002), Expect = e-108
 Identities = 248/602 (41%), Positives = 286/602 (47%), Gaps = 112/602 (18%)

Query: 424  PGFNGEC----LNGPSDVGSTPAPCICPPGKPGLQG------PKGDPGLPGNPGYPGQPG 473
            PG NGE       GP+  G        PPG  GLQG      P G+ G PG PG  G  G
Sbjct: 608  PGKNGETGPQGPPGPTGPGGDKGDT-GPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666

Query: 474  QDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPG------FPGLHG 527
              G PG +G AG PG  G PG+ GA GL G  G PG +G KG  G PG       PGL G
Sbjct: 667  APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQG 726

Query: 528  MPGSKGEMGA---KGDKGSPGFYGKKGAKGE---KGNAGFPGLPGPAGEPGRHGKDGLMG 581
            MPG +G +G+   KGDKG PG  G  G  G+   +G  G  G PGPAG+PG  G+ G  G
Sbjct: 727  MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786

Query: 582  SPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM---PG 638
             PG  G  GSPG  G+ G  G  G PG PG  G  G KGE G PG++G+ G PG+   PG
Sbjct: 787  LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG 846

Query: 639  LMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPG------ 692
              G  G PG  G  G +GS G PG  G PGA GL G PG+ G+PG PG  G PG      
Sbjct: 847  GSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPG 906

Query: 693  ------------IQGKKGDKGNQGEKGIQGQKGENGRQG------IPGQQGIQGHHGAKG 734
                        + G KGD G  GEKG  G +G  G  G      I G +G+ G  G  G
Sbjct: 907  PAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPG 966

Query: 735  ERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG------DPGPQGPPGLDGKPGREF 788
             RG  G  GV+G  G  G +G+ G  GP GP+G PG      +PG  G PG DG PGR+ 
Sbjct: 967  PRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDG 1026

Query: 789  SEQFIRQVCTDVIRAQLPVLLQSGR-IRNCDHCLSQHGSPGIPGPPGPIGPEG------- 840
            S                      G+  R  +      G+PG PGPPGP+GP G       
Sbjct: 1027 SP--------------------GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE 1066

Query: 841  -----PRGLPGLPGRDGVPGL---------VGVPGRPGVRGLKGLPGRNGEKGSQG---- 882
                 P G PG  G  G PG           G  G  G++G +G PG  G  GS G    
Sbjct: 1067 SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQ 1126

Query: 883  ---FGYPGEQGPPGPPGPEGPPGISKE-------GPPGDPGLPGKDGDHGKPGIQGQPGP 932
                G PG  GP GP GP GPPG           GPPG  G  G+ G  G PG  GQPGP
Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGP 1186

Query: 933  PG 934
            PG
Sbjct: 1187 PG 1188



 Score =  379 bits (973), Expect = e-105
 Identities = 229/555 (41%), Positives = 263/555 (47%), Gaps = 67/555 (12%)

Query: 429 ECLNGPSDVGSTPAPCICPPGKP-------GLQGPKGDPGLPGNPGYPGQPGQDGKPGYQ 481
           +C N     G   A C  PP  P       G QGPKGDPG PG PG  G PG  G+PG  
Sbjct: 73  DCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSP 132

Query: 482 GIAGTPGV----PGSP-------------------GIQGARGLPGYKGEPGRDGDKGDRG 518
           G  G PG+    P  P                   G+ G  G  G  G PG  G  G  G
Sbjct: 133 GSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPG 192

Query: 519 LPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDG 578
            PG PG  G PG  G+ G  G  G PG  G  G  G+ G +G PG PG  G PG  G  G
Sbjct: 193 SPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKG 252

Query: 579 LMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGP------PGQQGKKG 632
             G PGF G  G  G  G++G +GE G PG  G  GL G+ G  GP      PG++G+ G
Sbjct: 253 PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPG 312

Query: 633 APGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPG 692
            PG  G  G++G+ G  G PG  G  G  G  G PGA G  G  G+ GS G PG  G PG
Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372

Query: 693 IQGKKGDKGNQGEKGIQGQ---KGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIG 749
            QG  G +G  G  GI G    KGE G  GIPG  G+ G  G  G  G  G PG+RG  G
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432

Query: 750 SKGESGVDGLMGPAGPKGQ---PGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLP 806
             G++G  G  GP G +G+   PG PG +G  G DG PG   +                 
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANG--------------- 477

Query: 807 VLLQSGRIRNCDHCLSQHGSPGIPGPPGPI------GPEGPRGLPGLPGRDGVPGLVGVP 860
            L  +   R         G  GIPG  GP       GP GPRG  G PGRDGVPG  G+ 
Sbjct: 478 -LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMR 536

Query: 861 GRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGI-SKEGPPGDPGLPGKDG 919
           G PG  G  G  G+ G  GSQ  G  G  GPPGP GP G PG+    GP G+ G PGK+G
Sbjct: 537 GMPGSPGGPGSDGKPGPPGSQ--GESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594

Query: 920 DHGKPGIQGQPGPPG 934
           + G PG  G  GPPG
Sbjct: 595 ERGGPGGPGPQGPPG 609



 Score =  374 bits (959), Expect = e-103
 Identities = 232/522 (44%), Positives = 254/522 (48%), Gaps = 27/522 (5%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PG NGE   GP   G        PPGK G  GP+G PG P  PG  G  G  G PG QG+
Sbjct: 590  PGKNGE-RGGPGGPGPQG-----PPGKNGETGPQGPPG-PTGPG--GDKGDTGPPGPQGL 640

Query: 484  AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
             G PG  G PG  G  G PG KG+ G  G  G +G  G PG  G PG  G  G +G  G 
Sbjct: 641  QGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP 700

Query: 544  PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGA---PGQDGT 600
            PG  G KGA G  G  G  G PG  G PG  G  G  G  G KGE G PGA   PG+DG 
Sbjct: 701  PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGP 760

Query: 601  RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660
            RG  G  G PG  G  G KGE G PG  G  G  G PG  G  G PG  G PG+ G  GE
Sbjct: 761  RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE 820

Query: 661  PGIQGMPGASGLKGE---PGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
            PG +G  GA G KGE   PG  G PG  G  G PG QG KG++G+ G  G  G  G  G 
Sbjct: 821  PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGL 880

Query: 718  QGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGP 777
             G PG  G  G  G  G  G+ G PG  G  G+ G  GV G  G AG  G+ G PG QGP
Sbjct: 881  PGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGP 940

Query: 778  PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIG 837
            PG  G  G       I  +      A  P +              + G PG  G  G  G
Sbjct: 941  PGAPGPLG-------IAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERG 993

Query: 838  PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGPPGPPG 896
            P GP+GLPGL G  G PG  G PG  G+ G  G PG  G++G  G  G PG  G PGPPG
Sbjct: 994  PPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPG 1053

Query: 897  PEGPPGIS----KEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            P GP G S    + GP G  G PG  G  G PG QG  G  G
Sbjct: 1054 PVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKG 1095



 Score =  360 bits (923), Expect = 5e-99
 Identities = 220/516 (42%), Positives = 253/516 (49%), Gaps = 82/516 (15%)

Query: 433  GPSDVGSTPAPCICPPGKPGL--QGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVP 490
            GP     TP     P  + GL   GPKGD G PG PG  G PG+DG  G  G  G PG  
Sbjct: 714  GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA 773

Query: 491  GSPGIQG---ARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFY 547
            G PG +G   A GLPG  G  G  G++G+ G PG  G  G PG  GE G KG++G+PG  
Sbjct: 774  GQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPG-- 831

Query: 548  GKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIP 607
             +KG  G  G AG PG  GPAG PG  G  G  GSPG  G AG PGA G  G  G  G P
Sbjct: 832  -EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890

Query: 608  GFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMP 667
            G PG  G     G+ GPPG  G  GAPG PG+ G  G  GQPG  GS G++G PG  G  
Sbjct: 891  GPPGPSG---SPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 668  GASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQ 727
            G +G+ G  G  G PG PG  G PG QG KG+ G  G  G+ G++G  G QG+PG  G  
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 728  GHHG------------------AKGERGEKGEPGVRGA---------IGSKGESGVDGLM 760
            G  G                   KG+RGE G PG  GA         +G  G+SG  G  
Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067

Query: 761  GPAGPKGQPGD------PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
            GPAGP G PG       PGPQGP G  G+ G                         +  I
Sbjct: 1068 GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGER----------------------GAAGI 1105

Query: 815  RNCDHCLSQHGSPGIPGP---------PGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGV 865
            +         G+PG PGP         PGP GP GP G  G PG+DG  G  G  G PG 
Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGP 1165

Query: 866  RGLKGLPGRNGEKGSQGF-GYPGEQGPPGPPGPEGP 900
            RG        GE+GS+G  G+PG+ GPPGPPG  GP
Sbjct: 1166 RG------NRGERGSEGSPGHPGQPGPPGPPGAPGP 1195



 Score =  305 bits (782), Expect = 1e-82
 Identities = 202/523 (38%), Positives = 240/523 (45%), Gaps = 109/523 (20%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICP--------PGKPGLQGPKGDPGL------PGNPGY 468
            +PG +G    GP+     P P   P        PG PG+ GP+G PG       PG  G+
Sbjct: 754  VPGKDGP--RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811

Query: 469  PGQPGQDGKPGYQGIAGTPGVPGS---PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGL 525
            PG PGQ+G+PG +G  G PG  G    PG+ G  G  G  G PG  G KG+RG PG PG 
Sbjct: 812  PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGA 871

Query: 526  HGMPGSKGEMGAKGDKGSPG------FYGKKGAKGEKGNAGFPGLPG------PAGEPGR 573
             G PG++G  G  G  G+PG        GK G  G  GN G PG PG       AG+PG 
Sbjct: 872  AGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGE 931

Query: 574  HGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQG---K 630
             G  G  G PG  G  G  G  G  G  G PG+PG  G+ G  G KGE G PG  G   +
Sbjct: 932  KGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE 991

Query: 631  KGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGL 690
            +G PG  GL G  G+ G+PG  G+ GS G PG  G PG  G +GE G+ G+PG PG+ G 
Sbjct: 992  RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051

Query: 691  PGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRG---- 746
            PG  G  G  G++GE G  G  G  G  G  G  G QG  G KGE GE+G  G++G    
Sbjct: 1052 PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGF 1111

Query: 747  -----------------AIGSKGESGVDGLMGPAGPKGQPGD---PGPQGPPGLDGKPGR 786
                             AIGS G +G  G +GP+GP G+ G    PGP GPPG  G  G 
Sbjct: 1112 PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE 1171

Query: 787  EFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPG 846
              SE                                  GSPG PG PGP GP      PG
Sbjct: 1172 RGSE----------------------------------GSPGHPGQPGPPGP------PG 1191

Query: 847  LPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQ 889
             PG    P   GV       G   + G  GEK      Y G++
Sbjct: 1192 APG----PCCGGV-------GAAAIAGIGGEKAGGFAPYYGDE 1223



 Score =  291 bits (746), Expect = 2e-78
 Identities = 184/454 (40%), Positives = 208/454 (45%), Gaps = 84/454 (18%)

Query: 509 GRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGF-----------------YGKKG 551
           G  G KGD G PG PG +G PG  G+ G+ G  G PG                  Y  K 
Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162

Query: 552 AKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611
                G AG+PG  GP G PG  G  G  GSPG  G  G PG PGQ G  G PG P    
Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP---- 218

Query: 612 NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASG 671
                   G IGP G  GK G  G PG  G  G PG PG  G  G  G PG++G  G  G
Sbjct: 219 --------GAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDG 270

Query: 672 LKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG 731
             GE G TG+PG  G  GLPG      + G  G  G +G  GE GR G+PG  G +G+ G
Sbjct: 271 RNGEKGETGAPGLKGENGLPG------ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG 324

Query: 732 AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQ 791
           A+G  G+ G PG  G  G  G  G  G +GPAG  G  G PG +G PG  G  G      
Sbjct: 325 ARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG------ 378

Query: 792 FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRD 851
                      AQ P                  G PGI G PG  G  GP G+PG PG  
Sbjct: 379 -----------AQGPP-----------------GPPGINGSPGGKGEMGPAGIPGAPGLM 410

Query: 852 GV---PGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEG 907
           G    PG  G  G PG+RG  G PG+NG KG  G  G  GE G PG PG +G     ++G
Sbjct: 411 GARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG-----EDG 465

Query: 908 PPGDP------GLPGKDGDHGKPGIQGQPGPPGI 935
             G P      GLPG  G+ G PG +G  GP GI
Sbjct: 466 KDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499



 Score =  207 bits (528), Expect = 3e-53
 Identities = 133/338 (39%), Positives = 143/338 (42%), Gaps = 63/338 (18%)

Query: 626 GQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGI-QGMP----------------- 667
           G QG KG PG PG+ G NG PG PG PGS GS G PGI +  P                 
Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162

Query: 668 --GASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQG 725
                GL G PG  G PG PG  G  G  G  G  G QG  G  GQ G +G  G PG  G
Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG 222

Query: 726 IQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPG 785
             G  G  GE G  G PG RG  G  G  G  G+ G  G KG  G  G  G  G  G PG
Sbjct: 223 PSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPG 282

Query: 786 REFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLP 845
            +                                     G  G+PG  G  GP GPRG P
Sbjct: 283 LK-------------------------------------GENGLPGENGAPGPMGPRGAP 305

Query: 846 GLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGPP 901
           G  GR G+PG  G  G  G RG  G PG  G  G+ GF    G  GE GP G PG  G P
Sbjct: 306 GERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAP 365

Query: 902 GISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
           G  + G PG  G  G  G  G PGI G PG  G   P+
Sbjct: 366 G--QRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401



 Score =  100 bits (248), Expect = 8e-21
 Identities = 55/129 (42%), Positives = 64/129 (49%), Gaps = 22/129 (17%)

Query: 830 PGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF------ 883
           P   GP GP+G  G PG+PGR+G PG+ G PG PG  G  G+   +   G Q +      
Sbjct: 99  PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGI-CESCPTGPQNYSPQYDS 157

Query: 884 -------------GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQP 930
                        GYPG  GPPGPPGP G  G    G PG PG  G  G+ G+ G  G P
Sbjct: 158 YDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG--HPGSPGSPGYQGPPGEPGQAGPSGPP 215

Query: 931 GPPGICDPS 939
           GPPG   PS
Sbjct: 216 GPPGAIGPS 224


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  409 bits (1051), Expect = e-114
 Identities = 247/546 (45%), Positives = 278/546 (50%), Gaps = 51/546 (9%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGN--PGYPGQPGQDGKPGYQ 481
            PG  G  + GP      P P I  PG  G+ G KGDPG PG   PG PG+ G  G PG  
Sbjct: 813  PGLPGIGVQGPPGPPGIPGP-IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAP 871

Query: 482  GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDK 541
            G  G PG PG PG  GA G PG KGE G  G  G  G  G PG  G+PG KG+ G +G  
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931

Query: 542  GSPGFYGKKGAKGE-----------------KGNAGFPGLPGPAGEPGRHGKDGLMGSPG 584
            G PG  G+KG+KGE                 KG  G PGLPG  G  G  G  GL G PG
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPG 991

Query: 585  FKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNG 644
              G +G PG PG  G +G PG+PG PG  G  G KG IG  G  G +G  G PG  G  G
Sbjct: 992  QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 645  SPGQPGTPGSKGSKGEPGIQ--GMPGASGLKGEPGATGSPGEPGYM------GLPGIQGK 696
             PG PG PG KG KG+PGI   G+PG  G KGEPG  G PG PG        GLPG+ G 
Sbjct: 1052 QPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111

Query: 697  KGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGV 756
             G KG  G  G  G  G  G +GI G  G  G  G  G  G  G PG  G  G KG+ G 
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 757  DGLMGPAGPKGQPGDP--GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
            DG+ GPAG KG+PG P  G  GPPGL G  G++                 LP +  +  +
Sbjct: 1172 DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD-------------GGLPGIPGNPGL 1218

Query: 815  RNCDHCLSQHGSPGIPGPPGPIGP-----EGPRGLPGLPGRDGVPGLVGVPGRPGVRGLK 869
                     HG PG+ GPPGP G      EGP+G PG  G  G PG  G  G PG  G  
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPP 1278

Query: 870  GLPGRNGEKGSQGF-GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQG 928
            GLPG  G KG +G  G PG  G PG  G +GPPG+  +G PG PGL G  GD G PG+ G
Sbjct: 1279 GLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL--QGNPGRPGLNGMKGDPGLPGVPG 1336

Query: 929  QPGPPG 934
             PG  G
Sbjct: 1337 FPGMKG 1342



 Score =  407 bits (1045), Expect = e-113
 Identities = 252/578 (43%), Positives = 292/578 (50%), Gaps = 93/578 (16%)

Query: 434  PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQ---DGKPGYQGIAGTPGVP 490
            P   GS   P I   G PG  GPKG PG+PG PG PG PG+   +G PG  G  G  G P
Sbjct: 692  PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP 751

Query: 491  G--SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFP---GLHGMPGSKGEMGAKGDKGSPG 545
            G   PG  G  GLPG+KG  G  GD+G  G PG P   GL G+PG KG++G  G  G  G
Sbjct: 752  GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811

Query: 546  FYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDG-----------LMGSPGFKGEAGSPGA 594
              G  G  G +G  G PG+PGP G+PG HG  G           + G PG +G  G PGA
Sbjct: 812  PPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870

Query: 595  PGQDGTRGEPGIP------GFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQ 648
            PG  G  G PG+P      GFPG +G MG  G  GPPG  G  G  G+PGL G +G  GQ
Sbjct: 871  PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQ 930

Query: 649  PGTP--------------------------GSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
            PG P                          GSKG KGEPG+ G+PG SG KG  G  G P
Sbjct: 931  PGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP 990

Query: 683  GEPGYMGLPGIQGKKGDKGNQGEK------GIQGQKGENGRQGIPGQQGIQGHHGAKGER 736
            G+PG  G PG+ G  G KGN G        G  G KG  G  G PG QG++G  G  G  
Sbjct: 991  GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP 1050

Query: 737  GEKGEPGVRGAIGSKGESGVD--GLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIR 794
            G+ G PG+ G  G KG+ G+   GL G  GPKG+PG PG  G PG+ G  G         
Sbjct: 1051 GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG--------- 1101

Query: 795  QVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVP 854
                      LP L  +   +         G PG PGPPGP G  GP G PGLPG  G  
Sbjct: 1102 -------DPGLPGLPGTPGAKGQP---GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 855  GLVGVPGRPGVRGLKGLPGRN---------GEKGSQGFGYPGEQGPPGPPGPEGPPGISK 905
            G  G PG+PG  G KG PG++         GE G  GFG PG  G PG  G +G  G+  
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL-- 1209

Query: 906  EGPPGDPGLPGKDGD---HGKPGIQGQPGPPGICDPSL 940
             G PG+PGLPG  G+   HG PG+QG PGPPG   P+L
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247



 Score =  405 bits (1041), Expect = e-113
 Identities = 254/566 (44%), Positives = 289/566 (51%), Gaps = 63/566 (11%)

Query: 422  EIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQ 481
            ++PG  GE   G   +   P P I PPG PGL G  G  G PG  G  G  G  G PG  
Sbjct: 854  DVPGPPGE--RGSPGIPGAPGP-IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 482  GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLH--GMPGSKGEMGAKG 539
            GI G  GVPG  G  G +G PG  G  G  G KG+ GLPG PG     + GSKGE G  G
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 540  DKGSPGFYGKKGAKGEKGNAGFPGL---------PGPAGEPGRHGKDGLMGSPGFKGEAG 590
              G PG  G KG +G  G+ G PGL         PGP G PG  G+ GL+G PG KG  G
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 591  SPGAPGQDGTRGEPG---IPGFPGNRGLMGQKGE--------IGPPGQQGKKGAPGMPG- 638
              G PG  G  G PG   +PG PG+ GL GQKG+        IG PG  G KG PG+PG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 639  -----LMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA------SGLKGEPGATGSPGEPG- 686
                 + GS G PG PG PG+ G+KG+PG+ G PG        G+ G PG  G PGEPG 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150

Query: 687  -----YMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI--PGQQGIQGHHGAKGERGEK 739
                 + G PG  G+KG  G  G  G  GQKGE G+ G   PG  G+ G  G KG+ G  
Sbjct: 1151 VGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 740  GEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGP-----QGPPGLDGKPGREFSEQFIR 794
            G PG  G  G KGE G  G  G  GP G PG PGP     +G PG  G PGR     F  
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQG 1270

Query: 795  QVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVP 854
                +      P L  +G I+         G PG+PG PG  G +GP GL G PGR G+ 
Sbjct: 1271 LPGPE----GPPGLPGNGGIKGEK---GNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1323

Query: 855  GLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGIS-----KEGP 908
            G+ G PG PGV G  G+ G +G  GS G  G PG  GPPGPPG  GP G S       GP
Sbjct: 1324 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP 1383

Query: 909  PGDPGLPGKDGDHGKPGIQGQPGPPG 934
            PG PG PG  G  G  G QG PGP G
Sbjct: 1384 PGIPGQPGLKGLPGPQGPQGLPGPTG 1409



 Score =  405 bits (1041), Expect = e-113
 Identities = 242/537 (45%), Positives = 274/537 (51%), Gaps = 98/537 (18%)

Query: 448  PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
            PG PG+ GPKG  GLPG+PG PG  GQ G PG  G  G PG+PG PG+ G  GL G  G+
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031

Query: 508  PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP 567
             G  G +G  G PG  G+ G PGS G  G KGDKG PG            + G PGLPGP
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI----------SSIGLPGLPGP 1081

Query: 568  AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQ 627
             GEPG  G  G  G  G  G+ G PG PG  G +G+PG+PGFPG  G  G KG  GPPG 
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141

Query: 628  QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGY 687
             G    PG PG +G  G PGQPG PG KG   +PG  G+PG +G KGEPG  G  G PG 
Sbjct: 1142 PG---LPGEPGPVGGGGHPGQPGPPGEKG---KPGQDGIPGPAGQKGEPGQPGF-GNPGP 1194

Query: 688  MGLPGIQGKKGD---KGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGE--RGEKGEP 742
             GLPG+ G+KGD    G  G  G+ G KGE G  G PG QG  G  G+ G    G KG P
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP 1254

Query: 743  GVRGAIGSKGESGVDGLMGPAGP------------KGQPGDPG---------PQGPPGLD 781
            G +G  G  G +G  GL GP GP            KG PG PG          QGPPGL 
Sbjct: 1255 GPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ 1314

Query: 782  GKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP 841
            G PGR                                      G PG+PG PG  G +GP
Sbjct: 1315 GNPGRPGLN-------------------------------GMKGDPGLPGVPGFPGMKGP 1343

Query: 842  RGLPGLPGRDGVPGLVGVPGRPGVRG-------LKGLPGRNGEKGSQGF-GYPGEQGPPG 893
             G+PG  G +G PGL+G PG PG+ G       +KG  G  G  G  G  G PG QGP G
Sbjct: 1344 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1403

Query: 894  PPGPEGPPGI-SKEGPPG---------DPGLPGK------DGDHGKPGIQGQPGPPG 934
             PGP GPPG   + G PG         DPGLPG+      DG  G  G+QG PGPPG
Sbjct: 1404 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  402 bits (1034), Expect = e-112
 Identities = 254/574 (44%), Positives = 291/574 (50%), Gaps = 99/574 (17%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPG----------------YQGIAGTPGVPGS 492
            G+ G  GPKG PG+PG PG PG PG  G+PG                  G  G PG+PG+
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 493  PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGA 552
            PG  G  GLPG KGEPG    KG+RG PG PGL G+PG+ G MG  G  G PG  G+KG 
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGI 636

Query: 553  KGEKGNAGFPGLPGPAGEPG----RHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPG 608
            +G  GN G PG+PGP G+PG    + GK GL G+PG  G+ G PG PG  G  G PGIPG
Sbjct: 637  QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG 696

Query: 609  FPGNR-----GLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGS------ 657
              G       GL G  G  G PG  G  GAPG PG +G  G PG PG PG KG       
Sbjct: 697  SKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP 756

Query: 658  --KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQ---- 711
               G PG+ G  GA G KG+ G  G PG PG  GL G+ G KGD G  G+ G  G     
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 712  ----KGENGRQGIPGQQGIQGHHGAKGERGEKGEPG--VRGAIGSKGESGVDGLMGPAGP 765
                +G  G  GIPG  G  G HG  GE+G+ G PG  V G  G +G  G+ G  GP GP
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 766  KGQPGDP------------------GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPV 807
             G PG P                  GP GPPG  G PGR            D ++ Q  +
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD---DGLQGQPGL 933

Query: 808  LLQSGRIRNCDHCLSQHGSPGIPGPPGP-----IGPEGPRGLPGLPGRDGV------PGL 856
               +G            G PG+PGPPGP     +G +G +G PGLPG  GV       GL
Sbjct: 934  PGPTGE-------KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986

Query: 857  VGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGP------------PGPPGPEGPPGI 903
             G PG+PG+ G  GLPG  G KG+ G  G PG  GP            PGP G EGPPG 
Sbjct: 987  PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046

Query: 904  S-KEGPPGDPGLPGKDGDHGKPGIQ--GQPGPPG 934
            S   G PG PGLPG+ GD G PGI   G PG PG
Sbjct: 1047 SGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080



 Score =  400 bits (1029), Expect = e-111
 Identities = 251/586 (42%), Positives = 289/586 (49%), Gaps = 100/586 (17%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            +PGF G    GP      P P    PG PG  G  G PG  G+ G  GQPG  G PG  G
Sbjct: 764  LPGFKGAL--GPKGDRGFPGP----PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGL--PGFPGLHGMPGSKGEMGAKGD 540
            I G  G PG PGI G  G PG  G PG  GD G  GL  PG PG  G PG  G  G  G 
Sbjct: 818  I-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 541  KGSPGFYGKKGA------KGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594
             GSPG  GK GA      KGE G  G PG PGP G PGR G  GL G  G +G+ G PG 
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936

Query: 595  PGQDGTRGEPGIPGFPG--NRGLMGQKGE------------IGPPGQQGKKGAPGMPGLM 640
             G+ G++GEPG+PG PG  +  L+G KGE             GP G QG  G PG PGL 
Sbjct: 937  TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLS 996

Query: 641  GSNGSPGQPGTPGSKGSKGEPGI------------QGMPGASGLKGEPGATGSPGEPGYM 688
            G  G PG PG  G+ G  G+PG+             G PG  G++G PG +G PG+PG  
Sbjct: 997  GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056

Query: 689  GLPGIQGKKGDKG--NQGEKGIQGQKGENGRQGIPGQQGIQGH------HGAKGERGEKG 740
            GLPG +G KGD G  + G  G+ G KGE G  G PG  GI+G        G  G  G KG
Sbjct: 1057 GLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116

Query: 741  EPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGP---------QGPPGLDGKPGREFSEQ 791
            +PG+ G  G+ G  G  G+ GP G  G PG+PGP          GPPG  GKPG+     
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ----- 1171

Query: 792  FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRD 851
                   D I        + G+           G+PG PG PG  G +G  GLPG+PG  
Sbjct: 1172 -------DGIPGPAGQKGEPGQ--------PGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 852  GVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPP------------GPEG 899
            G+PG  G PG  G  G++G PG  G  G    G  G  GP GPP            GPEG
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEG 1276

Query: 900  PPGI----------SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
            PPG+             G PG PGLPG  GD G PG+QG PG PG+
Sbjct: 1277 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1322



 Score =  395 bits (1014), Expect = e-109
 Identities = 246/553 (44%), Positives = 281/553 (50%), Gaps = 91/553 (16%)

Query: 436 DVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQ---PGQDGKPGYQGIAGTPGVPGS 492
           D G T   CI      G+ GP G PGLPG PG PG    PGQ G+ G  G  G  G+PG 
Sbjct: 476 DKGDTCFNCI----GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 493 PGIQGARGLPGYKGE-------PGRDGDKGDRGLPGFPGLHGMPGSKGE---MGAKGDKG 542
           PG  GA G PG KGE       PG  GDKG+ G PG PGL G+PG+ G+    G  G KG
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 543 SPGFYGKKGAKGEKGNAGFPGLP---GPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDG 599
            PG    KG +G  GN G PGLP   GP G PG  G  G +G  G +G AG+PG PG  G
Sbjct: 592 EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 600 TRGEPG----IPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP--GTPG 653
            +G+PG     PG PG  G  G+ G++G PG  G  G PG+PG+ GS G PG P  G PG
Sbjct: 651 PKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPG 710

Query: 654 SKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMG--------LPGIQGKKGDKGNQGE 705
             G KG PGI G PGA G  G  G  G PG PG+ G        LPG  G  G  G +G 
Sbjct: 711 PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA 770

Query: 706 KGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGP 765
            G +G +G  G  G PG+ G+ G  G KG+ G  G+PG  G  G  G       +G  GP
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-------IGVQGP 823

Query: 766 KGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHG 825
            G PG PGP G PGL G PG +           D     L V    G          + G
Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEK----------GDPGPPGLDVPGPPG----------ERG 863

Query: 826 SPGIPGPPGPIGPEGPRGLPGLPGRDGVPGL---------------VGVPGRPGVRGLK- 869
           SPGIPG PGPIGP G  GLPG  G  G PG                +G+PGR GV GLK 
Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923

Query: 870 --------GLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDH 921
                   GLPG  GEKGS+     GE G PGPPGP  P  +  +G  G+PGLPG  G  
Sbjct: 924 DDGLQGQPGLPGPTGEKGSK-----GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS 978

Query: 922 GKPGIQGQPGPPG 934
           G  G QG PG PG
Sbjct: 979 GPKGYQGLPGDPG 991



 Score =  392 bits (1006), Expect = e-108
 Identities = 253/597 (42%), Positives = 289/597 (48%), Gaps = 96/597 (16%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPG-------------YPG 470
           PGF GE        G    P I  PG PGL G  G PGLPG PG              PG
Sbjct: 399 PGFPGE----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 471 QPGQDGKPGYQGIAGTPGV-------------------PGSPGIQGARGLPGYKGEPGRD 511
            PG  G PG +G+ G  GV                   PG PG+ G  G PG  G PG+ 
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 512 GDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPG----FYGKKGAKGEKGNAGFPGLPGP 567
           G+KG  G  G  GL G+PG+ G  G  G KG PG    F G KG KGE G+ G PGLPG 
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 568 AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQ 627
            G PG+   DGL G PG KGE G     G+ G  G PG+PG PGN G MG  G  GPPG 
Sbjct: 575 PGTPGQ---DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGP 630

Query: 628 QGKKGA------PGMPGLMGSNGSPGQ----PGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
            G+KG       PG PG+ G  G PGQ    PG PG  G+ G  G  G+PG  GL G+PG
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPG 690

Query: 678 ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             G PG  G  G+PGI    G  G  G KG  G  G  G  G PG+ G++G  G  G  G
Sbjct: 691 LPGIPGSKGEPGIPGI----GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 738 EKGEPG--VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQ 795
            KGEPG  + G  G  G  G  G +GP G +G PG PGP G  GLDG PG +        
Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPK-------- 798

Query: 796 VCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPG 855
              DV     P  +    +      +   G PG PG PGPIG  G  G+PG  G  G PG
Sbjct: 799 --GDVGPNGQPGPMGPPGLPG----IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852

Query: 856 L-----------VGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGP 900
           L            G+PG PG  G  G PG  G+ G+ GF    G  G  GPPGPPGP G 
Sbjct: 853 LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 901 PGIS-------KEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDP 950
           PG S        +G  G PGLPG  G+ G  G  G PGPPG  DP+L  S   + +P
Sbjct: 913 PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969



 Score =  385 bits (990), Expect = e-107
 Identities = 252/647 (38%), Positives = 301/647 (46%), Gaps = 152/647 (23%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGN------------------ 465
           PG  G  L GP+ +   P P I PPG PGL GP G PGLPG                   
Sbjct: 179 PGIQG--LPGPTGI---PGP-IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQ 232

Query: 466 -----PGYPGQ-------------------PGQDGKPGYQGIAGTPGVPGSP-GIQGARG 500
                PG PGQ                   PG  G PG  GI G PG PG   G +G +G
Sbjct: 233 GLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG 292

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAK------- 553
            PG +G+PG+DG+ G  G+PG PG  G PG  G  G KG KG  G  G  G         
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTG 352

Query: 554 ---GEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
              GEKGN G PGLPG  GE          G PG +G  G PG PG     G PG PGFP
Sbjct: 353 ITIGEKGNIGLPGLPGEKGE---------RGFPGIQGPPGLPGPPGA-AVMGPPGPPGFP 402

Query: 611 GNRGLMGQKGEIG-----PPGQQGKKGAPGMPGLMG-------------SNGSPGQPGTP 652
           G RG  G +G  G     PPG  G+ GAPG+PG  G               G PG PG+P
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 653 GSKGSKGEPGIQGMPG----------ASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN 702
           G KG +GE G++G  G           SG  G+PG  G PG PG +G PG +G+KG  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 703 QGEKGIQGQKGENGRQGIPGQQGIQGH----HGAKGERGEKGEPGVRGAIGSKGESGVDG 758
            G KG+ G  G  G  G PG +G  G      G KG++GE G PG  G  G  G  G DG
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 759 LMGPAGPKGQPG------DPGPQGPPGLDGKPGR-------------EFSEQFIRQVCTD 799
           L G  GPKG+PG      + GP G PGL G PG                 E+ I+ V  +
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 800 VIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGL--- 856
             +  +P     G   +    ++Q G PG+PG PG  G  G  G PGLPG+ G+PG+   
Sbjct: 643 PGQPGIP-----GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 857 --------VGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEG 907
                   +G+PG PG +G  G+PG  G  G+ G  G  G  GPPG PGP+G PG +  G
Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPG 757

Query: 908 PPGDP---------------GLPGKDGDHGKPGIQGQPGPPGICDPS 939
           PPG P               G PG  G  G+ G+ G PGP G   P+
Sbjct: 758 PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804



 Score =  377 bits (968), Expect = e-104
 Identities = 229/519 (44%), Positives = 257/519 (49%), Gaps = 61/519 (11%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICP-----PGKPGLQGPKGDPGLPGNPGYPGQPGQDGK 477
            +PG  G  ++GP      P     P     PG PG  GPKG+PGLPG PG  G PG  G 
Sbjct: 971  LPGIPG--VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 478  PGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRG-----LPGFPG------LH 526
             G  G  G  GV G PG  G  G PG  G PG+ GDKGD G     LPG PG      L 
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 527  GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586
            G PG+ G  G+ GD G PG  G  GAKG+ G  GFPG PGP G  G  G  G  G PG  
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148

Query: 587  GEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS- 645
            G  G  G PGQ G  GE G PG  G  G  GQKGE G PG  G  G PG+PGL G  G  
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDG 1207

Query: 646  --PGQPGTPGSKGSKGEPGIQGMPGASGL--------------KGEPGATGSPGEPGYMG 689
              PG PG PG  G KGEPG  G PG  G               KG PG  G PG PG  G
Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTG 1267

Query: 690  LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIG 749
              G+ G +G  G  G  GI+G+KG  G+ G+PG  G++G  G  G +G  G PG+ G  G
Sbjct: 1268 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1327

Query: 750  SKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLL 809
              G  GV G  G  GP G PG  GP+G PGL G PG                   LP   
Sbjct: 1328 DPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPP----------------GLPGPS 1371

Query: 810  QSGRIRNCDHCLSQHGSPGIPGPPGPIG---PEGPRGLPGLPGRDGVPGLVGVPGRPGVR 866
                I   D      G PGIPG PG  G   P+GP+GLPG  G  G PG  G+PG  G  
Sbjct: 1372 GQSIIIKGDA-----GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG 1426

Query: 867  GLKGLPGRNGEKGSQGF-GYPGEQGPPGPPGPEGPPGIS 904
            G KG PG  G+ G++G  G PG  G  GPPGP G   ++
Sbjct: 1427 GRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465



 Score =  375 bits (964), Expect = e-104
 Identities = 249/633 (39%), Positives = 287/633 (45%), Gaps = 140/633 (22%)

Query: 423 IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGL------------------PG 464
           +PG  G    GP  +   P P   P G+ G +G +G+PG                   PG
Sbjct: 262 LPGDRGP--PGPPGIRGPPGP---PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 465 NPGYPGQPGQDGKPGYQGIAGTPGVP-------------GSPGIQGARGLPGYKGEPGRD 511
           +PGYPG+PG+DG+ G +G  G PG P             G  G  G  GLPG KGE G  
Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 512 GDKGDRGLPGFPGL-----HGMPGSKGEMGAKGDKGSPGFY--GKKGAKGEKGNAGFPGL 564
           G +G  GLPG PG       G PG  GE G KGD+G PG    G  G  G+ G  G PG 
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436

Query: 565 PGPA----------------GEPGRHGKDGLMGSPGFKGE-------------AGSPGAP 595
           PGPA                G PG  G  GL G  G KG+             +G PG P
Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP 496

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSP--------- 646
           G  G  G PG  GFPG +G  GQ G  GP G  G  GAPG PG  GS G P         
Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 647 -------GQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA------TGSPGEPGYMGLP-- 691
                  G PG PG  G  G PG  G+PG  G KGEPG        G PG PG  GLP  
Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616

Query: 692 ---------------GIQGKKGDKGNQGEKGIQGQKG-------ENGRQGIPGQQGIQGH 729
                          G +G +G  GN G+ GI G KG       + G+ G+PG  G  G 
Sbjct: 617 IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 676

Query: 730 HGAKGERGEKGEPGVRGAIGSKGESGVD--GLMGPAGPKGQPGDPGPQGPPGLDGKPGRE 787
            G  G+ G  G+PG+ G  GSKGE G+   GL GP GPKG PG PGP G PG  G+ G E
Sbjct: 677 VGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE 736

Query: 788 FSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGL 847
                             P      +           G PG+PG  G +GP+G RG PG 
Sbjct: 737 GPPG--------------PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782

Query: 848 PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGI---- 903
           PG  G  GL G+PG  G  G  G PG  G  G  G G  G  GPPG PGP G PG+    
Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 904 SKEGPPGDPGL--PGKDGDHGKPGIQGQPGPPG 934
            ++G PG PGL  PG  G+ G PGI G PGP G
Sbjct: 843 GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875



 Score =  370 bits (949), Expect = e-102
 Identities = 248/646 (38%), Positives = 292/646 (45%), Gaps = 172/646 (26%)

Query: 439 STPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSP---GI 495
           S  + C C  G  G +G +G PGL G+PG PG PG +G PG +G  G  G+PG P   GI
Sbjct: 33  SPGSKCDCS-GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGI 91

Query: 496 QGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGE 555
           +G  GLPG+ G PG  G  G  G PG  G+ G  G+KGE G  G  G PG  G  G  G 
Sbjct: 92  RGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 556 KGNAGFPG------LPGPAGEPGRHGKDGLMGSP---GFKGEAGSPGAPGQDGTRGEPGI 606
            G  G PG      LPGP G PG  G  G+ G P   G  G  G PG PG  G  G PG+
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGL 211

Query: 607 PGFPGNRGL-----MGQKGE------IGPPGQ-------------------QGKKGAPGM 636
           PG  GN GL      G+KGE       GPPGQ                    G +G PG 
Sbjct: 212 PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 637 PGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGK 696
           PG+ G  G PG  G  G KG +GEPG +G PG  G  G+PG  G PG+PGY G PG  G+
Sbjct: 272 PGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE 329

Query: 697 K-------------------------GDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG 731
           K                         G+KGN G  G+ G+KGE G  GI G  G+ G  G
Sbjct: 330 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 732 A-----------KGERGEKGE--------PGVRGAIGSKGESGVDGLMGPAGPKGQPGD- 771
           A            GERG+KG+        PG  G  G  G  G+ G  GPAGP   P D 
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 772 ---PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCL------- 821
              PGP GPPG  G  G +  EQ ++    D                 C +C+       
Sbjct: 450 ICEPGPPGPPGSPGDKGLQ-GEQGVKGDKGD----------------TCFNCIGTGISGP 492

Query: 822 -SQHGSPGIPGPPGPI------------GPEGPRGLPGLP-------------------- 848
             Q G PG+PGPPG +            G  GP+GLPG+P                    
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 849 -----------GRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPP-- 895
                      G  G PGL G+PG PG  GL GLPG  GE G  G  + GE+GPPG P  
Sbjct: 553 FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG--GITFKGERGPPGNPGL 610

Query: 896 -------GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                  GP GPPG    GP G+ G+ G  G+ G+PGI G  G PG
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656



 Score =  295 bits (756), Expect = 1e-79
 Identities = 195/484 (40%), Positives = 226/484 (46%), Gaps = 100/484 (20%)

Query: 496 QGARGLPGYKGEPGR----DGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKG 551
           Q A     Y   PG      G KG++G  GFPGL G PG             PGF G +G
Sbjct: 22  QPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGL------------PGFPGPEG 69

Query: 552 AKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611
             G +G  G  G+PGP G  G  G  GL   PGF G  G PG PG DG  G  GIPG  G
Sbjct: 70  PPGPRGQKGDDGIPGPPGPKGIRGPPGL---PGFPGTPGLPGMPGHDGAPGPQGIPGCNG 126

Query: 612 NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS---PGQPGTPGSKGSKGEPGIQGMPG 668
            +G  G  G  G PG QG  G PG+PG+ G  GS      PG  G+ G  G PGIQG+PG
Sbjct: 127 TKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPG 186

Query: 669 ASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQG 728
            +G+   PG  G PG PG MG PG  G  G KGN G    QG KGE G      +QG+QG
Sbjct: 187 PTGI---PGPIGPPGPPGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKG------EQGLQG 236

Query: 729 HHGAKGERGEKGEP-------GVRGAIGSKGESGVDGLMGPAGPKG-QPGDPGPQGPPGL 780
             G  G+  E+  P       G +G  G +G  G  G+ GP GP G + G+ G QG PG 
Sbjct: 237 PPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 781 DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG 840
            GKPG++                                   ++G PGIPG PG  G  G
Sbjct: 297 RGKPGKD----------------------------------GENGQPGIPGLPGDPGYPG 322

Query: 841 PRGLPGLPGRDGVPGLVGVPG----RPGV------RGLKGLPGRNGEKGSQGFGYPGEQG 890
             G  G  G+ G  G  G PG    RPG       +G  GLPG  GEKG +GF  PG QG
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF--PGIQG 380

Query: 891 PPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQ--------------GQPGPPGIC 936
           PPG PGP G   +   GPPG PG  G+ GD G PGI               G PGPPG  
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 937 DPSL 940
            P +
Sbjct: 441 GPHI 444


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  392 bits (1008), Expect = e-109
 Identities = 229/539 (42%), Positives = 275/539 (51%), Gaps = 68/539 (12%)

Query: 448  PGKPGLQGPKGDPG--LPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYK 505
            PGKPGL G KG+P   +PG PG PG PG+ G  G  G  G PG+PG PG  G  GL G +
Sbjct: 732  PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791

Query: 506  GEPGR--------------DGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKG--------- 542
            G+PG+              +G +G +GLPG  GL G  G +G+ G KGD G         
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851

Query: 543  -----SPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ 597
                 SPG  G +G  G  G  G+PG PG  G PG  G  G+MG PG  G  G PG PG 
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 598  DGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQ---------GKKGAPGMPGLMGSNGSPGQ 648
             G RG PGIPG  G RG  G KGE G  G           G KG PG+ G  G+ G  G 
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 649  PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
             G PG  G KG  G+ G  G  G +G+ G+TG+PGEPG  G+PG  G  G  G++G++G 
Sbjct: 972  RGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031

Query: 709  QGQKGENGRQGIPGQQGIQGHHG--------AKGERGEKGEPGVRGAIGSKGESGVDGLM 760
             G  G  GR G+PG  G+QG  G          G  G  G+PG+ G +G KGE G  G  
Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPP 1091

Query: 761  GPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHC 820
            G  GP G  G PG  G PGL GKPG             D+    +  LL    IR     
Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPH----------GDLGFKGIKGLLGPPGIR----- 1136

Query: 821  LSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVG-VPGRPGVRGLKGLPGRNGEKG 879
                G PG PG PGP+G  G +G  G+PG  G  G  G +   PG RG  G  G  G++G
Sbjct: 1137 -GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 880  SQGF-GYPGEQGPPGPPGPEGPPGISK-EGPPGDPG--LPGKDGDHGKPGIQGQPGPPG 934
            + GF G PG +G  G  GP GP GI    GPPG PG  +PG+ G+ G PG +G PG PG
Sbjct: 1196 APGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254



 Score =  391 bits (1005), Expect = e-108
 Identities = 248/575 (43%), Positives = 291/575 (50%), Gaps = 86/575 (14%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK------ 477
            PG  G  L+     G T +P I  PG  G  GP G  G PGNPG  G PG+DG       
Sbjct: 841  PGIPG--LDRSGFPGETGSPGI--PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 478  PGYQGIAGTPGVPGSPGIQGARGLPGYKGE---PGRDGDKGDRGLPGFPGLHGMPGSKGE 534
            PG  G  G PG PG+PG +G+ G+PG KG+   PG  G++GD+G PG   +  + G KGE
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 535  MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHG---------KDGLMGSPGF 585
             G KG  G+PG  G +G  G  G  G  GLPGPAG PG  G         + GL G PG 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 586  KGEAGSPGAPGQDGTRGEPGI---PGFPGNRGLMGQKGEIG-----PPGQQGKKGAPGMP 637
             G  G PG+ G+ GT G PG    PG PG  GL G KGE G      PG  G  G PG+P
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 638  GLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGL---PGIQ 694
            G MG  G  GQPG PG  G  G  G  G PG+ GL G+PG  G  G  G  GL   PGI+
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 695  GKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGA-KGERGEKGEPGVRGAIGSKGE 753
            G  G  G  G  G  G +G+ GR GIPG  G +G  G  +   G +G PG +GA   KG+
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA---KGD 1193

Query: 754  SGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGR 813
             G  G  G  G KG  GD GP+GP G++G PG                   LP  +  G+
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP----------------GLPGAIIPGQ 1237

Query: 814  IRNCDHCLSQHGSPGIPGPPGP--------------IGPEGPRGLPGL------PGRDGV 853
              N     S+ GSPG PGPPGP              +G  GP+G PG       PGR G 
Sbjct: 1238 TGNRGPPGSR-GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA 1296

Query: 854  PGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPG----------I 903
            PG  G+PG  G  G +G PG  GEKG+ GF   G  GPPGP GP+GPPG          I
Sbjct: 1297 PGTPGLPGPRGDPGFQGFPGVKGEKGNPGF--LGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 904  SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            S  G PG PG PG+ G  G+PG  G PG  G C P
Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  378 bits (971), Expect = e-104
 Identities = 247/613 (40%), Positives = 294/613 (47%), Gaps = 111/613 (18%)

Query: 423  IPGFNGEC-LNG-PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQP-GQDGKPG 479
            IPG  G   L G P   G+T  P     G PG  G +GDPGL G  G   QP GQ G PG
Sbjct: 500  IPGRQGAAGLKGSPGSPGNTGLP-----GFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG 554

Query: 480  YQGIAGTPG---VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536
              G+ G PG   + G PG  G +GLPG KGE    G+KGD+G PG PG  G PG  G  G
Sbjct: 555  DPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614

Query: 537  AKG--DKGSPGFYGKKGAKGEKGNAG-------------FPGLPGPAGEPGRHGKDGLMG 581
              G   +G PG  G +G  G  G  G              PG PGP G PG  G  G  G
Sbjct: 615  PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG 674

Query: 582  SPGFKGEAGSPGAPGQDGTRGEPGI-----PGFPGNRGLMGQKGEIGPPGQQGKKGAPGM 636
             PG  G+ G PG PG DG  G PGI     PG  G++G  G KG +G PG+ G+ G PG 
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734

Query: 637  PGLMGSNGSP--------GQPGTPGSKGSKGE---------PGIQGMPGASGLKGEPGAT 679
            PGL G+ G P        G PG PG +G+ GE         PG+ G PG  GL G  G  
Sbjct: 735  PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 680  GSPGEPGYMGLPG--IQGKKGDKGNQGEKGIQGQKGENG--------------RQGIPGQ 723
            G PG PG  G PG  I+G +G +G  G  G++GQ+G  G              R G PG+
Sbjct: 795  GQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGE 854

Query: 724  QG---IQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMG------PAGPKGQPGDPGP 774
             G   I GH G  G  G++G PG  G +G  GE GV G+MG      P GP G PG PG 
Sbjct: 855  TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914

Query: 775  QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPG 834
            +G PG+ G  G         Q  T   + +       G      H +   G PG+ G  G
Sbjct: 915  RGSPGIPGVKG---------QRGTPGAKGEQGDKGNPGP-SEISHVIGDKGEPGLKGFAG 964

Query: 835  PIGPEGPRGLPGLPGRDGVPGL---------------VGVPGRPGVRGLKGLPGRNGEKG 879
              G +G RG+PG+PG  G+ GL                G PG PG+RG+ G  G  G  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024

Query: 880  SQG----FGYPGEQGPPGPPG------PEGPPGIS---KEGPPGDPGLPGKDGDHGKPGI 926
            S+G     G+PG  G PG PG       +G PG S   + GPPG  G PG  GD GK G 
Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 927  QGQPGPPGICDPS 939
             GQPGPPG   P+
Sbjct: 1085 MGQPGPPGHLGPA 1097



 Score =  375 bits (963), Expect = e-103
 Identities = 234/551 (42%), Positives = 281/551 (50%), Gaps = 70/551 (12%)

Query: 447 PPGKPG-----LQGP------KGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGI 495
           PPG PG     L GP      KG+ G  G  G PG PG  G PG +      G PG PG+
Sbjct: 237 PPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-ESYGSEKGAPGDPGL 295

Query: 496 QGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGA---------------KGD 540
           QG  G  G  G PG +G KG+RG PG  G  G+ G KG++G                KGD
Sbjct: 296 QGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGD 355

Query: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600
           +G+PG  G +GA+G +G +G PG+PG  G   R G  G  G PG KG  G  G PG+D  
Sbjct: 356 EGTPGPPGPRGARGPQGPSGPPGVPGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAM 414

Query: 601 RGEPGIPGFPGNRGLMGQKGEIGPPGQ-QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKG 659
            G PG PG  G+ GL G  G  GPPG    +KG PG  GL G  GSPG PG  G KG  G
Sbjct: 415 -GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPG 473

Query: 660 -----------EPGIQGMPGASGLKGEPGATG------SPGEPGYMGLPGIQGKKGDKGN 702
                       PG+ G+PG  G+KG PG  G      SPG PG  GLPG  G  G    
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGA--- 530

Query: 703 QGEKGIQGQKGEN----GRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDG 758
           QG+ G++G+KGE     G+ G+PG  G++G  G KG  G  G PGV+G  G KGE  + G
Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590

Query: 759 LMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCD 818
             G  GP G PG PG  GP G  G PG     +   Q    V  A  P   ++G      
Sbjct: 591 EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP-GEAGPRGELS 649

Query: 819 HCLSQHGSPGIPGPPGPIGPEGPRGL---------PGLPGRDGVPGL--VGVPGRPGVRG 867
                 G PG PGPPG  GP+GP G+         PGLPG DG PG+  +G PG PG +G
Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 868 LKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGK---DGDHGK 923
            +G PG  G  G  G  G PG  G PG PG +G P ++  G PG PG PG+    G+HG+
Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 924 PGIQGQPGPPG 934
            G+ G PG PG
Sbjct: 770 IGLPGLPGLPG 780



 Score =  367 bits (941), Expect = e-101
 Identities = 233/536 (43%), Positives = 268/536 (50%), Gaps = 55/536 (10%)

Query: 439  STPAPCIC-PPGKPGLQGPKGDPGLPGNPGY---PGQPGQDGKPGYQGIAGTPGVPGSPG 494
            STP P    PPG PG  GP+G PG+PG+ G    PG PG DG+PG  GI    G PG PG
Sbjct: 651  STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI----GFPGPPG 706

Query: 495  IQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGE--MGAKGDKGSPGFYGKKGA 552
             +G +G PG KG  G  G  G+ GLPG PGL   PG+KGE  +   G  G+PGF G++G 
Sbjct: 707  PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGN 763

Query: 553  KGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ--DGTRGEPGIPGFP 610
             GE G  G PGLPG  G PG  G DG  G PG  G  G  G PG+  +G RG  G+PG  
Sbjct: 764  SGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823

Query: 611  GNRGLMGQKGEIGP--------------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG 656
            G +G  G++G+ GP              PG+ G  G PG  G MG  G  G PG PG  G
Sbjct: 824  GLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG 883

Query: 657  SKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENG 716
              GE G+ GM G  G  G PG  G+PG PG  G PGI G KG +G  G KG QG KG  G
Sbjct: 884  PPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPG 943

Query: 717  RQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776
               I    G +G  G KG  G  GE G RG  G  G  G+ GL GPAGP G  GD G  G
Sbjct: 944  PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTG 1003

Query: 777  PPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI 836
             PG  G  G   S   +    +   R  L    ++GR             PG+PG  G  
Sbjct: 1004 NPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR-------------PGLPGIHGLQ 1050

Query: 837  GPEGPRGL-----PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQG 890
            G +G  G      PG PG  G PGL G  G+ G  G  G PG  G  G +G  G PG  G
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 891  PPGPPGPEGPPGISKE----GPPG---DPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
             PG PGP G  G        GPPG    PGLPG  G  G  GI+G  G  GI  P+
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA 1166



 Score =  358 bits (920), Expect = 1e-98
 Identities = 244/621 (39%), Positives = 293/621 (47%), Gaps = 131/621 (21%)

Query: 432 NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQD--GKPGYQGIAGTPGV 489
           +GP  V  +P        +PGL+G  G PGL G+ G  G+PG+D  G PG  G AG+PG+
Sbjct: 374 SGPPGVPGSPGS-----SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGL 428

Query: 490 PGSPGIQGA-------------RGLPGYKGEPGR---DGDKGDRGL--------PGFPGL 525
           PGSPG  G               GLPGY G PG    DG KG+ GL        PG PGL
Sbjct: 429 PGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGL 488

Query: 526 HGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGK-------DG 578
            G+PG  G  G  G +G+ G  G  G+ G  G  GFPG PG  G+PG  G+       +G
Sbjct: 489 PGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG 548

Query: 579 LMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRG---LMGQKGEIGPPGQQGKKGAPG 635
            +G PG  G  G PG  G DG  G PG+ G PG +G   L G+KG+ GPPG  G  G+PG
Sbjct: 549 QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPG 608

Query: 636 M--------------PGLMGSNGSPGQPGTPGSKGSKGE-------------------PG 662
                          PGL G+ G PG PG PG  G +GE                   PG
Sbjct: 609 PAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668

Query: 663 IQG---MPGASGLKGEPGATGSPGEPGY--MGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
            QG   +PG+ G  G+PG  G  GEPG   +G PG  G KGD+G  G KG  G  G+ G 
Sbjct: 669 PQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGE 728

Query: 718 QGIPGQQGIQGHHGA-----------------KGERGEKGEPGVRGAIGSKGESGVDGLM 760
            G+PG+ G+ G  G                  +G  GE GE G+ G  G  G  G +GL 
Sbjct: 729 PGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLD 788

Query: 761 GPAGPKGQPGDPGPQGPPG--LDGKPGREFSEQFIRQVCTDVIRAQLPVLL----QSGRI 814
           GP G  GQPG PG QGPPG  ++G  G +                 LP L     Q GR 
Sbjct: 789 GPRGDPGQPGPPGEQGPPGRCIEGPRGAQ----------------GLPGLNGLKGQQGRR 832

Query: 815 RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                     G PGIPG     G  G  G PG+PG  G  G +G  G PG  G+ G PG 
Sbjct: 833 GKT----GPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 875 NGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           +G  G  GF  PG  GPPGPPG  G PG       G PG+PG  G  G PG +G+ G  G
Sbjct: 888 DGVIGMMGF--PGAIGPPGPPGNPGTPG-----QRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 935 ICDPSLCFSVIA-RRDPFRKG 954
              PS    VI  + +P  KG
Sbjct: 941 NPGPSEISHVIGDKGEPGLKG 961



 Score =  346 bits (887), Expect = 7e-95
 Identities = 235/565 (41%), Positives = 274/565 (48%), Gaps = 93/565 (16%)

Query: 444 CICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG---SPGIQGARG 500
           C C  G  G +G KG PG PG+PG  G  G +G PG QG  G PG+PG   S G++G  G
Sbjct: 39  CFCD-GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISG 97

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS------PGFYGKKGAKG 554
           LPG+ G PG  G  G+ G  G  G+ G  GSKGE G  G  G+      PG  G KG KG
Sbjct: 98  LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKG 157

Query: 555 -----------EKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
                       KG+ G PG PGP G PG  G  G +G PG  G  G PGA G  G +G 
Sbjct: 158 APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGH 217

Query: 604 PG--IPGFPGNRGLMGQKGEIGPPG-----------QQGKKGAPGMPGLMGSNGSPGQPG 650
            G  + G  G RG+ G  G  GPPG           +   KG  G  G MG  G PG  G
Sbjct: 218 MGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277

Query: 651 TPG-----SKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGE 705
            PG      KG+ G+PG+QG PG  G+ G PG+ G  G  G+ GL G  G KG KG+ G 
Sbjct: 278 LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 706 KGIQG---------QKGENGRQGIPGQQGIQGHHGAKGERGEKG-----EPGVRGAIGSK 751
            G +G         +KG+ G  G PG +G +G  G  G  G  G      PG+RGA G  
Sbjct: 338 PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397

Query: 752 GESGVDGLMGPAG--PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLL 809
           G  G  G  G  G    G PG PG  G PGL G PG       I      V R   P   
Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI------VFRKGPP--- 448

Query: 810 QSGRIRNCDHCLSQH-GSPGIPGPPGPIGPEG--------PRGLPGLPGRDGVPGLVGVP 860
                   DH L  + GSPGIPG  GP G  G          G PGLPG  G+ G+ G+P
Sbjct: 449 -------GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501

Query: 861 GRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGPPGPPGPEG----PPGISKEGPPGDPGLP 915
           GR G  GLKG PG  G  G  GF G+PG QG PG  G +G    P G  + G PGDPGL 
Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG--QVGVPGDPGLR 559

Query: 916 GK------DGDHGKPGIQGQPGPPG 934
           G+      DG  G PG++G PGP G
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKG 584



 Score =  330 bits (845), Expect = 5e-90
 Identities = 210/513 (40%), Positives = 251/513 (48%), Gaps = 82/513 (15%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPG---------------------QDGKPGYQGIAG 485
            PPG PG  G +G PG+PG  G  G PG                       G+PG +G AG
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 486  TPG------VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKG 539
             PG      VPG PG++G +GLPG  G PG  GD G  G PG PGL G+PGS G MG  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024

Query: 540  DKGS------------PGFYGKKGAKGEKGNAGF-----PGLPGPAGEPG------RHGK 576
             KG             PG  G  G +G+KG  G+     PG PGP G+PG      + G+
Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 577  DGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM 636
             G  G PG  G AG  GAPG  G+ G PG PG  G+ G  G KG +GPPG +G  G PG 
Sbjct: 1085 MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGF 1144

Query: 637  PGL---MGSNGSPGQPGTPGSKGSKGEPGI-QGMPGASGLKGEPGATGSPGEPGYMGLPG 692
            PG    MG  G  G+ G PG  G KGE G+ +  PG  G  G  GA G  G PG+ GLPG
Sbjct: 1145 PGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPG 1204

Query: 693  IQGKKGDKGNQGEKGIQGQKGENGRQG--IPGQQGIQGHHGAKGERGEKGEPGVRGA--I 748
             +G  GD G +G  GI+G  G  G  G  IPGQ G +G  G++G  G  G PG  G+  I
Sbjct: 1205 RKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI 1264

Query: 749  GSKGESGVDGLMGPAGPKGQPGD---------------PGPQGPPGLDGKPG---REFSE 790
            G KG+ G  G  GP GP G  GD               PGP+G PG  G PG    + + 
Sbjct: 1265 GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNP 1324

Query: 791  QFIRQVCTD-VIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPG 849
             F+  +     I  + P       +R     L     PG PGPPG  G  G +G PG PG
Sbjct: 1325 GFLGSIGPPGPIGPKGPP-----GVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379

Query: 850  RDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG 882
              G  G  G  G+PG  G  G PG  GEKG++G
Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKG 1412



 Score =  308 bits (788), Expect = 2e-83
 Identities = 192/433 (44%), Positives = 226/433 (52%), Gaps = 49/433 (11%)

Query: 551 GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
           GAKGEKG  GFPG PG  G+ G  G +GL G  G KG  G PG  G  G RG  G+PGF 
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 611 GNRGLMGQKGEIGP------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG-------- 656
           G+ GL G  G  GP      PG  G KG  G PGL G+ G PG PG  G KG        
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 657 ------SKGEPGIQGMPGASGLKGE---PGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707
                 +KG+PG+ G PG  GL G    PG  G PG PG+ G PG  G +G KG+ GE+ 
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 708 IQGQKGENGRQGIPGQQGIQGH-----HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGP 762
           I G KGE G +G+ G  G  G       G       KGE G +GA+G  G  G  GL G 
Sbjct: 223 I-GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 763 A--GPKGQPGDPGPQGPPGLDGKPGREFSE------QFIRQVCTDVIRAQLPVLLQSGRI 814
           +    KG PGDPG QG PG DG PG   SE       F   +  D I+ Q   +   G  
Sbjct: 282 SYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR 341

Query: 815 RNCDH--CLSQHGSPGIPGPPGP---IGPEGPRGLPGLPGRDGV--PGLVGVPGRPGVRG 867
              ++     + G  G PGPPGP    GP+GP G PG+PG  G   PGL G PG PG++G
Sbjct: 342 GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKG 401

Query: 868 LKGLPGRNGE--KGSQGF-GYPGEQGPPGPPGPEGPPG--ISKEGPPGDPGLPGKDGDHG 922
            KG  GR G+   G+ G  G  G  G PG PGP GPPG  + ++GPPGD GLPG  G  G
Sbjct: 402 SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461

Query: 923 KPGIQGQPGPPGI 935
            PG+ G  G PG+
Sbjct: 462 IPGVDGPKGEPGL 474



 Score =  290 bits (741), Expect = 6e-78
 Identities = 163/354 (46%), Positives = 186/354 (52%), Gaps = 15/354 (4%)

Query: 450  KPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPG 509
            +PG  GP GDPGLPG+ G  G+ GQ G PG+ G AG  G PGSPG  G  G PG  G+ G
Sbjct: 1063 RPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122

Query: 510  RDGDKGDRGLPGF---PGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
              G KG  G PG    PGL G PGS G MG +GD+G  G  G  G KGE G    P  PG
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP--PG 1180

Query: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMG-----QKGE 621
            P G PG  G  G  G+PGF G  G  GA G  G RG  GI GFPG  GL G     Q G 
Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGN 1240

Query: 622  IGPPGQQGKKGAPGMPGLMGSN-----GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEP 676
             GPPG +G  GAPG PG  GS+     G  G  G PG KG  G  G  G PG  G  G P
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300

Query: 677  GATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGER 736
            G  G  G+PG+ G PG++G+KG+ G  G  G  G  G  G  G+ G  G        G  
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360

Query: 737  GEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSE 790
            G  G PG  G  G  G  G  G +GP GP+G+PG  G  G PG  G+ G + S+
Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414



 Score =  270 bits (691), Expect = 4e-72
 Identities = 181/458 (39%), Positives = 211/458 (46%), Gaps = 91/458 (19%)

Query: 536 GAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP 595
           GAKG+KG  GF G  G+ G+KG  G  GLPGP G  G  G  GL GS G +G +G PG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSK 655
           G       PG+PG PGN G  G  G  G  G +G++G PG+PG +G  G PG  G  G K
Sbjct: 103 GS------PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 656 GS-----------KGEPGIQGMPGASGLKGEPG---ATGSPGEPGYMGLPGIQGKKGDKG 701
           G+           KG+PG+ G PG  GL G PG     G PG PG+ G PG  G +G KG
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 702 NQGEKGIQGQKGENGRQGIPGQQGIQGH-----HGAKGERGEKGEPGVRGAIGSKGESGV 756
           + GE+ I G KGE G +G+ G  G  G       G       KGE G +GA+G  G  G 
Sbjct: 217 HMGERVI-GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGP 275

Query: 757 DGLMGPA--GPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
            GL G +    KG PGDPG QG PG D                                 
Sbjct: 276 SGLPGESYGSEKGAPGDPGLQGKPGKD--------------------------------- 302

Query: 815 RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                        G+PG PG  G +G RG PGL G DG+ G  G  G PG RG       
Sbjct: 303 -------------GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349

Query: 875 NGEKGSQGFGYP----GEQGPPGPPGPEGPPGI------SKEGPPGDPGLPGKDGDHGKP 924
             EKG +G   P    G +GP GP GP G PG          G PG PGL G  G+ G+P
Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409

Query: 925 G--IQGQPGPPGIC-DPSLCFSVIARRDP----FRKGP 955
           G    G PG PG    P L  S      P    FRKGP
Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447



 Score =  250 bits (639), Expect = 4e-66
 Identities = 140/330 (42%), Positives = 179/330 (54%), Gaps = 44/330 (13%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
            PPG  G  GP+G PG PG+PG PG+PG  G  G++GI G   + G PGI+G  GLPG+ G
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG---LLGPPGIRGPPGLPGFPG 1146

Query: 507  EPGRDGDKGDRGLPGFPG----------LHGMPGSKGE---MGAKGDKGSPGFYGKKGAK 553
             PG  G +GD+G  G PG          L   PG +G     GAKGD+G+PGF G  G K
Sbjct: 1147 SPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRK 1206

Query: 554  GEKGNAG------FPGLPGPAGEPGR--HGKDGLMGSPGFKGEAGSPGAPGQDGT----- 600
            G  G+AG        G PGP G PG    G+ G  G PG +G  G+PG PG  G+     
Sbjct: 1207 GAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGI 1266

Query: 601  RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGS--- 657
            +G+ G  G PG +G  G  G++GPPG+ G  G PG+PG  G  G  G PG  G KG+   
Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGF 1326

Query: 658  ------------KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGE 705
                        KG PG++G PG   +   PG+ G PG PG  G+ G  G  G  GN G 
Sbjct: 1327 LGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGP 1386

Query: 706  KGIQGQKGENGRQGIPGQQGIQGHHGAKGE 735
             G +G+ G++G+ G PG  G +G+ G+KGE
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416



 Score =  209 bits (532), Expect = 1e-53
 Identities = 125/267 (46%), Positives = 136/267 (50%), Gaps = 15/267 (5%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            IPG  GE      + G   AP   P G PG QG KGD G PG PG PG+ G  G  G +G
Sbjct: 1162 IPGPAGE----KGETGLLRAPP-GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG 1216

Query: 483  IAGTPGVPGSPGIQGA--RGLPGYKGEPGRDGDKGDRGLPGFPGLH--GMPGSKGEMGAK 538
              G  G PG PG+ GA   G  G +G PG  G  G  G PG PG H  G+ G KG MG  
Sbjct: 1217 PTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP 1276

Query: 539  GDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQD 598
            G KG PG  G  G  G  G  G PGLPGP G+PG        G PG KGE G+PG  G  
Sbjct: 1277 GPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG------FQGFPGVKGEKGNPGFLGSI 1330

Query: 599  GTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSK 658
            G  G  G  G PG RG  G    I  PG  G  G PG PG+ G  G PG PG  G  G +
Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390

Query: 659  GEPGIQGMPGASGLKGEPGATGSPGEP 685
            G+PG  G PG  G  GE G  GS GEP
Sbjct: 1391 GKPGKDGKPGTPGPAGEKGNKGSKGEP 1417



 Score =  173 bits (438), Expect = 8e-43
 Identities = 114/299 (38%), Positives = 131/299 (43%), Gaps = 39/299 (13%)

Query: 658 KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
           KG+    G  G  G KG PG  GSPG+ G+ G  G+ G +G KG  G  G+ G KG  G 
Sbjct: 36  KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGI 95

Query: 718 QGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGP 777
            G+PG  G  G  G  G  G  G  GV G  GSKGE G  GL G  G    PG PG  G 
Sbjct: 96  SGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG---YPGIPGAAGL 152

Query: 778 PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIG 837
            G  G P +E   +                             L   G PG+PG PGP G
Sbjct: 153 KGQKGAPAKEEDIE-----------------------------LDAKGDPGLPGAPGPQG 183

Query: 838 PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRN--GEKGSQGFGYPGEQGPPGPP 895
             GP G PG  G  G PG  G PG  G RG KG  G    G KG +G      +G  GPP
Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGV-----KGLTGPP 238

Query: 896 GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKG 954
           GP G   ++  GP     L G+ GD G  G  G PGP G+   S      A  DP  +G
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  392 bits (1008), Expect = e-109
 Identities = 229/539 (42%), Positives = 275/539 (51%), Gaps = 68/539 (12%)

Query: 448  PGKPGLQGPKGDPG--LPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYK 505
            PGKPGL G KG+P   +PG PG PG PG+ G  G  G  G PG+PG PG  G  GL G +
Sbjct: 732  PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791

Query: 506  GEPGR--------------DGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKG--------- 542
            G+PG+              +G +G +GLPG  GL G  G +G+ G KGD G         
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851

Query: 543  -----SPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ 597
                 SPG  G +G  G  G  G+PG PG  G PG  G  G+MG PG  G  G PG PG 
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 598  DGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQ---------GKKGAPGMPGLMGSNGSPGQ 648
             G RG PGIPG  G RG  G KGE G  G           G KG PG+ G  G+ G  G 
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 649  PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
             G PG  G KG  G+ G  G  G +G+ G+TG+PGEPG  G+PG  G  G  G++G++G 
Sbjct: 972  RGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031

Query: 709  QGQKGENGRQGIPGQQGIQGHHG--------AKGERGEKGEPGVRGAIGSKGESGVDGLM 760
             G  G  GR G+PG  G+QG  G          G  G  G+PG+ G +G KGE G  G  
Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPP 1091

Query: 761  GPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHC 820
            G  GP G  G PG  G PGL GKPG             D+    +  LL    IR     
Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPH----------GDLGFKGIKGLLGPPGIR----- 1136

Query: 821  LSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVG-VPGRPGVRGLKGLPGRNGEKG 879
                G PG PG PGP+G  G +G  G+PG  G  G  G +   PG RG  G  G  G++G
Sbjct: 1137 -GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 880  SQGF-GYPGEQGPPGPPGPEGPPGISK-EGPPGDPG--LPGKDGDHGKPGIQGQPGPPG 934
            + GF G PG +G  G  GP GP GI    GPPG PG  +PG+ G+ G PG +G PG PG
Sbjct: 1196 APGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254



 Score =  391 bits (1005), Expect = e-108
 Identities = 248/575 (43%), Positives = 291/575 (50%), Gaps = 86/575 (14%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK------ 477
            PG  G  L+     G T +P I  PG  G  GP G  G PGNPG  G PG+DG       
Sbjct: 841  PGIPG--LDRSGFPGETGSPGI--PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 478  PGYQGIAGTPGVPGSPGIQGARGLPGYKGE---PGRDGDKGDRGLPGFPGLHGMPGSKGE 534
            PG  G  G PG PG+PG +G+ G+PG KG+   PG  G++GD+G PG   +  + G KGE
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 535  MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHG---------KDGLMGSPGF 585
             G KG  G+PG  G +G  G  G  G  GLPGPAG PG  G         + GL G PG 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 586  KGEAGSPGAPGQDGTRGEPGI---PGFPGNRGLMGQKGEIG-----PPGQQGKKGAPGMP 637
             G  G PG+ G+ GT G PG    PG PG  GL G KGE G      PG  G  G PG+P
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 638  GLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGL---PGIQ 694
            G MG  G  GQPG PG  G  G  G  G PG+ GL G+PG  G  G  G  GL   PGI+
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 695  GKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGA-KGERGEKGEPGVRGAIGSKGE 753
            G  G  G  G  G  G +G+ GR GIPG  G +G  G  +   G +G PG +GA   KG+
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA---KGD 1193

Query: 754  SGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGR 813
             G  G  G  G KG  GD GP+GP G++G PG                   LP  +  G+
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP----------------GLPGAIIPGQ 1237

Query: 814  IRNCDHCLSQHGSPGIPGPPGP--------------IGPEGPRGLPGL------PGRDGV 853
              N     S+ GSPG PGPPGP              +G  GP+G PG       PGR G 
Sbjct: 1238 TGNRGPPGSR-GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA 1296

Query: 854  PGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPG----------I 903
            PG  G+PG  G  G +G PG  GEKG+ GF   G  GPPGP GP+GPPG          I
Sbjct: 1297 PGTPGLPGPRGDPGFQGFPGVKGEKGNPGF--LGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 904  SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            S  G PG PG PG+ G  G+PG  G PG  G C P
Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  378 bits (971), Expect = e-104
 Identities = 247/613 (40%), Positives = 294/613 (47%), Gaps = 111/613 (18%)

Query: 423  IPGFNGEC-LNG-PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQP-GQDGKPG 479
            IPG  G   L G P   G+T  P     G PG  G +GDPGL G  G   QP GQ G PG
Sbjct: 500  IPGRQGAAGLKGSPGSPGNTGLP-----GFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG 554

Query: 480  YQGIAGTPG---VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536
              G+ G PG   + G PG  G +GLPG KGE    G+KGD+G PG PG  G PG  G  G
Sbjct: 555  DPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614

Query: 537  AKG--DKGSPGFYGKKGAKGEKGNAG-------------FPGLPGPAGEPGRHGKDGLMG 581
              G   +G PG  G +G  G  G  G              PG PGP G PG  G  G  G
Sbjct: 615  PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG 674

Query: 582  SPGFKGEAGSPGAPGQDGTRGEPGI-----PGFPGNRGLMGQKGEIGPPGQQGKKGAPGM 636
             PG  G+ G PG PG DG  G PGI     PG  G++G  G KG +G PG+ G+ G PG 
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734

Query: 637  PGLMGSNGSP--------GQPGTPGSKGSKGE---------PGIQGMPGASGLKGEPGAT 679
            PGL G+ G P        G PG PG +G+ GE         PG+ G PG  GL G  G  
Sbjct: 735  PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 680  GSPGEPGYMGLPG--IQGKKGDKGNQGEKGIQGQKGENG--------------RQGIPGQ 723
            G PG PG  G PG  I+G +G +G  G  G++GQ+G  G              R G PG+
Sbjct: 795  GQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGE 854

Query: 724  QG---IQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMG------PAGPKGQPGDPGP 774
             G   I GH G  G  G++G PG  G +G  GE GV G+MG      P GP G PG PG 
Sbjct: 855  TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914

Query: 775  QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPG 834
            +G PG+ G  G         Q  T   + +       G      H +   G PG+ G  G
Sbjct: 915  RGSPGIPGVKG---------QRGTPGAKGEQGDKGNPGP-SEISHVIGDKGEPGLKGFAG 964

Query: 835  PIGPEGPRGLPGLPGRDGVPGL---------------VGVPGRPGVRGLKGLPGRNGEKG 879
              G +G RG+PG+PG  G+ GL                G PG PG+RG+ G  G  G  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024

Query: 880  SQG----FGYPGEQGPPGPPG------PEGPPGIS---KEGPPGDPGLPGKDGDHGKPGI 926
            S+G     G+PG  G PG PG       +G PG S   + GPPG  G PG  GD GK G 
Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 927  QGQPGPPGICDPS 939
             GQPGPPG   P+
Sbjct: 1085 MGQPGPPGHLGPA 1097



 Score =  375 bits (963), Expect = e-103
 Identities = 234/551 (42%), Positives = 281/551 (50%), Gaps = 70/551 (12%)

Query: 447 PPGKPG-----LQGP------KGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGI 495
           PPG PG     L GP      KG+ G  G  G PG PG  G PG +      G PG PG+
Sbjct: 237 PPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-ESYGSEKGAPGDPGL 295

Query: 496 QGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGA---------------KGD 540
           QG  G  G  G PG +G KG+RG PG  G  G+ G KG++G                KGD
Sbjct: 296 QGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGD 355

Query: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600
           +G+PG  G +GA+G +G +G PG+PG  G   R G  G  G PG KG  G  G PG+D  
Sbjct: 356 EGTPGPPGPRGARGPQGPSGPPGVPGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAM 414

Query: 601 RGEPGIPGFPGNRGLMGQKGEIGPPGQ-QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKG 659
            G PG PG  G+ GL G  G  GPPG    +KG PG  GL G  GSPG PG  G KG  G
Sbjct: 415 -GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPG 473

Query: 660 -----------EPGIQGMPGASGLKGEPGATG------SPGEPGYMGLPGIQGKKGDKGN 702
                       PG+ G+PG  G+KG PG  G      SPG PG  GLPG  G  G    
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGA--- 530

Query: 703 QGEKGIQGQKGEN----GRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDG 758
           QG+ G++G+KGE     G+ G+PG  G++G  G KG  G  G PGV+G  G KGE  + G
Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590

Query: 759 LMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCD 818
             G  GP G PG PG  GP G  G PG     +   Q    V  A  P   ++G      
Sbjct: 591 EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP-GEAGPRGELS 649

Query: 819 HCLSQHGSPGIPGPPGPIGPEGPRGL---------PGLPGRDGVPGL--VGVPGRPGVRG 867
                 G PG PGPPG  GP+GP G+         PGLPG DG PG+  +G PG PG +G
Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 868 LKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGK---DGDHGK 923
            +G PG  G  G  G  G PG  G PG PG +G P ++  G PG PG PG+    G+HG+
Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 924 PGIQGQPGPPG 934
            G+ G PG PG
Sbjct: 770 IGLPGLPGLPG 780



 Score =  369 bits (948), Expect = e-102
 Identities = 231/555 (41%), Positives = 272/555 (49%), Gaps = 89/555 (16%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPG---------------------QDGKPGYQGIAG 485
            PPG PG  G +G PG+PG  G  G PG                       G+PG +G AG
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 486  TPG------VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKG 539
             PG      VPG PG++G +GLPG  G PG  GD G  G PG PGL G+PGS G MG  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024

Query: 540  DKGS------------PGFYGKKGAKGEKGNAGF-----PGLPGPAGEPG------RHGK 576
             KG             PG  G  G +G+KG  G+     PG PGP G+PG      + G+
Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 577  DGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM 636
             G  G PG  G AG  GAPG  G+ G PG PG  G+ G  G KG +GPPG +G  G PG 
Sbjct: 1085 MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGF 1144

Query: 637  PGL---MGSNGSPGQPGTPGSKGSKGEPGI-QGMPGASGLKGEPGATGSPGEPGYMGLPG 692
            PG    MG  G  G+ G PG  G KGE G+ +  PG  G  G  GA G  G PG+ GLPG
Sbjct: 1145 PGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPG 1204

Query: 693  IQGKKGDKGNQGEKGIQGQKGENGRQG--IPGQQGIQGHHGAKGERGEKGEPGVRGA--I 748
             +G  GD G +G  GI+G  G  G  G  IPGQ G +G  G++G  G  G PG  G+  I
Sbjct: 1205 RKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI 1264

Query: 749  GSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVL 808
            G KG+ G  G  GP GP G  GD GP G  G  G PG                   LP  
Sbjct: 1265 GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG-------------------LPGP 1305

Query: 809  LQSGRIRNCDHCLSQHGSPGIPG---PPGPIGPEGPRGLPGLPGR------DGVPGLVGV 859
                  +       + G+PG  G   PPGPIGP+GP G+ G PG        G PG  G 
Sbjct: 1306 RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT 1365

Query: 860  PGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKD 918
            PG PG++G  G PG  G  G  G  G PG+ G PG PGP G  G   +G  G+PG  G D
Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG--NKGSKGEPGPAGSD 1423

Query: 919  GDHGKPGIQGQPGPP 933
            G  G  G +G  G P
Sbjct: 1424 GLPGLKGKRGDSGSP 1438



 Score =  367 bits (941), Expect = e-101
 Identities = 233/536 (43%), Positives = 268/536 (50%), Gaps = 55/536 (10%)

Query: 439  STPAPCIC-PPGKPGLQGPKGDPGLPGNPGY---PGQPGQDGKPGYQGIAGTPGVPGSPG 494
            STP P    PPG PG  GP+G PG+PG+ G    PG PG DG+PG  GI    G PG PG
Sbjct: 651  STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI----GFPGPPG 706

Query: 495  IQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGE--MGAKGDKGSPGFYGKKGA 552
             +G +G PG KG  G  G  G+ GLPG PGL   PG+KGE  +   G  G+PGF G++G 
Sbjct: 707  PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGN 763

Query: 553  KGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ--DGTRGEPGIPGFP 610
             GE G  G PGLPG  G PG  G DG  G PG  G  G  G PG+  +G RG  G+PG  
Sbjct: 764  SGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823

Query: 611  GNRGLMGQKGEIGP--------------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG 656
            G +G  G++G+ GP              PG+ G  G PG  G MG  G  G PG PG  G
Sbjct: 824  GLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG 883

Query: 657  SKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENG 716
              GE G+ GM G  G  G PG  G+PG PG  G PGI G KG +G  G KG QG KG  G
Sbjct: 884  PPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPG 943

Query: 717  RQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776
               I    G +G  G KG  G  GE G RG  G  G  G+ GL GPAGP G  GD G  G
Sbjct: 944  PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTG 1003

Query: 777  PPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI 836
             PG  G  G   S   +    +   R  L    ++GR             PG+PG  G  
Sbjct: 1004 NPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR-------------PGLPGIHGLQ 1050

Query: 837  GPEGPRGL-----PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQG 890
            G +G  G      PG PG  G PGL G  G+ G  G  G PG  G  G +G  G PG  G
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 891  PPGPPGPEGPPGISKE----GPPG---DPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
             PG PGP G  G        GPPG    PGLPG  G  G  GI+G  G  GI  P+
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA 1166



 Score =  358 bits (920), Expect = 1e-98
 Identities = 244/621 (39%), Positives = 293/621 (47%), Gaps = 131/621 (21%)

Query: 432 NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQD--GKPGYQGIAGTPGV 489
           +GP  V  +P        +PGL+G  G PGL G+ G  G+PG+D  G PG  G AG+PG+
Sbjct: 374 SGPPGVPGSPGS-----SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGL 428

Query: 490 PGSPGIQGA-------------RGLPGYKGEPGR---DGDKGDRGL--------PGFPGL 525
           PGSPG  G               GLPGY G PG    DG KG+ GL        PG PGL
Sbjct: 429 PGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGL 488

Query: 526 HGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGK-------DG 578
            G+PG  G  G  G +G+ G  G  G+ G  G  GFPG PG  G+PG  G+       +G
Sbjct: 489 PGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG 548

Query: 579 LMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRG---LMGQKGEIGPPGQQGKKGAPG 635
            +G PG  G  G PG  G DG  G PG+ G PG +G   L G+KG+ GPPG  G  G+PG
Sbjct: 549 QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPG 608

Query: 636 M--------------PGLMGSNGSPGQPGTPGSKGSKGE-------------------PG 662
                          PGL G+ G PG PG PG  G +GE                   PG
Sbjct: 609 PAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668

Query: 663 IQG---MPGASGLKGEPGATGSPGEPGY--MGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
            QG   +PG+ G  G+PG  G  GEPG   +G PG  G KGD+G  G KG  G  G+ G 
Sbjct: 669 PQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGE 728

Query: 718 QGIPGQQGIQGHHGA-----------------KGERGEKGEPGVRGAIGSKGESGVDGLM 760
            G+PG+ G+ G  G                  +G  GE GE G+ G  G  G  G +GL 
Sbjct: 729 PGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLD 788

Query: 761 GPAGPKGQPGDPGPQGPPG--LDGKPGREFSEQFIRQVCTDVIRAQLPVLL----QSGRI 814
           GP G  GQPG PG QGPPG  ++G  G +                 LP L     Q GR 
Sbjct: 789 GPRGDPGQPGPPGEQGPPGRCIEGPRGAQ----------------GLPGLNGLKGQQGRR 832

Query: 815 RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                     G PGIPG     G  G  G PG+PG  G  G +G  G PG  G+ G PG 
Sbjct: 833 GKT----GPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 875 NGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           +G  G  GF  PG  GPPGPPG  G PG       G PG+PG  G  G PG +G+ G  G
Sbjct: 888 DGVIGMMGF--PGAIGPPGPPGNPGTPG-----QRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 935 ICDPSLCFSVIA-RRDPFRKG 954
              PS    VI  + +P  KG
Sbjct: 941 NPGPSEISHVIGDKGEPGLKG 961



 Score =  346 bits (887), Expect = 7e-95
 Identities = 235/565 (41%), Positives = 274/565 (48%), Gaps = 93/565 (16%)

Query: 444 CICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG---SPGIQGARG 500
           C C  G  G +G KG PG PG+PG  G  G +G PG QG  G PG+PG   S G++G  G
Sbjct: 39  CFCD-GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISG 97

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS------PGFYGKKGAKG 554
           LPG+ G PG  G  G+ G  G  G+ G  GSKGE G  G  G+      PG  G KG KG
Sbjct: 98  LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKG 157

Query: 555 -----------EKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
                       KG+ G PG PGP G PG  G  G +G PG  G  G PGA G  G +G 
Sbjct: 158 APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGH 217

Query: 604 PG--IPGFPGNRGLMGQKGEIGPPG-----------QQGKKGAPGMPGLMGSNGSPGQPG 650
            G  + G  G RG+ G  G  GPPG           +   KG  G  G MG  G PG  G
Sbjct: 218 MGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277

Query: 651 TPG-----SKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGE 705
            PG      KG+ G+PG+QG PG  G+ G PG+ G  G  G+ GL G  G KG KG+ G 
Sbjct: 278 LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 706 KGIQG---------QKGENGRQGIPGQQGIQGHHGAKGERGEKG-----EPGVRGAIGSK 751
            G +G         +KG+ G  G PG +G +G  G  G  G  G      PG+RGA G  
Sbjct: 338 PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397

Query: 752 GESGVDGLMGPAG--PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLL 809
           G  G  G  G  G    G PG PG  G PGL G PG       I      V R   P   
Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI------VFRKGPP--- 448

Query: 810 QSGRIRNCDHCLSQH-GSPGIPGPPGPIGPEG--------PRGLPGLPGRDGVPGLVGVP 860
                   DH L  + GSPGIPG  GP G  G          G PGLPG  G+ G+ G+P
Sbjct: 449 -------GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501

Query: 861 GRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGPPGPPGPEG----PPGISKEGPPGDPGLP 915
           GR G  GLKG PG  G  G  GF G+PG QG PG  G +G    P G  + G PGDPGL 
Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG--QVGVPGDPGLR 559

Query: 916 GK------DGDHGKPGIQGQPGPPG 934
           G+      DG  G PG++G PGP G
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKG 584



 Score =  308 bits (788), Expect = 2e-83
 Identities = 192/433 (44%), Positives = 226/433 (52%), Gaps = 49/433 (11%)

Query: 551 GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
           GAKGEKG  GFPG PG  G+ G  G +GL G  G KG  G PG  G  G RG  G+PGF 
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 611 GNRGLMGQKGEIGP------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG-------- 656
           G+ GL G  G  GP      PG  G KG  G PGL G+ G PG PG  G KG        
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 657 ------SKGEPGIQGMPGASGLKGE---PGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707
                 +KG+PG+ G PG  GL G    PG  G PG PG+ G PG  G +G KG+ GE+ 
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 708 IQGQKGENGRQGIPGQQGIQGH-----HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGP 762
           I G KGE G +G+ G  G  G       G       KGE G +GA+G  G  G  GL G 
Sbjct: 223 I-GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 763 A--GPKGQPGDPGPQGPPGLDGKPGREFSE------QFIRQVCTDVIRAQLPVLLQSGRI 814
           +    KG PGDPG QG PG DG PG   SE       F   +  D I+ Q   +   G  
Sbjct: 282 SYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR 341

Query: 815 RNCDH--CLSQHGSPGIPGPPGP---IGPEGPRGLPGLPGRDGV--PGLVGVPGRPGVRG 867
              ++     + G  G PGPPGP    GP+GP G PG+PG  G   PGL G PG PG++G
Sbjct: 342 GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKG 401

Query: 868 LKGLPGRNGE--KGSQGF-GYPGEQGPPGPPGPEGPPG--ISKEGPPGDPGLPGKDGDHG 922
            KG  GR G+   G+ G  G  G  G PG PGP GPPG  + ++GPPGD GLPG  G  G
Sbjct: 402 SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461

Query: 923 KPGIQGQPGPPGI 935
            PG+ G  G PG+
Sbjct: 462 IPGVDGPKGEPGL 474



 Score =  286 bits (731), Expect = 8e-77
 Identities = 172/387 (44%), Positives = 193/387 (49%), Gaps = 45/387 (11%)

Query: 450  KPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPG 509
            +PG  GP GDPGLPG+ G  G+ GQ G PG+ G AG  G PGSPG  G  G PG  G+ G
Sbjct: 1063 RPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122

Query: 510  RDGDKGDRGLPGF---PGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
              G KG  G PG    PGL G PGS G MG +GD+G  G  G  G KGE G    P  PG
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP--PG 1180

Query: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMG-----QKGE 621
            P G PG  G  G  G+PGF G  G  GA G  G RG  GI GFPG  GL G     Q G 
Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGN 1240

Query: 622  IGPPGQQGKKGAPGMPGLMGSN--------------------------GSPGQ---PGTP 652
             GPPG +G  GAPG PG  GS+                          G PG+   PGTP
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300

Query: 653  GSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN------QGEK 706
            G  G +G+PG QG PG  G KG PG  GS G PG +G  G  G +GD G        G  
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360

Query: 707  GIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPK 766
            G  G  GE G QG PG  G  G+ G  G RG+ G+ G  G  G  GE G  G  G  GP 
Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPA 1420

Query: 767  GQPGDPGPQGPPGLDGKPGREFSEQFI 793
            G  G PG +G  G  G P    +  F+
Sbjct: 1421 GSDGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  270 bits (691), Expect = 4e-72
 Identities = 181/458 (39%), Positives = 211/458 (46%), Gaps = 91/458 (19%)

Query: 536 GAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP 595
           GAKG+KG  GF G  G+ G+KG  G  GLPGP G  G  G  GL GS G +G +G PG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSK 655
           G       PG+PG PGN G  G  G  G  G +G++G PG+PG +G  G PG  G  G K
Sbjct: 103 GS------PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 656 GS-----------KGEPGIQGMPGASGLKGEPG---ATGSPGEPGYMGLPGIQGKKGDKG 701
           G+           KG+PG+ G PG  GL G PG     G PG PG+ G PG  G +G KG
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 702 NQGEKGIQGQKGENGRQGIPGQQGIQGH-----HGAKGERGEKGEPGVRGAIGSKGESGV 756
           + GE+ I G KGE G +G+ G  G  G       G       KGE G +GA+G  G  G 
Sbjct: 217 HMGERVI-GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGP 275

Query: 757 DGLMGPA--GPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
            GL G +    KG PGDPG QG PG D                                 
Sbjct: 276 SGLPGESYGSEKGAPGDPGLQGKPGKD--------------------------------- 302

Query: 815 RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                        G+PG PG  G +G RG PGL G DG+ G  G  G PG RG       
Sbjct: 303 -------------GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349

Query: 875 NGEKGSQGFGYP----GEQGPPGPPGPEGPPGI------SKEGPPGDPGLPGKDGDHGKP 924
             EKG +G   P    G +GP GP GP G PG          G PG PGL G  G+ G+P
Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409

Query: 925 G--IQGQPGPPGIC-DPSLCFSVIARRDP----FRKGP 955
           G    G PG PG    P L  S      P    FRKGP
Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447



 Score =  253 bits (645), Expect = 8e-67
 Identities = 148/356 (41%), Positives = 175/356 (49%), Gaps = 65/356 (18%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGT------------PGVPGSPG 494
            PPG  G  GP+G PG PG+PG PG+PG  G  G++GI G             PG PGSPG
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 495  IQGARG----------------------LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSK 532
              G RG                       PG +G PG  G KGDRG PGFPGL G  G+ 
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 533  GEMGAKGDKGSPGFYG-----------KKGAKGEKGNAGFPGLPGPAGEPGRH-----GK 576
            G+ G +G  G  GF G           + G +G  G+ G PG PGP G PG H     G 
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269

Query: 577  DGLMGSPGFKG------------EAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKG---E 621
             G MG PG KG              G+PG PG  G RG+PG  GFPG +G  G  G    
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 622  IGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGS 681
            IGPPG  G KG PG+ G  G+      PG+PG  G+ GEPG+QG PG  G  G  G  G 
Sbjct: 1330 IGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389

Query: 682  PGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             G+PG  G PG  G  G+KGN+G KG  G  G +G  G+ G++G  G       RG
Sbjct: 1390 RGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  207 bits (528), Expect = 3e-53
 Identities = 128/291 (43%), Positives = 145/291 (49%), Gaps = 45/291 (15%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            IPG  GE      + G   AP   P G PG QG KGD G PG PG PG+ G  G  G +G
Sbjct: 1162 IPGPAGE----KGETGLLRAPP-GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG 1216

Query: 483  IAGTPGVPGSPGIQGA--------RGLPGYKGEPGRDGD-----------KGDRGLPGFP 523
              G  G PG PG+ GA        RG PG +G PG  G            KGD+G  G P
Sbjct: 1217 PTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP 1276

Query: 524  GLHGMPGSKGEMGAKG------------DKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEP 571
            G  G PG+ G+MG  G             +G PGF G  G KGEKGN GF G  GP G  
Sbjct: 1277 GPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPI 1336

Query: 572  GRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKK 631
            G  G  G+ G PG       PG+PG  GT GEPG+ G PG  G  G  G  GP G+ GK 
Sbjct: 1337 GPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD 1396

Query: 632  GAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
            G P         G+PG  G  G+KGSKGEPG  G  G  GLKG+ G +GSP
Sbjct: 1397 GKP---------GTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score =  173 bits (438), Expect = 8e-43
 Identities = 114/299 (38%), Positives = 131/299 (43%), Gaps = 39/299 (13%)

Query: 658 KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
           KG+    G  G  G KG PG  GSPG+ G+ G  G+ G +G KG  G  G+ G KG  G 
Sbjct: 36  KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGI 95

Query: 718 QGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGP 777
            G+PG  G  G  G  G  G  G  GV G  GSKGE G  GL G  G    PG PG  G 
Sbjct: 96  SGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG---YPGIPGAAGL 152

Query: 778 PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIG 837
            G  G P +E   +                             L   G PG+PG PGP G
Sbjct: 153 KGQKGAPAKEEDIE-----------------------------LDAKGDPGLPGAPGPQG 183

Query: 838 PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRN--GEKGSQGFGYPGEQGPPGPP 895
             GP G PG  G  G PG  G PG  G RG KG  G    G KG +G      +G  GPP
Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGV-----KGLTGPP 238

Query: 896 GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKG 954
           GP G   ++  GP     L G+ GD G  G  G PGP G+   S      A  DP  +G
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297



 Score =  141 bits (356), Expect = 3e-33
 Identities = 88/200 (44%), Positives = 97/200 (48%), Gaps = 15/200 (7%)

Query: 424  PGFNGECLNG-PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            PG  G  + G   D GS   P   P G PG  G  G PG  G PG PG PG  G PG+QG
Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPG--PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRG------LPGFPGLHGMPGSKGEMG 536
              G  G  G+PG  G+ G PG  G  G  G +GD G      LPG PG  G PG  G  G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 537  AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPG 596
              G  G PG  G  G +G+ G  G PG PGPAGE G        GS G  G AGS G PG
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN------KGSKGEPGPAGSDGLPG 1427

Query: 597  QDGTRGEPGIPGFPGNRGLM 616
              G RG+ G P     RG +
Sbjct: 1428 LKGKRGDSGSPATWTTRGFV 1447


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  392 bits (1008), Expect = e-109
 Identities = 229/539 (42%), Positives = 275/539 (51%), Gaps = 68/539 (12%)

Query: 448  PGKPGLQGPKGDPG--LPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYK 505
            PGKPGL G KG+P   +PG PG PG PG+ G  G  G  G PG+PG PG  G  GL G +
Sbjct: 732  PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791

Query: 506  GEPGR--------------DGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKG--------- 542
            G+PG+              +G +G +GLPG  GL G  G +G+ G KGD G         
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851

Query: 543  -----SPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ 597
                 SPG  G +G  G  G  G+PG PG  G PG  G  G+MG PG  G  G PG PG 
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 598  DGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQ---------GKKGAPGMPGLMGSNGSPGQ 648
             G RG PGIPG  G RG  G KGE G  G           G KG PG+ G  G+ G  G 
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 649  PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
             G PG  G KG  G+ G  G  G +G+ G+TG+PGEPG  G+PG  G  G  G++G++G 
Sbjct: 972  RGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031

Query: 709  QGQKGENGRQGIPGQQGIQGHHG--------AKGERGEKGEPGVRGAIGSKGESGVDGLM 760
             G  G  GR G+PG  G+QG  G          G  G  G+PG+ G +G KGE G  G  
Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPP 1091

Query: 761  GPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHC 820
            G  GP G  G PG  G PGL GKPG             D+    +  LL    IR     
Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPH----------GDLGFKGIKGLLGPPGIR----- 1136

Query: 821  LSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVG-VPGRPGVRGLKGLPGRNGEKG 879
                G PG PG PGP+G  G +G  G+PG  G  G  G +   PG RG  G  G  G++G
Sbjct: 1137 -GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 880  SQGF-GYPGEQGPPGPPGPEGPPGISK-EGPPGDPG--LPGKDGDHGKPGIQGQPGPPG 934
            + GF G PG +G  G  GP GP GI    GPPG PG  +PG+ G+ G PG +G PG PG
Sbjct: 1196 APGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254



 Score =  391 bits (1005), Expect = e-108
 Identities = 248/575 (43%), Positives = 291/575 (50%), Gaps = 86/575 (14%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK------ 477
            PG  G  L+     G T +P I  PG  G  GP G  G PGNPG  G PG+DG       
Sbjct: 841  PGIPG--LDRSGFPGETGSPGI--PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 478  PGYQGIAGTPGVPGSPGIQGARGLPGYKGE---PGRDGDKGDRGLPGFPGLHGMPGSKGE 534
            PG  G  G PG PG+PG +G+ G+PG KG+   PG  G++GD+G PG   +  + G KGE
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 535  MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHG---------KDGLMGSPGF 585
             G KG  G+PG  G +G  G  G  G  GLPGPAG PG  G         + GL G PG 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 586  KGEAGSPGAPGQDGTRGEPGI---PGFPGNRGLMGQKGEIG-----PPGQQGKKGAPGMP 637
             G  G PG+ G+ GT G PG    PG PG  GL G KGE G      PG  G  G PG+P
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 638  GLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGL---PGIQ 694
            G MG  G  GQPG PG  G  G  G  G PG+ GL G+PG  G  G  G  GL   PGI+
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 695  GKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGA-KGERGEKGEPGVRGAIGSKGE 753
            G  G  G  G  G  G +G+ GR GIPG  G +G  G  +   G +G PG +GA   KG+
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA---KGD 1193

Query: 754  SGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGR 813
             G  G  G  G KG  GD GP+GP G++G PG                   LP  +  G+
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP----------------GLPGAIIPGQ 1237

Query: 814  IRNCDHCLSQHGSPGIPGPPGP--------------IGPEGPRGLPGL------PGRDGV 853
              N     S+ GSPG PGPPGP              +G  GP+G PG       PGR G 
Sbjct: 1238 TGNRGPPGSR-GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA 1296

Query: 854  PGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPG----------I 903
            PG  G+PG  G  G +G PG  GEKG+ GF   G  GPPGP GP+GPPG          I
Sbjct: 1297 PGTPGLPGPRGDPGFQGFPGVKGEKGNPGF--LGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 904  SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            S  G PG PG PG+ G  G+PG  G PG  G C P
Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  378 bits (971), Expect = e-104
 Identities = 247/613 (40%), Positives = 294/613 (47%), Gaps = 111/613 (18%)

Query: 423  IPGFNGEC-LNG-PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQP-GQDGKPG 479
            IPG  G   L G P   G+T  P     G PG  G +GDPGL G  G   QP GQ G PG
Sbjct: 500  IPGRQGAAGLKGSPGSPGNTGLP-----GFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG 554

Query: 480  YQGIAGTPG---VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536
              G+ G PG   + G PG  G +GLPG KGE    G+KGD+G PG PG  G PG  G  G
Sbjct: 555  DPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614

Query: 537  AKG--DKGSPGFYGKKGAKGEKGNAG-------------FPGLPGPAGEPGRHGKDGLMG 581
              G   +G PG  G +G  G  G  G              PG PGP G PG  G  G  G
Sbjct: 615  PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG 674

Query: 582  SPGFKGEAGSPGAPGQDGTRGEPGI-----PGFPGNRGLMGQKGEIGPPGQQGKKGAPGM 636
             PG  G+ G PG PG DG  G PGI     PG  G++G  G KG +G PG+ G+ G PG 
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734

Query: 637  PGLMGSNGSP--------GQPGTPGSKGSKGE---------PGIQGMPGASGLKGEPGAT 679
            PGL G+ G P        G PG PG +G+ GE         PG+ G PG  GL G  G  
Sbjct: 735  PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 680  GSPGEPGYMGLPG--IQGKKGDKGNQGEKGIQGQKGENG--------------RQGIPGQ 723
            G PG PG  G PG  I+G +G +G  G  G++GQ+G  G              R G PG+
Sbjct: 795  GQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGE 854

Query: 724  QG---IQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMG------PAGPKGQPGDPGP 774
             G   I GH G  G  G++G PG  G +G  GE GV G+MG      P GP G PG PG 
Sbjct: 855  TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914

Query: 775  QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPG 834
            +G PG+ G  G         Q  T   + +       G      H +   G PG+ G  G
Sbjct: 915  RGSPGIPGVKG---------QRGTPGAKGEQGDKGNPGP-SEISHVIGDKGEPGLKGFAG 964

Query: 835  PIGPEGPRGLPGLPGRDGVPGL---------------VGVPGRPGVRGLKGLPGRNGEKG 879
              G +G RG+PG+PG  G+ GL                G PG PG+RG+ G  G  G  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024

Query: 880  SQG----FGYPGEQGPPGPPG------PEGPPGIS---KEGPPGDPGLPGKDGDHGKPGI 926
            S+G     G+PG  G PG PG       +G PG S   + GPPG  G PG  GD GK G 
Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 927  QGQPGPPGICDPS 939
             GQPGPPG   P+
Sbjct: 1085 MGQPGPPGHLGPA 1097



 Score =  375 bits (963), Expect = e-103
 Identities = 234/551 (42%), Positives = 281/551 (50%), Gaps = 70/551 (12%)

Query: 447 PPGKPG-----LQGP------KGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGI 495
           PPG PG     L GP      KG+ G  G  G PG PG  G PG +      G PG PG+
Sbjct: 237 PPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-ESYGSEKGAPGDPGL 295

Query: 496 QGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGA---------------KGD 540
           QG  G  G  G PG +G KG+RG PG  G  G+ G KG++G                KGD
Sbjct: 296 QGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGD 355

Query: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600
           +G+PG  G +GA+G +G +G PG+PG  G   R G  G  G PG KG  G  G PG+D  
Sbjct: 356 EGTPGPPGPRGARGPQGPSGPPGVPGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAM 414

Query: 601 RGEPGIPGFPGNRGLMGQKGEIGPPGQ-QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKG 659
            G PG PG  G+ GL G  G  GPPG    +KG PG  GL G  GSPG PG  G KG  G
Sbjct: 415 -GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPG 473

Query: 660 -----------EPGIQGMPGASGLKGEPGATG------SPGEPGYMGLPGIQGKKGDKGN 702
                       PG+ G+PG  G+KG PG  G      SPG PG  GLPG  G  G    
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGA--- 530

Query: 703 QGEKGIQGQKGEN----GRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDG 758
           QG+ G++G+KGE     G+ G+PG  G++G  G KG  G  G PGV+G  G KGE  + G
Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590

Query: 759 LMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCD 818
             G  GP G PG PG  GP G  G PG     +   Q    V  A  P   ++G      
Sbjct: 591 EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP-GEAGPRGELS 649

Query: 819 HCLSQHGSPGIPGPPGPIGPEGPRGL---------PGLPGRDGVPGL--VGVPGRPGVRG 867
                 G PG PGPPG  GP+GP G+         PGLPG DG PG+  +G PG PG +G
Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 868 LKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGK---DGDHGK 923
            +G PG  G  G  G  G PG  G PG PG +G P ++  G PG PG PG+    G+HG+
Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 924 PGIQGQPGPPG 934
            G+ G PG PG
Sbjct: 770 IGLPGLPGLPG 780



 Score =  369 bits (948), Expect = e-102
 Identities = 231/555 (41%), Positives = 272/555 (49%), Gaps = 89/555 (16%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPG---------------------QDGKPGYQGIAG 485
            PPG PG  G +G PG+PG  G  G PG                       G+PG +G AG
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 486  TPG------VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKG 539
             PG      VPG PG++G +GLPG  G PG  GD G  G PG PGL G+PGS G MG  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024

Query: 540  DKGS------------PGFYGKKGAKGEKGNAGF-----PGLPGPAGEPG------RHGK 576
             KG             PG  G  G +G+KG  G+     PG PGP G+PG      + G+
Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 577  DGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM 636
             G  G PG  G AG  GAPG  G+ G PG PG  G+ G  G KG +GPPG +G  G PG 
Sbjct: 1085 MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGF 1144

Query: 637  PGL---MGSNGSPGQPGTPGSKGSKGEPGI-QGMPGASGLKGEPGATGSPGEPGYMGLPG 692
            PG    MG  G  G+ G PG  G KGE G+ +  PG  G  G  GA G  G PG+ GLPG
Sbjct: 1145 PGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPG 1204

Query: 693  IQGKKGDKGNQGEKGIQGQKGENGRQG--IPGQQGIQGHHGAKGERGEKGEPGVRGA--I 748
             +G  GD G +G  GI+G  G  G  G  IPGQ G +G  G++G  G  G PG  G+  I
Sbjct: 1205 RKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI 1264

Query: 749  GSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVL 808
            G KG+ G  G  GP GP G  GD GP G  G  G PG                   LP  
Sbjct: 1265 GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG-------------------LPGP 1305

Query: 809  LQSGRIRNCDHCLSQHGSPGIPG---PPGPIGPEGPRGLPGLPGR------DGVPGLVGV 859
                  +       + G+PG  G   PPGPIGP+GP G+ G PG        G PG  G 
Sbjct: 1306 RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT 1365

Query: 860  PGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKD 918
            PG PG++G  G PG  G  G  G  G PG+ G PG PGP G  G   +G  G+PG  G D
Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG--NKGSKGEPGPAGSD 1423

Query: 919  GDHGKPGIQGQPGPP 933
            G  G  G +G  G P
Sbjct: 1424 GLPGLKGKRGDSGSP 1438



 Score =  367 bits (941), Expect = e-101
 Identities = 233/536 (43%), Positives = 268/536 (50%), Gaps = 55/536 (10%)

Query: 439  STPAPCIC-PPGKPGLQGPKGDPGLPGNPGY---PGQPGQDGKPGYQGIAGTPGVPGSPG 494
            STP P    PPG PG  GP+G PG+PG+ G    PG PG DG+PG  GI    G PG PG
Sbjct: 651  STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI----GFPGPPG 706

Query: 495  IQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGE--MGAKGDKGSPGFYGKKGA 552
             +G +G PG KG  G  G  G+ GLPG PGL   PG+KGE  +   G  G+PGF G++G 
Sbjct: 707  PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGN 763

Query: 553  KGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ--DGTRGEPGIPGFP 610
             GE G  G PGLPG  G PG  G DG  G PG  G  G  G PG+  +G RG  G+PG  
Sbjct: 764  SGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823

Query: 611  GNRGLMGQKGEIGP--------------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG 656
            G +G  G++G+ GP              PG+ G  G PG  G MG  G  G PG PG  G
Sbjct: 824  GLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG 883

Query: 657  SKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENG 716
              GE G+ GM G  G  G PG  G+PG PG  G PGI G KG +G  G KG QG KG  G
Sbjct: 884  PPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPG 943

Query: 717  RQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776
               I    G +G  G KG  G  GE G RG  G  G  G+ GL GPAGP G  GD G  G
Sbjct: 944  PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTG 1003

Query: 777  PPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI 836
             PG  G  G   S   +    +   R  L    ++GR             PG+PG  G  
Sbjct: 1004 NPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR-------------PGLPGIHGLQ 1050

Query: 837  GPEGPRGL-----PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQG 890
            G +G  G      PG PG  G PGL G  G+ G  G  G PG  G  G +G  G PG  G
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 891  PPGPPGPEGPPGISKE----GPPG---DPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
             PG PGP G  G        GPPG    PGLPG  G  G  GI+G  G  GI  P+
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA 1166



 Score =  358 bits (920), Expect = 1e-98
 Identities = 244/621 (39%), Positives = 293/621 (47%), Gaps = 131/621 (21%)

Query: 432 NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQD--GKPGYQGIAGTPGV 489
           +GP  V  +P        +PGL+G  G PGL G+ G  G+PG+D  G PG  G AG+PG+
Sbjct: 374 SGPPGVPGSPGS-----SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGL 428

Query: 490 PGSPGIQGA-------------RGLPGYKGEPGR---DGDKGDRGL--------PGFPGL 525
           PGSPG  G               GLPGY G PG    DG KG+ GL        PG PGL
Sbjct: 429 PGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGL 488

Query: 526 HGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGK-------DG 578
            G+PG  G  G  G +G+ G  G  G+ G  G  GFPG PG  G+PG  G+       +G
Sbjct: 489 PGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG 548

Query: 579 LMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRG---LMGQKGEIGPPGQQGKKGAPG 635
            +G PG  G  G PG  G DG  G PG+ G PG +G   L G+KG+ GPPG  G  G+PG
Sbjct: 549 QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPG 608

Query: 636 M--------------PGLMGSNGSPGQPGTPGSKGSKGE-------------------PG 662
                          PGL G+ G PG PG PG  G +GE                   PG
Sbjct: 609 PAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668

Query: 663 IQG---MPGASGLKGEPGATGSPGEPGY--MGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
            QG   +PG+ G  G+PG  G  GEPG   +G PG  G KGD+G  G KG  G  G+ G 
Sbjct: 669 PQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGE 728

Query: 718 QGIPGQQGIQGHHGA-----------------KGERGEKGEPGVRGAIGSKGESGVDGLM 760
            G+PG+ G+ G  G                  +G  GE GE G+ G  G  G  G +GL 
Sbjct: 729 PGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLD 788

Query: 761 GPAGPKGQPGDPGPQGPPG--LDGKPGREFSEQFIRQVCTDVIRAQLPVLL----QSGRI 814
           GP G  GQPG PG QGPPG  ++G  G +                 LP L     Q GR 
Sbjct: 789 GPRGDPGQPGPPGEQGPPGRCIEGPRGAQ----------------GLPGLNGLKGQQGRR 832

Query: 815 RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                     G PGIPG     G  G  G PG+PG  G  G +G  G PG  G+ G PG 
Sbjct: 833 GKT----GPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 875 NGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           +G  G  GF  PG  GPPGPPG  G PG       G PG+PG  G  G PG +G+ G  G
Sbjct: 888 DGVIGMMGF--PGAIGPPGPPGNPGTPG-----QRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 935 ICDPSLCFSVIA-RRDPFRKG 954
              PS    VI  + +P  KG
Sbjct: 941 NPGPSEISHVIGDKGEPGLKG 961



 Score =  346 bits (887), Expect = 7e-95
 Identities = 235/565 (41%), Positives = 274/565 (48%), Gaps = 93/565 (16%)

Query: 444 CICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG---SPGIQGARG 500
           C C  G  G +G KG PG PG+PG  G  G +G PG QG  G PG+PG   S G++G  G
Sbjct: 39  CFCD-GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISG 97

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS------PGFYGKKGAKG 554
           LPG+ G PG  G  G+ G  G  G+ G  GSKGE G  G  G+      PG  G KG KG
Sbjct: 98  LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKG 157

Query: 555 -----------EKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
                       KG+ G PG PGP G PG  G  G +G PG  G  G PGA G  G +G 
Sbjct: 158 APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGH 217

Query: 604 PG--IPGFPGNRGLMGQKGEIGPPG-----------QQGKKGAPGMPGLMGSNGSPGQPG 650
            G  + G  G RG+ G  G  GPPG           +   KG  G  G MG  G PG  G
Sbjct: 218 MGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277

Query: 651 TPG-----SKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGE 705
            PG      KG+ G+PG+QG PG  G+ G PG+ G  G  G+ GL G  G KG KG+ G 
Sbjct: 278 LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 706 KGIQG---------QKGENGRQGIPGQQGIQGHHGAKGERGEKG-----EPGVRGAIGSK 751
            G +G         +KG+ G  G PG +G +G  G  G  G  G      PG+RGA G  
Sbjct: 338 PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397

Query: 752 GESGVDGLMGPAG--PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLL 809
           G  G  G  G  G    G PG PG  G PGL G PG       I      V R   P   
Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI------VFRKGPP--- 448

Query: 810 QSGRIRNCDHCLSQH-GSPGIPGPPGPIGPEG--------PRGLPGLPGRDGVPGLVGVP 860
                   DH L  + GSPGIPG  GP G  G          G PGLPG  G+ G+ G+P
Sbjct: 449 -------GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501

Query: 861 GRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGPPGPPGPEG----PPGISKEGPPGDPGLP 915
           GR G  GLKG PG  G  G  GF G+PG QG PG  G +G    P G  + G PGDPGL 
Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG--QVGVPGDPGLR 559

Query: 916 GK------DGDHGKPGIQGQPGPPG 934
           G+      DG  G PG++G PGP G
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKG 584



 Score =  308 bits (788), Expect = 2e-83
 Identities = 192/433 (44%), Positives = 226/433 (52%), Gaps = 49/433 (11%)

Query: 551 GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
           GAKGEKG  GFPG PG  G+ G  G +GL G  G KG  G PG  G  G RG  G+PGF 
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 611 GNRGLMGQKGEIGP------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG-------- 656
           G+ GL G  G  GP      PG  G KG  G PGL G+ G PG PG  G KG        
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 657 ------SKGEPGIQGMPGASGLKGE---PGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707
                 +KG+PG+ G PG  GL G    PG  G PG PG+ G PG  G +G KG+ GE+ 
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 708 IQGQKGENGRQGIPGQQGIQGH-----HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGP 762
           I G KGE G +G+ G  G  G       G       KGE G +GA+G  G  G  GL G 
Sbjct: 223 I-GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 763 A--GPKGQPGDPGPQGPPGLDGKPGREFSE------QFIRQVCTDVIRAQLPVLLQSGRI 814
           +    KG PGDPG QG PG DG PG   SE       F   +  D I+ Q   +   G  
Sbjct: 282 SYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR 341

Query: 815 RNCDH--CLSQHGSPGIPGPPGP---IGPEGPRGLPGLPGRDGV--PGLVGVPGRPGVRG 867
              ++     + G  G PGPPGP    GP+GP G PG+PG  G   PGL G PG PG++G
Sbjct: 342 GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKG 401

Query: 868 LKGLPGRNGE--KGSQGF-GYPGEQGPPGPPGPEGPPG--ISKEGPPGDPGLPGKDGDHG 922
            KG  GR G+   G+ G  G  G  G PG PGP GPPG  + ++GPPGD GLPG  G  G
Sbjct: 402 SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461

Query: 923 KPGIQGQPGPPGI 935
            PG+ G  G PG+
Sbjct: 462 IPGVDGPKGEPGL 474



 Score =  286 bits (731), Expect = 8e-77
 Identities = 172/387 (44%), Positives = 193/387 (49%), Gaps = 45/387 (11%)

Query: 450  KPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPG 509
            +PG  GP GDPGLPG+ G  G+ GQ G PG+ G AG  G PGSPG  G  G PG  G+ G
Sbjct: 1063 RPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122

Query: 510  RDGDKGDRGLPGF---PGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
              G KG  G PG    PGL G PGS G MG +GD+G  G  G  G KGE G    P  PG
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP--PG 1180

Query: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMG-----QKGE 621
            P G PG  G  G  G+PGF G  G  GA G  G RG  GI GFPG  GL G     Q G 
Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGN 1240

Query: 622  IGPPGQQGKKGAPGMPGLMGSN--------------------------GSPGQ---PGTP 652
             GPPG +G  GAPG PG  GS+                          G PG+   PGTP
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300

Query: 653  GSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN------QGEK 706
            G  G +G+PG QG PG  G KG PG  GS G PG +G  G  G +GD G        G  
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360

Query: 707  GIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPK 766
            G  G  GE G QG PG  G  G+ G  G RG+ G+ G  G  G  GE G  G  G  GP 
Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPA 1420

Query: 767  GQPGDPGPQGPPGLDGKPGREFSEQFI 793
            G  G PG +G  G  G P    +  F+
Sbjct: 1421 GSDGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  270 bits (691), Expect = 4e-72
 Identities = 181/458 (39%), Positives = 211/458 (46%), Gaps = 91/458 (19%)

Query: 536 GAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP 595
           GAKG+KG  GF G  G+ G+KG  G  GLPGP G  G  G  GL GS G +G +G PG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSK 655
           G       PG+PG PGN G  G  G  G  G +G++G PG+PG +G  G PG  G  G K
Sbjct: 103 GS------PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 656 GS-----------KGEPGIQGMPGASGLKGEPG---ATGSPGEPGYMGLPGIQGKKGDKG 701
           G+           KG+PG+ G PG  GL G PG     G PG PG+ G PG  G +G KG
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 702 NQGEKGIQGQKGENGRQGIPGQQGIQGH-----HGAKGERGEKGEPGVRGAIGSKGESGV 756
           + GE+ I G KGE G +G+ G  G  G       G       KGE G +GA+G  G  G 
Sbjct: 217 HMGERVI-GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGP 275

Query: 757 DGLMGPA--GPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
            GL G +    KG PGDPG QG PG D                                 
Sbjct: 276 SGLPGESYGSEKGAPGDPGLQGKPGKD--------------------------------- 302

Query: 815 RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                        G+PG PG  G +G RG PGL G DG+ G  G  G PG RG       
Sbjct: 303 -------------GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349

Query: 875 NGEKGSQGFGYP----GEQGPPGPPGPEGPPGI------SKEGPPGDPGLPGKDGDHGKP 924
             EKG +G   P    G +GP GP GP G PG          G PG PGL G  G+ G+P
Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409

Query: 925 G--IQGQPGPPGIC-DPSLCFSVIARRDP----FRKGP 955
           G    G PG PG    P L  S      P    FRKGP
Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447



 Score =  253 bits (645), Expect = 8e-67
 Identities = 148/356 (41%), Positives = 175/356 (49%), Gaps = 65/356 (18%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGT------------PGVPGSPG 494
            PPG  G  GP+G PG PG+PG PG+PG  G  G++GI G             PG PGSPG
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 495  IQGARG----------------------LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSK 532
              G RG                       PG +G PG  G KGDRG PGFPGL G  G+ 
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 533  GEMGAKGDKGSPGFYG-----------KKGAKGEKGNAGFPGLPGPAGEPGRH-----GK 576
            G+ G +G  G  GF G           + G +G  G+ G PG PGP G PG H     G 
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269

Query: 577  DGLMGSPGFKG------------EAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKG---E 621
             G MG PG KG              G+PG PG  G RG+PG  GFPG +G  G  G    
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 622  IGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGS 681
            IGPPG  G KG PG+ G  G+      PG+PG  G+ GEPG+QG PG  G  G  G  G 
Sbjct: 1330 IGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389

Query: 682  PGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             G+PG  G PG  G  G+KGN+G KG  G  G +G  G+ G++G  G       RG
Sbjct: 1390 RGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  207 bits (528), Expect = 3e-53
 Identities = 128/291 (43%), Positives = 145/291 (49%), Gaps = 45/291 (15%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            IPG  GE      + G   AP   P G PG QG KGD G PG PG PG+ G  G  G +G
Sbjct: 1162 IPGPAGE----KGETGLLRAPP-GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG 1216

Query: 483  IAGTPGVPGSPGIQGA--------RGLPGYKGEPGRDGD-----------KGDRGLPGFP 523
              G  G PG PG+ GA        RG PG +G PG  G            KGD+G  G P
Sbjct: 1217 PTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP 1276

Query: 524  GLHGMPGSKGEMGAKG------------DKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEP 571
            G  G PG+ G+MG  G             +G PGF G  G KGEKGN GF G  GP G  
Sbjct: 1277 GPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPI 1336

Query: 572  GRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKK 631
            G  G  G+ G PG       PG+PG  GT GEPG+ G PG  G  G  G  GP G+ GK 
Sbjct: 1337 GPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD 1396

Query: 632  GAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
            G P         G+PG  G  G+KGSKGEPG  G  G  GLKG+ G +GSP
Sbjct: 1397 GKP---------GTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score =  173 bits (438), Expect = 8e-43
 Identities = 114/299 (38%), Positives = 131/299 (43%), Gaps = 39/299 (13%)

Query: 658 KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
           KG+    G  G  G KG PG  GSPG+ G+ G  G+ G +G KG  G  G+ G KG  G 
Sbjct: 36  KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGI 95

Query: 718 QGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGP 777
            G+PG  G  G  G  G  G  G  GV G  GSKGE G  GL G  G    PG PG  G 
Sbjct: 96  SGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG---YPGIPGAAGL 152

Query: 778 PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIG 837
            G  G P +E   +                             L   G PG+PG PGP G
Sbjct: 153 KGQKGAPAKEEDIE-----------------------------LDAKGDPGLPGAPGPQG 183

Query: 838 PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRN--GEKGSQGFGYPGEQGPPGPP 895
             GP G PG  G  G PG  G PG  G RG KG  G    G KG +G      +G  GPP
Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGV-----KGLTGPP 238

Query: 896 GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKG 954
           GP G   ++  GP     L G+ GD G  G  G PGP G+   S      A  DP  +G
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297



 Score =  141 bits (356), Expect = 3e-33
 Identities = 88/200 (44%), Positives = 97/200 (48%), Gaps = 15/200 (7%)

Query: 424  PGFNGECLNG-PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            PG  G  + G   D GS   P   P G PG  G  G PG  G PG PG PG  G PG+QG
Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPG--PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRG------LPGFPGLHGMPGSKGEMG 536
              G  G  G+PG  G+ G PG  G  G  G +GD G      LPG PG  G PG  G  G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 537  AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPG 596
              G  G PG  G  G +G+ G  G PG PGPAGE G        GS G  G AGS G PG
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN------KGSKGEPGPAGSDGLPG 1427

Query: 597  QDGTRGEPGIPGFPGNRGLM 616
              G RG+ G P     RG +
Sbjct: 1428 LKGKRGDSGSPATWTTRGFV 1447


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  392 bits (1008), Expect = e-109
 Identities = 229/539 (42%), Positives = 275/539 (51%), Gaps = 68/539 (12%)

Query: 448  PGKPGLQGPKGDPG--LPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYK 505
            PGKPGL G KG+P   +PG PG PG PG+ G  G  G  G PG+PG PG  G  GL G +
Sbjct: 732  PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR 791

Query: 506  GEPGR--------------DGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKG--------- 542
            G+PG+              +G +G +GLPG  GL G  G +G+ G KGD G         
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGF 851

Query: 543  -----SPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ 597
                 SPG  G +G  G  G  G+PG PG  G PG  G  G+MG PG  G  G PG PG 
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 598  DGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQ---------GKKGAPGMPGLMGSNGSPGQ 648
             G RG PGIPG  G RG  G KGE G  G           G KG PG+ G  G+ G  G 
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 649  PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
             G PG  G KG  G+ G  G  G +G+ G+TG+PGEPG  G+PG  G  G  G++G++G 
Sbjct: 972  RGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031

Query: 709  QGQKGENGRQGIPGQQGIQGHHG--------AKGERGEKGEPGVRGAIGSKGESGVDGLM 760
             G  G  GR G+PG  G+QG  G          G  G  G+PG+ G +G KGE G  G  
Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPP 1091

Query: 761  GPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHC 820
            G  GP G  G PG  G PGL GKPG             D+    +  LL    IR     
Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPH----------GDLGFKGIKGLLGPPGIR----- 1136

Query: 821  LSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVG-VPGRPGVRGLKGLPGRNGEKG 879
                G PG PG PGP+G  G +G  G+PG  G  G  G +   PG RG  G  G  G++G
Sbjct: 1137 -GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 880  SQGF-GYPGEQGPPGPPGPEGPPGISK-EGPPGDPG--LPGKDGDHGKPGIQGQPGPPG 934
            + GF G PG +G  G  GP GP GI    GPPG PG  +PG+ G+ G PG +G PG PG
Sbjct: 1196 APGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG 1254



 Score =  391 bits (1005), Expect = e-108
 Identities = 248/575 (43%), Positives = 291/575 (50%), Gaps = 86/575 (14%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK------ 477
            PG  G  L+     G T +P I  PG  G  GP G  G PGNPG  G PG+DG       
Sbjct: 841  PGIPG--LDRSGFPGETGSPGI--PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 478  PGYQGIAGTPGVPGSPGIQGARGLPGYKGE---PGRDGDKGDRGLPGFPGLHGMPGSKGE 534
            PG  G  G PG PG+PG +G+ G+PG KG+   PG  G++GD+G PG   +  + G KGE
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 535  MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHG---------KDGLMGSPGF 585
             G KG  G+PG  G +G  G  G  G  GLPGPAG PG  G         + GL G PG 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 586  KGEAGSPGAPGQDGTRGEPGI---PGFPGNRGLMGQKGEIG-----PPGQQGKKGAPGMP 637
             G  G PG+ G+ GT G PG    PG PG  GL G KGE G      PG  G  G PG+P
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 638  GLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGL---PGIQ 694
            G MG  G  GQPG PG  G  G  G  G PG+ GL G+PG  G  G  G  GL   PGI+
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 695  GKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGA-KGERGEKGEPGVRGAIGSKGE 753
            G  G  G  G  G  G +G+ GR GIPG  G +G  G  +   G +G PG +GA   KG+
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA---KGD 1193

Query: 754  SGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGR 813
             G  G  G  G KG  GD GP+GP G++G PG                   LP  +  G+
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP----------------GLPGAIIPGQ 1237

Query: 814  IRNCDHCLSQHGSPGIPGPPGP--------------IGPEGPRGLPGL------PGRDGV 853
              N     S+ GSPG PGPPGP              +G  GP+G PG       PGR G 
Sbjct: 1238 TGNRGPPGSR-GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGA 1296

Query: 854  PGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPG----------I 903
            PG  G+PG  G  G +G PG  GEKG+ GF   G  GPPGP GP+GPPG          I
Sbjct: 1297 PGTPGLPGPRGDPGFQGFPGVKGEKGNPGF--LGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 904  SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            S  G PG PG PG+ G  G+PG  G PG  G C P
Sbjct: 1355 SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  378 bits (971), Expect = e-104
 Identities = 247/613 (40%), Positives = 294/613 (47%), Gaps = 111/613 (18%)

Query: 423  IPGFNGEC-LNG-PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQP-GQDGKPG 479
            IPG  G   L G P   G+T  P     G PG  G +GDPGL G  G   QP GQ G PG
Sbjct: 500  IPGRQGAAGLKGSPGSPGNTGLP-----GFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG 554

Query: 480  YQGIAGTPG---VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536
              G+ G PG   + G PG  G +GLPG KGE    G+KGD+G PG PG  G PG  G  G
Sbjct: 555  DPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614

Query: 537  AKG--DKGSPGFYGKKGAKGEKGNAG-------------FPGLPGPAGEPGRHGKDGLMG 581
              G   +G PG  G +G  G  G  G              PG PGP G PG  G  G  G
Sbjct: 615  PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG 674

Query: 582  SPGFKGEAGSPGAPGQDGTRGEPGI-----PGFPGNRGLMGQKGEIGPPGQQGKKGAPGM 636
             PG  G+ G PG PG DG  G PGI     PG  G++G  G KG +G PG+ G+ G PG 
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734

Query: 637  PGLMGSNGSP--------GQPGTPGSKGSKGE---------PGIQGMPGASGLKGEPGAT 679
            PGL G+ G P        G PG PG +G+ GE         PG+ G PG  GL G  G  
Sbjct: 735  PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 680  GSPGEPGYMGLPG--IQGKKGDKGNQGEKGIQGQKGENG--------------RQGIPGQ 723
            G PG PG  G PG  I+G +G +G  G  G++GQ+G  G              R G PG+
Sbjct: 795  GQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGE 854

Query: 724  QG---IQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMG------PAGPKGQPGDPGP 774
             G   I GH G  G  G++G PG  G +G  GE GV G+MG      P GP G PG PG 
Sbjct: 855  TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914

Query: 775  QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPG 834
            +G PG+ G  G         Q  T   + +       G      H +   G PG+ G  G
Sbjct: 915  RGSPGIPGVKG---------QRGTPGAKGEQGDKGNPGP-SEISHVIGDKGEPGLKGFAG 964

Query: 835  PIGPEGPRGLPGLPGRDGVPGL---------------VGVPGRPGVRGLKGLPGRNGEKG 879
              G +G RG+PG+PG  G+ GL                G PG PG+RG+ G  G  G  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024

Query: 880  SQG----FGYPGEQGPPGPPG------PEGPPGIS---KEGPPGDPGLPGKDGDHGKPGI 926
            S+G     G+PG  G PG PG       +G PG S   + GPPG  G PG  GD GK G 
Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 927  QGQPGPPGICDPS 939
             GQPGPPG   P+
Sbjct: 1085 MGQPGPPGHLGPA 1097



 Score =  375 bits (963), Expect = e-103
 Identities = 234/551 (42%), Positives = 281/551 (50%), Gaps = 70/551 (12%)

Query: 447 PPGKPG-----LQGP------KGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGI 495
           PPG PG     L GP      KG+ G  G  G PG PG  G PG +      G PG PG+
Sbjct: 237 PPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-ESYGSEKGAPGDPGL 295

Query: 496 QGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGA---------------KGD 540
           QG  G  G  G PG +G KG+RG PG  G  G+ G KG++G                KGD
Sbjct: 296 QGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGD 355

Query: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600
           +G+PG  G +GA+G +G +G PG+PG  G   R G  G  G PG KG  G  G PG+D  
Sbjct: 356 EGTPGPPGPRGARGPQGPSGPPGVPGSPGS-SRPGLRGAPGWPGLKGSKGERGRPGKDAM 414

Query: 601 RGEPGIPGFPGNRGLMGQKGEIGPPGQ-QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKG 659
            G PG PG  G+ GL G  G  GPPG    +KG PG  GL G  GSPG PG  G KG  G
Sbjct: 415 -GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPG 473

Query: 660 -----------EPGIQGMPGASGLKGEPGATG------SPGEPGYMGLPGIQGKKGDKGN 702
                       PG+ G+PG  G+KG PG  G      SPG PG  GLPG  G  G    
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGA--- 530

Query: 703 QGEKGIQGQKGEN----GRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDG 758
           QG+ G++G+KGE     G+ G+PG  G++G  G KG  G  G PGV+G  G KGE  + G
Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590

Query: 759 LMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCD 818
             G  GP G PG PG  GP G  G PG     +   Q    V  A  P   ++G      
Sbjct: 591 EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPP-GEAGPRGELS 649

Query: 819 HCLSQHGSPGIPGPPGPIGPEGPRGL---------PGLPGRDGVPGL--VGVPGRPGVRG 867
                 G PG PGPPG  GP+GP G+         PGLPG DG PG+  +G PG PG +G
Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 868 LKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGK---DGDHGK 923
            +G PG  G  G  G  G PG  G PG PG +G P ++  G PG PG PG+    G+HG+
Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 924 PGIQGQPGPPG 934
            G+ G PG PG
Sbjct: 770 IGLPGLPGLPG 780



 Score =  369 bits (948), Expect = e-102
 Identities = 231/555 (41%), Positives = 272/555 (49%), Gaps = 89/555 (16%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPG---------------------QDGKPGYQGIAG 485
            PPG PG  G +G PG+PG  G  G PG                       G+PG +G AG
Sbjct: 905  PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 486  TPG------VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKG 539
             PG      VPG PG++G +GLPG  G PG  GD G  G PG PGL G+PGS G MG  G
Sbjct: 965  NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024

Query: 540  DKGS------------PGFYGKKGAKGEKGNAGF-----PGLPGPAGEPG------RHGK 576
             KG             PG  G  G +G+KG  G+     PG PGP G+PG      + G+
Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 577  DGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM 636
             G  G PG  G AG  GAPG  G+ G PG PG  G+ G  G KG +GPPG +G  G PG 
Sbjct: 1085 MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGF 1144

Query: 637  PGL---MGSNGSPGQPGTPGSKGSKGEPGI-QGMPGASGLKGEPGATGSPGEPGYMGLPG 692
            PG    MG  G  G+ G PG  G KGE G+ +  PG  G  G  GA G  G PG+ GLPG
Sbjct: 1145 PGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPG 1204

Query: 693  IQGKKGDKGNQGEKGIQGQKGENGRQG--IPGQQGIQGHHGAKGERGEKGEPGVRGA--I 748
             +G  GD G +G  GI+G  G  G  G  IPGQ G +G  G++G  G  G PG  G+  I
Sbjct: 1205 RKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI 1264

Query: 749  GSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVL 808
            G KG+ G  G  GP GP G  GD GP G  G  G PG                   LP  
Sbjct: 1265 GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG-------------------LPGP 1305

Query: 809  LQSGRIRNCDHCLSQHGSPGIPG---PPGPIGPEGPRGLPGLPGR------DGVPGLVGV 859
                  +       + G+PG  G   PPGPIGP+GP G+ G PG        G PG  G 
Sbjct: 1306 RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT 1365

Query: 860  PGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKD 918
            PG PG++G  G PG  G  G  G  G PG+ G PG PGP G  G   +G  G+PG  G D
Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG--NKGSKGEPGPAGSD 1423

Query: 919  GDHGKPGIQGQPGPP 933
            G  G  G +G  G P
Sbjct: 1424 GLPGLKGKRGDSGSP 1438



 Score =  367 bits (941), Expect = e-101
 Identities = 233/536 (43%), Positives = 268/536 (50%), Gaps = 55/536 (10%)

Query: 439  STPAPCIC-PPGKPGLQGPKGDPGLPGNPGY---PGQPGQDGKPGYQGIAGTPGVPGSPG 494
            STP P    PPG PG  GP+G PG+PG+ G    PG PG DG+PG  GI    G PG PG
Sbjct: 651  STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI----GFPGPPG 706

Query: 495  IQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGE--MGAKGDKGSPGFYGKKGA 552
             +G +G PG KG  G  G  G+ GLPG PGL   PG+KGE  +   G  G+PGF G++G 
Sbjct: 707  PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGN 763

Query: 553  KGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ--DGTRGEPGIPGFP 610
             GE G  G PGLPG  G PG  G DG  G PG  G  G  G PG+  +G RG  G+PG  
Sbjct: 764  SGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823

Query: 611  GNRGLMGQKGEIGP--------------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG 656
            G +G  G++G+ GP              PG+ G  G PG  G MG  G  G PG PG  G
Sbjct: 824  GLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG 883

Query: 657  SKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENG 716
              GE G+ GM G  G  G PG  G+PG PG  G PGI G KG +G  G KG QG KG  G
Sbjct: 884  PPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPG 943

Query: 717  RQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776
               I    G +G  G KG  G  GE G RG  G  G  G+ GL GPAGP G  GD G  G
Sbjct: 944  PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTG 1003

Query: 777  PPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI 836
             PG  G  G   S   +    +   R  L    ++GR             PG+PG  G  
Sbjct: 1004 NPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR-------------PGLPGIHGLQ 1050

Query: 837  GPEGPRGL-----PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQG 890
            G +G  G      PG PG  G PGL G  G+ G  G  G PG  G  G +G  G PG  G
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 891  PPGPPGPEGPPGISKE----GPPG---DPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
             PG PGP G  G        GPPG    PGLPG  G  G  GI+G  G  GI  P+
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA 1166



 Score =  358 bits (920), Expect = 1e-98
 Identities = 244/621 (39%), Positives = 293/621 (47%), Gaps = 131/621 (21%)

Query: 432 NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQD--GKPGYQGIAGTPGV 489
           +GP  V  +P        +PGL+G  G PGL G+ G  G+PG+D  G PG  G AG+PG+
Sbjct: 374 SGPPGVPGSPGS-----SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGL 428

Query: 490 PGSPGIQGA-------------RGLPGYKGEPGR---DGDKGDRGL--------PGFPGL 525
           PGSPG  G               GLPGY G PG    DG KG+ GL        PG PGL
Sbjct: 429 PGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGL 488

Query: 526 HGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGK-------DG 578
            G+PG  G  G  G +G+ G  G  G+ G  G  GFPG PG  G+PG  G+       +G
Sbjct: 489 PGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG 548

Query: 579 LMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRG---LMGQKGEIGPPGQQGKKGAPG 635
            +G PG  G  G PG  G DG  G PG+ G PG +G   L G+KG+ GPPG  G  G+PG
Sbjct: 549 QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPG 608

Query: 636 M--------------PGLMGSNGSPGQPGTPGSKGSKGE-------------------PG 662
                          PGL G+ G PG PG PG  G +GE                   PG
Sbjct: 609 PAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668

Query: 663 IQG---MPGASGLKGEPGATGSPGEPGY--MGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
            QG   +PG+ G  G+PG  G  GEPG   +G PG  G KGD+G  G KG  G  G+ G 
Sbjct: 669 PQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGE 728

Query: 718 QGIPGQQGIQGHHGA-----------------KGERGEKGEPGVRGAIGSKGESGVDGLM 760
            G+PG+ G+ G  G                  +G  GE GE G+ G  G  G  G +GL 
Sbjct: 729 PGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLD 788

Query: 761 GPAGPKGQPGDPGPQGPPG--LDGKPGREFSEQFIRQVCTDVIRAQLPVLL----QSGRI 814
           GP G  GQPG PG QGPPG  ++G  G +                 LP L     Q GR 
Sbjct: 789 GPRGDPGQPGPPGEQGPPGRCIEGPRGAQ----------------GLPGLNGLKGQQGRR 832

Query: 815 RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                     G PGIPG     G  G  G PG+PG  G  G +G  G PG  G+ G PG 
Sbjct: 833 GKT----GPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 875 NGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           +G  G  GF  PG  GPPGPPG  G PG       G PG+PG  G  G PG +G+ G  G
Sbjct: 888 DGVIGMMGF--PGAIGPPGPPGNPGTPG-----QRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 935 ICDPSLCFSVIA-RRDPFRKG 954
              PS    VI  + +P  KG
Sbjct: 941 NPGPSEISHVIGDKGEPGLKG 961



 Score =  346 bits (887), Expect = 7e-95
 Identities = 235/565 (41%), Positives = 274/565 (48%), Gaps = 93/565 (16%)

Query: 444 CICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG---SPGIQGARG 500
           C C  G  G +G KG PG PG+PG  G  G +G PG QG  G PG+PG   S G++G  G
Sbjct: 39  CFCD-GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISG 97

Query: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS------PGFYGKKGAKG 554
           LPG+ G PG  G  G+ G  G  G+ G  GSKGE G  G  G+      PG  G KG KG
Sbjct: 98  LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKG 157

Query: 555 -----------EKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
                       KG+ G PG PGP G PG  G  G +G PG  G  G PGA G  G +G 
Sbjct: 158 APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGH 217

Query: 604 PG--IPGFPGNRGLMGQKGEIGPPG-----------QQGKKGAPGMPGLMGSNGSPGQPG 650
            G  + G  G RG+ G  G  GPPG           +   KG  G  G MG  G PG  G
Sbjct: 218 MGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277

Query: 651 TPG-----SKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGE 705
            PG      KG+ G+PG+QG PG  G+ G PG+ G  G  G+ GL G  G KG KG+ G 
Sbjct: 278 LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 706 KGIQG---------QKGENGRQGIPGQQGIQGHHGAKGERGEKG-----EPGVRGAIGSK 751
            G +G         +KG+ G  G PG +G +G  G  G  G  G      PG+RGA G  
Sbjct: 338 PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397

Query: 752 GESGVDGLMGPAG--PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLL 809
           G  G  G  G  G    G PG PG  G PGL G PG       I      V R   P   
Sbjct: 398 GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI------VFRKGPP--- 448

Query: 810 QSGRIRNCDHCLSQH-GSPGIPGPPGPIGPEG--------PRGLPGLPGRDGVPGLVGVP 860
                   DH L  + GSPGIPG  GP G  G          G PGLPG  G+ G+ G+P
Sbjct: 449 -------GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501

Query: 861 GRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGPPGPPGPEG----PPGISKEGPPGDPGLP 915
           GR G  GLKG PG  G  G  GF G+PG QG PG  G +G    P G  + G PGDPGL 
Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG--QVGVPGDPGLR 559

Query: 916 GK------DGDHGKPGIQGQPGPPG 934
           G+      DG  G PG++G PGP G
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKG 584



 Score =  308 bits (788), Expect = 2e-83
 Identities = 192/433 (44%), Positives = 226/433 (52%), Gaps = 49/433 (11%)

Query: 551 GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
           GAKGEKG  GFPG PG  G+ G  G +GL G  G KG  G PG  G  G RG  G+PGF 
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 611 GNRGLMGQKGEIGP------PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG-------- 656
           G+ GL G  G  GP      PG  G KG  G PGL G+ G PG PG  G KG        
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 657 ------SKGEPGIQGMPGASGLKGE---PGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707
                 +KG+PG+ G PG  GL G    PG  G PG PG+ G PG  G +G KG+ GE+ 
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 708 IQGQKGENGRQGIPGQQGIQGH-----HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGP 762
           I G KGE G +G+ G  G  G       G       KGE G +GA+G  G  G  GL G 
Sbjct: 223 I-GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 763 A--GPKGQPGDPGPQGPPGLDGKPGREFSE------QFIRQVCTDVIRAQLPVLLQSGRI 814
           +    KG PGDPG QG PG DG PG   SE       F   +  D I+ Q   +   G  
Sbjct: 282 SYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR 341

Query: 815 RNCDH--CLSQHGSPGIPGPPGP---IGPEGPRGLPGLPGRDGV--PGLVGVPGRPGVRG 867
              ++     + G  G PGPPGP    GP+GP G PG+PG  G   PGL G PG PG++G
Sbjct: 342 GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKG 401

Query: 868 LKGLPGRNGE--KGSQGF-GYPGEQGPPGPPGPEGPPG--ISKEGPPGDPGLPGKDGDHG 922
            KG  GR G+   G+ G  G  G  G PG PGP GPPG  + ++GPPGD GLPG  G  G
Sbjct: 402 SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461

Query: 923 KPGIQGQPGPPGI 935
            PG+ G  G PG+
Sbjct: 462 IPGVDGPKGEPGL 474



 Score =  286 bits (731), Expect = 8e-77
 Identities = 172/387 (44%), Positives = 193/387 (49%), Gaps = 45/387 (11%)

Query: 450  KPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPG 509
            +PG  GP GDPGLPG+ G  G+ GQ G PG+ G AG  G PGSPG  G  G PG  G+ G
Sbjct: 1063 RPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122

Query: 510  RDGDKGDRGLPGF---PGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
              G KG  G PG    PGL G PGS G MG +GD+G  G  G  G KGE G    P  PG
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP--PG 1180

Query: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMG-----QKGE 621
            P G PG  G  G  G+PGF G  G  GA G  G RG  GI GFPG  GL G     Q G 
Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGN 1240

Query: 622  IGPPGQQGKKGAPGMPGLMGSN--------------------------GSPGQ---PGTP 652
             GPPG +G  GAPG PG  GS+                          G PG+   PGTP
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300

Query: 653  GSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN------QGEK 706
            G  G +G+PG QG PG  G KG PG  GS G PG +G  G  G +GD G        G  
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360

Query: 707  GIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPK 766
            G  G  GE G QG PG  G  G+ G  G RG+ G+ G  G  G  GE G  G  G  GP 
Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPA 1420

Query: 767  GQPGDPGPQGPPGLDGKPGREFSEQFI 793
            G  G PG +G  G  G P    +  F+
Sbjct: 1421 GSDGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  270 bits (691), Expect = 4e-72
 Identities = 181/458 (39%), Positives = 211/458 (46%), Gaps = 91/458 (19%)

Query: 536 GAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP 595
           GAKG+KG  GF G  G+ G+KG  G  GLPGP G  G  G  GL GS G +G +G PG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSK 655
           G       PG+PG PGN G  G  G  G  G +G++G PG+PG +G  G PG  G  G K
Sbjct: 103 GS------PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 656 GS-----------KGEPGIQGMPGASGLKGEPG---ATGSPGEPGYMGLPGIQGKKGDKG 701
           G+           KG+PG+ G PG  GL G PG     G PG PG+ G PG  G +G KG
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 702 NQGEKGIQGQKGENGRQGIPGQQGIQGH-----HGAKGERGEKGEPGVRGAIGSKGESGV 756
           + GE+ I G KGE G +G+ G  G  G       G       KGE G +GA+G  G  G 
Sbjct: 217 HMGERVI-GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGP 275

Query: 757 DGLMGPA--GPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRI 814
            GL G +    KG PGDPG QG PG D                                 
Sbjct: 276 SGLPGESYGSEKGAPGDPGLQGKPGKD--------------------------------- 302

Query: 815 RNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
                        G+PG PG  G +G RG PGL G DG+ G  G  G PG RG       
Sbjct: 303 -------------GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349

Query: 875 NGEKGSQGFGYP----GEQGPPGPPGPEGPPGI------SKEGPPGDPGLPGKDGDHGKP 924
             EKG +G   P    G +GP GP GP G PG          G PG PGL G  G+ G+P
Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409

Query: 925 G--IQGQPGPPGIC-DPSLCFSVIARRDP----FRKGP 955
           G    G PG PG    P L  S      P    FRKGP
Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447



 Score =  253 bits (645), Expect = 8e-67
 Identities = 148/356 (41%), Positives = 175/356 (49%), Gaps = 65/356 (18%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGT------------PGVPGSPG 494
            PPG  G  GP+G PG PG+PG PG+PG  G  G++GI G             PG PGSPG
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 495  IQGARG----------------------LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSK 532
              G RG                       PG +G PG  G KGDRG PGFPGL G  G+ 
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 533  GEMGAKGDKGSPGFYG-----------KKGAKGEKGNAGFPGLPGPAGEPGRH-----GK 576
            G+ G +G  G  GF G           + G +G  G+ G PG PGP G PG H     G 
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269

Query: 577  DGLMGSPGFKG------------EAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKG---E 621
             G MG PG KG              G+PG PG  G RG+PG  GFPG +G  G  G    
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 622  IGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGS 681
            IGPPG  G KG PG+ G  G+      PG+PG  G+ GEPG+QG PG  G  G  G  G 
Sbjct: 1330 IGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389

Query: 682  PGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             G+PG  G PG  G  G+KGN+G KG  G  G +G  G+ G++G  G       RG
Sbjct: 1390 RGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  207 bits (528), Expect = 3e-53
 Identities = 128/291 (43%), Positives = 145/291 (49%), Gaps = 45/291 (15%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            IPG  GE      + G   AP   P G PG QG KGD G PG PG PG+ G  G  G +G
Sbjct: 1162 IPGPAGE----KGETGLLRAPP-GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG 1216

Query: 483  IAGTPGVPGSPGIQGA--------RGLPGYKGEPGRDGD-----------KGDRGLPGFP 523
              G  G PG PG+ GA        RG PG +G PG  G            KGD+G  G P
Sbjct: 1217 PTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP 1276

Query: 524  GLHGMPGSKGEMGAKG------------DKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEP 571
            G  G PG+ G+MG  G             +G PGF G  G KGEKGN GF G  GP G  
Sbjct: 1277 GPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPI 1336

Query: 572  GRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKK 631
            G  G  G+ G PG       PG+PG  GT GEPG+ G PG  G  G  G  GP G+ GK 
Sbjct: 1337 GPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKD 1396

Query: 632  GAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
            G P         G+PG  G  G+KGSKGEPG  G  G  GLKG+ G +GSP
Sbjct: 1397 GKP---------GTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score =  173 bits (438), Expect = 8e-43
 Identities = 114/299 (38%), Positives = 131/299 (43%), Gaps = 39/299 (13%)

Query: 658 KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
           KG+    G  G  G KG PG  GSPG+ G+ G  G+ G +G KG  G  G+ G KG  G 
Sbjct: 36  KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGI 95

Query: 718 QGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGP 777
            G+PG  G  G  G  G  G  G  GV G  GSKGE G  GL G  G    PG PG  G 
Sbjct: 96  SGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLG---YPGIPGAAGL 152

Query: 778 PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIG 837
            G  G P +E   +                             L   G PG+PG PGP G
Sbjct: 153 KGQKGAPAKEEDIE-----------------------------LDAKGDPGLPGAPGPQG 183

Query: 838 PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRN--GEKGSQGFGYPGEQGPPGPP 895
             GP G PG  G  G PG  G PG  G RG KG  G    G KG +G      +G  GPP
Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGV-----KGLTGPP 238

Query: 896 GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKG 954
           GP G   ++  GP     L G+ GD G  G  G PGP G+   S      A  DP  +G
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQG 297



 Score =  141 bits (356), Expect = 3e-33
 Identities = 88/200 (44%), Positives = 97/200 (48%), Gaps = 15/200 (7%)

Query: 424  PGFNGECLNG-PSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            PG  G  + G   D GS   P   P G PG  G  G PG  G PG PG PG  G PG+QG
Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPG--PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRG------LPGFPGLHGMPGSKGEMG 536
              G  G  G+PG  G+ G PG  G  G  G +GD G      LPG PG  G PG  G  G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 537  AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPG 596
              G  G PG  G  G +G+ G  G PG PGPAGE G        GS G  G AGS G PG
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN------KGSKGEPGPAGSDGLPG 1427

Query: 597  QDGTRGEPGIPGFPGNRGLM 616
              G RG+ G P     RG +
Sbjct: 1428 LKGKRGDSGSPATWTTRGFV 1447


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  392 bits (1007), Expect = e-109
 Identities = 240/566 (42%), Positives = 280/566 (49%), Gaps = 77/566 (13%)

Query: 433 GPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGY---------PGQPGQDGKPGYQGI 483
           GPS     P P    PG PG QG +G PG PG PG          PG PG++G  G  G 
Sbjct: 182 GPSGPRGLPGP----PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGK 237

Query: 484 AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
            G PG  G PG QGARGLPG  G PG  G +G  GL G  G  G  G KGE G+ G+ G+
Sbjct: 238 PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297

Query: 544 PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
           PG  G +G  GE+G    PG PGPAG  G  G  G  G PG  G AG PG PG  G +GE
Sbjct: 298 PGQMGPRGLPGERGR---PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGE 354

Query: 604 PGIPGFPGNRGLMGQKGEIGPPG---------------QQGKKGA---------PGMPGL 639
            G  G  G+ G  G +GE GPPG               Q G KGA         PG PG 
Sbjct: 355 AGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGA 414

Query: 640 MGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGAT---------------GSPGE 684
            G +G  G  G PG KG+ GEPG  G  G +G KGEPG                 G+ GE
Sbjct: 415 RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGE 474

Query: 685 PGYMGLPGIQGKKGDKGNQ---GEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGE 741
           PG  GLPG  G++G  G++   G  G+ G KG  G +G PG  G +G  G  G  GE G 
Sbjct: 475 PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL 534

Query: 742 PGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGK------PGREFSEQFIRQ 795
           PG +G  GS G  G DG  GP GP GQ G PGP GPPG  G+      PG + +     +
Sbjct: 535 PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK 594

Query: 796 VCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLP---GLPGRDG 852
                +      +  +G+    D      G PG  GP G  G +GP G P   GLPG  G
Sbjct: 595 AGERGVPGPPGAVGPAGK----DGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAG 650

Query: 853 VPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGIS----KEGP 908
            PG  G PG  GV G  G PG +G +G +GF  PGE+G  GPPGP GP G +     +G 
Sbjct: 651 PPGEAGKPGEQGVPGDLGAPGPSGARGERGF--PGERGVQGPPGPAGPRGANGAPGNDGA 708

Query: 909 PGDPGLPGKDGDHGKPGIQGQPGPPG 934
            GD G PG  G  G PG+QG PG  G
Sbjct: 709 KGDAGAPGAPGSQGAPGLQGMPGERG 734



 Score =  392 bits (1007), Expect = e-109
 Identities = 222/502 (44%), Positives = 265/502 (52%), Gaps = 24/502 (4%)

Query: 447 PPGKPGLQGPKGDPGLPGNPGYPG---QPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPG 503
           P G  G QG +G+PG PG  G  G    PG DG+PG +G  G PG+ G+PG  GARG  G
Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419

Query: 504 YKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPG---FYGKKGAKGEKGNAG 560
            +G  G  G KG+ G PG PG  G  G+KGE G  G +G PG     GK+GA+GE G  G
Sbjct: 420 PQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTG 479

Query: 561 FPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKG 620
            PG PG  G PG  G  G  G  G KG AG  G+PG  G +G PG  G PG  GL G KG
Sbjct: 480 LPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539

Query: 621 EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATG 680
             G PG  G  G  G PG  G +G PG PG PG++G  G  G  G  GA+G  G+ G  G
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG 599

Query: 681 SPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKG 740
            PG PG +G  G  G+ G +G  G  G  G++GE G  G PG QG+ G  G  GE G+ G
Sbjct: 600 VPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG 659

Query: 741 EPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDV 800
           E GV G +G+ G SG  G  G  G +G  G PGP GP G +G PG + ++          
Sbjct: 660 EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKG--------- 710

Query: 801 IRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVP 860
             A  P    S           + G+ G+PGP G  G  GP+G  G PG+DGV GL G  
Sbjct: 711 -DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI 769

Query: 861 GRPGVRGLKGLPGRNGEKGSQG----FGYPGEQGPPGPPGP---EGPPGI-SKEGPPGDP 912
           G PG  G  G  G +G  G  G     G PG++G PGPPGP    GPPG   + G  G+P
Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829

Query: 913 GLPGKDGDHGKPGIQGQPGPPG 934
           G  G  GD G PG  G  GPPG
Sbjct: 830 GDAGAKGDAGPPGPAGPAGPPG 851



 Score =  384 bits (985), Expect = e-106
 Identities = 229/523 (43%), Positives = 258/523 (49%), Gaps = 61/523 (11%)

Query: 439 STPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGA 498
           S P P + P G  GL GP G PG  G  G PG+PG+ G  G  G  G PG PG  G  G 
Sbjct: 176 SVPGP-MGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGE 234

Query: 499 RGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGN 558
            G PG  GE G  G +G RGLPG  GL GM G +G  G  G KG  G  G KG  G  G 
Sbjct: 235 AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294

Query: 559 AGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQ 618
            G PG  GP G PG  G+ G  G  G +G  G+ GA G  G  G  G PGFPG    +G 
Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG---AVGA 351

Query: 619 KGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA 678
           KGE GP G +G +G  G+       G PG PG  G+ G  G PG  G PGA G  G PG 
Sbjct: 352 KGEAGPQGPRGSEGPQGV------RGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405

Query: 679 TGSPGEPGYMGLPGIQGK---KGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGE 735
            G+PG PG  G  G QG     G KGN GE G  G KG+ G +G PG  G+QG  G  GE
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE 465

Query: 736 ---RGEKGE---------PGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGK 783
              RG +GE         PG RG  GS+G  G DG+ GP GP G+ G PGP GP G  G+
Sbjct: 466 EGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGE 525

Query: 784 PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRG 843
            GR                A LP                  GSPG PGP G  GP GP G
Sbjct: 526 AGRPG-------------EAGLP------------GAKGLTGSPGSPGPDGKTGPPGPAG 560

Query: 844 LPGLPGRDGVPGL---VGVPGRPGVRGLKGLPGRNGEKGSQG-------FGYPGEQGPPG 893
             G PG  G PG     GV G PG +G  G PG+ GE+G  G        G  GE G  G
Sbjct: 561 QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG 620

Query: 894 PPGPEGPPG-ISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
           PPGP GP G   ++GP G PG  G  G  G PG  G+PG  G+
Sbjct: 621 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGV 663



 Score =  384 bits (985), Expect = e-106
 Identities = 241/568 (42%), Positives = 280/568 (49%), Gaps = 55/568 (9%)

Query: 424  PGFNGEC-LNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGY---PGQPGQDGKPG 479
            PG +G     GP+    +P P   P G PG  G  G+ GLPG  G    PG PG DGK G
Sbjct: 496  PGADGVAGPKGPAGERGSPGPA-GPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG 554

Query: 480  YQGIAGTPGVPGSPGIQGARG------LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKG 533
              G AG  G PG PG  GARG       PG KG  G  G  G+RG+PG PG  G  G  G
Sbjct: 555  PPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDG 614

Query: 534  EMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPG 593
            E GA+G  G  G  G++G +G  G+ GF GLPGPAG PG  GK G  G PG  G  G  G
Sbjct: 615  EAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSG 674

Query: 594  APGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGT-- 651
            A G+ G  GE G+ G PG  G  G  G  G  G +G  GAPG PG  G+ G  G PG   
Sbjct: 675  ARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERG 734

Query: 652  ----PGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707
                PG KG +G+ G +G  G+ G  G  G TG  G PG  G PG +G+ G  G  G  G
Sbjct: 735  AAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794

Query: 708  IQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKG 767
             +G  G+ G  G PG  G  G  GA G+ G KGEPG  GA G  G  G  G  GP GP G
Sbjct: 795  ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 768  QPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQL-------PVLLQSGRIRNCDHC 820
              G PG +G  G  G PG         +V                P   + G+    +  
Sbjct: 855  NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGE-- 912

Query: 821  LSQHGSPGIPGPPGPIGP---------EGPRGLPGLPGRDGVPG---LVGVPGRPGVRGL 868
                G PG  GPPGP GP         +GP G PG PG  G+ G   +VG+PG+ G RG 
Sbjct: 913  TGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGF 972

Query: 869  KGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEG---PPGIS-KEGPPGDPGLPGKDGDHGK 923
             GLPG +GE G QG  G  GE+GPPGP GP G   PPG S +EG PG  G PG+DG  G 
Sbjct: 973  PGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGA 1032

Query: 924  ------------PGIQGQPGPPGICDPS 939
                        PG  G PG PG   P+
Sbjct: 1033 KGDRGETGPAGPPGAPGAPGAPGPVGPA 1060



 Score =  380 bits (977), Expect = e-105
 Identities = 239/565 (42%), Positives = 270/565 (47%), Gaps = 70/565 (12%)

Query: 432  NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG 491
            +G +     P P   P G+ G QGP G PG  G PG  G PG+ GKPG QG+ G  G PG
Sbjct: 613  DGEAGAQGPPGPA-GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG 671

Query: 492  SPGIQGARGLPGYKG---------------EPGRDGDKGDRGLPGFPG------LHGMPG 530
              G +G RG PG +G                PG DG KGD G PG PG      L GMPG
Sbjct: 672  PSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPG 731

Query: 531  SKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAG 590
             +G  G  G KG  G  G KGA G  G  G  GL GP G PG  G  G  G  G  G AG
Sbjct: 732  ERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAG 791

Query: 591  SPGAPGQDGTRGEPGIPG---FPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPG 647
              GA G  G RGEPG PG   F G  G  GQ G  G PG  G KG  G PG  G  G PG
Sbjct: 792  PTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG 851

Query: 648  Q------PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKG 701
                   PG  G++GS G PG  G PGA+G  G PG +G+ G PG    PG  GK+G KG
Sbjct: 852  PIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGP---PGPAGKEGGKG 908

Query: 702  NQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKG--------- 752
             +GE G  G+ GE G  G PG  G +G  GA G  G  G PG +G  G +G         
Sbjct: 909  PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968

Query: 753  ---------ESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRA 803
                      SG  G  GP+G  G+ G PGP GPPGL G PG    E       +     
Sbjct: 969  ERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDG 1028

Query: 804  QLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP---EGPRGLPGLPGRDGVPGLVGVP 860
                    G            G+PG PG PGP+GP    G RG  G  G  G  G VG  
Sbjct: 1029 SPGAKGDRGETGPA----GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGAR 1084

Query: 861  GRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGP---PGPEGPPGIS----KEGPP 909
            G  G +G +G  G  GE+G +G     G+ G QGPPGP   PG +GP G S      GPP
Sbjct: 1085 GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPP 1144

Query: 910  GDPGLPGKDGDHGKPGIQGQPGPPG 934
            G  G PGKDG +G PG  G PGP G
Sbjct: 1145 GSAGAPGKDGLNGLPGPIGPPGPRG 1169



 Score =  377 bits (967), Expect = e-104
 Identities = 221/539 (41%), Positives = 260/539 (48%), Gaps = 69/539 (12%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
           PGF G    GPS           P G  G  GPKG+ G PG PG  G  G  G+PG  G+
Sbjct: 409 PGFPGA--RGPSG----------PQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGV 456

Query: 484 AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
            G PG  G  G +GARG PG  G PG  G++G  G  GFPG  G+ G KG  G +G  G 
Sbjct: 457 QGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGP 516

Query: 544 PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
            G  G  G  G  G AG PG  G  G PG  G DG  G PG  G+ G PG PG  G RG+
Sbjct: 517 AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQ 576

Query: 604 PGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE--- 660
            G+ GFPG +G  G+ G+ G  G  G  GA G  G  G  G+ G PG  G  G +GE   
Sbjct: 577 AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP 636

Query: 661 ---PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR 717
              PG QG+PG +G  GE G  G  G PG +G PG  G +G++G  GE+G+QG  G  G 
Sbjct: 637 AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP 696

Query: 718 QGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGP 777
           +   G  G  G+ GAKG+ G  G PG +GA G +G  G  G  G  GPKG  GD GP+G 
Sbjct: 697 R---GANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753

Query: 778 PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIG 837
            G  GK G       +R +   +                        G PG  G PG  G
Sbjct: 754 DGSPGKDG-------VRGLTGPI------------------------GPPGPAGAPGDKG 782

Query: 838 PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG----FGYPGEQGPPG 893
             GP G  G  G  G PG  G PG PG  G  G PG +G+ G++G     G  G+ GPPG
Sbjct: 783 ESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPG 842

Query: 894 PPGPEGPPG-------------ISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
           P GP GPPG                 GPPG  G PG  G  G PG  G  GPPG   P+
Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPA 901



 Score =  361 bits (927), Expect = 2e-99
 Identities = 219/541 (40%), Positives = 255/541 (47%), Gaps = 66/541 (12%)

Query: 441  PAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARG 500
            P   + P GK G  G +G PG  G  G  G+ G  G PG+QG+ G  G PG  G  G +G
Sbjct: 603  PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQG 662

Query: 501  LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAG 560
            +PG  G PG  G +G+RG PG  G+ G PG  G  GA G  G+ G  G  GA G  G+ G
Sbjct: 663  VPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQG 722

Query: 561  FPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKG 620
             PGL G  GE G  G  G  G  G  G  G+ G+PG+DG RG  G  G PG  G  G KG
Sbjct: 723  APGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKG 782

Query: 621  EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGE---PG 677
            E GP G  G  GA G PG  G  G PG  G  G  G+ G+PG +G PG +G KG+   PG
Sbjct: 783  ESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPG 842

Query: 678  ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
              G  G PG +G  G  G KG +G+ G  G  G  G  GR G PG  G  G  G  G  G
Sbjct: 843  PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAG 902

Query: 738  EKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVC 797
            ++G  G RG  G  G  G  G  GP GP G+ G PG  GP G  G PG +          
Sbjct: 903  KEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQ---------- 952

Query: 798  TDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIP------------------GPPGPIGPE 839
               I  Q  V+   G+         + G PG+P                  GPPGP+GP 
Sbjct: 953  --GIAGQRGVVGLPGQ-------RGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP 1003

Query: 840  GPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG----------------F 883
            G  G PG  GR+G PG  G PGR G  G KG  G  G  G  G                 
Sbjct: 1004 GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS 1063

Query: 884  GYPGEQGPPGPPGPEGPPG----ISKEGPPGDPGLPGKDGD------HGKPGIQGQPGPP 933
            G  GE GP GP GP GP G       +GP GD G  G+ GD       G  G+QG PGPP
Sbjct: 1064 GDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPP 1123

Query: 934  G 934
            G
Sbjct: 1124 G 1124



 Score =  351 bits (901), Expect = 2e-96
 Identities = 212/508 (41%), Positives = 246/508 (48%), Gaps = 62/508 (12%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPG------------VPGSPGIQ 496
            G PG  G KGD G PG PG  G PG  G PG +G AG PG              GSPG  
Sbjct: 701  GAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760

Query: 497  GARGL------PGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKG---SPGFY 547
            G RGL      PG  G PG  G+ G  G  G  G  G PG +GE G  G  G    PG  
Sbjct: 761  GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGAD 820

Query: 548  GKKGAKGE------KGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGA------- 594
            G+ GAKGE      KG+AG PG  GPAG PG  G  G  G+ G +G AG PGA       
Sbjct: 821  GQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880

Query: 595  -----PGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQ- 648
                 PG  G  G PG PG  G  G  G +GE GP G+ G+ G PG PG  G  GSPG  
Sbjct: 881  GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940

Query: 649  -----PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ 703
                 PGTPG +G  G+ G+ G+PG  G +G PG  G  GEPG  G  G  G++G  G  
Sbjct: 941  GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 704  GEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPA 763
            G  G+ G  GE+GR+G PG +G  G  G+ G +G++GE G  G  G+ G  G  G +GPA
Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPA 1060

Query: 764  GPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQ 823
            G  G  G+ GP GP G  G  G                  Q P   +       D  +  
Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGAR-----------GPAGPQGPRGDKGETGEQGDRGIKG 1109

Query: 824  H----GSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKG 879
            H    G  G PGPPG  G +GP G  G  G  G PG  G PG+ G+ GL G  G  G +G
Sbjct: 1110 HRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRG 1169

Query: 880  SQGFGYPGEQGPPGPPGPEGPPGISKEG 907
              G    G  GPPGPPGP GPPG    G
Sbjct: 1170 RTGDA--GPVGPPGPPGPPGPPGPPSAG 1195



 Score =  290 bits (741), Expect = 6e-78
 Identities = 173/426 (40%), Positives = 207/426 (48%), Gaps = 64/426 (15%)

Query: 434  PSDVG-STPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI---AGTPGV 489
            P D G S P+    P G  G  G +G+PG PG  G+ G PG DG+PG +G    AG  G 
Sbjct: 778  PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGD 837

Query: 490  PGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS------ 543
             G PG  G  G PG  G  G  G KG RG  G PG  G PG+ G +G  G  G+      
Sbjct: 838  AGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGP 897

Query: 544  PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
            PG  GK+G KG +G  G  G PG  G PG  G  G  GSPG  G AG+PG PG  G  G+
Sbjct: 898  PGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQ 957

Query: 604  PGIPGFPGNRGLMG---------QKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGS 654
             G+ G PG RG  G         + G+ GP G  G++G PG  G  G  G PG+ G  G+
Sbjct: 958  RGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA 1017

Query: 655  KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGI--------------------- 693
             G++G PG  G PGA G +GE G  G PG PG  G PG                      
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP 1077

Query: 694  ------------QGKKGDKGNQGEKGIQGQKGENGRQGI------PGQQGIQGHHGAKGE 735
                        QG +GDKG  GE+G +G KG  G  G+      PG  G QG  GA G 
Sbjct: 1078 VGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGP 1137

Query: 736  RGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGD------PGPQGPPGLDGKPGREFS 789
             G +G PG  GA G  G +G+ G +GP GP+G+ GD      PGP GPPG  G P   F 
Sbjct: 1138 AGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFD 1197

Query: 790  EQFIRQ 795
              F+ Q
Sbjct: 1198 FSFLPQ 1203



 Score =  286 bits (732), Expect = 6e-77
 Identities = 173/423 (40%), Positives = 195/423 (46%), Gaps = 61/423 (14%)

Query: 527 GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586
           G+ G KG+ G +G +G  G  G+ G  G+ G  G PG PGP G PG  G      S G+ 
Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168

Query: 587 ----GEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGS 642
               G    PG  G  G RG PG PG PG +G  G  GE G PG  G  G  G PG  G 
Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228

Query: 643 NGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN 702
           NG  G+ G PG       PG +G PG  G +G PG  G PG  G+ G  G+ G KGD G 
Sbjct: 229 NGDDGEAGKPG------RPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP 282

Query: 703 QGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGP 762
            G KG  G  GENG    PGQ G +G     GERG  G PG  GA G+ G +G  G  GP
Sbjct: 283 AGPKGEPGSPGENGA---PGQMGPRG---LPGERGRPGAPGPAGARGNDGATGAAGPPGP 336

Query: 763 AGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLS 822
            GP G PG PG  G  G  G  G   SE                                
Sbjct: 337 TGPAGPPGFPGAVGAKGEAGPQGPRGSE-------------------------------- 364

Query: 823 QHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG 882
             G  G+ G PGP GP G  G  G PG DG PG  G  G PG+ G  G PG  G  G QG
Sbjct: 365 --GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQG 422

Query: 883 FGYP----GEQGPPGPPGPEGPPG-------ISKEGPPGDPGLPGKDGDHGKPGIQGQPG 931
            G P    G  G PG PG +G  G       +  +GPPG  G  GK G  G+PG  G PG
Sbjct: 423 PGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPG 482

Query: 932 PPG 934
           PPG
Sbjct: 483 PPG 485



 Score =  237 bits (604), Expect = 4e-62
 Identities = 158/418 (37%), Positives = 182/418 (43%), Gaps = 83/418 (19%)

Query: 543 SPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG 602
           SP      G +G KG+ G  G  GPAG PGR G                   PGQ G  G
Sbjct: 101 SPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDG------------------IPGQPGLPG 142

Query: 603 EPGIPGFPGNRGLMGQKGEIGPPGQQGKK-GAPGMPGLMGSNGSPGQPGTPGSKGSKGEP 661
            PG PG PG  GL G        G   K  G   +PG MG +G  G PG PG+ G +G  
Sbjct: 143 PPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQ 202

Query: 662 GIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIP 721
           G  G PG  G  G  G  G PG PG  G  G  GK G  G +G  G QG +G  G  G+P
Sbjct: 203 GPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLP 262

Query: 722 GQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAG---PKGQPGDPGPQGPP 778
           G +G +G  G  G +G+ G  G +G  GS GE+G  G MGP G    +G+PG PGP G  
Sbjct: 263 GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGAR 322

Query: 779 GLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIP-------- 830
           G DG  G                                       G PG          
Sbjct: 323 GNDGATGAA-------------------------------------GPPGPTGPAGPPGF 345

Query: 831 ----------GPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGS 880
                     GP GP G EGP+G+ G PG  G  G  G  G PG  G  G  G NG  G 
Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405

Query: 881 QGF-GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGD---HGKPGIQGQPGPPG 934
            G  G+PG +GP GP GP GPPG   +G  G+PG PG  GD    G+PG  G  GPPG
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPG--PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPG 461



 Score =  222 bits (566), Expect = 1e-57
 Identities = 151/392 (38%), Positives = 167/392 (42%), Gaps = 69/392 (17%)

Query: 562 PGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGE 621
           PG   P GE      DG   SP  +   G  G  G  G RG  G  G PG  G+ GQ G 
Sbjct: 82  PGAEVPEGECCPVCPDG-SESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGL 140

Query: 622 IGPPGQQGKKGAPGMPGLMG----------SNGSPGQPGTPGSKGSKGEPGIQGMPGASG 671
            GPPG  G  G PG+ G             S G    PG  G  G +G PG  G PG  G
Sbjct: 141 PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG 200

Query: 672 LKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG 731
            +G PG  G PG  G MG          +G  G  G  G  GE G+ G PG++G  G  G
Sbjct: 201 FQGPPGEPGEPGASGPMG---------PRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQG 251

Query: 732 AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQ 791
           A+G  G  G PG++G  G  G  G  G  GPAGPKG+PG PG  G PG  G         
Sbjct: 252 ARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP-------- 303

Query: 792 FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRD 851
                                            G PG  G PG  GP G RG  G  G  
Sbjct: 304 --------------------------------RGLPGERGRPGAPGPAGARGNDGATGAA 331

Query: 852 GVP---GLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEG 907
           G P   G  G PG PG  G KG  G  G +GS+G  G  GE GPPGP G  GP      G
Sbjct: 332 GPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGP-----AG 386

Query: 908 PPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
            PG  G PG  G +G PGI G PG PG   PS
Sbjct: 387 NPGADGQPGAKGANGAPGIAGAPGFPGARGPS 418



 Score =  195 bits (495), Expect = 2e-49
 Identities = 112/261 (42%), Positives = 128/261 (49%), Gaps = 10/261 (3%)

Query: 432  NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG 491
            +GP+    TP P     G  G +G  G PG  G  G+PG PG  G+PG QG +G  G  G
Sbjct: 940  DGPAGAPGTPGP----QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERG 995

Query: 492  SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKG 551
             PG  G    PG  G PG  G +G  G  G PG  G PG+KG+ G  G  G PG  G  G
Sbjct: 996  PPGPMGP---PGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052

Query: 552  AKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611
            A G  G A   G  G  GE G  G  G +G  G +G AG  G  G  G  GE G  G  G
Sbjct: 1053 APGPVGPA---GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKG 1109

Query: 612  NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASG 671
            +RG  G +G  GPPG  G++G  G  G  G  G PG  G PG  G  G PG  G PG  G
Sbjct: 1110 HRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRG 1169

Query: 672  LKGEPGATGSPGEPGYMGLPG 692
              G+ G  G PG PG  G PG
Sbjct: 1170 RTGDAGPVGPPGPPGPPGPPG 1190


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  392 bits (1007), Expect = e-109
 Identities = 260/652 (39%), Positives = 301/652 (46%), Gaps = 147/652 (22%)

Query: 411  DPEQNNRETACEIPGFNGECLNGP------SDVGSTPAPC--ICPPGKPGLQGPKGDPGL 462
            DP     E    IPGF G  L GP      +     P P    C  G PG+ G  G PG 
Sbjct: 787  DPGCPGAEGPAGIPGFLG--LKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGY 844

Query: 463  PGNPGYPG---QPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE------PGRDGD 513
            PG+PG PG   QPG  G PG  G+ G PG+PG PG  G  GLPG  G       PG  G 
Sbjct: 845  PGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGP 904

Query: 514  KGDRGLPGFPGL---------HGMPGSKGEMGAKGDKGSPGFYGKKGAKG---------- 554
            KG RGLPGFPG           G PG+KGE G KG  G PG  G +GAKG          
Sbjct: 905  KGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGE 964

Query: 555  -----------------------EKGNAGFPGLPGPAGEPGRHGKDGL-MGSPGFKGEAG 590
                                   E+G+ G PG+ G  GEPGR+G  G   G PG KG+ G
Sbjct: 965  MAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPG 1024

Query: 591  SPGAPGQDGT---------------RGEPGIPGFPGNRGLMGQKG----------EIGPP 625
             PG PG  G+               +GEPG PG PG  G+ G +G            GPP
Sbjct: 1025 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084

Query: 626  GQQGKKGAPG------------MPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLK 673
            G +G+ G+PG            +PG+ G  GSPG+PG PGS G  G PG  GMPG  G  
Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQP 1144

Query: 674  GE---PGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIP--GQQGIQG 728
            GE   PG  G  G+PG  G PGI+G  G  G  G  G++GQKG  G  G+   G  G  G
Sbjct: 1145 GEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVG 1204

Query: 729  HHGAKGERGEKGEPGVR--GAIGSKGESGVDGLMGPAGPKG----------QPGDPGPQG 776
              G KGERG+ G PG+   G  G KG  G  G  GP GP G           PG PG QG
Sbjct: 1205 IPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQG 1264

Query: 777  PPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI 836
            PPG DG  G          V  D++R +                    G  G+PGPPGP 
Sbjct: 1265 PPGPDGPRGAPGPPGLPGSV--DLLRGE-------------------PGDCGLPGPPGPP 1303

Query: 837  GPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPG 896
            GP GP G  G PG DG  G  G  G PG +G  G PG  GEKG  G   PG +GP G PG
Sbjct: 1304 GPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPG--PPGRKGPTGLPG 1361

Query: 897  PEGPPGISKE--------GPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSL 940
            P G PG   +        G PG PG+ G +G  G PG++G  GP    +P L
Sbjct: 1362 PRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGL 1413



 Score =  371 bits (952), Expect = e-102
 Identities = 240/595 (40%), Positives = 280/595 (47%), Gaps = 126/595 (21%)

Query: 448 PGKPGLQGPKGDPGLPGNPGYPGQ--PGQDGKPGYQGIAGTPG------------VPGSP 493
           PG+PGL GP G PG PG  G PG    GQ G PG  G  G+PG              G  
Sbjct: 213 PGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEK 272

Query: 494 GIQGARGLPGYKGEPGRDGD-----KGDRGLPGFPGLHGMPGSKGEMGAKGDKGS----- 543
           GI+G  G+ G  G PGR G+     KG++G+PGFPG  G PGS G  G  G KG      
Sbjct: 273 GIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVG 332

Query: 544 -PGFYGKKGAKGEKGNAGFPGLPG-----------PAGEPGRHGK--------------- 576
            PG +G  G KG+ GN G PG PG           P G+PG  G+               
Sbjct: 333 DPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGL 392

Query: 577 -----------------DGLMGSPGFKGEAGSPG----APGQDGTRGEPGIPGFPGNRGL 615
                             G  G PG  GEAG PG    APG+ G  G PG+PG PG +GL
Sbjct: 393 LGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGL 452

Query: 616 MGQ---------------KGEIGPPGQQGKKGAPGMPGLM----GSNGSPGQPGTPGSKG 656
            G                KG++GPPG +G KG  G  GL     G  G PG PG PG +G
Sbjct: 453 PGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQG 512

Query: 657 SKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENG 716
           SKG+ G+ G  G  G  G PGA G PG PG  G  G  G KG KG+     ++G KGE G
Sbjct: 513 SKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERG 572

Query: 717 RQGIPGQQGIQGHHGAKGERGEKGEPG--------VRGAIGSKGESGVDGLMGPAGPKGQ 768
             G PG  G  G HG  G  GEKG+PG          G  G  G  G  G  GP GP G 
Sbjct: 573 PDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL 632

Query: 769 --PGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCL-SQHG 825
             PG PG +G PG+ G PG               +R    +  Q G   +C+     +HG
Sbjct: 633 GFPGPPGERGHPGVPGHPG---------------VRGPDGLKGQKGDTISCNVTYPGRHG 677

Query: 826 SPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGY 885
            PG  GPPGP G  GP+G PGL G DG  G    PG PG   + G PG  G+ G  GFG 
Sbjct: 678 PPGFDGPPGPKGFPGPQGAPGLSGSDGHKGR---PGTPGTAEIPGPPGFRGDMGDPGFGG 734

Query: 886 PGEQGPPGPPGPEGPPGIS-KEGPPGDP-----GLPGKDGDHGKPGIQGQPGPPG 934
                P GPPGP G PG++ ++G PGDP     G PGK G  G PGI+G  G PG
Sbjct: 735 EKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPG 789



 Score =  370 bits (950), Expect = e-102
 Identities = 249/661 (37%), Positives = 296/661 (44%), Gaps = 181/661 (27%)

Query: 424  PGFNGECLNGPSDVGSTPA-PCICPPGK------PGLQGPKGDPGLPGN----------- 465
            PG  G  +NG   +   PA   + PPGK      PG++GP+GDPG PG            
Sbjct: 747  PGSPG--VNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLG 804

Query: 466  -------------PGYPGQPGQD---GKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPG 509
                         PG PG PG     G PG  G  G PG PGSPG  G +G PG  G PG
Sbjct: 805  LKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPG 864

Query: 510  RDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPG------ 563
              G KG  GLPG PG HG PG  G  G  GD G PG  G KG +G  G  GFPG      
Sbjct: 865  PAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPG 924

Query: 564  ---LPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT------RGEPGIPGFPGNRG 614
                PG  GEPG  G  GL G  G +G  G+ G PG +G       +G PG PG PG+ G
Sbjct: 925  AEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDG 984

Query: 615  LMGQKGEIGPPGQQGKKGAPGM---PGL-MGSNGSPGQPGTPGSKGSKGEPGIQGMPGAS 670
              G++G+ G PG QG++G PG    PG   G  G  GQPG PG  G  G  G++G  G  
Sbjct: 985  FPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFP 1044

Query: 671  GLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN-------------------------QGE 705
            GL G+ G  GSPG PG+ G+ G +G KG+KG+                          GE
Sbjct: 1045 GLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGE 1104

Query: 706  KGI---QGQKGENGRQGIPGQQ---GIQGHHGAKGERGEKGE------------------ 741
            +G+   QG +G  GR G PG     G  G HG  G RG+ GE                  
Sbjct: 1105 QGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGP 1164

Query: 742  PGVRGAIGSKGESGVDGL--------------MGPAGP------KGQPGDP--------- 772
            PG++G  GS G +G+ GL              +GP GP      KG+ GDP         
Sbjct: 1165 PGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPG 1224

Query: 773  -----GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSP 827
                 GP GPPG  G PG                         +G        +   G P
Sbjct: 1225 PRGKKGPPGPPGSSGPPG------------------------PAGATGRAPKDIPDPGPP 1260

Query: 828  GIPGPPGPIGPEGPRGLPGLPGR----------DGVPGLVGVPGRPGVRGLKGLPGRNGE 877
            G  GPPGP GP G  G PGLPG            G+PG  G PG PG  G KG PG +G+
Sbjct: 1261 GDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGK 1320

Query: 878  KGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGIC 936
             G +G  G+PG QGP G PGP G  G+        PG PG+ G  G PG +G+PGPP   
Sbjct: 1321 DGQKGPVGFPGPQGPHGFPGPPGEKGL--------PGPPGRKGPTGLPGPRGEPGPPADV 1372

Query: 937  D 937
            D
Sbjct: 1373 D 1373



 Score =  369 bits (947), Expect = e-102
 Identities = 223/526 (42%), Positives = 264/526 (50%), Gaps = 51/526 (9%)

Query: 447  PPGKPGL--QGPKGDPGLPGNPGYPGQPGQDGKPGYQG--------IAGTPGVPGSPGIQ 496
            P G PGL   GP G+ G PG PG+PG  G DG  G +G          G  G PG  G  
Sbjct: 626  PVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPP 685

Query: 497  GARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAK--G 554
            G +G PG +G PG  G  G +G PG PG   +PG  G    +GD G PGF G+KG+   G
Sbjct: 686  GPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPG---FRGDMGDPGFGGEKGSSPVG 742

Query: 555  EKGNAGFPGLPGPAGEPGRH--------GKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGI 606
              G  G PG+ G  G PG          GK GL G PG KG  G PG PG +G  G PG 
Sbjct: 743  PPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGF 802

Query: 607  PGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGM 666
             G  G +G  G  G  G PG  G     G PG+ G  G PG PG+PG+ G KG+PG  G 
Sbjct: 803  LGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGP 862

Query: 667  PGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGI 726
            PG +G+KG PG  G PG  G  GLPGI G  GD G  G  G +G +G  G  G PG++G 
Sbjct: 863  PGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGK 922

Query: 727  QGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKG------QPGDPGPQGPPGL 780
             G  G  G +GE GE G+ G  G +G  G  G +GP G +G      Q G PG  GPPG 
Sbjct: 923  PGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGD 982

Query: 781  DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG 840
            DG PG    +       T  ++ +     + GR         + G  G PGPPGP GP G
Sbjct: 983  DGFPGERGDKG------TPGMQGRRG---EPGRYGPPGFHRGEPGEKGQPGPPGPPGPPG 1033

Query: 841  PRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-----FGYPGEQGPPGPP 895
              GL G  G  G+PG  G PG PG  G  G+ G  G KG++G     FG PG +G PG P
Sbjct: 1034 STGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSP 1093

Query: 896  GPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLC 941
            G  G  G S     G+ GLPG  G  G PG   +PGPPG   P  C
Sbjct: 1094 GCPGHFGAS-----GEQGLPGIQGPRGSPG---RPGPPGSSGPPGC 1131



 Score =  365 bits (938), Expect = e-101
 Identities = 233/555 (41%), Positives = 277/555 (49%), Gaps = 91/555 (16%)

Query: 452 GLQGPKGDPGLPGNPGY---PGQPGQDGKPGYQGIAGTPGVPGSPGIQG--ARGLPGYKG 506
           G+QG +GDPGLPG PG     G  G  G PG  G+ G PG PG PG++G    G+ G  G
Sbjct: 184 GIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMG 243

Query: 507 EPGR---------------------DGDKGDRGLPGFPGLHGMPGSKGE--MGAKGDKGS 543
           +PG                       G+KG +G+PG  GL G PG KGE  +GAKG+KG 
Sbjct: 244 DPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGI 303

Query: 544 PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT--- 600
           PGF G +G  G  G+ GFPGL G  G  G  G  GL+G  G  G  G PG PG   T   
Sbjct: 304 PGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPL 363

Query: 601 --RGEPGIPGFPGNRG------------LMGQKGE-----IGPPGQQGKKGAPGMPGLMG 641
             +G PG PGFPG  G            L+G+ GE     IGPPG QG  G PG+PG  G
Sbjct: 364 PLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAG 423

Query: 642 SNG----SPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKK 697
             G    +PG+PG PGS G  G PG+QG+PG+S +    G  G  G  G +G PG +G K
Sbjct: 424 IPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPK 483

Query: 698 GDKGNQGEKGIQ-GQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGV 756
           G+KGN+G    + G  G  G  G+PG+QG +G  G  G  G KG+PG  GA G  G  G 
Sbjct: 484 GEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGK 543

Query: 757 DGLMGPAGPKGQPGDP------------GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQ 804
            G  GP G KG  GD             GP GPPG  G+PG    +    +         
Sbjct: 544 HGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGE--------- 594

Query: 805 LPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGL--PGRDGVPGLVGVPGR 862
                +       DH  +  G  G PGP GP G  GP G PGL  PG  G  G  GVPG 
Sbjct: 595 -----KGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGH 649

Query: 863 PGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHG 922
           PGVRG  GL G+ G+  S    YPG  GPPG  GP GP G    GP G PGL G DG   
Sbjct: 650 PGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFP--GPQGAPGLSGSDGH-- 705

Query: 923 KPGIQGQPGPPGICD 937
               +G+PG PG  +
Sbjct: 706 ----KGRPGTPGTAE 716



 Score =  364 bits (935), Expect = e-100
 Identities = 233/572 (40%), Positives = 279/572 (48%), Gaps = 98/572 (17%)

Query: 425  GFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPG----------------- 467
            GF G  L  P   G    P +  PG PG    +G PG+PG+PG                 
Sbjct: 613  GFPGP-LGPPGKAGPVGPPGLGFPGPPG---ERGHPGVPGHPGVRGPDGLKGQKGDTISC 668

Query: 468  ---YPGQ---PGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE---PGRDGDKGDRG 518
               YPG+   PG DG PG +G  G  G PG  G  G +G PG  G    PG  G +GD G
Sbjct: 669  NVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMG 728

Query: 519  LPGFPGLHGM-----PGSKGEMGAKGDKGSPG--FYGKKGAKGEKGNAGFPGLPGPAGEP 571
             PGF G  G      PG  G  G  G KG PG   +G  G  G++G +G PG+ GP G+P
Sbjct: 729  DPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDP 788

Query: 572  GRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKK 631
            G  G +G  G PGF    G  G  G++G  G PG+P               GPPG   ++
Sbjct: 789  GCPGAEGPAGIPGF---LGLKGPKGREGHAGFPGVP---------------GPPGHSCER 830

Query: 632  GAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLP 691
            GAPG+P   G  G PG PG+PG+ G KG+PG  G PG +G+KG PG  G PG  G  GLP
Sbjct: 831  GAPGIP---GQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLP 887

Query: 692  GIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSK 751
            GI G  GD G  G  G +G +G  G  G PG++G  G  G  G +GE GE G+ G  G +
Sbjct: 888  GIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDR 947

Query: 752  GESGVDGLMGPAGPKG------QPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQL 805
            G  G  G +GP G +G      Q G PG  GPPG DG PG    +       T  ++ + 
Sbjct: 948  GLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKG------TPGMQGRR 1001

Query: 806  PVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGL------PGLPGRDGVPGLVGV 859
                + GR         + G  G PGPPGP GP G  GL      PGLPG  G PG  G 
Sbjct: 1002 G---EPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGP 1058

Query: 860  PGRPGVRGLK-------------GLPGRNGEKGSQG----FGYPGEQGPPGPPGPEGPPG 902
            PG  G+ G +             G PG  GE GS G    FG  GEQG PG  GP G PG
Sbjct: 1059 PGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPG 1118

Query: 903  ISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
              + GPPG  G PG  GDHG PG++GQPG  G
Sbjct: 1119 --RPGPPGSSGPPGCPGDHGMPGLRGQPGEMG 1148



 Score =  342 bits (878), Expect = 8e-94
 Identities = 241/620 (38%), Positives = 279/620 (45%), Gaps = 163/620 (26%)

Query: 447 PPGKPGLQGPKGDPGLPGNPGYPGQ---------PGQDGKPGYQGIAGTPGVPGSPGIQG 497
           PPG PG QGP G  G PG  G  G+         PG  G  G +G  G PG PG  GI G
Sbjct: 66  PPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPG 125

Query: 498 ARGLPGYKGEPGRDGDKGDRGLPGFPGLHGM---------PGSKGE-------------- 534
             G PG +G+PG  G  G RG PGFPG  G          PG KGE              
Sbjct: 126 HPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGI 185

Query: 535 MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSP--GFKGEAGSP 592
            G +GD G PG  G  GA G  G  G+PG PG  G PG+ G+ GL G+P  G KG+ G P
Sbjct: 186 QGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDP 245

Query: 593 GAPGQDGT---------------RGEPGIPGFPGNRGL---MGQKGEIGPPGQQGKKGAP 634
           G  GQ G+               +GE GI G PG  GL    G+KGE G  G +G+KG P
Sbjct: 246 GEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG-IGAKGEKGIP 304

Query: 635 GMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYM------ 688
           G PG  G  GS G PG PG KG  G  G  G+ G  G KG+PG  G PG PG +      
Sbjct: 305 GFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLP 364

Query: 689 --------GLPGIQGKKGDKGNQGEKGIQGQKGE--------NGRQGIPGQQGIQGHHG- 731
                   G PG  G+ GD G  G  G+ G+ GE         G QG PG  G+ G  G 
Sbjct: 365 LKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGI 424

Query: 732 ------AKGERGEKGEPGVRGA---------------IGSKGESGVDGLMGP---AGPKG 767
                 A G+ G+ G PG+ GA               +G+ G  G+ G +GP    GPKG
Sbjct: 425 PGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKG 484

Query: 768 QPG-------DPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHC 820
           + G       +PGP GPPG  G PGR+ S+                              
Sbjct: 485 EKGNEGLCACEPGPMGPPGPPGLPGRQGSK----------------------------GD 516

Query: 821 LSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVG---------VPGRPGVRGLKGL 871
           L   G  G  G PGP G EGP GLPG  G  G PG  G         V G  G RG  G 
Sbjct: 517 LGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGP 576

Query: 872 PGRNGEKGSQG-FGYPGEQGPPGP--------------PGPEGPPGISKEGPPGDPGL-- 914
           PG  G+ GS G  G+ GE+G PGP              PGP GPPG  K GP G PGL  
Sbjct: 577 PGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPG--KAGPVGPPGLGF 634

Query: 915 PGKDGDHGKPGIQGQPGPPG 934
           PG  G+ G PG+ G PG  G
Sbjct: 635 PGPPGERGHPGVPGHPGVRG 654



 Score =  332 bits (850), Expect = 1e-90
 Identities = 228/558 (40%), Positives = 263/558 (47%), Gaps = 84/558 (15%)

Query: 412  PEQNNRETACEIPGFNGEC----LNG-PSDVGSTPAP-CICPPGKPG------LQGPKGD 459
            P +  +  A   PG  GE     ++G P D G   A   I PPG  G       +G  G+
Sbjct: 917  PGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGE 976

Query: 460  PGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGL 519
            PG PG+ G+PG+ G  G PG QG  G PG  G PG    RG PG KG+PG  G  G  G 
Sbjct: 977  PGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFH--RGEPGEKGQPGPPGPPGPPGS 1034

Query: 520  PGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFP----GLPGPAGEPG--- 572
             G  G  G PG  G+ G  G  G PGF G  GA+G KGN G P    G PGP GEPG   
Sbjct: 1035 TGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPG 1094

Query: 573  ---RHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQ-- 627
                 G  G  G PG +G  GSPG PG  G+ G PG PG  G  GL GQ GE+G PG   
Sbjct: 1095 CPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRG 1154

Query: 628  -QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGM-----PGASGLKGEPGATGS 681
             QG  G PG PG+ G +GSPG  G  G KG KG  G  G+     PG  G+ G  G  G 
Sbjct: 1155 LQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGD 1214

Query: 682  PGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI----PGQQGIQGHHGAKGERG 737
            PG PG +  PG +GKKG  G  G  G  G  G  GR       PG  G QG  G  G RG
Sbjct: 1215 PGSPG-ISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRG 1273

Query: 738  EKGEPGVRGAIGS-KGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFI--- 793
              G PG+ G++   +GE G  GL GP GP G PG PG +G PG DGK G++    F    
Sbjct: 1274 APGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQ 1333

Query: 794  ----------RQVCTDVIRAQLPVLLQSGR--------IRNCDHCLSQHGSPGIPGP--- 832
                       +        + P  L   R        + +C       G+PG+ GP   
Sbjct: 1334 GPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGA 1393

Query: 833  ---PGPIGPEGP--RGLPGLPGR---DGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFG 884
               PG  GP GP  +G PGL GR   DGVPG  G PGR G  G                G
Sbjct: 1394 MGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGED--------------G 1439

Query: 885  YPGEQGPPGPPGPEGPPG 902
            YPG  GPPGP G  GP G
Sbjct: 1440 YPGGPGPPGPIGDPGPKG 1457



 Score =  323 bits (828), Expect = 5e-88
 Identities = 213/521 (40%), Positives = 249/521 (47%), Gaps = 97/521 (18%)

Query: 470 GQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRG---LPGFPGLH 526
           G  G  G PG QG  G  G PG  G+ G +G+ G +G PG  GDKGD+G   +PGFPGL 
Sbjct: 62  GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLD 121

Query: 527 GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586
           G+P         G  G PG  GK G  G  G+ G PG PG     G  G  G +G PG K
Sbjct: 122 GIP---------GHPGPPGPRGKPGMSGHNGSRGDPGFPGGR---GALGPGGPLGHPGEK 169

Query: 587 GEAGSP-----GAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG 641
           GE G+         G  G RG+PG+PG PG+ G  G  G  G PG+ G  G PG PG  G
Sbjct: 170 GEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPG 229

Query: 642 SNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKG 701
             G+PG  G  G  G  GE G QG PG + L   P      GE G  G+PG+ G  G  G
Sbjct: 230 LKGNPG-VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288

Query: 702 NQGEKGIQGQKGENGRQGIPGQQGIQGHHGA------KGERGEKGEPGVRGAIGSKGESG 755
            +GE GI G KGE G  G PG +G  G +G+      KGE G  G+PG+ G IG KG+ G
Sbjct: 289 RKGESGI-GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPG 347

Query: 756 VDGLMGPAGP--------KGQPGDP------------GPQGPPGLDGKPGREFSEQFIRQ 795
             G  GP G         KG PGDP            GP GPPGL G+PG         +
Sbjct: 348 NRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPG---------E 398

Query: 796 VCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIG-PEGPRGLPGLPGRDGVP 854
            C  +I    P                  G PG+PG PG  G P  P   PG PG+ G P
Sbjct: 399 ACAGMIGPPGP-----------------QGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSP 441

Query: 855 GLVGVPGRPGVRGLK------GLPGRNGEKGSQGFGYPGEQGP-------------PGPP 895
           GL G PG  G+ G        G PG  G KG    G PG +GP             PGP 
Sbjct: 442 GLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGK--VGPPGGRGPKGEKGNEGLCACEPGPM 499

Query: 896 GPEGPPGI-SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
           GP GPPG+  ++G  GD GLPG  G  G PG  G  GPPG+
Sbjct: 500 GPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGL 540



 Score =  226 bits (576), Expect = 8e-59
 Identities = 146/363 (40%), Positives = 175/363 (48%), Gaps = 54/363 (14%)

Query: 597 QDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKG 656
           + G+RG PG PG  G  G +G  G IG  G++G +G  G PG  G  G  G  G PG  G
Sbjct: 60  EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPG 119

Query: 657 SKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQ----- 711
             G PG  G PG  G  G  G  GS G+PG+ G  G  G  G  G+ GEKG +G      
Sbjct: 120 LDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFIL 179

Query: 712 ---KGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMG--PAGPK 766
              KG  G +G PG  G+ G  GA G  G  G PG  G +G  G+ G  GL G    G K
Sbjct: 180 GAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVK 239

Query: 767 GQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQ--- 823
           GQ GDPG  G  G  G                       P LL    +   D CL +   
Sbjct: 240 GQMGDPGEVGQQGSPG-----------------------PTLL----VEPPDFCLYKGEK 272

Query: 824 -----HGSPGIPGPPG-----PIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPG 873
                 G  G+PGPPG      IG +G +G+PG PG  G PG  G PG PG++G  GL G
Sbjct: 273 GIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVG 332

Query: 874 RNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGP 932
             G  G  G  G PG +G PGPPG    P +  +GPPGDPG PG+   +G+ G  G PGP
Sbjct: 333 DPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGR---YGETGDVGPPGP 389

Query: 933 PGI 935
           PG+
Sbjct: 390 PGL 392



 Score =  224 bits (571), Expect = 3e-58
 Identities = 159/430 (36%), Positives = 185/430 (43%), Gaps = 88/430 (20%)

Query: 586 KGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS 645
           KG  G PG PG  G  G  G PG  G  G  G +G+ GPPG  G KG  G  G+ G  G 
Sbjct: 61  KGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGL 120

Query: 646 PGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ-- 703
            G PG PG  G +G+PG+ G  G+ G  G PG  G+ G  G +G PG   +KG+KGN   
Sbjct: 121 DGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPG---EKGEKGNSVF 177

Query: 704 ---GEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKG---EPGVRGAIGSKGESGVD 757
                KGIQG +G+ G  G+PG  G  G  G  G  GE G    PG  G  G KG  GV 
Sbjct: 178 ILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVG 237

Query: 758 --GLMGPAGPKGQPGDPGP------------QGPPGLDGKPGREFSEQFIRQVCTDVIRA 803
             G MG  G  GQ G PGP            +G  G+ G PG                  
Sbjct: 238 VKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGM----------------- 280

Query: 804 QLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRP 863
              V L     R  +  +   G  GIPG PGP G  G  G PG PG  G  GLVG PG  
Sbjct: 281 ---VGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLF 337

Query: 864 GVRGLKGLPGRNGEKGSQG---------------------FGYPGEQGPPGPPGPEGPPG 902
           G+ G KG PG  G  G  G                     +G  G+ GPPGPPG  G PG
Sbjct: 338 GLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPG 397

Query: 903 ------ISKEGPPGDPGLPG----------------KDGDHGKPGIQGQPGPPGICDPSL 940
                 I   GP G PGLPG                K G  G PG+ G PG  G+   S+
Sbjct: 398 EACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSV 457

Query: 941 CFSVIARRDP 950
            +  +    P
Sbjct: 458 IYCSVGNPGP 467



 Score =  199 bits (507), Expect = 8e-51
 Identities = 124/293 (42%), Positives = 148/293 (50%), Gaps = 29/293 (9%)

Query: 424  PGFNG-ECLNGPSDV-GSTPAPCICPPGKPGLQGPKGDPGLPGNPGY--PGQPGQDGKPG 479
            PG NG   L G     G++    + PPG  G+ G KG+ G PG+PG   PG  G+ G PG
Sbjct: 1174 PGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPG 1233

Query: 480  YQGIAGTPGVPGSPGIQGAR----GLPGYKGEPGRDGDKGDRGLPGFPGLH--------- 526
              G +G PG  G+ G         G PG +G PG DG +G  G PG PG           
Sbjct: 1234 PPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGD 1293

Query: 527  -GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGF 585
             G+PG  G  G  G  G  GF G  G  G+KG  GFPG  GP G PG  G+ GL G PG 
Sbjct: 1294 CGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGR 1353

Query: 586  KGEAGSPGAPGQDGTRGE----PGIPGFPGNRGLMGQKGEIGPPGQQGK-----KGAPGM 636
            KG  G PG  G+ G   +    P IPG PG  G+ G +G +G PG +G      KG PG+
Sbjct: 1354 KGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGL 1413

Query: 637  PGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMG 689
             G  G +G PG PG PG KG  GE G  G PG  G  G+PG  G    PGY+G
Sbjct: 1414 DGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGF--GPGYLG 1464



 Score =  163 bits (412), Expect = 8e-40
 Identities = 115/329 (34%), Positives = 141/329 (42%), Gaps = 72/329 (21%)

Query: 660 EPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQG 719
           E G +G PG  G +G  G  G+PG    +GL G +G +GD+G  G  G +G KG  G  G
Sbjct: 60  EKGSRGPPGPPGPQGPIGPLGAPGP---IGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPG 116

Query: 720 IPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPG 779
            PG  GI GH G  G RG+ G  G  G+ G  G  G  G +GP GP G PG+ G +G   
Sbjct: 117 FPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKG--- 173

Query: 780 LDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPE 839
                    +  FI                  G ++         G PG+PG PG  G  
Sbjct: 174 ---------NSVFIL-----------------GAVKGIQ---GDRGDPGLPGLPGSWGAG 204

Query: 840 GPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPG-------------------------- 873
           GP G  G PG    PGLVG PG+PG  GLKG PG                          
Sbjct: 205 GPAGPTGYPGE---PGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVE 261

Query: 874 ------RNGEKGSQGF-GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGI 926
                   GEKG +G  G  G  GPPG  G  G     ++G PG PG  G  G +G PG 
Sbjct: 262 PPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGF 321

Query: 927 QGQPGPPGIC-DPSLCFSVIARRDPFRKG 954
            G  G  G+  DP L   +  + DP  +G
Sbjct: 322 PGLKGELGLVGDPGLFGLIGPKGDPGNRG 350



 Score =  108 bits (269), Expect = 3e-23
 Identities = 75/209 (35%), Positives = 84/209 (40%), Gaps = 63/209 (30%)

Query: 748 IGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPV 807
           +  KG  G  G  GP GP G  G P   GP GL G+ G                      
Sbjct: 58  VPEKGSRGPPGPPGPQGPIGPLGAP---GPIGLSGEKG---------------------- 92

Query: 808 LLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRG 867
                            G  G PG  G  G +GP G+PG PG DG+P   G PG PG RG
Sbjct: 93  ---------------MRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIP---GHPGPPGPRG 134

Query: 868 LKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKE------------------GPP 909
             G+ G NG +G  GF  PG +G  GP GP G PG   E                  G P
Sbjct: 135 KPGMSGHNGSRGDPGF--PGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDP 192

Query: 910 GDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
           G PGLPG  G  G  G  G PG PG+  P
Sbjct: 193 GLPGLPGSWGAGGPAGPTGYPGEPGLVGP 221



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 51/120 (42%), Positives = 64/120 (53%), Gaps = 10/120 (8%)

Query: 412  PEQNNRETACEIPGFNGECLNGPSDVGSTPA-PCICPPGKPGLQGPKGDPGLPG-----N 465
            P    R+    +PG  GE    P+DV   P  P +  PG PG++GP+G  GLPG      
Sbjct: 1348 PGPPGRKGPTGLPGPRGEP-GPPADVDDCPRIPGL--PGAPGMRGPEGAMGLPGMRGPSG 1404

Query: 466  PGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGL-PGFPG 524
            PG  G+PG DG+ G  G+ G+PG PG  G  G  G PG  G PG  GD G +G  PG+ G
Sbjct: 1405 PGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLG 1464


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score =  391 bits (1005), Expect = e-108
 Identities = 231/543 (42%), Positives = 269/543 (49%), Gaps = 60/543 (11%)

Query: 423 IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQG------PKGDPGLPGNPGYPGQPGQDG 476
           IPG  G     P   G+   P   P G PG QG      PKG  G PG  G+ G+ G  G
Sbjct: 415 IPGAKGSA-GAPGIAGAPGFPG--PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 471

Query: 477 KPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536
           +PG  G  G PG  G  G +GARG PG  G  G  G++G  G  GFPG  G+ G KG   
Sbjct: 472 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG--- 528

Query: 537 AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP---AGEPGRHGKDGLMGSPGFKGEAGSPG 593
           A G++G  G  G KGA G+ G  G PGLPG     G PG  G  G +G  G  GE G PG
Sbjct: 529 APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 588

Query: 594 APGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPG 653
            PG  G RG+PG+ GFPG +   G  GE G  G++G  GAPG+ GL G +G  G  G PG
Sbjct: 589 PPGPQGARGQPGVMGFPGPK---GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645

Query: 654 SKGSKGEPGIQGMPGASGLKGEPGATGSPGE---------PGYMGLPGIQGKKGDKGNQG 704
             G  GE G QG PG SG +G PG  G PGE         PG  G PG+ G +G++G  G
Sbjct: 646 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 705

Query: 705 EKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAG 764
           E+G  G +G  G +G+PG  G  G  GA G  G  G  G  G  G  GE G  G+ GP G
Sbjct: 706 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765

Query: 765 PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQH 824
            +G  G+ GP+G PG DG  G            T  I    P                 +
Sbjct: 766 DRGDVGEKGPEGAPGKDGGRG-----------LTGPIGPPGPA--------------GAN 800

Query: 825 GSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-F 883
           G  G  GPPGP G  G RG PG  G  G PG  G  G PG  G  G  G  GE G +G  
Sbjct: 801 GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 860

Query: 884 GYPGEQGPPGPPGPEGPPGIS-------KEGPPGDPGLPGKDGDHGKPGIQGQPGPPGIC 936
           G PG QGP G PGP+GP G++        +GPPG  G PG  G  G PG  G PGPPG  
Sbjct: 861 GAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP 920

Query: 937 DPS 939
            PS
Sbjct: 921 GPS 923



 Score =  389 bits (998), Expect = e-108
 Identities = 249/632 (39%), Positives = 293/632 (46%), Gaps = 126/632 (19%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            +PG +GE     +     P P   P G+ G QG  G  G  G PG PG PG+ GKPG QG
Sbjct: 631  LPGKDGE-----TGAAGPPGPA-GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG 684

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGF-------------------- 522
            + G  G PG  G +G RG PG +G PG  G +G RGLPG                     
Sbjct: 685  VPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG 744

Query: 523  -PGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEP---GRHGKDG 578
             PGL GMPG +G  G  G KG  G  G+KG +G  G  G  GL GP G P   G +G+ G
Sbjct: 745  PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG 804

Query: 579  LMGSPGFKGEAGSPGAPGQDGTRGEP------------GIPGFPGNRGLMGQKGEIGPPG 626
             +G PG  G AG+ GAPG+ G  G P            G PG  G +G  GQKG+ G PG
Sbjct: 805  EVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG 864

Query: 627  QQGKKGAP---------GMPGLMGSNGSPGQPGTPGS------KGSKGEPGIQGMPGASG 671
             QG  GAP         G  G  G+ G PG  G PG+       GS G PG  G PG SG
Sbjct: 865  PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG 924

Query: 672  LKGEPGATGSPGEPGYMGLPGIQ---GKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQG 728
              G  GA G  G PG  G PG+Q   G  G+KG  G+ G  G +G  G QG+ GQ+GI G
Sbjct: 925  KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG 984

Query: 729  HHGAKGER------GEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDG 782
              G +GER      G  GEPG +GA G+ G+ G  G +GP G  G  G+PG +G PG DG
Sbjct: 985  LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG 1044

Query: 783  KPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPP--------- 833
             PGR+                       +  ++         G+PG PGPP         
Sbjct: 1045 PPGRD----------------------GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1082

Query: 834  ------------GPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLK---------GLP 872
                        GP+GP GP G  G+ G  G  G  G  G PG RGLK         GLP
Sbjct: 1083 GKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP 1142

Query: 873  GRNGEKGSQGFGYP-GEQGPPGPPGPEGPPGISKE-------GPPGDPGLPGKDGDHGKP 924
            G  G  G QG   P G  GP GPPGP GP G           GPPG  G  G+ G  G P
Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1202

Query: 925  GIQGQPGPPGICDPSLCFSVIARRDPFRKGPN 956
            G  G PGPPG   P +  S  A   P  KGP+
Sbjct: 1203 GNPGPPGPPGPPGPGIDMSAFAGLGPREKGPD 1234



 Score =  387 bits (993), Expect = e-107
 Identities = 242/570 (42%), Positives = 277/570 (48%), Gaps = 87/570 (15%)

Query: 424  PGFNGEC-LNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            PG  G   L GP      P      PG+PGL G +G  G PG+ G  G+ G  G PG  G
Sbjct: 530  PGERGPSGLAGPKGANGDPGR----PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 585

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKG 542
              G PG  G+ G  G  G PG KG  G  G  G++GLPG PGL G+PG  GE GA G  G
Sbjct: 586  RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645

Query: 543  SPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSP---------------GFKG 587
              G  G++G +G  G +GF GLPGP G PG  GK G  G P               GF G
Sbjct: 646  PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 705

Query: 588  EAGSPGAPGQDGTRGEPGIP------------------------GFPGNR---GLMGQKG 620
            E GSPGA G  G RG PG P                        G PG R   G+ G KG
Sbjct: 706  ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765

Query: 621  EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE---PGIQGMPGASGLKGEPG 677
            + G  G++G +GAPG  G  G  G  G PG  G+ G KGE   PG  G  GA G  GE G
Sbjct: 766  DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 825

Query: 678  ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             TG PG  G+ G PG  G+ G KG QGE    GQKG+    G PG QG  G  G +G  G
Sbjct: 826  ETGPPGPAGFAGPPGADGQPGAKGEQGE---AGQKGD---AGAPGPQGPSGAPGPQGPTG 879

Query: 738  EKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVC 797
              G  G RGA G  G +G  G  G  GP G  G+PGP GPPG  GK G + +    R   
Sbjct: 880  VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA----RGDS 935

Query: 798  TDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLV 857
                RA  P L                G PG  G PG  GP G  G PG  G  G  G+V
Sbjct: 936  GPPGRAGEPGL------------QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 983

Query: 858  GVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGIS-------KEGPPG 910
            G+PG+ G RG  GLPG +GE G Q  G PG  G  GPPGP GPPG++       +EG PG
Sbjct: 984  GLPGQRGERGFPGLPGPSGEPGKQ--GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 1041

Query: 911  DPGLPGKD------GDHGKPGIQGQPGPPG 934
              G PG+D      GD G+ G  G PG PG
Sbjct: 1042 ADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1071



 Score =  385 bits (989), Expect = e-106
 Identities = 231/551 (41%), Positives = 266/551 (48%), Gaps = 76/551 (13%)

Query: 425 GFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIA 484
           GF+ +       V   P   + P G PG  G  G  G  GNPG PG+PG  G  G +G  
Sbjct: 186 GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPP 245

Query: 485 GTPGVPGS---------------PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMP 529
           G PG PG                PG QGARG PG  G PG  G +G  GL G  G  G P
Sbjct: 246 GPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAP 305

Query: 530 GSKGEMGAKGDKGSPGFYGKKGAKGE------------KGNAGFPGLPGPAGEPGRHGKD 577
           G KGE G+ G+ GSPG  G +G  GE            +GN G PG  GP G  G  G  
Sbjct: 306 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 365

Query: 578 GLMGSPGFKGEAGSPGAPGQDGT---RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAP 634
           G  G+PG KGEAG  GA G +G    RGEPG PG PG  G  G  G  G PG +G  GAP
Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 425

Query: 635 GM---PGLMGSNGSPGQPGTP---GSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYM 688
           G+   PG  G  G PG  G     G KG  GEPGI G  G  G KGEPG  G  G PG  
Sbjct: 426 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 485

Query: 689 GLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAI 748
           G  G +G +G+ G  G  G  G++G  G +G PGQ G+ G  GA GERG  G  G +GA 
Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 545

Query: 749 GSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVL 808
           G  G  G  GL G  G  G+PGD GPQG  G  G PG +                     
Sbjct: 546 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED--------------------- 584

Query: 809 LQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGL 868
                           G PG PGP G  G  G  G PG  G +G PG  G  G PG  GL
Sbjct: 585 ----------------GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 628

Query: 869 KGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISK-EGPPGDPGLPGKDGDHGKPGIQ 927
           +GLPG++GE G+   G PG  GP G  G +G PG S  +G PG PG PG+ G  G  G+ 
Sbjct: 629 RGLPGKDGETGAA--GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 686

Query: 928 GQPGPPGICDP 938
           G+ G PG+  P
Sbjct: 687 GEAGAPGLVGP 697



 Score =  382 bits (981), Expect = e-106
 Identities = 234/556 (42%), Positives = 268/556 (48%), Gaps = 57/556 (10%)

Query: 433 GPSDVGSTPAPCICP-----------PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQ 481
           GP      P P   P           PG+PG+ GP G  G PG PG PG  G+ GKPG  
Sbjct: 204 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 263

Query: 482 GIAGTPGVPGSPGIQGARGLPGYKGE---PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAK 538
           G  G PG  G+ G  G  GLPG KG    PG DG KG+ G PG  G  G PG  G  G  
Sbjct: 264 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 323

Query: 539 GDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGK---DGLMGSPGFKGEAGSPGAP 595
           G +G PG  G+ G  G  G  G  G PGPAG PG  G     G  G+PG KGEAG  GA 
Sbjct: 324 GPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 383

Query: 596 GQDGT---RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM---PGLMGSNGSPGQP 649
           G +G    RGEPG PG PG  G  G  G  G PG +G  GAPG+   PG  G  G PG  
Sbjct: 384 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 443

Query: 650 GTPGS---KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEK 706
           G  G    KG  GEPGI G  G  G KGEPG  G  G PG  G  G +G +G+ G  G  
Sbjct: 444 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503

Query: 707 GIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKG---------------EPGVRGAIGSK 751
           G  G++G  G +G PGQ G+ G  GA GERG  G               EPG+ GA G  
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563

Query: 752 GESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQF--IRQVCTDVIRAQLPVLL 809
           G  G  G  G  GP G PG+ G  GPPG  G  G+     F   +    +  +A    L 
Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP 623

Query: 810 QSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLK 869
            +  +R       + G  G  GPPGP GP G RG  G PG  G  GL G PG PG  G  
Sbjct: 624 GAPGLRGLP---GKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 680

Query: 870 GLPGRNGEKGSQGF-------GYPGEQGPPGPPGPEGPPGI----SKEGPPGDPGLPGKD 918
           G  G  GE G+ G        G+PGE+G PG  G +GP G+      +GP G  G  G  
Sbjct: 681 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 740

Query: 919 GDHGKPGIQGQPGPPG 934
           G  G PG+QG PG  G
Sbjct: 741 GAQGPPGLQGMPGERG 756



 Score =  380 bits (976), Expect = e-105
 Identities = 247/606 (40%), Positives = 295/606 (48%), Gaps = 120/606 (19%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK------ 477
           PG +GE    P   G        PPG  G +G  G PGLPG  G+ G PG DG       
Sbjct: 251 PGDDGEA-GKPGKAGERG-----PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304

Query: 478 PGYQGIAGTPGVPGSPGIQGARGLPGYKGEPG---------RDGDKGDRGLPGFPGLHGM 528
           PG +G +G+PG  GSPG  G RGLPG +G  G          DG  G  G PG  G  G 
Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 364

Query: 529 PGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGE 588
           PG  G  GAKG+ G  G  G +GA+G +G  G PG PGPAG  G  G DG+ G+ G  G 
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424

Query: 589 AGSPGAPGQDGTR------------------GEPGIPGFPGNRGLMGQ------KGEIGP 624
            G  GAPG  G R                  GEPGI GF G +G  G+      +G  GP
Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 484

Query: 625 PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA------SGLKGEPGA 678
            G++GK+GA G PG +G  G PG+ G PG++G  G+ G+ G  GA      SGL G  GA
Sbjct: 485 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 544

Query: 679 TGSPGEPGYMGLP---GIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGH------ 729
            G PG PG  GLP   G+ G+ GD G QG+ G  G  GE+GR G PG QG +G       
Sbjct: 545 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604

Query: 730 ---HGAKGERGEKGE------PGVRGAIGSKGESGVDGLMGPAGPKGQPGD--------- 771
               GA GE G+ GE      PG+RG  G  GE+G  G  GPAGP G+ G+         
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664

Query: 772 ---PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPG 828
              PGP GPPG  GKPG +               A  P L+             + G PG
Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPG----------EAGAPGLVGP---------RGERGFPG 705

Query: 829 IPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYP-- 886
             G PG  G +GPRGLPG PG DG  G  G  G PG +G  GL G  GE+G+ G   P  
Sbjct: 706 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765

Query: 887 -----GEQGPPGPP---------GPEGPPGIS----KEGPPGDPGLPGKDGDHGKPGIQG 928
                GE+GP G P         GP GPPG +    ++G  G PG  G  G  G PG +G
Sbjct: 766 DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 825

Query: 929 QPGPPG 934
           + GPPG
Sbjct: 826 ETGPPG 831



 Score =  372 bits (956), Expect = e-103
 Identities = 216/522 (41%), Positives = 261/522 (50%), Gaps = 75/522 (14%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
            P G PG +GP G  G  G  G PG+PG+ G PG +G+ G PG  G  G  G  G PG  G
Sbjct: 526  PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 585

Query: 507  EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
             PG  G +G RG PG  G  G  G+ GE G  G+KG PG  G +G  G+ G  G  G PG
Sbjct: 586  RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645

Query: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPG 626
            PAG  G  G+ G  G  GF+G  G PG PG+ G  G+ G+PG  G  GL+G +GE G PG
Sbjct: 646  PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 705

Query: 627  QQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPG 686
            ++G  GA G+ G  G  G+PG  G  G+ G  G PG QG PG  G+ GE GA G      
Sbjct: 706  ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG------ 759

Query: 687  YMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRG 746
                  I G KGD+G+ GEKG +G  G++G +G+ G  G  G  GA GE+GE G PG  G
Sbjct: 760  ------IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 813

Query: 747  AIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLP 806
            + G++G  G  G  GP GP G  G PG  G PG  G+ G                     
Sbjct: 814  SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEA------------------- 854

Query: 807  VLLQSGRIRNCDHCLSQHGSPGIPGPPGPI---GPEGP---------RGLPGLPGRDGVP 854
                            Q G  G PGP GP    GP+GP         RG  G PG  G P
Sbjct: 855  ---------------GQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899

Query: 855  GLVGVPGRPGVRGLKGLP------GRNGEKGSQG-------FGYPGEQGPPGPPGPEGPP 901
            G  G  G PG  G  G P      G++G KG++G        G PG QGP GPPG +G P
Sbjct: 900  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959

Query: 902  G----ISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
            G       EGPPG  GL G+ G  G PG +G+ G PG+  PS
Sbjct: 960  GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001



 Score =  370 bits (951), Expect = e-102
 Identities = 220/527 (41%), Positives = 255/527 (48%), Gaps = 82/527 (15%)

Query: 449 GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGY---------------------------- 480
           G PG +G  G+PG PGNPG PG PG  G PG                             
Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 203

Query: 481 --QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAK 538
              G  G PG  G+PG QG +G PG  GEPG  G  G RG PG PG  G  G  G+ G  
Sbjct: 204 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 263

Query: 539 GDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQD 598
           G++G PG    +GA+G  G  G PG+ G  G PG  G  G  G+PG KGE+GSPG   ++
Sbjct: 264 GERGPPG---PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG---EN 317

Query: 599 GTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSK 658
           G+ G  G  G PG RG  G  G  G  G  G+ G  G PG +G  G PG PG PG+KG  
Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 377

Query: 659 GEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQ 718
           G  G +G  GA G +GEPG  GSPG  G  G PG  G  G KG+ G  GI G  G  G +
Sbjct: 378 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437

Query: 719 GIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGP---------KGQP 769
           G PG QG  G  G KG+ GE G  G +G  G KGE G  G  G  GP         +G+P
Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 497

Query: 770 GDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI 829
           G  GP GPPG  G PG                                       G  G+
Sbjct: 498 GGVGPIGPPGERGAPGNR----------------------------------GFPGQDGL 523

Query: 830 PGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGE 888
            GP G  G  GP GL G  G +G PG  G PG PG RGL G PG  G +G  G  G PGE
Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583

Query: 889 QGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
            G PGPPGP+G  G  + G  G PG  G +G+ GK G +G PG PG+
Sbjct: 584 DGRPGPPGPQGARG--QPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 628



 Score =  321 bits (822), Expect = 2e-87
 Identities = 197/479 (41%), Positives = 236/479 (49%), Gaps = 69/479 (14%)

Query: 445  ICPPGKPGLQGPKGDPGLPGNPGY------PGQPGQDGKPGYQGIAGTPGVPGSPGIQGA 498
            I PPG  G  G KG+ G PG  G       PG+ G+ G PG  G AG PG  G PG +G 
Sbjct: 791  IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850

Query: 499  RGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGN 558
            +G  G KG+ G  G +G  G PG  G  G+ G KG  GA+G  G+ GF G  G  G  G+
Sbjct: 851  QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 910

Query: 559  AGFPGLPGPAGEPGRHGKDGLMGS---------PGFKGEAGSPGAPGQDGTRGEPGIPGF 609
             G PG PGP G  G+ G  G  G          PG +G AG PG  G+ G  G  G  G 
Sbjct: 911  NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP 970

Query: 610  PGNRGLMGQKGEIGPPGQQGKKGAPGMPG------------LMGSNGSPGQPGTPGSKGS 657
            PG +GL GQ+G +G PGQ+G++G PG+PG              G  G PG  G PG  G 
Sbjct: 971  PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030

Query: 658  KGEPGIQGMPGA---------SGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
             GEPG +G PGA         +G+KG+ G TG+ G PG  G PG  G  G  G QG++G 
Sbjct: 1031 AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090

Query: 709  QGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQ 768
             G +G  G  G  G +GIQG  G +G++GE GEPG RG  G +G +G+ GL GP GP G 
Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1150

Query: 769  PGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPG 828
             G  GP GP G  G PG                    PV   SG+          +G PG
Sbjct: 1151 QGASGPAGPSGPRGPPG--------------------PVG-PSGKD-------GANGIPG 1182

Query: 829  IPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGV--RGLKGLPGRNGEKGSQGFGY 885
              GPPGP G  G  G  G PG  G PG  G PG PG+      GL  R  EKG     Y
Sbjct: 1183 PIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG-PGIDMSAFAGLGPR--EKGPDPLQY 1238



 Score =  311 bits (796), Expect = 2e-84
 Identities = 199/500 (39%), Positives = 231/500 (46%), Gaps = 86/500 (17%)

Query: 498 ARGLPGYKGEPGRDGD----KGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAK 553
           A G PG KG+ G  GD     G +G PG  G  G  G +G+ G KG+KG+PG  G+ G  
Sbjct: 96  ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 554 GEKGNAGFPGLPGPAGEPGRHGK---------------------DGLMGSPGFKGEAGSP 592
           G  GN G PG PGP G PG  G                       G MG  G +G  G  
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 593 GAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQG---------KKGAPGMPGLMGSN 643
           GAPG  G +G PG PG PG  G MG +G  GPPG+ G         K G  G PG  G+ 
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 275

Query: 644 GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ 703
           G PG PG PG KG +G PG+    GA G  G PG  G  G PG  G PG  G +G  G +
Sbjct: 276 GFPGTPGLPGVKGHRGYPGLD---GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 332

Query: 704 GEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPA 763
           G  G  G  G  G  G PG  G  G  G  G  G  G PG +G  G  G  G +G  GP 
Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392

Query: 764 GPKGQPGDPGP---QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHC 820
           G  G PG PGP    G PG DG PG + S             A  P +            
Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGS-------------AGAPGIA----------- 428

Query: 821 LSQHGSPGIPGPPGPIGPE------GPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGR 874
               G+PG PGP GP GP+      GP+G  G PG  G  G  G  G PG  G +G PG 
Sbjct: 429 ----GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 484

Query: 875 NGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            GE+G +     G +G PG  GP GPPG  + G PG+ G PG+DG  G  G  G+ GP G
Sbjct: 485 AGEEGKR-----GARGEPGGVGPIGPPG--ERGAPGNRGFPGQDGLAGPKGAPGERGPSG 537

Query: 935 ICDPSLCFSVIARRDPFRKG 954
           +  P       A  DP R G
Sbjct: 538 LAGPK-----GANGDPGRPG 552



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 38/83 (45%), Positives = 43/83 (51%), Gaps = 11/83 (13%)

Query: 856 LVGVPGRPGVRGLKGLPGR----NGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGD 911
           L    G+PG +G KG PG      G KG      PG QGP G  GP G  G   +G  G 
Sbjct: 93  LATASGQPGPKGQKGEPGDIKDIVGPKGP-----PGPQGPAGEQGPRGDRG--DKGEKGA 145

Query: 912 PGLPGKDGDHGKPGIQGQPGPPG 934
           PG  G+DG+ G PG  G PGPPG
Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPPG 168


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  391 bits (1005), Expect = e-108
 Identities = 231/543 (42%), Positives = 269/543 (49%), Gaps = 60/543 (11%)

Query: 423 IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQG------PKGDPGLPGNPGYPGQPGQDG 476
           IPG  G     P   G+   P   P G PG QG      PKG  G PG  G+ G+ G  G
Sbjct: 346 IPGAKGSA-GAPGIAGAPGFPG--PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 402

Query: 477 KPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536
           +PG  G  G PG  G  G +GARG PG  G  G  G++G  G  GFPG  G+ G KG   
Sbjct: 403 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG--- 459

Query: 537 AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP---AGEPGRHGKDGLMGSPGFKGEAGSPG 593
           A G++G  G  G KGA G+ G  G PGLPG     G PG  G  G +G  G  GE G PG
Sbjct: 460 APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 519

Query: 594 APGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPG 653
            PG  G RG+PG+ GFPG +   G  GE G  G++G  GAPG+ GL G +G  G  G PG
Sbjct: 520 PPGPQGARGQPGVMGFPGPK---GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576

Query: 654 SKGSKGEPGIQGMPGASGLKGEPGATGSPGE---------PGYMGLPGIQGKKGDKGNQG 704
             G  GE G QG PG SG +G PG  G PGE         PG  G PG+ G +G++G  G
Sbjct: 577 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 636

Query: 705 EKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAG 764
           E+G  G +G  G +G+PG  G  G  GA G  G  G  G  G  G  GE G  G+ GP G
Sbjct: 637 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696

Query: 765 PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQH 824
            +G  G+ GP+G PG DG  G            T  I    P                 +
Sbjct: 697 DRGDVGEKGPEGAPGKDGGRG-----------LTGPIGPPGPA--------------GAN 731

Query: 825 GSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-F 883
           G  G  GPPGP G  G RG PG  G  G PG  G  G PG  G  G  G  GE G +G  
Sbjct: 732 GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 791

Query: 884 GYPGEQGPPGPPGPEGPPGIS-------KEGPPGDPGLPGKDGDHGKPGIQGQPGPPGIC 936
           G PG QGP G PGP+GP G++        +GPPG  G PG  G  G PG  G PGPPG  
Sbjct: 792 GAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP 851

Query: 937 DPS 939
            PS
Sbjct: 852 GPS 854



 Score =  389 bits (998), Expect = e-108
 Identities = 249/632 (39%), Positives = 293/632 (46%), Gaps = 126/632 (19%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            +PG +GE     +     P P   P G+ G QG  G  G  G PG PG PG+ GKPG QG
Sbjct: 562  LPGKDGE-----TGAAGPPGPA-GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG 615

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGF-------------------- 522
            + G  G PG  G +G RG PG +G PG  G +G RGLPG                     
Sbjct: 616  VPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG 675

Query: 523  -PGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEP---GRHGKDG 578
             PGL GMPG +G  G  G KG  G  G+KG +G  G  G  GL GP G P   G +G+ G
Sbjct: 676  PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG 735

Query: 579  LMGSPGFKGEAGSPGAPGQDGTRGEP------------GIPGFPGNRGLMGQKGEIGPPG 626
             +G PG  G AG+ GAPG+ G  G P            G PG  G +G  GQKG+ G PG
Sbjct: 736  EVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG 795

Query: 627  QQGKKGAP---------GMPGLMGSNGSPGQPGTPGS------KGSKGEPGIQGMPGASG 671
             QG  GAP         G  G  G+ G PG  G PG+       GS G PG  G PG SG
Sbjct: 796  PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG 855

Query: 672  LKGEPGATGSPGEPGYMGLPGIQ---GKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQG 728
              G  GA G  G PG  G PG+Q   G  G+KG  G+ G  G +G  G QG+ GQ+GI G
Sbjct: 856  KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG 915

Query: 729  HHGAKGER------GEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDG 782
              G +GER      G  GEPG +GA G+ G+ G  G +GP G  G  G+PG +G PG DG
Sbjct: 916  LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG 975

Query: 783  KPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPP--------- 833
             PGR+                       +  ++         G+PG PGPP         
Sbjct: 976  PPGRD----------------------GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1013

Query: 834  ------------GPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLK---------GLP 872
                        GP+GP GP G  G+ G  G  G  G  G PG RGLK         GLP
Sbjct: 1014 GKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP 1073

Query: 873  GRNGEKGSQGFGYP-GEQGPPGPPGPEGPPGISKE-------GPPGDPGLPGKDGDHGKP 924
            G  G  G QG   P G  GP GPPGP GP G           GPPG  G  G+ G  G P
Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1133

Query: 925  GIQGQPGPPGICDPSLCFSVIARRDPFRKGPN 956
            G  G PGPPG   P +  S  A   P  KGP+
Sbjct: 1134 GNPGPPGPPGPPGPGIDMSAFAGLGPREKGPD 1165



 Score =  387 bits (993), Expect = e-107
 Identities = 242/570 (42%), Positives = 277/570 (48%), Gaps = 87/570 (15%)

Query: 424  PGFNGEC-LNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            PG  G   L GP      P      PG+PGL G +G  G PG+ G  G+ G  G PG  G
Sbjct: 461  PGERGPSGLAGPKGANGDPGR----PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 516

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKG 542
              G PG  G+ G  G  G PG KG  G  G  G++GLPG PGL G+PG  GE GA G  G
Sbjct: 517  RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576

Query: 543  SPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPG---------------FKG 587
              G  G++G +G  G +GF GLPGP G PG  GK G  G PG               F G
Sbjct: 577  PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 636

Query: 588  EAGSPGAPGQDGTRGEPGIP------------------------GFPGNR---GLMGQKG 620
            E GSPGA G  G RG PG P                        G PG R   G+ G KG
Sbjct: 637  ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696

Query: 621  EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE---PGIQGMPGASGLKGEPG 677
            + G  G++G +GAPG  G  G  G  G PG  G+ G KGE   PG  G  GA G  GE G
Sbjct: 697  DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 756

Query: 678  ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
             TG PG  G+ G PG  G+ G KG QGE    GQKG+    G PG QG  G  G +G  G
Sbjct: 757  ETGPPGPAGFAGPPGADGQPGAKGEQGE---AGQKGD---AGAPGPQGPSGAPGPQGPTG 810

Query: 738  EKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVC 797
              G  G RGA G  G +G  G  G  GP G  G+PGP GPPG  GK G + +    R   
Sbjct: 811  VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA----RGDS 866

Query: 798  TDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLV 857
                RA  P L                G PG  G PG  GP G  G PG  G  G  G+V
Sbjct: 867  GPPGRAGEPGL------------QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 914

Query: 858  GVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGIS-------KEGPPG 910
            G+PG+ G RG  GLPG +GE G Q  G PG  G  GPPGP GPPG++       +EG PG
Sbjct: 915  GLPGQRGERGFPGLPGPSGEPGKQ--GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 972

Query: 911  DPGLPGKD------GDHGKPGIQGQPGPPG 934
              G PG+D      GD G+ G  G PG PG
Sbjct: 973  ADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1002



 Score =  385 bits (989), Expect = e-106
 Identities = 231/551 (41%), Positives = 266/551 (48%), Gaps = 76/551 (13%)

Query: 425 GFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIA 484
           GF+ +       V   P   + P G PG  G  G  G  GNPG PG+PG  G  G +G  
Sbjct: 117 GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPP 176

Query: 485 GTPGVPGS---------------PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMP 529
           G PG PG                PG QGARG PG  G PG  G +G  GL G  G  G P
Sbjct: 177 GPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAP 236

Query: 530 GSKGEMGAKGDKGSPGFYGKKGAKGE------------KGNAGFPGLPGPAGEPGRHGKD 577
           G KGE G+ G+ GSPG  G +G  GE            +GN G PG  GP G  G  G  
Sbjct: 237 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 296

Query: 578 GLMGSPGFKGEAGSPGAPGQDGT---RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAP 634
           G  G+PG KGEAG  GA G +G    RGEPG PG PG  G  G  G  G PG +G  GAP
Sbjct: 297 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 356

Query: 635 GM---PGLMGSNGSPGQPGTP---GSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYM 688
           G+   PG  G  G PG  G     G KG  GEPGI G  G  G KGEPG  G  G PG  
Sbjct: 357 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416

Query: 689 GLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAI 748
           G  G +G +G+ G  G  G  G++G  G +G PGQ G+ G  GA GERG  G  G +GA 
Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 476

Query: 749 GSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVL 808
           G  G  G  GL G  G  G+PGD GPQG  G  G PG +                     
Sbjct: 477 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED--------------------- 515

Query: 809 LQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGL 868
                           G PG PGP G  G  G  G PG  G +G PG  G  G PG  GL
Sbjct: 516 ----------------GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 559

Query: 869 KGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISK-EGPPGDPGLPGKDGDHGKPGIQ 927
           +GLPG++GE G+   G PG  GP G  G +G PG S  +G PG PG PG+ G  G  G+ 
Sbjct: 560 RGLPGKDGETGAA--GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 617

Query: 928 GQPGPPGICDP 938
           G+ G PG+  P
Sbjct: 618 GEAGAPGLVGP 628



 Score =  382 bits (981), Expect = e-106
 Identities = 234/556 (42%), Positives = 268/556 (48%), Gaps = 57/556 (10%)

Query: 433 GPSDVGSTPAPCICP-----------PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQ 481
           GP      P P   P           PG+PG+ GP G  G PG PG PG  G+ GKPG  
Sbjct: 135 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 194

Query: 482 GIAGTPGVPGSPGIQGARGLPGYKGE---PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAK 538
           G  G PG  G+ G  G  GLPG KG    PG DG KG+ G PG  G  G PG  G  G  
Sbjct: 195 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 254

Query: 539 GDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGK---DGLMGSPGFKGEAGSPGAP 595
           G +G PG  G+ G  G  G  G  G PGPAG PG  G     G  G+PG KGEAG  GA 
Sbjct: 255 GPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 314

Query: 596 GQDGT---RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM---PGLMGSNGSPGQP 649
           G +G    RGEPG PG PG  G  G  G  G PG +G  GAPG+   PG  G  G PG  
Sbjct: 315 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 374

Query: 650 GTPGS---KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEK 706
           G  G    KG  GEPGI G  G  G KGEPG  G  G PG  G  G +G +G+ G  G  
Sbjct: 375 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 434

Query: 707 GIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKG---------------EPGVRGAIGSK 751
           G  G++G  G +G PGQ G+ G  GA GERG  G               EPG+ GA G  
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494

Query: 752 GESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQF--IRQVCTDVIRAQLPVLL 809
           G  G  G  G  GP G PG+ G  GPPG  G  G+     F   +    +  +A    L 
Sbjct: 495 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP 554

Query: 810 QSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLK 869
            +  +R       + G  G  GPPGP GP G RG  G PG  G  GL G PG PG  G  
Sbjct: 555 GAPGLRGLP---GKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 611

Query: 870 GLPGRNGEKGSQGF-------GYPGEQGPPGPPGPEGPPGI----SKEGPPGDPGLPGKD 918
           G  G  GE G+ G        G+PGE+G PG  G +GP G+      +GP G  G  G  
Sbjct: 612 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 671

Query: 919 GDHGKPGIQGQPGPPG 934
           G  G PG+QG PG  G
Sbjct: 672 GAQGPPGLQGMPGERG 687



 Score =  380 bits (976), Expect = e-105
 Identities = 247/606 (40%), Positives = 295/606 (48%), Gaps = 120/606 (19%)

Query: 424 PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK------ 477
           PG +GE    P   G        PPG  G +G  G PGLPG  G+ G PG DG       
Sbjct: 182 PGDDGEA-GKPGKAGERG-----PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235

Query: 478 PGYQGIAGTPGVPGSPGIQGARGLPGYKGEPG---------RDGDKGDRGLPGFPGLHGM 528
           PG +G +G+PG  GSPG  G RGLPG +G  G          DG  G  G PG  G  G 
Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295

Query: 529 PGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGE 588
           PG  G  GAKG+ G  G  G +GA+G +G  G PG PGPAG  G  G DG+ G+ G  G 
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355

Query: 589 AGSPGAPGQDGTR------------------GEPGIPGFPGNRGLMGQ------KGEIGP 624
            G  GAPG  G R                  GEPGI GF G +G  G+      +G  GP
Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 415

Query: 625 PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA------SGLKGEPGA 678
            G++GK+GA G PG +G  G PG+ G PG++G  G+ G+ G  GA      SGL G  GA
Sbjct: 416 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 475

Query: 679 TGSPGEPGYMGLP---GIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGH------ 729
            G PG PG  GLP   G+ G+ GD G QG+ G  G  GE+GR G PG QG +G       
Sbjct: 476 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 535

Query: 730 ---HGAKGERGEKGE------PGVRGAIGSKGESGVDGLMGPAGPKGQPGD--------- 771
               GA GE G+ GE      PG+RG  G  GE+G  G  GPAGP G+ G+         
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595

Query: 772 ---PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPG 828
              PGP GPPG  GKPG +               A  P L+             + G PG
Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPG----------EAGAPGLVGP---------RGERGFPG 636

Query: 829 IPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYP-- 886
             G PG  G +GPRGLPG PG DG  G  G  G PG +G  GL G  GE+G+ G   P  
Sbjct: 637 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696

Query: 887 -----GEQGPPGPP---------GPEGPPGIS----KEGPPGDPGLPGKDGDHGKPGIQG 928
                GE+GP G P         GP GPPG +    ++G  G PG  G  G  G PG +G
Sbjct: 697 DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 756

Query: 929 QPGPPG 934
           + GPPG
Sbjct: 757 ETGPPG 762



 Score =  372 bits (956), Expect = e-103
 Identities = 216/522 (41%), Positives = 261/522 (50%), Gaps = 75/522 (14%)

Query: 447 PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
           P G PG +GP G  G  G  G PG+PG+ G PG +G+ G PG  G  G  G  G PG  G
Sbjct: 457 PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 516

Query: 507 EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
            PG  G +G RG PG  G  G  G+ GE G  G+KG PG  G +G  G+ G  G  G PG
Sbjct: 517 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576

Query: 567 PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPG 626
           PAG  G  G+ G  G  GF+G  G PG PG+ G  G+ G+PG  G  GL+G +GE G PG
Sbjct: 577 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 636

Query: 627 QQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPG 686
           ++G  GA G+ G  G  G+PG  G  G+ G  G PG QG PG  G+ GE GA G      
Sbjct: 637 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG------ 690

Query: 687 YMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRG 746
                 I G KGD+G+ GEKG +G  G++G +G+ G  G  G  GA GE+GE G PG  G
Sbjct: 691 ------IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 744

Query: 747 AIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLP 806
           + G++G  G  G  GP GP G  G PG  G PG  G+ G                     
Sbjct: 745 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEA------------------- 785

Query: 807 VLLQSGRIRNCDHCLSQHGSPGIPGPPGPI---GPEGP---------RGLPGLPGRDGVP 854
                           Q G  G PGP GP    GP+GP         RG  G PG  G P
Sbjct: 786 ---------------GQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830

Query: 855 GLVGVPGRPGVRGLKGLP------GRNGEKGSQG-------FGYPGEQGPPGPPGPEGPP 901
           G  G  G PG  G  G P      G++G KG++G        G PG QGP GPPG +G P
Sbjct: 831 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 890

Query: 902 G----ISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
           G       EGPPG  GL G+ G  G PG +G+ G PG+  PS
Sbjct: 891 GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932



 Score =  370 bits (951), Expect = e-102
 Identities = 220/527 (41%), Positives = 255/527 (48%), Gaps = 82/527 (15%)

Query: 449 GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGY---------------------------- 480
           G PG +G  G+PG PGNPG PG PG  G PG                             
Sbjct: 75  GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 134

Query: 481 --QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAK 538
              G  G PG  G+PG QG +G PG  GEPG  G  G RG PG PG  G  G  G+ G  
Sbjct: 135 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 194

Query: 539 GDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQD 598
           G++G PG    +GA+G  G  G PG+ G  G PG  G  G  G+PG KGE+GSPG   ++
Sbjct: 195 GERGPPG---PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG---EN 248

Query: 599 GTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSK 658
           G+ G  G  G PG RG  G  G  G  G  G+ G  G PG +G  G PG PG PG+KG  
Sbjct: 249 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 308

Query: 659 GEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQ 718
           G  G +G  GA G +GEPG  GSPG  G  G PG  G  G KG+ G  GI G  G  G +
Sbjct: 309 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 368

Query: 719 GIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGP---------KGQP 769
           G PG QG  G  G KG+ GE G  G +G  G KGE G  G  G  GP         +G+P
Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 428

Query: 770 GDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI 829
           G  GP GPPG  G PG                                       G  G+
Sbjct: 429 GGVGPIGPPGERGAPGNR----------------------------------GFPGQDGL 454

Query: 830 PGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGE 888
            GP G  G  GP GL G  G +G PG  G PG PG RGL G PG  G +G  G  G PGE
Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514

Query: 889 QGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
            G PGPPGP+G  G  + G  G PG  G +G+ GK G +G PG PG+
Sbjct: 515 DGRPGPPGPQGARG--QPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 559



 Score =  321 bits (822), Expect = 2e-87
 Identities = 197/479 (41%), Positives = 236/479 (49%), Gaps = 69/479 (14%)

Query: 445  ICPPGKPGLQGPKGDPGLPGNPGY------PGQPGQDGKPGYQGIAGTPGVPGSPGIQGA 498
            I PPG  G  G KG+ G PG  G       PG+ G+ G PG  G AG PG  G PG +G 
Sbjct: 722  IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 781

Query: 499  RGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGN 558
            +G  G KG+ G  G +G  G PG  G  G+ G KG  GA+G  G+ GF G  G  G  G+
Sbjct: 782  QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 841

Query: 559  AGFPGLPGPAGEPGRHGKDGLMGS---------PGFKGEAGSPGAPGQDGTRGEPGIPGF 609
             G PG PGP G  G+ G  G  G          PG +G AG PG  G+ G  G  G  G 
Sbjct: 842  NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP 901

Query: 610  PGNRGLMGQKGEIGPPGQQGKKGAPGMPG------------LMGSNGSPGQPGTPGSKGS 657
            PG +GL GQ+G +G PGQ+G++G PG+PG              G  G PG  G PG  G 
Sbjct: 902  PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 961

Query: 658  KGEPGIQGMPGA---------SGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
             GEPG +G PGA         +G+KG+ G TG+ G PG  G PG  G  G  G QG++G 
Sbjct: 962  AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021

Query: 709  QGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQ 768
             G +G  G  G  G +GIQG  G +G++GE GEPG RG  G +G +G+ GL GP GP G 
Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1081

Query: 769  PGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPG 828
             G  GP GP G  G PG                    PV   SG+          +G PG
Sbjct: 1082 QGASGPAGPSGPRGPPG--------------------PVG-PSGKD-------GANGIPG 1113

Query: 829  IPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGV--RGLKGLPGRNGEKGSQGFGY 885
              GPPGP G  G  G  G PG  G PG  G PG PG+      GL  R  EKG     Y
Sbjct: 1114 PIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG-PGIDMSAFAGLGPR--EKGPDPLQY 1169



 Score =  308 bits (789), Expect = 2e-83
 Identities = 197/496 (39%), Positives = 229/496 (46%), Gaps = 86/496 (17%)

Query: 502 PGYKGEPGRDGD----KGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKG 557
           PG KG+ G  GD     G +G PG  G  G  G +G+ G KG+KG+PG  G+ G  G  G
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG 90

Query: 558 NAGFPGLPGPAGEPGRHGK---------------------DGLMGSPGFKGEAGSPGAPG 596
           N G PG PGP G PG  G                       G MG  G +G  G  GAPG
Sbjct: 91  NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150

Query: 597 QDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQG---------KKGAPGMPGLMGSNGSPG 647
             G +G PG PG PG  G MG +G  GPPG+ G         K G  G PG  G+ G PG
Sbjct: 151 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPG 210

Query: 648 QPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKG 707
            PG PG KG +G PG+    GA G  G PG  G  G PG  G PG  G +G  G +G  G
Sbjct: 211 TPGLPGVKGHRGYPGLD---GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG 267

Query: 708 IQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKG 767
             G  G  G  G PG  G  G  G  G  G  G PG +G  G  G  G +G  GP G  G
Sbjct: 268 PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG 327

Query: 768 QPGDPGP---QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQH 824
            PG PGP    G PG DG PG + S             A  P +                
Sbjct: 328 TPGSPGPAGASGNPGTDGIPGAKGS-------------AGAPGIA--------------- 359

Query: 825 GSPGIPGPPGPIGPE------GPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEK 878
           G+PG PGP GP GP+      GP+G  G PG  G  G  G  G PG  G +G PG  GE+
Sbjct: 360 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 419

Query: 879 GSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
           G +     G +G PG  GP GPPG  + G PG+ G PG+DG  G  G  G+ GP G+  P
Sbjct: 420 GKR-----GARGEPGGVGPIGPPG--ERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 472

Query: 939 SLCFSVIARRDPFRKG 954
                  A  DP R G
Sbjct: 473 K-----GANGDPGRPG 483



 Score =  207 bits (526), Expect = 5e-53
 Identities = 137/362 (37%), Positives = 159/362 (43%), Gaps = 64/362 (17%)

Query: 618 QKGEIGPPGQQGKKGAPG-MPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEP 676
           Q  ++  PG +G+KG PG +  ++G  G PG  G  G +G +G+ G +G  GA G +G  
Sbjct: 24  QGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 83

Query: 677 GATGSPGEPGYMGLPGIQGKKGDKGN---------------------QGEKGIQGQKGEN 715
           G  G+PG PG  G PG  G  G  GN                     QG  G  G +G  
Sbjct: 84  GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 143

Query: 716 GRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQ 775
           G  G PG QG QG+ G  GE G  G  G RG  G  G+ G DG  G  G  G+ G PGPQ
Sbjct: 144 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 776 GPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI------ 829
           G  G  G PG                   LP +         D    + G+PG+      
Sbjct: 204 GARGFPGTPG-------------------LPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244

Query: 830 PGPPGPIGPEGPRGLPGLPGR------------DGVPGLVGVPGRPGVRGLKGLPGRNGE 877
           PG  G  GP GPRGLPG  GR            DG PG  G PG  G  G  G PG  G 
Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304

Query: 878 KGSQG----FGYPGEQGPPGPPGPEGPPG-ISKEGPPGDPGLPGKDGDHGKPGIQGQPGP 932
           KG  G     G  G QGP G PG  G PG     G PG  G+PG  G  G PGI G PG 
Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364

Query: 933 PG 934
           PG
Sbjct: 365 PG 366


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  386 bits (991), Expect = e-107
 Identities = 218/503 (43%), Positives = 260/503 (51%), Gaps = 30/503 (5%)

Query: 447 PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
           PPG  GL G  G  GLPG+PG  G+ G +G  G +G+ G  G PG  G  G  G  G +G
Sbjct: 480 PPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARG 539

Query: 507 EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
            PG  G KGDRG  G PGL G  G +G+ G  G  G PG  G++GA+G  G  G  G PG
Sbjct: 540 LPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPG 599

Query: 567 PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPG 626
           P G  G  G  G  G PG  G  G+PGA G  G  GEPG PG  GN G  G  G  G  G
Sbjct: 600 PRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIG 659

Query: 627 QQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPG 686
             G+KG PG PG+ G  GS G  G PG +G  GE G QG PG++G  G PG  G  G  G
Sbjct: 660 TPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSG 719

Query: 687 YMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRG 746
             GL G +G+KG+ G  G KG  G KG+ G+ G PG +G  G  G KG+ G+ GE G  G
Sbjct: 720 NRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPG 779

Query: 747 AIGSKGESGVDGLMG---PAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRA 803
           + G KG+ GV GL G     GPKG  G PGP GP G  GK G+        +        
Sbjct: 780 SAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGE-------- 831

Query: 804 QLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRP 863
                      R       + G PG  G PGP G  G  G PG+PG  G+PGL G PG P
Sbjct: 832 -----------RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFP 880

Query: 864 GVRGLKGLPGRNGEKGSQG----FGYPGEQGPPGPPGPEGPPGISKE----GPPGDPGLP 915
           G +G  G  G++G  G  G     G+ G+ GPPGP G  GP G + E    G  G PG P
Sbjct: 881 GPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPP 940

Query: 916 GKDGDHGKPGIQGQPGPPGICDP 938
           G  G+ G PG++G+ G  G   P
Sbjct: 941 GPPGEQGLPGLEGREGAKGELGP 963



 Score =  378 bits (971), Expect = e-104
 Identities = 237/550 (43%), Positives = 276/550 (50%), Gaps = 66/550 (12%)

Query: 447  PPGKPGLQGPKGDPGLPGN---PGYPGQPGQDGK------PGYQGIAGTPGV---PGSPG 494
            P G+PG+ G  G PG  GN   PG PG PGQ G       PG QG+ GTPG    PG+PG
Sbjct: 612  PTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPG 671

Query: 495  IQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKG 554
            I G  G  G  G PG +G  G++G  G PG  G PG  G  G KG  G+ G  G+KG KG
Sbjct: 672  IPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKG 731

Query: 555  E------------KGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG 602
            E            KG+ G PG PGP GE G  G  G  G  G +G  GS G  G+ G  G
Sbjct: 732  EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791

Query: 603  EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSP------GQPGTPGSKG 656
             PG PG PG +G +G  G +GP G++GK G  G PGL G  G P      GQPG  G  G
Sbjct: 792  LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851

Query: 657  SKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGK---KGDKGNQGEKGIQGQKG 713
             KG+ G  G PG  G KG PG  G PG PG  G PG QGK    G  G +GE G QGQ G
Sbjct: 852  PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911

Query: 714  ENGRQGIPGQQGIQGHHGAKGER---------GEKGEPGVRGAIGSKGESGVDGLMGPAG 764
              G  G+ G QG  G  G  GER         GE+G PG+ G  G+KGE G  G +G  G
Sbjct: 912  PPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEG 971

Query: 765  PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQH 824
            P G  G PGP+G PG  G  G +  +     V  +    +   L  +G I        Q 
Sbjct: 972  PAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGI----GLPGQS 1027

Query: 825  GSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGV---------RGLKGLPGRN 875
            GS G  GP G  G  G RG PG  G+DG+PG +G  G PG          +G  G PG  
Sbjct: 1028 GSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHK 1087

Query: 876  GEKGSQGF----GYPGEQGPPGPPGPEGPPGI-SKEGPP------GDPGLPGKDGDHGKP 924
            G KG +G     G PG +GP G PGP G  G   + GPP      GD G+ G  G  G P
Sbjct: 1088 GSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPP 1147

Query: 925  GIQGQPGPPG 934
            G+QG PGPPG
Sbjct: 1148 GLQGLPGPPG 1157



 Score =  374 bits (959), Expect = e-103
 Identities = 234/538 (43%), Positives = 272/538 (50%), Gaps = 61/538 (11%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PG  GE  +G       P P     G+PG +G  G  G PG  G PG  G DG PG +G 
Sbjct: 574  PGPPGE--DGERGAEGPPGPT-GQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGN 630

Query: 484  AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
             G PG PG PG QG  G  G  G  G  G  G++G PG PG+ G+PGS G +G  G +G 
Sbjct: 631  VGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGP 690

Query: 544  PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
             G   +KGA+G  G+AG PG PGP G  G  G  GL G  G KGE G PG  G  G +G+
Sbjct: 691  TG---EKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGD 747

Query: 604  PGIPGFPGNR---------GLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGT--- 651
             G PG PG R         G  GQ GE GPPG  G+KG  G+PGL G  G PG  G+   
Sbjct: 748  QGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF 807

Query: 652  PGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQ 711
            PG  G  GE G  G  G  GL+GE G  GS GE G  G  G  G KGD G  G  GI G+
Sbjct: 808  PGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGE 867

Query: 712  KGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGD 771
            KG  G QG PG  G +G  G +G+ G  G PG RG +G +G++G  G  G  GP+G+ G+
Sbjct: 868  KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGE 927

Query: 772  PGP---QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPG 828
             GP   +GPPG  G PG +                 LP L   GR           G+ G
Sbjct: 928  VGPLGERGPPGPPGPPGEQ----------------GLPGL--EGR----------EGAKG 959

Query: 829  IPGPPGPIGPEGPRGLPGLPGRDGVP------GLVGVPGRPGVRGLKGLPGRNGEKG-SQ 881
              GPPGP+G EGP GL G PG  G P      GL G  G PG  G  G PG  G  G + 
Sbjct: 960  ELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAG 1019

Query: 882  GFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
            G G PG+ G  GP GP G     K+G  G+ G PG  G  G PG  G  GPPG   PS
Sbjct: 1020 GIGLPGQSGSEGPVGPAG-----KKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPS 1072



 Score =  374 bits (959), Expect = e-103
 Identities = 242/597 (40%), Positives = 291/597 (48%), Gaps = 82/597 (13%)

Query: 412  PEQNNRETACEIPGFNGECLNGPSDVGSTPAPCIC-------PPGKPGLQGPKGDPGLPG 464
            P Q     +  +PG  G  +  P + G    P I        P G PG +GP G+ G  G
Sbjct: 640  PGQQGNHGSQGLPGPQG-LIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQG 698

Query: 465  NPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPG 524
             PG  G PG  G  G +G +G  G+ G  G +G  G PG+KG+ G  GD+G  G PG  G
Sbjct: 699  PPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRG 758

Query: 525  LHGMPGSKGEMGAKGDKGSPGFYGKKGA------------KGEKGNAGFPGLPGPAGEPG 572
              G  G KG+ G  G++G PG  G+KG              G KG+ GFPG  GP GE G
Sbjct: 759  EDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG 818

Query: 573  RHGK------DGLMGSPGFKGEAGSPGAPGQDGTR---GEPGIPGFPGNRGLMGQK---- 619
            + GK      +G  G PG +GE G PGA GQ G +   G+ G PG PG +GL G +    
Sbjct: 819  KSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPG 878

Query: 620  --GEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
              G  GPPG QGK G PG PG  G  G  GQ G PG  G  G    QG  G  G  GE G
Sbjct: 879  FPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGP---QGKTGEVGPLGERG 935

Query: 678  ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG 737
              G PG PG  GLPG++G++G KG  G  G  G++G  G +G PG +G  G  G  G +G
Sbjct: 936  PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKG 995

Query: 738  EKGEPGVRGAIGSKGE---------------SGVDGLMGPAGPKGQPGDPGPQGPPGLDG 782
            +KG PG  GA GS GE               SG +G +GPAG KG  G+ GP GP G DG
Sbjct: 996  DKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDG 1055

Query: 783  KPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQ--------HGSPGI----- 829
             PG       +  +               G +    H  S+         G PGI     
Sbjct: 1056 IPGP------LGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAG 1109

Query: 830  -PGPPGPIGPEGPRGLPGL---PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG--- 882
             PGPPG  G +G RG PGL    G DGV G VGV G PG++GL G PG  GE G  G   
Sbjct: 1110 HPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMG 1169

Query: 883  -FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
              G PG +GP GP G EG PG+   G  G PG  G+ G+ G  G  G PG PGI  P
Sbjct: 1170 PHGAPGPRGPQGPTGSEGTPGL--PGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGP 1224



 Score =  373 bits (958), Expect = e-103
 Identities = 224/533 (42%), Positives = 267/533 (50%), Gaps = 57/533 (10%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPG---------------QDGKPGYQGIAGTPGVPGSP 493
            G PG  G KG  G+PG PGYPG+PG               + GK G  G  G  G  G P
Sbjct: 776  GPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPP 835

Query: 494  GIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGA- 552
            G +G RG PG  G+PG  GD G  G PG PG  G+PG +G  G  G KG PG  GK G  
Sbjct: 836  GSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895

Query: 553  --KGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
               G++G  GF G  GP G  G  G  G  G  G  GE G PG P      G PG  G P
Sbjct: 896  GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPP------GPPGEQGLP 949

Query: 611  GNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEP---GIQGMP 667
            G  G  G KGE+GPPG  GK+G  G+ G  G  G PG PG  G KG KG P   G  G P
Sbjct: 950  GLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSP 1009

Query: 668  GASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQ 727
            G  G  G  G  G PG+ G  G  G  GKKG +G +G  G  G+ G  G  G  G  G  
Sbjct: 1010 GERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAA 1069

Query: 728  GHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGP------QGPPGLD 781
            G  G +G++G+ G PG +G+ G KG++G  G  G  GP G PG PG       +GPPGL 
Sbjct: 1070 GPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLF 1129

Query: 782  GKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP 841
            G+ G +    F+  +    ++       + G + +    +   G  G PGP GP GP G 
Sbjct: 1130 GQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD----VGSMGPHGAPGPRGPQGPTGS 1185

Query: 842  RGLPGLPGRDGVPGLVGV---------PGRPGVRGLKGLPGRNGEKGSQG----FGYPGE 888
             G PGLPG  G PG VG          PG PG  G+ G  G  GEKG  G     G PG+
Sbjct: 1186 EGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGK 1245

Query: 889  QGPPGPPGPE---GPPGISKE-GPPGDPGLPGKD---GDHGKPGIQGQPGPPG 934
            +GPPG  G +   GP G+  + GPPGDPG+ G D   G+ G PG  G PGPPG
Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPG 1298



 Score =  372 bits (955), Expect = e-103
 Identities = 232/552 (42%), Positives = 278/552 (50%), Gaps = 52/552 (9%)

Query: 424  PGFNGEC-LNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            PGF G+  L G  D G   AP   P G+ G +GPKG  G  G  G PG  G+ GK G  G
Sbjct: 736  PGFKGDVGLKG--DQGKPGAPG--PRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791

Query: 483  IAGTPGVPGS------PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536
            + G PG PG       PG  G  G  G  G+ G+ G +G+RG PG  G  G PG+ G+ G
Sbjct: 792  LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851

Query: 537  AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPG------FKGEAG 590
             KGD G  G  G  G KG  G  G PG PGP G PG  GKDG  G PG      F+G+ G
Sbjct: 852  PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911

Query: 591  SPGAPG------------QDGTRGEPGIPGFPGNRGLMG------QKGEIGPPGQQGKKG 632
             PG  G              G RG PG PG PG +GL G       KGE+GPPG  GK+G
Sbjct: 912  PPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEG 971

Query: 633  APGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPG 692
              G+ G  G  G PG PG  G KG KG PG  G  G+ G +G  G  G  G PG  G  G
Sbjct: 972  PAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEG 1031

Query: 693  IQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGE---PGVRGAIG 749
              G  G KG++GE+G  G  G++G  G  G  G  G  G  GE G+KG+   PG +G+ G
Sbjct: 1032 PVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKG 1091

Query: 750  SKGESGVDGLMGPAGPKGQPGDPGP------QGPPGLDGKPGREFSEQFIRQVCTDVIRA 803
             KG++G  G  G  GP G PG PG       +GPPGL G+ G +    F+  +    ++ 
Sbjct: 1092 DKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQG 1151

Query: 804  QLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRP 863
                  + G + +    +   G  G PGP GP GP G  G PGLPG  G PG VG  G  
Sbjct: 1152 LPGPPGEKGEVGD----VGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGER 1207

Query: 864  GVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGK 923
            G  G  G PG  G  G +G    GE+G  GP G  GPPG  K+GPPG+ G  G  G  G 
Sbjct: 1208 GDAGDPGPPGAPGIPGPKGD--IGEKGDSGPSGAAGPPG--KKGPPGEDGAKGSVGPTGL 1263

Query: 924  PGIQGQPGPPGI 935
            PG  G PG PG+
Sbjct: 1264 PGDLGPPGDPGV 1275



 Score =  371 bits (952), Expect = e-102
 Identities = 233/595 (39%), Positives = 282/595 (47%), Gaps = 129/595 (21%)

Query: 447 PPGKPGLQG------PKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPG------------ 488
           PPG PG QG      P G PG PG+PG PG  G  G PG  GI G PG            
Sbjct: 393 PPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGG 452

Query: 489 ---------------------------------VPGSPGIQGARGLPGYKGEPGRDGDKG 515
                                            + G PG  G  G PG KGE G +G +G
Sbjct: 453 SFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQG 512

Query: 516 DRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP-------- 567
            RGL G    HG PG  G+MG  G  G+ G  G  G KG++G  G PGLPG         
Sbjct: 513 PRGLQG---PHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFG 569

Query: 568 -AGEPGRHGKDGLMGS---PGFKGEAGSPGAPGQDGTRGEP---------GIPGFPGNRG 614
             G+PG  G+DG  G+   PG  G+AG PG  G  G RG P         GI G PG +G
Sbjct: 570 HVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKG 629

Query: 615 LMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQ---------PGTPGSKGSKGEPGIQG 665
            +G  GE GPPGQQG  G+ G+PG  G  G+PG+         PG PGS G  G PG +G
Sbjct: 630 NVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEG 689

Query: 666 MPGASGLKGEPGATGSPGEPGYMGLP------GIQGKKGDKGNQGEKGIQGQ---KGENG 716
             G  G +G PG+ G PG PG  G+       G+QG+KG+KG  G  G +G    KG+ G
Sbjct: 690 PTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQG 749

Query: 717 RQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGL---MGPAGPKGQPGDPG 773
           + G PG +G  G  G KG+ G+ GE G  G+ G KG+ GV GL    G  GPKG  G PG
Sbjct: 750 KPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPG 809

Query: 774 PQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPP 833
           P GP G  GK G+        +                   R       + G PG  G P
Sbjct: 810 PLGPIGEKGKSGKTGQPGLEGE-------------------RGPPGSRGERGQPGATGQP 850

Query: 834 GPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG----FGYPGEQ 889
           GP G  G  G PG+PG  G+PGL G PG PG +G  G  G++G  G  G     G+ G+ 
Sbjct: 851 GPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQT 910

Query: 890 GPPGPPGPEGPPG-------ISKEGPPGDPGLPGKD---GDHGKPGIQGQPGPPG 934
           GPPGP G  GP G       + + GPPG PG PG+    G  G+ G +G+ GPPG
Sbjct: 911 GPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPG 965



 Score =  367 bits (942), Expect = e-101
 Identities = 240/584 (41%), Positives = 286/584 (48%), Gaps = 77/584 (13%)

Query: 425  GFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQ---PGQDGKPGYQ 481
            GF G+   GP      PA  + P GK G  GP G+ G PG PG PG+   PG +G+ G +
Sbjct: 905  GFQGQ--TGPPG----PAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK 958

Query: 482  GIAGTPGVPGSPGIQGARGLPGYKG---EPGRDGDKGDRGLPGFPGLHGMPGSKGEMG-- 536
            G  G PG  G  G  G RG PG KG   +PG  G KGD+G PG  G +G PG +G +G  
Sbjct: 959  GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA 1018

Query: 537  ----------------------AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRH 574
                                  ++G++G PG  GK G  G  G  G PG  GP+GE G  
Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDK 1078

Query: 575  GKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRG---------LMGQKGE---- 621
            G  G  G  G KG+ G  G PGQ G RG  G PG PG  G         L GQKG+    
Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVR 1138

Query: 622  -----IGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEP 676
                 IGPPG QG  G PG  G +G  GS G  G PG +G +G  G +G PG  G  G+P
Sbjct: 1139 GFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQP 1198

Query: 677  GATGSPGE------PGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGH- 729
            GA G  GE      PG  G PGI G KGD G +G+ G  G  G  G++G PG+ G +G  
Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258

Query: 730  --HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDG----- 782
               G  G+ G  G+PGV G  GS GE G  G +G  GP G  G+PG  GPPG  G     
Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHM 1318

Query: 783  -KPGREFSEQFIRQVCTDVIRAQL-PVLLQS--GRI--RNCDHCLSQHGSPGIPGPPGPI 836
             + GRE  +    +   D    +  P+  +   GR+            G PG+ G PG +
Sbjct: 1319 GREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQM 1378

Query: 837  GPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPG 896
            GP GP G  GLPG  G  G  G  G  G+ GL G PG  GEKG QG   PG QGPPGP G
Sbjct: 1379 GPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGL--PGVQGPPGPKG 1436

Query: 897  PEGPPG-ISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
              GPPG I   G PG PG+ G  G  G  G  G  GP G   P+
Sbjct: 1437 DPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPA 1480



 Score =  366 bits (940), Expect = e-101
 Identities = 240/605 (39%), Positives = 284/605 (46%), Gaps = 106/605 (17%)

Query: 424  PGFNGECLNGPS-DVGSTPAPCIC-PPGKPGLQGPKGDPGLPGNPGY------PGQPGQD 475
            PG  G+   GP  DVG   AP I    G PGLQGP G PG  G PG+      PG PGQ 
Sbjct: 844  PGATGQ--PGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQR 901

Query: 476  GKPGYQGIAGTPGV---------------------PGSPGIQGARGLPGYKGE------- 507
            G+ G+QG  G PG                      PG PG  G +GLPG +G        
Sbjct: 902  GELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGEL 961

Query: 508  --PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLP 565
              PG  G +G  GL GFPG  G PG  G  G KGDKG PG  G  G+ GE+G  G  G  
Sbjct: 962  GPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGI 1021

Query: 566  GPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGI---PGFPGNRGLMGQKGEI 622
            G  G+ G  G  G  G  G +GE G PG  G+DG  G  G    PG  G  G  G KG++
Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDV 1081

Query: 623  GPPGQQGKKG------APGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEP 676
            G PG +G KG       PG PG+ G  G PG PG  G++G +G PG+ G  G  G++G  
Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFV 1141

Query: 677  GATGSPGEPGYMGLPGIQGKKGDKGNQGE------KGIQGQKGENGRQGIPGQQGIQGHH 730
            G  G PG  G  G PG +G+ GD G+ G       +G QG  G  G  G+PG  G  G  
Sbjct: 1142 GVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAV 1201

Query: 731  GAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSE 790
            G KGERG+ G+PG  GA G  G  G  G  G +GP G  G PG +GPPG DG  G     
Sbjct: 1202 GEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKG----- 1256

Query: 791  QFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGR 850
                 V    +   L      G +   D    + G PG  G PGP G  G  G PG PG+
Sbjct: 1257 ----SVGPTGLPGDLGPPGDPG-VSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGK 1311

Query: 851  ------------------DGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG---------- 882
                               G PG  G PGR G  G +G PGR G +G +G          
Sbjct: 1312 RGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGL 1371

Query: 883  FGYPGEQGPPGPPGPEGPPGISKE-GPPGD------------PGLPGKDGDHGKPGIQGQ 929
             G PG+ GPPGP GP G PG+  + GP G+            PG  G+ GD G PG+QG 
Sbjct: 1372 LGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGP 1431

Query: 930  PGPPG 934
            PGP G
Sbjct: 1432 PGPKG 1436



 Score =  337 bits (864), Expect = 3e-92
 Identities = 203/494 (41%), Positives = 242/494 (48%), Gaps = 60/494 (12%)

Query: 433  GPSDVGSTPAPCICPPGKPGLQGP------KGDPGLPGNPGYPGQPGQDGKPGYQGI--- 483
            GP+     P P + P G PG  GP      KGD G PG+ G  G  G  G PG  GI   
Sbjct: 1049 GPTGKDGIPGP-LGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGP 1107

Query: 484  AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
            AG PG PG+ G QG RG PG  G+ G DG +G  G+ G PGL G+PG  GE G  GD GS
Sbjct: 1108 AGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGS 1167

Query: 544  PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
             G +G  G +G +G  G  G PG    PG  G+ G +G  G +G+AG PG PG       
Sbjct: 1168 MGPHGAPGPRGPQGPTGSEGTPGL---PGGVGQPGAVGEKGERGDAGDPGPPGA------ 1218

Query: 604  PGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGI 663
               PG PG +G +G+KG+ GP G  G  G  G PG  G+ GS G  G PG  G  G+PG+
Sbjct: 1219 ---PGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGV 1275

Query: 664  QGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ 723
             G+ G+ G KG+PG  G PG PG  G PG  G  G +G  G  G +G++GE G +G PG 
Sbjct: 1276 SGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGP 1335

Query: 724  QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGK 783
             G  G  G  G RG  G  G  G  G  G  G  GL+G  G  G PG  GP G PGL G 
Sbjct: 1336 DGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGD 1395

Query: 784  PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRG 843
             G +  +  I                               G  G+ GPPG  G +G +G
Sbjct: 1396 TGPKGEKGHI-------------------------------GLIGLIGPPGEAGEKGDQG 1424

Query: 844  LPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGI 903
            LPG+    G PG  G PG PG  G  G PG  G  G    G  G +G PG  GP G  G 
Sbjct: 1425 LPGV---QGPPGPKGDPGPPGPIGSLGHPGPPGVAGP--LGQKGSKGSPGSMGPRGDTG- 1478

Query: 904  SKEGPPGDPGLPGK 917
               GPPG PG P +
Sbjct: 1479 -PAGPPGPPGAPAE 1491



 Score =  293 bits (750), Expect = 5e-79
 Identities = 188/461 (40%), Positives = 224/461 (48%), Gaps = 62/461 (13%)

Query: 447  PPGKPGLQGPKGDPGLPGN---------PGYPGQPGQDGKPGYQGIAGTPGVPGSPG--- 494
            PPG+PG++GP G PG PG          PG  GQ G DG  G+ G+ G PG+ G PG   
Sbjct: 1098 PPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPG 1157

Query: 495  ---------------------------IQGARGLPGYKGEPGRDGDKGDRGL---PGFPG 524
                                        +G  GLPG  G+PG  G+KG+RG    PG PG
Sbjct: 1158 EKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPG 1217

Query: 525  LHGMPGSKGEMGAKGDKGSPGFYG---KKGAKGE---KGNAGFPGLPGPAGEPGRHGKDG 578
              G+PG KG++G KGD G  G  G   KKG  GE   KG+ G  GLPG  G PG  G  G
Sbjct: 1218 APGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSG 1277

Query: 579  LMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPG 638
            + GSPG KG+ G  G PG  G  GEPG PG PG RG  G  G  G  G++G KG PG  G
Sbjct: 1278 IDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDG 1337

Query: 639  LMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKG 698
              G  G  G  G PG  G +G  GI G  G  GL G PG  G PG  G  GLPG++G  G
Sbjct: 1338 PPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTG 1397

Query: 699  DKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDG 758
             KG +G  G+ G  G  G  G  G QG+ G  G  G +G+ G PG  G++G  G  GV G
Sbjct: 1398 PKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAG 1457

Query: 759  LMGPAGPKGQP------GDPGPQGPPGLDGKP----GREFSEQFIRQVCTDVIRAQLPVL 808
             +G  G KG P      GD GP GPPG  G P    G     +F+  V   V+   L  +
Sbjct: 1458 PLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFV-PVPLPVVEGGLEEV 1516

Query: 809  LQSGRIRNCDHCLSQ-HGSPGIPGPPGPIGPEGPRGLPGLP 848
            L S  + +    L Q    PG    PG +  E  R  P LP
Sbjct: 1517 LAS--LTSLSLELEQLRRPPGTAERPGLVCHELHRNHPHLP 1555



 Score =  238 bits (607), Expect = 2e-62
 Identities = 233/793 (29%), Positives = 313/793 (39%), Gaps = 199/793 (25%)

Query: 248 QLSPKKIKGYEVTSKVDLSELTSNVFPEG-LPPSYVFVSTQRFKVKKIWDLWRILTIDGR 306
           Q +P+  + + +     L   T  +FPEG  P ++  + T R +      L  I    G 
Sbjct: 56  QRTPEGDRAFRIGQASTLGIPTWELFPEGHFPENFSLLITLRGQPANQSVLLSIYDERGA 115

Query: 307 PQIAVTLNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYID 366
            Q+ + L     +L      +           PQ   L D  WH++ + +  + VTL  D
Sbjct: 116 RQLGLALGPALGLLGDPFRPL-----------PQQVNLTDGRWHRVAVSIDGEMVTLVAD 164

Query: 367 DQQIENKPLHPVLG-----ILINGQTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETAC 421
               E +P  PVLG     I I G T +G     E+T + D+Q+L I  DP+   +  AC
Sbjct: 165 ---CEAQP--PVLGHGPRFISIAGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQ--AC 217

Query: 422 EIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQ 481
           E   +  +C N        PA  + P G+P    P+      G     G+ G+  K   +
Sbjct: 218 E--RYLPDCDN------LAPAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKE 269

Query: 482 GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLH-----------GMPG 530
               +P  P S   Q +  +P           K +   P  P              G+  
Sbjct: 270 IWTSSPP-PDSAENQTSTDIP-----------KTETPAPNLPPTPTPLVVTSTVTTGLNA 317

Query: 531 SKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAG 590
           +  E     D G+           E G      L   A      G D  MG      E  
Sbjct: 318 TILERSLDPDSGT-----------ELGT-----LETKAAREDEEGDDSTMGPDFRAAEYP 361

Query: 591 S-------PGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643
           S       PGA G+ G +GEP +          GQ+ E GPPG      APG  G++G +
Sbjct: 362 SRTQFQIFPGA-GEKGAKGEPAVIE-------KGQQFE-GPPG------APGPQGVVGPS 406

Query: 644 GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA------------------------- 678
           G PG PG PG  G  G  G+ G+PG  G++G PG                          
Sbjct: 407 GPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQA 466

Query: 679 --------------------TGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQ------GQK 712
                               TG PG  G  G PG++G++G +G QG +G+Q      G+ 
Sbjct: 467 QAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRV 526

Query: 713 GENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSK------------GESGVDGLM 760
           G+ GR G  G +G+ G  G KG+RG  G PG+ G  G +            GE G  G  
Sbjct: 527 GKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAE 586

Query: 761 GPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGR--IRNCD 818
           GP GP GQ G+PGP+G  G  G PG                         +GR  +   D
Sbjct: 587 GPPGPTGQAGEPGPRGLLGPRGSPG------------------------PTGRPGVTGID 622

Query: 819 HCLSQHGSPGIPGPPGPIGPE---------GPRGLPGLPGRDGVPGLVGVPGRPGVRGLK 869
                 G+ G PG PGP G +         GP+GL G PG  G PG  G+PG PG  G  
Sbjct: 623 GAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPL 682

Query: 870 GLPGRNGEKGSQGF-GYPGEQGPPGPPGPEGPPGIS-------KEGPPGDPGLPGKDGDH 921
           G PG  G  G +G  G PG  GPPG PGP G  G S       ++G  G+ G PG  GD 
Sbjct: 683 GHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDV 742

Query: 922 GKPGIQGQPGPPG 934
           G  G QG+PG PG
Sbjct: 743 GLKGDQGKPGAPG 755



 Score =  207 bits (528), Expect = 3e-53
 Identities = 126/290 (43%), Positives = 143/290 (49%), Gaps = 22/290 (7%)

Query: 424  PGFNGECLNGPS-DVG----STPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKP 478
            PG  G  + GP  D+G    S P+    PPGK G  G  G  G  G  G PG  G  G P
Sbjct: 1216 PGAPG--IPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDP 1273

Query: 479  GYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAK 538
            G  GI G+PG  G PG  G  G PG  GEPG  G  G RG  G  G  G  G KG  G  
Sbjct: 1274 GVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEP 1333

Query: 539  GDKGSPGFYGKKGAKGEKGNA---GFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP 595
            G  G PG  G  GA+G  G     G  G+PGP GEPG  G  G MG PG  G +G PG  
Sbjct: 1334 GPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLK 1393

Query: 596  GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSK 655
            G  G +GE         +G +G  G IGPPG+ G+KG  G+PG+ G  G  G PG PG  
Sbjct: 1394 GDTGPKGE---------KGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPI 1444

Query: 656  GSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGE 705
            GS G P   G PG +G  G+ G+ GSPG  G  G  G  G  G  G   E
Sbjct: 1445 GSLGHP---GPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAE 1491



 Score =  145 bits (365), Expect = 2e-34
 Identities = 105/278 (37%), Positives = 127/278 (45%), Gaps = 55/278 (19%)

Query: 703 QGEKGIQGQKGENGRQG-IPGQQGIQGHHGAKGERGEKGEPGV-------RGAIGSKGES 754
           + E+G     G + R    P +   Q   GA GE+G KGEP V        G  G+ G  
Sbjct: 342 EDEEGDDSTMGPDFRAAEYPSRTQFQIFPGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQ 400

Query: 755 GVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGRE---------------FSEQFIRQVCTD 799
           GV G  GP GP G PGDPGP GP GL G PG +               F+    +     
Sbjct: 401 GVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVS 460

Query: 800 VIRAQLPVLLQSGRIRNCDHCLSQHGSPG---IPGPPGPIG------------PEGPRGL 844
             +AQ   +LQ  +       LS  G PG   + G PGP+G             EGP+G 
Sbjct: 461 FQQAQAQAVLQQTQ-------LSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGP 513

Query: 845 PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGP 900
            GL G  G PG VG  GRPG  G +GLPG  G KG +GF    G PGE+G  G  G  G 
Sbjct: 514 RGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQ 573

Query: 901 PGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
           PG     PPG+ G  G +G  G  G  G+PGP G+  P
Sbjct: 574 PG-----PPGEDGERGAEGPPGPTGQAGEPGPRGLLGP 606


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  385 bits (989), Expect = e-106
 Identities = 226/552 (40%), Positives = 277/552 (50%), Gaps = 78/552 (14%)

Query: 448  PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
            PG PG+ G +G PGL GNPG  G PG  G PG  G  G  G  G PG +G +GL G  GE
Sbjct: 789  PGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGE 848

Query: 508  PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP 567
            PG  GDKG++G+PG  G  G  G KG  G  G  G+ G  G  G  G+KG+ GFPG PGP
Sbjct: 849  PGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGP 908

Query: 568  AG------EPGRHGKDGLMGSPGFKG------------EAGSPGAPGQDGTRGEPGIPGF 609
             G       PG +G +G+ G PG +G            + G  G PG  G  G+PG  GF
Sbjct: 909  EGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGF 968

Query: 610  PGNRGLMGQKGEIGPPGQQGKKGAPGM---------PGLMGSNGSPGQPGTPGSKGSKGE 660
            PG  GL G KGE G PG+ G  G  G          PG++G  G  G  G PG  G KG 
Sbjct: 969  PGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGS 1028

Query: 661  PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKG------NQGEKGIQGQKGE 714
             G  GMPG  G  GEPG  G PG  G  G+ G +G++G +G       QG +G++G  G 
Sbjct: 1029 MGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGP 1088

Query: 715  NGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGP 774
             GR G PGQQG+ G  G  G RG  G PG  G  G+KG  G  G  GP GP G PG+ GP
Sbjct: 1089 QGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148

Query: 775  QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPG 834
            +GPPG  G+PG               ++  L  L   G        + Q G PG+ G  G
Sbjct: 1149 KGPPGAVGEPGLPGEAG---------MKGDLGPLGTPGE----QGLIGQRGEPGLEGDSG 1195

Query: 835  PIGPEGPRGLPGLPGRD---------GVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG--- 882
            P+GP+G +G  G PG D         G+ G  G PG PGV G++G  G++G++G +G   
Sbjct: 1196 PMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTG 1255

Query: 883  -------------FGYPGEQGPPGPPGPEGPPGI-------SKEGPPGDPGLPGKDGDHG 922
                          G PG+ GPPG PGP+G  G         + G  G+PGL G DG  G
Sbjct: 1256 AKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKG 1315

Query: 923  KPGIQGQPGPPG 934
              G  G PGP G
Sbjct: 1316 IVGPLGPPGPKG 1327



 Score =  384 bits (986), Expect = e-106
 Identities = 238/572 (41%), Positives = 280/572 (48%), Gaps = 93/572 (16%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PG  G       D G    P +   G PG QG KG  GLPG PG  G+PG  GK G +G 
Sbjct: 849  PGLKG-------DKGEQGVPGVS--GDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGS 899

Query: 484  AGTPGVPGSPGIQG------------------ARGLPGYKGEPGRDGDKGDRGLPGFPGL 525
             G PG PG  G  G                  ARGLPG +G+ G +GD+G  G PG PGL
Sbjct: 900  IGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGL 959

Query: 526  HGMPGSK---GEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGS 582
             G PG K   G  G  G KG PG  G+ G  GE+G  GF GL G  G  G  G  G+MG 
Sbjct: 960  EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGP 1019

Query: 583  PGF---KGEAGSPGAPGQDGTRGEPGIPGFPGNR---------------------GLMGQ 618
            PG    KG  G PG PG  GT GEPG  G PG+R                     G  G 
Sbjct: 1020 PGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGS 1079

Query: 619  KGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGA 678
            +G  GPPG QG+ G PG  G+ G  G  G  G PG  G  G PG +G+PG  G +G  G 
Sbjct: 1080 RGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGP 1139

Query: 679  TGSPGE------PGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGA 732
             G PGE      PG +G PG+ G+ G KG+ G  G  G++G  G++G PG +G  G  G 
Sbjct: 1140 IGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGP 1199

Query: 733  KGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQF 792
             G +G++G+PG  G  G KG+ G+ G  GP GP G  G  GP+G  G  G+ GR  ++  
Sbjct: 1200 DGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAK-- 1257

Query: 793  IRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPE------GPRGLPG 846
                                  +     L + G PG PGPPG  GP+      GP G PG
Sbjct: 1258 --------------------GAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPG 1297

Query: 847  LPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPG-ISK 905
              G  G PGL G  G  G+ G  G PG  GEKG QG     E GPPGPPG  GP G    
Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAE-GPPGPPGDRGPVGDRGD 1356

Query: 906  EGPPGDPGLPGKDGD---HGKPGIQGQPGPPG 934
             G PGDPG PG++G     GKPG QGQPG PG
Sbjct: 1357 RGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPG 1388



 Score =  378 bits (971), Expect = e-104
 Identities = 247/598 (41%), Positives = 291/598 (48%), Gaps = 93/598 (15%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICP--PGKPGLQGPKGDPGL---------------PGN 465
            +PG  G  + G       P P   P  PG PG +G KGDPGL               PG 
Sbjct: 641  LPGLPG--IPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGL 698

Query: 466  PGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQG---ARGLPGYKGEPGRDGD---KGDRGL 519
             G PG PG+ G  GY G AG PG  G PG +G   A+G PG +G PG  GD   KG RG 
Sbjct: 699  SGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGY 758

Query: 520  PGFPGLHGMPGSKGEMGAKGDKGS---------PGFYGKKGAKGEKGNAGFPGLPGPAGE 570
             G PGL G+PGS GE G  G  G          PG +G++G  G  GN G  GLPGP G 
Sbjct: 759  IGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGV 818

Query: 571  PGRHGKDGLMGSPGF------KGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGP 624
            PG  G  G++G  G+      KG  GS G PG  G +GE G+PG  G+ G  G KG  G 
Sbjct: 819  PGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGL 878

Query: 625  PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGE 684
            PG  G +G PG  G +G  GS G PG PG +G  G+ G  G  G  G+KG+PGA G PG 
Sbjct: 879  PGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGP 938

Query: 685  PGYMG------------LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG- 731
             G +G             PG++G+ G KG  G  G+ G KGE G  G PG  G QG  G 
Sbjct: 939  RGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGF 998

Query: 732  -----------AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGL 780
                        KG+RG  G PGV G  GS G  G+ G MG  G  G  G PG +GPPG+
Sbjct: 999  IGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGM 1058

Query: 781  DGKPGR-----------EFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI 829
             G  GR           E   + ++       R   P   Q G      H L   G PGI
Sbjct: 1059 RGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG--QQGVAGERGH-LGSRGFPGI 1115

Query: 830  PGP------------PGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGE 877
            PGP            PGP GP+GP G PG  G  G PG VG PG PG  G+KG  G  G 
Sbjct: 1116 PGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGT 1175

Query: 878  KGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
             G QG  G  GE G  G  GP GP G+  +G  GDPG  G+ G+ G+ G+ G+ GPPG
Sbjct: 1176 PGEQGLIGQRGEPGLEGDSGPMGPDGL--KGDRGDPGPDGEHGEKGQEGLMGEDGPPG 1231



 Score =  377 bits (967), Expect = e-104
 Identities = 223/516 (43%), Positives = 260/516 (50%), Gaps = 54/516 (10%)

Query: 438  GSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQG 497
            GSTP P +  P  PG +G  G PG PG PG PG PG  G  G  G  G PG+PG PG +G
Sbjct: 616  GSTPFPLLMGP--PGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKG 673

Query: 498  ARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKG 557
             +G PG       DG KGD GLPG  G  G PG KG  G  G  G PG  G+ G +G  G
Sbjct: 674  QKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPG 733

Query: 558  NAGFP---GLPGPAGEPGRHGKDGLMGSPGFKGEAGSP---GAPGQDGTRGEPGIPGFPG 611
              G+P   GLPGP G+PG  G  G +G PG  G  GS    G PG  G RG+ G+PGFPG
Sbjct: 734  AKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPG 793

Query: 612  NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASG 671
              G  G  G  G PG+ G  G PG+PGL+G  G  G  G PG KG KG  G  G PG  G
Sbjct: 794  VFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKG 853

Query: 672  LKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG 731
             KGE G  G  G+PG+ G  G QG  G  G +G+ G  G+ G+ G  G PG  G +G   
Sbjct: 854  DKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGF-- 911

Query: 732  AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQ 791
                 G+ G PG  G  G KG+ G  GL GP G  G  GD GP GPPG  G  G+   + 
Sbjct: 912  ----PGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKG 967

Query: 792  FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGL------P 845
            F  +   D ++                      G PG PG PGP+G +G  G       P
Sbjct: 968  FPGRPGLDGVK----------------------GEPGDPGRPGPVGEQGFMGFIGLVGEP 1005

Query: 846  GLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGI-- 903
            G+ G  G  G++G PG PG +G  G PG  G     G G PGE GP GPPG  GPPG+  
Sbjct: 1006 GIVGEKGDRGMMGPPGVPGPKGSMGHPGMPG-----GMGTPGEPGPQGPPGSRGPPGMRG 1060

Query: 904  -----SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                    GP G  G  G  G  G PG QG+PG PG
Sbjct: 1061 AKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG 1096



 Score =  373 bits (957), Expect = e-103
 Identities = 232/544 (42%), Positives = 276/544 (50%), Gaps = 37/544 (6%)

Query: 424  PGFNGEC-LNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            PG  G+C L GP  +   P       G PG +GP+G PG  GNPG PG PG  G+ G  G
Sbjct: 627  PGPKGDCGLPGPPGLPGLP-------GIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPG 679

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAK---G 539
            ++      G+ G  G  GL G  G PGR G KG  G  G PG  G PG +G  GAK   G
Sbjct: 680  LSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPG 739

Query: 540  DKGSPGFYGKKGAKGEKGNAGFP---GLPGPAGE---PGRHGKDGLMGSPGFKGEAGSPG 593
             +G PG  G  G KG +G  G P   GLPG  GE   PG  GK G MG PGF G  G  G
Sbjct: 740  RQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERG 799

Query: 594  APGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM------PGLMGSNGSPG 647
             PG DG  GE G+PG PG  GL+G  G +GP G  G KG  G+      PGL G  G  G
Sbjct: 800  PPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQG 859

Query: 648  QPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKK---GDKGNQG 704
             PG  G  G +G+ G QG+PG  G +G+PG  G  G+ G +G PG  G +   GD G  G
Sbjct: 860  VPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPG 919

Query: 705  EKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAG 764
            + G +G KG+ G +G+PG +G  G  G +G  G  G PG+ G  G KG  G  GL G  G
Sbjct: 920  DNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKG 979

Query: 765  PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQH 824
              G PG PGP G  G  G  G       + +     +     V    G + +        
Sbjct: 980  EPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGH-PGMPGGM 1038

Query: 825  GSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLP---GRNGEKGSQ 881
            G+PG PGP GP G  GP G+ G  GR G  G  G  G  G RGLKG P   GR G  G Q
Sbjct: 1039 GTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQ 1098

Query: 882  GF----GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG-IC 936
            G     G+ G +G PG PGP GPPG   +G PG+PG  G  G  G PG  G  GPPG + 
Sbjct: 1099 GVAGERGHLGSRGFPGIPGPSGPPG--TKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVG 1156

Query: 937  DPSL 940
            +P L
Sbjct: 1157 EPGL 1160



 Score =  368 bits (944), Expect = e-101
 Identities = 226/532 (42%), Positives = 270/532 (50%), Gaps = 62/532 (11%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
            P G+ G +G KG PG  G PG PGQ G  G+ G+ G  G PG+PG  G  G +GLPG   
Sbjct: 1073 PAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPG--- 1129

Query: 507  EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
            EPG  G +G  G PG  G  G PG+ GE G  G+ G  G  G  G  GE+G  G  G PG
Sbjct: 1130 EPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPG 1189

Query: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPG 626
              G+ G  G DGL G  G  G  G  G  GQ+G  GE G PG PG  G+ G +G+ G  G
Sbjct: 1190 LEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQG 1249

Query: 627  QQGKKGAPGMPGL------MGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATG 680
            ++G+ GA G  G       MG  G PG PGTPG KGS+G  G  G PG  G +GEPG  G
Sbjct: 1250 EKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAG 1309

Query: 681  SPGEPGYMGLPGIQGKKGDKGNQGEKGI----------------QGQKGENGRQGIPGQQ 724
              G  G +G  G  G KG+KG QGE G                 +G +GE G  G PGQ+
Sbjct: 1310 YDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQE 1369

Query: 725  GIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKP 784
            G+QG  G  G++G+ G PG RG  G KG  G +G   P G +G+ G PG +G  GL G P
Sbjct: 1370 GVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEG---PKGKQGKAGAPGRRGVQGLQGLP 1426

Query: 785  GREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGL 844
            G        R V   V R  L  +     +   D    Q G  G  G PGP+GP G RG 
Sbjct: 1427 GP-------RGV---VGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGN 1476

Query: 845  PGLPG------------RDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-------FGY 885
            PG+ G              G+PG +G PG+ G  G  GLPG  GE GS+G        G+
Sbjct: 1477 PGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGF 1536

Query: 886  PGEQ---GPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            PG     GP GPPG  G  GI  +GP G PGL GK+G  G  GI G  G PG
Sbjct: 1537 PGMAGLFGPKGPPGDIGFKGI--QGPRGPPGLMGKEGIVGPLGILGPSGLPG 1586



 Score =  365 bits (937), Expect = e-100
 Identities = 238/612 (38%), Positives = 283/612 (46%), Gaps = 123/612 (20%)

Query: 424  PGFNG-ECLNGPSDVGSTPAPC-----------ICPPGKPGLQGPKGDPGLPGNPGY--- 468
            PG NG E + G       P P            + PPG PGL+G  G  G PG PG    
Sbjct: 918  PGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGV 977

Query: 469  ---PGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGL 525
               PG PG+ G  G QG  G  G+ G PGI G +G  G  G PG  G KG  G PG PG 
Sbjct: 978  KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037

Query: 526  HGMPGSKGEMGAKGDKGSPGFYGKKGAKG---------EKGNAGFPGLPGPAGEPGRHGK 576
             G PG  G  G  G +G PG  G KG +G         E+G+ G  G PGP G PGR G+
Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ 1097

Query: 577  DGLMGSPGFKGEAGSPGAPGQDG---TRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGA 633
             G+ G  G  G  G PG PG  G   T+G PG PG  G +G +G  GE+GP G  G  G 
Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGE 1157

Query: 634  PGMPGLMGSNGSPGQPGTPGSKG---SKGEPGIQG------------------------M 666
            PG+PG  G  G  G  GTPG +G    +GEPG++G                         
Sbjct: 1158 PGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGE 1217

Query: 667  PGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGI 726
             G  GL GE G  G PG  G  G  G  GK+G+KG  G KG +G +G+ G  G+PG  G 
Sbjct: 1218 KGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGP 1277

Query: 727  QGHHGAKGERGEKGEPGVRGAIGSKGESGVDGL---------MGPAGPKGQ--------- 768
             G  G KG RG  G  G  G +G++GE G+ G          +GP GPKG+         
Sbjct: 1278 PGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGK 1337

Query: 769  ----PGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQH 824
                PG PG +GP G  G  G      +  Q     +R +                  Q 
Sbjct: 1338 AEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKP----------------GQQ 1381

Query: 825  GSPGIPGP---PGPIG------PEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGL---- 871
            G PG PGP   PGP G      P+G +G  G PGR GV GL G+PG  GV G +GL    
Sbjct: 1382 GQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIA 1441

Query: 872  -----PGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGI 926
                 PGR+G+ G QG     EQG  G PGP GP G  K G PG  GLPG  G    PG 
Sbjct: 1442 GPDGLPGRDGQAGQQG-----EQGDDGDPGPMGPAG--KRGNPGVAGLPGAQGP---PGF 1491

Query: 927  QGQPGPPGICDP 938
            +G+ G PG   P
Sbjct: 1492 KGESGLPGQLGP 1503



 Score =  354 bits (909), Expect = 2e-97
 Identities = 209/499 (41%), Positives = 261/499 (52%), Gaps = 46/499 (9%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK------PGYQGIAGT---PGVPGSPGIQG 497
            P G PG  GPKG PG  G PG PG+ G  G       PG QG+ G    PG+ G  G  G
Sbjct: 1139 PIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMG 1198

Query: 498  ARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKG 557
              GL G +G+PG DG+ G++G  G  G  G PG  G  G +G +G  G  G+KG  G KG
Sbjct: 1199 PDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKG 1258

Query: 558  NAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMG 617
              G+ G  G  G PG  G  G  G  G +G  G  GAPG+ G +GEPG+ G+ G++G++G
Sbjct: 1259 AKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVG 1318

Query: 618  QKGEIGPPGQQGKKGAPGMPGLM-GSNGSPGQPGTPGSKGSKGEPGIQGMPG---ASGLK 673
                +GPPG +G+KG  G  G   G  G PG  G  G +G +GEPG  G PG     GL+
Sbjct: 1319 P---LGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLR 1375

Query: 674  GEPGATGSPGEPGYMGLPGIQGKKG---DKGNQGEKGIQGQKGENGRQGIPGQQGIQGHH 730
            G+PG  G PG PG  G PG +G KG    KG QG+ G  G++G  G QG+PG +G+ G  
Sbjct: 1376 GKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQ 1435

Query: 731  GAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSE 790
            G +G  G  G PG  G  G +GE G DG  GP GP G+ G+PG  G PG  G PG +   
Sbjct: 1436 GLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGES 1495

Query: 791  QFIRQVCTDVIRAQ-----LPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP------- 838
                Q+     R       LP        +       + G PG+ G  GP GP       
Sbjct: 1496 GLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFK 1555

Query: 839  --EGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPG 896
              +GPRG PGL G++G+ G +      G+ G  GLPG  G+KGS+G    G QGP GPPG
Sbjct: 1556 GIQGPRGPPGLMGKEGIVGPL------GILGPSGLPGPKGDKGSRGDW--GLQGPRGPPG 1607

Query: 897  PEGPPGISKEGPPGDPGLP 915
            P G P     GPPG PG P
Sbjct: 1608 PRGRP-----GPPGPPGGP 1621



 Score =  276 bits (707), Expect = 5e-74
 Identities = 161/377 (42%), Positives = 197/377 (52%), Gaps = 17/377 (4%)

Query: 414  QNNRETACEIPGFNGEC--LNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQ 471
            +  R  A    G+ G+   +  P D G    P   P G  G  GP G PG  G  G PG 
Sbjct: 1250 EKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPG--PKGSRGSLGPTGAPGRMGAQGEPGL 1307

Query: 472  PGQDGKPGYQGIAGTPGVPGSPGIQG----ARGLPGYKGEPGRDGDKGDRGLPG---FPG 524
             G DG  G  G  G PG  G  G QG    A G PG  G+ G  GD+GDRG PG   +PG
Sbjct: 1308 AGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPG 1367

Query: 525  LHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPG 584
              G+ G +G+ G +G  G PG  G  G KG KG  G  G  G AG PGR G  GL G PG
Sbjct: 1368 QEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPG 1427

Query: 585  FKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNG 644
             +G  G  G  G  G  G PG  G  G +G  G  G+ GP G  GK+G PG+ GL G+ G
Sbjct: 1428 PRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQG 1487

Query: 645  SPG---QPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKG 701
             PG   + G PG  G  G+ G +G  G  G +GEPG+ G PG+ G MG PG+ G  G KG
Sbjct: 1488 PPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKG 1547

Query: 702  NQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMG 761
              G+ G +G +G  G  G+ G++GI G  G  G     G PG +G  GS+G+ G+ G  G
Sbjct: 1548 PPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGP---SGLPGPKGDKGSRGDWGLQGPRG 1604

Query: 762  PAGPKGQPGDPGPQGPP 778
            P GP+G+PG PGP G P
Sbjct: 1605 PPGPRGRPGPPGPPGGP 1621



 Score =  110 bits (276), Expect = 5e-24
 Identities = 67/156 (42%), Positives = 82/156 (52%), Gaps = 15/156 (9%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PGF GE    P  +G        PPGK G +G  G PG  G PG  GQPG  G+ G+ G+
Sbjct: 1489 PGFKGES-GLPGQLG--------PPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGM 1539

Query: 484  AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
            AG  G  G PG  G +G+ G +G PG  G +G  G  G  G  G+PG KG      DKGS
Sbjct: 1540 AGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKG------DKGS 1593

Query: 544  PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGL 579
             G +G +G +G  G  G PG PGP G P +  +D L
Sbjct: 1594 RGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDL 1629


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  385 bits (988), Expect = e-106
 Identities = 240/576 (41%), Positives = 287/576 (49%), Gaps = 90/576 (15%)

Query: 433 GPSDVGSTPAP--CICPPGKPGLQGP------KGDPGLPGNPGYPGQPGQDGKPGYQGIA 484
           GP+    T  P     PPG PG QG       +G PG PG PG+ G+ G  G+PG  GI 
Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQ 491

Query: 485 GTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSP 544
           G  G PG  G +G RG PG  G PG  G++G  G  GFPG  G+PG KG   A+G++G  
Sbjct: 492 GPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG---AQGERGPV 548

Query: 545 GFYGKKGAKGEKGNAGFPGLPG------------------PAGEPGRHGKDGLMGSPGFK 586
           G  G KG++G+ G  G PGLPG                  P G PG  G+ G  GS G +
Sbjct: 549 GSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIR 608

Query: 587 GEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGE------------IGPPGQQGKKGAP 634
           G+ GS G PG  G+ G+PG PG  GN G+ GQ+G             +GPPG  G++G  
Sbjct: 609 GQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQ 668

Query: 635 GMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQ 694
           G PG  G  G PG PG PG  G  G+ G+ G PGA G  G  G  G+PGE G  G+ G+ 
Sbjct: 669 GPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLP 728

Query: 695 GKKG---------DKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVR 745
           G+KG          KG+ G  G  G  G  G QG+PG++GI G  G KG+RG  GE G  
Sbjct: 729 GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAE 788

Query: 746 GAIGSKGESGVDGLMGP---AGPKGQPGDPGPQG---PPGLDGKPGREFSEQFIRQVCTD 799
           G  G+ G  G+ G +GP   AGP G+ G+PGP+G   PPG  G PG            T 
Sbjct: 789 GTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENG-----PTG 843

Query: 800 VIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGV 859
            +    P        +  D      G PG PG  G  G  GP+GL G PG  G  G   V
Sbjct: 844 AVGFAGP--------QGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNG---V 892

Query: 860 PGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPPG---DPGL- 914
           PG  G RG +G PG  G  GS G  G PG  G PGP GP G PG  KEGPPG   DPG  
Sbjct: 893 PGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPG--KEGPPGLRGDPGSH 950

Query: 915 -----------PGKDGDHGKPGIQGQPGPPGICDPS 939
                      PG  GD G PG  GQPGP G   P+
Sbjct: 951 GRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPA 986



 Score =  382 bits (981), Expect = e-106
 Identities = 244/582 (41%), Positives = 289/582 (49%), Gaps = 94/582 (16%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PG +GE   GPS     P       G+ G QGP G  G  G PG PG PG+ GKPG QG+
Sbjct: 644  PGKDGEV--GPSGPVGPPGLA----GERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGV 697

Query: 484  AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGF--------------------- 522
             G PG  G  G +G RG PG +GEPG  G  G++G+ G                      
Sbjct: 698  PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGP 757

Query: 523  PGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGS 582
            PGL GMPG +G  G  G KG  G  G+KGA+G  GN G  GLPGP G PG  G  G  G 
Sbjct: 758  PGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE 817

Query: 583  PGFKGEAGSPGAPGQDGTRGE---PGIPGFPGNRGLMGQ---KGEIGPPGQQGKKGAPGM 636
            PG +G  G PG+ G  G+RGE    G  GF G +G  GQ   KGE G PGQ+G  G+PG 
Sbjct: 818  PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP 877

Query: 637  PGLMGS---NGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPG------EPGY 687
             GL GS   +G  G PG  G +G++G PG  G PG++G  G PG  G+PG      EPG 
Sbjct: 878  QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGK 937

Query: 688  MGLPGIQGKKG------------------DKGNQGEKGIQGQKGENGRQGIPGQQGIQGH 729
             G PG++G  G                  DKG+ GE G  G  G  G  G  GQ+GI G 
Sbjct: 938  EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGM 997

Query: 730  HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG------DPGPQGPPGLDGK 783
             G +GERG  G PG  G  G  G +G  G  GP GP G PG      +PGP+GP G DG 
Sbjct: 998  PGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGT 1057

Query: 784  PGRE--FSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP 841
            PGR+    E+  R    D   A LP                  G+PG PGP G  G  G 
Sbjct: 1058 PGRDGAVGERGDRG---DPGPAGLP---------------GSQGAPGTPGPVGAPGDAGQ 1099

Query: 842  RGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGP 897
            RG PG  G  G PG  G  G PG +G +G  G +G++G +G     G+ G QG PGPPGP
Sbjct: 1100 RGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP 1159

Query: 898  EGPPGIS----KEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
             G  G +      GP G PG  G  G  G PG  G  GPPG+
Sbjct: 1160 NGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGV 1201



 Score =  379 bits (974), Expect = e-105
 Identities = 221/509 (43%), Positives = 250/509 (49%), Gaps = 58/509 (11%)

Query: 448  PGKPGLQGPKG---DPGLPG---NPGYPGQ---PGQDGKPGYQGIAGTPGVPGS------ 492
            PG  GL GPKG   DPG PG   N G PGQ   PG+DG+ G  G  G PG+ G       
Sbjct: 611  PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP 670

Query: 493  PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFY---GK 549
            PG  G +GLPG  G PG  G  GD+G+PG PG  G  G +GE G  G++G PG     G+
Sbjct: 671  PGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGE 730

Query: 550  KGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGF 609
            KG  G  G  G  G PGP+G PG  G  GL G PG +G AG+PG  G  G  GE G  G 
Sbjct: 731  KGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGT 790

Query: 610  PGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA 669
             GN G  G  G +GPPG  G  G  G PG  G  G PG  G PGS+G  G  G  G  G 
Sbjct: 791  AGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGP 850

Query: 670  SGLKGEPGATGSPGEPGY---MGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGI 726
             G  G+PG  G PGEPG     G PG QG  G  G  G  G+ G KG  G QG PG  G 
Sbjct: 851  QGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGF 910

Query: 727  QGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGR 786
             G  G  G  G  G PG  G +G  G+ G  GL G  G  G+ GD GP GPPG  G  G 
Sbjct: 911  PGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD 970

Query: 787  EFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPG 846
                                                + G PG  GPPGP G  G RG+ G
Sbjct: 971  P----------------------------------GEDGQPGPDGPPGPAGTTGQRGIVG 996

Query: 847  LPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISK 905
            +PG+ G  G+ G+PG  G  G  G  G  G+KG  G  G PG  GP G PGPEGP G   
Sbjct: 997  MPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAG--N 1054

Query: 906  EGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            +G PG  G  G+ GD G PG  G PG  G
Sbjct: 1055 DGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083



 Score =  377 bits (969), Expect = e-104
 Identities = 220/515 (42%), Positives = 266/515 (51%), Gaps = 69/515 (13%)

Query: 447 PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
           PPG+PG  GP G  G  G  G PG+PG+DG+PG  G  G  G  GSPG   ARG PG  G
Sbjct: 238 PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPG---ARGFPGAPG 294

Query: 507 EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
            PG  G +G +GL G  G  G PGSKGE G  G  G+ G  G +G  GE+G  G  G PG
Sbjct: 295 LPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPG 354

Query: 567 PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPG 626
             G  G  GK G MG  G  G +G PG PG    +GE G  G  G  G  GQ+GE GPPG
Sbjct: 355 QRGAHGMPGKPGPMGPLGIPGSSGFPGNPGM---KGEAGPTGARGPEGPQGQRGETGPPG 411

Query: 627 QQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPG 686
             G   +PG+PG +G++G+PG  G  GS G+ G PG  G PG+ G +G  G  G  G+PG
Sbjct: 412 PVG---SPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPG 468

Query: 687 YMGLPGIQGKKGDKGNQGEKGIQG------QKGENGRQGIPGQQGIQGHHGAKGERGEKG 740
             G+PG +G+ G KG  G  GIQG      ++G+ G +G PG  G  G  G +G  G +G
Sbjct: 469 DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRG 528

Query: 741 EPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDV 800
            PG  G  G KG  G  G +G +GPKG  GDPG  G PGL G  G               
Sbjct: 529 FPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLT------------- 575

Query: 801 IRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPP---GPIGPEGPRGLPGLPGRDGVPGLV 857
                                   G+PG+ GP    GP+G  G  G PG PG  G+ G  
Sbjct: 576 ------------------------GNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQP 611

Query: 858 GVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGPPGIS----KEGPP 909
           G  G PG +G  G PG+ GE G+ G     G PG+ G  GP GP GPPG++    ++GPP
Sbjct: 612 GSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPP 671

Query: 910 GD------PGLPGKDGDHGKPGIQGQPGPPGICDP 938
           G       PG PG  G+ GKPG QG PG PG   P
Sbjct: 672 GPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGP 706



 Score =  377 bits (968), Expect = e-104
 Identities = 231/565 (40%), Positives = 272/565 (48%), Gaps = 71/565 (12%)

Query: 424 PGFNGECLNGPSDV----------GSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPG 473
           PG  GE   GP+            G T  P   P G PGL G  G  G PG  G  G PG
Sbjct: 383 PGMKGEA--GPTGARGPEGPQGQRGETGPPG--PVGSPGLPGAIGTDGTPGAKGPTGSPG 438

Query: 474 QDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKG 533
             G PG  G  G+PG  GS G QG RG PG  G PG  G+ G +G PG  G+ G  G  G
Sbjct: 439 TSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPG 498

Query: 534 EMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPG 593
           E G +G +G PG  G  G  GE+G  G  G PG  G PG  G  G  G  G  G  GS G
Sbjct: 499 EEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQG 558

Query: 594 APGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPG 653
            PG+ G  G PG  G  GN G+ G +G++GP G  G+ G PG PG +G  G PG  G PG
Sbjct: 559 DPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPG 618

Query: 654 SKGSKGEPGIQGMPGASGLKGEPGATGSPGE---PGYMGLPGIQGKKGDKGNQGEKGIQ- 709
            KGS G+PG  G  G +G+ G+ GA G  GE    G +G PG+ G++G++G  G  G Q 
Sbjct: 619 PKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQG 678

Query: 710 --------GQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMG 761
                   G+ G+ G QG+PG  G  G  G +GERG  GE G  G  G  GE G+ G  G
Sbjct: 679 LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHG 738

Query: 762 PAGPKGQP---GDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSG-RIRNC 817
           P GPKG P   G PG  GPPGL G PG              +     P   + G   +  
Sbjct: 739 PDGPKGSPGPSGTPGDTGPPGLQGMPGER-----------GIAGTPGPKGDRGGIGEKGA 787

Query: 818 DHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVR----------- 866
           +      G+ G+PGP GP GP GP G  G PG  G+ G  G  G PG R           
Sbjct: 788 EGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGF 847

Query: 867 ----------GLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGI-------SKEGPP 909
                     G+KG PG  G+KG    G PG QG  G PGP GP G+         +GPP
Sbjct: 848 AGPQGPDGQPGVKGEPGEPGQKGDA--GSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPP 905

Query: 910 GDPGLPGKDGDHGKPGIQGQPGPPG 934
           G  G PG  G  G PG  G PGP G
Sbjct: 906 GATGFPGSAGRVGPPGPAGAPGPAG 930



 Score =  366 bits (940), Expect = e-101
 Identities = 219/523 (41%), Positives = 256/523 (48%), Gaps = 70/523 (13%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPG------------VPGSPGIQ 496
            G  G  GPKG PG  G PG  G PG  G PG +GIAGTPG              G+ G  
Sbjct: 735  GGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGND 794

Query: 497  GARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKG-------------- 542
            GARGLPG  G PG  G  G++G PG  GL G PGS+G  G++G+ G              
Sbjct: 795  GARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPD 854

Query: 543  -SPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGA---PGQD 598
              PG  G+ G  G+KG+AG PG  G AG PG HG +G+ G  G +G  G PGA   PG  
Sbjct: 855  GQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSA 914

Query: 599  GTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSK 658
            G  G PG  G PG  G +G+ G+ GPPG +G  G+ G  G  G  G PG PG  G  G  
Sbjct: 915  GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGED 974

Query: 659  GEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQ 718
            G+PG  G PG +G  G+ G  G PG+ G  G+PG+ G  G  G  G  G  G KG  G  
Sbjct: 975  GQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPV 1034

Query: 719  GIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPP 778
            G PG  G  G  G +G  G  G PG  GA+G +G+ G  G  G  G +G PG PGP G P
Sbjct: 1035 GPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAP 1094

Query: 779  GLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP 838
            G  G+ G   S   I                               G PG  G  G  GP
Sbjct: 1095 GDAGQRGDPGSRGPI-------------------------------GPPGRAGKRGLPGP 1123

Query: 839  EGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPE 898
            +GPRG  G  G  G  G  G  G  G++GL G PG NGE+GS G   PG  GP GPPGP 
Sbjct: 1124 QGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGI--PGPFGPRGPPGPV 1181

Query: 899  GPPG-------ISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            GP G       +   GPPG  G  G+ G  G PG  G PGPPG
Sbjct: 1182 GPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPG 1224



 Score =  365 bits (938), Expect = e-101
 Identities = 220/509 (43%), Positives = 256/509 (50%), Gaps = 49/509 (9%)

Query: 448 PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
           PGKPG  GP G PG  G PG PG  G+ G  G +G  G  G  G  G  G  G PG  G 
Sbjct: 362 PGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421

Query: 508 PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP 567
            G DG  G +G  G PG  G PGS G  G+ G +GS G  G +G  G+ G  GF G  GP
Sbjct: 422 IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGP 481

Query: 568 AGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQ 627
            GEPG HG  G +G PG +G+ G  G PG  G  G  G  G PGNRG  G  G  GP G 
Sbjct: 482 KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGA 541

Query: 628 QGKKGAPGMPGLMGSNGS---PGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGE 684
           QG++G  G  G  GS G    PG+PG PG++G  G PG+QG  G  G  G PG  G PG 
Sbjct: 542 QGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGP 601

Query: 685 PGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGV 744
           PG +G+ G  G  G  G +G  G  G+ GE G  G+PGQ+G  G  G  G  G  G PG+
Sbjct: 602 PGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGL 661

Query: 745 ---RGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVI 801
              RG  G  G +G  GL GP GP G+ G PG QG PG  G  G                
Sbjct: 662 AGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVG---------------- 705

Query: 802 RAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGP------IGPEGPRGLP---GLPGRDG 852
                 L   G   N      + G PGI G PG        GP+GP+G P   G PG  G
Sbjct: 706 -----PLGPRGERGN----PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTG 756

Query: 853 VPGLVGVPGRPGVRGL---KGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGPPGISK 905
            PGL G+PG  G+ G    KG  G  GEKG++G     G  G  GP GPPGP GP G  +
Sbjct: 757 PPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTG--E 814

Query: 906 EGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           +G PG  GL G  G  G PG +G+ GP G
Sbjct: 815 KGEPGPRGLVGPPGSRGNPGSRGENGPTG 843



 Score =  361 bits (926), Expect = 2e-99
 Identities = 225/531 (42%), Positives = 261/531 (49%), Gaps = 63/531 (11%)

Query: 447 PPGKPGLQGPKG---DPGLPGNPGYPGQPGQDGKPGYQGI--------AGTPG------- 488
           P G+PG +GP+G   +PG+PG PG PG PG    PG  G+        AG          
Sbjct: 148 PKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQ 207

Query: 489 ---VPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPG 545
              +PGS G  G RG  G +G+ G  G  G  G PG PG  G  GS+G  G  G  G  G
Sbjct: 208 VGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDG 267

Query: 546 FYGKKGAKGEKGNAGFPG---LPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG 602
             G+ G  GE G AG PG    PG  G PG  G  G  G  G KGE G+PG+ G+ G  G
Sbjct: 268 EPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTG 327

Query: 603 EPGIPGFPGNRGLMGQKGEIGP---PGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKG 659
             G  G  G RG+ G++G +GP   PGQ+G  G PG PG MG  G PG  G PG+ G KG
Sbjct: 328 PMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKG 387

Query: 660 EPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQG 719
           E G  G  G  G +G+ G TG PG  G  GLPG  G  G  G +G  G  G  G  G  G
Sbjct: 388 EAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAG 447

Query: 720 IPGQQGIQGHHGAKGERGEKGEPGV---RGAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776
            PG  G QG  G +G RG+ G+PGV   +G  G KGE G  G+ GP GP G+ G  GP+G
Sbjct: 448 PPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRG 507

Query: 777 PPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI 836
            PG  G PG                    PV       R         GS G+PGP G  
Sbjct: 508 DPGTVGPPG--------------------PV-----GERGAPGNRGFPGSDGLPGPKGAQ 542

Query: 837 GPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPP 895
           G  GP G  G  G  G PG  G PG PG RGL G PG  G +G  G  G PGE G PGPP
Sbjct: 543 GERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP 602

Query: 896 GP---EGPPGI----SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
           G     G PG       +G  GDPG PG+ G+ G PG +G PG  G   PS
Sbjct: 603 GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPS 653



 Score =  317 bits (813), Expect = 3e-86
 Identities = 191/460 (41%), Positives = 223/460 (48%), Gaps = 73/460 (15%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
            P G PG  GP G+ G PG  G  G PG  G PG +G  G  G  G  G QG  G PG KG
Sbjct: 802  PLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861

Query: 507  EPGRDGDKGDRGLPGFPGL---------HGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKG 557
            EPG  G KGD G PG  GL         +G+PG KG  G +G  G+ GF G  G  G  G
Sbjct: 862  EPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921

Query: 558  NAGFPGLPGPAGEPGRHGKDGLMGSPGF------KGEAGSPGAPGQDGTRGE---PGIPG 608
             AG PG  GP GEPG+ G  GL G PG       +G AG PG PG  G  GE   PG  G
Sbjct: 922  PAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDG 981

Query: 609  FPGNRGLMGQKGEIGPPGQQGKKGAPGMP------------GLMGSNGSPGQPGTPGSKG 656
             PG  G  GQ+G +G PGQ+G++G PG+P            G  G  G PG  G PGS G
Sbjct: 982  PPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG 1041

Query: 657  SKGEPGIQ------GMPGASGLKGEPGATGSPGE---PGYMGLPGIQGKKGDKGNQGEKG 707
              GEPG +      G PG  G  GE G  G PG    PG  G PG  G  G  G+ G++G
Sbjct: 1042 PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRG 1101

Query: 708  IQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKG 767
              G +G  G  G  G++G+ G  G +G++G+ G+ G RG  G +G +G+ GL GP GP G
Sbjct: 1102 DPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNG 1161

Query: 768  QPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSP 827
            + G  G  GP G  G PG                    PV                 G  
Sbjct: 1162 EQGSAGIPGPFGPRGPPG--------------------PV--------------GPSGKE 1187

Query: 828  GIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRG 867
            G PGP GPIGP G RG  G  G +G PG  G PG PG  G
Sbjct: 1188 GNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  305 bits (782), Expect = 1e-82
 Identities = 194/484 (40%), Positives = 220/484 (45%), Gaps = 65/484 (13%)

Query: 490 PGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGK 549
           PG       RG  G KGEPG        G+ G PG  G PGS+G  G +G KG PG  G 
Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVV--TGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGP 157

Query: 550 KGAKGEKGNAGFPGLPGPAGEPGRHGKDGLM------------------------GSPGF 585
           +G  GE G  G PG PGP G P   G DGL                         GS G 
Sbjct: 158 QGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGP 217

Query: 586 KGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGS 645
            G  G  G  GQ G  G  G PG PG+ G MG  G  GP G  GK G  G PG  G+ G 
Sbjct: 218 VGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGE 277

Query: 646 PGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGE 705
            G  G+PG++G  G PG+ G+ G  G KG  G  G  G PG  G  G  G  G  G  G 
Sbjct: 278 VGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGP 337

Query: 706 KGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGS---KGESGVDGLMGP 762
           +G+ G++G  G QG PGQ+G  G  G  G  G  G PG  G  G+   KGE+G  G  GP
Sbjct: 338 RGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397

Query: 763 AGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLS 822
            GP+GQ G+ GP GP G  G PG                                D    
Sbjct: 398 EGPQGQRGETGPPGPVGSPGLPG----------------------------AIGTDGTPG 429

Query: 823 QHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG 882
             G  G PG  GP G  GP G PG  G  G  G+ G PG PGV G KG  G  GE G  G
Sbjct: 430 AKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHG 489

Query: 883 ----FGYPGEQ---GPPGPPGPEGPPG-ISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                G PGE+   GP G PG  GPPG + + G PG+ G PG DG  G  G QG+ GP G
Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVG 549

Query: 935 ICDP 938
              P
Sbjct: 550 SSGP 553



 Score =  303 bits (777), Expect = 4e-82
 Identities = 176/423 (41%), Positives = 218/423 (51%), Gaps = 34/423 (8%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PG  GE  NGP+             G  G QGP G PG+ G PG PGQ G  G PG QG+
Sbjct: 833  PGSRGE--NGPTGA----------VGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGL 880

Query: 484  AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
            AG+PG  G  G+ G +G  G +G PG  G  G  G  G PG  G PG  G +G  G +G 
Sbjct: 881  AGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGP 940

Query: 544  PGFYGKKGAK---GEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600
            PG  G  G+    G++G AG PG PG  G+PG  G+ G  G PG  G  G  G  G  G 
Sbjct: 941  PGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQ 1000

Query: 601  RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660
            RGE G+PG PG     G  G++GP G  G KG PG  G  GSNG  G+PG  G  G+ G 
Sbjct: 1001 RGERGMPGLPGP---AGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGT 1057

Query: 661  PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQ---GQKGENGR 717
            PG  G  G  G +G+PG  G PG  G  G PG  G  GD G +G+ G +   G  G  G+
Sbjct: 1058 PGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGK 1117

Query: 718  QGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGP 777
            +G+PG QG +G  G  G+RG++G+ G RG  G +G  G  G  G  G  G PG  GP+GP
Sbjct: 1118 RGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGP 1177

Query: 778  PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIG 837
            PG  G  G+E +   +  +    +R  +    ++G            G PG PGPPGP G
Sbjct: 1178 PGPVGPSGKEGNPGPLGPIGPPGVRGSVG---EAG----------PEGPPGEPGPPGPPG 1224

Query: 838  PEG 840
            P G
Sbjct: 1225 PPG 1227



 Score =  191 bits (485), Expect = 3e-48
 Identities = 133/374 (35%), Positives = 165/374 (44%), Gaps = 79/374 (21%)

Query: 596 GQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSK 655
           G+ G +GEPG+   P   G+ G+ G  GPPG QG +G           G  G+PG  G +
Sbjct: 110 GRKGQKGEPGL--VPVVTGIRGRPGPAGPPGSQGPRG---------ERGPKGRPGPRGPQ 158

Query: 656 GSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQ--------------------- 694
           G  GEPG         + G+PGA G PG P + G  G+                      
Sbjct: 159 GIDGEPG---------VPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVG 209

Query: 695 ---GKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSK 751
              G  G  G +G +G+QGQ+G  G  G PG+ G  G  G  G RG +G PG  G  G  
Sbjct: 210 LMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEP 269

Query: 752 GESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQS 811
           G +G  G +G AG  G  G PG  G PGL G  G +  E    +V               
Sbjct: 270 GRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAP------------ 317

Query: 812 GRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGR---DGVPG---LVGVPGRPGV 865
                        G  G  GP G +GP GPRG+PG  GR    G PG     G+PG+PG 
Sbjct: 318 ----------GSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGP 367

Query: 866 RGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPG 925
            G  G+PG +G  G+ G    GE GP G  GPEGP     +G  G+ G PG  G  G PG
Sbjct: 368 MGPLGIPGSSGFPGNPGM--KGEAGPTGARGPEGP-----QGQRGETGPPGPVGSPGLPG 420

Query: 926 IQGQPGPPGICDPS 939
             G  G PG   P+
Sbjct: 421 AIGTDGTPGAKGPT 434



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 50/115 (43%), Positives = 60/115 (52%), Gaps = 20/115 (17%)

Query: 832 PPG---PIGPEGPRGLP-----GLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF 883
           PPG   P+  + P G       G  G+ G PGLV     P V G++G PG  G  GSQG 
Sbjct: 88  PPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLV-----PVVTGIRGRPGPAGPPGSQG- 141

Query: 884 GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
              GE+GP G PGP GP GI      G+PG+PG+ G  G PG    PGP G+  P
Sbjct: 142 -PRGERGPKGRPGPRGPQGID-----GEPGVPGQPGAPGPPGHPSHPGPDGLSRP 190


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  384 bits (987), Expect = e-106
 Identities = 236/559 (42%), Positives = 271/559 (48%), Gaps = 85/559 (15%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG--------------- 491
            P G  G  GPKG PG PG  G PG PGQ G+ G+QG  G PG PG               
Sbjct: 953  PQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMG 1012

Query: 492  ------SPGIQGARGLPGYKGEPGRDGDKGDRGLPG---------FPGLHGMPGSKGEMG 536
                   PG  G +GLPG  G+ G  GD G  GLPG         FPG  G+PG  G +G
Sbjct: 1013 ERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALG 1072

Query: 537  AKGDKGSPGFYGKKGAKGEKGNAG------FPGLPGPAGEPGRHG--------------- 575
             KG++G PG  G  G+ GE+G AG       PG PGP G PG  G               
Sbjct: 1073 LKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1132

Query: 576  KDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPG 635
            +DGL G  G  G AG  G PG+DG +GE G PG  G++G    KGE GPPG  G +G  G
Sbjct: 1133 RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKG---DKGEQGPPGPTGPQGPIG 1189

Query: 636  MPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA------SGLKGEPGATGSPGEPGYMG 689
             PG  G++G PG  G  G  G KG+ G +G PG        GL G PG  G  G+ G MG
Sbjct: 1190 QPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMG 1249

Query: 690  LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIG 749
             PG  G +G  G  G  G QG  G  G  G  G++G  G  G  G  GE G PG +G  G
Sbjct: 1250 PPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERG 1309

Query: 750  SKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLL 809
             KGESG  G  GP GPKG PGD GP+G PG  G PG             D          
Sbjct: 1310 EKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGD----- 1364

Query: 810  QSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDG---------VPGLVGVP 860
                 +  D    Q GSPG  G PGP GP G RG PG  G +G           GL G P
Sbjct: 1365 -----KGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPP 1419

Query: 861  GRPGVRGLKGLPGRNGEKGSQGFGYP-GEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDG 919
            G+ G  G +G PG+ G  G +G   P GEQG PG PGP+GPPG     P G PGLPG  G
Sbjct: 1420 GKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPG-----PMGPPGLPGLKG 1474

Query: 920  DHGKPGIQGQPGPPGICDP 938
            D G  G +G PG  G+  P
Sbjct: 1475 DSGPKGEKGHPGLIGLIGP 1493



 Score =  383 bits (983), Expect = e-106
 Identities = 238/586 (40%), Positives = 289/586 (49%), Gaps = 80/586 (13%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PG  G+  N  +     P   I PPG+ G  G  G PG+PG  G PG PG++G PG +G 
Sbjct: 717  PGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGG 776

Query: 484  AGTPGVPGS---PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540
             G PG  G    PG +G +G  G +G  G  G+KG+ G PGF G  G+ G +GE+G  G 
Sbjct: 777  QGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGP 836

Query: 541  KGSPGFYGKK------------GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGE 588
            +G  G  G K            G  GEKG  G PGLPG  G  G  G  G  G PG  GE
Sbjct: 837  RGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGE 896

Query: 589  AGSPGAPGQDGTRGE------------PGIPGFPGNRGLMGQKGEIGPPGQQ---GKKGA 633
             G  G PG+ G RG+             GI G PG +G  G  G  GPPG++   G +G 
Sbjct: 897  KGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGP 956

Query: 634  PGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGM---PGASGLKGEPGATGS--------- 681
             G PG  G  G PG+ G PG  G +GE G QG    PG  G+ G  G TG          
Sbjct: 957  TGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGH 1016

Query: 682  ---PGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGE 738
               PG PG  GLPG+ GK+G KG+ G  G+ G+ G  G +G PG +G+ G  GA G +G 
Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGN 1076

Query: 739  KGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCT 798
            +G PG  G  GS GE G     G AGP G PG PGPQGPPG  G+ G    +        
Sbjct: 1077 EGPPGPPGPAGSPGERGP---AGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133

Query: 799  DVIRAQLPVLLQSGRI--RNCDHCLSQHGSP---------GIPGPPGPIGPEGPRGLPGL 847
            D ++  + +   +G +     D    + G P         G  GPPGP GP+GP G PG 
Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193

Query: 848  PGRDGVP---------------GLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPP 892
             G DG P               G  G PG PG  GL+GLPG  GEKG    G  G+ GPP
Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGET--GDVGQMGPP 1251

Query: 893  GPPGPEGPPGI----SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            GPPGP GP G       +GPPG  G PG  G+ G+PG  G+PG PG
Sbjct: 1252 GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPG 1297



 Score =  382 bits (982), Expect = e-106
 Identities = 230/525 (43%), Positives = 266/525 (50%), Gaps = 51/525 (9%)

Query: 448  PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPG---VPGSPGIQGARGLPGY 504
            PG  GL GP G  GL GN G PG PG  G PG +G AG  G   +PG PG QG  G  G 
Sbjct: 1059 PGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGE 1118

Query: 505  KGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKG---DKGSPGFYGKKGAKGEKGNAGF 561
            KG PG  G +G  G  G  G  G+PG  G +G  G   DKG  G  G+KG+KG+KG  G 
Sbjct: 1119 KGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGP 1178

Query: 562  PGLPGPA------------GEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGF 609
            PG  GP             GEPG  G+ GL G  G +G  G PG PG  G +G PG PG 
Sbjct: 1179 PGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238

Query: 610  PGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA 669
             G  G +GQ G  GPPG +G  GAPG  G  G  G  G PG  G KG  GE G  G+PG 
Sbjct: 1239 KGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298

Query: 670  SGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGH 729
             G  G  G  G  GE G  G  G  G KG  G+ G KG  G  G  G  G PG+ G  G 
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ 1358

Query: 730  HGAKGERGEKGEPGVRGAIGSKGESGVD------GLMGPAGPKGQPGDPGPQGPPGLDGK 783
             G  G++G+ GEPG  G+ G  GE G        G  GPAGP+G+ G+ G +G  GL+G 
Sbjct: 1359 DGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGP 1418

Query: 784  PGREFSEQFIRQVCTDVIRAQ-LPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPR 842
            PG+           T  I  Q  P       +R     + + G PG PGP GP GP GP 
Sbjct: 1419 PGK-----------TGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPP 1467

Query: 843  GLPGL---------PGRDGVPGLVGVPGRPGVRGLKGLP---GRNGEKGSQGF-GYPGEQ 889
            GLPGL          G  G+ GL+G PG  G +G +GLP   G +G KG QG  G  G  
Sbjct: 1468 GLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPI 1527

Query: 890  GPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            GPPGPPG  GPPG   +G  G  G  G  G+ G PG  G PGPPG
Sbjct: 1528 GPPGPPGLPGPPG--PKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  381 bits (979), Expect = e-105
 Identities = 250/590 (42%), Positives = 289/590 (48%), Gaps = 93/590 (15%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PGF G+ +    D G    P   P G+ G +GPKG  G  G+PG  G PG+ GK      
Sbjct: 816  PGFKGD-MGIKGDRGEIGPPG--PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGK------ 866

Query: 484  AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
             G PG+PG PG QG +G  G+ G PG +G+KG RG PG PG  G  G  G  G +G +G 
Sbjct: 867  LGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGI 926

Query: 544  PGFYGKKGAKGEKGNAGFPG------------LPGPAGEPGRHGKDGLMGSPG------F 585
             G  G KG  G  G AG PG             PGP G PG  GKDGL G PG      F
Sbjct: 927  TGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986

Query: 586  KGEAGSPGAPG------------QDGTRGEPGIPGFPGNRGLMG------QKGEIGPPGQ 627
            +G+ G PG PG              G RG PG PG PG +GL G       KG+ GP G 
Sbjct: 987  QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGL 1046

Query: 628  QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGY 687
             GK G PG+ G  G  G PG  G  G KG++G PG  G  G+ G +G  GA G  G PG 
Sbjct: 1047 PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGR 1106

Query: 688  MGLPGIQGKKGDKGNQGEKGIQGQKGENGRQG---IPGQQGIQGHHGAKGERGEKGEPGV 744
             G  G  G  G+KG  GEKG QG  G +G QG   +PG  G  G  G  G++GE GEPG 
Sbjct: 1107 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQ 1166

Query: 745  RGAIGSKGESGVDGLMGPAGPKGQPG------DPGPQGPPGLDGKPGREFSEQFIRQVCT 798
            +G+ G KGE G  G  GP GP GQPG      +PGP+G  GL G+ G E    F      
Sbjct: 1167 KGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG- 1225

Query: 799  DVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGL------PGRDG 852
                   PV LQ   +        + G  G  GPPGP GP GP G PG       PG  G
Sbjct: 1226 -------PVGLQG--LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIG 1276

Query: 853  VPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGEQGPPG---PPGPEGPPGIS---- 904
             PG VG  G PG  G  GLPG  G  G +G  G  GE GP G   PPGP+GPPG      
Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336

Query: 905  ---------KEGPPGDPGLPGKDG------DHGKPGIQGQPGPPGICDPS 939
                       GPPG+PG  G+DG      D G+PG  G PGP G   PS
Sbjct: 1337 SPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPS 1386



 Score =  380 bits (975), Expect = e-105
 Identities = 221/515 (42%), Positives = 261/515 (50%), Gaps = 30/515 (5%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
            P G  GL G  G  G PG+ G  G+PG  G  G +G+ G PG  G PG +G  G  G +G
Sbjct: 560  PAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARG 619

Query: 507  EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
             PG+ G KGDRG  G  GL G  G +G+ G  G  G PG  G++G  GE G  G PG PG
Sbjct: 620  MPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPG 679

Query: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIP---GFPGNRGLMGQKGEIG 623
            P G  G  G  G  G PG  G  G PG  G  G +GEPG P   G PG +GL G +G IG
Sbjct: 680  PRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIG 739

Query: 624  PPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPG 683
            PPG++G  G PG+PG+ G++G PG    PG +G  GE G QG PG  G  G PG  G  G
Sbjct: 740  PPGEKGPLGKPGLPGMPGADGPPGH---PGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKG 796

Query: 684  EPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPG 743
              G  GL G +G+KG+ G  G KG  G KG+ G  G PG +G  G  G KG  G  G+PG
Sbjct: 797  ADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPG 856

Query: 744  VRGAIGSKGESGVDGL------MGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVC 797
              G  G KG+ GV GL       GP G  G PG PG  G  G  G PG+           
Sbjct: 857  PLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTG 916

Query: 798  TDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLV 857
                R    +  + G   N        G  G PG  GP GP+GP G PG  G  G PG  
Sbjct: 917  PRGERGPRGITGKPGPKGNS----GGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKD 972

Query: 858  GVPGRPGVRGLKGLPGRNGEKGSQG-------------FGYPGEQGPPGPPGPEGPPGIS 904
            G+PG PG RG  G  G+ G  G  G              G  G  GPPGPPG +G PG++
Sbjct: 973  GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLA 1032

Query: 905  -KEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
             KEG  GDPG  G  G  G PG++G PG  G+  P
Sbjct: 1033 GKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1067



 Score =  378 bits (971), Expect = e-104
 Identities = 234/562 (41%), Positives = 277/562 (49%), Gaps = 70/562 (12%)

Query: 425  GFNGECLNGPSDVGST-PAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            G  GE    P DVG   P     PPG  G  G +G  G  G  G PGQ G  G  G+ G+
Sbjct: 580  GLKGE----PGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGL 635

Query: 484  AGTPGVPG---SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540
            AG PG  G    PG  G  G PG  GE G DG+ G RGLPG PG  G+ G KG  G  G 
Sbjct: 636  AGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGP 695

Query: 541  KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHG---KDGLMGSPGFKGEAGSPGAPGQ 597
             G  G  G+ G KG  G  G PG PG  G PG  G     G +G PG KG  G PG PG 
Sbjct: 696  PGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGM 755

Query: 598  DGTRGEPGIPGFPG------NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGT 651
             G  G PG PG  G       +G  G +G IG PG +G KGA G+ GL G+ G  G+ G 
Sbjct: 756  PGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF 815

Query: 652  PGSKGS---------------KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQG- 695
            PG KG                +GE G +G  G  G  G+PG  G PGE G +G+PG+ G 
Sbjct: 816  PGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGY 875

Query: 696  --KKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGE 753
              ++G KG+ G  G  G  GE G +G PG+ G +G  G  G RGE+G  G+ G  G KG 
Sbjct: 876  PGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGN 935

Query: 754  SGVDGLMGPAG------PKGQPGDPGPQGPP------GLDGKPGREFSEQFIRQV----C 797
            SG DG  GP G      P+G  G PGP+GPP      GL G PG+     F  +      
Sbjct: 936  SGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 995

Query: 798  TDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGV---P 854
              V+  Q P                + G  G  G PGP GP G +GLPGL G++G    P
Sbjct: 996  PGVVGPQGPT--------------GETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDP 1041

Query: 855  GLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPG-ISKEGPPGDP 912
            G  G+PG+ G  GL+G PG  G  G  G  G  G +GPPGPPGP G PG     G  G  
Sbjct: 1042 GPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPI 1101

Query: 913  GLPGKDGDHGKPGIQGQPGPPG 934
            G+PG+ G  G PG  G+ G PG
Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPG 1123



 Score =  374 bits (961), Expect = e-103
 Identities = 240/592 (40%), Positives = 274/592 (46%), Gaps = 118/592 (19%)

Query: 418  ETACEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK 477
            E A   PG   E   GP      P P    PG  G  G  GDPG  G PG PG PG DG 
Sbjct: 457  EPAIIEPGMLIEGPPGPEGPAGLPGP----PGTMGPTGQVGDPGERGPPGRPGLPGADGL 512

Query: 478  PG------------------------------------------YQGIAGTPGVPGSPGI 495
            PG                                           +G AG  G+ G PG 
Sbjct: 513  PGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGP 572

Query: 496  QGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGE 555
             G  G  G KGEPG  G +G RG+ G PG  G PG +G  G+ G +G PG  G KG +G 
Sbjct: 573  VGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGF 632

Query: 556  KGNAGFPGL------PGPAGEPGRHGKDG------------LMGSPGFKGEAGSPGAPGQ 597
             G AG PG       PGP+G PG  G DG            L G PG +G  G  G PG 
Sbjct: 633  DGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGP 692

Query: 598  DGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGS 657
             G  G  G+ G PG +G +G +GE GPPGQQG  GA G+PG  G+ G PG+      KG 
Sbjct: 693  PGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGE------KGP 746

Query: 658  KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQ------GKKGDKGNQGEKGIQGQ 711
             G+PG+ GMPGA G  G PG  G PGE G  G PG Q      G +G KG  G +G++G 
Sbjct: 747  LGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGT 806

Query: 712  KGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGD 771
            KGE G  G P   G +G  G KG+RGE G PG RG  G +G  G  G  G  GP G PG+
Sbjct: 807  KGEKGEDGFP---GFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGE 863

Query: 772  PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPG 831
             G  G PGL G PGR+                                     GS G PG
Sbjct: 864  KGKLGVPGLPGYPGRQ----------------------------------GPKGSIGFPG 889

Query: 832  PPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQG 890
             PG  G +G RG PG PG  G  G  G  G  G RG+ G PG  G  G  G  G PGE+G
Sbjct: 890  FPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERG 949

Query: 891  PPGPPGPEGPPG-ISKEGPPGDPGLPGKDGDHGKPGIQGQ---PGPPGICDP 938
            P GP GP G PG     GPPG  GLPG  G  G+ G QG+   PGPPG+  P
Sbjct: 950  PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP 1001



 Score =  360 bits (924), Expect = 3e-99
 Identities = 232/584 (39%), Positives = 275/584 (47%), Gaps = 93/584 (15%)

Query: 431  LNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPG------------NPGYPGQPGQDGKP 478
            L  P + G    P +  PG PG QGPKG  G PG             PG PG  GQ G  
Sbjct: 858  LGPPGEKGKLGVPGL--PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPT 915

Query: 479  GYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPG------------LH 526
            G +G  G  G+ G PG +G  G  G  G PG  G  G +G  GFPG            L 
Sbjct: 916  GPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLP 975

Query: 527  GMPGSKGEMGAKGDKGSPG---FYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSP 583
            G PG +GE G +G  G PG     G +G  GE G  G  G PGP G PG  G  GL G  
Sbjct: 976  GHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE 1035

Query: 584  GFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGL------MGQKGEIGPPGQQGKKGAPG-- 635
            G KG+ G  G PG+DG    PG+ GFPG+RGL      +G KG  GPPG  G  G+PG  
Sbjct: 1036 GTKGDPGPAGLPGKDGP---PGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGER 1092

Query: 636  -------------MPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682
                          PG  G  G  G+ G PG KG +G  G  G+ G  GL G  G  G P
Sbjct: 1093 GPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPP 1152

Query: 683  GEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERG---EK 739
            GE G  G  G  G+KG KG++GE+G  G  G  G  G PG  G  G  G +G++G   +K
Sbjct: 1153 GEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQK 1212

Query: 740  GEPGVRGAIGSKGESGVDGLMGPAGPKGQPGD------PGPQGPPGLDGKPGREFSEQFI 793
            G+ G RG  G  G  G+ GL GP G KG+ GD      PGP GP G  G PG +  +   
Sbjct: 1213 GDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPP 1272

Query: 794  RQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGP---------------IGP 838
              +       +     ++G          + G PG  GPPGP                GP
Sbjct: 1273 GGIGNPGAVGEKGEPGEAG----------EPGLPGEGGPPGPKGERGEKGESGPSGAAGP 1322

Query: 839  EGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGP--- 894
             GP+G PG  G  G PG VG PG PG  G  G  G++G  G +G  G PG+ G PGP   
Sbjct: 1323 PGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE 1382

Query: 895  PGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            PGP GPPG  K GPPG  G  G+ G+ G  G  G  GPPG   P
Sbjct: 1383 PGPSGPPG--KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGP 1424



 Score =  302 bits (774), Expect = 9e-82
 Identities = 182/432 (42%), Positives = 208/432 (48%), Gaps = 52/432 (12%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
            PPG  G QGP G PG  G  G PG  GQ G  G +G  G  G PG PG  G +GLPG  G
Sbjct: 1178 PPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPG 1237

Query: 507  EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566
            E G  GD G  G PG PG  G  G+ G  G +G  G  G  G  G KGE G AG PGLPG
Sbjct: 1238 EKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPG 1297

Query: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGA---PGQDGTRGEPGIPGFPGNRGLMGQKG--- 620
              G PG  G+ G  G  G  G AG PG    PG DG +G PG  GFPG+ G  G+ G   
Sbjct: 1298 EGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAG 1357

Query: 621  EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATG 680
            + GPPG +G  G PG  G  G  G PG  G PG +G  G  G +G  G  G KGE G  G
Sbjct: 1358 QDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEG 1417

Query: 681  SPGEPGYMGLPGIQGKKGDKGNQG------EKGIQGQKGENGRQGIPGQQGIQGHHGAKG 734
             PG+ G +G  G  GK G  G +G      E+G+ G  G +G  G  G  G+ G  G  G
Sbjct: 1418 PPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSG 1477

Query: 735  ERGEKGEPGVRGAIG------SKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREF 788
             +GEKG PG+ G IG       KG+ G+ G  G +GPKG+ G  GP GP G  G PG   
Sbjct: 1478 PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG--- 1534

Query: 789  SEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLP 848
                            LP                  G  G  G  GP GP+G  G PG P
Sbjct: 1535 ----------------LP---------------GPPGPKGAKGSSGPTGPKGEAGHPGPP 1563

Query: 849  GRDGVPGLVGVP 860
            G  G PG V  P
Sbjct: 1564 GPPGPPGEVIQP 1575



 Score =  285 bits (728), Expect = 2e-76
 Identities = 206/555 (37%), Positives = 249/555 (44%), Gaps = 91/555 (16%)

Query: 424 PGFNGECLNGPSDVG--STPAPCICPPGKPG--LQGPKGDPGLPGNPGYPGQPGQDGKPG 479
           PG   E     +D    S PAP   PPG+    L+G   +  +         P  D    
Sbjct: 370 PGAGAEIPTSTADTSNSSNPAP---PPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSS 426

Query: 480 YQGIAGTPGVPGSP-----GIQGARGLPGYKGEPGR-DGDKGDRGLPGFPGLHGMPGSKG 533
              I   PG+P +      GI G RG  G KGEP   +      G PG  G  G+PG  G
Sbjct: 427 PSEIG--PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPG 484

Query: 534 EMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGE----PGRHGKDGLMGSPG----- 584
            MG  G  G PG   ++G  G  G  G  GLPGP G     P R G  G  GS G     
Sbjct: 485 TMGPTGQVGDPG---ERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSA 541

Query: 585 ---------------FKGEAGSPGAPGQDGTRGEPG---IPGFPGNRGLMGQKGEIGPPG 626
                           +G AG  G  G+ G  G PG   + G PG+ G  G +G  GPPG
Sbjct: 542 QESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPG 601

Query: 627 QQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPG 686
             GK   PG  G  GS+G+ G PG  G KG +G  G+ G+PG  G +G+PG +G PG PG
Sbjct: 602 PAGK---PGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658

Query: 687 YMGLPGIQGKKGDKGNQGE---KGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPG 743
             G  G  G+ G +G  GE   +G+ G KG  G  G PG  G+ G  G KG  G +GEPG
Sbjct: 659 DDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPG 718

Query: 744 VRGAIGSKGESGV---DGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDV 800
             G  G+ G  G+    G +GP G KG  G PG  G PG DG PG    E          
Sbjct: 719 PPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE---------- 768

Query: 801 IRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVP 860
                                   G PG  G  GP GP+GP G PG  G  G  G+ G+ 
Sbjct: 769 ------------------------GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLK 804

Query: 861 GRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPG-ISKEGPPGDPGLPGKDG 919
           G  G +G  G PG  G+ G +  G  GE GPPGP G +GP G   + GP GDPG  G  G
Sbjct: 805 GTKGEKGEDGFPGFKGDMGIK--GDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPG 862

Query: 920 DHGKPGIQGQPGPPG 934
           + GK G+ G PG PG
Sbjct: 863 EKGKLGVPGLPGYPG 877



 Score =  209 bits (532), Expect = 1e-53
 Identities = 134/316 (42%), Positives = 157/316 (49%), Gaps = 23/316 (7%)

Query: 425  GFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPG---LPGNPGYPGQPG---QDGKP 478
            G  GE  +GPS     P P     G PG  GPKG PG    PG+PG PG+PG   QDG P
Sbjct: 1309 GEKGE--SGPSGAAGPPGP----KGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPP 1362

Query: 479  GYQGIAGTPGVPGSPGIQGA---RGLPGYKGEPGR---DGDKGDRGLPGFPGLHGMPGSK 532
            G +G  G PG  GSPG  G     G PG +G PG    +G +G++G  G  GL G PG  
Sbjct: 1363 GDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKT 1422

Query: 533  GEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSP 592
            G +G +G  G PG  G +G  G  G  G PG PGP G PG  G  GL G  G  G  G  
Sbjct: 1423 GPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEK 1482

Query: 593  GAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTP 652
            G PG  G  G PG  G  G+RGL G +G  GP G+Q   G  G  G +G  G PG PG P
Sbjct: 1483 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ---GITGPSGPIGPPGPPGLPGPP 1539

Query: 653  GSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQK 712
            G KG+KG  G  G  G +G  G PG  G PGE     LP IQ  +  +     + +    
Sbjct: 1540 GPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV-IQPLP-IQASRTRRNIDASQLLDDGN 1597

Query: 713  GENGRQGIPGQQGIQG 728
            GEN      G + I G
Sbjct: 1598 GENYVDYADGMEEIFG 1613



 Score =  164 bits (414), Expect = 5e-40
 Identities = 111/286 (38%), Positives = 138/286 (48%), Gaps = 49/286 (17%)

Query: 679 TGSPGEPGYMGLP--------GIQGKKGDKGNQGEKGI-------QGQKGENGRQGIPGQ 723
           T SP E G  G+P        GI G +G+KG +GE  I       +G  G  G  G+PG 
Sbjct: 424 TSSPSEIG-PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP 482

Query: 724 QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPK-------GQPGDPGPQG 776
            G  G  G  G+ GE+G PG        G  G DGL GP G         G  GD G +G
Sbjct: 483 PGTMGPTGQVGDPGERGPPG------RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKG 536

Query: 777 PPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI 836
           P        +E   Q I Q     +R     +  +GR       +   GS G+ G PG +
Sbjct: 537 PM----VSAQESQAQAILQQARLALRGPAGPMGLTGR----PGPVGPPGSGGLKGEPGDV 588

Query: 837 GPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPP 892
           GP+GPRG+ G PG  G PG     GR G  G +G+PG+ G KG +GF    G PGE+G  
Sbjct: 589 GPQGPRGVQGPPGPAGKPGR---RGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHR 645

Query: 893 GPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
           G PGP GPP     GPPGD G  G DG+ G  G+ G+PGP G+  P
Sbjct: 646 GDPGPSGPP-----GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGP 686


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  381 bits (978), Expect = e-105
 Identities = 241/582 (41%), Positives = 299/582 (51%), Gaps = 91/582 (15%)

Query: 428  GECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGN---PGYPGQPGQDGKPGYQGIA 484
            G  L GP+     P P    PG  GL GP+G PGLPG     G PG PG+DG  G  G  
Sbjct: 2216 GRGLTGPTGAVGLPGP----PGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDR 2271

Query: 485  GTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDR--GLPGFPGLHGMPGSK-----GEMGA 537
            G+PGVPGSPG+ G     G KGEPG  G  G    GLPG  G  G PG       GE GA
Sbjct: 2272 GSPGVPGSPGLPGP---VGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGA 2328

Query: 538  KGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ 597
            KGD+G PG    +G KGE G AG PG PG  G+ G  G  G  G PG  G  GSPG PG 
Sbjct: 2329 KGDRGLPG---PRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GVPGSPGPPGP 2384

Query: 598  DGTRGEPGIPGFPGNRGLMG------QKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGT 651
             G +G+ G+PG PG  G++G       +GE+G PG  G++G  G PG  G  G  G PG 
Sbjct: 2385 PGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGP 2444

Query: 652  PGS---------KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGY------MGLPGIQGK 696
            PGS         KG KG+PG+ G+PG  G +GEPG  G  G PG        G PG +G+
Sbjct: 2445 PGSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGE 2503

Query: 697  KGDKGNQGEKGIQGQKGEN----------GRQGIPGQQGIQGHHGAKGERGEKGEPGVRG 746
            +G+KG+ G  G++G KG++          G +G  G++G +G  G KG RG+ G+PG +G
Sbjct: 2504 RGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563

Query: 747  AIGS---KGESGVDGLMGPAGPKGQPGD---PGPQGPPGLDGKPGREFSEQFIRQVCTDV 800
            + G    KG +G+ GL G  GP+GQPG    PG  G PG DG PG    +  +  +    
Sbjct: 2564 SKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623

Query: 801  IRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVP 860
            ++ +  V    G     D      G  G PG PG  G +G  G PG+PG+ G PG  G+ 
Sbjct: 2624 LKGERGVKGACG----LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLI 2679

Query: 861  GRPGVRGLKGLPGRNGEKGSQGF-------GYPGEQG------PPGPPG------PEG-- 899
            G  G RG  G PG  G++G +G        G+PG  G      PPGPPG      PEG  
Sbjct: 2680 GPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQ 2739

Query: 900  -------PPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                   PPG    G PG PG PG+ G+ G+PG  G  G  G
Sbjct: 2740 GQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781



 Score =  373 bits (957), Expect = e-103
 Identities = 232/564 (41%), Positives = 269/564 (47%), Gaps = 108/564 (19%)

Query: 441  PAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARG 500
            P P  CP G+ G  G  G  G  G PG PG PG+ G PG QG       PGS   +G RG
Sbjct: 1246 PCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQG------PPGSATAKGERG 1299

Query: 501  LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAG 560
             PG  G PG  G  G+ G PG PGL G PG  G  G  G++G  G  G+ GA G+     
Sbjct: 1300 FPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGE 1359

Query: 561  FPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP-----GQDGTRGE------------ 603
             PGLPG  G+PG  G  G  G  G  G  G PG P     G  G RGE            
Sbjct: 1360 GPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIA 1419

Query: 604  PGIPGFPGNRGLMGQKGEIGPPGQQGKKG--APGMPGLMGSNGSPGQPGTPGSKGSKGEP 661
            PG PG PG  G  G +G +GPPG++G+KG    G PGL G  GSPG+ G  G  G+ G  
Sbjct: 1420 PGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPK 1479

Query: 662  GIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIP 721
            G +G PG  G  GE G  G PG  G  GLPG+ G+ G KG +G  G  G++GE G  G P
Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRP 1539

Query: 722  GQQGIQGH--HGAKGERGEKGEPGVRGAIGSKGESGVDGLM--GPAGPKGQPGDPGP--- 774
            G   + G    G KGE+G+ G  G RGA G +GE G  GL+  G  GPKG PGD GP   
Sbjct: 1540 GDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGL 1599

Query: 775  ---QGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPG 831
                GPPG  G PG                                     + G PG PG
Sbjct: 1600 TGRAGPPGDSGPPG-------------------------------------EKGDPGRPG 1622

Query: 832  PPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRN---GEKGSQG------ 882
            PPGP+GP G  G  G  G +G PG  G+PG+ G RGL+G PG     GEKG QG      
Sbjct: 1623 PPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDG 1682

Query: 883  -FGYPGEQGPP---GPPGPEGPPG--------------------ISKEGPPGDPGLPGKD 918
              G PG  GP    G PGP GPPG                        GP GDPGLPG  
Sbjct: 1683 RNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAP 1742

Query: 919  GDHGKPGIQGQPGP---PGICDPS 939
            G+ G  G +G PGP   PG+  P+
Sbjct: 1743 GERGIEGFRGPPGPQGDPGVRGPA 1766



 Score =  371 bits (953), Expect = e-102
 Identities = 235/582 (40%), Positives = 284/582 (48%), Gaps = 96/582 (16%)

Query: 447  PPGK--PGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGY 504
            PPG   PG  GPKGDPG  G  G  G+ G  G  G  G  G PG PG PG  G RG  G 
Sbjct: 1576 PPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGE 1635

Query: 505  KGEPGRDGDKGDRGLPGFPG---LHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGF 561
             GE G +G  GD GLPG  G   L G PG +G +G KGD+G PG  G+ G+ G  G  G 
Sbjct: 1636 VGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGD 1695

Query: 562  PGLPGPAGEPGR-------------HGKDGLMGSPGFKGEAGSPGAPGQ---DGTRGEPG 605
             G PGP G PGR              G  G  G  G KG+ G PGAPG+   +G RG PG
Sbjct: 1696 RGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPG 1755

Query: 606  IPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQG 665
              G PG RG  G+KG+ GPPG  G+ G  G PG  G +G  G  G  G  G  G PG++G
Sbjct: 1756 PQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRG 1815

Query: 666  MPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQG 725
              G  G  G PG    PG+PG  G PG+ GK G+ G+ GE G +G+KG++G  G  G+ G
Sbjct: 1816 EQGLPGPSGPPGL---PGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDG 1872

Query: 726  IQGHHGAKGERGEKGEPGVRGAIGSKGES--GVDGLMGPAGPKGQPGDPGPQGPP---GL 780
             +G  GA G  G +G PG+ G +G  G+   GV G  GP G +G+ G  G QG P   GL
Sbjct: 1873 PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGL 1932

Query: 781  DGKPG-----------REFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGI 829
             G+PG                  +R++      +    L    R R       + G PG 
Sbjct: 1933 RGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGK 1992

Query: 830  PGP---------------PGP----------IGPEGPRGLPGLPGRDGVPGL------VG 858
             GP               PGP           GP GP GL G PG+ G+PGL      VG
Sbjct: 1993 EGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVG 2052

Query: 859  VPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGP--------------EGPPGI 903
              GRPG RG +G  G  GE+G  G  G PG  GPPGPPGP              +GPPG+
Sbjct: 2053 EAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL 2112

Query: 904  ----------SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935
                        +GP GD G+PG  GD G+PG +GQ G PG+
Sbjct: 2113 KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGL 2154



 Score =  369 bits (948), Expect = e-102
 Identities = 235/572 (41%), Positives = 292/572 (51%), Gaps = 77/572 (13%)

Query: 425  GFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQ------DGKP 478
            G  GE    P + G        P G  GL GP G  GL G  G PG PGQ       G P
Sbjct: 2204 GLKGE----PGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAP 2259

Query: 479  GYQGIAGTPGVPGSPGIQGARGLP---GYKGEPGRDGDKGDR--GLPGFPGLHGMPGS-- 531
            G  G +G  G  GSPG+ G+ GLP   G KGEPG  G  G    GLPG  G  G PG   
Sbjct: 2260 GRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA 2319

Query: 532  ---KGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGE 588
                GE GAKGD+G P   G +G KGE G AG PG PG  G+ G  G  G  G PG  G 
Sbjct: 2320 GDLVGEPGAKGDRGLP---GPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GV 2375

Query: 589  AGSPGAPGQDGTRGEPGIPGFPGNRGLM------GQKGEIGPPGQQGKKGAPGMPGLMGS 642
             GSPG PG  G +G+ G+PG PG  G++      G +GE+G PG  G++G  G PG  G 
Sbjct: 2376 PGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435

Query: 643  NGSPGQPGTPGS---------KGSKGEPGIQGMPGASGLKGEPGATGSPGEP------GY 687
             G  G PG PGS         KG KG+PG+ G+PG  G +GEPG  G  G P      G 
Sbjct: 2436 PGPLGPPGPPGSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGL 2494

Query: 688  MGLPGIQGKKGDKGNQGEKGIQGQKGEN----------GRQGIPGQQGIQGHHGAKGERG 737
             G PG +G++G+KG+ G  G++G KG++          G +G  G++G +G  G KG RG
Sbjct: 2495 TGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRG 2554

Query: 738  EKGEPGVRGA---IGSKGESGVDGLMGPAGPKGQPGD---PGPQGPPGLDGKPGREFSEQ 791
            + G+PG +G+    G KG +G+ GL G  GP+GQPG    PG  G PG DG PG    + 
Sbjct: 2555 DNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKG 2614

Query: 792  FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRD 851
             +  +    ++ +  V    G     D      G  G PG PG  G +G  G PG+PG+ 
Sbjct: 2615 DVGFMGPRGLKGERGVKGACG----LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQS 2670

Query: 852  GVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-------FGYPGEQGPPGPPGPEGPPGIS 904
            G PG  G+ G  G RG  G PG  G++G +G        G+PG  G  G  GP GPPG  
Sbjct: 2671 GAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPG-- 2728

Query: 905  KEGPPGDPGLPGKDGDHGKPG--IQGQPGPPG 934
              GP G  GL G+ G+ G PG  + G PG PG
Sbjct: 2729 SVGPRGPEGLQGQKGERGPPGERVVGAPGVPG 2760



 Score =  368 bits (944), Expect = e-101
 Identities = 242/605 (40%), Positives = 283/605 (46%), Gaps = 116/605 (19%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPG-------------QPGQDGKPGYQGIAGTPGVPGSPG- 494
            G PG  GPKGD G PG PG PG             +PG  G+ G +G  G PG+PG+PG 
Sbjct: 1685 GSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGE 1744

Query: 495  --IQGARGLPGYKGEPG---RDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGK 549
              I+G RG PG +G+PG     G+KGDRG PG  G  G+ G  G  G  G  G+ G  G 
Sbjct: 1745 RGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGD 1804

Query: 550  KGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGF 609
             G  G  G  G  GLPGP+G PG  GK G  G PG  G+ G PG PG+DG +GE G  G 
Sbjct: 1805 PGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGA 1864

Query: 610  PGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG--SNGSPGQPGTPGSKGSKGEPGI---Q 664
             G  G  G KGE G PG  G +G PG+PG +G    G PG PG  G KG +GE G    Q
Sbjct: 1865 SGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQ 1924

Query: 665  GMPGASGLKGEPGAT--------------------------------------------- 679
            G+PG  GL+GEPG+                                              
Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984

Query: 680  ---GSPGEPGYMGLPGIQGKKGDKGNQGEKGI-------QGQKGENGRQGIPGQQGIQGH 729
               G PG+ G +G PG +G KGD+G+ G +G        +G  G +G  G PG+ GI G 
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044

Query: 730  HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGP--------PGLD 781
             G  G  GE G PG RG  G KGE G  G  GP G  G PG PGP GP        PGL 
Sbjct: 2045 PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLS 2104

Query: 782  GK---PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP 838
            G+   PG + ++           +    V    G  R       Q G+PG+PG  G  GP
Sbjct: 2105 GEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGD-RGEPGPRGQDGNPGLPGERGMAGP 2163

Query: 839  EG------PRGLPGL------PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYP 886
            EG      PRG PG       PG  G PGL G  G  G  GLKG PG  G  G    G  
Sbjct: 2164 EGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPT 2223

Query: 887  GEQGPPGPP------GPEGPPGI-------SKEGPPGDPGLPGKDGDHGKPGIQGQPGPP 933
            G  G PGPP      GP+G PG+        K G PG  G  GKDGD G PG+ G PG P
Sbjct: 2224 GAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLP 2283

Query: 934  GICDP 938
            G   P
Sbjct: 2284 GPVGP 2288



 Score =  365 bits (938), Expect = e-101
 Identities = 227/535 (42%), Positives = 262/535 (48%), Gaps = 77/535 (14%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
            PPG  GL G  G PG+PG PG  G  G+ G+PG +G  G  G  G  G  G  GLPG  G
Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085

Query: 507  EPGRDGDK-----------GDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGE 555
             PG  G K           G++G PG  G  G PGS G+ G KGD+G PG  G +G  G 
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145

Query: 556  KGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGL 615
            +G  G PGLPG  G  G  GK GL G  G  G  G  G PG  G  G  G  G  G  GL
Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205

Query: 616  MGQKGEIGPPGQ--QGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLK 673
             G+ GE GPPG+   G  GA G+PG  G +G  G  G+PG  G  GE G  G PG  G  
Sbjct: 2206 KGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGAS 2265

Query: 674  GEPGATGSPGEPGYMGLPGIQGKKGDKG-----NQGEKGIQGQKGENGRQG-----IPGQ 723
            G+ G  GSPG PG  GLPG  G KG+ G      Q   G+ G KGE G  G     + G+
Sbjct: 2266 GKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE 2325

Query: 724  QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQ-----PGDPGPQGPP 778
             G +G  G  G RGEKGE G  G  G  GE G  G  GP G KG      PG PGP GPP
Sbjct: 2326 PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPP 2385

Query: 779  GLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPI-- 836
            G+ G  G                   LP L  +  +          G PG  GP G +  
Sbjct: 2386 GVKGDLG-------------------LPGLPGAPGV---------VGFPGQTGPRGEMGQ 2417

Query: 837  -GPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYP---GEQGPP 892
             GP G RGL G PGR+G+PG +G PG PG  G  G  G  G+KG  G G P   GE+G P
Sbjct: 2418 PGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEP 2477

Query: 893  ------GPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQP-------GPPG 934
                  G PG EGP G++  GPPG  G  G+ GD G  G++G         GPPG
Sbjct: 2478 GIRGEDGRPGQEGPRGLT--GPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG 2530



 Score =  364 bits (935), Expect = e-100
 Identities = 231/567 (40%), Positives = 274/567 (48%), Gaps = 107/567 (18%)

Query: 447  PPGKPG--LQGPKGDPGLPGNPG------YPGQPGQDGKPG------------------- 479
            PPG PG  ++G KGD G  G PG       PG+PG  G PG                   
Sbjct: 1390 PPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGD 1449

Query: 480  -YQGIAGTPGVPGSPGIQGARGLP---------GYKGEPGRDGDKGDRGLPGFPGLHGMP 529
               G  G PG PGSPG QG RG P         G+ G  G  G+KG+RG PG  G  G+P
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509

Query: 530  GSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPA-----GEPGRHGKDGLMGSPG 584
            G  G  GAKG +G PG  G++G KGE G  G P + GPA     GE G  G  G  G+ G
Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATG 1569

Query: 585  FKGEAGSPG--APGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGS 642
             +GE G PG   PG  G +G+PG  G  G  G  G  G+ GPPG++G  G PG PG +G 
Sbjct: 1570 VQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGP 1629

Query: 643  NGSPGQ---------PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGI 693
             G  G+         PG PG  G  GE G++G PG  G  GE G  G PGE G  G PG 
Sbjct: 1630 RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGS 1689

Query: 694  QGKKGD----------------------KGNQGEKGIQGQKGENGRQGIPGQQGIQGHHG 731
             G KGD                      KG  G++G +G +G  G  G+PG  G +G  G
Sbjct: 1690 SGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEG 1749

Query: 732  AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQ 791
             +G  G +G+PGVRG  G KG+ G  GL G +G  G+PG  GP GP G  GK G      
Sbjct: 1750 FRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAG------ 1803

Query: 792  FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRD 851
                   D  R  LP L              + G PG  GPPG  G  G  G PGL G++
Sbjct: 1804 -------DPGRDGLPGL------------RGEQGLPGPSGPPGLPGKPGEDGKPGLNGKN 1844

Query: 852  GVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGPPGISKEG 907
            G PG  G  GR G +G  G  GR G  G +G     G  G QGPPG PGP GPPG   +G
Sbjct: 1845 GEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG---QG 1901

Query: 908  PPGDPGLPGKDGDHGKPGIQGQPGPPG 934
             PG PG  G  GD G+ G +G+ G PG
Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGEQGLPG 1928



 Score =  364 bits (935), Expect = e-100
 Identities = 235/605 (38%), Positives = 282/605 (46%), Gaps = 118/605 (19%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKG 506
            PPG  G  G KGDPG PG PG  G  G+DG+ G +G  G PG PG PG  G RGL G  G
Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPG 1664

Query: 507  EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD-------------------KGSPGFY 547
              G  G+KGD+G PG  G +G PGS G  G +G+                   KG PG  
Sbjct: 1665 VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDR 1724

Query: 548  GKKGAKGEKGNAGFPGLPG---------------------PAGEPGRHGKDGLMGSPGFK 586
            G++G +G KG+ G PG PG                     PAGE G  G  GL G  G  
Sbjct: 1725 GQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784

Query: 587  GEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643
            G+ G+ G  G +G  G   +PG  G PG RG  G  G  GPPG  GK G  G PGL G N
Sbjct: 1785 GKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKN 1844

Query: 644  GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATG------SPGEPGYMGLPGIQGKK 697
            G PG PG  G KG KG+ G  G  G  G KGE GA G       PG PG +G PG QG  
Sbjct: 1845 GEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG-QGFP 1903

Query: 698  GDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGA------------------------- 732
            G  G  G KG +G+ G  G QG+PG++G++G  G+                         
Sbjct: 1904 GVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETW 1963

Query: 733  -----------------KGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG----D 771
                             KG+ GE+G PG  G IG  GE G+ G  G  GP+G PG    +
Sbjct: 1964 DESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGE 2023

Query: 772  PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPG 831
             GP GP GL G+PG+        +    V  A  P        +       + G PG+PG
Sbjct: 2024 RGPPGPSGLAGEPGKPGIPGLPGRA-GGVGEAGRPGERGERGEKGERGEQGRDGPPGLPG 2082

Query: 832  PPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPG 887
             PGP GP GP+     PG    PGL G  G PG++G KG PG NG++G +G     G  G
Sbjct: 2083 TPGPPGPPGPKVSVDEPG----PGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG 2138

Query: 888  EQGPPGPPGPEGPPGISKE-------------GPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            ++G PGP G +G PG+  E             GP G PG  G  GD G PG  G  GP G
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 935  ICDPS 939
               PS
Sbjct: 2199 PQGPS 2203



 Score =  359 bits (921), Expect = 8e-99
 Identities = 233/582 (40%), Positives = 276/582 (47%), Gaps = 104/582 (17%)

Query: 441  PAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARG 500
            P P + P G+ G  G KGD G PG+PG P      GK G +G+ G PGV G  G +G +G
Sbjct: 1624 PGP-VGPRGRDGEVGEKGDEGPPGDPGLP------GKAGERGLRGAPGVRGPVGEKGDQG 1676

Query: 501  LP---GYKGEPGRDGDKGDRGLPGFPG-------------LHGMPGSKGEMGAKGDKGSP 544
             P   G  G PG  G KGDRG PG PG               G PG +G+ G +G KG P
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP 1736

Query: 545  GFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGK------------DGLMGSPGFKGEAGSP 592
            G     GA GE+G  GF G PGP G+PG  G             DG  G  G  G AG  
Sbjct: 1737 GL---PGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS 1793

Query: 593  GAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTP 652
            G  G  G  G+PG  G PG RG  G  G  GPPG  GK G  G PGL G NG PG PG  
Sbjct: 1794 GPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED 1853

Query: 653  GSKGSKGEPGIQGMPGASGLKGEPGA------TGSPGEPGYMGLPGIQGKKGDKGNQGEK 706
            G KG KG+ G  G  G  G KGE GA       G PG PG +G PG QG  G  G  G K
Sbjct: 1854 GRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG-QGFPGVPGGTGPK 1912

Query: 707  GIQGQKGENGRQGIPGQQGIQG-------------------------------------- 728
            G +G+ G  G QG+PG++G++G                                      
Sbjct: 1913 GDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLP 1972

Query: 729  ----HHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQP----GDPGPQGPPGL 780
                  G KG+ GE+G PG  G IG  GE G+ G  G  GP+G P    G+ GP GP GL
Sbjct: 1973 VPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGL 2032

Query: 781  DGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG 840
             G+PG+      +      V  A  P        +       + G PG+PG PGP GP G
Sbjct: 2033 AGEPGKP-GIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091

Query: 841  PRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF----GYPGEQGPPGPPG 896
            P+     PG    PGL G  G PG++G KG PG NG++G +G     G  G++G PGP G
Sbjct: 2092 PKVSVDEPG----PGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG 2147

Query: 897  PEGPPGISKE----GPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
             +G PG+  E    GP G PGL G  G  G  G  G PGPPG
Sbjct: 2148 QDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPG 2189



 Score =  320 bits (821), Expect = 3e-87
 Identities = 204/500 (40%), Positives = 241/500 (48%), Gaps = 92/500 (18%)

Query: 424  PGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI 483
            PG +G+    P   G    P +  PG PG  GP   PG+ G+ G PG PG  G  G+ G 
Sbjct: 2353 PGEDGQ-KGAPGPKGFKGDPGVGVPGSPGPPGP---PGVKGDLGLPGLPGAPGVVGFPGQ 2408

Query: 484  AGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGS 543
             G  G  G PG  G RGL    G PGR+G  G  G PG PG  G PG+    G KGDKG 
Sbjct: 2409 TGPRGEMGQPGPSGERGL---AGPPGREGIPGPLGPPGPPGSVGPPGAS---GLKGDKGD 2462

Query: 544  PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGE 603
            PG     G  G +G  G PG+ G  G PG+ G  GL G PG +GE G  G  G  G +G+
Sbjct: 2463 PGV----GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD 2518

Query: 604  PG----IPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKG 659
             G    I G PG RG  G  GE GP G  G KG  G  G  G  GS G+   PG KGS G
Sbjct: 2519 KGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGE---PGDKGSAG 2575

Query: 660  EPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGD---------KGNQGEK---G 707
             PG++G+ G  G  G  G  G PG PG  G+PGI+G+KGD         KG +G K   G
Sbjct: 2576 LPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACG 2635

Query: 708  IQGQKGENGRQGIPGQQGIQGHHGAKGE---RGEKGEPGVRGAIGSKGESGVDGLMGPAG 764
            + G+KG+ G  G PG+ G+ GH G  GE    G+ G PG  G IG KG+ G D   G  G
Sbjct: 2636 LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFD---GQPG 2692

Query: 765  PKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQH 824
            PKG  G+ G +G PG+ G PG   ++                                  
Sbjct: 2693 PKGDQGEKGERGTPGIGGFPGPSGND---------------------------------- 2718

Query: 825  GSPGIPGPPGPIGPEGPRGLPGLPGRDGVPG--LVGVPGRPGVRGLKGLPGRNGEKGSQG 882
            GS G PGPPG +GP GP GL G  G  G PG  +VG PG PG  G +             
Sbjct: 2719 GSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGER------------- 2765

Query: 883  FGYPGEQGPPGPPGPEGPPG 902
                GEQG PGP GP G  G
Sbjct: 2766 ----GEQGRPGPAGPRGEKG 2781



 Score =  283 bits (725), Expect = 4e-76
 Identities = 166/380 (43%), Positives = 199/380 (52%), Gaps = 26/380 (6%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            + GF G+   GP      P P     G+ GL GP G  G+PG  G PG PG  G PG  G
Sbjct: 2402 VVGFPGQ--TGPRGEMGQPGPS----GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASG 2455

Query: 483  IAGTPGVPGS--PGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGA--- 537
            + G  G PG   PG +G RG PG +GE GR G +G RGL G PG  G  G KG++G+   
Sbjct: 2456 LKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGL 2515

Query: 538  KGDKGS-------PGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAG 590
            KGDKG        PG  G KG  GE+G  G  G  GP G+ G  G  G  G PG KG AG
Sbjct: 2516 KGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAG 2575

Query: 591  SPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPG 650
             PG  G  G +G+PG  G PG+ G  G+ G  G  G++G  G  G  GL G  G  G  G
Sbjct: 2576 LPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACG 2635

Query: 651  TPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQG 710
              G KG KGE G  G PG +G KGE G  G PG+ G  G  G+ G KGD+G  G+ G +G
Sbjct: 2636 LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKG 2695

Query: 711  QKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQ-- 768
             +GE G +G P   GI G  G  G  G  G PG  G++G +G  G+ G  G  GP G+  
Sbjct: 2696 DQGEKGERGTP---GIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERV 2752

Query: 769  ---PGDPGPQGPPGLDGKPG 785
               PG PG  G  G  G+PG
Sbjct: 2753 VGAPGVPGAPGERGEQGRPG 2772



 Score =  268 bits (685), Expect = 2e-71
 Identities = 160/369 (43%), Positives = 189/369 (51%), Gaps = 25/369 (6%)

Query: 424  PGFNGEC-LNGPSDVGSTPAPC--------ICPPGKPGLQGPKGDPG--LPGNPGYPGQP 472
            PG +GE  L GP      P P         + PPG  GL+G KGDPG  LPG  G  G+P
Sbjct: 2418 PGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEP 2477

Query: 473  GQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGD----------RGLPGF 522
            G  G+ G  G  G  G+ G PG +G RG  G  G  G  GDKGD          RG  G 
Sbjct: 2478 GIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGD 2537

Query: 523  PGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGS 582
             G  G  G  G+ G +GD G PG  G KG  G+KG+AG PGL G  G  G+ G  G+ G 
Sbjct: 2538 MGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGD 2597

Query: 583  PGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGS 642
            PG  G+ G PG  G+ G  G  G  G  G RG+ G  G  G  G +G+ G PG PGL G 
Sbjct: 2598 PGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGH 2657

Query: 643  NGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN 702
             G  G+PG PG  G+ G+ G+ G  G  G  G+PG  G  GE G  G PGI G  G  GN
Sbjct: 2658 KGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGN 2717

Query: 703  QGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGP 762
             G  G  G  G  G +G  G QG +G  G  GER   G PGV GA G +GE    G  GP
Sbjct: 2718 DGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGER-VVGAPGVPGAPGERGE---QGRPGP 2773

Query: 763  AGPKGQPGD 771
            AGP+G+ G+
Sbjct: 2774 AGPRGEKGE 2782



 Score =  252 bits (644), Expect = 1e-66
 Identities = 173/432 (40%), Positives = 203/432 (46%), Gaps = 81/432 (18%)

Query: 547  YGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGI 606
            Y  KG KGE G  G  G  GP G+PG          PG  G  G  G PG    +GE G 
Sbjct: 1250 YCPKGQKGEPGEMGLRGQVGPPGDPGL---------PGRTGAPGPQGPPGSATAKGERGF 1300

Query: 607  PGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGM 666
            PG  G  G  G+ G  G PG  G KG+PG+PG        G PG  G +G KGEPG  G 
Sbjct: 1301 PGADGRPGSPGRAGNPGTPGAPGLKGSPGLPG------PRGDPGERGPRGPKGEPGAPGQ 1354

Query: 667  ------PGASGLKGEPGATGSPG------EPGYMGLPGIQGK--KGDKGNQGEKGIQGQK 712
                  PG  G KG+PG +G PG      +PG  G PG+ G   KGDKG++GE+G  G  
Sbjct: 1355 VIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGP- 1413

Query: 713  GENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDP 772
            GE G    PG+ G+ G  G+ G +G  G PG +G    KG+S  DG  G  G  G PG+ 
Sbjct: 1414 GEGGIA--PGEPGLPGLPGSPGPQGPVGPPGKKG---EKGDSE-DGAPGLPGQPGSPGEQ 1467

Query: 773  GPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGP 832
            GP+GPPG  G  G                             R     L + G  G  GP
Sbjct: 1468 GPRGPPGAIGPKGD----------------------------RGFPGPLGEAGEKGERGP 1499

Query: 833  PGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG---FGYPGEQ 889
            PGP    G RGLPG+ GR G  G  G PG  G +G KG PGR G+    G    G  GE+
Sbjct: 1500 PGP---AGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEK 1556

Query: 890  GPPGPPGPEGPPGISKE-GP-----PGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFS 943
            G  GP GP G  G+  E GP     PGDPG  G  GD G  G+ G+ GPPG   P     
Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPP---- 1612

Query: 944  VIARRDPFRKGP 955
               + DP R GP
Sbjct: 1613 -GEKGDPGRPGP 1623



 Score =  118 bits (295), Expect = 3e-26
 Identities = 78/261 (29%), Positives = 134/261 (51%), Gaps = 13/261 (4%)

Query: 11  VLVLLLQNSVLAEDGEVRSSCRTAPT-------DLVFILDGSYSVGPENFEIVKKWLVNI 63
           +LV  L   +LAE   VR+  R   T       D+VF+LDGS S+G  NF  V+ +L  +
Sbjct: 5   LLVAALCAGILAEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGL 64

Query: 64  TKNFD--IGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQ 121
              F      + ++   VQYSD P  E  L +  SG  +  A+  + Y GGNT+TG AI 
Sbjct: 65  VLPFSGAASAQGVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAIL 124

Query: 122 FALDYLFAK--SSRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAEL 179
              D++F    +   + K+ +++TDGKSQD V  AAQ  +   + LFA+G+    +  EL
Sbjct: 125 HVADHVFLPQLARPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGI-KNADPEEL 183

Query: 180 RAIANKPSSTYVFYVEDYIAISKIREVMKQKLCEES-VCPTRIPVAARDERGFDILLGLD 238
           + +A++P+S + F+V D+  +  +  ++ +++C  +   P   P         D++L   
Sbjct: 184 KRVASQPTSDFFFFVNDFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEP 243

Query: 239 VNKKVKKRIQLSPKKIKGYEV 259
            ++ ++ +   +   + GY+V
Sbjct: 244 SSQSLRVQWTAASGPVTGYKV 264



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 42/176 (23%), Positives = 75/176 (42%), Gaps = 15/176 (8%)

Query: 69   IGPKFIQVGVVQYSDYPVLEIPL-GSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYL 127
            +GP+ +QVG++ YS  P    PL GS+D G  L    +           G A+  A  Y+
Sbjct: 1086 LGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYM 1145

Query: 128  FAKSS----RFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIA 183
             A  +    + +  + V+L D   + D+    + A+ S + +  +G+    +  +LR +A
Sbjct: 1146 LAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAG-ADPEQLRRLA 1204

Query: 184  NKPSSTYVFY-VEDYIAISKIREVMKQKLCEESV--------CPTRIPVAARDERG 230
                S   F+ V+D  ++ +    +   LC+ S         CP   P   + E G
Sbjct: 1205 PGMDSVQTFFAVDDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPG 1260



 Score = 33.5 bits (75), Expect = 0.98
 Identities = 18/44 (40%), Positives = 20/44 (45%)

Query: 895  PGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            P PE  P    +G  G+PG  G  G  G PG  G PG  G   P
Sbjct: 1242 PRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGP 1285


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score =  380 bits (975), Expect = e-105
 Identities = 251/608 (41%), Positives = 289/608 (47%), Gaps = 103/608 (16%)

Query: 434  PSDVGSTPAPCICP--------PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAG 485
            P   G T  PCI P        PG PG  GPKG  GLPG PG PG  G  G+PG  G+  
Sbjct: 648  PGSKGIT-LPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVH 706

Query: 486  TPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPG--------SKGEMGA 537
             P +PG PG +G +GLPG+ G PG+DG  G  G PG PG  G  G        + GE G 
Sbjct: 707  LPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGL 766

Query: 538  KGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ 597
            +G  G  GF G  G  G KG  G PGL GP GE G  G  G +G PG  G +G  G  G+
Sbjct: 767  QGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGK 826

Query: 598  DGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM------PGLMGSNGSPGQPGT 651
             G  G PG PG  G+ G  G +G+ GPPG   KKG PG+      PGL+G  GSPG PG 
Sbjct: 827  SGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGV 886

Query: 652  PG------SKGSKGE---------PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGK 696
             G       KG KG          PG+ G+PG  GLKG PG+TG  G  G  G PG +G 
Sbjct: 887  AGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD 946

Query: 697  ---------------------KGDKGNQGEKGI------QGQKGENGRQGIPGQQGIQGH 729
                                 KGDKG+QG  G       +G KGE GR G PG  G  G 
Sbjct: 947  RGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGL 1006

Query: 730  HGA-KGERGEKGEPG---VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPG 785
             G  KG  G+ G PG   +RG  G KG SG+ G  G  G  G  G  G  G PG  G PG
Sbjct: 1007 PGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPG 1066

Query: 786  REFSEQFIRQVCTDVIRAQLP-------VLLQSGRIRNC--------DHCLSQHGSPGIP 830
             +       ++         P          + G I N         D  +   G  G+P
Sbjct: 1067 LKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLP 1126

Query: 831  GPPGPIGPEGPRGLPGLPGRDG---------VPGLVG---VPGRPGVRGLKGLPGRNGEK 878
            G PG  G  G RG PGLPG  G          PGL+G    PG PG+ GL GLPG  G  
Sbjct: 1127 GAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTH 1186

Query: 879  GSQG---FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQ---PGP 932
            G+ G    G PG  G PGP G +G PGI   G PG PGL G+ GD G PG+QG    PG 
Sbjct: 1187 GTPGPSITGVPGPAGLPGPKGEKGYPGIG-IGAPGKPGLRGQKGDRGFPGLQGPAGLPGA 1245

Query: 933  PGICDPSL 940
            PGI  PSL
Sbjct: 1246 PGISLPSL 1253



 Score =  375 bits (963), Expect = e-103
 Identities = 227/526 (43%), Positives = 265/526 (50%), Gaps = 71/526 (13%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEP 508
            GKPGL GPKG+ G PG PG  GQPG  G  G  GI G  G+PG+PG  G  G PG KG  
Sbjct: 789  GKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTR 848

Query: 509  GRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPG------FYGKKGAKGEKGNAGFP 562
            G+ G  G     G PGL G+PG+ G +G KG  GSPG        G KG KG  G  GFP
Sbjct: 849  GKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFP 908

Query: 563  GLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNR--------- 613
            G+PG  G PG  G  G+ GS G  G +G  G PG+ G RG PG  G P  R         
Sbjct: 909  GIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLK 968

Query: 614  ---------------GLMGQKGEIGPPGQQGKKGAPGMPGLM-GSNGSPGQPGTPGSKGS 657
                           G  G KGE G PG  G  GAPG+PG++ G +G PG PG  G +G 
Sbjct: 969  GDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL 1028

Query: 658  ---KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN-QGEKGIQGQKG 713
               KG  GI G PG  G  G  G  GSPG PG  GLPG++G  G      G  G +GQ G
Sbjct: 1029 PGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPG 1088

Query: 714  ENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPG 773
            E+G +G  G+ G+ G+ G  G +GE G+ GV G +G  G  G  G+ G  G  G PG  G
Sbjct: 1089 ESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSG 1148

Query: 774  PQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPP 833
             QG  G  G PG    + F             P L               HG  G+PG  
Sbjct: 1149 HQGAIGPLGSPGLIGPKGF----------PGFPGL---------------HGLNGLPGTK 1183

Query: 834  GPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVR-GLKGLPGRNGEKGSQGFGYPGEQGPP 892
            G  G  GP  + G+PG  G+PG  G  G PG+  G  G PG  G+KG +GF  PG QGP 
Sbjct: 1184 GTHGTPGP-SITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGF--PGLQGPA 1240

Query: 893  GPPGPEGPPGISKE----GPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            G PG    PGIS      G PGDPG PG DG+ G+PG  G PGPPG
Sbjct: 1241 GLPGA---PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPG 1283



 Score =  365 bits (937), Expect = e-100
 Identities = 235/581 (40%), Positives = 282/581 (48%), Gaps = 79/581 (13%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            +PG  G+   G   +   P      PG PGL G  G PGLPG  G PG  G+DG PG QG
Sbjct: 589  LPGDGGQGFPGEKGLPGLPGEK-GHPGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQG 646

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGA----- 537
            + G+ G+     I G+ G  G+ G PG  G KG RGLPG PG  G  GSKGE G+     
Sbjct: 647  LPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVH 706

Query: 538  ----------KGDKGSPGFYGKKGAKGEKGNAGFPGLPGPA-----------GEPGRHGK 576
                      +G+KG PGF G  G  G  G  G PGLPG             G PG  G 
Sbjct: 707  LPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGL 766

Query: 577  DGLMGSPGFKGEAGSP------GAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGK 630
             GL G  GF G++G P      G PG  G +GE G PG PG  G  G  G  GP G +GK
Sbjct: 767  QGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGK 826

Query: 631  KGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGAT---GSPGEPGY 687
             G PG PG  G +G PG+ GT G KG  G    +G+PG  GL G PG     GSPG PG 
Sbjct: 827  SGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGV 886

Query: 688  MGLPGIQGKKGDKGN------QGEKGIQGQKGENGRQGIP---GQQGIQGHHGAKGERGE 738
             GLP + G KG+KG+       G  G+ G  G  G +GIP   G+ G  G  G  GE+G+
Sbjct: 887  AGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD 946

Query: 739  KGEPG---------------VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGK 783
            +G PG               ++G  GS+G +G +G  GP G KG+ G PGP G PG  G 
Sbjct: 947  RGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGL 1006

Query: 784  PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRG 843
            PG          +   V     P       IR         G  G PG PG  G +G RG
Sbjct: 1007 PG----------IIKGVSGKPGPPGFMG--IRGLPGLKGSSGITGFPGMPGESGSQGIRG 1054

Query: 844  LPGLPGRDGVPGLVGVPGR----PGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPE 898
             PGLPG  G+PGL G  G+     G  G KG PG +G KG++G  G  G  G PG  G +
Sbjct: 1055 SPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGED 1114

Query: 899  GPPGISKE-GPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            G  G+S + G PG PG PG  G  G+PG+ G  G  G   P
Sbjct: 1115 GKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGP 1155



 Score =  361 bits (926), Expect = 2e-99
 Identities = 237/583 (40%), Positives = 280/583 (48%), Gaps = 103/583 (17%)

Query: 423 IPGFNGECLNGPSDVGSTPAP--------CICPPGKPGLQGPKGDPGLPGNPGYPGQPGQ 474
           +PGF G  +NG       P P        C    G  G  GP G PGL G PG PGQ G 
Sbjct: 99  VPGFLG--INGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGS 156

Query: 475 DGKP-----GYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMP 529
            G P      ++G+ G PG+PG  GI G +G PG+ G  G  G  G +G PG PG  G  
Sbjct: 157 KGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPD 216

Query: 530 GS-----KGEMGAKGDKGSPGFYGKKGAKGEKGNAGFP-GLPGPAGEPGRHGKDGLMGSP 583
           G+     +GE G KGD G PG  G   + GE    GFP G  G  GEPG  G  G+ G P
Sbjct: 217 GNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPP 276

Query: 584 GFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG-- 641
           GF G     G  G+ G +GE GIPG PG RG MG +G  GPPGQQGKKG  G PGL G  
Sbjct: 277 GFPG----LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQ 332

Query: 642 ------------------------SNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
                                    +G+PG PG PG  G KG+ GIQG+ G SG+ G P 
Sbjct: 333 GIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPA 392

Query: 678 ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGE-- 735
            +G PG  G  G PG+   KGD+GN G   I G  G  GR G+PG  G  G    + E  
Sbjct: 393 LSGVPGALGPQGFPGL---KGDQGNPGRTTI-GAAGLPGRDGLPGPPGPPGPPSPEFETE 448

Query: 736 ---RGEKGEPGVRGAIGSKGESGVDGLMGPAG---------PKGQPGDPGPQGPPGLDGK 783
                E G PG+RG  G KG  G+ G+ G +G           G PG+PGP GP GL G 
Sbjct: 449 TLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGL 508

Query: 784 PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPR- 842
           PG                      L  +   R         G+PG+ GP GP GP+G + 
Sbjct: 509 PG----------------------LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKG 546

Query: 843 --------GLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGP 894
                   G+PG  G  G  G  GV G PG  G+ GLPG  G  G  G G+PGE+G PG 
Sbjct: 547 EPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGL 606

Query: 895 PGPE---GPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           PG +   GPPG+   G PG PG  G  GD GK G+ GQ G PG
Sbjct: 607 PGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPG 649



 Score =  356 bits (914), Expect = 5e-98
 Identities = 216/509 (42%), Positives = 266/509 (52%), Gaps = 52/509 (10%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGY-QGIAGTPGVPGS------PGIQGARGL 501
            G  G  GP+GD G  G PG PG PG  G PG  +G++G PG PG       PG++G+ G+
Sbjct: 978  GSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGI 1037

Query: 502  PGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD-KGSPGFYGKKGAKGEKGNAG 560
             G+ G PG  G +G RG PG PG  G+PG KG+ G   +  GSPG  G+ G  G KG  G
Sbjct: 1038 TGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKG 1097

Query: 561  FPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKG 620
              GL G  G PG  G+DG +G  G  G  G+PG PG  G RGEPG+PG  G++G +G   
Sbjct: 1098 RDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGP-- 1155

Query: 621  EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSK--GEPGIQGMPGASGLKGEPG- 677
             +G PG  G KG PG PGL G NG PG  GT G+ G    G PG  G+PG  G KG PG 
Sbjct: 1156 -LGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGI 1214

Query: 678  ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGEN------GRQGIPGQQGIQGHHG 731
              G+PG+PG   L G +G +G  G QG  G+ G  G +      G+ G PG+ G+ G  G
Sbjct: 1215 GIGAPGKPG---LRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG 1271

Query: 732  AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQ 791
              G  G  G PG     G  G+ G  G+ GP GPKG  G PG  G PG  G  G      
Sbjct: 1272 RPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKG------ 1325

Query: 792  FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRD 851
                     +R +   +   G++          G PG PG  G  GP G  GL G PG+ 
Sbjct: 1326 ---------MRGEPGFMGTPGKV-------GPPGDPGFPGMKGKAGPRGSSGLQGDPGQT 1369

Query: 852  GVPGLVGVPGRP-GVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPP 909
                 V VP  P G+ G+ G+PG  G+ G+QG  G  G +G PG PG +GP G+   GPP
Sbjct: 1370 PTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLP--GPP 1427

Query: 910  G---DPGLPGKDGDHGKPGIQGQPGPPGI 935
            G   DPGLPG  G  G  G  GQ GP G+
Sbjct: 1428 GALGDPGLPGLQGPPGFEGAPGQQGPFGM 1456



 Score =  355 bits (912), Expect = 9e-98
 Identities = 236/597 (39%), Positives = 273/597 (45%), Gaps = 129/597 (21%)

Query: 448  PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
            PG PGL G KG PG PG  G P   G  G+ G  G  G PG+PG PGI G RGL G  G 
Sbjct: 869  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 928

Query: 508  PGRDGDKGDRGLPGFPGLHGMPGS---------------KGEMGAKGDKGSPGFYGKKGA 552
             G+ G  G  G PG  G  G PG                KG+ G++G  GS GF G +G 
Sbjct: 929  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGD 988

Query: 553  KGEKGNAGFPGLPGP----------AGEPGRHGKDGLMGSPGFKGEAGS---PGAPGQDG 599
            KGE G  G PGLPG           +G+PG  G  G+ G PG KG +G    PG PG+ G
Sbjct: 989  KGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESG 1048

Query: 600  TRGEPGIPGFPGNRGLMGQKGEIGP-------------PGQQGKKGAPGMPGLMGSNGSP 646
            ++G  G PG PG  GL G KG+ G              PG+ G KG  G  GL+G+ G P
Sbjct: 1049 SQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFP 1108

Query: 647  GQPGTPGSKGSKGE---PGIQGMPGASGLKGEPGATGSPGEPGY---MGLPGIQGKKGDK 700
            G  G  G  G  G+   PG  G PG +G++GEPG  GS G  G    +G PG+ G KG  
Sbjct: 1109 GNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFP 1168

Query: 701  GNQGEKGIQGQKGENGRQGIPGQQ--GIQGHHGAKGERGEKGEPGVR-------GAIGSK 751
            G  G  G+ G  G  G  G PG    G+ G  G  G +GEKG PG+        G  G K
Sbjct: 1169 GFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQK 1228

Query: 752  GESGVDGLMGPAGPKGQPG---------DPGPQGPPGLDGKPGREFSEQFIRQVCTDVIR 802
            G+ G  GL GPAG  G PG          PG  G PGLDG+ GR                
Sbjct: 1229 GDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGP------------- 1275

Query: 803  AQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGL--------------- 847
            A  P     G   N        G PG PG PGP GP+G +G+PG                
Sbjct: 1276 AGPPG--PPGPSSN----QGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGE 1329

Query: 848  PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG------------------------- 882
            PG  G PG VG PG PG  G+KG  G  G  G QG                         
Sbjct: 1330 PGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDG 1389

Query: 883  ----FGYPGEQGPPGPPGPEGPPGI-SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                 G PG QGP G  G +G PGI  K+GP G PG PG  GD G PG+QG PG  G
Sbjct: 1390 IPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEG 1446



 Score =  350 bits (898), Expect = 4e-96
 Identities = 231/577 (40%), Positives = 265/577 (45%), Gaps = 104/577 (18%)

Query: 423  IPGFNGECLNGPSDVGSTPAPC-----ICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK 477
            +PG  G    G    G    P      + P G  G +G KG+P L    G PG  G  G 
Sbjct: 508  LPGLKGA--RGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGS 565

Query: 478  PGYQGIAGTPGVPGSPGIQGARGL--------PGYKGEPGRDGDKGDRGLPGFPGLHGMP 529
             G++G+ G PG  G PG+ G  GL        PG KG PG  G+KG  G PG PG +G+P
Sbjct: 566  QGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPG-NGLP 624

Query: 530  GSKGEMGAKGDKGSPGFYGKKGAKGEKGNA---------------GFPGLPGPAGEPGRH 574
            G  G  G  GDKG  G  G++G  G KG                 G PG PGP G  G  
Sbjct: 625  GLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLP 684

Query: 575  GKDGLMGSPGFKGEAGSPG------APGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQ 628
            G  G  GS G KGE GSPG       PG  G RGE G+PGFPG  G  G  G IG PG  
Sbjct: 685  GTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLP 744

Query: 629  GKKGAPGMPGLMGS-NGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGY 687
            G KGA G   + G+ NG+PG+ G  G  G KG  G  G+PG  G+ G+PG  G  GE G 
Sbjct: 745  GSKGATG--DIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGS 802

Query: 688  MGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGA 747
             G PG  G+ G  G+ G  GI   KG++G  G PG  GI GH G KG RG+KG PG    
Sbjct: 803  PGTPGQVGQPGTPGSSGPYGI---KGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVK 859

Query: 748  IGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPV 807
             G  G  G+ G  G  G KG PG PG  G P L G  G + S  F+              
Sbjct: 860  KGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFV-------------- 905

Query: 808  LLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRG 867
                             G PGIPG PG  G  G +G+PG  G+ G  G  G PG  G RG
Sbjct: 906  -----------------GFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRG 948

Query: 868  ------------------LKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGPPGI-- 903
                              LKG  G  G  GS GF    G  GE G PGPPG  G PG+  
Sbjct: 949  NPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPG 1008

Query: 904  ------SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                   K GPPG  G+ G  G  G  GI G PG PG
Sbjct: 1009 IIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPG 1045



 Score =  339 bits (869), Expect = 8e-93
 Identities = 229/602 (38%), Positives = 277/602 (46%), Gaps = 112/602 (18%)

Query: 449 GKP-GLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
           GKP G Q   G        G  G+PG  G  G  G  G  G  G  G++G RG PG  G 
Sbjct: 28  GKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGP 87

Query: 508 PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP 567
            G  GDKG  G+PGF G++G+PG  G+ G +G  G  G  G +GA G  G  G+PGL GP
Sbjct: 88  YGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGP 147

Query: 568 AGEPGRHGKDG--LMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPP 625
            G PG+ G  G  ++    FKG  G PG PG DG  G  G PGFPG  G  G  G  GPP
Sbjct: 148 PGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP 207

Query: 626 GQ--------------QGKKGAPGMPGLMGSNGSPGQPG-------TPGSKGSKGEPGIQ 664
           G               QG+KG  G  GL G  G P   G         G KGSKGEPG +
Sbjct: 208 GPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPK 267

Query: 665 GMPGASGLKGEP--GATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPG 722
           G PG SG  G P  G TG  GE G  G+PG+ G +G  G++G +G  GQ+G+ G  G PG
Sbjct: 268 GFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPG 327

Query: 723 QQGIQGHHGAKGE-----------------RGEKGEPGVRGAIGSKGESGVDGLMGPA-- 763
             G QG  G KG+                  G  G+PGV G  G KG+ G+ GL GP+  
Sbjct: 328 LNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGV 387

Query: 764 -------------GPKGQPGDPGPQ--------------------GPPGLDGKPGREFSE 790
                        GP+G PG  G Q                    GPPG  G P  EF  
Sbjct: 388 PGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFET 447

Query: 791 QFI--RQVCTDVIRAQ--------LPVLLQSGRIRNCDHCLSQHGSPGIPGPPGP----- 835
           + +  ++     +R +        L  +        CD  +   G PG PGPPGP     
Sbjct: 448 ETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIG 507

Query: 836 ----IGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRG---------LKGLPGRNGEKGSQG 882
                G  G RG  G  G  G PGLVG  G  G +G         ++G+PG  G+ GSQG
Sbjct: 508 LPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQG 567

Query: 883 F----GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGP--PGIC 936
           F    G PG+ G PG PG  G PG   +G PG+ GLPG  G+ G PG  G PG   PG+ 
Sbjct: 568 FRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLP 627

Query: 937 DP 938
            P
Sbjct: 628 GP 629



 Score =  336 bits (861), Expect = 7e-92
 Identities = 229/606 (37%), Positives = 280/606 (46%), Gaps = 123/606 (20%)

Query: 425 GFNGECLNGPSDVGSTPAPCICPP---------------GKPGLQGPKGDPGLPGNPGYP 469
           GF GE      DVG  P P   PP               G  G  GPKG PG+ G PG+P
Sbjct: 222 GFQGE-KGVKGDVG-LPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFP 279

Query: 470 GQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMP 529
           G     G  G +G  G  G+PG PG +G  G  G +G PG+ G KG  G PG  G  G+ 
Sbjct: 280 GL----GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIE 335

Query: 530 GSKGEMGAKGD-----------KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDG 578
           G KG++G  G             G+PG  G  G  G KG+ G  GL GP+G PG     G
Sbjct: 336 GQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSG 395

Query: 579 LMGS------PGFKGEAGSPGA--------PGQDGTRGEPGIPG---------------- 608
           + G+      PG KG+ G+PG         PG+DG  G PG PG                
Sbjct: 396 VPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKES 455

Query: 609 -FPGNRGLMGQKGEIGPPGQQGKKG------------APGMPGLMGSNGSPGQPGTPGSK 655
            FPG RG  G KG +G  G +G  G             PG PG  G  G  G PG  G++
Sbjct: 456 GFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGAR 515

Query: 656 GSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGEN 715
           G +G  G QG  GA GL G  G +G  G+ G   L  IQG  GD+G+ G +G +G  GE 
Sbjct: 516 GDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEP 575

Query: 716 GRQGIPGQQGIQG--HHGAKGERGEKGEPGVRGAIGSKGESGV--DGLMGPAGPKGQPGD 771
           G+ G+PG  G+ G    G +G  GEKG PG+ G  G  G  G+  +GL G  GP+G PGD
Sbjct: 576 GKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGD 635

Query: 772 PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPG 831
            G  G PG  G PG +                 LP ++              +G  G PG
Sbjct: 636 KGKDGLPGQQGLPGSK--------------GITLPCIIP-----------GSYGPSGFPG 670

Query: 832 PPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPG---VRGLKGLPGRNGEKGSQGF-GYPG 887
            PG  GP+G RGLPG PG+ G  G  G PG PG   +  L G PG  GEKG  GF G PG
Sbjct: 671 TPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPG 730

Query: 888 EQGPPGPPGPEGPPGI---------SKEGPPGDPGLPGKD------GDHGKPGIQGQPGP 932
           + G PG  G  G PG          ++ G PG+ GL G        GD G PG++G  G 
Sbjct: 731 KDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGK 790

Query: 933 PGICDP 938
           PG+  P
Sbjct: 791 PGLLGP 796



 Score =  263 bits (671), Expect = 8e-70
 Identities = 169/432 (39%), Positives = 206/432 (47%), Gaps = 77/432 (17%)

Query: 420  ACEIPGFNGECLNGPS-DVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKP 478
            A  +PG  G+  NG + ++  +P P    PG+ G +G KG  GL GN G+PG  G+DGK 
Sbjct: 1061 ASGLPGLKGD--NGQTVEISGSPGPK-GQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKV 1117

Query: 479  GYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGD---------RGLPGFPGLHGM- 528
            G  G  G PG PG PG+ G RG PG  G  G  G  G          +G PGFPGLHG+ 
Sbjct: 1118 GVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLN 1177

Query: 529  -------------------PGSKGEMGAKGDKGSPGFY----GKKGAKGEKGNAGFPGLP 565
                               PG  G  G KG+KG PG      GK G +G+KG+ GFPGL 
Sbjct: 1178 GLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQ 1237

Query: 566  GPAG---------------EPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
            GPAG               +PG  G+ GL G  G  G AG PG PG    +G+ G PGFP
Sbjct: 1238 GPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFP 1297

Query: 611  GNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPG-- 668
            G  G  G KG+ G PG  G    PG  GL G  G PG  GTPG  G  G+PG  GM G  
Sbjct: 1298 GIPGPKGPKGDQGIPGFSG---LPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKA 1354

Query: 669  ----ASGLKGEPGAT----------------GSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
                +SGL+G+PG T                G  G PG  G PG QG  G +G++G  GI
Sbjct: 1355 GPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGI 1414

Query: 709  QGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQ 768
             G+ G +G  G PG  G  G  G +G  G +G PG +G  G  G  G    +G    K  
Sbjct: 1415 PGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHS 1474

Query: 769  PGDPGPQGPPGL 780
              +  P  P G+
Sbjct: 1475 QSEQVPPCPIGM 1486



 Score =  202 bits (515), Expect = 9e-52
 Identities = 136/355 (38%), Positives = 172/355 (48%), Gaps = 36/355 (10%)

Query: 609 FPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPG 668
           FP  +G  G+ G IG  G  G +G  G  GL G  G  G PG  G  G KG+ G  G+PG
Sbjct: 43  FP-EKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPG 101

Query: 669 ASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQG 728
             G+ G PG    PG+PG  G PG+ G  G +G  G  G  G  G  G  G+PGQ+G +G
Sbjct: 102 FLGINGIPG---HPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKG 158

Query: 729 HH-----GAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGK 783
                    KG +G+ G PG+ G  G +G  G  G +GPAGP G  G PGP GP G DG 
Sbjct: 159 DPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGN 218

Query: 784 PGREFSEQFIRQVCTDV-IRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPR 842
            G  F  +  + V  DV +         +G +        + GS G PGP G  G  GP 
Sbjct: 219 MGLGFQGE--KGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPP 276

Query: 843 GLPGL--------PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-------GYPG 887
           G PGL         G  G+PGL G  G  G  G++G PG+ G+KG+ GF       G  G
Sbjct: 277 GFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEG 336

Query: 888 EQGPPGPPGPE---GPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
           ++G  G PGP+      G    G PGDPG+       G PG++G  G  G+  PS
Sbjct: 337 QKGDIGLPGPDVFIDIDGAVISGNPGDPGV------PGLPGLKGDEGIQGLRGPS 385


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score =  380 bits (975), Expect = e-105
 Identities = 251/608 (41%), Positives = 289/608 (47%), Gaps = 103/608 (16%)

Query: 434  PSDVGSTPAPCICP--------PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAG 485
            P   G T  PCI P        PG PG  GPKG  GLPG PG PG  G  G+PG  G+  
Sbjct: 647  PGSKGIT-LPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVH 705

Query: 486  TPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPG--------SKGEMGA 537
             P +PG PG +G +GLPG+ G PG+DG  G  G PG PG  G  G        + GE G 
Sbjct: 706  LPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGL 765

Query: 538  KGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQ 597
            +G  G  GF G  G  G KG  G PGL GP GE G  G  G +G PG  G +G  G  G+
Sbjct: 766  QGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGK 825

Query: 598  DGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGM------PGLMGSNGSPGQPGT 651
             G  G PG PG  G+ G  G +G+ GPPG   KKG PG+      PGL+G  GSPG PG 
Sbjct: 826  SGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGV 885

Query: 652  PG------SKGSKGE---------PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGK 696
             G       KG KG          PG+ G+PG  GLKG PG+TG  G  G  G PG +G 
Sbjct: 886  AGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD 945

Query: 697  ---------------------KGDKGNQGEKGI------QGQKGENGRQGIPGQQGIQGH 729
                                 KGDKG+QG  G       +G KGE GR G PG  G  G 
Sbjct: 946  RGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGL 1005

Query: 730  HGA-KGERGEKGEPG---VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPG 785
             G  KG  G+ G PG   +RG  G KG SG+ G  G  G  G  G  G  G PG  G PG
Sbjct: 1006 PGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPG 1065

Query: 786  REFSEQFIRQVCTDVIRAQLP-------VLLQSGRIRNC--------DHCLSQHGSPGIP 830
             +       ++         P          + G I N         D  +   G  G+P
Sbjct: 1066 LKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLP 1125

Query: 831  GPPGPIGPEGPRGLPGLPGRDG---------VPGLVG---VPGRPGVRGLKGLPGRNGEK 878
            G PG  G  G RG PGLPG  G          PGL+G    PG PG+ GL GLPG  G  
Sbjct: 1126 GAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTH 1185

Query: 879  GSQG---FGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQ---PGP 932
            G+ G    G PG  G PGP G +G PGI   G PG PGL G+ GD G PG+QG    PG 
Sbjct: 1186 GTPGPSITGVPGPAGLPGPKGEKGYPGIG-IGAPGKPGLRGQKGDRGFPGLQGPAGLPGA 1244

Query: 933  PGICDPSL 940
            PGI  PSL
Sbjct: 1245 PGISLPSL 1252



 Score =  375 bits (963), Expect = e-103
 Identities = 227/526 (43%), Positives = 265/526 (50%), Gaps = 71/526 (13%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEP 508
            GKPGL GPKG+ G PG PG  GQPG  G  G  GI G  G+PG+PG  G  G PG KG  
Sbjct: 788  GKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTR 847

Query: 509  GRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPG------FYGKKGAKGEKGNAGFP 562
            G+ G  G     G PGL G+PG+ G +G KG  GSPG        G KG KG  G  GFP
Sbjct: 848  GKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFP 907

Query: 563  GLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNR--------- 613
            G+PG  G PG  G  G+ GS G  G +G  G PG+ G RG PG  G P  R         
Sbjct: 908  GIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLK 967

Query: 614  ---------------GLMGQKGEIGPPGQQGKKGAPGMPGLM-GSNGSPGQPGTPGSKGS 657
                           G  G KGE G PG  G  GAPG+PG++ G +G PG PG  G +G 
Sbjct: 968  GDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL 1027

Query: 658  ---KGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGN-QGEKGIQGQKG 713
               KG  GI G PG  G  G  G  GSPG PG  GLPG++G  G      G  G +GQ G
Sbjct: 1028 PGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPG 1087

Query: 714  ENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPG 773
            E+G +G  G+ G+ G+ G  G +GE G+ GV G +G  G  G  G+ G  G  G PG  G
Sbjct: 1088 ESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSG 1147

Query: 774  PQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPP 833
             QG  G  G PG    + F             P L               HG  G+PG  
Sbjct: 1148 HQGAIGPLGSPGLIGPKGF----------PGFPGL---------------HGLNGLPGTK 1182

Query: 834  GPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVR-GLKGLPGRNGEKGSQGFGYPGEQGPP 892
            G  G  GP  + G+PG  G+PG  G  G PG+  G  G PG  G+KG +GF  PG QGP 
Sbjct: 1183 GTHGTPGP-SITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGF--PGLQGPA 1239

Query: 893  GPPGPEGPPGISKE----GPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
            G PG    PGIS      G PGDPG PG DG+ G+PG  G PGPPG
Sbjct: 1240 GLPGA---PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPG 1282



 Score =  365 bits (937), Expect = e-100
 Identities = 235/581 (40%), Positives = 282/581 (48%), Gaps = 79/581 (13%)

Query: 423  IPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQG 482
            +PG  G+   G   +   P      PG PGL G  G PGLPG  G PG  G+DG PG QG
Sbjct: 588  LPGDGGQGFPGEKGLPGLPGEK-GHPGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQG 645

Query: 483  IAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGA----- 537
            + G+ G+     I G+ G  G+ G PG  G KG RGLPG PG  G  GSKGE G+     
Sbjct: 646  LPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVH 705

Query: 538  ----------KGDKGSPGFYGKKGAKGEKGNAGFPGLPGPA-----------GEPGRHGK 576
                      +G+KG PGF G  G  G  G  G PGLPG             G PG  G 
Sbjct: 706  LPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGL 765

Query: 577  DGLMGSPGFKGEAGSP------GAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGK 630
             GL G  GF G++G P      G PG  G +GE G PG PG  G  G  G  GP G +GK
Sbjct: 766  QGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGK 825

Query: 631  KGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGAT---GSPGEPGY 687
             G PG PG  G +G PG+ GT G KG  G    +G+PG  GL G PG     GSPG PG 
Sbjct: 826  SGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGV 885

Query: 688  MGLPGIQGKKGDKGN------QGEKGIQGQKGENGRQGIP---GQQGIQGHHGAKGERGE 738
             GLP + G KG+KG+       G  G+ G  G  G +GIP   G+ G  G  G  GE+G+
Sbjct: 886  AGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD 945

Query: 739  KGEPG---------------VRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGK 783
            +G PG               ++G  GS+G +G +G  GP G KG+ G PGP G PG  G 
Sbjct: 946  RGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGL 1005

Query: 784  PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRG 843
            PG          +   V     P       IR         G  G PG PG  G +G RG
Sbjct: 1006 PG----------IIKGVSGKPGPPGFMG--IRGLPGLKGSSGITGFPGMPGESGSQGIRG 1053

Query: 844  LPGLPGRDGVPGLVGVPGR----PGVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPE 898
             PGLPG  G+PGL G  G+     G  G KG PG +G KG++G  G  G  G PG  G +
Sbjct: 1054 SPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGED 1113

Query: 899  GPPGISKE-GPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938
            G  G+S + G PG PG PG  G  G+PG+ G  G  G   P
Sbjct: 1114 GKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGP 1154



 Score =  361 bits (926), Expect = 2e-99
 Identities = 237/583 (40%), Positives = 280/583 (48%), Gaps = 103/583 (17%)

Query: 423 IPGFNGECLNGPSDVGSTPAP--------CICPPGKPGLQGPKGDPGLPGNPGYPGQPGQ 474
           +PGF G  +NG       P P        C    G  G  GP G PGL G PG PGQ G 
Sbjct: 98  VPGFLG--INGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGS 155

Query: 475 DGKP-----GYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMP 529
            G P      ++G+ G PG+PG  GI G +G PG+ G  G  G  G +G PG PG  G  
Sbjct: 156 KGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPD 215

Query: 530 GS-----KGEMGAKGDKGSPGFYGKKGAKGEKGNAGFP-GLPGPAGEPGRHGKDGLMGSP 583
           G+     +GE G KGD G PG  G   + GE    GFP G  G  GEPG  G  G+ G P
Sbjct: 216 GNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPP 275

Query: 584 GFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG-- 641
           GF G     G  G+ G +GE GIPG PG RG MG +G  GPPGQQGKKG  G PGL G  
Sbjct: 276 GFPG----LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQ 331

Query: 642 ------------------------SNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPG 677
                                    +G+PG PG PG  G KG+ GIQG+ G SG+ G P 
Sbjct: 332 GIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPA 391

Query: 678 ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGE-- 735
            +G PG  G  G PG+   KGD+GN G   I G  G  GR G+PG  G  G    + E  
Sbjct: 392 LSGVPGALGPQGFPGL---KGDQGNPGRTTI-GAAGLPGRDGLPGPPGPPGPPSPEFETE 447

Query: 736 ---RGEKGEPGVRGAIGSKGESGVDGLMGPAG---------PKGQPGDPGPQGPPGLDGK 783
                E G PG+RG  G KG  G+ G+ G +G           G PG+PGP GP GL G 
Sbjct: 448 TLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGL 507

Query: 784 PGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPR- 842
           PG                      L  +   R         G+PG+ GP GP GP+G + 
Sbjct: 508 PG----------------------LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKG 545

Query: 843 --------GLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGP 894
                   G+PG  G  G  G  GV G PG  G+ GLPG  G  G  G G+PGE+G PG 
Sbjct: 546 EPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGL 605

Query: 895 PGPE---GPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
           PG +   GPPG+   G PG PG  G  GD GK G+ GQ G PG
Sbjct: 606 PGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPG 648



 Score =  356 bits (914), Expect = 5e-98
 Identities = 216/509 (42%), Positives = 266/509 (52%), Gaps = 52/509 (10%)

Query: 449  GKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGY-QGIAGTPGVPGS------PGIQGARGL 501
            G  G  GP+GD G  G PG PG PG  G PG  +G++G PG PG       PG++G+ G+
Sbjct: 977  GSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGI 1036

Query: 502  PGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD-KGSPGFYGKKGAKGEKGNAG 560
             G+ G PG  G +G RG PG PG  G+PG KG+ G   +  GSPG  G+ G  G KG  G
Sbjct: 1037 TGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKG 1096

Query: 561  FPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKG 620
              GL G  G PG  G+DG +G  G  G  G+PG PG  G RGEPG+PG  G++G +G   
Sbjct: 1097 RDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGP-- 1154

Query: 621  EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSK--GEPGIQGMPGASGLKGEPG- 677
             +G PG  G KG PG PGL G NG PG  GT G+ G    G PG  G+PG  G KG PG 
Sbjct: 1155 -LGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGI 1213

Query: 678  ATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGEN------GRQGIPGQQGIQGHHG 731
              G+PG+PG   L G +G +G  G QG  G+ G  G +      G+ G PG+ G+ G  G
Sbjct: 1214 GIGAPGKPG---LRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG 1270

Query: 732  AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQ 791
              G  G  G PG     G  G+ G  G+ GP GPKG  G PG  G PG  G  G      
Sbjct: 1271 RPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKG------ 1324

Query: 792  FIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRD 851
                     +R +   +   G++          G PG PG  G  GP G  GL G PG+ 
Sbjct: 1325 ---------MRGEPGFMGTPGKV-------GPPGDPGFPGMKGKAGPRGSSGLQGDPGQT 1368

Query: 852  GVPGLVGVPGRP-GVRGLKGLPGRNGEKGSQG-FGYPGEQGPPGPPGPEGPPGISKEGPP 909
                 V VP  P G+ G+ G+PG  G+ G+QG  G  G +G PG PG +GP G+   GPP
Sbjct: 1369 PTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLP--GPP 1426

Query: 910  G---DPGLPGKDGDHGKPGIQGQPGPPGI 935
            G   DPGLPG  G  G  G  GQ GP G+
Sbjct: 1427 GALGDPGLPGLQGPPGFEGAPGQQGPFGM 1455



 Score =  355 bits (912), Expect = 9e-98
 Identities = 236/597 (39%), Positives = 273/597 (45%), Gaps = 129/597 (21%)

Query: 448  PGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
            PG PGL G KG PG PG  G P   G  G+ G  G  G PG+PG PGI G RGL G  G 
Sbjct: 868  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 927

Query: 508  PGRDGDKGDRGLPGFPGLHGMPGS---------------KGEMGAKGDKGSPGFYGKKGA 552
             G+ G  G  G PG  G  G PG                KG+ G++G  GS GF G +G 
Sbjct: 928  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGD 987

Query: 553  KGEKGNAGFPGLPGP----------AGEPGRHGKDGLMGSPGFKGEAGS---PGAPGQDG 599
            KGE G  G PGLPG           +G+PG  G  G+ G PG KG +G    PG PG+ G
Sbjct: 988  KGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESG 1047

Query: 600  TRGEPGIPGFPGNRGLMGQKGEIGP-------------PGQQGKKGAPGMPGLMGSNGSP 646
            ++G  G PG PG  GL G KG+ G              PG+ G KG  G  GL+G+ G P
Sbjct: 1048 SQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFP 1107

Query: 647  GQPGTPGSKGSKGE---PGIQGMPGASGLKGEPGATGSPGEPGY---MGLPGIQGKKGDK 700
            G  G  G  G  G+   PG  G PG +G++GEPG  GS G  G    +G PG+ G KG  
Sbjct: 1108 GNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFP 1167

Query: 701  GNQGEKGIQGQKGENGRQGIPGQQ--GIQGHHGAKGERGEKGEPGVR-------GAIGSK 751
            G  G  G+ G  G  G  G PG    G+ G  G  G +GEKG PG+        G  G K
Sbjct: 1168 GFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQK 1227

Query: 752  GESGVDGLMGPAGPKGQPG---------DPGPQGPPGLDGKPGREFSEQFIRQVCTDVIR 802
            G+ G  GL GPAG  G PG          PG  G PGLDG+ GR                
Sbjct: 1228 GDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGP------------- 1274

Query: 803  AQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGL--------------- 847
            A  P     G   N        G PG PG PGP GP+G +G+PG                
Sbjct: 1275 AGPPG--PPGPSSN----QGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGE 1328

Query: 848  PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG------------------------- 882
            PG  G PG VG PG PG  G+KG  G  G  G QG                         
Sbjct: 1329 PGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDG 1388

Query: 883  ----FGYPGEQGPPGPPGPEGPPGI-SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                 G PG QGP G  G +G PGI  K+GP G PG PG  GD G PG+QG PG  G
Sbjct: 1389 IPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEG 1445



 Score =  350 bits (898), Expect = 4e-96
 Identities = 231/577 (40%), Positives = 265/577 (45%), Gaps = 104/577 (18%)

Query: 423  IPGFNGECLNGPSDVGSTPAPC-----ICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGK 477
            +PG  G    G    G    P      + P G  G +G KG+P L    G PG  G  G 
Sbjct: 507  LPGLKGA--RGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGS 564

Query: 478  PGYQGIAGTPGVPGSPGIQGARGL--------PGYKGEPGRDGDKGDRGLPGFPGLHGMP 529
             G++G+ G PG  G PG+ G  GL        PG KG PG  G+KG  G PG PG +G+P
Sbjct: 565  QGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPG-NGLP 623

Query: 530  GSKGEMGAKGDKGSPGFYGKKGAKGEKGNA---------------GFPGLPGPAGEPGRH 574
            G  G  G  GDKG  G  G++G  G KG                 G PG PGP G  G  
Sbjct: 624  GLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLP 683

Query: 575  GKDGLMGSPGFKGEAGSPG------APGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQ 628
            G  G  GS G KGE GSPG       PG  G RGE G+PGFPG  G  G  G IG PG  
Sbjct: 684  GTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLP 743

Query: 629  GKKGAPGMPGLMGS-NGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGY 687
            G KGA G   + G+ NG+PG+ G  G  G KG  G  G+PG  G+ G+PG  G  GE G 
Sbjct: 744  GSKGATG--DIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGS 801

Query: 688  MGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGA 747
             G PG  G+ G  G+ G  GI   KG++G  G PG  GI GH G KG RG+KG PG    
Sbjct: 802  PGTPGQVGQPGTPGSSGPYGI---KGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVK 858

Query: 748  IGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPV 807
             G  G  G+ G  G  G KG PG PG  G P L G  G + S  F+              
Sbjct: 859  KGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFV-------------- 904

Query: 808  LLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRG 867
                             G PGIPG PG  G  G +G+PG  G+ G  G  G PG  G RG
Sbjct: 905  -----------------GFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRG 947

Query: 868  ------------------LKGLPGRNGEKGSQGF----GYPGEQGPPGPPGPEGPPGI-- 903
                              LKG  G  G  GS GF    G  GE G PGPPG  G PG+  
Sbjct: 948  NPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPG 1007

Query: 904  ------SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPG 934
                   K GPPG  G+ G  G  G  GI G PG PG
Sbjct: 1008 IIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPG 1044



 Score =  339 bits (869), Expect = 8e-93
 Identities = 229/602 (38%), Positives = 277/602 (46%), Gaps = 112/602 (18%)

Query: 449 GKP-GLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGE 507
           GKP G Q   G        G  G+PG  G  G  G  G  G  G  G++G RG PG  G 
Sbjct: 27  GKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGP 86

Query: 508 PGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGP 567
            G  GDKG  G+PGF G++G+PG  G+ G +G  G  G  G +GA G  G  G+PGL GP
Sbjct: 87  YGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGP 146

Query: 568 AGEPGRHGKDG--LMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPP 625
            G PG+ G  G  ++    FKG  G PG PG DG  G  G PGFPG  G  G  G  GPP
Sbjct: 147 PGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP 206

Query: 626 GQ--------------QGKKGAPGMPGLMGSNGSPGQPG-------TPGSKGSKGEPGIQ 664
           G               QG+KG  G  GL G  G P   G         G KGSKGEPG +
Sbjct: 207 GPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPK 266

Query: 665 GMPGASGLKGEP--GATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPG 722
           G PG SG  G P  G TG  GE G  G+PG+ G +G  G++G +G  GQ+G+ G  G PG
Sbjct: 267 GFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPG 326

Query: 723 QQGIQGHHGAKGE-----------------RGEKGEPGVRGAIGSKGESGVDGLMGPA-- 763
             G QG  G KG+                  G  G+PGV G  G KG+ G+ GL GP+  
Sbjct: 327 LNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGV 386

Query: 764 -------------GPKGQPGDPGPQ--------------------GPPGLDGKPGREFSE 790
                        GP+G PG  G Q                    GPPG  G P  EF  
Sbjct: 387 PGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFET 446

Query: 791 QFI--RQVCTDVIRAQ--------LPVLLQSGRIRNCDHCLSQHGSPGIPGPPGP----- 835
           + +  ++     +R +        L  +        CD  +   G PG PGPPGP     
Sbjct: 447 ETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIG 506

Query: 836 ----IGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRG---------LKGLPGRNGEKGSQG 882
                G  G RG  G  G  G PGLVG  G  G +G         ++G+PG  G+ GSQG
Sbjct: 507 LPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQG 566

Query: 883 F----GYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGP--PGIC 936
           F    G PG+ G PG PG  G PG   +G PG+ GLPG  G+ G PG  G PG   PG+ 
Sbjct: 567 FRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLP 626

Query: 937 DP 938
            P
Sbjct: 627 GP 628



 Score =  336 bits (861), Expect = 7e-92
 Identities = 229/606 (37%), Positives = 280/606 (46%), Gaps = 123/606 (20%)

Query: 425 GFNGECLNGPSDVGSTPAPCICPP---------------GKPGLQGPKGDPGLPGNPGYP 469
           GF GE      DVG  P P   PP               G  G  GPKG PG+ G PG+P
Sbjct: 221 GFQGE-KGVKGDVG-LPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFP 278

Query: 470 GQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMP 529
           G     G  G +G  G  G+PG PG +G  G  G +G PG+ G KG  G PG  G  G+ 
Sbjct: 279 GL----GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIE 334

Query: 530 GSKGEMGAKGD-----------KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDG 578
           G KG++G  G             G+PG  G  G  G KG+ G  GL GP+G PG     G
Sbjct: 335 GQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSG 394

Query: 579 LMGS------PGFKGEAGSPGA--------PGQDGTRGEPGIPG---------------- 608
           + G+      PG KG+ G+PG         PG+DG  G PG PG                
Sbjct: 395 VPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKES 454

Query: 609 -FPGNRGLMGQKGEIGPPGQQGKKG------------APGMPGLMGSNGSPGQPGTPGSK 655
            FPG RG  G KG +G  G +G  G             PG PG  G  G  G PG  G++
Sbjct: 455 GFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGAR 514

Query: 656 GSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGEN 715
           G +G  G QG  GA GL G  G +G  G+ G   L  IQG  GD+G+ G +G +G  GE 
Sbjct: 515 GDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEP 574

Query: 716 GRQGIPGQQGIQG--HHGAKGERGEKGEPGVRGAIGSKGESGV--DGLMGPAGPKGQPGD 771
           G+ G+PG  G+ G    G +G  GEKG PG+ G  G  G  G+  +GL G  GP+G PGD
Sbjct: 575 GKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGD 634

Query: 772 PGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPG 831
            G  G PG  G PG +                 LP ++              +G  G PG
Sbjct: 635 KGKDGLPGQQGLPGSK--------------GITLPCIIP-----------GSYGPSGFPG 669

Query: 832 PPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPG---VRGLKGLPGRNGEKGSQGF-GYPG 887
            PG  GP+G RGLPG PG+ G  G  G PG PG   +  L G PG  GEKG  GF G PG
Sbjct: 670 TPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPG 729

Query: 888 EQGPPGPPGPEGPPGI---------SKEGPPGDPGLPGKD------GDHGKPGIQGQPGP 932
           + G PG  G  G PG          ++ G PG+ GL G        GD G PG++G  G 
Sbjct: 730 KDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGK 789

Query: 933 PGICDP 938
           PG+  P
Sbjct: 790 PGLLGP 795



 Score =  263 bits (671), Expect = 8e-70
 Identities = 169/432 (39%), Positives = 206/432 (47%), Gaps = 77/432 (17%)

Query: 420  ACEIPGFNGECLNGPS-DVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKP 478
            A  +PG  G+  NG + ++  +P P    PG+ G +G KG  GL GN G+PG  G+DGK 
Sbjct: 1060 ASGLPGLKGD--NGQTVEISGSPGPK-GQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKV 1116

Query: 479  GYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGD---------RGLPGFPGLHGM- 528
            G  G  G PG PG PG+ G RG PG  G  G  G  G          +G PGFPGLHG+ 
Sbjct: 1117 GVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLN 1176

Query: 529  -------------------PGSKGEMGAKGDKGSPGFY----GKKGAKGEKGNAGFPGLP 565
                               PG  G  G KG+KG PG      GK G +G+KG+ GFPGL 
Sbjct: 1177 GLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQ 1236

Query: 566  GPAG---------------EPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610
            GPAG               +PG  G+ GL G  G  G AG PG PG    +G+ G PGFP
Sbjct: 1237 GPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFP 1296

Query: 611  GNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPG-- 668
            G  G  G KG+ G PG  G    PG  GL G  G PG  GTPG  G  G+PG  GM G  
Sbjct: 1297 GIPGPKGPKGDQGIPGFSG---LPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKA 1353

Query: 669  ----ASGLKGEPGAT----------------GSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708
                +SGL+G+PG T                G  G PG  G PG QG  G +G++G  GI
Sbjct: 1354 GPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGI 1413

Query: 709  QGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQ 768
             G+ G +G  G PG  G  G  G +G  G +G PG +G  G  G  G    +G    K  
Sbjct: 1414 PGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHS 1473

Query: 769  PGDPGPQGPPGL 780
              +  P  P G+
Sbjct: 1474 QSEQVPPCPIGM 1485



 Score =  202 bits (515), Expect = 9e-52
 Identities = 136/355 (38%), Positives = 172/355 (48%), Gaps = 36/355 (10%)

Query: 609 FPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPG 668
           FP  +G  G+ G IG  G  G +G  G  GL G  G  G PG  G  G KG+ G  G+PG
Sbjct: 42  FP-EKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPG 100

Query: 669 ASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQG 728
             G+ G PG    PG+PG  G PG+ G  G +G  G  G  G  G  G  G+PGQ+G +G
Sbjct: 101 FLGINGIPG---HPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKG 157

Query: 729 HH-----GAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGK 783
                    KG +G+ G PG+ G  G +G  G  G +GPAGP G  G PGP GP G DG 
Sbjct: 158 DPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGN 217

Query: 784 PGREFSEQFIRQVCTDV-IRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPR 842
            G  F  +  + V  DV +         +G +        + GS G PGP G  G  GP 
Sbjct: 218 MGLGFQGE--KGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPP 275

Query: 843 GLPGL--------PGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-------GYPG 887
           G PGL         G  G+PGL G  G  G  G++G PG+ G+KG+ GF       G  G
Sbjct: 276 GFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEG 335

Query: 888 EQGPPGPPGPE---GPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939
           ++G  G PGP+      G    G PGDPG+       G PG++G  G  G+  PS
Sbjct: 336 QKGDIGLPGPDVFIDIDGAVISGNPGDPGV------PGLPGLKGDEGIQGLRGPS 384


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
            sapiens]
          Length = 1899

 Score =  379 bits (974), Expect = e-105
 Identities = 263/766 (34%), Positives = 362/766 (47%), Gaps = 96/766 (12%)

Query: 28   RSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFD-IGPKFIQVGVVQYSDYPV 86
            R  C+ A  D+VF+ D S+S+G +NF  V K++ N    FD I P  IQV  VQYSD   
Sbjct: 1150 RDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVK 1209

Query: 87   LEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSS---RFLTKIAVVLT 143
             E  L +Y+       A+++I Y GGNT+TGKA+ F  + +    S   + + K+ VV+T
Sbjct: 1210 SEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVT 1269

Query: 144  DGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKI 203
            DG+SQD+VK AA   + S  ++F +GV ++ +  EL  IA+KPS  +VF V+D+ +  KI
Sbjct: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGV-ADVDYNELANIASKPSERHVFIVDDFESFEKI 1328

Query: 204  REVMKQKLCEE--SVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQL------SPKKIK 255
             + +   +CE   S CP  I +      GF +L   ++ +K    +Q       S     
Sbjct: 1329 EDNLITFVCETATSSCPL-IYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYS 1387

Query: 256  GYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWD---LWRILTIDGRPQIAVT 312
             Y +     +++ T+++ P GLPPSY  +   R   +   D   +W+I   D +PQ+ V 
Sbjct: 1388 AYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVI 1447

Query: 313  LNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIEN 372
             +   K L F         Q VTF   +VKTLF   +H++ ++VT + V +YID  +I  
Sbjct: 1448 ADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIE 1507

Query: 373  KPLHPVLGILINGQTQIGKY-SGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGECL 431
            K +     I  +G   +GK   G+ ++  F +Q   I C P   +R+  C+IP    E  
Sbjct: 1508 KDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDE-- 1565

Query: 432  NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG 491
                   + P  C C          +   G PG PG  G PG  G  G +GI+G  G PG
Sbjct: 1566 ---GKCPAFPNSCTCT---------QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG 1613

Query: 492  SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKG 551
                +G  G PG +G PG  G  G            +PG +G  G KGD G PG  G+ G
Sbjct: 1614 P---RGDIGPPGPQGPPGPQGPNG----------LSIPGEQGRQGMKGDAGEPGLPGRTG 1660

Query: 552  AKGEKGNAGFPGLPGPAGEPGRHG---KDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPG 608
              G       PG PGP G PG  G   KDG MG  G  G  GSPG+PG  G  G+PG PG
Sbjct: 1661 TPG------LPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG 1714

Query: 609  F---PGNRGLMGQKGEIGPPGQQG------------------------------------ 629
                PG  GL G+KG+ G    Q                                     
Sbjct: 1715 DHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 1774

Query: 630  -KKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYM 688
             + G PG PG  GS G+ G+PG  G  G  G PG+QG PG  GL GE G  G+ G  G  
Sbjct: 1775 NQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPR 1833

Query: 689  GLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKG 734
            GLPG  G +G+    G  G  G +G  G  G PG  GI+G  G  G
Sbjct: 1834 GLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878



 Score =  240 bits (613), Expect = 4e-63
 Identities = 145/354 (40%), Positives = 174/354 (49%), Gaps = 38/354 (10%)

Query: 601  RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660
            R E   P FP +      +  +GPPG  G  G PG  G  G  G  G  G PG +G  G 
Sbjct: 1563 RDEGKCPAFPNS--CTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP 1620

Query: 661  PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI 720
            PG QG PG  G             P  + +PG QG++G KG+ GE G+ G+    G  G+
Sbjct: 1621 PGPQGPPGPQG-------------PNGLSIPGEQGRQGMKGDAGEPGLPGR---TGTPGL 1664

Query: 721  PGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGL 780
            PG  G  G  G +G  G+ G  G RG  G  G  G  G+ GP+G  G+PGD G  GP GL
Sbjct: 1665 PGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 1724

Query: 781  DGKPG-------REFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPP 833
             G+ G       +       RQVC  +I  Q+    Q       D+  S    PG PGPP
Sbjct: 1725 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-QSSRNQPGPPGPP 1783

Query: 834  GPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPG 893
            GP G  G RG PG  GR G PG  G+ G PG RGL   PG  GE+G+      G  GP G
Sbjct: 1784 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGL---PGEKGERGT------GSSGPRG 1834

Query: 894  PPGPEGPPGISKEGPPGDPGLPGKDGDHGKPG---IQGQPGPPGICDPSLCFSV 944
             PGP GP G S+ GPPG  G  G  G  G+PG   I+G PGPPG CD S C S+
Sbjct: 1835 LPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASI 1888



 Score =  196 bits (498), Expect = 9e-50
 Identities = 135/363 (37%), Positives = 157/363 (43%), Gaps = 73/363 (20%)

Query: 558  NAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMG 617
            + G PG PGPAG PG  G          +GE G  GA G  G RG+ G PG  G  G  G
Sbjct: 1581 SVGPPGPPGPAGGPGAKGP---------RGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 1631

Query: 618  QKGEI--GPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGE 675
              G    G  G+QG KG  G PGL G  G+PG PG PG  G  G+ G  G  GA G +G 
Sbjct: 1632 PNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP 1691

Query: 676  PGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENG----------------RQG 719
            PG  GSPG PG  G  G  GK GD G  G  G++G+KG+ G                 Q 
Sbjct: 1692 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 1751

Query: 720  IPGQ---------QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770
            I GQ         Q    +  ++ + G  G PG  G+ G++GE       GP G  G PG
Sbjct: 1752 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------GPGGRPGFPG 1805

Query: 771  DPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIP 830
             PG QGPPG  G PG +                              +      G  G+P
Sbjct: 1806 TPGMQGPPGERGLPGEK-----------------------------GERGTGSSGPRGLP 1836

Query: 831  GPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQG 890
            GPPGP G E   G PG  G  G PG  G PG  G+RG  G PG           Y G QG
Sbjct: 1837 GPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG-QG 1894

Query: 891  PPG 893
             PG
Sbjct: 1895 YPG 1897



 Score =  130 bits (328), Expect = 4e-30
 Identities = 80/229 (34%), Positives = 126/229 (55%), Gaps = 15/229 (6%)

Query: 15  LLQNSVLAEDGEVRSSCRT-APTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKF 73
           LL +S+ AE  E    C T A  D+V ++DGS+S+G  NF  V+ ++  I + FDIGPK 
Sbjct: 16  LLLSSIEAEGME----CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKR 71

Query: 74  IQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSR 133
           +Q+ + QYS  P  E  L ++   + L  AV ++ Y GGNT TG A+ F     F   + 
Sbjct: 72  VQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAG 131

Query: 134 F---LTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTY 190
                 KI V++TDGKSQDDV+  ++  +D  + LFAIG+    ++ EL+ IA  P  T+
Sbjct: 132 MRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGI-KNADEVELKMIATDPDDTH 190

Query: 191 VFYVEDYIAISKIREVMKQKLCE------ESVCPTRIPVAARDERGFDI 233
            + V D+ ++S+I + +   LC       +   P+ + ++ R  R F +
Sbjct: 191 AYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRV 239



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 40/98 (40%), Positives = 50/98 (51%), Gaps = 22/98 (22%)

Query: 447  PPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGI-----------AGTPGVPGSPGI 495
            PPG PG  G +G+PG  G PG+PG PG  G PG +G+           +G  G+PG PG 
Sbjct: 1782 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGP 1841

Query: 496  QG-----------ARGLPGYKGEPGRDGDKGDRGLPGF 522
            QG           +RG PG  G PG  G +G  G PG+
Sbjct: 1842 QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 1879



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 29/80 (36%), Positives = 33/80 (41%), Gaps = 8/80 (10%)

Query: 423  IPGFNGECLNGPSDVGSTPAPC----ICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKP 478
            +PG  GE   G S     P P         G PG  G +G PG PG PG  G  G  G P
Sbjct: 1818 LPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 1877

Query: 479  GYQGIAGTPGVP----GSPG 494
            GY   +    +P    G PG
Sbjct: 1878 GYCDSSQCASIPYNGQGYPG 1897


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.142    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,184,651
Number of Sequences: 37866
Number of extensions: 3939763
Number of successful extensions: 165890
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 337
Number of HSP's successfully gapped in prelim test: 840
Number of HSP's that attempted gapping in prelim test: 15385
Number of HSP's gapped (non-prelim): 16270
length of query: 957
length of database: 18,247,518
effective HSP length: 112
effective length of query: 845
effective length of database: 14,006,526
effective search space: 11835514470
effective search space used: 11835514470
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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