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Search of human proteins with 11321593
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11321593 insulin-like growth factor binding protein 6 [Homo
sapiens]
(240 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11321593 insulin-like growth factor binding protein 6 [Homo s... 513 e-146
gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 150 1e-36
gi|62243068 insulin-like growth factor binding protein 3 isoform... 134 7e-32
gi|62243248 insulin-like growth factor binding protein 3 isoform... 132 3e-31
gi|62243290 insulin-like growth factor binding protein 4 precurs... 124 9e-29
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 115 4e-26
gi|4504615 insulin-like growth factor binding protein 1 precurso... 95 5e-20
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 55 7e-08
gi|93141003 testican 3 isoform 1 [Homo sapiens] 52 5e-07
gi|93141001 testican 3 isoform 2 [Homo sapiens] 52 5e-07
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 52 6e-07
gi|55770862 thyroglobulin [Homo sapiens] 50 2e-06
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 49 5e-06
gi|144953895 nidogen 2 precursor [Homo sapiens] 45 4e-05
gi|115298674 nidogen 1 precursor [Homo sapiens] 44 1e-04
gi|56090548 insulin-like growth factor binding protein-like 1 [H... 43 2e-04
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 40 0.001
gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 39 0.004
gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 39 0.004
gi|17511255 poly(A) binding protein interacting protein 1 isofor... 36 0.034
gi|122891874 keratin associated protein 5-5 [Homo sapiens] 35 0.044
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 35 0.058
gi|166795236 tumor-associated calcium signal transducer 2 precur... 35 0.076
gi|145199237 transcription elongation factor B polypeptide 3 bin... 35 0.076
gi|218505670 epithelial cell adhesion molecule precursor [Homo s... 34 0.099
gi|51972220 keratin associated protein 5-2 [Homo sapiens] 34 0.13
gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens] 33 0.17
gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens] 33 0.17
gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens] 33 0.29
gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens] 33 0.29
>gi|11321593 insulin-like growth factor binding protein 6 [Homo
sapiens]
Length = 240
Score = 513 bits (1322), Expect = e-146
Identities = 240/240 (100%), Positives = 240/240 (100%)
Query: 1 MTPHRLLPPLLLLLALLLAASPGGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEA 60
MTPHRLLPPLLLLLALLLAASPGGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEA
Sbjct: 1 MTPHRLLPPLLLLLALLLAASPGGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEA 60
Query: 61 EGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARAPAVAEENPKES 120
EGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARAPAVAEENPKES
Sbjct: 61 EGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARAPAVAEENPKES 120
Query: 121 KPQAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGVQDTEMGPCRRHLDSVLQQLQTEVYR 180
KPQAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGVQDTEMGPCRRHLDSVLQQLQTEVYR
Sbjct: 121 KPQAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGVQDTEMGPCRRHLDSVLQQLQTEVYR 180
Query: 181 GAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG 240
GAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG
Sbjct: 181 GAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG 240
>gi|10834982 insulin-like growth factor binding protein 5 [Homo
sapiens]
Length = 272
Score = 150 bits (378), Expect = 1e-36
Identities = 92/268 (34%), Positives = 131/268 (48%), Gaps = 40/268 (14%)
Query: 10 LLLLLALLLAASPG-----GALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCL 64
LL + LLLAA G G+ C C + + CP + E P GC C
Sbjct: 3 LLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMT--CA 60
Query: 65 RREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARA--------------- 109
EGQ CGVYT CA GL+C P +D+E PL ALL GRG CL ++
Sbjct: 61 LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE 120
Query: 110 ----PAVAEE--NPKESKP--------QAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGV 155
+AEE +PK +P +A + + Q + G + + P
Sbjct: 121 EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA 180
Query: 156 ----QDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGP 211
Q++E GPCRRH+++ LQ+L+ + +Y+PNCD +GFY+++QC+ S+G++RG
Sbjct: 181 PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI 240
Query: 212 CWCVDRMGKSLPGSPDGNGSSSCPTGSS 239
CWCVD+ G LPG +G C T S
Sbjct: 241 CWCVDKYGMKLPGMEYVDGDFQCHTFDS 268
>gi|62243068 insulin-like growth factor binding protein 3 isoform b
precursor [Homo sapiens]
Length = 291
Score = 134 bits (337), Expect = 7e-32
Identities = 83/248 (33%), Positives = 113/248 (45%), Gaps = 44/248 (17%)
Query: 19 AASPG-GALARCPGCGQGVQAGC-PGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTP 76
A+S G G + RC C A C P V E P GC C EGQ CG+YT
Sbjct: 29 ASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLT--CALSEGQPCGIYTE 86
Query: 77 NCAPGLQCHPPKDDEAPLRALLLGRGRCLPARA------------PAVAEENPKESKPQA 124
C GL+C P D+ PL+ALL GRG C+ A A PA + E A
Sbjct: 87 RCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSA 146
Query: 125 GTARPQDVNRRDQQRNP----------------------------GTSTTPSQPNSAGVQ 156
G+ V+ + +P ST +S +
Sbjct: 147 GSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKR 206
Query: 157 DTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVD 216
+TE GPCRR ++ L L+ + +++PNCD +GFY+K+QCR S+G++RG CWCVD
Sbjct: 207 ETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD 266
Query: 217 RMGKSLPG 224
+ G+ LPG
Sbjct: 267 KYGQPLPG 274
>gi|62243248 insulin-like growth factor binding protein 3 isoform a
precursor [Homo sapiens]
Length = 297
Score = 132 bits (332), Expect = 3e-31
Identities = 82/254 (32%), Positives = 112/254 (44%), Gaps = 50/254 (19%)
Query: 19 AASPG-GALARCPGCGQGVQAGC-PGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTP 76
A+S G G + RC C A C P V E P GC C EGQ CG+YT
Sbjct: 29 ASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLT--CALSEGQPCGIYTE 86
Query: 77 NCAPGLQCHPPKDDEAPLRALLLGRGRCL------------------PARAPAVAEENPK 118
C GL+C P D+ PL+ALL GRG C+ P PA +
Sbjct: 87 RCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGEPPAPGNASES 146
Query: 119 ESKPQAGTARPQDVNRRDQQRNP----------------------------GTSTTPSQP 150
E AG+ V+ + +P ST
Sbjct: 147 EEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNF 206
Query: 151 NSAGVQDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRG 210
+S ++TE GPCRR ++ L L+ + +++PNCD +GFY+K+QCR S+G++RG
Sbjct: 207 SSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRG 266
Query: 211 PCWCVDRMGKSLPG 224
CWCVD+ G+ LPG
Sbjct: 267 FCWCVDKYGQPLPG 280
>gi|62243290 insulin-like growth factor binding protein 4 precursor
[Homo sapiens]
Length = 258
Score = 124 bits (310), Expect = 9e-29
Identities = 89/251 (35%), Positives = 114/251 (45%), Gaps = 29/251 (11%)
Query: 9 PLLLLLALLLAASPGGALA----RCPGCGQGVQAGC--PGGCVEEEDGGSPAEGCAEAEG 62
PL L+ ALLLAA PG +L CP C + A C P GC EE P GC
Sbjct: 3 PLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGC--EELVREPGCGCCAT-- 58
Query: 63 CLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLP-ARAPAVAEENPKESK 121
C G CGVYTP C GL+C+PP+ E PL L+ G+G C+ A A+ E K
Sbjct: 59 CALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDK 118
Query: 122 -----PQAGTARPQDVNRRDQQ------RNPGTSTTPSQPNSAGVQDTE---MGPCRRHL 167
P + +RR Q R+ TS + N A +D G C+ L
Sbjct: 119 DEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSEL 178
Query: 168 DSVLQQLQTEVYRGAQTLY---VPNCDHRGFYRKRQCRSSQGQRRGPCWCVDR-MGKSLP 223
L++L R + LY +PNCD G + +QC + +RG CWCVDR G LP
Sbjct: 179 HRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLP 238
Query: 224 GSPDGNGSSSC 234
G + G C
Sbjct: 239 GGLEPKGELDC 249
>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
[Homo sapiens]
Length = 328
Score = 115 bits (287), Expect = 4e-26
Identities = 93/298 (31%), Positives = 123/298 (41%), Gaps = 75/298 (25%)
Query: 7 LPPLLLLLALLLAASPGGA------LARCPGCGQGVQAGC------PGGCVEEEDGGSPA 54
L PLL LL LLL AS GG L RCP C A C P V GG+
Sbjct: 17 LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76
Query: 55 E--------GCAEAEGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLP 106
GC C R EG+ CGVYTP C GL+C+P E PL+AL++G G C
Sbjct: 77 PCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEK 136
Query: 107 AR------APAVAEENPKESKPQAGTARPQDVNRRDQQRN--PGTSTTPSQPNSAGV--- 155
R +P +N + + G N D N G + +P +G+
Sbjct: 137 RRDAEYGASPEQVADN-GDDHSEGGLVE----NHVDSTMNMLGGGGSAGRKPLKSGMKEL 191
Query: 156 ---------QDTEMG----------------------PCRRHLDSVLQQLQT---EVYRG 181
Q +MG PC++ LD VL+++ T RG
Sbjct: 192 AVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERG 251
Query: 182 ----AQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVD-RMGKSLPGSPDGNGSSSC 234
+L++PNCD G Y +QC+ S +RG CWCV+ GK + G+P G C
Sbjct: 252 PLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPEC 309
>gi|4504615 insulin-like growth factor binding protein 1 precursor
[Homo sapiens]
Length = 259
Score = 95.1 bits (235), Expect = 5e-20
Identities = 72/245 (29%), Positives = 100/245 (40%), Gaps = 24/245 (9%)
Query: 10 LLLLLALLLAASPGGALARCPGCGQGVQAGCP---GGCVEEEDGGSPAEGCAEAEGCLRR 66
L+LLL + GA +C C A CP C E + + GC C
Sbjct: 11 LVLLLLTVQVGVTAGAPWQCAPCSAEKLALCPPVSASCSEV----TRSAGCGCCPMCALP 66
Query: 67 EGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCL---PARAPAVAEENPKESKPQ 123
G CGV T CA GL C ++ PL AL G+G C+ A AP AE ES
Sbjct: 67 LGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEAGSPESPES 126
Query: 124 AGTARPQDVNR------RDQQRNPGTSTTPSQPNSAGVQDTEM----GPCRRHLDSVLQQ 173
+ ++ ++ + + S + T + PCR L V++
Sbjct: 127 TEITEEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIELYRVVES 186
Query: 174 LQTEVYRGAQTL---YVPNCDHRGFYRKRQCRSSQGQRRGPCWCV-DRMGKSLPGSPDGN 229
L + + Y+PNC+ GFY RQC +S G CWCV GK +PGSP+
Sbjct: 187 LAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIR 246
Query: 230 GSSSC 234
G +C
Sbjct: 247 GDPNC 251
>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan (testican) 2 isoform 2 [Homo sapiens]
Length = 424
Score = 54.7 bits (130), Expect = 7e-08
Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 159 EMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRM 218
E PC L+ + Q+Q E + +++P+CD G+YRK QC S G CWCVD++
Sbjct: 309 EKPPCLAELERI--QIQ-EAAKKKPGIFIPSCDEDGYYRKMQCDQSSGD----CWCVDQL 361
Query: 219 GKSLPGSPDGNGSSSC 234
G L G+ +GS C
Sbjct: 362 GLELTGTRT-HGSPDC 376
>gi|93141003 testican 3 isoform 1 [Homo sapiens]
Length = 433
Score = 52.0 bits (123), Expect = 5e-07
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
Query: 162 PCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKS 221
PC+ L ++ ++ + G Y+P CD G+Y+ QC S GQ CWCVDR G
Sbjct: 313 PCQTELSNIQKRQGVKKLLGQ---YIPLCDEDGYYKPTQCHGSVGQ----CWCVDRYGNE 365
Query: 222 LPGSPDGNGSSSC 234
+ GS NG + C
Sbjct: 366 VMGSRI-NGVADC 377
>gi|93141001 testican 3 isoform 2 [Homo sapiens]
Length = 436
Score = 52.0 bits (123), Expect = 5e-07
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
Query: 162 PCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKS 221
PC+ L ++ ++ + G Y+P CD G+Y+ QC S GQ CWCVDR G
Sbjct: 316 PCQTELSNIQKRQGVKKLLGQ---YIPLCDEDGYYKPTQCHGSVGQ----CWCVDRYGNE 368
Query: 222 LPGSPDGNGSSSC 234
+ GS NG + C
Sbjct: 369 VMGSRI-NGVADC 380
>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan 1 precursor [Homo sapiens]
Length = 439
Score = 51.6 bits (122), Expect = 6e-07
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 8/73 (10%)
Query: 162 PCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKS 221
PC+ ++ + + + + GA ++P C+ G+Y+ QC S GQ CWCVD+ G
Sbjct: 312 PCQNEMNRIQKLSKGKSLLGA---FIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364
Query: 222 LPGSPDGNGSSSC 234
L GS G+ SC
Sbjct: 365 LAGSRK-QGAVSC 376
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 50.1 bits (118), Expect = 2e-06
Identities = 24/54 (44%), Positives = 28/54 (51%), Gaps = 6/54 (11%)
Query: 183 QTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPT 236
+ L+VP+C G Y QC S G CWCV+ GK LPGS G CPT
Sbjct: 613 ERLFVPSCTTEGSYEDVQCFS------GECWCVNSWGKELPGSRVRGGQPRCPT 660
Score = 49.7 bits (117), Expect = 2e-06
Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Query: 186 YVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSS 239
YVP+C G Y+ QC Q GPCWCVD GK + G+ SC G S
Sbjct: 315 YVPSCRRNGDYQAVQC-----QTEGPCWCVDAQGKEMHGTRQQGEPPSCAEGQS 363
Score = 40.8 bits (94), Expect = 0.001
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 11/81 (13%)
Query: 161 GPCRRHLDSVLQQLQTEVYRGAQ----TLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVD 216
G R D Q+ + + G+Q TL+VP C G + QC +S+ C+CVD
Sbjct: 654 GQPRCPTDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSE------CYCVD 707
Query: 217 RMGKSLPGSPDGNGS-SSCPT 236
G+++PG+ G CPT
Sbjct: 708 AEGQAIPGTRSAIGKPKKCPT 728
Score = 40.4 bits (93), Expect = 0.001
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 6/53 (11%)
Query: 186 YVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSS--SCPT 236
Y+P CD G + QC + G CWCVD G +PGS CPT
Sbjct: 1027 YMPQCDAFGSWEPVQCHAGTGH----CWCVDEKGGFIPGSLTARSLQIPQCPT 1075
Score = 37.4 bits (85), Expect = 0.012
Identities = 21/64 (32%), Positives = 25/64 (39%), Gaps = 4/64 (6%)
Query: 172 QQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGS 231
Q L + T Y+P C G Y QC Q Q CWCVD G + G+
Sbjct: 102 QILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQ----CWCVDAEGMEVYGTRQLGRP 157
Query: 232 SSCP 235
CP
Sbjct: 158 KRCP 161
Score = 33.9 bits (76), Expect = 0.13
Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 5/50 (10%)
Query: 186 YVPNCDHR-GFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSC 234
YVP C G + QC +QG CWCV G+ +PG+ G +C
Sbjct: 1165 YVPACRAEDGGFSPVQCDQAQGS----CWCVMDSGEEVPGTRVTGGQPAC 1210
Score = 33.1 bits (74), Expect = 0.22
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 4/62 (6%)
Query: 173 QLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSS 232
+LQ E Q YVP C G ++ QC++ CWCV G + GS
Sbjct: 35 ELQRETAFLKQADYVPQCAEDGSFQTVQCQNDGRS----CWCVGANGSEVLGSRQPGRPV 90
Query: 233 SC 234
+C
Sbjct: 91 AC 92
>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
Length = 480
Score = 48.5 bits (114), Expect = 5e-06
Identities = 31/85 (36%), Positives = 36/85 (42%), Gaps = 8/85 (9%)
Query: 11 LLLLALLLAASPGGALARCPGCGQGVQAGCPGGCV--------EEEDGGSPAEGCAEAEG 62
LL L LLL A+P A G + AGCP C E +GG + C E
Sbjct: 8 LLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARDACGCCEV 67
Query: 63 CLRREGQECGVYTPNCAPGLQCHPP 87
C EG CG+ C GLQC P
Sbjct: 68 CGAPEGAACGLQEGPCGEGLQCVVP 92
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 45.4 bits (106), Expect = 4e-05
Identities = 63/260 (24%), Positives = 87/260 (33%), Gaps = 72/260 (27%)
Query: 27 ARC-PGCGQGVQAGCPGG-------CVEEEDGGSPAEGCAEAEGCLRREGQECGVYTPNC 78
ARC PG G C G CV+E + + C C+ G Y C
Sbjct: 774 ARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGS----YRCEC 829
Query: 79 APGLQCHPPKDDEAPLRALLLGRGRCLPARAPAVAEENPKESKPQAGTARP--------- 129
G + DD R C+ PA E+ + AG AR
Sbjct: 830 RSGYEF---ADD----------RHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFS 876
Query: 130 --------------QDVNRRDQQR---------NPGTSTTPSQPNSAG-----VQDT--E 159
DV+ + R PG+ + QP G + D+
Sbjct: 877 CACLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSS 936
Query: 160 MGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMG 219
+ PC + Q Y GA+ ++P CD +G + QC S G CWCVD G
Sbjct: 937 LTPCEQQQRHAQAQY---AYPGAR-FHIPQCDEQGNFLPLQCHGSTGF----CWCVDPDG 988
Query: 220 KSLPGSPDGNGSSSCPTGSS 239
+PG+ GS+ G S
Sbjct: 989 HEVPGTQTPPGSTPPHCGPS 1008
Score = 41.6 bits (96), Expect = 6e-04
Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 16/104 (15%)
Query: 136 DQQRNPGTSTTP-SQPNSAGV--QDTEMGP--CRRHLDSVLQQLQTEVYRGA--QTLYVP 188
D PGT T P S P G + T+ P C R +++L+ Y G YVP
Sbjct: 987 DGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICERWRENLLEH-----YGGTPRDDQYVP 1041
Query: 189 NCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSS 232
CD G + QC CWCVD+ G+ + G+ G++
Sbjct: 1042 QCDDLGHFIPLQCHGKSDF----CWCVDKDGREVQGTRSQPGTT 1081
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 44.3 bits (103), Expect = 1e-04
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 4/41 (9%)
Query: 185 LYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGS 225
L+VP CD G Y QC S G CWCVDR G+ + G+
Sbjct: 873 LFVPECDAHGHYAPTQCHGSTGY----CWCVDRDGREVEGT 909
>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
sapiens]
Length = 278
Score = 43.1 bits (100), Expect = 2e-04
Identities = 37/108 (34%), Positives = 41/108 (37%), Gaps = 10/108 (9%)
Query: 10 LLLLLALLLAASPGGAL----ARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCLR 65
LLLLL LL SP + R P CG GCP G S + C CL
Sbjct: 12 LLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISALDECGCCARCLG 71
Query: 66 REGQECGVYT-PNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARAPAV 112
EG CG C PGL C AP G G C+ A+ V
Sbjct: 72 AEGASCGGRAGGRCGPGLVCASQAAGAAP-----EGTGLCVCAQRGTV 114
>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
Length = 457
Score = 40.4 bits (93), Expect = 0.001
Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
Query: 175 QTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSC 234
Q + + Q +++P C+ G Y + QC S G CWCV G+ + G+ + + C
Sbjct: 98 QEQARKEFQQVFIPECNDDGTYSQVQCHSYTGY----CWCVTPNGRPISGTAVAHKTPRC 153
Query: 235 P 235
P
Sbjct: 154 P 154
Score = 35.8 bits (81), Expect = 0.034
Identities = 26/111 (23%), Positives = 41/111 (36%), Gaps = 8/111 (7%)
Query: 116 NPKESKPQAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGVQDTEMGPCRRHLDSVLQQLQ 175
N ++ A +PQ R P T + + C + S L++ +
Sbjct: 180 NSDDAAAPALETQPQGDEEDIASRYPTLWTEQVKSRQNKTNKNSVSSCDQEHQSALEEAK 239
Query: 176 TEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCV-DRMGKSLPGS 225
+ +P C H G Y+ QC S G CWCV G+ +PG+
Sbjct: 240 QPKN---DNVVIPECAHGGLYKPVQCHPSTGY----CWCVLVDTGRPIPGT 283
>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
[Homo sapiens]
Length = 435
Score = 38.9 bits (89), Expect = 0.004
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 8/79 (10%)
Query: 156 QDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCV 215
+D CR L+Q + + + ++VP C G + + QC + G CWCV
Sbjct: 88 KDAGQSKCRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTGY----CWCV 139
Query: 216 DRMGKSLPGSPDGNGSSSC 234
GK + GS N + C
Sbjct: 140 TPDGKPISGSSVQNKTPVC 158
Score = 38.5 bits (88), Expect = 0.005
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 9/89 (10%)
Query: 148 SQPNSAGVQDTE-MGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQG 206
S+ N+ ++++E + C + S L++ Q G + +P C G Y+ QC S G
Sbjct: 211 SKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREG---IVIPECAPGGLYKPVQCHQSTG 267
Query: 207 QRRGPCWCV-DRMGKSLPGSPDGNGSSSC 234
CWCV G+ LPG+ SC
Sbjct: 268 Y----CWCVLVDTGRPLPGTSTRYVMPSC 292
>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
[Homo sapiens]
Length = 434
Score = 38.9 bits (89), Expect = 0.004
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 8/79 (10%)
Query: 156 QDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCV 215
+D CR L+Q + + + ++VP C G + + QC + G CWCV
Sbjct: 88 KDAGQSKCRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTGY----CWCV 139
Query: 216 DRMGKSLPGSPDGNGSSSC 234
GK + GS N + C
Sbjct: 140 TPDGKPISGSSVQNKTPVC 158
Score = 38.5 bits (88), Expect = 0.005
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 9/89 (10%)
Query: 148 SQPNSAGVQDTE-MGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQG 206
S+ N+ ++++E + C + S L++ Q G + +P C G Y+ QC S G
Sbjct: 211 SKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREG---IVIPECAPGGLYKPVQCHQSTG 267
Query: 207 QRRGPCWCV-DRMGKSLPGSPDGNGSSSC 234
CWCV G+ LPG+ SC
Sbjct: 268 Y----CWCVLVDTGRPLPGTSTRYVMPSC 292
>gi|17511255 poly(A) binding protein interacting protein 1 isoform 1
[Homo sapiens]
Length = 479
Score = 35.8 bits (81), Expect = 0.034
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 12/115 (10%)
Query: 28 RCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCLRREGQ--ECGVYTP--------N 77
R PG G+G G G E GG P G AE + Q G P
Sbjct: 7 RAPGAGRGRSRGLGRGGGGPEGGGFP-NGAGPAERARHQPPQPKAPGFLQPPPLRQPRTT 65
Query: 78 CAPGLQCHPPKDDEAPLRALLLGRGRCLPARAPAVAEENPKESKPQAGTARPQDV 132
PG QC P + P R L + P RAP +++ + ++ A+PQ V
Sbjct: 66 PPPGAQCEVPASPQRPSRPGALPE-QTRPLRAPPSSQDKIPQQNSESAMAKPQVV 119
>gi|122891874 keratin associated protein 5-5 [Homo sapiens]
Length = 237
Score = 35.4 bits (80), Expect = 0.044
Identities = 24/64 (37%), Positives = 25/64 (39%), Gaps = 8/64 (12%)
Query: 23 GGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTPNCAPGL 82
GG + C GCG G GC GC G GCA GC G C V C P
Sbjct: 22 GGCGSGCGGCGSGC-GGCGSGC---GGCGGCGSGCAGCGGC----GSGCCVPVCCCKPMC 73
Query: 83 QCHP 86
C P
Sbjct: 74 CCVP 77
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 35.0 bits (79), Expect = 0.058
Identities = 26/82 (31%), Positives = 33/82 (40%), Gaps = 11/82 (13%)
Query: 10 LLLLLALLLAASPGGALARCPGCGQGVQAGCPG----GCVEEEDGGSPAEGCAEAEGCLR 65
LL LLL P + + CG A CP GC+ G + C C R
Sbjct: 10 LLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLL----GETRDACGCCPMCAR 65
Query: 66 REGQEC---GVYTPNCAPGLQC 84
EG+ C G CAPG++C
Sbjct: 66 GEGEPCGGGGAGRGYCAPGMEC 87
>gi|166795236 tumor-associated calcium signal transducer 2 precursor
[Homo sapiens]
Length = 323
Score = 34.7 bits (78), Expect = 0.076
Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 5/35 (14%)
Query: 185 LYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMG 219
LY P+CD G ++ RQC + CWCV+ +G
Sbjct: 103 LYDPDCDPEGRFKARQCNQT-----SVCWCVNSVG 132
>gi|145199237 transcription elongation factor B polypeptide 3
binding protein 1 [Homo sapiens]
Length = 1221
Score = 34.7 bits (78), Expect = 0.076
Identities = 26/112 (23%), Positives = 44/112 (39%), Gaps = 19/112 (16%)
Query: 41 PGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVY-TPNCAPGLQCHPPKDDEAPLRALLL 99
P +DGG P EG + + ++ G P+C G Q D+
Sbjct: 359 PAQVQSSQDGGCPKEG--------KPKKKKTGAPPAPSCKDGAQGKDKTKDK-------- 402
Query: 100 GRGRCLPARAPAVAEENPKESKPQAGTARPQDVNRRDQQRNPGTSTTPSQPN 151
GRGR P P ++ P+ S P+ RP+ ++ P ++ +P+
Sbjct: 403 GRGR--PVEKPRADKKGPQASSPRRKAERPEGTKKKPSSATPVATSGKGRPD 452
>gi|218505670 epithelial cell adhesion molecule precursor [Homo
sapiens]
Length = 314
Score = 34.3 bits (77), Expect = 0.099
Identities = 13/35 (37%), Positives = 19/35 (54%), Gaps = 5/35 (14%)
Query: 185 LYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMG 219
LY P+CD G ++ +QC + CWCV+ G
Sbjct: 94 LYDPDCDESGLFKAKQCNGT-----SMCWCVNTAG 123
>gi|51972220 keratin associated protein 5-2 [Homo sapiens]
Length = 177
Score = 33.9 bits (76), Expect = 0.13
Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 8/62 (12%)
Query: 29 CPGCGQGVQAGCPGGCVEEEDG-GSPAEGCAEAE-GCLRREGQECGVYTPNCAP-GLQCH 85
C GC +G +GC GGC G GS GC GC G CG + +C G +C+
Sbjct: 3 CCGCSRGCGSGC-GGCGSSCGGCGSGCGGCGSGRGGC----GSGCGGCSSSCGGCGSRCY 57
Query: 86 PP 87
P
Sbjct: 58 VP 59
Score = 29.6 bits (65), Expect = 2.4
Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 13/58 (22%)
Query: 23 GGALARCPGCGQGVQAGCPGGCVEEEDG-GSPAEGCAEA-EGCLRREGQECGVYTPNC 78
GG + C GCG G GGC G GS GC+ + GC G C Y P C
Sbjct: 15 GGCGSSCGGCGSGC-----GGCGSGRGGCGSGCGGCSSSCGGC----GSRC--YVPVC 61
>gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]
Length = 654
Score = 33.5 bits (75), Expect = 0.17
Identities = 58/232 (25%), Positives = 82/232 (35%), Gaps = 25/232 (10%)
Query: 33 GQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTPNCA--PGLQCHPP--- 87
G + G G E+ D GS A G G R GQ+ P PG++ P
Sbjct: 288 GDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIG 347
Query: 88 KDDEAPLRALLLGRGRCLPARAPAVAEEN------PKESKPQAGTARPQ-DVNRRDQQRN 140
E L L +G A P E PK + ++GT P+ R ++ +
Sbjct: 348 PQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGD 407
Query: 141 PGTSTTPSQPNSAGVQD-TEMGPCRRHLDSVLQQLQTEVYRGA------QTLYVPNCDHR 193
G P G Q TE+ +L LQ++ T G Q L P +
Sbjct: 408 SGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQG 467
Query: 194 -----GFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG 240
G ++ + S+G P ++ G LPG P NG G SG
Sbjct: 468 SPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKG-EKGDSG 518
>gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens]
Length = 642
Score = 33.5 bits (75), Expect = 0.17
Identities = 58/232 (25%), Positives = 82/232 (35%), Gaps = 25/232 (10%)
Query: 33 GQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTPNCA--PGLQCHPP--- 87
G + G G E+ D GS A G G R GQ+ P PG++ P
Sbjct: 288 GDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIG 347
Query: 88 KDDEAPLRALLLGRGRCLPARAPAVAEEN------PKESKPQAGTARPQ-DVNRRDQQRN 140
E L L +G A P E PK + ++GT P+ R ++ +
Sbjct: 348 PQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGD 407
Query: 141 PGTSTTPSQPNSAGVQD-TEMGPCRRHLDSVLQQLQTEVYRGA------QTLYVPNCDHR 193
G P G Q TE+ +L LQ++ T G Q L P +
Sbjct: 408 SGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQG 467
Query: 194 -----GFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG 240
G ++ + S+G P ++ G LPG P NG G SG
Sbjct: 468 SPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKG-EKGDSG 518
>gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
Length = 978
Score = 32.7 bits (73), Expect = 0.29
Identities = 46/176 (26%), Positives = 64/176 (36%), Gaps = 21/176 (11%)
Query: 79 APGLQCHPPKDDE--APLRA---LLLGRGRCLPARAPAVAEENPKESKPQAGTARPQDVN 133
AP + PK + P+R L + G P +P + P AG+A D +
Sbjct: 278 APSISTVEPKREREGGPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSP-AGSAANTD-S 335
Query: 134 RRDQQRNPGTSTTPSQPNSAG--VQDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCD 191
+ N G ST G + T + RR + L QL G + L +P+
Sbjct: 336 GVEMTGNAGGSTEDLSSLDEGPCIAGTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLS 395
Query: 192 HRGFYRKRQC--------RSSQGQRRGPCWCVDRMGKSL----PGSPDGNGSSSCP 235
H G R+ RSS + V R PGSP NG+SS P
Sbjct: 396 HTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLP 451
>gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]
Length = 1106
Score = 32.7 bits (73), Expect = 0.29
Identities = 46/176 (26%), Positives = 64/176 (36%), Gaps = 21/176 (11%)
Query: 79 APGLQCHPPKDDE--APLRA---LLLGRGRCLPARAPAVAEENPKESKPQAGTARPQDVN 133
AP + PK + P+R L + G P +P + P AG+A D +
Sbjct: 406 APSISTVEPKREREGGPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSP-AGSAANTD-S 463
Query: 134 RRDQQRNPGTSTTPSQPNSAG--VQDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCD 191
+ N G ST G + T + RR + L QL G + L +P+
Sbjct: 464 GVEMTGNAGGSTEDLSSLDEGPCIAGTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLS 523
Query: 192 HRGFYRKRQC--------RSSQGQRRGPCWCVDRMGKSL----PGSPDGNGSSSCP 235
H G R+ RSS + V R PGSP NG+SS P
Sbjct: 524 HTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLP 579
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.136 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,857,937
Number of Sequences: 37866
Number of extensions: 767623
Number of successful extensions: 3480
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 3269
Number of HSP's gapped (non-prelim): 334
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.