Guide to the Human Genome
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Name: HTRA1 Sequence: fasta or formatted (480aa) NCBI GI: 4506141
Description:

HtrA serine peptidase 1 precursor

Referenced in:

Growth Hormone and Related Hormones
Protease Inhibitors
Serine Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.6         46           2
 C cysteine            3.3         16           2
 D aspartate           5.2         25           1
 E glutamate           6.2         30           2
 F phenylalanine       2.1         10           1
 G glycine             8.8         42           2
 H histidine           1.9          9           1
 I isoleucine          7.5         36           2
 K lysine              5.6         27           3
 L leucine             8.1         39           6
 M methionine          1.2          6           2
 N asparagine          3.8         18           1
 P proline             6.2         30           2
 Q glutamine           3.3         16           1
 R arginine            6.5         31           3
 S serine              6.9         33           2
 T threonine           4.0         19           2
 V valine              8.3         40           2
 W tryptophan          0.0          0           0
 Y tyrosine            1.5          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   HtrA serine peptidase 1 precursor 
HTRA3                 0.523   HtrA serine peptidase 3 
HTRA4                 0.483   HtrA serine peptidase 4 precursor 
HTRA2                 0.328   HtrA serine peptidase 2 isoform 1 preproprotein [Homo...
HTRA2                 0.097   HtrA serine peptidase 2 isoform 2 
IGFBP7                0.086   insulin-like growth factor binding protein 7 
KAZALD1               0.071   Kazal-type serine peptidase inhibitor domain 1 precu...
IGFBPL1               0.068   insulin-like growth factor binding protein-like 1 [H...
IGFBP3                0.038   insulin-like growth factor binding protein 3 isoform...
IGFBP3                0.038   insulin-like growth factor binding protein 3 isoform...
IGFBP2                0.034   insulin-like growth factor binding protein 2, 36kDa ...
IGFBP1                0.032   insulin-like growth factor binding protein 1 precurso...
IGFBP5                0.030   insulin-like growth factor binding protein 5 
IGFBP4                0.029   insulin-like growth factor binding protein 4 precurs...
ESM1                  0.027   endothelial cell-specific molecule 1 isoform a precur...
ESM1                  0.027   endothelial cell-specific molecule 1 isoform b prec...
IGFBP6                0.026   insulin-like growth factor binding protein 6 
CRIM1                 0.025   cysteine-rich motor neuron 1 
AGRN                  0.023   agrin 
NOV                   0.023   nephroblastoma overexpressed precursor 
GSC2                  0.022   goosecoid homeobox 2 
CYR61                 0.020   cysteine-rich, angiogenic inducer, 61 
CTGF                  0.019   connective tissue growth factor 
PDZK1                 0.019   PDZ domain containing 1 
WISP2                 0.016   WNT1 inducible signaling pathway protein 2 precursor ...
WISP3                 0.016   WNT1 inducible signaling pathway protein 3 isoform 3...
WISP3                 0.016   WNT1 inducible signaling pathway protein 3 isoform 1 ...
SLC9A3R1              0.016   sodium/hydrogen exchanger regulatory factor 1 
LCE1B                 0.016   late cornified envelope 1B 
LCE1C                 0.015   late cornified envelope 1C 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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