Guide to the Human Genome
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Name: IGFBP4 Sequence: fasta or formatted (258aa) NCBI GI: 62243290
Description:

insulin-like growth factor binding protein 4 precursor

Referenced in:

Growth Hormone and Related Hormones
Ovary, Uterus and Placenta

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.4         19           2
 C cysteine            8.1         21           2
 D aspartate           5.0         13           1
 E glutamate           7.4         19           2
 F phenylalanine       1.6          4           1
 G glycine            10.1         26           2
 H histidine           4.3         11           1
 I isoleucine          2.7          7           2
 K lysine              4.7         12           1
 L leucine            10.1         26           3
 M methionine          1.9          5           1
 N asparagine          2.3          6           2
 P proline             9.7         25           2
 Q glutamine           3.9         10           1
 R arginine            7.4         19           2
 S serine              5.8         15           1
 T threonine           2.3          6           1
 V valine              3.9         10           1
 W tryptophan          0.4          1           1
 Y tyrosine            1.2          3           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   insulin-like growth factor binding protein 4 precurs... 
IGFBP5                0.290   insulin-like growth factor binding protein 5 
IGFBP2                0.285   insulin-like growth factor binding protein 2, 36kDa ...
IGFBP3                0.238   insulin-like growth factor binding protein 3 isoform...
IGFBP3                0.238   insulin-like growth factor binding protein 3 isoform...
IGFBP1                0.223   insulin-like growth factor binding protein 1 precurso...
IGFBP6                0.185   insulin-like growth factor binding protein 6 
HTRA1                 0.051   HtrA serine peptidase 1 precursor 
NID2                  0.047   nidogen 2 precursor 
ESM1                  0.043   endothelial cell-specific molecule 1 isoform b prec...
ESM1                  0.043   endothelial cell-specific molecule 1 isoform a precur...
CRIM1                 0.039   cysteine-rich motor neuron 1 
IGFBPL1               0.036   insulin-like growth factor binding protein-like 1 [H...
SMOC2                 0.036   SPARC related modular calcium binding 2 
SPOCK1                0.036   sparc/osteonectin, cwcv and kazal-like domains proteo...
IGFBP7                0.034   insulin-like growth factor binding protein 7 
NID1                  0.034   nidogen 1 precursor 
SPOCK3                0.032   testican 3 isoform 1 
SPOCK3                0.032   testican 3 isoform 2 
TG                    0.032   thyroglobulin 
SMOC1                 0.032   secreted modular calcium-binding protein 1 isoform 1...
SMOC1                 0.032   secreted modular calcium-binding protein 1 isoform 2...
SPOCK2                0.026   sparc/osteonectin, cwcv and kazal-like domains proteo...
CYR61                 0.026   cysteine-rich, angiogenic inducer, 61 
CTGF                  0.024   connective tissue growth factor 
CD74                  0.024   CD74 antigen isoform a 
HTRA3                 0.022   HtrA serine peptidase 3 
WISP2                 0.021   WNT1 inducible signaling pathway protein 2 precursor ...
KAZALD1               0.019   Kazal-type serine peptidase inhibitor domain 1 precu...
HDAC1                 0.015   histone deacetylase 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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