BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|17986001 major histocompatibility complex, class I, B precursor [Homo sapiens] (362 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|17986001 major histocompatibility complex, class I, B precurs... 744 0.0 gi|52630342 major histocompatibility complex, class I, C precurs... 641 0.0 gi|24797067 major histocompatibility complex, class I, A precurs... 640 0.0 gi|62912479 major histocompatibility complex, class I, E precurs... 575 e-164 gi|4504415 major histocompatibility complex, class I, G precurso... 572 e-163 gi|149158702 major histocompatibility complex, class I, F isofor... 568 e-162 gi|149158698 major histocompatibility complex, class I, F isofor... 567 e-162 gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 500 e-142 gi|149158700 major histocompatibility complex, class I, F isofor... 320 1e-87 gi|4504417 major histocompatibility complex, class I-related [Ho... 233 3e-61 gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 215 4e-56 gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 207 1e-53 gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 201 6e-52 gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 196 2e-50 gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 177 2e-44 gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 158 8e-39 gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 145 5e-35 gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 142 6e-34 gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 142 6e-34 gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 140 2e-33 gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 118 9e-27 gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 118 9e-27 gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 108 7e-24 gi|239740918 PREDICTED: similar to major histocompatibility comp... 74 3e-13 gi|169168591 PREDICTED: similar to major histocompatibility comp... 73 3e-13 gi|4502649 CD1D antigen precursor [Homo sapiens] 73 5e-13 gi|239740920 PREDICTED: similar to major histocompatibility comp... 72 8e-13 gi|24797076 major histocompatibility complex, class II, DP beta ... 71 2e-12 gi|110618224 CD1A antigen precursor [Homo sapiens] 71 2e-12 gi|239758095 PREDICTED: similar to major histocompatibility comp... 70 2e-12 >gi|17986001 major histocompatibility complex, class I, B precursor [Homo sapiens] Length = 362 Score = 744 bits (1922), Expect = 0.0 Identities = 362/362 (100%), Positives = 362/362 (100%) Query: 1 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF 60 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF Sbjct: 1 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF 60 Query: 61 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ 120 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ Sbjct: 61 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ 120 Query: 121 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR 180 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR Sbjct: 121 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR 180 Query: 181 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT 240 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT Sbjct: 181 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT 240 Query: 241 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 300 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP Sbjct: 241 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 300 Query: 301 SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSL 360 SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSL Sbjct: 301 SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSL 360 Query: 361 TA 362 TA Sbjct: 361 TA 362 >gi|52630342 major histocompatibility complex, class I, C precursor [Homo sapiens] Length = 366 Score = 641 bits (1654), Expect = 0.0 Identities = 313/361 (86%), Positives = 331/361 (91%), Gaps = 1/361 (0%) Query: 1 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF 60 M VMAPR +LLLLS LALTETWA SHSMRYF T+VSRPGRGEPRFISVGYVDDTQFVRF Sbjct: 1 MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRF 60 Query: 61 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ 120 DSDAASPR EPRAPW+EQEGPEYWDR TQ YK QAQ DR SLRNLRGYYNQSE GSHTLQ Sbjct: 61 DSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQ 120 Query: 121 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR 180 M GCD+GPDGRLLRG+DQ AYDGKDYIALNEDLRSWTAADTAAQITQRK EAAR AEQ Sbjct: 121 RMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQL 180 Query: 181 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT 240 RAYLEG CVEWLRRYLENGK+ L+RA+PPKTHVTHHP+SDHEATLRCWALGFYPAEITLT Sbjct: 181 RAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLT 240 Query: 241 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 300 WQRDGEDQTQDTELVETRPAGD TFQKWAAVVVPSG+EQRYTCH+QHEGL +PLTL WEP Sbjct: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEP 300 Query: 301 SSQSTVPIVGIVAGLAVLAVV-VIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVS 359 SSQ T+PI+GIVAGLAVL V+ V+GAVV A+MCRRKSSGGKGGS SQAACS+SAQGSD S Sbjct: 301 SSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDES 360 Query: 360 L 360 L Sbjct: 361 L 361 >gi|24797067 major histocompatibility complex, class I, A precursor [Homo sapiens] Length = 365 Score = 640 bits (1650), Expect = 0.0 Identities = 310/362 (85%), Positives = 329/362 (90%) Query: 1 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF 60 M VMAPRT+LLLLS ALALT+TWAGSHSMRYF+TSVSRPGRGEPRFI+VGYVDDTQFVRF Sbjct: 1 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF 60 Query: 61 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ 120 DSDAAS R EPRAPWIEQEGPEYWD+ T+ KAQ+QTDR L LRGYYNQSEAGSHT+Q Sbjct: 61 DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ 120 Query: 121 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR 180 MYGCDVG DGR LRG+ Q AYDGKDYIALNEDLRSWTAAD AAQIT+RKWEAA EAEQ Sbjct: 121 IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL 180 Query: 181 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT 240 RAYL+G CVEWLRRYLENGK+ L+R DPPKTH+THHPISDHEATLRCWALGFYPAEITLT Sbjct: 181 RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT 240 Query: 241 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 300 WQRDGEDQTQDTELVETRPAGD TFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWE Sbjct: 241 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL 300 Query: 301 SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSL 360 SSQ T+PIVGI+AGL +L V+ GAVVAAVM RRKSS KGGSY+QAA SDSAQGSDVSL Sbjct: 301 SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSL 360 Query: 361 TA 362 TA Sbjct: 361 TA 362 >gi|62912479 major histocompatibility complex, class I, E precursor [Homo sapiens] Length = 358 Score = 575 bits (1482), Expect = e-164 Identities = 274/354 (77%), Positives = 310/354 (87%) Query: 4 MAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSD 63 M T+LLLLS ALALT+TWAGSHS++YF+TSVSRPGRGEPRFISVGYVDDTQFVRFD+D Sbjct: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60 Query: 64 AASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY 123 AASPR PRAPW+EQEG EYWDR T+ + AQ R +LR LRGYYNQSEAGSHTLQ M+ Sbjct: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120 Query: 124 GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAY 183 GC++GPDGR LRG++Q+AYDGKDY+ LNEDLRSWTA DTAAQI+++K A EAE +RAY Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180 Query: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243 LE CVEWL +YLE GK+ L +PPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQ+ Sbjct: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240 Query: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303 DGE TQDTELVETRPAGD TFQKWAAVVVPSGEEQRYTCHVQHEGLP+P+TLRW+P+SQ Sbjct: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300 Query: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSD 357 T+PIVGI+AGL +L VV GAVVAAV+ R+KSSGGKGGSYS+A SDSAQGS+ Sbjct: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSE 354 >gi|4504415 major histocompatibility complex, class I, G precursor [Homo sapiens] Length = 338 Score = 572 bits (1475), Expect = e-163 Identities = 273/337 (81%), Positives = 300/337 (89%) Query: 1 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF 60 M+VMAPRT+ LLLS AL LTETWAGSHSMRYF +VSRPGRGEPRFI++GYVDDTQFVRF Sbjct: 1 MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF 60 Query: 61 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ 120 DSD+A PR EPRAPW+EQEGPEYW+ T+ KA AQTDR +L+ LRGYYNQSEA SHTLQ Sbjct: 61 DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ 120 Query: 121 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR 180 M GCD+G DGRLLRG++QYAYDGKDY+ALNEDLRSWTAADTAAQI++RK EAA AEQR Sbjct: 121 WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR 180 Query: 181 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT 240 RAYLEG CVEWL RYLENGK+ L+RADPPKTHVTHHP+ D+EATLRCWALGFYPAEI LT Sbjct: 181 RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT 240 Query: 241 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 300 WQRDGEDQTQD ELVETRPAGD TFQKWAAVVVPSGEEQRYTCHVQHEGLP+PL LRW+ Sbjct: 241 WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ 300 Query: 301 SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSS 337 SS T+PI+GIVAGL VLA VV GA VAAV+ R+KSS Sbjct: 301 SSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337 >gi|149158702 major histocompatibility complex, class I, F isoform 1 precursor [Homo sapiens] Length = 442 Score = 568 bits (1464), Expect = e-162 Identities = 276/353 (78%), Positives = 302/353 (85%) Query: 4 MAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSD 63 MAPR++LLLLS ALALT+TWAGSHS+RYF T+VSRPGRGEPR+I+V YVDDTQF+RFDSD Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60 Query: 64 AASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY 123 AA PR EPR PW+EQEGP+YW+ T KA AQTDR +LRNL YNQSEAGSHTLQ M Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120 Query: 124 GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAY 183 GCD+GPDGRLLRG+ Q+AYDGKDYI+LNEDLRSWTAADT AQITQR +EA AE+ R Y Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180 Query: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243 LEGEC+E LRRYLENGK+ L+RADPPK HV HHPISDHEATLRCWALGFYPAEITLTWQR Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240 Query: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303 DGE+QTQDTELVETRPAGD TFQKWAAVVVP GEEQRYTCHVQHEGLP+PL LRWE S Q Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300 Query: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGS 356 T+PIVGIVAGL VL VV GAVVAAVM R+KSS GSYSQAA G+ Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGN 353 >gi|149158698 major histocompatibility complex, class I, F isoform 2 precursor [Homo sapiens] Length = 346 Score = 567 bits (1461), Expect = e-162 Identities = 275/345 (79%), Positives = 300/345 (86%) Query: 4 MAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSD 63 MAPR++LLLLS ALALT+TWAGSHS+RYF T+VSRPGRGEPR+I+V YVDDTQF+RFDSD Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60 Query: 64 AASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY 123 AA PR EPR PW+EQEGP+YW+ T KA AQTDR +LRNL YNQSEAGSHTLQ M Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120 Query: 124 GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAY 183 GCD+GPDGRLLRG+ Q+AYDGKDYI+LNEDLRSWTAADT AQITQR +EA AE+ R Y Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180 Query: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243 LEGEC+E LRRYLENGK+ L+RADPPK HV HHPISDHEATLRCWALGFYPAEITLTWQR Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240 Query: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303 DGE+QTQDTELVETRPAGD TFQKWAAVVVP GEEQRYTCHVQHEGLP+PL LRWE S Q Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300 Query: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAA 348 T+PIVGIVAGL VL VV GAVVAAVM R+KSS GSYSQAA Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 345 >gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapiens] Length = 366 Score = 500 bits (1287), Expect = e-142 Identities = 244/325 (75%), Positives = 272/325 (83%), Gaps = 4/325 (1%) Query: 25 GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYW 84 GSHS+RYFYT+VSRPG GEPRFISVGYVDDTQFVRFDSD+A+PREEPRAPW+EQEGPEYW Sbjct: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97 Query: 85 DRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDG 144 D T+I K AQ+ R L LRGYYNQSEAGSHTLQ MYGCDVGPDGR LRG Q AYDG Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157 Query: 145 KDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLE 204 +DYIALNEDLRSWTAADTAAQIT+RK EAA AE++R YLEG CVE LRRYLE GKD L Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217 Query: 205 RADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRT 264 RADPPK HVTHHPIS+ E TLRCWALGFYP EI+LTWQR+GEDQTQD ELVETRP+GD T Sbjct: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277 Query: 265 FQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIG 324 FQKWAA+VVPSGEEQRYTC VQHEGL +PLTLRWEP Q++ I+GI+ GL +L V+ Sbjct: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEP-PQTSFLIMGIIVGLVLL---VVA 333 Query: 325 AVVAAVMCRRKSSGGKGGSYSQAAC 349 V AV+ R+K SG +G S+ +C Sbjct: 334 LVAGAVIWRKKRSGREGREGSEFSC 358 >gi|149158700 major histocompatibility complex, class I, F isoform 3 precursor [Homo sapiens] Length = 254 Score = 320 bits (820), Expect = 1e-87 Identities = 154/204 (75%), Positives = 176/204 (86%) Query: 4 MAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSD 63 MAPR++LLLLS ALALT+TWAGSHS+RYF T+VSRPGRGEPR+I+V YVDDTQF+RFDSD Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60 Query: 64 AASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY 123 AA PR EPR PW+EQEGP+YW+ T KA AQTDR +LRNL YNQSEAGSHTLQ M Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120 Query: 124 GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAY 183 GCD+GPDGRLLRG+ Q+AYDGKDYI+LNEDLRSWTAADT AQITQR +EA AE+ R Y Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180 Query: 184 LEGECVEWLRRYLENGKDKLERAD 207 LEGEC+E LRRYLENGK+ L+RA+ Sbjct: 181 LEGECLELLRRYLENGKETLQRAE 204 Score = 66.6 bits (161), Expect = 3e-11 Identities = 37/52 (71%), Positives = 39/52 (75%) Query: 297 RWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAA 348 R E S Q T+PIVGIVAGL VL VV GAVVAAVM R+KSS GSYSQAA Sbjct: 202 RAEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAA 253 >gi|4504417 major histocompatibility complex, class I-related [Homo sapiens] Length = 341 Score = 233 bits (593), Expect = 3e-61 Identities = 131/338 (38%), Positives = 191/338 (56%), Gaps = 13/338 (3%) Query: 10 LLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRE 69 LL L L + + + +HS+RYF VS P G P FISVGYVD +DS + ++ Sbjct: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTRQK 65 Query: 70 EPRAPWI-EQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVG 128 EPRAPW+ E P++W+R TQ+ + Q + L+ L+ +YN S GSHT Q M GC++ Sbjct: 66 EPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELL 123 Query: 129 PDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR-EAEQRRAYLEGE 187 DG G QYAYDG+D++ N+D SW A D A ++ WEA + E ++ +LE E Sbjct: 124 EDGSTT-GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182 Query: 188 CVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGED 247 C+ WL+R+LE GKD L+R +PP V L C A GFYP EI +TW ++GE+ Sbjct: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEE 242 Query: 248 QTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVP 307 Q+ + + P+GD T+Q WA++ + Y+CHV+H G+ L + P T+P Sbjct: 243 IVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQV---PQESETIP 299 Query: 308 IV-GIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344 +V V+G VL +V+ G V ++ RR+ G Y Sbjct: 300 LVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335 >gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sapiens] Length = 348 Score = 215 bits (548), Expect = 4e-56 Identities = 123/342 (35%), Positives = 185/342 (54%), Gaps = 9/342 (2%) Query: 6 PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65 P +LL+L L SHS+ Y + S G F ++GYVDD FV +D + Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64 Query: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG 124 S R EPR PW+ + W + +Q K + +N S+ SHTLQ + G Sbjct: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123 Query: 125 CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR-EAEQRRAY 183 C++ D G+ +Y YDG+D++ D W AA+ A T+ +WE + A Q RAY Sbjct: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182 Query: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243 LE +C L++ LE G+ L++ PP VTHH ++ TLRC AL +YP IT+ W + Sbjct: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241 Query: 244 DGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSS 302 D + ++ E + P GD T+Q W + VP GEEQRYTC V+H GL +PL + WEPS Sbjct: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301 Query: 303 QSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344 T+ ++G+++G+AV V++ ++ ++ +R+ S G G Y Sbjct: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 342 >gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] Length = 298 Score = 207 bits (527), Expect = 1e-53 Identities = 116/294 (39%), Positives = 166/294 (56%), Gaps = 8/294 (2%) Query: 10 LLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRE 69 LLLL E G +S+ Y YT +S+ P F ++G ++D QF R++S + Sbjct: 11 LLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSK--DRKS 68 Query: 70 EPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGP 129 +P W + EG E W +++Q+ KA+ E+L+++ YYN S GSH LQ +GC++ Sbjct: 69 QPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-E 126 Query: 130 DGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR-RAYLEGEC 188 + R +Y YDGKDYI N+++ +W D AAQIT++KWEA QR +AYLE EC Sbjct: 127 NNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEEC 186 Query: 189 VEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ 248 LR+YL+ K+ L+R DPP VT H + L+C A FYP +I + W R GE Sbjct: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE-- 244 Query: 249 TQDTEL-VETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPS 301 Q+ EL + G+ T+Q W V VP + Y+CHVQH L +PL + WE S Sbjct: 245 VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298 >gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sapiens] Length = 325 Score = 201 bits (512), Expect = 6e-52 Identities = 112/303 (36%), Positives = 170/303 (56%), Gaps = 9/303 (2%) Query: 45 RFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLR 103 R + +GYVDD FV +D + S R EPR PW+ + W + +Q K Sbjct: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 Query: 104 NLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTA 163 + +N S+ SHTLQ + GC++ D G+ +Y YDG+D++ D W AA+ Sbjct: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 Query: 164 AQITQRKWEAAR-EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHE 222 A T+ +WE + A Q RAYLE +C L++ LE G+ L++ PP VTHH ++ Sbjct: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197 Query: 223 ATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY 281 TLRC AL +YP IT+ W +D + ++ E + P GD T+Q W + VP GEEQRY Sbjct: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 Query: 282 TCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKG 341 TC V+H GL +PL + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G Sbjct: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316 Query: 342 GSY 344 G Y Sbjct: 317 GHY 319 >gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sapiens] Length = 334 Score = 196 bits (499), Expect = 2e-50 Identities = 117/342 (34%), Positives = 177/342 (51%), Gaps = 23/342 (6%) Query: 6 PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65 P +LL+L L SHS+ Y + S G F ++GYVDD FV +D + Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64 Query: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG 124 S R EPR PW+ + W + +Q K + +N S+ SHTLQ + G Sbjct: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123 Query: 125 CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR-EAEQRRAY 183 C++ D G+ +Y YDG+D++ D W AA+ A T+ +WE + A Q RAY Sbjct: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182 Query: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243 LE +C L++ LE G+ L++ TLRC AL +YP IT+ W + Sbjct: 183 LERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYPQNITMKWLK 227 Query: 244 DGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSS 302 D + ++ E + P GD T+Q W + VP GEEQRYTC V+H GL +PL + WEPS Sbjct: 228 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 287 Query: 303 QSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344 T+ ++G+++G+AV V++ ++ ++ +R+ S G G Y Sbjct: 288 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 328 >gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sapiens] Length = 260 Score = 177 bits (448), Expect = 2e-44 Identities = 91/231 (39%), Positives = 138/231 (59%), Gaps = 5/231 (2%) Query: 116 SHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR 175 SHTLQ + GC++ D G+ +Y YDG+D++ D W AA+ A T+ +WE + Sbjct: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85 Query: 176 -EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYP 234 A Q RAYLE +C L++ LE G+ L++ PP VTHH ++ TLRC AL +YP Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144 Query: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKP 293 IT+ W +D + ++ E + P GD T+Q W + VP GEEQRYTC V+H GL +P Sbjct: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204 Query: 294 LTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344 L + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G G Y Sbjct: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 254 >gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sapiens] Length = 246 Score = 158 bits (399), Expect = 8e-39 Identities = 85/231 (36%), Positives = 130/231 (56%), Gaps = 19/231 (8%) Query: 116 SHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR 175 SHTLQ + GC++ D G+ +Y YDG+D++ D W AA+ A T+ +WE + Sbjct: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85 Query: 176 -EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYP 234 A Q RAYLE +C L++ LE G+ L++ TLRC AL +YP Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQ---------------QVTTLRCRALNYYP 130 Query: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKP 293 IT+ W +D + ++ E + P GD T+Q W + VP GEEQRYTC V+H GL +P Sbjct: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190 Query: 294 LTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344 L + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G G Y Sbjct: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 240 >gi|167857788 MHC class I polypeptide-related sequence B [Homo sapiens] Length = 383 Score = 145 bits (366), Expect = 5e-35 Identities = 103/351 (29%), Positives = 174/351 (49%), Gaps = 34/351 (9%) Query: 9 VLLLLSAALALTETWAGS--HSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAAS 66 VLL L+ A A + HS+RY +S+ G + F++ G++D F+R+D Sbjct: 6 VLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR- 64 Query: 67 PREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGC 125 R +P+ W E G + WD T+ Q R +L +++ + G H+LQ + C Sbjct: 65 -RAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIK----DQKGGLHSLQEIRVC 119 Query: 126 DVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTA-----ADTAAQITQRKW-EAAREAEQ 179 ++ D RG + YDG+ +++ N + + T A T A W E A + + Sbjct: 120 EIHEDSST-RGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKT 178 Query: 180 RRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITL 239 ++ +C++ L+RYL++G + R PP +VT +S+ T+ C A FYP ITL Sbjct: 179 HYRAMQADCLQKLQRYLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITL 237 Query: 240 TWQRDGEDQTQDT-ELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEG------LP- 291 TW++DG + +T + + P G+ T+Q W A + GEEQR+TC+++H G +P Sbjct: 238 TWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPS 297 Query: 292 -KPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKG 341 K L L+ S ++ P V A + VI ++ C++K+S +G Sbjct: 298 GKALVLQ---SQRTDFPYVS-----AAMPCFVIIIILCVPCCKKKTSAAEG 340 >gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo sapiens] Length = 365 Score = 142 bits (357), Expect = 6e-34 Identities = 104/335 (31%), Positives = 166/335 (49%), Gaps = 26/335 (7%) Query: 9 VLLLLSAALALTETWAGSH-SMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASP 67 +L LL +L A SH S+ Y T+VS P G P F G++ Q++ ++S Sbjct: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRG 66 Query: 68 REEPRAPWI-EQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCD 126 EP W+ E + YW++ T + + + E+ + L G G +TLQ + GC+ Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120 Query: 127 VGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADT---AAQITQRKWEAAREAEQRRAY 183 +GPD + ++A +G+++ +N DL+ T A I+QR + + A + + Sbjct: 121 LGPDNTSVPTA-KFALNGEEF--MNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177 Query: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243 L C LR +LE G+ LE +PP + P S + L C A FYP E+ L + R Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237 Query: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303 +G T + P D +F +++ V SG+E Y C VQH GL +PL + E ++ Sbjct: 238 NG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295 Query: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSG 338 S+V +VGIV G+ +L +G A++ RR SG Sbjct: 296 SSVLVVGIVIGVLLLTAAAVG---GALLWRRMRSG 327 >gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo sapiens] Length = 365 Score = 142 bits (357), Expect = 6e-34 Identities = 104/335 (31%), Positives = 166/335 (49%), Gaps = 26/335 (7%) Query: 9 VLLLLSAALALTETWAGSH-SMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASP 67 +L LL +L A SH S+ Y T+VS P G P F G++ Q++ ++S Sbjct: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRG 66 Query: 68 REEPRAPWI-EQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCD 126 EP W+ E + YW++ T + + + E+ + L G G +TLQ + GC+ Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120 Query: 127 VGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADT---AAQITQRKWEAAREAEQRRAY 183 +GPD + ++A +G+++ +N DL+ T A I+QR + + A + + Sbjct: 121 LGPDNTSVPTA-KFALNGEEF--MNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177 Query: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243 L C LR +LE G+ LE +PP + P S + L C A FYP E+ L + R Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237 Query: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303 +G T + P D +F +++ V SG+E Y C VQH GL +PL + E ++ Sbjct: 238 NG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295 Query: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSG 338 S+V +VGIV G+ +L +G A++ RR SG Sbjct: 296 SSVLVVGIVIGVLLLTAAAVG---GALLWRRMRSG 327 >gi|4557751 MHC class I polypeptide-related sequence A [Homo sapiens] Length = 383 Score = 140 bits (352), Expect = 2e-33 Identities = 100/347 (28%), Positives = 164/347 (47%), Gaps = 26/347 (7%) Query: 9 VLLLLSAALALTETWAGS--HSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAAS 66 V LLL+ A + HS+RY T +S G + F++ ++D F+R D Sbjct: 6 VFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC- 64 Query: 67 PREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGC 125 R +P+ W E G + WDR T+ + R +L +++ + G H+LQ + C Sbjct: 65 -RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK----DQKEGLHSLQEIRVC 119 Query: 126 DVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWT------AADTAAQITQRKWEAAREAEQ 179 ++ D R + YDG+ +++ N + + WT A A + E A + + Sbjct: 120 EIHEDNST-RSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKT 178 Query: 180 RRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITL 239 + +C++ LRRYL++G L R PP +VT S+ T+ C A GFYP ITL Sbjct: 179 HYHAMHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITL 237 Query: 240 TWQRDGEDQTQDT-ELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEG----LPKPL 294 +W++DG + DT + + P G+ T+Q W A + GEEQR+TC+++H G P P Sbjct: 238 SWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPS 297 Query: 295 TLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKG 341 S V VA A+ +++ C++K+S +G Sbjct: 298 GKVLVLQSHWQTFHVSAVAAAAIFVIIIF----YVRCCKKKTSAAEG 340 >gi|21040355 hemochromatosis protein isoform 10 precursor [Homo sapiens] Length = 168 Score = 118 bits (295), Expect = 9e-27 Identities = 56/138 (40%), Positives = 85/138 (61%), Gaps = 3/138 (2%) Query: 208 PPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQ 266 PP VTHH ++ TLRC AL +YP IT+ W +D + ++ E + P GD T+Q Sbjct: 27 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85 Query: 267 KWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAV 326 W + VP GEEQRYTC V+H GL +PL + WEPS T+ ++G+++G+AV V++ + Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144 Query: 327 VAAVMCRRKSSGGKGGSY 344 + ++ +R+ S G G Y Sbjct: 145 LFIILRKRQGSRGAMGHY 162 >gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sapiens] Length = 256 Score = 118 bits (295), Expect = 9e-27 Identities = 56/138 (40%), Positives = 85/138 (61%), Gaps = 3/138 (2%) Query: 208 PPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQ 266 PP VTHH ++ TLRC AL +YP IT+ W +D + ++ E + P GD T+Q Sbjct: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173 Query: 267 KWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAV 326 W + VP GEEQRYTC V+H GL +PL + WEPS T+ ++G+++G+AV V++ + Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232 Query: 327 VAAVMCRRKSSGGKGGSY 344 + ++ +R+ S G G Y Sbjct: 233 LFIILRKRQGSRGAMGHY 250 Score = 49.7 bits (117), Expect = 4e-06 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 3/88 (3%) Query: 6 PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65 P +LL+L L SHS+ Y + S G F ++GYVDD FV +D + Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64 Query: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYK 92 S R EPR PW+ + W + +Q K Sbjct: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLK 92 >gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sapiens] Length = 242 Score = 108 bits (270), Expect = 7e-24 Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%) Query: 224 TLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYT 282 TLRC AL +YP IT+ W +D + ++ E + P GD T+Q W + VP GEEQRYT Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 Query: 283 CHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGG 342 C V+H GL +PL + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G G Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234 Query: 343 SY 344 Y Sbjct: 235 HY 236 Score = 49.7 bits (117), Expect = 4e-06 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 3/88 (3%) Query: 6 PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65 P +LL+L L SHS+ Y + S G F ++GYVDD FV +D + Sbjct: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64 Query: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYK 92 S R EPR PW+ + W + +Q K Sbjct: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLK 92 >gi|239740918 PREDICTED: similar to major histocompatibility complex, class II, DQ beta 1 isoform 1 [Homo sapiens] Length = 281 Score = 73.6 bits (179), Expect = 3e-13 Identities = 59/229 (25%), Positives = 94/229 (41%), Gaps = 20/229 (8%) Query: 134 LRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREA-EQRRAYLEGECVE-- 190 +RG +Y Y+ ++Y + D+ + A W + +E E+ RA L+ C Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNY 115 Query: 191 --WLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ 248 LR L+ + P +T +H L C FYPA+I + W R+ +++ Sbjct: 116 QLELRTTLQRRVEPTVTISPSRTEALNH-----HNLLVCSVTDFYPAQIKVRWFRNDQEE 170 Query: 249 TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVP- 307 T GD TFQ + + YTCHV+H L P+ + W S+S Sbjct: 171 TTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSK 230 Query: 308 ----IVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY--SQAACS 350 I G V GL L +G ++ + + GK G + +Q CS Sbjct: 231 MLSGIGGFVLGLIFLG---LGLIIHHRSQKGEEPQGKRGRWAVTQTLCS 276 >gi|169168591 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 isoform 1 [Homo sapiens] Length = 261 Score = 73.2 bits (178), Expect = 3e-13 Identities = 53/200 (26%), Positives = 84/200 (42%), Gaps = 15/200 (7%) Query: 134 LRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREA-EQRRAYLEGECVE-- 190 +RG +Y Y+ ++Y + D+ + A W + +E E+ RA ++ C Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNY 115 Query: 191 --WLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ 248 LR L+ + P +T +H L C FYPA+I + W R+ +++ Sbjct: 116 QLELRTTLQRRVEPTVTISPSRTEALNH-----HNLLVCSVTDFYPAQIKVRWFRNDQEE 170 Query: 249 TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVP- 307 T GD TFQ + + YTCHV+H L P+T+ W S+S Sbjct: 171 TAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSK 230 Query: 308 ----IVGIVAGLAVLAVVVI 323 I G V GL L + +I Sbjct: 231 MLSGIGGFVLGLIFLGLGLI 250 >gi|4502649 CD1D antigen precursor [Homo sapiens] Length = 335 Score = 72.8 bits (177), Expect = 5e-13 Identities = 66/219 (30%), Positives = 98/219 (44%), Gaps = 23/219 (10%) Query: 119 LQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQ--------ITQRK 170 LQ GC+V P G A+ GKD ++ SW A + Q K Sbjct: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170 Query: 171 WEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPI-SDHEATLRCWA 229 W RE Q L G C +++ LE+GK +L++ PK ++ P L C Sbjct: 171 W--TRETVQW--LLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHV 226 Query: 230 LGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEG 289 GFYP + + W R GE + Q T+ + P D T+ A + V +GE +C V+H Sbjct: 227 SGFYPKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285 Query: 290 LP-KPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVV 327 L + + L W S S +G++A LAVLA ++ +V Sbjct: 286 LEGQDIVLYWGGSYTS----MGLIA-LAVLACLLFLLIV 319 >gi|239740920 PREDICTED: similar to major histocompatibility complex, class II, DQ beta 1 isoform 2 [Homo sapiens] Length = 261 Score = 72.0 bits (175), Expect = 8e-13 Identities = 53/200 (26%), Positives = 83/200 (41%), Gaps = 15/200 (7%) Query: 134 LRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREA-EQRRAYLEGECVE-- 190 +RG +Y Y+ ++Y + D+ + A W + +E E+ RA L+ C Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNY 115 Query: 191 --WLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ 248 LR L+ + P +T +H L C FYPA+I + W R+ +++ Sbjct: 116 QLELRTTLQRRVEPTVTISPSRTEALNH-----HNLLVCSVTDFYPAQIKVRWFRNDQEE 170 Query: 249 TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVP- 307 T GD TFQ + + YTCHV+H L P+ + W S+S Sbjct: 171 TTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSK 230 Query: 308 ----IVGIVAGLAVLAVVVI 323 I G V GL L + +I Sbjct: 231 MLSGIGGFVLGLIFLGLGLI 250 >gi|24797076 major histocompatibility complex, class II, DP beta 1 precursor [Homo sapiens] Length = 258 Score = 70.9 bits (172), Expect = 2e-12 Identities = 52/210 (24%), Positives = 90/210 (42%), Gaps = 10/210 (4%) Query: 138 DQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREA-EQRRAYLEGECVEWLRRYL 196 ++Y Y+ +++ + D+ + A + W + ++ E++RA + C Y Sbjct: 55 ERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMC---RHNYE 111 Query: 197 ENGKDKLERADPPKTHVTHH---PISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTE 253 G L+R P+ +V+ P+ H L C FYP I + W +G+++T Sbjct: 112 LGGPMTLQRRVQPRVNVSPSKKGPLQHHNL-LVCHVTDFYPGSIQVRWFLNGQEETAGVV 170 Query: 254 LVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVA 313 GD TFQ + + + YTC V+H L P+T+ W+ S S A Sbjct: 171 STNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGA 230 Query: 314 GLAVLAVVVIGAVVAAVMCRRKSSGGKGGS 343 G VL +++ G V M RR +G + Sbjct: 231 GGFVLGLIICG--VGIFMHRRSKKVQRGSA 258 >gi|110618224 CD1A antigen precursor [Homo sapiens] Length = 327 Score = 70.9 bits (172), Expect = 2e-12 Identities = 66/284 (23%), Positives = 116/284 (40%), Gaps = 31/284 (10%) Query: 50 GYVDDTQFVRFDSDAASPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGY 108 G++ D Q +DS++++ PW E W +++ + E +R Sbjct: 47 GWLSDLQTHTWDSNSSTIVF--LCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRY--- 101 Query: 109 YNQSEAGSHTLQSMY--------GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAA 160 +H LQ Y GC++ G++ Q AY G D+++ + SW Sbjct: 102 -------AHELQFEYPFEIQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPY 151 Query: 161 DTAAQITQRKWEAAREAEQRRAY----LEGECVEWLRRYLENGKDKLERADPPKTHVTHH 216 A + + + + + L C ++ L+ GK L+R P+ ++H Sbjct: 152 PVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHG 211 Query: 217 PI-SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS 275 P L C GFYP + + W R GE + Q T+ + P+ D T+ A + V + Sbjct: 212 PSPGPGHLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAA 270 Query: 276 GEEQRYTCHVQHEGLP-KPLTLRWEPSSQSTVPIVGIVAGLAVL 318 GE +C V+H L + + L WE S I+ ++ L +L Sbjct: 271 GEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLL 314 >gi|239758095 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 [Homo sapiens] Length = 281 Score = 70.5 bits (171), Expect = 2e-12 Identities = 55/222 (24%), Positives = 93/222 (41%), Gaps = 20/222 (9%) Query: 142 YDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREA-EQRRAYLEGECVE----WLRRYL 196 Y+ ++ + + D+ + A W + ++ E++RA ++ C LR L Sbjct: 64 YNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTL 123 Query: 197 ENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVE 256 + + P +T +H L C FYPA+I + W R+G+++T Sbjct: 124 QRRVEPTVTISPSRTEALNH-----HNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTP 178 Query: 257 TRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVP-----IVGI 311 GD TFQ + + YTCHV+H L P+T+ W S+S I G Sbjct: 179 LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGF 238 Query: 312 VAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY--SQAACSD 351 V GL L +G ++ + + GK G + +Q CS+ Sbjct: 239 VLGLIFLG---LGLIIHHRSQKGEEPQGKRGRWPVTQTLCSE 277 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.131 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,057,919 Number of Sequences: 37866 Number of extensions: 705617 Number of successful extensions: 2242 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 93 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 1991 Number of HSP's gapped (non-prelim): 192 length of query: 362 length of database: 18,247,518 effective HSP length: 104 effective length of query: 258 effective length of database: 14,309,454 effective search space: 3691839132 effective search space used: 3691839132 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.