Guide to the Human Genome
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Name: HFE Sequence: fasta or formatted (260aa) NCBI GI: 21040349
Description:

hemochromatosis protein isoform 7 precursor

Referenced in:

HLA and Related Proteins
Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [242aa] hemochromatosis protein isoform 3 precursor
alt prot [256aa] hemochromatosis protein isoform 4 precursor
alt prot [334aa] hemochromatosis protein isoform 6 precursor
alt prot [246aa] hemochromatosis protein isoform 8 precursor
alt prot [325aa] hemochromatosis protein isoform 9 precursor
alt prot [168aa] hemochromatosis protein isoform 10 precursor
alt prot [76aa] hemochromatosis protein isoform 11 precursor
alt prot [348aa] hemochromatosis protein isoform 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8         15           2
 C cysteine            1.9          5           1
 D aspartate           4.6         12           1
 E glutamate           6.5         17           2
 F phenylalanine       1.9          5           1
 G glycine             7.7         20           1
 H histidine           2.7          7           2
 I isoleucine          5.4         14           2
 K lysine              3.8         10           1
 L leucine            12.7         33           4
 M methionine          2.3          6           1
 N asparagine          1.9          5           1
 P proline             6.9         18           2
 Q glutamine           7.3         19           2
 R arginine            6.9         18           1
 S serine              3.1          8           2
 T threonine           5.4         14           2
 V valine              6.9         18           2
 W tryptophan          2.7          7           1
 Y tyrosine            3.5          9           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemochromatosis protein isoform 7 precursor 
HFE                   0.926   hemochromatosis protein isoform 8 precursor 
HFE                   0.909   hemochromatosis protein isoform 9 precursor 
HFE                   0.909   hemochromatosis protein isoform 1 precursor 
HFE                   0.837   hemochromatosis protein isoform 6 precursor 
HFE                   0.610   hemochromatosis protein isoform 4 precursor 
HFE                   0.555   hemochromatosis protein isoform 3 precursor 
HFE                   0.524   hemochromatosis protein isoform 10 precursor 
HLA-B                 0.295   major histocompatibility complex, class I, B precurs...
HLA-F                 0.274   major histocompatibility complex, class I, F isofor...
HLA-F                 0.274   major histocompatibility complex, class I, F isofor...
HLA-C                 0.274   major histocompatibility complex, class I, C precurs...
LOC652614             0.274   PREDICTED: similar to MHC class I antigen 
HLA-A                 0.268   major histocompatibility complex, class I, A precurs...
HLA-G                 0.260   major histocompatibility complex, class I, G precurso...
MR1                   0.256   major histocompatibility complex, class I-related [Ho...
AZGP1                 0.256   alpha-2-glycoprotein 1, zinc 
HLA-E                 0.252   major histocompatibility complex, class I, E precurs...
MICA                  0.179   MHC class I polypeptide-related sequence A 
MICB                  0.171   MHC class I polypeptide-related sequence B 
FCGRT                 0.163   Fc fragment of IgG, receptor, transporter, alpha [H...
FCGRT                 0.163   Fc fragment of IgG, receptor, transporter, alpha [Hom...
HFE                   0.144   hemochromatosis protein isoform 11 precursor 
LOC100294318          0.132   PREDICTED: similar to major histocompatibility comp...
LOC100294318          0.132   PREDICTED: similar to major histocompatibility comp...
LOC100133583          0.124   PREDICTED: similar to major histocompatibility comp...
HLA-DQB1              0.118   major histocompatibility complex, class II, DQ beta...
LOC100294278          0.117   PREDICTED: similar to major histocompatibility comp...
LOC100294115          0.117   PREDICTED: similar to major histocompatibility comp...
LOC100293977          0.117   PREDICTED: similar to major histocompatibility comp...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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