Guide to the Human Genome
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Name: HFE Sequence: fasta or formatted (168aa) NCBI GI: 21040355
Description:

hemochromatosis protein isoform 10 precursor

Referenced in:

HLA and Related Proteins
Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [242aa] hemochromatosis protein isoform 3 precursor
alt prot [256aa] hemochromatosis protein isoform 4 precursor
alt prot [334aa] hemochromatosis protein isoform 6 precursor
alt prot [260aa] hemochromatosis protein isoform 7 precursor
alt prot [246aa] hemochromatosis protein isoform 8 precursor
alt prot [325aa] hemochromatosis protein isoform 9 precursor
alt prot [76aa] hemochromatosis protein isoform 11 precursor
alt prot [348aa] hemochromatosis protein isoform 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.4          9           1
 C cysteine            1.2          2           1
 D aspartate           3.0          5           1
 E glutamate           4.8          8           2
 F phenylalanine       2.4          4           1
 G glycine             8.3         14           1
 H histidine           2.4          4           2
 I isoleucine          7.1         12           2
 K lysine              4.2          7           1
 L leucine            13.7         23           4
 M methionine          3.0          5           1
 N asparagine          1.8          3           1
 P proline             8.3         14           2
 Q glutamine           5.4          9           1
 R arginine            6.0         10           1
 S serine              3.6          6           2
 T threonine           6.0         10           2
 V valine              8.9         15           2
 W tryptophan          1.8          3           1
 Y tyrosine            3.0          5           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemochromatosis protein isoform 10 precursor 
HFE                   0.852   hemochromatosis protein isoform 9 precursor 
HFE                   0.852   hemochromatosis protein isoform 7 precursor 
HFE                   0.852   hemochromatosis protein isoform 4 precursor 
HFE                   0.852   hemochromatosis protein isoform 1 precursor 
HFE                   0.776   hemochromatosis protein isoform 3 precursor 
HFE                   0.767   hemochromatosis protein isoform 8 precursor 
HFE                   0.767   hemochromatosis protein isoform 6 precursor 
LOC652614             0.297   PREDICTED: similar to MHC class I antigen 
HLA-B                 0.293   major histocompatibility complex, class I, B precurs...
HLA-C                 0.290   major histocompatibility complex, class I, C precurs...
HLA-F                 0.287   major histocompatibility complex, class I, F isofor...
HLA-F                 0.287   major histocompatibility complex, class I, F isofor...
HLA-E                 0.268   major histocompatibility complex, class I, E precurs...
HLA-A                 0.262   major histocompatibility complex, class I, A precurs...
HLA-G                 0.243   major histocompatibility complex, class I, G precurso...
HFE                   0.233   hemochromatosis protein isoform 11 precursor 
MICA                  0.196   MHC class I polypeptide-related sequence A 
MR1                   0.192   major histocompatibility complex, class I-related [Ho...
MICB                  0.183   MHC class I polypeptide-related sequence B 
AZGP1                 0.170   alpha-2-glycoprotein 1, zinc 
LOC100294036          0.132   PREDICTED: similar to HLA class II histocompatibili...
LOC100294275          0.132   PREDICTED: similar to major histocompatibility comp...
LOC100294275          0.132   PREDICTED: similar to major histocompatibility comp...
HLA-DRB5              0.132   major histocompatibility complex, class II, DR beta ...
HLA-DRB4              0.132   major histocompatibility complex, class II, DR beta ...
HLA-DRB4              0.132   PREDICTED: major histocompatibility complex, class ...
LOC100294468          0.132   PREDICTED: similar to HLA class II histocompatibili...
LOC100294189          0.132   PREDICTED: similar to HLA class II histocompatibili...
LOC100294189          0.132   PREDICTED: similar to HLA class II histocompatibili...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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