Guide to the Human Genome
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Name: MICA Sequence: fasta or formatted (383aa) NCBI GI: 4557751
Description:

MHC class I polypeptide-related sequence A

Referenced in:

HLA and Related Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         25           4
 C cysteine            2.3          9           2
 D aspartate           5.2         20           1
 E glutamate           5.5         21           2
 F phenylalanine       3.7         14           1
 G glycine             7.6         29           1
 H histidine           4.4         17           1
 I isoleucine          2.9         11           3
 K lysine              3.9         15           3
 L leucine             9.4         36           3
 M methionine          2.3          9           1
 N asparagine          3.1         12           1
 P proline             4.4         17           2
 Q glutamine           6.3         24           2
 R arginine            5.7         22           2
 S serine              7.6         29           2
 T threonine           7.6         29           1
 V valine              6.8         26           2
 W tryptophan          2.3          9           1
 Y tyrosine            2.3          9           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   MHC class I polypeptide-related sequence A 
MICB                  0.791   MHC class I polypeptide-related sequence B 
HLA-C                 0.153   major histocompatibility complex, class I, C precurs...
HLA-E                 0.152   major histocompatibility complex, class I, E precurs...
HLA-A                 0.152   major histocompatibility complex, class I, A precurs...
HLA-F                 0.149   major histocompatibility complex, class I, F isofor...
HLA-F                 0.149   major histocompatibility complex, class I, F isofor...
HLA-B                 0.149   major histocompatibility complex, class I, B precurs...
LOC652614             0.149   PREDICTED: similar to MHC class I antigen 
HFE                   0.141   hemochromatosis protein isoform 1 precursor 
HLA-G                 0.141   major histocompatibility complex, class I, G precurso...
MR1                   0.137   major histocompatibility complex, class I-related [Ho...
HFE                   0.136   hemochromatosis protein isoform 9 precursor 
HFE                   0.123   hemochromatosis protein isoform 6 precursor 
HFE                   0.119   hemochromatosis protein isoform 7 precursor 
HFE                   0.101   hemochromatosis protein isoform 8 precursor 
AZGP1                 0.095   alpha-2-glycoprotein 1, zinc 
HFE                   0.082   hemochromatosis protein isoform 4 precursor 
HFE                   0.080   hemochromatosis protein isoform 10 precursor 
FCGRT                 0.077   Fc fragment of IgG, receptor, transporter, alpha [H...
FCGRT                 0.077   Fc fragment of IgG, receptor, transporter, alpha [Hom...
HFE                   0.071   hemochromatosis protein isoform 3 precursor 
HLA-F                 0.058   major histocompatibility complex, class I, F isofor...
CD1D                  0.052   CD1D antigen precursor 
CD1C                  0.044   CD1C antigen precursor 
CD1A                  0.040   CD1A antigen precursor 
RAET1E                0.039   retinoic acid early transcript 1E 
HLA-DMB               0.038   major histocompatibility complex, class II, DM beta p...
ULBP3                 0.038   UL16 binding protein 3 
SIRPB1                0.034   signal-regulatory protein beta 1 isoform 1 precurso...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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