Guide to the Human Genome
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Name: HLA-C Sequence: fasta or formatted (366aa) NCBI GI: 52630342
Description:

major histocompatibility complex, class I, C precursor

Referenced in:

HLA and Related Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.1         37           2
 C cysteine            2.5          9           1
 D aspartate           5.7         21           2
 E glutamate           7.1         26           1
 F phenylalanine       1.6          6           1
 G glycine             8.2         30           2
 H histidine           2.2          8           2
 I isoleucine          2.2          8           1
 K lysine              2.7         10           1
 L leucine             9.3         34           5
 M methionine          2.2          8           2
 N asparagine          1.4          5           1
 P proline             4.9         18           2
 Q glutamine           6.3         23           1
 R arginine            8.2         30           2
 S serine              7.1         26           2
 T threonine           6.8         25           1
 V valine              5.5         20           3
 W tryptophan          2.5          9           1
 Y tyrosine            3.6         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   major histocompatibility complex, class I, C precurs... 
HLA-B                 0.846   major histocompatibility complex, class I, B precurs...
HLA-A                 0.804   major histocompatibility complex, class I, A precurs...
HLA-G                 0.734   major histocompatibility complex, class I, G precurso...
HLA-E                 0.732   major histocompatibility complex, class I, E precurs...
HLA-F                 0.723   major histocompatibility complex, class I, F isofor...
HLA-F                 0.720   major histocompatibility complex, class I, F isofor...
LOC652614             0.644   PREDICTED: similar to MHC class I antigen 
HLA-F                 0.407   major histocompatibility complex, class I, F isofor...
MR1                   0.273   major histocompatibility complex, class I-related [Ho...
HFE                   0.249   hemochromatosis protein isoform 1 precursor 
HFE                   0.232   hemochromatosis protein isoform 9 precursor 
HFE                   0.223   hemochromatosis protein isoform 6 precursor 
AZGP1                 0.217   alpha-2-glycoprotein 1, zinc 
HFE                   0.194   hemochromatosis protein isoform 7 precursor 
HFE                   0.169   hemochromatosis protein isoform 8 precursor 
MICA                  0.162   MHC class I polypeptide-related sequence A 
FCGRT                 0.159   Fc fragment of IgG, receptor, transporter, alpha [H...
FCGRT                 0.159   Fc fragment of IgG, receptor, transporter, alpha [Hom...
MICB                  0.155   MHC class I polypeptide-related sequence B 
HFE                   0.126   hemochromatosis protein isoform 10 precursor 
HFE                   0.126   hemochromatosis protein isoform 4 precursor 
HFE                   0.114   hemochromatosis protein isoform 3 precursor 
CD1A                  0.080   CD1A antigen precursor 
CD1D                  0.066   CD1D antigen precursor 
CD1B                  0.066   CD1B antigen precursor 
LOC100293977          0.062   PREDICTED: similar to major histocompatibility comp...
LOC100294191          0.062   PREDICTED: similar to major histocompatibility comp...
LOC100294318          0.060   PREDICTED: similar to major histocompatibility comp...
HLA-DMB               0.058   major histocompatibility complex, class II, DM beta p...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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