Guide to the Human Genome
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Name: HFE Sequence: fasta or formatted (325aa) NCBI GI: 21040353
Description:

hemochromatosis protein isoform 9 precursor

Referenced in:

HLA and Related Proteins
Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [242aa] hemochromatosis protein isoform 3 precursor
alt prot [256aa] hemochromatosis protein isoform 4 precursor
alt prot [334aa] hemochromatosis protein isoform 6 precursor
alt prot [260aa] hemochromatosis protein isoform 7 precursor
alt prot [246aa] hemochromatosis protein isoform 8 precursor
alt prot [168aa] hemochromatosis protein isoform 10 precursor
alt prot [76aa] hemochromatosis protein isoform 11 precursor
alt prot [348aa] hemochromatosis protein isoform 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.6         15           2
 C cysteine            1.5          5           1
 D aspartate           5.2         17           2
 E glutamate           6.5         21           2
 F phenylalanine       2.8          9           1
 G glycine             6.8         22           1
 H histidine           3.4         11           2
 I isoleucine          4.9         16           2
 K lysine              3.7         12           1
 L leucine            11.7         38           4
 M methionine          2.8          9           1
 N asparagine          2.2          7           1
 P proline             6.5         21           2
 Q glutamine           6.8         22           2
 R arginine            6.8         22           2
 S serine              4.9         16           2
 T threonine           5.2         17           2
 V valine              7.1         23           2
 W tryptophan          3.4         11           1
 Y tyrosine            3.4         11           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemochromatosis protein isoform 9 precursor 
HFE                   0.976   hemochromatosis protein isoform 1 precursor 
HFE                   0.918   hemochromatosis protein isoform 6 precursor 
HFE                   0.715   hemochromatosis protein isoform 7 precursor 
HFE                   0.658   hemochromatosis protein isoform 8 precursor 
HFE                   0.415   hemochromatosis protein isoform 4 precursor 
HFE                   0.412   hemochromatosis protein isoform 10 precursor 
HFE                   0.376   hemochromatosis protein isoform 3 precursor 
MR1                   0.278   major histocompatibility complex, class I-related [Ho...
HLA-B                 0.269   major histocompatibility complex, class I, B precurs...
HLA-A                 0.266   major histocompatibility complex, class I, A precurs...
LOC652614             0.263   PREDICTED: similar to MHC class I antigen 
HLA-C                 0.258   major histocompatibility complex, class I, C precurs...
HLA-G                 0.253   major histocompatibility complex, class I, G precurso...
HLA-F                 0.250   major histocompatibility complex, class I, F isofor...
HLA-F                 0.250   major histocompatibility complex, class I, F isofor...
HLA-E                 0.249   major histocompatibility complex, class I, E precurs...
AZGP1                 0.234   alpha-2-glycoprotein 1, zinc 
MICB                  0.171   MHC class I polypeptide-related sequence B 
MICA                  0.160   MHC class I polypeptide-related sequence A 
FCGRT                 0.144   Fc fragment of IgG, receptor, transporter, alpha [H...
FCGRT                 0.144   Fc fragment of IgG, receptor, transporter, alpha [Hom...
HFE                   0.113   hemochromatosis protein isoform 11 precursor 
LOC100294318          0.096   PREDICTED: similar to major histocompatibility comp...
CD1D                  0.096   CD1D antigen precursor 
LOC100294318          0.096   PREDICTED: similar to major histocompatibility comp...
HLA-DQB1              0.093   major histocompatibility complex, class II, DQ beta...
LOC100133583          0.092   PREDICTED: similar to major histocompatibility comp...
LOC100133583          0.085   PREDICTED: similar to major histocompatibility comp...
LOC100294278          0.085   PREDICTED: similar to major histocompatibility comp...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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