Guide to the Human Genome
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Name: HLA-A Sequence: fasta or formatted (365aa) NCBI GI: 24797067
Description:

major histocompatibility complex, class I, A precursor

Referenced in:

HLA and Related Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.9         36           2
 C cysteine            1.4          5           1
 D aspartate           6.6         24           2
 E glutamate           6.3         23           2
 F phenylalanine       2.2          8           2
 G glycine             7.9         29           2
 H histidine           2.5          9           2
 I isoleucine          3.6         13           2
 K lysine              3.0         11           1
 L leucine             7.9         29           5
 M methionine          2.2          8           1
 N asparagine          1.1          4           1
 P proline             4.4         16           2
 Q glutamine           6.0         22           1
 R arginine            7.7         28           2
 S serine              6.6         24           2
 T threonine           7.9         29           1
 V valine              6.0         22           3
 W tryptophan          3.0         11           1
 Y tyrosine            3.8         14           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   major histocompatibility complex, class I, A precurs... 
HLA-B                 0.847   major histocompatibility complex, class I, B precurs...
HLA-C                 0.806   major histocompatibility complex, class I, C precurs...
HLA-G                 0.784   major histocompatibility complex, class I, G precurso...
HLA-E                 0.769   major histocompatibility complex, class I, E precurs...
HLA-F                 0.762   major histocompatibility complex, class I, F isofor...
HLA-F                 0.760   major histocompatibility complex, class I, F isofor...
LOC652614             0.652   PREDICTED: similar to MHC class I antigen 
HLA-F                 0.393   major histocompatibility complex, class I, F isofor...
MR1                   0.289   major histocompatibility complex, class I-related [Ho...
HFE                   0.263   hemochromatosis protein isoform 1 precursor 
HFE                   0.240   hemochromatosis protein isoform 9 precursor 
HFE                   0.240   hemochromatosis protein isoform 6 precursor 
AZGP1                 0.237   alpha-2-glycoprotein 1, zinc 
HFE                   0.190   hemochromatosis protein isoform 7 precursor 
HFE                   0.165   hemochromatosis protein isoform 8 precursor 
MICB                  0.161   MHC class I polypeptide-related sequence B 
MICA                  0.161   MHC class I polypeptide-related sequence A 
FCGRT                 0.157   Fc fragment of IgG, receptor, transporter, alpha [H...
FCGRT                 0.157   Fc fragment of IgG, receptor, transporter, alpha [Hom...
HFE                   0.114   hemochromatosis protein isoform 10 precursor 
HFE                   0.114   hemochromatosis protein isoform 4 precursor 
HFE                   0.103   hemochromatosis protein isoform 3 precursor 
CD1A                  0.092   CD1A antigen precursor 
LOC100133583          0.067   PREDICTED: similar to major histocompatibility comp...
LOC100294318          0.065   PREDICTED: similar to major histocompatibility comp...
LOC100294318          0.065   PREDICTED: similar to major histocompatibility comp...
HLA-DPB1              0.065   major histocompatibility complex, class II, DP beta ...
LOC100293977          0.065   PREDICTED: similar to major histocompatibility comp...
LOC100294191          0.065   PREDICTED: similar to major histocompatibility comp...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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