Guide to the Human Genome
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Name: HFE Sequence: fasta or formatted (242aa) NCBI GI: 21040341
Description:

hemochromatosis protein isoform 3 precursor

Referenced in:

HLA and Related Proteins
Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [256aa] hemochromatosis protein isoform 4 precursor
alt prot [334aa] hemochromatosis protein isoform 6 precursor
alt prot [260aa] hemochromatosis protein isoform 7 precursor
alt prot [246aa] hemochromatosis protein isoform 8 precursor
alt prot [325aa] hemochromatosis protein isoform 9 precursor
alt prot [168aa] hemochromatosis protein isoform 10 precursor
alt prot [76aa] hemochromatosis protein isoform 11 precursor
alt prot [348aa] hemochromatosis protein isoform 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.5         11           1
 C cysteine            0.8          2           1
 D aspartate           4.5         11           2
 E glutamate           5.4         13           2
 F phenylalanine       4.1         10           1
 G glycine             7.4         18           1
 H histidine           3.3          8           1
 I isoleucine          5.8         14           2
 K lysine              3.3          8           1
 L leucine            12.8         31           4
 M methionine          3.7          9           1
 N asparagine          2.1          5           1
 P proline             5.8         14           2
 Q glutamine           5.8         14           1
 R arginine            6.2         15           2
 S serine              6.6         16           2
 T threonine           4.5         11           2
 V valine              7.0         17           2
 W tryptophan          2.9          7           1
 Y tyrosine            3.3          8           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemochromatosis protein isoform 3 precursor 
HFE                   0.981   hemochromatosis protein isoform 4 precursor 
HFE                   0.605   hemochromatosis protein isoform 7 precursor 
HFE                   0.605   hemochromatosis protein isoform 8 precursor 
HFE                   0.520   hemochromatosis protein isoform 10 precursor 
HFE                   0.520   hemochromatosis protein isoform 9 precursor 
HFE                   0.520   hemochromatosis protein isoform 1 precursor 
HFE                   0.516   hemochromatosis protein isoform 6 precursor 
LOC652614             0.180   PREDICTED: similar to MHC class I antigen 
HLA-F                 0.175   major histocompatibility complex, class I, F isofor...
HLA-F                 0.175   major histocompatibility complex, class I, F isofor...
HLA-B                 0.175   major histocompatibility complex, class I, B precurs...
HLA-C                 0.175   major histocompatibility complex, class I, C precurs...
HLA-E                 0.159   major histocompatibility complex, class I, E precurs...
HLA-A                 0.159   major histocompatibility complex, class I, A precurs...
HFE                   0.156   hemochromatosis protein isoform 11 precursor 
HLA-G                 0.146   major histocompatibility complex, class I, G precurso...
MICA                  0.116   MHC class I polypeptide-related sequence A 
MR1                   0.114   major histocompatibility complex, class I-related [Ho...
MICB                  0.106   MHC class I polypeptide-related sequence B 
AZGP1                 0.101   alpha-2-glycoprotein 1, zinc 
LOC100294275          0.091   PREDICTED: similar to major histocompatibility comp...
LOC100294275          0.091   PREDICTED: similar to major histocompatibility comp...
HLA-DRB5              0.091   major histocompatibility complex, class II, DR beta ...
HLA-DRB4              0.089   major histocompatibility complex, class II, DR beta ...
LOC100294036          0.089   PREDICTED: similar to HLA class II histocompatibili...
HLA-DRB4              0.089   PREDICTED: major histocompatibility complex, class ...
LOC100294468          0.089   PREDICTED: similar to HLA class II histocompatibili...
LOC100294189          0.089   PREDICTED: similar to HLA class II histocompatibili...
LOC100294189          0.089   PREDICTED: similar to HLA class II histocompatibili...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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