Guide to the Human Genome
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Name: HFE Sequence: fasta or formatted (256aa) NCBI GI: 21040343
Description:

hemochromatosis protein isoform 4 precursor

Referenced in:

HLA and Related Proteins
Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [242aa] hemochromatosis protein isoform 3 precursor
alt prot [334aa] hemochromatosis protein isoform 6 precursor
alt prot [260aa] hemochromatosis protein isoform 7 precursor
alt prot [246aa] hemochromatosis protein isoform 8 precursor
alt prot [325aa] hemochromatosis protein isoform 9 precursor
alt prot [168aa] hemochromatosis protein isoform 10 precursor
alt prot [76aa] hemochromatosis protein isoform 11 precursor
alt prot [348aa] hemochromatosis protein isoform 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.3         11           1
 C cysteine            0.8          2           1
 D aspartate           4.3         11           2
 E glutamate           5.1         13           2
 F phenylalanine       3.9         10           1
 G glycine             7.0         18           1
 H histidine           3.9         10           2
 I isoleucine          5.5         14           2
 K lysine              3.5          9           1
 L leucine            12.5         32           4
 M methionine          3.5          9           1
 N asparagine          2.0          5           1
 P proline             6.2         16           2
 Q glutamine           5.5         14           1
 R arginine            5.9         15           2
 S serine              7.0         18           2
 T threonine           5.1         13           2
 V valine              8.2         21           2
 W tryptophan          2.7          7           1
 Y tyrosine            3.1          8           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemochromatosis protein isoform 4 precursor 
HFE                   0.926   hemochromatosis protein isoform 3 precursor 
HFE                   0.627   hemochromatosis protein isoform 7 precursor 
HFE                   0.567   hemochromatosis protein isoform 8 precursor 
HFE                   0.543   hemochromatosis protein isoform 9 precursor 
HFE                   0.543   hemochromatosis protein isoform 1 precursor 
HFE                   0.539   hemochromatosis protein isoform 10 precursor 
HFE                   0.485   hemochromatosis protein isoform 6 precursor 
LOC652614             0.188   PREDICTED: similar to MHC class I antigen 
HLA-B                 0.186   major histocompatibility complex, class I, B precurs...
HLA-C                 0.184   major histocompatibility complex, class I, C precurs...
HLA-F                 0.182   major histocompatibility complex, class I, F isofor...
HLA-F                 0.182   major histocompatibility complex, class I, F isofor...
HLA-E                 0.170   major histocompatibility complex, class I, E precurs...
HLA-A                 0.166   major histocompatibility complex, class I, A precurs...
HLA-G                 0.154   major histocompatibility complex, class I, G precurso...
HFE                   0.148   hemochromatosis protein isoform 11 precursor 
MICA                  0.126   MHC class I polypeptide-related sequence A 
MR1                   0.122   major histocompatibility complex, class I-related [Ho...
MICB                  0.116   MHC class I polypeptide-related sequence B 
AZGP1                 0.108   alpha-2-glycoprotein 1, zinc 
HLA-DMB               0.092   major histocompatibility complex, class II, DM beta p...
LOC100294318          0.088   PREDICTED: similar to major histocompatibility comp...
LOC100294318          0.088   PREDICTED: similar to major histocompatibility comp...
LOC100133583          0.086   PREDICTED: similar to major histocompatibility comp...
HLA-DRB4              0.086   major histocompatibility complex, class II, DR beta ...
HLA-DRB4              0.086   PREDICTED: major histocompatibility complex, class ...
LOC100290966          0.084   PREDICTED: hypothetical protein XP_002346811 
LOC100294276          0.084   PREDICTED: similar to major histocompatibility comp...
LOC100294276          0.084   PREDICTED: similar to major histocompatibility comp...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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