Guide to the Human Genome
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Name: HLA-E Sequence: fasta or formatted (358aa) NCBI GI: 62912479
Description:

major histocompatibility complex, class I, E precursor

Referenced in:

HLA and Related Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.1         29           2
 C cysteine            1.1          4           1
 D aspartate           5.3         19           2
 E glutamate           8.1         29           2
 F phenylalanine       2.5          9           1
 G glycine             8.4         30           2
 H histidine           4.2         15           2
 I isoleucine          2.8         10           2
 K lysine              3.6         13           2
 L leucine             8.9         32           5
 M methionine          1.1          4           1
 N asparagine          1.4          5           1
 P proline             4.7         17           2
 Q glutamine           5.0         18           2
 R arginine            5.9         21           1
 S serine              8.1         29           2
 T threonine           7.3         26           1
 V valine              6.4         23           3
 W tryptophan          3.4         12           1
 Y tyrosine            3.6         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   major histocompatibility complex, class I, E precurs... 
HLA-A                 0.775   major histocompatibility complex, class I, A precurs...
HLA-B                 0.764   major histocompatibility complex, class I, B precurs...
HLA-C                 0.740   major histocompatibility complex, class I, C precurs...
HLA-G                 0.728   major histocompatibility complex, class I, G precurso...
HLA-F                 0.688   major histocompatibility complex, class I, F isofor...
HLA-F                 0.688   major histocompatibility complex, class I, F isofor...
LOC652614             0.635   PREDICTED: similar to MHC class I antigen 
HLA-F                 0.344   major histocompatibility complex, class I, F isofor...
MR1                   0.278   major histocompatibility complex, class I-related [Ho...
HFE                   0.244   hemochromatosis protein isoform 1 precursor 
HFE                   0.226   hemochromatosis protein isoform 9 precursor 
HFE                   0.221   hemochromatosis protein isoform 6 precursor 
AZGP1                 0.212   alpha-2-glycoprotein 1, zinc 
HFE                   0.181   hemochromatosis protein isoform 7 precursor 
FCGRT                 0.165   Fc fragment of IgG, receptor, transporter, alpha [H...
FCGRT                 0.165   Fc fragment of IgG, receptor, transporter, alpha [Hom...
MICA                  0.163   MHC class I polypeptide-related sequence A 
MICB                  0.161   MHC class I polypeptide-related sequence B 
HFE                   0.157   hemochromatosis protein isoform 8 precursor 
HFE                   0.118   hemochromatosis protein isoform 10 precursor 
HFE                   0.118   hemochromatosis protein isoform 4 precursor 
HFE                   0.104   hemochromatosis protein isoform 3 precursor 
CD1A                  0.085   CD1A antigen precursor 
LOC100133583          0.065   PREDICTED: similar to major histocompatibility comp...
LOC100294318          0.062   PREDICTED: similar to major histocompatibility comp...
LOC100294318          0.062   PREDICTED: similar to major histocompatibility comp...
HLA-DMB               0.061   major histocompatibility complex, class II, DM beta p...
HLA-DPB1              0.058   major histocompatibility complex, class II, DP beta ...
HLA-DQB1              0.058   major histocompatibility complex, class II, DQ beta...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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