Guide to the Human Genome
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Search of human proteins with 17738302

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
         (744 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]      1626   0.0  
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]      1626   0.0  
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]               745   0.0  
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          704   0.0  
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   478   e-135
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   475   e-134
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   473   e-133
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    456   e-128
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      447   e-125
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   441   e-124
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   441   e-124
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   441   e-124
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   431   e-121
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   431   e-120
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   431   e-120
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     429   e-120
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               427   e-119
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     426   e-119
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     426   e-119
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      425   e-119
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              421   e-117
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        419   e-117
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   419   e-117
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   419   e-117
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   419   e-117
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   418   e-116
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   418   e-116
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   418   e-116
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         417   e-116
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       417   e-116

>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 1626 bits (4211), Expect = 0.0
 Identities = 744/744 (100%), Positives = 744/744 (100%)

Query: 1   MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH 60
           MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH
Sbjct: 1   MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH 60

Query: 61  MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ 120
           MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ
Sbjct: 61  MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ 120

Query: 121 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180
           GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE
Sbjct: 121 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180

Query: 181 IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK 240
           IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK
Sbjct: 181 IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK 240

Query: 241 GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP 300
           GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP
Sbjct: 241 GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP 300

Query: 301 IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360
           IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG
Sbjct: 301 IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360

Query: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420
           DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG
Sbjct: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420

Query: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
           PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG
Sbjct: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480

Query: 481 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540
           PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL
Sbjct: 481 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540

Query: 541 HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA 600
           HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA
Sbjct: 541 HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA 600

Query: 601 YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV 660
           YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV
Sbjct: 601 YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV 660

Query: 661 YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS 720
           YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS
Sbjct: 661 YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS 720

Query: 721 EQAAGLYAGQYVHSSFSGYLLYPM 744
           EQAAGLYAGQYVHSSFSGYLLYPM
Sbjct: 721 EQAAGLYAGQYVHSSFSGYLLYPM 744


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 1626 bits (4211), Expect = 0.0
 Identities = 744/744 (100%), Positives = 744/744 (100%)

Query: 1   MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH 60
           MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH
Sbjct: 1   MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPH 60

Query: 61  MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ 120
           MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ
Sbjct: 61  MPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQ 120

Query: 121 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180
           GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE
Sbjct: 121 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180

Query: 181 IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK 240
           IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK
Sbjct: 181 IGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPK 240

Query: 241 GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP 300
           GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP
Sbjct: 241 GDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGP 300

Query: 301 IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360
           IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG
Sbjct: 301 IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360

Query: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420
           DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG
Sbjct: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420

Query: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
           PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG
Sbjct: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480

Query: 481 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540
           PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL
Sbjct: 481 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540

Query: 541 HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA 600
           HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA
Sbjct: 541 HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA 600

Query: 601 YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV 660
           YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV
Sbjct: 601 YGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGV 660

Query: 661 YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS 720
           YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS
Sbjct: 661 YYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPS 720

Query: 721 EQAAGLYAGQYVHSSFSGYLLYPM 744
           EQAAGLYAGQYVHSSFSGYLLYPM
Sbjct: 721 EQAAGLYAGQYVHSSFSGYLLYPM 744


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score =  745 bits (1924), Expect = 0.0
 Identities = 384/678 (56%), Positives = 441/678 (65%), Gaps = 39/678 (5%)

Query: 88  QYMKEIQPAPRMGKEAVPKKGK--EIPLA----SLRGEQGPRGEPGPRGPPGPPGLPGH- 140
           +Y++ +Q  P +G      KG+  E+PL      L+GE GP G+PGPRGPPGPPG PG  
Sbjct: 42  KYIQPMQKGP-VGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKP 100

Query: 141 --GIPGIKGKPGPQGYPG---VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP 195
             G PG+ G+PGP G PG   +GK G PG+PGK G  G PG +GE G +G+ G  G PGP
Sbjct: 101 GMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160

Query: 196 QGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKG 255
            G PGP G+   GKPG  G+PG PG +G+ GP+G PGP G RG KGD G G PG PG  G
Sbjct: 161 PGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPG 220

Query: 256 PPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI 315
             G  GPPG  G  G+GKPG+ G PG  G  G+ G PG PGP+G  G  G +GPPG+ G+
Sbjct: 221 QGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV 280

Query: 316 GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRG 375
           G PG  G+PG  G  G KGE G  G PG  G  G G PG PGPKGDRG  GVPG LG RG
Sbjct: 281 GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRG 340

Query: 376 EKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQG 435
           E G  G PG  GP G  G PG+PG  G PG  G PGPKGE G  GP G PG +G+ G  G
Sbjct: 341 EPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG 400

Query: 436 FPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQG 495
             GKPG  GE G PG  G PGP GPKGE G  G PG PGV G LG KG+ G+PG  GL+G
Sbjct: 401 LAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRG 460

Query: 496 PPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQ 555
           P GIPG+ GP+GPIGP G+PG KGEPGLPGPPG    G+PG AG  GPPG PG+      
Sbjct: 461 PSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGS------ 514

Query: 556 PGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPH--AYGAKKGKNGGP-- 611
           PG+ GPPGPPGPPGPP      P    E       GI G+  P+    GA  GK G P  
Sbjct: 515 PGITGPPGPPGPPGPPG----APGAFDE------TGIAGLHLPNGGVEGAVLGKGGKPQF 564

Query: 612 ------AYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAY 665
                 A+  PAFTA LT+PFP  G PVKF++ LYNG   YNP TGIFTC V GVYYFAY
Sbjct: 565 GLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAY 624

Query: 666 HVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAG 725
           HVH KG NVWVAL+KNN P  YTYDEYKKG+LDQASG AVL LRP D+V++QMPS+QA G
Sbjct: 625 HVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANG 684

Query: 726 LYAGQYVHSSFSGYLLYP 743
           LY+ +Y+HSSFSG+LL P
Sbjct: 685 LYSTEYIHSSFSGFLLCP 702



 Score =  188 bits (478), Expect = 1e-47
 Identities = 126/278 (45%), Positives = 143/278 (51%), Gaps = 43/278 (15%)

Query: 372 GPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIG------FPGP------KGEGGIV 419
           GPR   G       G  P +   P   GP+GPP   G       P P      KGE    
Sbjct: 23  GPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGE---P 79

Query: 420 GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGP-----KGEAGQKGVPGLPG 474
           GP G PGP+G PG  GFPGKPG    +G PG+ G PGP GP      G+AG  G+PG  G
Sbjct: 80  GPPGKPGPRGPPGPPGFPGKPG----MGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVG 135

Query: 475 VPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK 534
            PG  G +GEPGI GDQGL+GPPG PG+ GPSG      IPG  G  G+PGPPGF   G+
Sbjct: 136 PPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGIT----IPGKPGAQGVPGPPGFQ--GE 189

Query: 535 PGVAGLHGPPGKPGALGPQ--GQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGI 592
           PG  G  GPPG  G  G    GQPGLPG PG  G PGPP +    P P G   P    G+
Sbjct: 190 PGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGL----PGPAGLGKP----GL 241

Query: 593 DGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVG 630
           DG+  P A G  KG++G P    P        P  P G
Sbjct: 242 DGL--PGAPG-DKGESGPPGVPGPRGEPGAVGPKGPPG 276



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 44/129 (34%), Positives = 54/129 (41%), Gaps = 12/129 (9%)

Query: 67  GLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK--EIPLASLRGEQGPRG 124
           GL     +P LQ G   P  PQ +  ++  P  G    P +G+  E   A   G  G  G
Sbjct: 457 GLRGPSGIPGLQ-GPAGPIGPQGLPGLKGEP--GLPGPPGEGRAGEPGTAGPTGPPGVPG 513

Query: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQK 184
            PG  GPPGPPG PG   PG  G     G  G+  P      G  GA+   G K + G  
Sbjct: 514 SPGITGPPGPPGPPGP--PGAPGAFDETGIAGLHLPN----GGVEGAVLGKGGKPQFG-L 566

Query: 185 GEIGPMGIP 193
           GE+     P
Sbjct: 567 GELSAHATP 575


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  704 bits (1818), Expect = 0.0
 Identities = 355/648 (54%), Positives = 422/648 (65%), Gaps = 39/648 (6%)

Query: 115 SLRGEQGPRGEPGPRGP------PGPPGLPGHGIPGIKGKPGPQGYPG---VGKPGMPGM 165
           ++RGEQG  G PGP GP       GPPG PG+G PG++G+PG  G PG   VGKPG+PG+
Sbjct: 54  AVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGL 113

Query: 166 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG------IGKPGGPGLPGQP 219
           PGKPG       +G  G KG++GP G+PGP+GPPGP G+PG       GKPG  G  G P
Sbjct: 114 PGKPGE------RGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAP 167

Query: 220 GPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGF 279
           GP+G  G KG PG  G+ G KG+ G+G PG PG +G PG  GP GP G PGVGK G  G 
Sbjct: 168 GPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGV 227

Query: 280 PGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP---GIPGIGKPGQDGIPGQPGFPGGKGEQ 336
           PG  G  G  G PGE    GPIG PG QGPP   G  GIGKPG  G PGQPG PG KG  
Sbjct: 228 PGQPGIKGDRGFPGE---MGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP 284

Query: 337 GLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG 396
           G PG+ GPPG PG GKPG PG KG+RG  G+PG  G +GE+GP G PG  G  G PG  G
Sbjct: 285 GAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMG 344

Query: 397 IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456
             GP G PG+ G PGPKGE G  GP G PG KGE G  G  GKPG+ G+ G  G +G PG
Sbjct: 345 PQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG 404

Query: 457 PIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG 516
             GPKG+ G  G PGLPG  G  G KG PG  G+ G +G PGIPG  GP GP G PG PG
Sbjct: 405 LPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPG 464

Query: 517 PKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPP 576
            KG+PG PGPPG  GI   G+ G  GPPG PG  G  G+PGLPGPPGPPGPPG  AVM  
Sbjct: 465 SKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG-QAVM-- 521

Query: 577 TPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFN 636
              P+G         + G        A +G  G P   + AFT  L+  +P +G P+ F+
Sbjct: 522 ---PEGFIKAGQRPSLSGTP---LVSANQGVTGMP---VSAFTVILSKAYPAIGTPIPFD 572

Query: 637 KLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGF 696
           K+LYN +Q+Y+P+TGIFTC++PG+YYF+YHVH KG +VWV L+KN  PVMYTYDEY KG+
Sbjct: 573 KILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGY 632

Query: 697 LDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM 744
           LDQASGSA++ L   D+V+LQ+P+ ++ GLY+ +YVHSSFSG+L+ PM
Sbjct: 633 LDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPM 680



 Score =  353 bits (907), Expect = 2e-97
 Identities = 218/463 (47%), Positives = 250/463 (53%), Gaps = 81/463 (17%)

Query: 95  PAPR-MGKEAVP----KKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH--------- 140
           P P  +GK  VP    K G+  P    +G+ GP G PGPRGPPGPPG+PG          
Sbjct: 100 PGPSAVGKPGVPGLPGKPGERGPYGP-KGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKP 158

Query: 141 GIPGIKGKPGPQGYPGV-GKPGMPGM-----------PGKPGAMGMPGAKGE-------- 180
           G  G  G PGP+G+PG  G PG+PGM           PG+PG  G+PG +G         
Sbjct: 159 GQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG 218

Query: 181 IGQKGEIGPMGIPG------------PQGPPGPHGLP------GIGKPGGPGLPGQPGPK 222
           +G++GE G  G PG            P GPPGP G P      GIGKPG  G PGQPG  
Sbjct: 219 VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIP 278

Query: 223 GDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGP---------PGMHGPPGPVGLPGVGK 273
              G KGLPG  G+ GP G  GFG PG PG+KG          PG  G  GP GLP  GK
Sbjct: 279 ---GTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP--GK 333

Query: 274 PGVTGFP---GPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGF 329
           PG+TG P   GPQGP G PG+ G PGP+G  G  G  G PG  G  G PG DG PG PG 
Sbjct: 334 PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGK 393

Query: 330 PGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGP 388
           PG  G +G PGLPGP G PG+ G PG PGP G  G  G+PG  G  G +G  G PG  GP
Sbjct: 394 PGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGP 453

Query: 389 PGEPGLPGIPGPMGPPGAIGFPGPKG--EGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV 446
            G PG+PG PG  G PG+ G PGP G    G+ GP GPPGP G  G  G PG PG  G  
Sbjct: 454 IGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPP 513

Query: 447 GPPGMRGLP-GPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIP 488
           GPPG   +P G I    +AGQ+  P L G P +   +G  G+P
Sbjct: 514 GPPGQAVMPEGFI----KAGQR--PSLSGTPLVSANQGVTGMP 550



 Score =  202 bits (514), Expect = 9e-52
 Identities = 138/330 (41%), Positives = 162/330 (49%), Gaps = 33/330 (10%)

Query: 32  GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMK 91
           G +  P ++ P  PP  PQ  P G++ P   + K G A     P +   K  P  P    
Sbjct: 235 GDRGFPGEMGPIGPPG-PQGPP-GERGPE-GIGKPGAAGAPGQPGIPGTKGLPGAPGIAG 291

Query: 92  EIQPAPRMGKEAVPK-KGKEIPLA-----SLRGEQGPRGEP------------GPRGPPG 133
              P P  GK  +P  KG+  P         +GEQGP G P            GP+GP G
Sbjct: 292 PPGP-PGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKG 350

Query: 134 PPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIP 193
            PG   HG+PG KG+ GP G    G PG  G  G PG+ G PG  G+ G  G  G  G+P
Sbjct: 351 IPG--SHGLPGPKGETGPAG--PAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLP 406

Query: 194 GPQGPPGPHGLPGIGKPGGP-GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG 252
           GP+G PG  G PG+  P GP G  G PG  G+ GP+G PG  G RGP G    G+PG PG
Sbjct: 407 GPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPP--GIPGFPG 464

Query: 253 VKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI 312
            KG PG  GPPGP G+   G  G TG PGP GP G  G PG PGP GP G PG    P  
Sbjct: 465 SKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMP-- 522

Query: 313 PGIGKPGQDGIPGQPGFPGGKGEQGLPGLP 342
            G  K GQ   P   G P     QG+ G+P
Sbjct: 523 EGFIKAGQR--PSLSGTPLVSANQGVTGMP 550


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  478 bits (1231), Expect = e-135
 Identities = 295/671 (43%), Positives = 337/671 (50%), Gaps = 149/671 (22%)

Query: 84   PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASL---RGEQGPRGEPGP-----------R 129
            P LP +   + P    G    P       L  L   +G+ GP G+PGP           +
Sbjct: 762  PGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQ 821

Query: 130  GPPGPPGLPG-------HGIPGIKGKPGP-----------QGYPGV-------GKPGMPG 164
            GPPGPPG+PG       HGIPG KG PGP           +G PG+       G PG PG
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 165  MPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKPGGPGLPGQPG 220
            +PGK GA G PG KGE+G    +GP G PGP G PG  G+PG+    G  G PGLPG  G
Sbjct: 882  LPGKAGASGFPGTKGEMGM---MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTG 938

Query: 221  PKGDRGPKGLPGPQG-----LRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPGVGKP 274
             KG +G  GLPGP G     L G KG+KG  G+PG PGV GP G  G PG  G PG+   
Sbjct: 939  EKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLS-- 996

Query: 275  GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----GKPGQDGIPGQPGFP 330
            G  G PGP GP G PG PG+PG  GP G+ G  G  G PG     G PG  G+PGQPG P
Sbjct: 997  GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056

Query: 331  GGKGEQG-----------LPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKG 378
            G  G++G           LPGLPGP G PG+ G PG PG KG  G  G+PG  G  G KG
Sbjct: 1057 GLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116

Query: 379  PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPG 438
              G PG  G PG PG  GI GP G PG  G PGP G GG  G  GPPG KG+PG  G PG
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG 1176

Query: 439  KPGFLGEVGPPGMRGLPGPIGPKGEAGQKG---VPGLPGVPGLLGPKGEPGIPGDQGLQG 495
              G  GE G PG  G PGP G  G +GQKG   +PG+PG PGL GPKGEPG  G  G+QG
Sbjct: 1177 PAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG 1235

Query: 496  PPGIPGIGGPS--------GPIGPPGIPGP------------------------KGEPGL 523
            PPG PG  GP+        GP GPPG PGP                        KG PG 
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ 1295

Query: 524  PGPPGFPGI----------------------------GKPGVAGLHGPPGKPGALGPQGQ 555
            PG PG PG+                            G PG  G+ GP G PG+ GP+G+
Sbjct: 1296 PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE 1355

Query: 556  PGLPGPPGPPGPPGP------------PAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGA 603
            PGL GPPGPPG PGP            P  +P  P  +G   P    G  G+  P     
Sbjct: 1356 PGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ---GPQGLPGPTGPPG 1412

Query: 604  KKGKNGGPAYE 614
              G+NG P ++
Sbjct: 1413 DPGRNGLPGFD 1423



 Score =  468 bits (1203), Expect = e-131
 Identities = 278/591 (47%), Positives = 319/591 (53%), Gaps = 90/591 (15%)

Query: 111  IPLASLRGEQGPRGEPGPRGPPGPPGLPGH----------GIPGIKGKPG--------PQ 152
            IP   L G  GP+G PG  GPPG PG PG           G PG KG+PG        P 
Sbjct: 703  IPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPP 762

Query: 153  GYPGV----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG-----PQG 197
            G PG           G PG PG PG+ G  G+PG KG++G  G+ GPMG PG      QG
Sbjct: 763  GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822

Query: 198  PPGPHGLPG-IGKPGGPGLPGQ-----------PGPKGDRGPKGLPGPQGLRGPKGDKGF 245
            PPGP G+PG IG+PG  G+PG+           PGP G+RG  G+PG  G  GP G  G 
Sbjct: 823  PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGL 882

Query: 246  ----GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGP 300
                G  G PG KG  GM GPPGP G  G+ G+ GV G  G  G  G+PG PG  G +G 
Sbjct: 883  PGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 301  IGVPGVQGPPG------IPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKP 353
             G PG+ GPPG      +   G+ G+ G+PG PG  G KG QGLPG PG PGL G  G P
Sbjct: 943  KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP 1002

Query: 354  GFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPK 413
            G PGPKG+ G+ G PG +GP G KG IG  G  GP G  G PG  G  G PG+ G PG K
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062

Query: 414  GEGG-----IVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG 468
            G+ G      +G  G PGPKGEPGL G+PG PG  G VG PG+ GLPG  G KG+ G  G
Sbjct: 1063 GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122

Query: 469  VPGLPGVP---GLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPP---GIPGP---KG 519
             PG PG P   G+ GP G PG+PG+ G  G  G PG  GP G  G P   GIPGP   KG
Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG 1182

Query: 520  EPGL-----PGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQ------PGLPGPPGPPGP 567
            EPG      PGPPG PG+ G+ G  GL G PG PG  GP+G+      PG+ GPPGPPG 
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242

Query: 568  PGPPAVMPP-TPPPQGEYLPDMGLGIDGVKPPH------AYGAKKGKNGGP 611
            PGP    P   P PQG        G  G+  P         G  KG+ G P
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNP 1293



 Score =  462 bits (1188), Expect = e-130
 Identities = 285/614 (46%), Positives = 334/614 (54%), Gaps = 77/614 (12%)

Query: 32   GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMK 91
            G+  LP  I P  PP      P+G++         G+A     P +   K  P       
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPVGEK------GIQGVAGNPGQPGIPGPKGDPG------ 656

Query: 92   EIQPAPRMGKEAVP-KKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH----GIPGI- 145
              Q   + GK  +P   G++       G+ G  G+PG  G PG PG+PG     GIPGI 
Sbjct: 657  --QTITQPGKPGLPGNPGRD-------GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707

Query: 146  -KGKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG 203
              G PGP+G+PG+ G PG PG PG+ G  G PG  G  G KGE G   +PGP GPPG  G
Sbjct: 708  LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG-FALPGPPGPPGLPG 766

Query: 204  LPG-IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHG 261
              G +G  G  G PG PGP G  G  GLPGP+G  GP G  G  G PG PG+    G+ G
Sbjct: 767  FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI----GVQG 822

Query: 262  PPGPVGLPG-VGKPGVTGFPGPQGPLGKPG--APGEPGPQGPIGVPGVQGPPGIPGIGKP 318
            PPGP G+PG +G+PG+ G PG +G  G PG   PG PG +G  G+PG  GP G P  G P
Sbjct: 823  PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSP 880

Query: 319  GQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEK 377
            G  G  G  GFPG KGE G+ G PGPPG  GI G+ G PG KGD G+ G PG  GP GEK
Sbjct: 881  GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 378  GPIGAPGIGGPP--------------GEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG 423
            G  G PG+ GPP              GEPGLPGIPG  GP G  G PG  G+ G+ G  G
Sbjct: 941  GSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG 1000

Query: 424  PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKG 483
             PGP G  G  G PG+PG    +GPPG++G  G +G  G  G +G PG  GVP   G  G
Sbjct: 1001 LPGPPGPKGNPGLPGQPGL---IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP---GQPG 1054

Query: 484  EPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHG 542
             PG+PG +G +G PGI         IG PG+PGPKGEPGLPG PG PGI G  G  GL G
Sbjct: 1055 SPGLPGQKGDKGDPGI-------SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 543  PPGKPGALGPQGQPGLPGPPGPPGPPGPPAVM--PPTPPPQGEYLPDMGLGIDGVKPPHA 600
             PG PGA   +GQPGLPG PG PGPPGP  +   P  P   GE  P  G G  G   P  
Sbjct: 1108 LPGTPGA---KGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164

Query: 601  YGAKKGKNG--GPA 612
               K G++G  GPA
Sbjct: 1165 EKGKPGQDGIPGPA 1178



 Score =  460 bits (1183), Expect = e-129
 Identities = 295/660 (44%), Positives = 340/660 (51%), Gaps = 128/660 (19%)

Query: 37   PPQIP------PQMPPQIPQYQPLGQQVPH-MPLAK-DGLAMGKEMPHLQYGKEYPHLPQ 88
            PP +P      P  PP IP   P+GQ   H +P  K D    G ++P     +  P +P 
Sbjct: 812  PPGLPGIGVQGPPGPPGIPG--PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869

Query: 89   YMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKG 147
                I P    G   +P K         +GE G  G PGP   PGP G+PG  G+PG+KG
Sbjct: 870  APGPIGPP---GSPGLPGKAGASGFPGTKGEMGMMGPPGP---PGPLGIPGRSGVPGLKG 923

Query: 148  KPGPQGYPGV-------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPG 200
              G QG PG+       G  G PG+PG PG M  P   G  G+KGE G  GIPG  GP G
Sbjct: 924  DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-PNLLGSKGEKGEPGLPGIPGVSGPKG 982

Query: 201  PHGLPGI----GKPGGPGLPGQPGPKGDRG---------PKGL---------PGPQGLRG 238
              GLPG     G  G PGLPG PGPKG+ G         P GL         PGPQG+ G
Sbjct: 983  YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042

Query: 239  P------------------KGDKG------FGMPGAPGVKGPPGMHGPPGPVGLPG-VGK 273
            P                  KGDKG       G+PG PG KG PG+ G PG  G+ G VG 
Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGD 1102

Query: 274  PGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQ---DGIPGQPGF 329
            PG+ G PG  G  G+PG PG PG  GP G  G+ GPPG PG+ G+PG     G PGQPG 
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGP 1162

Query: 330  PGGKGEQGLPGLPGP------PGLPGIGKPGFPG------PKGDRGMGGVPG---ALGPR 374
            PG KG+ G  G+PGP      PG PG G PG PG       KGD G+ G+PG     GP+
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPK 1222

Query: 375  GEKGPIGAPGIGGPPGEPGLPGI--------PGPMGPPGAIGFPGPKGEGGIVGPQGPPG 426
            GE G  G PG+ GPPG PG PG         PGP GPPG    PGP G  G+ GP+GPPG
Sbjct: 1223 GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR---PGPTGFQGLPGPEGPPG 1279

Query: 427  ---------PKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPG 477
                      KG PG  G PG PG  G+ GPPG++G PG  G  G  G  G+PG+PG PG
Sbjct: 1280 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1339

Query: 478  LLGPKGEPGIPGDQG---LQGPPGIPGIGGPSGP-------IGPPGIPGPKGEPGLPGPP 527
            + GP G PG  G +G   L GPPG PG+ GPSG         GPPGIPG  G  GLPGP 
Sbjct: 1340 MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ 1399

Query: 528  GFPGI----GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGP---PGPPGPPAVMPPTPPP 580
            G  G+    G PG  G +G PG  GA G +G PGLPG PG     GPPGP  +  P  PP
Sbjct: 1400 GPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPP 1459



 Score =  457 bits (1176), Expect = e-128
 Identities = 274/596 (45%), Positives = 310/596 (52%), Gaps = 110/596 (18%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKP---- 149
            P  + G   +P     +     +GE+G  G  GP+G PG PG PG  G PG KG+P    
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 150  ---------GPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQ---KGEIGPMGIPGPQ 196
                     G  G PG  G PG+PG PG+ G  G+PG KGE G    KGE GP G PG  
Sbjct: 552  TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 197  GPP---GPHGLPGIGKP------------GGPGLPGQPGPKGDRGPK-GLPGPQGLRG-P 239
            G P   GP G PG G P            G PG PG PGPKGD G     PG  GL G P
Sbjct: 612  GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 240  KGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV------GKPGVTGFPGPQGPLGKPGAPG 293
              D   G+PG PG+ G PG+ G PG  G PG+      G PG  GFPG  GP G PG PG
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 294  EPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG-IGK 352
              G +GP G PG  GP G PG   PG  G PG PGF G  G +G  G PGPPG PG  G 
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 353  PGFPGPKGDRGMGGVPGAL--------------GPRGEKGPIGAPGIGGPPGE------- 391
             G PGPKGD G  G PG +              GP G  GPIG PG+ G PGE       
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 392  -------------PGLPGIPGPMGPP---------GAIGFPGPKGEGGIVGPQGPPGP-- 427
                         PG+PG PGP+GPP         GA GFPG KGE G++GP GPPGP  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 428  ----------KGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK-----GEAGQKGVPGL 472
                      KG+ GLQG PG PG  GE G  G  GLPGP GP      G  G+KG PGL
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 473  PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG- 531
            PG+PG+ GPKG  G+PGD G  G  G PG+ GP GP G PG+P   G+PGL GPPG  G 
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP---GQPGLIGPPGLKGT 1028

Query: 532  ---IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV-MPPTPPPQGE 583
               +G PG  G+ GPPG  G  G  G PGLPG  G  G PG  ++ +P  P P+GE
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084



 Score =  447 bits (1150), Expect = e-125
 Identities = 304/720 (42%), Positives = 357/720 (49%), Gaps = 161/720 (22%)

Query: 36  LPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQP 95
           +P  I P  PP +    P G   P +P  K  + +  + P  + G++    P       P
Sbjct: 190 IPGPIGPPGPPGL--MGPPGP--PGLPGPKGNMGLNFQGPKGEKGEQGLQGP-------P 238

Query: 96  APRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPP---GPPGLPG--HGIPGIKGKPG 150
            P      + ++ + I +   +G+QG  G+ GP GPP   GPPG PG   G  G +G+PG
Sbjct: 239 GP---PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295

Query: 151 PQGYPGV----GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG 206
            +G PG     G+PG+PG+PG PG  G PG  GE GQKG+ GP G PG   P    G+  
Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT- 354

Query: 207 IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPV 266
           IG+ G  GLPG PG KG+RG  G+ GP GL GP G    G PG PG  G  G  G  GP 
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414

Query: 267 GL-----PGV-GKPGVTGFPGPQGPL----------------GKPGAPGEPGPQGPIGV- 303
           G+     PG+ G+PG  G PGP GP                 G PG+PG+ G QG  GV 
Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474

Query: 304 ------------PGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGE---------QGLPGLP 342
                        G+ GPPG PG+  PG  G PG  GFPG KGE         +GLPG+P
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGL--PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 343 GPPGLPGI----GKPG----FPGPKGDR------------------GMGGVPGALGPRGE 376
           G PG PG     G+PG    FPG KGD+                  G  G+PG  GP+GE
Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE 592

Query: 377 KGPIGAPGIGGPPGEPGLPGIP---GPMGPPGAIGFPGPKGEGGI------VGPQGPPGP 427
            G I   G  GPPG PGLPG+P   GPMGPPG  G PGP GE GI       G  G PGP
Sbjct: 593 PGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 428 KG-------EPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV--PGL 478
           KG       +PG  G PG PG  G+VG PG  GLPG  G  G  G KG PG+PG+  PG 
Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 479 LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG--LPGPPGFPGI---- 532
            GPKG PGIPG     G PG PG  G  GP GPPG PGPKGEPG  LPGPPG PG+    
Sbjct: 712 PGPKGFPGIPGP---PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768

Query: 533 ---------------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP-----GPPGPPA 572
                          G PG  GL G PG  G +GP GQPG  GPPG P     GPPGPP 
Sbjct: 769 GALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 573 VMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
           +  P   P        GL        H    +KG  G P  ++P    E  +P  P GAP
Sbjct: 829 IPGPIGQP--------GL--------HGIPGEKGDPGPPGLDVPGPPGERGSPGIP-GAP 871



 Score =  437 bits (1123), Expect = e-122
 Identities = 292/671 (43%), Positives = 330/671 (49%), Gaps = 151/671 (22%)

Query: 97   PRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG---------HGIPGIKG 147
            PR G      +   I L  L GE+G RG PG +GPPG PG PG          G PG +G
Sbjct: 347  PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406

Query: 148  KPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKG----------EIGQKGEIGPMGIPGPQ- 196
            + G +G PG+  PG PG+ G+PGA G+PG  G          EI + G  GP G PG + 
Sbjct: 407  QKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKG 466

Query: 197  ------------------------GPPGPHGLPGI-GKPGGPGLPGQPGPKGD---RGPK 228
                                    GPPG  GLPG+ G PG  G PGQ G KG     GPK
Sbjct: 467  LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526

Query: 229  GLPGPQG-------------------LRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGL 268
            GLPG  G                     G KGDKG  G PGAPG+ G PG  G  G  GL
Sbjct: 527  GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586

Query: 269  PG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP------GIPGI-GKPGQ 320
            PG  G+PG   F G +GP G PG PG PG  GP+G PG  GPP      GI G+ G PGQ
Sbjct: 587  PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQ 645

Query: 321  DGI-------------PGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367
             GI             PG+PG PG  G  G  GLPG PGLP  G+PG PG  G +G  G+
Sbjct: 646  PGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP--GQPGLPGIPGSKGEPGI 703

Query: 368  PGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGP 427
            PG +G  G  GP G PGI GPPG PG PG  G  GPPG  GFPGPKGE G   P GPPGP
Sbjct: 704  PG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP-GPPGP 761

Query: 428  KGEPGLQGFPGKPGFLGEVGPP------GMRGLPGP---IGPKGEAGQKGVPGLPGV--- 475
             G PG +G  G  G  G  GPP      G+ GLPGP   +GP G+ G  G PGLPG+   
Sbjct: 762  PGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQ 821

Query: 476  -----PGLLGPKGEP---GIPGDQGLQGPPGI-----------PGIGGPSGPIGPP---- 512
                 PG+ GP G+P   GIPG++G  GPPG+           PGI G  GPIGPP    
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 513  --------GIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGP--- 561
                    G PG KGE G+ GPPG P  G  G+ G  G PG  G  G QGQPGLPGP   
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPP--GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 562  ---PGPPGPPGPPAVMPPTPPPQGEYLPDMGL-GIDGVKPPHAYGAKKGKNGGPAYEMPA 617
                G PG PGPP  M P          + GL GI GV  P  Y    G  G      P 
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPG-----QPG 994

Query: 618  FTAELTAPFPP 628
             + +   P PP
Sbjct: 995  LSGQPGLPGPP 1005



 Score =  427 bits (1097), Expect = e-119
 Identities = 263/596 (44%), Positives = 304/596 (51%), Gaps = 125/596 (20%)

Query: 108 GKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-------------HGIP------GIKGK 148
           G +   + ++GE+G RG PG  G PG PG PG              GIP      GI+G 
Sbjct: 35  GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP 94

Query: 149 PGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI 207
           PG  G+PG  G PGMPG  G PG  G+PG  G  G++G  G  G PG QGPPGP G+PG+
Sbjct: 95  PGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154

Query: 208 -GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGP 265
            G+PG   +   PGPKG+ G  G PG QGL GP G  G  G PG PG+ GPPG  G PGP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 266 VGLPGVGKPGVTGFPGPQGPLGKPGAPGE-------------------PGPQGPIGVPGV 306
            G  G+   G  G  G QG  G PG PG+                   PG +GP G PG+
Sbjct: 215 KGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGI 274

Query: 307 QGPPGIPG--IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPKG 360
           +GPPG PG   G+ G+ G PG+ G PG  GE G PG+PG PG PG     G+ G  G KG
Sbjct: 275 RGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKG 334

Query: 361 DRGMGGVPGALGPR-------GEKGPIGAPGIGGPPGEPGLPGIPGP-----------MG 402
           D G  G PG + PR       GEKG IG PG+ G  GE G PGI GP           MG
Sbjct: 335 DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMG 394

Query: 403 PPGAIGFPGPKGEGGIVGP-----QGPPGPKGEPGLQGFPGKPGFLG----------EVG 447
           PPG  GFPG +G+ G  GP      GPPG  G+PG  G PG PG  G          E G
Sbjct: 395 PPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 448 PPGMRGLPGPIGPKGEAGQK----------------GVPGLPGVPGLLGPKGEPGIPGDQ 491
           PPG  G PG  G +GE G K                G PG PG+PGL GP G  G PG +
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 492 ------GLQGPPGIPGI-GGPSGPIGP------------PGIPGPKGEPGLPGPPGFPGI 532
                 G  GP G+PGI G P  P  P            PG+ G KGE G PG PG PG+
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 533 ----GKPGVAGLHGPPGKPGAL------GPQGQPGLPGPPGPPGPPGPPAVMPPTP 578
               G+ G+ GL GP G+PG +      GP G PGLPG PG  GP GPP   PP P
Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGP 630



 Score =  422 bits (1085), Expect = e-118
 Identities = 263/589 (44%), Positives = 299/589 (50%), Gaps = 99/589 (16%)

Query: 116 LRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMG 173
           L G  GP G PGPRG  G  G+PG  G  GI+G PG  G+PG  G PGMPG  G PG  G
Sbjct: 61  LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG 120

Query: 174 MPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGPKGLPG 232
           +PG  G  G++G  G  G PG QGPPGP G+PG+ G+PG   +   PGPKG+ G  G PG
Sbjct: 121 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 233 PQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGA 291
            QGL GP G  G  G PG PG+ GPPG  G PGP G  G+   G  G  G QG  G PG 
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 292 PGE-------------------PGPQGPIGVPGVQGPPGIPG--IGKPGQDGIPGQPGFP 330
           PG+                   PG +GP G PG++GPPG PG   G+ G+ G PG+ G P
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 331 GGKGEQGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPR-------GEKGP 379
           G  GE G PG+PG PG PG     G+ G  G KGD G  G PG + PR       GEKG 
Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 380 IGAPGIGGPPGEPGLPGIPGP-----------MGPPGAIGFPGPKGEGGIVGPQG----- 423
           IG PG+ G  GE G PGI GP           MGPPG  GFPG +G+ G  GP G     
Sbjct: 361 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG 420

Query: 424 PPGPKGEPGLQGFPGKPGFLG----------EVGPPGMRGLPGPIGPKGEAGQKG----- 468
           PPG  G+PG  G PG PG  G          E GPPG  G PG  G +GE G KG     
Sbjct: 421 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 480

Query: 469 -----------VPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGP 517
                       PG PG+PGL GP G  G PG +G +G        G +GP G PGIPG 
Sbjct: 481 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ------AGATGPKGLPGIPGA 534

Query: 518 KGEPGLPGPPG-------FPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPG 569
            G PG PG  G       FPG+ G  G  G  G PG PG  G  GQ GLPG PGP G PG
Sbjct: 535 PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG 594

Query: 570 PPAVMPPTPPPQGEYLPDM-----GLGIDGVKPPHAYGAK--KGKNGGP 611
                    PP    LP +      +G  G  PP   G K  +G  G P
Sbjct: 595 GITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNP 643



 Score =  421 bits (1081), Expect = e-117
 Identities = 268/612 (43%), Positives = 303/612 (49%), Gaps = 141/612 (23%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGH-------GIPGIKGKPGPQGYPGV----------GK 159
           +G+ G  G PGP+G  GPPGLPG        G+PG  G PGPQG PG           G 
Sbjct: 77  KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136

Query: 160 PGMPGMPGKPGAMGMPGAKGEIGQ---------KGEIGPMGIPGPQGPPGPHGLPG-IGK 209
           PG PG+ G PG  G+PG KGE G          KG  G  G PG QG PGP G+PG IG 
Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 210 PGGPGL------PGQPGPKGD-----RGPKGLPGPQGLRGPKGDKGF------------- 245
           PG PGL      PG PGPKG+     +GPKG  G QGL+GP G  G              
Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256

Query: 246 ----GMPGAPGVKGPPGMHGPPGPVG----------LPGV----GKPGVTGFPGPQGPLG 287
               G+PG  G  GPPG+ GPPGP G           PG     GK G  G PG  G  G
Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 288 KPGAPGEPGPQGPIGVPGVQGPPGIPGIGKP--------GQDGIPGQPGFPGGKGEQGLP 339
            PG PGEPG  G  G  G  GPPG PG+  P        G+ G  G PG PG KGE+G P
Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 340 GLPGPPGLPGI---------GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG 390
           G+ GPPGLPG          G PGFPG +G +G  G PG   P       G PG+ G PG
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP-------GPPGLDGQPG 429

Query: 391 EPGLPGIPGPMGP----------PGAIGFPGPKGEGGIVGPQGPPGPKGEP-------GL 433
            PGLPG PGP GP          PG  G PG  G+ G+ G QG  G KG+        G+
Sbjct: 430 APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 434 QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG------VPGLPGVPGLLGPKGEPGI 487
            G PG+PG  G  GPPG  G PG  G KG+AG  G      +PG PG PG  G KGEPG 
Sbjct: 490 SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549

Query: 488 ----------PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG------LPGPPGFPG 531
                      G+ G  G PG+PG+ G  G  G PG+PGPKGEPG        GPPG PG
Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 532 I-GKPGVAGLHGPPG--KPGALGPQG------QPGLPGPPGPPGPPGPPAVMPPTPPPQG 582
           + G PG  G  GPPG   PG +G +G       PG PG PGP G PG     P  P   G
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 583 EYLPDMGLGIDG 594
               D  +G+ G
Sbjct: 670 NPGRDGDVGLPG 681



 Score =  393 bits (1009), Expect = e-109
 Identities = 220/445 (49%), Positives = 249/445 (55%), Gaps = 64/445 (14%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPG------------------HGIPGIKGKPGPQGYPG--- 156
            G QG  G PGP G PG PG PG                   G+PG KG+PG  GYPG   
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 157  ----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPG 211
                VG PG+PG+PG PGA G PG  G  G  G  GP GI GP G PG  G PG +G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 212  GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGV------KGPPGMHGPPGP 265
             PG PG PG KG  G  G+PGP G +G  G  GFG PG PG+      KG  G+ G PG 
Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGN 1215

Query: 266  VGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----GKPGQ 320
             GLPG  G+PG  GFPG QGP G PG+PG P  +GP G PG QGPPG PG     G PG 
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGPTGFQGLPGP 1274

Query: 321  DGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----------GKPGFPGPKGDRGMGGVPGA 370
            +G PG PG  G KGE+G PG PG PGLPG+          G PG PG  G +G  G+PG 
Sbjct: 1275 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1334

Query: 371  LGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV-GPQGPPGPKG 429
             G  G KGP G PG  GP GEPGL      +GPPG  G PGP G+  I+ G  GPPG  G
Sbjct: 1335 PGFPGMKGPSGVPGSAGPEGEPGL------IGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1388

Query: 430  EPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPG 489
            +PGL+G PG         P G +GLPGP GP G+ G+ G+PG  G  G  G  G PG PG
Sbjct: 1389 QPGLKGLPG---------PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG 1439

Query: 490  DQGLQGPPGIPGIGGPSGPIGPPGI 514
             +GL GPPG  G+ GP GP G   +
Sbjct: 1440 TRGLDGPPGPDGLQGPPGPPGTSSV 1464



 Score =  388 bits (997), Expect = e-108
 Identities = 246/562 (43%), Positives = 282/562 (50%), Gaps = 133/562 (23%)

Query: 144 GIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG 203
           GIKG+ G +G+PG+   G PG+PG PG  G PG +G+ G  G      IPGP GP G  G
Sbjct: 42  GIKGEKGERGFPGL--EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIRG 93

Query: 204 LPGI-GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHG 261
            PG+ G PG PGLPG PG  G  GP+G+P   G  G KG++GF G PG PG++GPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIP---GCNGTKGERGFPGSPGFPGLQGPPGPPG 150

Query: 262 PPGPVGLPG-------VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG 314
            PG  G PG        G  G  G+PGP G  G PG  G PGP GP G PG+ GPPG PG
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 315 I---------------GKPGQDGIPGQPGFPG-------------GKGEQGLPGLPGPPG 346
           +               G+ G+ G+ G PG PG              KG+QGLPG  GPPG
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270

Query: 347 LPGI-GKPGFP-GPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP------ 398
            PGI G PG P G KG++G  G PG  G  G+ G  G PGI G PG+PG PG P      
Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330

Query: 399 ------GPMGPPGAI-------------------GFPGPKGEGGIVGPQGPPGPKGEPG- 432
                 GP GPPG +                   G PG KGE G  G QGPPG  G PG 
Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390

Query: 433 -LQGFPGKPGFLGEVGPPGMRGLPGPI--GPKGEAGQKGVPGLPGVPGLL---------- 479
            + G PG PGF GE G  G  G PG    GP G  GQ G PGLPG PG            
Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEI 450

Query: 480 ---GPKGEPGIPGDQGLQ-------------------------GPPGIPGIGGPSGPIGP 511
              GP G PG PGD+GLQ                         G PG+PG+ GP G +G 
Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 512 PGIPGPKGEPGLPGPPGFPGI----GKPGVAGLHGPPGK----PGALGPQGQPGLPGPPG 563
           PG  G KG+ G  GP G PGI    G PG  G  G PG     PG  G +G+ G PG PG
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG 570

Query: 564 PPGPPGPPAV--MPPTPPPQGE 583
            PG PG P    +P  P P+GE
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGE 592



 Score =  308 bits (788), Expect = 2e-83
 Identities = 207/462 (44%), Positives = 238/462 (51%), Gaps = 50/462 (10%)

Query: 235 GLRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPG 293
           G++G KG++GF G+ G PG+ G PG  GPPGP G  G    G+ G PGP+G  G PG PG
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKG--DDGIPGPPGPKGIRGPPGLPG 99

Query: 294 EPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GK 352
            PG  G  G+PG  G PG  GI  PG +G  G+ GFPG  G  GL G PGPPG+PG+ G+
Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGI--PGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 353 PG------FPGPKGDRGMGGVPGALG---PRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP 403
           PG       PGPKG+ G  G PG  G   P G  GPIG PG  G  G PG PG+PGP G 
Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 404 PGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP----------GKPGFLGEVGPPGMRG 453
            G + F GPKGE G  G QGPPGP G+   Q  P          G PG  G  GPPG+RG
Sbjct: 218 MG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276

Query: 454 LPGPIG-PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPP 512
            PGP G  KGE G++G PG  G PG  G  G+PGIPG   L G PG PG  G  G  G  
Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPG---LPGDPGYPGEPGRDGEKGQK 333

Query: 513 GIPGPKGEPGL--PGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP----- 565
           G  GP G PGL  P P     IG+ G  GL G PG+ G  G  G  G PG PGPP     
Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 566 GPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAF-----TA 620
           GPPGPP   P     +G+  P  G+ I G   P     + G  G P    PA      + 
Sbjct: 394 GPPGPPG-FPGERGQKGDEGPP-GISIPG---PPGLDGQPGAPGLPGPPGPAGPHIPPSD 448

Query: 621 ELTAPFPPVGAPVKFNKLLYNGRQNYNPQTG--IFTCEVPGV 660
           E+  P PP G P         G Q      G   F C   G+
Sbjct: 449 EICEPGPP-GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489



 Score =  271 bits (693), Expect = 2e-72
 Identities = 167/380 (43%), Positives = 197/380 (51%), Gaps = 50/380 (13%)

Query: 285 PLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----------GKPGQDGIPGQPGFPGGKG 334
           P  K    G  G +G  G PG++G PG+PG           G+ G DGIPG PG  G +G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 335 EQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG 393
             GLPG PG PGLPG+ G  G PGP+      G+PG  G +GE+G  G+PG  G  G PG
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQ------GIPGCNGTKGERGFPGSPGFPGLQGPPG 147

Query: 394 LPGIPGPMGPPGAI---GFPGPKGEGGIVGP---QGPPGPKGEPGLQGFPGKPGFLGEVG 447
            PGIPG  G PG+I     PGPKG  G  GP   QG PGP G PG  G PG PG +G  G
Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPG 207

Query: 448 PPGMRGLPGPI-----GPKGEAGQKGVPGLPGVPGLLG----------PKGEPGIPGDQG 492
           PPG+ G  G +     GPKGE G++G+ G PG PG +            KG+ G+PGD  
Sbjct: 208 PPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD-- 265

Query: 493 LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG----IGKPGVAGLHGPPGKPG 548
            +GPPG PGI GP GP  P G  G KGE G PG  G PG     G+PG+ GL G PG PG
Sbjct: 266 -RGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322

Query: 549 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN 608
             G  G+ G  G  GPPGPPG     P T    GE      +G+ G+          G  
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE---KGNIGLPGLPGEKGERGFPGIQ 379

Query: 609 GGPAYEMPAFTAELTAPFPP 628
           G P    P   A +  P PP
Sbjct: 380 GPPGLPGPPGAAVMGPPGPP 399


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  475 bits (1222), Expect = e-134
 Identities = 294/663 (44%), Positives = 338/663 (50%), Gaps = 136/663 (20%)

Query: 84   PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASL---RGEQGPRGEPGP-----------R 129
            P LP +   + P    G    P       L  L   +G+ GP G+PGP           +
Sbjct: 762  PGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQ 821

Query: 130  GPPGPPGLPG-------HGIPGIKGKPGP-----------QGYPGV-------GKPGMPG 164
            GPPGPPG+PG       HGIPG KG PGP           +G PG+       G PG PG
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 165  MPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKPGGPGLPGQPG 220
            +PGK GA G PG KGE+G    +GP G PGP G PG  G+PG+    G  G PGLPG  G
Sbjct: 882  LPGKAGASGFPGTKGEMGM---MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTG 938

Query: 221  PKGDRGPKGLPGPQG-----LRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPGVGKP 274
             KG +G  GLPGP G     L G KG+KG  G+PG PGV GP G  G PG  G PG+   
Sbjct: 939  EKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLS-- 996

Query: 275  GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----GKPGQDGIPGQPGFP 330
            G  G PGP GP G PG PG+PG  GP G+ G  G  G PG     G PG  G+PGQPG P
Sbjct: 997  GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056

Query: 331  GGKGEQG-----------LPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKG 378
            G  G++G           LPGLPGP G PG+ G PG PG KG  G  G+PG  G  G KG
Sbjct: 1057 GLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116

Query: 379  PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPG 438
              G PG  G PG PG  GI GP G PG  G PGP G GG  G  GPPG KG+PG  G PG
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG 1176

Query: 439  KPGFLGEVGPPGMRGLPGPIGPKGEAGQKG---VPGLPGVPGLLGPKGEPGIPGDQGLQG 495
              G  GE G PG  G PGP G  G +GQKG   +PG+PG PGL GPKGEPG  G  G+QG
Sbjct: 1177 PAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG 1235

Query: 496  PPGIPGIGGPS-----------GPIGPPGIPGPKGEPGLPG------------PPGFPGI 532
            PPG PG  GP+           GP G PG+PGP+G PGLPG             PG PG+
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1295

Query: 533  -------------------------------GKPGVAGLHGPPGKPGALGPQGQPGLPGP 561
                                           G PG  G+ GP G PG+ GP+G+PGL GP
Sbjct: 1296 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1355

Query: 562  PGP---PGPPGPPAVMPPTPPPQGEYLPDM-GL-GIDGVKPPHAYGAKKGKNGGPAYE-M 615
            PGP   PGP G   ++     P G  +P   GL G+ G + P       G  G P    +
Sbjct: 1356 PGPPGLPGPSGQSIIIKGDAGPPG--IPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL 1413

Query: 616  PAF 618
            P F
Sbjct: 1414 PGF 1416



 Score =  469 bits (1206), Expect = e-132
 Identities = 279/588 (47%), Positives = 321/588 (54%), Gaps = 90/588 (15%)

Query: 111  IPLASLRGEQGPRGEPGPRGPPGPPGLPGH----------GIPGIKGKPG--------PQ 152
            IP   L G  GP+G PG  GPPG PG PG           G PG KG+PG        P 
Sbjct: 703  IPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPP 762

Query: 153  GYPGV----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG-----PQG 197
            G PG           G PG PG PG+ G  G+PG KG++G  G+ GPMG PG      QG
Sbjct: 763  GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822

Query: 198  PPGPHGLPG-IGKPGGPGLPGQ-----------PGPKGDRGPKGLPGPQGLRGPKGDKGF 245
            PPGP G+PG IG+PG  G+PG+           PGP G+RG  G+PG  G  GP G  G 
Sbjct: 823  PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGL 882

Query: 246  ----GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGP 300
                G  G PG KG  GM GPPGP G  G+ G+ GV G  G  G  G+PG PG  G +G 
Sbjct: 883  PGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 301  IGVPGVQGPPG------IPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKP 353
             G PG+ GPPG      +   G+ G+ G+PG PG  G KG QGLPG PG PGL G  G P
Sbjct: 943  KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP 1002

Query: 354  GFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPK 413
            G PGPKG+ G+ G PG +GP G KG IG  G  GP G  G PG  G  G PG+ G PG K
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062

Query: 414  GEGG-----IVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG 468
            G+ G      +G  G PGPKGEPGL G+PG PG  G VG PG+ GLPG  G KG+ G  G
Sbjct: 1063 GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122

Query: 469  VPGLPGVP---GLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPP---GIPGP---KG 519
             PG PG P   G+ GP G PG+PG+ G  G  G PG  GP G  G P   GIPGP   KG
Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG 1182

Query: 520  EPGL-----PGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQ------PGLPGPPGPPGP 567
            EPG      PGPPG PG+ G+ G  GL G PG PG  GP+G+      PG+ GPPGPPG 
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242

Query: 568  PGPPAVMPP-TPPPQGEYLPDMGLGIDGVKPPHAY---GAKKGKNGGP 611
            PGP    P   P PQG   P    G+ G + P      G  KG+ G P
Sbjct: 1243 PGPALEGPKGNPGPQG---PPGRPGLPGPEGPPGLPGNGGIKGEKGNP 1287



 Score =  465 bits (1196), Expect = e-131
 Identities = 284/607 (46%), Positives = 325/607 (53%), Gaps = 83/607 (13%)

Query: 37   PPQIP------PQMPPQIPQYQPLGQQVPH-MPLAK-DGLAMGKEMPHLQYGKEYPHLPQ 88
            PP +P      P  PP IP   P+GQ   H +P  K D    G ++P     +  P +P 
Sbjct: 812  PPGLPGIGVQGPPGPPGIPG--PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869

Query: 89   YMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKG 147
                I P    G   +P K         +GE G  G PGP   PGP G+PG  G+PG+KG
Sbjct: 870  APGPIGPP---GSPGLPGKAGASGFPGTKGEMGMMGPPGP---PGPLGIPGRSGVPGLKG 923

Query: 148  KPGPQGYPGV-------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPG 200
              G QG PG+       G  G PG+PG PG M  P   G  G+KGE G  GIPG  GP G
Sbjct: 924  DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-PNLLGSKGEKGEPGLPGIPGVSGPKG 982

Query: 201  PHGLPGI-GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG----FGMPGAPGVKG 255
              GLPG  G+PG  G PG PGP G +G  GLPG  GL GP G KG     G PG  GV+G
Sbjct: 983  YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042

Query: 256  PPGMHGPPGPVGLPGV-------GKPGVT-----GFPGPQGPLGKPGAPGEPGPQGPIGV 303
            PPG  G PG  G PG+       G PG++     G PGP+G  G PG PG PG +G +G 
Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGD 1102

Query: 304  PGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGP 358
            PG+ G PG PG  G+PG  G PG PG PG KG  G PG PG PG PG     G PG PGP
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGP 1162

Query: 359  KGDRGMGGVPGALGPRGEKGPIGAPGIG--GPPGEPGL---------------PGIPGPM 401
             G++G  G  G  GP G+KG  G PG G  GPPG PGL               PG+PGP 
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPK 1222

Query: 402  GPPGAIGFPGPKGEGGIVGPQGPP--GPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIG 459
            G PG  GFPG +G  G  G  GP   GPKG PG QG PG+PG  G  GPPG+ G  G  G
Sbjct: 1223 GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKG 1282

Query: 460  PKGEAGQKGVPGLPGV------PGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513
             KG  GQ G+PGLPG+      PGL G  G PG+ G +G  G PG+PG  G  GP G PG
Sbjct: 1283 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG 1342

Query: 514  IPGPKGEPGLPGPPGFPGI-----------GKPGVAGLHGPPGKPGALGPQGQPGLPGPP 562
              GP+GEPGL GPPG PG+           G  G  G+ G PG  G  GPQG  GLPGP 
Sbjct: 1343 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1402

Query: 563  GPPGPPG 569
            GPPG PG
Sbjct: 1403 GPPGDPG 1409



 Score =  463 bits (1192), Expect = e-130
 Identities = 301/698 (43%), Positives = 355/698 (50%), Gaps = 128/698 (18%)

Query: 32   GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMK 91
            G+  LP  I P  PP      P+G++         G+A     P +   K  P       
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPVGEK------GIQGVAGNPGQPGIPGPKGDPG------ 656

Query: 92   EIQPAPRMGKEAVP-KKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH----GIPGI- 145
              Q   + GK  +P   G++       G+ G  G+PG  G PG PG+PG     GIPGI 
Sbjct: 657  --QTITQPGKPGLPGNPGRD-------GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707

Query: 146  -KGKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG 203
              G PGP+G+PG+ G PG PG PG+ G  G PG  G  G KGE G   +PGP GPPG  G
Sbjct: 708  LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG-FALPGPPGPPGLPG 766

Query: 204  LPG-IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHG 261
              G +G  G  G PG PGP G  G  GLPGP+G  GP G  G  G PG PG+    G+ G
Sbjct: 767  FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI----GVQG 822

Query: 262  PPGPVGLPG-VGKPGVTGFPGPQGPLGKPG--APGEPGPQGPIGVPGVQGPPGIPGIGKP 318
            PPGP G+PG +G+PG+ G PG +G  G PG   PG PG +G  G+PG  GP G P  G P
Sbjct: 823  PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSP 880

Query: 319  GQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEK 377
            G  G  G  GFPG KGE G+ G PGPPG  GI G+ G PG KGD G+ G PG  GP GEK
Sbjct: 881  GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 378  GPIGAPGIGGPP--------------GEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGP-- 421
            G  G PG+ GPP              GEPGLPGIPG  GP G  G PG  G+ G+ G   
Sbjct: 941  GSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG 1000

Query: 422  -QGPPGPKGEPGLQGF------PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP- 473
              GPPGPKG PGL G       PG  G +G++G PG +G+ GP GP G  GQ G PGLP 
Sbjct: 1001 LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 474  -------------GVPGLLGPKGEPGIP------------GDQGLQGPPGIPGIGGPSGP 508
                         G+PGL GPKGEPG+P            GD GL G PG PG  G  G 
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120

Query: 509  IGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGP--- 564
             G PG PGP G  G+ GPPG PG+ G+PG  G  G PG+PG  G +G+PG  G PGP   
Sbjct: 1121 PGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQ 1180

Query: 565  -----------PGPPGPPAVM--------------PPTPPPQGEYLPDMGLGIDGVK--- 596
                       PGPPG P +               P  P P+GE  P    G  GV+   
Sbjct: 1181 KGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE--PGFH-GFPGVQGPP 1237

Query: 597  -PPHAYG-AKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
             PP + G A +G  G P  + P     L  P  P G P
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLP 1275



 Score =  457 bits (1176), Expect = e-128
 Identities = 274/596 (45%), Positives = 310/596 (52%), Gaps = 110/596 (18%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKP---- 149
            P  + G   +P     +     +GE+G  G  GP+G PG PG PG  G PG KG+P    
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 150  ---------GPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQ---KGEIGPMGIPGPQ 196
                     G  G PG  G PG+PG PG+ G  G+PG KGE G    KGE GP G PG  
Sbjct: 552  TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 197  GPP---GPHGLPGIGKP------------GGPGLPGQPGPKGDRGPK-GLPGPQGLRG-P 239
            G P   GP G PG G P            G PG PG PGPKGD G     PG  GL G P
Sbjct: 612  GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 240  KGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV------GKPGVTGFPGPQGPLGKPGAPG 293
              D   G+PG PG+ G PG+ G PG  G PG+      G PG  GFPG  GP G PG PG
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 294  EPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG-IGK 352
              G +GP G PG  GP G PG   PG  G PG PGF G  G +G  G PGPPG PG  G 
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 353  PGFPGPKGDRGMGGVPGAL--------------GPRGEKGPIGAPGIGGPPGE------- 391
             G PGPKGD G  G PG +              GP G  GPIG PG+ G PGE       
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 392  -------------PGLPGIPGPMGPP---------GAIGFPGPKGEGGIVGPQGPPGP-- 427
                         PG+PG PGP+GPP         GA GFPG KGE G++GP GPPGP  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 428  ----------KGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK-----GEAGQKGVPGL 472
                      KG+ GLQG PG PG  GE G  G  GLPGP GP      G  G+KG PGL
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 473  PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG- 531
            PG+PG+ GPKG  G+PGD G  G  G PG+ GP GP G PG+P   G+PGL GPPG  G 
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP---GQPGLIGPPGLKGT 1028

Query: 532  ---IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV-MPPTPPPQGE 583
               +G PG  G+ GPPG  G  G  G PGLPG  G  G PG  ++ +P  P P+GE
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084



 Score =  452 bits (1163), Expect = e-127
 Identities = 280/601 (46%), Positives = 321/601 (53%), Gaps = 109/601 (18%)

Query: 116  LRGEQGPRGEPG------PRGPPGPPGLPGHGIPGIKGKPGPQGY--PG-VGKPGMPGMP 166
            L G  GP+GEPG       RGPPG PGLPG  +PG  G  GP G+  PG VG+ G+ G+ 
Sbjct: 583  LPGLPGPKGEPGGITFKGERGPPGNPGLPG--LPGNIGPMGPPGFGPPGPVGEKGIQGVA 640

Query: 167  GKPGAMGMPGAKGEIGQK-------------GEIGPMGIPGPQGPPGPHGLPGI-GKPGG 212
            G PG  G+PG KG+ GQ              G  G +G+PG  G PG  GLPGI G  G 
Sbjct: 641  GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 213  PGLPG--QPGPKGDRGPKGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPG--MHGPPG 264
            PG+PG   PGP G +G  G+PGP G  G  G  G     G PG PG KG PG  + GPPG
Sbjct: 701  PGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG 760

Query: 265  PVGLPG----VGKPGVTGFPGPQGPLGKPGAPGEPGPQ---GPIGVPGVQGPPGIPGIGK 317
            P GLPG    +G  G  GFPGP GP G+ G  G PGP+   GP G PG  GPPG+PGIG 
Sbjct: 761  PPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGV 820

Query: 318  PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGE- 376
             G  G PG PG  G  G  G+PG  G PG PG+  PG PG +G  G+ G PG +GP G  
Sbjct: 821  QGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSP 880

Query: 377  --KGPIGAPGIGGPPGEPGL---PGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEP 431
               G  GA G  G  GE G+   PG PGP+G PG  G PG KG+ G+ G  G PGP GE 
Sbjct: 881  GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 432  GLQGFPGKP-----------GFLGEVGPPGMRGLPGPIGPK------GEAGQKGVPGLPG 474
            G +G PG P           G  GE G PG+ G+PG  GPK      G+ GQ G+ G PG
Sbjct: 941  GSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG 1000

Query: 475  VPGLLGPKGEPGIPGDQGLQGPPGI------------PGIGGPSGP-------------- 508
            +PG  GPKG PG+PG  GL GPPG+             G+ GP GP              
Sbjct: 1001 LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 509  ------------IGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQ 555
                        IG PG+PGPKGEPGLPG PG PGI G  G  GL G PG PGA   +GQ
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA---KGQ 1117

Query: 556  PGLPGPPGPPGPPGPPAVM--PPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNG--GP 611
            PGLPG PG PGPPGP  +   P  P   GE  P  G G  G   P     K G++G  GP
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177

Query: 612  A 612
            A
Sbjct: 1178 A 1178



 Score =  447 bits (1150), Expect = e-125
 Identities = 304/720 (42%), Positives = 357/720 (49%), Gaps = 161/720 (22%)

Query: 36  LPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQP 95
           +P  I P  PP +    P G   P +P  K  + +  + P  + G++    P       P
Sbjct: 190 IPGPIGPPGPPGL--MGPPGP--PGLPGPKGNMGLNFQGPKGEKGEQGLQGP-------P 238

Query: 96  APRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPP---GPPGLPG--HGIPGIKGKPG 150
            P      + ++ + I +   +G+QG  G+ GP GPP   GPPG PG   G  G +G+PG
Sbjct: 239 GP---PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295

Query: 151 PQGYPGV----GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG 206
            +G PG     G+PG+PG+PG PG  G PG  GE GQKG+ GP G PG   P    G+  
Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT- 354

Query: 207 IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPV 266
           IG+ G  GLPG PG KG+RG  G+ GP GL GP G    G PG PG  G  G  G  GP 
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414

Query: 267 GL-----PGV-GKPGVTGFPGPQGPL----------------GKPGAPGEPGPQGPIGV- 303
           G+     PG+ G+PG  G PGP GP                 G PG+PG+ G QG  GV 
Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474

Query: 304 ------------PGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGE---------QGLPGLP 342
                        G+ GPPG PG+  PG  G PG  GFPG KGE         +GLPG+P
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGL--PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 343 GPPGLPGI----GKPG----FPGPKGDR------------------GMGGVPGALGPRGE 376
           G PG PG     G+PG    FPG KGD+                  G  G+PG  GP+GE
Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE 592

Query: 377 KGPIGAPGIGGPPGEPGLPGIP---GPMGPPGAIGFPGPKGEGGI------VGPQGPPGP 427
            G I   G  GPPG PGLPG+P   GPMGPPG  G PGP GE GI       G  G PGP
Sbjct: 593 PGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 428 KG-------EPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV--PGL 478
           KG       +PG  G PG PG  G+VG PG  GLPG  G  G  G KG PG+PG+  PG 
Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 479 LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG--LPGPPGFPGI---- 532
            GPKG PGIPG     G PG PG  G  GP GPPG PGPKGEPG  LPGPPG PG+    
Sbjct: 712 PGPKGFPGIPGP---PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768

Query: 533 ---------------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP-----GPPGPPA 572
                          G PG  GL G PG  G +GP GQPG  GPPG P     GPPGPP 
Sbjct: 769 GALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 573 VMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
           +  P   P        GL        H    +KG  G P  ++P    E  +P  P GAP
Sbjct: 829 IPGPIGQP--------GL--------HGIPGEKGDPGPPGLDVPGPPGERGSPGIP-GAP 871



 Score =  437 bits (1123), Expect = e-122
 Identities = 292/671 (43%), Positives = 330/671 (49%), Gaps = 151/671 (22%)

Query: 97   PRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG---------HGIPGIKG 147
            PR G      +   I L  L GE+G RG PG +GPPG PG PG          G PG +G
Sbjct: 347  PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406

Query: 148  KPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKG----------EIGQKGEIGPMGIPGPQ- 196
            + G +G PG+  PG PG+ G+PGA G+PG  G          EI + G  GP G PG + 
Sbjct: 407  QKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKG 466

Query: 197  ------------------------GPPGPHGLPGI-GKPGGPGLPGQPGPKGD---RGPK 228
                                    GPPG  GLPG+ G PG  G PGQ G KG     GPK
Sbjct: 467  LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526

Query: 229  GLPGPQG-------------------LRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGL 268
            GLPG  G                     G KGDKG  G PGAPG+ G PG  G  G  GL
Sbjct: 527  GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586

Query: 269  PG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP------GIPGI-GKPGQ 320
            PG  G+PG   F G +GP G PG PG PG  GP+G PG  GPP      GI G+ G PGQ
Sbjct: 587  PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQ 645

Query: 321  DGI-------------PGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367
             GI             PG+PG PG  G  G  GLPG PGLP  G+PG PG  G +G  G+
Sbjct: 646  PGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP--GQPGLPGIPGSKGEPGI 703

Query: 368  PGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGP 427
            PG +G  G  GP G PGI GPPG PG PG  G  GPPG  GFPGPKGE G   P GPPGP
Sbjct: 704  PG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP-GPPGP 761

Query: 428  KGEPGLQGFPGKPGFLGEVGPP------GMRGLPGP---IGPKGEAGQKGVPGLPGV--- 475
             G PG +G  G  G  G  GPP      G+ GLPGP   +GP G+ G  G PGLPG+   
Sbjct: 762  PGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQ 821

Query: 476  -----PGLLGPKGEP---GIPGDQGLQGPPGI-----------PGIGGPSGPIGPP---- 512
                 PG+ GP G+P   GIPG++G  GPPG+           PGI G  GPIGPP    
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 513  --------GIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGP--- 561
                    G PG KGE G+ GPPG P  G  G+ G  G PG  G  G QGQPGLPGP   
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPP--GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 562  ---PGPPGPPGPPAVMPPTPPPQGEYLPDMGL-GIDGVKPPHAYGAKKGKNGGPAYEMPA 617
                G PG PGPP  M P          + GL GI GV  P  Y    G  G      P 
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPG-----QPG 994

Query: 618  FTAELTAPFPP 628
             + +   P PP
Sbjct: 995  LSGQPGLPGPP 1005



 Score =  427 bits (1097), Expect = e-119
 Identities = 263/596 (44%), Positives = 304/596 (51%), Gaps = 125/596 (20%)

Query: 108 GKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-------------HGIP------GIKGK 148
           G +   + ++GE+G RG PG  G PG PG PG              GIP      GI+G 
Sbjct: 35  GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP 94

Query: 149 PGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI 207
           PG  G+PG  G PGMPG  G PG  G+PG  G  G++G  G  G PG QGPPGP G+PG+
Sbjct: 95  PGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154

Query: 208 -GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGP 265
            G+PG   +   PGPKG+ G  G PG QGL GP G  G  G PG PG+ GPPG  G PGP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 266 VGLPGVGKPGVTGFPGPQGPLGKPGAPGE-------------------PGPQGPIGVPGV 306
            G  G+   G  G  G QG  G PG PG+                   PG +GP G PG+
Sbjct: 215 KGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGI 274

Query: 307 QGPPGIPG--IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPKG 360
           +GPPG PG   G+ G+ G PG+ G PG  GE G PG+PG PG PG     G+ G  G KG
Sbjct: 275 RGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKG 334

Query: 361 DRGMGGVPGALGPR-------GEKGPIGAPGIGGPPGEPGLPGIPGP-----------MG 402
           D G  G PG + PR       GEKG IG PG+ G  GE G PGI GP           MG
Sbjct: 335 DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMG 394

Query: 403 PPGAIGFPGPKGEGGIVGP-----QGPPGPKGEPGLQGFPGKPGFLG----------EVG 447
           PPG  GFPG +G+ G  GP      GPPG  G+PG  G PG PG  G          E G
Sbjct: 395 PPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 448 PPGMRGLPGPIGPKGEAGQK----------------GVPGLPGVPGLLGPKGEPGIPGDQ 491
           PPG  G PG  G +GE G K                G PG PG+PGL GP G  G PG +
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 492 ------GLQGPPGIPGI-GGPSGPIGP------------PGIPGPKGEPGLPGPPGFPGI 532
                 G  GP G+PGI G P  P  P            PG+ G KGE G PG PG PG+
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 533 ----GKPGVAGLHGPPGKPGAL------GPQGQPGLPGPPGPPGPPGPPAVMPPTP 578
               G+ G+ GL GP G+PG +      GP G PGLPG PG  GP GPP   PP P
Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGP 630



 Score =  422 bits (1085), Expect = e-118
 Identities = 263/589 (44%), Positives = 299/589 (50%), Gaps = 99/589 (16%)

Query: 116 LRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMG 173
           L G  GP G PGPRG  G  G+PG  G  GI+G PG  G+PG  G PGMPG  G PG  G
Sbjct: 61  LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG 120

Query: 174 MPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGPKGLPG 232
           +PG  G  G++G  G  G PG QGPPGP G+PG+ G+PG   +   PGPKG+ G  G PG
Sbjct: 121 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 233 PQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGA 291
            QGL GP G  G  G PG PG+ GPPG  G PGP G  G+   G  G  G QG  G PG 
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 292 PGE-------------------PGPQGPIGVPGVQGPPGIPG--IGKPGQDGIPGQPGFP 330
           PG+                   PG +GP G PG++GPPG PG   G+ G+ G PG+ G P
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 331 GGKGEQGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPR-------GEKGP 379
           G  GE G PG+PG PG PG     G+ G  G KGD G  G PG + PR       GEKG 
Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 380 IGAPGIGGPPGEPGLPGIPGP-----------MGPPGAIGFPGPKGEGGIVGPQG----- 423
           IG PG+ G  GE G PGI GP           MGPPG  GFPG +G+ G  GP G     
Sbjct: 361 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG 420

Query: 424 PPGPKGEPGLQGFPGKPGFLG----------EVGPPGMRGLPGPIGPKGEAGQKG----- 468
           PPG  G+PG  G PG PG  G          E GPPG  G PG  G +GE G KG     
Sbjct: 421 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 480

Query: 469 -----------VPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGP 517
                       PG PG+PGL GP G  G PG +G +G        G +GP G PGIPG 
Sbjct: 481 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ------AGATGPKGLPGIPGA 534

Query: 518 KGEPGLPGPPG-------FPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPG 569
            G PG PG  G       FPG+ G  G  G  G PG PG  G  GQ GLPG PGP G PG
Sbjct: 535 PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG 594

Query: 570 PPAVMPPTPPPQGEYLPDM-----GLGIDGVKPPHAYGAK--KGKNGGP 611
                    PP    LP +      +G  G  PP   G K  +G  G P
Sbjct: 595 GITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNP 643



 Score =  421 bits (1081), Expect = e-117
 Identities = 268/612 (43%), Positives = 303/612 (49%), Gaps = 141/612 (23%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGH-------GIPGIKGKPGPQGYPGV----------GK 159
           +G+ G  G PGP+G  GPPGLPG        G+PG  G PGPQG PG           G 
Sbjct: 77  KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136

Query: 160 PGMPGMPGKPGAMGMPGAKGEIGQ---------KGEIGPMGIPGPQGPPGPHGLPG-IGK 209
           PG PG+ G PG  G+PG KGE G          KG  G  G PG QG PGP G+PG IG 
Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 210 PGGPGL------PGQPGPKGD-----RGPKGLPGPQGLRGPKGDKGF------------- 245
           PG PGL      PG PGPKG+     +GPKG  G QGL+GP G  G              
Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256

Query: 246 ----GMPGAPGVKGPPGMHGPPGPVG----------LPGV----GKPGVTGFPGPQGPLG 287
               G+PG  G  GPPG+ GPPGP G           PG     GK G  G PG  G  G
Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 288 KPGAPGEPGPQGPIGVPGVQGPPGIPGIGKP--------GQDGIPGQPGFPGGKGEQGLP 339
            PG PGEPG  G  G  G  GPPG PG+  P        G+ G  G PG PG KGE+G P
Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 340 GLPGPPGLPGI---------GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG 390
           G+ GPPGLPG          G PGFPG +G +G  G PG   P       G PG+ G PG
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP-------GPPGLDGQPG 429

Query: 391 EPGLPGIPGPMGP----------PGAIGFPGPKGEGGIVGPQGPPGPKGEP-------GL 433
            PGLPG PGP GP          PG  G PG  G+ G+ G QG  G KG+        G+
Sbjct: 430 APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 434 QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG------VPGLPGVPGLLGPKGEPGI 487
            G PG+PG  G  GPPG  G PG  G KG+AG  G      +PG PG PG  G KGEPG 
Sbjct: 490 SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549

Query: 488 ----------PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG------LPGPPGFPG 531
                      G+ G  G PG+PG+ G  G  G PG+PGPKGEPG        GPPG PG
Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 532 I-GKPGVAGLHGPPG--KPGALGPQG------QPGLPGPPGPPGPPGPPAVMPPTPPPQG 582
           + G PG  G  GPPG   PG +G +G       PG PG PGP G PG     P  P   G
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 583 EYLPDMGLGIDG 594
               D  +G+ G
Sbjct: 670 NPGRDGDVGLPG 681



 Score =  420 bits (1080), Expect = e-117
 Identities = 255/533 (47%), Positives = 283/533 (53%), Gaps = 100/533 (18%)

Query: 118  GEQGPRGEPGPRGPPGP--------------PGLPGHGIPGIKGKPGPQGYPG------- 156
            GE+G +GEPG  GPPGP              PGLPG  IPG+ G  G QG PG       
Sbjct: 938  GEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPG--IPGVSGPKGYQGLPGDPGQPGL 995

Query: 157  VGKPGMPGMPGKPGAMGMPGAKGEIGQ---KGEIGPMGIPGPQG---PPGPHGLPGIGKP 210
             G+PG+PG PG  G  G+PG  G IG    KG IG MG PGPQG   PPGP G+PG  +P
Sbjct: 996  SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG--QP 1053

Query: 211  GGPGLPGQ-----------------PGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPG 252
            G PGLPGQ                 PGPKG+ G  G PG  G++G  GD G  G+PG PG
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPG 1113

Query: 253  VKGPPGMHG------PPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305
             KG PG+ G      PPGP G+ G  G PG+ G PGP G  G PG PG PG +G  G  G
Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173

Query: 306  VQGP------PGIPGIGKPGQDG---------------IPGQPGFPGGKGE---QGLPGL 341
            + GP      PG PG G PG  G               IPG PG PG KGE    G PG+
Sbjct: 1174 IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGV 1233

Query: 342  PGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM 401
             GPPG PG   P   GPKG+ G  G PG  G  G +GP G PG GG  GE G PG PG  
Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP 1293

Query: 402  GPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK 461
            G PG  G  GP G  G  G  G  G KG+PGL   PG PGF G  GP    G+PG  GP+
Sbjct: 1294 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL---PGVPGFPGMKGP---SGVPGSAGPE 1347

Query: 462  GEAGQKGVPGLPGVPG-------LLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGI 514
            GE G  G PG PG+PG       + G  G PGIPG  GL+G PG      P GP G PG 
Sbjct: 1348 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG------PQGPQGLPGP 1401

Query: 515  PGPKGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPG 566
             GP G+PG  G PGF G  G+ G  GL G PG  G  GP G  GL GPPGPPG
Sbjct: 1402 TGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  394 bits (1012), Expect = e-109
 Identities = 219/441 (49%), Positives = 249/441 (56%), Gaps = 62/441 (14%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPG------------------HGIPGIKGKPGPQGYPG--- 156
            G QG  G PGP G PG PG PG                   G+PG KG+PG  GYPG   
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 157  ----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPG 211
                VG PG+PG+PG PGA G PG  G  G  G  GP GI GP G PG  G PG +G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 212  GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGV------KGPPGMHGPPGP 265
             PG PG PG KG  G  G+PGP G +G  G  GFG PG PG+      KG  G+ G PG 
Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGN 1215

Query: 266  VGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIP 324
             GLPG  G+PG  GFPG QGP G PG+PG P  +GP G PG QGPPG PG+  PG +G P
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGL--PGPEGPP 1272

Query: 325  GQPGFPGGKGEQGLPGLPGPPGLPGI----------GKPGFPGPKGDRGMGGVPGALGPR 374
            G PG  G KGE+G PG PG PGLPG+          G PG PG  G +G  G+PG  G  
Sbjct: 1273 GLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP 1332

Query: 375  GEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV-GPQGPPGPKGEPGL 433
            G KGP G PG  GP GEPGL      +GPPG  G PGP G+  I+ G  GPPG  G+PGL
Sbjct: 1333 GMKGPSGVPGSAGPEGEPGL------IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL 1386

Query: 434  QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGL 493
            +G PG         P G +GLPGP GP G+ G+ G+PG  G  G  G  G PG PG +GL
Sbjct: 1387 KGLPG---------PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGL 1437

Query: 494  QGPPGIPGIGGPSGPIGPPGI 514
             GPPG  G+ GP GP G   +
Sbjct: 1438 DGPPGPDGLQGPPGPPGTSSV 1458



 Score =  388 bits (997), Expect = e-108
 Identities = 246/562 (43%), Positives = 282/562 (50%), Gaps = 133/562 (23%)

Query: 144 GIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG 203
           GIKG+ G +G+PG+   G PG+PG PG  G PG +G+ G  G      IPGP GP G  G
Sbjct: 42  GIKGEKGERGFPGL--EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIRG 93

Query: 204 LPGI-GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHG 261
            PG+ G PG PGLPG PG  G  GP+G+P   G  G KG++GF G PG PG++GPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIP---GCNGTKGERGFPGSPGFPGLQGPPGPPG 150

Query: 262 PPGPVGLPG-------VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG 314
            PG  G PG        G  G  G+PGP G  G PG  G PGP GP G PG+ GPPG PG
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 315 I---------------GKPGQDGIPGQPGFPG-------------GKGEQGLPGLPGPPG 346
           +               G+ G+ G+ G PG PG              KG+QGLPG  GPPG
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270

Query: 347 LPGI-GKPGFP-GPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP------ 398
            PGI G PG P G KG++G  G PG  G  G+ G  G PGI G PG+PG PG P      
Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330

Query: 399 ------GPMGPPGAI-------------------GFPGPKGEGGIVGPQGPPGPKGEPG- 432
                 GP GPPG +                   G PG KGE G  G QGPPG  G PG 
Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390

Query: 433 -LQGFPGKPGFLGEVGPPGMRGLPGPI--GPKGEAGQKGVPGLPGVPGLL---------- 479
            + G PG PGF GE G  G  G PG    GP G  GQ G PGLPG PG            
Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEI 450

Query: 480 ---GPKGEPGIPGDQGLQ-------------------------GPPGIPGIGGPSGPIGP 511
              GP G PG PGD+GLQ                         G PG+PG+ GP G +G 
Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 512 PGIPGPKGEPGLPGPPGFPGI----GKPGVAGLHGPPGK----PGALGPQGQPGLPGPPG 563
           PG  G KG+ G  GP G PGI    G PG  G  G PG     PG  G +G+ G PG PG
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG 570

Query: 564 PPGPPGPPAV--MPPTPPPQGE 583
            PG PG P    +P  P P+GE
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGE 592



 Score =  308 bits (788), Expect = 2e-83
 Identities = 207/462 (44%), Positives = 238/462 (51%), Gaps = 50/462 (10%)

Query: 235 GLRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPG 293
           G++G KG++GF G+ G PG+ G PG  GPPGP G  G    G+ G PGP+G  G PG PG
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKG--DDGIPGPPGPKGIRGPPGLPG 99

Query: 294 EPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GK 352
            PG  G  G+PG  G PG  GI  PG +G  G+ GFPG  G  GL G PGPPG+PG+ G+
Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGI--PGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 353 PG------FPGPKGDRGMGGVPGALG---PRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP 403
           PG       PGPKG+ G  G PG  G   P G  GPIG PG  G  G PG PG+PGP G 
Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 404 PGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP----------GKPGFLGEVGPPGMRG 453
            G + F GPKGE G  G QGPPGP G+   Q  P          G PG  G  GPPG+RG
Sbjct: 218 MG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276

Query: 454 LPGPIG-PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPP 512
            PGP G  KGE G++G PG  G PG  G  G+PGIPG   L G PG PG  G  G  G  
Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPG---LPGDPGYPGEPGRDGEKGQK 333

Query: 513 GIPGPKGEPGL--PGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP----- 565
           G  GP G PGL  P P     IG+ G  GL G PG+ G  G  G  G PG PGPP     
Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 566 GPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAF-----TA 620
           GPPGPP   P     +G+  P  G+ I G   P     + G  G P    PA      + 
Sbjct: 394 GPPGPPG-FPGERGQKGDEGPP-GISIPG---PPGLDGQPGAPGLPGPPGPAGPHIPPSD 448

Query: 621 ELTAPFPPVGAPVKFNKLLYNGRQNYNPQTG--IFTCEVPGV 660
           E+  P PP G P         G Q      G   F C   G+
Sbjct: 449 EICEPGPP-GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489



 Score =  271 bits (693), Expect = 2e-72
 Identities = 167/380 (43%), Positives = 197/380 (51%), Gaps = 50/380 (13%)

Query: 285 PLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----------GKPGQDGIPGQPGFPGGKG 334
           P  K    G  G +G  G PG++G PG+PG           G+ G DGIPG PG  G +G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 335 EQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG 393
             GLPG PG PGLPG+ G  G PGP+      G+PG  G +GE+G  G+PG  G  G PG
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQ------GIPGCNGTKGERGFPGSPGFPGLQGPPG 147

Query: 394 LPGIPGPMGPPGAI---GFPGPKGEGGIVGP---QGPPGPKGEPGLQGFPGKPGFLGEVG 447
            PGIPG  G PG+I     PGPKG  G  GP   QG PGP G PG  G PG PG +G  G
Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPG 207

Query: 448 PPGMRGLPGPI-----GPKGEAGQKGVPGLPGVPGLLG----------PKGEPGIPGDQG 492
           PPG+ G  G +     GPKGE G++G+ G PG PG +            KG+ G+PGD  
Sbjct: 208 PPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD-- 265

Query: 493 LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG----IGKPGVAGLHGPPGKPG 548
            +GPPG PGI GP GP  P G  G KGE G PG  G PG     G+PG+ GL G PG PG
Sbjct: 266 -RGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322

Query: 549 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN 608
             G  G+ G  G  GPPGPPG     P T    GE      +G+ G+          G  
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE---KGNIGLPGLPGEKGERGFPGIQ 379

Query: 609 GGPAYEMPAFTAELTAPFPP 628
           G P    P   A +  P PP
Sbjct: 380 GPPGLPGPPGAAVMGPPGPP 399


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  473 bits (1217), Expect = e-133
 Identities = 294/666 (44%), Positives = 337/666 (50%), Gaps = 139/666 (20%)

Query: 84   PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASL---RGEQGPRGEPGP-----------R 129
            P LP +   + P    G    P       L  L   +G+ GP G+PGP           +
Sbjct: 762  PGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQ 821

Query: 130  GPPGPPGLPG-------HGIPGIKGKPGP-----------QGYPGV-------GKPGMPG 164
            GPPGPPG+PG       HGIPG KG PGP           +G PG+       G PG PG
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 165  MPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKPGGPGLPGQPG 220
            +PGK GA G PG KGE+G    +GP G PGP G PG  G+PG+    G  G PGLPG  G
Sbjct: 882  LPGKAGASGFPGTKGEMGM---MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTG 938

Query: 221  PKGDRGPKGLPGPQG-----LRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPGVGKP 274
             KG +G  GLPGP G     L G KG+KG  G+PG PGV GP G  G PG  G PG+   
Sbjct: 939  EKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLS-- 996

Query: 275  GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----GKPGQDGIPGQPGFP 330
            G  G PGP GP G PG PG+PG  GP G+ G  G  G PG     G PG  G+PGQPG P
Sbjct: 997  GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056

Query: 331  GGKGEQG-----------LPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKG 378
            G  G++G           LPGLPGP G PG+ G PG PG KG  G  G+PG  G  G KG
Sbjct: 1057 GLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116

Query: 379  PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPG 438
              G PG  G PG PG  GI GP G PG  G PGP G GG  G  GPPG KG+PG  G PG
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG 1176

Query: 439  KPGFLGEVGPPGMRGLPGPIGPKGEAGQKG---VPGLPGVPGLLGPKGEPGIPGDQGLQG 495
              G  GE G PG  G PGP G  G +GQKG   +PG+PG PGL GPKGEPG  G  G+QG
Sbjct: 1177 PAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG 1235

Query: 496  PPGIPGIGGPS-----------------------GPIGPPGIPG------PKGEPGLPGP 526
            PPG PG  GP+                       GP GPPG+PG       KG PG PG 
Sbjct: 1236 PPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1295

Query: 527  PGFPGI----------------------------GKPGVAGLHGPPGKPGALGPQGQPGL 558
            PG PG+                            G PG  G+ GP G PG+ GP+G+PGL
Sbjct: 1296 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1355

Query: 559  PGPPGP---PGPPGPPAVMPPTPPPQGEYLPDM-GL-GIDGVKPPHAYGAKKGKNGGPAY 613
             GPPGP   PGP G   ++     P G  +P   GL G+ G + P       G  G P  
Sbjct: 1356 IGPPGPPGLPGPSGQSIIIKGDAGPPG--IPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR 1413

Query: 614  E-MPAF 618
              +P F
Sbjct: 1414 NGLPGF 1419



 Score =  469 bits (1208), Expect = e-132
 Identities = 287/610 (47%), Positives = 330/610 (54%), Gaps = 86/610 (14%)

Query: 37   PPQIP------PQMPPQIPQYQPLGQQVPH-MPLAK-DGLAMGKEMPHLQYGKEYPHLPQ 88
            PP +P      P  PP IP   P+GQ   H +P  K D    G ++P     +  P +P 
Sbjct: 812  PPGLPGIGVQGPPGPPGIPG--PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG 869

Query: 89   YMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKG 147
                I P    G   +P K         +GE G  G PGP   PGP G+PG  G+PG+KG
Sbjct: 870  APGPIGPP---GSPGLPGKAGASGFPGTKGEMGMMGPPGP---PGPLGIPGRSGVPGLKG 923

Query: 148  KPGPQGYPGV-------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPG 200
              G QG PG+       G  G PG+PG PG M  P   G  G+KGE G  GIPG  GP G
Sbjct: 924  DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD-PNLLGSKGEKGEPGLPGIPGVSGPKG 982

Query: 201  PHGLPGI-GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG----FGMPGAPGVKG 255
              GLPG  G+PG  G PG PGP G +G  GLPG  GL GP G KG     G PG  GV+G
Sbjct: 983  YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042

Query: 256  PPGMHGPPGPVGLPGV-------GKPGVT-----GFPGPQGPLGKPGAPGEPGPQGPIGV 303
            PPG  G PG  G PG+       G PG++     G PGP+G  G PG PG PG +G +G 
Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGD 1102

Query: 304  PGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGP 358
            PG+ G PG PG  G+PG  G PG PG PG KG  G PG PG PG PG     G PG PGP
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGP 1162

Query: 359  KGDRGMGGVPGALGPRGEKGPIGAPGIG--GPPGEPGL---------------PGIPGPM 401
             G++G  G  G  GP G+KG  G PG G  GPPG PGL               PG+PGP 
Sbjct: 1163 PGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPK 1222

Query: 402  GPPGAIGFPGPKGEGGIVGPQGPP--GPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIG 459
            G PG  GFPG +G  G  G  GP   GPKG PG QG PG+PGF G  GP G  GLPG  G
Sbjct: 1223 GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGG 1282

Query: 460  PKGEAGQKGVPGLPGVPGLLGPKGEPGI------PGDQGLQGPPGIPGIGGPSGPIGPPG 513
             KGE G  G PGLPG+PGL G +G PG+      PG  G++G PG+PG+ G  G  GP G
Sbjct: 1283 IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG 1342

Query: 514  IPG---PKGEPGLPGPPGFPGI-----------GKPGVAGLHGPPGKPGALGPQGQPGLP 559
            +PG   P+GEPGL GPPG PG+           G  G  G+ G PG  G  GPQG  GLP
Sbjct: 1343 VPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP 1402

Query: 560  GPPGPPGPPG 569
            GP GPPG PG
Sbjct: 1403 GPTGPPGDPG 1412



 Score =  468 bits (1204), Expect = e-132
 Identities = 279/591 (47%), Positives = 320/591 (54%), Gaps = 93/591 (15%)

Query: 111  IPLASLRGEQGPRGEPGPRGPPGPPGLPGH----------GIPGIKGKPG--------PQ 152
            IP   L G  GP+G PG  GPPG PG PG           G PG KG+PG        P 
Sbjct: 703  IPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPP 762

Query: 153  GYPGV----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG-----PQG 197
            G PG           G PG PG PG+ G  G+PG KG++G  G+ GPMG PG      QG
Sbjct: 763  GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQG 822

Query: 198  PPGPHGLPG-IGKPGGPGLPGQ-----------PGPKGDRGPKGLPGPQGLRGPKGDKGF 245
            PPGP G+PG IG+PG  G+PG+           PGP G+RG  G+PG  G  GP G  G 
Sbjct: 823  PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGL 882

Query: 246  ----GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGP 300
                G  G PG KG  GM GPPGP G  G+ G+ GV G  G  G  G+PG PG  G +G 
Sbjct: 883  PGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGS 942

Query: 301  IGVPGVQGPPG------IPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKP 353
             G PG+ GPPG      +   G+ G+ G+PG PG  G KG QGLPG PG PGL G  G P
Sbjct: 943  KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP 1002

Query: 354  GFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPK 413
            G PGPKG+ G+ G PG +GP G KG IG  G  GP G  G PG  G  G PG+ G PG K
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062

Query: 414  GEGG-----IVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG 468
            G+ G      +G  G PGPKGEPGL G+PG PG  G VG PG+ GLPG  G KG+ G  G
Sbjct: 1063 GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122

Query: 469  VPGLPGVP---GLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPP---GIPGP---KG 519
             PG PG P   G+ GP G PG+PG+ G  G  G PG  GP G  G P   GIPGP   KG
Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG 1182

Query: 520  EPGL-----PGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQ------PGLPGPPGPPGP 567
            EPG      PGPPG PG+ G+ G  GL G PG PG  GP+G+      PG+ GPPGPPG 
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242

Query: 568  PGPPAVMPP-TPPPQGEYLPDMGLGIDGVKPPH------AYGAKKGKNGGP 611
            PGP    P   P PQG   P    G  G+  P         G  KG+ G P
Sbjct: 1243 PGPALEGPKGNPGPQG---PPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNP 1290



 Score =  462 bits (1188), Expect = e-130
 Identities = 285/614 (46%), Positives = 334/614 (54%), Gaps = 77/614 (12%)

Query: 32   GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMK 91
            G+  LP  I P  PP      P+G++         G+A     P +   K  P       
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPVGEK------GIQGVAGNPGQPGIPGPKGDPG------ 656

Query: 92   EIQPAPRMGKEAVP-KKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH----GIPGI- 145
              Q   + GK  +P   G++       G+ G  G+PG  G PG PG+PG     GIPGI 
Sbjct: 657  --QTITQPGKPGLPGNPGRD-------GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707

Query: 146  -KGKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG 203
              G PGP+G+PG+ G PG PG PG+ G  G PG  G  G KGE G   +PGP GPPG  G
Sbjct: 708  LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG-FALPGPPGPPGLPG 766

Query: 204  LPG-IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHG 261
              G +G  G  G PG PGP G  G  GLPGP+G  GP G  G  G PG PG+    G+ G
Sbjct: 767  FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI----GVQG 822

Query: 262  PPGPVGLPG-VGKPGVTGFPGPQGPLGKPG--APGEPGPQGPIGVPGVQGPPGIPGIGKP 318
            PPGP G+PG +G+PG+ G PG +G  G PG   PG PG +G  G+PG  GP G P  G P
Sbjct: 823  PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSP 880

Query: 319  GQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEK 377
            G  G  G  GFPG KGE G+ G PGPPG  GI G+ G PG KGD G+ G PG  GP GEK
Sbjct: 881  GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 378  GPIGAPGIGGPP--------------GEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG 423
            G  G PG+ GPP              GEPGLPGIPG  GP G  G PG  G+ G+ G  G
Sbjct: 941  GSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG 1000

Query: 424  PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKG 483
             PGP G  G  G PG+PG    +GPPG++G  G +G  G  G +G PG  GVP   G  G
Sbjct: 1001 LPGPPGPKGNPGLPGQPGL---IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP---GQPG 1054

Query: 484  EPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHG 542
             PG+PG +G +G PGI         IG PG+PGPKGEPGLPG PG PGI G  G  GL G
Sbjct: 1055 SPGLPGQKGDKGDPGI-------SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 543  PPGKPGALGPQGQPGLPGPPGPPGPPGPPAVM--PPTPPPQGEYLPDMGLGIDGVKPPHA 600
             PG PGA   +GQPGLPG PG PGPPGP  +   P  P   GE  P  G G  G   P  
Sbjct: 1108 LPGTPGA---KGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164

Query: 601  YGAKKGKNG--GPA 612
               K G++G  GPA
Sbjct: 1165 EKGKPGQDGIPGPA 1178



 Score =  457 bits (1176), Expect = e-128
 Identities = 274/596 (45%), Positives = 310/596 (52%), Gaps = 110/596 (18%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKP---- 149
            P  + G   +P     +     +GE+G  G  GP+G PG PG PG  G PG KG+P    
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 150  ---------GPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQ---KGEIGPMGIPGPQ 196
                     G  G PG  G PG+PG PG+ G  G+PG KGE G    KGE GP G PG  
Sbjct: 552  TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 197  GPP---GPHGLPGIGKP------------GGPGLPGQPGPKGDRGPK-GLPGPQGLRG-P 239
            G P   GP G PG G P            G PG PG PGPKGD G     PG  GL G P
Sbjct: 612  GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 240  KGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV------GKPGVTGFPGPQGPLGKPGAPG 293
              D   G+PG PG+ G PG+ G PG  G PG+      G PG  GFPG  GP G PG PG
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 294  EPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG-IGK 352
              G +GP G PG  GP G PG   PG  G PG PGF G  G +G  G PGPPG PG  G 
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 353  PGFPGPKGDRGMGGVPGAL--------------GPRGEKGPIGAPGIGGPPGE------- 391
             G PGPKGD G  G PG +              GP G  GPIG PG+ G PGE       
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 392  -------------PGLPGIPGPMGPP---------GAIGFPGPKGEGGIVGPQGPPGP-- 427
                         PG+PG PGP+GPP         GA GFPG KGE G++GP GPPGP  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 428  ----------KGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK-----GEAGQKGVPGL 472
                      KG+ GLQG PG PG  GE G  G  GLPGP GP      G  G+KG PGL
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 473  PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG- 531
            PG+PG+ GPKG  G+PGD G  G  G PG+ GP GP G PG+P   G+PGL GPPG  G 
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP---GQPGLIGPPGLKGT 1028

Query: 532  ---IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV-MPPTPPPQGE 583
               +G PG  G+ GPPG  G  G  G PGLPG  G  G PG  ++ +P  P P+GE
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084



 Score =  451 bits (1161), Expect = e-127
 Identities = 266/528 (50%), Positives = 295/528 (55%), Gaps = 87/528 (16%)

Query: 118  GEQGPRGEPGPRGPPGP--------------PGLPGHGIPGIKGKPGPQGYPG------- 156
            GE+G +GEPG  GPPGP              PGLPG  IPG+ G  G QG PG       
Sbjct: 938  GEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPG--IPGVSGPKGYQGLPGDPGQPGL 995

Query: 157  VGKPGMPGMPGKPGAMGMPGAKGEIGQ---KGEIGPMGIPGPQG---PPGPHGLPGIGKP 210
             G+PG+PG PG  G  G+PG  G IG    KG IG MG PGPQG   PPGP G+PG  +P
Sbjct: 996  SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG--QP 1053

Query: 211  GGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGP------PGMHGPP 263
            G PGLPGQ G KGD G   + G  GL GPKG+ G  G PG PG+KG       PG+ G P
Sbjct: 1054 GSPGLPGQKGDKGDPGISSI-GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 264  GPVGLPGV-GKPGVTGFPGPQG---PLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPG 319
            G  G PG+ G PG  G PGP+G   P G PG PGEPGP G  G PG  GPPG  G  KPG
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG--KPG 1170

Query: 320  QDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-------------GKPGFPGPKGDRGMGG 366
            QDGIPG  G  G  G+ G  G PGPPGLPG+             G PG PGPKG+ G  G
Sbjct: 1171 QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229

Query: 367  VPGALGPRGE--------KGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGI 418
             PG  GP G         +GP G PG  GPPG PG  G+PGP GPPG  G  G KGE G 
Sbjct: 1230 FPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGN 1289

Query: 419  VGPQGPPG------PKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGL 472
             G  G PG       +G PGLQG PG+PG  G  G PG+ G+PG  G KG +G  G  G 
Sbjct: 1290 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP 1349

Query: 473  PGVPGLLGPKGEPGIPGDQGLQ-------GPPGIPG---IGGPSGPIGPPGIPGPKGEPG 522
             G PGL+GP G PG+PG  G         GPPGIPG   + G  GP GP G+PGP G PG
Sbjct: 1350 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1409

Query: 523  LPGPPGFPGI----GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPG 566
             PG  G PG     G+ G  GL G PG  G  GP G  GL GPPGPPG
Sbjct: 1410 DPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  447 bits (1150), Expect = e-125
 Identities = 304/720 (42%), Positives = 357/720 (49%), Gaps = 161/720 (22%)

Query: 36  LPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQP 95
           +P  I P  PP +    P G   P +P  K  + +  + P  + G++    P       P
Sbjct: 190 IPGPIGPPGPPGL--MGPPGP--PGLPGPKGNMGLNFQGPKGEKGEQGLQGP-------P 238

Query: 96  APRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPP---GPPGLPG--HGIPGIKGKPG 150
            P      + ++ + I +   +G+QG  G+ GP GPP   GPPG PG   G  G +G+PG
Sbjct: 239 GP---PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295

Query: 151 PQGYPGV----GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG 206
            +G PG     G+PG+PG+PG PG  G PG  GE GQKG+ GP G PG   P    G+  
Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT- 354

Query: 207 IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPV 266
           IG+ G  GLPG PG KG+RG  G+ GP GL GP G    G PG PG  G  G  G  GP 
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414

Query: 267 GL-----PGV-GKPGVTGFPGPQGPL----------------GKPGAPGEPGPQGPIGV- 303
           G+     PG+ G+PG  G PGP GP                 G PG+PG+ G QG  GV 
Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474

Query: 304 ------------PGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGE---------QGLPGLP 342
                        G+ GPPG PG+  PG  G PG  GFPG KGE         +GLPG+P
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGL--PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 343 GPPGLPGI----GKPG----FPGPKGDR------------------GMGGVPGALGPRGE 376
           G PG PG     G+PG    FPG KGD+                  G  G+PG  GP+GE
Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE 592

Query: 377 KGPIGAPGIGGPPGEPGLPGIP---GPMGPPGAIGFPGPKGEGGI------VGPQGPPGP 427
            G I   G  GPPG PGLPG+P   GPMGPPG  G PGP GE GI       G  G PGP
Sbjct: 593 PGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 428 KG-------EPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV--PGL 478
           KG       +PG  G PG PG  G+VG PG  GLPG  G  G  G KG PG+PG+  PG 
Sbjct: 652 KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 479 LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG--LPGPPGFPGI---- 532
            GPKG PGIPG     G PG PG  G  GP GPPG PGPKGEPG  LPGPPG PG+    
Sbjct: 712 PGPKGFPGIPGP---PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768

Query: 533 ---------------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP-----GPPGPPA 572
                          G PG  GL G PG  G +GP GQPG  GPPG P     GPPGPP 
Sbjct: 769 GALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 573 VMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
           +  P   P        GL        H    +KG  G P  ++P    E  +P  P GAP
Sbjct: 829 IPGPIGQP--------GL--------HGIPGEKGDPGPPGLDVPGPPGERGSPGIP-GAP 871



 Score =  437 bits (1123), Expect = e-122
 Identities = 292/671 (43%), Positives = 330/671 (49%), Gaps = 151/671 (22%)

Query: 97   PRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG---------HGIPGIKG 147
            PR G      +   I L  L GE+G RG PG +GPPG PG PG          G PG +G
Sbjct: 347  PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406

Query: 148  KPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKG----------EIGQKGEIGPMGIPGPQ- 196
            + G +G PG+  PG PG+ G+PGA G+PG  G          EI + G  GP G PG + 
Sbjct: 407  QKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKG 466

Query: 197  ------------------------GPPGPHGLPGI-GKPGGPGLPGQPGPKGD---RGPK 228
                                    GPPG  GLPG+ G PG  G PGQ G KG     GPK
Sbjct: 467  LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526

Query: 229  GLPGPQG-------------------LRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGL 268
            GLPG  G                     G KGDKG  G PGAPG+ G PG  G  G  GL
Sbjct: 527  GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586

Query: 269  PG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP------GIPGI-GKPGQ 320
            PG  G+PG   F G +GP G PG PG PG  GP+G PG  GPP      GI G+ G PGQ
Sbjct: 587  PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQ 645

Query: 321  DGI-------------PGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367
             GI             PG+PG PG  G  G  GLPG PGLP  G+PG PG  G +G  G+
Sbjct: 646  PGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP--GQPGLPGIPGSKGEPGI 703

Query: 368  PGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGP 427
            PG +G  G  GP G PGI GPPG PG PG  G  GPPG  GFPGPKGE G   P GPPGP
Sbjct: 704  PG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP-GPPGP 761

Query: 428  KGEPGLQGFPGKPGFLGEVGPP------GMRGLPGP---IGPKGEAGQKGVPGLPGV--- 475
             G PG +G  G  G  G  GPP      G+ GLPGP   +GP G+ G  G PGLPG+   
Sbjct: 762  PGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQ 821

Query: 476  -----PGLLGPKGEP---GIPGDQGLQGPPGI-----------PGIGGPSGPIGPP---- 512
                 PG+ GP G+P   GIPG++G  GPPG+           PGI G  GPIGPP    
Sbjct: 822  GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 513  --------GIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGP--- 561
                    G PG KGE G+ GPPG P  G  G+ G  G PG  G  G QGQPGLPGP   
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPP--GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 562  ---PGPPGPPGPPAVMPPTPPPQGEYLPDMGL-GIDGVKPPHAYGAKKGKNGGPAYEMPA 617
                G PG PGPP  M P          + GL GI GV  P  Y    G  G      P 
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPG-----QPG 994

Query: 618  FTAELTAPFPP 628
             + +   P PP
Sbjct: 995  LSGQPGLPGPP 1005



 Score =  427 bits (1097), Expect = e-119
 Identities = 263/596 (44%), Positives = 304/596 (51%), Gaps = 125/596 (20%)

Query: 108 GKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-------------HGIP------GIKGK 148
           G +   + ++GE+G RG PG  G PG PG PG              GIP      GI+G 
Sbjct: 35  GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP 94

Query: 149 PGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI 207
           PG  G+PG  G PGMPG  G PG  G+PG  G  G++G  G  G PG QGPPGP G+PG+
Sbjct: 95  PGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM 154

Query: 208 -GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGP 265
            G+PG   +   PGPKG+ G  G PG QGL GP G  G  G PG PG+ GPPG  G PGP
Sbjct: 155 KGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 266 VGLPGVGKPGVTGFPGPQGPLGKPGAPGE-------------------PGPQGPIGVPGV 306
            G  G+   G  G  G QG  G PG PG+                   PG +GP G PG+
Sbjct: 215 KGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGI 274

Query: 307 QGPPGIPG--IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPKG 360
           +GPPG PG   G+ G+ G PG+ G PG  GE G PG+PG PG PG     G+ G  G KG
Sbjct: 275 RGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKG 334

Query: 361 DRGMGGVPGALGPR-------GEKGPIGAPGIGGPPGEPGLPGIPGP-----------MG 402
           D G  G PG + PR       GEKG IG PG+ G  GE G PGI GP           MG
Sbjct: 335 DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMG 394

Query: 403 PPGAIGFPGPKGEGGIVGP-----QGPPGPKGEPGLQGFPGKPGFLG----------EVG 447
           PPG  GFPG +G+ G  GP      GPPG  G+PG  G PG PG  G          E G
Sbjct: 395 PPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454

Query: 448 PPGMRGLPGPIGPKGEAGQK----------------GVPGLPGVPGLLGPKGEPGIPGDQ 491
           PPG  G PG  G +GE G K                G PG PG+PGL GP G  G PG +
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514

Query: 492 ------GLQGPPGIPGI-GGPSGPIGP------------PGIPGPKGEPGLPGPPGFPGI 532
                 G  GP G+PGI G P  P  P            PG+ G KGE G PG PG PG+
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 533 ----GKPGVAGLHGPPGKPGAL------GPQGQPGLPGPPGPPGPPGPPAVMPPTP 578
               G+ G+ GL GP G+PG +      GP G PGLPG PG  GP GPP   PP P
Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGP 630



 Score =  422 bits (1085), Expect = e-118
 Identities = 263/589 (44%), Positives = 299/589 (50%), Gaps = 99/589 (16%)

Query: 116 LRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMG 173
           L G  GP G PGPRG  G  G+PG  G  GI+G PG  G+PG  G PGMPG  G PG  G
Sbjct: 61  LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG 120

Query: 174 MPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGPKGLPG 232
           +PG  G  G++G  G  G PG QGPPGP G+PG+ G+PG   +   PGPKG+ G  G PG
Sbjct: 121 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 233 PQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGA 291
            QGL GP G  G  G PG PG+ GPPG  G PGP G  G+   G  G  G QG  G PG 
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 292 PGE-------------------PGPQGPIGVPGVQGPPGIPG--IGKPGQDGIPGQPGFP 330
           PG+                   PG +GP G PG++GPPG PG   G+ G+ G PG+ G P
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 331 GGKGEQGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPR-------GEKGP 379
           G  GE G PG+PG PG PG     G+ G  G KGD G  G PG + PR       GEKG 
Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 380 IGAPGIGGPPGEPGLPGIPGP-----------MGPPGAIGFPGPKGEGGIVGPQG----- 423
           IG PG+ G  GE G PGI GP           MGPPG  GFPG +G+ G  GP G     
Sbjct: 361 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG 420

Query: 424 PPGPKGEPGLQGFPGKPGFLG----------EVGPPGMRGLPGPIGPKGEAGQKG----- 468
           PPG  G+PG  G PG PG  G          E GPPG  G PG  G +GE G KG     
Sbjct: 421 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 480

Query: 469 -----------VPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGP 517
                       PG PG+PGL GP G  G PG +G +G        G +GP G PGIPG 
Sbjct: 481 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ------AGATGPKGLPGIPGA 534

Query: 518 KGEPGLPGPPG-------FPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPG 569
            G PG PG  G       FPG+ G  G  G  G PG PG  G  GQ GLPG PGP G PG
Sbjct: 535 PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG 594

Query: 570 PPAVMPPTPPPQGEYLPDM-----GLGIDGVKPPHAYGAK--KGKNGGP 611
                    PP    LP +      +G  G  PP   G K  +G  G P
Sbjct: 595 GITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNP 643



 Score =  421 bits (1081), Expect = e-117
 Identities = 268/612 (43%), Positives = 303/612 (49%), Gaps = 141/612 (23%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGH-------GIPGIKGKPGPQGYPGV----------GK 159
           +G+ G  G PGP+G  GPPGLPG        G+PG  G PGPQG PG           G 
Sbjct: 77  KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136

Query: 160 PGMPGMPGKPGAMGMPGAKGEIGQ---------KGEIGPMGIPGPQGPPGPHGLPG-IGK 209
           PG PG+ G PG  G+PG KGE G          KG  G  G PG QG PGP G+PG IG 
Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 210 PGGPGL------PGQPGPKGD-----RGPKGLPGPQGLRGPKGDKGF------------- 245
           PG PGL      PG PGPKG+     +GPKG  G QGL+GP G  G              
Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256

Query: 246 ----GMPGAPGVKGPPGMHGPPGPVG----------LPGV----GKPGVTGFPGPQGPLG 287
               G+PG  G  GPPG+ GPPGP G           PG     GK G  G PG  G  G
Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 288 KPGAPGEPGPQGPIGVPGVQGPPGIPGIGKP--------GQDGIPGQPGFPGGKGEQGLP 339
            PG PGEPG  G  G  G  GPPG PG+  P        G+ G  G PG PG KGE+G P
Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 340 GLPGPPGLPGI---------GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG 390
           G+ GPPGLPG          G PGFPG +G +G  G PG   P       G PG+ G PG
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP-------GPPGLDGQPG 429

Query: 391 EPGLPGIPGPMGP----------PGAIGFPGPKGEGGIVGPQGPPGPKGEP-------GL 433
            PGLPG PGP GP          PG  G PG  G+ G+ G QG  G KG+        G+
Sbjct: 430 APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 434 QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG------VPGLPGVPGLLGPKGEPGI 487
            G PG+PG  G  GPPG  G PG  G KG+AG  G      +PG PG PG  G KGEPG 
Sbjct: 490 SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549

Query: 488 ----------PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG------LPGPPGFPG 531
                      G+ G  G PG+PG+ G  G  G PG+PGPKGEPG        GPPG PG
Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 532 I-GKPGVAGLHGPPG--KPGALGPQG------QPGLPGPPGPPGPPGPPAVMPPTPPPQG 582
           + G PG  G  GPPG   PG +G +G       PG PG PGP G PG     P  P   G
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 583 EYLPDMGLGIDG 594
               D  +G+ G
Sbjct: 670 NPGRDGDVGLPG 681



 Score =  395 bits (1015), Expect = e-110
 Identities = 220/442 (49%), Positives = 249/442 (56%), Gaps = 61/442 (13%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPG------------------HGIPGIKGKPGPQGYPG--- 156
            G QG  G PGP G PG PG PG                   G+PG KG+PG  GYPG   
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 157  ----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPG 211
                VG PG+PG+PG PGA G PG  G  G  G  GP GI GP G PG  G PG +G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 212  GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGV------KGPPGMHGPPGP 265
             PG PG PG KG  G  G+PGP G +G  G  GFG PG PG+      KG  G+ G PG 
Sbjct: 1156 HPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGN 1215

Query: 266  VGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGI 323
             GLPG  G+PG  GFPG QGP G PG+PG P  +GP G PG QGPPG PG  G PG +G 
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGFQGLPGPEGP 1274

Query: 324  PGQPGFPGGKGEQGLPGLPGPPGLPGI----------GKPGFPGPKGDRGMGGVPGALGP 373
            PG PG  G KGE+G PG PG PGLPG+          G PG PG  G +G  G+PG  G 
Sbjct: 1275 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1334

Query: 374  RGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV-GPQGPPGPKGEPG 432
             G KGP G PG  GP GEPGL      +GPPG  G PGP G+  I+ G  GPPG  G+PG
Sbjct: 1335 PGMKGPSGVPGSAGPEGEPGL------IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG 1388

Query: 433  LQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQG 492
            L+G PG         P G +GLPGP GP G+ G+ G+PG  G  G  G  G PG PG +G
Sbjct: 1389 LKGLPG---------PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1439

Query: 493  LQGPPGIPGIGGPSGPIGPPGI 514
            L GPPG  G+ GP GP G   +
Sbjct: 1440 LDGPPGPDGLQGPPGPPGTSSV 1461



 Score =  388 bits (997), Expect = e-108
 Identities = 246/562 (43%), Positives = 282/562 (50%), Gaps = 133/562 (23%)

Query: 144 GIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG 203
           GIKG+ G +G+PG+   G PG+PG PG  G PG +G+ G  G      IPGP GP G  G
Sbjct: 42  GIKGEKGERGFPGL--EGHPGLPGFPGPEGPPGPRGQKGDDG------IPGPPGPKGIRG 93

Query: 204 LPGI-GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHG 261
            PG+ G PG PGLPG PG  G  GP+G+P   G  G KG++GF G PG PG++GPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIP---GCNGTKGERGFPGSPGFPGLQGPPGPPG 150

Query: 262 PPGPVGLPG-------VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG 314
            PG  G PG        G  G  G+PGP G  G PG  G PGP GP G PG+ GPPG PG
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 315 I---------------GKPGQDGIPGQPGFPG-------------GKGEQGLPGLPGPPG 346
           +               G+ G+ G+ G PG PG              KG+QGLPG  GPPG
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270

Query: 347 LPGI-GKPGFP-GPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP------ 398
            PGI G PG P G KG++G  G PG  G  G+ G  G PGI G PG+PG PG P      
Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330

Query: 399 ------GPMGPPGAI-------------------GFPGPKGEGGIVGPQGPPGPKGEPG- 432
                 GP GPPG +                   G PG KGE G  G QGPPG  G PG 
Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390

Query: 433 -LQGFPGKPGFLGEVGPPGMRGLPGPI--GPKGEAGQKGVPGLPGVPGLL---------- 479
            + G PG PGF GE G  G  G PG    GP G  GQ G PGLPG PG            
Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEI 450

Query: 480 ---GPKGEPGIPGDQGLQ-------------------------GPPGIPGIGGPSGPIGP 511
              GP G PG PGD+GLQ                         G PG+PG+ GP G +G 
Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 512 PGIPGPKGEPGLPGPPGFPGI----GKPGVAGLHGPPGK----PGALGPQGQPGLPGPPG 563
           PG  G KG+ G  GP G PGI    G PG  G  G PG     PG  G +G+ G PG PG
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG 570

Query: 564 PPGPPGPPAV--MPPTPPPQGE 583
            PG PG P    +P  P P+GE
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGE 592



 Score =  308 bits (788), Expect = 2e-83
 Identities = 207/462 (44%), Positives = 238/462 (51%), Gaps = 50/462 (10%)

Query: 235 GLRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPG 293
           G++G KG++GF G+ G PG+ G PG  GPPGP G  G    G+ G PGP+G  G PG PG
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKG--DDGIPGPPGPKGIRGPPGLPG 99

Query: 294 EPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GK 352
            PG  G  G+PG  G PG  GI  PG +G  G+ GFPG  G  GL G PGPPG+PG+ G+
Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGI--PGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 353 PG------FPGPKGDRGMGGVPGALG---PRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP 403
           PG       PGPKG+ G  G PG  G   P G  GPIG PG  G  G PG PG+PGP G 
Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 404 PGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP----------GKPGFLGEVGPPGMRG 453
            G + F GPKGE G  G QGPPGP G+   Q  P          G PG  G  GPPG+RG
Sbjct: 218 MG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276

Query: 454 LPGPIG-PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPP 512
            PGP G  KGE G++G PG  G PG  G  G+PGIPG   L G PG PG  G  G  G  
Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPG---LPGDPGYPGEPGRDGEKGQK 333

Query: 513 GIPGPKGEPGL--PGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP----- 565
           G  GP G PGL  P P     IG+ G  GL G PG+ G  G  G  G PG PGPP     
Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 566 GPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAF-----TA 620
           GPPGPP   P     +G+  P  G+ I G   P     + G  G P    PA      + 
Sbjct: 394 GPPGPPG-FPGERGQKGDEGPP-GISIPG---PPGLDGQPGAPGLPGPPGPAGPHIPPSD 448

Query: 621 ELTAPFPPVGAPVKFNKLLYNGRQNYNPQTG--IFTCEVPGV 660
           E+  P PP G P         G Q      G   F C   G+
Sbjct: 449 EICEPGPP-GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489



 Score =  271 bits (693), Expect = 2e-72
 Identities = 167/380 (43%), Positives = 197/380 (51%), Gaps = 50/380 (13%)

Query: 285 PLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----------GKPGQDGIPGQPGFPGGKG 334
           P  K    G  G +G  G PG++G PG+PG           G+ G DGIPG PG  G +G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 335 EQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG 393
             GLPG PG PGLPG+ G  G PGP+      G+PG  G +GE+G  G+PG  G  G PG
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQ------GIPGCNGTKGERGFPGSPGFPGLQGPPG 147

Query: 394 LPGIPGPMGPPGAI---GFPGPKGEGGIVGP---QGPPGPKGEPGLQGFPGKPGFLGEVG 447
            PGIPG  G PG+I     PGPKG  G  GP   QG PGP G PG  G PG PG +G  G
Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPG 207

Query: 448 PPGMRGLPGPI-----GPKGEAGQKGVPGLPGVPGLLG----------PKGEPGIPGDQG 492
           PPG+ G  G +     GPKGE G++G+ G PG PG +            KG+ G+PGD  
Sbjct: 208 PPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD-- 265

Query: 493 LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG----IGKPGVAGLHGPPGKPG 548
            +GPPG PGI GP GP  P G  G KGE G PG  G PG     G+PG+ GL G PG PG
Sbjct: 266 -RGPPGPPGIRGPPGP--PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322

Query: 549 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN 608
             G  G+ G  G  GPPGPPG     P T    GE      +G+ G+          G  
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE---KGNIGLPGLPGEKGERGFPGIQ 379

Query: 609 GGPAYEMPAFTAELTAPFPP 628
           G P    P   A +  P PP
Sbjct: 380 GPPGLPGPPGAAVMGPPGPP 399


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  456 bits (1173), Expect = e-128
 Identities = 285/653 (43%), Positives = 332/653 (50%), Gaps = 128/653 (19%)

Query: 62   PLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQG 121
            P   +GL      P  Q  + +P  P      +P     K AV + G   P     G  G
Sbjct: 647  PPGAEGLPGSPGFPGPQGDRGFPGTPG-----RPGLPGEKGAVGQPGIGFP-----GPPG 696

Query: 122  PRGE---PGPRGPPGPPGLPG-HGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGA 177
            P+G    PG  GPPG PG PG +G+PG  G  G +G PGVG PG+ G+PG PG  G PG 
Sbjct: 697  PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756

Query: 178  KGEIG------QKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGL--PGQPGPKGDRGPK 228
            KG IG      + G IGP G+ G +G PGP GLPG +G PG PG+  PG  GP G +GP 
Sbjct: 757  KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816

Query: 229  GLPGPQGLRGPKGDKGF---GMPGAPGVKGPPGMHGPPGPVGLPGV----GKPGVTGFPG 281
            GL GP G++G KG  GF    MPG  G KG  G+ G  G  GLPG+    G PG+ GFPG
Sbjct: 817  GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPG 876

Query: 282  PQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGL 341
             +G +G  G PG+PG  GP+G PG+ G  G  G   PG  G  G PG  G KG+ GLPG 
Sbjct: 877  SKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGF--PGSSGPRGDPGLKGDKGDVGLPGK 934

Query: 342  PGP---------------------------------PGLPGI-------GKPGFPGPKGD 361
            PG                                  PG PG+       G+PG PGPKGD
Sbjct: 935  PGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGD 994

Query: 362  RGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGP 421
             G+ G PGA G  G KG +G  G+ G PGE G+PGIPGP G PG  G  G KGE G  GP
Sbjct: 995  PGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGP 1054

Query: 422  QGPP-----GPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP 476
             G       G KG+ G+ GFPG PG  GE G  G+ G+PG  G KG  G  G PG PG+P
Sbjct: 1055 PGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLP 1114

Query: 477  GLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGP---------PGIPGPKGEPGLPGP- 526
            G  G KG PG+ G  G++G  G+PG  GP+GP G          PG  G KGEPGLPG  
Sbjct: 1115 GEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRG 1174

Query: 527  -PGFPG----------IGKPGVAGLHGPPGKPGAL------GPQGQPGLPGPP------- 562
             PGFPG          +G PG+AG  G PG  G        GPQGQPGLPG P       
Sbjct: 1175 FPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGP 1234

Query: 563  ----GPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP 611
                GP G PG P +  P  PP    LP    GIDGVK        KG  G P
Sbjct: 1235 KGDRGPQGQPGLPGLPGPMGPPG---LP----GIDGVK------GDKGNPGWP 1274



 Score =  450 bits (1158), Expect = e-126
 Identities = 284/676 (42%), Positives = 342/676 (50%), Gaps = 139/676 (20%)

Query: 34   KPLPPQIPPQM-PPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKE 92
            +P PP +P  +  P +P   P G + P       GL+     P ++  K +P  P     
Sbjct: 783  EPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLS---GPPGIKGEKGFPGFPGLD-- 837

Query: 93   IQPAPR--MGKEAVPKKGKEIPLASLRGEQGP---------RGEPGPRGPPGPPGLPGH- 140
              P P+   G + +P    +  L  L G+QG          +GE G  G PG PG PG  
Sbjct: 838  -MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPV 896

Query: 141  GIPGIKGKPGPQGYPGV----GKPGMPG------MPGKPGAM------GMPGAKGEIGQK 184
            G PG+ G+ G  G+PG     G PG+ G      +PGKPG+M       M G KG+ G+K
Sbjct: 897  GAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEK 956

Query: 185  GEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244
            G+IGP+G  G +G PG  G+PG  K G  G PGQPGPKGD G  G PG  GL GPKG  G
Sbjct: 957  GQIGPIGEKGSRGDPGTPGVPG--KDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVG 1014

Query: 245  -FGMPGAPGVKGPPGMHGPPGPVGLPG---------------VGKPGVTGFPGPQGPLGK 288
              G+PG PG KG PG+ GP G  GLPG               +G PG+ G  G QG  G 
Sbjct: 1015 GMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGF 1074

Query: 289  PGAPGEPGPQGPIGVPGVQGPPGIPG----IGKPGQDGIPGQPG---------FPGGKGE 335
            PG+PGE G +G IG+PG+ G PG+ G    +G PG  G+PG+ G          PG KGE
Sbjct: 1075 PGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGE 1134

Query: 336  QGLPGLPGP------------------------PGLPGIGKPGFPGPKGDRG-------- 363
             GLPG PGP                        PGLPG G PGFPG KGD+G        
Sbjct: 1135 AGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFP 1194

Query: 364  -MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPG-----------PMGPPGAIGFPG 411
             + G PG  G +GE+G +G PG   P G+PGLPG PG           P G PG  G PG
Sbjct: 1195 GLAGSPGIPGSKGEQGFMGPPG---PQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPG 1251

Query: 412  PKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPG 471
            P G  G+ G  G  G KG PG   +PG PG  G  G PG +G+PG  G  G  G KG  G
Sbjct: 1252 PMGPPGLPGIDGVKGDKGNPG---WPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMG 1308

Query: 472  LPGVPGLLGPKGEPG---IPGDQGLQGPPGIPGIGGPSGPIGP-------PGIPGPKGEP 521
             PGVPG  GPKG PG   I GDQG QG PG  G+ GP GP GP       PG+PGP+G P
Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPP 1368

Query: 522  GL------PGPPGFPGI-------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPP 568
            GL      PGP G  G+       G PG+ G  G PG+ G +GP G  G  G PGPPGP 
Sbjct: 1369 GLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPD 1428

Query: 569  GPPAVMPPTPPPQGEY 584
            G P  M P   P  ++
Sbjct: 1429 GLPGSMGPPGTPSVDH 1444



 Score =  422 bits (1086), Expect = e-118
 Identities = 261/581 (44%), Positives = 289/581 (49%), Gaps = 101/581 (17%)

Query: 117 RGEQGPRG------EPGPRGPP-----GPPGLPGH---------------------GIPG 144
           RGE GP+G      +PGP G P     G PG PG                      G+PG
Sbjct: 355 RGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPG 414

Query: 145 IKGKPGPQGYPGVG------KPGMPGMPGKPGAMGMPGAKGEIGQKGEIGP----MGIPG 194
             G PGP G PG        +PG PG  G PG  G PG  GEIG+KG+ G       I G
Sbjct: 415 PPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDG 474

Query: 195 PQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGV 253
            +GPPGP      G PG  G PGQPG KGDRG  G  G  G+ GP+G  G  G PGA G 
Sbjct: 475 YRGPPGPQ-----GPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGE 529

Query: 254 -------------KGPPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQG 299
                        KG PG  G PG  G  G  G+ G  G PGP+G  G  G  GE GP G
Sbjct: 530 PGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPG 589

Query: 300 PIGVPGVQ---GPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPG----------LPGPPG 346
            +G PG +   GPPG PG G  G  G  GQ GFPGG G  GLPG          LPGPPG
Sbjct: 590 GVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPG 649

Query: 347 LPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIG--GPPGEPGLPGIPGPMGP 403
             G+ G PGFPGP+GDRG  G PG  G  GEKG +G PGIG  GPPG  G+ G+PG MGP
Sbjct: 650 AEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGP 709

Query: 404 PGAIGFPGPKGEGGIVGPQGP--------PGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP 455
           PG  G PG  G  G  G QG         PG KG PGL G PG PG  G +G PG+ G  
Sbjct: 710 PGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEH 769

Query: 456 GPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIP 515
           G IGP G  G +G PG PG+PG +G  G PGI          G PG  GP G  GPPG+ 
Sbjct: 770 GAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI----------GPPGARGPPGGQGPPGLS 819

Query: 516 GPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV-- 573
           GP G  G  G PGFPG+  PG  G  G  G PG  G  G PGLPG  G PG PG P    
Sbjct: 820 GPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKG 879

Query: 574 ---MPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP 611
              +  TP   G   P    G+ G K  H +    G  G P
Sbjct: 880 EMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDP 920



 Score =  417 bits (1071), Expect = e-116
 Identities = 276/656 (42%), Positives = 314/656 (47%), Gaps = 148/656 (22%)

Query: 118 GEQGPRGE------------PGPRGPPGPPGLPGH-------GIPGIK---GKPGPQGYP 155
           G +G +GE            PG +GP GP G PG        G+PG K   G PG  GYP
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102

Query: 156 G-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI------- 207
           G  G PG+PG  G PG  G+PG  G  G++G +GP G+PG  G PGP GLPG+       
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI 162

Query: 208 ----------------------GKPGGPGLPGQPGPKGDRGPKGLPGPQG---------- 235
                                 G PG PGL G  GP G  GP G PGP G          
Sbjct: 163 LGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGL 222

Query: 236 -LRGPKGDKG----FGMPGAPG-----------VKGPPGMHGPPGPVGLPGVGKPGVTGF 279
             +GPKGDKG     G PG PG            KG  G  G PG  G+PGVG+ G  G 
Sbjct: 223 SFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGK 282

Query: 280 PGPQGPLGK---------PGAPGEP------GPQGPIGVPGVQGPPGIPGI-------GK 317
           PGP+G  GK         PG PGEP      G QGP G  G  GPPG PGI       G+
Sbjct: 283 PGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGE 342

Query: 318 PGQDGIPGQP---GFPGGKGEQGLPGLPGPPGLP---GIGKPGFPGPKGDRGMGGVPGAL 371
            G+ G PG P   G PG KG  GLPG PGPPGLP     G PGFPG +G++G  G PG  
Sbjct: 343 KGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTS 402

Query: 372 --GPRGEKGPIGAPGIGGPPGEPGL--------PGIPGPMGPPGAIGFPGPKGEGG---- 417
             GP G  G  G PG  GPPG+PG         PG PG  GPPG  G PG  GE G    
Sbjct: 403 LPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQ 462

Query: 418 ---------IVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG 468
                    I G +GPPGP+G PG  GFPG+PG  G+ G PG  G+ G  GP+G  G  G
Sbjct: 463 KGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIG 522

Query: 469 VPGLPGVPG-------LLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP 521
            PG  G PG       L G KG+PG PG  G+ G  G PG  G  G  GP G PG  G  
Sbjct: 523 QPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLK 582

Query: 522 GLPGPPGFPGIGKPGVAGLHGPPGKP-----GALGPQGQPGLPGPPGPPGPPGP---PAV 573
           G  GPPG  G+G PG  G  GPPG P     G +G +GQ G PG PG PG PGP   P  
Sbjct: 583 GERGPPG--GVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGK 640

Query: 574 MPPTP-PPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPP 628
           + P P PP  E LP    G  G +    +    G+ G P  +       +  P PP
Sbjct: 641 IVPLPGPPGAEGLPG-SPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPP 695



 Score =  414 bits (1063), Expect = e-115
 Identities = 265/591 (44%), Positives = 308/591 (52%), Gaps = 101/591 (17%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-------GIPGIKGKPGPQGYPG------VGKPGMPG 164
            G  G  G PGP+G PG  GL G        G PG +G  GP G PG      +G  G  G
Sbjct: 562  GRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAG 621

Query: 165  MPGKPGAMGMPGAKGEIGQ----KGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQ- 218
             PG PG+ G+PG KGE G+     G  G  G+PG  G PGP G  G  G PG PGLPG+ 
Sbjct: 622  FPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEK 681

Query: 219  ----------PGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGV---KGPPGMHGPPG 264
                      PGP G +G  GLPG  G  G  G  GF G+PG PGV   KG PG+ G PG
Sbjct: 682  GAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV-GLPG 740

Query: 265  PVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQG---PPGIPG-IGKPGQ 320
              GLPG+  PG+ G PG +G +G PG PGE G  GP G+ G++G   PPG+PG +G PG 
Sbjct: 741  LKGLPGL--PGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGV 798

Query: 321  DGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPG-----PKGDRGMGGVPGALGPR 374
             GI G PG  G  G QG PGL GPPG+ G  G PGFPG     PKGD+G  G+PG  G  
Sbjct: 799  PGI-GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQS 857

Query: 375  GEKG---PIGAPGIGGPPGE---------PGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQ 422
            G  G     GAPGI G PG          PG PG PGP+G PG  G  G  G  G  GP+
Sbjct: 858  GLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPR 917

Query: 423  GPPGPKGEPGLQGFPGKPGFL---------GEVGPPGMRGLPGPIGPKGEAGQKGVPGLP 473
            G PG KG+ G  G PGKPG +         G+ G  G +G  GPIG KG  G  G PG+P
Sbjct: 918  GDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVP 977

Query: 474  GVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPI------------GPPGIPGPKGEP 521
            G  G  G  G+PG  GD G+ G PG PG+ GP G +            G PGIPGP+G P
Sbjct: 978  GKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSP 1037

Query: 522  GLPGPPGF---------PGIGKPGV------AGLHGPPGKPGALGPQGQPGLPGPPGPPG 566
            GLPG  G          PGIG PG+       G+ G PG PG  G +G  G+PG PG PG
Sbjct: 1038 GLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPG 1097

Query: 567  PPGPPAVM--PPTPPPQGEYLPDMGL-GIDGVKPPHAYGAKKGKNG--GPA 612
              G P  +  P +P   GE   D GL G+DG+          G  G  GPA
Sbjct: 1098 LKGSPGSVGYPGSPGLPGE-KGDKGLPGLDGIPGVKGEAGLPGTPGPTGPA 1147



 Score =  409 bits (1051), Expect = e-114
 Identities = 304/781 (38%), Positives = 352/781 (45%), Gaps = 206/781 (26%)

Query: 32  GIKPLPPQIPPQMPPQIPQYQPL-GQQVPHMPLAKDGLAMGKEMPHLQYGKEYP-----H 85
           G+  +P Q  P  PP IP      G++ P  P    G A     P L   K  P     H
Sbjct: 106 GLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGH 165

Query: 86  LPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH----- 140
           +P  + + +     G   +P       L  L+G  GP G  GP GPPGPPG PG      
Sbjct: 166 VPGMLLKGE----RGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMG 221

Query: 141 ----GIPGIKGKPGPQGYPGV---------------------GKPGMPGMPG-----KPG 170
               G  G KG  G  G PGV                     G+PG  GMPG     +PG
Sbjct: 222 LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPG 281

Query: 171 AMGMPGAKGEIGQKGEIGPMGIPGPQGPP---------------GPHGLPGI-------G 208
             G  G  G+ G KGE G  G PG  G P               GP G PGI       G
Sbjct: 282 KPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLG 341

Query: 209 KPGGPGLPGQPGPKGDRGPKGL------PGPQGL--------------RGPKGDKGF--- 245
           + G  G PG PGP+G+ GPKG       PGP GL              RG KGD+GF   
Sbjct: 342 EKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGT 401

Query: 246 ---------GMPGAPGVKGPPG-----------MHGPPGPVGLPGV-GKPGVTGF----- 279
                    G+PG PG  GPPG             GPPG  G PG+ G+PG  G      
Sbjct: 402 SLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKG 461

Query: 280 -----------------PGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-------I 315
                            PGPQGP G+ G PG+PG +G  G+PG  G  G+PG       I
Sbjct: 462 QKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLI 521

Query: 316 GKPGQDGIPGQ-------------PGFP---------GGKGEQGLPGLPGPPGLPGI--- 350
           G+PG  G PG+             PGFP         G  G  G PGLPGP G PG    
Sbjct: 522 GQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGL 581

Query: 351 -------GKPGFPGPKGDRGMGGVP--GALGPRGEKGPI------GAPGIGGPPGEPG-- 393
                  G  GFPG +GD G  G P  G  GP G+KG        G+PG+ GP GEPG  
Sbjct: 582 KGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKI 641

Query: 394 --LPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGM 451
             LPG PG  G PG+ GFPGP+G+ G  G  G PG  GE G  G PG  GF G  GP G+
Sbjct: 642 VPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG-IGFPGPPGPKGV 700

Query: 452 RGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGI--PGDQGLQGPPGIPGIGGPSGPI 509
            GLPG +GP G  G+ G  GLPG PG+ G KGEPG+  PG +GL G PGIPG  G  G I
Sbjct: 701 DGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSI 760

Query: 510 GPPGIPGPK---GEPGL------PGPPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLP 559
           G PG+PG     G PGL      PGPPG PG +G PGV G+ GPPG  G  G QG PGL 
Sbjct: 761 GVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLS 819

Query: 560 GPPGPPGPPGPPAVMP-PTPPPQGEYLPDMGL-GIDGVKPPHAYGAKKGKNGGPAYEMPA 617
           GPPG  G  G P       P P+G    D G  G+ G+          G+ G P   +P 
Sbjct: 820 GPPGIKGEKGFPGFPGLDMPGPKG----DKGAQGLPGITGQSGLPGLPGQQGAPG--IPG 873

Query: 618 F 618
           F
Sbjct: 874 F 874



 Score =  362 bits (928), Expect = e-100
 Identities = 241/575 (41%), Positives = 280/575 (48%), Gaps = 93/575 (16%)

Query: 144 GIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGP---P 199
           G+KG+ G +G PG+ G  G PGM G  G  G PG KG+ G+ G  G  G  GP G    P
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102

Query: 200 GPHGLPGI----GKPGGPGLPGQPGPKGDRGP---------KGLPGPQGLRGPKGDKGFG 246
           G  GLPGI    G PG PG+PG  G KG+RGP          G PGP GL G KGD G  
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI 162

Query: 247 MPGAPGV-----KGPPGMHGPPGPVGLPG----VGKPGVTGFPGPQGPLGKPGAPGE--- 294
           +   PG+     +G PG+ G PGP GLPG    VG PG TG PGP GP G PG  G+   
Sbjct: 163 LGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGL 222

Query: 295 --PGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGK 352
              GP+G  G  GV GPPG+PG  +  + G        G KG++G PG  G PG+   G+
Sbjct: 223 SFQGPKGDKGDQGVSGPPGVPGQAQVQEKG---DFATKGEKGQKGEPGFQGMPGVGEKGE 279

Query: 353 PGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGP 412
           PG PGP+G  G  G  G  G  G  G  G PG+ G  G  G  G  GP GPPG +   GP
Sbjct: 280 PGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGP 339

Query: 413 KGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVG--PPGMRGLPGPIGPKGEAGQKGVP 470
            GE G  G  G PGP+GEPG +GFPG PG  G  G   PG  G PG  G +GE G +G P
Sbjct: 340 LGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFP 399

Query: 471 -----------GLPGVPGLLGPKGEPGI--------PGDQGLQGPPGIPGIGGPSGPI-- 509
                      GLPG PG  GP G+PG         PG  G QGPPGIPG  G  G I  
Sbjct: 400 GTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGE 459

Query: 510 -----------------GPPGIPGPKGEPGLPGPPGFPG----IGKPGVAGLHGPPGKPG 548
                            GPPG  GP GE G PG PG  G     G+ GVAG+ GP G PG
Sbjct: 460 KGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPG 519

Query: 549 AL---GPQGQPG-------LPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPP 598
            +   G +G+PG       L G  G PG PG P +      P  +  P    G+ G K  
Sbjct: 520 LIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHP----GLPGPKGS 575

Query: 599 HAYGAKKGKNGGP-AYEMPAFTAELTAPFPPVGAP 632
                 KG+ G P     P    +   P PP   P
Sbjct: 576 PGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGP 610



 Score =  214 bits (544), Expect = 3e-55
 Identities = 151/386 (39%), Positives = 171/386 (44%), Gaps = 103/386 (26%)

Query: 349 GIGKPGFPGPKGDRGMGGVPGAL------GPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 402
           G GK    G KG +G  G+PG        G +G +GP G PG  G  GEPGLPG  G  G
Sbjct: 35  GCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRG 94

Query: 403 PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGF---------PGKPGFLGEVGP---PG 450
           PPGA G+PG  G  GI G  GPPGP G PG  G          PG PGF G  GP   PG
Sbjct: 95  PPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPG 154

Query: 451 MRGLPGPI----------GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIP 500
           M+G PG I          G +G  G  G PG PG+PGL GP G PG  G  G  GPPG P
Sbjct: 155 MKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214

Query: 501 G----IG----------GPSGPIGPPGIP-----------------GPKGEPGLPGPPGF 529
           G    +G          G  G  GPPG+P                 G KGEPG  G PG 
Sbjct: 215 GEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGV 274

Query: 530 PGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP---------------GPPGPPAVM 574
              G+PG  G  G PGK G  G +G PG PG PG P               GPPGPP ++
Sbjct: 275 GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334

Query: 575 --------------PPTPPPQGEYLPD--MGL----GIDGVKPPHAYGA--------KKG 606
                         P TP P+GE  P    GL    G  G+  P   GA        +KG
Sbjct: 335 IGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKG 394

Query: 607 KNGGPAYEMPAFTAELTAPFPPVGAP 632
             G P   +P  +     P PP G+P
Sbjct: 395 DRGFPGTSLPGPSGRDGLPGPP-GSP 419



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 56/153 (36%), Positives = 65/153 (42%), Gaps = 24/153 (15%)

Query: 503 GGPSGPIGPPGIPGPKGE---PGLPGPPGFPGI----------------GKPGVAGLHGP 543
           G   G     G+ G KGE   PGL G  GFPG+                G+PG+ G  G 
Sbjct: 33  GSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGT 92

Query: 544 PGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLP--DMGL-GIDGVKPPHA 600
            G PGA G  G PGLPG PG  GPPGPP + P     +GE  P    GL G  G   P  
Sbjct: 93  RGPPGASGYPGNPGLPGIPGQDGPPGPPGI-PGCNGTKGERGPLGPPGLPGFAGNPGPPG 151

Query: 601 YGAKKGKNGGPAYEMPAFTAELTAPFPPV-GAP 632
               KG  G     +P    +    FP + G P
Sbjct: 152 LPGMKGDPGEILGHVPGMLLKGERGFPGIPGTP 184


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  447 bits (1150), Expect = e-125
 Identities = 275/622 (44%), Positives = 315/622 (50%), Gaps = 135/622 (21%)

Query: 118  GEQGPRGEPGPRGPPGPPG---LPGH----GIPGIKGKPGPQGYPGV------------- 157
            G QGP G PGP+GPPGPPG   LPGH    G  G +GK GP G PGV             
Sbjct: 952  GPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPM 1011

Query: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG----------I 207
            G+ G PG PG PG  G+PG  G+ G KG+ GP G+PG  GPPG  G PG          +
Sbjct: 1012 GERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGAL 1071

Query: 208  GKPGGPGLPGQPGPKG---DRGPKGL---------PGPQGLRGPKGDKGF-------GMP 248
            G  G  G PG PGP G   +RGP G          PGPQG  GP G+KG        G  
Sbjct: 1072 GLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1131

Query: 249  GAPGVKGPPGMHGPPGPVGLPG-------VGKPGVTGFPG------------PQGPLGKP 289
            G  G++GP G+ GP GPVG PG       +G+PG  G  G            PQGP+G+P
Sbjct: 1132 GRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQP 1191

Query: 290  G---APGEPGP------------QGPIGVPGVQGPPGIPGI-GKPGQDGIPGQ------P 327
            G   A GEPGP            +GP G PG  GP G+ G+ G PG+ G  G       P
Sbjct: 1192 GPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPP 1251

Query: 328  GFPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGM---------GGVPGALGPRGEK 377
            G PG +G  G PG  GP G PG IG PG  G KG+ G          GG PG  G RGEK
Sbjct: 1252 GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEK 1311

Query: 378  GPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPG---PKGEGGIVGPQGPPGPKG---EP 431
            G  G  G  GPPG  G PG  GP G PG +GFPG   P GE G  G  GPPG KG   EP
Sbjct: 1312 GESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEP 1371

Query: 432  GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQK------GVPGLPGVPGLLGPKGEP 485
            G  G PG  G  G  GPPG RG PGP GP+G  G+K      G+ G PG  G +GP+G P
Sbjct: 1372 GQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAP 1431

Query: 486  GIPGDQGL---------QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI---- 532
            G PG  GL         QG PG PG  GP GP+GPPG+PG KG+ G  G  G PG+    
Sbjct: 1432 GKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLI 1491

Query: 533  ---GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMG 589
               G+ G  G  G PG  G+ GP+G+ G+ GP GP GPPGPP  +P  P P+G       
Sbjct: 1492 GPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG-LPGPPGPKG------A 1544

Query: 590  LGIDGVKPPHAYGAKKGKNGGP 611
             G  G   P       G  G P
Sbjct: 1545 KGSSGPTGPKGEAGHPGPPGPP 1566



 Score =  439 bits (1130), Expect = e-123
 Identities = 286/639 (44%), Positives = 323/639 (50%), Gaps = 81/639 (12%)

Query: 53   PLGQQVPHMPLAKDGLA--MGKEMPHLQYGK-EYPHLPQYMKEIQPAPRMGKEAVP---- 105
            P G+  P  P  + G     G   P  + GK   P LP Y     P   +G    P    
Sbjct: 836  PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG 895

Query: 106  -KKGKEIP----LASLRGEQGPRGEPGPRGPPGPPGLPGH-------GIPGIKGKPGPQG 153
             K G+  P        RG  GPRGE GPRG  G PG  G+       G PG +G  GPQG
Sbjct: 896  EKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQG 955

Query: 154  YPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG---PQGP----------- 198
              G  G  G PG PGK G  G PG +GE G +G+ GP G PG   PQGP           
Sbjct: 956  PTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG 1015

Query: 199  -PGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPG---PQGLRGPKGDKGFGMP-GAPGV 253
             PGP G PG  + G PGL G+ G KGD GP GLPG   P GLRG  GD+G   P GA G+
Sbjct: 1016 HPGPPGPPG--EQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073

Query: 254  KGPPGMHGPPGPVGLPG----------VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGV 303
            KG  G  GPPGP G PG          +G PG  G  GP GP G+ GAPGE GPQGP G 
Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133

Query: 304  PGVQGPPGIPG----IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG----IGKPGF 355
             G+QGP G+PG    +G PG+DG  G+ G PG KG +G  G  GPPG  G    IG+PG 
Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193

Query: 356  PGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE 415
             G  G+ G  G  G  G +G++GP G PG   PPG  GL G+PGP         PG KGE
Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPG---PPGPVGLQGLPGP---------PGEKGE 1241

Query: 416  GGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV 475
             G VG  GPPGP   PG +G  G PG  G  GPPG  G PG +G KGE G+ G PGLPG 
Sbjct: 1242 TGDVGQMGPPGP---PGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298

Query: 476  PGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKP 535
             G  GPKGE G  G+ G  G  G PG  GP G  GP G PGP G PG PGPP     G+P
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPP-----GEP 1353

Query: 536  GVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP--PQGEYLPDMGLGID 593
            G AG  GPPG  G  G  GQ G PGP G PGP GPP    P  P  P+G        G  
Sbjct: 1354 GPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEA 1413

Query: 594  GVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
            G++ P       G  G P    P     +  P    G P
Sbjct: 1414 GLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLP 1452



 Score =  423 bits (1088), Expect = e-118
 Identities = 269/617 (43%), Positives = 307/617 (49%), Gaps = 70/617 (11%)

Query: 80   GKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG 139
            G + P +     + Q   +  + A+      + L    G  GP G  G +G PG  G   
Sbjct: 533  GSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVG--P 590

Query: 140  HGIPGIKGKPGPQGYPG----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP 195
             G  G++G PGP G PG     G  G  GMPG+ G  G  G  G  G  GE G  G PGP
Sbjct: 591  QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650

Query: 196  QGPPGPHGLPG----IGKPGGPGLPGQPGPKGDRGPKGLPGP---------QGLRGPKGD 242
             GPPGP G  G     G+ G  GLPG+PGP+G  GPKG PGP          G  GPKG+
Sbjct: 651  SGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGN 710

Query: 243  KG-FGMPGAPGVKGPPGMHGPPGP---VGLPG----VGKPGVTGFPGPQGPLGKPGAPGE 294
             G  G PG PG +G PG  G PGP   +G PG    +GKPG+ G PG  GP G PG  G 
Sbjct: 711  VGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGP 770

Query: 295  PGPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG-IGK 352
            PG +G  G PG QGP G PG  G  G DGI G  G  G KGE G PG  G  G+ G  G+
Sbjct: 771  PGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGE 830

Query: 353  PGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP-- 410
             G PGP+G+ G  G  G  GP G+ GP+G PG  G  G PGLPG PG  GP G+IGFP  
Sbjct: 831  IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGF 890

Query: 411  ----------GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE------VGPPGMRGL 454
                      G  G+ G  G +GP GP+GE G +G  GKPG  G        GPPG RG 
Sbjct: 891  PGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950

Query: 455  PGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGI 514
             GP GP G  G KG PG PG  GL G  G+ G  G QG  GPPG PG+ GP GP G  G 
Sbjct: 951  NGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP 1010

Query: 515  PGPKGEPGLPGPPGFPGI----------GKPGVAGLHGPPGKPGALGPQGQPGLPGP--- 561
             G +G PG PGPPG  G+          G PG AGL G  G PG  G  G  GLPGP   
Sbjct: 1011 MGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGA 1070

Query: 562  ------PGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEM 615
                   GPPGPPG PA  P    P G   P   +GI G   P       G+ G P  + 
Sbjct: 1071 LGLKGNEGPPGPPG-PAGSPGERGPAGAAGP---IGIPGRPGPQGPPGPAGEKGAPGEKG 1126

Query: 616  PAFTAELTAPFPPVGAP 632
            P   A       PVG P
Sbjct: 1127 PQGPAGRDGLQGPVGLP 1143



 Score =  419 bits (1076), Expect = e-117
 Identities = 279/674 (41%), Positives = 317/674 (47%), Gaps = 113/674 (16%)

Query: 49   PQYQPLGQQV---PHMPLAKDGLAMGKEMPHLQYG-KEYPHL--PQYMKEIQPAPRMGKE 102
            P Y P        P MP  +D +  G   P  + G K  P +  P  + E  P P  G  
Sbjct: 419  PYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPE-GPA 477

Query: 103  AVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKP----------GP 151
             +P            G  G  G+PG RGPPG PGLPG  G+PG  G            G 
Sbjct: 478  GLPGP------PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGD 531

Query: 152  QGYPGV---------------------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPM 190
             G  G                      G  G  G+ G+PG +G PG+ G  G+ G++GP 
Sbjct: 532  AGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQ 591

Query: 191  GIPGPQGPPGPHGLPG----IGKPGGPGLPGQPGPKGDRGPKGL------------PGPQ 234
            G  G QGPPGP G PG     G  G  G+PGQ GPKGDRG  GL            PGP 
Sbjct: 592  GPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPS 651

Query: 235  GLRGPKGDKGF----------GMPGAPGVKGPPGMHGPPGPVGLPGV----------GKP 274
            G  GP GD G           G+PG PG +G  G  GPPGP G PGV          G  
Sbjct: 652  GPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNV 711

Query: 275  GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGK 333
            G  G PGP G  G PGA G PGPQG IG PG +GP G PG+ G PG DG PG PG  G  
Sbjct: 712  GPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPP 771

Query: 334  GEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG 393
            GE+G  G PGP G       G+PGP+G +G  G+ G  G +GEKG  G PG  G  G  G
Sbjct: 772  GEKGGQGPPGPQG-----PIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKG 826

Query: 394  LPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRG 453
              G  GP GP G  G  GPKG GG  G  GP GP GE G  G PG PG+ G  GP G  G
Sbjct: 827  DRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIG 886

Query: 454  LPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPP- 512
             PG  G  GE G +G PG PG  G  GP G  G  G +G+ G PG  G  G  GP GPP 
Sbjct: 887  FPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPG 946

Query: 513  -----------GIPGPKGEPGLPGPPGFPG----IGKPGVAGLHGPPGKPGALGPQGQPG 557
                       G PGPKG PG PG  G PG     G+ G  G  GPPG PG +GPQG  G
Sbjct: 947  ERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTG 1006

Query: 558  LPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPA 617
              GP G  G PGPP       PP  + LP +  G +G K         GK+G P   +  
Sbjct: 1007 ETGPMGERGHPGPPG------PPGEQGLPGLA-GKEGTKGDPGPAGLPGKDGPPG--LRG 1057

Query: 618  FTAELTAPFPPVGA 631
            F  +   P  PVGA
Sbjct: 1058 FPGDRGLP-GPVGA 1070



 Score =  397 bits (1020), Expect = e-110
 Identities = 244/528 (46%), Positives = 273/528 (51%), Gaps = 91/528 (17%)

Query: 95   PAPRMGKEAVP-------KKGKEIPLASL--RGEQGPRGEPGPRGPPGPPGLPGHGIP-G 144
            PA   GK+  P        +G   P+ +L  +G +GP G PGP G PG  G  G   P G
Sbjct: 1043 PAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG 1102

Query: 145  IKGKPGPQGYPG-VGKPGMPG------------------MPGKPGAMGMPGA---KGEIG 182
            I G+PGPQG PG  G+ G PG                  +PG  G +G PG    KGEIG
Sbjct: 1103 IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIG 1162

Query: 183  QKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGLPGQPGP---------KGDRGPKGLPG 232
            + G+ G  G  G QGPPGP G  G IG+PG  G  G+PGP         KGD GP+G PG
Sbjct: 1163 EPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPG 1222

Query: 233  P------QGLRGPKGDKG-------FGMPGAPGVKGPPGMHGPPGPVGLPG-VGKPGVTG 278
            P      QGL GP G+KG        G PG PG +GP G  G  GP G PG +G PG  G
Sbjct: 1223 PPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVG 1282

Query: 279  FPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQG 337
              G  G  G+PG PGE GP GP G  G +G  G  G  G PG  G PG  G  G  G  G
Sbjct: 1283 EKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVG 1342

Query: 338  LPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG 396
             PG PGPPG PG  G+ G PG KGD G  G  G+ GP GE GP G PG  GPPG  G  G
Sbjct: 1343 FPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEG 1402

Query: 397  IPGPMGPPGAIGFPGPKGEGGIVGPQGPPG------------PKGEPGLQGFPGKPGFLG 444
              G  G  G  G  GP G+ G +GPQG PG            P GE GL G PG  G  G
Sbjct: 1403 RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPG 1462

Query: 445  EVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG 504
             +GPPG+ GL G  GPKGE G  G+ GL G PG  G KG+ G+PG QG  GP G  GI G
Sbjct: 1463 PMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG 1522

Query: 505  PSGPIGPPGIPG------------------PKGE---PGLPGPPGFPG 531
            PSGPIGPPG PG                  PKGE   PG PGPPG PG
Sbjct: 1523 PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  311 bits (796), Expect = 2e-84
 Identities = 203/493 (41%), Positives = 239/493 (48%), Gaps = 93/493 (18%)

Query: 36   LPPQIPPQMPP-QIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQ 94
            +P +  PQ PP    +    G++ P  P  +DGL     +P    G   P  P       
Sbjct: 1103 IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLP----GPAGPVGP------- 1151

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154
            P     K  + + G++      +G++G +G PGP GP GP G PG    G  G+PGP+G 
Sbjct: 1152 PGEDGDKGEIGEPGQK----GSKGDKGEQGPPGPTGPQGPIGQPGPS--GADGEPGPRGQ 1205

Query: 155  PGV-------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI 207
             G+       G  G PG PG  G  G+PG  GE G+ G++G MG PGP GP GP G PG 
Sbjct: 1206 QGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGA 1265

Query: 208  ----GKPGG------------------PGLPGQ---PGPKGDRGPKGLPGPQGLRGPKGD 242
                G PGG                  PGLPG+   PGPKG+RG KG  GP G  GP G 
Sbjct: 1266 DGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGP 1325

Query: 243  KGF----------------GMPGAPGVKGPPGMHGPPGPVGLPG----VGKPGVTGFPGP 282
            KG                 G PG PG  GP G  GPPG  G  G     G PG TG PGP
Sbjct: 1326 KGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGP 1385

Query: 283  QGPLGKPGAPGEPGPQG------PIGVPGVQGPPGIPGI----GKPGQDGIPGQPGFPGG 332
             GP GK G PG  GP+G        G  G++GPPG  G     G PG+ G  G  G PG 
Sbjct: 1386 SGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGP 1445

Query: 333  KGEQGLPGLPGPPGLPG-IGKPGFPG------PKGDRGMGGVPGALGPRGEKGPIGAPGI 385
             GEQGLPG PGP G PG +G PG PG      PKG++G  G+ G +GP GE+G  G  G+
Sbjct: 1446 VGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGL 1505

Query: 386  GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445
             GP G  G  G  G  GP G IG PGP       G  GPPGPKG  G  G  G  G  G 
Sbjct: 1506 PGPQGSSGPKGEQGITGPSGPIGPPGPP------GLPGPPGPKGAKGSSGPTGPKGEAGH 1559

Query: 446  VGPPGMRGLPGPI 458
             GPPG  G PG +
Sbjct: 1560 PGPPGPPGPPGEV 1572



 Score =  137 bits (345), Expect = 4e-32
 Identities = 83/198 (41%), Positives = 94/198 (47%), Gaps = 49/198 (24%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPG----VGKPGMPGMPGKPGAM 172
            GE GP G PG RGPPGP G  G  G  G KG+ G +G PG    +G  G PG PG  G  
Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440

Query: 173  GMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-------GKPGGPGLPGQPGPKGDR 225
            G+PG  GE G  G  GP G PGP GPPG  GL G        G PG  GL G PG +G++
Sbjct: 1441 GIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500

Query: 226  GPKGLPGPQGLRGPKGDKGF-------------------------------------GMP 248
            G +GLPGPQG  GPKG++G                                      G P
Sbjct: 1501 GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHP 1560

Query: 249  GAPGVKGPPGMHGPPGPV 266
            G PG  GPPG    P P+
Sbjct: 1561 GPPGPPGPPGEVIQPLPI 1578


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  441 bits (1135), Expect = e-124
 Identities = 293/705 (41%), Positives = 344/705 (48%), Gaps = 123/705 (17%)

Query: 47   QIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKE----YPHLPQYMKEIQPAPRMGKE 102
            ++ Q  P G+  P  P  + G   G   P  Q G++     P LP Y     P    G  
Sbjct: 812  EVGQIGPRGEDGPEGPKGRAG-PTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870

Query: 103  AVPKKGKEIPLASLRGEQGPRGEPGPRGP------------PGPPGLPGH----GIPGIK 146
              P    E     + G+ GPRG+ GP GP            PGP G  G     G PG +
Sbjct: 871  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930

Query: 147  GKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLP 205
            G  GPQG  G  G  G PG PGK G  G PG +GE G +G+ GP G  G  GP GP G  
Sbjct: 931  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 990

Query: 206  G-IGKPGGPGLPGQPGP------------KGDRGPKGLPG---PQGLRGPKGDKGF-GMP 248
            G IG+ G PG PG PG             KGD GP+G+ G   P GLRG  G++G  G  
Sbjct: 991  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1050

Query: 249  GAPGVKGPPGMHGPPGPVGLPG----------VGKPGVTGFPGPQGPLGKPGAPGEPGPQ 298
            GAPG+KG  G  GPPGPVG PG          +G PG  G  GP GP G+ GAPGE GPQ
Sbjct: 1051 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1110

Query: 299  GPIGVPGVQGPPGIPG----IGKPGQDGIPGQ---PGFPGGKGEQGLPGLPGPPGLPG-I 350
            GP G  GVQGP G+PG     G PG+DG  G+   PG  G KG++G  G PGPPGL G +
Sbjct: 1111 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1170

Query: 351  GKPG---------------------------FPGPKGDRGMGGVPGALGPRGEKG---PI 380
            G PG                           FPGP G  G+ G+PG  G +GE G   P+
Sbjct: 1171 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1230

Query: 381  GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP 440
            G PG  GP G  G  G  GP GPPG++G  G  GE G  G  G PGP GE G+ G  G+ 
Sbjct: 1231 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1290

Query: 441  GFLGE------VGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQ 494
            G  GE       GPPG +G PG  GPKG  G  G PG PG PG  GP G+ G+ GD+G  
Sbjct: 1291 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1350

Query: 495  GPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQ 553
            G PG PG  GPSG  GPPG PG +G PG  G  G  G  G  G AG  GPPGK G +GPQ
Sbjct: 1351 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1410

Query: 554  GQPGLPGP---------------------PGPPGPPGPPAV--MPPTPPPQGEYLPDMGL 590
            G  G PGP                      GPPGP GPP +  +   P  +GE      +
Sbjct: 1411 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1470

Query: 591  GIDGVKPPHAYGAKKGKNGGPAYE-MPAFTAE--LTAPFPPVGAP 632
            G+ G  PP   G +KG  G P  +  P    +  +  P  P+G P
Sbjct: 1471 GLIG--PPGEQG-EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1512



 Score =  434 bits (1115), Expect = e-121
 Identities = 284/642 (44%), Positives = 322/642 (50%), Gaps = 105/642 (16%)

Query: 37   PPQIPPQMPPQIPQYQPLG---QQVPHMPLAKDGLA-----------MGKEMPHLQYGKE 82
            PP  P +  PQ PQ  P+G    + P  P  KDGL             GK  P    G  
Sbjct: 923  PPGPPGERGPQGPQ-GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVV 981

Query: 83   YPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGP------------RG 130
             P  P    E  P    G    P    E  L    G++G +G+PGP            RG
Sbjct: 982  GPQGPT--GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1039

Query: 131  PPGPPGLPG-HGIPGIKGKPGPQGYPG-VGKPGMPG---------MPGKPGAMGMPGAKG 179
             PG  GLPG  G PG+KG  GPQG PG VG PG  G         +PG+PG  G PG  G
Sbjct: 1040 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1099

Query: 180  EIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP----------GLPGQPGPKGDRGPKG 229
            E G  GE GP G  G  G  GP GLPG   P G           G PGQ G KGD+G  G
Sbjct: 1100 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159

Query: 230  LPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHG------------PPGPVGLPGV-GKPG 275
             PGP GL+GP G  G  G  G PG +G  GM G            PPGP+GL G+ G PG
Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219

Query: 276  VTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG----IPGIGKPGQDGIPGQPGFPG 331
              G  G  GP+G PG PG  GPQGP G  G QGPPG    + G+G+ G+ G  G PG PG
Sbjct: 1220 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1279

Query: 332  G------------KGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGP 379
                         KGE G PG  GPPG  G   PG  GPKG+ G  G PG  GP GE GP
Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKG--PPGDDGPKGNPGPVGFPGDPGPPGEPGP 1337

Query: 380  IGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE------GGIVGPQGPPGPKGEPGL 433
             G  G+GG  GE G PG PGP GP G  G PGP G+       G  G QG  G KGE G 
Sbjct: 1338 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1397

Query: 434  QGFPGKPGFLG------EVGPPGMRGLPGPIGPKG---EAGQKGVPGLPGVPGLLGPKGE 484
            +G PGK G +G      + GP G+RG+PGP+G +G    AGQ G PG  G PGL G KG+
Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1457

Query: 485  PGIPGDQG------LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGV 537
            PG  G++G      L GPPG  G  G  G  G  G PG KG+ G+PGP G  G  G PG+
Sbjct: 1458 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1517

Query: 538  AGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPA-VMPPTP 578
             G  GP G  G+ GP GQ G  G PGPPG PGPP  V+ P P
Sbjct: 1518 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559



 Score =  419 bits (1078), Expect = e-117
 Identities = 264/611 (43%), Positives = 307/611 (50%), Gaps = 103/611 (16%)

Query: 92   EIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGP 151
            E  P   +G    P    +  +A + G  GP+G  GP+G PGPPG  G+  PG +G PGP
Sbjct: 659  EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN--PGPQGLPGP 716

Query: 152  QGYPG-------VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGL 204
            QG  G        GKPG+ G+PG  G  G PG +G+ G+KG +GP G  GP G PGP G+
Sbjct: 717  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 776

Query: 205  PGI-------------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP--- 248
             G              G+ G PG  G  G KGDRG  G  GP+G  GP+G KG   P   
Sbjct: 777  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 836

Query: 249  -------------GAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEP 295
                         G PG+ G PG  GP G  G PG   PG  G  G +G  GKPG  G+ 
Sbjct: 837  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF--PGANGEKGARGVAGKPGPRGQR 894

Query: 296  GPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG----I 350
            GP GP G  G +GP G PG  G  G DG PG PG  G +G QG  G PGP G PG     
Sbjct: 895  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954

Query: 351  GKPGFPGPKGDRGM---------GGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM 401
            G PG PG +G+ G          GGV G  GP GE GPIG  G  GPPG PG  G+PG  
Sbjct: 955  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014

Query: 402  GPPGAIGFPGPKGEGGIVGP---QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI 458
            G  GA G PGP+G  G  GP   +G PG +G PG QG PG  G  G  GPPG  G PG  
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074

Query: 459  GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGP---SGPIGPPGIP 515
            G  G AG  G+PG PG  G  GP GE G PG++G QGP G  G+ GP    GP GP G P
Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1134

Query: 516  ------------------GPKGEPGLPGPPGFPG-IGKPGVAGLHGPP---GKPGALGPQ 553
                              G KGE G PGPPG  G +G PG+AG  G P   G+ G  G +
Sbjct: 1135 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1194

Query: 554  GQPGLPGPPGPPGP------PGPPA----------VMPPTPP-PQGEYLPDMGLGIDGVK 596
            G  G  G PGPPGP      PGPP           + PP PP P+G   P+   G DG +
Sbjct: 1195 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN---GADGPQ 1251

Query: 597  -PPHAYGAKKG 606
             PP + G+  G
Sbjct: 1252 GPPGSVGSVGG 1262



 Score =  418 bits (1074), Expect = e-116
 Identities = 268/637 (42%), Positives = 298/637 (46%), Gaps = 114/637 (17%)

Query: 97   PRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQG--- 153
            P M  E  P       +    G QGP G PG  G  GPPG P  G+PG  G PGP G   
Sbjct: 448  PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP--GLPGADGLPGPPGTML 505

Query: 154  -----YPGVGK--------------------------PGMPGMPGKPGAMGMPGAKGEIG 182
                 Y G G                           PG  G+ G+PG +G PG+ G  G
Sbjct: 506  MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 565

Query: 183  QKGEIGPMGIPGPQGPPGPHGLPG----IGKPGGPGLPGQPGPKGDRGPKGLP------- 231
            + G+ GP G  G QGPPGP G PG     G  GG G+PG+PG KGDRG  GLP       
Sbjct: 566  ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKG 625

Query: 232  -----GPQGLRGPKGDKG-------FGMPGAPGVKGPPGMHGPPGPVGLPG-VGKPGVTG 278
                 GPQG  GP GD G        G  G PG  GP G+ GP G  G PG  G  GV G
Sbjct: 626  HRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 685

Query: 279  FPGPQ---GPLGKPGAPGE---------PGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPG 325
             PGP+   GP G+PG PG+         PGPQGPIG PG +GP G PG+ G PG DG PG
Sbjct: 686  PPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 745

Query: 326  QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385
             PG  G  GE+G  G PGP      G  G+PGP+G +G  GV G  G +GEKG  G PG 
Sbjct: 746  HPGKEGQSGEKGALGPPGPQ-----GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF 800

Query: 386  GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445
             G  G  G  G  G +GP G  G  GPKG  G  G  GP G  GE G  G PG PG+ G 
Sbjct: 801  KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGR 860

Query: 446  VGPPGMRGLPGPIGPKGEAGQKGVPGLP------------GVPGLLGPKGEPGIPGDQGL 493
             GP G  G PG  G  GE G +GV G P            G  G  GP G+PG  G  G 
Sbjct: 861  QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGG 920

Query: 494  QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG-------------IGKPGVAGL 540
             GPPG PG  GP GP GP G PGPKG PG PG  G PG              G PG  G+
Sbjct: 921  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 980

Query: 541  HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV-----MPPTPPPQGEYLPDMGLGIDGV 595
             GP G  G  GP G+ G PGPPGPPG  G P           P PQG    D   G+ G 
Sbjct: 981  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 1040

Query: 596  KPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
                     +G  G    E P        P  PVG+P
Sbjct: 1041 PGERGLPGAQGAPGLKGGEGP------QGPPGPVGSP 1071



 Score =  345 bits (885), Expect = 9e-95
 Identities = 229/537 (42%), Positives = 261/537 (48%), Gaps = 76/537 (14%)

Query: 163 PGMPGKPG----AMGMPGAKGEIGQKGEIGPM-------GIPGPQGPPGPHGLPGIGKPG 211
           PG+P +      ++   GA GE GQKGE   +       G PGP GP G  G PG+  P 
Sbjct: 415 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT 474

Query: 212 GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP---GAPGVKGPP----------- 257
           GP  PG PG +G  G  GLPG  GL GP G     +P   G  G KGP            
Sbjct: 475 GP--PGDPGDRGPPGRPGLPGADGLPGPPGTM-LMLPFRYGGDGSKGPTISAQEAQAQAI 531

Query: 258 ------GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311
                  + GPPGP+GL   G+PG  G PG  G  G+ G   +PGPQGP GV G  GP G
Sbjct: 532 LQQARIALRGPPGPMGL--TGRPGPVGGPGSSGAKGESG---DPGPQGPRGVQGPPGPTG 586

Query: 312 IPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGG 366
            PG  G+PG DG  G PG PG KG++G  GLPG PG  G     G  G PGP GD GM G
Sbjct: 587 KPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRG 646

Query: 367 VPGALGPRG---EKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG 423
             G +GPRG   E GP G  G  G PG PG PG+ G  GPPG  G  GP+GE G  G QG
Sbjct: 647 EDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG 706

Query: 424 PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGL------------------------PGPIG 459
            PGP+G PG QG  G PG  G  G PG+ GL                        PGP G
Sbjct: 707 NPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQG 766

Query: 460 PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKG 519
           P G  G +GV G  GV GL G KGE G  G  G +G  G+ G  G  G IGP G  GP+G
Sbjct: 767 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 826

Query: 520 EPGLPGPPGFPG----IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575
             G  GP G PG     G+ G  G+ G PG PG  GP+G  G PG PG  G  G   V  
Sbjct: 827 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV-A 885

Query: 576 PTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
             P P+G+  P    G  G + P      KG +GG     P        P  PVG P
Sbjct: 886 GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 942



 Score =  297 bits (761), Expect = 2e-80
 Identities = 180/417 (43%), Positives = 210/417 (50%), Gaps = 79/417 (18%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV-------GKPGMPGMP 166
            G++G +G+ G  GPPGPPGL G     GI G  G+PGP+G  G+       G  G PG P
Sbjct: 1147 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1206

Query: 167  GKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG----------------LPGIGKP 210
            G  G  G+PG  GE G+ G++GPMG PGP GP GP G                + G+G+ 
Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266

Query: 211  GGPGLPGQPGP---------------KGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVK 254
            G PG  G PGP               KG+ GP G  GP G +GP GD G  G PG  G  
Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1326

Query: 255  GPPGMHGPPGPVGLPGVG----KPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQG-- 308
            G PG  G PGP G  GVG    + G  G PGP GP G+ G PG PG +GP G  G +G  
Sbjct: 1327 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1386

Query: 309  -------------PPGIPG-------IGKPGQDGIPGQPG------FPGGKGEQGLPGLP 342
                         PPG  G        GKPG +G+ G PG       PG  G+ G PG  
Sbjct: 1387 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1446

Query: 343  GPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM 401
            GPPGLPG+ G PG  G KG  G+ G+ G  G +GEKG  G PG  G PG  G  GIPGP 
Sbjct: 1447 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1506

Query: 402  GPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI 458
            GP   +G PGP G  G  GP+G  G  G  G +G  G PG  G  GPPG    P PI
Sbjct: 1507 GP---LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1560



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 14/31 (45%), Positives = 18/31 (58%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGHGIPGIKGK 148
            G++G  G PGP G PGPPG     +P +  K
Sbjct: 1534 GQKGDSGLPGPPGSPGPPGEVIQPLPILSSK 1564


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  441 bits (1135), Expect = e-124
 Identities = 293/705 (41%), Positives = 344/705 (48%), Gaps = 123/705 (17%)

Query: 47   QIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKE----YPHLPQYMKEIQPAPRMGKE 102
            ++ Q  P G+  P  P  + G   G   P  Q G++     P LP Y     P    G  
Sbjct: 761  EVGQIGPRGEDGPEGPKGRAG-PTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819

Query: 103  AVPKKGKEIPLASLRGEQGPRGEPGPRGP------------PGPPGLPGH----GIPGIK 146
              P    E     + G+ GPRG+ GP GP            PGP G  G     G PG +
Sbjct: 820  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879

Query: 147  GKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLP 205
            G  GPQG  G  G  G PG PGK G  G PG +GE G +G+ GP G  G  GP GP G  
Sbjct: 880  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 939

Query: 206  G-IGKPGGPGLPGQPGP------------KGDRGPKGLPG---PQGLRGPKGDKGF-GMP 248
            G IG+ G PG PG PG             KGD GP+G+ G   P GLRG  G++G  G  
Sbjct: 940  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 999

Query: 249  GAPGVKGPPGMHGPPGPVGLPG----------VGKPGVTGFPGPQGPLGKPGAPGEPGPQ 298
            GAPG+KG  G  GPPGPVG PG          +G PG  G  GP GP G+ GAPGE GPQ
Sbjct: 1000 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1059

Query: 299  GPIGVPGVQGPPGIPG----IGKPGQDGIPGQ---PGFPGGKGEQGLPGLPGPPGLPG-I 350
            GP G  GVQGP G+PG     G PG+DG  G+   PG  G KG++G  G PGPPGL G +
Sbjct: 1060 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1119

Query: 351  GKPG---------------------------FPGPKGDRGMGGVPGALGPRGEKG---PI 380
            G PG                           FPGP G  G+ G+PG  G +GE G   P+
Sbjct: 1120 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1179

Query: 381  GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP 440
            G PG  GP G  G  G  GP GPPG++G  G  GE G  G  G PGP GE G+ G  G+ 
Sbjct: 1180 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1239

Query: 441  GFLGE------VGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQ 494
            G  GE       GPPG +G PG  GPKG  G  G PG PG PG  GP G+ G+ GD+G  
Sbjct: 1240 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1299

Query: 495  GPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQ 553
            G PG PG  GPSG  GPPG PG +G PG  G  G  G  G  G AG  GPPGK G +GPQ
Sbjct: 1300 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1359

Query: 554  GQPGLPGP---------------------PGPPGPPGPPAV--MPPTPPPQGEYLPDMGL 590
            G  G PGP                      GPPGP GPP +  +   P  +GE      +
Sbjct: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1419

Query: 591  GIDGVKPPHAYGAKKGKNGGPAYE-MPAFTAE--LTAPFPPVGAP 632
            G+ G  PP   G +KG  G P  +  P    +  +  P  P+G P
Sbjct: 1420 GLIG--PPGEQG-EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1461



 Score =  434 bits (1115), Expect = e-121
 Identities = 284/642 (44%), Positives = 322/642 (50%), Gaps = 105/642 (16%)

Query: 37   PPQIPPQMPPQIPQYQPLG---QQVPHMPLAKDGLA-----------MGKEMPHLQYGKE 82
            PP  P +  PQ PQ  P+G    + P  P  KDGL             GK  P    G  
Sbjct: 872  PPGPPGERGPQGPQ-GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVV 930

Query: 83   YPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGP------------RG 130
             P  P    E  P    G    P    E  L    G++G +G+PGP            RG
Sbjct: 931  GPQGPT--GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 988

Query: 131  PPGPPGLPG-HGIPGIKGKPGPQGYPG-VGKPGMPG---------MPGKPGAMGMPGAKG 179
             PG  GLPG  G PG+KG  GPQG PG VG PG  G         +PG+PG  G PG  G
Sbjct: 989  FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1048

Query: 180  EIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP----------GLPGQPGPKGDRGPKG 229
            E G  GE GP G  G  G  GP GLPG   P G           G PGQ G KGD+G  G
Sbjct: 1049 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108

Query: 230  LPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHG------------PPGPVGLPGV-GKPG 275
             PGP GL+GP G  G  G  G PG +G  GM G            PPGP+GL G+ G PG
Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168

Query: 276  VTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG----IPGIGKPGQDGIPGQPGFPG 331
              G  G  GP+G PG PG  GPQGP G  G QGPPG    + G+G+ G+ G  G PG PG
Sbjct: 1169 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1228

Query: 332  G------------KGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGP 379
                         KGE G PG  GPPG  G   PG  GPKG+ G  G PG  GP GE GP
Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKG--PPGDDGPKGNPGPVGFPGDPGPPGEPGP 1286

Query: 380  IGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE------GGIVGPQGPPGPKGEPGL 433
             G  G+GG  GE G PG PGP GP G  G PGP G+       G  G QG  G KGE G 
Sbjct: 1287 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1346

Query: 434  QGFPGKPGFLG------EVGPPGMRGLPGPIGPKG---EAGQKGVPGLPGVPGLLGPKGE 484
            +G PGK G +G      + GP G+RG+PGP+G +G    AGQ G PG  G PGL G KG+
Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1406

Query: 485  PGIPGDQG------LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGV 537
            PG  G++G      L GPPG  G  G  G  G  G PG KG+ G+PGP G  G  G PG+
Sbjct: 1407 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1466

Query: 538  AGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPA-VMPPTP 578
             G  GP G  G+ GP GQ G  G PGPPG PGPP  V+ P P
Sbjct: 1467 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508



 Score =  419 bits (1078), Expect = e-117
 Identities = 264/611 (43%), Positives = 307/611 (50%), Gaps = 103/611 (16%)

Query: 92   EIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGP 151
            E  P   +G    P    +  +A + G  GP+G  GP+G PGPPG  G+  PG +G PGP
Sbjct: 608  EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN--PGPQGLPGP 665

Query: 152  QGYPG-------VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGL 204
            QG  G        GKPG+ G+PG  G  G PG +G+ G+KG +GP G  GP G PGP G+
Sbjct: 666  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 725

Query: 205  PGI-------------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP--- 248
             G              G+ G PG  G  G KGDRG  G  GP+G  GP+G KG   P   
Sbjct: 726  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 785

Query: 249  -------------GAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEP 295
                         G PG+ G PG  GP G  G PG   PG  G  G +G  GKPG  G+ 
Sbjct: 786  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF--PGANGEKGARGVAGKPGPRGQR 843

Query: 296  GPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG----I 350
            GP GP G  G +GP G PG  G  G DG PG PG  G +G QG  G PGP G PG     
Sbjct: 844  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903

Query: 351  GKPGFPGPKGDRGM---------GGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM 401
            G PG PG +G+ G          GGV G  GP GE GPIG  G  GPPG PG  G+PG  
Sbjct: 904  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963

Query: 402  GPPGAIGFPGPKGEGGIVGP---QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI 458
            G  GA G PGP+G  G  GP   +G PG +G PG QG PG  G  G  GPPG  G PG  
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023

Query: 459  GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGP---SGPIGPPGIP 515
            G  G AG  G+PG PG  G  GP GE G PG++G QGP G  G+ GP    GP GP G P
Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1083

Query: 516  ------------------GPKGEPGLPGPPGFPG-IGKPGVAGLHGPP---GKPGALGPQ 553
                              G KGE G PGPPG  G +G PG+AG  G P   G+ G  G +
Sbjct: 1084 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143

Query: 554  GQPGLPGPPGPPGP------PGPPA----------VMPPTPP-PQGEYLPDMGLGIDGVK 596
            G  G  G PGPPGP      PGPP           + PP PP P+G   P+   G DG +
Sbjct: 1144 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN---GADGPQ 1200

Query: 597  -PPHAYGAKKG 606
             PP + G+  G
Sbjct: 1201 GPPGSVGSVGG 1211



 Score =  418 bits (1074), Expect = e-116
 Identities = 268/637 (42%), Positives = 298/637 (46%), Gaps = 114/637 (17%)

Query: 97   PRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQG--- 153
            P M  E  P       +    G QGP G PG  G  GPPG P  G+PG  G PGP G   
Sbjct: 397  PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP--GLPGADGLPGPPGTML 454

Query: 154  -----YPGVGK--------------------------PGMPGMPGKPGAMGMPGAKGEIG 182
                 Y G G                           PG  G+ G+PG +G PG+ G  G
Sbjct: 455  MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 514

Query: 183  QKGEIGPMGIPGPQGPPGPHGLPG----IGKPGGPGLPGQPGPKGDRGPKGLP------- 231
            + G+ GP G  G QGPPGP G PG     G  GG G+PG+PG KGDRG  GLP       
Sbjct: 515  ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKG 574

Query: 232  -----GPQGLRGPKGDKG-------FGMPGAPGVKGPPGMHGPPGPVGLPG-VGKPGVTG 278
                 GPQG  GP GD G        G  G PG  GP G+ GP G  G PG  G  GV G
Sbjct: 575  HRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 634

Query: 279  FPGPQ---GPLGKPGAPGE---------PGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPG 325
             PGP+   GP G+PG PG+         PGPQGPIG PG +GP G PG+ G PG DG PG
Sbjct: 635  PPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 694

Query: 326  QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385
             PG  G  GE+G  G PGP      G  G+PGP+G +G  GV G  G +GEKG  G PG 
Sbjct: 695  HPGKEGQSGEKGALGPPGPQ-----GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF 749

Query: 386  GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445
             G  G  G  G  G +GP G  G  GPKG  G  G  GP G  GE G  G PG PG+ G 
Sbjct: 750  KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGR 809

Query: 446  VGPPGMRGLPGPIGPKGEAGQKGVPGLP------------GVPGLLGPKGEPGIPGDQGL 493
             GP G  G PG  G  GE G +GV G P            G  G  GP G+PG  G  G 
Sbjct: 810  QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGG 869

Query: 494  QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG-------------IGKPGVAGL 540
             GPPG PG  GP GP GP G PGPKG PG PG  G PG              G PG  G+
Sbjct: 870  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929

Query: 541  HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV-----MPPTPPPQGEYLPDMGLGIDGV 595
             GP G  G  GP G+ G PGPPGPPG  G P           P PQG    D   G+ G 
Sbjct: 930  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 989

Query: 596  KPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
                     +G  G    E P        P  PVG+P
Sbjct: 990  PGERGLPGAQGAPGLKGGEGP------QGPPGPVGSP 1020



 Score =  345 bits (885), Expect = 9e-95
 Identities = 229/537 (42%), Positives = 261/537 (48%), Gaps = 76/537 (14%)

Query: 163 PGMPGKPG----AMGMPGAKGEIGQKGEIGPM-------GIPGPQGPPGPHGLPGIGKPG 211
           PG+P +      ++   GA GE GQKGE   +       G PGP GP G  G PG+  P 
Sbjct: 364 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT 423

Query: 212 GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP---GAPGVKGPP----------- 257
           GP  PG PG +G  G  GLPG  GL GP G     +P   G  G KGP            
Sbjct: 424 GP--PGDPGDRGPPGRPGLPGADGLPGPPGTM-LMLPFRYGGDGSKGPTISAQEAQAQAI 480

Query: 258 ------GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311
                  + GPPGP+GL   G+PG  G PG  G  G+ G   +PGPQGP GV G  GP G
Sbjct: 481 LQQARIALRGPPGPMGL--TGRPGPVGGPGSSGAKGESG---DPGPQGPRGVQGPPGPTG 535

Query: 312 IPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGG 366
            PG  G+PG DG  G PG PG KG++G  GLPG PG  G     G  G PGP GD GM G
Sbjct: 536 KPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRG 595

Query: 367 VPGALGPRG---EKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG 423
             G +GPRG   E GP G  G  G PG PG PG+ G  GPPG  G  GP+GE G  G QG
Sbjct: 596 EDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG 655

Query: 424 PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGL------------------------PGPIG 459
            PGP+G PG QG  G PG  G  G PG+ GL                        PGP G
Sbjct: 656 NPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQG 715

Query: 460 PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKG 519
           P G  G +GV G  GV GL G KGE G  G  G +G  G+ G  G  G IGP G  GP+G
Sbjct: 716 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 775

Query: 520 EPGLPGPPGFPG----IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575
             G  GP G PG     G+ G  G+ G PG PG  GP+G  G PG PG  G  G   V  
Sbjct: 776 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV-A 834

Query: 576 PTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
             P P+G+  P    G  G + P      KG +GG     P        P  PVG P
Sbjct: 835 GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 891



 Score =  297 bits (761), Expect = 2e-80
 Identities = 180/417 (43%), Positives = 210/417 (50%), Gaps = 79/417 (18%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV-------GKPGMPGMP 166
            G++G +G+ G  GPPGPPGL G     GI G  G+PGP+G  G+       G  G PG P
Sbjct: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1155

Query: 167  GKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG----------------LPGIGKP 210
            G  G  G+PG  GE G+ G++GPMG PGP GP GP G                + G+G+ 
Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215

Query: 211  GGPGLPGQPGP---------------KGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVK 254
            G PG  G PGP               KG+ GP G  GP G +GP GD G  G PG  G  
Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1275

Query: 255  GPPGMHGPPGPVGLPGVG----KPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQG-- 308
            G PG  G PGP G  GVG    + G  G PGP GP G+ G PG PG +GP G  G +G  
Sbjct: 1276 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1335

Query: 309  -------------PPGIPG-------IGKPGQDGIPGQPG------FPGGKGEQGLPGLP 342
                         PPG  G        GKPG +G+ G PG       PG  G+ G PG  
Sbjct: 1336 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1395

Query: 343  GPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM 401
            GPPGLPG+ G PG  G KG  G+ G+ G  G +GEKG  G PG  G PG  G  GIPGP 
Sbjct: 1396 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1455

Query: 402  GPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI 458
            GP   +G PGP G  G  GP+G  G  G  G +G  G PG  G  GPPG    P PI
Sbjct: 1456 GP---LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1509



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 14/31 (45%), Positives = 18/31 (58%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGHGIPGIKGK 148
            G++G  G PGP G PGPPG     +P +  K
Sbjct: 1483 GQKGDSGLPGPPGSPGPPGEVIQPLPILSSK 1513


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  441 bits (1135), Expect = e-124
 Identities = 293/705 (41%), Positives = 344/705 (48%), Gaps = 123/705 (17%)

Query: 47   QIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKE----YPHLPQYMKEIQPAPRMGKE 102
            ++ Q  P G+  P  P  + G   G   P  Q G++     P LP Y     P    G  
Sbjct: 800  EVGQIGPRGEDGPEGPKGRAG-PTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858

Query: 103  AVPKKGKEIPLASLRGEQGPRGEPGPRGP------------PGPPGLPGH----GIPGIK 146
              P    E     + G+ GPRG+ GP GP            PGP G  G     G PG +
Sbjct: 859  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918

Query: 147  GKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLP 205
            G  GPQG  G  G  G PG PGK G  G PG +GE G +G+ GP G  G  GP GP G  
Sbjct: 919  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 978

Query: 206  G-IGKPGGPGLPGQPGP------------KGDRGPKGLPG---PQGLRGPKGDKGF-GMP 248
            G IG+ G PG PG PG             KGD GP+G+ G   P GLRG  G++G  G  
Sbjct: 979  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1038

Query: 249  GAPGVKGPPGMHGPPGPVGLPG----------VGKPGVTGFPGPQGPLGKPGAPGEPGPQ 298
            GAPG+KG  G  GPPGPVG PG          +G PG  G  GP GP G+ GAPGE GPQ
Sbjct: 1039 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1098

Query: 299  GPIGVPGVQGPPGIPG----IGKPGQDGIPGQ---PGFPGGKGEQGLPGLPGPPGLPG-I 350
            GP G  GVQGP G+PG     G PG+DG  G+   PG  G KG++G  G PGPPGL G +
Sbjct: 1099 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1158

Query: 351  GKPG---------------------------FPGPKGDRGMGGVPGALGPRGEKG---PI 380
            G PG                           FPGP G  G+ G+PG  G +GE G   P+
Sbjct: 1159 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1218

Query: 381  GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP 440
            G PG  GP G  G  G  GP GPPG++G  G  GE G  G  G PGP GE G+ G  G+ 
Sbjct: 1219 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1278

Query: 441  GFLGE------VGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQ 494
            G  GE       GPPG +G PG  GPKG  G  G PG PG PG  GP G+ G+ GD+G  
Sbjct: 1279 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1338

Query: 495  GPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQ 553
            G PG PG  GPSG  GPPG PG +G PG  G  G  G  G  G AG  GPPGK G +GPQ
Sbjct: 1339 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1398

Query: 554  GQPGLPGP---------------------PGPPGPPGPPAV--MPPTPPPQGEYLPDMGL 590
            G  G PGP                      GPPGP GPP +  +   P  +GE      +
Sbjct: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1458

Query: 591  GIDGVKPPHAYGAKKGKNGGPAYE-MPAFTAE--LTAPFPPVGAP 632
            G+ G  PP   G +KG  G P  +  P    +  +  P  P+G P
Sbjct: 1459 GLIG--PPGEQG-EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1500



 Score =  434 bits (1115), Expect = e-121
 Identities = 284/642 (44%), Positives = 322/642 (50%), Gaps = 105/642 (16%)

Query: 37   PPQIPPQMPPQIPQYQPLG---QQVPHMPLAKDGLA-----------MGKEMPHLQYGKE 82
            PP  P +  PQ PQ  P+G    + P  P  KDGL             GK  P    G  
Sbjct: 911  PPGPPGERGPQGPQ-GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVV 969

Query: 83   YPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGP------------RG 130
             P  P    E  P    G    P    E  L    G++G +G+PGP            RG
Sbjct: 970  GPQGPT--GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1027

Query: 131  PPGPPGLPG-HGIPGIKGKPGPQGYPG-VGKPGMPG---------MPGKPGAMGMPGAKG 179
             PG  GLPG  G PG+KG  GPQG PG VG PG  G         +PG+PG  G PG  G
Sbjct: 1028 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1087

Query: 180  EIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGP----------GLPGQPGPKGDRGPKG 229
            E G  GE GP G  G  G  GP GLPG   P G           G PGQ G KGD+G  G
Sbjct: 1088 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147

Query: 230  LPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHG------------PPGPVGLPGV-GKPG 275
             PGP GL+GP G  G  G  G PG +G  GM G            PPGP+GL G+ G PG
Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207

Query: 276  VTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG----IPGIGKPGQDGIPGQPGFPG 331
              G  G  GP+G PG PG  GPQGP G  G QGPPG    + G+G+ G+ G  G PG PG
Sbjct: 1208 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1267

Query: 332  G------------KGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGP 379
                         KGE G PG  GPPG  G   PG  GPKG+ G  G PG  GP GE GP
Sbjct: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKG--PPGDDGPKGNPGPVGFPGDPGPPGEPGP 1325

Query: 380  IGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE------GGIVGPQGPPGPKGEPGL 433
             G  G+GG  GE G PG PGP GP G  G PGP G+       G  G QG  G KGE G 
Sbjct: 1326 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1385

Query: 434  QGFPGKPGFLG------EVGPPGMRGLPGPIGPKG---EAGQKGVPGLPGVPGLLGPKGE 484
            +G PGK G +G      + GP G+RG+PGP+G +G    AGQ G PG  G PGL G KG+
Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1445

Query: 485  PGIPGDQG------LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGV 537
            PG  G++G      L GPPG  G  G  G  G  G PG KG+ G+PGP G  G  G PG+
Sbjct: 1446 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1505

Query: 538  AGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPA-VMPPTP 578
             G  GP G  G+ GP GQ G  G PGPPG PGPP  V+ P P
Sbjct: 1506 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547



 Score =  419 bits (1078), Expect = e-117
 Identities = 264/611 (43%), Positives = 307/611 (50%), Gaps = 103/611 (16%)

Query: 92   EIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGP 151
            E  P   +G    P    +  +A + G  GP+G  GP+G PGPPG  G+  PG +G PGP
Sbjct: 647  EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN--PGPQGLPGP 704

Query: 152  QGYPG-------VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGL 204
            QG  G        GKPG+ G+PG  G  G PG +G+ G+KG +GP G  GP G PGP G+
Sbjct: 705  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 764

Query: 205  PGI-------------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP--- 248
             G              G+ G PG  G  G KGDRG  G  GP+G  GP+G KG   P   
Sbjct: 765  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 824

Query: 249  -------------GAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEP 295
                         G PG+ G PG  GP G  G PG   PG  G  G +G  GKPG  G+ 
Sbjct: 825  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF--PGANGEKGARGVAGKPGPRGQR 882

Query: 296  GPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG----I 350
            GP GP G  G +GP G PG  G  G DG PG PG  G +G QG  G PGP G PG     
Sbjct: 883  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942

Query: 351  GKPGFPGPKGDRGM---------GGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM 401
            G PG PG +G+ G          GGV G  GP GE GPIG  G  GPPG PG  G+PG  
Sbjct: 943  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002

Query: 402  GPPGAIGFPGPKGEGGIVGP---QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI 458
            G  GA G PGP+G  G  GP   +G PG +G PG QG PG  G  G  GPPG  G PG  
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062

Query: 459  GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGP---SGPIGPPGIP 515
            G  G AG  G+PG PG  G  GP GE G PG++G QGP G  G+ GP    GP GP G P
Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1122

Query: 516  ------------------GPKGEPGLPGPPGFPG-IGKPGVAGLHGPP---GKPGALGPQ 553
                              G KGE G PGPPG  G +G PG+AG  G P   G+ G  G +
Sbjct: 1123 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182

Query: 554  GQPGLPGPPGPPGP------PGPPA----------VMPPTPP-PQGEYLPDMGLGIDGVK 596
            G  G  G PGPPGP      PGPP           + PP PP P+G   P+   G DG +
Sbjct: 1183 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN---GADGPQ 1239

Query: 597  -PPHAYGAKKG 606
             PP + G+  G
Sbjct: 1240 GPPGSVGSVGG 1250



 Score =  418 bits (1074), Expect = e-116
 Identities = 268/637 (42%), Positives = 298/637 (46%), Gaps = 114/637 (17%)

Query: 97   PRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQG--- 153
            P M  E  P       +    G QGP G PG  G  GPPG P  G+PG  G PGP G   
Sbjct: 436  PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP--GLPGADGLPGPPGTML 493

Query: 154  -----YPGVGK--------------------------PGMPGMPGKPGAMGMPGAKGEIG 182
                 Y G G                           PG  G+ G+PG +G PG+ G  G
Sbjct: 494  MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 553

Query: 183  QKGEIGPMGIPGPQGPPGPHGLPG----IGKPGGPGLPGQPGPKGDRGPKGLP------- 231
            + G+ GP G  G QGPPGP G PG     G  GG G+PG+PG KGDRG  GLP       
Sbjct: 554  ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKG 613

Query: 232  -----GPQGLRGPKGDKG-------FGMPGAPGVKGPPGMHGPPGPVGLPG-VGKPGVTG 278
                 GPQG  GP GD G        G  G PG  GP G+ GP G  G PG  G  GV G
Sbjct: 614  HRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 673

Query: 279  FPGPQ---GPLGKPGAPGE---------PGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPG 325
             PGP+   GP G+PG PG+         PGPQGPIG PG +GP G PG+ G PG DG PG
Sbjct: 674  PPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG 733

Query: 326  QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385
             PG  G  GE+G  G PGP      G  G+PGP+G +G  GV G  G +GEKG  G PG 
Sbjct: 734  HPGKEGQSGEKGALGPPGPQ-----GPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF 788

Query: 386  GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445
             G  G  G  G  G +GP G  G  GPKG  G  G  GP G  GE G  G PG PG+ G 
Sbjct: 789  KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGR 848

Query: 446  VGPPGMRGLPGPIGPKGEAGQKGVPGLP------------GVPGLLGPKGEPGIPGDQGL 493
             GP G  G PG  G  GE G +GV G P            G  G  GP G+PG  G  G 
Sbjct: 849  QGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGG 908

Query: 494  QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG-------------IGKPGVAGL 540
             GPPG PG  GP GP GP G PGPKG PG PG  G PG              G PG  G+
Sbjct: 909  DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968

Query: 541  HGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV-----MPPTPPPQGEYLPDMGLGIDGV 595
             GP G  G  GP G+ G PGPPGPPG  G P           P PQG    D   G+ G 
Sbjct: 969  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF 1028

Query: 596  KPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
                     +G  G    E P        P  PVG+P
Sbjct: 1029 PGERGLPGAQGAPGLKGGEGP------QGPPGPVGSP 1059



 Score =  345 bits (885), Expect = 9e-95
 Identities = 229/537 (42%), Positives = 261/537 (48%), Gaps = 76/537 (14%)

Query: 163 PGMPGKPG----AMGMPGAKGEIGQKGEIGPM-------GIPGPQGPPGPHGLPGIGKPG 211
           PG+P +      ++   GA GE GQKGE   +       G PGP GP G  G PG+  P 
Sbjct: 403 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT 462

Query: 212 GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP---GAPGVKGPP----------- 257
           GP  PG PG +G  G  GLPG  GL GP G     +P   G  G KGP            
Sbjct: 463 GP--PGDPGDRGPPGRPGLPGADGLPGPPGTM-LMLPFRYGGDGSKGPTISAQEAQAQAI 519

Query: 258 ------GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311
                  + GPPGP+GL   G+PG  G PG  G  G+ G   +PGPQGP GV G  GP G
Sbjct: 520 LQQARIALRGPPGPMGL--TGRPGPVGGPGSSGAKGESG---DPGPQGPRGVQGPPGPTG 574

Query: 312 IPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGG 366
            PG  G+PG DG  G PG PG KG++G  GLPG PG  G     G  G PGP GD GM G
Sbjct: 575 KPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRG 634

Query: 367 VPGALGPRG---EKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG 423
             G +GPRG   E GP G  G  G PG PG PG+ G  GPPG  G  GP+GE G  G QG
Sbjct: 635 EDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG 694

Query: 424 PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGL------------------------PGPIG 459
            PGP+G PG QG  G PG  G  G PG+ GL                        PGP G
Sbjct: 695 NPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQG 754

Query: 460 PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKG 519
           P G  G +GV G  GV GL G KGE G  G  G +G  G+ G  G  G IGP G  GP+G
Sbjct: 755 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 814

Query: 520 EPGLPGPPGFPG----IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575
             G  GP G PG     G+ G  G+ G PG PG  GP+G  G PG PG  G  G   V  
Sbjct: 815 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV-A 873

Query: 576 PTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
             P P+G+  P    G  G + P      KG +GG     P        P  PVG P
Sbjct: 874 GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 930



 Score =  297 bits (761), Expect = 2e-80
 Identities = 180/417 (43%), Positives = 210/417 (50%), Gaps = 79/417 (18%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV-------GKPGMPGMP 166
            G++G +G+ G  GPPGPPGL G     GI G  G+PGP+G  G+       G  G PG P
Sbjct: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1194

Query: 167  GKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHG----------------LPGIGKP 210
            G  G  G+PG  GE G+ G++GPMG PGP GP GP G                + G+G+ 
Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254

Query: 211  GGPGLPGQPGP---------------KGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVK 254
            G PG  G PGP               KG+ GP G  GP G +GP GD G  G PG  G  
Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1314

Query: 255  GPPGMHGPPGPVGLPGVG----KPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQG-- 308
            G PG  G PGP G  GVG    + G  G PGP GP G+ G PG PG +GP G  G +G  
Sbjct: 1315 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1374

Query: 309  -------------PPGIPG-------IGKPGQDGIPGQPG------FPGGKGEQGLPGLP 342
                         PPG  G        GKPG +G+ G PG       PG  G+ G PG  
Sbjct: 1375 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1434

Query: 343  GPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM 401
            GPPGLPG+ G PG  G KG  G+ G+ G  G +GEKG  G PG  G PG  G  GIPGP 
Sbjct: 1435 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1494

Query: 402  GPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI 458
            GP   +G PGP G  G  GP+G  G  G  G +G  G PG  G  GPPG    P PI
Sbjct: 1495 GP---LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1548



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 14/31 (45%), Positives = 18/31 (58%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGHGIPGIKGK 148
            G++G  G PGP G PGPPG     +P +  K
Sbjct: 1522 GQKGDSGLPGPPGSPGPPGEVIQPLPILSSK 1552


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  431 bits (1109), Expect = e-121
 Identities = 278/666 (41%), Positives = 318/666 (47%), Gaps = 135/666 (20%)

Query: 82   EYPHLPQYMKEIQPAP----RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPR------GP 131
            EYP   Q+  +I P        G+ AV +KG++         +GP G PGP+      GP
Sbjct: 359  EYPSRTQF--QIFPGAGEKGAKGEPAVIEKGQQF--------EGPPGAPGPQGVVGPSGP 408

Query: 132  PGPPGLPGH-------GIPGIKGKPGPQGYPGV--------------------------- 157
            PGPPG PG        G+PGI G  G +G PG                            
Sbjct: 409  PGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQA 468

Query: 158  ----------GKPGMPGMPGKPGAMGM---PGAKGEIGQKGEIGPMGIPGPQGPPGPHGL 204
                      G PG  G+ G+PG +G+   PG KGE G +G  GP G+ GP GPPG  G 
Sbjct: 469  VLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGK 528

Query: 205  PG-IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGP 262
             G  G  G  GLPG  GPKGDRG  GLPG  G +G +GD G  G PG PG  G  G  GP
Sbjct: 529  MGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGP 588

Query: 263  PGPVGLPG----------------VGKPGVTGF---PGPQGPLGKPGAPGE--------- 294
            PGP G  G                 G+PGVTG    PG +G +G PG PG          
Sbjct: 589  PGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS 648

Query: 295  ---PGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI 350
               PGPQG IG PG +GPPG PGI G PG DG  G PG  G  GE+G  G PG       
Sbjct: 649  QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPG-----SA 703

Query: 351  GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410
            G PG+PGP+G +G  G  G  G +GEKG  G PG  G  G  G  G PG  GP G  G  
Sbjct: 704  GPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPE 763

Query: 411  GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470
            GPKG+ G  G +GPPG  GE G  G PG PG+ G  GP G  G PGP+GP GE G+ G  
Sbjct: 764  GPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKT 823

Query: 471  GLPGVPGLLGP------------KGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPK 518
            G PG+ G  GP             G+PG  GD G  G PGIPG  G  G  GPPG PGPK
Sbjct: 824  GQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPK 883

Query: 519  GEPGLPGPPGFPG-------------IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP 565
            G PG  G  G PG              G PG AG+ GP GK G +GP G+ G PGPPGPP
Sbjct: 884  GPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPP 943

Query: 566  GPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAP 625
            G  G P  +      +GE  P   LG +G   P       G  GGP    P        P
Sbjct: 944  GEQGLPG-LEGREGAKGELGPPGPLGKEG---PAGLRGFPGPKGGPGDPGPTGLKGDKGP 999

Query: 626  FPPVGA 631
              PVGA
Sbjct: 1000 PGPVGA 1005



 Score =  413 bits (1061), Expect = e-115
 Identities = 296/758 (39%), Positives = 347/758 (45%), Gaps = 190/758 (25%)

Query: 53   PLGQQVPHMPLAKDGLAMGKEMPHLQYGKE----YPHLPQYMKEIQPAPRMGKEA----V 104
            P G+  P  P  + G A G+E P    G++     P LP Y     P   +G       +
Sbjct: 756  PRGEDGPEGPKGQAGQA-GEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPI 814

Query: 105  PKKGK--EIPLASLRGEQGP------RGEPGPRGPPGP---------PGLPGH-GIPGIK 146
             +KGK  +     L GE+GP      RG+PG  G PGP         PG+PG  G+PG++
Sbjct: 815  GEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQ 874

Query: 147  GKPG---PQGYPG-VGKPGMPGMPGK------------PGAMGMPGAKGEIGQKGEIGPM 190
            G PG   P+G PG  GK G PG PG+            PG  G+ G +G+ G+ G +G  
Sbjct: 875  GPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGER 934

Query: 191  GIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGPKGL---PGPQGLRGPKGDKGF- 245
            G PGP GPPG  GLPG+ G+ G  G  G PGP G  GP GL   PGP+G  G  G  G  
Sbjct: 935  GPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLK 994

Query: 246  ---GMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302
               G PG  G  G PG  GP GP G  G+G PG +G  GP GP GK G+ GE GP GP G
Sbjct: 995  GDKGPPGPVGANGSPGERGPLGPAG--GIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTG 1052

Query: 303  ---VPGVQGPPGIPGIGKP-GQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPG 354
               +PG  GP G PG   P G++G  G  G PG KG +G  G  GPPG PGI    G PG
Sbjct: 1053 KDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPG 1112

Query: 355  FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKG 414
             PG  G +G  G PG  G +G+ G  G  G+ GPPG  GLPG PG  G  G +G  GP G
Sbjct: 1113 PPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHG 1172

Query: 415  EGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVG---------PPGMRGLPGPIG------ 459
              G  GPQGP G +G PGL G  G+PG +GE G         PPG  G+PGP G      
Sbjct: 1173 APGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKG 1232

Query: 460  ---------------PKGEAGQKGVPGLPGVPGLLGPKGEPGI------------PGDQG 492
                           P GE G KG  G  G+PG LGP G+PG+            PGD G
Sbjct: 1233 DSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVG 1292

Query: 493  LQGPPGI---------PGIGGPSG------------------PIGPPG------------ 513
              GPPG          PG  GPSG                  P GPPG            
Sbjct: 1293 GPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPG 1352

Query: 514  ---------IPGPKGEPGLPGPPG------------FPGI----------GKPGVAGLHG 542
                     IPGP GEPGL G PG             PG+          G  G+ GL G
Sbjct: 1353 RVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIG 1412

Query: 543  PPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYG 602
            PPG+ G  G QG PG+ GPPGP G PGPP              P   LG  G  PP   G
Sbjct: 1413 PPGEAGEKGDQGLPGVQGPPGPKGDPGPPG-------------PIGSLGHPG--PPGVAG 1457

Query: 603  --AKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKL 638
               +KG  G P    P        P  P GAP + + L
Sbjct: 1458 PLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGL 1495



 Score =  408 bits (1049), Expect = e-114
 Identities = 257/636 (40%), Positives = 303/636 (47%), Gaps = 110/636 (17%)

Query: 84   PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPR------GPPGPPGL 137
            P LP    +      +G+   P +  E       G  G  GEPGPR      G PGP G 
Sbjct: 556  PGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGR 615

Query: 138  PG----HGIPGIKGKPGPQGYPG----------------------------VGKPGMPGM 165
            PG     G PG KG  GP G PG                             G PG+PG+
Sbjct: 616  PGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGL 675

Query: 166  PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-------------GKPGG 212
            PG  G +G PG +G  G+KG  GP G  GP G PGP G+ G              G+ G 
Sbjct: 676  PGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGF 735

Query: 213  PGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV- 271
            PG  G  G KGD+G  G PGP+G  GP+G K  G  G  G +GPPG  G  G +G+PG+ 
Sbjct: 736  PGFKGDVGLKGDQGKPGAPGPRGEDGPEGPK--GQAGQAGEEGPPGSAGEKGKLGVPGLP 793

Query: 272  ------GKPGVTGFPGPQGPL---GKPGAPGEPGPQGPIGVPGVQGPPGIPG-IGKPGQD 321
                  G  G  GFPGP GP+   GK G  G+PG +G  G PG +G  G PG  G+PG  
Sbjct: 794  GYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPK 853

Query: 322  GIPGQPGFPGGKGEQGLPGLPGPPGLPG----------IGKPGFPGPKGDRGM------G 365
            G  GQ G PG  GE+GLPGL GPPG PG           G+PG PG +G+ G        
Sbjct: 854  GDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPP 913

Query: 366  GVPGALGPRGEKGPI------GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV 419
            G  G LGP+G+ G +      G PG  GPPGE GLPG+ G  G  G +G PGP G+ G  
Sbjct: 914  GPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPA 973

Query: 420  GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLL 479
            G +G PGPKG PG  G  G  G  G  GP G  G PG  GP G AG  G+PG  G  G +
Sbjct: 974  GLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPV 1033

Query: 480  GPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG-IGKPGVA 538
            GP G+ G  G++G  GP G  GI GP GP+GPPG  GP GE G  G  G PG  G  G  
Sbjct: 1034 GPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDK 1093

Query: 539  GLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP----------------------P 576
            G  GPPG+PG  GP G PG PG  G  G  GPP +                        P
Sbjct: 1094 GDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLP 1153

Query: 577  TPPPQGEYLPDMG-LGIDGVKPPHAYGAKKGKNGGP 611
             PP +   + D+G +G  G   P       G  G P
Sbjct: 1154 GPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTP 1189



 Score =  400 bits (1029), Expect = e-111
 Identities = 247/538 (45%), Positives = 283/538 (52%), Gaps = 41/538 (7%)

Query: 113  LASLRGEQGPRGEPGPRGPPGPPGLPGH-------GIPGIKGKPGPQGYPGV-GKPGMPG 164
            L  L GE+G RG+ G  G PGPPG  G        G  G  G+PGP+G  G  G PG  G
Sbjct: 555  LPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTG 614

Query: 165  MPGKPGAMGMPGAKGEIGQKGEIGP---MGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPG 220
             PG  G  G PGAKG +G  GE GP    G  G QG PGP GL G  G+ G PG PG PG
Sbjct: 615  RPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPG 674

Query: 221  PKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPG-VGKPGVTG 278
              G  GP G PG +G  G KG +G  G  G PG  GP G+ G  G  GL G  G+ G  G
Sbjct: 675  LPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDG 734

Query: 279  FPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGL 338
            FPG +G +G  G  G+PG  GP G  G +GP      G+ GQ G  G PG  G KG+ G+
Sbjct: 735  FPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPK-----GQAGQAGEEGPPGSAGEKGKLGV 789

Query: 339  PGLPGPPGLPG----IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGL 394
            PGLPG PG PG    IG PG  GP G++G  G  G  G  GE+GP G+ G  G PG  G 
Sbjct: 790  PGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQ 849

Query: 395  PGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP---------GFLGE 445
            PG  G +G  GA G PG KG  G+ GP G PGPKG PG QG  G+P         GF G+
Sbjct: 850  PGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQ 909

Query: 446  VGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGP 505
             GPPG  G+ GP G  GE G  G  G PG PG  G +G PG+ G +G +G  G PG  G 
Sbjct: 910  TGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGK 969

Query: 506  SGPIGPPGIPGPKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGP 564
             GP G  G PGPKG PG PGP G  G  G PG  G +G PG+ G LGP G  GLPG  G 
Sbjct: 970  EGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGS 1029

Query: 565  PGPPGPPAVM-------PPTPPPQGEYLPDMG-LGIDGVKPPHAYGAKKGKNGGPAYE 614
             GP GP           PP P  +      +G LG  G   P      KG  G P ++
Sbjct: 1030 EGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHK 1087



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 113  LASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPG-VGKPGMPGMPGKPG 170
            L  ++G  GP+G+PGP GP G  G PG  G+ G  G+ G +G PG +G  G  G  G PG
Sbjct: 1425 LPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPG 1484

Query: 171  AMGMPGAKGEIGQKGEIGPMGIPGPQG 197
              G P     + ++    P+ +P  +G
Sbjct: 1485 PPGAPAELHGLRRRRRFVPVPLPVVEG 1511


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score =  431 bits (1108), Expect = e-120
 Identities = 281/678 (41%), Positives = 319/678 (47%), Gaps = 123/678 (18%)

Query: 53  PLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIP 112
           P+G   P  P    G A G +    Q     P  P     + P    G    P    E  
Sbjct: 202 PMGPMGPRGPPGPAG-APGPQ--GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258

Query: 113 LASLRGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPGPQGYPGV-GKPGMPGMPG 167
                GE+GP G  G RG PG PGLPG     G PG+ G  G  G PGV G+ G PG  G
Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 318

Query: 168 KPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGLPGQPGPKGDRG 226
            PG MG  G  GE G+ G  G  G  G  G PGP G PG +G  GGPG PG PG KG+ G
Sbjct: 319 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 378

Query: 227 PKGLPGPQGLRGPKGDKGF-------------------------------GMPGAPGVKG 255
           P G  GP+G +GP+G+ G                                G PG PG +G
Sbjct: 379 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 438

Query: 256 PPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG 314
           PPG  G  GP+G  G  G+PG+ GF G QGP G+PG  G  G  GP G  G +G  G PG
Sbjct: 439 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498

Query: 315 ----IGKPGQDGIPGQPGFPGGKG---EQGLPGLPGPPGLPGI-------GKPGFPGPKG 360
               IG PG+ G PG  GFPG  G    +G PG  GP GL G        G+PG PG  G
Sbjct: 499 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558

Query: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM---GPPGAIGFPGPKGEGG 417
            RG+ G PG  GP+G+ GP GAPG      E G PG PGP    G PG +GFPGPKG  G
Sbjct: 559 ARGLTGRPGDAGPQGKVGPSGAPG------EDGRPGPPGPQGARGQPGVMGFPGPKGANG 612

Query: 418 IVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPP------------------GMRGLPGPIG 459
             G  G  G  G PGL+G PGK G  G  GPP                  G +GLPGP G
Sbjct: 613 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG 672

Query: 460 PKGEAGQ---KGVPGLPGVPGLLGPKGEPGIPGD------QGLQGP---PGIPGIGGP-- 505
           P GE G+   +GVPG  G PGL+GP+GE G PG+      QGLQGP   PG PG  GP  
Sbjct: 673 PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 732

Query: 506 -SGPIGPPGIPGPKGEPGLPGPPGFPGI-------------------GKPGVAGLHGPPG 545
            SGP GPPG  GP G  G+PG  G  GI                   GK G  GL GP G
Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 792

Query: 546 KPGALGPQGQPGLPGPPGPP------GPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPH 599
            PG  G  G+ G  GPPGP       G PG      P P P G   P    G  G K   
Sbjct: 793 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP-PGPAGFAGPPGADGQPGAKGEQ 851

Query: 600 AYGAKKGKNGGPAYEMPA 617
               +KG  G P  + P+
Sbjct: 852 GEAGQKGDAGAPGPQGPS 869



 Score =  421 bits (1082), Expect = e-117
 Identities = 255/560 (45%), Positives = 286/560 (51%), Gaps = 66/560 (11%)

Query: 114  ASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGA 171
            A  +G+ GP G PG  G PGPPG  G  G PG+ G PGP+G  G  GK G  G+PG PG 
Sbjct: 569  AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 628

Query: 172  MGMPGAKGEIGQKGEIGP------------------MGIPGPQGPPGPHGLPGI-GKPGG 212
             G+PG  GE G  G  GP                   G+PGP GPPG  G PG  G PG 
Sbjct: 629  RGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGE 688

Query: 213  PGLPGQPGPKGDRG---PKGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPGMHGPPGP 265
             G PG  GP+G+RG    +G PG QGL+GP+G  G     G  GA G  GPPG  GPPG 
Sbjct: 689  AGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 748

Query: 266  VGLPG----------------VGKPGVTGFPG------------PQGPLGKPGAPGEPGP 297
             G+PG                VG+ G  G PG            P GP G  G  GE GP
Sbjct: 749  QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP 808

Query: 298  QGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGF---PGGKGEQGLPGLPGPPGLPGI-GK 352
             GP G  G +G PG  G  G PG  G  G PG    PG KGEQG  G  G  G PG  G 
Sbjct: 809  PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 868

Query: 353  PGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGP 412
             G PGP+G  G+ G  GA G +G  G  G PG  G  G PG  G PGP GPPG  G  GP
Sbjct: 869  SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGP 928

Query: 413  KGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGL 472
            KG  G     GPPG  GEPGLQG  G PG  GE G  G  G  GP GP+G AGQ+G+ GL
Sbjct: 929  KGARG---DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 985

Query: 473  PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG- 531
            PG  G  G  G PG  G+ G QG PG  G  GP GP+GPPG+ GP GEPG  G PG  G 
Sbjct: 986  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 1045

Query: 532  IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLG 591
             G+ G AG+ G  G+ GA+G  G PG PG PGP GP G           QG   P    G
Sbjct: 1046 PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA-GAQGPMGPSGPAG 1104

Query: 592  IDGVKPPHAYGAKKGKNGGP 611
              G++ P      KG+ G P
Sbjct: 1105 ARGIQGPQGPRGDKGEAGEP 1124



 Score =  421 bits (1081), Expect = e-117
 Identities = 252/544 (46%), Positives = 284/544 (52%), Gaps = 81/544 (14%)

Query: 100  GKEAVPKKGKEIPLASLRGEQG---PRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYP 155
            G + VP +     L   RGE+G    RG PG +G  GP GLPG  G  G KG  GP G P
Sbjct: 681  GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 740

Query: 156  GV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG---------PQGPPGPHGLP 205
            G  G PG+ GMPG+ GA G+ G KG+ G  GE GP G PG         P GPPGP G  
Sbjct: 741  GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 800

Query: 206  G----IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGP---------KGDKGF----GMP 248
            G    +G PG  G  G  G  G+RG  G PGP G  GP         KG++G     G  
Sbjct: 801  GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 860

Query: 249  GAPGVKGPPGMHGPPGPVGLPGV-------GKPGVTGFPGPQGPLGKPGAPGEPGPQGP- 300
            GAPG +GP G  GP GP G+ G        G PG TGFPG  G +G PG+ G PGP GP 
Sbjct: 861  GAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP 920

Query: 301  --------------------IGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLP 339
                                 G PG+QGP G PG  G+PG DG  G  G PG +G  G  
Sbjct: 921  GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 980

Query: 340  GLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP 398
            G+ G PG  G  G PG PGP G+ G  G PGA G RG  GP+G PG+ GP GEPG  G P
Sbjct: 981  GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 1040

Query: 399  GPMGPP---GAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV--------- 446
            G  GPP   GA G  G +GE G VG  G PGP G PG  G  GK G  GE          
Sbjct: 1041 GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS 1100

Query: 447  GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506
            GP G RG+ GP GP+G+ G+ G PG  G+ G  G  G  G+PG  G  G  G  G  GPS
Sbjct: 1101 GPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS 1160

Query: 507  GPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPG 566
            GP GPPG  GP G+ G  G PG   IG P      GP G+ G  GP G PG PGPPGPPG
Sbjct: 1161 GPRGPPGPVGPSGKDGANGIPG--PIGPP------GPRGRSGETGPAGPPGNPGPPGPPG 1212

Query: 567  PPGP 570
            PPGP
Sbjct: 1213 PPGP 1216



 Score =  418 bits (1075), Expect = e-117
 Identities = 250/565 (44%), Positives = 278/565 (49%), Gaps = 78/565 (13%)

Query: 118 GEQGPRGEPGPRGPPGPPGLPG----------------------------------HGIP 143
           GE G  G PGP GPPGPPG PG                                   G P
Sbjct: 153 GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212

Query: 144 GIKGKPGPQGYPG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPH 202
           G  G PGPQG+ G  G+PG PG+ G  G  G PG  G+ G  GE G  G  G +GPPGP 
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 203 GLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPG 258
           G  G   PG PGLPG  G +G  G  G  G  G  G KG+ G     G PG  G +G PG
Sbjct: 273 GARGF--PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG 330

Query: 259 MHGPPGPVGLPGV----GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG 314
             G  GP G  G     G+PG  G PGP GP G PG PG PG +G  G  G +GP G  G
Sbjct: 331 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG 390

Query: 315 -IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALG 372
             G+PG  G PG  G  G  G  G+PG  G  G PGI G PGFPGP+G  G  G  G LG
Sbjct: 391 PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 450

Query: 373 PRGEKGPIGAPGI---GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKG 429
           P+G+ G  G  G     GP GEPG  G  G  GP G  G  G +GE G VGP GPPG +G
Sbjct: 451 PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERG 510

Query: 430 EPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPG 489
            PG +GFPG+ G  G  G PG RG  G  GPKG  G  G PG PG+PG  G  G PG  G
Sbjct: 511 APGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAG 570

Query: 490 DQGLQGPPGIPGIGGPSGPIGPP---------GIPGPK---------GEPGLPGPPGFPG 531
            QG  GP G PG  G  GP GP          G PGPK         GE GLPG PG  G
Sbjct: 571 PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG 630

Query: 532 I-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGL 590
           + GK G  G  GPPG  G  G +G+ G PGP G  G PGPP      PP +G    D G+
Sbjct: 631 LPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG-----PPGEGGKPGDQGV 685

Query: 591 ----GIDGVKPPHAYGAKKGKNGGP 611
               G  G+  P       G+ G P
Sbjct: 686 PGEAGAPGLVGPRGERGFPGERGSP 710



 Score =  406 bits (1043), Expect = e-113
 Identities = 258/577 (44%), Positives = 278/577 (48%), Gaps = 104/577 (18%)

Query: 114  ASLRGEQGPRGEPGPRGPPGPPGLPGHG-IPGIKGKPGPQGYPGV----GKPGMPGMPGK 168
            A  RGEQG  G  G +G PGPPG PG G  PG +G PG  G PG+    G+ G PG  G 
Sbjct: 650  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 709

Query: 169  PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGP 227
            PGA G+ G +G  G  G  GP G  GP GPPG  G PG+ G PG  G  G  GPKGDRG 
Sbjct: 710  PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769

Query: 228  KGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPGMHGPPGPVGLPGV----------GK 273
             G  GP+G  G  G +G     G PG  G  G  G  GPPGP G  G           G 
Sbjct: 770  VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 829

Query: 274  PGVTGFPGPQGPLGKPGAPGE------------PGPQGPIGVPGVQGPPGIPGI-GKPGQ 320
            PG  GF GP G  G+PGA GE            PGPQGP G PG QGP G+ G  G  G 
Sbjct: 830  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889

Query: 321  DGIPGQPGFPGGKGEQGLPGL---PGPPGLPG-------------------IGKPGFPGP 358
             G PG  GFPG  G  G PG    PGPPG PG                    G+PG  GP
Sbjct: 890  QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 949

Query: 359  KGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG---------EPGLPGIPGPMGPPGAIGF 409
             G  G  G PG  GP G +GP G  G+ G  G         E G PG+PGP G PG  G 
Sbjct: 950  AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 410  PGPKGEGGIVGPQGPPG---PKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ 466
            PG  G+ G  GP GPPG   P GEPG +G PG  G      PPG  G  G  G +GE G 
Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG------PPGRDGAAGVKGDRGETGA 1063

Query: 467  KGVPGLPGVPGLLGPKGEPGIPGD------QGLQGPPGIPGIGGPSGPIGPPGIPGPKGE 520
             G PG PG PG  GP G  G  GD      QG  GP G  G  G  GP GP G  G  GE
Sbjct: 1064 VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE 1123

Query: 521  PG---------------LPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGP 564
            PG               LPGPPG  G  G  G AG  GP G PG +GP G+ G  G PGP
Sbjct: 1124 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP 1183

Query: 565  PGPPGP--------PAVMPPTPPPQGEYLPDMGLGID 593
             GPPGP        PA  P  P P G   P  G GID
Sbjct: 1184 IGPPGPRGRSGETGPAGPPGNPGPPGPPGPP-GPGID 1219



 Score =  248 bits (634), Expect = 1e-65
 Identities = 153/354 (43%), Positives = 170/354 (48%), Gaps = 55/354 (15%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV-------------GKP 160
            G  GP+G  G +GPPG  G PG     G PG  G PGP G PG              G P
Sbjct: 879  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938

Query: 161  GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQP 219
            G  G PG  G  G PG KGE G  G  G  G PGPQG  G  G+ G+ G+ G  G PG P
Sbjct: 939  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998

Query: 220  GPKGDRGPKGLPGPQGLRGPKGDKG----FGMPGAPGVKGPPGMHGPPGPVGLPGV---- 271
            GP G+ G +G PG  G RGP G  G     G  G PG +G PG  GPPG  G  GV    
Sbjct: 999  GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 1058

Query: 272  ---------GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----GKP 318
                     G PG  G PGP GP GK G  GE G QGP+G  G  G  GI G     G  
Sbjct: 1059 GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDK 1118

Query: 319  GQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-------------GKPGFPGPKGDRGMG 365
            G+ G PG+ G  G +G  GL GLPGPPG  G              G PG  GP G  G  
Sbjct: 1119 GEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGAN 1178

Query: 366  GVPGALGPRGEKGPIGAPGIGGPPGEPGL---PGIPGPMGPPGAIGFPGPKGEG 416
            G+PG +GP G +G  G  G  GPPG PG    PG PGP     A    GP+ +G
Sbjct: 1179 GIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG 1232



 Score =  218 bits (555), Expect = 2e-56
 Identities = 136/316 (43%), Positives = 152/316 (48%), Gaps = 47/316 (14%)

Query: 340 GLPGPPGLPGIGKPG----FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395
           G PGP G  G  +PG      GPKG  G  G  G  GPRG++G  G  G  GP G  G P
Sbjct: 98  GQPGPKGQKG--EPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155

Query: 396 GIPGPMGPPGAIGFPGPKGEGG---------------------IVGPQGPPGPKGEPGLQ 434
           G PG  GPPG  G PGP G GG                     + GP GP GP+G PG  
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 435 GFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQ 494
           G PG  GF G  G PG  G+ GP+GP+G  G  G PG  G  G  G  GE G PG QG +
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 275

Query: 495 GPPGIPGIGGPSGPIGPPGI---------PGPKGEPGLPGPPGFPG----IGKPGVAGLH 541
           G PG PG+ G  G  G PG+         PG KGE G PG  G PG     G PG  G  
Sbjct: 276 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT 335

Query: 542 GPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAY 601
           GP G  GA G  GQPG  GPPGP GP G P   P  P  +GE  P    G +G + P   
Sbjct: 336 GPAGAAGARGNDGQPGPAGPPGPVGPAGGPG-FPGAPGAKGEAGPTGARGPEGAQGP--- 391

Query: 602 GAKKGKNGGPAYEMPA 617
              +G+ G P    PA
Sbjct: 392 ---RGEPGTPGSPGPA 404



 Score =  211 bits (538), Expect = 2e-54
 Identities = 140/324 (43%), Positives = 158/324 (48%), Gaps = 66/324 (20%)

Query: 108  GKEIPLASLRGEQGP---RGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV--- 157
            GK+ P  + RG+ GP    GEPG +GP GPPG  G     G  G +G PGPQG  G    
Sbjct: 924  GKDGPKGA-RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI 982

Query: 158  ----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG- 206
                      G PG+PG  G+PG  G PGA G+ G  G +GP G+ GP G PG  G PG 
Sbjct: 983  VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGA 1042

Query: 207  ---------------------IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF 245
                                 +G PG PG PG PGP G  G +G  G  G +GP G  G 
Sbjct: 1043 DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSG- 1101

Query: 246  GMPGAPGVKGPPGMHGPPGPVGLPGV-------GKPGVTGFPGPQGPLGKPGAPGEPGPQ 298
               GA G++GP G  G  G  G PG        G  G+ G PGP GP G  GA G  GP 
Sbjct: 1102 -PAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS 1160

Query: 299  GPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKG---EQGLPGLPGPPGLPGIGKPGF 355
            GP G PG  GP G     K G +GIPG  G PG +G   E G  G PG PG P  G PG 
Sbjct: 1161 GPRGPPGPVGPSG-----KDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP--GPPGP 1213

Query: 356  PGPKGDRGMGGVPGALGPRGEKGP 379
            PGP  D  M    G LGPR EKGP
Sbjct: 1214 PGPGID--MSAFAG-LGPR-EKGP 1233


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  431 bits (1108), Expect = e-120
 Identities = 281/678 (41%), Positives = 319/678 (47%), Gaps = 123/678 (18%)

Query: 53  PLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIP 112
           P+G   P  P    G A G +    Q     P  P     + P    G    P    E  
Sbjct: 133 PMGPMGPRGPPGPAG-APGPQ--GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189

Query: 113 LASLRGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPGPQGYPGV-GKPGMPGMPG 167
                GE+GP G  G RG PG PGLPG     G PG+ G  G  G PGV G+ G PG  G
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249

Query: 168 KPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGLPGQPGPKGDRG 226
            PG MG  G  GE G+ G  G  G  G  G PGP G PG +G  GGPG PG PG KG+ G
Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 309

Query: 227 PKGLPGPQGLRGPKGDKGF-------------------------------GMPGAPGVKG 255
           P G  GP+G +GP+G+ G                                G PG PG +G
Sbjct: 310 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369

Query: 256 PPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG 314
           PPG  G  GP+G  G  G+PG+ GF G QGP G+PG  G  G  GP G  G +G  G PG
Sbjct: 370 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 429

Query: 315 ----IGKPGQDGIPGQPGFPGGKG---EQGLPGLPGPPGLPGI-------GKPGFPGPKG 360
               IG PG+ G PG  GFPG  G    +G PG  GP GL G        G+PG PG  G
Sbjct: 430 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 489

Query: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM---GPPGAIGFPGPKGEGG 417
            RG+ G PG  GP+G+ GP GAPG      E G PG PGP    G PG +GFPGPKG  G
Sbjct: 490 ARGLTGRPGDAGPQGKVGPSGAPG------EDGRPGPPGPQGARGQPGVMGFPGPKGANG 543

Query: 418 IVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPP------------------GMRGLPGPIG 459
             G  G  G  G PGL+G PGK G  G  GPP                  G +GLPGP G
Sbjct: 544 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG 603

Query: 460 PKGEAGQ---KGVPGLPGVPGLLGPKGEPGIPGD------QGLQGP---PGIPGIGGP-- 505
           P GE G+   +GVPG  G PGL+GP+GE G PG+      QGLQGP   PG PG  GP  
Sbjct: 604 PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 663

Query: 506 -SGPIGPPGIPGPKGEPGLPGPPGFPGI-------------------GKPGVAGLHGPPG 545
            SGP GPPG  GP G  G+PG  G  GI                   GK G  GL GP G
Sbjct: 664 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 723

Query: 546 KPGALGPQGQPGLPGPPGPP------GPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPH 599
            PG  G  G+ G  GPPGP       G PG      P P P G   P    G  G K   
Sbjct: 724 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP-PGPAGFAGPPGADGQPGAKGEQ 782

Query: 600 AYGAKKGKNGGPAYEMPA 617
               +KG  G P  + P+
Sbjct: 783 GEAGQKGDAGAPGPQGPS 800



 Score =  421 bits (1082), Expect = e-117
 Identities = 255/560 (45%), Positives = 286/560 (51%), Gaps = 66/560 (11%)

Query: 114  ASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGA 171
            A  +G+ GP G PG  G PGPPG  G  G PG+ G PGP+G  G  GK G  G+PG PG 
Sbjct: 500  AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 559

Query: 172  MGMPGAKGEIGQKGEIGP------------------MGIPGPQGPPGPHGLPGI-GKPGG 212
             G+PG  GE G  G  GP                   G+PGP GPPG  G PG  G PG 
Sbjct: 560  RGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGE 619

Query: 213  PGLPGQPGPKGDRG---PKGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPGMHGPPGP 265
             G PG  GP+G+RG    +G PG QGL+GP+G  G     G  GA G  GPPG  GPPG 
Sbjct: 620  AGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 679

Query: 266  VGLPG----------------VGKPGVTGFPG------------PQGPLGKPGAPGEPGP 297
             G+PG                VG+ G  G PG            P GP G  G  GE GP
Sbjct: 680  QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP 739

Query: 298  QGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGF---PGGKGEQGLPGLPGPPGLPGI-GK 352
             GP G  G +G PG  G  G PG  G  G PG    PG KGEQG  G  G  G PG  G 
Sbjct: 740  PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 799

Query: 353  PGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGP 412
             G PGP+G  G+ G  GA G +G  G  G PG  G  G PG  G PGP GPPG  G  GP
Sbjct: 800  SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGP 859

Query: 413  KGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGL 472
            KG  G     GPPG  GEPGLQG  G PG  GE G  G  G  GP GP+G AGQ+G+ GL
Sbjct: 860  KGARG---DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 916

Query: 473  PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG- 531
            PG  G  G  G PG  G+ G QG PG  G  GP GP+GPPG+ GP GEPG  G PG  G 
Sbjct: 917  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 976

Query: 532  IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLG 591
             G+ G AG+ G  G+ GA+G  G PG PG PGP GP G           QG   P    G
Sbjct: 977  PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA-GAQGPMGPSGPAG 1035

Query: 592  IDGVKPPHAYGAKKGKNGGP 611
              G++ P      KG+ G P
Sbjct: 1036 ARGIQGPQGPRGDKGEAGEP 1055



 Score =  421 bits (1081), Expect = e-117
 Identities = 252/544 (46%), Positives = 284/544 (52%), Gaps = 81/544 (14%)

Query: 100  GKEAVPKKGKEIPLASLRGEQG---PRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYP 155
            G + VP +     L   RGE+G    RG PG +G  GP GLPG  G  G KG  GP G P
Sbjct: 612  GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 671

Query: 156  GV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG---------PQGPPGPHGLP 205
            G  G PG+ GMPG+ GA G+ G KG+ G  GE GP G PG         P GPPGP G  
Sbjct: 672  GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 731

Query: 206  G----IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGP---------KGDKGF----GMP 248
            G    +G PG  G  G  G  G+RG  G PGP G  GP         KG++G     G  
Sbjct: 732  GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 791

Query: 249  GAPGVKGPPGMHGPPGPVGLPGV-------GKPGVTGFPGPQGPLGKPGAPGEPGPQGP- 300
            GAPG +GP G  GP GP G+ G        G PG TGFPG  G +G PG+ G PGP GP 
Sbjct: 792  GAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP 851

Query: 301  --------------------IGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLP 339
                                 G PG+QGP G PG  G+PG DG  G  G PG +G  G  
Sbjct: 852  GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 911

Query: 340  GLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP 398
            G+ G PG  G  G PG PGP G+ G  G PGA G RG  GP+G PG+ GP GEPG  G P
Sbjct: 912  GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 971

Query: 399  GPMGPP---GAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV--------- 446
            G  GPP   GA G  G +GE G VG  G PGP G PG  G  GK G  GE          
Sbjct: 972  GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS 1031

Query: 447  GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506
            GP G RG+ GP GP+G+ G+ G PG  G+ G  G  G  G+PG  G  G  G  G  GPS
Sbjct: 1032 GPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS 1091

Query: 507  GPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPG 566
            GP GPPG  GP G+ G  G PG   IG P      GP G+ G  GP G PG PGPPGPPG
Sbjct: 1092 GPRGPPGPVGPSGKDGANGIPG--PIGPP------GPRGRSGETGPAGPPGNPGPPGPPG 1143

Query: 567  PPGP 570
            PPGP
Sbjct: 1144 PPGP 1147



 Score =  418 bits (1075), Expect = e-117
 Identities = 274/621 (44%), Positives = 305/621 (49%), Gaps = 112/621 (18%)

Query: 94  QPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQ 152
           QP P+ G++  P   K+I         GP+G PGP+GP G  G  G  G  G KG PGP+
Sbjct: 30  QPGPK-GQKGEPGDIKDIV--------GPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPR 80

Query: 153 GYPG-VGKPGMPGMPGKPGAMGMPGAKGEI--------------GQKGEI-GPMGIPGPQ 196
           G  G  G PG PG PG PG  G PG  G                 Q G + GPMG  GP+
Sbjct: 81  GRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 140

Query: 197 GPPGPHGLPG----IGKPGGPGLPGQPGPKGDRGPKGLP---------------GPQGLR 237
           GPPGP G PG     G PG PG PG  GP G RGP G P               G +G  
Sbjct: 141 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 200

Query: 238 GPKGDKGF-GMPGAPGVKGP---PGMHGPPGPVGLPGV----GKPGVTGFPGPQGPLGKP 289
           GP+G +GF G PG PGVKG    PG+ G  G  G PGV    G PG  G PGP GP G P
Sbjct: 201 GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 260

Query: 290 GAPGEPGPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLP 348
           G  G  GP G  G  G  G PG  G  G  G  G PG PG PG KGE G  G  GP G  
Sbjct: 261 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 320

Query: 349 G----IGKPGFPGP---KGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPM 401
           G     G PG PGP    G+ G  G+PGA G  G  G  GAPG  GP G PG  G  GP+
Sbjct: 321 GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380

Query: 402 GPPGAIGFP---------GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMR 452
           GP G  G P         GPKGE G  GPQG PGP GE G +G  G+PG +G +GPPG R
Sbjct: 381 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440

Query: 453 GLPGPIGPKGE---AGQKGVPGLPGVPGLLGPK---GEPGIPGDQGLQGPPGI---PGIG 503
           G PG  G  G+   AG KG PG  G  GL GPK   G+PG PG+ GL G  G+   PG  
Sbjct: 441 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500

Query: 504 GPSGPIGPPGIPGPKGEPGLPGPP---------GFPG----IGKPGVAGLHGPPGKPGAL 550
           GP G +GP G PG  G PG PGP          GFPG     G+PG AG  G PG PG  
Sbjct: 501 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560

Query: 551 ---GPQGQPGLPGPPGPPGP---------PGPPAVM----PPTPPPQGEYLPDMGL---- 590
              G  G+ G  GPPGP GP         PGP        PP PP +G    D G+    
Sbjct: 561 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620

Query: 591 GIDGVKPPHAYGAKKGKNGGP 611
           G  G+  P       G+ G P
Sbjct: 621 GAPGLVGPRGERGFPGERGSP 641



 Score =  406 bits (1043), Expect = e-113
 Identities = 258/577 (44%), Positives = 278/577 (48%), Gaps = 104/577 (18%)

Query: 114  ASLRGEQGPRGEPGPRGPPGPPGLPGHG-IPGIKGKPGPQGYPGV----GKPGMPGMPGK 168
            A  RGEQG  G  G +G PGPPG PG G  PG +G PG  G PG+    G+ G PG  G 
Sbjct: 581  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 640

Query: 169  PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGP 227
            PGA G+ G +G  G  G  GP G  GP GPPG  G PG+ G PG  G  G  GPKGDRG 
Sbjct: 641  PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700

Query: 228  KGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPGMHGPPGPVGLPGV----------GK 273
             G  GP+G  G  G +G     G PG  G  G  G  GPPGP G  G           G 
Sbjct: 701  VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 760

Query: 274  PGVTGFPGPQGPLGKPGAPGE------------PGPQGPIGVPGVQGPPGIPGI-GKPGQ 320
            PG  GF GP G  G+PGA GE            PGPQGP G PG QGP G+ G  G  G 
Sbjct: 761  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 820

Query: 321  DGIPGQPGFPGGKGEQGLPGL---PGPPGLPG-------------------IGKPGFPGP 358
             G PG  GFPG  G  G PG    PGPPG PG                    G+PG  GP
Sbjct: 821  QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 880

Query: 359  KGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG---------EPGLPGIPGPMGPPGAIGF 409
             G  G  G PG  GP G +GP G  G+ G  G         E G PG+PGP G PG  G 
Sbjct: 881  AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 410  PGPKGEGGIVGPQGPPG---PKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ 466
            PG  G+ G  GP GPPG   P GEPG +G PG  G      PPG  G  G  G +GE G 
Sbjct: 941  PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG------PPGRDGAAGVKGDRGETGA 994

Query: 467  KGVPGLPGVPGLLGPKGEPGIPGD------QGLQGPPGIPGIGGPSGPIGPPGIPGPKGE 520
             G PG PG PG  GP G  G  GD      QG  GP G  G  G  GP GP G  G  GE
Sbjct: 995  VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE 1054

Query: 521  PG---------------LPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGP 564
            PG               LPGPPG  G  G  G AG  GP G PG +GP G+ G  G PGP
Sbjct: 1055 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP 1114

Query: 565  PGPPGP--------PAVMPPTPPPQGEYLPDMGLGID 593
             GPPGP        PA  P  P P G   P  G GID
Sbjct: 1115 IGPPGPRGRSGETGPAGPPGNPGPPGPPGPP-GPGID 1150



 Score =  248 bits (634), Expect = 1e-65
 Identities = 153/354 (43%), Positives = 170/354 (48%), Gaps = 55/354 (15%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV-------------GKP 160
            G  GP+G  G +GPPG  G PG     G PG  G PGP G PG              G P
Sbjct: 810  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869

Query: 161  GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQP 219
            G  G PG  G  G PG KGE G  G  G  G PGPQG  G  G+ G+ G+ G  G PG P
Sbjct: 870  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929

Query: 220  GPKGDRGPKGLPGPQGLRGPKGDKG----FGMPGAPGVKGPPGMHGPPGPVGLPGV---- 271
            GP G+ G +G PG  G RGP G  G     G  G PG +G PG  GPPG  G  GV    
Sbjct: 930  GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 989

Query: 272  ---------GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----GKP 318
                     G PG  G PGP GP GK G  GE G QGP+G  G  G  GI G     G  
Sbjct: 990  GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDK 1049

Query: 319  GQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-------------GKPGFPGPKGDRGMG 365
            G+ G PG+ G  G +G  GL GLPGPPG  G              G PG  GP G  G  
Sbjct: 1050 GEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGAN 1109

Query: 366  GVPGALGPRGEKGPIGAPGIGGPPGEPGL---PGIPGPMGPPGAIGFPGPKGEG 416
            G+PG +GP G +G  G  G  GPPG PG    PG PGP     A    GP+ +G
Sbjct: 1110 GIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG 1163



 Score =  216 bits (551), Expect = 5e-56
 Identities = 135/314 (42%), Positives = 151/314 (48%), Gaps = 47/314 (14%)

Query: 342 PGPPGLPGIGKPG----FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGI 397
           PGP G  G  +PG      GPKG  G  G  G  GPRG++G  G  G  GP G  G PG 
Sbjct: 31  PGPKGQKG--EPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 88

Query: 398 PGPMGPPGAIGFPGPKGEGG---------------------IVGPQGPPGPKGEPGLQGF 436
           PG  GPPG  G PGP G GG                     + GP GP GP+G PG  G 
Sbjct: 89  PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 148

Query: 437 PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGP 496
           PG  GF G  G PG  G+ GP+GP+G  G  G PG  G  G  G  GE G PG QG +G 
Sbjct: 149 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 208

Query: 497 PGIPGIGGPSGPIGPPGI---------PGPKGEPGLPGPPGFPG----IGKPGVAGLHGP 543
           PG PG+ G  G  G PG+         PG KGE G PG  G PG     G PG  G  GP
Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268

Query: 544 PGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGA 603
            G  GA G  GQPG  GPPGP GP G P   P  P  +GE  P    G +G + P     
Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGPAGGPG-FPGAPGAKGEAGPTGARGPEGAQGP----- 322

Query: 604 KKGKNGGPAYEMPA 617
            +G+ G P    PA
Sbjct: 323 -RGEPGTPGSPGPA 335



 Score =  211 bits (538), Expect = 2e-54
 Identities = 140/324 (43%), Positives = 158/324 (48%), Gaps = 66/324 (20%)

Query: 108  GKEIPLASLRGEQGP---RGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV--- 157
            GK+ P  + RG+ GP    GEPG +GP GPPG  G     G  G +G PGPQG  G    
Sbjct: 855  GKDGPKGA-RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI 913

Query: 158  ----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG- 206
                      G PG+PG  G+PG  G PGA G+ G  G +GP G+ GP G PG  G PG 
Sbjct: 914  VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGA 973

Query: 207  ---------------------IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF 245
                                 +G PG PG PG PGP G  G +G  G  G +GP G  G 
Sbjct: 974  DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSG- 1032

Query: 246  GMPGAPGVKGPPGMHGPPGPVGLPGV-------GKPGVTGFPGPQGPLGKPGAPGEPGPQ 298
               GA G++GP G  G  G  G PG        G  G+ G PGP GP G  GA G  GP 
Sbjct: 1033 -PAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS 1091

Query: 299  GPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKG---EQGLPGLPGPPGLPGIGKPGF 355
            GP G PG  GP G     K G +GIPG  G PG +G   E G  G PG PG P  G PG 
Sbjct: 1092 GPRGPPGPVGPSG-----KDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP--GPPGP 1144

Query: 356  PGPKGDRGMGGVPGALGPRGEKGP 379
            PGP  D  M    G LGPR EKGP
Sbjct: 1145 PGPGID--MSAFAG-LGPR-EKGP 1164



 Score =  145 bits (366), Expect = 1e-34
 Identities = 92/228 (40%), Positives = 104/228 (45%), Gaps = 37/228 (16%)

Query: 415 EGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPG 474
           +G  V   GP G KGEPG          +G  GPPG +G  G  GP+G+ G KG  G PG
Sbjct: 24  QGQDVRQPGPKGQKGEPG-----DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPG 78

Query: 475 VPGLLGPKGEPGIPGDQGLQGPPGIPGIG------------------------------G 504
             G  G  G PG PG  G  GPPG PG+G                              G
Sbjct: 79  PRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138

Query: 505 PSGPIGPPGIPGPKGEPGLPGPPGFPGIGKP-GVAGLHGPPGKPGALGPQGQPGLPGPPG 563
           P GP GP G PGP+G  G PG PG PG+  P G  G  GPPGKPG  G  G+PG  G  G
Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 198

Query: 564 PPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP 611
           PPGP G     P TP   G        G+DG K        KG++G P
Sbjct: 199 PPGPQGARG-FPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP 245


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  429 bits (1104), Expect = e-120
 Identities = 251/562 (44%), Positives = 281/562 (50%), Gaps = 85/562 (15%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV------------------ 157
           +G+ GPRG  GP GPPG  G+PG  G+PG  G PGP G PG+                  
Sbjct: 114 KGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTG 173

Query: 158 -----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG 206
                      G  G+PG PG PG  G  G  GE G+ G  GPMG  GP GPPG +G   
Sbjct: 174 GISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNG--D 231

Query: 207 IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF----------------GMPGA 250
            G+ G PG PG+ GP G +G +GLPG  GL G KG +GF                G PG+
Sbjct: 232 DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291

Query: 251 PGVKGPPGMHGP------------PGPVGLPG-VGKPGVTGFPGPQGPLGKPGAP----- 292
           PG  G PG  GP            PGP G  G  G  G  G PGP GP G PG P     
Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA 351

Query: 293 -GEPGPQGP---IGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGL 347
            GE GPQGP    G  GV+G PG PG  G  G  G PG  G PG KG  G PG+ G PG 
Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411

Query: 348 PGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAI 407
           PG       GP G +G GG PG  G  GE G  G+ G  G  GEPG  G+ GP GP G  
Sbjct: 412 PGA-----RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466

Query: 408 GFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQK 467
           G  G +GE G  G  GPPG +G PG +GFPG  G  G  GP G RG PGP GPKG  G+ 
Sbjct: 467 GKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEA 526

Query: 468 GVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527
           G PG  G+PG  G  G PG PG  G  GPPG  G  G  GP GPPG  G  G  G PGP 
Sbjct: 527 GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPK 586

Query: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPD 587
           G    G+PG AG  G PG PGA+GP G+ G  G  GPPGP GP          +GE  P 
Sbjct: 587 G--AAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAG-------ERGEQGPA 637

Query: 588 MGLGIDGVKPPHAYGAKKGKNG 609
              G  G+  P     + GK G
Sbjct: 638 GSPGFQGLPGPAGPPGEAGKPG 659



 Score =  425 bits (1092), Expect = e-119
 Identities = 251/565 (44%), Positives = 290/565 (51%), Gaps = 52/565 (9%)

Query: 117  RGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV----GKPGMPGMPGKPGA 171
            +G+ G +GEPGP G  GPPG  G  G  G +G+PGP G PG     G PG  G PG  G 
Sbjct: 442  KGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGV 501

Query: 172  MGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-------GKPGGPGLPGQPGPKGD 224
             G  G  GE G  G  GP G PG  G PG  GLPG        G PG  G  G PGP G 
Sbjct: 502  AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQ 561

Query: 225  RGPKGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGF 279
             G  G PGP G RG  G  GF    G  G PG  G  G+ GPPG VG  G  G+ G  G 
Sbjct: 562  DGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGP 621

Query: 280  PGP---------QGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGF 329
            PGP         QGP G PG  G PGP GP G  G  G  G+PG +G PG  G  G+ GF
Sbjct: 622  PGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681

Query: 330  PGGKGEQGLPGLPGPPGLPGI----------GKPGFPGPKGDRGMGGVPGALG------P 373
            PG +G QG PG  GP G  G           G PG PG +G  G+ G+PG  G      P
Sbjct: 682  PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741

Query: 374  RGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGL 433
            +G++G  G  G  G PG+ G+ G+ GP+GPPG  G PG KGE G  GP GP G +G PG 
Sbjct: 742  KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801

Query: 434  QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV------PGLLGPKGEPGI 487
            +G PG PG  G  GPPG  G PG  G  G+AG KG  G PG       PG +G  G PG 
Sbjct: 802  RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGA 861

Query: 488  PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKP 547
             G +G  GPPG  G  G +G +GPPG  G  G PG PGP G  G GK G  G  GP G+P
Sbjct: 862  KGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEG-GK-GPRGETGPAGRP 919

Query: 548  GALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGK 607
            G +GP G PG  G  G PG  GP A  P TP PQG       +G+ G +    +    G 
Sbjct: 920  GEVGPPGPPGPAGEKGSPGADGP-AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978

Query: 608  NGGPAYEMPAFTAELTAPFPPVGAP 632
            +G P  + P+  +    P  P+G P
Sbjct: 979  SGEPGKQGPSGASGERGPPGPMGPP 1003



 Score =  421 bits (1082), Expect = e-117
 Identities = 261/583 (44%), Positives = 291/583 (49%), Gaps = 86/583 (14%)

Query: 96   APRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQGY 154
            A + G++ VP        +  RGE+G  GE G +GPPGP G  G +G PG  G  G  G 
Sbjct: 655  AGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714

Query: 155  PGV----GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG---------PQGPPGP 201
            PG     G PG+ GMPG+ GA G+PG KG+ G  G  G  G PG         P GPPGP
Sbjct: 715  PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774

Query: 202  HGLPGI----------------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF 245
             G PG                 G PG  G PG PGP G  GP G  G  G +G  GD G 
Sbjct: 775  AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGA 834

Query: 246  -GMPGAPGVKGPPGMHGPPGPVGLPGV-------GKPGVTGFPG------PQGPLGKPGA 291
             G  G PG  GP G  GP G VG PG        G PG TGFPG      P GP G  G 
Sbjct: 835  KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP 894

Query: 292  PGEPGPQG------------PIGVPGVQGPPGIPGI----GKPGQDGIPGQPGFPGGKGE 335
            PG PGP G            P G PG  GPPG PG     G PG DG  G PG PG +G 
Sbjct: 895  PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954

Query: 336  QGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGL 394
             G  G+ G PG  G  G PG PGP G+ G  G  GA G RG  GP+G PG+ GPPGE G 
Sbjct: 955  AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGR 1014

Query: 395  PGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGL 454
             G PG  G PG  G PG KG+ G  GP GPPG  G       PG PG +G  G  G RG 
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA------PGAPGPVGPAGKSGDRGE 1068

Query: 455  PGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGI 514
             GP GP G  G  G  G  G  G  G KGE G  GD+G++G  G  G+ GP GP G PG 
Sbjct: 1069 TGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGE 1128

Query: 515  PGPKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV 573
             GP G  G  GP G PG  G PG  GL+G PG  G  GP+G+ G  GP GPPGPPGPP  
Sbjct: 1129 QGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG- 1187

Query: 574  MPPTPPPQG---EYLPDMGLGIDGVKPPHAYGAKKGKNGGPAY 613
             PP PP  G    +LP         +PP     +K  +GG  Y
Sbjct: 1188 -PPGPPSAGFDFSFLP---------QPPQ----EKAHDGGRYY 1216



 Score =  412 bits (1060), Expect = e-115
 Identities = 256/591 (43%), Positives = 287/591 (48%), Gaps = 86/591 (14%)

Query: 117 RGEQGPRGEPG---------PRGPPGPPGLPGH-------GIPGIKGKPGPQGYPGV-GK 159
           +G QGP GEPG         PRGPPGPPG  G        G PG +G PGPQG  G+ G 
Sbjct: 199 QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGT 258

Query: 160 PGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPG---PHGLPGIGKPGGPGLP 216
            G+PGM G  G  G+ GAKG+ G  G  G  G PG  G PG   P GLPG  + G PG P
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG--ERGRPGAP 316

Query: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV-GKPG 275
           G  G +G+ G  G  GP G  GP G  GF  PGA G KG  G  GP G  G  GV G+PG
Sbjct: 317 GPAGARGNDGATGAAGPPGPTGPAGPPGF--PGAVGAKGEAGPQGPRGSEGPQGVRGEPG 374

Query: 276 VTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----------GKPGQDGIPG 325
             G  G  GP G PGA G+PG +G  G PG+ G PG PG           G PG  G  G
Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434

Query: 326 QPGFPGGKGEQGLPGLPGPPGLPGI----------------GKPGFPGPKGDRG------ 363
           +PG PG KG+ G  G PGP G+ G                 G  G PGP G+RG      
Sbjct: 435 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRG 494

Query: 364 ---MGGVPGALGPRGEKG------PIGAPGIGGPPGEPGLPGI------PGPMGPPGAIG 408
                GV G  GP GE+G      P G+PG  G PGE GLPG       PG  GP G  G
Sbjct: 495 FPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG 554

Query: 409 FPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG 468
            PGP G+ G  GP GPPG +G+ G+ GFPG  G  GE G  G RG+PGP G  G AG+ G
Sbjct: 555 PPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDG 614

Query: 469 VPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG 528
             G  G PG  GP GE      +G QGP G PG  G  GP GPPG  G  GE G+PG  G
Sbjct: 615 EAGAQGPPGPAGPAGE------RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLG 668

Query: 529 FPG-------IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQ 581
            PG        G PG  G+ GPPG  G  G  G PG  G  G  G PG P      P  Q
Sbjct: 669 APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPG-SQGAPGLQ 727

Query: 582 GEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
           G        G+ G K        KG +G P  +          P  P GAP
Sbjct: 728 GMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778



 Score =  266 bits (681), Expect = 4e-71
 Identities = 178/450 (39%), Positives = 195/450 (43%), Gaps = 107/450 (23%)

Query: 251 PGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQG---PLGKPGAPGEPGPQGPIGVPGVQ 307
           PG + P G   P  P G         TG  GP+G   P G  G  G PG  G  G PG+ 
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 308 GPPGIPG--------------------------------IGKPGQDGIPGQPGFPGGKGE 335
           GPPG PG                                +G  G  G+PG PG PG +G 
Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201

Query: 336 QGLPGLP------------GPPGLPG-------IGKP---------------------GF 355
           QG PG P            GPPG PG        GKP                     G 
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261

Query: 356 PGPKGDRGMGGVPGA---LGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGP 412
           PG KG RG  G+ GA    GP G KG  G+PG  G PG+ G  G+PG  G PGA G  G 
Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321

Query: 413 KGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV---------GPPGMRGLPGPIGPKGE 463
           +G  G  G  GPPGP G  G  GFPG  G  GE          GP G+RG PGP GP G 
Sbjct: 322 RGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA 381

Query: 464 AGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGL 523
           AG  G PG  G PG  G  G PGI       G PG PG  GPSGP GP G PGPKG  G 
Sbjct: 382 AGPAGNPGADGQPGAKGANGAPGI------AGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435

Query: 524 PGPPGFPG----IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP 579
           PG PG  G     G+PG  G+ GPPG  G  G +G  G PGP G PGPPG          
Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG------G 489

Query: 580 PQGEYLPDMGLGIDGVKPPHAYGAKKGKNG 609
           P     P    G DGV  P     ++G  G
Sbjct: 490 PGSRGFP----GADGVAGPKGPAGERGSPG 515



 Score =  109 bits (273), Expect = 8e-24
 Identities = 71/177 (40%), Positives = 80/177 (45%), Gaps = 12/177 (6%)

Query: 92   EIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKG 147
            E  PA   G    P     +  A   G++G  G  GP GP GP G  G     G  G KG
Sbjct: 1038 ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKG 1097

Query: 148  KPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG 206
            + G QG  G+ G  G  G+ G PG  G PG +G  G  G  GP G PG  G PG  GL G
Sbjct: 1098 ETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNG 1157

Query: 207  IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFG-----MPGAPGVKGPPG 258
            +  P GP  PG  G  GD GP G PGP G  GP G    G     +P  P  K   G
Sbjct: 1158 LPGPIGP--PGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDG 1212



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 49/129 (37%), Positives = 57/129 (44%), Gaps = 24/129 (18%)

Query: 500 PGIGGPSG---PIGPPGIPGPKGEP--GLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQG 554
           PG   P G   P+ P G   P  +   G+ GP G       G  G  GP G PG  G  G
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKG-----DTGPRGPRGPAGPPGRDGIPG 136

Query: 555 QPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGID-----GVKPPHAYG--AKKGK 607
           QPGLPGPPGPPGPPGPP +        G + P +  G D     G+  P   G    +G 
Sbjct: 137 QPGLPGPPGPPGPPGPPGL-------GGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGL 189

Query: 608 NGGPAYEMP 616
            G P    P
Sbjct: 190 PGPPGAPGP 198


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  427 bits (1099), Expect = e-119
 Identities = 263/610 (43%), Positives = 301/610 (49%), Gaps = 130/610 (21%)

Query: 84   PHLPQYMKEIQPAPRMGKEAVPKKGKEIP-LASLRGEQGPRGEPGPRGPPGPPGLPG--- 139
            P LP       P PRM  E  PK  K  P L    G QG  GE GP+GP GPPG  G   
Sbjct: 848  PGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEG 907

Query: 140  -HGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG 197
             HG PG  G PG  G+ G  G  G PG  G PG  G PG  GE G+KG  G  G PGP G
Sbjct: 908  AHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVG 967

Query: 198  PPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGP-----------------K 240
            P G  G PG+  P G G  G+PG    RG  GLPGP G +                   K
Sbjct: 968  PRGDPGAPGLPGPPGKGKDGEPGL---RGSPGLPGPLGTKAACGKVRGSENCALGGQCVK 1024

Query: 241  GDKGF-GMPGAPGVKGPPGMH--GPPGPVGLPG----VGKPGVTGFPGPQGPLGKPGAPG 293
            GD+G  G+PG+PG +G PG+   GPPGP G PG     G  G+ GFPGPQGP G+ GAPG
Sbjct: 1025 GDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPG 1084

Query: 294  EPGPQGPIGVPGVQ---------------------GPPGIPGI-GKPGQDGIPGQPG--- 328
             PG +GP G PG+                      GPPG+PG+ G  G  G+PG+PG   
Sbjct: 1085 NPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREG 1144

Query: 329  FPGGKGEQGLPGLPGPPGLPG----------------------------IGKPGFPGPKG 360
              G KGE G PGLPGPPG+ G                            +G PG PGP G
Sbjct: 1145 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG 1204

Query: 361  DRGMGGV---------PGALGPRGEKGPIGAPGIGG------------PPGEPGL---PG 396
              G+ G          PG  GP G +GP G PGI G            PPGEPG    PG
Sbjct: 1205 ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 1264

Query: 397  IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGP-------- 448
            +PGP G  G  GF G  G+ G  GP+G  G  G PG +G PGK G  G  GP        
Sbjct: 1265 LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRG 1324

Query: 449  -------PGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG 501
                   PG  G PGP G  G+ G KG  G PG+PG LGP+G PG PG++G+ G  G+PG
Sbjct: 1325 PPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG 1384

Query: 502  IGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGP 561
              G  G  G  G PG KG+ G PG     G G+PG  G+ G  G  G +GPQG PG  GP
Sbjct: 1385 KPGEPGFKGERGDPGIKGDKGPPG-----GKGQPGDPGIPGHKGHTGLMGPQGLPGENGP 1439

Query: 562  PGPPGPPGPP 571
             GPPGPPG P
Sbjct: 1440 VGPPGPPGQP 1449



 Score =  415 bits (1067), Expect = e-116
 Identities = 299/767 (38%), Positives = 343/767 (44%), Gaps = 190/767 (24%)

Query: 37   PPQIPPQMPP-----QIPQYQPLGQQVPHMPLAKDGLA--MGKEMPHLQYGKEYPHLPQY 89
            PP  PPQ PP     QI   + +    P     + G+A  MG   P    G   P     
Sbjct: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511

Query: 90   MKEIQPAPRMGKEAVPKKGKEIPLA-----------SLRGEQGPRGEP------GPRGPP 132
             K  +    +G     +KG++  L             +RGE G  GEP      G RGP 
Sbjct: 512  PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQ 571

Query: 133  GPPGLPGH----GIPGIKGKPGPQGYPG----------VGKPGMPGMPGKPGAMGMPGAK 178
            GPPGLPG     G PG++G+ G +G  G           GKPG  G  G+PG  G+ G +
Sbjct: 572  GPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQ 631

Query: 179  GEIGQKGEIGPMGIPG----PQGPPGPHGLPG-IGKPGGPGLPGQPGPKGDRGPKGLPGP 233
            GE G  G  GP G+PG     +G  G  G PG  G  G PG PG  GP G  G  G PG 
Sbjct: 632  GEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGL 691

Query: 234  QGLRGPKGDKGFGMPGAPGV------KGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLG 287
            QGLRG KGD   G PG PG+       GPPG+ GPPGP G PG+  PG  GFPG  GP G
Sbjct: 692  QGLRGKKGD--MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGL--PGEIGFPGKPGPPG 747

Query: 288  KPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGL--------- 338
              G PG+ GP GP G PG +G P     G+ G+DG+PG+PG  G  GEQGL         
Sbjct: 748  PTGPPGKDGPNGPPGPPGTKGEP-----GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGE 802

Query: 339  PGLPGPPGLPGI----------GKPGFPGPKGDRGMGGVPGALGP--------------- 373
             GLPG PG PG+          G+ G PG KGDRG  G  G  GP               
Sbjct: 803  AGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR 862

Query: 374  -RGEKGPIGAPGIGGPPGEPGLPGIPGPMGP------------------PGAIGFPGPKG 414
              GE+GP G  G  G PGEPGL G PG +GP                  PGA G PG  G
Sbjct: 863  MPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPG 922

Query: 415  EGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP- 473
              G  GP GPPG  G PGL+G PGK G  GE G  G  G PGP+GP+G+ G  G+PG P 
Sbjct: 923  HVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG 982

Query: 474  ----------GVPGLLGP--------------------------KGEPGIPGDQGLQGPP 497
                      G PGL GP                          +G PGIPG  G +G P
Sbjct: 983  KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDP 1042

Query: 498  GIPGIGGPSGPIGPP---GIPGPKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGAL--- 550
            GI G+ GP GP GPP   G PG +G PG PGP G  G  G PG  G  GPPGKPG     
Sbjct: 1043 GI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLL 1101

Query: 551  ------------------GPQGQPGLPGPPGPPGPPGPP-----------AVMPPTPPPQ 581
                              GP G PGLPG  G  G PG P           A  P  P P 
Sbjct: 1102 SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP 1161

Query: 582  GEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPP 628
            G   P    G  G +       +KG  G P   +P F      P PP
Sbjct: 1162 GIAGPQ---GSQGERGADGEVGQKGDQGHPG--VPGFMGPPGNPGPP 1203



 Score =  414 bits (1064), Expect = e-115
 Identities = 265/614 (43%), Positives = 293/614 (47%), Gaps = 142/614 (23%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGE--QGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQ 152
            P P +G +A   K +     +L G+  +G RG PG  G PG  G PG G+ G    PGP 
Sbjct: 998  PGP-LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAG---PPGPS 1053

Query: 153  GYPG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG----------------- 194
            G PG  G PG  G+PG PG  G  G  G  G  GE GP G PG                 
Sbjct: 1054 GPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDV 1113

Query: 195  ----PQGPPGPHGLPGI----GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF- 245
                P GPPG  GLPG     G PG PG  G  G KG+ GP GLPGP G+ GP+G +G  
Sbjct: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173

Query: 246  ------------GMPGAPGVKGPPGMHGPPGPVGLPGV-------GKPGVTGFPGPQGPL 286
                        G PG PG  GPPG  GPPG  G+ G        G PG  G PGPQGP 
Sbjct: 1174 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233

Query: 287  GKPGAPGEPGPQG------PIGVPGVQGPPGIPGI----GKPGQDGIPGQPGFPGGKGEQ 336
            G PG PGE G +G      P G PG  G PG+PG     G PG  G  G  G PG +GE 
Sbjct: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293

Query: 337  GLPGLPGPPGLPGI-------------------GKPGFPGPKGDRGMGGVPGALGPRGEK 377
            G  GLPG  GLPG                    GK G PG  G+ G  G PG  G +GE 
Sbjct: 1294 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGEN 1353

Query: 378  GPIGAPGI---GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGG---IVGPQGPPGPKGEP 431
            G  G PG     GPPGEPG  G+PG  G PG  G PG KGE G   I G +GPPG KG+P
Sbjct: 1354 GSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQP 1413

Query: 432  GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV---------------- 475
            G  G PG  G  G +GP G+ G  GP+GP G  GQ G PGL G                 
Sbjct: 1414 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELG 1473

Query: 476  -------------------------PGLLGPKGEPGIPGDQGLQGPPGIPGIGG---PSG 507
                                     PG  GP G+ G+PG  G  G PG PG GG   PSG
Sbjct: 1474 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 1533

Query: 508  PIGPPGIPGPKGEPGLP--------GPPGFPG-IGKPGVA--GLHGPPGKPGALGPQGQP 556
            PIGP G  G KG+PG P        GPPG PG  G+PG A  GL G PG  G  GP G P
Sbjct: 1534 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHP 1593

Query: 557  GLPGPPGPPGPPGP 570
            GLPGPPGPPG   P
Sbjct: 1594 GLPGPPGPPGQCDP 1607



 Score =  395 bits (1016), Expect = e-110
 Identities = 256/575 (44%), Positives = 292/575 (50%), Gaps = 70/575 (12%)

Query: 94   QPAPRMGKEAVPKKGKE-------IPLASLRGEQGPRGEPGPRGPPGPPGLPGH----GI 142
            +P P    +  P  G E       I  +   GE+G  G  GP G PGP G  G     G 
Sbjct: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGA 509

Query: 143  PGIKGKPGP-------QGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG 194
            PG KG+ G        QG  G  G  G+PG PG+ G+ GM G  GE+G+ G  G +G+ G
Sbjct: 510  PGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRG 569

Query: 195  PQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGV 253
            PQGPPG  G PG  + G PGL G+ G KG RG KG  G  G  G  GD G  G PG  GV
Sbjct: 570  PQGPPGLPGPPG--RVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGV 627

Query: 254  KGPPGMHGPPGPVGLPGVG-----KPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQG 308
             GP G  G  GP G PGV      + G+ G  G  GP G  GAPG PG +GPIG  G  G
Sbjct: 628  AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG 687

Query: 309  PPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367
            PPG+ G+ GK G  G PG PG  G +G  G PG+PGPPG PG G PG PG  G  G  G 
Sbjct: 688  PPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG-PG-GSPGLPGEIGFPGKPGP 745

Query: 368  PGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGP 427
            PG  GP G+ GP       GPPG PG  G PG  G  G  G PG +GE G  G  G PG 
Sbjct: 746  PGPTGPPGKDGP------NGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE 799

Query: 428  KGEPGLQGFPGKPGFLGEVGPPGMRG------LPGPIGPKGEAGQKGVPGLPG------- 474
            KGE GL G PG PG  GE G  G +G      L G  G KGEAG  G PGLPG       
Sbjct: 800  KGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTP 859

Query: 475  ---VPGLLGPKGE---PGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG 528
               +PG  GPKGE   PG+PG+ GLQG PG  G  GP+GP G  G  G  G PG  G PG
Sbjct: 860  HPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG 919

Query: 529  FPG-------------IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575
             PG             +G PG+ G  G  G+ G  G  G+ G PGP GP G PG P +  
Sbjct: 920  APGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGL-- 977

Query: 576  PTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGG 610
            P PP +G+       G  G+  P    A  GK  G
Sbjct: 978  PGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRG 1012



 Score =  392 bits (1006), Expect = e-109
 Identities = 259/670 (38%), Positives = 291/670 (43%), Gaps = 179/670 (26%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-------------------- 139
            G    P K  E       GE+G  G  GPRG PG PGLPG                    
Sbjct: 940  GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 999

Query: 140  ---------------------------HGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAM 172
                                        G PGI G PG +G PG+G  G PG  G PG  
Sbjct: 1000 PLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDK 1059

Query: 173  GMPGAKGEIGQKGEIGPMG---IPGPQGPPGPHGLPGIGK-------------------P 210
            G PG++G  G  G  GP G    PG  G  GP G PG+                     P
Sbjct: 1060 GSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPP 1119

Query: 211  GGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLP 269
            G PGLPG PG KGD+G  G PG +G  G KG+ G  G+PG PG+ GP G  G  G  G  
Sbjct: 1120 GPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEV 1179

Query: 270  GV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPG 328
            G  G  G  G PG  GP G PG PG  G  G  G PG+QG PG  G   PG  G  G PG
Sbjct: 1180 GQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEG--PPGPQGPSGLPG 1237

Query: 329  FPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPG------ALGPRGEKGPIG 381
             PG +G++G  G PGPPG PG  G+PG PGP+G RG  G  G      A GPRGE G +G
Sbjct: 1238 IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMG 1297

Query: 382  APGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG---PQGPPGPKGEPGLQGFPG 438
             PG  G PG+ G  G  GP GP G  G PG  G  G  G   P G PG KG  G  G PG
Sbjct: 1298 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 1357

Query: 439  KPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGI------PGDQG 492
             PGFLG  GP      PG  G KG  G++GVPG PG PG  G +G+PGI      PG +G
Sbjct: 1358 LPGFLGPRGP------PGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 1411

Query: 493  LQGPPGIPGIGGPSGPIGPPGIP---GPKGEPGLPGPPGFPGI----------------- 532
              G PGIPG  G +G +GP G+P   GP G PG PG PGFPG+                 
Sbjct: 1412 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471

Query: 533  -------------------------GKPGVAGLHGPPGKPGALGPQGQPGLP-------- 559
                                     G+PG  G  G  G PG  GP G+PG P        
Sbjct: 1472 LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGP 1531

Query: 560  ---------------------------GPPGPPGPPGPPAV----MPPTPPPQGEYLPDM 588
                                       GPPG PG PG P      +P  P PQGE  P  
Sbjct: 1532 SGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAG 1591

Query: 589  GLGIDGVKPP 598
              G+ G   P
Sbjct: 1592 HPGLPGPPGP 1601



 Score =  347 bits (890), Expect = 2e-95
 Identities = 229/537 (42%), Positives = 266/537 (49%), Gaps = 89/537 (16%)

Query: 150 GPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIG---------QKGEIGPMGIPGPQGPPG 200
           GP     V +P  P  P +P     PG++ +IG           GE G MG+ GP G PG
Sbjct: 441 GPCQVTVVTEPPPPPPPQRPPT---PGSE-QIGFLKTINCSCPAGEKGEMGVAGPMGLPG 496

Query: 201 PHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGM 259
           P G       G  G  G PGPKG++G  G+ GP G +G KG+KG  G+PG PG  G  GM
Sbjct: 497 PKG-----DIGAIGPVGAPGPKGEKGDVGI-GPFG-QGEKGEKGSLGLPGPPGRDGSKGM 549

Query: 260 HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGE---PGPQGPIGVPGVQGPPGIPGI- 315
            G PG +G PG+  PG  G  GPQGP G PG PG    PG QG  G  G +G  G  G+ 
Sbjct: 550 RGEPGELGEPGL--PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLD 607

Query: 316 ---GKPG---QDGIPGQPGFPGGKGEQGLPGLPGPPGLPG--IGKPGFPGPKGDRGMGGV 367
              GKPG   Q G PG  G  G +GE+G  G  GPPG+PG  + + G  G +G  G  G 
Sbjct: 608 GFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGH 667

Query: 368 PGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGA---IGFPGPKGEGGIVGPQGP 424
            GA GP G +GPIG  G  GPPG  GL G  G MGPPG    +G  GP G  G+ GP GP
Sbjct: 668 QGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP 727

Query: 425 PGPKGEPGLQGFPGKPGFLGEVGPPGM---RGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481
            G  G PG  GFPGKPG  G  GPPG     G PGP G KGE G++G  GLPG PGL G 
Sbjct: 728 GGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGE 787

Query: 482 KGE------PGIPGDQGLQGPPGIPGI------------------------GGPSGPIGP 511
            GE      PG  G+ GL G PG PG+                         G +GP GP
Sbjct: 788 IGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGP 847

Query: 512 PGIP----------------GPKGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQG 554
           PG+P                GPKGE G PG PG PG+ G+PG  G  GP G PGA G +G
Sbjct: 848 PGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEG 907

Query: 555 QPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP 611
             G PG  G PG PG      P+ PP     P +  G  G           G+ G P
Sbjct: 908 AHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGL-RGTPGKDGERGEKGAAGEEGSP 963



 Score =  166 bits (421), Expect = 6e-41
 Identities = 117/295 (39%), Positives = 139/295 (47%), Gaps = 52/295 (17%)

Query: 53   PLGQQVPHMPLAKDGL--AMGKEMPHLQYGKE-------YPHLPQYMKEIQPAPRMG--- 100
            P G Q P  P  K+G   + G+  P    G++        P LP ++    P    G   
Sbjct: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKG 1375

Query: 101  ---KEAVPKKGKEIPLASLRGEQGPRGEPGP---RGPPGPPGLPGHGIPGIKGKPGPQGY 154
               KE VP K  E      RG+ G +G+ GP   +G PG PG+PGH   G  G  GPQG 
Sbjct: 1376 VPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGH--KGHTGLMGPQGL 1433

Query: 155  PG----VGKPGMPGMPGKPGAMGMPGA--------KGEIGQKGEI--------------- 187
            PG    VG PG PG PG PG  G   +        + E+G++ E                
Sbjct: 1434 PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMK 1493

Query: 188  GPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGM 247
               G PGP GPPG  GLPG  + G  G PG+PG  G  GP G  GP+G RG KGD G   
Sbjct: 1494 SSQGRPGPPGPPGKDGLPG--RAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG 1551

Query: 248  PGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302
             G  G  GPPG+ G PG    PG  K G+ G PGPQG  G  G PG PGP GP G
Sbjct: 1552 VGLRGEMGPPGIPGQPGE---PGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  426 bits (1096), Expect = e-119
 Identities = 270/635 (42%), Positives = 297/635 (46%), Gaps = 132/635 (20%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIP-GIKGKPGPQGYPGVG 158
            G   +P    E      RG  GP G PG +GP G  G PG   P G  G+PG  G P  G
Sbjct: 474  GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP--G 531

Query: 159  KPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPG 217
             PGM GMPG PG    PG+ G+ G  G  G  G PGP GP GP G PG+ G PG  G  G
Sbjct: 532  GPGMRGMPGSPGG---PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG 588

Query: 218  QPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGV----G 272
             PG  G+RG  G PGPQG  G  G+ G  G PG  G  G  G  GPPGP GL G+    G
Sbjct: 589  APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG 648

Query: 273  KPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGG 332
             PG  G PG  GP G  GAPG PG +G  G PG +GPPG+   G PG  G  G PG  GG
Sbjct: 649  PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL--AGAPGLRGGAGPPGPEGG 706

Query: 333  KGEQGLPGLPGPPGLPGI-------GKPGFPGPKGDR------GMGGVPGALGPRGEKGP 379
            KG  G PG PG  G PG+       G  G PGPKGD+      G  GVPG  GPRG  GP
Sbjct: 707  KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGP 766

Query: 380  IGAPGIGGPPGE------PGLPGIPGP---------MGPPGAIGF--------------- 409
            IG PG  G PG+      PGLPGI GP          GPPG  GF               
Sbjct: 767  IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGE 826

Query: 410  ---PGPKGEGGI---------VGPQGPPGPKGE---------------PGLQGFPGKPGF 442
               PG KGEGG           GP GPPGP+G                PG +G PG PG 
Sbjct: 827  RGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGS 886

Query: 443  LGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIP-- 500
             G  GPPG  G PG  GP G AG  G PG PGV G  G  G+PG  G  G QGPPG P  
Sbjct: 887  NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGP 946

Query: 501  ----GIGGPSGPIGPPGIPGPKGEP---------------------GLPGPPGFPGI--- 532
                GI G  G  GPPG+PGP+G P                     G PGP G PG+   
Sbjct: 947  LGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT 1006

Query: 533  -------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPT-------- 577
                   G PG  GL G  G PG  G +G+ G PG PG PG PGPP  + P         
Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE 1066

Query: 578  ---PPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNG 609
                 P G   P    G  G + P     + G+ G
Sbjct: 1067 SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG 1101



 Score =  426 bits (1095), Expect = e-119
 Identities = 265/621 (42%), Positives = 301/621 (48%), Gaps = 92/621 (14%)

Query: 95  PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPG 150
           P P MG    P +     L    G +G  G  G  G PGPPG PG     G PG KG+ G
Sbjct: 296 PGP-MGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVG 354

Query: 151 PQGYPGV-------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIP---------G 194
           P G PG        G+PG  G  G  G  G PG  G  G KGE+GP GIP         G
Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414

Query: 195 PQGPPGPHGLPGI----GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF----- 245
           P GP G +G PG+    G+PG  G  G+PGP+G+RG  G+PG  G +G  G  G      
Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPG 474

Query: 246 --GMPGAPGVKGPPGMHGPPGPVGLPG-------------------VGKPGVTGFPGPQG 284
             G+PGA G +G PG  GP GP G+PG                    G+PG  G PG  G
Sbjct: 475 ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPG 534

Query: 285 PLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-------IGKPGQDGIP---GQPGFPGGKG 334
             G PG+PG PG  G  G PG QG  G PG        G+PG  G P   G  G PG  G
Sbjct: 535 MRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594

Query: 335 EQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG 393
           E+G PG PGP G PG  G+ G  GP G  G GG  G  GP G +G  G PG GGPPGE G
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG 654

Query: 394 LPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRG 453
            PG PGP G  GA G PG KG+ G  G +GPPG  G PGL+G  G P      GP G +G
Sbjct: 655 KPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP------GPEGGKG 708

Query: 454 LPGPIGPKGEAGQKGVPGLPGVPGLL---GPKGEPGIPGDQGLQGPPGIPGIGGPSGPIG 510
             GP GP G AG  G+ G+PG  G L   GPKG+ G PG  G  G PG  G  GP+GPIG
Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 511 PPGIPGPKGEPGLPGPPGFPGI----GKPGVAGLHGPP------------GKPGALGPQG 554
           PPG  G  G+ G  G PG PGI    G PG  G  GPP            G+PG  G +G
Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828

Query: 555 QPGLPGPPGPPGPPGPPAVMPPTPPP-----QGEYLPDMGLGIDGVKPPHAYGAKKGKNG 609
            PG  G  GPPG  GPP    P  PP     +GE     G G  G           G NG
Sbjct: 829 APGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNG 888

Query: 610 GPAYEMPAFTAELTAPFPPVG 630
            P    P+ +     P  P G
Sbjct: 889 NPGPPGPSGSPGKDGPPGPAG 909



 Score =  422 bits (1084), Expect = e-118
 Identities = 268/624 (42%), Positives = 297/624 (47%), Gaps = 116/624 (18%)

Query: 83  YPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGP------------RGEPGPRG 130
           +P  P    E+ PA   G    P +  E       G QGP            +GE GP G
Sbjct: 343 FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAG 402

Query: 131 PPGPPGLPG----------HGIPGI------------KGKPGPQ------GYPGV----G 158
            PG PGL G          +G PG+            KG+PGP+      G PGV    G
Sbjct: 403 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG 462

Query: 159 KPGMPGMPGKPGAMGMPGAKGEIGQ---KGEIGPMGIPGPQGPPGPHGLPG--------- 206
           + G  G PG+PGA G+PGA GE G    +G  GP GIPG +GP G  G PG         
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG 522

Query: 207 ----------------IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF----- 245
                            G PGGPG  G+PGP G +G  G PGP G  GP+G  G      
Sbjct: 523 EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG 582

Query: 246 --GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302
             G  GAPG  G  G  G PGP G PG  G+ G  G PGP GP G  G  G PGPQG  G
Sbjct: 583 PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQG 642

Query: 303 VPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGD 361
           +PG  GPPG  G  G+PG  G  G PG PGGKG+ G PG  GPPGL   G PG  G  G 
Sbjct: 643 LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL--AGAPGLRGGAGP 700

Query: 362 RGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP------PGAIGFPGPKGE 415
            G  G  GA GP G  G  G PG+ G PGE G  G PGP G       PGA G PG  G 
Sbjct: 701 PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGP 760

Query: 416 GGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV 475
            G  GP GPPGP G+PG +G  G PG  G  GP   RG PG  G  G  G  G PG PG 
Sbjct: 761 RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGP---RGSPGERGETGPPGPAGFPGAPGQ 817

Query: 476 PGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKP 535
            G  G KGE G PG++G  GPPG+ G  G SGP GPPG  G KGE G PG PG  G   P
Sbjct: 818 NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGF--P 875

Query: 536 GVAGLHGPP---GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGI 592
           G  GL GPP   G PG  GP G PG  GPPGP G  G P                   G 
Sbjct: 876 GARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP-------------------GS 916

Query: 593 DGVKPPHAYGAKKGKNGGPAYEMP 616
            GV  P     + G+ G P  + P
Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGP 940



 Score =  420 bits (1080), Expect = e-117
 Identities = 272/625 (43%), Positives = 308/625 (49%), Gaps = 99/625 (15%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGP---RGEPGPRGPPGPPGLPGHGIPGIKGKPGP 151
            P P+ G +  P K  E       G QGP    GE GP+GPPGP G PG G  G  G PGP
Sbjct: 581  PGPK-GNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG-PG-GDKGDTGPPGP 637

Query: 152  QGYPGV----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG---- 197
            QG  G+          GKPG PG  G  GA G PG KG+ G  GE GP G+ G  G    
Sbjct: 638  QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697

Query: 198  --PPGPHGLPGI----GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGA 250
              PPGP G  G     G PG  G PG  G  G+RG  G PGP+G +G  G  G  G+PG 
Sbjct: 698  AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757

Query: 251  PGVKGPPGMHGPPGPVG------------LPGV----GKPGVTGFPGPQGPLGKPGAPGE 294
             G +GP G  GPPGP G            LPG+    G PG  G  GP GP G PGAPG+
Sbjct: 758  DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQ 817

Query: 295  ------------PGPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGL 341
                        PG +G  G PGV GPPG  G  G PG  G+ G+ G PGG G  G PG 
Sbjct: 818  NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA 877

Query: 342  PGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGP------PGEPGL 394
             G PG PG  G PG PGP G  G  G PG   P G  G  G+PG+ GP      PGE G 
Sbjct: 878  RGLPGPPGSNGNPGPPGPSGSPGKDGPPG---PAGNTGAPGSPGVSGPKGDAGQPGEKGS 934

Query: 395  PGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGF------PGKPGFLGEVGP 448
            PG  GP G PG +G  G  G  G+ GP G PGP+G PG QG       PG  G  GE GP
Sbjct: 935  PGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP 994

Query: 449  PGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGP 508
            PG +GLPG  G  GE G+ G PG  G+PG  G  G  G  G+ G  G PG PG  GP GP
Sbjct: 995  PGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP 1054

Query: 509  IGPPGIPGPKGEPGLPGPPGFPG-IGKPGVAGLHGP------PGKPGALGPQGQPGLPGP 561
            +GP G  G +GE G  GP G PG  G  G  G  GP       G+ GA G +G  G PG 
Sbjct: 1055 VGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGN 1114

Query: 562  PGPPGPPGPP----AVMPPTPP-PQGEYLPDMGLGIDG-------VKPPHAYG--AKKGK 607
            PG PG PGP     A+  P P  P+G   P    G DG       + PP   G   ++G 
Sbjct: 1115 PGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGS 1174

Query: 608  NGGPAYEMPAFTAELTAPFPPVGAP 632
             G P +       +   P PP GAP
Sbjct: 1175 EGSPGH-----PGQPGPPGPP-GAP 1193



 Score =  420 bits (1079), Expect = e-117
 Identities = 258/582 (44%), Positives = 294/582 (50%), Gaps = 76/582 (13%)

Query: 118 GEQGPRGEPGPRGPPGPPGLPGH----------------GIPGIKGKPGPQGYPG-VGKP 160
           G QGP GEPG  GP GPPG PG                 G PG +G PGP G  G  G P
Sbjct: 198 GYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP 257

Query: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQP 219
           G PGM G  G  G  G KGE G  G  G  G+PG  G PGP G  G  G+ G PGLPG  
Sbjct: 258 GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAA 317

Query: 220 GPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGA---------PGVKGPPGMHGPPGPVGLP 269
           G +G+ G +G  G  G  GP G  GF G PGA         PG  G PG  G PGP G  
Sbjct: 318 GARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA 377

Query: 270 GV----GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----GKPGQD 321
           G     G PG+ G PG +G +G  G PG PG  G  G PG  G  G PG+    G+PG++
Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKN 437

Query: 322 GIPGQPGFPGGKGEQGLPGLPGP---------PGLPGI----------GKPGFPGPKG-- 360
           G  G+PG  G +GE G+PG+PG          PG PG           G PGF GP G  
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497

Query: 361 ----DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGP---K 413
               ++G  G  GA GP G +G  G PG  G PG PG+ G+PG  G PG+ G PGP   +
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557

Query: 414 GEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP 473
           GE G  GP GP GP+G+PG+ GFPG  G  G  G  G RG PG  GP+G  G+ G  G  
Sbjct: 558 GESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQ 617

Query: 474 GVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIG 533
           G PG  GP G+ G  G  G QG  G+PG GGP G  G PG PGPKG+ G PG PG  G G
Sbjct: 618 GPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG--GKG 675

Query: 534 KPGVAGLHGPPGKPGALGPQGQPGLPGP---PGPPGPPGPPAVMPPTPPPQGEYLPDMGL 590
             G  G  GPPG  GA G +G  G PGP    G  GPPGPP     TP  QG      GL
Sbjct: 676 DAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGA-AGTPGLQGMPGERGGL 734

Query: 591 GIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
           G  G K        KG+ GGP  +          P  P+G P
Sbjct: 735 GSPGPK------GDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770



 Score =  407 bits (1046), Expect = e-113
 Identities = 254/600 (42%), Positives = 293/600 (48%), Gaps = 99/600 (16%)

Query: 112 PLASLRGEQGPRGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV---------- 157
           P A  R   G +G  GP+G PGPPG+PG     GIPG  G PG  G PG+          
Sbjct: 92  PTAPTRPPNG-QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQN 150

Query: 158 -----------------------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG 194
                                  G  G PG PG PG  G PG+ G  G +G  G  G  G
Sbjct: 151 YSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG 210

Query: 195 PQGPPGPHGLPG----------IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244
           P GPPGP G  G           G+PG PG  G PGP G +GP G+PG  G++G +G  G
Sbjct: 211 PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDG 270

Query: 245 ----FGMPGAPGVKGP---PGMHGPPGPVGLPGV----GKPGVTGFPGPQGPLGKPGAPG 293
                G  GAPG+KG    PG +G PGP+G  G     G+PG+ G  G +G  G  G+ G
Sbjct: 271 RNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDG 330

Query: 294 EPGPQGPIGVPGVQGPPGIPG----IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG 349
           +PGP GP G  G  G PG  G     G PG +G PGQ G PG +G  G  G PGPPG+  
Sbjct: 331 QPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN- 389

Query: 350 IGKPGFPGPKGDRGMGGVPGALGPRGEKGPI---GAPGIGGPPGEPGLPGIPGPMGP--- 403
            G PG  G  G  G+ G PG +G RG  GP    GAPG+ G  GEPG  G  G  GP   
Sbjct: 390 -GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE 448

Query: 404 ---PGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFL---------GEVGPPGM 451
               G  G PG KGE G  G  G PG  G PG  G  G PGF          GE GP G 
Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGE 508

Query: 452 RGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGP 511
           RG PGP GP+G AG+ G  G+PG PG+   +G PG PG  G  G PG PG  G SG  GP
Sbjct: 509 RGAPGPAGPRGAAGEPGRDGVPGGPGM---RGMPGSPGGPGSDGKPGPPGSQGESGRPGP 565

Query: 512 PGIPGPKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGP 570
           PG  GP+G+PG+ G PG  G  G PG  G  G PG PG  GP G+ G  GP GPPGP GP
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGP 625

Query: 571 PAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVG 630
                 T PP          G  G++     G   G+NG P    P    +  AP  P G
Sbjct: 626 GGDKGDTGPP----------GPQGLQGLPGTGGPPGENGKPG--EPGPKGDAGAPGAPGG 673



 Score =  387 bits (995), Expect = e-107
 Identities = 245/571 (42%), Positives = 269/571 (47%), Gaps = 93/571 (16%)

Query: 131 PPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPM 190
           PP  P  P +G        GPQG       G PG PG PG  G PG  G+ G  G  GP 
Sbjct: 91  PPTAPTRPPNG-------QGPQG-----PKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPP 138

Query: 191 GI--------------------------------PGPQGPPGPHGLPGI----GKPGGPG 214
           GI                                PGP GPPGP G PG     G PG PG
Sbjct: 139 GICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPG 198

Query: 215 LPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-------GMPGAPGVKGPPGMHGPPGPVG 267
             G PG  G  GP G PGP G  GP G  G        G PG  G+ GPPG+ GP G  G
Sbjct: 199 YQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPG 258

Query: 268 LPGV----------GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGK 317
            PG+          G+ G TG PG +G  G PG  G PGP GP G PG +G PG+PG   
Sbjct: 259 FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAA- 317

Query: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVP---GALGPR 374
                  G  G  G +G  G PG PGPPG  G   PG PG KG+ G  G P   GA G R
Sbjct: 318 -------GARGNDGARGSDGQPGPPGPPGTAGF--PGSPGAKGEVGPAGSPGSNGAPGQR 368

Query: 375 GEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQ 434
           GE GP G  G  GPPG PG+ G PG  G  G  G PG  G  G  GP GP G  G PGL+
Sbjct: 369 GEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLR 428

Query: 435 GFPGKPGFLGEVGPPGMR------GLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIP 488
           G  G+PG  G  G PG R      G+PG  G KGE G+ G PG PG  GL G  GE G P
Sbjct: 429 GGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAP 488

Query: 489 GDQGLQGPPGIPGIGGPSGPIGPPGIPGPK---GEPGLPGPPGFPGI-GKPGVAGLHGPP 544
           G +G  GP GIPG  GP+G  G PG  GP+   GEPG  G PG PG+ G PG  G  G  
Sbjct: 489 GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSD 548

Query: 545 GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDM-----GLGIDGVKPPH 599
           GKPG  G QG+ G PGPPGP GP G P VM    P   +  P       G G  G + P 
Sbjct: 549 GKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP 608

Query: 600 AYGAKKGKNGGPAYEMPAFTAELTAPFPPVG 630
               + G  G P    P      T P  P G
Sbjct: 609 GKNGETGPQGPPGPTGPGGDKGDTGPPGPQG 639



 Score =  374 bits (961), Expect = e-103
 Identities = 242/574 (42%), Positives = 273/574 (47%), Gaps = 120/574 (20%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-------HGIPGIKG 147
            P    GK   P    +       G +G  G PG RGPPG  G PG        G  G KG
Sbjct: 649  PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708

Query: 148  KPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG---------PQG 197
              GP G PG  G PG+ GMPG+ G +G PG KG+ G+ G  G  G+PG         P G
Sbjct: 709  AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 198  PPGPHGLPGI-GKPGGPGLPGQPGPKG---DRGPKGLPGPQGL---------------RG 238
            PPGP G PG  G+ G PGLPG  GP+G   +RG  G PGP G                RG
Sbjct: 769  PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828

Query: 239  PKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV-------GKPGVTGFPGPQGPLGKPGA 291
              G+KG G  G PGV GPPG  GP GP G  GV       G PG  GFPG +G  G PG+
Sbjct: 829  APGEKGEG--GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGS 886

Query: 292  PGEPGPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG- 349
             G PGP GP G PG  GPPG  G  G PG  G+ G  G  G  GE+G PG  GPPG PG 
Sbjct: 887  NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGP 946

Query: 350  ------------IGKPGFPGPKGDRGMGGV------PGALGPRGEKGPIGA---PGIGGP 388
                         G PG PGP+G  G  GV      PGA G  GE+GP G    PG+ G 
Sbjct: 947  LGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT 1006

Query: 389  PGEPGLPGIPGPMGPPGAIGFPGPKGEGGI------------VGPQGPPGPKGEPGLQGF 436
             GEPG  G PG  G PG  G PG KG+ G              GP GP GP G+ G +G 
Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE 1066

Query: 437  PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ------------KGVPGLPGVPGLLGPKGE 484
             G  G  G  GP G RG PGP GP+G+ G+            +G PG PG PG  GP G+
Sbjct: 1067 SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQ 1126

Query: 485  PGIPGDQGL---------QGPPGIPGIGGPSGPIGPPGIPGPKGE---------PGLPGP 526
             G  G  G           GPPG  G  G  GPIGPPG  G +GE         PG PGP
Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGP 1186

Query: 527  PGFP--------GIGKPGVAGLHGPPGKPGALGP 552
            PG P        G+G   +AG+ G   K G   P
Sbjct: 1187 PGPPGAPGPCCGGVGAAAIAGIGGE--KAGGFAP 1218



 Score =  329 bits (843), Expect = 6e-90
 Identities = 209/504 (41%), Positives = 236/504 (46%), Gaps = 67/504 (13%)

Query: 193 PGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAP 251
           P P+ P G         P  P  P  P  +G +GPKG PGP G+ G  GD G  G PG+P
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRP--PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSP 132

Query: 252 GVKGPPGM--HGPPGPVGLP----------GVGKPGVTGFPGPQGPLGKPGAPGEPGPQG 299
           G  GPPG+    P GP              GV   G+ G+PGP GP G PG PG  G  G
Sbjct: 133 GSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPG 192

Query: 300 PIGVPGVQGPPGIPG----------------IGKPGQDGIPGQPGFPGGKGEQGLPGLPG 343
             G PG QGPPG PG                 G  G+DG  G+PG PG +G  G PG+ G
Sbjct: 193 SPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKG 252

Query: 344 PPGLPGI----GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGP---PGE---PG 393
           P G+PG     G  GF G  G++G  G PG  G  G  G  GAPG  GP   PGE   PG
Sbjct: 253 PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPG 312

Query: 394 LPGI---------------PGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPG 438
           LPG                PGP GPPG  GFPG  G  G VGP G PG  G PG +G PG
Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372

Query: 439 KPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPG 498
             G  G  GPPG  G+ G  G KGE G  G+PG PG+ G  GP G  G  G  GL+G  G
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432

Query: 499 IPGIGGPSGPIGP---------PGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPG 548
            PG  G  G  GP         PG+PG KGE G  G PG PG  G PG AG  G PG  G
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRG 492

Query: 549 ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN 608
             GP G PG  GP G  G PGP         P  + +P  G G+ G+          GK 
Sbjct: 493 PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPG-GPGMRGMPGSPGGPGSDGKP 551

Query: 609 GGPAYEMPAFTAELTAPFPPVGAP 632
           G P  +  +       P  P G P
Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQP 575



 Score = 37.0 bits (84), Expect = 0.067
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 93   IQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQ 152
            + P+   GK+        I     RG +G RG  G  G PG PG PG       G PGP 
Sbjct: 1142 VGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP-----PGAPGP- 1195

Query: 153  GYPGVGKPGMPGMPGK 168
               GVG   + G+ G+
Sbjct: 1196 CCGGVGAAAIAGIGGE 1211


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  426 bits (1095), Expect = e-119
 Identities = 250/572 (43%), Positives = 285/572 (49%), Gaps = 89/572 (15%)

Query: 84  PHLPQYMKEIQPAPRMGKEAVPKKGKEIP-LASLRGEQGPRGEPGPRGPPGPPGLPG--- 139
           P LP       P PRM  E  PK  K  P L    G QG  GE GP+GP GPPG  G   
Sbjct: 330 PGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEG 389

Query: 140 -HGIPGIKGKPG---------PQGYPG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIG 188
            HG PG  G PG         P G PG VG PG+ G PGK G  G  GA GE G  G +G
Sbjct: 390 AHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVG 449

Query: 189 PMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248
           P G PG  G PGP G    G+PG  G PG PGP G +G +G PG  G  G +GD G G+ 
Sbjct: 450 PRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVA 509

Query: 249 GAPGVKGPPGMHGPPGPVGLPGV------------------------------------- 271
           G PG  GPPG  G PG  GLPG                                      
Sbjct: 510 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPP 569

Query: 272 GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-------------IGKP 318
           G PG+ GF G +G  GKPG  G  G +G  G PG+ GPPGI G             +G+ 
Sbjct: 570 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK 629

Query: 319 GQDGIPGQPGF---PGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPR 374
           G  G PG PGF   PG  G  G  G+ G  G PGI G PG  GP G +G  G+PG  G  
Sbjct: 630 GDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEE 689

Query: 375 GEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQ 434
           G++G  G PG  G PG+ G PG+PGP G  G  GF G  G+ G  GP+G  G  G PG +
Sbjct: 690 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 749

Query: 435 GFPGKPGFLGEVGP---------------PGMRGLPGPIGPKGEAGQKGVPGLPGVPGLL 479
           G PGK G  G  GP               PG  G PGP G  G+ G KG  G PG+PG L
Sbjct: 750 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFL 809

Query: 480 GPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAG 539
           GP+G PG PG++G+ G  G+PG  G  G  G  G PG KG+ G PG     G G+PG  G
Sbjct: 810 GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG-----GKGQPGDPG 864

Query: 540 LHGPPGKPGALGPQGQPGLPGPPGPPGPPGPP 571
           + G  G  G +GPQG PG  GP GPPGPPG P
Sbjct: 865 IPGHKGHTGLMGPQGLPGENGPVGPPGPPGQP 896



 Score =  399 bits (1026), Expect = e-111
 Identities = 250/588 (42%), Positives = 288/588 (48%), Gaps = 107/588 (18%)

Query: 124 GEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQ 183
           GEPG RG  G PG PG     ++G+ G QG    G+PG  G  G PGA G PG +GE G 
Sbjct: 250 GEPGERGEDGLPGKPG-----LRGEIGEQGL--AGRPGEKGEAGLPGAPGFPGVRGEKGD 302

Query: 184 KGEIGPMGIP---------GPQGPPGPHGLPGIGK--PGGPGLPGQPGPKGDRGPKGLP- 231
           +GE G +G+P         G  GP GP GLPG        P +PG+ GPKG++G  GLP 
Sbjct: 303 QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG 362

Query: 232 -----------GPQGLRGPKGDKG----FGMPGAPGVKGPPGMHGPPGPVGLPG-VGKPG 275
                      GPQG  GP G KG     G PGA G  G PG  G PGP G PG VG PG
Sbjct: 363 EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG 422

Query: 276 VTGFPGPQGPLGKPGAPGE---PGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFP-- 330
           + G PG  G  G+ GA GE   PGP GP G PG  G PG PG GK G+ G+ G PG P  
Sbjct: 423 LRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGP 482

Query: 331 -GGKGEQGLPGLPGPPGL---PGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIG 386
            G KG++G PG+PG PG    PGIG  G PGP G  G  G PG+ G  G  GP G  G  
Sbjct: 483 LGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD 542

Query: 387 G---------------------PPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPP 425
           G                     PPG PGLPG+PG  G  G  G PG +G  G  G  GPP
Sbjct: 543 GLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPP 602

Query: 426 GPKGEPGL---------------------QGFPGKPGFL---------------GEVGPP 449
           G  G PG+                     QG PG PGF+               G  GPP
Sbjct: 603 GLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP 662

Query: 450 GMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPI 509
           G++G PG  GP G  G  G+PG+PG  G  G  G+PG PG+ G  G PG+P   GP G  
Sbjct: 663 GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP---GPEGAR 719

Query: 510 GPPGIPGPKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPP 568
           GPPG  G  G+ G PGP G  G +G PG  GL G  G  G  GPQG  G  GPPG  G P
Sbjct: 720 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779

Query: 569 GPPAVMPP--TPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYE 614
           G P    P  TP  +G    +   G+ G   P     + G+ G P  E
Sbjct: 780 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 827



 Score =  370 bits (951), Expect = e-102
 Identities = 246/578 (42%), Positives = 282/578 (48%), Gaps = 110/578 (19%)

Query: 158 GKPGMPGMPGKPGAMGM---PGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI------- 207
           G   + G PG+ G  G+   PG +GEIG++G  G  G  G  G PG  G PG+       
Sbjct: 244 GLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 303

Query: 208 GKPGGPGLPGQPGPKGDRGPKGLPGPQGL----------------RGPKGDKGF-GMPGA 250
           G+ G  GLPG  G +G++G  G  GP GL                +GPKG+KG  G+PG 
Sbjct: 304 GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE 363

Query: 251 PGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGP---IGVPGV 306
           PG++G PG  GP GP G PG  G+ G  G PG  G  G PG  G PGP GP   +G PG+
Sbjct: 364 PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGL 423

Query: 307 QGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGL-----PGI-GKPGFPGP- 358
           +G PG  G  G+ G  G  G PG  G +G+ G PGLPGPPG      PG+ G PG PGP 
Sbjct: 424 RGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPL 483

Query: 359 --KGDRGMGGVPGALGPRGE--------KGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIG 408
             KGDRG  G+PG+ G RG+         GP G PG  G PG  GLPG PGP GP G  G
Sbjct: 484 GTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDG 543

Query: 409 FPGPKGEGGI------VGPQGPPGPKGEPGLQGF------PGKP------GFLGEVGPPG 450
                  G I      V    PPGP G PGL GF      PGKP      G  GE GPPG
Sbjct: 544 LSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPG 603

Query: 451 MRGLPGPIGPK---------GEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGL---QGPPG 498
           + G PG  GP+         GE GQKG  G PGVPG +GP G PG PG  G+    GPPG
Sbjct: 604 LPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG 663

Query: 499 I---PGIGGPSGPIGPPGIPGPKGE------PGLPGPPGFPG----IGKPGVAGLHGPP- 544
           I   PG  GP GP GP G+PG  GE       G PGPPG PG     G PG  G  GPP 
Sbjct: 664 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 723

Query: 545 --------------GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGL 590
                         G+ GA+G  GQ GLPG  G  GP GP     P  PP     P    
Sbjct: 724 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG-SP 782

Query: 591 GIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPP 628
           G  G          KG+NG P   +P F      P  P
Sbjct: 783 GEPGPSGTPGQKGSKGENGSPG--LPGFLGPRGPPGEP 818



 Score =  246 bits (628), Expect = 6e-65
 Identities = 160/383 (41%), Positives = 185/383 (48%), Gaps = 21/383 (5%)

Query: 236 LRGPKGDKGFGMP-GAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFP-----GPQGPLGKP 289
           L GP+ D    +  GA G  G       P  V  P    P  TG       G QGP  + 
Sbjct: 170 LLGPRTDPWENVDQGAQGACGRGNTSVLPSSVA-PQCSMPKGTGHEFSAALGTQGPADQR 228

Query: 290 GAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG 349
                         PG++   G PG  + G+DG+PG+PG  G  GEQGL G PG  G  G
Sbjct: 229 ADARASCILAAKTAPGLKQLNGEPG--ERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 286

Query: 350 I-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP-PGAI 407
           + G PGFPG +G++G  G  G LG  G KG  G  G  GP G PGLPG      P P   
Sbjct: 287 LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 346

Query: 408 GFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQK 467
           G  GPKGE      +G PG  GEPGLQG PG+ G  G  GPPG +G  G  G  G AG  
Sbjct: 347 GEQGPKGE------KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNP 400

Query: 468 GVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527
           G PG  G PG  GP G  G PG +G  G  G  G  G +G  G PG  GP+G+PG PG P
Sbjct: 401 GAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLP 460

Query: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP----PQGE 583
           G PG GK G  GL G PG PG LG +G  G PG PG PG  G P +    PP    P G+
Sbjct: 461 GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGD 520

Query: 584 YLPDMGLGIDGVKPPHAYGAKKG 606
                  G+ G   P     + G
Sbjct: 521 KGSPGSRGLPGFPGPQGPAGRDG 543



 Score =  166 bits (421), Expect = 6e-41
 Identities = 117/295 (39%), Positives = 139/295 (47%), Gaps = 52/295 (17%)

Query: 53   PLGQQVPHMPLAKDGL--AMGKEMPHLQYGKE-------YPHLPQYMKEIQPAPRMG--- 100
            P G Q P  P  K+G   + G+  P    G++        P LP ++    P    G   
Sbjct: 763  PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKG 822

Query: 101  ---KEAVPKKGKEIPLASLRGEQGPRGEPGP---RGPPGPPGLPGHGIPGIKGKPGPQGY 154
               KE VP K  E      RG+ G +G+ GP   +G PG PG+PGH   G  G  GPQG 
Sbjct: 823  VPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGH--KGHTGLMGPQGL 880

Query: 155  PG----VGKPGMPGMPGKPGAMGMPGA--------KGEIGQKGEI--------------- 187
            PG    VG PG PG PG PG  G   +        + E+G++ E                
Sbjct: 881  PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMK 940

Query: 188  GPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGM 247
               G PGP GPPG  GLPG  + G  G PG+PG  G  GP G  GP+G RG KGD G   
Sbjct: 941  SSQGRPGPPGPPGKDGLPG--RAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG 998

Query: 248  PGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302
             G  G  GPPG+ G PG    PG  K G+ G PGPQG  G  G PG PGP GP G
Sbjct: 999  VGLRGEMGPPGIPGQPGE---PGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1050


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  425 bits (1092), Expect = e-119
 Identities = 261/591 (44%), Positives = 305/591 (51%), Gaps = 66/591 (11%)

Query: 98  RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIP-GIKGKPGPQGYPG 156
           R+G +  P +     +    G  GP G PG  G PG PG+ G   P G +G  GPQG  G
Sbjct: 346 RLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG 405

Query: 157 -VGKPGMPGMPGKPGAM---GMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG----IG 208
             G PG  G PG PGA+   G PGAKG  G  G  GP G  GP G PGP G  G     G
Sbjct: 406 ETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465

Query: 209 KPGGPGLP---------GQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPG 258
           +PG PG+P         G+PGP G +GP G PG +G RGP+GD G  G PG  G +G PG
Sbjct: 466 QPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525

Query: 259 MHGPPGPVGLPG----VGKPGVTGFPGPQGPLGKPGAPGE---PGPQGPIGVPGVQGPPG 311
             G PG  GLPG     G+ G  G  GP+G  G PG PGE   PG +G  G PGVQGP G
Sbjct: 526 NRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEG 585

Query: 312 IPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPG 369
             G +G PG+DG PG PG  G +G+ G  GLPGP G  G  GKPG  G  G  G  G PG
Sbjct: 586 KLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPG 645

Query: 370 ALGPRGEKGPIGAPGIG------GPPGEPGLPGIPGPMGPPGAIGFPGPK---GEGGIVG 420
             G  G  GP+G PG+       GPPG  G  G+PGP GPPG  G PG +   G+ G VG
Sbjct: 646 KDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVG 705

Query: 421 PQGP------PGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP- 473
           P GP      PG +GEPG+ G PG+ G  G  GP G +G PGP G  G+ G  G+ G+P 
Sbjct: 706 PLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPG 765

Query: 474 --GVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG 531
             G+ G  GPKG+ G  G++G +G  G  G  G  GP+GPPG  GP GE G PGP G  G
Sbjct: 766 ERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVG 825

Query: 532 ----IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPD 587
                G PG  G +GP G  G  GPQG  G PG  G PG PG       +P PQ      
Sbjct: 826 PPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG-DAGSPGPQ------ 878

Query: 588 MGLGIDGVKPPHAYGAKKGKNGGPAYEMP------AFTAELTAPFPPVGAP 632
              G+ G   PH      G  GG   + P        +A    P  P GAP
Sbjct: 879 ---GLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAP 926



 Score =  425 bits (1092), Expect = e-119
 Identities = 266/585 (45%), Positives = 306/585 (52%), Gaps = 74/585 (12%)

Query: 55   GQQVPHMPLAKDGLA--MGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVP-KKGKEI 111
            G+  P  P+   GLA   G++ P    G  +  LP          + G + VP   G   
Sbjct: 648  GEVGPSGPVGPPGLAGERGEQGPPGPTG--FQGLPGPPGPPGEGGKPGDQGVPGDPGAVG 705

Query: 112  PLASLRGEQGPRGEPGPRGPPGPPGLPG-------HGIPGIKGKPGPQGYPG-VGKPGMP 163
            PL    G +G RG PG RG PG  GLPG       HG  G KG PGP G PG  G PG+ 
Sbjct: 706  PL----GPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQ 761

Query: 164  GMPGKPGAMGMPGAKGE---IGQKG------EIGPMGIPGPQGPPGPHGLPGI-GKPGGP 213
            GMPG+ G  G PG KG+   IG+KG        G  G+PGP GPPGP G  G  G+PG  
Sbjct: 762  GMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPR 821

Query: 214  GLPGQPGPKGD------------------RGPKGLPGPQGLRGPKGDKG-FGMPGAPGVK 254
            GL G PG +G+                  +GP G PG +G  G  G KG  G PG  G+ 
Sbjct: 822  GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLA 881

Query: 255  GPPGMHGPPGPVGLPG----VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP 310
            G PG HGP G  GL G     G PG TGFPG  G +G PG  G PGP GP+G PG +GPP
Sbjct: 882  GSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPP 941

Query: 311  GIPG-------IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPK 359
            G+ G       +G  G  G PG PG  G  GE G PG  GPPG  G     G  G PG +
Sbjct: 942  GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQR 1001

Query: 360  GDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGI------PGPMGPPGAIGFPGPK 413
            G+RGM G+PG  G  G+ GP GA G  GPPG  G PG       PGP GP G  G PG  
Sbjct: 1002 GERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061

Query: 414  GEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP---GPIGPKGEAGQKGVP 470
            G  G  G +G PGP G PG QG PG PG +G  G  G RG P   GPIGP G AG++G+P
Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP 1121

Query: 471  GLPGV---PGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527
            G  G     G  G +G+ G  G +G  G  G+PG  GP+G  G  GIPGP G  G PGP 
Sbjct: 1122 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPV 1181

Query: 528  GFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPP 571
            G  G  G PG  G  GPPG  G++G  G  G PG PGPPGPPGPP
Sbjct: 1182 GPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPP 1226



 Score =  422 bits (1084), Expect = e-118
 Identities = 271/651 (41%), Positives = 314/651 (48%), Gaps = 136/651 (20%)

Query: 118 GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-------GKPGMPGMPGKP 169
           G+ GP G  G RGP GPPG PG  G PG  G PG  G+ G        G PG+PG+ G  
Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHR 302

Query: 170 GAMGMPGAKGEIG---QKGEIGPMGIPGPQGPPGPHGLPG-------------------- 206
           G  G+ G KGE+G    KGE GP G  G  GP GP G+PG                    
Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMP 362

Query: 207 --------IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-------GMPGA- 250
                   +G PG  G PG PG KG+ GP G  GP+G +G +G+ G        G+PGA 
Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422

Query: 251 -----PGVKGP---PGMHGPPGPVGLPGV----------------GKPGVTGFPGPQGPL 286
                PG KGP   PG  GPPG  G PG                 G PGV GF G  GP 
Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482

Query: 287 GKPGA---------PGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKG-- 334
           G+PG          PGE G +GP G PG  GPPG  G  G PG  G PG  G PG KG  
Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQ 542

Query: 335 -EQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPP--- 389
            E+G  G  GP G  G  G+PG PG  G RG+ G PG  GP G+ GP+GAPG  G P   
Sbjct: 543 GERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP 602

Query: 390 ------GEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFL 443
                 G+PG  G+PGP G  G  G PG  G  G+ G +G PG  GE G  G  G PG  
Sbjct: 603 GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLA 662

Query: 444 GE------VGPPGMRGLPGPIGPKGEAGQ---KGVPGLPGVPGLLGPKGEPGIPGDQ--- 491
           GE       GP G +GLPGP GP GE G+   +GVPG PG  G LGP+GE G PG++   
Sbjct: 663 GERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEP 722

Query: 492 GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPGAL 550
           G+ G PG  G+ G  GP GP G PGP G PG  GPPG  G+ G+ G+AG  GP G  G +
Sbjct: 723 GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI 782

Query: 551 GPQGQP---------GLPGPPGPPGPPGPPA----------VMPP----TPPPQGEYLPD 587
           G +G           GLPGP GPPGP GP            V PP     P  +GE  P 
Sbjct: 783 GEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPT 842

Query: 588 MGLGIDGVKPPHAYGAKKGKNGGPAYE------MPAFTAELTAPFPPVGAP 632
             +G  G + P      KG+ G P  +       P   A    P  P G P
Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893



 Score =  422 bits (1084), Expect = e-118
 Identities = 255/602 (42%), Positives = 299/602 (49%), Gaps = 73/602 (12%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQG 153
            P    G + +  +  +  +   +GE GP+GEPGP G  GP G PG  G  G +G PG  G
Sbjct: 454  PQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVG 513

Query: 154  YPG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG------ 206
             PG VG+ G PG  G PG+ G+PG KG  G++G +G  G  G QG PG  G PG      
Sbjct: 514  PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARG 573

Query: 207  -------------IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG--------- 244
                         +G  G PG  G+PGP G  G +G PG  GL GPKG  G         
Sbjct: 574  LTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG 633

Query: 245  -FGMPGAPGVKGPPGMHGPPGPVGLPGV-------GKPGVTGFPGPQGPLGKPGAPGEPG 296
              G+PG  G  G  G  GP GPVG PG+       G PG TGF G  GP G PG  G+PG
Sbjct: 634  NAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPG 693

Query: 297  PQGPIGVPGVQGPPGIPG-------IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG 349
             QG  G PG  GP G  G        G+PG  G+PG+ G  GG G  G  G PGP G PG
Sbjct: 694  DQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPG 753

Query: 350  -IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIG 408
              G PG  G  G+RG+ G P   GP+G++G IG  G  G  G  G  G+PGP+GPPG  G
Sbjct: 754  DTGPPGLQGMPGERGIAGTP---GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG 810

Query: 409  FPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGP------PGMRGLPGPIGPKG 462
              G KGE G  G  GPPG +G PG +G  G  G +G  GP      PG++G PG  G KG
Sbjct: 811  PTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG 870

Query: 463  EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIG------GPSGPIGPPGIPG 516
            +AG  G  GL G PG  GP G PG+ G +G QGPPG  G        GP GP G PG  G
Sbjct: 871  DAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG 930

Query: 517  PKGEPGLPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV-- 573
            P GEPG  GPPG  G  G  G  G  GP G PG  G +G PG  G PGP GPPGP     
Sbjct: 931  PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG 990

Query: 574  ---MPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVG 630
               +   P  +GE       G+ G+  P     K G  G    + P           PVG
Sbjct: 991  QRGIVGMPGQRGE------RGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVG 1044

Query: 631  AP 632
             P
Sbjct: 1045 EP 1046



 Score =  411 bits (1056), Expect = e-114
 Identities = 256/582 (43%), Positives = 293/582 (50%), Gaps = 95/582 (16%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYP------GVGKP---GMPG--- 164
           RGE+GP+G PGPRGP G  G P  G+PG  G PGP G+P      G+ +P    M G   
Sbjct: 143 RGERGPKGRPGPRGPQGIDGEP--GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDE 200

Query: 165 ----------MPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPG 214
                     MPG  G +G  G +G  GQ+G  GP G PG  G PGP G   IG  G  G
Sbjct: 201 KSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMG--PIGSRGPEG 258

Query: 215 LPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGVK---GPPGMHGPPGPVGLPG 270
            PG+PG  G+ G  G PG  G  G  G +GF G PG PG+K   G  G+ GP G VG PG
Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG 318

Query: 271 ----VGKPGVTGFPGPQGPLGKP------------------GAPGEPGPQGPIGVPGVQG 308
                G  G  G  GP GP G P                  G PG+PGP GP+G+PG  G
Sbjct: 319 SKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSG 378

Query: 309 PPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPKGDRG 363
            PG PG+ G+ G  G  G  G  G +GE G PG  G PGLPG     G PG  GP G  G
Sbjct: 379 FPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPG 438

Query: 364 MGGVPGALGPRGEKGP---IGAPGIGGPPGEPGLP---------------GIPGPMGPPG 405
             G PG+ GP G  GP    G  GI G PG+PG+P               GI GP+GPPG
Sbjct: 439 TSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPG 498

Query: 406 AIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAG 465
             G  GP+G+ G VGP GP G +G PG +GFPG  G  G  G  G RG  G  GPKG  G
Sbjct: 499 EEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQG 558

Query: 466 QKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPG 525
             G PG PG+PG  G  G PG+ G +G  GP G PG  G  GP G  GI G  G  GLPG
Sbjct: 559 DPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPG 618

Query: 526 PPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPP---------GPPGPPAVM- 574
           P G  G  GKPG AG  G PG+ GA G  G+ G  GP GPP         GPPGP     
Sbjct: 619 PKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQG 678

Query: 575 ---PPTPPPQGEYLPDMGLGIDGVKPPHAYG--AKKGKNGGP 611
              PP PP +G    D G+  D    P A G    +G+ G P
Sbjct: 679 LPGPPGPPGEGGKPGDQGVPGD----PGAVGPLGPRGERGNP 716



 Score =  409 bits (1051), Expect = e-114
 Identities = 255/596 (42%), Positives = 293/596 (49%), Gaps = 83/596 (13%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQGYPG-VGKPGMPGMPGKPGAMGMP 175
            G+ GP G PG  G PGPPG  G  G PG  G PGP+G  G  GKPG  G  G PG  G P
Sbjct: 585  GKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAP 644

Query: 176  GAKGEIGQKGEIGPMGIPGP---QGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPG 232
            G  GE+G  G +GP G+ G    QGPPGP G  G+  PG PG PG+ G  GD+G  G PG
Sbjct: 645  GKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGL--PGPPGPPGEGGKPGDQGVPGDPG 702

Query: 233  PQGLRGPKGDKGF-------GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQG 284
              G  GP+G++G        G+ G PG KG  G HGP GP G PG  G PG TG PG QG
Sbjct: 703  AVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQG 762

Query: 285  PLGKPGAPGEPGPQG------------------------PIGVPGVQGPPGIPG------ 314
              G+ G  G PGP+G                        P+G PG  GP G  G      
Sbjct: 763  MPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRG 822

Query: 315  -IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGD------RGMGG 366
             +G PG  G PG  G  G  G  G  G  GP G PG+ G+PG PG KGD      +G+ G
Sbjct: 823  LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAG 882

Query: 367  VPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPG 426
             PG  GP G  G  G  G  GPPG  G PG  G +GPPG  G PGP G  G  G +GPPG
Sbjct: 883  SPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPG 942

Query: 427  PKGEPGL------QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
             +G+PG       +G  G PG  G+ G PG  G PGP GP G AG  G  G+ G+PG  G
Sbjct: 943  LRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRG 1002

Query: 481  PKGEPGIPGDQGLQ---GPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI----- 532
             +G PG+PG  G     GP G  G  GP GP+GPPG  GP GEPG  GP G  G      
Sbjct: 1003 ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062

Query: 533  --------GKPGVAGLHGPPGKPGALGPQGQP---GLPGPPGPPGPPGPPA-----VMPP 576
                    G PG AGL G  G PG  GP G P   G  G PG  GP GPP       +P 
Sbjct: 1063 AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPG 1122

Query: 577  TPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
               P+G+       G  G K    +   +G  G P       +A +  PF P G P
Sbjct: 1123 PQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPP 1178



 Score =  404 bits (1039), Expect = e-112
 Identities = 258/583 (44%), Positives = 284/583 (48%), Gaps = 115/583 (19%)

Query: 113  LASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV----------GKPGM 162
            LA  RGEQGP G  G +G PGPPG PG G     GKPG QG PG           G+ G 
Sbjct: 661  LAGERGEQGPPGPTGFQGLPGPPGPPGEG-----GKPGDQGVPGDPGAVGPLGPRGERGN 715

Query: 163  PGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGP 221
            PG  G+PG  G+PG KG  G  G  GP G PGP G PG  G PG+ G PG  G+ G PGP
Sbjct: 716  PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGP 775

Query: 222  KGDRG---------------PKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHGPPGP 265
            KGDRG                +GLPGP G  GP G  G  G PG  G+ GPPG  G PG 
Sbjct: 776  KGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGS 835

Query: 266  VGLPGVGKPGVTGFPGPQGPLGKPGAPGEPG------------PQGPIGVPGVQGPPGIP 313
             G  G    G  GF GPQGP G+PG  GEPG            PQG  G PG  GP G+P
Sbjct: 836  RGENG--PTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893

Query: 314  GI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGAL 371
            G+ G  G  G PG  GFPG  G  G PG  G PG  G +G+PG  GP G RG  G  G +
Sbjct: 894  GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRV 953

Query: 372  GPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGA------IGFPGPKGEGGIVGPQGPP 425
            G RG  GP G PG  G PGE G PG  GP GP G       +G PG +GE G+ G  GP 
Sbjct: 954  GDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPA 1013

Query: 426  GPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEP 485
            G  G+ G  G  G  G  G VGPPG  G  G  GP+G AG  G PG  G  G  G +G+P
Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073

Query: 486  GIPGDQGLQGPPGIPG-IGGPS-----------GPIGPPG------IPGPKGE------- 520
            G  G  G QG PG PG +G P            GPIGPPG      +PGP+G        
Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDH 1133

Query: 521  -----------------PGLPGPPGFPG----IGKPGVAGLHGPPGKPGALGPQGQPGLP 559
                              GLPGPPG  G     G PG  G  GPPG  G  G +G PG  
Sbjct: 1134 GDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPL 1193

Query: 560  GPPGPP------------GPPGPPAVMPPTPP-PQGEYLPDMG 589
            GP GPP            GPPG P   PP PP P G     +G
Sbjct: 1194 GPIGPPGVRGSVGEAGPEGPPGEPG--PPGPPGPPGHLTAALG 1234



 Score =  395 bits (1016), Expect = e-110
 Identities = 244/573 (42%), Positives = 286/573 (49%), Gaps = 70/573 (12%)

Query: 100 GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV-G 158
           G+    +KG+   +  + G +G  G  GP G  GP      G  G KG+PGP+G  G+ G
Sbjct: 108 GRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGP-----RGERGPKGRPGPRGPQGIDG 162

Query: 159 KPGMPGMPGKPGAMGMPGAKGEIG------------------------QKGEIGPMGIPG 194
           +PG+PG PG PG  G P   G  G                          G +GP+G  G
Sbjct: 163 EPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRG 222

Query: 195 PQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGV 253
           PQG  G  G  G G  G PG PG PGP G  G +G  GP G  G  G+ G  G PG  G 
Sbjct: 223 PQGLQGQQG--GAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGF 280

Query: 254 KGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI 312
            G PG  G PG  GLPG+ G  G  G  GP+G +G PG+ GE GP GP+G  G  GP G+
Sbjct: 281 AGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM 340

Query: 313 PG-------IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMG 365
           PG        G PGQ G  G PG PG  G  G+PG  G PG PG+   G  GP G RG  
Sbjct: 341 PGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGM--KGEAGPTGARGPE 398

Query: 366 GVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPP 425
           G  G  G  G  GP+G+PG+ G  G  G PG  GP G PG  G PG  G  G  GPQG  
Sbjct: 399 GPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGST 458

Query: 426 GPKGEPGLQGFPGKPGFLGEVGP---PGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPK 482
           GP+G  G  G PG PGF GE GP   PG  G+ GPIGP GE G++G  G PG  G  GP 
Sbjct: 459 GPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV 518

Query: 483 GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPK---GEPGLPGPPGFPG----IGKP 535
           GE G PG++G  G  G+PG  G  G  GP G  GPK   G+PG PG PG PG     G P
Sbjct: 519 GERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNP 578

Query: 536 GVAGLHGP------------PGKPGALGPQGQP---GLPGPPGPPGPPGPP--AVMPPTP 578
           GV G  G             PG PG++G +GQP   GLPGP G  G PG P  A     P
Sbjct: 579 GVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVP 638

Query: 579 PPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP 611
             +G    D  +G  G   P     ++G+ G P
Sbjct: 639 GQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPP 671



 Score =  354 bits (909), Expect = 1e-97
 Identities = 214/487 (43%), Positives = 248/487 (50%), Gaps = 70/487 (14%)

Query: 169 PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGP 227
           PG       +G  GQKGE G + +           + GI G+PG  G PG  GP+G+RGP
Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPV-----------VTGIRGRPGPAGPPGSQGPRGERGP 148

Query: 228 KGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGL------------------- 268
           KG PGP+G +G  G+   G+PG PG  GPPG    PGP GL                   
Sbjct: 149 KGRPGPRGPQGIDGEP--GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGS 206

Query: 269 -----PG----VGKPGVTGFPGPQ---GPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-I 315
                PG    VG  G  G  G Q   GP G PG PG+PGP GPIG  G +GPPG PG  
Sbjct: 207 QVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGED 266

Query: 316 GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPR 374
           G+PG++G PG+ GF G  G +G PG PG PGL G  G  G  GPKG+       GA G +
Sbjct: 267 GEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGE------VGAPGSK 320

Query: 375 GEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQ 434
           GE GP G  G  GP G  G+PG  G +GP GA   PG +G  G+ G  GP GP G PG  
Sbjct: 321 GEAGPTGPMGAMGPLGPRGMPGERGRLGPQGA---PGQRGAHGMPGKPGPMGPLGIPGSS 377

Query: 435 GFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQ 494
           GFPG PG  GE GP G RG  GP G +GE G  G  G PG+PG +G  G PG  G  G  
Sbjct: 378 GFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSP 437

Query: 495 GPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-------GKPGVAGLH---GPP 544
           G  G PG  GP G  GP G  GP+G  G PG PG PG        G+PG  G+    GPP
Sbjct: 438 GTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPP 497

Query: 545 GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAK 604
           G+ G  GP+G PG  GPPGP G  G P        P  + LP    G  G + P      
Sbjct: 498 GEEGKRGPRGDPGTVGPPGPVGERGAPG---NRGFPGSDGLPG-PKGAQGERGPVGSSGP 553

Query: 605 KGKNGGP 611
           KG  G P
Sbjct: 554 KGSQGDP 560



 Score =  206 bits (523), Expect = 8e-53
 Identities = 146/401 (36%), Positives = 167/401 (41%), Gaps = 101/401 (25%)

Query: 330 PGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGP- 388
           PGG       G  G  G PG+  P   G +G  G  G PG+ GPRGE+GP G PG  GP 
Sbjct: 100 PGGGNTNFGRGRKGQKGEPGL-VPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQ 158

Query: 389 --PGEPGLPGIPGPMGPPGAIGFPGP---------------------------------- 412
              GEPG+PG PG  GPPG    PGP                                  
Sbjct: 159 GIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPV 218

Query: 413 --------KGEGGIVGPQGPPGPKGEP------GLQGFPGKPGFLGEVGPPGMRGLPGPI 458
                   +G+ G  GP GPPG  G+P      G +G  G PG  GE G PG  G PG +
Sbjct: 219 GPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEV 278

Query: 459 GPKGEAGQKGVPGLPGVPGLL---------GPKGEPGIPGDQGLQGPPGIPGIGGPSGP- 508
           G  G  G +G PG PG+PGL          GPKGE G PG +G  GP G  G  GP GP 
Sbjct: 279 GFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR 338

Query: 509 --------IGP------------PGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPG 548
                   +GP            PG PGP G  G+PG  GFP  G PG+ G  GP G  G
Sbjct: 339 GMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFP--GNPGMKGEAGPTGARG 396

Query: 549 ALGPQGQPGLPGPPGPPGPPGPPAVM--------------PPTPPPQGEYLPDMGLGIDG 594
             GPQGQ G  GPPGP G PG P  +              P T  P G   P    G  G
Sbjct: 397 PEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQG 456

Query: 595 VKPPHAYGAKKGKNGGPAYEMPAFTAELTAPF---PPVGAP 632
              P     + G  G P ++  A       P     P+G P
Sbjct: 457 STGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPP 497


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  421 bits (1083), Expect = e-117
 Identities = 259/559 (46%), Positives = 289/559 (51%), Gaps = 65/559 (11%)

Query: 87   PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGI 145
            P       P P     ++       P   L G  GP+G+ G  GPPG PGLPG  G  G 
Sbjct: 594  PAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGP 653

Query: 146  KGKPGPQGYPGV-------GKPGMPGM-PGK-----------PGAMGMPGAKGEIGQKGE 186
            +G PGP G PG+       G+ G PG+ PGK           PG  G PG  G  G KG 
Sbjct: 654  RGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGY 713

Query: 187  IGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPG---QPGPKGDRGPKGLPGPQGLRGPKGD 242
             GP G PG QG PGP G PG  G PG  GLPG    PGPKG RG  GLPG  GL G  G+
Sbjct: 714  PGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGE 773

Query: 243  KGF----------GMPGAPGV---KGPPGMHGPPGPVGLPG----------VGKPGVTGF 279
            +G           GMPG PGV   +GPPG+ G PG +GLPG          +G  G  G+
Sbjct: 774  RGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGY 833

Query: 280  PGPQGPLGKPGAPGEPG---PQGPIGVPGVQGPPGIPGI-------GKPGQDGIPGQPGF 329
            PGP+G  G  G+ GEPG    +G  GVPGV G PG  G        G PG  G PG  G 
Sbjct: 834  PGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGK 893

Query: 330  PGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGP 388
             G KG  G PG PGP G PG IG PG  GP+G +G  G  G  GPRG+ GP G  G  GP
Sbjct: 894  VGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGP 953

Query: 389  PGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGP 448
            PG PGL G PG  G PG  G  G KGE G  G  GP G +G  G  G  G+PG +GE G 
Sbjct: 954  PGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGD 1013

Query: 449  PGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGP 508
             GM G PG  GPKG  G  G+PG  G PG  GP+G PG  G  G++G  G  G  GP GP
Sbjct: 1014 RGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGP 1073

Query: 509  IGPPGIPGPKGEPGLPGPPGFPG----IGKPGVAGLHGPPGKPGALGP---QGQPGLPGP 561
             G  G  G KG PG  G PG PG     G+ G  G  G PG PG  GP   +G PG PGP
Sbjct: 1074 AGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGP 1133

Query: 562  PGPPGPPGPPAVMPPTPPP 580
             GP GP GPP  M P  PP
Sbjct: 1134 QGPQGPIGPPGEMGPKGPP 1152



 Score =  413 bits (1061), Expect = e-115
 Identities = 287/717 (40%), Positives = 341/717 (47%), Gaps = 169/717 (23%)

Query: 41   PPQMP--PQIPQYQPLGQQVPHMPLAKDGL-----AMG-KEMPHLQYGKEYPH------L 86
            PP +P  P IP  +  G + P  P    GL     A G K  P L  GK +        L
Sbjct: 638  PPGLPGLPGIPGAR--GPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGL 695

Query: 87   PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGI 145
            P       P  R G +  P            G  G +G+PGP G PG  G PG  G+PG 
Sbjct: 696  PGLSGNPGPPGRKGHKGYPGPA---------GHPGEQGQPGPEGSPGAKGYPGRQGLPGP 746

Query: 146  KGKPGPQG------YPGV-------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGI 192
             G PGP+G       PG+       G+ G+PG+PGK G MGMPG  G  G++G  G  G 
Sbjct: 747  VGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGN 806

Query: 193  PGPQGPPGPHGLPG----------IGKPGGPGLPG------QPGPKGDRGPKGLPGPQGL 236
            PG  G PGP G+PG          IG PG  G+ G      +PG KGD+G +G+PG  G 
Sbjct: 807  PGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGD 866

Query: 237  RGPKGDKGF-GMPGAPGVKGPPG------------MHGPPGPVGLPG------------- 270
             G +GDKG  G+PG PG +G PG              GPPGP G PG             
Sbjct: 867  PGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGM 926

Query: 271  VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGI---PGQ 326
             GKPG  G PGP+G LG  G   + GP GP G PG++G PG  G  G+PG DG+   PG 
Sbjct: 927  KGKPGARGLPGPRGQLGPEG---DEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGD 983

Query: 327  PGFPGGKGEQGL------------------------PGLPGP------PGLPG-IGKPGF 355
            PG PG  GEQG                         PG+PGP      PG+PG +G PG 
Sbjct: 984  PGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGE 1043

Query: 356  PGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE 415
            PGP+G  G  G PG  G +G +GP G  G  G  G  GL G PGP G PG  G  G  GE
Sbjct: 1044 PGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGE 1103

Query: 416  GGIVGPQ---GPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGL 472
             G +G +   G PGP G PG +G PG+P   G  GP G  G PG +GPKG  G  G PGL
Sbjct: 1104 RGHLGSRGFPGIPGPSGPPGTKGLPGEP---GPQGPQGPIGPPGEMGPKGPPGAVGEPGL 1160

Query: 473  PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP----------- 521
            PG  G+ G  G  G PG+QGL G  G PG+ G SGP+GP G+ G +G+P           
Sbjct: 1161 PGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQ 1220

Query: 522  -------GLPGPPGFPGI----------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGP 564
                   G PGPPG  G+          G+ G  G  G  G  G LG  G PG PGPPG 
Sbjct: 1221 EGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGT 1280

Query: 565  PGPPGPPAVMPPTPPP-----QGEYLPDMGLGIDGVK-------PPHAYGAKKGKNG 609
            PGP G    + PT  P     QGE  P +  G DG K       PP   G +KG+ G
Sbjct: 1281 PGPKGSRGSLGPTGAPGRMGAQGE--PGLA-GYDGHKGIVGPLGPPGPKG-EKGEQG 1333



 Score =  409 bits (1050), Expect = e-114
 Identities = 260/585 (44%), Positives = 299/585 (51%), Gaps = 77/585 (13%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPGPQGYP 155
            G   VP    ++ +    G  GP+G  G  G  G PGL G     G+PG+ G PG QG  
Sbjct: 814  GPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDK 873

Query: 156  GV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGP 213
            G  G PG PG  GKPG +G  G KG IG  G  GP G PG  GPPG +G  G+ GKPG  
Sbjct: 874  GSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGAR 933

Query: 214  GLPG---QPGPKGDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLP 269
            GLPG   Q GP+GD GP G PG  GL G  G KGF G PG  GVKG PG  G PGPVG  
Sbjct: 934  GLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQ 993

Query: 270  G-------VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQD 321
            G       VG+PG+ G  G +G +G PG PG  G  G  G+PG  G PG PG  G PG  
Sbjct: 994  GFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSR 1053

Query: 322  GIPGQPGFPGGKG---------EQGLPGLPGPPGLPGIGKPGFPGPKG---------DRG 363
            G PG  G  G +G         EQG  GL GPPG  G  +PG PG +G          RG
Sbjct: 1054 GPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQG--RPGRPGQQGVAGERGHLGSRG 1111

Query: 364  MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG 423
              G+PG  GP G KG  G PG  GP G  G PG  GP GPPGA+G PG  GE G+ G  G
Sbjct: 1112 FPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLG 1171

Query: 424  PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGL------PGPIGPKGEAGQKGV------PG 471
            P G  GE GL G  G+PG  G+ GP G  GL      PGP G  GE GQ+G+      PG
Sbjct: 1172 PLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPG 1231

Query: 472  LPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIG------PPGIPGPKGEPGLPG 525
             PGV G+ GP+G+ G  G++G  G  G  G  G  G +G      PPG PGPKG  G  G
Sbjct: 1232 PPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLG 1291

Query: 526  PPGFPGI----GKPGVAGLH---------GPPGKPGALGPQGQPG-LPGPPGPPGPPGPP 571
            P G PG     G+PG+AG           GPPG  G  G QG+ G   GPPGPPG  GP 
Sbjct: 1292 PTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPV 1351

Query: 572  AVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616
                    P     P    G+ G++       K G+ G P +  P
Sbjct: 1352 GDRGDRGEPGDPGYPGQE-GVQGLR------GKPGQQGQPGHPGP 1389



 Score =  385 bits (990), Expect = e-107
 Identities = 254/621 (40%), Positives = 304/621 (48%), Gaps = 99/621 (15%)

Query: 37   PPQIP--------PQMPPQIPQYQPLGQQVPHMPLAKDGL--AMGKEMPHLQYGKEYPHL 86
            PP +P        P MP  +      G Q P       G+  A G+  P    G + P  
Sbjct: 1019 PPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPR---GPDGPAG 1075

Query: 87   PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIK 146
             Q  + ++  P  G +  P +  +  +A  RG  G RG PG  GP GPPG  G     + 
Sbjct: 1076 EQGSRGLKGPP--GPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKG-----LP 1128

Query: 147  GKPGPQGYPG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLP 205
            G+PGPQG  G +G PG  G  G PGA+G PG  GE G KG++GP+G PG QG  G  G P
Sbjct: 1129 GEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEP 1188

Query: 206  GIGKPGGPGLP-------GQPGPKGDRG------------PKGLPGPQGLRGP------- 239
            G+    GP  P       G PGP G+ G            P G PG  G+RGP       
Sbjct: 1189 GLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQ 1248

Query: 240  --------KGDKGF----------GMPGAPGVKGPPGMHGPPGPVGLPG----VGKPGVT 277
                    KG KG+          G PG PG  GP G  G  GP G PG     G+PG+ 
Sbjct: 1249 GEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLA 1308

Query: 278  GFPGPQG---PLGKPGAPGEPGPQGPIGVPGVQGPPGIPG----IGKPGQDGIPGQPGFP 330
            G+ G +G   PLG PG  GE G QG  G    +GPPG PG    +G  G  G PG PG+P
Sbjct: 1309 GYDGHKGIVGPLGPPGPKGEKGEQGEDGK--AEGPPGPPGDRGPVGDRGDRGEPGDPGYP 1366

Query: 331  GGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG 390
            G +G QGL G PG  G     +PG PGP+G  G  G  GA GP+G++G  GAPG  G  G
Sbjct: 1367 GQEGVQGLRGKPGQQG-----QPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQG 1421

Query: 391  EPGLPG---------IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPG 441
              GLPG         + G  GP G  G  G  G+ G  G  G PGP G  G +G PG  G
Sbjct: 1422 LQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAG 1481

Query: 442  FLGEVGPPGMRG---LPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPG 498
              G  GPPG +G   LPG +GP G+ G +G  GLPG  G  G KG+PG  G+ G  G  G
Sbjct: 1482 LPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAG 1541

Query: 499  IPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL 558
            + G  GP G IG  GI GP+G PGL G  G   +G  G+ G  G PG  G  G +G  GL
Sbjct: 1542 LFGPKGPPGDIGFKGIQGPRGPPGLMGKEGI--VGPLGILGPSGLPGPKGDKGSRGDWGL 1599

Query: 559  PGPPGPPGPPGPPAVMPPTPP 579
             GP GPPGP G P   PP PP
Sbjct: 1600 QGPRGPPGPRGRPG--PPGPP 1618



 Score =  369 bits (946), Expect = e-102
 Identities = 262/663 (39%), Positives = 316/663 (47%), Gaps = 104/663 (15%)

Query: 18   SLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLA--MGKEMP 75
            +LSS      G+    +P    +PP      P+  P    VP    A  G    +G E  
Sbjct: 486  ALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPA---VPTPGSAPTGSKKPIGSEAS 542

Query: 76   HLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGP- 134
                 K  P  P  +       R GK A     +++PL+ L     PR +P P     P 
Sbjct: 543  KKAGPKSSPRKPVPL-------RPGKAA-----RDVPLSDLTTRPSPR-QPQPSQQTTPA 589

Query: 135  --------------PGLPGHGI---------PGIKGKPGPQGYPGVGKPGMPGMPGKPGA 171
                          P   G+ I         P + G PGP+G       G+PG PG PG 
Sbjct: 590  LVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKG-----DCGLPGPPGLPGL 644

Query: 172  MGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLP 231
             G+PGA+G               P+GPPGP+G         PGLPG PG KG +G  GL 
Sbjct: 645  PGIPGARG---------------PRGPPGPYG--------NPGLPGPPGAKGQKGDPGLS 681

Query: 232  GPQGLRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKP 289
              +   G KGD G  G+ G PG  G  G  G PGP G PG  G+PG  G PG +G  G+ 
Sbjct: 682  PGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQ 741

Query: 290  GAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPG------ 343
            G PG  G  GP G  G  G PG+ G+  PG DG  G PG PG +G+ G+PG PG      
Sbjct: 742  GLPGPVGDPGPKGSRGYIGLPGLFGL--PGSDGERGLPGVPGKRGKMGMPGFPGVFGERG 799

Query: 344  PPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 402
            PPGL G  G+ G PGP G  G+ G  G LGP G  GP G  G+ G  GEPGL G  G  G
Sbjct: 800  PPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQG 859

Query: 403  PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKG 462
             PG  G PG +G+ G  G  G PG +G+PG  G  G  G +G  GPPG  G PG IGP G
Sbjct: 860  VPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPG 919

Query: 463  EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG 522
            + G +G+ G PG  GL GP+G+ G  GD+G  GPPG PG+ G  G  G PG PG  G  G
Sbjct: 920  DNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKG 979

Query: 523  LPGPPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGP------PGPPAVM- 574
             PG PG PG +G+ G  G  G  G+PG +G +G  G+ GPPG PGP      PG P  M 
Sbjct: 980  EPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMG 1039

Query: 575  -PPTPPPQGEYLPDMGLGIDGVKPPHAYGAK--KGKNG--GPAYEMPAFTAELTAPFPPV 629
             P  P PQG   P    G     PP   GAK  +G  G  GPA E    +  L  P  P 
Sbjct: 1040 TPGEPGPQG---PPGSRG-----PPGMRGAKGRRGPRGPDGPAGEQG--SRGLKGPPGPQ 1089

Query: 630  GAP 632
            G P
Sbjct: 1090 GRP 1092



 Score =  346 bits (887), Expect = 5e-95
 Identities = 224/504 (44%), Positives = 267/504 (52%), Gaps = 42/504 (8%)

Query: 55   GQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQY--MK-EIQPAPRMGKEAVPKKGKEI 111
            G Q P  P+   G  MG + P    G+  P LP    MK ++ P    G++ +  +  E 
Sbjct: 1132 GPQGPQGPIGPPG-EMGPKGPPGAVGE--PGLPGEAGMKGDLGPLGTPGEQGLIGQRGEP 1188

Query: 112  PLASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKP 169
             L    G  GP G  G RG PGP G  G  G  G+ G+ GP G PGV G  G  G  GK 
Sbjct: 1189 GLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQ 1248

Query: 170  GAMGMPGAKGEIGQKGEIGPMGIPGPQGPPG------------PHGLPG-IGKPGGPGLP 216
            G  G  GAKG  G +G++G MG+PG  GPPG            P G PG +G  G PGL 
Sbjct: 1249 GEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLA 1308

Query: 217  GQPGPKGDRGPKGLPGPQGLRGPKGDKGF--GMPGAPGVKGPPGMHGPPGPVGLPGV-GK 273
            G  G KG  GP G PGP+G +G +G+ G   G PG PG +GP G  G  G  G PG  G+
Sbjct: 1309 GYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQ 1368

Query: 274  PGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGG 332
             GV G  G  G  G+PG PG  G  GP G  G +GP G  G  G PG+ G+ G  G PG 
Sbjct: 1369 EGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGP 1428

Query: 333  KG---EQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGP---RGEKGPIGAPGIG 386
            +G    QGL G+ GP GLPG  + G  G +G++G  G PG +GP   RG  G  G PG  
Sbjct: 1429 RGVVGRQGLEGIAGPDGLPG--RDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQ 1486

Query: 387  GPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEV 446
            GPPG  G  G+PG +GPPG     G +G  G+ G QG PG KG+PG  G  G PG  G  
Sbjct: 1487 GPPGFKGESGLPGQLGPPGK---RGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLF 1543

Query: 447  GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506
            GP   +G PG IG KG  G +G PGL G  G++GP    GI G  GL GP G  G  G  
Sbjct: 1544 GP---KGPPGDIGFKGIQGPRGPPGLMGKEGIVGPL---GILGPSGLPGPKGDKGSRGDW 1597

Query: 507  GPIGPPGIPGPKGEPGLPGPPGFP 530
            G  GP G PGP+G PG PGPPG P
Sbjct: 1598 GLQGPRGPPGPRGRPGPPGPPGGP 1621



 Score =  105 bits (263), Expect = 1e-22
 Identities = 114/389 (29%), Positives = 140/389 (35%), Gaps = 99/389 (25%)

Query: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDR----GMGGVPGALGP 373
           P    +P +   P  K  Q  PG+P PP  P   +P  P     +     +      +  
Sbjct: 409 PTSRPVPARVSRPAEKPIQRNPGMPRPP--PPSTRPLPPTTSSSKKPIPTLARTEAKITS 466

Query: 374 RGEKGPIGAPGIGGPPGEPGLPGIPGP-------------MGPP----------GAIGFP 410
              K          PP    L   P P             M PP           A+  P
Sbjct: 467 HASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTP 526

Query: 411 G--PKGEGGIVGPQG--PPGPKGEPGLQGFPGKPGFLG-EVGPPGMRGLPGPIGPKGE-- 463
           G  P G    +G +     GPK  P  +  P +PG    +V    +   P P  P+    
Sbjct: 527 GSAPTGSKKPIGSEASKKAGPKSSP-RKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQ 585

Query: 464 -----------------------------AGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQ 494
                                        AG    P L G P   GPKG+ G+PG  GL 
Sbjct: 586 TTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPP---GPKGDCGLPGPPGLP 642

Query: 495 GPPGIPGIGGPSGPIGP---PGIPGPKGEPGLPGPPGF-PG---------IGKPGVAGLH 541
           G PGIPG  GP GP GP   PG+PGP G  G  G PG  PG         +G PG++G  
Sbjct: 643 GLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNP 702

Query: 542 GPPGKPGAL---GPQGQPGLPGPPGPPGPPG----------PPAVMPPTPPPQGEYLPDM 588
           GPPG+ G     GP G PG  G PGP G PG          P  V  P P     Y+   
Sbjct: 703 GPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLP 762

Query: 589 GL----GIDGVKPPHAYGAKKGKNGGPAY 613
           GL    G DG +       K+GK G P +
Sbjct: 763 GLFGLPGSDGERGLPGVPGKRGKMGMPGF 791



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 37/104 (35%), Positives = 46/104 (44%), Gaps = 20/104 (19%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGP------RGPPGPPGLPGH-------GIPGIK 146
            G +  P    E+    + G  GP+G PG       +GP GPPGL G        GI G  
Sbjct: 1523 GSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPS 1582

Query: 147  GKPGPQGYPGV-------GKPGMPGMPGKPGAMGMPGAKGEIGQ 183
            G PGP+G  G        G  G PG  G+PG  G PG   ++ Q
Sbjct: 1583 GLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQ 1626



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 60/241 (24%), Positives = 84/241 (34%), Gaps = 33/241 (13%)

Query: 404 PGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGE 463
           P     P  +G  G V P  P  P+     +  P  P     VG P    L   +  K  
Sbjct: 277 PALGSLPAGRGPRGTVAPATPTKPQ-----RTSPTNPHQHMAVGGPAQTPL---LPAKLS 328

Query: 464 AGQKGVPGLPGVPG--LLGPKGEPGIPGDQ--GLQGPPGIPGI-GGPSGPIGPPGIPGP- 517
           A     P LP   G     P+     P  +    + P  +P     PS  I P   P P 
Sbjct: 329 ASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPT 388

Query: 518 -KGEPG------LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGP 570
            K  P       LP     P   +P  A +  P  KP     Q  PG+P PP P   P  
Sbjct: 389 QKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKP----IQRNPGMPRPPPPSTRP-- 442

Query: 571 PAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVG 630
              +PPT     + +P +      +    ++ +K        ++ P FTA  ++P P  G
Sbjct: 443 ---LPPTTSSSKKPIPTLARTEAKIT---SHASKPASARTSTHKPPPFTALSSSPAPTPG 496

Query: 631 A 631
           +
Sbjct: 497 S 497


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  419 bits (1077), Expect = e-117
 Identities = 278/625 (44%), Positives = 315/625 (50%), Gaps = 118/625 (18%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGPRG----EPGPRGPPGPPGLPGH-------GIP 143
            P P+  K  V   G   P    +GE+G  G    EPGP GPPGPPGLPG        G+P
Sbjct: 465  PGPQGIKGKVGPPGGRGP----KGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLP 520

Query: 144  GIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEI------GQKGEIGPMGIPGPQ 196
            G  G  G  G PG  G PG+PG  G  G  G  GAKG++      G KGE GP G PG  
Sbjct: 521  GWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFP 580

Query: 197  GPPGPHGLPG---------------IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKG 241
            G PG HG  G                  PGG G PG  GP G  GP G PG  G  GP G
Sbjct: 581  GQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPG-LGFPGPPG 639

Query: 242  DKGF-GMPGAPGVKGPPGMHGP-----------PGPVGLPGV-GKPGVTGFPGPQGPLGK 288
            ++G  G+PG PGV+GP G+ G            PG  G PG  G PG  GFPGPQG  G 
Sbjct: 640  ERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGL 699

Query: 289  PGAPGEPGPQGPIGVPGVQGPPGIPG-IGKPG--------QDGIPGQPGFPGGKGEQGLP 339
             G+ G  G  G  G   + GPPG  G +G PG          G PG PG PG  G++G+P
Sbjct: 700  SGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIP 759

Query: 340  GLP-----GPPGLPGI-GKPGFPGPKGD------RGMGGVPGAL---GPRGEKGPIGAPG 384
            G P     GPPG  G+ G PG  GP+GD       G  G+PG L   GP+G +G  G PG
Sbjct: 760  GDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPG 819

Query: 385  IGGPPGE------PGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP- 437
            + GPPG       PG+PG PG  G PG+ G PG KG+ G VGP GP G KG PGL G P 
Sbjct: 820  VPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPG 879

Query: 438  --GKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGI---PGDQG 492
              G PG  G  GP G  GLPGP GPKG  G  G PG PG  G  G +G PG    PG++G
Sbjct: 880  AHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKG 939

Query: 493  LQGPPGIPGIGGPSGPIGPPGIPG------PKGEPGLPGPP---GFPG-IGKPGVAGLHG 542
            + G PG  G+ G  G IGPPG  G       KG PG PGPP   GFPG  G  G  G+ G
Sbjct: 940  MSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQG 999

Query: 543  PPGKPGALGP----QGQPGLPGPPGPPGPPGPPAV--------MPPTPPPQGE---YLPD 587
              G+PG  GP    +G+PG  G PGPPGPPGPP           P  P  QGE     P 
Sbjct: 1000 RRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPP 1059

Query: 588  MGLGIDGVKPPHAYGAKKGKNGGPA 612
               GIDG + P      KG  G PA
Sbjct: 1060 GFSGIDGARGP------KGNKGDPA 1078



 Score =  416 bits (1070), Expect = e-116
 Identities = 266/606 (43%), Positives = 308/606 (50%), Gaps = 98/606 (16%)

Query: 91   KEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPG 150
            K I   P  G    P K     +  ++G +G  G PG  GP G PG    G+ G KG+ G
Sbjct: 756  KGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGF--LGLKGPKGREG 813

Query: 151  PQGYPGV----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPG 200
              G+PGV          G PG+PG PG PG  G PGA G  GQ G++GP   PGP G  G
Sbjct: 814  HAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGP---PGPAGMKG 870

Query: 201  PHGLPG-IGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGM 259
              GLPG  G  G PGLPG PGP GD    GLPGP G +GP+G  GF  PG PG +G PG 
Sbjct: 871  LPGLPGRPGAHGPPGLPGIPGPFGD---DGLPGPPGPKGPRGLPGF--PGFPGERGKPGA 925

Query: 260  HGPPGPVGLPG----VGKPGVTGFPGPQGPLGKP------------GAPGEPGPQGPIGV 303
             G PG  G PG     G PG  G  G +G +G P            G PGEPGP G  G 
Sbjct: 926  EGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGF 985

Query: 304  PGVQGPPGIPGI-GKPGQDGIPGQPGFPGGK-GEQGLPGLPGPPGLPG-------IGKPG 354
            PG +G  G PG+ G+ G+ G  G PGF  G+ GE+G PG PGPPG PG       IG PG
Sbjct: 986  PGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPG 1045

Query: 355  FPGPKGD------RGMGGVPGALGPRGEKG-PIGAPGIGGPPGEPGLPGIPGPMGPPGAI 407
             PG +G+       G  G+ GA GP+G KG P    G  GP GEPG PG PG  G  G  
Sbjct: 1046 LPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQ 1105

Query: 408  GFP---GPKGEGGIVGP---QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK 461
            G P   GP+G  G  GP    GPPG  G+ G+ G  G+PG +G+ GP G++G PG  GP 
Sbjct: 1106 GLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPP 1165

Query: 462  GEAGQKGVPGLPGVPGLLGPKGEPGIPG--DQGLQGPPGIPGIGGPSGPIGPPGI--PGP 517
            G  G  G PGL G+ GL G KG  G  G  D G  GP GIPG+ G  G  G PGI  PGP
Sbjct: 1166 GIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGP 1225

Query: 518  KGEPGLPGPPG-----------------FPGIGKPGVAGLHGPPGKPGALGPQGQP---- 556
            +G+ G PGPPG                  P  G PG  G  GP G  GA GP G P    
Sbjct: 1226 RGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVD 1285

Query: 557  ---------GLPGPPGPPGPPGPPAV--MPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKK 605
                     GLPGPPGPPGPPGPP     P      G+  P   +G  G + PH +    
Sbjct: 1286 LLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGP---VGFPGPQGPHGFPGPP 1342

Query: 606  GKNGGP 611
            G+ G P
Sbjct: 1343 GEKGLP 1348



 Score =  410 bits (1053), Expect = e-114
 Identities = 276/651 (42%), Positives = 312/651 (47%), Gaps = 136/651 (20%)

Query: 38   PQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAP 97
            P IP Q  P +P Y       P  P    G   GK  P    G   P  P  MK +   P
Sbjct: 833  PGIPGQ--PGLPGY-------PGSP----GAPGGKGQP----GDVGPPGPAGMKGLPGLP 875

Query: 98   -RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYP 155
             R G    P       L  + G  G  G PGP GP GP GLPG  G PG +GKPG +G P
Sbjct: 876  GRPGAHGPPG------LPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929

Query: 156  GV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPM------GIPGPQGPPGPHGLPGI- 207
            G  G+PG  GM G PG  G+ GAKG IG  G+ G M      G PG  GPPG  G PG  
Sbjct: 930  GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989

Query: 208  GKPGGPGL------PGQPGP----KGDRGPKGLPGPQGLRGPKGDKGF----GMPGAPGV 253
            G  G PG+      PG+ GP    +G+ G KG PGP G  GP G  G     G PG PG 
Sbjct: 990  GDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGD 1049

Query: 254  KGPPGMHGPPGPVGLPGV-GKPGVTGFP----GPQGPLGKPGAPGEPG---PQGPIGVPG 305
            +G PG  GPPG  G+ G  G  G  G P    GP GP G+PG+PG PG     G  G+PG
Sbjct: 1050 QGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPG 1109

Query: 306  VQGPPGIPGI----------------GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG 349
            +QGP G PG                 G PG  G PG+ G PG +G QG PG+PGPPG+ G
Sbjct: 1110 IQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKG 1169

Query: 350  -IGKPGFPGPKGDRGMGGVPGALGPR--GEKGPIGAPGIGGPPGEPGLPGIP-------- 398
              G PG  G  G +G  G  GA G    G  GP+G PG+ G  G+PG PGI         
Sbjct: 1170 PSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKK 1229

Query: 399  GPMGPPGAIGFPGPKG----------EGGIVGPQGPPGPKGEPGLQGFPGKPGFL----G 444
            GP GPPG+ G PGP G          + G  G QGPPGP G  G  G PG PG +    G
Sbjct: 1230 GPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRG 1289

Query: 445  EVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG 504
            E G  G+ G PGP GP G  G KG PG  G  G  GP G PG  G  G  GPPG  G+ G
Sbjct: 1290 EPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPG 1349

Query: 505  PSGPIGPPGIPGPKGEPG----------LPGPPGFPGI---------------------- 532
            P G  GP G+PGP+GEPG          +PG PG PG+                      
Sbjct: 1350 PPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKG 1409

Query: 533  --------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575
                    G  GV G  GPPG+ G  G  G PG PGPPGP G PGP    P
Sbjct: 1410 EPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGP 1460



 Score =  392 bits (1008), Expect = e-109
 Identities = 265/670 (39%), Positives = 307/670 (45%), Gaps = 176/670 (26%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV----GKPGMPGMPGKPGAM 172
           +GE+G +G PG  G PGPPG  G    G KG+ G  G+PG     G  G PG PG  G +
Sbjct: 269 KGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGEL 328

Query: 173 GM---PGAKGEIGQKGEIGPMGIPGP-----------QGPPGPHGLPG-------IGKPG 211
           G+   PG  G IG KG+ G  G PGP           +GPPG  G PG       +G PG
Sbjct: 329 GLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPG 388

Query: 212 GPGLPGQPGPK-----GDRGPKGLPGPQGLRGPKGDKG--FGMPGAPGVKGPPGMHGPPG 264
            PGL G+PG       G  GP+G PG  GL G  G  G     PG PG  G PG+ G PG
Sbjct: 389 PPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPG 448

Query: 265 PVGLPG-------VGKPGVTGF-------------------------PGPQGPLGKPGAP 292
             GLPG       VG PG  G                          PGP GP G PG P
Sbjct: 449 LQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLP 508

Query: 293 GEPGPQGPIGVP---GVQGPPGIPGI----GKPGQDGIPGQPGFPGGKGE---------Q 336
           G  G +G +G+P   G +G PG PG     G PG+ G  G PG  G KG+         +
Sbjct: 509 GRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHK 568

Query: 337 GLPGLPGPPGLPG----------IGKPGFPGPKGDR-----GMGGVPGALGPRGEKGPIG 381
           G  G  GPPG PG           G+ G PGP GD      G  G PG LGP G+ GP+G
Sbjct: 569 GERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVG 628

Query: 382 APGIG--GPPGEPGLPGIPGPM--------------------------------GPPGAI 407
            PG+G  GPPGE G PG+PG                                  GPPG  
Sbjct: 629 PPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPK 688

Query: 408 GFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMR--------GLPGPIG 459
           GFPGP+G  G+ G  G  G  G PG    PG PGF G++G PG          G PGP G
Sbjct: 689 GFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPG 748

Query: 460 PKGEAGQKGVP--------------GLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGP 505
             G  GQKG+P              GL GVPG+ GP+G+PG PG +G  G PG  G+ GP
Sbjct: 749 SPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGP 808

Query: 506 ---SGPIGPPGIPGP------KGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQ 555
               G  G PG+PGP      +G PG+PG PG PG  G PG  G  G PG  G  GP G 
Sbjct: 809 KGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGM 868

Query: 556 PGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEM 615
            GLPG PG PG  GPP  +P  P P G+         DG+  P      KG  G P +  
Sbjct: 869 KGLPGLPGRPGAHGPPG-LPGIPGPFGD---------DGLPGP---PGPKGPRGLPGF-- 913

Query: 616 PAFTAELTAP 625
           P F  E   P
Sbjct: 914 PGFPGERGKP 923



 Score =  378 bits (970), Expect = e-104
 Identities = 267/712 (37%), Positives = 314/712 (44%), Gaps = 217/712 (30%)

Query: 116 LRGEQGPRGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPGV-------GKPGMPG 164
           +RG++GP G  G +G  GP G+PG     GIPG  G PGP+G PG+       G PG PG
Sbjct: 93  MRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPG 152

Query: 165 -----------------------------------------MPGKPGAMGMPGAKGEIGQ 183
                                                    +PG PG+ G  G  G  G 
Sbjct: 153 GRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGY 212

Query: 184 KGEIGPMGIPGPQGPPGPHGLPGI------GKPGGPGLPGQPGP------------KGDR 225
            GE G +G PG  G PG  G PG+      G PG  G  G PGP            KG++
Sbjct: 213 PGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEK 272

Query: 226 GPKGLPGPQGLRGPKGDKG------------------------FGMPGAPGVK------- 254
           G KG+PG  GL GP G KG                        +G PG PG+K       
Sbjct: 273 GIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVG 332

Query: 255 --------------------GPPG--------MHGPPGPVGLPG-VGKPGVTGFPGPQGP 285
                               GPPG        + GPPG  G PG  G+ G  G PGP G 
Sbjct: 333 DPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGL 392

Query: 286 LGKPGAP-----GEPGPQGPIGVPGVQGPPGIPG--IGKPGQDGIPGQPGFPGGKGEQGL 338
           LG+PG       G PGPQG  G+PG+ G  GIPG     PG+ G PG PG PG  G QGL
Sbjct: 393 LGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGL 452

Query: 339 PGL---------PGPPGLPG-IGKPGFPGPKGDRGMGGV----PGALGP---------RG 375
           PG          PGP G+ G +G PG  GPKG++G  G+    PG +GP         +G
Sbjct: 453 PGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQG 512

Query: 376 EKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGP---------------KGEGGIVG 420
            KG +G PG  G  G+PG PG  GP G PG  G  GP               KG  G  G
Sbjct: 513 SKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERG 572

Query: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGP--------PGMRGLPGPIGPKGEAGQKGVPGL 472
           P GPPG  G+PG  G  G  G  G+ GP        PG +G PGP+GP G+AG  G PGL
Sbjct: 573 PDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL 632

Query: 473 PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS--------GPIGPPGIPGPKGEPGLP 524
            G PG  G +G PG+PG  G++GP G+ G  G +        G  GPPG  GP G  G P
Sbjct: 633 -GFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFP 691

Query: 525 GPPGFPGI-------GKPGVAGLHGPPGKPGALGPQGQPGLPG-----PPGPPGPPGPPA 572
           GP G PG+       G+PG  G    PG PG  G  G PG  G     P GPPGPPG P 
Sbjct: 692 GPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPG 751

Query: 573 VMP----PTPPPQGEYLP--DMGL-GIDGVKPPHAYGAKKGKNGGPAYEMPA 617
           V      P  P  G   P    GL G+ G+K P      +G  G P  E PA
Sbjct: 752 VNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGP------RGDPGCPGAEGPA 797



 Score =  368 bits (945), Expect = e-101
 Identities = 257/600 (42%), Positives = 296/600 (49%), Gaps = 81/600 (13%)

Query: 100 GKEAV-PKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVG 158
           GK+ + P  G++  +     E+G RG PGP GP GP G          G PGP G  G  
Sbjct: 40  GKKYIGPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGP--------LGAPGPIGLSG-- 89

Query: 159 KPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPG 217
           + GM G  G PGA G  G KG  G  G  G  GIPG  GPPGP G PG+ G  G  G PG
Sbjct: 90  EKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPG 149

Query: 218 QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKP-GV 276
            PG +G  GP G  G  G +G KG+  F +    G++G  G  G PG  G  G G P G 
Sbjct: 150 FPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGP 209

Query: 277 TGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPG------QPGFP 330
           TG+PG  G +G PG PG PG +G  GV GV+G  G P  G+ GQ G PG       P F 
Sbjct: 210 TGYPGEPGLVGPPGQPGRPGLKGNPGV-GVKGQMGDP--GEVGQQGSPGPTLLVEPPDFC 266

Query: 331 GGKGEQGLPGLPGPPGLPG---------------IGKPGFPGPKGDRGMGGVPGALGPRG 375
             KGE+G+ G+PG  GLPG                G PGFPGP+GD G  G PG  G +G
Sbjct: 267 LYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKG 326

Query: 376 EKGPIGAPGIG---GPPGEPGLPGIPGP-----------MGPPGAIGFPGPKGEGGIVGP 421
           E G +G PG+    GP G+PG  G PGP            GPPG  GFPG  GE G VGP
Sbjct: 327 ELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGP 386

Query: 422 QGPPGPKGEP-----GLQGFPGKPGFLGEVGPPGMRGLPG-PIGPKGEAGQKGVPGLPGV 475
            GPPG  G P     G+ G PG  GF G  G PG  G+PG P    G+ G+ G PGLPG 
Sbjct: 387 PGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGA 446

Query: 476 PGLLGPKGEP------GIPGDQGLQGPPGIPGIGGPSGPIGPPGI----PGPKGEPGLPG 525
           PGL G  G        G PG QG++G  G PG  GP G  G  G+    PGP G PG PG
Sbjct: 447 PGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPG 506

Query: 526 PPGFPG----IGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPA--VMPPTPP 579
            PG  G    +G PG  G  G PG PGA GP G PG  G  GPPG  G     V+     
Sbjct: 507 LPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKG 566

Query: 580 PQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAP----FP-PVGAPVK 634
            +GE  PD   G  G    H      G+ G P    P    E   P    FP P+G P K
Sbjct: 567 HKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPG---PPGDHEDATPGGKGFPGPLGPPGK 623



 Score =  206 bits (524), Expect = 6e-53
 Identities = 153/387 (39%), Positives = 172/387 (44%), Gaps = 92/387 (23%)

Query: 333 KGEQGLPGLPGPPGLPG-IGKPG---FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGP 388
           KG +G PG PGP G  G +G PG     G KG RG  G PGA G +G+KGP G PG    
Sbjct: 61  KGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGF--- 117

Query: 389 PGEPGLPGIPGPMGPPGA---------------IGFPGPKGEGGIVGPQGPPGPKGE--- 430
              PGL GIPG  GPPG                 GFPG +G  G  GP G PG KGE   
Sbjct: 118 ---PGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGN 174

Query: 431 -----------------PGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP 473
                            PGL G PG  G  G  GP G  G PG +GP G+ G+ G+ G P
Sbjct: 175 SVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNP 234

Query: 474 GV--------PGLLGPKGEP---------------------GIPGDQGLQGPPGIPGIG- 503
           GV        PG +G +G P                     GIPG  GL GPPG  G   
Sbjct: 235 GVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG 294

Query: 504 -GPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPP 562
            G  G  G PG PGP+G+PG  G PGFPG+   G  GL G PG  G +GP+G PG  G P
Sbjct: 295 IGAKGEKGIPGFPGPRGDPGSYGSPGFPGL--KGELGLVGDPGLFGLIGPKGDPGNRGHP 352

Query: 563 GPPG----PPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYG----AKKGKNGGPAYE 614
           GPPG    PP P    P  P   G Y     +G  G  PP   G    A  G  G P  +
Sbjct: 353 GPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPG--PPGLLGRPGEACAGMIGPPGPQ 410

Query: 615 ----MPAFTAELTAPFPPVGAPVKFNK 637
               +P    E   P  P  AP K  K
Sbjct: 411 GFPGLPGLPGEAGIPGRPDSAPGKPGK 437


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  419 bits (1076), Expect = e-117
 Identities = 261/578 (45%), Positives = 302/578 (52%), Gaps = 92/578 (15%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175
            G++G  G PG  GPPG  G+ G  G PG  G PGP G PG  G+ G PG+PG  G  G P
Sbjct: 871  GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930

Query: 176  GAKGEIGQKGEIGPM------------------GIPGPQGPPGPHGLPGI-GKPGGPGLP 216
            GAKGE G KG  GP                   G PG +G  G  G+PG+ G  G PG  
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 217  GQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGV---- 271
            G PGP+GD G  G PG  GLRG  G  G  GMPG+ G +G  G  G  G  GLPG+    
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 272  --------------GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-G 316
                          G PG TG PG  G +GK G  G+PGP G +G  G +G PG PG  G
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 317  KPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGP---KGDRGMGGVPGALGP 373
             PG+ G  G  GF G KG  G PG+ GPPGLPG   PG PGP   +GD+G  G+PG  G 
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGF--PGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 374  RGEKGPIGAP----------GIGGPPGEPGLPGIPG---------PMGPPGAIGFPGPKG 414
            +GE G + AP          G  G  G PG PG+PG         P GP G  GFPGP G
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 415  EGGIV-----GPQGPPGPKGEPGLQGFPGKPG--FLGEVGPPGMRGLPGPIGPKGEAGQK 467
              G +     G +GPPG +G PG  G PG PG   +G  G  G  G PGP GP G AG  
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDM 1288

Query: 468  GVPG---LPGVPGLLGPKGEPGI---PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP 521
            G PG    PG PGL GP+G+PG    PG +G +G PG  G  GP GPIGP G PG +G+P
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348

Query: 522  G------LPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVM 574
            G      LPG PG PG  G+PG+ G  GPPG PG LGP G  G PG  G PG PG PA  
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPG-PAGE 1407

Query: 575  PPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPA 612
                  +GE  P    G+ G+K       K+G +G PA
Sbjct: 1408 KGNKGSKGEPGPAGSDGLPGLK------GKRGDSGSPA 1439



 Score =  406 bits (1044), Expect = e-113
 Identities = 267/635 (42%), Positives = 300/635 (47%), Gaps = 142/635 (22%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175
           +G  GP G PGP+GP G PGLPG  + G KG  G  G PG  G PG+PG PG  G  G+ 
Sbjct: 63  KGFTGPEGLPGPQGPKGFPGLPG--LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLV 120

Query: 176 GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKP-----------GGPGLPGQPG 220
           G  G  G KGE G  G+PG  G PG  G  G+    G P           G PGLPG PG
Sbjct: 121 GVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPG 180

Query: 221 PKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPG-----------------MHGPP 263
           P+G  GP G PGP G  GP G   FG PGA G +GP G                 + GPP
Sbjct: 181 PQGLPGPPGFPGPVGPPGPPGF--FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 238

Query: 264 GPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG-----VQGPPGIPGI-GK 317
           GP G   V   G       +G  G  GA GEPGP GP G+PG      +G PG PG+ GK
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGK 298

Query: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG----IGKPGFPGP---------KGDRGM 364
           PG+DG+PG PG  G KG +G PGL G  G+ G    IG PGF GP         KGD G 
Sbjct: 299 PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 365 GGVPGALGPRGEKGPIGAPGIGGPP----------------------------------- 389
            G PG  G RG +GP G PG+ G P                                   
Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 390 -----GEPGLPGIPGPMGPPGAIGF-PGPKGEGGIVGPQGPP------GPKGEPGL---- 433
                G PGLPG PGP GPPG I F  GP G+ G+ G  G P      GPKGEPGL    
Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 434 -------QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG------ 480
                   G PG PG  G  G PG +G  G  G  G  G  G+PG PG PG  G      
Sbjct: 479 CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 481 -------PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPK------GEPGLPGPP 527
                  P+G+ G+PGD GL+G PG  G+ G  G  G  G+PGPK      GE G  GPP
Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 528 GFPGI-GKPGVAGLHGPP-----GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQ 581
           G PG  G PG AG  GPP     G+PG  G QG PG PGPPG  GP G  +V  P P P 
Sbjct: 599 GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 582 GEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616
           G   P    G  G + P       GK G P    P
Sbjct: 659 G---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGP 690



 Score =  404 bits (1039), Expect = e-112
 Identities = 272/693 (39%), Positives = 307/693 (44%), Gaps = 203/693 (29%)

Query: 118  GEQGPRGE-------PGPRGPPGPPGLPGH----GIPGIKGK------PGPQGYPGVGKP 160
            GE GPRGE       PGP GPPGPPG PG     GIPG  GK      PGP G PG+   
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 161  GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPG 220
            G PG PG  G  G PG KG +G  G++G  G+PG  G PG  G P +  PGGPG PG PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 221  PKGDRGPKG------------LPGPQGLRGPKGDKGFGMPGAPGVKGPPG--MHGPPGPV 266
             +G+ G  G             PG +GL GP+GD G   PG PG +GPPG  + GP G  
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG--QPGPPGEQGPPGRCIEGPRGAQ 817

Query: 267  GLPGV---------------------------------GKPGVTGFPGPQGPLGKPGAPG 293
            GLPG+                                 G PG+ G  G  GPLG+ G PG
Sbjct: 818  GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG 877

Query: 294  EPGPQGP---------IGVPGVQGPPGIPGI-------GKPGQDGIPGQPGFPGGKGEQG 337
             PG  GP         +G PG  GPPG PG        G PG  G+ GQ G PG KGEQG
Sbjct: 878  NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQG 937

Query: 338  LPGLPGPP---------GLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAP---- 383
              G PGP          G PG+ G  G PG KG+RG+ G+PG  G +G  GP G P    
Sbjct: 938  DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRG 997

Query: 384  --GIGGPPGEPGLPGIPGPMG---------PPGAIGFPGPKGEGGIVGPQG--------- 423
              G  G PGEPGL GIPG MG           G +GFPG  G  G+ G  G         
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057

Query: 424  --------PPGPKGEPGL---------QGFPGKPGFLGEVGP------PGMRGLPGPIGP 460
                    PPGP G+PGL          G PG PG LG  GP      PG  GLPG  GP
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117

Query: 461  KGEAGQKGVPGLPGVPGLLGPKGEPGIPG---------DQGL------------------ 493
             G+ G KG+ GL G PG+ GP G PG PG         DQG                   
Sbjct: 1118 HGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA 1177

Query: 494  ----------------QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGV 537
                            +G PG PG+ G  G +G  G  GP G  G PGPPG PG   PG 
Sbjct: 1178 PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQ 1237

Query: 538  AGLHGPP---GKPGALGPQGQPGL--------PGPPGPPGPPGPPAVMPPTPPPQGEYLP 586
             G  GPP   G PGA GP G PG          G  G PGP GPP       PP     P
Sbjct: 1238 TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297

Query: 587  DMGLGIDGVKPP------HAYGAKKGKNGGPAY 613
                G  G+  P        +   KG+ G P +
Sbjct: 1298 ----GTPGLPGPRGDPGFQGFPGVKGEKGNPGF 1326



 Score =  399 bits (1025), Expect = e-111
 Identities = 263/640 (41%), Positives = 310/640 (48%), Gaps = 123/640 (19%)

Query: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157
            R G + +P       L   +GE    GE G +GPPG PG PG   PG  G  GP GY   
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS--PGPAGPAGPPGYGPQ 621

Query: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKGEI-------GPMGIPGPQGPPGPHGLPGI--- 207
            G+PG+ G  G PGA   PG  GE G +GE+       GP G PGP G PGP G PGI   
Sbjct: 622  GEPGLQGTQGVPGA---PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGS 678

Query: 208  -------------GKPGGPGL--PGQPGPKGDRG---------------PKGLPGPQGLR 237
                         G+PG PG+  PG PGPKGD+G                 GLPG  GL 
Sbjct: 679  LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLP 738

Query: 238  GPKGDKGFGMPGAPGVKGPPGMHGPPGP---VGLPGVGKPGVTGFPGPQGPLGKPGAPGE 294
            G KG+    MPG PG  G PG  G  G    +GLPG+  PG+ G PG +G  G  G PG+
Sbjct: 739  GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL--PGLPGTPGNEGLDGPRGDPGQ 796

Query: 295  PGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPG 354
            PGP      PG QGPPG    G  G  G+PG  G  G +G +G  G  G PG+PG+ + G
Sbjct: 797  PGP------PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 355  FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKG 414
            FPG  G  G+ G  G +GP G++G  G PGI GPPGE G+ G+   MG PGAIG PGP G
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGM---MGFPGAIGPPGPPG 907

Query: 415  EGGIVGPQGPP---------------------------------GPKGEPGLQGFPGKPG 441
              G  G +G P                                 G KGEPGL+GF G PG
Sbjct: 908  NPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967

Query: 442  FLGEVGPPGM------RGLPGPI---GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQG 492
              G  G PGM      +GLPGP    GP+G+ G  G PG PG+ G+ G  G  G+PG +G
Sbjct: 968  EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027

Query: 493  LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGL--------PGPPGFPGI----GKPGVAGL 540
             +G  G PG  G  G  G  G+ G KGEPG         PGP G PG+    GK G  G 
Sbjct: 1028 KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ 1087

Query: 541  HGPPGKPGALGPQGQPGLPGPPGPPGPPGP------PAVMPPTPPPQGEYLPDMGLGIDG 594
             GPPG  G  GP+G PG PG PG PG PGP        +     PP     P +  G  G
Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLP-GFPG 1146

Query: 595  VKPPHAYGAKKGKNG--GPAYEMPAFTAELTAPFPPVGAP 632
               P      +G++G  GPA E    T  L AP  P G P
Sbjct: 1147 SPGPMGIRGDQGRDGIPGPAGE-KGETGLLRAPPGPRGNP 1185



 Score =  393 bits (1009), Expect = e-109
 Identities = 269/662 (40%), Positives = 322/662 (48%), Gaps = 89/662 (13%)

Query: 35   PLPPQIP-PQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEI 93
            P PP  P PQ PP IP             L K G       P L      P +P      
Sbjct: 661  PGPPGHPGPQGPPGIPG-----------SLGKCG------DPGLPGPDGEPGIPGIGFPG 703

Query: 94   QPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQG 153
             P P+ G +  P     +      GE G  G+PG  G  G P +   G PG  G PG +G
Sbjct: 704  PPGPK-GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762

Query: 154  YPG----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP--QGPPGPHGLPGI 207
              G    +G PG+PG+PG PG  G+ G +G+ GQ G  G  G PG   +GP G  GLPG+
Sbjct: 763  NSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL 822

Query: 208  -------------GKPGGPGLPG--QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG 252
                         G  G PG+PG  + G  G+ G  G+PG QG  GP G +G+  PG PG
Sbjct: 823  NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY--PGNPG 880

Query: 253  VKGPPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311
            + GPPG  G  G +G PG +G PG  G PG  G  G PG PG  G +G  G  G QG  G
Sbjct: 881  ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 312  IPG-------IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRG 363
             PG       IG  G+ G+ G  G PG KG +G+PG+PG  GL G+ G  G PGP+GD G
Sbjct: 941  NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG 1000

Query: 364  MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG--- 420
              G PG  G RG  G +G  G+ G  G+ G  G PG  G PG  G  G +G+ G  G   
Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSE 1060

Query: 421  --PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGL 478
                GPPGP G+PGL G  GK G +G+ GPPG  G  GP G  G  G  G+PG PG  G 
Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD 1120

Query: 479  LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPI------GPPGIPGP---KGEPGL----PG 525
            LG KG  G+ G  G++GPPG+PG  G  GP+      G  GIPGP   KGE GL    PG
Sbjct: 1121 LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180

Query: 526  PPGFPGI-------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTP 578
            P G PG        G PG  GL G  G  G  GP+G  G+ G PGPPG PG  A++P   
Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG--AIIPGQT 1238

Query: 579  PPQGEYLPDMGLGIDGVKPP------HAYGAK--KGKNGGPAYEMPAFTAELTAPFPPVG 630
              +G   P    G  G   P      H  G K  KG  G P  + P  TA    P   +G
Sbjct: 1239 GNRG---PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 631  AP 632
            AP
Sbjct: 1296 AP 1297



 Score =  374 bits (959), Expect = e-103
 Identities = 226/494 (45%), Positives = 255/494 (51%), Gaps = 80/494 (16%)

Query: 113  LASLRGEQGPRGEPGPRGP------PGPPGLPG-------HGIPGIKGKPGPQGYPG-VG 158
            L  L+G  GP G PGPRG       PG PGL G        G+PG KGK G  G+PG  G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 159  KPGMPGM-----------------PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGP 201
            +PG+PG+                 PG PG  G PG  G++G+KGE+G  G PG  GP GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 202  HGLPGIGKPGGPGLPGQPGPKGD---RGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPP 257
             G PG   PG PGLPG+PGP GD   +G KGL GP G+RGP G  GF G PG  G++G  
Sbjct: 1100 EGAPG--SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQ 1157

Query: 258  GMHGPPGPVGLPGV-----GKPGVTGFPGPQGPLGKPGAPGEPG------------PQGP 300
            G  G PGP G  G        PG  G PG QG  G  GAPG PG            P+GP
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217

Query: 301  IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360
             G+ G  GPPG+PG   PGQ G  G PG       +G PG PGPPG PG    G    KG
Sbjct: 1218 TGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSHVIGI---KG 1268

Query: 361  DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420
            D+G  G PG  GP G  G +G PG  G PG PGL   PGP G PG  GFPG KGE     
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL---PGPRGDPGFQGFPGVKGE----- 1320

Query: 421  PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
                   KG PG  G  G PG +G  GPPG+RG PG +      G  G PG PG PG+ G
Sbjct: 1321 -------KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 481  PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540
              G PG PG+ G  GP G PG  G  G  GP G  G KG  G PGP G  G+  PG+ G 
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL--PGLKGK 1431

Query: 541  HGPPGKPGALGPQG 554
             G  G P     +G
Sbjct: 1432 RGDSGSPATWTTRG 1445



 Score =  268 bits (684), Expect = 2e-71
 Identities = 168/397 (42%), Positives = 194/397 (48%), Gaps = 60/397 (15%)

Query: 87   PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIK 146
            P Y +  +P P  G    P    ++      G+ GP G  GP GP G PG PG   PG+ 
Sbjct: 1056 PGYSEGTRPGPP-GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS--PGLP 1112

Query: 147  GKPGPQG---YPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG----- 197
            GKPGP G   + G+ G  G PG+ G PG  G PG+ G +G +G+ G  GIPGP G     
Sbjct: 1113 GKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172

Query: 198  -----PPGPHGLPGI-------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF 245
                 PPGP G PG        G PG PGLPG+ G  GD GP+G  G +G  GP G  G 
Sbjct: 1173 GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232

Query: 246  GMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305
             +PG  G +GPPG  G PG  G PG     V G  G +G +G PG  G PG  G +G PG
Sbjct: 1233 IIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 306  VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPG---------PPGLPGI------ 350
              G PG PG+  PG  G PG  GFPG KGE+G PG  G         P G PG+      
Sbjct: 1293 RLGAPGTPGL--PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 351  -------GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA---PGIGGPPGEPGLPGIPGP 400
                   G PG PG  G+ GM G PG  GP G  GP G    PG  G PG P        
Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTP-------- 1402

Query: 401  MGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP 437
             GP G  G  G KGE G  G  G PG KG+ G  G P
Sbjct: 1403 -GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score =  196 bits (497), Expect = 9e-50
 Identities = 132/313 (42%), Positives = 149/313 (47%), Gaps = 50/313 (15%)

Query: 325 GQPGFPGGKGEQGLPGLPGPPGLPG----IGKPGFPGPKGDRGMGGVPGALGPRGEKGPI 380
           GQ    G KGE+G  G PGPPG PG     G  G PGP+G +G  G+PG  G +G +G  
Sbjct: 37  GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 381 GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP 440
           G PG  G    PGLPG PG  GP G +G PG  G             KGE   QGFPG P
Sbjct: 97  GLPGFSG---SPGLPGTPGNTGPYGLVGVPGCSGS------------KGE---QGFPGLP 138

Query: 441 GFLGEVGPPGMRGLPGPIGPKG-----EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQG 495
           G LG  G PG  GL G  G        E   KG PGLPG PG  G  G PG PG  G  G
Sbjct: 139 GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG 198

Query: 496 PPGIPGIGGPSGPIGPPG-----IPGPKGE---PGLPGPPGFPGIGKPGVAGLHGPPGKP 547
           PPG  G  G  GP GP G     + G KGE    GL GPPG PG     +  L GP  + 
Sbjct: 199 PPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG---TVIVTLTGPDNRT 255

Query: 548 GALGPQGQPGLPGPPGPPGPPGPPAV-------MPPTPPPQGEYLPDMGL----GIDGVK 596
              G +G  G  G PGPPGP G P          P  P  QG+   D G+    G +GVK
Sbjct: 256 DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKD-GVPGFPGSEGVK 314

Query: 597 PPHAYGAKKGKNG 609
               +    G++G
Sbjct: 315 GNRGFPGLMGEDG 327



 Score =  187 bits (475), Expect = 3e-47
 Identities = 115/267 (43%), Positives = 134/267 (50%), Gaps = 18/267 (6%)

Query: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420
           D+G     GA G +GEKG  G PG  G  G  G  G+PGP GP G  G PG  G  G+ G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
             G PG  G PGL G PG  G  G VG PG  G  G  G  G  G  G PG+PG  GL G
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 481 PKGEPGIPGDQGL--QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVA 538
            KG P    D  L  +G PG+PG  GP G  GPPG PGP G    PGPPGF   G PG  
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGF--FGFPGAM 209

Query: 539 GLHGPPGKPG--ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMG----LGI 592
           G  GP G  G   +G +G+ G+ G  GPPGPPG   V    P  + +   + G    +G 
Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 593 DGVK-----PPHAYGAKKGKNGGPAYE 614
            G       P  +YG++KG  G P  +
Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQ 296



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 69/196 (35%), Positives = 85/196 (43%), Gaps = 60/196 (30%)

Query: 116  LRGEQGPRGEPGPRGPPG------PPGLPGH----GIPGIKGKPGPQGYPGV-------- 157
            ++G++G  G PGP+GPPG      PPG  G     G+PG +G PG QG+PGV        
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 158  --------------GKPGMPGMPGK------PGAMGMPGAKGEIGQKGEIGPMGIPGPQG 197
                          G PG+ G PG       PG+ G PG  GE G +GE GP G PG  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 198  PPGPHGLPGI-GKPGGPG---------------------LPGQPGPKGDRGPKGLPGPQG 235
            P GP G PG  GKPG PG                     LPG  G +GD G       +G
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445

Query: 236  LRGPKGDKGFGMPGAP 251
                +  +   +P  P
Sbjct: 1446 FVFTRHSQTTAIPSCP 1461


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  419 bits (1076), Expect = e-117
 Identities = 261/578 (45%), Positives = 302/578 (52%), Gaps = 92/578 (15%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175
            G++G  G PG  GPPG  G+ G  G PG  G PGP G PG  G+ G PG+PG  G  G P
Sbjct: 871  GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930

Query: 176  GAKGEIGQKGEIGPM------------------GIPGPQGPPGPHGLPGI-GKPGGPGLP 216
            GAKGE G KG  GP                   G PG +G  G  G+PG+ G  G PG  
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 217  GQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGV---- 271
            G PGP+GD G  G PG  GLRG  G  G  GMPG+ G +G  G  G  G  GLPG+    
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 272  --------------GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-G 316
                          G PG TG PG  G +GK G  G+PGP G +G  G +G PG PG  G
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 317  KPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGP---KGDRGMGGVPGALGP 373
             PG+ G  G  GF G KG  G PG+ GPPGLPG   PG PGP   +GD+G  G+PG  G 
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGF--PGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 374  RGEKGPIGAP----------GIGGPPGEPGLPGIPG---------PMGPPGAIGFPGPKG 414
            +GE G + AP          G  G  G PG PG+PG         P GP G  GFPGP G
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 415  EGGIV-----GPQGPPGPKGEPGLQGFPGKPG--FLGEVGPPGMRGLPGPIGPKGEAGQK 467
              G +     G +GPPG +G PG  G PG PG   +G  G  G  G PGP GP G AG  
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDM 1288

Query: 468  GVPG---LPGVPGLLGPKGEPGI---PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP 521
            G PG    PG PGL GP+G+PG    PG +G +G PG  G  GP GPIGP G PG +G+P
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348

Query: 522  G------LPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVM 574
            G      LPG PG PG  G+PG+ G  GPPG PG LGP G  G PG  G PG PG PA  
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPG-PAGE 1407

Query: 575  PPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPA 612
                  +GE  P    G+ G+K       K+G +G PA
Sbjct: 1408 KGNKGSKGEPGPAGSDGLPGLK------GKRGDSGSPA 1439



 Score =  406 bits (1044), Expect = e-113
 Identities = 267/635 (42%), Positives = 300/635 (47%), Gaps = 142/635 (22%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175
           +G  GP G PGP+GP G PGLPG  + G KG  G  G PG  G PG+PG PG  G  G+ 
Sbjct: 63  KGFTGPEGLPGPQGPKGFPGLPG--LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLV 120

Query: 176 GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKP-----------GGPGLPGQPG 220
           G  G  G KGE G  G+PG  G PG  G  G+    G P           G PGLPG PG
Sbjct: 121 GVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPG 180

Query: 221 PKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPG-----------------MHGPP 263
           P+G  GP G PGP G  GP G   FG PGA G +GP G                 + GPP
Sbjct: 181 PQGLPGPPGFPGPVGPPGPPGF--FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 238

Query: 264 GPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG-----VQGPPGIPGI-GK 317
           GP G   V   G       +G  G  GA GEPGP GP G+PG      +G PG PG+ GK
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGK 298

Query: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG----IGKPGFPGP---------KGDRGM 364
           PG+DG+PG PG  G KG +G PGL G  G+ G    IG PGF GP         KGD G 
Sbjct: 299 PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 365 GGVPGALGPRGEKGPIGAPGIGGPP----------------------------------- 389
            G PG  G RG +GP G PG+ G P                                   
Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 390 -----GEPGLPGIPGPMGPPGAIGF-PGPKGEGGIVGPQGPP------GPKGEPGL---- 433
                G PGLPG PGP GPPG I F  GP G+ G+ G  G P      GPKGEPGL    
Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 434 -------QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG------ 480
                   G PG PG  G  G PG +G  G  G  G  G  G+PG PG PG  G      
Sbjct: 479 CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 481 -------PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPK------GEPGLPGPP 527
                  P+G+ G+PGD GL+G PG  G+ G  G  G  G+PGPK      GE G  GPP
Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 528 GFPGI-GKPGVAGLHGPP-----GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQ 581
           G PG  G PG AG  GPP     G+PG  G QG PG PGPPG  GP G  +V  P P P 
Sbjct: 599 GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 582 GEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616
           G   P    G  G + P       GK G P    P
Sbjct: 659 G---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGP 690



 Score =  404 bits (1039), Expect = e-112
 Identities = 272/693 (39%), Positives = 307/693 (44%), Gaps = 203/693 (29%)

Query: 118  GEQGPRGE-------PGPRGPPGPPGLPGH----GIPGIKGK------PGPQGYPGVGKP 160
            GE GPRGE       PGP GPPGPPG PG     GIPG  GK      PGP G PG+   
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 161  GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPG 220
            G PG PG  G  G PG KG +G  G++G  G+PG  G PG  G P +  PGGPG PG PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 221  PKGDRGPKG------------LPGPQGLRGPKGDKGFGMPGAPGVKGPPG--MHGPPGPV 266
             +G+ G  G             PG +GL GP+GD G   PG PG +GPPG  + GP G  
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG--QPGPPGEQGPPGRCIEGPRGAQ 817

Query: 267  GLPGV---------------------------------GKPGVTGFPGPQGPLGKPGAPG 293
            GLPG+                                 G PG+ G  G  GPLG+ G PG
Sbjct: 818  GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG 877

Query: 294  EPGPQGP---------IGVPGVQGPPGIPGI-------GKPGQDGIPGQPGFPGGKGEQG 337
             PG  GP         +G PG  GPPG PG        G PG  G+ GQ G PG KGEQG
Sbjct: 878  NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQG 937

Query: 338  LPGLPGPP---------GLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAP---- 383
              G PGP          G PG+ G  G PG KG+RG+ G+PG  G +G  GP G P    
Sbjct: 938  DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRG 997

Query: 384  --GIGGPPGEPGLPGIPGPMG---------PPGAIGFPGPKGEGGIVGPQG--------- 423
              G  G PGEPGL GIPG MG           G +GFPG  G  G+ G  G         
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057

Query: 424  --------PPGPKGEPGL---------QGFPGKPGFLGEVGP------PGMRGLPGPIGP 460
                    PPGP G+PGL          G PG PG LG  GP      PG  GLPG  GP
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117

Query: 461  KGEAGQKGVPGLPGVPGLLGPKGEPGIPG---------DQGL------------------ 493
             G+ G KG+ GL G PG+ GP G PG PG         DQG                   
Sbjct: 1118 HGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA 1177

Query: 494  ----------------QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGV 537
                            +G PG PG+ G  G +G  G  GP G  G PGPPG PG   PG 
Sbjct: 1178 PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQ 1237

Query: 538  AGLHGPP---GKPGALGPQGQPGL--------PGPPGPPGPPGPPAVMPPTPPPQGEYLP 586
             G  GPP   G PGA GP G PG          G  G PGP GPP       PP     P
Sbjct: 1238 TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297

Query: 587  DMGLGIDGVKPP------HAYGAKKGKNGGPAY 613
                G  G+  P        +   KG+ G P +
Sbjct: 1298 ----GTPGLPGPRGDPGFQGFPGVKGEKGNPGF 1326



 Score =  399 bits (1025), Expect = e-111
 Identities = 263/640 (41%), Positives = 310/640 (48%), Gaps = 123/640 (19%)

Query: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157
            R G + +P       L   +GE    GE G +GPPG PG PG   PG  G  GP GY   
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS--PGPAGPAGPPGYGPQ 621

Query: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKGEI-------GPMGIPGPQGPPGPHGLPGI--- 207
            G+PG+ G  G PGA   PG  GE G +GE+       GP G PGP G PGP G PGI   
Sbjct: 622  GEPGLQGTQGVPGA---PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGS 678

Query: 208  -------------GKPGGPGL--PGQPGPKGDRG---------------PKGLPGPQGLR 237
                         G+PG PG+  PG PGPKGD+G                 GLPG  GL 
Sbjct: 679  LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLP 738

Query: 238  GPKGDKGFGMPGAPGVKGPPGMHGPPGP---VGLPGVGKPGVTGFPGPQGPLGKPGAPGE 294
            G KG+    MPG PG  G PG  G  G    +GLPG+  PG+ G PG +G  G  G PG+
Sbjct: 739  GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL--PGLPGTPGNEGLDGPRGDPGQ 796

Query: 295  PGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPG 354
            PGP      PG QGPPG    G  G  G+PG  G  G +G +G  G  G PG+PG+ + G
Sbjct: 797  PGP------PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 355  FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKG 414
            FPG  G  G+ G  G +GP G++G  G PGI GPPGE G+ G+   MG PGAIG PGP G
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGM---MGFPGAIGPPGPPG 907

Query: 415  EGGIVGPQGPP---------------------------------GPKGEPGLQGFPGKPG 441
              G  G +G P                                 G KGEPGL+GF G PG
Sbjct: 908  NPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967

Query: 442  FLGEVGPPGM------RGLPGPI---GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQG 492
              G  G PGM      +GLPGP    GP+G+ G  G PG PG+ G+ G  G  G+PG +G
Sbjct: 968  EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027

Query: 493  LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGL--------PGPPGFPGI----GKPGVAGL 540
             +G  G PG  G  G  G  G+ G KGEPG         PGP G PG+    GK G  G 
Sbjct: 1028 KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ 1087

Query: 541  HGPPGKPGALGPQGQPGLPGPPGPPGPPGP------PAVMPPTPPPQGEYLPDMGLGIDG 594
             GPPG  G  GP+G PG PG PG PG PGP        +     PP     P +  G  G
Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLP-GFPG 1146

Query: 595  VKPPHAYGAKKGKNG--GPAYEMPAFTAELTAPFPPVGAP 632
               P      +G++G  GPA E    T  L AP  P G P
Sbjct: 1147 SPGPMGIRGDQGRDGIPGPAGE-KGETGLLRAPPGPRGNP 1185



 Score =  393 bits (1009), Expect = e-109
 Identities = 269/662 (40%), Positives = 322/662 (48%), Gaps = 89/662 (13%)

Query: 35   PLPPQIP-PQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEI 93
            P PP  P PQ PP IP             L K G       P L      P +P      
Sbjct: 661  PGPPGHPGPQGPPGIPG-----------SLGKCG------DPGLPGPDGEPGIPGIGFPG 703

Query: 94   QPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQG 153
             P P+ G +  P     +      GE G  G+PG  G  G P +   G PG  G PG +G
Sbjct: 704  PPGPK-GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762

Query: 154  YPG----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP--QGPPGPHGLPGI 207
              G    +G PG+PG+PG PG  G+ G +G+ GQ G  G  G PG   +GP G  GLPG+
Sbjct: 763  NSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL 822

Query: 208  -------------GKPGGPGLPG--QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG 252
                         G  G PG+PG  + G  G+ G  G+PG QG  GP G +G+  PG PG
Sbjct: 823  NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY--PGNPG 880

Query: 253  VKGPPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311
            + GPPG  G  G +G PG +G PG  G PG  G  G PG PG  G +G  G  G QG  G
Sbjct: 881  ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 312  IPG-------IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRG 363
             PG       IG  G+ G+ G  G PG KG +G+PG+PG  GL G+ G  G PGP+GD G
Sbjct: 941  NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG 1000

Query: 364  MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG--- 420
              G PG  G RG  G +G  G+ G  G+ G  G PG  G PG  G  G +G+ G  G   
Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSE 1060

Query: 421  --PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGL 478
                GPPGP G+PGL G  GK G +G+ GPPG  G  GP G  G  G  G+PG PG  G 
Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD 1120

Query: 479  LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPI------GPPGIPGP---KGEPGL----PG 525
            LG KG  G+ G  G++GPPG+PG  G  GP+      G  GIPGP   KGE GL    PG
Sbjct: 1121 LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180

Query: 526  PPGFPGI-------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTP 578
            P G PG        G PG  GL G  G  G  GP+G  G+ G PGPPG PG  A++P   
Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG--AIIPGQT 1238

Query: 579  PPQGEYLPDMGLGIDGVKPP------HAYGAK--KGKNGGPAYEMPAFTAELTAPFPPVG 630
              +G   P    G  G   P      H  G K  KG  G P  + P  TA    P   +G
Sbjct: 1239 GNRG---PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 631  AP 632
            AP
Sbjct: 1296 AP 1297



 Score =  374 bits (959), Expect = e-103
 Identities = 226/494 (45%), Positives = 255/494 (51%), Gaps = 80/494 (16%)

Query: 113  LASLRGEQGPRGEPGPRGP------PGPPGLPG-------HGIPGIKGKPGPQGYPG-VG 158
            L  L+G  GP G PGPRG       PG PGL G        G+PG KGK G  G+PG  G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 159  KPGMPGM-----------------PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGP 201
            +PG+PG+                 PG PG  G PG  G++G+KGE+G  G PG  GP GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 202  HGLPGIGKPGGPGLPGQPGPKGD---RGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPP 257
             G PG   PG PGLPG+PGP GD   +G KGL GP G+RGP G  GF G PG  G++G  
Sbjct: 1100 EGAPG--SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQ 1157

Query: 258  GMHGPPGPVGLPGV-----GKPGVTGFPGPQGPLGKPGAPGEPG------------PQGP 300
            G  G PGP G  G        PG  G PG QG  G  GAPG PG            P+GP
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217

Query: 301  IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360
             G+ G  GPPG+PG   PGQ G  G PG       +G PG PGPPG PG    G    KG
Sbjct: 1218 TGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSHVIGI---KG 1268

Query: 361  DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420
            D+G  G PG  GP G  G +G PG  G PG PGL   PGP G PG  GFPG KGE     
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL---PGPRGDPGFQGFPGVKGE----- 1320

Query: 421  PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
                   KG PG  G  G PG +G  GPPG+RG PG +      G  G PG PG PG+ G
Sbjct: 1321 -------KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 481  PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540
              G PG PG+ G  GP G PG  G  G  GP G  G KG  G PGP G  G+  PG+ G 
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL--PGLKGK 1431

Query: 541  HGPPGKPGALGPQG 554
             G  G P     +G
Sbjct: 1432 RGDSGSPATWTTRG 1445



 Score =  268 bits (684), Expect = 2e-71
 Identities = 168/397 (42%), Positives = 194/397 (48%), Gaps = 60/397 (15%)

Query: 87   PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIK 146
            P Y +  +P P  G    P    ++      G+ GP G  GP GP G PG PG   PG+ 
Sbjct: 1056 PGYSEGTRPGPP-GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS--PGLP 1112

Query: 147  GKPGPQG---YPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG----- 197
            GKPGP G   + G+ G  G PG+ G PG  G PG+ G +G +G+ G  GIPGP G     
Sbjct: 1113 GKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172

Query: 198  -----PPGPHGLPGI-------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF 245
                 PPGP G PG        G PG PGLPG+ G  GD GP+G  G +G  GP G  G 
Sbjct: 1173 GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232

Query: 246  GMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305
             +PG  G +GPPG  G PG  G PG     V G  G +G +G PG  G PG  G +G PG
Sbjct: 1233 IIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 306  VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPG---------PPGLPGI------ 350
              G PG PG+  PG  G PG  GFPG KGE+G PG  G         P G PG+      
Sbjct: 1293 RLGAPGTPGL--PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 351  -------GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA---PGIGGPPGEPGLPGIPGP 400
                   G PG PG  G+ GM G PG  GP G  GP G    PG  G PG P        
Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTP-------- 1402

Query: 401  MGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP 437
             GP G  G  G KGE G  G  G PG KG+ G  G P
Sbjct: 1403 -GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score =  196 bits (497), Expect = 9e-50
 Identities = 132/313 (42%), Positives = 149/313 (47%), Gaps = 50/313 (15%)

Query: 325 GQPGFPGGKGEQGLPGLPGPPGLPG----IGKPGFPGPKGDRGMGGVPGALGPRGEKGPI 380
           GQ    G KGE+G  G PGPPG PG     G  G PGP+G +G  G+PG  G +G +G  
Sbjct: 37  GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 381 GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP 440
           G PG  G    PGLPG PG  GP G +G PG  G             KGE   QGFPG P
Sbjct: 97  GLPGFSG---SPGLPGTPGNTGPYGLVGVPGCSGS------------KGE---QGFPGLP 138

Query: 441 GFLGEVGPPGMRGLPGPIGPKG-----EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQG 495
           G LG  G PG  GL G  G        E   KG PGLPG PG  G  G PG PG  G  G
Sbjct: 139 GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG 198

Query: 496 PPGIPGIGGPSGPIGPPG-----IPGPKGE---PGLPGPPGFPGIGKPGVAGLHGPPGKP 547
           PPG  G  G  GP GP G     + G KGE    GL GPPG PG     +  L GP  + 
Sbjct: 199 PPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG---TVIVTLTGPDNRT 255

Query: 548 GALGPQGQPGLPGPPGPPGPPGPPAV-------MPPTPPPQGEYLPDMGL----GIDGVK 596
              G +G  G  G PGPPGP G P          P  P  QG+   D G+    G +GVK
Sbjct: 256 DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKD-GVPGFPGSEGVK 314

Query: 597 PPHAYGAKKGKNG 609
               +    G++G
Sbjct: 315 GNRGFPGLMGEDG 327



 Score =  187 bits (475), Expect = 3e-47
 Identities = 115/267 (43%), Positives = 134/267 (50%), Gaps = 18/267 (6%)

Query: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420
           D+G     GA G +GEKG  G PG  G  G  G  G+PGP GP G  G PG  G  G+ G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
             G PG  G PGL G PG  G  G VG PG  G  G  G  G  G  G PG+PG  GL G
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 481 PKGEPGIPGDQGL--QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVA 538
            KG P    D  L  +G PG+PG  GP G  GPPG PGP G    PGPPGF   G PG  
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGF--FGFPGAM 209

Query: 539 GLHGPPGKPG--ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMG----LGI 592
           G  GP G  G   +G +G+ G+ G  GPPGPPG   V    P  + +   + G    +G 
Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 593 DGVK-----PPHAYGAKKGKNGGPAYE 614
            G       P  +YG++KG  G P  +
Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQ 296



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 69/196 (35%), Positives = 85/196 (43%), Gaps = 60/196 (30%)

Query: 116  LRGEQGPRGEPGPRGPPG------PPGLPGH----GIPGIKGKPGPQGYPGV-------- 157
            ++G++G  G PGP+GPPG      PPG  G     G+PG +G PG QG+PGV        
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 158  --------------GKPGMPGMPGK------PGAMGMPGAKGEIGQKGEIGPMGIPGPQG 197
                          G PG+ G PG       PG+ G PG  GE G +GE GP G PG  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 198  PPGPHGLPGI-GKPGGPG---------------------LPGQPGPKGDRGPKGLPGPQG 235
            P GP G PG  GKPG PG                     LPG  G +GD G       +G
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445

Query: 236  LRGPKGDKGFGMPGAP 251
                +  +   +P  P
Sbjct: 1446 FVFTRHSQTTAIPSCP 1461


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  419 bits (1076), Expect = e-117
 Identities = 261/578 (45%), Positives = 302/578 (52%), Gaps = 92/578 (15%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175
            G++G  G PG  GPPG  G+ G  G PG  G PGP G PG  G+ G PG+PG  G  G P
Sbjct: 871  GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930

Query: 176  GAKGEIGQKGEIGPM------------------GIPGPQGPPGPHGLPGI-GKPGGPGLP 216
            GAKGE G KG  GP                   G PG +G  G  G+PG+ G  G PG  
Sbjct: 931  GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990

Query: 217  GQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGV---- 271
            G PGP+GD G  G PG  GLRG  G  G  GMPG+ G +G  G  G  G  GLPG+    
Sbjct: 991  GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 272  --------------GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-G 316
                          G PG TG PG  G +GK G  G+PGP G +G  G +G PG PG  G
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 317  KPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGP---KGDRGMGGVPGALGP 373
             PG+ G  G  GF G KG  G PG+ GPPGLPG   PG PGP   +GD+G  G+PG  G 
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGF--PGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 374  RGEKGPIGAP----------GIGGPPGEPGLPGIPG---------PMGPPGAIGFPGPKG 414
            +GE G + AP          G  G  G PG PG+PG         P GP G  GFPGP G
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 415  EGGIV-----GPQGPPGPKGEPGLQGFPGKPG--FLGEVGPPGMRGLPGPIGPKGEAGQK 467
              G +     G +GPPG +G PG  G PG PG   +G  G  G  G PGP GP G AG  
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDM 1288

Query: 468  GVPG---LPGVPGLLGPKGEPGI---PGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP 521
            G PG    PG PGL GP+G+PG    PG +G +G PG  G  GP GPIGP G PG +G+P
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348

Query: 522  G------LPGPPGFPGI-GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVM 574
            G      LPG PG PG  G+PG+ G  GPPG PG LGP G  G PG  G PG PG PA  
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPG-PAGE 1407

Query: 575  PPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPA 612
                  +GE  P    G+ G+K       K+G +G PA
Sbjct: 1408 KGNKGSKGEPGPAGSDGLPGLK------GKRGDSGSPA 1439



 Score =  406 bits (1044), Expect = e-113
 Identities = 267/635 (42%), Positives = 300/635 (47%), Gaps = 142/635 (22%)

Query: 117 RGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175
           +G  GP G PGP+GP G PGLPG  + G KG  G  G PG  G PG+PG PG  G  G+ 
Sbjct: 63  KGFTGPEGLPGPQGPKGFPGLPG--LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLV 120

Query: 176 GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKP-----------GGPGLPGQPG 220
           G  G  G KGE G  G+PG  G PG  G  G+    G P           G PGLPG PG
Sbjct: 121 GVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPG 180

Query: 221 PKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPG-----------------MHGPP 263
           P+G  GP G PGP G  GP G   FG PGA G +GP G                 + GPP
Sbjct: 181 PQGLPGPPGFPGPVGPPGPPGF--FGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 238

Query: 264 GPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG-----VQGPPGIPGI-GK 317
           GP G   V   G       +G  G  GA GEPGP GP G+PG      +G PG PG+ GK
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGK 298

Query: 318 PGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPG----IGKPGFPGP---------KGDRGM 364
           PG+DG+PG PG  G KG +G PGL G  G+ G    IG PGF GP         KGD G 
Sbjct: 299 PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 365 GGVPGALGPRGEKGPIGAPGIGGPP----------------------------------- 389
            G PG  G RG +GP G PG+ G P                                   
Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 390 -----GEPGLPGIPGPMGPPGAIGF-PGPKGEGGIVGPQGPP------GPKGEPGL---- 433
                G PGLPG PGP GPPG I F  GP G+ G+ G  G P      GPKGEPGL    
Sbjct: 419 SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 434 -------QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG------ 480
                   G PG PG  G  G PG +G  G  G  G  G  G+PG PG PG  G      
Sbjct: 479 CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 481 -------PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPK------GEPGLPGPP 527
                  P+G+ G+PGD GL+G PG  G+ G  G  G  G+PGPK      GE G  GPP
Sbjct: 539 EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 528 GFPGI-GKPGVAGLHGPP-----GKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQ 581
           G PG  G PG AG  GPP     G+PG  G QG PG PGPPG  GP G  +V  P P P 
Sbjct: 599 GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 582 GEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616
           G   P    G  G + P       GK G P    P
Sbjct: 659 G---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGP 690



 Score =  404 bits (1039), Expect = e-112
 Identities = 272/693 (39%), Positives = 307/693 (44%), Gaps = 203/693 (29%)

Query: 118  GEQGPRGE-------PGPRGPPGPPGLPGH----GIPGIKGK------PGPQGYPGVGKP 160
            GE GPRGE       PGP GPPGPPG PG     GIPG  GK      PGP G PG+   
Sbjct: 640  GEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI 699

Query: 161  GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPG 220
            G PG PG  G  G PG KG +G  G++G  G+PG  G PG  G P +  PGGPG PG PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 221  PKGDRGPKG------------LPGPQGLRGPKGDKGFGMPGAPGVKGPPG--MHGPPGPV 266
             +G+ G  G             PG +GL GP+GD G   PG PG +GPPG  + GP G  
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG--QPGPPGEQGPPGRCIEGPRGAQ 817

Query: 267  GLPGV---------------------------------GKPGVTGFPGPQGPLGKPGAPG 293
            GLPG+                                 G PG+ G  G  GPLG+ G PG
Sbjct: 818  GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG 877

Query: 294  EPGPQGP---------IGVPGVQGPPGIPGI-------GKPGQDGIPGQPGFPGGKGEQG 337
             PG  GP         +G PG  GPPG PG        G PG  G+ GQ G PG KGEQG
Sbjct: 878  NPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQG 937

Query: 338  LPGLPGPP---------GLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAP---- 383
              G PGP          G PG+ G  G PG KG+RG+ G+PG  G +G  GP G P    
Sbjct: 938  DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRG 997

Query: 384  --GIGGPPGEPGLPGIPGPMG---------PPGAIGFPGPKGEGGIVGPQG--------- 423
              G  G PGEPGL GIPG MG           G +GFPG  G  G+ G  G         
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057

Query: 424  --------PPGPKGEPGL---------QGFPGKPGFLGEVGP------PGMRGLPGPIGP 460
                    PPGP G+PGL          G PG PG LG  GP      PG  GLPG  GP
Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117

Query: 461  KGEAGQKGVPGLPGVPGLLGPKGEPGIPG---------DQGL------------------ 493
             G+ G KG+ GL G PG+ GP G PG PG         DQG                   
Sbjct: 1118 HGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA 1177

Query: 494  ----------------QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGV 537
                            +G PG PG+ G  G +G  G  GP G  G PGPPG PG   PG 
Sbjct: 1178 PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQ 1237

Query: 538  AGLHGPP---GKPGALGPQGQPGL--------PGPPGPPGPPGPPAVMPPTPPPQGEYLP 586
             G  GPP   G PGA GP G PG          G  G PGP GPP       PP     P
Sbjct: 1238 TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297

Query: 587  DMGLGIDGVKPP------HAYGAKKGKNGGPAY 613
                G  G+  P        +   KG+ G P +
Sbjct: 1298 ----GTPGLPGPRGDPGFQGFPGVKGEKGNPGF 1326



 Score =  399 bits (1025), Expect = e-111
 Identities = 263/640 (41%), Positives = 310/640 (48%), Gaps = 123/640 (19%)

Query: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV 157
            R G + +P       L   +GE    GE G +GPPG PG PG   PG  G  GP GY   
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS--PGPAGPAGPPGYGPQ 621

Query: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKGEI-------GPMGIPGPQGPPGPHGLPGI--- 207
            G+PG+ G  G PGA   PG  GE G +GE+       GP G PGP G PGP G PGI   
Sbjct: 622  GEPGLQGTQGVPGA---PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGS 678

Query: 208  -------------GKPGGPGL--PGQPGPKGDRG---------------PKGLPGPQGLR 237
                         G+PG PG+  PG PGPKGD+G                 GLPG  GL 
Sbjct: 679  LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLP 738

Query: 238  GPKGDKGFGMPGAPGVKGPPGMHGPPGP---VGLPGVGKPGVTGFPGPQGPLGKPGAPGE 294
            G KG+    MPG PG  G PG  G  G    +GLPG+  PG+ G PG +G  G  G PG+
Sbjct: 739  GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL--PGLPGTPGNEGLDGPRGDPGQ 796

Query: 295  PGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPG 354
            PGP      PG QGPPG    G  G  G+PG  G  G +G +G  G  G PG+PG+ + G
Sbjct: 797  PGP------PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 355  FPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKG 414
            FPG  G  G+ G  G +GP G++G  G PGI GPPGE G+ G+   MG PGAIG PGP G
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGM---MGFPGAIGPPGPPG 907

Query: 415  EGGIVGPQGPP---------------------------------GPKGEPGLQGFPGKPG 441
              G  G +G P                                 G KGEPGL+GF G PG
Sbjct: 908  NPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967

Query: 442  FLGEVGPPGM------RGLPGPI---GPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQG 492
              G  G PGM      +GLPGP    GP+G+ G  G PG PG+ G+ G  G  G+PG +G
Sbjct: 968  EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027

Query: 493  LQGPPGIPGIGGPSGPIGPPGIPGPKGEPGL--------PGPPGFPGI----GKPGVAGL 540
             +G  G PG  G  G  G  G+ G KGEPG         PGP G PG+    GK G  G 
Sbjct: 1028 KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ 1087

Query: 541  HGPPGKPGALGPQGQPGLPGPPGPPGPPGP------PAVMPPTPPPQGEYLPDMGLGIDG 594
             GPPG  G  GP+G PG PG PG PG PGP        +     PP     P +  G  G
Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLP-GFPG 1146

Query: 595  VKPPHAYGAKKGKNG--GPAYEMPAFTAELTAPFPPVGAP 632
               P      +G++G  GPA E    T  L AP  P G P
Sbjct: 1147 SPGPMGIRGDQGRDGIPGPAGE-KGETGLLRAPPGPRGNP 1185



 Score =  393 bits (1009), Expect = e-109
 Identities = 269/662 (40%), Positives = 322/662 (48%), Gaps = 89/662 (13%)

Query: 35   PLPPQIP-PQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEI 93
            P PP  P PQ PP IP             L K G       P L      P +P      
Sbjct: 661  PGPPGHPGPQGPPGIPG-----------SLGKCG------DPGLPGPDGEPGIPGIGFPG 703

Query: 94   QPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQG 153
             P P+ G +  P     +      GE G  G+PG  G  G P +   G PG  G PG +G
Sbjct: 704  PPGPK-GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762

Query: 154  YPG----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP--QGPPGPHGLPGI 207
              G    +G PG+PG+PG PG  G+ G +G+ GQ G  G  G PG   +GP G  GLPG+
Sbjct: 763  NSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL 822

Query: 208  -------------GKPGGPGLPG--QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG 252
                         G  G PG+PG  + G  G+ G  G+PG QG  GP G +G+  PG PG
Sbjct: 823  NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY--PGNPG 880

Query: 253  VKGPPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPG 311
            + GPPG  G  G +G PG +G PG  G PG  G  G PG PG  G +G  G  G QG  G
Sbjct: 881  ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKG 940

Query: 312  IPG-------IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRG 363
             PG       IG  G+ G+ G  G PG KG +G+PG+PG  GL G+ G  G PGP+GD G
Sbjct: 941  NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG 1000

Query: 364  MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG--- 420
              G PG  G RG  G +G  G+ G  G+ G  G PG  G PG  G  G +G+ G  G   
Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSE 1060

Query: 421  --PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGL 478
                GPPGP G+PGL G  GK G +G+ GPPG  G  GP G  G  G  G+PG PG  G 
Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD 1120

Query: 479  LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPI------GPPGIPGP---KGEPGL----PG 525
            LG KG  G+ G  G++GPPG+PG  G  GP+      G  GIPGP   KGE GL    PG
Sbjct: 1121 LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180

Query: 526  PPGFPGI-------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTP 578
            P G PG        G PG  GL G  G  G  GP+G  G+ G PGPPG PG  A++P   
Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG--AIIPGQT 1238

Query: 579  PPQGEYLPDMGLGIDGVKPP------HAYGAK--KGKNGGPAYEMPAFTAELTAPFPPVG 630
              +G   P    G  G   P      H  G K  KG  G P  + P  TA    P   +G
Sbjct: 1239 GNRG---PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 631  AP 632
            AP
Sbjct: 1296 AP 1297



 Score =  374 bits (959), Expect = e-103
 Identities = 226/494 (45%), Positives = 255/494 (51%), Gaps = 80/494 (16%)

Query: 113  LASLRGEQGPRGEPGPRGP------PGPPGLPG-------HGIPGIKGKPGPQGYPG-VG 158
            L  L+G  GP G PGPRG       PG PGL G        G+PG KGK G  G+PG  G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAG 1039

Query: 159  KPGMPGM-----------------PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGP 201
            +PG+PG+                 PG PG  G PG  G++G+KGE+G  G PG  GP GP
Sbjct: 1040 RPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP 1099

Query: 202  HGLPGIGKPGGPGLPGQPGPKGD---RGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPP 257
             G PG   PG PGLPG+PGP GD   +G KGL GP G+RGP G  GF G PG  G++G  
Sbjct: 1100 EGAPG--SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQ 1157

Query: 258  GMHGPPGPVGLPGV-----GKPGVTGFPGPQGPLGKPGAPGEPG------------PQGP 300
            G  G PGP G  G        PG  G PG QG  G  GAPG PG            P+GP
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217

Query: 301  IGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360
             G+ G  GPPG+PG   PGQ G  G PG       +G PG PGPPG PG    G    KG
Sbjct: 1218 TGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSHVIGI---KG 1268

Query: 361  DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420
            D+G  G PG  GP G  G +G PG  G PG PGL   PGP G PG  GFPG KGE     
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL---PGPRGDPGFQGFPGVKGE----- 1320

Query: 421  PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
                   KG PG  G  G PG +G  GPPG+RG PG +      G  G PG PG PG+ G
Sbjct: 1321 -------KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 481  PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540
              G PG PG+ G  GP G PG  G  G  GP G  G KG  G PGP G  G+  PG+ G 
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL--PGLKGK 1431

Query: 541  HGPPGKPGALGPQG 554
             G  G P     +G
Sbjct: 1432 RGDSGSPATWTTRG 1445



 Score =  268 bits (684), Expect = 2e-71
 Identities = 168/397 (42%), Positives = 194/397 (48%), Gaps = 60/397 (15%)

Query: 87   PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIK 146
            P Y +  +P P  G    P    ++      G+ GP G  GP GP G PG PG   PG+ 
Sbjct: 1056 PGYSEGTRPGPP-GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS--PGLP 1112

Query: 147  GKPGPQG---YPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG----- 197
            GKPGP G   + G+ G  G PG+ G PG  G PG+ G +G +G+ G  GIPGP G     
Sbjct: 1113 GKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172

Query: 198  -----PPGPHGLPGI-------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF 245
                 PPGP G PG        G PG PGLPG+ G  GD GP+G  G +G  GP G  G 
Sbjct: 1173 GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232

Query: 246  GMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305
             +PG  G +GPPG  G PG  G PG     V G  G +G +G PG  G PG  G +G PG
Sbjct: 1233 IIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPG 1292

Query: 306  VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPG---------PPGLPGI------ 350
              G PG PG+  PG  G PG  GFPG KGE+G PG  G         P G PG+      
Sbjct: 1293 RLGAPGTPGL--PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 351  -------GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA---PGIGGPPGEPGLPGIPGP 400
                   G PG PG  G+ GM G PG  GP G  GP G    PG  G PG P        
Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTP-------- 1402

Query: 401  MGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFP 437
             GP G  G  G KGE G  G  G PG KG+ G  G P
Sbjct: 1403 -GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score =  196 bits (497), Expect = 9e-50
 Identities = 132/313 (42%), Positives = 149/313 (47%), Gaps = 50/313 (15%)

Query: 325 GQPGFPGGKGEQGLPGLPGPPGLPG----IGKPGFPGPKGDRGMGGVPGALGPRGEKGPI 380
           GQ    G KGE+G  G PGPPG PG     G  G PGP+G +G  G+PG  G +G +G  
Sbjct: 37  GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 381 GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP 440
           G PG  G    PGLPG PG  GP G +G PG  G             KGE   QGFPG P
Sbjct: 97  GLPGFSG---SPGLPGTPGNTGPYGLVGVPGCSGS------------KGE---QGFPGLP 138

Query: 441 GFLGEVGPPGMRGLPGPIGPKG-----EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQG 495
           G LG  G PG  GL G  G        E   KG PGLPG PG  G  G PG PG  G  G
Sbjct: 139 GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG 198

Query: 496 PPGIPGIGGPSGPIGPPG-----IPGPKGE---PGLPGPPGFPGIGKPGVAGLHGPPGKP 547
           PPG  G  G  GP GP G     + G KGE    GL GPPG PG     +  L GP  + 
Sbjct: 199 PPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG---TVIVTLTGPDNRT 255

Query: 548 GALGPQGQPGLPGPPGPPGPPGPPAV-------MPPTPPPQGEYLPDMGL----GIDGVK 596
              G +G  G  G PGPPGP G P          P  P  QG+   D G+    G +GVK
Sbjct: 256 DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKD-GVPGFPGSEGVK 314

Query: 597 PPHAYGAKKGKNG 609
               +    G++G
Sbjct: 315 GNRGFPGLMGEDG 327



 Score =  187 bits (475), Expect = 3e-47
 Identities = 115/267 (43%), Positives = 134/267 (50%), Gaps = 18/267 (6%)

Query: 361 DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVG 420
           D+G     GA G +GEKG  G PG  G  G  G  G+PGP GP G  G PG  G  G+ G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480
             G PG  G PGL G PG  G  G VG PG  G  G  G  G  G  G PG+PG  GL G
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 481 PKGEPGIPGDQGL--QGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVA 538
            KG P    D  L  +G PG+PG  GP G  GPPG PGP G    PGPPGF   G PG  
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGF--FGFPGAM 209

Query: 539 GLHGPPGKPG--ALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMG----LGI 592
           G  GP G  G   +G +G+ G+ G  GPPGPPG   V    P  + +   + G    +G 
Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 593 DGVK-----PPHAYGAKKGKNGGPAYE 614
            G       P  +YG++KG  G P  +
Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQ 296



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 69/196 (35%), Positives = 85/196 (43%), Gaps = 60/196 (30%)

Query: 116  LRGEQGPRGEPGPRGPPG------PPGLPGH----GIPGIKGKPGPQGYPGV-------- 157
            ++G++G  G PGP+GPPG      PPG  G     G+PG +G PG QG+PGV        
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG 1325

Query: 158  --------------GKPGMPGMPGK------PGAMGMPGAKGEIGQKGEIGPMGIPGPQG 197
                          G PG+ G PG       PG+ G PG  GE G +GE GP G PG  G
Sbjct: 1326 FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG 1385

Query: 198  PPGPHGLPGI-GKPGGPG---------------------LPGQPGPKGDRGPKGLPGPQG 235
            P GP G PG  GKPG PG                     LPG  G +GD G       +G
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445

Query: 236  LRGPKGDKGFGMPGAP 251
                +  +   +P  P
Sbjct: 1446 FVFTRHSQTTAIPSCP 1461


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  418 bits (1074), Expect = e-116
 Identities = 283/699 (40%), Positives = 320/699 (45%), Gaps = 124/699 (17%)

Query: 55   GQQVPHMPLAKDGLAMGKEMPHLQYGKE---YPHLPQYMKEIQPAPRMGKEAVPKKGKEI 111
            G+  P  P  + G       P L   K     P LP Y     P   +G    P    E 
Sbjct: 680  GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 739

Query: 112  PLASLRGEQGPRGEPGPRGPPGPPGLPG----------------HGIPGIKGKPGPQGYP 155
                L G+ GPRGE GP GP G  G  G                HG PG +G PGPQG  
Sbjct: 740  GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 799

Query: 156  GV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGP 213
            G  G  G PG PGK G  G PG +GE+G +G+ GP G PG  GP G  G  G +G+ G P
Sbjct: 800  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 859

Query: 214  GLPGQPGP------------KGDRGPKGLPG---PQGLRGPKGDKGF-GMPGAPGVKGPP 257
            G PG PG             KGD GP G PG   P GLRG  G++G  G  G PG+KG  
Sbjct: 860  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 919

Query: 258  GMHGPPGPVGLPG----------VGKPGVTGFPGPQGPLGKPGAPGEPGP---------Q 298
            G  GPPGP G PG          +G PG  G  GP G  G+ G PGE GP         Q
Sbjct: 920  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979

Query: 299  GPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGP------PGLPGI- 350
            GP+G+PG  GPPG+ G  G  G+ G PGQ G  G KGE G PG PGP      PG  G  
Sbjct: 980  GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1039

Query: 351  GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410
            G+PG  GP+G  G  G  G  G  G  GPIG  G+ GP GE G  G  GPMGPPG  G  
Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099

Query: 411  GPKGEGGIVGPQGPPG---------PKGEPGLQGFPG------------------KPGFL 443
            GP G  G  GPQGPPG          KGEPG  G PG                  + G  
Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1159

Query: 444  GEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIG 503
            GE GPPG +G  G  GPKG  G  G PG PG PG  GP+G+ G  GD+G  G PG PG  
Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1219

Query: 504  GPSGPIGPPGI------------------PGPKGEPGLPGPPGFPG-------IGKPGVA 538
            GP+G  GPPG                    G KG+PG  G PG  G        GKPG  
Sbjct: 1220 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1279

Query: 539  GLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPP 598
            GL G PG  G  G  G  G  GPPGP GPPG P +         +  P + +G+ G  PP
Sbjct: 1280 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL-IGLIG--PP 1336

Query: 599  HAYGAK-----KGKNGGPAYEMPAFTAELTAPFPPVGAP 632
               G K      G  G P  +        + P  P G P
Sbjct: 1337 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1375



 Score =  416 bits (1070), Expect = e-116
 Identities = 265/643 (41%), Positives = 296/643 (46%), Gaps = 146/643 (22%)

Query: 116  LRGEQGPRGEPGPRGPPGPPG---LPGH----GIPGIKGKPGPQGYPGV----------- 157
            L G QGP G PGP+GPPGPPG   LPGH    G  G +GK GP G PGV           
Sbjct: 792  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 851

Query: 158  --GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKPG 211
              G+ G PG PG PG  G+PG  G+ G KG+ GP G PG  GP G  G PG     G  G
Sbjct: 852  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 911

Query: 212  GPGLPGQPGPKGDRGPKGLPG------------PQGLRGPKGDKGF----GMPGAPGVKG 255
            GPGL G  GP G  GP G PG            P G  GP+G  G     G+PG  G  G
Sbjct: 912  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 971

Query: 256  PPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGA------------PGEPGPQGPIG 302
            P G  G  GPVGLPG  G PGV G  G +G +G PG             PG PGP GP+G
Sbjct: 972  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031

Query: 303  VPGVQGPPGIPGI-------------------GKPGQDGIPGQPGFPGGKGEQGLPGLPG 343
             PG  G  G PG                    G PG  G+ G PG  G KGE G  G  G
Sbjct: 1032 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1091

Query: 344  PPGLPG-------------------IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPG 384
            PPG PG                   +G  G PG KG+ G  G PG  G  G KGP G  G
Sbjct: 1092 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1151

Query: 385  IGGPPGEPGLPGIPGPMGP---------PGAIGFPG---PKGEGGIVGPQGPPGPKGEPG 432
              G  G+PG PG PGP GP         PG +GFPG   P GEGG  G  G  G +GE G
Sbjct: 1152 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG 1211

Query: 433  LQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG------------ 480
              G PG PG  GE GPPG  G  GP G  G  G++G  G  G PG +G            
Sbjct: 1212 EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1271

Query: 481  PKGEPG------IPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-- 532
            P G+PG      +PG  G QG PG  G  GP GP+GPPG+PG +G+ G  G  G PG+  
Sbjct: 1272 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1331

Query: 533  --------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEY 584
                    G+ G  GL GP G PG  G  G PG  GP GP GPPG P    P        
Sbjct: 1332 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK------- 1384

Query: 585  LPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFP 627
                  G  G   P     +KG  G P +  P    E+  P P
Sbjct: 1385 ------GAKGATGPGGPKGEKGVQGPPGH--PGPPGEVIQPLP 1419



 Score =  409 bits (1050), Expect = e-114
 Identities = 292/751 (38%), Positives = 339/751 (45%), Gaps = 184/751 (24%)

Query: 41  PPQMPPQI--PQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMK--EIQPA 96
           P Q P ++  PQ Q    Q P  P  ++ +     +P L+   E  H P+ +K  + +PA
Sbjct: 248 PQQQPSRLHRPQNQEPQSQDP-TPGEEEEILESSLLPPLE---EAAHGPRGLKGEKGEPA 303

Query: 97  ---PRMGKEAVPKKGKEIPLA-----SLRGEQGPRGEPGPRGPPGPPGLPGH-GIPG--- 144
              P M  E  P  G E P        ++G  GP G+PG RGPPG  GLPG  G PG   
Sbjct: 304 VLEPGMLVEGPP--GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPG 361

Query: 145 -------------------------------------IKGKPGPQGYPG----VGKPGMP 163
                                                ++G PGP GY G    +G+PG P
Sbjct: 362 TSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSP 421

Query: 164 GMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-------GKPGGPGLP 216
           G+ G+ G +G  G +G  G  G  G  G  G  G  G  G+PG        G  G PGLP
Sbjct: 422 GLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLP 481

Query: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGVGKPG 275
           G+ G +GD G +GLPGP G  G +GD G  G  G PG  GP G+ GP GP G+PG   PG
Sbjct: 482 GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG--PPG 539

Query: 276 VTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI----------GKPGQDGIPG 325
           V G  GPQGP G  G  GEPGP G  G PG QG PG  G           GKPG  G+PG
Sbjct: 540 VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599

Query: 326 QPGFPGGKGEQGLPGL---------------PGPPGLPGI-------------GKPGFPG 357
             G PG  G++G PG                PGP G+ G+             G+ GFPG
Sbjct: 600 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 659

Query: 358 ------PKGDRGMGGVPGAL------GPRGEKGPIGAPGIGGPPGE------PGLPGIPG 399
                  KGDRG  GVPG+       GP+G  GP G PG  G  GE      PGLPG PG
Sbjct: 660 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 719

Query: 400 PMGPPGAIGFP------------------GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPG 441
             GP G++GFP                  GP+GE G  GP+G  GP+G  G  G  G  G
Sbjct: 720 RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 779

Query: 442 FLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG 501
             G  GPPG RGLPGP GP G  G KG PG PG  GL G  G+ G  G QG  GPPG PG
Sbjct: 780 GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 839

Query: 502 IGGPSGPIGP---------PGIPGPKGEPGL------------PGPPGFPGIGKPGVAGL 540
           + GP G  G          PG PGP GE GL            PGPPG P  GK G AGL
Sbjct: 840 VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP--GKDGPAGL 897

Query: 541 HGPPGKPGALGPQGQPGLPGPPGPPGPPGP--------------PAVMPPTPPPQGEYLP 586
            G PG+ G  G  G PGL G  GP GPPGP              P   P  P PQG    
Sbjct: 898 RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 957

Query: 587 DMGLGIDGVKPPHAYGAKKGKNGGPAYEMPA 617
               G+ G K P     + G  G      PA
Sbjct: 958 AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA 988



 Score =  383 bits (983), Expect = e-106
 Identities = 257/636 (40%), Positives = 301/636 (47%), Gaps = 120/636 (18%)

Query: 85  HLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPG--PPGLPGHGI 142
           H PQ  +     P  G+E    +   +P        GPRG  G +G P    PG+     
Sbjct: 256 HRPQNQEPQSQDPTPGEEEEILESSLLPPLE-EAAHGPRGLKGEKGEPAVLEPGML---- 310

Query: 143 PGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP------- 195
             ++G PGP+G  G+  P  PG+ G PG +G PG +G  G+ G  G  G PGP       
Sbjct: 311 --VEGPPGPEGPAGLIGP--PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 366

Query: 196 ---------------------------------QGPPGPHGLPG----IGKPGGPGLPGQ 218
                                            +GPPGP G  G    +G+PG PGL G+
Sbjct: 367 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 426

Query: 219 P---GPKGDRGPKGLPGPQGLRGPKG----DKGFGMPGAPGVKGPPGMHGPPGPVGLPG- 270
               GP+G RGP+GL GP G  G +G    D   GMPG PGVKG  G  G P   GLPG 
Sbjct: 427 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP---GLPGE 483

Query: 271 VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFP 330
            G  G TG  G  GP G+ G  G+ G  GP G+PG  GP G+  +G  G  GIPG PG  
Sbjct: 484 KGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL--LGPKGPPGIPGPPGVR 541

Query: 331 GGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPG 390
           G  G QG  G  GP G P  G PG  G  G +G+ G  GA+GP GEKGP G PG+ G PG
Sbjct: 542 GMDGPQGPKGSLGPQGEP--GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599

Query: 391 EPGLPGIP------------GPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPG 438
             G PG P            GP GP G +G+PGP+G  G+ G +G  G KGE G  GFPG
Sbjct: 600 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 659

Query: 439 KPGFL------GEVGPPGMRGLPGPIGPK---------------GEAGQKGVPGLPGVPG 477
             G +      GEVG PG RG  GP GPK               GE G+ GVPGLPG PG
Sbjct: 660 FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 719

Query: 478 LLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPG 536
             GPKG  G PG  G  G  G  G+ G SGP G  G  GP+G+ G  G  G  G  G  G
Sbjct: 720 RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 779

Query: 537 VAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVK 596
             G HGPPG+ G  GPQG  G PGP GPPGPPG    +P  P  +GE      +G  G  
Sbjct: 780 GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG-LPGHPGQRGE------VGFQG-- 830

Query: 597 PPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
                  K G  G P    P   A  T P    G P
Sbjct: 831 -------KTGPPGPPGVVGPQGAAGETGPMGERGHP 859



 Score =  374 bits (961), Expect = e-103
 Identities = 232/517 (44%), Positives = 263/517 (50%), Gaps = 70/517 (13%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGVGKP-GMPGMPGKPGAMGMP 175
            G  GP G PG  GP GPPG  G  G+PG KG  GP G  GV  P G+PG  G PG  G  
Sbjct: 938  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 997

Query: 176  GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGLPGQPGP---------KGDR 225
            G KGE+G  G+ G  G  G  GPPGP G  G +G+PG  G  G+PG          KGD 
Sbjct: 998  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057

Query: 226  GPKGLPGP------QGLRGPKGDKG-------FGMPGAPGVKGPPGMHGPPGPVGLPG-- 270
            G +G  GP      QGL GP G+KG        G PG PG +GP G +G  GP G PG  
Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1117

Query: 271  --------------VGKPGVTGFPGPQGPLGK------PGAPGEPGPQGPIGVPGVQGPP 310
                           G PG+ G PG +GP G+       G PGEPGP GP G  G  GP 
Sbjct: 1118 GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPK 1177

Query: 311  GIPG-IGKPGQDGIPGQPG---FPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMG 365
            G PG +G PG  G PG+ G     G KG++G  G PG PG PG  G+ G PGP G RG  
Sbjct: 1178 GNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1237

Query: 366  GVPGA------LGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV 419
            G PG+       G +G+ G IGAPG  GP G  G  G PGP G  G  G  G +G  G  
Sbjct: 1238 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1297

Query: 420  GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLL 479
            G  GPPGP G PGL G  G  G  GE G PG+ GL GP G +GE G +G+PG  G PG  
Sbjct: 1298 GQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1357

Query: 480  GPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAG 539
            G  G PG  G  G  GPPG+PG  GP G  G  G  GPKGE G+ GPPG P  G PG   
Sbjct: 1358 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP--GPPGEVI 1415

Query: 540  LHGPPGKP--------GALGPQGQPGLP--GPPGPPG 566
               P   P        G+   Q    +P  G PG PG
Sbjct: 1416 QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 38/115 (33%), Positives = 48/115 (41%), Gaps = 11/115 (9%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGK 159
            G +  P +  E+ +    G  GP G PG  GP GP G  G   PG     GP+G  GV  
Sbjct: 1349 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG-----GPKGEKGV-- 1401

Query: 160  PGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPG 214
             G PG PG PG +  P       Q  +     + G +       +P  G PG PG
Sbjct: 1402 QGPPGHPGPPGEVIQPLPI----QMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  418 bits (1074), Expect = e-116
 Identities = 283/699 (40%), Positives = 320/699 (45%), Gaps = 124/699 (17%)

Query: 55   GQQVPHMPLAKDGLAMGKEMPHLQYGKE---YPHLPQYMKEIQPAPRMGKEAVPKKGKEI 111
            G+  P  P  + G       P L   K     P LP Y     P   +G    P    E 
Sbjct: 659  GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 718

Query: 112  PLASLRGEQGPRGEPGPRGPPGPPGLPG----------------HGIPGIKGKPGPQGYP 155
                L G+ GPRGE GP GP G  G  G                HG PG +G PGPQG  
Sbjct: 719  GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 778

Query: 156  GV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGP 213
            G  G  G PG PGK G  G PG +GE+G +G+ GP G PG  GP G  G  G +G+ G P
Sbjct: 779  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 838

Query: 214  GLPGQPGP------------KGDRGPKGLPG---PQGLRGPKGDKGF-GMPGAPGVKGPP 257
            G PG PG             KGD GP G PG   P GLRG  G++G  G  G PG+KG  
Sbjct: 839  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 898

Query: 258  GMHGPPGPVGLPG----------VGKPGVTGFPGPQGPLGKPGAPGEPGP---------Q 298
            G  GPPGP G PG          +G PG  G  GP G  G+ G PGE GP         Q
Sbjct: 899  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958

Query: 299  GPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGP------PGLPGI- 350
            GP+G+PG  GPPG+ G  G  G+ G PGQ G  G KGE G PG PGP      PG  G  
Sbjct: 959  GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018

Query: 351  GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410
            G+PG  GP+G  G  G  G  G  G  GPIG  G+ GP GE G  G  GPMGPPG  G  
Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078

Query: 411  GPKGEGGIVGPQGPPG---------PKGEPGLQGFPG------------------KPGFL 443
            GP G  G  GPQGPPG          KGEPG  G PG                  + G  
Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1138

Query: 444  GEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIG 503
            GE GPPG +G  G  GPKG  G  G PG PG PG  GP+G+ G  GD+G  G PG PG  
Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1198

Query: 504  GPSGPIGPPGI------------------PGPKGEPGLPGPPGFPG-------IGKPGVA 538
            GP+G  GPPG                    G KG+PG  G PG  G        GKPG  
Sbjct: 1199 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1258

Query: 539  GLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPP 598
            GL G PG  G  G  G  G  GPPGP GPPG P +         +  P + +G+ G  PP
Sbjct: 1259 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL-IGLIG--PP 1315

Query: 599  HAYGAK-----KGKNGGPAYEMPAFTAELTAPFPPVGAP 632
               G K      G  G P  +        + P  P G P
Sbjct: 1316 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1354



 Score =  416 bits (1070), Expect = e-116
 Identities = 265/643 (41%), Positives = 296/643 (46%), Gaps = 146/643 (22%)

Query: 116  LRGEQGPRGEPGPRGPPGPPG---LPGH----GIPGIKGKPGPQGYPGV----------- 157
            L G QGP G PGP+GPPGPPG   LPGH    G  G +GK GP G PGV           
Sbjct: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 830

Query: 158  --GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKPG 211
              G+ G PG PG PG  G+PG  G+ G KG+ GP G PG  GP G  G PG     G  G
Sbjct: 831  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 890

Query: 212  GPGLPGQPGPKGDRGPKGLPG------------PQGLRGPKGDKGF----GMPGAPGVKG 255
            GPGL G  GP G  GP G PG            P G  GP+G  G     G+PG  G  G
Sbjct: 891  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 950

Query: 256  PPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGA------------PGEPGPQGPIG 302
            P G  G  GPVGLPG  G PGV G  G +G +G PG             PG PGP GP+G
Sbjct: 951  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1010

Query: 303  VPGVQGPPGIPGI-------------------GKPGQDGIPGQPGFPGGKGEQGLPGLPG 343
             PG  G  G PG                    G PG  G+ G PG  G KGE G  G  G
Sbjct: 1011 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1070

Query: 344  PPGLPG-------------------IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPG 384
            PPG PG                   +G  G PG KG+ G  G PG  G  G KGP G  G
Sbjct: 1071 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1130

Query: 385  IGGPPGEPGLPGIPGPMGP---------PGAIGFPG---PKGEGGIVGPQGPPGPKGEPG 432
              G  G+PG PG PGP GP         PG +GFPG   P GEGG  G  G  G +GE G
Sbjct: 1131 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG 1190

Query: 433  LQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG------------ 480
              G PG PG  GE GPPG  G  GP G  G  G++G  G  G PG +G            
Sbjct: 1191 EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1250

Query: 481  PKGEPG------IPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-- 532
            P G+PG      +PG  G QG PG  G  GP GP+GPPG+PG +G+ G  G  G PG+  
Sbjct: 1251 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1310

Query: 533  --------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEY 584
                    G+ G  GL GP G PG  G  G PG  GP GP GPPG P    P        
Sbjct: 1311 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK------- 1363

Query: 585  LPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFP 627
                  G  G   P     +KG  G P +  P    E+  P P
Sbjct: 1364 ------GAKGATGPGGPKGEKGVQGPPGH--PGPPGEVIQPLP 1398



 Score =  416 bits (1068), Expect = e-116
 Identities = 250/550 (45%), Positives = 284/550 (51%), Gaps = 53/550 (9%)

Query: 110  EIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG-VGKPGMPGMPGK 168
            EI    L GE GPRG  GP+GPPG PG P  G+ G+ G  GP+G  G  G+PG PG  G 
Sbjct: 489  EIGPRGLPGESGPRGLLGPKGPPGIPGPP--GVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546

Query: 169  PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGLPGQPGPKGDRGP 227
            PG  G+PG +G IG  GE GP G PG  G PG  G PG  GK G PG  G  GP G +GP
Sbjct: 547  PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGP 606

Query: 228  KGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPG----VGKPGVTGFPGPQ 283
             G PGP+G++G  G +  G+ G  G KG  G  G  G +G+ G    VG PG  G  GP+
Sbjct: 607  LGYPGPRGVKGVDGIR--GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 664

Query: 284  GPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLP 342
            GP G+ G  G+PGP G +G  G  G PG+PG  G+ G  G  G PGFPG  GE+G  GL 
Sbjct: 665  GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 724

Query: 343  GPPGLPG----IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP 398
            G  G  G     G  G  GP+G  G  G  G  G  G  GP G  G+ GP G  G PG  
Sbjct: 725  GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 784

Query: 399  GPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI 458
            GP GPPG  G PG  G+ G VG QG  GP G PG+    G  G  GE GP G RG PGP 
Sbjct: 785  GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV---VGPQGAAGETGPMGERGHPGPP 841

Query: 459  GPKGE---------AGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPI 509
            GP GE          G KG PG PG PG  GP G  G PG++GL G  G PG+ G  GP 
Sbjct: 842  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 901

Query: 510  GPPGIPGPKGEPGLP------GPPGFPG-IGKPGVAGLHGPPGKPGALGPQGQPGLPGPP 562
            GPPG  G  GE G        GPPG PG  G PG AG  G PG+ G +GP G+ G+ GP 
Sbjct: 902  GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV 961

Query: 563  GPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAEL 622
            G PGP GPP V                 G DG K       +KG  G      P      
Sbjct: 962  GLPGPAGPPGV----------------AGEDGDKGEVGDPGQKGTKGNKGEHGPPGP--- 1002

Query: 623  TAPFPPVGAP 632
              P  PVG P
Sbjct: 1003 PGPIGPVGQP 1012



 Score =  408 bits (1049), Expect = e-114
 Identities = 288/748 (38%), Positives = 330/748 (44%), Gaps = 173/748 (23%)

Query: 32  GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMK 91
           G +  P    P    + PQ QP     P     +   A G      + G+     P  + 
Sbjct: 231 GQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLV 290

Query: 92  EIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPG------ 144
           E  P P      +   G       ++G  GP G+PG RGPPG  GLPG  G PG      
Sbjct: 291 EGPPGPEGPAGLIGPPG-------IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 343

Query: 145 ----------------------------------IKGKPGPQGYPG----VGKPGMPGMP 166
                                             ++G PGP GY G    +G+PG PG+ 
Sbjct: 344 MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 403

Query: 167 GKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-------IGKPGGPGLPGQP 219
           G+ G +G  G +G  G  G  G  G  G  G  G  G+PG        G  G PGLPG+ 
Sbjct: 404 GESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK 463

Query: 220 GPKGDRGPKGLPGPQGLRGPKGDKG-FGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTG 278
           G +GD G +GLPGP G  G +GD G  G  G PG  GP G+ GP GP G+P  G PGV G
Sbjct: 464 GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP--GPPGVRG 521

Query: 279 FPGPQ------GPLGKPGAPGE---------PGPQGPIGVPGVQGPPGIPGI-GKPGQDG 322
             GPQ      GP G+PG PG+         PGPQG IG  G +GP G PG+ G PG DG
Sbjct: 522 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581

Query: 323 IPGQPGF---PGGKGEQGLPGLPGPPGLPG-------------------IGKPGFP---- 356
            PG PG    PG KG QG  G  GP G PG                    G+ GFP    
Sbjct: 582 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 641

Query: 357 --GPKGDRGMGGVPGAL------GPRGEKGPIGAPGIGGPPGE------PGLPGIPGPMG 402
             G KGDRG  GVPG+       GP+G  GP G PG  G  GE      PGLPG PG  G
Sbjct: 642 DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG 701

Query: 403 PPGAIGFP------------------GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLG 444
           P G++GFP                  GP+GE G  GP+G  GP+G  G  G  G  G  G
Sbjct: 702 PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDG 761

Query: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG 504
             GPPG RGLPGP GP G  G KG PG PG  GL G  G+ G  G QG  GPPG PG+ G
Sbjct: 762 PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 821

Query: 505 PSGPIGP---------PGIPGPKGEPGL------------PGPPGFPGIGKPGVAGLHGP 543
           P G  G          PG PGP GE GL            PGPPG P  GK G AGL G 
Sbjct: 822 PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP--GKDGPAGLRGF 879

Query: 544 PGKPGALGPQGQPGLPGPPGPPGPPGP--------------PAVMPPTPPPQGEYLPDMG 589
           PG+ G  G  G PGL G  GP GPPGP              P   P  P PQG       
Sbjct: 880 PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 939

Query: 590 LGIDGVKPPHAYGAKKGKNGGPAYEMPA 617
            G+ G K P     + G  G      PA
Sbjct: 940 KGVPGEKGPIGPTGRDGVQGPVGLPGPA 967



 Score =  374 bits (961), Expect = e-103
 Identities = 232/517 (44%), Positives = 263/517 (50%), Gaps = 70/517 (13%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGVGKP-GMPGMPGKPGAMGMP 175
            G  GP G PG  GP GPPG  G  G+PG KG  GP G  GV  P G+PG  G PG  G  
Sbjct: 917  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 976

Query: 176  GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGLPGQPGP---------KGDR 225
            G KGE+G  G+ G  G  G  GPPGP G  G +G+PG  G  G+PG          KGD 
Sbjct: 977  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036

Query: 226  GPKGLPGP------QGLRGPKGDKG-------FGMPGAPGVKGPPGMHGPPGPVGLPG-- 270
            G +G  GP      QGL GP G+KG        G PG PG +GP G +G  GP G PG  
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1096

Query: 271  --------------VGKPGVTGFPGPQGPLGK------PGAPGEPGPQGPIGVPGVQGPP 310
                           G PG+ G PG +GP G+       G PGEPGP GP G  G  GP 
Sbjct: 1097 GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPK 1156

Query: 311  GIPG-IGKPGQDGIPGQPG---FPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMG 365
            G PG +G PG  G PG+ G     G KG++G  G PG PG PG  G+ G PGP G RG  
Sbjct: 1157 GNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1216

Query: 366  GVPGA------LGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV 419
            G PG+       G +G+ G IGAPG  GP G  G  G PGP G  G  G  G +G  G  
Sbjct: 1217 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1276

Query: 420  GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLL 479
            G  GPPGP G PGL G  G  G  GE G PG+ GL GP G +GE G +G+PG  G PG  
Sbjct: 1277 GQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1336

Query: 480  GPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAG 539
            G  G PG  G  G  GPPG+PG  GP G  G  G  GPKGE G+ GPPG P  G PG   
Sbjct: 1337 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP--GPPGEVI 1394

Query: 540  LHGPPGKP--------GALGPQGQPGLP--GPPGPPG 566
               P   P        G+   Q    +P  G PG PG
Sbjct: 1395 QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431



 Score =  340 bits (873), Expect = 2e-93
 Identities = 231/629 (36%), Positives = 281/629 (44%), Gaps = 146/629 (23%)

Query: 117 RGEQGPRGEPGPRGPPG---PPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMG 173
           R ++ P+ +P     P    P     HG  G+KG+   +G P V +PGM  + G PG  G
Sbjct: 243 RAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGE---KGEPAVLEPGML-VEGPPGPEG 298

Query: 174 MPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPK----------- 222
             G  G  G +G  GP+G PG +GPPG  GLPG       G PG PG             
Sbjct: 299 PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPG-----SDGAPGPPGTSLMLPFRFGSGG 353

Query: 223 GDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPG 281
           GD+GP         +         + G PG  G  G  GP G  G PG+ G+ G  G  G
Sbjct: 354 GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQG 413

Query: 282 PQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPG 340
           P+GP G  G PG+ G +G  G  G +G PG PG+ G  G DG+PG PG  G +G+ G  G
Sbjct: 414 PRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQG 473

Query: 341 LPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGL------ 394
           LPGPPG     + G  G  G+ G  G+PG  GPRG  GP G PGI GPPG  G+      
Sbjct: 474 LPGPPG-----EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528

Query: 395 ---------PGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGK---PGF 442
                    PG PG  G PG  G PGP+G    +GP G  GP+G+PGL G PG    PG 
Sbjct: 529 KGSLGPQGEPGPPGQQGTPGTQGLPGPQGA---IGPHGEKGPQGKPGLPGMPGSDGPPGH 585

Query: 443 LGEVGPPGMRGLPGPIGP------------------------KGEAGQKGVPGLPGVPGL 478
            G+ GPPG +G  GP GP                        KGE G+ G PG  G  G+
Sbjct: 586 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 645

Query: 479 LGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG------- 531
            G +GE G+PG +G  GP G  G  GP+G  GPPG+ G KG+ G+PG PG+PG       
Sbjct: 646 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 705

Query: 532 IGKPGVAGL------------------------------------------------HGP 543
           +G PG  G                                                 HGP
Sbjct: 706 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP 765

Query: 544 PGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGA 603
           PG+ G  GPQG  G PGP GPPGPPG    +P  P  +GE      +G  G         
Sbjct: 766 PGERGLPGPQGPNGFPGPKGPPGPPGKDG-LPGHPGQRGE------VGFQG--------- 809

Query: 604 KKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
           K G  G P    P   A  T P    G P
Sbjct: 810 KTGPPGPPGVVGPQGAAGETGPMGERGHP 838



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 38/115 (33%), Positives = 48/115 (41%), Gaps = 11/115 (9%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGK 159
            G +  P +  E+ +    G  GP G PG  GP GP G  G   PG     GP+G  GV  
Sbjct: 1328 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG-----GPKGEKGV-- 1380

Query: 160  PGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPG 214
             G PG PG PG +  P       Q  +     + G +       +P  G PG PG
Sbjct: 1381 QGPPGHPGPPGEVIQPLPI----QMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  418 bits (1074), Expect = e-116
 Identities = 283/699 (40%), Positives = 320/699 (45%), Gaps = 124/699 (17%)

Query: 55   GQQVPHMPLAKDGLAMGKEMPHLQYGKE---YPHLPQYMKEIQPAPRMGKEAVPKKGKEI 111
            G+  P  P  + G       P L   K     P LP Y     P   +G    P    E 
Sbjct: 766  GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 825

Query: 112  PLASLRGEQGPRGEPGPRGPPGPPGLPG----------------HGIPGIKGKPGPQGYP 155
                L G+ GPRGE GP GP G  G  G                HG PG +G PGPQG  
Sbjct: 826  GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 885

Query: 156  GV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGP 213
            G  G  G PG PGK G  G PG +GE+G +G+ GP G PG  GP G  G  G +G+ G P
Sbjct: 886  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 945

Query: 214  GLPGQPGP------------KGDRGPKGLPG---PQGLRGPKGDKGF-GMPGAPGVKGPP 257
            G PG PG             KGD GP G PG   P GLRG  G++G  G  G PG+KG  
Sbjct: 946  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 1005

Query: 258  GMHGPPGPVGLPG----------VGKPGVTGFPGPQGPLGKPGAPGEPGP---------Q 298
            G  GPPGP G PG          +G PG  G  GP G  G+ G PGE GP         Q
Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 1065

Query: 299  GPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGP------PGLPGI- 350
            GP+G+PG  GPPG+ G  G  G+ G PGQ G  G KGE G PG PGP      PG  G  
Sbjct: 1066 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1125

Query: 351  GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410
            G+PG  GP+G  G  G  G  G  G  GPIG  G+ GP GE G  G  GPMGPPG  G  
Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185

Query: 411  GPKGEGGIVGPQGPPG---------PKGEPGLQGFPG------------------KPGFL 443
            GP G  G  GPQGPPG          KGEPG  G PG                  + G  
Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1245

Query: 444  GEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIG 503
            GE GPPG +G  G  GPKG  G  G PG PG PG  GP+G+ G  GD+G  G PG PG  
Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSP 1305

Query: 504  GPSGPIGPPGI------------------PGPKGEPGLPGPPGFPG-------IGKPGVA 538
            GP+G  GPPG                    G KG+PG  G PG  G        GKPG  
Sbjct: 1306 GPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1365

Query: 539  GLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPP 598
            GL G PG  G  G  G  G  GPPGP GPPG P +         +  P + +G+ G  PP
Sbjct: 1366 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL-IGLIG--PP 1422

Query: 599  HAYGAK-----KGKNGGPAYEMPAFTAELTAPFPPVGAP 632
               G K      G  G P  +        + P  P G P
Sbjct: 1423 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1461



 Score =  416 bits (1070), Expect = e-116
 Identities = 265/643 (41%), Positives = 296/643 (46%), Gaps = 146/643 (22%)

Query: 116  LRGEQGPRGEPGPRGPPGPPG---LPGH----GIPGIKGKPGPQGYPGV----------- 157
            L G QGP G PGP+GPPGPPG   LPGH    G  G +GK GP G PGV           
Sbjct: 878  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 937

Query: 158  --GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI----GKPG 211
              G+ G PG PG PG  G+PG  G+ G KG+ GP G PG  GP G  G PG     G  G
Sbjct: 938  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 997

Query: 212  GPGLPGQPGPKGDRGPKGLPG------------PQGLRGPKGDKGF----GMPGAPGVKG 255
            GPGL G  GP G  GP G PG            P G  GP+G  G     G+PG  G  G
Sbjct: 998  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 1057

Query: 256  PPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGA------------PGEPGPQGPIG 302
            P G  G  GPVGLPG  G PGV G  G +G +G PG             PG PGP GP+G
Sbjct: 1058 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1117

Query: 303  VPGVQGPPGIPGI-------------------GKPGQDGIPGQPGFPGGKGEQGLPGLPG 343
             PG  G  G PG                    G PG  G+ G PG  G KGE G  G  G
Sbjct: 1118 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1177

Query: 344  PPGLPG-------------------IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPG 384
            PPG PG                   +G  G PG KG+ G  G PG  G  G KGP G  G
Sbjct: 1178 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1237

Query: 385  IGGPPGEPGLPGIPGPMGP---------PGAIGFPG---PKGEGGIVGPQGPPGPKGEPG 432
              G  G+PG PG PGP GP         PG +GFPG   P GEGG  G  G  G +GE G
Sbjct: 1238 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG 1297

Query: 433  LQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG------------ 480
              G PG PG  GE GPPG  G  GP G  G  G++G  G  G PG +G            
Sbjct: 1298 EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1357

Query: 481  PKGEPG------IPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-- 532
            P G+PG      +PG  G QG PG  G  GP GP+GPPG+PG +G+ G  G  G PG+  
Sbjct: 1358 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1417

Query: 533  --------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEY 584
                    G+ G  GL GP G PG  G  G PG  GP GP GPPG P    P        
Sbjct: 1418 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK------- 1470

Query: 585  LPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFP 627
                  G  G   P     +KG  G P +  P    E+  P P
Sbjct: 1471 ------GAKGATGPGGPKGEKGVQGPPGH--PGPPGEVIQPLP 1505



 Score =  405 bits (1042), Expect = e-113
 Identities = 268/664 (40%), Positives = 304/664 (45%), Gaps = 166/664 (25%)

Query: 116  LRGEQGPRGEPGPRGPPGPPGLPGH-GIPG------------------------------ 144
            ++G  GP G+PG RGPPG  GLPG  G PG                              
Sbjct: 415  IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA 474

Query: 145  ----------IKGKPGPQGYPG----VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPM 190
                      ++G PGP GY G    +G+PG PG+ G+ G +G  G +G  G  G  G  
Sbjct: 475  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKA 534

Query: 191  GIPGPQGPPGPHGLPGI-------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDK 243
            G  G  G  G  G+PG        G  G PGLPG+ G +GD G +GLPGP G  G +GD 
Sbjct: 535  GRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 594

Query: 244  G-FGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302
            G  G  G PG  GP G+ GP GP G+PG   PGV G  GPQGP G  G  GEPGP G  G
Sbjct: 595  GEIGPRGLPGESGPRGLLGPKGPPGIPG--PPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 652

Query: 303  VPGVQGPPGIPGI----------GKPGQDGIPGQPGFPGGKGEQGLPGL----------- 341
             PG QG PG  G           GKPG  G+PG  G PG  G++G PG            
Sbjct: 653  TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712

Query: 342  ----PGPPGLPGI-------------GKPGFPG------PKGDRGMGGVPGAL------G 372
                PGP G+ G+             G+ GFPG       KGDRG  GVPG+       G
Sbjct: 713  PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 772

Query: 373  PRGEKGPIGAPGIGGPPGE------PGLPGIPGPMGPPGAIGFP---------------- 410
            P+G  GP G PG  G  GE      PGLPG PG  GP G++GFP                
Sbjct: 773  PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG 832

Query: 411  --GPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG 468
              GP+GE G  GP+G  GP+G  G  G  G  G  G  GPPG RGLPGP GP G  G KG
Sbjct: 833  KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG 892

Query: 469  VPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGP---------PGIPGPKG 519
             PG PG  GL G  G+ G  G QG  GPPG PG+ GP G  G          PG PGP G
Sbjct: 893  PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG 952

Query: 520  EPGL------------PGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGP 567
            E GL            PGPPG P  GK G AGL G PG+ G  G  G PGL G  GP GP
Sbjct: 953  EQGLPGTAGKEGTKGDPGPPGAP--GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 1010

Query: 568  PGP--------------PAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAY 613
            PGP              P   P  P PQG        G+ G K P     + G  G    
Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 1070

Query: 614  EMPA 617
              PA
Sbjct: 1071 PGPA 1074



 Score =  385 bits (988), Expect = e-106
 Identities = 268/689 (38%), Positives = 318/689 (46%), Gaps = 143/689 (20%)

Query: 36  LPP----QIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMK 91
           LPP    Q   Q+PP   ++Q           A++    G + P   Y   Y +   Y +
Sbjct: 308 LPPLEEEQTDLQVPPTADRFQ-----------AEEYGEGGTDPPEGPYDYTYGYGDDYRE 356

Query: 92  EIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPG--PPGLPGHGIPGIKGKP 149
           E +  P +  E            S     GPRG  G +G P    PG+       ++G P
Sbjct: 357 ETELGPALSAETAH---------SGAAAHGPRGLKGEKGEPAVLEPGML------VEGPP 401

Query: 150 GPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP-------------- 195
           GP+G  G+  P  PG+ G PG +G PG +G  G+ G  G  G PGP              
Sbjct: 402 GPEGPAGLIGP--PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG 459

Query: 196 --------------------------QGPPGPHGLPG----IGKPGGPGLPGQP---GPK 222
                                     +GPPGP G  G    +G+PG PGL G+    GP+
Sbjct: 460 GGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ 519

Query: 223 GDRGPKGLPGPQGLRGPKG----DKGFGMPGAPGVKGPPGMHGPPGPVGLPG-VGKPGVT 277
           G RGP+GL GP G  G +G    D   GMPG PGVKG  G  G P   GLPG  G  G T
Sbjct: 520 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP---GLPGEKGHRGDT 576

Query: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQG 337
           G  G  GP G+ G  G+ G  GP G+PG  GP G+  +G  G  GIPG PG  G  G QG
Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL--LGPKGPPGIPGPPGVRGMDGPQG 634

Query: 338 LPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGI 397
             G  GP G P  G PG  G  G +G+ G  GA+GP GEKGP G PG+ G PG  G PG 
Sbjct: 635 PKGSLGPQGEP--GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 692

Query: 398 P------------GPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFL-- 443
           P            GP GP G +G+PGP+G  G+ G +G  G KGE G  GFPG  G +  
Sbjct: 693 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 752

Query: 444 ----GEVGPPGMRGLPGPIGPK---------------GEAGQKGVPGLPGVPGLLGPKGE 484
               GEVG PG RG  GP GPK               GE G+ GVPGLPG PG  GPKG 
Sbjct: 753 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 812

Query: 485 PGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHGP 543
            G PG  G  G  G  G+ G SGP G  G  GP+G+ G  G  G  G  G  G  G HGP
Sbjct: 813 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP 872

Query: 544 PGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGA 603
           PG+ G  GPQG  G PGP GPPGPPG    +P  P  +GE      +G  G         
Sbjct: 873 PGERGLPGPQGPNGFPGPKGPPGPPGKDG-LPGHPGQRGE------VGFQG--------- 916

Query: 604 KKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
           K G  G P    P   A  T P    G P
Sbjct: 917 KTGPPGPPGVVGPQGAAGETGPMGERGHP 945



 Score =  374 bits (961), Expect = e-103
 Identities = 232/517 (44%), Positives = 263/517 (50%), Gaps = 70/517 (13%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGVGKP-GMPGMPGKPGAMGMP 175
            G  GP G PG  GP GPPG  G  G+PG KG  GP G  GV  P G+PG  G PG  G  
Sbjct: 1024 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 1083

Query: 176  GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGLPGQPGP---------KGDR 225
            G KGE+G  G+ G  G  G  GPPGP G  G +G+PG  G  G+PG          KGD 
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143

Query: 226  GPKGLPGP------QGLRGPKGDKG-------FGMPGAPGVKGPPGMHGPPGPVGLPG-- 270
            G +G  GP      QGL GP G+KG        G PG PG +GP G +G  GP G PG  
Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1203

Query: 271  --------------VGKPGVTGFPGPQGPLGK------PGAPGEPGPQGPIGVPGVQGPP 310
                           G PG+ G PG +GP G+       G PGEPGP GP G  G  GP 
Sbjct: 1204 GNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPK 1263

Query: 311  GIPG-IGKPGQDGIPGQPG---FPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMG 365
            G PG +G PG  G PG+ G     G KG++G  G PG PG PG  G+ G PGP G RG  
Sbjct: 1264 GNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1323

Query: 366  GVPGA------LGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV 419
            G PG+       G +G+ G IGAPG  GP G  G  G PGP G  G  G  G +G  G  
Sbjct: 1324 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1383

Query: 420  GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLL 479
            G  GPPGP G PGL G  G  G  GE G PG+ GL GP G +GE G +G+PG  G PG  
Sbjct: 1384 GQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1443

Query: 480  GPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAG 539
            G  G PG  G  G  GPPG+PG  GP G  G  G  GPKGE G+ GPPG P  G PG   
Sbjct: 1444 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHP--GPPGEVI 1501

Query: 540  LHGPPGKP--------GALGPQGQPGLP--GPPGPPG 566
               P   P        G+   Q    +P  G PG PG
Sbjct: 1502 QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 38/115 (33%), Positives = 48/115 (41%), Gaps = 11/115 (9%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGK 159
            G +  P +  E+ +    G  GP G PG  GP GP G  G   PG     GP+G  GV  
Sbjct: 1435 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG-----GPKGEKGV-- 1487

Query: 160  PGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPG 214
             G PG PG PG +  P       Q  +     + G +       +P  G PG PG
Sbjct: 1488 QGPPGHPGPPGEVIQPLPI----QMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  417 bits (1073), Expect = e-116
 Identities = 276/632 (43%), Positives = 321/632 (50%), Gaps = 98/632 (15%)

Query: 86   LPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGI 145
            LP   +   P    G++  P K   I     RG +G RG+PGP+GPPG          G 
Sbjct: 1971 LPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGL-------ALGE 2023

Query: 146  KGKPGPQGYPG-VGKPGMPGMP---------GKPGAMGMPGAKGEIGQKGEIGPMGIPGP 195
            +G PGP G  G  GKPG+PG+P         G+PG  G  G KGE G++G  GP G+PG 
Sbjct: 2024 RGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGT 2083

Query: 196  QGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKG 255
             GPPGP G        GPGL G+ GP G +G KG PG  G +GPKGD+  G+PG  G +G
Sbjct: 2084 PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDR--GVPGIKGDRG 2141

Query: 256  PPGMHGPPGPVGLPG-------VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQG 308
             PG  G  G  GLPG        GKPG+ G  GP GP+G  G PG PG  G  G  G QG
Sbjct: 2142 EPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQG 2201

Query: 309  PPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGP---------PGLPG----IGKPGF 355
            P G+   G+PG+ G PG+ G  G  G  GLPG PGP         PGLPG     GKPG 
Sbjct: 2202 PSGLK--GEPGETGPPGR-GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGA 2258

Query: 356  P------GPKGDRGMGGVPGA------LGPRGEKGPIGAPG--IGGPPGEPGLPGIPGPM 401
            P      G  GDRG  GVPG+      +GP+GE GP GAPG  + G PG  G  G PG +
Sbjct: 2259 PGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGL 2318

Query: 402  -----GPPGA---IGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE--VGPPGM 451
                 G PGA    G PGP+GE G  G  G PG  GE G +G PG  GF G+  VG PG 
Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS 2378

Query: 452  RGLPGPIGPKGEAGQKGVPGLPGV---PGLLGPKGE---PGIPGDQGLQGPPGIPGIGGP 505
             G PGP G KG+ G  G+PG PGV   PG  GP+GE   PG  G++GL GPPG  GI GP
Sbjct: 2379 PGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGP 2438

Query: 506  SGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPP---GKPGALGPQGQPGLPGPP 562
             GP GPPG  GP G  GL G  G PG+G PG  G  G P   G+ G  G +G  GL GPP
Sbjct: 2439 LGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPP 2498

Query: 563  GP---------------PGPPGPPAVMPPTPPPQGEYLPDMG----LGIDGVKPPHAYG- 602
            G                 G  G  AV+   P P+G    DMG     G+DG K P     
Sbjct: 2499 GSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGA-KGDMGERGPRGLDGDKGPRGDNG 2557

Query: 603  --AKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632
                KG  G P  +  A    L     P G P
Sbjct: 2558 DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQP 2589



 Score =  407 bits (1045), Expect = e-113
 Identities = 262/625 (41%), Positives = 304/625 (48%), Gaps = 136/625 (21%)

Query: 112  PLASLRGEQGPRGEPGPRGPPGPPGLPG----HGIPGIKGKPGPQGYPGV---------- 157
            P A  +GE G RG+ GPRGP G PGLPG     GI G +G PGPQG PGV          
Sbjct: 1713 PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDR 1772

Query: 158  GKPGMPG---MPGKPGAMGMPGAKGEIGQKGEIG---------PMGIPGPQGPPGPHGLP 205
            G PG+ G   + GKPGA G  G  G  G+ G+ G           G+PGP GPPG  G P
Sbjct: 1773 GPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKP 1832

Query: 206  GI-------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPG 258
            G        GK G PG PG+ G KG++G  G  G +G  GPKG++G     APG+ GP G
Sbjct: 1833 GEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERG-----APGILGPQG 1887

Query: 259  MHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPG---------------------- 296
              G PGPVG PG G PGV G  GP+G  G+ G+ GE G                      
Sbjct: 1888 PPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLE 1947

Query: 297  -----------------------------PQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQ 326
                                          +GP G  G QGPPG  G IG PG+ G+ G 
Sbjct: 1948 TAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGD 2007

Query: 327  PGFPGGKGEQGLP----------GLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGE 376
             G PG +G  GL           GL G PG PGI  PG PG  G  G  G PG  G RGE
Sbjct: 2008 RGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGI--PGLPGRAGGVGEAGRPGERGERGE 2065

Query: 377  KGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGF 436
            KG  G  G  GPPG PG PG PGP GP  ++  PGP    G+ G QGPPG KG  G  G 
Sbjct: 2066 KGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP----GLSGEQGPPGLKGAKGEPGS 2121

Query: 437  PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV------PGLLGPKGEPGIPGD 490
             G  G  G+ G PG++G  G  GP+G+ G  G+PG  G+      PGL GP+G PG  G 
Sbjct: 2122 NGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGG 2181

Query: 491  QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGAL 550
             G  GPPG PG+ GP+GP GP G+   KGEPG  GPPG    G  G  GL GPPG  G +
Sbjct: 2182 HGDPGPPGAPGLAGPAGPQGPSGL---KGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLV 2238

Query: 551  GPQGQPGLPGPPGPPGPPGPPA--------------------VMPPTPPPQGEYLPDMGL 590
            GPQG PGLPG  G  G PG P                      +P    P+GE  P    
Sbjct: 2239 GPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP 2298

Query: 591  GIDGVKPPHAYGAKKGKNGGPAYEM 615
            G   V  P A G +KG  GG A ++
Sbjct: 2299 GQAVVGLPGAKG-EKGAPGGLAGDL 2322



 Score =  405 bits (1040), Expect = e-113
 Identities = 273/704 (38%), Positives = 316/704 (44%), Gaps = 208/704 (29%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPG----------HGIPGIKGKPGPQGYPGV----GKPGMP 163
            G  GP G  G  G PG  GLPG           G PG+ GKPG  G PG+    G+PG P
Sbjct: 1791 GPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDP 1850

Query: 164  GMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGG--PGLPGQPG 220
            G  G+ G  G  GA G  G+ G  G  G PG  GP GP GLPG +G PG   PG+PG  G
Sbjct: 1851 GEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTG 1910

Query: 221  PKGDRGP------KGLPGPQGLRG------------------------------------ 238
            PKGDRG       +GLPG +GLRG                                    
Sbjct: 1911 PKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSF 1970

Query: 239  ---------PKGDKG----------FGMPGA---------PGVKGPPGM----HGPPGPV 266
                     PKGD G           G PG          PG +GPPG+     GPPGP 
Sbjct: 1971 LPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPS 2030

Query: 267  GLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQG------------PIGVPGVQGPPGIP 313
            GL G  GKPG+ G PG  G +G+ G PGE G +G            P G+PG  GPPG P
Sbjct: 2031 GLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPP 2090

Query: 314  GI---------------GKPGQDGIPGQPGFPGG---KGEQGLPGLPGPPGLPGI----G 351
            G                G PG  G  G+PG  G    KG++G+PG+ G  G PG     G
Sbjct: 2091 GPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDG 2150

Query: 352  KPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPG------ 405
             PG PG +G  G  G PG  GPRG  GP+G  G  GPPG PGL G  GP GP G      
Sbjct: 2151 NPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPG 2210

Query: 406  --------------AIGFPGPKGEGGIVGPQGPPGPKGE---------PGLQGFPGKPGF 442
                          A+G PGP G  G+VGPQG PG  G+         PG  G  GK G 
Sbjct: 2211 ETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGD 2270

Query: 443  LGEVGPPGMRGLPGPIGPKGEAGQKGVPG--LPGVPGLLGPKG-----------EPGIPG 489
             G  G PG  GLPGP+GPKGE G  G PG  + G+PG  G KG           EPG  G
Sbjct: 2271 RGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKG 2330

Query: 490  DQGLQGP------------------------------PGIPGIGGPSGPIGPPGIPGPKG 519
            D+GL GP                               G PG+G P  P GPPG PG KG
Sbjct: 2331 DRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSP-GPPGPPGVKG 2389

Query: 520  EPGLPGPPGFPGI-------GKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPA 572
            + GLPG PG PG+       G  G  G  GP G+ G  GP G+ G+PGP GPPGPPG  +
Sbjct: 2390 DLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPG--S 2447

Query: 573  VMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMP 616
            V PP          D G+G+ G +        +G++G P  E P
Sbjct: 2448 VGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGP 2491



 Score =  400 bits (1029), Expect = e-111
 Identities = 266/618 (43%), Positives = 313/618 (50%), Gaps = 113/618 (18%)

Query: 87   PQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGI 145
            P  +K  +  P    +  PK  + +P     G +G RGEPGPRG  G PGLPG  G+ G 
Sbjct: 2109 PPGLKGAKGEPGSNGDQGPKGDRGVP-----GIKGDRGEPGPRGQDGNPGLPGERGMAGP 2163

Query: 146  KGKPG---PQGYPG-VGKPGMPGMPGKPGAMGMPGAKGEIGQKGE--------------I 187
            +GKPG   P+G PG VG  G PG PG PG  G  G +G  G KGE               
Sbjct: 2164 EGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPT 2223

Query: 188  GPMGIPGPQGPPG---PHGLPGI-------GKPGGPGLPGQPGPKGDRGPKGLPGPQGLR 237
            G +G+PGP GP G   P G PG+       GKPG PG  G  G  GDRG  G+PG  GL 
Sbjct: 2224 GAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLP 2283

Query: 238  GPKGDKGF-GMPGAPG--VKGPPGMHGPPG-PVGLPG--VGKPGVTG---FPGPQGP--- 285
            GP G KG  G  GAPG  V G PG  G  G P GL G  VG+PG  G    PGP+G    
Sbjct: 2284 GPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGE 2343

Query: 286  LGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP 345
             G+ G PG+PG  G  G PG +G  G PG+G PG    PG PG PG KG+ GLPGLPG P
Sbjct: 2344 AGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS---PGPPGPPGVKGDLGLPGLPGAP 2400

Query: 346  GLPGI-------GKPGFPGPKGDRGMGG------VPGALGPRGEKGPIGAPG-------- 384
            G+ G        G+ G PGP G+RG+ G      +PG LGP G  G +G PG        
Sbjct: 2401 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2460

Query: 385  ------IGGPPGEPGLPGI------PGPMGPPGAIGFPGPKGEGGIVGPQG--------- 423
                  + GP GE G PGI      PG  GP G  G PG +GE G  G  G         
Sbjct: 2461 GDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2520

Query: 424  -------PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP 476
                   PPGP+G  G  G  G  G  G+ GP G  G PG  G KGE G KG  GLPG+ 
Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580

Query: 477  GLLGPKGEPG---IPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIG 533
            GLLGP+G+PG   IPGD G  G  G+PGI G  G +G  G  G KGE G+ G  G  G  
Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDG-- 2638

Query: 534  KPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGID 593
            + G  G  GPPG+PG  G +G+ G PG PG  G PG   ++ P    +G+       G D
Sbjct: 2639 EKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGP----KGDR------GFD 2688

Query: 594  GVKPPHAYGAKKGKNGGP 611
            G   P     +KG+ G P
Sbjct: 2689 GQPGPKGDQGEKGERGTP 2706



 Score =  400 bits (1028), Expect = e-111
 Identities = 260/610 (42%), Positives = 304/610 (49%), Gaps = 105/610 (17%)

Query: 55   GQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAV-----PKKGK 109
            G++ P  P  + G       P    G E P LP    +  P+   G         P+   
Sbjct: 1338 GERGPRGPKGEPGA------PGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPP 1391

Query: 110  EIPLASLRGEQGPRGEPGPRGP------PGPPGLPGHGIPGIKGKPGPQGYPGV------ 157
             +P  +++G++G RGE GP GP      PG PGLPG  +PG  G  GP G PG       
Sbjct: 1392 GLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPG--LPGSPGPQGPVGPPGKKGEKGD 1449

Query: 158  ---GKPGMPGMPGKPGAMGMPGAKGEIGQKGE------IGPMGIPGPQGPPGP---HGLP 205
               G PG+PG PG PG  G  G  G IG KG+      +G  G  G +GPPGP    GLP
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509

Query: 206  GI-GKPGGPGLPGQPGPKGDRGPKGLPGPQG--------LRGPKGDKGF-------GMPG 249
            G+ G+PG  G  G PGP G +G KG PG  G        + GPKG+KG        G  G
Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATG 1569

Query: 250  APGVKGPPGM--HGPPGPVGLPG----VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGV 303
              G +GPPG+   G PGP G PG    +G  G  G PG  GP G+ G PG PGP GP+G 
Sbjct: 1570 VQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGP 1629

Query: 304  ---------PGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKP 353
                      G +GPPG PG+ GK G+ G+ G PG  G  GE+G  G PG  G  G   P
Sbjct: 1630 RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNG--SP 1687

Query: 354  GFPGPKGDRGMGGVPGALG----------PRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP 403
            G  GPKGDRG  G PG  G           +GE G  G  G  GP G+PGLPG PG  G 
Sbjct: 1688 GSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGI 1747

Query: 404  PGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQG---FPGKPGFLGEVGP---------PGM 451
             G  G PGP+G+ G+ GP G  G +G PGL G     GKPG  G  GP         PG 
Sbjct: 1748 EGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGR 1807

Query: 452  RGLPGPIGPKGEAGQKGVPGLPGVPG------LLGPKGEPGIPGDQGLQGPPGIPGIGG- 504
             GLPG  G +G  G  G PGLPG PG      L G  GEPG PG+ G +G  G  G  G 
Sbjct: 1808 DGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGR 1867

Query: 505  -----PSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLP 559
                 P G  G PGI GP+G PGLPGP G PG G PGV G  GP G  G  G +G+ GLP
Sbjct: 1868 EGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLP 1927

Query: 560  GPPGPPGPPG 569
            G  G  G PG
Sbjct: 1928 GERGLRGEPG 1937



 Score =  397 bits (1020), Expect = e-110
 Identities = 270/682 (39%), Positives = 312/682 (45%), Gaps = 137/682 (20%)

Query: 84   PHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIP 143
            P L Q +  +  A          + +  P+   +G++G  GE G RG  GPPG PG  +P
Sbjct: 1220 PSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPG--LP 1277

Query: 144  GIKGKPGPQGYPGV----------GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIP 193
            G  G PGPQG PG           G  G PG PG+ G  G PGA G  G  G  GP G P
Sbjct: 1278 GRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDP 1337

Query: 194  GPQGPPGPHGLPGI----------GKPGGPGLPGQPGPKGDRGPKGLPGPQG-------- 235
            G +GP GP G PG           G PG  G PG  GP G RGP G PGP+G        
Sbjct: 1338 GERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTA 1397

Query: 236  LRGPKGDKGFG----------MPGAPGVKGPPGMHGPPGPVGLPG------------VGK 273
            ++G KGD+G             PG PG+ G PG  GP GPVG PG             G 
Sbjct: 1398 MKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGL 1457

Query: 274  PGVTGFPGPQGPLGKPGAPGE------PGPQGPIGVPGVQGPP------GIPGI-GKPGQ 320
            PG  G PG QGP G PGA G       PGP G  G  G +GPP      G+PG+ G+PG 
Sbjct: 1458 PGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGA 1517

Query: 321  DGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPI 380
             G  G PG  G +GE+G PG PG P + G    G  G KGD G  G  GA G +GE+GP 
Sbjct: 1518 KGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPP 1577

Query: 381  GA-----PGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK------G 429
            G      PG  G PG+ G  G+ G  GPPG  G PG KG+ G  GP GP GP+      G
Sbjct: 1578 GLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVG 1637

Query: 430  EPGLQGFPGKPGFLGEVGPPGMRGLP---GPIGPKGEAGQKGVPGLPGVPGLLGPKG--- 483
            E G +G PG PG  G+ G  G+RG P   GP+G KG+ G  G  G  G PG  GPKG   
Sbjct: 1638 EKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRG 1697

Query: 484  -------------------EPGIPGDQGLQGP------PGIP---------GIGGPSGPI 509
                               E G PGD+G +GP      PG+P         G  GP GP 
Sbjct: 1698 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ 1757

Query: 510  GPPGIPGPKGEPGLPGPPGFPG----IGKPGVAGLHGP---------PGKPGALGPQGQP 556
            G PG+ GP GE G  GPPG  G     GKPG AG  GP         PG+ G  G +G+ 
Sbjct: 1758 GDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQ 1817

Query: 557  GLPGPPGPPGPPGPPAV--------MPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKN 608
            GLPGP GPPG PG P              P   GE       G  G          KG+ 
Sbjct: 1818 GLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGER 1877

Query: 609  GGPAYEMPAFTAELTAPFPPVG 630
            G P    P     L  P  P G
Sbjct: 1878 GAPGILGPQGPPGLPGPVGPPG 1899



 Score =  389 bits (998), Expect = e-108
 Identities = 275/715 (38%), Positives = 327/715 (45%), Gaps = 180/715 (25%)

Query: 117  RGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-----------------G 158
            RG +G  GE GP G  GP G PG  G+ G +G PGPQG PG+                 G
Sbjct: 1978 RGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPG 2037

Query: 159  KPGMPGMPGKPGAMG---MPGAKGEIGQKGEIG------PMGIPGPQGPPGPHGLPGIGK 209
            KPG+PG+PG+ G +G    PG +GE G+KGE G      P G+PG  GPPGP G      
Sbjct: 2038 KPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVD 2097

Query: 210  PGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF-------------------GMPGA 250
              GPGL G+ GP G +G KG PG  G +GPKGD+G                    G+PG 
Sbjct: 2098 EPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGE 2157

Query: 251  PGVKGPPGM------HGPPGPVGLPG----VGKPGVTGFPGPQGPLGKPGAPGE------ 294
             G+ GP G        GPPGPVG  G     G PG+ G  GPQGP G  G PGE      
Sbjct: 2158 RGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGR 2217

Query: 295  -----------PGPQGPIGVPGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLP 342
                       PGP GP G+ G QG PG+PG +G+ G+ G PG+ G  G  G++G PG+P
Sbjct: 2218 GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVP 2277

Query: 343  GPPGLPG-IGKPGFPGP--------------KGDRG--------MGGVPGALGPRGEKGP 379
            G PGLPG +G  G PGP              KG++G        + G PGA G RG  GP
Sbjct: 2278 GSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGP 2337

Query: 380  IGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEG--GIVGPQGPPGPKGEPGLQGFP 437
             G  G  G  GEPG PG  G  G PG  GF G  G G  G  GP GPPG KG+ GL G P
Sbjct: 2338 RGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLP 2397

Query: 438  GKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGI---PGDQGLQ 494
            G PG +G  G  G RG  G  GP GE G  G PG  G+PG LGP G PG    PG  GL+
Sbjct: 2398 GAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLK 2457

Query: 495  GPPGIPGIG--GPSGPIGPPGI------PGPKGEPGLPGPPGFPG-------IGKPGVAG 539
            G  G PG+G  GP G  G PGI      PG +G  GL GPPG  G       +G  G+ G
Sbjct: 2458 GDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKG 2517

Query: 540  -------LHGPPGKPGALGPQGQ------------------------------------P 556
                   + GPPG  GA G  G+                                    P
Sbjct: 2518 DKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLP 2577

Query: 557  GLPGPPGPPGPPGPPAVMPPTPPPQGEYLP-------DMGL-------GIDGVKPPHAYG 602
            GL G  GP G PG   +      P  + +P       D+G        G  GVK      
Sbjct: 2578 GLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLD 2637

Query: 603  AKKGKNG--GPAYE--MPAFTAELTAPFPP--VGAPVKFNKLLYNGRQNYNPQTG 651
             +KG  G  GP     +     E+  P  P   GAP K   +   G + ++ Q G
Sbjct: 2638 GEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPG 2692



 Score =  389 bits (998), Expect = e-108
 Identities = 255/638 (39%), Positives = 310/638 (48%), Gaps = 160/638 (25%)

Query: 94   QPAPRMGKEAVPKKGKEIPLASLRGE---QGPRGEPGP---RGPPGPPGLPG-------H 140
            +P PR G++  P    E  +A   G+   QGPRG PGP    G PGPPG PG        
Sbjct: 2142 EPGPR-GQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 141  GIPGIKGKPGPQGYPG---------------------VGKPGMPGMPGKPGAMGMPGAKG 179
            G  G+KG+PG  G PG                     VG  G PG+PG+ G  G PGA G
Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260

Query: 180  EIGQKGEIGPMGIPG------------PQGPPGPHGLPG--------------------- 206
              G  G+ G  G PG            P+G PGP G PG                     
Sbjct: 2261 RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAG 2320

Query: 207  --IGKPGGPGLPGQPGPKGDRGP---------------KGLPGPQGLRGPKGDKGFGMPG 249
              +G+PG  G  G PGP+G++G                KG PGP+G    KGD G G+PG
Sbjct: 2321 DLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGF---KGDPGVGVPG 2377

Query: 250  APGVKGPPGMHGPPGPVGLPGVGKPGVTGFPG---PQGPLGKPGAPGE---PGPQGPIGV 303
            +PG  GPPG+ G  G  GLPG   PGV GFPG   P+G +G+PG  GE    GP G  G+
Sbjct: 2378 SPGPPGPPGVKGDLGLPGLPGA--PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435

Query: 304  PGVQGPPGIPG-IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGD 361
            PG  GPPG PG +G PG  G+ G  G PG     GLPG  G  G PGI G+ G PG +G 
Sbjct: 2436 PGPLGPPGPPGSVGPPGASGLKGDKGDPG----VGLPGPRGERGEPGIRGEDGRPGQEGP 2491

Query: 362  RGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGP 421
            RG+ G PG+ G RGEKG +G+ G+ G  G+  +  I GP GP GA G  G +G  G+ G 
Sbjct: 2492 RGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAV--ILGPPGPRGAKGDMGERGPRGLDGD 2549

Query: 422  QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPG---VPGL 478
            +GP G  G+PG +G  G+PG  G  G PG+RGL GP G  G AG  G PG PG   VPG+
Sbjct: 2550 KGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGI 2609

Query: 479  LGPKGEPGIPGDQGLQG---------------------PPGIPGIGGPSGPIGPPGIPGP 517
             G KG+ G  G +GL+G                     PPG PG+ G  G +G PG+PG 
Sbjct: 2610 RGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQ 2669

Query: 518  KGEPGL---------------PGPPGFPGI----GKPGVAGLHGP---------PGKPGA 549
             G PG                PGP G  G     G PG+ G  GP         PG PG+
Sbjct: 2670 SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGS 2729

Query: 550  LGPQGQPGLPGPPGPPGPPGPPAV----MPPTPPPQGE 583
            +GP+G  GL G  G  GPPG   V    +P  P  +GE
Sbjct: 2730 VGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGE 2767



 Score =  377 bits (969), Expect = e-104
 Identities = 264/639 (41%), Positives = 312/639 (48%), Gaps = 108/639 (16%)

Query: 38   PQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAP 97
            P +P +     P+ +P G Q P  P    G   G   P    G   P  PQ    ++  P
Sbjct: 2152 PGLPGERGMAGPEGKP-GLQGPRGPPGPVG-GHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209

Query: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQG 153
              G+   P +G   P  ++ G  GP G  G  GP G PGLPG     G PG  G+ G  G
Sbjct: 2210 --GETGPPGRGLTGPTGAV-GLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASG 2266

Query: 154  YPGV-GKPGMPGMPGKPG-----------------AMGMPGAKGE-----------IGQK 184
              G  G PG+PG PG PG                  +G+PGAKGE           +G+ 
Sbjct: 2267 KDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEP 2326

Query: 185  GEIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGPKGL-----PGPQGLRG 238
            G  G  G+PGP+G  G  G  G  G PG  G  G PGPKG +G  G+     PGP G  G
Sbjct: 2327 GAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPG 2386

Query: 239  PKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPG-------VGKPGVTGFPGPQGPLGKPG 290
             KGD G  G+PGAPGV G PG  GP G +G PG        G PG  G PGP GP G PG
Sbjct: 2387 VKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPG 2446

Query: 291  APGEPGPQG--------PIGVPGVQGPPGIPGI----GKPGQDGIPGQPGFPGGKGEQGL 338
            + G PG  G         +G+PG +G  G PGI    G+PGQ+G  G  G PG +GE+G 
Sbjct: 2447 SVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGE 2506

Query: 339  PGLPGPPGLPG--------IGKPGFPGPKGD---RGMGGVPGALGPRGE----------- 376
             G  G  GL G        +G PG  G KGD   RG  G+ G  GPRG+           
Sbjct: 2507 KGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKG 2566

Query: 377  ----KGPIGAPGIGG---PPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKG 429
                KG  G PG+ G   P G+PG  GIPG  G PG  G PG +GE G VG  GP G KG
Sbjct: 2567 EPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKG 2626

Query: 430  EPGLQG---FPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGE-- 484
            E G++G     G+ G  GE GPPG  GL G  G  GE G  G  G PG  GL+GPKG+  
Sbjct: 2627 ERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRG 2686

Query: 485  ----PGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAG 539
                PG  GDQG +G  G PGIGG  GP G  G  GP G PG  GP G  G+ G+ G  G
Sbjct: 2687 FDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERG 2746

Query: 540  -----LHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAV 573
                 + G PG PGA G +G+ G PGP GP G  G  A+
Sbjct: 2747 PPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAAL 2785



 Score =  310 bits (793), Expect = 4e-84
 Identities = 194/460 (42%), Positives = 225/460 (48%), Gaps = 70/460 (15%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV-G 158
            G   +P    E   A   GE G  GE G +G PGP G  G    G+ G PGP G PGV G
Sbjct: 2330 GDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKG 2389

Query: 159  KPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPG-IGKPGGPGLPG 217
              G+PG+PG PG +G PG  G  G+ G+ GP G  G  GPPG  G+PG +G PG PG  G
Sbjct: 2390 DLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVG 2449

Query: 218  QPGPKGDRGPKGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPGMHGPPGPVGLPG--- 270
             PG  G +G KG PG  GL GP+G++G     G  G PG +GP G+ GPPG  G  G   
Sbjct: 2450 PPGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKG 2508

Query: 271  -----------------VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIP 313
                             +G PG  G  G  G  G  G  G+ GP+G  G PG +G  G P
Sbjct: 2509 DVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEP 2568

Query: 314  G----IGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI----GKPGFPGPKGDRGMG 365
            G     G PG  G+ G  G PG  G  G PG PG  G+PGI    G  GF GP+G +G  
Sbjct: 2569 GDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGER 2628

Query: 366  GVPGALGPRGEKG------PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV 419
            GV GA G  GEKG      P G PG+ G  GE G PG+PG  G PG  G  GPKG+ G  
Sbjct: 2629 GVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFD 2688

Query: 420  GPQGPPGPKGE------PGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGV---- 469
            G  GP G +GE      PG+ GFPG  G  G  GPPG  G  GP GP+G  GQKG     
Sbjct: 2689 GQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPP 2748

Query: 470  -------------------PGLPGVPGLLGPKGEPGIPGD 490
                                G PG  G  G KGE  +  D
Sbjct: 2749 GERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score =  177 bits (449), Expect = 3e-44
 Identities = 113/268 (42%), Positives = 138/268 (51%), Gaps = 41/268 (15%)

Query: 95   PAPRMGKEAVPKKGKEIPLASLRGEQGPRGE---PGPRGPPGPPGLPGH-GIPGIKGKPG 150
            P PR  K  + ++G       L G++GPRG+   PG +G  G PG  G  G+PG++G  G
Sbjct: 2529 PGPRGAKGDMGERGPR----GLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLG 2584

Query: 151  PQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIG------------------------QKG 185
            PQG PG  G PG PG PGK G  G+ G KG++G                         KG
Sbjct: 2585 PQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKG 2644

Query: 186  EIGPMGIPGPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG 244
            E GP G PG  G  G  G PG+ G+ G PG  G  GPKGDRG  G PGP+G +G KG++G
Sbjct: 2645 EAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERG 2704

Query: 245  F-GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGP-----LGKPGAPGEPGP 297
              G+ G PG  G  G  GPPGP G  G  G  G+ G  G +GP     +G PG PG PG 
Sbjct: 2705 TPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGE 2764

Query: 298  QGPIGVPGVQGPPGIPGIGKPGQDGIPG 325
            +G  G PG  GP G  G     +D I G
Sbjct: 2765 RGEQGRPGPAGPRGEKGEAALTEDDIRG 2792



 Score =  137 bits (345), Expect = 4e-32
 Identities = 89/231 (38%), Positives = 107/231 (46%), Gaps = 51/231 (22%)

Query: 100  GKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPG-- 156
            G +  P       L  LRG  GP+G+PG  G PG PG PG  G+PGI+G+ G  G+ G  
Sbjct: 2563 GSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPR 2622

Query: 157  -----------------------VGKPGMPGM---------PGKPGAMGMPGAKGEIGQK 184
                                    G PG PG+         PG PG  G PG +G IG K
Sbjct: 2623 GLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPK 2682

Query: 185  GEIGPMGIPGP---QGPPGPHGLPGIGKPGGP-------GLPGQPGPKGDRGPKGLPGPQ 234
            G+ G  G PGP   QG  G  G PGIG   GP       G PG PG  G RGP+GL G +
Sbjct: 2683 GDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQK 2742

Query: 235  GLRGPKGDKGFGMPGAPGV------KGPPGMHGPPGPVGLPGVGKPGVTGF 279
            G RGP G++  G PG PG       +G PG  GP G  G   + +  + GF
Sbjct: 2743 GERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGF 2793


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  417 bits (1072), Expect = e-116
 Identities = 265/646 (41%), Positives = 303/646 (46%), Gaps = 190/646 (29%)

Query: 117  RGEQGPRGEPG------------PRGPPGPPGLPG-HGIPGIKGKPGPQGYPGV---GKP 160
            RG QGP+GEPG            PRGPPGP G  G  G PG+KG  GP G PG    G P
Sbjct: 787  RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPP 846

Query: 161  GMPGMPGKPGAMGMPGAKGEIGQKGEIG------------------------------PM 190
            G  G  G+ G  G PG KG  G+KGE G                              P 
Sbjct: 847  GRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQ 906

Query: 191  GIPGPQGPPGPHGLPGI-GKPGGPGLPGQPG----------------------------- 220
            G PG  GPPGP G+PG+ G PG  GLPGQPG                             
Sbjct: 907  GPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAH 966

Query: 221  -----PKGDRGPKGLPGPQGL------------------RGP--KGDKGF----GMPGAP 251
                  KG++G +G+PG  GL                  RG   +GD G     G+PG P
Sbjct: 967  PGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPP 1026

Query: 252  GV------KGPPGMHG---PPGPVGLPG----VGKPGVTGFPGPQGPLGKPGAPGEPGPQ 298
            G+      +GPPGM G   PPGP+G PG    VG PG+ G  G +G  G  G  GEPGP 
Sbjct: 1027 GLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPP 1086

Query: 299  GPIGVPGVQGPPGIPGI----------------GKPGQDGIPGQPGFPGGKGE------- 335
            G  G PG  GPPG+PGI                G PG +G+PG PG  G +GE       
Sbjct: 1087 GQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNS 1146

Query: 336  --------QGLPGLPGPPGLPG----IGKPGFPGPKGDRGMGGV---------PGALGPR 374
                    QG PG PGPPG PG    +G PG PGP+ ++G  G+         PG  GP 
Sbjct: 1147 GEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPP 1206

Query: 375  GEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIG------------FPGPKGEGGIVGPQ 422
            G +GP G  G+ G  G+PGL G PGP GPPG +G             PGPKG+ G  GP 
Sbjct: 1207 GIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPP 1266

Query: 423  GP---PGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIG-----------PKGEAGQKG 468
            G    PG +GEPG  G  G+PG  G VGPPG  G PGP G             GE G  G
Sbjct: 1267 GSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAG 1326

Query: 469  VPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG 528
            +PG PG PG  GP GEPG  G  G +GPPG  G  GP GP G PG  G KG+ G  G  G
Sbjct: 1327 LPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAG 1386

Query: 529  FPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVM 574
             PG   PG +G  GP G PG  G +G PG PGP G PG PG P  M
Sbjct: 1387 MPG--GPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM 1430



 Score =  416 bits (1069), Expect = e-116
 Identities = 261/634 (41%), Positives = 305/634 (48%), Gaps = 129/634 (20%)

Query: 107  KGKEIPLASLRGEQGPRGEPGPRG-----PPGPPGLPG----HGIPGIKGKPGPQGYPGV 157
            +G    +A   G+ GP+GE GP G      PG PGLPG     G+ G++G+PGP G    
Sbjct: 731  QGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQ 790

Query: 158  GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPG 217
            G  G PG PG PG  G+PG +G  G  GE G  G PG +G  GP G PG    G PG  G
Sbjct: 791  GPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDG 850

Query: 218  QPGPKGDRGPKGLPGPQGLRGPKGDKG---------FGMPGAPGV----------KGPPG 258
            Q G  G RG  G  GP+G +G  G+            GMPGAPG+          +GPPG
Sbjct: 851  QQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPG 910

Query: 259  MHGPPGPVGLPGV-GKPGVTGFPGPQG---PLGK----------------PGAPGEPGPQ 298
            + GPPGP G+PG+ G PG  G PG  G    LG                  G    PG  
Sbjct: 911  IPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYL 970

Query: 299  GPIGVPGVQGPPGIPGI---------------------------GKPGQDGIPGQPGFPG 331
               G  G QG PG+PG+                           G  G  G+PG PG PG
Sbjct: 971  VEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPG 1030

Query: 332  GKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGM------GGVPGALGPRGEKGPIGAPG 384
             +GE+G PG+ G PG PG IG PGFPG  G  G+       G+ G  G +GE GP G PG
Sbjct: 1031 QRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPG 1090

Query: 385  IGGPPGEPGLPGIPGPM------------GPPGAIGFPGPKGEGGIVGPQGPPGPKGEPG 432
              G  G PGLPGI G              GPPG+ G PGP G  G  G +GP G  GE G
Sbjct: 1091 YPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKG 1150

Query: 433  LQGFPGKPGFLGEVGPPGMR---GLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPG 489
             QGF G+PGF G  GPPG     G PGP GP+ E G +G+ G  G+PG  GP G PGI G
Sbjct: 1151 DQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQG 1210

Query: 490  DQGL------QGPPGIPGIGGPSGP---IGPPGIPGPKGEPGLPGPPGFPG-IGKPGVAG 539
              GL       G PG+ G  GP+GP   +GPPG  G  G PGLPGP G  G  G PG  G
Sbjct: 1211 PAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTG 1270

Query: 540  LHGPPGKPGALGPQGQPGLP---GPPGPPGPPGPPAV-------------------MPPT 577
              G  G+PGA+GPQG+PG P   GPPGPPG PGP  +                   +P  
Sbjct: 1271 RPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQ 1330

Query: 578  PPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP 611
            P P G   P    G DG         K+G  G P
Sbjct: 1331 PGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPP 1364



 Score =  408 bits (1048), Expect = e-113
 Identities = 258/572 (45%), Positives = 284/572 (49%), Gaps = 90/572 (15%)

Query: 118  GEQGPRGEPGPRGPPGPPGLPGH-GIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMP 175
            G+ G  G PG  GPPG PG  G  G PG++G PGP G  G  G PG  G PG PG  G  
Sbjct: 1012 GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071

Query: 176  GAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI-------------GKPGGPGLPGQPGPK 222
            G  G  G KGE GP G PG  G  GP GLPGI             G+PG PG  G PGP 
Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPP 1131

Query: 223  GDRGPKGLPGPQGLRGPKGDKGF-GMPGAPGVKGPPGMHGPPGPVGLPGV-GKPGVTGFP 280
            G  GP+G  GPQG  G KGD+GF G PG PG  GPPG  G  G  G PG   + G  G  
Sbjct: 1132 GPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIR 1191

Query: 281  GPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLP 339
            GP G  G PG PG PG QGP G+ G+ G  G PG+ G PG  G PG  G PG KG+ G P
Sbjct: 1192 GPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHP 1251

Query: 340  GLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP- 398
            GLPGP G    GKPG PG  G  G  G PGA+GP+G  GP G  G  GPPG+PG  GI  
Sbjct: 1252 GLPGPKG--DCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISA 1309

Query: 399  -GPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGK---PGFLGEVGPPGMRGL 454
             G  G  GA G  G  G  G  GP G PGP GEPG  G  GK   PG  G  GPPG +G 
Sbjct: 1310 VGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGD 1369

Query: 455  PGPIGPKGEAGQKGVPGLPGVPGLL---------GPKGEPGIPGDQGLQGPPGIPGIGGP 505
            PG  G KG+AG+KG  G+PG PG           GP GE G PG  G  G PG+PG+ G 
Sbjct: 1370 PGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGS 1429

Query: 506  SGPI------------------------------------------GPPGIPGPKGEPGL 523
             G +                                          GPPG  G  G PG 
Sbjct: 1430 MGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGA 1489

Query: 524  PGPPGFPG-------IGKPGVAGLHGPPGKPG--ALGPQGQPGLPGPPGPPGPPGPPAVM 574
            PG PG PG        G PGV GL G  G+ G   +G  G+ GLPGPPGP GPPG    M
Sbjct: 1490 PGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPG-YGKM 1548

Query: 575  PPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKG 606
              T P   + +P    GI G   P     K G
Sbjct: 1549 GATGPMGQQGIP----GIPGPPGPMGQPGKAG 1576



 Score =  397 bits (1020), Expect = e-110
 Identities = 252/581 (43%), Positives = 287/581 (49%), Gaps = 120/581 (20%)

Query: 113  LASLRGEQGP---RGEPGPRGPPGPPGLPGH----GIPGIKGKPGPQGYPG-VGKPGMPG 164
            L   RGE+GP   RG PGP GP GPPG PG     G+PG++G+ G  G  G  G+PG PG
Sbjct: 1028 LPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPG 1087

Query: 165  MPGKPGAMG---MPGAKGE------IGQKGEIGPMG---IPGPQGPPGPHGLPGI----- 207
             PG PGA G   +PG KGE       G+KGE GP G   +PGP GP GP G  G      
Sbjct: 1088 QPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSG 1147

Query: 208  -----GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF----GMPGAPGVKGPPG 258
                 G  G PG PG PGP G  G  G PGP G +  KG +G     G+PG+PG  GPPG
Sbjct: 1148 EKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPG 1207

Query: 259  MHGPPGPVGLPGV-GKPGVTGFPGPQGP---------LGKPGAPGEPGPQGPIGVPGVQG 308
            + GP G  GL G  GKPG+ G PGP GP          GK G PG PGP+G  G PG  G
Sbjct: 1208 IQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPG 1267

Query: 309  PPGIPGI-GKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367
              G PG  G+PG  G  G+PG PG  G  G PG PGP G+  +G  G  G  G+RG+ G+
Sbjct: 1268 STGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGL 1327

Query: 368  PGALGPRGEKGPIGAPGIGG------PPGEPGLPGIPGPMGPPGAIG------------F 409
            PG  GP G  GP G PG  G      PPG+ G  G PGP G PGA G             
Sbjct: 1328 PGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGM 1387

Query: 410  PGPKGEGGIVGPQGPPGPKGE------PGLQGFPGKPGFLGEVG---------------- 447
            PG  G+ G +GP GPPGP GE      PG  G PG PG  G +G                
Sbjct: 1388 PGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEI 1447

Query: 448  -----------------PPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGD 490
                             P  M   PG  GP G+ G  G PG PG PGL    G+ G  G 
Sbjct: 1448 IKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGL---PGQIGREGR 1504

Query: 491  QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGAL 550
            QGL G  G+PG  G  G IG  GI G  G PG PGP G PG GK G           G +
Sbjct: 1505 QGLPGVRGLPGTKGEKGDIG-IGIAGENGLPGPPGPQGPPGYGKMGAT---------GPM 1554

Query: 551  GPQGQPGLPGPPGPPGPPGPPAVMPPTP-----PPQGEYLP 586
            G QG PG+PGPPGP G PG      P+      P + +Y P
Sbjct: 1555 GQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPP 1595



 Score =  362 bits (928), Expect = e-100
 Identities = 263/729 (36%), Positives = 311/729 (42%), Gaps = 220/729 (30%)

Query: 112  PLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPG 170
            P A L+  +GP+GE G  G  GP GLPG    G KG+ G +G  G+ G PG PG  G+PG
Sbjct: 366  PDAPLQCAEGPKGEKGESGALGPSGLPGS--TGEKGQKGEKGDGGIKGVPGKPGRDGRPG 423

Query: 171  AMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP-GQPGPKGDRGPKG 229
             + + G KG+ G  G +GP G+ G  GPPG  G PGIG PG PG P G PGPKGD+G  G
Sbjct: 424  EICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSG 483

Query: 230  LPGPQ---------GLRGPKGD---------KGF----GMPGAPGVKGPPG--------- 258
            +PG +         G++G KGD         +GF    G+PG PG KG PG         
Sbjct: 484  IPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDP 543

Query: 259  ---------------------------MHGPPGPVGLPGVGKP------GVTGFPGPQGP 285
                                         G  G VG PG G P      GV G  G +G 
Sbjct: 544  GIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGN 603

Query: 286  LGKPGAPGEPGPQGPIGVPGV---------------------------------QGPPGI 312
             G+ G  G PGP GP+G  G+                                 +G PG 
Sbjct: 604  FGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGP 663

Query: 313  PGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGL---PGI-GKPGFPGPKGDRG----- 363
            PG G PG+ G  G+ G  G KG+ G PG PG PG    PG+ G+PG  GP G +G     
Sbjct: 664  PGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDG 723

Query: 364  -------------MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP 410
                         M G PG  GP+GE+GP G  G  G PG+PGLPG+ GP G  G  G P
Sbjct: 724  CTACPSLQGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPGLPGVQGPPGLKGVQGEP 782

Query: 411  GPKGEG-----------------GIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRG 453
            GP G G                 G+ GP+GPPGP GE G QG PG  G  G VGPPG   
Sbjct: 783  GPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPG-AS 841

Query: 454  LPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPG-----IPGDQGLQGPPGIPGIGGPS-- 506
            + GP G  G+ GQ G+ G PG  G  G KGEPG       GD    G PG PG+   S  
Sbjct: 842  VSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSW 901

Query: 507  --GPIGPPGIPGPKGEPGLPGPPGFPG----IGKPG----------------------VA 538
              GP GPPGIPGP G PG+PG  G PG     G+PG                      V 
Sbjct: 902  QPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQ 961

Query: 539  GLHGPPG---KPGALGPQGQPGLP--------------------------------GPPG 563
            G    PG   + G  G QG PG+P                                G PG
Sbjct: 962  GQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPG 1021

Query: 564  PPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYE----MPAFT 619
             PGPPG P       PP     P    G  G   P  +    G  G P  +    +   T
Sbjct: 1022 LPGPPGLPGQRGEEGPPGMRGSP----GPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLT 1077

Query: 620  AELTAPFPP 628
             +   P PP
Sbjct: 1078 GDKGEPGPP 1086



 Score =  298 bits (764), Expect = 9e-81
 Identities = 211/518 (40%), Positives = 240/518 (46%), Gaps = 110/518 (21%)

Query: 182 GQKGEIGPMGIPGPQGPPGPHGLPGIG-------KPGGP-----GLPGQPGPKGDRGPKG 229
           G KG  G  G+PGP   PG  G  G          P  P     G  G+ G  G  GP G
Sbjct: 334 GPKGGKGERGLPGP---PGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSG 390

Query: 230 LPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGK 288
           LPG  G +G KG+KG G  G  GV G PG  G PG + + G  G+ G  GF GP+G  G+
Sbjct: 391 LPGSTGEKGQKGEKGDG--GIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGE 448

Query: 289 PGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLP 348
           PG PG PGP G IG+PG  G PG    G PG  G  G  G PG +G  G PG PG  G  
Sbjct: 449 PGPPGLPGPPG-IGLPGTPGDPG----GPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEK 503

Query: 349 G----------------IGKPGFPGPKGDRG----MGGVPGALGPRGEKGP--------- 379
           G                +G PG PGPKG+ G      G PG  G +GEKG          
Sbjct: 504 GDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVV 563

Query: 380 -----IGAPGIGGPPGEP--GLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPG 432
                + + G  G  G P  GLPG+PG  G PG  G  G  GE G  G  GPPGP G  G
Sbjct: 564 GAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAG 623

Query: 433 LQG------------------------FPGKPGFLGEVGPPGMRGLPGPIGPKGE---AG 465
           ++G                         PG  G  GE GPPG  GLPG  G  GE    G
Sbjct: 624 IKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKG 682

Query: 466 QKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG------PS--GPI----GPPG 513
           QKG  G PG PG  G  G PG+ G+ G+QGP G  G  G      PS  G +    G PG
Sbjct: 683 QKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPG 742

Query: 514 IPGPKGE--------PGLPGPPGFPGI-GKPGVAGLHGPPGKP--GALGPQGQPGLPGPP 562
            PGPKGE        PG PG PG PG+ G PG+ G+ G PG P  G  GPQG+PG PG P
Sbjct: 743 QPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLP 802

Query: 563 GPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHA 600
           G  G PGP     PT     +  P +      V PP A
Sbjct: 803 GIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGA 840



 Score =  223 bits (567), Expect = 7e-58
 Identities = 152/401 (37%), Positives = 168/401 (41%), Gaps = 117/401 (29%)

Query: 114  ASLRGEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQGYPG----VGKPGMPGMPGK 168
            A L G  G  G+PG RG PGP G PG  G PG KGK G  G PG     GKPG PG  G+
Sbjct: 1212 AGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGR 1271

Query: 169  PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIG-------------------- 208
            PGA G PGA G  G+ G  G +G PGP G PGP G+  +G                    
Sbjct: 1272 PGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQP 1331

Query: 209  -KPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKG----------------FGMPGAP 251
              PG PG PG+PG  G  G +G PG QG  GP G KG                 GMPG P
Sbjct: 1332 GPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGP 1391

Query: 252  GVKGPPGMHGPPGPVGLPG-------VGKPGVTGFPGPQG-------------------- 284
            G  G  G  GPPGP G  G        G PG+ G PG  G                    
Sbjct: 1392 GKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMF 1451

Query: 285  -------------PLGKPGAPGEPGPQGPIGVPGVQGPPGIPG----IGKPGQDGIPGQP 327
                         P+    APG PGP G  G PG  G PG PG    IG+ G+ G+PG  
Sbjct: 1452 DERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVR 1511

Query: 328  GFPGGKGEQG-----------LPGLPGPPGLPGIGK------------PGFPGPKGDRGM 364
            G PG KGE+G           LPG PGP G PG GK            PG PGP G  G 
Sbjct: 1512 GLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQ 1571

Query: 365  GGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPG 405
             G  G   P        +   G  P E   P +    GP G
Sbjct: 1572 PGKAGHCNP--------SDCFGAMPMEQQYPPMKTMKGPFG 1604



 Score =  189 bits (481), Expect = 6e-48
 Identities = 138/366 (37%), Positives = 162/366 (44%), Gaps = 71/366 (19%)

Query: 309 PPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIG-------KPGFP----- 356
           PP + G         P  P   GGKGE+GLPG PG  G  G          P  P     
Sbjct: 317 PPCVHGARDSNVTLAPSGP--KGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAE 374

Query: 357 GPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEG 416
           GPKG++G  G  G  G  G  G  G  G  G  G  G+PG PG  G PG I   GPKG+ 
Sbjct: 375 GPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQK 434

Query: 417 GIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP-GPIGPKGEAGQKGVP----- 470
           G  G  GP G  GEPG  G PG PG    +G PG  G P GP GPKG+ G  G+P     
Sbjct: 435 GDPGFVGPEGLAGEPGPPGLPGPPG----IGLPGTPGDPGGPPGPKGDKGSSGIPGKEGP 490

Query: 471 -GLPGVPGLLGPKGEP---------------GIPGDQGLQGPPG--IPGIGGPSGPIGPP 512
            G PG PG+ G KG+P               G+PG  G +G PG  +P  G P    G  
Sbjct: 491 GGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDP----GIQ 546

Query: 513 GIPGPKGEP-----------------GLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQ 555
           GI G KGEP                 G  G  G PG G PG+ G  G PG  G  G  G+
Sbjct: 547 GIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGE 606

Query: 556 PGLPGPPGPPGPPGPPAVM-----PPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGG 610
            G  G PGPPGP GP  +      P  P P    L D  + +  +  P     +KG+ G 
Sbjct: 607 AGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGP---SGEKGEPGP 663

Query: 611 PAYEMP 616
           P + +P
Sbjct: 664 PGFGLP 669



 Score =  107 bits (268), Expect = 3e-23
 Identities = 80/215 (37%), Positives = 91/215 (42%), Gaps = 50/215 (23%)

Query: 444 GEVGPPGMRGLPGPIGPKGEAGQKGV---------PGLP--------------------G 474
           G  G  G RGLPGP G K   G+KG          P  P                    G
Sbjct: 334 GPKGGKGERGLPGPPGSK---GEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSG 390

Query: 475 VPGLLGPKGEPGIPGDQGLQGPPGIPG---------IGGPSGPIGPPGIPGPK---GEPG 522
           +PG  G KG+ G  GD G++G PG PG         + GP G  G PG  GP+   GEPG
Sbjct: 391 LPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPG 450

Query: 523 LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQG 582
            PG PG PGIG PG  G   P G PG  G +G  G+PG  GP G PG P V      P  
Sbjct: 451 PPGLPGPPGIGLPGTPG--DPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDP-C 507

Query: 583 EYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPA 617
           E  P +  G            K G  G P   +PA
Sbjct: 508 EVCPTLPEGFQNFV---GLPGKPGPKGEPGDPVPA 539



 Score =  107 bits (267), Expect = 4e-23
 Identities = 74/206 (35%), Positives = 84/206 (40%), Gaps = 49/206 (23%)

Query: 98   RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG---------- 147
            R G    P K   +      G  G RG PG  GP G PGLP  G+PG  G          
Sbjct: 1384 RAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLP--GVPGSMGDMVNYDEIKR 1441

Query: 148  --------------------------KPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEI 181
                                           G P  G PG  G PG+PGA G PG  G+I
Sbjct: 1442 FIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRP--GPPGKDGAPGRPGAPGSPGLPGQI 1499

Query: 182  GQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKG 241
            G++G  G  G+ G  G  G  G  GIG  G  GLPG PGP+G  G     G  G  GP G
Sbjct: 1500 GREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPG----YGKMGATGPMG 1555

Query: 242  DKGFGMPGAPGVKGPPGMHGPPGPVG 267
             +G      PG+ GPPG  G PG  G
Sbjct: 1556 QQGI-----PGIPGPPGPMGQPGKAG 1576


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.150    0.494 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,881,263
Number of Sequences: 37866
Number of extensions: 5831130
Number of successful extensions: 264119
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 762
Number of HSP's successfully gapped in prelim test: 1682
Number of HSP's that attempted gapping in prelim test: 21981
Number of HSP's gapped (non-prelim): 28127
length of query: 744
length of database: 18,247,518
effective HSP length: 110
effective length of query: 634
effective length of database: 14,082,258
effective search space: 8928151572
effective search space used: 8928151572
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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