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Search of human proteins with 170016091
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
(2765 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 5692 0.0
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 3892 0.0
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 3536 0.0
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 3301 0.0
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 3295 0.0
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 3286 0.0
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 235 5e-61
gi|153946395 tenascin C precursor [Homo sapiens] 233 2e-60
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 156 2e-37
gi|134244285 Notch homolog 3 [Homo sapiens] 152 6e-36
gi|148833508 notch1 preproprotein [Homo sapiens] 151 8e-36
gi|24041035 notch 2 preproprotein [Homo sapiens] 149 5e-35
gi|4557679 jagged 1 precursor [Homo sapiens] 142 6e-33
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 139 4e-32
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 136 3e-31
gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ... 135 6e-31
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 134 2e-30
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 134 2e-30
gi|157384973 tenascin R [Homo sapiens] 132 6e-30
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 130 1e-29
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 129 4e-29
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 129 4e-29
gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens] 129 4e-29
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 129 5e-29
gi|55770876 notch4 preproprotein [Homo sapiens] 127 2e-28
gi|122937283 6720455I24Rik homolog [Homo sapiens] 126 3e-28
gi|112420992 crumbs homolog 2 [Homo sapiens] 124 1e-27
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 123 3e-27
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 119 3e-26
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 119 3e-26
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 5692 bits (14765), Expect = 0.0
Identities = 2765/2765 (100%), Positives = 2765/2765 (100%)
Query: 1 MDVKDRRHRSLTRGRCGKECRYTSSSLDSEDCRVPTQKSYSSSETLKAYDHDSRMHYGNR 60
MDVKDRRHRSLTRGRCGKECRYTSSSLDSEDCRVPTQKSYSSSETLKAYDHDSRMHYGNR
Sbjct: 1 MDVKDRRHRSLTRGRCGKECRYTSSSLDSEDCRVPTQKSYSSSETLKAYDHDSRMHYGNR 60
Query: 61 VTDLIHRESDEFPRQGTNFTLAELGICEPSPHRSGYCSDMGILHQGYSLSTGSDADSDTE 120
VTDLIHRESDEFPRQGTNFTLAELGICEPSPHRSGYCSDMGILHQGYSLSTGSDADSDTE
Sbjct: 61 VTDLIHRESDEFPRQGTNFTLAELGICEPSPHRSGYCSDMGILHQGYSLSTGSDADSDTE 120
Query: 121 GGMSPEHAIRLWGRGIKSRRSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPSLL 180
GGMSPEHAIRLWGRGIKSRRSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPSLL
Sbjct: 121 GGMSPEHAIRLWGRGIKSRRSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPSLL 180
Query: 181 PSAQLPSSHNPPPVSCQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSGPP 240
PSAQLPSSHNPPPVSCQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSGPP
Sbjct: 181 PSAQLPSSHNPPPVSCQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSGPP 240
Query: 241 NHHSQSTLRPPLPPPHNHTLSHHHSSANSLNRNSLTNRRSQIHAPAPAPNDLATTPESVQ 300
NHHSQSTLRPPLPPPHNHTLSHHHSSANSLNRNSLTNRRSQIHAPAPAPNDLATTPESVQ
Sbjct: 241 NHHSQSTLRPPLPPPHNHTLSHHHSSANSLNRNSLTNRRSQIHAPAPAPNDLATTPESVQ 300
Query: 301 LQDSWVLNSNVPLETRHFLFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRK 360
LQDSWVLNSNVPLETRHFLFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRK
Sbjct: 301 LQDSWVLNSNVPLETRHFLFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRK 360
Query: 361 AFKLKKPSKYCSWKCAALSAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFNNGIRT 420
AFKLKKPSKYCSWKCAALSAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFNNGIRT
Sbjct: 361 AFKLKKPSKYCSWKCAALSAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFNNGIRT 420
Query: 421 GLPGNDDVATMPSGGKVPWSLKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLK 480
GLPGNDDVATMPSGGKVPWSLKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLK
Sbjct: 421 GLPGNDDVATMPSGGKVPWSLKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLK 480
Query: 481 FNISLGKDALFGVYIRRGLPPSHAQYDFMERLDGKEKWSVVESPRERRSIQTLVQNEAVF 540
FNISLGKDALFGVYIRRGLPPSHAQYDFMERLDGKEKWSVVESPRERRSIQTLVQNEAVF
Sbjct: 481 FNISLGKDALFGVYIRRGLPPSHAQYDFMERLDGKEKWSVVESPRERRSIQTLVQNEAVF 540
Query: 541 VQYLDVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGA 600
VQYLDVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGA
Sbjct: 541 VQYLDVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGA 600
Query: 601 DCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSA 660
DCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSA
Sbjct: 601 DCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSA 660
Query: 661 GYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDT 720
GYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDT
Sbjct: 661 GYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDT 720
Query: 721 GLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTC 780
GLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTC
Sbjct: 721 GLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTC 780
Query: 781 KDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCA 840
KDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCA
Sbjct: 781 KDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCA 840
Query: 841 DNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQTDWPAVKSFYDRIKLL 900
DNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQTDWPAVKSFYDRIKLL
Sbjct: 841 DNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQTDWPAVKSFYDRIKLL 900
Query: 901 AGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITRQDGTFD 960
AGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITRQDGTFD
Sbjct: 901 AGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITRQDGTFD 960
Query: 961 LIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENSIPSCDLSGFVRPDP 1020
LIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENSIPSCDLSGFVRPDP
Sbjct: 961 LIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENSIPSCDLSGFVRPDP 1020
Query: 1021 IIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLLKITMTQ 1080
IIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLLKITMTQ
Sbjct: 1021 IIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLLKITMTQ 1080
Query: 1081 STVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVGFE 1140
STVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVGFE
Sbjct: 1081 STVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVGFE 1140
Query: 1141 YETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQFLTQQPA 1200
YETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQFLTQQPA
Sbjct: 1141 YETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQFLTQQPA 1200
Query: 1201 IITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIFPSRNVT 1260
IITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIFPSRNVT
Sbjct: 1201 IITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIFPSRNVT 1260
Query: 1261 SILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLAGNSEVV 1320
SILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLAGNSEVV
Sbjct: 1261 SILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLAGNSEVV 1320
Query: 1321 AGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQNGIISTL 1380
AGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQNGIISTL
Sbjct: 1321 AGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQNGIISTL 1380
Query: 1381 LGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITENHQVSII 1440
LGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITENHQVSII
Sbjct: 1381 LGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITENHQVSII 1440
Query: 1441 AGRPMHCQVPGIDYSLSKLAIHSALESASAIAISHTGVLYITETDEKKINRLRQVTTNGE 1500
AGRPMHCQVPGIDYSLSKLAIHSALESASAIAISHTGVLYITETDEKKINRLRQVTTNGE
Sbjct: 1441 AGRPMHCQVPGIDYSLSKLAIHSALESASAIAISHTGVLYITETDEKKINRLRQVTTNGE 1500
Query: 1501 ICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADLGNIRIRA 1560
ICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADLGNIRIRA
Sbjct: 1501 ICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADLGNIRIRA 1560
Query: 1561 VSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSTDNDVTELI 1620
VSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSTDNDVTELI
Sbjct: 1561 VSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSTDNDVTELI 1620
Query: 1621 DNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTYDGNTGLL 1680
DNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTYDGNTGLL
Sbjct: 1621 DNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTYDGNTGLL 1680
Query: 1681 ATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDDDVTVITN 1740
ATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDDDVTVITN
Sbjct: 1681 ATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDDDVTVITN 1740
Query: 1741 LSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLAGTITPTIGRCNIS 1800
LSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLAGTITPTIGRCNIS
Sbjct: 1741 LSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLAGTITPTIGRCNIS 1800
Query: 1801 LPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYDDHRKFTL 1860
LPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYDDHRKFTL
Sbjct: 1801 LPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYDDHRKFTL 1860
Query: 1861 RIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIVSRMFADG 1920
RIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIVSRMFADG
Sbjct: 1861 RIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIVSRMFADG 1920
Query: 1921 KVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVARHSMSTHTSIGYIRNIYNP 1980
KVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVARHSMSTHTSIGYIRNIYNP
Sbjct: 1921 KVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVARHSMSTHTSIGYIRNIYNP 1980
Query: 1981 PESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGYDETTGVL 2040
PESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGYDETTGVL
Sbjct: 1981 PESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGYDETTGVL 2040
Query: 2041 KMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDYTYHDNSFRIASIKPVISE 2100
KMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDYTYHDNSFRIASIKPVISE
Sbjct: 2041 KMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDYTYHDNSFRIASIKPVISE 2100
Query: 2101 TPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDTHGRIKEVQYEMFR 2160
TPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDTHGRIKEVQYEMFR
Sbjct: 2101 TPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDTHGRIKEVQYEMFR 2160
Query: 2161 SLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTWRYSYDLN 2220
SLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTWRYSYDLN
Sbjct: 2161 SLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTWRYSYDLN 2220
Query: 2221 GNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLCQRGSDIFEYNSKGLLTRA 2280
GNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLCQRGSDIFEYNSKGLLTRA
Sbjct: 2221 GNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLCQRGSDIFEYNSKGLLTRA 2280
Query: 2281 YNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSEITSLYYD 2340
YNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSEITSLYYD
Sbjct: 2281 YNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSEITSLYYD 2340
Query: 2341 LQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSNPDFQMVI 2400
LQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSNPDFQMVI
Sbjct: 2341 LQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSNPDFQMVI 2400
Query: 2401 GFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKEPAPFNLYMFKSNNPLSSE 2460
GFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKEPAPFNLYMFKSNNPLSSE
Sbjct: 2401 GFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKEPAPFNLYMFKSNNPLSSE 2460
Query: 2461 LDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYELSESQASENGQLITGVQQT 2520
LDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYELSESQASENGQLITGVQQT
Sbjct: 2461 LDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYELSESQASENGQLITGVQQT 2520
Query: 2521 TERHNQAFMALEGQVITKKLHASIREKAGHWFATTTPIIGKGIMFAIKEGRVTTGVSSIA 2580
TERHNQAFMALEGQVITKKLHASIREKAGHWFATTTPIIGKGIMFAIKEGRVTTGVSSIA
Sbjct: 2521 TERHNQAFMALEGQVITKKLHASIREKAGHWFATTTPIIGKGIMFAIKEGRVTTGVSSIA 2580
Query: 2581 SEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGTTIGRKVLESGVNV 2640
SEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGTTIGRKVLESGVNV
Sbjct: 2581 SEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGTTIGRKVLESGVNV 2640
Query: 2641 TVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVLDQARQRALGTAWA 2700
TVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVLDQARQRALGTAWA
Sbjct: 2641 TVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVLDQARQRALGTAWA 2700
Query: 2701 KEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPELADSSSNIQFLRQN 2760
KEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPELADSSSNIQFLRQN
Sbjct: 2701 KEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPELADSSSNIQFLRQN 2760
Query: 2761 EMGKR 2765
EMGKR
Sbjct: 2761 EMGKR 2765
>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
Length = 2699
Score = 3892 bits (10092), Expect = 0.0
Identities = 1863/2782 (66%), Positives = 2247/2782 (80%), Gaps = 100/2782 (3%)
Query: 1 MDVKDRR-HRSLTRGRCGKECRYTSSSLDSEDCRVPTQKSYSSSETLKAYDHDS-RMHYG 58
MDVK+RR + SLT+ R KE RYT+SS D+E+CRVPTQKSYSSSETLKA+DHDS R+ YG
Sbjct: 1 MDVKERRPYCSLTKSRREKERRYTNSSADNEECRVPTQKSYSSSETLKAFDHDSSRLLYG 60
Query: 59 NRVTDLIHRESDEFPRQGTNFTLAELGICEPSPHRSGYCSDMGILHQGYSLSTGSDADSD 118
NRV DL+HRE+DEF RQG NFTL +LG+CEP+ R
Sbjct: 61 NRVKDLVHREADEFTRQGQNFTLRQLGVCEPATRR------------------------- 95
Query: 119 TEGGMSPEHAIRLWGRGIKSRRSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPS 178
G+ GL R S +D+D EN++ +
Sbjct: 96 ----------------GLAFCAEMGLPHRGYSISAGSDADTENEA-------VMSPEHAM 132
Query: 179 LLPSAQLPSSHNPPPVSCQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSG 238
L + S + SC L S ++ + T+ + E +S +
Sbjct: 133 RLWGRGVKSGRS----SC----LSSRSNSALTLTDTEHENKSDS------------ENEQ 172
Query: 239 PPNHHSQSTLRPPLPPPHNHTLSHHHSSANSLNRNSLTNRRSQIHAPAPA-PNDLATTPE 297
P ++ QSTL+P LPP H + HH S SLNRNSLTNRR+Q AP A P +L TTPE
Sbjct: 173 PASNQGQSTLQP-LPPSHKQHSAQHHPSITSLNRNSLTNRRNQSPAPPAALPAELQTTPE 231
Query: 298 SVQLQDSWVLNSNVPLETRHFLFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTF 357
SVQLQDSWVL SNVPLE+RHFLFKT +G+TPLFS+++PGY + SG+VY+PP R LPRNT
Sbjct: 232 SVQLQDSWVLGSNVPLESRHFLFKTGTGTTPLFSTATPGYTMASGSVYSPPTRPLPRNTL 291
Query: 358 SRKAFKLKKPSKYCSWKCAALSAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFNNG 417
SR AFK KK SKYCSWKC AL A+ ++LLAILL+YFIAMHL GLNWQLQ + TF NG
Sbjct: 292 SRSAFKFKKSSKYCSWKCTALCAVGVSVLLAILLSYFIAMHLFGLNWQLQQTENDTFENG 351
Query: 418 IRTGLPGNDDVATMPSG--GKVP-WSLKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHIS 474
+ ++PSG GK+ ++ +N++IDSGE ++GRR QE+PPG+FWRSQ+ I
Sbjct: 352 KVNSDTMPTNTVSLPSGDNGKLGGFTQENNTIDSGELDIGRRAIQEIPPGIFWRSQLFID 411
Query: 475 QPQFLKFNISLGKDALFGVYIRRGLPPSHAQYDFMERLDG-----KEKWSVVESPRERRS 529
QPQFLKFNISL KDAL GVY R+GLPPSH QYDF+E LDG +E+ S++E+ R R
Sbjct: 412 QPQFLKFNISLQKDALIGVYGRKGLPPSHTQYDFVELLDGSRLIAREQRSLLETERAGRQ 471
Query: 530 IQTLVQNEAVFVQYLDVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSG 589
+++ +EA F+QYLD G+WHLAFYNDGK+ E VSFNT+V++SV +CPRNCHGNGECVSG
Sbjct: 472 ARSVSLHEAGFIQYLDSGIWHLAFYNDGKNAEQVSFNTIVIESVVECPRNCHGNGECVSG 531
Query: 590 VCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHG 649
CHCFPGFLG DC++AACPVLCSGNGQYSKG C C+SGWKG ECDVP QCIDP CGG G
Sbjct: 532 TCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRG 591
Query: 650 SCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQ 709
CI G+C C++GYKGE CEE DC+DP CS+HGVC++GEC CSPGWGG NCE+ + CPDQ
Sbjct: 592 ICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWGGSNCEILKTMCPDQ 651
Query: 710 CSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRV 769
CSGHGTYL ++G C+CDPNW GPDCS E+CSVDCG+HGVC+GG CRCEEGWTG AC+QR
Sbjct: 652 CSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTCRCEEGWTGPACNQRA 711
Query: 770 CHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGP 829
CHPRC EHGTCKDGKCEC +GWNGEHCTI+GCP LCN NGRCTL QN W CVCQ GWRG
Sbjct: 712 CHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLDQNGWHCVCQPGWRGA 771
Query: 830 GCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQG--QTDW 887
GC+VAMET C D+KDNEGDGL+DC+DPDCCLQS+CQN CRG DP DII Q
Sbjct: 772 GCDVAMETLCTDSKDNEGDGLIDCMDPDCCLQSSCQNQPYCRGLPDPQDIISQSLQSPSQ 831
Query: 888 PAVKSFYDRIKLLAGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPK 947
A KSFYDRI L G DSTH+IPGE+PFN SL S+IRGQV+T DGTPL+GVNVSF YP+
Sbjct: 832 QAAKSFYDRISFLIGSDSTHVIPGESPFNKSLASVIRGQVLTADGTPLIGVNVSFFHYPE 891
Query: 948 YGYTITRQDGTFDLIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENSI 1007
YGYTITRQDG FDL+ANGGASLTL FER+PF++Q TVW+PWN FY MDTLVMK EEN I
Sbjct: 892 YGYTITRQDGMFDLVANGGASLTLVFERSPFLTQYHTVWIPWNVFYVMDTLVMKKEENDI 951
Query: 1008 PSCDLSGFVRPDPIIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRT 1067
PSCDLSGFVRP+PII+SSPLSTFF ++P +PI+PETQVLHEE +PG+++KL YLSSR
Sbjct: 952 PSCDLSGFVRPNPIIVSSPLSTFFRSSPEDSPIIPETQVLHEETTIPGTDLKLSYLSSRA 1011
Query: 1068 AGYKSLLKITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRV 1127
AGYKS+LKITMTQS +P NL++VHLMVAV G LFQK F ASPNLAYTFIWDKTDAY Q+V
Sbjct: 1012 AGYKSVLKITMTQSIIPFNLMKVHLMVAVVGRLFQKWFPASPNLAYTFIWDKTDAYNQKV 1071
Query: 1128 YGLSDAVVSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHK 1187
YGLS+AVVSVG+EYE+C L LWEKRTA+LQG+ELD SN+GGW+LDKHH+L+V++GIL+K
Sbjct: 1072 YGLSEAVVSVGYEYESCLDLTLWEKRTAILQGYELDASNMGGWTLDKHHVLDVQNGILYK 1131
Query: 1188 GTGENQFLTQQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDF 1247
G GENQF++QQP +++SIMGNGRRRSISCPSCNG A+GNKLLAPVALA GIDGSLYVGDF
Sbjct: 1132 GNGENQFISQQPPVVSSIMGNGRRRSISCPSCNGQADGNKLLAPVALACGIDGSLYVGDF 1191
Query: 1248 NYIRRIFPSRNVTSILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSL 1307
NY+RRIFPS NVTS+LEL S+NPAH+YYLA DPV+G LYVSDTN+RRIYR KSL
Sbjct: 1192 NYVRRIFPSGNVTSVLEL-------SSNPAHRYYLATDPVTGDLYVSDTNTRRIYRPKSL 1244
Query: 1308 SGTKDLAGNSEVVAGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATM 1367
+G KDL N+EVVAGTGEQCLPFDEARCGDGGKA++ATLMSP+G+AVDKNGL+YFVD TM
Sbjct: 1245 TGAKDLTKNAEVVAGTGEQCLPFDEARCGDGGKAVEATLMSPKGMAVDKNGLIYFVDGTM 1304
Query: 1368 IRKVDQNGIISTLLGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNV 1427
IRKVDQNGIISTLLGSNDLT+ RPL+CD+SM ++QVRLEWPTDLA+NPMDNS+YVL+NNV
Sbjct: 1305 IRKVDQNGIISTLLGSNDLTSARPLTCDTSMHISQVRLEWPTDLAINPMDNSIYVLDNNV 1364
Query: 1428 ILRITENHQVSIIAGRPMHCQVPGIDYSLSKLAIHSALESASAIAISHTGVLYITETDEK 1487
+L+ITEN QV I AGRPMHCQVPG++Y + K A+ + LESA+AIA+S++GVLYITETDEK
Sbjct: 1365 VLQITENRQVRIAAGRPMHCQVPGVEYPVGKHAVQTTLESATAIAVSYSGVLYITETDEK 1424
Query: 1488 KINRLRQVTTNGEICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGT 1547
KINR+RQVTT+GEI L+AG S+CDCKND NC+CY D YA DA L++PSSLA +PDGT
Sbjct: 1425 KINRIRQVTTDGEISLVAGIPSECDCKNDANCDCYQSGDGYAKDAKLSAPSSLAASPDGT 1484
Query: 1548 IYIADLGNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYN 1607
+YIADLGNIRIRAVSKNKP+LN+ N YE ASP +QELY+F+ +G HQYTVSLVTG+YLYN
Sbjct: 1485 LYIADLGNIRIRAVSKNKPLLNSMNFYEVASPTDQELYIFDINGTHQYTVSLVTGDYLYN 1544
Query: 1608 FTYSTDNDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLE 1667
F+YS DND+T + D+NGN+L+IRRD + MP ++ PDNQ+I LT+GTNG LK ++ Q LE
Sbjct: 1545 FSYSNDNDITAVTDSNGNTLRIRRDPNRMPVRVVSPDNQVIWLTIGTNGCLKSMTAQGLE 1604
Query: 1668 LGLMTYDGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIE 1727
L L TY GN+GLLATKSDETGWTTF+DYD EGRLTNVT PTGVVT+LH +M+K+IT+DIE
Sbjct: 1605 LVLFTYHGNSGLLATKSDETGWTTFFDYDSEGRLTNVTFPTGVVTNLHGDMDKAITVDIE 1664
Query: 1728 NSNRDDDVTVITNLSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLA 1787
+S+R++DV++ +NLSS+++ YT+VQDQ+RNSYQ+ +G+LR++YA+G+ + +EPHVLA
Sbjct: 1665 SSSREEDVSITSNLSSIDSFYTMVQDQLRNSYQIGYDGSLRIIYASGLDSHYQTEPHVLA 1724
Query: 1788 GTITPTIGRCNISLPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIR 1847
GT PT+ + N++LP ENG N +EWR RKEQ +GKV +FGRKLRV+GRNLLS+D+DR +
Sbjct: 1725 GTANPTVAKRNMTLPGENGQNLVEWRFRKEQAQGKVNVFGRKLRVNGRNLLSVDFDRTTK 1784
Query: 1848 TEKIYDDHRKFTLRIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDID 1907
TEKIYDDHRKF LRI YD G P LWLPSS L AVNV+Y G++A +QRG SE+ D D
Sbjct: 1785 TEKIYDDHRKFLLRIAYDTSGHPTLWLPSSKLMAVNVTYSSTGQIASIQRGTTSEKVDYD 1844
Query: 1908 KQGRIVSRMFADGKVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVARHSMST 1967
QGRIVSR+FADGK WSY+YL+KSMVLLL SQRQYIFEYD DRL A+TMPSVARH+M T
Sbjct: 1845 GQGRIVSRVFADGKTWSYTYLEKSMVLLLHSQRQYIFEYDMWDRLSAITMPSVARHTMQT 1904
Query: 1968 HTSIGYIRNIYNPPESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDST 2027
SIGY RNIYNPPESNAS+I DY+++G +L+T+FLGT R+V +KY + ++LSEI+YDST
Sbjct: 1905 IRSIGYYRNIYNPPESNASIITDYNEEGLLLQTAFLGTSRRVLFKYRRQTRLSEILYDST 1964
Query: 2028 AVTFGYDETTGVLKMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDYTYHDN 2087
V+F YDET GVLK VNLQS GF CTIRYR+IGPL+D+QI+RFSE+GMVNARFDY+Y DN
Sbjct: 1965 RVSFTYDETAGVLKTVNLQSDGFICTIRYRQIGPLIDRQIFRFSEDGMVNARFDYSY-DN 2023
Query: 2088 SFRIASIKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDT 2147
SFR+ S++ VI+ETPLP+DLY++D+ISGKVE FGKFGVIYYDINQII+TAVMT +KHFD
Sbjct: 2024 SFRVTSMQGVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQIISTAVMTYTKHFDA 2083
Query: 2148 HGRIKEVQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAV 2207
HGRIKE+QYE+FRSLMYW+T+QYD+MGRV KRE+K+GP+ANTTKY Y+YD DGQLQ+V +
Sbjct: 2084 HGRIKEIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYAYEYDVDGQLQTVYL 2143
Query: 2208 NDRPTWRYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLCQRGSD 2267
N++ WRY+YDLNGNLHLLNP NS RL PLRYDLRDRITRLGDVQY++D+DG+L QRG++
Sbjct: 2144 NEKIMWRYNYDLNGNLHLLNPSNSARLTPLRYDLRDRITRLGDVQYRLDEDGFLRQRGTE 2203
Query: 2268 IFEYNSKGLLTRAYNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVY 2327
IFEY+SKGLLTR Y+K SGW+V YRYDG+GRR S KT+LG HLQ+FY+DL PTRITHVY
Sbjct: 2204 IFEYSSKGLLTRVYSKGSGWTVIYRYDGLGRRVSSKTSLGQHLQFFYADLTYPTRITHVY 2263
Query: 2328 NHSNSEITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGE 2387
NHS+SEITSLYYDLQGHLFAME SSG+E+Y+ASDNTGTPLAVFS NGLM+KQ+QYTAYGE
Sbjct: 2264 NHSSSEITSLYYDLQGHLFAMEISSGDEFYIASDNTGTPLAVFSSNGLMLKQIQYTAYGE 2323
Query: 2388 IYYDSNPDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKEPAPFN 2447
IY+DSN DFQ+VIGFHGGLYDPLTKL+HF +RDYD+LAGRWT+PD +WK +GK+PAPFN
Sbjct: 2324 IYFDSNIDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDIEIWKRIGKDPAPFN 2383
Query: 2448 LYMFKSNNPLSSELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYELSESQA 2507
LYMF++NNP S D+K+Y+TDV SWLV FGF L N IPGFP K P YEL +SQ
Sbjct: 2384 LYMFRNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKFDLTEPSYELVKSQQ 2443
Query: 2508 SENGQLITGVQQTTERHNQAFMAL----EGQVITKKLHASIREKAGHWFATTTPIIGKGI 2563
++ I GVQQ R +AF++L E QV ++ + ++ WFAT +IGKG+
Sbjct: 2444 WDDIPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRRAGGA---QSWLWFATVKSLIGKGV 2500
Query: 2564 MFAIKEGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLV 2623
M A+ +GRV T V +IA+ED KVA+VLNNA+YL+ +H++IEGKDTHYF+K + + DL
Sbjct: 2501 MLAVSQGRVQTNVLNIANEDCIKVAAVLNNAFYLENLHFTIEGKDTHYFIKTTTPESDLG 2560
Query: 2624 TLGTTIGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEK 2683
TL T GRK LE+G+NVTVSQ T +VNGRTRRF ++E Q+ L L +RYG+ TLDEEK
Sbjct: 2561 TLRLTSGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALALHVRYGM---TLDEEK 2617
Query: 2684 ARVLDQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQ 2743
AR+L+QARQRAL AWA+EQQ+ RDG EG+RLWTEGEK+QLLS G+VQGY+GYYVL VEQ
Sbjct: 2618 ARILEQARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKVQGYDGYYVLSVEQ 2677
Query: 2744 YPELADSSSNIQFLRQNEMGKR 2765
YPELADS++NIQFLRQ+E+G+R
Sbjct: 2678 YPELADSANNIQFLRQSEIGRR 2699
>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
Length = 2769
Score = 3536 bits (9168), Expect = 0.0
Identities = 1677/2633 (63%), Positives = 2071/2633 (78%), Gaps = 100/2633 (3%)
Query: 221 NSYLLRACSGPQQASSSGPPNHHSQSTLRPPLPP-PHNHTLSHHHS-SANSLNRNSLTNR 278
NS L + + + P + + LR P PP H HT + HH+ S NSLNR + T R
Sbjct: 149 NSNLTLTDTEHENTETDHPGGLQNHARLRTPPPPLSHAHTPNQHHAASINSLNRGNFTPR 208
Query: 279 RSQIHAPAPAPNDLATTP------ESVQLQDSWVLNSNVPLETR---------------- 316
+ +PAP + L+ P E Q++W+LNSN+PLETR
Sbjct: 209 SNP--SPAPTDHSLSGEPPAGGAQEPAHAQENWLLNSNIPLETRNLGKQPFLGTLQDNLI 266
Query: 317 -----------------HFLFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSR 359
HFLFK G++PLF ++SPGYPLTS TVY+PPPR LPR+TF+R
Sbjct: 267 EMDILGASRHDGAYSDGHFLFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFAR 325
Query: 360 KAFKLKKPSKYCSWKCAALSAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFN--NG 417
AF LKKPSKYC+WKCAALSAI + L ILLAYF+AMHL GLNW LQP +G +
Sbjct: 326 PAFNLKKPSKYCNWKCAALSAIVISATLVILLAYFVAMHLFGLNWHLQPMEGQMYEITED 385
Query: 418 IRTGLPGNDDVATMPSGGK---------------VPWSL--KNSSIDSGEAEVGRRVTQE 460
+ P DV+ PSGG P S ++S IDSGE +VGRR +Q+
Sbjct: 386 TASSWPVPTDVSLYPSGGTGLETPDRKGKGTTEGKPSSFFPEDSFIDSGEIDVGRRASQK 445
Query: 461 VPPGVFWRSQIHISQPQFLKFNISLGKDALFGVYIRRGLPPSHAQYDFMERLDGK----- 515
+PPG FWRSQ+ I P LKFN+SLGK AL G+Y R+GLPPSH Q+DF+E LDG+
Sbjct: 446 IPPGTFWRSQVFIDHPVHLKFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQ 505
Query: 516 EKWSVVESPRERRSIQTLVQNEAVFVQYLDVGLWHLAFYNDGKDKEMVSFNTVVLDSVQD 575
E S+ +PR+ R +E F+QYLD G+WHLAFYNDGK+ E+VSF T ++SV +
Sbjct: 506 EARSLEGTPRQSRGTVPPSSHETGFIQYLDSGIWHLAFYNDGKESEVVSFLTTAIESVDN 565
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
CP NC+GNG+C+SG CHCF GFLG DC +A+CPVLCSGNGQY KG C C+SGWKGAECDV
Sbjct: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
Query: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
P NQCID +C HG+CI G C+C+ GYKGE CEEVDC+DPTCS GVCV GEC CS GWG
Sbjct: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWG 685
Query: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
G NCE R C DQCSGHGT+LPDTGLCSCDP+W G DCS+E+C+ DCG HGVC+GG CR
Sbjct: 686 GTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCR 745
Query: 756 CEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTI---------DGCPDLCN 806
CE+GW GAACDQR CHPRC EHGTC+DGKCEC GWNGEHCTI +GCP LCN
Sbjct: 746 CEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCN 805
Query: 807 GNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQN 866
GNGRCTL N W CVCQ GWRG GC+ +MET+C D+KDN+GDGLVDC+DPDCCLQ C
Sbjct: 806 GNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHI 865
Query: 867 SLLCRGSRDPLDIIQQGQT--DWPAVKSFYDRIKLLAGKDSTHIIPGENPFNSSLVSLIR 924
+ LC GS +PLDIIQ+ Q + SFYDRIK L G+DSTHIIPGENPF+ +IR
Sbjct: 866 NPLCLGSPNPLDIIQETQVPVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIR 925
Query: 925 GQVVTTDGTPLVGVNVSFVKYPKYGYTITRQDGTFDLIANGGASLTLHFERAPFMSQERT 984
GQV+T+DGTPLVGVN+SFV P +GYTI+RQDG+FDL+ NGG S+ L FERAPF++QE T
Sbjct: 926 GQVMTSDGTPLVGVNISFVNNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHT 985
Query: 985 VWLPWNSFYAMDTLVMKTEENSIPSCDLSGFVRPDPIIISSPLSTFFSAAPGQNPIVPET 1044
+WLPW+ F+ M+T++M+ EEN IPSCDLS F RP+P++ SPL++F S+ + PIVPE
Sbjct: 986 LWLPWDRFFVMETIIMRHEENEIPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEI 1045
Query: 1045 QVLHEEIELPGSNVKLRYLSSRTAGYKSLLKITMTQSTVPLNLIRVHLMVAVEGHLFQKS 1104
Q L EEI + G ++L YLSSRT GYKS+L+I++T T+P NL++VHLMVAVEG LF+K
Sbjct: 1046 QALQEEISISGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKW 1105
Query: 1105 FQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVGFEYETCPSLILWEKRTALLQGFELDP 1164
F A+P+L+Y FIWDKTD Y Q+V+GLS+A VSVG+EYE+CP LILWEKRT +LQG+E+D
Sbjct: 1106 FAAAPDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTTVLQGYEIDA 1165
Query: 1165 SNLGGWSLDKHHILNVKSGILHKGTGENQFLTQQPAIITSIMGNGRRRSISCPSCNGLAE 1224
S LGGWSLDKHH LN++SGILHKG GENQF++QQP +I SIMGNGRRRSISCPSCNGLA+
Sbjct: 1166 SKLGGWSLDKHHALNIQSGILHKGNGENQFVSQQPPVIGSIMGNGRRRSISCPSCNGLAD 1225
Query: 1225 GNKLLAPVALAVGIDGSLYVGDFNYIRRIFPSRNVTSILELRNKEFKHSNNPAHKYYLAV 1284
GNKLLAPVAL G DGSLYVGDFNYIRRIFPS NVT+ILELRNK+F+HS++PAHKYYLA
Sbjct: 1226 GNKLLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILELRNKDFRHSHSPAHKYYLAT 1285
Query: 1285 DPVSGSLYVSDTNSRRIYRVKSLSGTKDLAGNSEVVAGTGEQCLPFDEARCGDGGKAIDA 1344
DP+SG++++SD+NSRR++++KS KDL NSEVVAGTG+QCLPFD+ RCGDGGKA +A
Sbjct: 1286 DPMSGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEA 1345
Query: 1345 TLMSPRGIAVDKNGLMYFVDATMIRKVDQNGIISTLLGSNDLTAVRPLSCDSSMDVAQVR 1404
TL +PRGI VDK GL+YFVD TMIR++DQNGIISTLLGSNDLT+ RPLSCDS MD++QV
Sbjct: 1346 TLTNPRGITVDKFGLIYFVDGTMIRRIDQNGIISTLLGSNDLTSARPLSCDSVMDISQVH 1405
Query: 1405 LEWPTDLAVNPMDNSLYVLENNVILRITENHQVSIIAGRPMHCQVPGID-YSLSKLAIHS 1463
LEWPTDLA+NPMDNSLYVL+NNV+L+I+ENHQV I+AGRPMHCQVPGID + LSK+AIH+
Sbjct: 1406 LEWPTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHA 1465
Query: 1464 ALESASAIAISHTGVLYITETDEKKINRLRQVTTNGEICLLAGAASDCDCKNDVNCNCYS 1523
LESA+A+A+SH GVLYI ETDEKKINR+RQVTT+GEI L+AGA S CDCKND NC+C+S
Sbjct: 1466 TLESATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFS 1525
Query: 1524 GDDAYATDAILNSPSSLAVAPDGTIYIADLGNIRIRAVSKNKPVLNAFNQYEAASPGEQE 1583
GDD YA DA LN+PSSLAV DG +Y+ADLGNIRIR + KNKP LN N YE +SP +QE
Sbjct: 1526 GDDGYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQE 1585
Query: 1584 LYVFNADGIHQYTVSLVTGEYLYNFTYSTDNDVTELIDNNGNSLKIRRDSSGMPRHLLMP 1643
LY+F+ G H YT SL TG+YLYNFTY+ D D+T + DNNGN + +RRDS+GMP L++P
Sbjct: 1586 LYLFDTTGKHLYTQSLPTGDYLYNFTYTGDGDITLITDNNGNMVNVRRDSTGMPLWLVVP 1645
Query: 1644 DNQIITLTVGTNGGLKVVSTQNLELGLMTYDGNTGLLATKSDETGWTTFYDYDHEGRLTN 1703
D Q+ +T+GTN LK V+TQ EL +MTY GN+GLLATKS+E GWTTFY+YD GRLTN
Sbjct: 1646 DGQVYWVTMGTNSALKSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTN 1705
Query: 1704 VTRPTGVVTSLHREMEKSITIDIENSNRDDDVTVITNLSSVEASYTVVQDQVRNSYQLCN 1763
VT PTG V+S + + S+ + +E S++ DDVT+ TNLS+ A YT++QDQVRNSY +
Sbjct: 1706 VTFPTGQVSSFRSDTDSSVHVQVETSSK-DDVTITTNLSASGAFYTLLQDQVRNSYYIGA 1764
Query: 1764 NGTLRVMYANGMGISFHSEPHVLAGTITPTIGRCNISLPMENGLNSIEWRLRKEQIKGKV 1823
+G+LR++ ANGM ++ +EPH+LAGT+ PT+G+ N++LP++NGLN +EWR RKEQ +G+V
Sbjct: 1765 DGSLRLLLANGMEVALQTEPHLLAGTVNPTVGKRNVTLPIDNGLNLVEWRQRKEQARGQV 1824
Query: 1824 TIFGRKLRVHGRNLLSIDYDRNIRTEKIYDDHRKFTLRIIYDQVGRPFLWLPSSGLAAVN 1883
T+FGR+LRVH RNLLS+D+DR RTEKIYDDHRKFTLRI+YDQ GRP LW PSS L VN
Sbjct: 1825 TVFGRRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPSLWSPSSRLNGVN 1884
Query: 1884 VSYFFNGRLAGLQRGAMSERTDIDKQGRIVSRMFADGKVWSYSYLDKSMVLLLQSQRQYI 1943
V+Y G +AG+QRG MSER + D+ GRI SR+FADGK WSY+YL+KSMVLLL SQRQYI
Sbjct: 1885 VTYSPGGYIAGIQRGIMSERMEYDQAGRITSRIFADGKTWSYTYLEKSMVLLLHSQRQYI 1944
Query: 1944 FEYDSSDRLLAVTMPSVARHSMSTHTSIGYIRNIYNPPESNASVIFDYSDDGRILKTSFL 2003
FE+D +DRL +VTMP+VAR ++ T S+GY RNIY PPE NASVI D+++DG +L T +L
Sbjct: 1945 FEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEGNASVIQDFTEDGHLLHTFYL 2004
Query: 2004 GTGRQVFYKYGKLSKLSEIVYDSTAVTFGYDETTGVLKMVNLQSGGFSCTIRYRKIGPLV 2063
GTGR+V YKYGKLSKL+E +YD+T V+F YDET G+LK +NLQ+ GF+CTIRYR+IGPL+
Sbjct: 2005 GTGRRVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKTINLQNEGFTCTIRYRQIGPLI 2064
Query: 2064 DKQIYRFSEEGMVNARFDYTYHDNSFRIASIKPVISETPLPVDLYRYDEISGKVEHFGKF 2123
D+QI+RF+EEGMVNARFDY Y DNSFR+ S++ VI+ETPLP+DLYRYD++SGK E FGKF
Sbjct: 2065 DRQIFRFTEEGMVNARFDYNY-DNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKF 2123
Query: 2124 GVIYYDINQIITTAVMTLSKHFDTHGRIKEVQYEMFRSLMYWMTVQYDSMGRVIKRELKL 2183
GVIYYDINQIITTAVMT +KHFD +GR+KEVQYE+FRSLMYWMTVQYD+MGRV+K+ELK+
Sbjct: 2124 GVIYYDINQIITTAVMTHTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKV 2183
Query: 2184 GPYANTTKYTYDYDGDGQLQSVAVNDRPTWRYSYDLNGNLHLLNPGNSVRLMPLRYDLRD 2243
GPYANTT+Y+Y+YD DGQLQ+V++ND+P WRYSYDLNGNLHLL+PGNS RL PLRYD+RD
Sbjct: 2184 GPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRD 2243
Query: 2244 RITRLGDVQYKIDDDGYLCQRGSDIFEYNSKGLLTRAYNKASGWSVQYRYDGVGRRASYK 2303
RITRLGDVQYK+D+DG+L QRG DIFEYNS GLL +AYN+A WSV+YRYDG+GRR S K
Sbjct: 2244 RITRLGDVQYKMDEDGFLRQRGGDIFEYNSAGLLIKAYNRAGSWSVRYRYDGLGRRVSSK 2303
Query: 2304 TNLGHHLQYFYSDLHNPTRITHVYNHSNSEITSLYYDLQGHLFAMESSSGEEYYVASDNT 2363
++ HHLQ+FY+DL NPT++TH+YNHS+SEITSLYYDLQGHLFAME SSG+E+Y+A DN
Sbjct: 2304 SSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNI 2363
Query: 2364 GTPLAVFSINGLMIKQLQYTAYGEIYYDSNPDFQMVIGFHGGLYDPLTKLVHFTQRDYDV 2423
GTPLAVFS GLMIKQ+ YTAYGEIY D+NP+FQ++IG+HGGLYDPLTKLVH +RDYDV
Sbjct: 2364 GTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDV 2423
Query: 2424 LAGRWTSPDYTMWKNVGKEPA-PFNLYMFKSNNPLSSELDLKNYVTDVKSWLVMFGFQLS 2482
LAGRWTSPD+ +WK++ PFNLYMFK+NNP+S+ D+K ++TDV SWL+ FGFQL
Sbjct: 2424 LAGRWTSPDHELWKHLSSSNVMPFNLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLH 2483
Query: 2483 NIIPGFPRAKMYFVPPPYELSESQAS----ENGQLITGVQQTTERHNQAFMALE------ 2532
N+IPG+P+ M + P YEL +Q +N + I GVQ ++ +AF+ LE
Sbjct: 2484 NVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLY 2543
Query: 2533 GQVITKKLHASIREKAGHWFATTTPIIGKGIMFAIKEGRVTTGVSSIASEDSRKVASVLN 2592
G IT A +K FA++ + GKG+ FA+K+GRVTT + S+A+ED R+VA++LN
Sbjct: 2544 GSTITSCQQAPKTKK----FASSGSVFGKGVKFALKDGRVTTDIISVANEDGRRVAAILN 2599
Query: 2593 NAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGTTIGRKVLESGVNVTVSQPTLLVNGR 2652
+A+YL+ +H++I+G DTHYFVK G ++GDL LG + GR+ LE+GVNVTVSQ ++NGR
Sbjct: 2600 HAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLENGVNVTVSQINTVLNGR 2659
Query: 2653 TRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVLDQARQRALGTAWAKEQQKARDGREG 2712
TRR+T+I+ QY L L+ RYG TLDEEKARVL+ ARQRA+ AWA+EQQ+ R+G EG
Sbjct: 2660 TRRYTDIQLQYGALCLNTRYG---TTLDEEKARVLELARQRAVRQAWAREQQRLREGEEG 2716
Query: 2713 SRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPELADSSSNIQFLRQNEMGKR 2765
R WTEGEKQQ+LSTGRVQGY+G++V+ VEQYPEL+DS++NI F+RQ+EMG+R
Sbjct: 2717 LRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHFMRQSEMGRR 2769
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 3301 bits (8560), Expect = 0.0
Identities = 1590/2778 (57%), Positives = 2056/2778 (74%), Gaps = 102/2778 (3%)
Query: 22 YTSSSLDSEDCRVPTQKSYSSSETLKAYDHDSRMHYGNRVTDLIHRESDEFPRQGTNFTL 81
YTSSS +SED R P Q SY+S ETL Y+ + RM+Y S R+ +
Sbjct: 23 YTSSSDESEDGRKPRQ-SYNSRETLHEYNQELRMNYN----------SQSRKRKEVEKST 71
Query: 82 AELGICEPSPHR-SGYCSDM-GILHQGYSLSTGSDADSDTEGGMSPEHAIRLWGRGIKSR 139
E+ CE S SGY +DM + GY L GSD D++TEG SP+HA+R+W RG+KS
Sbjct: 72 QEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSE 131
Query: 140 RSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPSLLPSAQLPSSHNPPPVSCQMP 199
SS LSSR NSAL+LTD+D+E KSD ENG PV C M
Sbjct: 132 HSSCLSSRANSALSLTDTDHERKSDGENGFKF--------------------SPVCCDM- 170
Query: 200 LLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSGPPNHHSQSTLRPPLPPPHNHT 259
A +G Q S P N + L PP PPPH T
Sbjct: 171 --------------------------EAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACT 204
Query: 260 LSHH-HSSANSLNRNSLTNRRSQIHAPAPAPNDLATTPESVQLQDSWVLNSNVPLETRHF 318
+ +A+SL R S+T RSQ APAP +T +SV L +SWVLNSN+PLETRHF
Sbjct: 205 CARKPPPAADSLQRRSMTT-RSQPSPAAPAPP--TSTQDSVHLHNSWVLNSNIPLETRHF 261
Query: 319 LFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRKAFKLKKPSKYCSWKCAAL 378
LFK SGS+ +FS++S YPLTS TVY+PPPR LPR+TFSR AF KP + C+WKC AL
Sbjct: 262 LFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTAL 321
Query: 379 SAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFNNGIRTGLPGND--DVATMPSGGK 436
SA A + LA+LLAY IA+HL GL WQLQP +G + NG+ G G + D P GGK
Sbjct: 322 SATAITVTLALLLAYVIAVHLFGLTWQLQPVEGELYANGVSKGNRGTESMDTTYSPIGGK 381
Query: 437 VPWS------LKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLKFNISLGKDAL 490
V K +ID+GE ++G +V Q +PPG+FWR QI I P +LKFNISL KD+L
Sbjct: 382 VSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSL 441
Query: 491 FGVYIRRGLPPSHAQYDFMERLDGKE------KWSVVESPRERRSIQTLVQNEAVFVQYL 544
G+Y RR +PP+H Q+DF++ +DGK+ K S R I T +Q E F++Y+
Sbjct: 442 LGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQ-ETGFIEYM 500
Query: 545 DVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGADCAK 604
D G W+LAFYNDGK E V T ++ + DC NC+GNGEC+SG CHCFPGFLG DCA+
Sbjct: 501 DQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCAR 560
Query: 605 AACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKG 664
+CPVLC GNG+Y KG C C GWKG ECDVP QCIDP+C GHG+CI G C+C GYKG
Sbjct: 561 DSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKG 620
Query: 665 EHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCS 724
E CEE DCLDP CS+HG+CV GEC CS GWGG+NCE C +QCSGHGT+L D G+CS
Sbjct: 621 EICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCS 680
Query: 725 CDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGK 784
CDP W G DCS E+C+++CG+HGVC G C+CEEGW G C++R CH C EHG CKDGK
Sbjct: 681 CDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGK 740
Query: 785 CECREGWNGEHCTI--------DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME 836
CEC GW G+HCTI DGCP LC GNGRCTL QN W CVCQ GW G GCNV ME
Sbjct: 741 CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVME 800
Query: 837 TSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQTDWPAVKS--FY 894
C DN DN+GDGL DC+DPDCC QS C S LC+GS DPLD+IQQ QT + S FY
Sbjct: 801 MLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFY 860
Query: 895 DRIKLLAGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITR 954
DRIK L GKDSTH+IP E F+S +IRGQVV DGTPLVGVNVSF+ + YG+TI+R
Sbjct: 861 DRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISR 920
Query: 955 QDGTFDLIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENSIPSCDLSG 1014
QDG+FDL+A GG S+ L F+R+PF+ ++RT+WLPWN F ++ + M+ + PSCD+S
Sbjct: 921 QDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVVSDPPSCDISN 980
Query: 1015 FVRPDPIIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLL 1074
F+ P+PI++ SPL++F + P + IVPE QV+ EEI +P S V+L YLSSRT GYK+LL
Sbjct: 981 FISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLL 1040
Query: 1075 KITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAV 1134
+I +T ST+P+ +I+VHL VAVEG L QK F A+ NL YTF W+KTD YGQ+V+GL++A+
Sbjct: 1041 RILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEAL 1100
Query: 1135 VSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQF 1194
VSVG+EYETCP ILWE+RT +LQGFE+D SNLGGWSL+KHHILN +SGI+HKG GEN F
Sbjct: 1101 VSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMF 1160
Query: 1195 LTQQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIF 1254
++QQP +I++IMGNG +RS++C +CNG A NKL APVALA G DGS+YVGDFN++RRIF
Sbjct: 1161 ISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIF 1220
Query: 1255 PSRNVTSILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLA 1314
PS N SILELRN++ +HS +PAHKYYLA+DPVS SLY+SDTN+R++Y++KSL TKDL+
Sbjct: 1221 PSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLS 1280
Query: 1315 GNSEVVAGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQN 1374
N EVVAGTG+QCLPFD++ CGDGG+A +A+L SPRGI VD++G +YFVD TMIRK+D+N
Sbjct: 1281 KNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDEN 1340
Query: 1375 GIISTLLGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITEN 1434
+I+T++GSN LT+ +PLSCDS MD+ QVRLEWPTDLAVNPMDNSLYVL+NN++L+I+EN
Sbjct: 1341 AVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISEN 1400
Query: 1435 HQVSIIAGRPMHCQVPGIDYSL-SKLAIHSALESASAIAISHTGVLYITETDEKKINRLR 1493
+V IIAGRP+HCQVPGID+ L SK+AIHS LESA AI++SH+G+L+I ETDE+K+NR++
Sbjct: 1401 RRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQ 1460
Query: 1494 QVTTNGEICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADL 1553
QVTTNGEI ++AGA +DCDCK D NC+C+SGD YA DA + +PSSLAV+PDGT+Y+ADL
Sbjct: 1461 QVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADL 1520
Query: 1554 GNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSTD 1613
GN+RIR +S+N+ LN N YE ASP +QELY F +G H +T++L+T +Y+YNFTY+++
Sbjct: 1521 GNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNSE 1580
Query: 1614 NDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTY 1673
D+ + +NGNS+ IRRD+ GMP L++P Q+ LT+ +NG LK VS Q L LMTY
Sbjct: 1581 GDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTY 1640
Query: 1674 DGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDD 1733
GNTGLLATKS+E GWTT Y+YD EG LTN T PTG V+S H ++EK ++++ SNR +
Sbjct: 1641 PGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNR-E 1699
Query: 1734 DVTVITNLSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLAGTITPT 1793
+V + TNL++ Y + Q+ +++Y++ +G+LRV +A+GM I SEPH+LAG + PT
Sbjct: 1700 NVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPT 1759
Query: 1794 IGRCNISLPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYD 1853
+G+CNISLP E+ N IEWR RKEQ KG V+ F R+LR H RNLLSID+D RT KIYD
Sbjct: 1760 LGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYD 1819
Query: 1854 DHRKFTLRIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIV 1913
DHRKFTLRI+YDQ GRP LW P S VN++Y +G + +QRG +E+ + D+ G+I+
Sbjct: 1820 DHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKII 1879
Query: 1914 SRMFADGKVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVARHSMSTHTSIGY 1973
SR +ADGK+WSY+YL+KS++LLL SQR+YIFEYD D LL+VTMPS+ RHS+ T S+GY
Sbjct: 1880 SRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLSVTMPSMVRHSLQTMLSVGY 1939
Query: 1974 IRNIYNPPESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGY 2033
RNIY PP+S+ S I DYS DGR+L+T LGTGR+V YKY K ++LSE++YD+T VT Y
Sbjct: 1940 YRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYDTTQVTLTY 1999
Query: 2034 DETTGVLKMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDYTYHDNSFRIAS 2093
+E++GV+K ++L GF CTIRYR+ GPL+ +QI+RFSEEG+VNARFDY+Y N+FR+ S
Sbjct: 2000 EESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSY--NNFRVTS 2057
Query: 2094 IKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDTHGRIKE 2153
++ VI+ETPLP+DLYRY ++SG+ E FGKF VI YD+NQ+ITT VM +K F +G++ E
Sbjct: 2058 MQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIE 2117
Query: 2154 VQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTW 2213
VQYE+ +++ YWMT+QYD++GR++ ++++G AN T+Y Y+YD DGQLQ+V+VND+ W
Sbjct: 2118 VQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQW 2177
Query: 2214 RYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLCQRGSDIFEYNS 2273
RYSYDLNGN++LL+ G S RL PLRYDLRDRITRLG++QYK+D+DG+L QRG+DIFEYNS
Sbjct: 2178 RYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNS 2237
Query: 2274 KGLLTRAYNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSE 2333
GLL +AYNKASGW+VQY YDG+GRR + K++LG HLQ+FY+DL NP R+TH+YNH++SE
Sbjct: 2238 NGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADLTNPIRVTHLYNHTSSE 2297
Query: 2334 ITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSN 2393
ITSLYYDLQGHL AME SSGEEYYVA DNTGTPLAVFS G +IK++ YT YG+IY+D+
Sbjct: 2298 ITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTY 2357
Query: 2394 PDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKEPAPFNLYMFKS 2453
PDFQ++IGFHGGLYD LTKLVH QRDYDV+AGRWT+P++ +WK + P PFNLY F++
Sbjct: 2358 PDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKQLNLLPKPFNLYSFEN 2417
Query: 2454 NNPLSSELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYEL----SESQASE 2509
N P+ D+ Y TD++SWL +FGFQL N++PGFP+ ++ + YEL +++Q +
Sbjct: 2418 NYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWD 2477
Query: 2510 NGQLITGVQQTTERHNQAFMALEGQVITKKLHASIREKAGHW--FATTTPIIGKGIMFAI 2567
G+ I G+Q ++ + F++L+ +T + + + G FA + GKGI FAI
Sbjct: 2478 PGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAI 2537
Query: 2568 KEGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGT 2627
K+G VT + +A+EDSR++A++LNNA+YL+ +H++IEG+DTHYF+K+GS + DLV +G
Sbjct: 2538 KDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGN 2597
Query: 2628 TIGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVL 2687
T GR++LE+GVNVTVSQ T ++NGRTRRF +I+ Q+ L +IRYG T++EEK VL
Sbjct: 2598 TGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYG---TTVEEEKNHVL 2654
Query: 2688 DQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPEL 2747
+ ARQRA+ AW KEQ++ ++G EG R WTEGEKQQLLSTGRVQGY+GY+VL VEQY EL
Sbjct: 2655 EIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLEL 2714
Query: 2748 ADSSSNIQFLRQNEMGKR 2765
+DS++NI F+RQ+E+G+R
Sbjct: 2715 SDSANNIHFMRQSEIGRR 2732
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 3295 bits (8544), Expect = 0.0
Identities = 1589/2778 (57%), Positives = 2055/2778 (73%), Gaps = 103/2778 (3%)
Query: 22 YTSSSLDSEDCRVPTQKSYSSSETLKAYDHDSRMHYGNRVTDLIHRESDEFPRQGTNFTL 81
YTSSS +SED R P Q SY+S ETL Y+ + RM+Y S R+ +
Sbjct: 23 YTSSSDESEDGRKPRQ-SYNSRETLHEYNQELRMNYN----------SQSRKRKEVEKST 71
Query: 82 AELGICEPSPHR-SGYCSDM-GILHQGYSLSTGSDADSDTEGGMSPEHAIRLWGRGIKSR 139
E+ CE S SGY +DM + GY L GSD D++TEG SP+HA+R+W RG+KS
Sbjct: 72 QEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSE 131
Query: 140 RSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPSLLPSAQLPSSHNPPPVSCQMP 199
SS LSSR NSAL+LTD+D+E KSD ENG PV C M
Sbjct: 132 HSSCLSSRANSALSLTDTDHERKSDGENGFKF--------------------SPVCCDM- 170
Query: 200 LLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSGPPNHHSQSTLRPPLPPPHNHT 259
A +G Q S P N + L PP PPPH T
Sbjct: 171 --------------------------EAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACT 204
Query: 260 LSHH-HSSANSLNRNSLTNRRSQIHAPAPAPNDLATTPESVQLQDSWVLNSNVPLETRHF 318
+ +A+SL R S+T RSQ APAP +T +SV L +SWVLNSN+PLETRHF
Sbjct: 205 CARKPPPAADSLQRRSMTT-RSQPSPAAPAPP--TSTQDSVHLHNSWVLNSNIPLETRHF 261
Query: 319 LFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRKAFKLKKPSKYCSWKCAAL 378
LFK SGS+ +FS++S YPLTS TVY+PPPR LPR+TFSR AF KP + C+WKC AL
Sbjct: 262 LFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTAL 321
Query: 379 SAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFNNGIRTGLPGND--DVATMPSGGK 436
SA A + LA+LLAY I +HL GL WQLQP +G + NG+ G G + D P GGK
Sbjct: 322 SATAITVTLALLLAYVI-VHLFGLTWQLQPVEGELYANGVSKGNRGTESMDTTYSPIGGK 380
Query: 437 VPWS------LKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLKFNISLGKDAL 490
V K +ID+GE ++G +V Q +PPG+FWR QI I P +LKFNISL KD+L
Sbjct: 381 VSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSL 440
Query: 491 FGVYIRRGLPPSHAQYDFMERLDGKE------KWSVVESPRERRSIQTLVQNEAVFVQYL 544
G+Y RR +PP+H Q+DF++ +DGK+ K S R I T +Q E F++Y+
Sbjct: 441 LGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQ-ETGFIEYM 499
Query: 545 DVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGADCAK 604
D G W+LAFYNDGK E V T ++ + DC NC+GNGEC+SG CHCFPGFLG DCA+
Sbjct: 500 DQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCAR 559
Query: 605 AACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKG 664
+CPVLC GNG+Y KG C C GWKG ECDVP QCIDP+C GHG+CI G C+C GYKG
Sbjct: 560 DSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKG 619
Query: 665 EHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCS 724
E CEE DCLDP CS+HG+CV GEC CS GWGG+NCE C +QCSGHGT+L D G+CS
Sbjct: 620 EICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCS 679
Query: 725 CDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGK 784
CDP W G DCS E+C+++CG+HGVC G C+CEEGW G C++R CH C EHG CKDGK
Sbjct: 680 CDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGK 739
Query: 785 CECREGWNGEHCTI--------DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME 836
CEC GW G+HCTI DGCP LC GNGRCTL QN W CVCQ GW G GCNV ME
Sbjct: 740 CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVME 799
Query: 837 TSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQTDWPAVKS--FY 894
C DN DN+GDGL DC+DPDCC QS C S LC+GS DPLD+IQQ QT + S FY
Sbjct: 800 MLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFY 859
Query: 895 DRIKLLAGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITR 954
DRIK L GKDSTH+IP E F+S +IRGQVV DGTPLVGVNVSF+ + YG+TI+R
Sbjct: 860 DRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISR 919
Query: 955 QDGTFDLIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENSIPSCDLSG 1014
QDG+FDL+A GG S+ L F+R+PF+ ++RT+WLPWN F ++ + M+ + PSCD+S
Sbjct: 920 QDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVVSDPPSCDISN 979
Query: 1015 FVRPDPIIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLL 1074
F+ P+PI++ SPL++F + P + IVPE QV+ EEI +P S V+L YLSSRT GYK+LL
Sbjct: 980 FISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLL 1039
Query: 1075 KITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAV 1134
+I +T ST+P+ +I+VHL VAVEG L QK F A+ NL YTF W+KTD YGQ+V+GL++A+
Sbjct: 1040 RILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEAL 1099
Query: 1135 VSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQF 1194
VSVG+EYETCP ILWE+RT +LQGFE+D SNLGGWSL+KHHILN +SGI+HKG GEN F
Sbjct: 1100 VSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMF 1159
Query: 1195 LTQQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIF 1254
++QQP +I++IMGNG +RS++C +CNG A NKL APVALA G DGS+YVGDFN++RRIF
Sbjct: 1160 ISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIF 1219
Query: 1255 PSRNVTSILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLA 1314
PS N SILELRN++ +HS +PAHKYYLA+DPVS SLY+SDTN+R++Y++KSL TKDL+
Sbjct: 1220 PSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLS 1279
Query: 1315 GNSEVVAGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQN 1374
N EVVAGTG+QCLPFD++ CGDGG+A +A+L SPRGI VD++G +YFVD TMIRK+D+N
Sbjct: 1280 KNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDEN 1339
Query: 1375 GIISTLLGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITEN 1434
+I+T++GSN LT+ +PLSCDS MD+ QVRLEWPTDLAVNPMDNSLYVL+NN++L+I+EN
Sbjct: 1340 AVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISEN 1399
Query: 1435 HQVSIIAGRPMHCQVPGIDYSL-SKLAIHSALESASAIAISHTGVLYITETDEKKINRLR 1493
+V IIAGRP+HCQVPGID+ L SK+AIHS LESA AI++SH+G+L+I ETDE+K+NR++
Sbjct: 1400 RRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQ 1459
Query: 1494 QVTTNGEICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADL 1553
QVTTNGEI ++AGA +DCDCK D NC+C+SGD YA DA + +PSSLAV+PDGT+Y+ADL
Sbjct: 1460 QVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADL 1519
Query: 1554 GNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSTD 1613
GN+RIR +S+N+ LN N YE ASP +QELY F +G H +T++L+T +Y+YNFTY+++
Sbjct: 1520 GNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNSE 1579
Query: 1614 NDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTY 1673
D+ + +NGNS+ IRRD+ GMP L++P Q+ LT+ +NG LK VS Q L LMTY
Sbjct: 1580 GDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTY 1639
Query: 1674 DGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDD 1733
GNTGLLATKS+E GWTT Y+YD EG LTN T PTG V+S H ++EK ++++ SNR +
Sbjct: 1640 PGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNR-E 1698
Query: 1734 DVTVITNLSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLAGTITPT 1793
+V + TNL++ Y + Q+ +++Y++ +G+LRV +A+GM I SEPH+LAG + PT
Sbjct: 1699 NVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPT 1758
Query: 1794 IGRCNISLPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYD 1853
+G+CNISLP E+ N IEWR RKEQ KG V+ F R+LR H RNLLSID+D RT KIYD
Sbjct: 1759 LGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYD 1818
Query: 1854 DHRKFTLRIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIV 1913
DHRKFTLRI+YDQ GRP LW P S VN++Y +G + +QRG +E+ + D+ G+I+
Sbjct: 1819 DHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKII 1878
Query: 1914 SRMFADGKVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVARHSMSTHTSIGY 1973
SR +ADGK+WSY+YL+KS++LLL SQR+YIFEYD D LL+VTMPS+ RHS+ T S+GY
Sbjct: 1879 SRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLSVTMPSMVRHSLQTMLSVGY 1938
Query: 1974 IRNIYNPPESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGY 2033
RNIY PP+S+ S I DYS DGR+L+T LGTGR+V YKY K ++LSE++YD+T VT Y
Sbjct: 1939 YRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYDTTQVTLTY 1998
Query: 2034 DETTGVLKMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDYTYHDNSFRIAS 2093
+E++GV+K ++L GF CTIRYR+ GPL+ +QI+RFSEEG+VNARFDY+Y N+FR+ S
Sbjct: 1999 EESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSY--NNFRVTS 2056
Query: 2094 IKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDTHGRIKE 2153
++ VI+ETPLP+DLYRY ++SG+ E FGKF VI YD+NQ+ITT VM +K F +G++ E
Sbjct: 2057 MQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIE 2116
Query: 2154 VQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTW 2213
VQYE+ +++ YWMT+QYD++GR++ ++++G AN T+Y Y+YD DGQLQ+V+VND+ W
Sbjct: 2117 VQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQW 2176
Query: 2214 RYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLCQRGSDIFEYNS 2273
RYSYDLNGN++LL+ G S RL PLRYDLRDRITRLG++QYK+D+DG+L QRG+DIFEYNS
Sbjct: 2177 RYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNS 2236
Query: 2274 KGLLTRAYNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSE 2333
GLL +AYNKASGW+VQY YDG+GRR + K++LG HLQ+FY+DL NP R+TH+YNH++SE
Sbjct: 2237 NGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADLTNPIRVTHLYNHTSSE 2296
Query: 2334 ITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSN 2393
ITSLYYDLQGHL AME SSGEEYYVA DNTGTPLAVFS G +IK++ YT YG+IY+D+
Sbjct: 2297 ITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTY 2356
Query: 2394 PDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKEPAPFNLYMFKS 2453
PDFQ++IGFHGGLYD LTKLVH QRDYDV+AGRWT+P++ +WK + P PFNLY F++
Sbjct: 2357 PDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKQLNLLPKPFNLYSFEN 2416
Query: 2454 NNPLSSELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYEL----SESQASE 2509
N P+ D+ Y TD++SWL +FGFQL N++PGFP+ ++ + YEL +++Q +
Sbjct: 2417 NYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWD 2476
Query: 2510 NGQLITGVQQTTERHNQAFMALEGQVITKKLHASIREKAGHW--FATTTPIIGKGIMFAI 2567
G+ I G+Q ++ + F++L+ +T + + + G FA + GKGI FAI
Sbjct: 2477 PGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAI 2536
Query: 2568 KEGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGT 2627
K+G VT + +A+EDSR++A++LNNA+YL+ +H++IEG+DTHYF+K+GS + DLV +G
Sbjct: 2537 KDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGN 2596
Query: 2628 TIGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVL 2687
T GR++LE+GVNVTVSQ T ++NGRTRRF +I+ Q+ L +IRYG T++EEK VL
Sbjct: 2597 TGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYG---TTVEEEKNHVL 2653
Query: 2688 DQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPEL 2747
+ ARQRA+ AW KEQ++ ++G EG R WTEGEKQQLLSTGRVQGY+GY+VL VEQY EL
Sbjct: 2654 EIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLEL 2713
Query: 2748 ADSSSNIQFLRQNEMGKR 2765
+DS++NI F+RQ+E+G+R
Sbjct: 2714 SDSANNIHFMRQSEIGRR 2731
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 3286 bits (8519), Expect = 0.0
Identities = 1587/2778 (57%), Positives = 2050/2778 (73%), Gaps = 109/2778 (3%)
Query: 22 YTSSSLDSEDCRVPTQKSYSSSETLKAYDHDSRMHYGNRVTDLIHRESDEFPRQGTNFTL 81
YTSSS +SED R P Q SY+S ETL Y+ + RM+Y S R+ +
Sbjct: 23 YTSSSDESEDGRKPRQ-SYNSRETLHEYNQELRMNYN----------SQSRKRKEVEKST 71
Query: 82 AELGICEPSPHR-SGYCSDM-GILHQGYSLSTGSDADSDTEGGMSPEHAIRLWGRGIKSR 139
E+ CE S SGY +DM + GY L GSD D++TEG SP+HA+R+W RG+KS
Sbjct: 72 QEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSE 131
Query: 140 RSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPSLLPSAQLPSSHNPPPVSCQMP 199
SS LSSR NSAL+LTD+D+E KSD ENG PV C M
Sbjct: 132 HSSCLSSRANSALSLTDTDHERKSDGENGFKF--------------------SPVCCDM- 170
Query: 200 LLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSGPPNHHSQSTLRPPLPPPHNHT 259
A +G Q S P N + L PP PPPH T
Sbjct: 171 --------------------------EAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACT 204
Query: 260 LSHH-HSSANSLNRNSLTNRRSQIHAPAPAPNDLATTPESVQLQDSWVLNSNVPLETRHF 318
+ +A+SL R S+T RSQ APAP +T +SV L +SWVLNSN+PLETRHF
Sbjct: 205 CARKPPPAADSLQRRSMTT-RSQPSPAAPAPP--TSTQDSVHLHNSWVLNSNIPLETRHF 261
Query: 319 LFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRKAFKLKKPSKYCSWKCAAL 378
LFK SGS+ +FS++S YPLTS TVY+PPPR LPR+TFSR AF KP + C+WKC AL
Sbjct: 262 LFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTAL 321
Query: 379 SAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFNNGIRTGLPGND--DVATMPSGGK 436
SA A + LA+LLAY IA+HL GL WQLQP +G + NG+ G G + D P GGK
Sbjct: 322 SATAITVTLALLLAYVIAVHLFGLTWQLQPVEGELYANGVSKGNRGTESMDTTYSPIGGK 381
Query: 437 VPWS------LKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLKFNISLGKDAL 490
V K +ID+GE ++G +V Q +PPG+FWR QI I P +LKFNISL KD+L
Sbjct: 382 VSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSL 441
Query: 491 FGVYIRRGLPPSHAQYDFMERLDGKE------KWSVVESPRERRSIQTLVQNEAVFVQYL 544
G+Y RR +PP+H Q+DF++ +DGK+ K S R I T +Q E F++Y+
Sbjct: 442 LGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQ-ETGFIEYM 500
Query: 545 DVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGADCAK 604
D G W+LAFYNDGK E V T ++ + DC NC+GNGEC+SG CHCFPGFLG DCA+
Sbjct: 501 DQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCAR 560
Query: 605 AACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKG 664
+CPVLC GNG+Y KG C C GWKG ECDVP QCIDP+C GHG+CI G C+C GYKG
Sbjct: 561 DSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKG 620
Query: 665 EHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCS 724
E CEE DCLDP CS+HG+CV GEC CS GWGG+NCE C +QCSGHGT+L D G+CS
Sbjct: 621 EICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCS 680
Query: 725 CDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGK 784
CDP W G DCS E+C+++CG+HGVC G C+CEEGW G C++R CH C EHG CKDGK
Sbjct: 681 CDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGK 740
Query: 785 CECREGWNGEHCTI--------DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME 836
CEC GW G+HCTI DGCP LC GNGRCTL QN W CVCQ GW G GCNV ME
Sbjct: 741 CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVME 800
Query: 837 TSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQTDWPAVKS--FY 894
C DN DN+GDGL DC+DPDCC QS C S LC+GS DPLD+IQQ QT + S FY
Sbjct: 801 MLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFY 860
Query: 895 DRIKLLAGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITR 954
DRIK L GKDSTH+IP E F+S +IRGQVV DGTPLVGVNVSF+ + YG+TI+R
Sbjct: 861 DRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISR 920
Query: 955 QDGTFDLIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENSIPSCDLSG 1014
QDG+FDL+A GG S+ L F+R+PF+ ++RT+WLPWN F ++ + M+ + PSCD+S
Sbjct: 921 QDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVVSDPPSCDISN 980
Query: 1015 FVRPDPIIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLL 1074
F+ P+PI++ SPL++F + P + IVPE QV+ EEI +P S V+L YLSSRT GYK+LL
Sbjct: 981 FISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLL 1040
Query: 1075 KITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAV 1134
+I +T ST+P+ +I+VHL VAVEG L QK F A+ NL YTF W+KTD YGQ+V+GL++A+
Sbjct: 1041 RILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEAL 1100
Query: 1135 VSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQF 1194
VSVG+EYETCP ILWE+RT +LQGFE+D SNLGGWSL+KHHILN +SGI+HKG GEN F
Sbjct: 1101 VSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMF 1160
Query: 1195 LTQQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIF 1254
++QQP +I++IMGNG +RS++C +CNG A NKL APVALA G DGS+YVGDFN++RRIF
Sbjct: 1161 ISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIF 1220
Query: 1255 PSRNVTSILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLA 1314
PS N SILEL S +PAHKYYLA+DPVS SLY+SDTN+R++Y++KSL TKDL+
Sbjct: 1221 PSGNSVSILEL-------STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLS 1273
Query: 1315 GNSEVVAGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQN 1374
N EVVAGTG+QCLPFD++ CGDGG+A +A+L SPRGI VD++G +YFVD TMIRK+D+N
Sbjct: 1274 KNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDEN 1333
Query: 1375 GIISTLLGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITEN 1434
+I+T++GSN LT+ +PLSCDS MD+ QVRLEWPTDLAVNPMDNSLYVL+NN++L+I+EN
Sbjct: 1334 AVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISEN 1393
Query: 1435 HQVSIIAGRPMHCQVPGIDYSL-SKLAIHSALESASAIAISHTGVLYITETDEKKINRLR 1493
+V IIAGRP+HCQVPGID+ L SK+AIHS LESA AI++SH+G+L+I ETDE+K+NR++
Sbjct: 1394 RRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQ 1453
Query: 1494 QVTTNGEICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADL 1553
QVTTNGEI ++AGA +DCDCK D NC+C+SGD YA DA + +PSSLAV+PDGT+Y+ADL
Sbjct: 1454 QVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADL 1513
Query: 1554 GNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSTD 1613
GN+RIR +S+N+ LN N YE ASP +QELY F +G H +T++L+T +Y+YNFTY+++
Sbjct: 1514 GNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNSE 1573
Query: 1614 NDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTY 1673
D+ + +NGNS+ IRRD+ GMP L++P Q+ LT+ +NG LK VS Q L LMTY
Sbjct: 1574 GDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTY 1633
Query: 1674 DGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDD 1733
GNTGLLATKS+E GWTT Y+YD EG LTN T PTG V+S H ++EK ++++ SNR +
Sbjct: 1634 PGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNR-E 1692
Query: 1734 DVTVITNLSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLAGTITPT 1793
+V + TNL++ Y + Q+ +++Y++ +G+LRV +A+GM I SEPH+LAG + PT
Sbjct: 1693 NVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPT 1752
Query: 1794 IGRCNISLPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYD 1853
+G+CNISLP E+ N IEWR RKEQ KG V+ F R+LR H RNLLSID+D RT KIYD
Sbjct: 1753 LGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYD 1812
Query: 1854 DHRKFTLRIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIV 1913
DHRKFTLRI+YDQ GRP LW P S VN++Y +G + +QRG +E+ + D+ G+I+
Sbjct: 1813 DHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKII 1872
Query: 1914 SRMFADGKVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVARHSMSTHTSIGY 1973
SR +ADGK+WSY+YL+KS++LLL SQR+YIFEYD D LL+VTMPS+ RHS+ T S+GY
Sbjct: 1873 SRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLSVTMPSMVRHSLQTMLSVGY 1932
Query: 1974 IRNIYNPPESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGY 2033
RNIY PP+S+ S I DYS DGR+L+T LGTGR+V YKY K ++LSE++YD+T VT Y
Sbjct: 1933 YRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYDTTQVTLTY 1992
Query: 2034 DETTGVLKMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDYTYHDNSFRIAS 2093
+E++GV+K ++L GF CTIRYR+ GPL+ +QI+RFSEEG+VNARFDY+Y N+FR+ S
Sbjct: 1993 EESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSY--NNFRVTS 2050
Query: 2094 IKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDTHGRIKE 2153
++ VI+ETPLP+DLYRY ++SG+ E FGKF VI YD+NQ+ITT VM +K F +G++ E
Sbjct: 2051 MQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIE 2110
Query: 2154 VQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTW 2213
VQYE+ +++ YWMT+QYD++GR++ ++++G AN T+Y Y+YD DGQLQ+V+VND+ W
Sbjct: 2111 VQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQW 2170
Query: 2214 RYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLCQRGSDIFEYNS 2273
RYSYDLNGN++LL+ G S RL PLRYDLRDRITRLG++QYK+D+DG+L QRG+DIFEYNS
Sbjct: 2171 RYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNS 2230
Query: 2274 KGLLTRAYNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSE 2333
GLL +AYNKASGW+VQY YDG+GRR + K++LG HLQ+FY+DL NP R+TH+YNH++SE
Sbjct: 2231 NGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADLTNPIRVTHLYNHTSSE 2290
Query: 2334 ITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSN 2393
ITSLYYDLQGHL AME SSGEEYYVA DNTGTPLAVFS G +IK++ YT YG+IY+D+
Sbjct: 2291 ITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTY 2350
Query: 2394 PDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKEPAPFNLYMFKS 2453
PDFQ++IGFHGGLYD LTKLVH QRDYDV+AGRWT+P++ +WK + P PFNLY F++
Sbjct: 2351 PDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKQLNLLPKPFNLYSFEN 2410
Query: 2454 NNPLSSELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYEL----SESQASE 2509
N P+ D+ Y TD++SWL +FGFQL N++PGFP+ ++ + YEL +++Q +
Sbjct: 2411 NYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWD 2470
Query: 2510 NGQLITGVQQTTERHNQAFMALEGQVITKKLHASIREKAGHW--FATTTPIIGKGIMFAI 2567
G+ I G+Q ++ + F++L+ +T + + + G FA + GKGI FAI
Sbjct: 2471 PGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAI 2530
Query: 2568 KEGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGT 2627
K+G VT + +A+EDSR++A++LNNA+YL+ +H++IEG+DTHYF+K+GS + DLV +G
Sbjct: 2531 KDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGN 2590
Query: 2628 TIGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVL 2687
T GR++LE+GVNVTVSQ T ++NGRTRRF +I+ Q+ L +IRYG T++EEK VL
Sbjct: 2591 TGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYG---TTVEEEKNHVL 2647
Query: 2688 DQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPEL 2747
+ ARQRA+ AW KEQ++ ++G EG R WTEGEKQQLLSTGRVQGY+GY+VL VEQY EL
Sbjct: 2648 EIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLEL 2707
Query: 2748 ADSSSNIQFLRQNEMGKR 2765
+DS++NI F+RQ+E+G+R
Sbjct: 2708 SDSANNIHFMRQSEIGRR 2725
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 235 bits (599), Expect = 5e-61
Identities = 113/292 (38%), Positives = 145/292 (49%), Gaps = 25/292 (8%)
Query: 573 VQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAE 632
V+ CP +C+ G C G C C+PG+ G DC ACP C G G+ G C C +G+ G +
Sbjct: 401 VRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGED 460
Query: 633 CDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSP 692
C V + C G G C G C+C GY G C C C G CV+G C+C+P
Sbjct: 461 CGV---RSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRAC-PGDCRGRGRCVDGRCVCNP 516
Query: 693 GWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGG 752
G+ G +C R CP C GHG L + G+C CD + G DCS C C G C+ G
Sbjct: 517 GFTGEDCGSRR--CPGDCRGHG--LCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDG 572
Query: 753 ACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCT 812
C CE+G++G C R C C +HG C+DG C C EG+ E C+I CP C+G GRC
Sbjct: 573 RCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCE 632
Query: 813 LGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSAC 864
G +C+C G+ GP C M C DC C+Q C
Sbjct: 633 EG----RCLCDPGYTGPTCATRM---CP----------ADCRGRGRCVQGVC 667
Score = 219 bits (558), Expect = 3e-56
Identities = 111/291 (38%), Positives = 141/291 (48%), Gaps = 24/291 (8%)
Query: 573 VQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAE 632
V+ CP +C G G C SG C C+PG+ G DC ACP C G G+ G C C G+ G +
Sbjct: 463 VRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGED 522
Query: 633 CDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSP 692
C ++ C GHG C DG CVC AGY GE C C C G C++G C+C
Sbjct: 523 CG---SRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSC-PGGCRGRGQCLDGRCVCED 578
Query: 693 GWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGG 752
G+ G +C + QCP+ CS HG G+C C ++ DCS+ C +C G C G
Sbjct: 579 GYSGEDCGVR--QCPNDCSQHGVC--QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG 634
Query: 753 ACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHC-----TIDGCPDLCNG 807
C C+ G+TG C R+C C G C G C C G+ GE C CP C
Sbjct: 635 RCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGP 694
Query: 808 NGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC 858
C G QCVC G+RGP C A++T D + G +C D C
Sbjct: 695 RELCRAG----QCVCVEGFRGPDC--AIQTCPGDCR-----GRGECHDGSC 734
Score = 218 bits (556), Expect = 5e-56
Identities = 103/267 (38%), Positives = 128/267 (47%), Gaps = 17/267 (6%)
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
CP +C G G CV G C C PGF G DC CP C G+G G C C +G+ G +C
Sbjct: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCST 556
Query: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
+ C G G C+DG CVC GY GE C C + CS HGVC +G C+C G+
Sbjct: 557 ---RSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWEGYV 612
Query: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
+C + CP C G G + G C CDP + GP C+ +C DC G C+ G C
Sbjct: 613 SEDCSIRT--CPSNCHGRGRC--EEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCL 668
Query: 756 CEEGWTGAACDQR-----VCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGR 810
C G+ G C Q C C C+ G+C C EG+ G C I CP C G G
Sbjct: 669 CHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGE 728
Query: 811 CTLGQNSWQCVCQTGWRGPGCNVAMET 837
C G CVC+ G+ G C + T
Sbjct: 729 CHDGS----CVCKDGYAGEDCGEEVPT 751
Score = 218 bits (555), Expect = 7e-56
Identities = 101/256 (39%), Positives = 128/256 (50%), Gaps = 12/256 (4%)
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
CP +C+ G CV G C CFPG+ G C +CP C G G+ +G C C +G+ G +C
Sbjct: 187 CPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCS- 245
Query: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
+ C G C G CVC GY G+ C C CS G C NG C+C+PG+
Sbjct: 246 --QRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSC-PRGCSQRGRCENGRCVCNPGYT 302
Query: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
G +C + CP CS G G C CDP + G DC C DCG G C+ G C
Sbjct: 303 GEDCGVR--SCPRGCSQRGRC--KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCV 358
Query: 756 CEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQ 815
C G+TG C R C C G C+DG+C C G++G+ C + CP CN GRC G
Sbjct: 359 CWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDG- 417
Query: 816 NSWQCVCQTGWRGPGC 831
+CVC G+ G C
Sbjct: 418 ---RCVCWPGYTGTDC 430
Score = 213 bits (543), Expect = 2e-54
Identities = 102/260 (39%), Positives = 124/260 (47%), Gaps = 12/260 (4%)
Query: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGA 631
S + CPR C G C G C C PG+ G DC +CP CS G+ G C C G+ G
Sbjct: 245 SQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGE 304
Query: 632 ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCS 691
+C V + C G C DG CVC GY GE C C C G CV+G C+C
Sbjct: 305 DCGV---RSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSC-PWDCGEGGRCVDGRCVCW 360
Query: 692 PGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG 751
PG+ G +C CP C G G + G C CD + G DC V C DC G C
Sbjct: 361 PGYTGEDCSTRT--CPRDCRGRGRC--EDGECICDTGYSGDDCGVRSCPGDCNQRGRCED 416
Query: 752 GACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRC 811
G C C G+TG C R C C G C++G C C G++GE C + CP C G GRC
Sbjct: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476
Query: 812 TLGQNSWQCVCQTGWRGPGC 831
G +C+C G+ G C
Sbjct: 477 ESG----RCMCWPGYTGRDC 492
Score = 192 bits (489), Expect = 3e-48
Identities = 109/313 (34%), Positives = 137/313 (43%), Gaps = 38/313 (12%)
Query: 581 HGNGECVSGVCHCFPGFLGADC---------------AKAACPVLCSGNGQYSKGTCQCY 625
HG + C C PG+ G C A +CP C+ G+ +G C C+
Sbjct: 146 HGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCF 205
Query: 626 SGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVN 685
G+ G C P C G G C+ G CVC AG+ G C + C CS G C
Sbjct: 206 PGYTGPSCGWP---SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSC-PRGCSQRGRCEG 261
Query: 686 GECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGT 745
G C+C PG+ G +C + CP CS G + G C C+P + G DC V C C
Sbjct: 262 GRCVCDPGYTGDDCGMR--SCPRGCSQRGRC--ENGRCVCNPGYTGEDCGVRSCPRGCSQ 317
Query: 746 HGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLC 805
G C G C C+ G+TG C R C C E G C DG+C C G+ GE C+ CP C
Sbjct: 318 RGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDC 377
Query: 806 NGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG---DGLVDC---LDPDCC 859
G GRC G +C+C TG+ G C V SC + + G DG C C
Sbjct: 378 RGRGRCEDG----ECICDTGYSGDDCGV---RSCPGDCNQRGRCEDGRCVCWPGYTGTDC 430
Query: 860 LQSACQNSLLCRG 872
AC CRG
Sbjct: 431 GSRACPRD--CRG 441
Score = 152 bits (383), Expect = 6e-36
Identities = 72/201 (35%), Positives = 96/201 (47%), Gaps = 9/201 (4%)
Query: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGA 631
S + CP C G G+C+ G C C G+ G DC CP CS +G G C C+ G+
Sbjct: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSE 614
Query: 632 ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCS 691
+C + + +C G G C +G C+C GY G C C C G CV G CLC
Sbjct: 615 DCSI---RTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC-PADCRGRGRCVQGVCLCH 670
Query: 692 PGWGGLNC---ELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGV 748
G+GG +C E CP C L G C C + GPDC+++ C DC G
Sbjct: 671 VGYGGEDCGQEEPPASACPGGCGPR--ELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGE 728
Query: 749 CIGGACRCEEGWTGAACDQRV 769
C G+C C++G+ G C + V
Sbjct: 729 CHDGSCVCKDGYAGEDCGEEV 749
Score = 99.0 bits (245), Expect = 6e-20
Identities = 50/139 (35%), Positives = 63/139 (45%), Gaps = 19/139 (13%)
Query: 710 CSGHGTYLPDTGLCSCDPNWMGPDCS----VEV-----------CSVDCGTHGVCIGGAC 754
CS HG + CSC+P W GP CS E+ C DC G C+ G C
Sbjct: 143 CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202
Query: 755 RCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLG 814
C G+TG +C C C G C G C CR G++G C+ CP C+ GRC G
Sbjct: 203 VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 262
Query: 815 QNSWQCVCQTGWRGPGCNV 833
+CVC G+ G C +
Sbjct: 263 ----RCVCDPGYTGDDCGM 277
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 233 bits (595), Expect = 2e-60
Identities = 116/308 (37%), Positives = 163/308 (52%), Gaps = 30/308 (9%)
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSG-NGQYSKGTCQCYSGWKGAECD 634
CP +C+ G+CV+GVC CF G+ GADC++ CPV CS +G G C C+ G+ G +C+
Sbjct: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
Query: 635 VPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGW 694
P+ C++ +C G C++ CVC G+ GE C E+ C + C G C+NG C C G+
Sbjct: 281 KPL--CLN-NCYNRGRCVENECVCDEGFTGEDCSELICPND-CFDRGRCINGTCYCEEGF 336
Query: 695 GGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGAC 754
G +C + CP C G + G C CD + G DCS + C DC G C+ G C
Sbjct: 337 TGEDC--GKPTCPHACHTQGRC--EEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRC 392
Query: 755 RCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLG 814
C++G+TGA C + C C HG C +G+C C EG+ GE C+ CP+ C+ GRC G
Sbjct: 393 ECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEG 452
Query: 815 QNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG----------DGLV--DCLDPDCCLQS 862
+CVC+ G++G C+ + SC ++ G DG DC D C
Sbjct: 453 ----KCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQC--PR 503
Query: 863 ACQNSLLC 870
C N LC
Sbjct: 504 DCSNRGLC 511
Score = 231 bits (589), Expect = 7e-60
Identities = 107/283 (37%), Positives = 145/283 (51%), Gaps = 19/283 (6%)
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
CP +C G C++G C+C GF G DC K CP C G+ +G C C G+ G +C
Sbjct: 315 CPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSE 374
Query: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
+C C G C+DG C C G+ G C E+ C + CS HG CVNG+C+C G+
Sbjct: 375 --KRC-PADCHNRGRCVDGRCECDDGFTGADCGELKCPNG-CSGHGRCVNGQCVCDEGYT 430
Query: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
G +C ++++CP+ C G + G C C+ + G DCS C DC HG C+ G C
Sbjct: 431 GEDC--SQLRCPNDCHSRGRCVE--GKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCV 486
Query: 756 CEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQ 815
C++G+TG C R C C G C DG+C C +G+ G C CP+ C+G GRC G
Sbjct: 487 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNG- 545
Query: 816 NSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC 858
QCVC G+ G C E C + +G C+D C
Sbjct: 546 ---QCVCHEGFMGKDCK---EQRCPSDCHGQG----RCVDGQC 578
Score = 223 bits (569), Expect = 2e-57
Identities = 103/261 (39%), Positives = 136/261 (52%), Gaps = 12/261 (4%)
Query: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGA 631
S + CP +CH G CV G C C GF GADC + CP CSG+G+ G C C G+ G
Sbjct: 373 SEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGE 432
Query: 632 ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCS 691
+C +C + C G C++G CVC G+KG C ++ C + C HG CVNG C+C
Sbjct: 433 DCS--QLRCPN-DCHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCD 488
Query: 692 PGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG 751
G+ G +C QCP CS G + G C C+ + GPDC+ C DC G C+
Sbjct: 489 DGYTGEDCRDR--QCPRDCSNRGLCVD--GQCVCEDGFTGPDCAELSCPNDCHGQGRCVN 544
Query: 752 GACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRC 811
G C C EG+ G C ++ C C G C DG+C C EG+ G C CP CN G+C
Sbjct: 545 GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604
Query: 812 TLGQNSWQCVCQTGWRGPGCN 832
G +C+C G+ G C+
Sbjct: 605 VSG----RCICNEGYSGEDCS 621
Score = 162 bits (411), Expect = 3e-39
Identities = 75/192 (39%), Positives = 97/192 (50%), Gaps = 8/192 (4%)
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
CP +CH G CV G C C GF G DC+ +CP C +G+ G C C G+ G +C
Sbjct: 439 CPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRD 498
Query: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
QC C G C+DG CVC G+ G C E+ C + C G CVNG+C+C G+
Sbjct: 499 --RQC-PRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND-CHGQGRCVNGQCVCHEGFM 554
Query: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
G +C+ R CP C G G + G C C + G DC C DC G C+ G C
Sbjct: 555 GKDCKEQR--CPSDCHGQGRCVD--GQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCI 610
Query: 756 CEEGWTGAACDQ 767
C EG++G C +
Sbjct: 611 CNEGYSGEDCSE 622
Score = 130 bits (328), Expect = 1e-29
Identities = 70/193 (36%), Positives = 88/193 (45%), Gaps = 24/193 (12%)
Query: 675 PTCSSHG-VCVNG-ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGP 732
P CS G G C+C PGW G NC + +CP C G + G C CD + G
Sbjct: 159 PFCSGRGNFSTEGCGCVCEPGWKGPNC--SEPECPGNCHLRGRCI--DGQCICDDGFTGE 214
Query: 733 DCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCI-EHGTCKDGKCECREGW 791
DCS C DC G C+ G C C EG+ GA C + +C C EHGTC DG C C +G+
Sbjct: 215 DCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGF 274
Query: 792 NGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLV 851
G+ C C + C GRC +CVC G+ G C+ E C +
Sbjct: 275 AGDDCNKPLCLNNCYNRGRCVEN----ECVCDEGFTGEDCS---ELICPN---------- 317
Query: 852 DCLDPDCCLQSAC 864
DC D C+ C
Sbjct: 318 DCFDRGRCINGTC 330
Score = 113 bits (283), Expect = 2e-24
Identities = 65/195 (33%), Positives = 89/195 (45%), Gaps = 23/195 (11%)
Query: 690 CSPGWGG-LNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGV 748
C+ G G L R+ CSG G + + C C+P W GP+CS C +C G
Sbjct: 140 CTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGR 199
Query: 749 CIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCN-G 807
CI G C C++G+TG C Q C C + G C +G C C EG+ G C+ + CP C+
Sbjct: 200 CIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEE 259
Query: 808 NGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC--------- 858
+G C G CVC G+ G CN + C +N N G C++ +C
Sbjct: 260 HGTCVDG----LCVCHDGFAGDDCNKPL---CLNNCYNRG----RCVENECVCDEGFTGE 308
Query: 859 -CLQSACQNSLLCRG 872
C + C N RG
Sbjct: 309 DCSELICPNDCFDRG 323
Score = 102 bits (253), Expect = 7e-21
Identities = 43/96 (44%), Positives = 55/96 (57%), Gaps = 5/96 (5%)
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
CP +CHG G CV+G C C GF+G DC + CP C G G+ G C C+ G+ G +C
Sbjct: 532 CPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG- 590
Query: 636 PMNQCIDPS-CGGHGSCIDGNCVCSAGYKGEHCEEV 670
+ C PS C G C+ G C+C+ GY GE C EV
Sbjct: 591 -QHSC--PSDCNNLGQCVSGRCICNEGYSGEDCSEV 623
Score = 41.6 bits (96), Expect = 0.011
Identities = 15/33 (45%), Positives = 22/33 (66%)
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACP 608
CP +C+ G+CVSG C C G+ G DC++ + P
Sbjct: 594 CPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 156 bits (395), Expect = 2e-37
Identities = 87/265 (32%), Positives = 118/265 (44%), Gaps = 18/265 (6%)
Query: 576 CPRNCHGNGECVS-GVCHCFPGFLGADCAKAACPVLCSGNGQYSK-GTCQCYSGWKGAEC 633
C C + ECV+ +C C PG++G++C A C C +G+ K CQC G GA C
Sbjct: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 1357
Query: 634 DVPMNQCIDPSCGGHGSCIDGN-CVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGE-CLCS 691
D + +P C G+C+ GN C C G+ G CE + C + C + G C+ + C C
Sbjct: 1358 D---EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVC-NRHCENGGQCLTPDICQCK 1413
Query: 692 PGWGGLNCELARVQCPDQC-SGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCI 750
PGW G C A C C +G P+T C C + G C C C G C+
Sbjct: 1414 PGWYGPTCSTA--LCDPVCLNGGSCNKPNT--CLCPNGFFGEHCQNAFCHPPCKNGGHCM 1469
Query: 751 -GGACRCEEGWTGAACDQRVCHPRCIEHGTC-KDGKCECREGWNGEHCTIDGCPDLCNGN 808
C C EG+TG + +C P C+ G C C C GW+G+ C C C
Sbjct: 1470 RNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNG 1529
Query: 809 GRCTLGQNSWQCVCQTGWRGPGCNV 833
G C C C + W G C +
Sbjct: 1530 GECIAPS---ICHCPSSWEGVRCQI 1551
Score = 137 bits (346), Expect = 1e-31
Identities = 77/230 (33%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Query: 574 QDCPRNCHGNGECVSG-VCHCFPGFLGADCAKAACPVLCSGNGQ-YSKGTCQCYSGWKGA 631
+ C C G C++G +C C GF+G C C C GQ + CQC GW G
Sbjct: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
Query: 632 ECDVPMNQCIDPSCGGHGSCIDGN-CVCSAGYKGEHCEEVDCLDPTCSSHGVCV-NGECL 689
C + DP C GSC N C+C G+ GEHC+ C P C + G C+ N C+
Sbjct: 1420 TCSTAL---CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNNVCV 1475
Query: 690 CSPGWGGLNCELARVQCPDQCSGHGTYL-PDTGLCSCDPNWMGPDCSVEVCSVDCGTHGV 748
C G+ G + + C C G + P T CSC W G C+ +C C G
Sbjct: 1476 CREGYTGRRFQ--KSICDPTCMNGGKCVGPST--CSCPSGWSGKRCNTPICLQKCKNGGE 1531
Query: 749 CIG-GACRCEEGWTGAACDQRVCHPRCIEHGTC-KDGKCECREGWNGEHC 796
CI C C W G C +C+P+C+ G C C CR ++G C
Sbjct: 1532 CIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
Score = 104 bits (260), Expect = 1e-21
Identities = 96/356 (26%), Positives = 132/356 (37%), Gaps = 57/356 (16%)
Query: 572 SVQDCPRNCHGNGECVSG----------VCHCFPGFLGADCAKAACPVLCSGNGQYSKGT 621
+V+ C +C G CVS +C C PGF G+ C V SG G
Sbjct: 1177 TVKSC--DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGS-----LCEVDISGCQSNPCGL 1229
Query: 622 CQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHG 681
SG+ CD P ++ + V + K + EE D H
Sbjct: 1230 GSYISGFHSYSCDCPPELKVETQFVNQFTT--QTVVLTRSDKSVNKEEDDKNAQGRKRHV 1287
Query: 682 VCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSV 741
+G A C C G +C C P ++G +C +C
Sbjct: 1288 KPTSGN--------------AFTICKYPC-GKSRECVAPNICKCKPGYIGSNCQTALCDP 1332
Query: 742 DCGTHGVCI-GGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGK-CECREGWNGEHCTID 799
DC HG CI C+C G GA CD+ C+P C GTC G C C G+ G C
Sbjct: 1333 DCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETM 1392
Query: 800 GCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAM-ETSCAD----NKDNEGDGLVDCL 854
C C G+C C C+ GW GP C+ A+ + C + NK N CL
Sbjct: 1393 VCNRHCENGGQCLTPD---ICQCKPGWYGPTCSTALCDPVCLNGGSCNKPN------TCL 1443
Query: 855 DPDCCLQSACQNSLL---CRGS----RDPLDIIQQGQTDWPAVKSFYDRIKLLAGK 903
P+ CQN+ C+ R+ + + ++G T KS D + GK
Sbjct: 1444 CPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGK 1499
Score = 82.0 bits (201), Expect = 7e-15
Identities = 63/249 (25%), Positives = 84/249 (33%), Gaps = 71/249 (28%)
Query: 669 EVDCLDPTCSSHGVCVNGE----------CLCSPGWGGLNCELARVQCPDQCSGHGTYLP 718
EV C + G CV+ C+C PG+ G CE+ C G G+Y+
Sbjct: 1175 EVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYIS 1234
Query: 719 DTGLCSCDPNWMGPDCSVE----------------------------------------- 737
SCD P+ VE
Sbjct: 1235 GFHSYSCD---CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTS 1291
Query: 738 -----VCSVDCGTHGVCIG-GACRCEEGWTGAACDQRVCHPRCIEHGTC-KDGKCECREG 790
+C CG C+ C+C+ G+ G+ C +C P C HG C K C+C G
Sbjct: 1292 GNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPG 1351
Query: 791 WNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGL 850
G C + C C G C G C C G+ GP C + C + +N G
Sbjct: 1352 HGGATCDEEHCNPPCQHGGTCLAGN---LCTCPYGFVGPRCETMV---CNRHCENGG--- 1402
Query: 851 VDCLDPDCC 859
CL PD C
Sbjct: 1403 -QCLTPDIC 1410
Score = 39.3 bits (90), Expect = 0.054
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCA 603
SV CP C GNG+C+ C C P F DC+
Sbjct: 886 SVLKCPNLCSGNGQCMEWGCACSPSFSSYDCS 917
Score = 34.3 bits (77), Expect = 1.8
Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 11/73 (15%)
Query: 762 GAACDQRVCHPRCIEHGTCKDGKCECREGWNG--EHCTIDGCPDLCNGNGRCTLGQNSWQ 819
G A + C R +E +GK E + ++ CP+LC+GNG+C W
Sbjct: 854 GVALLENECEKRIVE-----EGKYNTEEYGTSIEDILSVLKCPNLCSGNGQCM----EWG 904
Query: 820 CVCQTGWRGPGCN 832
C C + C+
Sbjct: 905 CACSPSFSSYDCS 917
Score = 32.0 bits (71), Expect = 8.7
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 607 CPVLCSGNGQYSKGTCQCYSGWKGAEC 633
CP LCSGNGQ + C C + +C
Sbjct: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC 916
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 152 bits (383), Expect = 6e-36
Identities = 111/345 (32%), Positives = 147/345 (42%), Gaps = 61/345 (17%)
Query: 580 CHGNGECVSGVCH-----------------CFPGFLGA-------DCAKAACPVLCSGNG 615
CH + CVS CH C PGF G +C+ A P G
Sbjct: 349 CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC 408
Query: 616 QYSKGT--CQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE- 668
++G+ CQC G+ G C+ +N+C+ C +C+D C+C AG+ G +CE
Sbjct: 409 VNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV 468
Query: 669 EVD-CLDPTCSSHGVC---VNG-ECLCSPGWGGLNCELARVQCPDQCSGHGTYL---PDT 720
++D C C + GVC VNG C C G+ G C+L +C +G PD
Sbjct: 469 DIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDG 528
Query: 721 GLCSCDPNWMGPDC--SVEVCSVDCGTHGVCIGG----ACRCEEGWTGAACDQRVCHPR- 773
C C + G C +V+ CS D HG C+ G +C C G+TG C+ +V R
Sbjct: 529 YECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRS 588
Query: 774 --CIEHGTCKD----GKCECREGWNGEHC--TIDGCPDLCNGNGRCTLGQNSWQCVCQTG 825
C G C D C C G G +C ID C G C G N + CVCQ G
Sbjct: 589 QPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPG 648
Query: 826 WRGPGCNVAMETSCADNKDNEGDGLVD------CLDPDCCLQSAC 864
+ GP CNV + CA + EG VD CL P L C
Sbjct: 649 FTGPLCNVEI-NECASSPCGEGGSCVDGENGFRCLCPPGSLPPLC 692
Score = 142 bits (358), Expect = 5e-33
Identities = 112/386 (29%), Positives = 148/386 (38%), Gaps = 85/386 (22%)
Query: 573 VQDC-PRNCHGNGECVSGV----CHCFPGFLGA-------DCAKAACPVLCSGNGQYSKG 620
V +C + C G+C+ V C C G G DCA C +G ++
Sbjct: 583 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDG-INRY 641
Query: 621 TCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHC--EEVDCLD 674
C C G+ G C+V +N+C CG GSC+DG C+C G C C
Sbjct: 642 DCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH 701
Query: 675 PTCSSHGVCVNG----ECLCSPGWGGLNC--ELARVQCPDQ-CSGHGTYLPD-------- 719
C SHG+C + C+C PGW G C LAR C Q C GT D
Sbjct: 702 EPC-SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTC 760
Query: 720 --------------------------------TGLCSCDPNWMGPDC--SVEVCS--VDC 743
+CSC W GP C V+ C+ C
Sbjct: 761 PPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPC 820
Query: 744 GTHGVCIGGA----CRCEEGWTGAACDQRV--CHPR-CIEHGTCKDG----KCECREGWN 792
G HG+C A C C G+TG +CDQ + C P C+ G+C+DG C C G+
Sbjct: 821 GPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA 880
Query: 793 GEHCT--IDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGL 850
G C +D C G G CT S+ C C G+ G C + C+ + G
Sbjct: 881 GPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDL-PDCSPSSCFNGGTC 939
Query: 851 VDCLDPDCCLQSACQNSLLCRGSRDP 876
VD ++ CL C+ DP
Sbjct: 940 VDGVNSFSCLCRPGYTGAHCQHEADP 965
Score = 142 bits (357), Expect = 6e-33
Identities = 108/342 (31%), Positives = 138/342 (40%), Gaps = 63/342 (18%)
Query: 572 SVQDC-PRNCHGNGECVSGV----CHCFPGFLGADCAKAACPVL---CSGNGQ----YSK 619
+V DC P CH +G CV G+ C C PG+ G C C G+ K
Sbjct: 545 NVDDCSPDPCH-HGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDK 603
Query: 620 GTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHC--EEVDCL 673
C+C SG G C+V ++ C C G C DG +CVC G+ G C E +C
Sbjct: 604 YLCRCPSGTTGVNCEVNIDDCASNPCT-FGVCRDGINRYDCVCQPGFTGPLCNVEINECA 662
Query: 674 DPTCSSHGVCVNGE----CLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTG--LCSCDP 727
C G CV+GE CLC PG C C + HG G C C+P
Sbjct: 663 SSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEP 722
Query: 728 NWMGPDCSVEVC-----SVDCGTHGVC----IGGACRCEEGWTGAACDQ-RVCHPRCIEH 777
W GP CS + S C G C +G C C G G C+ C P EH
Sbjct: 723 GWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEH 782
Query: 778 G-TCKDGK-----CECREGWNGEHCT--IDGC--PDLCNGNGRCTLGQNSWQCVCQTGWR 827
G C+ C C +GW G C +D C P C +G CT S+ C C G+
Sbjct: 783 GGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT 842
Query: 828 GPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQ-SACQNSL 868
GP C+ + DC DP+ CL +CQ+ +
Sbjct: 843 GPSCD---------------QDINDC-DPNPCLNGGSCQDGV 868
Score = 133 bits (334), Expect = 3e-30
Identities = 101/341 (29%), Positives = 131/341 (38%), Gaps = 57/341 (16%)
Query: 573 VQDC-PRNCHGNGECVSGV----CHCFPGFLGADCAKAACPVLCSGNG------QYSKGT 621
+ DC P C G C GV C C PGF G CA+ L + G + T
Sbjct: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFT 909
Query: 622 CQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE-EVD-CLDP 675
C C G+ G C+ + C SC G+C+DG +C+C GY G HC+ E D CL
Sbjct: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
Query: 676 TCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQ-CSGHGTYLPDTGLCSCDPNWM 730
C GVC C C + G C+ C Q C G + C C P W
Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWS 1029
Query: 731 GPDCSVEVCSVD-------------CGTHGVCI----GGACRCEEGWTGAACDQRV--CH 771
G C + C G C+ C C EG TG+ C+Q V C
Sbjct: 1030 GRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCL 1089
Query: 772 PRCIEH-GTCK----DGKCECREGWNGEHC--TIDGCPDL-CNGNGRCTLGQNSWQCVCQ 823
+ +H GTC+ CEC G+NG++C +D C C G C + C C
Sbjct: 1090 AQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCP 1149
Query: 824 TGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSAC 864
G G C + N+D+ G G P C C
Sbjct: 1150 PGTLGVLCEI--------NEDDCGPGPPLDSGPRCLHNGTC 1182
Score = 131 bits (330), Expect = 8e-30
Identities = 104/361 (28%), Positives = 136/361 (37%), Gaps = 70/361 (19%)
Query: 580 CHGNGECVSGV----CHCFPGFLGADCA--KAACPVLCSGNGQYSKG-----TCQCYSGW 628
C G C S C C PG G C P C G+ C C GW
Sbjct: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGW 802
Query: 629 KGAECDVPMNQCIDPS-CGGHGSCID----GNCVCSAGYKGEHCEEV--DCLDPTCSSHG 681
+G C +++C P+ CG HG C + +C C GY G C++ DC C + G
Sbjct: 803 QGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGG 862
Query: 682 VCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTG--LCSCDPNWMGPDCS 735
C +G C C PG+ G C +C G GT C+C P + G C
Sbjct: 863 SCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCE 922
Query: 736 VEV--CSVD-CGTHGVCIGG----ACRCEEGWTGAACDQRV--CHPR-CIEHGTCKDG-- 783
++ CS C G C+ G +C C G+TGA C C R C+ G C
Sbjct: 923 QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP 982
Query: 784 --KCECREGWNGEHCT--IDGCP-DLCNGNGRCTLGQNSWQCVCQTGWRGPGCN------ 832
+C C E + G C +D C C GRC Q C+C GW G C+
Sbjct: 983 GFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCV--QTGAYCLCPPGWSGRLCDIRSLPC 1040
Query: 833 --------VAMETSC-ADNKDNEGDGLVDCLDP------------DCCLQSACQNSLLCR 871
V +E C A + + D C+ P D CL CQ+ CR
Sbjct: 1041 REAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCR 1100
Query: 872 G 872
G
Sbjct: 1101 G 1101
Score = 128 bits (321), Expect = 9e-29
Identities = 89/309 (28%), Positives = 129/309 (41%), Gaps = 40/309 (12%)
Query: 580 CHGNGECVSGV----CHCFPGFLGADCAKAA--CPVLCSGNGQYSKG-----TCQCYSGW 628
C C+ + C C GF G C C NG K +C C SG+
Sbjct: 440 CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF 499
Query: 629 KGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEE-VDCLDPTCSSHGVC 683
G+ C + +++C C C+D C C+ G++G C+ VD P HG C
Sbjct: 500 SGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRC 559
Query: 684 VNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTY---LPDTGLCSCDPNWMGPDCSV 736
V+G C C+PG+ G CE +C Q HG L D LC C G +C V
Sbjct: 560 VDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEV 619
Query: 737 EV--CSVDCGTHGVCIGGA----CRCEEGWTGAACDQRV---CHPRCIEHGTCKDG---- 783
+ C+ + T GVC G C C+ G+TG C+ + C E G+C DG
Sbjct: 620 NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGF 679
Query: 784 KCECREGWNGEHCTIDGCP---DLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCA 840
+C C G C P + C+ +G C ++CVC+ GW GP C+ ++
Sbjct: 680 RCLCPPGSLPPLCLPPSHPCAHEPCS-HGICYDAPGGFRCVCEPGWSGPRCSQSLARDAC 738
Query: 841 DNKDNEGDG 849
+++ G
Sbjct: 739 ESQPCRAGG 747
Score = 114 bits (285), Expect = 1e-24
Identities = 99/358 (27%), Positives = 138/358 (38%), Gaps = 70/358 (19%)
Query: 580 CHGNGECV----SGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQ----------CY 625
C G C+ S C C G+ G C A P C+ + + GTC+ C
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP--CAPSPCRNGGTCRQSGDLTYDCACL 225
Query: 626 SGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHC-EEVD-C-LDP-TC 677
G++G C+V ++ C C G+C+DG NC C + G+ C E+VD C L P C
Sbjct: 226 PGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNAC 285
Query: 678 SSHGVCVN----GECLCSPGWGGLNCELARVQCPDQCSGHGTYLPD---TGLCSCDPNWM 730
+ G C N C+C GW G +C C HG D + C+C
Sbjct: 286 HNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKT 345
Query: 731 GPDCSVEVCSVD--------CGTHGVCIGGACRCEEGWTGAACDQRV------CHPRCIE 776
G C ++ V C T+ V C C G+TG ACDQ V +P C
Sbjct: 346 GLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANP-CEH 404
Query: 777 HGTCKDGK----CECREGWNGEHCTIDGCPDL---CNGNGRCTLGQNSWQCVCQTGWRGP 829
G C + + C+C G+ G C D L C C + C+C G+ G
Sbjct: 405 LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGT 464
Query: 830 GCNVAME----TSCADN---KDNEGDGLVDC----------LDPDCCLQSACQNSLLC 870
C V ++ + C + KD C LD D C + C+N C
Sbjct: 465 YCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKC 522
Score = 112 bits (281), Expect = 4e-24
Identities = 97/325 (29%), Positives = 131/325 (40%), Gaps = 58/325 (17%)
Query: 580 CHGNGECVS-----GVCHCFPGFLGADCA-KAACPV-LCSGNGQYSKG--------TCQC 624
C G C C C PG++G C + C C+G G +C+C
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
Query: 625 YSGWKGAECDVPMNQCIDPSCGGHGSCIDGN-----CVCSAGYKGEHC-EEVD-C-LDPT 676
G++G +C +P + C+ C C G C C GY+G C +VD C +
Sbjct: 109 PRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167
Query: 677 CSSHGVCVNG----ECLCSPGWGGLNCELARVQC-PDQCSGHGTYLPDTGL---CSCDPN 728
C G C+N C C G+ G CE V C P C GT L C+C P
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPG 227
Query: 729 WMGPDCSVEVCSVDCGTH-----GVCIGGA----CRCEEGWTGAACDQRV--CHPR---C 774
+ G +C V V DC H G C+ G C+C WTG C + V C + C
Sbjct: 228 FEGQNCEVNV--DDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNAC 285
Query: 775 IEHGTCKD----GKCECREGWNGEHCT--IDGCPD-LCNGNGRCTLGQNSWQCVCQTGWR 827
GTC + C C GW GE C+ ID C +C C S+ C C G
Sbjct: 286 HNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKT 345
Query: 828 GPGCNVAMETSCADNKDNEGDGLVD 852
G C+ ++ +C N +E D + D
Sbjct: 346 GLLCH--LDDACVSNPCHE-DAICD 367
Score = 99.0 bits (245), Expect = 6e-20
Identities = 98/364 (26%), Positives = 128/364 (35%), Gaps = 98/364 (26%)
Query: 571 DSVQDCPRN-CHGNGECVSGV----CHCFPGFLGADCA--KAAC---PVLCSGNGQYSKG 620
D V +C C G C+ V C C PG LG C + C P L SG G
Sbjct: 1121 DDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNG 1180
Query: 621 TC---------QCYSGWKGAECDVPMNQCIDPSCGGHGS--CIDG-----NCVCSAGYKG 664
TC C G+ G C+ +N+C +C + C+ C+C AG+ G
Sbjct: 1181 TCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSG 1240
Query: 665 EHCEEVDCLDPTCSSHGVCVNGECLCSPGWGG---LNCELAR----------------VQ 705
C+ V L P C S G+C SPG GG C A+ +Q
Sbjct: 1241 PRCQTV--LSP-CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQ 1297
Query: 706 CPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCI------GGACR---- 755
CP T P C+C P GP C S ++ C GG+CR
Sbjct: 1298 CPVGVPCQQT--PRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPL 1355
Query: 756 -------CEEGWTGAACDQRVCHPRCIEHGTCKDGKCECRE--------------GWNGE 794
C +GWTG C+ P E C C+ + GW+G
Sbjct: 1356 APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGG 1415
Query: 795 HCTID-----------GCPDLCNGNGRCTLGQNSWQCV-----CQTGWRGPGCNVAMETS 838
C++ C L N N RC +S C+ C G R CN E
Sbjct: 1416 DCSLSVGDPWRQCEALQCWRLFN-NSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKY 1474
Query: 839 CADN 842
CAD+
Sbjct: 1475 CADH 1478
Score = 83.6 bits (205), Expect = 3e-15
Identities = 82/298 (27%), Positives = 105/298 (35%), Gaps = 78/298 (26%)
Query: 672 CLDPT-CSSHGVCVN-----GECLCSPGWGGLNCEL-----------------------A 702
CLD + C++ G C CLC PGW G C+L A
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTA 102
Query: 703 RVQC-------------PDQC----SGHGTYL---PD-TGLCSCDPNWMGPDC--SVEVC 739
R C PD C HG PD LCSC P + G C V+ C
Sbjct: 103 RFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDEC 162
Query: 740 SV--DCGTHGVCIGG----ACRCEEGWTGAACDQRV--CHPR-CIEHGTCKDG-----KC 785
V C G C+ C+C G+TG C+ C P C GTC+ C
Sbjct: 163 RVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDC 222
Query: 786 ECREGWNGEHC--TIDGCP-DLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAM-ETSCAD 841
C G+ G++C +D CP C G C G N++ C C W G C + E
Sbjct: 223 ACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQP 282
Query: 842 NKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLD-----IIQQGQTDWPAVKSFY 894
N + G + L C+ C N +D + G T V SFY
Sbjct: 283 NACHNGGTCFNTLGGHSCV---CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFY 337
Score = 46.2 bits (108), Expect = 4e-04
Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 33/120 (27%)
Query: 762 GAACDQRVCHPRCIEHGTC-----KDGKCECREGWNGEHCTI-DGCPD-LCNGNGRC--- 811
GAA + C G C ++ C C GW GE C + D C C G G C
Sbjct: 37 GAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSS 96
Query: 812 -TLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
G + C C G+RGP C++ PD CL S C + C
Sbjct: 97 VVAGTARFSCRCPRGFRGPDCSL----------------------PDPCLSSPCAHGARC 134
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 151 bits (382), Expect = 8e-36
Identities = 108/397 (27%), Positives = 159/397 (40%), Gaps = 94/397 (23%)
Query: 573 VQDCPRN-CHGNGECVSGV----CHCFPGFLGADCAK-----AACPVLCSGN--GQYSKG 620
V +C N C + C+ + C C PG+ G C A+ P L +G + ++
Sbjct: 453 VNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEF 512
Query: 621 TCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE-EVDCLDP 675
C+C +G+ G C +++C C C+DG CVC+ GY G HCE ++D DP
Sbjct: 513 QCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP 572
Query: 676 TCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTG---LCSCDPN 728
+G C +G CLC PG+ G +CE +C Q HG D LC C
Sbjct: 573 DPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKG 632
Query: 729 WMGPDCSVEV--CSVDCGTHGVCI----GGACRCEEGWTGAACDQRV-------CH---- 771
GP+C + + C+ G C+ G C CE G+TG+ C+ + CH
Sbjct: 633 TTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGT 692
Query: 772 ------------------PRCIE-----------HGTCKDG----KCECREGWNGEHCTI 798
P C+ HG C+D KC+C GW+G +C I
Sbjct: 693 CEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDI 752
Query: 799 DG--CP-DLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLD 855
+ C + C G C + + C C+ G+ GP C + ++ N+G + D
Sbjct: 753 NNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAG 812
Query: 856 PDC-----------------CLQSACQNSLLCRGSRD 875
C C S C+N CR S D
Sbjct: 813 YKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSED 849
Score = 141 bits (356), Expect = 8e-33
Identities = 93/322 (28%), Positives = 137/322 (42%), Gaps = 49/322 (15%)
Query: 572 SVQDCPRN-CHGNGECVSGV----CHCFPGFLGADCAKAACPVL---------CSGNGQY 617
++ +C N C G C+ V C+C + GA C P C + Y
Sbjct: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDY 850
Query: 618 SKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHCEE--VD 671
+C C +GW+G C+V +N+C+ C SC + + C C AGY G +CE D
Sbjct: 851 ESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDD 910
Query: 672 CLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC---PDQCSGHGTYLPDTGLCS 724
C C + G C +G C C PG+ G CE +C P + + T D+ C+
Sbjct: 911 CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCT 970
Query: 725 CDPNWMGPDC---SVEVCSVDCGTHGVCIGG----ACRCEEGWTGAAC--DQRVCHPR-C 774
C + G C + + C G C+ G C C G+TG+ C D C + C
Sbjct: 971 CPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPC 1030
Query: 775 IEHGTCKDG----KCECREGWNGEHCT-----IDGCPDLCNGNGRCTLGQNSWQCVCQTG 825
+ GTC+DG +C C +G+ G +C D P C G+C ++C C +G
Sbjct: 1031 LHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSP--CKNGGKCWQTHTQYRCECPSG 1088
Query: 826 WRGPGCNVAMETSCADNKDNEG 847
W G C+V SC +G
Sbjct: 1089 WTGLYCDVP-SVSCEVAAQRQG 1109
Score = 135 bits (341), Expect = 4e-31
Identities = 95/350 (27%), Positives = 147/350 (42%), Gaps = 61/350 (17%)
Query: 579 NCHGNGECVSGVCHCFPGFLGA-------DCAKAACPVLCSGNGQYSKGT--CQCYSGWK 629
NC N +C C G+ G +C+ A P +G + G+ CQC G+
Sbjct: 386 NCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT 445
Query: 630 GAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE--EVDCLDPTCSSHGVC 683
G C++ +N+C+ C +C+D C+C GY+G HCE +C C +G C
Sbjct: 446 GPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC 505
Query: 684 VNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYL---PDTGLCSCDPNWMGPDCSV 736
++ +C C G+ G C+ +C +G P+T C C + G C V
Sbjct: 506 LDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV 565
Query: 737 EV--CSVDCGTHGVCIGG----ACRCEEGWTGAACDQRV--CHPR-CIEHGTCKDGK--- 784
++ C D +G C G C C G+TG C+ + C + C GTC+D
Sbjct: 566 DIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAY 625
Query: 785 -CECREGWNGEHCTI--DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCAD 841
C C +G G +C I D C +G C + ++C C+ G+ G CN+ ++ CA
Sbjct: 626 LCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINID-ECAG 684
Query: 842 NKDNEGDGLVDCL------------DPDC-----------CLQSACQNSL 868
N + G D + DP C C+ AC++SL
Sbjct: 685 NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSL 734
Score = 128 bits (322), Expect = 7e-29
Identities = 105/386 (27%), Positives = 149/386 (38%), Gaps = 89/386 (23%)
Query: 572 SVQDCPRN-CHGNGECVSG----VCHCFPGFLGA-------DCAKAACPVLCSGN--GQY 617
++ +C C G C +C C G G DCA + C SG +
Sbjct: 603 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD---SGTCLDKI 659
Query: 618 SKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHC--EEVD 671
C C G+ G+ C++ +++C C G+C DG C C GY C E +
Sbjct: 660 DGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNE 719
Query: 672 CLDPTCSSHGVC---VNG-ECLCSPGWGGLNCELARVQCPDQ-CSGHGTYLPDTG--LCS 724
C C HG C +NG +C C PGW G NC++ +C C GT T +C+
Sbjct: 720 CNSNPCV-HGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCT 778
Query: 725 CDPNWMGPDCSV---EVCSVDCGTHGVCI------------------------------- 750
C + GP+C E S C G CI
Sbjct: 779 CREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC 838
Query: 751 --GGACR-----------CEEGWTGAACDQRV--CHPRCIEHG-TCKDG----KCECREG 790
GG CR C GW G C+ + C HG +C++ +C C+ G
Sbjct: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAG 898
Query: 791 WNGEHCT--IDGC-PDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG 847
++G +C ID C P+ C+ G CT G N+ C C G+RG C + CA + G
Sbjct: 899 YSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDIN-ECASDPCRNG 957
Query: 848 DGLVDCLDPDCCLQSACQNSLLCRGS 873
DC+D C A + + C +
Sbjct: 958 ANCTDCVDSYTCTCPAGFSGIHCENN 983
Score = 127 bits (319), Expect = 2e-28
Identities = 93/348 (26%), Positives = 134/348 (38%), Gaps = 54/348 (15%)
Query: 572 SVQDCPRN-CHGNGECVSGV----CHCFPGFLGADCAKAACPVLCSGN--------GQYS 618
++ +C N CH G C G+ C C G+ C C+ N +
Sbjct: 678 NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNE--CNSNPCVHGACRDSLN 735
Query: 619 KGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHCEE--VDC 672
C C GW G CD+ N+C C G+C D C C G+ G +C+ +C
Sbjct: 736 GYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINEC 795
Query: 673 LDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC-PDQCSGHGTYLP----DTGLC 723
C + G C++ +C C + G CE+ C P C G ++ C
Sbjct: 796 ASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSC 855
Query: 724 SCDPNWMGPDCSVEV--CSVDCGTHGVCI-----GGACRCEEGWTGAACDQRV--CHPR- 773
C W G C V++ C + HG G C C+ G++G C+ + C P
Sbjct: 856 VCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP 915
Query: 774 CIEHGTCKDG----KCECREGWNGEHC--TIDGC-PDLCNGNGRCTLGQNSWQCVCQTGW 826
C G+C DG C+C G+ G C I+ C D C CT +S+ C C G+
Sbjct: 916 CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGF 975
Query: 827 RGPGCNVAMETSCADNKDNEGDGLVD------CLDPDCCLQSACQNSL 868
G C C ++ G VD CL P S CQ+ +
Sbjct: 976 SGIHCE-NNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDV 1022
Score = 126 bits (316), Expect = 3e-28
Identities = 100/349 (28%), Positives = 133/349 (38%), Gaps = 79/349 (22%)
Query: 576 CPRN-CHGNGECV----SGVCHCFPGFLGADCAK-----AACPVLCSGNG----QYSKGT 621
C N C G+C+ S +CHC P F G C + P LC G +
Sbjct: 144 CASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYR 203
Query: 622 CQCYSGWKGAECDVPMNQCIDPSCGGHGSC-----IDGNCVCSAGYKGEHCEE--VDCLD 674
C C + G C+ P C C G+C + C C G+ G++CEE DC
Sbjct: 204 CVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPG 263
Query: 675 PTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC---PDQCSGHGTYLPDTG--LCSC 725
C + G CV+G C C P W G C +C P+ C GT G C C
Sbjct: 264 NNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC 323
Query: 726 DPNWMGPDCSVEVCSVDCGTHGVCIGGA----------CRCEEGWTGAAC---DQRVCHP 772
W G DCS + DC + C GA C C G TG C D + +P
Sbjct: 324 VNGWTGEDCSENI--DDCAS-AACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNP 380
Query: 773 RCIEHGTCK----DGK--CECREGWNGEHCT--IDGC---PDLCNGNGRCTLGQNSWQCV 821
C E C +GK C C G+ G C+ +D C + C G+C S++C
Sbjct: 381 -CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQ 439
Query: 822 CQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
C G+ GP C + D + C+ + CQN C
Sbjct: 440 CLQGYTGPRCEI---------------------DVNECVSNPCQNDATC 467
Score = 115 bits (288), Expect = 6e-25
Identities = 102/374 (27%), Positives = 141/374 (37%), Gaps = 98/374 (26%)
Query: 573 VQDC---PRNCHGNGECVSGV----CHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQ-- 623
V +C P C G C + V C C G +C + P CS + + GTC+
Sbjct: 179 VNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP--CSPSPCQNGGTCRPT 236
Query: 624 --------CYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHC---- 667
C G+ G C+ ++ C +C G+C+DG NC C + G++C
Sbjct: 237 GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDV 296
Query: 668 EEVDCLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPD---- 719
+E + C + G C N C+C GW G +C C HG D
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVAS 356
Query: 720 ---------TGL-----------------------------CSCDPNWMGPDCS--VEVC 739
TGL C+C + GP CS V+ C
Sbjct: 357 FYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDEC 416
Query: 740 SV---DCGTHGVCIGG----ACRCEEGWTGAACD----QRVCHPRCIEHGTCKDG----K 784
S+ C G CI C+C +G+TG C+ + V +P C TC D +
Sbjct: 417 SLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNP-CQNDATCLDQIGEFQ 475
Query: 785 CECREGWNGEHCTI--DGCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCAD 841
C C G+ G HC + D C C NGRC N +QC C TG+ G C ++ CA
Sbjct: 476 CICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVD-ECAS 534
Query: 842 NKDNEGDGLVDCLD 855
G CLD
Sbjct: 535 TPCKNG---AKCLD 545
Score = 114 bits (284), Expect = 2e-24
Identities = 81/275 (29%), Positives = 114/275 (41%), Gaps = 45/275 (16%)
Query: 599 GADCAKAACPVLCSGNGQYSKGT--CQCYSGWKGAECDVPMNQCIDPSCGGHGSC----- 651
G C++ L G + + GT C C + G C P N C+ C G+C
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDP-NPCLSTPCKNAGTCHVVDR 79
Query: 652 ---IDGNCVCSAGYKGEHCE---EVDCLDPTCSSHGVC-----VNGECLCSPGWGGLNCE 700
D C C+ G+ G C + CL C + G C +C C PGW G +C+
Sbjct: 80 RGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ 139
Query: 701 LARVQCPDQCSGHGTYLP--DTGLCSCDPNWMGPDCSVEVCSVDCGTH-GVCIGGA---- 753
A + C+ G LP + +C C P++ GP C +V +CG G+C G
Sbjct: 140 QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDV--NECGQKPGLCRHGGTCHN 197
Query: 754 ------CRCEEGWTGAACDQRV--CHPR-CIEHGTCK-----DGKCECREGWNGEHC--T 797
C C TG C++ C P C GTC+ +C C G+ G++C
Sbjct: 198 EVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEEN 257
Query: 798 IDGCP-DLCNGNGRCTLGQNSWQCVCQTGWRGPGC 831
ID CP + C G C G N++ C C W G C
Sbjct: 258 IDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC 292
Score = 110 bits (276), Expect = 1e-23
Identities = 104/406 (25%), Positives = 137/406 (33%), Gaps = 110/406 (27%)
Query: 573 VQDCPRN-CHGNGECVSGV----CHCFPGFLGADCAKAA--CPVLCSGNG-----QYSKG 620
V +C C G C G C C G+ G +C C NG +++
Sbjct: 1022 VNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQY 1081
Query: 621 TCQCYSGWKGAECDVPMNQC----------IDPSCGGHGSCIDG----NCVCSAGYKGEH 666
C+C SGW G CDVP C + C G C+D +C C AGY G +
Sbjct: 1082 RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSY 1141
Query: 667 CEEV--DCLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC---PDQCSGHGTYL 717
CE++ +C C + C + C C G+ G+NC +C P Q G L
Sbjct: 1142 CEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDL 1201
Query: 718 PDTGLCSCDPNWMGPDCSVEV--C---------SVDCGTHGVCI----GGACRCEEGWTG 762
P+T CSC G C + V C S C +G C+ G +C C G+ G
Sbjct: 1202 PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVG 1261
Query: 763 AACDQRV-------CHPR----CIEHGTCKDGKCECREGWNGEHC--TIDGCPDL----- 804
C+ V C R C++ D CECR G G C I+GC
Sbjct: 1262 ERCEGDVNECLSNPCDARGTQNCVQR--VNDFHCECRAGHTGRRCESVINGCKGKPCKNG 1319
Query: 805 -------------------------------------CNGNGRCTLGQNSWQCVCQTGWR 827
C G C G S C+C +
Sbjct: 1320 GTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFT 1379
Query: 828 GPGCNVAMETSCADNKDNEGDGLVDCLDPD---CCLQSACQNSLLC 870
GP C + C G + CL A N LLC
Sbjct: 1380 GPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
Score = 102 bits (255), Expect = 4e-21
Identities = 84/317 (26%), Positives = 119/317 (37%), Gaps = 58/317 (18%)
Query: 575 DCPRNCHGNGECVSGV----CHCFPGFLGA-------DCAKAACPVLCSGNGQYSKGTCQ 623
D R C G CV C C G+ G+ +C+ + C + +C+
Sbjct: 1111 DVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCK 1170
Query: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSCID----GNCVCSAGYKGEHCE--EVDC----- 672
C +G+ G C +++C+ C G+C+D C C G +G HCE DC
Sbjct: 1171 CVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVD 1230
Query: 673 ---LDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC-PDQCSGHGT----YLPDT 720
P C ++G CV+ C C PG+ G CE +C + C GT +
Sbjct: 1231 PVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVND 1290
Query: 721 GLCSCDPNWMGPDCS--VEVC-SVDCGTHGVCI-------GGACRCEEGWTGAAC--DQR 768
C C G C + C C G C G C+C G+ GA C D R
Sbjct: 1291 FHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDAR 1350
Query: 769 VCHP-RCIEHGTCKDG----KCECREGWNGEHCTIDGCPDLCNGN-----GRCTLGQNS- 817
C RC+ GTC G C C + G C GN G C S
Sbjct: 1351 TCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESP 1410
Query: 818 -WQCVCQTGWRGPGCNV 833
++C+C + G C++
Sbjct: 1411 FYRCLCPAKFNGLLCHI 1427
Score = 70.1 bits (170), Expect = 3e-11
Identities = 67/264 (25%), Positives = 90/264 (34%), Gaps = 62/264 (23%)
Query: 629 KGAECDVPMNQCIDPSCGGHGSCIDGN--CVCSAGYKGEHCEEVD-CLDPTCSSHGVC-- 683
+G C P C++ GG +G CVC + G C++ + CL C + G C
Sbjct: 20 RGPRCSQPGETCLN---GGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHV 76
Query: 684 ------VNGECLCSPGWGGLNC--ELARVQCPDQCSGHGT--YLPDTGL-CSCDPNWMGP 732
+ C C+ G+ G C L + C GT L T C C P W G
Sbjct: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 733 DCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHG-TCKDGKCECREGW 791
C + C ++ GG C E +CH HG TC+ EC +
Sbjct: 137 SCQQ---ADPCASNPCANGGQCLPFEA-------SYICHCPPSFHGPTCRQDVNECGQK- 185
Query: 792 NGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLV 851
P LC G C S++CVC+ GP C
Sbjct: 186 ----------PGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP-------------- 221
Query: 852 DCLDPDCCLQSACQNSLLCRGSRD 875
C S CQN CR + D
Sbjct: 222 -------CSPSPCQNGGTCRPTGD 238
Score = 38.5 bits (88), Expect = 0.093
Identities = 52/204 (25%), Positives = 79/204 (38%), Gaps = 33/204 (16%)
Query: 178 SLLPSAQLPSSHNP-------PPVSCQMPLLD------------SNTSHQIMDTN--PDE 216
S L S +P+ +NP P+S Q P L ++ Q+M P
Sbjct: 2312 SRLQSGMVPNQYNPLRGSVAPGPLSTQAPSLQHGMVGPLHSSLAASALSQMMSYQGLPST 2371
Query: 217 EFSPNSYLLRACS-GPQ----QASSSGPPNHHSQSTLRPPLPPPHNHTLSHHHSSANSLN 271
+ +L++ PQ Q + P N Q +L+PP PPP H L +++ L
Sbjct: 2372 RLATQPHLVQTQQVQPQNLQMQQQNLQPANIQQQQSLQPPPPPPQPH-LGVSSAASGHLG 2430
Query: 272 RNSLTNRRSQIHAPAPAPNDLAT----TPESVQLQDSWVLNSNVPLETRHFLFKTS--SG 325
R+ L+ SQ P+ LA ES L S + P+ FL S S
Sbjct: 2431 RSFLSGEPSQADVQPLGPSSLAVHTILPQESPALPTSLPSSLVPPVTAAQFLTPPSQHSY 2490
Query: 326 STPLFSSSSPGYPLTSGTVYTPPP 349
S+P+ ++ S + TP P
Sbjct: 2491 SSPVDNTPSHQLQVPEHPFLTPSP 2514
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 149 bits (375), Expect = 5e-35
Identities = 99/344 (28%), Positives = 148/344 (43%), Gaps = 57/344 (16%)
Query: 572 SVQDCPRN-CHGNGEC---VSG-VCHCFPGFLGADCAKAACP---------VLCSGNGQY 617
++ +C N C G C +SG CHC + G +C P +C + +
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNF 854
Query: 618 SKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHCEE--VD 671
TC C GW+G C + +++CI C HG C + C C G+ G CEE D
Sbjct: 855 ESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDD 914
Query: 672 CLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC-PDQCSGHGTY--LPDTGLCS 724
CL C + G C++G CLC PG+ G C+ +C + C GT ++ C
Sbjct: 915 CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCK 974
Query: 725 CDPNWMGPDC--SVEVCS-VDCGTHGVCIGG----ACRCEEGWTGAACDQRV----CHPR 773
C + G C ++ C+ C G C+ G +C C G+TG+ C + HP
Sbjct: 975 CQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHP- 1033
Query: 774 CIEHGTCKDG----KCECREGWNGEHC--TIDGCP-DLCNGNGRCTLGQNSWQCVCQTGW 826
C+ GTC DG +C C G+ G++C ++ C C G C + QC+C +GW
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
Query: 827 RGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
G C+V SC G ++ CQ+S +C
Sbjct: 1094 AGAYCDVP-NVSCDIAASRRG----------VLVEHLCQHSGVC 1126
Score = 136 bits (342), Expect = 3e-31
Identities = 106/360 (29%), Positives = 148/360 (41%), Gaps = 64/360 (17%)
Query: 573 VQDCPRNCHGNGECVSGV----CHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQ----- 623
V +C N +G C G+ C C G++G +C C N + GTC
Sbjct: 721 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNE--CLSNPCQNGGTCDNLVNG 778
Query: 624 ----CYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEV--DCL 673
C G+KG C V +++C C G+C D C C Y G++C+ V C
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCS 838
Query: 674 DPTCSSHGVCVNG------ECLCSPGWGGLNCELARVQCPDQ-CSGHGTYLPDTG--LCS 724
C + VC CLC+PGW G C + +C + C HG G +C
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCE 898
Query: 725 CDPNWMGPDCSVEV--CSVD-CGTHGVCIGG----ACRCEEGWTGAAC--DQRVC-HPRC 774
C P + G DC ++ C + C G C+ G +C C G+TG C D C C
Sbjct: 899 CPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPC 958
Query: 775 IEHGTCKD----GKCECREGWNGEHC--TIDGCPD-LCNGNGRCTLGQNSWQCVCQTGWR 827
GTC D C+C+ G++G HC I+ C + C G C G NS+ C+C G+
Sbjct: 959 KNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT 1018
Query: 828 GPGCNVAMETSCADNKDNEG---DGL--VDCLDP------------DCCLQSACQNSLLC 870
G C + + NEG DGL C P + C +S C+N C
Sbjct: 1019 GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC 1078
Score = 135 bits (339), Expect = 7e-31
Identities = 101/347 (29%), Positives = 139/347 (40%), Gaps = 57/347 (16%)
Query: 580 CHGNGECVSGV----CHCFPGFLGA-------DCAKAACPVLCSGNGQYSKGTCQCYSGW 628
C G+CV+ C C G+ G +C C + + TC C G+
Sbjct: 427 CEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGF 486
Query: 629 KGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHC--EEVDCLDPTCSSHGV 682
KG C++ +N+C C +G C+D C+C G+ G C + DC C +
Sbjct: 487 KGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAK 546
Query: 683 CV---NG-ECLCSPGWGGLNCELARVQC-PDQCSGHGTYLP--DTGLCSCDPNWMGPDCS 735
C+ NG EC C+ G+ G+ CE C PD C HG D+ C C+P +MG CS
Sbjct: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCH-HGQCQDGIDSYTCICNPGYMGAICS 605
Query: 736 --VEVC-SVDCGTHGVCI----GGACRCEEGWTGAACDQRV--CHPRCIEHGTCKDG--- 783
++ C S C G CI G C C+ G +G C+ C HG C DG
Sbjct: 606 DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINR 665
Query: 784 -KCECREGWNGEHCTID---GCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC----NVAM 835
C C G+ G+ C ID + C C G N ++C+C G P C N +
Sbjct: 666 YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECL 725
Query: 836 ETSCADNKDNEGDGLVDCL------------DPDCCLQSACQNSLLC 870
C G CL D + CL + CQN C
Sbjct: 726 SNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTC 772
Score = 131 bits (330), Expect = 8e-30
Identities = 100/359 (27%), Positives = 134/359 (37%), Gaps = 71/359 (19%)
Query: 580 CHGNGECVS-----GVCHCFPGFLGA------DCAKAACPV--LCSGNGQYSKGTCQCYS 626
C G CV+ G C C GFLG C K C C K TC+C S
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 627 GWKGAECDVPMNQ--CIDPSCGGHGSC-----IDGNCVCSAGYKGEHCEEVD-CLDPTCS 678
G+ G +C + + C G+C C C G+ G+ C+ D CL C+
Sbjct: 95 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154
Query: 679 SHGVCV----NGECLCSPGWGGLNCELARVQC--PDQCSGHGT--YLPDTGLCSCDPNWM 730
+ C C C G+ G CE +C P C GT LP + C C +
Sbjct: 155 NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
Query: 731 GPDCSVEVCSVDCGTHGVCIGGACR----------CEEGWTGAACDQRV--C-HPRCIEH 777
G C + V C GG CR C G+ G+ C++ + C + RC
Sbjct: 215 GQYC--DSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNG 272
Query: 778 GTCKDG----KCECREGWNGEHCT--IDGC---PDLCNGNGRCTLGQNSWQCVCQTGWRG 828
G C DG C C W G+ CT +D C P+ C G C + CVC GW G
Sbjct: 273 GVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSG 332
Query: 829 PGCNVAMETSCADNKDNEGDGLVD------CLDP-----------DCCLQSACQNSLLC 870
C+ ++ CA G +D C+ P D C+ + C LC
Sbjct: 333 DDCSENID-DCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALC 390
Score = 128 bits (321), Expect = 9e-29
Identities = 97/348 (27%), Positives = 142/348 (40%), Gaps = 68/348 (19%)
Query: 571 DSVQDC-PRNCHGNGECVSGV----CHCFPGFLGADCAKA-----ACPVLCSGN--GQYS 618
+++ +C P CH +G+C G+ C C PG++GA C+ + P L G +
Sbjct: 569 ENIDNCDPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVN 627
Query: 619 KGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE-EVD-C 672
C C G G C++ + C C HG C+DG +CVCS G+ G+ C ++D C
Sbjct: 628 GYQCNCQPGTSGVNCEINFDDCASNPCI-HGICMDGINRYSCVCSPGFTGQRCNIDIDEC 686
Query: 673 LDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTG--LCSCD 726
C C+NG C+C G +C +C HG C CD
Sbjct: 687 ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCD 746
Query: 727 PNWMGPDCSV---EVCSVDCGTHGVCI----GGACRCEEGWTGAAC----DQRVCHPRCI 775
W+G +C V E S C G C G C C++G+ G C D+ +P C+
Sbjct: 747 AGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNP-CL 805
Query: 776 EHGTCKDG----KCECREGWNGEHC--TIDGC-PDLCNGNGRCTLGQN--SWQCVCQTGW 826
GTC D C C + G++C + C P+ C C N S+ C+C GW
Sbjct: 806 NQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865
Query: 827 RGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSR 874
+G C + D D C+ C N LC ++
Sbjct: 866 QGQRCTI---------------------DIDECISKPCMNHGLCHNTQ 892
Score = 126 bits (317), Expect = 3e-28
Identities = 96/345 (27%), Positives = 137/345 (39%), Gaps = 64/345 (18%)
Query: 572 SVQDCPRN-CHGNGECVSGV----CHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQ--- 623
++ DCP + C G CV GV C C P + G C + L N + GTC
Sbjct: 260 NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRN 319
Query: 624 ------CYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEVD-C 672
C +GW G +C ++ C SC +CID +C+C G G C D C
Sbjct: 320 GGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDAC 379
Query: 673 LDPTCSSHGVC----VNGE--CLCSPGWGGLNCELARVQC----PDQCSGHGTYLPDTGL 722
+ C +C +NG+ C C G+ G +C +C + C G + G
Sbjct: 380 ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGA 439
Query: 723 --CSCDPNWMGPDCSVEV--CSVD-CGTHGVCI----GGACRCEEGWTGAACDQRV--CH 771
C C + GP C +++ C D C C+ G C C G+ G C+ + C
Sbjct: 440 FHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQ 499
Query: 772 PR-CIEHGTCKDG----KCECREGWNGEHC--TIDGCPDL-CNGNGRCTLGQNSWQCVCQ 823
C+ +G C D +C C G+ G C ID C C +C N ++C C
Sbjct: 500 SNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCA 559
Query: 824 TGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSL 868
TG+ G C +N DN DPD C CQ+ +
Sbjct: 560 TGFTG--------VLCEENIDN--------CDPDPCHHGQCQDGI 588
Score = 117 bits (292), Expect = 2e-25
Identities = 91/330 (27%), Positives = 133/330 (40%), Gaps = 44/330 (13%)
Query: 591 CHCFPGFLGADCAKA-ACPVLCSGNGQY-----SKGTCQCYSGWKGAECDVPMNQCIDPS 644
C C GF G +C AC NG ++ +C+C +G+ G +C+ +N+C P
Sbjct: 131 CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 190
Query: 645 -CGGHGSCID----GNCVCSAGYKGEHCEE--VDCLDPTCSSHGVC-----VNGECLCSP 692
C G+C++ C C G+ G++C+ V C C + G C EC C P
Sbjct: 191 HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250
Query: 693 GWGGLNCELARVQCPD-QCSGHGTYLP--DTGLCSCDPNWMGPDCS--VEVCSVD---CG 744
G+ G CE CP+ +C G + +T C C P W G C+ V+ C + C
Sbjct: 251 GFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310
Query: 745 THGVCI----GGACRCEEGWTGAACDQRV---CHPRCIEHGTCKDG----KCECREGWNG 793
G C G C C GW+G C + + C TC D C C EG G
Sbjct: 311 NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370
Query: 794 EHCTIDGC--PDLCNGNGRCTLGQNSWQ--CVCQTGWRGPGCNVAMETSCADNKDNEGDG 849
C +D + C+ C + Q C C G++G C ++ CA N +
Sbjct: 371 LLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD-ECAMANSNPCEH 429
Query: 850 LVDCLDPDCCLQSACQNSLLCRGSRDPLDI 879
C++ D C G R +DI
Sbjct: 430 AGKCVNTDGAFHCECLKGY--AGPRCEMDI 457
Score = 97.1 bits (240), Expect = 2e-19
Identities = 89/341 (26%), Positives = 131/341 (38%), Gaps = 66/341 (19%)
Query: 580 CHGNGECVSG----VCHCFPGFLGA-------DCAKAACPVLCSGNGQYSKGTCQCYSGW 628
C +G C++ C C G+ G+ +CA C + + C+C G+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
Query: 629 KGAECDVPMNQCIDPSCGGHGSCID----GNCVCSAGYKGEHCEE--VDCL-DPTCSSHG 681
+G C+ +++C + C G+CID C C G +G CEE DC P C + G
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGG 1239
Query: 682 VCVNG----ECLCSPGWGGLNCELARVQC-PDQCSGHGT----YLPDTGLCSCDPNWMGP 732
C++ C C PG+ G CE +C + CS G+ L + LC C + G
Sbjct: 1240 QCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGR 1299
Query: 733 DCS--VEVC-SVDCGTHGVCI-------GGACRCEEGWTGAACDQRVCHPRCIEHGTC-- 780
C V+VC + C G C G CRC G++GA C +C + C
Sbjct: 1300 HCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVH 1359
Query: 781 --KDGKCECREGWNGEHCTIDGCPDL-CNGNGRCTLGQNS--WQCVCQTGWRGPGCNV-- 833
+C C + E GC C G C + + C C + G C +
Sbjct: 1360 TASGPRCFCPSPRDCE----SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
Query: 834 ---------AMETSCADNKDNEGDGLVDCLDPDCCLQSACQ 865
+ CA D DG+ D + C ACQ
Sbjct: 1416 APPSTPPATCLSQYCA---DKARDGVCD----EACNSHACQ 1449
Score = 69.7 bits (169), Expect = 4e-11
Identities = 48/154 (31%), Positives = 62/154 (40%), Gaps = 26/154 (16%)
Query: 704 VQCPD---QCSGHG---TYLPDTGLCSCDPNWMGPDCSV-EVCSVD-CGTHGVCIGGA-- 753
+QC D C G TY TG C C ++G C + C + C G C+ A
Sbjct: 26 LQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAML 85
Query: 754 ----CRCEEGWTGAACDQRVCHP-----RCIEHGTC-----KDGKCECREGWNGEHCT-I 798
CRC G+TG C HP C+ GTC +C C+ G+ G+ C
Sbjct: 86 GKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT 145
Query: 799 DGC-PDLCNGNGRCTLGQNSWQCVCQTGWRGPGC 831
D C C CT N + C C TG+ G C
Sbjct: 146 DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKC 179
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 142 bits (357), Expect = 6e-33
Identities = 101/331 (30%), Positives = 142/331 (42%), Gaps = 63/331 (19%)
Query: 593 CFPGFLGADCAKAACPVLCSGNGQYSK--GTCQCYSGWKGAECDVPMNQCI-DPSCGGHG 649
C G++G +C +A C CS K G C+C GW+G CD +CI P C HG
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCD----KCIPHPGC-VHG 274
Query: 650 SCID-GNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNG-----------ECLCSPGWGGL 697
C + C+C + G+ C++ D C +H C+NG +C C G+ G
Sbjct: 275 ICNEPWQCLCETNWGGQLCDK-DL--NYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGP 331
Query: 698 NCELARVQC-PDQCSGHGTYLPDTGL---CSCDPNWMGPDCSVEV--CSVDCGTHG---- 747
NCE+A C D C G+ +T L C C P W GP CS + CS + +HG
Sbjct: 332 NCEIAEHACLSDPCHNRGS-CKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQ 390
Query: 748 -VCIGGACRCEEGWTGAAC--DQRVCHPR-CIEHGTCKD----GKCECREGWNGEHC--T 797
+ G C C WTG C D C + C+ +CK+ C+C GW G++C
Sbjct: 391 DLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 450
Query: 798 IDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG---------- 847
I+ C C + C N ++C+C G+ G C ++ CA N G
Sbjct: 451 INDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDID-ECASNPCLNGGHCQNEINRF 509
Query: 848 --------DGLVDCLDPDCCLQSACQNSLLC 870
G + LD D C + CQN C
Sbjct: 510 QCLCPTGFSGNLCQLDIDYCEPNPCQNGAQC 540
Score = 137 bits (346), Expect = 1e-31
Identities = 110/384 (28%), Positives = 150/384 (39%), Gaps = 109/384 (28%)
Query: 572 SVQDC-PRNCHGNGEC---VSGV-CHCFPGFLGADCAKAA--CPVLCSGNGQYSKGT--- 621
++ DC P NC G C V+G C C P + G C A C N + K
Sbjct: 374 NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIAS 433
Query: 622 --CQCYSGWKGAECDVPMNQCIDPSCGGHGSCID----GNCVCSAGYKGEHCE-EVD-CL 673
C C GW G CD+ +N C+ C SC D C+C GY G+HCE ++D C
Sbjct: 434 YYCDCLPGWMGQNCDININDCLG-QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 674 DPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC-PDQC-SGHGTYLPDTG-LCSCD 726
C + G C N +CLC G+ G C+L C P+ C +G Y + C C
Sbjct: 493 SNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCP 552
Query: 727 PNWMGPDCS-------------VEVCSVD-----------------CGTHGVC---IGG- 752
++ G +CS ++ C+V CG HG C GG
Sbjct: 553 EDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGK 612
Query: 753 -ACRCEEGWTGAACDQRV--CHPR-CIEHGTCKDG----KCECREGWNGEHCTID----- 799
C C +G+TG C + + C C GTC DG KC C +GW G +C +
Sbjct: 613 FTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCS 672
Query: 800 --------GCPDL----------------------------CNGNGRCTLGQNSWQCVCQ 823
C DL CN G C ++++C+C
Sbjct: 673 QNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCP 732
Query: 824 TGWRGPGCNVAMETSCADNKDNEG 847
GW G CN+A +SC N + G
Sbjct: 733 GGWEGTTCNIARNSSCLPNPCHNG 756
Score = 130 bits (327), Expect = 2e-29
Identities = 97/309 (31%), Positives = 123/309 (39%), Gaps = 39/309 (12%)
Query: 619 KGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEV--DC 672
K TC C G+ G C +N C C G+CIDG C+CS G++G +CE DC
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDC 671
Query: 673 LDPTCSSHGVC---VNG-ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTG---LCSC 725
C + G C VN C C GW G C QC + +G D G C C
Sbjct: 672 SQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 726 DPNWMGPDCSVEVCSV----DCGTHGVCIGGA----CRCEEGWTGAACDQRV--CHPR-C 774
W G C++ S C G C+ C C+EGW G C Q C P C
Sbjct: 732 PGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPC 791
Query: 775 IEHGTCKDG----KCECREGWNGEHC--TIDGCPDL-CNGNGRCTLGQNSWQCVCQTGWR 827
GTC DG +CEC G+ G C I+ C C C N ++CVC G
Sbjct: 792 YNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHS 851
Query: 828 GPGCNVAMETSCADNKDNEGDGLVDCLDPDC----CLQSACQNSLLCRGSRDPLDIIQQG 883
G C C DG D DC CL S + G R L + +G
Sbjct: 852 GAKCQEVSGRPCITMGSVIPDGAK--WDDDCNTCQCLNGRIACSKVWCGPRPCL--LHKG 907
Query: 884 QTDWPAVKS 892
++ P+ +S
Sbjct: 908 HSECPSGQS 916
Score = 114 bits (286), Expect = 1e-24
Identities = 84/298 (28%), Positives = 121/298 (40%), Gaps = 46/298 (15%)
Query: 580 CHGNGECVSGVCH------CFPGFLGADCAKAA--C----PVL----CSGNGQYSKGTCQ 623
C + CV G+C+ C + G C K C P L CS G K C
Sbjct: 265 CIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP-DKYQCS 323
Query: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSC----IDGNCVCSAGYKGEHCEE--VDCLDPTC 677
C G+ G C++ + C+ C GSC + C CS G+ G C DC C
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNC 383
Query: 678 SSHGVC---VNG-ECLCSPGWGGLNCELARVQC---PDQCSGHGTYLPDTGLCSCDPNWM 730
S G C VNG +C+C P W G C+L +C P + L + C C P WM
Sbjct: 384 SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWM 443
Query: 731 GPDCSVEV------CSVDCGTHGVCIGGACRCEEGWTGAACDQRV---CHPRCIEHGTCK 781
G +C + + C D + G C C G+ G C++ + C+ G C+
Sbjct: 444 GQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQ 503
Query: 782 DG----KCECREGWNGEHC--TIDGC-PDLCNGNGRCTLGQNSWQCVCQTGWRGPGCN 832
+ +C C G++G C ID C P+ C +C + + C C + G C+
Sbjct: 504 NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCS 561
Score = 100 bits (248), Expect = 3e-20
Identities = 58/178 (32%), Positives = 79/178 (44%), Gaps = 13/178 (7%)
Query: 690 CSPGWGGLNCELARVQCPDQCSGHGTYLPD-TGLCSCDPNWMGPDCSVEVCSVDCGT-HG 747
C + G C C + G Y D G +C WMGP+C+ +C C HG
Sbjct: 187 CDDYYYGFGCNKF---CRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHG 243
Query: 748 VC-IGGACRCEEGWTGAACDQRVCHPRCIEHGTCKD-GKCECREGWNGEHCTID----GC 801
C + G CRC+ GW G CD+ + HP C+ HG C + +C C W G+ C D G
Sbjct: 244 SCKLPGDCRCQYGWQGLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGT 302
Query: 802 PDLCNGNGRCT-LGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC 858
C G C+ G + +QC C G+ GP C +A +D N G L +C
Sbjct: 303 HQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360
Score = 92.4 bits (228), Expect = 5e-18
Identities = 67/219 (30%), Positives = 90/219 (41%), Gaps = 22/219 (10%)
Query: 658 CSAGYKGEHCEEVDCLDPTCSSHGVC-VNGECLCSPGWGGLNCELARVQCPDQCSG-HGT 715
C Y G C + H C NG C GW G C R C CS HG+
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHGS 244
Query: 716 Y-LPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGG-ACRCEEGWTGAACDQRV---- 769
LP G C C W G C + C HG+C C CE W G CD+ +
Sbjct: 245 CKLP--GDCRCQYGWQGLYCDKCIPHPGC-VHGICNEPWQCLCETNWGGQLCDKDLNYCG 301
Query: 770 CHPRCIEHGTCKDG-----KCECREGWNGEHCTI--DGC-PDLCNGNGRCTLGQNSWQCV 821
H C+ GTC + +C C EG++G +C I C D C+ G C ++C
Sbjct: 302 THQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECE 361
Query: 822 CQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCL 860
C GW GP C+ ++ C+ N + G D ++ C+
Sbjct: 362 CSPGWTGPTCSTNID-DCSPNNCSHGGTCQDLVNGFKCV 399
Score = 72.8 bits (177), Expect = 4e-12
Identities = 59/201 (29%), Positives = 81/201 (40%), Gaps = 52/201 (25%)
Query: 577 PRNCHGNGECV----SGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTC---------Q 623
P CH G CV S C C G+ G CA+ CS + Y+ GTC +
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND--CSPHPCYNSGTCVDGDNWYRCE 807
Query: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEVD---CL--- 673
C G+ G +C + +N+C C +C+D CVC G+ G C+EV C+
Sbjct: 808 CAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMG 867
Query: 674 ---------DPTCSSHGVCVNGECLCSPGW-GGLNCEL--ARVQCP----------DQCS 711
D C++ C+NG CS W G C L +CP DQC
Sbjct: 868 SVIPDGAKWDDDCNT-CQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCF 926
Query: 712 GHGTYLPDTGLCSCDPNWMGP 732
H P TG+ C + + P
Sbjct: 927 VH----PCTGVGECRSSSLQP 943
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 139 bits (350), Expect = 4e-32
Identities = 101/353 (28%), Positives = 130/353 (36%), Gaps = 96/353 (27%)
Query: 574 QDCPRNCHGNG-------------ECVSGVCHCFPGFLGADCAKAA--------CPVLCS 612
+ CP++ HG G + SG+C C PG+ G CA C CS
Sbjct: 393 ESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCS 452
Query: 613 GNGQYS----KGTCQCYSGWKGAECDVPMNQCI-DPSCGGHGSCID--------GNCVCS 659
+ G C C GW+ C VP SC C G C C+
Sbjct: 453 CENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCT 512
Query: 660 AGYKGEHCEEVDC----LDPTCSSHGVC--------VNGECLCSPGWGGLNCELARVQCP 707
G+ G HC+ + C C+S C V+G C C GW G C L+ CP
Sbjct: 513 PGWHGAHCQ-LPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLS---CP 568
Query: 708 D-----------QCSGHGTYLPDTGLCSCDPNWMGPDCS---------VEVCSVDCGTHG 747
+ C GT LP+ G C C P + GP C C H
Sbjct: 569 EGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHS 628
Query: 748 VC--IGGACRCEEGWTGAACDQRVCHP-----------RCIEHGTC--KDGKCECREGWN 792
C G C C GWTG C Q C P +C GTC +DG C C GW
Sbjct: 629 FCHPSNGTCYCLAGWTGPDCSQP-CPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWT 687
Query: 793 GEHCTIDGCP-----DLCNGNGRCTLGQN----SWQCVCQTGWRGPGCNVAME 836
G HC ++GCP C+ +C G+ + CVC G G C + ++
Sbjct: 688 GHHC-LEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQ 739
Score = 128 bits (321), Expect = 9e-29
Identities = 96/342 (28%), Positives = 121/342 (35%), Gaps = 88/342 (25%)
Query: 574 QDCPRNCH--GNGEC--VSGVCHCFPGFLGADCAKAACP---------VLCSGNGQYS-- 618
QDC C + C +G C C GF G C CP C+ + ++S
Sbjct: 313 QDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS 372
Query: 619 ----KGTCQCYSGWKGAECDVPMNQCID-PSCGGHGSCIDGN--------CVCSAGYKGE 665
G C C GW G C+ Q P C H C+ G C C+ GY G
Sbjct: 373 CHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGP 432
Query: 666 HCEEV---DCLDPTCSSHGVCVN--------GECLCSPGWGGLNCELARVQCPD------ 708
HC + D CS+ C N GEC+C GW NC V CP
Sbjct: 433 HCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCS---VPCPPGTWGFS 489
Query: 709 -----QCSGHGTYLPDTGLCSCDPNWMGPDCSV--------EVCS--VDCGTHGVC--IG 751
QC+ P TG C+C P W G C + E C+ DC C +
Sbjct: 490 CNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVH 549
Query: 752 GACRCEEGWTGAACD------------QRVCHPRCIEHGTC--KDGKCECREGWNGEHCT 797
G C+C+ GW GA C C C GTC ++G C C G+ G C
Sbjct: 550 GRCQCQAGWMGARCHLSCPEGLWGVNCSNTC--TCKNGGTCLPENGNCVCAPGFRGPSCQ 607
Query: 798 IDGCPDL-------CNGNGRCTLGQNSWQCVCQTGWRGPGCN 832
P C ++ C C GW GP C+
Sbjct: 608 RSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCS 649
Score = 123 bits (309), Expect = 2e-27
Identities = 90/321 (28%), Positives = 121/321 (37%), Gaps = 88/321 (27%)
Query: 574 QDCPRNCHGNGEC--VSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGA 631
Q+C CH G C +G C C PG+ G C + CPV GQ TC C
Sbjct: 274 QEC--RCHNGGLCDRFTGQCRCAPGYTGDRC-REECPV--GRFGQDCAETCDC------- 321
Query: 632 ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDP----TCSSHGVC---- 683
P +C + G C+C G+ G+ C + C D +C + C
Sbjct: 322 ---APDARCFPAN---------GACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREH 369
Query: 684 ------VNGECLCSPGWGGLNCELARVQCPDQ-----CSGH------GTYLPDTGLCSCD 726
+NGEC C PGW GL+C CP C H G +GLC C
Sbjct: 370 SLSCHPMNGECSCLPGWAGLHC---NESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCA 426
Query: 727 PNWMGPDCS----VEVCSVDCGTHGVC--------IGGACRCEEGWTGAACDQRVCHP-- 772
P + GP C+ + V+C C I G C C+EGW C C P
Sbjct: 427 PGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV-PCPPGT 485
Query: 773 ---------RCIEHGTC--KDGKCECREGWNGEHCTI--------DGCPDLCNGNGRCTL 813
+C C + G C C GW+G HC + +GC C+ +
Sbjct: 486 WGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGC 545
Query: 814 GQNSWQCVCQTGWRGPGCNVA 834
+C CQ GW G C+++
Sbjct: 546 DPVHGRCQCQAGWMGARCHLS 566
Score = 119 bits (298), Expect = 4e-26
Identities = 107/375 (28%), Positives = 132/375 (35%), Gaps = 100/375 (26%)
Query: 576 CPRNCHGNGECVS-GVCHCFPGFLGADCAKAACPVL----------CSGNGQY--SKGTC 622
C + C +G CV+ C C PG+ G DC+ P + C N G C
Sbjct: 105 CAQECV-HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVC 163
Query: 623 QCYSGWKGAECDVP-----MNQCIDPSCGGHGSCID---GNCVCSAGYKGEHCEEVDCLD 674
C SG + C P C HG+ D G C C A G C +V C
Sbjct: 164 SCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSC-DVSCSQ 222
Query: 675 PT----CSSHGVCVN--------GECLCSPGWGGLNCELARVQ------CPDQCSGHGTY 716
T C S C N G C C PGW G C L + C +C H
Sbjct: 223 GTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG 282
Query: 717 LPD--TGLCSCDPNWMGPDCSVEVCSV-----------DCGTHGVCI--GGACRCEEGWT 761
L D TG C C P + G C E C V DC C GAC CE G+T
Sbjct: 283 LCDRFTGQCRCAPGYTGDRCR-EECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFT 341
Query: 762 GAACDQRVCHP-----RCIEHGTC----------KDGKCECREGWNGEHCTIDGCPD--- 803
G C R+C C TC +G+C C GW G HC + CP
Sbjct: 342 GDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN-ESCPQDTH 400
Query: 804 --------LCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLD 855
LC G C S C C G+ GP C + C D
Sbjct: 401 GPGCQEHCLCLHGGVCQ--ATSGLCQCAPGYTGPHC----ASLCPP----------DTYG 444
Query: 856 PDCCLQSACQNSLLC 870
+C + +C+N++ C
Sbjct: 445 VNCSARCSCENAIAC 459
Score = 57.4 bits (137), Expect = 2e-07
Identities = 69/273 (25%), Positives = 83/273 (30%), Gaps = 75/273 (27%)
Query: 635 VPMNQCIDPSCGGHGSCIDGNCVCSAGY----KGEHCEEVDCLDPTCSSHGVCVNGECLC 690
+P C P G H +C V Y K +H + + C S G CV LC
Sbjct: 50 LPSEPCERPWEGPH-TCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVP---LC 105
Query: 691 SPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVC----------S 740
+ C R P+QC C P W G DCS E
Sbjct: 106 AQ-----ECVHGRCVAPNQCQ-------------CVPGWRGDDCSSECAPGMWGPQCDKP 147
Query: 741 VDCGTHGVC--IGGACRCEEGWTGAACDQ--------RVCHPRCIEHGTCKD---GKCEC 787
CG + C G C C G C Q C RC HG D G C C
Sbjct: 148 CSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFC 207
Query: 788 REGWNGEHCTID--------GCPDL--CNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMET 837
G C + CP C G Q S C C GW G C++
Sbjct: 208 PAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS--CSCPPGWMGTICSL---- 261
Query: 838 SCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
C + P+C + C N LC
Sbjct: 262 PCPEGFHG----------PNCSQECRCHNGGLC 284
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 136 bits (343), Expect = 3e-31
Identities = 107/378 (28%), Positives = 140/378 (37%), Gaps = 105/378 (27%)
Query: 576 CPRNCHGNGEC--VSGVCHCFPGFLGADCAKAA------------CPVLCSGNGQYSKGT 621
CP C G C ++G C C PG+ GA CA+ CP G + G
Sbjct: 232 CP--CQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQ 289
Query: 622 CQCYSGWKGAECD---------VPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDC 672
C C +G+ G C +Q D GG S G C C GYKG C+E C
Sbjct: 290 CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLC 349
Query: 673 LD----PTCSSHGVC----------VNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLP 718
+ P C+ C V G C C PGW G +C CP G G LP
Sbjct: 350 PEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC---NESCPVGYYGDGCQLP 406
Query: 719 -----------DTGLCSCDPNWMGPDCSV------------EVCSVDCGTHGVC--IGGA 753
TG C+C P +MG C+V +CS C G C + G+
Sbjct: 407 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICS--CNNGGTCSPVDGS 464
Query: 754 CRCEEGWTG----AACDQRVCHPRCIEHGTCK--------DGKCECREGWNGEHCTIDGC 801
C C+EGW G C C E TC DG C C GW G+ C + C
Sbjct: 465 CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELP-C 523
Query: 802 PD-----LCNGNGRCTLGQN----SWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVD 852
PD C+ + C+ + C C GW G C +++C +
Sbjct: 524 PDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRC----DSTCPPGR--------- 570
Query: 853 CLDPDCCLQSACQNSLLC 870
P+C + +C+N C
Sbjct: 571 -WGPNCSVSCSCENGGSC 587
Score = 134 bits (337), Expect = 1e-30
Identities = 106/357 (29%), Positives = 134/357 (37%), Gaps = 97/357 (27%)
Query: 570 LDSVQDCPR-----NCHGNGECVSGV--------CHCFPGFLGADCAKAACP-----VLC 611
LD CP NC+ + C +G C C PG+LG C + CP + C
Sbjct: 474 LDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCPDGTFGLNC 532
Query: 612 SGNGQYSK--------GTCQCYSGWKGAECDVPM-------NQCIDPSCGGHGSCI--DG 654
S + S G C C +GW G CD N + SC GSC DG
Sbjct: 533 SEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG 592
Query: 655 NCVCSAGYKGEHCEEVDCLDPTCSSHG------VCVN---------GECLCSPGWGGLNC 699
+C C+ G++G C+ + P HG +CV+ G C C PG+ G C
Sbjct: 593 SCECAPGFRGPLCQRI--CPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALC 650
Query: 700 ELARV------QCPDQCS--GHGTYLPDTGLCSCDPNWMGPDCS------------VEVC 739
C CS +GT P G C C P W+G DCS C
Sbjct: 651 NQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHAC 710
Query: 740 SVDCGTHGVCIGGACRCEEGWTGAACDQ------------RVCHPRCIEHGTCK--DGKC 785
S G GAC C GWTG C Q RVC +C +C GKC
Sbjct: 711 SCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVC--QCQNGASCDHISGKC 768
Query: 786 ECREGWNGEHCTID--------GCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVA 834
CR G+ G+HC GC LC T + C C G++G C+ A
Sbjct: 769 TCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQA 825
Score = 133 bits (335), Expect = 2e-30
Identities = 110/355 (30%), Positives = 138/355 (38%), Gaps = 102/355 (28%)
Query: 576 CPRNCHGNGECVS-GVCHCFPGFLGADCAKAACPVLCSGN--GQYSKGTCQCYSGWKGAE 632
C C +G CVS CHC PG+ G DC+ C + G + CQC + GA
Sbjct: 103 CTEECV-HGRCVSPDTCHCEPGWGGPDCSSG-----CDSDHWGPHCSNRCQCQN---GAL 153
Query: 633 CDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEV--------DCLDPTCSSHGVCV 684
C+ I G CVC+AG++G CEE+ C P HG
Sbjct: 154 CNP----------------ITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASC 197
Query: 685 N---GECLCSPGWGGLNCE----------LARVQCPDQCSGHGTYLPDTGLCSCDPNWMG 731
+ GECLC+PG+ G+ CE ++CP C GT TG C+C P W G
Sbjct: 198 DPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCP--CQNGGTCHHITGECACPPGWTG 255
Query: 732 PDCSV--------EVCSVDCGTH--GVC--IGGACRCEEGWTGAACDQRV--------CH 771
C+ + CS DC H G C + G C C G+ G C + C
Sbjct: 256 AVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS 315
Query: 772 PRCIEH--GTCK--DGKCECREGWNGEHCTIDGCPDLCNGNGRCTL-----GQN------ 816
C H G C G CEC G+ G C CP+ +G G CTL N
Sbjct: 316 QHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPG-CTLPCPCDADNTISCHP 374
Query: 817 -SWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
+ C CQ GW G CN SC +G C L CQN C
Sbjct: 375 VTGACTCQPGWSGHHCN----ESCPVGYYGDG----------CQLPCTCQNGADC 415
Score = 131 bits (330), Expect = 8e-30
Identities = 111/387 (28%), Positives = 142/387 (36%), Gaps = 104/387 (26%)
Query: 552 AFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGEC--VSGVCHCFPGFLGADCAKAACPV 609
A Y + +E F + Q C +CH G+C +G C C PG+ G C + CP
Sbjct: 294 AGYMGDRCQEECPFGSFGFQCSQHC--DCHNGGQCSPTTGACECEPGYKGPRCQERLCPE 351
Query: 610 LCSGNG---------------QYSKGTCQCYSGWKGAECD--VPMNQCIDP-----SCGG 647
G G G C C GW G C+ P+ D +C
Sbjct: 352 GLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQN 411
Query: 648 HGSC--IDGNCVCSAGYKGEHCEEVDCLDPT----------CSSHGVC--VNGECLCSPG 693
C I G C C+ G+ GE C V C T C++ G C V+G C C G
Sbjct: 412 GADCHSITGGCTCAPGFMGEVC-AVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEG 470
Query: 694 WGGLNCELARVQCPD-----------QCSGHGTYLPDTGLCSCDPNWMGPDCSVE----V 738
W GL+C L CP C+ P G CSC P W+G C +
Sbjct: 471 WQGLDCTL---PCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGT 527
Query: 739 CSVDCGTHGVC--------IGGACRCEEGWTGAACDQRVCHP-----------RCIEHGT 779
++C H C + G C C GWTG CD C P C G+
Sbjct: 528 FGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDS-TCPPGRWGPNCSVSCSCENGGS 586
Query: 780 C--KDGKCECREGWNGEHCTIDGCPDLCNGNG---RCTLGQNSWQ--------CVCQTGW 826
C +DG CEC G+ G C CP G+G C L +S + C C G+
Sbjct: 587 CSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGF 645
Query: 827 RGPGCN-----------VAMETSCADN 842
G CN A SCA+N
Sbjct: 646 SGALCNQVCAGGYFGQDCAQLCSCANN 672
Score = 76.3 bits (186), Expect = 4e-13
Identities = 69/227 (30%), Positives = 90/227 (39%), Gaps = 66/227 (29%)
Query: 658 CSAGYKGEHCEEVDCLDPTCSS---HGVCVNGE-CLCSPGWGGLNCELA------RVQCP 707
C GY E D P C+ HG CV+ + C C PGWGG +C C
Sbjct: 88 CCPGYY----ESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCS 143
Query: 708 DQCSGHGTYL--PDTGLCSCDPNWMGPDCSVEVCSVDCGTHG-------VCIGGA----- 753
++C L P TG C C + G C E+C+ GTHG C GA
Sbjct: 144 NRCQCQNGALCNPITGACVCAAGFRGWRCE-ELCAP--GTHGKGCQLPCQCRHGASCDPR 200
Query: 754 ---CRCEEGWTGAACDQRVCHP-----------RCIEHGTCK--DGKCECREGWN----- 792
C C G+TG C++ +C P C GTC G+C C GW
Sbjct: 201 AGECLCAPGYTGVYCEE-LCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCA 259
Query: 793 --------GEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC 831
G++C+ D CP C+ G+C + QC C G+ G C
Sbjct: 260 QPCPPGTFGQNCSQD-CP--CHHGGQC--DHVTGQCHCTAGYMGDRC 301
Score = 41.2 bits (95), Expect = 0.014
Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 28/114 (24%)
Query: 770 CHPRCIE---HGTC-KDGKCECREGWNGEHCTIDGCPD-----LCNGNGRCTLG----QN 816
C P C E HG C C C GW G C+ GC C+ +C G
Sbjct: 99 CIPLCTEECVHGRCVSPDTCHCEPGWGGPDCS-SGCDSDHWGPHCSNRCQCQNGALCNPI 157
Query: 817 SWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
+ CVC G+RG C E CA +G C L C++ C
Sbjct: 158 TGACVCAAGFRGWRC----EELCAPGTHGKG----------CQLPCQCRHGASC 197
Score = 32.7 bits (73), Expect = 5.1
Identities = 14/29 (48%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
Query: 580 CHGNGEC--VSGVCHCFPGFLGADCAKAA 606
C N C V+G C+C PGF G C +AA
Sbjct: 798 CMNNSTCDHVTGTCYCSPGFKGIRCDQAA 826
>gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains)
[Homo sapiens]
Length = 494
Score = 135 bits (340), Expect = 6e-31
Identities = 121/429 (28%), Positives = 147/429 (34%), Gaps = 159/429 (37%)
Query: 580 CHGNGECVSGVCHCF---PG-FLG--ADCAKAACPVL----CSGNGQYSKGTCQCYSGWK 629
CHG G C GVC C PG F G +C + C C+G+G+ G C+C GW
Sbjct: 63 CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122
Query: 630 GAECDVPMN--------------------------------------------------- 638
G C P N
Sbjct: 123 GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDD 182
Query: 639 -QCIDPS----CGGHGSCIDGNCVCSAGYKGEHCE----------EVDCLDP---TCSSH 680
+CID CGGHG C GNC C AG+ G+ CE + C P CS+
Sbjct: 183 RECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNR 242
Query: 681 GVCVNGECLC-----SPGWG---GLNCELARVQC--------PDQCSGHGTYLPDTGLCS 724
G CV GEC C + WG G CE C D CSGHG + G C
Sbjct: 243 GTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQC--NCGRCD 300
Query: 725 CDPNWMGPDC------------SVEVC----SVDCGTHGVCIGGACRCEE-------GWT 761
C W G C S+ C + C G C G C C G T
Sbjct: 301 CKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKT 360
Query: 762 GAACDQRVCHPR----CIEHGTCKDGKCECREGWNGEHC------------------TID 799
CD R C C HGTC G+C C GW G+ C + D
Sbjct: 361 -CECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESAD 419
Query: 800 GCPDLCNGNGRCTLGQNSWQCVCQT-GW--RGPGCNVAMETSCADNKDNEGDGLVDCLDP 856
G LC+G G C G +C+C W G C+ C D ++ DGL+ C
Sbjct: 420 GI--LCSGKGSCHCG----KCICSAEEWYISGEFCD------CDDRDCDKHDGLI-CTGN 466
Query: 857 DCCLQSACQ 865
C C+
Sbjct: 467 GICSCGNCE 475
Score = 115 bits (289), Expect = 5e-25
Identities = 88/296 (29%), Positives = 106/296 (35%), Gaps = 79/296 (26%)
Query: 580 CHGNGECVSGVCHCFPGFLGADC----------AKAACPV----LCSGNGQYSKGTCQCY 625
C G+G+C G C+C G+ G C +K C +CS G G C C+
Sbjct: 194 CGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCH 253
Query: 626 S-----GW---KGAECDVPMNQC-------IDPSCGGHGSCIDGNCVCSAGYKGEHCEEV 670
W G C+ C D C GHG C G C C AG+ G+ CE
Sbjct: 254 DVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHP 313
Query: 671 DCL---------------DPTCSSHGVCVNGECLCSPGWG----GLNCELARVQCPDQ-- 709
D CS G C G+C C P G CE +C D
Sbjct: 314 QSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDG 373
Query: 710 --CSGHGTYLPDTGLCSCDPNWMGPDC------------SVEVCS----VDCGTHGVCIG 751
C GHGT G C C+ W G C S +C + C G C
Sbjct: 374 VVCGGHGTC--SCGRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCHC 431
Query: 752 GACRCE-EGWTGAA----CDQRVCHPR----CIEHGTCKDGKCECREGWNGEHCTI 798
G C C E W + CD R C C +G C G CEC +GWNG C I
Sbjct: 432 GKCICSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEI 487
Score = 78.6 bits (192), Expect = 8e-14
Identities = 57/221 (25%), Positives = 84/221 (38%), Gaps = 55/221 (24%)
Query: 694 WGGLNCELARVQCPDQCSG----------HGTYLPDTGLCSC---DPN-WMGP--DCSVE 737
W G C L+R + +C HG D G+C C +P + GP +C
Sbjct: 35 WPGAACRLSRAESERRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECHEW 94
Query: 738 VCSV----DCGTHGVCIGGACRCEEGWTGAAC------------DQRVCHPR----CIEH 777
VC C HG C G C+C++GW G AC ++C C
Sbjct: 95 VCETYDGSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNA 154
Query: 778 GTCKDGKCECREG------------WNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTG 825
GTC G+C+C + C D ++C G+G+C G C C+ G
Sbjct: 155 GTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCG----NCYCKAG 210
Query: 826 WRGPGCNVAMETSCADNKD--NEGDGLVDCLDPDCCLQSAC 864
W G C + + ++K DG + C + C+ C
Sbjct: 211 WHGDKCEFQCDITPWESKRRCTSPDGKI-CSNRGTCVCGEC 250
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 134 bits (336), Expect = 2e-30
Identities = 96/295 (32%), Positives = 121/295 (41%), Gaps = 42/295 (14%)
Query: 578 RNCHGNGE-CVSGVCHCFPGFLGADCAKA----ACPVLCSGNGQY-----SKGTCQCYSG 627
+NC E C G C G G+D A +C +G+ +C C SG
Sbjct: 531 KNCSVPREPCPGGACRVIDG-CGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSG 589
Query: 628 WKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEV--DCLDPTCSSHG 681
+ G C ++ C+ C G+CID C C +G++GE C+ DCL C S G
Sbjct: 590 FTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRG 649
Query: 682 VC---VNG-ECLCSPGWGGLNCELARVQCPDQ-CSGHGTYLP--DTGLCSCDPNWMGPDC 734
C VN C C GW G C QC CS GT DT C+C P W G C
Sbjct: 650 RCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTC 709
Query: 735 SVEVCSV----DCGTHGVCIGG----ACRCEEGWTGAACDQRV--CHPR-CIEHGTCKDG 783
+V S C G C+G +C C +GW G C C+P C G C DG
Sbjct: 710 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDG 769
Query: 784 ----KCECREGWNGEHC--TIDGCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGC 831
+CEC G+ G C ID C C C N ++C C G GP C
Sbjct: 770 VNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 824
Score = 133 bits (334), Expect = 3e-30
Identities = 97/323 (30%), Positives = 119/323 (36%), Gaps = 66/323 (20%)
Query: 580 CHGNGECVSGV----CHCFPGFLGADCAKAA--CPVLCSGNGQYSKGT-----CQCYSGW 628
CH G C CHC GF G C C NG C C +
Sbjct: 469 CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF 528
Query: 629 KGAECDVPMNQC-------IDPS----------------CGGHGSCID---GN--CVCSA 660
G C VP C ID CG HG C+ GN C+C +
Sbjct: 529 GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDS 588
Query: 661 GYKGEHCEEV--DCLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC-PDQCSGH 713
G+ G +C E DCL C + G C++ C C GW G C+ C PD C
Sbjct: 589 GFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSR 648
Query: 714 GTY--LPDTGLCSCDPNWMGPDCSVEVCSVD---CGTHGVCIGGA----CRCEEGWTGAA 764
G L + C+CD W G C D C G C C C GW G+
Sbjct: 649 GRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGST 708
Query: 765 C---DQRVCHPR-CIEHGTCKDG----KCECREGWNGEHCT--IDGCPDL-CNGNGRCTL 813
C C P C+ GTC C CR+GW G CT + C L C G C
Sbjct: 709 CAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVD 768
Query: 814 GQNSWQCVCQTGWRGPGCNVAME 836
G N ++C C G+ GP C + ++
Sbjct: 769 GVNWFRCECAPGFAGPDCRINID 791
Score = 129 bits (323), Expect = 5e-29
Identities = 103/373 (27%), Positives = 141/373 (37%), Gaps = 81/373 (21%)
Query: 567 TVVLDSVQDCPRN-CHGNGECVSGV----CHCFPGFLGADCAKAACPVLCSGNGQYSKGT 621
T LD + +C N C G CV V C C ++GA C C G Q+ GT
Sbjct: 381 TCALD-IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVND--CRGQCQHG-GT 436
Query: 622 CQ---------CYSGWKGAECDVPMNQCIDPSCGGHGSCID----GNCVCSAGYKGEHCE 668
C+ C G+ G C++ ++C C G C D +C C G+ G CE
Sbjct: 437 CKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE 496
Query: 669 -EVDCLDPT-CSSHGVCVNGE----CLCSPGWGGLNCELARVQCPDQ------------- 709
+VD +P+ C + C N E C C +GG NC + R CP
Sbjct: 497 VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAG 556
Query: 710 -----------CSGHGTYLPDTG---LCSCDPNWMGPDC--SVEVC-SVDCGTHGVCIGG 752
C HG + G C CD + G C +++ C C G CI
Sbjct: 557 PGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDE 616
Query: 753 A----CRCEEGWTGAACDQRV-------CHPRCIEHGTCKDGKCECREGWNGEHC---TI 798
C C GW G CD CH R + D C C +GW G+ C
Sbjct: 617 VDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREF 676
Query: 799 DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC 858
C+ G C ++++C C GW+G C VA +SC N C++
Sbjct: 677 QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN---------PCVNGGT 727
Query: 859 CLQSACQNSLLCR 871
C+ S S +CR
Sbjct: 728 CVGSGASFSCICR 740
Score = 127 bits (319), Expect = 2e-28
Identities = 96/343 (27%), Positives = 127/343 (37%), Gaps = 92/343 (26%)
Query: 593 CFPGFLGADCAKAACPVLCSGNGQYSKGTCQ------CYSGWKGAECDVPMNQCIDPSCG 646
C + A C K P N + TC C GW G EC + C
Sbjct: 198 CDENYYSATCNKFCRP----RNDFFGHYTCDQYGNKACMDGWMGKECKEAV--CKQGCNL 251
Query: 647 GHGSC-IDGNCVCSAGYKGEHCEEV---------DCLDP--------------------- 675
HG C + G C CS G++G C+E C++P
Sbjct: 252 LHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYC 311
Query: 676 ----TCSSHGVCVNGE-----CLCSPGWGGLNCELARVQC-PDQCSGHGT--YLPDTGLC 723
C++ G C+N E C C G+ G NCE A C + C+ G+ +P C
Sbjct: 312 GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC 371
Query: 724 SCDPNWMGPDCSVEV---CSVDCGTHGVCI----GGACRCEEGWTGAAC--DQRVCHPRC 774
C W GP C++++ S C G C+ G C C E W GA C D C +C
Sbjct: 372 HCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQC 431
Query: 775 IEHGTCKD----GKCECREGWNGEHCTI--DGCPDL-CNGNGRCTLGQNSWQCVCQTGWR 827
GTCKD +C C G+ G HC + D C C+ G C + + C C G+
Sbjct: 432 QHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFS 491
Query: 828 GPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
GP C V D D C S C+N C
Sbjct: 492 GPLCEV---------------------DVDLCEPSPCRNGARC 513
Score = 127 bits (319), Expect = 2e-28
Identities = 112/416 (26%), Positives = 146/416 (35%), Gaps = 123/416 (29%)
Query: 580 CHGNGECVSGV-----CHCFPGFLGADCAKA--ACPVLCSGNGQY-----SKGTCQCYSG 627
C G C++ C C G+ G +C KA AC NG S C C SG
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
Query: 628 WKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE-EVDCLDPTCSSHGV 682
W G C + +++C C G+C+D C+C + G C+ +V+ C G
Sbjct: 377 WSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGT 436
Query: 683 C---VNG-ECLCSPGWGGLNCELARVQC---PDQCSGHGTYLPDTGLCSCDPNWMGPDCS 735
C VNG +C+C G+GG +CEL R +C P G L D C C + GP C
Sbjct: 437 CKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE 496
Query: 736 VEV------------------------CSVDCGTHGV------CIGGACR---------- 755
V+V C D G C GGACR
Sbjct: 497 VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAG 556
Query: 756 -----------------------------CEEGWTGAACDQRV---CHPRCIEHGTCKDG 783
C+ G+TG C + + C GTC D
Sbjct: 557 PGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDE 616
Query: 784 ----KCECREGWNGEHCTI---DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME 836
+C C GW GE C D PD C+ GRC N + C C GW+G C+ + E
Sbjct: 617 VDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH-SRE 675
Query: 837 TSCADNKDNEGDGLVD------CLDP-------------DCCLQSACQNSLLCRGS 873
C + G D C P CL + C N C GS
Sbjct: 676 FQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGS 731
Score = 122 bits (306), Expect = 5e-27
Identities = 86/295 (29%), Positives = 116/295 (39%), Gaps = 35/295 (11%)
Query: 576 CPRNC---HGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAE 632
C + C HG G V G C C G+ G C + C C C + W G
Sbjct: 245 CKQGCNLLHG-GCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLL 303
Query: 633 CDVPMNQC-IDPSCGGHGSCIDG-----NCVCSAGYKGEHCEEVD--CLDPTCSSHGVC- 683
CD +N C C G+CI+ C C GY G +CE+ + C C++ G C
Sbjct: 304 CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCH 363
Query: 684 ---VNGECLCSPGWGGLNCELARVQC-PDQCSGHGTYLP--DTGLCSCDPNWMGPDCSVE 737
EC C GW G C L +C + C+ GT + D C C W+G C ++
Sbjct: 364 EVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLD 423
Query: 738 V--CSVDCGTHGVC----IGGACRCEEGWTGAACD---QRVCHPRCIEHGTCKD----GK 784
V C C G C G C C G+ G C+ C G C+D
Sbjct: 424 VNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH 483
Query: 785 CECREGWNGEHCTIDG--C-PDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME 836
C C +G++G C +D C P C RC + + C C + G C+V E
Sbjct: 484 CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 538
Score = 102 bits (253), Expect = 7e-21
Identities = 78/269 (28%), Positives = 112/269 (41%), Gaps = 47/269 (17%)
Query: 647 GHGSCID-GNCVCSAGYKGEHCEEVDCLDPTCSSHGVC-VNGECLCSPGWGGLNCELARV 704
GH +C GN C G+ G+ C+E C HG C V GEC CS GW G C+
Sbjct: 219 GHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCD---- 274
Query: 705 QC-PDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGA---------- 753
+C P HG+ + + C+C+ NW G C ++ CG+H C G
Sbjct: 275 ECVPYPGCVHGSCV-EPWQCNCETNWGGLLCDKDLNY--CGSHHPCTNGGTCINAEPDQY 331
Query: 754 -CRCEEGWTGAACD--QRVCHPR-CIEHGTCKD----GKCECREGWNGEHCT--IDGC-P 802
C C +G++G C+ + C C G+C + +C C GW+G C ID C
Sbjct: 332 RCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECAS 391
Query: 803 DLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMET---------SCADNKDN------EG 847
+ C G C + ++C+C W G C + + +C D + G
Sbjct: 392 NPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRG 451
Query: 848 DGLVDC-LDPDCCLQSACQNSLLCRGSRD 875
G C L+ D C S C + LC D
Sbjct: 452 FGGRHCELERDECASSPCHSGGLCEDLAD 480
Score = 96.7 bits (239), Expect = 3e-19
Identities = 77/269 (28%), Positives = 106/269 (39%), Gaps = 45/269 (16%)
Query: 575 DC-PRNCHGNGECVSGV----CHCFPGFLGADC--AKAACPVLCSGNGQ--YSKGT---C 622
DC P CH G C V C C G+ G C + C NG Y G C
Sbjct: 639 DCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 698
Query: 623 QCYSGWKGAECDVPMNQ-CIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEV--DCLDP 675
C GWKG+ C V N C+ C G+C+ +C+C G++G C DC
Sbjct: 699 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPL 758
Query: 676 TCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDT---GLCSCDPN 728
C + G+CV+G C C+PG+ G +C + +C +G D CSC P
Sbjct: 759 PCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPG 818
Query: 729 WMGPDCSVEV-CSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCEC 787
GP C + C + G E D C C DG+ +C
Sbjct: 819 RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVE-------DCNSCR--------CLDGRRDC 863
Query: 788 REGWNG-EHCTIDGCPDLCNGNGRCTLGQ 815
+ W G + C + G P+ + +C LGQ
Sbjct: 864 SKVWCGWKPCLLAGQPEAL--SAQCPLGQ 890
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 134 bits (336), Expect = 2e-30
Identities = 96/295 (32%), Positives = 121/295 (41%), Gaps = 42/295 (14%)
Query: 578 RNCHGNGE-CVSGVCHCFPGFLGADCAKA----ACPVLCSGNGQY-----SKGTCQCYSG 627
+NC E C G C G G+D A +C +G+ +C C SG
Sbjct: 569 KNCSVPREPCPGGACRVIDG-CGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSG 627
Query: 628 WKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEV--DCLDPTCSSHG 681
+ G C ++ C+ C G+CID C C +G++GE C+ DCL C S G
Sbjct: 628 FTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRG 687
Query: 682 VC---VNG-ECLCSPGWGGLNCELARVQCPDQ-CSGHGTYLP--DTGLCSCDPNWMGPDC 734
C VN C C GW G C QC CS GT DT C+C P W G C
Sbjct: 688 RCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTC 747
Query: 735 SVEVCSV----DCGTHGVCIGG----ACRCEEGWTGAACDQRV--CHPR-CIEHGTCKDG 783
+V S C G C+G +C C +GW G C C+P C G C DG
Sbjct: 748 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDG 807
Query: 784 ----KCECREGWNGEHC--TIDGCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGC 831
+CEC G+ G C ID C C C N ++C C G GP C
Sbjct: 808 VNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 862
Score = 133 bits (334), Expect = 3e-30
Identities = 97/323 (30%), Positives = 119/323 (36%), Gaps = 66/323 (20%)
Query: 580 CHGNGECVSGV----CHCFPGFLGADCAKAA--CPVLCSGNGQYSKGT-----CQCYSGW 628
CH G C CHC GF G C C NG C C +
Sbjct: 507 CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF 566
Query: 629 KGAECDVPMNQC-------IDPS----------------CGGHGSCID---GN--CVCSA 660
G C VP C ID CG HG C+ GN C+C +
Sbjct: 567 GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDS 626
Query: 661 GYKGEHCEEV--DCLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQC-PDQCSGH 713
G+ G +C E DCL C + G C++ C C GW G C+ C PD C
Sbjct: 627 GFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSR 686
Query: 714 GTY--LPDTGLCSCDPNWMGPDCSVEVCSVD---CGTHGVCIGGA----CRCEEGWTGAA 764
G L + C+CD W G C D C G C C C GW G+
Sbjct: 687 GRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGST 746
Query: 765 C---DQRVCHPR-CIEHGTCKDG----KCECREGWNGEHCT--IDGCPDL-CNGNGRCTL 813
C C P C+ GTC C CR+GW G CT + C L C G C
Sbjct: 747 CAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVD 806
Query: 814 GQNSWQCVCQTGWRGPGCNVAME 836
G N ++C C G+ GP C + ++
Sbjct: 807 GVNWFRCECAPGFAGPDCRINID 829
Score = 131 bits (330), Expect = 8e-30
Identities = 98/329 (29%), Positives = 127/329 (38%), Gaps = 56/329 (17%)
Query: 576 CPRNC---HGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAE 632
C + C HG G V G C C G+ G C + C C C + W G
Sbjct: 245 CKQGCNLLHG-GCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLL 303
Query: 633 CDVPMNQC-IDPSCGGHGSCIDG-----NCVCSAGYKGEHCEEVD--CLDPTCSSHGVC- 683
CD +N C C G+CI+ C C GY G +CE+ + C C++ G C
Sbjct: 304 CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCH 363
Query: 684 ---VNGECLCSPGWGGLNCELARVQC-PDQCSGHGTYLP--DTGLCSCDPNWMGPDCSVE 737
EC C GW G C L +C + C+ GT + D C C W+G C ++
Sbjct: 364 EVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLD 423
Query: 738 VCSVD---CGTHGVC---IGG-ACRCEEGWTGAACDQRV--CHPRCIEHGTCKD----GK 784
+ C C IGG C C GW G C V C +C GTCKD +
Sbjct: 424 ANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQ 483
Query: 785 CECREGWNGEHCTI--DGCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCAD 841
C C G+ G HC + D C C+ G C + + C C G+ GP C V
Sbjct: 484 CVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-------- 535
Query: 842 NKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
D D C S C+N C
Sbjct: 536 -------------DVDLCEPSPCRNGARC 551
Score = 127 bits (318), Expect = 2e-28
Identities = 114/409 (27%), Positives = 150/409 (36%), Gaps = 115/409 (28%)
Query: 567 TVVLDSVQDCPRN-CHGNGECVSGV----CHCFPGFLGADCAKAA-------CPVLCSGN 614
T LD + +C N C G CV V C C ++GA C A C S
Sbjct: 381 TCALD-IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCK 439
Query: 615 GQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCID----GNCVCSAGYKGEHCE-- 668
C C GWKG C + +N C C G+C D CVC G+ G HCE
Sbjct: 440 NLIGGYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE 498
Query: 669 EVDCLDPTCSSHGVCVN----GECLCSPGWGGLNCELARVQC-PDQC-SGHGTY-LPDTG 721
+C C S G+C + C C G+ G CE+ C P C +G Y L
Sbjct: 499 RDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDY 558
Query: 722 LCSCDPNWMGPDCSV-------------EVCSVD-------------CGTHGVCI---GG 752
C+C ++ G +CSV + C D CG HG C+ GG
Sbjct: 559 YCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGG 618
Query: 753 --ACRCEEGWTGAACDQRV---CHPRCIEHGTCKDG----KCECREGWNGEHCTI---DG 800
+C C+ G+TG C + + C GTC D +C C GW GE C D
Sbjct: 619 NFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDC 678
Query: 801 CPDLCNGNGRCTLGQN--------------------------------------SWQCVC 822
PD C+ GRC N +++C C
Sbjct: 679 LPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCAC 738
Query: 823 QTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCR 871
GW+G C VA +SC N C++ C+ S S +CR
Sbjct: 739 PPGWKGSTCAVAKNSSCLPN---------PCVNGGTCVGSGASFSCICR 778
Score = 117 bits (292), Expect = 2e-25
Identities = 94/356 (26%), Positives = 139/356 (39%), Gaps = 66/356 (18%)
Query: 580 CHGNGECVSGV-----CHCFPGFLGADCAKA--ACPVLCSGNGQY-----SKGTCQCYSG 627
C G C++ C C G+ G +C KA AC NG S C C SG
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
Query: 628 WKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHC--EEVDCLDPTCSSHG 681
W G C + +++C C G+C+D C+C + G C + +C C +
Sbjct: 377 WSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAF 436
Query: 682 VCVN----GECLCSPGWGGLNCELARVQCPDQCSGHGTY--LPDTGLCSCDPNWMGPDCS 735
C N C C PGW G+NC + C QC GT L + C C + G C
Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCE 496
Query: 736 V---EVCSVDCGTHGVC----IGGACRCEEGWTGAAC--DQRVCHPR-CIEHGTC----K 781
+ E S C + G+C G C C +G++G C D +C P C C
Sbjct: 497 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 556
Query: 782 DGKCECREGWNGEHCT-------------IDGC-------------PDLCNGNGRC-TLG 814
D C C + + G++C+ IDGC +C +GRC +
Sbjct: 557 DYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQP 616
Query: 815 QNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
++ C+C +G+ G C+ ++ C G +D +D C + LC
Sbjct: 617 GGNFSCICDSGFTGTYCHENID-DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC 671
Score = 99.0 bits (245), Expect = 6e-20
Identities = 65/211 (30%), Positives = 94/211 (44%), Gaps = 31/211 (14%)
Query: 647 GHGSCID-GNCVCSAGYKGEHCEEVDCLDPTCSSHGVC-VNGECLCSPGWGGLNCELARV 704
GH +C GN C G+ G+ C+E C HG C V GEC CS GW G C+
Sbjct: 219 GHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCD---- 274
Query: 705 QC-PDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGA---------- 753
+C P HG+ + + C+C+ NW G C ++ CG+H C G
Sbjct: 275 ECVPYPGCVHGSCV-EPWQCNCETNWGGLLCDKDLNY--CGSHHPCTNGGTCINAEPDQY 331
Query: 754 -CRCEEGWTGAACD--QRVCHPR-CIEHGTCKD----GKCECREGWNGEHCT--IDGC-P 802
C C +G++G C+ + C C G+C + +C C GW+G C ID C
Sbjct: 332 RCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECAS 391
Query: 803 DLCNGNGRCTLGQNSWQCVCQTGWRGPGCNV 833
+ C G C + ++C+C W G C +
Sbjct: 392 NPCAAGGTCVDQVDGFECICPEQWVGATCQL 422
Score = 96.7 bits (239), Expect = 3e-19
Identities = 77/269 (28%), Positives = 106/269 (39%), Gaps = 45/269 (16%)
Query: 575 DC-PRNCHGNGECVSGV----CHCFPGFLGADC--AKAACPVLCSGNGQ--YSKGT---C 622
DC P CH G C V C C G+ G C + C NG Y G C
Sbjct: 677 DCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 736
Query: 623 QCYSGWKGAECDVPMNQ-CIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEV--DCLDP 675
C GWKG+ C V N C+ C G+C+ +C+C G++G C DC
Sbjct: 737 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPL 796
Query: 676 TCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDT---GLCSCDPN 728
C + G+CV+G C C+PG+ G +C + +C +G D CSC P
Sbjct: 797 PCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPG 856
Query: 729 WMGPDCSVEV-CSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCEC 787
GP C + C + G E D C C DG+ +C
Sbjct: 857 RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVE-------DCNSCR--------CLDGRRDC 901
Query: 788 REGWNG-EHCTIDGCPDLCNGNGRCTLGQ 815
+ W G + C + G P+ + +C LGQ
Sbjct: 902 SKVWCGWKPCLLAGQPEAL--SAQCPLGQ 928
Score = 85.1 bits (209), Expect = 9e-16
Identities = 45/127 (35%), Positives = 60/127 (47%), Gaps = 10/127 (7%)
Query: 724 SCDPNWMGPDCSVEVCSVDCGT-HGVC-IGGACRCEEGWTGAACDQRVCHPRCIEHGTC- 780
+C WMG +C VC C HG C + G CRC GW G CD+ V +P C+ HG+C
Sbjct: 230 ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCV-HGSCV 288
Query: 781 KDGKCECREGWNGEHCTID----GCPDLCNGNGRCTLGQ-NSWQCVCQTGWRGPGCNVAM 835
+ +C C W G C D G C G C + + ++C C G+ G C A
Sbjct: 289 EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKA- 347
Query: 836 ETSCADN 842
E +C N
Sbjct: 348 EHACTSN 354
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 132 bits (331), Expect = 6e-30
Identities = 64/166 (38%), Positives = 86/166 (51%), Gaps = 13/166 (7%)
Query: 643 PSCGGHG-----SCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGL 697
P C GHG SC C+C+ G+ G++C E C CSS GVCV+G+C+C + G
Sbjct: 173 PHCSGHGNFSFESC---GCICNEGWFGKNCSEPYC-PLGCSSRGVCVDGQCICDSEYSGD 228
Query: 698 NCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCE 757
+C + ++CP CS G + G C C+ + G DC C DC G C G C CE
Sbjct: 229 DC--SELRCPTDCSSRGLCVD--GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCE 284
Query: 758 EGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPD 803
EG+ G C QR C C G C++G C C EG+ G C+ P+
Sbjct: 285 EGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPE 330
Score = 129 bits (325), Expect = 3e-29
Identities = 63/160 (39%), Positives = 83/160 (51%), Gaps = 10/160 (6%)
Query: 675 PTCSSHG--VCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGP 732
P CS HG + C+C+ GW G NC + CP CS G + G C CD + G
Sbjct: 173 PHCSGHGNFSFESCGCICNEGWFGKNC--SEPYCPLGCSSRGVCVD--GQCICDSEYSGD 228
Query: 733 DCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWN 792
DCS C DC + G+C+ G C CEE +TG C + C C G C +G C C EG+
Sbjct: 229 DCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYV 288
Query: 793 GEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCN 832
GE C C + C+G G+C G CVC+ G++GP C+
Sbjct: 289 GEDCGQRQCLNACSGRGQCEEGL----CVCEEGYQGPDCS 324
Score = 122 bits (306), Expect = 5e-27
Identities = 66/179 (36%), Positives = 85/179 (47%), Gaps = 10/179 (5%)
Query: 570 LDSVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWK 629
LD + C + HGN S C C G+ G +C++ CP+ CS G G C C S +
Sbjct: 169 LDYIPHC--SGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYS 226
Query: 630 GAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECL 689
G +C C G C+DG CVC Y GE C E+ C CS G C NG CL
Sbjct: 227 GDDCS---ELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRC-PGDCSGKGRCANGTCL 282
Query: 690 CSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGV 748
C G+ G +C + QC + CSG G + GLC C+ + GPDCS D G+
Sbjct: 283 CEEGYVGEDC--GQRQCLNACSGRGQC--EEGLCVCEEGYQGPDCSAVAPPEDLRVAGI 337
Score = 115 bits (287), Expect = 8e-25
Identities = 52/153 (33%), Positives = 74/153 (48%), Gaps = 8/153 (5%)
Query: 710 CSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRV 769
CSGHG + ++ C C+ W G +CS C + C + GVC+ G C C+ ++G C +
Sbjct: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
Query: 770 CHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGP 829
C C G C DG+C C E + GE C CP C+G GRC G C+C+ G+ G
Sbjct: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANG----TCLCEEGYVGE 290
Query: 830 GCNVAMETSCADNKDNEGDGLVDCLD----PDC 858
C + + +GL C + PDC
Sbjct: 291 DCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDC 323
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 130 bits (328), Expect = 1e-29
Identities = 112/407 (27%), Positives = 148/407 (36%), Gaps = 114/407 (28%)
Query: 575 DCPRNCH-GNG---ECVSGVCHCFPGFLGADC------------AKAACPVLCSGNGQYS 618
DC + C NG + V+G C C PG+ GA C + CP G +
Sbjct: 190 DCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHV 249
Query: 619 KGTCQCYSGWKGAECDVP-------MNQCIDPSCGGHGSC--IDGNCVCSAGYKGEHCEE 669
G C C SGW G C P N + C G+C G C CS GY GE C++
Sbjct: 250 TGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQD 309
Query: 670 --------VDCLDP-TCSSHGVC--VNGECLCSPGWGGLNCE-------LARVQCPDQCS 711
V C + C + G C V+G CLC G+ G CE L ++C +C
Sbjct: 310 ECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCP 369
Query: 712 GH----GTYLPDTGLCSCDPNWMGPDCS------------VEVCSVDCGTHGVCIGGACR 755
H + P +G C+C P W G C+ ++CS G + G C
Sbjct: 370 CHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCT 429
Query: 756 CEEGWTGAACDQRV--------CHPR--CIEHGTCK--DGKCECREGWNGEHCTIDGCPD 803
C G+ G C C R C C DG C C+ GW+G C+I CP
Sbjct: 430 CAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSI-RCPS 488
Query: 804 -----------LCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME-----TSCADNKD-NE 846
C G C + C C GWRG C + + +CA+ D +
Sbjct: 489 GTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSH 546
Query: 847 GDGL---------------VDC--------LDPDCCLQSACQNSLLC 870
DG V C P+C L C+N C
Sbjct: 547 ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASC 593
Score = 129 bits (323), Expect = 5e-29
Identities = 106/376 (28%), Positives = 138/376 (36%), Gaps = 87/376 (23%)
Query: 580 CHGNGEC--VSGVCHCFPGFLGADCA------------KAACPVLCSGNGQYSKGTCQCY 625
C + C V G C C G+ G DC+ C L G GTC C
Sbjct: 458 CKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCA 517
Query: 626 SGWKGAECDVP-------MNQCIDPSCGGHGSC--IDGNCVCSAGYKGEHCEEVDCLD-- 674
GW+G +C++P +N C C G+C C G+ G HC+ V C +
Sbjct: 518 PGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSV-CAEGR 576
Query: 675 --PTCSSHGVCVNGE--------CLCSPGWGGLNCE----------LARVQCPDQCSGHG 714
P CS C NG C C+PG+ G C+ CP G
Sbjct: 577 WGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSG 636
Query: 715 TYLPDTGLCSCDPNWMGPDCSVEVCS-----------VDCGTHGVC--IGGACRCEEGWT 761
TGLC C P + G C+ EVC C +G C I +C+C GW
Sbjct: 637 PCHHITGLCDCLPGFTGALCN-EVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWI 695
Query: 762 GAACDQRV--CH--PRCIEHGTCK--------DGKCECREGWNGEHCTI--------DGC 801
G+ C Q H P CI C DG+C+C GW G +CT C
Sbjct: 696 GSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDC 755
Query: 802 PDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG-DGLVDCLDPDCC- 859
+C S QC C+TG+ G C E C G + DCL+ C
Sbjct: 756 ALICQCQNGADCDHISGQCTCRTGFMGRHC----EQKCPSGTYGYGCRQICDCLNNSTCD 811
Query: 860 -LQSACQNSLLCRGSR 874
+ C S +G+R
Sbjct: 812 HITGTCYCSPGWKGAR 827
Score = 121 bits (304), Expect = 8e-27
Identities = 94/336 (27%), Positives = 123/336 (36%), Gaps = 86/336 (25%)
Query: 580 CHGNGEC--VSGVCHCFPGFLGADCAKAA--------CPVLCS---GNGQY-SKGTCQCY 625
C G C + G C C PG+ G C C C +G + + G C+C
Sbjct: 501 CLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCL 560
Query: 626 SGWKGAECDVPMNQ------CIDPS-CGGHGSCI--DGNCVCSAGYKGEHCEEV------ 670
GW G CD + C P C SC DG C C+ G++G C+ +
Sbjct: 561 PGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFY 620
Query: 671 --DCLD--PTC-SSHGVC--VNGECLCSPGWGGLNCELARVQCPD-----------QCSG 712
C P C S G C + G C C PG+ G C CP C+
Sbjct: 621 GHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEV---CPSGRFGKNCAGICTCTN 677
Query: 713 HGTYLPDTGLCSCDPNWMGPDCS------------VEVCSVDCGTHGVCIGGACRCEEGW 760
+GT P C C P W+G DCS + C+ G G C+C GW
Sbjct: 678 NGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGW 737
Query: 761 TGAACDQR------------VCHPRCIEHGTCK--DGKCECREGWNGEHCTID------- 799
TG C QR +C +C C G+C CR G+ G HC
Sbjct: 738 TGLYCTQRCPLGFYGKDCALIC--QCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG 795
Query: 800 -GCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVA 834
GC +C+ T + C C GW+G C+ A
Sbjct: 796 YGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQA 831
Score = 118 bits (296), Expect = 7e-26
Identities = 98/373 (26%), Positives = 139/373 (37%), Gaps = 94/373 (25%)
Query: 573 VQDCPRNCHGNGECVS-GVCHCFPGFLGADCAKAA--------CPVLCS-GNGQYSK--- 619
V C C +G C++ C C PG+ G +C+ A C C NG
Sbjct: 106 VPHCADKCV-HGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPIT 164
Query: 620 GTCQCYSGWKGAECDVPM------NQCIDP-SCGGHGSC--IDGNCVCSAGYKGEHCEEV 670
G C C +G++G C+ N C C +C + G C C GY G CE++
Sbjct: 165 GACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDL 224
Query: 671 --------DCLDPT-CSSHGVC--VNGECLCSPGWGGLNCELARVQCPD----------- 708
C C + GVC V GEC C GW G C CP+
Sbjct: 225 CPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQP---CPEGRFGKNCSQEC 281
Query: 709 QCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVC---------------IGGA 753
QC GT TG C C P + G C E C V GT+GV + GA
Sbjct: 282 QCHNGGTCDAATGQCHCSPGYTGERCQDE-CPV--GTYGVLCAETCQCVNGGKCYHVSGA 338
Query: 754 CRCEEGWTGAACDQRVCHP-----RCIEHGTC----------KDGKCECREGWNGEHCTI 798
C CE G+ G C+ R+C +C + C G+C C+ GW+G +C
Sbjct: 339 CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNE 398
Query: 799 --------DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNV-----AMETSCADNKDN 845
+ C +C+ + +C C G++G C+ +C+
Sbjct: 399 TCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGC 458
Query: 846 EGDGLVDCLDPDC 858
+ D + +D C
Sbjct: 459 KNDAVCSPVDGSC 471
Score = 79.7 bits (195), Expect = 4e-14
Identities = 49/162 (30%), Positives = 68/162 (41%), Gaps = 40/162 (24%)
Query: 580 CHGNGEC--VSGVCHCFPGFLGADCAKAACPV--------LCS-GNGQYSK---GTCQCY 625
C NG C + C C+PG++G+DC++ P C+ NG + G C+C
Sbjct: 675 CTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCT 734
Query: 626 SGWKGAECD--VPM-----NQCIDPSCGGHGSC--IDGNCVCSAGYKGEHCEE------- 669
GW G C P+ + + C C I G C C G+ G HCE+
Sbjct: 735 PGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTY 794
Query: 670 -------VDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARV 704
DCL+ + H + G C CSPGW G C+ A V
Sbjct: 795 GYGCRQICDCLNNSTCDH---ITGTCYCSPGWKGARCDQAGV 833
Score = 55.8 bits (133), Expect = 6e-07
Identities = 44/160 (27%), Positives = 55/160 (34%), Gaps = 38/160 (23%)
Query: 735 SVEVCSVDCG---THGVCIG-GACRCEEGWTG----AACDQRVCHPRCIEHGTCKD---- 782
S E+C C HG CI C+CE GW G +ACD P C CK+
Sbjct: 101 SGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALC 160
Query: 783 ----GKCECREGWNGEHCTI--------DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPG 830
G C C G+ G C + C C T + +C C G+ G
Sbjct: 161 NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAF 220
Query: 831 CNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
C E C K P C + CQN +C
Sbjct: 221 C----EDLCPPGKHG----------PQCEQRCPCQNGGVC 246
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 129 bits (324), Expect = 4e-29
Identities = 106/393 (26%), Positives = 144/393 (36%), Gaps = 101/393 (25%)
Query: 577 PRNCHGNGECVS-GVCHCFPGFLGADCA------------KAACPVLCSGNGQYSKGTCQ 623
P C + CV G+C C PGF GA C+ + +CP G + + G CQ
Sbjct: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ 119
Query: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSC--IDGNCVCSAGYKGEHCEEVDCLDPTCSSHG 681
C + GA C+ P +CG HG C G C C G+ C C T ++
Sbjct: 120 CQADRWGARCEFPC------ACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAARC 172
Query: 682 VCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLP-DTGLCSCDPNWMGPDCSVEV-- 738
G C+C PGW G C +C+ HG+ D+G C+C P W GP+C +
Sbjct: 173 EQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC 225
Query: 739 ----------------------CSVDC--GTHGVCIGGAC-----------------RCE 757
C + C G+HGV +C CE
Sbjct: 226 VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCE 285
Query: 758 EGWTGAACDQ--------RVCHPRC--IEHGTCKD---GKCE-CREGWNGEHCTIDGCPD 803
GW G C Q C +C HG + G C+ C GW G C D CP
Sbjct: 286 PGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE-DPCPT 344
Query: 804 LCNGNG------RCTLGQN---SWQCVCQTGWRGPGCNVAMETSCADNKDNE----GDGL 850
G C G + CVC G+ GP CN + N + +GL
Sbjct: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL 404
Query: 851 VDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQG 883
+ C S +++ L GS PL ++ G
Sbjct: 405 CHPVSGSCQPGSGSRDTALIAGSLVPLLLLFLG 437
Score = 108 bits (269), Expect = 1e-22
Identities = 81/250 (32%), Positives = 99/250 (39%), Gaps = 43/250 (17%)
Query: 623 QCYSGW--KGAECDVPMNQCIDPSCGGHGSCID-GNCVCSAGYKGEHCEE--------VD 671
QC +GW K EC +P+ + D +C C+ G C C G+ G HC D
Sbjct: 40 QCCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
Query: 672 CLDPT-CSSHGVC--VNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPN 728
C + C HG C G C C G CE P C HG P TG+C C+P
Sbjct: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEF-----PCACGPHGRCDPATGVCHCEPG 153
Query: 729 WMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGT-CK--DGKC 785
W C GAC C+ GW G R C RC HG+ C+ G+C
Sbjct: 154 WWSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRC 208
Query: 786 ECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC---------NVAME 836
CR GW G C C + GRC+ S +C C G+RG C V
Sbjct: 209 ACRPGWWGPECQ-QQCECV---RGRCSAA--SGECTCPPGFRGARCELPCPAGSHGVQCA 262
Query: 837 TSCADNKDNE 846
SC K NE
Sbjct: 263 HSCGRCKHNE 272
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 129 bits (324), Expect = 4e-29
Identities = 106/393 (26%), Positives = 144/393 (36%), Gaps = 101/393 (25%)
Query: 577 PRNCHGNGECVS-GVCHCFPGFLGADCA------------KAACPVLCSGNGQYSKGTCQ 623
P C + CV G+C C PGF GA C+ + +CP G + + G CQ
Sbjct: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ 119
Query: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSC--IDGNCVCSAGYKGEHCEEVDCLDPTCSSHG 681
C + GA C+ P +CG HG C G C C G+ C C T ++
Sbjct: 120 CQADRWGARCEFPC------ACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAARC 172
Query: 682 VCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLP-DTGLCSCDPNWMGPDCSVEV-- 738
G C+C PGW G C +C+ HG+ D+G C+C P W GP+C +
Sbjct: 173 EQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC 225
Query: 739 ----------------------CSVDC--GTHGVCIGGAC-----------------RCE 757
C + C G+HGV +C CE
Sbjct: 226 VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCE 285
Query: 758 EGWTGAACDQ--------RVCHPRC--IEHGTCKD---GKCE-CREGWNGEHCTIDGCPD 803
GW G C Q C +C HG + G C+ C GW G C D CP
Sbjct: 286 PGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE-DPCPT 344
Query: 804 LCNGNG------RCTLGQN---SWQCVCQTGWRGPGCNVAMETSCADNKDNE----GDGL 850
G C G + CVC G+ GP CN + N + +GL
Sbjct: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL 404
Query: 851 VDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQG 883
+ C S +++ L GS PL ++ G
Sbjct: 405 CHPVSGSCQPGSGSRDTALIAGSLVPLLLLFLG 437
Score = 108 bits (269), Expect = 1e-22
Identities = 81/250 (32%), Positives = 99/250 (39%), Gaps = 43/250 (17%)
Query: 623 QCYSGW--KGAECDVPMNQCIDPSCGGHGSCID-GNCVCSAGYKGEHCEE--------VD 671
QC +GW K EC +P+ + D +C C+ G C C G+ G HC D
Sbjct: 40 QCCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
Query: 672 CLDPT-CSSHGVC--VNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPN 728
C + C HG C G C C G CE P C HG P TG+C C+P
Sbjct: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEF-----PCACGPHGRCDPATGVCHCEPG 153
Query: 729 WMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGT-CK--DGKC 785
W C GAC C+ GW G R C RC HG+ C+ G+C
Sbjct: 154 WWSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRC 208
Query: 786 ECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC---------NVAME 836
CR GW G C C + GRC+ S +C C G+RG C V
Sbjct: 209 ACRPGWWGPECQ-QQCECV---RGRCSAA--SGECTCPPGFRGARCELPCPAGSHGVQCA 262
Query: 837 TSCADNKDNE 846
SC K NE
Sbjct: 263 HSCGRCKHNE 272
>gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
Length = 379
Score = 129 bits (324), Expect = 4e-29
Identities = 63/157 (40%), Positives = 83/157 (52%), Gaps = 10/157 (6%)
Query: 645 CGGHGSCIDGN-CVCSAGYKGEHCEEVDCLDPTCSSHGVCVN-GECLCSPGWGGLNCELA 702
C G C + C C G+ G HCE+ C P C + G+CV G C+C PG+ G+NC+
Sbjct: 186 CRNGGFCNERRICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFYGVNCD-- 242
Query: 703 RVQCPDQCSGHGT-YLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG-GACRCEEGW 760
+ C C GT + P G C C P G C + C C G CIG C+C +G+
Sbjct: 243 KANCSTTCFNGGTCFYP--GKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGY 300
Query: 761 TGAACDQRVCHPRCIEHGTCKD-GKCECREGWNGEHC 796
G C + VC P C HGTC + KC+C+EGW+G HC
Sbjct: 301 QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337
Score = 95.5 bits (236), Expect = 6e-19
Identities = 56/175 (32%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 667 CEEVDCLDPTCSSHGVCVNGE-CLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSC 725
C++ +C C + G C C C G+ G +CE A C +C G + G C C
Sbjct: 177 CQQAEC-PGGCRNGGFCNERRICECPDGFHGPHCEKAL--CTPRCMNGGLCVTP-GFCIC 232
Query: 726 DPNWMGPDCSVEVCSVDCGTHGVCI-GGACRCEEGWTGAACDQRVCHPRCIEHGTC-KDG 783
P + G +C CS C G C G C C G G C+ C C G C
Sbjct: 233 PPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKS 292
Query: 784 KCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETS 838
KC+C +G+ G+ C+ C C +G C +C CQ GW G CN E S
Sbjct: 293 KCKCSKGYQGDLCSKPVCEPGCGAHGTC---HEPNKCQCQEGWHGRHCNKRYEAS 344
Score = 95.1 bits (235), Expect = 8e-19
Identities = 55/165 (33%), Positives = 71/165 (43%), Gaps = 11/165 (6%)
Query: 575 DCPRNCHGNGECVSG-VCHCFPGFLGADCAKAACPVLCSGNGQ-YSKGTCQCYSGWKGAE 632
+CP C G C +C C GF G C KA C C G + G C C G+ G
Sbjct: 181 ECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN 240
Query: 633 CDVPMNQCIDPSCGGHGSCI-DGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCV-NGECLC 690
CD +C G+C G C+C G +GE CE C P C + G C+ +C C
Sbjct: 241 CD---KANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKC 296
Query: 691 SPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCS 735
S G+ G C ++ C C HGT + C C W G C+
Sbjct: 297 SKGYQGDLC--SKPVCEPGCGAHGT-CHEPNKCQCQEGWHGRHCN 338
Score = 73.9 bits (180), Expect = 2e-12
Identities = 35/98 (35%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 575 DCPRNCHGNGECV-SGVCHCFPGFLGADCAKAACPVLCSGNGQ-YSKGTCQCYSGWKGAE 632
+C C G C G C C PG G C + CP C G+ K C+C G++G
Sbjct: 245 NCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDL 304
Query: 633 CDVPMNQCIDPSCGGHGSCIDGN-CVCSAGYKGEHCEE 669
C P+ +P CG HG+C + N C C G+ G HC +
Sbjct: 305 CSKPV---CEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
Score = 52.4 bits (124), Expect = 6e-06
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 573 VQDCPRNCHGNGECV-SGVCHCFPGFLGADCAKAACPVLCSGNGQ-YSKGTCQCYSGWKG 630
+ CP+ C G+C+ C C G+ G C+K C C +G + CQC GW G
Sbjct: 275 ISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHG 334
Query: 631 AECD 634
C+
Sbjct: 335 RHCN 338
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 129 bits (323), Expect = 5e-29
Identities = 104/348 (29%), Positives = 142/348 (40%), Gaps = 52/348 (14%)
Query: 573 VQDCP-RNCHGNGECVSGV----CHCFPGFLGADCA---KAACPVLCSGNGQYSKGT--- 621
V+DC +C G+C V C C PGF G+ C C NG T
Sbjct: 891 VKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRF 950
Query: 622 -CQCYSGWKGAECDVPMNQCIDPSCGGHGSCI---DG-NCVCSAGYKGEHCEEV--DCLD 674
C C + G C++ +N+C C +C+ DG NC+C+ GY G +CE +CL
Sbjct: 951 FCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLS 1010
Query: 675 PTCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHG--TYLPDTGLCSCDPN 728
C GVC++G C C G+ G +CE C HG T L + CSCD +
Sbjct: 1011 EPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDAD 1070
Query: 729 WMGPDCSVEV---CSVDCGTHGVCI----GGACRCEEGWTGAACDQRV---CHPR----- 773
C +++ S+ C G C G C C G+TGA C++ + P
Sbjct: 1071 GTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVI 1130
Query: 774 CIEHGTCKDGK-----CECREGWNGEHC--TIDGCPDL-CNGNGRCTLGQNSWQCVCQTG 825
C+ G C DG C C G++G+ C I+ C C C N + C CQ G
Sbjct: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPG 1190
Query: 826 WRGPGCNVAME---TSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
W G C +E SC E + CL + C LLC
Sbjct: 1191 WSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFM--TCSIGLLC 1236
Score = 122 bits (306), Expect = 5e-27
Identities = 99/380 (26%), Positives = 143/380 (37%), Gaps = 101/380 (26%)
Query: 573 VQDCPRN-CHGNGEC----VSGVCHCFPGFLGADCAKAA--CPVL-CSGNGQ----YSKG 620
+ DC N C N C +S C C + G C + + C + C N Y
Sbjct: 734 IDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSY 793
Query: 621 TCQCYSGWKGAECDVPMNQCIDPSCGGHGSC----------------------------- 651
C+C SGW G C +N+C C G C
Sbjct: 794 RCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC 853
Query: 652 ----------------IDGN--CVCSAGYKGEHCE--EVDCLDPTCSSHGVCV----NGE 687
+D N C+C ++G++CE DCL +C +G C N
Sbjct: 854 DLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFR 913
Query: 688 CLCSPGWGGLNCELARVQCPDQ-CSGHGTYLPDTG--LCSCDPNWMGPDCSVEV--CSVD 742
C+C PG+ G CE+ +C + C +GT + T C+C+P + GP C ++V C +
Sbjct: 914 CICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKIS 973
Query: 743 -CGTHGVCI----GGACRCEEGWTGAAC----DQRVCHPRCIEHGTCKDG----KCECRE 789
C C+ G C C G+TG C D+ + P C+ G C DG C+C+
Sbjct: 974 PCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEP-CLHDGVCIDGINHYTCDCKS 1032
Query: 790 GWNGEHCTIDGCPDLCNG--NGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG 847
G+ G HC + L N +GRCT N + C C C + +
Sbjct: 1033 GFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKIN----------- 1081
Query: 848 DGLVDCLDPDCCLQSACQNS 867
DC C + CQ S
Sbjct: 1082 ----DCTSIPCMNEGFCQKS 1097
Score = 115 bits (287), Expect = 8e-25
Identities = 86/318 (27%), Positives = 131/318 (41%), Gaps = 53/318 (16%)
Query: 579 NCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMN 638
NC G +C DC A+C + +C G+KG +C++ ++
Sbjct: 628 NCSGLQRYERNICEIDT----EDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDID 683
Query: 639 QCIDPSCGGHGSCID--GN----------------CVCSAGYKGEHCEE--VDCLDPTCS 678
+C C +CID GN C+C+ GY G CE+ DC+ C
Sbjct: 684 ECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACE 743
Query: 679 SHGVC----VNGECLCSPGWGGLNCELARVQCP-DQCSGHGTY--LPDTGLCSCDPNWMG 731
+ C ++ +C+C W G CE +C + C + T L + C C W G
Sbjct: 744 HNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTG 803
Query: 732 PDCSVEVCSVD---CGTHGVC----IGG--ACRCEEGWTGAACDQR-----VCHPRCIEH 777
+CS E+ D C G+C I G C C +TG C QR + H C +
Sbjct: 804 QNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNN 863
Query: 778 GTC-----KDGKCECREGWNGEHCTID--GCPDL-CNGNGRCTLGQNSWQCVCQTGWRGP 829
TC + C CRE + G++C ID C L C G C N+++C+C+ G+ G
Sbjct: 864 STCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGS 923
Query: 830 GCNVAMETSCADNKDNEG 847
C + + ++ N G
Sbjct: 924 LCEIEINECSSEPCKNNG 941
Score = 70.5 bits (171), Expect = 2e-11
Identities = 59/214 (27%), Positives = 82/214 (38%), Gaps = 34/214 (15%)
Query: 565 FNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVL--------CSGNGQ 616
F T + DC N +G C + + +P AD C + C G
Sbjct: 1035 FGTHCETNANDCLSNPCLHGRCTE-LINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGF 1093
Query: 617 YSKG----TCQCYSGWKGAECDVPMNQCIDPS-----CGGHGSCIDG-----NCVCSAGY 662
K TC C G+ GA C+ ++ C +P C G C+DG +C C G+
Sbjct: 1094 CQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF 1153
Query: 663 KGEHCEEV--DCLDPTCSSHGVC---VNGE-CLCSPGWGGLNCELARVQCPDQCSGHGTY 716
G+ CE +C C C +NG C C PGW G +CE P+ C
Sbjct: 1154 SGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCM 1213
Query: 717 LPDTG-LCSCDPNWM----GPDCSVEVCSVDCGT 745
+ G C C P +M G C E+ + C T
Sbjct: 1214 ENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLT 1247
Score = 67.0 bits (162), Expect = 2e-10
Identities = 54/228 (23%), Positives = 86/228 (37%), Gaps = 36/228 (15%)
Query: 645 CGGHGSCIDG------NCVCSAGYKGEHCEEVD-CLDPTCSSHGVCVNG---------EC 688
C GHG C+ +C C + G++C+E+D C C ++G C+N EC
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 689 LCSPGWGGLNCELARVQCPDQCSGHG---TYLPDTGLCSCDPNWMGPDCSVEV---CSVD 742
+C P + G NC QC HG ++ +C CD + GP C V S+
Sbjct: 243 VCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLL 302
Query: 743 CGTHGVCIGGAC----RCEEGWTGAACDQRVCHPRCI--EHGT-----CKDGKCECREGW 791
G+C + C +G + + V + ++GT D C C +
Sbjct: 303 FWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIF 362
Query: 792 NGEHCTI--DGCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME 836
C C N C + + C C +G+ C A++
Sbjct: 363 TDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAID 410
Score = 52.4 bits (124), Expect = 6e-06
Identities = 73/290 (25%), Positives = 98/290 (33%), Gaps = 70/290 (24%)
Query: 580 CHGNGECVSGV------CHCFPGFLGADCAKA-ACPVL-CSGNG---------QYSKGTC 622
C G+G+C+S CHC P F G C + AC C NG C
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 623 QCYSGWKGAECDVPMNQCIDPSCGGHGSC--IDGN---CVCSAGYKGEHCE--EVDCLDP 675
C+ + G C + QC P HG+C I N C C + G CE C+
Sbjct: 243 VCHPPFTGKNCSEIIGQC-QPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
Query: 676 TCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCS 735
G+C N + +CP S D S P G DC
Sbjct: 302 LFWKRGICPNSSSAYT------------YECPKGSSSQNGE-TDVSEFSLVPCQNGTDC- 347
Query: 736 VEVCSVDCGTHGVCIGGACRCEEGWTGAACD--QRVCHPRCI-EHGTC----KDGKCECR 788
+ +CI C +T C Q C + + TC KD C C
Sbjct: 348 -----IKISNDVMCI-----CSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCI 397
Query: 789 EGWNGEHC--TIDGCPDL---CNGNGRC--TLGQNSWQCVCQTGWRGPGC 831
G+ ++C ID C L C C +G+ + C+ PGC
Sbjct: 398 SGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCI-------PGC 440
Score = 43.9 bits (102), Expect = 0.002
Identities = 57/254 (22%), Positives = 88/254 (34%), Gaps = 55/254 (21%)
Query: 580 CHGNGECVSG---------VCHCFPGFLGADCAK--AACPVLCSGNGQYSKGT-----CQ 623
C NG C++ C C P F G +C++ C +G S T C+
Sbjct: 222 CKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICE 281
Query: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCV----CSAGYKGEHCEEVDCLDPTCSS 679
C + G C+V C+ G C + + C G ++ E D + S
Sbjct: 282 CDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGE----TDVSEFS 337
Query: 680 HGVCVNGE----------CLCSPGWGGLNCELARVQC---PDQCSGHGTYLPDTGLCSCD 726
C NG C+CSP + L C+ + C P + + CSC
Sbjct: 338 LVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCI 397
Query: 727 PNWMGPDC--SVEVC---SVDCGTHGVCIGGACR----CEEGWTGAAC---------DQR 768
+ +C +++ C S++C C R C G T C Q
Sbjct: 398 SGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQH 457
Query: 769 VCHPRCIEHGTCKD 782
+C+ HG C+D
Sbjct: 458 LCYCGVTFHGICQD 471
Score = 42.0 bits (97), Expect = 0.008
Identities = 34/116 (29%), Positives = 46/116 (39%), Gaps = 28/116 (24%)
Query: 581 HGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQ--YSKGT---CQCYSGWKGAECDV 635
H N G CH P C ++ GNG GT C C +GWKG+ C
Sbjct: 2599 HPNAGRSVGQCHASP-----------CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTE 2647
Query: 636 PMNQCIDPS------CGGHGSCID----GNCVCSAGYKGEHCEE-VDCLDPTCSSH 680
++ C DP C +CI C C G G +CE+ + DP+ S+
Sbjct: 2648 TVSTC-DPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSN 2702
Score = 41.2 bits (95), Expect = 0.014
Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 10/81 (12%)
Query: 774 CIEHGTCKDGKCECREGWNGEHCT--IDGC------PDLCNGNGRCTLGQNSWQCVCQTG 825
CIE GT C C GW G CT + C P C+ C + + C C G
Sbjct: 2625 CIESGTSV--YCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
Query: 826 WRGPGCNVAMETSCADNKDNE 846
G C A+ S + NE
Sbjct: 2683 TTGIYCEQALSISDPSFRSNE 2703
Score = 39.3 bits (90), Expect = 0.054
Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 11/76 (14%)
Query: 633 CDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGE- 687
C VP C C +G+CI N C C Y G+ C+ C + C + CV
Sbjct: 2334 CHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSG 2391
Query: 688 ----CLCSPGWGGLNC 699
CLC G G C
Sbjct: 2392 TDIVCLCPYGRSGPLC 2407
Score = 39.3 bits (90), Expect = 0.054
Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 17/87 (19%)
Query: 630 GAECDVPMNQCIDPSCGGHGSCIDG----------NCVCSAGYKGEHCEE-VDCLDPTCS 678
GA+ + C +CG + +C +G +C C + G C + V CL+ C
Sbjct: 2864 GAKGGSNVGDCDGTACG-YNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL 2922
Query: 679 SHGVCVNGE-----CLCSPGWGGLNCE 700
+C+ + CLC+ GW G CE
Sbjct: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 38.5 bits (88), Expect = 0.093
Identities = 41/169 (24%), Positives = 59/169 (34%), Gaps = 29/169 (17%)
Query: 723 CSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRC-IEHGTCK 781
CSC +++G C V V G H + + G C + QR C I+ CK
Sbjct: 590 CSCSLSYIGRLCVVNV-DYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCK 648
Query: 782 DGKCE---------------CREGWNGEHCTID---GCPDLCNGNGRCTLGQNSWQCVCQ 823
C+ C G+ G C ID C C ++ C C
Sbjct: 649 SASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCV 708
Query: 824 TGWRGPGCNVAMETSCADNKDNEGDGLVDC-LDPDCCLQSACQNSLLCR 871
P V SC N G + C D D C+ +AC+++ C+
Sbjct: 709 -----PPFKVVDGFSCLCNPGYVG---IRCEQDIDDCILNACEHNSTCK 749
Score = 38.5 bits (88), Expect = 0.093
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 7/75 (9%)
Query: 667 CEEVDCLDPTCSSHGVC-VNG---ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGL 722
C+ C TC + G C VNG C C P W G C + + C +PD
Sbjct: 2874 CDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSF 2933
Query: 723 ---CSCDPNWMGPDC 734
C C W+G C
Sbjct: 2934 SYSCLCTLGWVGRYC 2948
Score = 38.5 bits (88), Expect = 0.093
Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 762 GAACDQRVCHP--RCIEHGTCKDGKCECREGWNGEHC--TIDGCPDLCNGNGRCTLGQN- 816
G AC C C +GT C C W G C ++ +LC C Q+
Sbjct: 2876 GTACGYNTCRNGGECTVNGTTFS--CRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSF 2933
Query: 817 SWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPD 857
S+ C+C GW G C S A G+ + +DP+
Sbjct: 2934 SYSCLCTLGWVGRYCENKTSFSTAKFM---GNSYIKYIDPN 2971
Score = 37.7 bits (86), Expect = 0.16
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 11/78 (14%)
Query: 601 DCAKAACPV-LCSGNGQYS-KGT---CQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG- 654
DC AC C G+ + GT C+C W G C+ ++ C++ C CI
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQ 2931
Query: 655 ----NCVCSAGYKGEHCE 668
+C+C+ G+ G +CE
Sbjct: 2932 SFSYSCLCTLGWVGRYCE 2949
Score = 37.4 bits (85), Expect = 0.21
Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 12/76 (15%)
Query: 733 DCSVEVCSVD-CGTHGVC-IGG---ACRCEEGWTGAACDQRV--CHPRCIEHGTCKDGK- 784
DC C + C G C + G +CRC W G C+Q V + C+ C +
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQS 2932
Query: 785 ----CECREGWNGEHC 796
C C GW G +C
Sbjct: 2933 FSYSCLCTLGWVGRYC 2948
Score = 36.6 bits (83), Expect = 0.35
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 11/67 (16%)
Query: 709 QCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVD--CGTHGVCI-----GGACRCEEGWT 761
+C+ +GT T C C P+W G C+ V ++ C +CI +C C GW
Sbjct: 2889 ECTVNGT----TFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWV 2944
Query: 762 GAACDQR 768
G C+ +
Sbjct: 2945 GRYCENK 2951
Score = 36.2 bits (82), Expect = 0.46
Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 22/94 (23%)
Query: 686 GECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVD--- 742
G+C SP C L + C GT + C+C W G C+ V + D
Sbjct: 2607 GQCHASP------CSLMKCGNGGTCIESGTSV----YCNCTTGWKGSFCTETVSTCDPEH 2656
Query: 743 -----CGTHGVCI----GGACRCEEGWTGAACDQ 767
C CI G C C G TG C+Q
Sbjct: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 35.8 bits (81), Expect = 0.60
Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 6/71 (8%)
Query: 771 HPRCIEHGTCKDGK----CECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQ--CVCQT 824
H C +GTC CEC ++G+ C C + GNG + ++ C+C
Sbjct: 2341 HHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPY 2400
Query: 825 GWRGPGCNVAM 835
G GP C A+
Sbjct: 2401 GRSGPLCTDAI 2411
Score = 33.5 bits (75), Expect = 3.0
Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 3/54 (5%)
Query: 790 GWNGEHCTIDGCP-DLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADN 842
G N C C + C G CT+ ++ C C W G CN SC +N
Sbjct: 2868 GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN--QSVSCLNN 2919
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 127 bits (318), Expect = 2e-28
Identities = 81/284 (28%), Positives = 115/284 (40%), Gaps = 39/284 (13%)
Query: 591 CHCFPGFLGADCAK-----AACPVLCSGNGQYSKGT--CQCYSGWKGAECDVPMNQCIDP 643
C C PGF G C + + P G Q G C+C G++G C +++C+
Sbjct: 537 CICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 644 SCGGHGSCIDGN----CVCSAGYKGEHCEEVDCLDPTCSSHGVCVN----GECLCSPGWG 695
C SC+D C+C +G+ G+ CE C C +C + CLC G
Sbjct: 597 PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSP 656
Query: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEV---CSVDCGTHGVCI-- 750
G D C+ H + + C CD W GP+C E+ S C G C
Sbjct: 657 GC------APPEDNCTCHHGHCQRSS-CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 751 --GGACRCEEGWTGAACDQRV--CHPR-CIEHGTCKDGK----CECREGWNGEHC--TID 799
G C C G+TG C + + CH C+ G+C C C G C + D
Sbjct: 710 PSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTD 769
Query: 800 GCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADN 842
C C G C ++ C+C G++GP C + SCAD+
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADS 813
Score = 120 bits (301), Expect = 2e-26
Identities = 101/370 (27%), Positives = 139/370 (37%), Gaps = 82/370 (22%)
Query: 571 DSVQDCPRN-CHGNGECVSGV----CHCFPGFLGA-------DCAKAACPVLCSGNGQYS 618
+ + +C + C G+C C C PGF G +C CPV S
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPG 609
Query: 619 KGTCQCYSGWKGAECDVPM---NQCI-------------------DPSCGG--------H 648
C C SG+ G C+VP+ N C P C H
Sbjct: 610 AFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH 669
Query: 649 GSCIDGNCVCSAGYKGEHCEEV--DCLDPTCSSHGVCV----NGECLCSPGWGGLNCELA 702
G C +CVC G+ G CE C+ C+ G C C C G+ G C
Sbjct: 670 GHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEE 729
Query: 703 RVQCPD-QCSGHGTYLPDTG--LCSCDPNWMGPDC--SVEVC-SVDCGTHGVCIGG---- 752
C C G+ P G C+C P+ GP C S + C S C G C+
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 753 ACRCEEGWTGAACDQRVCHPRCIE-----HGTCKDG----KCECREGWNGEHCT--IDGC 801
+C C G+ G C+ ++ P C + TC+D +C C G+ G C +D C
Sbjct: 790 SCLCAMGFQGPRCEGKL-RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLC 848
Query: 802 PDL-CNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCL 860
C N C S+ C+C GW GP CN+ + +SC ++G +D +
Sbjct: 849 AQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPL-SSCQKAALSQG---ID-------V 897
Query: 861 QSACQNSLLC 870
S C N LC
Sbjct: 898 SSLCHNGGLC 907
Score = 120 bits (300), Expect = 2e-26
Identities = 100/362 (27%), Positives = 138/362 (38%), Gaps = 67/362 (18%)
Query: 580 CHGNGECVSGV----CHCFPGFLGADCAKAA--C----PVLCSGNG--QYSKGT--CQCY 625
C G C G+ C C + G DC++ C P C G Q S G+ C C
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 626 SGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEVD-CL------D 674
SGW G C+ ++ CI +C +CID +C+C G G C D CL D
Sbjct: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGD 404
Query: 675 PTCSSHGVCVNGECLCSPGWGGLNCE------LARVQCPDQCSGHGTYL--PDTGLCSCD 726
CS++ + + CLC PG+ G C L Q P C G+ L P + C C
Sbjct: 405 AQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
Query: 727 PNWMGPDCSV---EVCSVDCGTHGVCIG----GACRCEEGWTGAACD---QRVCHPRCIE 776
P + G C E S C C+ C C G G C+ C+
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLN 524
Query: 777 HGTCKD----GKCECREGWNGEHC--TIDGC-PDLCNGNGRCTLGQNSWQCVCQTGWRGP 829
H C D +C C G++G C ID C C G+C ++ C C G+ GP
Sbjct: 525 HADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGP 584
Query: 830 GCNVAMETSCADNKDNEGDGLVD------CLDPD----------CCLQSACQNSLLCRGS 873
C ++ C + G +D CL P C + CQ +C+
Sbjct: 585 RCQTEVD-ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQ 643
Query: 874 RD 875
+D
Sbjct: 644 KD 645
Score = 119 bits (299), Expect = 3e-26
Identities = 105/359 (29%), Positives = 128/359 (35%), Gaps = 91/359 (25%)
Query: 577 PRNCHGNGECVS-----GVCHCFPGFLGADCA---KAACPVLCSGNGQYS---------- 618
P C G C+S G C C PGFLG C LC G
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLP 91
Query: 619 --------KGTCQCYSGWKGAECDVPMNQCIDPS-CGGHGSC---IDG--NCVCSAGYKG 664
C C G+ G C + PS C G C G C C G+ G
Sbjct: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
Query: 665 EHCEEVD-CLDPTCSSHGVCV----NGECLCSPGWGGLNCELARVQ-------CPDQCSG 712
E C+ D C C + GVC+ +C C PG+ G CE + CP S
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSC 211
Query: 713 HGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR-------------CEEG 759
H T + C C GP C E+ + C G GG C+ C G
Sbjct: 212 HNTL--GSFQCLCPVGQEGPRC--ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 760 WTGAAC----DQRVCHPRCIEHGTCKDG----KCECREGWNGEHCT--IDGC----PDLC 805
+ G C D V H +C GTC+DG C C E W G C+ +D C P C
Sbjct: 268 FIGPDCEVNPDNCVSH-QCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHC 326
Query: 806 NGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSAC 864
G C S+ CVC +GW G TSC +N D DC+ C S C
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGG--------TSCEENLD-------DCIAATCAPGSTC 370
Score = 108 bits (270), Expect = 7e-23
Identities = 94/318 (29%), Positives = 115/318 (36%), Gaps = 75/318 (23%)
Query: 580 CHGNGECV----SGVCHCFPGFLGA-------DCAKAACPVLCSGNGQYSKGTCQCYSGW 628
CH G CV S CHC PGF G+ C C + Q S CQC G+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 629 KGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE-EVD-CLDPTC----- 677
G C ++ C C HG+C +C C G+ G CE +VD CLD C
Sbjct: 961 DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020
Query: 678 -SSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSV 736
+ H + C C PG G CE+ C Q HG G C
Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHG------GTCE------------ 1062
Query: 737 EVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEH-----GTC----KDG---K 784
T G +G C C +G+ G C R P C H G C K G +
Sbjct: 1063 -------ATAGSPLGFICHCPKGFEGPTCSHRA--PSCGFHHCHHGGLCLPSPKPGFPPR 1113
Query: 785 CECREGWNGEHCTI----DGC--PDLCNGNGRCT----LGQNSWQCVCQTGWRGPGCNVA 834
C C G+ G C GC P C NG C+ LG ++C C GP C
Sbjct: 1114 CACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKP 1173
Query: 835 METSCADNKDNEGDGLVD 852
C + GDG D
Sbjct: 1174 GAKGC---EGRSGDGACD 1188
Score = 99.0 bits (245), Expect = 6e-20
Identities = 85/349 (24%), Positives = 130/349 (37%), Gaps = 92/349 (26%)
Query: 580 CHGNGECV---SGV-CHCFPGFLGADCAK--AAC---PVLCSGNGQYSKGT--CQCYSGW 628
C G C SG C C G+ G C++ AC P L G+ S G C C
Sbjct: 700 CAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH 759
Query: 629 KGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE---EVDCLDPTCSSHG 681
G +C + C+ C G+C++ +C+C+ G++G CE C D C +
Sbjct: 760 TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 682 VCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGL---CSCDPNWMGPDC 734
C + CLC G+ G +C+ C + ++ TG C C W GP C
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 735 SVEVCSVD-------------CGTHGVCIGGA----CRCEEGWTGAACDQRV--CHPRCI 775
++ + S C G+C+ C C G+ G+ C V C R
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPC 939
Query: 776 EHG-TCKDGK----CECREGWNGEHCT--IDGCPDL-CNGNGRCT--------------- 812
++G TC C+C G++G++C+ +D C C+ +G CT
Sbjct: 940 QNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFV 999
Query: 813 -----------LGQ--------------NSWQCVCQTGWRGPGCNVAME 836
L Q N++ C C G G C V ++
Sbjct: 1000 GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEID 1048
Score = 96.3 bits (238), Expect = 4e-19
Identities = 80/316 (25%), Positives = 113/316 (35%), Gaps = 49/316 (15%)
Query: 580 CHGNGECVSGVCHCFPGFLGADCAK---AACPVLCSGNG----QYSKGTCQCYSGWKGAE 632
CH +G C C C G+ G +C C+ G Q S C C +G+ G
Sbjct: 667 CH-HGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPT 725
Query: 633 CDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHCEEVD--CLDPTCSSHGVCVNG 686
C M C C GSC C C + G C+ C+ C + G CVN
Sbjct: 726 CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785
Query: 687 ----ECLCSPGWGGLNCE-LARVQCPDQ-CSGHGTYL--PDTGLCSCDPNWMGPDCS--V 736
CLC+ G+ G CE R C D C T P C C + G C +
Sbjct: 786 PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 845
Query: 737 EVCSVD-CGTHGVCIGGA----CRCEEGWTGAACDQRVCHPR-------------CIEHG 778
++C+ C + C+ C C +GWTG C+ + + C G
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 779 TCKDGK----CECREGWNGEHCT--IDGCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGC 831
C D C C G+ G C ++ C C C + + C C G+ G C
Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965
Query: 832 NVAMETSCADNKDNEG 847
+ ++ + N G
Sbjct: 966 SKELDACQSQPCHNHG 981
Score = 88.2 bits (217), Expect = 1e-16
Identities = 77/288 (26%), Positives = 107/288 (37%), Gaps = 83/288 (28%)
Query: 645 CGGHGSCID-----GNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGE------------ 687
C G+C+ G C C+ G+ GE C+ D C + +C NG
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPD----PCQNAQLCQNGGSCQALLPAPLGL 90
Query: 688 ------------CLCSPGWGGLNCELARVQ--CPDQ-CSGHGT-YLPDTGL--CSCDPNW 729
C C PG+ G C+ A+++ CP CS G ++ +G CSC P W
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQ-AKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGW 149
Query: 730 MGPDCSV-EVCSVD-CGTHGVCIGG----ACRCEEGWTGAACDQRV---------CHPRC 774
G C + + CS + C GVC+ C C G+ G AC++ V C
Sbjct: 150 TGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGT 209
Query: 775 IEHGTCKDGKCECREGWNGEHCTIDG--CPDL-CNGNGRCTL----GQNSWQCVCQTGWR 827
H T +C C G G C + CP C+ G C L C+C G+
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
Query: 828 GPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRD 875
GP C V +PD C+ CQN C+ D
Sbjct: 270 GPDCEV---------------------NPDNCVSHQCQNGGTCQDGLD 296
Score = 69.3 bits (168), Expect = 5e-11
Identities = 92/350 (26%), Positives = 117/350 (33%), Gaps = 122/350 (34%)
Query: 570 LDSVQDCPRNCHGNGECVSGV----CHCFPGFLGADC---------------AKAACPVL 610
LD+ Q P CH +G C C C PGF+G C AAC L
Sbjct: 969 LDACQSQP--CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSL 1026
Query: 611 CSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSC-------IDGNCVCSAGYK 663
N Y CQC G G C+V ++ C C G+C + C C G++
Sbjct: 1027 A--NAFY----CQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE 1080
Query: 664 GEHCEEVDCLDPTCSSH-----GVCVNG-------ECLCSPGWGGLNCEL--ARVQC--P 707
G C P+C H G+C+ C C G+GG +C A C P
Sbjct: 1081 GPTCSH---RAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
Query: 708 DQCSGHGTYLPDTGL------CSCDP---------------------------------N 728
C +G+ TGL CSC N
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Query: 729 WMGPDCSVEVCS--VDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDG-KC 785
W G DCS+ V C +H C W Q CHP+C DG C
Sbjct: 1198 WDGGDCSLGVPDPWKGCPSHSRC----------WLLFRDGQ--CHPQCDSEECLFDGYDC 1245
Query: 786 E----CREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC 831
E C ++ C D + NG C G N+ +C GW G C
Sbjct: 1246 ETPPACTPAYD------QYCHDHFH-NGHCEKGCNTAEC----GWDGGDC 1284
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 126 bits (316), Expect = 3e-28
Identities = 100/359 (27%), Positives = 126/359 (35%), Gaps = 66/359 (18%)
Query: 578 RNCHGNGECV--------SGVCHCFPGFLGADC---AKAACPVLCSGNGQYSKGT----C 622
R C G+C+ S C C GF G C C G + G C
Sbjct: 276 RPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRC 335
Query: 623 QCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHCEEV--DCLDPT 676
QC +G+ G C+ + C C G C N CVC AGY G CE DC
Sbjct: 336 QCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDP 395
Query: 677 CSSHGVCV----NGECLCSPGWGGLNCELARVQCPDQC------SGHGTYLPDTG-LCSC 725
C + G CV N CLC+ + GL CE PD C +G D G +C C
Sbjct: 396 CLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCEC 455
Query: 726 DPNWMGPDCSVEVCS-VDCGTHGVCIGG---ACRCEEGWTGAACDQRVCHPRCIEHGTCK 781
+MG DC V +C G C+G C+C G+ G C+ + C + C
Sbjct: 456 PEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCP 515
Query: 782 DGK----------CECREGWNGEHCTIDGCP-DLCNGNGRCTLGQNSWQCVCQTGWRGPG 830
DG C C N H C D C G C +S+ C C G+ G
Sbjct: 516 DGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKH 575
Query: 831 CNVAMETSCADN--------KDNEGDGLVDCL-----------DPDCCLQSACQNSLLC 870
C A C+ K+ G+ C PD C C N C
Sbjct: 576 CEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC 634
Score = 104 bits (260), Expect = 1e-21
Identities = 94/344 (27%), Positives = 121/344 (35%), Gaps = 78/344 (22%)
Query: 578 RNCHGNGECV----SGVCHCFPGFLGADC---AKAACPVLCSGNGQ----YSKGTCQCYS 626
+ C G+C S VC C G+ GA C P C G TC C
Sbjct: 356 KECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAE 415
Query: 627 GWKGAECD-----VPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHCEEVDCLDPTC 677
+KG C+ VP + C+ C G+C+D + C C G+ G C E D C
Sbjct: 416 PFKGLRCETGDHPVP-DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCEC 474
Query: 678 SSHGVCVNGE---CLCSPGWGGLNCEL--------ARVQCPD--QCSGHGTYLPDTGLCS 724
+ G C+ C C G+ GL CE QCPD C HG + LC
Sbjct: 475 RNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG----GSYLCV 530
Query: 725 CDPNWMGPDCSVEVCSVD-CGTHGVCIGG----ACRCEEGWTGAACDQRVCH----PRCI 775
C + C D C G C C C G+ G C++ H C
Sbjct: 531 CHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCR 590
Query: 776 EHGTCKDG----KCECREGWNGEHCTIDGCPDL-----CNGNGRCTLGQNSWQCVCQTGW 826
GTCK+ C C + G HC I G PD C+ G C ++C C G+
Sbjct: 591 NGGTCKEAGGEYHCSCPYRFTGRHCEI-GKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF 649
Query: 827 RGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLC 870
G C +A P C +S C N C
Sbjct: 650 SGRHCEIA---------------------PSPCFRSPCVNGGTC 672
Score = 99.0 bits (245), Expect = 6e-20
Identities = 87/323 (26%), Positives = 122/323 (37%), Gaps = 69/323 (21%)
Query: 580 CHGNGECV----SGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQ---------CYS 626
C G C S C C GF G C KA P LCS + GTC+ C
Sbjct: 550 CFNGGSCDAHDDSYTCECPRGFHGKHCEKAR-PHLCSSGPCRNGGTCKEAGGEYHCSCPY 608
Query: 627 GWKGAECDVPM-NQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEEVD--CLDPTCSS 679
+ G C++ + C C G+C C C G+ G HCE C C +
Sbjct: 609 RFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVN 668
Query: 680 HGVCVNGE----CLCSPGWGGLNCELARVQC--PDQCSG-----HGTYLPDTGLCSCDPN 728
G C + + C C G+ G C+ A V C P++ +GT L L +CD
Sbjct: 669 GGTCEDRDTDFFCHCQAGYMGRRCQ-AEVDCGPPEEVKHATLRFNGTRLGAVALYACDRG 727
Query: 729 W-MGPDCSVEVCSV--------------DCGTHGVCIGGACR---------CEEGWTGAA 764
+ + + VC +C + GG+C+ C G+ GA
Sbjct: 728 YSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAH 787
Query: 765 C----DQRVCHPRCIEHGTCKDGK----CECREGWNGEHCT--IDGCPDL-CNGNGRCTL 813
C D+ HP C G+C++ C C G+ G HC +D C C GRC
Sbjct: 788 CELERDECRAHP-CRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES 846
Query: 814 GQNSWQCVCQTGWRGPGCNVAME 836
G ++ CVC + G C +
Sbjct: 847 GGGAYLCVCPESFFGYHCETVSD 869
Score = 98.6 bits (244), Expect = 8e-20
Identities = 90/340 (26%), Positives = 117/340 (34%), Gaps = 86/340 (25%)
Query: 575 DCPRNCHG------------NGECVSGV----------CHCFPGFLGADCAKAACPVLCS 612
+CPR HG +G C +G C C F G C + P C+
Sbjct: 566 ECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHC-EIGKPDSCA 624
Query: 613 GNGQYSKGTC---------QCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGN----CVCS 659
++ GTC C G+ G C++ + C C G+C D + C C
Sbjct: 625 SGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ 684
Query: 660 AGYKGEHCE-EVDCLDPTCSSHGV---------------CVNGECLCSPG---------- 693
AGY G C+ EVDC P H C G L +P
Sbjct: 685 AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGV 744
Query: 694 WGGLNCELARVQCPDQCSGHGTYLPDTG---LCSCDPNWMGPDCSVEVCSVDCGTHGVCI 750
W L +C Q HG D LC C + G C +E +C H
Sbjct: 745 WSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE--RDECRAHPCRN 802
Query: 751 GGACR---------CEEGWTGAACDQRV--CHPRCIEHG-TCKDGK----CECREGWNGE 794
GG+CR C G+ G C+ V C +HG C+ G C C E + G
Sbjct: 803 GGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGY 862
Query: 795 HCTIDGCPDL---CNGNGRCTLGQNSWQCVCQTGWRGPGC 831
HC P C G G C S C C+ G+ G C
Sbjct: 863 HCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 83.2 bits (204), Expect = 3e-15
Identities = 89/336 (26%), Positives = 122/336 (36%), Gaps = 63/336 (18%)
Query: 582 GNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPM-NQC 640
G+ CV H L + C C S + TC+C G+ G C+ + C
Sbjct: 525 GSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLC 584
Query: 641 IDPSCGGHGSCIDG----NCVCSAGYKGEHCE---EVDCLDPTCSSHGVCVNG----ECL 689
C G+C + +C C + G HCE C C + G C + +C
Sbjct: 585 SSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCD 644
Query: 690 CSPGWGGLNCELARVQC-PDQCSGHGTYLP-DTGL-CSCDPNWMGPDCSVEVCSVDCGT- 745
C PG+ G +CE+A C C GT DT C C +MG C EV DCG
Sbjct: 645 CPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEV---DCGPP 701
Query: 746 ----------HGVCIGGAC--RCEEGWTGAACDQ-RVCHPRCIEHGTCKDGKCECREGWN 792
+G +G C+ G++ +A + RVC P HG + +C E
Sbjct: 702 EEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP----HGVWSEPP-QCLE--- 753
Query: 793 GEHCTIDGCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGD--- 848
ID C C G C + C+C TG+ G C + + A N G
Sbjct: 754 -----IDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRN 808
Query: 849 --GLVDCLDP------------DCCLQSACQNSLLC 870
G C P D C S CQ+ C
Sbjct: 809 LPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC 844
Score = 77.0 bits (188), Expect = 2e-13
Identities = 64/248 (25%), Positives = 90/248 (36%), Gaps = 51/248 (20%)
Query: 580 CHGNGEC----VSGVCHCFPGFLGADC---------------------------AKAACP 608
C G C CHC G++G C A AC
Sbjct: 666 CVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACD 725
Query: 609 VLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKG 664
S + CQ + W + +++C C GSC D C+CS GY+G
Sbjct: 726 RGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG 785
Query: 665 EHCE--EVDCLDPTCSSHGVCVNGE----CLCSPGWGGLNCELARVQCPDQCSGHGTYLP 718
HCE +C C + G C N C C G+ G++CE C HG
Sbjct: 786 AHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCE 845
Query: 719 DTG---LCSCDPNWMGPDCSV--EVC-SVDCGTHGVCIGG----ACRCEEGWTGAACDQR 768
G LC C ++ G C + C S CG G C+ +C C+ G+TG C +
Sbjct: 846 SGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
Query: 769 VCHPRCIE 776
+ P ++
Sbjct: 906 LFPPTALK 913
Score = 35.8 bits (81), Expect = 0.60
Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 4/45 (8%)
Query: 671 DCLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCS 711
+C + C + G CV G C C PG+ G CELA ++ C+
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCT 1354
Score = 32.3 bits (72), Expect = 6.7
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
Query: 634 DVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE 668
+VP N C + C G+C+ G +C C G+KG CE
Sbjct: 1306 NVPGN-CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 32.3 bits (72), Expect = 6.7
Identities = 20/64 (31%), Positives = 26/64 (40%), Gaps = 7/64 (10%)
Query: 575 DCPRN-CHGNGECVSGV----CHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWK 629
+C N C G CV G C C PGF G C A V +S+ + + W+
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSE--TKAFPVWE 1367
Query: 630 GAEC 633
G C
Sbjct: 1368 GGVC 1371
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 124 bits (311), Expect = 1e-27
Identities = 95/329 (28%), Positives = 128/329 (38%), Gaps = 67/329 (20%)
Query: 570 LDSVQDCPRNCHGNGECVSGV----CHCFPGFLGADCAK-----AACPVLCSGNGQYSKG 620
LD + R CH C + CHC G+ G C A+ P L G+ G
Sbjct: 107 LDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVG 166
Query: 621 T--CQCYSGWKGAECDVPMNQCIDPSCGGHGSCID----GNCVCSA-GYKGEHCEE--VD 671
+ C C G+ G C + +++C C G+C D C C+ GY+G HCE ++
Sbjct: 167 SFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLE 226
Query: 672 CLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHG------------- 714
C C + C+ G CLC PG+ G CE+ +C HG
Sbjct: 227 CASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYG 286
Query: 715 ----------TYLPDTG-LCSCDPNWMGPDCSVEV---CSVDCGTHGVCI----GGACRC 756
++ G LC C P + G DC VEV S C G C G C C
Sbjct: 287 GVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHC 346
Query: 757 EEGWTGAACDQRV---CHPRCIEHGTCKDGK----CECREGWNGEHCTID--GCPD-LCN 806
+G+ G C++ V C+ GTC D C C E W G C++ GC C
Sbjct: 347 PDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCP 406
Query: 807 GNGRCT----LGQNSWQCVCQTGWRGPGC 831
C G +S+ C C G GP C
Sbjct: 407 LAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 108 bits (269), Expect = 1e-22
Identities = 91/337 (27%), Positives = 132/337 (39%), Gaps = 61/337 (18%)
Query: 580 CHGNGECV------SGV-CHCFPGFLGA-------DCAKAACPVLCSGNGQYSKGTCQCY 625
CH CV +G C+C PGF G +CA C + + C C
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCP 135
Query: 626 SGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE-EVD-CLDPTCSS 679
G+ G C++ +++C C GSC+DG CVC+ GY G C+ ++D C C+
Sbjct: 136 LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH 195
Query: 680 HGVC---VNG-ECLCS-PGWGGLNCELARVQCPDQ-CSGHGTYLPDTGL--CSCDPNWMG 731
G C VNG C C+ G+ G +CE ++C C + + L G C C P + G
Sbjct: 196 GGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255
Query: 732 PDCSVEVCSVDCGTHGVCIGGAC--RCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECRE 789
C V+ +C + GG C R + G + P C C
Sbjct: 256 ELCEVD--EDECASSPCQHGGRCLQRSDPALYGGV---QAAFPGAFSFRHAAGFLCHCPP 310
Query: 790 GWNGEHC--TIDGCPDL-CNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNE 846
G+ G C +D C C G C N +QC C G+ GP C
Sbjct: 311 GFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-------------- 356
Query: 847 GDGLVDCLDPDCCLQSACQNSL---LCR-----GSRD 875
+ + +CL C C +++ +CR G RD
Sbjct: 357 -EDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRD 392
Score = 87.8 bits (216), Expect = 1e-16
Identities = 74/269 (27%), Positives = 94/269 (34%), Gaps = 52/269 (19%)
Query: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCV-------NGEC 688
P + C C C S GY E C C +CV C
Sbjct: 38 PPSACASDPCAPGTEC---QATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 689 LCSPGWGGLNCELARVQCPDQCSGHGTY---LPDTGLCSCDPNWMGPDCSVEV---CSVD 742
C PG+ G CEL +C + HG L D C C + G C +EV S
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAP 154
Query: 743 CGTHGVCIGGA----CRCEEGWTGAAC--DQRVCHPR-CIEHGTCKD----GKCECR-EG 790
C G C+ G C C G+ G C D C + C GTC D +C+C G
Sbjct: 155 CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTG 214
Query: 791 WNGEHC---TIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG 847
+ G HC ++ C N C G S++C+C G+ G C V
Sbjct: 215 YEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV-------------- 260
Query: 848 DGLVDCLDPDCCLQSACQNSLLCRGSRDP 876
D D C S CQ+ C DP
Sbjct: 261 -------DEDECASSPCQHGGRCLQRSDP 282
Score = 67.4 bits (163), Expect = 2e-10
Identities = 48/160 (30%), Positives = 57/160 (35%), Gaps = 22/160 (13%)
Query: 697 LNCELARVQCPDQCSGHGTY--LPDTGLCSCDPNWMGPDCSVEV--CSVDCGTHGVCIGG 752
L C A V P C G L D C+C P W GP C V C G C
Sbjct: 1052 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTH 1111
Query: 753 A-----CRCEEGWTGAACDQRVCHPRCIEHGTCKDGK----------CECREGWNGEHCT 797
CRC G+ G C V C + TC DG C C EG G+ C
Sbjct: 1112 PDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQ 1171
Query: 798 IDGCP---DLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVA 834
+ P + C G C +C+C + G C VA
Sbjct: 1172 VPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVA 1211
Score = 55.5 bits (132), Expect = 7e-07
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 22/160 (13%)
Query: 598 LGADCAKAACPVLCSGNGQ----YSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSC-- 651
LG A P C +G + C C GW+G C+ ++ C C G C
Sbjct: 1052 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARGRCHT 1110
Query: 652 -IDG--NCVCSAGYKGEHCE----EVDC-LDPTCSSHGVCVNG----ECLCSPGWGGLNC 699
DG C C G+ G C +C L+ TC C G C C G G C
Sbjct: 1111 HPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC 1170
Query: 700 ELARVQC-PDQCSGHGTYLPDTGL--CSCDPNWMGPDCSV 736
++ + C + C GT G+ C C+ + G C V
Sbjct: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 52.0 bits (123), Expect = 8e-06
Identities = 41/159 (25%), Positives = 62/159 (38%), Gaps = 40/159 (25%)
Query: 577 PRNCHGNGECV----SGVCHCFPGFLG------------ADCAKAACPVLCSGNGQYSKG 620
P C +G C + C C PG+ G A CA+ C G +
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE---- 1117
Query: 621 TCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----------NCVCSAGYKGEHCE-- 668
C+C G+ G C +P+ C + +C+DG NC C G G+ C+
Sbjct: 1118 -CRCPPGFGGPRCRLPVPS---KECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP 1173
Query: 669 EVDCLDPTCSSHGVCVNG----ECLCSPGWGGLNCELAR 703
+ C C + G C EC+C+ + G CE+A+
Sbjct: 1174 TLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAK 1212
Score = 49.3 bits (116), Expect = 5e-05
Identities = 48/164 (29%), Positives = 58/164 (35%), Gaps = 22/164 (13%)
Query: 688 CLCSPGWGGLNCELARVQCPDQCSG---HGTYLPDTG--LCSCDPNWMGPDCSVEVCSVD 742
CL GGL LAR + P G H P T + C P C+ C D
Sbjct: 1013 CLGRVALGGLPLPLARPR-PGAAPGAREHFASWPGTPAPILGCRG---APVCAPSPCLHD 1068
Query: 743 CGTHGVCIGGACRCEEGWTGAACDQRV--CHPRCIEHGTC---KDGKCECR--EGWNGEH 795
+ AC C GW G C+ V CH G C DG+ ECR G+ G
Sbjct: 1069 GACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPR 1128
Query: 796 CTIDGCPDLCNGN------GRCTLGQNSWQCVCQTGWRGPGCNV 833
C + C+ N C G + C C G G C V
Sbjct: 1129 CRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV 1172
Score = 36.2 bits (82), Expect = 0.46
Identities = 27/109 (24%), Positives = 37/109 (33%), Gaps = 27/109 (24%)
Query: 791 WNGEHCTIDGC-------PDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME----TSC 839
W G I GC P C +G C +++ C C GW GP C ++ C
Sbjct: 1044 WPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC 1103
Query: 840 ADNK-DNEGDGLVDCLDP---------------DCCLQSACQNSLLCRG 872
A + DG +C P +C L C + C G
Sbjct: 1104 ARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEG 1152
Score = 32.7 bits (73), Expect = 5.1
Identities = 16/47 (34%), Positives = 21/47 (44%), Gaps = 3/47 (6%)
Query: 788 REGWNGEHCTI--DGC-PDLCNGNGRCTLGQNSWQCVCQTGWRGPGC 831
R+ WN + D C PD C G C + N + C C + GP C
Sbjct: 796 RQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 123 bits (308), Expect = 3e-27
Identities = 98/345 (28%), Positives = 144/345 (41%), Gaps = 71/345 (20%)
Query: 571 DSVQD-CPRN-CHGNGECV------SGVCHCFPGFLG-------ADCAKAACP--VLCSG 613
D+++D C N C G+ CV S +C C PG+ G C K +C +C
Sbjct: 68 DNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQ 127
Query: 614 NGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCE- 668
+ Y C C +G+ G C++ ++C C C DG +C C GY+G HC+
Sbjct: 128 DPIYP--VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL 185
Query: 669 EVD-CLDPTCSSHGVCVNG----ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPD---T 720
EVD C C + C+N C+C + G+NCEL +C Q +G D
Sbjct: 186 EVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGA 245
Query: 721 GLCSCDPNWMGPDCSV---EVCSVDCGTHGVCIGG----ACRCE-EGWTGAACD--QRVC 770
C C P ++G C + E S C G+C+ G +C C G+TG C+ +C
Sbjct: 246 YFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
Query: 771 HPR-CIEHGTCKDG----KCECREGWNGEHCTID--GC-PDLCNGNGRCT-------LGQ 815
+ C + TC+D C C G+ G C ID C + C NG C G+
Sbjct: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR 365
Query: 816 -------------NSWQCVCQTGWRGPGCNVAMETSCADNKDNEG 847
+ + C+CQ G+ G C + C+ N G
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDV-NECSSNPCQNG 409
Score = 111 bits (277), Expect = 1e-23
Identities = 90/344 (26%), Positives = 139/344 (40%), Gaps = 78/344 (22%)
Query: 580 CHGNGECVSGV----CHCFPGFLGA-------DCAKAACPVLCSGNGQYSKGTCQCYSGW 628
C C G+ C C PG+ G +CA C + + + TC C +
Sbjct: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216
Query: 629 KGAECDVPMNQCIDPSCGGHGSCIDGN----CVCSAGYKGEHCE--EVDCLDPTCSSHGV 682
G C++ +++C C +C D C C+ G+ G+HCE +C C G+
Sbjct: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL 276
Query: 683 CVNGE----CLCS-PGWGGLNCELARVQCPDQ-CSGHGTYLP--DTGLCSCDPNWMGPDC 734
CV+GE C C+ G+ G +CE C + C + T D C C P + G C
Sbjct: 277 CVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC 336
Query: 735 SVEV--CSVD-CGTHGVCI------------------------GGACRCEEGWTGAACDQ 767
+++ C+ + C ++G C+ G C C+ G+TG C++
Sbjct: 337 EIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEE 396
Query: 768 RV--CHPR-CIEHGTCKD----GKCEC------REGWNGEHCT--IDGCP-DLCNGNGRC 811
V C C GTC++ C C R + G C+ + GC C NG C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTC 456
Query: 812 TL----GQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLV 851
GQ+ + C+C +G+ G C +A S EGDG +
Sbjct: 457 IPHFQDGQHGFSCLCPSGYTGSLCEIATTLSF------EGDGFL 494
Score = 100 bits (248), Expect = 3e-20
Identities = 77/290 (26%), Positives = 117/290 (40%), Gaps = 52/290 (17%)
Query: 632 ECDVPMNQCIDPSCGGHGSCIDGN------CVCSAGYKGEHCEEV--DCLDPTCSSHGVC 683
+CD + C C G +C++ C C GY G CE C +C G+C
Sbjct: 66 DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGIC 125
Query: 684 ----VNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGL----CSCDPNWMGPDCS 735
+ C+C G+ G CE+ +C +G D G+ C C P + G C
Sbjct: 126 HQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQD-GIDGYSCFCVPGYQGRHCD 184
Query: 736 VEV--CSVD-CGTHGVCIGG----ACRCEEGWTGAACDQRV--CHPR-CIEHGTCKDGK- 784
+EV C+ D C C+ C C ++G C+ + C + C+ TC+D
Sbjct: 185 LEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALG 244
Query: 785 ---CECREGWNGEHCTI--DGCPDL-CNGNGRCTLGQNSWQCVCQ-TGWRGPGCNVAM-- 835
C+C G+ G+HC + D C C G C G+N + C C +G+ G C M
Sbjct: 245 AYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPL 304
Query: 836 --------ETSCADNKDN------EGDGLVDC-LDPDCCLQSACQNSLLC 870
+C D+ DN G C +D + C + CQ++ C
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGEC 354
Score = 81.3 bits (199), Expect = 1e-14
Identities = 63/220 (28%), Positives = 90/220 (40%), Gaps = 49/220 (22%)
Query: 608 PVLCSGNGQ--YSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG----NCVCSAG 661
P L GN + YS C C GW G C++ +++C C HG+C D +C C G
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAYHCTCEPG 1205
Query: 662 YKGEHCE-EVD-CLDPTCSSHGVCV---NG-ECLCSPGWGGLNCELARVQCPDQCSGHGT 715
Y G +CE ++D C C++ C+ NG CLC + G C +R
Sbjct: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSR------------ 1253
Query: 716 YLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGG----ACRCEEGWTGAACDQRV-- 769
LP T C E ++ C G C C C G+TG C++ +
Sbjct: 1254 -LPST------------VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE 1300
Query: 770 -CHPRCIEHGTCKD----GKCECREGWNGEHCTIDGCPDL 804
C+ G C+D +C C + GE C +D DL
Sbjct: 1301 CASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
Score = 79.7 bits (195), Expect = 4e-14
Identities = 60/198 (30%), Positives = 79/198 (39%), Gaps = 36/198 (18%)
Query: 672 CLDPTCSSHGVCVNG----------ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTG 721
CL + C++G C C GW G +CEL +C HG
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVA 1196
Query: 722 L--CSCDPNWMGPDCSVEV--C-SVDCGTHGVCI----GGACRCEEGWTGAACDQR---- 768
C+C+P + G +C V++ C S C CI G +C C +TG C Q
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 769 -VC-----HPRCIEHGTCKDG----KCECREGWNGEHCT--IDGCP-DLCNGNGRCTLGQ 815
VC + C G C + KC CR G+ GE C ID C D C G C
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 816 NSWQCVCQTGWRGPGCNV 833
N +QC+C + G C V
Sbjct: 1317 NKFQCLCDVAFAGERCEV 1334
Score = 53.1 bits (126), Expect = 4e-06
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 28/158 (17%)
Query: 572 SVQDCPRNCHGNGECVSGV----CHCFPGFLGADCAKAA--CPVLCSGNG----QYSKG- 620
++ +C N +G C V C C PG+ G +C C NG ++ G
Sbjct: 1177 NIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGY 1236
Query: 621 TCQCYSGWKGAEC-------DVPMNQCIDPSCGGHGSCIDG----NCVCSAGYKGEHCEE 669
+C C+ + G C V N+ + +C G+C + C+C G+ GE CE+
Sbjct: 1237 SCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEK 1296
Query: 670 --VDCLDPTCSSHGVCVN----GECLCSPGWGGLNCEL 701
+C C + G+C + +CLC + G CE+
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
Score = 51.2 bits (121), Expect = 1e-05
Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 25/133 (18%)
Query: 568 VVLDSVQDCPRNCHGNGECVSGV----CHCFPGFLGADCAKAACPVLCSGNGQ-----YS 618
V +D+ Q C C+S C CF F G C ++ P GN + Y+
Sbjct: 1213 VDIDNCQS--HQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYN 1270
Query: 619 KGT---------CQCYSGWKGAECDVPMNQCIDPSCGGHGSCID----GNCVCSAGYKGE 665
G C C G+ G C+ +++C C G C D C+C + GE
Sbjct: 1271 GGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGE 1330
Query: 666 HCEEVDCLDPTCS 678
C EVD D S
Sbjct: 1331 RC-EVDLADDLIS 1342
Score = 42.4 bits (98), Expect = 0.006
Identities = 35/131 (26%), Positives = 45/131 (34%), Gaps = 30/131 (22%)
Query: 774 CIEHGTCKD----GKCECREGWNGEHCTIDGCPDLC-----NGNGRC--TLGQNSWQCVC 822
C + TCKD C C + N D D C G+ C T G+ S+ C C
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 823 QTGWRGPGCNVAMETSCADNKDNEGD------------------GLVDCLDPDCCLQSAC 864
G+ G C + SC N G G +D D C S C
Sbjct: 99 PPGYSGTICETTIG-SCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPC 157
Query: 865 QNSLLCRGSRD 875
QN +C+ D
Sbjct: 158 QNGAVCQDGID 168
Score = 33.1 bits (74), Expect = 3.9
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 23/96 (23%)
Query: 798 IDGCPDL--CNGN-----GRCTLGQNSWQCVCQTGWRGPGC---------NVAMETSCAD 841
+ GC L CN N G C +S+ C C GW G C N + +C+D
Sbjct: 1134 VTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSD 1193
Query: 842 N------KDNEGDGLVDC-LDPDCCLQSACQNSLLC 870
G V+C +D D C C N C
Sbjct: 1194 RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATC 1229
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 119 bits (299), Expect = 3e-26
Identities = 79/252 (31%), Positives = 105/252 (41%), Gaps = 50/252 (19%)
Query: 577 PRNCHGNGECVS-GVCHCFPGFLGADCA------------KAACPVLCSGNGQYSKGTCQ 623
P C + CV G+C C PGF GA C+ + +CP G + + G CQ
Sbjct: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ 119
Query: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSC--IDGNCVCSAGYKGEHCEEVDCLDPTCSSHG 681
C + GA C+ P +CG HG C G C C G+ C C T ++
Sbjct: 120 CQADRWGARCEFPC------ACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAARC 172
Query: 682 VCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYL-PDTGLCSCDPNWMGPDCSVEVCS 740
G C+C PGW G C +C+ HG+ D+G C+C P W GP+C +
Sbjct: 173 EQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQ--- 222
Query: 741 VDCGTHGVC--IGGACRCEEGWTGAACD---------QRVCHP--RCIEHGTCK--DGKC 785
+C G C G C C G+ GA C+ + H RC + C G C
Sbjct: 223 CEC-VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC 281
Query: 786 E-CREGWNGEHC 796
E C GWNG C
Sbjct: 282 ESCEPGWNGTQC 293
Score = 108 bits (269), Expect = 1e-22
Identities = 81/250 (32%), Positives = 99/250 (39%), Gaps = 43/250 (17%)
Query: 623 QCYSGW--KGAECDVPMNQCIDPSCGGHGSCID-GNCVCSAGYKGEHCEE--------VD 671
QC +GW K EC +P+ + D +C C+ G C C G+ G HC D
Sbjct: 40 QCCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
Query: 672 CLDPT-CSSHGVC--VNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPN 728
C + C HG C G C C G CE P C HG P TG+C C+P
Sbjct: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEF-----PCACGPHGRCDPATGVCHCEPG 153
Query: 729 WMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGT-CK--DGKC 785
W C GAC C+ GW G R C RC HG+ C+ G+C
Sbjct: 154 WWSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRC 208
Query: 786 ECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC---------NVAME 836
CR GW G C C + GRC+ S +C C G+RG C V
Sbjct: 209 ACRPGWWGPECQ-QQCECV---RGRCSAA--SGECTCPPGFRGARCELPCPAGSHGVQCA 262
Query: 837 TSCADNKDNE 846
SC K NE
Sbjct: 263 HSCGRCKHNE 272
Score = 99.4 bits (246), Expect = 4e-20
Identities = 66/225 (29%), Positives = 90/225 (40%), Gaps = 44/225 (19%)
Query: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
C HG + +GVCHC PG+ + C + + + + G C C GW G C
Sbjct: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
Query: 636 PMNQCIDPSCGGHGSCID---GNCVCSAGYKGEHC-EEVDCLDPTCSSHGVCVNGECLCS 691
C HGS + G C C G+ G C ++ +C+ CS+ +GEC C
Sbjct: 193 --------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSA----ASGECTCP 240
Query: 692 PGWGGLNCELA------RVQCP---DQCSGHGTYLPDTGLC-SCDPNWMGPDCSVEVCSV 741
PG+ G CEL VQC +C + PDTG C SC+P W G C
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP---- 296
Query: 742 DCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCE 786
C G G +C+Q+ H R E G C+
Sbjct: 297 --------------CLPGTFGESCEQQCPHCRHGEACEPDTGHCQ 327
Score = 55.8 bits (133), Expect = 6e-07
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 30/150 (20%)
Query: 725 CDPNWMGPD--CSVEVCSVD--CGTHGVCIG-GACRCEEGWTGAACDQRV---------- 769
C W D C++ +C C VC+ G CRC+ G+ GA C R
Sbjct: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR 100
Query: 770 ----CHPRCIEHGTCKD--GKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQ 823
CHP HG C+ G C+C+ G C P C +GRC C C+
Sbjct: 101 ESCPCHP----HGQCEPATGACQCQADRWGARCEF---PCACGPHGRCDPATGV--CHCE 151
Query: 824 TGWRGPGCNVAMETSCADNKDNEGDGLVDC 853
GW C + + A + + G C
Sbjct: 152 PGWWSSTCRRPCQCNTAAARCEQATGACVC 181
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 119 bits (299), Expect = 3e-26
Identities = 101/326 (30%), Positives = 125/326 (38%), Gaps = 91/326 (27%)
Query: 589 GVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTC---------------QCYSGWKGAEC 633
G C C GF G C +A C + G G + TC +C +G++G +C
Sbjct: 669 GSCSCKAGFRGERC-QAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDC 727
Query: 634 --DVPM-----NQCIDPSCGG---HGSCIDGNCVCSAGYKGEHCEEVDCLD--------- 674
+ P+ N SCGG HG + G C C G GE CE DC +
Sbjct: 728 GQECPVGTFGVNCSSSCSCGGAPCHG--VTGQCRCPPGRTGEDCE-ADCPEGRWGLGCQE 784
Query: 675 --PTCSSHGVC--VNGECLCSPGWGGLNCE----------LARVQCPDQCSGHGTYLPDT 720
P C C G CLC PG+ G C+ + +C C+ G P T
Sbjct: 785 ICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRC--SCANDGHCHPAT 842
Query: 721 GLCSCDPNW-------------MGPDCSVEVCSVDCGTHGVC--IGGACRCEEGWTGAAC 765
G CSC P W GPDCS C+ G HG C I G C CE G+ G C
Sbjct: 843 GHCSCAPGWTGFSCQRACDTGHWGPDCS-HPCNCSAG-HGSCDAISGLCLCEAGYVGPRC 900
Query: 766 DQRV--------CHPRC-IEHGTCKD---GKCECREGWNG---EHCTIDG-----CPDLC 805
+Q+ C RC +HG D G C C GW G EH G C C
Sbjct: 901 EQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC 960
Query: 806 NGNGRCTLGQNSWQCVCQTGWRGPGC 831
N + C+C G RGP C
Sbjct: 961 NCTAGAACDAVNGSCLCPAGRRGPRC 986
Score = 116 bits (291), Expect = 3e-25
Identities = 104/361 (28%), Positives = 125/361 (34%), Gaps = 102/361 (28%)
Query: 580 CHGNGEC--VSGVCHCFPGFLGADCAKAACPV-----------LCSGNGQYS--KGTCQC 624
C C V G CHC PG++G C +A CP LC G G C C
Sbjct: 1005 CFNGASCDPVHGQCHCAPGWMGPSCLQA-CPAGLYGDNCRHSCLCQNGGTCDPVSGHCAC 1063
Query: 625 YSGWKGAECDVP-MNQCIDPSCGGHGSCIDGN--------CVCSAGYKGEHCEEVDCL-- 673
GW G C+ + + + C G C++G C+C AG+ G+ C+ CL
Sbjct: 1064 PEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQS-PCLRG 1122
Query: 674 --DPTCSSHGVC--------VNGECLCSPGWGGLNCELARVQCPD-----------QCSG 712
C+ C V G C C PG+ G CE A CP QC G
Sbjct: 1123 WFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQA---CPPGSFGEDCAQMCQCPG 1179
Query: 713 HGTYL-PDTGLCSCDPNWMGPDCSVEV--------CSVDCG--THGVCIG--GACRCEEG 759
P TG CSC + GP C C CG G C GACRC G
Sbjct: 1180 ENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTG 1239
Query: 760 WTGAACD----QRVCHPRCIEHGTCKDGK--------CECREGWNGEHCTIDGCPD---- 803
+ G C+ Q P C C G C C G G C GCP
Sbjct: 1240 FLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCE-RGCPQNRFG 1298
Query: 804 -------LCNGNGRCTLGQNSWQCVCQTGWRGPGCNVA-----------METSCADNKDN 845
C G C S C C GW G C +A +E SC +N
Sbjct: 1299 VGCEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC 1356
Query: 846 E 846
E
Sbjct: 1357 E 1357
Score = 115 bits (289), Expect = 5e-25
Identities = 100/337 (29%), Positives = 129/337 (38%), Gaps = 81/337 (24%)
Query: 574 QDCPRNCHGNGE---C--VSGVCHCFPGFLGADCAKAA--------CPVLCS----GNGQ 616
+DC + C GE C +G C C G+ G C + C LC G+
Sbjct: 1169 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCD 1228
Query: 617 YSKGTCQCYSGWKGAECDVPMNQC-IDPSCG-----GHGSCID---GNCVCSAGYKGEHC 667
+ G C+C +G+ G +C++ Q P+C G G+ D G C+C G G C
Sbjct: 1229 AATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC 1288
Query: 668 EE--------VDCLDPTCSSH--GVC--VNGECLCSPGWGGLNCELA------RVQCPDQ 709
E V C + TCS G+C NG C C GW G +CELA C +
Sbjct: 1289 ERGCPQNRFGVGC-EHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLE 1347
Query: 710 CSGH--GTYLPDTGLCSCDPNWMGPDCSVEVCSV---DCGTHGVC----------IGGAC 754
CS H T P TG C C P + G C C G G+C I G C
Sbjct: 1348 CSCHNNSTCEPATGTCRCGPGFYGQACE-HPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
Query: 755 RCEEGWTGAACDQ--------RVCHPRCIEHGTCK----DGKCECREGWNGEHCTID--- 799
C G+ G C++ CH RC G G C C G +G C +D
Sbjct: 1407 LCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRR 1466
Query: 800 -----GCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC 831
C C+ G S QC C G+ GP C
Sbjct: 1467 GQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1503
Score = 112 bits (281), Expect = 4e-24
Identities = 109/387 (28%), Positives = 131/387 (33%), Gaps = 108/387 (27%)
Query: 579 NCHGNGEC--VSGVCHCFPGFLGADCAKAACPVLCSGNGQYSK---------------GT 621
NC G C + G C C PG G C CP G G + G+
Sbjct: 612 NCANRGRCHRLYGACLCDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS 670
Query: 622 CQCYSGWKGAECDVPMNQ-CIDPSCGGHGSC--------IDGNCV--CSAGYKGEHCEE- 669
C C +G++G C P C +C + G C C AG++GE C +
Sbjct: 671 CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQE 730
Query: 670 --VDCLDPTCSSHGVC-------VNGECLCSPGWGGLNCELARVQCPD------------ 708
V CSS C V G+C C PG G +CE CP+
Sbjct: 731 CPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCE---ADCPEGRWGLGCQEICP 787
Query: 709 QCSGHGTYLPDTGLCSCDPN-------------WMGPDCSVEVCSVDCGTHGVC--IGGA 753
C P+TG C C P W GP C CS C G C G
Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS--CANDGHCHPATGH 844
Query: 754 CRCEEGWTGAACDQRVCH-----PRCIE-------HGTCK--DGKCECREGWNGEHCTID 799
C C GWTG +C QR C P C HG+C G C C G+ G C
Sbjct: 845 CSCAPGWTGFSC-QRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQ 903
Query: 800 --------GCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLV 851
GC C S C C GWRG C E +C G +
Sbjct: 904 CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFC----EHACP-----AGFFGL 954
Query: 852 DCLDP-DCCLQSAC---QNSLLCRGSR 874
DC +C +AC S LC R
Sbjct: 955 DCRSACNCTAGAACDAVNGSCLCPAGR 981
Score = 112 bits (281), Expect = 4e-24
Identities = 93/303 (30%), Positives = 114/303 (37%), Gaps = 64/303 (21%)
Query: 579 NCHGNGEC--VSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVP 636
NC C V+G C C G G CA+ CP G+ C C++G A CD
Sbjct: 961 NCTAGAACDAVNGSCLCPAGRRGPRCAET-CPAHTYGHN--CSQACACFNG---ASCDPV 1014
Query: 637 MNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVC--VNGECLCSPGW 694
QC SC+ C AG G++C CL C + G C V+G C C GW
Sbjct: 1015 HGQCHCAPGWMGPSCLQA---CPAGLYGDNCRH-SCL---CQNGGTCDPVSGHCACPEGW 1067
Query: 695 GGLNCEL------ARVQCPDQ--CSGHGTYLPDTGLCSCDPNWMGPDCSV--------EV 738
GL CE R C C G P TG C C W G C E
Sbjct: 1068 AGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEA 1127
Query: 739 CS--VDCGTHGVC--IGGACRCEEGWTGAACDQRVCHP-----RCIEHGTC--------- 780
C+ C C + GACRC G+TG+ C+Q C P C + C
Sbjct: 1128 CAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQ-ACPPGSFGEDCAQMCQCPGENPACHP 1186
Query: 781 KDGKCECREGWNGEHCTI--------DGCPDLCN--GNGRCTLGQNSWQCVCQTGWRGPG 830
G C C G++G C GC LC G C + C C TG+ G
Sbjct: 1187 ATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTD 1244
Query: 831 CNV 833
CN+
Sbjct: 1245 CNL 1247
Score = 105 bits (261), Expect = 8e-22
Identities = 101/376 (26%), Positives = 130/376 (34%), Gaps = 103/376 (27%)
Query: 579 NCHGNGEC--VSGVCHCFPGFLGADCAKAACP-----------VLCSGNGQYSK--GTCQ 623
+C G C V+G C C PG G +C + CP C+ G+ + G C
Sbjct: 569 SCQNGGTCDSVTGACRCPPGVSGTNC-EDGCPKGYYGKHCRKKCNCANRGRCHRLYGACL 627
Query: 624 CYSGWKGAECDVPMNQ-CIDPSCGGHGSCI----------DGNCVCSAGYKGEHCE---E 669
C G G C + P C C+ DG+C C AG++GE C+ E
Sbjct: 628 CDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECE 687
Query: 670 VDCLDPTCSSHGVC--------VNGEC--LCSPGWGGLNC------ELARVQCPDQCSGH 713
+ P C C V+GEC C G+ G +C V C CS
Sbjct: 688 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 747
Query: 714 GTYLPD-TGLCSCDPNWMGPDCSV------------EVC-----SVDCGTH-GVC----- 749
G TG C C P G DC E+C + C G C
Sbjct: 748 GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPG 807
Query: 750 -IGGACR--CEEGWTGAACDQRVCHPRCIEHGTC--KDGKCECREGWNGEHC-----TID 799
+G C+ C GW G +C R C G C G C C GW G C T
Sbjct: 808 FVGSRCQDVCPAGWYGPSCQTRC---SCANDGHCHPATGHCSCAPGWTGFSCQRACDTGH 864
Query: 800 GCPDLCNGNGRCTLGQNSWQ-----CVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCL 854
PD C+ C+ G S C+C+ G+ GP C E C
Sbjct: 865 WGPD-CSHPCNCSAGHGSCDAISGLCLCEAGYVGPRC----EQQCPQGH----------F 909
Query: 855 DPDCCLQSACQNSLLC 870
P C + CQ+ C
Sbjct: 910 GPGCEQRCQCQHGAAC 925
Score = 87.0 bits (214), Expect = 2e-16
Identities = 88/330 (26%), Positives = 107/330 (32%), Gaps = 85/330 (25%)
Query: 593 CFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECD-------VPMNQCIDPSC 645
C G DC+ G C C GW G C+ N SC
Sbjct: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570
Query: 646 GGHGSC--IDGNCVCSAGYKGEHCEE--------VDCLDP-TCSSHGVC--VNGECLCSP 692
G+C + G C C G G +CE+ C C++ G C + G CLC P
Sbjct: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDP 630
Query: 693 GWGGLNCELARVQCPDQCSGHG------TYLPDT-------GLCSCDPNWMGPDCSVE-- 737
G G C L CP G G P T G CSC + G C E
Sbjct: 631 GLYGRFCHLT---CPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECE 687
Query: 738 ----------VCSVDCGTHGVCIGGAC--RCEEGWTGAACDQRV--------CHPRCIEH 777
C+ G + G C RC G+ G C Q C C
Sbjct: 688 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 747
Query: 778 GT-CK--DGKCECREGWNGEHCTID--------GCPDLC------------NGNGRCTLG 814
G C G+C C G GE C D GC ++C G C G
Sbjct: 748 GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPG 807
Query: 815 QNSWQC--VCQTGWRGPGCNVAMETSCADN 842
+C VC GW GP C SCA++
Sbjct: 808 FVGSRCQDVCPAGWYGPSCQT--RCSCAND 835
Score = 53.9 bits (128), Expect = 2e-06
Identities = 77/323 (23%), Positives = 110/323 (34%), Gaps = 87/323 (26%)
Query: 580 CHGNGECVSGV---CHCFPGFLGADCA---------KAACPVLCSGN-GQYSKGTCQCYS 626
C G CV G CHC PGF G C C C G Y C+C
Sbjct: 133 CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSY---LCECKP 189
Query: 627 GWK---GAECDVPMNQCIDPSCGGHGSCID-----GNCVCSAGYK----GEHCEEVDCLD 674
G++ + + +N C + G C+ C C G++ G HC
Sbjct: 190 GFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVR---RS 246
Query: 675 PTCSSHGVCVN--------GECLCSPGW----GGLNCE------LARVQCPDQC-SGHGT 715
P + +G C++ C C G+ G CE QC C + G+
Sbjct: 247 PCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGS 306
Query: 716 YLPDTGLCSCDPNWM----GPDC------SVEVCSVDCG--THG---VCIGGACRCEEGW 760
+ C C + G C V C + G +HG G C C G+
Sbjct: 307 F-----KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 361
Query: 761 TGAACDQRVC--------HPRCIEHGTCKDG--KCECREGW--NGEHCTIDGCPDLCNGN 808
DQR C P C + T G +C C G+ + + C + + +
Sbjct: 362 E-LDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSR 420
Query: 809 G----RCTLGQNSWQCVCQTGWR 827
G CT S+QC C+ G+R
Sbjct: 421 GGCEHHCTNLAGSFQCSCEAGYR 443
Score = 50.1 bits (118), Expect = 3e-05
Identities = 70/307 (22%), Positives = 109/307 (35%), Gaps = 67/307 (21%)
Query: 596 GFLGADCAKAACPVLCSGNGQYSKGT---CQCYSGWKGAECDVPMNQCIDPSCGGHGSCI 652
G L A+C+ + LC G+ G+ C C G++G C +++C + G C+
Sbjct: 122 GCLSAECSAS----LCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCV 177
Query: 653 DGN----CVCSAGYKGEHCEEVDCL--------DPTCSSHGV---CVNGECLCSPGW--- 694
+ C C G++ H + CL + C H V C C PG+
Sbjct: 178 NTPGSYLCECKPGFR-LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQ 236
Query: 695 -GGLNCELARVQCPDQ---CSGHGTYLPDTGLCSCDPNWM----GPDC-SVEVCSVDCG- 744
G +C + R C ++ C + C C + G C V+ C+
Sbjct: 237 EDGRHC-VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQ 295
Query: 745 -THGVCIGG----ACRCEEGWTGAACDQRVCHPRCIE--------HGTCKDG-------- 783
HG C+ C C G+ A D R C+ +E +G C G
Sbjct: 296 CAHG-CLNTQGSFKCVCHAGYELGA-DGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP 353
Query: 784 KCECREGWNGEH-----CTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWR--GPGCNVAME 836
C C G+ + +D C D CT ++C C G+R GC
Sbjct: 354 LCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDV 413
Query: 837 TSCADNK 843
CA ++
Sbjct: 414 DECASSR 420
Score = 44.3 bits (103), Expect = 0.002
Identities = 35/128 (27%), Positives = 44/128 (34%), Gaps = 34/128 (26%)
Query: 576 CPRNCHGNG-------------ECVSGVCHCFPGFLGADCAKAA--------CPVLCSGN 614
CP HG G + +SG C C GF G C + C C +
Sbjct: 1378 CPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCD 1437
Query: 615 GQYS----KGTCQCYSGWKGAECDVPMNQ-------CIDPSCGGHGSC--IDGNCVCSAG 661
G G C C G GA C++ + + CGG C + G C C G
Sbjct: 1438 GGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDG 1497
Query: 662 YKGEHCEE 669
Y G C E
Sbjct: 1498 YMGPTCRE 1505
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 112,317,712
Number of Sequences: 37866
Number of extensions: 5597390
Number of successful extensions: 24473
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 442
Number of HSP's that attempted gapping in prelim test: 15838
Number of HSP's gapped (non-prelim): 3469
length of query: 2765
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2645
effective length of database: 13,703,598
effective search space: 36246016710
effective search space used: 36246016710
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.