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Search of human proteins with 110815800
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110815800 WD repeat domain 32 [Homo sapiens]
(559 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110815800 WD repeat domain 32 [Homo sapiens] 1164 0.0
gi|13376840 WD repeat domain 61 [Homo sapiens] 66 7e-11
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 58 2e-08
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 57 4e-08
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 57 4e-08
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 57 4e-08
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 56 1e-07
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 55 1e-07
gi|16554629 WD repeat domain 5 [Homo sapiens] 55 2e-07
gi|16554627 WD repeat domain 5 [Homo sapiens] 55 2e-07
gi|18641360 collectin sub-family member 12 [Homo sapiens] 55 2e-07
gi|113865883 WD repeat domain 38 [Homo sapiens] 55 2e-07
gi|4507703 tumor suppressing subtransferable candidate 1 [Homo s... 55 2e-07
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 54 3e-07
gi|26665869 WD repeat domain 51B [Homo sapiens] 54 3e-07
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 54 4e-07
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 53 6e-07
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 53 6e-07
gi|23199987 WD repeat domain 5B [Homo sapiens] 53 6e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 53 8e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 53 8e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 52 1e-06
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] 52 1e-06
gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo ... 52 2e-06
gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo ... 52 2e-06
gi|148529011 coronin, actin binding protein, 2B [Homo sapiens] 52 2e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 51 2e-06
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 51 2e-06
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 51 2e-06
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 51 2e-06
>gi|110815800 WD repeat domain 32 [Homo sapiens]
Length = 559
Score = 1164 bits (3011), Expect = 0.0
Identities = 559/559 (100%), Positives = 559/559 (100%)
Query: 1 MFPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAP 60
MFPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAP
Sbjct: 1 MFPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAP 60
Query: 61 SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG 120
SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG
Sbjct: 61 SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG 120
Query: 121 ARLFGWLKERSLGRGLFVDPARDNFRTMTSLYGSIHPADSVYLSTRTHGAVFNLEYSPDG 180
ARLFGWLKERSLGRGLFVDPARDNFRTMTSLYGSIHPADSVYLSTRTHGAVFNLEYSPDG
Sbjct: 121 ARLFGWLKERSLGRGLFVDPARDNFRTMTSLYGSIHPADSVYLSTRTHGAVFNLEYSPDG 180
Query: 181 SVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLR 240
SVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLR
Sbjct: 181 SVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLR 240
Query: 241 KLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFFHTRF 300
KLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFFHTRF
Sbjct: 241 KLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFFHTRF 300
Query: 301 LMRMRLTPDCSKMLISTSSGYLLILHDLDLTKSLEVGSYPILRARRTTSSSDLTTSSSSS 360
LMRMRLTPDCSKMLISTSSGYLLILHDLDLTKSLEVGSYPILRARRTTSSSDLTTSSSSS
Sbjct: 301 LMRMRLTPDCSKMLISTSSGYLLILHDLDLTKSLEVGSYPILRARRTTSSSDLTTSSSSS 360
Query: 361 GPRVSGSPCHHSDSNSSEKHMSRASQREGVSPRNSLEVVTPEVLGESDHGNCITSLQLHP 420
GPRVSGSPCHHSDSNSSEKHMSRASQREGVSPRNSLEVVTPEVLGESDHGNCITSLQLHP
Sbjct: 361 GPRVSGSPCHHSDSNSSEKHMSRASQREGVSPRNSLEVVTPEVLGESDHGNCITSLQLHP 420
Query: 421 KGWATLLRCSSNSDDEECTCVYEFQEGAPVRPVSPRCSLRLTHYIEEANVGRGYIKELCF 480
KGWATLLRCSSNSDDEECTCVYEFQEGAPVRPVSPRCSLRLTHYIEEANVGRGYIKELCF
Sbjct: 421 KGWATLLRCSSNSDDEECTCVYEFQEGAPVRPVSPRCSLRLTHYIEEANVGRGYIKELCF 480
Query: 481 SPDGRMISSPHGYGIRLLGFDKQCSELVDCLPKEASPLRVIRSLYSHNDVVLTTKFSPTH 540
SPDGRMISSPHGYGIRLLGFDKQCSELVDCLPKEASPLRVIRSLYSHNDVVLTTKFSPTH
Sbjct: 481 SPDGRMISSPHGYGIRLLGFDKQCSELVDCLPKEASPLRVIRSLYSHNDVVLTTKFSPTH 540
Query: 541 CQIASGCLSGRVSLYQPKF 559
CQIASGCLSGRVSLYQPKF
Sbjct: 541 CQIASGCLSGRVSLYQPKF 559
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 66.2 bits (160), Expect = 7e-11
Identities = 44/145 (30%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Query: 171 VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFATCS 229
+ ++ YSPDG L + +FD + K + TL E H + ++ F D++L T S
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTL-EGHAMPIRSLTFSPDSQLLVTAS 209
Query: 230 DDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTEDG 289
DD I ++D++ N TL GH SWV N+ + + V+S D +V +WD T
Sbjct: 210 DDGYIKIYDVQHANL-AGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRT--- 265
Query: 290 CPHKKFFHTRFLMRMRLTPDCSKML 314
C H F H + ++ + SK++
Sbjct: 266 CVHTFFDHQDQVWGVKYNGNGSKIV 290
Score = 47.8 bits (112), Expect = 3e-05
Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 173 NLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFATCSDD 231
+L +SPD +L A + + ++D + TLS H V N+ F D+ F + S D
Sbjct: 195 SLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLS-GHASWVLNVAFCPDDTHFVSSSSD 253
Query: 232 TTIALWDLRKLNTKVC--TLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281
++ +WD+ T+ C T H V ++Y+ N +V+ G D + I+D
Sbjct: 254 KSVKVWDV---GTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 58.2 bits (139), Expect = 2e-08
Identities = 44/124 (35%), Positives = 56/124 (45%), Gaps = 14/124 (11%)
Query: 6 PHSPGGDGSAG-AGAEEPTPHEGQAAATGPPSPLH----PGADATHPPPPARSPRRPGAP 60
P +PG G AG GA P +GQ TGPP P+ PGA T P A+ P G+P
Sbjct: 380 PGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGP--TGSP 437
Query: 61 SLSPAPRSGELGLPGAPESSTASAP----GEPSPPSPPCRRPGPDCRAKSRGRHGLGAGL 116
S P G G PG+P ++ P G+P P P + G G HG+ +
Sbjct: 438 GTSGPP--GSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFK-GEAGPKGEPGPHGIQGPI 494
Query: 117 GGPG 120
G PG
Sbjct: 495 GPPG 498
Score = 46.2 bits (108), Expect = 8e-05
Identities = 45/142 (31%), Positives = 50/142 (35%), Gaps = 30/142 (21%)
Query: 9 PGGDGSAGAGAEEPTPHEGQAAATGPPS-PLHPGADATHPPPPARSPR------------ 55
PG G G E P GQ A GPP P HPG D P A+
Sbjct: 152 PGPRGPQGIDGEPGVP--GQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVG 209
Query: 56 -RPGAPSLSPAPRSGELGLPGAPESSTASAP-GEPSPPSP-----------PCRRPGPDC 102
PG S+ P G GL G + + P GEP P P P +PG D
Sbjct: 210 LMPG--SVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDG 267
Query: 103 RAKSRGRHGLGAGLGGPGARLF 124
G G G PGAR F
Sbjct: 268 EPGRNGNPGEVGFAGSPGARGF 289
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/122 (31%), Positives = 46/122 (37%), Gaps = 11/122 (9%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRR--PGAP 60
P GP PGG G G E+ GQ GPP P P + R PG P
Sbjct: 958 PAGP--PGGPGDKGDPGED-----GQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLP 1010
Query: 61 SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG 120
PA G++G GA P P + P PGP+ A + G G +G G
Sbjct: 1011 G--PAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG 1068
Query: 121 AR 122
R
Sbjct: 1069 DR 1070
Score = 42.4 bits (98), Expect = 0.001
Identities = 46/141 (32%), Positives = 52/141 (36%), Gaps = 26/141 (18%)
Query: 6 PHSPGGDGSAGAG-----AEEPTPH--------EGQAAATGPPSPL-HPG-ADATHPPPP 50
P PG G AG+ A P PH +G GPP PG A PP P
Sbjct: 863 PGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGP 922
Query: 51 ARSPRRPGAPSLSPAPRSGELGLPGAPES-------STASAPGEPSPPSPPCR--RPGPD 101
A +P P P P + G GL G P S A PG P P +PGPD
Sbjct: 923 AGAP-GPAGPLGEPG-KEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPD 980
Query: 102 CRAKSRGRHGLGAGLGGPGAR 122
G G +G PG R
Sbjct: 981 GPPGPAGTTGQRGIVGMPGQR 1001
Score = 40.8 bits (94), Expect = 0.003
Identities = 36/103 (34%), Positives = 40/103 (38%), Gaps = 14/103 (13%)
Query: 5 GPHSPGGD----GSAG-AGAEEPTPHEGQAAATGPPSPLHPGADATHPPP-PARSPRRPG 58
GP P GD G G G + G GPP P A P P R P P
Sbjct: 1122 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPV 1181
Query: 59 APSL---SPAPRSGELGLPGAP----ESSTASAPGEPSPPSPP 94
PS +P P G +G PG E+ PGEP PP PP
Sbjct: 1182 GPSGKEGNPGPL-GPIGPPGVRGSVGEAGPEGPPGEPGPPGPP 1223
Score = 40.4 bits (93), Expect = 0.004
Identities = 42/145 (28%), Positives = 47/145 (32%), Gaps = 25/145 (17%)
Query: 9 PGGDGSAGA-GAEEPTPHEGQAAATGPPSPLHPGADATHPPP--PARSPRRPGAPSL--- 62
PG G AG G PT G GP P P P PA + PG
Sbjct: 1007 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGE 1066
Query: 63 -------SPAPRSGELGLPGAP-------ESSTASAPGEPSPPSPPCRR-----PGPDCR 103
PA G G PG P ++ PG P PP R PGP
Sbjct: 1067 RGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGP 1126
Query: 104 AKSRGRHGLGAGLGGPGARLFGWLK 128
+G HG G G R F L+
Sbjct: 1127 RGDKGDHGDRGDRGQKGHRGFTGLQ 1151
Score = 38.9 bits (89), Expect = 0.013
Identities = 39/112 (34%), Positives = 46/112 (41%), Gaps = 11/112 (9%)
Query: 9 PGGDGSAGA-GAEEPTPHEGQAAATGPPSPLH-PGADATHPPPPARSPR-RPGAPSLSPA 65
PG G G GA T + G G PL PG D PP + R +PG+ L P
Sbjct: 560 PGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGL-PG 618
Query: 66 PRSGELGLPGAP-ESSTASAPGEPSPPSP-----PCRRPGPDCRAKSRGRHG 111
P+ G G PG P E+ A PG+ P P GP A RG G
Sbjct: 619 PK-GSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG 669
Score = 38.5 bits (88), Expect = 0.016
Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 4/54 (7%)
Query: 48 PPPARSPRRPGAPSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPD 101
PP ++ PR P P PR G G+ G P PG P PP P PGPD
Sbjct: 136 PPGSQGPRGERGPKGRPGPR-GPQGIDGEP--GVPGQPGAPGPPGHP-SHPGPD 185
Score = 37.7 bits (86), Expect = 0.028
Identities = 31/93 (33%), Positives = 35/93 (37%), Gaps = 24/93 (25%)
Query: 5 GPHSPGGD-GSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPP--PARSPRRPGAPS 61
GP P G+ GSAG G GPP P+ P +P P P P G+
Sbjct: 1155 GPPGPNGEQGSAGI--------PGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSV- 1205
Query: 62 LSPAPRSGELGLPGAPESSTASAPGEPSPPSPP 94
GE G G P PG P PP PP
Sbjct: 1206 -------GEAGPEGPP-----GEPGPPGPPGPP 1226
Score = 37.4 bits (85), Expect = 0.037
Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 19/130 (14%)
Query: 6 PHSPGGDGSAG-AGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSP 64
P S G G+ G GA G + GP P PG P + PR
Sbjct: 1079 PGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGP--PGRAGKRGLPGPQGPRGDKGDHGDR 1136
Query: 65 APR--------SGELGLPGAP----ESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGL 112
R +G GLPG P E +A PG P P PGP + G G
Sbjct: 1137 GDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGP----PGPVGPSGKEGNPGP 1192
Query: 113 GAGLGGPGAR 122
+G PG R
Sbjct: 1193 LGPIGPPGVR 1202
Score = 36.6 bits (83), Expect = 0.062
Identities = 37/126 (29%), Positives = 46/126 (36%), Gaps = 12/126 (9%)
Query: 6 PHSPGGDGSAGA-GAEEPTPHEGQAAATGPPSPL-HPGADATHPPPPARS-PRRPGAPSL 62
P PG G G G+ P G+ G P +PG P AR P PG P L
Sbjct: 239 PGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL 298
Query: 63 S--------PAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGA 114
P+ GE+G PG+ + + P P P PG R +G G
Sbjct: 299 KGHRGHKGLEGPK-GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRG 357
Query: 115 GLGGPG 120
G PG
Sbjct: 358 AHGMPG 363
Score = 35.8 bits (81), Expect = 0.11
Identities = 41/147 (27%), Positives = 47/147 (31%), Gaps = 38/147 (25%)
Query: 6 PHSPGGDGSAGAGAEEPTPHE-GQAAATGPPSPL-----HPGADATHPPPPARSPRRPGA 59
P PG G G E P E G+ TG P H P P+ +P G
Sbjct: 698 PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGP 757
Query: 60 PSLSPAPRSGELGLPGAP----------------ESSTASAPGEPSPPSPPCR------- 96
P L P GE G+ G P + A G P P PP
Sbjct: 758 PGLQGMP--GERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEK 815
Query: 97 -RPGPDCRAKSRGRHGLGAGLGGPGAR 122
PGP RG G G PG+R
Sbjct: 816 GEPGP------RGLVGPPGSRGNPGSR 836
Score = 35.4 bits (80), Expect = 0.14
Identities = 39/127 (30%), Positives = 49/127 (38%), Gaps = 14/127 (11%)
Query: 6 PHSPGGDGSAGA-GAEEPTPHEGQAAATGPPSPLHPGADATHPPPP--ARSPRRPGAPSL 62
P S G +G GA G P +GQ G P DA P P A SP P P+
Sbjct: 833 PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG-PHGPNG 891
Query: 63 SPAPRSGELGLPGAPESS----TASAPGEPSP-----PSPPCRRPGPDCRAKSRGRHGLG 113
P + G G G P ++ +A G P P P+ P PG + RG G
Sbjct: 892 VPGLKGGR-GTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSH 950
Query: 114 AGLGGPG 120
+G G
Sbjct: 951 GRVGDRG 957
Score = 34.7 bits (78), Expect = 0.24
Identities = 43/143 (30%), Positives = 50/143 (34%), Gaps = 22/143 (15%)
Query: 2 FPFGPHSPGGDGSAG-AGAEEPTPH------EGQAAATGPPSPLHPGADATHP------- 47
FP P PG G G G E P +G+A TGP + P P
Sbjct: 289 FPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG 348
Query: 48 PPPARSPR----RPGAPS-LSPAPRSGELGLPGAPESSTASAP-GEPSPPSPPCRR--PG 99
P A R PG P + P G G PG P + P G P P +R G
Sbjct: 349 PQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408
Query: 100 PDCRAKSRGRHGLGAGLGGPGAR 122
P S G G G PGA+
Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAK 431
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 6/153 (3%)
Query: 157 PADSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNN 216
P Y T AV + +SP G +L V ++ P + K T+ AH V +
Sbjct: 12 PQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP-NVKGESTVFRAHTATVRS 70
Query: 217 IRFL-DNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDG 275
+ F D + F T SDD T+ +W + + +L H +WV+ ++ + RL+V++ D
Sbjct: 71 VHFCSDGQSFVTASDDKTVKVWATHRQKF-LFSLSQHINWVRCAKFSPDGRLIVSASDDK 129
Query: 276 NVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTP 308
V +WD + C H H F+ + P
Sbjct: 130 TVKLWDK---SSRECVHSYCEHGGFVTYVDFHP 159
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 166 RTHGA-VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNR 223
R H A V ++ + DG A + V ++ K + +LS+ H + V +F D R
Sbjct: 62 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQ-HINWVRCAKFSPDGR 120
Query: 224 LFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTN 283
L + SDD T+ LWD + V + H +V +++ + + +G D V +WD
Sbjct: 121 LIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR 179
Query: 284 RY 285
+
Sbjct: 180 TH 181
Score = 42.7 bits (99), Expect = 9e-04
Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 3/116 (2%)
Query: 169 GAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDN-RLFAT 227
G V +++ P G+ + A V ++D + + + + H VN + F + T
Sbjct: 150 GFVTYVDFHPSGTCIAAAGMDNTVKVWD-VRTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 208
Query: 228 CSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTN 283
S D+T+ + DL + + TLHGH + + + G D V++W +N
Sbjct: 209 ASSDSTLKILDLME-GRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 263
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 6/153 (3%)
Query: 157 PADSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNN 216
P Y T AV + +SP G +L V ++ P + K T+ AH V +
Sbjct: 50 PQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP-NVKGESTVFRAHTATVRS 108
Query: 217 IRFL-DNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDG 275
+ F D + F T SDD T+ +W + + +L H +WV+ ++ + RL+V++ D
Sbjct: 109 VHFCSDGQSFVTASDDKTVKVWATHRQKF-LFSLSQHINWVRCAKFSPDGRLIVSASDDK 167
Query: 276 NVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTP 308
V +WD + C H H F+ + P
Sbjct: 168 TVKLWDK---SSRECVHSYCEHGGFVTYVDFHP 197
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 166 RTHGA-VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNR 223
R H A V ++ + DG A + V ++ K + +LS+ H + V +F D R
Sbjct: 100 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQ-HINWVRCAKFSPDGR 158
Query: 224 LFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTN 283
L + SDD T+ LWD + V + H +V +++ + + +G D V +WD
Sbjct: 159 LIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR 217
Query: 284 RY 285
+
Sbjct: 218 TH 219
Score = 42.7 bits (99), Expect = 9e-04
Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 3/116 (2%)
Query: 169 GAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDN-RLFAT 227
G V +++ P G+ + A V ++D + + + + H VN + F + T
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWD-VRTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 246
Query: 228 CSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTN 283
S D+T+ + DL + + TLHGH + + + G D V++W +N
Sbjct: 247 ASSDSTLKILDLME-GRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 301
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 6/153 (3%)
Query: 157 PADSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNN 216
P Y T AV + +SP G +L V ++ P + K T+ AH V +
Sbjct: 50 PQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP-NVKGESTVFRAHTATVRS 108
Query: 217 IRFL-DNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDG 275
+ F D + F T SDD T+ +W + + +L H +WV+ ++ + RL+V++ D
Sbjct: 109 VHFCSDGQSFVTASDDKTVKVWATHRQKF-LFSLSQHINWVRCAKFSPDGRLIVSASDDK 167
Query: 276 NVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTP 308
V +WD + C H H F+ + P
Sbjct: 168 TVKLWDK---SSRECVHSYCEHGGFVTYVDFHP 197
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 166 RTHGA-VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNR 223
R H A V ++ + DG A + V ++ K + +LS+ H + V +F D R
Sbjct: 100 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQ-HINWVRCAKFSPDGR 158
Query: 224 LFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTN 283
L + SDD T+ LWD + V + H +V +++ + + +G D V +WD
Sbjct: 159 LIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR 217
Query: 284 RY 285
+
Sbjct: 218 TH 219
Score = 42.7 bits (99), Expect = 9e-04
Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 3/116 (2%)
Query: 169 GAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDN-RLFAT 227
G V +++ P G+ + A V ++D + + + + H VN + F + T
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWD-VRTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 246
Query: 228 CSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTN 283
S D+T+ + DL + + TLHGH + + + G D V++W +N
Sbjct: 247 ASSDSTLKILDLME-GRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 301
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 55.8 bits (133), Expect = 1e-07
Identities = 44/134 (32%), Positives = 51/134 (38%), Gaps = 18/134 (13%)
Query: 6 PHSPGGDGSAGAGAEEPTPH----EGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPS 61
P +PGG G AGA E P G GPP P G A PP P + PG
Sbjct: 668 PGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGP-EGGKGAAGPPGPPGAAGTPGLQG 726
Query: 62 L--------SPAPRS--GELGLPGA---PESSTASAPGEPSPPSPPCRRPGPDCRAKSRG 108
+ SP P+ GE G PGA P P P P P +PG + G
Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786
Query: 109 RHGLGAGLGGPGAR 122
G+ G PG R
Sbjct: 787 LPGIAGPRGSPGER 800
Score = 54.7 bits (130), Expect = 2e-07
Identities = 57/181 (31%), Positives = 65/181 (35%), Gaps = 40/181 (22%)
Query: 13 GSAGAGAEEPTPHEGQAAATGPPSPLHPGADA--THPPPP---------ARSPRRPGAPS 61
G G G + P G+ GPP P PG D T PP P P G P
Sbjct: 598 GPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPG 657
Query: 62 LSPAPRSGELGLPGAP-ESSTASAPGEPSPP------------SPP--------CRRPGP 100
P P+ G+ G PGAP A APGE PP PP PGP
Sbjct: 658 -EPGPK-GDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715
Query: 101 DCRAKSRGRHGL---GAGLGGPGARLFGWLKERSLGRGLFVDPARDNFRTMTSLYGSIHP 157
A + G G+ GLG PG + K G G P +D R T G P
Sbjct: 716 PGAAGTPGLQGMPGERGGLGSPGPK---GDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772
Query: 158 A 158
A
Sbjct: 773 A 773
Score = 53.9 bits (128), Expect = 4e-07
Identities = 46/117 (39%), Positives = 52/117 (44%), Gaps = 15/117 (12%)
Query: 8 SPGGDGSAG-AGAEEPTPHEGQAAATGPPSPL-HPGADATHPPPPARSPRRPGAPSLSPA 65
SPGG G+AG GA G GPP P PG D PP PA + PG+P +S
Sbjct: 865 SPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG--PPGPAGNTGAPGSPGVS-G 921
Query: 66 PRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPGAR 122
P+ G+ G PG S PG PP PGP A G GL G PG R
Sbjct: 922 PK-GDAGQPGEKGS-----PGAQGPPG----APGPLGIAGITGARGLAGPPGMPGPR 968
Score = 53.1 bits (126), Expect = 6e-07
Identities = 45/136 (33%), Positives = 50/136 (36%), Gaps = 23/136 (16%)
Query: 6 PHSPGGDGSAGAGAEEPTP-HEGQAAATGPPSPLHPGADATHPPPP-----ARSPRRPGA 59
P PG +G GA E P G A G P P + P P A P R G
Sbjct: 470 PGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGV 529
Query: 60 PSLSPAPRSGELGLPGAPESSTASAP-------GEPSPPSPPCRR--------PGPDCRA 104
P P R G G PG P S P G P PP P R PGP
Sbjct: 530 PG-GPGMR-GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND 587
Query: 105 KSRGRHGLGAGLGGPG 120
+ G++G G GGPG
Sbjct: 588 GAPGKNGERGGPGGPG 603
Score = 52.0 bits (123), Expect = 1e-06
Identities = 46/125 (36%), Positives = 52/125 (41%), Gaps = 27/125 (21%)
Query: 2 FPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHP-GADATHPPPPARSPRRPGAP 60
FP P +PG G AG +P G A GP P P G D T P P PG
Sbjct: 1111 FPGNPGAPGSPGPAGQQGAIGSP--GPAGPRGPVGPSGPPGKDGTSGHPGPIGP--PG-- 1164
Query: 61 SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLG----AGL 116
P GE G G+P PG+P PP PP PGP C G+G AG+
Sbjct: 1165 ---PRGNRGERGSEGSP-----GHPGQPGPPGPP-GAPGPCC-------GGVGAAAIAGI 1208
Query: 117 GGPGA 121
GG A
Sbjct: 1209 GGEKA 1213
Score = 50.4 bits (119), Expect = 4e-06
Identities = 46/124 (37%), Positives = 47/124 (37%), Gaps = 15/124 (12%)
Query: 3 PFGPHSPGGD-GSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPS 61
P GP P G G G G P G A G P T PP PA P GAP
Sbjct: 766 PIGPPGPAGQPGDKGEGGAPGLP--GIAGPRGSPGE----RGETGPPGPAGFP---GAPG 816
Query: 62 LSPAPRS-GELGLPGAPESSTASAPGEPSPP--SPPCRRPGPDCRAKSRGRHGLGAGLGG 118
+ P GE G PG E PG PP S P PGP RG G G
Sbjct: 817 QNGEPGGKGERGAPG--EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGF 874
Query: 119 PGAR 122
PGAR
Sbjct: 875 PGAR 878
Score = 48.5 bits (114), Expect = 2e-05
Identities = 42/125 (33%), Positives = 47/125 (37%), Gaps = 16/125 (12%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPH-EGQAAATGPPSPLH-PGADATHPPPPAR-SPRRPGA 59
P P G G G E P G + GPP P PG T P +P G
Sbjct: 962 PGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGL 1021
Query: 60 PSLSPAPRS----GELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAG 115
P +P GE G PGAP APG P PP P GP ++ RG G
Sbjct: 1022 PGRDGSPGGKGDRGENGSPGAP-----GAPGHPGPPGP----VGPAGKSGDRGESGPAGP 1072
Query: 116 LGGPG 120
G PG
Sbjct: 1073 AGAPG 1077
Score = 47.8 bits (112), Expect = 3e-05
Identities = 41/119 (34%), Positives = 51/119 (42%), Gaps = 13/119 (10%)
Query: 6 PHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHP--GADATHPPPP--ARSPR-RPGAP 60
P +PG +G G E P G+ GPP P G+ PP P + R PG P
Sbjct: 812 PGAPGQNGEPGGKGERGAP--GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869
Query: 61 SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGP 119
+ P G GLPG P S+ PG P P P + GP A + G G G+ GP
Sbjct: 870 GAAGFP--GARGLPGPPGSN--GNPGPPGPSGSP-GKDGPPGPAGNTGAPG-SPGVSGP 922
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/127 (29%), Positives = 42/127 (33%), Gaps = 10/127 (7%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARS--------P 54
P GP GD +G P G A + G P P P D + P
Sbjct: 1054 PVGPAGKSGDRGE-SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP 1112
Query: 55 RRPGAP-SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLG 113
PGAP S PA + G +G PG P P PGP RG G
Sbjct: 1113 GNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGER 1172
Query: 114 AGLGGPG 120
G PG
Sbjct: 1173 GSEGSPG 1179
Score = 43.9 bits (102), Expect = 4e-04
Identities = 45/140 (32%), Positives = 52/140 (37%), Gaps = 29/140 (20%)
Query: 5 GPHSPGG-DGSAG--AGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPAR--------S 53
GP P G +G+ G GA EP G+ A G P P +A P P S
Sbjct: 414 GPPGPAGANGAPGLRGGAGEP----GKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGS 469
Query: 54 PRRPGAPSLSPAPRSGELGLPG----------APESSTASAPGEPSPPSP--PCRRPGPD 101
P PGA L A +GE G PG E A G P P P PG D
Sbjct: 470 PGEPGANGLPGA--AGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527
Query: 102 CRAKSRGRHGLGAGLGGPGA 121
G G+ GGPG+
Sbjct: 528 GVPGGPGMRGMPGSPGGPGS 547
Score = 43.5 bits (101), Expect = 5e-04
Identities = 41/122 (33%), Positives = 48/122 (39%), Gaps = 21/122 (17%)
Query: 3 PFGPHSPGGDGSAGA-GAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPS 61
P P + G GS G+ G + P GQA +GPP P PGA PS
Sbjct: 182 PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP--PGAIG---------------PS 224
Query: 62 LSPAPRSGELGLPGAP-ESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG 120
PA + GE G PG P E PG P P PG GR+G G PG
Sbjct: 225 -GPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP-GFPGMKGHRGFDGRNGEKGETGAPG 282
Query: 121 AR 122
+
Sbjct: 283 LK 284
Score = 41.6 bits (96), Expect = 0.002
Identities = 43/131 (32%), Positives = 47/131 (35%), Gaps = 25/131 (19%)
Query: 8 SPGGDGSAGAGAEEPTPHE-GQAAATGPPSPLHP-------GADATHPPPPARSPRRPGA 59
+PG G +G + P E G A GPP P GA PP PR G+
Sbjct: 913 APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR--GS 970
Query: 60 PSLSPAPRSGELGLPGAPESSTASAPGEPSPPSP--------PCRRPGPDCRAKSRGRHG 111
P P GE G PGA S GE PP P PG D S G G
Sbjct: 971 PG--PQGVKGESGKPGANGLS-----GERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023
Query: 112 LGAGLGGPGAR 122
GG G R
Sbjct: 1024 RDGSPGGKGDR 1034
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/127 (33%), Positives = 50/127 (39%), Gaps = 19/127 (14%)
Query: 3 PFGPH-SPGGDGSAGA-GAEEPTPHEGQAAATGPPS-------PLHPGADATHPPPPARS 53
P GP +PG GS GA G + P +G+ G P +PGA + P PA
Sbjct: 1069 PAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS--PGPAGQ 1126
Query: 54 PRRPGAPSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLG 113
G+P PA G +G G P S G P P P PGP RG G
Sbjct: 1127 QGAIGSPG--PAGPRGPVGPSGPPGKDGTS--GHPGPIGP----PGPRGNRGERGSEGSP 1178
Query: 114 AGLGGPG 120
G PG
Sbjct: 1179 GHPGQPG 1185
Score = 41.2 bits (95), Expect = 0.003
Identities = 45/141 (31%), Positives = 53/141 (37%), Gaps = 32/141 (22%)
Query: 3 PFGPHS-PGGDGSAGA-GAEEPTPHEGQAAATG-------------PPSPLHPGADATHP 47
P GP+ PG G AG GA P G A G P SP PG+D
Sbjct: 493 PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPG 552
Query: 48 PPPARSPR-RPGAPSLS-PAPRSGELGLPG------AP----ESSTASAPGEPSPP---- 91
PP ++ RPG P S P + G +G PG AP E PG PP
Sbjct: 553 PPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNG 612
Query: 92 -SPPCRRPGPDCRAKSRGRHG 111
+ P PGP +G G
Sbjct: 613 ETGPQGPPGPTGPGGDKGDTG 633
Score = 40.4 bits (93), Expect = 0.004
Identities = 40/128 (31%), Positives = 47/128 (36%), Gaps = 31/128 (24%)
Query: 6 PHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGAD--ATHPPPPARSPRRPGAPSLS 63
P SPGG GS G P +G++ GPP P P P P + PG
Sbjct: 539 PGSPGGPGSDGKPG--PPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPG----- 591
Query: 64 PAPRSGELGLPGAP-ESSTASAPGEPSPPSPP-----------CRRPGPDCRAKSRGRHG 111
++GE G PG P GE P PP PGP +G G
Sbjct: 592 ---KNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP------QGLQG 642
Query: 112 LGAGLGGP 119
L G GGP
Sbjct: 643 L-PGTGGP 649
Score = 40.0 bits (92), Expect = 0.006
Identities = 39/117 (33%), Positives = 45/117 (38%), Gaps = 27/117 (23%)
Query: 6 PHSPGGDGSAG-AGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSP 64
P SPG G G AG+ GQ GP H GA PG P ++
Sbjct: 344 PGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQG--HAGAQGP-----------PGPPGING 390
Query: 65 APRS-GELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG 120
+P GE+G G P APG P PGP A + G GL G G PG
Sbjct: 391 SPGGKGEMGPAGIP-----GAPGLMGARGP----PGP---AGANGAPGLRGGAGEPG 435
Score = 37.0 bits (84), Expect = 0.048
Identities = 42/158 (26%), Positives = 48/158 (30%), Gaps = 38/158 (24%)
Query: 3 PFGPHSPGG----DGSAGAGAEEPTP-HEGQAAATGPPSPLHPGADATHPPPPARS---- 53
P GP P G G AG E P G+ GPP P P
Sbjct: 211 PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDG 270
Query: 54 -------------------PRRPGAPS-LSPAPRSGELGLPGAPESSTA-------SAPG 86
P GAP + P GE G PG P ++ A + G
Sbjct: 271 RNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDG 330
Query: 87 EPSPPSPP--CRRPGPDCRAKSRGRHGLGAGLGGPGAR 122
+P PP PP PG G G G PG R
Sbjct: 331 QPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQR 368
Score = 35.0 bits (79), Expect = 0.18
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 12/67 (17%)
Query: 27 GQAAATGPPSPLHPGA--DATHPPPPARSPRRPGAPSLSPAPRSGELGLPGAPESSTASA 84
G+ A P P P + P P P PG P R+G+ G+PG P S
Sbjct: 82 GECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPG-----RNGDPGIPGQPGS----- 131
Query: 85 PGEPSPP 91
PG P PP
Sbjct: 132 PGSPGPP 138
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 55.5 bits (132), Expect = 1e-07
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 13/180 (7%)
Query: 169 GAVFNLEYSP--DGSVLTVACEQTEVLLFDPIS--SKHIKTLS-EAHEDCVNNIRF--LD 221
G F L++SP G +LT C Q + L+ P S H+ H V ++++ +
Sbjct: 215 GEGFALDWSPRVTGRLLTGDC-QKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTE 273
Query: 222 NRLFATCSDDTTIALWDLRKLNTKVC---TLHGHTSWVKNIEYDTNTRLLVTSGFDGNVI 278
N +FA+CS D +I +WD+R +K C T H V I + L++ G DG +
Sbjct: 274 NTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALK 333
Query: 279 IWDTNRYTEDGCPHKKF-FHTRFLMRMRLTPDCSKMLISTSSGYLLILHDLDLTKSLEVG 337
IWD ++ + G P F H + + P S + ++ + + + DL + + E G
Sbjct: 334 IWDLRQF-KSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEAG 392
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 55.1 bits (131), Expect = 2e-07
Identities = 32/113 (28%), Positives = 63/113 (55%), Gaps = 3/113 (2%)
Query: 170 AVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFATC 228
AV ++++SP+G L + + ++ K KT+S H+ ++++ + D+ L +
Sbjct: 47 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTIS-GHKLGISDVAWSSDSNLLVSA 105
Query: 229 SDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281
SDD T+ +WD+ + TL GH+++V ++ + L+V+ FD +V IWD
Sbjct: 106 SDDKTLKIWDVSS-GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/113 (28%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
Query: 171 VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFATCS 229
+ ++ +S D ++L A + + ++D S K +KTL + H + V F + L + S
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGS 148
Query: 230 DDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDT 282
D ++ +WD+ K + TL H+ V + ++ + L+V+S +DG IWDT
Sbjct: 149 FDESVRIWDV-KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDT 200
Score = 35.0 bits (79), Expect = 0.18
Identities = 29/134 (21%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 203 IKTLSEAHEDCVNNIRFLDN-RLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEY 261
+K H V++++F N A+ S D I +W + T+ GH + ++ +
Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEK-TISGHKLGISDVAW 95
Query: 262 DTNTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGY 321
+++ LLV++ D + IWD + C H+ ++ P S +++S S
Sbjct: 96 SSDSNLLVSASDDKTLKIWDV---SSGKCLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDE 151
Query: 322 LLILHDLDLTKSLE 335
+ + D+ K L+
Sbjct: 152 SVRIWDVKTGKCLK 165
Score = 32.7 bits (73), Expect = 0.90
Identities = 25/111 (22%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 174 LEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDN-RLFATCSDDT 232
+ ++ DGS++ + ++D S + +KTL + V+ ++F N + + D
Sbjct: 177 VHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDN 236
Query: 233 TIALWDLRKLN-TKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVI-IWD 281
T+ LWD K K T H + + + + SG + N++ IW+
Sbjct: 237 TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 287
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 55.1 bits (131), Expect = 2e-07
Identities = 32/113 (28%), Positives = 63/113 (55%), Gaps = 3/113 (2%)
Query: 170 AVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFATC 228
AV ++++SP+G L + + ++ K KT+S H+ ++++ + D+ L +
Sbjct: 47 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTIS-GHKLGISDVAWSSDSNLLVSA 105
Query: 229 SDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281
SDD T+ +WD+ + TL GH+++V ++ + L+V+ FD +V IWD
Sbjct: 106 SDDKTLKIWDVSS-GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/113 (28%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
Query: 171 VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFATCS 229
+ ++ +S D ++L A + + ++D S K +KTL + H + V F + L + S
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGS 148
Query: 230 DDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDT 282
D ++ +WD+ K + TL H+ V + ++ + L+V+S +DG IWDT
Sbjct: 149 FDESVRIWDV-KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDT 200
Score = 35.0 bits (79), Expect = 0.18
Identities = 29/134 (21%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 203 IKTLSEAHEDCVNNIRFLDN-RLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEY 261
+K H V++++F N A+ S D I +W + T+ GH + ++ +
Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEK-TISGHKLGISDVAW 95
Query: 262 DTNTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGY 321
+++ LLV++ D + IWD + C H+ ++ P S +++S S
Sbjct: 96 SSDSNLLVSASDDKTLKIWDV---SSGKCLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDE 151
Query: 322 LLILHDLDLTKSLE 335
+ + D+ K L+
Sbjct: 152 SVRIWDVKTGKCLK 165
Score = 32.7 bits (73), Expect = 0.90
Identities = 25/111 (22%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Query: 174 LEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDN-RLFATCSDDT 232
+ ++ DGS++ + ++D S + +KTL + V+ ++F N + + D
Sbjct: 177 VHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDN 236
Query: 233 TIALWDLRKLN-TKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVI-IWD 281
T+ LWD K K T H + + + + SG + N++ IW+
Sbjct: 237 TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 287
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 54.7 bits (130), Expect = 2e-07
Identities = 40/122 (32%), Positives = 47/122 (38%), Gaps = 5/122 (4%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSL 62
P GP P GD + G PT ++GQ G P P P + P R G S
Sbjct: 444 PPGPRGPRGDRGS-QGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSK 502
Query: 63 SPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRR--PGPDCRAKSRGRHGLGAGLGGPG 120
G G PG P S G+P PP PP + PGP +G G G PG
Sbjct: 503 GSQGPKGSRGSPGKPGPQGPS--GDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPG 560
Query: 121 AR 122
R
Sbjct: 561 PR 562
Score = 47.4 bits (111), Expect = 4e-05
Identities = 34/105 (32%), Positives = 40/105 (38%), Gaps = 20/105 (19%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARS--PRRPGAP 60
P GP P G+ G G++ +G + G P P P D P PP + P G P
Sbjct: 486 PIGPAGPPGE-RGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPP 544
Query: 61 SLS-----------PAPRSGELGLPGAPESSTASAPGEPSPPSPP 94
P PR G GLPG P PG PP PP
Sbjct: 545 GFQGLQGTVGEPGVPGPR-GLPGLPGVP-----GMPGPKGPPGPP 583
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/114 (31%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Query: 169 GAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFAT 227
G V + +SPDG +L E V ++ S + + L H V RF D LFA+
Sbjct: 22 GEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLG-GHTGPVKFCRFSPDGHLFAS 80
Query: 228 CSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281
S D T+ LWD+ + + L GH V+ + + ++R L + G+D V++WD
Sbjct: 81 ASCDCTVRLWDVARAKC-LRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Score = 48.5 bits (114), Expect = 2e-05
Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 169 GAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFAT 227
G V +SPDG + A V L+D +K ++ L + H+ V + F D+R A+
Sbjct: 64 GPVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVL-KGHQRSVETVSFSPDSRQLAS 122
Query: 228 CSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYT 286
D + LWD++ + L GH +++ ++ L T +D V IWD T
Sbjct: 123 GGWDKRVMLWDVQS-GQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVT 180
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/158 (23%), Positives = 60/158 (37%), Gaps = 45/158 (28%)
Query: 170 AVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDN-RLFATC 228
+V + +SPD L V+L+D S + ++ L H D + + F AT
Sbjct: 107 SVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLV-GHRDSIQSSDFSPTVNCLATG 165
Query: 229 SDDTTIALWDLRKLNTKVC-----------------------------TLH--------- 250
S D+T+ +WDLR + V T+H
Sbjct: 166 SWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASGLLASGSWDKTIHIWKPTTSSL 225
Query: 251 -----GHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTN 283
GH +WVK+I + + L ++G+ V +WD N
Sbjct: 226 LIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCN 263
Score = 33.9 bits (76), Expect = 0.40
Identities = 37/146 (25%), Positives = 62/146 (42%), Gaps = 10/146 (6%)
Query: 210 HEDCVNNIRFL-DNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLL 268
H VN+ F D ++ T S+D + W+ R + L GHT VK + + L
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRS-GQLLWRLGGHTGPVKFCRFSPDGHLF 78
Query: 269 VTSGFDGNVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHDL 328
++ D V +WD R C H R + + +PD S+ L S ++L D+
Sbjct: 79 ASASCDCTVRLWDVARAK---CLRVLKGHQRSVETVSFSPD-SRQLASGGWDKRVMLWDV 134
Query: 329 DLTKSLEVGSYPILRARRTTSSSDLT 354
+ L + ++ R + SSD +
Sbjct: 135 QSGQMLRL----LVGHRDSIQSSDFS 156
Score = 32.3 bits (72), Expect = 1.2
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 14/81 (17%)
Query: 475 IKELCFSPDGRMISSPHGYGIRLLGFDKQCSELVDCLPKEASPLRVIRSLYSHNDVVLTT 534
++ + FSPD R ++S G+ R++ +D Q ++ +R L H D + ++
Sbjct: 108 VETVSFSPDSRQLASG-GWDKRVMLWDVQSGQM-------------LRLLVGHRDSIQSS 153
Query: 535 KFSPTHCQIASGCLSGRVSLY 555
FSPT +A+G V ++
Sbjct: 154 DFSPTVNCLATGSWDSTVHIW 174
Score = 31.2 bits (69), Expect = 2.6
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 18/85 (21%)
Query: 473 GYIKELCFSPDGRMISSPHGYGIRLLGFDKQCSELVDCLPK--EASPLRVIRSLYSHNDV 530
G +K FSPDG + +S DC + + + + +R L H
Sbjct: 64 GPVKFCRFSPDGHLFASAS----------------CDCTVRLWDVARAKCLRVLKGHQRS 107
Query: 531 VLTTKFSPTHCQIASGCLSGRVSLY 555
V T FSP Q+ASG RV L+
Sbjct: 108 VETVSFSPDSRQLASGGWDKRVMLW 132
>gi|4507703 tumor suppressing subtransferable candidate 1 [Homo
sapiens]
Length = 387
Score = 54.7 bits (130), Expect = 2e-07
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 4/108 (3%)
Query: 176 YSPDGSVLTVA-CEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLF--ATCSDDT 232
+SP + VA T + +D S I + AH V ++ F N+ + A+C DD
Sbjct: 192 WSPHHNCTQVATANDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDC 251
Query: 233 TIALWDLRKLNTKVCTLHGHTSWVKNIEYD-TNTRLLVTSGFDGNVII 279
+ WD R + V TL H+ WV N+ Y+ ++ +L++T D VI+
Sbjct: 252 KVKFWDTRNVTEPVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVIL 299
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 162 YLSTRTH-GAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNI--R 218
Y + + H GAV L Y+ DGS+L A V ++D + + +K L + H VN+
Sbjct: 102 YATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRL-KGHTSFVNSCYPA 160
Query: 219 FLDNRLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVI 278
+L T SDD T+ LWD+RK + T +T V + ++ + +++ G D ++
Sbjct: 161 RRGPQLVCTGSDDGTVKLWDIRK-KAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIK 218
Query: 279 IWD 281
+WD
Sbjct: 219 VWD 221
Score = 37.7 bits (86), Expect = 0.028
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 206 LSEAHEDCVNNIRFLDN-RLFATCSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTN 264
L HE V +F N A+ D I LW++ TL GH+ V + Y+T+
Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD 120
Query: 265 TRLLVTSGFDGNVIIWDT 282
+L ++ D V +WD+
Sbjct: 121 GSMLFSASTDKTVAVWDS 138
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 54.3 bits (129), Expect = 3e-07
Identities = 33/113 (29%), Positives = 59/113 (52%), Gaps = 3/113 (2%)
Query: 171 VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRF-LDNRLFATCS 229
V ++++SP G++L A V L+ P +AH V ++ F D + AT S
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEF-KAHTAPVRSVDFSADGQFLATAS 121
Query: 230 DDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDT 282
+D +I +W + + + +L+ HT WV+ ++ + RL+V+ D + IWDT
Sbjct: 122 EDKSIKVWSMYRQRF-LYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDT 173
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/160 (23%), Positives = 78/160 (48%), Gaps = 9/160 (5%)
Query: 170 AVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEA-HEDCVNNIRFLDN-RLFAT 227
A+ +L+ SP+G L A T ++L++ H + H+D V +++F + L A+
Sbjct: 20 AITSLDLSPNGKQLATASWDTFLMLWN--FKPHARAYRYVGHKDVVTSVQFSPHGNLLAS 77
Query: 228 CSDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTE 287
S D T+ LW K K HT+ V+++++ + + L T+ D ++ +W R
Sbjct: 78 ASRDRTVRLWIPDKRG-KFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR--- 133
Query: 288 DGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHD 327
+ + HT ++ + +PD ++++S S + + D
Sbjct: 134 QRFLYSLYRHTHWVRCAKFSPD-GRLIVSCSEDKTIKIWD 172
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 3/111 (2%)
Query: 174 LEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDN-RLFATCSDDT 232
++++P G+ + A V ++D +K ++ + H VN I F + T S D
Sbjct: 192 VDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHY-QVHSGGVNCISFHPSGNYLITASSDG 250
Query: 233 TIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTN 283
T+ + DL + + TL GHT V + + L + G D V++W TN
Sbjct: 251 TLKILDLLE-GRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTN 300
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 9/111 (8%)
Query: 175 EYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATC----SD 230
++SPDG ++ E + ++D + + + S D V F+D TC
Sbjct: 151 KFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFS----DSVGFANFVDFNPSGTCIASAGS 206
Query: 231 DTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281
D T+ +WD+R +N + H+ V I + + L+T+ DG + I D
Sbjct: 207 DQTVKVWDVR-VNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILD 256
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 53.9 bits (128), Expect = 4e-07
Identities = 42/115 (36%), Positives = 44/115 (38%), Gaps = 17/115 (14%)
Query: 2 FPFGPHSPGGDGSA-GAGAEEPTPHEGQAAATGPPSPLHPGA-----------DATHPPP 49
FP GP PGG AG P P G GPP P PG PPP
Sbjct: 217 FP-GPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPP 275
Query: 50 PARSPRRP-GAPSLSPAPRSGELGLP--GAPESSTASAPGEPSPPSP-PCRRPGP 100
P P +P G P L P P +P G P G P PP P P R PGP
Sbjct: 276 PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGP 330
Score = 40.8 bits (94), Expect = 0.003
Identities = 35/117 (29%), Positives = 39/117 (33%), Gaps = 34/117 (29%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSL 62
P GP PG P P G GPP P PPPP P RP P
Sbjct: 288 PLGPLPPG----------PPPPVPGYGPPPGPPPP-----QQGPPPPPGPFPPRPPGPLG 332
Query: 63 SPAPRSGELGLPGAPESSTASAP-------------GEPS------PPSPPCRRPGP 100
P + LPG P + AP G P+ PP+ P RP P
Sbjct: 333 PPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
Score = 33.1 bits (74), Expect = 0.69
Identities = 30/108 (27%), Positives = 35/108 (32%), Gaps = 30/108 (27%)
Query: 10 GGDGSAGAGAEEPTPHEGQAAATGP---------PSPLHPGADATHPPPPARSPRRPGAP 60
G G G + P G+ P P P PG PPPP + + P P
Sbjct: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG----PPPPFPAGQTPPRP 239
Query: 61 SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRG 108
L P PG P G P PP P P P +RG
Sbjct: 240 PLGP---------PGPP--------GPPGPPPPGQVLPPPLAGPPNRG 270
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 53.1 bits (126), Expect = 6e-07
Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
Query: 171 VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFL-DNRLFATCS 229
+ +L++ P G + + T + L+D I K H V +RF D + A+ +
Sbjct: 108 ICSLDFHPYGEFVASGSQDTNIKLWD-IRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAA 166
Query: 230 DDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTEDG 289
DD T+ LWDL + GHT V +E+ N LL + D + WD ++
Sbjct: 167 DDHTVKLWDLTA-GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVS 225
Query: 290 C 290
C
Sbjct: 226 C 226
Score = 46.6 bits (109), Expect = 6e-05
Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
Query: 197 PISSKHIKTLSE--AHEDCVNNIRF--LDNRLFATCSDDTTIALWDLRKLNTKVCTLHGH 252
P+ +K L E AH V+++ RL AT DD + LW + K N + +L GH
Sbjct: 4 PVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNC-IMSLTGH 62
Query: 253 TSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281
TS V+++ +T L+V G++ +WD
Sbjct: 63 TSPVESVRLNTPEELIVAGSQSGSIRVWD 91
Score = 43.5 bits (101), Expect = 5e-04
Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Query: 170 AVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNR-LFATC 228
AV L +SPDG L A + V L+D + K + H VN + F N L A+
Sbjct: 149 AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVVEFHPNEYLLASG 207
Query: 229 SDDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDG-NVIIWDTNR 284
S D TI WDL K C + G V+++ ++ + L + D V W+ R
Sbjct: 208 SSDRTIRFWDLEKFQVVSC-IEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPER 263
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 7/156 (4%)
Query: 180 GSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRF-LDNRLFATCSDDTTIALWD 238
G +L + V L+ I +L+ H V ++R L S +I +WD
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLT-GHTSPVESVRLNTPEELIVAGSQSGSIRVWD 91
Query: 239 LRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFFHT 298
L + TL GH + + ++++ + + D N+ +WD R GC + H+
Sbjct: 92 LEAAKI-LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR---KGCVFRYRGHS 147
Query: 299 RFLMRMRLTPDCSKMLISTSSGYLLILHDLDLTKSL 334
+ + +R +PD K L S + + + L DL K +
Sbjct: 148 QAVRCLRFSPD-GKWLASAADDHTVKLWDLTAGKMM 182
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 53.1 bits (126), Expect = 6e-07
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 13/130 (10%)
Query: 181 SVLTVACEQTEVLLFDPISSKHIKT--LSEAHEDCVNNIRF--LDNRLFATCSDDTTIAL 236
S+ + +++++D S+ K L +AH VN + F + AT S D T+AL
Sbjct: 240 SLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 299
Query: 237 WDLRKLNTKVCTLHGHTSWVKNIEYDT-NTRLLVTSGFDGNVIIWDTNRY--------TE 287
WDLR L K+ T H + + + N +L +SG D + +WD ++ E
Sbjct: 300 WDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAE 359
Query: 288 DGCPHKKFFH 297
DG P F H
Sbjct: 360 DGPPELLFIH 369
Score = 35.4 bits (80), Expect = 0.14
Identities = 41/199 (20%), Positives = 76/199 (38%), Gaps = 25/199 (12%)
Query: 152 YGSIHPADSVYLSTRTHGAVFNLEYSPDGS-VLTVACEQTEVLLFDPISSKHIKTLSEAH 210
+GS+ + G V Y P ++ ++VL+FD +KH +
Sbjct: 107 FGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFD--YTKH-PAKPDPS 163
Query: 211 EDCVNNIRFLDNRL--------------FATCSDDTTIALWDLR------KLNTKVCTLH 250
+C ++R ++ + SDD T+ LWD+ K+
Sbjct: 164 GECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFT 223
Query: 251 GHTSWVKNIEYDT-NTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFFHTRFLMRMRLTPD 309
GH++ V+++ + + L + D ++IWDT T H HT + + P
Sbjct: 224 GHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPY 283
Query: 310 CSKMLISTSSGYLLILHDL 328
+L + S+ + L DL
Sbjct: 284 SEFILATGSADKTVALWDL 302
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 53.1 bits (126), Expect = 6e-07
Identities = 30/112 (26%), Positives = 59/112 (52%), Gaps = 1/112 (0%)
Query: 170 AVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATCS 229
AV ++++SP+G L + ++++ K+ KTL + + + D+ + S
Sbjct: 43 AVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSAS 102
Query: 230 DDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281
DD T+ LWD+R + TL GH+++V ++ + L+++ FD V IW+
Sbjct: 103 DDKTLKLWDVRS-GKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWE 153
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 3/112 (2%)
Query: 171 VFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLD-NRLFATCS 229
+ ++ +S D S L A + + L+D S K +KTL + H + V F + L + S
Sbjct: 86 ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTL-KGHSNYVFCCNFNPPSNLIISGS 144
Query: 230 DDTTIALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWD 281
D T+ +W++ K + TL H+ V + ++ + L+V+ +DG IWD
Sbjct: 145 FDETVKIWEV-KTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD 195
Score = 35.4 bits (80), Expect = 0.14
Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
Query: 247 CTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRYTEDGCPHKKFF-HTRFLMRMR 305
CTL GHT V ++++ N L +S D +IIW DG K + H + +
Sbjct: 35 CTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWG----AYDGKYEKTLYGHNLEISDVA 90
Query: 306 LTPDCSKMLISTSSGYLLILHDLDLTKSLE 335
+ D S+ L+S S L L D+ K L+
Sbjct: 91 WSSDSSR-LVSASDDKTLKLWDVRSGKCLK 119
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 52.8 bits (125), Expect = 8e-07
Identities = 45/129 (34%), Positives = 54/129 (41%), Gaps = 19/129 (14%)
Query: 5 GPHSPGGD-GSAGAGAEEPTP-HEGQAAATGPPSPLHPGAD--ATHPPPPARSPRRPGAP 60
GP P GD G AG E H G G P P P D A+ P P+ PR P P
Sbjct: 1110 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS-GPRGPPGP 1168
Query: 61 SLSPAPRSGELGLPG----------APESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRH 110
+ P+ + G G+PG + E+ A PG P PP PP PGP +
Sbjct: 1169 -VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP-GPPGPGIDMSAFA-- 1224
Query: 111 GLGAGLGGP 119
GLG GP
Sbjct: 1225 GLGPREKGP 1233
Score = 50.8 bits (120), Expect = 3e-06
Identities = 42/127 (33%), Positives = 52/127 (40%), Gaps = 13/127 (10%)
Query: 6 PHSPGGDGSAG-AGAEEPTPHEGQAAATGPPSPLHP-GADATHPPPPARSPRRPGAPSLS 63
P +PG GS G AG G+A A GP P P GA P + PR +
Sbjct: 1067 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP---QGPRGDKGEAGE 1123
Query: 64 PAPR--------SGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAG 115
P R +G GLPG P S P+ PS P PGP + G +G+
Sbjct: 1124 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP 1183
Query: 116 LGGPGAR 122
+G PG R
Sbjct: 1184 IGPPGPR 1190
Score = 50.1 bits (118), Expect = 5e-06
Identities = 43/120 (35%), Positives = 48/120 (40%), Gaps = 29/120 (24%)
Query: 3 PFGPHS-PGGDGSAG-AGAEEPTPHEGQAAATGPPSPL----------HPGADATHPPPP 50
P GP PG G G AGA ++GQ GPP P+ PGA P
Sbjct: 322 PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG 381
Query: 51 ARSPR-------RPGAPSLSPAP-----RSGELGLPGAPESS----TASAPGEPSPPSPP 94
AR P PG P SP P G G+PGA S+ A APG P P PP
Sbjct: 382 ARGPEGAQGPRGEPGTPG-SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 440
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/114 (32%), Positives = 47/114 (41%), Gaps = 9/114 (7%)
Query: 9 PGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAP-R 67
PG G +G ++ P G + GPP P+ P PA P R G+P P R
Sbjct: 995 PGLPGPSGEPGKQGAP--GASGDRGPPGPVGPPGLTG----PAGEPGREGSPGADGPPGR 1048
Query: 68 SGELGLPG-APESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG 120
G G+ G E+ APG P PP P GP + RG G +G G
Sbjct: 1049 DGAAGVKGDRGETGAVGAPGAPGPPGSP-GPAGPTGKQGDRGEAGAQGPMGPSG 1101
Score = 46.6 bits (109), Expect = 6e-05
Identities = 44/152 (28%), Positives = 51/152 (33%), Gaps = 31/152 (20%)
Query: 3 PFGPHSPGGD-GSAGA-GAEEPTPHEGQAAATGPPSPLHPGADATHP------------- 47
P G P GD G G GA P +G+ G P P P P
Sbjct: 127 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 186
Query: 48 ---------------PPPARSPRRPGAPSLSPAPRSGELGLPGAPESSTASAPGEPSPPS 92
P PR P P+ +P P+ G G PG P S P P P
Sbjct: 187 FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQ-GFQGNPGEPGEPGVSGPMGPRGPP 245
Query: 93 PPCRRPGPDCRAKSRGRHGLGAGLGGPGARLF 124
P +PG D A G+ G G GAR F
Sbjct: 246 GPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/128 (31%), Positives = 46/128 (35%), Gaps = 11/128 (8%)
Query: 5 GPH-SPGGDGSAGA----GAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGA 59
GP +PG DG G G P G+ GPP P G+ P R P
Sbjct: 774 GPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA--GSAGARGAPGERGETGPPG 831
Query: 60 PSLSPAPRSGELGLPGAP-ESSTASAPGEPSPPSP--PCRRPGPDCRAKSRGRHGLGAGL 116
P+ P + G PGA E A G+ P P P PGP G G
Sbjct: 832 PAGFAGPPGAD-GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890
Query: 117 GGPGARLF 124
G PGA F
Sbjct: 891 GPPGATGF 898
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/129 (33%), Positives = 50/129 (38%), Gaps = 19/129 (14%)
Query: 9 PGGDGSAGAGAEEPTP-HEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAPR 67
PG G AG E+ P +G + A GPP P P + R G P L P P
Sbjct: 944 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGER-GFPGL-PGP- 1000
Query: 68 SGELGLPGAPESS-------TASAPGEPSPPSPPCRR--------PGPDCRAKSRGRHGL 112
SGE G GAP +S PG P P R PG D A +G G
Sbjct: 1001 SGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE 1060
Query: 113 GAGLGGPGA 121
+G PGA
Sbjct: 1061 TGAVGAPGA 1069
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/132 (27%), Positives = 44/132 (33%), Gaps = 38/132 (28%)
Query: 6 PHSPGGDGSAGAGAEEPTP----------HEGQAAATGPPSPLHPGADATHPPPPARS-- 53
P G +G G E+ P +G+ A GPP P P + P S
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664
Query: 54 ---PRRPGAPSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRH 110
P PG P P G+ G+PG A APG P RG
Sbjct: 665 QGLPGPPGPPGEGGKP--GDQGVPG-----EAGAPGLVGP----------------RGER 701
Query: 111 GLGAGLGGPGAR 122
G G PGA+
Sbjct: 702 GFPGERGSPGAQ 713
Score = 39.3 bits (90), Expect = 0.010
Identities = 43/136 (31%), Positives = 49/136 (36%), Gaps = 26/136 (19%)
Query: 9 PGGDGSAGAGAEE-PTPHEGQAAATGP------PSPLHP-------GADATHPPPPARSP 54
PG DG GA E+ +G A A GP P P P GA PP A
Sbjct: 839 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG- 897
Query: 55 RRPGAPS-LSPAPRSGELGLPGAPESSTASAP----GEPSPP----SPPCRRP-GPDCRA 104
PGA + P +G G PG P S P G+ PP P + P GP
Sbjct: 898 -FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 956
Query: 105 KSRGRHGLGAGLGGPG 120
G G G PG
Sbjct: 957 GEPGDDGPSGAEGPPG 972
Score = 38.5 bits (88), Expect = 0.016
Identities = 50/165 (30%), Positives = 57/165 (34%), Gaps = 47/165 (28%)
Query: 5 GPHSPGGD-GSAGA-GAEEPTPHEGQAAATGPPSPL----------------HPGADATH 46
G P G+ G AG GA P EG+ A G P + PG D
Sbjct: 465 GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA 524
Query: 47 PPPPARSPRRP----GAPSLSPAP-RSGELGLPGA-----------PESST--ASAPGE- 87
P A R P G + P R GE GLPGA P+ + APGE
Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 584
Query: 88 --PSPPSPPCRR--------PGPDCRAKSRGRHGLGAGLGGPGAR 122
P PP P R PGP G+ G G PG R
Sbjct: 585 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 629
Score = 37.7 bits (86), Expect = 0.028
Identities = 42/159 (26%), Positives = 47/159 (29%), Gaps = 43/159 (27%)
Query: 1 MFPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPAR-----SPR 55
M P GP P G AGA P +G G P P P PP +
Sbjct: 203 MGPMGPRGPPGP----AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258
Query: 56 RPG-APSLSPAPRSGELGLPGAP----------------------------ESSTASAPG 86
+PG A P G G PG P ES + G
Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 318
Query: 87 EPSPPSP-----PCRRPGPDCRAKSRGRHGLGAGLGGPG 120
P P P R GP A +RG G G PG
Sbjct: 319 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 357
Score = 37.0 bits (84), Expect = 0.048
Identities = 37/121 (30%), Positives = 44/121 (36%), Gaps = 11/121 (9%)
Query: 9 PGGDGSAG-AGAEEPTPHEGQAAATGPPSPLHP----GADATHPPPPARSPR----RPGA 59
PG DG+ G AGA G G P P+ P G P A R +PG
Sbjct: 293 PGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG- 351
Query: 60 PSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGP 119
P+ P P G G PG P + A P+ P GP + G G G P
Sbjct: 352 PAGPPGP-VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP 410
Query: 120 G 120
G
Sbjct: 411 G 411
Score = 35.0 bits (79), Expect = 0.18
Identities = 40/145 (27%), Positives = 48/145 (33%), Gaps = 25/145 (17%)
Query: 3 PFGPHSPGGDGSAG--AGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPR-RPGA 59
P P PG DG AG A E P Q A P +P PG P + GA
Sbjct: 245 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304
Query: 60 PSL-----------SPAP-----------RSGELGLPGAPESSTASAPGEPSPPSPPCRR 97
P + SP P R+G G GA + P P P P
Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 364
Query: 98 PGPDCRAKSRGRHGLGAGLGGPGAR 122
PG ++G G G GA+
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQ 389
Score = 35.0 bits (79), Expect = 0.18
Identities = 34/131 (25%), Positives = 42/131 (32%), Gaps = 19/131 (14%)
Query: 6 PHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPL----------HPGADATHPP------P 49
P PG G G ++ P G+A A G P PGA P P
Sbjct: 668 PGPPGPPGEGGKPGDQGVP--GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 725
Query: 50 PARSPRRPGAPSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGR 109
P+ P+ P G GL G P A+ P GP+ G
Sbjct: 726 GTDGPKGASGPA-GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784
Query: 110 HGLGAGLGGPG 120
GL +G PG
Sbjct: 785 RGLTGPIGPPG 795
Score = 33.9 bits (76), Expect = 0.40
Identities = 28/92 (30%), Positives = 31/92 (33%), Gaps = 20/92 (21%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSL 62
P G GD G + P +G A GP + GAP
Sbjct: 102 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE-------------KGAP-- 146
Query: 63 SPAPRSGELGLPGAPESSTASAPGEPSPPSPP 94
P R GE G PG P PG P PP PP
Sbjct: 147 GPRGRDGEPGTPGNP-----GPPGPPGPPGPP 173
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 52.8 bits (125), Expect = 8e-07
Identities = 45/129 (34%), Positives = 54/129 (41%), Gaps = 19/129 (14%)
Query: 5 GPHSPGGD-GSAGAGAEEPTP-HEGQAAATGPPSPLHPGAD--ATHPPPPARSPRRPGAP 60
GP P GD G AG E H G G P P P D A+ P P+ PR P P
Sbjct: 1041 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS-GPRGPPGP 1099
Query: 61 SLSPAPRSGELGLPG----------APESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRH 110
+ P+ + G G+PG + E+ A PG P PP PP PGP +
Sbjct: 1100 -VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP-GPPGPGIDMSAFA-- 1155
Query: 111 GLGAGLGGP 119
GLG GP
Sbjct: 1156 GLGPREKGP 1164
Score = 50.8 bits (120), Expect = 3e-06
Identities = 42/127 (33%), Positives = 52/127 (40%), Gaps = 13/127 (10%)
Query: 6 PHSPGGDGSAG-AGAEEPTPHEGQAAATGPPSPLHP-GADATHPPPPARSPRRPGAPSLS 63
P +PG GS G AG G+A A GP P P GA P + PR +
Sbjct: 998 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP---QGPRGDKGEAGE 1054
Query: 64 PAPR--------SGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAG 115
P R +G GLPG P S P+ PS P PGP + G +G+
Sbjct: 1055 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP 1114
Query: 116 LGGPGAR 122
+G PG R
Sbjct: 1115 IGPPGPR 1121
Score = 50.1 bits (118), Expect = 5e-06
Identities = 43/120 (35%), Positives = 48/120 (40%), Gaps = 29/120 (24%)
Query: 3 PFGPHS-PGGDGSAG-AGAEEPTPHEGQAAATGPPSPL----------HPGADATHPPPP 50
P GP PG G G AGA ++GQ GPP P+ PGA P
Sbjct: 253 PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG 312
Query: 51 ARSPR-------RPGAPSLSPAP-----RSGELGLPGAPESS----TASAPGEPSPPSPP 94
AR P PG P SP P G G+PGA S+ A APG P P PP
Sbjct: 313 ARGPEGAQGPRGEPGTPG-SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 371
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/114 (32%), Positives = 47/114 (41%), Gaps = 9/114 (7%)
Query: 9 PGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAP-R 67
PG G +G ++ P G + GPP P+ P PA P R G+P P R
Sbjct: 926 PGLPGPSGEPGKQGAP--GASGDRGPPGPVGPPGLTG----PAGEPGREGSPGADGPPGR 979
Query: 68 SGELGLPG-APESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG 120
G G+ G E+ APG P PP P GP + RG G +G G
Sbjct: 980 DGAAGVKGDRGETGAVGAPGAPGPPGSP-GPAGPTGKQGDRGEAGAQGPMGPSG 1032
Score = 46.6 bits (109), Expect = 6e-05
Identities = 44/152 (28%), Positives = 51/152 (33%), Gaps = 31/152 (20%)
Query: 3 PFGPHSPGGD-GSAGA-GAEEPTPHEGQAAATGPPSPLHPGADATHP------------- 47
P G P GD G G GA P +G+ G P P P P
Sbjct: 58 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117
Query: 48 ---------------PPPARSPRRPGAPSLSPAPRSGELGLPGAPESSTASAPGEPSPPS 92
P PR P P+ +P P+ G G PG P S P P P
Sbjct: 118 FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQ-GFQGNPGEPGEPGVSGPMGPRGPP 176
Query: 93 PPCRRPGPDCRAKSRGRHGLGAGLGGPGARLF 124
P +PG D A G+ G G GAR F
Sbjct: 177 GPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 208
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/128 (31%), Positives = 46/128 (35%), Gaps = 11/128 (8%)
Query: 5 GPH-SPGGDGSAGA----GAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGA 59
GP +PG DG G G P G+ GPP P G+ P R P
Sbjct: 705 GPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA--GSAGARGAPGERGETGPPG 762
Query: 60 PSLSPAPRSGELGLPGAP-ESSTASAPGEPSPPSP--PCRRPGPDCRAKSRGRHGLGAGL 116
P+ P + G PGA E A G+ P P P PGP G G
Sbjct: 763 PAGFAGPPGAD-GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821
Query: 117 GGPGARLF 124
G PGA F
Sbjct: 822 GPPGATGF 829
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/129 (33%), Positives = 50/129 (38%), Gaps = 19/129 (14%)
Query: 9 PGGDGSAGAGAEEPTP-HEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAPR 67
PG G AG E+ P +G + A GPP P P + R G P L P P
Sbjct: 875 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGER-GFPGL-PGP- 931
Query: 68 SGELGLPGAPESS-------TASAPGEPSPPSPPCRR--------PGPDCRAKSRGRHGL 112
SGE G GAP +S PG P P R PG D A +G G
Sbjct: 932 SGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE 991
Query: 113 GAGLGGPGA 121
+G PGA
Sbjct: 992 TGAVGAPGA 1000
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/132 (27%), Positives = 44/132 (33%), Gaps = 38/132 (28%)
Query: 6 PHSPGGDGSAGAGAEEPTP----------HEGQAAATGPPSPLHPGADATHPPPPARS-- 53
P G +G G E+ P +G+ A GPP P P + P S
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595
Query: 54 ---PRRPGAPSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRH 110
P PG P P G+ G+PG A APG P RG
Sbjct: 596 QGLPGPPGPPGEGGKP--GDQGVPG-----EAGAPGLVGP----------------RGER 632
Query: 111 GLGAGLGGPGAR 122
G G PGA+
Sbjct: 633 GFPGERGSPGAQ 644
Score = 39.3 bits (90), Expect = 0.010
Identities = 43/136 (31%), Positives = 49/136 (36%), Gaps = 26/136 (19%)
Query: 9 PGGDGSAGAGAEE-PTPHEGQAAATGP------PSPLHP-------GADATHPPPPARSP 54
PG DG GA E+ +G A A GP P P P GA PP A
Sbjct: 770 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG- 828
Query: 55 RRPGAPS-LSPAPRSGELGLPGAPESSTASAP----GEPSPP----SPPCRRP-GPDCRA 104
PGA + P +G G PG P S P G+ PP P + P GP
Sbjct: 829 -FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 887
Query: 105 KSRGRHGLGAGLGGPG 120
G G G PG
Sbjct: 888 GEPGDDGPSGAEGPPG 903
Score = 38.5 bits (88), Expect = 0.016
Identities = 50/165 (30%), Positives = 57/165 (34%), Gaps = 47/165 (28%)
Query: 5 GPHSPGGD-GSAGA-GAEEPTPHEGQAAATGPPSPL----------------HPGADATH 46
G P G+ G AG GA P EG+ A G P + PG D
Sbjct: 396 GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA 455
Query: 47 PPPPARSPRRP----GAPSLSPAP-RSGELGLPGA-----------PESST--ASAPGE- 87
P A R P G + P R GE GLPGA P+ + APGE
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 515
Query: 88 --PSPPSPPCRR--------PGPDCRAKSRGRHGLGAGLGGPGAR 122
P PP P R PGP G+ G G PG R
Sbjct: 516 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560
Score = 37.7 bits (86), Expect = 0.028
Identities = 42/159 (26%), Positives = 47/159 (29%), Gaps = 43/159 (27%)
Query: 1 MFPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPAR-----SPR 55
M P GP P G AGA P +G G P P P PP +
Sbjct: 134 MGPMGPRGPPGP----AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189
Query: 56 RPG-APSLSPAPRSGELGLPGAP----------------------------ESSTASAPG 86
+PG A P G G PG P ES + G
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249
Query: 87 EPSPPSP-----PCRRPGPDCRAKSRGRHGLGAGLGGPG 120
P P P R GP A +RG G G PG
Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 288
Score = 37.0 bits (84), Expect = 0.048
Identities = 37/121 (30%), Positives = 44/121 (36%), Gaps = 11/121 (9%)
Query: 9 PGGDGSAG-AGAEEPTPHEGQAAATGPPSPLHP----GADATHPPPPARSPR----RPGA 59
PG DG+ G AGA G G P P+ P G P A R +PG
Sbjct: 224 PGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG- 282
Query: 60 PSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGP 119
P+ P P G G PG P + A P+ P GP + G G G P
Sbjct: 283 PAGPPGP-VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP 341
Query: 120 G 120
G
Sbjct: 342 G 342
Score = 35.0 bits (79), Expect = 0.18
Identities = 40/145 (27%), Positives = 48/145 (33%), Gaps = 25/145 (17%)
Query: 3 PFGPHSPGGDGSAG--AGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPR-RPGA 59
P P PG DG AG A E P Q A P +P PG P + GA
Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235
Query: 60 PSL-----------SPAP-----------RSGELGLPGAPESSTASAPGEPSPPSPPCRR 97
P + SP P R+G G GA + P P P P
Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295
Query: 98 PGPDCRAKSRGRHGLGAGLGGPGAR 122
PG ++G G G GA+
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQ 320
Score = 35.0 bits (79), Expect = 0.18
Identities = 34/131 (25%), Positives = 42/131 (32%), Gaps = 19/131 (14%)
Query: 6 PHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPL----------HPGADATHPP------P 49
P PG G G ++ P G+A A G P PGA P P
Sbjct: 599 PGPPGPPGEGGKPGDQGVP--GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 656
Query: 50 PARSPRRPGAPSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGR 109
P+ P+ P G GL G P A+ P GP+ G
Sbjct: 657 GTDGPKGASGPA-GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 715
Query: 110 HGLGAGLGGPG 120
GL +G PG
Sbjct: 716 RGLTGPIGPPG 726
Score = 33.9 bits (76), Expect = 0.40
Identities = 28/92 (30%), Positives = 31/92 (33%), Gaps = 20/92 (21%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSL 62
P G GD G + P +G A GP + GAP
Sbjct: 33 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE-------------KGAP-- 77
Query: 63 SPAPRSGELGLPGAPESSTASAPGEPSPPSPP 94
P R GE G PG P PG P PP PP
Sbjct: 78 GPRGRDGEPGTPGNP-----GPPGPPGPPGPP 104
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 52.4 bits (124), Expect = 1e-06
Identities = 49/158 (31%), Positives = 56/158 (35%), Gaps = 25/158 (15%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSP--LHPGADATHPPPPARSPRRPGAP 60
P P P A A P AAAT PPSP PG A P A P P AP
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAP 187
Query: 61 SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRR--PGPDCRAKSRG---RHGLGA- 114
P P A + P P PP+PP ++ P P + G R G A
Sbjct: 188 PAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAAR 247
Query: 115 ------------GLGGPGARLF-----GWLKERSLGRG 135
G GG G RL G L+E + RG
Sbjct: 248 PVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARG 285
Score = 39.3 bits (90), Expect = 0.010
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 24 PHEGQAAATGPPSPLH-PGADATHPPPPARSPRRPGAPSLSPAPRSGELGLPGAPESSTA 82
P G P +P P A A PPP +P P AP + AP AP ++ A
Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR-------APRAAAA 154
Query: 83 SAPGEPSPPSPPCRRPGP 100
+A +PPSP +PGP
Sbjct: 155 AA---TAPPSPGPAQPGP 169
Score = 37.4 bits (85), Expect = 0.037
Identities = 33/104 (31%), Positives = 40/104 (38%), Gaps = 17/104 (16%)
Query: 18 GAEEPTPHEGQAAATGPPSPLHPGADATHPPP--------PARSPRRPGA-----PSLSP 64
GA P P A + P PPP PAR+PR A PS P
Sbjct: 105 GATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGP 164
Query: 65 A---PRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAK 105
A PR+ AP + A AP +PP+ P R P P A+
Sbjct: 165 AQPGPRAQRAAPLAAPPPAPA-APPAVAPPAGPRRAPPPAVAAR 207
Score = 31.6 bits (70), Expect = 2.0
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 12/79 (15%)
Query: 24 PHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAPRS--------GELGLPG 75
PH+GQ GP PG+ A + G S++ P S G+ LPG
Sbjct: 385 PHQGQDEGRGPA----PGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPG 440
Query: 76 APESSTASAPGEPSPPSPP 94
A + PG PS P
Sbjct: 441 ADGTPFGCPPGRKEKPSDP 459
>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
Length = 540
Score = 52.0 bits (123), Expect = 1e-06
Identities = 47/148 (31%), Positives = 52/148 (35%), Gaps = 34/148 (22%)
Query: 6 PHSPGGDGSAGA-GAEEPTPHEGQAAATGPPSPLHPGADATHPPP-------------PA 51
P PG G GA G P +GQ A GPP P PG PP PA
Sbjct: 156 PGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGP--PGPPGARGPPGDTGKDGPRGAQGPA 213
Query: 52 RSPRRPG-----APSLSPAPRSGELGLPGAP-ESSTASAPGEPSPPSPPCR--------- 96
PG P P P+ GE G+PG + T S PG P P P
Sbjct: 214 GPKGEPGQDGEMGPKGPPGPK-GEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGV 272
Query: 97 --RPGPDCRAKSRGRHGLGAGLGGPGAR 122
PGP RG G G PG +
Sbjct: 273 DGAPGPKGEPGHRGTDGAAGPRGAPGLK 300
Score = 39.3 bits (90), Expect = 0.010
Identities = 37/111 (33%), Positives = 41/111 (36%), Gaps = 30/111 (27%)
Query: 5 GPHSPGG-DGSAGAGAEEPTPHEGQAAATGPPSPLHPGA-----------------DATH 46
GP G DG+ G E H G A GP PG DA
Sbjct: 265 GPRGENGVDGAPGPKGEPG--HRGTDGAAGPRGA--PGLKGEQGDTVVIDYDGRILDALK 320
Query: 47 PPPPARSPRRPGAPSLSPAPRSGELGLPGAP----ESSTASAPGEPSPPSP 93
PP + P PG P + A GELGLPGAP E G+P P P
Sbjct: 321 GPPGPQGP--PGPPGIPGA--KGELGLPGAPGIDGEKGPKGQKGDPGEPGP 367
Score = 34.3 bits (77), Expect = 0.31
Identities = 42/140 (30%), Positives = 48/140 (34%), Gaps = 42/140 (30%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARS-PRRPGAPS 61
P GP PG G GA E P PG D P + P PG
Sbjct: 325 PQGP--PGPPGIPGAKGELGLPGA-------------PGIDGEKGPKGQKGDPGEPGPAG 369
Query: 62 LSPAPRSGELGLPGAP----------ESSTASA----------PGEPSPPSPPCRRPGPD 101
L +GE+GL G P ES++ S PG P PP P PGP
Sbjct: 370 LKG--EAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGP----PGPM 423
Query: 102 CRAKSRGRHGLGAGLGGPGA 121
+G GL G GA
Sbjct: 424 GLQGIQGPKGLDGAKGEKGA 443
>gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo
sapiens]
Length = 459
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 14/116 (12%)
Query: 9 PGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGA--DATHPPPPARSPRRPGAPSLSPAP 66
P G G P AA PSP PG+ AT P RS RR + P
Sbjct: 142 PAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRR------ALQP 195
Query: 67 RSGELGLPGAPESSTASAPGEPSPPSPPCRRPG-PDCRAKSRGRHGLGAGLGGPGA 121
R PGAP ST+ A P+P P RRPG P +++R R LGG A
Sbjct: 196 RHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRE-----LGGSAA 246
Score = 40.4 bits (93), Expect = 0.004
Identities = 34/101 (33%), Positives = 39/101 (38%), Gaps = 14/101 (13%)
Query: 8 SPGGDGSAGAGAEEPTPHEGQAAATGP--PSPLHPGADATH-----PPPPARSP--RRPG 58
SP GS + P A P +P PGA + PPP R P RRPG
Sbjct: 169 SPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPG 228
Query: 59 APSLSPAPRSGELGLPGAPESS-----TASAPGEPSPPSPP 94
AP L R ELG AP + T S P+ PP
Sbjct: 229 APRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPP 269
>gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo
sapiens]
Length = 459
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 14/116 (12%)
Query: 9 PGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGA--DATHPPPPARSPRRPGAPSLSPAP 66
P G G P AA PSP PG+ AT P RS RR + P
Sbjct: 142 PAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRR------ALQP 195
Query: 67 RSGELGLPGAPESSTASAPGEPSPPSPPCRRPG-PDCRAKSRGRHGLGAGLGGPGA 121
R PGAP ST+ A P+P P RRPG P +++R R LGG A
Sbjct: 196 RHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRE-----LGGSAA 246
Score = 40.4 bits (93), Expect = 0.004
Identities = 34/101 (33%), Positives = 39/101 (38%), Gaps = 14/101 (13%)
Query: 8 SPGGDGSAGAGAEEPTPHEGQAAATGP--PSPLHPGADATH-----PPPPARSP--RRPG 58
SP GS + P A P +P PGA + PPP R P RRPG
Sbjct: 169 SPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPG 228
Query: 59 APSLSPAPRSGELGLPGAPESS-----TASAPGEPSPPSPP 94
AP L R ELG AP + T S P+ PP
Sbjct: 229 APRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPP 269
>gi|148529011 coronin, actin binding protein, 2B [Homo sapiens]
Length = 480
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 23/178 (12%)
Query: 159 DSVYLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIR 218
D+ + + T E + GS L + EQT I + K H+ V +I+
Sbjct: 42 DNHFCAVNTRFLAIVTESAGGGSFLVIPLEQT-----GRIEPNYPKVCG--HQGNVLDIK 94
Query: 219 ---FLDNRLFATCSDDTTIALWDL------RKLNTKVCTLHGHTSWVKNIE-YDTNTRLL 268
F+DN + A+CS+DT++ +W++ R + + LHGH+ V +E + T +L
Sbjct: 95 WNPFIDN-IIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNIL 153
Query: 269 VTSGFDGNVIIWDTNRYTEDGCPHKKF-FHTRFLMRMRLTPDCSKMLISTSSGYLLIL 325
++G+D V+IW+ + G P K HT ++ M D S + + L ++
Sbjct: 154 FSAGYDYKVLIWN----LDVGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVI 207
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/106 (36%), Positives = 44/106 (41%), Gaps = 16/106 (15%)
Query: 3 PFGPHSPGGD-GSAGAGAEEPTP-HEGQAAATGPPSPLHPGADATHPPPPARSPRRP-GA 59
P GP P GD G G + H G + GPP P PG+ P A P P G
Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGP--PGSPGEQGPSGASGPAGPRGP 1143
Query: 60 PSLSPAP-RSGELGLPG-----APESSTASA-----PGEPSPPSPP 94
P + AP + G GLPG P T A PG P PP PP
Sbjct: 1144 PGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPP 1189
Score = 50.8 bits (120), Expect = 3e-06
Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 3/115 (2%)
Query: 8 SPGGDGSAG-AGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAP 66
+PG G+ G AG T G A GPP P P P + + PA
Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAG 917
Query: 67 RSGELGLPGAP-ESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPG 120
R GE+G PG P + +PG P P PGP A RG GL G G
Sbjct: 918 RPGEVGPPGPPGPAGEKGSPGADGPAGAP-GTPGPQGIAGQRGVVGLPGQRGERG 971
Score = 49.7 bits (117), Expect = 7e-06
Identities = 48/133 (36%), Positives = 51/133 (38%), Gaps = 23/133 (17%)
Query: 5 GPHSP-GGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGAD-------ATHPP-------- 48
GP P G +G G E P G A A GP +PGAD A P
Sbjct: 356 GPQGPRGSEGPQGVRGEPGPP--GPAGAAGPAG--NPGADGQPGAKGANGAPGIAGAPGF 411
Query: 49 PPARSPRRPGAPSLSPAPRSGELGLPGAPESS-TASAPGEPSPPSPPCRRPGPDCRAKSR 107
P AR P P P P P+ G G PGAP S A GEP P PGP R
Sbjct: 412 PGARGPSGPQGPGGPPGPK-GNSGEPGAPGSKGDTGAKGEPGPVGVQ-GPPGPAGEEGKR 469
Query: 108 GRHGLGAGLGGPG 120
G G G PG
Sbjct: 470 GARGEPGPTGLPG 482
Score = 49.7 bits (117), Expect = 7e-06
Identities = 58/187 (31%), Positives = 67/187 (35%), Gaps = 40/187 (21%)
Query: 9 PGGDGSAGA----GAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSP 64
PG G G GA P +G+A A GPP P P + PA SP G P +
Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGE-QGPAGSPGFQGLPGPAG 650
Query: 65 AP----RSGELGLP---GAPESSTASA----PGE---PSPPSPPCRR-----PGPDCRAK 105
P + GE G+P GAP S A PGE PP P R PG D
Sbjct: 651 PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKG 710
Query: 106 SRGRHGLGAGLGGPGARLFGWLKERSLG--------------RGLFVDPARDNFRTMTSL 151
G G G PG L G ER +G P +D R +T
Sbjct: 711 DAGAPGAPGSQGAPG--LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP 768
Query: 152 YGSIHPA 158
G PA
Sbjct: 769 IGPPGPA 775
Score = 49.7 bits (117), Expect = 7e-06
Identities = 46/146 (31%), Positives = 53/146 (36%), Gaps = 32/146 (21%)
Query: 3 PFGPHSPGGD--GSAGAGAEEPTPHEGQAAATGPPSPL----HPGADATHPPPPARSPRR 56
P GP P G G G P G+ GPP P PGAD PA +P
Sbjct: 894 PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG-----PAGAPGT 948
Query: 57 PGAPSLS--------PAPRSGELGLPGAPESS-------TASAPGEPSPPSPP-----CR 96
PG ++ P R GE G PG P S + A GE PP P
Sbjct: 949 PGPQGIAGQRGVVGLPGQR-GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAG 1007
Query: 97 RPGPDCRAKSRGRHGLGAGLGGPGAR 122
PG R + G G G PGA+
Sbjct: 1008 PPGESGREGAPGAEGSPGRDGSPGAK 1033
Score = 49.3 bits (116), Expect = 9e-06
Identities = 42/124 (33%), Positives = 46/124 (37%), Gaps = 10/124 (8%)
Query: 8 SPGGDGSAGA----GAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLS 63
SPG DG G G P G +GP P P A P P PG +
Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGP-TGARGAPGDRGEPGPPGPAGFA 814
Query: 64 PAPRSGELGLPGAP-ESSTASAPGEPSPPSP--PCRRPGPDCRAKSRGRHGLGAGLGGPG 120
P G G PGA E A A G+ PP P P PGP + G G G PG
Sbjct: 815 GPP--GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872
Query: 121 ARLF 124
A F
Sbjct: 873 ATGF 876
Score = 48.9 bits (115), Expect = 1e-05
Identities = 47/142 (33%), Positives = 51/142 (35%), Gaps = 27/142 (19%)
Query: 3 PFGPHS-------PGGDGSAGA----GAEEPTPHEGQAAATGPPSPLHPGADATHPPPPA 51
P GP PG DG GA GA G A GP P PG PP P
Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG----PPGPK 430
Query: 52 RSPRRPGAP----SLSPAPRSGELGLPGAP----ESSTASAPGEPSP---PSPPCRRPGP 100
+ PGAP G +G+ G P E A GEP P P PP R GP
Sbjct: 431 GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP 490
Query: 101 DCRAKSRGRHGLGAGLGGPGAR 122
R G G+ G G R
Sbjct: 491 GSRG-FPGADGVAGPKGPAGER 511
Score = 48.9 bits (115), Expect = 1e-05
Identities = 54/171 (31%), Positives = 58/171 (33%), Gaps = 55/171 (32%)
Query: 6 PHSPGGDGSAGAGAEE----------PTPHEGQAAATGPPSPL----------------H 39
P +PG G GA E P EG+ A G P P
Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495
Query: 40 PGADATHPPP-PA--RSPRRPGAPSLSP--APRSGELGLP------GAPES--------- 79
PGAD P PA R P P SP A R GE GLP G+P S
Sbjct: 496 PGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGP 555
Query: 80 -STASAPGEPSPPSPPCRR--------PGPDCRAKSRGRHGLGAGLGGPGA 121
A G P PP PP R PGP A G+ G G PGA
Sbjct: 556 PGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA 606
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/146 (34%), Positives = 58/146 (39%), Gaps = 31/146 (21%)
Query: 5 GPHSPGGD-GSAGAGAEEPTPHE-GQAAATGPP-------SPLHPGADA-THPPPPARSP 54
GP P G+ GS G + +P E G+ G P SP PG D T PP PA
Sbjct: 503 GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD 562
Query: 55 RRPGAPSLSPAP-RSGELGLPG----APESSTASAPGEPSPPSP--PCRR---------P 98
RPG P A ++G +G PG A E A G P PP P + P
Sbjct: 563 GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622
Query: 99 GPDCRAKSRGRHGLGA-----GLGGP 119
GP A RG G GL GP
Sbjct: 623 GPAGPAGERGEQGPAGSPGFQGLPGP 648
Score = 47.0 bits (110), Expect = 5e-05
Identities = 42/127 (33%), Positives = 49/127 (38%), Gaps = 12/127 (9%)
Query: 3 PFGPHSPGGD-GSAGAGAEEPTP-HEGQAAATGPPSPLHPGADATHPPPPARSPRRPGA- 59
P GP PGG G G E P +G A G P P+ PP PA + GA
Sbjct: 417 PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV----GVQGPPGPAGEEGKRGAR 472
Query: 60 ----PSLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAG 115
P+ P P GE G PG+ A P P+ PGP S G G
Sbjct: 473 GEPGPTGLPGP-PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531
Query: 116 LGGPGAR 122
G PGA+
Sbjct: 532 AGLPGAK 538
Score = 47.0 bits (110), Expect = 5e-05
Identities = 45/140 (32%), Positives = 49/140 (35%), Gaps = 34/140 (24%)
Query: 9 PGGDGSAGAGAEE-PTPHEGQAAATGPPSPLHP-------------GADATHPPPPARSP 54
PG DG GA E +G A GP P P GA + PP A
Sbjct: 817 PGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG- 875
Query: 55 RRPGAPS-LSPAPRSGELGLPGAP-------------ESSTASAPGEPSPPSPPCRRPGP 100
PGA + P SG G PG P E+ A PGE PP P PGP
Sbjct: 876 -FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP----PGP 930
Query: 101 DCRAKSRGRHGLGAGLGGPG 120
S G G G PG
Sbjct: 931 AGEKGSPGADGPAGAPGTPG 950
Score = 46.6 bits (109), Expect = 6e-05
Identities = 44/135 (32%), Positives = 50/135 (37%), Gaps = 33/135 (24%)
Query: 6 PHSPGGDGSAGA-------------GAEEPTPHEGQAAATGPPSPLHPGADATHPPPPAR 52
P SPG +G+ G GA P G ATG P PG P PA
Sbjct: 289 PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP--PG-----PTGPAG 341
Query: 53 SPRRPGAPSLSPAPRSGELGLPGAPESSTA--SAPGEPSPPSP-----PCRRPGPDCRAK 105
P PGA GE G P P S GEP PP P P PG D +
Sbjct: 342 PPGFPGA-----VGAKGEAG-PQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPG 395
Query: 106 SRGRHGLGAGLGGPG 120
++G +G G PG
Sbjct: 396 AKGANGAPGIAGAPG 410
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/130 (31%), Positives = 47/130 (36%), Gaps = 12/130 (9%)
Query: 3 PFGPHSPGGDGSAGA-GAEEPTPHEGQAAATGPPSPLHP-GADATHPPPPARSPRRPGAP 60
P GP PG G+ GA G P G TGP P P G P + PR
Sbjct: 1041 PAGP--PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGE 1098
Query: 61 SLSPAPR--------SGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGL 112
+ R SG G PG P S P S P+ P PG G +GL
Sbjct: 1099 TGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGL 1158
Query: 113 GAGLGGPGAR 122
+G PG R
Sbjct: 1159 PGPIGPPGPR 1168
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/119 (34%), Positives = 48/119 (40%), Gaps = 6/119 (5%)
Query: 3 PFGPHS-PGGDGSAG-AGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAP 60
P GP PG G+ G AG + P EG G P P P A A P + +PGA
Sbjct: 339 PAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP-AGAAGPAGNPGADGQPGAK 397
Query: 61 SLSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGP 119
+ AP G G PG P + S P P P P G S+G G G GP
Sbjct: 398 GANGAP--GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTG-AKGEPGP 453
Score = 44.7 bits (104), Expect = 2e-04
Identities = 44/137 (32%), Positives = 51/137 (37%), Gaps = 21/137 (15%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPP-SPLHPGADATHPPPPAR---SPRRPG 58
P GP P G A EP P G A GPP + PGA A+ P P
Sbjct: 786 PSGPAGPTGARGAPGDRGEPGP-PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844
Query: 59 APSLSPAPRSGELGLPGA--------PESSTA--SAPGEPSPPSP-----PCRRPGPDCR 103
P+ P P G +G PGA P +T A G PP P P PGP +
Sbjct: 845 GPAGPPGP-IGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGK 903
Query: 104 AKSRGRHGLGAGLGGPG 120
+G G G PG
Sbjct: 904 EGGKGPRGETGPAGRPG 920
Score = 42.7 bits (99), Expect = 9e-04
Identities = 50/158 (31%), Positives = 53/158 (33%), Gaps = 48/158 (30%)
Query: 12 DGSAGAGAEEPTPHEGQAAATGPPSPL----HPGADA-------THPPPPARSPRRPG-- 58
DGS +E T EG TGP P PG D PP P P PG
Sbjct: 97 DGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLG 156
Query: 59 ---APSLS---------------PAPRSGELGLPGAPES-------STASAPGEP----- 88
AP LS P SG GLPG P + PGEP
Sbjct: 157 GNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGP 216
Query: 89 ----SPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPGAR 122
PP PP + G D A GR G G GAR
Sbjct: 217 MGPRGPPGPPGKN-GDDGEAGKPGRPGERGPPGPQGAR 253
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/128 (32%), Positives = 47/128 (36%), Gaps = 18/128 (14%)
Query: 3 PFGPHSPGGD-GSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPS 61
P GP P G G G E P G+ GPP P A P A P G
Sbjct: 216 PMGPRGPPGPPGKNGDDGEAGKP--GRPGERGPPGP----QGARGLPGTAGLPGMKGHRG 269
Query: 62 LS-------PAPRSGELGLPGAPESSTASAPGEPSPPSPPCR--RPGPDCRAKSRGRHGL 112
S A +G G PG+P + APG+ P P RPG A +RG G
Sbjct: 270 FSGLDGAKGDAGPAGPKGEPGSPGEN--GAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327
Query: 113 GAGLGGPG 120
G PG
Sbjct: 328 TGAAGPPG 335
Score = 40.4 bits (93), Expect = 0.004
Identities = 37/114 (32%), Positives = 44/114 (38%), Gaps = 21/114 (18%)
Query: 9 PGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPAR--SPRRPGAPSLS-PA 65
PG G +GA E P GPP P ++ P SP R G+P
Sbjct: 982 PGKQGPSGASGERGPP-----GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR 1036
Query: 66 PRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGP 119
+G G PGAP APG P P GP ++ RG G AG GP
Sbjct: 1037 GETGPAGPPGAP-----GAPGAPGP-------VGPAGKSGDRGETG-PAGPAGP 1077
Score = 39.7 bits (91), Expect = 0.007
Identities = 39/121 (32%), Positives = 45/121 (37%), Gaps = 31/121 (25%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPS- 61
P SPG DGS GA +G TGP P PGA P PGAP
Sbjct: 1018 PGAEGSPGRDGSPGA--------KGDRGETGPAGP--PGA-----------PGAPGAPGP 1056
Query: 62 LSPAPRSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPGA 121
+ PA +SG+ G G P P+ P P GP RG G G G
Sbjct: 1057 VGPAGKSGDRGETG---------PAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107
Query: 122 R 122
+
Sbjct: 1108 K 1108
Score = 36.6 bits (83), Expect = 0.062
Identities = 38/141 (26%), Positives = 47/141 (33%), Gaps = 26/141 (18%)
Query: 6 PHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHP-GADATHPPPPAR-------SPRRP 57
P G G +GA E P G+ GPP P P GA+ A+ +P
Sbjct: 664 PGDLGAPGPSGARGERGFP--GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721
Query: 58 GAPSLS-----------PAPR-----SGELGLPGAPESSTASAPGEPSPPSPPCRRPGPD 101
GAP L P P+ +G G G+P P P P PG
Sbjct: 722 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK 781
Query: 102 CRAKSRGRHGLGAGLGGPGAR 122
+ G G G PG R
Sbjct: 782 GESGPSGPAGPTGARGAPGDR 802
Score = 33.9 bits (76), Expect = 0.40
Identities = 24/61 (39%), Positives = 26/61 (42%), Gaps = 6/61 (9%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADA--THPPPPARSPRRPGAP 60
P GP P GSAGA ++ G GPP P DA PP P P PG P
Sbjct: 1137 PAGPRGP--PGSAGAPGKDGL--NGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP 1192
Query: 61 S 61
S
Sbjct: 1193 S 1193
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/128 (35%), Positives = 50/128 (39%), Gaps = 15/128 (11%)
Query: 3 PFGPHSPGGDG--SAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARS--PRRPG 58
P PH+ G + G GA P P AA PP P P A PPPP R P P
Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSV-AVPPPPPNRMYPPPPPA 349
Query: 59 APSLSPAPRSGELGLPGAPESSTAS---APGEPSPPSPPCRRPGPDCRAKSRGRHGLGAG 115
PS +P+ G P P S AP P PP PP P P S G H +
Sbjct: 350 LPSSAPS------GPPPPPPSVLGVGPVAPPPPPPPPPP-PGPPPPPGLPSDGDHQVPTT 402
Query: 116 LGGPGARL 123
G A L
Sbjct: 403 AGNKAALL 410
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/79 (36%), Positives = 32/79 (40%), Gaps = 13/79 (16%)
Query: 22 PTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAPRSGELGLPGAPESST 81
P P G GPP P P ++ PPPPAR P P S AP + AP
Sbjct: 280 PPPSRG-----GPPPPPPPPHNSGPPPPPARGRGAPPPPP-SRAPTA-------APPPPP 326
Query: 82 ASAPGEPSPPSPPCRRPGP 100
S P PP PP R P
Sbjct: 327 PSRPSVAVPPPPPNRMYPP 345
Score = 36.2 bits (82), Expect = 0.082
Identities = 27/83 (32%), Positives = 31/83 (37%), Gaps = 8/83 (9%)
Query: 18 GAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSLSPAPRSGELGLPGAP 77
G E +E + A PP P G PPPP S G P P P G P P
Sbjct: 263 GGVEAVKNELRRQAPPPPPPSR-GGPPPPPPPPHNS----GPP---PPPARGRGAPPPPP 314
Query: 78 ESSTASAPGEPSPPSPPCRRPGP 100
+ +AP P P P P P
Sbjct: 315 SRAPTAAPPPPPPSRPSVAVPPP 337
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 51.2 bits (121), Expect = 2e-06
Identities = 44/127 (34%), Positives = 49/127 (38%), Gaps = 17/127 (13%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSL 62
P GP P G G GA+ P G + A GPP P PP P P G L
Sbjct: 1584 PPGPPGPAG----GPGAKGPRGERGISGAIGPPGP----RGDIGPPGPQGPPGPQGPNGL 1635
Query: 63 S-PAPR-----SGELGLPGAP-ESSTASAPGEPSPPSPPCRR--PGPDCRAKSRGRHGLG 113
S P + G+ G PG P + T PG P P PP R G D RG G
Sbjct: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 1695
Query: 114 AGLGGPG 120
G PG
Sbjct: 1696 GSPGSPG 1702
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/101 (31%), Positives = 35/101 (34%), Gaps = 24/101 (23%)
Query: 22 PTPHEGQAAATGPPSPLHP--GADATHPPPPARSPRRPGAPSLSPAP------------- 66
P ++ GPP P P A A P P P PG P + P
Sbjct: 1767 PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG 1826
Query: 67 --RSGELGLPGAPESSTASAPGEPS------PPSPPCRRPG 99
SG GLPG P S G P PP PP RPG
Sbjct: 1827 TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPP-GRPG 1866
Score = 37.0 bits (84), Expect = 0.048
Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 5/88 (5%)
Query: 2 FPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPS 61
FP P G G G E+ G + G P P P ++ PP + R P P
Sbjct: 1803 FPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPP 1862
Query: 62 LSPAPRSGELGLPGAP----ESSTASAP 85
P SG G PG P S AS P
Sbjct: 1863 GRPG-NSGIRGPPGPPGYCDSSQCASIP 1889
Score = 35.0 bits (79), Expect = 0.18
Identities = 52/206 (25%), Positives = 58/206 (28%), Gaps = 78/206 (37%)
Query: 3 PFGPHSPGG---------DGSAGAGAEEPTP-HEGQAAATGPPSPLHPGADATH------ 46
P GP P G G G E P G GPP P+ P D
Sbjct: 1626 PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA 1685
Query: 47 -----PPPPARSPRRPGAPSLSPAP-RSGELGLPGAPE---------------------- 78
PP P SP PG S P + G+ G PG
Sbjct: 1686 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 1745
Query: 79 -------------------------SSTASAPGEPSPPSPPCR-----RPGPDCRAKSRG 108
S+ + PG P PP PP PGP R G
Sbjct: 1746 QVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPG 1805
Query: 109 RHGLGAGLGGPGAR-LFGWLKERSLG 133
G+ G PG R L G ER G
Sbjct: 1806 TPGM---QGPPGERGLPGEKGERGTG 1828
Score = 31.2 bits (69), Expect = 2.6
Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Query: 67 RSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPGAR 122
R E P P S T + PP PP GP + RG G+ +G PG R
Sbjct: 1562 RRDEGKCPAFPNSCTCTQDSV-GPPGPPGPAGGPGAKGP-RGERGISGAIGPPGPR 1615
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 51.2 bits (121), Expect = 2e-06
Identities = 44/127 (34%), Positives = 49/127 (38%), Gaps = 17/127 (13%)
Query: 3 PFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPSL 62
P GP P G G GA+ P G + A GPP P PP P P G L
Sbjct: 2748 PPGPPGPAG----GPGAKGPRGERGISGAIGPPGP----RGDIGPPGPQGPPGPQGPNGL 2799
Query: 63 S-PAPR-----SGELGLPGAP-ESSTASAPGEPSPPSPPCRR--PGPDCRAKSRGRHGLG 113
S P + G+ G PG P + T PG P P PP R G D RG G
Sbjct: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859
Query: 114 AGLGGPG 120
G PG
Sbjct: 2860 GSPGSPG 2866
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/101 (31%), Positives = 35/101 (34%), Gaps = 24/101 (23%)
Query: 22 PTPHEGQAAATGPPSPLHP--GADATHPPPPARSPRRPGAPSLSPAP------------- 66
P ++ GPP P P A A P P P PG P + P
Sbjct: 2931 PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG 2990
Query: 67 --RSGELGLPGAPESSTASAPGEPS------PPSPPCRRPG 99
SG GLPG P S G P PP PP RPG
Sbjct: 2991 TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPP-GRPG 3030
Score = 37.0 bits (84), Expect = 0.048
Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 5/88 (5%)
Query: 2 FPFGPHSPGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGADATHPPPPARSPRRPGAPS 61
FP P G G G E+ G + G P P P ++ PP + R P P
Sbjct: 2967 FPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPP 3026
Query: 62 LSPAPRSGELGLPGAP----ESSTASAP 85
P SG G PG P S AS P
Sbjct: 3027 GRPG-NSGIRGPPGPPGYCDSSQCASIP 3053
Score = 35.0 bits (79), Expect = 0.18
Identities = 52/206 (25%), Positives = 58/206 (28%), Gaps = 78/206 (37%)
Query: 3 PFGPHSPGG---------DGSAGAGAEEPTP-HEGQAAATGPPSPLHPGADATH------ 46
P GP P G G G E P G GPP P+ P D
Sbjct: 2790 PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA 2849
Query: 47 -----PPPPARSPRRPGAPSLSPAP-RSGELGLPGAPE---------------------- 78
PP P SP PG S P + G+ G PG
Sbjct: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 2909
Query: 79 -------------------------SSTASAPGEPSPPSPPCR-----RPGPDCRAKSRG 108
S+ + PG P PP PP PGP R G
Sbjct: 2910 QVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPG 2969
Query: 109 RHGLGAGLGGPGAR-LFGWLKERSLG 133
G+ G PG R L G ER G
Sbjct: 2970 TPGM---QGPPGERGLPGEKGERGTG 2992
Score = 31.2 bits (69), Expect = 2.6
Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Query: 67 RSGELGLPGAPESSTASAPGEPSPPSPPCRRPGPDCRAKSRGRHGLGAGLGGPGAR 122
R E P P S T + PP PP GP + RG G+ +G PG R
Sbjct: 2726 RRDEGKCPAFPNSCTCTQDSV-GPPGPPGPAGGPGAKGP-RGERGISGAIGPPGPR 2779
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,133,016
Number of Sequences: 37866
Number of extensions: 1679119
Number of successful extensions: 29516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 564
Number of HSP's successfully gapped in prelim test: 1975
Number of HSP's that attempted gapping in prelim test: 13524
Number of HSP's gapped (non-prelim): 11578
length of query: 559
length of database: 18,247,518
effective HSP length: 107
effective length of query: 452
effective length of database: 14,195,856
effective search space: 6416526912
effective search space used: 6416526912
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.