Guide to the Human Genome
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Search of human proteins with 110611233

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor
[Homo sapiens]
         (1336 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...  2848   0.0  
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...  2776   0.0  
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...  2775   0.0  
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]        780   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      552   e-157
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     547   e-155
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     545   e-155
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   543   e-154
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   541   e-153
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   540   e-153
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               536   e-152
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   533   e-151
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   533   e-151
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   533   e-151
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   530   e-150
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   530   e-150
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   528   e-149
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      527   e-149
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   524   e-148
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    523   e-148
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   523   e-148
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        514   e-145
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   514   e-145
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   512   e-144
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   512   e-144
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   512   e-144
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   512   e-144
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     504   e-142
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         504   e-142
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              490   e-138

>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1336

 Score = 2848 bits (7382), Expect = 0.0
 Identities = 1336/1336 (100%), Positives = 1336/1336 (100%)

Query: 1    MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTD 60
            MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTD
Sbjct: 1    MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTD 60

Query: 61   DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL 120
            DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL
Sbjct: 61   DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL 120

Query: 121  LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC 180
            LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC
Sbjct: 121  LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC 180

Query: 181  EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE 240
            EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE
Sbjct: 181  EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE 240

Query: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300
            GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE
Sbjct: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300

Query: 301  EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 360
            EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP
Sbjct: 301  EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 360

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 420
            CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG
Sbjct: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 420

Query: 421  PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480
            PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL
Sbjct: 421  PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480

Query: 481  EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540
            EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP
Sbjct: 481  EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540

Query: 541  GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 600
            GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP
Sbjct: 541  GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 600

Query: 601  GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG 660
            GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG
Sbjct: 601  GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG 660

Query: 661  VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG 720
            VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG
Sbjct: 661  VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG 720

Query: 721  SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 780
            SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ
Sbjct: 721  SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 780

Query: 781  KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 840
            KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG
Sbjct: 781  KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 840

Query: 841  PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900
            PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD
Sbjct: 841  PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900

Query: 901  FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI 960
            FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI
Sbjct: 901  FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESI 960

Query: 961  RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT 1020
            RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT
Sbjct: 961  RGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT 1020

Query: 1021 MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1080
            MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT
Sbjct: 1021 MGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1080

Query: 1081 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY 1140
            DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY
Sbjct: 1081 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSY 1140

Query: 1141 VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR 1200
            VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR
Sbjct: 1141 VHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFR 1200

Query: 1201 AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD 1260
            AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD
Sbjct: 1201 AFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKD 1260

Query: 1261 VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH 1320
            VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH
Sbjct: 1261 VLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHH 1320

Query: 1321 AYIVLCIENSFMTASK 1336
            AYIVLCIENSFMTASK
Sbjct: 1321 AYIVLCIENSFMTASK 1336


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1516

 Score = 2776 bits (7197), Expect = 0.0
 Identities = 1304/1316 (99%), Positives = 1304/1316 (99%)

Query: 21   PLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA 80
            P   L G        ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA
Sbjct: 201  PWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVA 260

Query: 81   RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT 140
            RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT
Sbjct: 261  RYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYT 320

Query: 141  EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG 200
            EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG
Sbjct: 321  EPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPG 380

Query: 201  AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE 260
            AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE
Sbjct: 381  AGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARE 440

Query: 261  LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS 320
            LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS
Sbjct: 441  LLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVS 500

Query: 321  TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 380
            TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP
Sbjct: 501  TWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 560

Query: 381  ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP 440
            ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP
Sbjct: 561  ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDP 620

Query: 441  GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 500
            GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG
Sbjct: 621  GVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 680

Query: 501  LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE 560
            LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE
Sbjct: 681  LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE 740

Query: 561  AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP 620
            AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP
Sbjct: 741  AGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGP 800

Query: 621  FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 680
            FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK
Sbjct: 801  FWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPK 860

Query: 681  GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740
            GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP
Sbjct: 861  GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 920

Query: 741  AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800
            AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG
Sbjct: 921  AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 980

Query: 801  YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV 860
            YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV
Sbjct: 981  YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNV 1040

Query: 861  FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 920
            FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ
Sbjct: 1041 FAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 1100

Query: 921  KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR 980
            KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR
Sbjct: 1101 KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGR 1160

Query: 981  QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV 1040
            QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV
Sbjct: 1161 QGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQV 1220

Query: 1041 HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY 1100
            HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY
Sbjct: 1221 HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPY 1280

Query: 1101 PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ 1160
            PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ
Sbjct: 1281 PRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQ 1340

Query: 1161 PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA 1220
            PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA
Sbjct: 1341 PVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRA 1400

Query: 1221 AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG 1280
            AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG
Sbjct: 1401 AVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNG 1460

Query: 1281 RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1336
            RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK
Sbjct: 1461 RRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1516



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 49/183 (26%), Positives = 60/183 (32%), Gaps = 31/183 (16%)

Query: 381 ALQTVPGPQGP-PGPPGRDGT---------------PGRDGEPGDPGEDGKPGDTGPQGF 424
           A  T+P PQGP P  P  D T               PG    P +  EDG+   T  +  
Sbjct: 41  AATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAES- 99

Query: 425 PGTPGD--VGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEA 482
           P  P +   G   +  +   G R          P     R + L      G        A
Sbjct: 100 PDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGP------LA 153

Query: 483 LRGPRGFPGPPGPPGVP--GLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540
           L GP   P   G    P  G+P  PG     +  +P P   P   GR   P    L GP 
Sbjct: 154 LAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP----LTGPS 209

Query: 541 GPP 543
            PP
Sbjct: 210 VPP 212


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 2775 bits (7193), Expect = 0.0
 Identities = 1301/1301 (100%), Positives = 1301/1301 (100%)

Query: 36   ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLL 95
            ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLL
Sbjct: 451  ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLL 510

Query: 96   FHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRL 155
            FHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRL
Sbjct: 511  FHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRL 570

Query: 156  PAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDK 215
            PAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDK
Sbjct: 571  PAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDK 630

Query: 216  FQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLP 275
            FQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLP
Sbjct: 631  FQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLP 690

Query: 276  APPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKE 335
            APPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKE
Sbjct: 691  APPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKE 750

Query: 336  GGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPP 395
            GGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPP
Sbjct: 751  GGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPP 810

Query: 396  GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG 455
            GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG
Sbjct: 811  GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG 870

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
            PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV
Sbjct: 871  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 930

Query: 516  PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575
            PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP
Sbjct: 931  PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 990

Query: 576  AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPP 635
            AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPP
Sbjct: 991  AGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPP 1050

Query: 636  GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 695
            GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD
Sbjct: 1051 GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 1110

Query: 696  GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS 755
            GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS
Sbjct: 1111 GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS 1170

Query: 756  PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG 815
            PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG
Sbjct: 1171 PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG 1230

Query: 816  MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN 875
            MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN
Sbjct: 1231 MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN 1290

Query: 876  QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS 935
            QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS
Sbjct: 1291 QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS 1350

Query: 936  SLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSF 995
            SLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSF
Sbjct: 1351 SLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSF 1410

Query: 996  PGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQE 1055
            PGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQE
Sbjct: 1411 PGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQE 1470

Query: 1056 ELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRA 1115
            ELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRA
Sbjct: 1471 ELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRA 1530

Query: 1116 DDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGG 1175
            DDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGG
Sbjct: 1531 DDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGG 1590

Query: 1176 MRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPS 1235
            MRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPS
Sbjct: 1591 MRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPS 1650

Query: 1236 WEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEA 1295
            WEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEA
Sbjct: 1651 WEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEA 1710

Query: 1296 PSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1336
            PSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK
Sbjct: 1711 PSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1751



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 74/301 (24%), Positives = 93/301 (30%), Gaps = 45/301 (14%)

Query: 381 ALQTVPGPQGP-PGPPGRDGT---------------PGRDGEPGDPGEDGKPGDTGPQGF 424
           A  T+P PQGP P  P  D T               PG    P +  EDG+   T  +  
Sbjct: 41  AATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAES- 99

Query: 425 PGTPGD--VGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEA 482
           P  P +   G   +  +   G R          P     R + L      G        A
Sbjct: 100 PDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGP------LA 153

Query: 483 LRGPRGFPGPPGPPGVP--GLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540
           L GP   P   G    P  G+P  PG     +  +P P   P   GR   P    L GP 
Sbjct: 154 LAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP----LTGPS 209

Query: 541 GPPGREGPP------GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA---PGPA 591
            PP   G        G     GSL +  + G   +  AP     R +  L      P   
Sbjct: 210 VPPPSSGRASLSSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVM 269

Query: 592 GPPGPPGPPGPPGPGLPAGFDD-----MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGV 646
           G  G    P     GLP          +    G + S   ++ GP        L  DP  
Sbjct: 270 GSLGKHAAPSAFSSGLPGALSQVAVTTLTRDSGAWVSHVANSVGPGLANNSALLGADPEA 329

Query: 647 P 647
           P
Sbjct: 330 P 330



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 85/361 (23%), Positives = 106/361 (29%), Gaps = 51/361 (14%)

Query: 266 TGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVST---- 321
           T  A  P  P PP   +  L  G  T  S       +  +A +GA+ L  +  + +    
Sbjct: 71  TEPATAPGSPEPP---SELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQL 127

Query: 322 WDGSVRTPGGRVKEGGLKGQKGEPGVP-GPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP 380
           W+ +V T      E   + +      P GP   AGP  +P   G    P    P  P   
Sbjct: 128 WNDTVPT------ESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAH 181

Query: 381 ALQTVPGPQGPPGPPGRDGTPGRDGEPGDP--GEDGKPGDTGPQGFPGTPGDVGPKGDKG 438
             +    P   P PP         G P  P  G    P  +G        G   P G   
Sbjct: 182 TTEAGTLPAPTPSPPSL-------GRPWAPLTGPSVPPPSSGRASLSSLLGGAPPWGSLQ 234

Query: 439 DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGV 498
           DP      P           P  R        +     G          G PG      V
Sbjct: 235 DPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPGALSQVAV 294

Query: 499 PGLPGEPGRF--GVNSSDVPGPAGLPGVPGR--EGPPGFPGLPGPPGPPGREGPPGRTGQ 554
             L  + G +   V +S  PG A    + G   E P G   LP PP  P      G  G 
Sbjct: 295 TTLTRDSGAWVSHVANSVGPGLANNSALLGADPEAPAG-RCLPLPPSLP----VCGHLG- 348

Query: 555 KGSLGEAGAPGH-KGSKGAPGPAGARGESGLAGA--------------PGPAGPPGPPGP 599
              +     P H     G    AGAR   GL                   P G   PP P
Sbjct: 349 ---ISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAP 405

Query: 600 P 600
           P
Sbjct: 406 P 406



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 74/299 (24%), Positives = 95/299 (31%), Gaps = 56/299 (18%)

Query: 589 GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGP-PGLPGLKGDPGVP 647
           G   P   PG P PP   L  G D           T  SA+ P  P   + G+    G  
Sbjct: 69  GSTEPATAPGSPEPPSELLEDGQD-----------TPTSAESPDAPEENIAGV----GAE 113

Query: 648 GLPGAKG-----EVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGL 702
            L  AKG     ++  D VP    L   E +   + P G     G    P ++G      
Sbjct: 114 ILNVAKGIRSFVQLWNDTVP-TESLARAETLV-LETPVGPLALAGPSSTPQENGTTLWPS 171

Query: 703 PGPPGPPGPVVYVSEQDGSVLSVPGPE--GRPGFAGFPGPAGPKGNLGSKGERGSPGPKG 760
            G P  PG   + +E        P P   GRP +A   GP+ P     S G        G
Sbjct: 172 RGIPSSPG--AHTTEAGTLPAPTPSPPSLGRP-WAPLTGPSVPP---PSSGRASLSSLLG 225

Query: 761 EKGEPGSIFSPDGGALGPAQKGAKGE--------------PGFRGPPGPYGRPGYKGEIG 806
                GS+  PD   L PA      +              P   G  G +  P      G
Sbjct: 226 GAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSS-G 284

Query: 807 FPGRPGRPGMNGLKGEKGE----------PGDASLGFGMRGMPGPPGPPGPPGPPGTPV 855
            PG   +  +  L  + G           PG A+    +   P  P     P PP  PV
Sbjct: 285 LPGALSQVAVTTLTRDSGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPV 343


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score =  780 bits (2015), Expect = 0.0
 Identities = 536/1474 (36%), Positives = 690/1474 (46%), Gaps = 254/1474 (17%)

Query: 15   LLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDA 74
            LL V  PL  +   R A+    +    + L QL+G P P  V+         AY FGP A
Sbjct: 16   LLSVSTPLPAVTQTRGATETASQ--GHLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGA 73

Query: 75   NSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQD 134
            N G+ AR   PS FFRDF++   ++P++   GVLFAITD+ Q ++ LG++LSGV+DGHQ 
Sbjct: 74   NVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQR 133

Query: 135  ISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRG 194
            I L YTEPG+  +  AA+F +P    +W   A+ V G  V L V+CEE  R+P  RSS+ 
Sbjct: 134  IILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQA 193

Query: 195  LELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSG 254
            L  E  AG+F+  AG    ++F G + +L V  DP+     C  EE      ASG++ SG
Sbjct: 194  LAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESS----ASGET-SG 248

Query: 255  LGDA---RELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQ 311
            L +A    E+L   T     P+     P+ TPP       +   S E   + T+ +    
Sbjct: 249  LQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMS 308

Query: 312  TLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371
             +  S        S +   G +    L+G     G P     +G      +     L   
Sbjct: 309  IIQHS--------SPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAAT 360

Query: 372  VS-----PLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG--PQGF 424
             +     P+  AG A +    P G P        P     PG   E+          +  
Sbjct: 361  AAGLAEVPISTAGEA-EASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEAL 419

Query: 425  PGTPGDVGPKG--------DKGDPGVGERGPPGPQGPPG--PPGPSFRHDKLTFIDMEGS 474
               PG+V   G              +GE    GP           +      TF D E S
Sbjct: 420  ASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEAS 479

Query: 475  GFGGD----LEALRGPR------------------------------GFPGPPGPPGVPG 500
            G   D    L A   P                               G P P GPP +P 
Sbjct: 480  GVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPP-LPL 538

Query: 501  LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG-----LPGPPGPPGREGPPGRTGQK 555
                P R+       P      G+ G+ GP G  G     LPGPP P G  GP      +
Sbjct: 539  PTVAPERW-----ITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAE 593

Query: 556  GSLGEAGAPGHKGS----------KGAPGPAGARGESGLAGAPG------PAGPPGPPGP 599
            GS    G+    GS          +G PGP G  G  G+ G PG      P G PG  GP
Sbjct: 594  GSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGP 653

Query: 600  PGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 659
             G PGP  P G   ++G+ G      +   G +GP G  G KGDPG  GLPG  G+ G  
Sbjct: 654  AGEPGPPGPEGQPGVDGATG--LPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQA 711

Query: 660  GVPGFPGLPGREGIAGPQGP----------------------------------KGDRGS 685
            G PG  G PG  G  GP GP                                  KG++G 
Sbjct: 712  GPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGD 771

Query: 686  RGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSV-------------LSVPGPEGRP 732
            RG KG+ G DG    G PGP GPPG +  +S    ++             +  PGP+G P
Sbjct: 772  RGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLP 831

Query: 733  GFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQK--GAKGEPGFR 790
            G  GFPGP GPKG+ G  G  G  G +GEKGEPG+I + D     P ++  G KGEPG  
Sbjct: 832  GLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDI----PLERLMGKKGEPGMH 887

Query: 791  GPPGPYGR---PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGP 847
            G PGP G    PG+KGE G PGRPGRPG+NGLKG KG+PG       M+G PG PGPPGP
Sbjct: 888  GAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-----MQGPPGLPGPPGP 942

Query: 848  PGPPGTPVYDSNVF------------AESSRPGPP---------GLPGNQGPPGPKGAKG 886
            PGPPG  +                   +++ PG P         G  G+ G PG KG KG
Sbjct: 943  PGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKG 1002

Query: 887  EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSSLPGPPGPP 944
            + G  GPPG  P D   L   +   KG+ GD G KGE+GE G   G F  S  PG PG P
Sbjct: 1003 DQGAQGPPGP-PLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNP 1061

Query: 945  GPRGYPG--IPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQT 1002
            GP G  G  + GP+G      PG PG  GPPG G  G  GPPGPPGPPGPP+  G     
Sbjct: 1062 GPAGQKGETVVGPQGP-----PGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGA---A 1113

Query: 1003 ISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQ 1062
            +++PGPPGPPG PG PG+      V  ++    ML + H V EG  I++ +  E ++RV+
Sbjct: 1114 VALPGPPGPPGQPGLPGSRNL---VTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVR 1170

Query: 1063 NGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASP 1122
            +G++K+QL    P+P        A  PP   L  SNP+                      
Sbjct: 1171 DGWKKLQLGELIPIP--------ADSPPPPAL-SSNPHQL-------------------- 1201

Query: 1123 PRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGA 1182
              LP P P   A +                       +P LHL ALN P SG +R    A
Sbjct: 1202 --LPPPNPISSANYE----------------------KPALHLAALNMPFSGDIR----A 1233

Query: 1183 DFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSG 1242
            DFQCF+QARA GL  T+RAFLSS LQDL +IVR+A+R ++PIVNLK ++LF +W+++FSG
Sbjct: 1234 DFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNWDSIFSG 1293

Query: 1243 SEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQA 1302
              G       I+SFDG+D++  P+WPQK +WHGS P+G RL ++YCE WRT   + TG A
Sbjct: 1294 HGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLA 1353

Query: 1303 SSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1336
            S L  G++L Q A SC +  IVLCIENSFMT ++
Sbjct: 1354 SPLSTGKILDQKAYSCANRLIVLCIENSFMTDAR 1387


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  552 bits (1422), Expect = e-157
 Identities = 392/966 (40%), Positives = 433/966 (44%), Gaps = 216/966 (22%)

Query: 246  GASGDSGSG--------------LGDARELLREETGAALKPRLPAPPPVTTPPLAGGSST 291
            G  GD+GS               L  AR  LR   G       P P     PP +GG   
Sbjct: 527  GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGP---VGPPGSGGLKG 583

Query: 292  EDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--------GLKGQKG 343
            E         +      G    PG    +  DG+   PG    +G        GL G+KG
Sbjct: 584  EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKG 643

Query: 344  EPGVPGPPGRAGPPGS---------------PCLPGPPGLPCPVSPLGPAGP----ALQT 384
              G PGP G  GPPG                P  PGP GL  P  P GP GP     +  
Sbjct: 644  HRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDG 703

Query: 385  VPGP------QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKG 438
             PGP      QG PGPPG+ G PG  G PG  G  G PG+ GP G PG PG  G  G  G
Sbjct: 704  QPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPG 763

Query: 439  DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----------GFGGDLE 481
             PG        G +GPPGPQGP G PGP           ++G+          GF GD+ 
Sbjct: 764  HPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM- 822

Query: 482  ALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP----------GPAGLPGVPGREGP- 530
             ++G RG  GPPGP G  G  G  GR G N    P          G  GLPG PGR+GP 
Sbjct: 823  GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK 882

Query: 531  -----PGFPGL---------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPA 576
                 PGFPG          PG PGP G+ GP G  G++G  G  G PG KG+ G  GPA
Sbjct: 883  GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPA 942

Query: 577  GARGESGLAGAPGPAGPPGPPGPPGPPG----PGLP-----AGFDDMEGSGGPFWSTA-- 625
            G  GE G  G  GP G PGP GPPGPPG    PG P      GF    G  GP       
Sbjct: 943  GPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQ 1002

Query: 626  -----------RSADGPQGPP---GLPGL------KGDPGVPGLPGAKGEVGADGVPGFP 665
                       R   GP GPP   GLPGL      KGDPG  GLPG  G  G  G PG  
Sbjct: 1003 GPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDR 1062

Query: 666  GLP------GREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQ 718
            GLP      G +G  GP GP G  GS GE+G  G  G +G PG PGP GPPGP     E+
Sbjct: 1063 GLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGP---AGEK 1119

Query: 719  DGSVLSVP-GPEGRPGF---AGFPGPAGP---------KGNLGSKGERGSPGPKGEKGEP 765
                   P GP GR G     G PGPAGP         KG +G  G++GS G KGE+G P
Sbjct: 1120 GAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPP 1179

Query: 766  GSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL---KGE 822
            G    P G    P   GA GEPG RG  G +G+ G +G  GFPG PG  G+ GL    GE
Sbjct: 1180 GPT-GPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238

Query: 823  KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP--------VYDSNVFAESSRP---GPPG 871
            KGE GD     G  G PGPPGP GP G PG          + +     E   P   G PG
Sbjct: 1239 KGETGDV----GQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG 1294

Query: 872  LPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGG 931
            LPG  GPPGPKG +GE G  GP G              G  G +G  G  G +G PG  G
Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSG------------AAGPPGPKGPPGDDGPKGSPGPVG 1342

Query: 932  FFGSSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGP---PGPQGPPG-------IGY 977
            F G   PGPPG PGP G  G PG KG+       G PGP   PGP GPPG        G 
Sbjct: 1343 FPGD--PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400

Query: 978  EGRQ------------GPP---GPPGPPGPPSFPGPHRQTISVPGP------PGPPGPPG 1016
            EGRQ            GPP   GP GP G P  PGP      +PGP      PG PGP G
Sbjct: 1401 EGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR-GIPGPVGEQGLPGSPGPDG 1459

Query: 1017 PPGTMG 1022
            PPG MG
Sbjct: 1460 PPGPMG 1465



 Score =  529 bits (1363), Expect = e-150
 Identities = 375/945 (39%), Positives = 425/945 (44%), Gaps = 164/945 (17%)

Query: 193  RGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD-GASGDS 251
            RGL  EPG    +   G   P    GV        D Q  P   +  +G+    G  G+ 
Sbjct: 672  RGLPGEPGPRGLLGPKGPPGPPGPPGVTG-----MDGQPGPKGNVGPQGEPGPPGQQGNP 726

Query: 252  GS-GLGDARELLRE--ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASL 308
            G+ GL   +  +    E G   KP LP  P    PP   G   ++    E   Q      
Sbjct: 727  GAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPP---GHPGKEGPPGEKGGQGPPGPQ 783

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPP 357
            G    PG   V   DG     G + ++G           G+KG +GE G PGP G  GP 
Sbjct: 784  GPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPE 843

Query: 358  GSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGED 413
            G     GP G P P+ P G  G    P L   PG QGP G  G  G PG +GE G  G  
Sbjct: 844  GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTP 903

Query: 414  GKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------------GERGPPGPQGPPG----- 455
            GKPG  G +G  G  G+ GP+G  G PG              GERGP GPQGP G     
Sbjct: 904  GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963

Query: 456  -PPGPSFRHDKLTFIDMEG-SGFGGDL-----------------EALRGPRGFPGPPGPP 496
             PPGP  +          G +GF G                       G RG PGPPGPP
Sbjct: 964  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023

Query: 497  GVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKG 556
            G  GLPG  G+ G      PGPAGLPG   ++GPPG  G PG  G PG   P G  G KG
Sbjct: 1024 GEQGLPGLAGKEGTKGD--PGPAGLPG---KDGPPGLRGFPGDRGLPG---PVGALGLKG 1075

Query: 557  SLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG---PGLPAGFDD 613
            + G  G PG  GS G  GPAGA G  G+ G PGP GPPGP G  G PG   P  PAG D 
Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135

Query: 614  MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------L 667
            ++G  G          GP GPPG  G KG+ G PG  G+KG+ G  G PG  G       
Sbjct: 1136 LQGPVG-----LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190

Query: 668  PGREGIAGPQGPKGDRGSRGEKGDPGKDG-------VGQPGLPGPPGPPGPVVYVSEQDG 720
            PG  G  G  GP+G +G  G+KGD G  G       VG  GLPGPPG  G    V +   
Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250

Query: 721  SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP-- 778
                 PGP G  G  G  GP GP G +G+ G  G  G  GE GEPG     +GG  GP  
Sbjct: 1251 P--GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG--LPGEGGPPGPKG 1306

Query: 779  --AQKGAKGEPGFRGPPGPYGRPG------YKGEIGFPGRPGRPGMNGLKGEKGEPGDAS 830
               +KG  G  G  GPPGP G PG        G +GFPG PG PG  G  G+ G PGD  
Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366

Query: 831  LGF--GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 888
                 G  G PGP G PGP GPPG             + GPPG  G +G  G KGAKGE 
Sbjct: 1367 DDGEPGQTGSPGPTGEPGPSGPPG-------------KRGPPGPAGPEGRQGEKGAKGEA 1413

Query: 889  GPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRG 948
            G  GPPG+      Q      G  G RG  G  GE+G PG         PGP GPPGP G
Sbjct: 1414 GLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS--------PGPDGPPGPMG 1465

Query: 949  YPGIPGPKGES-------------------------IRGQPGPPGPQGPPGI-GYEGRQG 982
             PG+PG KG+S                          RG PGP G  GP G  G  G  G
Sbjct: 1466 PPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG 1525

Query: 983  PPGPPGPPGPPSFPGPH--RQTISVPGP------PGPPGPPGPPG 1019
            P GPPGPPG P  PGP   + +    GP      PGPPGPPGPPG
Sbjct: 1526 PIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  512 bits (1319), Expect = e-145
 Identities = 327/744 (43%), Positives = 373/744 (50%), Gaps = 94/744 (12%)

Query: 307  SLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPG 364
            S+G    PG++      G+   PG R + G  G +G++G  G+ G PG  G  G     G
Sbjct: 884  SIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAG 943

Query: 365  PPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGF 424
            PPG   P  P GP G      PGP+GPPGPPG+DG PG    PG  GE G  G TGP   
Sbjct: 944  PPGERGPNGPQGPTG-----FPGPKGPPGPPGKDGLPGH---PGQRGETGFQGKTGP--- 992

Query: 425  PGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGD--- 479
            PG PG VGP+G  G+ G +GERG PGP GPPG  G P     + T  D   +G  G    
Sbjct: 993  PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGP 1052

Query: 480  --LEALRGPRGFPGP---------PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE 528
              L    G RG PGP          GPPG PG  G PG  G   +   GP G+PG PG +
Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERG--PAGAAGPIGIPGRPGPQ 1110

Query: 529  GPPG------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA---PGPAGAR 579
            GPPG       PG  GP GP GR+G  G  G  G  G  G PG  G KG    PG  G++
Sbjct: 1111 GPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSK 1170

Query: 580  GESGLAGAPGPAGPPGPPGPPGP------PGPGLPAGFDDMEGSGGPFWSTARSADGPQG 633
            G+ G  G PGP GP GP G PGP      PGP    G    +G  GP     R   GP G
Sbjct: 1171 GDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP-----RGFPGPPG 1225

Query: 634  PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG---DRGSRGEKG 690
            P GL GL G PG  G  G  G++G  G PG  G  G  G  GPQGP G   + G+ GEKG
Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG 1285

Query: 691  DPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750
            +PG+   G+PGLPG  GPPGP               G +G  G +G  GP GPKG  G  
Sbjct: 1286 EPGE--AGEPGLPGEGGPPGPK-----------GERGEKGESGPSGAAGPPGPKGPPGDD 1332

Query: 751  GERGSPGPKGEKGEPGSIFSPD--GGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP 808
            G +GSPGP G  G+PG    P   G    P  KG  GEPG  G PGP G PG  G  G  
Sbjct: 1333 GPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392

Query: 809  GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPG 868
            G PG  G  G +GEKG  G+A    G+ G PG  GP GP G PG P  D         PG
Sbjct: 1393 GPPGPAGPEGRQGEKGAKGEA----GLEGPPGKTGPIGPQGAPGKPGPDGL----RGIPG 1444

Query: 869  PPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 928
            P G  G  G PGP G  G +GPPG PG      L+ ++  KGEKG  G  G  G  GE G
Sbjct: 1445 PVGEQGLPGSPGPDGPPGPMGPPGLPG------LKGDSGPKGEKGHPGLIGLIGPPGEQG 1498

Query: 929  GGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGP- 986
              G  G  LPGP G  GP+G  GI GP G    G PGPPG  GPPG  G +G  GP GP 
Sbjct: 1499 EKGDRG--LPGPQGSSGPKGEQGITGPSGPI--GPPGPPGLPGPPGPKGAKGSSGPTGPK 1554

Query: 987  -----PGPPGPPSFPGPHRQTISV 1005
                 PGPPGPP  PG   Q + +
Sbjct: 1555 GEAGHPGPPGPPGPPGEVIQPLPI 1578



 Score =  495 bits (1275), Expect = e-139
 Identities = 413/1202 (34%), Positives = 498/1202 (41%), Gaps = 258/1202 (21%)

Query: 18   VLAPLVLLLGVRAASAEPERISEEVGLLQLLG-DPPPQQVTQTDD----------PDVGL 66
            +L PL+LLL     +  P R ++   LL++L     P  +T+T            PDV  
Sbjct: 19   LLPPLLLLL---LWAPPPSRAAQPADLLKVLDFHNLPDGITKTTGFCATRRSSKGPDV-- 73

Query: 67   AYVFGPDANSGQVARYHFP-SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 125
            AY    DA      +  +P S F  DFS+L  ++        L +I +        G++ 
Sbjct: 74   AYRVTKDAQLSAPTKQLYPASAFPEDFSILTTVKAKKGSQAFLVSIYNEQ------GIQQ 127

Query: 126  SGVQDGHQDISLLYTEPGAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCEEFQ 184
             G++ G   + L     G         FR +    G+W  +ALSV    V L +DC++  
Sbjct: 128  IGLELGRSPVFLYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNVTLILDCKKKT 187

Query: 185  RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDS 244
               L RS     +    G+ V      D + F+G I +L    D + +  +C +    D 
Sbjct: 188  TKFLDRSDH--PMIDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYC-EHYSPDC 244

Query: 245  DGASGDS--------------GSGLG-----------DARELLREETGA-----ALKPRL 274
            D A  D+              G G G           D  +L +E T +     A K   
Sbjct: 245  DTAVPDTPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETT 304

Query: 275  PAPPPVTTPPL---------AGGSSTED-------------------------SRSEEVE 300
              P  +T  P           G    ED                            EE  
Sbjct: 305  EVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENP 364

Query: 301  EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGE---------------- 344
            +Q T    GA+    +   S        PG    +  L+G+  E                
Sbjct: 365  DQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADD--LEGEFTEETIRNLDENYYDPYYD 422

Query: 345  ---------PGVPGP-----PGRAGPPGSPCLPGPPGLPCP----VSPLGPAGPA-LQTV 385
                     PG+P        G  GP G     G P +  P      P GP GPA L   
Sbjct: 423  PTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP 482

Query: 386  PGPQGPP---------GPPGRDGTPGRDGEPGDPG-------EDGKPGD----------- 418
            PG  GP          GPPGR G PG DG PG PG         G  GD           
Sbjct: 483  PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQ 542

Query: 419  ------------------TGPQGFPGTPGDVGPKGD---KGDPG-VGERGPPGPQGPPGP 456
                               GP G  G PG VGP G    KG+PG VG +GP G QGPPGP
Sbjct: 543  ESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGP 602

Query: 457  PGPSFRHDKLTFIDMEG----------SGFGG--DLEALRGPRGFPGPPGPPGVPGLPGE 504
             G   R  +       G           GF G   L   +G RG PGP GPPG PG  GE
Sbjct: 603  AGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGE 662

Query: 505  PGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAP 564
             G  G       GP GLPG PG  G  G  G PGPPGPPG  G  G+ G KG++G  G P
Sbjct: 663  RGDDG-----EVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEP 717

Query: 565  GHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWST 624
            G  G +G PG  G  G  G  G PG  GP G PG PG PG   P G    EG  G     
Sbjct: 718  GPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE--KG 775

Query: 625  ARSADGPQGPPGLP---GLKGDPGVPGLPGAKGEVGADGVPGFP---GLPGREGIAGPQG 678
             +   GPQGP G P   G+KG  G+ GL G KGE G DG PGF    G+ G  G  GP G
Sbjct: 776  GQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG 835

Query: 679  PKGDRGSRGEK------GDPG-------KDGVGQPGLPGPPGPPGPVVYVSEQDGSV--L 723
            P+G+ G  G K      GDPG       K  +G PGLPG PG  GP        GS+   
Sbjct: 836  PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP-------KGSIGFP 888

Query: 724  SVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGA 783
              PG  G  G  G PG  GP+G  G  G RG  GP+G  G+PG    P G + G    G 
Sbjct: 889  GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG----PKGNSGG---DGP 941

Query: 784  KGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPG 843
             G PG RGP GP G  G+ G  G PG PG+ G+ G  G++GE        G +G  GPPG
Sbjct: 942  AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET-------GFQGKTGPPG 994

Query: 844  PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQ 903
            PPG  GP G P  ++    E   PGPPG PG QG PG  G +G  G PGP G        
Sbjct: 995  PPGVVGPQG-PTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAG-------- 1045

Query: 904  LEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES-IR 961
                + G+ G  G  G  G+RG PG  G  G     GPPGPPGP G PG  GP G +   
Sbjct: 1046 ----LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPI 1101

Query: 962  GQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT 1020
            G PG PGPQGPPG  G +G  G  GP GP G     GP    + +PGP GP GPPG  G 
Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP----VGLPGPAGPVGPPGEDGD 1157

Query: 1021 MG 1022
             G
Sbjct: 1158 KG 1159



 Score =  447 bits (1151), Expect = e-125
 Identities = 284/636 (44%), Positives = 314/636 (49%), Gaps = 64/636 (10%)

Query: 263  REETGAALKPRLPAPPPVTTP---------------PLAGGSSTEDSRSEEVEEQTTVAS 307
            R ETG   K   P PP V  P               P   G   E        ++ T   
Sbjct: 981  RGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGD 1040

Query: 308  LGAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 365
             G   LPG D      G     G  G V   GLKG +G PG PGP G  G  G     GP
Sbjct: 1041 PGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGP 1100

Query: 366  PGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGF 424
             G+P    P GP GPA +   PG +GP GP GRDG  G  G PG  G  G PG+ G +G 
Sbjct: 1101 IGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGE 1160

Query: 425  PGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGDLEAL 483
             G PG  G KGDKG+ G    GP GPQGP G PGPS    +      +G  G  GD    
Sbjct: 1161 IGEPGQKGSKGDKGEQG--PPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD---- 1214

Query: 484  RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 543
             GPRGFPGPPGP G+ GLPG PG  G  + DV G  G PG PG  GP G PG  GP GPP
Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKG-ETGDV-GQMGPPGPPGPRGPSGAPGADGPQGPP 1272

Query: 544  GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 603
            G  G PG  G+KG  GEAG PG  G  G PGP G RGE G +G  G AGPPGP GPPG  
Sbjct: 1273 GGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDD 1332

Query: 604  GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 663
            GP    G     G  GP      +  G  GPPG  G  G+PG  G PG  GE G  G PG
Sbjct: 1333 GPKGSPGPVGFPGDPGPPGEPGPA--GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390

Query: 664  FPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSV 722
              G PG  G  G QG KG +G  G +G PGK G +G  G PG PGP G           +
Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG-----------L 1439

Query: 723  LSVPGPEGRPGFAGFPGPAGPKGNLGS---KGERGSPGPKGEKGEPGSIFSPDGGALGPA 779
              +PGP G  G  G PGP GP G +G     G +G  GPKGEKG PG I     G +GP 
Sbjct: 1440 RGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI-----GLIGP- 1493

Query: 780  QKGAKGEPGFRGPPGPYGRPGYKGE---------IGFPGRPGRPGMNGLKGEKGEPGDAS 830
              G +GE G RG PGP G  G KGE         IG PG PG PG  G KG KG  G   
Sbjct: 1494 -PGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPT- 1551

Query: 831  LGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 866
               G +G  G PGPPGPPGPPG  +    + A  +R
Sbjct: 1552 ---GPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTR 1584



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 57/209 (27%), Positives = 73/209 (34%), Gaps = 32/209 (15%)

Query: 845  PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQL 904
            P P   P     ++    E   P P      +  P P+ ++G  G     G   +D++  
Sbjct: 290  PTPSKKPVEAAKETTEVPEELTPTP-----TEAAPMPETSEG-AGKEEDVGIGDYDYVPS 343

Query: 905  EAEMKGEKGDRGDAGQKGERGE----PGGGGFFGSSLPGP-----PGPPGPRGYPGIPGP 955
            E        D    G+  E  +    PG G    +S         P PP   G   + G 
Sbjct: 344  EDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGE 403

Query: 956  -KGESIRG--------------QPGPPGPQGPPGIG--YEGRQGPPGPPGPPGPPSFPGP 998
               E+IR                P   GP  P      YEG  GP G  G  G P+   P
Sbjct: 404  FTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEP 463

Query: 999  HRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
                   PGP GP G PGPPGTMG +  V
Sbjct: 464  GMLIEGPPGPEGPAGLPGPPGTMGPTGQV 492


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  547 bits (1410), Expect = e-155
 Identities = 354/832 (42%), Positives = 392/832 (47%), Gaps = 129/832 (15%)

Query: 275  PAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVK 334
            P P      P   G + E  ++    E       G   +PG       DG   +PG    
Sbjct: 416  PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGA 475

Query: 335  EG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGP 391
             G  G  G++G PG  GP G  G PG     G  G P P  P G AG P    VPG  G 
Sbjct: 476  NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGM 535

Query: 392  PGPPGRDGTPGRDGEPGDPGEDGK------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GE 444
             G PG  G PG DG+PG PG  G+      PG +GP+G PG  G  GPKG+ G PG  GE
Sbjct: 536  RGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE 595

Query: 445  RGPPG---PQGPPG---------PPGPSFRHDKLTFIDMEGSGFGGDL-----EALRGPR 487
            RG PG   PQGPPG         PPGP+              G GGD         +G +
Sbjct: 596  RGGPGGPGPQGPPGKNGETGPQGPPGPT--------------GPGGDKGDTGPPGPQGLQ 641

Query: 488  GFPGPPGPPGVPGLPGEPGRFG-VNSSDVPGPAGLPGVPGREGPPGFPGLPG-------- 538
            G PG  GPPG  G PGEPG  G   +   PG  G  G PG  GPPG  G PG        
Sbjct: 642  GLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP 701

Query: 539  ----------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAP 588
                      PPGPPG  G PG  G  G  G  G+PG KG KG PG  GA G  G  G  
Sbjct: 702  GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPR 761

Query: 589  GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTA-RSADGPQGP---PGLPGLKGDP 644
            GP GP GPPGP G PG     G   + G  GP  S   R   GP GP   PG PG  G+P
Sbjct: 762  GPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEP 821

Query: 645  GVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLP 703
            G  G  GA GE G  G PG  G PG  G AGP GP+G +G RG  G PG  G  G  GLP
Sbjct: 822  GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP 881

Query: 704  GPPG------PPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPG 757
            GPPG      PPGP     + DG     PGP G  G  G PG +GPKG+ G  GE+GSPG
Sbjct: 882  GPPGSNGNPGPPGPSGSPGK-DGP----PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG 936

Query: 758  PKGEKGEPG-----------SIFSPDG-----GALGP-------AQKGAKGEPGFRGPPG 794
             +G  G PG            +  P G     G+ GP        + GA G  G RGPPG
Sbjct: 937  AQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG 996

Query: 795  PYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP 854
            P G PG  G  G PGR G PG +GL G  G PG      G  G PG PG PG PGPPG P
Sbjct: 997  PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKG-DRGENGSPGAPGAPGHPGPPG-P 1054

Query: 855  VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914
            V  +    +    GP G     G PGP G++G  GP GP G             KGE G+
Sbjct: 1055 VGPAGKSGDRGESGPAG---PAGAPGPAGSRGAPGPQGPRGD------------KGETGE 1099

Query: 915  RGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG 974
            RG AG KG RG PG  G      PG PGP G +G  G PGP G       GP GP GPPG
Sbjct: 1100 RGAAGIKGHRGFPGNPG-----APGSPGPAGQQGAIGSPGPAGPR-----GPVGPSGPPG 1149

Query: 975  IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1026
               +G  G PGP GPPGP    G  R +   PG PG PGPPGPPG  G   G
Sbjct: 1150 --KDGTSGHPGPIGPPGPRGNRG-ERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198



 Score =  528 bits (1359), Expect = e-149
 Identities = 350/882 (39%), Positives = 396/882 (44%), Gaps = 152/882 (17%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G SG +G      R     E G    P +  P  +   P   G    D R+ E  E    
Sbjct: 222  GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAP 281

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRA 354
               G   LPG +      G    PG R + G           G +G  G+PG PGPPG A
Sbjct: 282  GLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTA 341

Query: 355  GPPGSPCL---------------------------------PGPPGL---PCPVSPLGPA 378
            G PGSP                                   PGPPG+   P     +GPA
Sbjct: 342  GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401

Query: 379  G-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQG------FPGTPGDV 431
            G P    + G +GPPGP G +G PG  G  G+PG++G  G+ GP+G       PG PG  
Sbjct: 402  GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461

Query: 432  GPKGDKGDPG----------VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLE 481
            G  G  G PG           GERG PG +GP GP G                     + 
Sbjct: 462  GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG---------------------IP 500

Query: 482  ALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPG 541
              +GP G  G PGP G  G  GEPGR GV     PG  G+PG PG  G  G PG PG  G
Sbjct: 501  GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG--PGMRGMPGSPGGPGSDGKPGPPGSQG 558

Query: 542  PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG 601
              GR GPPG +G +G  G  G PG KG+ GAPG  G RG  G  G  GP G  G  GP G
Sbjct: 559  ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQG 618

Query: 602  PPGPGLPA------------GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGL 649
            PPGP  P             G   + G+GGP         G  G PG PG KGD G PG 
Sbjct: 619  PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGP--------PGENGKPGEPGPKGDAGAPGA 670

Query: 650  PGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 708
            PG KG+ GA G  G PGL G  G+ G  GP G  G +G  G PG  G  G PGL G PG 
Sbjct: 671  PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE 730

Query: 709  PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768
             G +     +       PG  G  G  G  GP GP G +G  G  G PG KGE G PG  
Sbjct: 731  RGGLGSPGPKGDK--GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL- 787

Query: 769  FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828
                 G  GP  +G+ GE G  GPPGP G PG  G+ G PG  G  G  G KGE G PG 
Sbjct: 788  ----PGIAGP--RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841

Query: 829  ASL--GFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG 886
            A    G G  G PGP G  G  G PG P   +        PGPPG  GN GPPGP G+ G
Sbjct: 842  AGPPGGSGPAGPPGPQGVKGERGSPGGP-GAAGFPGARGLPGPPGSNGNPGPPGPSGSPG 900

Query: 887  EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS----------- 935
            + GPPGP G              G  G +GDAGQ GE+G PG  G  G+           
Sbjct: 901  KDGPPGPAGNTG------APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITG 954

Query: 936  --SLPGPPGPPGPRGYPGIPGPKGES-------IRGQPGPPGPQGPPGI----GYEGRQG 982
               L GPPG PGPRG PG  G KGES       + G+ GPPGPQG PG+    G  GR G
Sbjct: 955  ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014

Query: 983  PPGPPGPPGPPSFPG--PHRQTISVPGPPGPPGPPGPPGTMG 1022
             PG  G PG    PG    R     PG PG PG PGPPG +G
Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056



 Score =  527 bits (1358), Expect = e-149
 Identities = 336/797 (42%), Positives = 376/797 (47%), Gaps = 133/797 (16%)

Query: 327  RTPGGRVKEGGLKGQKGEPGVPG---PPGRAGPPGSPCLPGPPGL--PCPVSPL------ 375
            R P G+  +G  KG  G PG+PG    PG  G PGSP  PGPPG+   CP  P       
Sbjct: 97   RPPNGQGPQGP-KGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQY 155

Query: 376  -------GPAGPALQTVPGPQGPP---GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP 425
                   G A   L   PGP GPP   GPPG  G PG  G PG  G  G+PG  GP G P
Sbjct: 156  DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPP 215

Query: 426  GTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEG-SGFGG----- 478
            G PG +GP G  G  G  G  G PG +G PGPPG         F  M+G  GF G     
Sbjct: 216  GPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEK 275

Query: 479  ---------DLEALRGPRGFPGPPGPPGVP---GLPGEPGRFGVNSSD-VPGPAGLPGVP 525
                         L G  G PGP GP G P   G PG PG  G   +D   G  G PG P
Sbjct: 276  GETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP 335

Query: 526  GREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLA 585
            G  G  GFPG PG  G  G  G PG  G  G  GE G  GH G++G PGP G  G  G  
Sbjct: 336  GPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGK 395

Query: 586  GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPG 645
            G  GPAG PG PG  G  GP  PAG +   G  G      +  +G +G PG  G +G+ G
Sbjct: 396  GEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK--NGAKGEPGPRGERGEAG 453

Query: 646  VPGLPGAKGEVGADGVPGFP------------------------GLPGREGIAGPQGPKG 681
            +PG+PGAKGE G DG PG P                        G+PG +G AG +G  G
Sbjct: 454  IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG 513

Query: 682  DRGSRGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF 737
              G RG  G+PG+DGV    G  G+PG PG PG        DG     PGP G  G +G 
Sbjct: 514  PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG-------SDGK----PGPPGSQGESGR 562

Query: 738  PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYG 797
            PGP GP G  G  G  G PGPKG  G PG      GG  GP  +G  G+ G  GP GP G
Sbjct: 563  PGPPGPSGPRGQPGVMGFPGPKGNDGAPGK-NGERGGPGGPGPQGPPGKNGETGPQGPPG 621

Query: 798  RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857
              G  G+ G  G PG  G+ GL G  G PG+        G PG PGP G  G PG P   
Sbjct: 622  PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE-------NGKPGEPGPKGDAGAPGAPGGK 674

Query: 858  SNVFAESSR-----PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912
             +  A   R      G PGL G  GPPGP+G KG  GPPGPPG      LQ    M GE+
Sbjct: 675  GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ---GMPGER 731

Query: 913  GDRGDAGQKGERGEPGGGGFFG-------SSLPGPPGPPGPR------------GYPGIP 953
            G  G  G KG++GEPGG G  G           GP GPPGP             G PGI 
Sbjct: 732  GGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791

Query: 954  GPKGE-SIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1005
            GP+G    RG+ GPPGP G PG        G +G +G PG  G  GPP   GP       
Sbjct: 792  GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP------- 844

Query: 1006 PGPPGPPGPPGPPGTMG 1022
            PG  GP GPPGP G  G
Sbjct: 845  PGGSGPAGPPGPQGVKG 861



 Score =  469 bits (1206), Expect = e-131
 Identities = 312/728 (42%), Positives = 335/728 (46%), Gaps = 137/728 (18%)

Query: 370  CPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPG 429
            CP  P  P  P      GPQGP G PG  G PGR+G+PG PG+            PG+PG
Sbjct: 88   CPQPPTAPTRPP--NGQGPQGPKGDPGPPGIPGRNGDPGIPGQ------------PGSPG 133

Query: 430  DVGPKG----------------DKGD--PGV---GERGPPGPQGPPGPPGPSFRHDKLTF 468
              GP G                D  D   GV   G  G PGP GPPGPPGP         
Sbjct: 134  SPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPP-------- 185

Query: 469  IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGL 521
                            G  G PG PG PG  G PGEPG+ G +    P       GPAG 
Sbjct: 186  ----------------GTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGK 229

Query: 522  PGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGE 581
             G  GR G PG  GLPGPPG  G  G PG  G KG  G  G  G KG  GAPG  G  G 
Sbjct: 230  DGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGL 289

Query: 582  SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLK 641
             G  GAPGP GP G PG  G PG    AG    +G        AR +DG  GPPG P   
Sbjct: 290  PGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG--------ARGSDGQPGPPGPP--- 338

Query: 642  GDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ---------GPKGDRGSRGEKGDP 692
            G  G PG PGAKGEVG  G PG  G PG+ G  GPQ         GP G  GS G KG+ 
Sbjct: 339  GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEM 398

Query: 693  GKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKG 751
            G  G+ G PGL G  GPPGP             + G  G PG  G  G  GP+G  G  G
Sbjct: 399  GPAGIPGAPGLMGARGPPGPA-----GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAG 453

Query: 752  ERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRP 811
              G PG KGE G+ GS   P    L P   G +G PGFRGP GP G PG KG  G  G P
Sbjct: 454  IPGVPGAKGEDGKDGSPGEPGANGL-PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAP 512

Query: 812  GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPP- 870
            G  G  G  GE G  G    G GMRGMPG PG PG  G PG P        ES RPGPP 
Sbjct: 513  GPAGPRGAAGEPGRDGVPG-GPGMRGMPGSPGGPGSDGKPGPP----GSQGESGRPGPPG 567

Query: 871  -----GLPGNQGPPGPK------GAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAG 919
                 G PG  G PGPK      G  GE G PG PG         E   +G  G  G  G
Sbjct: 568  PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG 627

Query: 920  QKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES-------IRGQPGPPGPQGP 972
             KG+ G PG  G  G  LPG  GPPG  G PG PGPKG++        +G  G PG +GP
Sbjct: 628  DKGDTGPPGPQGLQG--LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGP 685

Query: 973  PGI----GYEGRQGPPGP------PGPPGPPSFPGP--------HRQTISVPGPPGPPGP 1014
            PG+    G  G  GPPGP       GPPGPP   G          R  +  PGP G  G 
Sbjct: 686  PGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745

Query: 1015 PGPPGTMG 1022
            PG PG  G
Sbjct: 746  PGGPGADG 753



 Score =  238 bits (606), Expect = 4e-62
 Identities = 154/369 (41%), Positives = 171/369 (46%), Gaps = 68/369 (18%)

Query: 675  GPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPG--------PVVYVSEQDGSVLSV 725
            GPQGPKGD G  G  G  G  G+ GQPG PG PGPPG        P  Y  + D     V
Sbjct: 103  GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS--YDV 160

Query: 726  PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG 785
                   G AG+PGPAGP G          PGP G  G PGS                 G
Sbjct: 161  KSGVAVGGLAGYPGPAGPPG---------PPGPPGTSGHPGS----------------PG 195

Query: 786  EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP 845
             PG++GPPG  G+ G  G  G PG  G  G  G  GE G PG      G RG+PGPPG  
Sbjct: 196  SPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP----GERGLPGPPGIK 251

Query: 846  GPPGPPGTPVYDSNVF-----AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900
            GP G PG P    +        E    G PGL G  G PG  GA G +GP G PG+    
Sbjct: 252  GPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGE---- 307

Query: 901  FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-- 958
                    +G  G  G AG +G  G  G  G      PGPPGPPG  G+PG PG KGE  
Sbjct: 308  --------RGRPGLPGAAGARGNDGARGSDG-----QPGPPGPPGTAGFPGSPGAKGEVG 354

Query: 959  --SIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPP 1015
                 G  G PG +G PG  G+ G QGPPGPPG  G P   G       +PG PG  G  
Sbjct: 355  PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG-EMGPAGIPGAPGLMGAR 413

Query: 1016 GPPGTMGAS 1024
            GPPG  GA+
Sbjct: 414  GPPGPAGAN 422



 Score =  209 bits (531), Expect = 2e-53
 Identities = 147/362 (40%), Positives = 161/362 (44%), Gaps = 73/362 (20%)

Query: 676  PQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFA 735
            P  P   +G +G KGDPG      PG+PG  G                  PG  G+PG  
Sbjct: 95   PTRPPNGQGPQGPKGDPGP-----PGIPGRNGD-----------------PGIPGQPGSP 132

Query: 736  GFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGP 795
            G PGP G         E    GP+    +  S     G A+G    G  G PG  GPPGP
Sbjct: 133  GSPGPPGIC-------ESCPTGPQNYSPQYDSYDVKSGVAVG----GLAGYPGPAGPPGP 181

Query: 796  YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV 855
             G PG  G       PG PG  G +G  GEPG A    G  G PGPPG  GP GP G   
Sbjct: 182  PGPPGTSGH------PGSPGSPGYQGPPGEPGQA----GPSGPPGPPGAIGPSGPAGKD- 230

Query: 856  YDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 915
                   ES RPG PG  G  GPPG KG  G  G PG  G   FD         GEKG+ 
Sbjct: 231  ------GESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD------GRNGEKGET 278

Query: 916  GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG----ESIRGQPGPPGPQG 971
            G  G KGE G PG  G  G    GP G PG RG PG+PG  G    +  RG  G PGP G
Sbjct: 279  GAPGLKGENGLPGENGAPGPM--GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG 336

Query: 972  PPGI----GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG---PPGPPGPPGTMGAS 1024
            PPG     G  G +G  GP G PG    PG   +    PGP G     GPPGPPG  G+ 
Sbjct: 337  PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE----PGPQGHAGAQGPPGPPGINGSP 392

Query: 1025 SG 1026
             G
Sbjct: 393  GG 394



 Score =  187 bits (476), Expect = 4e-47
 Identities = 125/310 (40%), Positives = 142/310 (45%), Gaps = 61/310 (19%)

Query: 752  ERGSPGPKGEKGE-----PGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIG 806
            E   P P+   GE     P    +P     G   +G KG+PG  G PG  G PG  G+ G
Sbjct: 71   ELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG 130

Query: 807  FPGRPGRPGM-----NGLKG--EKGEPGDASLGF---GMRGMPGPPGPPGPPGPPGTPVY 856
             PG PG PG+      G +    + +  D   G    G+ G PGP GPPGPPGPPGT   
Sbjct: 131  SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT--- 187

Query: 857  DSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRG 916
                   S  PG PG PG QGPPG  G  G  GPPGPPG                 G  G
Sbjct: 188  -------SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI---------------GPSG 225

Query: 917  DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-------SIRGQPGPPGP 969
             AG+ GE G PG  G  G  LPGPPG  GP G PG PG KG          +G+ G PG 
Sbjct: 226  PAGKDGESGRPGRPGERG--LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGL 283

Query: 970  QGPPGI----GYEGRQGPPGPPGPPGPPSFPGPH--------RQTISVPGPPGPPGPPGP 1017
            +G  G+    G  G  GP G PG  G P  PG          R +   PGPPGPPG  G 
Sbjct: 284  KGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGF 343

Query: 1018 PGTMGASSGV 1027
            PG+ GA   V
Sbjct: 344  PGSPGAKGEV 353


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  545 bits (1405), Expect = e-155
 Identities = 366/891 (41%), Positives = 413/891 (46%), Gaps = 163/891 (18%)

Query: 238  DEEGDDSDGASGDSG--SGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSR 295
            D+E    +G  GD+G     G A    R+  G   +P LP PP    PP   G       
Sbjct: 104  DQETTGVEGPKGDTGPRGPRGPAGPPGRD--GIPGQPGLPGPPGPPGPPGPPGLG----- 156

Query: 296  SEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAG 355
                       +   Q   G D  ST   SV  P G     G +G  G PG PGP G  G
Sbjct: 157  ----------GNFAPQLSYGYDEKSTGGISVPGPMG---PSGPRGLPGPPGAPGPQGFQG 203

Query: 356  PPGSPCLPGPPGLPCPVSPLGPAGPALQTV----------PGPQGPPGPPGRDGTPGR-- 403
            PPG P   G PG   P+ P GP GP  +            PG +GPPGP G  G PG   
Sbjct: 204  PPGEP---GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260

Query: 404  -------------------------DGEPGDPGEDGKPGDTGPQGFPGT---PGDVGPKG 435
                                      GEPG PGE+G PG  GP+G PG    PG  GP G
Sbjct: 261  LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAG 320

Query: 436  DKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPG 494
             +G+ G  G  GPPGP GP GPPG  F        +    G  G  E  +G RG PGPPG
Sbjct: 321  ARGNDGATGAAGPPGPTGPAGPPG--FPGAVGAKGEAGPQGPRGS-EGPQGVRGEPGPPG 377

Query: 495  PPGV------PGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGP 548
            P G       PG  G+PG  G N +  PG AG PG PG  GP G  G  GPPGP G  G 
Sbjct: 378  PAGAAGPAGNPGADGQPGAKGANGA--PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435

Query: 549  PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLP 608
            PG  G KG  G  G PG  G +G PGPAG  G+ G  G PGP G PGPPG  G PG    
Sbjct: 436  PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495

Query: 609  AGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP------ 662
             G D + G  GP  +  R + GP GP G PG  G PG  GLPGAKG  G+ G P      
Sbjct: 496  PGADGVAGPKGP--AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT 553

Query: 663  GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-------VGQPGLPGPP--------- 706
            G PG  G++G  GP GP G RG  G  G PG  G        G+ G+PGPP         
Sbjct: 554  GPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD 613

Query: 707  ------GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGER------G 754
                  GPPGP     E+        GP G PGF G PGPAGP G  G  GE+      G
Sbjct: 614  GEAGAQGPPGPAGPAGER-----GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLG 668

Query: 755  SPGPKGEKGEPG-----SIFSPDG-----GALG-PAQKGAKGEPGFRGPPGPYGRPGYKG 803
            +PGP G +GE G      +  P G     GA G P   GAKG+ G  G PG  G PG +G
Sbjct: 669  APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG 728

Query: 804  EIGFPGRPGRPGMNGLKGEKGEPG-DASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861
              G  G  G PG  G +G+ G  G D S G  G+RG+ GP GPPGP G PG    +S   
Sbjct: 729  MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK-GESGPS 787

Query: 862  AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921
              +   G  G PG++G PGP G  G  GPPG  GQ             G KG+ GDAG K
Sbjct: 788  GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ------------PGAKGEPGDAGAK 835

Query: 922  GERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI------ 975
            G+ G PG          GP GPPGP G  G PG KG   RG  GPPG  G PG       
Sbjct: 836  GDAGPPGPA--------GPAGPPGPIGNVGAPGAKG--ARGSAGPPGATGFPGAAGRVGP 885

Query: 976  -GYEGRQGPPGPPGPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGA 1023
             G  G  GPPGPPGP G     GP  +T     PG  GPPGPPGP G  G+
Sbjct: 886  PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGS 936



 Score =  533 bits (1372), Expect = e-151
 Identities = 370/933 (39%), Positives = 420/933 (45%), Gaps = 157/933 (16%)

Query: 187  PLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQ-----VSPMHCLDEEG 241
            P    +RG +   GA       G A P  F G +   K    PQ       P     E G
Sbjct: 316  PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA-KGEAGPQGPRGSEGPQGVRGEPG 374

Query: 242  DDSD-GASGDSGSGLGDARELLREETGA---ALKPRLPAPPPVTTPPLAGGSSTEDSRSE 297
                 GA+G +G+   D +   +   GA   A  P  P     + P   GG       S 
Sbjct: 375  PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434

Query: 298  EVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPP 357
            E     +    GA+  PG   V    G    P G   + G +G+ G  G+PGPPG  G P
Sbjct: 435  EPGAPGSKGDTGAKGEPGPVGVQGPPG----PAGEEGKRGARGEPGPTGLPGPPGERGGP 490

Query: 358  GSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGR---------DGEPG 408
            GS   PG  G+  P  P G  G      PGP GP G PG  G PG           G PG
Sbjct: 491  GSRGFPGADGVAGPKGPAGERGS-----PGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPG 545

Query: 409  DPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----------------GERGPPGP-- 450
             PG DGK G  GP G  G PG  GP G +G  GV                GERG PGP  
Sbjct: 546  SPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPG 605

Query: 451  -------------QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 497
                         QGPPGP GP+    +         G  G      G +G PGP GPPG
Sbjct: 606  AVGPAGKDGEAGAQGPPGPAGPAGERGE--------QGPAGS----PGFQGLPGPAGPPG 653

Query: 498  VPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG---LPGPPGPPGREGPPGRTGQ 554
              G PGE G        VPG  G PG  G  G  GFPG   + GPPGP G  G  G  G 
Sbjct: 654  EAGKPGEQG--------VPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705

Query: 555  KGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDM 614
             G+ G+AGAPG  GS+GAPG  G  GE G AG PGP G  G  GP G  G     G D +
Sbjct: 706  DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS---PGKDGV 762

Query: 615  EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 674
             G  GP         GP GP G PG KG+ G  G  G  G  GA G  G PG PG  G A
Sbjct: 763  RGLTGPI--------GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFA 814

Query: 675  GPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGS----VLSVPGPE 729
            GP G  G  G++GE GD G  G  G PG  GP GPPGP+  V              PG  
Sbjct: 815  GPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGAT 874

Query: 730  GRPGFAGFPGPAGPKGNLGSKG------ERGSPGPKGEKG---EPGSIFSPDGGALGPAQ 780
            G PG AG  GP GP GN G  G      + G  GP+GE G    PG +  P  G  GPA 
Sbjct: 875  GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPP--GPPGPA- 931

Query: 781  KGAKGEPGFRGP------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDA--SLG 832
             G KG PG  GP      PGP G  G +G +G PG+ G  G  GL G  GEPG    S  
Sbjct: 932  -GEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990

Query: 833  FGMRGMPGPPGPPGPPGPPG------------TPVYDSNVFAESSR-----------PGP 869
             G RG PGP GPPG  GPPG            +P  D +  A+  R           PG 
Sbjct: 991  SGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050

Query: 870  PGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGG 929
            PG PG  GP G  G +GE GP GP G       +  A  +G +GD+G+ G++G+RG  G 
Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGH 1110

Query: 930  GGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI----GYEGRQGPPG 985
             GF G  L GPPGPPG    PG  GP G S     GP GP+GPPG     G +G  G PG
Sbjct: 1111 RGFSG--LQGPPGPPGS---PGEQGPSGAS-----GPAGPRGPPGSAGAPGKDGLNGLPG 1160

Query: 986  PPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPP 1018
            P GPPGP    G     +  PGPPGPPGPPGPP
Sbjct: 1161 PIGPPGPRGRTGD-AGPVGPPGPPGPPGPPGPP 1192



 Score =  528 bits (1361), Expect = e-149
 Identities = 352/818 (43%), Positives = 394/818 (48%), Gaps = 170/818 (20%)

Query: 337  GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-------ALQ------ 383
            G++G KG+ G  GP G AGPPG   +PG PGLP P  P GP GP       A Q      
Sbjct: 109  GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168

Query: 384  -------TVPGPQGP------PGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD 430
                   +VPGP GP      PGPPG  G  G  G PG+PGE G  G  GP+G PG PG 
Sbjct: 169  EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228

Query: 431  VGPKGDKGDPG-VGERGPPGPQGPPGPPG----PSFR-HDKLTFIDMEGSGFGGDLEALR 484
             G  G+ G PG  GERGPPGPQG  G PG    P  + H   + +D    G  GD     
Sbjct: 229  NGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD----GAKGDAGPA- 283

Query: 485  GPRGFPGPPGPPGVPG------LPGEPGRFGV-------NSSDVPGPAGLPGVPGREGPP 531
            GP+G PG PG  G PG      LPGE GR G         +    G AG PG  G  GPP
Sbjct: 284  GPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP 343

Query: 532  GFPGL------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA---PGPAGARGES 582
            GFPG        GP GP G EGP G  G+ G  G AGA G  G+ GA   PG  GA G  
Sbjct: 344  GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403

Query: 583  GLAGAPG------PAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSADGPQ 632
            G+AGAPG      P+GP GP GPPGP G    PG P    D    G P     +   GP 
Sbjct: 404  GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463

Query: 633  GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGS---RGEK 689
            G  G  G +G+PG  GLPG  GE G    PG  G PG +G+AGP+GP G+RGS    G K
Sbjct: 464  GEEGKRGARGEPGPTGLPGPPGERGG---PGSRGFPGADGVAGPKGPAGERGSPGPAGPK 520

Query: 690  GDPGKDG-------------VGQPGLPGPPG---PPGPVVYVSEQDG--SVLSVPGPEGR 731
            G PG+ G              G PG PGP G   PPGP    + QDG       PG  G+
Sbjct: 521  GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP----AGQDGRPGPPGPPGARGQ 576

Query: 732  PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP----------AQK 781
             G  GFPGP G  G  G  GERG PGP G  G  G     + GA GP           ++
Sbjct: 577  AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK--DGEAGAQGPPGPAGPAGERGEQ 634

Query: 782  GAKGEPGFRGPPGPYGRPGYKG---EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 838
            G  G PGF+G PGP G PG  G   E G PG  G PG +G +GE+G PG+       RG+
Sbjct: 635  GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE-------RGV 687

Query: 839  PGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFP 898
             GPPGP GP G  G P  D          G PG PG+QG PG +G  GE G  G PG   
Sbjct: 688  QGPPGPAGPRGANGAPGNDG----AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP-- 741

Query: 899  FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 958
                         KGDRGDAG KG  G PG  G  G  L GP GPPGP G PG  G  G 
Sbjct: 742  -------------KGDRGDAGPKGADGSPGKDGVRG--LTGPIGPPGPAGAPGDKGESGP 786

Query: 959  S-------------IRGQPGPPGPQG---PPGI----------GYEGRQGPPGPPGPPGP 992
            S              RG+PGPPGP G   PPG           G  G +G  GPPGP GP
Sbjct: 787  SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846

Query: 993  PSFPGPHRQTISVPGPPGP---PGPPGPPGTMGASSGV 1027
               PGP    +  PG  G     GPPG  G  GA+  V
Sbjct: 847  AGPPGPIGN-VGAPGAKGARGSAGPPGATGFPGAAGRV 883



 Score =  527 bits (1357), Expect = e-149
 Identities = 347/839 (41%), Positives = 386/839 (46%), Gaps = 111/839 (13%)

Query: 245  DGASGDSGSGLGDARELLREETGAA--LKPR-LPAPPPVTTPPLAGGSSTEDSRSEEVEE 301
            DGA GD+G            E GA   + PR LP        P   G+   D  +     
Sbjct: 274  DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP 333

Query: 302  QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPC 361
                   G    PG+       G     G R  EG  +G +GEPG PGP G AGP G+P 
Sbjct: 334  PGPTGPAGPPGFPGAVGAK---GEAGPQGPRGSEGP-QGVRGEPGPPGPAGAAGPAGNPG 389

Query: 362  LPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP 421
              G PG        G AG      PG +GP GP G  G PG  G  G+PG  G  GDTG 
Sbjct: 390  ADGQPGAKGANGAPGIAGAP--GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447

Query: 422  QGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480
            +G PG  G  GP G  G+ G  G RG PGP G PGPPG         F   +G      +
Sbjct: 448  KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG------V 501

Query: 481  EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540
               +GP G  G PGP G  G PGE GR G   + +PG  GL G PG  GP G  G PGP 
Sbjct: 502  AGPKGPAGERGSPGPAGPKGSPGEAGRPG--EAGLPGAKGLTGSPGSPGPDGKTGPPGPA 559

Query: 541  GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP 600
            G  GR GPPG  G +G  G  G PG KG+ G PG AG RG  G  GA GPAG  G  G  
Sbjct: 560  GQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ 619

Query: 601  GPPGPGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 659
            GPPGP  PAG     G  GP  S   +   GP GPPG  G  G+ GVPG  GA G  GA 
Sbjct: 620  GPPGPAGPAG---ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676

Query: 660  GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQ 718
            G  GFPG     G+ GP GP G RG+ G  G+ G  G  G PG PG  G PG        
Sbjct: 677  GERGFPG---ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG-------- 725

Query: 719  DGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP 778
                  + G  G  G AG PGP G +G+ G KG  GSPG  G +G  G I  P G A  P
Sbjct: 726  ------LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI-GPPGPAGAP 778

Query: 779  AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPG---RPGMNGLKGEKGEPGDASLGFGM 835
              KG  G  G  GP G  G PG +GE G PG  G    PG +G  G KGEPGDA    G 
Sbjct: 779  GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA----GA 834

Query: 836  RGMPGPPGPPGPPGPPGT-----------------PVYDSNVFAESSRPGPPGLPGNQGP 878
            +G  GPPGP GP GPPG                  P   +     + R GPPG  GN GP
Sbjct: 835  KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP 894

Query: 879  PGPKGAKG------------------EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 920
            PGP G  G                  EVGPPGPPG              GEKG  G  G 
Sbjct: 895  PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP------------AGEKGSPGADGP 942

Query: 921  KGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE-------SIRGQPGPPGPQGP 972
             G  G PG  G  G   + G PG  G RG+PG+PGP GE          G+ GPPGP GP
Sbjct: 943  AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP 1002

Query: 973  PGI----GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
            PG+    G  GR+G PG  G PG    PG         G  GP GPPG PG  GA   V
Sbjct: 1003 PGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR----GETGPAGPPGAPGAPGAPGPV 1057



 Score =  495 bits (1274), Expect = e-139
 Identities = 335/844 (39%), Positives = 374/844 (44%), Gaps = 187/844 (22%)

Query: 351  PGRAGPPGSPCLPGPPGLPCPVSP--LGPAGPALQTVP-GPQGPPGPPGRDGTPGRDGEP 407
            PG   P G  C   P G   P      G  GP   T P GP+GP GPPGRDG PG+ G P
Sbjct: 82   PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 408  GDPGEDGKPGDTGPQGFPGTP---GDVGPK-----GDKGDPGVGERGPPGPQGPPGPPGP 459
            G PG         P G PG P   G+  P+      +K   G+   GP GP GP G PGP
Sbjct: 142  GPPG---------PPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGP 192

Query: 460  SFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------VNS 512
                    F    G           GPRG PGPPG  G  G  G+PGR G         +
Sbjct: 193  PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGA 252

Query: 513  SDVPGPAGLPGVPGREGPPGFPGL---PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 569
              +PG AGLPG+ G  G  G  G     GP GP G  G PG  G  G +G  G PG +G 
Sbjct: 253  RGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGR 312

Query: 570  KGAPGPAGARGE---SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626
             GAPGPAGARG    +G AG PGP GP GPPG PG  G    AG     GS GP     R
Sbjct: 313  PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP--QGVR 370

Query: 627  SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSR 686
               GP GP G  G  G+PG  G PGAKG  GA G+ G PG PG  G +GPQGP G  G +
Sbjct: 371  GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPK 430

Query: 687  GEKGDPGKDG-------VGQPGLPGPPGPPGPVVYVSEQ----DGSVLSVPGPEGR---P 732
            G  G+PG  G        G+PG  G  GPPGP     ++    +     +PGP G    P
Sbjct: 431  GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP 490

Query: 733  GFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP 792
            G  GFPG  G  G  G  GERGSPGP G KG PG    P    L P  KG  G PG  GP
Sbjct: 491  GSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL-PGAKGLTGSPGSPGP 549

Query: 793  PGPYGRPGYKGEIGFPGRPGRPGMNGL---------KGEKGEPGDASLGFGMRGMPGPP- 842
             G  G PG  G+ G PG PG PG  G          KG  GEPG A    G RG+PGPP 
Sbjct: 550  DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA----GERGVPGPPG 605

Query: 843  --------------GPPGP---------PGPPGTPVYD-----SNVFAESSRPGPPGLPG 874
                          GPPGP          GP G+P +      +    E+ +PG  G+PG
Sbjct: 606  AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665

Query: 875  NQGPPGPKGAKGE---------VGPPGP------------------------------PG 895
            + G PGP GA+GE          GPPGP                              PG
Sbjct: 666  DLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG 725

Query: 896  QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGP 955
                   +  A + G KGDRGDAG KG  G PG  G  G  L GP GPPGP G PG  G 
Sbjct: 726  LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG--LTGPIGPPGPAGAPGDKGE 783

Query: 956  KGES-------------IRGQPGPPGP---QGPPG-------------IGYEGRQGPPGP 986
             G S              RG+PGPPGP    GPPG              G +G  GPPGP
Sbjct: 784  SGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP 843

Query: 987  PGPPGPP------------------------SFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
             GP GPP                         FPG   + +  PGP G  GPPGPPG  G
Sbjct: 844  AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR-VGPPGPSGNAGPPGPPGPAG 902

Query: 1023 ASSG 1026
               G
Sbjct: 903  KEGG 906



 Score =  408 bits (1048), Expect = e-113
 Identities = 271/667 (40%), Positives = 304/667 (45%), Gaps = 97/667 (14%)

Query: 267  GAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSV 326
            GAA +P       V  PP A G + +D  +            GAQ  PG           
Sbjct: 587  GAAGEPGKAGERGVPGPPGAVGPAGKDGEA------------GAQGPPG----------- 623

Query: 327  RTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG------- 379
              P G   E G +G  G PG  G PG AGPPG    PG  G+P  +   GP+G       
Sbjct: 624  --PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681

Query: 380  PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGP 433
            P  + V GP GP GP G +G PG DG  GD G  G PG  G  G  G PG+       GP
Sbjct: 682  PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741

Query: 434  KGDKGDPG----------------VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFG 477
            KGD+GD G                 G  GPPGP G PG  G S            G+   
Sbjct: 742  KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801

Query: 478  GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGL 536
                   GP GF GPPG  G PG  GEPG  G    +  PGPAG  G PG   P G  G 
Sbjct: 802  RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG---PIGNVGA 858

Query: 537  PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 596
            PG  G  G  GPPG TG  G+ G  G PG  G+ G PGP G  G+ G  G  G  GP G 
Sbjct: 859  PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGR 918

Query: 597  PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLP 650
            PG  GPPGP  PAG     G+ GP  + A    GPQG  G      LPG +G+ G PGLP
Sbjct: 919  PGEVGPPGPPGPAGEKGSPGADGP--AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976

Query: 651  GAKGEVG------ADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-------- 696
            G  GE G      A G  G PG  G  G+AGP G  G  G+ G +G PG+DG        
Sbjct: 977  GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR 1036

Query: 697  -----VGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750
                  G PG PG PG PGPV    +  D       GP G  G  G  GPAGP+G  G K
Sbjct: 1037 GETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096

Query: 751  GERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 810
            GE G  G +G KG  G  FS   G  GP   G  G PG +GP G  G  G +G  G  G 
Sbjct: 1097 GETGEQGDRGIKGHRG--FS---GLQGPP--GPPGSPGEQGPSGASGPAGPRGPPGSAGA 1149

Query: 811  PGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPP 870
            PG+ G+NGL G  G PG      G  G  GP GPPGPPGPPG P   S  F  S  P PP
Sbjct: 1150 PGKDGLNGLPGPIGPPGPR----GRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPP 1205

Query: 871  GLPGNQG 877
                + G
Sbjct: 1206 QEKAHDG 1212



 Score =  242 bits (618), Expect = 2e-63
 Identities = 163/426 (38%), Positives = 180/426 (42%), Gaps = 64/426 (15%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G  G+SG          R   G   +P  P P     PP A G   +     E  +    
Sbjct: 779  GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG---QPGAKGEPGDAGAK 835

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 365
               G     G        G+V  PG +   G   G  G  G PG  GR GPPG     GP
Sbjct: 836  GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA-GPPGATGFPGAAGRVGPPGPSGNAGP 894

Query: 366  PGLPCPVSPLGPAGPALQTVP-------GPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 415
            PG P P    G  GP  +T P       GP GPPGP G  G+PG DG  G PG  G    
Sbjct: 895  PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954

Query: 416  ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 465
                     PG  G +GFPG PG  G  G +G  G  GERGPPGP GPPG  GP     +
Sbjct: 955  AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGR 1014

Query: 466  LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGV-------NSSDVPGP 518
                  EGS         +G RG  GP GPPG PG PG PG  G          +   GP
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074

Query: 519  AGLPGVPGREGPPG------------------------FPGLPGPPGPPG---REGPPGR 551
            AG  G  G  GP G                        F GL GPPGPPG    +GP G 
Sbjct: 1075 AGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134

Query: 552  TGQ---KGSLGEAGAPGHKGSKGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGP 605
            +G    +G  G AGAPG  G  G PGP G    RG +G AG  GP GPPGPPGPPGPP  
Sbjct: 1135 SGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194

Query: 606  GLPAGF 611
            G    F
Sbjct: 1195 GFDFSF 1200


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  543 bits (1398), Expect = e-154
 Identities = 372/895 (41%), Positives = 424/895 (47%), Gaps = 185/895 (20%)

Query: 315  GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 370
            G   V+   G    PG +   G    Q G+PG+PG PGR G    PG P LPG PGLP  
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694

Query: 371  PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 415
            P S   P  P   L   PGP+G    PGPPG  GTPGR   +G PG PG  G        
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 416  -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 455
             PG  GP G PG  G +GPKGD+G PG                   VG  G PGP GPPG
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
             PG          I ++G           GP G PGP G PG+ G+PGE G  G    DV
Sbjct: 815  LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 516  PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 551
            PGP       G+PG PG  GPPG PGLP                  GPPGPPG  G PGR
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 552  TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 603
            +G  G  G+ G  G  G  G  G  G++GE GL G PGP  P         G PG PG P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 604  GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662
            G   P G+  + G  G P  S      GP GP G PGL G PG+ G PG KG +G  G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 663  GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 712
            G  G+   PG  G+ G  G  G  G +G+KGDPG   +G PGLPGP G PG       P 
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 713  VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 751
            +  S  D  +  +PG  G       PGF G PGP GPK               G +G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 752  ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 810
              G PGP GEKG+PG       G  GPA QKG  G+PGF G PGP G PG  G+ G  G 
Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209

Query: 811  PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--PGPPGTPVYDSNVFAESSRP 867
            PG PG  GL G KGEPG    GF G++G PGPPG PGP   GP G P            P
Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNP-------GPQGPP 1260

Query: 868  GPPGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921
            G PGLPG +GPP      G KG KG  G PG PG       Q    ++G  G  G  G K
Sbjct: 1261 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1320

Query: 922  GERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--IRGQPGPPGP 969
            G+ G PG  GF G    S +PG  GP       GP G PG+PGP G+S  I+G  GPPG 
Sbjct: 1321 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1380

Query: 970  QGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--------------------RQTISVPGP 1008
             G PG+ G  G QGP G PGP GPP  PG +                      T  + GP
Sbjct: 1381 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1440

Query: 1009 PGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1060
            PGP    GPPGPPGT   + G  +  TR +      + P+G L        LYV+
Sbjct: 1441 PGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSLLYVQ 1493



 Score =  535 bits (1377), Expect = e-151
 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%)

Query: 243  DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302
            D  G  G+ G          R   G    P LP  P    PP   G   +D        +
Sbjct: 39   DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89

Query: 303  TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 360
                  G    PG+  +    G    PG +   G  G KG++G PG PG PG  GPPG P
Sbjct: 90   GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 417
             +PG  G P  +         + ++PGP+G    PGPPG  G PG  G PG  G  G PG
Sbjct: 150  GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 418  DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 442
              GP G PG PG          GPKG+KG+ G+                           
Sbjct: 202  LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 443  --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 497
              G+RGPPGP   +GPPGPPG   + +K      +G           G  G PG PG PG
Sbjct: 262  LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 498  VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 534
             PG PGEPGR G       +  PGP                    GLPG+PG +G  GFP
Sbjct: 317  DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 535  GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 586
            G+ GPPG P        G  GPPG  G++G  G+ G PG     G PG  G  G  GL G
Sbjct: 377  GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435

Query: 587  APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 634
             PGPAGP          PGPPGPPG PG     G   ++G  G   F        GP G 
Sbjct: 436  PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 635  PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 682
            PGLPGL G PG  G PG KGE       G  G+PG PG PG  G  G +G  GD      
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 683  -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731
             +G +GE G PG  G+          G PGLPGP G PG + +  E+        GP G 
Sbjct: 556  MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607

Query: 732  PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 790
            PG  G PG  GP G  G     G PGP GEKG  G   +P      P   G KG+PG   
Sbjct: 608  PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659

Query: 791  ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 837
               G PG  G PG  G++G    PG PG+PG+ G+ G KGEPG   +G        G  G
Sbjct: 660  TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719

Query: 838  MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 887
            +PGPPG P         GPPGPPG P       FA    PGPPGLPG +G  GPKG +G 
Sbjct: 720  IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779

Query: 888  VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 947
             GPPGPPG+   D L       G KGD G  GQ G  G PG  G      PGPPG PGP 
Sbjct: 780  PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 948  GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 998
            G PG+ G  GE  +G PGPPG    GPPG  G  G  G PGP GPPG P  PG       
Sbjct: 834  GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891

Query: 999  --HRQTISVPGPPGPPGPPGPPGTMG 1022
               +  + + GPPGPPGP G PG  G
Sbjct: 892  PGTKGEMGMMGPPGPPGPLGIPGRSG 917



 Score =  528 bits (1360), Expect = e-149
 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%)

Query: 328  TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 387
            +PG +    G+KG+KGE G PG  G  G PG P   GPPG        G  GP     PG
Sbjct: 33   SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87

Query: 388  PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 447
            P+G  GPPG  G PG  G PG PG DG P   GPQG PG  G  G +G  G PG      
Sbjct: 88   PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139

Query: 448  PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 507
            PG QGPPGPPG            M+G      + +L GP+G PG PGPPG+ GLPG  G 
Sbjct: 140  PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189

Query: 508  FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 553
                   +PGP G PG PG  GPPG PGLPGP               G  G +GPPG  G
Sbjct: 190  -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242

Query: 554  Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 596
            Q                +G  G+ G PG  G +G PG P G +GE G  G PG  G PG 
Sbjct: 243  QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302

Query: 597  PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 644
             G  G PG PGLP G     G  G      +  D GP GPPGL           G KG+ 
Sbjct: 303  DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361

Query: 645  GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 697
            G+PGLPG KGE G  G+ G PGLPG  G A  GP GP G  G RG+KGD G  G+     
Sbjct: 362  GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 698  -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750
                   G PGLPGPPGP GP +  S++    +  PGP G PG  G  G  G +G  G K
Sbjct: 422  PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 751  GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803
            G+        G  GP G+ G PG +  P G    P QKG KG+ G  GP G  G PG  G
Sbjct: 478  GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536

Query: 804  EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 854
              GFPG  G        PGM G KGE G PG   L  G+ G PG  G PG PGP G P  
Sbjct: 537  APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595

Query: 855  VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914
            +           PG PGLPGN GP GP G     GPPGP G+     +       G  G 
Sbjct: 596  ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 915  RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 966
            +GD G    Q G+ G PG  G  G   LPG PG PG  G PGIPG KGE      G PGP
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 967  PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1019
            PGP+G PGI   G  G PG P      GPPGPP FPGP  +   ++PGPPGPPG PG  G
Sbjct: 712  PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 1020 TMG 1022
             +G
Sbjct: 770  ALG 772



 Score =  442 bits (1137), Expect = e-123
 Identities = 277/640 (43%), Positives = 316/640 (49%), Gaps = 79/640 (12%)

Query: 314  PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 364
            PG   +    G    PG  V   G  G++G PG+PG PG  GPPGSP LPG         
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893

Query: 365  ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 414
                     PPG P P+   G +G P L+   G QG PG PG  G  G  GEPG PG  G
Sbjct: 894  TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 415  --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 462
                      G+ G  G PG PG  GPKG +G PG     G  G PG  GPPGP G    
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013

Query: 463  HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 519
              +   I   G  G  GD+    GP+G  GPPGP GVPG PG PG  G    D   P   
Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071

Query: 520  --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577
              GLPG+PG +G PG PG PG PG  G  G PG  G  G+ G  G PG  G  G PGP G
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 578  ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 631
             +G SG  G PG  G PGP      PG PGPPG     G D + G  G      +   G 
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 632  QGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGE 688
             GPPGLPGL   KGD G+PG+PG  G  G  G PGF G PG +G  GP G  G     G 
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP-ALEGP 1250

Query: 689  KGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNL 747
            KG+PG  G  G+PGLPGP GPPG        +G +    G  G+PG  G PG  G +G  
Sbjct: 1251 KGNPGPQGPPGRPGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1305

Query: 748  GSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGPYGRPG-- 800
            G +G  G PG  G KG+PG    P      G +  P   G +GEPG  GPPGP G PG  
Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1365

Query: 801  -----YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV 855
                  KG+ G PG PG+PG+ GL G +G           +G+PGP GPPG PG  G P 
Sbjct: 1366 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDPGRNGLPG 1415

Query: 856  YDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895
            +D         PG PG PG +G  GP G  G  GPPGPPG
Sbjct: 1416 FD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  399 bits (1026), Expect = e-111
 Identities = 256/609 (42%), Positives = 291/609 (47%), Gaps = 112/609 (18%)

Query: 265  ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 324
            E G+  +P LP PP    P L G      S+ E+ E        G   +PG      + G
Sbjct: 939  EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985

Query: 325  SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 383
                PG    + GL GQ G PG PGP G  G PG P L GPPGL   +  +G  GP  ++
Sbjct: 986  LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 384  TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 438
              PGP G PG PG  G PG+ G+ GDPG       G PG  G  G PG PG+ G KG  G
Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101

Query: 439  DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491
            DPG+       G +G PG  G PG PGP                         GP+G  G
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137

Query: 492  PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 549
            PPG PG+PG PG  G  G      PGP G  G PG++G PG  G  G PG P  G  GPP
Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195

Query: 550  GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 609
            G  G  G  G+ G PG  G+ G PGP   +GE G  G PG  GPPGPPG PGP       
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGP------- 1245

Query: 610  GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPG 669
              +  +G+ GP         GP G PGLPG +G PG+PG  G KGE G  G PG PGLPG
Sbjct: 1246 ALEGPKGNPGP--------QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297

Query: 670  REGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSV 725
             +G  GP   QG  G  G  G KGDPG  GV G PG+ GP G PG               
Sbjct: 1298 LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------------- 1344

Query: 726  PGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAK 784
             GPEG PG  G PGP G  G  G S   +G  GP G  G+PG              KG  
Sbjct: 1345 -GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG-------------LKGLP 1390

Query: 785  GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 844
            G  G +G PGP G PG  G  G PG  G  G  G  G  G+PG      G+ G PGP G 
Sbjct: 1391 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR----GLDGPPGPDGL 1446

Query: 845  PGPPGPPGT 853
             GPPGPPGT
Sbjct: 1447 QGPPGPPGT 1455



 Score =  398 bits (1022), Expect = e-110
 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%)

Query: 425  PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 483
            PG+  D  G KG+KG     ERG PG +G PG PG                         
Sbjct: 34   PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64

Query: 484  RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 543
             GP G PGP G  G  G+PG PG  G+      GP GLPG PG    PG PG+PG  G P
Sbjct: 65   PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116

Query: 544  GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 597
            G +G PG  G KG  G  G+PG  G +G PGP G  G  G  G+      PGP G PG P
Sbjct: 117  GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176

Query: 598  GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 657
            GPPG  G   P G                   GP GPPG PGL G PG PGLPG KG +G
Sbjct: 177  GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219

Query: 658  ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 701
             +   G  G  G +G+ GP GP                KGD+G  G++G PG      PG
Sbjct: 220  LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273

Query: 702  LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 756
            + GPPGPPG       + G           G  G+PG  G PG  G  G  G  GE+G  
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 757  GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 804
            G  G  G PG +    G        G +G    P +KG +G PG +GPPG  G PG    
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392

Query: 805  IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863
            +G PG PG PG  G KG++G PG +  G  G+ G PG PG PGPPGP G  +  S+   E
Sbjct: 393  MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452

Query: 864  SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 910
               PGPPG PG++G  G +G KG+ G             PPG PG              G
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 911  EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 950
            +KG++G AG  G +G       PG  GF GS        + PG  G       PG  G P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 951  GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1009
            G+PG  G+   G PG PGP+G PG I ++G +GPPG PG PG P   GP        GPP
Sbjct: 573  GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623

Query: 1010 G--PPGPPGPPGTMGAS 1024
            G  PPGP G  G  G +
Sbjct: 624  GFGPPGPVGEKGIQGVA 640



 Score =  386 bits (992), Expect = e-107
 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%)

Query: 500  GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558
            G P E    +G +       +G+ G  G  G PG  G PG PG PG EGPPG  GQKG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 559  GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618
            G  G PG KG +G PG  G  G  GL G PG  G PGP G PG  G     GF    G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 619  GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 675
            G          GP GPPG+PG+KG+PG   +  LPG KG  G  G PG  GLPG  GI G
Sbjct: 141  G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 676  PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 712
            P GP G  G  G  G PG  G                G+ GL GPPGPPG +        
Sbjct: 193  PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 713  VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 768
            V   + D  +    GP G PG  G PGP     G KG  G  G+RG PG  GE G+PG  
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 769  FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 804
              P D G  G P + G KG+ G  GPPGP                       G PG KGE
Sbjct: 313  GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 805  IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 843
             GFP                 G PG PG  G +G+KG+ G   +      G+ G PG PG
Sbjct: 373  RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432

Query: 844  PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 890
             PGPPGP G  +  S+   E   PGPPG PG++G  G +G KG+              GP
Sbjct: 433  LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 891  PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 935
            PG PG              G+KG++G AG  G +      G PG  GF GS         
Sbjct: 493  PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 936  -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 974
                              LPG PG PG  G PG+PGPKGE    + +G+ GPPG  G PG
Sbjct: 553  FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 975  I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1016
            + G  G  GPP  GPPGP            PG P  PGP     QTI+ PG PG PG PG
Sbjct: 613  LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672

Query: 1017 PPGTMG 1022
              G +G
Sbjct: 673  RDGDVG 678



 Score =  243 bits (621), Expect = 7e-64
 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%)

Query: 681  GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740
            G +G +GE+G PG +G   PGLPG PGP GP              PGP G+ G  G PGP
Sbjct: 42   GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85

Query: 741  AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800
             GPKG  G  G  G PG  G  G PG   +P    + P   G KGE GF G PG  G  G
Sbjct: 86   PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144

Query: 801  YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857
              G  G PG  G PG   M+ L G KG PG      G++G+PGP G PGP GPPG P   
Sbjct: 145  PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200

Query: 858  SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 909
                     PGPPGLPG         QGP G KG +G  GPPGPPGQ       ++ E  
Sbjct: 201  ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255

Query: 910  GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 968
                      QKG++G PG  G        PPGPPG RG PG PG  KGE  +G+ G PG
Sbjct: 256  ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295

Query: 969  PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
             +G PG   +G  G PG PG PG P +PG P R      G  G  GPPGPPG +    G 
Sbjct: 296  KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 1028 RLWATRQAMLG 1038
             +    +  +G
Sbjct: 352  GITIGEKGNIG 362



 Score =  157 bits (398), Expect = 5e-38
 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%)

Query: 817  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876
            +G+KGEKGE G   L  G  G+PG PGP GPPGP G          +   PGPPG  G +
Sbjct: 41   SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92

Query: 877  GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936
            GPPG  G  G  G PG PG              G +G  G  G KGERG PG  GF    
Sbjct: 93   GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139

Query: 937  LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 996
             PG  GPPGP G PG+ G  G  I      PGP+G PG       GPPG  G PGP   P
Sbjct: 140  -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191

Query: 997  GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1054
            GP    I  PGPPG  GPPGPPG  G   + G+     +     Q  + P G    ++EQ
Sbjct: 192  GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247

Query: 1055 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1113
            +  + V  Q G      +   P  RG         PP     +      +  P    +P 
Sbjct: 248  KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301

Query: 1114 R-ADDILASPPRLPEPQPYPGAP 1135
            +  ++     P LP    YPG P
Sbjct: 302  KDGENGQPGIPGLPGDPGYPGEP 324


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  541 bits (1394), Expect = e-153
 Identities = 373/901 (41%), Positives = 425/901 (47%), Gaps = 194/901 (21%)

Query: 315  GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 370
            G   V+   G    PG +   G    Q G+PG+PG PGR G    PG P LPG PGLP  
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694

Query: 371  PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 415
            P S   P  P   L   PGP+G    PGPPG  GTPGR   +G PG PG  G        
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 416  -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 455
             PG  GP G PG  G +GPKGD+G PG                   VG  G PGP GPPG
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
             PG          I ++G           GP G PGP G PG+ G+PGE G  G    DV
Sbjct: 815  LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 516  PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 551
            PGP       G+PG PG  GPPG PGLP                  GPPGPPG  G PGR
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 552  TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 603
            +G  G  G+ G  G  G  G  G  G++GE GL G PGP  P         G PG PG P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 604  GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662
            G   P G+  + G  G P  S      GP GP G PGL G PG+ G PG KG +G  G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 663  GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 712
            G  G+   PG  G+ G  G  G  G +G+KGDPG   +G PGLPGP G PG       P 
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 713  VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 751
            +  S  D  +  +PG  G       PGF G PGP GPK               G +G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 752  ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 810
              G PGP GEKG+PG       G  GPA QKG  G+PGF G PGP G PG  G+ G  G 
Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209

Query: 811  PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--------PGPPGTPVYDSNVF 861
            PG PG  GL G KGEPG    GF G++G PGPPG PGP        PGP G P       
Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP------- 1260

Query: 862  AESSRPGPPGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 915
                RPG  GLPG +GPP      G KG KG  G PG PG       Q    ++G  G  
Sbjct: 1261 ---GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1317

Query: 916  GDAGQKGERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--IRGQ 963
            G  G KG+ G PG  GF G    S +PG  GP       GP G PG+PGP G+S  I+G 
Sbjct: 1318 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1377

Query: 964  PGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--------------------RQT 1002
             GPPG  G PG+ G  G QGP G PGP GPP  PG +                      T
Sbjct: 1378 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT 1437

Query: 1003 ISVPGPPGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYV 1059
              + GPPGP    GPPGPPGT   + G  +  TR +      + P+G L        LYV
Sbjct: 1438 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSLLYV 1495

Query: 1060 R 1060
            +
Sbjct: 1496 Q 1496



 Score =  535 bits (1377), Expect = e-151
 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%)

Query: 243  DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302
            D  G  G+ G          R   G    P LP  P    PP   G   +D        +
Sbjct: 39   DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89

Query: 303  TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 360
                  G    PG+  +    G    PG +   G  G KG++G PG PG PG  GPPG P
Sbjct: 90   GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 417
             +PG  G P  +         + ++PGP+G    PGPPG  G PG  G PG  G  G PG
Sbjct: 150  GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 418  DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 442
              GP G PG PG          GPKG+KG+ G+                           
Sbjct: 202  LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 443  --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 497
              G+RGPPGP   +GPPGPPG   + +K      +G           G  G PG PG PG
Sbjct: 262  LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 498  VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 534
             PG PGEPGR G       +  PGP                    GLPG+PG +G  GFP
Sbjct: 317  DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 535  GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 586
            G+ GPPG P        G  GPPG  G++G  G+ G PG     G PG  G  G  GL G
Sbjct: 377  GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435

Query: 587  APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 634
             PGPAGP          PGPPGPPG PG     G   ++G  G   F        GP G 
Sbjct: 436  PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 635  PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 682
            PGLPGL G PG  G PG KGE       G  G+PG PG PG  G  G +G  GD      
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 683  -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731
             +G +GE G PG  G+          G PGLPGP G PG + +  E+        GP G 
Sbjct: 556  MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607

Query: 732  PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 790
            PG  G PG  GP G  G     G PGP GEKG  G   +P      P   G KG+PG   
Sbjct: 608  PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659

Query: 791  ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 837
               G PG  G PG  G++G    PG PG+PG+ G+ G KGEPG   +G        G  G
Sbjct: 660  TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719

Query: 838  MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 887
            +PGPPG P         GPPGPPG P       FA    PGPPGLPG +G  GPKG +G 
Sbjct: 720  IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779

Query: 888  VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 947
             GPPGPPG+   D L       G KGD G  GQ G  G PG  G      PGPPG PGP 
Sbjct: 780  PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 948  GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 998
            G PG+ G  GE  +G PGPPG    GPPG  G  G  G PGP GPPG P  PG       
Sbjct: 834  GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891

Query: 999  --HRQTISVPGPPGPPGPPGPPGTMG 1022
               +  + + GPPGPPGP G PG  G
Sbjct: 892  PGTKGEMGMMGPPGPPGPLGIPGRSG 917



 Score =  528 bits (1360), Expect = e-149
 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%)

Query: 328  TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 387
            +PG +    G+KG+KGE G PG  G  G PG P   GPPG        G  GP     PG
Sbjct: 33   SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87

Query: 388  PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 447
            P+G  GPPG  G PG  G PG PG DG P   GPQG PG  G  G +G  G PG      
Sbjct: 88   PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139

Query: 448  PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 507
            PG QGPPGPPG            M+G      + +L GP+G PG PGPPG+ GLPG  G 
Sbjct: 140  PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189

Query: 508  FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 553
                   +PGP G PG PG  GPPG PGLPGP               G  G +GPPG  G
Sbjct: 190  -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242

Query: 554  Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 596
            Q                +G  G+ G PG  G +G PG P G +GE G  G PG  G PG 
Sbjct: 243  QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302

Query: 597  PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 644
             G  G PG PGLP G     G  G      +  D GP GPPGL           G KG+ 
Sbjct: 303  DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361

Query: 645  GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 697
            G+PGLPG KGE G  G+ G PGLPG  G A  GP GP G  G RG+KGD G  G+     
Sbjct: 362  GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 698  -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750
                   G PGLPGPPGP GP +  S++    +  PGP G PG  G  G  G +G  G K
Sbjct: 422  PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 751  GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803
            G+        G  GP G+ G PG +  P G    P QKG KG+ G  GP G  G PG  G
Sbjct: 478  GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536

Query: 804  EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 854
              GFPG  G        PGM G KGE G PG   L  G+ G PG  G PG PGP G P  
Sbjct: 537  APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595

Query: 855  VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914
            +           PG PGLPGN GP GP G     GPPGP G+     +       G  G 
Sbjct: 596  ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 915  RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 966
            +GD G    Q G+ G PG  G  G   LPG PG PG  G PGIPG KGE      G PGP
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 967  PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1019
            PGP+G PGI   G  G PG P      GPPGPP FPGP  +   ++PGPPGPPG PG  G
Sbjct: 712  PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 1020 TMG 1022
             +G
Sbjct: 770  ALG 772



 Score =  437 bits (1125), Expect = e-122
 Identities = 275/644 (42%), Positives = 317/644 (49%), Gaps = 84/644 (13%)

Query: 314  PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 364
            PG   +    G    PG  V   G  G++G PG+PG PG  GPPGSP LPG         
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893

Query: 365  ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 414
                     PPG P P+   G +G P L+   G QG PG PG  G  G  GEPG PG  G
Sbjct: 894  TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 415  --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 462
                      G+ G  G PG PG  GPKG +G PG     G  G PG  GPPGP G    
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013

Query: 463  HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 519
              +   I   G  G  GD+    GP+G  GPPGP GVPG PG PG  G    D   P   
Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071

Query: 520  --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577
              GLPG+PG +G PG PG PG PG  G  G PG  G  G+ G  G PG  G  G PGP G
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 578  ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 631
             +G SG  G PG  G PGP      PG PGPPG     G D + G  G      +   G 
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 632  QGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP-----KGDR 683
             GPPGLPGL   KGD G+PG+PG  G  G  G PGF G PG +G  GP G      +G +
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 684  GSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGP 743
            G+ G +G PG+ G    GLPGP GPPG        +G +    G  G+PG  G PG  G 
Sbjct: 1252 GNPGPQGPPGRPGF--QGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGLKGD 1304

Query: 744  KGNLGSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGPYGR 798
            +G  G +G  G PG  G KG+PG    P      G +  P   G +GEPG  GPPGP G 
Sbjct: 1305 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1364

Query: 799  PG-------YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPP 851
            PG        KG+ G PG PG+PG+ GL G +G           +G+PGP GPPG PG  
Sbjct: 1365 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDPGRN 1414

Query: 852  GTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895
            G P +D         PG PG PG +G  GP G  G  GPPGPPG
Sbjct: 1415 GLPGFD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  398 bits (1022), Expect = e-110
 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%)

Query: 425  PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 483
            PG+  D  G KG+KG     ERG PG +G PG PG                         
Sbjct: 34   PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64

Query: 484  RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 543
             GP G PGP G  G  G+PG PG  G+      GP GLPG PG    PG PG+PG  G P
Sbjct: 65   PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116

Query: 544  GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 597
            G +G PG  G KG  G  G+PG  G +G PGP G  G  G  G+      PGP G PG P
Sbjct: 117  GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176

Query: 598  GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 657
            GPPG  G   P G                   GP GPPG PGL G PG PGLPG KG +G
Sbjct: 177  GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219

Query: 658  ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 701
             +   G  G  G +G+ GP GP                KGD+G  G++G PG      PG
Sbjct: 220  LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273

Query: 702  LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 756
            + GPPGPPG       + G           G  G+PG  G PG  G  G  G  GE+G  
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 757  GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 804
            G  G  G PG +    G        G +G    P +KG +G PG +GPPG  G PG    
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392

Query: 805  IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863
            +G PG PG PG  G KG++G PG +  G  G+ G PG PG PGPPGP G  +  S+   E
Sbjct: 393  MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452

Query: 864  SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 910
               PGPPG PG++G  G +G KG+ G             PPG PG              G
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 911  EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 950
            +KG++G AG  G +G       PG  GF GS        + PG  G       PG  G P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 951  GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1009
            G+PG  G+   G PG PGP+G PG I ++G +GPPG PG PG P   GP        GPP
Sbjct: 573  GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623

Query: 1010 G--PPGPPGPPGTMGAS 1024
            G  PPGP G  G  G +
Sbjct: 624  GFGPPGPVGEKGIQGVA 640



 Score =  394 bits (1011), Expect = e-109
 Identities = 259/615 (42%), Positives = 294/615 (47%), Gaps = 121/615 (19%)

Query: 265  ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 324
            E G+  +P LP PP    P L G      S+ E+ E        G   +PG      + G
Sbjct: 939  EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985

Query: 325  SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 383
                PG    + GL GQ G PG PGP G  G PG P L GPPGL   +  +G  GP  ++
Sbjct: 986  LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 384  TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 438
              PGP G PG PG  G PG+ G+ GDPG       G PG  G  G PG PG+ G KG  G
Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101

Query: 439  DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491
            DPG+       G +G PG  G PG PGP                         GP+G  G
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137

Query: 492  PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 549
            PPG PG+PG PG  G  G      PGP G  G PG++G PG  G  G PG P  G  GPP
Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195

Query: 550  GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 609
            G  G  G  G+ G PG  G+ G PGP   +GE G  G PG  GPPGPPG PGP       
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGPA------ 1246

Query: 610  GFDDMEGSGGPFWSTARSADGPQGPP------GLPGLKGDPGVPGLPGAKGEVGADGVPG 663
                +EG  G          GPQGPP      GLPG +G PG+PG  G KGE G  G PG
Sbjct: 1247 ----LEGPKG--------NPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1294

Query: 664  FPGLPGREGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQD 719
             PGLPG +G  GP   QG  G  G  G KGDPG  GV G PG+ GP G PG         
Sbjct: 1295 LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------- 1347

Query: 720  GSVLSVPGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGP 778
                   GPEG PG  G PGP G  G  G S   +G  GP G  G+PG       G  GP
Sbjct: 1348 -------GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL-----KGLPGP 1395

Query: 779  AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 838
              +G +G PG  GPPG  GR G  G  G  GR G PG+ G  G +G          + G 
Sbjct: 1396 --QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG----------LDGP 1443

Query: 839  PGPPGPPGPPGPPGT 853
            PGP G  GPPGPPGT
Sbjct: 1444 PGPDGLQGPPGPPGT 1458



 Score =  386 bits (992), Expect = e-107
 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%)

Query: 500  GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558
            G P E    +G +       +G+ G  G  G PG  G PG PG PG EGPPG  GQKG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 559  GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618
            G  G PG KG +G PG  G  G  GL G PG  G PGP G PG  G     GF    G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 619  GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 675
            G          GP GPPG+PG+KG+PG   +  LPG KG  G  G PG  GLPG  GI G
Sbjct: 141  G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 676  PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 712
            P GP G  G  G  G PG  G                G+ GL GPPGPPG +        
Sbjct: 193  PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 713  VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 768
            V   + D  +    GP G PG  G PGP     G KG  G  G+RG PG  GE G+PG  
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 769  FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 804
              P D G  G P + G KG+ G  GPPGP                       G PG KGE
Sbjct: 313  GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 805  IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 843
             GFP                 G PG PG  G +G+KG+ G   +      G+ G PG PG
Sbjct: 373  RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432

Query: 844  PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 890
             PGPPGP G  +  S+   E   PGPPG PG++G  G +G KG+              GP
Sbjct: 433  LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 891  PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 935
            PG PG              G+KG++G AG  G +      G PG  GF GS         
Sbjct: 493  PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 936  -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 974
                              LPG PG PG  G PG+PGPKGE    + +G+ GPPG  G PG
Sbjct: 553  FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 975  I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1016
            + G  G  GPP  GPPGP            PG P  PGP     QTI+ PG PG PG PG
Sbjct: 613  LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672

Query: 1017 PPGTMG 1022
              G +G
Sbjct: 673  RDGDVG 678



 Score =  243 bits (621), Expect = 7e-64
 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%)

Query: 681  GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740
            G +G +GE+G PG +G   PGLPG PGP GP              PGP G+ G  G PGP
Sbjct: 42   GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85

Query: 741  AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800
             GPKG  G  G  G PG  G  G PG   +P    + P   G KGE GF G PG  G  G
Sbjct: 86   PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144

Query: 801  YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857
              G  G PG  G PG   M+ L G KG PG      G++G+PGP G PGP GPPG P   
Sbjct: 145  PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200

Query: 858  SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 909
                     PGPPGLPG         QGP G KG +G  GPPGPPGQ       ++ E  
Sbjct: 201  ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255

Query: 910  GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 968
                      QKG++G PG  G        PPGPPG RG PG PG  KGE  +G+ G PG
Sbjct: 256  ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295

Query: 969  PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
             +G PG   +G  G PG PG PG P +PG P R      G  G  GPPGPPG +    G 
Sbjct: 296  KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 1028 RLWATRQAMLG 1038
             +    +  +G
Sbjct: 352  GITIGEKGNIG 362



 Score =  157 bits (398), Expect = 5e-38
 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%)

Query: 817  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876
            +G+KGEKGE G   L  G  G+PG PGP GPPGP G          +   PGPPG  G +
Sbjct: 41   SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92

Query: 877  GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936
            GPPG  G  G  G PG PG              G +G  G  G KGERG PG  GF    
Sbjct: 93   GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139

Query: 937  LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 996
             PG  GPPGP G PG+ G  G  I      PGP+G PG       GPPG  G PGP   P
Sbjct: 140  -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191

Query: 997  GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1054
            GP    I  PGPPG  GPPGPPG  G   + G+     +     Q  + P G    ++EQ
Sbjct: 192  GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247

Query: 1055 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1113
            +  + V  Q G      +   P  RG         PP     +      +  P    +P 
Sbjct: 248  KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301

Query: 1114 R-ADDILASPPRLPEPQPYPGAP 1135
            +  ++     P LP    YPG P
Sbjct: 302  KDGENGQPGIPGLPGDPGYPGEP 324


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  540 bits (1391), Expect = e-153
 Identities = 374/904 (41%), Positives = 426/904 (47%), Gaps = 197/904 (21%)

Query: 315  GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLP-C 370
            G   V+   G    PG +   G    Q G+PG+PG PGR G    PG P LPG PGLP  
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGI 694

Query: 371  PVSPLGPAGPA--LQTVPGPQGP---PGPPGRDGTPGR---DGEPGDPGEDGK------- 415
            P S   P  P   L   PGP+G    PGPPG  GTPGR   +G PG PG  G        
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 416  -PGDTGPQGFPGTPGDVGPKGDKGDPG-------------------VGERGPPGPQGPPG 455
             PG  GP G PG  G +GPKGD+G PG                   VG  G PGP GPPG
Sbjct: 755  LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
             PG          I ++G           GP G PGP G PG+ G+PGE G  G    DV
Sbjct: 815  LPG----------IGVQGP---------PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 516  PGP------AGLPGVPGREGPPGFPGLP------------------GPPGPPGREGPPGR 551
            PGP       G+PG PG  GPPG PGLP                  GPPGPPG  G PGR
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 552  TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP--------PGPPGPPGPP 603
            +G  G  G+ G  G  G  G  G  G++GE GL G PGP  P         G PG PG P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 604  GPGLPAGFDDMEGS-GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662
            G   P G+  + G  G P  S      GP GP G PGL G PG+ G PG KG +G  G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 663  GFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG-------PV 712
            G  G+   PG  G+ G  G  G  G +G+KGDPG   +G PGLPGP G PG       P 
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 713  VYVSEQDGSVLSVPGPEGR------PGFAGFPGPAGPK---------------GNLGSKG 751
            +  S  D  +  +PG  G       PGF G PGP GPK               G +G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 752  ERGSPGPKGEKGEPGSIFSPDGGALGPA-QKGAKGEPGFRGPPGPYGRPGYKGEIGFPGR 810
              G PGP GEKG+PG       G  GPA QKG  G+PGF G PGP G PG  G+ G  G 
Sbjct: 1156 HPGQPGPPGEKGKPG-----QDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGL 1209

Query: 811  PGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGP--------PGPPGTPVYDSNVF 861
            PG PG  GL G KGEPG    GF G++G PGPPG PGP        PGP G P       
Sbjct: 1210 PGIPGNPGLPGPKGEPG--FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP------- 1260

Query: 862  AESSRPGP---PGLPGNQGPP------GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912
                RPGP    GLPG +GPP      G KG KG  G PG PG       Q    ++G  
Sbjct: 1261 ---GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1317

Query: 913  GDRGDAGQKGERGEPGGGGFFG----SSLPGPPGPP------GPRGYPGIPGPKGES--I 960
            G  G  G KG+ G PG  GF G    S +PG  GP       GP G PG+PGP G+S  I
Sbjct: 1318 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1377

Query: 961  RGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH-------------------- 999
            +G  GPPG  G PG+ G  G QGP G PGP GPP  PG +                    
Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ 1437

Query: 1000 RQTISVPGPPGP---PGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEE 1056
              T  + GPPGP    GPPGPPGT   + G  +  TR +      + P+G L        
Sbjct: 1438 PGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLI--TRHSQTTDAPQCPQGTLQVYEGFSL 1495

Query: 1057 LYVR 1060
            LYV+
Sbjct: 1496 LYVQ 1499



 Score =  535 bits (1377), Expect = e-151
 Identities = 365/926 (39%), Positives = 421/926 (45%), Gaps = 193/926 (20%)

Query: 243  DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302
            D  G  G+ G          R   G    P LP  P    PP   G   +D        +
Sbjct: 39   DCSGIKGEKGE---------RGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPK 89

Query: 303  TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSP 360
                  G    PG+  +    G    PG +   G  G KG++G PG PG PG  GPPG P
Sbjct: 90   GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP 149

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 417
             +PG  G P  +         + ++PGP+G    PGPPG  G PG  G PG  G  G PG
Sbjct: 150  GIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 418  DTGPQGFPGTPGD--------VGPKGDKGDPGV--------------------------- 442
              GP G PG PG          GPKG+KG+ G+                           
Sbjct: 202  LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 443  --GERGPPGP---QGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPG 497
              G+RGPPGP   +GPPGPPG   + +K      +G           G  G PG PG PG
Sbjct: 262  LPGDRGPPGPPGIRGPPGPPGGE-KGEK----GEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 498  VPGLPGEPGRFG----VNSSDVPGP-------------------AGLPGVPGREGPPGFP 534
             PG PGEPGR G       +  PGP                    GLPG+PG +G  GFP
Sbjct: 317  DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP 376

Query: 535  GLPGPPGPP--------GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG 586
            G+ GPPG P        G  GPPG  G++G  G+ G PG     G PG  G  G  GL G
Sbjct: 377  GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAPGLPG 435

Query: 587  APGPAGP----------PGPPGPPGPPGPGLPAGFDDMEGSGGP--FWSTARSADGPQGP 634
             PGPAGP          PGPPGPPG PG     G   ++G  G   F        GP G 
Sbjct: 436  PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 635  PGLPGLKGDPGVPGLPGAKGE------VGADGVPGFPGLPGREGIAGPQGPKGD------ 682
            PGLPGL G PG  G PG KGE       G  G+PG PG PG  G  G +G  GD      
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 683  -RGSRGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731
             +G +GE G PG  G+          G PGLPGP G PG + +  E+        GP G 
Sbjct: 556  MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER--------GPPGN 607

Query: 732  PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFR- 790
            PG  G PG  GP G  G     G PGP GEKG  G   +P      P   G KG+PG   
Sbjct: 608  PGLPGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPG----QPGIPGPKGDPGQTI 659

Query: 791  ---GPPGPYGRPGYKGEIGF---PGRPGRPGMNGLKGEKGEPGDASLGF-------GMRG 837
               G PG  G PG  G++G    PG PG+PG+ G+ G KGEPG   +G        G  G
Sbjct: 660  TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719

Query: 838  MPGPPGPP---------GPPGPPGTPVYDSNV-FAESSRPGPPGLPGNQGPPGPKGAKGE 887
            +PGPPG P         GPPGPPG P       FA    PGPPGLPG +G  GPKG +G 
Sbjct: 720  IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779

Query: 888  VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 947
             GPPGPPG+   D L       G KGD G  GQ G  G PG  G      PGPPG PGP 
Sbjct: 780  PGPPGPPGRTGLDGL------PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 948  GYPGIPGPKGESIRGQPGPPG--PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP------ 998
            G PG+ G  GE  +G PGPPG    GPPG  G  G  G PGP GPPG P  PG       
Sbjct: 834  GQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891

Query: 999  --HRQTISVPGPPGPPGPPGPPGTMG 1022
               +  + + GPPGPPGP G PG  G
Sbjct: 892  PGTKGEMGMMGPPGPPGPLGIPGRSG 917



 Score =  528 bits (1360), Expect = e-149
 Identities = 344/783 (43%), Positives = 387/783 (49%), Gaps = 131/783 (16%)

Query: 328  TPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG 387
            +PG +    G+KG+KGE G PG  G  G PG P   GPPG        G  GP     PG
Sbjct: 33   SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP-----PG 87

Query: 388  PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGP 447
            P+G  GPPG  G PG  G PG PG DG P   GPQG PG  G  G +G  G PG      
Sbjct: 88   PKGIRGPPGLPGFPGTPGLPGMPGHDGAP---GPQGIPGCNGTKGERGFPGSPGF----- 139

Query: 448  PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR 507
            PG QGPPGPPG            M+G      + +L GP+G PG PGPPG+ GLPG  G 
Sbjct: 140  PGLQGPPGPPG---------IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG- 189

Query: 508  FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP--------------PGPPGREGPPGRTG 553
                   +PGP G PG PG  GPPG PGLPGP               G  G +GPPG  G
Sbjct: 190  -------IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242

Query: 554  Q----------------KGSLGEAGAPGHKGSKGAPG-PAGARGESGLAGAPGPAGPPGP 596
            Q                +G  G+ G PG  G +G PG P G +GE G  G PG  G PG 
Sbjct: 243  QISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302

Query: 597  PGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSAD-GPQGPPGLP----------GLKGDP 644
             G  G PG PGLP G     G  G      +  D GP GPPGL           G KG+ 
Sbjct: 303  DGENGQPGIPGLP-GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361

Query: 645  GVPGLPGAKGEVGADGVPGFPGLPGREGIA--GPQGPKGDRGSRGEKGDPGKDGV----- 697
            G+PGLPG KGE G  G+ G PGLPG  G A  GP GP G  G RG+KGD G  G+     
Sbjct: 362  GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 698  -------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSK 750
                   G PGLPGPPGP GP +  S++    +  PGP G PG  G  G  G +G  G K
Sbjct: 422  PGLDGQPGAPGLPGPPGPAGPHIPPSDE----ICEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 751  GE-------RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803
            G+        G  GP G+ G PG +  P G    P QKG KG+ G  GP G  G PG  G
Sbjct: 478  GDTCFNCIGTGISGPPGQPGLPG-LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG 536

Query: 804  EIGFPGRPGR-------PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTP-- 854
              GFPG  G        PGM G KGE G PG   L  G+ G PG  G PG PGP G P  
Sbjct: 537  APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP-GLPGTPGQDGLPGLPGPKGEPGG 595

Query: 855  VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914
            +           PG PGLPGN GP GP G     GPPGP G+     +       G  G 
Sbjct: 596  ITFKGERGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 915  RGDAG----QKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKGE---SIRGQPGP 966
            +GD G    Q G+ G PG  G  G   LPG PG PG  G PGIPG KGE      G PGP
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 967  PGPQGPPGIGYEGRQGPPGPP------GPPGPPSFPGPHRQT-ISVPGPPGPPGPPGPPG 1019
            PGP+G PGI   G  G PG P      GPPGPP FPGP  +   ++PGPPGPPG PG  G
Sbjct: 712  PGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 1020 TMG 1022
             +G
Sbjct: 770  ALG 772



 Score =  440 bits (1131), Expect = e-123
 Identities = 278/647 (42%), Positives = 315/647 (48%), Gaps = 87/647 (13%)

Query: 314  PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--------- 364
            PG   +    G    PG  V   G  G++G PG+PG PG  GPPGSP LPG         
Sbjct: 836  PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893

Query: 365  ---------PPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 414
                     PPG P P+   G +G P L+   G QG PG PG  G  G  GEPG PG  G
Sbjct: 894  TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 415  --------KPGDTGPQGFPGTPGDVGPKGDKGDPG----VGERGPPGPQGPPGPPGPSFR 462
                      G+ G  G PG PG  GPKG +G PG     G  G PG  GPPGP G    
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013

Query: 463  HDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPA-- 519
              +   I   G  G  GD+    GP+G  GPPGP GVPG PG PG  G    D   P   
Sbjct: 1014 PGQPGLIGPPGLKGTIGDM-GFPGPQGVEGPPGPSGVPGQPGSPGLPG-QKGDKGDPGIS 1071

Query: 520  --GLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577
              GLPG+PG +G PG PG PG PG  G  G PG  G  G+ G  G PG  G  G PGP G
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 578  ARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGP 631
             +G SG  G PG  G PGP      PG PGPPG     G D + G  G      +   G 
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 632  QGPPGLPGLKGD---------PGVPGLPGAKGEVGADGVPGFPGLPGREGIAGP--QGPK 680
             GPPGLPGL G          PG PGLPG KGE G  G PG  G PG  G  GP  +GPK
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 681  GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740
            G+ G +G  G PG  G    GLPGP GPPG        +G +    G  G+PG  G PG 
Sbjct: 1252 GNPGPQGPPGRPGPTGF--QGLPGPEGPPG-----LPGNGGIKGEKGNPGQPGLPGLPGL 1304

Query: 741  AGPKGNLGSKGERGSPGPKGEKGEPGSIFSP-----DGGALGPAQKGAKGEPGFRGPPGP 795
             G +G  G +G  G PG  G KG+PG    P      G +  P   G +GEPG  GPPGP
Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364

Query: 796  YGRPG-------YKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPP 848
             G PG        KG+ G PG PG+PG+ GL G +G           +G+PGP GPPG P
Sbjct: 1365 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP----------QGLPGPTGPPGDP 1414

Query: 849  GPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895
            G  G P +D         PG PG PG +G  GP G  G  GPPGPPG
Sbjct: 1415 GRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  398 bits (1022), Expect = e-110
 Identities = 267/677 (39%), Positives = 316/677 (46%), Gaps = 147/677 (21%)

Query: 425  PGTPGDV-GPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 483
            PG+  D  G KG+KG     ERG PG +G PG PG                         
Sbjct: 34   PGSKCDCSGIKGEKG-----ERGFPGLEGHPGLPG------------------------F 64

Query: 484  RGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP 543
             GP G PGP G  G  G+PG PG  G+      GP GLPG PG    PG PG+PG  G P
Sbjct: 65   PGPEGPPGPRGQKGDDGIPGPPGPKGIR-----GPPGLPGFPGT---PGLPGMPGHDGAP 116

Query: 544  GREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGA------PGPAGPPGPP 597
            G +G PG  G KG  G  G+PG  G +G PGP G  G  G  G+      PGP G PG P
Sbjct: 117  GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYP 176

Query: 598  GPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 657
            GPPG  G   P G                   GP GPPG PGL G PG PGLPG KG +G
Sbjct: 177  GPPGIQGLPGPTGIP-----------------GPIGPPGPPGLMGPPGPPGLPGPKGNMG 219

Query: 658  ADGVPGFPGLPGREGIAGPQGP----------------KGDRGSRGEKGDPGKDGVGQPG 701
             +   G  G  G +G+ GP GP                KGD+G  G++G PG      PG
Sbjct: 220  LN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP-----PG 273

Query: 702  LPGPPGPPGPVVYVSEQDGSV-----LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSP 756
            + GPPGPPG       + G           G  G+PG  G PG  G  G  G  GE+G  
Sbjct: 274  IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK 333

Query: 757  GPKGEKGEPGSIFSPDG--------GALG----PAQKGAKGEPGFRGPPGPYGRPGYKGE 804
            G  G  G PG +    G        G +G    P +KG +G PG +GPPG  G PG    
Sbjct: 334  GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAV 392

Query: 805  IGFPGRPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863
            +G PG PG PG  G KG++G PG +  G  G+ G PG PG PGPPGP G  +  S+   E
Sbjct: 393  MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452

Query: 864  SSRPGPPGLPGNQGPPGPKGAKGEVG-------------PPGPPGQFPFDFLQLEAEMKG 910
               PGPPG PG++G  G +G KG+ G             PPG PG              G
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 911  EKGDRGDAGQKGERG------EPGGGGFFGS--------SLPGPPGP------PGPRGYP 950
            +KG++G AG  G +G       PG  GF GS        + PG  G       PG  G P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 951  GIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1009
            G+PG  G+   G PG PGP+G PG I ++G +GPPG PG PG P   GP        GPP
Sbjct: 573  GLPGTPGQD--GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM-------GPP 623

Query: 1010 G--PPGPPGPPGTMGAS 1024
            G  PPGP G  G  G +
Sbjct: 624  GFGPPGPVGEKGIQGVA 640



 Score =  397 bits (1019), Expect = e-110
 Identities = 256/609 (42%), Positives = 291/609 (47%), Gaps = 106/609 (17%)

Query: 265  ETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG 324
            E G+  +P LP PP    P L G      S+ E+ E        G   +PG      + G
Sbjct: 939  EKGSKGEPGLPGPPGPMDPNLLG------SKGEKGEP-------GLPGIPGVSGPKGYQG 985

Query: 325  SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQ 383
                PG    + GL GQ G PG PGP G  G PG P L GPPGL   +  +G  GP  ++
Sbjct: 986  LPGDPG----QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041

Query: 384  TVPGPQGPPGPPGRDGTPGRDGEPGDPGED-----GKPGDTGPQGFPGTPGDVGPKGDKG 438
              PGP G PG PG  G PG+ G+ GDPG       G PG  G  G PG PG+ G KG  G
Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101

Query: 439  DPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491
            DPG+       G +G PG  G PG PGP                         GP+G  G
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPP------------------------GPKGISG 1137

Query: 492  PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP--GREGPP 549
            PPG PG+PG PG  G  G      PGP G  G PG++G PG  G  G PG P  G  GPP
Sbjct: 1138 PPGNPGLPGEPGPVG--GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195

Query: 550  GRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPA 609
            G  G  G  G+ G PG  G+ G PGP   +GE G  G PG  GPPGPPG PGP       
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSPGP------- 1245

Query: 610  GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPG 669
              +  +G+ GP     R   GP G  GLPG +G PG+PG  G KGE G  G PG PGLPG
Sbjct: 1246 ALEGPKGNPGPQGPPGR--PGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1303

Query: 670  REGIAGP---QGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSV 725
             +G  GP   QG  G  G  G KGDPG  GV G PG+ GP G PG               
Sbjct: 1304 LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA------------- 1350

Query: 726  PGPEGRPGFAGFPGPAGPKGNLG-SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAK 784
             GPEG PG  G PGP G  G  G S   +G  GP G  G+PG              KG  
Sbjct: 1351 -GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG-------------LKGLP 1396

Query: 785  GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 844
            G  G +G PGP G PG  G  G PG  G  G  G  G  G+PG      G+ G PGP G 
Sbjct: 1397 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR----GLDGPPGPDGL 1452

Query: 845  PGPPGPPGT 853
             GPPGPPGT
Sbjct: 1453 QGPPGPPGT 1461



 Score =  386 bits (992), Expect = e-107
 Identities = 260/666 (39%), Positives = 299/666 (44%), Gaps = 151/666 (22%)

Query: 500  GLPGEPGR-FGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558
            G P E    +G +       +G+ G  G  G PG  G PG PG PG EGPPG  GQKG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 559  GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618
            G  G PG KG +G PG  G  G  GL G PG  G PGP G PG  G     GF    G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 619  GPFWSTARSADGPQGPPGLPGLKGDPG---VPGLPGAKGEVGADGVPGFPGLPGREGIAG 675
            G          GP GPPG+PG+KG+PG   +  LPG KG  G  G PG  GLPG  GI G
Sbjct: 141  G--------LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 676  PQGPKGDRGSRGEKGDPGKDG---------------VGQPGLPGPPGPPGPV-------- 712
            P GP G  G  G  G PG  G                G+ GL GPPGPPG +        
Sbjct: 193  PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 713  VYVSEQDGSVLSVPGPEGRPGFAGFPGP----AGPKGNLGSKGERGSPGPKGEKGEPGSI 768
            V   + D  +    GP G PG  G PGP     G KG  G  G+RG PG  GE G+PG  
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 769  FSP-DGGALG-PAQKGAKGEPGFRGPPGP----------------------YGRPGYKGE 804
              P D G  G P + G KG+ G  GPPGP                       G PG KGE
Sbjct: 313  GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 805  IGFP-----------------GRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPG 843
             GFP                 G PG PG  G +G+KG+ G   +      G+ G PG PG
Sbjct: 373  RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPG 432

Query: 844  PPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE-------------VGP 890
             PGPPGP G  +  S+   E   PGPPG PG++G  G +G KG+              GP
Sbjct: 433  LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 891  PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER------GEPGGGGFFGS--------- 935
            PG PG              G+KG++G AG  G +      G PG  GF GS         
Sbjct: 493  PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 936  -----------------SLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPG 974
                              LPG PG PG  G PG+PGPKGE    + +G+ GPPG  G PG
Sbjct: 553  FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 975  I-GYEGRQGPP--GPPGP------------PGPPSFPGPH---RQTISVPGPPGPPGPPG 1016
            + G  G  GPP  GPPGP            PG P  PGP     QTI+ PG PG PG PG
Sbjct: 613  LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG 672

Query: 1017 PPGTMG 1022
              G +G
Sbjct: 673  RDGDVG 678



 Score =  243 bits (621), Expect = 7e-64
 Identities = 158/371 (42%), Positives = 183/371 (49%), Gaps = 63/371 (16%)

Query: 681  GDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGP 740
            G +G +GE+G PG +G   PGLPG PGP GP              PGP G+ G  G PGP
Sbjct: 42   GIKGEKGERGFPGLEG--HPGLPGFPGPEGP--------------PGPRGQKGDDGIPGP 85

Query: 741  AGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG 800
             GPKG  G  G  G PG  G  G PG   +P    + P   G KGE GF G PG  G  G
Sbjct: 86   PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI-PGCNGTKGERGFPGSPGFPGLQG 144

Query: 801  YKGEIGFPGRPGRPG---MNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857
              G  G PG  G PG   M+ L G KG PG      G++G+PGP G PGP GPPG P   
Sbjct: 145  PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP-GIQGLPGPTGIPGPIGPPGPP--- 200

Query: 858  SNVFAESSRPGPPGLPGN--------QGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMK 909
                     PGPPGLPG         QGP G KG +G  GPPGPPGQ       ++ E  
Sbjct: 201  ----GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF- 255

Query: 910  GEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPG 968
                      QKG++G PG  G        PPGPPG RG PG PG  KGE  +G+ G PG
Sbjct: 256  ----------QKGDQGLPGDRG--------PPGPPGIRGPPGPPGGEKGE--KGEQGEPG 295

Query: 969  PQGPPGIGYEGRQGPPGPPGPPGPPSFPG-PHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
             +G PG   +G  G PG PG PG P +PG P R      G  G  GPPGPPG +    G 
Sbjct: 296  KRGKPG--KDGENGQPGIPGLPGDPGYPGEPGRD--GEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 1028 RLWATRQAMLG 1038
             +    +  +G
Sbjct: 352  GITIGEKGNIG 362



 Score =  157 bits (398), Expect = 5e-38
 Identities = 119/323 (36%), Positives = 142/323 (43%), Gaps = 43/323 (13%)

Query: 817  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876
            +G+KGEKGE G   L  G  G+PG PGP GPPGP G          +   PGPPG  G +
Sbjct: 41   SGIKGEKGERGFPGLE-GHPGLPGFPGPEGPPGPRGQK-------GDDGIPGPPGPKGIR 92

Query: 877  GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936
            GPPG  G  G  G PG PG              G +G  G  G KGERG PG  GF    
Sbjct: 93   GPPGLPGFPGTPGLPGMPGH---------DGAPGPQGIPGCNGTKGERGFPGSPGF---- 139

Query: 937  LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFP 996
             PG  GPPGP G PG+ G  G  I      PGP+G PG       GPPG  G PGP   P
Sbjct: 140  -PGLQGPPGPPGIPGMKGEPGSIIMSSL--PGPKGNPGY-----PGPPGIQGLPGPTGIP 191

Query: 997  GPHRQTISVPGPPGPPGPPGPPGTMG--ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQ 1054
            GP    I  PGPPG  GPPGPPG  G   + G+     +     Q  + P G    ++EQ
Sbjct: 192  GP----IGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247

Query: 1055 EE-LYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1113
            +  + V  Q G      +   P  RG         PP     +      +  P    +P 
Sbjct: 248  KRPIDVEFQKG------DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301

Query: 1114 R-ADDILASPPRLPEPQPYPGAP 1135
            +  ++     P LP    YPG P
Sbjct: 302  KDGENGQPGIPGLPGDPGYPGEP 324


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  536 bits (1381), Expect = e-152
 Identities = 362/868 (41%), Positives = 411/868 (47%), Gaps = 153/868 (17%)

Query: 275  PAPPPVTTPPLAG----GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG 330
            P PPP   PP  G    G     + S    E+  +   G   LPG        G V  PG
Sbjct: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511

Query: 331  GRVKEG---------GLKGQKGEPGVPGPPGRAGPPGSPCLPGP---PGLPCPVSPLGPA 378
             + ++G         G KG+KG  G+PGPPGR G  G    PG    PGLP  V   GP 
Sbjct: 512  PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQ 571

Query: 379  GPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE------DGKPGDTGPQGFPGTPGDVG 432
            GP    +PGP G  G PG  G  G  G  G+ GE       GKPGDTG QG PG  G  G
Sbjct: 572  GPP--GLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG 629

Query: 433  PKGDKGD------PGV-----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSG 475
            P+G+KGD      PGV           GE+G PGP+G  G PGP         I  EG  
Sbjct: 630  PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGP---IGPEGRD 686

Query: 476  FGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPG 535
                L+ LRG +G  GPPG PG+ GL G PG  GV     PGP G PG+PG  G PG PG
Sbjct: 687  GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP--PGPGGSPGLPGEIGFPGKPG 744

Query: 536  LPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPG 595
             PGP GPPG++GP G  G  G+ GE G  G  G  G PG  G  GE GLAG PG  G  G
Sbjct: 745  PPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804

Query: 596  PPGPPGPPGPGLPAGFDDMEGS-GGPFWSTARSAD---GPQGPPGLPGLKG----DPGVP 647
             PG PG PG     G    +G  G P     R      GP GPPGLPG        P +P
Sbjct: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 864

Query: 648  GLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPP 706
            G  G KGE G  G+PG PGL GR G  GPQGP G  G++G++G  G  G  G PG PG  
Sbjct: 865  GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV 924

Query: 707  GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766
            G PGP              PG  G PG  G PG  G +G  G+ GE GSPGP G +G+PG
Sbjct: 925  GAPGP-----------SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 973

Query: 767  SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPG--------------------YKGEIG 806
            +      G  GP  KG  GEPG RG PG  G  G                     KG+ G
Sbjct: 974  A-----PGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRG 1028

Query: 807  FPGRPGRPGM--------------NGLKGEKGEPGDASL-GF-------GMRGMPGPPGP 844
             PG PG PG               +G  G+KG PG   L GF       G  G PG PG 
Sbjct: 1029 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGE 1088

Query: 845  PGPPGPPGTPVY----DSNVFAE----SSRPGPPGL------------PGNQGPPGPKGA 884
             GPPG PG        D N+ A+       PGPPGL            PG  G  G +G 
Sbjct: 1089 RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGK 1148

Query: 885  KGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP 944
            KGE GPPG PG      +      +GE+G  G+ GQKG++G PG  GF G   PG PGPP
Sbjct: 1149 KGEAGPPGLPGP---PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGP--PGNPGPP 1203

Query: 945  GPRGYPGIPGPKG-ESIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPPSFP 996
            G  G  G  GP G +   G+ GPPGPQGP G+       G EGR G PGPPG PG    P
Sbjct: 1204 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263

Query: 997  GPHRQTISVPGPPGPPGPPGPPGTMGAS 1024
            G       +PGP G  GPPG  G  G S
Sbjct: 1264 G-------LPGPEGARGPPGFKGHTGDS 1284



 Score =  510 bits (1313), Expect = e-144
 Identities = 334/818 (40%), Positives = 384/818 (46%), Gaps = 151/818 (18%)

Query: 301  EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 360
            E+      G   LPG+ S+ T     R PG    E G KG+KG+PG+PG PG  G PG  
Sbjct: 838  EKGEAGPAGPPGLPGTTSLFT--PHPRMPG----EQGPKGEKGDPGLPGEPGLQGRPGEL 891

Query: 361  CLPGPPGLP----------CPVSPLGPAGPALQTVPGPQGPPGP---PGRDGTPGRDGEP 407
               GP G P           P +   P  P     PGP GPPG    PG  GTPG+DGE 
Sbjct: 892  GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGER 951

Query: 408  GDPG---EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHD 464
            G+ G   E+G PG  GP+G PG PG  GP      PG G+ G PG +G PG PGP     
Sbjct: 952  GEKGAAGEEGSPGPVGPRGDPGAPGLPGP------PGKGKDGEPGLRGSPGLPGPLGTKA 1005

Query: 465  KLTFI-DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPG 523
                +   E    GG  + ++G RG PG PG PG  G PG      +  +  PGP+G PG
Sbjct: 1006 ACGKVRGSENCALGG--QCVKGDRGAPGIPGSPGSRGDPG------IGVAGPPGPSGPPG 1057

Query: 524  VPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA-------------------- 563
              G  G  G PG PGP GP GR+G PG  G++G  G+ G                     
Sbjct: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117

Query: 564  ----------PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 613
                      PG KG KG PG  G  G  G  G  GP G PGPPG  GP G     G D 
Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177

Query: 614  MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGI 673
              G             G QG PG+PG  G PG PG PGA G  GA G PG  G PG+EG 
Sbjct: 1178 EVGQ-----------KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226

Query: 674  AGPQGPKGDRGSRGEKGDPGKDG----------VGQPGLPGPPGPPGPVVYVSEQDGSVL 723
             GPQGP G  G  GE+G  G+DG           G+PGLPGP G  GP  +      S  
Sbjct: 1227 PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS-- 1284

Query: 724  SVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPD-----GGALGP 778
              PGP G  G  G PG  G  G  G  G  G  GP+G +G PG   SP      G +  P
Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 1344

Query: 779  AQKGAKGE------PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG 832
             QKG+KGE      PGF GP GP G PG KG  G  G PG+PG  G KGE+G+PG     
Sbjct: 1345 GQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPG----- 1399

Query: 833  FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPG 892
              ++G  GPPG  G PG PG P +  +    +   GP GLPG  GP GP G  G+ G PG
Sbjct: 1400 --IKGDKGPPGGKGQPGDPGIPGHKGH----TGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453

Query: 893  PPGQFP-FDFL----------QLE------------AEMKGEKGDRGDAGQKGERGEPGG 929
              G+ P  + L          QLE            A MK  +G  G  G  G+ G PG 
Sbjct: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513

Query: 930  GGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGP 989
             G  G   PG PG  G  G  G  GPKGE  RG  G PG    PG+G  G  GPPG PG 
Sbjct: 1514 AGPMGE--PGRPGQGGLEGPSGPIGPKGE--RGAKGDPGA---PGVGLRGEMGPPGIPGQ 1566

Query: 990  PGPPSF--------PGPHRQTISVPGPPGPPGPPGPPG 1019
            PG P +        PGP  +T    G PG PGPPGPPG
Sbjct: 1567 PGEPGYAKDGLPGIPGPQGET-GPAGHPGLPGPPGPPG 1603



 Score =  501 bits (1290), Expect = e-141
 Identities = 333/822 (40%), Positives = 383/822 (46%), Gaps = 129/822 (15%)

Query: 337  GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 396
            GL+G  G PGVPGPPG  G PG P   G PG P P  P GP G       GP GPPGPPG
Sbjct: 711  GLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK-----DGPNGPPGPPG 765

Query: 397  RDGTPGRDGEPGDPGEDG------------KPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 442
              G PG  GE G PG+ G            +PG+ G  G PG PG  G +G+KGD G   
Sbjct: 766  TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825

Query: 443  -----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491
                       GE+G  GP GPPG PG        T +        G+    +GP+G  G
Sbjct: 826  ELGLPGLKGDRGEKGEAGPAGPPGLPGT-------TSLFTPHPRMPGE----QGPKGEKG 874

Query: 492  PPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPGVPGREGPPGFPGLPGPPGPPG 544
             PG PG PGL G PG  G      P       G  G PG  G  G PG  G PGP GPPG
Sbjct: 875  DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG 934

Query: 545  REGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGP-----PGPPGP 599
              G PG  G  G  GE G  G  G +G+PGP G RG+ G  G PGP G      PG  G 
Sbjct: 935  SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS 994

Query: 600  PGPPGP-GLPAGFDDMEGS-----GGPFWSTARSADGPQGPPGLPGLKGDPG--VPGLPG 651
            PG PGP G  A    + GS     GG      +   G  G PG PG +GDPG  V G PG
Sbjct: 995  PGLPGPLGTKAACGKVRGSENCALGG---QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPG 1051

Query: 652  AKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPG------- 704
              G  G  G PG  GLPG  G  GP G  G  G+ GE+G PGK G+     PG       
Sbjct: 1052 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAK 1111

Query: 705  ------PPGPPG-PVVYVSEQDGSVLSVPGPEGR---------PGFAGFPGPAGPKGNLG 748
                  PPGPPG P +   + D  V   PG EG          PG  G PG AGP+G+ G
Sbjct: 1112 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171

Query: 749  SKGERGSPGPKGEKGEPG--SIFSPDGGALGPAQKG---AKGEPGFRGPPGPYGRPGYKG 803
             +G  G  G KG++G PG      P G    P   G   A G PG +G PG  G PG +G
Sbjct: 1172 ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQG 1231

Query: 804  EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863
              G PG PG  G  G  G+ G PG+     G  G PG PGP G  GPPG   +  +  A 
Sbjct: 1232 PSGLPGIPGEEGKEGRDGKPGPPGEP----GKAGEPGLPGPEGARGPPGFKGHTGDSGAP 1287

Query: 864  SSR--------PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR 915
              R        PG  GLPG  G  GP G +G  GP GPPG+             GE G  
Sbjct: 1288 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK------NGSPGSPGEPGPS 1341

Query: 916  GDAGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG 974
            G  GQKG +GE G  G  G   P GPPG PG +G PG  G  G+   G+PG  G +G PG
Sbjct: 1342 GTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP--GEPGFKGERGDPG 1399

Query: 975  IGYEGRQGPPGPPGPPGPPSFPGPHRQT-----ISVPG------PPGPPGPPGPPGTMGA 1023
            I  +G +GPPG  G PG P  PG    T       +PG      PPGPPG PG PG  G 
Sbjct: 1400 I--KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457

Query: 1024 SSGVR-LWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNG 1064
            S  +  L    Q  LG+  E    +L+  A+    Y++   G
Sbjct: 1458 SPSMETLRRLIQEELGKQLETRLAYLL--AQMPPAYMKSSQG 1497



 Score =  470 bits (1209), Expect = e-132
 Identities = 335/848 (39%), Positives = 382/848 (45%), Gaps = 161/848 (18%)

Query: 239  EEGDDSDGASGDSG-SGL-GDARELLREETGAALKPRLPAPPPVTTP-PLAGGSSTEDSR 295
            E+GD   G  G+ G  GL GD  E  + E G A  P LP    + TP P   G   E   
Sbjct: 817  EKGDQ--GEKGELGLPGLKGDRGE--KGEAGPAGPPGLPGTTSLFTPHPRMPG---EQGP 869

Query: 296  SEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPG---P 350
              E  +       G Q  PG        G    PG + +EG  G  G  G PG PG    
Sbjct: 870  KGEKGDPGLPGEPGLQGRPGELGPQ---GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 926

Query: 351  PGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPG-----RD 404
            PG +GPPGS   PG  G P      G  G A +   PGP GP G PG  G PG     +D
Sbjct: 927  PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 986

Query: 405  GEPGDPGEDGKPGDTGPQ--------------------GFPGTPGDVGPKGDKGDPGVGE 444
            GEPG  G  G PG  G +                    G  G PG  G  G +GDPG+G 
Sbjct: 987  GEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGV 1046

Query: 445  RGPPGPQGPPGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPG--------- 491
             GPPGP GPPG  G         F   +G     G  G+    RGP G PG         
Sbjct: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN-PGERGPPGKPGLSSLLSPGD 1105

Query: 492  ------------PPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG- 538
                        PPGPPG+PGLPG  G  GV     PG  G  G  G  GPPG PG PG 
Sbjct: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK--PGREGTEGKKGEAGPPGLPGPPGI 1163

Query: 539  --PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 596
              P G  G  G  G  GQKG  G  G PG  G  G PGP GA G +G AG PG  G PG 
Sbjct: 1164 AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGK 1223

Query: 597  PGPPGPPGP-GLPA-----GFDDMEGSGGPFWSTARSAD----GPQGPPGLPGLKGDPGV 646
             GPPGP GP GLP      G +  +G  GP     ++ +    GP+G  G PG KG  G 
Sbjct: 1224 EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGD 1283

Query: 647  PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGP 705
             G PG +GE GA G+PG  GLPG++G  GP GP+G +G RG    PGK+G  G PG PGP
Sbjct: 1284 SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP---PGKNGSPGSPGEPGP 1340

Query: 706  PGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKG---------ERGSP 756
             G PG       Q GS     G  G PG  GF GP GP G  G KG         + G P
Sbjct: 1341 SGTPG-------QKGS----KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP 1389

Query: 757  GPKGEKGEPG--SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRP 814
            G KGE+G+PG      P GG   P   G  G  G  G  GP G PG  G +G PG PG+P
Sbjct: 1390 GFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQP 1449

Query: 815  GMNGLKGEK--------------GEPGDASLGFGMRGMP--------GPPGPPGPPGPPG 852
            G  GL+GE               G+  +  L + +  MP        G PGPPGPPG  G
Sbjct: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509

Query: 853  TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912
             P   +    E  RPG  GL G  GP GPKG +G  G PG PG                 
Sbjct: 1510 LPGR-AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV---------------- 1552

Query: 913  GDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPG---PRGYPGIPGPKGESIRGQPGPPGP 969
            G RG+ G  G  G+PG  G+    LPG PGP G   P G+PG+PGP        PGPPG 
Sbjct: 1553 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGP--------PGPPGQ 1604

Query: 970  QGPPGIGY 977
              P    Y
Sbjct: 1605 CDPSQCAY 1612



 Score =  249 bits (635), Expect = 2e-65
 Identities = 181/534 (33%), Positives = 219/534 (41%), Gaps = 139/534 (26%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTT- 304
            G  GD G      RE    + G A  P LP PP +  P  + G    D    +  +Q   
Sbjct: 1129 GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP 1188

Query: 305  -----VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAG-- 355
                 +   G    PG+D ++   G     G   KEG  G +G  G PG+PG  G+ G  
Sbjct: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 1248

Query: 356  ----PPGSPCLPGPPGLPCPVSPLGPAG----------------------PALQTVPG-- 387
                PPG P   G PGLP P    GP G                      P  + +PG  
Sbjct: 1249 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308

Query: 388  ----------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 437
                      PQGP GPPG++G+PG  GEPG  G  G+ G  G  G PG PG +GP+G  
Sbjct: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 1368

Query: 438  GDPGVGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPP 496
            G+PG  E+G PG +G PG PG P F+ ++            GD   ++G +G PG  G P
Sbjct: 1369 GEPG--EKGVPGKEGVPGKPGEPGFKGER------------GD-PGIKGDKGPPGGKGQP 1413

Query: 497  GVPGLPGEPGRFGV-NSSDVPGPAGLPGVPGREGPPGFPGL------------------- 536
            G PG+PG  G  G+     +PG  G  G PG  G PGFPGL                   
Sbjct: 1414 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELG 1473

Query: 537  -------------------------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 571
                                     PGPPGPPG++G PGR G  G  G  G  G +G  G
Sbjct: 1474 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 1533

Query: 572  APGPAGARGESGLAGAPGPA-----GPPGPPGPPGPPG---PGLPAGFDDMEGSGGPFWS 623
              GP G RG  G  GAPG       GPPG PG PG PG    GLP               
Sbjct: 1534 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP--------------- 1578

Query: 624  TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG-IAGP 676
                  G  GP G  G  G PG+PG PG  G+        F  L  R G + GP
Sbjct: 1579 ------GIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626



 Score =  131 bits (330), Expect = 4e-30
 Identities = 100/259 (38%), Positives = 119/259 (45%), Gaps = 50/259 (19%)

Query: 777  GPAQKGAKGEPGFRGPPGPYGRPGYKG--EIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 834
            GP Q     EP    PP P  RP   G  +IGF         +   GEKGE G A    G
Sbjct: 441  GPCQVTVVTEPP---PPPPPQRPPTPGSEQIGFLKTIN---CSCPAGEKGEMGVA----G 490

Query: 835  MRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG----PPGPKGAKGEVGP 890
              G+PGP G  G  GP G P             GP G  G+ G      G KG KG +G 
Sbjct: 491  PMGLPGPKGDIGAIGPVGAP-------------GPKGEKGDVGIGPFGQGEKGEKGSLGL 537

Query: 891  PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP 950
            PGPPG+             G KG RG+ G+ GE G PG  G  G    GPPG PGP G  
Sbjct: 538  PGPPGR------------DGSKGMRGEPGELGEPGLPGEVGMRGPQ--GPPGLPGPPGRV 583

Query: 951  GIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPP 1009
            G PG +GE  RG+ G  G +G  G+ G+ G+ G  G  G PGP    GP  +     G  
Sbjct: 584  GAPGLQGE--RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEK----GDV 637

Query: 1010 GPPGPPGPPGTMGASSGVR 1028
            GP GPPG PG++    G++
Sbjct: 638  GPAGPPGVPGSVVQQEGLK 656


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  533 bits (1374), Expect = e-151
 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%)

Query: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300
            G  S GA G+SG            + G      +  PP  T  P   G    D       
Sbjct: 557  GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 604

Query: 301  EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 352
            E       G   LPG   D     +   + P G   + G++G+ GE      PG  GP G
Sbjct: 605  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 664

Query: 353  RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412
              GP G+P  PG PG+     P GP G       GPQG PGPPG+ G PG  G PG  G 
Sbjct: 665  LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 719

Query: 413  DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 465
             G PG+ GPQG PG  G  G  G  G PG        G  GPPGPQGP G PGP      
Sbjct: 720  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 779

Query: 466  LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 507
                 ++GS          GF GD+            GPRG  GP GP G  G  G+PG 
Sbjct: 780  DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839

Query: 508  FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 551
             G        G  GLPG PGR+GP      PGFPG         + G PGP G+ GP G 
Sbjct: 840  SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 899

Query: 552  TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 607
             G +G+ G  G PG KG+ G  GP G  GE G  G  GP G PGP GPPGPPG    PG 
Sbjct: 900  RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 959

Query: 608  PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 659
            P      GF    G  GP         GPQGP G  G    +G PG PG PG +G  GA 
Sbjct: 960  PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014

Query: 660  GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 718
            G  G  G PG +GI+G  GP G RG  GE+G PG  G  G  G  GP GPPGPV    E+
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074

Query: 719  DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 765
              +  + P G  GRPG  G PGPAG KG  G KG +G             PGP G  G P
Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1134

Query: 766  GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824
            G     D G +G P QKG+KG+ G  GPPGP G  G  G  G  G  G PG  G +G  G
Sbjct: 1135 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1192

Query: 825  EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 881
            + GD     G RG PGPPGP    G PGPPG    + +V       GPPG PG +GP GP
Sbjct: 1193 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1244

Query: 882  KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 934
             GA G  GPPG  G              GEKG+ G+AG  G  GE G GG  G       
Sbjct: 1245 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1295

Query: 935  SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 986
            +  PG  GPPG +G PG  GPKG        G PGPPG  GP G     G +G  G PG 
Sbjct: 1296 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1355

Query: 987  PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1043
            PGPPGP              GPPGPPG  GPPG  GA         RQ   G   E    
Sbjct: 1356 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1398

Query: 1044 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1099
             P G    V  Q         G R +     E   P   G D     + PP +     +P
Sbjct: 1399 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1458

Query: 1100 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1150
              + E  HP          L  PP          LP  Q  PGA          PA P  
Sbjct: 1459 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1510

Query: 1151 PP 1152
            PP
Sbjct: 1511 PP 1512



 Score =  528 bits (1359), Expect = e-149
 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%)

Query: 305  VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 364
            V  +G +   G +      G    PG    + G KG+ G PG+PG PGR GP GS   PG
Sbjct: 813  VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 871

Query: 365  PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412
             PG             P P    GP GP  +   G +GP G PG  GT G DG PG PGE
Sbjct: 872  FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 929

Query: 413  DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471
             G  G  GP GFPG  G  GP G  G PG  G+RG  G QG  GPPGP         +  
Sbjct: 930  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 983

Query: 472  EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 523
            +G +G  G +    G RG PGPPGPPG  GLPG  G+ G      P       GPAGL G
Sbjct: 984  QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1039

Query: 524  VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577
             PG  G PG  G PG      P GPPG  G PG  G  G+ G  G PG  G +G PGPAG
Sbjct: 1040 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1099

Query: 578  ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 633
             +G  G  G  GPAG  G  GP G PGP  PAG    +G  G    P    ++   G  G
Sbjct: 1100 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159

Query: 634  PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 693
            PPG PGL+G  G PG+ G  GE G  G  G  G  G EG  G  GP G  G +G  G PG
Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219

Query: 694  KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 745
            + G    VG  G PGPPGP GP       +G+     GP+G PG  G  G  G KG    
Sbjct: 1220 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1271

Query: 746  --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803
              N G  GE G  GPKGE+GE G    P  GA GP   GAKG PG  GP G  G  G+ G
Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1327

Query: 804  EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863
            + G PG PG  G +G+ G+KGE GD        G PGPPGP G  GPPG P         
Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1371

Query: 864  SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 923
              + GPPG  G +G  G KGAKGE G  GPPG+      Q  A   G +G RG  G  GE
Sbjct: 1372 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1430

Query: 924  RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 967
            +G PG  G  G   PGP GPPG  G  G PG KGE                  +G  G P
Sbjct: 1431 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488

Query: 968  GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1015
            G QG PG  G  G  GP GP GPPGPP  PGP   +      GP         PGPPG P
Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1548

Query: 1016 GPPG 1019
            GPPG
Sbjct: 1549 GPPG 1552



 Score =  496 bits (1277), Expect = e-140
 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%)

Query: 329  PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 378
            P G     G  G +G  G PG PG  GPPG P LPG  GLP P   +          G  
Sbjct: 458  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517

Query: 379  GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 407
            GP                  AL+  PGP       GP G PG  G  G  G+P       
Sbjct: 518  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 577

Query: 408  --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 455
                    G PG+ G+PG  G +G PG PG  G +G  G PG+    G RG  GPQGPPG
Sbjct: 578  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 637

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
            PPG      +   I   G         L GPRG PG PG PG+ G+ G PG  G      
Sbjct: 638  PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 692

Query: 516  PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575
             GP G PG PG++G PG  GLPGP GP    GPPG  G +G  G AG PG  G  G PG 
Sbjct: 693  MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 749

Query: 576  AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 617
             G  GE G  G PGP GP G PGP G  G                 G P    DM  +G 
Sbjct: 750  EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 809

Query: 618  GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 661
             G       R  DGP+GP G  G  GD               PG+PG PG +G  G+ G 
Sbjct: 810  RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869

Query: 662  PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 702
            PGFPG             PG  G  GP GP+G RG+RG  G PG  G        G PG 
Sbjct: 870  PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 929

Query: 703  PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754
             GP GP GPV +           +DG +   PG  G  GF G  GP GP G +G +G  G
Sbjct: 930  RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 988

Query: 755  SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 809
              GP GE+G PG    P + G  G A K GAKG+P   G  G  GP G  G+ GE G PG
Sbjct: 989  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1048

Query: 810  RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861
              G PG+ G +G +G PG         S G  G  G+PG PGP GPPGP G         
Sbjct: 1049 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1099

Query: 862  AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921
                  G PG  G QGP G  G +G VG PGP G          A   GE GD+G+ G+ 
Sbjct: 1100 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1146

Query: 922  GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 965
            G++G  G  G  G   PGPPG  GP G PGI      PGP+G          E  RG PG
Sbjct: 1147 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204

Query: 966  PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1021
            PPGP   QG PG  G +G  G  GP GPPGPP   GP        GP G  GP GPPG++
Sbjct: 1205 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1257

Query: 1022 GASSGV 1027
            G+  GV
Sbjct: 1258 GSVGGV 1263



 Score =  436 bits (1121), Expect = e-122
 Identities = 333/880 (37%), Positives = 384/880 (43%), Gaps = 166/880 (18%)

Query: 391  PPGPPGRDGTPGRDGEPG----DPGEDGKPGDTGPQGFPGT--PGDV--GPKGDKGDPGV 442
            P  PP  +  PG   E           G  G+ G +G P    PG +  GP G  G  G+
Sbjct: 405  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464

Query: 443  GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 502
               GPPG QGP GPPG                          G RG PG PG PG  GLP
Sbjct: 465  --MGPPGLQGPTGPPGDP------------------------GDRGPPGRPGLPGADGLP 498

Query: 503  GEPG-------RFGVNSSDVP---------------------GPAGLPGVPGREGPPGFP 534
            G PG       R+G + S  P                     GP G  G+ GR GP G P
Sbjct: 499  GPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP 558

Query: 535  GL---------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLA 585
            G          PGP GP G +GPPG TG+ G  G  GA G +G  G PG  G RG  GL 
Sbjct: 559  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP 618

Query: 586  GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG-------PFWSTARSADGPQGPPGLP 638
            G PG  G  G  GP GPPG   P G D M G  G       P  +  R   GP+G PG P
Sbjct: 619  GLPGDKGHRGERGPQGPPG---PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 675

Query: 639  GLKGDPGVPGLPGAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGKD 695
            G  G  GV G PG KG +G  G PG PG    PG +G+ GPQGP G  G +G +G PG  
Sbjct: 676  GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 735

Query: 696  GVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGS 755
            G+  PG  GPPG PG      E+    L  PGP+G     G+PGP G KG  G +G +GS
Sbjct: 736  GL--PGADGPPGHPGKEGQSGEK--GALGPPGPQGP---IGYPGPRGVKGADGVRGLKGS 788

Query: 756  PGPKGEKGEPGSIFSPDGGALGP----AQKGAKGEPGFRGP---------PGPYGRPGYK 802
             G KGE G PG  F  D G  G      Q G +GE G  GP         PGP G+ G K
Sbjct: 789  KGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 846

Query: 803  GEIGFPGRPGRPGMNGLKGEKGEPG--DASLGFGMRGMPGPPGPPGPPGPPGT------- 853
            G++G PG PG PG  G KG  G PG   A+   G RG+ G PGP G  GP G        
Sbjct: 847  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 906

Query: 854  -PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912
             P         S   GPPG PG +GP GP+G  G  GP GPPG    D L       G  
Sbjct: 907  GPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL------PGHP 960

Query: 913  GDRGDAGQKGERGEPGGGGFFG-------------SSLPGPPGPPGPRGYPGI------- 952
            G RG+ G +G+ G PG GG  G                PGPPGPPG +G PG        
Sbjct: 961  GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 1020

Query: 953  --PGPKGES-------IRGQPGP---PGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH 999
              PGP+G S       +RG PG    PG QG PG+ G EG QGPPGP G PG     G  
Sbjct: 1021 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT- 1079

Query: 1000 RQTISVPGPPGPPGPPGPPGTMGA--SSGVRLWATRQAMLGQV----HEVPEGWLIFVAE 1053
               I +PG PGP GPPGP G  GA    G +  A R  + G V       P G      +
Sbjct: 1080 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1139

Query: 1054 QEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPW 1113
            + E+    Q G +  + E   P P G    V A   P +   D  P PR +      +  
Sbjct: 1140 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA---PGIAGGDGEPGPRGQQGMFGQKGD 1196

Query: 1114 RADDILASPPRLPEPQPYPGAP-HHSSYVHLRPARPTSPP 1152
                    PP     Q  PG P        + P  P  PP
Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1236



 Score =  362 bits (929), Expect = 1e-99
 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%)

Query: 309  GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 360
            GA+  PG   +S  DG       PG R   G     GLKG +G  G PGP G  G  GS 
Sbjct: 1018 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1077

Query: 361  CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419
               GP GLP    P GP GPA +   PG +GP GP GRDG  G  G PG  G  G PG+ 
Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1137

Query: 420  GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 478
            G +G  G PG  G KGDKG+ G    GPPG QGP G PG +    +      +G  G  G
Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1195

Query: 479  DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 538
            D     G RGFPGPPGP G+ GLPG PG  G N  DV GP G PG PG  GP G  G  G
Sbjct: 1196 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1249

Query: 539  PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 598
            P GPPG  G  G  G+KG  GEAG PG  G  G  GP G RGE G AG PG AGPPG  G
Sbjct: 1250 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1309

Query: 599  PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 636
            PPG                  PPG   PAG D + G     G P         G  GPPG
Sbjct: 1310 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1369

Query: 637  LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 679
             PG +G PG  G  G +GE GA G  G  G PG+ G  GPQGP                 
Sbjct: 1370 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1429

Query: 680  -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 704
                                     KGD GS+GEKG PG  G+          G  GLPG
Sbjct: 1430 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489

Query: 705  PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 758
              G PG     ++ DG +    GP G PG  G PGP GPKGN GS      KG+ G PGP
Sbjct: 1490 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1544

Query: 759  KGEKGEPGSIFSP 771
             G  G PG +  P
Sbjct: 1545 PGSPGPPGEVIQP 1557



 Score =  347 bits (891), Expect = 3e-95
 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%)

Query: 279  PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 330
            PV  P  AG  GS  ED    E+ E     S G +   G        G V  PG      
Sbjct: 1121 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180

Query: 331  --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 385
              G   + G+ GQKG+ G  G PG  GP G   LPGPPG       V P+GP GP     
Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1235

Query: 386  PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 442
            PGP+GP GP G DG    PG  G  G  GE G+PG+ G  G PG  G  GPKG++G+ G 
Sbjct: 1236 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1294

Query: 443  GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 502
             E GPPG  GPPG  GP                 G D     GP+G PGP G PG PG P
Sbjct: 1295 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1332

Query: 503  GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562
            GEPG           PAG  GV G +G  G PG PGPPGP G  GPPG  G++G  G AG
Sbjct: 1333 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1381

Query: 563  APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 622
            A G +G KGA G AGA G  G  G  GP GP G PGP G  G   P G   + G+ G   
Sbjct: 1382 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1438

Query: 623  STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682
                   GP GPPGLPGLKGD      PG+KGE       G PGL G  G  G QG KGD
Sbjct: 1439 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1484

Query: 683  RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741
            RG  G +G PG  G G  PG  GP GPPGP             +PGP+G  G  G  GPA
Sbjct: 1485 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1533

Query: 742  GPKGNLGSKGERGSPGPKGEKGEPGSIFS 770
            G KG+ G  G  GSPGP GE  +P  I S
Sbjct: 1534 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1562



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 45/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)

Query: 67  AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 125
           AY     A      +  FP   F  DFS+LF ++P       L +I +        G++ 
Sbjct: 73  AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126

Query: 126 SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 184
            GV+ G   + L     G         FR      G+W  +A+SV    V + VDC++  
Sbjct: 127 IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186

Query: 185 RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHC 236
             PL RS R +    G  +F  +    D + F+G I +  +  DP+ +  +C
Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC 236


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  533 bits (1374), Expect = e-151
 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%)

Query: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300
            G  S GA G+SG            + G      +  PP  T  P   G    D       
Sbjct: 506  GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 553

Query: 301  EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 352
            E       G   LPG   D     +   + P G   + G++G+ GE      PG  GP G
Sbjct: 554  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 613

Query: 353  RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412
              GP G+P  PG PG+     P GP G       GPQG PGPPG+ G PG  G PG  G 
Sbjct: 614  LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 668

Query: 413  DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 465
             G PG+ GPQG PG  G  G  G  G PG        G  GPPGPQGP G PGP      
Sbjct: 669  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728

Query: 466  LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 507
                 ++GS          GF GD+            GPRG  GP GP G  G  G+PG 
Sbjct: 729  DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788

Query: 508  FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 551
             G        G  GLPG PGR+GP      PGFPG         + G PGP G+ GP G 
Sbjct: 789  SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 848

Query: 552  TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 607
             G +G+ G  G PG KG+ G  GP G  GE G  G  GP G PGP GPPGPPG    PG 
Sbjct: 849  RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 908

Query: 608  PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 659
            P      GF    G  GP         GPQGP G  G    +G PG PG PG +G  GA 
Sbjct: 909  PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963

Query: 660  GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 718
            G  G  G PG +GI+G  GP G RG  GE+G PG  G  G  G  GP GPPGPV    E+
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023

Query: 719  DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 765
              +  + P G  GRPG  G PGPAG KG  G KG +G             PGP G  G P
Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1083

Query: 766  GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824
            G     D G +G P QKG+KG+ G  GPPGP G  G  G  G  G  G PG  G +G  G
Sbjct: 1084 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1141

Query: 825  EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 881
            + GD     G RG PGPPGP    G PGPPG    + +V       GPPG PG +GP GP
Sbjct: 1142 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1193

Query: 882  KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 934
             GA G  GPPG  G              GEKG+ G+AG  G  GE G GG  G       
Sbjct: 1194 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1244

Query: 935  SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 986
            +  PG  GPPG +G PG  GPKG        G PGPPG  GP G     G +G  G PG 
Sbjct: 1245 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304

Query: 987  PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1043
            PGPPGP              GPPGPPG  GPPG  GA         RQ   G   E    
Sbjct: 1305 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1347

Query: 1044 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1099
             P G    V  Q         G R +     E   P   G D     + PP +     +P
Sbjct: 1348 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1407

Query: 1100 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1150
              + E  HP          L  PP          LP  Q  PGA          PA P  
Sbjct: 1408 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1459

Query: 1151 PP 1152
            PP
Sbjct: 1460 PP 1461



 Score =  528 bits (1359), Expect = e-149
 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%)

Query: 305  VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 364
            V  +G +   G +      G    PG    + G KG+ G PG+PG PGR GP GS   PG
Sbjct: 762  VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 820

Query: 365  PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412
             PG             P P    GP GP  +   G +GP G PG  GT G DG PG PGE
Sbjct: 821  FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 878

Query: 413  DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471
             G  G  GP GFPG  G  GP G  G PG  G+RG  G QG  GPPGP         +  
Sbjct: 879  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 932

Query: 472  EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 523
            +G +G  G +    G RG PGPPGPPG  GLPG  G+ G      P       GPAGL G
Sbjct: 933  QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 988

Query: 524  VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577
             PG  G PG  G PG      P GPPG  G PG  G  G+ G  G PG  G +G PGPAG
Sbjct: 989  FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1048

Query: 578  ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 633
             +G  G  G  GPAG  G  GP G PGP  PAG    +G  G    P    ++   G  G
Sbjct: 1049 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108

Query: 634  PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 693
            PPG PGL+G  G PG+ G  GE G  G  G  G  G EG  G  GP G  G +G  G PG
Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168

Query: 694  KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 745
            + G    VG  G PGPPGP GP       +G+     GP+G PG  G  G  G KG    
Sbjct: 1169 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1220

Query: 746  --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803
              N G  GE G  GPKGE+GE G    P  GA GP   GAKG PG  GP G  G  G+ G
Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1276

Query: 804  EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863
            + G PG PG  G +G+ G+KGE GD        G PGPPGP G  GPPG P         
Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1320

Query: 864  SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 923
              + GPPG  G +G  G KGAKGE G  GPPG+      Q  A   G +G RG  G  GE
Sbjct: 1321 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1379

Query: 924  RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 967
            +G PG  G  G   PGP GPPG  G  G PG KGE                  +G  G P
Sbjct: 1380 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437

Query: 968  GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1015
            G QG PG  G  G  GP GP GPPGPP  PGP   +      GP         PGPPG P
Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497

Query: 1016 GPPG 1019
            GPPG
Sbjct: 1498 GPPG 1501



 Score =  496 bits (1277), Expect = e-140
 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%)

Query: 329  PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 378
            P G     G  G +G  G PG PG  GPPG P LPG  GLP P   +          G  
Sbjct: 407  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466

Query: 379  GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 407
            GP                  AL+  PGP       GP G PG  G  G  G+P       
Sbjct: 467  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526

Query: 408  --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 455
                    G PG+ G+PG  G +G PG PG  G +G  G PG+    G RG  GPQGPPG
Sbjct: 527  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
            PPG      +   I   G         L GPRG PG PG PG+ G+ G PG  G      
Sbjct: 587  PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 641

Query: 516  PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575
             GP G PG PG++G PG  GLPGP GP    GPPG  G +G  G AG PG  G  G PG 
Sbjct: 642  MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 698

Query: 576  AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 617
             G  GE G  G PGP GP G PGP G  G                 G P    DM  +G 
Sbjct: 699  EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 758

Query: 618  GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 661
             G       R  DGP+GP G  G  GD               PG+PG PG +G  G+ G 
Sbjct: 759  RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818

Query: 662  PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 702
            PGFPG             PG  G  GP GP+G RG+RG  G PG  G        G PG 
Sbjct: 819  PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 878

Query: 703  PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754
             GP GP GPV +           +DG +   PG  G  GF G  GP GP G +G +G  G
Sbjct: 879  RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 937

Query: 755  SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 809
              GP GE+G PG    P + G  G A K GAKG+P   G  G  GP G  G+ GE G PG
Sbjct: 938  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997

Query: 810  RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861
              G PG+ G +G +G PG         S G  G  G+PG PGP GPPGP G         
Sbjct: 998  AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1048

Query: 862  AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921
                  G PG  G QGP G  G +G VG PGP G          A   GE GD+G+ G+ 
Sbjct: 1049 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1095

Query: 922  GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 965
            G++G  G  G  G   PGPPG  GP G PGI      PGP+G          E  RG PG
Sbjct: 1096 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153

Query: 966  PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1021
            PPGP   QG PG  G +G  G  GP GPPGPP   GP        GP G  GP GPPG++
Sbjct: 1154 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1206

Query: 1022 GASSGV 1027
            G+  GV
Sbjct: 1207 GSVGGV 1212



 Score =  461 bits (1185), Expect = e-129
 Identities = 401/1208 (33%), Positives = 498/1208 (41%), Gaps = 217/1208 (17%)

Query: 67   AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 125
            AY     A      +  FP   F  DFS+LF ++P       L +I +        G++ 
Sbjct: 73   AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126

Query: 126  SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 184
             GV+ G   + L     G         FR      G+W  +A+SV    V + VDC++  
Sbjct: 127  IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186

Query: 185  RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDS 244
              PL RS R +    G  +F  +    D + F+G I +  +  DP+ +  +C +    D 
Sbjct: 187  TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC-EHYSPDC 243

Query: 245  DGASG----------DSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDS 294
            D ++           D  + + D +E      G     +  AP  V+        + E +
Sbjct: 244  DSSAPKAAQAQEPQIDEANIVDDFQEY---NYGTMESYQTEAPRHVS-------GTNEPN 293

Query: 295  RSEEV--EEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG 352
              EE+  EE  T     +Q     D++       +   GR  +  + G  GE        
Sbjct: 294  PVEEIFTEEYLTGEDYDSQRKNSEDTLY----ENKEIDGRDSDLLVDGDLGEYDFYEYKE 349

Query: 353  RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412
                P SP          P    GP  PA   +            + +    G  G+ G+
Sbjct: 350  YEDKPTSP----------PNEEFGPGVPAETDIT-----------ETSINGHGAYGEKGQ 388

Query: 413  DGKPGDTGPQGF-PGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471
             G+P    P     G PG  GP G  G PG+      GP GPPG PG             
Sbjct: 389  KGEPAVVEPGMLVEGPPGPAGPAGIMGPPGL-----QGPTGPPGDPGD------------ 431

Query: 472  EGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGE----PGRFGVNSSDVP----------- 516
                        RGP G PG PG  G+PG PG     P R+G + S  P           
Sbjct: 432  ------------RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 479

Query: 517  ----------GPAGLPGVPGREGPPGFPGL---------PGPPGPPGREGPPGRTGQKGS 557
                      GP G  G+ GR GP G PG          PGP GP G +GPPG TG+ G 
Sbjct: 480  ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 539

Query: 558  LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS 617
             G  GA G +G  G PG  G RG  GL G PG  G  G  GP GPPG   P G D M G 
Sbjct: 540  RGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG---PPGDDGMRGE 596

Query: 618  GG-------PFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGL--- 667
             G       P  +  R   GP+G PG PG  G  GV G PG KG +G  G PG PG    
Sbjct: 597  DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 656

Query: 668  PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPG 727
            PG +G+ GPQGP G  G +G +G PG  G+  PG  GPPG PG      E+    L  PG
Sbjct: 657  PGPQGLPGPQGPIGPPGEKGPQGKPGLAGL--PGADGPPGHPGKEGQSGEK--GALGPPG 712

Query: 728  PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP----AQKGA 783
            P+G     G+PGP G KG  G +G +GS G KGE G PG  F  D G  G      Q G 
Sbjct: 713  PQGP---IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGP 767

Query: 784  KGEPGFRGP---------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG--DASLG 832
            +GE G  GP         PGP G+ G KG++G PG PG PG  G KG  G PG   A+  
Sbjct: 768  RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGE 827

Query: 833  FGMRGMPGPPGPPGPPGPPGT--------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGA 884
             G RG+ G PGP G  GP G         P         S   GPPG PG +GP GP+G 
Sbjct: 828  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887

Query: 885  KGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG---------- 934
             G  GP GPPG    D L       G  G RG+ G +G+ G PG GG  G          
Sbjct: 888  VGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP 941

Query: 935  ---SSLPGPPGPPGPRGYPGI---------PGPKGES-------IRGQPGP---PGPQGP 972
                  PGPPGPPG +G PG          PGP+G S       +RG PG    PG QG 
Sbjct: 942  IGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1001

Query: 973  PGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA--SSGVRL 1029
            PG+ G EG QGPPGP G PG     G     I +PG PGP GPPGP G  GA    G + 
Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1060

Query: 1030 WATRQAMLGQV----HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVA 1085
             A R  + G V       P G      ++ E+    Q G +  + E   P P G    V 
Sbjct: 1061 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120

Query: 1086 ALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSSYVHLR 1144
            A   P +   D  P PR +      +          PP     Q  PG P        + 
Sbjct: 1121 A---PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1177

Query: 1145 PARPTSPP 1152
            P  P  PP
Sbjct: 1178 PMGPPGPP 1185



 Score =  362 bits (929), Expect = 1e-99
 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%)

Query: 309  GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 360
            GA+  PG   +S  DG       PG R   G     GLKG +G  G PGP G  G  GS 
Sbjct: 967  GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1026

Query: 361  CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419
               GP GLP    P GP GPA +   PG +GP GP GRDG  G  G PG  G  G PG+ 
Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1086

Query: 420  GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 478
            G +G  G PG  G KGDKG+ G    GPPG QGP G PG +    +      +G  G  G
Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144

Query: 479  DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 538
            D     G RGFPGPPGP G+ GLPG PG  G N  DV GP G PG PG  GP G  G  G
Sbjct: 1145 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1198

Query: 539  PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 598
            P GPPG  G  G  G+KG  GEAG PG  G  G  GP G RGE G AG PG AGPPG  G
Sbjct: 1199 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1258

Query: 599  PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 636
            PPG                  PPG   PAG D + G     G P         G  GPPG
Sbjct: 1259 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1318

Query: 637  LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 679
             PG +G PG  G  G +GE GA G  G  G PG+ G  GPQGP                 
Sbjct: 1319 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1378

Query: 680  -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 704
                                     KGD GS+GEKG PG  G+          G  GLPG
Sbjct: 1379 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438

Query: 705  PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 758
              G PG     ++ DG +    GP G PG  G PGP GPKGN GS      KG+ G PGP
Sbjct: 1439 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1493

Query: 759  KGEKGEPGSIFSP 771
             G  G PG +  P
Sbjct: 1494 PGSPGPPGEVIQP 1506



 Score =  347 bits (891), Expect = 3e-95
 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%)

Query: 279  PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 330
            PV  P  AG  GS  ED    E+ E     S G +   G        G V  PG      
Sbjct: 1070 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1129

Query: 331  --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 385
              G   + G+ GQKG+ G  G PG  GP G   LPGPPG       V P+GP GP     
Sbjct: 1130 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1184

Query: 386  PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 442
            PGP+GP GP G DG    PG  G  G  GE G+PG+ G  G PG  G  GPKG++G+ G 
Sbjct: 1185 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1243

Query: 443  GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 502
             E GPPG  GPPG  GP                 G D     GP+G PGP G PG PG P
Sbjct: 1244 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1281

Query: 503  GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562
            GEPG           PAG  GV G +G  G PG PGPPGP G  GPPG  G++G  G AG
Sbjct: 1282 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1330

Query: 563  APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 622
            A G +G KGA G AGA G  G  G  GP GP G PGP G  G   P G   + G+ G   
Sbjct: 1331 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1387

Query: 623  STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682
                   GP GPPGLPGLKGD      PG+KGE       G PGL G  G  G QG KGD
Sbjct: 1388 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1433

Query: 683  RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741
            RG  G +G PG  G G  PG  GP GPPGP             +PGP+G  G  G  GPA
Sbjct: 1434 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1482

Query: 742  GPKGNLGSKGERGSPGPKGEKGEPGSIFS 770
            G KG+ G  G  GSPGP GE  +P  I S
Sbjct: 1483 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1511


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  533 bits (1374), Expect = e-151
 Identities = 395/1022 (38%), Positives = 445/1022 (43%), Gaps = 176/1022 (17%)

Query: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300
            G  S GA G+SG            + G      +  PP  T  P   G    D       
Sbjct: 545  GPGSSGAKGESG------------DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 592

Query: 301  EQTTVASLGAQTLPG--SDSVSTWDGSVRTPGGRVKEGGLKGQKGE------PGVPGPPG 352
            E       G   LPG   D     +   + P G   + G++G+ GE      PG  GP G
Sbjct: 593  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 652

Query: 353  RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412
              GP G+P  PG PG+     P GP G       GPQG PGPPG+ G PG  G PG  G 
Sbjct: 653  LLGPRGTPGAPGQPGMAGVDGPPGPKGNM-----GPQGEPGPPGQQGNPGPQGLPGPQGP 707

Query: 413  DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDK 465
             G PG+ GPQG PG  G  G  G  G PG        G  GPPGPQGP G PGP      
Sbjct: 708  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 767

Query: 466  LTFIDMEGS----------GFGGDLEALR--------GPRGFPGPPGPPGVPGLPGEPGR 507
                 ++GS          GF GD+            GPRG  GP GP G  G  G+PG 
Sbjct: 768  DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827

Query: 508  FG-VNSSDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGR 551
             G        G  GLPG PGR+GP      PGFPG         + G PGP G+ GP G 
Sbjct: 828  SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP 887

Query: 552  TGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 607
             G +G+ G  G PG KG+ G  GP G  GE G  G  GP G PGP GPPGPPG    PG 
Sbjct: 888  RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 947

Query: 608  PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGAD 659
            P      GF    G  GP         GPQGP G  G    +G PG PG PG +G  GA 
Sbjct: 948  PGQRGETGFQGKTGPPGP-----GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002

Query: 660  GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQ 718
            G  G  G PG +GI+G  GP G RG  GE+G PG  G  G  G  GP GPPGPV    E+
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062

Query: 719  DGSVLSVP-GPEGRPGFAGFPGPAGPKGNLGSKGERGS------------PGPKGEKGEP 765
              +  + P G  GRPG  G PGPAG KG  G KG +G             PGP G  G P
Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1122

Query: 766  GSIFSPDGGALG-PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824
            G     D G +G P QKG+KG+ G  GPPGP G  G  G  G  G  G PG  G +G  G
Sbjct: 1123 GE--DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFG 1180

Query: 825  EPGDASLGFGMRGMPGPPGP---PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGP 881
            + GD     G RG PGPPGP    G PGPPG    + +V       GPPG PG +GP GP
Sbjct: 1181 QKGDE----GARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGP 1232

Query: 882  KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG------- 934
             GA G  GPPG  G              GEKG+ G+AG  G  GE G GG  G       
Sbjct: 1233 NGADGPQGPPGSVGS---------VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1283

Query: 935  SSLPGPPGPPGPRGYPGIPGPKGE----SIRGQPGPPGPQGPPGI----GYEGRQGPPGP 986
            +  PG  GPPG +G PG  GPKG        G PGPPG  GP G     G +G  G PG 
Sbjct: 1284 AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343

Query: 987  PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEV--- 1043
            PGPPGP              GPPGPPG  GPPG  GA         RQ   G   E    
Sbjct: 1344 PGPPGPSG----------EAGPPGPPGKRGPPGAAGAEG-------RQGEKGAKGEAGAE 1386

Query: 1044 -PEGWLIFVAEQEELYVRVQNGFRKVQ---LEARTPLPRGTDNEVAALQPPVVQLHDSNP 1099
             P G    V  Q         G R +     E   P   G D     + PP +     +P
Sbjct: 1387 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1446

Query: 1100 YPRREHPHPTARPWRADDILASPP---------RLPEPQPYPGAPHHSSYVHLRPARPTS 1150
              + E  HP          L  PP          LP  Q  PGA          PA P  
Sbjct: 1447 GSKGEKGHPGLIG------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLG 1498

Query: 1151 PP 1152
            PP
Sbjct: 1499 PP 1500



 Score =  528 bits (1359), Expect = e-149
 Identities = 340/784 (43%), Positives = 380/784 (48%), Gaps = 113/784 (14%)

Query: 305  VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG 364
            V  +G +   G +      G    PG    + G KG+ G PG+PG PGR GP GS   PG
Sbjct: 801  VGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 859

Query: 365  PPGL------------PCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE 412
             PG             P P    GP GP  +   G +GP G PG  GT G DG PG PGE
Sbjct: 860  FPGANGEKGARGVAGKPGPRGQRGPTGP--RGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917

Query: 413  DGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDM 471
             G  G  GP GFPG  G  GP G  G PG  G+RG  G QG  GPPGP         +  
Sbjct: 918  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG------GVVGP 971

Query: 472  EG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------GPAGLPG 523
            +G +G  G +    G RG PGPPGPPG  GLPG  G+ G      P       GPAGL G
Sbjct: 972  QGPTGETGPI----GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1027

Query: 524  VPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAG 577
             PG  G PG  G PG      P GPPG  G PG  G  G+ G  G PG  G +G PGPAG
Sbjct: 1028 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1087

Query: 578  ARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQG 633
             +G  G  G  GPAG  G  GP G PGP  PAG    +G  G    P    ++   G  G
Sbjct: 1088 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147

Query: 634  PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPG 693
            PPG PGL+G  G PG+ G  GE G  G  G  G  G EG  G  GP G  G +G  G PG
Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207

Query: 694  KDG----VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG---- 745
            + G    VG  G PGPPGP GP       +G+     GP+G PG  G  G  G KG    
Sbjct: 1208 EKGENGDVGPMGPPGPPGPRGP----QGPNGA----DGPQGPPGSVGSVGGVGEKGEPGE 1259

Query: 746  --NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKG 803
              N G  GE G  GPKGE+GE G    P  GA GP   GAKG PG  GP G  G  G+ G
Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPP--GAAGPP--GAKGPPGDDGPKGNPGPVGFPG 1315

Query: 804  EIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863
            + G PG PG  G +G+ G+KGE GD        G PGPPGP G  GPPG P         
Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPP--------- 1359

Query: 864  SSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGE 923
              + GPPG  G +G  G KGAKGE G  GPPG+      Q  A   G +G RG  G  GE
Sbjct: 1360 -GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1418

Query: 924  RGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGES----------------IRGQPGPP 967
            +G PG  G  G   PGP GPPG  G  G PG KGE                  +G  G P
Sbjct: 1419 QGLPGAAGQDGP--PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476

Query: 968  GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH--RQTISVPGP---------PGPPGPP 1015
            G QG PG  G  G  GP GP GPPGPP  PGP   +      GP         PGPPG P
Sbjct: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536

Query: 1016 GPPG 1019
            GPPG
Sbjct: 1537 GPPG 1540



 Score =  496 bits (1277), Expect = e-140
 Identities = 339/846 (40%), Positives = 385/846 (45%), Gaps = 187/846 (22%)

Query: 329  PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPL----------GPA 378
            P G     G  G +G  G PG PG  GPPG P LPG  GLP P   +          G  
Sbjct: 446  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505

Query: 379  GP------------------ALQTVPGPQ------GPPGPPGRDGTPGRDGEP------- 407
            GP                  AL+  PGP       GP G PG  G  G  G+P       
Sbjct: 506  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565

Query: 408  --------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 455
                    G PG+ G+PG  G +G PG PG  G +G  G PG+    G RG  GPQGPPG
Sbjct: 566  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
            PPG      +   I   G         L GPRG PG PG PG+ G+ G PG  G      
Sbjct: 626  PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG-----N 680

Query: 516  PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575
             GP G PG PG++G PG  GLPGP GP    GPPG  G +G  G AG PG  G  G PG 
Sbjct: 681  MGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAGLPGADGPPGHPGK 737

Query: 576  AGARGESGLAGAPGPAGPPGPPGPPGPPG----------------PGLPAGFDDM--EGS 617
             G  GE G  G PGP GP G PGP G  G                 G P    DM  +G 
Sbjct: 738  EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 797

Query: 618  GGPFWSTA-RSADGPQGPPGLPGLKGD---------------PGVPGLPGAKGEVGADGV 661
             G       R  DGP+GP G  G  GD               PG+PG PG +G  G+ G 
Sbjct: 798  RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857

Query: 662  PGFPGL------------PGREGIAGPQGPKGDRGSRGEKGDPGKDGV-------GQPGL 702
            PGFPG             PG  G  GP GP+G RG+RG  G PG  G        G PG 
Sbjct: 858  PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917

Query: 703  PGPPGPPGPVVYVSE--------QDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754
             GP GP GPV +           +DG +   PG  G  GF G  GP GP G +G +G  G
Sbjct: 918  RGPQGPQGPVGFPGPKGPPGPPGKDG-LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 976

Query: 755  SPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEP---GFRGPPGPYGRPGYKGEIGFPG 809
              GP GE+G PG    P + G  G A K GAKG+P   G  G  GP G  G+ GE G PG
Sbjct: 977  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036

Query: 810  RPGRPGMNGLKGEKGEPGD-------ASLG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861
              G PG+ G +G +G PG         S G  G  G+PG PGP GPPGP G         
Sbjct: 1037 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG--------- 1087

Query: 862  AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQK 921
                  G PG  G QGP G  G +G VG PGP G          A   GE GD+G+ G+ 
Sbjct: 1088 ----EKGAPGEKGPQGPAGRDGVQGPVGLPGPAG---------PAGSPGEDGDKGEIGEP 1134

Query: 922  GERGEPGGGGFFGSSLPGPPGPPGPRGYPGI------PGPKG----------ESIRGQPG 965
            G++G  G  G  G   PGPPG  GP G PGI      PGP+G          E  RG PG
Sbjct: 1135 GQKGSKGDKGENGP--PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192

Query: 966  PPGP---QGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTM 1021
            PPGP   QG PG  G +G  G  GP GPPGPP   GP        GP G  GP GPPG++
Sbjct: 1193 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ-------GPNGADGPQGPPGSV 1245

Query: 1022 GASSGV 1027
            G+  GV
Sbjct: 1246 GSVGGV 1251



 Score =  457 bits (1177), Expect = e-128
 Identities = 399/1213 (32%), Positives = 498/1213 (41%), Gaps = 188/1213 (15%)

Query: 67   AYVFGPDANSGQVARYHFPS-LFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL 125
            AY     A      +  FP   F  DFS+LF ++P       L +I +        G++ 
Sbjct: 73   AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEH------GIQQ 126

Query: 126  SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFV-GQWTHLALSVAGGFVALYVDCEEFQ 184
             GV+ G   + L     G         FR      G+W  +A+SV    V + VDC++  
Sbjct: 127  IGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKT 186

Query: 185  RMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDS 244
              PL RS R +    G  +F  +    D + F+G I +  +  DP+ +  +C +    D 
Sbjct: 187  TKPLDRSERAIVDTNGITVFGTRI--LDEEVFEGDIQQFLITGDPKAAYDYC-EHYSPDC 243

Query: 245  DGASGDSGSG-------------------LGDAR----------ELLREETGAALKPRL- 274
            D ++  +                       G+A             + EET A  +  + 
Sbjct: 244  DSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEANIV 303

Query: 275  ---------PAPPPVTTPPLAGGSSTEDSRSEEV--EEQTTVASLGAQ------TLPGSD 317
                           T  P     + E +  EE+  EE  T     +Q      TL  + 
Sbjct: 304  DDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENK 363

Query: 318  SVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGP 377
             +   D  +   G   +    + ++ E     PP     PG P           ++    
Sbjct: 364  EIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPA-------ETDITETSI 416

Query: 378  AGPALQTVPGPQGPPG--PPGR--DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGP 433
             G       G +G P    PG   +G PG  G  G  G  G  G TGP   PG PGD GP
Sbjct: 417  NGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---PGDPGDRGP 473

Query: 434  KGDKGDPGV-GERGPPGPQ-------GPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG 485
             G  G PG  G  GPPG         G  G  GP+        I  + +     L+  R 
Sbjct: 474  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT--------ISAQEAQAQAILQQAR- 524

Query: 486  PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR 545
                 GPPGP G+ G PG  G         PG +G  G  G  GP G  G+ GPPGP G+
Sbjct: 525  -IALRGPPGPMGLTGRPGPVGG--------PGSSGAKGESGDPGPQGPRGVQGPPGPTGK 575

Query: 546  EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP 605
             G  GR G  G  G  G PG KG +G  G  G  G+ G  G  GP GPPGPPG  G  G 
Sbjct: 576  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 635

Query: 606  GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 665
                G   + G  GP     R   GP+G PG PG  G  GV G PG KG +G  G PG P
Sbjct: 636  DGEIGPRGLPGEAGP-----RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPP 690

Query: 666  GL---PGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSV 722
            G    PG +G+ GPQGP G  G +G +G PG  G+  PG  GPPG PG      E+    
Sbjct: 691  GQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGL--PGADGPPGHPGKEGQSGEK--GA 746

Query: 723  LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP---- 778
            L  PGP+G     G+PGP G KG  G +G +GS G KGE G PG  F  D G  G     
Sbjct: 747  LGPPGPQGP---IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG--FKGDMGLKGDRGEV 801

Query: 779  AQKGAKGEPGFRGP---------PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-- 827
             Q G +GE G  GP         PGP G+ G KG++G PG PG PG  G KG  G PG  
Sbjct: 802  GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP 861

Query: 828  DASLGFGMRGMPGPPGPPGPPGPPGT--------PVYDSNVFAESSRPGPPGLPGNQGPP 879
             A+   G RG+ G PGP G  GP G         P         S   GPPG PG +GP 
Sbjct: 862  GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ 921

Query: 880  GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG----- 934
            GP+G  G  GP GPPG    D L       G  G RG+ G +G+ G PG GG  G     
Sbjct: 922  GPQGPVGFPGPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 975

Query: 935  --------SSLPGPPGPPGPRGYPGI---------PGPKGES-------IRGQPGP---P 967
                       PGPPGPPG +G PG          PGP+G S       +RG PG    P
Sbjct: 976  GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 1035

Query: 968  GPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA--S 1024
            G QG PG+ G EG QGPPGP G PG     G     I +PG PGP GPPGP G  GA   
Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGE 1094

Query: 1025 SGVRLWATRQAMLGQV----HEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGT 1080
             G +  A R  + G V       P G      ++ E+    Q G +  + E   P P G 
Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154

Query: 1081 DNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSS 1139
               V A   P +   D  P PR +      +          PP     Q  PG P     
Sbjct: 1155 QGPVGA---PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1211

Query: 1140 YVHLRPARPTSPP 1152
               + P  P  PP
Sbjct: 1212 NGDVGPMGPPGPP 1224



 Score =  362 bits (929), Expect = 1e-99
 Identities = 236/553 (42%), Positives = 260/553 (47%), Gaps = 103/553 (18%)

Query: 309  GAQTLPGSDSVSTWDGSVRT---PGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 360
            GA+  PG   +S  DG       PG R   G     GLKG +G  G PGP G  G  GS 
Sbjct: 1006 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1065

Query: 361  CLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419
               GP GLP    P GP GPA +   PG +GP GP GRDG  G  G PG  G  G PG+ 
Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGED 1125

Query: 420  GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGG 478
            G +G  G PG  G KGDKG+ G    GPPG QGP G PG +    +      +G  G  G
Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENG--PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183

Query: 479  DLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPG 538
            D     G RGFPGPPGP G+ GLPG PG  G N  DV GP G PG PG  GP G  G  G
Sbjct: 1184 D----EGARGFPGPPGPIGLQGLPGPPGEKGENG-DV-GPMGPPGPPGPRGPQGPNGADG 1237

Query: 539  PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 598
            P GPPG  G  G  G+KG  GEAG PG  G  G  GP G RGE G AG PG AGPPG  G
Sbjct: 1238 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1297

Query: 599  PPG------------------PPGPGLPAGFDDMEGS----GGPFWSTARSADGPQGPPG 636
            PPG                  PPG   PAG D + G     G P         G  GPPG
Sbjct: 1298 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1357

Query: 637  LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP----------------- 679
             PG +G PG  G  G +GE GA G  G  G PG+ G  GPQGP                 
Sbjct: 1358 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1417

Query: 680  -------------------------KGDRGSRGEKGDPGKDGV----------GQPGLPG 704
                                     KGD GS+GEKG PG  G+          G  GLPG
Sbjct: 1418 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477

Query: 705  PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGS------KGERGSPGP 758
              G PG     ++ DG +    GP G PG  G PGP GPKGN GS      KG+ G PGP
Sbjct: 1478 TQGSPG-----AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1532

Query: 759  KGEKGEPGSIFSP 771
             G  G PG +  P
Sbjct: 1533 PGSPGPPGEVIQP 1545



 Score =  347 bits (891), Expect = 3e-95
 Identities = 226/509 (44%), Positives = 251/509 (49%), Gaps = 84/509 (16%)

Query: 279  PVTTPPLAG--GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG------ 330
            PV  P  AG  GS  ED    E+ E     S G +   G        G V  PG      
Sbjct: 1109 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168

Query: 331  --GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP---VSPLGPAGPALQTV 385
              G   + G+ GQKG+ G  G PG  GP G   LPGPPG       V P+GP GP     
Sbjct: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP----- 1223

Query: 386  PGPQGPPGPPGRDGT---PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV 442
            PGP+GP GP G DG    PG  G  G  GE G+PG+ G  G PG  G  GPKG++G+ G 
Sbjct: 1224 PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG- 1282

Query: 443  GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLP 502
             E GPPG  GPPG  GP                 G D     GP+G PGP G PG PG P
Sbjct: 1283 -EAGPPGAAGPPGAKGPP----------------GDD-----GPKGNPGPVGFPGDPGPP 1320

Query: 503  GEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562
            GEPG           PAG  GV G +G  G PG PGPPGP G  GPPG  G++G  G AG
Sbjct: 1321 GEPG-----------PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1369

Query: 563  APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW 622
            A G +G KGA G AGA G  G  G  GP GP G PGP G  G   P G   + G+ G   
Sbjct: 1370 AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG--- 1426

Query: 623  STARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682
                   GP GPPGLPGLKGD      PG+KGE       G PGL G  G  G QG KGD
Sbjct: 1427 --QDGPPGPMGPPGLPGLKGD------PGSKGE------KGHPGLIGLIGPPGEQGEKGD 1472

Query: 683  RGSRGEKGDPGKDGVGQ-PGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741
            RG  G +G PG  G G  PG  GP GPPGP             +PGP+G  G  G  GPA
Sbjct: 1473 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-----------GLPGPQGPKGNKGSTGPA 1521

Query: 742  GPKGNLGSKGERGSPGPKGEKGEPGSIFS 770
            G KG+ G  G  GSPGP GE  +P  I S
Sbjct: 1522 GQKGDSGLPGPPGSPGPPGEVIQPLPILS 1550


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  530 bits (1365), Expect = e-150
 Identities = 407/1117 (36%), Positives = 460/1117 (41%), Gaps = 252/1117 (22%)

Query: 239  EEGDDSD-GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 297
            E+G   D G  G+ G+     R+    E G    P  P PP    PP  GG+        
Sbjct: 130  EQGPRGDRGDKGEKGAPGPRGRD---GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 186

Query: 298  EVEEQTTVASLGAQTLP-GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 356
              +E+   A LG    P G        G    PG +  +G   G+ GEPGV GP G  GP
Sbjct: 187  -FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN-PGEPGEPGVSGPMGPRGP 244

Query: 357  PGSPCLPGP------PGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGT------ 400
            PG P  PG       PG      P GP G    P    +PG +G  G PG DG       
Sbjct: 245  PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 304

Query: 401  PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 460
            PG  GE G PGE+G PG  GP+G PG  G  GP G  G    G  G PGP GPPGP GP+
Sbjct: 305  PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG--ARGNDGQPGPAGPPGPVGPA 362

Query: 461  FRHDKLTFIDMEGSGFGG--------------DLEALRGPRGFPGPPGPPGVPGLPGEPG 506
                        G GF G                E  +GPRG PG PG PG  G  G PG
Sbjct: 363  -----------GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 411

Query: 507  RFGV----NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562
              G+     S+  PG AG PG PG  GPPG  G  GP GP G+ G PG  G KG  G  G
Sbjct: 412  TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 471

Query: 563  APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG------------------ 604
             PG  G +GAPGPAG  G+ G  G PG  GP GPPG  G PG                  
Sbjct: 472  EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531

Query: 605  ----------------------PGLPA--GFDDMEGSGGPFW----STARSADGPQGPPG 636
                                  PGLP   G     G  GP      S A   DG  GPPG
Sbjct: 532  ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 591

Query: 637  LPGLKGDPGVPGLPGAK---------GEVGADGVPGFPGLPGRE---GIAGPQGPKGDRG 684
              G +G PGV G PG K         GE G  G PG  GLPG++   G AGP GP G  G
Sbjct: 592  PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 651

Query: 685  SRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 744
             RGE+G PG  G    GLPGPPGPPG       + G     PG +G PG AG PG  GP+
Sbjct: 652  ERGEQGAPGPSGF--QGLPGPPGPPG-------EGGK----PGDQGVPGEAGAPGLVGPR 698

Query: 745  GNLGSKGERGSPGPKGEKGEPGSIFSP--DG--GALGPA-QKGAKGEPGFR--------- 790
            G  G  GERGSPG +G +G  G   +P  DG  GA GPA   GA+G PG +         
Sbjct: 699  GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 758

Query: 791  ---------------------------------GPPGPYGRPGYKGEIGFPGRPGRPGMN 817
                                             GPPGP G  G KGE+G PG  G  G  
Sbjct: 759  GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818

Query: 818  GLKGEKGEPG-DASLGF----------------------GMRGMPGPPGPPGPPGPPGT- 853
            G  GE+GE G     GF                      G  G PGP GP G PGP G  
Sbjct: 819  GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878

Query: 854  -------------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP------PGPP 894
                         P   +     + R GPPG  GN GPPGP G  G+ GP       GPP
Sbjct: 879  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938

Query: 895  GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 953
            G+     LQ  A   GEKG+ GD G  G  G PG  G  G   + G PG  G RG+PG+P
Sbjct: 939  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998

Query: 954  GPKGE-------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFPG----- 997
            GP GE          G  GPPGP GPPG+    G  GR+G PG  GPPG     G     
Sbjct: 999  GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 1058

Query: 998  PHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLG----------QVHEVPEGW 1047
                 +  PG PGPPG PGP G  G   G R  A  Q  +G          Q  + P G 
Sbjct: 1059 GETGAVGAPGAPGPPGSPGPAGPTG-KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1117

Query: 1048 LIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQP-----PVVQLHDSNPYPR 1102
                 E  E  ++   GF  +Q     P P G         P     P   +  S     
Sbjct: 1118 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA 1177

Query: 1103 REHPHPTARPW----RADDILASPPRLPEPQPYPGAP 1135
               P P   P       +   A PP  P P   PG P
Sbjct: 1178 NGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214



 Score =  528 bits (1361), Expect = e-149
 Identities = 351/888 (39%), Positives = 407/888 (45%), Gaps = 163/888 (18%)

Query: 250  DSGSGLGDARELLREETGAALKPRLPAPP--PVTTPPLAGGSSTEDSRSEEVEEQTTVAS 307
            D+G+ L D  +++ E+    L P +P     P+    LA  S     + ++ E       
Sbjct: 58   DTGTVLCD--DIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDI 115

Query: 308  LGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPG 367
            +G +  PG             P G     G +G KGE G PGP GR G PG+P  PGPPG
Sbjct: 116  VGPKGPPGPQG----------PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 165

Query: 368  LPCPVSP---------------------------LGPAGPALQTVPGPQGPPGPPGRDGT 400
             P P  P                            GP GP      GP+GPPGP G  G 
Sbjct: 166  PPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM-----GPRGPPGPAGAPGP 220

Query: 401  PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGP---PGP 456
             G  G PG+PGE G  G  GP+G PG PG  G  G+ G PG  GERGPPGPQG    PG 
Sbjct: 221  QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGT 280

Query: 457  PGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGV--- 510
            PG         +  ++G+        ++G  G P   G PGP G  GLPGE GR G    
Sbjct: 281  PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGA 340

Query: 511  ----NSSDVPGPAGLPGVPGREGPPGFPGLPGPP---------GPPGREGPPGRTGQKGS 557
                 +   PGPAG PG  G  G PGFPG PG           GP G +GP G  G  GS
Sbjct: 341  AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 400

Query: 558  LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLP------AGF 611
             G AGA G+ G+ G PG  G+ G  G+AGAPG  GP GPPGP G  GP  P       G 
Sbjct: 401  PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460

Query: 612  DDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD---GVPGFPGLP 668
               +G  GP      +  GPQG PG  G +G  G  G PG  G +G     G PG  G P
Sbjct: 461  AGFKGEQGPKGEPGPA--GPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 518

Query: 669  GREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPG 727
            G++G+AGP+G  G+RG  G  G  G +  G PG PG PG PG         D       G
Sbjct: 519  GQDGLAGPKGAPGERGPSGLAGPKGAN--GDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 576

Query: 728  PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 787
            P G PG  G PGP GP+G  G  G  G PGPKG  GEPG                  GE 
Sbjct: 577  PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK----------------AGEK 620

Query: 788  GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGP 847
            G  G PG  G PG  GE G  G PG  G  G +GE+G PG +    G +G+PGPPGPPG 
Sbjct: 621  GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS----GFQGLPGPPGPPGE 676

Query: 848  PGPPGTPVYDSNVFAESSRP------------------------GPPGLPGNQGPPGPKG 883
             G PG    D  V  E+  P                        GP GLPG  G  GPKG
Sbjct: 677  GGKPG----DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 732

Query: 884  AKGEVGPP---GPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 940
            A G  GPP   GPPG       +  A + G KGDRGD G+KG  G PG  G  G  L GP
Sbjct: 733  ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG--GRGLTGP 790

Query: 941  PGPPGP------RGYPGIPGPKGES-------IRGQPGPPGP---QGPPGI--------- 975
             GPPGP      +G  G PGP G +        RG+ GPPGP    GPPG          
Sbjct: 791  IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850

Query: 976  -GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
             G  G++G  G PGP GP   PGP   T  V GP G  G  GPPG  G
Sbjct: 851  QGEAGQKGDAGAPGPQGPSGAPGPQGPT-GVTGPKGARGAQGPPGATG 897



 Score =  518 bits (1334), Expect = e-146
 Identities = 331/766 (43%), Positives = 374/766 (48%), Gaps = 99/766 (12%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368
            G +  PG D ++   G    PG R    GL G KG  G PG PG  G PG+  L G PG 
Sbjct: 513  GNRGFPGQDGLA---GPKGAPGER-GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 568

Query: 369  PCPVSPLGPAG-PALQTVPGPQGP------------PGPPGRDGTPGRDGE---PGDPGE 412
              P   +GP+G P     PGP GP            PGP G +G PG+ GE   PG PG 
Sbjct: 569  AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 628

Query: 413  DGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDME 472
             G PG  G  G  G PG  GP G++G+ G    GP G QG PGPPGP     K     + 
Sbjct: 629  RGLPGKDGETGAAGPPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGGKPGDQGVP 686

Query: 473  GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREGPP 531
            G      L   RG RGFPG  G PG  GL G  G  G   +D P G +G  G PG +GPP
Sbjct: 687  GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 746

Query: 532  GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA------PGPAGARGESGLA 585
            G  G+PG  G  G  GP G  G  G  G  GAPG  G +G       PGPAGA GE G  
Sbjct: 747  GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806

Query: 586  GAPGPAGPPGP---------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD----GPQ 632
            G PGPAG  G           GPPGP G   P G D   G+ G      +  D    GPQ
Sbjct: 807  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866

Query: 633  GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR---------EGIAGPQGPKGDR 683
            GP G PG +G  GV G  GA+G  G  G  GFPG  GR          G  GP GP G  
Sbjct: 867  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926

Query: 684  GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742
            G +G +GD G  G  G+PGL GP GPPG                G  G  G +G  GP G
Sbjct: 927  GPKGARGDSGPPGRAGEPGLQGPAGPPGE--------------KGEPGDDGPSGAEGPPG 972

Query: 743  PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 802
            P+G  G +G  G PG +GE+G PG +  P G    P ++GA G  G RGPPGP G PG  
Sbjct: 973  PQGLAGQRGIVGLPGQRGERGFPG-LPGPSGE---PGKQGAPGASGDRGPPGPVGPPGLT 1028

Query: 803  GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862
            G  G PGR G PG +G  G  G  G      G RG  G  G PG PGPPG+P        
Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVK----GDRGETGAVGAPGAPGPPGSP-------- 1076

Query: 863  ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922
                 GP G  G QG  G  GA+G +GP GP G       Q      G +GD+G+AG+ G
Sbjct: 1077 -----GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ------GPRGDKGEAGEPG 1125

Query: 923  ERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQ 981
            ERG  G  GF G  L G PGPPGP G  G  GP G S  G  GPPGP GP G  G  G  
Sbjct: 1126 ERGLKGHRGFTG--LQGLPGPPGPSGDQGASGPAGPS--GPRGPPGPVGPSGKDGANGIP 1181

Query: 982  GPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
            GP GPPGP G     GP     + PGPPGPPGPPGP   M A +G+
Sbjct: 1182 GPIGPPGPRGRSGETGPAGPPGN-PGPPGPPGPPGPGIDMSAFAGL 1226



 Score =  404 bits (1037), Expect = e-112
 Identities = 280/742 (37%), Positives = 332/742 (44%), Gaps = 114/742 (15%)

Query: 246  GASGDSGS----GLGDARELLREE-----------TGAALKPRLPAPPPVT----TPPLA 286
            GA+GD G     GL  AR L               +GA  +   P PP        P + 
Sbjct: 543  GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 602

Query: 287  GGSSTEDSRSE--EVEEQTTVASLGAQTLPGSDS---VSTWDGSVRTPGGRVKEG--GLK 339
            G    + +  E  +  E+    + G + LPG D     +   G     G R ++G  G  
Sbjct: 603  GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 662

Query: 340  GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRD 398
            G +G PG PGPPG  G PG   +PG  G P  V P G  G P  +  PG QG  GP G  
Sbjct: 663  GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 722

Query: 399  GTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGPKGDKGDPGVGERGPPGPQG 452
            GTPG DG  G  G  G PG  GP G  G PG+       GPKGD+GD  VGE+GP G  G
Sbjct: 723  GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD--VGEKGPEGAPG 780

Query: 453  ---------PPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 503
                     P GPPGP+  + +   +   G           G RG  GPPGP G  G PG
Sbjct: 781  KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840

Query: 504  EPGRFGVNSSD----------VPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTG 553
              G+ G                PGP G  G PG +GP G   + GP G  G +GPPG TG
Sbjct: 841  ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG---VTGPKGARGAQGPPGATG 897

Query: 554  QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 613
              G+ G  G PG  G+ G PGP G  G+ G  GA G +GPPG  G PG  GP  P G   
Sbjct: 898  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957

Query: 614  MEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGF--- 664
              G  GP  S A    GPQG  G      LPG +G+ G PGLPG  GE G  G PG    
Sbjct: 958  EPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD 1015

Query: 665  ---------PGL------PGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 708
                     PGL      PGREG  G  GP G  G+ G KGD G+ G VG PG PGPPG 
Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075

Query: 709  PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768
            PGP               G +G  G AG  GP GP G  G++G +G  GP+G+KGE G  
Sbjct: 1076 PGPA-----------GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE- 1123

Query: 769  FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828
                     P ++G KG  GF G  G  G PG  G+ G  G  G  G  G  G  G  G 
Sbjct: 1124 ---------PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1174

Query: 829  ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 888
                 G  G+PGP GPPGP G  G    ++        PGPPG PG  GP     A   +
Sbjct: 1175 D----GANGIPGPIGPPGPRGRSG----ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1226

Query: 889  GPPGPPGQFPFDFLQLEAEMKG 910
            G P   G  P  +++ +    G
Sbjct: 1227 G-PREKGPDPLQYMRADQAAGG 1247



 Score =  372 bits (955), Expect = e-102
 Identities = 258/648 (39%), Positives = 293/648 (45%), Gaps = 105/648 (16%)

Query: 242  DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 301
            D   GA+G  G   G A E  R E GA         P    PP  GG   +     E   
Sbjct: 635  DGETGAAGPPGPA-GPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691

Query: 302  QTTVA------------SLGAQTL---------PGSDSVSTWDGSVRTPGGRVKEG--GL 338
               V             S GAQ L         PG+D      G    PG +   G  G+
Sbjct: 692  PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751

Query: 339  KGQKGEPGVPGPPG------RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 392
             G++G  G+ GP G        GP G+P   G  GL  P+ P GPAG       G +G  
Sbjct: 752  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG-----ANGEKGEV 806

Query: 393  GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQ 451
            GPPG  G+ G  G PG+ GE G PG  G  G PG  G  G KG++G+ G  G+ G PGPQ
Sbjct: 807  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866

Query: 452  GP---PGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGPPGVPGLPGE 504
            GP   PGP GP+           +G    +GF G    + GP G  G PGPPG PG  G+
Sbjct: 867  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV-GPPGSNGNPGPPGPPGPSGK 925

Query: 505  PGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563
             G  G    S  PG AG PG+ G  GPPG  G PG  GP G EGPPG  G  G  G  G 
Sbjct: 926  DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 985

Query: 564  PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 623
            PG +G +G PG  G  GE G  GAPG +G  GPPGP GPPG   PAG    EGS G    
Sbjct: 986  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG---- 1041

Query: 624  TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDR 683
                ADGP G  G  G+KGD         +GE GA G PG PG PG  G AGP G +GDR
Sbjct: 1042 ----ADGPPGRDGAAGVKGD---------RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088

Query: 684  GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742
            G  G +G  G  G  G  G+ GP GP G      E     L   G  G  G  G PGP G
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK--GHRGFTGLQGLPGPPG 1146

Query: 743  PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 802
            P G+ G+ G  G  GP+G  G  G    P G      + GA G PG  GPPGP GR G  
Sbjct: 1147 PSGDQGASGPAGPSGPRGPPGPVG----PSG------KDGANGIPGPIGPPGPRGRSGET 1196

Query: 803  GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGP 850
            G  G PG P                            GPPGPPGPPGP
Sbjct: 1197 GPAGPPGNP----------------------------GPPGPPGPPGP 1216



 Score =  234 bits (598), Expect = 3e-61
 Identities = 164/461 (35%), Positives = 188/461 (40%), Gaps = 58/461 (12%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G  G +GS         R ETG       P P     PP A G         E  ++   
Sbjct: 807  GPPGPAGSAGARGAPGERGETGP------PGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 860

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 365
             + G Q   G+       G     G R    G +G  G  G PG  GR GPPGS   PGP
Sbjct: 861  GAPGPQGPSGAPGPQGPTGVTGPKGAR----GAQGPPGATGFPGAAGRVGPPGSNGNPGP 916

Query: 366  PGLPCPVSPLGPAG-------PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 415
            PG P P    GP G       P     PG QGP GPPG  G PG DG  G  G  G    
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976

Query: 416  ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 465
                     PG  G +GFPG PG  G  G +G PG  G+RGPPGP GPPG  GP+    +
Sbjct: 977  AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036

Query: 466  LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----------- 514
                  +G         ++G RG  G  G PG PG PG PG  G                
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096

Query: 515  --VPGPAGLPGVPGREGP---------PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563
                GPAG  G+ G +GP         PG  GL G  G  G +G PG  G  G  G +G 
Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156

Query: 564  PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGS 617
             G  G +G PGP G  G+ G  G PGP GPPGP       GP GPPG   P G     G 
Sbjct: 1157 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216

Query: 618  GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGA 658
            G    + A      +GP  L  ++ D    GL     EV A
Sbjct: 1217 GIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDA 1257



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 79/244 (32%), Positives = 92/244 (37%), Gaps = 49/244 (20%)

Query: 916  GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI 975
            G  G KG++GEPG        + GP GPPGP+G  G  GP+G+  RG  G  G  GP   
Sbjct: 98   GQPGPKGQKGEPGDI----KDIVGPKGPPGPQGPAGEQGPRGD--RGDKGEKGAPGP--- 148

Query: 976  GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQA 1035
               GR G PG PG PGPP             GPPGPPGPPG  G   A            
Sbjct: 149  --RGRDGEPGTPGNPGPP-------------GPPGPPGPPGLGGNFAAQ----------- 182

Query: 1036 MLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLH 1095
            M G   E   G  + V +          G R     A  P P+G          P V   
Sbjct: 183  MAGGFDEKAGGAQLGVMQGP----MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV--- 235

Query: 1096 DSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHS 1155
             S P   R  P P  +P   DD  A  P     +  PG      +    P  P  P    
Sbjct: 236  -SGPMGPRGPPGPPGKP--GDDGEAGKPGKAGERGPPGPQGARGF----PGTPGLPGVKG 288

Query: 1156 HRDF 1159
            HR +
Sbjct: 289  HRGY 292


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  530 bits (1365), Expect = e-150
 Identities = 407/1117 (36%), Positives = 460/1117 (41%), Gaps = 252/1117 (22%)

Query: 239  EEGDDSD-GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSE 297
            E+G   D G  G+ G+     R+    E G    P  P PP    PP  GG+        
Sbjct: 61   EQGPRGDRGDKGEKGAPGPRGRD---GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117

Query: 298  EVEEQTTVASLGAQTLP-GSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 356
              +E+   A LG    P G        G    PG +  +G   G+ GEPGV GP G  GP
Sbjct: 118  -FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN-PGEPGEPGVSGPMGPRGP 175

Query: 357  PGSPCLPGP------PGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGT------ 400
            PG P  PG       PG      P GP G    P    +PG +G  G PG DG       
Sbjct: 176  PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGA 235

Query: 401  PGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 460
            PG  GE G PGE+G PG  GP+G PG  G  GP G  G    G  G PGP GPPGP GP+
Sbjct: 236  PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG--ARGNDGQPGPAGPPGPVGPA 293

Query: 461  FRHDKLTFIDMEGSGFGG--------------DLEALRGPRGFPGPPGPPGVPGLPGEPG 506
                        G GF G                E  +GPRG PG PG PG  G  G PG
Sbjct: 294  -----------GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 342

Query: 507  RFGV----NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAG 562
              G+     S+  PG AG PG PG  GPPG  G  GP GP G+ G PG  G KG  G  G
Sbjct: 343  TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 402

Query: 563  APGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG------------------ 604
             PG  G +GAPGPAG  G+ G  G PG  GP GPPG  G PG                  
Sbjct: 403  EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 462

Query: 605  ----------------------PGLPA--GFDDMEGSGGPFW----STARSADGPQGPPG 636
                                  PGLP   G     G  GP      S A   DG  GPPG
Sbjct: 463  ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 522

Query: 637  LPGLKGDPGVPGLPGAK---------GEVGADGVPGFPGLPGRE---GIAGPQGPKGDRG 684
              G +G PGV G PG K         GE G  G PG  GLPG++   G AGP GP G  G
Sbjct: 523  PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 582

Query: 685  SRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPK 744
             RGE+G PG  G    GLPGPPGPPG       + G     PG +G PG AG PG  GP+
Sbjct: 583  ERGEQGAPGPSGF--QGLPGPPGPPG-------EGGK----PGDQGVPGEAGAPGLVGPR 629

Query: 745  GNLGSKGERGSPGPKGEKGEPGSIFSP--DG--GALGPA-QKGAKGEPGFR--------- 790
            G  G  GERGSPG +G +G  G   +P  DG  GA GPA   GA+G PG +         
Sbjct: 630  GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA 689

Query: 791  ---------------------------------GPPGPYGRPGYKGEIGFPGRPGRPGMN 817
                                             GPPGP G  G KGE+G PG  G  G  
Sbjct: 690  GIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 749

Query: 818  GLKGEKGEPG-DASLGF----------------------GMRGMPGPPGPPGPPGPPGT- 853
            G  GE+GE G     GF                      G  G PGP GP G PGP G  
Sbjct: 750  GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809

Query: 854  -------------PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGP------PGPP 894
                         P   +     + R GPPG  GN GPPGP G  G+ GP       GPP
Sbjct: 810  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869

Query: 895  GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 953
            G+     LQ  A   GEKG+ GD G  G  G PG  G  G   + G PG  G RG+PG+P
Sbjct: 870  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929

Query: 954  GPKGE-------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFPG----- 997
            GP GE          G  GPPGP GPPG+    G  GR+G PG  GPPG     G     
Sbjct: 930  GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 989

Query: 998  PHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLG----------QVHEVPEGW 1047
                 +  PG PGPPG PGP G  G   G R  A  Q  +G          Q  + P G 
Sbjct: 990  GETGAVGAPGAPGPPGSPGPAGPTG-KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1048

Query: 1048 LIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQP-----PVVQLHDSNPYPR 1102
                 E  E  ++   GF  +Q     P P G         P     P   +  S     
Sbjct: 1049 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA 1108

Query: 1103 REHPHPTARPW----RADDILASPPRLPEPQPYPGAP 1135
               P P   P       +   A PP  P P   PG P
Sbjct: 1109 NGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145



 Score =  523 bits (1347), Expect = e-148
 Identities = 335/807 (41%), Positives = 378/807 (46%), Gaps = 149/807 (18%)

Query: 329  PGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSP-------------- 374
            P G     G +G KGE G PGP GR G PG+P  PGPPG P P  P              
Sbjct: 58   PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117

Query: 375  -------------LGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP 421
                          GP GP      GP+GPPGP G  G  G  G PG+PGE G  G  GP
Sbjct: 118  FDEKAGGAQLGVMQGPMGPM-----GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP 172

Query: 422  QGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGP---PGPPGPSFRHDKLTFIDMEGSGFG 477
            +G PG PG  G  G+ G PG  GERGPPGPQG    PG PG         +  ++G+   
Sbjct: 173  RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGE 232

Query: 478  GDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGV-------NSSDVPGPAGLPGVPGR 527
                 ++G  G P   G PGP G  GLPGE GR G         +   PGPAG PG  G 
Sbjct: 233  AGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP 292

Query: 528  EGPPGFPGLPGPP---------GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGA 578
             G PGFPG PG           GP G +GP G  G  GS G AGA G+ G+ G PG  G+
Sbjct: 293  AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 352

Query: 579  RGESGLAGAPGPAGPPGPPGPPGPPGPGLP------AGFDDMEGSGGPFWSTARSADGPQ 632
             G  G+AGAPG  GP GPPGP G  GP  P       G    +G  GP      +  GPQ
Sbjct: 353  AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA--GPQ 410

Query: 633  GPPGLPGLKGDPGVPGLPGAKGEVGAD---GVPGFPGLPGREGIAGPQGPKGDRGSRGEK 689
            G PG  G +G  G  G PG  G +G     G PG  G PG++G+AGP+G  G+RG  G  
Sbjct: 411  GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 470

Query: 690  GDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-DGSVLSVPGPEGRPGFAGFPGPAGPKGNLG 748
            G  G +  G PG PG PG PG         D       GP G PG  G PGP GP+G  G
Sbjct: 471  GPKGAN--GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 528

Query: 749  SKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP 808
              G  G PGPKG  GEPG                  GE G  G PG  G PG  GE G  
Sbjct: 529  QPGVMGFPGPKGANGEPGK----------------AGEKGLPGAPGLRGLPGKDGETGAA 572

Query: 809  GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRP- 867
            G PG  G  G +GE+G PG +    G +G+PGPPGPPG  G PG    D  V  E+  P 
Sbjct: 573  GPPGPAGPAGERGEQGAPGPS----GFQGLPGPPGPPGEGGKPG----DQGVPGEAGAPG 624

Query: 868  -----------------------GPPGLPGNQGPPGPKGAKGEVGPP---GPPGQFPFDF 901
                                   GP GLPG  G  GPKGA G  GPP   GPPG      
Sbjct: 625  LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 684

Query: 902  LQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGP------RGYPGIPGP 955
             +  A + G KGDRGD G+KG  G PG  G  G  L GP GPPGP      +G  G PGP
Sbjct: 685  ERGAAGIAGPKGDRGDVGEKGPEGAPGKDG--GRGLTGPIGPPGPAGANGEKGEVGPPGP 742

Query: 956  KGES-------IRGQPGPPGP---QGPPGI----------GYEGRQGPPGPPGPPGPPSF 995
             G +        RG+ GPPGP    GPPG           G  G++G  G PGP GP   
Sbjct: 743  AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802

Query: 996  PGPHRQTISVPGPPGPPGPPGPPGTMG 1022
            PGP   T  V GP G  G  GPPG  G
Sbjct: 803  PGPQGPT-GVTGPKGARGAQGPPGATG 828



 Score =  518 bits (1334), Expect = e-146
 Identities = 331/766 (43%), Positives = 374/766 (48%), Gaps = 99/766 (12%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368
            G +  PG D ++   G    PG R    GL G KG  G PG PG  G PG+  L G PG 
Sbjct: 444  GNRGFPGQDGLA---GPKGAPGER-GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 499

Query: 369  PCPVSPLGPAG-PALQTVPGPQGP------------PGPPGRDGTPGRDGE---PGDPGE 412
              P   +GP+G P     PGP GP            PGP G +G PG+ GE   PG PG 
Sbjct: 500  AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL 559

Query: 413  DGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDME 472
             G PG  G  G  G PG  GP G++G+ G    GP G QG PGPPGP     K     + 
Sbjct: 560  RGLPGKDGETGAAGPPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGGKPGDQGVP 617

Query: 473  GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREGPP 531
            G      L   RG RGFPG  G PG  GL G  G  G   +D P G +G  G PG +GPP
Sbjct: 618  GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 677

Query: 532  GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA------PGPAGARGESGLA 585
            G  G+PG  G  G  GP G  G  G  G  GAPG  G +G       PGPAGA GE G  
Sbjct: 678  GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 737

Query: 586  GAPGPAGPPGP---------PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD----GPQ 632
            G PGPAG  G           GPPGP G   P G D   G+ G      +  D    GPQ
Sbjct: 738  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797

Query: 633  GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR---------EGIAGPQGPKGDR 683
            GP G PG +G  GV G  GA+G  G  G  GFPG  GR          G  GP GP G  
Sbjct: 798  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857

Query: 684  GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742
            G +G +GD G  G  G+PGL GP GPPG                G  G  G +G  GP G
Sbjct: 858  GPKGARGDSGPPGRAGEPGLQGPAGPPGE--------------KGEPGDDGPSGAEGPPG 903

Query: 743  PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 802
            P+G  G +G  G PG +GE+G PG +  P G    P ++GA G  G RGPPGP G PG  
Sbjct: 904  PQGLAGQRGIVGLPGQRGERGFPG-LPGPSGE---PGKQGAPGASGDRGPPGPVGPPGLT 959

Query: 803  GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862
            G  G PGR G PG +G  G  G  G      G RG  G  G PG PGPPG+P        
Sbjct: 960  GPAGEPGREGSPGADGPPGRDGAAGVK----GDRGETGAVGAPGAPGPPGSP-------- 1007

Query: 863  ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922
                 GP G  G QG  G  GA+G +GP GP G       Q      G +GD+G+AG+ G
Sbjct: 1008 -----GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ------GPRGDKGEAGEPG 1056

Query: 923  ERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQ 981
            ERG  G  GF G  L G PGPPGP G  G  GP G S  G  GPPGP GP G  G  G  
Sbjct: 1057 ERGLKGHRGFTG--LQGLPGPPGPSGDQGASGPAGPS--GPRGPPGPVGPSGKDGANGIP 1112

Query: 982  GPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
            GP GPPGP G     GP     + PGPPGPPGPPGP   M A +G+
Sbjct: 1113 GPIGPPGPRGRSGETGPAGPPGN-PGPPGPPGPPGPGIDMSAFAGL 1157



 Score =  404 bits (1037), Expect = e-112
 Identities = 280/742 (37%), Positives = 332/742 (44%), Gaps = 114/742 (15%)

Query: 246  GASGDSGS----GLGDARELLREE-----------TGAALKPRLPAPPPVT----TPPLA 286
            GA+GD G     GL  AR L               +GA  +   P PP        P + 
Sbjct: 474  GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 533

Query: 287  GGSSTEDSRSE--EVEEQTTVASLGAQTLPGSDS---VSTWDGSVRTPGGRVKEG--GLK 339
            G    + +  E  +  E+    + G + LPG D     +   G     G R ++G  G  
Sbjct: 534  GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 593

Query: 340  GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRD 398
            G +G PG PGPPG  G PG   +PG  G P  V P G  G P  +  PG QG  GP G  
Sbjct: 594  GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP 653

Query: 399  GTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD------VGPKGDKGDPGVGERGPPGPQG 452
            GTPG DG  G  G  G PG  GP G  G PG+       GPKGD+GD  VGE+GP G  G
Sbjct: 654  GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD--VGEKGPEGAPG 711

Query: 453  ---------PPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 503
                     P GPPGP+  + +   +   G           G RG  GPPGP G  G PG
Sbjct: 712  KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 771

Query: 504  EPGRFGVNSSD----------VPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTG 553
              G+ G                PGP G  G PG +GP G   + GP G  G +GPPG TG
Sbjct: 772  ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG---VTGPKGARGAQGPPGATG 828

Query: 554  QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDD 613
              G+ G  G PG  G+ G PGP G  G+ G  GA G +GPPG  G PG  GP  P G   
Sbjct: 829  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888

Query: 614  MEGSGGPFWSTARSADGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGF--- 664
              G  GP  S A    GPQG  G      LPG +G+ G PGLPG  GE G  G PG    
Sbjct: 889  EPGDDGP--SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD 946

Query: 665  ---------PGL------PGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGP 708
                     PGL      PGREG  G  GP G  G+ G KGD G+ G VG PG PGPPG 
Sbjct: 947  RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006

Query: 709  PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768
            PGP               G +G  G AG  GP GP G  G++G +G  GP+G+KGE G  
Sbjct: 1007 PGPA-----------GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE- 1054

Query: 769  FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828
                     P ++G KG  GF G  G  G PG  G+ G  G  G  G  G  G  G  G 
Sbjct: 1055 ---------PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1105

Query: 829  ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV 888
                 G  G+PGP GPPGP G  G    ++        PGPPG PG  GP     A   +
Sbjct: 1106 D----GANGIPGPIGPPGPRGRSG----ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGL 1157

Query: 889  GPPGPPGQFPFDFLQLEAEMKG 910
            G P   G  P  +++ +    G
Sbjct: 1158 G-PREKGPDPLQYMRADQAAGG 1178



 Score =  376 bits (966), Expect = e-104
 Identities = 251/624 (40%), Positives = 277/624 (44%), Gaps = 162/624 (25%)

Query: 522  PGVPGREGPPG-FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG 580
            PG  G++G PG    + GP GPPG +GP G  G +G  G+      KG KGAPGP G  G
Sbjct: 31   PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD------KGEKGAPGPRGRDG 84

Query: 581  ESGLAGAPGPAGPPGPPGPP------------------------------------GPPG 604
            E G  G PGP GPPGPPGPP                                    GPPG
Sbjct: 85   EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144

Query: 605  PG---LPAGFDDMEG----------------------------SGGPFWSTARSADGPQ- 632
            P     P GF    G                            +G P  +  R   GPQ 
Sbjct: 145  PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 204

Query: 633  -----GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRG 687
                 G PGLPG+KG  G PGL GAKGE GA GV G  G PG  G  GP GP+G  G RG
Sbjct: 205  ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 264

Query: 688  EKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN 746
              G  G  G  G  G PGP GPPGPV              GP G PGF G PG  G  G 
Sbjct: 265  RTGPAGAAGARGNDGQPGPAGPPGPV--------------GPAGGPGFPGAPGAKGEAGP 310

Query: 747  LGSKGERGSPGPKGEKGEPGS--------------IFSPDGGALGPAQKGAKGEPGFRGP 792
             G++G  G+ GP+GE G PGS              I    G A  P   GA G PG RGP
Sbjct: 311  TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370

Query: 793  PGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASL-----------GFGMRGMPGP 841
            PGP G  G  G  G  G PG  G  G +G KGEPG A               G RG PG 
Sbjct: 371  PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430

Query: 842  PGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP---PGPKGAKGEVGPPGPPGQFP 898
             GP GPPG  G P  +     +    GP G PG +GP    GPKGA G+ G PG PG   
Sbjct: 431  VGPIGPPGERGAP-GNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG--- 486

Query: 899  FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGI---PGP 955
               L     + G  GD G  G+ G  G PG  G      PGPPGP G RG PG+   PGP
Sbjct: 487  ---LPGARGLTGRPGDAGPQGKVGPSGAPGEDG-----RPGPPGPQGARGQPGVMGFPGP 538

Query: 956  KGES-------IRGQPGPPGPQGPPG-IGYEGRQGPPGPPGP---------PGPPSFPGP 998
            KG +        +G PG PG +G PG  G  G  GPPGP GP         PGP  F G 
Sbjct: 539  KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG- 597

Query: 999  HRQTISVPGPPGPPGPPGPPGTMG 1022
                  +PGPPGPPG  G PG  G
Sbjct: 598  ------LPGPPGPPGEGGKPGDQG 615



 Score =  372 bits (955), Expect = e-102
 Identities = 258/648 (39%), Positives = 293/648 (45%), Gaps = 105/648 (16%)

Query: 242  DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 301
            D   GA+G  G   G A E  R E GA         P    PP  GG   +     E   
Sbjct: 566  DGETGAAGPPGPA-GPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622

Query: 302  QTTVA------------SLGAQTL---------PGSDSVSTWDGSVRTPGGRVKEG--GL 338
               V             S GAQ L         PG+D      G    PG +   G  G+
Sbjct: 623  PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682

Query: 339  KGQKGEPGVPGPPG------RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 392
             G++G  G+ GP G        GP G+P   G  GL  P+ P GPAG       G +G  
Sbjct: 683  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG-----ANGEKGEV 737

Query: 393  GPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQ 451
            GPPG  G+ G  G PG+ GE G PG  G  G PG  G  G KG++G+ G  G+ G PGPQ
Sbjct: 738  GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797

Query: 452  GP---PGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGPPGVPGLPGE 504
            GP   PGP GP+           +G    +GF G    + GP G  G PGPPG PG  G+
Sbjct: 798  GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV-GPPGSNGNPGPPGPPGPSGK 856

Query: 505  PGRFGVNS-SDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563
             G  G    S  PG AG PG+ G  GPPG  G PG  GP G EGPPG  G  G  G  G 
Sbjct: 857  DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL 916

Query: 564  PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWS 623
            PG +G +G PG  G  GE G  GAPG +G  GPPGP GPPG   PAG    EGS G    
Sbjct: 917  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG---- 972

Query: 624  TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDR 683
                ADGP G  G  G+KGD         +GE GA G PG PG PG  G AGP G +GDR
Sbjct: 973  ----ADGPPGRDGAAGVKGD---------RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019

Query: 684  GSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742
            G  G +G  G  G  G  G+ GP GP G      E     L   G  G  G  G PGP G
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK--GHRGFTGLQGLPGPPG 1077

Query: 743  PKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK 802
            P G+ G+ G  G  GP+G  G  G    P G      + GA G PG  GPPGP GR G  
Sbjct: 1078 PSGDQGASGPAGPSGPRGPPGPVG----PSG------KDGANGIPGPIGPPGPRGRSGET 1127

Query: 803  GEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGP 850
            G  G PG P                            GPPGPPGPPGP
Sbjct: 1128 GPAGPPGNP----------------------------GPPGPPGPPGP 1147



 Score =  234 bits (598), Expect = 3e-61
 Identities = 164/461 (35%), Positives = 188/461 (40%), Gaps = 58/461 (12%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G  G +GS         R ETG       P P     PP A G         E  ++   
Sbjct: 738  GPPGPAGSAGARGAPGERGETGP------PGPAGFAGPPGADGQPGAKGEQGEAGQKGDA 791

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP 365
             + G Q   G+       G     G R    G +G  G  G PG  GR GPPGS   PGP
Sbjct: 792  GAPGPQGPSGAPGPQGPTGVTGPKGAR----GAQGPPGATGFPGAAGRVGPPGSNGNPGP 847

Query: 366  PGLPCPVSPLGPAG-------PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK--- 415
            PG P P    GP G       P     PG QGP GPPG  G PG DG  G  G  G    
Sbjct: 848  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907

Query: 416  ---------PGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDK 465
                     PG  G +GFPG PG  G  G +G PG  G+RGPPGP GPPG  GP+    +
Sbjct: 908  AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 967

Query: 466  LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----------- 514
                  +G         ++G RG  G  G PG PG PG PG  G                
Sbjct: 968  EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027

Query: 515  --VPGPAGLPGVPGREGP---------PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563
                GPAG  G+ G +GP         PG  GL G  G  G +G PG  G  G  G +G 
Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087

Query: 564  PGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP------PGPPGPPGPGLPAGFDDMEGS 617
             G  G +G PGP G  G+ G  G PGP GPPGP       GP GPPG   P G     G 
Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147

Query: 618  GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGA 658
            G    + A      +GP  L  ++ D    GL     EV A
Sbjct: 1148 GIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDA 1188



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 58/148 (39%), Positives = 74/148 (50%), Gaps = 20/148 (13%)

Query: 892  GPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPG 951
            G P       L + A ++ +  D    G KG++GEPG        + GP GPPGP+G  G
Sbjct: 5    GAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGD----IKDIVGPKGPPGPQGPAG 60

Query: 952  IPGPKGE-SIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTIS----- 1004
              GP+G+   +G+ G PGP+G  G  G  G  GPPGPPGPPGPP   G     ++     
Sbjct: 61   EQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDE 120

Query: 1005 ---------VPGPPGPPGPPGPPGTMGA 1023
                     + GP GP GP GPPG  GA
Sbjct: 121  KAGGAQLGVMQGPMGPMGPRGPPGPAGA 148


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  528 bits (1359), Expect = e-149
 Identities = 387/1039 (37%), Positives = 474/1039 (45%), Gaps = 161/1039 (15%)

Query: 66   LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 123
            +AY     A      R  FP  F +DFSLL  +R  P  + P +      SAQ +  LG+
Sbjct: 58   VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114

Query: 124  KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 181
            +L       + +  LY +  G  Q  +   FR L    G+W  +A++V G  V L VDC+
Sbjct: 115  ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168

Query: 182  EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 241
            +    PL RS+R +    G  +F A+    D + F+G + EL +    Q +   C  +E 
Sbjct: 169  KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKE- 225

Query: 242  DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 301
                                L  E G   +P+   P      P    S     +++E + 
Sbjct: 226  --------------------LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQS 265

Query: 302  QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGL---------KGQKGEPGVPGPPG 352
            Q      G +   G  +V      V  P G     GL          G  G+PG  GPPG
Sbjct: 266  QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325

Query: 353  RAGPPGSPCLPGPPGLPCPV-----SPLGPAGPAL------------QTVPGPQGPPGPP 395
            RAG PGS   PGPPG    +     S  G  GP +            Q     +GPPGP 
Sbjct: 326  RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385

Query: 396  GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPG 455
            G  G PG  G+PG PG  G+ GD GPQG  G  G  GP G  G  G    G  G +G PG
Sbjct: 386  GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG--RAGADGARGMPG 443

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
             PG   + D+         GF G L  L G +G  G  G  G+PG PGE G  G +    
Sbjct: 444  DPG--VKGDR---------GFDG-LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI- 490

Query: 516  PGPAGLPGVPGREG---PPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS--- 569
             GP GLPG  G  G   P G PG+PGPPG  G +GP G  G  G  GE G PG +G+   
Sbjct: 491  -GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 549

Query: 570  KGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626
            +G PGP GA    GE G  G PG  G PG  GPPG PG   P G    +G  GP      
Sbjct: 550  QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP------ 603

Query: 627  SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------------LPGREGIA 674
               GP G PG  G+KG  G+ GL G KGE G DG PGF G            +PG  G  
Sbjct: 604  --QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 661

Query: 675  GPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVSEQDGSV--LSVPGP 728
            GP+GPKG  G  G+ G PG    K  +G PGLPG PG  GP        GS+     PG 
Sbjct: 662  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP-------KGSLGFPGFPGA 714

Query: 729  EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG-------GALG-PAQ 780
             G  G  G  G +GP+G  G  G RG  GP+G  G+ G+  +  G       G  G P  
Sbjct: 715  SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774

Query: 781  KGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 834
            +G  G PG +GPPGP G+      PG +GE+GF G+ G PG  G+ G +G  G+     G
Sbjct: 775  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG-PMG 833

Query: 835  MRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPP 894
             RG PGPPGPPG  G PGT   +         PGPPG PG  GP G +G  GE G PG  
Sbjct: 834  ERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAGLRGFPGERGLPGTA 889

Query: 895  GQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIP 953
            G             +G  G  G AG  GERG  G GG  G    PGP GPPG  G  G+P
Sbjct: 890  GGPGLK------GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 943

Query: 954  GPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1005
            G KG       + ++G  G PGP GPPG+ G +G +G  G PG  G     G H      
Sbjct: 944  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH------ 997

Query: 1006 PGPPGPPGPPGPPGTMGAS 1024
             GPPGPPGP GP G  GA+
Sbjct: 998  -GPPGPPGPIGPVGQPGAA 1015



 Score =  523 bits (1346), Expect = e-148
 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 366
            GAQ LPG             PG  G   + G  G +G PG  GP G  GP G P +PGPP
Sbjct: 470  GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 517

Query: 367  GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 426
            G+     P GP G       GPQG PGPPG+ GTPG  G PG  G  G  G+ GPQG PG
Sbjct: 518  GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 572

Query: 427  TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 474
             PG  G  G  G PG        G +GP GPQGP G PGP           ++G      
Sbjct: 573  LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632

Query: 475  -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 512
                 GF GD+                 +   GP+G  GP G PG PGL GE G+ GV  
Sbjct: 633  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 690

Query: 513  SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 557
                   GLPG PGR+GP      PGFPG         L G  GP G  GP G  GQ+G 
Sbjct: 691  ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 744

Query: 558  LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 609
             G  G  G KG+ G  GP G  GE GL G  GP G PGP GPPGPPG    PG P     
Sbjct: 745  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 804

Query: 610  -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 646
             GF    G  GP                  R   GP GPPG  GL         KGDPG 
Sbjct: 805  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 864

Query: 647  PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 699
            PG PG  G  G  G PG  GLPG       +G  GP GP G  GS GE+G  G  G +G 
Sbjct: 865  PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 924

Query: 700  PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 745
            PG PGP GPPG      V  + G +    GP GR G     G PGPAGP         KG
Sbjct: 925  PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 980

Query: 746  NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 805
             +G  G++G+ G KGE G PG    P G    P   GA GEPG RGP G +G  G +G  
Sbjct: 981  EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039

Query: 806  GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862
            GF G PG  G+ GL    GEKGE GD     G  G PGPPGP GP GP G          
Sbjct: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1086

Query: 863  ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922
                 GPPG  GN GPPG KG  GE G PG         +Q E  +KG +G+RG+ G+ G
Sbjct: 1087 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1136

Query: 923  ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 971
            + GEPG  G  G +   GP G PGP G+PG PGP GE            RG+ G PG  G
Sbjct: 1137 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1196

Query: 972  PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1014
             PG    G  GPPGP G  GP   PG   +            I  PG      P GP G 
Sbjct: 1197 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254

Query: 1015 PGPPGTMGASSGV----RLWATRQA 1035
            PGP G  G    V    R  AT QA
Sbjct: 1255 PGPDGLRGLPGSVGQQGRPGATGQA 1279



 Score =  432 bits (1112), Expect = e-121
 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368
            GA    G+   S  DG    PG R    GL G +G  G PGP G  GPPG   LPG PG 
Sbjct: 746  GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 801

Query: 369  ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 409
                        P P   +GP G A +T P    G  GPPGPPG  G PG   ++G  GD
Sbjct: 802  RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 861

Query: 410  PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 468
            PG  G PG  GP G  G PG+ G  G  G PG+ G  GP GP GP G PG          
Sbjct: 862  PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 911

Query: 469  IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 518
             +   +G GG +    GP G PGP GPPG  G   +PGE G  G    D       +PGP
Sbjct: 912  -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 966

Query: 519  AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 566
            AG PGV            PG++G  G  G  GPPGPPG  GP G+ G  G+ GE GA G 
Sbjct: 967  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1026

Query: 567  KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 614
            +G  GA G  G RG +G      L G PGP+G  G      P GPPGPPGP  PAG +  
Sbjct: 1027 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1086

Query: 615  EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 674
            +G  GP         GP G  G PG  G PG+ G PG KG  G  G  G  G PG  G  
Sbjct: 1087 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144

Query: 675  GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734
            GP+GP GD G    KG+PG   VG PG PGPPG  GP      QDG+     G +G PG 
Sbjct: 1145 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1194

Query: 735  AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 781
             G PGP G   P G LG +G  GSPG       KG KG+PG+I +P      G  GPA K
Sbjct: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254

Query: 782  -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 822
                               GA G+ G  GP GP G PG +G+ G  G  G PG+ GL G 
Sbjct: 1255 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1314

Query: 823  KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 882
             GE G+     G RG+PGP G PG  G  G P     +       GPPGLPG  GP G K
Sbjct: 1315 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1366

Query: 883  GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 930
            GA G  GP            PGPPG+     L ++   K  +   G    + +   P GG
Sbjct: 1367 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1425

Query: 931  GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 973
                   PG PG  G     G      E I     P G Q  P
Sbjct: 1426 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1460



 Score =  380 bits (975), Expect = e-105
 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%)

Query: 263  REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 322
            R E G   K   P PP V  P  A G   E     E          G Q LPG+      
Sbjct: 802  RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858

Query: 323  DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371
             G    PG   K+G           GL G  G PG+ G  G +GPPG    PG  G    
Sbjct: 859  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918

Query: 372  VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 428
              P+GP G      PGPQGPPG  G  G PG  G  G  G DG  G  G   P G PG  
Sbjct: 919  GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973

Query: 429  GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 477
            G+ G KG+ GDPG        GE GPPGP GP GP   PG +    +      +G  G  
Sbjct: 974  GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1033

Query: 478  GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 537
            GD     G RGF GPPGP G+ GLPG  G  G  + DV GP G PG PG  GP G  G  
Sbjct: 1034 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1087

Query: 538  GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597
            GP GPPG  G  G  G+KG  GE+G+PG +G  G  GP G RGE G +G PG  GPPGP 
Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1147

Query: 598  GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 635
            GP                  PGPPG G P G D  +G  G    P    +    G  GPP
Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1207

Query: 636  GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 695
            G  G +G  G PG  G +G  GA G PG  G PG+ G  GP GP G  G  G +G PG  
Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1267

Query: 696  GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754
            G  G+PG  G  GPPGPV              GP G PG  G  G  G KG+ G  G  G
Sbjct: 1268 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1313

Query: 755  SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 805
             PG +GEKG+ G +  P G    P QKG  G PG  GP         PGP G  G KG  
Sbjct: 1314 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1369

Query: 806  GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 849
            G PG P        KGEK             G+ GPPG PGPPG
Sbjct: 1370 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1391


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  527 bits (1358), Expect = e-149
 Identities = 364/889 (40%), Positives = 418/889 (47%), Gaps = 149/889 (16%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G +G +G+   +  +  R ETG         P PV +P L G   T+ +           
Sbjct: 387  GEAGPTGARGPEGPQGQRGETGP--------PGPVGSPGLPGAIGTDGTP---------- 428

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSP 360
               GA+   GS   S   GS   PG    +G     G++GQ G+PGVPG  G AGP G P
Sbjct: 429  ---GAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEP 485

Query: 361  CLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419
               GP G+  P+ P G  G    +  PG  GPPGP G  G PG  G PG    DG PG  
Sbjct: 486  ---GPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGS---DGLPGPK 539

Query: 420  GPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS---- 474
            G QG  G  G  GPKG +GDPG  GE G PG +G  G PG      KL  +   G     
Sbjct: 540  GAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP 599

Query: 475  ---------GFGGDLEALRGPRGFPGPPGPPG------VPGLPGEPGRFG-VNSSDVPGP 518
                     G  G +  L GP+G  G PG PG      VPG  G PG+ G V  S   GP
Sbjct: 600  GPPGSIGIRGQPGSM-GLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP 658

Query: 519  AGLPGVPGREGPPG---FPGLPGPPGPPGR------EGPPGRTGQKGSLGEAGAPGHKGS 569
             GL G  G +GPPG   F GLPGPPGPPG       +G PG  G  G LG  G  G+ G 
Sbjct: 659  PGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGE 718

Query: 570  KGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAD 629
            +G PG  G  GE G+AG  GP GP G PGP G PG   P G   M G  G   +     D
Sbjct: 719  RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD 778

Query: 630  -------------------------GPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGF 664
                                     GP GP G  G KG+PG  GL G  G  G  G  G 
Sbjct: 779  RGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGE 838

Query: 665  PGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----VGQPGLPGPPGPPGPVVYVSEQDG 720
             G  G  G AGPQGP G  G +GE G+PG+ G     G  GL G PGP GP      + G
Sbjct: 839  NGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGG 898

Query: 721  -SVLSVPGPEGRPGFAGF---PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF-----SP 771
                  PG  G PG AG    PGPAG  G  G  GE G  GP G +G+PGS        P
Sbjct: 899  RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP 958

Query: 772  DGGALGPAQKGAKGE---PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828
             G   GP  KG  GE   PG  GPPGP G  G +G +G PG+ G  GM GL G  G PG 
Sbjct: 959  AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018

Query: 829  ASL--GFGMRGMPGP------------PGPPGPPGPPGTPVYDSNVFAESSR--PGPPGL 872
                   G +G PGP            PGP GP G  GTP  D  V     R  PGP GL
Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL 1078

Query: 873  PGNQGPPG---PKGAKGEVG---------PPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 920
            PG+QG PG   P GA G+ G         P GPPG+     L      +G +GD+GD G 
Sbjct: 1079 PGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP---GPQGPRGDKGDHGD 1135

Query: 921  KGERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEG 979
            +G+RG+ G  GF G   LPGPPGP G +G  GIPGP G       GPPGP GP      G
Sbjct: 1136 RGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPR-----GPPGPVGP-----SG 1185

Query: 980  RQGPPGPPGPPGPPSFPGPHRQT--ISVPGPPGPPGPPGPPGTMGASSG 1026
            ++G PGP GP GPP   G   +      PG PGPPGPPGPPG + A+ G
Sbjct: 1186 KEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALG 1234



 Score =  514 bits (1323), Expect = e-145
 Identities = 337/780 (43%), Positives = 376/780 (48%), Gaps = 143/780 (18%)

Query: 331  GRVKEGGLKGQKGEPGVPGPPGRAGP---PGSPCLPGPPGLPCPVSPLG---PAGPALQT 384
            GR+   G  GQ+G  G+PG PG  GP   PGS   PG PG+     P G   P GP  Q 
Sbjct: 345  GRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQR 404

Query: 385  ----VPGPQGPPGPPGR---DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGP---K 434
                 PGP G PG PG    DGTPG  G  G PG  G PG  GP G PG  G  GP   +
Sbjct: 405  GETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464

Query: 435  GDKGDPGV----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALR 484
            G  GDPGV          GE GP G QGP GPPG                      E  R
Sbjct: 465  GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGE---------------------EGKR 503

Query: 485  GPRGFPGPPGPPGVPGLPGEPGRFGVNSSD-VPGPAGLPGV---------PGREGPPGFP 534
            GPRG PG  GPPG  G  G PG  G   SD +PGP G  G           G +G PG P
Sbjct: 504  GPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRP 563

Query: 535  GLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPP 594
            G PG PG  G  G PG  G +G LG  GAPG  G  G PG  G RG+ G  G PGP G  
Sbjct: 564  GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623

Query: 595  GPPGPPGPPG-PGLPA--GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPG--- 648
            G PG PG  G  G+P   G    +G  GP         GP GPPGL G +G+ G PG   
Sbjct: 624  GDPGKPGEAGNAGVPGQRGAPGKDGEVGP--------SGPVGPPGLAGERGEQGPPGPTG 675

Query: 649  ---LPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPG 704
               LPG  G  G  G PG  G+PG  G  GP GP+G+RG+ GE+G+PG  G+ G+ G+ G
Sbjct: 676  FQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG 735

Query: 705  PPGPPGPVVYVSEQDGSVLSVPGPEGRPG---------------FAGFPGPAGPKGNLGS 749
              GP GP        GS    PGP G PG                AG PGP G +G +G 
Sbjct: 736  GHGPDGP-------KGS----PGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGE 784

Query: 750  KGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRG---PPGPYGRPGYKGE-- 804
            KG  G+ G  G +G PG +  P  G  GP   G KGEPG RG   PPG  G PG +GE  
Sbjct: 785  KGAEGTAGNDGARGLPGPLGPP--GPAGPT--GEKGEPGPRGLVGPPGSRGNPGSRGENG 840

Query: 805  ----IGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPG---PPGPPGPPGTPVYD 857
                +GF G  G  G  G+KGE GEPG      G  G PGP G    PGP GP G P   
Sbjct: 841  PTGAVGFAGPQGPDGQPGVKGEPGEPGQK----GDAGSPGPQGLAGSPGPHGPNGVPGLK 896

Query: 858  SNVFAESSRPGPPGLPGNQG---PPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 914
                 +   PG  G PG+ G   PPGP GA G  GP G PG+     L+ +    G  GD
Sbjct: 897  GGRGTQGP-PGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGD 955

Query: 915  RGDAGQKGERGEPGGGGFFGSSLPGPPGPPGP------RGYPGIPGPKGESIRGQPGPPG 968
            RG AG  G  G+ G  G  G   PGP GPPGP      RG  G+PG +GE  RG PG PG
Sbjct: 956  RGPAGPPGGPGDKGDPGEDGQ--PGPDGPPGPAGTTGQRGIVGMPGQRGE--RGMPGLPG 1011

Query: 969  PQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
            P G PG +G  G  G  GPPGP GPP   GP        G PGP GP G  GT G    V
Sbjct: 1012 PAGTPGKVGPTGATGDKGPPGPVGPPGSNGP-------VGEPGPEGPAGNDGTPGRDGAV 1064



 Score =  504 bits (1299), Expect = e-142
 Identities = 343/848 (40%), Positives = 390/848 (45%), Gaps = 130/848 (15%)

Query: 275  PAPPPVTTPPLA----GGSSTEDSRSEEVEEQT-----TVASLGAQTLPGSDSVSTWDGS 325
            P  PP    P+     GG +T   R  + ++        V  +  +  P     S     
Sbjct: 85   PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144

Query: 326  VRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP-------------- 371
             R P GR    G +G  GEPGVPG PG  GPPG P  PGP GL  P              
Sbjct: 145  ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204

Query: 372  ----------VSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGR---------DGEPGDPG 411
                      V P+GP GP  LQ   G  GP GPPG  G PG          +G PG PG
Sbjct: 205  GSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPG 264

Query: 412  EDGKPG------------DTGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPG 455
            EDG+PG              G +GFPG PG  G KG +G  G+    GE G PG +G  G
Sbjct: 265  EDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG 324

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
            P GP               G  G L    GPRG PG  G  G  G PG+ G  G+     
Sbjct: 325  PTGPM--------------GAMGPL----GPRGMPGERGRLGPQGAPGQRGAHGMPGK-- 364

Query: 516  PGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGP 575
            PGP G  G+PG  G PG PG+ G  GP G  GP G  GQ+G  G  G  G  G  GA G 
Sbjct: 365  PGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGT 424

Query: 576  AGARGESGLAGAPGPAGPPGPPGPPGPPGP----------GLPA--GFDDMEGSGGPFWS 623
             G  G  G  G+PG +GPPG  GPPG PGP          G P   G    +G  GP   
Sbjct: 425  DGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGE 484

Query: 624  TA-RSADGPQGPPGLPGL---KGDPGVPGLPGAKGEVGADGVPGFP---GLPGREGIAGP 676
                   GP GPPG  G    +GDPG  G PG  GE GA G  GFP   GLPG +G  G 
Sbjct: 485  PGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE 544

Query: 677  QGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAG 736
            +GP G  G +G +GDPG+   G+PGLPG  G  G    V   +G +    GP G PG  G
Sbjct: 545  RGPVGSSGPKGSQGDPGRP--GEPGLPGARGLTGN-PGVQGPEGKL----GPLGAPGEDG 597

Query: 737  FPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPY 796
             PGP G  G  G  G  G PGPKG  G+PG      G A  P Q+GA G+ G  GP GP 
Sbjct: 598  RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKP-GEAGNAGVPGQRGAPGKDGEVGPSGPV 656

Query: 797  GRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVY 856
            G PG  GE G  G PG  G  GL G  G PG+     G +G+PG PG  GP GP G    
Sbjct: 657  GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKP-GDQGVPGDPGAVGPLGPRG---- 711

Query: 857  DSNVFAESSRPGPPGLPGNQ------GPPGPKGAKGEVGPP---GPPGQFPFDFLQLEAE 907
            +     E   PG  GLPG +      GP GPKG+ G  G P   GPPG       +  A 
Sbjct: 712  ERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG 771

Query: 908  MKGEKGDRGDAGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKG----ESIRG 962
              G KGDRG  G+KG  G  G  G  G   P GPPGP GP G  G PGP+G       RG
Sbjct: 772  TPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831

Query: 963  QPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGP---PGPPGPPGPP 1018
             PG  G  GP G +G+ G QGP G PG  G P  PG  +     PGP    G PGP GP 
Sbjct: 832  NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG-QKGDAGSPGPQGLAGSPGPHGPN 890

Query: 1019 GTMGASSG 1026
            G  G   G
Sbjct: 891  GVPGLKGG 898



 Score =  503 bits (1296), Expect = e-142
 Identities = 343/845 (40%), Positives = 388/845 (45%), Gaps = 184/845 (21%)

Query: 283  PPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQK 342
            PP   G   E  R+    E     S GA+  PG+  +                 GLKG +
Sbjct: 259  PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP----------------GLKGHR 302

Query: 343  GEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPG 402
            G  G+ GP G  G PGS    GP G   P+  +GP GP  + +PG +G  GP G  G  G
Sbjct: 303  GHKGLEGPKGEVGAPGSKGEAGPTG---PMGAMGPLGP--RGMPGERGRLGPQGAPGQRG 357

Query: 403  RDGEPGDPGEDGKPGDTGPQGFPGTPG---DVGPKGDKGDPGV----GERGPPGPQGPPG 455
              G PG PG  G  G  G  GFPG PG   + GP G +G  G     GE GPPGP G PG
Sbjct: 358  AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPG 417

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD- 514
             PG          I  +G+         +GP G PG  GPPG  G PG PG  G      
Sbjct: 418  LPGA---------IGTDGT------PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQG 462

Query: 515  ---VPGPAGLPGVPGREGPPGFPG---LPGPPGPPGREGP------PGRTGQKGSLGEAG 562
                PG  G+PG  G  GP G PG   + GP GPPG EG       PG  G  G +GE G
Sbjct: 463  IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522

Query: 563  APGHKG---SKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPA-----GFDD 613
            APG++G   S G PGP GA+GE G  G+ GP G  G PG PG PG PG        G   
Sbjct: 523  APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582

Query: 614  MEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKG---------EVGADGVPGF 664
             EG  GP    A   DG  GPPG  G++G PG  GLPG KG         E G  GVPG 
Sbjct: 583  PEGKLGPLG--APGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640

Query: 665  PGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVL 723
             G PG++G  GP GP G  G  GE+G+ G  G  G  GLPGPPGPPG       + G   
Sbjct: 641  RGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPG-------EGGK-- 691

Query: 724  SVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI--FSPDGGALGPAQK 781
              PG +G PG  G  GP GP+G  G+ GERG PG  G  GE G      PDG    P   
Sbjct: 692  --PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP--- 746

Query: 782  GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGP 841
            G  G PG  GPPG  G PG +G  G PG  G  G  G KG +G  G+     G RG+PGP
Sbjct: 747  GPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGND----GARGLPGP 802

Query: 842  PGPPGPPGPPGTPVYDSNVFAESSRPGPPGL---------PGNQGPPGPKGAKGEVGPPG 892
             GPPGP GP G          E   PGP GL         PG++G  GP GA G  GP G
Sbjct: 803  LGPPGPAGPTG----------EKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852

Query: 893  PPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLP-------------- 938
            P GQ             G KG+ G+ GQKG+ G PG  G  GS  P              
Sbjct: 853  PDGQ------------PGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG 900

Query: 939  --GPPG------------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGP 983
              GPPG            PPGP G PG  GP GE   G+ GPPG +G PG  G  G +GP
Sbjct: 901  TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP--GKEGPPGLRGDPGSHGRVGDRGP 958

Query: 984  PGPPGPPGPPSFPGPHRQTISVPGPPGPPGP---------------------PGPPGTMG 1022
             GPPG PG    PG   Q    PGP GPPGP                     PG PG  G
Sbjct: 959  AGPPGGPGDKGDPGEDGQ----PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAG 1014

Query: 1023 ASSGV 1027
                V
Sbjct: 1015 TPGKV 1019



 Score =  390 bits (1002), Expect = e-108
 Identities = 261/638 (40%), Positives = 300/638 (47%), Gaps = 73/638 (11%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGE------------PGVPGPPGRAGP 356
            G   +PG       DG V  P G V   GL G++GE            PG PGPPG  G 
Sbjct: 633  GNAGVPGQRGAPGKDGEVG-PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK 691

Query: 357  PGSPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGK 415
            PG   +PG PG   P+ P G  G P  +  PG  G PG  G  G  G DG  G PG  G 
Sbjct: 692  PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751

Query: 416  PGDTGPQGFPGTPGD------VGPKGDKGDPGV----------GERGPPGPQGPPGPPGP 459
            PGDTGP G  G PG+       GPKGD+G  G           G RG PGP GPPGP GP
Sbjct: 752  PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811

Query: 460  SFRHDK---LTFIDMEGSGFGGDLEALRGPRG---FPGPPGPPGVPGLPGEPGRFGVNS- 512
            +    +      +   GS          GP G   F GP GP G PG+ GEPG  G    
Sbjct: 812  TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGD 871

Query: 513  SDVPGPAGLPGVPGREGPPGFPGLPG---PPGPPGREGPPGRTGQKGSLGEAGAPGHKGS 569
            +  PGP GL G PG  GP G PGL G     GPPG  G PG  G+ G  G AGAPG  G 
Sbjct: 872  AGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGP 931

Query: 570  KGAPG---PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626
             G PG   P G RG+ G  G  G  GP GPPG PG  G     G    +G  GP  +T +
Sbjct: 932  LGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQ 991

Query: 627  SA-------DGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGP 679
                      G +G PGLPG  G PG  G  GA G+ G  G  G PG  G  G  GP+GP
Sbjct: 992  RGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGP 1051

Query: 680  KGDRGS---------RGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSVP 726
             G+ G+         RG++GDPG  G+    G PG PGP G PG        D       
Sbjct: 1052 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAG--QRGDPGSRGPI 1109

Query: 727  GPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGP-AQKGAKG 785
            GP GR G  G PGP GP+G+ G  G+RG  G KG +G  G    P  G  GP  ++G+ G
Sbjct: 1110 GPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLP--GPPGPNGEQGSAG 1167

Query: 786  EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP 845
             PG  GP GP G  G  G+ G PG  G  G  G++G  GE G      G  G PGPPGPP
Sbjct: 1168 IPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPE----GPPGEPGPPGPP 1223

Query: 846  GPPGPPGTPVYDSNVFAESSRPGP-PGLPGNQGPPGPK 882
            GPPG     + D     + S P P P    +Q  P  K
Sbjct: 1224 GPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDK 1261



 Score =  373 bits (957), Expect = e-103
 Identities = 245/586 (41%), Positives = 279/586 (47%), Gaps = 83/586 (14%)

Query: 475  GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFP 534
            G  G +  + G RG PGP GPPG  G  GE G  G      PGP G  G+ G  G PG P
Sbjct: 116  GEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGR-----PGPRGPQGIDGEPGVPGQP 170

Query: 535  GLPGPPGPPGREGPPGRT----GQKGSLGEAGAPGHKGS--KGAPGPAGARGESGLAGAP 588
            G PGPPG P   GP G +     Q   L E    G +     G+ GP G RG  GL G  
Sbjct: 171  GAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQ 230

Query: 589  GPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPG 648
            G AGP GPPG PG PGP  P G                 + GP+GPPG PG  G+PG  G
Sbjct: 231  GGAGPTGPPGEPGDPGPMGPIG-----------------SRGPEGPPGKPGEDGEPGRNG 273

Query: 649  LPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGP 708
             PG  G  G+ G  GFPG PG  G+ G +G KG  G +GE G PG  G  + G  GP G 
Sbjct: 274  NPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKG--EAGPTGPMGA 331

Query: 709  PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768
             GP+              GP G PG  G  GP G  G  G+ G  G PGP G  G PGS 
Sbjct: 332  MGPL--------------GPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSS 377

Query: 769  FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828
              P      P  KG  G  G RGP GP G+   +GE G PG  G PG+ G  G  G PG 
Sbjct: 378  GFPGN----PGMKGEAGPTGARGPEGPQGQ---RGETGPPGPVGSPGLPGAIGTDGTPGA 430

Query: 829  ASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR--PGPPGLPGNQGPPGPKGAKG 886
                 G  G PG  GPPG  GPPG+P    +   +  R  PG PG+PG +G  GPKG  G
Sbjct: 431  K----GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPG 486

Query: 887  E---VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS-LPGPPG 942
                 GP GPPG+      + +   +G+ G  G  G  GERG PG  GF GS  LPGP G
Sbjct: 487  PHGIQGPIGPPGE------EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG 540

Query: 943  PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI----------GYEGRQGP---PGPPGP 989
              G RG  G  GPKG   +G PG PG  G PG           G EG+ GP   PG  G 
Sbjct: 541  AQGERGPVGSSGPKGS--QGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGR 598

Query: 990  PGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQA 1035
            PGPP   G   Q  S+ G PGP G  G PG  G +    +   R A
Sbjct: 599  PGPPGSIGIRGQPGSM-GLPGPKGSSGDPGKPGEAGNAGVPGQRGA 643



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 47/114 (41%), Positives = 55/114 (48%), Gaps = 14/114 (12%)

Query: 927  PGGGGF-FGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPG 985
            PGGG   FG       G  G +G PG+  P    IRG+PGP GP G  G    G +GP G
Sbjct: 100  PGGGNTNFGR------GRKGQKGEPGLV-PVVTGIRGRPGPAGPPGSQGP--RGERGPKG 150

Query: 986  PPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQ 1039
             PGP GP    G       VPG PG PGPPG P   G     R ++ + A L +
Sbjct: 151  RPGPRGPQGIDGEP----GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDE 200


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  524 bits (1350), Expect = e-148
 Identities = 393/1062 (37%), Positives = 482/1062 (45%), Gaps = 186/1062 (17%)

Query: 66   LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 123
            +AY     A      R  FP  F +DFSLL  +R  P  + P +      SAQ +  LG+
Sbjct: 58   VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114

Query: 124  KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 181
            +L       + +  LY +  G  Q  +   FR L    G+W  +A++V G  V L VDC+
Sbjct: 115  ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168

Query: 182  EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 241
            +    PL RS+R +    G  +F A+    D + F+G + EL +    Q +   C  +E 
Sbjct: 169  KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKE- 225

Query: 242  DDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE 301
                                L  E G   +P+   P      P    S     +++E + 
Sbjct: 226  --------------------LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQS 265

Query: 302  QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGV-------PGPPG 352
            Q           PG +     + S+  P      G  GLKG+KGEP V        GPPG
Sbjct: 266  QDPT--------PGEEE-EILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPG 316

Query: 353  RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT-VPGPQGPPGPPG-------RDGTPGRD 404
              GP G    PG  G P PV   G  GP  +  +PG  G PGPPG       R G+ G D
Sbjct: 317  PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD 376

Query: 405  GEP---------------------GDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVG 443
              P                     G PG  G  G  GP G PG+PG  G  GD     +G
Sbjct: 377  KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD-----LG 431

Query: 444  ERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPG----- 497
             +GP GPQG  GPPG + R  +      +G+ G  GD   ++G RGF G PG PG     
Sbjct: 432  PQGPRGPQGLTGPPGKAGRRGRA---GADGARGMPGD-PGVKGDRGFDGLPGLPGEKGHR 487

Query: 498  ----VPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREG---PPGFPGLPGPPGPPGREGPP 549
                  GLPG PG  G    D   GP GLPG  G  G   P G PG+PGPPG  G +GP 
Sbjct: 488  GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 547

Query: 550  GRTGQKGSLGEAGAPGHKGS---KGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPP 603
            G  G  G  GE G PG +G+   +G PGP GA    GE G  G PG  G PG  GPPG P
Sbjct: 548  GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607

Query: 604  GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 663
            G   P G    +G  GP         GP G PG  G+KG  G+ GL G KGE G DG PG
Sbjct: 608  GKEGPPGTKGNQGPSGP--------QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPG 659

Query: 664  FPG------------LPGREGIAGPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPG 707
            F G            +PG  G  GP+GPKG  G  G+ G PG    K  +G PGLPG PG
Sbjct: 660  FKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPG 719

Query: 708  PPGPVVYVSEQDGSV--LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEP 765
              GP        GS+     PG  G  G  G  G +GP+G  G  G RG  GP+G  G+ 
Sbjct: 720  RQGP-------KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772

Query: 766  GSIFSPDG-------GALG-PAQKGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRP 811
            G+  +  G       G  G P  +G  G PG +GPPGP G+      PG +GE+GF G+ 
Sbjct: 773  GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 832

Query: 812  GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPG 871
            G PG  G+ G +G  G+     G RG PGPPGPPG  G PGT   +         PGPPG
Sbjct: 833  GPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPG 887

Query: 872  LPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGG 931
             PG  GP G +G  GE G PG  G             +G  G  G AG  GERG  G GG
Sbjct: 888  APGKDGPAGLRGFPGERGLPGTAGGPGLK------GNEGPSGPPGPAGSPGERGAAGSGG 941

Query: 932  FFGS-SLPGPPGPPGPRGYPGIPGPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQG 982
              G    PGP GPPG  G  G+PG KG       + ++G  G PGP GPPG+ G +G +G
Sbjct: 942  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001

Query: 983  PPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1024
              G PG  G     G H       GPPGPPGP GP G  GA+
Sbjct: 1002 EVGDPGQKGTKGNKGEH-------GPPGPPGPIGPVGQPGAA 1036



 Score =  523 bits (1346), Expect = e-148
 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 366
            GAQ LPG             PG  G   + G  G +G PG  GP G  GP G P +PGPP
Sbjct: 491  GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 538

Query: 367  GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 426
            G+     P GP G       GPQG PGPPG+ GTPG  G PG  G  G  G+ GPQG PG
Sbjct: 539  GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 593

Query: 427  TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 474
             PG  G  G  G PG        G +GP GPQGP G PGP           ++G      
Sbjct: 594  LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653

Query: 475  -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 512
                 GF GD+                 +   GP+G  GP G PG PGL GE G+ GV  
Sbjct: 654  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 711

Query: 513  SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 557
                   GLPG PGR+GP      PGFPG         L G  GP G  GP G  GQ+G 
Sbjct: 712  ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 765

Query: 558  LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 609
             G  G  G KG+ G  GP G  GE GL G  GP G PGP GPPGPPG    PG P     
Sbjct: 766  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 825

Query: 610  -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 646
             GF    G  GP                  R   GP GPPG  GL         KGDPG 
Sbjct: 826  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 885

Query: 647  PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 699
            PG PG  G  G  G PG  GLPG       +G  GP GP G  GS GE+G  G  G +G 
Sbjct: 886  PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 945

Query: 700  PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 745
            PG PGP GPPG      V  + G +    GP GR G     G PGPAGP         KG
Sbjct: 946  PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001

Query: 746  NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 805
             +G  G++G+ G KGE G PG    P G    P   GA GEPG RGP G +G  G +G  
Sbjct: 1002 EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060

Query: 806  GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862
            GF G PG  G+ GL    GEKGE GD     G  G PGPPGP GP GP G          
Sbjct: 1061 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1107

Query: 863  ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922
                 GPPG  GN GPPG KG  GE G PG         +Q E  +KG +G+RG+ G+ G
Sbjct: 1108 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1157

Query: 923  ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 971
            + GEPG  G  G +   GP G PGP G+PG PGP GE            RG+ G PG  G
Sbjct: 1158 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1217

Query: 972  PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1014
             PG    G  GPPGP G  GP   PG   +            I  PG      P GP G 
Sbjct: 1218 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275

Query: 1015 PGPPGTMGASSGV----RLWATRQA 1035
            PGP G  G    V    R  AT QA
Sbjct: 1276 PGPDGLRGLPGSVGQQGRPGATGQA 1300



 Score =  432 bits (1112), Expect = e-121
 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368
            GA    G+   S  DG    PG R    GL G +G  G PGP G  GPPG   LPG PG 
Sbjct: 767  GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 822

Query: 369  ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 409
                        P P   +GP G A +T P    G  GPPGPPG  G PG   ++G  GD
Sbjct: 823  RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 882

Query: 410  PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 468
            PG  G PG  GP G  G PG+ G  G  G PG+ G  GP GP GP G PG          
Sbjct: 883  PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 932

Query: 469  IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 518
             +   +G GG +    GP G PGP GPPG  G   +PGE G  G    D       +PGP
Sbjct: 933  -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 987

Query: 519  AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 566
            AG PGV            PG++G  G  G  GPPGPPG  GP G+ G  G+ GE GA G 
Sbjct: 988  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1047

Query: 567  KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 614
            +G  GA G  G RG +G      L G PGP+G  G      P GPPGPPGP  PAG +  
Sbjct: 1048 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1107

Query: 615  EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 674
            +G  GP         GP G  G PG  G PG+ G PG KG  G  G  G  G PG  G  
Sbjct: 1108 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165

Query: 675  GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734
            GP+GP GD G    KG+PG   VG PG PGPPG  GP      QDG+     G +G PG 
Sbjct: 1166 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1215

Query: 735  AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 781
             G PGP G   P G LG +G  GSPG       KG KG+PG+I +P      G  GPA K
Sbjct: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275

Query: 782  -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 822
                               GA G+ G  GP GP G PG +G+ G  G  G PG+ GL G 
Sbjct: 1276 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1335

Query: 823  KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 882
             GE G+     G RG+PGP G PG  G  G P     +       GPPGLPG  GP G K
Sbjct: 1336 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1387

Query: 883  GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 930
            GA G  GP            PGPPG+     L ++   K  +   G    + +   P GG
Sbjct: 1388 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1446

Query: 931  GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 973
                   PG PG  G     G      E I     P G Q  P
Sbjct: 1447 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1481



 Score =  380 bits (975), Expect = e-105
 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%)

Query: 263  REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 322
            R E G   K   P PP V  P  A G   E     E          G Q LPG+      
Sbjct: 823  RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879

Query: 323  DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371
             G    PG   K+G           GL G  G PG+ G  G +GPPG    PG  G    
Sbjct: 880  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939

Query: 372  VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 428
              P+GP G      PGPQGPPG  G  G PG  G  G  G DG  G  G   P G PG  
Sbjct: 940  GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 994

Query: 429  GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 477
            G+ G KG+ GDPG        GE GPPGP GP GP   PG +    +      +G  G  
Sbjct: 995  GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1054

Query: 478  GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 537
            GD     G RGF GPPGP G+ GLPG  G  G  + DV GP G PG PG  GP G  G  
Sbjct: 1055 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1108

Query: 538  GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597
            GP GPPG  G  G  G+KG  GE+G+PG +G  G  GP G RGE G +G PG  GPPGP 
Sbjct: 1109 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1168

Query: 598  GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 635
            GP                  PGPPG G P G D  +G  G    P    +    G  GPP
Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1228

Query: 636  GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 695
            G  G +G  G PG  G +G  GA G PG  G PG+ G  GP GP G  G  G +G PG  
Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288

Query: 696  GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754
            G  G+PG  G  GPPGPV              GP G PG  G  G  G KG+ G  G  G
Sbjct: 1289 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1334

Query: 755  SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 805
             PG +GEKG+ G +  P G    P QKG  G PG  GP         PGP G  G KG  
Sbjct: 1335 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1390

Query: 806  GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 849
            G PG P        KGEK             G+ GPPG PGPPG
Sbjct: 1391 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1412


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  523 bits (1347), Expect = e-148
 Identities = 358/878 (40%), Positives = 414/878 (47%), Gaps = 159/878 (18%)

Query: 324  GSVRTPGGRVKEGGLKGQKGEPG----VPGPPGRAGPPGSPCLPGP------------PG 367
            G    PGG    G L G KGEPG    +PGPPG  G PGSP  PGP            PG
Sbjct: 618  GQAGFPGGPGSPG-LPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPG 676

Query: 368  LPCPVSPLG--------PAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGD 418
            LP     +G        P GP  +  +PG  GPPG PGR G  G  G PG  G+ G+PG 
Sbjct: 677  LPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV 736

Query: 419  -----TGPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPGPPGPSFRHDKLTFI 469
                  G  G PG PG  G KG  G PGV    G  GPPG QG  G PGP      +   
Sbjct: 737  GLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSP 796

Query: 470  DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGP----------- 518
             + G G  G     RGP G  GPPG  G PG+ GE G  G    D+PGP           
Sbjct: 797  GVPGIGPPG----ARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG 852

Query: 519  ----AGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574
                +GLPG+PG++G PG PG PG  G  G  G PG+ G  G +G  G PG KG  G PG
Sbjct: 853  ITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPG 912

Query: 575  PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS-------------GGPF 621
             +G RG+ GL G  G  G PG PG       G   G    +G              G P 
Sbjct: 913  SSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPG 972

Query: 622  WSTARSADGPQGPPGLPGLKGDPGV------PGLPGAKGEVGADGVPGFPGLPGREGIAG 675
                   DG  G PG PG KGDPG+      PGLPG KG VG  G+PG PG  G  GI G
Sbjct: 973  TPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPG 1032

Query: 676  PQGP---KGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSE-----QDGSVLSVPG 727
            PQG     GD+G++GEKG  G  G+G PGL G  G  G   +        + GS+  +PG
Sbjct: 1033 PQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSI-GIPG 1091

Query: 728  PEGRPGFAGFPGPAGPKGNLGSKGERGS---------PGPKGEKGEPGSIFSPDG--GAL 776
              G PG  G PG  G  G+ G  GE+G          PG KGE G PG+   P G  G  
Sbjct: 1092 MPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP-GPTGPAGQK 1150

Query: 777  G-------PAQKGAKGEP-----GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEK- 823
            G       P   G KGEP     GF G PG  G  G KGE+GFPG  G PG+ G KGE+ 
Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210

Query: 824  --------------GEPGDASLG----FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESS 865
                          G PG A+ G     G +G PG PG PGP GPPG P  D  V  +  
Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGID-GVKGDKG 1269

Query: 866  RPGPPGLPGNQGP---------------PGPKGAKGEVGPPGPPG-QFPFDFLQLEAEMK 909
             PG PG PG  GP               PG  G+KG++GPPG PG Q P     L+  +K
Sbjct: 1270 NPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQG-IK 1328

Query: 910  GEKGDRGDAGQKGERGEPGGGGFFG-----SSLPGPPGPPGPRGYPGIPGPKG-ESIRGQ 963
            G++GD+G  G KG  G PG  G +        LPGP GPPG +G  G+PGPKG + + G 
Sbjct: 1329 GDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGL 1388

Query: 964  PGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
             G PGP G PG  G  G++G  GP GP GP  FPGP       PGP G PG  GPPGT  
Sbjct: 1389 VGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGP-------PGPDGLPGSMGPPGTPS 1441

Query: 1023 ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1060
               G     TR +      + P G  I       LYV+
Sbjct: 1442 VDHG--FLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQ 1477



 Score =  491 bits (1264), Expect = e-138
 Identities = 340/851 (39%), Positives = 385/851 (45%), Gaps = 177/851 (20%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGS---PCLPGP 365
            G + LPG   V  + G ++ P G     G KG  GEPG+PG  G  GPPG+   P  PG 
Sbjct: 49   GERGLPGLQGVIGFPG-MQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGL 107

Query: 366  PGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT----- 419
            PG+P    P GP G P      G +GP GPPG  G  G  G PG PG  G PG+      
Sbjct: 108  PGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVP 167

Query: 420  -----GPQGFPGTPGDVGPKGDKGDPGV----GERGPPGPQGPPGPPGPSFRHDKLTFID 470
                 G +GFPG PG  GP G  G  G     G  GPPGP GPPGPPG            
Sbjct: 168  GMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG------------ 215

Query: 471  MEGSGFGGDLEALRGPRGFPGPPGPPGVPGL--------------------PGEPGRFGV 510
             E    G   +  +G +G  G  GPPGVPG                     PG  G  GV
Sbjct: 216  -EKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGV 274

Query: 511  NSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSK 570
                 PG  G  G PG++G  G  G PG PG PG  G  GR G +G  GEAG PG  G  
Sbjct: 275  GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334

Query: 571  GAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA-------GFDDMEGSGG 619
               GP G +GE G  G PGP G PGP G PG PG    PGLP        GF    G  G
Sbjct: 335  IGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKG 394

Query: 620  PFWSTARSADGPQGPPGLPGLKGDPGVPGLPG--------AKGEVGADGVPGFPGLPGRE 671
                   S  GP G  GLPG  G PG PG PG          G  G  G PG PG PG  
Sbjct: 395  DRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFI 454

Query: 672  GIAGPQGPKGD----------RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDG 720
            G  G +G KG+          RG  G +G PG+ G  GQPG  G  G PG       +DG
Sbjct: 455  GEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPG-------RDG 507

Query: 721  SVLSVPGPEGRPGF-------------------------AGFPGPAGPKGNLGSKGERGS 755
             V  VPGP+G PG                           GFPG  G  G  GS G  G 
Sbjct: 508  -VAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH 566

Query: 756  PGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGY--------KGEIGF 807
            PG  G KG PGS+     G  GP   G  G PG RG  GP G PGY        KG+ GF
Sbjct: 567  PGLPGPKGSPGSVGLK--GERGP--PGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGF 622

Query: 808  PGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRP 867
            PG PG PG+ G KGE G+        G  G+PG PG PGP G  G P            P
Sbjct: 623  PGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFP----------GTP 672

Query: 868  GPPGLPGNQ-----------GPPGPKGA---KGEVGPPGPPGQFPFDFLQLEAEMKGEKG 913
            G PGLPG +           GPPGPKG     G++GPPG PG+  F+ L     ++G+KG
Sbjct: 673  GRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKG 732

Query: 914  DRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG-------ESIRGQPGP 966
            + G  G  G +G PG  G     +PG PG  G  G PG+PG  G       + IRG+PGP
Sbjct: 733  EPG-VGLPGLKGLPGLPG-----IPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGP 786

Query: 967  P------GPQGPPGIGYEGRQGPPGPPGPP---GPPSFPG----PHRQTISVPGPPGPPG 1013
            P      G  G PGIG  G +GPPG  GPP   GPP   G    P    + +PGP G  G
Sbjct: 787  PGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG 846

Query: 1014 PPGPPGTMGAS 1024
              G PG  G S
Sbjct: 847  AQGLPGITGQS 857



 Score =  446 bits (1148), Expect = e-125
 Identities = 313/767 (40%), Positives = 353/767 (46%), Gaps = 160/767 (20%)

Query: 385  VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDV---GPKGDKGDPG 441
            V G +G  G PG  G  G  G  G  G  G PG  G  G PG PG     GP G  G PG
Sbjct: 44   VKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPG 103

Query: 442  -VGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVP 499
              G  G PG  GPPGPPG P     K         G  G L    G  GF G PGPPG+P
Sbjct: 104  NPGLPGIPGQDGPPGPPGIPGCNGTK---------GERGPL-GPPGLPGFAGNPGPPGLP 153

Query: 500  GLPGEPGRF--GVNSSDVPGPAGLPGVPGREGPPGFPGL---------PGPPGPPGREGP 548
            G+ G+PG     V    + G  G PG+PG  GPPG PGL          GPPGPPG  GP
Sbjct: 154  GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP 213

Query: 549  PGRTGQ-----------KGSLGEAGAPG--------HKGSKGAPGPAGARGESGLAGAP- 588
            PG  GQ           KG  G +G PG         KG     G  G +GE G  G P 
Sbjct: 214  PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG 273

Query: 589  -GPAGPPGPPGPPGPPG----------PGLPA--GFDDMEGSGGPFWSTARSADGPQGPP 635
             G  G PG PGP G PG          PG P   G+  + G  GP     +   GP GPP
Sbjct: 274  VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGP--QGEKGEAGPPGPP 331

Query: 636  GLP------GLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG--IAGPQGPKGDRGSRG 687
            G+       G KG+ G PG PG +GE G  G PG PG PG  G  + G  G  G  G RG
Sbjct: 332  GIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERG 391

Query: 688  EKGDPGKDGV------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP---------EGRP 732
            EKGD G  G       G+ GLPGPPG PGP       +G V   PGP          G+P
Sbjct: 392  EKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQP 451

Query: 733  GFAGF----------------------PGPAGPKGNL------GSKGERGSPGPKGEKGE 764
            GF G                       PGP GP G +      G+KG+RG PG  G  G 
Sbjct: 452  GFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGV 511

Query: 765  PGSIFSP----DGGALG-PAQ-------KGAKGEPGFRGPPGPYGR---PGYKGEIGFPG 809
            PG   +P      GA G P +       KG KG+PGF G PG  GR   PG  G  G PG
Sbjct: 512  PGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPG 571

Query: 810  RPGRPGMNGLKGEKGEPGDASLGF-GMRGMPGPPGPP--GPPGPPGTPVYDSNVFAESSR 866
              G PG  GLKGE+G PG   +GF G RG  GPPGPP  GP GP G          +  +
Sbjct: 572  PKGSPGSVGLKGERGPPG--GVGFPGSRGDTGPPGPPGYGPAGPIG----------DKGQ 619

Query: 867  PGPPGLPGNQGPPGPKGAKGEVGP-PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925
             G PG PG+ G PGPKG  G++ P PGPPG    + L       G +GDRG  G  G  G
Sbjct: 620  AGFPGGPGSPGLPGPKGEPGKIVPLPGPPGA---EGLPGSPGFPGPQGDRGFPGTPGRPG 676

Query: 926  EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG----------ESIRGQPGPPGPQGPPGI 975
             PG  G  G    G PGPPGP+G  G+PG  G            + G PG  G +G PG+
Sbjct: 677  LPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV 736

Query: 976  GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
            G  G +G PG PG PG P   G    +I VPG PG  G  GPPG  G
Sbjct: 737  GLPGLKGLPGLPGIPGTPGEKG----SIGVPGVPGEHGAIGPPGLQG 779



 Score =  324 bits (830), Expect = 4e-88
 Identities = 232/590 (39%), Positives = 259/590 (43%), Gaps = 156/590 (26%)

Query: 559  GEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDMEGS 617
            G+    G KG KG  G  G +G  G  G  GP GP GPPG  G  G PGLP      +G+
Sbjct: 37   GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPG----TKGT 92

Query: 618  GGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677
             GP    A    G  G PG+PG  G PG PG+PG  G  G  G  G PGLPG  G  GP 
Sbjct: 93   RGP--PGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPP 150

Query: 678  GPKGDRGSRGE----------KGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPG 727
            G  G +G  GE          KG+ G  G+  PG PGPPG PG              + G
Sbjct: 151  GLPGMKGDPGEILGHVPGMLLKGERGFPGI--PGTPGPPGLPG--------------LQG 194

Query: 728  PEGRPGFAGFPGPAGPKGNLGSKGERGSP--GPKGEKGEPGSIFSPDGGALGPAQ----- 780
            P G PGF G PGP GP G  G KG+ G    GPKG+KG+ G    P  G  G AQ     
Sbjct: 195  PVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPP--GVPGQAQVQEKG 252

Query: 781  -------KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-DASLG 832
                   KG KGEPGF+G PG     G KGE G PG  G+PG +G KGEKG PG     G
Sbjct: 253  DFATKGEKGQKGEPGFQGMPGV----GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPG 308

Query: 833  F-GMRGMPGPPGPPGPPGPPGTP--VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVG 889
            + G+ G  GP G  G  GPPG P  V  +    E    G PG PG +G PGPKG  G  G
Sbjct: 309  YPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPG 368

Query: 890  PPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP------PGP 943
             PGPPG  P              G  G  G  GERGE G  GF G+SLPGP      PGP
Sbjct: 369  QPGPPG-LPVP------------GQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGP 415

Query: 944  PGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-----------------------GYEGR 980
            PG  G PG PG     +  QPGPPG QGPPGI                         +G 
Sbjct: 416  PGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGY 475

Query: 981  QGPPGPPGPPGPPSFPG----------PHRQTIS-VPGPPGPPG---------------- 1013
            +GPPGP GPPG   FPG          P R  ++ VPGP G PG                
Sbjct: 476  RGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYF 535

Query: 1014 ------------------------------PPGPPGTMGASSGVRLWATR 1033
                                           PG PG  G+   V L   R
Sbjct: 536  DLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGER 585



 Score =  298 bits (762), Expect = 3e-80
 Identities = 194/479 (40%), Positives = 222/479 (46%), Gaps = 87/479 (18%)

Query: 244  SDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRS--EEVEE 301
            S G  GD G+         + E G A       PP +  P L G    +          E
Sbjct: 1036 SPGLPGDKGA---------KGEKGQA------GPPGIGIPGLRGEKGDQGIAGFPGSPGE 1080

Query: 302  QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPC 361
            +    S+G   +PGS  +    GSV  PG      GL G+KG+ G+PG  G  G  G   
Sbjct: 1081 KGEKGSIGIPGMPGSPGLKGSPGSVGYPG----SPGLPGEKGDKGLPGLDGIPGVKGEAG 1136

Query: 362  LPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGE--PGDPGEDGKPGDT 419
            LPG PG      P GPAG   +  PG  G PG  G  G PG  G   PG PG  G  G  
Sbjct: 1137 LPGTPG------PTGPAGQ--KGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK 1188

Query: 420  GPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGD 479
            G  GFPG  G  G  G KG+ G    GPPGPQG PG P                   G  
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGF--MGPPGPQGQPGLP-------------------GSP 1227

Query: 480  LEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGP 539
              A  GP+G  GP G PG+PGLPG  G         PG  G+ GV G +G PG+PG PG 
Sbjct: 1228 GHATEGPKGDRGPQGQPGLPGLPGPMG--------PPGLPGIDGVKGDKGNPGWPGAPGV 1279

Query: 540  PGP---------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP 590
            PGP         PG  G PG TG KG +G  G PG +G KG PG  G +G+ G  G PG 
Sbjct: 1280 PGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGA 1339

Query: 591  AGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLP 650
             G PGPPGPPGP        +D ++G  G          GP+GPPGL GL+G PG  G  
Sbjct: 1340 KGLPGPPGPPGP--------YDIIKGEPG--------LPGPEGPPGLKGLQGLPGPKGQQ 1383

Query: 651  GAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPP 709
            G  G VG  G PG PG  G  G  G  GP G  G RG  G PG DG+  PG  GPPG P
Sbjct: 1384 GVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL--PGSMGPPGTP 1440



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 61/199 (30%), Positives = 73/199 (36%), Gaps = 47/199 (23%)

Query: 245  DGASGDSGSGLGDARELLREETGAALKPRLPAP---PPVTTPPLAGGSSTEDSRSEEVEE 301
            DG  GD G+             G    P +P P   P     P  GGS        ++  
Sbjct: 1262 DGVKGDKGN------------PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP 1309

Query: 302  QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG---------LKGQKGEPGVPGPPG 352
                   G + LPG   +    G    PG +   G          +KG+ G PG  GPPG
Sbjct: 1310 PGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPG 1369

Query: 353  R------------------AGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGP 394
                                G PG P +PG  G P     +GPAGP      GP+G PGP
Sbjct: 1370 LKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPT-----GPRGFPGP 1424

Query: 395  PGRDGTPGRDGEPGDPGED 413
            PG DG PG  G PG P  D
Sbjct: 1425 PGPDGLPGSMGPPGTPSVD 1443


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  523 bits (1346), Expect = e-148
 Identities = 358/865 (41%), Positives = 397/865 (45%), Gaps = 193/865 (22%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 366
            GAQ LPG             PG  G   + G  G +G PG  GP G  GP G P +PGPP
Sbjct: 577  GAQGLPGP------------PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 624

Query: 367  GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPG 426
            G+     P GP G       GPQG PGPPG+ GTPG  G PG  G  G  G+ GPQG PG
Sbjct: 625  GVRGMDGPQGPKGSL-----GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 679

Query: 427  TPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS----- 474
             PG  G  G  G PG        G +GP GPQGP G PGP           ++G      
Sbjct: 680  LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739

Query: 475  -----GFGGDL-----------------EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 512
                 GF GD+                 +   GP+G  GP G PG PGL GE G+ GV  
Sbjct: 740  EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV-- 797

Query: 513  SDVPGPAGLPGVPGREGP------PGFPG---------LPGPPGPPGREGPPGRTGQKGS 557
                   GLPG PGR+GP      PGFPG         L G  GP G  GP G  GQ+G 
Sbjct: 798  ------PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 851

Query: 558  LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPA---- 609
             G  G  G KG+ G  GP G  GE GL G  GP G PGP GPPGPPG    PG P     
Sbjct: 852  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 911

Query: 610  -GFDDMEGSGGPFWSTA-------------RSADGPQGPPGLPGL---------KGDPGV 646
             GF    G  GP                  R   GP GPPG  GL         KGDPG 
Sbjct: 912  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 971

Query: 647  PGLPGAKGEVGADGVPGFPGLPGR------EGIAGPQGPKGDRGSRGEKGDPGKDG-VGQ 699
            PG PG  G  G  G PG  GLPG       +G  GP GP G  GS GE+G  G  G +G 
Sbjct: 972  PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGP 1031

Query: 700  PGLPGPPGPPGPVVY--VSEQDGSVLSVPGPEGRPGF---AGFPGPAGP---------KG 745
            PG PGP GPPG      V  + G +    GP GR G     G PGPAGP         KG
Sbjct: 1032 PGRPGPQGPPGAAGEKGVPGEKGPI----GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1087

Query: 746  NLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEI 805
             +G  G++G+ G KGE G PG    P G    P   GA GEPG RGP G +G  G +G  
Sbjct: 1088 EVGDPGQKGTKGNKGEHGPPGPP-GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1146

Query: 806  GFPGRPGRPGMNGL---KGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFA 862
            GF G PG  G+ GL    GEKGE GD     G  G PGPPGP GP GP G          
Sbjct: 1147 GFNGPPGPIGLQGLPGPSGEKGETGDV----GPMGPPGPPGPRGPAGPNGA--------- 1193

Query: 863  ESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG 922
                 GPPG  GN GPPG KG  GE G PG         +Q E  +KG +G+RG+ G+ G
Sbjct: 1194 -DGPQGPPGGVGNLGPPGEKGEPGESGSPG---------IQGEPGVKGPRGERGEKGESG 1243

Query: 923  ERGEPGGGGFFG-SSLPGPPGPPGPRGYPGIPGPKGES----------IRGQPGPPGPQG 971
            + GEPG  G  G +   GP G PGP G+PG PGP GE            RG+ G PG  G
Sbjct: 1244 QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1303

Query: 972  PPGIGYEGRQGPPGPPGPPGPPSFPGPHRQ-----------TISVPG------PPGPPGP 1014
             PG    G  GPPGP G  GP   PG   +            I  PG      P GP G 
Sbjct: 1304 SPGP--TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361

Query: 1015 PGPPGTMGASSGV----RLWATRQA 1035
            PGP G  G    V    R  AT QA
Sbjct: 1362 PGPDGLRGLPGSVGQQGRPGATGQA 1386



 Score =  497 bits (1280), Expect = e-140
 Identities = 393/1112 (35%), Positives = 481/1112 (43%), Gaps = 199/1112 (17%)

Query: 66   LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIR--PATEGPGVLFAITDSAQAMVLLGV 123
            +AY     A      R  FP  F +DFSLL  +R  P  + P +      SAQ +  LG+
Sbjct: 58   VAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLY---SAQGVRQLGL 114

Query: 124  KLSGVQDGHQDISLLYTEP-GAGQTHTAASFR-LPAFVGQWTHLALSVAGGFVALYVDCE 181
            +L       + +  LY +  G  Q  +   FR L    G+W  +A++V G  V L VDC+
Sbjct: 115  ELG------RPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCK 168

Query: 182  EFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEG 241
            +    PL RS+R +    G  +F A+    D + F+G + EL +    Q +   C  +E 
Sbjct: 169  KRVTRPLPRSARPVLDTHGVIIFGARI--LDEEVFEGDVQELAIVPGVQAAYESCEQKEL 226

Query: 242  DDSDG-ASGDSGSGLGDARELLREETGAALKPRLPAP-------------PP----VTTP 283
            +   G            A+   +++     +P+   P             PP    +TT 
Sbjct: 227  ECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTG 286

Query: 284  PLAGGSSTEDSRSEEVEEQTTVASL-----GAQTLPGSDSVST---WDGSVRTPGGRVK- 334
                         EE+ E + +  L       Q  P +D        +G    P G    
Sbjct: 287  TTPDYQDPTPGEEEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDY 346

Query: 335  EGGLKGQKGEPGVPGPP-------GRAGPPGSPCLPGPPGLPC----------PVSPLGP 377
              G      E    GP          A   G   L G  G P           P  P GP
Sbjct: 347  TYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP 406

Query: 378  AG----PALQTVPGPQGPP---GPPGRDGTPGRDGEPGDPGED----------------- 413
            AG    P +Q  PGP G P   GPPGR G PG DG PG PG                   
Sbjct: 407  AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 466

Query: 414  --------------------GKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQG 452
                                G PG  G  G PG  G  G  G KG+ G +G +GP GPQG
Sbjct: 467  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526

Query: 453  PPGPPGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPP---------GVPGLP 502
              GPPG + R  +      +G+ G  GD   ++G RGF G PG P         G  GLP
Sbjct: 527  LTGPPGKAGRRGR---AGADGARGMPGD-PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 582

Query: 503  GEPGRFGVNSSDVP-GPAGLPGVPGRE---GPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558
            G PG  G    D   GP GLPG  G     GP G PG+PGPPG  G +GP G  G  G  
Sbjct: 583  GPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQ 642

Query: 559  GEAGAPGHK---GSKGAPGPAGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFD 612
            GE G PG +   G++G PGP GA    GE G  G PG  G PG  GPPG PG   P G  
Sbjct: 643  GEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 702

Query: 613  DMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP------- 665
              +G  GP         GP G PG  G+KG  G+ GL G KGE G DG PGF        
Sbjct: 703  GNQGPSGP--------QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKG 754

Query: 666  -----GLPGREGIAGPQGPKGDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVS 716
                 G+PG  G  GP+GPKG  G  G+ G PG    K  +G PGLPG PG  GP     
Sbjct: 755  DRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP----- 809

Query: 717  EQDGSV--LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS------- 767
               GS+     PG  G  G  G  G +GP+G  G  G RG  GP+G  G+ G+       
Sbjct: 810  --KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 867

Query: 768  -IFSPDGGALGPAQKGAKGEPGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLK 820
                P G    P  +G  G PG +GPPGP G+      PG +GE+GF G+ G PG  G+ 
Sbjct: 868  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 927

Query: 821  GEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPG 880
            G +G  G+     G RG PGPPGPPG  G PGT   +         PGPPG PG  GP G
Sbjct: 928  GPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAG 982

Query: 881  PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-SSLPG 939
             +G  GE G PG  G             +G  G  G AG  GERG  G GG  G    PG
Sbjct: 983  LRGFPGERGLPGTAGGPGL------KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036

Query: 940  PPGPPGPRGYPGIPGPKG-------ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPG 991
            P GPPG  G  G+PG KG       + ++G  G PGP GPPG+ G +G +G  G PG  G
Sbjct: 1037 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1096

Query: 992  PPSFPGPHRQTISVPGPPGPPGPPGPPGTMGA 1023
                 G H      PGPPGP GP G PG  GA
Sbjct: 1097 TKGNKGEH----GPPGPPGPIGPVGQPGAAGA 1124



 Score =  491 bits (1264), Expect = e-138
 Identities = 341/853 (39%), Positives = 400/853 (46%), Gaps = 131/853 (15%)

Query: 239  EEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEE 298
            E G D      D   G GD     REET   L P L A    T    A        + E+
Sbjct: 334  EGGTDPPEGPYDYTYGYGDD---YREET--ELGPALSAE---TAHSGAAAHGPRGLKGEK 385

Query: 299  VEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPG 358
             E       +  +  PG +  +   G +  PG +    G  G  G+PG  GPPGRAG PG
Sbjct: 386  GEPAVLEPGMLVEGPPGPEGPA---GLIGPPGIQ----GNPGPVGDPGERGPPGRAGLPG 438

Query: 359  SPCLPGPPGLPCPV-----SPLGPAGPAL------------QTVPGPQGPPGPPGRDGTP 401
            S   PGPPG    +     S  G  GP +            Q     +GPPGP G  G P
Sbjct: 439  SDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRP 498

Query: 402  GRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSF 461
            G  G+PG PG  G+ GD GPQG  G  G  GP G  G  G    G  G +G PG PG   
Sbjct: 499  GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG--RAGADGARGMPGDPG--V 554

Query: 462  RHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGL 521
            + D+         GF G L  L G +G  G  G  G+PG PGE G  G +     GP GL
Sbjct: 555  KGDR---------GFDG-LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI--GPRGL 602

Query: 522  PGVPGREG---PPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGS---KGAPGP 575
            PG  G  G   P G PG+PGPPG  G +GP G  G  G  GE G PG +G+   +G PGP
Sbjct: 603  PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 662

Query: 576  AGA---RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 632
             GA    GE G  G PG  G PG  GPPG PG   P G    +G  GP         GP 
Sbjct: 663  QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP--------QGPL 714

Query: 633  GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------------LPGREGIAGPQGPK 680
            G PG  G+KG  G+ GL G KGE G DG PGF G            +PG  G  GP+GPK
Sbjct: 715  GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPK 774

Query: 681  GDRGSRGEKGDPG----KDGVGQPGLPGPPGPPGPVVYVSEQDGSV--LSVPGPEGRPGF 734
            G  G  G+ G PG    K  +G PGLPG PG  GP        GS+     PG  G  G 
Sbjct: 775  GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP-------KGSLGFPGFPGASGEKGA 827

Query: 735  AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG-------GALG-PAQKGAKGE 786
             G  G +GP+G  G  G RG  GP+G  G+ G+  +  G       G  G P  +G  G 
Sbjct: 828  RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 887

Query: 787  PGFRGPPGPYGR------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 840
            PG +GPPGP G+      PG +GE+GF G+ G PG  G+ G +G  G+     G RG PG
Sbjct: 888  PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPG 946

Query: 841  PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900
            PPGPPG  G PGT   +         PGPPG PG  GP G +G  GE G PG  G     
Sbjct: 947  PPGPPGEQGLPGTAGKEGT----KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 1002

Query: 901  FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPGPKG-- 957
                    +G  G  G AG  GERG  G GG  G    PGP GPPG  G  G+PG KG  
Sbjct: 1003 ------GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI 1056

Query: 958  -----ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGP 1011
                 + ++G  G PGP GPPG+ G +G +G  G PG  G     G H       GPPGP
Sbjct: 1057 GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH-------GPPGP 1109

Query: 1012 PGPPGPPGTMGAS 1024
            PGP GP G  GA+
Sbjct: 1110 PGPIGPVGQPGAA 1122



 Score =  489 bits (1258), Expect = e-138
 Identities = 323/767 (42%), Positives = 366/767 (47%), Gaps = 125/767 (16%)

Query: 338  LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVP----------- 386
            L+G  G  G  G PG  G PGSP L G  G    + P GP GP   T P           
Sbjct: 485  LRGPPGPMGYTGRPGPLGQPGSPGLKGESG---DLGPQGPRGPQGLTGPPGKAGRRGRAG 541

Query: 387  --GPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 442
              G +G PG PG  G  G DG PG PGE G  GDTG QG PG PG+ G +GD G+ G   
Sbjct: 542  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 601

Query: 443  -----GERGPPGPQGPPGPPGPSFRHDKLTFIDMEG-SGFGGDLEALRGPRGFPGPPGPP 496
                 G RG  GP+GPPG PGP           M+G  G  G L    GP+G PGPPG  
Sbjct: 602  LPGESGPRGLLGPKGPPGIPGPPGVRG------MDGPQGPKGSL----GPQGEPGPPGQQ 651

Query: 497  GVPG---LPGEPGRFGVNSSDVP-GPAGLPGVPGREGPPGFPGLPGPPGPPGREGP---- 548
            G PG   LPG  G  G +    P G  GLPG+PG +GPPG PG  GPPG  G +GP    
Sbjct: 652  GTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ 711

Query: 549  -----PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 603
                 PG  G KG  G  G  GHKG KG  G  G +G+ G+ G  G  G PG  G  GP 
Sbjct: 712  GPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 771

Query: 604  GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG 663
            GP         +G  GP         G  GPPGL G KG  GVPGLPG  G  G  G  G
Sbjct: 772  GP---------KGRTGP--------TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 814

Query: 664  FPGLPG------------REGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPGPPGPPG 710
            FPG PG            + G  G +GP G RG RG +G  GK G  G  G  GP GPPG
Sbjct: 815  FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPG 874

Query: 711  PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN---LGSKGERGSPGPKGEKGEPG- 766
                          +PGP+G  GF G  GP GP G     G  G+RG  G +G+ G PG 
Sbjct: 875  E-----------RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 923

Query: 767  -SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG---------M 816
              +  P G A      G +G PG  GPPG  G PG  G+ G  G PG PG         +
Sbjct: 924  PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 983

Query: 817  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876
             G  GE+G PG A  G G++G  GP GPPGP G PG    +          GPPG PG Q
Sbjct: 984  RGFPGERGLPGTAG-GPGLKGNEGPSGPPGPAGSPG----ERGAAGSGGPIGPPGRPGPQ 1038

Query: 877  GPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936
            GPPG  G KG  G  GP G    D +Q    + G  G  G AG+ G++GE G  G  G+ 
Sbjct: 1039 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTK 1098

Query: 937  ----LPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPG 991
                  GPPGPPGP G  G PG  G    G+PG  GPQG  G  G EG +G  GPPGP G
Sbjct: 1099 GNKGEHGPPGPPGPIGPVGQPGAAGAD--GEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1156

Query: 992  PPSFPGPHRQT--------ISVPGPPGP---PGPPGPPGTMGASSGV 1027
                PGP  +         +  PGPPGP    GP G  G  G   GV
Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1203



 Score =  432 bits (1112), Expect = e-121
 Identities = 306/763 (40%), Positives = 350/763 (45%), Gaps = 146/763 (19%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368
            GA    G+   S  DG    PG R    GL G +G  G PGP G  GPPG   LPG PG 
Sbjct: 853  GATGKSGAKGTSGGDGPHGPPGER----GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQ 908

Query: 369  ------------PCPVSPLGPAGPALQTVP----GPQGPPGPPGRDGTPG---RDGEPGD 409
                        P P   +GP G A +T P    G  GPPGPPG  G PG   ++G  GD
Sbjct: 909  RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 968

Query: 410  PGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTF 468
            PG  G PG  GP G  G PG+ G  G  G PG+ G  GP GP GP G PG          
Sbjct: 969  PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---------- 1018

Query: 469  IDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSSD-------VPGP 518
             +   +G GG +    GP G PGP GPPG  G   +PGE G  G    D       +PGP
Sbjct: 1019 -ERGAAGSGGPI----GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 1073

Query: 519  AGLPGV------------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGH 566
            AG PGV            PG++G  G  G  GPPGPPG  GP G+ G  G+ GE GA G 
Sbjct: 1074 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP 1133

Query: 567  KGSKGAPGPAGARGESG------LAGAPGPAGPPG------PPGPPGPPGPGLPAGFDDM 614
            +G  GA G  G RG +G      L G PGP+G  G      P GPPGPPGP  PAG +  
Sbjct: 1134 QGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1193

Query: 615  EGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIA 674
            +G  GP         GP G  G PG  G PG+ G PG KG  G  G  G  G PG  G  
Sbjct: 1194 DGPQGPPGGVGNL--GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1251

Query: 675  GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734
            GP+GP GD G    KG+PG   VG PG PGPPG  GP      QDG+     G +G PG 
Sbjct: 1252 GPKGPTGDDGP---KGNPGP--VGFPGDPGPPGEGGP----RGQDGAK-GDRGEDGEPGQ 1301

Query: 735  AGFPGPAG---PKGNLGSKGERGSPGP------KGEKGEPGSIFSPDG----GALGPAQK 781
             G PGP G   P G LG +G  GSPG       KG KG+PG+I +P      G  GPA K
Sbjct: 1302 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361

Query: 782  -------------------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 822
                               GA G+ G  GP GP G PG +G+ G  G  G PG+ GL G 
Sbjct: 1362 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP 1421

Query: 823  KGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPK 882
             GE G+     G RG+PGP G PG  G  G P     +       GPPGLPG  GP G K
Sbjct: 1422 PGEQGEK----GDRGLPGPQGSPGQKGEMGIPGASGPI----GPGGPPGLPGPAGPKGAK 1473

Query: 883  GAKGEVGP------------PGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 930
            GA G  GP            PGPPG+     L ++   K  +   G    + +   P GG
Sbjct: 1474 GATGPGGPKGEKGVQGPPGHPGPPGEV-IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGG 1532

Query: 931  GFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPP 973
                   PG PG  G     G      E I     P G Q  P
Sbjct: 1533 A------PGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSP 1567



 Score =  380 bits (975), Expect = e-105
 Identities = 264/644 (40%), Positives = 293/644 (45%), Gaps = 111/644 (17%)

Query: 263  REETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTW 322
            R E G   K   P PP V  P  A G   E     E          G Q LPG+      
Sbjct: 909  RGEVGFQGKTGPPGPPGVVGPQGAAG---ETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965

Query: 323  DGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371
             G    PG   K+G           GL G  G PG+ G  G +GPPG    PG  G    
Sbjct: 966  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025

Query: 372  VSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG---PQGFPGTP 428
              P+GP G      PGPQGPPG  G  G PG  G  G  G DG  G  G   P G PG  
Sbjct: 1026 GGPIGPPGR-----PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 1080

Query: 429  GDVGPKGDKGDPGV-------GERGPPGPQGPPGP---PGPSFRHDKLTFIDMEGS-GFG 477
            G+ G KG+ GDPG        GE GPPGP GP GP   PG +    +      +G  G  
Sbjct: 1081 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1140

Query: 478  GDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP 537
            GD     G RGF GPPGP G+ GLPG  G  G  + DV GP G PG PG  GP G  G  
Sbjct: 1141 GD----EGTRGFNGPPGPIGLQGLPGPSGEKG-ETGDV-GPMGPPGPPGPRGPAGPNGAD 1194

Query: 538  GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597
            GP GPPG  G  G  G+KG  GE+G+PG +G  G  GP G RGE G +G PG  GPPGP 
Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1254

Query: 598  GP------------------PGPPGPGLPAGFDDMEGSGG----PFWSTARSADGPQGPP 635
            GP                  PGPPG G P G D  +G  G    P    +    G  GPP
Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP 1314

Query: 636  GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKD 695
            G  G +G  G PG  G +G  GA G PG  G PG+ G  GP GP G  G  G +G PG  
Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1374

Query: 696  GV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERG 754
            G  G+PG  G  GPPGPV              GP G PG  G  G  G KG+ G  G  G
Sbjct: 1375 GQQGRPGATGQAGPPGPV--------------GPPGLPGLRGDAGAKGEKGHPGLIGLIG 1420

Query: 755  SPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP---------PGPYGRPGYKGEI 805
             PG +GEKG+ G +  P G    P QKG  G PG  GP         PGP G  G KG  
Sbjct: 1421 PPGEQGEKGDRG-LPGPQGS---PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1476

Query: 806  GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPG 849
            G PG P        KGEK             G+ GPPG PGPPG
Sbjct: 1477 G-PGGP--------KGEK-------------GVQGPPGHPGPPG 1498


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  514 bits (1325), Expect = e-145
 Identities = 345/830 (41%), Positives = 398/830 (47%), Gaps = 127/830 (15%)

Query: 275  PAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVK 334
            P PP    PP   G   +   S     +     +    + G       DG    PG +  
Sbjct: 529  PGPPGAEGPP---GLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPG-QPG 584

Query: 335  EGGLKGQKGEPGVPGPPG--RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPP 392
              G  G  GE G PGPPG      PG    PGP G P    P+GP G      PG +G P
Sbjct: 585  SHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHP 644

Query: 393  GPPGRDGTPGRDGEPGDPGEDGK-----PGDTGPQGFPGTPGDVGPKGDKGDPGV----G 443
            G PG  G  G DG  G  G+        PG  GP GF G PG  G  G +G PG+    G
Sbjct: 645  GVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDG 704

Query: 444  ERGPPGPQGP---PGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG 500
             +G PG  G    PGPPG  FR D      M   GFGG+  +   P G PGPPG PGV G
Sbjct: 705  HKGRPGTPGTAEIPGPPG--FRGD------MGDPGFGGEKGS--SPVGPPGPPGSPGVNG 754

Query: 501  LPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP------GREGPPGRTGQ 554
              G PG         PG  GL GVPG +GP G PG PG  GP       G +GP GR G 
Sbjct: 755  QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGH 814

Query: 555  KGSLGEAGAPGH---KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGL 607
             G  G  G PGH   +G+ G PG  G  G  G  GAPG  G PG  GPPGP G    PGL
Sbjct: 815  AGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGL 874

Query: 608  PA-----GFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662
            P      G   + G  GPF       DG  GPPG  G +G PG PG PG +G+ GA+G P
Sbjct: 875  PGRPGAHGPPGLPGIPGPF-----GDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929

Query: 663  GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----VGQPGLPGPPGPPGPVVYVSEQ 718
            G  G PG +G++G  G +G RG++G  G PG +G    + Q G PG PGPPG   +  E+
Sbjct: 930  GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989

Query: 719  DGSVLSVPGPEGR---------PGF----------AGFPGPAGPKGNLGSKGERGSPGPK 759
                   PG +GR         PGF           G PGP GP G+ G +G  G PG  
Sbjct: 990  GDK--GTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLP 1047

Query: 760  GEKGEPGSI----FSPDGGALGPAQKGAKGEPGFR-GPPGPYGRPGYKGEIGFPGRPGRP 814
            G++GEPGS     FS   GA GP  KG KG+P    GPPGP      KGE   PG PG P
Sbjct: 1048 GDQGEPGSPGPPGFSGIDGARGP--KGNKGDPASHFGPPGP------KGE---PGSPGCP 1096

Query: 815  GMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPG 874
            G  G  GE+G PG      G RG PG PGPPG  GPPG P        +   PG  G PG
Sbjct: 1097 GHFGASGEQGLPGIQ----GPRGSPGRPGPPGSSGPPGCP-------GDHGMPGLRGQPG 1145

Query: 875  NQGPPGPKGAKGEVGPPGPPG-QFPFDFLQLEA--EMKGEKGDRGDA------------- 918
              G PGP+G +G+ G PGPPG + P     L     +KG+KG +G +             
Sbjct: 1146 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGI 1205

Query: 919  -GQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRG-----QPGPPGPQGP 972
             G KGERG+PG  G       G  GPPGP G  G PGP G + R       PGPPG QGP
Sbjct: 1206 PGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGP 1265

Query: 973  PGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
            P  G +G +G PGPPG PG             +PGPPGPPGPPGPPG  G
Sbjct: 1266 P--GPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKG 1313



 Score =  512 bits (1318), Expect = e-144
 Identities = 357/877 (40%), Positives = 408/877 (46%), Gaps = 153/877 (17%)

Query: 267  GAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSV 326
            GA   P LP     + PP   G+  +   S     +      G    PG       DG  
Sbjct: 533  GAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHA 592

Query: 327  RTPGGRVKEG----GLKGQKGEPGVPGPPGRAGPPGSPCL--PGPPG------LPCPVSP 374
               G     G       G KG PG  GPPG+AGP G P L  PGPPG      +P     
Sbjct: 593  GEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGV 652

Query: 375  LGPAGPALQ---------TVPGPQGPPG---PPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 422
             GP G   Q         T PG  GPPG   PPG  G PG  G PG  G DG  G  G  
Sbjct: 653  RGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTP 712

Query: 423  GFPGTPGDVGPKGDKGDPGVG-ERG--PPGPQGPPGPPG----------PSFRHDKLTFI 469
            G    PG  G +GD GDPG G E+G  P GP GPPG PG          P+F H     +
Sbjct: 713  GTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGH-----L 767

Query: 470  DMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPG--- 526
               G      +  ++GPRG PG PG  G  G+PG  G  G    +  G AG PGVPG   
Sbjct: 768  GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGRE--GHAGFPGVPGPPG 825

Query: 527  ---REGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG 583
                 G PG PG PG PG PG  G PG  GQ G +G  G  G KG  G PG  GA G  G
Sbjct: 826  HSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPG 885

Query: 584  LAGAPGPAGPPGPPGPPGPPGP-GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKG 642
            L G PGP G  G PGPPGP GP GLP GF    G  G     A    G +G PG  G+ G
Sbjct: 886  LPGIPGPFGDDGLPGPPGPKGPRGLP-GFPGFPGERGK--PGAEGCPGAKGEPGEKGMSG 942

Query: 643  DPGVPGLPGAKGEVGADG------------VPGFPGLPGREGIAGPQGPKGDRGSRGEKG 690
             PG  GL GAKG +G  G             PG PG PG +G  G +G KG  G +G +G
Sbjct: 943  LPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRG 1002

Query: 691  DPGKDGV--------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAG 742
            +PG+ G         G+ G PGPPGPPGP              PG  G  GF GFPG  G
Sbjct: 1003 EPGRYGPPGFHRGEPGEKGQPGPPGPPGP--------------PGSTGLRGFIGFPGLPG 1048

Query: 743  PKGNLGSKGERG------SPGPKGEKGEPGSIFSPDG-----GALG-PAQKGAKGE---P 787
             +G  GS G  G      + GPKG KG+P S F P G     G+ G P   GA GE   P
Sbjct: 1049 DQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLP 1108

Query: 788  GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGP 847
            G +GP G  GRPG  G  G PG PG  GM GL+G+ GE GD     G++G PG PGPPG 
Sbjct: 1109 GIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR-GLQGDPGIPGPPGI 1167

Query: 848  PGPPGTPVYDSNVFAESSRPGPPGLPG--NQGPPGP---KGAKGEVGPPGPPGQFPFDFL 902
             GP G+P  +  +     + G  G  G  + GPPGP    G KGE G PG PG  P    
Sbjct: 1168 KGPSGSPGLNG-LHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISP---- 1222

Query: 903  QLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS---LP--------GPPGPPGPRGYPG 951
                   G +G +G  G  G  G PG  G  G +   +P        GPPGP GPRG PG
Sbjct: 1223 ------PGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPG 1276

Query: 952  IPGPKGE-----------SIRGQPGPPGPQGPPGI-------GYEGRQGPPGPPGPPGPP 993
             PG  G             + G PGPPGP GPPG        G +G++GP G PGP GP 
Sbjct: 1277 PPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPH 1336

Query: 994  SFPGPHRQTISVPGPPG---PPGPPGPPGTMGASSGV 1027
             FPGP  +   +PGPPG   P G PGP G  G  + V
Sbjct: 1337 GFPGPPGEK-GLPGPPGRKGPTGLPGPRGEPGPPADV 1372



 Score =  491 bits (1265), Expect = e-138
 Identities = 352/876 (40%), Positives = 396/876 (45%), Gaps = 176/876 (20%)

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGS------ 359
            A+ G +  PG        G V  PG  +   G  G++G PGVPG PG  GP G       
Sbjct: 607  ATPGGKGFPGPLGPPGKAGPVGPPG--LGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGD 664

Query: 360  --------PCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG 411
                    P   GPPG   P  P G  GP  Q  PG  G  G  GR GTPG    PG PG
Sbjct: 665  TISCNVTYPGRHGPPGFDGPPGPKGFPGP--QGAPGLSGSDGHKGRPGTPGTAEIPGPPG 722

Query: 412  EDGKPGD-----------TGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPS 460
              G  GD            GP G PG+PG  G KG  GDP  G  GPPG +G  G PG  
Sbjct: 723  FRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIK 782

Query: 461  FRHDKLTFIDMEG-SGFGGDLEALRGPRG------FPGPPGPPG------VPGLPGEPGR 507
                       EG +G  G L  L+GP+G      FPG PGPPG       PG+PG+PG 
Sbjct: 783  GPRGDPGCPGAEGPAGIPGFL-GLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGL 841

Query: 508  FGVNSS-----------DV--PGPAG------LPGVPGREGPPGFPGLPGP------PGP 542
             G   S           DV  PGPAG      LPG PG  GPPG PG+PGP      PGP
Sbjct: 842  PGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGP 901

Query: 543  PGREGP------PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 596
            PG +GP      PG  G++G  G  G PG KG  G  G +G  G+ GL GA G  GPPG 
Sbjct: 902  PGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGD 961

Query: 597  PGP---------PGPPGPGLPAGFDDMEGSGG-PFWSTARSADGPQGPPGL----PGLKG 642
             G          PG PGP    GF    G  G P     R   G  GPPG     PG KG
Sbjct: 962  EGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKG 1021

Query: 643  DPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG------DRGSRGEKGDPGKDG 696
             PG PG PG  G  G  G  GFPGLPG +G  G  GP G       RG +G KGDP    
Sbjct: 1022 QPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASH- 1080

Query: 697  VGQPGLPGPPGPPG-PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGN--------- 746
             G PG  G PG PG P  + +  +  +  + GP G PG  G PG +GP G          
Sbjct: 1081 FGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGL 1140

Query: 747  LGSKGERGSPGPKGEKGEPGSIFSPDGGALGPA-------------QKGAKGEPGFR--G 791
             G  GE G PGP+G +G+PG    P  G  GP+             QKG KG  G    G
Sbjct: 1141 RGQPGEMGDPGPRGLQGDPGIPGPP--GIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVG 1198

Query: 792  PPGPYGRPGYKGEIGFPGRPG--RPGMNGLKGEKGEPGDA-------SLGFGMRGMP--G 840
            PPGP G PG KGE G PG PG   PG  G KG  G PG +       + G   + +P  G
Sbjct: 1199 PPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPG 1258

Query: 841  PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGN----QGPPGPKGAKGEVGPPGPPGQ 896
            PPG  GPPGP G              PGPPGLPG+    +G PG  G  G  GPPGPPG 
Sbjct: 1259 PPGDQGPPGPDGP----------RGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGP 1308

Query: 897  FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP---GIP 953
              +          G+KG  G  G +G  G PG  G  G  LPGPPG  GP G P   G P
Sbjct: 1309 PGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKG--LPGPPGRKGPTGLPGPRGEP 1366

Query: 954  GPKGE-----SIRGQPGPPGPQGPPGI------------------GYEGRQGPPGPPGPP 990
            GP  +      I G PG PG +GP G                   G +GR+G  G PG P
Sbjct: 1367 GPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSP 1426

Query: 991  GPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1026
            GPP   G   +    PG PGPPGP G PG  G   G
Sbjct: 1427 GPPGRKGDTGED-GYPGGPGPPGPIGDPGPKGFGPG 1461



 Score =  466 bits (1199), Expect = e-131
 Identities = 378/1011 (37%), Positives = 433/1011 (42%), Gaps = 279/1011 (27%)

Query: 265  ETGAALKPRLPAPP----PVTTPPLAGGSSTEDSRSEE-----VEEQTTVASLGAQTLPG 315
            E G+   P  P P     P+  P   G S  +  R +        ++      G    PG
Sbjct: 60   EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPG 119

Query: 316  SDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP-------- 365
             D +    G    PG R K G  G  G +G+PG PG  G  GP G    PG         
Sbjct: 120  LDGIPGHPGP---PGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSV 176

Query: 366  ------------------PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEP 407
                              PGLP      GPAGP     PG  G  GPPG+ G PG  G P
Sbjct: 177  FILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPT--GYPGEPGLVGPPGQPGRPGLKGNP 234

Query: 408  G--------DPGEDGKPGDTGP------------------QGFPGTPGDVGPKGDKGDPG 441
            G        DPGE G+ G  GP                  +G PG  G  GP G KG+ G
Sbjct: 235  GVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG 294

Query: 442  VGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS-GFGGD--LEALRGPRGFPGP---PGP 495
            +G +G  G  G PGP G    +    F  ++G  G  GD  L  L GP+G PG    PGP
Sbjct: 295  IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354

Query: 496  PGV-----------PGLPGEPGRFGVNSSDV--PGPAGLPGVPGRE--------GPPGFP 534
            PGV           PG PG PGR+G  + DV  PGP GL G PG          GP GFP
Sbjct: 355  PGVLVTPPLPLKGPPGDPGFPGRYG-ETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFP 413

Query: 535  GLPGPPGP---PGR-EGPPGRTGQKGSLGEAGAPGHKG---------SKGAPGPAGARGE 581
            GLPG PG    PGR +  PG+ G+ GS G  GAPG +G         S G PGP G +G+
Sbjct: 414  GLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGK 473

Query: 582  SGLAGAPGPAGP----------PGPPGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSADG 630
             G  G  GP G           PGP GPPGPPG PG      D+   G P W   +   G
Sbjct: 474  VGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDL---GLPGWLGTKGDPG 530

Query: 631  P---QGPPGLPGLKGDPGVPGLPGAKGEV------------GADGVPGFPGLPGREGIAG 675
            P   +GPPGLPG  G  G PG  GAKG++            G DG PGFPG PG  G  G
Sbjct: 531  PPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDG 590

Query: 676  PQGPKGDRGSRGEK--------------GDPGKDG-VGQPGL--PGPPGPPG-------P 711
              G KGD G  G+               G PGK G VG PGL  PGPPG  G       P
Sbjct: 591  HAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHP 650

Query: 712  VVY----VSEQDGSVLSV----PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKG 763
             V     +  Q G  +S     PG  G PGF G PGP G  G  G+ G  GS G KG  G
Sbjct: 651  GVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPG 710

Query: 764  EPGSIFSPDGGALGPAQKGAKGEPGFRG--------PPGPYGRPGYKGEIGFPGRP---- 811
             PG+   P      P  +G  G+PGF G        PPGP G PG  G+ G PG P    
Sbjct: 711  TPGTAEIPGP----PGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGH 766

Query: 812  -------GRPGMNGLKGEKGEPGDASL-------GF----GMRGMPGPPGPPGPPGPPGT 853
                   G  G+ G+KG +G+PG           GF    G +G  G  G PG PGPPG 
Sbjct: 767  LGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGH 826

Query: 854  PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKG 913
               +        +PG PG PG+ G PG KG  G+VGPPGP G            MKG  G
Sbjct: 827  SC-ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAG------------MKGLPG 873

Query: 914  DRGDAGQKGERGEPGGGGFFGSS-LPGPPGPPGPRGYPGIPGPKGESIRGQPGP---PGP 969
              G  G  G  G PG  G FG   LPGPPGP GPRG PG PG  GE  RG+PG    PG 
Sbjct: 874  LPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGE--RGKPGAEGCPGA 931

Query: 970  QGPPG-------------------IGYEG---------RQGPPGPPGPPGPPSFPGP--- 998
            +G PG                   IG  G         ++G PG PGPPG   FPG    
Sbjct: 932  KGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGD 991

Query: 999  ---------------------HRQTISVPGPPGPPGPPGPPGTMGASSGVR 1028
                                 HR     PG  G PGPPGPPG  G S+G+R
Sbjct: 992  KGTPGMQGRRGEPGRYGPPGFHR---GEPGEKGQPGPPGPPGPPG-STGLR 1038



 Score =  407 bits (1047), Expect = e-113
 Identities = 287/720 (39%), Positives = 332/720 (46%), Gaps = 148/720 (20%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSPCLP 363
            GA  +PG   +  + GS   PGG+ + G     G  G KG PG+PG PG  GPPG P +P
Sbjct: 831  GAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIP 890

Query: 364  GP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 420
            GP    GLP P  P GP G  L   PG  G  G PG +G PG  GEPG+ G  G PGD  
Sbjct: 891  GPFGDDGLPGPPGPKGPRG--LPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGD-- 946

Query: 421  PQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGS---- 474
             +G  G  G +GP GD+G+  +  ++G PG  GPPG  G P  R DK T   M+G     
Sbjct: 947  -RGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGT-PGMQGRRGEP 1004

Query: 475  ---GFGGDLEALRGPRGFPGPPGPPGVPG---------LPGEPGRFGVNSSDVPGPAGLP 522
               G  G      G +G PGPPGPPG PG          PG PG  G   S  PGP G  
Sbjct: 1005 GRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGS--PGPPGFS 1062

Query: 523  GVPGREGPPGFPGLP----GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGA 578
            G+ G  GP G  G P    GPPGP G  G PG  G  G+ GE G PG +G +G+PG  G 
Sbjct: 1063 GIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP 1122

Query: 579  RGESG------------LAGAPGPAGPPGP------PGPPGPPG-------PGLPAGFDD 613
             G SG            L G PG  G PGP      PG PGPPG       PGL  G   
Sbjct: 1123 PGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLN-GLHG 1181

Query: 614  MEGSGGPFWSTARSADGPQGPPGLPGLK---GDPGVPGL--PGAKGEVGADGVPGFPGLP 668
            ++G  G   ++     GP GP G+PGLK   GDPG PG+  PG +G+ G  G PG  G P
Sbjct: 1182 LKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPP 1241

Query: 669  GREGIA-------------GPQGPKGDRGSRGEKGDPGKDG-----------VGQPGLPG 704
            G  G               G QGP G  G RG  G PG  G            G PG PG
Sbjct: 1242 GPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPG 1301

Query: 705  PPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGE 764
            PPGPPGP  Y            G +G+ G  GFPGP GP G  G  GE+G PGP G KG 
Sbjct: 1302 PPGPPGPPGY-----KGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKG- 1355

Query: 765  PGSIFSPDGGALGPAQ-------KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMN 817
            P  +  P G    PA         G  G PG RGP G  G PG +G  G PG  G PG++
Sbjct: 1356 PTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLD 1414

Query: 818  GLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG 877
            G +             G+ G+PG PGPPG  G  G          E   PG PG PG  G
Sbjct: 1415 GRR-------------GVDGVPGSPGPPGRKGDTG----------EDGYPGGPGPPGPIG 1451

Query: 878  PPGPKG-AKGEVG----------------PPGPPGQFP-FDFLQLEAEMKGEKGDRGDAG 919
             PGPKG   G +G                P G P  +  +  L LE + K    D G AG
Sbjct: 1452 DPGPKGFGPGYLGGFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAG 1511



 Score =  301 bits (770), Expect = 4e-81
 Identities = 212/507 (41%), Positives = 236/507 (46%), Gaps = 83/507 (16%)

Query: 574  GPAGARG--------ESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTA 625
            GP G R         E G  G PGP GP GP GP G PGP   +G   M G  GP  +  
Sbjct: 45   GPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG 104

Query: 626  RSAD-GPQGPPGLPGLKGDPGVPGLPGAKGEVGA---DGVPGFPGLPGREGIAGPQGPKG 681
               D GP G PG PGL G PG PG PG +G+ G    +G  G PG PG  G  GP GP G
Sbjct: 105  DKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLG 164

Query: 682  DRGSRGEKGDP--------GKDGV-GQPGLPGPPG------PPGPVVYVSEQDGSVLSVP 726
              G +GEKG+         G  G  G PGLPG PG      P GP  Y  E    ++  P
Sbjct: 165  HPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEP--GLVGPP 222

Query: 727  GPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGS--IFSPDGGALGPAQKGAK 784
            G  GRPG  G PG       +G KG+ G PG  G++G PG   +  P    L   +KG K
Sbjct: 223  GQPGRPGLKGNPG-------VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIK 275

Query: 785  GEPGFRGPPGPYGR--------------PGYKGEIGFPGRPGRPGMNGLKGEKGEPGDAS 830
            G PG  G PGP GR              PG+ G  G PG  G PG  GLKGE G  GD  
Sbjct: 276  GIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPG 335

Query: 831  LGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGP-PGLPGNQGPPGPKGAKGEVG 889
            L FG+ G  G PG  G PGPPG  V         + P P  G PG+ G PG  G  G+VG
Sbjct: 336  L-FGLIGPKGDPGNRGHPGPPGVLV---------TPPLPLKGPPGDPGFPGRYGETGDVG 385

Query: 890  PPGPPGQFPFDFLQLEAEM-KGEKGDRGDAGQKGERGEPGGGGFFG--SSLPGPPGPPGP 946
            PPGPPG      L    E   G  G  G  G  G  G PG  G  G   S PG PG PG 
Sbjct: 386  PPGPPG-----LLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGS 440

Query: 947  RGYPGIPG----PKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQT 1002
             G PG PG    P    I    G PGPQG      +G+ GPPG  GP G     G     
Sbjct: 441  PGLPGAPGLQGLPGSSVIYCSVGNPGPQG-----IKGKVGPPGGRGPKGEKGNEG---LC 492

Query: 1003 ISVPGPPGPPGPPGPPGTMGASSGVRL 1029
               PGP GPPGPPG PG  G+   + L
Sbjct: 493  ACEPGPMGPPGPPGLPGRQGSKGDLGL 519



 Score =  191 bits (486), Expect = 3e-48
 Identities = 145/357 (40%), Positives = 163/357 (45%), Gaps = 53/357 (14%)

Query: 714  YVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG 773
            Y+    G   SV       G  G PGP GP+G +G  G  G  G  GEKG  G    P G
Sbjct: 43   YIGPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGD-RGPPG 101

Query: 774  GALGPAQKGAKGEPGF---------RGPPGPYGRPGYKGEIGFPGRPGRPGMNGL----- 819
             A     KG  G PGF          GPPGP G+PG  G  G  G PG PG  G      
Sbjct: 102  AAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGG 161

Query: 820  ----KGEKGEPGDASLGFG-MRGMPGPPGPPGPPGPPGT-----PVYDSNVFAESSRPGP 869
                 GEKGE G++    G ++G+ G  G PG PG PG+     P   +    E    GP
Sbjct: 162  PLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGP 221

Query: 870  PGLPGNQGPPGPK--GAKGEVGPPGPPGQ--FPFDFLQLEAE----MKGEKGDRGDAGQK 921
            PG PG  G  G    G KG++G PG  GQ   P   L +E       KGEKG +G  G  
Sbjct: 222  PGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMV 281

Query: 922  GERGEPGGGGFFG---------SSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQG 971
            G  G PG  G  G            PGP G PG  G PG PG KGE  + G PG  G  G
Sbjct: 282  GLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIG 341

Query: 972  PPG-IGYEGRQGPPG----PP----GPPGPPSFPGPHRQTISVPGPPGPPGPPGPPG 1019
            P G  G  G  GPPG    PP    GPPG P FPG + +T  V GPPGPPG  G PG
Sbjct: 342  PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDV-GPPGPPGLLGRPG 397



 Score =  122 bits (307), Expect = 2e-27
 Identities = 87/223 (39%), Positives = 96/223 (43%), Gaps = 29/223 (13%)

Query: 238  DEEGDDSDGASGDSGS-GLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRS 296
            D+     DG  G  G  GL  + +LLR E G    P  P PP    PP            
Sbjct: 1262 DQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPP------------ 1309

Query: 297  EEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGP 356
                        G +  PG D      G V  PG +    G  G  GE G+PGPPGR GP
Sbjct: 1310 ------------GYKGFPGCDGKDGQKGPVGFPGPQGPH-GFPGPPGEKGLPGPPGRKGP 1356

Query: 357  PGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKP 416
             G P   G PG P  V    P  P L   PG +GP G  G  G  G  G PG  GE G  
Sbjct: 1357 TGLPGPRGEPGPPADVDDC-PRIPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLD 1414

Query: 417  GDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG 458
            G  G  G PG+PG  G KGD G+ G  G  GPPGP G PGP G
Sbjct: 1415 GRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG 1457


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  514 bits (1325), Expect = e-145
 Identities = 344/829 (41%), Positives = 401/829 (48%), Gaps = 114/829 (13%)

Query: 283  PPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQK 342
            PP   G + E      +  + +    G   + G D      G+V  PG      G +G  
Sbjct: 588  PPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPG-EPGPPGQQGNH 646

Query: 343  GEPGVPGP------PGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPG--- 393
            G  G+PGP      PG  GPPG+P +PG PG   P+   G  GP  +   G QGPPG   
Sbjct: 647  GSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK--GAQGPPGSAG 704

Query: 394  PPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQG 452
            PPG  G  G  G  G+ G  G+ G+ G  GFPG  GDVG KGD+G PG  G RG  GP+G
Sbjct: 705  PPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764

Query: 453  PPG---------PPGPSFRHDKLTFIDMEGS----------GFGGDL------------- 480
            P G         PPG +    KL    + G           GF G L             
Sbjct: 765  PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTG 824

Query: 481  -EALRGPRGFPGPPGPPGVPGLPGEPGRFG-VNSSDVPGPAGLPGVPGREGPPGFPGLPG 538
               L G RG PG  G  G PG  G+PG  G V     PG  G  G+PG +GPPGFPG  G
Sbjct: 825  QPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKG 884

Query: 539  PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPG 598
            PPG  G++G PG  GQ+G L      G +G  G PGPAG  G  G  G  GP G  GPPG
Sbjct: 885  PPGHQGKDGRPGHPGQRGEL------GFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPG 938

Query: 599  PPGPPG-PGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPGLKGDPGVPGLPGAKGE- 655
            PPGPPG  GLP G +  EG+ G          +GP G  G PG KG PG PG  G KG+ 
Sbjct: 939  PPGPPGEQGLP-GLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDK 997

Query: 656  -----VGADGVPGFP---------GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGV-GQP 700
                 VGA+G PG           GLPG+ G  GP GP G +GSRGE+G PG  G  G P
Sbjct: 998  GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIP 1057

Query: 701  GLPGPPGPPGPVVYVSEQ-DGSVLSVP------------GPEGRPGFAGFPGPAGPKGNL 747
            G  GP GPPG      E+ D   +  P            GP G+PG  G  G  GP G  
Sbjct: 1058 GPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGAD 1117

Query: 748  GSKGERGSPGPKGEKGEPG-----SIFSPDG--GALG-PAQKGAKGEPGFRGP---PGPY 796
            G++G RG PG  G+KG+ G      +  P G  G  G P +KG  G+ G  GP   PGP 
Sbjct: 1118 GAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPR 1177

Query: 797  GRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVY 856
            G  G  G  G PG PG  G  G  GEKGE GDA       G PGPPG PG PGP G    
Sbjct: 1178 GPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDA-------GDPGPPGAPGIPGPKG---- 1226

Query: 857  DSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRG 916
            D     +S   G  G PG +GPPG  GAKG VGP G PG          + + G  G++G
Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKG 1286

Query: 917  DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-I 975
            D G  G  G PG  G  G+  PGPPG  GP G+ G  G +GE  +G  G PGP GPPG  
Sbjct: 1287 DPGDVGGPGPPGASGEPGA--PGPPGKRGPSGHMGREGREGE--KGAKGEPGPDGPPGRT 1342

Query: 976  GYEGRQGPPGPPGPPGPPSFPGPHRQ--TISVPGPPGPPGPPGPPGTMG 1022
            G  G +GPPG  GP G    PGP  +   +  PG  GPPGP GP G  G
Sbjct: 1343 GPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPG 1391



 Score =  510 bits (1313), Expect = e-144
 Identities = 349/869 (40%), Positives = 417/869 (47%), Gaps = 134/869 (15%)

Query: 244  SDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEE-- 301
            SDG  G  G       +  +   G+A  P  P P  V     +G    +  + E+ E+  
Sbjct: 678  SDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGT--SGNRGLQGEKGEKGEDGF 735

Query: 302  ---QTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPG 358
               +  V   G Q  PG+      DG    P G   + G  G++G PG  G  G+ G PG
Sbjct: 736  PGFKGDVGLKGDQGKPGAPGPRGEDG----PEGPKGQAGQAGEEGPPGSAGEKGKLGVPG 791

Query: 359  SPCLPGPPG------LPCPVSPLGPAGPALQT----VPGPQGPPGPPGRDGTPG------ 402
             P  PG PG       P P+ P+G  G + +T    + G +GPPG  G  G PG      
Sbjct: 792  LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851

Query: 403  ------RDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPG 455
                  +DG PG PGE G PG  GP GFPG  G  G +G  G PG  G+RG  G QG  G
Sbjct: 852  PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
            PPGP+          +   G  G++  L G RG PGPPGPPG  GLPG  GR G      
Sbjct: 912  PPGPAGV--------LGPQGKTGEVGPL-GERGPPGPPGPPGEQGLPGLEGREGAKGELG 962

Query: 516  P-------GPAGLPGVPGREGPPGFPGLPG------PPGPPGREGPPGRTGQKGSLGEAG 562
            P       GPAGL G PG +G PG PG  G      PPGP G  G PG  G  G  G  G
Sbjct: 963  PPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIG 1022

Query: 563  APGHKGSKGAPGPAGARGESGLAGAPGPAGP---PGPPGPPGPPGPGLPAGFDDMEGS-G 618
             PG  GS+G  GPAG +G  G  G PGP G    PGP GP GPPG   P+G +  +G  G
Sbjct: 1023 LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG 1082

Query: 619  GPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAG--- 675
             P    ++   G  GPPG PG++G  G PG PGA G  G  G PG  G  G +G+ G   
Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVG 1142

Query: 676  ---PQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731
               P G +G  G  GEKG+ G  G +G  G PGP GP GP    +  +G+   +PG  G+
Sbjct: 1143 VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP----TGSEGTP-GLPGGVGQ 1197

Query: 732  PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRG 791
            PG  G  G  G  G+ G  G  G PGPKG+ GE G    P G A  P +KG  GE G +G
Sbjct: 1198 PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDS-GPSGAAGPPGKKGPPGEDGAKG 1256

Query: 792  PPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPP 851
              GP G PG   ++G PG PG  G++G  GEKG+PGD        G PGPPG  G PG P
Sbjct: 1257 SVGPTGLPG---DLGPPGDPGVSGIDGSPGEKGDPGDV-------GGPGPPGASGEPGAP 1306

Query: 852  GTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGE 911
            G P           + GP G  G +G  G KGAKGE GP GPPG+             G 
Sbjct: 1307 GPP----------GKRGPSGHMGREGREGEKGAKGEPGPDGPPGR---------TGPMGA 1347

Query: 912  KGDRGDAGQKGERGEPGGGGFFG----SSLPGPPGPPGPRGYPGIPG---PKGES----I 960
            +G  G  G +G RG PG  G  G        GPPGP GP G PG+ G   PKGE     +
Sbjct: 1348 RGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGL 1407

Query: 961  RGQPGPPGP------QGPPGI-GYEGRQGPPGPPGP------PGPPSFPGPHRQ------ 1001
             G  GPPG       QG PG+ G  G +G PGPPGP      PGPP   GP  Q      
Sbjct: 1408 IGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS 1467

Query: 1002 --TISVPGPPGPPGPPGPPGTMGASSGVR 1028
              ++   G  GP GPPGPPG      G+R
Sbjct: 1468 PGSMGPRGDTGPAGPPGPPGAPAELHGLR 1496



 Score =  509 bits (1311), Expect = e-144
 Identities = 420/1231 (34%), Positives = 510/1231 (41%), Gaps = 261/1231 (21%)

Query: 12   RRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQ-LLGDPPPQQVTQTDDPDVGLAYVF 70
            R  L  +LA L LL G +A   +P  + + +G+     G P          P+   A+  
Sbjct: 11   RAGLCLLLAALQLLPGTQA---DPVDVLKALGVQGGQAGVPEGPGFCPQRTPEGDRAFRI 67

Query: 71   GPDANSGQVARYHFPSLFF-RDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQ 129
            G  +  G      FP   F  +FSLL  +R       VL +I D   A  L G+ L    
Sbjct: 68   GQASTLGIPTWELFPEGHFPENFSLLITLRGQPANQSVLLSIYDERGARQL-GLALGPA- 125

Query: 130  DGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLA 189
                 + LL      G        ++    G+W  +A+S+ G  V L  DCE  Q   L 
Sbjct: 126  -----LGLL------GDPFRPLPQQVNLTDGRWHRVAVSIDGEMVTLVADCEA-QPPVLG 173

Query: 190  RSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQ---------------VSPM 234
               R + +   AGL V          F+G I EL +  DPQ               ++P 
Sbjct: 174  HGPRFISI---AGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDNLAPA 230

Query: 235  HCLDEEGDDSDGASGDSGSGLG-------------------------------DARELLR 263
              +  +G+         G G G                                + ++ +
Sbjct: 231  ATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPK 290

Query: 264  EETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWD 323
             ET A   P  P P  VT+    G ++T   RS + +  T + +L  +     +     D
Sbjct: 291  TETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEE---GD 347

Query: 324  GSVRTPGGRVKE------------GGLKGQKGE-------------PGVPGPPGRAGPPG 358
             S   P  R  E             G KG KGE             PG PGP G  GP G
Sbjct: 348  DSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSG 407

Query: 359  SPCLPGPPGLPCPVSPLGPAG----PALQTVPGP-------------------------- 388
                PGPPG P    P GPAG    P +  + GP                          
Sbjct: 408  P---PGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQA 464

Query: 389  -------------QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ------------- 422
                         +GPPGP G  G PG  G PG PG  G+ G  GPQ             
Sbjct: 465  QAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG 524

Query: 423  -----------GFPGTPGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHD 464
                       G  G PGD GPKGD+G  G+       G+RG  G  G PGPPG      
Sbjct: 525  RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584

Query: 465  KLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGV---------------PGLPGEPGRFG 509
                    G         L GPRG PGP G PGV               PG PG PG+ G
Sbjct: 585  AEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644

Query: 510  VNSSD-VPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568
             + S  +PGP GL G PG +GPPG PG+PG PG  G  G PG  G  G  G  G PG  G
Sbjct: 645  NHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAG 704

Query: 569  SKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSA 628
              G PGP G +G SG  G  G  G  G  G PG  G     G     G+ GP     R  
Sbjct: 705  PPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGP-----RGE 759

Query: 629  DGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGRE---GIAGPQGPKGDRGS 685
            DGP+GP G  G  G+ G PG  G KG++G  G+PG+PG PG +   G  GP GP G++G 
Sbjct: 760  DGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK 819

Query: 686  RGEKGDPGKDGV----------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF- 734
             G+ G PG +G           GQPG  G PGP G V     QDG+   +PG +G PG  
Sbjct: 820  SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDV----GQDGAP-GIPGEKGLPGLQ 874

Query: 735  --AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSP-DGGALGPAQK-GAKGEPGFR 790
               GFPGP GP G+ G  G  G PG +GE G  G    P   G LGP  K G  G  G R
Sbjct: 875  GPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGER 934

Query: 791  GPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGP 850
            GPPGP G PG +G  G  GR G  G  G  G  G+ G A    G+RG PGP G PG PGP
Sbjct: 935  GPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPA----GLRGFPGPKGGPGDPGP 990

Query: 851  PGT--------PVYDSNVFAESSRPGP------PGLPGNQGPPGP---KGAKGEVGPPGP 893
             G         PV  +    E    GP      PG  G++GP GP   KG++GE GPPGP
Sbjct: 991  TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050

Query: 894  PGQ--FPFDFLQL----EAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR 947
             G+   P     L     A   GE+GD+GD G  G +G  G  G  G   PG PG  GP 
Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGP--PGQPGIRGPA 1108

Query: 948  GYPGIPGPKG-ESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPP---------SFP 996
            G+PG PG  G +  RG PG  G +G  G+ G+ G  GPPG  G PGPP            
Sbjct: 1109 GHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSM 1168

Query: 997  GPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1027
            GPH      PGP GP GP G  GT G   GV
Sbjct: 1169 GPH----GAPGPRGPQGPTGSEGTPGLPGGV 1195



 Score =  487 bits (1254), Expect = e-137
 Identities = 331/805 (41%), Positives = 378/805 (46%), Gaps = 114/805 (14%)

Query: 309  GAQTLPGSDSVST---WDGSVRTPGGRVKEG-----------GLKGQKGEPGVPGPPGRA 354
            GA+ LPG         +DG    PG + + G           G  G++G  G PGP G+A
Sbjct: 536  GARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQA 595

Query: 355  GPPGSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGEPGDP 410
            G PG   L GP G P P    G  G    P  +   GP G PGPPG+ G  G  G PG  
Sbjct: 596  GEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655

Query: 411  GEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-------VGERGPPGPQGPPGPPGPSFRH 463
            G  G PG+ GP G PG PG  G  G  G PG        G +GPPG  GPPG PGP    
Sbjct: 656  GLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVK 715

Query: 464  DKLTFIDMEGS----------GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSS 513
                   ++G           GF GD+  L+G +G PG PGP G  G  G  G+ G    
Sbjct: 716  GTSGNRGLQGEKGEKGEDGFPGFKGDV-GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774

Query: 514  DVP----------GPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGA 563
            + P          G  GLPG PGR GP G  G PGP GP G +G  G+TGQ G  GE G 
Sbjct: 775  EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP 834

Query: 564  PGHKGSKGAPG------PAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGS 617
            PG +G +G PG      P G  G+ G  G PG  G PG  GPPG PGP  P G    +G 
Sbjct: 835  PGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGR 894

Query: 618  GG-PFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG------FPGLPGR 670
             G P         G  GPPG  G+ G  G  G  G  GE G  G PG       PGL GR
Sbjct: 895  PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGR 954

Query: 671  EGIAG---PQGPKGDRGSRGEKGDPG-KDGVGQPG---LPGPPGPPGPV-VYVSEQDGSV 722
            EG  G   P GP G  G  G +G PG K G G PG   L G  GPPGPV    S  +   
Sbjct: 955  EGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014

Query: 723  LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALGPAQ 780
            L   G  G PG +G  GP GP G  GS+GERG PGP G+ G PG +  P G  GA GP+ 
Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPL-GPLGPPGAAGPSG 1073

Query: 781  K----------GAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG---EPG 827
            +          G KG  G +G  GP G+PG +G  G PG PG  G  G +G  G   + G
Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133

Query: 828  DASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE 887
            D  +  G  G+ GPPG  G PGPPG    +     +    GP G PG +GP GP G++G 
Sbjct: 1134 DDGVR-GFVGVIGPPGLQGLPGPPG----EKGEVGDVGSMGPHGAPGPRGPQGPTGSEGT 1188

Query: 888  VGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFG-------SSLPGP 940
             G PG  GQ             GEKG+RGDAG  G  G PG  G  G       S   G 
Sbjct: 1189 PGLPGGVGQ---------PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGA 1239

Query: 941  PGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPH 999
             GPPG +G PG  G KG    G  G PG  GPPG  G  G  G PG  G PG    PGP 
Sbjct: 1240 AGPPGKKGPPGEDGAKGSV--GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP- 1296

Query: 1000 RQTISVPGPPGPPGPPGPPGTMGAS 1024
                  PG  G PG PGPPG  G S
Sbjct: 1297 ------PGASGEPGAPGPPGKRGPS 1315



 Score =  342 bits (877), Expect = 1e-93
 Identities = 243/623 (39%), Positives = 275/623 (44%), Gaps = 107/623 (17%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEG-----GLKGQKGEPGVPGPPGRAGPPGSPCLP 363
            G Q LPG +      G +  PG   KEG     G  G KG PG PGP G  G  G P   
Sbjct: 944  GEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPV 1003

Query: 364  GPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 422
            G  G P    PLGPAG   L    G +GP GP G+ G+ G  G PG  G+DG PG  GP 
Sbjct: 1004 GANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPL 1063

Query: 423  GFPGTPGDVGPKGDKGDPGV----------GERGPPG------PQGPPGPPGPSFRHDKL 466
            G PG  G  G +GDKGD G           G+ GPPG      P G PGPPG      + 
Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRR 1123

Query: 467  TFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------VNSSDVPGPA 519
                + G   G D     G RGF G  GPPG+ GLPG PG  G       +     PGP 
Sbjct: 1124 GPPGLFGQK-GDD-----GVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPR 1177

Query: 520  G---------LPGVPGR------------------EGPPGFPGLPGPPG----------- 541
            G          PG+PG                    GPPG PG+PGP G           
Sbjct: 1178 GPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPS 1237

Query: 542  ----PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597
                PPG++GPPG  G KGS+G  G PG  G  G PG +G  G  G  G PG  G PGPP
Sbjct: 1238 GAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPP 1297

Query: 598  GP------PGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPG 651
            G       PGPPG   P+G    EG  G     A+   GP GPPG  G  G  G PG  G
Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGREGE--KGAKGEPGPDGPPGRTGPMGARGPPGRVG 1355

Query: 652  AKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPG 710
             +G  G  G  G PGL G  G  GP GP G  G  G KGD G  G  G  GL G  GPPG
Sbjct: 1356 PEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPG 1415

Query: 711  PVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS 770
                  +Q      +PG +G PG  G PGP GP G+LG  G  G  GP G+KG  GS   
Sbjct: 1416 EAGEKGDQ-----GLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGS--- 1467

Query: 771  PDGGALGPAQKGAKGEPGFRGPPGPYGRP----GYKGEIGFPGRPGRPGMNGLKGEKGEP 826
                   P   G +G+ G  GPPGP G P    G +    F   P      GL  E+   
Sbjct: 1468 -------PGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGGL--EEVLA 1518

Query: 827  GDASLGFGMRGMPGPPGPPGPPG 849
               SL   +  +  PPG    PG
Sbjct: 1519 SLTSLSLELEQLRRPPGTAERPG 1541



 Score =  266 bits (679), Expect = 1e-70
 Identities = 178/455 (39%), Positives = 199/455 (43%), Gaps = 64/455 (14%)

Query: 239  EEGDDSD-------GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSST 291
            EEGD  D       G+ GD G      +  +R   G    P          PP   G   
Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133

Query: 292  EDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRT------PGGRVKEG--------G 337
            +D     V     +   G Q LPG        G V +      PG R  +G        G
Sbjct: 1134 DDGVRGFVG---VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPG 1190

Query: 338  LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR 397
            L G  G+PG  G  G  G  G P  PG PG+P P   +G  G +     GP G  GPPG+
Sbjct: 1191 LPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDS-----GPSGAAGPPGK 1245

Query: 398  DGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG-VGERGPPGPQGPPGP 456
             G PG DG  G  G  G PGD GP G PG  G  G  G+KGDPG VG  GPPG  G PG 
Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305

Query: 457  PGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPG---LPGEPGRFGVNSS 513
            PGP  +      +  EG       E  +G +G PGP GPPG  G     G PGR G    
Sbjct: 1306 PGPPGKRGPSGHMGREGR------EGEKGAKGEPGPDGPPGRTGPMGARGPPGRVG---- 1355

Query: 514  DVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAP 573
                P GL G+PG  G PG  G PG  GPPG  GP G  G KG  G  G  GH G  G  
Sbjct: 1356 ----PEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLI 1411

Query: 574  GPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQG 633
            GP G  GE G  G PG  GPPGP G PGPPGP        +   G P         GP G
Sbjct: 1412 GPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGP--------IGSLGHP---------GPPG 1454

Query: 634  PPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLP 668
              G  G KG  G PG  G +G+ G  G PG PG P
Sbjct: 1455 VAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489



 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 92/292 (31%), Positives = 112/292 (38%), Gaps = 47/292 (16%)

Query: 769  FSPDGGALGPAQKGA-KGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEK---- 823
            + PD   L PA   A +GEP     P P  +   KG     GR G+    G K  K    
Sbjct: 220  YLPDCDNLAPAATVAPQGEPE---TPRPRRKGKGKGRKKGRGRKGK----GRKKNKEIWT 272

Query: 824  -GEPGDASLGFGMRGMPGP--PGPPGPPGPPGTPVYDSNVFAES------SRPGPPGLPG 874
               P D++       +P    P P  PP P  TP+  ++            R   P    
Sbjct: 273  SSPPPDSAENQTSTDIPKTETPAPNLPPTP--TPLVVTSTVTTGLNATILERSLDPDSGT 330

Query: 875  NQGPPGPKGAK----GEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG 930
              G    K A+    G+    GP      DF   E   + +      AG+KG +GEP   
Sbjct: 331  ELGTLETKAAREDEEGDDSTMGP------DFRAAEYPSRTQFQIFPGAGEKGAKGEPAVI 384

Query: 931  GFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGI-GYEGRQGPPGPP- 987
               G    GPPG PGP+G  G  GP G     G PGPPGP G PGI G +G +GPPG   
Sbjct: 385  EK-GQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVI 443

Query: 988  ---------GPPGPP-SFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRL 1029
                        GPP SF     Q +         GPPGP G  G    V L
Sbjct: 444  MMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGL 495


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  512 bits (1318), Expect = e-144
 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G  GD G         LR + G      +P  P V   P   G   E + S E  +Q   
Sbjct: 551  GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 360
               G+   PG        G    PG G   E GL+G +G PG PGPPG AGP G    S 
Sbjct: 599  GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 413
             +PGPPG P      GP G      PGPQGPPG PG        G PG DGEPG PG   
Sbjct: 653  PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 414  -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 457
             G PG  G QGFPGT               PG  G  G KG+P V   G PG  G PG  
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 458  GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 517
            G S  H ++    + G       E L GPRG PG PGPPG  G PG        +  +PG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 518  PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572
              GL G  GR G   P G PG+PG    G PG  G PG  G +G +G  G  G+ G+ G 
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 573  PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 628
             GP G  G  G+ G PG  GPPGPPG PG PG    PG+P G     G+ G     A+  
Sbjct: 882  LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935

Query: 629  DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682
             G +G PG      + G KG+PG+ G  G  GE G  GVPG PGL G +G+ GP GP G 
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 683  RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 737
            RG  G  G+PG+ G+ G PG  G  G PG     S+     L  PG  GRPG  G     
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 738  -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 772
                         PGP GP G+      +G KGE G PGP G       +G PGS  SP 
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 773  -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824
              G  GP         KG  G PG RGPPG  G PG  G +G  G  GR G+ G  GEKG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 825  EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 873
            E G      G RG PG  G  G  G PG P       A               PGPPGLP
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 874  G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925
            G        N+GPPG +G+ G  GPPGPPG          + + G KGD+G  G  G +G
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280

Query: 926  EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 984
             PG  G  G     PPG  G  G PG+PGP+G+   +G PG  G +G PG  + G  GPP
Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333

Query: 985  GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1022
            GP GP GPP   G     + IS+PG PGPPG PG PG  G
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373



 Score =  480 bits (1235), Expect = e-135
 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%)

Query: 243  DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302
            D+    GD G+         R   G +  P +P  P  + P L G       +  + E  
Sbjct: 348  DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407

Query: 303  TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 362
                   A   PGS   +   G   +PG     G +  +KG PG  G PG  G PG P +
Sbjct: 408  RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465

Query: 363  PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419
             GP   PGL C   P  P  P L  +PG  G  G PGR G  G  G PG PG  G PG  
Sbjct: 466  DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524

Query: 420  GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 465
               GFPG  GD G KG+K             GDPG+ G+ G  G  G PG PG       
Sbjct: 525  --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575

Query: 466  LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 521
                 ++G  G  G+L AL G +G  GPPG PG PG PG  G     G      PG  G 
Sbjct: 576  -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629

Query: 522  PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568
             GVPG  GPPG              PG PGPPGPPG  GP G  G  GSLG+ G PG  G
Sbjct: 630  QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 569  SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 615
              G         PGP G +G+ G  G  G  G PG  G PG PG PGLP    +      
Sbjct: 690  PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 616  -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 670
             G G P +   R   G  G    PGLPGL G PG  GL G +G+ G  G PG  G PGR 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 671  ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 718
                       G+ G +G +G RG  G KGDPG  G+ + G PG  G PG   +  E   
Sbjct: 810  IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869

Query: 719  --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 755
                    +  +L  PG +G  G  GFP   GP GP GN G+            KG+RG+
Sbjct: 870  LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 756  PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 795
            PG KGE+G+ G+    +              G A  P +KG +G P      G +G PGP
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 796  YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 847
             G PG +G++G  G PG PG+ G+ G  G  G         +LGF G  G PG PG  G 
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 848  PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 901
             G  G P Y     +E +RPGPPG  G+ G PG  G KGE+G PGPPG            
Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 902  LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 939
                  + G+ G  GD G K         G RG PG  GF GS              +PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 940  PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 988
            P G          PPGPRG PG  G KG+  RG PG PG  G  G +G  G +GP G  G
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222

Query: 989  PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1020
             PGPP  PG        +R      G PG PGPPGPPG+
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261



 Score =  470 bits (1209), Expect = e-132
 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 365
            G + LPG      + G     G +   G  GL G  G PG+PG PG  GP G   +PG  
Sbjct: 67   GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126

Query: 366  --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 405
                    PGLP     LG P  P    + G +G P           G PG  G PG  G
Sbjct: 127  GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183

Query: 406  EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 462
             PG PG  G  G  GP GF G PG +GP+G KG  G   +G +G  G +G  GPPGP   
Sbjct: 184  LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240

Query: 463  HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 505
                  + + G     DL+  +G +G    PGPPGP              PG PGL G+P
Sbjct: 241  -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299

Query: 506  GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 537
            G+ GV     S  V G  G PG+ G +         GPPGF                G P
Sbjct: 300  GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359

Query: 538  GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574
            GPPGP                       PG  G PG  G KGS GE G PG K + G PG
Sbjct: 360  GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418

Query: 575  PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 623
              G  G  GL G+PGP GPP       GPPG  G PG    PG+P G D  +G  G   +
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477

Query: 624  TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677
                  GP G PGLPGL G  G+P      GL G+ G  G  G+PGFPG PG +G  G +
Sbjct: 478  QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 678  GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 723
            G K             GD G RG+ G  G DG+ G PG+ G PGP G +    E+     
Sbjct: 538  GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595

Query: 724  SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 770
               GP G PG  G PGPAGP G             G++G  G+PGP GE G  G  S+ +
Sbjct: 596  ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 771  PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 822
            P  G  GP   G  G PG +GPPG  G  G  G+ G PG  G PG+ G+        KG+
Sbjct: 653  PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710

Query: 823  KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 864
            +G PG   SLG     G  G+PG PG PG         PG PGTP +     +S    E 
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 865  SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 916
              PG PGLPG  G  G  G +G+ G PGPPG+       +E          + G KG +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 917  DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 974
              G+ G +G+PG  G   S  PG  G PG  G+ G  GP G+  RG PG PG  GPPG  
Sbjct: 831  RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888

Query: 975  --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
              IG  G  G  GPPGPPG P  PG  R +  +PG  G  G PG  G  G
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937



 Score =  464 bits (1193), Expect = e-130
 Identities = 352/942 (37%), Positives = 404/942 (42%), Gaps = 223/942 (23%)

Query: 267  GAALKPRLPAPPPVTTP-PLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGS 325
            G +  P LP  P  T P  L G      S+ E+        +LG   +PG+       G 
Sbjct: 100  GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLP-GTLGYPGIPGAA------GL 152

Query: 326  VRTPGGRVKEGGLK-GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP------------- 371
                G   KE  ++   KG+PG+PG PG  G PG P  PGP G P P             
Sbjct: 153  KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212

Query: 372  ----------------------VSPLGPAGPALQTVPGPQ---------------GPPGP 394
                                    P GP G  + T+ GP                G PGP
Sbjct: 213  GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272

Query: 395  PGRDGTPGRD-----GEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GER 445
            PG  G PG       G PGDPG  GKPG  G  GFPG+ G    KG++G PG+    G +
Sbjct: 273  PGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG---VKGNRGFPGLMGEDGIK 329

Query: 446  GPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEP 505
            G  G  GPPG  GP+  +D  T+ +    G  G      GPRG  GP GP G PG+PG P
Sbjct: 330  GQKGDIGPPGFRGPTEYYD--TYQEKGDEGTPGP----PGPRGARGPQGPSGPPGVPGSP 383

Query: 506  GRFGVNSSDVPGPAGL-----------------PGVPGREGPPGFPGLPGPPGPPG---- 544
            G         PG  GL                 PG PG  G PG PG PGPPGPPG    
Sbjct: 384  GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443

Query: 545  REGPPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----------------GARGESGLAGA 587
            R+GPPG  G  G LG  G PG  G KG PG                   G  G  G+ G 
Sbjct: 444  RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGR 503

Query: 588  PGPAGPPGPPGPPGPPG-PGLPAGFDDMEGSGGPFWSTARSA--DGPQGPPGLPGLKGDP 644
             G AG  G PG PG  G PG P GF   +G  G       +   +G  G PG PGL+G P
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFP-GFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 645  G------------VPGLPGAKGEV------GADGVPGFPGLPGREGIAGPQGPKGDRGSR 686
            G            V GLPG KGE+      G  G PG PG PG  G AGP GP G     
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG----Y 618

Query: 687  GEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKG 745
            G +G+PG  G  G PG PGPPG  GP   +S        VPGP G PG  G PGP GP G
Sbjct: 619  GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST----PVPGPPGPPGPPGHPGPQGPPG 674

Query: 746  ---NLGSKGERGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRGPPGPYGR 798
               +LG  G+ G PGP GE G PG  F    G  G    P  KG+ G PG  G PG  G+
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734

Query: 799  PGY---KGE--IGFPGRPGRPGMNGLKGEKGEPGDASLGF--------------GMRGMP 839
            PG    KGE  +  PG PG PG  G +G  GE G+  L                G RG P
Sbjct: 735  PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 840  GPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899
            G PGPPG  GPPG  +       E  R G  GLPG  G  G +G +G+ GP G PG    
Sbjct: 795  GQPGPPGEQGPPGRCI-------EGPR-GAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGL 846

Query: 900  DFLQLEAEM--KGEKGDRGDAGQKGERGEPGGGGFFGS-------------------SLP 938
            D      E    G  G +G+ G  G+RG PG  G  G                      P
Sbjct: 847  DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906

Query: 939  GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI----------------GYEGRQG 982
            G PG PG RG PGIPG KG+  RG PG  G QG  G                 G +G  G
Sbjct: 907  GNPGTPGQRGSPGIPGVKGQ--RGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAG 964

Query: 983  PPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1024
             PG  G  G P  PG       + G PGP GPPGP G +G++
Sbjct: 965  NPGEKGNRGVPGMPGLK----GLKGLPGPAGPPGPRGDLGST 1002



 Score =  458 bits (1178), Expect = e-128
 Identities = 322/776 (41%), Positives = 365/776 (47%), Gaps = 129/776 (16%)

Query: 337  GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 396
            G KG+KGE G PGPPG  G  G     GP GLP P  P G  G     +PG  G  G  G
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKG---FTGPEGLPGPQGPKGFPG-----LPGLTGSKGVRG 94

Query: 397  RDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPG 455
              G PG  G PG PG    PG+TGP G  G PG  G KG++G PG+ G  G PG  G  G
Sbjct: 95   ISGLPGFSGSPGLPGT---PGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151

Query: 456  PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDV 515
              G      K   I+++  G  G L    GP+G PGPPG PG  G PG PG FG   +  
Sbjct: 152  LKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMG 210

Query: 516  P-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGAP 564
            P GP G  G  V G +G  G  GL GPPGPPG       GP  RT   G+KG  G  G P
Sbjct: 211  PRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEP 270

Query: 565  GHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGG 619
            G  G  G PG +     GA G+ GL G PG  G PG PG  G  G     GF  + G  G
Sbjct: 271  GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN---RGFPGLMGEDG 327

Query: 620  PFWSTARSADGPQGPPGLPGL---------KGDPGVPGLPG---AKGEVGADGVPGFPGL 667
                  +   G  GPPG  G          KGD G PG PG   A+G  G  G PG PG 
Sbjct: 328  -----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGS 382

Query: 668  PG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV 725
            PG  R G+ G  G  G +GS+GE+G PGKD +G PG PG  G PG           +   
Sbjct: 383  PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG-----------LPGS 431

Query: 726  PGPEGRPGFAGF-PGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS-------PDGGALG 777
            PGP G PG   F  GP G  G  G  G  G PG  G KGEPG + +       P G    
Sbjct: 432  PGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGL 491

Query: 778  PAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG---LKGEKGE--------- 825
            P   G KG PG +G  G  G PG  G  G PG PG PG  G   LKGEKGE         
Sbjct: 492  PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG 551

Query: 826  -PGDASLGF-----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPP 879
             PGD  L       G+ G+PG PG  G PGP G    +  +  E    GPPG PG+ G P
Sbjct: 552  VPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG----ELALSGEKGDQGPPGDPGSPGSP 607

Query: 880  GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPG 939
            GP       GP GPPG  P    Q E  ++G +G  G  G  GE G P G     + +PG
Sbjct: 608  GP------AGPAGPPGYGP----QGEPGLQGTQGVPGAPGPPGEAG-PRGELSVSTPVPG 656

Query: 940  PPGPPGPRGYPGIPGPKGESIR----GQPGPPGPQGPPGIGYEGRQGPPGP--------- 986
            PPGPPGP G+PG  GP G        G PG PGP G PGI   G  GPPGP         
Sbjct: 657  PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGT 716

Query: 987  ------------PGPPGPPSFPGPHRQ-TISVPGPPGPPGPPGPPGTMGASSGVRL 1029
                        PG PG P  PG   +  +++PG PG PG PG  G  G    + L
Sbjct: 717  KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772



 Score =  404 bits (1038), Expect = e-112
 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%)

Query: 436  DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491
            DKG    D   GE+G  G  GPPG PG                GF        GP G PG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73

Query: 492  PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 547
            P GP G PGLPG  G  GV   S +PG     GLPG PG  GP G  G+PG  G  G +G
Sbjct: 74   PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133

Query: 548  PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 602
             PG  G  G  G  GA G KG KGAP         A+G+ GL GAPGP G PGPPG PGP
Sbjct: 134  FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193

Query: 603  PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 636
             GP  P GF    G+ GP        +               GP GPPG           
Sbjct: 194  VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253

Query: 637  ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 682
               L G KGD G  G PG  G           E GA G PG  G PG++G+ G  G +G 
Sbjct: 254  RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313

Query: 683  RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 740
            +G+RG  G  G+DG+ GQ G  GPPG  GP  Y    Q+      PGP G  G  G  GP
Sbjct: 314  KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373

Query: 741  AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 791
            +GP G  GS G      RG+PG  G KG  G    P   A+G    P   G+ G PG  G
Sbjct: 374  SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433

Query: 792  PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 832
            PPGP G    R G  G+ G PG  G PG+ G+ G KGEPG                    
Sbjct: 434  PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 833  -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 887
              G++G+PG  G  G  G PG+P         +  PG PG PG QG PG KG KGE    
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546

Query: 888  ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 935
               VG PG PG      +   D +     +KG  G +G+   +G+KG++G PG  G  GS
Sbjct: 547  EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606

Query: 936  SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 973
              PGP GP GP GY              PG PGP GE+  RG+       PGPPGP GPP
Sbjct: 607  --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 974  GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1023
            G  + G QGPPG P   G  G P  PGP  +     I  PGPPGP G  G PGT G+
Sbjct: 665  G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719



 Score =  398 bits (1022), Expect = e-110
 Identities = 276/703 (39%), Positives = 313/703 (44%), Gaps = 142/703 (20%)

Query: 272  PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331
            P  P PP    PP   G   E  R             GAQ LPG + +    G     G 
Sbjct: 794  PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837

Query: 332  RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 384
            +   G       G  G+ G PG+PG  G  GP G    PG PG+  P    G  G  +  
Sbjct: 838  KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895

Query: 385  VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 438
             PG  GPPGPPG  GTPG+ G PG PG  G+ G  G +G  G  G+ GP       GDKG
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 439  DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 492
            +PG+ G  G PG +G  G PG                G  G L+ L GP G PGP     
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000

Query: 493  ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 536
                PG PG+ G+PG  G  G+  S   G  G  G PGR G PG PG+            
Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058

Query: 537  -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPA 591
                 PGPPGP G  G PG  G+KG +G+ G PGH G  G  G  G+ G  GL G PGP 
Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118

Query: 592  GPPG---------PPGPPGPPG-PGLPAGFDDMEGSGGPFWSTA-RSADGPQGPPGLPG- 639
            G  G         PPG  GPPG PG P       GS GP      +  DG  GP G  G 
Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFP-------GSPGPMGIRGDQGRDGIPGPAGEKGE 1171

Query: 640  ---LKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG 696
               L+  PG  G PGA+G  G  G PGFPGLPGR+G  G  GP+G  G  G  G PG  G
Sbjct: 1172 TGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG 1231

Query: 697  V---------------GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741
                            G PG PGPPGPPG  V   + D   +  PGP+G PG AG     
Sbjct: 1232 AIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG---DM 1288

Query: 742  GPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGY 801
            GP G LG+ G  G PGP+G+ G  G           P  KG KG PGF G  GP G  G 
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGF----------PGVKGEKGNPGFLGSIGPPGPIGP 1338

Query: 802  KGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVF 861
            KG  G  G PG   +  L G  G PG      GM+G PGPPGPPG  GP G         
Sbjct: 1339 KGPPGVRGDPGTLKIISLPGSPGPPGTPGEP-GMQGEPGPPGPPGNLGPCG--------- 1388

Query: 862  AESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQL 904
                   P G PG  G PG  G  GE G  G  G+    F QL
Sbjct: 1389 -------PRGKPGKDGKPGTPGPAGEKGNKGSKGEPESLFHQL 1424



 Score =  327 bits (839), Expect = 4e-89
 Identities = 229/609 (37%), Positives = 272/609 (44%), Gaps = 112/609 (18%)

Query: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300
            G D  G  G++GS      +    E G   +   P  P +  PP   G          + 
Sbjct: 845  GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901

Query: 301  EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 347
                  + G     GS  +    G   TPG + ++G            + G KGEPG+  
Sbjct: 902  PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961

Query: 348  ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 393
                PG  G  G PG P L G  GLP P  P GP G          P L+ +PG  G  G
Sbjct: 962  FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 394  PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 433
             PG  G       PGR G PG PG  G              +PG  GP G PG PGD+G 
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081

Query: 434  KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492
            KG+ G PG  G  GP GP+G PG PG      K         G  GDL   +G +G  GP
Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132

Query: 493  PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 541
            PG   PPG+PG PG PG  G+        +PGPAG  G  G      GP G PG  G  G
Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192

Query: 542  PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 596
              G  G PG  G+KG++G+AG  G  G +G PGP G  G     ++G  G PG  G PG 
Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252

Query: 597  PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 650
            PGPPGPPG  +     D    G P         GP+GPPG       PG  G PG PGLP
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303

Query: 651  GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 706
            G +G+ G  G PG  G    PG  G  GP GP G +G  G +GDPG    +  PG PGPP
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363

Query: 707  GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 763
            G PG               PG +G PG  G PG   P GP+G  G  G+ G+PGP GEKG
Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 764  EPGSIFSPD 772
              GS   P+
Sbjct: 1410 NKGSKGEPE 1418



 Score =  276 bits (706), Expect = 1e-73
 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%)

Query: 567  KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626
            KG     G  G +GE G  G PG  G  G  GP G PGP  P GF  + G  G       
Sbjct: 36   KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88

Query: 627  SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 674
             + G +G  GLPG  G PG+PG PG  G  G  GVPG         FPGLP   G  GI 
Sbjct: 89   -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147

Query: 675  GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734
            G  G KG +G+  ++ D   D  G PGLPG                     PGP+G PG 
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187

Query: 735  AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 794
             GFPGP GP G  G  G  G+ GP+G KG  G         +G   KG +G  G  GPPG
Sbjct: 188  PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239

Query: 795  PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 835
            P G                G KG+ G  G PG PG +GL GE     KG PGD     G+
Sbjct: 240  PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295

Query: 836  RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895
            +G PG  G PG PG  G               G  G PG  G  G KG KG++GPPG  G
Sbjct: 296  QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342

Query: 896  QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 953
              P ++     E KG++G  G  G +G RG  G  G  G  +PG PG   PG RG PG P
Sbjct: 343  --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397

Query: 954  GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1005
            G KG +  RG+PG    G  G PG  G  G  G PGPPGPPG   F    PG H      
Sbjct: 398  GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451

Query: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATR 1033
             G PG  G PG PG  G      L  T+
Sbjct: 452  -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478



 Score =  168 bits (426), Expect = 3e-41
 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%)

Query: 766  GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 816
            G +    G       KG KGE GF GPP         GP G PG +G  GFPG PG  G 
Sbjct: 30   GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89

Query: 817  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 853
             G++G  G PG +    G  G+PG PG  GP                  PG PGT     
Sbjct: 90   KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 854  -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899
                         P  + ++  ++   PG PG PG QG PGP G  G VGPPGPPG F F
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 900  DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 951
                     KG  G+R   G KGERG  G        L GPPGPP        GP     
Sbjct: 206  PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256

Query: 952  IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1010
            + G KG+    G+PGPPGP G PG  Y   +G PG PG  G P   G        PG  G
Sbjct: 257  LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312

Query: 1011 PPGPPGPPGTMG 1022
              G  G PG MG
Sbjct: 313  VKGNRGFPGLMG 324


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  512 bits (1318), Expect = e-144
 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G  GD G         LR + G      +P  P V   P   G   E + S E  +Q   
Sbjct: 551  GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 360
               G+   PG        G    PG G   E GL+G +G PG PGPPG AGP G    S 
Sbjct: 599  GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 413
             +PGPPG P      GP G      PGPQGPPG PG        G PG DGEPG PG   
Sbjct: 653  PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 414  -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 457
             G PG  G QGFPGT               PG  G  G KG+P V   G PG  G PG  
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 458  GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 517
            G S  H ++    + G       E L GPRG PG PGPPG  G PG        +  +PG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 518  PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572
              GL G  GR G   P G PG+PG    G PG  G PG  G +G +G  G  G+ G+ G 
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 573  PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 628
             GP G  G  G+ G PG  GPPGPPG PG PG    PG+P G     G+ G     A+  
Sbjct: 882  LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935

Query: 629  DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682
             G +G PG      + G KG+PG+ G  G  GE G  GVPG PGL G +G+ GP GP G 
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 683  RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 737
            RG  G  G+PG+ G+ G PG  G  G PG     S+     L  PG  GRPG  G     
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 738  -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 772
                         PGP GP G+      +G KGE G PGP G       +G PGS  SP 
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 773  -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824
              G  GP         KG  G PG RGPPG  G PG  G +G  G  GR G+ G  GEKG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 825  EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 873
            E G      G RG PG  G  G  G PG P       A               PGPPGLP
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 874  G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925
            G        N+GPPG +G+ G  GPPGPPG          + + G KGD+G  G  G +G
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280

Query: 926  EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 984
             PG  G  G     PPG  G  G PG+PGP+G+   +G PG  G +G PG  + G  GPP
Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333

Query: 985  GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1022
            GP GP GPP   G     + IS+PG PGPPG PG PG  G
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373



 Score =  480 bits (1235), Expect = e-135
 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%)

Query: 243  DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302
            D+    GD G+         R   G +  P +P  P  + P L G       +  + E  
Sbjct: 348  DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407

Query: 303  TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 362
                   A   PGS   +   G   +PG     G +  +KG PG  G PG  G PG P +
Sbjct: 408  RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465

Query: 363  PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419
             GP   PGL C   P  P  P L  +PG  G  G PGR G  G  G PG PG  G PG  
Sbjct: 466  DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524

Query: 420  GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 465
               GFPG  GD G KG+K             GDPG+ G+ G  G  G PG PG       
Sbjct: 525  --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575

Query: 466  LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 521
                 ++G  G  G+L AL G +G  GPPG PG PG PG  G     G      PG  G 
Sbjct: 576  -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629

Query: 522  PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568
             GVPG  GPPG              PG PGPPGPPG  GP G  G  GSLG+ G PG  G
Sbjct: 630  QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 569  SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 615
              G         PGP G +G+ G  G  G  G PG  G PG PG PGLP    +      
Sbjct: 690  PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 616  -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 670
             G G P +   R   G  G    PGLPGL G PG  GL G +G+ G  G PG  G PGR 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 671  ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 718
                       G+ G +G +G RG  G KGDPG  G+ + G PG  G PG   +  E   
Sbjct: 810  IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869

Query: 719  --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 755
                    +  +L  PG +G  G  GFP   GP GP GN G+            KG+RG+
Sbjct: 870  LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 756  PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 795
            PG KGE+G+ G+    +              G A  P +KG +G P      G +G PGP
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 796  YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 847
             G PG +G++G  G PG PG+ G+ G  G  G         +LGF G  G PG PG  G 
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 848  PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 901
             G  G P Y     +E +RPGPPG  G+ G PG  G KGE+G PGPPG            
Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 902  LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 939
                  + G+ G  GD G K         G RG PG  GF GS              +PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 940  PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 988
            P G          PPGPRG PG  G KG+  RG PG PG  G  G +G  G +GP G  G
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222

Query: 989  PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1020
             PGPP  PG        +R      G PG PGPPGPPG+
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261



 Score =  470 bits (1209), Expect = e-132
 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 365
            G + LPG      + G     G +   G  GL G  G PG+PG PG  GP G   +PG  
Sbjct: 67   GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126

Query: 366  --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 405
                    PGLP     LG P  P    + G +G P           G PG  G PG  G
Sbjct: 127  GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183

Query: 406  EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 462
             PG PG  G  G  GP GF G PG +GP+G KG  G   +G +G  G +G  GPPGP   
Sbjct: 184  LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240

Query: 463  HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 505
                  + + G     DL+  +G +G    PGPPGP              PG PGL G+P
Sbjct: 241  -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299

Query: 506  GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 537
            G+ GV     S  V G  G PG+ G +         GPPGF                G P
Sbjct: 300  GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359

Query: 538  GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574
            GPPGP                       PG  G PG  G KGS GE G PG K + G PG
Sbjct: 360  GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418

Query: 575  PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 623
              G  G  GL G+PGP GPP       GPPG  G PG    PG+P G D  +G  G   +
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477

Query: 624  TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677
                  GP G PGLPGL G  G+P      GL G+ G  G  G+PGFPG PG +G  G +
Sbjct: 478  QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 678  GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 723
            G K             GD G RG+ G  G DG+ G PG+ G PGP G +    E+     
Sbjct: 538  GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595

Query: 724  SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 770
               GP G PG  G PGPAGP G             G++G  G+PGP GE G  G  S+ +
Sbjct: 596  ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 771  PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 822
            P  G  GP   G  G PG +GPPG  G  G  G+ G PG  G PG+ G+        KG+
Sbjct: 653  PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710

Query: 823  KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 864
            +G PG   SLG     G  G+PG PG PG         PG PGTP +     +S    E 
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 865  SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 916
              PG PGLPG  G  G  G +G+ G PGPPG+       +E          + G KG +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 917  DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 974
              G+ G +G+PG  G   S  PG  G PG  G+ G  GP G+  RG PG PG  GPPG  
Sbjct: 831  RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888

Query: 975  --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
              IG  G  G  GPPGPPG P  PG  R +  +PG  G  G PG  G  G
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937



 Score =  454 bits (1168), Expect = e-127
 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%)

Query: 337  GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 395
            G KG+KGE G PGPPG          PG  G   P    GP GP     +PG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93

Query: 396  GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 454
            G  G PG  G PG P   G PG+TGP G  G PG  G KG++G PG+ G  G PG  G  
Sbjct: 94   GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150

Query: 455  GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 514
            G  G      K   I+++  G  G L    GP+G PGPPG PG  G PG PG FG   + 
Sbjct: 151  GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 515  VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 563
             P GP G  G  V G +G  G  GL GPPGPPG       GP  RT   G+KG  G  G 
Sbjct: 210  GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 564  PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618
            PG  G  G PG +     GA G+ GL G PG  G PG PG  G  G     GF  + G  
Sbjct: 270  PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326

Query: 619  GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 666
            G      +   G  GPPG  G          KGD G PG P   GA+G  G  G PG PG
Sbjct: 327  G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381

Query: 667  LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 712
             PG  R G+ G  G  G +GS+GE+G PGKD +G             PG PGPPGPPG +
Sbjct: 382  SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441

Query: 713  VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 744
            V+     G                                +PGP G PG  G  G  G  
Sbjct: 442  VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501

Query: 745  GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 796
            G  G+ G +GSPG  G  G PG  F    GA G P  KG KGE        G  G PG  
Sbjct: 502  GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559

Query: 797  GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 853
            G+PG KG  G PG PG  G+ G KGE    GE GD     G  G PG PG PGP GP G 
Sbjct: 560  GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615

Query: 854  PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 906
            P Y      E    G  G+PG  GPPG  G +GE+       GPPGPPG       Q   
Sbjct: 616  PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673

Query: 907  EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 959
             + G  G  GD G  G  GEP   G  G   PGPPGP G +G+P      G PG  GE  
Sbjct: 674  GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730

Query: 960  IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1006
            + G+PG PG +G P +   G  G PG PG             PG P  PG P  +   + 
Sbjct: 731  LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788

Query: 1007 GPPGPPGPPGPPGTMG 1022
            GP G PG PGPPG  G
Sbjct: 789  GPRGDPGQPGPPGEQG 804



 Score =  404 bits (1038), Expect = e-112
 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%)

Query: 436  DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491
            DKG    D   GE+G  G  GPPG PG                GF        GP G PG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73

Query: 492  PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 547
            P GP G PGLPG  G  GV   S +PG     GLPG PG  GP G  G+PG  G  G +G
Sbjct: 74   PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133

Query: 548  PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 602
             PG  G  G  G  GA G KG KGAP         A+G+ GL GAPGP G PGPPG PGP
Sbjct: 134  FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193

Query: 603  PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 636
             GP  P GF    G+ GP        +               GP GPPG           
Sbjct: 194  VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253

Query: 637  ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 682
               L G KGD G  G PG  G           E GA G PG  G PG++G+ G  G +G 
Sbjct: 254  RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313

Query: 683  RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 740
            +G+RG  G  G+DG+ GQ G  GPPG  GP  Y    Q+      PGP G  G  G  GP
Sbjct: 314  KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373

Query: 741  AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 791
            +GP G  GS G      RG+PG  G KG  G    P   A+G    P   G+ G PG  G
Sbjct: 374  SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433

Query: 792  PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 832
            PPGP G    R G  G+ G PG  G PG+ G+ G KGEPG                    
Sbjct: 434  PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 833  -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 887
              G++G+PG  G  G  G PG+P         +  PG PG PG QG PG KG KGE    
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546

Query: 888  ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 935
               VG PG PG      +   D +     +KG  G +G+   +G+KG++G PG  G  GS
Sbjct: 547  EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606

Query: 936  SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 973
              PGP GP GP GY              PG PGP GE+  RG+       PGPPGP GPP
Sbjct: 607  --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 974  GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1023
            G  + G QGPPG P   G  G P  PGP  +     I  PGPPGP G  G PGT G+
Sbjct: 665  G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719



 Score =  385 bits (990), Expect = e-106
 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%)

Query: 272  PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331
            P  P PP    PP   G   E  R             GAQ LPG + +    G     G 
Sbjct: 794  PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837

Query: 332  RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 384
            +   G       G  G+ G PG+PG  G  GP G    PG PG+  P    G  G  +  
Sbjct: 838  KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895

Query: 385  VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 438
             PG  GPPGPPG  GTPG+ G PG PG  G+ G  G +G  G  G+ GP       GDKG
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 439  DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 492
            +PG+ G  G PG +G  G PG                G  G L+ L GP G PGP     
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000

Query: 493  ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 536
                PG PG+ G+PG  G  G+  S   G  G  G PGR G PG PG+            
Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058

Query: 537  -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 590
                 PGPPGP G  G PG  G+KG +G+ G PGH G  G  G  G+ G  GL G PGP 
Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118

Query: 591  -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 628
                        GPPG  GPPG PG PG P         G D + G  G    T   R+ 
Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178

Query: 629  DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 674
             GP+G PG  G KGD   PG PGLPG KG +G          +G PG PGLPG    G  
Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238

Query: 675  GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 721
            G +GP G RGS G  G PG  G          G  G PGP GPPG    +          
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298

Query: 722  VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 776
               +PGP G PGF GFPG  G KGN G  G  G PGP G KG PG     D G L     
Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356

Query: 777  --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 825
               P   G  GEPG +G PGP G PG           G+ G PG PG  G  G KG KGE
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416

Query: 826  PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 866
            PG A    G  G+PG  G  G  G P T      VF   S+
Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453



 Score =  338 bits (868), Expect = 2e-92
 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%)

Query: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300
            G D  G  G++GS      +    E G   +   P  P +  PP   G          + 
Sbjct: 845  GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901

Query: 301  EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 347
                  + G     GS  +    G   TPG + ++G            + G KGEPG+  
Sbjct: 902  PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961

Query: 348  ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 393
                PG  G  G PG P L G  GLP P  P GP G          P L+ +PG  G  G
Sbjct: 962  FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 394  PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 433
             PG  G       PGR G PG PG  G              +PG  GP G PG PGD+G 
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081

Query: 434  KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492
            KG+ G PG  G  GP GP+G PG PG      K         G  GDL   +G +G  GP
Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132

Query: 493  PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 541
            PG   PPG+PG PG PG  G+        +PGPAG  G  G      GP G PG  G  G
Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192

Query: 542  PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 596
              G  G PG  G+KG++G+AG  G  G +G PGP G  G     ++G  G PG  G PG 
Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252

Query: 597  PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 650
            PGPPGPPG  +     D    G P         GP+GPPG       PG  G PG PGLP
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303

Query: 651  GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 706
            G +G+ G  G PG  G    PG  G  GP GP G +G  G +GDPG    +  PG PGPP
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363

Query: 707  GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 763
            G PG               PG +G PG  G PG   P GP+G  G  G+ G+PGP GEKG
Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 764  EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 807
              GS   P     GPA  G+ G PG +G  G  G P      GF
Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  276 bits (706), Expect = 1e-73
 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%)

Query: 567  KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626
            KG     G  G +GE G  G PG  G  G  GP G PGP  P GF  + G  G       
Sbjct: 36   KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88

Query: 627  SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 674
             + G +G  GLPG  G PG+PG PG  G  G  GVPG         FPGLP   G  GI 
Sbjct: 89   -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147

Query: 675  GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734
            G  G KG +G+  ++ D   D  G PGLPG                     PGP+G PG 
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187

Query: 735  AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 794
             GFPGP GP G  G  G  G+ GP+G KG  G         +G   KG +G  G  GPPG
Sbjct: 188  PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239

Query: 795  PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 835
            P G                G KG+ G  G PG PG +GL GE     KG PGD     G+
Sbjct: 240  PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295

Query: 836  RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895
            +G PG  G PG PG  G               G  G PG  G  G KG KG++GPPG  G
Sbjct: 296  QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342

Query: 896  QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 953
              P ++     E KG++G  G  G +G RG  G  G  G  +PG PG   PG RG PG P
Sbjct: 343  --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397

Query: 954  GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1005
            G KG +  RG+PG    G  G PG  G  G  G PGPPGPPG   F    PG H      
Sbjct: 398  GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451

Query: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATR 1033
             G PG  G PG PG  G      L  T+
Sbjct: 452  -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478



 Score =  168 bits (426), Expect = 3e-41
 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%)

Query: 766  GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 816
            G +    G       KG KGE GF GPP         GP G PG +G  GFPG PG  G 
Sbjct: 30   GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89

Query: 817  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 853
             G++G  G PG +    G  G+PG PG  GP                  PG PGT     
Sbjct: 90   KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 854  -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899
                         P  + ++  ++   PG PG PG QG PGP G  G VGPPGPPG F F
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 900  DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 951
                     KG  G+R   G KGERG  G        L GPPGPP        GP     
Sbjct: 206  PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256

Query: 952  IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1010
            + G KG+    G+PGPPGP G PG  Y   +G PG PG  G P   G        PG  G
Sbjct: 257  LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312

Query: 1011 PPGPPGPPGTMG 1022
              G  G PG MG
Sbjct: 313  VKGNRGFPGLMG 324


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  512 bits (1318), Expect = e-144
 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G  GD G         LR + G      +P  P V   P   G   E + S E  +Q   
Sbjct: 551  GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 360
               G+   PG        G    PG G   E GL+G +G PG PGPPG AGP G    S 
Sbjct: 599  GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 413
             +PGPPG P      GP G      PGPQGPPG PG        G PG DGEPG PG   
Sbjct: 653  PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 414  -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 457
             G PG  G QGFPGT               PG  G  G KG+P V   G PG  G PG  
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 458  GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 517
            G S  H ++    + G       E L GPRG PG PGPPG  G PG        +  +PG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 518  PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572
              GL G  GR G   P G PG+PG    G PG  G PG  G +G +G  G  G+ G+ G 
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 573  PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 628
             GP G  G  G+ G PG  GPPGPPG PG PG    PG+P G     G+ G     A+  
Sbjct: 882  LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935

Query: 629  DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682
             G +G PG      + G KG+PG+ G  G  GE G  GVPG PGL G +G+ GP GP G 
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 683  RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 737
            RG  G  G+PG+ G+ G PG  G  G PG     S+     L  PG  GRPG  G     
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 738  -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 772
                         PGP GP G+      +G KGE G PGP G       +G PGS  SP 
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 773  -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824
              G  GP         KG  G PG RGPPG  G PG  G +G  G  GR G+ G  GEKG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 825  EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 873
            E G      G RG PG  G  G  G PG P       A               PGPPGLP
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 874  G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925
            G        N+GPPG +G+ G  GPPGPPG          + + G KGD+G  G  G +G
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280

Query: 926  EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 984
             PG  G  G     PPG  G  G PG+PGP+G+   +G PG  G +G PG  + G  GPP
Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333

Query: 985  GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1022
            GP GP GPP   G     + IS+PG PGPPG PG PG  G
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373



 Score =  480 bits (1235), Expect = e-135
 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%)

Query: 243  DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302
            D+    GD G+         R   G +  P +P  P  + P L G       +  + E  
Sbjct: 348  DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407

Query: 303  TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 362
                   A   PGS   +   G   +PG     G +  +KG PG  G PG  G PG P +
Sbjct: 408  RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465

Query: 363  PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419
             GP   PGL C   P  P  P L  +PG  G  G PGR G  G  G PG PG  G PG  
Sbjct: 466  DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524

Query: 420  GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 465
               GFPG  GD G KG+K             GDPG+ G+ G  G  G PG PG       
Sbjct: 525  --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575

Query: 466  LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 521
                 ++G  G  G+L AL G +G  GPPG PG PG PG  G     G      PG  G 
Sbjct: 576  -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629

Query: 522  PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568
             GVPG  GPPG              PG PGPPGPPG  GP G  G  GSLG+ G PG  G
Sbjct: 630  QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 569  SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 615
              G         PGP G +G+ G  G  G  G PG  G PG PG PGLP    +      
Sbjct: 690  PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 616  -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 670
             G G P +   R   G  G    PGLPGL G PG  GL G +G+ G  G PG  G PGR 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 671  ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 718
                       G+ G +G +G RG  G KGDPG  G+ + G PG  G PG   +  E   
Sbjct: 810  IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869

Query: 719  --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 755
                    +  +L  PG +G  G  GFP   GP GP GN G+            KG+RG+
Sbjct: 870  LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 756  PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 795
            PG KGE+G+ G+    +              G A  P +KG +G P      G +G PGP
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 796  YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 847
             G PG +G++G  G PG PG+ G+ G  G  G         +LGF G  G PG PG  G 
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 848  PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 901
             G  G P Y     +E +RPGPPG  G+ G PG  G KGE+G PGPPG            
Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 902  LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 939
                  + G+ G  GD G K         G RG PG  GF GS              +PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 940  PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 988
            P G          PPGPRG PG  G KG+  RG PG PG  G  G +G  G +GP G  G
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222

Query: 989  PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1020
             PGPP  PG        +R      G PG PGPPGPPG+
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261



 Score =  470 bits (1209), Expect = e-132
 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 365
            G + LPG      + G     G +   G  GL G  G PG+PG PG  GP G   +PG  
Sbjct: 67   GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126

Query: 366  --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 405
                    PGLP     LG P  P    + G +G P           G PG  G PG  G
Sbjct: 127  GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183

Query: 406  EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 462
             PG PG  G  G  GP GF G PG +GP+G KG  G   +G +G  G +G  GPPGP   
Sbjct: 184  LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240

Query: 463  HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 505
                  + + G     DL+  +G +G    PGPPGP              PG PGL G+P
Sbjct: 241  -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299

Query: 506  GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 537
            G+ GV     S  V G  G PG+ G +         GPPGF                G P
Sbjct: 300  GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359

Query: 538  GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574
            GPPGP                       PG  G PG  G KGS GE G PG K + G PG
Sbjct: 360  GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418

Query: 575  PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 623
              G  G  GL G+PGP GPP       GPPG  G PG    PG+P G D  +G  G   +
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477

Query: 624  TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677
                  GP G PGLPGL G  G+P      GL G+ G  G  G+PGFPG PG +G  G +
Sbjct: 478  QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 678  GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 723
            G K             GD G RG+ G  G DG+ G PG+ G PGP G +    E+     
Sbjct: 538  GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595

Query: 724  SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 770
               GP G PG  G PGPAGP G             G++G  G+PGP GE G  G  S+ +
Sbjct: 596  ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 771  PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 822
            P  G  GP   G  G PG +GPPG  G  G  G+ G PG  G PG+ G+        KG+
Sbjct: 653  PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710

Query: 823  KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 864
            +G PG   SLG     G  G+PG PG PG         PG PGTP +     +S    E 
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 865  SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 916
              PG PGLPG  G  G  G +G+ G PGPPG+       +E          + G KG +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 917  DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 974
              G+ G +G+PG  G   S  PG  G PG  G+ G  GP G+  RG PG PG  GPPG  
Sbjct: 831  RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888

Query: 975  --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
              IG  G  G  GPPGPPG P  PG  R +  +PG  G  G PG  G  G
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937



 Score =  454 bits (1168), Expect = e-127
 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%)

Query: 337  GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 395
            G KG+KGE G PGPPG          PG  G   P    GP GP     +PG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93

Query: 396  GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 454
            G  G PG  G PG P   G PG+TGP G  G PG  G KG++G PG+ G  G PG  G  
Sbjct: 94   GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150

Query: 455  GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 514
            G  G      K   I+++  G  G L    GP+G PGPPG PG  G PG PG FG   + 
Sbjct: 151  GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 515  VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 563
             P GP G  G  V G +G  G  GL GPPGPPG       GP  RT   G+KG  G  G 
Sbjct: 210  GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 564  PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618
            PG  G  G PG +     GA G+ GL G PG  G PG PG  G  G     GF  + G  
Sbjct: 270  PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326

Query: 619  GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 666
            G      +   G  GPPG  G          KGD G PG P   GA+G  G  G PG PG
Sbjct: 327  G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381

Query: 667  LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 712
             PG  R G+ G  G  G +GS+GE+G PGKD +G             PG PGPPGPPG +
Sbjct: 382  SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441

Query: 713  VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 744
            V+     G                                +PGP G PG  G  G  G  
Sbjct: 442  VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501

Query: 745  GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 796
            G  G+ G +GSPG  G  G PG  F    GA G P  KG KGE        G  G PG  
Sbjct: 502  GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559

Query: 797  GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 853
            G+PG KG  G PG PG  G+ G KGE    GE GD     G  G PG PG PGP GP G 
Sbjct: 560  GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615

Query: 854  PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 906
            P Y      E    G  G+PG  GPPG  G +GE+       GPPGPPG       Q   
Sbjct: 616  PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673

Query: 907  EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 959
             + G  G  GD G  G  GEP   G  G   PGPPGP G +G+P      G PG  GE  
Sbjct: 674  GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730

Query: 960  IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1006
            + G+PG PG +G P +   G  G PG PG             PG P  PG P  +   + 
Sbjct: 731  LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788

Query: 1007 GPPGPPGPPGPPGTMG 1022
            GP G PG PGPPG  G
Sbjct: 789  GPRGDPGQPGPPGEQG 804



 Score =  404 bits (1038), Expect = e-112
 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%)

Query: 436  DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491
            DKG    D   GE+G  G  GPPG PG                GF        GP G PG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73

Query: 492  PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 547
            P GP G PGLPG  G  GV   S +PG     GLPG PG  GP G  G+PG  G  G +G
Sbjct: 74   PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133

Query: 548  PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 602
             PG  G  G  G  GA G KG KGAP         A+G+ GL GAPGP G PGPPG PGP
Sbjct: 134  FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193

Query: 603  PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 636
             GP  P GF    G+ GP        +               GP GPPG           
Sbjct: 194  VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253

Query: 637  ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 682
               L G KGD G  G PG  G           E GA G PG  G PG++G+ G  G +G 
Sbjct: 254  RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313

Query: 683  RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 740
            +G+RG  G  G+DG+ GQ G  GPPG  GP  Y    Q+      PGP G  G  G  GP
Sbjct: 314  KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373

Query: 741  AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 791
            +GP G  GS G      RG+PG  G KG  G    P   A+G    P   G+ G PG  G
Sbjct: 374  SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433

Query: 792  PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 832
            PPGP G    R G  G+ G PG  G PG+ G+ G KGEPG                    
Sbjct: 434  PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 833  -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 887
              G++G+PG  G  G  G PG+P         +  PG PG PG QG PG KG KGE    
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546

Query: 888  ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 935
               VG PG PG      +   D +     +KG  G +G+   +G+KG++G PG  G  GS
Sbjct: 547  EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606

Query: 936  SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 973
              PGP GP GP GY              PG PGP GE+  RG+       PGPPGP GPP
Sbjct: 607  --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 974  GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1023
            G  + G QGPPG P   G  G P  PGP  +     I  PGPPGP G  G PGT G+
Sbjct: 665  G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719



 Score =  385 bits (990), Expect = e-106
 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%)

Query: 272  PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331
            P  P PP    PP   G   E  R             GAQ LPG + +    G     G 
Sbjct: 794  PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837

Query: 332  RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 384
            +   G       G  G+ G PG+PG  G  GP G    PG PG+  P    G  G  +  
Sbjct: 838  KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895

Query: 385  VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 438
             PG  GPPGPPG  GTPG+ G PG PG  G+ G  G +G  G  G+ GP       GDKG
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 439  DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 492
            +PG+ G  G PG +G  G PG                G  G L+ L GP G PGP     
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000

Query: 493  ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 536
                PG PG+ G+PG  G  G+  S   G  G  G PGR G PG PG+            
Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058

Query: 537  -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 590
                 PGPPGP G  G PG  G+KG +G+ G PGH G  G  G  G+ G  GL G PGP 
Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118

Query: 591  -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 628
                        GPPG  GPPG PG PG P         G D + G  G    T   R+ 
Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178

Query: 629  DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 674
             GP+G PG  G KGD   PG PGLPG KG +G          +G PG PGLPG    G  
Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238

Query: 675  GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 721
            G +GP G RGS G  G PG  G          G  G PGP GPPG    +          
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298

Query: 722  VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 776
               +PGP G PGF GFPG  G KGN G  G  G PGP G KG PG     D G L     
Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356

Query: 777  --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 825
               P   G  GEPG +G PGP G PG           G+ G PG PG  G  G KG KGE
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416

Query: 826  PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 866
            PG A    G  G+PG  G  G  G P T      VF   S+
Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453



 Score =  338 bits (868), Expect = 2e-92
 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%)

Query: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300
            G D  G  G++GS      +    E G   +   P  P +  PP   G          + 
Sbjct: 845  GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901

Query: 301  EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 347
                  + G     GS  +    G   TPG + ++G            + G KGEPG+  
Sbjct: 902  PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961

Query: 348  ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 393
                PG  G  G PG P L G  GLP P  P GP G          P L+ +PG  G  G
Sbjct: 962  FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 394  PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 433
             PG  G       PGR G PG PG  G              +PG  GP G PG PGD+G 
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081

Query: 434  KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492
            KG+ G PG  G  GP GP+G PG PG      K         G  GDL   +G +G  GP
Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132

Query: 493  PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 541
            PG   PPG+PG PG PG  G+        +PGPAG  G  G      GP G PG  G  G
Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192

Query: 542  PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 596
              G  G PG  G+KG++G+AG  G  G +G PGP G  G     ++G  G PG  G PG 
Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252

Query: 597  PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 650
            PGPPGPPG  +     D    G P         GP+GPPG       PG  G PG PGLP
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303

Query: 651  GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 706
            G +G+ G  G PG  G    PG  G  GP GP G +G  G +GDPG    +  PG PGPP
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363

Query: 707  GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 763
            G PG               PG +G PG  G PG   P GP+G  G  G+ G+PGP GEKG
Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 764  EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 807
              GS   P     GPA  G+ G PG +G  G  G P      GF
Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  276 bits (706), Expect = 1e-73
 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%)

Query: 567  KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626
            KG     G  G +GE G  G PG  G  G  GP G PGP  P GF  + G  G       
Sbjct: 36   KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88

Query: 627  SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 674
             + G +G  GLPG  G PG+PG PG  G  G  GVPG         FPGLP   G  GI 
Sbjct: 89   -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147

Query: 675  GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734
            G  G KG +G+  ++ D   D  G PGLPG                     PGP+G PG 
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187

Query: 735  AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 794
             GFPGP GP G  G  G  G+ GP+G KG  G         +G   KG +G  G  GPPG
Sbjct: 188  PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239

Query: 795  PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 835
            P G                G KG+ G  G PG PG +GL GE     KG PGD     G+
Sbjct: 240  PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295

Query: 836  RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895
            +G PG  G PG PG  G               G  G PG  G  G KG KG++GPPG  G
Sbjct: 296  QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342

Query: 896  QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 953
              P ++     E KG++G  G  G +G RG  G  G  G  +PG PG   PG RG PG P
Sbjct: 343  --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397

Query: 954  GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1005
            G KG +  RG+PG    G  G PG  G  G  G PGPPGPPG   F    PG H      
Sbjct: 398  GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451

Query: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATR 1033
             G PG  G PG PG  G      L  T+
Sbjct: 452  -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478



 Score =  168 bits (426), Expect = 3e-41
 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%)

Query: 766  GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 816
            G +    G       KG KGE GF GPP         GP G PG +G  GFPG PG  G 
Sbjct: 30   GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89

Query: 817  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 853
             G++G  G PG +    G  G+PG PG  GP                  PG PGT     
Sbjct: 90   KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 854  -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899
                         P  + ++  ++   PG PG PG QG PGP G  G VGPPGPPG F F
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 900  DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 951
                     KG  G+R   G KGERG  G        L GPPGPP        GP     
Sbjct: 206  PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256

Query: 952  IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1010
            + G KG+    G+PGPPGP G PG  Y   +G PG PG  G P   G        PG  G
Sbjct: 257  LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312

Query: 1011 PPGPPGPPGTMG 1022
              G  G PG MG
Sbjct: 313  VKGNRGFPGLMG 324


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  512 bits (1318), Expect = e-144
 Identities = 357/880 (40%), Positives = 410/880 (46%), Gaps = 160/880 (18%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G  GD G         LR + G      +P  P V   P   G   E + S E  +Q   
Sbjct: 551  GVPGDPG---------LRGQPGRKGLDGIPGTPGVKGLP---GPKGELALSGEKGDQGPP 598

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPG-GRVKEGGLKGQKGEPGVPGPPGRAGPPG----SP 360
               G+   PG        G    PG G   E GL+G +G PG PGPPG AGP G    S 
Sbjct: 599  GDPGSPGSPGPA------GPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGR------DGTPGRDGEPGDPGED- 413
             +PGPPG P      GP G      PGPQGPPG PG        G PG DGEPG PG   
Sbjct: 653  PVPGPPGPP------GPPGH-----PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF 701

Query: 414  -GKPGDTGPQGFPGT---------------PGDVGPKGDKGDPGVGERGPPGPQGPPGPP 457
             G PG  G QGFPGT               PG  G  G KG+P V   G PG  G PG  
Sbjct: 702  PGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGER 761

Query: 458  GPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPG 517
            G S  H ++    + G       E L GPRG PG PGPPG  G PG        +  +PG
Sbjct: 762  GNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 518  PAGLPGVPGREG---PPGFPGLPG--PPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572
              GL G  GR G   P G PG+PG    G PG  G PG  G +G +G  G  G+ G+ G 
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 573  PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG----PGLPAGFDDMEGSGGPFWSTARSA 628
             GP G  G  G+ G PG  GPPGPPG PG PG    PG+P G     G+ G     A+  
Sbjct: 882  LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP-GVKGQRGTPG-----AKGE 935

Query: 629  DGPQGPPG------LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGD 682
             G +G PG      + G KG+PG+ G  G  GE G  GVPG PGL G +G+ GP GP G 
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 683  RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGF---- 737
            RG  G  G+PG+ G+ G PG  G  G PG     S+     L  PG  GRPG  G     
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPG-----SKGKRGTLGFPGRAGRPGLPGIHGLQ 1050

Query: 738  -------------PGPAGPKGN------LGSKGERGSPGPKGE------KGEPGSIFSPD 772
                         PGP GP G+      +G KGE G PGP G       +G PGS  SP 
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 773  -GGALGP-------AQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG 824
              G  GP         KG  G PG RGPPG  G PG  G +G  G  GR G+ G  GEKG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 825  EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR-----------PGPPGLP 873
            E G      G RG PG  G  G  G PG P       A               PGPPGLP
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 874  G--------NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERG 925
            G        N+GPPG +G+ G  GPPGPPG          + + G KGD+G  G  G +G
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPG----------SHVIGIKGDKGSMGHPGPKG 1280

Query: 926  EPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPP 984
             PG  G  G     PPG  G  G PG+PGP+G+   +G PG  G +G PG  + G  GPP
Sbjct: 1281 PPGTAGDMG-----PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--FLGSIGPP 1333

Query: 985  GPPGPPGPPSFPGPHR--QTISVPGPPGPPGPPGPPGTMG 1022
            GP GP GPP   G     + IS+PG PGPPG PG PG  G
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373



 Score =  480 bits (1235), Expect = e-135
 Identities = 351/939 (37%), Positives = 415/939 (44%), Gaps = 186/939 (19%)

Query: 243  DSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQ 302
            D+    GD G+         R   G +  P +P  P  + P L G       +  + E  
Sbjct: 348  DTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407

Query: 303  TTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCL 362
                   A   PGS   +   G   +PG     G +  +KG PG  G PG  G PG P +
Sbjct: 408  RP--GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465

Query: 363  PGP---PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDT 419
             GP   PGL C   P  P  P L  +PG  G  G PGR G  G  G PG PG  G PG  
Sbjct: 466  DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF- 524

Query: 420  GPQGFPGTPGDVGPKGDK-------------GDPGV-GERGPPGPQGPPGPPGPSFRHDK 465
               GFPG  GD G KG+K             GDPG+ G+ G  G  G PG PG       
Sbjct: 525  --PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG------- 575

Query: 466  LTFIDMEG-SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRF---GVNSSDVPGPAGL 521
                 ++G  G  G+L AL G +G  GPPG PG PG PG  G     G      PG  G 
Sbjct: 576  -----VKGLPGPKGEL-ALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGT 629

Query: 522  PGVPGREGPPG-------------FPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKG 568
             GVPG  GPPG              PG PGPPGPPG  GP G  G  GSLG+ G PG  G
Sbjct: 630  QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 569  SKGA--------PGPAGARGESGLAGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME---- 615
              G         PGP G +G+ G  G  G  G PG  G PG PG PGLP    +      
Sbjct: 690  PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 616  -GSGGPFWSTARSADGPQGP---PGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR- 670
             G G P +   R   G  G    PGLPGL G PG  GL G +G+ G  G PG  G PGR 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 671  ----------EGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQ-- 718
                       G+ G +G +G RG  G KGDPG  G+ + G PG  G PG   +  E   
Sbjct: 810  IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869

Query: 719  --------DGSVLSVPGPEGRPGFAGFP---GPAGPKGNLGS------------KGERGS 755
                    +  +L  PG +G  G  GFP   GP GP GN G+            KG+RG+
Sbjct: 870  LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 756  PGPKGEKGEPGSIFSPD--------------GGALGPAQKGAKGEP------GFRGPPGP 795
            PG KGE+G+ G+    +              G A  P +KG +G P      G +G PGP
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 796  YGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF-GMRGMPGPPGPPGP 847
             G PG +G++G  G PG PG+ G+ G  G  G         +LGF G  G PG PG  G 
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 848  PGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQF------PFDF 901
             G  G P Y     +E +RPGPPG  G+ G PG  G KGE+G PGPPG            
Sbjct: 1050 QGDKGEPGY-----SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 902  LQLEAEMKGEKGDRGDAGQK---------GERGEPGGGGFFGS-------------SLPG 939
                  + G+ G  GD G K         G RG PG  GF GS              +PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 940  PPG----------PPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPG 988
            P G          PPGPRG PG  G KG+  RG PG PG  G  G +G  G +GP G  G
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGD--RGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222

Query: 989  PPGPPSFPGP-------HRQTISVPGPPGPPGPPGPPGT 1020
             PGPP  PG        +R      G PG PGPPGPPG+
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261



 Score =  470 bits (1209), Expect = e-132
 Identities = 340/890 (38%), Positives = 403/890 (45%), Gaps = 195/890 (21%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGP- 365
            G + LPG      + G     G +   G  GL G  G PG+PG PG  GP G   +PG  
Sbjct: 67   GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCS 126

Query: 366  --------PGLPCPVSPLG-PAGPALQTVPGPQGPP-----------GPPGRDGTPGRDG 405
                    PGLP     LG P  P    + G +G P           G PG  G PG  G
Sbjct: 127  GSKGEQGFPGLP---GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183

Query: 406  EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPG---VGERGPPGPQGPPGPPGPSFR 462
             PG PG  G  G  GP GF G PG +GP+G KG  G   +G +G  G +G  GPPGP   
Sbjct: 184  LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP--- 240

Query: 463  HDKLTFIDMEGSGFGGDLEALRGPRGF---PGPPGP--------------PGVPGLPGEP 505
                  + + G     DL+  +G +G    PGPPGP              PG PGL G+P
Sbjct: 241  -PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKP 299

Query: 506  GRFGV----NSSDVPGPAGLPGVPGRE---------GPPGF---------------PGLP 537
            G+ GV     S  V G  G PG+ G +         GPPGF                G P
Sbjct: 300  GKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTP 359

Query: 538  GPPGP-----------------------PGREGPPGRTGQKGSLGEAGAPGHKGSKGAPG 574
            GPPGP                       PG  G PG  G KGS GE G PG K + G PG
Sbjct: 360  GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPG 418

Query: 575  PAGARGESGLAGAPGPAGPP-------GPPGPPGPPG----PGLPAGFDDMEGSGGPFWS 623
              G  G  GL G+PGP GPP       GPPG  G PG    PG+P G D  +G  G   +
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP-GVDGPKGEPGLLCT 477

Query: 624  TARSADGPQGPPGLPGLKGDPGVP------GLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677
                  GP G PGLPGL G  G+P      GL G+ G  G  G+PGFPG PG +G  G +
Sbjct: 478  QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 678  GPK-------------GDRGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSEQDGSVL 723
            G K             GD G RG+ G  G DG+ G PG+ G PGP G +    E+     
Sbjct: 538  GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ-- 595

Query: 724  SVPGPEGRPGFAGFPGPAGPKGN-----------LGSKGERGSPGPKGEKGEPG--SIFS 770
               GP G PG  G PGPAGP G             G++G  G+PGP GE G  G  S+ +
Sbjct: 596  ---GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 771  PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL--------KGE 822
            P  G  GP   G  G PG +GPPG  G  G  G+ G PG  G PG+ G+        KG+
Sbjct: 653  PVPGPPGP--PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710

Query: 823  KGEPG-DASLG----FGMRGMPGPPGPPGP--------PGPPGTPVY-----DSNVFAES 864
            +G PG   SLG     G  G+PG PG PG         PG PGTP +     +S    E 
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 865  SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAE--------MKGEKGDRG 916
              PG PGLPG  G  G  G +G+ G PGPPG+       +E          + G KG +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 917  DAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPG-- 974
              G+ G +G+PG  G   S  PG  G PG  G+ G  GP G+  RG PG PG  GPPG  
Sbjct: 831  RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ--RGYPGNPGILGPPGED 888

Query: 975  --IGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
              IG  G  G  GPPGPPG P  PG  R +  +PG  G  G PG  G  G
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPG-QRGSPGIPGVKGQRGTPGAKGEQG 937



 Score =  454 bits (1168), Expect = e-127
 Identities = 322/796 (40%), Positives = 364/796 (45%), Gaps = 144/796 (18%)

Query: 337  GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP-ALQTVPGPQGPPGPP 395
            G KG+KGE G PGPPG          PG  G   P    GP GP     +PG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGS---------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93

Query: 396  GRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPP 454
            G  G PG  G PG P   G PG+TGP G  G PG  G KG++G PG+ G  G PG  G  
Sbjct: 94   GISGLPGFSGSPGLP---GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA 150

Query: 455  GPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD 514
            G  G      K   I+++  G  G L    GP+G PGPPG PG  G PG PG FG   + 
Sbjct: 151  GLKGQKGAPAKEEDIELDAKGDPG-LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 515  VP-GPAGLPG--VPGREGPPGFPGLPGPPGPPGR-----EGPPGRT---GQKGSLGEAGA 563
             P GP G  G  V G +G  G  GL GPPGPPG       GP  RT   G+KG  G  G 
Sbjct: 210  GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 564  PGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSG 618
            PG  G  G PG +     GA G+ GL G PG  G PG PG  G  G     GF  + G  
Sbjct: 270  PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG---NRGFPGLMGED 326

Query: 619  GPFWSTARSADGPQGPPGLPG---------LKGDPGVPGLP---GAKGEVGADGVPGFPG 666
            G      +   G  GPPG  G          KGD G PG P   GA+G  G  G PG PG
Sbjct: 327  G-----IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPG 381

Query: 667  LPG--REGIAGPQGPKGDRGSRGEKGDPGKDGVGQ------------PGLPGPPGPPGPV 712
             PG  R G+ G  G  G +GS+GE+G PGKD +G             PG PGPPGPPG +
Sbjct: 382  SPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI 441

Query: 713  VYVSEQDG----------------------------SVLSVPGPEGRPGFAGFPGPAGPK 744
            V+     G                                +PGP G PG  G  G  G  
Sbjct: 442  VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501

Query: 745  GNLGSKGERGSPGPKGEKGEPGSIFSPDGGALG-PAQKGAKGEP-------GFRGPPGPY 796
            G  G+ G +GSPG  G  G PG  F    GA G P  KG KGE        G  G PG  
Sbjct: 502  GRQGAAGLKGSPGSPGNTGLPG--FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559

Query: 797  GRPGYKGEIGFPGRPGRPGMNGLKGE---KGEPGDASLGFGMRGMPGPPGPPGPPGPPGT 853
            G+PG KG  G PG PG  G+ G KGE    GE GD     G  G PG PG PGP GP G 
Sbjct: 560  GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQ----GPPGDPGSPGSPGPAGPAGP 615

Query: 854  PVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEV-------GPPGPPGQFPFDFLQLEA 906
            P Y      E    G  G+PG  GPPG  G +GE+       GPPGPPG       Q   
Sbjct: 616  PGYGPQ--GEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673

Query: 907  EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYP------GIPGPKGE-S 959
             + G  G  GD G  G  GEP   G  G   PGPPGP G +G+P      G PG  GE  
Sbjct: 674  GIPGSLGKCGDPGLPGPDGEP---GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730

Query: 960  IRGQPGPPGPQGPPGIGYEGRQGPPGPPGP------------PGPPSFPG-PHRQTISVP 1006
            + G+PG PG +G P +   G  G PG PG             PG P  PG P  +   + 
Sbjct: 731  LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE--GLD 788

Query: 1007 GPPGPPGPPGPPGTMG 1022
            GP G PG PGPPG  G
Sbjct: 789  GPRGDPGQPGPPGEQG 804



 Score =  404 bits (1038), Expect = e-112
 Identities = 289/717 (40%), Positives = 332/717 (46%), Gaps = 161/717 (22%)

Query: 436  DKG----DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPG 491
            DKG    D   GE+G  G  GPPG PG                GF        GP G PG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQK--------------GF-------TGPEGLPG 73

Query: 492  PPGPPGVPGLPGEPGRFGVNS-SDVPG---PAGLPGVPGREGPPGFPGLPGPPGPPGREG 547
            P GP G PGLPG  G  GV   S +PG     GLPG PG  GP G  G+PG  G  G +G
Sbjct: 74   PQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQG 133

Query: 548  PPGRTGQKGSLGEAGAPGHKGSKGAPGPA-----GARGESGLAGAPGPAGPPGPPGPPGP 602
             PG  G  G  G  GA G KG KGAP         A+G+ GL GAPGP G PGPPG PGP
Sbjct: 134  FPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGP 193

Query: 603  PGPGLPAGFDDMEGSGGPFWSTARSAD---------------GPQGPPG----------- 636
             GP  P GF    G+ GP        +               GP GPPG           
Sbjct: 194  VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDN 253

Query: 637  ---LPGLKGDPGVPGLPGAKG-----------EVGADGVPGFPGLPGREGIAGPQGPKGD 682
               L G KGD G  G PG  G           E GA G PG  G PG++G+ G  G +G 
Sbjct: 254  RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313

Query: 683  RGSRGEKGDPGKDGV-GQPGLPGPPGPPGPVVYVSE-QDGSVLSVPGPEGRPGFAGFPGP 740
            +G+RG  G  G+DG+ GQ G  GPPG  GP  Y    Q+      PGP G  G  G  GP
Sbjct: 314  KGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGP 373

Query: 741  AGPKGNLGSKGE-----RGSPGPKGEKGEPGSIFSPDGGALG----PAQKGAKGEPGFRG 791
            +GP G  GS G      RG+PG  G KG  G    P   A+G    P   G+ G PG  G
Sbjct: 374  SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433

Query: 792  PPGPYG----RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLG--------------- 832
            PPGP G    R G  G+ G PG  G PG+ G+ G KGEPG                    
Sbjct: 434  PPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493

Query: 833  -FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGE---- 887
              G++G+PG  G  G  G PG+P         +  PG PG PG QG PG KG KGE    
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSP-------GNTGLPGFPGFPGAQGDPGLKGEKGETLQP 546

Query: 888  ---VGPPGPPG------QFPFDFLQLEAEMKGEKGDRGD---AGQKGERGEPGGGGFFGS 935
               VG PG PG      +   D +     +KG  G +G+   +G+KG++G PG  G  GS
Sbjct: 547  EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606

Query: 936  SLPGPPGPPGPRGY--------------PGIPGPKGES-IRGQ-------PGPPGPQGPP 973
              PGP GP GP GY              PG PGP GE+  RG+       PGPPGP GPP
Sbjct: 607  --PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 974  GIGYEGRQGPPGPP---GPPGPPSFPGPHRQT----ISVPGPPGPPGPPGPPGTMGA 1023
            G  + G QGPPG P   G  G P  PGP  +     I  PGPPGP G  G PGT G+
Sbjct: 665  G--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719



 Score =  385 bits (990), Expect = e-106
 Identities = 274/701 (39%), Positives = 309/701 (44%), Gaps = 147/701 (20%)

Query: 272  PRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGG 331
            P  P PP    PP   G   E  R             GAQ LPG + +    G     G 
Sbjct: 794  PGQPGPPGEQGPP---GRCIEGPR-------------GAQGLPGLNGLKGQQGRRGKTGP 837

Query: 332  RVKEG-------GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT 384
            +   G       G  G+ G PG+PG  G  GP G    PG PG+  P    G  G  +  
Sbjct: 838  KGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG--MMG 895

Query: 385  VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPK------GDKG 438
             PG  GPPGPPG  GTPG+ G PG PG  G+ G  G +G  G  G+ GP       GDKG
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 439  DPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP----- 492
            +PG+ G  G PG +G  G PG                G  G L+ L GP G PGP     
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMP--------------GLKG-LKGLPGPAGPPGPRGDLG 1000

Query: 493  ----PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGL------------ 536
                PG PG+ G+PG  G  G+  S   G  G  G PGR G PG PG+            
Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058

Query: 537  -----PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP- 590
                 PGPPGP G  G PG  G+KG +G+ G PGH G  G  G  G+ G  GL G PGP 
Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118

Query: 591  -----------AGPPGPPGPPGPPG-PGLPA--------GFDDMEGSGGPFWSTA--RSA 628
                        GPPG  GPPG PG PG P         G D + G  G    T   R+ 
Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178

Query: 629  DGPQGPPGLPGLKGD---PGVPGLPGAKGEVG---------ADGVPGFPGLPGR--EGIA 674
             GP+G PG  G KGD   PG PGLPG KG +G          +G PG PGLPG    G  
Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238

Query: 675  GPQGPKGDRGSRGEKGDPGKDGV---------GQPGLPGPPGPPGPVVYVSEQDG----S 721
            G +GP G RGS G  G PG  G          G  G PGP GPPG    +          
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPG 1298

Query: 722  VLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGAL----- 776
               +PGP G PGF GFPG  G KGN G  G  G PGP G KG PG     D G L     
Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--VRGDPGTLKIISL 1356

Query: 777  --GPAQKGAKGEPGFRGPPGPYGRPGY---------KGEIGFPGRPGRPGMNGLKGEKGE 825
               P   G  GEPG +G PGP G PG           G+ G PG PG  G  G KG KGE
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416

Query: 826  PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR 866
            PG A    G  G+PG  G  G  G P T      VF   S+
Sbjct: 1417 PGPA----GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQ 1453



 Score =  338 bits (868), Expect = 2e-92
 Identities = 242/644 (37%), Positives = 286/644 (44%), Gaps = 119/644 (18%)

Query: 241  GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE 300
            G D  G  G++GS      +    E G   +   P  P +  PP   G          + 
Sbjct: 845  GLDRSGFPGETGSPGIPGHQ---GEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIG 901

Query: 301  EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGG-----------LKGQKGEPGV-- 347
                  + G     GS  +    G   TPG + ++G            + G KGEPG+  
Sbjct: 902  PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKG 961

Query: 348  ----PGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG----------PALQTVPGPQGPPG 393
                PG  G  G PG P L G  GLP P  P GP G          P L+ +PG  G  G
Sbjct: 962  FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 394  PPGRDGT------PGRDGEPGDPGEDG--------------KPGDTGPQGFPGTPGDVGP 433
             PG  G       PGR G PG PG  G              +PG  GP G PG PGD+G 
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081

Query: 434  KGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP 492
            KG+ G PG  G  GP GP+G PG PG      K         G  GDL   +G +G  GP
Sbjct: 1082 KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK--------PGPHGDL-GFKGIKGLLGP 1132

Query: 493  PG---PPGVPGLPGEPGRFGVNSSD----VPGPAGLPGVPGR----EGPPGFPGLPGPPG 541
            PG   PPG+PG PG PG  G+        +PGPAG  G  G      GP G PG  G  G
Sbjct: 1133 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192

Query: 542  PPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARG-----ESGLAGAPGPAGPPGP 596
              G  G PG  G+KG++G+AG  G  G +G PGP G  G     ++G  G PG  G PG 
Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252

Query: 597  PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGL------PGLKGDPGVPGLP 650
            PGPPGPPG  +     D    G P         GP+GPPG       PG  G PG PGLP
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHP---------GPKGPPGTAGDMGPPGRLGAPGTPGLP 1303

Query: 651  GAKGEVGADGVPGFPGL---PGREGIAGPQGPKGDRGSRGEKGDPGK-DGVGQPGLPGPP 706
            G +G+ G  G PG  G    PG  G  GP GP G +G  G +GDPG    +  PG PGPP
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPP 1363

Query: 707  GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPG---PAGPKGNLGSKGERGSPGPKGEKG 763
            G PG               PG +G PG  G PG   P GP+G  G  G+ G+PGP GEKG
Sbjct: 1364 GTPGE--------------PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 764  EPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGF 807
              GS   P     GPA  G+ G PG +G  G  G P      GF
Sbjct: 1410 NKGSKGEP-----GPA--GSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score =  276 bits (706), Expect = 1e-73
 Identities = 201/508 (39%), Positives = 230/508 (45%), Gaps = 106/508 (20%)

Query: 567  KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626
            KG     G  G +GE G  G PG  G  G  GP G PGP  P GF  + G  G       
Sbjct: 36   KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTG------- 88

Query: 627  SADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPG---------FPGLP---GREGIA 674
             + G +G  GLPG  G PG+PG PG  G  G  GVPG         FPGLP   G  GI 
Sbjct: 89   -SKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147

Query: 675  GPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGF 734
            G  G KG +G+  ++ D   D  G PGLPG                     PGP+G PG 
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPG--------------------APGPQGLPGP 187

Query: 735  AGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPG 794
             GFPGP GP G  G  G  G+ GP+G KG  G         +G   KG +G  G  GPPG
Sbjct: 188  PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGE------RVIG--HKGERGVKGLTGPPG 239

Query: 795  PYGR--------------PGYKGEIGFPGRPGRPGMNGLKGE-----KGEPGDASLGFGM 835
            P G                G KG+ G  G PG PG +GL GE     KG PGD     G+
Sbjct: 240  PPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDP----GL 295

Query: 836  RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 895
            +G PG  G PG PG  G               G  G PG  G  G KG KG++GPPG  G
Sbjct: 296  QGKPGKDGVPGFPGSEGVK-------------GNRGFPGLMGEDGIKGQKGDIGPPGFRG 342

Query: 896  QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP--PGPRGYPGIP 953
              P ++     E KG++G  G  G +G RG  G  G  G  +PG PG   PG RG PG P
Sbjct: 343  --PTEYYDTYQE-KGDEGTPGPPGPRGARGPQGPSGPPG--VPGSPGSSRPGLRGAPGWP 397

Query: 954  GPKG-ESIRGQPGPP--GPQGPPGI-GYEGRQGPPGPPGPPGPPSF----PGPHRQTISV 1005
            G KG +  RG+PG    G  G PG  G  G  G PGPPGPPG   F    PG H      
Sbjct: 398  GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH------ 451

Query: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATR 1033
             G PG  G PG PG  G      L  T+
Sbjct: 452  -GLPGYLGSPGIPGVDGPKGEPGLLCTQ 478



 Score =  168 bits (426), Expect = 3e-41
 Identities = 118/312 (37%), Positives = 134/312 (42%), Gaps = 72/312 (23%)

Query: 766  GSIFSPDGGALGPAQKGAKGEPGFRGPP---------GPYGRPGYKGEIGFPGRPGRPGM 816
            G +    G       KG KGE GF GPP         GP G PG +G  GFPG PG  G 
Sbjct: 30   GCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS 89

Query: 817  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGP------------------PGPPGT----- 853
             G++G  G PG +    G  G+PG PG  GP                  PG PGT     
Sbjct: 90   KGVRGISGLPGFS----GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 854  -------------PVYDSNVFAES-SRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899
                         P  + ++  ++   PG PG PG QG PGP G  G VGPPGPPG F F
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 900  DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPP--------GPRGYPG 951
                     KG  G+R   G KGERG  G        L GPPGPP        GP     
Sbjct: 206  PGAMGPRGPKGHMGER-VIGHKGERGVKG--------LTGPPGPPGTVIVTLTGPDNRTD 256

Query: 952  IPGPKGE-SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPG 1010
            + G KG+    G+PGPPGP G PG  Y   +G PG PG  G P   G        PG  G
Sbjct: 257  LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG----VPGFPGSEG 312

Query: 1011 PPGPPGPPGTMG 1022
              G  G PG MG
Sbjct: 313  VKGNRGFPGLMG 324


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  504 bits (1297), Expect = e-142
 Identities = 337/832 (40%), Positives = 383/832 (46%), Gaps = 134/832 (16%)

Query: 288  GSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGV 347
            G   ED    +   +  +   G    PG    +   G+   PG R ++G  +G+KGE G+
Sbjct: 253  GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD-QGEKGELGL 311

Query: 348  PG------PPGRAGPPGSPCLPGP-------PGLPCPVSPLG-------PAGPALQTVPG 387
            PG        G AGP G P LPG        P +P    P G       P  P LQ  PG
Sbjct: 312  PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 371

Query: 388  ---PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-- 442
               PQGP GPPG  G  G  G PG  G  G PG  G  G  G PG VG  G +G PG   
Sbjct: 372  ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 431

Query: 443  --GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGP------PG 494
              GE+G  G +G PGP GP             G G  G+   LRG  G PGP       G
Sbjct: 432  ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE-PGLRGSPGLPGPLGTKGDRG 490

Query: 495  PPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREG-----PP 549
             PG+PG PG  G  G+  +  PGP+G PG  G  G  G PG PGP GP GR+G      P
Sbjct: 491  APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSP 550

Query: 550  GRTG----------QKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGP 599
            G               G  G  G PG KG KG PG  G  G  G  G  GP G PGPPG 
Sbjct: 551  GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGI 610

Query: 600  PGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 659
             GP G     G D   G             G QG PG+PG  G PG PG PGA G  GA 
Sbjct: 611  AGPQGSQGERGADGEVGQ-----------KGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 659

Query: 660  GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG----------VGQPGLPGPPGPP 709
            G PG  G PG+EG  GPQGP G  G  GE+G  G+DG           G+PGLPGP G  
Sbjct: 660  GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 719

Query: 710  GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF 769
            GP  +      S    PGP G  G  G PG  G  G  G  G  G  GP+G +G PG   
Sbjct: 720  GPPGFKGHTGDS--GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 777

Query: 770  SPD-----GGALGPAQKGAKGE------PGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG 818
            SP      G +  P QKG+KGE      PGF GP GP G PG KG  G  G PG+PG  G
Sbjct: 778  SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837

Query: 819  LKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP 878
             KGE+G+PG       ++G  GPPG  G PG PG P +  +    +   GP GLPG  GP
Sbjct: 838  FKGERGDPG-------IKGDKGPPGGKGQPGDPGIPGHKGH----TGLMGPQGLPGENGP 886

Query: 879  PGPKGAKGEVGPPGPPGQFP-FDFL----------QLE------------AEMKGEKGDR 915
             GP G  G+ G PG  G+ P  + L          QLE            A MK  +G  
Sbjct: 887  VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRP 946

Query: 916  GDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGI 975
            G  G  G+ G PG  G  G   PG PG  G  G  G  GPKGE  RG  G PG    PG+
Sbjct: 947  GPPGPPGKDGLPGRAGPMGE--PGRPGQGGLEGPSGPIGPKGE--RGAKGDPGA---PGV 999

Query: 976  GYEGRQGPPGPPGPPGPPSF--------PGPHRQTISVPGPPGPPGPPGPPG 1019
            G  G  GPPG PG PG P +        PGP  +T    G PG PGPPGPPG
Sbjct: 1000 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGET-GPAGHPGLPGPPGPPG 1050



 Score =  497 bits (1280), Expect = e-140
 Identities = 326/790 (41%), Positives = 378/790 (47%), Gaps = 122/790 (15%)

Query: 325  SVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAG-PALQ 383
            + +T  G  +  G  G++GE G+PG PG  G  G   L G PG        G AG P   
Sbjct: 238  AAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG------EKGEAGLPGAP 291

Query: 384  TVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGT----------PGDVGP 433
              PG +G  G  G  G  G  G  GD GE G+ G  GP G PGT          PG+ GP
Sbjct: 292  GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP 351

Query: 434  KGDKGDPGV----------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEAL 483
            KG+KGDPG+          GE GP GP GPPG  G    H           G  G+  A 
Sbjct: 352  KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHG--------APGAAGNPGA- 402

Query: 484  RGPRGFPGPPGPPG---VPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP 540
             G  G PGP GPPG    PGL G PG+ G       G AG  G PG  GP G PG PG P
Sbjct: 403  PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK--GAAGEEGSPGPVGPRGDPGAPGLP 460

Query: 541  GPPGR--EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGL--AGAPGPAGPPGP 596
            GPPG+  +G PG  G  G  G  G  G +G+ G PG  G+RG+ G+  AG PGP+GPPG 
Sbjct: 461  GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGD 520

Query: 597  PGPPGP------PGPGLPAGFDDMEGSGGPFWSTARSAD-------GPQGPPGLPGLKGD 643
             G PG       PGP  PAG D +     P      + D       GP G PGLPG KGD
Sbjct: 521  KGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 580

Query: 644  PGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGL 702
             GVPG PG +G  G  G  G PGLPG  GIAGPQG +G+RG+ GE G  G  G  G PG 
Sbjct: 581  KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640

Query: 703  PGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEK 762
             GPPG PGP    ++        PG +G PG  G PGP GP G  G  GE G  G  G+ 
Sbjct: 641  MGPPGNPGPPG--ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 698

Query: 763  GEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGE 822
            G PG         L P  +GA+G PGF+G  G  G PG +GE G  G PG+ G+ G  G+
Sbjct: 699  GPPGEPGKAGEPGL-PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 757

Query: 823  KGEPGDASLGFGMRGMPGP---PGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPP 879
             G  G      G RG PG    PG PG PGP GTP    +   E+  PG PG  G +GPP
Sbjct: 758  TGPTGPQGPQ-GPRGPPGKNGSPGSPGEPGPSGTPGQKGSK-GENGSPGLPGFLGPRGPP 815

Query: 880  GP---KGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSS 936
            G    KG  G+ G PG PG+  F   + +  +KG+KG  G  GQ G+ G PG  G  G  
Sbjct: 816  GEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLM 875

Query: 937  LP-------GPPGPPGPRGYPGIPGPKGES------------------------------ 959
             P       GP GPPGP G PG PG +GES                              
Sbjct: 876  GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP 935

Query: 960  ------IRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPG 1013
                   +G+PGPPGP G  G+   GR GP G PG PG     GP        GP GP G
Sbjct: 936  PAYMKSSQGRPGPPGPPGKDGL--PGRAGPMGEPGRPGQGGLEGPS-------GPIGPKG 986

Query: 1014 PPGPPGTMGA 1023
              G  G  GA
Sbjct: 987  ERGAKGDPGA 996



 Score =  471 bits (1211), Expect = e-132
 Identities = 323/799 (40%), Positives = 363/799 (45%), Gaps = 154/799 (19%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV 305
            G  GD G         L  E G   +P    P   T PP A G                 
Sbjct: 353  GEKGDPG---------LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG------AA 397

Query: 306  ASLGAQTLPGSDSVSTWDGSVRTPG-----GRVKEGGLKGQKGEPGVPGPPGRAGPPGSP 360
             + GA    G+   S   GSV  PG     G+  E G KG  GE G PGP G  G PG+P
Sbjct: 398  GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 457

Query: 361  CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG 420
             LPGPPG        G  G      PG +G PG PG  GT G  G PG PG  G  GD G
Sbjct: 458  GLPGPPGK-------GKDGE-----PGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPG 505

Query: 421  PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480
              G  G PG  GP GDKG P  G RG PG  GP GP G       L+          GD+
Sbjct: 506  -IGVAGPPGPSGPPGDKGSP--GSRGLPGFPGPQGPAGRDGLSSLLS---------PGDI 553

Query: 481  EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLP--- 537
              L        PPGPPG+PGLPG  G  GV     PG  G  G  G  GPPG PG P   
Sbjct: 554  NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK--PGREGTEGKKGEAGPPGLPGPPGIA 611

Query: 538  GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597
            GP G  G  G  G  GQKG  G  G PG  G  G PGP GA G +G AG PG  G PG  
Sbjct: 612  GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 671

Query: 598  GPPGPPGP-GLPA-----GFDDMEGSGGPFWSTARSAD----GPQGPPGLPGLKGDPGVP 647
            GPPGP GP GLP      G +  +G  GP     ++ +    GP+G  G PG KG  G  
Sbjct: 672  GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 731

Query: 648  GLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPP 706
            G PG +GE GA G+PG  GLPG++G  GP GP+G +G R   G PGK+G  G PG PGP 
Sbjct: 732  GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR---GPPGKNGSPGSPGEPGPS 788

Query: 707  GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766
            G PG       Q GS     G  G PG  GF GP GP G  G KG  G  G  G+ GEPG
Sbjct: 789  GTPG-------QKGS----KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837

Query: 767  SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEP 826
                          KG +G+PG +G  GP   PG KG+ G PG PG  G  GL G +G P
Sbjct: 838  F-------------KGERGDPGIKGDKGP---PGGKGQPGDPGIPGHKGHTGLMGPQGLP 881

Query: 827  GDASLGFGMRGMPGPPGPPGPPGPPG---------------------------------- 852
            G+        G  GPPGPPG PG PG                                  
Sbjct: 882  GE-------NGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 934

Query: 853  TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEK 912
             P Y   + +   RPGPPG PG  G PG  G  GE G PG  G            ++G  
Sbjct: 935  PPAY---MKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG------------LEGPS 979

Query: 913  GDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGP 972
            G  G  G++G +G+PG  G     L G  GPPG  G PG PG   + + G PGP G  GP
Sbjct: 980  GPIGPKGERGAKGDPGAPGV---GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGP 1036

Query: 973  PGIGYEGRQGPPGPPGPPG 991
                  G  G PGPPGPPG
Sbjct: 1037 -----AGHPGLPGPPGPPG 1050



 Score =  447 bits (1151), Expect = e-125
 Identities = 302/771 (39%), Positives = 356/771 (46%), Gaps = 154/771 (19%)

Query: 349  GPPGRAGPPGSPCLPGPPGLPCPV---------SPLGPAGPALQ-------------TVP 386
            G  G  G   +  LP      C +         + LG  GPA Q             T P
Sbjct: 184  GAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILAAKTAP 243

Query: 387  GPQ---GPPGPPGRDGTPGRDGEPGDPGEDG---KPGDTGPQGFPGTPGDVGPKGDKGDP 440
            G +   G PG  G DG PG+ G  G+ GE G   +PG+ G  G PG PG  G +G+KGD 
Sbjct: 244  GLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 303

Query: 441  GV-------------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPR 487
            G              GE+G  GP GPPG PG        T +        G+    +GP+
Sbjct: 304  GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT-------TSLFTPHPRMPGE----QGPK 352

Query: 488  GFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREG 547
            G  G PG PG PGL G PG  G       GP G PG  G+EG  G PG  G PG PG  G
Sbjct: 353  GEKGDPGLPGEPGLQGRPGELGPQ-----GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG 407

Query: 548  PPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGL 607
             PG +G  GS+G   APG +G+ G  G  G +G +G  G+PGP GP G PG PG PGP  
Sbjct: 408  APGPSGPPGSVG---APGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPP- 463

Query: 608  PAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGL 667
                                    +G  G PGL+G PG+PG  G KG+ GA G+PG PG 
Sbjct: 464  -----------------------GKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGS 500

Query: 668  PGREGIA-----GPQGPKGDRGSRGEKGDPGKDG----VGQPGL-----PG--------- 704
             G  GI      GP GP GD+GS G +G PG  G     G+ GL     PG         
Sbjct: 501  RGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDV 560

Query: 705  ----PPGPPG-PVVYVSEQDGSVLSVPGPEGR---------PGFAGFPGPAGPKGNLGSK 750
                PPGPPG P +   + D  V   PG EG          PG  G PG AGP+G+ G +
Sbjct: 561  CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 620

Query: 751  GERGSPGPKGEKGEPG--SIFSPDGGALGPAQ---KGAKGEPGFRGPPGPYGRPGYKGEI 805
            G  G  G KG++G PG      P G    P      GA G PG +G PG  G PG +G  
Sbjct: 621  GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 680

Query: 806  GFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESS 865
            G PG PG  G  G  G+ G PG+     G  G PG PGP G  GPPG   +  +  A   
Sbjct: 681  GLPGIPGEEGKEGRDGKPGPPGEP----GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 736

Query: 866  R--------PGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGD 917
            R        PG  GLPG  G  GP G +G  GP GPPG+             GE G  G 
Sbjct: 737  RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK------NGSPGSPGEPGPSGT 790

Query: 918  AGQKGERGEPGGGGFFGSSLP-GPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIG 976
             GQKG +GE G  G  G   P GPPG PG +G PG  G  G+   G+PG  G +G PGI 
Sbjct: 791  PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP--GEPGFKGERGDPGI- 847

Query: 977  YEGRQGPPGPPGPPGPPSFPGPHRQT-----ISVPGPPGPPGPPGPPGTMG 1022
             +G +GPPG  G PG P  PG    T       +PG  GP GPPGPPG  G
Sbjct: 848  -KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPG 897



 Score =  329 bits (844), Expect = 9e-90
 Identities = 212/505 (41%), Positives = 241/505 (47%), Gaps = 76/505 (15%)

Query: 314  PGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGP--------------- 356
            PG   +  + G    PG   +EG  G KG+ G PG+PGPPG AGP               
Sbjct: 569  PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 628

Query: 357  ------PGSPCLPGPPGLPCPVSPLGPAG----PALQTVPGPQGPPGPPGRDGTPGRDGE 406
                  PG P   GPPG P P    G AG    P +Q  PG +GPPGP G  G PG  GE
Sbjct: 629  KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGE 688

Query: 407  PGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKL 466
             G  G DGKPG  G  G  G PG  GP+G +G PG   +G  G  G PGP G S     +
Sbjct: 689  EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF--KGHTGDSGAPGPRGES---GAM 743

Query: 467  TFIDMEG-SGFGGDLEAL--RGPRGFPGPPGPPGVPGLPGEPGRFGV-NSSDVPGPAGLP 522
                 EG  G  GD      +GP+G  GPPG  G PG PGEPG  G        G  G P
Sbjct: 744  GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP 803

Query: 523  GVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGES 582
            G+PG  GP G PG PG  G PG+EG PG+ G+ G  GE G PG KG KG PG  G  G+ 
Sbjct: 804  GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDP 863

Query: 583  GL------------AGAPGPAGPPGPPGPPGPPG-PGLPAGFDDME-------GSGGPFW 622
            G+             G PG  GP GPPGPPG PG PGL      ME          G   
Sbjct: 864  GIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQL 923

Query: 623  STARSADGPQGPPG-LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKG 681
             T  +    Q PP  +   +G PG PG PG  G  G  G  G PG PG+ G+ GP GP G
Sbjct: 924  ETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 983

Query: 682  DRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFA--GFPG 739
             +G RG KGDPG  GVG  G  GPPG                 +PG  G PG+A  G PG
Sbjct: 984  PKGERGAKGDPGAPGVGLRGEMGPPG-----------------IPGQPGEPGYAKDGLPG 1026

Query: 740  PAGPKGNLGSKGERGSPGPKGEKGE 764
              GP+G  G  G  G PGP G  G+
Sbjct: 1027 IPGPQGETGPAGHPGLPGPPGPPGQ 1051



 Score =  249 bits (635), Expect = 2e-65
 Identities = 181/534 (33%), Positives = 219/534 (41%), Gaps = 139/534 (26%)

Query: 246  GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTT- 304
            G  GD G      RE    + G A  P LP PP +  P  + G    D    +  +Q   
Sbjct: 576  GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP 635

Query: 305  -----VASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAG-- 355
                 +   G    PG+D ++   G     G   KEG  G +G  G PG+PG  G+ G  
Sbjct: 636  GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 695

Query: 356  ----PPGSPCLPGPPGLPCPVSPLGPAG----------------------PALQTVPG-- 387
                PPG P   G PGLP P    GP G                      P  + +PG  
Sbjct: 696  GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 755

Query: 388  ----------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 437
                      PQGP GPPG++G+PG  GEPG  G  G+ G  G  G PG PG +GP+G  
Sbjct: 756  GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 815

Query: 438  GDPGVGERGPPGPQGPPGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPP 496
            G+PG  E+G PG +G PG PG P F+ ++            GD   ++G +G PG  G P
Sbjct: 816  GEPG--EKGVPGKEGVPGKPGEPGFKGER------------GD-PGIKGDKGPPGGKGQP 860

Query: 497  GVPGLPGEPGRFGV-NSSDVPGPAGLPGVPGREGPPGFPGL------------------- 536
            G PG+PG  G  G+     +PG  G  G PG  G PGFPGL                   
Sbjct: 861  GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELG 920

Query: 537  -------------------------PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKG 571
                                     PGPPGPPG++G PGR G  G  G  G  G +G  G
Sbjct: 921  KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 980

Query: 572  APGPAGARGESGLAGAPGPA-----GPPGPPGPPGPPG---PGLPAGFDDMEGSGGPFWS 623
              GP G RG  G  GAPG       GPPG PG PG PG    GLP               
Sbjct: 981  PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP--------------- 1025

Query: 624  TARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG-IAGP 676
                  G  GP G  G  G PG+PG PG  G+        F  L  R G + GP
Sbjct: 1026 ------GIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1073


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  504 bits (1297), Expect = e-142
 Identities = 377/1049 (35%), Positives = 439/1049 (41%), Gaps = 280/1049 (26%)

Query: 231  VSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSS 290
            V P     E+GD  DGA G  G            + G+  +     PP    P    G  
Sbjct: 1438 VGPPGKKGEKGDSEDGAPGLPG------------QPGSPGEQGPRGPPGAIGPKGDRGFP 1485

Query: 291  TEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPG--GRVKEGGLKGQKGEPGVP 348
                 + E  E+      G++ LPG        G    PG  GR  E G  G+ G+P V 
Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545

Query: 349  GP----------------------------------PGRAGPPGSPCLPGPPGLPCPVSP 374
            GP                                  PG  GP G P   GP GL     P
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605

Query: 375  LGPAGPALQTV----PGPQGPPGPPGRDGTPGRDGE---PGDPGEDGKPGDTGPQGFPGT 427
             G +GP  +      PGP GP GP GRDG  G  G+   PGDPG  GK G+ G +G PG 
Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665

Query: 428  PGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL 480
             G VG KGD+GDPG        G  GP G +G PGPPGP  R        +  +G G   
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR--------LVDTGPGARE 1717

Query: 481  EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS-SDVPGPAGLPGV--------------- 524
            +   G RG  GP GP G PGLPG PG  G+      PGP G PGV               
Sbjct: 1718 KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL 1777

Query: 525  ---------------------------PGREGPPGF---PGLPGPPGPPGREGPPGRTGQ 554
                                       PGR+G PG     GLPGP GPPG  G PG  G+
Sbjct: 1778 DGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK 1837

Query: 555  ---KGSLGEAGAPGHKGSKGAPGPAGA---------RGESGLAGAPGPAGPPGPPGPPGP 602
                G  GE G PG  G KG  G +GA         +GE G  G  GP GPPG PGP GP
Sbjct: 1838 PGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGP 1897

Query: 603  PG---PGLPAG------------------------------------------------- 610
            PG   PG+P G                                                 
Sbjct: 1898 PGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALR 1957

Query: 611  --FDDMEGSGGPFWSTARSADGP------QGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662
               +  + S G F        GP      QGPPG  G  G PG  GL G +G+ G  G P
Sbjct: 1958 EIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPP 2017

Query: 663  ----------------------GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG---- 696
                                  G PGLPGR G  G  G  G+RG RGEKG+ G+ G    
Sbjct: 2018 GLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077

Query: 697  VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP------EGRPGFAGFPGPAGPKGNLGSK 750
             G PG PGPPGPPGP V V E    +    GP      +G PG  G  GP G +G  G K
Sbjct: 2078 PGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIK 2137

Query: 751  GERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGP---YGRPGYKGEIGF 807
            G+RG PGP+G+ G PG     + G  GP  +G  G  G RGPPGP   +G PG  G  G 
Sbjct: 2138 GDRGEPGPRGQDGNPG--LPGERGMAGP--EGKPGLQGPRGPPGPVGGHGDPGPPGAPGL 2193

Query: 808  PGRPGRPGMNGLKGEKGEPGDASLGF----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAE 863
             G  G  G +GLKGE GE G    G     G  G+PGPPGP G  GP G+P     V  E
Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV-GE 2252

Query: 864  SSRP---------------GPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFL------ 902
            + +P               G PG+PG+ G PGP G KGE GP G PGQ            
Sbjct: 2253 TGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312

Query: 903  ----QLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 958
                 L  ++ GE G +GD G  G RGE G  G  G   PG PG  G +G PG  G KG+
Sbjct: 2313 GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGE--PGDPGEDGQKGAPGPKGFKGD 2370

Query: 959  SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP--HRQTISVPGP-------- 1008
               G PG PGP GPPG+  +G  G PG PG PG   FPG    R  +  PGP        
Sbjct: 2371 PGVGVPGSPGPPGPPGV--KGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAG 2428

Query: 1009 -------PGPPGPPGPPGTMG--ASSGVR 1028
                   PGP GPPGPPG++G   +SG++
Sbjct: 2429 PPGREGIPGPLGPPGPPGSVGPPGASGLK 2457



 Score =  495 bits (1274), Expect = e-139
 Identities = 364/988 (36%), Positives = 429/988 (43%), Gaps = 220/988 (22%)

Query: 229  PQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGG 288
            P+  P++C         G  G+ G  +G     LR + G    P LP       P    G
Sbjct: 1244 PEPCPVYC-------PKGQKGEPGE-MG-----LRGQVGPPGDPGLPGRTGAPGPQGPPG 1290

Query: 289  SSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPG 346
            S+T               S G    PG+       GS   PG R   G  G +G KGEPG
Sbjct: 1291 SATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPG 1350

Query: 347  VPGP---------PGRAGPP------------GSPCLPGPPGLPCP-------------- 371
             PG          PGR G P            G P   GPPGLP                
Sbjct: 1351 APGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGP 1410

Query: 372  -------VSPLGPAGPALQTVPGPQGPPGPPGRDGTPG--RDGEPGDPGEDGKPGDTGPQ 422
                   ++P  P  P L   PGPQGP GPPG+ G  G   DG PG PG+ G PG+ GP+
Sbjct: 1411 PGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPR 1470

Query: 423  GFPGTPGDVGPKGDKGDPG-------VGERGPPGP---------------QGPPGPPGPS 460
               G PG +GPKGD+G PG        GERGPPGP               +GP GPPGP+
Sbjct: 1471 ---GPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPT 1527

Query: 461  FRHDKLTFIDMEG--SGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGP 518
             R  +       G  +  G  +   +G +G  GP GP G  G+ GE G  G+     PGP
Sbjct: 1528 GRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGP 1587

Query: 519  AGLP------GVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572
             G P      G+ GR GPPG  G PG  G PGR GPPG  G +G  GE G  G +G  G 
Sbjct: 1588 KGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGD 1647

Query: 573  PGPAGARGESGLAGAP---------------------------GPAGPPGPPGPPGPPGP 605
            PG  G  GE GL GAP                           GP G  G PGPPGPPG 
Sbjct: 1648 PGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR 1707

Query: 606  GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLP---------GLKGDPGVPGLPGAKGEV 656
             +  G    E  G P         GP+G PGLP         G +G PG  G PG +G  
Sbjct: 1708 LVDTGPGARE-KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766

Query: 657  GADGVPGFPGLPGREGI---AGPQGPKGDRGSRGEKGDPGKDGV----GQPGLPGPPGPP 709
            G  G  G PGL GR G+    G  GP G  G+ G+ GDPG+DG+    G+ GLPGP GPP
Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP 1826

Query: 710  GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIF 769
            G +     +DG    + G  G PG  G  G  G KG+ G+ G  G  GPKGE+G PG I 
Sbjct: 1827 G-LPGKPGEDGKP-GLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG-IL 1883

Query: 770  SPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKG----- 824
             P G    P   G  G+ GF G PG  G  G +GE G  G  G PG  GL+GE G     
Sbjct: 1884 GPQGPPGLPGPVGPPGQ-GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNV 1942

Query: 825  ------------------EPGDASLGF---------GMRGMPGPPGPPGPPGPPGTPVYD 857
                              E  D S G          G +G  G  GPPG  GP G P  +
Sbjct: 1943 DRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFP-GE 2001

Query: 858  SNVFAESSRPGPPGLP----GNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKG 913
              +  +   PGP G P    G +GPPGP G  GE G PG PG         EA   GE+G
Sbjct: 2002 RGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERG 2061

Query: 914  DRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPR--------------GYPGIPGPKGE- 958
            +RG+ G++GE+G  G  G  G+  PGPPGPPGP+              G PG+ G KGE 
Sbjct: 2062 ERGEKGERGEQGRDGPPGLPGT--PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEP 2119

Query: 959  ------------------SIRGQPGPPGPQGPPGI----GYEGRQGPPGPPGPPGPPSFP 996
                                RG+PGP G  G PG+    G  G +G PG  GP GPP   
Sbjct: 2120 GSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPV 2179

Query: 997  GPHRQTISVPGPPGPPGPPGPPGTMGAS 1024
            G H      PGPPG PG  GP G  G S
Sbjct: 2180 GGHGD----PGPPGAPGLAGPAGPQGPS 2203



 Score =  479 bits (1233), Expect = e-135
 Identities = 383/1082 (35%), Positives = 459/1082 (42%), Gaps = 248/1082 (22%)

Query: 238  DEEGDDSDGASGDSGSGLGDARELLREETGAA--LKPRLP-------APPPVTTPPLAGG 288
            D   D   G  GDSG+   + R+  + E GA   L P+ P        PP    P + GG
Sbjct: 1849 DPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG 1908

Query: 289  SSTEDSRSEEVE--EQTTVASLGAQTLPGS-------------------DSVSTWD---- 323
            +  +  R E     EQ      G +  PGS                   + V TWD    
Sbjct: 1909 TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSG 1968

Query: 324  ----------------GSVRTPG-----GRVKEGGLKGQKGEPGVPGPPGRA----GPPG 358
                            G    PG     G   E GLKG +G+PG  GPPG A    GPPG
Sbjct: 1969 SFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPG 2028

Query: 359  ------SPCLPGPPGLPCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPG 411
                   P  PG PGLP     +G AG P  +   G +G  G  GRDG PG  G PG PG
Sbjct: 2029 PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPG 2088

Query: 412  -----------------EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGP 453
                             E G PG  G +G PG+ GD GPKGD+G PG+ G+RG PGP+G 
Sbjct: 2089 PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148

Query: 454  PGPPG-PSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNS 512
             G PG P  R          G         L+GPRG PGP G  G PG PG PG  G   
Sbjct: 2149 DGNPGLPGER----------GMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG--P 2196

Query: 513  SDVPGPAGLPGVPGREGPPG--------FPGLPGPPGPPGREGP---PGRTGQKGSLGEA 561
            +   GP+GL G PG  GPPG          GLPGPPGP G  GP   PG  GQ G  G+ 
Sbjct: 2197 AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKP 2256

Query: 562  GAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP---GLPA--------- 609
            GAPG  G+ G  G  G+ G  G  G PGP GP G PGP G PG    GLP          
Sbjct: 2257 GAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316

Query: 610  -------------GFDDMEGSGGPFWSTARSA-------DGPQGPPGLPGLKGDPGV--- 646
                         G   + G  G      R+        DG +G PG  G KGDPGV   
Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376

Query: 647  -----PGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKG---DPGKDGV- 697
                 PG PG KG++G  G+PG PG+ G  G  GP+G  G  G  GE+G    PG++G+ 
Sbjct: 2377 GSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP 2436

Query: 698  ---GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGP------------EGRPGFAG---FPG 739
               G PG PG  GPPG      ++    + +PGP            +GRPG  G     G
Sbjct: 2437 GPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTG 2496

Query: 740  PAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALG-------------------- 777
            P G +G  G KG+ GS G KG+KG+   I  P G  GA G                    
Sbjct: 2497 PPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDN 2556

Query: 778  --PAQKGAKGEPG---------FRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEP 826
              P  KG+KGEPG          RG  GP G+PG  G  G PG PG+ G+ G++GEKG+ 
Sbjct: 2557 GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDV 2616

Query: 827  GDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP------PG 880
            G      G RG+ G  G  G  G  G    +     E+  PG PGL G++G       PG
Sbjct: 2617 GF----MGPRGLKGERGVKGACGLDG----EKGDKGEAGPPGRPGLAGHKGEMGEPGVPG 2668

Query: 881  PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 940
              GA G+ G  GP G   FD         G+ G +GD G+KGERG PG GGF G S  G 
Sbjct: 2669 QSGAPGKEGLIGPKGDRGFD---------GQPGPKGDQGEKGERGTPGIGGFPGPS--GN 2717

Query: 941  PGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHR 1000
             G  GP G PG  GP+G    G  G  G +GPPG    G  G PG PG  G         
Sbjct: 2718 DGSAGPPGPPGSVGPRGPE--GLQGQKGERGPPGERVVGAPGVPGAPGERGE-------- 2767

Query: 1001 QTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR 1060
                  G PGP GP G  G    +        RQ M    H   +G   F+A        
Sbjct: 2768 -----QGRPGPAGPRGEKGEAALTEDDIRGFVRQEM--SQHCACQGQ--FIASGSRPLPS 2818

Query: 1061 VQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILA 1120
                    QL A   L      E   + P   +  + + Y   E+  P A PW +DD  +
Sbjct: 2819 YAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEA-PWDSDDPCS 2877

Query: 1121 SP 1122
             P
Sbjct: 2878 LP 2879



 Score =  373 bits (957), Expect = e-103
 Identities = 246/580 (42%), Positives = 281/580 (48%), Gaps = 63/580 (10%)

Query: 491  GPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPG 550
            GP     V GL     +    +   P P  +    G++G PG  GL G  GPPG  G PG
Sbjct: 1219 GPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPG 1278

Query: 551  RTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAG 610
            RTG  G  G  G+   KG +G PG  G  G  G AG PG  G PG  G PG PGP    G
Sbjct: 1279 RTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPG 1338

Query: 611  FDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGR 670
                 G  G   +  +   G    PGLPG KGDPG  G PG +G +G  G  G PGLPG 
Sbjct: 1339 ERGPRGPKGEPGAPGQVIGGE--GPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG- 1395

Query: 671  EGIAGPQGPKGDRGSRGEKGDPGKDGV--GQPGLPGPPGPPGPVVYV------SEQDGSV 722
                  +G KGDRG RG  G PG+ G+  G+PGLPG PG PGP   V       E+  S 
Sbjct: 1396 ---TAMKGDKGDRGERGPPG-PGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSE 1451

Query: 723  LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKG 782
               PG  G+PG  G  GP GP G +G KG+RG PGP GE GE G    P G A      G
Sbjct: 1452 DGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGE-RGPPGPAGSRGLPG 1510

Query: 783  AKGEPGFRGPPGPYGRPGYKGEIGFPGRPG-----RPGMNGLKGEKGEPGDASL--GFGM 835
              G PG +GP GP G  G +GE G PGRPG      P + G KGEKG+ G A      G+
Sbjct: 1511 VAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGV 1570

Query: 836  RGMPGP-----PGPPGPPGPPGT-----------PVYDSNVFAESSRPGPPGLPGNQGPP 879
            +G  GP     PG PGP G PG            P  DS    E   PG PG PG  GP 
Sbjct: 1571 QGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPR 1630

Query: 880  GPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPG 939
            G  G  GE G  GPPG         E  ++G  G RG  G+KG++G+PG  G  GS  PG
Sbjct: 1631 GRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGS--PG 1688

Query: 940  PPGPPGPRGYPGIPGPKGESI--------------RGQPGPPGPQGPPGI-GYEGRQGPP 984
              GP G RG PG PGP G  +              RGQ GP GP+G PG+ G  G +G  
Sbjct: 1689 SSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIE 1748

Query: 985  GPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGAS 1024
            G  GPPGP   PG       V GP G  G  GPPG  G S
Sbjct: 1749 GFRGPPGPQGDPG-------VRGPAGEKGDRGPPGLDGRS 1781



 Score =  148 bits (374), Expect = 3e-35
 Identities = 103/262 (39%), Positives = 118/262 (45%), Gaps = 47/262 (17%)

Query: 772  DGGALGPAQKG---AKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGD 828
            DG +L  A  G   A  +  F   P P   P Y  +    G+ G PG  GL+G+ G PGD
Sbjct: 1218 DGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPK----GQKGEPGEMGLRGQVGPPGD 1273

Query: 829  ASLGFGMRGMPGPPGPPGPPGPPG--TPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKG 886
                    G+PG  G PGP GPPG  T   +        RPG PG  GN G PG  G KG
Sbjct: 1274 P-------GLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKG 1326

Query: 887  EVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGG-GFFGSSLPGPPGPPG 945
              G PGP               +G+ G+RG  G KGE G PG   G  G  LPG  G PG
Sbjct: 1327 SPGLPGP---------------RGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG 1371

Query: 946  PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISV 1005
            P G PG  GP G+     PGP GP G PG   +G +G  G  GPPGP             
Sbjct: 1372 PSGPPGPRGPLGD-----PGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIA------- 1419

Query: 1006 PGPPGPPGPPGPPGTMGASSGV 1027
               PG PG PG PG+ G    V
Sbjct: 1420 ---PGEPGLPGLPGSPGPQGPV 1438



 Score =  144 bits (362), Expect = 7e-34
 Identities = 134/397 (33%), Positives = 159/397 (40%), Gaps = 59/397 (14%)

Query: 193  RGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDP-QVSPMHCLDEEGDDSDGASGDS 251
            RG   +PG      + G A P   +G+   L     P  V P      +GD  D   G  
Sbjct: 2412 RGEMGQPGPS---GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLP 2468

Query: 252  GSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQ 311
            G         +R E G   +P    P  +T PP + G         E  E+  V S G +
Sbjct: 2469 GPRGERGEPGIRGEDG---RPGQEGPRGLTGPPGSRG---------ERGEKGDVGSAGLK 2516

Query: 312  TLPGSDSVSTWDGSVRTPGGRVKEGG---LKGQKGEPGVPGPPGRAGPPGSPCLPGPPGL 368
               G  +V       R   G + E G   L G KG  G  G PG  G  G P   G  GL
Sbjct: 2517 GDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGL 2576

Query: 369  PCPVSPLGPAG-PALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGE--------------- 412
            P     LGP G P    +PG    PG PG+DG PG  GE GD G                
Sbjct: 2577 PGLRGLLGPQGQPGAAGIPGD---PGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGA 2633

Query: 413  ---DGKPGDTGPQGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPG-------PSF 461
               DG+ GD G  G PG PG  G KG+ G+PGV G+ G PG +G  GP G       P  
Sbjct: 2634 CGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGP 2693

Query: 462  RHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSD----VPG 517
            + D+    +    G GG      GP G  G  GPPG PG  G  G  G+         PG
Sbjct: 2694 KGDQGEKGERGTPGIGG----FPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPG 2749

Query: 518  P--AGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRT 552
                G PGVPG  G  G  G PGP GP G +G    T
Sbjct: 2750 ERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALT 2786


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  490 bits (1262), Expect = e-138
 Identities = 371/982 (37%), Positives = 431/982 (43%), Gaps = 226/982 (23%)

Query: 228  DPQVSPMHCLDEEGDDSDGASGDSG-SGLGD-----ARELLREETGAALKPRLPAPPPVT 281
            DP +SP       G   DGA GD G  GL        R+  +   G A  P     P   
Sbjct: 677  DPGLSP-------GKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPE 729

Query: 282  TPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLK 339
              P A G          V +     S G   LPG   +   DG    PG   K G  G+ 
Sbjct: 730  GSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMP 789

Query: 340  GQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGP------------------- 380
            G  G  G  GPPG  G PG   LPGPPG+P  +  LG  GP                   
Sbjct: 790  GFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEP 849

Query: 381  ------ALQTVPG------------PQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQ 422
                    Q VPG             QG PG PG  G PG  G+ GD G  G PG  GP+
Sbjct: 850  GLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPE 909

Query: 423  GFPGT---PGDVGPKGDKGDPGV-------GERGPPGPQGPPGPPGPSFRHDKLTFIDME 472
            GFPG    PGD GP+G KG PG        G+ GP G +GP GPPG              
Sbjct: 910  GFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAP------------ 957

Query: 473  GSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG-------------------VNSS 513
                   LE   G +GFPG PG  GV G PG+PGR G                   V   
Sbjct: 958  ------GLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEK 1011

Query: 514  DVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAP 573
               G  G PGVPG +G  G PG+PG  G PG  GP G  G +G  G  GA G +G +G  
Sbjct: 1012 GDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPD 1071

Query: 574  GPAGARGESGLAGAPGPAGPPGPPGP---------------PGPPGPGLPAGFDDMEGSG 618
            GPAG +G  GL G PGP G PG PG                PG PGP  P G   + G  
Sbjct: 1072 GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEP 1131

Query: 619  GPFWSTARSADGPQGPPGL------PGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREG 672
            GP     +   GP GPPG       PG  G+PG+PG  G KG++G  G PG  GL G+ G
Sbjct: 1132 GP-----QGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRG 1186

Query: 673  ---IAGPQGPKGDRGSRGEKGDPGKDGV----GQPGLPGPPGPPGPVVYVSEQDGSVLSV 725
               + G  GP G  G +G++GDPG DG     GQ GL G  GPPGP          V  V
Sbjct: 1187 EPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPP--------GVTGV 1238

Query: 726  PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDG--GALGPA---- 779
             GPEG+ G  G  G  G KG  G +G+ G  G  G+ G PG+   P G  G+LGP     
Sbjct: 1239 RGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP-GPKGSRGSLGPTGAPG 1297

Query: 780  QKGAKGEPGFRG------------PPGPYGRPGYKGEIGF----PGRPGRPGMNGLKGEK 823
            + GA+GEPG  G            PPGP G  G +GE G     PG PG  G  G +G++
Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDR 1357

Query: 824  GEPGDASLGF-----GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSR--------PGPP 870
            GEPGD          G+RG PG  G PG PGP G P    +  AE  +        PG  
Sbjct: 1358 GEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRR 1417

Query: 871  GLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKG---ERGEP 927
            G+ G QG PGP+G  G  G  G  G         +A  +GE+GD GD G  G   +RG P
Sbjct: 1418 GVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNP 1477

Query: 928  GGGGFFG----------SSLPGPPGPPGPRGYPG---IPGPKGE-SIRGQPGPPG----- 968
            G  G  G          S LPG  GPPG RG  G   +PG +GE   +GQPG  G     
Sbjct: 1478 GVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFP 1537

Query: 969  -------PQGPPG-IGYEGRQGPPGPPGPPG------------PPSFPGPH-----RQTI 1003
                   P+GPPG IG++G QGP GPPG  G            P   PGP      R   
Sbjct: 1538 GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDW 1597

Query: 1004 SVPGPPGPPGP---PGPPGTMG 1022
             + GP GPPGP   PGPPG  G
Sbjct: 1598 GLQGPRGPPGPRGRPGPPGPPG 1619



 Score =  489 bits (1258), Expect = e-138
 Identities = 346/882 (39%), Positives = 394/882 (44%), Gaps = 144/882 (16%)

Query: 258  ARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSD 317
            AR++   +      PR P P   TTP L    +   S S     + T +      L GS 
Sbjct: 563  ARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP----RPTSSGYSIFHLAGST 618

Query: 318  SVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGP 377
                  G    P G   + GL G  G PG+PG PG  GP G P   G PGLP P    G 
Sbjct: 619  PFPLLMG----PPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQ 674

Query: 378  AG-PALQT------------VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGP--- 421
             G P L              +PG  G PGPPGR G  G  G  G PGE G+PG  G    
Sbjct: 675  KGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGA 734

Query: 422  ------QGFPGTPGDVGPKGDKGDPGV-GERGPPGPQGPPGPPGPSFRHDKLTFIDMEGS 474
                  QG PG  GD GPKG +G  G+ G  G PG  G  G PG   +  K     M   
Sbjct: 735  KGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK-----MGMP 789

Query: 475  GFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFG----VNSSDVPGPAGLPGVPGREGP 530
            GF G +   RGP G  G PG  G+PG PG PG  G    +     PGP G+ G+ G  G 
Sbjct: 790  GFPG-VFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGE 848

Query: 531  PGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGP 590
            PG  G  G  G PG  G PG  G KGS    G PG  G++G PGP G  G+ G  G PGP
Sbjct: 849  PGLKGDKGEQGVPGVSGDPGFQGDKGS---QGLPGFPGARGKPGPLGKVGDKGSIGFPGP 905

Query: 591  AGPPGPPGPPGPPGPGLPAGFDDMEGS---GGPFWSTARSAD-GPQGPPGLPGLKGDPGV 646
             GP G PG  GPPG   P G     G+    GP        D GP GPPG PGL+G PG 
Sbjct: 906  PGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGR 965

Query: 647  PGLPGAKGEVGADGVPGFPGLPGREGIAGPQ---------------GPKGDRGSRGEKGD 691
             G P   G  G DGV G PG PGR G  G Q               G KGDRG  G  G 
Sbjct: 966  KGFP---GRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022

Query: 692  PG-KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFP------------ 738
            PG K  +G PG+PG  G PG               PGP+G PG  G P            
Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGE--------------PGPQGPPGSRGPPGMRGAKGRRGPR 1068

Query: 739  GPAGPKGNLGSKGERGSPGPKGEKGEPGSI-FSPDGGALG-------------PAQKGAK 784
            GP GP G  GS+G +G PGP+G  G PG    + + G LG             P  KG  
Sbjct: 1069 GPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP 1128

Query: 785  GEPGFRGPPGPYGRPGY------KGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGM 838
            GEPG +GP GP G PG        G +G PG PG  GM G  G  G PG+  L  G RG 
Sbjct: 1129 GEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL-IGQRGE 1187

Query: 839  PGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFP 898
            PG  G  GP GP G               G PG  G  G  G +G  GE GPPGPPG   
Sbjct: 1188 PGLEGDSGPMGPDGL----------KGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTG 1237

Query: 899  FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGE 958
                + ++  +GEKG  G  G KG +G+ G  G  G   PGPPG PGP+G  G  GP   
Sbjct: 1238 VRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGD--PGPPGTPGPKGSRGSLGP--- 1292

Query: 959  SIRGQPGPPGPQGPPGI-GYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP 1017
               G PG  G QG PG+ GY+G +G  GP GPPGP    G   +     GPPGPPG  GP
Sbjct: 1293 --TGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGP 1350

Query: 1018 PGTMG-----------ASSGVRLWATRQAMLGQV-HEVPEGW 1047
             G  G              GV+    +    GQ  H  P GW
Sbjct: 1351 VGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGW 1392



 Score =  449 bits (1154), Expect = e-125
 Identities = 315/778 (40%), Positives = 357/778 (45%), Gaps = 149/778 (19%)

Query: 309  GAQTLPGSDSVSTWDGSVRTPGGRVKEG--GLKGQKGEPGVPGPPGRAGPPGSPCLPGPP 366
            G+Q LPG        G +   G +   G  G  G +G PG  GPPG  GP G    PG  
Sbjct: 874  GSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGAR 933

Query: 367  GLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPG---------DPGEDGKPG 417
            GLP P   LGP G       GP GPPG PG +G PGR G PG         +PG+ G+PG
Sbjct: 934  GLPGPRGQLGPEGDE-----GPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPG 988

Query: 418  DTGPQGFPG---------------------TPGDVGPKGDKGDPGV----GERGPPGPQG 452
              G QGF G                      PG  GPKG  G PG+    G  G PGPQG
Sbjct: 989  PVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQG 1048

Query: 453  PPGPPGP-SFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVN 511
            PPG  GP   R  K         G  G+    +G RG  GPPGP G PG PG+ G  G  
Sbjct: 1049 PPGSRGPPGMRGAKGRRGPRGPDGPAGE----QGSRGLKGPPGPQGRPGRPGQQGVAGER 1104

Query: 512  SSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGP---PGRTGQKG---SLGEAGAPG 565
                 G  G PG+PG  GPPG  GLPG PGP G +GP   PG  G KG   ++GE G PG
Sbjct: 1105 GH--LGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG 1162

Query: 566  HKGSKGAPGPAGA---------RGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEG 616
              G KG  GP G          RGE GL G  GP GP G  G  G PGP    G    EG
Sbjct: 1163 EAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEG 1222

Query: 617  SGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPG------LPGR 670
              G         DGP GPPG+ G++G  G  G  G KG  GA G  G+ G      +PG 
Sbjct: 1223 LMGE--------DGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGD 1274

Query: 671  EGIAGPQGPKGDRGSRGEKGDPGKDGV-GQPGLPG---------PPGPPGPVVYVSEQ-- 718
             G  G  GPKG RGS G  G PG+ G  G+PGL G         P GPPGP     EQ  
Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGE 1334

Query: 719  DGSVLSVPGP------------EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766
            DG     PGP             G PG  G+PG  G +G  G  G++G PG  G +G PG
Sbjct: 1335 DGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPG 1394

Query: 767  SIFSP--------DGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNG 818
               S          G A  P ++G +G  G  GP G  GR G +G  G  G PGR G  G
Sbjct: 1395 PKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAG 1454

Query: 819  LKGEKGEPGDAS-LG-FGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPG---PPG-- 871
             +GE+G+ GD   +G  G RG PG  G PG  GPPG          ES  PG   PPG  
Sbjct: 1455 QQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFK-------GESGLPGQLGPPGKR 1507

Query: 872  -------LPGNQGPPGPKGAKGE------------VGPPGPPGQFPFDFLQLEAE---MK 909
                   LPGNQG PG KG  G+             GP GPPG   F  +Q       + 
Sbjct: 1508 GTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLM 1567

Query: 910  GEKGDRGDAGQKGERGEPGGGGFFGS----SLPGPPGPPGPRGYPGIPGPKGESIRGQ 963
            G++G  G  G  G  G PG  G  GS     L GP GPPGPRG PG PGP G  I+ Q
Sbjct: 1568 GKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQ 1625



 Score =  396 bits (1018), Expect = e-110
 Identities = 309/864 (35%), Positives = 361/864 (41%), Gaps = 163/864 (18%)

Query: 277  PPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEG 336
            P  + T P A  +S    +S    ++T  +S     LP    V      V     R  E 
Sbjct: 365  PKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEK 424

Query: 337  GLKGQKGEPGVPGPPGRAGPPGSPCLPGP-PGLPCPVSPLG-----PAGPALQTVPGPQG 390
             ++   G P  P P  R  PP +     P P L    + +      PA     T   P  
Sbjct: 425  PIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPF 484

Query: 391  PPGPPGRDGTPGRDGEPGDPGEDGKP--GDTGPQGFPG--TPGDVGPKGDK---GDPGVG 443
                     TPG       P     P  G + P+  P   TPG   P G K   G     
Sbjct: 485  TALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSA-PTGSKKPIGSEASK 543

Query: 444  ERGPPGPQGPPGP--PGPSFRHDKLTFIDMEGS--------------------------- 474
            + GP      P P  PG + R   L+ +    S                           
Sbjct: 544  KAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPR 603

Query: 475  --GFGGDLEALRGPRGFP---GPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVP---- 525
                G  +  L G   FP   GPPGP G  GLPG PG              LPG+P    
Sbjct: 604  PTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPG--------------LPGLPGIPG 649

Query: 526  -----GREGPPGFPGLPGPPGPPGREGPPG------RTGQKGSL------GEAGAPGHKG 568
                 G  GP G PGLPGPPG  G++G PG        G KG +      G  G PG KG
Sbjct: 650  ARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKG 709

Query: 569  SKGAPGPAGARGES---------GLAGAPGPAGPPGPPGPPGPPGP----GLPAGFDDME 615
             KG PGPAG  GE          G  G PG  G PGP G PGP G     GLP  F    
Sbjct: 710  HKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPG 769

Query: 616  GSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAG 675
              G           G  G PG PG+ G+ G PGL G  GE+G  G PG PGL G  G+ G
Sbjct: 770  SDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLG 829

Query: 676  P---QGPKGDRGSRGEKGDPG-KDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGR 731
            P    GPKG +G  G  G+PG K   G+ G+PG  G PG                G +G 
Sbjct: 830  PIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPG-----------FQGDKGSQGL 878

Query: 732  PGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSP-DGGALG----------PAQ 780
            PGF G  G  GP G +G KG  G PGP G +G PG I  P D G  G          P  
Sbjct: 879  PGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGP 938

Query: 781  KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPG-------DASLGF 833
            +G  G  G  GP GP G PG +G+ G  G PGRPG++G+KGE G+PG          +GF
Sbjct: 939  RGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGF 998

Query: 834  -------------GMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPG 880
                         G RGM GPPG PGP G  G P     +      PGP G PG++GPPG
Sbjct: 999  IGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGM-GTPGEPGPQGPPGSRGPPG 1057

Query: 881  PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 940
             +GAKG  GP GP G              GE+G RG  G  G +G PG  G  G  + G 
Sbjct: 1058 MRGAKGRRGPRGPDGP------------AGEQGSRGLKGPPGPQGRPGRPGQQG--VAGE 1103

Query: 941  PGPPGPRGYPGIPGPKG-ESIRGQPGPPGPQGPPG-IGYEGRQGPPGPPGPPGPPSFPGP 998
             G  G RG+PGIPGP G    +G PG PGPQGP G IG  G  GP GPPG  G P  PG 
Sbjct: 1104 RGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG- 1162

Query: 999  HRQTISVPGPPGPPGPPGPPGTMG 1022
                  + G  GP G PG  G +G
Sbjct: 1163 ---EAGMKGDLGPLGTPGEQGLIG 1183



 Score =  390 bits (1001), Expect = e-108
 Identities = 362/1054 (34%), Positives = 426/1054 (40%), Gaps = 231/1054 (21%)

Query: 150  AASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAG 209
            + +F L    G+W HLAL + G  V L   C + +   L    R   L+PG G F+    
Sbjct: 144  SVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVPVLLPFHRDPALDPG-GSFLFGKM 202

Query: 210  GADPDKFQGVIAELKVRRDPQVSPMHC--LDEEGDDSDG--------ASGDSGSGLGDAR 259
                 +F+G + +  +    QV+  +C  L ++   +D          S DSG       
Sbjct: 203  NPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLFSQDSGRPFTFQS 262

Query: 260  E--LLREETGAALKPRLPAPPPVTTP--PLAGGSSTEDSRSEEVEEQTTVASLG-AQT-- 312
            +  LL  E      P L + P    P   +A  + T+  R+        +A  G AQT  
Sbjct: 263  DLALLGLENLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPL 322

Query: 313  LPGSDSVS---------TWDGSVRTPGGRV-----KEGGLKGQKGEPGVPGPPGRA-GPP 357
            LP   S S         +  GS RTP         K    K  K  P  P  P  +  P 
Sbjct: 323  LPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPI 382

Query: 358  GSP--------------CLP-----GPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRD 398
             SP               LP      P   P P     PA   +Q  PG   PP P  R 
Sbjct: 383  KSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRP 442

Query: 399  --------------------------------------------------GTPGRDGEPG 408
                                                               TPG      
Sbjct: 443  LPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTR 502

Query: 409  DPGEDGKP--GDTGPQGFPG--TPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHD 464
             P     P  G + P+  P   TPG   P G K   G       GP+  P  P P     
Sbjct: 503  PPATMVPPTSGTSTPRTAPAVPTPGS-APTGSKKPIGSEASKKAGPKSSPRKPVPLRPGK 561

Query: 465  KLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-------- 516
                + +       DL     PR     P     P L   P +F ++SS  P        
Sbjct: 562  AARDVPL------SDLTTRPSPR--QPQPSQQTTPALVLAPAQF-LSSSPRPTSSGYSIF 612

Query: 517  ------------GPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAP 564
                        GP G  G  G  GPPG PGLPG PG  G  GPPG  G  G  G  GA 
Sbjct: 613  HLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAK 672

Query: 565  GHKGSKG-APGPA--GARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPF 621
            G KG  G +PG A  GA+G+ GL G  G  GPPG  G  G PG   PAG    +G  GP 
Sbjct: 673  GQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPG---PAGHPGEQGQPGPE 729

Query: 622  WSTARSA----DGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQ 677
             S          G  GP G PG KG  G  GLPG  G  G+DG  G PG+PG+    G  
Sbjct: 730  GSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKR---GKM 786

Query: 678  GPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAG 736
            G  G  G  GE+G PG DG  G+ GLPGPPG PG +              G  G  G  G
Sbjct: 787  GMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLI--------------GDLGVLGPIG 832

Query: 737  FPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGF---RGPP 793
            +PGP G KG +GS GE G  G KGE+G PG   S D G  G   KG++G PGF   RG P
Sbjct: 833  YPGPKGMKGLMGSVGEPGLKGDKGEQGVPG--VSGDPGFQG--DKGSQGLPGFPGARGKP 888

Query: 794  GPYGRPGYKGEIGFPGRP---------GRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGP 844
            GP G+ G KG IGFPG P         G PG NG +G KG+PG   L  G RG  GP G 
Sbjct: 889  GPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLP-GPRGQLGPEGD 947

Query: 845  PGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF-DFLQ 903
             GP GPPG P  +        +PG  G PG  G  G KG  G+ G PGP G+  F  F+ 
Sbjct: 948  EGPMGPPGAPGLE-------GQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIG 1000

Query: 904  LEAE--MKGEKGDR------GDAGQKGERGEPGGGGFFGS-SLPGPPGPPGPRGYPGIPG 954
            L  E  + GEKGDR      G  G KG  G PG  G  G+   PGP GPPG RG PG+ G
Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRG 1060

Query: 955  PKG-------------ESIRGQPGPPGPQGPPG-------------IGYEGRQGPPGPPG 988
             KG             +  RG  GPPGPQG PG             +G  G  G PGP G
Sbjct: 1061 AKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSG 1120

Query: 989  PPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG 1022
            PPG    PG        PGP GP GP GPPG MG
Sbjct: 1121 PPGTKGLPGE-------PGPQGPQGPIGPPGEMG 1147



 Score =  205 bits (522), Expect = 2e-52
 Identities = 165/471 (35%), Positives = 194/471 (41%), Gaps = 93/471 (19%)

Query: 240  EGDDS----DGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTT---PPLAGGSSTE 292
            EGD      DG  GD G    D     + + G   +   P PP VT    P    G   E
Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250

Query: 293  DSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPG 352
              R+     +     LG   +PG        G   TPG        KG +G  G  G PG
Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDP------GPPGTPGP-------KGSRGSLGPTGAPG 1297

Query: 353  RAGPPGSPCLPGPPGLPCPVSPLGPAGPALQT--------VPGPQGPPGPPGRDGTPGRD 404
            R G  G P L G  G    V PLGP GP  +           GP GPPG  G  G  G  
Sbjct: 1298 RMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDR 1357

Query: 405  GEPGDPG---------------EDGKPGDTGPQGFPGTPGDVGPKGDKGDPGV----GER 445
            GEPGDPG               + G+PG  GP+G+PG  G  G +G KG  G     G R
Sbjct: 1358 GEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRR 1417

Query: 446  GPPGPQGPPGPPGPSFRHDKLTFIDMEG----SGFGGDLEALRGPRGFPGPPGP------ 495
            G  G QG PGP G   R         +G     G  G  +  +G  G PGP GP      
Sbjct: 1418 GVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQ-QGEQGDDGDPGPMGPAGKRGN 1476

Query: 496  PGVPGLPGEPGRFGVNS-SDVPGPAGLPG---------VPGREGPPG------------F 533
            PGV GLPG  G  G    S +PG  G PG         +PG +G PG            F
Sbjct: 1477 PGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGF 1536

Query: 534  PGLPG---PPGPPGR---------EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGE 581
            PG+ G   P GPPG           GPPG  G++G +G  G  G  G  G  G  G+RG+
Sbjct: 1537 PGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGD 1596

Query: 582  SGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 632
             GL G  GP GP G PGPPGPPG  +    DD+ G+    W     A  P+
Sbjct: 1597 WGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDL-GAAFQTWMDTSGALRPE 1646


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.142    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,932,408
Number of Sequences: 37866
Number of extensions: 9245670
Number of successful extensions: 389828
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 869
Number of HSP's successfully gapped in prelim test: 2032
Number of HSP's that attempted gapping in prelim test: 34754
Number of HSP's gapped (non-prelim): 48004
length of query: 1336
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1222
effective length of database: 13,930,794
effective search space: 17023430268
effective search space used: 17023430268
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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