BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|166235903 complement component 1, q subcomponent, C chain precursor [Homo sapiens] (245 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|56786155 complement component 1, q subcomponent, C chain prec... 521 e-148 gi|166235903 complement component 1, q subcomponent, C chain pre... 521 e-148 gi|87298828 complement component 1, q subcomponent, B chain prec... 240 9e-64 gi|4757760 adiponectin precursor [Homo sapiens] 159 3e-39 gi|14149712 C1q and tumor necrosis factor related protein 5 prec... 149 2e-36 gi|7705753 complement component 1, q subcomponent, A chain precu... 149 2e-36 gi|65301115 C1q and tumor necrosis factor related protein 9 [Hom... 137 8e-33 gi|56847616 C1q and tumor necrosis factor related protein 9B [Ho... 134 9e-32 gi|13994280 C1q and tumor necrosis factor related protein 7 isof... 133 1e-31 gi|206597454 C1q and tumor necrosis factor related protein 7 iso... 133 1e-31 gi|206597452 C1q and tumor necrosis factor related protein 7 iso... 133 1e-31 gi|94818738 C1q and tumor necrosis factor related protein 2 [Hom... 133 2e-31 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 131 6e-31 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 131 6e-31 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 130 1e-30 gi|122937273 hypothetical protein LOC131149 [Homo sapiens] 127 9e-30 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 124 7e-29 gi|56606142 complement component 1, q subcomponent-like 4 [Homo ... 121 6e-28 gi|58801559 complement component 1, q subcomponent-like 3 [Homo ... 113 1e-25 gi|154937344 complement component 1, q subcomponent-like 2 [Homo... 113 1e-25 gi|5729785 complement component 1, q subcomponent-like 1 [Homo s... 108 4e-24 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 102 2e-22 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 102 2e-22 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 102 2e-22 gi|119508426 alpha 3 type IX collagen [Homo sapiens] 99 4e-21 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 96 3e-20 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 96 3e-20 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 96 3e-20 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 96 3e-20 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 96 3e-20 >gi|56786155 complement component 1, q subcomponent, C chain precursor [Homo sapiens] Length = 245 Score = 521 bits (1341), Expect = e-148 Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 60 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP Sbjct: 1 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 60 Query: 61 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS 120 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS Sbjct: 61 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS 120 Query: 121 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV 180 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV Sbjct: 121 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV 180 Query: 181 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF 240 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF Sbjct: 181 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF 240 Query: 241 LLFPD 245 LLFPD Sbjct: 241 LLFPD 245 >gi|166235903 complement component 1, q subcomponent, C chain precursor [Homo sapiens] Length = 245 Score = 521 bits (1341), Expect = e-148 Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 60 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP Sbjct: 1 MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 60 Query: 61 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS 120 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS Sbjct: 61 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS 120 Query: 121 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV 180 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV Sbjct: 121 VFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCV 180 Query: 181 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF 240 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF Sbjct: 181 LLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGF 240 Query: 241 LLFPD 245 LLFPD Sbjct: 241 LLFPD 245 >gi|87298828 complement component 1, q subcomponent, B chain precursor [Homo sapiens] Length = 253 Score = 240 bits (612), Expect = 9e-64 Identities = 123/246 (50%), Positives = 158/246 (64%), Gaps = 8/246 (3%) Query: 8 LPHLGLKLLLLLLLLPLR--GQANTGCYG---IPGMPGLPGAPGKDGYDGLPGPKGEPGI 62 +P + +L+LLLLL L QA C G IPG+PG+PG PG DG G PG KGE G+ Sbjct: 5 IPWGSIPVLMLLLLLGLIDISQAQLSCTGPPAIPGIPGIPGTPGPDGQPGTPGIKGEKGL 64 Query: 63 PAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVF 122 P + G G G+KG+PG+PG+PGK GP GP G G PG G PG GE G YK + F Sbjct: 65 PGLAGDHGEFGEKGDPGIPGNPGKVGPKGPMGPKGGPGAPGAPGPKGESGDYKATQKIAF 124 Query: 123 TVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCVLL 182 + TR + P + IRF+ V+TN +Y+ +GKFTCKVPGLYYF YHAS NLCV L Sbjct: 125 SATRTINVPLRRDQTIRFDHVITNMNNNYEPRSGKFTCKVPGLYYFTYHASSRGNLCVNL 184 Query: 183 YRS---GVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSG 239 R KVVTFC + T QV +GG++L+L+ GE V+L D ++G++G++S+FSG Sbjct: 185 MRGRERAQKVVTFCDYAYNTFQVTTGGMVLKLEQGENVFLQATDKNSLLGMEGANSIFSG 244 Query: 240 FLLFPD 245 FLLFPD Sbjct: 245 FLLFPD 250 >gi|4757760 adiponectin precursor [Homo sapiens] Length = 244 Score = 159 bits (401), Expect = 3e-39 Identities = 104/233 (44%), Positives = 133/233 (57%), Gaps = 24/233 (10%) Query: 20 LLLPLRGQANTGCY-GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP 78 +LLPL A TG GIPG PG GAPG+DG DG PG KGE G PG+ GPKG GE Sbjct: 27 VLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKG---DPGLIGPKGDIGET 83 Query: 79 GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLI 138 G+P G GP G PG+ G G PG EG Y ++S F+V +T+ PN I Sbjct: 84 GVP------GAEGPRGFPGIQGRKGEPG----EGAY--VYRSAFSVGLETY-VTIPNMPI 130 Query: 139 RFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRSGVKVVTFCGHTS 197 RF + N Q YD STGKF C +PGLYYF YH + + ++ V L++ K + F Sbjct: 131 RFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKD-KAMLFTYDQY 189 Query: 198 KTNQVN--SGGVLLRLQVGEEVWLAVNDYYDMVGI---QGSDSVFSGFLLFPD 245 + N V+ SG VLL L+VG++VWL V + G+ +DS F+GFLL+ D Sbjct: 190 QENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHD 242 >gi|14149712 C1q and tumor necrosis factor related protein 5 precursor [Homo sapiens] Length = 243 Score = 149 bits (377), Expect = 2e-36 Identities = 97/245 (39%), Positives = 130/245 (53%), Gaps = 22/245 (8%) Query: 13 LKLLLLLLLLPLRGQA-----NTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG 67 ++ LL+LLLL L + N PG PGLPG PG G GLPG G G PG Sbjct: 1 MRPLLVLLLLGLAAGSPPLDDNKIPSLCPGHPGLPGTPGHHGSQGLPGRDGRDGRDGAPG 60 Query: 68 IRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTR- 126 G KG+ G PGLPG G GP G G G GP G P +S F+ R Sbjct: 61 APGEKGEGGRPGLPGPRGDPGPRGEAGPAGPTGPAGECSVPP---------RSAFSAKRS 111 Query: 127 QTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRS 185 ++ PP ++ + F+ VL N QG YD TGKFTC+VPG+YYF HA+ + A+L L ++ Sbjct: 112 ESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFTCQVPGVYYFAVHATVYRASLQFDLVKN 171 Query: 186 GVKVVT---FCGHTSKTNQVNSGGVLLRLQVGEEVW--LAVNDYYDMVGIQGSDSVFSGF 240 G + + F G K + SGG ++RL+ ++VW + V DY + +DS FSGF Sbjct: 172 GESIASFFQFFGGWPKPASL-SGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGF 230 Query: 241 LLFPD 245 L++ D Sbjct: 231 LVYSD 235 >gi|7705753 complement component 1, q subcomponent, A chain precursor [Homo sapiens] Length = 245 Score = 149 bits (376), Expect = 2e-36 Identities = 93/239 (38%), Positives = 129/239 (53%), Gaps = 12/239 (5%) Query: 15 LLLLLLLLPLRGQANTG-CYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI-PGIRGPK 72 L+L +L + L C G G G PG+ G GL G +GEPG P I GI+G K Sbjct: 8 LVLCVLAISLASMVTEDLCRAPDGKKGEAGRPGRRGRPGLKGEQGEPGAPGIRTGIQGLK 67 Query: 73 GQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPP 132 G +GEPG G+PGK G GP G G G GI G G G K + + F+ R+ PP Sbjct: 68 GDQGEPGPSGNPGKVGYPGPSGPLGARGIPGIKGTKGSPGNIKDQPRPAFSAIRR--NPP 125 Query: 133 APNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCVLLYRSG----VK 188 +++ F+ V+TN + Y +G+F C VPG YYF + +C+ + S + Sbjct: 126 MGGNVVIFDTVITNQEEPYQNHSGRFVCTVPGYYYFTFQVLSQWEICLSIVSSSRGQVRR 185 Query: 189 VVTFCGHTSK-TNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGS--DSVFSGFLLFP 244 + FC T+K QV SGG++L+LQ G++VW+ + + QGS DSVFSGFL+FP Sbjct: 186 SLGFCDTTNKGLFQVVSGGMVLQLQQGDQVWVEKDPKKGHI-YQGSEADSVFSGFLIFP 243 >gi|65301115 C1q and tumor necrosis factor related protein 9 [Homo sapiens] Length = 333 Score = 137 bits (345), Expect = 8e-33 Identities = 91/246 (36%), Positives = 129/246 (52%), Gaps = 37/246 (15%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH---------- 83 GI G G G+PGK G GL GP GE G+ G +G KG KG+ G G Sbjct: 86 GIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGPTGPEGPRGNIGPL 145 Query: 84 -----PGKNGPMGPPGMPGVPGPMGIPGEP------------GEEGRYKQKF---QSVFT 123 PG GP+G PG G GP G GEP GE+G+ + +S FT Sbjct: 146 GPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGKIGETLVLPKSAFT 205 Query: 124 V-TRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVL 181 V + P+ + I+F+ +L N YDT+ GKFTC + G+YYF YH + + N+ V Sbjct: 206 VGLTVLSKFPSSDMPIKFDKILYNEFNHYDTAAGKFTCHIAGVYYFTYHITVFSRNVQVS 265 Query: 182 LYRSGVKVV-TFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVND---YYDMVGIQGSDSVF 237 L ++GVK++ T + S +Q SGG++L+L++G+EVWL V + + + D+ F Sbjct: 266 LVKNGVKILHTKDAYMSSEDQA-SGGIVLQLKLGDEVWLQVTGGERFNGLFADEDDDTTF 324 Query: 238 SGFLLF 243 +GFLLF Sbjct: 325 TGFLLF 330 Score = 75.9 bits (185), Expect = 3e-14 Identities = 42/85 (49%), Positives = 46/85 (54%), Gaps = 6/85 (7%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPK---GEPGIPAIPGIRGPKGQKGEPGLPGH---PGKN 87 GIPG PG G PG+DG DG G K GEPG P PG G G+KGE G G G Sbjct: 29 GIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGRPGSPGKDGTSGEKGERGADGKVEAKGIK 88 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEG 112 G G G PG GP G+ G GE+G Sbjct: 89 GDQGSRGSPGKHGPKGLAGPMGEKG 113 Score = 63.9 bits (154), Expect = 1e-10 Identities = 32/73 (43%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Query: 40 GLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVP 99 G PG PG G++GLPG G G +G KG GEPG PG PGK+G G G G Sbjct: 26 GHPGIPGNPGHNGLPGRDGR------DGAKGDKGDAGEPGRPGSPGKDGTSGEKGERGAD 79 Query: 100 GPMGIPGEPGEEG 112 G + G G++G Sbjct: 80 GKVEAKGIKGDQG 92 Score = 52.8 bits (125), Expect = 3e-07 Identities = 26/61 (42%), Positives = 31/61 (50%) Query: 57 KGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQ 116 +G PGIP PG G G+ G G G G G G PG PG G G GE G +G+ + Sbjct: 25 QGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGRPGSPGKDGTSGEKGERGADGKVEA 84 Query: 117 K 117 K Sbjct: 85 K 85 >gi|56847616 C1q and tumor necrosis factor related protein 9B [Homo sapiens] Length = 333 Score = 134 bits (336), Expect = 9e-32 Identities = 89/246 (36%), Positives = 128/246 (52%), Gaps = 37/246 (15%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH---------- 83 GI G G G+PGK G GL GP GE G+ G +G KG KG+ G G Sbjct: 86 GIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGPTGPEGPRGNIGPL 145 Query: 84 -----PGKNGPMGPPGMPGVPGPMGIPGEP------------GEEGRYKQKF---QSVFT 123 PG GP+G PG G GP G GEP GE+G+ + +S FT Sbjct: 146 GPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGKIGETLVLPKSAFT 205 Query: 124 V-TRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVL 181 V + P+ + I+F+ +L N YDT+ GKFTC + G+YYF YH + + N+ V Sbjct: 206 VGLTVLSKFPSSDVPIKFDKILYNEFNHYDTAVGKFTCHIAGVYYFTYHITVFSRNVQVS 265 Query: 182 LYRSGVKVV-TFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVND---YYDMVGIQGSDSVF 237 L ++GVK++ T + S +Q SG ++L+L++G+E+WL V + + + D+ F Sbjct: 266 LVKNGVKILHTRDAYVSSEDQA-SGSIVLQLKLGDEMWLQVTGGERFNGLFADEDDDTTF 324 Query: 238 SGFLLF 243 +GFLLF Sbjct: 325 TGFLLF 330 Score = 76.6 bits (187), Expect = 2e-14 Identities = 42/85 (49%), Positives = 46/85 (54%), Gaps = 6/85 (7%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPK---GEPGIPAIPGIRGPKGQKGEPGLPGH---PGKN 87 GIPG PG G PG+DG DG G K GEPG P PG G G+KGE G G G Sbjct: 29 GIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKVEAKGIK 88 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEG 112 G G G PG GP G+ G GE+G Sbjct: 89 GDQGSRGSPGKHGPKGLAGPMGEKG 113 Score = 52.4 bits (124), Expect = 4e-07 Identities = 26/61 (42%), Positives = 31/61 (50%) Query: 57 KGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQ 116 +G PGIP PG G G+ G G G G G G PG PG G G GE G +G+ + Sbjct: 25 QGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKVEA 84 Query: 117 K 117 K Sbjct: 85 K 85 >gi|13994280 C1q and tumor necrosis factor related protein 7 isoform b [Homo sapiens] Length = 289 Score = 133 bits (335), Expect = 1e-31 Identities = 91/241 (37%), Positives = 119/241 (49%), Gaps = 31/241 (12%) Query: 34 GIPGMPGLPGA------------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP 81 G+PG PG PGA PG+DG DG G KGE G + G GP G GE G Sbjct: 38 GLPGPPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQ 97 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK------------FQSVFTVTRQTH 129 G GK GP+GP G G GP+G PG G+ G +S F+V T Sbjct: 98 GETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGITTS 157 Query: 130 QPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRSG-V 187 P +I FN VL N Y+ +TGKF C PG+YYF Y + +L + L +G Sbjct: 158 YPEERLPII-FNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLANKHLAIGLVHNGQY 216 Query: 188 KVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAV--NDYYDMVGIQG-SDSVFSGFLLFP 244 ++ TF +T + V SG ++ LQ +EVWL + D + G +DS+FSGFLL+ Sbjct: 217 RIKTFDANTG-NHDVASGSTVIYLQPEDEVWLEIFFTDQNGLFSDPGWADSLFSGFLLYV 275 Query: 245 D 245 D Sbjct: 276 D 276 >gi|206597454 C1q and tumor necrosis factor related protein 7 isoform b [Homo sapiens] Length = 289 Score = 133 bits (335), Expect = 1e-31 Identities = 91/241 (37%), Positives = 119/241 (49%), Gaps = 31/241 (12%) Query: 34 GIPGMPGLPGA------------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP 81 G+PG PG PGA PG+DG DG G KGE G + G GP G GE G Sbjct: 38 GLPGPPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQ 97 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK------------FQSVFTVTRQTH 129 G GK GP+GP G G GP+G PG G+ G +S F+V T Sbjct: 98 GETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGITTS 157 Query: 130 QPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRSG-V 187 P +I FN VL N Y+ +TGKF C PG+YYF Y + +L + L +G Sbjct: 158 YPEERLPII-FNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLANKHLAIGLVHNGQY 216 Query: 188 KVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAV--NDYYDMVGIQG-SDSVFSGFLLFP 244 ++ TF +T + V SG ++ LQ +EVWL + D + G +DS+FSGFLL+ Sbjct: 217 RIKTFDANTG-NHDVASGSTVIYLQPEDEVWLEIFFTDQNGLFSDPGWADSLFSGFLLYV 275 Query: 245 D 245 D Sbjct: 276 D 276 >gi|206597452 C1q and tumor necrosis factor related protein 7 isoform a [Homo sapiens] Length = 296 Score = 133 bits (335), Expect = 1e-31 Identities = 91/241 (37%), Positives = 119/241 (49%), Gaps = 31/241 (12%) Query: 34 GIPGMPGLPGA------------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP 81 G+PG PG PGA PG+DG DG G KGE G + G GP G GE G Sbjct: 45 GLPGPPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQ 104 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK------------FQSVFTVTRQTH 129 G GK GP+GP G G GP+G PG G+ G +S F+V T Sbjct: 105 GETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGITTS 164 Query: 130 QPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRSG-V 187 P +I FN VL N Y+ +TGKF C PG+YYF Y + +L + L +G Sbjct: 165 YPEERLPII-FNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLANKHLAIGLVHNGQY 223 Query: 188 KVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAV--NDYYDMVGIQG-SDSVFSGFLLFP 244 ++ TF +T + V SG ++ LQ +EVWL + D + G +DS+FSGFLL+ Sbjct: 224 RIKTFDANTG-NHDVASGSTVIYLQPEDEVWLEIFFTDQNGLFSDPGWADSLFSGFLLYV 282 Query: 245 D 245 D Sbjct: 283 D 283 >gi|94818738 C1q and tumor necrosis factor related protein 2 [Homo sapiens] Length = 330 Score = 133 bits (334), Expect = 2e-31 Identities = 87/242 (35%), Positives = 124/242 (51%), Gaps = 30/242 (12%) Query: 31 GCYGIPGMPGLPGA---------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP 81 G G PG PG PG PGKDG DG G +G+ G PG G +G+ G G Sbjct: 85 GPQGPPGPPGAPGPSGMMGRMGFPGKDGQDGHDGDRGDSGEEGPPGRTGNRGKPGPKGKA 144 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQ------------KFQSVFTVTRQTH 129 G G+ GP GP G+ G PG G PG+ G +G+ + +S F+V T Sbjct: 145 GAIGRAGPRGPKGVNGTPGKHGTPGKKGPKGKKGEPGLPGPCSCGSGHTKSAFSVA-VTK 203 Query: 130 QPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRSG-V 187 P I+F+ +L N G Y+ S+GKF C VPG+YYF Y + +L + L +G Sbjct: 204 SYPRERLPIKFDKILMNEGGHYNASSGKFVCGVPGIYYFTYDITLANKHLAIGLVHNGQY 263 Query: 188 KVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGI----QGSDSVFSGFLLF 243 ++ TF +T + V SG +L L+ G+EVWL + Y + G+ +DS+F+GFL++ Sbjct: 264 RIRTFDANTG-NHDVASGSTILALKQGDEVWLQI-FYSEQNGLFYDPYWTDSLFTGFLIY 321 Query: 244 PD 245 D Sbjct: 322 AD 323 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 131 bits (329), Expect = 6e-31 Identities = 88/254 (34%), Positives = 120/254 (47%), Gaps = 42/254 (16%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G PG+PG+ G G G G+PGPKGEPG+P PG G G+ G GL G PGK G + Sbjct: 492 GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPGAL 550 Query: 91 GPPGMPGVPGPMGIPGEPGE----------EGRYKQKF---------------------- 118 GP G PG+PGP G PG PG +G Y Sbjct: 551 GPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGG 610 Query: 119 ----QSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHA-S 173 FT PP + ++FN +L N + +Y+ TG FTC+VPG+YYF YH Sbjct: 611 PAYEMPAFTAELTAPFPPV-GAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHC 669 Query: 174 HTANLCVLLYRSGVKVV-TFCGHTSKTNQVNSGGVLLRLQVGEEVWLAV--NDYYDMVGI 230 N+ V L+++ V+ T+ + SG +L L+ G+ V+L + + Sbjct: 670 KGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAG 729 Query: 231 QGSDSVFSGFLLFP 244 Q S FSG+LL+P Sbjct: 730 QYVHSSFSGYLLYP 743 Score = 95.5 bits (236), Expect = 4e-20 Identities = 46/90 (51%), Positives = 55/90 (61%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPG 82 P+ G G PG+PG+PG G G G PGPKGE GI G GPKG+ G G PG Sbjct: 379 PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPG 438 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG G +GPPGM G+PGP+G GE G++G Sbjct: 439 KPGFLGEVGPPGMRGLPGPIGPKGEAGQKG 468 Score = 93.6 bits (231), Expect = 1e-19 Identities = 49/99 (49%), Positives = 54/99 (54%), Gaps = 13/99 (13%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP---- 81 G G GIPG PG PG G+ G GLPGP G PGI PG GPKG +G G+P Sbjct: 314 GIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALG 372 Query: 82 --------GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG GP G PG+PG+PGPMG PG G G Sbjct: 373 PRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPG 411 Score = 92.8 bits (229), Expect = 2e-19 Identities = 46/100 (46%), Positives = 56/100 (56%), Gaps = 18/100 (18%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGP---------KGEPGIPAIPGIRGPKGQ------- 74 G G PG PG G G G GLPGP KG PG+P +PG+ GPKG+ Sbjct: 432 GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQ 491 Query: 75 --KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 +G PG+PG G +GP+GPPG+PG G G+PG PG G Sbjct: 492 GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG 531 Score = 90.9 bits (224), Expect = 9e-19 Identities = 50/107 (46%), Positives = 56/107 (52%), Gaps = 21/107 (19%) Query: 27 QANTGCYGIPGMPGLPGAP------GKDGYDGLPGP---------KGEPGIPAIPGIRGP 71 Q G G PG+ G PG P G G GLPGP KG PG+P +PG+ GP Sbjct: 422 QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481 Query: 72 KGQKGEP------GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 KG+ G P G PG PG GP GP G PG+PGP G PG PG G Sbjct: 482 KGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG 528 Score = 88.6 bits (218), Expect = 5e-18 Identities = 48/100 (48%), Positives = 55/100 (55%), Gaps = 19/100 (19%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE---------PGLP 81 G G+PG+PG PG PG G G PGPKG+ G+ +PG GP+G+KG PG P Sbjct: 334 GEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEP 392 Query: 82 GHPGKNGPMGPPGMPGVPGP---------MGIPGEPGEEG 112 G PG GPMGPPG G PGP G PG GE G Sbjct: 393 GLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPG 432 Score = 88.2 bits (217), Expect = 6e-18 Identities = 51/125 (40%), Positives = 66/125 (52%), Gaps = 15/125 (12%) Query: 3 VGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPG--------APGKDGYDG-- 52 +G ++P G ++ L L + G G PG PGLPG PG GY G Sbjct: 99 MGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVG 158 Query: 53 ---LPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGV--PGPMGIPGE 107 +PG G+PG +PG +G GQKGE G G PG GP GP G+PG+ PG G+PG+ Sbjct: 159 KPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQ 218 Query: 108 PGEEG 112 PG +G Sbjct: 219 PGPKG 223 Score = 88.2 bits (217), Expect = 6e-18 Identities = 46/93 (49%), Positives = 57/93 (61%), Gaps = 10/93 (10%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI--PAIPGIRGPKGQKGEPGLP 81 LRG +G+PG PG+ G PG G PGP G PG+ P + G GP+G G+PG P Sbjct: 236 LRGPKGDKGFGMPGAPGVKGPPGMHGP---PGPVGLPGVGKPGVTGFPGPQGPLGKPGAP 292 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIP--GEPGEEG 112 G PG P GP G+PGV GP GIP G+PG++G Sbjct: 293 GEPG---PQGPIGVPGVQGPPGIPGIGKPGQDG 322 Score = 84.0 bits (206), Expect = 1e-16 Identities = 41/85 (48%), Positives = 50/85 (58%), Gaps = 3/85 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGPKGQKGEPGLPGHPGKN 87 G G G PG G PG G+ G PG GE PG+ +PG GPKG+ G+ G+PG PG Sbjct: 417 GIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP 476 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEG 112 G +GP G PG+PG G+ G PG G Sbjct: 477 GLLGPKGEPGIPGDQGLQGPPGIPG 501 Score = 81.6 bits (200), Expect = 6e-16 Identities = 48/116 (41%), Positives = 56/116 (48%), Gaps = 28/116 (24%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDG------------LPGPKG-----------EPG 61 +G G G+PGMPG PGA G G G +PGP+G +PG Sbjct: 152 QGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPG 211 Query: 62 IPAIPGIRGPKGQKGEPGLPGHPGKNGP-----MGPPGMPGVPGPMGIPGEPGEEG 112 P +PG GPKG +G GLPG G GP G PG PGV GP G+ G PG G Sbjct: 212 GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG 267 Score = 81.6 bits (200), Expect = 6e-16 Identities = 45/105 (42%), Positives = 54/105 (51%), Gaps = 16/105 (15%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGY---DGLPGPKGEP--GIPAIPGIRGPKGQK--- 75 L G G G+PG PG G G G GL GPKG+ G+P PG++GP G Sbjct: 204 LPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPP 263 Query: 76 --------GEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G+PG+ G PG GP+G PG PG PGP G G PG +G Sbjct: 264 GPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQG 308 Score = 81.6 bits (200), Expect = 6e-16 Identities = 45/100 (45%), Positives = 54/100 (54%), Gaps = 21/100 (21%) Query: 34 GIPGMPGLPGAPGKDGY------------DGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP 81 G+PG+PG G PG G+ G PGPKGEPG+ PG G G+ G PG+ Sbjct: 393 GLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMR 452 Query: 82 GHPGKNGPMGP------PGMPGVP---GPMGIPGEPGEEG 112 G PG GP G PG+PGVP GP G PG PG++G Sbjct: 453 GLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQG 492 Score = 80.1 bits (196), Expect = 2e-15 Identities = 48/111 (43%), Positives = 55/111 (49%), Gaps = 18/111 (16%) Query: 24 LRGQANTGCYGIPG------MPGLPGAPGKDGYDGLPGPKGEPGIPAI-----------P 66 L G G G PG PG PG PG G G+PG +G PGIP I P Sbjct: 268 LPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQP 327 Query: 67 GIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 G G KG++G PGLPG PG G +G PG PG G G+ G PG G +K Sbjct: 328 GFPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEK 377 Score = 77.8 bits (190), Expect = 8e-15 Identities = 47/98 (47%), Positives = 52/98 (53%), Gaps = 17/98 (17%) Query: 26 GQANTGCYGIPGMPGLPGA--------PGKDGYDGLPG---PKGEPGIPAIPGIRGPKGQ 74 G+ G G+PG PGLPG G G G+PG P+GE G PGI GP Sbjct: 332 GKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGP--- 388 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GEPGLPG P GPMGPPG G PGP G G G +G Sbjct: 389 PGEPGLPGIP---GPMGPPGAIGFPGPKGEGGIVGPQG 423 Score = 73.6 bits (179), Expect = 2e-13 Identities = 37/68 (54%), Positives = 44/68 (64%), Gaps = 2/68 (2%) Query: 46 GKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIP 105 G+ G G PGP+G PG P +PG G G KG+PG G+PG P G PGMPG PG MG+P Sbjct: 118 GEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQGYPGVGKP-GMPGMPGKPGAMGMP 175 Query: 106 GEPGEEGR 113 G GE G+ Sbjct: 176 GAKGEIGQ 183 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 131 bits (329), Expect = 6e-31 Identities = 88/254 (34%), Positives = 120/254 (47%), Gaps = 42/254 (16%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G PG+PG+ G G G G+PGPKGEPG+P PG G G+ G GL G PGK G + Sbjct: 492 GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI-GKPGVAGLHGPPGKPGAL 550 Query: 91 GPPGMPGVPGPMGIPGEPGE----------EGRYKQKF---------------------- 118 GP G PG+PGP G PG PG +G Y Sbjct: 551 GPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGG 610 Query: 119 ----QSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHA-S 173 FT PP + ++FN +L N + +Y+ TG FTC+VPG+YYF YH Sbjct: 611 PAYEMPAFTAELTAPFPPV-GAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHC 669 Query: 174 HTANLCVLLYRSGVKVV-TFCGHTSKTNQVNSGGVLLRLQVGEEVWLAV--NDYYDMVGI 230 N+ V L+++ V+ T+ + SG +L L+ G+ V+L + + Sbjct: 670 KGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAG 729 Query: 231 QGSDSVFSGFLLFP 244 Q S FSG+LL+P Sbjct: 730 QYVHSSFSGYLLYP 743 Score = 95.5 bits (236), Expect = 4e-20 Identities = 46/90 (51%), Positives = 55/90 (61%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPG 82 P+ G G PG+PG+PG G G G PGPKGE GI G GPKG+ G G PG Sbjct: 379 PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPG 438 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG G +GPPGM G+PGP+G GE G++G Sbjct: 439 KPGFLGEVGPPGMRGLPGPIGPKGEAGQKG 468 Score = 93.6 bits (231), Expect = 1e-19 Identities = 49/99 (49%), Positives = 54/99 (54%), Gaps = 13/99 (13%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP---- 81 G G GIPG PG PG G+ G GLPGP G PGI PG GPKG +G G+P Sbjct: 314 GIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALG 372 Query: 82 --------GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG GP G PG+PG+PGPMG PG G G Sbjct: 373 PRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPG 411 Score = 92.8 bits (229), Expect = 2e-19 Identities = 46/100 (46%), Positives = 56/100 (56%), Gaps = 18/100 (18%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGP---------KGEPGIPAIPGIRGPKGQ------- 74 G G PG PG G G G GLPGP KG PG+P +PG+ GPKG+ Sbjct: 432 GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQ 491 Query: 75 --KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 +G PG+PG G +GP+GPPG+PG G G+PG PG G Sbjct: 492 GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG 531 Score = 90.9 bits (224), Expect = 9e-19 Identities = 50/107 (46%), Positives = 56/107 (52%), Gaps = 21/107 (19%) Query: 27 QANTGCYGIPGMPGLPGAP------GKDGYDGLPGP---------KGEPGIPAIPGIRGP 71 Q G G PG+ G PG P G G GLPGP KG PG+P +PG+ GP Sbjct: 422 QGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP 481 Query: 72 KGQKGEP------GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 KG+ G P G PG PG GP GP G PG+PGP G PG PG G Sbjct: 482 KGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPG 528 Score = 88.6 bits (218), Expect = 5e-18 Identities = 48/100 (48%), Positives = 55/100 (55%), Gaps = 19/100 (19%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE---------PGLP 81 G G+PG+PG PG PG G G PGPKG+ G+ +PG GP+G+KG PG P Sbjct: 334 GEQGLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEP 392 Query: 82 GHPGKNGPMGPPGMPGVPGP---------MGIPGEPGEEG 112 G PG GPMGPPG G PGP G PG GE G Sbjct: 393 GLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPG 432 Score = 88.2 bits (217), Expect = 6e-18 Identities = 51/125 (40%), Positives = 66/125 (52%), Gaps = 15/125 (12%) Query: 3 VGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPG--------APGKDGYDG-- 52 +G ++P G ++ L L + G G PG PGLPG PG GY G Sbjct: 99 MGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVG 158 Query: 53 ---LPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGV--PGPMGIPGE 107 +PG G+PG +PG +G GQKGE G G PG GP GP G+PG+ PG G+PG+ Sbjct: 159 KPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQ 218 Query: 108 PGEEG 112 PG +G Sbjct: 219 PGPKG 223 Score = 88.2 bits (217), Expect = 6e-18 Identities = 46/93 (49%), Positives = 57/93 (61%), Gaps = 10/93 (10%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI--PAIPGIRGPKGQKGEPGLP 81 LRG +G+PG PG+ G PG G PGP G PG+ P + G GP+G G+PG P Sbjct: 236 LRGPKGDKGFGMPGAPGVKGPPGMHGP---PGPVGLPGVGKPGVTGFPGPQGPLGKPGAP 292 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIP--GEPGEEG 112 G PG P GP G+PGV GP GIP G+PG++G Sbjct: 293 GEPG---PQGPIGVPGVQGPPGIPGIGKPGQDG 322 Score = 84.0 bits (206), Expect = 1e-16 Identities = 41/85 (48%), Positives = 50/85 (58%), Gaps = 3/85 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGPKGQKGEPGLPGHPGKN 87 G G G PG G PG G+ G PG GE PG+ +PG GPKG+ G+ G+PG PG Sbjct: 417 GIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP 476 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEG 112 G +GP G PG+PG G+ G PG G Sbjct: 477 GLLGPKGEPGIPGDQGLQGPPGIPG 501 Score = 81.6 bits (200), Expect = 6e-16 Identities = 48/116 (41%), Positives = 56/116 (48%), Gaps = 28/116 (24%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDG------------LPGPKG-----------EPG 61 +G G G+PGMPG PGA G G G +PGP+G +PG Sbjct: 152 QGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPG 211 Query: 62 IPAIPGIRGPKGQKGEPGLPGHPGKNGP-----MGPPGMPGVPGPMGIPGEPGEEG 112 P +PG GPKG +G GLPG G GP G PG PGV GP G+ G PG G Sbjct: 212 GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVG 267 Score = 81.6 bits (200), Expect = 6e-16 Identities = 45/105 (42%), Positives = 54/105 (51%), Gaps = 16/105 (15%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGY---DGLPGPKGEP--GIPAIPGIRGPKGQK--- 75 L G G G+PG PG G G G GL GPKG+ G+P PG++GP G Sbjct: 204 LPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPP 263 Query: 76 --------GEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G+PG+ G PG GP+G PG PG PGP G G PG +G Sbjct: 264 GPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQG 308 Score = 81.6 bits (200), Expect = 6e-16 Identities = 45/100 (45%), Positives = 54/100 (54%), Gaps = 21/100 (21%) Query: 34 GIPGMPGLPGAPGKDGY------------DGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP 81 G+PG+PG G PG G+ G PGPKGEPG+ PG G G+ G PG+ Sbjct: 393 GLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMR 452 Query: 82 GHPGKNGPMGP------PGMPGVP---GPMGIPGEPGEEG 112 G PG GP G PG+PGVP GP G PG PG++G Sbjct: 453 GLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQG 492 Score = 80.1 bits (196), Expect = 2e-15 Identities = 48/111 (43%), Positives = 55/111 (49%), Gaps = 18/111 (16%) Query: 24 LRGQANTGCYGIPG------MPGLPGAPGKDGYDGLPGPKGEPGIPAI-----------P 66 L G G G PG PG PG PG G G+PG +G PGIP I P Sbjct: 268 LPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQP 327 Query: 67 GIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 G G KG++G PGLPG PG G +G PG PG G G+ G PG G +K Sbjct: 328 GFPGGKGEQGLPGLPGPPGLPG-IGKPGFPGPKGDRGMGGVPGALGPRGEK 377 Score = 77.8 bits (190), Expect = 8e-15 Identities = 47/98 (47%), Positives = 52/98 (53%), Gaps = 17/98 (17%) Query: 26 GQANTGCYGIPGMPGLPGA--------PGKDGYDGLPG---PKGEPGIPAIPGIRGPKGQ 74 G+ G G+PG PGLPG G G G+PG P+GE G PGI GP Sbjct: 332 GKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGP--- 388 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GEPGLPG P GPMGPPG G PGP G G G +G Sbjct: 389 PGEPGLPGIP---GPMGPPGAIGFPGPKGEGGIVGPQG 423 Score = 73.6 bits (179), Expect = 2e-13 Identities = 37/68 (54%), Positives = 44/68 (64%), Gaps = 2/68 (2%) Query: 46 GKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIP 105 G+ G G PGP+G PG P +PG G G KG+PG G+PG P G PGMPG PG MG+P Sbjct: 118 GEQGPRGEPGPRGPPGPPGLPG-HGIPGIKGKPGPQGYPGVGKP-GMPGMPGKPGAMGMP 175 Query: 106 GEPGEEGR 113 G GE G+ Sbjct: 176 GAKGEIGQ 183 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 130 bits (327), Expect = 1e-30 Identities = 102/303 (33%), Positives = 134/303 (44%), Gaps = 87/303 (28%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI------------------------ 62 + + G G PG PG PG G G GLPGPKG+PG+ Sbjct: 379 RGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGE 438 Query: 63 ------PAIPGIRGP---------KGQKGEPGLPGHPGK--------NGPMGPP------ 93 P IPG RGP G KG+PG PG PG NGP GPP Sbjct: 439 AGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPR 498 Query: 94 ---GMPGVPGPMGIPGEPGE----EGRYKQKFQ--------------------SVFTVTR 126 G PG+PGP G PG PG+ EG K + S FTV Sbjct: 499 GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVI- 557 Query: 127 QTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRS 185 + PA + I F+ +L N Q YD TG FTC++PG+YYF YH ++ V LY++ Sbjct: 558 LSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKN 617 Query: 186 GVKVV-TFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSD---SVFSGFL 241 G V+ T+ +T SG ++ L ++VWL + + + G+ S+ S FSGFL Sbjct: 618 GTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPN-AESNGLYSSEYVHSSFSGFL 676 Query: 242 LFP 244 + P Sbjct: 677 VAP 679 Score = 90.1 bits (222), Expect = 2e-18 Identities = 45/87 (51%), Positives = 53/87 (60%), Gaps = 5/87 (5%) Query: 31 GCYGIPGMPGLPGAPGKDGYD--GLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNG 88 G G+PG PG+ G PG G+ GLPG KGE G +PG G KG++G GLPG PG G Sbjct: 279 GTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTG 338 Query: 89 P---MGPPGMPGVPGPMGIPGEPGEEG 112 P MGP G G+PG G+PG GE G Sbjct: 339 PPGNMGPQGPKGIPGSHGLPGPKGETG 365 Score = 89.0 bits (219), Expect = 3e-18 Identities = 49/100 (49%), Positives = 58/100 (58%), Gaps = 14/100 (14%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE--------PGIPAIPGIRGPKGQ 74 P + + G G PG PG G+PG G GLPGP G PG+P PG RGP G Sbjct: 67 PAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGP 125 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGI--PGEPGEEG 112 KG+ G G PG P GPPG PG+PGP GI PG+PG++G Sbjct: 126 KGDVGPAGLPG---PRGPPGPPGIPGPAGISVPGKPGQQG 162 Score = 88.6 bits (218), Expect = 5e-18 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 2/90 (2%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI--PGIRGPKGQKGEPGLPG 82 RG G G G PG PG PG G G PG G PG P PG+ G KG++G GLPG Sbjct: 258 RGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPG 317 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG G GP G+PG PG G PG G +G Sbjct: 318 GPGAKGEQGPAGLPGKPGLTGPPGNMGPQG 347 Score = 86.3 bits (212), Expect = 2e-17 Identities = 42/82 (51%), Positives = 48/82 (58%), Gaps = 5/82 (6%) Query: 37 GMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPG-----LPGHPGKNGPMG 91 G PG+PG PGK G G GPKG+ G +PG RGP G G PG +PG PG+ GP G Sbjct: 106 GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTG 165 Query: 92 PPGMPGVPGPMGIPGEPGEEGR 113 PG G PG G PG PG G+ Sbjct: 166 APGPRGFPGEKGAPGVPGMNGQ 187 Score = 85.1 bits (209), Expect = 5e-17 Identities = 53/123 (43%), Positives = 62/123 (50%), Gaps = 27/123 (21%) Query: 2 DVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGL--PGAPGKDGYDGLPGPKGE 59 DVGP+ LP + G GIPG G+ PG PG+ G G PGP+G Sbjct: 128 DVGPAGLPG---------------PRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGF 172 Query: 60 PGIPAIPGIRGPKGQKGE-----PGLPGH---PGKNGPMGPPGMPGV--PGPMGIPGEPG 109 PG PG+ G GQKGE PG PG PG GP GP G PGV G G+PG+PG Sbjct: 173 PGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPG 232 Query: 110 EEG 112 +G Sbjct: 233 IKG 235 Score = 84.7 bits (208), Expect = 7e-17 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 12/94 (12%) Query: 31 GCYGIPGMPGLPGAPGK---------DGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGL- 80 G G+PG PGL G PG G GLPGPKGE G G G KG++G PG Sbjct: 326 GPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 385 Query: 81 --PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+PGK G GP G PG+PGP G PG G G Sbjct: 386 GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPG 419 Score = 83.6 bits (205), Expect = 1e-16 Identities = 44/98 (44%), Positives = 52/98 (53%), Gaps = 11/98 (11%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI--PAIPGIRGPKGQKGEPGLPGH 83 G G G PG PG+PG G G G+ GP G PG P +PG++G +G G PG PG Sbjct: 262 GIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGA 321 Query: 84 PGKNGPMGPPGMPGV---P------GPMGIPGEPGEEG 112 G+ GP G PG PG+ P GP GIPG G G Sbjct: 322 KGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPG 359 Score = 82.4 bits (202), Expect = 3e-16 Identities = 49/114 (42%), Positives = 53/114 (46%), Gaps = 15/114 (13%) Query: 31 GCYGIPGMPGLPGA------------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP 78 G GIPG GLPG PG G G PG G+PG P PG+ GP KG P Sbjct: 347 GPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGP---KGNP 403 Query: 79 GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPP 132 GLPG G G GPPG+PG GP G G PG G + TR PP Sbjct: 404 GLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPP 457 Score = 82.0 bits (201), Expect = 4e-16 Identities = 46/108 (42%), Positives = 54/108 (50%), Gaps = 19/108 (17%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP-----KGEPGIPAIPGIRGPKGQKGE- 77 + GQ YG PG PG G PG G G GP +GE G+P PGI+G +G GE Sbjct: 184 MNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEM 243 Query: 78 -----PGLPGHPGKNGP--------MGPPGMPGVPGPMGIPGEPGEEG 112 PG G PG+ GP G PG PG+PG G+PG PG G Sbjct: 244 GPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAG 291 Score = 81.3 bits (199), Expect = 7e-16 Identities = 40/79 (50%), Positives = 45/79 (56%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G G+PG PGA G+ G GLPG G G P G +GPKG G GLPG G+ GP GP Sbjct: 311 GPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPA 370 Query: 94 GMPGVPGPMGIPGEPGEEG 112 G PG G G PG G+ G Sbjct: 371 GYPGAKGERGSPGSDGKPG 389 Score = 77.8 bits (190), Expect = 8e-15 Identities = 41/91 (45%), Positives = 47/91 (51%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G GLPG PG G G GP+G GIP G+ GPKG+ G G G+PG G Sbjct: 320 GAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGER 379 Query: 91 GP---------PGMPGVPGPMGIPGEPGEEG 112 G PG PG+ GP G PG PG +G Sbjct: 380 GSPGSDGKPGYPGKPGLDGPKGNPGLPGPKG 410 Score = 73.9 bits (180), Expect = 1e-13 Identities = 47/121 (38%), Positives = 55/121 (45%), Gaps = 34/121 (28%) Query: 26 GQANTGCYGIPGMPGLPGA---PGKDGYDGLPGPKGEPG--------------IPAIPGI 68 G G G+PG PG+ G PG+ G G PGP+G PG P PGI Sbjct: 218 GVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGI 277 Query: 69 RGPKGQKGEPGL-----------PGHPGKNGPMGPPGMPGVP------GPMGIPGEPGEE 111 G KG G PG+ PG PG G GP G+PG P GP G+PG+PG Sbjct: 278 PGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLT 337 Query: 112 G 112 G Sbjct: 338 G 338 Score = 65.5 bits (158), Expect = 4e-11 Identities = 33/71 (46%), Positives = 38/71 (53%), Gaps = 10/71 (14%) Query: 57 KGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP--MGPPGMPGVPGPM--------GIPG 106 +GE G P PG GP+G G G PG PG P G PG+PG PGP G+PG Sbjct: 56 RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPG 115 Query: 107 EPGEEGRYKQK 117 +PGE G Y K Sbjct: 116 KPGERGPYGPK 126 >gi|122937273 hypothetical protein LOC131149 [Homo sapiens] Length = 477 Score = 127 bits (319), Expect = 9e-30 Identities = 77/218 (35%), Positives = 109/218 (50%), Gaps = 4/218 (1%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G GM G G+ G G +G G G PG PGI+G KG+ G PGL G G G + Sbjct: 254 GQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDI 313 Query: 91 GPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGD 150 G G+ G G G G G +G + +S F+ PP PN I+F +L N QG+ Sbjct: 314 GNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPP-PNIPIKFEKILYNDQGN 372 Query: 151 YDTSTGKFTCKVPGLYYFVYHASHTANLCVLLYRSGVKVVTFCGHTSKTNQVNSGG--VL 208 Y TGKF C +PG Y F YH + + + K T +++ V+ Sbjct: 373 YSPVTGKFNCSIPGTYVFSYHITVRGRPARISLVAQNKKQFKSRETLYGQEIDQASLLVI 432 Query: 209 LRLQVGEEVWLAVNDYYDMVGIQG-SDSVFSGFLLFPD 245 L+L G++VWL V+ ++ V + DS+F+GFLL+P+ Sbjct: 433 LKLSAGDQVWLEVSKDWNGVYVSAEDDSIFTGFLLYPE 470 Score = 74.3 bits (181), Expect = 9e-14 Identities = 37/81 (45%), Positives = 45/81 (55%), Gaps = 3/81 (3%) Query: 32 CYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMG 91 C +PG G PG G+ G G G G PG P + G +GP+G KGE GL G+ G G Sbjct: 105 CSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGL---KGERGDQG 161 Query: 92 PPGMPGVPGPMGIPGEPGEEG 112 PG PG PG G PG G++G Sbjct: 162 VPGYPGKPGAQGEPGPKGDKG 182 Score = 71.2 bits (173), Expect = 7e-13 Identities = 43/118 (36%), Positives = 52/118 (44%), Gaps = 27/118 (22%) Query: 27 QANTGCYGIPGMP------------------------GLPGAPGKDGYDGLPGPKGEPGI 62 + G GIPG P G+PG PGK G G PGPKG+ G Sbjct: 124 KGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGN 183 Query: 63 PAIPGIRGPKGQKGEP---GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 + G++G KG KG+ G G G MG PG+ G PG G GE GE+G K Sbjct: 184 IGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDK 241 Score = 70.5 bits (171), Expect = 1e-12 Identities = 38/85 (44%), Positives = 47/85 (55%), Gaps = 3/85 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE---PGLPGHPGKN 87 G G PG G PG G+ G G+PGP G G G +G KG KGE G+PG+PGK Sbjct: 110 GQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKP 169 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEG 112 G G PG G G +G+ G G++G Sbjct: 170 GAQGEPGPKGDKGNIGLGGVKGQKG 194 Score = 69.3 bits (168), Expect = 3e-12 Identities = 41/105 (39%), Positives = 48/105 (45%), Gaps = 18/105 (17%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE------------- 77 G G G G+PG PGK G G PGPKG+ G + G++G KG KG+ Sbjct: 152 GLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQ 211 Query: 78 -----PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 PGL G PG G G G G G G G+ GE G QK Sbjct: 212 GAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQK 256 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 124 bits (311), Expect = 7e-29 Identities = 97/285 (34%), Positives = 124/285 (43%), Gaps = 67/285 (23%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQ-------- 74 P + G G PG PG+ GA G+ G GLPG G G IPG++GP G Sbjct: 422 PTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG 481 Query: 75 -KGEPGLPGHPGKN--------GPMGPPGMP------GVPGPMGIPGEPGEEGRY----- 114 KGEPGLPG PG+ GP GPPG+P G PGP G PG PG G + Sbjct: 482 LKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGI 541 Query: 115 -------------------KQKF---------QSVFTVTRQTHQPPAPNSLIRFNAVLTN 146 K +F FT T PA ++F+ L N Sbjct: 542 AGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAV-LTSPFPASGMPVKFDRTLYN 600 Query: 147 PQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRSGVKVV-TFCGHTSKTNQVNS 204 Y+ +TG FTC V G+YYF YH N+ V LY++ V T+ + S Sbjct: 601 GHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQAS 660 Query: 205 GGVLLRLQVGEEVWLAV-----NDYYDMVGIQGSDSVFSGFLLFP 244 GG +L+L+ ++VW+ + N Y I S FSGFLL P Sbjct: 661 GGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSS---FSGFLLCP 702 Score = 94.0 bits (232), Expect = 1e-19 Identities = 44/83 (53%), Positives = 54/83 (65%), Gaps = 6/83 (7%) Query: 35 IPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPG 94 IPG PG G PG G+ G PGP+GEPG P G++G G G+PGLPG PG+ G GPPG Sbjct: 171 IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPG 229 Query: 95 MP-----GVPGPMGIPGEPGEEG 112 +P G PG G+PG PG++G Sbjct: 230 LPGPAGLGKPGLDGLPGAPGDKG 252 Score = 91.3 bits (225), Expect = 7e-19 Identities = 59/128 (46%), Positives = 66/128 (51%), Gaps = 18/128 (14%) Query: 3 VGPSSLPHLGLKLLLLLLLLP--LRGQ----ANTGCYGIPGMPGLPGAPG--KDGYDGLP 54 VGP G L + L LLP L+G+ G G PG PG PG PG K G G P Sbjct: 52 VGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQP 111 Query: 55 GPKGEPGI--------PAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMG--I 104 GP G PG P +PG GP GQ G G PG G G GPPG PG+PGP G I Sbjct: 112 GPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITI 171 Query: 105 PGEPGEEG 112 PG+PG +G Sbjct: 172 PGKPGAQG 179 Score = 91.3 bits (225), Expect = 7e-19 Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 4/93 (4%) Query: 24 LRG-QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI---PAIPGIRGPKGQKGEPG 79 +RG Q +G G PG+PG G PG G G GPKGEPG P PG+ G GQKG+ G Sbjct: 392 IRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLG 451 Query: 80 LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 LPG PG GP G PG+ G GP+G G PG +G Sbjct: 452 LPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKG 484 Score = 89.7 bits (221), Expect = 2e-18 Identities = 48/96 (50%), Positives = 55/96 (57%), Gaps = 9/96 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE------PGIPAIPGIRGPKGQKGEPGLPGH- 83 G G+ G PGLPG+ G G G PGPKGE PG+P I G +GP G G+PG+PG Sbjct: 352 GPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGER 411 Query: 84 --PGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 PG +GP GP G G PG G PG PG G QK Sbjct: 412 GLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQK 447 Score = 89.0 bits (219), Expect = 3e-18 Identities = 46/95 (48%), Positives = 54/95 (56%), Gaps = 7/95 (7%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKG--EPGIPAIPGIRGPKGQKGEPGLP- 81 RG G PG+PG PG G G GLPGP G +PG+ +PG G KG+ G PG+P Sbjct: 202 RGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPG 261 Query: 82 --GHPGKNGPMGPPGMP--GVPGPMGIPGEPGEEG 112 G PG GP GPPG+ GVPG G+PG G G Sbjct: 262 PRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSG 296 Score = 87.4 bits (215), Expect = 1e-17 Identities = 52/118 (44%), Positives = 63/118 (53%), Gaps = 30/118 (25%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP--------------GIP---AIP 66 L G A G G+ G+PG PG G+ G G+PGP+GEP G+P +P Sbjct: 230 LPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLP 289 Query: 67 GIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVP------GPMGIP------GEPGEEG 112 G +GP G KGEPG G PG GP G GMPG+P GP G+P GEPGE+G Sbjct: 290 GPQGPSGAKGEPGTRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDG 346 Score = 87.0 bits (214), Expect = 1e-17 Identities = 50/106 (47%), Positives = 55/106 (51%), Gaps = 7/106 (6%) Query: 25 RGQANT-GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE------ 77 RG A G G G PG G PG+ G GL GP G PG +PG RGP G KGE Sbjct: 327 RGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGP 386 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFT 123 PG+PG G GP G G PGVPG G+PG G G K + FT Sbjct: 387 PGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFT 432 Score = 86.3 bits (212), Expect = 2e-17 Identities = 42/83 (50%), Positives = 51/83 (61%), Gaps = 3/83 (3%) Query: 33 YGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH---PGKNGP 89 YG+PG+PG G G G GL G +GEPG PG +GP+G G PGLPG PG+ GP Sbjct: 315 YGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGP 374 Query: 90 MGPPGMPGVPGPMGIPGEPGEEG 112 GP G G GP G+PG G++G Sbjct: 375 PGPKGEAGPGGPPGVPGIRGDQG 397 Score = 83.2 bits (204), Expect = 2e-16 Identities = 44/97 (45%), Positives = 52/97 (53%), Gaps = 11/97 (11%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHP 84 +G+A G G PG+PG+ G G G G PG GE G+P G GP G KGEPG G P Sbjct: 378 KGEAGPG--GPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRP 435 Query: 85 G---------KNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G + G +G PG PG+ GP GIPG G G Sbjct: 436 GGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAG 472 Score = 80.9 bits (198), Expect = 9e-16 Identities = 44/91 (48%), Positives = 50/91 (54%), Gaps = 5/91 (5%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYD--GLPGPKGEPGIPAIPGI---RGPKGQKGEPGLP 81 Q +G G PG G PG G GY GLPGPKG+ G +PG+ RG G+ GEPG Sbjct: 292 QGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQ 351 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G G GP G PG G+PG G PG GE G Sbjct: 352 GPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG 382 Score = 77.4 bits (189), Expect = 1e-14 Identities = 40/100 (40%), Positives = 52/100 (52%), Gaps = 11/100 (11%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPA-----IPGIRGPKGQKGEPG 79 +G G+PG GLPG G G G PG +G PG+ +PG+ GPKG +G G Sbjct: 272 KGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAG 331 Query: 80 LPG------HPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 +PG PG++G G G G+ GP G+PG G GR Sbjct: 332 VPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGR 371 Score = 67.0 bits (162), Expect = 1e-11 Identities = 55/153 (35%), Positives = 65/153 (42%), Gaps = 30/153 (19%) Query: 15 LLLLLLLLPL----RGQANTGCYGIPGMP-------------GLPGAPGKDGYDGLPGP- 56 LLLLLL+L L R + G G G G P GK Y +P P Sbjct: 11 LLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPL 70 Query: 57 -----KGEPGIPAIPGIRGPKGQKGEPGLPGHP-----GKNGPMGPPGMP--GVPGPMGI 104 KGEPG P PG RGP G G PG PG G+ GP GPPG G GP G+ Sbjct: 71 LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGL 130 Query: 105 PGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSL 137 PG+ G G+ + + + PP P L Sbjct: 131 PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGL 163 Score = 62.0 bits (149), Expect = 5e-10 Identities = 45/108 (41%), Positives = 55/108 (50%), Gaps = 6/108 (5%) Query: 9 PHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGA----PGKDGYDGLPGPKGEPGIPA 64 P L LLLL+L+L +A++G G G G P + G G P +G+ Sbjct: 7 PLSSLLLLLLVLVLGCGPRASSGG-GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLE 65 Query: 65 IPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 +P P KGEPG PG PG GP GPPG PG PG MG PG G+ G Sbjct: 66 MPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG-MGKPGLHGQPG 112 >gi|56606142 complement component 1, q subcomponent-like 4 [Homo sapiens] Length = 238 Score = 121 bits (303), Expect = 6e-28 Identities = 85/246 (34%), Positives = 121/246 (49%), Gaps = 24/246 (9%) Query: 15 LLLLLLLLPL-----RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIR 69 +LLLL+ +PL RG A+ G M P P G DG P P P PG + Sbjct: 2 VLLLLVAIPLLVHSSRGPAHYEMLGRCRMVCDPHGPRGPGPDGAPA--SVPPFP--PGAK 57 Query: 70 GPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG-----RYKQKFQSVFTV 124 G G++G+ GL G PG GP GPPG PG PGP G PG PG G Y + + + Sbjct: 58 GEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPG-PGPGGVAPAAGYVPRI-AFYAG 115 Query: 125 TRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYH-----ASHTANLC 179 R+ H+ ++RF+ V+TN Y+ ++GKFTC +PG+Y+F YH T+ Sbjct: 116 LRRPHE---GYEVLRFDDVVTNVGNAYEAASGKFTCPMPGVYFFAYHVLMRGGDGTSMWA 172 Query: 180 VLLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSG 239 L+ V+ + S V+L L VG+EV++ ++ G S FSG Sbjct: 173 DLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLDGGKVHGGNTNKYSTFSG 232 Query: 240 FLLFPD 245 F+++PD Sbjct: 233 FIIYPD 238 >gi|58801559 complement component 1, q subcomponent-like 3 [Homo sapiens] Length = 255 Score = 113 bits (283), Expect = 1e-25 Identities = 83/269 (30%), Positives = 118/269 (43%), Gaps = 53/269 (19%) Query: 15 LLLLLLLLP-------------LRGQANTGC--YGIPGMPGLPGAPGKDGYDGLP----G 55 +LLL++L+P + G C YG P P + LP G Sbjct: 2 VLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQG 61 Query: 56 PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYK 115 PKGE G P G RGP G+ G P GPMGPPG G PG G+PG PG G Sbjct: 62 PKGEAGRPGKAGPRGPPGEPGPP---------GPMGPPGEKGEPGRQGLPGPPGAPGLNA 112 Query: 116 QKFQSVFTVT-----------RQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPG 164 S T + ++ H+ +++F+ V+TN YD +TGKFTC +PG Sbjct: 113 AGAISAATYSTVPKIAFYAGLKRQHE---GYEVLKFDDVVTNLGNHYDPTTGKFTCSIPG 169 Query: 165 LYYFVYH--------ASHTANLCVLLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEE 216 +Y+F YH S A+LC + V+ + S V+L L+ G+E Sbjct: 170 IYFFTYHVLMRGGDGTSMWADLC---KNNQVRASAIAQDADQNYDYASNSVVLHLEPGDE 226 Query: 217 VWLAVNDYYDMVGIQGSDSVFSGFLLFPD 245 V++ ++ G S FSGF+++ D Sbjct: 227 VYIKLDGGKAHGGNNNKYSTFSGFIIYAD 255 >gi|154937344 complement component 1, q subcomponent-like 2 [Homo sapiens] Length = 287 Score = 113 bits (283), Expect = 1e-25 Identities = 75/224 (33%), Positives = 105/224 (46%), Gaps = 19/224 (8%) Query: 36 PGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMG-PPG 94 P P + G G G G PGP+G PG P PG RGP G+KG+ G PG PG G G Sbjct: 69 PPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTAGTASG 128 Query: 95 MPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTR-----QTHQPPAPNSLIRFNAVLTNPQG 149 + V G G+ G+ EG + F+ + P +++F+ V+TN Sbjct: 129 VGVVGGGAGVGGD--SEGEVTSALSATFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGN 186 Query: 150 DYDTSTGKFTCKVPGLYYFVYH--------ASHTANLCVLLYRSGVKVVTFCGHTSKTNQ 201 YD +TGKF+C+V G+Y+F YH S A+LC V+ + Sbjct: 187 HYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLC---KNGQVRASAIAQDADQNYD 243 Query: 202 VNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGFLLFPD 245 S V+L L G+EV++ ++ G S FSGFLL+PD Sbjct: 244 YASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD 287 Score = 48.1 bits (113), Expect = 7e-06 Identities = 39/105 (37%), Positives = 47/105 (44%), Gaps = 10/105 (9%) Query: 11 LGLKLLLLLLLLPL-RGQANTGCYGIPGMPGLP--GAPGKDGYDGLPGPKGEPGIPAIPG 67 LGL + + LLL RG A+ G M P APG + PG K +P P+ Sbjct: 3 LGLLIAVPLLLQAAPRGAAHYEMMGTCRMICDPYTAAPGGEP----PGAKAQPPGPSTAA 58 Query: 68 IRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 + + P P GP G PG PG PGP G PGEPG G Sbjct: 59 LEVMQDLSANPP---PPFIQGPKGDPGRPGKPGPRGPPGEPGPPG 100 >gi|5729785 complement component 1, q subcomponent-like 1 [Homo sapiens] Length = 258 Score = 108 bits (270), Expect = 4e-24 Identities = 75/230 (32%), Positives = 106/230 (46%), Gaps = 37/230 (16%) Query: 42 PGAPGK-DGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPG 100 PGA + DG D L G P P ++GP+G+ PG GK GP GPPG PG PG Sbjct: 40 PGAGARTDGGDALSEQSGAP--PPSTLVQGPQGK------PGRTGKPGPPGPPGDPGPPG 91 Query: 101 PMGIPGEPGEEGRYKQK-------FQSVFTVTRQT----------HQPPAPNSLIRFNAV 143 P+G PGE GE G+ ++ T T T P +++F+ V Sbjct: 92 PVGPPGEKGEPGKPGPPGLPGAGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDV 151 Query: 144 LTNPQGDYDTSTGKFTCKVPGLYYFVYH--------ASHTANLCVLLYRSGVKVVTFCGH 195 +TN +YD ++GKFTC +PG Y+F YH S A+LC V+ Sbjct: 152 VTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLC---KNGQVRASAIAQD 208 Query: 196 TSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGFLLFPD 245 + S V+L L G+EV++ ++ G S FSGF+++ D Sbjct: 209 ADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD 258 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 102 bits (255), Expect = 2e-22 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 12/96 (12%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMG-- 91 G PG+PG+PG G GY GLPG G+PG+ PG+ GP G KG PGLPG PG GP G Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026 Query: 92 ----------PPGMPGVPGPMGIPGEPGEEGRYKQK 117 P G+ G PGP G+PG+PG G QK Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062 Score = 102 bits (255), Expect = 2e-22 Identities = 46/88 (52%), Positives = 54/88 (61%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHP 84 +G G+PG+PG G PG GY G PG KG G P +PG+ G G KG+PGLPG P Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124 Query: 85 GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G GP GP G+ G PG G+PGEPG G Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVG 1152 Score = 101 bits (252), Expect = 5e-22 Identities = 57/112 (50%), Positives = 65/112 (58%), Gaps = 11/112 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G PG+PGLPG PG+DG GLPGPKGEPG G RGP G PGLPG PG GPM Sbjct: 564 GSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP---PGNPGLPGLPGNIGPM 620 Query: 91 GPPGMPGVPGPM------GIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNS 136 GPPG G PGP+ G+ G PG+ G K T+T Q +P P + Sbjct: 621 GPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT-QPGKPGLPGN 670 Score = 100 bits (248), Expect = 2e-21 Identities = 58/120 (48%), Positives = 66/120 (55%), Gaps = 10/120 (8%) Query: 36 PGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP--GLPGHPGKN---GPM 90 PG PGLPG PG+DG GLPG G PG P +PGI G KG+ G P GLPG PG G Sbjct: 662 PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721 Query: 91 GPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGD 150 GPPG PG PG +G+ G PG G K + F + PP P L F L P+GD Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----GPPGPPGLPGFKGAL-GPKGD 776 Score = 99.4 bits (246), Expect = 3e-21 Identities = 46/87 (52%), Positives = 54/87 (62%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPG 85 G A G G PG G PG PG G+ GLPGP+G PG+P GI+G KG G+PGLPG PG Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1303 Query: 86 KNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G GPPG+ G PG G+ G G+ G Sbjct: 1304 LKGDQGPPGLQGNPGRPGLNGMKGDPG 1330 Score = 97.1 bits (240), Expect = 1e-20 Identities = 48/94 (51%), Positives = 53/94 (56%), Gaps = 12/94 (12%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G GI G PGLPG PG G G+PG G PG IPG G KG++G PG PG PG GP Sbjct: 87 GPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPP 146 Query: 91 GPPGMPG------------VPGPMGIPGEPGEEG 112 GPPG+PG +PGP G PG PG G Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180 Score = 96.7 bits (239), Expect = 2e-20 Identities = 45/82 (54%), Positives = 51/82 (62%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G+PG PG PG G+ G G PGPKG PG+P PG+ GP G KG G G PG G Sbjct: 982 GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 GPPG GVPG G PG PG++G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKG 1063 Score = 95.5 bits (236), Expect = 4e-20 Identities = 48/100 (48%), Positives = 57/100 (57%), Gaps = 17/100 (17%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGP--------------KGEPGIPAIPGIRGPK 72 + + G G PG+PG G G G GLPGP KGEPG+P IPG+ GPK Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 73 GQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G +G PG PG PG + G PG+PG PGP G PG PG+ G Sbjct: 982 GYQGLPGDPGQPGLS---GQPGLPGPPGPKGNPGLPGQPG 1018 Score = 95.5 bits (236), Expect = 4e-20 Identities = 45/90 (50%), Positives = 51/90 (56%), Gaps = 11/90 (12%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGE-----------PGIPAIPGIRGPKGQKGEPGLPG 82 G PG PG PG GK G DG+PGP G+ PG P +PG+ G KG G PG+PG Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 +PG GP G PG G PG G PG PG G Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244 Score = 94.7 bits (234), Expect = 6e-20 Identities = 48/91 (52%), Positives = 52/91 (57%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPG------HP 84 G G PG+PGLPG PG G GLPG G PG P GI GP G G PG PG HP Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157 Query: 85 GKNGP---MGPPGMPGVPGPMGIPGEPGEEG 112 G+ GP G PG G+PGP G GEPG+ G Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188 Score = 94.4 bits (233), Expect = 8e-20 Identities = 50/96 (52%), Positives = 58/96 (60%), Gaps = 14/96 (14%) Query: 31 GCYGIPGMPGLPGAPGKDGYDG---LPGP------KGEPGIPAIPG-----IRGPKGQKG 76 G GIPG G+PG G DG G LPGP KGEPG+P PG + G KG+KG Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 EPGLPG PG +GP G G+PG PG G+ G+PG G Sbjct: 968 EPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003 Score = 94.4 bits (233), Expect = 8e-20 Identities = 50/111 (45%), Positives = 58/111 (52%), Gaps = 11/111 (9%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPA---IPGIRGPKGQKGEPGLPGH 83 + + G GIPG PGL G PG G GLPGP G PG P +PG G G+KG+PGLPG Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ 1437 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAP 134 PG G GPPG G+ GP G PG F +TR + AP Sbjct: 1438 PGTRGLDGPPGPDGLQGPPGPPG--------TSSVAHGFLITRHSQTTDAP 1480 Score = 94.0 bits (232), Expect = 1e-19 Identities = 50/103 (48%), Positives = 59/103 (57%), Gaps = 7/103 (6%) Query: 17 LLLLLLPLRGQAN--TGCYGI-PGMP----GLPGAPGKDGYDGLPGPKGEPGIPAIPGIR 69 L LL L L GQ CYG PG G+ G G+ G+ GL G G PG P G Sbjct: 12 LFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPP 71 Query: 70 GPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GP+GQKG+ G+PG PG G GPPG+PG PG G+PG PG +G Sbjct: 72 GPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDG 114 Score = 94.0 bits (232), Expect = 1e-19 Identities = 44/79 (55%), Positives = 50/79 (63%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G PG+ G PG PG G +G PGP+G+ G IPG GPKG +G PGLPG PG G G P Sbjct: 51 GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110 Query: 94 GMPGVPGPMGIPGEPGEEG 112 G G PGP GIPG G +G Sbjct: 111 GHDGAPGPQGIPGCNGTKG 129 Score = 93.2 bits (230), Expect = 2e-19 Identities = 50/105 (47%), Positives = 56/105 (53%), Gaps = 17/105 (16%) Query: 25 RGQANTGCYGIPGMPGLP---------GAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK 75 +G+ +G PG PGLP G PG G GLPGPKGEPG PG++GP G Sbjct: 1181 KGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPP 1240 Query: 76 GEPG--LPGHPGKNGPMGPPGMP------GVPGPMGIPGEPGEEG 112 G PG L G G GP GPPG P G+PGP G PG PG G Sbjct: 1241 GSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGG 1285 Score = 92.4 bits (228), Expect = 3e-19 Identities = 48/105 (45%), Positives = 56/105 (53%), Gaps = 24/105 (22%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKN--- 87 G G PG PG PG G+ G+ LPGP G PG+P G GPKG +G PG PG PG+ Sbjct: 734 GLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD 792 Query: 88 ---------------GPMGPPGMPGV-----PGPMGIPGEPGEEG 112 GPMGPPG+PG+ PGP GIPG G+ G Sbjct: 793 GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837 Score = 92.0 bits (227), Expect = 4e-19 Identities = 46/92 (50%), Positives = 52/92 (56%), Gaps = 6/92 (6%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP------GLPGHPGKN 87 G PG PG PG G G G+PG KGEPG + + GPKG G P GLPG G Sbjct: 132 GFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP 191 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQ 119 GP+GPPG PG+ GP G PG PG +G FQ Sbjct: 192 GPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223 Score = 92.0 bits (227), Expect = 4e-19 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 9/88 (10%) Query: 34 GIPGMPGLPGA------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK---GEPGLPGHP 84 G+PG PG PG PG G G PG KG+PG+P PG GP G K G PG PG P Sbjct: 1086 GLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145 Query: 85 GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G+ GP+G G PG PGP G G+PG++G Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173 Score = 92.0 bits (227), Expect = 4e-19 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 11/93 (11%) Query: 31 GCYGIPGMPGLPGAPGK---DGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH---- 83 G G PG PGLPG PG G+ G PGP GE G P GI GP GQKGEPG PG Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 84 ----PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG +G G G+PG+PG G+PG GE G Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG 1226 Score = 90.9 bits (224), Expect = 9e-19 Identities = 47/105 (44%), Positives = 58/105 (55%), Gaps = 19/105 (18%) Query: 27 QANTGCYGIPGMPGL------PGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGL 80 + N G G+PG+PGL PG G G GL G KG+PG+P +PG G KG G PG Sbjct: 1290 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1349 Query: 81 PGHPGKNGPMGPPGMPGVPGPM-------------GIPGEPGEEG 112 G G+ G +GPPG PG+PGP GIPG+PG +G Sbjct: 1350 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1394 Score = 90.1 bits (222), Expect = 2e-18 Identities = 53/118 (44%), Positives = 60/118 (50%), Gaps = 15/118 (12%) Query: 3 VGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGL--PGPKGEP 60 +GP LP +G++ P G G PG+ G+PG G G GL PGP GE Sbjct: 810 MGPPGLPGIGVQG-------PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862 Query: 61 GIPAIPGIRGPKGQKGEPGLP------GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G P IPG GP G G PGLP G PG G MG G PG PGP+GIPG G G Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920 Score = 89.4 bits (220), Expect = 3e-18 Identities = 49/97 (50%), Positives = 54/97 (55%), Gaps = 15/97 (15%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGP------KGQKGEPG-- 79 G G+PGMPG GAPG G G G KGE PG P PG++GP G KGEPG Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161 Query: 80 ----LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 LPG G G GPPG+ G+PGP GIPG G G Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Score = 89.0 bits (219), Expect = 3e-18 Identities = 54/135 (40%), Positives = 65/135 (48%), Gaps = 29/135 (21%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGK-------------DGYDGLPGPKGEPGIPAIPGIRG 70 L Q G G G+ G PG PG+ G GLPG +G PG P I G G Sbjct: 220 LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPG 279 Query: 71 P-------KGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFT 123 P KG++GEPG G PGK+G G PG+PG+PG G PGEPG +G QK + Sbjct: 280 PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT--- 336 Query: 124 VTRQTHQPPAPNSLI 138 PP P L+ Sbjct: 337 ------GPPGPPGLV 345 Score = 89.0 bits (219), Expect = 3e-18 Identities = 44/93 (47%), Positives = 52/93 (55%), Gaps = 11/93 (11%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGI---------RGPKGQKGEPGLP 81 G G PG+PG PG PG G G+ GP G PG+P PG GP G+KG+PG Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172 Query: 82 GHPGKNGPMGPPGMPGV--PGPMGIPGEPGEEG 112 G PG G G PG PG PGP G+PG G++G Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205 Score = 88.6 bits (218), Expect = 5e-18 Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 8/87 (9%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G PG+PG+ G PG LPGPKG PG P PGI+G G G PG G PG G MGPP Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206 Query: 94 GMPGVPGP--------MGIPGEPGEEG 112 G PG+PGP G GE GE+G Sbjct: 207 GPPGLPGPKGNMGLNFQGPKGEKGEQG 233 Score = 88.6 bits (218), Expect = 5e-18 Identities = 48/99 (48%), Positives = 53/99 (53%), Gaps = 19/99 (19%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLP------------GPKGEPGIPAIPGIRGPKGQKGE 77 TG G PG PGLPG PG G G P GPKG PGIP PG G G KGE Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546 Query: 78 PG----LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG PG G G +G PG PG+P G+PG PG++G Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLP---GLPGTPGQDG 582 Score = 88.6 bits (218), Expect = 5e-18 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 18/107 (16%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG--IRGPKGQKGEPGL 80 L GQ + G GIPG PGLPG G+ G+ G PG +G PG P PG + GPKG G G Sbjct: 1200 LSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGP 1259 Query: 81 PGHPGKNG------PMGPPGMPGV---------PGPMGIPGEPGEEG 112 PG PG G P GPPG+PG PG G+PG PG +G Sbjct: 1260 PGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1306 Score = 86.7 bits (213), Expect = 2e-17 Identities = 49/108 (45%), Positives = 60/108 (55%), Gaps = 23/108 (21%) Query: 25 RGQAN-TGCYGIPGMPGLPGAPGKDG----------YDGLPGPKGE---PGIPAIPGIRG 70 +GQA TG G+PG+PG PGAPG G + G+ G KGE PG P +PG+ G Sbjct: 517 KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576 Query: 71 PKGQKGEPGLPG---------HPGKNGPMGPPGMPGVPGPMGIPGEPG 109 GQ G PGLPG G+ GP G PG+PG+PG +G G PG Sbjct: 577 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624 Score = 86.3 bits (212), Expect = 2e-17 Identities = 41/86 (47%), Positives = 47/86 (54%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 + + G G PG G PG G+ G DG+PGP G GI PG+ G G G PG+PGH G Sbjct: 56 EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGA 115 Query: 87 NGPMGPPGMPGVPGPMGIPGEPGEEG 112 GP G PG G G G PG PG G Sbjct: 116 PGPQGIPGCNGTKGERGFPGSPGFPG 141 Score = 85.9 bits (211), Expect = 3e-17 Identities = 46/102 (45%), Positives = 53/102 (51%), Gaps = 20/102 (19%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---------------PGIPAIPGIRGPKGQK 75 G G G PG PG PGK G G PG KGE PG +PG++G G + Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 76 GEPGLPGHPGKNGPMGPPGMPGVPGPM-----GIPGEPGEEG 112 G+PGLPG G+ G G PG+PG PGPM G GE GE G Sbjct: 929 GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Score = 85.5 bits (210), Expect = 4e-17 Identities = 47/98 (47%), Positives = 56/98 (57%), Gaps = 18/98 (18%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK-------GQKGEPGLPGHPGK 86 GIPG+PG PG PG+ G DG G KG+ G P PG+ P+ G+KG GLPG PG+ Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 87 NGP------MGPPGMPGVP-----GPMGIPGEPGEEGR 113 G GPPG+PG P GP G PG PGE G+ Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQ 407 Score = 85.1 bits (209), Expect = 5e-17 Identities = 44/86 (51%), Positives = 49/86 (56%), Gaps = 9/86 (10%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP---- 89 G PG PGLPG PG G G PG +G PG P G+ G KG G PG+PG PG GP Sbjct: 1291 GNPGQPGLPGLPGLKGDQGPPGLQGNPGRP---GLNGMKGDPGLPGVPGFPGMKGPSGVP 1347 Query: 90 --MGPPGMPGVPGPMGIPGEPGEEGR 113 GP G PG+ GP G PG PG G+ Sbjct: 1348 GSAGPEGEPGLIGPPGPPGLPGPSGQ 1373 Score = 84.7 bits (208), Expect = 7e-17 Identities = 43/98 (43%), Positives = 52/98 (53%), Gaps = 15/98 (15%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG---------------Q 74 TG G+PG G PG PG G G G G+PG+P +PG++G +G Sbjct: 1266 TGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1325 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 KG+PGLPG PG G GP G+PG GP G PG G G Sbjct: 1326 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG 1363 Score = 84.3 bits (207), Expect = 9e-17 Identities = 46/98 (46%), Positives = 52/98 (53%), Gaps = 16/98 (16%) Query: 31 GCYGIPGMPG--LPGAPGKDGYDGLPGPKGEPGIPAI---------PGIRGPKGQ----- 74 G G PG+PG LPG PG G+ G+PGP G PG P PG GPKG+ Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG PG PG G +GP G G PGP G PG G +G Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG 793 Score = 83.6 bits (205), Expect = 1e-16 Identities = 53/128 (41%), Positives = 62/128 (48%), Gaps = 19/128 (14%) Query: 2 DVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP----- 56 D GP P GL + + + + N G G+PG G G PG G GLPGP Sbjct: 335 DTGPPGPP--GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV 392 Query: 57 KGEPGIPAIPGIRGPKGQKGEPG--LPGHPGKNGPMGPPGMPGVPGPMG----------I 104 G PG P PG RG KG +G PG +PG PG +G G PG+PG PGP G Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 105 PGEPGEEG 112 PG PG G Sbjct: 453 PGPPGPPG 460 Score = 83.6 bits (205), Expect = 1e-16 Identities = 51/138 (36%), Positives = 62/138 (44%), Gaps = 49/138 (35%) Query: 25 RGQANTGCYGIPGMPGL------------------PGAPGKDGYDGLPGPKGE------- 59 +G+ G PG PGL PG PG+ G DGLPGPKG+ Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP 807 Query: 60 -----PGIPAI-----------------PGIRGPKGQKGEPGLPG--HPGKNGPMGPPGM 95 PG+P I PG+ G G+KG+PG PG PG G G PG+ Sbjct: 808 GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867 Query: 96 PGVPGPMGIPGEPGEEGR 113 PG PGP+G PG PG G+ Sbjct: 868 PGAPGPIGPPGSPGLPGK 885 Score = 82.8 bits (203), Expect = 2e-16 Identities = 52/130 (40%), Positives = 58/130 (44%), Gaps = 26/130 (20%) Query: 34 GIPGMPGLPGA------------------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK 75 G G PGLPG PG G +G PGP G PG P PG+ G KG K Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 76 GEPGLP--GHPGKNGPMGPPGMPGVPGPMGI------PGEPGEEGRYKQKFQSVFTVTRQ 127 G+PG+ G PG GP G PG+PG PG GI PG PG G K Q Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125 Query: 128 THQPPAPNSL 137 T PP P + Sbjct: 1126 TPGPPGPKGI 1135 Score = 81.6 bits (200), Expect = 6e-16 Identities = 43/102 (42%), Positives = 50/102 (49%), Gaps = 19/102 (18%) Query: 27 QANTGCYGIPGMPGLPGA----------------PGKDGYDGLPGPKGEPGIPAIPGIRG 70 + G G PG PGLPG PG+ G GLPGP+G G +PG G Sbjct: 1353 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTG 1409 Query: 71 PKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 P G G GLPG G G G PG+PG PG G+ G PG +G Sbjct: 1410 PPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1451 Score = 81.3 bits (199), Expect = 7e-16 Identities = 47/99 (47%), Positives = 53/99 (53%), Gaps = 17/99 (17%) Query: 31 GCYGIPGMPGLPGA-----PGKDGYDGLPGPKGEPGIP--AIPGIRGPKGQKGEPGLPGH 83 G G PG+PG PGA PG G+ G G KG+ G P +IPG G GQ G PGLPG Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436 Query: 84 PGKNGP----------MGPPGMPGVPGPMGIPGEPGEEG 112 PG GP GPPG PG PG G+ GE G +G Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKG 475 Score = 81.3 bits (199), Expect = 7e-16 Identities = 40/92 (43%), Positives = 48/92 (52%), Gaps = 13/92 (14%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGE-------------PGIPAIPGIRGPKGQKGEPGL 80 G PG PG PG G G G+ G KG+ PG P +PG+ GP G G PG Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513 Query: 81 PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G G+ G GP G+PG+PG G PG PG +G Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Score = 80.9 bits (198), Expect = 9e-16 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 23/102 (22%) Query: 35 IPGMPGLPGAPGKDGYDGLPGPKG----------EPGIPAIPGIRGPKGQKGEPGLPGHP 84 IPG PGL G PG G G PGP G EPG P PG G KG +GE G+ G Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 85 GK----------NGPMGPPGMPGVPGP---MGIPGEPGEEGR 113 G +GP G PG+PG+PGP +G PG+ GE+G+ Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519 Score = 80.5 bits (197), Expect = 1e-15 Identities = 47/113 (41%), Positives = 58/113 (51%), Gaps = 24/113 (21%) Query: 24 LRGQAN-TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI---------PAIPGIRGPKG 73 L G+A +G G G G+ G PG G G+PG G PG+ P +PG G KG Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 74 QKGEPGLPGHP--------GKNGPMGPPGMPGVPGP------MGIPGEPGEEG 112 KGEPGLPG P G G G PG+PG+PG G+PG+PG+ G Sbjct: 942 SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPG 994 Score = 79.7 bits (195), Expect = 2e-15 Identities = 42/93 (45%), Positives = 48/93 (51%), Gaps = 14/93 (15%) Query: 31 GCYGIPGMPGLPGAPGKD-----------GYDGLPGPKGEPGIPAIPGIRGPKGQKGEPG 79 G +GIPG G PG PG D G G PGP G PG P +P G G G PG Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP---GKAGASGFPG 893 Query: 80 LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G G GP GPPG G+PG G+PG G++G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDG 926 Score = 77.8 bits (190), Expect = 8e-15 Identities = 39/96 (40%), Positives = 46/96 (47%), Gaps = 19/96 (19%) Query: 36 PGMPGLPGAPGKDGYDG-------------------LPGPKGEPGIPAIPGIRGPKGQKG 76 PG PG PG+PG G G + GP G+PG+P +PG G G G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 + G G G GP G PG+PG PG G PG GE G Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548 Score = 75.1 bits (183), Expect = 5e-14 Identities = 44/112 (39%), Positives = 52/112 (46%), Gaps = 26/112 (23%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYD-------------GLPGPKGEPGIPAIPGIRGPKG 73 Q G G PG PG+ G PG G + G PG GE G P IPG+ G G Sbjct: 260 QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319 Query: 74 QKGEPGLPGHPGKNGPMGPPGMPGV-------------PGPMGIPGEPGEEG 112 GEPG G G+ G GPPG PG+ G +G+PG PGE+G Sbjct: 320 YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKG 371 Score = 60.5 bits (145), Expect = 1e-09 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 17/97 (17%) Query: 2 DVGPSSLP-HLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 60 D GP +P GLK L P Q G G PG PG G P G+DG G KG+P Sbjct: 1380 DAGPPGIPGQPGLKGLPG----PQGPQGLPGPTGPPGDPGRNGLP---GFDGAGGRKGDP 1432 Query: 61 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPG 97 G+P PG R GL G PG +G GPPG PG Sbjct: 1433 GLPGQPGTR---------GLDGPPGPDGLQGPPGPPG 1460 Score = 38.9 bits (89), Expect = 0.004 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 12/47 (25%) Query: 67 GIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 GI+G KG++G PGL GH PG+PG G G PG G+ Sbjct: 42 GIKGEKGERGFPGLEGH------------PGLPGFPGPEGPPGPRGQ 76 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 102 bits (255), Expect = 2e-22 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 12/96 (12%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP---- 89 G PG+PG+PG G GY GLPG G+PG+ PG+ GP G KG PGLPG PG GP Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026 Query: 90 --------MGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 GP G+ G PGP G+PG+PG G QK Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062 Score = 102 bits (255), Expect = 2e-22 Identities = 46/88 (52%), Positives = 54/88 (61%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHP 84 +G G+PG+PG G PG GY G PG KG G P +PG+ G G KG+PGLPG P Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124 Query: 85 GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G GP GP G+ G PG G+PGEPG G Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVG 1152 Score = 101 bits (252), Expect = 5e-22 Identities = 57/112 (50%), Positives = 65/112 (58%), Gaps = 11/112 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G PG+PGLPG PG+DG GLPGPKGEPG G RGP G PGLPG PG GPM Sbjct: 564 GSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP---PGNPGLPGLPGNIGPM 620 Query: 91 GPPGMPGVPGPM------GIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNS 136 GPPG G PGP+ G+ G PG+ G K T+T Q +P P + Sbjct: 621 GPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT-QPGKPGLPGN 670 Score = 100 bits (248), Expect = 2e-21 Identities = 58/120 (48%), Positives = 66/120 (55%), Gaps = 10/120 (8%) Query: 36 PGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP--GLPGHPGKN---GPM 90 PG PGLPG PG+DG GLPG G PG P +PGI G KG+ G P GLPG PG G Sbjct: 662 PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721 Query: 91 GPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGD 150 GPPG PG PG +G+ G PG G K + F + PP P L F L P+GD Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----GPPGPPGLPGFKGAL-GPKGD 776 Score = 99.8 bits (247), Expect = 2e-21 Identities = 50/99 (50%), Positives = 56/99 (56%), Gaps = 11/99 (11%) Query: 25 RGQANTGCYGIPGMPGLP---------GAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK 75 +G+ +G PG PGLP G PG G GLPGPKGEPG PG++GP G Sbjct: 1181 KGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPP 1240 Query: 76 GEPG--LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG L G G GP GPPG PG+PGP G PG PG G Sbjct: 1241 GSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGG 1279 Score = 97.1 bits (240), Expect = 1e-20 Identities = 48/94 (51%), Positives = 53/94 (56%), Gaps = 12/94 (12%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G GI G PGLPG PG G G+PG G PG IPG G KG++G PG PG PG GP Sbjct: 87 GPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPP 146 Query: 91 GPPGMPG------------VPGPMGIPGEPGEEG 112 GPPG+PG +PGP G PG PG G Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180 Score = 96.7 bits (239), Expect = 2e-20 Identities = 45/82 (54%), Positives = 51/82 (62%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G+PG PG PG G+ G G PGPKG PG+P PG+ GP G KG G G PG G Sbjct: 982 GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 GPPG GVPG G PG PG++G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKG 1063 Score = 96.3 bits (238), Expect = 2e-20 Identities = 50/98 (51%), Positives = 57/98 (58%), Gaps = 12/98 (12%) Query: 27 QANTGCYGIPGMPGLPGA---PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGL--- 80 + N G G PG PGLPG PG G G+ G KG PG P +PG+ G KG +G PGL Sbjct: 1251 KGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN 1310 Query: 81 PGHPGKNGPMGPPGMPGVP------GPMGIPGEPGEEG 112 PG PG NG G PG+PGVP GP G+PG G EG Sbjct: 1311 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEG 1348 Score = 95.5 bits (236), Expect = 4e-20 Identities = 48/100 (48%), Positives = 57/100 (57%), Gaps = 17/100 (17%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGP--------------KGEPGIPAIPGIRGPK 72 + + G G PG+PG G G G GLPGP KGEPG+P IPG+ GPK Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 73 GQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G +G PG PG PG + G PG+PG PGP G PG PG+ G Sbjct: 982 GYQGLPGDPGQPGLS---GQPGLPGPPGPKGNPGLPGQPG 1018 Score = 95.5 bits (236), Expect = 4e-20 Identities = 45/90 (50%), Positives = 51/90 (56%), Gaps = 11/90 (12%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGE-----------PGIPAIPGIRGPKGQKGEPGLPG 82 G PG PG PG GK G DG+PGP G+ PG P +PG+ G KG G PG+PG Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 +PG GP G PG G PG G PG PG G Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244 Score = 94.7 bits (234), Expect = 6e-20 Identities = 48/91 (52%), Positives = 52/91 (57%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP------GHP 84 G G PG+PGLPG PG G GLPG G PG P GI GP G G PG P GHP Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157 Query: 85 GKNGP---MGPPGMPGVPGPMGIPGEPGEEG 112 G+ GP G PG G+PGP G GEPG+ G Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188 Score = 94.4 bits (233), Expect = 8e-20 Identities = 50/96 (52%), Positives = 58/96 (60%), Gaps = 14/96 (14%) Query: 31 GCYGIPGMPGLPGAPGKDGYDG---LPGP------KGEPGIPAIPG-----IRGPKGQKG 76 G GIPG G+PG G DG G LPGP KGEPG+P PG + G KG+KG Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 EPGLPG PG +GP G G+PG PG G+ G+PG G Sbjct: 968 EPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003 Score = 94.4 bits (233), Expect = 8e-20 Identities = 50/111 (45%), Positives = 58/111 (52%), Gaps = 11/111 (9%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPA---IPGIRGPKGQKGEPGLPGH 83 + + G GIPG PGL G PG G GLPGP G PG P +PG G G+KG+PGLPG Sbjct: 1372 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ 1431 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAP 134 PG G GPPG G+ GP G PG F +TR + AP Sbjct: 1432 PGTRGLDGPPGPDGLQGPPGPPG--------TSSVAHGFLITRHSQTTDAP 1474 Score = 94.0 bits (232), Expect = 1e-19 Identities = 50/103 (48%), Positives = 59/103 (57%), Gaps = 7/103 (6%) Query: 17 LLLLLLPLRGQAN--TGCYGI-PGMP----GLPGAPGKDGYDGLPGPKGEPGIPAIPGIR 69 L LL L L GQ CYG PG G+ G G+ G+ GL G G PG P G Sbjct: 12 LFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPP 71 Query: 70 GPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GP+GQKG+ G+PG PG G GPPG+PG PG G+PG PG +G Sbjct: 72 GPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDG 114 Score = 94.0 bits (232), Expect = 1e-19 Identities = 44/79 (55%), Positives = 50/79 (63%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G PG+ G PG PG G +G PGP+G+ G IPG GPKG +G PGLPG PG G G P Sbjct: 51 GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110 Query: 94 GMPGVPGPMGIPGEPGEEG 112 G G PGP GIPG G +G Sbjct: 111 GHDGAPGPQGIPGCNGTKG 129 Score = 92.4 bits (228), Expect = 3e-19 Identities = 48/105 (45%), Positives = 56/105 (53%), Gaps = 24/105 (22%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKN--- 87 G G PG PG PG G+ G+ LPGP G PG+P G GPKG +G PG PG PG+ Sbjct: 734 GLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD 792 Query: 88 ---------------GPMGPPGMPGV-----PGPMGIPGEPGEEG 112 GPMGPPG+PG+ PGP GIPG G+ G Sbjct: 793 GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837 Score = 92.0 bits (227), Expect = 4e-19 Identities = 46/92 (50%), Positives = 52/92 (56%), Gaps = 6/92 (6%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP------GLPGHPGKN 87 G PG PG PG G G G+PG KGEPG + + GPKG G P GLPG G Sbjct: 132 GFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP 191 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQ 119 GP+GPPG PG+ GP G PG PG +G FQ Sbjct: 192 GPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223 Score = 92.0 bits (227), Expect = 4e-19 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 9/88 (10%) Query: 34 GIPGMPGLPGA------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK---GEPGLPGHP 84 G+PG PG PG PG G G PG KG+PG+P PG GP G K G PG PG P Sbjct: 1086 GLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145 Query: 85 GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G+ GP+G G PG PGP G G+PG++G Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173 Score = 92.0 bits (227), Expect = 4e-19 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 11/93 (11%) Query: 31 GCYGIPGMPGLPGAPGK---DGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH---- 83 G G PG PGLPG PG G+ G PGP GE G P GI GP GQKGEPG PG Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 84 ----PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG +G G G+PG+PG G+PG GE G Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG 1226 Score = 90.9 bits (224), Expect = 9e-19 Identities = 47/105 (44%), Positives = 58/105 (55%), Gaps = 19/105 (18%) Query: 27 QANTGCYGIPGMPGL------PGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGL 80 + N G G+PG+PGL PG G G GL G KG+PG+P +PG G KG G PG Sbjct: 1284 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1343 Query: 81 PGHPGKNGPMGPPGMPGVPGPM-------------GIPGEPGEEG 112 G G+ G +GPPG PG+PGP GIPG+PG +G Sbjct: 1344 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1388 Score = 90.1 bits (222), Expect = 2e-18 Identities = 53/118 (44%), Positives = 60/118 (50%), Gaps = 15/118 (12%) Query: 3 VGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGL--PGPKGEP 60 +GP LP +G++ P G G PG+ G+PG G G GL PGP GE Sbjct: 810 MGPPGLPGIGVQG-------PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862 Query: 61 GIPAIPGIRGPKGQKGEPGLP------GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G P IPG GP G G PGLP G PG G MG G PG PGP+GIPG G G Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920 Score = 89.7 bits (221), Expect = 2e-18 Identities = 48/93 (51%), Positives = 55/93 (59%), Gaps = 6/93 (6%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG--IRGPKGQKGEPGL 80 L GQ + G GIPG PGLPG G+ G+ G PG +G PG P PG + GPKG G G Sbjct: 1200 LSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGP 1259 Query: 81 PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 PG PG GP GP PG+PG GI GE G G+ Sbjct: 1260 PGRPGLPGPEGP---PGLPGNGGIKGEKGNPGQ 1289 Score = 89.4 bits (220), Expect = 3e-18 Identities = 49/97 (50%), Positives = 54/97 (55%), Gaps = 15/97 (15%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGP------KGQKGEPG-- 79 G G+PGMPG GAPG G G G KGE PG P PG++GP G KGEPG Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161 Query: 80 ----LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 LPG G G GPPG+ G+PGP GIPG G G Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Score = 89.0 bits (219), Expect = 3e-18 Identities = 54/135 (40%), Positives = 65/135 (48%), Gaps = 29/135 (21%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGK-------------DGYDGLPGPKGEPGIPAIPGIRG 70 L Q G G G+ G PG PG+ G GLPG +G PG P I G G Sbjct: 220 LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPG 279 Query: 71 P-------KGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFT 123 P KG++GEPG G PGK+G G PG+PG+PG G PGEPG +G QK + Sbjct: 280 PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT--- 336 Query: 124 VTRQTHQPPAPNSLI 138 PP P L+ Sbjct: 337 ------GPPGPPGLV 345 Score = 89.0 bits (219), Expect = 3e-18 Identities = 44/93 (47%), Positives = 52/93 (55%), Gaps = 11/93 (11%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGI---------RGPKGQKGEPGLP 81 G G PG+PG PG PG G G+ GP G PG+P PG GP G+KG+PG Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172 Query: 82 GHPGKNGPMGPPGMPGV--PGPMGIPGEPGEEG 112 G PG G G PG PG PGP G+PG G++G Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205 Score = 89.0 bits (219), Expect = 3e-18 Identities = 44/99 (44%), Positives = 53/99 (53%), Gaps = 17/99 (17%) Query: 31 GCYGIPGMPGLPGAPGKDG-----------------YDGLPGPKGEPGIPAIPGIRGPKG 73 G +G PG+ G PG PG G GLPGP+G PG+P GI+G KG Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKG 1285 Query: 74 QKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G+PGLPG PG G GPPG+ G PG G+ G G+ G Sbjct: 1286 NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPG 1324 Score = 88.6 bits (218), Expect = 5e-18 Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 8/87 (9%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G PG+PG+ G PG LPGPKG PG P PGI+G G G PG G PG G MGPP Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206 Query: 94 GMPGVPGP--------MGIPGEPGEEG 112 G PG+PGP G GE GE+G Sbjct: 207 GPPGLPGPKGNMGLNFQGPKGEKGEQG 233 Score = 88.6 bits (218), Expect = 5e-18 Identities = 48/99 (48%), Positives = 53/99 (53%), Gaps = 19/99 (19%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLP------------GPKGEPGIPAIPGIRGPKGQKGE 77 TG G PG PGLPG PG G G P GPKG PGIP PG G G KGE Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546 Query: 78 PG----LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG PG G G +G PG PG+P G+PG PG++G Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLP---GLPGTPGQDG 582 Score = 86.7 bits (213), Expect = 2e-17 Identities = 49/108 (45%), Positives = 60/108 (55%), Gaps = 23/108 (21%) Query: 25 RGQAN-TGCYGIPGMPGLPGAPGKDG----------YDGLPGPKGE---PGIPAIPGIRG 70 +GQA TG G+PG+PG PGAPG G + G+ G KGE PG P +PG+ G Sbjct: 517 KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576 Query: 71 PKGQKGEPGLPG---------HPGKNGPMGPPGMPGVPGPMGIPGEPG 109 GQ G PGLPG G+ GP G PG+PG+PG +G G PG Sbjct: 577 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624 Score = 86.3 bits (212), Expect = 2e-17 Identities = 41/86 (47%), Positives = 47/86 (54%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 + + G G PG G PG G+ G DG+PGP G GI PG+ G G G PG+PGH G Sbjct: 56 EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGA 115 Query: 87 NGPMGPPGMPGVPGPMGIPGEPGEEG 112 GP G PG G G G PG PG G Sbjct: 116 PGPQGIPGCNGTKGERGFPGSPGFPG 141 Score = 85.9 bits (211), Expect = 3e-17 Identities = 46/102 (45%), Positives = 53/102 (51%), Gaps = 20/102 (19%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---------------PGIPAIPGIRGPKGQK 75 G G G PG PG PGK G G PG KGE PG +PG++G G + Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 76 GEPGLPGHPGKNGPMGPPGMPGVPGPM-----GIPGEPGEEG 112 G+PGLPG G+ G G PG+PG PGPM G GE GE G Sbjct: 929 GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Score = 85.5 bits (210), Expect = 4e-17 Identities = 47/98 (47%), Positives = 56/98 (57%), Gaps = 18/98 (18%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK-------GQKGEPGLPGHPGK 86 GIPG+PG PG PG+ G DG G KG+ G P PG+ P+ G+KG GLPG PG+ Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 87 NGP------MGPPGMPGVP-----GPMGIPGEPGEEGR 113 G GPPG+PG P GP G PG PGE G+ Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQ 407 Score = 85.1 bits (209), Expect = 5e-17 Identities = 44/86 (51%), Positives = 49/86 (56%), Gaps = 9/86 (10%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP---- 89 G PG PGLPG PG G G PG +G PG P G+ G KG G PG+PG PG GP Sbjct: 1285 GNPGQPGLPGLPGLKGDQGPPGLQGNPGRP---GLNGMKGDPGLPGVPGFPGMKGPSGVP 1341 Query: 90 --MGPPGMPGVPGPMGIPGEPGEEGR 113 GP G PG+ GP G PG PG G+ Sbjct: 1342 GSAGPEGEPGLIGPPGPPGLPGPSGQ 1367 Score = 84.3 bits (207), Expect = 9e-17 Identities = 46/98 (46%), Positives = 52/98 (53%), Gaps = 16/98 (16%) Query: 31 GCYGIPGMPG--LPGAPGKDGYDGLPGPKGEPGIPAI---------PGIRGPKGQ----- 74 G G PG+PG LPG PG G+ G+PGP G PG P PG GPKG+ Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG PG PG G +GP G G PGP G PG G +G Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG 793 Score = 83.6 bits (205), Expect = 1e-16 Identities = 53/128 (41%), Positives = 62/128 (48%), Gaps = 19/128 (14%) Query: 2 DVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP----- 56 D GP P GL + + + + N G G+PG G G PG G GLPGP Sbjct: 335 DTGPPGPP--GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV 392 Query: 57 KGEPGIPAIPGIRGPKGQKGEPG--LPGHPGKNGPMGPPGMPGVPGPMG----------I 104 G PG P PG RG KG +G PG +PG PG +G G PG+PG PGP G Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 105 PGEPGEEG 112 PG PG G Sbjct: 453 PGPPGPPG 460 Score = 83.6 bits (205), Expect = 1e-16 Identities = 51/138 (36%), Positives = 62/138 (44%), Gaps = 49/138 (35%) Query: 25 RGQANTGCYGIPGMPGL------------------PGAPGKDGYDGLPGPKGE------- 59 +G+ G PG PGL PG PG+ G DGLPGPKG+ Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP 807 Query: 60 -----PGIPAI-----------------PGIRGPKGQKGEPGLPG--HPGKNGPMGPPGM 95 PG+P I PG+ G G+KG+PG PG PG G G PG+ Sbjct: 808 GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867 Query: 96 PGVPGPMGIPGEPGEEGR 113 PG PGP+G PG PG G+ Sbjct: 868 PGAPGPIGPPGSPGLPGK 885 Score = 82.8 bits (203), Expect = 2e-16 Identities = 52/130 (40%), Positives = 58/130 (44%), Gaps = 26/130 (20%) Query: 34 GIPGMPGLPGA------------------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK 75 G G PGLPG PG G +G PGP G PG P PG+ G KG K Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 76 GEPGLP--GHPGKNGPMGPPGMPGVPGPMGI------PGEPGEEGRYKQKFQSVFTVTRQ 127 G+PG+ G PG GP G PG+PG PG GI PG PG G K Q Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125 Query: 128 THQPPAPNSL 137 T PP P + Sbjct: 1126 TPGPPGPKGI 1135 Score = 82.4 bits (202), Expect = 3e-16 Identities = 43/101 (42%), Positives = 52/101 (51%), Gaps = 15/101 (14%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG------------- 73 Q G G+PG G PG PG G G G G+PG+P +PG++G +G Sbjct: 1257 QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1316 Query: 74 --QKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 KG+PGLPG PG G GP G+PG GP G PG G G Sbjct: 1317 NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG 1357 Score = 81.6 bits (200), Expect = 6e-16 Identities = 43/102 (42%), Positives = 50/102 (49%), Gaps = 19/102 (18%) Query: 27 QANTGCYGIPGMPGLPGA----------------PGKDGYDGLPGPKGEPGIPAIPGIRG 70 + G G PG PGLPG PG+ G GLPGP+G G +PG G Sbjct: 1347 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTG 1403 Query: 71 PKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 P G G GLPG G G G PG+PG PG G+ G PG +G Sbjct: 1404 PPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1445 Score = 81.3 bits (199), Expect = 7e-16 Identities = 47/99 (47%), Positives = 53/99 (53%), Gaps = 17/99 (17%) Query: 31 GCYGIPGMPGLPGA-----PGKDGYDGLPGPKGEPGIP--AIPGIRGPKGQKGEPGLPGH 83 G G PG+PG PGA PG G+ G G KG+ G P +IPG G GQ G PGLPG Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436 Query: 84 PGKNGP----------MGPPGMPGVPGPMGIPGEPGEEG 112 PG GP GPPG PG PG G+ GE G +G Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKG 475 Score = 81.3 bits (199), Expect = 7e-16 Identities = 40/92 (43%), Positives = 48/92 (52%), Gaps = 13/92 (14%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGE-------------PGIPAIPGIRGPKGQKGEPGL 80 G PG PG PG G G G+ G KG+ PG P +PG+ GP G G PG Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513 Query: 81 PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G G+ G GP G+PG+PG G PG PG +G Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Score = 80.9 bits (198), Expect = 9e-16 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 23/102 (22%) Query: 35 IPGMPGLPGAPGKDGYDGLPGPKG----------EPGIPAIPGIRGPKGQKGEPGLPGHP 84 IPG PGL G PG G G PGP G EPG P PG G KG +GE G+ G Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 85 GK----------NGPMGPPGMPGVPGP---MGIPGEPGEEGR 113 G +GP G PG+PG+PGP +G PG+ GE+G+ Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519 Score = 80.5 bits (197), Expect = 1e-15 Identities = 47/113 (41%), Positives = 58/113 (51%), Gaps = 24/113 (21%) Query: 24 LRGQAN-TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI---------PAIPGIRGPKG 73 L G+A +G G G G+ G PG G G+PG G PG+ P +PG G KG Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 74 QKGEPGLPGHP--------GKNGPMGPPGMPGVPGP------MGIPGEPGEEG 112 KGEPGLPG P G G G PG+PG+PG G+PG+PG+ G Sbjct: 942 SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPG 994 Score = 79.7 bits (195), Expect = 2e-15 Identities = 42/93 (45%), Positives = 48/93 (51%), Gaps = 14/93 (15%) Query: 31 GCYGIPGMPGLPGAPGKD-----------GYDGLPGPKGEPGIPAIPGIRGPKGQKGEPG 79 G +GIPG G PG PG D G G PGP G PG P +P G G G PG Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP---GKAGASGFPG 893 Query: 80 LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G G GP GPPG G+PG G+PG G++G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDG 926 Score = 77.8 bits (190), Expect = 8e-15 Identities = 39/96 (40%), Positives = 46/96 (47%), Gaps = 19/96 (19%) Query: 36 PGMPGLPGAPGKDGYDG-------------------LPGPKGEPGIPAIPGIRGPKGQKG 76 PG PG PG+PG G G + GP G+PG+P +PG G G G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 + G G G GP G PG+PG PG G PG GE G Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548 Score = 75.1 bits (183), Expect = 5e-14 Identities = 44/112 (39%), Positives = 52/112 (46%), Gaps = 26/112 (23%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYD-------------GLPGPKGEPGIPAIPGIRGPKG 73 Q G G PG PG+ G PG G + G PG GE G P IPG+ G G Sbjct: 260 QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319 Query: 74 QKGEPGLPGHPGKNGPMGPPGMPGV-------------PGPMGIPGEPGEEG 112 GEPG G G+ G GPPG PG+ G +G+PG PGE+G Sbjct: 320 YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKG 371 Score = 60.5 bits (145), Expect = 1e-09 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 17/97 (17%) Query: 2 DVGPSSLP-HLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 60 D GP +P GLK L P Q G G PG PG G P G+DG G KG+P Sbjct: 1374 DAGPPGIPGQPGLKGLPG----PQGPQGLPGPTGPPGDPGRNGLP---GFDGAGGRKGDP 1426 Query: 61 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPG 97 G+P PG R GL G PG +G GPPG PG Sbjct: 1427 GLPGQPGTR---------GLDGPPGPDGLQGPPGPPG 1454 Score = 38.9 bits (89), Expect = 0.004 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 12/47 (25%) Query: 67 GIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 GI+G KG++G PGL GH PG+PG G G PG G+ Sbjct: 42 GIKGEKGERGFPGLEGH------------PGLPGFPGPEGPPGPRGQ 76 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 102 bits (255), Expect = 2e-22 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 12/96 (12%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMG-- 91 G PG+PG+PG G GY GLPG G+PG+ PG+ GP G KG PGLPG PG GP G Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026 Query: 92 ----------PPGMPGVPGPMGIPGEPGEEGRYKQK 117 P G+ G PGP G+PG+PG G QK Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062 Score = 102 bits (255), Expect = 2e-22 Identities = 46/88 (52%), Positives = 54/88 (61%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHP 84 +G G+PG+PG G PG GY G PG KG G P +PG+ G G KG+PGLPG P Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124 Query: 85 GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G GP GP G+ G PG G+PGEPG G Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVG 1152 Score = 101 bits (252), Expect = 5e-22 Identities = 57/112 (50%), Positives = 65/112 (58%), Gaps = 11/112 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G PG+PGLPG PG+DG GLPGPKGEPG G RGP G PGLPG PG GPM Sbjct: 564 GSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP---PGNPGLPGLPGNIGPM 620 Query: 91 GPPGMPGVPGPM------GIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNS 136 GPPG G PGP+ G+ G PG+ G K T+T Q +P P + Sbjct: 621 GPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT-QPGKPGLPGN 670 Score = 100 bits (248), Expect = 2e-21 Identities = 58/120 (48%), Positives = 66/120 (55%), Gaps = 10/120 (8%) Query: 36 PGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP--GLPGHPGKN---GPM 90 PG PGLPG PG+DG GLPG G PG P +PGI G KG+ G P GLPG PG G Sbjct: 662 PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721 Query: 91 GPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGD 150 GPPG PG PG +G+ G PG G K + F + PP P L F L P+GD Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALP----GPPGPPGLPGFKGAL-GPKGD 776 Score = 97.1 bits (240), Expect = 1e-20 Identities = 48/94 (51%), Positives = 53/94 (56%), Gaps = 12/94 (12%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G GI G PGLPG PG G G+PG G PG IPG G KG++G PG PG PG GP Sbjct: 87 GPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPP 146 Query: 91 GPPGMPG------------VPGPMGIPGEPGEEG 112 GPPG+PG +PGP G PG PG G Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180 Score = 96.7 bits (239), Expect = 2e-20 Identities = 45/82 (54%), Positives = 51/82 (62%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G+PG PG PG G+ G G PGPKG PG+P PG+ GP G KG G G PG G Sbjct: 982 GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVE 1041 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 GPPG GVPG G PG PG++G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKG 1063 Score = 95.5 bits (236), Expect = 4e-20 Identities = 48/100 (48%), Positives = 57/100 (57%), Gaps = 17/100 (17%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGP--------------KGEPGIPAIPGIRGPK 72 + + G G PG+PG G G G GLPGP KGEPG+P IPG+ GPK Sbjct: 922 KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 73 GQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G +G PG PG PG + G PG+PG PGP G PG PG+ G Sbjct: 982 GYQGLPGDPGQPGLS---GQPGLPGPPGPKGNPGLPGQPG 1018 Score = 95.5 bits (236), Expect = 4e-20 Identities = 45/90 (50%), Positives = 51/90 (56%), Gaps = 11/90 (12%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGE-----------PGIPAIPGIRGPKGQKGEPGLPG 82 G PG PG PG GK G DG+PGP G+ PG P +PG+ G KG G PG+PG Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 +PG GP G PG G PG G PG PG G Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244 Score = 95.5 bits (236), Expect = 4e-20 Identities = 43/87 (49%), Positives = 52/87 (59%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPG 85 G G G PG G PG+ G+ GLPGP+G PG+P GI+G KG G+PGLPG PG Sbjct: 1241 GSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1300 Query: 86 KNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G GPPG+ G PG G+ G G+ G Sbjct: 1301 LKGDQGPPGLQGNPGRPGLNGMKGDPG 1327 Score = 95.5 bits (236), Expect = 4e-20 Identities = 50/101 (49%), Positives = 57/101 (56%), Gaps = 15/101 (14%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPG------PKGEPGIPAIPGIRGPKGQKGEPGL 80 + N G G PG PG G PG +G GLPG KG PG P +PG+ G KG +G PGL Sbjct: 1251 KGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1310 Query: 81 ---PGHPGKNGPMGPPGMPGVP------GPMGIPGEPGEEG 112 PG PG NG G PG+PGVP GP G+PG G EG Sbjct: 1311 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEG 1351 Score = 94.7 bits (234), Expect = 6e-20 Identities = 48/91 (52%), Positives = 52/91 (57%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP------GHP 84 G G PG+PGLPG PG G GLPG G PG P GI GP G G PG P GHP Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157 Query: 85 GKNGP---MGPPGMPGVPGPMGIPGEPGEEG 112 G+ GP G PG G+PGP G GEPG+ G Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188 Score = 94.4 bits (233), Expect = 8e-20 Identities = 50/96 (52%), Positives = 58/96 (60%), Gaps = 14/96 (14%) Query: 31 GCYGIPGMPGLPGAPGKDGYDG---LPGP------KGEPGIPAIPG-----IRGPKGQKG 76 G GIPG G+PG G DG G LPGP KGEPG+P PG + G KG+KG Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 EPGLPG PG +GP G G+PG PG G+ G+PG G Sbjct: 968 EPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003 Score = 94.4 bits (233), Expect = 8e-20 Identities = 50/102 (49%), Positives = 56/102 (54%), Gaps = 14/102 (13%) Query: 25 RGQANTGCYGIPGMPGLP---------GAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK 75 +G+ +G PG PGLP G PG G GLPGPKGEPG PG++GP G Sbjct: 1181 KGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPP 1240 Query: 76 GEPG--LPGHPGKNGPMGPPGMP---GVPGPMGIPGEPGEEG 112 G PG L G G GP GPPG P G+PGP G PG PG G Sbjct: 1241 GSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGG 1282 Score = 94.4 bits (233), Expect = 8e-20 Identities = 50/111 (45%), Positives = 58/111 (52%), Gaps = 11/111 (9%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPA---IPGIRGPKGQKGEPGLPGH 83 + + G GIPG PGL G PG G GLPGP G PG P +PG G G+KG+PGLPG Sbjct: 1375 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ 1434 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAP 134 PG G GPPG G+ GP G PG F +TR + AP Sbjct: 1435 PGTRGLDGPPGPDGLQGPPGPPG--------TSSVAHGFLITRHSQTTDAP 1477 Score = 94.0 bits (232), Expect = 1e-19 Identities = 50/103 (48%), Positives = 59/103 (57%), Gaps = 7/103 (6%) Query: 17 LLLLLLPLRGQAN--TGCYGI-PGMP----GLPGAPGKDGYDGLPGPKGEPGIPAIPGIR 69 L LL L L GQ CYG PG G+ G G+ G+ GL G G PG P G Sbjct: 12 LFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPP 71 Query: 70 GPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GP+GQKG+ G+PG PG G GPPG+PG PG G+PG PG +G Sbjct: 72 GPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDG 114 Score = 94.0 bits (232), Expect = 1e-19 Identities = 44/79 (55%), Positives = 50/79 (63%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G PG+ G PG PG G +G PGP+G+ G IPG GPKG +G PGLPG PG G G P Sbjct: 51 GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110 Query: 94 GMPGVPGPMGIPGEPGEEG 112 G G PGP GIPG G +G Sbjct: 111 GHDGAPGPQGIPGCNGTKG 129 Score = 92.4 bits (228), Expect = 3e-19 Identities = 48/105 (45%), Positives = 56/105 (53%), Gaps = 24/105 (22%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKN--- 87 G G PG PG PG G+ G+ LPGP G PG+P G GPKG +G PG PG PG+ Sbjct: 734 GLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD 792 Query: 88 ---------------GPMGPPGMPGV-----PGPMGIPGEPGEEG 112 GPMGPPG+PG+ PGP GIPG G+ G Sbjct: 793 GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837 Score = 92.0 bits (227), Expect = 4e-19 Identities = 46/92 (50%), Positives = 52/92 (56%), Gaps = 6/92 (6%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP------GLPGHPGKN 87 G PG PG PG G G G+PG KGEPG + + GPKG G P GLPG G Sbjct: 132 GFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP 191 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQ 119 GP+GPPG PG+ GP G PG PG +G FQ Sbjct: 192 GPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQ 223 Score = 92.0 bits (227), Expect = 4e-19 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 9/88 (10%) Query: 34 GIPGMPGLPGA------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK---GEPGLPGHP 84 G+PG PG PG PG G G PG KG+PG+P PG GP G K G PG PG P Sbjct: 1086 GLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145 Query: 85 GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G+ GP+G G PG PGP G G+PG++G Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDG 1173 Score = 92.0 bits (227), Expect = 4e-19 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 11/93 (11%) Query: 31 GCYGIPGMPGLPGAPGK---DGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH---- 83 G G PG PGLPG PG G+ G PGP GE G P GI GP GQKGEPG PG Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 84 ----PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG +G G G+PG+PG G+PG GE G Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG 1226 Score = 90.9 bits (224), Expect = 9e-19 Identities = 47/105 (44%), Positives = 58/105 (55%), Gaps = 19/105 (18%) Query: 27 QANTGCYGIPGMPGL------PGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGL 80 + N G G+PG+PGL PG G G GL G KG+PG+P +PG G KG G PG Sbjct: 1287 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1346 Query: 81 PGHPGKNGPMGPPGMPGVPGPM-------------GIPGEPGEEG 112 G G+ G +GPPG PG+PGP GIPG+PG +G Sbjct: 1347 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1391 Score = 90.1 bits (222), Expect = 2e-18 Identities = 53/118 (44%), Positives = 60/118 (50%), Gaps = 15/118 (12%) Query: 3 VGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGL--PGPKGEP 60 +GP LP +G++ P G G PG+ G+PG G G GL PGP GE Sbjct: 810 MGPPGLPGIGVQG-------PPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862 Query: 61 GIPAIPGIRGPKGQKGEPGLP------GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G P IPG GP G G PGLP G PG G MG G PG PGP+GIPG G G Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920 Score = 89.4 bits (220), Expect = 3e-18 Identities = 49/97 (50%), Positives = 54/97 (55%), Gaps = 15/97 (15%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGP------KGQKGEPG-- 79 G G+PGMPG GAPG G G G KGE PG P PG++GP G KGEPG Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161 Query: 80 ----LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 LPG G G GPPG+ G+PGP GIPG G G Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Score = 89.0 bits (219), Expect = 3e-18 Identities = 54/135 (40%), Positives = 65/135 (48%), Gaps = 29/135 (21%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGK-------------DGYDGLPGPKGEPGIPAIPGIRG 70 L Q G G G+ G PG PG+ G GLPG +G PG P I G G Sbjct: 220 LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPG 279 Query: 71 P-------KGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFT 123 P KG++GEPG G PGK+G G PG+PG+PG G PGEPG +G QK + Sbjct: 280 PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDT--- 336 Query: 124 VTRQTHQPPAPNSLI 138 PP P L+ Sbjct: 337 ------GPPGPPGLV 345 Score = 89.0 bits (219), Expect = 3e-18 Identities = 44/93 (47%), Positives = 52/93 (55%), Gaps = 11/93 (11%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGI---------RGPKGQKGEPGLP 81 G G PG+PG PG PG G G+ GP G PG+P PG GP G+KG+PG Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172 Query: 82 GHPGKNGPMGPPGMPGV--PGPMGIPGEPGEEG 112 G PG G G PG PG PGP G+PG G++G Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205 Score = 88.6 bits (218), Expect = 5e-18 Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 8/87 (9%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G PG+PG+ G PG LPGPKG PG P PGI+G G G PG G PG G MGPP Sbjct: 147 GPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206 Query: 94 GMPGVPGP--------MGIPGEPGEEG 112 G PG+PGP G GE GE+G Sbjct: 207 GPPGLPGPKGNMGLNFQGPKGEKGEQG 233 Score = 88.6 bits (218), Expect = 5e-18 Identities = 48/99 (48%), Positives = 53/99 (53%), Gaps = 19/99 (19%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLP------------GPKGEPGIPAIPGIRGPKGQKGE 77 TG G PG PGLPG PG G G P GPKG PGIP PG G G KGE Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546 Query: 78 PG----LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG PG G G +G PG PG+P G+PG PG++G Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLP---GLPGTPGQDG 582 Score = 86.7 bits (213), Expect = 2e-17 Identities = 49/108 (45%), Positives = 60/108 (55%), Gaps = 23/108 (21%) Query: 25 RGQAN-TGCYGIPGMPGLPGAPGKDG----------YDGLPGPKGE---PGIPAIPGIRG 70 +GQA TG G+PG+PG PGAPG G + G+ G KGE PG P +PG+ G Sbjct: 517 KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576 Query: 71 PKGQKGEPGLPG---------HPGKNGPMGPPGMPGVPGPMGIPGEPG 109 GQ G PGLPG G+ GP G PG+PG+PG +G G PG Sbjct: 577 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG 624 Score = 86.3 bits (212), Expect = 2e-17 Identities = 41/86 (47%), Positives = 47/86 (54%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 + + G G PG G PG G+ G DG+PGP G GI PG+ G G G PG+PGH G Sbjct: 56 EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGA 115 Query: 87 NGPMGPPGMPGVPGPMGIPGEPGEEG 112 GP G PG G G G PG PG G Sbjct: 116 PGPQGIPGCNGTKGERGFPGSPGFPG 141 Score = 85.9 bits (211), Expect = 3e-17 Identities = 46/102 (45%), Positives = 53/102 (51%), Gaps = 20/102 (19%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---------------PGIPAIPGIRGPKGQK 75 G G G PG PG PGK G G PG KGE PG +PG++G G + Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 76 GEPGLPGHPGKNGPMGPPGMPGVPGPM-----GIPGEPGEEG 112 G+PGLPG G+ G G PG+PG PGPM G GE GE G Sbjct: 929 GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Score = 85.5 bits (210), Expect = 4e-17 Identities = 47/98 (47%), Positives = 56/98 (57%), Gaps = 18/98 (18%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK-------GQKGEPGLPGHPGK 86 GIPG+PG PG PG+ G DG G KG+ G P PG+ P+ G+KG GLPG PG+ Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 87 NGP------MGPPGMPGVP-----GPMGIPGEPGEEGR 113 G GPPG+PG P GP G PG PGE G+ Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQ 407 Score = 85.1 bits (209), Expect = 5e-17 Identities = 44/86 (51%), Positives = 49/86 (56%), Gaps = 9/86 (10%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP---- 89 G PG PGLPG PG G G PG +G PG P G+ G KG G PG+PG PG GP Sbjct: 1288 GNPGQPGLPGLPGLKGDQGPPGLQGNPGRP---GLNGMKGDPGLPGVPGFPGMKGPSGVP 1344 Query: 90 --MGPPGMPGVPGPMGIPGEPGEEGR 113 GP G PG+ GP G PG PG G+ Sbjct: 1345 GSAGPEGEPGLIGPPGPPGLPGPSGQ 1370 Score = 84.3 bits (207), Expect = 9e-17 Identities = 46/98 (46%), Positives = 52/98 (53%), Gaps = 16/98 (16%) Query: 31 GCYGIPGMPG--LPGAPGKDGYDGLPGPKGEPGIPAI---------PGIRGPKGQ----- 74 G G PG+PG LPG PG G+ G+PGP G PG P PG GPKG+ Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG PG PG G +GP G G PGP G PG G +G Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG 793 Score = 83.6 bits (205), Expect = 1e-16 Identities = 53/128 (41%), Positives = 62/128 (48%), Gaps = 19/128 (14%) Query: 2 DVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP----- 56 D GP P GL + + + + N G G+PG G G PG G GLPGP Sbjct: 335 DTGPPGPP--GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV 392 Query: 57 KGEPGIPAIPGIRGPKGQKGEPG--LPGHPGKNGPMGPPGMPGVPGPMG----------I 104 G PG P PG RG KG +G PG +PG PG +G G PG+PG PGP G Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 105 PGEPGEEG 112 PG PG G Sbjct: 453 PGPPGPPG 460 Score = 83.6 bits (205), Expect = 1e-16 Identities = 51/138 (36%), Positives = 62/138 (44%), Gaps = 49/138 (35%) Query: 25 RGQANTGCYGIPGMPGL------------------PGAPGKDGYDGLPGPKGE------- 59 +G+ G PG PGL PG PG+ G DGLPGPKG+ Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP 807 Query: 60 -----PGIPAI-----------------PGIRGPKGQKGEPGLPG--HPGKNGPMGPPGM 95 PG+P I PG+ G G+KG+PG PG PG G G PG+ Sbjct: 808 GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867 Query: 96 PGVPGPMGIPGEPGEEGR 113 PG PGP+G PG PG G+ Sbjct: 868 PGAPGPIGPPGSPGLPGK 885 Score = 82.8 bits (203), Expect = 2e-16 Identities = 52/130 (40%), Positives = 58/130 (44%), Gaps = 26/130 (20%) Query: 34 GIPGMPGLPGA------------------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQK 75 G G PGLPG PG G +G PGP G PG P PG+ G KG K Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 76 GEPGLP--GHPGKNGPMGPPGMPGVPGPMGI------PGEPGEEGRYKQKFQSVFTVTRQ 127 G+PG+ G PG GP G PG+PG PG GI PG PG G K Q Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125 Query: 128 THQPPAPNSL 137 T PP P + Sbjct: 1126 TPGPPGPKGI 1135 Score = 82.8 bits (203), Expect = 2e-16 Identities = 42/97 (43%), Positives = 51/97 (52%), Gaps = 15/97 (15%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG---------------QK 75 G G+PG G PG PG G G G G+PG+P +PG++G +G K Sbjct: 1264 GFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1323 Query: 76 GEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G+PGLPG PG G GP G+PG GP G PG G G Sbjct: 1324 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG 1360 Score = 81.6 bits (200), Expect = 6e-16 Identities = 43/102 (42%), Positives = 50/102 (49%), Gaps = 19/102 (18%) Query: 27 QANTGCYGIPGMPGLPGA----------------PGKDGYDGLPGPKGEPGIPAIPGIRG 70 + G G PG PGLPG PG+ G GLPGP+G G +PG G Sbjct: 1350 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTG 1406 Query: 71 PKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 P G G GLPG G G G PG+PG PG G+ G PG +G Sbjct: 1407 PPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1448 Score = 81.3 bits (199), Expect = 7e-16 Identities = 47/99 (47%), Positives = 53/99 (53%), Gaps = 17/99 (17%) Query: 31 GCYGIPGMPGLPGA-----PGKDGYDGLPGPKGEPGIP--AIPGIRGPKGQKGEPGLPGH 83 G G PG+PG PGA PG G+ G G KG+ G P +IPG G GQ G PGLPG Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436 Query: 84 PGKNGP----------MGPPGMPGVPGPMGIPGEPGEEG 112 PG GP GPPG PG PG G+ GE G +G Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKG 475 Score = 81.3 bits (199), Expect = 7e-16 Identities = 40/92 (43%), Positives = 48/92 (52%), Gaps = 13/92 (14%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGE-------------PGIPAIPGIRGPKGQKGEPGL 80 G PG PG PG G G G+ G KG+ PG P +PG+ GP G G PG Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQ 513 Query: 81 PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G G+ G GP G+PG+PG G PG PG +G Sbjct: 514 KGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Score = 81.3 bits (199), Expect = 7e-16 Identities = 48/117 (41%), Positives = 55/117 (47%), Gaps = 27/117 (23%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG--IRGPKGQKGEPGL 80 L GQ + G GIPG PGLPG G+ G+ G PG +G PG P PG + GPKG G G Sbjct: 1200 LSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGP 1259 Query: 81 PGHPGKNGPMGP------------------------PGMPGVPGPMGIPGEPGEEGR 113 PG PG G GP PG+PG+ G G PG G GR Sbjct: 1260 PGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGR 1316 Score = 80.9 bits (198), Expect = 9e-16 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 23/102 (22%) Query: 35 IPGMPGLPGAPGKDGYDGLPGPKG----------EPGIPAIPGIRGPKGQKGEPGLPGHP 84 IPG PGL G PG G G PGP G EPG P PG G KG +GE G+ G Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 85 GK----------NGPMGPPGMPGVPGP---MGIPGEPGEEGR 113 G +GP G PG+PG+PGP +G PG+ GE+G+ Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519 Score = 80.5 bits (197), Expect = 1e-15 Identities = 47/113 (41%), Positives = 58/113 (51%), Gaps = 24/113 (21%) Query: 24 LRGQAN-TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI---------PAIPGIRGPKG 73 L G+A +G G G G+ G PG G G+PG G PG+ P +PG G KG Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 74 QKGEPGLPGHP--------GKNGPMGPPGMPGVPGP------MGIPGEPGEEG 112 KGEPGLPG P G G G PG+PG+PG G+PG+PG+ G Sbjct: 942 SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPG 994 Score = 79.7 bits (195), Expect = 2e-15 Identities = 42/93 (45%), Positives = 48/93 (51%), Gaps = 14/93 (15%) Query: 31 GCYGIPGMPGLPGAPGKD-----------GYDGLPGPKGEPGIPAIPGIRGPKGQKGEPG 79 G +GIPG G PG PG D G G PGP G PG P +P G G G PG Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP---GKAGASGFPG 893 Query: 80 LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G G GP GPPG G+PG G+PG G++G Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDG 926 Score = 77.8 bits (190), Expect = 8e-15 Identities = 39/96 (40%), Positives = 46/96 (47%), Gaps = 19/96 (19%) Query: 36 PGMPGLPGAPGKDGYDG-------------------LPGPKGEPGIPAIPGIRGPKGQKG 76 PG PG PG+PG G G + GP G+PG+P +PG G G G Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 + G G G GP G PG+PG PG G PG GE G Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG 548 Score = 75.1 bits (183), Expect = 5e-14 Identities = 44/112 (39%), Positives = 52/112 (46%), Gaps = 26/112 (23%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYD-------------GLPGPKGEPGIPAIPGIRGPKG 73 Q G G PG PG+ G PG G + G PG GE G P IPG+ G G Sbjct: 260 QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319 Query: 74 QKGEPGLPGHPGKNGPMGPPGMPGV-------------PGPMGIPGEPGEEG 112 GEPG G G+ G GPPG PG+ G +G+PG PGE+G Sbjct: 320 YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKG 371 Score = 60.5 bits (145), Expect = 1e-09 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 17/97 (17%) Query: 2 DVGPSSLP-HLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP 60 D GP +P GLK L P Q G G PG PG G P G+DG G KG+P Sbjct: 1377 DAGPPGIPGQPGLKGLPG----PQGPQGLPGPTGPPGDPGRNGLP---GFDGAGGRKGDP 1429 Query: 61 GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPG 97 G+P PG R GL G PG +G GPPG PG Sbjct: 1430 GLPGQPGTR---------GLDGPPGPDGLQGPPGPPG 1457 Score = 38.9 bits (89), Expect = 0.004 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 12/47 (25%) Query: 67 GIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 GI+G KG++G PGL GH PG+PG G G PG G+ Sbjct: 42 GIKGEKGERGFPGLEGH------------PGLPGFPGPEGPPGPRGQ 76 >gi|119508426 alpha 3 type IX collagen [Homo sapiens] Length = 684 Score = 98.6 bits (244), Expect = 4e-21 Identities = 56/125 (44%), Positives = 66/125 (52%), Gaps = 22/125 (17%) Query: 9 PHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGL------------PGP 56 P LLLLLLL L A G+PG PG PG PGK G DG+ PGP Sbjct: 4 PRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGP 63 Query: 57 KGEP---------GIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGE 107 KG P G+P +PG+ G G+ G PG G PG+ G +GPPG PG+ G G+PG Sbjct: 64 KGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL-GGKGLPGP 122 Query: 108 PGEEG 112 PGE G Sbjct: 123 PGEAG 127 Score = 84.0 bits (206), Expect = 1e-16 Identities = 44/91 (48%), Positives = 51/91 (56%), Gaps = 12/91 (13%) Query: 34 GIPGMPGLPGAPG---------KDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHP 84 G PGMPG G G KDG G PGP G G+P G++GP+G +G PG G P Sbjct: 184 GPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPP 243 Query: 85 GKNGPMG---PPGMPGVPGPMGIPGEPGEEG 112 G GP+G PPG+PG PG G GE G EG Sbjct: 244 GDRGPIGFRGPPGIPGAPGKAGDRGERGPEG 274 Score = 82.8 bits (203), Expect = 2e-16 Identities = 41/79 (51%), Positives = 49/79 (62%), Gaps = 3/79 (3%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G G+PGL G G+ G +G PG KG G+P +PG G KG+KGE G G+ G GP Sbjct: 307 GQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERG---RAGELGEAGPS 363 Query: 94 GMPGVPGPMGIPGEPGEEG 112 G PGVPG G+PGE GE G Sbjct: 364 GEPGVPGDAGMPGERGEAG 382 Score = 82.4 bits (202), Expect = 3e-16 Identities = 43/90 (47%), Positives = 49/90 (54%), Gaps = 9/90 (10%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPG 82 PL + G G G PG+PGAPGK G G GP+G RGPKG G PG G Sbjct: 239 PLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEG---------FRGPKGDLGRPGPKG 289 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG GP G PGMPG G G+PG G++G Sbjct: 290 TPGVAGPSGEPGMPGKDGQNGVPGLDGQKG 319 Score = 81.3 bits (199), Expect = 7e-16 Identities = 46/107 (42%), Positives = 51/107 (47%), Gaps = 21/107 (19%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPG 85 G G G+PG PG G G G GL GP G G+P +PG GP PG PGHPG Sbjct: 110 GPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGP------PGPPGHPG 163 Query: 86 ---------------KNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 GP GPPGMPG GP G GE GE G+ +K Sbjct: 164 VLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEK 210 Score = 80.1 bits (196), Expect = 2e-15 Identities = 44/105 (41%), Positives = 51/105 (48%), Gaps = 15/105 (14%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPG---------------PKGEPGIPAIPG 67 P G G G G+PGLPG PG G G PG P G PG P +PG Sbjct: 131 PPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPG 190 Query: 68 IRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 +GP G KGE G G G+ G GPPG G+PG +G+ G G G Sbjct: 191 FKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRG 235 Score = 80.1 bits (196), Expect = 2e-15 Identities = 43/109 (39%), Positives = 54/109 (49%), Gaps = 27/109 (24%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGL---------------PGPKGEPGIPAIPGIRGPKGQK 75 G G+PG+PG PG PG G+ G+ PGP G PG+P G G KG++ Sbjct: 142 GPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQ 201 Query: 76 GEPGLPGHPGKNGPMGPPGMPG------------VPGPMGIPGEPGEEG 112 GE G G G GP GP G+PG +PGP+G PG+ G G Sbjct: 202 GEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIG 250 Score = 79.7 bits (195), Expect = 2e-15 Identities = 41/81 (50%), Positives = 48/81 (59%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G GI G GLPG G+ G GL GPKGE G G +G +G G G+ G PG GP+ Sbjct: 439 GDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPL 498 Query: 91 GPPGMPGVPGPMGIPGEPGEE 111 G G+PGVPG G PG PG+E Sbjct: 499 GLQGVPGVPGITGKPGVPGKE 519 Score = 78.6 bits (192), Expect = 5e-15 Identities = 46/97 (47%), Positives = 49/97 (50%), Gaps = 16/97 (16%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G G PG PG G GLPGP GE G+ PG G +G G GLPG PG GP Sbjct: 98 GAPGERGSLGPPGPPGLGG-KGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPP 156 Query: 91 GPPGMPGV---------------PGPMGIPGEPGEEG 112 GPPG PGV PGP G PG PG +G Sbjct: 157 GPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKG 193 Score = 78.6 bits (192), Expect = 5e-15 Identities = 46/108 (42%), Positives = 53/108 (49%), Gaps = 21/108 (19%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI---PGIRGPKGQKGEPGLPGH 83 Q G G G PG PG G G GL GP+G G+P PG RGP G +G PG+PG Sbjct: 201 QGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGA 260 Query: 84 PGKNGPMG------------------PPGMPGVPGPMGIPGEPGEEGR 113 PGK G G P G PGV GP G PG PG++G+ Sbjct: 261 PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQ 308 Score = 76.6 bits (187), Expect = 2e-14 Identities = 40/85 (47%), Positives = 46/85 (54%), Gaps = 3/85 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPG---PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKN 87 G G+ G G PG PGKDG +G+PG KGE G PG +GP G G PG G G+ Sbjct: 289 GTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEK 348 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEG 112 G G G G GP G PG PG+ G Sbjct: 349 GERGRAGELGEAGPSGEPGVPGDAG 373 Score = 74.7 bits (182), Expect = 7e-14 Identities = 41/91 (45%), Positives = 49/91 (53%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI---PAIPGIRGPKGQKGEPGLPGHPGKN 87 G G+PG+PG G+ G+ G G G GE G P +PG G G++GE G G G Sbjct: 331 GPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGAL 390 Query: 88 GPMGPPGMPGV------PGPMGIPGEPGEEG 112 GP GPPG PGV G MG PG PG +G Sbjct: 391 GPQGPPGAPGVRGFQGQKGSMGDPGLPGPQG 421 Score = 74.7 bits (182), Expect = 7e-14 Identities = 36/82 (43%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Query: 34 GIPGMPGLPGAPGKDGYDGLPG---PKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G+PG G+PG G+ G+ G G P+G PG P + G +G KG G+PGLPG G G + Sbjct: 367 GVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDV 426 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 G G G GP G G G +G Sbjct: 427 GDRGPGGAAGPKGDQGIAGSDG 448 Score = 73.2 bits (178), Expect = 2e-13 Identities = 41/89 (46%), Positives = 48/89 (53%), Gaps = 2/89 (2%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH 83 LRG + G G G G G G G DGLPG KGE G + G +G G +GE G G Sbjct: 422 LRG--DVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGT 479 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G NG G G+PG PGP+G+ G PG G Sbjct: 480 QGPNGTSGVQGVPGPPGPLGLQGVPGVPG 508 Score = 71.2 bits (173), Expect = 7e-13 Identities = 36/82 (43%), Positives = 45/82 (54%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G+ G+PG G PG G G GP G PG P G RG +G +G G G G+ GP Sbjct: 229 GPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPK 288 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 G PG+ G G G+PG+ G+ G Sbjct: 289 GTPGVAGPSGEPGMPGKDGQNG 310 Score = 71.2 bits (173), Expect = 7e-13 Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 13/101 (12%) Query: 25 RGQA-NTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIR------------GP 71 RG+A + G G G G PGAPG G+ G G G+PG+P G+R GP Sbjct: 378 RGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGP 437 Query: 72 KGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 KG +G G G PG G +GP G+ G G G GE G +G Sbjct: 438 KGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG 478 Score = 68.9 bits (167), Expect = 4e-12 Identities = 43/102 (42%), Positives = 48/102 (47%), Gaps = 13/102 (12%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIP------AIPGIRGPKGQKGE 77 LR G G PG G PG PG G G PG +G PG PG RG +G +G+ Sbjct: 544 LRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGD 603 Query: 78 -----PGLPGHPGKNGPMGPPGMPGV--PGPMGIPGEPGEEG 112 GL G G GP GP G+PG G G PGEPG G Sbjct: 604 KGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPG 645 Score = 65.9 bits (159), Expect = 3e-11 Identities = 40/95 (42%), Positives = 44/95 (46%), Gaps = 16/95 (16%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPG--LPGHPGKNGPMG 91 G PG PG G PG G G GP GE G P G +G +G KG G L G G GP G Sbjct: 563 GPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQG 622 Query: 92 P--------------PGMPGVPGPMGIPGEPGEEG 112 P PG PG PG G+PG G +G Sbjct: 623 PQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQG 657 Score = 65.1 bits (157), Expect = 5e-11 Identities = 38/117 (32%), Positives = 47/117 (40%), Gaps = 31/117 (26%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPG------- 79 + +G G G G G G G G+PGP G G+ +PG+ G G+ G PG Sbjct: 465 KGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQR 524 Query: 80 ------------------------LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG G+ GP GPPG PG PG +G PG G G Sbjct: 525 IRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPG 581 Score = 63.9 bits (154), Expect = 1e-10 Identities = 40/124 (32%), Positives = 47/124 (37%), Gaps = 34/124 (27%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIP---------------- 66 P Q G G+ G+PG PG G G G+PG G+PG+P Sbjct: 476 PKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISE 535 Query: 67 ------------------GIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEP 108 G GP G G PG PG G G GPPG G G +G PG Sbjct: 536 QIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPR 595 Query: 109 GEEG 112 G +G Sbjct: 596 GNQG 599 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/92 (41%), Positives = 45/92 (48%), Gaps = 13/92 (14%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI-----PAIPGIRGPKGQKGEPGLPGHPG 85 G G PG G PG G G G PGP+G G A G+ GP+G +G G G PG Sbjct: 569 GSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPG 628 Query: 86 KN--------GPMGPPGMPGVPGPMGIPGEPG 109 + G GPPG PG+PG +G G PG Sbjct: 629 TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660 Score = 50.8 bits (120), Expect = 1e-06 Identities = 30/68 (44%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G G GA G DG +G GP+G G+P G G GEPG PG PG G + Sbjct: 596 GNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSK-DGQDGAPGEPGPPGDPGLPGAI 653 Query: 91 GPPGMPGV 98 G G PG+ Sbjct: 654 GAQGTPGI 661 Score = 34.3 bits (77), Expect = 0.10 Identities = 17/38 (44%), Positives = 19/38 (50%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI 62 +G T G G PG PG PG G G G +G PGI Sbjct: 624 QGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGI 661 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 95.9 bits (237), Expect = 3e-20 Identities = 47/93 (50%), Positives = 58/93 (62%), Gaps = 9/93 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI---PAIPGIRGPKGQKGEPGLPGHPGKN 87 G G PG PG+PG G+ G G PGPKG+PGI P PG+ GPKG G GLPG PG+ Sbjct: 966 GSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEK 1025 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQS 120 G+PG+PGP G PG PG++G +K Q+ Sbjct: 1026 ------GVPGIPGPQGSPGLPGDKGAKGEKGQA 1052 Score = 93.2 bits (230), Expect = 2e-19 Identities = 49/99 (49%), Positives = 57/99 (57%), Gaps = 10/99 (10%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK------GQKG 76 P GQ G G PG+ G G PG G D +PGPKG+ G +PGI G GQ+G Sbjct: 809 PPGGQGPPGLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLPGITGQSGLPGLPGQQG 867 Query: 77 EPGLPGHPGKNGP---MGPPGMPGVPGPMGIPGEPGEEG 112 PG+PG PG G MG PG PG PGP+G PG PGE+G Sbjct: 868 APGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKG 906 Score = 92.4 bits (228), Expect = 3e-19 Identities = 46/90 (51%), Positives = 53/90 (58%), Gaps = 3/90 (3%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 + + G G+PG PGL G+PG GY G PG GE G +PG+ G G KGE GLPG PG Sbjct: 1084 KGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGP 1143 Query: 87 NGP---MGPPGMPGVPGPMGIPGEPGEEGR 113 GP G PG G+PG G GEPG GR Sbjct: 1144 TGPAGQKGEPGSDGIPGSAGEKGEPGLPGR 1173 Score = 91.7 bits (226), Expect = 5e-19 Identities = 52/129 (40%), Positives = 62/129 (48%), Gaps = 40/129 (31%) Query: 31 GCYGIPGMPGLPGAPGKDGYDG---------------------LPGPKGEPGIPAIPGIR 69 G G PG PGLPG PG+DG G LPG G PG P +PG++ Sbjct: 97 GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156 Query: 70 GP-------------KGQKGEPGLPGHPGK------NGPMGPPGMPGVPGPMGIPGEPGE 110 G KG++G PG+PG PG GP+GPPG G PGP G PG PGE Sbjct: 157 GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGE 216 Query: 111 EGRYKQKFQ 119 +G+ FQ Sbjct: 217 KGQMGLSFQ 225 Score = 90.9 bits (224), Expect = 9e-19 Identities = 46/99 (46%), Positives = 53/99 (53%), Gaps = 11/99 (11%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG---IRGPKGQKGEPGLP 81 +G+ G PG PG G G G G PG G PGIP G GP G +G+PGLP Sbjct: 1165 KGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLP 1224 Query: 82 GHP--------GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G P G GP G PG+PG+PGPMG PG PG +G Sbjct: 1225 GSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDG 1263 Score = 90.9 bits (224), Expect = 9e-19 Identities = 49/122 (40%), Positives = 63/122 (51%), Gaps = 6/122 (4%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPG---IPAIPGIRGPKGQKGEPGLPGHP---GKN 87 G+PG+PG G PG G DG+ G KG PG P +PG +G G +G PG+ G P G Sbjct: 1245 GLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSK 1304 Query: 88 GPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNP 147 G MGPPG+PG GP G+PG G +G + PP P +I+ L P Sbjct: 1305 GDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGP 1364 Query: 148 QG 149 +G Sbjct: 1365 EG 1366 Score = 89.7 bits (221), Expect = 2e-18 Identities = 51/120 (42%), Positives = 60/120 (50%), Gaps = 19/120 (15%) Query: 2 DVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDG----LPGPK 57 D GP P G P + G G PG PG PG PG G G LPGP Sbjct: 599 DTGPPGPPGYG----------PAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPP 648 Query: 58 GEPGIPAIPGIRGPKGQKGEPGLPGH---PGKNGPMGPPGM--PGVPGPMGIPGEPGEEG 112 G G+P PG GP+G +G PG PG PG+ G +G PG+ PG PGP G+ G PG+ G Sbjct: 649 GAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMG 708 Score = 89.4 bits (220), Expect = 3e-18 Identities = 51/124 (41%), Positives = 60/124 (48%), Gaps = 16/124 (12%) Query: 27 QANTGCYGIPGMPGLP---GAPGKDGYDGLPGPKGEPGIPAIPGIRGP----------KG 73 Q G G PG PG G PG+DG G+PGP+G PG+ PG +G KG Sbjct: 482 QGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKG 541 Query: 74 QKGEPGLPGHPGKNGPMGPPGM---PGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQ 130 KG+PG PG PG G G PG PG+PGP G PG G +G F +R Sbjct: 542 DKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTG 601 Query: 131 PPAP 134 PP P Sbjct: 602 PPGP 605 Score = 88.6 bits (218), Expect = 5e-18 Identities = 44/89 (49%), Positives = 50/89 (56%), Gaps = 3/89 (3%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 Q G G G PGLPG G G G G G PG+P IPG GP G G PG G G+ Sbjct: 72 QGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGE 131 Query: 87 NGPMGPPGMPGV---PGPMGIPGEPGEEG 112 GP+GPPG+PG PGP G+PG G+ G Sbjct: 132 RGPLGPPGLPGFAGNPGPPGLPGMKGDPG 160 Score = 87.8 bits (216), Expect = 8e-18 Identities = 52/117 (44%), Positives = 63/117 (53%), Gaps = 27/117 (23%) Query: 22 LPLRG-QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGP------KGQ 74 L L+G + + G G PGM G G+PG+DG+ GLPGPKG PG + G RGP G Sbjct: 537 LRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGS 596 Query: 75 KGEPGLPGHPGKNGPMGP------------PGMPGVPGPMG-------IPGEPGEEG 112 +G+ G PG PG GP GP PG PG+PGP G +PG PG EG Sbjct: 597 RGDTGPPGPPG-YGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEG 652 Score = 87.8 bits (216), Expect = 8e-18 Identities = 45/115 (39%), Positives = 57/115 (49%), Gaps = 29/115 (25%) Query: 27 QANTGCYGIPGMP------------GLPGAPGKDGYDGLPGPKGEPGIP----------- 63 + + G G PG P GLPG PG+ G G+PGP+G PG+P Sbjct: 992 KGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQ 1051 Query: 64 ------AIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 IPG+RG KG +G G PG PG+ G G G+PG+PG G+ G PG G Sbjct: 1052 AGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVG 1106 Score = 87.8 bits (216), Expect = 8e-18 Identities = 42/82 (51%), Positives = 48/82 (58%), Gaps = 3/82 (3%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G PG+PG G PG G GLPGPKG+ G+ + GI GP G G G PG G+ GP GP Sbjct: 1357 GEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPT 1416 Query: 94 ---GMPGVPGPMGIPGEPGEEG 112 G PG PGP G+PG G G Sbjct: 1417 GPRGFPGPPGPDGLPGSMGPPG 1438 Score = 87.4 bits (215), Expect = 1e-17 Identities = 43/82 (52%), Positives = 50/82 (60%), Gaps = 1/82 (1%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G+PG PG+ G G+ G GLPG KG PG+P IPG G KG G PG+PG G GP Sbjct: 717 GFNGLPGNPGVQGQKGEPGV-GLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPP 775 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 G G+ G PGP G+PG G G Sbjct: 776 GLQGIRGEPGPPGLPGSVGSPG 797 Score = 87.4 bits (215), Expect = 1e-17 Identities = 47/98 (47%), Positives = 53/98 (54%), Gaps = 11/98 (11%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGI---------PAIPGIRGPKGQ 74 LRG+ G GI G PG PG G+ G G+PG G PG+ P PG+ G KG Sbjct: 1062 LRGEK--GDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGD 1119 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 KG PGL G PG G G PG PG GP G GEPG +G Sbjct: 1120 KGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDG 1157 Score = 85.9 bits (211), Expect = 3e-17 Identities = 48/93 (51%), Positives = 51/93 (54%), Gaps = 14/93 (15%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGI---RGPKGQKGEPGLPGHPGKNGPM 90 G PG PG PG PG G G G KGE G P PGI GP G+KGE G PG PG G Sbjct: 299 GSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEP 358 Query: 91 GP---PGMPGVPGPMGI--------PGEPGEEG 112 GP PG+PG PGP G+ PG PGE G Sbjct: 359 GPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERG 391 Score = 85.9 bits (211), Expect = 3e-17 Identities = 47/90 (52%), Positives = 52/90 (57%), Gaps = 9/90 (10%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIP------AIPGIRGPKGQKGEP--GLPG 82 G G PG+ G PG PG G DGLPG G PG P +PG G +GQKGEP GLPG Sbjct: 682 GAVGQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPG 740 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G G G PG PG G +G+PG PGE G Sbjct: 741 LKGLPGLPGIPGTPGEKGSIGVPGVPGEHG 770 Score = 85.5 bits (210), Expect = 4e-17 Identities = 45/102 (44%), Positives = 58/102 (56%), Gaps = 13/102 (12%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK------GQKG 76 ++GQ G G+ G+ G PG G +G G PG KG+ G P +PG +G + G G Sbjct: 44 VKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPG 103 Query: 77 EPGLPGHPGKNGPMGPPGMPGV------PGPMGIPGEPGEEG 112 PGLPG PG++GP GPPG+PG GP+G PG PG G Sbjct: 104 NPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAG 145 Score = 85.1 bits (209), Expect = 5e-17 Identities = 42/90 (46%), Positives = 46/90 (51%), Gaps = 11/90 (12%) Query: 34 GIPGMPGLP-----------GAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPG 82 G PG PGL G PG G GLPG G+ G P IPG G KG+ G G PG Sbjct: 829 GFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPG 888 Query: 83 HPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG GP+G PG+PG G G PG G G Sbjct: 889 QPGSPGPVGAPGLPGEKGDHGFPGSSGPRG 918 Score = 85.1 bits (209), Expect = 5e-17 Identities = 42/89 (47%), Positives = 49/89 (55%), Gaps = 6/89 (6%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH--- 83 Q G G G+PGLPG G G G PG KGE G+ PG G G G PGLPG Sbjct: 848 QGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGD 907 Query: 84 ---PGKNGPMGPPGMPGVPGPMGIPGEPG 109 PG +GP G PG+ G G +G+PG+PG Sbjct: 908 HGFPGSSGPRGDPGLKGDKGDVGLPGKPG 936 Score = 84.7 bits (208), Expect = 7e-17 Identities = 47/103 (45%), Positives = 54/103 (52%), Gaps = 15/103 (14%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDG---YDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP 81 +G G G PG PG G PGKDG G PG GEPG P + G +GP+G+KGE G P Sbjct: 269 QGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPP 328 Query: 82 GHP------------GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G P G+ G G PG G PGP G PG PG+ G Sbjct: 329 GPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPG 371 Score = 84.7 bits (208), Expect = 7e-17 Identities = 42/89 (47%), Positives = 51/89 (57%), Gaps = 7/89 (7%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGL--PGPKGEPGIPAIPGIRGPKGQKGEPGLPGH----- 83 G G PG PGLPG+ G G G+ PG +G PG PG+ GP G KGE G PG Sbjct: 779 GIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDM 838 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG G G G+PG+ G G+PG PG++G Sbjct: 839 PGPKGDKGAQGLPGITGQSGLPGLPGQQG 867 Score = 83.6 bits (205), Expect = 1e-16 Identities = 49/116 (42%), Positives = 56/116 (48%), Gaps = 30/116 (25%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPA--------IPGIRGPKGQKGEPG--LPGH 83 G PG PG G PG G+ GLPG G PG+P PG RG KG +G PG LPG Sbjct: 347 GYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGP 406 Query: 84 PGKNGPMGPPGMPGVPG--------------------PMGIPGEPGEEGRYKQKFQ 119 G++G GPPG PG PG P GIPG+PG G +K Q Sbjct: 407 SGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQ 462 Score = 83.6 bits (205), Expect = 1e-16 Identities = 45/96 (46%), Positives = 54/96 (56%), Gaps = 6/96 (6%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGL--PGPKGEPGIPAIPGIRGPKGQKGEPG---LP 81 Q + G G PG PGLPG G G G+ PGP G G+ +PG GP G G PG LP Sbjct: 663 QGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLP 722 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 G+PG G G PG+ G+PG G+PG PG G +K Sbjct: 723 GNPGVQGQKGEPGV-GLPGLKGLPGLPGIPGTPGEK 757 Score = 83.6 bits (205), Expect = 1e-16 Identities = 49/130 (37%), Positives = 54/130 (41%), Gaps = 44/130 (33%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGY---DGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH 83 + + G G PG PGLPG G G DG+PG KGE G+P PG GP GQKGEPG G Sbjct: 1099 KGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGI 1158 Query: 84 PGKNGPMGPPGMPG-----------------------------------------VPGPM 102 PG G G PG+PG PGP Sbjct: 1159 PGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQ 1218 Query: 103 GIPGEPGEEG 112 G PG PG G Sbjct: 1219 GQPGLPGSPG 1228 Score = 82.0 bits (201), Expect = 4e-16 Identities = 47/102 (46%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGL---- 80 +GQA GIPG+ G G G G+ G PG KGE G IPG+ G G KG PG Sbjct: 1049 KGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYP 1108 Query: 81 --PGHPGKNGPMGPPGM---PGVPGPMGIPGEPGEEGRYKQK 117 PG PG+ G G PG+ PGV G G+PG PG G QK Sbjct: 1109 GSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150 Score = 81.6 bits (200), Expect = 6e-16 Identities = 48/115 (41%), Positives = 59/115 (51%), Gaps = 13/115 (11%) Query: 11 LGLKLLLLLLLLPL---------RGQANTGCYGIP----GMPGLPGAPGKDGYDGLPGPK 57 +G +L + LLLLP R A GC G G+ G G+ G GL G Sbjct: 1 MGPRLSVWLLLLPAALLLHEEHSRAAAKGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVI 60 Query: 58 GEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG+ G +GP GQKG+ G PG PG G GPPG G PG G+PG PG++G Sbjct: 61 GFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDG 115 Score = 81.6 bits (200), Expect = 6e-16 Identities = 47/117 (40%), Positives = 57/117 (48%), Gaps = 10/117 (8%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG----------IRGPKGQKGEPGL 80 G G G+PGL G G G G+PG KG PG P PG + GP+G G GL Sbjct: 1314 GFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGL 1373 Query: 81 PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSL 137 G PG G G G+ G+PGP GIPG G G+ + + T R PP P+ L Sbjct: 1374 QGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL 1430 Score = 81.3 bits (199), Expect = 7e-16 Identities = 47/104 (45%), Positives = 52/104 (50%), Gaps = 22/104 (21%) Query: 31 GCYGIPGMPGL--------PGAPGKDGYDGLPGPKGEPGIPAIPGIR--GPKGQKGEPGL 80 G G PG+PG+ PG G G G PG KGE G P PG+ GPKG KG GL Sbjct: 791 GSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGL 850 Query: 81 PGH------PGKNGPMGPPGMPGVPGP------MGIPGEPGEEG 112 PG PG G G PG+PG PG MG PG+PG G Sbjct: 851 PGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPG 894 Score = 80.9 bits (198), Expect = 9e-16 Identities = 47/105 (44%), Positives = 53/105 (50%), Gaps = 15/105 (14%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEP-----GIPAIPGIRGPKGQKGE 77 PL + G G PG G PG G G G PGP G P G P PG RG KG +G Sbjct: 339 PLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGF 398 Query: 78 PG--LPGHPGKNGPMGPPGMPGVPGPMGI--------PGEPGEEG 112 PG LPG G++G GPPG PG PG G PG PG++G Sbjct: 399 PGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQG 443 Score = 80.5 bits (197), Expect = 1e-15 Identities = 41/89 (46%), Positives = 51/89 (57%), Gaps = 1/89 (1%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGH 83 ++GQ G+PG+ GLPG PG G G G G PG+P G GP G +G G PG Sbjct: 727 VQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGP 786 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG G +G PG+PG+ GP G G PG +G Sbjct: 787 PGLPGSVGSPGVPGI-GPPGARGPPGGQG 814 Score = 79.0 bits (193), Expect = 4e-15 Identities = 44/104 (42%), Positives = 53/104 (50%), Gaps = 18/104 (17%) Query: 27 QANTGCYGIPGMPG---------LPGAPGKDGYDGLPGP---KGEPGIPAIPGIRGPKGQ 74 + + G G+PG PG + G G G G GP KG G P PG+ G GQ Sbjct: 923 KGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQ 982 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGP------MGIPGEPGEEG 112 G+PG PG G G G PG PG+PGP MG+PG PGE+G Sbjct: 983 AGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKG 1026 Score = 77.4 bits (189), Expect = 1e-14 Identities = 45/112 (40%), Positives = 52/112 (46%), Gaps = 30/112 (26%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGP---KGQKGEPGLPGHP--- 84 G G+ G PG PG+PG G GLPG KG+ G P G RG KG KG+ GLPG P Sbjct: 879 GEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSM 938 Query: 85 ------------------------GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G+ G G PG PGVPG G G+PG+ G Sbjct: 939 DKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990 Score = 75.9 bits (185), Expect = 3e-14 Identities = 48/109 (44%), Positives = 52/109 (47%), Gaps = 27/109 (24%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLP--GPKGEPGI------PAIPG-----------IRGP 71 G G PG PG PG PG+ G GL GPKG+ G P +PG +G Sbjct: 200 GFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGE 259 Query: 72 KGQKGEPGL--------PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 KGQKGEPG G PGK GP G PG G G G PG PGE G Sbjct: 260 KGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPG 308 Score = 75.5 bits (184), Expect = 4e-14 Identities = 47/105 (44%), Positives = 53/105 (50%), Gaps = 21/105 (20%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE---------PGIPAIPGIRGPKGQKG 76 GQA G G PG G PG G G GLPGPKG PG +PGI GP+G G Sbjct: 981 GQA--GQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPG 1038 Query: 77 EPGLPGHPGKNGPMGPPGMPGVP---------GPMGIPGEPGEEG 112 PG G G+ G GPPG+ G+P G G PG PGE+G Sbjct: 1039 LPGDKGAKGEKGQAGPPGI-GIPGLRGEKGDQGIAGFPGSPGEKG 1082 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/125 (40%), Positives = 58/125 (46%), Gaps = 18/125 (14%) Query: 4 GPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIP 63 GP LP G+K +L + G G G PG+PG PG PG G G GP G G P Sbjct: 148 GPPGLP--GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPP 205 Query: 64 AIPGIRGPKGQKGEPGL-----PGHPGKNGPMGPPGMPG-----------VPGPMGIPGE 107 PG GP G+KG+ GL G G G GPPG+PG G G GE Sbjct: 206 GPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGE 265 Query: 108 PGEEG 112 PG +G Sbjct: 266 PGFQG 270 Score = 74.3 bits (181), Expect = 9e-14 Identities = 43/112 (38%), Positives = 50/112 (44%), Gaps = 30/112 (26%) Query: 31 GCYGIPGMPG------LPGAPGKDGYDGLPGPKGEPGIPAIPGIR--------------- 69 G G PG+PG PG+ G G GL G KG+ G+P PG Sbjct: 894 GPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQ 953 Query: 70 ---------GPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G KG +G+PG PG PGK+G G PG PG G GI G PG G Sbjct: 954 GEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPG 1005 Score = 73.9 bits (180), Expect = 1e-13 Identities = 45/111 (40%), Positives = 52/111 (46%), Gaps = 28/111 (25%) Query: 27 QANTGCYGIPGMPGLP------GAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGL 80 Q G G PG PG+ G G+ GY G PGP+GEPG PG+ GQ G PGL Sbjct: 319 QGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGL---PGQPGPPGL 375 Query: 81 --------PGHPGKNGPM-----------GPPGMPGVPGPMGIPGEPGEEG 112 PG PG+ G GP G G+PGP G PG PG+ G Sbjct: 376 PVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPG 426 Score = 73.9 bits (180), Expect = 1e-13 Identities = 40/87 (45%), Positives = 44/87 (50%), Gaps = 13/87 (14%) Query: 34 GIPGMPGLPGAPGK-------------DGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGL 80 GIPG PG G G+ DGY G PGP+G PG PG G KG +G PG Sbjct: 446 GIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGR 505 Query: 81 PGHPGKNGPMGPPGMPGVPGPMGIPGE 107 G G GP G PG+ G PG G PGE Sbjct: 506 DGVAGVPGPQGTPGLIGQPGAKGEPGE 532 Score = 72.4 bits (176), Expect = 3e-13 Identities = 48/127 (37%), Positives = 56/127 (44%), Gaps = 42/127 (33%) Query: 30 TGCYGIPGMPGLPGAPGKDGYD--------GLPGPKGEPGIPAIPGIRGP---KGQKGE- 77 +G G+PG PG PG PG+ GY G PG +G PGIP PG G KGQKGE Sbjct: 407 SGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGES 466 Query: 78 ------------------------PGLPGH------PGKNGPMGPPGMPGVPGPMGIPGE 107 PG PG PG++G G PG G PG +G PG Sbjct: 467 CLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGA 526 Query: 108 PGEEGRY 114 GE G + Sbjct: 527 KGEPGEF 533 Score = 72.0 bits (175), Expect = 4e-13 Identities = 38/78 (48%), Positives = 42/78 (53%), Gaps = 6/78 (7%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G+ G+PG G G G G+PGP G IPG G GQKGE G G G G Sbjct: 1369 GLKGLQGLPGPKGQQGVTGLVGIPGPPG------IPGFDGAPGQKGEMGPAGPTGPRGFP 1422 Query: 91 GPPGMPGVPGPMGIPGEP 108 GPPG G+PG MG PG P Sbjct: 1423 GPPGPDGLPGSMGPPGTP 1440 Score = 70.5 bits (171), Expect = 1e-12 Identities = 46/120 (38%), Positives = 55/120 (45%), Gaps = 34/120 (28%) Query: 27 QANTGCYGIPGMPGLPGAP-----------------GKDGYDGLP--GPKGEPGIP---A 64 + + G G+ G PG+PG G+ G+ G+P G KGEPG P Sbjct: 228 KGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRG 287 Query: 65 IPGIRGPKGQKGEPGLPGHP------GKNGPMGPPGMPGVPGPMGIP------GEPGEEG 112 PG G KG+KG PG PG P G+ GP G G G PGP GI GE GE G Sbjct: 288 KPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERG 347 Score = 67.4 bits (163), Expect = 1e-11 Identities = 39/76 (51%), Positives = 42/76 (55%), Gaps = 12/76 (15%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPG 82 P Q TG GIPG PG+P G+DG PG KGE G PA GP G +G PG PG Sbjct: 1379 PKGQQGVTGLVGIPGPPGIP------GFDGAPGQKGEMG-PA-----GPTGPRGFPGPPG 1426 Query: 83 HPGKNGPMGPPGMPGV 98 G G MGPPG P V Sbjct: 1427 PDGLPGSMGPPGTPSV 1442 Score = 34.7 bits (78), Expect = 0.078 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 9/63 (14%) Query: 70 GPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTH 129 G KGQKGE GLPG G + G PG G G G G+ + T+ T Sbjct: 43 GVKGQKGERGLPGLQG---------VIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTR 93 Query: 130 QPP 132 PP Sbjct: 94 GPP 96 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 95.9 bits (237), Expect = 3e-20 Identities = 47/92 (51%), Positives = 56/92 (60%), Gaps = 14/92 (15%) Query: 29 NTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG-----------QKGE 77 NTG YG+ G+PG G+ G+ G+ GLPG G PGIP G++G KG KG+ Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 PGLPG P GP G PG PG PGP+G PG PG Sbjct: 173 PGLPGAP---GPQGLPGPPGFPGPVGPPGPPG 201 Score = 90.1 bits (222), Expect = 2e-18 Identities = 56/145 (38%), Positives = 65/145 (44%), Gaps = 40/145 (27%) Query: 13 LKLLLLLLLLPLRGQANTGCY-------------------GIPGMPGLPGAPGKDGYDGL 53 L L LLL+LL A+ GC G PG PG PG G G +GL Sbjct: 12 LLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGL 71 Query: 54 PGPKGEPGIPAIPGIRGPKGQK---------GEPGLPGHPGKNGP------------MGP 92 PGP+G G P +PG+ G KG + G PGLPG PG GP G Sbjct: 72 PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131 Query: 93 PGMPGVPGPMGIPGEPGEEGRYKQK 117 G PG+PG +G PG PG G QK Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQK 156 Score = 89.4 bits (220), Expect = 3e-18 Identities = 48/102 (47%), Positives = 57/102 (55%), Gaps = 12/102 (11%) Query: 24 LRGQ----ANTGCYGIPGMPGLP--------GAPGKDGYDGLPGPKGEPGIPAIPGIRGP 71 L+GQ TG G PG+PGL G+PG G+ G GP G+ G P PGI GP Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 72 KGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G+ G G+ G PG GP GPPG PG PG G PG PG +G+ Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQ 926 Score = 88.2 bits (217), Expect = 6e-18 Identities = 50/100 (50%), Positives = 54/100 (54%), Gaps = 19/100 (19%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI--PGIRGPKGQKG--------------- 76 G G PG+PG+ GK G GLPGP GEPGIP I PG GPKG +G Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 77 EPGLPGHPGKNGPMGPP--GMPGVPGPMGIPGEPGEEGRY 114 EPGLPG PG G G P MPG PG G PGE G G + Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767 Score = 87.8 bits (216), Expect = 8e-18 Identities = 49/116 (42%), Positives = 59/116 (50%), Gaps = 12/116 (10%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG---IRGPKGQKGEPGLPGHPGKN 87 G G+PG PGL G PG+ G DG+PG G G+P G + G KG +G PG PG PG Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607 Query: 88 GP--------MGPPGMPGVPGPMGIPGEPGEEGRYKQKFQ-SVFTVTRQTHQPPAP 134 GP GP G PG+ G G+PG PG G + + SV T PP P Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Score = 86.3 bits (212), Expect = 2e-17 Identities = 47/106 (44%), Positives = 56/106 (52%), Gaps = 24/106 (22%) Query: 31 GCYGIPGMPGLPGAPGK------DGYDGLPGPKGE----------PGIPAIPGIRGPKGQ 74 G G PG+PG PG+PG G DG+PGP GE PG PG +G KG Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193 Query: 75 KGEPGLPGHPGKNG------PMGPPGMPGVPGPMGIPGE--PGEEG 112 +G PG PG PG+ G P GP G+ G PGP G+PG PG+ G Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/97 (44%), Positives = 53/97 (54%), Gaps = 11/97 (11%) Query: 31 GCYGIPGMPGLPGAPGKDGYDG-----------LPGPKGEPGIPAIPGIRGPKGQKGEPG 79 G +G+PG G PG PG DG G +PGP G PG+P + G++G G++G G Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508 Query: 80 LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQ 116 L G PG G G PG PG PG G PG GE+G Q Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/82 (52%), Positives = 47/82 (57%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G PG PG G G +G PG G PG+P PG G G KG GL G PG GP Sbjct: 1080 GKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 G PG PG PGPMGI G+ G +G Sbjct: 1140 GLPGFPGSPGPMGIRGDQGRDG 1161 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/91 (47%), Positives = 49/91 (53%), Gaps = 12/91 (13%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G G G PG G G GLPGP+G+PG PG++G KG G G G PG GP GPP Sbjct: 1283 GTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Query: 94 G------------MPGVPGPMGIPGEPGEEG 112 G +PG PGP G PGEPG +G Sbjct: 1343 GVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 85.1 bits (209), Expect = 5e-17 Identities = 42/87 (48%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPG 85 G+ G G G+PGL G G+ G G GPKG+PGIP + G G+ G PG+PGH G Sbjct: 807 GRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR-SGFPGETGSPGIPGHQG 865 Query: 86 KNGPMGPPGMPGVPGPMGIPGEPGEEG 112 + GP+G G PG PG +G PGE G G Sbjct: 866 EMGPLGQRGYPGNPGILGPPGEDGVIG 892 Score = 83.6 bits (205), Expect = 1e-16 Identities = 45/107 (42%), Positives = 51/107 (47%), Gaps = 24/107 (22%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI---------------PGIRGPKG-- 73 G G PG PGLPG G G+ G PG KGE G P PG+RG G Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351 Query: 74 -------QKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G PG PG PG G GPPG PG GP G G+PG++G+ Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGK 1398 Score = 83.2 bits (204), Expect = 2e-16 Identities = 41/82 (50%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G G PG+PG G G PGP G+ G I G+ GP G +G PGLPG PG GPM Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPM 1151 Query: 91 ---GPPGMPGVPGPMGIPGEPG 109 G G G+PGP G GE G Sbjct: 1152 GIRGDQGRDGIPGPAGEKGETG 1173 Score = 82.4 bits (202), Expect = 3e-16 Identities = 44/97 (45%), Positives = 52/97 (53%), Gaps = 15/97 (15%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQ------------KGEP 78 G G PG PG PG PG+ G G+PG KG+ G P G +G KG KGEP Sbjct: 898 GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 79 GL---PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GL G+PG+ G G PGMPG+ G G+PG G G Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG 994 Score = 82.0 bits (201), Expect = 4e-16 Identities = 48/117 (41%), Positives = 56/117 (47%), Gaps = 35/117 (29%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGP------------KGQKGEP 78 G G PG+PGL G+ G G GLPG G PG+P PG GP KG++G P Sbjct: 76 GPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFP 135 Query: 79 GLP---GHPG----------KNGP----------MGPPGMPGVPGPMGIPGEPGEEG 112 GLP G+PG K P G PG+PG PGP G+PG PG G Sbjct: 136 GLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPG 192 Score = 82.0 bits (201), Expect = 4e-16 Identities = 48/101 (47%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE--------PGIPAIPGIRGPKGQ 74 P Q G G G PG G PG G GLPG KGE PG P PG RG G+ Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGE 766 Query: 75 KGE------PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 GE PGLPG PG G GP G PG PGP G G PG Sbjct: 767 HGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807 Score = 81.6 bits (200), Expect = 6e-16 Identities = 44/101 (43%), Positives = 47/101 (46%), Gaps = 22/101 (21%) Query: 31 GCYGIPGMPGLPGA----------------------PGKDGYDGLPGPKGEPGIPAIPGI 68 G G+PG PG PGA PG G G PG KG GIP PG+ Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576 Query: 69 RGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 +G G KGE L G G GP G PG PG PGP G G PG Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Score = 81.6 bits (200), Expect = 6e-16 Identities = 51/124 (41%), Positives = 57/124 (45%), Gaps = 34/124 (27%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGK------DGYDGLPGPKGEPGIPAIPGIRGP----- 71 LRGQ G GIPG PG+ G PG G G GP G+PG P PG GP Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 72 ---------KGQKGEPGLPGHPGKNGPMG-------------PPGMPGVPGPMGIPGEPG 109 +G +G PG PG PG+ GP G PPG PG PGP G PG PG Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 110 EEGR 113 G+ Sbjct: 678 SLGK 681 Score = 81.6 bits (200), Expect = 6e-16 Identities = 44/95 (46%), Positives = 52/95 (54%), Gaps = 16/95 (16%) Query: 34 GIPGMPGL--PGAPGKDGYDGLPGPKG---------EPGIPAIPGIRGPKGQ-----KGE 77 G PG+PG+ PG PG G G PG KG EPG+P PG+ G KG+ G Sbjct: 692 GEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGG 751 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG PG PG+ G G G G+PG G+PG PG EG Sbjct: 752 PGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG 786 Score = 80.9 bits (198), Expect = 9e-16 Identities = 49/113 (43%), Positives = 58/113 (51%), Gaps = 26/113 (23%) Query: 26 GQANTGCYGIPGMPGLPGA------PGKD--GYDGLPGPKGEPGIPAIPGIRGP------ 71 G + G G PG PGL G+ PGKD G G PG G PG+P PG GP Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443 Query: 72 -KGQKGEPGLPGH------PGKNGPMGPPGM-----PGVPGPMGIPGEPGEEG 112 KG G+ GLPG+ PG +GP G PG+ P +PGP G+PG PG G Sbjct: 444 RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496 Score = 80.9 bits (198), Expect = 9e-16 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 12/98 (12%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDG-------LPGPKGEPGIPAIPGIRGPKGQKGEPG 79 Q G G G+PG PG PG+ G G +PGP G PG P PG +GP G G G Sbjct: 621 QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680 Query: 80 LPGHPGKNGPMGPPGMPGV-----PGPMGIPGEPGEEG 112 G PG GP G PG+PG+ PGP G G PG +G Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718 Score = 79.3 bits (194), Expect = 3e-15 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 23/106 (21%) Query: 31 GCYGIPGMPG---LPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG----------- 76 G GIPG G +PG+ GK G G PG G PG+P I G++G KG+ G Sbjct: 1009 GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068 Query: 77 ---EPGLPGHPGKNGPMGPPGMPGVPGPMG------IPGEPGEEGR 113 +PGLPG GK G MG PG PG GP G PG PG G+ Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK 1114 Score = 79.0 bits (193), Expect = 4e-15 Identities = 47/115 (40%), Positives = 52/115 (45%), Gaps = 27/115 (23%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP-------KGEP---------GIPAIPGI 68 RG+ G PG PG G+PG G G PGP KG P G P IPG+ Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 69 RGPKGQ-----------KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GPKG+ G PGLPG PG +G G PG G G G PG PG G Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520 Score = 79.0 bits (193), Expect = 4e-15 Identities = 41/95 (43%), Positives = 49/95 (51%), Gaps = 9/95 (9%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGP---------KGEPGIPAIPGIRGPKGQKGE 77 + + G G+ G G PGA G+ G G PGP KGEPG+ G G KG +G Sbjct: 915 RGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGV 974 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+PG G G GP G PG G +G G PGE G Sbjct: 975 PGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Score = 78.6 bits (192), Expect = 5e-15 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 7/90 (7%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP---GHPGK 86 T C IPG PGLPG PG G G+PG +G G+ PG G G G PG P G PG Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536 Query: 87 NGPMG----PPGMPGVPGPMGIPGEPGEEG 112 G G P G GVPG G+ G+PG +G Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566 Score = 78.2 bits (191), Expect = 6e-15 Identities = 40/89 (44%), Positives = 49/89 (55%), Gaps = 3/89 (3%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 + N G G+PG+ GL G PG G G G G G P PG+RG G G G+PG GK Sbjct: 969 KGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGK 1028 Query: 87 NGPMGPP---GMPGVPGPMGIPGEPGEEG 112 G +G P G PG+PG G+ G+ GE G Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057 Score = 77.4 bits (189), Expect = 1e-14 Identities = 50/124 (40%), Positives = 55/124 (44%), Gaps = 35/124 (28%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP---KGEPGIPAI--------------- 65 L G++ G PG PGL G PGKDG G PG KG G P + Sbjct: 278 LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337 Query: 66 PGIRGP---------KGQKGEPGLPGHPGKNGPMGPPGMPGVPGP--------MGIPGEP 108 PG RGP KG +G PG PG G GP GP G PGVPG G PG P Sbjct: 338 PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397 Query: 109 GEEG 112 G +G Sbjct: 398 GLKG 401 Score = 77.4 bits (189), Expect = 1e-14 Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 29/108 (26%) Query: 34 GIPGMPGLPGAPGKDGYDG--LPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMG 91 G+PG+ GL G G+ GY PGP G G P +PG G KG+ G+PG PGH G GP G Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101 Query: 92 PPGMPGVPG---------------------------PMGIPGEPGEEG 112 PG PG PG P G+PG PG G Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Score = 76.6 bits (187), Expect = 2e-14 Identities = 40/98 (40%), Positives = 52/98 (53%), Gaps = 8/98 (8%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK---GQKGEPGL 80 L G +PG PG PG PG+ G G G G PG+P +PG G + G +G+PG Sbjct: 737 LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQ 796 Query: 81 PGHPGKNGP-----MGPPGMPGVPGPMGIPGEPGEEGR 113 PG PG+ GP GP G G+PG G+ G+ G G+ Sbjct: 797 PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834 Score = 76.6 bits (187), Expect = 2e-14 Identities = 41/89 (46%), Positives = 45/89 (50%), Gaps = 12/89 (13%) Query: 36 PGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP------ 89 PG PG G PG G G G G+PG P G GP+G G PG PG PGK GP Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 90 ------MGPPGMPGVPGPMGIPGEPGEEG 112 +GPPG+ G PG G PG PG G Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMG 1152 Score = 75.5 bits (184), Expect = 4e-14 Identities = 50/129 (38%), Positives = 54/129 (41%), Gaps = 46/129 (35%) Query: 30 TGCYGIPGMPGLPGA--PGKDGYDGLPGPKGEPGIPAIPG--------IRGPKGQKGEPG 79 TG G PG PGLPGA PG+ G G PG +G PG P PG I+G KG G PG Sbjct: 1218 TGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277 Query: 80 LPGHPGKNGPMGPPG---------------------MPGV---------------PGPMG 103 G PG G MGPPG PGV PGP+G Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337 Query: 104 IPGEPGEEG 112 G PG G Sbjct: 1338 PKGPPGVRG 1346 Score = 75.1 bits (183), Expect = 5e-14 Identities = 44/100 (44%), Positives = 49/100 (49%), Gaps = 18/100 (18%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGL---------PGPKGEPGIP---AIPGIRGPKGQKGEP 78 G G PG PG+ G PG+DG G+ PGP G PG P PGI G KGQ+G P Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930 Query: 79 GLPGHPGKNGPMGPP------GMPGVPGPMGIPGEPGEEG 112 G G G G GP G G PG G G PGE+G Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/137 (36%), Positives = 55/137 (40%), Gaps = 43/137 (31%) Query: 19 LLLLPLRGQANTGCYGIPGMPGLPGAP---------------GKDGYDGLPGPKGEPG-- 61 LL P + N G G G G PG P G G +G PGP G PG Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 62 IPAIPGIRGPKGQKGEPGLP--------------------GHPGKNGP------MGPPGM 95 IP G RGP G +G PG P GHPG GP MGPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 96 PGVPGPMGIPGEPGEEG 112 G PG G+PG G+ G Sbjct: 1294 LGAPGTPGLPGPRGDPG 1310 Score = 74.7 bits (182), Expect = 7e-14 Identities = 45/106 (42%), Positives = 48/106 (45%), Gaps = 19/106 (17%) Query: 27 QANTGCYGIPGMPGLPGAPGK---------DGYDGLPGPKGEPG--IPAIPGIRGPKGQK 75 Q G G PG PGLPG G G +G PGP G PG IP G RGP G + Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSR 1247 Query: 76 GEPGLPGHPGK--------NGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G PG PG PG G G G PG GP G G+ G GR Sbjct: 1248 GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Score = 74.3 bits (181), Expect = 9e-14 Identities = 45/104 (43%), Positives = 52/104 (50%), Gaps = 14/104 (13%) Query: 23 PLRGQANTGCYGIPGMPGLPGAP-----GKDGYDGLPGPKGEPGIPA--IPGIRGPKGQK 75 P + G G PG+PG PG+ G G+ GL G KGE G P G G G Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCA 423 Query: 76 GEPGLPGHPGKNGP-------MGPPGMPGVPGPMGIPGEPGEEG 112 G PGLPG PG GP GPPG G+PG +G PG PG +G Sbjct: 424 GSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDG 467 Score = 73.9 bits (180), Expect = 1e-13 Identities = 50/134 (37%), Positives = 57/134 (42%), Gaps = 17/134 (12%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPG--------PKGEPGIPAIPGIRGPKGQKGEP 78 Q G G G PG+PGA G G G P KG+PG+P P G +G P Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP------GPQGLP 185 Query: 79 GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLI 138 G PG PG GP GPPG G PG MG G G G + V T P P ++I Sbjct: 186 GPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVI 245 Query: 139 RFNAVLTNPQGDYD 152 LT P D Sbjct: 246 ---VTLTGPDNRTD 256 Score = 73.9 bits (180), Expect = 1e-13 Identities = 39/91 (42%), Positives = 46/91 (50%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG---------EPGLP 81 G G PG+ G G PG+ G G+PG G G+ +PG GP G +G EPGL Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG G MG PG G G +G PG G G Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Score = 73.9 bits (180), Expect = 1e-13 Identities = 41/94 (43%), Positives = 52/94 (55%), Gaps = 8/94 (8%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE------PGIPAIPGIRGPKGQKGEPGL 80 + + G G PG PGL G PG G G+PG KG+ PG PG+ G G +G+ G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055 Query: 81 PGHP--GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+ + GP GP G PG+PG MG GE G+ G Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089 Score = 73.6 bits (179), Expect = 2e-13 Identities = 44/113 (38%), Positives = 54/113 (47%), Gaps = 26/113 (23%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGPKGQKGEPGLPGHPGKN 87 G G+PGMPGL G G G G PGP+G+ G P PG+RG G G G+PG GK Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR 1029 Query: 88 GPMG------PPGMPGV-----------------PGPMGIPGEPGEEGRYKQK 117 G +G PG+PG+ PGP G G+PG G +K Sbjct: 1030 GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKK 1082 Score = 73.6 bits (179), Expect = 2e-13 Identities = 42/110 (38%), Positives = 52/110 (47%), Gaps = 19/110 (17%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGL------PGPKGEPGIPAIPGIRGP---KG 73 P + G G PG+PG PG G G+ G+ PG +G PG+P PG GP +G Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155 Query: 74 QKGEPGLPGHPGKN----------GPMGPPGMPGVPGPMGIPGEPGEEGR 113 +G G+PG G+ GP G PG G G G PG PG GR Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205 Score = 72.0 bits (175), Expect = 4e-13 Identities = 44/99 (44%), Positives = 48/99 (48%), Gaps = 17/99 (17%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPG-----IPAIPGIRGPKGQKGEPGLPGH-- 83 G G PG PG GA G G G PG G PG + PG G KG KGE G PG Sbjct: 354 GDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA 413 Query: 84 ---PGKNGPMGPPGMPGVPGPMGIPGE-------PGEEG 112 PG G G PG+PG PGP G PG+ PG+ G Sbjct: 414 MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Score = 71.2 bits (173), Expect = 7e-13 Identities = 38/83 (45%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNG---PM 90 G+ G G PG G G G+PG KG G+P G GP+G G G PG PG G M Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017 Query: 91 GPPGMPGVPGPMGIPGEPGEEGR 113 G GMPG G G G PG GR Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGR 1040 Score = 70.5 bits (171), Expect = 1e-12 Identities = 48/130 (36%), Positives = 53/130 (40%), Gaps = 39/130 (30%) Query: 22 LPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE---- 77 + L + + G G PG GLPG PG G G PGP G G P G RGPKG GE Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 78 -PGLPGHPGKNGPMGPPGM--------------------------PGVPGPMGIPGE--- 107 G G G GP GPPG PG PGP G+PGE Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284 Query: 108 -----PGEEG 112 PG+ G Sbjct: 285 SEKGAPGDPG 294 Score = 70.1 bits (170), Expect = 2e-12 Identities = 40/89 (44%), Positives = 44/89 (49%), Gaps = 12/89 (13%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI------PGIRGPKGQKGEPGLPGH 83 TG GIPG G G G+ GY G PG G PG + PG GP G G PG PG Sbjct: 855 TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG+PGV G G PG GE+G Sbjct: 915 ------RGSPGIPGVKGQRGTPGAKGEQG 937 Score = 68.6 bits (166), Expect = 5e-12 Identities = 43/103 (41%), Positives = 48/103 (46%), Gaps = 16/103 (15%) Query: 31 GCYGIPGMPGLPGA-----PGKDGYDGLPGPKGEPGIPAIPGIRGP-----------KGQ 74 G G+ G PG PG G D L G KG+ G PG GP KG Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 G+PGL G PGK+G G PG GV G G PG GE+G QK Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQK 332 Score = 63.5 bits (153), Expect = 2e-10 Identities = 36/84 (42%), Positives = 42/84 (50%), Gaps = 9/84 (10%) Query: 23 PLRGQANTGCYGIPG------MPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG 76 P+ + G G PG +PG PG PG G PG +GEPG P PG GP G +G Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE---PGMQGEPGPPGPPGNLGPCGPRG 1391 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPG 100 +PG G PG GP G G G G Sbjct: 1392 KPGKDGKPGTPGPAGEKGNKGSKG 1415 Score = 61.6 bits (148), Expect = 6e-10 Identities = 41/110 (37%), Positives = 47/110 (42%), Gaps = 21/110 (19%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGKD--GYDGLPGPKGE------PGIPAIPGIRGPKGQ 74 L+G+ + G G PG PG G PG+ G PG G G+P PG G KG Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPM------------GIPGEPGEEG 112 +G PGL G G G G G PG GP G PG PG G Sbjct: 317 RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRG 366 Score = 61.2 bits (147), Expect = 8e-10 Identities = 39/93 (41%), Positives = 43/93 (46%), Gaps = 21/93 (22%) Query: 31 GCYGIPGMPGLPGA------PGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHP 84 G G PG+ G PG PG G PG GEPG+ +GEPG PG P Sbjct: 1337 GPKGPPGVRGDPGTLKIISLPGSPGP---PGTPGEPGM------------QGEPGPPGPP 1381 Query: 85 GKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 G GP GP G PG G G PG GE+G K Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414 Score = 32.3 bits (72), Expect = 0.39 Identities = 21/50 (42%), Positives = 22/50 (44%), Gaps = 15/50 (30%) Query: 29 NTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP 78 N G G G PG G P G PGP GE +G KG KGEP Sbjct: 1383 NLGPCGPRGKPGKDGKP------GTPGPAGE---------KGNKGSKGEP 1417 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 95.9 bits (237), Expect = 3e-20 Identities = 47/92 (51%), Positives = 56/92 (60%), Gaps = 14/92 (15%) Query: 29 NTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG-----------QKGE 77 NTG YG+ G+PG G+ G+ G+ GLPG G PGIP G++G KG KG+ Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 PGLPG P GP G PG PG PGP+G PG PG Sbjct: 173 PGLPGAP---GPQGLPGPPGFPGPVGPPGPPG 201 Score = 90.1 bits (222), Expect = 2e-18 Identities = 56/145 (38%), Positives = 65/145 (44%), Gaps = 40/145 (27%) Query: 13 LKLLLLLLLLPLRGQANTGCY-------------------GIPGMPGLPGAPGKDGYDGL 53 L L LLL+LL A+ GC G PG PG PG G G +GL Sbjct: 12 LLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGL 71 Query: 54 PGPKGEPGIPAIPGIRGPKGQK---------GEPGLPGHPGKNGP------------MGP 92 PGP+G G P +PG+ G KG + G PGLPG PG GP G Sbjct: 72 PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131 Query: 93 PGMPGVPGPMGIPGEPGEEGRYKQK 117 G PG+PG +G PG PG G QK Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQK 156 Score = 89.4 bits (220), Expect = 3e-18 Identities = 48/102 (47%), Positives = 57/102 (55%), Gaps = 12/102 (11%) Query: 24 LRGQ----ANTGCYGIPGMPGLP--------GAPGKDGYDGLPGPKGEPGIPAIPGIRGP 71 L+GQ TG G PG+PGL G+PG G+ G GP G+ G P PGI GP Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 72 KGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G+ G G+ G PG GP GPPG PG PG G PG PG +G+ Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQ 926 Score = 88.2 bits (217), Expect = 6e-18 Identities = 50/100 (50%), Positives = 54/100 (54%), Gaps = 19/100 (19%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI--PGIRGPKGQKG--------------- 76 G G PG+PG+ GK G GLPGP GEPGIP I PG GPKG +G Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 77 EPGLPGHPGKNGPMGPP--GMPGVPGPMGIPGEPGEEGRY 114 EPGLPG PG G G P MPG PG G PGE G G + Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767 Score = 87.8 bits (216), Expect = 8e-18 Identities = 49/116 (42%), Positives = 59/116 (50%), Gaps = 12/116 (10%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG---IRGPKGQKGEPGLPGHPGKN 87 G G+PG PGL G PG+ G DG+PG G G+P G + G KG +G PG PG PG Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607 Query: 88 GP--------MGPPGMPGVPGPMGIPGEPGEEGRYKQKFQ-SVFTVTRQTHQPPAP 134 GP GP G PG+ G G+PG PG G + + SV T PP P Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Score = 86.3 bits (212), Expect = 2e-17 Identities = 47/106 (44%), Positives = 56/106 (52%), Gaps = 24/106 (22%) Query: 31 GCYGIPGMPGLPGAPGK------DGYDGLPGPKGE----------PGIPAIPGIRGPKGQ 74 G G PG+PG PG+PG G DG+PGP GE PG PG +G KG Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193 Query: 75 KGEPGLPGHPGKNG------PMGPPGMPGVPGPMGIPGE--PGEEG 112 +G PG PG PG+ G P GP G+ G PGP G+PG PG+ G Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/97 (44%), Positives = 53/97 (54%), Gaps = 11/97 (11%) Query: 31 GCYGIPGMPGLPGAPGKDGYDG-----------LPGPKGEPGIPAIPGIRGPKGQKGEPG 79 G +G+PG G PG PG DG G +PGP G PG+P + G++G G++G G Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508 Query: 80 LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQ 116 L G PG G G PG PG PG G PG GE+G Q Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/82 (52%), Positives = 47/82 (57%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G PG PG G G +G PG G PG+P PG G G KG GL G PG GP Sbjct: 1080 GKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 G PG PG PGPMGI G+ G +G Sbjct: 1140 GLPGFPGSPGPMGIRGDQGRDG 1161 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/91 (47%), Positives = 49/91 (53%), Gaps = 12/91 (13%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G G G PG G G GLPGP+G+PG PG++G KG G G G PG GP GPP Sbjct: 1283 GTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Query: 94 G------------MPGVPGPMGIPGEPGEEG 112 G +PG PGP G PGEPG +G Sbjct: 1343 GVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 85.1 bits (209), Expect = 5e-17 Identities = 42/87 (48%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPG 85 G+ G G G+PGL G G+ G G GPKG+PGIP + G G+ G PG+PGH G Sbjct: 807 GRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR-SGFPGETGSPGIPGHQG 865 Query: 86 KNGPMGPPGMPGVPGPMGIPGEPGEEG 112 + GP+G G PG PG +G PGE G G Sbjct: 866 EMGPLGQRGYPGNPGILGPPGEDGVIG 892 Score = 83.6 bits (205), Expect = 1e-16 Identities = 45/107 (42%), Positives = 51/107 (47%), Gaps = 24/107 (22%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI---------------PGIRGPKG-- 73 G G PG PGLPG G G+ G PG KGE G P PG+RG G Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351 Query: 74 -------QKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G PG PG PG G GPPG PG GP G G+PG++G+ Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGK 1398 Score = 83.2 bits (204), Expect = 2e-16 Identities = 41/82 (50%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G G PG+PG G G PGP G+ G I G+ GP G +G PGLPG PG GPM Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPM 1151 Query: 91 ---GPPGMPGVPGPMGIPGEPG 109 G G G+PGP G GE G Sbjct: 1152 GIRGDQGRDGIPGPAGEKGETG 1173 Score = 82.4 bits (202), Expect = 3e-16 Identities = 44/97 (45%), Positives = 52/97 (53%), Gaps = 15/97 (15%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQ------------KGEP 78 G G PG PG PG PG+ G G+PG KG+ G P G +G KG KGEP Sbjct: 898 GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 79 GL---PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GL G+PG+ G G PGMPG+ G G+PG G G Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG 994 Score = 82.0 bits (201), Expect = 4e-16 Identities = 48/117 (41%), Positives = 56/117 (47%), Gaps = 35/117 (29%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGP------------KGQKGEP 78 G G PG+PGL G+ G G GLPG G PG+P PG GP KG++G P Sbjct: 76 GPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFP 135 Query: 79 GLP---GHPG----------KNGP----------MGPPGMPGVPGPMGIPGEPGEEG 112 GLP G+PG K P G PG+PG PGP G+PG PG G Sbjct: 136 GLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPG 192 Score = 82.0 bits (201), Expect = 4e-16 Identities = 48/101 (47%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE--------PGIPAIPGIRGPKGQ 74 P Q G G G PG G PG G GLPG KGE PG P PG RG G+ Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGE 766 Query: 75 KGE------PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 GE PGLPG PG G GP G PG PGP G G PG Sbjct: 767 HGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807 Score = 81.6 bits (200), Expect = 6e-16 Identities = 44/101 (43%), Positives = 47/101 (46%), Gaps = 22/101 (21%) Query: 31 GCYGIPGMPGLPGA----------------------PGKDGYDGLPGPKGEPGIPAIPGI 68 G G+PG PG PGA PG G G PG KG GIP PG+ Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576 Query: 69 RGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 +G G KGE L G G GP G PG PG PGP G G PG Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Score = 81.6 bits (200), Expect = 6e-16 Identities = 51/124 (41%), Positives = 57/124 (45%), Gaps = 34/124 (27%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGK------DGYDGLPGPKGEPGIPAIPGIRGP----- 71 LRGQ G GIPG PG+ G PG G G GP G+PG P PG GP Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 72 ---------KGQKGEPGLPGHPGKNGPMG-------------PPGMPGVPGPMGIPGEPG 109 +G +G PG PG PG+ GP G PPG PG PGP G PG PG Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 110 EEGR 113 G+ Sbjct: 678 SLGK 681 Score = 81.6 bits (200), Expect = 6e-16 Identities = 44/95 (46%), Positives = 52/95 (54%), Gaps = 16/95 (16%) Query: 34 GIPGMPGL--PGAPGKDGYDGLPGPKG---------EPGIPAIPGIRGPKGQ-----KGE 77 G PG+PG+ PG PG G G PG KG EPG+P PG+ G KG+ G Sbjct: 692 GEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGG 751 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG PG PG+ G G G G+PG G+PG PG EG Sbjct: 752 PGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG 786 Score = 80.9 bits (198), Expect = 9e-16 Identities = 49/113 (43%), Positives = 58/113 (51%), Gaps = 26/113 (23%) Query: 26 GQANTGCYGIPGMPGLPGA------PGKD--GYDGLPGPKGEPGIPAIPGIRGP------ 71 G + G G PG PGL G+ PGKD G G PG G PG+P PG GP Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443 Query: 72 -KGQKGEPGLPGH------PGKNGPMGPPGM-----PGVPGPMGIPGEPGEEG 112 KG G+ GLPG+ PG +GP G PG+ P +PGP G+PG PG G Sbjct: 444 RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496 Score = 80.9 bits (198), Expect = 9e-16 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 12/98 (12%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDG-------LPGPKGEPGIPAIPGIRGPKGQKGEPG 79 Q G G G+PG PG PG+ G G +PGP G PG P PG +GP G G G Sbjct: 621 QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680 Query: 80 LPGHPGKNGPMGPPGMPGV-----PGPMGIPGEPGEEG 112 G PG GP G PG+PG+ PGP G G PG +G Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718 Score = 79.3 bits (194), Expect = 3e-15 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 23/106 (21%) Query: 31 GCYGIPGMPG---LPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG----------- 76 G GIPG G +PG+ GK G G PG G PG+P I G++G KG+ G Sbjct: 1009 GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068 Query: 77 ---EPGLPGHPGKNGPMGPPGMPGVPGPMG------IPGEPGEEGR 113 +PGLPG GK G MG PG PG GP G PG PG G+ Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK 1114 Score = 79.0 bits (193), Expect = 4e-15 Identities = 47/115 (40%), Positives = 52/115 (45%), Gaps = 27/115 (23%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP-------KGEP---------GIPAIPGI 68 RG+ G PG PG G+PG G G PGP KG P G P IPG+ Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 69 RGPKGQ-----------KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GPKG+ G PGLPG PG +G G PG G G G PG PG G Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520 Score = 79.0 bits (193), Expect = 4e-15 Identities = 41/95 (43%), Positives = 49/95 (51%), Gaps = 9/95 (9%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGP---------KGEPGIPAIPGIRGPKGQKGE 77 + + G G+ G G PGA G+ G G PGP KGEPG+ G G KG +G Sbjct: 915 RGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGV 974 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+PG G G GP G PG G +G G PGE G Sbjct: 975 PGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Score = 78.6 bits (192), Expect = 5e-15 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 7/90 (7%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP---GHPGK 86 T C IPG PGLPG PG G G+PG +G G+ PG G G G PG P G PG Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536 Query: 87 NGPMG----PPGMPGVPGPMGIPGEPGEEG 112 G G P G GVPG G+ G+PG +G Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566 Score = 78.2 bits (191), Expect = 6e-15 Identities = 40/89 (44%), Positives = 49/89 (55%), Gaps = 3/89 (3%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 + N G G+PG+ GL G PG G G G G G P PG+RG G G G+PG GK Sbjct: 969 KGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGK 1028 Query: 87 NGPMGPP---GMPGVPGPMGIPGEPGEEG 112 G +G P G PG+PG G+ G+ GE G Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057 Score = 77.8 bits (190), Expect = 8e-15 Identities = 37/78 (47%), Positives = 44/78 (56%) Query: 35 IPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPG 94 +PG PG PG PG+ G G PGP G PG G RG G+ G+PG PG G+ G G G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415 Query: 95 MPGVPGPMGIPGEPGEEG 112 PG G G+PG G+ G Sbjct: 1416 EPGPAGSDGLPGLKGKRG 1433 Score = 77.4 bits (189), Expect = 1e-14 Identities = 50/124 (40%), Positives = 55/124 (44%), Gaps = 35/124 (28%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP---KGEPGIPAI--------------- 65 L G++ G PG PGL G PGKDG G PG KG G P + Sbjct: 278 LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337 Query: 66 PGIRGP---------KGQKGEPGLPGHPGKNGPMGPPGMPGVPGP--------MGIPGEP 108 PG RGP KG +G PG PG G GP GP G PGVPG G PG P Sbjct: 338 PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397 Query: 109 GEEG 112 G +G Sbjct: 398 GLKG 401 Score = 77.4 bits (189), Expect = 1e-14 Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 29/108 (26%) Query: 34 GIPGMPGLPGAPGKDGYDG--LPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMG 91 G+PG+ GL G G+ GY PGP G G P +PG G KG+ G+PG PGH G GP G Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101 Query: 92 PPGMPGVPG---------------------------PMGIPGEPGEEG 112 PG PG PG P G+PG PG G Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Score = 76.6 bits (187), Expect = 2e-14 Identities = 40/98 (40%), Positives = 52/98 (53%), Gaps = 8/98 (8%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK---GQKGEPGL 80 L G +PG PG PG PG+ G G G G PG+P +PG G + G +G+PG Sbjct: 737 LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQ 796 Query: 81 PGHPGKNGP-----MGPPGMPGVPGPMGIPGEPGEEGR 113 PG PG+ GP GP G G+PG G+ G+ G G+ Sbjct: 797 PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834 Score = 76.6 bits (187), Expect = 2e-14 Identities = 41/89 (46%), Positives = 45/89 (50%), Gaps = 12/89 (13%) Query: 36 PGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP------ 89 PG PG G PG G G G G+PG P G GP+G G PG PG PGK GP Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 90 ------MGPPGMPGVPGPMGIPGEPGEEG 112 +GPPG+ G PG G PG PG G Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMG 1152 Score = 75.5 bits (184), Expect = 4e-14 Identities = 50/129 (38%), Positives = 54/129 (41%), Gaps = 46/129 (35%) Query: 30 TGCYGIPGMPGLPGA--PGKDGYDGLPGPKGEPGIPAIPG--------IRGPKGQKGEPG 79 TG G PG PGLPGA PG+ G G PG +G PG P PG I+G KG G PG Sbjct: 1218 TGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277 Query: 80 LPGHPGKNGPMGPPG---------------------MPGV---------------PGPMG 103 G PG G MGPPG PGV PGP+G Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337 Query: 104 IPGEPGEEG 112 G PG G Sbjct: 1338 PKGPPGVRG 1346 Score = 75.1 bits (183), Expect = 5e-14 Identities = 44/100 (44%), Positives = 49/100 (49%), Gaps = 18/100 (18%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGL---------PGPKGEPGIP---AIPGIRGPKGQKGEP 78 G G PG PG+ G PG+DG G+ PGP G PG P PGI G KGQ+G P Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930 Query: 79 GLPGHPGKNGPMGPP------GMPGVPGPMGIPGEPGEEG 112 G G G G GP G G PG G G PGE+G Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/137 (36%), Positives = 55/137 (40%), Gaps = 43/137 (31%) Query: 19 LLLLPLRGQANTGCYGIPGMPGLPGAP---------------GKDGYDGLPGPKGEPG-- 61 LL P + N G G G G PG P G G +G PGP G PG Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 62 IPAIPGIRGPKGQKGEPGLP--------------------GHPGKNGP------MGPPGM 95 IP G RGP G +G PG P GHPG GP MGPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 96 PGVPGPMGIPGEPGEEG 112 G PG G+PG G+ G Sbjct: 1294 LGAPGTPGLPGPRGDPG 1310 Score = 74.7 bits (182), Expect = 7e-14 Identities = 45/106 (42%), Positives = 48/106 (45%), Gaps = 19/106 (17%) Query: 27 QANTGCYGIPGMPGLPGAPGK---------DGYDGLPGPKGEPG--IPAIPGIRGPKGQK 75 Q G G PG PGLPG G G +G PGP G PG IP G RGP G + Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSR 1247 Query: 76 GEPGLPGHPGK--------NGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G PG PG PG G G G PG GP G G+ G GR Sbjct: 1248 GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Score = 74.7 bits (182), Expect = 7e-14 Identities = 40/97 (41%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Query: 23 PLRGQANTGCYGIPG------MPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG 76 P+ + G G PG +PG PG PG G G+ G G PG P G GP+G+ G Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 + G PG PG G G G G PGP G G PG +G+ Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGK 1431 Score = 74.3 bits (181), Expect = 9e-14 Identities = 45/104 (43%), Positives = 52/104 (50%), Gaps = 14/104 (13%) Query: 23 PLRGQANTGCYGIPGMPGLPGAP-----GKDGYDGLPGPKGEPGIPA--IPGIRGPKGQK 75 P + G G PG+PG PG+ G G+ GL G KGE G P G G G Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCA 423 Query: 76 GEPGLPGHPGKNGP-------MGPPGMPGVPGPMGIPGEPGEEG 112 G PGLPG PG GP GPPG G+PG +G PG PG +G Sbjct: 424 GSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDG 467 Score = 73.9 bits (180), Expect = 1e-13 Identities = 50/134 (37%), Positives = 57/134 (42%), Gaps = 17/134 (12%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPG--------PKGEPGIPAIPGIRGPKGQKGEP 78 Q G G G PG+PGA G G G P KG+PG+P P G +G P Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP------GPQGLP 185 Query: 79 GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLI 138 G PG PG GP GPPG G PG MG G G G + V T P P ++I Sbjct: 186 GPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVI 245 Query: 139 RFNAVLTNPQGDYD 152 LT P D Sbjct: 246 ---VTLTGPDNRTD 256 Score = 73.9 bits (180), Expect = 1e-13 Identities = 39/91 (42%), Positives = 46/91 (50%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG---------EPGLP 81 G G PG+ G G PG+ G G+PG G G+ +PG GP G +G EPGL Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG G MG PG G G +G PG G G Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Score = 73.9 bits (180), Expect = 1e-13 Identities = 41/94 (43%), Positives = 52/94 (55%), Gaps = 8/94 (8%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE------PGIPAIPGIRGPKGQKGEPGL 80 + + G G PG PGL G PG G G+PG KG+ PG PG+ G G +G+ G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055 Query: 81 PGHP--GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+ + GP GP G PG+PG MG GE G+ G Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089 Score = 73.6 bits (179), Expect = 2e-13 Identities = 44/113 (38%), Positives = 54/113 (47%), Gaps = 26/113 (23%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGPKGQKGEPGLPGHPGKN 87 G G+PGMPGL G G G G PGP+G+ G P PG+RG G G G+PG GK Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR 1029 Query: 88 GPMG------PPGMPGV-----------------PGPMGIPGEPGEEGRYKQK 117 G +G PG+PG+ PGP G G+PG G +K Sbjct: 1030 GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKK 1082 Score = 73.6 bits (179), Expect = 2e-13 Identities = 42/110 (38%), Positives = 52/110 (47%), Gaps = 19/110 (17%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGL------PGPKGEPGIPAIPGIRGP---KG 73 P + G G PG+PG PG G G+ G+ PG +G PG+P PG GP +G Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155 Query: 74 QKGEPGLPGHPGKN----------GPMGPPGMPGVPGPMGIPGEPGEEGR 113 +G G+PG G+ GP G PG G G G PG PG GR Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205 Score = 72.0 bits (175), Expect = 4e-13 Identities = 44/99 (44%), Positives = 48/99 (48%), Gaps = 17/99 (17%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPG-----IPAIPGIRGPKGQKGEPGLPGH-- 83 G G PG PG GA G G G PG G PG + PG G KG KGE G PG Sbjct: 354 GDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA 413 Query: 84 ---PGKNGPMGPPGMPGVPGPMGIPGE-------PGEEG 112 PG G G PG+PG PGP G PG+ PG+ G Sbjct: 414 MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Score = 71.6 bits (174), Expect = 6e-13 Identities = 37/78 (47%), Positives = 42/78 (53%), Gaps = 3/78 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G PGM G PG PG G G GP+G+PG PG GP G+KG G G P GP Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP---GPA 1420 Query: 91 GPPGMPGVPGPMGIPGEP 108 G G+PG+ G G G P Sbjct: 1421 GSDGLPGLKGKRGDSGSP 1438 Score = 71.2 bits (173), Expect = 7e-13 Identities = 38/83 (45%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNG---PM 90 G+ G G PG G G G+PG KG G+P G GP+G G G PG PG G M Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017 Query: 91 GPPGMPGVPGPMGIPGEPGEEGR 113 G GMPG G G G PG GR Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGR 1040 Score = 70.5 bits (171), Expect = 1e-12 Identities = 48/130 (36%), Positives = 53/130 (40%), Gaps = 39/130 (30%) Query: 22 LPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE---- 77 + L + + G G PG GLPG PG G G PGP G G P G RGPKG GE Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 78 -PGLPGHPGKNGPMGPPGM--------------------------PGVPGPMGIPGE--- 107 G G G GP GPPG PG PGP G+PGE Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284 Query: 108 -----PGEEG 112 PG+ G Sbjct: 285 SEKGAPGDPG 294 Score = 70.1 bits (170), Expect = 2e-12 Identities = 40/89 (44%), Positives = 44/89 (49%), Gaps = 12/89 (13%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI------PGIRGPKGQKGEPGLPGH 83 TG GIPG G G G+ GY G PG G PG + PG GP G G PG PG Sbjct: 855 TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG+PGV G G PG GE+G Sbjct: 915 ------RGSPGIPGVKGQRGTPGAKGEQG 937 Score = 68.6 bits (166), Expect = 5e-12 Identities = 43/103 (41%), Positives = 48/103 (46%), Gaps = 16/103 (15%) Query: 31 GCYGIPGMPGLPGA-----PGKDGYDGLPGPKGEPGIPAIPGIRGP-----------KGQ 74 G G+ G PG PG G D L G KG+ G PG GP KG Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 G+PGL G PGK+G G PG GV G G PG GE+G QK Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQK 332 Score = 61.6 bits (148), Expect = 6e-10 Identities = 41/110 (37%), Positives = 47/110 (42%), Gaps = 21/110 (19%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGKD--GYDGLPGPKGE------PGIPAIPGIRGPKGQ 74 L+G+ + G G PG PG G PG+ G PG G G+P PG G KG Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPM------------GIPGEPGEEG 112 +G PGL G G G G G PG GP G PG PG G Sbjct: 317 RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRG 366 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 3/56 (5%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP 78 P + G G PG PG G G G G PGP G G +PG++G +G G P Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG---LPGLKGKRGDSGSP 1438 Score = 34.3 bits (77), Expect = 0.10 Identities = 17/37 (45%), Positives = 19/37 (51%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRG 70 G G G PG G DG GL G +G+ G PA RG Sbjct: 1409 GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 32.3 bits (72), Expect = 0.39 Identities = 18/43 (41%), Positives = 20/43 (46%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG 73 G G G G G PG G DGLPG KG+ G P +G Sbjct: 1403 GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 95.9 bits (237), Expect = 3e-20 Identities = 47/92 (51%), Positives = 56/92 (60%), Gaps = 14/92 (15%) Query: 29 NTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG-----------QKGE 77 NTG YG+ G+PG G+ G+ G+ GLPG G PGIP G++G KG KG+ Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 PGLPG P GP G PG PG PGP+G PG PG Sbjct: 173 PGLPGAP---GPQGLPGPPGFPGPVGPPGPPG 201 Score = 90.1 bits (222), Expect = 2e-18 Identities = 56/145 (38%), Positives = 65/145 (44%), Gaps = 40/145 (27%) Query: 13 LKLLLLLLLLPLRGQANTGCY-------------------GIPGMPGLPGAPGKDGYDGL 53 L L LLL+LL A+ GC G PG PG PG G G +GL Sbjct: 12 LLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGL 71 Query: 54 PGPKGEPGIPAIPGIRGPKGQK---------GEPGLPGHPGKNGP------------MGP 92 PGP+G G P +PG+ G KG + G PGLPG PG GP G Sbjct: 72 PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131 Query: 93 PGMPGVPGPMGIPGEPGEEGRYKQK 117 G PG+PG +G PG PG G QK Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQK 156 Score = 89.4 bits (220), Expect = 3e-18 Identities = 48/102 (47%), Positives = 57/102 (55%), Gaps = 12/102 (11%) Query: 24 LRGQ----ANTGCYGIPGMPGLP--------GAPGKDGYDGLPGPKGEPGIPAIPGIRGP 71 L+GQ TG G PG+PGL G+PG G+ G GP G+ G P PGI GP Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 72 KGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G+ G G+ G PG GP GPPG PG PG G PG PG +G+ Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQ 926 Score = 88.2 bits (217), Expect = 6e-18 Identities = 50/100 (50%), Positives = 54/100 (54%), Gaps = 19/100 (19%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI--PGIRGPKGQKG--------------- 76 G G PG+PG+ GK G GLPGP GEPGIP I PG GPKG +G Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 77 EPGLPGHPGKNGPMGPP--GMPGVPGPMGIPGEPGEEGRY 114 EPGLPG PG G G P MPG PG G PGE G G + Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767 Score = 87.8 bits (216), Expect = 8e-18 Identities = 49/116 (42%), Positives = 59/116 (50%), Gaps = 12/116 (10%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG---IRGPKGQKGEPGLPGHPGKN 87 G G+PG PGL G PG+ G DG+PG G G+P G + G KG +G PG PG PG Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607 Query: 88 GP--------MGPPGMPGVPGPMGIPGEPGEEGRYKQKFQ-SVFTVTRQTHQPPAP 134 GP GP G PG+ G G+PG PG G + + SV T PP P Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Score = 86.3 bits (212), Expect = 2e-17 Identities = 47/106 (44%), Positives = 56/106 (52%), Gaps = 24/106 (22%) Query: 31 GCYGIPGMPGLPGAPGK------DGYDGLPGPKGE----------PGIPAIPGIRGPKGQ 74 G G PG+PG PG+PG G DG+PGP GE PG PG +G KG Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193 Query: 75 KGEPGLPGHPGKNG------PMGPPGMPGVPGPMGIPGE--PGEEG 112 +G PG PG PG+ G P GP G+ G PGP G+PG PG+ G Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/97 (44%), Positives = 53/97 (54%), Gaps = 11/97 (11%) Query: 31 GCYGIPGMPGLPGAPGKDGYDG-----------LPGPKGEPGIPAIPGIRGPKGQKGEPG 79 G +G+PG G PG PG DG G +PGP G PG+P + G++G G++G G Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508 Query: 80 LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQ 116 L G PG G G PG PG PG G PG GE+G Q Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/82 (52%), Positives = 47/82 (57%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G PG PG G G +G PG G PG+P PG G G KG GL G PG GP Sbjct: 1080 GKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 G PG PG PGPMGI G+ G +G Sbjct: 1140 GLPGFPGSPGPMGIRGDQGRDG 1161 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/91 (47%), Positives = 49/91 (53%), Gaps = 12/91 (13%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G G G PG G G GLPGP+G+PG PG++G KG G G G PG GP GPP Sbjct: 1283 GTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Query: 94 G------------MPGVPGPMGIPGEPGEEG 112 G +PG PGP G PGEPG +G Sbjct: 1343 GVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 85.1 bits (209), Expect = 5e-17 Identities = 42/87 (48%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPG 85 G+ G G G+PGL G G+ G G GPKG+PGIP + G G+ G PG+PGH G Sbjct: 807 GRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR-SGFPGETGSPGIPGHQG 865 Query: 86 KNGPMGPPGMPGVPGPMGIPGEPGEEG 112 + GP+G G PG PG +G PGE G G Sbjct: 866 EMGPLGQRGYPGNPGILGPPGEDGVIG 892 Score = 83.6 bits (205), Expect = 1e-16 Identities = 45/107 (42%), Positives = 51/107 (47%), Gaps = 24/107 (22%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI---------------PGIRGPKG-- 73 G G PG PGLPG G G+ G PG KGE G P PG+RG G Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351 Query: 74 -------QKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G PG PG PG G GPPG PG GP G G+PG++G+ Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGK 1398 Score = 83.2 bits (204), Expect = 2e-16 Identities = 41/82 (50%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G G PG+PG G G PGP G+ G I G+ GP G +G PGLPG PG GPM Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPM 1151 Query: 91 ---GPPGMPGVPGPMGIPGEPG 109 G G G+PGP G GE G Sbjct: 1152 GIRGDQGRDGIPGPAGEKGETG 1173 Score = 82.4 bits (202), Expect = 3e-16 Identities = 44/97 (45%), Positives = 52/97 (53%), Gaps = 15/97 (15%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQ------------KGEP 78 G G PG PG PG PG+ G G+PG KG+ G P G +G KG KGEP Sbjct: 898 GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 79 GL---PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GL G+PG+ G G PGMPG+ G G+PG G G Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG 994 Score = 82.0 bits (201), Expect = 4e-16 Identities = 48/117 (41%), Positives = 56/117 (47%), Gaps = 35/117 (29%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGP------------KGQKGEP 78 G G PG+PGL G+ G G GLPG G PG+P PG GP KG++G P Sbjct: 76 GPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFP 135 Query: 79 GLP---GHPG----------KNGP----------MGPPGMPGVPGPMGIPGEPGEEG 112 GLP G+PG K P G PG+PG PGP G+PG PG G Sbjct: 136 GLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPG 192 Score = 82.0 bits (201), Expect = 4e-16 Identities = 48/101 (47%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE--------PGIPAIPGIRGPKGQ 74 P Q G G G PG G PG G GLPG KGE PG P PG RG G+ Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGE 766 Query: 75 KGE------PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 GE PGLPG PG G GP G PG PGP G G PG Sbjct: 767 HGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807 Score = 81.6 bits (200), Expect = 6e-16 Identities = 44/101 (43%), Positives = 47/101 (46%), Gaps = 22/101 (21%) Query: 31 GCYGIPGMPGLPGA----------------------PGKDGYDGLPGPKGEPGIPAIPGI 68 G G+PG PG PGA PG G G PG KG GIP PG+ Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576 Query: 69 RGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 +G G KGE L G G GP G PG PG PGP G G PG Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Score = 81.6 bits (200), Expect = 6e-16 Identities = 51/124 (41%), Positives = 57/124 (45%), Gaps = 34/124 (27%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGK------DGYDGLPGPKGEPGIPAIPGIRGP----- 71 LRGQ G GIPG PG+ G PG G G GP G+PG P PG GP Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 72 ---------KGQKGEPGLPGHPGKNGPMG-------------PPGMPGVPGPMGIPGEPG 109 +G +G PG PG PG+ GP G PPG PG PGP G PG PG Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 110 EEGR 113 G+ Sbjct: 678 SLGK 681 Score = 81.6 bits (200), Expect = 6e-16 Identities = 44/95 (46%), Positives = 52/95 (54%), Gaps = 16/95 (16%) Query: 34 GIPGMPGL--PGAPGKDGYDGLPGPKG---------EPGIPAIPGIRGPKGQ-----KGE 77 G PG+PG+ PG PG G G PG KG EPG+P PG+ G KG+ G Sbjct: 692 GEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGG 751 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG PG PG+ G G G G+PG G+PG PG EG Sbjct: 752 PGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG 786 Score = 80.9 bits (198), Expect = 9e-16 Identities = 49/113 (43%), Positives = 58/113 (51%), Gaps = 26/113 (23%) Query: 26 GQANTGCYGIPGMPGLPGA------PGKD--GYDGLPGPKGEPGIPAIPGIRGP------ 71 G + G G PG PGL G+ PGKD G G PG G PG+P PG GP Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443 Query: 72 -KGQKGEPGLPGH------PGKNGPMGPPGM-----PGVPGPMGIPGEPGEEG 112 KG G+ GLPG+ PG +GP G PG+ P +PGP G+PG PG G Sbjct: 444 RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496 Score = 80.9 bits (198), Expect = 9e-16 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 12/98 (12%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDG-------LPGPKGEPGIPAIPGIRGPKGQKGEPG 79 Q G G G+PG PG PG+ G G +PGP G PG P PG +GP G G G Sbjct: 621 QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680 Query: 80 LPGHPGKNGPMGPPGMPGV-----PGPMGIPGEPGEEG 112 G PG GP G PG+PG+ PGP G G PG +G Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718 Score = 79.3 bits (194), Expect = 3e-15 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 23/106 (21%) Query: 31 GCYGIPGMPG---LPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG----------- 76 G GIPG G +PG+ GK G G PG G PG+P I G++G KG+ G Sbjct: 1009 GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068 Query: 77 ---EPGLPGHPGKNGPMGPPGMPGVPGPMG------IPGEPGEEGR 113 +PGLPG GK G MG PG PG GP G PG PG G+ Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK 1114 Score = 79.0 bits (193), Expect = 4e-15 Identities = 47/115 (40%), Positives = 52/115 (45%), Gaps = 27/115 (23%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP-------KGEP---------GIPAIPGI 68 RG+ G PG PG G+PG G G PGP KG P G P IPG+ Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 69 RGPKGQ-----------KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GPKG+ G PGLPG PG +G G PG G G G PG PG G Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520 Score = 79.0 bits (193), Expect = 4e-15 Identities = 41/95 (43%), Positives = 49/95 (51%), Gaps = 9/95 (9%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGP---------KGEPGIPAIPGIRGPKGQKGE 77 + + G G+ G G PGA G+ G G PGP KGEPG+ G G KG +G Sbjct: 915 RGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGV 974 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+PG G G GP G PG G +G G PGE G Sbjct: 975 PGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Score = 78.6 bits (192), Expect = 5e-15 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 7/90 (7%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP---GHPGK 86 T C IPG PGLPG PG G G+PG +G G+ PG G G G PG P G PG Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536 Query: 87 NGPMG----PPGMPGVPGPMGIPGEPGEEG 112 G G P G GVPG G+ G+PG +G Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566 Score = 78.2 bits (191), Expect = 6e-15 Identities = 40/89 (44%), Positives = 49/89 (55%), Gaps = 3/89 (3%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 + N G G+PG+ GL G PG G G G G G P PG+RG G G G+PG GK Sbjct: 969 KGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGK 1028 Query: 87 NGPMGPP---GMPGVPGPMGIPGEPGEEG 112 G +G P G PG+PG G+ G+ GE G Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057 Score = 77.8 bits (190), Expect = 8e-15 Identities = 37/78 (47%), Positives = 44/78 (56%) Query: 35 IPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPG 94 +PG PG PG PG+ G G PGP G PG G RG G+ G+PG PG G+ G G G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415 Query: 95 MPGVPGPMGIPGEPGEEG 112 PG G G+PG G+ G Sbjct: 1416 EPGPAGSDGLPGLKGKRG 1433 Score = 77.4 bits (189), Expect = 1e-14 Identities = 50/124 (40%), Positives = 55/124 (44%), Gaps = 35/124 (28%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP---KGEPGIPAI--------------- 65 L G++ G PG PGL G PGKDG G PG KG G P + Sbjct: 278 LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337 Query: 66 PGIRGP---------KGQKGEPGLPGHPGKNGPMGPPGMPGVPGP--------MGIPGEP 108 PG RGP KG +G PG PG G GP GP G PGVPG G PG P Sbjct: 338 PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397 Query: 109 GEEG 112 G +G Sbjct: 398 GLKG 401 Score = 77.4 bits (189), Expect = 1e-14 Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 29/108 (26%) Query: 34 GIPGMPGLPGAPGKDGYDG--LPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMG 91 G+PG+ GL G G+ GY PGP G G P +PG G KG+ G+PG PGH G GP G Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101 Query: 92 PPGMPGVPG---------------------------PMGIPGEPGEEG 112 PG PG PG P G+PG PG G Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Score = 76.6 bits (187), Expect = 2e-14 Identities = 40/98 (40%), Positives = 52/98 (53%), Gaps = 8/98 (8%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK---GQKGEPGL 80 L G +PG PG PG PG+ G G G G PG+P +PG G + G +G+PG Sbjct: 737 LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQ 796 Query: 81 PGHPGKNGP-----MGPPGMPGVPGPMGIPGEPGEEGR 113 PG PG+ GP GP G G+PG G+ G+ G G+ Sbjct: 797 PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834 Score = 76.6 bits (187), Expect = 2e-14 Identities = 41/89 (46%), Positives = 45/89 (50%), Gaps = 12/89 (13%) Query: 36 PGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP------ 89 PG PG G PG G G G G+PG P G GP+G G PG PG PGK GP Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 90 ------MGPPGMPGVPGPMGIPGEPGEEG 112 +GPPG+ G PG G PG PG G Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMG 1152 Score = 75.5 bits (184), Expect = 4e-14 Identities = 50/129 (38%), Positives = 54/129 (41%), Gaps = 46/129 (35%) Query: 30 TGCYGIPGMPGLPGA--PGKDGYDGLPGPKGEPGIPAIPG--------IRGPKGQKGEPG 79 TG G PG PGLPGA PG+ G G PG +G PG P PG I+G KG G PG Sbjct: 1218 TGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277 Query: 80 LPGHPGKNGPMGPPG---------------------MPGV---------------PGPMG 103 G PG G MGPPG PGV PGP+G Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337 Query: 104 IPGEPGEEG 112 G PG G Sbjct: 1338 PKGPPGVRG 1346 Score = 75.1 bits (183), Expect = 5e-14 Identities = 44/100 (44%), Positives = 49/100 (49%), Gaps = 18/100 (18%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGL---------PGPKGEPGIP---AIPGIRGPKGQKGEP 78 G G PG PG+ G PG+DG G+ PGP G PG P PGI G KGQ+G P Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930 Query: 79 GLPGHPGKNGPMGPP------GMPGVPGPMGIPGEPGEEG 112 G G G G GP G G PG G G PGE+G Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/137 (36%), Positives = 55/137 (40%), Gaps = 43/137 (31%) Query: 19 LLLLPLRGQANTGCYGIPGMPGLPGAP---------------GKDGYDGLPGPKGEPG-- 61 LL P + N G G G G PG P G G +G PGP G PG Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 62 IPAIPGIRGPKGQKGEPGLP--------------------GHPGKNGP------MGPPGM 95 IP G RGP G +G PG P GHPG GP MGPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 96 PGVPGPMGIPGEPGEEG 112 G PG G+PG G+ G Sbjct: 1294 LGAPGTPGLPGPRGDPG 1310 Score = 74.7 bits (182), Expect = 7e-14 Identities = 45/106 (42%), Positives = 48/106 (45%), Gaps = 19/106 (17%) Query: 27 QANTGCYGIPGMPGLPGAPGK---------DGYDGLPGPKGEPG--IPAIPGIRGPKGQK 75 Q G G PG PGLPG G G +G PGP G PG IP G RGP G + Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSR 1247 Query: 76 GEPGLPGHPGK--------NGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G PG PG PG G G G PG GP G G+ G GR Sbjct: 1248 GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Score = 74.7 bits (182), Expect = 7e-14 Identities = 40/97 (41%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Query: 23 PLRGQANTGCYGIPG------MPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG 76 P+ + G G PG +PG PG PG G G+ G G PG P G GP+G+ G Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 + G PG PG G G G G PGP G G PG +G+ Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGK 1431 Score = 74.3 bits (181), Expect = 9e-14 Identities = 45/104 (43%), Positives = 52/104 (50%), Gaps = 14/104 (13%) Query: 23 PLRGQANTGCYGIPGMPGLPGAP-----GKDGYDGLPGPKGEPGIPA--IPGIRGPKGQK 75 P + G G PG+PG PG+ G G+ GL G KGE G P G G G Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCA 423 Query: 76 GEPGLPGHPGKNGP-------MGPPGMPGVPGPMGIPGEPGEEG 112 G PGLPG PG GP GPPG G+PG +G PG PG +G Sbjct: 424 GSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDG 467 Score = 73.9 bits (180), Expect = 1e-13 Identities = 50/134 (37%), Positives = 57/134 (42%), Gaps = 17/134 (12%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPG--------PKGEPGIPAIPGIRGPKGQKGEP 78 Q G G G PG+PGA G G G P KG+PG+P P G +G P Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP------GPQGLP 185 Query: 79 GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLI 138 G PG PG GP GPPG G PG MG G G G + V T P P ++I Sbjct: 186 GPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVI 245 Query: 139 RFNAVLTNPQGDYD 152 LT P D Sbjct: 246 ---VTLTGPDNRTD 256 Score = 73.9 bits (180), Expect = 1e-13 Identities = 39/91 (42%), Positives = 46/91 (50%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG---------EPGLP 81 G G PG+ G G PG+ G G+PG G G+ +PG GP G +G EPGL Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG G MG PG G G +G PG G G Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Score = 73.9 bits (180), Expect = 1e-13 Identities = 41/94 (43%), Positives = 52/94 (55%), Gaps = 8/94 (8%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE------PGIPAIPGIRGPKGQKGEPGL 80 + + G G PG PGL G PG G G+PG KG+ PG PG+ G G +G+ G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055 Query: 81 PGHP--GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+ + GP GP G PG+PG MG GE G+ G Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089 Score = 73.6 bits (179), Expect = 2e-13 Identities = 44/113 (38%), Positives = 54/113 (47%), Gaps = 26/113 (23%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGPKGQKGEPGLPGHPGKN 87 G G+PGMPGL G G G G PGP+G+ G P PG+RG G G G+PG GK Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR 1029 Query: 88 GPMG------PPGMPGV-----------------PGPMGIPGEPGEEGRYKQK 117 G +G PG+PG+ PGP G G+PG G +K Sbjct: 1030 GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKK 1082 Score = 73.6 bits (179), Expect = 2e-13 Identities = 42/110 (38%), Positives = 52/110 (47%), Gaps = 19/110 (17%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGL------PGPKGEPGIPAIPGIRGP---KG 73 P + G G PG+PG PG G G+ G+ PG +G PG+P PG GP +G Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155 Query: 74 QKGEPGLPGHPGKN----------GPMGPPGMPGVPGPMGIPGEPGEEGR 113 +G G+PG G+ GP G PG G G G PG PG GR Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205 Score = 72.0 bits (175), Expect = 4e-13 Identities = 44/99 (44%), Positives = 48/99 (48%), Gaps = 17/99 (17%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPG-----IPAIPGIRGPKGQKGEPGLPGH-- 83 G G PG PG GA G G G PG G PG + PG G KG KGE G PG Sbjct: 354 GDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA 413 Query: 84 ---PGKNGPMGPPGMPGVPGPMGIPGE-------PGEEG 112 PG G G PG+PG PGP G PG+ PG+ G Sbjct: 414 MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Score = 71.6 bits (174), Expect = 6e-13 Identities = 37/78 (47%), Positives = 42/78 (53%), Gaps = 3/78 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G PGM G PG PG G G GP+G+PG PG GP G+KG G G P GP Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP---GPA 1420 Query: 91 GPPGMPGVPGPMGIPGEP 108 G G+PG+ G G G P Sbjct: 1421 GSDGLPGLKGKRGDSGSP 1438 Score = 71.2 bits (173), Expect = 7e-13 Identities = 38/83 (45%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNG---PM 90 G+ G G PG G G G+PG KG G+P G GP+G G G PG PG G M Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017 Query: 91 GPPGMPGVPGPMGIPGEPGEEGR 113 G GMPG G G G PG GR Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGR 1040 Score = 70.5 bits (171), Expect = 1e-12 Identities = 48/130 (36%), Positives = 53/130 (40%), Gaps = 39/130 (30%) Query: 22 LPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE---- 77 + L + + G G PG GLPG PG G G PGP G G P G RGPKG GE Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 78 -PGLPGHPGKNGPMGPPGM--------------------------PGVPGPMGIPGE--- 107 G G G GP GPPG PG PGP G+PGE Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284 Query: 108 -----PGEEG 112 PG+ G Sbjct: 285 SEKGAPGDPG 294 Score = 70.1 bits (170), Expect = 2e-12 Identities = 40/89 (44%), Positives = 44/89 (49%), Gaps = 12/89 (13%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI------PGIRGPKGQKGEPGLPGH 83 TG GIPG G G G+ GY G PG G PG + PG GP G G PG PG Sbjct: 855 TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG+PGV G G PG GE+G Sbjct: 915 ------RGSPGIPGVKGQRGTPGAKGEQG 937 Score = 68.6 bits (166), Expect = 5e-12 Identities = 43/103 (41%), Positives = 48/103 (46%), Gaps = 16/103 (15%) Query: 31 GCYGIPGMPGLPGA-----PGKDGYDGLPGPKGEPGIPAIPGIRGP-----------KGQ 74 G G+ G PG PG G D L G KG+ G PG GP KG Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 G+PGL G PGK+G G PG GV G G PG GE+G QK Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQK 332 Score = 61.6 bits (148), Expect = 6e-10 Identities = 41/110 (37%), Positives = 47/110 (42%), Gaps = 21/110 (19%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGKD--GYDGLPGPKGE------PGIPAIPGIRGPKGQ 74 L+G+ + G G PG PG G PG+ G PG G G+P PG G KG Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPM------------GIPGEPGEEG 112 +G PGL G G G G G PG GP G PG PG G Sbjct: 317 RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRG 366 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 3/56 (5%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP 78 P + G G PG PG G G G G PGP G G +PG++G +G G P Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG---LPGLKGKRGDSGSP 1438 Score = 34.3 bits (77), Expect = 0.10 Identities = 17/37 (45%), Positives = 19/37 (51%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRG 70 G G G PG G DG GL G +G+ G PA RG Sbjct: 1409 GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 32.3 bits (72), Expect = 0.39 Identities = 18/43 (41%), Positives = 20/43 (46%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG 73 G G G G G PG G DGLPG KG+ G P +G Sbjct: 1403 GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 95.9 bits (237), Expect = 3e-20 Identities = 47/92 (51%), Positives = 56/92 (60%), Gaps = 14/92 (15%) Query: 29 NTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG-----------QKGE 77 NTG YG+ G+PG G+ G+ G+ GLPG G PGIP G++G KG KG+ Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGD 172 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 PGLPG P GP G PG PG PGP+G PG PG Sbjct: 173 PGLPGAP---GPQGLPGPPGFPGPVGPPGPPG 201 Score = 90.1 bits (222), Expect = 2e-18 Identities = 56/145 (38%), Positives = 65/145 (44%), Gaps = 40/145 (27%) Query: 13 LKLLLLLLLLPLRGQANTGCY-------------------GIPGMPGLPGAPGKDGYDGL 53 L L LLL+LL A+ GC G PG PG PG G G +GL Sbjct: 12 LLLPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGL 71 Query: 54 PGPKGEPGIPAIPGIRGPKGQK---------GEPGLPGHPGKNGP------------MGP 92 PGP+G G P +PG+ G KG + G PGLPG PG GP G Sbjct: 72 PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131 Query: 93 PGMPGVPGPMGIPGEPGEEGRYKQK 117 G PG+PG +G PG PG G QK Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQK 156 Score = 89.4 bits (220), Expect = 3e-18 Identities = 48/102 (47%), Positives = 57/102 (55%), Gaps = 12/102 (11%) Query: 24 LRGQ----ANTGCYGIPGMPGLP--------GAPGKDGYDGLPGPKGEPGIPAIPGIRGP 71 L+GQ TG G PG+PGL G+PG G+ G GP G+ G P PGI GP Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 72 KGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G+ G G+ G PG GP GPPG PG PG G PG PG +G+ Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQ 926 Score = 88.2 bits (217), Expect = 6e-18 Identities = 50/100 (50%), Positives = 54/100 (54%), Gaps = 19/100 (19%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI--PGIRGPKGQKG--------------- 76 G G PG+PG+ GK G GLPGP GEPGIP I PG GPKG +G Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 77 EPGLPGHPGKNGPMGPP--GMPGVPGPMGIPGEPGEEGRY 114 EPGLPG PG G G P MPG PG G PGE G G + Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767 Score = 87.8 bits (216), Expect = 8e-18 Identities = 49/116 (42%), Positives = 59/116 (50%), Gaps = 12/116 (10%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPG---IRGPKGQKGEPGLPGHPGKN 87 G G+PG PGL G PG+ G DG+PG G G+P G + G KG +G PG PG PG Sbjct: 548 GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP 607 Query: 88 GP--------MGPPGMPGVPGPMGIPGEPGEEGRYKQKFQ-SVFTVTRQTHQPPAP 134 GP GP G PG+ G G+PG PG G + + SV T PP P Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Score = 86.3 bits (212), Expect = 2e-17 Identities = 47/106 (44%), Positives = 56/106 (52%), Gaps = 24/106 (22%) Query: 31 GCYGIPGMPGLPGAPGK------DGYDGLPGPKGE----------PGIPAIPGIRGPKGQ 74 G G PG+PG PG+PG G DG+PGP GE PG PG +G KG Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193 Query: 75 KGEPGLPGHPGKNG------PMGPPGMPGVPGPMGIPGE--PGEEG 112 +G PG PG PG+ G P GP G+ G PGP G+PG PG+ G Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/97 (44%), Positives = 53/97 (54%), Gaps = 11/97 (11%) Query: 31 GCYGIPGMPGLPGAPGKDGYDG-----------LPGPKGEPGIPAIPGIRGPKGQKGEPG 79 G +G+PG G PG PG DG G +PGP G PG+P + G++G G++G G Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508 Query: 80 LPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQ 116 L G PG G G PG PG PG G PG GE+G Q Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/82 (52%), Positives = 47/82 (57%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G PG PG G G +G PG G PG+P PG G G KG GL G PG GP Sbjct: 1080 GKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 91 GPPGMPGVPGPMGIPGEPGEEG 112 G PG PG PGPMGI G+ G +G Sbjct: 1140 GLPGFPGSPGPMGIRGDQGRDG 1161 Score = 85.9 bits (211), Expect = 3e-17 Identities = 43/91 (47%), Positives = 49/91 (53%), Gaps = 12/91 (13%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPP 93 G G G PG G G GLPGP+G+PG PG++G KG G G G PG GP GPP Sbjct: 1283 GTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Query: 94 G------------MPGVPGPMGIPGEPGEEG 112 G +PG PGP G PGEPG +G Sbjct: 1343 GVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373 Score = 85.1 bits (209), Expect = 5e-17 Identities = 42/87 (48%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Query: 26 GQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPG 85 G+ G G G+PGL G G+ G G GPKG+PGIP + G G+ G PG+PGH G Sbjct: 807 GRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR-SGFPGETGSPGIPGHQG 865 Query: 86 KNGPMGPPGMPGVPGPMGIPGEPGEEG 112 + GP+G G PG PG +G PGE G G Sbjct: 866 EMGPLGQRGYPGNPGILGPPGEDGVIG 892 Score = 83.6 bits (205), Expect = 1e-16 Identities = 45/107 (42%), Positives = 51/107 (47%), Gaps = 24/107 (22%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI---------------PGIRGPKG-- 73 G G PG PGLPG G G+ G PG KGE G P PG+RG G Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351 Query: 74 -------QKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G PG PG PG G GPPG PG GP G G+PG++G+ Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGK 1398 Score = 83.2 bits (204), Expect = 2e-16 Identities = 41/82 (50%), Positives = 46/82 (56%), Gaps = 3/82 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G G G PG+PG G G PGP G+ G I G+ GP G +G PGLPG PG GPM Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPM 1151 Query: 91 ---GPPGMPGVPGPMGIPGEPG 109 G G G+PGP G GE G Sbjct: 1152 GIRGDQGRDGIPGPAGEKGETG 1173 Score = 82.4 bits (202), Expect = 3e-16 Identities = 44/97 (45%), Positives = 52/97 (53%), Gaps = 15/97 (15%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQ------------KGEP 78 G G PG PG PG PG+ G G+PG KG+ G P G +G KG KGEP Sbjct: 898 GAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 79 GL---PGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GL G+PG+ G G PGMPG+ G G+PG G G Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPG 994 Score = 82.0 bits (201), Expect = 4e-16 Identities = 48/117 (41%), Positives = 56/117 (47%), Gaps = 35/117 (29%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGP------------KGQKGEP 78 G G PG+PGL G+ G G GLPG G PG+P PG GP KG++G P Sbjct: 76 GPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFP 135 Query: 79 GLP---GHPG----------KNGP----------MGPPGMPGVPGPMGIPGEPGEEG 112 GLP G+PG K P G PG+PG PGP G+PG PG G Sbjct: 136 GLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPG 192 Score = 82.0 bits (201), Expect = 4e-16 Identities = 48/101 (47%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE--------PGIPAIPGIRGPKGQ 74 P Q G G G PG G PG G GLPG KGE PG P PG RG G+ Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGE 766 Query: 75 KGE------PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 GE PGLPG PG G GP G PG PGP G G PG Sbjct: 767 HGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807 Score = 81.6 bits (200), Expect = 6e-16 Identities = 44/101 (43%), Positives = 47/101 (46%), Gaps = 22/101 (21%) Query: 31 GCYGIPGMPGLPGA----------------------PGKDGYDGLPGPKGEPGIPAIPGI 68 G G+PG PG PGA PG G G PG KG GIP PG+ Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576 Query: 69 RGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPG 109 +G G KGE L G G GP G PG PG PGP G G PG Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Score = 81.6 bits (200), Expect = 6e-16 Identities = 51/124 (41%), Positives = 57/124 (45%), Gaps = 34/124 (27%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGK------DGYDGLPGPKGEPGIPAIPGIRGP----- 71 LRGQ G GIPG PG+ G PG G G GP G+PG P PG GP Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG 617 Query: 72 ---------KGQKGEPGLPGHPGKNGPMG-------------PPGMPGVPGPMGIPGEPG 109 +G +G PG PG PG+ GP G PPG PG PGP G PG PG Sbjct: 618 YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 110 EEGR 113 G+ Sbjct: 678 SLGK 681 Score = 81.6 bits (200), Expect = 6e-16 Identities = 44/95 (46%), Positives = 52/95 (54%), Gaps = 16/95 (16%) Query: 34 GIPGMPGL--PGAPGKDGYDGLPGPKG---------EPGIPAIPGIRGPKGQ-----KGE 77 G PG+PG+ PG PG G G PG KG EPG+P PG+ G KG+ G Sbjct: 692 GEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGG 751 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG PG PG+ G G G G+PG G+PG PG EG Sbjct: 752 PGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG 786 Score = 80.9 bits (198), Expect = 9e-16 Identities = 49/113 (43%), Positives = 58/113 (51%), Gaps = 26/113 (23%) Query: 26 GQANTGCYGIPGMPGLPGA------PGKD--GYDGLPGPKGEPGIPAIPGIRGP------ 71 G + G G PG PGL G+ PGKD G G PG G PG+P PG GP Sbjct: 384 GSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVF 443 Query: 72 -KGQKGEPGLPGH------PGKNGPMGPPGM-----PGVPGPMGIPGEPGEEG 112 KG G+ GLPG+ PG +GP G PG+ P +PGP G+PG PG G Sbjct: 444 RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496 Score = 80.9 bits (198), Expect = 9e-16 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 12/98 (12%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDG-------LPGPKGEPGIPAIPGIRGPKGQKGEPG 79 Q G G G+PG PG PG+ G G +PGP G PG P PG +GP G G G Sbjct: 621 QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680 Query: 80 LPGHPGKNGPMGPPGMPGV-----PGPMGIPGEPGEEG 112 G PG GP G PG+PG+ PGP G G PG +G Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718 Score = 79.3 bits (194), Expect = 3e-15 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 23/106 (21%) Query: 31 GCYGIPGMPG---LPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG----------- 76 G GIPG G +PG+ GK G G PG G PG+P I G++G KG+ G Sbjct: 1009 GLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068 Query: 77 ---EPGLPGHPGKNGPMGPPGMPGVPGPMG------IPGEPGEEGR 113 +PGLPG GK G MG PG PG GP G PG PG G+ Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK 1114 Score = 79.0 bits (193), Expect = 4e-15 Identities = 47/115 (40%), Positives = 52/115 (45%), Gaps = 27/115 (23%) Query: 25 RGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP-------KGEP---------GIPAIPGI 68 RG+ G PG PG G+PG G G PGP KG P G P IPG+ Sbjct: 406 RGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGV 465 Query: 69 RGPKGQ-----------KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 GPKG+ G PGLPG PG +G G PG G G G PG PG G Sbjct: 466 DGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520 Score = 79.0 bits (193), Expect = 4e-15 Identities = 41/95 (43%), Positives = 49/95 (51%), Gaps = 9/95 (9%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGP---------KGEPGIPAIPGIRGPKGQKGE 77 + + G G+ G G PGA G+ G G PGP KGEPG+ G G KG +G Sbjct: 915 RGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGV 974 Query: 78 PGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+PG G G GP G PG G +G G PGE G Sbjct: 975 PGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Score = 78.6 bits (192), Expect = 5e-15 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 7/90 (7%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLP---GHPGK 86 T C IPG PGLPG PG G G+PG +G G+ PG G G G PG P G PG Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536 Query: 87 NGPMG----PPGMPGVPGPMGIPGEPGEEG 112 G G P G GVPG G+ G+PG +G Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566 Score = 78.2 bits (191), Expect = 6e-15 Identities = 40/89 (44%), Positives = 49/89 (55%), Gaps = 3/89 (3%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGK 86 + N G G+PG+ GL G PG G G G G G P PG+RG G G G+PG GK Sbjct: 969 KGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGK 1028 Query: 87 NGPMGPP---GMPGVPGPMGIPGEPGEEG 112 G +G P G PG+PG G+ G+ GE G Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPG 1057 Score = 77.8 bits (190), Expect = 8e-15 Identities = 37/78 (47%), Positives = 44/78 (56%) Query: 35 IPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPG 94 +PG PG PG PG+ G G PGP G PG G RG G+ G+PG PG G+ G G G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415 Query: 95 MPGVPGPMGIPGEPGEEG 112 PG G G+PG G+ G Sbjct: 1416 EPGPAGSDGLPGLKGKRG 1433 Score = 77.4 bits (189), Expect = 1e-14 Identities = 50/124 (40%), Positives = 55/124 (44%), Gaps = 35/124 (28%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGP---KGEPGIPAI--------------- 65 L G++ G PG PGL G PGKDG G PG KG G P + Sbjct: 278 LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337 Query: 66 PGIRGP---------KGQKGEPGLPGHPGKNGPMGPPGMPGVPGP--------MGIPGEP 108 PG RGP KG +G PG PG G GP GP G PGVPG G PG P Sbjct: 338 PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397 Query: 109 GEEG 112 G +G Sbjct: 398 GLKG 401 Score = 77.4 bits (189), Expect = 1e-14 Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 29/108 (26%) Query: 34 GIPGMPGLPGAPGKDGYDG--LPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMG 91 G+PG+ GL G G+ GY PGP G G P +PG G KG+ G+PG PGH G GP G Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101 Query: 92 PPGMPGVPG---------------------------PMGIPGEPGEEG 112 PG PG PG P G+PG PG G Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Score = 76.6 bits (187), Expect = 2e-14 Identities = 40/98 (40%), Positives = 52/98 (53%), Gaps = 8/98 (8%) Query: 24 LRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPK---GQKGEPGL 80 L G +PG PG PG PG+ G G G G PG+P +PG G + G +G+PG Sbjct: 737 LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQ 796 Query: 81 PGHPGKNGP-----MGPPGMPGVPGPMGIPGEPGEEGR 113 PG PG+ GP GP G G+PG G+ G+ G G+ Sbjct: 797 PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834 Score = 76.6 bits (187), Expect = 2e-14 Identities = 41/89 (46%), Positives = 45/89 (50%), Gaps = 12/89 (13%) Query: 36 PGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGP------ 89 PG PG G PG G G G G+PG P G GP+G G PG PG PGK GP Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 90 ------MGPPGMPGVPGPMGIPGEPGEEG 112 +GPPG+ G PG G PG PG G Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMG 1152 Score = 75.5 bits (184), Expect = 4e-14 Identities = 50/129 (38%), Positives = 54/129 (41%), Gaps = 46/129 (35%) Query: 30 TGCYGIPGMPGLPGA--PGKDGYDGLPGPKGEPGIPAIPG--------IRGPKGQKGEPG 79 TG G PG PGLPGA PG+ G G PG +G PG P PG I+G KG G PG Sbjct: 1218 TGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277 Query: 80 LPGHPGKNGPMGPPG---------------------MPGV---------------PGPMG 103 G PG G MGPPG PGV PGP+G Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337 Query: 104 IPGEPGEEG 112 G PG G Sbjct: 1338 PKGPPGVRG 1346 Score = 75.1 bits (183), Expect = 5e-14 Identities = 44/100 (44%), Positives = 49/100 (49%), Gaps = 18/100 (18%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGL---------PGPKGEPGIP---AIPGIRGPKGQKGEP 78 G G PG PG+ G PG+DG G+ PGP G PG P PGI G KGQ+G P Sbjct: 871 GQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTP 930 Query: 79 GLPGHPGKNGPMGPP------GMPGVPGPMGIPGEPGEEG 112 G G G G GP G G PG G G PGE+G Sbjct: 931 GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/137 (36%), Positives = 55/137 (40%), Gaps = 43/137 (31%) Query: 19 LLLLPLRGQANTGCYGIPGMPGLPGAP---------------GKDGYDGLPGPKGEPG-- 61 LL P + N G G G G PG P G G +G PGP G PG Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 62 IPAIPGIRGPKGQKGEPGLP--------------------GHPGKNGP------MGPPGM 95 IP G RGP G +G PG P GHPG GP MGPPG Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Query: 96 PGVPGPMGIPGEPGEEG 112 G PG G+PG G+ G Sbjct: 1294 LGAPGTPGLPGPRGDPG 1310 Score = 74.7 bits (182), Expect = 7e-14 Identities = 45/106 (42%), Positives = 48/106 (45%), Gaps = 19/106 (17%) Query: 27 QANTGCYGIPGMPGLPGAPGK---------DGYDGLPGPKGEPG--IPAIPGIRGPKGQK 75 Q G G PG PGLPG G G +G PGP G PG IP G RGP G + Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSR 1247 Query: 76 GEPGLPGHPGK--------NGPMGPPGMPGVPGPMGIPGEPGEEGR 113 G PG PG PG G G G PG GP G G+ G GR Sbjct: 1248 GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGR 1293 Score = 74.7 bits (182), Expect = 7e-14 Identities = 40/97 (41%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Query: 23 PLRGQANTGCYGIPG------MPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG 76 P+ + G G PG +PG PG PG G G+ G G PG P G GP+G+ G Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394 Query: 77 EPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGR 113 + G PG PG G G G G PGP G G PG +G+ Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGK 1431 Score = 74.3 bits (181), Expect = 9e-14 Identities = 45/104 (43%), Positives = 52/104 (50%), Gaps = 14/104 (13%) Query: 23 PLRGQANTGCYGIPGMPGLPGAP-----GKDGYDGLPGPKGEPGIPA--IPGIRGPKGQK 75 P + G G PG+PG PG+ G G+ GL G KGE G P G G G Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCA 423 Query: 76 GEPGLPGHPGKNGP-------MGPPGMPGVPGPMGIPGEPGEEG 112 G PGLPG PG GP GPPG G+PG +G PG PG +G Sbjct: 424 GSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDG 467 Score = 73.9 bits (180), Expect = 1e-13 Identities = 50/134 (37%), Positives = 57/134 (42%), Gaps = 17/134 (12%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPG--------PKGEPGIPAIPGIRGPKGQKGEP 78 Q G G G PG+PGA G G G P KG+PG+P P G +G P Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP------GPQGLP 185 Query: 79 GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLI 138 G PG PG GP GPPG G PG MG G G G + V T P P ++I Sbjct: 186 GPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVI 245 Query: 139 RFNAVLTNPQGDYD 152 LT P D Sbjct: 246 ---VTLTGPDNRTD 256 Score = 73.9 bits (180), Expect = 1e-13 Identities = 39/91 (42%), Positives = 46/91 (50%), Gaps = 9/91 (9%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKG---------EPGLP 81 G G PG+ G G PG+ G G+PG G G+ +PG GP G +G EPGL Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 82 GHPGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG G MG PG G G +G PG G G Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Score = 73.9 bits (180), Expect = 1e-13 Identities = 41/94 (43%), Positives = 52/94 (55%), Gaps = 8/94 (8%) Query: 27 QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGE------PGIPAIPGIRGPKGQKGEPGL 80 + + G G PG PGL G PG G G+PG KG+ PG PG+ G G +G+ G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055 Query: 81 PGHP--GKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 PG+ + GP GP G PG+PG MG GE G+ G Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089 Score = 73.6 bits (179), Expect = 2e-13 Identities = 44/113 (38%), Positives = 54/113 (47%), Gaps = 26/113 (23%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGE---PGIPAIPGIRGPKGQKGEPGLPGHPGKN 87 G G+PGMPGL G G G G PGP+G+ G P PG+RG G G G+PG GK Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR 1029 Query: 88 GPMG------PPGMPGV-----------------PGPMGIPGEPGEEGRYKQK 117 G +G PG+PG+ PGP G G+PG G +K Sbjct: 1030 GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKK 1082 Score = 73.6 bits (179), Expect = 2e-13 Identities = 42/110 (38%), Positives = 52/110 (47%), Gaps = 19/110 (17%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGL------PGPKGEPGIPAIPGIRGP---KG 73 P + G G PG+PG PG G G+ G+ PG +G PG+P PG GP +G Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155 Query: 74 QKGEPGLPGHPGKN----------GPMGPPGMPGVPGPMGIPGEPGEEGR 113 +G G+PG G+ GP G PG G G G PG PG GR Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205 Score = 72.0 bits (175), Expect = 4e-13 Identities = 44/99 (44%), Positives = 48/99 (48%), Gaps = 17/99 (17%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPG-----IPAIPGIRGPKGQKGEPGLPGH-- 83 G G PG PG GA G G G PG G PG + PG G KG KGE G PG Sbjct: 354 GDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA 413 Query: 84 ---PGKNGPMGPPGMPGVPGPMGIPGE-------PGEEG 112 PG G G PG+PG PGP G PG+ PG+ G Sbjct: 414 MGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Score = 71.6 bits (174), Expect = 6e-13 Identities = 37/78 (47%), Positives = 42/78 (53%), Gaps = 3/78 (3%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90 G G PGM G PG PG G G GP+G+PG PG GP G+KG G G P GP Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP---GPA 1420 Query: 91 GPPGMPGVPGPMGIPGEP 108 G G+PG+ G G G P Sbjct: 1421 GSDGLPGLKGKRGDSGSP 1438 Score = 71.2 bits (173), Expect = 7e-13 Identities = 38/83 (45%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNG---PM 90 G+ G G PG G G G+PG KG G+P G GP+G G G PG PG G M Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM 1017 Query: 91 GPPGMPGVPGPMGIPGEPGEEGR 113 G GMPG G G G PG GR Sbjct: 1018 GNMGMPGSKGKRGTLGFPGRAGR 1040 Score = 70.5 bits (171), Expect = 1e-12 Identities = 48/130 (36%), Positives = 53/130 (40%), Gaps = 39/130 (30%) Query: 22 LPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGE---- 77 + L + + G G PG GLPG PG G G PGP G G P G RGPKG GE Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 78 -PGLPGHPGKNGPMGPPGM--------------------------PGVPGPMGIPGE--- 107 G G G GP GPPG PG PGP G+PGE Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284 Query: 108 -----PGEEG 112 PG+ G Sbjct: 285 SEKGAPGDPG 294 Score = 70.1 bits (170), Expect = 2e-12 Identities = 40/89 (44%), Positives = 44/89 (49%), Gaps = 12/89 (13%) Query: 30 TGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAI------PGIRGPKGQKGEPGLPGH 83 TG GIPG G G G+ GY G PG G PG + PG GP G G PG PG Sbjct: 855 TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914 Query: 84 PGKNGPMGPPGMPGVPGPMGIPGEPGEEG 112 G PG+PGV G G PG GE+G Sbjct: 915 ------RGSPGIPGVKGQRGTPGAKGEQG 937 Score = 68.6 bits (166), Expect = 5e-12 Identities = 43/103 (41%), Positives = 48/103 (46%), Gaps = 16/103 (15%) Query: 31 GCYGIPGMPGLPGA-----PGKDGYDGLPGPKGEPGIPAIPGIRGP-----------KGQ 74 G G+ G PG PG G D L G KG+ G PG GP KG Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQK 117 G+PGL G PGK+G G PG GV G G PG GE+G QK Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQK 332 Score = 61.6 bits (148), Expect = 6e-10 Identities = 41/110 (37%), Positives = 47/110 (42%), Gaps = 21/110 (19%) Query: 24 LRGQ-ANTGCYGIPGMPGLPGAPGKD--GYDGLPGPKGE------PGIPAIPGIRGPKGQ 74 L+G+ + G G PG PG G PG+ G PG G G+P PG G KG Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316 Query: 75 KGEPGLPGHPGKNGPMGPPGMPGVPGPM------------GIPGEPGEEG 112 +G PGL G G G G G PG GP G PG PG G Sbjct: 317 RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRG 366 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 3/56 (5%) Query: 23 PLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP 78 P + G G PG PG G G G G PGP G G +PG++G +G G P Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG---LPGLKGKRGDSGSP 1438 Score = 34.3 bits (77), Expect = 0.10 Identities = 17/37 (45%), Positives = 19/37 (51%) Query: 34 GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRG 70 G G G PG G DG GL G +G+ G PA RG Sbjct: 1409 GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 32.3 bits (72), Expect = 0.39 Identities = 18/43 (41%), Positives = 20/43 (46%) Query: 31 GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKG 73 G G G G G PG G DGLPG KG+ G P +G Sbjct: 1403 GPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.144 0.458 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,648,959 Number of Sequences: 37866 Number of extensions: 925309 Number of successful extensions: 38845 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 284 Number of HSP's successfully gapped in prelim test: 458 Number of HSP's that attempted gapping in prelim test: 4523 Number of HSP's gapped (non-prelim): 9555 length of query: 245 length of database: 18,247,518 effective HSP length: 100 effective length of query: 145 effective length of database: 14,460,918 effective search space: 2096833110 effective search space used: 2096833110 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.