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Search of human proteins with 160707950
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo
sapiens]
(498 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] 998 0.0
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] 957 0.0
gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens] 77 3e-14
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 77 4e-14
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 74 3e-13
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 73 7e-13
gi|104526627 triadin [Homo sapiens] 67 3e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 66 6e-11
gi|32307177 forkhead box G1 [Homo sapiens] 55 1e-07
gi|188536004 zinc finger protein 469 [Homo sapiens] 55 2e-07
gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens] 55 2e-07
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 54 4e-07
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 54 4e-07
gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s... 54 4e-07
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 54 4e-07
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 54 4e-07
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo... 54 4e-07
gi|61966923 forkhead box B2 [Homo sapiens] 52 1e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 52 1e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 52 1e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 52 1e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 52 1e-06
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 52 1e-06
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 52 1e-06
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 52 1e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 52 1e-06
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 51 3e-06
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 51 3e-06
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 51 3e-06
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 51 3e-06
>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
Length = 498
Score = 998 bits (2579), Expect = 0.0
Identities = 498/498 (100%), Positives = 498/498 (100%)
Query: 1 MAAAAAAAPSGGGGGGEEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQP 60
MAAAAAAAPSGGGGGGEEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQP
Sbjct: 1 MAAAAAAAPSGGGGGGEEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQP 60
Query: 61 SAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKL 120
SAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKL
Sbjct: 61 SAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKL 120
Query: 121 KQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRR 180
KQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRR
Sbjct: 121 KQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRR 180
Query: 181 EQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQT 240
EQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQT
Sbjct: 181 EQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQT 240
Query: 241 SPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAV 300
SPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAV
Sbjct: 241 SPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAV 300
Query: 301 KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKE 360
KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKE
Sbjct: 301 KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKE 360
Query: 361 SSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDL 420
SSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDL
Sbjct: 361 SSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDL 420
Query: 421 SSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPR 480
SSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPR
Sbjct: 421 SSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPR 480
Query: 481 PNREEPVDSRTPVTERVS 498
PNREEPVDSRTPVTERVS
Sbjct: 481 PNREEPVDSRTPVTERVS 498
>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
Length = 486
Score = 957 bits (2475), Expect = 0.0
Identities = 477/477 (100%), Positives = 477/477 (100%)
Query: 22 EEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSG 81
EEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSG
Sbjct: 10 EEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSG 69
Query: 82 SAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQG 141
SAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQG
Sbjct: 70 SAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQG 129
Query: 142 KAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRG 201
KAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRG
Sbjct: 130 KAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRG 189
Query: 202 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIK 261
RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIK
Sbjct: 190 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIK 249
Query: 262 RPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTR 321
RPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTR
Sbjct: 250 RPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTR 309
Query: 322 ETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHH 381
ETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHH
Sbjct: 310 ETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHH 369
Query: 382 HHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGC 441
HHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGC
Sbjct: 370 HHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGC 429
Query: 442 PKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 498
PKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS
Sbjct: 430 PKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 486
>gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]
Length = 580
Score = 77.4 bits (189), Expect = 3e-14
Identities = 39/70 (55%), Positives = 49/70 (70%), Gaps = 1/70 (1%)
Query: 111 TLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFT 170
++P GW R +KQR G++AG++DVY I+PQG FRSK L Y K G+TSL P DFDFT
Sbjct: 85 SVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFT 144
Query: 171 V-TGRGSPSR 179
V + RG SR
Sbjct: 145 VLSKRGIKSR 154
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 77.0 bits (188), Expect = 4e-14
Identities = 111/506 (21%), Positives = 182/506 (35%), Gaps = 49/506 (9%)
Query: 15 GGEEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKA 74
GGEEE E E+ ++ K+ K KEE + E P + PAE
Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP 547
Query: 75 E--TSEGSGSAPAVPEASA-------SPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKS 125
E S A + PEA + SP + +S + + P ++ P K +
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607
Query: 126 GRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRG-SPSRREQKP 184
+ K +P + +S E+ K + + P + + SP + E K
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEV-----KSPEKAKSPTKEEAKSPEKAKSPEKEEAKS 662
Query: 185 PKKPKSP-----KAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQ 239
P+K KSP K+P + + + + K+ E + KSP K K P +
Sbjct: 663 PEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE-KAKSPVKEEAKSPEK 721
Query: 240 TSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQA-----IPKKRGRKPGSVVAAAAAE 294
K E T +K + + P+ + + P A + A+
Sbjct: 722 AKSPVKEE--AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPAD 779
Query: 295 ---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTC 351
K K+ + ++S ++ P+K+ I KE VK S + E+
Sbjct: 780 KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK----SPVKEEE------- 828
Query: 352 KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPK--APVPLLPPLPPPPPE-PESS 408
K K KE K A + PK E E+PK AP P + P E P+ S
Sbjct: 829 KPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES 888
Query: 409 EDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEP---AKTQPAVATAATAAE-KYKH 464
+ E +D E++ P ++ D PKE AK +P A A ++ K
Sbjct: 889 KVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK 948
Query: 465 RGEGERKDIVSSSMPRPNREEPVDSR 490
E+KD +P + +++
Sbjct: 949 EAAPEKKDTKEEKAKKPEEKPKTEAK 974
Score = 74.7 bits (182), Expect = 2e-13
Identities = 113/501 (22%), Positives = 197/501 (39%), Gaps = 79/501 (15%)
Query: 17 EEERLEEKSEDQDLQGLKDKPLKFKKVKKD--KKEEKEGKHEPVQPSAHHSAEPAEAGKA 74
E+ ++ EKSE + + + ++ + +V ++ ++EEKE K E + E AE G+
Sbjct: 442 EKIKVVEKSEKETV--IVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEE 499
Query: 75 ETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDV 134
ET +P EA++ K+ +S +++ + PE K+ + K
Sbjct: 500 ET-----KSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE------KEEAKSPAEVKSPE 548
Query: 135 YLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSP-KA 193
+P + +S E SP + E K P + KSP KA
Sbjct: 549 KAKSPAKEEAKSPPE------------------------AKSPEKEEAKSPAEVKSPEKA 584
Query: 194 PGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLE-KSPGKLLVKMPFQTSPGGKAEGGGAT 252
+ + + KA + + K E KSP K K P + KA+
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK----- 639
Query: 253 TSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETV 312
S K P + + E + P+K + P V A A + K K+ ++ +S ++
Sbjct: 640 -SPTKEEAKSPEKAKSPEKEEAKSPEK-AKSP--VKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 313 LPIKKR-KTRETVSIEVKEVVK-PLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSS-- 368
P+K+ K+ E VKE K P + ++ K + KSP ++ +S K +S
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755
Query: 369 ----SASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSP---------P 415
SP K S + K P P+ PE ++ P P
Sbjct: 756 AKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP 815
Query: 416 EPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVS 475
+ +++ S V KEE+ P+ ++ P + A+ + A AT T +K + E +K+
Sbjct: 816 KKEEVKSPV-KEEEKPQEVKVKE---PPKKAEEEKAPATPKTEEKKDSKKEEAPKKE--- 868
Query: 476 SSMPRPNREEPVDSRTPVTER 496
P+P EE + P E+
Sbjct: 869 --APKPKVEE---KKEPAVEK 884
Score = 52.4 bits (124), Expect = 1e-06
Identities = 98/432 (22%), Positives = 158/432 (36%), Gaps = 85/432 (19%)
Query: 19 ERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAG---KAE 75
E+ E KS ++ +K + +K K K E + + P + P +A K E
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715
Query: 76 TSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVY 135
+ V E + +P++ +S P+ ++ PE + KS A DV
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKS------PVKEEAKSPE-------KAKSPEKAKTLDVK 762
Query: 136 LINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSP-KAP 194
+P+ K +K E + +K + + SP + E K P+K KSP K
Sbjct: 763 --SPEAKT-PAKEEARSPADKFPEKA-------------KSPVKEEVKSPEKAKSPLKED 806
Query: 195 GTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTS 254
+ PK P VK E+ P ++ VK P + + KA
Sbjct: 807 AKAPEKEIPKKEEVKSP---------VKE--EEKPQEVKVKEPPKKAEEEKAPA------ 849
Query: 255 TQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAV---KESSIRSVQET 311
P + K ++ + PKK KP E K+ AV KES + + +E
Sbjct: 850 -------TPKTEEKKDSKKEEAPKKEAPKP------KVEEKKEPAVEKPKESKVEAKKEE 896
Query: 312 VLPIKKRKTRE---TVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGR--KSKESSPKGR 366
KK T E +EVKE KP + + +K K K P + + KE++P+ +
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK-AKEPSKPAEKKEAAPEKK 955
Query: 367 SSSASSPPKKEHHHHHHHSESPKAPVPLLP-----PLPPPPPEPESSEDPTSPPEPQDLS 421
+ K E E PK P P+ E +E +S +
Sbjct: 956 DTKEEKAKKPE--------EKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007
Query: 422 SSVCKEEKMPRG 433
E+K +G
Sbjct: 1008 PEKATEDKAAKG 1019
Score = 40.0 bits (92), Expect = 0.005
Identities = 50/225 (22%), Positives = 82/225 (36%), Gaps = 13/225 (5%)
Query: 273 PQAIPKKRGRKPG-SVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEV 331
P ++P+ + P S +E K K V++S +V + + T E E KE
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 332 VKPLLVSTLG---EKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESP 388
+ G E++ G + KSP + S K S K E
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA 538
Query: 389 KAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKT 448
K+P + P P E ++ P P+ +E K P ++S K PAK
Sbjct: 539 KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK------EEAKSP--AEVKSPEKAKSPAKE 590
Query: 449 QPAVATAATAAEKYKHRGEGERKDIVSSSMP-RPNREEPVDSRTP 492
+ A + EK K + E K + P + + P + ++P
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635
Score = 29.3 bits (64), Expect = 8.7
Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 7/105 (6%)
Query: 17 EEERLEEKSED-QDLQGL----KDKPLKF--KKVKKDKKEEKEGKHEPVQPSAHHSAEPA 69
+E ++E K E+ +D + + K+ P K K+ K K++ + K EP A ++PA
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA 945
Query: 70 EAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPE 114
E +A + + PK D + +P+ P+
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
sapiens]
Length = 411
Score = 73.9 bits (180), Expect = 3e-13
Identities = 53/143 (37%), Positives = 71/143 (49%), Gaps = 15/143 (10%)
Query: 79 GSGSAPA-----VPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYD 133
G G AP P SA P R + G D P LP GW ++ RKSG SAGK D
Sbjct: 117 GGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSD 176
Query: 134 VYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKA 193
VY +P GK FRSK +L Y +G+T +D + FDF TG+ PS+ ++ + P
Sbjct: 177 VYYFSPSGKKFRSKPQLARY---LGNT-VDLSSFDFR-TGKMMPSKLQKNKQRLRNDP-- 229
Query: 194 PGTGRGRGRPKGSGTTRPKAATS 216
+ +G+P TT P T+
Sbjct: 230 --LNQNKGKP-DLNTTLPIRQTA 249
>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
Length = 302
Score = 72.8 bits (177), Expect = 7e-13
Identities = 47/118 (39%), Positives = 61/118 (51%), Gaps = 10/118 (8%)
Query: 79 GSGSAPA-----VPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYD 133
G G AP P SA P R + G D P LP GW ++ RKSG SAGK D
Sbjct: 117 GGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSD 176
Query: 134 VYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSP 191
VY +P GK FRSK +L Y +G+T +D + FDF TG+ PS+ ++ + P
Sbjct: 177 VYYFSPSGKKFRSKPQLARY---LGNT-VDLSSFDFR-TGKMMPSKLQKNKQRLRNDP 229
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 67.4 bits (163), Expect = 3e-11
Identities = 112/530 (21%), Positives = 198/530 (37%), Gaps = 72/530 (13%)
Query: 17 EEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAET 76
E+E ++ ED D + + PL+ K++ KDK E++E +Q H + E GK +
Sbjct: 117 EDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEK--EKGKEKV 174
Query: 77 SEGSGSAPAVPEASASPKQR---------RSIIRDRGPMYDDPTLPEGWTRKL---KQRK 124
E PE A+ K++ +++ +++ E +++ KQ K
Sbjct: 175 RE-----KEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEK 229
Query: 125 SGRSAGKYDVYLINPQGKAFRSKVE--LIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQ 182
++A K P + E ++ E+ + D V G P +
Sbjct: 230 VKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPA 289
Query: 183 KPPKKP------KSPKAPGTGRGRGRPKGSG---TTRPKAATSEGVQVKR-------VLE 226
PP P +P +P G K + T+ K E ++ K V +
Sbjct: 290 IPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEK 349
Query: 227 KSPGKL------LVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKR 280
K PGK VK+ Q + + + + + +++P K++ + + P K
Sbjct: 350 KEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKS 409
Query: 281 GRKPGSVVAAAAAEAK-KKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVST 339
+K SV + +AK ++A +E S+++ V K+ KT +TV E+++
Sbjct: 410 PKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRK--------- 460
Query: 340 LGEKSGK--GLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPP 397
EKSGK + K P + +E P K E PK P
Sbjct: 461 --EKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKK 518
Query: 398 LPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPA-KTQPAVATAA 456
P P+ + P + Q + K EK S G P+E K AV
Sbjct: 519 EEKPEPQIKKEAKPAISEKVQIHKQDIVKPEK------TVSHGKPEEKVLKQVKAVTIEK 572
Query: 457 TAAEKYKHRGEGERKD--IVSSSMPRPNRE------EPVDSRTPVTERVS 498
TA K + E ++ + + P+P + E +T ++E+ S
Sbjct: 573 TAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKES 622
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 66.2 bits (160), Expect = 6e-11
Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 26/176 (14%)
Query: 266 KRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQ---ETVLPIKKRKTRE 322
KR+ D +P G K G VV ++++ ++K S+ ++ ET+ P R+
Sbjct: 615 KRQLSLDINKLP---GEKLGRVVHII--QSREPSLKNSNPDEIEIDFETLKPSTLRELER 669
Query: 323 TVSIEVKEVVKPLLVST---LGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPP----- 374
V+ +++ KP G KG + +S SS S + +P
Sbjct: 670 YVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKG 729
Query: 375 ------KKEHHHHHHHSESPKAPVPLLPP----LPPPPPEPESSEDPTSPPEPQDL 420
KK HHHHH + APVP PP PPPPP P+ + P PP P +
Sbjct: 730 HPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM 785
Score = 40.0 bits (92), Expect = 0.005
Identities = 89/447 (19%), Positives = 164/447 (36%), Gaps = 50/447 (11%)
Query: 17 EEERLEEKSEDQDL------------QGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHH 64
EEER + +E Q+ Q ++KP K +K KK+KK+EK + E V+ +
Sbjct: 504 EEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKS 563
Query: 65 SAEPAEAGKAETSEGSGS----APAVPEASASPKQRRSIIRDR-GPM-YDDPTLPEGWTR 118
A+ K + + S S P S P S D+ PM Y++
Sbjct: 564 KAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDIN 623
Query: 119 KLKQRKSGRSAGKYDVYLINPQGKAFRSK--VELIAYFEKVGDTSLDPNDFDFTVTGRGS 176
KL K GR V++I + + ++ E+ FE + ++L + + VT
Sbjct: 624 KLPGEKLGRV-----VHIIQSREPSLKNSNPDEIEIDFETLKPSTL--RELERYVTS--- 673
Query: 177 PSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKM 236
R+++ P+ K G+ + +G + ++++S+ E S ++ K
Sbjct: 674 -CLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDS-------EDSETEMAPKS 725
Query: 237 PFQTSPGGKAEGGGATTSTQVMVIKRPGRKR---KAEADPQAIPKKRGRKPGSVVAAAAA 293
+ PG + + Q+ P ++ + P P ++ ++P +
Sbjct: 726 KKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM 785
Query: 294 EAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKS 353
+ +SS T +P+ + + +V + +P+L E
Sbjct: 786 PQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELP-------PH 838
Query: 354 PGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPPPEPESSEDP 411
+ + S+P + A P H+ P LPP P PP P ++ P
Sbjct: 839 LPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTP 898
Query: 412 TSPPEPQDLSSSVCKEEKMPRGGSLES 438
P P V E++ P L S
Sbjct: 899 LLPQPPMAQPPQVLLEDEEPPAPPLTS 925
Score = 38.5 bits (88), Expect = 0.014
Identities = 63/290 (21%), Positives = 103/290 (35%), Gaps = 39/290 (13%)
Query: 177 PSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKL---- 232
P +++Q+PP P P P + P + P AT QV + + PG +
Sbjct: 769 PPQQQQQPPPPPPPPSMPQ----QAAPAMKSSPPPFIAT----QVPVLEPQLPGSVFDPI 820
Query: 233 ------LVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGS 286
++ +P P + +T P + A P A+ ++P
Sbjct: 821 GHFTQPILHLPQPELPPHLPQPPEHSTP--------PHLNQHAVVSPPALHNALPQQPSR 872
Query: 287 VVAAAAAEAKKKAVKESSIRSVQET-VLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 345
AAA K A + ++ +T +LP V +E +E P L S +
Sbjct: 873 PSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYL 932
Query: 346 KGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEP 405
+ L+ + P P + S PP H + + P PP PPP P+P
Sbjct: 933 QQLQKVQPP----TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP----PPPPPPQPQP 984
Query: 406 ESSEDPTSPPEPQDLS----SSVCKEEKMPRGGSLESDGCPKEPAKTQPA 451
+ PP P L S+ ++ P+G ++P QPA
Sbjct: 985 PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPA 1034
Score = 29.3 bits (64), Expect = 8.7
Identities = 24/101 (23%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 330 EVVKPLLVSTLGEKSGKGLKTCKSPG-----RKSKESSPKGRSSSASSPPKKEHHHHHHH 384
E + ++V G G+ PG ++ S+P + +PP + H
Sbjct: 167 EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP 226
Query: 385 SESPKAPV--PLLPPLPP-----PPPEPESSEDPTSP-PEP 417
+ +P V P++ +PP PPP P + P +P P+P
Sbjct: 227 AVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQP 267
Score = 29.3 bits (64), Expect = 8.7
Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 16/130 (12%)
Query: 328 VKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPK----KEHHHHHH 383
++E PL++ + + L P + + + R++S P KE H
Sbjct: 1059 LREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSP 1118
Query: 384 HSESPKAPVPLLPPLPPPPPE-PESSEDPTSPPE-----PQDLSSSVCK--EEKMPRGGS 435
S P P L P PP+ PES + P P+ P D+ V + E+ P G+
Sbjct: 1119 IIRSE----PFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGA 1174
Query: 436 LESDGCPKEP 445
+ D +EP
Sbjct: 1175 PDKDKQKQEP 1184
Score = 29.3 bits (64), Expect = 8.7
Identities = 38/153 (24%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Query: 176 SPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE-GVQVKRVLEKSPGKLLV 234
SPS R + PPK P+S KAP R K RP E +K K
Sbjct: 1126 SPSLRPE-PPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEP 1184
Query: 235 KMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP-----QAIPKKRGRKPGSVVA 289
K P K + G+ S P K+ +D +A +K R+
Sbjct: 1185 KTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQ 1244
Query: 290 AAAAEAKKKAVKESSIRSVQETVLPIKKRKTRE 322
A AE +K+ +++ +RS ++ + R+ E
Sbjct: 1245 AEHAEKEKERLRQERMRSREDEDALEQARRAHE 1277
>gi|32307177 forkhead box G1 [Homo sapiens]
Length = 489
Score = 55.1 bits (131), Expect = 1e-07
Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 24/119 (20%)
Query: 373 PPKKEHHHHHHHSESPKAPVPLLPPL-----PPPPPEPESSED----------------- 410
P HHHHHHH P AP P PP PPPPP P+ +
Sbjct: 45 PQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLL 104
Query: 411 PTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGE 469
P PP P + K + + GG E G P E A P A + +G GE
Sbjct: 105 PPPPPPPPAAALDGAKADGL--GGKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGE 161
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 11/102 (10%)
Query: 370 ASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPP----EPQDLSSSVC 425
AS HH HHH P PP P PPP P+ + P PP PQ +
Sbjct: 35 ASHGHHNSHHPQHHHHHHHHHHHP-PPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAA 93
Query: 426 KEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGE 467
++K P+ L P PA A A+ +GE
Sbjct: 94 DDDKGPQQLLL------PPPPPPPPAAALDGAKADGLGGKGE 129
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 54.7 bits (130), Expect = 2e-07
Identities = 114/488 (23%), Positives = 160/488 (32%), Gaps = 140/488 (28%)
Query: 3 AAAAAAPSGGGGGGEEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSA 62
+ AA SG GGGG L + D GL ++P P +P
Sbjct: 960 SGGAAEGSGSGGGGRASGLRPRRND----GLGERP-------------------PPRPRR 996
Query: 63 HHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQ 122
+ P + AP VP A+A P++ RS R R P DP RK K
Sbjct: 997 PRTQAPGSR--------ADPAPRVPRAAALPEETRSSRRRRLPPRKDP-------RKRKA 1041
Query: 123 RKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQ 182
R G + GK + I Q R ++DF S S ++
Sbjct: 1042 R--GGAWGKELILKIVQQKNRLR--------------------EYDF-----ASESEEDE 1074
Query: 183 KPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSP 242
+PP P+ PG RGR +G G R + ++G + E P K + +
Sbjct: 1075 QPP-----PRGPGF-RGR---RGRGEKRKEVELTQGPR-----EDEPQKP------RKAA 1114
Query: 243 GGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKE 302
+A G GA + + RPG P P+ RG AAA E K
Sbjct: 1115 RQEAGGDGAPANPEEPGGSRPG--------PGRSPQARGPSRSLETGAAAREGGPKCADR 1166
Query: 303 SSIRSVQETVLPIKKRKTRET---------------------VSIEVKEVVKPLLVSTLG 341
S+ +P + ET S E E ++ + G
Sbjct: 1167 PSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAG 1226
Query: 342 EKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESP------------- 388
E SPG E P R + + P + H SP
Sbjct: 1227 EMGA-------SPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGG 1279
Query: 389 -KAPVPLLPPLPP--PPPE---PESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCP 442
+APV PP P E P ++ T+ P+P LSS + P G + + G P
Sbjct: 1280 TQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVP 1339
Query: 443 KEPAKTQP 450
QP
Sbjct: 1340 VAKKGPQP 1347
Score = 32.0 bits (71), Expect = 1.3
Identities = 71/305 (23%), Positives = 96/305 (31%), Gaps = 64/305 (20%)
Query: 176 SPSRREQKP--PKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLL 233
+PS+ + P P+K APG RG G PKA Q SP
Sbjct: 3660 TPSKALKFPVHPRKAVGSLAPGE-LARGTENGMKPATPKAKPGPSSQGSG----SP---- 3710
Query: 234 VKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAA 293
PG K GG G+ + A A P R P A A
Sbjct: 3711 -------RPGTKTGGGSQPQPAS-------GQLQSETATTPAKPSFPSRSPAPERLPARA 3756
Query: 294 EAKK--KAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTC 351
+AK K +E+ + ++ P +K GE S K K
Sbjct: 3757 QAKSCTKGPREAGEQGPHGSLGPKEK-----------------------GESSTKRKKGQ 3793
Query: 352 KSPGRKSKESSPKGRSSSA-SSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSED 410
+S+ GR+ SA PP+ P P P P PPP + +
Sbjct: 3794 VPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAE 3853
Query: 411 PTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGER 470
P L + P+G L P K AV A AE + HR +
Sbjct: 3854 PGHTQRKDRLGKA------FPQGRPL------LRPPKRGTAV-HGAEPAEPHTHRTAEAQ 3900
Query: 471 KDIVS 475
D++S
Sbjct: 3901 SDLLS 3905
Score = 31.2 bits (69), Expect = 2.3
Identities = 57/281 (20%), Positives = 99/281 (35%), Gaps = 37/281 (13%)
Query: 49 EEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYD 108
++ EGK P+ S A P G+ E S S RG +
Sbjct: 3581 QDAEGKRAPLVFSGKRRA-PGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHK 3639
Query: 109 -DPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167
T P G K R + + K + ++P+ + VG SL P +
Sbjct: 3640 GSATKPAGCQSSSKDRSAASTPSKALKFPVHPR--------------KAVG--SLAPGEL 3683
Query: 168 DFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEK 227
RG+ + + PK P + G+G R K G ++P+ A+ + +Q +
Sbjct: 3684 -----ARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQ-LQSETATTP 3737
Query: 228 SPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRP----GRKRKAEADPQAIPKKRGRK 283
+ + P +A+ T + + P G K K E+ + +K+G+
Sbjct: 3738 AKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTK---RKKGQV 3794
Query: 284 PGSVVAAA------AAEAKKKAVKESSIRSVQETVLPIKKR 318
PG + + A A K + ++ VLP K +
Sbjct: 3795 PGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPK 3835
>gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]
Length = 291
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/63 (44%), Positives = 38/63 (60%), Gaps = 4/63 (6%)
Query: 107 YDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPND 166
++ P LP+GW R+ R+SG SAG DV+ +P GK FRSK +L Y S+D +
Sbjct: 6 WECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYL----GGSMDLST 61
Query: 167 FDF 169
FDF
Sbjct: 62 FDF 64
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 53.5 bits (127), Expect = 4e-07
Identities = 118/539 (21%), Positives = 184/539 (34%), Gaps = 101/539 (18%)
Query: 17 EEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAET 76
E++ SED D + +KP + EPV SAH S+ +E+ T
Sbjct: 424 EDDLQLSDSEDSDSEQTPEKPPS----SSAPPSAPQSLPEPVA-SAHSSSAESES----T 474
Query: 77 SEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLP----EGWTRKLKQRKSGRSAGKY 132
S+ S+ + E+S+S + + P + PT + W K+ Q + +
Sbjct: 475 SDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR- 533
Query: 133 DVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPK 192
P + SK + + S DP P + K P+ P P+
Sbjct: 534 ---STEPPRRHPESKGSSDSATSQEHSESKDP------------PPKSSSKAPRAP--PE 576
Query: 193 APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAE----- 247
AP G+ R K P + G + K P K + +TS G+ E
Sbjct: 577 APHPGK-RSCQKSPAQQEPPQRQTVGTK----QPKKPVKASARAGSRTSLQGEREPGLLP 631
Query: 248 -GGGATTSTQVMVIKRPGRKRKA---EADPQAIPKKRGRK-----PGSVVAAAAAEAKKK 298
G TS +K GR R A E P P +K P A + E K
Sbjct: 632 YGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKD 691
Query: 299 AVKESSIRSV------------------------QETVLPIKKRKTRETVSIEVKEVVKP 334
V++ + Q V+ RK R + + +++ P
Sbjct: 692 NVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSP 751
Query: 335 L----------------LVSTLGEKSGKGLKTCKS----PGRKSKESSPKGRSSSASSPP 374
L L+S + + GKG + K+ P K SS K S S+S
Sbjct: 752 LRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLA 811
Query: 375 KKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGG 434
KK ++ K + L + SS +S +P SS K+E +P
Sbjct: 812 KKRKGEAERDCDNKK--IRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPP 869
Query: 435 SLESDGCPKEPA--KTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRT 491
S P +PA +++ T K + KD SS+P+ R E SR+
Sbjct: 870 VSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKD---SSIPKQRRVEGKGSRS 925
Score = 34.7 bits (78), Expect = 0.21
Identities = 89/416 (21%), Positives = 139/416 (33%), Gaps = 73/416 (17%)
Query: 2 AAAAAAAPSGGGGGGEEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPS 61
A+A A + + G E L S DQ KDKP KVK + +EP
Sbjct: 611 ASARAGSRTSLQGEREPGLLPYGSRDQTS---KDKP----KVKTKGRPRAAASNEP---- 659
Query: 62 AHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLK 121
+PA +E + S PA +A + P+ + + DR P + +P ++
Sbjct: 660 -----KPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEH-FALVPLTESQGPP 713
Query: 122 QRKSG-RSAGKYDVYLINPQGKAFRSKVEL--IAYFEKVGDTSLDPNDFDFTVTGRGSPS 178
SG R++G ++ + R + L + DT P +T S
Sbjct: 714 HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTP-PPQSLMVKIT-LDLLS 771
Query: 179 RREQKPPKKPKSPKA----PGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLV 234
R Q P K + KA P G+ K S + K A + +R + +L
Sbjct: 772 RIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEK 831
Query: 235 KMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAE 294
++ Q+S + + T +P R + + +P P V +++
Sbjct: 832 EIKSQSSSSSSSHKESSKT--------KPSRPSSQSSKKEMLP------PPPVSSSSQKP 877
Query: 295 AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSP 354
AK P KR RE T G+ K + KS
Sbjct: 878 AK-----------------PALKRSRRE--------------ADTCGQDPPKSASSTKSN 906
Query: 355 GRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSED 410
+ S S PK R H + PVP LP P +P+ D
Sbjct: 907 HKDS--SIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFD 960
Score = 31.6 bits (70), Expect = 1.7
Identities = 36/164 (21%), Positives = 59/164 (35%), Gaps = 21/164 (12%)
Query: 342 EKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPP 401
E G +SK+ PK S + +PP+ H +SP PP
Sbjct: 543 ESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQ-------EPP 595
Query: 402 PPEPESSEDPTSPPEPQDLSSSVC-----KEEKMPRGGSLESDGCPKEPAKTQPAVATAA 456
+ ++ P P + + S +E + GS + K KT+ AA
Sbjct: 596 QRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAA 655
Query: 457 TAAEKYKHRGEGERKDIVSSSMPRPNR--------EEPVDSRTP 492
+ K E+K SS+P P++ ++ V+ RTP
Sbjct: 656 SNEPKPAVPPSSEKKK-HKSSLPAPSKALSGPEPAKDNVEDRTP 698
Score = 31.2 bits (69), Expect = 2.3
Identities = 36/161 (22%), Positives = 57/161 (35%), Gaps = 21/161 (13%)
Query: 353 SPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPL-------------- 398
S +S+ +S SS + S + E+P AP P P
Sbjct: 466 SSSAESESTSDSDSSSDSESESSSSDSEENEPLETP-APEPEPPTTNKWQLDNWLTKVSQ 524
Query: 399 PPPPPE-PESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAAT 457
P PPE P S+E P PE + S S +E S D PK +K A A
Sbjct: 525 PAAPPEGPRSTEPPRRHPESKGSSDSATSQEH-----SESKDPPPKSSSKAPRAPPEAPH 579
Query: 458 AAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 498
++ + +++ ++ ++PV + R S
Sbjct: 580 PGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS 620
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
sapiens]
Length = 503
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
sapiens]
Length = 549
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|61966923 forkhead box B2 [Homo sapiens]
Length = 432
Score = 52.4 bits (124), Expect = 1e-06
Identities = 32/85 (37%), Positives = 38/85 (44%), Gaps = 14/85 (16%)
Query: 378 HHHHHHHSESPKAPVPLLPPLPPPPPEPE---SSEDPTSPPEPQDLSSSVCKEEKMPRGG 434
HHHHHHH P PP PPPPP + PT+P P L S ++ P+
Sbjct: 155 HHHHHHHPPQPP------PPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQ--PPQQPPQQS 206
Query: 435 SLESDGCPKEPAKTQPAVATAATAA 459
+ P P K Q A A AA AA
Sbjct: 207 QPQQ---PSHPGKMQEAAAVAAAAA 228
Score = 37.7 bits (86), Expect = 0.024
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 7/99 (7%)
Query: 373 PPKKEHHHHHHHSESPKAPVPL--LPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKM 430
PP H H+ H + P AP P LP PP P +S S P +++V
Sbjct: 170 PPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQQPPQQSQPQQPSHPGKMQEAAAVAAAAAA 229
Query: 431 PRGGSLESDG-----CPKEPAKTQPAVATAATAAEKYKH 464
++ S G P A A AA + +KH
Sbjct: 230 AAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTSGFKH 268
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/309 (22%), Positives = 109/309 (35%), Gaps = 30/309 (9%)
Query: 160 TSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAAT-SEG 218
T P T + +P+ E+ P P+ P P T P+ T PKAA +
Sbjct: 491 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-TPTT------PEEPAPTTPKAAAPNTP 543
Query: 219 VQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPK 278
+ K P K P T+P K T +K P + P+ +
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTP--KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601
Query: 279 KRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVS 338
++P S A K ++ + T K T +K +
Sbjct: 602 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT---PKEPAPTTPKGTAPTTLKEPAPT 658
Query: 339 TLGEKSGKGLKTCKSPGRKSKES---SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 395
T + + K L + G S S +P +A + PK+ +PK P P
Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPTT 712
Query: 396 PPLPPPPPE----PESSEDPTSPPEPQDLSSSVCKEEKMPRG--GSLESDGCP--KEPAK 447
P PPP P ++++PT+ + D S+ E P+ S + G P K PA
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 772
Query: 448 TQPAVATAA 456
T+P + T A
Sbjct: 773 TKPEMTTTA 781
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/298 (25%), Positives = 96/298 (32%), Gaps = 35/298 (11%)
Query: 172 TGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 231
T + +P+ ++ P PK P AP T PK T PK T + K P
Sbjct: 290 TTKSAPTTPKEPAPTTPKKP-APTT------PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342
Query: 232 LLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP----QAIPKKRGRKPGSV 287
K P T+P K K P E P + P P +
Sbjct: 343 TTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400
Query: 288 VAAAAAEAKKKAV--KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 345
A K KE S + +E K T K +T E +
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 346 KGLKTCKSPGRKS-KESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPP 402
T K P + KE +P +A + PKK +P P L P P P P
Sbjct: 461 T---TTKKPAPTTPKEPAPTTPKETAPTTPKKL---------TPTTPEKLAPTTPEKPAP 508
Query: 403 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAE 460
PE PT+P EP + EE P + PKEPA T P T E
Sbjct: 509 TTPEELA-PTTPEEP----TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Score = 50.4 bits (119), Expect = 4e-06
Identities = 106/483 (21%), Positives = 153/483 (31%), Gaps = 60/483 (12%)
Query: 42 KVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIR 101
+VK +KK + K P P + + G + + S + S SPK I
Sbjct: 65 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK-----IT 119
Query: 102 DRGPMYDDPTLPEGWTRKLKQR---KSGRSAGKYDVYLINPQ----GKAFRSKVELIAYF 154
P+ P+LP + + + N Q GK + +
Sbjct: 120 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 179
Query: 155 EKVGDTSLDPND---------FDFTVTGRGSPSRREQKP--PKKPKS--PKAPGTGRGRG 201
EK L P + T G + +E P PK+P S PK P +
Sbjct: 180 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 239
Query: 202 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKA-----EGGGATTSTQ 256
P T PK + K P K P T+P A E TT +
Sbjct: 240 AP-----TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294
Query: 257 VMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIK 316
K P + P PK+ + KE + + +E
Sbjct: 295 PTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353
Query: 317 KRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLK-----TCKSPGRKSKESSPKGRSSSAS 371
K+ T K +T E S K T KS +KE +P S+ +
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 372 SPPKKEHHHHHHHSESPKAPVPLLP--PLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK 429
+P + + K P P P P P P +P PT+P EP + +E
Sbjct: 414 TPKEPS-------PTTTKEPAPTTPKEPAPTTPKKPA----PTTPKEP----APTTPKEP 458
Query: 430 MPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 489
P + PKEPA T P TA T +K E+ + P P E +
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAP 516
Query: 490 RTP 492
TP
Sbjct: 517 TTP 519
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 309 QETVLPIKKRKTRETVSIEVKEVVKP-LLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRS 367
+ET L + K T +E KE ST G++ K +S + S +
Sbjct: 138 KETSLTVNKETT-----VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192
Query: 368 SSASSPPKKEHHHHHHHSESPKAPVPLLPPLP----PPPPEPESSED-PTSPPEPQDL-- 420
A PK E +PK P P P P P P P + + PT+P EP
Sbjct: 193 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 252
Query: 421 -SSSVCKEEKMPRGGSLESDGCPKEPAKT---QPAVATAATAAEKYKHRGEGERKDIVSS 476
S+ +E P + PKEPA T +PA T +A K K +
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312
Query: 477 SMPRPNREEPVDSRTPVTER 496
+ P P + TP T +
Sbjct: 313 TPKEPAPTTPKEP-TPTTPK 331
Score = 38.9 bits (89), Expect = 0.011
Identities = 70/306 (22%), Positives = 111/306 (36%), Gaps = 38/306 (12%)
Query: 176 SPSRREQKPPKKPKSPK----APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 231
+P+ ++ P PK P AP T +G + TT K A + + K P
Sbjct: 648 APTTLKEPAPTTPKKPAPKELAPTTTKGP-----TSTTSDKPAPTTPKETAPTTPKEPAP 702
Query: 232 LLVKMPF----QTSPGGKAEGGGATTSTQVMVI-KRPGRKR---KAEADPQAI---PKKR 280
K P +T P +E TT+ + I K P AE P+A+ PK+
Sbjct: 703 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762
Query: 281 GRKPGSVVAAAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV 337
G AA E K E +R+ ET K T+ET + K +
Sbjct: 763 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM-TKETATTTEKTTESKITA 821
Query: 338 STLGEKSGKGLKTC--KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 395
+T S T K K+ +PK +++ + E + + PK
Sbjct: 822 TTTQVTSTTTQDTTPFKITTLKTTTLAPKV-TTTKKTITTTEIMNKPEETAKPKDRATNS 880
Query: 396 PPLPPPPPEP-ESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVAT 454
P P +P ++ + PTS +P + MPR ++ P++ T P +
Sbjct: 881 KATTPKPQKPTKAPKKPTSTKKP----------KTMPRVRKPKTTPTPRKMTSTMPELNP 930
Query: 455 AATAAE 460
+ AE
Sbjct: 931 TSRIAE 936
Score = 29.3 bits (64), Expect = 8.7
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 179 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQ-VKRVLE----------K 227
++ K PKKP S K P T +PK + T R +T + R+ E +
Sbjct: 888 QKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 947
Query: 228 SPGKLLVKMPFQTSPGGKAEG 248
+P LV++ ++ G AEG
Sbjct: 948 TPNSKLVEVNPKSEDAGGAEG 968
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/309 (22%), Positives = 109/309 (35%), Gaps = 30/309 (9%)
Query: 160 TSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAAT-SEG 218
T P T + +P+ E+ P P+ P P T P+ T PKAA +
Sbjct: 532 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-TPTT------PEEPAPTTPKAAAPNTP 584
Query: 219 VQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPK 278
+ K P K P T+P K T +K P + P+ +
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTP--KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642
Query: 279 KRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVS 338
++P S A K ++ + T K T +K +
Sbjct: 643 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT---PKEPAPTTPKGTAPTTLKEPAPT 699
Query: 339 TLGEKSGKGLKTCKSPGRKSKES---SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 395
T + + K L + G S S +P +A + PK+ +PK P P
Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPTT 753
Query: 396 PPLPPPPPE----PESSEDPTSPPEPQDLSSSVCKEEKMPRG--GSLESDGCP--KEPAK 447
P PPP P ++++PT+ + D S+ E P+ S + G P K PA
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 813
Query: 448 TQPAVATAA 456
T+P + T A
Sbjct: 814 TKPEMTTTA 822
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/298 (25%), Positives = 96/298 (32%), Gaps = 35/298 (11%)
Query: 172 TGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 231
T + +P+ ++ P PK P AP T PK T PK T + K P
Sbjct: 331 TTKSAPTTPKEPAPTTPKKP-APTT------PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383
Query: 232 LLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP----QAIPKKRGRKPGSV 287
K P T+P K K P E P + P P +
Sbjct: 384 TTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441
Query: 288 VAAAAAEAKKKAV--KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 345
A K KE S + +E K T K +T E +
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 346 KGLKTCKSPGRKS-KESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPP 402
T K P + KE +P +A + PKK +P P L P P P P
Sbjct: 502 T---TTKKPAPTTPKEPAPTTPKETAPTTPKKL---------TPTTPEKLAPTTPEKPAP 549
Query: 403 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAE 460
PE PT+P EP + EE P + PKEPA T P T E
Sbjct: 550 TTPEELA-PTTPEEP----TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Score = 50.4 bits (119), Expect = 4e-06
Identities = 106/483 (21%), Positives = 153/483 (31%), Gaps = 60/483 (12%)
Query: 42 KVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIR 101
+VK +KK + K P P + + G + + S + S SPK I
Sbjct: 106 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK-----IT 160
Query: 102 DRGPMYDDPTLPEGWTRKLKQR---KSGRSAGKYDVYLINPQ----GKAFRSKVELIAYF 154
P+ P+LP + + + N Q GK + +
Sbjct: 161 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 220
Query: 155 EKVGDTSLDPND---------FDFTVTGRGSPSRREQKP--PKKPKS--PKAPGTGRGRG 201
EK L P + T G + +E P PK+P S PK P +
Sbjct: 221 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 280
Query: 202 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKA-----EGGGATTSTQ 256
P T PK + K P K P T+P A E TT +
Sbjct: 281 AP-----TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335
Query: 257 VMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIK 316
K P + P PK+ + KE + + +E
Sbjct: 336 PTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394
Query: 317 KRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLK-----TCKSPGRKSKESSPKGRSSSAS 371
K+ T K +T E S K T KS +KE +P S+ +
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 372 SPPKKEHHHHHHHSESPKAPVPLLP--PLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK 429
+P + + K P P P P P P +P PT+P EP + +E
Sbjct: 455 TPKEPS-------PTTTKEPAPTTPKEPAPTTPKKPA----PTTPKEP----APTTPKEP 499
Query: 430 MPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 489
P + PKEPA T P TA T +K E+ + P P E +
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAP 557
Query: 490 RTP 492
TP
Sbjct: 558 TTP 560
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 309 QETVLPIKKRKTRETVSIEVKEVVKP-LLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRS 367
+ET L + K T +E KE ST G++ K +S + S +
Sbjct: 179 KETSLTVNKETT-----VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233
Query: 368 SSASSPPKKEHHHHHHHSESPKAPVPLLPPLP----PPPPEPESSED-PTSPPEPQDL-- 420
A PK E +PK P P P P P P P + + PT+P EP
Sbjct: 234 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 293
Query: 421 -SSSVCKEEKMPRGGSLESDGCPKEPAKT---QPAVATAATAAEKYKHRGEGERKDIVSS 476
S+ +E P + PKEPA T +PA T +A K K +
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353
Query: 477 SMPRPNREEPVDSRTPVTER 496
+ P P + TP T +
Sbjct: 354 TPKEPAPTTPKEP-TPTTPK 372
Score = 38.9 bits (89), Expect = 0.011
Identities = 70/306 (22%), Positives = 111/306 (36%), Gaps = 38/306 (12%)
Query: 176 SPSRREQKPPKKPKSPK----APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 231
+P+ ++ P PK P AP T +G + TT K A + + K P
Sbjct: 689 APTTLKEPAPTTPKKPAPKELAPTTTKGP-----TSTTSDKPAPTTPKETAPTTPKEPAP 743
Query: 232 LLVKMPF----QTSPGGKAEGGGATTSTQVMVI-KRPGRKR---KAEADPQAI---PKKR 280
K P +T P +E TT+ + I K P AE P+A+ PK+
Sbjct: 744 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803
Query: 281 GRKPGSVVAAAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV 337
G AA E K E +R+ ET K T+ET + K +
Sbjct: 804 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM-TKETATTTEKTTESKITA 862
Query: 338 STLGEKSGKGLKTC--KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 395
+T S T K K+ +PK +++ + E + + PK
Sbjct: 863 TTTQVTSTTTQDTTPFKITTLKTTTLAPKV-TTTKKTITTTEIMNKPEETAKPKDRATNS 921
Query: 396 PPLPPPPPEP-ESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVAT 454
P P +P ++ + PTS +P + MPR ++ P++ T P +
Sbjct: 922 KATTPKPQKPTKAPKKPTSTKKP----------KTMPRVRKPKTTPTPRKMTSTMPELNP 971
Query: 455 AATAAE 460
+ AE
Sbjct: 972 TSRIAE 977
Score = 29.3 bits (64), Expect = 8.7
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 179 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQ-VKRVLE----------K 227
++ K PKKP S K P T +PK + T R +T + R+ E +
Sbjct: 929 QKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 988
Query: 228 SPGKLLVKMPFQTSPGGKAEG 248
+P LV++ ++ G AEG
Sbjct: 989 TPNSKLVEVNPKSEDAGGAEG 1009
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 52.0 bits (123), Expect = 1e-06
Identities = 107/483 (22%), Positives = 153/483 (31%), Gaps = 60/483 (12%)
Query: 42 KVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIR 101
KVK +KK + K P P + + G + + S + S SPK I
Sbjct: 158 KVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK-----IT 212
Query: 102 DRGPMYDDPTLPEGWTRKLKQR---KSGRSAGKYDVYLINPQ----GKAFRSKVELIAYF 154
P+ P+LP + + + N Q GK + +
Sbjct: 213 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 272
Query: 155 EKVGDTSLDPND---------FDFTVTGRGSPSRREQKP--PKKPKS--PKAPGTGRGRG 201
EK L P + T G + +E P PK+P S PK P +
Sbjct: 273 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 332
Query: 202 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKA-----EGGGATTSTQ 256
P T PK + K P K P T+P A E TT +
Sbjct: 333 AP-----TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387
Query: 257 VMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIK 316
K P + P PK+ + KE + + +E
Sbjct: 388 PTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446
Query: 317 KRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLK-----TCKSPGRKSKESSPKGRSSSAS 371
K+ T K +T E S K T KS +KE +P S+ +
Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506
Query: 372 SPPKKEHHHHHHHSESPKAPVPLLP--PLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK 429
+P + + K P P P P P P +P PT+P EP + +E
Sbjct: 507 TPKEPS-------PTTTKEPAPTTPKEPAPTTPKKPA----PTTPKEP----APTTPKEP 551
Query: 430 MPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 489
P + PKEPA T P TA T +K E+ + P P E +
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAP 609
Query: 490 RTP 492
TP
Sbjct: 610 TTP 612
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/309 (22%), Positives = 109/309 (35%), Gaps = 30/309 (9%)
Query: 160 TSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAAT-SEG 218
T P T + +P+ E+ P P+ P P T P+ T PKAA +
Sbjct: 584 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-TPTT------PEEPAPTTPKAAAPNTP 636
Query: 219 VQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPK 278
+ K P K P T+P K T +K P + P+ +
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTP--KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694
Query: 279 KRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVS 338
++P S A K ++ + T K T +K +
Sbjct: 695 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT---PKEPAPTTPKGTAPTTLKEPAPT 751
Query: 339 TLGEKSGKGLKTCKSPGRKSKES---SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 395
T + + K L + G S S +P +A + PK+ +PK P P
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPTT 805
Query: 396 PPLPPPPPE----PESSEDPTSPPEPQDLSSSVCKEEKMPRG--GSLESDGCP--KEPAK 447
P PPP P ++++PT+ + D S+ E P+ S + G P K PA
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865
Query: 448 TQPAVATAA 456
T+P + T A
Sbjct: 866 TKPEMTTTA 874
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/298 (25%), Positives = 96/298 (32%), Gaps = 35/298 (11%)
Query: 172 TGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 231
T + +P+ ++ P PK P AP T PK T PK T + K P
Sbjct: 383 TTKSAPTTPKEPAPTTPKKP-APTT------PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435
Query: 232 LLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP----QAIPKKRGRKPGSV 287
K P T+P K K P E P + P P +
Sbjct: 436 TTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 288 VAAAAAEAKKKAV--KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 345
A K KE S + +E K T K +T E +
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 346 KGLKTCKSPGRKS-KESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPP 402
T K P + KE +P +A + PKK +P P L P P P P
Sbjct: 554 T---TTKKPAPTTPKEPAPTTPKETAPTTPKKL---------TPTTPEKLAPTTPEKPAP 601
Query: 403 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAE 460
PE PT+P EP + EE P + PKEPA T P T E
Sbjct: 602 TTPEELA-PTTPEEP----TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 309 QETVLPIKKRKTRETVSIEVKEVVKP-LLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRS 367
+ET L + K T +E KE ST G++ K +S + S +
Sbjct: 231 KETSLTVNKETT-----VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 285
Query: 368 SSASSPPKKEHHHHHHHSESPKAPVPLLPPLP----PPPPEPESSED-PTSPPEPQDL-- 420
A PK E +PK P P P P P P P + + PT+P EP
Sbjct: 286 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 345
Query: 421 -SSSVCKEEKMPRGGSLESDGCPKEPAKT---QPAVATAATAAEKYKHRGEGERKDIVSS 476
S+ +E P + PKEPA T +PA T +A K K +
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 477 SMPRPNREEPVDSRTPVTER 496
+ P P + TP T +
Sbjct: 406 TPKEPAPTTPKEP-TPTTPK 424
Score = 38.9 bits (89), Expect = 0.011
Identities = 70/306 (22%), Positives = 111/306 (36%), Gaps = 38/306 (12%)
Query: 176 SPSRREQKPPKKPKSPK----APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 231
+P+ ++ P PK P AP T +G + TT K A + + K P
Sbjct: 741 APTTLKEPAPTTPKKPAPKELAPTTTKGP-----TSTTSDKPAPTTPKETAPTTPKEPAP 795
Query: 232 LLVKMPF----QTSPGGKAEGGGATTSTQVMVI-KRPGRKR---KAEADPQAI---PKKR 280
K P +T P +E TT+ + I K P AE P+A+ PK+
Sbjct: 796 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
Query: 281 GRKPGSVVAAAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV 337
G AA E K E +R+ ET K T+ET + K +
Sbjct: 856 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM-TKETATTTEKTTESKITA 914
Query: 338 STLGEKSGKGLKTC--KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 395
+T S T K K+ +PK +++ + E + + PK
Sbjct: 915 TTTQVTSTTTQDTTPFKITTLKTTTLAPKV-TTTKKTITTTEIMNKPEETAKPKDRATNS 973
Query: 396 PPLPPPPPEP-ESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVAT 454
P P +P ++ + PTS +P + MPR ++ P++ T P +
Sbjct: 974 KATTPKPQKPTKAPKKPTSTKKP----------KTMPRVRKPKTTPTPRKMTSTMPELNP 1023
Query: 455 AATAAE 460
+ AE
Sbjct: 1024 TSRIAE 1029
Score = 29.3 bits (64), Expect = 8.7
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 179 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQ-VKRVLE----------K 227
++ K PKKP S K P T +PK + T R +T + R+ E +
Sbjct: 981 QKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 1040
Query: 228 SPGKLLVKMPFQTSPGGKAEG 248
+P LV++ ++ G AEG
Sbjct: 1041 TPNSKLVEVNPKSEDAGGAEG 1061
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 52.0 bits (123), Expect = 1e-06
Identities = 107/483 (22%), Positives = 153/483 (31%), Gaps = 60/483 (12%)
Query: 42 KVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIR 101
KVK +KK + K P P + + G + + S + S SPK I
Sbjct: 199 KVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK-----IT 253
Query: 102 DRGPMYDDPTLPEGWTRKLKQR---KSGRSAGKYDVYLINPQ----GKAFRSKVELIAYF 154
P+ P+LP + + + N Q GK + +
Sbjct: 254 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 313
Query: 155 EKVGDTSLDPND---------FDFTVTGRGSPSRREQKP--PKKPKS--PKAPGTGRGRG 201
EK L P + T G + +E P PK+P S PK P +
Sbjct: 314 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 373
Query: 202 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKA-----EGGGATTSTQ 256
P T PK + K P K P T+P A E TT +
Sbjct: 374 AP-----TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428
Query: 257 VMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIK 316
K P + P PK+ + KE + + +E
Sbjct: 429 PTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 487
Query: 317 KRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLK-----TCKSPGRKSKESSPKGRSSSAS 371
K+ T K +T E S K T KS +KE +P S+ +
Sbjct: 488 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547
Query: 372 SPPKKEHHHHHHHSESPKAPVPLLP--PLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK 429
+P + + K P P P P P P +P PT+P EP + +E
Sbjct: 548 TPKEPS-------PTTTKEPAPTTPKEPAPTTPKKPA----PTTPKEP----APTTPKEP 592
Query: 430 MPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 489
P + PKEPA T P TA T +K E+ + P P E +
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAP 650
Query: 490 RTP 492
TP
Sbjct: 651 TTP 653
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/309 (22%), Positives = 109/309 (35%), Gaps = 30/309 (9%)
Query: 160 TSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAAT-SEG 218
T P T + +P+ E+ P P+ P P T P+ T PKAA +
Sbjct: 625 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-TPTT------PEEPAPTTPKAAAPNTP 677
Query: 219 VQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPK 278
+ K P K P T+P K T +K P + P+ +
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTP--KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 279 KRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVS 338
++P S A K ++ + T K T +K +
Sbjct: 736 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT---PKEPAPTTPKGTAPTTLKEPAPT 792
Query: 339 TLGEKSGKGLKTCKSPGRKSKES---SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 395
T + + K L + G S S +P +A + PK+ +PK P P
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPTT 846
Query: 396 PPLPPPPPE----PESSEDPTSPPEPQDLSSSVCKEEKMPRG--GSLESDGCP--KEPAK 447
P PPP P ++++PT+ + D S+ E P+ S + G P K PA
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906
Query: 448 TQPAVATAA 456
T+P + T A
Sbjct: 907 TKPEMTTTA 915
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/298 (25%), Positives = 96/298 (32%), Gaps = 35/298 (11%)
Query: 172 TGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 231
T + +P+ ++ P PK P AP T PK T PK T + K P
Sbjct: 424 TTKSAPTTPKEPAPTTPKKP-APTT------PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476
Query: 232 LLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP----QAIPKKRGRKPGSV 287
K P T+P K K P E P + P P +
Sbjct: 477 TTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 288 VAAAAAEAKKKAV--KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 345
A K KE S + +E K T K +T E +
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 346 KGLKTCKSPGRKS-KESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPP 402
T K P + KE +P +A + PKK +P P L P P P P
Sbjct: 595 T---TTKKPAPTTPKEPAPTTPKETAPTTPKKL---------TPTTPEKLAPTTPEKPAP 642
Query: 403 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAE 460
PE PT+P EP + EE P + PKEPA T P T E
Sbjct: 643 TTPEELA-PTTPEEP----TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 309 QETVLPIKKRKTRETVSIEVKEVVKP-LLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRS 367
+ET L + K T +E KE ST G++ K +S + S +
Sbjct: 272 KETSLTVNKETT-----VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 326
Query: 368 SSASSPPKKEHHHHHHHSESPKAPVPLLPPLP----PPPPEPESSED-PTSPPEPQDL-- 420
A PK E +PK P P P P P P P + + PT+P EP
Sbjct: 327 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 386
Query: 421 -SSSVCKEEKMPRGGSLESDGCPKEPAKT---QPAVATAATAAEKYKHRGEGERKDIVSS 476
S+ +E P + PKEPA T +PA T +A K K +
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 477 SMPRPNREEPVDSRTPVTER 496
+ P P + TP T +
Sbjct: 447 TPKEPAPTTPKEP-TPTTPK 465
Score = 38.9 bits (89), Expect = 0.011
Identities = 70/306 (22%), Positives = 111/306 (36%), Gaps = 38/306 (12%)
Query: 176 SPSRREQKPPKKPKSPK----APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 231
+P+ ++ P PK P AP T +G + TT K A + + K P
Sbjct: 782 APTTLKEPAPTTPKKPAPKELAPTTTKGP-----TSTTSDKPAPTTPKETAPTTPKEPAP 836
Query: 232 LLVKMPF----QTSPGGKAEGGGATTSTQVMVI-KRPGRKR---KAEADPQAI---PKKR 280
K P +T P +E TT+ + I K P AE P+A+ PK+
Sbjct: 837 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
Query: 281 GRKPGSVVAAAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV 337
G AA E K E +R+ ET K T+ET + K +
Sbjct: 897 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM-TKETATTTEKTTESKITA 955
Query: 338 STLGEKSGKGLKTC--KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 395
+T S T K K+ +PK +++ + E + + PK
Sbjct: 956 TTTQVTSTTTQDTTPFKITTLKTTTLAPKV-TTTKKTITTTEIMNKPEETAKPKDRATNS 1014
Query: 396 PPLPPPPPEP-ESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVAT 454
P P +P ++ + PTS +P + MPR ++ P++ T P +
Sbjct: 1015 KATTPKPQKPTKAPKKPTSTKKP----------KTMPRVRKPKTTPTPRKMTSTMPELNP 1064
Query: 455 AATAAE 460
+ AE
Sbjct: 1065 TSRIAE 1070
Score = 29.3 bits (64), Expect = 8.7
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 179 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQ-VKRVLE----------K 227
++ K PKKP S K P T +PK + T R +T + R+ E +
Sbjct: 1022 QKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 1081
Query: 228 SPGKLLVKMPFQTSPGGKAEG 248
+P LV++ ++ G AEG
Sbjct: 1082 TPNSKLVEVNPKSEDAGGAEG 1102
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 355 GRKSKESSPKGRSSSASSPPKKE----------HHHHHHHSESPKAPVPLLPPLPPPPPE 404
G+ ES K +SA +P + HHHHHHH P +P+ LLPP P P
Sbjct: 629 GKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGS 688
Query: 405 PESSEDPTSPPEP 417
P PP P
Sbjct: 689 ERHHPAPPPPPPP 701
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 355 GRKSKESSPKGRSSSASSPPKKE----------HHHHHHHSESPKAPVPLLPPLPPPPPE 404
G+ ES K +SA +P + HHHHHHH P +P+ LLPP P P
Sbjct: 629 GKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGS 688
Query: 405 PESSEDPTSPPEP 417
P PP P
Sbjct: 689 ERHHPAPPPPPPP 701
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 355 GRKSKESSPKGRSSSASSPPKKE----------HHHHHHHSESPKAPVPLLPPLPPPPPE 404
G+ ES K +SA +P + HHHHHHH P +P+ LLPP P P
Sbjct: 629 GKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGS 688
Query: 405 PESSEDPTSPPEP 417
P PP P
Sbjct: 689 ERHHPAPPPPPPP 701
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 52.0 bits (123), Expect = 1e-06
Identities = 73/324 (22%), Positives = 108/324 (33%), Gaps = 56/324 (17%)
Query: 177 PSRREQKPPKKPK--SPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLV 234
P +R PP+K + SP A R R RP T PK S Q KS
Sbjct: 374 PPKRTSSPPRKTRRLSPSA-SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSR----- 427
Query: 235 KMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKK------RGRKPGSVV 288
SPG T V K G +++ P P+K K G +
Sbjct: 428 ---VSVSPG----------RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474
Query: 289 AAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGL 348
AA + + +++ +++ S + + + ++ EV + +
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR-------RRHSPSR 527
Query: 349 KTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESS 408
SP ++ KE+SP+GR + SPP P P P P
Sbjct: 528 SASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS-----------------PSPAPPPRRR 570
Query: 409 EDPTSPPEPQDLSSSVCKEEKMPRGGS--LESDGCPKEPAKTQPAVATAATAAEKYKHRG 466
PT PP + S + PR S ++ P P K + A + K +
Sbjct: 571 RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA---SPPPPPKRRASP 627
Query: 467 EGERKDIVSSSMPRPNREEPVDSR 490
K VS S P R PV R
Sbjct: 628 SPPPKRRVSHSPPPKQRSSPVTKR 651
Score = 43.1 bits (100), Expect = 6e-04
Identities = 52/213 (24%), Positives = 82/213 (38%), Gaps = 32/213 (15%)
Query: 288 VAAAAAEAKKKAVKESSIRSVQETVLPIKKR-KTRETVSIEVKEVVKPLLVSTLGEKSGK 346
+ +A E KK+ +K+ I QE + +KK+ + ++ E KE S +
Sbjct: 119 IPSAFLELKKEEIKQRQIE--QEKLASMKKQDEDKDKRDKEEKE------------SSRE 164
Query: 347 GLKTCKSPGR-KSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEP 405
+ +SP R KS+ SP+ RSS K+ H H ++P P P P
Sbjct: 165 KRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
Query: 406 ESSEDPTSPPEPQDLSSS----VCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEK 461
E S P + S+S V K E +P PKEP+ + + +
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPE---------PKEPSPEKNSKKEKEKEKTR 275
Query: 462 YKHRGEGERKDIVSSSMP---RPNREEPVDSRT 491
+ R + + S P RP R SR+
Sbjct: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS 308
Score = 41.6 bits (96), Expect = 0.002
Identities = 67/297 (22%), Positives = 96/297 (32%), Gaps = 26/297 (8%)
Query: 174 RGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTR---------PKAATSEGVQVKRV 224
R SPSR P+K + +P GR R P T R P+ + +R
Sbjct: 522 RHSPSRSASPSPRKRQKETSP-RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR 580
Query: 225 LEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKR---- 280
P + P + SP + + + P KR+A P PK+R
Sbjct: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP--PKRRVSHS 638
Query: 281 ---GRKPGSVVAAAAAEAKKKAVKESS-IRSVQETVLPIKKRKTRETVSIEVKEVVKPLL 336
++ V + K K SS RS +E P ++ + +
Sbjct: 639 PPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP 698
Query: 337 VSTLGEKSGKGLKTCKSPG-----RKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKA- 390
G S + SP R S+ PK +AS P+ S S
Sbjct: 699 PVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE 758
Query: 391 PVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAK 447
P PP PP P + +S SP P + S PR E G K+ K
Sbjct: 759 PAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKK 815
Score = 39.3 bits (90), Expect = 0.008
Identities = 102/467 (21%), Positives = 155/467 (33%), Gaps = 61/467 (13%)
Query: 57 PVQPSAHHSAEPAEAGKAETSEGSGSAPAVP--------------EASASPKQRRSIIRD 102
PV+ SA + + + +S S S P P SASP +RR R
Sbjct: 344 PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH--RP 401
Query: 103 RGPMYDDPTL-----PEGWTRKLKQRKS---GRSAGKYDVYLINPQGKAFRSKVELIAYF 154
P P P+ R K R S GR++GK + +G R
Sbjct: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH----KGTEKRESPSPAPKP 457
Query: 155 EKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAA 214
KV + S D + S +R Q + +S G+ S RPK +
Sbjct: 458 RKV-ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS------SSSEDERPKRS 510
Query: 215 TSEGVQVKRVLEKSPGKLLVKMPF----QTSPGGKAEGGGATTSTQVMVIKRPGRKRKAE 270
+ +V R SP + P +TSP G+ + T+ P +
Sbjct: 511 HVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRR 570
Query: 271 ADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSV---QETVLPIKKRKTRETVSIE 327
P P++R P + + ++ S + T P K R + S
Sbjct: 571 RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP 630
Query: 328 VKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSES 387
K V S ++ + +SP SK KG S S S+ + + HS S
Sbjct: 631 PKRRVSH---SPPPKQRSSPVTKRRSPSLSSKHR--KGSSPSRSTREARSPQPNKRHSPS 685
Query: 388 PKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAK 447
P+ P PPP SS SP Q S S ++ R EP K
Sbjct: 686 PRPRAPQTSSSPPPVRRGASS----SPQRRQSPSPSTRPIRRVSR---------TPEPKK 732
Query: 448 TQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVT 494
+ A + + + + ++ P P PV S++P T
Sbjct: 733 IKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP-PAPPSPVQSQSPST 778
Score = 38.9 bits (89), Expect = 0.011
Identities = 97/465 (20%), Positives = 167/465 (35%), Gaps = 110/465 (23%)
Query: 25 SEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAP 84
S +++ G+ P F ++KK++ ++++ + E + + + K E S+
Sbjct: 111 SAQENIAGI---PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKE----SSR 163
Query: 85 AVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAF 144
E S SP++R+S R P + P RK +S R K P+ K
Sbjct: 164 EKRERSRSPRRRKS----RSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKK-- 217
Query: 145 RSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPK 204
EL KV + S+ + T T S + KP P+ PK P + + K
Sbjct: 218 EKTPELPEPSVKVKEPSVQ----EATST---SDILKVPKPEPIPE-PKEPSPEKNSKKEK 269
Query: 205 GSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPG 264
TRP++ R KS + + P T P + + S + +RP
Sbjct: 270 EKEKTRPRS---------RSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPR----RRPS 316
Query: 265 RKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETV 324
+R+ P R R P + + ++ P+++R+ R +
Sbjct: 317 PRRR--------PSPRRRTPPRRMPPPPRHRRSRS--------------PVRRRR-RSSA 353
Query: 325 SIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHH 384
S+ S K K K SP RK++ SP ++SPP++ H
Sbjct: 354 SLSGSSSSSSSSRSRSPPK--KPPKRTSSPPRKTRRLSP------SASPPRRRHRPS--- 402
Query: 385 SESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKE 444
PP PPP S P PQ + +
Sbjct: 403 -----------PPATPPPKTRHS-------PTPQQSNRT--------------------- 423
Query: 445 PAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 489
K++ +V+ T+ + KH+G +R+ S P+P + E +S
Sbjct: 424 -RKSRVSVSPGRTSGKVTKHKGTEKRES--PSPAPKPRKVELSES 465
Score = 37.7 bits (86), Expect = 0.024
Identities = 66/297 (22%), Positives = 106/297 (35%), Gaps = 49/297 (16%)
Query: 174 RGSPSRREQKPP-KKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKL 232
R SPS R PP ++ SP P R P PK S KR + SP
Sbjct: 588 RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP-----PKRRASPSPPPKRRVSHSPPPK 642
Query: 233 LVKMPF--QTSPGGKAE---GGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSV 287
P + SP ++ G + ST+ +P ++ P+A P+ P
Sbjct: 643 QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA-PQTSSSPPPVR 701
Query: 288 VAAAAAEAKKKAVKESS--IRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 345
A+++ ++++ S+ IR V T P K +K V+ V VS E +
Sbjct: 702 RGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAA 761
Query: 346 KGLKTCKSPGRKSKESS--------PKGRSSSAS-SPPK--------------------- 375
K SP + S+ K +S + S SPP+
Sbjct: 762 KKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKK 821
Query: 376 -KEHHHHHHHSE----SPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKE 427
K+H H H + + A + P + E+P + PEP+ + S ++
Sbjct: 822 DKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAED 878
Score = 37.7 bits (86), Expect = 0.024
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Query: 24 KSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKH---EPVQPSAHHSAEPAEAGKAETSEGS 80
++ DQ+ G K K K KK KKDKK +K KH + V +A + PA A T+
Sbjct: 800 RNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQ 859
Query: 81 GSAPAVPE 88
A PE
Sbjct: 860 EEPVAAPE 867
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 50.8 bits (120), Expect = 3e-06
Identities = 98/488 (20%), Positives = 164/488 (33%), Gaps = 78/488 (15%)
Query: 38 LKFKKVKKDKKEEKEGKHEPVQP-----SAHHSAEPAEAGKAETSEGSG----SAPAVPE 88
LK K+ +K+K +E K ++ S + E + GKA+ ++ S S+ E
Sbjct: 123 LKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKE 182
Query: 89 ASASPKQRRSIIRDRGPMYDDPTLPEG-----------------WTRKLKQRKSGRSAGK 131
+ ++ +S +DR + P+ W+ KQ S A
Sbjct: 183 KTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASY 242
Query: 132 YDVYLINPQGKAFRSKVELIAYFEKVGDTSL---------DPNDFDFTVTGRGSPSRREQ 182
Y ++P S + +Y + G TS +P+ + + SRR++
Sbjct: 243 GQDYDLSPSRSHTSSNYD--SYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 183 KPP----KKPKSPKAPGTGRGR-----GRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLL 233
++ S + G+ GR GR + S K + S R KS +
Sbjct: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP 360
Query: 234 VKMPFQTSPGGKAEGGGATTSTQVMVIKRP---------GRKRKAEADPQAIPKKRGRKP 284
+S K + + + ++ P RK+K A A K G++
Sbjct: 361 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES 420
Query: 285 -GSVVAAAAAEAKKKAVKESSIRS------------------VQETVLPIKKRKTRETVS 325
GS V E K+S + S V T L + + + +T
Sbjct: 421 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
Query: 326 IEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKG-RSSSASSPPKKEHHHHHHH 384
+++ E + LV L +G + K K + +PK +S +PP
Sbjct: 481 VKLDENSEKHLVKDL---KAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPP 537
Query: 385 SESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKE 444
P P PPLPP PP P + P PP S +
Sbjct: 538 PLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSS 597
Query: 445 PAKTQPAV 452
A +QP V
Sbjct: 598 QANSQPPV 605
Score = 32.0 bits (71), Expect = 1.3
Identities = 31/132 (23%), Positives = 53/132 (40%), Gaps = 19/132 (14%)
Query: 295 AKKKAVKESSIRSVQETVLPIKKRKTRETVSI--EVKEVVKPLLVSTLGEKSGKGLKTCK 352
A ++++KE+ V +LP ++ T E S +++ ++ LL + + G
Sbjct: 1174 APEESLKEAPSAPV---ILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAG---SL 1227
Query: 353 SPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPT 412
K S P+G + + P E P PP PPPPP P +
Sbjct: 1228 EENNSDKNSGPQGPRRTPTMP-----------QEEAAEKRPPEPPGPPPPPPPPPLVEGD 1276
Query: 413 SPPEPQDLSSSV 424
PQ+L+ +V
Sbjct: 1277 LSSAPQELNPAV 1288
Score = 30.0 bits (66), Expect = 5.1
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query: 362 SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLS 421
SPK + S P KKE H LL LP PP P P PEP+ ++
Sbjct: 644 SPK--ETLPSKPVKKEKEQRTRH---------LLTDLPLPPELPGGDLSPPDSPEPKAIT 692
Query: 422 SSVCKEEKMPR 432
+K P+
Sbjct: 693 PPQQPYKKRPK 703
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 50.8 bits (120), Expect = 3e-06
Identities = 98/488 (20%), Positives = 164/488 (33%), Gaps = 78/488 (15%)
Query: 38 LKFKKVKKDKKEEKEGKHEPVQP-----SAHHSAEPAEAGKAETSEGSG----SAPAVPE 88
LK K+ +K+K +E K ++ S + E + GKA+ ++ S S+ E
Sbjct: 123 LKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKE 182
Query: 89 ASASPKQRRSIIRDRGPMYDDPTLPEG-----------------WTRKLKQRKSGRSAGK 131
+ ++ +S +DR + P+ W+ KQ S A
Sbjct: 183 KTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASY 242
Query: 132 YDVYLINPQGKAFRSKVELIAYFEKVGDTSL---------DPNDFDFTVTGRGSPSRREQ 182
Y ++P S + +Y + G TS +P+ + + SRR++
Sbjct: 243 GQDYDLSPSRSHTSSNYD--SYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 183 KPP----KKPKSPKAPGTGRGR-----GRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLL 233
++ S + G+ GR GR + S K + S R KS +
Sbjct: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP 360
Query: 234 VKMPFQTSPGGKAEGGGATTSTQVMVIKRP---------GRKRKAEADPQAIPKKRGRKP 284
+S K + + + ++ P RK+K A A K G++
Sbjct: 361 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES 420
Query: 285 -GSVVAAAAAEAKKKAVKESSIRS------------------VQETVLPIKKRKTRETVS 325
GS V E K+S + S V T L + + + +T
Sbjct: 421 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
Query: 326 IEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKG-RSSSASSPPKKEHHHHHHH 384
+++ E + LV L +G + K K + +PK +S +PP
Sbjct: 481 VKLDENSEKHLVKDL---KAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPP 537
Query: 385 SESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKE 444
P P PPLPP PP P + P PP S +
Sbjct: 538 PLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSS 597
Query: 445 PAKTQPAV 452
A +QP V
Sbjct: 598 QANSQPPV 605
Score = 33.9 bits (76), Expect = 0.35
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 10/132 (7%)
Query: 295 AKKKAVKESSIRSVQETVLPIKKRKTRETVSI--EVKEVVKPLLVSTLGEKSGKGLKTCK 352
A ++++KE+ V +LP ++ T E S +++ ++ LL + + G
Sbjct: 1174 APEESLKEAPSAPV---ILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAG---SL 1227
Query: 353 SPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPT 412
K S P+G + + P ++ H K P P PPPPP P D +
Sbjct: 1228 EENNSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGDLS 1287
Query: 413 SPPEPQDLSSSV 424
S PQ+L+ +V
Sbjct: 1288 S--APQELNPAV 1297
Score = 30.0 bits (66), Expect = 5.1
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query: 362 SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLS 421
SPK + S P KKE H LL LP PP P P PEP+ ++
Sbjct: 644 SPK--ETLPSKPVKKEKEQRTRH---------LLTDLPLPPELPGGDLSPPDSPEPKAIT 692
Query: 422 SSVCKEEKMPR 432
+K P+
Sbjct: 693 PPQQPYKKRPK 703
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 50.8 bits (120), Expect = 3e-06
Identities = 104/478 (21%), Positives = 167/478 (34%), Gaps = 89/478 (18%)
Query: 2 AAAAAAAPSGGGGGGEEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKH------ 55
+AA AA +GG GG + +G + +P + ++ + +E+ +H
Sbjct: 163 SAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQ 222
Query: 56 ----EPVQPSAHHS---AEPAEAGKAETSEGSG----SAPAVPEASASPKQR-------- 96
E + + HS E AE K+ +S SG SA A +S+S K R
Sbjct: 223 RGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSR 282
Query: 97 -------RSIIRDRGPMY-DDPTLPEGWTRK---------------------LKQRKSGR 127
S ++ Y +D T P+ + R+ L+ RKS
Sbjct: 283 TKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPS 342
Query: 128 SAG----KYDVYL---INPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRR 180
AG Y L +P + + +E+ GD S P S
Sbjct: 343 PAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPY------------SSS 390
Query: 181 EQKPPKKPKSPKAPGTGRGRGR-PKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQ 239
+ + P SP +G+ R R P S +R ++ R SP L +K
Sbjct: 391 SWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLA 450
Query: 240 TSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKP--GSVVAAAAAEAKK 297
+ A + K + AEA +A P G+ +A+A ++
Sbjct: 451 AELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTETSASA-SQT 509
Query: 298 KAVKESSIRSVQETVLP-----IKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCK 352
VK+ ++ P +K K + ++V +V L+V +K+ K K
Sbjct: 510 NHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAVIVGKESK 569
Query: 353 SPGRKSKESSPKGRSSSAS-SPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSE 409
S K + S K ++ + S KE H LPPLP PP PE E
Sbjct: 570 SAATKEESVSLKEKTKPLTPSIGAKEKEQH------VALVTSTLPPLPLPPMLPEDKE 621
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 50.8 bits (120), Expect = 3e-06
Identities = 104/478 (21%), Positives = 167/478 (34%), Gaps = 89/478 (18%)
Query: 2 AAAAAAAPSGGGGGGEEERLEEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKH------ 55
+AA AA +GG GG + +G + +P + ++ + +E+ +H
Sbjct: 163 SAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQ 222
Query: 56 ----EPVQPSAHHS---AEPAEAGKAETSEGSG----SAPAVPEASASPKQR-------- 96
E + + HS E AE K+ +S SG SA A +S+S K R
Sbjct: 223 RGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSR 282
Query: 97 -------RSIIRDRGPMY-DDPTLPEGWTRK---------------------LKQRKSGR 127
S ++ Y +D T P+ + R+ L+ RKS
Sbjct: 283 TKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPS 342
Query: 128 SAG----KYDVYL---INPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRR 180
AG Y L +P + + +E+ GD S P S
Sbjct: 343 PAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPY------------SSS 390
Query: 181 EQKPPKKPKSPKAPGTGRGRGR-PKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQ 239
+ + P SP +G+ R R P S +R ++ R SP L +K
Sbjct: 391 SWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLA 450
Query: 240 TSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKP--GSVVAAAAAEAKK 297
+ A + K + AEA +A P G+ +A+A ++
Sbjct: 451 AELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTETSASA-SQT 509
Query: 298 KAVKESSIRSVQETVLP-----IKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCK 352
VK+ ++ P +K K + ++V +V L+V +K+ K K
Sbjct: 510 NHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAVIVGKESK 569
Query: 353 SPGRKSKESSPKGRSSSAS-SPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSE 409
S K + S K ++ + S KE H LPPLP PP PE E
Sbjct: 570 SAATKEESVSLKEKTKPLTPSIGAKEKEQH------VALVTSTLPPLPLPPMLPEDKE 621
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.125 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,519,331
Number of Sequences: 37866
Number of extensions: 1655907
Number of successful extensions: 26120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 610
Number of HSP's successfully gapped in prelim test: 1162
Number of HSP's that attempted gapping in prelim test: 13482
Number of HSP's gapped (non-prelim): 8412
length of query: 498
length of database: 18,247,518
effective HSP length: 106
effective length of query: 392
effective length of database: 14,233,722
effective search space: 5579619024
effective search space used: 5579619024
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.