Guide to the Human Genome
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Name: MBD3 Sequence: fasta or formatted (291aa) NCBI GI: 4505119
Description:

methyl-CpG binding domain protein 3

Referenced in:

DNA Methylation
Histones, Related Proteins, and Modifying Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.2         21           2
 C cysteine            1.4          4           1
 D aspartate           7.2         21           3
 E glutamate          10.3         30           7
 F phenylalanine       2.7          8           1
 G glycine             5.5         16           2
 H histidine           1.7          5           1
 I isoleucine          2.1          6           1
 K lysine              7.9         23           2
 L leucine             8.9         26           2
 M methionine          3.8         11           1
 N asparagine          2.7          8           1
 P proline             6.9         20           1
 Q glutamine           5.2         15           2
 R arginine            6.2         18           2
 S serine              6.5         19           2
 T threonine           5.2         15           2
 V valine              5.8         17           1
 W tryptophan          1.4          4           1
 Y tyrosine            1.4          4           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   methyl-CpG binding domain protein 3 
MBD2                  0.662   methyl-CpG binding domain protein 2 isoform 1 
MBD3L1                0.218   methyl-CpG binding domain protein 3-like 
MBD2                  0.189   methyl-CpG binding domain protein 2 testis-specific i...
LOC100134199          0.101   PREDICTED: similar to methyl-CpG binding domain pro...
MBD3L2                0.097   methyl-CpG binding domain protein 3-like 2 
MBD3L5                0.097   hypothetical protein LOC284428 
MBD3L3                0.096   PREDICTED: methyl-CpG-binding domain protein 3-like ...
LOC729458             0.096   PREDICTED: similar to methyl-CpG binding domain pro...
MBD3L4                0.096   PREDICTED: methyl-CpG-binding domain protein 3-like ...
MBD1                  0.087   methyl-CpG binding domain protein 1 isoform 2 
MBD1                  0.087   methyl-CpG binding domain protein 1 isoform 4 
MBD1                  0.087   methyl-CpG binding domain protein 1 isoform PCM1 [Ho...
MBD1                  0.087   methyl-CpG binding domain protein 1 isoform 1 
MBD1                  0.087   methyl-CpG binding domain protein 1 isoform 3 [Homo...
MECP2                 0.053   methyl CpG binding protein 2 isoform 2 
MECP2                 0.053   methyl CpG binding protein 2 isoform 1 
MBD4                  0.044   methyl-CpG binding domain protein 4 
RANGAP1               0.027   Ran GTPase activating protein 1 
BAZ2B                 0.027   bromodomain adjacent to zinc finger domain, 2B [Homo...
WDR52                 0.025   WD repeat domain 52 
G3BP2                 0.025   Ras-GTPase activating protein SH3 domain-binding pro...
G3BP2                 0.025   Ras-GTPase activating protein SH3 domain-binding pro...
G3BP2                 0.025   Ras-GTPase activating protein SH3 domain-binding pro...
RGAG4                 0.025   retrotransposon gag domain containing 4 
MYT1                  0.023   myelin transcription factor 1 
HMGB1L1               0.023   high-mobility group box 1-like 1 
MIER1                 0.023   mesoderm induction early response 1 isoform g [Homo...
MIER1                 0.023   mesoderm induction early response 1 isoform h [Homo...
MIER1                 0.023   mesoderm induction early response 1 isoform a [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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