Guide to the Human Genome
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Name: MBD1 Sequence: fasta or formatted (586aa) NCBI GI: 21464115
Description:

methyl-CpG binding domain protein 1 isoform 2

Referenced in:

DNA Methylation
Fibroblast Growth Factors

Other entries for this name:
alt prot [549aa] methyl-CpG binding domain protein 1 isoform 3
alt prot [605aa] methyl-CpG binding domain protein 1 isoform 1
alt prot [556aa] methyl-CpG binding domain protein 1 isoform PCM1
alt prot [503aa] methyl-CpG binding domain protein 1 isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.7         45           2
 C cysteine            6.7         39           2
 D aspartate           4.9         29           2
 E glutamate           5.6         33           3
 F phenylalanine       2.6         15           1
 G glycine             8.5         50           3
 H histidine           1.5          9           2
 I isoleucine          1.4          8           1
 K lysine              6.0         35           2
 L leucine             6.1         36           2
 M methionine          1.2          7           2
 N asparagine          1.2          7           1
 P proline            10.4         61           5
 Q glutamine           5.1         30           1
 R arginine           10.9         64           3
 S serine              7.2         42           2
 T threonine           5.6         33           1
 V valine              4.4         26           1
 W tryptophan          1.9         11           1
 Y tyrosine            1.0          6           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   methyl-CpG binding domain protein 1 isoform 2 
MBD1                  0.857   methyl-CpG binding domain protein 1 isoform 1 
MBD1                  0.768   methyl-CpG binding domain protein 1 isoform 4 
MBD1                  0.751   methyl-CpG binding domain protein 1 isoform PCM1 [Ho...
MBD1                  0.750   methyl-CpG binding domain protein 1 isoform 3 [Homo...
MBD2                  0.049   methyl-CpG binding domain protein 2 testis-specific i...
MBD2                  0.049   methyl-CpG binding domain protein 2 isoform 1 
MLL                   0.047   myeloid/lymphoid or mixed-lineage leukemia protein [...
CXXC1                 0.041   CXXC finger 1 (PHD domain) isoform 1 
CXXC1                 0.041   CXXC finger 1 (PHD domain) isoform 2 
MBD3                  0.040   methyl-CpG binding domain protein 3 
MLL4                  0.036   myeloid/lymphoid or mixed-lineage leukemia 4 
DNMT1                 0.024   DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...
DNMT1                 0.024   DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...
KDM2B                 0.024   F-box and leucine-rich repeat protein 10 isoform a [...
KDM2B                 0.024   F-box and leucine-rich repeat protein 10 isoform b [...
FBXL19                0.024   F-box and leucine-rich repeat protein 19 
MECP2                 0.024   methyl CpG binding protein 2 isoform 2 
MECP2                 0.024   methyl CpG binding protein 2 isoform 1 
KDM2A                 0.021   F-box and leucine-rich repeat protein 11 
TET1                  0.014   CXXC finger 6 
SPRED3                0.013   sprouty-related, EVH1 domain containing 3 isoform a...
LOC100289743          0.012   PREDICTED: hypothetical protein XP_002348163 
RPH3A                 0.012   rabphilin 3A homolog isoform 1 
RPH3A                 0.012   rabphilin 3A homolog isoform 2 
DMRT2                 0.012   doublesex and mab-3 related transcription factor 2 ...
LOC100293922          0.012   PREDICTED: hypothetical protein 
LOC100291358          0.012   PREDICTED: hypothetical protein XP_002347390 
CXXC5                 0.012   CXXC finger 5 
MBD4                  0.011   methyl-CpG binding domain protein 4 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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