Guide to the Human Genome
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Name: MBD1 Sequence: fasta or formatted (605aa) NCBI GI: 21464117
Description:

methyl-CpG binding domain protein 1 isoform 1

Referenced in:

DNA Methylation
Fibroblast Growth Factors

Other entries for this name:
alt prot [549aa] methyl-CpG binding domain protein 1 isoform 3
alt prot [586aa] methyl-CpG binding domain protein 1 isoform 2
alt prot [556aa] methyl-CpG binding domain protein 1 isoform PCM1
alt prot [503aa] methyl-CpG binding domain protein 1 isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.6         52           2
 C cysteine            6.4         39           2
 D aspartate           5.3         32           2
 E glutamate           5.8         35           3
 F phenylalanine       2.6         16           1
 G glycine             8.1         49           3
 H histidine           1.3          8           2
 I isoleucine          1.5          9           1
 K lysine              6.8         41           2
 L leucine             6.8         41           2
 M methionine          0.8          5           1
 N asparagine          1.0          6           1
 P proline            10.6         64           5
 Q glutamine           5.5         33           1
 R arginine           10.2         62           3
 S serine              6.0         36           2
 T threonine           5.3         32           1
 V valine              4.8         29           2
 W tryptophan          1.3          8           1
 Y tyrosine            1.3          8           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   methyl-CpG binding domain protein 1 isoform 1 
MBD1                  0.896   methyl-CpG binding domain protein 1 isoform PCM1 [Ho...
MBD1                  0.868   methyl-CpG binding domain protein 1 isoform 3 [Homo...
MBD1                  0.823   methyl-CpG binding domain protein 1 isoform 2 
MBD1                  0.761   methyl-CpG binding domain protein 1 isoform 4 
MBD2                  0.048   methyl-CpG binding domain protein 2 testis-specific i...
MBD2                  0.048   methyl-CpG binding domain protein 2 isoform 1 
MLL                   0.044   myeloid/lymphoid or mixed-lineage leukemia protein [...
CXXC1                 0.043   CXXC finger 1 (PHD domain) isoform 1 
CXXC1                 0.043   CXXC finger 1 (PHD domain) isoform 2 
MBD3                  0.039   methyl-CpG binding domain protein 3 
MLL4                  0.033   myeloid/lymphoid or mixed-lineage leukemia 4 
DNMT1                 0.027   DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...
DNMT1                 0.027   DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...
KDM2B                 0.024   F-box and leucine-rich repeat protein 10 isoform a [...
KDM2B                 0.024   F-box and leucine-rich repeat protein 10 isoform b [...
MECP2                 0.023   methyl CpG binding protein 2 isoform 2 
MECP2                 0.023   methyl CpG binding protein 2 isoform 1 
FBXL19                0.021   F-box and leucine-rich repeat protein 19 
KDM2A                 0.021   F-box and leucine-rich repeat protein 11 
ESPN                  0.013   espin 
TET1                  0.013   CXXC finger 6 
SETD1B                0.013   SET domain containing 1B 
LOC100132891          0.012   PREDICTED: hypothetical protein 
LOC100132891          0.012   PREDICTED: hypothetical protein 
LOC100132891          0.012   PREDICTED: hypothetical protein 
CXXC5                 0.012   CXXC finger 5 
MBD4                  0.011   methyl-CpG binding domain protein 4 
PRR12                 0.011   proline rich 12 
EP400                 0.011   E1A binding protein p400 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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