Guide to the Human Genome
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Name: AFF1 Sequence: fasta or formatted (1210aa) NCBI GI: 5174573
Description:

myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2

Referenced in:

Additional Genes in Development
PHD Finger Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.7         81           3
 C cysteine            1.2         14           1
 D aspartate           4.7         57           2
 E glutamate           6.8         82           2
 F phenylalanine       1.9         23           2
 G glycine             4.2         51           1
 H histidine           3.0         36           2
 I isoleucine          2.3         28           1
 K lysine              9.3        112           3
 L leucine             6.4         78           2
 M methionine          1.7         20           1
 N asparagine          2.5         30           2
 P proline            11.2        136           4
 Q glutamine           5.8         70           2
 R arginine            4.7         57           2
 S serine             16.3        197           7
 T threonine           5.8         70           2
 V valine              4.0         48           3
 W tryptophan          0.3          4           1
 Y tyrosine            1.3         16           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   myeloid/lymphoid or mixed-lineage leukemia trithorax ... 
AFF4                  0.281   ALL1 fused gene from 5q31 
AFF3                  0.217   AF4/FMR2 family, member 3 isoform 2 
AFF3                  0.216   AF4/FMR2 family, member 3 isoform 1 
AFF2                  0.128   fragile X mental retardation 2 
NEFH                  0.033   neurofilament, heavy polypeptide 200kDa 
NOLC1                 0.031   nucleolar and coiled-body phosphoprotein 1 
SRRM1                 0.030   serine/arginine repetitive matrix 1 
PCLO                  0.029   piccolo isoform 2 
PCLO                  0.029   piccolo isoform 1 
PRG4                  0.028   proteoglycan 4 isoform D 
PRG4                  0.028   proteoglycan 4 isoform C 
SRRM2                 0.027   splicing coactivator subunit SRm300 
PRG4                  0.027   proteoglycan 4 isoform B 
PRG4                  0.027   proteoglycan 4 isoform A 
DSPP                  0.023   dentin sialophosphoprotein preproprotein 
SCAF1                 0.022   SR-related CTD-associated factor 1 
RERE                  0.022   atrophin-1 like protein isoform b 
RERE                  0.022   atrophin-1 like protein isoform a 
RERE                  0.022   atrophin-1 like protein isoform a 
LOC100294236          0.021   PREDICTED: similar to diffuse panbronchiolitis crit...
LOC100170229          0.021   hypothetical protein LOC100170229 
MAPT                  0.021   microtubule-associated protein tau isoform 1 
TNRC18                0.021   trinucleotide repeat containing 18 
C2orf55               0.021   hypothetical protein LOC343990 
MAST4                 0.020   microtubule associated serine/threonine kinase fami...
MAPT                  0.020   microtubule-associated protein tau isoform 6 
KIAA1522              0.020   hypothetical protein LOC57648 
ATN1                  0.020   atrophin-1 
ATN1                  0.020   atrophin-1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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