Guide to the Human Genome
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Name: MBD2 Sequence: fasta or formatted (411aa) NCBI GI: 4505117
Description:

methyl-CpG binding domain protein 2 isoform 1

Referenced in:

DNA Methylation
DNases, Recombination, and DNA Repair
Histones, Related Proteins, and Modifying Enzymes
Small RNAs in RNA Processing
Testes and Sperm

Other entries for this name:
alt prot [302aa] methyl-CpG binding domain protein 2 testis-specific isoform
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         30           2
 C cysteine            1.5          6           2
 D aspartate           4.4         18           1
 E glutamate           6.1         25           2
 F phenylalanine       1.9          8           1
 G glycine            16.8         69           4
 H histidine           0.7          3           1
 I isoleucine          2.7         11           2
 K lysine              6.6         27           2
 L leucine             6.1         25           2
 M methionine          2.2          9           2
 N asparagine          2.9         12           1
 P proline             7.5         31           2
 Q glutamine           5.1         21           2
 R arginine            9.5         39           2
 S serine              8.5         35           2
 T threonine           3.9         16           2
 V valine              4.6         19           1
 W tryptophan          1.0          4           1
 Y tyrosine            0.7          3           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   methyl-CpG binding domain protein 2 isoform 1 
MBD2                  0.577   methyl-CpG binding domain protein 2 testis-specific i...
MBD3                  0.459   methyl-CpG binding domain protein 3 
MBD3L1                0.134   methyl-CpG binding domain protein 3-like 
MBD1                  0.075   methyl-CpG binding domain protein 1 isoform 2 
MBD1                  0.075   methyl-CpG binding domain protein 1 isoform 4 
MBD1                  0.075   methyl-CpG binding domain protein 1 isoform PCM1 [Ho...
MBD1                  0.075   methyl-CpG binding domain protein 1 isoform 1 
MBD1                  0.075   methyl-CpG binding domain protein 1 isoform 3 [Homo...
MBD3L3                0.066   PREDICTED: methyl-CpG-binding domain protein 3-like ...
LOC729458             0.066   PREDICTED: similar to methyl-CpG binding domain pro...
MBD3L2                0.066   methyl-CpG binding domain protein 3-like 2 
LOC100134199          0.066   PREDICTED: similar to methyl-CpG binding domain pro...
MBD3L4                0.066   PREDICTED: methyl-CpG-binding domain protein 3-like ...
MBD3L5                0.066   hypothetical protein LOC284428 
FAM98B                0.061   family with sequence similarity 98, member B isofor...
MECP2                 0.060   methyl CpG binding protein 2 isoform 2 
MECP2                 0.060   methyl CpG binding protein 2 isoform 1 
KRT9                  0.054   keratin 9 
KRT2                  0.052   keratin 2 
KRT10                 0.050   keratin 10 
LOR                   0.050   loricrin 
KRT1                  0.050   keratin 1 
IRS4                  0.050   insulin receptor substrate 4 
KRT3                  0.049   keratin 3 
FBL                   0.045   fibrillarin 
C1orf77               0.045   small protein rich in arginine and glycine 
TAF15                 0.041   TBP-associated factor 15 isoform 2 
TAF15                 0.041   TBP-associated factor 15 isoform 1 
PPP1R10               0.039   protein phosphatase 1, regulatory subunit 10 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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