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Search of human proteins with 110347457
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
(1541 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 3580 0.0
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 720 0.0
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 717 0.0
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 616 e-176
gi|148833508 notch1 preproprotein [Homo sapiens] 460 e-129
gi|134244285 Notch homolog 3 [Homo sapiens] 435 e-121
gi|24041035 notch 2 preproprotein [Homo sapiens] 398 e-110
gi|55770876 notch4 preproprotein [Homo sapiens] 386 e-107
gi|56237021 fibrillin 3 precursor [Homo sapiens] 338 2e-92
gi|66346695 fibrillin 2 precursor [Homo sapiens] 304 4e-82
gi|24430141 fibrillin 1 precursor [Homo sapiens] 295 3e-79
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 285 3e-76
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 281 4e-75
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 281 4e-75
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 264 4e-70
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 264 4e-70
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 249 1e-65
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 249 1e-65
gi|10190748 CEGP1 protein [Homo sapiens] 249 1e-65
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 248 2e-65
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 247 7e-65
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 244 6e-64
gi|110347437 latent transforming growth factor beta binding prot... 233 1e-60
gi|110347412 latent transforming growth factor beta binding prot... 233 1e-60
gi|110347431 latent transforming growth factor beta binding prot... 233 1e-60
gi|122937283 6720455I24Rik homolog [Homo sapiens] 232 2e-60
gi|194328809 latent transforming growth factor beta binding prot... 226 1e-58
gi|21264602 laminin alpha 5 [Homo sapiens] 223 1e-57
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 221 6e-57
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 215 2e-55
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 3580 bits (9284), Expect = 0.0
Identities = 1541/1541 (100%), Positives = 1541/1541 (100%)
Query: 1 MSFLEEARAAGRAVVLALVLLLLPAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQ 60
MSFLEEARAAGRAVVLALVLLLLPAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQ
Sbjct: 1 MSFLEEARAAGRAVVLALVLLLLPAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQ 60
Query: 61 PCVQALSHTVPVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDE 120
PCVQALSHTVPVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDE
Sbjct: 61 PCVQALSHTVPVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDE 120
Query: 121 EGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTP 180
EGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTP
Sbjct: 121 EGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTP 180
Query: 181 GSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGR 240
GSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGR
Sbjct: 181 GSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGR 240
Query: 241 HCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC 300
HCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC
Sbjct: 241 HCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC 300
Query: 301 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 360
LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG
Sbjct: 301 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 360
Query: 361 YELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSR 420
YELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSR
Sbjct: 361 YELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSR 420
Query: 421 GGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDE 480
GGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDE
Sbjct: 421 GGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDE 480
Query: 481 LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGC 540
LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGC
Sbjct: 481 LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGC 540
Query: 541 DCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPK 600
DCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPK
Sbjct: 541 DCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPK 600
Query: 601 GYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH 660
GYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH
Sbjct: 601 GYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH 660
Query: 661 TQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPA 720
TQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPA
Sbjct: 661 TQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPA 720
Query: 721 GFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGL 780
GFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGL
Sbjct: 721 GFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGL 780
Query: 781 GCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP 840
GCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP
Sbjct: 781 GCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP 840
Query: 841 ATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRC 900
ATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRC
Sbjct: 841 ATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRC 900
Query: 901 EQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC 960
EQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC
Sbjct: 901 EQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC 960
Query: 961 NCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHC 1020
NCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHC
Sbjct: 961 NCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHC 1020
Query: 1021 APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRD 1080
APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRD
Sbjct: 1021 APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRD 1080
Query: 1081 VRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAAC 1140
VRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAAC
Sbjct: 1081 VRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAAC 1140
Query: 1141 HHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGP 1200
HHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGP
Sbjct: 1141 HHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGP 1200
Query: 1201 SCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTH 1260
SCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTH
Sbjct: 1201 SCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTH 1260
Query: 1261 VCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSC 1320
VCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSC
Sbjct: 1261 VCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSC 1320
Query: 1321 SCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPP 1380
SCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPP
Sbjct: 1321 SCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPP 1380
Query: 1381 GFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGA 1440
GFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGA
Sbjct: 1381 GFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGA 1440
Query: 1441 PCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMG 1500
PCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMG
Sbjct: 1441 PCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMG 1500
Query: 1501 PTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH 1541
PTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
Sbjct: 1501 PTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH 1541
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 720 bits (1858), Expect = 0.0
Identities = 311/709 (43%), Positives = 372/709 (52%), Gaps = 8/709 (1%)
Query: 758 CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVC 817
C C PG G DC + C WG C C CQ+ A C+P TGAC+C GF G RC+++C
Sbjct: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQ-CQNGALCNPITGACVCAAGFRGWRCEELC 176
Query: 818 PAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSA 877
G +G CQ C C + C P G C CAPG+TG C+ C G G C C C
Sbjct: 177 APGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQN 236
Query: 878 GHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG 937
G G+C I+G C C G+ G C Q CP G FG C Q C C HG CDHV+G C C AG
Sbjct: 237 G-GTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAG 295
Query: 938 WRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAET-CPAHTYG 996
+ G C+ CP G FG C C+C G C G+C C G +GPRC E CP +G
Sbjct: 296 YMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHG 355
Query: 997 HNCSQACACF--NGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC 1054
C+ C C N SC PV G C C PGW G C ++CP G YGD C+ C CQNG C
Sbjct: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADC 415
Query: 1055 DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDK 1114
++G C C G+ G C C C C NGG C P G C C GW G
Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLD 475
Query: 1115 CQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQM 1174
C PC G +G C + C+C GAAC + G+C C PG+ G CE CP G+FG +C++
Sbjct: 476 CTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEH 535
Query: 1175 CQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGAC 1234
C C + C P TG C C AG+ G C CPPGR+GP C C C NGGSC G+C
Sbjct: 536 CDCSHAD-GCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC 594
Query: 1235 RCPTGFLGTDCNLTCPQGRFGPNCTHVCGC--GQGAACDPVTGTCLCPPGRAGVRCERGC 1292
C GF G C CP G +G C C C ++G C C PG +G C + C
Sbjct: 595 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVC 654
Query: 1293 PQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHN 1352
FG C CSC N G C +GSC C GW G+ C ACPPG +G AC CSCHN
Sbjct: 655 AGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHN 714
Query: 1353 NSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGF 1412
++C G C C PG+ G C CP F G C +C CQ+GA CD ISG+C C GF
Sbjct: 715 GASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGF 774
Query: 1413 HGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCN 1461
G CE+ C PG+FG GC Q C+C + CD VTG C C PG G C+
Sbjct: 775 TGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCD 823
Score = 718 bits (1853), Expect = 0.0
Identities = 322/758 (42%), Positives = 398/758 (52%), Gaps = 32/758 (4%)
Query: 628 CDPGLY--GRFCHLTCPPWAFGPGCSEEC---QCVQPHTQSCDKRDGSCSCKAGFRGERC 682
C PG Y G FC P C+EEC +CV P T C C+ G+ G C
Sbjct: 88 CCPGYYESGDFCI---------PLCTEECVHGRCVSPDT---------CHCEPGWGGPDC 129
Query: 683 QAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSS 742
+ C+ ++GP C C C G C+ ++G C C AGF+G C + C GT G C
Sbjct: 130 SSGCDSDHWGPHCSNRCQCQNGALCNPITGACV--CAAGFRGWRCEELCAPGTHGKGCQL 187
Query: 743 SCSCG-GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA 801
C C GA C G+C C PG TG CE CP G G C+ CP CQ+ C TG
Sbjct: 188 PCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCP-CQNGGTCHHITGE 246
Query: 802 CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACD 861
C C PG+ G+ C CP G +G +C C C + G C TG C C G+ G CQ C
Sbjct: 247 CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECP 306
Query: 862 TGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQ-CPQGHFGPGCEQRCQCQ 920
G +G CS C+C G G C +G C CE GY GPRC+++ CP+G GPGC C C
Sbjct: 307 FGSFGFQCSQHCDCHNG-GQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCD 365
Query: 921 --HGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCP 978
+ +C V+GACTC GW G C +CP G++G C+ C C GA C ++ G C C
Sbjct: 366 ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCA 425
Query: 979 AGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLY 1038
G G CA +C A TYG NCS C+C NG +C PV G C C GW G C CP+G +
Sbjct: 426 PGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTW 485
Query: 1039 GDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCD 1098
G NC SC C NG C P+ G C+C GW G CE C C C + CD
Sbjct: 486 GLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCD 545
Query: 1099 PHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC 1158
P TG C C AGWTG +C S C G +G C+ CSC G +C G+C C PGF G C
Sbjct: 546 PVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 605
Query: 1159 EQACPPGSFGEDCAQMCQ-CPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQ 1217
++ CPPG +G CAQ C C + CH +G C C G+ G C Q C G +G C Q
Sbjct: 606 QRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ 665
Query: 1218 LCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTC 1277
LC C N G+C G+C+C G++G DC+ CP G +GP C H C C GA+C G C
Sbjct: 666 LCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGAC 725
Query: 1278 LCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPP 1337
C PG G+ C + CP FG C C C+NG C +G C+C G+TG+HCE C P
Sbjct: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAP 785
Query: 1338 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
G +G C C C NNSTC+ TGTC C PGF G C+
Sbjct: 786 GTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCD 823
Score = 717 bits (1850), Expect = 0.0
Identities = 322/751 (42%), Positives = 394/751 (52%), Gaps = 21/751 (2%)
Query: 681 RCQAECELGYFGPG--CWQACTCPVGVACDSVSGECGK----RCPAGFQGEDCGQECPVG 734
R +++C GY+ G C CT + V G C C G+ G DC C
Sbjct: 83 RRRSQCCPGYYESGDFCIPLCTE------ECVHGRCVSPDTCHCEPGWGGPDCSSGCDSD 136
Query: 735 TFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA 793
+G +CS+ C C GA C+ +TG C C G G CE C G G GCQ C C+H A
Sbjct: 137 HWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQ-CRHGA 195
Query: 794 RCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTG 853
CDP G CLC PG+ G C+++CP G +G C+ RC C N G CH TG C+C PGWTG
Sbjct: 196 SCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTG 255
Query: 854 FSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGC 913
C + C G +G +CS C C G G CD ++G C C AGY+G RC+++CP G FG C
Sbjct: 256 AVCAQPCPPGTFGQNCSQDCPCHHG-GQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQC 314
Query: 914 EQRCQCQHGAACDHVSGACTCPAGWRGTFC-EHACPAGFFGLDCRSACNCTAG--AACDA 970
Q C C +G C +GAC C G++G C E CP G G C C C A +C
Sbjct: 315 SQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHP 374
Query: 971 VNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCL 1030
V G+C C G G C E+CP YG C C C NGA C + G C CAPG+MG C
Sbjct: 375 VTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCA 434
Query: 1031 QACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGG 1090
+C AG YG NC C C NGGTC PV G C C EGW GL C C C S
Sbjct: 435 VSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCT 494
Query: 1091 CLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCP 1150
C NG C P G C C GW GD C+ PC G FG C++ C C C VTG C C
Sbjct: 495 CANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCL 554
Query: 1151 PGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGR 1210
G+TG C+ CPPG +G +C+ C C +C P G+C CA G+ GP CQ+ CPPG
Sbjct: 555 AGWTGIRCDSTCPPGRWGPNCSVSCSCENGG-SCSPEDGSCECAPGFRGPLCQRICPPGF 613
Query: 1211 YGPGCEQLCG-CLNGGS-CDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGA 1268
YG GC Q C C++ C +G C C GF G CN C G FG +C +C C
Sbjct: 614 YGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNG 673
Query: 1269 ACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTG 1328
C P+ G+C C PG G C + CP +G C H CSC NG C A +G+C C GWTG
Sbjct: 674 TCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTG 733
Query: 1329 RHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQ 1388
C CP +G C C C N ++C+ +G C C GF GQ CE C PG G GCQ
Sbjct: 734 LFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQ 793
Query: 1389 GLCWCQHGAPCDPISGRCLCPAGFHGHFCER 1419
LC C + + CD ++G C C GF G C++
Sbjct: 794 QLCECMNNSTCDHVTGTCYCSPGFKGIRCDQ 824
Score = 695 bits (1794), Expect = 0.0
Identities = 314/735 (42%), Positives = 387/735 (52%), Gaps = 12/735 (1%)
Query: 517 GHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC 576
G C C + G C+ D C C GW G C+ C D +G +CS C CQNG C
Sbjct: 96 GDFCIPLCTEECVHGRCV-SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALC 154
Query: 577 DSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRF 636
+ +TGAC C G G CE+ C G +GK C+ C C + C G CLC PG G +
Sbjct: 155 NPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVY 214
Query: 637 CHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCW 696
C CPP + G C C C T C G C+C G+ G C C G FG C
Sbjct: 215 CEELCPPGSHGAHCELRCPCQNGGT--CHHITGECACPPGWTGAVCAQPCPPGTFGQNCS 272
Query: 697 QACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVT 755
Q C C G CD V+G+C C AG+ G+ C +ECP G+FG CS C C G C T
Sbjct: 273 QDCPCHHGGQCDHVTGQC--HCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTT 330
Query: 756 GQCRCPPGRTGEDC-EADCPEGRWGLGCQEICPA-CQHAARCDPETGACLCLPGFVGSRC 813
G C C PG G C E CPEG G GC CP + C P TGAC C PG+ G C
Sbjct: 331 GACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC 390
Query: 814 QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC 873
+ CP G+YG CQ C+C N CH TG C+CAPG+ G C +C G +GP+CS C
Sbjct: 391 NESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSIC 450
Query: 874 NCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACT 933
+C+ G G+C + G C C+ G+ G C CP G +G C + C C +GAAC + G+C+
Sbjct: 451 SCNNG-GTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCS 509
Query: 934 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAH 993
C GW G CE CP G FGL+C C+C+ CD V G C C AG G RC TCP
Sbjct: 510 CTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPG 569
Query: 994 TYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSC-LC-QNG 1051
+G NCS +C+C NG SC P G C CAPG+ GP C + CP G YG C C LC +
Sbjct: 570 RWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSS 629
Query: 1052 GTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWT 1111
C +SG C C G++G C + C C C N G C P G C C GW
Sbjct: 630 RPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWI 689
Query: 1112 GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDC 1171
G C C G++G AC CSC GA+C GAC C PG+TG C Q CP FG+DC
Sbjct: 690 GKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDC 749
Query: 1172 AQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAAT 1231
++CQC +C +G C+C G+ G C+QRC PG +G GC+QLC C+N +CD T
Sbjct: 750 GRVCQCQ-NGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVT 808
Query: 1232 GACRCPTGFLGTDCN 1246
G C C GF G C+
Sbjct: 809 GTCYCSPGFKGIRCD 823
Score = 677 bits (1747), Expect = 0.0
Identities = 298/700 (42%), Positives = 361/700 (51%), Gaps = 14/700 (2%)
Query: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570
C D +G CS C C+NG C C C G+ G C E C P T GK C C C
Sbjct: 133 CDSDHWGPHCSNRCQ-CQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQC 191
Query: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDP 630
++G +CD G C C PG +G CE+ CP G +G HC +C C N G CH + G C C P
Sbjct: 192 RHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPP 251
Query: 631 GLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY 690
G G C CPP FG CS++C C H CD G C C AG+ G+RCQ EC G
Sbjct: 252 GWTGAVCAQPCPPGTFGQNCSQDCPC--HHGGQCDHVTGQCHCTAGYMGDRCQEECPFGS 309
Query: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQE-CPVGTFGVNCSSSCSCGG- 748
FG C Q C C G C +G C C G++G C + CP G G C+ C C
Sbjct: 310 FGFQCSQHCDCHNGGQCSPTTGAC--ECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDAD 367
Query: 749 --APCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLP 806
CH VTG C C PG +G C CP G +G GCQ C CQ+ A C TG C C P
Sbjct: 368 NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPC-TCQNGADCHSITGGCTCAP 426
Query: 807 GFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG 866
GF+G C C AG YGP+C + CSC N G C P G C+C GW G C C +G WG
Sbjct: 427 GFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG 486
Query: 867 PDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACD 926
+C+ C C+ G +C I G C C G++G CE CP G FG C + C C H CD
Sbjct: 487 LNCNESCTCANG-AACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCD 545
Query: 927 HVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC 986
V+G C C AGW G C+ CP G +G +C +C+C G +C +GSC C G RGP C
Sbjct: 546 PVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 605
Query: 987 AETCPAHTYGHNCSQAC--ACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRH 1044
CP YGH C+Q C + C + G C C PG+ G C Q C G +G +C
Sbjct: 606 QRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ 665
Query: 1045 SCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRC 1104
C C N GTC P+ G C C GW G C + C P C H+ C NG C G C
Sbjct: 666 LCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGAC 725
Query: 1105 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPP 1164
C GWTG C C +FG+ C + C C GA+C H++G C C GFTG CEQ C P
Sbjct: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAP 785
Query: 1165 GSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ 1204
G+FG C Q+C+C N C TGTC C+ G+ G C Q
Sbjct: 786 GTFGYGCQQLCECM-NNSTCDHVTGTCYCSPGFKGIRCDQ 824
Score = 669 bits (1727), Expect = 0.0
Identities = 299/756 (39%), Positives = 376/756 (49%), Gaps = 56/756 (7%)
Query: 812 RCQDVCPAGWY--GPSCQTRCS--CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP 867
R + C G+Y G C C+ C + P T C C PGW G C CD+ HWGP
Sbjct: 83 RRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDT--CHCEPGWGGPDCSSGCDSDHWGP 140
Query: 868 DCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDH 927
CS+ C C G C+ I+G C+C AG+ G RCE+ C G G GC+ CQC+HGA+CD
Sbjct: 141 HCSNRCQCQNG-ALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDP 199
Query: 928 VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA 987
+G C C G+ G +CE CP G G C C C G C + G C CP G G CA
Sbjct: 200 RAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCA 259
Query: 988 ETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL 1047
+ CP T+G NCSQ C C +G CD V GQCHC G+MG C + CP G +G C C
Sbjct: 260 QPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCD 319
Query: 1048 CQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRA-GCRHSGGCL--NGGLCDPHTGRC 1104
C NGG C P +G C C G+ G C++ P + GC C N C P TG C
Sbjct: 320 CHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGAC 379
Query: 1105 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPP 1164
C GW+G C C G++G+ C C+C GA CH +TG C C PGF G C +C
Sbjct: 380 TCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAA 439
Query: 1165 GSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNG 1224
G++G +C+ +C C C P G+C+C G+ G C CP G +G C + C C NG
Sbjct: 440 GTYGPNCSSICSC-NNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498
Query: 1225 GSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRA 1284
+C G+C C G+LG C L CP G FG NC+ C C CDPVTG C C G
Sbjct: 499 AACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWT 558
Query: 1285 GVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAAC 1344
G+RC+ CP R+G C +CSC NGG C +GSC C G+ G C+ CPPG YG C
Sbjct: 559 GIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGC 618
Query: 1345 ---------------HLE------------------------------CSCHNNSTCEPA 1359
H+ CSC NN TC P
Sbjct: 619 AQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPI 678
Query: 1360 TGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCER 1419
G+C+C PG+ G+ C CPPGF G C C C +GA C G C C G+ G FC +
Sbjct: 679 DGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQ 738
Query: 1420 GCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDC 1479
C FG+ C + C C GA CD ++G C C G +G C C G FG C C+C
Sbjct: 739 RCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCEC 798
Query: 1480 GGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENP 1515
+ CD V+G C+C G+ G C + + NP
Sbjct: 799 MNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNP 834
Score = 629 bits (1623), Expect = e-180
Identities = 308/792 (38%), Positives = 378/792 (47%), Gaps = 90/792 (11%)
Query: 335 CEANNGG--CSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGG 392
CE GG CS GC GP C+ + C CQ NP
Sbjct: 120 CEPGWGGPDCSSGCDSDHWGPHCS-----------------NRCQ----CQNGALCNPIT 158
Query: 393 YECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCS 452
C C AG+R G CE++ + GC+ C G+ C AG L C+
Sbjct: 159 GACVCAAGFR----GWRCEELCAPGTHGKGCQLPCQCRHGA-SCDPRAGECL------CA 207
Query: 453 PLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCL 512
P + V +EL C
Sbjct: 208 P------------------GYTGVYCEEL-----------------------------CP 220
Query: 513 DDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQN 572
S G C L C C+NGGTC C CP GWTG +C + CPP TFG+NCS C C +
Sbjct: 221 PGSHGAHCELRCP-CQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHH 279
Query: 573 GGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGL 632
GG CD VTG C C G G C++ CP G +G C + C+C N G+C GAC C+PG
Sbjct: 280 GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGY 339
Query: 633 YGRFCH-LTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYF 691
G C CP GPGC+ C C +T SC G+C+C+ G+ G C C +GY+
Sbjct: 340 KGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYY 399
Query: 692 GPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG-GAP 750
G GC CTC G C S++G C C GF GE C C GT+G NCSS CSC G
Sbjct: 400 GDGCQLPCTCQNGADCHSITGGC--TCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGT 457
Query: 751 CHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVG 810
C V G C C G G DC CP G WGL C E C C + A C P G+C C PG++G
Sbjct: 458 CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC-TCANGAACSPIDGSCSCTPGWLG 516
Query: 811 SRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCS 870
C+ CP G +G +C C C++ C P TGHC C GWTG C C G WGP+CS
Sbjct: 517 DTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCS 576
Query: 871 HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQ-CQHGAA-CDHV 928
C+C G GSC G C C G+ GP C++ CP G +G GC Q C C H + C H+
Sbjct: 577 VSCSCENG-GSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHI 635
Query: 929 SGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE 988
SG C C G+ G C C G+FG DC C+C C ++GSC C G G C++
Sbjct: 636 SGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ 695
Query: 989 TCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLC 1048
CP +G C AC+C NGASC G CHC PGW G C Q CPA +G +C C C
Sbjct: 696 ACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQC 755
Query: 1049 QNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPA 1108
QNG +CD +SG C C G+ G CE+ C P GC+ C+N CD TG C C
Sbjct: 756 QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSP 815
Query: 1109 GWTGDKCQSPCL 1120
G+ G +C L
Sbjct: 816 GFKGIRCDQAAL 827
Score = 373 bits (958), Expect = e-103
Identities = 269/878 (30%), Positives = 335/878 (38%), Gaps = 126/878 (14%)
Query: 38 LPLQPGMPHVCAEQELTLVGRRQPCVQALSHTVPVWKAGC----GWQAWCVGHERRTVYY 93
L L P P+VC+ E V ++ ++ C W C H R Y
Sbjct: 18 LALNPEDPNVCSHWESYAVTVQESYAHPFDQ---IYYTRCTDILNWFK-CTRH--RISYK 71
Query: 94 MGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGF 153
YR+ T R +CC G+ E G C HG RCV S CHC PG+
Sbjct: 72 TAYRRGLRTMYRRRSQCCPGYY----ESGDFCIPLCTEECVHG-RCV--SPDTCHCEPGW 124
Query: 154 QGPRCQ--YDVDECRTHNGG---CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL 208
GP C D D H CQ+ + P + C C GFR C + +
Sbjct: 125 GGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR----GWRCEELCAPGT 180
Query: 209 GNGGCQ-----HHCVQLTITRHRCQCRPGF---------QLQEDGRHCVRRSPCANRNGS 254
GCQ H C C PG+ G HC R PC N G+
Sbjct: 181 HGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQN-GGT 239
Query: 255 CMH---RCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH---GCLNTQGSFK 308
C H C G C G+ C C G QC H C T G
Sbjct: 240 CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHG-GQCDHVTGQCHCTAGYMG 298
Query: 309 CVCHAGYELGADGRQCYRIEMEIVNSCEANNGG-CSH-----GCSHTSAGPLC---TCPR 359
C G+ G QC + C+ +NGG CS C GP C CP
Sbjct: 299 DRCQEECPFGSFGFQCSQ-------HCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPE 351
Query: 360 GYELDTDQRTC-IDVDDCADSPCCQQVCTNNPG--GYEC--GCYAGYRLSADG----CGC 410
G C D D+ CT PG G+ C C GY DG C C
Sbjct: 352 GLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGY--YGDGCQLPCTC 409
Query: 411 EDVDECASSRGGCEHHCTNLAGSFQCSCEAG------YRLHEDRRG--CSPLEEPMVDLD 462
++ +C S GGC + SC AG + G CSP++ +
Sbjct: 410 QNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKE 469
Query: 463 GELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSL 522
G LP C ++G +C+
Sbjct: 470 GWQGLDCTLP--------------------------------------CPSGTWGLNCNE 491
Query: 523 TCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGA 582
+C C NG C C C GW G C CP TFG NCS C C + CD VTG
Sbjct: 492 SC-TCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGH 550
Query: 583 CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCP 642
C C G +G C+ CP G +G +C C+C N G C G+C C PG G C CP
Sbjct: 551 CCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICP 610
Query: 643 PWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCP 702
P +G GC++ C ++ C G C C GF G C C GYFG C Q C+C
Sbjct: 611 PGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCA 670
Query: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCP 761
C + G C +C G+ G+DC Q CP G +G C +CSC GA C G C C
Sbjct: 671 NNGTCSPIDGSC--QCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCT 728
Query: 762 PGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGW 821
PG TG C CP +G C +C CQ+ A CD +G C C GF G C+ C G
Sbjct: 729 PGWTGLFCTQRCPAAFFGKDCGRVC-QCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGT 787
Query: 822 YGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRA 859
+G CQ C C N+ C TG C C+PG+ G C +A
Sbjct: 788 FGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQA 825
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 717 bits (1851), Expect = 0.0
Identities = 316/758 (41%), Positives = 405/758 (53%), Gaps = 32/758 (4%)
Query: 628 CDPGLY--GRFCHLTCPPWAFGPGCSEEC---QCVQPHTQSCDKRDGSCSCKAGFRGERC 682
C PG Y G C P C+++C +C+ P+T C C+ G+ G C
Sbjct: 94 CCPGFYESGEMCV---------PHCADKCVHGRCIAPNT---------CQCEPGWGGTNC 135
Query: 683 QAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSS 742
+ C+ ++GP C C C G C+ ++G C C AGF+G C C GT+G +C
Sbjct: 136 SSACDGDHWGPHCTSRCQCKNGALCNPITGAC--HCAAGFRGWRCEDRCEQGTYGNDCHQ 193
Query: 743 SCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA 801
C C GA C VTG+CRCPPG TG CE CP G+ G C++ CP CQ+ C TG
Sbjct: 194 RCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCP-CQNGGVCHHVTGE 252
Query: 802 CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACD 861
C C G++G+ C CP G +G +C C C N G C ATG C C+PG+TG CQ C
Sbjct: 253 CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECP 312
Query: 862 TGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQ-CPQGHFGPGCEQRCQC- 919
G +G C+ C C G G C +SG CLCEAG+ G RCE + CP+G +G C++RC C
Sbjct: 313 VGTYGVLCAETCQCVNG-GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCH 371
Query: 920 -QHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCP 978
++ +C +SG C C GW G +C C GF+G C+ C+C GA CD+V G C C
Sbjct: 372 LENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCA 431
Query: 979 AGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLY 1038
G +G C+ CP TYG NCS C C N A C PV G C C GW G C CP+G +
Sbjct: 432 PGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTW 491
Query: 1039 GDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCD 1098
G C +C C NGG C+ + G C C GW G CE C C C + C
Sbjct: 492 GFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCH 551
Query: 1099 PHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC 1158
P TG C C GW+G C S C G +G C+ C C GA+C G C C PGF G+ C
Sbjct: 552 PTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTC 611
Query: 1159 EQACPPGSFGEDCAQMC-QCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQ 1217
++ C PG +G C+Q C QC + CH TG C C G+ G C + CP GR+G C
Sbjct: 612 QRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAG 671
Query: 1218 LCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTC 1277
+C C N G+C+ +C+C G++G+DC+ CP +GPNC H C C GA C G C
Sbjct: 672 ICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGEC 731
Query: 1278 LCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPP 1337
C PG G+ C + CP +G C C C+NG C +G C+C G+ GRHCE CP
Sbjct: 732 KCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPS 791
Query: 1338 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
G YG C C C NNSTC+ TGTC C PG+ G C+
Sbjct: 792 GTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
Score = 708 bits (1827), Expect = 0.0
Identities = 317/749 (42%), Positives = 402/749 (53%), Gaps = 17/749 (2%)
Query: 681 RCQAECELGYFGPGCWQACTCPVGVACDSVSGECGK----RCPAGFQGEDCGQECPVGTF 736
R +++C G++ G + C C V G C +C G+ G +C C +
Sbjct: 89 RRKSQCCPGFYESG--EMCVPHCADKC--VHGRCIAPNTCQCEPGWGGTNCSSACDGDHW 144
Query: 737 GVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARC 795
G +C+S C C GA C+ +TG C C G G CE C +G +G C + C CQ+ A C
Sbjct: 145 GPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQ-CQNGATC 203
Query: 796 DPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFS 855
D TG C C PG+ G+ C+D+CP G +GP C+ RC C N G CH TG CSC GW G
Sbjct: 204 DHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTV 263
Query: 856 CQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQ 915
C + C G +G +CS C C G G+CDA +G C C GY G RC+ +CP G +G C +
Sbjct: 264 CGQPCPEGRFGKNCSQECQCHNG-GTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAE 322
Query: 916 RCQCQHGAACDHVSGACTCPAGWRGTFCE-HACPAGFFGLDCRSACNCTAGA--ACDAVN 972
CQC +G C HVSGAC C AG+ G CE CP G +G+ C C C +C ++
Sbjct: 323 TCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMS 382
Query: 973 GSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQA 1032
G C C G G C ETC YG C Q C+C NGA CD V G+C CAPG+ G C
Sbjct: 383 GECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTP 442
Query: 1033 CPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCL 1092
CP G YG NC C C+N C PV G C C GW G+ C C GC + CL
Sbjct: 443 CPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCL 502
Query: 1093 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPG 1152
NGG C+ G C C GW G+KC+ PC G +G CA+RC C CH TG CRC PG
Sbjct: 503 NGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPG 562
Query: 1153 FTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG 1212
++G C+ C G +G +C+ C C +C P G C CA G+ G +CQ+ C PG YG
Sbjct: 563 WSGVHCDSVCAEGRWGPNCSLPCYCKN-GASCSPDDGICECAPGFRGTTCQRICSPGFYG 621
Query: 1213 PGCEQLCG-CLNG-GSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC 1270
C Q C C++ G C TG C C GF G CN CP GRFG NC +C C C
Sbjct: 622 HRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTC 681
Query: 1271 DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRH 1330
+P+ +C C PG G C + CP +G C HTC+C NG C A +G C C GWTG +
Sbjct: 682 NPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLY 741
Query: 1331 CELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGL 1390
C CP G YG C L C C N + C+ +G C C GF G+ CE CP G +G GC+ +
Sbjct: 742 CTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQI 801
Query: 1391 CWCQHGAPCDPISGRCLCPAGFHGHFCER 1419
C C + + CD I+G C C G+ G C++
Sbjct: 802 CDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
Score = 689 bits (1777), Expect = 0.0
Identities = 310/748 (41%), Positives = 384/748 (51%), Gaps = 21/748 (2%)
Query: 598 CPKGYYGK------HCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS 651
C G+Y HC KC GRC C C+PG G C C +GP C+
Sbjct: 94 CCPGFYESGEMCVPHCADKCV---HGRCIAP-NTCQCEPGWGGTNCSSACDGDHWGPHCT 149
Query: 652 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS 711
CQC + C+ G+C C AGFRG RC+ CE G +G C Q C C G CD V+
Sbjct: 150 SRCQC--KNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVT 207
Query: 712 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCE 770
GEC RCP G+ G C CP G G C C C G CH VTG+C CP G G C
Sbjct: 208 GEC--RCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCG 265
Query: 771 ADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRC 830
CPEGR+G C + C C + CD TG C C PG+ G RCQD CP G YG C C
Sbjct: 266 QPCPEGRFGKNCSQECQ-CHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETC 324
Query: 831 SCANDGHCHPATGHCSCAPGWTGFSCQ-RACDTGHWGPDCSHPCNCSAGHG-SCDAISGL 888
C N G C+ +G C C G+ G C+ R C G +G C C C + SC +SG
Sbjct: 325 QCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGE 384
Query: 889 CLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACP 948
C C+ G+ G C + C G +G C+Q C CQ+GA CD V+G CTC G++G C CP
Sbjct: 385 CACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCP 444
Query: 949 AGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNG 1008
G +G++C S C C A C V+GSC C AG G C+ CP+ T+G C+ C C NG
Sbjct: 445 LGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNG 504
Query: 1009 ASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWA 1068
+C+ + G C CAPGW G C C G YG NC C C + C P +GHC C GW+
Sbjct: 505 GACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWS 564
Query: 1069 GLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEAC 1128
G+ C+ C C C NG C P G C C G+ G CQ C G++G C
Sbjct: 565 GVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRC 624
Query: 1129 AQRC-SCPPGAA-CHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHP 1186
+Q C C + CHH+TG C C PGFTG+ C + CP G FG++CA +C C N C+P
Sbjct: 625 SQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCT-NNGTCNP 683
Query: 1187 ATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCN 1246
+C C G+ G C Q CPP +GP C C C NG C A G C+C G+ G C
Sbjct: 684 IDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCT 743
Query: 1247 LTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1306
CP G +G +C +C C GA CD ++G C C G G CE+ CP +G GC C
Sbjct: 744 QRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD 803
Query: 1307 CRNGGLCHASNGSCSCGLGWTGRHCELA 1334
C N C G+C C GW G C+ A
Sbjct: 804 CLNNSTCDHITGTCYCSPGWKGARCDQA 831
Score = 675 bits (1742), Expect = 0.0
Identities = 314/778 (40%), Positives = 382/778 (49%), Gaps = 70/778 (8%)
Query: 804 CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTG 863
C PGF S ++C P C +C G C A C C PGW G +C ACD
Sbjct: 94 CCPGFYESG--EMCV-----PHCADKCV---HGRCI-APNTCQCEPGWGGTNCSSACDGD 142
Query: 864 HWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGA 923
HWGP C+ C C G C+ I+G C C AG+ G RCE +C QG +G C QRCQCQ+GA
Sbjct: 143 HWGPHCTSRCQCKNG-ALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGA 201
Query: 924 ACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRG 983
CDHV+G C CP G+ G FCE CP G G C C C G C V G C CP+G G
Sbjct: 202 TCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMG 261
Query: 984 PRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR 1043
C + CP +G NCSQ C C NG +CD GQCHC+PG+ G C CP G YG C
Sbjct: 262 TVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCA 321
Query: 1044 HSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPR-------DVRAGCRHSGGCLNGGL 1096
+C C NGG C VSG C C G+AG CE P D R C N
Sbjct: 322 ETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLE----NTHS 377
Query: 1097 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGS 1156
C P +G C C GW+G C C G++GEAC Q CSC GA C VTG C C PGF G
Sbjct: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGI 437
Query: 1157 GCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCE 1216
C CP G++G +C+ C C + C P G+C+C AG+HG C RCP G +G GC
Sbjct: 438 DCSTPCPLGTYGINCSSRCGCKND-AVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCN 496
Query: 1217 QLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT 1276
C CLNGG+C+ G C C G+ G C L C G +G NC C C C P TG
Sbjct: 497 LTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGH 556
Query: 1277 CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG-------------------------- 1310
C C PG +GV C+ C + R+G C C C+NG
Sbjct: 557 CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICS 616
Query: 1311 -------------------GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH 1351
G CH G C C G+TG C CP GR+G C C+C
Sbjct: 617 PGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCT 676
Query: 1352 NNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAG 1411
NN TC P +C+C PG+ G C PCPP G C C C +GA C G C C G
Sbjct: 677 NNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPG 736
Query: 1412 FHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP 1471
+ G +C + C G +G+ C C C GA CD ++G C C G G C C G +G
Sbjct: 737 WTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGY 796
Query: 1472 SCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASS 1529
C CDC + CD ++G C+C G+ G C + G + + SL++ S LPA S
Sbjct: 797 GCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLSRTST-ALPADS 853
Score = 669 bits (1727), Expect = 0.0
Identities = 300/736 (40%), Positives = 380/736 (51%), Gaps = 14/736 (1%)
Query: 517 GHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC 576
G C C D G C+ + C C GW G C+ C D +G +C+ C C+NG C
Sbjct: 102 GEMCVPHCADKCVHGRCIAP-NTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALC 160
Query: 577 DSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRF 636
+ +TGAC C G G CED C +G YG C ++C C N C + G C C PG G F
Sbjct: 161 NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAF 220
Query: 637 CHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCW 696
C CPP GP C + C C + C G CSC +G+ G C C G FG C
Sbjct: 221 CEDLCPPGKHGPQCEQRCPC--QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCS 278
Query: 697 QACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVT 755
Q C C G CD+ +G+C C G+ GE C ECPVGT+GV C+ +C C G C+ V+
Sbjct: 279 QECQCHNGGTCDAATGQC--HCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVS 336
Query: 756 GQCRCPPGRTGEDCEAD-CPEGRWGLGCQEICPA-CQHAARCDPETGACLCLPGFVGSRC 813
G C C G GE CEA CPEG +G+ C + CP ++ C P +G C C PG+ G C
Sbjct: 337 GACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYC 396
Query: 814 QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC 873
+ C G+YG +CQ CSC N C TG C+CAPG+ G C C G +G +CS C
Sbjct: 397 NETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRC 456
Query: 874 NCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACT 933
C C + G C C+AG+ G C +CP G +G GC CQC +G AC+ + G CT
Sbjct: 457 GCK-NDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCT 515
Query: 934 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAH 993
C GWRG CE C G +GL+C C+C+ C G C C G G C C
Sbjct: 516 CAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEG 575
Query: 994 TYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSC--LCQNG 1051
+G NCS C C NGASC P G C CAPG+ G +C + C G YG C +C +
Sbjct: 576 RWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSS 635
Query: 1052 GTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWT 1111
G C ++G C C G+ G C + C C C N G C+P C C GW
Sbjct: 636 GPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWI 695
Query: 1112 GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDC 1171
G C PC +G C C+C GA C G C+C PG+TG C Q CP G +G+DC
Sbjct: 696 GSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDC 755
Query: 1172 AQMCQCPGENPA-CHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAA 1230
A +CQC +N A C +G C+C G+ G C+Q+CP G YG GC Q+C CLN +CD
Sbjct: 756 ALICQC--QNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHI 813
Query: 1231 TGACRCPTGFLGTDCN 1246
TG C C G+ G C+
Sbjct: 814 TGTCYCSPGWKGARCD 829
Score = 668 bits (1724), Expect = 0.0
Identities = 302/753 (40%), Positives = 374/753 (49%), Gaps = 66/753 (8%)
Query: 759 RCPPG--RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV 816
+C PG +GE C C + C H P T C C PG+ G+ C
Sbjct: 93 QCCPGFYESGEMCVPHCAD------------KCVHGRCIAPNT--CQCEPGWGGTNCSSA 138
Query: 817 CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCS 876
C +GP C +RC C N C+P TG C CA G+ G+ C+ C+ G +G DC C C
Sbjct: 139 CDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ 198
Query: 877 AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPA 936
G +CD ++G C C GY G CE CP G GP CEQRC CQ+G C HV+G C+CP+
Sbjct: 199 NG-ATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPS 257
Query: 937 GWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
GW GT C CP G FG +C C C G CDA G C C G G RC + CP TYG
Sbjct: 258 GWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYG 317
Query: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSC-LQACPAGLYGDNCRHSCLC--QNGGT 1053
C++ C C NG C V G C C G+ G C + CP GLYG C C C +N +
Sbjct: 318 VLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS 377
Query: 1054 CDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGD 1113
C P+SG CAC GW+GL C + C P C+ C NG CD TG+C C G+ G
Sbjct: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGI 437
Query: 1114 KCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQ 1173
C +PC G +G C+ RC C A C V G+C C G+ G C CP G++G C
Sbjct: 438 DCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNL 497
Query: 1174 MCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA 1233
CQC AC+ GTC+CA G+ G C+ C G YG C + C C + C TG
Sbjct: 498 TCQCLNGG-ACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGH 556
Query: 1234 CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDP--------------------- 1272
CRC G+ G C+ C +GR+GPNC+ C C GA+C P
Sbjct: 557 CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICS 616
Query: 1273 ------------------------VTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1308
+TG C C PG G C CP RFG C C+C
Sbjct: 617 PGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCT 676
Query: 1309 NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPG 1368
N G C+ + SC C GW G C CPP +G C C+CHN + C G C+C PG
Sbjct: 677 NNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPG 736
Query: 1369 FYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGE 1428
+ G C CP GF+G C +C CQ+GA CD ISG+C C GF G CE+ C G++G
Sbjct: 737 WTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGY 796
Query: 1429 GCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCN 1461
GC Q CDC + CD +TG C C PG GA C+
Sbjct: 797 GCRQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
Score = 664 bits (1713), Expect = 0.0
Identities = 294/700 (42%), Positives = 361/700 (51%), Gaps = 14/700 (2%)
Query: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570
C D +G C+ C C+NG C C C G+ G C + C T+G +C C C
Sbjct: 139 CDGDHWGPHCTSRCQ-CKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQC 197
Query: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDP 630
QNG TCD VTG CRCPPG +G CED CP G +G C ++C C N G CH + G C C
Sbjct: 198 QNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPS 257
Query: 631 GLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY 690
G G C CP FG CS+ECQC T CD G C C G+ GERCQ EC +G
Sbjct: 258 GWMGTVCGQPCPEGRFGKNCSQECQCHNGGT--CDAATGQCHCSPGYTGERCQDECPVGT 315
Query: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDC-GQECPVGTFGVNCSSSCSC--- 746
+G C + C C G C VSG C C AGF GE C + CP G +G+ C C C
Sbjct: 316 YGVLCAETCQCVNGGKCYHVSGAC--LCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLE 373
Query: 747 GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLP 806
CH ++G+C C PG +G C C G +G CQ+IC +CQ+ A CD TG C C P
Sbjct: 374 NTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQIC-SCQNGADCDSVTGKCTCAP 432
Query: 807 GFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG 866
GF G C CP G YG +C +RC C ND C P G C+C GW G C C +G WG
Sbjct: 433 GFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG 492
Query: 867 PDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACD 926
C+ C C G G+C+ + G C C G+ G +CE C G +G C +RC C H C
Sbjct: 493 FGCNLTCQCLNG-GACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCH 551
Query: 927 HVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC 986
+G C C GW G C+ C G +G +C C C GA+C +G C C G RG C
Sbjct: 552 PTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTC 611
Query: 987 AETCPAHTYGHNCSQAC--ACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRH 1044
C YGH CSQ C + C + G C C PG+ G C + CP+G +G NC
Sbjct: 612 QRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAG 671
Query: 1045 SCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRC 1104
C C N GTC+P+ C C GW G C + C P C H+ C NG C + G C
Sbjct: 672 ICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGEC 731
Query: 1105 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPP 1164
C GWTG C C G++G+ CA C C GA C H++G C C GF G CEQ CP
Sbjct: 732 KCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPS 791
Query: 1165 GSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ 1204
G++G C Q+C C N C TGTC C+ G+ G C Q
Sbjct: 792 GTYGYGCRQICDCL-NNSTCDHITGTCYCSPGWKGARCDQ 830
Score = 610 bits (1573), Expect = e-174
Identities = 267/618 (43%), Positives = 329/618 (53%), Gaps = 10/618 (1%)
Query: 899 RCEQQCPQGHFGPG--CEQRC--QCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGL 954
R + QC G + G C C +C HG C C GW GT C AC +G
Sbjct: 89 RRKSQCCPGFYESGEMCVPHCADKCVHGRCI--APNTCQCEPGWGGTNCSSACDGDHWGP 146
Query: 955 DCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPV 1014
C S C C GA C+ + G+C C AG RG RC + C TYG++C Q C C NGA+CD V
Sbjct: 147 HCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHV 206
Query: 1015 HGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEK 1074
G+C C PG+ G C CP G +G C C CQNGG C V+G C+CP GW G C +
Sbjct: 207 TGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQ 266
Query: 1075 ECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSC 1134
C C C NGG CD TG+C C G+TG++CQ C G +G CA+ C C
Sbjct: 267 PCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQC 326
Query: 1135 PPGAACHHVTGACRCPPGFTGSGCE-QACPPGSFGEDCAQMCQCPGENP-ACHPATGTCS 1192
G C+HV+GAC C GF G CE + CP G +G C + C C EN +CHP +G C+
Sbjct: 327 VNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECA 386
Query: 1193 CAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQG 1252
C G+ G C + C PG YG C+Q+C C NG CD+ TG C C GF G DC+ CP G
Sbjct: 387 CKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLG 446
Query: 1253 RFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL 1312
+G NC+ CGC A C PV G+C C G GV C CP +G GC TC C NGG
Sbjct: 447 TYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGA 506
Query: 1313 CHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQ 1372
C+ +G+C+C GW G CEL C G YG C C C + C P TG CRC PG+ G
Sbjct: 507 CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGV 566
Query: 1373 ACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQ 1432
C+ C G G C C+C++GA C P G C C GF G C+R C PG +G C Q
Sbjct: 567 HCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQ 626
Query: 1433 RCD--CDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSG 1490
C PC +TGLC C PG +GA CN C G+FG +C C C C+P+
Sbjct: 627 TCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDR 686
Query: 1491 QCHCVDGYMGPTCREGGP 1508
C C G++G C + P
Sbjct: 687 SCQCYPGWIGSDCSQPCP 704
Score = 352 bits (904), Expect = 1e-96
Identities = 257/834 (30%), Positives = 330/834 (39%), Gaps = 128/834 (15%)
Query: 83 CVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPG 142
C H R Y YR T R +CC G+ E G + A C HG RC+
Sbjct: 69 CTRH--RVSYRTAYRHGEKTMYRRKSQCCPGFY----ESGEMCVPHCADKCVHG-RCI-- 119
Query: 143 SAQPCHCPPGFQGPRCQYDVD------ECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTD 196
+ C C PG+ G C D C T C++ + P + C C GFR
Sbjct: 120 APNTCQCEPGWGGTNCSSACDGDHWGPHC-TSRCQCKNGALCNPITGACHCAAGFRGWRC 178
Query: 197 SRTCL-------AINSCALGNGG-CQHHCVQLTITRHRCQCRPGF------QLQEDGRH- 241
C C NG C H C+C PG+ L G+H
Sbjct: 179 EDRCEQGTYGNDCHQRCQCQNGATCDH-------VTGECRCPPGYTGAFCEDLCPPGKHG 231
Query: 242 --CVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED--VDECAAGLAQCA 297
C +R PC N G C H V G C C G+ G+ C + + + QC
Sbjct: 232 PQCEQRCPCQN-GGVCHH----VTG--ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCH 284
Query: 298 HGCLNTQGSFKCVCHAGYELGADGRQCY------RIEMEIVNSCEANNGGCSHGCSHTSA 351
+G + +C C GY G +C + +C+ NGG C H S
Sbjct: 285 NGGTCDAATGQCHCSPGYT----GERCQDECPVGTYGVLCAETCQCVNGG---KCYHVSG 337
Query: 352 GPLCT------------CPRG-YELDTDQRTCIDVDDCADSPCCQQVCTNNPG--GYECG 396
LC CP G Y + D+R +++ C PG G C
Sbjct: 338 ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCN 397
Query: 397 --CYAGYRLSA--DGCGCEDVDECASSRGGCEHHCTNLAGSFQCS--CEAG-YRLH-EDR 448
C G+ A C C++ +C S G C C CS C G Y ++ R
Sbjct: 398 ETCSPGFYGEACQQICSCQNGADCDSVTGKCT--CAPGFKGIDCSTPCPLGTYGINCSSR 455
Query: 449 RGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEK 508
GC + +DG G H +
Sbjct: 456 CGCKN-DAVCSPVDGSCTCKA-------------------------------GWHGVDCS 483
Query: 509 FVCLDDSFGHDCSLTCDDCRNGGTCLLGLDG-CDCPEGWTGLICNETCPPDTFGKNCSFS 567
C ++G C+LTC C NGG C LDG C C GW G C C T+G NC+
Sbjct: 484 IRCPSGTWGFGCNLTC-QCLNGGACNT-LDGTCTCAPGWRGEKCELPCQDGTYGLNCAER 541
Query: 568 CSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACL 627
C C + C TG CRC PG SG +C+ C +G +G +C C C N C G C
Sbjct: 542 CDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICE 601
Query: 628 CDPGLYGRFCHLTCPPWAFGPGCSEEC-QCVQPHTQSCDKRDGSCSCKAGFRGERCQAEC 686
C PG G C C P +G CS+ C QCV + C G C C GF G C C
Sbjct: 602 CAPGFRGTTCQRICSPGFYGHRCSQTCPQCVH-SSGPCHHITGLCDCLPGFTGALCNEVC 660
Query: 687 ELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC 746
G FG C CTC C+ + C +C G+ G DC Q CP +G NC +C+C
Sbjct: 661 PSGRFGKNCAGICTCTNNGTCNPIDRSC--QCYPGWIGSDCSQPCPPAHWGPNCIHTCNC 718
Query: 747 -GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 805
GA C G+C+C PG TG C CP G +G C IC CQ+ A CD +G C C
Sbjct: 719 HNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALIC-QCQNGADCDHISGQCTCR 777
Query: 806 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRA 859
GF+G C+ CP+G YG C+ C C N+ C TG C C+PGW G C +A
Sbjct: 778 TGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQA 831
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 616 bits (1588), Expect = e-176
Identities = 278/664 (41%), Positives = 334/664 (50%), Gaps = 22/664 (3%)
Query: 804 CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTG 863
C GF SR G+ P C C G C A C C PGW G C C G
Sbjct: 90 CCHGFYESR-------GFCVPLCAQECV---HGRC-VAPNQCQCVPGWRGDDCSSECAPG 138
Query: 864 HWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGA 923
WGP C PC+C + SCD SG+C C +G P C Q C G++GP C+ RCQC HGA
Sbjct: 139 MWGPQCDKPCSCG-NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC-HGA 196
Query: 924 ACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRG 983
CD +GAC CPA G C+ +C G G C S +C G GSC CP G G
Sbjct: 197 PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMG 256
Query: 984 PRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR 1043
C+ CP +G NCSQ C C NG CD GQC CAPG+ G C + CP G +G +C
Sbjct: 257 TICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCA 316
Query: 1044 HSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCL----NGGLCDP 1099
+C C C P +G C C G+ G C P D G C + C P
Sbjct: 317 ETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCP-DGFYGLSCQAPCTCDREHSLSCHP 375
Query: 1100 HTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE 1159
G C C GW G C C + G C + C C G C +G C+C PG+TG C
Sbjct: 376 MNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCA 435
Query: 1160 QACPPGSFGEDCAQMCQCPGENP-ACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQL 1218
CPP ++G +C+ C C EN AC P G C C G+ +C CPPG +G C
Sbjct: 436 SLCPPDTYGVNCSARCSC--ENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNAS 493
Query: 1219 CGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCL 1278
C C + C TGAC C G+ G C L CP+G+FG C C C CDPV G C
Sbjct: 494 CQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQ 553
Query: 1279 CPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPG 1338
C G G RC CP+ +GV C +TC+C+NGG C NG+C C G+ G C+ +C PG
Sbjct: 554 CQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPG 613
Query: 1339 RYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAP 1398
RYG C + C C N+S C P+ GTC C G+ G C PCPPG G C C C HG
Sbjct: 614 RYGKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT 672
Query: 1399 CDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGA 1458
C P G C+CP G+ GH C GC G+FG C Q C C G C P TG C+CPPG SGA
Sbjct: 673 CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGA 732
Query: 1459 TCNL 1462
C +
Sbjct: 733 PCRI 736
Score = 607 bits (1564), Expect = e-173
Identities = 266/650 (40%), Positives = 342/650 (52%), Gaps = 21/650 (3%)
Query: 648 PGCSEEC---QCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVG 704
P C++EC +CV P+ C C G+RG+ C +EC G +GP C + C+C
Sbjct: 103 PLCAQECVHGRCVAPN---------QCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNN 153
Query: 705 VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGR 764
+CD SG C CP+G Q +C Q C G +G C C C GAPC TG C CP R
Sbjct: 154 SSCDPKSGVCS--CPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAER 211
Query: 765 TGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGP 824
TG C+ C +G G C +CQ+ G+C C PG++G+ C CP G++GP
Sbjct: 212 TGPSCDVSCSQGTSGFFCPST-HSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP 270
Query: 825 SCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDA 884
+C C C N G C TG C CAPG+TG C+ C G +G DC+ C+C A C
Sbjct: 271 NCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDC-APDARCFP 329
Query: 885 ISGLCLCEAGYVGPRC-EQQCPQGHFGPGCEQRCQC--QHGAACDHVSGACTCPAGWRGT 941
+G CLCE G+ G RC ++ CP G +G C+ C C +H +C ++G C+C GW G
Sbjct: 330 ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGL 389
Query: 942 FCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQ 1001
C +CP G C+ C C G C A +G C C G GP CA CP TYG NCS
Sbjct: 390 HCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSA 449
Query: 1002 ACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHC 1061
C+C N +C P+ G+C C GW +C CP G +G +C SC C + C P +G C
Sbjct: 450 RCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGAC 509
Query: 1062 ACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLR 1121
C GW G C+ C GC C + CDP GRC C AGW G +C C
Sbjct: 510 TCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPE 569
Query: 1122 GWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGEN 1181
G +G C+ C+C G C G C C PGF G C+++C PG +G+ C C+C +
Sbjct: 570 GLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVP-CKCANHS 628
Query: 1182 PACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
CHP+ GTC C AG+ GP C Q CPPG +G C Q C C +GG+C G+C CP G+
Sbjct: 629 -FCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWT 687
Query: 1242 GTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERG 1291
G C CP G FG NC+ C CG G C P TG C+CPPG +G C G
Sbjct: 688 GHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIG 737
Score = 598 bits (1542), Expect = e-170
Identities = 269/626 (42%), Positives = 320/626 (51%), Gaps = 15/626 (2%)
Query: 583 CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCP 642
C+C PG G +C C G +G C K C+C N C G C C GL C C
Sbjct: 120 CQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCT 179
Query: 643 PWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCP 702
P +GP C CQC H CD + G+C C A G C C G G C +C
Sbjct: 180 PGYYGPACQFRCQC---HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQ 236
Query: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCP 761
G + G C CP G+ G C CP G G NCS C C G C TGQCRC
Sbjct: 237 NGGVFQTPQGSCS--CPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCA 294
Query: 762 PGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQD-VCPAG 820
PG TG+ C +CP GR+G C E C C ARC P GACLC GF G RC D +CP G
Sbjct: 295 PGYTGDRCREECPVGRFGQDCAETCD-CAPDARCFPANGACLCEHGFTGDRCTDRLCPDG 353
Query: 821 WYGPSCQTRCSCANDGH--CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAG 878
+YG SCQ C+C + CHP G CSC PGW G C +C GP C C C G
Sbjct: 354 FYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHG 413
Query: 879 HGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGW 938
G C A SGLC C GY GP C CP +G C RC C++ AC + G C C GW
Sbjct: 414 -GVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGW 472
Query: 939 RGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHN 998
+ C CP G +G C ++C C A C G+C C G G C CP +G
Sbjct: 473 QRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEG 532
Query: 999 CSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVS 1058
C+ C C + CDPVHG+C C GWMG C +CP GL+G NC ++C C+NGGTC P +
Sbjct: 533 CASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPEN 592
Query: 1059 GHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSP 1118
G+C C G+ G +C++ C P C C N C P G C C AGWTG C P
Sbjct: 593 GNCVCAPGFRGPSCQRSCQPGRYGKRCVPC-KCANHSFCHPSNGTCYCLAGWTGPDCSQP 651
Query: 1119 CLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQC- 1177
C G +GE CAQ C C G CH G+C CP G+TG C + CP G+FG +C+Q CQC
Sbjct: 652 CPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCG 711
Query: 1178 PGENPACHPATGTCSCAAGYHGPSCQ 1203
PGE CHP TG C C G+ G C+
Sbjct: 712 PGEK--CHPETGACVCPPGHSGAPCR 735
Score = 588 bits (1516), Expect = e-167
Identities = 261/647 (40%), Positives = 331/647 (51%), Gaps = 14/647 (2%)
Query: 782 CQEICPA-CQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP 840
C +C C H P C C+PG+ G C C G +GP C CSC N+ C P
Sbjct: 101 CVPLCAQECVHGRCVAPNQ--CQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDP 158
Query: 841 ATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGS-CDAISGLCLCEAGYVGPR 899
+G CSC G +C + C G++GP C C C HG+ CD +G C C A GP
Sbjct: 159 KSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC---HGAPCDPQTGACFCPAERTGPS 215
Query: 900 CEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSA 959
C+ C QG G C CQ+G G+C+CP GW GT C CP GF G +C
Sbjct: 216 CDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQE 275
Query: 960 CNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCH 1019
C C G CD G C C G G RC E CP +G +C++ C C A C P +G C
Sbjct: 276 CRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACL 335
Query: 1020 CAPGWMGPSCL-QACPAGLYGDNCRHSCLC--QNGGTCDPVSGHCACPEGWAGLACEKEC 1076
C G+ G C + CP G YG +C+ C C ++ +C P++G C+C GWAGL C + C
Sbjct: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESC 395
Query: 1077 LPRDVRA-GCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCP 1135
P+D GC+ CL+GG+C +G C C G+TG C S C +G C+ RCSC
Sbjct: 396 -PQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCE 454
Query: 1136 PGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAA 1195
AC + G C C G+ C CPPG++G C CQC E C P TG C+C
Sbjct: 455 NAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHE-AVCSPQTGACTCTP 513
Query: 1196 GYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFG 1255
G+HG CQ CP G++G GC C C + CD G C+C G++G C+L+CP+G +G
Sbjct: 514 GWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG 573
Query: 1256 PNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1315
NC++ C C G C P G C+C PG G C+R C R+G C C C N CH
Sbjct: 574 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCV-PCKCANHSFCHP 632
Query: 1316 SNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
SNG+C C GWTG C CPPG +G C C CH+ TC P G+C C G+ G C
Sbjct: 633 SNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCL 692
Query: 1376 HPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCE 1422
CP G GA C C C G C P +G C+CP G G C G +
Sbjct: 693 EGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQ 739
Score = 565 bits (1457), Expect = e-161
Identities = 264/654 (40%), Positives = 328/654 (50%), Gaps = 24/654 (3%)
Query: 514 DSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG 573
+S G L +C +G + + C C GW G C+ C P +G C CSC N
Sbjct: 96 ESRGFCVPLCAQECVHGRC--VAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNN 153
Query: 574 GTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLY 633
+CD +G C CP G+ NC C GYYG C+ +C C + C GAC C
Sbjct: 154 SSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC-HGAPCDPQTGACFCPAERT 212
Query: 634 GRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDK------RDGSCSCKAGFRGERCQAECE 687
G C ++C G C P T SC GSCSC G+ G C C
Sbjct: 213 GPSCDVSCSQGTSGFFC--------PSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCP 264
Query: 688 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 747
G+ GP C Q C C G CD +G+C RC G+ G+ C +ECPVG FG +C+ +C C
Sbjct: 265 EGFHGPNCSQECRCHNGGLCDRFTGQC--RCAPGYTGDRCREECPVGRFGQDCAETCDCA 322
Query: 748 -GAPCHGVTGQCRCPPGRTGEDC-EADCPEGRWGLGCQEICPA-CQHAARCDPETGACLC 804
A C G C C G TG+ C + CP+G +GL CQ C +H+ C P G C C
Sbjct: 323 PDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSC 382
Query: 805 LPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGH 864
LPG+ G C + CP +GP CQ C C + G C +G C CAPG+TG C C
Sbjct: 383 LPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDT 442
Query: 865 WGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAA 924
+G +CS C+C +C I G C+C+ G+ C CP G +G C CQC H A
Sbjct: 443 YGVNCSARCSCENAI-ACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAV 501
Query: 925 CDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGP 984
C +GACTC GW G C+ CP G FG C S C+C CD V+G C C AG G
Sbjct: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
Query: 985 RCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRH 1044
RC +CP +G NCS C C NG +C P +G C CAPG+ GPSC ++C G YG C
Sbjct: 562 RCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRC-V 620
Query: 1045 SCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRC 1104
C C N C P +G C C GW G C + C P C + C +GG C P G C
Sbjct: 621 PCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSC 680
Query: 1105 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC 1158
+CP GWTG C C G FG C+Q C C PG CH TGAC CPPG +G+ C
Sbjct: 681 ICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPC 734
Score = 538 bits (1385), Expect = e-152
Identities = 239/618 (38%), Positives = 305/618 (49%), Gaps = 21/618 (3%)
Query: 894 GYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG 953
G+ P C Q+C G C QCQ C GWRG C C G +G
Sbjct: 99 GFCVPLCAQECVHGR----CVAPNQCQ-------------CVPGWRGDDCSSECAPGMWG 141
Query: 954 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDP 1013
C C+C ++CD +G C CP+G + P C + C YG C C C +GA CDP
Sbjct: 142 PQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC-HGAPCDP 200
Query: 1014 VHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE 1073
G C C GPSC +C G G C + CQNGG G C+CP GW G C
Sbjct: 201 QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICS 260
Query: 1074 KECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
C C C NGGLCD TG+C C G+TGD+C+ C G FG+ CA+ C
Sbjct: 261 LPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCD 320
Query: 1134 CPPGAACHHVTGACRCPPGFTGSGC-EQACPPGSFGEDCAQMCQCPGENP-ACHPATGTC 1191
C P A C GAC C GFTG C ++ CP G +G C C C E+ +CHP G C
Sbjct: 321 CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGEC 380
Query: 1192 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ 1251
SC G+ G C + CP +GPGC++ C CL+GG C A +G C+C G+ G C CP
Sbjct: 381 SCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPP 440
Query: 1252 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG 1311
+G NC+ C C AC P+ G C+C G C CP +G C +C C +
Sbjct: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEA 500
Query: 1312 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG 1371
+C G+C+C GW G HC+L CP G++G C C C ++ C+P G C+C G+ G
Sbjct: 501 VCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMG 560
Query: 1372 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH 1431
C CP G G C C C++G C P +G C+C GF G C+R C+PG +G+ C
Sbjct: 561 ARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRC- 619
Query: 1432 QRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ 1491
C C + C P G C C G +G C+ C G +G +C C C G C P G
Sbjct: 620 VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS 679
Query: 1492 CHCVDGYMGPTCREGGPL 1509
C C G+ G C EG PL
Sbjct: 680 CICPLGWTGHHCLEGCPL 697
Score = 490 bits (1261), Expect = e-138
Identities = 248/662 (37%), Positives = 308/662 (46%), Gaps = 42/662 (6%)
Query: 380 PCCQQVCTNNP--GGYECGCYAGYRLSADGCGCEDVDECASSRGG--CEHHCT--NLAG- 432
P C Q C + +C C G+R D C ECA G C+ C+ N +
Sbjct: 103 PLCAQECVHGRCVAPNQCQCVPGWR--GDDCS----SECAPGMWGPQCDKPCSCGNNSSC 156
Query: 433 ---SFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDD 489
S CSC +G + + C+P + P P D
Sbjct: 157 DPKSGVCSCPSGLQPPNCLQPCTP------------GYYGPACQFRCQCHGAPC---DPQ 201
Query: 490 VGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGL 549
GA AE G C + G C T C+NGG C CP GW G
Sbjct: 202 TGACFCPAERTGPSCDVS---CSQGTSGFFCPST-HSCQNGGVFQTPQGSCSCPPGWMGT 257
Query: 550 ICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRK 609
IC+ CP G NCS C C NGG CD TG CRC PG +G C + CP G +G+ C +
Sbjct: 258 ICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAE 317
Query: 610 KCNCANRGRCHRLYGACLCDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQPHTQSCDKRD 668
C+CA RC GACLC+ G G C CP +G C C C + H+ SC +
Sbjct: 318 TCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMN 377
Query: 669 GSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG 728
G CSC G+ G C C GPGC + C C G C + SG C +C G+ G C
Sbjct: 378 GECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLC--QCAPGYTGPHCA 435
Query: 729 QECPVGTFGVNCSSSCSCGGA-PCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICP 787
CP T+GVNCS+ CSC A C + G+C C G +C CP G WG C C
Sbjct: 436 SLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASC- 494
Query: 788 ACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSC 847
C H A C P+TGAC C PG+ G+ CQ CP G +G C +RC C + C P G C C
Sbjct: 495 QCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQC 554
Query: 848 APGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQG 907
GW G C +C G WG +CS+ C C G G+C +G C+C G+ GP C++ C G
Sbjct: 555 QAGWMGARCHLSCPEGLWGVNCSNTCTCKNG-GTCLPENGNCVCAPGFRGPSCQRSCQPG 613
Query: 908 HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAA 967
+G C C+C + + C +G C C AGW G C CP G +G +C C C G
Sbjct: 614 RYGKRCVP-CKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT 672
Query: 968 CDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGP 1027
C +GSC+CP G G C E CP T+G NCSQ C C G C P G C C PG G
Sbjct: 673 CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGA 732
Query: 1028 SC 1029
C
Sbjct: 733 PC 734
Score = 347 bits (890), Expect = 5e-95
Identities = 249/842 (29%), Positives = 315/842 (37%), Gaps = 151/842 (17%)
Query: 40 LQPGMPHVCAEQELTLVGRRQPCVQALSHTVPVWKAGCGWQAWCVGHERRTVYYMGYRQV 99
L P P+ C+ E ++ + S +P W+ + VY YRQV
Sbjct: 21 LNPSDPNTCSFWESFTTTTKESHSRPFS-LLPSEPCERPWEGPHTCPQPTVVYRTVYRQV 79
Query: 100 YTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQ 159
T+ R L+CC G+ + G C A C HG RCV + C C PG++G C
Sbjct: 80 VKTDHRQRLQCCHGFYES---RGFCVPLC-AQECVHG-RCV--APNQCQCVPGWRGDDCS 132
Query: 160 YDVDECRTHNGG--------CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNG 211
EC G C + P S +C C G + CL C G
Sbjct: 133 ---SECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQ----PPNCL--QPCTPGYY 183
Query: 212 G--CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCE 269
G CQ RCQC +PC + G+C C R C+
Sbjct: 184 GPACQF----------RCQCHG--------------APCDPQTGACF--CPAERTGPSCD 217
Query: 270 CHVGYQLAADGKACEDVDECA-AGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRI 327
V G C C G+ Q G C G +C G G C +
Sbjct: 218 --VSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQ- 274
Query: 328 EMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCT 387
C +NGG C + C C GY D C++ C
Sbjct: 275 ------ECRCHNGGL---CDRFTGQ--CRCAPGYTGDR----------------CREECP 307
Query: 388 NNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC--EH-----HCTNLA---GSFQCS 437
G +C A+ C C C + G C EH CT+ G + S
Sbjct: 308 VGRFGQDC---------AETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLS 358
Query: 438 CEAGYRL-HEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEE 496
C+A E C P+ L G G E
Sbjct: 359 CQAPCTCDREHSLSCHPMNGECSCLPGW-------------------------AGLHCNE 393
Query: 497 AELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCP 556
+ C D+ G C C C +GG C C C G+TG C CP
Sbjct: 394 S-------------CPQDTHGPGCQEHCL-CLHGGVCQATSGLCQCAPGYTGPHCASLCP 439
Query: 557 PDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANR 616
PDT+G NCS CSC+N C + G C C G NC CP G +G C C CA+
Sbjct: 440 PDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHE 499
Query: 617 GRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG 676
C GAC C PG +G C L CP FG GC+ C C H+ CD G C C+AG
Sbjct: 500 AVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDC--DHSDGCDPVHGRCQCQAG 557
Query: 677 FRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTF 736
+ G RC C G +G C CTC G C +G C C GF+G C + C G +
Sbjct: 558 WMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNC--VCAPGFRGPSCQRSCQPGRY 615
Query: 737 GVNCSSSCSCGG-APCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARC 795
G C C C + CH G C C G TG DC CP G WG C + C C H C
Sbjct: 616 GKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTC-QCHHGGTC 673
Query: 796 DPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFS 855
P+ G+C+C G+ G C + CP G +G +C C C CHP TG C C PG +G
Sbjct: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAP 733
Query: 856 CQ 857
C+
Sbjct: 734 CR 735
Score = 130 bits (326), Expect = 1e-29
Identities = 144/540 (26%), Positives = 184/540 (34%), Gaps = 104/540 (19%)
Query: 110 CCRGWM----QQPDEEGCLSAECSASL-CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDE 164
C GWM P EG CS C +GG C + Q C C PG+ G RC+ +E
Sbjct: 250 CPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQ-CRCAPGYTGDRCR---EE 305
Query: 165 CRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINS----------CALGNGG-- 212
C G C T C+C P R + CL + C G G
Sbjct: 306 CPVGRFG--QDCAET-----CDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLS 358
Query: 213 CQHHCV---QLTITRH----RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRG- 264
CQ C + +++ H C C PG+ G HC P C C + G
Sbjct: 359 CQAPCTCDREHSLSCHPMNGECSCLPGWA----GLHCNESCPQDTHGPGCQEHCLCLHGG 414
Query: 265 -----LARCECHVGYQLAADGKACEDVDECAAGLAQC----AHGCLNTQGSFKCVCHAGY 315
C+C GY C A+C A C G +CVC G+
Sbjct: 415 VCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG--ECVCKEGW 472
Query: 316 ELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDV-- 373
+ G C SC A+ C+H + CTC G+ Q C
Sbjct: 473 QRGNCSVPCPPGTWGF--SCNASCQ-CAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQF 529
Query: 374 -DDCADSPCCQQVCTNNPGGYECGCYAGY-----RLS----------ADGCGCEDVDECA 417
+ CA C +P C C AG+ LS ++ C C++ C
Sbjct: 530 GEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCL 589
Query: 418 SSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVL 477
G +C G SC+ + + C P + F P
Sbjct: 590 PENG----NCVCAPGFRGPSCQRSCQPGRYGKRCVPCK------CANHSFCHPSNGTCYC 639
Query: 478 QDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGL 537
G D + C +G +C+ TC C +GGTC
Sbjct: 640 LAGW--------TGPDCSQP-------------CPPGHWGENCAQTCQ-CHHGGTCHPQD 677
Query: 538 DGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDG 597
C CP GWTG C E CP TFG NCS C C G C TGAC CPPG SG C G
Sbjct: 678 GSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIG 737
Score = 35.0 bits (79), Expect = 0.56
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 110 CCRGWMQQPDEEGC----LSAECSASL-CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDE 164
C GW EGC A CS C G +C P + C CPPG G C+ + E
Sbjct: 682 CPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGA-CVCPPGHSGAPCRIGIQE 740
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 460 bits (1183), Expect = e-129
Identities = 457/1612 (28%), Positives = 596/1612 (36%), Gaps = 405/1612 (25%)
Query: 109 RCCRGWMQQPDEEGCLSAE-CSASLCFHGGRCVPGSAQP-CHCPPGFQGPRCQYDVDECR 166
RC GW + C A+ C+++ C +GG+C+P A CHCPP F GP C+ DV+EC
Sbjct: 128 RCPPGW----SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECG 183
Query: 167 THNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITR 224
G C+H C N GSY C C+ R + + NGG C
Sbjct: 184 QKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGT---CRPTGDVT 240
Query: 225 HRCQCRPGFQLQEDGRHCVRR-SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKAC 283
H C C PGF G++C C N C + V G+ C + G+ C
Sbjct: 241 HECACLPGF----TGQNCEENIDDCPGNN--CKNGGACVDGVNTYNCRCPPEWT--GQYC 292
Query: 284 -EDVDECAAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNG 340
EDVDEC C +G C NT G + CVC G+ G C E ++ C +
Sbjct: 293 TEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW----TGEDC----SENIDDCA--SA 342
Query: 341 GCSHG--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNP--GGYEC 395
C HG C A C CP G C D C +PC + C NP G C
Sbjct: 343 ACFHGATCHDRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAIC 398
Query: 396 GCYAGYRLSADGCGCEDVDECASSRGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCSP 453
C +GY + C +DVDEC+ CEH C N GSF+C C GY
Sbjct: 399 TCPSGY--TGPACS-QDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----------- 444
Query: 454 LEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLD 513
P ++D P + A D++ + + +C+
Sbjct: 445 -TGPRCEIDVNECVSNPCQNDATCLDQIGEF-----------------------QCICMP 480
Query: 514 DSFGHDCSLTCDDCR-----NGGTCLLGLD--GCDCPEGWTGLICNETCPPDTFGKNCSF 566
G C + D+C + G CL ++ C+CP G+TG +C + +
Sbjct: 481 GYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQ-------YDVDECA 533
Query: 567 SCSCQNGGTC--DSVTGACRCPPGVSGTNCE-----------------DG-------CPK 600
S C+NG C T C C G +GT+CE DG C
Sbjct: 534 STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRP 593
Query: 601 GYYGKHCRKKCN------CANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSE 652
GY G HC N C + G C A C C G G C + A P S
Sbjct: 594 GYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG 653
Query: 653 ECQCVQPHTQSCDKRDG-SCSCKAGFRGERCQA---ECELGYFGPGCWQACTCPVGVACD 708
C DK DG C+C+ G+ G C EC G C TC D
Sbjct: 654 TC---------LDKIDGYECACEPGYTGSMCNINIDECA----GNPCHNGGTCE-----D 695
Query: 709 SVSG-ECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG-QCRCPPGRTG 766
++G C RCP G+ C E C+S+ GA + G +C C PG +G
Sbjct: 696 GINGFTC--RCPEGYHDPTCLSEVN------ECNSNPCVHGACRDSLNGYKCDCDPGWSG 747
Query: 767 EDCEADCPEGRWGLGCQEICPACQHAARCDPETG--ACLCLPGFVGSRCQ---------- 814
+C+ + E C+ C + C T C C GF G CQ
Sbjct: 748 TNCDINNNE------CES--NPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNP 799
Query: 815 ---------DV------CPAGWYGPSCQTRCS------CANDGHCHPATGH----CSCAP 849
DV C + G +C+ + C N G C + + C C
Sbjct: 800 CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPT 859
Query: 850 GWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHF 909
GW G +C+ + P C H +C HG C C+AGY G CE
Sbjct: 860 GWQGQTCEVDINECVLSP-CRHGASCQNTHGGY-----RCHCQAGYSGRNCETDIDDCRP 913
Query: 910 GPGCEQRCQCQHGAAC-DHVSGA-CTCPAGWRGTFCE---HACPAGFFGLDCRSACNCTA 964
P C +G +C D ++ A C C G+RGTFCE + C + CR+ NCT
Sbjct: 914 NP-------CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD----PCRNGANCT- 961
Query: 965 GAACDAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPG 1023
D V+ +C CPAG G C P +C+++ +CFNG + C G
Sbjct: 962 ----DCVDSYTCTCPAGFSGIHCENNTP------DCTES-SCFNGGT---------CVDG 1001
Query: 1024 WMGPSCLQACPAGLYGDNCRH------SCLCQNGGTCDPVSG--HCACPEGWAGLACEKE 1075
+CL CP G G C+H S C +GGTC G C CP+G+ G C+
Sbjct: 1002 INSFTCL--CPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ-- 1057
Query: 1076 CLPRDVRAGCRHSGGCLNGGLC-DPHTG-RCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
++ C S C NGG C HT RC CP+GWTG C P + E AQR
Sbjct: 1058 ----NLVHWC-DSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVS---CEVAAQRQG 1109
Query: 1134 CPPGAACHH--------VTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPA-C 1184
C H T CRC G+TGS CE ++C+ P +N A C
Sbjct: 1110 VDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLV------DECS---PSPCQNGATC 1160
Query: 1185 HPATG--TCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSC--DAATGACRCPTGF 1240
G +C C AGYHG +C + P C NGG+C T C CP G
Sbjct: 1161 TDYLGGYSCKCVAGYHGVNCSEEIDECLSHP-------CQNGGTCLDLPNTYKCSCPRGT 1213
Query: 1241 LGT-------DCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG-TCLCPPGRAGVRCERGC 1292
G DCN P C + G D V G +C CPPG G RCE
Sbjct: 1214 QGVHCEINVDDCNPPVDPVSRSPKCFN-----NGTCVDQVGGYSCTCPPGFVGERCEGDV 1268
Query: 1293 PQNRFGVGCEHTCSCRNGGLC--HASNGSCSCGLGWTGRHCE------------------ 1332
+ + C R C ++ C C G TGR CE
Sbjct: 1269 NE-----CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCA 1323
Query: 1333 ----------LACPPGRYGAACHLEC------SCHNNSTC--EPATGTCRCGPGFYGQAC 1374
CP G GA C + C N TC P + TC C F G C
Sbjct: 1324 VASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC 1383
Query: 1375 EHPCPPGFHGAGCQGLCWCQHGAPCDPISG----RCLCPAGFHGHFCE-----------R 1419
+ P + C G C + C+P S RCLCPA F+G C R
Sbjct: 1384 QFPA-----SSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGR 1438
Query: 1420 GCEPGSFGEGCH-QRCDCD-GGAPCDPVTGLCLCPPGRSGATCNLD-------------C 1464
P E C C D G C C G G C+L+ C
Sbjct: 1439 DIPPPLIEEACELPECQEDAGNKVCSLQCNNHAC--GWDGGDCSLNFNDPWKNCTQSLQC 1496
Query: 1465 RRGQFGPSCTLHCDCGG----GADCDPVSGQC------HCVDGYMGPTCREG 1506
+ C C+ G G DC GQC +C D + C +G
Sbjct: 1497 WKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQG 1548
Score = 365 bits (936), Expect = e-100
Identities = 412/1533 (26%), Positives = 541/1533 (35%), Gaps = 398/1533 (25%)
Query: 276 LAADGKACEDVDECAAGLAQCAHG--CLNTQGSFKCVCHAGYELGA---DGRQCYRIEME 330
LAA G C E C +G C G+ CVC + +G D C +
Sbjct: 17 LAARGPRCSQPGET------CLNGGKCEAANGTEACVCGGAF-VGPRCQDPNPCLSTPCK 69
Query: 331 IVNSCEA--NNGGCSHGCSHTS--AGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVC 386
+C G + CS +GPLC P LD C+ + C + C +
Sbjct: 70 NAGTCHVVDRRGVADYACSCALGFSGPLCLTP----LDN---ACL-TNPCRNGGTCDLLT 121
Query: 387 TNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYR--- 443
Y+C C G+ G C+ D CAS+ C S+ C C +
Sbjct: 122 LTE---YKCRCPPGW----SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPT 174
Query: 444 LHEDRRGCSPLEEPMVDLDG-----ELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAE 498
+D C ++P + G E+ R + + + +
Sbjct: 175 CRQDVNECG--QKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGT 232
Query: 499 LRGEHTLTEKFVCLDDSFGHDCSLTCDDC-----RNGGTCLLGLDGCDCPEGWTGLICNE 553
R +T + CL G +C DDC +NGG C+ G++ +C
Sbjct: 233 CRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNC----------- 281
Query: 554 TCPPDTFGKNCSFSC--------SCQNGGTCDSVTGA--CRCPPGVSGTNCE---DGCPK 600
CPP+ G+ C+ +CQNGGTC + G C C G +G +C D C
Sbjct: 282 RCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCAS 341
Query: 601 G--YYGKHCRKK-----CNCANRGR----CHRLYGACLCDPGLYGRFCHL---------T 640
++G C + C C + GR CH L AC+ +P G C T
Sbjct: 342 AACFHGATCHDRVASFYCECPH-GRTGLLCH-LNDACISNPCNEGSNCDTNPVNGKAICT 399
Query: 641 CPPWAFGPGCSE---ECQC-VQP--HTQSCDKRDGS--CSCKAGFRGERCQAECELGYFG 692
CP GP CS+ EC P H C GS C C G+ G RC+ +
Sbjct: 400 CPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSN 459
Query: 693 PGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG---QECPVGTFGVNCSSSCSCGGA 749
P C C GE C G++G C EC SS C G
Sbjct: 460 P-------CQNDATCLDQIGEFQCICMPGYEGVHCEVNTDEC--------ASSPCLHNGR 504
Query: 750 PCHGVTG-QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARC--DPETGACLCLP 806
+ QC CP G TG C+ D E C C++ A+C P T C+C
Sbjct: 505 CLDKINEFQCECPTGFTGHLCQYDVDE------CAST--PCKNGAKCLDGPNTYTCVCTE 556
Query: 807 GFVGSRCQ---DVC-PAGWYGPSCQT-----RCSCA---NDGHCHPATGHCSCAPGWTGF 854
G+ G+ C+ D C P + SC+ C C HC CS P G
Sbjct: 557 GYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGG 616
Query: 855 SCQRA-------CDTGHWGPDC--------SHPCNCSAGHGSC-DAISGL-CLCEAGYVG 897
+CQ C G GP+C S PC+ G+C D I G C CE GY G
Sbjct: 617 TCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDS----GTCLDKIDGYECACEPGYTG 672
Query: 898 PRCEQ-------------------------QCPQGHFGPGCEQRCQ------CQHGAACD 926
C +CP+G+ P C C HGA D
Sbjct: 673 SMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRD 732
Query: 927 HVSG-ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS-CLCPAGRRGP 984
++G C C GW GT C+ +C S G D +G C C G GP
Sbjct: 733 SLNGYKCDCDPGWSGTNCD------INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGP 786
Query: 985 RCAETCPAHTYGHNCSQACACFNGASC-DPVHG-QCHCAPGWMGPSC---LQACPAGLYG 1039
C T + C+ C N +C D V G +C+C + G +C L C
Sbjct: 787 NC------QTNINECASN-PCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSP-- 837
Query: 1040 DNCRHSCLCQNGGTC----DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGG 1095
C+NGG C D S C CP GW G CE + + V + CRH C N
Sbjct: 838 --------CRNGGECRQSEDYESFSCVCPTGWQGQTCEVD-INECVLSPCRHGASCQN-- 886
Query: 1096 LCDPHTG-RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFT 1154
H G RC C AG++G C++ + C SC G T C C PGF
Sbjct: 887 ---THGGYRCHCQAGYSGRNCETD-IDDCRPNPCHNGGSCTDGIN----TAFCDCLPGFR 938
Query: 1155 GSGCEQ--------ACPPGSFGEDCAQM--CQCPGENPACHPATGTCSCAAG--YHGPSC 1202
G+ CE+ C G+ DC C CP H T C ++G +C
Sbjct: 939 GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC 998
Query: 1203 QQR-------CPPGRYGPGCEQLCG------CLNGGSCDAATGACRCPTGFLGTDCNLTC 1249
CPPG G C+ CL+GG+C G+ RC TC
Sbjct: 999 VDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRC-----------TC 1047
Query: 1250 PQGRFGPNC---THVCG---CGQGAAC--DPVTGTCLCPPGRAGVRCER---GCPQNRFG 1298
PQG GPNC H C C G C C CP G G+ C+ C
Sbjct: 1048 PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQR 1107
Query: 1299 VGCEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECS---CHNN 1353
G + C++GGLC + + C C G+TG +CE ECS C N
Sbjct: 1108 QGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD----------ECSPSPCQNG 1157
Query: 1354 STCEPATG--TCRCGPGFYGQACE--------HPCPPGFHGAGCQGL-----CWCQHGA- 1397
+TC G +C+C G++G C HPC +G C L C C G
Sbjct: 1158 ATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ---NGGTCLDLPNTYKCSCPRGTQ 1214
Query: 1398 -------------PCDPISGR-----------------CLCPAGFHGHFCE--------- 1418
P DP+S C CP GF G CE
Sbjct: 1215 GVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSN 1274
Query: 1419 ----RG--------------CEPGSFGEGCHQRCD------CDGGAPCDPVTG-----LC 1449
RG C G G C + C G C + +C
Sbjct: 1275 PCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFIC 1334
Query: 1450 LCPPGRSGATCNLDCRRGQFGPSC-TLHCDCGGGADCDPVSGQCHCVDGYMGPTCR-EGG 1507
CP G GATC D R +C +L C GG P S C C+ + GP C+
Sbjct: 1335 KCPAGFEGATCENDAR------TCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPAS 1388
Query: 1508 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPAR 1540
L NP QG+ P S P R PA+
Sbjct: 1389 SPCLGGNPCYNQGTCE--PTSESPFYRCLCPAK 1419
Score = 172 bits (435), Expect = 3e-42
Identities = 153/512 (29%), Positives = 191/512 (37%), Gaps = 109/512 (21%)
Query: 1029 CLQACPA-GLYGDNCRHSC-LCQNGGTCDPVSGH--CACPEGWAGLACE--KECLPRDVR 1082
CL PA G C C NGG C+ +G C C + G C+ CL
Sbjct: 10 CLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCL----- 64
Query: 1083 AGCRHSGGCLNGGLCDPHTGR------CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPP 1136
S C N G C R C C G++G C +P AC C
Sbjct: 65 -----STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTP-----LDNACLTN-PCRN 113
Query: 1137 GAACHHVTGA---CRCPPGFTGSGCEQACPPGSFGEDCAQMCQC-PGENPACHPATGTCS 1192
G C +T CRCPPG++G C+QA P S CA QC P E A+ C
Sbjct: 114 GGTCDLLTLTEYKCRCPPGWSGKSCQQADPCAS--NPCANGGQCLPFE------ASYICH 165
Query: 1193 CAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQG 1252
C +HGP+C+Q PG C +GG+C G+ RC C
Sbjct: 166 CPPSFHGPTCRQDVNECGQKPGL-----CRHGGTCHNEVGSYRC-----------VCRAT 209
Query: 1253 RFGPNCTH---VCG---CGQGAACDP---VTGTCLCPPGRAGVRCERG---CPQNRFGVG 1300
GPNC C C G C P VT C C PG G CE CP N
Sbjct: 210 HTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGN----- 264
Query: 1301 CEHTCSCRNGGLC--HASNGSCSCGLGWTGRHCELACPPGRYGAACHL-ECSCHNNSTCE 1357
+C+NGG C + +C C WTG++C C L +C N TC
Sbjct: 265 -----NCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVD------ECQLMPNACQNGGTCH 313
Query: 1358 PATG--TCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDP--ISGRCLCPAGFH 1413
G C C G+ G+ C A C HGA C S C CP G
Sbjct: 314 NTHGGYNCVCVNGWTGEDCSENIDDCASAA-------CFHGATCHDRVASFYCECPHGRT 366
Query: 1414 GHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGP 1471
G C C++ +CD +PV G +C CP G +G C+ D G
Sbjct: 367 GLLCH--LNDACISNPCNEGSNCD----TNPVNGKAICTCPSGYTGPACSQDVDECSLGA 420
Query: 1472 SCTLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1503
+ C+ G S +C C+ GY GP C
Sbjct: 421 N---PCEHAGKCINTLGSFECQCLQGYTGPRC 449
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 435 bits (1119), Expect = e-121
Identities = 452/1561 (28%), Positives = 568/1561 (36%), Gaps = 343/1561 (21%)
Query: 15 VLALVLLLLPAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQPCV-------QALS 67
V AL LLLL A P GA+ PP G P + L R C+ +
Sbjct: 24 VRALPLLLLLAGP-GAAAPP-----CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ 77
Query: 68 HTVPVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAE 127
P C + C V AR RC RG+ + PD L
Sbjct: 78 LEDPCHSGPCAGRGVCQS------------SVVAGTARFSCRCPRGF-RGPDCS--LPDP 122
Query: 128 CSASLCFHGGRCV--PGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH--RCVNTPGSY 183
C +S C HG RC P C CPPG+QG C+ DVDECR C+H C+NTPGS+
Sbjct: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRV-GEPCRHGGTCLNTPGSF 181
Query: 184 LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC- 242
C+C G+ + NGG C Q + C C PGF +G++C
Sbjct: 182 RCQCPAGYTGPLCENPAVPCAPSPCRNGGT---CRQSGDLTYDCACLPGF----EGQNCE 234
Query: 243 VRRSPCANRNGSCMHRCQVVRGL--ARCECHVGYQLAADGKAC-EDVDECAAGLAQCAHG 299
V C C++ V G+ C+C + G+ C EDVDEC C +G
Sbjct: 235 VNVDDCPGHR--CLNGGTCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNG 288
Query: 300 --CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLC 355
C NT G CVC G+ G C + N + C HG C A C
Sbjct: 289 GTCFNTLGGHSCVCVNGW----TGESCSQ------NIDDCATAVCFHGATCHDRVASFYC 338
Query: 356 TCPRGYELDTDQRTCIDVDDCADSPCCQQ-VCTNNP--GGYECGCYAGYRLSADGCGCED 412
CP G C D C +PC + +C NP G C C G+ G +D
Sbjct: 339 ACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF---TGGACDQD 391
Query: 413 VDECASSRGGCEH--HCTNLAGSFQCSCEAGY---RLHEDRRGC--SPLEEPMVDLDGEL 465
VDEC+ CEH C N GSF C C GY R D C P LD
Sbjct: 392 VDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIG 451
Query: 466 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRG----EHTLTEKFVCLDDSFGHDCS 521
F + + + D+ + + G + C G C
Sbjct: 452 QFT------CICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 505
Query: 522 LTCDD-----CRNGGTCLLGLDG--CDCPEGWTGLICN---ETCPPDTFGKN------CS 565
L D+ CRNG C+ DG C C EG+ G +C+ + C PD S
Sbjct: 506 LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIAS 565
Query: 566 FSCSCQNGGT---CDSVTGACRCPPGVSGTNCED-------GCPKGYYGKHCRKKC-NCA 614
FSC+C G T C+S CR P G C D CP G G +C +CA
Sbjct: 566 FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCA 625
Query: 615 NR----GRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQ---------- 658
+ G C C+C PG G C++ A P C E CV
Sbjct: 626 SNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSP-CGEGGSCVDGENGFRCLCP 684
Query: 659 ---------PHTQSCDKRDGSCS---CKAGFRGERCQAECELGYFGPGCWQACTCPVGVA 706
P + C CS C G RC CE G+ GP C Q+ A
Sbjct: 685 PGSLPPLCLPPSHPCAHE--PCSHGICYDAPGGFRC--VCEPGWSGPRCSQSLARD---A 737
Query: 707 CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPC-HGVTGQCRCPPGRT 765
C+S G C + G C CP G G C C PC HG G+C PG+
Sbjct: 738 CESQPCRAGGTCSSDGMGFHC--TCPPGVQGRQCELLSPCTPNPCEHG--GRCESAPGQL 793
Query: 766 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS 825
CP+G G CQ+ C A C P G C L G C G+ GPS
Sbjct: 794 P---VCSCPQGWQGPRCQQDVDECAGPAPCGPH-GICTNLAGSFSCTCH----GGYTGPS 845
Query: 826 CQTRCS------CANDGHCHPATG--HCSCAPGWTGFSCQR------------------- 858
C + C N G C G CSC PG+ G C R
Sbjct: 846 CDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHV 905
Query: 859 -----ACDTGHWG-------PDCSHPCNCSAGHGSCDAISGL-CLCEAGYVGPRCEQQ-- 903
C G+ G PDCS P +C G D ++ CLC GY G C+ +
Sbjct: 906 ASFTCTCPPGYGGFHCEQDLPDCS-PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEAD 964
Query: 904 -----------------------CPQGHFGPGCE------QRCQCQHGAACDHVSGACTC 934
C + GP C+ R CQ+G C C C
Sbjct: 965 PCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLC 1024
Query: 935 PAGWRGTFCEHACPAGFFGLDCRSACN---------CTAGAACDAVNGS--CLCPAGRRG 983
P GW G C+ L CR A C AG C + S C+CP GR G
Sbjct: 1025 PPGWSGRLCD------IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTG 1078
Query: 984 PRCAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDN 1041
C + + A C +G +C G C C PG+ G +C D
Sbjct: 1079 SHCEQEV-------DPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV------DE 1125
Query: 1042 CRHSCLCQNGGTC-DPVSGH-CACPEGWAGLAC---EKEC---LPRDVRAGCRHSGGCLN 1093
C S CQ+GG+C D V+ + C+CP G G+ C E +C P D C H+G C++
Sbjct: 1126 CA-SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVD 1184
Query: 1094 --GGLCDPHTGRCLCPAGWTGDKCQ---SPCLRGWFGEACAQRCSCPPGAACHHVTGACR 1148
GG RC CP G+TG +C+ + C G A + C PG C
Sbjct: 1185 LVGGF------RCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFR-----CL 1233
Query: 1149 CPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATG-------TCSCAAGYHGPS 1201
C GF+G C+ P +Q CQ G+ C P+ G TC CA + GP
Sbjct: 1234 CHAGFSGPRCQTVLSPCE-----SQPCQHGGQ---CRPSPGPGGGLTFTCHCAQPFWGPR 1285
Query: 1202 CQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNL--TCPQGRFGPN 1257
C+ R C +L C G C C CP G G C P G +
Sbjct: 1286 CE------RVARSCREL-QCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNAS 1338
Query: 1258 CTHVCGCGQGAACDPVT----GTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLC 1313
C C G +C P C C G G RCE P V E C C
Sbjct: 1339 CA-AAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE--APAAAPEVSEEPRCP---RAAC 1392
Query: 1314 HASNGSCSC-------GLGWTGRHCELAC-PPGRYGAACHLEC-SCHNNSTCEPATGTCR 1364
A G C G GW G C L+ P R A L+C NNS C+PA +
Sbjct: 1393 QAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEA--LQCWRLFNNSRCDPACSSPA 1450
Query: 1365 C 1365
C
Sbjct: 1451 C 1451
Score = 395 bits (1014), Expect = e-109
Identities = 407/1450 (28%), Positives = 507/1450 (34%), Gaps = 350/1450 (24%)
Query: 296 CAHGCLNTQGSFK---CVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAG 352
CA+G TQ + C+C G+ G +C ++E + A G C +A
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWV----GERC-QLEDPCHSGPCAGRGVCQSSVVAGTAR 103
Query: 353 PLCTCPRGYELDTDQRTCIDVDDCADSPCCQQV-CTNNPGG-YECGCYAGYRLSADGCGC 410
C CPRG+ C D C SPC C+ P G + C C GY+ G C
Sbjct: 104 FSCRCPRGFR----GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ----GRSC 155
Query: 411 E-DVDECASSRGGCEHH--CTNLAGSFQCSCEAGYRLHEDRRGCSPL-EEPMVDLDGELP 466
DVDEC C H C N GSF+C C AGY PL E P V
Sbjct: 156 RSDVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYT--------GPLCENPAVPC----- 201
Query: 467 FVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDD 526
P P R LT CL G +C + DD
Sbjct: 202 --APSPC--------------------RNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDD 239
Query: 527 -----CRNGGTCLLGLD--GCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSV 579
C NGGTC+ G++ C CP WTG C E N +C NGGTC +
Sbjct: 240 CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN-----ACHNGGTCFNT 294
Query: 580 TG--ACRCPPGVSGTNCE---DGCPKG--YYGKHCRKK-------CNCANRGRCHRLYGA 625
G +C C G +G +C D C ++G C + C G L A
Sbjct: 295 LGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDA 354
Query: 626 CLCDPGLYGRFCH---------LTCPPWAFGPGCS---EECQC-VQP--HTQSCDKRDGS 670
C+ +P C TCPP G C +EC P H C GS
Sbjct: 355 CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS 414
Query: 671 --CSCKAGFRGERCQAECELGYFGPGCWQACTC--PVG-VACDSVSGECGKRCPAGF--- 722
C C G+ G RC+ + GP C TC +G C ++G G C
Sbjct: 415 FLCQCGRGYTGPRCETDVNECLSGP-CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDEC 473
Query: 723 QGEDC--GQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDC-------EADC 773
Q C G C G +C+ G+ C +C P R G C E C
Sbjct: 474 QSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRC 533
Query: 774 PEGRWGLGCQEICPACQ----HAARC--DPETGACLCLPGFVGSRCQDV----------- 816
EG G C C H RC + +C C PG+ G+RC+
Sbjct: 534 AEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRH 593
Query: 817 --------------CPAGWYGPSCQTRC-SCAND----GHCHPATGH--CSCAPGWTGFS 855
CP+G G +C+ CA++ G C C C PG+TG
Sbjct: 594 GGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPL 653
Query: 856 C-------------------------QRACDTGHWGPDC---SHPC-NCSAGHGSC-DAI 885
C + C G P C SHPC + HG C DA
Sbjct: 654 CNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAP 713
Query: 886 SGL-CLCEAGYVGPRCEQQ---------------------------CPQGHFGPGCE--Q 915
G C+CE G+ GPRC Q CP G G CE
Sbjct: 714 GGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLS 773
Query: 916 RC---QCQHGAACDHVSG---ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACD 969
C C+HG C+ G C+CP GW+G C+ +C C C
Sbjct: 774 PCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVD------ECAGPAPCGPHGICT 827
Query: 970 AVNG--SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGWM 1025
+ G SC C G GP C + N C NG SC G C C PG+
Sbjct: 828 NLAGSFSCTCHGGYTGPSCDQDI-------NDCDPNPCLNGGSCQDGVGSFSCSCLPGFA 880
Query: 1026 GPSCLQ------------------------ACPAGLYGDNCRHS------CLCQNGGTC- 1054
GP C + CP G G +C C NGGTC
Sbjct: 881 GPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCV 940
Query: 1055 DPV-SGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCD-PHTG-RCLCPAGWT 1111
D V S C C G+ G C+ E P C S CL+GG+C H G RC C +T
Sbjct: 941 DGVNSFSCLCRPGYTGAHCQHEADP------CL-SRPCLHGGVCSAAHPGFRCTCLESFT 993
Query: 1112 GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPP-----GS 1166
G +CQ+ L W R C G C C CPPG++G C+ P
Sbjct: 994 GPQCQT--LVDW-----CSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQ 1046
Query: 1167 FGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGS 1226
G Q+CQ G+ ++ C C G G C+Q P P C +GG+
Sbjct: 1047 IGVRLEQLCQAGGQ-CVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQP-------CQHGGT 1098
Query: 1227 CDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLCPPG 1282
C G C C G+ G +C + P C G +C + C CPPG
Sbjct: 1099 CRGYMGGYMCECLPGYNGDNCEDDVDECASQP-------CQHGGSCIDLVARYLCSCPPG 1151
Query: 1283 RAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRY 1340
GV CE G + C + G C G C+C G+TG CE R
Sbjct: 1152 TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRS 1211
Query: 1341 GAACHLECSCHNNSTCEPATG--TCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAP 1398
G ACH + H + G C C GF G C+ P C+ CQHG
Sbjct: 1212 G-ACH---AAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSP------CESQP-CQHGGQ 1260
Query: 1399 CDPISG-------RCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCD--PVTGLC 1449
C P G C C F G CER C + C G PC P C
Sbjct: 1261 CRPSPGPGGGLTFTCHCAQPFWGPRCER------VARSCRE-LQCPVGVPCQQTPRGPRC 1313
Query: 1450 LCPPGRSGATCNL--DCRRGQFGPSCTLHCDCGGGADCDPVS----GQCHCVDGYMGPTC 1503
CPPG SG +C G SC C G C P +C C G+ GP C
Sbjct: 1314 ACPPGLSGPSCRSFPGSPPGASNASCAA-APCLHGGSCRPAPLAPFFRCACAQGWTGPRC 1372
Query: 1504 REGGPLRLPE 1513
P PE
Sbjct: 1373 E--APAAAPE 1380
Score = 349 bits (896), Expect = 1e-95
Identities = 380/1352 (28%), Positives = 477/1352 (35%), Gaps = 359/1352 (26%)
Query: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQ-----------------------P 146
C GW + + +C+ ++CFHG C A P
Sbjct: 302 CVNGWTGESCSQNI--DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNP 359
Query: 147 CH-----------------CPPGFQGPRCQYDVDECRTHNGGCQH--RCVNTPGSYLCEC 187
CH CPPGF G C DVDEC C+H RCVNT GS+LC+C
Sbjct: 360 CHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 419
Query: 188 KPGF---RLHTDSRTCLAINSCALGNGGCQHHCVQL-TITRHRCQCRPGFQLQEDGRHC- 242
G+ R TD CL +G C++ L I + C C GF G +C
Sbjct: 420 GRGYTGPRCETDVNECL--------SGPCRNQATCLDRIGQFTCICMAGF----TGTYCE 467
Query: 243 -----VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGLAQC 296
+ SPC N G C R V G + C C G+ G C+ DVDECA+ +
Sbjct: 468 VDIDECQSSPCVN-GGVCKDR---VNGFS-CTCPSGF----SGSTCQLDVDECASTPCRN 518
Query: 297 AHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLC 355
C++ ++C C G+E G C R N + + C HG C A C
Sbjct: 519 GAKCVDQPDGYECRCAEGFE----GTLCDR------NVDDCSPDPCHHGRCVDGIASFSC 568
Query: 356 TCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECGCYAGYRLSADGCGCE-DV 413
C GY T R VD+C PC C + Y C C +G G CE ++
Sbjct: 569 ACAPGY---TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG----TTGVNCEVNI 621
Query: 414 DECASSRGGCEHH-CTNLAGSFQCSCEAGY-----RLHEDRRGCSPLEEPMVDLDGELPF 467
D+CAS+ C C + + C C+ G+ + + SP E +DGE F
Sbjct: 622 DDCASN--PCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGF 679
Query: 468 VRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDC 527
P LP L H +C D G C C+
Sbjct: 680 RCLCP-----PGSLPPLCLPPSHPC---------AHEPCSHGICYDAPGGFRC--VCEPG 723
Query: 528 RNGGTC--LLGLDGCD---CPEGWT----GLICNETCPPDTFGKNCSF--SCS---CQNG 573
+G C L D C+ C G T G+ + TCPP G+ C C+ C++G
Sbjct: 724 WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHG 783
Query: 574 GTCDSVTG---ACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDP 630
G C+S G C CP G G C+ + C C G C L G+ C
Sbjct: 784 GRCESAPGQLPVCSCPQGWQGPRCQQDVDE------CAGPAPCGPHGICTNLAGSFSC-- 835
Query: 631 GLYGRFCHLTCPPWAFGPGCSEECQCVQPHT----QSCDKRDG--SCSCKAGFRGERCQA 684
TC GP C ++ P+ SC G SCSC GF G RC
Sbjct: 836 ---------TCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR 886
Query: 685 ---ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCS 741
EC GPG TC VA S C CP G+ G C Q+ P +CS
Sbjct: 887 DVDECLSNPCGPG-----TCTDHVA----SFTC--TCPPGYGGFHCEQDLP------DCS 929
Query: 742 -SSCSCGGAPCHGVTG-QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPET 799
SSC GG GV C C PG TG C+ + C + C H C
Sbjct: 930 PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP------C--LSRPCLHGGVCSAAH 981
Query: 800 GA--CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQ 857
C CL F G +CQ + W +R C N G C +C C PGW+G
Sbjct: 982 PGFRCTCLESFTGPQCQTL--VDWC-----SRQPCQNGGRCVQTGAYCLCPPGWSG---- 1030
Query: 858 RACDTGHWGPDCSHPCN-------------CSAGHGSC--DAISGLCLCEAGYVGPRCEQ 902
R CD S PC C AG G C + S C+C G G CEQ
Sbjct: 1031 RLCDIR------SLPCREAAAQIGVRLEQLCQAG-GQCVDEDSSHYCVCPEGRTGSHCEQ 1083
Query: 903 -------------------------QCPQGHFGPGCE---QRC---QCQHGAACDHVSG- 930
+C G+ G CE C CQHG +C +
Sbjct: 1084 EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVAR 1143
Query: 931 -ACTCPAGWRGTFCE--------------------------------HACPAGFFGLDCR 957
C+CP G G CE CP G+ GL C
Sbjct: 1144 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
Query: 958 SACNCTAGAACDAVNG-----------SCLCPAGRRGPRCAETCPAHTYGHNCSQACACF 1006
+ N AC A + CLC AG GPRC T C ++ C
Sbjct: 1204 ADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRC------QTVLSPC-ESQPCQ 1256
Query: 1007 NGASCDPVHG-------QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCD--PV 1057
+G C P G CHCA + GP C + +CR C G C P
Sbjct: 1257 HGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERV------ARSCR-ELQCPVGVPCQQTPR 1309
Query: 1058 SGHCACPEGWAGLACEK--ECLPRDVRAGCRHSGGCLNGGLCDPHT----GRCLCPAGWT 1111
CACP G +G +C P A C + CL+GG C P RC C GWT
Sbjct: 1310 GPRCACPPGLSGPSCRSFPGSPPGASNASCA-AAPCLHGGSCRPAPLAPFFRCACAQGWT 1368
Query: 1112 GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDC 1171
G +C++P E RC P AAC G RC GC G G DC
Sbjct: 1369 GPRCEAPAAAPEVSE--EPRC---PRAACQAKRGDQRCDRECNSPGC------GWDGGDC 1417
Query: 1172 ------------AQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLC 1219
A C N C PA + +C Y C P E+ C
Sbjct: 1418 SLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACL--YDNFDCHAGGRERTCNPVYEKYC 1475
Query: 1220 G-CLNGGSCDAATGACRCPTGFLGTDCNLTCP 1250
G CD C G+ G DC P
Sbjct: 1476 ADHFADGRCDQGCNTEEC--GWDGLDCASEVP 1505
Score = 338 bits (866), Expect = 3e-92
Identities = 335/1182 (28%), Positives = 415/1182 (35%), Gaps = 329/1182 (27%)
Query: 557 PDTFGKNCSFSCSCQNGGTCDSVTG---ACRCPPGVSGTNC--EDGCPKG---------- 601
P C C NGG C + AC CPPG G C ED C G
Sbjct: 36 PGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQS 95
Query: 602 -YYGKHCRKKCNCAN--RGRCHRLYGACLCDPGLYGRFCHL--------TCPPWAFGPGC 650
R C C RG L CL P +G C + +CPP G C
Sbjct: 96 SVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSC 155
Query: 651 S---EECQCVQP--HTQSCDKRDGS--CSCKAGFRGERCQAECELGYFGPGCWQACTCPV 703
+EC+ +P H +C GS C C AG+ G C+ P C TC
Sbjct: 156 RSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSP-CRNGGTCR- 213
Query: 704 GVACDSVSGECGKRCPAGFQGEDCG---QECPVGTFGVNCSSSCSCGGAPCHGV-TGQCR 759
++ +C C GF+G++C +CP C GG GV T C+
Sbjct: 214 --QSGDLTYDCA--CLPGFEGQNCEVNVDDCP--------GHRCLNGGTCVDGVNTYNCQ 261
Query: 760 CPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETG--ACLCLPGFVGSRCQD-- 815
CPP TG+ C D E CQ AC + C G +C+C+ G+ G C
Sbjct: 262 CPPEWTGQFCTEDVDE------CQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI 315
Query: 816 -----------------------VCPAGWYGPSCQTRCSCANDGHCH--------PATGH 844
CP G G C +C ++ CH P G
Sbjct: 316 DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN-PCHEDAICDTNPVNGR 374
Query: 845 --CSCAPGWTGFSCQRACDTGHWGPD-CSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCE 901
C+C PG+TG +C + D G + C H C GS LC C GY GPRCE
Sbjct: 375 AICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSF-----LCQCGRGYTGPRCE 429
Query: 902 QQCPQGHFGPGCEQRCQCQHGAACDHVSG--ACTCPAGWRGTFCEHACPAGFFGLDCRSA 959
+ GP C++ A C G C C AG+ GT+CE +C+S+
Sbjct: 430 TDVNECLSGP-------CRNQATCLDRIGQFTCICMAGFTGTYCEVDID------ECQSS 476
Query: 960 CNCTAGAACDAVNG-SCLCPAGRRG-------PRCAET-------CPAHTYGHNCSQACA 1004
G D VNG SC CP+G G CA T C G+ C +
Sbjct: 477 PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAE 535
Query: 1005 CFNGASC---------DPVHG----------QCHCAPGWMGPSCLQACPAGLYGDNCRHS 1045
F G C DP H C CAPG+ G C D CR S
Sbjct: 536 GFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQV------DECR-S 588
Query: 1046 CLCQNGGTC-DPVSGH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR 1103
C++GG C D V + C CP G G+ CE V S C G+C R
Sbjct: 589 QPCRHGGKCLDLVDKYLCRCPSGTTGVNCE-------VNIDDCASNPC-TFGVCRDGINR 640
Query: 1104 --CLCPAGWTGDKC--------QSPCLRGWFGEACAQ-----RCSCPPGA---------- 1138
C+C G+TG C SPC G +C RC CPPG+
Sbjct: 641 YDCVCQPGFTGPLCNVEINECASSPCGE---GGSCVDGENGFRCLCPPGSLPPLCLPPSH 697
Query: 1139 ----------ACHHVTGA--CRCPPGFTGSGCEQA------------------------- 1161
C+ G C C PG++G C Q+
Sbjct: 698 PCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFH 757
Query: 1162 --CPPGSFGEDCAQMCQCPGENPA-----CHPATG---TCSCAAGYHGPSCQQ------- 1204
CPPG G C + C NP C A G CSC G+ GP CQQ
Sbjct: 758 CTCPPGVQGRQCELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAG 816
Query: 1205 -------------------RCPPGRYGPGCEQLCG------CLNGGSCDAATG--ACRCP 1237
C G GP C+Q CLNGGSC G +C C
Sbjct: 817 PAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCL 876
Query: 1238 TGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG-TCLCPPGRAGVRCERGCPQNR 1296
GF G C + P CG G D V TC CPPG G CE+ P
Sbjct: 877 PGFAGPRCARDVDECLSNP-------CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPD-- 927
Query: 1297 FGVGCEHTCSCRNGGLC--HASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS 1354
C + SC NGG C ++ SC C G+TG HC+ P C L C +
Sbjct: 928 ----CSPS-SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP------C-LSRPCLHGG 975
Query: 1355 TCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLC-W-----CQHGAPCDPISGRCLC 1408
C A RC C F G CQ L W CQ+G C CLC
Sbjct: 976 VCSAAHPGFRC-----------TCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLC 1024
Query: 1409 PAGFHGHFCERGCEP-----GSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLD 1463
P G+ G C+ P G Q C G + + C+CP GR+G+ C
Sbjct: 1025 PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHC--- 1081
Query: 1464 CRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCRE 1505
+ P C GG C C+ GY G C +
Sbjct: 1082 --EQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED 1121
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 398 bits (1023), Expect = e-110
Identities = 411/1445 (28%), Positives = 541/1445 (37%), Gaps = 352/1445 (24%)
Query: 128 CSASLCFHGGRCVPGSAQ-PCHCPPGFQGPRCQYDVDECRTHNGGCQH--RCVNTPGSYL 184
C + C +G C + Q C C GF G +C+ DV+EC G CQH C+N PGSY
Sbjct: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP-GHCQHGGTCLNLPGSYQ 206
Query: 185 CECKPGFR-LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 243
C+C GF + DS S + G C+ Q C C PGF+ G C
Sbjct: 207 CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCR----QTGDFTFECNCLPGFE----GSTCE 258
Query: 244 RR-SPCANRNGSCMHRCQ----VVRGLARCECHVGYQLAADGKAC-EDVDECAAGLAQCA 297
R C N HRCQ V G+ C Q G+ C EDVDEC C
Sbjct: 259 RNIDDCPN------HRCQNGGVCVDGVNTYNCRCPPQWT--GQFCTEDVDECLLQPNACQ 310
Query: 298 HG--CLNTQGSFKCVCHAGYELGAD---------------GRQCYRIEMEIVNSCEANNG 340
+G C N G + CVC G+ G D G C C
Sbjct: 311 NGGTCANRNGGYGCVCVNGWS-GDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA 369
Query: 341 G--------CSHGCSHTSA----GPL-----CTCPRGYE-LDTDQRTCIDVDDCA--DSP 380
G C H A PL CTCP+GY+ D + DVD+CA +S
Sbjct: 370 GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTE----DVDECAMANSN 425
Query: 381 CCQQV--CTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGSFQCS 437
C+ C N G + C C GY G CE D++EC S + C + G F C
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYA----GPRCEMDINECHSDPCQNDATCLDKIGGFTCL 481
Query: 438 CEAGYR-LHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEE 496
C G++ +H + P V+ +G+ + + Q P F D ++
Sbjct: 482 CMPGFKGVHCELEINECQSNPCVN-NGQC-----VDKVNRFQCLCPPGFTGPVCQIDIDD 535
Query: 497 AELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCD--------CPEGWTG 548
C+D G++C C G C +D CD C +G
Sbjct: 536 C---SSTPCLNGAKCIDHPNGYECQ--CATGFTGVLCEENIDNCDPDPCHHGQCQDGIDS 590
Query: 549 LICNETCPPDTFGKNCS------FSCSCQNGGTC-DSVTG-ACRCPPGVSGTNCE---DG 597
C C P G CS +S C N G C D V G C C PG SG NCE D
Sbjct: 591 YTC--ICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDD 648
Query: 598 CPKGYYGKHCRKKCNCANRGRCHRLYG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQ 655
C N G C +C+C PG G+ C++ A P C +
Sbjct: 649 CAS-----------NPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNP-CRKGAT 696
Query: 656 CVQ------------PHTQSCDKRDGSC--------SCKAGFRGERCQAECELGYFGPGC 695
C+ PH SC + C +C G G +C C+ G+ G C
Sbjct: 697 CINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCL--CDAGWVGINC 754
Query: 696 ------WQACTCPVGVACDSVSGECGKRCPAGFQGEDCG---QECPVGTFGVNCSSSCSC 746
+ C G CD++ C GF+G +C EC S+ C
Sbjct: 755 EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDEC--------ASNPCLN 806
Query: 747 GGAPCHGVTG-QCRCPPGRTGEDCE---ADCPEGRWGLGCQEICPACQHAARCDP----E 798
G ++G C C TG++C+ A C C++AA C E
Sbjct: 807 QGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN-----------PCENAAVCKESPNFE 855
Query: 799 TGACLCLPGFVGSRCQ-DVCPAGWYGPSCQTRCSCANDGHCHPATGH--CSCAPGWTGFS 855
+ CLC PG+ G RC D+ C ++ C N G CH G C C PG++G
Sbjct: 856 SYTCLCAPGWQGQRCTIDI-------DECISK-PCMNHGLCHNTQGSYMCECPPGFSGMD 907
Query: 856 CQRACDTGHWGPDC-SHPCNCSAGHGSC-DAISGL-CLCEAGYVGPRCEQQCPQGHFGPG 912
C+ D DC ++PC GSC D ++ CLC G+ G +C+ + P
Sbjct: 908 CEEDID------DCLANPCQ---NGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP- 957
Query: 913 CEQRCQCQHGAAC-DHV-SGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDA 970
C++G C D+V S C C AG+ G CE+ +C + G D
Sbjct: 958 ------CKNGGTCSDYVNSYTCKCQAGFDGVHCENNIN------ECTESSCFNGGTCVDG 1005
Query: 971 VNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC 1029
+N SCLCP G G C + CS + C N +C G C
Sbjct: 1006 INSFSCLCPVGFTGSFCLHEI------NECS-SHPCLNEGTCVDGLGTYRC--------- 1049
Query: 1030 LQACPAGLYGDNCR---HSCL---CQNGGTC--DPVSGHCACPEGWAGLACEKECLPRDV 1081
+CP G G NC+ + C C+N GTC C CP GWAG C+ + D+
Sbjct: 1050 --SCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 1082 RAG---------CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRC 1132
A C+HSG C+N G +T C CP G+TG C+ + CA
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAG----NTHYCQCPLGYTGSYCEEQL------DECASN- 1156
Query: 1133 SCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCA-QMCQCPGENPACHPATG 1189
C GA C G C C PG+ G CE ++C Q CQ G C
Sbjct: 1157 PCQHGATCSDFIGGYRCECVPGYQGVNCEYEV------DECQNQPCQNGG---TCIDLVN 1207
Query: 1190 --TCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG--ACRCPTGFLGTDC 1245
CSC G G C++ GP CLNGG C G +CRC GF G C
Sbjct: 1208 HFKCSCPPGTRGLLCEENIDDCARGP------HCLNGGQCMDRIGGYSCRCLPGFAGERC 1261
Query: 1246 ----------------NLTCPQ--------------GRFGPNCTHVC---GCGQGAACD- 1271
+L C Q GR VC C G C
Sbjct: 1262 EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAV 1321
Query: 1272 ----PVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLC-HASNG-SCSCGLG 1325
P C CPPG +G RC+ C Q CR G C H ++G C C
Sbjct: 1322 ASNMPDGFICRCPPGFSGARCQSSCGQ----------VKCRKGEQCVHTASGPRCFCP-- 1369
Query: 1326 WTGRHCELAC--PPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE-HPCPPGF 1382
+ R CE C P ++G +CH + +P +C+C P F G CE + PP
Sbjct: 1370 -SPRDCESGCASSPCQHGGSCHPQ--------RQPPYYSCQCAPPFSGSRCELYTAPPST 1420
Query: 1383 HGAGC 1387
A C
Sbjct: 1421 PPATC 1425
Score = 377 bits (967), Expect = e-104
Identities = 384/1384 (27%), Positives = 511/1384 (36%), Gaps = 302/1384 (21%)
Query: 127 ECSASLCFHGGRCVPG-SAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH--RCVNTPGSY 183
+C C +GG CV G + C CPP + G C DVDEC CQ+ C N G Y
Sbjct: 263 DCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGY 322
Query: 184 LCECKPG--------------FRLHTDSRTCL---AINSCAL--GNGGCQHHCVQLTIT- 223
C C G F T TC+ A SC G G H I+
Sbjct: 323 GCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISN 382
Query: 224 ---------------RHRCQCRPGFQLQEDGRHCVRR-SPCANRNGS-CMH--RCQVVRG 264
++ C C G++ G C CA N + C H +C G
Sbjct: 383 PCHKGALCDTNPLNGQYICTCPQGYK----GADCTEDVDECAMANSNPCEHAGKCVNTDG 438
Query: 265 LARCECHVGYQLAADGKACE-DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQ 323
CEC GY G CE D++EC + Q CL+ G F C+C G++ G
Sbjct: 439 AFHCECLKGYA----GPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK----GVH 490
Query: 324 CYRIEMEIVNSCEA----NNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS 379
C E+EI N C++ NNG C + C CP G+ T ID+DDC+ +
Sbjct: 491 C---ELEI-NECQSNPCVNNGQCVDKVNRFQ----CLCPPGF---TGPVCQIDIDDCSST 539
Query: 380 PCCQQV-CTNNPGGYECGCYAGYRLSADGCGCED-VDECASSRGGCEH-HCTNLAGSFQC 436
PC C ++P GYEC C G+ G CE+ +D C C H C + S+ C
Sbjct: 540 PCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDNC--DPDPCHHGQCQDGIDSYTC 593
Query: 437 SCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEE 496
C GY A+ D++ + + + D
Sbjct: 594 ICNPGYM------------------------------GAICSDQIDECYSSPCLN-DGRC 622
Query: 497 AELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNG----GTCLLGLD--GCDCPEGWTGLI 550
+L + C + G +C + DDC + G C+ G++ C C G+TG
Sbjct: 623 IDLVNGYQCN----CQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQR 678
Query: 551 CN---ETCP--PDTFGKNC-----SFSCSCQNG---GTCDSVTGACRCPPGVSGTNCEDG 597
CN + C P G C F C C G +C S C P + G NC G
Sbjct: 679 CNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGG 737
Query: 598 -------CPKGYYGKHCRKKCN------CANRGRCHRLYGA--CLCDPGLYGRFCHLTCP 642
C G+ G +C N C N G C L C C G G C +
Sbjct: 738 LSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNID 797
Query: 643 PWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCP 702
A P C+ T D +C C + G+ CQ P C A C
Sbjct: 798 ECASNP-------CLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNP-CENAAVCK 849
Query: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRC 760
+S + C C G+QG+ C + C S CH G C C
Sbjct: 850 ESPNFESYT--C--LCAPGWQGQRCTIDID------ECISKPCMNHGLCHNTQGSYMCEC 899
Query: 761 PPGRTGEDCEADCPEGRWGLGCQEICPACQHAARC--DPETGACLCLPGFVGSRCQ---- 814
PPG +G DCE D + C + CQ+ C T +CLCLPGF G +CQ
Sbjct: 900 PPGFSGMDCEEDIDD------C--LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMN 951
Query: 815 ----DVCPAGW----YGPSCQTRCSCANDG-HCHPATGHC---------SCAPGWTGFSC 856
+ C G Y S +C DG HC C +C G FSC
Sbjct: 952 ECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSC 1011
Query: 857 QRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE-- 914
C G G C H N + H + G C+ G RC CP G+ G C+
Sbjct: 1012 --LCPVGFTGSFCLHEINECSSHPCLN--EGTCVDGLGTY--RC--SCPLGYTGKNCQTL 1063
Query: 915 ----QRCQCQHGAAC--DHVSGACTCPAGWRGTFCE---HAC--PAGFFGLDCRSACNCT 963
R C++ C C CP+GW G +C+ +C A G+ C
Sbjct: 1064 VNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQ-H 1122
Query: 964 AGAACDAVNGS-CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHC 1020
+G +A N C CP G G C E C+ + C +GA+C G +C C
Sbjct: 1123 SGVCINAGNTHYCQCPLGYTGSYCEEQL------DECA-SNPCQHGATCSDFIGGYRCEC 1175
Query: 1021 APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGH--CACPEGWAGLACEKECLP 1078
PG+ G +C D C++ CQNGGTC + H C+CP G GL CE+
Sbjct: 1176 VPGYQGVNCEYEV------DECQNQ-PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENI-- 1226
Query: 1079 RDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPP 1136
C CLNGG C G C C G+ G++C+ G E + CS
Sbjct: 1227 ----DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE-----GDINECLSNPCSSEG 1277
Query: 1137 GAACHHVTG--ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCA 1194
C +T C C FTG CE +F + C QM G GTC+ A
Sbjct: 1278 SLDCIQLTNDYLCVCRSAFTGRHCE------TFVDVCPQMPCLNG---------GTCAVA 1322
Query: 1195 AGY-HGPSCQQRCPPGRYGPGCEQLCG---CLNGGSC--DAATGACRCPTGFLGTDCNLT 1248
+ G C RCPPG G C+ CG C G C A+ C CP+ DC
Sbjct: 1323 SNMPDGFIC--RCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPS---PRDCESG 1377
Query: 1249 CPQGRFGPNCTHVCGCGQGAACDPVTG----TCLCPPGRAGVRCE-RGCPQNRFGVGC-- 1301
C C G +C P +C C P +G RCE P + C
Sbjct: 1378 CASS----------PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLS 1427
Query: 1302 EHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATG 1361
++ G+C + S +C W G C L + L C + N+ C+
Sbjct: 1428 QYCADKARDGVCDEACNSHAC--QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCN 1485
Query: 1362 TCRC 1365
T C
Sbjct: 1486 TVEC 1489
Score = 352 bits (902), Expect = 2e-96
Identities = 385/1493 (25%), Positives = 516/1493 (34%), Gaps = 376/1493 (25%)
Query: 225 HRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE 284
H QCR G++ PC N G C+ G C+C G+ G+ C+
Sbjct: 24 HALQCRDGYE------------PCVNE-GMCV---TYHNGTGYCKCPEGFL----GEYCQ 63
Query: 285 DVDECAAGLAQCAHGCLNTQ--GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC 342
D C Q C+ G C C +G+ G D C
Sbjct: 64 HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFT-GED---------------------C 101
Query: 343 SHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYR 402
+ SH C C + C + + YEC C G+
Sbjct: 102 QYSTSHP--------------------CFVSRPCLNGGTCHMLSRDT---YECTCQVGFT 138
Query: 403 LSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEP----- 457
G C+ D C S CT +A F C C G+ + + + P
Sbjct: 139 ----GKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQH 194
Query: 458 ---MVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDD 514
++L G P D L+ R T + CL
Sbjct: 195 GGTCLNLPGSYQCQCPQGFTGQYCD---SLYVPCAPSPCVNGGTCRQTGDFTFECNCLPG 251
Query: 515 SFGHDCSLTCDD-----CRNGGTCLLGLD--GCDCPEGWTGLICNETCPPDTFGKNCSFS 567
G C DD C+NGG C+ G++ C CP WTG C E N
Sbjct: 252 FEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN---- 307
Query: 568 CSCQNGGTCDSVTG--ACRCPPGVSGTNCEDG-------------------------CPK 600
+CQNGGTC + G C C G SG +C + CP+
Sbjct: 308 -ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPE 366
Query: 601 GYYGKHCRKKCNCANRGRCHRLYGACLCDPG-LYGRFCHLTCPPWAFGPGCSEEC-QCVQ 658
G G C C + CH+ LCD L G++ TCP G C+E+ +C
Sbjct: 367 GKAGLLCHLDDACIS-NPCHK---GALCDTNPLNGQYI-CTCPQGYKGADCTEDVDECAM 421
Query: 659 ------PHTQSCDKRDGS--CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSV 710
H C DG+ C C G+ G RC+ + + P C TC D +
Sbjct: 422 ANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDP-CQNDATC-----LDKI 475
Query: 711 SG-ECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPGRTGE 767
G C C GF+G C E C S+ C QC CPPG TG
Sbjct: 476 GGFTC--LCMPGFKGVHCELEIN------ECQSNPCVNNGQCVDKVNRFQCLCPPGFTGP 527
Query: 768 DCEAD-------------------------CPEGRWGLGCQEICPACQ----HAARCDP- 797
C+ D C G G+ C+E C H +C
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDG 587
Query: 798 -ETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPGWTGF 854
++ C+C PG++G+ C D + P C NDG C C+C PG +G
Sbjct: 588 IDSYTCICNPGYMGAICSDQIDECYSSP-------CLNDGRCIDLVNGYQCNCQPGTSGV 640
Query: 855 SCQRACDTGHWGPDC-SHPCNCSAGHGSC-DAISGL-CLCEAGYVGPRCEQQ-------- 903
+C+ D DC S+PC HG C D I+ C+C G+ G RC
Sbjct: 641 NCEINFD------DCASNPCI----HGICMDGINRYSCVCSPGFTGQRCNIDIDECASNP 690
Query: 904 -----------------CPQGHFGPGCEQRCQ------CQHGAACDHVSG-ACTCPAGWR 939
CP+G P C + C HG +SG C C AGW
Sbjct: 691 CRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWV 750
Query: 940 GTFCE-------------------------HACPAGFFGLDCRSACNCTAGAAC------ 968
G CE C GF G +C+ + A C
Sbjct: 751 GINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTC 810
Query: 969 -DAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMG 1026
D ++G +C C G C +T A + C A C + + C CAPGW G
Sbjct: 811 FDDISGYTCHCVLPYTGKNC-QTVLAPCSPNPCENAAVCKESPNFESY--TCLCAPGWQG 867
Query: 1027 PSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGH--CACPEGWAGLACEK---ECLPRDV 1081
C + D C S C N G C G C CP G++G+ CE+ +CL
Sbjct: 868 QRCT------IDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP- 919
Query: 1082 RAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACH 1141
C++ G C++G +T CLC G+TGDKCQ+ E ++ C G C
Sbjct: 920 ---CQNGGSCMDG----VNTFSCLCLPGFTGDKCQTD-----MNECLSE--PCKNGGTCS 965
Query: 1142 HVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHG 1199
+ C+C GF G CE +C + G + +C C G+ G
Sbjct: 966 DYVNSYTCKCQAGFDGVHCENNI------NECTESSCFNGGTCVDGINSFSCLCPVGFTG 1019
Query: 1200 PSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPN 1257
C P CLN G+C G C CP G+ G +C P
Sbjct: 1020 SFCLHEINECSSHP-------CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSP- 1071
Query: 1258 CTHVCGCGQGAACDPVTGTCLCPPGRAGVRCE-----RGCPQNRFGVGCEHTCS----CR 1308
C + C Q A CLCP G AG C+ +R GV EH C C
Sbjct: 1072 CKNKGTCVQKKA----ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCI 1127
Query: 1309 NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECS---CHNNSTCEPATG--TC 1363
N G H C C LG+TG +CE EC+ C + +TC G C
Sbjct: 1128 NAGNTH----YCQCPLGYTGSYCEEQLD----------ECASNPCQHGATCSDFIGGYRC 1173
Query: 1364 RCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISG--RCLCPAGFHGHFCERGC 1421
C PG+ G CE+ CQ CQ+G C + +C CP G G CE
Sbjct: 1174 ECVPGYQGVNCEYEVDE------CQNQP-CQNGGTCIDLVNHFKCSCPPGTRGLLCEENI 1226
Query: 1422 EPGSFGEGCHQRCDCDGGAPCDPVTGL-CLCPPGRSGATCNLDCRRGQFGPSCTLHCDCG 1480
+ + G C +GG D + G C C PG +G C D P C
Sbjct: 1227 DDCARGPHC-----LNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNP-----CSSE 1276
Query: 1481 GGADCDPVSGQ--CHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRP 1531
G DC ++ C C + G C + P+ P L G+ AS+ P
Sbjct: 1277 GSLDCIQLTNDYLCVCRSAFTGRHCETFVDV-CPQMPCLNGGTCAV--ASNMP 1326
Score = 341 bits (875), Expect = 3e-93
Identities = 372/1317 (28%), Positives = 470/1317 (35%), Gaps = 430/1317 (32%)
Query: 511 CLDDSFGHDCSLT---CD---DCRNGGTCLL--GLDGCDCPEGWTGLICNETCPPDTFGK 562
CL G C CD C++GGTCL G C CP+G+TG C+ P
Sbjct: 170 CLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVP----- 224
Query: 563 NCSFSCSCQNGGTCDSV---TGACRCPPGVSGTNCE---DGCPKGYYGKHCRKKCNCANR 616
C+ S C NGGTC T C C PG G+ CE D CP
Sbjct: 225 -CAPS-PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPN---------------- 266
Query: 617 GRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC-QCV-QPHT----QSCDKRDGS 670
HR +C G+ C CPP G C+E+ +C+ QP+ +C R+G
Sbjct: 267 ---HRCQNGGVCVDGVNTYNCR--CPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 671 --CSCKAGFRGERCQA---ECELGYFGPG--CWQ-----ACTCPVGVA------------ 706
C C G+ G+ C +C PG C +C CP G A
Sbjct: 322 YGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACIS 381
Query: 707 --------CDS--VSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG 756
CD+ ++G+ CP G++G DC ++ V + S+ C G C G
Sbjct: 382 NPCHKGALCDTNPLNGQYICTCPQGYKGADCTED--VDECAMANSNPCEHAGK-CVNTDG 438
Query: 757 --QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSR 812
C C G G CE D E C CQ+ A C + G CLC+PGF G
Sbjct: 439 AFHCECLKGYAGPRCEMDINE------CHS--DPCQNDATCLDKIGGFTCLCMPGFKGVH 490
Query: 813 C-------------------------QDVCPAGWYGPSCQTR---CS---CANDGHC--H 839
C Q +CP G+ GP CQ CS C N C H
Sbjct: 491 CELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDH 550
Query: 840 PATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSC-DAI-SGLCLCEAGYVG 897
P C CA G+TG C+ D + PD PC+ HG C D I S C+C GY+G
Sbjct: 551 PNGYECQCATGFTGVLCEENID--NCDPD---PCH----HGQCQDGIDSYTCICNPGYMG 601
Query: 898 PRCEQQCPQGHFGPGCEQRCQCQHGAAC-DHVSG-ACTCPAGWRGTFCEHACPAGFFGLD 955
C Q + + P C + C D V+G C C G G CE D
Sbjct: 602 AICSDQIDECYSSP-------CLNDGRCIDLVNGYQCNCQPGTSGVNCE-------INFD 647
Query: 956 CRSACNCTAGAACDAVNG-SCLCPAGRRGPRC---AETCPAHTYGHNCSQACACFNGAS- 1010
++ C G D +N SC+C G G RC + C ++ C + C NG +
Sbjct: 648 DCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNP----CRKGATCINGVNG 703
Query: 1011 ----CD--PVHGQCH---------------CAPGWMGPSCLQACPAGLYGDNC---RHSC 1046
C P H C+ C G G CL C AG G NC ++ C
Sbjct: 704 FRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCL--CDAGWVGINCEVDKNEC 761
Query: 1047 L---CQNGGTCDP-VSGH-CACPEGWAGLACE---KECLPRDVRAGCRHSGGCLNGGLC- 1097
L CQNGGTCD V+G+ C C +G+ G C+ EC S CLN G C
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECA----------SNPCLNQGTCF 811
Query: 1098 DPHTG-RCLCPAGWTGDKCQ-------------------SP--------CLRGWFGEACA 1129
D +G C C +TG CQ SP C GW G+ C
Sbjct: 812 DDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCT 871
Query: 1130 ---QRC---SCPPGAACHHVTGA--CRCPPGFTGSGCEQ--------------------- 1160
C C CH+ G+ C CPPGF+G CE+
Sbjct: 872 IDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVN 931
Query: 1161 ----ACPPGSFGEDC-AQMCQCPGENPACHPATG-------TCSCAAGYHGPSCQQRCPP 1208
C PG G+ C M +C E P + T TC C AG+ G C+
Sbjct: 932 TFSCLCLPGFTGDKCQTDMNECLSE-PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINE 990
Query: 1209 GRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDC--------------------- 1245
C + C NGG+C + C CP GF G+ C
Sbjct: 991 ------CTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDG 1043
Query: 1246 ----NLTCPQGRFGPNC---THVCG---CGQGAAC--DPVTGTCLCPPGRAGVRCER--- 1290
+CP G G NC ++C C C CLCP G AG C+
Sbjct: 1044 LGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103
Query: 1291 --GCPQNRFGVGCEHTCS----CRNGGLCHASNGSCSCGLGWTGRHCE------------ 1332
+R GV EH C C N G H C C LG+TG +CE
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHY----CQCPLGYTGSYCEEQLDECASNPCQ 1159
Query: 1333 -------------LACPPGRYGAACHLECS------CHNNSTCEPATG--TCRCGPGFYG 1371
C PG G C E C N TC C C PG G
Sbjct: 1160 HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRG 1219
Query: 1372 QACEHP--------------------------CPPGFHGAGCQG--------LCWCQHGA 1397
CE C PGF G C+G C +
Sbjct: 1220 LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSL 1279
Query: 1398 PCDPISGR--CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGG----APCDPVTGLCLC 1451
C ++ C+C + F G CE +F + C Q +GG A P +C C
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCE------TFVDVCPQMPCLNGGTCAVASNMPDGFICRC 1333
Query: 1452 PPGRSGATC-----NLDCRRGQ------FGPSCTLHC--DCGGGADCDPV--SGQCH 1493
PPG SGA C + CR+G+ GP C DC G P G CH
Sbjct: 1334 PPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCH 1390
Score = 313 bits (801), Expect = 1e-84
Identities = 343/1271 (26%), Positives = 438/1271 (34%), Gaps = 383/1271 (30%)
Query: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDG---CDCPEGWTGLICNETCPPDTFGKNCSFS 567
C + C + C N G C+ +G C CPEG+ G C P + KN
Sbjct: 19 CAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCE---KN---- 71
Query: 568 CSCQNGGTCDSVT----GACRCPPGVSGTNCEDGCPKGYYGKH-CRKKCNCANRGRCHRL 622
CQNGGTC + CRC G +G +C+ Y H C C N G CH L
Sbjct: 72 -RCQNGGTCVAQAMLGKATCRCASGFTGEDCQ------YSTSHPCFVSRPCLNGGTCHML 124
Query: 623 YG---ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRG 679
C C G G+ C T C C T + SC C GF G
Sbjct: 125 SRDTYECTCQVGFTGKECQWT-------DACLSH-PCANGSTCTTVANQFSCKCLTGFTG 176
Query: 680 ERCQA---ECEL-GYFG--------PGCWQACTCPVGVA---CDSVSGECGK-------- 716
++C+ EC++ G+ PG +Q C CP G CDS+ C
Sbjct: 177 QKCETDVNECDIPGHCQHGGTCLNLPGSYQ-CQCPQGFTGQYCDSLYVPCAPSPCVNGGT 235
Query: 717 -----------RCPAGFQGEDCGQ---ECPVGTFGVNCSSSCSCGGAPCHGV-TGQCRCP 761
C GF+G C + +CP + C GG GV T CRCP
Sbjct: 236 CRQTGDFTFECNCLPGFEGSTCERNIDDCP--------NHRCQNGGVCVDGVNTYNCRCP 287
Query: 762 PGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETG--ACLCLPGFVGSRCQD---- 815
P TG+ C D E C ACQ+ C G C+C+ G+ G C +
Sbjct: 288 PQWTGQFCTEDVDE------CLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341
Query: 816 ---------------------VCPAGWYGPSCQTRCSCANDGHCH--------PATGH-- 844
+CP G G C +C ++ CH P G
Sbjct: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISN-PCHKGALCDTNPLNGQYI 400
Query: 845 CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL--CLCEAGYVGPRCEQ 902
C+C G+ G C D S+PC + G C G C C GY GPRCE
Sbjct: 401 CTCPQGYKGADCTE--DVDECAMANSNPCEHA---GKCVNTDGAFHCECLKGYAGPRCEM 455
Query: 903 QCPQGHFGPGCEQRCQCQHGAAC-DHVSG-ACTCPAGWRGTFCEHACPAGFFGLDCRSAC 960
+ H P CQ+ A C D + G C C G++G CE +C+S
Sbjct: 456 DINECHSDP-------CQNDATCLDKIGGFTCLCMPGFKGVHCELEIN------ECQSNP 502
Query: 961 NCTAGAACDAVNG-SCLCPAGRRGPRC--------------AETCPAHTYGHNCSQACAC 1005
G D VN CLCP G GP C C H G+ C Q
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYEC-QCATG 561
Query: 1006 FNGA-------SCDP---VHGQCH---------CAPGWMGPSCLQACPAGLYGDNCRHSC 1046
F G +CDP HGQC C PG+MG C D C +S
Sbjct: 562 FTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQI------DEC-YSS 614
Query: 1047 LCQNGGTC-DPVSGH-CACPEGWAGLACE---KECLPRDVRAGCRHSGGCLNGGLCDPHT 1101
C N G C D V+G+ C C G +G+ CE +C C H G C++G +
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP----CIH-GICMDG----INR 665
Query: 1102 GRCLCPAGWTGDKC--------QSPCLRG--WFGEACAQRCSCPPG---AACH------- 1141
C+C G+TG +C +PC +G RC CP G +C+
Sbjct: 666 YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECL 725
Query: 1142 -------HVTGA-----CRCPPGFTGSGCEQ-------------------------ACPP 1164
+ TG C C G+ G CE C
Sbjct: 726 SNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKK 785
Query: 1165 GSFGEDCAQMCQCPGENPACHPAT-------GTCSCAAGYHGPSCQQ------------- 1204
G G +C NP + T TC C Y G +CQ
Sbjct: 786 GFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENA 845
Query: 1205 --------------RCPPGRYGPGCE---QLC---GCLNGGSCDAATGA--CRCPTGFLG 1242
C PG G C C C+N G C G+ C CP GF G
Sbjct: 846 AVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSG 905
Query: 1243 TDCNLTCPQGRFGPNCTHVCGCGQGAAC-DPV-TGTCLCPPGRAGVRCERGCPQNRFGVG 1300
DC P C G +C D V T +CLC PG G +C+ +
Sbjct: 906 MDCEEDIDDCLANP-------CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE------ 952
Query: 1301 CEHTCSCRNGGLC--HASNGSCSCGLGWTGRHCE-------------------------L 1333
C C+NGG C + ++ +C C G+ G HCE
Sbjct: 953 CLSE-PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSC 1011
Query: 1334 ACPPGRYGAAC---HLECSCH---NNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGC 1387
CP G G+ C ECS H N TC GT RC CP G+ G C
Sbjct: 1012 LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCS-----------CPLGYTGKNC 1060
Query: 1388 QGLCWCQHGAPC--------DPISGRCLCPAGFHGHFCE---RGCEPGSFGEGCHQRCDC 1436
Q L +PC +CLCP+G+ G +C+ C+ + G C
Sbjct: 1061 QTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLC 1120
Query: 1437 DGGAPCDPV--TGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSG--QC 1492
C T C CP G +G+ C P C GA C G +C
Sbjct: 1121 QHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP-------CQHGATCSDFIGGYRC 1173
Query: 1493 HCVDGYMGPTC 1503
CV GY G C
Sbjct: 1174 ECVPGYQGVNC 1184
Score = 295 bits (756), Expect = 2e-79
Identities = 313/1174 (26%), Positives = 432/1174 (36%), Gaps = 242/1174 (20%)
Query: 127 ECSASLCFHGGRCVPGSAQ-PCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLC 185
EC ++ C + G+CV + C CPPGF GP CQ D+D+C + +C++ P Y C
Sbjct: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYEC 556
Query: 186 ECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQ--LQEDGRHCV 243
+C GF T I++C C H Q I + C C PG+ + D
Sbjct: 557 QCATGF---TGVLCEENIDNC--DPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDEC 611
Query: 244 RRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGLAQCAHG-CL 301
SPC N +G C+ +V G +C C G G CE + D+CA+ C HG C+
Sbjct: 612 YSSPCLN-DGRCI---DLVNGY-QCNCQPG----TSGVNCEINFDDCASN--PCIHGICM 660
Query: 302 NTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGY 361
+ + CVC G+ G++C I+ ++ C +N C + G C CP G
Sbjct: 661 DGINRYSCVCSPGFT----GQRC-NID---IDECASNPCRKGATCINGVNGFRCICPEG- 711
Query: 362 ELDTDQRTCID-VDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASS 419
+C V++C +PC CT GY+C C AG+ G CE D +EC S+
Sbjct: 712 ---PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNECLSN 764
Query: 420 RGGCEHHCTNLAGSFQCSCEAGYR-----LHEDRRGCSPLEEPMVDLDGELPFV--RPLP 472
C NL ++C+C+ G++ ++ D +P D + LP
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 473 HI-----AVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDD- 526
+ VL P ++ V + E + +C G C++ D+
Sbjct: 825 YTGKNCQTVLAPCSPNPCENAAVCKESPNFE-------SYTCLCAPGWQGQRCTIDIDEC 877
Query: 527 ----CRNGGTC--LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC-DSV 579
C N G C G C+CP G++G+ C E +C + CQNGG+C D V
Sbjct: 878 ISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI------DDC-LANPCQNGGSCMDGV 930
Query: 580 -TGACRCPPGVSGTNCEDG-------------------------CPKGYYGKHCRKKCN- 612
T +C C PG +G C+ C G+ G HC N
Sbjct: 931 NTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINE 990
Query: 613 -----CANRGRCHRLYG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCD 665
C N G C +CLC G G FC + P C E CV
Sbjct: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHP-CLNEGTCV-------- 1041
Query: 666 KRDG----SCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAG 721
DG CSC G+ G+ CQ L P C C E CP+G
Sbjct: 1042 --DGLGTYRCSCPLGYTGKNCQTLVNLCSRSP-------CKNKGTCVQKKAESQCLCPSG 1092
Query: 722 FQGEDC---GQECPVGTF--GVNCSSSCSCGGAPCH-GVTGQCRCPPGRTGEDCEADCPE 775
+ G C C + GV C G + G T C+CP G TG CE E
Sbjct: 1093 WAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Query: 776 GRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCA 833
C CQH A C G C C+PG+ G C+ + CQ + C
Sbjct: 1153 ------CAS--NPCQHGATCSDFIGGYRCECVPGYQGVNCE------YEVDECQNQ-PCQ 1197
Query: 834 NDGHCHPATGH--CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL-CL 890
N G C H CSC PG G C+ D DC+ +C G D I G C
Sbjct: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEENID------DCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 891 CEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSG--ACTCPAGWRGTFCE---H 945
C G+ G RCE G C + C ++ C C + + G CE
Sbjct: 1252 CLPGFAGERCE-----GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVD 1306
Query: 946 ACPAGFFGLDCRSACNCTAGAACDAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACA 1004
CP + C + C A + +G C CP G G RC +C
Sbjct: 1307 VCPQ----MPCLNGGTC--AVASNMPDGFICRCPPGFSGARCQSSC----------GQVK 1350
Query: 1005 CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSG----H 1060
C G C H A GP C CP+ ++ S CQ+GG+C P
Sbjct: 1351 CRKGEQC------VHTA---SGPRCF--CPSPRDCESGCASSPCQHGGSCHPQRQPPYYS 1399
Query: 1061 CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL 1120
C C ++G CE P P T C + + DK +
Sbjct: 1400 CQCAPPFSGSRCELYTAP--------------------PSTPPATCLSQYCADKARD--- 1436
Query: 1121 RGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSF-GEDCAQMC---Q 1176
G EAC AC G C + C P + C ++C +
Sbjct: 1437 -GVCDEACNSH-------ACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVE 1488
Query: 1177 CPGENPACHPATGTCS----CAAGYHGPSCQQRC 1206
C +N C + TC CA + C Q C
Sbjct: 1489 CLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGC 1522
Score = 217 bits (552), Expect = 8e-56
Identities = 229/892 (25%), Positives = 332/892 (37%), Gaps = 160/892 (17%)
Query: 110 CCRGWMQ---QPDEEGCLSAECSASLCFHGGRCVP-GSAQPCHCPPGFQGPRCQYDVDEC 165
C GW+ + D+ CLS C +GG C + C C GF+G CQ ++DEC
Sbjct: 745 CDAGWVGINCEVDKNECLSNPCQ-----NGGTCDNLVNGYRCTCKKGFKGYNCQVNIDEC 799
Query: 166 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCV---QLTI 222
++ Q C + Y C C L + C + + N C++ V
Sbjct: 800 ASNPCLNQGTCFDDISGYTCHCV----LPYTGKNCQTVLAPCSPN-PCENAAVCKESPNF 854
Query: 223 TRHRCQCRPGFQLQE---DGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 279
+ C C PG+Q Q D C+ + PC N C +G CEC G+
Sbjct: 855 ESYTCLCAPGWQGQRCTIDIDECISK-PCMNHG-----LCHNTQGSYMCECPPGF----S 904
Query: 280 GKAC-EDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAN 338
G C ED+D+C A Q C++ +F C+C G+ G +C + +M S
Sbjct: 905 GMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF----TGDKC-QTDMNECLSEPCK 959
Query: 339 NGGCSHGCSHTSAGPLCTCPRGYELDTDQRTC-IDVDDCADSPCCQ-QVCTNNPGGYECG 396
NGG CS C C G+ D C ++++C +S C C + + C
Sbjct: 960 NGGT---CSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFNGGTCVDGINSFSCL 1012
Query: 397 CYAGYRLSADGCGC-EDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLE 455
C G+ G C +++EC+S E C + G+++CSC GY + C
Sbjct: 1013 CPVGF----TGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY----TGKNC---- 1060
Query: 456 EPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDS 515
+ +V+L P + + E L GA + + + + + V ++
Sbjct: 1061 QTLVNLCSRSP-CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHL 1119
Query: 516 FGHDCSLTCDDCRNGGTCLL--GLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG 573
C++ G C+ C CP G+TG C E C+ S CQ+G
Sbjct: 1120 -----------CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL------DECA-SNPCQHG 1161
Query: 574 GTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL--YGACLCD 629
TC G C C PG G NCE Y C+ + C N G C L + C C
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCE------YEVDECQNQ-PCQNGGTCIDLVNHFKCSCP 1214
Query: 630 PGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDG-SCSCKAGFRGERCQAECEL 688
PG G C A GP C QC+ D+ G SC C GF GERC+ +
Sbjct: 1215 PGTRGLLCEENIDDCARGPHCLNGGQCM-------DRIGGYSCRCLPGFAGERCEGDINE 1267
Query: 689 GYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGG 748
P C+ + C ++ + C + F G C TF C G
Sbjct: 1268 CLSNP-----CSSEGSLDCIQLTNDYLCVCRSAFTGRHC------ETFVDVCPQMPCLNG 1316
Query: 749 APCHGVTGQ-----CRCPPGRTGEDCEADCPEGRWGLGCQEI---------CPA------ 788
C + CRCPPG +G C++ C + + G Q + CP+
Sbjct: 1317 GTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCES 1376
Query: 789 ------CQHAARCDPETG----ACLCLPGFVGSRCQ------DVCPAGWYGPSCQTRCSC 832
CQH C P+ +C C P F GSRC+ PA C +
Sbjct: 1377 GCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK--- 1433
Query: 833 ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNC-SAGHGSCDAISGLCLC 891
A DG C A +C W G C + W +CS P C + CD + C
Sbjct: 1434 ARDGVCDEACNSHACQ--WDGGDCSLTME-NPWA-NCSSPLPCWDYINNQCDELCNTVEC 1489
Query: 892 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFC 943
+ C+ + C + H CD + C GW G C
Sbjct: 1490 L--FDNFECQGNSKTCKYDKYCADHFKDNH---CDQGCNSEEC--GWDGLDC 1534
Score = 103 bits (257), Expect = 1e-21
Identities = 124/501 (24%), Positives = 186/501 (37%), Gaps = 109/501 (21%)
Query: 103 EARTVLRCCRGWMQQPDEEGCLSAECSAS--------LCFHGGRCV-PGSAQPCHCPPGF 153
+A + C GW + +S + +AS LC H G C+ G+ C CP G+
Sbjct: 1082 KAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141
Query: 154 QGPRCQYDVDECRTHNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTC-LAINSCALGN 210
G C+ +DEC ++ CQH C + G Y CEC PG++ C ++ C N
Sbjct: 1142 TGSYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQ----GVNCEYEVDECQ--N 1193
Query: 211 GGCQHHCVQLTITRH-RCQCRPGFQ---LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLA 266
CQ+ + + H +C C PG + +E+ C R C N G CM R G
Sbjct: 1194 QPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLN-GGQCMDRI----GGY 1248
Query: 267 RCECHVGYQLAADGKACE-DVDECAAG--LAQCAHGCLNTQGSFKCVCHAGYELGADGRQ 323
C C G+ G+ CE D++EC + ++ + C+ + CVC + + GR
Sbjct: 1249 SCRCLPGFA----GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFT----GRH 1300
Query: 324 CYRI-----EMEIVNS-------------------------CEANNGG--CSHG--CSHT 349
C +M +N C+++ G C G C HT
Sbjct: 1301 CETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHT 1360
Query: 350 SAGPLCTCPRGYELDTDQRTCIDVDDCADSPC-----CQQVCTNNPGGYECGCYAGYRLS 404
++GP C CP R C CA SPC C P Y C C + S
Sbjct: 1361 ASGPRCFCP-------SPRDC--ESGCASSPCQHGGSCHP--QRQPPYYSCQCAPPF--S 1407
Query: 405 ADGCGCEDVDECASSRGGCEHHCTNLAGSFQC--SCEAGYRLHEDRRGCS-PLEEPMVDL 461
C +C + A C +C + + D CS +E P +
Sbjct: 1408 GSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNS-HACQWDGGDCSLTMENPWANC 1466
Query: 462 DGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCS 521
PLP + ++ +L + D E + + +K+ C D + C
Sbjct: 1467 SS------PLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKY-CADHFKDNHCD 1519
Query: 522 LTCDDCRNGGTCLLGLDGCDC 542
C N C G DG DC
Sbjct: 1520 QGC----NSEEC--GWDGLDC 1534
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 386 bits (992), Expect = e-107
Identities = 412/1437 (28%), Positives = 514/1437 (35%), Gaps = 304/1437 (21%)
Query: 133 CFHGGRCVPGSAQP--CHCPPGFQGPRCQYDVDECRT----HNGGCQHRCVNTP------ 180
C +GG C+ S C C PGF G CQ+ D C+ NGG + P
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 181 -----GSYLCECKPGFRLHTDSRTCLAI-NSCALGNGGCQHHCVQLTITRHRCQCRPGFQ 234
S+LC C PGF T R + + C + C R +C C PG+
Sbjct: 94 PSPLTPSFLCTCLPGF---TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGW- 149
Query: 235 LQEDGRHCVRR-----SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDE 288
G C R +PC N G C+ + +C C G+ +G ACE DV+E
Sbjct: 150 ---TGEQCQLRDFCSANPCVN-GGVCLATYPQI----QCHCPPGF----EGHACERDVNE 197
Query: 289 CAAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGC 346
C C G C NT GSF+C+C G E G +C +N G C
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTCQLMP 253
Query: 347 SHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECGC---YAGYR 402
S LC CP G+ + D ++ D+C C C + Y C C + G+
Sbjct: 254 EKDSTFHLCLCPPGF-IGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWD 310
Query: 403 LSADGCGCEDVDECASS------RGGCEHHCTNLAGSFQCSCEAGY---RLHEDRRGCSP 453
S EDVDEC + GG C N AGSF C C +G+ E+ C
Sbjct: 311 CS------EDVDECETQGPPHCRNGGT---CQNSAGSFHCVCVSGWGGTSCEENLDDCIA 361
Query: 454 LE----EPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKF 509
+D G + P P L L + D + + LT
Sbjct: 362 ATCAPGSTCIDRVGSFSCLCP-PGRTGLLCHLEDMCLSQPCHGDAQ----CSTNPLTGST 416
Query: 510 VCL--DDSFGHDCSLTCDD----------CRNGGTCL--LGLDGCDCPEGWTGLICNETC 555
+CL G C D+ C +GG+CL G C CP G+TG C
Sbjct: 417 LCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEA-- 474
Query: 556 PPDTFGKNCSFSCSCQNGGTCDSV--TGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNC 613
N S C G TC + T C CPPG+ G CE C C
Sbjct: 475 -----DHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE------VETNEC-ASAPC 522
Query: 614 ANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCV-QPHTQSCDKRDGS 670
N CH L C+C PG G C P C+ QC QP
Sbjct: 523 LNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP-CANGGQCQDQPGA-------FH 574
Query: 671 CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQE 730
C C GF G RCQ E + P CPVG +C + G CP+GF G+ C
Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDP-------CPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
Query: 731 -----------------------CPVGTFG-VNCSSSCSCGGAPCHGVTGQCRCPPGRTG 766
CP G+ G +C+C C C C G TG
Sbjct: 628 LCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQ--RSSCVCDVGWTG 685
Query: 767 EDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGP 824
+CEA+ GC I C H C P+ C C G+ G C + A GP
Sbjct: 686 PECEAELG------GC--ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 825 SCQTRCSCANDGHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSC 882
C N G C+P+ G +C+C P TG CQ + D P C + C G+
Sbjct: 738 -------CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP-CFNGGTCVNRPGTF 789
Query: 883 DAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAAC-DHVSG-ACTCPAGWRG 940
CLC G+ GPRCE G P C C++ A C D G C CP G+ G
Sbjct: 790 S-----CLCAMGFQGPRCE-----GKLRPSCAD-SPCRNRATCQDSPQGPRCLCPTGYTG 838
Query: 941 TFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAGRRGPRC---AETCPAHTY 995
C+ +D + C + C S CLC G GP C +C
Sbjct: 839 GSCQTL-------MDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAAL 891
Query: 996 GHNCSQACACFNGASC---DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGG 1052
+ C NG C P + CHC PG+ G C N S CQNG
Sbjct: 892 SQGIDVSSLCHNGGLCVDSGPSY-FCHCPPGFQGSLCQDHV-------NPCESRPCQNGA 943
Query: 1053 TC--DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPA 1108
TC P C C G+ G C KE C+ S C N G C P G C CP
Sbjct: 944 TCMAQPSGYLCQCAPGYDGQNCSKEL------DACQ-SQPCHNHGTCTPKPGGFHCACPP 996
Query: 1109 GWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGS 1166
G+ G +C+ G E Q C AACH + A C+C PG TG CE P
Sbjct: 997 GFVGLRCE-----GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP-C 1050
Query: 1167 FGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCG---CLN 1223
+ C C E A P C C G+ GP+C R P CG C +
Sbjct: 1051 HSQPCFHGGTC--EATAGSPLGFICHCPKGFEGPTCSHRAPS----------CGFHHCHH 1098
Query: 1224 GGSC-----DAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCL 1278
GG C C C +G+ G DC LT P + C C +C TG
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGYGGPDC-LTPPAPK---GCGPPSPCLYNGSCSETTGL-- 1152
Query: 1279 CPPGRAGVRCERGCPQNRFGVGCEHT----CSCRNG-GLCHASNGSCSCGLGWTGRHCEL 1333
G G RC CP + G C+ C R+G G C A G G W G C L
Sbjct: 1153 ---GGPGFRC--SCPHSSPGPRCQKPGAKGCEGRSGDGACDA--GCSGPGGNWDGGDCSL 1205
Query: 1334 ACPPGRYGAACHLEC-SCHNNSTCEPATGTCRCGPGFYGQACEHP--CPPGFHGAGCQGL 1390
P G H C + C P + C F G CE P C P +
Sbjct: 1206 GVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEEC--LFDGYDCETPPACTPAYDQ------ 1257
Query: 1391 CWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG 1447
C FH CE+GC C DGG C P G
Sbjct: 1258 ----------------YCHDHFHNGHCEKGCNTA--------ECGWDGG-DCRPEDG 1289
Score = 365 bits (937), Expect = e-100
Identities = 347/1241 (27%), Positives = 442/1241 (35%), Gaps = 328/1241 (26%)
Query: 520 CSLTCDDCRNGGTCL---LGLDGCDCPEGWTGLICNETCPPDTFGKNCSF--SCS----C 570
C + C NGGTCL LG C C G+ G+ C F C C
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGF-------------LGETCQFPDPCQNAQLC 74
Query: 571 QNGGTCDSVTGA----------------CRCPPGVSGTNC----EDGCPKGYYGKHCRKK 610
QNGG+C ++ A C C PG +G C ED CP +
Sbjct: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF-------- 126
Query: 611 CNCANRGRCHRLYGA---CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKR 667
C+ RGRCH C C PG G C L + C C+ + Q
Sbjct: 127 --CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLATYPQI---- 178
Query: 668 DGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDC 727
C C GF G C+ + + PG CP G +C + G CP G +G C
Sbjct: 179 --QCHCPPGFEGHACERDVNECFQDPG-----PCPKGTSCHNTLGSFQCLCPVGQEGPRC 231
Query: 728 ---GQECPVGTFGVNCSSSCSCGGAPCHGVTGQ-CRCPPGRTGEDCEADCPEGRWGLGCQ 783
CP CS+ +C P T C CPPG G DCE + P+ C
Sbjct: 232 ELRAGPCPPR----GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN-PD-----NC- 280
Query: 784 EICPACQHAARCDP--ETGACLCLPGFVGSRC-QDVCPAGWYGPSCQTRCSCANDGHCHP 840
+ CQ+ C +T CLC + G C +DV GP C N G C
Sbjct: 281 -VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-----HCRNGGTCQN 334
Query: 841 ATG--HCSCAPGWTGFSCQRACD-----TGHWGPDC-----SHPCNCSAG---------- 878
+ G HC C GW G SC+ D T G C S C C G
Sbjct: 335 SAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLED 394
Query: 879 -------HG----SCDAISG--LCLCEAGYVGPRCEQ---QCPQGHFGPGCEQRCQCQHG 922
HG S + ++G LCLC+ GY GP C Q +C GP C+HG
Sbjct: 395 MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPS-----PCEHG 449
Query: 923 AACDHVSGA--CTCPAGWRGTFCEH-------------------------ACPAGFFGLD 955
+C + G+ C CP G+ G+ CE CP G G
Sbjct: 450 GSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
Query: 956 CRSACNCTAGAAC-------DAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFN 1007
C N A A C D +NG C+C G G RC E ++ C N
Sbjct: 510 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDE-------CRSSPCAN 562
Query: 1008 GASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSG--HCAC 1063
G C G C C PG+ GP C D C S C G +C + G C C
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEV------DECL-SDPCPVGASCLDLPGAFFCLC 615
Query: 1064 PEGWAGLACE------KECLPRDVRAGCRHSGGCL----NGGLCDP------HTGR---- 1103
P G+ G CE C P+ + + CL + G P H G
Sbjct: 616 PSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS 675
Query: 1104 -CLCPAGWTGDKCQ--------SPCLRG--WFGEACAQRCSCP---PGAACHHVTGACRC 1149
C+C GWTG +C+ +PC G + + C+CP G C AC
Sbjct: 676 SCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHS 735
Query: 1150 PPGFTGSGCEQA-------CPPGSFGEDCAQMCQCPGENPACH-------PATGTCSCAA 1195
P G C + CPP G C P + P T +C CA
Sbjct: 736 GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAM 795
Query: 1196 GYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSC-DAATG-ACRCPTGFLGTDCNL---TCP 1250
G+ GP C+ G+ P C C N +C D+ G C CPTG+ G C C
Sbjct: 796 GFQGPRCE-----GKLRPSCAD-SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCA 849
Query: 1251 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCE---RGCPQNRFGVGCEHTCSC 1307
Q + P +H G + CLC G G C C + G + + C
Sbjct: 850 Q-KPCPRNSHCLQTGP-------SFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
Query: 1308 RNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECS------CHNNSTC--EPA 1359
NGGLC S S C CPPG G+ C + C N +TC +P+
Sbjct: 902 HNGGLCVDSGPSYFC-----------HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS 950
Query: 1360 TGTCRCGPGFYGQACEH-------------------------PCPPGFHGAGCQGLCWCQ 1394
C+C PG+ GQ C CPPGF G C+G
Sbjct: 951 GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC 1010
Query: 1395 HGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCD------CDGGAPCDPVTG- 1447
PC P +G C + + +C+ C PG G+ C D C G C+ G
Sbjct: 1011 LDQPCHP-TGTAACHSLANAFYCQ--CLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGS 1067
Query: 1448 ----LCLCPPGRSGATCNLDCRRGQFGPSCTL-HCDCGGGADCDPVSG---QCHCVDGYM 1499
+C CP G G TC+ PSC HC GG P G +C C+ GY
Sbjct: 1068 PLGFICHCPKGFEGPTCS------HRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYG 1121
Query: 1500 GPTCREGGPLR--LPENPSLAQGSAGTLPASSRPTSRSGGP 1538
GP C + P +P L GS P R P
Sbjct: 1122 GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCP 1162
Score = 352 bits (902), Expect = 2e-96
Identities = 349/1208 (28%), Positives = 426/1208 (35%), Gaps = 334/1208 (27%)
Query: 511 CLDDSFGHDCSL----TCDDCRNGGTCLLGLDG--CDCPEGWTGLICNET---------- 554
C+ G C L + + C NGG CL C CP G+ G C
Sbjct: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGP 204
Query: 555 CPPDTFGKNC--SFSC---------------------SCQNGGTC------DSVTGACRC 585
CP T N SF C C NGGTC DS C C
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 586 PPGVSGTNCE------------------DG-------CPKGYYGKHCRK---KC------ 611
PPG G +CE DG CP+ + G C + +C
Sbjct: 265 PPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP 324
Query: 612 NCANRGRCHRLYGA--CLCDPGLYGRFCH-------------------------LTCPPW 644
+C N G C G+ C+C G G C CPP
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Query: 645 AFGPGCSEECQCVQPHTQ-----SCDKRDGS--CSCKAGFRGERCQA---ECELGYFGPG 694
G C E C+ S + GS C C+ G+ G C EC + GP
Sbjct: 385 RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPS 444
Query: 695 CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHG- 753
C G +C + G CP G+ G C + C PCH
Sbjct: 445 -----PCEHGGSCLNTPGSFNCLCPPGYTGSRCE------------ADHNECLSQPCHPG 487
Query: 754 -------VTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETG-ACLCL 805
T C CPPG G+ CE + E C P HA D G C+CL
Sbjct: 488 STCLDLLATFHCLCPPGLEGQLCEVETNE------CAS-APCLNHADCHDLLNGFQCICL 540
Query: 806 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHC--HPATGHCSCAPGWTGFSCQRACDTG 863
PGF G+RC++ C++ CAN G C P HC C PG+ G CQ D
Sbjct: 541 PGFSGTRCEEDI------DECRS-SPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVD-- 591
Query: 864 HWGPDC-SHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQ----------------- 903
+C S PC A SC + G CLC +G+ G CE
Sbjct: 592 ----ECLSDPCPVGA---SCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQK 644
Query: 904 ------CPQGHFGPGC---EQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGL 954
CP G PGC E C C HG C S C C GW G CE
Sbjct: 645 DKANCLCPDG--SPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG----- 694
Query: 955 DCRSACNCTAGAAC--DAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCD 1012
C SA C G C +C CP G GP C+E A G C NG SC+
Sbjct: 695 -CISA-PCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG-------PCLNGGSCN 745
Query: 1013 PVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC--DPVSGHCACPEGWA 1068
P G C C P GP C + D C S C NGGTC P + C C G+
Sbjct: 746 PSPGGYYCTCPPSHTGPQCQTST------DYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQ 798
Query: 1069 GLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEAC 1128
G CE + P + CR+ C + P RCLCP G+TG CQ+ + C
Sbjct: 799 GPRCEGKLRPSCADSPCRNRATCQD----SPQGPRCLCPTGYTGGSCQT------LMDLC 848
Query: 1129 AQRCSCPPGAACHHVTGA---CRCPPGFTG-------SGCEQACPPGSFGEDCAQMCQCP 1178
AQ+ CP + C TG C C G+TG S C++A S G D + +C
Sbjct: 849 AQK-PCPRNSHCLQ-TGPSFHCLCLQGWTGPLCNLPLSSCQKAAL--SQGIDVSSLCHNG 904
Query: 1179 GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRC 1236
G P+ C C G+ G CQ P P C NG +C A C+C
Sbjct: 905 GLCVDSGPSY-FCHCPPGFQGSLCQDHVNPCESRP-------CQNGATCMAQPSGYLCQC 956
Query: 1237 PTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLCPPGRAGVRCERGCPQ 1294
G+ G +C+ + P C C P G C CPPG G+RCE +
Sbjct: 957 APGYDGQNCSKELDACQSQP-------CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDE 1009
Query: 1295 NRFGVGCEHTCSCRNGGLCH--ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHN 1352
+ C CH A+ C C G TG+ CE+ P CH + C +
Sbjct: 1010 -----CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP------CHSQ-PCFH 1057
Query: 1353 NSTCEPATGT-----CRCGPGFYGQACEHPCPP-GFHGAGCQGLCWCQHGAPCDP----- 1401
TCE G+ C C GF G C H P GFH C HG C P
Sbjct: 1058 GGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH--------HCHHGGLCLPSPKPG 1109
Query: 1402 ISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGL------CLCPPGR 1455
RC C +G+ G C P +GC C C TGL C CP
Sbjct: 1110 FPPRCACLSGYGGPDCLTPPAP----KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSS 1165
Query: 1456 SGATCNLDCRRGQFGPSCTLHCDCG--------GGADC-----DPVSG-----QCHCV-- 1495
G C +G G S CD G G DC DP G +C +
Sbjct: 1166 PGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFR 1225
Query: 1496 DGYMGPTC 1503
DG P C
Sbjct: 1226 DGQCHPQC 1233
Score = 347 bits (891), Expect = 4e-95
Identities = 364/1301 (27%), Positives = 465/1301 (35%), Gaps = 302/1301 (23%)
Query: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQ-PCHCPPGFQGPRCQYDVDECRTH 168
C GW E+ L CSA+ C +GG C+ Q CHCPPGF+G C+ DV+EC
Sbjct: 145 CMPGWT---GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQD 201
Query: 169 NGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTCLAINSC---ALGNGGCQHHCVQLTIT 223
G C C NT GS+ C C G R L C NGG + T
Sbjct: 202 PGPCPKGTSCHNTLGSFQCLCPVG---QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDST 258
Query: 224 RHRCQCRPGF---QLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADG 280
H C C PGF + + +CV C N G+C L E G+ +
Sbjct: 259 FHLCLCPPGFIGPDCEVNPDNCVSHQ-CQN-GGTCQDGLDTYTCLCP-ETWTGWDCS--- 312
Query: 281 KACEDVDEC-AAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 337
EDVDEC G C +G C N+ GSF CVC +G+ G C E ++ C A
Sbjct: 313 ---EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSC----EENLDDCIA 361
Query: 338 NNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQV-CTNNP--GGYE 394
C C CP G C D C PC C+ NP G
Sbjct: 362 ATCAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTL 417
Query: 395 CGCYAGYRLSADGCGCEDVDECASSRGG---CEH--HCTNLAGSFQCSCEAGY---RLHE 446
C C GY S C +D+DEC ++ G CEH C N GSF C C GY R
Sbjct: 418 CLCQPGY--SGPTCH-QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEA 474
Query: 447 DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLT 506
D C L +P P L +A P G + + E+ +
Sbjct: 475 DHNEC--LSQPC------HPGSTCLDLLATFHCLCPP-------GLEGQLCEVETNECAS 519
Query: 507 EKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSF 566
CL+ + C D NG C+ C G++G C E C
Sbjct: 520 AP--CLNHA-------DCHDLLNGFQCI-------CLPGFSGTRCEEDI------DECR- 556
Query: 567 SCSCQNGGTCDSVTGA--CRCPPGVSGTNCE--------DGCPKGYYGKHCRKKCNCANR 616
S C NGG C GA C+C PG G C+ D CP G
Sbjct: 557 SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG--------------- 601
Query: 617 GRCHRLYGA--CLCDPGLYGRFCHL------TCPPWAFGPGCSEECQCVQPH-TQSCDKR 667
C L GA CLC G G+ C + C P ++ C+ P + C
Sbjct: 602 ASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPP 661
Query: 668 DGSCSCKAGFRGERCQAECELGYFGPGCWQ------ACTCPVGVACDSVSGECGKRCPAG 721
+ +C+C G +R C++G+ GP C + C G C CP G
Sbjct: 662 EDNCTCHHG-HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 722 FQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPGRTGEDCEADCPEGRWG 779
+ G C +E C S G C+ G C CPP TG C+
Sbjct: 721 YTGPTCSEEMTA------CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY---- 770
Query: 780 LGCQEICPACQHAARC--DPETGACLCLPGFVGSRCQD---------------------- 815
C + C + C P T +CLC GF G RC+
Sbjct: 771 --C--VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQ 826
Query: 816 ----VCPAGWYGPSCQT------RCSCANDGHCHPA--TGHCSCAPGWTG-------FSC 856
+CP G+ G SCQT + C + HC + HC C GWTG SC
Sbjct: 827 GPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSC 886
Query: 857 QRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR 916
Q+A + G D S C+ + G S C C G+ G C Q H P CE R
Sbjct: 887 QKAALS--QGIDVSSLCH-NGGLCVDSGPSYFCHCPPGFQGSLC-----QDHVNP-CESR 937
Query: 917 CQCQHGAAC-DHVSG-ACTCPAGWRGTFCEH-------------------------ACPA 949
CQ+GA C SG C C G+ G C ACP
Sbjct: 938 -PCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 950 GFFGLDCR--------SACNCTAGAACDAVNGS--CLCPAGRRGPRC-AETCPAHTYGHN 998
GF GL C C+ T AAC ++ + C C G G C E P H+
Sbjct: 997 GFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQ--- 1053
Query: 999 CSQACACFNGASCDPVHGQ-----CHCAPGWMGPSCLQACPA-GLYGDNCRHSCLCQNGG 1052
CF+G +C+ G CHC G+ GP+C P+ G + C +GG
Sbjct: 1054 -----PCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHH--------CHHGG 1100
Query: 1053 TCDP-----VSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG----- 1102
C P CAC G+ G +CL GC CL G C TG
Sbjct: 1101 LCLPSPKPGFPPRCACLSGYGG----PDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG 1156
Query: 1103 -RCLCPAGWTGDKCQSPCLRGWFGE----ACAQRCSCPPGAACHHVTGACRCPPGFTGSG 1157
RC CP G +CQ P +G G AC CS P G + G
Sbjct: 1157 FRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGG--------------NWDGGD 1202
Query: 1158 CEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQ 1217
C P G C + CHP + C + G C+ P P +Q
Sbjct: 1203 CSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL--FDGYDCE---TPPACTPAYDQ 1257
Query: 1218 LC-GCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPN 1257
C + G C+ C G+ G DC +GP+
Sbjct: 1258 YCHDHFHNGHCEKGCNTAEC--GWDGGDCRPEDGDPEWGPS 1296
Score = 299 bits (765), Expect = 2e-80
Identities = 305/1113 (27%), Positives = 370/1113 (33%), Gaps = 389/1113 (34%)
Query: 737 GVNCSS---SCSCGGAPCHGVT---GQCRCPPGRTGEDCEAD--CPEGRW---GLGCQEI 785
G+ C S C+ GG C ++ G C+C PG GE C+ C + G CQ +
Sbjct: 25 GLLCGSFPEPCANGGT-CLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQAL 83
Query: 786 CPA-CQHAARCDPETGA--CLCLPGFVGSRCQ----DVCPAGWYGPSCQTRCSCANDGHC 838
PA + P T + C CLPGF G RCQ D CP + C+ G C
Sbjct: 84 LPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF----------CSKRGRC 133
Query: 839 H-PATGH--CSCAPGWTGFSCQRA------------------------CDTGHWGPDCSH 871
H A+G CSC PGWTG CQ C G G C
Sbjct: 134 HIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER 193
Query: 872 PCN-CSAGHGSCDAISGL--------CLCEAGYVGPRCEQQ------------------- 903
N C G C + CLC G GPRCE +
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMP 253
Query: 904 ----------CPQGHFGPGCE---QRC---QCQHGAACDH--VSGACTCPAGWRGTFCEH 945
CP G GP CE C QCQ+G C + C CP W G C
Sbjct: 254 EKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSE 313
Query: 946 ----------------------------ACPAGFFGLDCRS------ACNCTAGAAC-DA 970
C +G+ G C A C G+ C D
Sbjct: 314 DVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 971 VNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQ--CHCAPGWMGP 1027
V SCLCP GR G C H SQ C S +P+ G C C PG+ GP
Sbjct: 374 VGSFSCLCPPGRTGLLC------HLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP 427
Query: 1028 SCLQ------------------------------ACPAGLYGDNC---RHSCL---CQNG 1051
+C Q CP G G C + CL C G
Sbjct: 428 TCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPG 487
Query: 1052 GTCDPV--SGHCACPEGWAGLACEKE-------------------------CLPRDVRAG 1084
TC + + HC CP G G CE E CLP
Sbjct: 488 STCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTR 547
Query: 1085 CR------HSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPP 1136
C S C NGG C G C C G+ G +CQ+ + C CP
Sbjct: 548 CEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV------DECLSD-PCPV 600
Query: 1137 GAACHHVTGA--CRCPPGFTGSGCE------QACPPGSFGEDCAQM--CQCPGENPACHP 1186
GA+C + GA C CP GFTG CE C P +D C CP +P C P
Sbjct: 601 GASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAP 660
Query: 1187 ATGTCSCAAGYHGPSCQQR---CPPGRYGPGCEQLCG------CLNGGSCDAATGA--CR 1235
C+C +HG CQ+ C G GP CE G C +GG+C C
Sbjct: 661 PEDNCTC---HHG-HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCT 716
Query: 1236 CPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLCPPGRAGVRCERGCP 1293
CPTG+ G C+ GP C G +C+P G C CPP G +C+
Sbjct: 717 CPTGYTGPTCSEEMTACHSGP-------CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTD 769
Query: 1294 QNRFGVGCEHTCSCRNGGLCHASNG--SCSCGLGWTGRHCELACPPGRYGAACHLECSCH 1351
C + C NGG C G SC C +G+ G CE G+ +C + C
Sbjct: 770 Y------CV-SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE-----GKLRPSC-ADSPCR 816
Query: 1352 NNSTCE--PATGTCRCGPGFYGQAC--------EHPCP---------PGFHGAGCQG--- 1389
N +TC+ P C C G+ G +C + PCP P FH QG
Sbjct: 817 NRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTG 876
Query: 1390 -LC--------------------WCQHGAPC--DPISGRCLCPAGFHGHFCER------- 1419
LC C +G C S C CP GF G C+
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCES 936
Query: 1420 ------------------GCEPGSFGEGCHQRCD------CDGGAPCDPVTG--LCLCPP 1453
C PG G+ C + D C C P G C CPP
Sbjct: 937 RPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 1454 GRSGATCNLD---------------------------CRRGQFGPSCTLHCD------CG 1480
G G C D C G G C + D C
Sbjct: 997 GFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF 1056
Query: 1481 GGADCDPVSGQ-----CHCVDGYMGPTCREGGP 1508
G C+ +G CHC G+ GPTC P
Sbjct: 1057 HGGTCEATAGSPLGFICHCPKGFEGPTCSHRAP 1089
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 338 bits (868), Expect = 2e-92
Identities = 409/1525 (26%), Positives = 544/1525 (35%), Gaps = 303/1525 (19%)
Query: 161 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGC-QHHCV 218
DV+EC+ G C H C NT GS+ C C GF L R C I+ C + C Q CV
Sbjct: 986 DVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 219 QLTITRHRCQCRPGFQLQEDG----RHCVRRSPCAN-----RNGSCMHRCQVVRGLARCE 269
T C+C PG+ E G ++C+ CA R G+C + G +C+
Sbjct: 1046 N-TPGSFECECFPGY---ESGFMLMKNCMDVDECARDPLLCRGGTCTN----TDGSYKCQ 1097
Query: 270 CHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIE 328
C G++L A G ACED+DEC+ C HG C+N G+F+C CHAG++ D + C I
Sbjct: 1098 CPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDI- 1156
Query: 329 MEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVC 386
N C NGGC C +T C+C +GY L D R C DVD+C ++P C Q C
Sbjct: 1157 ----NECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHC 1212
Query: 387 TNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLH 445
TN PGG+ C CY G+ + D C DVDEC + C H C N GSF C C+ GY +
Sbjct: 1213 TNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVR 1272
Query: 446 EDRRGCSPLEEPMV---DLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGE 502
+ GCS ++E V + D + +P + LP D D +E + E
Sbjct: 1273 KGATGCSDVDECEVGGHNCDSHASCLN-IPGSFSCRC-LPGWVGDGFECHDLDEC-VSQE 1329
Query: 503 HTLTEKFVCLDDSFGHDCSLTCDD--------CRNGGTCLLGLDGCD------CPEGWTG 548
H + + CL+ + C TC C + C +D CD P G+
Sbjct: 1330 HRCSPRGDCLNVPGSYRC--TCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYR- 1386
Query: 549 LICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCR 608
C P + C C G C G+C PG+ C G G +C
Sbjct: 1387 CECEMGFDPTEDHRACQDVDECAQGNLC--AFGSCENLPGMFRCICNGGYELDRGGGNCT 1444
Query: 609 KKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRD 668
CA+ C + G C+ PG Y C G GC + + ++ D+ D
Sbjct: 1445 DINECADPVNC--INGVCINTPGSYLCSCPQDFELNPSGVGC-VDTRAGNCFLETHDRGD 1501
Query: 669 G--SCSCKAGFRGERCQAECELGYFGPG----CWQACTCPVGVACDSVSGECGKRCPAGF 722
SCS + G R C LG C A T C G R
Sbjct: 1502 SGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVIL 1561
Query: 723 QGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPG-RTGEDCEADCPEGRWG 779
+ D QE P G+ C G C G QC CPPG E
Sbjct: 1562 EDIDECQELP----GL-------CQGGDCVNTFGSFQCECPPGYHLSEHTRI-------- 1602
Query: 780 LGCQEICPACQHAARCDPET-------GACLCLPGFV----GSRCQD----VCPAGWYGP 824
C++I H+ C P T C+C ++ G+ C D VC + G
Sbjct: 1603 --CEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNG- 1659
Query: 825 SCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDT--GHWGPDCSHPCNCSA----- 877
+C N+ + C C+ G + R C+ PD C A
Sbjct: 1660 ------TCQNELAFNVTRKMCCCSYN-IGQAWNRPCEACPTPISPDYQILCGNQAPGFLT 1712
Query: 878 -------------GHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQ------ 918
G +G+C+ + G RCE CP G C+
Sbjct: 1713 DIHTGKPLDIDECGEIPAICANGICINQIGSF--RCE--CPAGFNYNSILLACEDVDECG 1768
Query: 919 -----CQHGAACDHVSGA--CTCPAGWRGTFCEHACPAG--FFGLDCRSACNCTAGAACD 969
CQ A C ++ G+ C C G++ P G +CR N + C
Sbjct: 1769 SRESPCQQNADCINIPGSYRCKCTRGYK------LSPGGACVGRNECREIPNVCSHGDCM 1822
Query: 970 AVNGS--CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGWM 1025
GS CLC G + C C + C NG +C + G C C PG++
Sbjct: 1823 DTEGSYMCLCHRGFQASADQTLCMDI---DECDRQ-PCGNG-TCKNIIGSYNCLCFPGFV 1877
Query: 1026 ---GPSCL--QACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRD 1080
C+ C L G CR G S HC C +G+ A K C+ D
Sbjct: 1878 VTHNGDCVDFDECTT-LVGQVCRFGHCLNTAG-----SFHCLCQDGFELTADGKNCV--D 1929
Query: 1081 VRAGCRHSGGCLNGGLCDPHTG--RCLCPAGW--TGDKCQSPCLRGWFGEACAQRCSCPP 1136
+G CL G C G RC+CP G+ D C + C++ +
Sbjct: 1930 TNECLSLAGTCL-PGTCQNLEGSFRCICPPGFQVQSDHCIDI-------DECSEEPNLCL 1981
Query: 1137 GAACHHVTGA--CRCPPGF----TGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT 1190
C + G+ C CPPGF G C F A C P A +
Sbjct: 1982 FGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP---KAFNTTKTR 2038
Query: 1191 CSCA----AGYHGP----------SCQQRCPPGRYG-PG----------CEQLCGCLNGG 1225
C C+ G+ P + Q+ CP G PG C + G G
Sbjct: 2039 CCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNG 2098
Query: 1226 SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAG 1285
C G+ RC F G + T G NC C G C GTC G
Sbjct: 2099 VCVNTDGSFRCECPF-GYSLDFT------GINCVDTDECSVGHPCG--QGTCTNVIGGFE 2149
Query: 1286 VRCERGCPQNRFGVGCEHTCSCRNGGL-----CHASNGS--CSCGLGWTGRHCELACPPG 1338
C G + CE C L CH + GS C+C G+T R C
Sbjct: 2150 CACADGFEPGLM-MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDV 2208
Query: 1339 RYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFH-----GAGCQGLCWC 1393
A +C C+ GT C CPPG G GC C
Sbjct: 2209 DECADGQQDCHA-RGMECKNLIGTFAC-----------VCPPGMRPLPGSGEGCTDDNEC 2256
Query: 1394 QHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQ--------------------- 1432
H P ++GRC+ AG C+ G +P CH
Sbjct: 2257 -HAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSS 2315
Query: 1433 -------RCDCDGGAPCDPVTGLC----------LCPPGRSGATCNLDCRRGQFGPSCTL 1475
C C GG P LC LCP G SG T G+ C +
Sbjct: 2316 SEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTA-----EGRDVDECRM 2369
Query: 1476 HCDCGGGADCDPVSG--QCHCVDGY 1498
+C G +CHC GY
Sbjct: 2370 LAHLCAHGECINSLGSFRCHCQAGY 2394
Score = 306 bits (783), Expect = 1e-82
Identities = 458/1715 (26%), Positives = 585/1715 (34%), Gaps = 430/1715 (25%)
Query: 110 CCRGWMQQPDEEGCLSA-EC--SASLCFHGGRCV--PGSAQPCHCPPGFQG-----PRCQ 159
C G+ E C EC S LC G CV PGS + C C PG++ C
Sbjct: 1013 CAGGFALDAQERNCTDIDECRISPDLCGQG-TCVNTPGSFE-CECFPGYESGFMLMKNCM 1070
Query: 160 YDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH-HC 217
DVDEC C+ C NT GSY C+C PG L C I+ C+L +G C H C
Sbjct: 1071 -DVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 218 VQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLA 277
V + I +C C GFQ D + CV + C +NG C C G RC C GY L
Sbjct: 1130 VNV-IGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLM 1188
Query: 278 ADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCE 336
DG+AC DVDEC C G C N G +C+C+ G+ D R C V+ C+
Sbjct: 1189 PDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVD-----VDECD 1243
Query: 337 ANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC------ADS---------- 379
N C HG C +T +C C GY + C DVD+C DS
Sbjct: 1244 LNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS 1303
Query: 380 --------------------PCCQQV--------CTNNPGGYECGCYAGYRLSADGCGCE 411
C Q C N PG Y C C G+ + DG CE
Sbjct: 1304 FSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF--AGDGFFCE 1361
Query: 412 DVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRP 470
D DECA + C++ C N G ++C CE G+ ED R C ++E G L
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDE---CAQGNLCAFGS 1418
Query: 471 LPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNG 530
+ LP +F+ G E + RG T+ C D +C N
Sbjct: 1419 C-------ENLPGMFRCICNGGYELD---RGGGNCTDINECADPV----------NCIN- 1457
Query: 531 GTCL--LGLDGCDCPEGW----TGLICNET----CPPDTFGKNCS-FSCSCQNG------ 573
G C+ G C CP+ + +G+ C +T C +T + S SCS + G
Sbjct: 1458 GVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 574 GTCDSVTGA----CRCPPGVSGTNCEDGCPKGYYGK------------HCRKKCNCANRG 617
C S+ A C P + T CP G + C++ G
Sbjct: 1518 SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGG 1577
Query: 618 RCHRLYGA--CLCDPGL----YGRFC----HLTCPPWAFGPG------------CSEECQ 655
C +G+ C C PG + R C + GPG C E
Sbjct: 1578 DCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYL 1637
Query: 656 CVQPHTQSCDKR--------DGSCSCKAGFRGER--CQAECELGYFGPGCWQACTCPV-- 703
V D R +G+C + F R C +G +AC P+
Sbjct: 1638 QVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISP 1697
Query: 704 -----------GVACDSVSG------ECGK---RCPAGFQGEDCGQ---ECPVGTFGVN- 739
G D +G ECG+ C G G ECP G F N
Sbjct: 1698 DYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAG-FNYNS 1756
Query: 740 ----CSSSCSCG--------GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICP 787
C CG A C + G RC R + GR C+EI
Sbjct: 1757 ILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGR--NECREIPN 1814
Query: 788 ACQHAARCDPE-TGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATG--H 844
C H D E + CLC GF S Q +C C R C N G C G +
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLC---MDIDECD-RQPCGN-GTCKNIIGSYN 1869
Query: 845 CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQC 904
C C PG+ H G DC C+ G G CL AG C+
Sbjct: 1870 CLCFPGFV---------VTHNG-DCVDFDECTTLVGQVCRF-GHCLNTAGSFHCLCQDGF 1918
Query: 905 PQGHFGPGCEQRCQCQHGA------ACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDC 956
G C +C A C ++ G+ C CP G++ +H +C
Sbjct: 1919 ELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQ-VQSDHCIDID----EC 1973
Query: 957 RSACNCTAGAACDAVNGS--CLCPAG----RRGPRCAETCPAHTYGHNCSQACACFNGAS 1010
N C GS CLCP G G RC +T ++ +A C +
Sbjct: 1974 SEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDT--RQSFCFTRFEAGKCSVPKA 2031
Query: 1011 CDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGL 1070
+ +C C P +GD C LC G+ + CP G G
Sbjct: 2032 FNTTKTRC----------CCSKRPGEGWGDPCE---LCPQEGS---AAFQELCPFG-HGA 2074
Query: 1071 ACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGW----TG------DKCQ-- 1116
+ DV + G C N G+C G RC CP G+ TG D+C
Sbjct: 2075 VPGPDDSREDVNECAENPGVCTN-GVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG 2133
Query: 1117 SPC-------LRGWFGEACA--------------QRCSCPP---GAACHHVTGA--CRCP 1150
PC + G F ACA CS P CH+ G+ C CP
Sbjct: 2134 HPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCP 2193
Query: 1151 PGFT----GSGCEQACPPGSFGEDCAQMCQ-CPGENPACHPATGTCSCAAGYHGPSCQQR 1205
G+T G+ C ++CA Q C C GT +C
Sbjct: 2194 AGYTLREDGAMCRDV-------DECADGQQDCHARGMECKNLIGTFACV----------- 2235
Query: 1206 CPPG-RYGPGCEQLCG-----------CLNGGSCD-AATGACRCPTGFLGTDCNLTCPQG 1252
CPPG R PG + C C+NG + A + C C GF + C
Sbjct: 2236 CPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI 2295
Query: 1253 RFGPNCTHV----CGCGQGAACDPVTGTCLCPPGRA-GVRCERGCP---QNRFGVGCEH- 1303
R GP V C ++ C C GR G RCE CP + + C H
Sbjct: 2296 RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCEL-CPLPGTSAYRKLCPHG 2354
Query: 1304 ---TCSCRNGGLCH-----ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHN--- 1352
T R+ C ++G C LG HC+ P C C
Sbjct: 2355 SGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPK 2414
Query: 1353 --NSTCEPATGT--CRCGPGFY----GQACEH------------------------PCPP 1380
C+ G+ C C G+ G+ C+ CPP
Sbjct: 2415 PCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPP 2474
Query: 1381 GF--HGAGC--QGLCWCQHGAPC--------DPISGRCLCPAGF----HGHFCE--RGCE 1422
GF H C C Q G PC P S RC C GF GH CE C+
Sbjct: 2475 GFTQHHQACFDNDECSAQPG-PCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD 2533
Query: 1423 -PGSFGEGCHQ-----RCDCDGG-------APCDPVTGLCLCPPGRSGATCNLDCRRGQF 1469
P GC RC C G A C L PP A+C R
Sbjct: 2534 GPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC-----RNTL 2588
Query: 1470 GPSCTLHCDCGGGADCDPVSGQCHCVD---GYMGP 1501
G C C G D D G C VD G GP
Sbjct: 2589 G---GFRCVCPSGFDFDQALGGCQEVDECAGRRGP 2620
Score = 278 bits (712), Expect = 2e-74
Identities = 431/1651 (26%), Positives = 558/1651 (33%), Gaps = 382/1651 (23%)
Query: 109 RCCRGWMQQPDEEGCLSA-EC--SASLCFHGGRCV--PGSAQPCHCPPGFQ----GPRCQ 159
RC G+ P + C+ EC S LC H GRCV GS Q C C GF+ G C
Sbjct: 473 RCYPGFQATPTRQACVDVDECIVSGGLC-HLGRCVNTEGSFQ-CVCNAGFELSPDGKNC- 529
Query: 160 YDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 219
D +EC T C+N GS+ C CKPGF L C+ I+ C HC
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTN 589
Query: 220 LTITRHRCQCRPGFQLQEDGRHCVR---RSPC--ANRNGSCMHR---------------- 258
T RCQC G + DGR CV RS C A GSC
Sbjct: 590 -TEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPD 648
Query: 259 ------CQVVRGLARCE----CHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSF 307
CQ+ E C G + DG+ D++ECA CA+G C N +GS+
Sbjct: 649 HGFGEPCQLCPAKDSAEFQALCSSGLGITTDGR---DINECALDPEVCANGVCENLRGSY 705
Query: 308 KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQ 367
+CVC+ GYE GA G+ C ++ +NS +NG C + S C+CP G+ D
Sbjct: 706 RCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYS----CSCPPGFHFWQDT 761
Query: 368 RTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVD------------- 414
C DVD+C SPC VC N G Y C C G RL G C D
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRC 821
Query: 415 ----ECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRG--------CSPLEEPMVDLD 462
+ AS R C C L ++ CE RG C + E
Sbjct: 822 EVNLQGASLRSEC---CATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNE-CESFP 877
Query: 463 GELPFVRPLPHIAVLQDELPQLFQDDDVGA--------------DEEE--AELRGEHTLT 506
G P R + + E P+ D G DE+E L G++ +
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMD 937
Query: 507 EKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKN--- 563
+ +G +C C D + L CP G G + F K+
Sbjct: 938 VCCCSIGAVWGVECE-ACPDPESLEFASL------CPRG-LGFASRDFLSGRPFYKDVNE 989
Query: 564 CSFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHR 621
C GTC + G+ C C G + E C CR + +G C
Sbjct: 990 CKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD---IDECRISPDLCGQGTCVN 1046
Query: 622 LYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP----HTQSCDKRDGS--CSC 673
G+ C C PG F + C + +C + +C DGS C C
Sbjct: 1047 TPGSFECECFPGYESGFMLM--------KNCMDVDECARDPLLCRGGTCTNTDGSYKCQC 1098
Query: 674 KAGF----RGERCQ--AECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDC 727
G +G C+ EC L CP G C +V G C AGFQ
Sbjct: 1099 PPGHELTAKGTACEDIDECSL--------SDGLCPHG-QCVNVIGAFQCSCHAGFQSTPD 1149
Query: 728 GQ------ECPV--GTFGVNC-----SSSCSCG--------GAPCHGV-----------T 755
Q EC V G V+C S CSCG G C V
Sbjct: 1150 RQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQ 1209
Query: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEIC----------PACQHAARCDPETGA--CL 803
G C PG G C C +G C C H C+ G+ C
Sbjct: 1210 GHCTNMPG--GHRCL--CYDGFMATPDMRTCVDVDECDLNPHICLH-GDCENTKGSFVCH 1264
Query: 804 CLPGFV----GSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWT--GFSCQ 857
C G++ + C DV G +C + SC N P + C C PGW GF C
Sbjct: 1265 CQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLN----IPGSFSCRCLPGWVGDGFEC- 1319
Query: 858 RACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQ 915
H +C + + G C + G C C G+ G G F CE
Sbjct: 1320 ------HDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG--------DGFF---CED 1362
Query: 916 RCQCQHGA-ACDHVSGAC-TCPAGWRGTFCEHACPAGFFGLDCRSAC----NCTAGAACD 969
R +C CD +G C P G+R CE C GF + AC C G C
Sbjct: 1363 RDECAENVDLCD--NGQCLNAPGGYR---CE--CEMGFDPTEDHRACQDVDECAQGNLC- 1414
Query: 970 AVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC 1029
GSC G C G NC+ C + +C ++G C PG S
Sbjct: 1415 -AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNC--INGVCINTPG----SY 1467
Query: 1030 LQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSG 1089
L +CP + C+ G C + H G +G++C E RA C S
Sbjct: 1468 LCSCPQDFELNPSGVGCVDTRAGNCF-LETH---DRGDSGISCSAEIGVGVTRASCCCSL 1523
Query: 1090 GCLNGGLCD--PHTG----RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHV 1143
G G C+ P R LCP G + + E C + G C +
Sbjct: 1524 GRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDE-CQELPGLCQGGDCVNT 1582
Query: 1144 TGA--CRCPPGFTGSG----CEQ---------ACPPGSFGEDCAQ-MCQCPGE------- 1180
G+ C CPPG+ S CE C PG+ C CP E
Sbjct: 1583 FGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGG 1642
Query: 1181 --------NPACHPATGTCS-----------CAAGYH-GPSCQQRCP--PGRYGPGCEQL 1218
+ GTC C Y+ G + + C P P + L
Sbjct: 1643 NNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQIL 1702
Query: 1219 CG---------------------------CLNGGSCDAATGA--CRCPTGFLGTDCNLTC 1249
CG C N G C G+ C CP GF L C
Sbjct: 1703 CGNQAPGFLTDIHTGKPLDIDECGEIPAICAN-GICINQIGSFRCECPAGFNYNSILLAC 1761
Query: 1250 PQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR- 1308
V CG + C+ PG +C RG + G C CR
Sbjct: 1762 ED---------VDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSP-GGACVGRNECRE 1811
Query: 1309 -----NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEP-ATGT 1362
+ G C + GS C C G +A C + +P GT
Sbjct: 1812 IPNVCSHGDCMDTEGSYMC-----------LCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 1363 CRCGPGFYGQACEHPCPPGF---HGAGCQGL--CWCQHGAPCDPISGRCLCPAGFHGHFC 1417
C+ G Y C PGF H C C G C G CL AG C
Sbjct: 1861 CKNIIGSYNCLCF----PGFVVTHNGDCVDFDECTTLVGQVCR--FGHCLNTAGSFHCLC 1914
Query: 1418 ERGCEPGSFGEGCHQRCDCDGGA------PCDPVTG--LCLCPPGRSGATCN-LDCRRGQ 1468
+ G E + G+ C +C A C + G C+CPPG + + +D
Sbjct: 1915 QDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECS 1974
Query: 1469 FGPSCTLHCDCGGGADCDPVSGQCHCVDGYM 1499
P+ L C P S QC C G++
Sbjct: 1975 EEPNLCLFGTCTN----SPGSFQCLCPPGFV 2001
Score = 271 bits (693), Expect = 4e-72
Identities = 398/1512 (26%), Positives = 517/1512 (34%), Gaps = 308/1512 (20%)
Query: 102 TEARTVLRCCRGWMQQPDEEGCLSA---ECSASLCFHGGRC--VPGSAQPCHCPPGFQGP 156
T+ V C G+M + GC E C C +PGS C C PG+ G
Sbjct: 1257 TKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFS-CRCLPGWVGD 1315
Query: 157 RCQ-YDVDECRTHNGGCQHR--CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGC 213
+ +D+DEC + C R C+N PGSY C C+ GF D C + CA C
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLC 1373
Query: 214 QHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVG 273
+ +RC+C GF ED R C CA N C+ + G+ RC C+ G
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGG 1433
Query: 274 YQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIV 332
Y+L G C D++ECA + C +G C+NT GS+ C C +EL G C ++
Sbjct: 1434 YELDRGGGNCTDINECADPV-NCINGVCINTPGSYLCSCPQDFELNPSGVGC--VDTRAG 1490
Query: 333 N-------------SCEANNG--------GCSHGCSHTSAGPLC----------TCPRGY 361
N SC A G CS G + + LC CP G
Sbjct: 1491 NCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGE 1550
Query: 362 ELDTDQRTCI--DVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 417
++ T I D+D+C + P C C N G ++C C GY LS CED+DEC+
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECS 1610
Query: 418 SSRGGC-EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAV 476
+ G C C N G++ C C A Y C +D+ + F +
Sbjct: 1611 THSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNC-------MDMRKSVCFRH---YNGT 1660
Query: 477 LQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNG-GTCLL 535
Q+EL +T K C + G + C+ C
Sbjct: 1661 CQNEL--------------------AFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQ 1700
Query: 536 GLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGA--CRCPPGVSGTN 593
L G P T + + D G+ C N G C + G+ C CP G + +
Sbjct: 1701 ILCGNQAPGFLTDIHTGKPLDIDECGE---IPAICAN-GICINQIGSFRCECPAGFNYNS 1756
Query: 594 ----CEDGCPKGYYGKHCRKKCNCAN-----RGRCHRLY--------------------- 623
CED G C++ +C N R +C R Y
Sbjct: 1757 ILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC 1816
Query: 624 --GACLCDPGLYGRFCHLTCPPWAFGPGCS--EECQCVQPHTQSCDKRDGS--CSCKAGF 677
G C+ G Y CH A C +EC +C GS C C GF
Sbjct: 1817 SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGF 1876
Query: 678 RGERCQAECELGYFGPGCWQACTCPVGVACD-----SVSGECGKRCPAGFQGEDCGQECP 732
+C + CT VG C + +G C GF+ G+ C
Sbjct: 1877 VVTH-NGDCV-------DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV 1928
Query: 733 VGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPG-RTGEDCEADCPEGRWGLGCQEICPAC 789
++ + +C G C + G +C CPPG + D D E C E C
Sbjct: 1929 DTNECLSLAGTCLPG--TCQNLEGSFRCICPPGFQVQSDHCIDIDE------CSEEPNLC 1980
Query: 790 QHAARCD-PETGACLCLPGFV----GSRC----QDVCPAGWYGPSC---------QTRCS 831
+ P + CLC PGFV G RC Q C + C +TRC
Sbjct: 1981 LFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCC 2040
Query: 832 CANDGHCHPATG---HCSCAPGWTGFSCQRACDTGHW---GPDCSHP--CNCSAGHGSCD 883
C+ P G C P + Q C GH GPD S C+ G C
Sbjct: 2041 CSK----RPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC- 2095
Query: 884 AISGLCLCEAGYVGPRCEQQCPQGH----FGPGCEQRCQCQHGAACDHVSGACTCPAGWR 939
+G+C+ G RCE CP G+ G C +C G C G CT G
Sbjct: 2096 -TNGVCVNTDGSF--RCE--CPFGYSLDFTGINCVDTDECSVGHPCG--QGTCTNVIG-- 2146
Query: 940 GTFCEHACPAGF---FGLDCRSACNCT-----AGAACDAVNGS--CLCPAG----RRGPR 985
G C AC GF + C C+ C GS C CPAG G
Sbjct: 2147 GFEC--ACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAM 2204
Query: 986 CAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCR 1043
C + +C G C + G C C PG M P L G DN
Sbjct: 2205 CRDVDECADGQQDCHA-----RGMECKNLIGTFACVCPPG-MRP--LPGSGEGCTDDNEC 2256
Query: 1044 HS--CLCQNGGTCDPV-SGHCACPEGWAGLACEKECLPRDVRAG----------CRHSGG 1090
H+ LC NG + S C C EG+ EC D+R G CR
Sbjct: 2257 HAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTEC--HDIRQGPCFAEVLQTMCR---- 2310
Query: 1091 CLNGGLCDPHTGRCLCPA--GWTGDKCQSPCLRGWFGEACAQRCSCPPGAA--------- 1139
L+ C C GW G +C+ L G A R CP G+
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPG----TSAYRKLCPHGSGYTAEGRDVD 2365
Query: 1140 --------CHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPAC------H 1185
C H G C G C+ P + C M +C C
Sbjct: 2366 ECRMLAHLCAH--GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNT 2423
Query: 1186 PATGTCSCAAGY----HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
+ CSC GY G +C+ C+ LC G CRCP GF
Sbjct: 2424 KGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAF------TCRCPPGF- 2476
Query: 1242 GTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVG 1300
T + C C+ G CG C G+ C C +G G G
Sbjct: 2477 -TQHHQACFD---NDECSAQPGPCGAHGHCHNTPGSFRC-------ECHQGFTLVSSGHG 2525
Query: 1301 CEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPAT 1360
CE C H C LG G C +CP G + +C N P T
Sbjct: 2526 CEDVNECDGP---HRCQHGCQNQLG--GYRC--SCPQGFTQHSQWAQCVDENECALSPPT 2578
Query: 1361 -GTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC--LCPAGFHGHFC 1417
G+ C G C CP GF Q L CQ C G C C G C
Sbjct: 2579 CGSASCRNTLGGFRC--VCPSGFDFD--QALGGCQEVDECAGRRGPCSYSCANTPGGFLC 2634
Query: 1418 ERGCEPGSFGEG 1429
GC G F G
Sbjct: 2635 --GCPQGYFRAG 2644
Score = 270 bits (690), Expect = 8e-72
Identities = 411/1591 (25%), Positives = 535/1591 (33%), Gaps = 331/1591 (20%)
Query: 62 CVQALSHTV---PVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQP 118
C + + TV P+ GC C+G R Y + RT C G Q
Sbjct: 137 CQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRT--GPCFG---QV 191
Query: 119 DEEGC----LSAECSASLCFH------GGRCVPGSAQPCHCPPGF----QGPRCQYDVDE 164
EGC C+ +LC G C AQP C GF CQ DVDE
Sbjct: 192 GPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQ-DVDE 250
Query: 165 CRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTC--LAINSC--ALGNGGCQHHCVQ 219
C+ G CQ CVN GS+ C C G RL S C +C L G C
Sbjct: 251 CQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAG 310
Query: 220 LTITRHRCQCR--------------PGFQLQEDGRHCVRRSPCANRN--------GSCMH 257
TR +C C P E + C +R P + G +
Sbjct: 311 -HYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSN 369
Query: 258 RCQVVRGLARCECH-----------VGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQG 305
G AR H G + +D C C +G CL T
Sbjct: 370 GMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPS 429
Query: 306 SFKCVCHAGYELGADGR--------------------------QCY--------RIEMEI 331
S++C C+ GY G +CY R
Sbjct: 430 SYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVD 489
Query: 332 VNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP-CCQQVCTNN 389
V+ C + G C G C +T C C G+EL D + C+D ++CA S C VC N
Sbjct: 490 VDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNE 549
Query: 390 PGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRR 449
G + C C G+ L+ G C D+DEC + HCTN GSF+C C G + D R
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 450 GC--SPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTE 507
C + + + RP P V + E D G E +L E
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPG-TVTKSECCCANPDHGFG---EPCQLCPAKDSAE 665
Query: 508 KFVCLDDSFG--------HDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDT 559
G ++C+L + C NG C+ G +CN
Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANG--------VCENLRGSYRCVCNLGYEAGA 717
Query: 560 FGKNCSFSCSCQ-NGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN--- 615
GK+C+ C N CD+ G C+ PG +C G + C+ C +
Sbjct: 718 SGKDCTDVDECALNSLLCDN--GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPC 775
Query: 616 -RGRCHRLYGA--CLCDPGL----YGRFC----HLTCPPWAFGPGCSEECQCVQPHTQSC 664
G C L G+ C C PG G FC TC W +E +C + + Q
Sbjct: 776 VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTC--WL----KIQESRC-EVNLQGA 828
Query: 665 DKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGK---RCPAG 721
R C+ G C+ CE+ P C + GV CD V+ EC CP G
Sbjct: 829 SLRSECCATLGAAWGSPCE-RCEI---DPACARGFARMTGVTCDDVN-ECESFPGVCPNG 883
Query: 722 FQGEDCGQ---ECPVGTFGVNCSSSC-SCGGAPCHGVTGQCRCP---PGRTGEDCEADCP 774
G ECP G C PC + C PG+ D
Sbjct: 884 RCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSI 943
Query: 775 EGRWGLGCQEICPACQHAARCDPET--GACLCLPGFVGSRCQDVCPAGWYGP---SCQTR 829
WG+ C E CP DPE+ A LC P +G +D + C+
Sbjct: 944 GAVWGVEC-EACP--------DPESLEFASLC-PRGLGFASRDFLSGRPFYKDVNECKVF 993
Query: 830 CSCANDGHCHPATG--HCSCAPGWTGFSCQRAC---DTGHWGPDC-----------SHPC 873
G C G HC+CA G+ + +R C D PD S C
Sbjct: 994 PGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFEC 1053
Query: 874 NCSAGHGSCDAISGLC-----------LCEAG---YVGPRCEQQCPQGH----FGPGCE- 914
C G+ S + C LC G + QCP GH G CE
Sbjct: 1054 ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACED 1113
Query: 915 -QRCQ-----CQHGAACDHVSGA--CTCPAGWRGTFCEHAC----PAGFFGLDCRSACNC 962
C C HG C +V GA C+C AG++ T C C C
Sbjct: 1114 IDECSLSDGLCPHG-QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCIN 1172
Query: 963 TAGA-ACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCA 1021
T G+ C G L P GR CA+ C Q C N P +C C
Sbjct: 1173 TEGSYRCSCGQGYSLMPDGR---ACADVDECEENPRVCDQG-HCTN----MPGGHRCLCY 1224
Query: 1022 PGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDV 1081
G+M ++ C D H CL G C+ G C C+ + R
Sbjct: 1225 DGFMATPDMRTCVDVDECDLNPHICL---HGDCENTKGSFVC-------HCQLGYMVRKG 1274
Query: 1082 RAGCRHSGGCLNGG-LCDPHTG--------RCLCPAGWTGDKCQSPCLRGWFGEACAQRC 1132
GC C GG CD H C C GW GD + L E +Q
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL----DECVSQEH 1330
Query: 1133 SCPPGAACHHVTGA--CRCPPGFTGSG--CEQACPPGSFGEDCAQ---MCQCPGENPACH 1185
C P C +V G+ C C GF G G CE ++CA+ +C
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDR-------DECAENVDLCD--------- 1374
Query: 1186 PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC 1245
G C A G + C+ P C+ + C G C A G+C G C
Sbjct: 1375 --NGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC--AFGSCENLPGMFRCIC 1430
Query: 1246 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC 1305
N R G NCT + C C + G C+ PG C + N GVGC T
Sbjct: 1431 NGGYELDRGGGNCTDINECADPVNC--INGVCINTPGSYLCSCPQDFELNPSGVGCVDTR 1488
Query: 1306 SCR----------NGGLCHASNG------SCSCGLG--WTGRHCELA-----------CP 1336
+ +G C A G SC C LG W G CEL CP
Sbjct: 1489 AGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAW-GNPCELCPMANTTEYRTLCP 1547
Query: 1337 PGRYGAACHLECSCHNNSTCEPATGTCR---CGPGFYGQACEHPCPPGFHGAG----CQG 1389
G + + C+ G C+ C F CE CPPG+H + C+
Sbjct: 1548 GGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE--CPPGYHLSEHTRICED 1605
Query: 1390 LCWCQ-HGAPCDP-------ISGRCLCPAGF 1412
+ C H C P + C+CPA +
Sbjct: 1606 IDECSTHSGICGPGTCYNTLGNYTCVCPAEY 1636
Score = 265 bits (678), Expect = 2e-70
Identities = 405/1660 (24%), Positives = 542/1660 (32%), Gaps = 442/1660 (26%)
Query: 101 TTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQ----GP 156
TT+ R + C D E C + C + GS + C C G++ G
Sbjct: 677 TTDGRDINECAL------DPEVCANGVCEN---------LRGSYR-CVCNLGYEAGASGK 720
Query: 157 RCQYDVDECRTHNGGCQHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH 215
C DVDEC ++ C + C N+PGSY C C PGF D+ C ++ C + C
Sbjct: 721 DCT-DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECL--SSPCVS 777
Query: 216 HCVQLTITRHRCQCRPGFQLQEDGRHC-----------VRRSPC-ANRNGSCMH-RCQVV 262
+ + C+C PG +L G C ++ S C N G+ + C
Sbjct: 778 GVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCAT 837
Query: 263 RGLA------RCE----CHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVC 311
G A RCE C G+ G C+DV+EC + C +G C+NT GSF+C C
Sbjct: 838 LGAAWGSPCERCEIDPACARGFARMT-GVTCDDVNECESFPGVCPNGRCVNTAGSFRCEC 896
Query: 312 HAGYELGADGRQCYRIEMEIV------NSCEANNGG--------CSHGCSHTSAGPLC-- 355
G L A GR C + +E + C G CS G C
Sbjct: 897 PEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPD 956
Query: 356 --------TCPRGY-----ELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAG 400
CPRG + + + DV++C P C C N G + C C G
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1016
Query: 401 YRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQCSC----EAGYRLHEDRRGCSPLE 455
+ L A C D+DEC S C + C N GSF+C C E+G+ L + C ++
Sbjct: 1017 FALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFML---MKNCMDVD 1073
Query: 456 EPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADE--EEAELRGEHTLTEKFVCLD 513
E D P L + + + + H LT K +
Sbjct: 1074 ECARD---------------------PLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE 1112
Query: 514 DSFGHDCSLTCDDCRNGGTC-LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQN 572
D +CSL+ C +G ++G C C G+ PD G C QN
Sbjct: 1113 DI--DECSLSDGLCPHGQCVNVIGAFQCSCHAGFQS-------TPDRQGCVDINECRVQN 1163
Query: 573 GGT---CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA--CL 627
GG C + G+ RC G + DG + C + ++G C + G CL
Sbjct: 1164 GGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDE-CEENPRVCDQGHCTNMPGGHRCL 1222
Query: 628 CDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHT---QSCDKRDGSCSCKAGFRGERCQA 684
C G TC +EC + PH C+ GS C
Sbjct: 1223 CYDGFMATPDMRTCVD-------VDECD-LNPHICLHGDCENTKGSFVC----------- 1263
Query: 685 ECELGYF----GPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNC 740
C+LGY GC C VG G NC
Sbjct: 1264 HCQLGYMVRKGATGCSDVDECEVG--------------------------------GHNC 1291
Query: 741 SSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETG 800
S SC P + CRC PG G+ G C ++ RC P G
Sbjct: 1292 DSHASCLNIP---GSFSCRCLPGWVGD-----------GFECHDLDECVSQEHRCSPR-G 1336
Query: 801 ACLCLPGFVGSRCQDVCPAGWYGPS--CQTRCSCA-NDGHCHPATGHCSCAPGWTGFSCQ 857
CL +PG RC C G+ G C+ R CA N C G C APG C+
Sbjct: 1337 DCLNVPG--SYRC--TCRQGFAGDGFFCEDRDECAENVDLCD--NGQCLNAPGGYRCECE 1390
Query: 858 RACDTGHWGPDCSHPCNCSAGH----GSCDAISGL--CLCEAGYVGPRCEQQCPQGHFGP 911
D C C+ G+ GSC+ + G+ C+C GY R C +
Sbjct: 1391 MGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDIN--- 1447
Query: 912 GCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCR------------ 957
C C +G C + G+ C+CP + P+G +D R
Sbjct: 1448 ECADPVNCING-VCINTPGSYLCSCPQDF------ELNPSGVGCVDTRAGNCFLETHDRG 1500
Query: 958 -SACNCTAGAACDAVNGSCLCPAGRRGPRCAETCP-AHTYGH------------------ 997
S +C+A SC C GR E CP A+T +
Sbjct: 1501 DSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVI 1560
Query: 998 -----NCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNC-RHSCLCQ 1049
C + G C G QC C PG+ + C D C HS +C
Sbjct: 1561 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICED---IDECSTHSGIC- 1616
Query: 1050 NGGTCDPVSGH--CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCP 1107
GTC G+ C CP + + C+ RH G L T + C
Sbjct: 1617 GPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCC 1676
Query: 1108 AGWTGDKCQSPCLRGWFGEACAQRCS---------------------------------- 1133
+ G PC EAC S
Sbjct: 1677 SYNIGQAWNRPC------EACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPA 1730
Query: 1134 -CPPGAACHHV-TGACRCPPGFTGS----GCEQACPPGSFGEDCAQMCQCPGENPACHPA 1187
C G + + + C CP GF + CE GS C Q C P
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN-----IPG 1785
Query: 1188 TGTCSCAAGYH---GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLG 1242
+ C C GY G +C R C ++ + G C G+ C C GF
Sbjct: 1786 SYRCKCTRGYKLSPGGACVGR-------NECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 1243 T----------DC------NLTCPQGRFGPNC--------THVCGCGQGAACDPVTGT-- 1276
+ +C N TC NC TH C C + G
Sbjct: 1839 SADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC 1898
Query: 1277 ----CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN------GGLCHASNGSCSCGLGW 1326
CL G C+ G G C T C + G C GS C
Sbjct: 1899 RFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC---- 1954
Query: 1327 TGRHCELACPPGRYGAACHL----ECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGF 1382
CPPG + H ECS N GTC PG + + CPPGF
Sbjct: 1955 -------ICPPGFQVQSDHCIDIDECSEEPNLC---LFGTCTNSPGSF----QCLCPPGF 2000
Query: 1383 ----HGAGC----QGLCW-------CQHGAPCDPISGRCLC---PAGFHGHFCERGCEPG 1424
+G C Q C+ C + RC C P G CE + G
Sbjct: 2001 VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEG 2060
Query: 1425 S--------FGEGCHQRCD---------------CDGGAPCDPVTG--LCLCPPGRSGAT 1459
S FG G D C G C G C CP G S
Sbjct: 2061 SAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRCECPFGYSLDF 2119
Query: 1460 CNLDCRRGQFGPSCTLHCDCGGGADCDPVSG-QCHCVDGY 1498
++C C++ CG G + + G +C C DG+
Sbjct: 2120 TGINCVDTD---ECSVGHPCGQGTCTNVIGGFECACADGF 2156
Score = 177 bits (448), Expect = 9e-44
Identities = 101/286 (35%), Positives = 128/286 (44%), Gaps = 18/286 (6%)
Query: 130 ASLCFHGGRCVPGSAQPCHCPPGFQGPRCQ---YDVDECRTHNGGCQHRCVNTPGSYLCE 186
A LC HG + CHC G+ D+DEC C C NT GS+LC
Sbjct: 2371 AHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCS 2430
Query: 187 CKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRS 246
C G+ L D RTC ++ C CQ CV T+ C+C PGF C
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVN-TVGAFTCRCPPGFTQHHQA--CFDND 2487
Query: 247 PCANRNGSC--MHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQ 304
C+ + G C C G RCECH G+ L + G CEDV+EC G +C HGC N
Sbjct: 2488 ECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHGCQNQL 2546
Query: 305 GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC-SHGCSHTSAGPLCTCPRGYEL 363
G ++C C G+ + QC N C + C S C +T G C CP G++
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVD-----ENECALSPPTCGSASCRNTLGGFRCVCPSGFDF 2601
Query: 364 DTDQRTCIDVDDCAD--SPCCQQVCTNNPGGYECGCYAGYRLSADG 407
D C +VD+CA PC C N PGG+ CGC GY + G
Sbjct: 2602 DQALGGCQEVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQG 2646
Score = 161 bits (408), Expect = 4e-39
Identities = 366/1497 (24%), Positives = 473/1497 (31%), Gaps = 359/1497 (23%)
Query: 187 CKPGFRLHTDSRTCLA-INSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRR 245
C PG+R C+ I A G G C + C C G G
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEGFCSQP--------NLCTCADGTLAPSCG------ 113
Query: 246 SPCANRNGSCMHRCQ---VVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLN 302
+R C C RG A C C GY G C G C GC N
Sbjct: 114 ---VSRGSGCSVSCMNGGTCRG-ASCLCQKGYT----GTVC--------GQPICDRGCHN 157
Query: 303 TQ---GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC-----SHGCSHTSAGPL 354
G +C C G+ G QC R + G C GC H G +
Sbjct: 158 GGRCIGPNRCACVYGFM----GPQCER---------DYRTGPCFGQVGPEGCQHQLTGLV 204
Query: 355 CT-------------------------CPRGYELDTDQRTCIDVDDCADSP--CCQQVCT 387
CT C RG+ + C DVD+C P C C
Sbjct: 205 CTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCV 264
Query: 388 NNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCT-NLAGSF---QCSCEAGYR 443
N G + C C G+RLS CED A C +LAG + QC C+ G
Sbjct: 265 NMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRC 324
Query: 444 LHEDRRGCSPLEE---PMVDLDGELPFVRPLPHIAVLQDELPQL--FQDDDVGADEEEAE 498
P+ E P + + + LP + P L F + +G A
Sbjct: 325 W-----AAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPAR 379
Query: 499 LRGEHTLTEKFVCLDDSFGH----DCSLTCDDCRN------GGTCLLGLDG--CDCPEGW 546
L + L + + T D CR+ G CL C+C G+
Sbjct: 380 LNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGY 439
Query: 547 TGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYG 604
T + E D C+ S C +G C ++ G CRC PG T C
Sbjct: 440 TQDVRGECIDVD----ECT-SSPCHHGD-CVNIPGTYHCRCYPGFQATPTRQACVDV--- 490
Query: 605 KHCRKKCNCANRGRCHRLYGA--CLCDPGLY----GRFCHLTCPPWAFGPGCSEECQCVQ 658
C + GRC G+ C+C+ G G+ C C+ CV
Sbjct: 491 DECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-------VDHNECATSTMCVN 543
Query: 659 PHTQSCDKRDGS--CSCKAGFR----GERCQA--ECELGYFGPG------CWQA-----C 699
C DGS C CK GF G C EC+ PG C C
Sbjct: 544 G---VCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT----PGICVNGHCTNTEGSFRC 596
Query: 700 TCPVGVACDSVSGEC-----GKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGV 754
C G+A + C C + C + P G S C C P HG
Sbjct: 597 QCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFP----GTVTKSECCCAN-PDHGF 651
Query: 755 TGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPET---GACLCLPGFVGS 811
C+ P + + +A C G LG A DPE G C L G
Sbjct: 652 GEPCQLCPAKDSAEFQALCSSG---LGITTDGRDINECA-LDPEVCANGVCENLRGSYRC 707
Query: 812 RCQDVCPAGWYGPSCQTRCSCA------NDGHCH--PATGHCSCAPGWTGFSCQRACDTG 863
C AG G C CA ++G C P + CSC PG+ + C
Sbjct: 708 VCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDV 767
Query: 864 HWGPDC-SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHG 922
+C S PC +SG+C AG +C GPG R
Sbjct: 768 D---ECLSSPC-----------VSGVCRNLAGSYTCKC---------GPG--SRLDPSGT 802
Query: 923 AACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRR 982
D G C W E C G RS C T GAA G
Sbjct: 803 FCLDSTKGTC-----WL-KIQESRCEVNLQGASLRSECCATLGAAW-----------GSP 845
Query: 983 GPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNC 1042
RC E PA C++ A G +CD V+ +C PG CP G
Sbjct: 846 CERC-EIDPA------CARGFARMTGVTCDDVN-ECESFPG--------VCPNG------ 883
Query: 1043 RHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG 1102
C+ G S C CPEG A + C+ DVR +P
Sbjct: 884 --RCVNTAG------SFRCECPEGLMLDASGRLCV--DVRL--------------EP--- 916
Query: 1103 RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACH------HVTGACRCPPGFTGS 1156
C W D+C + + C G C + A CP G G
Sbjct: 917 ---CFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGL-GF 972
Query: 1157 GCEQACPPGSFGEDCAQMCQCPG--ENPACHPATGT--CSCAAGYHGPSCQQRCPPGRYG 1212
F +D + PG + C G+ C+CA G+ + ++ C
Sbjct: 973 ASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDEC 1032
Query: 1213 PGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDP 1272
LCG G+C G+ C F G + + NC V C + DP
Sbjct: 1033 RISPDLCG---QGTCVNTPGSFECEC-FPGYESGFMLMK-----NCMDVDECAR----DP 1079
Query: 1273 VT---GTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR-NGGLCHASNGSCSCGLG--W 1326
+ GTC G +C G G CE C + GLC +G C +G
Sbjct: 1080 LLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLC--PHGQCVNVIGAFQ 1137
Query: 1327 TGRHCELACPPGRYGAACHLECSCHNNST---CEPATGT--CRCGPGFY----GQACEHP 1377
H P R G EC N C G+ C CG G+ G+AC
Sbjct: 1138 CSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADV 1197
Query: 1378 CPPGFHGAGC-QGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDC 1436
+ C QG C G RCLC GF R C D
Sbjct: 1198 DECEENPRVCDQGHCTNMPGGH------RCLCYDGFMATPDMRTC------------VDV 1239
Query: 1437 DGGAPCDPVTGLCL---CPPGRSGATCNLDC----RRGQFGPSCTLHCDCGGGADCD--- 1486
D CD +CL C + C+ R+G G S C+ GG +CD
Sbjct: 1240 D---ECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGH-NCDSHA 1295
Query: 1487 -----PVSGQCHCVDGYMGP--TCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSG 1536
P S C C+ G++G C + E+ +G +P S R T R G
Sbjct: 1296 SCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQG 1352
Score = 125 bits (315), Expect = 2e-28
Identities = 78/226 (34%), Positives = 100/226 (44%), Gaps = 8/226 (3%)
Query: 102 TEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCVPG-SAQPCHCPPGF-QGPRC 158
T+ + C RG++ + D C EC++ CV A C CPPGF Q +
Sbjct: 2423 TKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA 2482
Query: 159 QYDVDECRTHNGGC--QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHH 216
+D DEC G C C NTPGS+ CEC GF L + C +N C G CQH
Sbjct: 2483 CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG 2541
Query: 217 CVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSC-MHRCQVVRGLARCECHVGYQ 275
C Q + +RC C GF CV + CA +C C+ G RC C G+
Sbjct: 2542 C-QNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600
Query: 276 LAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADG 321
C++VDECA C++ C NT G F C C GY G
Sbjct: 2601 FDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG 2646
Score = 122 bits (305), Expect = 3e-27
Identities = 199/764 (26%), Positives = 237/764 (31%), Gaps = 182/764 (23%)
Query: 844 HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQ 903
H C PGW F + C P C C G G C LC C G + P C
Sbjct: 65 HAYCCPGWRTFPGRSQCVV----PICRRAC----GEGFCSQ-PNLCTCADGTLAPSCGVS 115
Query: 904 CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFC-EHACPAGFFGLDCRSACNC 962
G GC C +G C S C C G+ GT C + C G C
Sbjct: 116 -----RGSGCS--VSCMNGGTCRGAS--CLCQKGYTGTVCGQPICDRG-----------C 155
Query: 963 TAGAACDAVNGSCLCPAGRRGPRC--------------AETCPAHTYGHNCSQACACFN- 1007
G C N C C G GP+C E C G C++A C
Sbjct: 156 HNGGRCIGPN-RCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATV 214
Query: 1008 ----GASCDPVHGQCH-CAPGWMGPSCLQACPAGLYGDNCRH-SCLCQNGGTCDPVSG-- 1059
G C+ Q H C G++ AC D C+ LCQ GG+C + G
Sbjct: 215 GRAWGLPCELCPAQPHPCRRGFIPNIHTGACQD---VDECQAVPGLCQ-GGSCVNMVGSF 270
Query: 1060 HCACPEGW----AGLACEKECLPRDVRAGCRHS---GGCLNGGLCDPHTGR-CLCPAG-- 1109
HC CP G + ACE D RAG S GG G L +T R C C G
Sbjct: 271 HCRCPVGHRLSDSSAACE------DYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRC 324
Query: 1110 WTGDKCQSPC-LRG--WFGEACAQRCSCPPG-------------AACHHVTGACRCPPGF 1153
W C RG F + CAQR PG G R P
Sbjct: 325 WAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHG 384
Query: 1154 TGSGCEQACPPGSFGEDCAQMCQ-----------CPGENPACHPATGTCSCAAGY----- 1197
+ + + PG+ A + Q C P++ C C GY
Sbjct: 385 SDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVR 444
Query: 1198 --------------HGPSCQQ-------RCPPGRYGPGCEQLC----GCL-NGGSCDAAT 1231
H C RC PG Q C C+ +GG C
Sbjct: 445 GECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCH--L 502
Query: 1232 GACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERG 1291
G C G CN G NC C C V G CL G C+ G
Sbjct: 503 GRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMC--VNGVCLNEDGSFSCLCKPG 560
Query: 1292 CPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH 1351
G C C+ G+C NG C+ G C G G C H
Sbjct: 561 FLLAPGGHYCMDIDECQTPGIC--VNGHCTNTEGSFRCQCLGGLAVGTDGRVC---VDTH 615
Query: 1352 NNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQH-----GAPCDPISGRC 1406
STC YG + C F G + C C + G PC
Sbjct: 616 VRSTC-------------YGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQ------ 656
Query: 1407 LCPAGFHGHF---CERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLD 1463
LCPA F C G + G ++ C D P G+C G CNL
Sbjct: 657 LCPAKDSAEFQALCSSGLGITTDGRDINE-CALD---PEVCANGVCENLRGSYRCVCNLG 712
Query: 1464 CRRGQFGPSCT---------LHCDCGGGADCDPVSGQCHCVDGY 1498
G G CT L CD G P S C C G+
Sbjct: 713 YEAGASGKDCTDVDECALNSLLCD-NGWCQNSPGSYSCSCPPGF 755
Score = 89.7 bits (221), Expect = 2e-17
Identities = 66/194 (34%), Positives = 80/194 (41%), Gaps = 21/194 (10%)
Query: 109 RCCRGWMQQPDEEGCL-SAECSASL--CFHGGRC--VPGSAQPCHCPPGF----QGPRCQ 159
RC G+ Q + C + ECSA C G C PGS + C C GF G C+
Sbjct: 2471 RCPPGFTQH--HQACFDNDECSAQPGPCGAHGHCHNTPGSFR-CECHQGFTLVSSGHGCE 2527
Query: 160 YDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 219
DV+EC + CQH C N G Y C C GF H+ C+ N CAL C +
Sbjct: 2528 -DVNECDGPHR-CQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCR 2585
Query: 220 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 279
T+ RC C GF + C CA R G C + C G C C GY A
Sbjct: 2586 NTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQ 2645
Query: 280 GKACEDVDECAAGL 293
G C +GL
Sbjct: 2646 G-------HCVSGL 2652
Score = 41.2 bits (95), Expect = 0.008
Identities = 53/187 (28%), Positives = 65/187 (34%), Gaps = 33/187 (17%)
Query: 1324 LGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFH 1383
L W+ C +A GR+ A LE + + G + GP G C PG+
Sbjct: 18 LAWSALLC-MAGGQGRWDGA--LEAAGPGRVRRRGSPGILQ-GPNVCGSRFHAYCCPGWR 73
Query: 1384 GAGCQGLCW-------CQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDC 1436
+ C C G P C C G C S G GC C
Sbjct: 74 TFPGRSQCVVPICRRACGEGFCSQP--NLCTCADGTLAPSCGV-----SRGSGCS--VSC 124
Query: 1437 DGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVD 1496
G C + CLC G +G C GQ P C C GG P +C CV
Sbjct: 125 MNGGTCRGAS--CLCQKGYTGTVC------GQ--PICDRGCH-NGGRCIGP--NRCACVY 171
Query: 1497 GYMGPTC 1503
G+MGP C
Sbjct: 172 GFMGPQC 178
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 304 bits (779), Expect = 4e-82
Identities = 374/1457 (25%), Positives = 538/1457 (36%), Gaps = 272/1457 (18%)
Query: 161 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 219
D++EC+ G C + +C NT GS+ C C GF L + R C I+ C + C
Sbjct: 1073 DINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1132
Query: 220 LTITRHRCQCRPGFQLQEDG----RHCV-----RRSPCANRNGSCMHRCQVVRGLARCEC 270
T C+C G+ E G ++C+ R+P R G+C++ G +C+C
Sbjct: 1133 NTPGSFECECFEGY---ESGFMMMKNCMDIDECERNPLLCRGGTCVN----TEGSFQCDC 1185
Query: 271 HVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEM 329
+G++L+ + C D++EC+ C +G C+N G+++C C+ GY+ D + C I+
Sbjct: 1186 PLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDID- 1244
Query: 330 EIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCT 387
C NGGC C+++ C+C GY L D R+C D+D+C ++P C CT
Sbjct: 1245 ----ECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCT 1300
Query: 388 NNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHE 446
N PG Y C CY G+ S D C DV+EC + C C N GSF C C+ GY + +
Sbjct: 1301 NIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKK 1360
Query: 447 DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLT 506
GC+ ++E E+ H + L +P F + R E +
Sbjct: 1361 GTTGCTDVDE------CEIGAHNCDMHASCL--NIPGSF----------KCSCR-EGWIG 1401
Query: 507 EKFVCLDDSFGHDCSLTCDDCRNGGTCL--LGLDGCDCPEGWT--GLICNETCPPDTFGK 562
C+D +CS C C+ G C C EG+T G C++ D +
Sbjct: 1402 NGIKCIDLD---ECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDV---DECAE 1455
Query: 563 NCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 622
N + C+N G C +V GA RC CE G + C+ C+ + C +
Sbjct: 1456 NINL---CEN-GQCLNVPGAYRC-------ECEMGFTPASDSRSCQDIDECSFQNIC--V 1502
Query: 623 YGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERC 682
+G C PG++ C G C++ +C P + +G C G C
Sbjct: 1503 FGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADP----INCVNGLCVNTPGRYECNC 1558
Query: 683 QAECELGYFGPGCWQACTCPVGVACDSVSGECG-KRCPAGFQGEDCGQECPVGTFGVNCS 741
+ +L G GC D+ G C K P G C E VG +C
Sbjct: 1559 PPDFQLNPTGVGC-----------VDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSC- 1606
Query: 742 SSCSCG---GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 798
CS G G PC CPP + E CP G G I + C
Sbjct: 1607 -CCSLGKAWGNPCE------TCPPVNSTEYYTL-CPGGE-GFRPNPITIILEDIDECQEL 1657
Query: 799 TGACL---CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFS 855
G C C+ F +C+ CP G+Y C ++ HP C PG +
Sbjct: 1658 PGLCQGGNCINTFGSFQCE--CPQGYYLSEDTRICEDIDECFAHPGV----CGPG----T 1707
Query: 856 CQRACDTGHWGPDC-SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE 914
C G++ C + GH D C Y G CE + P +
Sbjct: 1708 CYNT--LGNYTCICPPEYMQVNGGHNCMDMRKSFCY--RSYNGTTCENELPFN----VTK 1759
Query: 915 QRCQCQH--GAACDHVSGACTCP--AGWRGTFCEHACPAGFFGL---------DCRSACN 961
+ C C + G A + C P A ++ T C + P F + +C+
Sbjct: 1760 RMCCCTYNVGKAWNKPCEPCPTPGTADFK-TICGN-IPGFTFDIHTGKAVDIDECKEIPG 1817
Query: 962 CTAGAACDAVNGS--CLCPAGRRGPR----CAETCPAHTYGHNCSQACACFNGASCDPVH 1015
A C GS C CP G C + + C + C N P
Sbjct: 1818 ICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCIN----SPGS 1873
Query: 1016 GQCHCAPGW-MGPS--------CLQ---ACPAGLYGD-NCRHSCLCQNG----------- 1051
+C CA G+ + P+ CL+ C GL D + C+C NG
Sbjct: 1874 YRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCM 1933
Query: 1052 ------------GTCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLC 1097
GTC G +C C G+ L +CL D+ G G C
Sbjct: 1934 DVDECERHPCGNGTCKNTVGSYNCLCYPGFE-LTHNNDCL--DIDECSSFFGQVCRNGRC 1990
Query: 1098 DPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTG 1155
G +CLC G+ C+ E A SC PG C ++ G+ RC
Sbjct: 1991 FNEIGSFKCLCNEGYELTPDGKNCID--TNECVALPGSCSPG-TCQNLEGSFRC------ 2041
Query: 1156 SGCEQACPPG--SFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGP 1213
CPPG E+C + +C + C G+C+ G Q CPPG
Sbjct: 2042 -----ICPPGYEVKSENCIDINECDEDPNIC--LFGSCTNTPG----GFQCLCPPGFVLS 2090
Query: 1214 GCEQLCGCLNGGSC--DAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC- 1270
+ C C + G C P F T C+ + G G G C
Sbjct: 2091 DNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCC---------CSKMPGEGWGDPCE 2141
Query: 1271 -----DPVTGTCLCPPGRAGVRCERGCPQNRFGVG-CEHTCSCRNGGLCHASNGS--CSC 1322
D V LCP G V R V C + + G C ++GS C C
Sbjct: 2142 LCPKDDEVAFQDLCPYGHGTV---PSLHDTREDVNECLESPGICSNGQCINTDGSFRCEC 2198
Query: 1323 GLGWTGRHCELACPPGRYGAACHLECSCHN---NSTCEPATGT--CRCGPGFYG---QAC 1374
+G+ + + C ECS N N TC G+ C C GF C
Sbjct: 2199 PMGYNLDYTGVRCVDTD-------ECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNC 2251
Query: 1375 EHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEP-GSFGEGCHQR 1433
E + C C G S C CP G+ ++ C+ EG H
Sbjct: 2252 EDINECAQNPLLCAFRCMNTFG------SYECTCPIGYALREDQKMCKDLDECAEGLH-- 2303
Query: 1434 CDCDG-GAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGAD-CDPVS 1489
DC+ G C + G +C+CPPG + R G C +C C+ +
Sbjct: 2304 -DCESRGMMCKNLIGTFMCICPPGMA---------RRPDGEGCVDENECRTKPGICE--N 2351
Query: 1490 GQCHCVDGYMGPTCREG 1506
G+C + G C EG
Sbjct: 2352 GRCVNIIGSYRCECNEG 2368
Score = 296 bits (757), Expect = 1e-79
Identities = 380/1505 (25%), Positives = 533/1505 (35%), Gaps = 298/1505 (19%)
Query: 130 ASLCFHGGRCVPG-SAQPCHCPPGFQGPR---CQYDVDECRTHNGGCQHRCVNTPGSYLC 185
A+LC +G RC+P S+ C C G++ C DVDEC T N CVNTPGSY C
Sbjct: 502 ANLCLNG-RCIPTVSSYRCECNMGYKQDANGDC-IDVDEC-TSNPCTNGDCVNTPGSYYC 558
Query: 186 ECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRR 245
+C GF+ + C+ I+ C C++ T +C C GF+L DG++CV
Sbjct: 559 KCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDH 618
Query: 246 SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-AAGLAQCAHGCLNTQ 304
C N C G +C C G+ LA +G+ C DVDEC G+ H C+N++
Sbjct: 619 DECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGH-CINSE 677
Query: 305 GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-----------CSHTSAG- 352
GSF+C C G +G DGR C M G C C++ G
Sbjct: 678 GSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF 737
Query: 353 --PLCTCP------------RGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECG 396
P CP G + D R D+++CA P C +C N G Y C
Sbjct: 738 GEPCQPCPAKNSAEFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRGSYRCN 794
Query: 397 CYAGYRLSADGCGCEDVDECASSRGGCEHH-CTNLAGSFQCSCEAGYRLHEDRRGCSPLE 455
C +GY A G C D+DEC +R C++ C N GS+ C+C GY + C +
Sbjct: 795 CNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDIN 854
Query: 456 EPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDS 515
E + P V +++G+ E G + +C+D
Sbjct: 855 ECESN-----PCVNGACR--------------NNLGSFNCECS-PGSKLSSTGLICIDSL 894
Query: 516 FGHDCSLTCDDCR-----NGGTCLLGLDGCDCPEGWTGLICNETCPPDTF---GKNCSFS 567
G C L D R NG T L + C G C E C DT G
Sbjct: 895 KG-TCWLNIQDSRCEVNINGAT--LKSECCATLGAAWGSPC-ERCELDTACPRGLARIKG 950
Query: 568 CSCQNGGTCDSVTGAC---RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYG 624
+C++ C+ G C RC +CE CP+G + C +C+ +
Sbjct: 951 VTCEDVNECEVFPGVCPNGRCVNSKGSFHCE--CPEGLTLDGTGRVCLDIRMEQCYLKWD 1008
Query: 625 ACLCDPGLYGRFCHLTCPPWAFGPGCSEEC-QCVQPHTQS----CDKRDGSCS------- 672
C + G+F C A G EC +C +P T+ C + G +
Sbjct: 1009 EDECIHPVPGKFRMDAC-CCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTG 1067
Query: 673 ---------CKAGFRGERCQAECE--LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAG 721
CKA F G +C +G F C C G A D C
Sbjct: 1068 RPFYKDINECKA-FPGMCTYGKCRNTIGSF------KCRCNSGFALDMEERNCTDIDECR 1120
Query: 722 FQGEDCGQECPVGTFG-----------------VNCS--SSCS-----CGGAPCHGVTG- 756
+ CG V T G NC C C G C G
Sbjct: 1121 ISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGS 1180
Query: 757 -QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGS-- 811
QC CP G DC + +C +C G C C PG+ +
Sbjct: 1181 FQCDCPLGHELSPSREDCVDINECSLSDNLC----RNGKCVNMIGTYQCSCNPGYQATPD 1236
Query: 812 --RCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDC 869
C D+ C T+C+ + + CSC+ G+ R+C +C
Sbjct: 1237 RQGCTDIDECMIMNGGCDTQCTNSEGSY------ECSCSEGYALMPDGRSCAD---IDEC 1287
Query: 870 -SHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACD 926
++P C G C I G CLC G++ + C + C+ C+
Sbjct: 1288 ENNPDICDG--GQCTNIPGEYRCLCYDGFMASMDMKTCIDVN---ECDLNSNICMFGECE 1342
Query: 927 HVSGA--CTCPAGW---RGTFCEHACPAGFFGLD-CR-SACNCTAGAACDAVNGS--CLC 977
+ G+ C C G+ +GT G +D C A NC A+C + GS C C
Sbjct: 1343 NTKGSFICHCQLGYSVKKGT-------TGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1395
Query: 978 PAG--RRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGP--SCLQAC 1033
G G +C + H CS C N P +C C+ G+ G +C
Sbjct: 1396 REGWIGNGIKCIDLDECSNGTHQCSINAQCVN----TPGSYRCACSEGFTGDGFTCSDV- 1450
Query: 1034 PAGLYGDNCRHSC-LCQNGGTCD-PVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGC 1091
D C + LC+NG + P + C C G+ + + C D C C
Sbjct: 1451 ------DECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDID---ECSFQNIC 1501
Query: 1092 LNGGLCD--PHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTG--AC 1147
+ G C+ P C+C G+ D+ C + CA +C G C + G C
Sbjct: 1502 V-FGTCNNLPGMFHCICDDGYELDRTGGNCTD---IDECADPINCVNG-LCVNTPGRYEC 1556
Query: 1148 RCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATG------TCSCAAGYHGPS 1201
CPP F + C G + + +C+ G +C C+ G +
Sbjct: 1557 NCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGN 1616
Query: 1202 CQQRCPPGR------YGPG------------------CEQLCGCLNGGSCDAATGA--CR 1235
+ CPP PG C++L G GG+C G+ C
Sbjct: 1617 PCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCE 1676
Query: 1236 CPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG-TCLCPPGRAGVRCERGCPQ 1294
CP G+ ++ C H CG G + + TC+CPP
Sbjct: 1677 CPQGYYLSEDTRICED--IDECFAHPGVCGPGTCYNTLGNYTCICPP------------- 1721
Query: 1295 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHN-- 1352
V H C C+ S + G CE P + + C +N
Sbjct: 1722 EYMQVNGGHNCMDMRKSFCYRS---------YNGTTCENELP---FNVTKRMCCCTYNVG 1769
Query: 1353 ---NSTCE--PATGTCR----CG--PGF-----YGQACEHPCPPGFHGAGCQGLCWCQHG 1396
N CE P GT CG PGF G+A + G G+C Q G
Sbjct: 1770 KAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIG 1829
Query: 1397 APCDPISGRCLCPAGFHGH----FCERGCEPGSFGEGCHQRCDC---DGGAPCDPVTGLC 1449
S RC CP GF + CE E + C + DC G C+ G
Sbjct: 1830 ------SFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFK 1883
Query: 1450 LCPPG 1454
L P G
Sbjct: 1884 LSPNG 1888
Score = 295 bits (754), Expect = 3e-79
Identities = 397/1616 (24%), Positives = 541/1616 (33%), Gaps = 330/1616 (20%)
Query: 109 RCCRGWMQQPDEEGCLSA-EC--SASLCFHGGRCV--PGSAQPCHCPPGFQG-----PRC 158
RC G+ +E C EC S LC G CV PGS + C C G++ C
Sbjct: 1099 RCNSGFALDMEERNCTDIDECRISPDLC-GSGICVNTPGSFE-CECFEGYESGFMMMKNC 1156
Query: 159 QYDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH-H 216
D+DEC + C+ CVNT GS+ C+C G L C+ IN C+L + C++
Sbjct: 1157 M-DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGK 1215
Query: 217 CVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQL 276
CV + I ++C C PG+Q D + C C NG C +C G C C GY L
Sbjct: 1216 CVNM-IGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYAL 1274
Query: 277 AADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSC 335
DG++C D+DEC C G C N G ++C+C+ G+ D + C VN C
Sbjct: 1275 MPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID-----VNEC 1329
Query: 336 EANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC--------ADSPC----- 381
+ N+ C G C +T +C C GY + C DVD+C + C
Sbjct: 1330 DLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 1389
Query: 382 -----CQQ--------------------------VCTNNPGGYECGCYAGYRLSADGCGC 410
C++ C N PG Y C C G+ + DG C
Sbjct: 1390 SFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTC 1447
Query: 411 EDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVR 469
DVDECA + CE+ C N+ G+++C CE G+ D R C ++E
Sbjct: 1448 SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCN 1507
Query: 470 PLPHI--AVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCS------ 521
LP + + D ++ D G + + + + +C++ ++C+
Sbjct: 1508 NLPGMFHCICDDG----YELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQ 1563
Query: 522 -----LTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC 576
+ C D R G C L P G L CN +C S G C
Sbjct: 1564 LNPTGVGCVDNR-VGNCYLKFG----PRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPC 1618
Query: 577 DSVTGACRCPPGVSGTNCEDGCPKGYYGK------------HCRKKCNCANRGRCHRLYG 624
++ CPP V+ T CP G + C++ G C +G
Sbjct: 1619 ET------CPP-VNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFG 1671
Query: 625 A--CLCDPGLY----GRFC----HLTCPPWAFGPG------------CSEECQCVQPHTQ 662
+ C C G Y R C P GPG C E V
Sbjct: 1672 SFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHN 1731
Query: 663 SCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGF 722
D R C + G C+ E C CT VG A + C A F
Sbjct: 1732 CMDMR--KSFCYRSYNGTTCENELPFNVTKRMC--CCTYNVGKAWNKPCEPCPTPGTADF 1787
Query: 723 QGEDCGQECPVGTFGVNCSSSCS----------CGGAPCHGVTG--QCRCPPGRTGEDCE 770
+ CG P TF ++ + C C G +C CP G + D
Sbjct: 1788 K-TICG-NIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLL 1845
Query: 771 ADCPEGRWGLGCQEICPACQHAARC--DPETGACLCLPGF----------------VGSR 812
C + C CQ A C P + C C GF + +
Sbjct: 1846 LVCEDID---ECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNV 1902
Query: 813 C------------QDVCPAGWYGPSCQTRCSCANDGHCHP-ATGHCSCAPGWTGFSCQRA 859
C Q +C G+ QT C ++ HP G C G C
Sbjct: 1903 CSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPG 1962
Query: 860 CDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQC 919
+ H DC CS+ G +G C E G C + G C +C
Sbjct: 1963 FELTH-NNDCLDIDECSSFFGQV-CRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNEC 2020
Query: 920 Q------HGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACN-CTAGAACDA 970
C ++ G+ C CP G+ E+ +C N C G+ +
Sbjct: 2021 VALPGSCSPGTCQNLEGSFRCICPPGYE-VKSENCIDIN----ECDEDPNICLFGSCTNT 2075
Query: 971 VNG-SCLCPAG----RRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGW- 1024
G CLCP G G RC +T + CF +G+C +
Sbjct: 2076 PGGFQCLCPPGFVLSDNGRRCFDT-----------RQSFCFTNFE----NGKCSVPKAFN 2120
Query: 1025 --MGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVR 1082
C P +GD C LC D V+ CP G G DV
Sbjct: 2121 TTKAKCCCSKMPGEGWGDPCE---LCPKD---DEVAFQDLCPYG-HGTVPSLHDTREDVN 2173
Query: 1083 AGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAAC 1140
C S G + G C G RC CP G+ D + G C C G C
Sbjct: 2174 E-CLESPGICSNGQCINTDGSFRCECPMGYNLD---------YTGVRCVDTDECSIGNPC 2223
Query: 1141 HHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENP-----ACHPATGT--CSC 1193
+ G C G C + PG +C + +C +NP C G+ C+C
Sbjct: 2224 GN--GTCTNVIGSFECNCNEGFEPGPM-MNCEDINEC-AQNPLLCAFRCMNTFGSYECTC 2279
Query: 1194 AAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGG-SCDAATGA--CRCPTGFLGTDCNLTCP 1250
GY Q+ C E L C + G C G C CP G C
Sbjct: 2280 PIGYALREDQKMCKD--LDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCV 2337
Query: 1251 QGRFGPNCTHVCGCGQGAACDPVTGT--CLCPPGRAGVRCERGCPQNRFGVG-------- 1300
C G + C + G+ C C G C NR G+
Sbjct: 2338 DEN---ECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTI 2394
Query: 1301 CEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELA-----------CP-------PGRYGA 1342
C+ S RN L S C G GW G CEL CP GR
Sbjct: 2395 CQMASSSRN--LVTKSECCCDGGRGW-GHQCELCPLPGTAQYKKICPHGPGYTTDGRDID 2451
Query: 1343 ACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWC-QHGAPCDP 1401
C + + N C G+ RC C+ G C L C Q PC+
Sbjct: 2452 ECKVMPNLCTNGQCINTMGSFRC-------FCKVGYTTDISGTSCIDLDECSQSPKPCNY 2504
Query: 1402 I------SGRCLCPAGF----HGHFCERGCEPGSFGEGCHQRC-DCDGGAPCDPVTGLCL 1450
I S +C CP G+ G C+ E + C C + GG C
Sbjct: 2505 ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCK------- 2557
Query: 1451 CPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREG 1506
CPPG + Q +C + +CG G C G C+ G
Sbjct: 2558 CPPGFT-----------QHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRG 2602
Score = 278 bits (711), Expect = 3e-74
Identities = 395/1580 (25%), Positives = 532/1580 (33%), Gaps = 354/1580 (22%)
Query: 98 QVYTTEARTVLRCCRGWMQQPDEEGCLSA-EC--SASLCFHGGRC--VPGSAQPCHCPPG 152
Q +E C G+ PD C EC + +C GG+C +PG + C C G
Sbjct: 1256 QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDIC-DGGQCTNIPGEYR-CLCYDG 1313
Query: 153 FQGP---RCQYDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL 208
F + DV+EC ++ C C NT GS++C C+ G+ + + C ++ C +
Sbjct: 1314 FMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI 1373
Query: 209 GNGGCQHHCVQLTIT-RHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVR--GL 265
G C H L I +C CR G+ +G C+ C+N C Q V G
Sbjct: 1374 GAHNCDMHASCLNIPGSFKCSCREGWI--GNGIKCIDLDECSNGTHQCSINAQCVNTPGS 1431
Query: 266 ARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQC 324
RC C G+ DG C DVDECA + C +G CLN G+++C C G+ +D R C
Sbjct: 1432 YRCACSEGF--TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
Query: 325 YRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS-PCCQ 383
I+ C N C++ C C GYELD C D+D+CAD C
Sbjct: 1490 QDID-----ECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVN 1544
Query: 384 QVCTNNPGGYECGCYAGYRLSADGCGCED--VDEC---ASSRGGCEHHCTNLAG----SF 434
+C N PG YEC C ++L+ G GC D V C RG C G
Sbjct: 1545 GLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRS 1604
Query: 435 QCSCEAGYRLHEDRRGCSPLE--EPMVDLDGELPFVRPLPHIAVLQD-----ELPQLFQD 487
C C G C P+ E G F RP P +L+D ELP L Q
Sbjct: 1605 SCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF-RPNPITIILEDIDECQELPGLCQG 1663
Query: 488 ----DDVGADEEEAELRGEHTLTEKFVC--LDDSFGHDCSLTCDDCR------------- 528
+ G+ + E +G + + +C +D+ F H C
Sbjct: 1664 GNCINTFGSFQCECP-QGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPE 1722
Query: 529 ----NGGTCLLGLDGCDCPEGWTGLIC-----------------------NETCPPDTFG 561
NGG + + C + G C N+ C P
Sbjct: 1723 YMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTP 1782
Query: 562 KNCSFSCSCQN--GGTCDSVTG------ACRCPPGVSGT----------NCEDGCPKGYY 603
F C N G T D TG C+ PG+ CE CP G+
Sbjct: 1783 GTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCE--CPTGFS 1840
Query: 604 GKH----CRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP--GCSEECQCV 657
C C+N + C+ PG Y C + P C + +C+
Sbjct: 1841 YNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCEC---AAGFKLSPNGACVDRNECL 1897
Query: 658 Q-PHTQS---CDKRDGS--CSCKAGFRGERCQA------ECELGYFGPGCWQACTCPVGV 705
+ P+ S C GS C C GF+ + Q ECE G G
Sbjct: 1898 EIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNG----------- 1946
Query: 706 ACDSVSGECGKRCPAGFQ---GEDC----------GQEC-------PVGTF--------- 736
C + G C GF+ DC GQ C +G+F
Sbjct: 1947 TCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYE 2006
Query: 737 ----GVNC--SSSC-----SCGGAPCHGVTG--QCRCPPGR--TGEDCEADCPEGRWGLG 781
G NC ++ C SC C + G +C CPPG E+C D E
Sbjct: 2007 LTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENC-IDINE------ 2059
Query: 782 CQEICPACQHAARCDPETG-ACLCLPGFV----GSRC----QDVCPAGWYGPSC------ 826
C E C + + G CLC PGFV G RC Q C + C
Sbjct: 2060 CDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAF 2119
Query: 827 ---QTRCSCA---NDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC-----NC 875
+ +C C+ +G P C P + Q C GH H C
Sbjct: 2120 NTTKAKCCCSKMPGEGWGDP----CELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNEC 2175
Query: 876 SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQG----HFGPGCEQRCQCQHGAACDHVSGA 931
G C +G C+ G RCE CP G + G C +C G C +G
Sbjct: 2176 LESPGICS--NGQCINTDGSF--RCE--CPMGYNLDYTGVRCVDTDECSIGNPCG--NGT 2227
Query: 932 CTCPAGWRGTFCEHACPAGFFGLDCRSACNCT-----AGAACDAVNGS--CLCPAG---R 981
CT G C G ++C C C GS C CP G R
Sbjct: 2228 CTNVIGSFECNCNEGFEPGPM-MNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALR 2286
Query: 982 RGPRCAETCPAHTYG-HNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLY 1038
+ + G H+C G C + G C C PG + C +
Sbjct: 2287 EDQKMCKDLDECAEGLHDCES-----RGMMCKNLIGTFMCICPPGMARRPDGEGC---VD 2338
Query: 1039 GDNCR-HSCLCQNGGTCDPVSGH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGL 1096
+ CR +C+NG + + + C C EG+ + ECL GL
Sbjct: 2339 ENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN-------------RQGL 2385
Query: 1097 CDPHTGRCLCPAG------WTGDKCQSPCLRGWFGEACAQRCSCP-PGAA-----CHHVT 1144
C + +C T +C RGW G C CP PG A C H
Sbjct: 2386 CFAEVLQTICQMASSSRNLVTKSECCCDGGRGW-GHQCE---LCPLPGTAQYKKICPHGP 2441
Query: 1145 G---------ACRCPPGFTGSG------------CEQACPPGSFGEDCAQMCQCPGE--- 1180
G C+ P +G C+ G C + +C
Sbjct: 2442 GYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKP 2501
Query: 1181 -NPACHPATGT--CSCAAGY----HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA 1233
N C G+ CSC GY G +C+ C+ LC GG
Sbjct: 2502 CNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF------T 2555
Query: 1234 CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP 1293
C+CP GF T + C CG + G C PG C+RG
Sbjct: 2556 CKCPPGF--TQHHTACIDNN---------ECGSQPSLCGAKGICQNTPGSFSCECQRGFS 2604
Query: 1294 QNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNN 1353
+ G+ CE C H C LG G C CP G +C N
Sbjct: 2605 LDATGLNCEDVDECDGN---HRCQHGCQNILG--GYRC--GCPQGYIQHYQWNQCVDENE 2657
Query: 1354 STCEPATGTCRCGPGFYGQACEHPCPPGF----HGAGCQGLCWCQHGAPCDPISGRCLCP 1409
+ A G+ C C CP GF + C + C +P + C
Sbjct: 2658 CSNPNACGSASCYNTLGSYKC--ACPSGFSFDQFSSACHDVNECSSSK--NPCNYGCSNT 2713
Query: 1410 AGFHGHFCERGCEPGSFGEG 1429
G G+ C GC PG + G
Sbjct: 2714 EG--GYLC--GCPPGYYRVG 2729
Score = 271 bits (693), Expect = 4e-72
Identities = 406/1631 (24%), Positives = 538/1631 (32%), Gaps = 341/1631 (20%)
Query: 109 RCCRGWMQQPDEEGCLSA-EC--SASLCFHGGRCV--PGSAQPCHCPPGFQ----GPRCQ 159
+C G+ + P ++ C+ EC + LC GRCV GS Q C C GF+ G C
Sbjct: 559 KCHAGFQRTPTKQACIDIDECIQNGVLC-KNGRCVNTDGSFQ-CICNAGFELTTDGKNC- 615
Query: 160 YDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 219
D DEC T N C+N GS+ C CKPGF L + R C ++ C HC+
Sbjct: 616 VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCIN 675
Query: 220 LTITRHRCQCRPGFQLQEDGRHCV---RRSPCAN--RNGSCMHR---------------- 258
+ RC C PG + DGR CV RS C + G C+
Sbjct: 676 -SEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPD 734
Query: 259 ------CQVVRGLARCE----CHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSF 307
CQ E C G + DG+ D++ECA CA+G C N +GS+
Sbjct: 735 YGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR---DINECALDPDICANGICENLRGSY 791
Query: 308 KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQ 367
+C C++GYE A GR C I+ +VN +NG C + T CTCP GY T+
Sbjct: 792 RCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRN----TPGSYSCTCPPGYVFRTET 847
Query: 368 RTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDV-----------DEC 416
TC D+++C +PC C NN G + C C G +LS+ G C D C
Sbjct: 848 ETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRC 907
Query: 417 ASSRGGC---EHHCTNLAGSFQCSCEAGYRLHEDRRG--------CSPLEEPMVDLDGEL 465
+ G C L ++ CE RG C + E V G
Sbjct: 908 EVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEV-FPGVC 966
Query: 466 PFVRPLPHIAVLQDELPQLFQDDDVGA--------------DEEEAELRGEHTLTEKF-- 509
P R + E P+ D G DE+E H + KF
Sbjct: 967 PNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC----IHPVPGKFRM 1022
Query: 510 -VCLDDSFGHDCSLTCDDCRNGGT------CLLGLDGCDCPEGWTGL-------ICNETC 555
C + G C++C GT C G + + TG C
Sbjct: 1023 DACC-CAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFP 1081
Query: 556 PPDTFGKNC-----SFSCSCQNGGTCD------SVTGACRCPPGVSGT--------NCED 596
T+GK C SF C C +G D + CR P + G+ + E
Sbjct: 1082 GMCTYGK-CRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFEC 1140
Query: 597 GCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQC 656
C +GY K NC + C R LC G TC S +C C
Sbjct: 1141 ECFEGYESGFMMMK-NCMDIDECER--NPLLCRGG--------TC----VNTEGSFQCDC 1185
Query: 657 VQPHTQSCDKRD----GSCSCKAGF-RGERC-------QAECELGYFGPGCWQACTCPVG 704
H S + D CS R +C Q C GY Q CT
Sbjct: 1186 PLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDI-- 1243
Query: 705 VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS-----------CGGAPCHG 753
C ++G C +C +C C G + SC+ C G C
Sbjct: 1244 DECMIMNGGCDTQCTNSEGSYEC--SCSEGYALMPDGRSCADIDECENNPDICDGGQCTN 1301
Query: 754 VTGQ--CRCPPGRTGE----------------------DCE-------ADCPEG----RW 778
+ G+ C C G +CE C G +
Sbjct: 1302 IPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKG 1361
Query: 779 GLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGP--SCQTRCSCANDG 836
GC ++ A CD +CL +PG C++ GW G C C+N
Sbjct: 1362 TTGCTDVDECEIGAHNCDMH-ASCLNIPGSFKCSCRE----GWIGNGIKCIDLDECSNGT 1416
Query: 837 HCHPATGHCSCAPGWTGFSCQRACDTGHWGP--DCSHPCNCSAGHGSCDAISGLCLCEAG 894
H C PG S + AC G G CS C+ C+ +G CL G
Sbjct: 1417 HQCSINAQCVNTPG----SYRCACSEGFTGDGFTCSDVDECAENINLCE--NGQCLNVPG 1470
Query: 895 YVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGL 954
CE C+ +C C V G C G C+ G
Sbjct: 1471 AYRCECEMGFTPASDSRSCQDIDECSFQNIC--VFGTCNNLPGMFHCICDDGYELDRTGG 1528
Query: 955 DCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPV 1014
+C C C VNG C+ GR C + G C D
Sbjct: 1529 NCTDIDECADPINC--VNGLCVNTPGRYECNCPPDFQLNPTGVGC-----------VDNR 1575
Query: 1015 HGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNG-------GTCDPVSG---HCACP 1064
G C+ G G L +C + R SC C G TC PV+ + CP
Sbjct: 1576 VGNCYLKFGPRGDGSL-SCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCP 1634
Query: 1065 EGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRG 1122
G + D+ C+ G GG C G +C CP G+ + C
Sbjct: 1635 GGEGFRPNPITIILEDIDE-CQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICED- 1692
Query: 1123 WFGEACAQRCSCPPGAACHHVTG--ACRCPPGFT----GSGC----EQACPPGSFGEDC- 1171
E A C PG C++ G C CPP + G C + C G C
Sbjct: 1693 -IDECFAHPGVCGPG-TCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCE 1750
Query: 1172 --------AQMCQC-----PGENPACH--PATGTC---SCAAGYHGPSCQQRCPPGRYGP 1213
+MC C N C P GT + G +
Sbjct: 1751 NELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDID 1810
Query: 1214 GCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACD 1271
C+++ G G C G+ C CPTGF D L C + C G
Sbjct: 1811 ECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCED---------IDECSNGDNLC 1861
Query: 1272 PVTGTCLCPPGRAGVRCERGCPQNRFGV-----GCEHTCSCRNGGLCHASNGS--CSCGL 1324
C+ PG C G + G C + + GLC GS C C
Sbjct: 1862 QRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHN 1921
Query: 1325 GWTGRHCELACPPGRYGAACHLECSCH--NNSTCEPATGTCRCGPGFYGQACEHPCPPGF 1382
G+ + C EC H N TC+ G+ C C PGF
Sbjct: 1922 GFKASQDQTMCMDVD-------ECERHPCGNGTCKNTVGSYNC-----------LCYPGF 1963
Query: 1383 ---HGAGCQGLCWCQ--HGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCD 1437
H C + C G C +GRC G C G E G+ C +C
Sbjct: 1964 ELTHNNDCLDIDECSSFFGQVCR--NGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECV 2021
Query: 1438 G-GAPCDPVT-------GLCLCPPGRSGATCN-LDCRRGQFGPSCTLHCDCGGGADCDPV 1488
C P T C+CPPG + N +D P+ L C P
Sbjct: 2022 ALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTN----TPG 2077
Query: 1489 SGQCHCVDGYM 1499
QC C G++
Sbjct: 2078 GFQCLCPPGFV 2088
Score = 251 bits (642), Expect = 3e-66
Identities = 387/1669 (23%), Positives = 545/1669 (32%), Gaps = 370/1669 (22%)
Query: 71 PVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSA 130
PV + GC C+G R Y G+ C Q + C+
Sbjct: 178 PVCENGCQNGGRCIGPNRCACVY-GFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTK 236
Query: 131 SLCF--------HGGRCVPGSAQPCHCP--PGFQGPRCQYDVDECRTHNGGCQH-RCVNT 179
+LC H P QPC P + CQ DVDEC+ G CQ C+NT
Sbjct: 237 TLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGGNCINT 295
Query: 180 PGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDG 239
GS+ C C G + ++ C I+ C++ G C+ T+ + C C G+ DG
Sbjct: 296 VGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDG 355
Query: 240 RHCV--RRSPCANR--NGSCMHRCQVVRGLARCECHVG--------------------YQ 275
C+ R C + NG C +C C G +
Sbjct: 356 SRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRR 415
Query: 276 LAADGKACEDVDECAA---------GLAQCAHG------------CLNTQGSFKCVCHAG 314
L DG + A G A +G G V AG
Sbjct: 416 LCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAG 475
Query: 315 YELGADGRQCYRIEM--EIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCI 371
G G + + + ++ C+ + C +G C T + C C GY+ D + CI
Sbjct: 476 VGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDAN-GDCI 534
Query: 372 DVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNL 430
DVD+C +PC C N PG Y C C+AG++ + C D+DEC + C++ C N
Sbjct: 535 DVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNT 594
Query: 431 AGSFQCSCEAGYRLHEDRRGCSPLEE----------PMVDLDGELPFVRPLPHIAVLQDE 480
GSFQC C AG+ L D + C +E ++ DG + +
Sbjct: 595 DGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFV------ 648
Query: 481 LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDC---------SLTCDDCRNGG 531
L + D +E + G + + + SF DC C D
Sbjct: 649 ---LAPNGRYCTDVDECQTPG-ICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
Query: 532 TCLLGLDGCDCPEGWTGLICNETC----PPDTFGKNC---------SFSCSCQNG----- 573
TC G+ C + G + C P FG+ C F C +G
Sbjct: 705 TCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITV 764
Query: 574 -----------------GTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNC-AN 615
G C+++ G+ RC NC G G++C C N
Sbjct: 765 DGRDINECALDPDICANGICENLRGSYRC-------NCNSGYEPDASGRNCIDIDECLVN 817
Query: 616 RGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKA 675
R C G C PG Y TCPP +E C+ + +S +G+C
Sbjct: 818 RLLCDN--GLCRNTPGSYS----CTCPPGYVFRTETETCEDIN-ECESNPCVNGACRNNL 870
Query: 676 GFRGERCQAECELGYFG--------PGCW---QACTCPVGVACDSVSGECGKRCPAGFQG 724
G C +L G CW Q C V + ++ EC A + G
Sbjct: 871 GSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAW-G 929
Query: 725 EDCGQ-----ECPVGTF---GVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEG 776
C + CP G GV C C P GV RC + CE CPEG
Sbjct: 930 SPCERCELDTACPRGLARIKGVTCEDVNECEVFP--GVCPNGRCVNSKGSFHCE--CPEG 985
Query: 777 RWGLGCQEIC--------------PACQHAARCDPETGACLCLPGFV-GSRCQD------ 815
G +C C H AC C G G+ C++
Sbjct: 986 LTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGT 1045
Query: 816 -----VCPAG--------------WYGP--SCQTRCSCANDGHCHPATG--HCSCAPGWT 852
+CP G +Y C+ G C G C C G+
Sbjct: 1046 KEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFA 1105
Query: 853 GFSCQRAC---DTGHWGPDC-----------SHPCNCSAGHGSCDAISGLCL----CEAG 894
+R C D PD S C C G+ S + C+ CE
Sbjct: 1106 LDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERN 1165
Query: 895 YV---GPRC-------EQQCPQGHFGPGCEQRC-----------QCQHGAACDHVSGA-- 931
+ G C + CP GH + C C++G C ++ G
Sbjct: 1166 PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQ 1224
Query: 932 CTCPAGWRGTFCEHAC----PAGFFGLDCRSACNCTAGA-ACDAVNGSCLCPAGRRGPRC 986
C+C G++ T C C + C + G+ C G L P GR C
Sbjct: 1225 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGR---SC 1281
Query: 987 AETCPAHTYGHNCSQACACFNGASCDPVHGQ--CHCAPGWMGPSCLQACPAGLYGDNCRH 1044
A+ C +G C + G+ C C G+M ++ C D +
Sbjct: 1282 ADI-------DECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSN 1334
Query: 1045 SCLCQNGGTCDPVSG----HC----ACPEGWAGLACEKECLPRDVRA-GCRHSGGCLNGG 1095
C+ G C+ G HC + +G G EC ++ A C CLN
Sbjct: 1335 ICMF---GECENTKGSFICHCQLGYSVKKGTTGCTDVDEC---EIGAHNCDMHASCLN-- 1386
Query: 1096 LCDPHTGRCLCPAGWTGD--KC--QSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPP 1151
P + +C C GW G+ KC C G + +C PG+ C C
Sbjct: 1387 --IPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSY------RCACSE 1438
Query: 1152 GFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRY 1211
GFTG G C+ + +C C G C G + C+ P
Sbjct: 1439 GFTGDGF-----------TCSDVDECAENINLCE--NGQCLNVPGAYRCECEMGFTPASD 1485
Query: 1212 GPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACD 1271
C+ + C C G C G C+ R G NCT + C C
Sbjct: 1486 SRSCQDIDECSFQNIC--VFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINC- 1542
Query: 1272 PVTGTCLCPPGRAGVRCERGCPQNRFGVGC----------------EHTCSCRNGGLCHA 1315
V G C+ PGR C N GVGC + + SC
Sbjct: 1543 -VNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGV 1601
Query: 1316 SNGSCSCGLG--WTGRHCELACPP---GRYGAAC---------HLECSCHNNSTCEPATG 1361
S SC C LG W G CE CPP Y C + + C+ G
Sbjct: 1602 SRSSCCCSLGKAW-GNPCE-TCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPG 1659
Query: 1362 TCR---CGPGFYGQACEHPCPPGFHGAG----CQGLCWC-QHGAPCDP-------ISGRC 1406
C+ C F CE CP G++ + C+ + C H C P + C
Sbjct: 1660 LCQGGNCINTFGSFQCE--CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTC 1717
Query: 1407 LCPAGF----HGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLC 1451
+CP + GH C + SF + C+ P + +C C
Sbjct: 1718 ICPPEYMQVNGGHNCMDMRK--SFCYRSYNGTTCENELPFNVTKRMCCC 1764
Score = 225 bits (574), Expect = 2e-58
Identities = 405/1650 (24%), Positives = 551/1650 (33%), Gaps = 378/1650 (22%)
Query: 83 CVGHERRTVYYMGYRQVYTTE----ARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGR 138
CV R+ Y G ++ A T CC E C S FHG
Sbjct: 697 CVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHG-- 754
Query: 139 CVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHR-CVNTPGSYLCECKPGFRLHTDS 197
C G D++EC C + C N GSY C C G+
Sbjct: 755 ---------LCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASG 805
Query: 198 RTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANR---NGS 254
R C+ I+ C + C + + T + C C PG+ + + C + C + NG+
Sbjct: 806 RNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA 865
Query: 255 CMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC-LNTQGS-FKCVCH 312
C + G CEC G +L++ G C D + L C +N G+ K C
Sbjct: 866 CRNNL----GSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECC 921
Query: 313 AGYELGAD-GRQCYRIEM----------------EIVNSCEANNGGCSHG-CSHTSAGPL 354
A LGA G C R E+ E VN CE G C +G C ++
Sbjct: 922 A--TLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFH 979
Query: 355 CTCPRGYELDTDQRTCIDV-----------DDCA---------DSPCCQ---------QV 385
C CP G LD R C+D+ D+C D+ CC +
Sbjct: 980 CECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEE 1039
Query: 386 CTNNPGGYE----CGCYAGYRLSADGCG----CEDVDECASSRGGCEH-HCTNLAGSFQC 436
C PG E C AG+ D +D++EC + G C + C N GSF+C
Sbjct: 1040 CPK-PGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKC 1098
Query: 437 SCEAGYRLHEDRRGCSPLEEPMV--DLDGELPFVR-PLPHIAVLQDELPQLFQDDDVGAD 493
C +G+ L + R C+ ++E + DL G V P + F D
Sbjct: 1099 RCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMD 1158
Query: 494 EEEAELR------GEHTLTEKFVCLDDSFGH-------------DCSLTCDDCRNGGTC- 533
+E E G TE D GH +CSL+ + CRNG
Sbjct: 1159 IDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVN 1218
Query: 534 LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTN 593
++G C C G+ PD G C NGG CD+ C G +
Sbjct: 1219 MIGTYQCSCNPGY-------QATPDRQGCTDIDECMIMNGG-CDT---QCTNSEGSYECS 1267
Query: 594 CEDGCPKGYYGKHCRKKCNCANR------GRCHRLYG--ACLCDPGLYGRFCHLTCPPWA 645
C +G G+ C C N G+C + G CLC G TC
Sbjct: 1268 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN 1327
Query: 646 FGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGERCQA------ECELGYFGPGCWQ 697
S C + C+ GS C C+ G+ ++ ECE+G
Sbjct: 1328 ECDLNSNICMFGE-----CENTKGSFICHCQLGYSVKKGTTGCTDVDECEIG-------- 1374
Query: 698 ACTCPVGVACDSVSGECGKRCPAGFQGEDCG----QECPVGTFGVNCSSSCSCGGAPCHG 753
A C + +C ++ G C G+ G EC GT CS + C P
Sbjct: 1375 AHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTH--QCSINAQCVNTP--- 1429
Query: 754 VTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRC 813
+ +C C G TG+ G C ++ ++ C E G CL +PG C
Sbjct: 1430 GSYRCACSEGFTGD-----------GFTCSDVDECAENINLC--ENGQCLNVPGAYRCEC 1476
Query: 814 QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC 873
+ SCQ C+ C G C+ PG C + G +C+
Sbjct: 1477 EMGFTPASDSRSCQDIDECSFQNIC--VFGTCNNLPGMFHCICDDGYELDRTGGNCTDID 1534
Query: 874 NCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACT 933
C+ + ++GLC+ G C G GC D+ G C
Sbjct: 1535 ECA---DPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGC-----------VDNRVGNCY 1580
Query: 934 CPAGWRG---TFCEHACPAGFFGLDCRSACNCTAGAA-------CDAVNGS---CLCPAG 980
G RG C G RS+C C+ G A C VN + LCP G
Sbjct: 1581 LKFGPRGDGSLSCNTEIGVGV----SRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGG 1636
Query: 981 ---RRGP---------RCAETCPAHTYGHNC-----SQACACFNG-------ASCDPVHG 1016
R P C E P G NC S C C G C+ +
Sbjct: 1637 EGFRPNPITIILEDIDECQE-LPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDI-D 1694
Query: 1017 QCHCAPGWMGP-SCLQA-------CPAGLYGDNCRHSCL---------CQNGGTCD---- 1055
+C PG GP +C CP N H+C+ NG TC+
Sbjct: 1695 ECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELP 1754
Query: 1056 -PVSGHCACPEGWAGLACEKEC--LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG 1112
V+ C G A K C P A + G + G D HTG+ +
Sbjct: 1755 FNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAV-----DI 1809
Query: 1113 DKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGED 1170
D+C+ CA C + G+ C CP GF+ + C +
Sbjct: 1810 DECKE------IPGICA-------NGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSN 1856
Query: 1171 CAQMCQCPGENPAC--HPATGTCSCAAGYH---GPSCQQRCPPGRYGPGCEQLCGCLNGG 1225
+CQ N C P + C CAAG+ +C R C ++ + G
Sbjct: 1857 GDNLCQ---RNADCINSPGSYRCECAAGFKLSPNGACVDR-------NECLEIPNVCSHG 1906
Query: 1226 SCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNC-THVCGCGQGAACDPVTGT--CLCP 1280
C G+ C C GF + C C H CG G C G+ CLC
Sbjct: 1907 LCVDLQGSYQCICHNGFKASQDQTMCMD---VDECERHPCGNG---TCKNTVGSYNCLCY 1960
Query: 1281 PGRA-----------------GVRCERGCPQNRFGVGCEHTCSCRNG------------- 1310
PG G C G N G C C G
Sbjct: 1961 PGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIG---SFKCLCNEGYELTPDGKNCIDT 2017
Query: 1311 GLCHASNGSCSCGLGWTGRHCE----LACPPGRYGAACHLECSCHNNSTCEP-----ATG 1361
C A GSCS G T ++ E CPPG Y +C + + C+ G
Sbjct: 2018 NECVALPGSCSPG---TCQNLEGSFRCICPPG-YEVKSE---NCIDINECDEDPNICLFG 2070
Query: 1362 TCRCGPGFYGQACEHPCPPGF----HGAGC----QGLCWCQHGAPCDPISGRCLCPAGFH 1413
+C PG G C CPPGF +G C Q C+ +G+C P F+
Sbjct: 2071 SCTNTPG--GFQC--LCPPGFVLSDNGRRCFDTRQSFCFTNFE------NGKCSVPKAFN 2120
Query: 1414 GHFCERGCE--PG-SFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFG 1470
+ C PG +G+ C + C D D V LCP G G +L R
Sbjct: 2121 TTKAKCCCSKMPGEGWGDPC-ELCPKD-----DEVAFQDLCPYGH-GTVPSLHDTREDVN 2173
Query: 1471 PSCTLHCDCGGGADCDPVSG--QCHCVDGY 1498
C G C G +C C GY
Sbjct: 2174 ECLESPGICSNG-QCINTDGSFRCECPMGY 2202
Score = 214 bits (546), Expect = 4e-55
Identities = 372/1584 (23%), Positives = 502/1584 (31%), Gaps = 351/1584 (22%)
Query: 110 CCRGWMQQPDEEGCLSAECSASL-----------CFHGGRCVPGSAQPCHCPPGFQGPRC 158
C G+ +P+ C S + S++ C +GG C C C G+ G C
Sbjct: 119 CGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDH---CQCQKGYIGTYC 175
Query: 159 QYDVDECRTHNGGCQHRCVNTPGSYLCECKPGF---RLHTDSRTCLAINSCALGNGGCQH 215
V E NGG RC+ G C C GF + D RT + N CQ
Sbjct: 176 GQPVCENGCQNGG---RCI---GPNRCACVYGFTGPQCERDYRTGPCFTQ--VNNQMCQG 227
Query: 216 HCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQ 275
+ T+ C CA + H C++ + C G+
Sbjct: 228 QLTGIVCTKTLC--------------------CATIGRAWGHPCEMCPAQPQ-PCRRGFI 266
Query: 276 LAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNS 334
AC+DVDEC A C G C+NT GSF+C C AG++ ++C E ++
Sbjct: 267 PNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKC-----EDIDE 321
Query: 335 CEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCID------VDDCADSPCCQQV-- 385
C G C G CS+T C CPRGY TD CID + C Q++
Sbjct: 322 CSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPG 381
Query: 386 ------CTNNPGGYEC-------------GCYAGYRLSADGCGCEDVDECASSRGGCEHH 426
C PG C G RL DG + A SR G
Sbjct: 382 RMTKMQCCCEPG--RCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPG---- 435
Query: 427 CTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAV-------LQD 479
G+ G+ + G P + + G F + V +
Sbjct: 436 --GTGGN-------GFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIIT 486
Query: 480 ELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGH------DCSLTCDDCRN---- 529
L L Q D+ L G T + + G+ DC + D+C +
Sbjct: 487 GLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDC-IDVDECTSNPCT 545
Query: 530 GGTCL--LGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPP 587
G C+ G C C G+ + C QNG C + G C
Sbjct: 546 NGDCVNTPGSYYCKCHAGFQRTPTKQAC--------IDIDECIQNGVLCKN--GRCVNTD 595
Query: 588 GVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFG 647
G C G GK+C C C L G C+ + G + C P +
Sbjct: 596 GSFQCICNAGFELTTDGKNCVDHDECTTTNMC--LNGMCINEDGSFKCICK---PGFVLA 650
Query: 648 PG---CS--EECQ----CVQPHTQSCDKRDGS--CSCKAGFRGERCQAECELGYFGPGCW 696
P C+ +ECQ C+ H C +GS C C G C + C+
Sbjct: 651 PNGRYCTDVDECQTPGICMNGH---CINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCY 707
Query: 697 -----QACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPV---GTFGVNCSSSCS--- 745
C P A EC P GE C Q CP F CSS
Sbjct: 708 GGIKKGVCVRPFPGAV--TKSECCCANPDYGFGEPC-QPCPAKNSAEFHGLCSSGVGITV 764
Query: 746 --------------CGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQH 791
C C + G RC +C + G C +I +
Sbjct: 765 DGRDINECALDPDICANGICENLRGSYRC-------NCNSGYEPDASGRNCIDIDECLVN 817
Query: 792 AARCD-------PETGACLCLPGFV----GSRCQDVCPAGWYGPSCQTRCSCANDGHCHP 840
CD P + +C C PG+V C+D+ C++ C N G C
Sbjct: 818 RLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDI-------NECESN-PCVN-GACRN 868
Query: 841 ATG--HCSCAPG----WTGFSC-------------QRACDTGHWGPDCSHPCNCSAG--- 878
G +C C+PG TG C C+ G C + G
Sbjct: 869 NLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAW 928
Query: 879 HGSCDAISGLCLCEAGYV---GPRCEQ---------QCPQGH-FGPGCEQRCQCQHGAAC 925
C+ C G G CE CP G C+C G
Sbjct: 929 GSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTL 988
Query: 926 DHVSGAC------TCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSC---- 975
D C C W C H P G F +D AC C GAA C
Sbjct: 989 DGTGRVCLDIRMEQCYLKWDEDECIHPVP-GKFRMD---ACCCAVGAAWGTECEECPKPG 1044
Query: 976 ------LCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC 1029
LCP G + + + ++ C F G +G+C G C
Sbjct: 1045 TKEYETLCPRGAGFANRGDVLTGRPFYKDINE-CKAFPGMC---TYGKCRNTIGSFKCRC 1100
Query: 1030 LQACPAGLYGDNCRHSCLCQ------NGGTC--DPVSGHCACPEGW-AGLACEKECLPRD 1080
+ NC C+ G C P S C C EG+ +G K C+ D
Sbjct: 1101 NSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDID 1160
Query: 1081 VRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGA 1138
C + GG C G +C CP G + C+ E C G
Sbjct: 1161 ---ECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVD--INECSLSDNLCRNGK 1215
Query: 1139 ACHHV-TGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT--CSCAA 1195
+ + T C C PG+ + Q C + ++C M G + C + G+ CSC+
Sbjct: 1216 CVNMIGTYQCSCNPGYQATPDRQGC---TDIDEC--MIMNGGCDTQCTNSEGSYECSCSE 1270
Query: 1196 GY----HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG--ACRCPTGFLGTDCNLTC 1249
GY G SC CE +GG C G C C GF+ + TC
Sbjct: 1271 GYALMPDGRSCADI-------DECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTC 1323
Query: 1250 PQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN 1309
+++C G+ C+ G+ +C C+ G + GC C
Sbjct: 1324 IDVNECDLNSNICMFGE---CENTKGSFIC-------HCQLGYSVKKGTTGCTDVDECEI 1373
Query: 1310 GGL---CHAS------NGSCSCGLGWTGR-------------------HCELACPPGRYG 1341
G HAS + CSC GW G + + PG Y
Sbjct: 1374 GAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 1433
Query: 1342 AACH-------LECS-----CHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQG 1389
AC CS N + CE G C PG Y CE P CQ
Sbjct: 1434 CACSEGFTGDGFTCSDVDECAENINLCE--NGQCLNVPGAYRCECEMGFTPASDSRSCQD 1491
Query: 1390 LCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLC 1449
+ C C + G C G C+ G E G C +C P + V GLC
Sbjct: 1492 IDECSFQNIC--VFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDEC--ADPINCVNGLC 1547
Query: 1450 LCPPGRSGATCNLDCRRGQFGPSC 1473
+ PGR C D + G C
Sbjct: 1548 VNTPGRYECNCPPDFQLNPTGVGC 1571
Score = 137 bits (346), Expect = 6e-32
Identities = 266/1102 (24%), Positives = 342/1102 (31%), Gaps = 238/1102 (21%)
Query: 527 CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCP 586
C NGGTC D C C +G+ G C + + CQNGG C G RC
Sbjct: 153 CMNGGTC--ADDHCQCQKGYIGTYCGQPVCEN----------GCQNGGRC---IGPNRC- 196
Query: 587 PGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAF 646
C G+ G C + G C +C L G C T
Sbjct: 197 ----------ACVYGFTGPQCERD---YRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATI 243
Query: 647 GPGCSEECQCVQPHTQSCDK------RDGSCSCKAGFRGERCQAECELGYFGPGCWQACT 700
G C+ Q C + R G+C + CQA PG Q
Sbjct: 244 GRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-----DVDECQAI-------PGICQGGN 291
Query: 701 CPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS-----CGGAPCHGVT 755
C V S EC RCPAG + + Q+C CS C C
Sbjct: 292 CINTVG----SFEC--RCPAGHKQSETTQKC-------EDIDECSIIPGICETGECSNTV 338
Query: 756 GQ--CRCPPGRTGEDCEADCPEGRWGL--------GCQEICPACQHAARCDPETGACL-- 803
G C CP G + C + R G+ C + P +C E G C
Sbjct: 339 GSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGI 398
Query: 804 -CLPGFVGSR--------CQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGF 854
+P R C D P G S +R P+ PG TGF
Sbjct: 399 GTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGF 458
Query: 855 ------------SCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCL---CEAGYVGPR 899
G GP + + C + LCL C R
Sbjct: 459 IPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYR 518
Query: 900 CEQQCPQGH---FGPGCEQRCQCQHGAA----CDHVSGA--CTCPAGWRGTFCEHACPAG 950
CE C G+ C +C C + G+ C C AG++ T + AC
Sbjct: 519 CE--CNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQAC--- 573
Query: 951 FFGLD--CRSACNCTAGAACDAVNGS--CLCPAGRRGPRCAETCPAHTYGHNCSQACACF 1006
+D ++ C G C +GS C+C AG + C H C+ C
Sbjct: 574 -IDIDECIQNGVLCKNG-RCVNTDGSFQCICNAGFELTTDGKNCVDH---DECTTTNMCL 628
Query: 1007 NGASCDPVHG--QCHCAPGWMGPSCLQACPAGLY---GDNCRHSCLCQNGGTCDPV-SGH 1060
NG C G +C C PG++ P G Y D C+ +C NG + S
Sbjct: 629 NG-MCINEDGSFKCICKPGFV------LAPNGRYCTDVDECQTPGICMNGHCINSEGSFR 681
Query: 1061 CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL 1120
C CP G A + C+ +R+ C GG G P P T +C
Sbjct: 682 CDCPPGLAVGMDGRVCVDTHMRSTC--YGGIKKGVCVRPF------PGAVTKSECCCANP 733
Query: 1121 RGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGE 1180
FGE C Q C A H G C G T G + +C +
Sbjct: 734 DYGFGEPC-QPCPAKNSAEFH---GLCSSGVGITVDG--------------RDINECALD 775
Query: 1181 NPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCL-NGGSCDAATGACRCPTG 1239
C A G C G + +C P G C + CL N CD G CR G
Sbjct: 776 PDIC--ANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCD--NGLCRNTPG 831
Query: 1240 FLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDP-VTGTCLCPPGRAGVRCERGCPQNRFG 1298
+ TCP G T C +P V G C G C G + G
Sbjct: 832 ----SYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTG 887
Query: 1299 VGC-------------EHTCSCRNGGLCHASNGSCSCGLGWTG--RHCEL--ACPPGRYG 1341
+ C + C G S + G W CEL ACP G
Sbjct: 888 LICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACP---RG 944
Query: 1342 AACHLECSCHNNSTCEPATGTCRCGPGFYGQACEH-PCPPGFHGAGCQGLC--------- 1391
A +C + + CE G C G + H CP G G +C
Sbjct: 945 LARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCY 1004
Query: 1392 --W----CQHGAPCDPISGRCLCPAG-FHGHFCERGCEPGS--------FGEGCHQRCDC 1436
W C H P C C G G CE +PG+ G G R D
Sbjct: 1005 LKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDV 1064
Query: 1437 DGGAP-------CDPVTGLCLCPPGR-----------SGATCNLDCRRGQFGPSCTLHCD 1478
G P C G+C R SG +++ R C + D
Sbjct: 1065 LTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPD 1124
Query: 1479 CGGGADC--DPVSGQCHCVDGY 1498
G C P S +C C +GY
Sbjct: 1125 LCGSGICVNTPGSFECECFEGY 1146
Score = 121 bits (304), Expect = 5e-27
Identities = 296/1211 (24%), Positives = 384/1211 (31%), Gaps = 297/1211 (24%)
Query: 524 CDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCS--------CQNG-- 573
C+ G C ++ C TG++C +T T G+ C C+ G
Sbjct: 207 CERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFI 266
Query: 574 -----GTCDSVTGACRCPPGV-SGTNC-------EDGCPKGYYGKHCRKKCNCANRGRCH 620
G C V C+ PG+ G NC E CP G+ +KC + C
Sbjct: 267 PNIRTGACQDV-DECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCE--DIDECS 323
Query: 621 RLYGAC---LCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKR--DGSCSCKA 675
+ G C C + FC CP ++ +C+ T C +G C+ +
Sbjct: 324 IIPGICETGECSNTVGSYFC--VCPRGYV--TSTDGSRCIDQRTGMCFSGLVNGRCAQEL 379
Query: 676 GFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGE-----CGKRCPAGFQGEDCGQE 730
R + Q CE G CW T P AC E C P G G
Sbjct: 380 PGRMTKMQCCCEPG----RCWGIGTIP--EACPVRGSEEYRRLCMDGLPMGGIPGSAGSR 433
Query: 731 CPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLG--------C 782
P GT G N + G G TG P G G G G
Sbjct: 434 -PGGT-GGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTIL 491
Query: 783 QEICPACQHAA------RCDPETGA--CLCLPGF---VGSRCQDVCPAGWYGPSCQTRCS 831
+ C+H A RC P + C C G+ C DV C T
Sbjct: 492 NQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDV-------DEC-TSNP 543
Query: 832 CANDGHC--HPATGHCSCAPGWTGFSCQRA-------------CDTGHW-GPDCSHPCNC 875
C N G C P + +C C G+ ++A C G D S C C
Sbjct: 544 CTN-GDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCIC 602
Query: 876 SAG------------HGSCD----AISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQC 919
+AG H C ++G+C+ E G C+ G C +C
Sbjct: 603 NAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC 662
Query: 920 QHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDC-----RSACN-------CTAGAA 967
Q C ++G C G C G G C RS C C
Sbjct: 663 QTPGIC--MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFP 720
Query: 968 CDAVNGSCLC--PAGRRGPRCAETCPAHT---YGHNCSQA------------CA-----C 1005
C C P G C + CPA + CS CA C
Sbjct: 721 GAVTKSECCCANPDYGFGEPC-QPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDIC 779
Query: 1006 FNGASCDPVHG--QCHCAPGW----MGPSCLQACPAGLYGDNCRHSCLCQNGGTC--DPV 1057
NG C+ + G +C+C G+ G +C+ D C + L + G C P
Sbjct: 780 ANGI-CENLRGSYRCNCNSGYEPDASGRNCIDI-------DECLVNRLLCDNGLCRNTPG 831
Query: 1058 SGHCACPEGWA----GLACE--KECLPRD-VRAGCRHSGGCLN------------GGLC- 1097
S C CP G+ CE EC V CR++ G N G +C
Sbjct: 832 SYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICI 891
Query: 1098 DPHTGRC-------LCPAGWTGDKCQSPC---LRGWFGEACAQRC----SCPPGAA---- 1139
D G C C G +S C L +G C +RC +CP G A
Sbjct: 892 DSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPC-ERCELDTACPRGLARIKG 950
Query: 1140 --------CHHVTGAC---RCPPGFTGSGCEQACPPGSFGEDCAQMC------QCP---G 1179
C G C RC CE CP G + ++C QC
Sbjct: 951 VTCEDVNECEVFPGVCPNGRCVNSKGSFHCE--CPEGLTLDGTGRVCLDIRMEQCYLKWD 1008
Query: 1180 ENPACHPATG-----TCSCAAG-YHGPSCQQRCPPG--RYGPGCEQLCGCLNGG------ 1225
E+ HP G C CA G G C++ PG Y C + G N G
Sbjct: 1009 EDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGR 1068
Query: 1226 -------SCDA-----ATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCG-QGAACDP 1272
C A G CR G CN NCT + C C
Sbjct: 1069 PFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCG- 1127
Query: 1273 VTGTCLCPPGRAGVRCERG------CPQNRFGVG-CEHTCSCRNGGLCHASNGS--CSCG 1323
+G C+ PG C G +N + CE GG C + GS C C
Sbjct: 1128 -SGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCP 1186
Query: 1324 LGWTGRHCELACPPGRYGAACHLECSCHN----NSTCEPATGT--CRCGPGFYG----QA 1373
LG EL+ P R ECS + N C GT C C PG+ Q
Sbjct: 1187 LGH-----ELS--PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQG 1239
Query: 1374 CEHPCPPGFHGAGCQGLCWCQHGA-PCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQ 1432
C GC C G+ C G L P G R C + + C
Sbjct: 1240 CTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDG-------RSC---ADIDECEN 1289
Query: 1433 RCD-CDGGAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVS 1489
D CDGG C + G CLC G ++D + C L+ + +C+
Sbjct: 1290 NPDICDGG-QCTNIPGEYRCLC---YDGFMASMDMKTCIDVNECDLNSNICMFGECENTK 1345
Query: 1490 GQ--CHCVDGY 1498
G CHC GY
Sbjct: 1346 GSFICHCQLGY 1356
Score = 119 bits (299), Expect = 2e-26
Identities = 196/756 (25%), Positives = 248/756 (32%), Gaps = 168/756 (22%)
Query: 781 GCQEICPACQHAAR---CDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS--CAND 835
G Q I P C+++ C C C G + S C G +CS C N
Sbjct: 107 GNQCIVPICRNSCGDGFCS-RPNMCTCSSGQISSTC---------GSKSIQQCSVRCMNG 156
Query: 836 GHCHPATGHCSCAPGWTGFSC-QRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAG 894
G C A HC C G+ G C Q C+ G C G G C C C G
Sbjct: 157 GTC--ADDHCQCQKGYIGTYCGQPVCENG-----------CQNG-GRCIG-PNRCACVYG 201
Query: 895 YVGPRCEQQCPQGH-FGPGCEQRCQCQ-HGAACDHVSGACTCPAGWRGTFCEHACPA--- 949
+ GP+CE+ G F Q CQ Q G C T W G CE CPA
Sbjct: 202 FTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW-GHPCE-MCPAQPQ 259
Query: 950 ----GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAET-------CPAHTYGHN 998
GF AC C A+ G C +G C T CPA GH
Sbjct: 260 PCRRGFIPNIRTGACQDV--DECQAIPGIC------QGGNCINTVGSFECRCPA---GHK 308
Query: 999 CSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVS 1058
S+ C+ + +C PG +C+ G + V
Sbjct: 309 QSETT-----QKCEDI-DECSIIPG-----------------------ICETGECSNTVG 339
Query: 1059 GH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR-----CLCPAGWTG 1112
+ C CP G+ C+ D R G S G +NG GR C C G
Sbjct: 340 SYFCVCPRGYVTSTDGSRCI--DQRTGMCFS-GLVNGRCAQELPGRMTKMQCCCEPG--- 393
Query: 1113 DKCQSPCLRGWFGEACAQRCS------CPPGAACHHVTGACRCPPGFT-GSGCEQACPPG 1165
+C G EAC R S C G + G+ PG T G+G +
Sbjct: 394 -RCWG---IGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGN 449
Query: 1166 SFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGG 1225
+G PG N P G AG GP + C+ G
Sbjct: 450 GYGPGGTGFIPIPGGN-GFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNG 508
Query: 1226 SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVT-GTCLCPPGRA 1284
C + RC +CN+ Q G +C V C +P T G C+ PG
Sbjct: 509 RCIPTVSSYRC-------ECNMGYKQDANG-DCIDVDEC----TSNPCTNGDCVNTPGSY 556
Query: 1285 GVRCERGCPQNRFGVGCEHTCSC-RNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAA 1343
+C G + C C +NG LC NG C G C G
Sbjct: 557 YCKCHAGFQRTPTKQACIDIDECIQNGVLC--KNGRCVNTDGSFQCICNAGFELTTDGKN 614
Query: 1344 C--HLECSCHN---NSTCEPATGTCRCGPGFYGQACEHPCPPGF----HGAGCQGLCWCQ 1394
C H EC+ N N C G+ +C C PGF +G C + CQ
Sbjct: 615 CVDHDECTTTNMCLNGMCINEDGSFKC-----------ICKPGFVLAPNGRYCTDVDECQ 663
Query: 1395 HGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGC---HQRCDCDGGAPCDPVTGLCLC 1451
C ++G C+ G C G G G C H R C GG G+C+
Sbjct: 664 TPGIC--MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK----KGVCVR 717
Query: 1452 PPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDP 1487
P GA +C C + D G G C P
Sbjct: 718 P--FPGAVTKSEC--------CCANPDYGFGEPCQP 743
Score = 82.4 bits (202), Expect = 3e-15
Identities = 82/298 (27%), Positives = 106/298 (35%), Gaps = 69/298 (23%)
Query: 187 CKPGFRLHTDSRTCLAI---NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 243
C PG++ C+ NSC G+G C + C C G G +
Sbjct: 97 CCPGWKTLPGGNQCIVPICRNSC--GDGFCSRP--------NMCTCSSGQISSTCGSKSI 146
Query: 244 RRSP--CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCL 301
++ C N G+C C+C GY G C G C +GC
Sbjct: 147 QQCSVRCMN-GGTCADD--------HCQCQKGYI----GTYC--------GQPVCENGCQ 185
Query: 302 NTQ---GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS--------------- 343
N G +C C G+ G QC R + NN C
Sbjct: 186 NGGRCIGPNRCACVYGFT----GPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCA 241
Query: 344 -------HGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYE 394
H C A P C RG+ + C DVD+C P C C N G +E
Sbjct: 242 TIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFE 300
Query: 395 CGCYAGYRLSADGCGCEDVDECASSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRRGC 451
C C AG++ S CED+DEC+ G CE C+N GS+ C C GY D C
Sbjct: 301 CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC 358
Score = 81.6 bits (200), Expect = 5e-15
Identities = 93/345 (26%), Positives = 122/345 (35%), Gaps = 61/345 (17%)
Query: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRC-QYDVDECRTH 168
CC GW P C+ C S C G P C C G C + +C
Sbjct: 97 CCPGWKTLPGGNQCIVPICRNS-CGDGFCSRPNM---CTCSSGQISSTCGSKSIQQCSV- 151
Query: 169 NGGCQHRCVN--TPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHR 226
RC+N T C+C+ G+ + T + N C G G C I +R
Sbjct: 152 ------RCMNGGTCADDHCQCQKGY-IGTYCGQPVCENGCQNG-GRC--------IGPNR 195
Query: 227 CQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQ---VVRGLARCECHVGYQLAADGKAC 283
C C GF + R R PC + + M + Q +V C +G A G C
Sbjct: 196 CACVYGFTGPQCERD-YRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIG---RAWGHPC 251
Query: 284 EDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS 343
E C A C G + + C + V+ C+A G C
Sbjct: 252 E---MCPAQPQPCRRGFIPNIRTGAC--------------------QDVDECQAIPGICQ 288
Query: 344 HG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAG 400
G C +T C CP G++ + C D+D+C+ P C C+N G Y C C G
Sbjct: 289 GGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRG 348
Query: 401 YRLSADGCGCED--VDECASS--RGGCEHHCTNLAGSFQCSCEAG 441
Y S DG C D C S G C QC CE G
Sbjct: 349 YVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
Score = 79.3 bits (194), Expect = 3e-14
Identities = 57/181 (31%), Positives = 74/181 (40%), Gaps = 15/181 (8%)
Query: 109 RCCRGWMQQPDEEGCL-SAECSA--SLCFHGGRC--VPGSAQPCHCPPGFQ----GPRCQ 159
+C G+ Q C+ + EC + SLC G C PGS C C GF G C+
Sbjct: 2557 KCPPGFTQH--HTACIDNNECGSQPSLCGAKGICQNTPGSFS-CECQRGFSLDATGLNCE 2613
Query: 160 YDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 219
DVDEC N CQH C N G Y C C G+ H C+ N C+ N C
Sbjct: 2614 -DVDEC-DGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYN 2671
Query: 220 LTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAAD 279
T+ ++C C GF + C + C++ C + C G C C GY
Sbjct: 2672 -TLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQ 2730
Query: 280 G 280
G
Sbjct: 2731 G 2731
Score = 40.0 bits (92), Expect = 0.017
Identities = 44/152 (28%), Positives = 48/152 (31%), Gaps = 22/152 (14%)
Query: 1378 CPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH----QR 1433
C FH C G G C R C GF C G C Q+
Sbjct: 89 CGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQ 148
Query: 1434 CD--CDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ 1491
C C G C C C G G C GQ P C C GG P +
Sbjct: 149 CSVRCMNGGTC--ADDHCQCQKGYIGTYC------GQ--PVCENGCQ-NGGRCIGP--NR 195
Query: 1492 CHCVDGYMGPTCREG---GPLRLPENPSLAQG 1520
C CV G+ GP C GP N + QG
Sbjct: 196 CACVYGFTGPQCERDYRTGPCFTQVNNQMCQG 227
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 295 bits (754), Expect = 3e-79
Identities = 428/1708 (25%), Positives = 573/1708 (33%), Gaps = 481/1708 (28%)
Query: 109 RCCRGWMQQPDEEGCLSA-EC--SASLCFHGGRCV--PGSAQPCHCPPGFQG-----PRC 158
RC G+ +E C EC S LC G +CV PG + C C G++ C
Sbjct: 1054 RCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTPGDFE-CKCDEGYESGFMMMKNC 1111
Query: 159 QYDVDECRTHNGGCQHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH-H 216
D+DEC+ C+ C NT GSY CEC PG +L + C+ IN C L C +
Sbjct: 1112 M-DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGR 1170
Query: 217 CVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQL 276
CV L I +++C C PG+ D CV C+ NG C C G C C G+ L
Sbjct: 1171 CVNL-IGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
Query: 277 AADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSC 335
D ++C D+DEC C G C N G ++C+C+ G+ D + C VN C
Sbjct: 1230 MPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVD-----VNEC 1284
Query: 336 EANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC---ADSPCCQQVCTNNPG 391
+ N C G C +T +C C GY + C D+++C A + VCTN G
Sbjct: 1285 DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAG 1344
Query: 392 GYECGCYAGYRLSADGCGCEDVDECASSRGGCEHH--CTNLAGSFQCSCEAGYRLHEDRR 449
++C C G+ DG C D+DEC++ C H C N GS++C C+ GY D
Sbjct: 1345 SFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGF 1400
Query: 450 GCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKF 509
C+ L+E +L+ L
Sbjct: 1401 TCTDLDECSENLN------------------------------------------LCGNG 1418
Query: 510 VCLDDSFGHDCSLTCD----DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCS 565
CL+ G+ C CD +G C +D C P IC FG
Sbjct: 1419 QCLNAPGGYRCE--CDMGFVPSADGKAC-EDIDECSLPN-----IC-------VFG---- 1459
Query: 566 FSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA 625
TC ++ G RC CE G G +C C + C + G
Sbjct: 1460 ---------TCHNLPGLFRC-------ECEIGYELDRSGGNCTDVNECLDPTTC--ISGN 1501
Query: 626 CLCDPGLYGRFCHLTCPP-WAFGPGCSEECQCVQPHTQSC--------DKRDGSCSCKAG 676
C+ PG Y C CPP + P CV + +C D D +CS + G
Sbjct: 1502 CVNTPGSY--IC--DCPPDFELNP---TRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIG 1554
Query: 677 FRGERCQAECELG-YFGPGCWQAC----------TCPVGVA---------------CDSV 710
+ C LG +G C + C CP G C +
Sbjct: 1555 VGVSKASCCCSLGKAWGTPC-EMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQEL 1613
Query: 711 SGEC-GKRCPAGFQGEDCGQECPVGTF---------GVN-CSSSCSCGGAPCHGVTGQ-- 757
G C G +C F C CP G + VN C + CG C+ G
Sbjct: 1614 PGLCQGGKCINTFGSFQC--RCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYT 1671
Query: 758 CRCPPGRTGEDCEADCPEGR-------------------------------------WGL 780
C CPP + +C + R W
Sbjct: 1672 CICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNK 1731
Query: 781 GCQEICP---ACQHAARC---------DPETG------ACLCLPG---------FVGS-R 812
C++ CP + A C D TG C +PG VGS R
Sbjct: 1732 PCEQ-CPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFR 1790
Query: 813 CQDVCPAGWY----------------GPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSC 856
C+ CP G++ GP CQ C N + C C PG+ F+
Sbjct: 1791 CE--CPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSY----RCDCKPGYR-FTS 1843
Query: 857 QRACDTGHWGPDCSHPCNCSAGHGSC-DAI-SGLCLCEAGYVGPRCEQQCPQGHFGPGCE 914
C+ + + + C+ HG C D + S CLC G+ + C + CE
Sbjct: 1844 TGQCNDRNECQEIPNICS----HGQCIDTVGSFYCLCHTGFKTNDDQTMCLDIN---ECE 1896
Query: 915 QRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFF---GLDCRSACNCTAGAACDAV 971
R C +G C + G+ C C GF DC C +G
Sbjct: 1897 -RDACGNG-TCRNTIGSFNC-----------RCNHGFILSHNNDCIDVDECASGNGNLCR 1943
Query: 972 NGSCLCPAGRRGPRCAETCPAHTYGHNCSQACAC-FNGASCDPVHGQCHCAPGWMGPSCL 1030
NG C+ G +C E G C C C P G C G S
Sbjct: 1944 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP--GTCQNLDG----SYR 1997
Query: 1031 QACPAG--LYGDNCRHSCLCQNG------GTCDPVSG--HCACPEGWAGLACEKECLPRD 1080
CP G L + C C GTC G C CPEG++ + + C +D
Sbjct: 1998 CICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRC--QD 2055
Query: 1081 VRAGCRHSGGCLNGGLCDPHTGR------CLCP---AGWTGDKCQSPCLRGWFGEACAQR 1131
+R ++ GG C R C C GW GD C+ EA Q
Sbjct: 2056 LRMSYCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGW-GDPCELCPTEP--DEAFRQI 2110
Query: 1132 C------------------SCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSF--GEDC 1171
C C C H G C G CE CP G G +C
Sbjct: 2111 CPYGSGIIVGPDDSAVDMDECKEPDVCKH--GQCINTDG--SYRCE--CPFGYILAGNEC 2164
Query: 1172 AQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGC-----LNGGS 1226
+C NP GTC G +C++ PG CE + C L
Sbjct: 2165 VDTDECSVGNPC---GNGTCKNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLCAFR 2220
Query: 1227 CDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT--CLCPPG 1282
C G+ C+CP G++ + C H C Q C + GT C+C PG
Sbjct: 2221 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQ-MECKNLIGTYMCICGPG 2279
Query: 1283 ------------------RAGVRCERGCPQNRFGVGCEHTCSCRNG-------------- 1310
+ G+ CE G N G +TC C +G
Sbjct: 2280 YQRRPDGEGCVDENECQTKPGI-CENGRCLNTRG---SYTCECNDGFTASPNQDECLDNR 2335
Query: 1311 -GLCH-----------------ASNGSCSC--GLGWTGRHCELA-----------CPPGR 1339
G C + C C G GW G HCE+ CP GR
Sbjct: 2336 EGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGW-GPHCEICPFQGTVAFKKLCPHGR 2394
Query: 1340 ---YGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWC-QH 1395
A EC ++ C G C G Y C+ P G C L C Q
Sbjct: 2395 GFMTNGADIDECKVIHD-VCR--NGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQA 2451
Query: 1396 GAPCDPI------SGRCLCPAGF----HGHFCERGCEPGSFGEGCHQRC----------- 1434
PC+ I S +C CP G+ G C+ E + C C
Sbjct: 2452 PKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKC 2511
Query: 1435 ---------DCDGGAPCDPVTGLC----LCPPGRSGATCNLDCRRG----QFGPSCTLHC 1477
C C LC +C TC +C+RG Q G SC
Sbjct: 2512 PPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC--ECQRGFSLDQTGSSCEDVD 2569
Query: 1478 DCGGGADC-----DPVSG-QCHCVDGYM 1499
+C G C + + G +C C GY+
Sbjct: 2570 ECEGNHRCQHGCQNIIGGYRCSCPQGYL 2597
Score = 284 bits (726), Expect = 5e-76
Identities = 395/1582 (24%), Positives = 552/1582 (34%), Gaps = 333/1582 (21%)
Query: 132 LCFHGGRCVP--GSAQPCHCPPGFQ---GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCE 186
LC GRC+P GS + C C GFQ C DVDEC N C+N GSY C+
Sbjct: 459 LC-QNGRCIPTPGSCR-CECNKGFQLDLRGEC-IDVDECEK-NPCAGGECINNQGSYTCQ 514
Query: 187 CKPGFRLHTDSRTCLAINSCALGNGGCQH-HCVQLTITRHRCQCRPGFQLQEDGRHCVRR 245
C+ G++ C I+ C C + C+ + H C C GF + DG++C
Sbjct: 515 CRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFH-CVCNAGFHVTRDGKNCEDM 573
Query: 246 SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQ 304
C+ RN C G +C C G+QLA+DG+ C+D++EC C +G C+NT
Sbjct: 574 DECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETP-GICMNGRCVNTD 632
Query: 305 GSFKCVCHAGYELGADGRQCYRIEM----------------------------------- 329
GS++C C G +G DGR C M
Sbjct: 633 GSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAF 692
Query: 330 -EIVNSCEANNGG-----CSHGCSHTSAGP------------------------LCTCPR 359
E C A N CS G TSAG C C
Sbjct: 693 GEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNS 752
Query: 360 GYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 417
GYE+D+ + C+D+++C + C C N PG + C C G+ D CED+DEC
Sbjct: 753 GYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECE 812
Query: 418 SSRGGCEHH-CTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAV 476
SS C + C N GSF C C + L + C I
Sbjct: 813 SS--PCINGVCKNSPGSFICECSSESTLDPTKTIC----------------------IET 848
Query: 477 LQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDD--CRNG---- 530
++ Q D E + G ++ L ++G C+L D C G
Sbjct: 849 IKGTCWQTVIDGRC-----EININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRI 903
Query: 531 -GTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGV 589
GT +D C+ G +C +T G SF C C +G T D+
Sbjct: 904 KGTQCEDIDECEVFPG----VCKNGLCVNTRG---SFKCQCPSGMTLDA----------- 945
Query: 590 SGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPG 649
+G C D + + ++ ++C GR HR+ AC C G A+G
Sbjct: 946 TGRICLDIRLETCFLRYEDEECTLPIAGR-HRM-DACCCSVGA------------AWGTE 991
Query: 650 CSEEC--QCVQPHTQSCDKRDGSC-----SCKAGFRG-ERCQAECELGYFGP-----GCW 696
EEC + + + C + G + K F+ C+ L G G +
Sbjct: 992 ECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSF 1051
Query: 697 QACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFG-----------------VN 739
+ C C G A DS C + CG+ V T G N
Sbjct: 1052 K-CRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKN 1110
Query: 740 CS--SSCS-----CGGAPCHGVTG--QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQ 790
C C C G CH G +C CPPG + C + +CP
Sbjct: 1111 CMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCP--- 1167
Query: 791 HAARCDPETG--ACLCLPGFVGSR----CQDVCPAGWYGPSCQTRCSCANDGHCHPATGH 844
RC G C C PG+ + C D+ C+T C+ + +
Sbjct: 1168 -NGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSY------E 1220
Query: 845 CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQ 902
CSC PG+ QR+C +C N G G C I G CLC G++ +
Sbjct: 1221 CSCQPGFALMPDQRSCTD---IDECEDNPNICDG-GQCTNIPGEYRCLCYDGFMASEDMK 1276
Query: 903 QCPQGHFGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCR-SA 959
C + C+ C++ G+ C C G+ G + C +C A
Sbjct: 1277 TCVDVN---ECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTD---INECEIGA 1330
Query: 960 CNCTAGAACDAVNGS--CLCPAG--RRGPRCAETCPAHTYGHNCSQACACFNGASCDPVH 1015
NC A C GS C C G G +C + H CSQ C N
Sbjct: 1331 HNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMG----S 1386
Query: 1016 GQCHCAPGWMGP--SCLQACPAGLYGDNCRHSC-LCQNGGTCDPVSGH-CACPEGWAGLA 1071
+C C G+ G +C D C + LC NG + G+ C C G+ A
Sbjct: 1387 YRCLCKEGYTGDGFTCTDL-------DECSENLNLCGNGQCLNAPGGYRCECDMGFVPSA 1439
Query: 1072 CEKECLPRDVRAGCRHSGGCLNGGLCD-PHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQ 1130
K C D C C+ G + P RC C G+ D+ C C
Sbjct: 1440 DGKACEDID---ECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD---VNECLD 1493
Query: 1131 RCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGEN--PACHP 1186
+C G C + G+ C CPP F + C G +C + G+N AC
Sbjct: 1494 PTTCISG-NCVNTPGSYICDCPPDFELNPTRVGCVDTRSG-NCYLDIRPRGDNGDTACSN 1551
Query: 1187 ATG------TCSCAAGYHGPSCQQRCP-----------PGRYG-------------PGCE 1216
G +C C+ G + + CP PG G C+
Sbjct: 1552 EIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQ 1611
Query: 1217 QLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVT 1274
+L G GG C G+ CRCPTG+ + C C CG G + V
Sbjct: 1612 ELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVN---ECETPGICGPGTCYNTVG 1668
Query: 1275 G-TCLCPPGRAGVRCERGCPQNRFGVGCEH----TCSCRNGGLCHASNGSCSC----GLG 1325
TC+CPP V C R + + +C L + + C C G
Sbjct: 1669 NYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRA 1728
Query: 1326 WTGRHCELACPPGRYGAACHLECSCHNNSTCEPATG------TCRCGPGFYGQACEH--- 1376
W + CE CP L S + TG CR PG CE+
Sbjct: 1729 W-NKPCE-QCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPG----VCENGVC 1782
Query: 1377 ---------PCPPGFHGAG----CQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEP 1423
CP GF C+ + CQ+G C + C+ AG + C+ G
Sbjct: 1783 INMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQR-NAECINTAGSYRCDCKPGYRF 1841
Query: 1424 GSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSC--TLHCD--- 1478
S G+ C+ R +C P G C+ G C+ + C C+
Sbjct: 1842 TSTGQ-CNDRNECQ-EIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA 1899
Query: 1479 CGGGADCDPV-SGQCHCVDGYM 1499
CG G + + S C C G++
Sbjct: 1900 CGNGTCRNTIGSFNCRCNHGFI 1921
Score = 264 bits (675), Expect = 4e-70
Identities = 378/1542 (24%), Positives = 525/1542 (34%), Gaps = 333/1542 (21%)
Query: 102 TEARTVLRCCRGWMQQPDEEGCLS---AECSASLCFHGGRCVPGSAQ-PCHCPPGF--QG 155
T+ + C G+ + + GC E A C C + C C PG+ G
Sbjct: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDG 1358
Query: 156 PRCQYDVDECRTHNGGC-QHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCA-----L 208
+C D+DEC C QH C NT GSY C CK G+ D TC ++ C+
Sbjct: 1359 IKCT-DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLC 1415
Query: 209 GNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARC 268
GNG C + +RC+C GF DG+ C C+ N C + GL RC
Sbjct: 1416 GNGQCLN-----APGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRC 1470
Query: 269 ECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELG------ADGR 322
EC +GY+L G C DV+EC + C+NT GS+ C C +EL D R
Sbjct: 1471 ECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTR 1530
Query: 323 --QCYRIEMEIVNSCEANNGGCSH--GCSHTSAGPLCT---------------------- 356
CY ++I + + CS+ G + A C+
Sbjct: 1531 SGNCY---LDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKI 1587
Query: 357 -CPRGYELDTDQRTCI--DVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCE 411
CP G + T I D+D+C + P C C N G ++C C GY L+ D C+
Sbjct: 1588 LCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCD 1647
Query: 412 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMV---------DLD 462
DV+EC + C N G++ C C Y C + + D
Sbjct: 1648 DVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD 1707
Query: 463 GELPFVRPLPHIAVLQDELPQLF----QDDDVGADEEEAELRGEHTLTEKFVCLDDSFGH 518
GEL F + + + + + + + +E A L G FV +D G
Sbjct: 1708 GELLF-NMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQ--RPGFV-IDIYTG- 1762
Query: 519 DCSLTCDDCR------NGGTC--LLGLDGCDCPEGW----TGLICNETCPPDTFGKNCSF 566
+ D+CR G C ++G C+CP G+ L+C + C
Sbjct: 1763 -LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDI-------DECQN 1814
Query: 567 SCSCQNGGTCDSVTGA--CRCPPGVSGTN---CEDGCPKGYYGKHCRKKCNCANRGRCHR 621
CQ C + G+ C C PG T+ C D C++ N + G+C
Sbjct: 1815 GPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCND-------RNECQEIPNICSHGQCID 1867
Query: 622 LYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGF 677
G+ CLC G C EC+ +C GS C C GF
Sbjct: 1868 TVGSFYCLCHTGFKTNDDQTMCLD-------INECERDACGNGTCRNTIGSFNCRCNHGF 1920
Query: 678 RGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFG 737
++ G C C + G +C G++ G+ C
Sbjct: 1921 ILSHNNDCIDVDECASGNGNLCR---NGQCINTVGSFQCQCNEGYEVAPDGRTCV--DIN 1975
Query: 738 VNCSSSCSCGGAPCHGVTG--QCRCPPGRT--GEDCE--ADCPEGRWGLGCQEICPACQH 791
C C + G +C CPPG + E CE +C E EIC
Sbjct: 1976 ECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEE------PEICA---- 2025
Query: 792 AARCDPETGA--CLCLPGF----VGSRCQDV----CPAGWYGPSCQT---------RCSC 832
C G+ CLC GF G RCQD+ C A + G C + C C
Sbjct: 2026 LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 2085
Query: 833 A--NDGHCHPATGHCSCAPGWTGFSCQRACDTGHW---GPD--------CSHPCNCSAGH 879
A +G P C P + ++ C G GPD C P C H
Sbjct: 2086 ALKGEGWGDP----CELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCK--H 2139
Query: 880 GSCDAISGLCLCEAGYVGPRCEQQCPQGHF--GPGCEQRCQCQHG-----AACDHVSGA- 931
G C G CE CP G+ G C +C G C +V G
Sbjct: 2140 GQCINTDGSYRCE-----------CPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGF 2188
Query: 932 -CTCPAGWRG---TFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAG---RRGP 984
CTC G+ CE L C C T G+ C CP G R
Sbjct: 2189 ECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSY------ECKCPVGYVLREDR 2242
Query: 985 R-CAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDN 1041
R C + H+C++ C + G C C PG+ + C + +
Sbjct: 2243 RMCKDEDECEEGKHDCTE-----KQMECKNLIGTYMCICGPGYQRRPDGEGC---VDENE 2294
Query: 1042 CR-HSCLCQNGGTCDPVSGH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDP 1099
C+ +C+NG + + C C +G+ + ECL G C
Sbjct: 2295 CQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDN-------------REGYCFT 2341
Query: 1100 HTGRCLCPAG------WTGDKCQSPCLRGW--------FGEACAQRCSCPPGAA------ 1139
+ +C G T +C RGW F A + CP G
Sbjct: 2342 EVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA 2401
Query: 1140 ----CHHVTGACRCPPGFTGSG-----CEQACPPGSFGEDCAQMCQCPGENPACH----- 1185
C + CR G C+ P G C + +C C+
Sbjct: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKN 2461
Query: 1186 -PATGTCSCAAGY----HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGF 1240
+ CSC GY G SC+ C+ LC GG C+CP GF
Sbjct: 2462 TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGF------TCKCPPGF 2515
Query: 1241 LGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVG 1300
T + +C + ++CG G C PG C+RG ++ G
Sbjct: 2516 --TQHHTSCIDNNECTSDINLCGS---------KGICQNTPGSFTCECQRGFSLDQTGSS 2564
Query: 1301 CEHTCSCRNGGLCH------ASNGSCSCGLGWTGRHCELACPPGRYGAACHL--ECSCHN 1352
CE C C CSC G+ + C + H+ SCHN
Sbjct: 2565 CEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHN 2624
Query: 1353 NSTCEPATGTCRCGPGFYGQACEHPCPPGFH----GAGCQGLCWCQHGAPCDPISGRCLC 1408
G+ +C CP GF GCQ + C G+ P S C
Sbjct: 2625 ------TLGSYKC-----------MCPAGFQYEQFSGGCQDINEC--GSAQAPCSYGCSN 2665
Query: 1409 PAGFHGHFCERGCEPGSF--GEG-CHQRCDCDGGAPCDPVTG 1447
G G+ C GC PG F G+G C G P PV+G
Sbjct: 2666 TEG--GYLC--GCPPGYFRIGQGHCVSGMGMGRGNPEPPVSG 2703
Score = 261 bits (666), Expect = 5e-69
Identities = 395/1645 (24%), Positives = 559/1645 (33%), Gaps = 349/1645 (21%)
Query: 71 PVWKAGCGWQAWCVGHERRTVYYMGY------RQVYTTEARTVL--RCCRGWMQQPDEEG 122
PV ++GC CV R Y G+ R T TV+ + C+G Q
Sbjct: 148 PVCESGCLNGGRCVAPNRCACTY-GFTGPQCERDYRTGPCFTVISNQMCQG---QLSGIV 203
Query: 123 CLSAECSASLCFHGGR-CVPGSAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQH-RC 176
C C A++ G C AQP C GF + CQ DVDEC+ G CQ C
Sbjct: 204 CTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQ-DVDECQAIPGLCQGGNC 262
Query: 177 VNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQ 236
+NT GS+ C+C G +L+ S+ C I+ C+ G C+ T++ + C+C PGF
Sbjct: 263 INTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTS 322
Query: 237 EDGRHCVRRSP----CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-AA 291
DG C+ P A NG C + Q+ + + + +C C D C +
Sbjct: 323 PDGTRCIDVRPGYCYTALTNGRCSN--QLPQSITKMQC------------CCDAGRCWSP 368
Query: 292 GLAQCAHGC-LNTQGSFKCVCHA--------------------------GYELGAD---- 320
G+ C + F +C G+ G
Sbjct: 369 GVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVP 428
Query: 321 ---------GRQCYRI-EMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRT 369
R+ R+ + + + C+ C +G C T C C +G++LD +
Sbjct: 429 RPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDL-RGE 487
Query: 370 CIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCT 428
CIDVD+C +PC C NN G Y C C AGY+ + C D+DEC + C + C
Sbjct: 488 CIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCI 547
Query: 429 NLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVD---LDGELPFVRPLPHIAVLQDELPQLF 485
N GSF C C AG+ + D + C ++E + L+G + + QL
Sbjct: 548 NTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMC--INEDGSFKCICKPGFQLA 605
Query: 486 QDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDC---------SLTCDDCRNGGTCLLG 536
D D E E G + + V D S+ +C C D TC G
Sbjct: 606 SDGRYCKDINECETPG-ICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGG 664
Query: 537 LDGCDCPEGWTGLIC-NETCPPDT---FGKNCSFSCSCQNG----GTCDSVTGACR---- 584
C + G + +E C T FG+ C C QN C S G
Sbjct: 665 YKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQ-PCPAQNSAEYQALCSSGPGMTSAGSD 723
Query: 585 ----------CPPGV----SGTN---CEDGCPKGYYGKHCRKKCNC------ANRGRCHR 621
CP G+ GT C G GK+C C + G+C
Sbjct: 724 INECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRN 783
Query: 622 LYGA--CLCDPGLYGRFCHLTC------------------PPWAFGPGCSEECQ------ 655
G+ C C G + TC P +F CS E
Sbjct: 784 TPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKT 843
Query: 656 -CVQPHTQSCDKR--DGSCSCK---AGFRGERCQ-------AECELGYFGPGCWQACTCP 702
C++ +C + DG C A + + C + C L P C + +
Sbjct: 844 ICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRI 903
Query: 703 VGVACDSVS------GECGK------------RCPAGFQGEDCG---------------- 728
G C+ + G C +CP+G + G
Sbjct: 904 KGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYE 963
Query: 729 -QECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEIC- 786
+EC + G + +C C G T +C P R + E CP G G +EI
Sbjct: 964 DEECTLPIAGRHRMDACCCSVGAAWG-TEECEECPMRNTPEYEELCPRGP-GFATKEITN 1021
Query: 787 --PACQHAARCDPETGACL---CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP- 840
P + C C C +C+ C +G+ S + C+ ++ P
Sbjct: 1022 GKPFFKDINECKMIPSLCTHGKCRNTIGSFKCR--CDSGFALDSEERNCTDIDECRISPD 1079
Query: 841 --ATGHCSCAPGWTGFSCQRACDTGHWG-----PDCSHPCNCSAGHGSCDAISGLCLCEA 893
G C PG F C+ CD G+ +C C C G+C
Sbjct: 1080 LCGRGQCVNTPG--DFECK--CDEGYESGFMMMKNCMDIDECQRDPLLCR--GGVCHNTE 1133
Query: 894 GYVGPRCEQQCPQGH-FGPG---------CEQRCQCQHGAACDHVSG--ACTCPAGWRGT 941
G RCE CP GH P CE C ++ G C C G+ T
Sbjct: 1134 G--SYRCE--CPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST 1189
Query: 942 ----FCEHACPAGFFGLDCRSACNCTAGA-ACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
FC C + C + G+ C G L P R C +
Sbjct: 1190 PDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQR---SCTDI------- 1239
Query: 997 HNCSQACACFNGASCDPVHGQ--CHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC 1054
C +G C + G+ C C G+M ++ C D + CL GTC
Sbjct: 1240 DECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICL---SGTC 1296
Query: 1055 DPVSGH--CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGW 1110
+ G C C G++G + C D+ + C +C G +C C GW
Sbjct: 1297 ENTKGSFICHCDMGYSGKKGKTGC--TDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354
Query: 1111 TGD--KCQ--SPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGS 1166
GD KC C G C+Q C + C C G+TG G
Sbjct: 1355 IGDGIKCTDLDECSNG--THMCSQHADCKNTMGSYR----CLCKEGYTGDGF-------- 1400
Query: 1167 FGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGS 1226
C + +C C G C A G + C P G CE + C
Sbjct: 1401 ---TCTDLDECSENLNLC--GNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNI 1455
Query: 1227 CDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGV 1286
C G C G +C + R G NCT V C C ++G C+ PG
Sbjct: 1456 C--VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTC--ISGNCVNTPGSYIC 1511
Query: 1287 RCERGCPQNRFGVGCEHTCSCRNGGLCH------ASNGSCSC----GLGWTGRHCELACP 1336
C N VGC T S G C+ NG +C G+G + C C
Sbjct: 1512 DCPPDFELNPTRVGCVDTRS----GNCYLDIRPRGDNGDTACSNEIGVGVSKASC--CCS 1565
Query: 1337 PGR-YGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAG-CQGLCWCQ 1394
G+ +G C + C N S + C G GF +P CQ L
Sbjct: 1566 LGKAWGTPCEM-CPAVNTSEYKI---LCPGGEGFR----PNPITVILEDIDECQELPGLC 1617
Query: 1395 HGAPCDPISG--RCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVT------ 1446
G C G +C CP G++ + R C+ + +C+ C P T
Sbjct: 1618 QGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVN---------ECETPGICGPGTCYNTVG 1668
Query: 1447 -GLCLCPPG----RSGATCNLDCRR 1466
C+CPP G C +D RR
Sbjct: 1669 NYTCICPPDYMQVNGGNNC-MDMRR 1692
Score = 234 bits (598), Expect = 4e-61
Identities = 362/1442 (25%), Positives = 495/1442 (34%), Gaps = 301/1442 (20%)
Query: 147 CHCPPGFQ----GPRCQYDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCL 201
C C G++ G C D++EC ++ C + +C NTPGS++C C GF D +TC
Sbjct: 748 CICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806
Query: 202 AINSCALG---NGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVR--RSPC-------- 248
I+ C NG C++ C+C L C+ + C
Sbjct: 807 DIDECESSPCINGVCKNSPGSFI-----CECSSESTLDPTKTICIETIKGTCWQTVIDGR 861
Query: 249 --ANRNGSCMH-RCQVVRGLA------RCE----CHVGYQLAADGKACEDVDECAAGLAQ 295
N NG+ + +C G A C+ C GY G CED+DEC
Sbjct: 862 CEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFPGV 920
Query: 296 CAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIV------NSCEANNGG------- 341
C +G C+NT+GSFKC C +G L A GR C I +E C G
Sbjct: 921 CKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDAC 980
Query: 342 -CSHGCSH-TSAGPLCT----------CPRGYELDTDQRT-----CIDVDDCADSP--CC 382
CS G + T C CPRG T + T D+++C P C
Sbjct: 981 CCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCT 1040
Query: 383 QQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQCSCEAG 441
C N G ++C C +G+ L ++ C D+DEC S C C N G F+C C+ G
Sbjct: 1041 HGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEG 1100
Query: 442 YRL-HEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADE--EEAE 498
Y + C ++E D P L + E E
Sbjct: 1101 YESGFMMMKNCMDIDECQRD---------------------PLLCRGGVCHNTEGSYRCE 1139
Query: 499 LRGEHTLTEKF-VCLDDSFGHDCSLTCDDCRNGGTC-LLGLDGCDCPEGWTGLICNETCP 556
H L+ C+D ++C L+ C NG L+G C C G+ + P
Sbjct: 1140 CPPGHQLSPNISACIDI---NECELSAHLCPNGRCVNLIGKYQCACNPGY------HSTP 1190
Query: 557 PDTFGKNCSFSCSCQNGGT---CDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKC 611
F + CS NGG C + G+ C C PG + + C C
Sbjct: 1191 DRLFCVDID-ECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTD---IDECEDNP 1246
Query: 612 NCANRGRCHRLYG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH---TQSCDK 666
N + G+C + G CLC G TC EC + P+ + +C+
Sbjct: 1247 NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVD-------VNECD-LNPNICLSGTCEN 1298
Query: 667 RDGS--CSCKAGFRGERCQA------ECELGYFGPGCWQACTCPVGVACDSVSGECGKRC 718
GS C C G+ G++ + ECE+G A C C + +G C
Sbjct: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIG--------AHNCGKHAVCTNTAGSFKCSC 1350
Query: 719 PAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPGRTGEDCEADCPEG 776
G+ G+ G +C N + CS A C G +C C G TG+
Sbjct: 1351 SPGWIGD--GIKCTDLDECSNGTHMCS-QHADCKNTMGSYRCLCKEGYTGD--------- 1398
Query: 777 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWY----GPSCQTRCSC 832
G C ++ ++ C G CL PG G RC+ C G+ G +C+ C
Sbjct: 1399 --GFTCTDLDECSENLNLCG--NGQCLNAPG--GYRCE--CDMGFVPSADGKACEDIDEC 1450
Query: 833 ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCE 892
+ C G C PG C+ + G +C+ C ISG C+
Sbjct: 1451 SLPNIC--VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECL---DPTTCISGNCVNT 1505
Query: 893 AGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFF 952
G C GC D SG C RG + AC
Sbjct: 1506 PGSYICDCPPDFELNPTRVGC-----------VDTRSGNCYLDIRPRGDNGDTACSNEIG 1554
Query: 953 GLDCRSACNCTAGAA-------CDAVNGS---CLCPAGRRGPRCAETCPAHTYGHNCSQA 1002
+++C C+ G A C AVN S LCP G G R C +
Sbjct: 1555 VGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGG-EGFRPNPITVILEDIDECQEL 1613
Query: 1003 CACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGH 1060
G C G QC C G+ + C + C +C GTC G+
Sbjct: 1614 PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDD---VNECETPGIC-GPGTCYNTVGN 1669
Query: 1061 --CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPH-----TGRCLCPAGWTGD 1113
C CP + + C+ D+R + + CD T + C + G
Sbjct: 1670 YTCICPPDYMQVNGGNNCM--DMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGR 1727
Query: 1114 KCQSPCLR------GWFGEACAQRCSCPPGAACHHVTG------ACRCPPGFTGSG---- 1157
PC + F C S PG TG CR PG +G
Sbjct: 1728 AWNKPCEQCPIPSTDEFATLCG---SQRPGFVIDIYTGLPVDIDECREIPGVCENGVCIN 1784
Query: 1158 ------CEQACPPGSFGED----CAQMCQCPG-----ENPACHPATGT--CSCAAGYHGP 1200
CE CP G F D C + +C N C G+ C C GY
Sbjct: 1785 MVGSFRCE--CPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFT 1842
Query: 1201 S---CQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFG 1255
S C R C+++ + G C G+ C C TGF D C
Sbjct: 1843 STGQCNDR-------NECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMC----LD 1891
Query: 1256 PNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERG--CPQNRFGVGCEHTCSCRNGGLC 1313
N CG GTC G RC G N + + C+ NG LC
Sbjct: 1892 INECERDACG--------NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDE-CASGNGNLC 1942
Query: 1314 HASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEP---ATGTCRCGPGFY 1370
NG C +G + C G A C N EP A GTC+ G Y
Sbjct: 1943 R--NGQCINTVG----SFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSY 1996
Query: 1371 GQACEHPCPPGF--HGAGCQGLCWCQHG------APCDPISG--RCLCPAGFHGHFCERG 1420
CPPG+ C+ + C C G +CLCP GF R
Sbjct: 1997 ----RCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRR 2052
Query: 1421 CE 1422
C+
Sbjct: 2053 CQ 2054
Score = 212 bits (540), Expect = 2e-54
Identities = 385/1584 (24%), Positives = 520/1584 (32%), Gaps = 349/1584 (22%)
Query: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRC-QYDVDEC--R 166
CC GW P C+ C S C G P C CP G P C + C R
Sbjct: 67 CCPGWKTLPGGNQCIVPICRHS-CGDGFCSRPNM---CTCPSGQIAPSCGSRSIQHCNIR 122
Query: 167 THNGGCQHRCVNTPGSYLCECKPGF-RLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 225
NGG C + C C+ G+ H C S L G C + +
Sbjct: 123 CMNGGS---CSDDH----CLCQKGYIGTHCGQPVC---ESGCLNGGRC--------VAPN 164
Query: 226 RCQCRPGFQLQEDGRHCVRRSPCAN--RNGSCMHRCQ-VVRGLARCECHVGYQLAADGKA 282
RC C GF + R R PC N C + +V C VG A G
Sbjct: 165 RCACTYGFTGPQCERD-YRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVG---RAWGHP 220
Query: 283 CEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC 342
CE C A C G + + C + V+ C+A G C
Sbjct: 221 CE---MCPAQPHPCRRGFIPNIRTGAC--------------------QDVDECQAIPGLC 257
Query: 343 SHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYA 399
G C +T C CP G++L+ + C D+D+C+ P C CTN Y C C
Sbjct: 258 QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPP 317
Query: 400 GYRLSADGCGCEDVDE----CASSRGGCEHHCTNLAGSFQCSCEAG-------------- 441
G+ S DG C DV A + G C + QC C+AG
Sbjct: 318 GFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMC 377
Query: 442 -YRLHED-RRGCS-PL------EEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGA 492
R ED + CS P+ E P L G +P V P+P P +
Sbjct: 378 PIRATEDFNKLCSVPMVIPGRPEYPPPPL-GPIPPVLPVP---------PGFPPGPQIPV 427
Query: 493 DEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCL--LGLDGCDCPEGWTGLI 550
E + E L + C L C+N G C+ G C+C +G+ +
Sbjct: 428 PRPPVEYL--YPSREPPRVLPVNVTDYCQLVRYLCQN-GRCIPTPGSCRCECNKGFQLDL 484
Query: 551 CNETCPPDTFGKNCSFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCR 608
E D KN C+ GG C + G+ C+C G T C C
Sbjct: 485 RGECIDVDECEKN---PCA---GGECINNQGSYTCQCRAGYQSTLTRTECRD---IDECL 535
Query: 609 KKCNCANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH---TQS 663
+ N GRC G+ C+C+ G H+T G C + +C +
Sbjct: 536 QNGRICNNGRCINTDGSFHCVCNAGF-----HVT----RDGKNCEDMDECSIRNMCLNGM 586
Query: 664 CDKRDGS--CSCKAGFR----GERCQ--AECELGYFGPGCWQACTCPVGVACD-SVSGEC 714
C DGS C CK GF+ G C+ ECE PG C V D S EC
Sbjct: 587 CINEDGSFKCICKPGFQLASDGRYCKDINECET----PGICMNGRC---VNTDGSYRCEC 639
Query: 715 GKRCPAGFQGEDCGQ--------------ECPVGTFGVNCSSSCSCG------GAPCHGV 754
G G C +C FG S C C G PC
Sbjct: 640 FPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPC 699
Query: 755 TGQ--------CRCPPGRTG-----EDCEAD---CPEGRWGLGCQEICPACQHAARCDPE 798
Q C PG T +C D CP G IC +
Sbjct: 700 PAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNG--------ICENLR-------G 744
Query: 799 TGACLCLPGF----VGSRCQDVCPAGWYGPSCQTRCSCANDGHCH--PATGHCSCAPGWT 852
T C+C G+ G C D+ C ++G C P + C+C G+
Sbjct: 745 TYKCICNSGYEVDSTGKNCVDI-------NECVLNSLLCDNGQCRNTPGSFVCTCPKGFI 797
Query: 853 GFSCQRAC---DTGHWGPDCSHPCNCSAGHGSC--------DAISGLCL------CEAGY 895
+ C D P + C S G C D +C+ C
Sbjct: 798 YKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV 857
Query: 896 VGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGW---RGTFCEHACPAGFF 952
+ RCE C G+ C C G+ +GT CE F
Sbjct: 858 IDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVF 917
Query: 953 GLDCRSA----------CNCTAGAACDAVNGSCLCPAGRRGPRC-----AETCPAHTYGH 997
C++ C C +G DA CL R C E C G
Sbjct: 918 PGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICL---DIRLETCFLRYEDEECTLPIAGR 974
Query: 998 NCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAG-------------LYGD--NC 1042
+ AC C GA+ +C P P + CP G + D C
Sbjct: 975 HRMDACCCSVGAAWGT--EECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINEC 1032
Query: 1043 RH-SCLCQNGGTCDPV-SGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLC--D 1098
+ LC +G + + S C C G+A + E+ C D CR S G C
Sbjct: 1033 KMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDID---ECRISPDLCGRGQCVNT 1089
Query: 1099 PHTGRCLCPAGW-TGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTG 1155
P C C G+ +G C+ + C + G CH+ G+ C CPPG
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMD---IDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
Query: 1156 SGCEQACPPGSFGEDCAQMCQCPGENPACHPATG--TCSCAAGYHGPSCQQRCPPGRYGP 1213
S AC + E A +C N C G C+C GYH P R
Sbjct: 1147 SPNISACIDINECELSAHLC----PNGRCVNLIGKYQCACNPGYHS-------TPDRLFC 1195
Query: 1214 GCEQLCGCLNGGS---CDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGA 1268
C +NGG C + G+ C C GF +C + ++C GQ
Sbjct: 1196 VDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQ-- 1253
Query: 1269 ACDPVTG--TCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGS--CSCGL 1324
C + G CLC G + C C+ + G C + GS C C +
Sbjct: 1254 -CTNIPGEYRCLCYDGFMASEDMKTCVDVN---ECDLNPNICLSGTCENTKGSFICHCDM 1309
Query: 1325 GWTGRHCELACPPGRYGAACHLEC-----SCHNNSTCEPATGT--CRCGPGFYGQACE-- 1375
G++G+ G+ G EC +C ++ C G+ C C PG+ G +
Sbjct: 1310 GYSGK-------KGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCT 1362
Query: 1376 --HPCPPGFH----GAGCQGL-----CWCQHGAPCDPI----------------SGRCLC 1408
C G H A C+ C C+ G D +G+CL
Sbjct: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLN 1422
Query: 1409 PAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQ 1468
G + C+ G P + G+ C +C C V G C PG C + +
Sbjct: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNIC--VFGTCHNLPGLFRCECEIGYELDR 1480
Query: 1469 FGPSCTLHCDCGGGADCDPVSGQC 1492
G +CT +C C +SG C
Sbjct: 1481 SGGNCTDVNECLDPTTC--ISGNC 1502
Score = 157 bits (398), Expect = 6e-38
Identities = 280/1208 (23%), Positives = 389/1208 (32%), Gaps = 261/1208 (21%)
Query: 414 DECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLP 472
D C R C++ C GS +C C G++L DL GE
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQL---------------DLRGECI------ 489
Query: 473 HIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGT 532
DV E+ GE + G+ +LT +CR+
Sbjct: 490 ----------------DVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDE 533
Query: 533 CLLGLDGCD---C--PEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPP 587
CL C+ C +G +CN GKNC C C + G C
Sbjct: 534 CLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC--LNGMCINED 591
Query: 588 GVSGTNCEDGCPKGYYGKHCRKKCNCAN-----RGRCHRLYGA--CLCDPGLY----GRF 636
G C+ G G++C+ C GRC G+ C C PGL GR
Sbjct: 592 GSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRV 651
Query: 637 C---HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQ-------AEC 686
C H+ + G + QC++P + K + C+ GE CQ AE
Sbjct: 652 CVDTHMRSTCY----GGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEY 707
Query: 687 E-LGYFGPGCWQACT-----------CPVGVACDSVSGECGKRCPAGFQGEDCGQECPVG 734
+ L GPG A + CP G+ C+++ G C +G++ + G+ C
Sbjct: 708 QALCSSGPGMTSAGSDINECALDPDICPNGI-CENLRGTYKCICNSGYEVDSTGKNCV-- 764
Query: 735 TFGVNCSSSCSCGGAPCHGVTGQ--CRCPPG-------RTGED---CEAD-CPEGRWGLG 781
+S C C G C CP G +T ED CE+ C G
Sbjct: 765 DINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNS 824
Query: 782 CQEICPACQHAARCDPETGACL------CLPGFVGSRCQDVCPAGWYGPSCQTRCSCAND 835
C + DP C+ C + RC+ C + A
Sbjct: 825 PGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWG 884
Query: 836 GHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGY 895
C C G++ G C C G C +GLC+ G
Sbjct: 885 SPCTLCQVDPICGKGYSRIK----------GTQCEDIDECEVFPGVCK--NGLCVNTRGS 932
Query: 896 VGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGAC------TCPAGWRGTFCEHACPA 949
+CQC G D C TC + + C
Sbjct: 933 F-------------------KCQCPSGMTLDATGRICLDIRLETCFLRYE----DEECTL 969
Query: 950 GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAH--------TYG----- 996
G AC C+ GAA CP R P E CP T G
Sbjct: 970 PIAGRHRMDACCCSVGAAWGTEECE-ECPM-RNTPEYEELCPRGPGFATKEITNGKPFFK 1027
Query: 997 --HNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGG 1052
+ C + C G +C C G+ S + C D CR S G
Sbjct: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDI---DECRISPDLCGRG 1084
Query: 1053 TCDPVSG--HCACPEGW-AGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCP 1107
C G C C EG+ +G K C+ D C+ GG+C G RC CP
Sbjct: 1085 QCVNTPGDFECKCDEGYESGFMMMKNCMDIDE---CQRDPLLCRGGVCHNTEGSYRCECP 1141
Query: 1108 AGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPG 1165
G S C+ E A C P C ++ G C C PG+ + P
Sbjct: 1142 PGHQLSPNISACIDINECELSAHLC---PNGRCVNLIGKYQCACNPGY------HSTPDR 1192
Query: 1166 SFGEDCAQMCQCPGENPACHP------ATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLC 1219
F C + +C N C + CSC G+ Q+ C CE
Sbjct: 1193 LF---CVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDI---DECEDNP 1246
Query: 1220 GCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT- 1276
+GG C G C C GF+ ++ TC ++C G C+ G+
Sbjct: 1247 NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG---TCENTKGSF 1303
Query: 1277 -CLCPPGRAGVRCERGCPQ-NRFGVGCEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCE 1332
C C G +G + + GC N +G + C +C + GS CSC GW G +
Sbjct: 1304 ICHCDMGYSGKKGKTGCTDINECEIGAHN---CGKHAVCTNTAGSFKCSCSPGWIGDGIK 1360
Query: 1333 LA----CPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAG-- 1386
C G + C ++ C+ G+ RC C G+ G G
Sbjct: 1361 CTDLDECSNGTH--------MCSQHADCKNTMGSYRC-----------LCKEGYTGDGFT 1401
Query: 1387 CQGLCWCQHGAP-CDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPV 1445
C L C C +G+CL G + C+ G P + G+ C +C C V
Sbjct: 1402 CTDLDECSENLNLCG--NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNIC--V 1457
Query: 1446 TGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGP-TCR 1504
G C PG C+C G + D G C V+ + P TC
Sbjct: 1458 FGTCHNLPG-------------------LFRCECEIGYELDRSGGNCTDVNECLDPTTCI 1498
Query: 1505 EGGPLRLP 1512
G + P
Sbjct: 1499 SGNCVNTP 1506
Score = 108 bits (271), Expect = 3e-23
Identities = 181/743 (24%), Positives = 234/743 (31%), Gaps = 153/743 (20%)
Query: 806 PGFVGSRCQDVCPAGWYG---------PSCQTRCSCANDGHCHPATGHCSCAPGWTGFSC 856
P GSR C GW P C+ C DG C C+C G SC
Sbjct: 56 PNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCG---DGFCS-RPNMCTCPSGQIAPSC 111
Query: 857 QRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR 916
H C + +CS H CLC+ GY+G C Q P CE
Sbjct: 112 GSR-SIQHCNIRCMNGGSCSDDH---------CLCQKGYIGTHCGQ--------PVCES- 152
Query: 917 CQCQHGAACDHVSGACTCPAGWRGTFCEHACPAG--FFGLDCRSACNCTAGAACDAVNGS 974
C +G C C C G+ G CE G F + + +G C
Sbjct: 153 -GCLNGGRC-VAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC--TKTL 208
Query: 975 CLCPAGRRGPRCAETCPAHTYGHNCSQAC-------ACFNGASCDPVHGQCHCAPGWMGP 1027
C GR E CPA H C + AC + C + G C G
Sbjct: 209 CCATVGRAWGHPCEMCPAQP--HPCRRGFIPNIRTGACQDVDECQAIPGLC------QGG 260
Query: 1028 SCLQA-------CPAGLYGDNCRHSC-----------LCQNGGTCDPVSGH-CACPEGWA 1068
+C+ CPAG + C +C+ G + VS + C CP G+
Sbjct: 261 NCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFY 320
Query: 1069 GLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG------RCLCPAGWTGDKCQSPCLRG 1122
C+ DVR G ++ L G C +C C AG +C SP +
Sbjct: 321 TSPDGTRCI--DVRPGYCYT--ALTNGRCSNQLPQSITKMQCCCDAG----RCWSPGV-- 370
Query: 1123 WFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENP 1182
+ C P A C P G PP G + PG P
Sbjct: 371 ---TVAPEMC---PIRATEDFNKLCSVPMVIPG---RPEYPPPPLGPIPPVLPVPPGFPP 421
Query: 1183 ACHPATGTCSCAAGYHGPSCQ-QRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
P Y PS + R P C+ + G C G+CRC
Sbjct: 422 G--PQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRC----- 474
Query: 1242 GTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGC 1301
+CN G C V C + G C+ G +C G C
Sbjct: 475 --ECNKGFQLDLRG-ECIDVDECEKNPCAG---GECINNQGSYTCQCRAGYQSTLTRTEC 528
Query: 1302 EHTCSC-RNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACH--LECSCHN---NST 1355
C +NG +C +NG C G C R G C ECS N N
Sbjct: 529 RDIDECLQNGRIC--NNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM 586
Query: 1356 CEPATGTCRCGPGFYGQACEHPCPPGFH----GAGCQGLCWCQHGAPCDPISGRCLCPAG 1411
C G+ +C C PGF G C+ + C+ C ++GRC+ G
Sbjct: 587 CINEDGSFKC-----------ICKPGFQLASDGRYCKDINECETPGIC--MNGRCVNTDG 633
Query: 1412 FHGHFCERGCEPGSFGEGC---HQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQ 1468
+ C G G G C H R C GG G C+ P GA +C
Sbjct: 634 SYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYK----RGQCIKP--LFGAVTKSEC---- 683
Query: 1469 FGPSCTLHCDCGGGADCDPVSGQ 1491
C + G C P Q
Sbjct: 684 ----CCASTEYAFGEPCQPCPAQ 702
Score = 105 bits (261), Expect = 4e-22
Identities = 226/1009 (22%), Positives = 315/1009 (31%), Gaps = 214/1009 (21%)
Query: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643
R PP V N D C Y C N GRC G+C C+ C+
Sbjct: 439 REPPRVLPVNVTDYCQLVRY--------LCQN-GRCIPTPGSCRCE-------CNKGFQL 482
Query: 644 WAFGPGCS-EECQCVQPHTQSCDKRDGS--CSCKAGFRGERCQAECELGYFGPGCWQACT 700
G +EC+ C GS C C+AG++ + EC C Q
Sbjct: 483 DLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECR---DIDECLQNGR 539
Query: 701 CPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QC 758
C + G C AGF G+ C CS C C G +C
Sbjct: 540 ICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD---ECSIRNMCLNGMCINEDGSFKC 596
Query: 759 RCPPG----RTGEDC----EADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPG--F 808
C PG G C E + P G+ C + RC+ G + L G
Sbjct: 597 ICKPGFQLASDGRYCKDINECETP----GICMNGRCVNTDGSYRCECFPGLAVGLDGRVC 652
Query: 809 VGSRCQDVCPAGW---------YGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRA 859
V + + C G+ +G ++ C CA+ + C P Q
Sbjct: 653 VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEP--CQPCPAQNSAEYQAL 710
Query: 860 CDTGHWGPDCSHPCN-CS-----AGHGSCDAISGL--CLCEAGYVGPRCEQQCPQGHFGP 911
C +G N C+ +G C+ + G C+C +GY + C
Sbjct: 711 CSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD--INE 768
Query: 912 GCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACD 969
C +G C + G+ CTCP G+ + D ++ + +
Sbjct: 769 CVLNSLLCDNG-QCRNTPGSFVCTCPKGF------------IYKPDLKTCEDIDECESSP 815
Query: 970 AVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQC-HCAPGWMGPS 1028
+NG C G S C C + ++ DP C G +
Sbjct: 816 CINGVCKNSPG-------------------SFICECSSESTLDPTKTICIETIKGTCWQT 856
Query: 1029 CLQA-CPAGLYGDNCRHSCLCQN-----GGTCDPVSGHCACPEGWA---GLACEKECLPR 1079
+ C + G + C C + G C C +G++ G CE
Sbjct: 857 VIDGRCEININGATLKSQC-CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE------ 909
Query: 1080 DVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRC---SC 1134
D+ C G GLC G +C CP+G T D CL E C R C
Sbjct: 910 DIDE-CEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRL-ETCFLRYEDEEC 967
Query: 1135 PPGAACHHVTGACRCPPGFTGSGCEQACPPGSFG-EDCAQMCQCPGENPACHPATGTCSC 1193
A H AC C G ++G E+C +CP N + C
Sbjct: 968 TLPIAGRHRMDACCCSVG------------AAWGTEECE---ECPMRNTPEYEE--LCPR 1010
Query: 1194 AAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTC-- 1249
G+ P + C+ + G C G+ CRC +GF C
Sbjct: 1011 GPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD 1070
Query: 1250 -PQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGV-GCEHTCSC 1307
+ R P+ +CG GQ C+ PG +C+ G + C C
Sbjct: 1071 IDECRISPD---LCGRGQ----------CVNTPGDFECKCDEGYESGFMMMKNCMDIDEC 1117
Query: 1308 R------NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGA----------ACHLECSCH 1351
+ GG+CH + GS C CPPG + C L
Sbjct: 1118 QRDPLLCRGGVCHNTEGSYRC-----------ECPPGHQLSPNISACIDINECELSAHLC 1166
Query: 1352 NNSTCEPATG--TCRCGPGFYGQA----CEHPCPPGFHGAGCQGLCWCQHGAPCDPISGR 1405
N C G C C PG++ C GC+ C G S
Sbjct: 1167 PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEG------SYE 1220
Query: 1406 CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG--LCLCPPGRSGA----T 1459
C C GF +R C E CD G C + G CLC G + T
Sbjct: 1221 CSCQPGFALMPDQRSCTDIDECEDNPNICD---GGQCTNIPGEYRCLCYDGFMASEDMKT 1277
Query: 1460 CNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ--CHCVDGYMGPTCREG 1506
C +D P+ L C+ G CHC GY G + G
Sbjct: 1278 C-VDVNECDLNPNICL------SGTCENTKGSFICHCDMGYSGKKGKTG 1319
Score = 82.8 bits (203), Expect = 2e-15
Identities = 74/275 (26%), Positives = 98/275 (35%), Gaps = 53/275 (19%)
Query: 223 TRHRCQCRPGFQLQEDGRHCVR---RSPCANRNGSCMHRCQVVRGLARCEC------HVG 273
+R+ C PG++ G C+ R C + S + C G C H
Sbjct: 61 SRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCN 120
Query: 274 YQLAADGKACEDVDECAA---------GLAQCAHGCLN---TQGSFKCVCHAGYELGADG 321
+ +G +C D D C G C GCLN +C C G+ G
Sbjct: 121 IR-CMNGGSCSD-DHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFT----G 174
Query: 322 RQCYR----------------------IEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPR 359
QC R I C H C A P C R
Sbjct: 175 PQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH-PCRR 233
Query: 360 GYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 417
G+ + C DVD+C P C C N G +EC C AG++L+ CED+DEC+
Sbjct: 234 GFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECS 293
Query: 418 SSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRRGC 451
+ G CE CTN S+ C C G+ D C
Sbjct: 294 TIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328
Score = 39.7 bits (91), Expect = 0.023
Identities = 42/158 (26%), Positives = 47/158 (29%), Gaps = 41/158 (25%)
Query: 1348 CSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCL 1407
C N+ C P T G C H C GF C C
Sbjct: 59 CGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGF----------CSR-------PNMCT 101
Query: 1408 CPAGFHGHFCERGCEPGSFGEGCHQRCD--CDGGAPCDPVTGLCLCPPGRSGATCNLDCR 1465
CP+G C G Q C+ C G C CLC G G C
Sbjct: 102 CPSGQIAPSC---------GSRSIQHCNIRCMNGGSCSD--DHCLCQKGYIGTHC----- 145
Query: 1466 RGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1503
GQ P C C GG +C C G+ GP C
Sbjct: 146 -GQ--PVCESGCLNGGRC---VAPNRCACTYGFTGPQC 177
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 285 bits (728), Expect = 3e-76
Identities = 247/792 (31%), Positives = 302/792 (38%), Gaps = 210/792 (26%)
Query: 767 EDCEADC--PEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGW--- 821
E C C + G G ++ C D C C PG+ G C D A
Sbjct: 119 EQCTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPS 178
Query: 822 YGPSCQTRC--SCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGH 879
PS C C + G C G C C PG+TG SC W P C C G
Sbjct: 179 SPPSASGSCPDDCNDQGRC--VRGRCVCFPGYTGPSCG-------W-PSCPGDCQ---GR 225
Query: 880 GSCDAISGLCLCEAGYVGPRCEQQ-CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGW 938
G C + G+C+C AG+ GP C Q+ CP+ GC QR +C+ G C C G+
Sbjct: 226 GRC--VQGVCVCRAGFSGPDCSQRSCPR-----GCSQRGRCE--------GGRCVCDPGY 270
Query: 939 RGTFC-EHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC-AETCPAHTYG 996
G C +CP G C+ C+ NG C+C G G C +CP
Sbjct: 271 TGDDCGMRSCPRG-----------CSQRGRCE--NGRCVCNPGYTGEDCGVRSCP----- 312
Query: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSC-LQACPAGLYGDNCRHSCLCQNGGTCD 1055
CSQ C + G+C C PG+ G C ++CP C GG C
Sbjct: 313 RGCSQRGRCKD--------GRCVCDPGYTGEDCGTRSCPWD-----------CGEGGRC- 352
Query: 1056 PVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKC 1115
V G C C G+ G C PRD CR G C G C+C G++GD C
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRD----CRGRGRC--------EDGECICDTGYSGDDC 399
Query: 1116 QSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC-EQACPPGSFGEDCAQM 1174
+R G+ C QR C G C C PG+TG+ C +ACP DC
Sbjct: 400 G---VRSCPGD-CNQRGRCE--------DGRCVCWPGYTGTDCGSRACP-----RDCRGR 442
Query: 1175 CQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGAC 1234
+C EN G C C AGY G C R PG C G C+ +G C
Sbjct: 443 GRC--EN-------GVCVCNAGYSGEDCGVRSCPG----------DCRGRGRCE--SGRC 481
Query: 1235 RCPTGFLGTDCNL-TCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC-ERGC 1292
C G+ G DC CP +C G+G D G C+C PG G C R C
Sbjct: 482 MCWPGYTGRDCGTRACP-----GDCR-----GRGRCVD---GRCVCNPGFTGEDCGSRRC 528
Query: 1293 PQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHN 1352
P + CR GLC +G C C G++G C PG C
Sbjct: 529 PGD-----------CRGHGLC--EDGVCVCDAGYSGEDCSTRSCPG----------GCRG 565
Query: 1353 NSTCEPATGTCRCGPGFYGQAC-EHPCPP--GFHGAGCQGLCWCQHGAPCDPISGRCLCP 1409
C G C C G+ G+ C CP HG G+C C G + S R CP
Sbjct: 566 RGQC--LDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIR-TCP 622
Query: 1410 AGFHGH-FCERG---CEPGSFGEGCHQR---CDCDGGAPCDPVTGLCLCPPGRSGATCNL 1462
+ HG CE G C+PG G C R DC G C V G+CLC G G C
Sbjct: 623 SNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGYGGEDCGQ 680
Query: 1463 D----------------CRRGQF-------GPSCTLHC---DCGGGADCDPVSGQCHCVD 1496
+ CR GQ GP C + DC G +C G C C D
Sbjct: 681 EEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECH--DGSCVCKD 738
Query: 1497 GYMGPTCREGGP 1508
GY G C E P
Sbjct: 739 GYAGEDCGEEVP 750
Score = 241 bits (615), Expect = 4e-63
Identities = 225/747 (30%), Positives = 273/747 (36%), Gaps = 230/747 (30%)
Query: 671 CSCKAGFRGERCQAECELGYFGPGCWQ--------------ACTCP-------------- 702
CS F RC CE G+ GP C + +CP
Sbjct: 143 CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202
Query: 703 ------VGVAC--DSVSGECGKR---------CPAGFQGEDCGQ-ECPVGTFGVNCSSSC 744
G +C S G+C R C AGF G DC Q CP G CS
Sbjct: 203 VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRG-----CSQRG 257
Query: 745 SCGGAPCHGVTGQCRCPPGRTGEDC-EADCPEGRWGLGCQEICPACQHAARCDPETGACL 803
C G G+C C PG TG+DC CP G C RC E G C+
Sbjct: 258 RCEG-------GRCVCDPGYTGDDCGMRSCPRG------------CSQRGRC--ENGRCV 296
Query: 804 CLPGFVG---------------SRCQD---VCPAGWYGPSCQTRC---SCANDGHCHPAT 842
C PG+ G RC+D VC G+ G C TR C G C
Sbjct: 297 CNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRC--VD 354
Query: 843 GHCSCAPGWTGFSCQ-RACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRC- 900
G C C PG+TG C R C P +C G G C+ G C+C+ GY G C
Sbjct: 355 GRCVCWPGYTGEDCSTRTC-----------PRDC-RGRGRCE--DGECICDTGYSGDDCG 400
Query: 901 EQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFC-EHACPAGFFGLDCRSA 959
+ CP C QR +C+ G C C G+ GT C ACP DCR
Sbjct: 401 VRSCP-----GDCNQRGRCE--------DGRCVCWPGYTGTDCGSRACPR-----DCRGR 442
Query: 960 CNCTAGAACDAVNGSCLCPAGRRGPRC-AETCPAHTYGHNCSQACACFNGASCDPVHGQC 1018
C NG C+C AG G C +CP C C+ G+C
Sbjct: 443 GRCE--------NGVCVCNAGYSGEDCGVRSCPGD-----------CRGRGRCE--SGRC 481
Query: 1019 HCAPGWMGPSC-LQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECL 1077
C PG+ G C +ACP GD C+ G C V G C C G+ G C
Sbjct: 482 MCWPGYTGRDCGTRACP----GD-------CRGRGRC--VDGRCVCNPGFTGEDCGSRRC 528
Query: 1078 PRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWF---GEACAQRCSC 1134
P G C GLC+ G C+C AG++G+ C + G G+ RC C
Sbjct: 529 P----------GDCRGHGLCE--DGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVC 576
Query: 1135 PPGAACHHVTGACRCPPGFTGSG-CEQA---CPPGSFGEDCAQMCQCPGENPACHP---- 1186
G + G +CP + G C+ C G EDC+ + CP CH
Sbjct: 577 EDGYSGED-CGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCS-IRTCPSN---CHGRGRC 631
Query: 1187 ATGTCSCAAGYHGPSCQQR-CPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC 1245
G C C GY GP+C R CP C G C G C C G+ G DC
Sbjct: 632 EEGRCLCDPGYTGPTCATRMCP-----------ADCRGRGRC--VQGVCLCHVGYGGEDC 678
Query: 1246 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCE-RGCPQNRFGVGCEHT 1304
P P GCG C G C+C G G C + CP +
Sbjct: 679 GQEEPPASACPG-----GCGPRELCR--AGQCVCVEGFRGPDCAIQTCPGD--------- 722
Query: 1305 CSCRNGGLCHASNGSCSCGLGWTGRHC 1331
CR G CH +GSC C G+ G C
Sbjct: 723 --CRGRGECH--DGSCVCKDGYAGEDC 745
Score = 237 bits (604), Expect = 7e-62
Identities = 209/717 (29%), Positives = 275/717 (38%), Gaps = 215/717 (29%)
Query: 540 CDCPEGWTGLICNETCP---PDTFGKNCSFSC--SCQNGGTCDSVTGACRCPPGVSGTNC 594
C C GW G C++ P + + S SC C + G C V G C C PG +G +C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRC--VRGRCVCFPGYTGPSC 213
Query: 595 E-DGCP-----------------KGYYGKHCRKKC---NCANRGRCHRLYGACLCDPGLY 633
CP G+ G C ++ C+ RGRC G C+CDPG
Sbjct: 214 GWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG--GRCVCDPGYT 271
Query: 634 GRFCHL-TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFG 692
G C + +CP GCS+ +C +G C C G+ GE +C +
Sbjct: 272 GDDCGMRSCP-----RGCSQRGRC----------ENGRCVCNPGYTGE----DCGVRSCP 312
Query: 693 PGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCH 752
GC Q C G C C G+ GEDCG +C C GG
Sbjct: 313 RGCSQRGRCK--------DGRC--VCDPGYTGEDCGTR--------SCPWDCGEGG---R 351
Query: 753 GVTGQCRCPPGRTGEDCEA-DCPEGRWGLG-CQE-----------------ICPA-CQHA 792
V G+C C PG TGEDC CP G G C++ CP C
Sbjct: 352 CVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQR 411
Query: 793 ARCDPETGACLCLPGFVGS---------------RCQD---VCPAGWYGPSCQTRC---S 831
RC E G C+C PG+ G+ RC++ VC AG+ G C R
Sbjct: 412 GRC--EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGD 469
Query: 832 CANDGHCHPATGHCSCAPGWTGFSC------------------QRACDTGHWGPDCSH-- 871
C G C +G C C PG+TG C + C+ G G DC
Sbjct: 470 CRGRGRCE--SGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRR 527
Query: 872 -PCNCSAGHGSCDAISGLCLCEAGYVGPRCE-QQCPQGHFGPGCEQRCQCQHGAACDHVS 929
P +C GHG C+ G+C+C+AGY G C + CP GC R QC +
Sbjct: 528 CPGDC-RGHGLCE--DGVCVCDAGYSGEDCSTRSCP-----GGCRGRGQC--------LD 571
Query: 930 GACTCPAGWRGTFC-EHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA- 987
G C C G+ G C CP +C+ C +G C+C G C+
Sbjct: 572 GRCVCEDGYSGEDCGVRQCPN-----------DCSQHGVCQ--DGVCICWEGYVSEDCSI 618
Query: 988 ETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC-LQACPAGLYGDNCRHSC 1046
TCP++ +G C+ G+C C PG+ GP+C + CPA
Sbjct: 619 RTCPSNCHGR-----------GRCE--EGRCLCDPGYTGPTCATRMCPAD---------- 655
Query: 1047 LCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLC 1106
C+ G C V G C C G+ G C +E P + C GGC LC G+C+C
Sbjct: 656 -CRGRGRC--VQGVCLCHVGYGGEDCGQEEPP---ASAC--PGGCGPRELC--RAGQCVC 705
Query: 1107 PAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163
G+ G C G C CH G+C C G+ G C + P
Sbjct: 706 VEGFRGPDCAIQTCPG----------DCRGRGECH--DGSCVCKDGYAGEDCGEEVP 750
Score = 206 bits (525), Expect = 1e-52
Identities = 253/906 (27%), Positives = 314/906 (34%), Gaps = 301/906 (33%)
Query: 147 CHCPPGFQGPRCQYDVDECRTH-------NGGCQHRCVNTPGSYLCECKPGFRLHTDSRT 199
C CPPG + P +V R G + +C T G + G TD RT
Sbjct: 85 CGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQC--TGGCCPASAQAGTG-QTDVRT 141
Query: 200 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC-------VRRSPCANRN 252
C H V ++R C C PG+ G C + S + +
Sbjct: 142 L------------CSLHGV-FDLSRCTCSCEPGW----GGPTCSDPTDAEIPPSSPPSAS 184
Query: 253 GSCMHRC----QVVRGLARCECHVGYQLAADG-KACEDVDECAAGLAQCAHGCLNTQGSF 307
GSC C + VRG RC C GY + G +C +C G +C G
Sbjct: 185 GSCPDDCNDQGRCVRG--RCVCFPGYTGPSCGWPSCP--GDC-QGRGRCVQGV------- 232
Query: 308 KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTS--AGPLCTCPRGYELDT 365
CVC AG+ G C + C GCS G C C GY
Sbjct: 233 -CVCRAGF----SGPDC-------------SQRSCPRGCSQRGRCEGGRCVCDPGY---- 270
Query: 366 DQRTCIDVDDCADSPC---CQQ--VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSR 420
DDC C C Q C N C C GY + + CG S R
Sbjct: 271 ------TGDDCGMRSCPRGCSQRGRCENG----RCVCNPGY--TGEDCGVRSCPRGCSQR 318
Query: 421 GGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDE 480
G C+ +C C+ GY GE R P
Sbjct: 319 GRCK--------DGRCVCDPGY-------------------TGEDCGTRSCPW------- 344
Query: 481 LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSL-TCD-DCRNGGTCLLGLD 538
D G G + + VC G DCS TC DCR G C G
Sbjct: 345 --------DCG--------EGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG-- 386
Query: 539 GCDCPEGWTGLICN-ETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTN---- 593
C C G++G C +CP D C G C+ G C C PG +GT+
Sbjct: 387 ECICDTGYSGDDCGVRSCPGD-----------CNQRGRCED--GRCVCWPGYTGTDCGSR 433
Query: 594 -----------CEDG---CPKGYYGKHCR-KKC--NCANRGRCHRLYGACLCDPGLYGRF 636
CE+G C GY G+ C + C +C RGRC G C+C PG GR
Sbjct: 434 ACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCES--GRCMCWPGYTGRD 491
Query: 637 CHL-TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE-----RCQAECELGY 690
C CP G G +CV DG C C GF GE RC +C
Sbjct: 492 CGTRACPGDCRGRG-----RCV----------DGRCVCNPGFTGEDCGSRRCPGDCR--- 533
Query: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG-QECPVGTFGVNCSSSCSCGGA 749
G G C GV C AG+ GEDC + CP G C C
Sbjct: 534 -GHG-----LCEDGVCV----------CDAGYSGEDCSTRSCPGG-----CRGRGQC--- 569
Query: 750 PCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFV 809
+ G+C C G +GEDC G ++ C C + G C+C G+V
Sbjct: 570 ----LDGRCVCEDGYSGEDC-----------GVRQCPNDCSQHGVC--QDGVCICWEGYV 612
Query: 810 GSRCQ-DVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSC-QRACDTGHWGP 867
C CP+ +C G C G C C PG+TG +C R C
Sbjct: 613 SEDCSIRTCPS-----------NCHGRGRCE--EGRCLCDPGYTGPTCATRMC------- 652
Query: 868 DCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGP-GCEQRCQCQHGAACD 926
P +C G G C + G+CLC GY G C Q+ P P GC R C+
Sbjct: 653 ----PADC-RGRGRC--VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCR------ 699
Query: 927 HVSGACTCPAGWRGTFCE-HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPR 985
+G C C G+RG C CP DCR C +GSC+C G G
Sbjct: 700 --AGQCVCVEGFRGPDCAIQTCPG-----DCRGRGECH--------DGSCVCKDGYAGED 744
Query: 986 CAETCP 991
C E P
Sbjct: 745 CGEEVP 750
Score = 181 bits (458), Expect = 6e-45
Identities = 238/867 (27%), Positives = 292/867 (33%), Gaps = 269/867 (31%)
Query: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVD------ 163
CC Q + + CS F RC C C PG+ GP C D
Sbjct: 125 CCPASAQAGTGQTDVRTLCSLHGVFDLSRCT------CSCEPGWGGPTCSDPTDAEIPPS 178
Query: 164 ECRTHNGGCQHRCVNTPGSYL---CECKPGFRLHTDSRTCLAINSCALGNGGCQ--HHCV 218
+ +G C C N G + C C PG+ + SC G CQ CV
Sbjct: 179 SPPSASGSCPDDC-NDQGRCVRGRCVCFPGY-----TGPSCGWPSCP---GDCQGRGRCV 229
Query: 219 QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAA 278
Q C CR GF G C +RS R S RC+ RC C GY
Sbjct: 230 QGV-----CVCRAGF----SGPDCSQRS--CPRGCSQRGRCEG----GRCVCDPGY---- 270
Query: 279 DGKACEDVDECAAGLAQCAHGCLNTQG---SFKCVCHAGYELGADGRQCYRIEMEIVNSC 335
D+C G+ C GC + +G + +CVC+ GY G C V SC
Sbjct: 271 ------TGDDC--GMRSCPRGC-SQRGRCENGRCVCNPGY----TGEDCG------VRSC 311
Query: 336 E---ANNGGCSHGCSHTSAGPLCTCPRGYE-LDTDQRTCIDVDDCADSPCCQQVCTNNPG 391
+ G C G C C GY D R+C DC + C
Sbjct: 312 PRGCSQRGRCKDG--------RCVCDPGYTGEDCGTRSC--PWDCGEGGRCVD------- 354
Query: 392 GYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 451
C C+ GY + + C RG CE +C C+ GY
Sbjct: 355 -GRCVCWPGY--TGEDCSTRTCPRDCRGRGRCE--------DGECICDTGY--------- 394
Query: 452 SPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVC 511
G+ VR P + RG + VC
Sbjct: 395 ----------SGDDCGVRSCP----------------------GDCNQRG-RCEDGRCVC 421
Query: 512 LDDSFGHDC-SLTCD-DCRNGGTCLLGLDGCDCPEGWTGLICN-ETCPPDTFGKNCSFSC 568
G DC S C DCR G C G+ C C G++G C +CP D
Sbjct: 422 WPGYTGTDCGSRACPRDCRGRGRCENGV--CVCNAGYSGEDCGVRSCPGD---------- 469
Query: 569 SCQNGGTCDSVTGACRCPPGVSGTNC-EDGCPKGYYGKHCRKKCNCANRGRCHRLYGACL 627
C+ G C+S G C C PG +G +C CP +C RGRC + G C+
Sbjct: 470 -CRGRGRCES--GRCMCWPGYTGRDCGTRACPG-----------DCRGRGRC--VDGRCV 513
Query: 628 CDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQA-E 685
C+PG G C CP G G E DG C C AG+ GE C
Sbjct: 514 CNPGFTGEDCGSRRCPGDCRGHGLCE---------------DGVCVCDAGYSGEDCSTRS 558
Query: 686 CELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS 745
C G G G + G C C G+ GEDCG C + CS
Sbjct: 559 CPGGCRGRG-------------QCLDGRC--VCEDGYSGEDCGVR--------QCPNDCS 595
Query: 746 CGGAPCHGVTGQCRCPPGRTGEDCE-ADCPEGRWGLGCQEICPACQHAARCDPETGACLC 804
G GV C C G EDC CP G G RC E G CLC
Sbjct: 596 QHGVCQDGV---CICWEGYVSEDCSIRTCPSNCHGRG------------RC--EEGRCLC 638
Query: 805 LPGFVGSRCQD-VCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTG 863
PG+ G C +CPA C G C G C C G+ G C G
Sbjct: 639 DPGYTGPTCATRMCPA-----------DCRGRGRC--VQGVCLCHVGYGGEDC------G 679
Query: 864 HWGPDCSHPCNCSAGHGSCDAI-SGLCLCEAGYVGPRCE-QQCPQGHFGPGCEQRCQCQH 921
P S C G G + +G C+C G+ GP C Q CP C R +C
Sbjct: 680 QEEPPAS---ACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCP-----GDCRGRGECH- 730
Query: 922 GAACDHVSGACTCPAGWRGTFCEHACP 948
G+C C G+ G C P
Sbjct: 731 -------DGSCVCKDGYAGEDCGEEVP 750
Score = 115 bits (289), Expect = 3e-25
Identities = 197/733 (26%), Positives = 237/733 (32%), Gaps = 228/733 (31%)
Query: 27 PVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQPCVQALSHTVPVWKAGCGWQAW---C 83
P A +PP P C +Q + GR CV +T P CGW + C
Sbjct: 170 PTDAEIPPSSPPSASGSCPDDCNDQGRCVRGR---CVCFPGYTGP----SCGWPSCPGDC 222
Query: 84 VGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEG--CL------SAECSASLCFH 135
G R R ++ + C RG Q+ EG C+ +C C
Sbjct: 223 QGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR 282
Query: 136 G----GRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGF 191
G GRC G C C PG+ G C R+ GC R G C C PG+
Sbjct: 283 GCSQRGRCENGR---CVCNPGYTGEDCGV-----RSCPRGCSQRGRCKDGR--CVCDPGY 332
Query: 192 RLHTDSRTCLAINSCA--LGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCA 249
C SC G GG CV RC C PG+ G C R+
Sbjct: 333 T----GEDC-GTRSCPWDCGEGG---RCVD-----GRCVCWPGYT----GEDCSTRT--- 372
Query: 250 NRNGSCMHRCQVVRGLARCE-----CHVGYQLAADGKA-----CEDVDECAAGLAQCAHG 299
C C RG RCE C GY G C C G C G
Sbjct: 373 -----CPRDC---RGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPG 424
Query: 300 CLNTQGSFK----------------CVCHAGYELGADGRQCYRIEMEIVNSCEAN---NG 340
T + CVC+AGY G C V SC + G
Sbjct: 425 YTGTDCGSRACPRDCRGRGRCENGVCVCNAGY----SGEDCG------VRSCPGDCRGRG 474
Query: 341 GCSHGCSHTSAGPLCTCPRGYE-LDTDQRTCIDVDDC-ADSPCCQQVCTNNPG--GYECG 396
C G C C GY D R C DC C C NPG G +CG
Sbjct: 475 RCESG--------RCMCWPGYTGRDCGTRAC--PGDCRGRGRCVDGRCVCNPGFTGEDCG 524
Query: 397 C------YAGYRLSADG-CGCE---DVDECA--SSRGGCEHHCTNLAGSFQCSCEAGYRL 444
G+ L DG C C+ ++C+ S GGC L G +C CE GY
Sbjct: 525 SRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDG--RCVCEDGY-- 580
Query: 445 HEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHT 504
GE VR P+ +H
Sbjct: 581 -----------------SGEDCGVRQCPNDC-------------------------SQHG 598
Query: 505 LTEKFVCL--DDSFGHDCSL-TC-DDCRNGGTCLLGLDGCDCPEGWTGLIC-NETCPPDT 559
+ + VC+ + DCS+ TC +C G C G C C G+TG C CP D
Sbjct: 599 VCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG--RCLCDPGYTGPTCATRMCPAD- 655
Query: 560 FGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNC------EDGCPKGYYGKHCRKKCNC 613
C+ G C V G C C G G +C CP G C
Sbjct: 656 ----------CRGRGRC--VQGVCLCHVGYGGEDCGQEEPPASACPGG-----------C 692
Query: 614 ANRGRCHRLYGACLCDPGLYGRFCHL-TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCS 672
R C G C+C G G C + TCP G G EC DGSC
Sbjct: 693 GPRELCRA--GQCVCVEGFRGPDCAIQTCPGDCRGRG---EC------------HDGSCV 735
Query: 673 CKAGFRGERCQAE 685
CK G+ GE C E
Sbjct: 736 CKDGYAGEDCGEE 748
>gi|33598931 scavenger receptor class F, member 1 isoform 3 precursor
[Homo sapiens]
Length = 569
Score = 281 bits (718), Expect = 4e-75
Identities = 156/434 (35%), Positives = 186/434 (42%), Gaps = 55/434 (12%)
Query: 912 GCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAV 971
G E + QH S C AGWR E P C C C
Sbjct: 19 GSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVC-VK 71
Query: 972 NGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQ 1031
G C C G G C+ CP +G +C ++C C C+P G C C
Sbjct: 72 PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQ---------- 121
Query: 1032 ACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGC 1091
A +G C C C G CDP +G C C GW C + C A C +
Sbjct: 122 ---ADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQA--- 175
Query: 1092 LNGGLCDPHTGRCLCPAGWTGDKCQ-------SPCLR---------GWFGEACAQRCSCP 1135
TG C+C GW G +C SPC + GW+G C Q+C C
Sbjct: 176 ---------TGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECV 226
Query: 1136 PGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC-SCA 1194
G C +G C CPPGF G+ CE CP GS G CA C N C P TG+C SC
Sbjct: 227 RGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCE 285
Query: 1195 AGYHGPSCQQRCPPGRYGPGCEQLCG-CLNGGSCDAATGAC-RCPTGFLGTDCNLTCPQG 1252
G++G CQQ C PG +G CEQ C C +G +C+ TG C RC G+LG C CP G
Sbjct: 286 PGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTG 345
Query: 1253 RFGPNCTHVCG-CGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG 1311
FG +C C C QG+ CD VTG C+C G G C CP G C C C G
Sbjct: 346 TFGEDCGSTCPTCVQGS-CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG- 403
Query: 1312 LCHASNGSCSCGLG 1325
LCH +GSC G G
Sbjct: 404 LCHPVSGSCQPGSG 417
Score = 278 bits (710), Expect = 4e-74
Identities = 151/393 (38%), Positives = 183/393 (46%), Gaps = 58/393 (14%)
Query: 697 QACTCPVGVACDSVSGE--CGK----RCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAP 750
Q CT P+ D+ + C K RC GF G C CP +G +C SC P
Sbjct: 50 QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESC-----P 104
Query: 751 CHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVG 810
CH GQC P C+AD RWG C+ C AC RCDP TG C C PG+
Sbjct: 105 CHP-HGQCE--PATGACQCQAD----RWGARCEFPC-ACGPHGRCDPATGVCHCEPGWWS 156
Query: 811 SRCQD------------------VCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWT 852
S C+ VC GW+G C RC+C + C +G C+C PGW
Sbjct: 157 STCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNC-HGSPCEQDSGRCACRPGW- 214
Query: 853 GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPG 912
WGP+C C C G C A SG C C G+ G RCE CP G G
Sbjct: 215 ------------WGPECQQQCECVRGR--CSAASGECTCPPGFRGARCELPCPAGSHGVQ 260
Query: 913 CEQRC-QCQHGAACDHVSGAC-TCPAGWRGTFCEHACPAGFFGLDCRSAC-NCTAGAACD 969
C C +C+H C +G+C +C GW GT C+ C G FG C C +C G AC+
Sbjct: 261 CAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACE 320
Query: 970 AVNGSCL-CPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPS 1028
G C C G GPRC + CP T+G +C C SCD V G C C+ G+ GPS
Sbjct: 321 PDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPS 380
Query: 1029 CLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHC 1061
C +CPAG +G+NC C C G C PVSG C
Sbjct: 381 CNASCPAGFHGNNCSVPCECPE-GLCHPVSGSC 412
Score = 267 bits (682), Expect = 7e-71
Identities = 145/410 (35%), Positives = 173/410 (42%), Gaps = 55/410 (13%)
Query: 1017 QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKEC 1076
+ C GW Q C + C CQ C G C C G+ G C C
Sbjct: 38 ELQCCAGWRQKD--QECTIPI----CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRC 90
Query: 1077 LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPP 1136
+ CR S C G C+P TG C C A G +C+ PC +C P
Sbjct: 91 PGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC-------------ACGP 137
Query: 1137 GAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAG 1196
C TG C C PG+ S C + C QC C ATG C C G
Sbjct: 138 HGRCDPATGVCHCEPGWWSSTCRRPC-------------QCNTAAARCEQATGACVCKPG 184
Query: 1197 Y-----------HGPSCQQ-----RCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGF 1240
+ HG C+Q C PG +GP C+Q C C+ G C AA+G C CP GF
Sbjct: 185 WWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RCSAASGECTCPPGF 243
Query: 1241 LGTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTGTC-LCPPGRAGVRCERGCPQNRFG 1298
G C L CP G G C H CG C C P TG+C C PG G +C++ C FG
Sbjct: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFG 303
Query: 1299 VGCEHTCS-CRNGGLCHASNGSCS-CGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC 1356
CE C CR+G C G C C GW G CE CP G +G C C +C
Sbjct: 304 ESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSC 363
Query: 1357 EPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
+ TG C C G++G +C CP GFHG C C C G C P+SG C
Sbjct: 364 DTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSC 412
Score = 259 bits (662), Expect = 1e-68
Identities = 138/374 (36%), Positives = 165/374 (44%), Gaps = 50/374 (13%)
Query: 1016 GQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKE 1075
G C C PG+ G C CP +G +CR SC C G C+P +G C C G CE
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1076 CLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCP 1135
C C G CDP TG C C GW C+ PC C
Sbjct: 133 C-------------ACGPHGRCDPATGVCHCEPGWWSSTCRRPC-------------QCN 166
Query: 1136 PGAA-CHHVTGACRCPPGFTG-----------SGCEQ-----ACPPGSFGEDCAQMCQCP 1178
AA C TGAC C PG+ G S CEQ AC PG +G +C Q C+C
Sbjct: 167 TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECV 226
Query: 1179 GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCG-CLNGGSCDAATGACR-C 1236
C A+G C+C G+ G C+ CP G +G C CG C + C TG+C C
Sbjct: 227 --RGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESC 284
Query: 1237 PTGFLGTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTGTCL-CPPGRAGVRCERGCPQ 1294
G+ GT C C G FG +C C C G AC+P TG C C PG G RCE CP
Sbjct: 285 EPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPT 344
Query: 1295 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS 1354
FG C TC G C G C C G+ G C +CP G +G C + C C
Sbjct: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG- 403
Query: 1355 TCEPATGTCRCGPG 1368
C P +G+C+ G G
Sbjct: 404 LCHPVSGSCQPGSG 417
Score = 257 bits (656), Expect = 7e-68
Identities = 132/364 (36%), Positives = 167/364 (45%), Gaps = 46/364 (12%)
Query: 564 CSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLY 623
C +CQ C G CRC PG G +C CP Y+G CR+ C C G+C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115
Query: 624 GACLCDPGLYGRFCHLTC------------------PPWAFGPGCSEECQCVQPHTQSCD 665
GAC C +G C C P W + C CQC C+
Sbjct: 116 GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGW-WSSTCRRPCQC-NTAAARCE 173
Query: 666 KRDGSCSCKAGFRGERC----------------QAECELGYFGPGCWQACTCPVGVACDS 709
+ G+C CK G+ G RC + C G++GP C Q C C G C +
Sbjct: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RCSA 232
Query: 710 VSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS-C-GGAPCHGVTGQCR-CPPGRTG 766
SGEC CP GF+G C CP G+ GV C+ SC C PC TG C C PG G
Sbjct: 233 ASGEC--TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNG 290
Query: 767 EDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC-LCLPGFVGSRCQDVCPAGWYGPS 825
C+ C G +G C++ CP C+H C+P+TG C C PG++G RC+D CP G +G
Sbjct: 291 TQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGED 350
Query: 826 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI 885
C + C G C TG C C+ G+ G SC +C G G +CS PC C G C +
Sbjct: 351 CGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECP--EGLCHPV 408
Query: 886 SGLC 889
SG C
Sbjct: 409 SGSC 412
Score = 255 bits (651), Expect = 3e-67
Identities = 141/385 (36%), Positives = 173/385 (44%), Gaps = 54/385 (14%)
Query: 1106 CPAGWT--GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163
C AGW +C P G +AC + C G CRC PGF G+ C CP
Sbjct: 41 CCAGWRQKDQECTIPICEG--PDACQKDEVCVK-------PGLCRCKPGFFGAHCSSRCP 91
Query: 1164 PGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG----------- 1212
+G DC + C C C PATG C C A G C+ C G +G
Sbjct: 92 GQYWGPDCRESCPCHPHGQ-CEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHC 150
Query: 1213 -PG-----CEQLCGCLNGGS-CDAATGACRCPTGFLGTDCNL----------------TC 1249
PG C + C C + C+ ATGAC C G+ G C+ C
Sbjct: 151 EPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCAC 210
Query: 1250 PQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS-CR 1308
G +GP C C C +G C +G C CPPG G RCE CP GV C H+C C+
Sbjct: 211 RPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK 269
Query: 1309 NGGLCHASNGSC-SCGLGWTGRHCELACPPGRYGAACHLECS-CHNNSTCEPATGTC-RC 1365
+ C GSC SC GW G C+ C PG +G +C +C C + CEP TG C RC
Sbjct: 270 HNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRC 329
Query: 1366 GPGFYGQACEHPCPPGFHGAGCQGLC-WCQHGAPCDPISGRCLCPAGFHGHFCERGCEPG 1424
PG+ G CE PCP G G C C C G+ CD ++G C+C AG+ G C C G
Sbjct: 330 DPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS-CDTVTGDCVCSAGYWGPSCNASCPAG 388
Query: 1425 SFGEGCHQRCDCDGGAPCDPVTGLC 1449
G C C+C G C PV+G C
Sbjct: 389 FHGNNCSVPCECPEGL-CHPVSGSC 412
Score = 251 bits (640), Expect = 5e-66
Identities = 128/340 (37%), Positives = 150/340 (44%), Gaps = 46/340 (13%)
Query: 1189 GTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLT 1248
G C C G+ G C RCP +GP C + C C G C+ ATGAC+C
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQAD--------- 123
Query: 1249 CPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1308
R+G C C CG CDP TG C C PG C R C N CE
Sbjct: 124 ----RWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ----- 174
Query: 1309 NGGLCHASNGSCSCGLGWTGRHCEL----------------ACPPGRYGAACHLECSCHN 1352
+ G+C C GW GR C AC PG +G C +C C
Sbjct: 175 -------ATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVR 227
Query: 1353 NSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCW-CQHGAPCDPISGRC-LCPA 1410
C A+G C C PGF G CE PCP G HG C C C+H PC P +G C C
Sbjct: 228 GR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
Query: 1411 GFHGHFCERGCEPGSFGEGCHQRCD-CDGGAPCDPVTGLCL-CPPGRSGATCNLDCRRGQ 1468
G++G C++ C PG+FGE C Q+C C G C+P TG C C PG G C C G
Sbjct: 287 GWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGT 346
Query: 1469 FGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1508
FG C C CD V+G C C GY GP+C P
Sbjct: 347 FGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 239 bits (610), Expect = 2e-62
Identities = 132/366 (36%), Positives = 167/366 (45%), Gaps = 51/366 (13%)
Query: 525 DDCRNGGTCLL-GLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583
D C+ C+ GL C C G+ G C+ CP +G +C SC C G C+ TGAC
Sbjct: 61 DACQKDEVCVKPGL--CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC 118
Query: 584 RCPPGVSGTNCEDGCPKGYYGK-----------------HCRKKCNC-ANRGRCHRLYGA 625
+C G CE C G +G+ CR+ C C RC + GA
Sbjct: 119 QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGA 178
Query: 626 CLCDPGLYGRFCHLTC-----------------PPWAFGPGCSEECQCVQPHTQSCDKRD 668
C+C PG +GR C C P W +GP C ++C+CV+ C
Sbjct: 179 CVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGW-WGPECQQQCECVRGR---CSAAS 234
Query: 669 GSCSCKAGFRGERCQAECELGYFGPGCWQAC-TCPVGVACDSVSGECGKRCPAGFQGEDC 727
G C+C GFRG RC+ C G G C +C C C +G C + C G+ G C
Sbjct: 235 GECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC-ESCEPGWNGTQC 293
Query: 728 GQECPVGTFGVNCSSSC-SC-GGAPCHGVTGQC-RCPPGRTGEDCEADCPEGRWGLGCQE 784
Q C GTFG +C C C G C TG C RC PG G CE CP G +G C
Sbjct: 294 QQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGS 353
Query: 785 ICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGH 844
CP C + CD TG C+C G+ G C CPAG++G +C C C +G CHP +G
Sbjct: 354 TCPTCVQGS-CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECP-EGLCHPVSG- 410
Query: 845 CSCAPG 850
SC PG
Sbjct: 411 -SCQPG 415
Score = 184 bits (466), Expect = 7e-46
Identities = 101/287 (35%), Positives = 129/287 (44%), Gaps = 37/287 (12%)
Query: 520 CSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSV 579
C C C C C GW +G+ CSF C+C +G C+
Sbjct: 159 CRRPCQCNTAAARCEQATGACVCKPGW-------------WGRRCSFRCNC-HGSPCEQD 204
Query: 580 TGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL 639
+G C C P G++G C+++C C RGRC G C C PG G C L
Sbjct: 205 SGRCACRP-------------GWWGPECQQQCECV-RGRCSAASGECTCPPGFRGARCEL 250
Query: 640 TCPPWAFGPGCSEEC-QCVQPHTQSCDKRDGSC-SCKAGFRGERCQAECELGYFGPGCWQ 697
CP + G C+ C +C H + C GSC SC+ G+ G +CQ C G FG C Q
Sbjct: 251 PCPAGSHGVQCAHSCGRC--KHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ 308
Query: 698 ACT-CPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSC-SCGGAPCHGVT 755
C C G AC+ +G C +RC G+ G C CP GTFG +C S+C +C C VT
Sbjct: 309 QCPHCRHGEACEPDTGHC-QRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVT 367
Query: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC 802
G C C G G C A CP G G C C + C P +G+C
Sbjct: 368 GDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE--GLCHPVSGSC 412
Score = 145 bits (365), Expect = 4e-34
Identities = 136/510 (26%), Positives = 175/510 (34%), Gaps = 121/510 (23%)
Query: 173 QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232
QH CV + S +C G+R T I C G CQ ++ + C+C+PG
Sbjct: 27 QHVCVASSPSAELQCCAGWRQKDQECT---IPICE-GPDACQKD--EVCVKPGLCRCKPG 80
Query: 233 FQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAG 292
F G HC R P C C CH Q CE A G
Sbjct: 81 FF----GAHCSSRCPGQYWGPDCRESCP---------CHPHGQ-------CEP----ATG 116
Query: 293 LAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAG 352
QC + F C C G GR C+ G
Sbjct: 117 ACQCQADRWGARCEFPCAC------GPHGR------------CDPATG------------ 146
Query: 353 PLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE- 411
+C C G+ T +R C A C PG + C +R + G CE
Sbjct: 147 -VCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRC--SFRCNCHGSPCEQ 203
Query: 412 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL 471
D CA G C QC C G CS GE
Sbjct: 204 DSGRCACRPGWWGPECQQ-----QCECVRGR--------CSAAS-------GECTCP--- 240
Query: 472 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG 531
P + ELP C S G C+ +C C++
Sbjct: 241 PGFRGARCELP----------------------------CPAGSHGVQCAHSCGRCKHNE 272
Query: 532 TCLLGLDGCD-CPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGTCDSVTGAC-RCPPG 588
C C+ C GW G C + C P TFG++C C C++G C+ TG C RC PG
Sbjct: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPG 332
Query: 589 VSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP 648
G CED CP G +G+ C C +G C + G C+C G +G C+ +CP G
Sbjct: 333 WLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392
Query: 649 GCSEECQCVQPHTQSCDKRDGSCSCKAGFR 678
CS C+C + C GSC +G R
Sbjct: 393 NCSVPCECPE---GLCHPVSGSCQPGSGSR 419
Score = 80.9 bits (198), Expect = 9e-15
Identities = 100/397 (25%), Positives = 131/397 (32%), Gaps = 110/397 (27%)
Query: 82 WCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSA-------SLCF 134
W G + + G + L+CC GW Q+ E C C +C
Sbjct: 13 WTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQE--CTIPICEGPDACQKDEVCV 70
Query: 135 HGG--RCVP---GSAQPCHCPPGFQGPRCQ-----YDVDECRTHNGGCQ----------- 173
G RC P G+ CP + GP C+ + +C G CQ
Sbjct: 71 KPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCE 130
Query: 174 --------HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 225
RC P + +C C+PG+ T R C + A C Q T
Sbjct: 131 FPCACGPHGRC--DPATGVCHCEPGWWSSTCRRPCQCNTAAA--------RCEQAT---G 177
Query: 226 RCQCRPGFQLQEDGRHCVRR-----SPCANRNG-----------SCMHRCQVVRG----- 264
C C+PG+ GR C R SPC +G C +C+ VRG
Sbjct: 178 ACVCKPGWW----GRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAA 233
Query: 265 LARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAG----YELGAD 320
C C G++ G CE + QCAH C + + C G E G +
Sbjct: 234 SGECTCPPGFR----GARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289
Query: 321 GRQCYR--IEMEIVNSCEANNGGCSHG------------CSHTSAGPLC--TCPRGYELD 364
G QC + + SCE C HG C GP C CP G +
Sbjct: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGE 349
Query: 365 TDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGY 401
TC C Q C G +C C AGY
Sbjct: 350 DCGSTC--------PTCVQGSCDTVTG--DCVCSAGY 376
Score = 70.9 bits (172), Expect = 9e-12
Identities = 71/255 (27%), Positives = 89/255 (34%), Gaps = 51/255 (20%)
Query: 122 GCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPG 181
G CS HG C S + C C PG+ GP CQ +C G C +
Sbjct: 184 GWWGRRCSFRCNCHGSPCEQDSGR-CACRPGWWGPECQ---QQCECVRGRC------SAA 233
Query: 182 SYLCECKPGFRLHTDSRTCLAIN---SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 238
S C C PGFR C A + CA G C+H+ T C PG+ +
Sbjct: 234 SGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW----N 289
Query: 239 GRHCVRRSPC--ANRNGSCMHRCQVVRGLARCECHVGYQLAAD----GKACEDV------ 286
G C + PC SC +C R CE G+ D G CED
Sbjct: 290 GTQC--QQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTF 347
Query: 287 -DECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG 345
++C + C G +T + CVC AGY G C N C G
Sbjct: 348 GEDCGSTCPTCVQGSCDTV-TGDCVCSAGYW----GPSC--------------NASCPAG 388
Query: 346 CSHTSAGPLCTCPRG 360
+ C CP G
Sbjct: 389 FHGNNCSVPCECPEG 403
Score = 53.5 bits (127), Expect = 2e-06
Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1436 CDGGAPC--DPVT---GLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSG 1490
C+G C D V GLC C PG GA C+ C +GP C C C C+P +G
Sbjct: 57 CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATG 116
Query: 1491 QCHCVDGYMGPTC 1503
C C G C
Sbjct: 117 ACQCQADRWGARC 129
Score = 40.4 bits (93), Expect = 0.013
Identities = 37/133 (27%), Positives = 43/133 (32%), Gaps = 31/133 (23%)
Query: 110 CCRGW----MQQPDEEGCLSAECSASL--CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVD 163
C GW QQP G C C HG C P + C PG+ GPRC+ D
Sbjct: 284 CEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE---D 340
Query: 164 ECRTHNGG----------CQHRCVNTPGSYLC-----------ECKPGFRLHTDSRTCLA 202
C T G Q C G +C C GF + S C
Sbjct: 341 PCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC 400
Query: 203 INS-CALGNGGCQ 214
C +G CQ
Sbjct: 401 PEGLCHPVSGSCQ 413
>gi|33598929 scavenger receptor class F, member 1 isoform 1 precursor
[Homo sapiens]
Length = 830
Score = 281 bits (718), Expect = 4e-75
Identities = 156/434 (35%), Positives = 186/434 (42%), Gaps = 55/434 (12%)
Query: 912 GCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAV 971
G E + QH S C AGWR E P C C C
Sbjct: 19 GSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVC-VK 71
Query: 972 NGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQ 1031
G C C G G C+ CP +G +C ++C C C+P G C C
Sbjct: 72 PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQ---------- 121
Query: 1032 ACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGC 1091
A +G C C C G CDP +G C C GW C + C A C +
Sbjct: 122 ---ADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQA--- 175
Query: 1092 LNGGLCDPHTGRCLCPAGWTGDKCQ-------SPCLR---------GWFGEACAQRCSCP 1135
TG C+C GW G +C SPC + GW+G C Q+C C
Sbjct: 176 ---------TGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECV 226
Query: 1136 PGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC-SCA 1194
G C +G C CPPGF G+ CE CP GS G CA C N C P TG+C SC
Sbjct: 227 RGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCE 285
Query: 1195 AGYHGPSCQQRCPPGRYGPGCEQLCG-CLNGGSCDAATGAC-RCPTGFLGTDCNLTCPQG 1252
G++G CQQ C PG +G CEQ C C +G +C+ TG C RC G+LG C CP G
Sbjct: 286 PGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTG 345
Query: 1253 RFGPNCTHVCG-CGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG 1311
FG +C C C QG+ CD VTG C+C G G C CP G C C C G
Sbjct: 346 TFGEDCGSTCPTCVQGS-CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG- 403
Query: 1312 LCHASNGSCSCGLG 1325
LCH +GSC G G
Sbjct: 404 LCHPVSGSCQPGSG 417
Score = 278 bits (710), Expect = 4e-74
Identities = 151/393 (38%), Positives = 183/393 (46%), Gaps = 58/393 (14%)
Query: 697 QACTCPVGVACDSVSGE--CGK----RCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAP 750
Q CT P+ D+ + C K RC GF G C CP +G +C SC P
Sbjct: 50 QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESC-----P 104
Query: 751 CHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVG 810
CH GQC P C+AD RWG C+ C AC RCDP TG C C PG+
Sbjct: 105 CHP-HGQCE--PATGACQCQAD----RWGARCEFPC-ACGPHGRCDPATGVCHCEPGWWS 156
Query: 811 SRCQD------------------VCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWT 852
S C+ VC GW+G C RC+C + C +G C+C PGW
Sbjct: 157 STCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNC-HGSPCEQDSGRCACRPGW- 214
Query: 853 GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPG 912
WGP+C C C G C A SG C C G+ G RCE CP G G
Sbjct: 215 ------------WGPECQQQCECVRGR--CSAASGECTCPPGFRGARCELPCPAGSHGVQ 260
Query: 913 CEQRC-QCQHGAACDHVSGAC-TCPAGWRGTFCEHACPAGFFGLDCRSAC-NCTAGAACD 969
C C +C+H C +G+C +C GW GT C+ C G FG C C +C G AC+
Sbjct: 261 CAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACE 320
Query: 970 AVNGSCL-CPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPS 1028
G C C G GPRC + CP T+G +C C SCD V G C C+ G+ GPS
Sbjct: 321 PDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPS 380
Query: 1029 CLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHC 1061
C +CPAG +G+NC C C G C PVSG C
Sbjct: 381 CNASCPAGFHGNNCSVPCECPE-GLCHPVSGSC 412
Score = 267 bits (682), Expect = 7e-71
Identities = 145/410 (35%), Positives = 173/410 (42%), Gaps = 55/410 (13%)
Query: 1017 QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKEC 1076
+ C GW Q C + C CQ C G C C G+ G C C
Sbjct: 38 ELQCCAGWRQKD--QECTIPI----CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRC 90
Query: 1077 LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPP 1136
+ CR S C G C+P TG C C A G +C+ PC +C P
Sbjct: 91 PGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC-------------ACGP 137
Query: 1137 GAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAG 1196
C TG C C PG+ S C + C QC C ATG C C G
Sbjct: 138 HGRCDPATGVCHCEPGWWSSTCRRPC-------------QCNTAAARCEQATGACVCKPG 184
Query: 1197 Y-----------HGPSCQQ-----RCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGF 1240
+ HG C+Q C PG +GP C+Q C C+ G C AA+G C CP GF
Sbjct: 185 WWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RCSAASGECTCPPGF 243
Query: 1241 LGTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTGTC-LCPPGRAGVRCERGCPQNRFG 1298
G C L CP G G C H CG C C P TG+C C PG G +C++ C FG
Sbjct: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFG 303
Query: 1299 VGCEHTCS-CRNGGLCHASNGSCS-CGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC 1356
CE C CR+G C G C C GW G CE CP G +G C C +C
Sbjct: 304 ESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSC 363
Query: 1357 EPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
+ TG C C G++G +C CP GFHG C C C G C P+SG C
Sbjct: 364 DTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSC 412
Score = 259 bits (662), Expect = 1e-68
Identities = 138/374 (36%), Positives = 165/374 (44%), Gaps = 50/374 (13%)
Query: 1016 GQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKE 1075
G C C PG+ G C CP +G +CR SC C G C+P +G C C G CE
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 1076 CLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCP 1135
C C G CDP TG C C GW C+ PC C
Sbjct: 133 C-------------ACGPHGRCDPATGVCHCEPGWWSSTCRRPC-------------QCN 166
Query: 1136 PGAA-CHHVTGACRCPPGFTG-----------SGCEQ-----ACPPGSFGEDCAQMCQCP 1178
AA C TGAC C PG+ G S CEQ AC PG +G +C Q C+C
Sbjct: 167 TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECV 226
Query: 1179 GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCG-CLNGGSCDAATGACR-C 1236
C A+G C+C G+ G C+ CP G +G C CG C + C TG+C C
Sbjct: 227 --RGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESC 284
Query: 1237 PTGFLGTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTGTCL-CPPGRAGVRCERGCPQ 1294
G+ GT C C G FG +C C C G AC+P TG C C PG G RCE CP
Sbjct: 285 EPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPT 344
Query: 1295 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS 1354
FG C TC G C G C C G+ G C +CP G +G C + C C
Sbjct: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG- 403
Query: 1355 TCEPATGTCRCGPG 1368
C P +G+C+ G G
Sbjct: 404 LCHPVSGSCQPGSG 417
Score = 257 bits (656), Expect = 7e-68
Identities = 132/364 (36%), Positives = 167/364 (45%), Gaps = 46/364 (12%)
Query: 564 CSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLY 623
C +CQ C G CRC PG G +C CP Y+G CR+ C C G+C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115
Query: 624 GACLCDPGLYGRFCHLTC------------------PPWAFGPGCSEECQCVQPHTQSCD 665
GAC C +G C C P W + C CQC C+
Sbjct: 116 GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGW-WSSTCRRPCQC-NTAAARCE 173
Query: 666 KRDGSCSCKAGFRGERC----------------QAECELGYFGPGCWQACTCPVGVACDS 709
+ G+C CK G+ G RC + C G++GP C Q C C G C +
Sbjct: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RCSA 232
Query: 710 VSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS-C-GGAPCHGVTGQCR-CPPGRTG 766
SGEC CP GF+G C CP G+ GV C+ SC C PC TG C C PG G
Sbjct: 233 ASGEC--TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNG 290
Query: 767 EDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC-LCLPGFVGSRCQDVCPAGWYGPS 825
C+ C G +G C++ CP C+H C+P+TG C C PG++G RC+D CP G +G
Sbjct: 291 TQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGED 350
Query: 826 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI 885
C + C G C TG C C+ G+ G SC +C G G +CS PC C G C +
Sbjct: 351 CGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECP--EGLCHPV 408
Query: 886 SGLC 889
SG C
Sbjct: 409 SGSC 412
Score = 255 bits (651), Expect = 3e-67
Identities = 141/385 (36%), Positives = 173/385 (44%), Gaps = 54/385 (14%)
Query: 1106 CPAGWT--GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163
C AGW +C P G +AC + C G CRC PGF G+ C CP
Sbjct: 41 CCAGWRQKDQECTIPICEG--PDACQKDEVCVK-------PGLCRCKPGFFGAHCSSRCP 91
Query: 1164 PGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG----------- 1212
+G DC + C C C PATG C C A G C+ C G +G
Sbjct: 92 GQYWGPDCRESCPCHPHGQ-CEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHC 150
Query: 1213 -PG-----CEQLCGCLNGGS-CDAATGACRCPTGFLGTDCNL----------------TC 1249
PG C + C C + C+ ATGAC C G+ G C+ C
Sbjct: 151 EPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCAC 210
Query: 1250 PQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS-CR 1308
G +GP C C C +G C +G C CPPG G RCE CP GV C H+C C+
Sbjct: 211 RPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK 269
Query: 1309 NGGLCHASNGSC-SCGLGWTGRHCELACPPGRYGAACHLECS-CHNNSTCEPATGTC-RC 1365
+ C GSC SC GW G C+ C PG +G +C +C C + CEP TG C RC
Sbjct: 270 HNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRC 329
Query: 1366 GPGFYGQACEHPCPPGFHGAGCQGLC-WCQHGAPCDPISGRCLCPAGFHGHFCERGCEPG 1424
PG+ G CE PCP G G C C C G+ CD ++G C+C AG+ G C C G
Sbjct: 330 DPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS-CDTVTGDCVCSAGYWGPSCNASCPAG 388
Query: 1425 SFGEGCHQRCDCDGGAPCDPVTGLC 1449
G C C+C G C PV+G C
Sbjct: 389 FHGNNCSVPCECPEGL-CHPVSGSC 412
Score = 251 bits (640), Expect = 5e-66
Identities = 128/340 (37%), Positives = 150/340 (44%), Gaps = 46/340 (13%)
Query: 1189 GTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLT 1248
G C C G+ G C RCP +GP C + C C G C+ ATGAC+C
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQAD--------- 123
Query: 1249 CPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1308
R+G C C CG CDP TG C C PG C R C N CE
Sbjct: 124 ----RWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ----- 174
Query: 1309 NGGLCHASNGSCSCGLGWTGRHCEL----------------ACPPGRYGAACHLECSCHN 1352
+ G+C C GW GR C AC PG +G C +C C
Sbjct: 175 -------ATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVR 227
Query: 1353 NSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCW-CQHGAPCDPISGRC-LCPA 1410
C A+G C C PGF G CE PCP G HG C C C+H PC P +G C C
Sbjct: 228 GR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
Query: 1411 GFHGHFCERGCEPGSFGEGCHQRCD-CDGGAPCDPVTGLCL-CPPGRSGATCNLDCRRGQ 1468
G++G C++ C PG+FGE C Q+C C G C+P TG C C PG G C C G
Sbjct: 287 GWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGT 346
Query: 1469 FGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1508
FG C C CD V+G C C GY GP+C P
Sbjct: 347 FGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 239 bits (610), Expect = 2e-62
Identities = 132/366 (36%), Positives = 167/366 (45%), Gaps = 51/366 (13%)
Query: 525 DDCRNGGTCLL-GLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583
D C+ C+ GL C C G+ G C+ CP +G +C SC C G C+ TGAC
Sbjct: 61 DACQKDEVCVKPGL--CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC 118
Query: 584 RCPPGVSGTNCEDGCPKGYYGK-----------------HCRKKCNC-ANRGRCHRLYGA 625
+C G CE C G +G+ CR+ C C RC + GA
Sbjct: 119 QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGA 178
Query: 626 CLCDPGLYGRFCHLTC-----------------PPWAFGPGCSEECQCVQPHTQSCDKRD 668
C+C PG +GR C C P W +GP C ++C+CV+ C
Sbjct: 179 CVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGW-WGPECQQQCECVRGR---CSAAS 234
Query: 669 GSCSCKAGFRGERCQAECELGYFGPGCWQAC-TCPVGVACDSVSGECGKRCPAGFQGEDC 727
G C+C GFRG RC+ C G G C +C C C +G C + C G+ G C
Sbjct: 235 GECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC-ESCEPGWNGTQC 293
Query: 728 GQECPVGTFGVNCSSSC-SC-GGAPCHGVTGQC-RCPPGRTGEDCEADCPEGRWGLGCQE 784
Q C GTFG +C C C G C TG C RC PG G CE CP G +G C
Sbjct: 294 QQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGS 353
Query: 785 ICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGH 844
CP C + CD TG C+C G+ G C CPAG++G +C C C +G CHP +G
Sbjct: 354 TCPTCVQGS-CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECP-EGLCHPVSG- 410
Query: 845 CSCAPG 850
SC PG
Sbjct: 411 -SCQPG 415
Score = 184 bits (466), Expect = 7e-46
Identities = 101/287 (35%), Positives = 129/287 (44%), Gaps = 37/287 (12%)
Query: 520 CSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSV 579
C C C C C GW +G+ CSF C+C +G C+
Sbjct: 159 CRRPCQCNTAAARCEQATGACVCKPGW-------------WGRRCSFRCNC-HGSPCEQD 204
Query: 580 TGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL 639
+G C C P G++G C+++C C RGRC G C C PG G C L
Sbjct: 205 SGRCACRP-------------GWWGPECQQQCECV-RGRCSAASGECTCPPGFRGARCEL 250
Query: 640 TCPPWAFGPGCSEEC-QCVQPHTQSCDKRDGSC-SCKAGFRGERCQAECELGYFGPGCWQ 697
CP + G C+ C +C H + C GSC SC+ G+ G +CQ C G FG C Q
Sbjct: 251 PCPAGSHGVQCAHSCGRC--KHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ 308
Query: 698 ACT-CPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSC-SCGGAPCHGVT 755
C C G AC+ +G C +RC G+ G C CP GTFG +C S+C +C C VT
Sbjct: 309 QCPHCRHGEACEPDTGHC-QRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVT 367
Query: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC 802
G C C G G C A CP G G C C + C P +G+C
Sbjct: 368 GDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE--GLCHPVSGSC 412
Score = 145 bits (365), Expect = 4e-34
Identities = 136/510 (26%), Positives = 175/510 (34%), Gaps = 121/510 (23%)
Query: 173 QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232
QH CV + S +C G+R T I C G CQ ++ + C+C+PG
Sbjct: 27 QHVCVASSPSAELQCCAGWRQKDQECT---IPICE-GPDACQKD--EVCVKPGLCRCKPG 80
Query: 233 FQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAG 292
F G HC R P C C CH Q CE A G
Sbjct: 81 FF----GAHCSSRCPGQYWGPDCRESCP---------CHPHGQ-------CEP----ATG 116
Query: 293 LAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAG 352
QC + F C C G GR C+ G
Sbjct: 117 ACQCQADRWGARCEFPCAC------GPHGR------------CDPATG------------ 146
Query: 353 PLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE- 411
+C C G+ T +R C A C PG + C +R + G CE
Sbjct: 147 -VCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRC--SFRCNCHGSPCEQ 203
Query: 412 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL 471
D CA G C QC C G CS GE
Sbjct: 204 DSGRCACRPGWWGPECQQ-----QCECVRGR--------CSAAS-------GECTCP--- 240
Query: 472 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG 531
P + ELP C S G C+ +C C++
Sbjct: 241 PGFRGARCELP----------------------------CPAGSHGVQCAHSCGRCKHNE 272
Query: 532 TCLLGLDGCD-CPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGTCDSVTGAC-RCPPG 588
C C+ C GW G C + C P TFG++C C C++G C+ TG C RC PG
Sbjct: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPG 332
Query: 589 VSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP 648
G CED CP G +G+ C C +G C + G C+C G +G C+ +CP G
Sbjct: 333 WLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN 392
Query: 649 GCSEECQCVQPHTQSCDKRDGSCSCKAGFR 678
CS C+C + C GSC +G R
Sbjct: 393 NCSVPCECPE---GLCHPVSGSCQPGSGSR 419
Score = 80.9 bits (198), Expect = 9e-15
Identities = 100/397 (25%), Positives = 131/397 (32%), Gaps = 110/397 (27%)
Query: 82 WCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSA-------SLCF 134
W G + + G + L+CC GW Q+ E C C +C
Sbjct: 13 WTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQE--CTIPICEGPDACQKDEVCV 70
Query: 135 HGG--RCVP---GSAQPCHCPPGFQGPRCQ-----YDVDECRTHNGGCQ----------- 173
G RC P G+ CP + GP C+ + +C G CQ
Sbjct: 71 KPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCE 130
Query: 174 --------HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 225
RC P + +C C+PG+ T R C + A C Q T
Sbjct: 131 FPCACGPHGRC--DPATGVCHCEPGWWSSTCRRPCQCNTAAA--------RCEQAT---G 177
Query: 226 RCQCRPGFQLQEDGRHCVRR-----SPCANRNG-----------SCMHRCQVVRG----- 264
C C+PG+ GR C R SPC +G C +C+ VRG
Sbjct: 178 ACVCKPGWW----GRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAA 233
Query: 265 LARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAG----YELGAD 320
C C G++ G CE + QCAH C + + C G E G +
Sbjct: 234 SGECTCPPGFR----GARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289
Query: 321 GRQCYR--IEMEIVNSCEANNGGCSHG------------CSHTSAGPLC--TCPRGYELD 364
G QC + + SCE C HG C GP C CP G +
Sbjct: 290 GTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGE 349
Query: 365 TDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGY 401
TC C Q C G +C C AGY
Sbjct: 350 DCGSTC--------PTCVQGSCDTVTG--DCVCSAGY 376
Score = 70.9 bits (172), Expect = 9e-12
Identities = 71/255 (27%), Positives = 89/255 (34%), Gaps = 51/255 (20%)
Query: 122 GCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPG 181
G CS HG C S + C C PG+ GP CQ +C G C +
Sbjct: 184 GWWGRRCSFRCNCHGSPCEQDSGR-CACRPGWWGPECQ---QQCECVRGRC------SAA 233
Query: 182 SYLCECKPGFRLHTDSRTCLAIN---SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED 238
S C C PGFR C A + CA G C+H+ T C PG+ +
Sbjct: 234 SGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW----N 289
Query: 239 GRHCVRRSPC--ANRNGSCMHRCQVVRGLARCECHVGYQLAAD----GKACEDV------ 286
G C + PC SC +C R CE G+ D G CED
Sbjct: 290 GTQC--QQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTF 347
Query: 287 -DECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG 345
++C + C G +T + CVC AGY G C N C G
Sbjct: 348 GEDCGSTCPTCVQGSCDTV-TGDCVCSAGYW----GPSC--------------NASCPAG 388
Query: 346 CSHTSAGPLCTCPRG 360
+ C CP G
Sbjct: 389 FHGNNCSVPCECPEG 403
Score = 53.5 bits (127), Expect = 2e-06
Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1436 CDGGAPC--DPVT---GLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSG 1490
C+G C D V GLC C PG GA C+ C +GP C C C C+P +G
Sbjct: 57 CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATG 116
Query: 1491 QCHCVDGYMGPTC 1503
C C G C
Sbjct: 117 ACQCQADRWGARC 129
Score = 40.4 bits (93), Expect = 0.013
Identities = 37/133 (27%), Positives = 43/133 (32%), Gaps = 31/133 (23%)
Query: 110 CCRGW----MQQPDEEGCLSAECSASL--CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVD 163
C GW QQP G C C HG C P + C PG+ GPRC+ D
Sbjct: 284 CEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE---D 340
Query: 164 ECRTHNGG----------CQHRCVNTPGSYLC-----------ECKPGFRLHTDSRTCLA 202
C T G Q C G +C C GF + S C
Sbjct: 341 PCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC 400
Query: 203 INS-CALGNGGCQ 214
C +G CQ
Sbjct: 401 PEGLCHPVSGSCQ 413
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 264 bits (675), Expect = 4e-70
Identities = 139/397 (35%), Positives = 176/397 (44%), Gaps = 60/397 (15%)
Query: 561 GKNCSFSCSCQNGGTCDSVT-----GACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN 615
G C + C+ TC G CRC G G NC+ CP+ ++G C++ C+C
Sbjct: 72 GDECGIAV-CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP 130
Query: 616 RGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKA 675
G+C + G C TC +G C CQC +C R G+C C+
Sbjct: 131 HGQCEDVTGQC-------------TCHARRWGARCEHACQC---QHGTCHPRSGACRCEP 174
Query: 676 GFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVG- 734
G+ G +C + AC C CD +G C C AG+ G C +C
Sbjct: 175 GWWGAQCAS-------------ACYCSATSRCDPQTGAC--LCHAGWWGRSCNNQCACNS 219
Query: 735 ---------------TFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
TFG C C C CH V G C C PG G+ C CP G +G
Sbjct: 220 SPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYG 279
Query: 780 LGCQEICPACQHAARCDPETGACL-CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGH- 837
LGC+ C C+ C G CL C PG+ G++C C G+YG C RC DGH
Sbjct: 280 LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHA 339
Query: 838 CHPATGHCS-CAPGWTGFSCQRACDTGHWGPDCSHPC-NCSAGHGSCDAISGLCLCEAGY 895
C+ TG C+ C GW G C+ C G +G DC+ C +C +GH CD SG CLC G
Sbjct: 340 CNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH--CDFQSGRCLCSPGV 397
Query: 896 VGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGAC 932
GP C CP G G C Q C C H CD V+GAC
Sbjct: 398 HGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGAC 433
Score = 262 bits (669), Expect = 2e-69
Identities = 143/384 (37%), Positives = 175/384 (45%), Gaps = 48/384 (12%)
Query: 672 SCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQEC 731
+C AG+R + EC + C TC C GEC RC G+ G +C +C
Sbjct: 63 TCCAGWRQQG--DECGIAV----CEGNSTCSENEVCVR-PGEC--RCRHGYFGANCDTKC 113
Query: 732 PVGTFGVNCSSSCSCGG-APCHGVTGQCRCPPGRTGEDCE----------------ADCP 774
P +G +C CSC C VTGQC C R G CE C
Sbjct: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCE 173
Query: 775 EGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAG-------------- 820
G WG C C C +RCDP+TGACLC G+ G C + C
Sbjct: 174 PGWWGAQCASAC-YCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCR 232
Query: 821 --WYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAG 878
+G C C C G CHP G C+C PG+ G C+ C G +G C C G
Sbjct: 233 ERTFGARCDRYCQCFR-GRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKG 291
Query: 879 HGSCDAISGLCL-CEAGYVGPRCEQQCPQGHFGPGCEQRCQ-CQHGAACDHVSGACT-CP 935
C G CL CE G+ G +C+Q C G +G GC RC C+ G AC+HV+G CT C
Sbjct: 292 QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCN 351
Query: 936 AGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTY 995
AGW G CE C G +G DC C CD +G CLC G GP C TCP +
Sbjct: 352 AGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH 411
Query: 996 GHNCSQACACFNGASCDPVHGQCH 1019
G +C+QAC+C +CDPV G CH
Sbjct: 412 GADCAQACSCHED-TCDPVTGACH 434
Score = 261 bits (667), Expect = 4e-69
Identities = 137/384 (35%), Positives = 169/384 (44%), Gaps = 51/384 (13%)
Query: 846 SCAPGWT--GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQ 903
+C GW G C A G N + G C C GY G C+ +
Sbjct: 63 TCCAGWRQQGDECGIAVCEG----------NSTCSENEVCVRPGECRCRHGYFGANCDTK 112
Query: 904 CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA-------------- 949
CP+ +GP C++ C C C+ V+G CTC A G CEHAC
Sbjct: 113 CPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRC 172
Query: 950 --GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAH-------------- 993
G++G C SAC C+A + CD G+CLC AG G C C +
Sbjct: 173 EPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCR 232
Query: 994 --TYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSC-LCQN 1050
T+G C + C CF G C PV G C C PG+ G C + CPAG YG CR C C+
Sbjct: 233 ERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKG 291
Query: 1051 GGTCDPVSGHC-ACPEGWAGLACEKECLPRDVRAGCRHS-GGCLNGGLCDPHTGRCL-CP 1107
C G C C GW G C++ C GC H C +G C+ TG+C C
Sbjct: 292 QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCN 351
Query: 1108 AGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSF 1167
AGW GD+C++ C G +GE CA C+ C +G C C PG G C CPPG
Sbjct: 352 AGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH 411
Query: 1168 GEDCAQMCQCPGENPACHPATGTC 1191
G DCAQ C C C P TG C
Sbjct: 412 GADCAQACSC--HEDTCDPVTGAC 433
Score = 257 bits (657), Expect = 5e-68
Identities = 135/362 (37%), Positives = 160/362 (44%), Gaps = 40/362 (11%)
Query: 913 CEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVN 972
CE C C G C C G+ G C+ CP F+G DC+ C+C C+ V
Sbjct: 80 CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVT 138
Query: 973 GSCLCPAGRRGPRCAETCPAHT----------------YGHNCSQACACFNGASCDPVHG 1016
G C C A R G RC C +G C+ AC C + CDP G
Sbjct: 139 GQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTG 198
Query: 1017 QCHCAPGWMGPSCLQACPAG----------------LYGDNCRHSCLCQNGGTCDPVSGH 1060
C C GW G SC C +G C C C G C PV G
Sbjct: 199 ACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG-RCHPVDGT 257
Query: 1061 CACPEGWAGLACEKECLPRDVRAGCRHS-GGCLNGGLCDPHTGRCL-CPAGWTGDKCQSP 1118
CAC G+ G C + C GCR G C C GRCL C GW G KC P
Sbjct: 258 CACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP 317
Query: 1119 CLRGWFGEACAQRCS-CPPGAACHHVTGAC-RCPPGFTGSGCEQACPPGSFGEDCAQMCQ 1176
C G++GE C+ RC C G AC+HVTG C RC G+ G CE C G++GEDCA +C
Sbjct: 318 CATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCA 377
Query: 1177 CPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRC 1236
G C +G C C+ G HGP C CPPG +G C Q C C + +CD TGAC
Sbjct: 378 DCGSGH-CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGACHL 435
Query: 1237 PT 1238
T
Sbjct: 436 ET 437
Score = 244 bits (624), Expect = 4e-64
Identities = 130/367 (35%), Positives = 162/367 (44%), Gaps = 45/367 (12%)
Query: 1168 GEDCAQMCQCPG-----ENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCL 1222
G++C + C G EN C G C C GY G +C +CP +GP C++LC C
Sbjct: 72 GDECG-IAVCEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCH 129
Query: 1223 NGGSCDAATGACRCPTGFLGTDCN----------------LTCPQGRFGPNCTHVCGCGQ 1266
G C+ TG C C G C C G +G C C C
Sbjct: 130 PHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSA 189
Query: 1267 GAACDPVTGTCLCPPGRAGVRCERGCPQNR----------------FGVGCEHTCSCRNG 1310
+ CDP TG CLC G G C C N FG C+ C C G
Sbjct: 190 TSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG 249
Query: 1311 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECS-CHNNSTCEPATGTC-RCGPG 1368
CH +G+C+C G+ G++C CP G YG C C C C A G C C PG
Sbjct: 250 R-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPG 308
Query: 1369 FYGQACEHPCPPGFHGAGCQGLCW-CQHGAPCDPISGRCL-CPAGFHGHFCERGCEPGSF 1426
+ G C+ PC GF+G GC C C+ G C+ ++G+C C AG+ G CE C G++
Sbjct: 309 WNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTY 368
Query: 1427 GEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCD 1486
GE C C G CD +G CLC PG G CN+ C G G C C C CD
Sbjct: 369 GEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDT-CD 427
Query: 1487 PVSGQCH 1493
PV+G CH
Sbjct: 428 PVTGACH 434
Score = 243 bits (619), Expect = 1e-63
Identities = 127/360 (35%), Positives = 158/360 (43%), Gaps = 40/360 (11%)
Query: 1083 AGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHH 1142
A C + C +C G C C G+ G C + C R ++G C + CSC P C
Sbjct: 78 AVCEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCED 136
Query: 1143 VTGACRCPPGFTGSGCEQACP----------------PGSFGEDCAQMCQCPGENPACHP 1186
VTG C C G+ CE AC PG +G CA C C + C P
Sbjct: 137 VTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATS-RCDP 195
Query: 1187 ATGTCSCAAGYHGPSCQQRCP---------PGR-------YGPGCEQLCGCLNGGSCDAA 1230
TG C C AG+ G SC +C GR +G C++ C C G C
Sbjct: 196 QTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG-RCHPV 254
Query: 1231 TGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTGTCL-CPPGRAGVRC 1288
G C C G+ G C CP G +G C CG C C G CL C PG G +C
Sbjct: 255 DGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKC 314
Query: 1289 ERGCPQNRFGVGCEHTCS-CRNGGLCHASNGSCS-CGLGWTGRHCELACPPGRYGAACHL 1346
++ C +G GC H C CR+G C+ G C+ C GW G CE C G YG C
Sbjct: 315 DQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAF 374
Query: 1347 ECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
C+ + C+ +G C C PG +G C CPPG HGA C C C H CDP++G C
Sbjct: 375 VCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGAC 433
Score = 242 bits (618), Expect = 2e-63
Identities = 135/382 (35%), Positives = 158/382 (41%), Gaps = 50/382 (13%)
Query: 1106 CPAGWT--GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163
C AGW GD+C C +C C G CRC G+ G+ C+ CP
Sbjct: 64 CCAGWRQQGDECGIA--------VCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCP 114
Query: 1164 PGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ----------------RCP 1207
+G DC ++C C C TG C+C A G C+ RC
Sbjct: 115 RQFWGPDCKELCSCHPHGQ-CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCE 173
Query: 1208 PGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCP---------QGR----- 1253
PG +G C C C CD TGAC C G+ G CN C GR
Sbjct: 174 PGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRE 233
Query: 1254 --FGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS-CRNG 1310
FG C C C +G C PV GTC C PG G C CP +G+GC C C+
Sbjct: 234 RTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQ 292
Query: 1311 GLCHASNGSC-SCGLGWTGRHCELACPPGRYGAACHLECS-CHNNSTCEPATGTC-RCGP 1367
C + G C +C GW G C+ C G YG C C C + C TG C RC
Sbjct: 293 QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNA 352
Query: 1368 GFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFG 1427
G+ G CE C G +G C +C CD SGRCLC G HG C C PG G
Sbjct: 353 GWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHG 412
Query: 1428 EGCHQRCDCDGGAPCDPVTGLC 1449
C Q C C CDPVTG C
Sbjct: 413 ADCAQACSCHEDT-CDPVTGAC 433
Score = 225 bits (574), Expect = 2e-58
Identities = 124/370 (33%), Positives = 158/370 (42%), Gaps = 49/370 (13%)
Query: 517 GHDCSLTCDDCRNGGTC-----LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQ 571
G +C + C TC + C C G+ G C+ CP +G +C CSC
Sbjct: 72 GDECGIAV--CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCH 129
Query: 572 NGGTCDSVTGACRCPPGVSGTNCEDG----------------CPKGYYGKHCRKKCNCAN 615
G C+ VTG C C G CE C G++G C C C+
Sbjct: 130 PHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSA 189
Query: 616 RGRCHRLYGACLCDPGLYGRFCH----------------LTCPPWAFGPGCSEECQCVQP 659
RC GACLC G +GR C+ C FG C CQC +
Sbjct: 190 TSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG 249
Query: 660 HTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQAC-TCPVGVACDSVSGECGKRC 718
C DG+C+C+ G+RG+ C+ C G++G GC + C C C G C C
Sbjct: 250 R---CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRC-LTC 305
Query: 719 PAGFQGEDCGQECPVGTFGVNCSSSC-SC-GGAPCHGVTGQC-RCPPGRTGEDCEADCPE 775
G+ G C Q C G +G CS C C G C+ VTG+C RC G G+ CE C
Sbjct: 306 EPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSN 365
Query: 776 GRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAND 835
G +G C +C C + CD ++G CLC PG G C CP G +G C CSC D
Sbjct: 366 GTYGEDCAFVCADC-GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHED 424
Query: 836 GHCHPATGHC 845
C P TG C
Sbjct: 425 -TCDPVTGAC 433
Score = 224 bits (572), Expect = 4e-58
Identities = 127/364 (34%), Positives = 154/364 (42%), Gaps = 50/364 (13%)
Query: 1179 GENPACHPATGTCSCAAGYH--GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRC 1236
G N P + +C AG+ G C CE C C G CRC
Sbjct: 50 GRNVCRAPGSQVPTCCAGWRQQGDECGIAV--------CEGNSTCSENEVC-VRPGECRC 100
Query: 1237 PTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNR 1296
G+ G +C+ CP+ +GP+C +C C C+ VTG C C R G RCE C
Sbjct: 101 RHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQH 160
Query: 1297 ----------------FGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACP---- 1336
+G C C C C G+C C GW GR C C
Sbjct: 161 GTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSS 220
Query: 1337 -----PGR-------YGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHG 1384
GR +GA C C C C P GTC C PG+ G+ C PCP GF+G
Sbjct: 221 PCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYG 279
Query: 1385 AGCQGLCW-CQHGAPCDPISGRCL-CPAGFHGHFCERGCEPGSFGEGCHQRCD-CDGGAP 1441
GC+ C C+ PC GRCL C G++G C++ C G +GEGC RC C G
Sbjct: 280 LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHA 339
Query: 1442 CDPVTGLCL-CPPGRSGATCNLDCRRGQFGPSCTLHC-DCGGGADCDPVSGQCHCVDGYM 1499
C+ VTG C C G G C C G +G C C DCG G CD SG+C C G
Sbjct: 340 CNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSG-HCDFQSGRCLCSPGVH 398
Query: 1500 GPTC 1503
GP C
Sbjct: 399 GPHC 402
Score = 142 bits (357), Expect = 3e-33
Identities = 127/505 (25%), Positives = 180/505 (35%), Gaps = 127/505 (25%)
Query: 180 PGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDG 239
PGS + C G+R D I C GN C + ++ + C+CR G+ G
Sbjct: 57 PGSQVPTCCAGWRQQGDE---CGIAVCE-GNSTCSEN--EVCVRPGECRCRHGYF----G 106
Query: 240 RHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG 299
+C + P C C CH Q CEDV
Sbjct: 107 ANCDTKCPRQFWGPDCKELCS---------CHPHGQ-------CEDV------------- 137
Query: 300 CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPR 359
+ +C CHA G +C ++C+ C HG H +G C C
Sbjct: 138 ------TGQCTCHARRW----GARCE-------HACQ-----CQHGTCHPRSGA-CRCEP 174
Query: 360 GYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 419
G+ CA + C +P C C+AG+ G C + +CA +
Sbjct: 175 GWW----------GAQCASACYCSATSRCDPQTGACLCHAGWW----GRSCNN--QCACN 218
Query: 420 RGGCEHH---CTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAV 476
CE C +F C+ + R C P++
Sbjct: 219 SSPCEQQSGRCQCRERTFGARCDRYCQCFRGR--CHPVD--------------------- 255
Query: 477 LQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLG 536
G E RG++ + C +G C C C+ C +
Sbjct: 256 --------------GTCACEPGYRGKYC---REPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
Query: 537 LDGC-DCPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGTCDSVTGAC-RCPPGVSGTN 593
C C GW G C++ C +G+ CS C C++G C+ VTG C RC G G
Sbjct: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
Query: 594 CEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEE 653
CE C G YG+ C C G C G CLC PG++G C++TCPP G C++
Sbjct: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418
Query: 654 CQCVQPHTQSCDKRDGSCSCKAGFR 678
C C H +CD G+C + R
Sbjct: 419 CSC---HEDTCDPVTGACHLETNQR 440
Score = 130 bits (328), Expect = 8e-30
Identities = 77/236 (32%), Positives = 93/236 (39%), Gaps = 45/236 (19%)
Query: 1308 RNGGLCHASNGSC-SCGLGWT--GRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCR 1364
R +C A +C GW G C +A C +C N C G CR
Sbjct: 49 RGRNVCRAPGSQVPTCCAGWRQQGDECGIA--------VCEGNSTCSENEVCV-RPGECR 99
Query: 1365 CGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGC--- 1421
C G++G C+ CP F G C+ LC C C+ ++G+C C A G CE C
Sbjct: 100 CRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQ 159
Query: 1422 -------------EPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCN------- 1461
EPG +G C C C + CDP TG CLC G G +CN
Sbjct: 160 HGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNS 219
Query: 1462 ---------LDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1508
CR FG C +C C G C PV G C C GY G CRE P
Sbjct: 220 SPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCP 274
Score = 75.1 bits (183), Expect = 5e-13
Identities = 107/413 (25%), Positives = 131/413 (31%), Gaps = 89/413 (21%)
Query: 97 RQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCV-PGSAQPCH------- 148
R V V CC GW QQ DE G E S C CV PG + H
Sbjct: 51 RNVCRAPGSQVPTCCAGWRQQGDECGIAVCE-GNSTCSENEVCVRPGECRCRHGYFGANC 109
Query: 149 ---CPPGFQGPRCQYDVDECRTH-----------------NGGCQHRC-----VNTPGSY 183
CP F GP C+ ++ C H C+H C P S
Sbjct: 110 DTKCPRQFWGPDCK-ELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSG 168
Query: 184 LCECKPGF--RLHTDSRTCLAINSCALGNGGCQHHCVQL-TITRHRCQCRPGFQLQEDGR 240
C C+PG+ + C A + C G C H ++C C Q+ GR
Sbjct: 169 ACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGR 228
Query: 241 HCVRRSPCANRNGSCMHRCQVVRGLAR-----CECHVGYQLAADGKACEDVDECAAGL-- 293
R R C CQ RG C C GY+ GK C + C AG
Sbjct: 229 CQCRERTFGAR---CDRYCQCFRGRCHPVDGTCACEPGYR----GKYCR--EPCPAGFYG 279
Query: 294 AQCAHGCLNTQGSFKCVCHAG----YELGADGRQCYRIEMEIVNSCEAN--NGGCSHGCS 347
C C +G C G E G +G +C + C GCSH C
Sbjct: 280 LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQ-------PCATGFYGEGCSHRCP 332
Query: 348 HTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADG 407
G C G C + C+ C+N G +C + AD
Sbjct: 333 PCRDGHACNHVTG--------KCTRCNAGWIGDRCETKCSNGTYGEDCAF-----VCAD- 378
Query: 408 CGCEDVD----ECASSRGGCEHHC--TNLAGSFQCSCEAGYRLHEDRRGCSPL 454
CG D C S G HC T G C HED C P+
Sbjct: 379 CGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDT--CDPV 429
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 264 bits (675), Expect = 4e-70
Identities = 139/397 (35%), Positives = 176/397 (44%), Gaps = 60/397 (15%)
Query: 561 GKNCSFSCSCQNGGTCDSVT-----GACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN 615
G C + C+ TC G CRC G G NC+ CP+ ++G C++ C+C
Sbjct: 72 GDECGIAV-CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP 130
Query: 616 RGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKA 675
G+C + G C TC +G C CQC +C R G+C C+
Sbjct: 131 HGQCEDVTGQC-------------TCHARRWGARCEHACQC---QHGTCHPRSGACRCEP 174
Query: 676 GFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVG- 734
G+ G +C + AC C CD +G C C AG+ G C +C
Sbjct: 175 GWWGAQCAS-------------ACYCSATSRCDPQTGAC--LCHAGWWGRSCNNQCACNS 219
Query: 735 ---------------TFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
TFG C C C CH V G C C PG G+ C CP G +G
Sbjct: 220 SPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYG 279
Query: 780 LGCQEICPACQHAARCDPETGACL-CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGH- 837
LGC+ C C+ C G CL C PG+ G++C C G+YG C RC DGH
Sbjct: 280 LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHA 339
Query: 838 CHPATGHCS-CAPGWTGFSCQRACDTGHWGPDCSHPC-NCSAGHGSCDAISGLCLCEAGY 895
C+ TG C+ C GW G C+ C G +G DC+ C +C +GH CD SG CLC G
Sbjct: 340 CNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH--CDFQSGRCLCSPGV 397
Query: 896 VGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGAC 932
GP C CP G G C Q C C H CD V+GAC
Sbjct: 398 HGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGAC 433
Score = 262 bits (669), Expect = 2e-69
Identities = 143/384 (37%), Positives = 175/384 (45%), Gaps = 48/384 (12%)
Query: 672 SCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQEC 731
+C AG+R + EC + C TC C GEC RC G+ G +C +C
Sbjct: 63 TCCAGWRQQG--DECGIAV----CEGNSTCSENEVCVR-PGEC--RCRHGYFGANCDTKC 113
Query: 732 PVGTFGVNCSSSCSCGG-APCHGVTGQCRCPPGRTGEDCE----------------ADCP 774
P +G +C CSC C VTGQC C R G CE C
Sbjct: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCE 173
Query: 775 EGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAG-------------- 820
G WG C C C +RCDP+TGACLC G+ G C + C
Sbjct: 174 PGWWGAQCASAC-YCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCR 232
Query: 821 --WYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAG 878
+G C C C G CHP G C+C PG+ G C+ C G +G C C G
Sbjct: 233 ERTFGARCDRYCQCFR-GRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKG 291
Query: 879 HGSCDAISGLCL-CEAGYVGPRCEQQCPQGHFGPGCEQRCQ-CQHGAACDHVSGACT-CP 935
C G CL CE G+ G +C+Q C G +G GC RC C+ G AC+HV+G CT C
Sbjct: 292 QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCN 351
Query: 936 AGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTY 995
AGW G CE C G +G DC C CD +G CLC G GP C TCP +
Sbjct: 352 AGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH 411
Query: 996 GHNCSQACACFNGASCDPVHGQCH 1019
G +C+QAC+C +CDPV G CH
Sbjct: 412 GADCAQACSCHED-TCDPVTGACH 434
Score = 261 bits (667), Expect = 4e-69
Identities = 137/384 (35%), Positives = 169/384 (44%), Gaps = 51/384 (13%)
Query: 846 SCAPGWT--GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQ 903
+C GW G C A G N + G C C GY G C+ +
Sbjct: 63 TCCAGWRQQGDECGIAVCEG----------NSTCSENEVCVRPGECRCRHGYFGANCDTK 112
Query: 904 CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA-------------- 949
CP+ +GP C++ C C C+ V+G CTC A G CEHAC
Sbjct: 113 CPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRC 172
Query: 950 --GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAH-------------- 993
G++G C SAC C+A + CD G+CLC AG G C C +
Sbjct: 173 EPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCR 232
Query: 994 --TYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSC-LCQN 1050
T+G C + C CF G C PV G C C PG+ G C + CPAG YG CR C C+
Sbjct: 233 ERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKG 291
Query: 1051 GGTCDPVSGHC-ACPEGWAGLACEKECLPRDVRAGCRHS-GGCLNGGLCDPHTGRCL-CP 1107
C G C C GW G C++ C GC H C +G C+ TG+C C
Sbjct: 292 QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCN 351
Query: 1108 AGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSF 1167
AGW GD+C++ C G +GE CA C+ C +G C C PG G C CPPG
Sbjct: 352 AGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH 411
Query: 1168 GEDCAQMCQCPGENPACHPATGTC 1191
G DCAQ C C C P TG C
Sbjct: 412 GADCAQACSC--HEDTCDPVTGAC 433
Score = 257 bits (657), Expect = 5e-68
Identities = 135/362 (37%), Positives = 160/362 (44%), Gaps = 40/362 (11%)
Query: 913 CEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVN 972
CE C C G C C G+ G C+ CP F+G DC+ C+C C+ V
Sbjct: 80 CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVT 138
Query: 973 GSCLCPAGRRGPRCAETCPAHT----------------YGHNCSQACACFNGASCDPVHG 1016
G C C A R G RC C +G C+ AC C + CDP G
Sbjct: 139 GQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTG 198
Query: 1017 QCHCAPGWMGPSCLQACPAG----------------LYGDNCRHSCLCQNGGTCDPVSGH 1060
C C GW G SC C +G C C C G C PV G
Sbjct: 199 ACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG-RCHPVDGT 257
Query: 1061 CACPEGWAGLACEKECLPRDVRAGCRHS-GGCLNGGLCDPHTGRCL-CPAGWTGDKCQSP 1118
CAC G+ G C + C GCR G C C GRCL C GW G KC P
Sbjct: 258 CACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP 317
Query: 1119 CLRGWFGEACAQRCS-CPPGAACHHVTGAC-RCPPGFTGSGCEQACPPGSFGEDCAQMCQ 1176
C G++GE C+ RC C G AC+HVTG C RC G+ G CE C G++GEDCA +C
Sbjct: 318 CATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCA 377
Query: 1177 CPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRC 1236
G C +G C C+ G HGP C CPPG +G C Q C C + +CD TGAC
Sbjct: 378 DCGSGH-CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGACHL 435
Query: 1237 PT 1238
T
Sbjct: 436 ET 437
Score = 244 bits (624), Expect = 4e-64
Identities = 130/367 (35%), Positives = 162/367 (44%), Gaps = 45/367 (12%)
Query: 1168 GEDCAQMCQCPG-----ENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCL 1222
G++C + C G EN C G C C GY G +C +CP +GP C++LC C
Sbjct: 72 GDECG-IAVCEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCH 129
Query: 1223 NGGSCDAATGACRCPTGFLGTDCN----------------LTCPQGRFGPNCTHVCGCGQ 1266
G C+ TG C C G C C G +G C C C
Sbjct: 130 PHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSA 189
Query: 1267 GAACDPVTGTCLCPPGRAGVRCERGCPQNR----------------FGVGCEHTCSCRNG 1310
+ CDP TG CLC G G C C N FG C+ C C G
Sbjct: 190 TSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG 249
Query: 1311 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECS-CHNNSTCEPATGTC-RCGPG 1368
CH +G+C+C G+ G++C CP G YG C C C C A G C C PG
Sbjct: 250 R-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPG 308
Query: 1369 FYGQACEHPCPPGFHGAGCQGLCW-CQHGAPCDPISGRCL-CPAGFHGHFCERGCEPGSF 1426
+ G C+ PC GF+G GC C C+ G C+ ++G+C C AG+ G CE C G++
Sbjct: 309 WNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTY 368
Query: 1427 GEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCD 1486
GE C C G CD +G CLC PG G CN+ C G G C C C CD
Sbjct: 369 GEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDT-CD 427
Query: 1487 PVSGQCH 1493
PV+G CH
Sbjct: 428 PVTGACH 434
Score = 243 bits (619), Expect = 1e-63
Identities = 127/360 (35%), Positives = 158/360 (43%), Gaps = 40/360 (11%)
Query: 1083 AGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHH 1142
A C + C +C G C C G+ G C + C R ++G C + CSC P C
Sbjct: 78 AVCEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCED 136
Query: 1143 VTGACRCPPGFTGSGCEQACP----------------PGSFGEDCAQMCQCPGENPACHP 1186
VTG C C G+ CE AC PG +G CA C C + C P
Sbjct: 137 VTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATS-RCDP 195
Query: 1187 ATGTCSCAAGYHGPSCQQRCP---------PGR-------YGPGCEQLCGCLNGGSCDAA 1230
TG C C AG+ G SC +C GR +G C++ C C G C
Sbjct: 196 QTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG-RCHPV 254
Query: 1231 TGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTGTCL-CPPGRAGVRC 1288
G C C G+ G C CP G +G C CG C C G CL C PG G +C
Sbjct: 255 DGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKC 314
Query: 1289 ERGCPQNRFGVGCEHTCS-CRNGGLCHASNGSCS-CGLGWTGRHCELACPPGRYGAACHL 1346
++ C +G GC H C CR+G C+ G C+ C GW G CE C G YG C
Sbjct: 315 DQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAF 374
Query: 1347 ECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
C+ + C+ +G C C PG +G C CPPG HGA C C C H CDP++G C
Sbjct: 375 VCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGAC 433
Score = 242 bits (618), Expect = 2e-63
Identities = 135/382 (35%), Positives = 158/382 (41%), Gaps = 50/382 (13%)
Query: 1106 CPAGWT--GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163
C AGW GD+C C +C C G CRC G+ G+ C+ CP
Sbjct: 64 CCAGWRQQGDECGIA--------VCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCP 114
Query: 1164 PGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ----------------RCP 1207
+G DC ++C C C TG C+C A G C+ RC
Sbjct: 115 RQFWGPDCKELCSCHPHGQ-CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCE 173
Query: 1208 PGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCP---------QGR----- 1253
PG +G C C C CD TGAC C G+ G CN C GR
Sbjct: 174 PGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRE 233
Query: 1254 --FGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS-CRNG 1310
FG C C C +G C PV GTC C PG G C CP +G+GC C C+
Sbjct: 234 RTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQ 292
Query: 1311 GLCHASNGSC-SCGLGWTGRHCELACPPGRYGAACHLECS-CHNNSTCEPATGTC-RCGP 1367
C + G C +C GW G C+ C G YG C C C + C TG C RC
Sbjct: 293 QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNA 352
Query: 1368 GFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFG 1427
G+ G CE C G +G C +C CD SGRCLC G HG C C PG G
Sbjct: 353 GWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHG 412
Query: 1428 EGCHQRCDCDGGAPCDPVTGLC 1449
C Q C C CDPVTG C
Sbjct: 413 ADCAQACSCHEDT-CDPVTGAC 433
Score = 225 bits (574), Expect = 2e-58
Identities = 124/370 (33%), Positives = 158/370 (42%), Gaps = 49/370 (13%)
Query: 517 GHDCSLTCDDCRNGGTC-----LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQ 571
G +C + C TC + C C G+ G C+ CP +G +C CSC
Sbjct: 72 GDECGIAV--CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCH 129
Query: 572 NGGTCDSVTGACRCPPGVSGTNCEDG----------------CPKGYYGKHCRKKCNCAN 615
G C+ VTG C C G CE C G++G C C C+
Sbjct: 130 PHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSA 189
Query: 616 RGRCHRLYGACLCDPGLYGRFCH----------------LTCPPWAFGPGCSEECQCVQP 659
RC GACLC G +GR C+ C FG C CQC +
Sbjct: 190 TSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG 249
Query: 660 HTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQAC-TCPVGVACDSVSGECGKRC 718
C DG+C+C+ G+RG+ C+ C G++G GC + C C C G C C
Sbjct: 250 R---CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRC-LTC 305
Query: 719 PAGFQGEDCGQECPVGTFGVNCSSSC-SC-GGAPCHGVTGQC-RCPPGRTGEDCEADCPE 775
G+ G C Q C G +G CS C C G C+ VTG+C RC G G+ CE C
Sbjct: 306 EPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSN 365
Query: 776 GRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAND 835
G +G C +C C + CD ++G CLC PG G C CP G +G C CSC D
Sbjct: 366 GTYGEDCAFVCADC-GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHED 424
Query: 836 GHCHPATGHC 845
C P TG C
Sbjct: 425 -TCDPVTGAC 433
Score = 224 bits (572), Expect = 4e-58
Identities = 127/364 (34%), Positives = 154/364 (42%), Gaps = 50/364 (13%)
Query: 1179 GENPACHPATGTCSCAAGYH--GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRC 1236
G N P + +C AG+ G C CE C C G CRC
Sbjct: 50 GRNVCRAPGSQVPTCCAGWRQQGDECGIAV--------CEGNSTCSENEVC-VRPGECRC 100
Query: 1237 PTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNR 1296
G+ G +C+ CP+ +GP+C +C C C+ VTG C C R G RCE C
Sbjct: 101 RHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQH 160
Query: 1297 ----------------FGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACP---- 1336
+G C C C C G+C C GW GR C C
Sbjct: 161 GTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSS 220
Query: 1337 -----PGR-------YGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHG 1384
GR +GA C C C C P GTC C PG+ G+ C PCP GF+G
Sbjct: 221 PCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYG 279
Query: 1385 AGCQGLCW-CQHGAPCDPISGRCL-CPAGFHGHFCERGCEPGSFGEGCHQRCD-CDGGAP 1441
GC+ C C+ PC GRCL C G++G C++ C G +GEGC RC C G
Sbjct: 280 LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHA 339
Query: 1442 CDPVTGLCL-CPPGRSGATCNLDCRRGQFGPSCTLHC-DCGGGADCDPVSGQCHCVDGYM 1499
C+ VTG C C G G C C G +G C C DCG G CD SG+C C G
Sbjct: 340 CNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSG-HCDFQSGRCLCSPGVH 398
Query: 1500 GPTC 1503
GP C
Sbjct: 399 GPHC 402
Score = 142 bits (357), Expect = 3e-33
Identities = 127/505 (25%), Positives = 180/505 (35%), Gaps = 127/505 (25%)
Query: 180 PGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDG 239
PGS + C G+R D I C GN C + ++ + C+CR G+ G
Sbjct: 57 PGSQVPTCCAGWRQQGDE---CGIAVCE-GNSTCSEN--EVCVRPGECRCRHGYF----G 106
Query: 240 RHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG 299
+C + P C C CH Q CEDV
Sbjct: 107 ANCDTKCPRQFWGPDCKELCS---------CHPHGQ-------CEDV------------- 137
Query: 300 CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPR 359
+ +C CHA G +C ++C+ C HG H +G C C
Sbjct: 138 ------TGQCTCHARRW----GARCE-------HACQ-----CQHGTCHPRSGA-CRCEP 174
Query: 360 GYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 419
G+ CA + C +P C C+AG+ G C + +CA +
Sbjct: 175 GWW----------GAQCASACYCSATSRCDPQTGACLCHAGWW----GRSCNN--QCACN 218
Query: 420 RGGCEHH---CTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAV 476
CE C +F C+ + R C P++
Sbjct: 219 SSPCEQQSGRCQCRERTFGARCDRYCQCFRGR--CHPVD--------------------- 255
Query: 477 LQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLG 536
G E RG++ + C +G C C C+ C +
Sbjct: 256 --------------GTCACEPGYRGKYC---REPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
Query: 537 LDGC-DCPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGTCDSVTGAC-RCPPGVSGTN 593
C C GW G C++ C +G+ CS C C++G C+ VTG C RC G G
Sbjct: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
Query: 594 CEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEE 653
CE C G YG+ C C G C G CLC PG++G C++TCPP G C++
Sbjct: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418
Query: 654 CQCVQPHTQSCDKRDGSCSCKAGFR 678
C C H +CD G+C + R
Sbjct: 419 CSC---HEDTCDPVTGACHLETNQR 440
Score = 130 bits (328), Expect = 8e-30
Identities = 77/236 (32%), Positives = 93/236 (39%), Gaps = 45/236 (19%)
Query: 1308 RNGGLCHASNGSC-SCGLGWT--GRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCR 1364
R +C A +C GW G C +A C +C N C G CR
Sbjct: 49 RGRNVCRAPGSQVPTCCAGWRQQGDECGIA--------VCEGNSTCSENEVCV-RPGECR 99
Query: 1365 CGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGC--- 1421
C G++G C+ CP F G C+ LC C C+ ++G+C C A G CE C
Sbjct: 100 CRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQ 159
Query: 1422 -------------EPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCN------- 1461
EPG +G C C C + CDP TG CLC G G +CN
Sbjct: 160 HGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNS 219
Query: 1462 ---------LDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1508
CR FG C +C C G C PV G C C GY G CRE P
Sbjct: 220 SPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCP 274
Score = 75.1 bits (183), Expect = 5e-13
Identities = 107/413 (25%), Positives = 131/413 (31%), Gaps = 89/413 (21%)
Query: 97 RQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCV-PGSAQPCH------- 148
R V V CC GW QQ DE G E S C CV PG + H
Sbjct: 51 RNVCRAPGSQVPTCCAGWRQQGDECGIAVCE-GNSTCSENEVCVRPGECRCRHGYFGANC 109
Query: 149 ---CPPGFQGPRCQYDVDECRTH-----------------NGGCQHRC-----VNTPGSY 183
CP F GP C+ ++ C H C+H C P S
Sbjct: 110 DTKCPRQFWGPDCK-ELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSG 168
Query: 184 LCECKPGF--RLHTDSRTCLAINSCALGNGGCQHHCVQL-TITRHRCQCRPGFQLQEDGR 240
C C+PG+ + C A + C G C H ++C C Q+ GR
Sbjct: 169 ACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGR 228
Query: 241 HCVRRSPCANRNGSCMHRCQVVRGLAR-----CECHVGYQLAADGKACEDVDECAAGL-- 293
R R C CQ RG C C GY+ GK C + C AG
Sbjct: 229 CQCRERTFGAR---CDRYCQCFRGRCHPVDGTCACEPGYR----GKYCR--EPCPAGFYG 279
Query: 294 AQCAHGCLNTQGSFKCVCHAG----YELGADGRQCYRIEMEIVNSCEAN--NGGCSHGCS 347
C C +G C G E G +G +C + C GCSH C
Sbjct: 280 LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQ-------PCATGFYGEGCSHRCP 332
Query: 348 HTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADG 407
G C G C + C+ C+N G +C + AD
Sbjct: 333 PCRDGHACNHVTG--------KCTRCNAGWIGDRCETKCSNGTYGEDCAF-----VCAD- 378
Query: 408 CGCEDVD----ECASSRGGCEHHC--TNLAGSFQCSCEAGYRLHEDRRGCSPL 454
CG D C S G HC T G C HED C P+
Sbjct: 379 CGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDT--CDPV 429
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 249 bits (637), Expect = 1e-65
Identities = 141/408 (34%), Positives = 182/408 (44%), Gaps = 65/408 (15%)
Query: 107 VLRCCRGWMQQPDEEGCLSAECSA-------SLCFHGGRCVPGSAQPCHCPPGF----QG 155
V RC +G++ D+ C + A LC + VPGS C C G+ G
Sbjct: 261 VCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVN----VPGSFV-CQCYSGYALAEDG 315
Query: 156 PRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH 215
RC VD C + N GC+H CVN GSYLC+C GF L+ D +TC I+ CA N GCQH
Sbjct: 316 KRC-VAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQH 374
Query: 216 HCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQ 275
CV T + C C GF L D + C R + CA C H C + C CH GY
Sbjct: 375 ECVN-TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYT 433
Query: 276 LAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSC 335
L +GK C VD CA C CLNT+ SF C C G+ + D + C R++ C
Sbjct: 434 LDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDY-----C 488
Query: 336 EANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA--DSPC------------ 381
++ GC + C + C CP G+ L +D +TC +D CA D C
Sbjct: 489 LLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFV 548
Query: 382 ----------------------------CQQVCTNNPGGYECGCYAGYRLSADGCGCEDV 413
C+ +C N+ Y C C G+RL+ DG C
Sbjct: 549 CQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRK 608
Query: 414 DECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDL 461
D C S+ GCEH C N S+ C C G+ L ED R C E +DL
Sbjct: 609 DVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDL 656
Score = 239 bits (610), Expect = 2e-62
Identities = 143/446 (32%), Positives = 198/446 (44%), Gaps = 44/446 (9%)
Query: 165 CRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITR 224
C T C H C+N PGSY+C CK G+ L++D TC + CA+ + C+ CV + +
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS- 300
Query: 225 HRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE 284
CQC G+ L EDG+ CV CA+ N C H C G C+CH G+ L D K C
Sbjct: 301 FVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCT 360
Query: 285 DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 344
+D CA+ C H C+NT S+ C C G+ L D + C RI N C N GC H
Sbjct: 361 KIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRI-----NYCALNKPGCEH 415
Query: 345 GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP-CCQQVCTNNPGGYECGCYAGYRL 403
C + C C RGY LD + +TC VD CA C+Q+C N + C C G+ +
Sbjct: 416 ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLI 475
Query: 404 SADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDG 463
+ D C VD C S GCE+ C N+ SF C C G+ L D + C+ L+ + G
Sbjct: 476 NEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHG 535
Query: 464 ELPFVRPLPHIAVLQDE--LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCS 521
H V ++ + Q F+ + D + T K VC + H C
Sbjct: 536 -------CEHSCVSSEDSFVCQCFEGYILREDGK--------TCRRKDVC--QAIDHGCE 578
Query: 522 LTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCS--CQNGGTCDSV 579
C + + T C+C EG+ + C K+ C C N G
Sbjct: 579 HICVNSDDSYT-------CECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGN---- 627
Query: 580 TGACRCPPGV----SGTNCEDGCPKG 601
+ C+C G G C+ C +G
Sbjct: 628 SYICKCSEGFVLAEDGRRCKK-CTEG 652
Score = 97.8 bits (242), Expect = 7e-20
Identities = 127/514 (24%), Positives = 160/514 (31%), Gaps = 137/514 (26%)
Query: 382 CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 441
C C N PG Y C C GY L++D C D CA CE C N+ GSF C C +G
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSG 308
Query: 442 YRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRG 501
Y L ED + C +AV
Sbjct: 309 YALAEDGKRC----------------------VAV------------------------- 321
Query: 502 EHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFG 561
++ +E C + D S C C G L D C + N C +
Sbjct: 322 DYCASENHGCEHECVNADGSYLCQ-CHEGFA--LNPDKKTCTKIDYCASSNHGCQHECVN 378
Query: 562 KNCSFSCSCQNGGTCDSVTGACR----CPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRG 617
+ S+SC C G T + CR C G CE C +CR
Sbjct: 379 TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPG--CEHECVNMEESYYCR--------- 427
Query: 618 RCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH---TQSCDKRDGS--CS 672
CHR Y DP G CS C Q Q C + S C
Sbjct: 428 -CHRGY---TLDPN---------------GKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQ 468
Query: 673 CKAGF----------RGERCQAE---CELGYFGPGCWQACTCPVGVACDSVSGECGKRCP 719
C GF R + C CE AC CP G S C K
Sbjct: 469 CSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKL-- 526
Query: 720 AGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
C +G G S S C G G+T +
Sbjct: 527 ---------DSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDV-------- 569
Query: 780 LGCQEICPACQHAARCDPETGACLCLPGF----VGSRC--QDVCPAGWYGPSCQTRCSCA 833
CQ I C+H ++ C CL GF G RC +DVC + +G C+ C
Sbjct: 570 --CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHG--CEH--ICV 623
Query: 834 NDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP 867
N+G+ + C C+ G+ R C GP
Sbjct: 624 NNGNSY----ICKCSEGFVLAEDGRRCKKCTEGP 653
Score = 68.6 bits (166), Expect = 5e-11
Identities = 107/457 (23%), Positives = 155/457 (33%), Gaps = 99/457 (21%)
Query: 920 QHGAA--CDHVSGA--CTCPAGW----RGTFCEHACPAGFFGLDCRSAC-NCTAGAACDA 970
+H A C ++ G+ C C G+ T C +C C N C
Sbjct: 246 EHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQC 305
Query: 971 VNGSCLCPAGRRGPRCAETCPAHTYG--HNCSQA-----CACFNGASCDPVHGQCHCAPG 1023
+G L G+R + C + +G H C A C C G + +P C
Sbjct: 306 YSGYALAEDGKRCV-AVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTC----- 359
Query: 1024 WMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRA 1083
+ + C + +G C+H C+ T D S C C +G+ +K C R +
Sbjct: 360 ----TKIDYCASSNHG--CQHECV----NTDDSYS--CHCLKGFTLNPDKKTC--RRINY 405
Query: 1084 GCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR-CSCPPGAACHH 1142
+ GC + + + C C G+T D C R + CAQ+ C
Sbjct: 406 CALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSR---VDHCAQQDHGCEQLCLNTE 462
Query: 1143 VTGACRCPPGF-----------------TGSGCEQACPPGSFGEDCAQMCQCPGENPACH 1185
+ C+C GF + GCE +C D + CQCP E
Sbjct: 463 DSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSC----VNMDRSFACQCP-EGHVLR 517
Query: 1186 PATGTC----SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
TC SCA G H GCE C + C+C G++
Sbjct: 518 SDGKTCAKLDSCALGDH---------------GCEHSC------VSSEDSFVCQCFEGYI 556
Query: 1242 GTDCNLTCPQ----GRFGPNCTHVC-GCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNR 1296
+ TC + C H+C C+ + G L G+ RC R
Sbjct: 557 LREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGK---RCRRKDVCKS 613
Query: 1297 FGVGCEHTC-SCRNGGLCHASNGSCSCGLGWTGRHCE 1332
GCEH C + N +C S G L GR C+
Sbjct: 614 THHGCEHICVNNGNSYICKCSEGFV---LAEDGRRCK 647
Score = 65.9 bits (159), Expect = 3e-10
Identities = 118/516 (22%), Positives = 165/516 (31%), Gaps = 145/516 (28%)
Query: 782 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPA 841
C + C H P + C C G++ + Q +C+ + CA + H
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQ---------TTCRIQDLCAMEDH---- 288
Query: 842 TGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCE 901
+C C G C SG L E G +
Sbjct: 289 --------------------------NCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVD 322
Query: 902 QQCPQGHFGPGCEQR---------CQCQHGAACDHVSGACT----CPAGWRGTFCEHACP 948
+ H GCE CQC G A + CT C + G C+H C
Sbjct: 323 YCASENH---GCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG--CQHEC- 376
Query: 949 AGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNC-----SQAC 1003
D +C+C G + +C RR CA P H C S C
Sbjct: 377 ---VNTDDSYSCHCLKGFTLNPDKKTC-----RRINYCALNKPG--CEHECVNMEESYYC 426
Query: 1004 ACFNGASCDPVHGQC----HCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSG 1059
C G + DP C HCA G C Q C N S +CQ
Sbjct: 427 RCHRGYTLDPNGKTCSRVDHCAQQDHG--CEQLCL------NTEDSFVCQ---------- 468
Query: 1060 HCACPEGWAGLACEKECLPRDV----RAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKC 1115
C EG+ K C D GC +S C+N + C CP G
Sbjct: 469 ---CSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVN----MDRSFACQCPEGHV---- 515
Query: 1116 QSPCLRGWFGEACAQRCSCPPG-AACHHV------TGACRCPPGF----TGSGCEQACPP 1164
LR G+ CA+ SC G C H + C+C G+ G C +
Sbjct: 516 ----LRS-DGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570
Query: 1165 GSFGEDCAQMCQCPGENPACHPATGTCSCAAGYH----GPSCQQRCPPGRYGPGCEQLCG 1220
+ C +C + + TC C G+ G C+++ GCE +
Sbjct: 571 QAIDHGCEHICVNSDD-------SYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHI-- 621
Query: 1221 CLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGP 1256
C+N G+ + C+C GF+ + C + GP
Sbjct: 622 CVNNGN----SYICKCSEGFVLAEDGRRCKKCTEGP 653
Score = 55.1 bits (131), Expect = 5e-07
Identities = 104/427 (24%), Positives = 132/427 (30%), Gaps = 101/427 (23%)
Query: 565 SFSCSCQNGGTCDSVTGACRCPP--GVSGTNCED-----------GCPKGYY----GKHC 607
S+ C C+ G +S CR + NCE C GY GK C
Sbjct: 259 SYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC 318
Query: 608 RKKCNCA--NRGRCHRLYGA-----CLCDPGLYGRFCHLTCPPWAF----GPGCSEEC-- 654
CA N G H A C C G TC + GC EC
Sbjct: 319 VAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVN 378
Query: 655 -------QCVQPHTQSCDKRDGSCSCKAGFRGERCQAEC---ELGYFGPGCWQACTCPVG 704
C++ T + DK+ C+ EC E Y+ C C G
Sbjct: 379 TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYY-------CRCHRG 431
Query: 705 VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG-GAPCHGVTGQCR---- 759
D C + Q C Q C S C C G + C
Sbjct: 432 YTLDPNGKTCSRVDHCAQQDHGCEQLC----LNTEDSFVCQCSEGFLINEDLKTCSRVDY 487
Query: 760 CPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPA 819
C G CE C CQ CP H R D +T A L D C
Sbjct: 488 CLLSDHG--CEYSCVNMDRSFACQ--CPE-GHVLRSDGKTCAKL-----------DSCAL 531
Query: 820 GWYGPSCQTRCSCANDGHCHPATGHCSCAPGWT----GFSCQR--ACDTGHWGPDCSHPC 873
G +G C+ C + D C C G+ G +C+R C G C H C
Sbjct: 532 GDHG--CEHSCVSSEDSFV------CQCFEGYILREDGKTCRRKDVCQAIDHG--CEHIC 581
Query: 874 NCSAGHGSCDAISGLCLCEAGYVGPRCEQQ--CPQGHFGPGCEQRCQCQHGAACDHVSGA 931
S +C+ + G L E G RC ++ C H G C+H + S
Sbjct: 582 VNSDDSYTCECLEGFRLAED---GKRCRRKDVCKSTHHG--------CEHICVNNGNSYI 630
Query: 932 CTCPAGW 938
C C G+
Sbjct: 631 CKCSEGF 637
Score = 53.5 bits (127), Expect = 2e-06
Identities = 87/355 (24%), Positives = 111/355 (31%), Gaps = 82/355 (23%)
Query: 1186 PATGTCSCAAGYHGPSCQQRCPP----GRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
P + C C GY S Q C CEQLC + G C+C +G+
Sbjct: 257 PGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF------VCQCYSGYA 310
Query: 1242 ----GTDC---------NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC 1288
G C N C + +++C C +G A +P TC A
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCAS--S 368
Query: 1289 ERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCS----CGLGWTGRHCELACPPGRYGAAC 1344
GC ++C C G + +C C L G CE C
Sbjct: 369 NHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPG--CEHEC----VNMEE 422
Query: 1345 HLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISG 1404
C CH T +P TC +H C H GC+ LC S
Sbjct: 423 SYYCRCHRGYTLDPNGKTC--------SRVDH-CAQQDH--GCEQLCLNTED------SF 465
Query: 1405 RCLCPAGFHGHFCERGCEPGSF----GEGCHQRC-DCDGGAPCDPVTGLCLCPPGR---- 1455
C C GF + + C + GC C + D C CP G
Sbjct: 466 VCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQ-------CPEGHVLRS 518
Query: 1456 SGATC-NLD-CRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYM----GPTCR 1504
G TC LD C G G C S C C +GY+ G TCR
Sbjct: 519 DGKTCAKLDSCALGDHG--------CEHSCVSSEDSFVCQCFEGYILREDGKTCR 565
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 249 bits (637), Expect = 1e-65
Identities = 141/408 (34%), Positives = 182/408 (44%), Gaps = 65/408 (15%)
Query: 107 VLRCCRGWMQQPDEEGCLSAECSA-------SLCFHGGRCVPGSAQPCHCPPGF----QG 155
V RC +G++ D+ C + A LC + VPGS C C G+ G
Sbjct: 261 VCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVN----VPGSFV-CQCYSGYALAEDG 315
Query: 156 PRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH 215
RC VD C + N GC+H CVN GSYLC+C GF L+ D +TC I+ CA N GCQH
Sbjct: 316 KRC-VAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQH 374
Query: 216 HCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQ 275
CV T + C C GF L D + C R + CA C H C + C CH GY
Sbjct: 375 ECVN-TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYT 433
Query: 276 LAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSC 335
L +GK C VD CA C CLNT+ SF C C G+ + D + C R++ C
Sbjct: 434 LDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDY-----C 488
Query: 336 EANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA--DSPC------------ 381
++ GC + C + C CP G+ L +D +TC +D CA D C
Sbjct: 489 LLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFV 548
Query: 382 ----------------------------CQQVCTNNPGGYECGCYAGYRLSADGCGCEDV 413
C+ +C N+ Y C C G+RL+ DG C
Sbjct: 549 CQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRK 608
Query: 414 DECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDL 461
D C S+ GCEH C N S+ C C G+ L ED R C E +DL
Sbjct: 609 DVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDL 656
Score = 239 bits (610), Expect = 2e-62
Identities = 143/446 (32%), Positives = 198/446 (44%), Gaps = 44/446 (9%)
Query: 165 CRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITR 224
C T C H C+N PGSY+C CK G+ L++D TC + CA+ + C+ CV + +
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGS- 300
Query: 225 HRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE 284
CQC G+ L EDG+ CV CA+ N C H C G C+CH G+ L D K C
Sbjct: 301 FVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCT 360
Query: 285 DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 344
+D CA+ C H C+NT S+ C C G+ L D + C RI N C N GC H
Sbjct: 361 KIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRI-----NYCALNKPGCEH 415
Query: 345 GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP-CCQQVCTNNPGGYECGCYAGYRL 403
C + C C RGY LD + +TC VD CA C+Q+C N + C C G+ +
Sbjct: 416 ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLI 475
Query: 404 SADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDG 463
+ D C VD C S GCE+ C N+ SF C C G+ L D + C+ L+ + G
Sbjct: 476 NEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHG 535
Query: 464 ELPFVRPLPHIAVLQDE--LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCS 521
H V ++ + Q F+ + D + T K VC + H C
Sbjct: 536 -------CEHSCVSSEDSFVCQCFEGYILREDGK--------TCRRKDVC--QAIDHGCE 578
Query: 522 LTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCS--CQNGGTCDSV 579
C + + T C+C EG+ + C K+ C C N G
Sbjct: 579 HICVNSDDSYT-------CECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGN---- 627
Query: 580 TGACRCPPGV----SGTNCEDGCPKG 601
+ C+C G G C+ C +G
Sbjct: 628 SYICKCSEGFVLAEDGRRCKK-CTEG 652
Score = 97.8 bits (242), Expect = 7e-20
Identities = 127/514 (24%), Positives = 160/514 (31%), Gaps = 137/514 (26%)
Query: 382 CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 441
C C N PG Y C C GY L++D C D CA CE C N+ GSF C C +G
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSG 308
Query: 442 YRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRG 501
Y L ED + C +AV
Sbjct: 309 YALAEDGKRC----------------------VAV------------------------- 321
Query: 502 EHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFG 561
++ +E C + D S C C G L D C + N C +
Sbjct: 322 DYCASENHGCEHECVNADGSYLCQ-CHEGFA--LNPDKKTCTKIDYCASSNHGCQHECVN 378
Query: 562 KNCSFSCSCQNGGTCDSVTGACR----CPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRG 617
+ S+SC C G T + CR C G CE C +CR
Sbjct: 379 TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPG--CEHECVNMEESYYCR--------- 427
Query: 618 RCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH---TQSCDKRDGS--CS 672
CHR Y DP G CS C Q Q C + S C
Sbjct: 428 -CHRGY---TLDPN---------------GKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQ 468
Query: 673 CKAGF----------RGERCQAE---CELGYFGPGCWQACTCPVGVACDSVSGECGKRCP 719
C GF R + C CE AC CP G S C K
Sbjct: 469 CSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKL-- 526
Query: 720 AGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
C +G G S S C G G+T +
Sbjct: 527 ---------DSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDV-------- 569
Query: 780 LGCQEICPACQHAARCDPETGACLCLPGF----VGSRC--QDVCPAGWYGPSCQTRCSCA 833
CQ I C+H ++ C CL GF G RC +DVC + +G C+ C
Sbjct: 570 --CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHG--CEH--ICV 623
Query: 834 NDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP 867
N+G+ + C C+ G+ R C GP
Sbjct: 624 NNGNSY----ICKCSEGFVLAEDGRRCKKCTEGP 653
Score = 68.6 bits (166), Expect = 5e-11
Identities = 107/457 (23%), Positives = 155/457 (33%), Gaps = 99/457 (21%)
Query: 920 QHGAA--CDHVSGA--CTCPAGW----RGTFCEHACPAGFFGLDCRSAC-NCTAGAACDA 970
+H A C ++ G+ C C G+ T C +C C N C
Sbjct: 246 EHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQC 305
Query: 971 VNGSCLCPAGRRGPRCAETCPAHTYG--HNCSQA-----CACFNGASCDPVHGQCHCAPG 1023
+G L G+R + C + +G H C A C C G + +P C
Sbjct: 306 YSGYALAEDGKRCV-AVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTC----- 359
Query: 1024 WMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRA 1083
+ + C + +G C+H C+ T D S C C +G+ +K C R +
Sbjct: 360 ----TKIDYCASSNHG--CQHECV----NTDDSYS--CHCLKGFTLNPDKKTC--RRINY 405
Query: 1084 GCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR-CSCPPGAACHH 1142
+ GC + + + C C G+T D C R + CAQ+ C
Sbjct: 406 CALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSR---VDHCAQQDHGCEQLCLNTE 462
Query: 1143 VTGACRCPPGF-----------------TGSGCEQACPPGSFGEDCAQMCQCPGENPACH 1185
+ C+C GF + GCE +C D + CQCP E
Sbjct: 463 DSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSC----VNMDRSFACQCP-EGHVLR 517
Query: 1186 PATGTC----SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
TC SCA G H GCE C + C+C G++
Sbjct: 518 SDGKTCAKLDSCALGDH---------------GCEHSC------VSSEDSFVCQCFEGYI 556
Query: 1242 GTDCNLTCPQ----GRFGPNCTHVC-GCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNR 1296
+ TC + C H+C C+ + G L G+ RC R
Sbjct: 557 LREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGK---RCRRKDVCKS 613
Query: 1297 FGVGCEHTC-SCRNGGLCHASNGSCSCGLGWTGRHCE 1332
GCEH C + N +C S G L GR C+
Sbjct: 614 THHGCEHICVNNGNSYICKCSEGFV---LAEDGRRCK 647
Score = 65.9 bits (159), Expect = 3e-10
Identities = 118/516 (22%), Positives = 165/516 (31%), Gaps = 145/516 (28%)
Query: 782 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPA 841
C + C H P + C C G++ + Q +C+ + CA + H
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQ---------TTCRIQDLCAMEDH---- 288
Query: 842 TGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCE 901
+C C G C SG L E G +
Sbjct: 289 --------------------------NCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVD 322
Query: 902 QQCPQGHFGPGCEQR---------CQCQHGAACDHVSGACT----CPAGWRGTFCEHACP 948
+ H GCE CQC G A + CT C + G C+H C
Sbjct: 323 YCASENH---GCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG--CQHEC- 376
Query: 949 AGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNC-----SQAC 1003
D +C+C G + +C RR CA P H C S C
Sbjct: 377 ---VNTDDSYSCHCLKGFTLNPDKKTC-----RRINYCALNKPG--CEHECVNMEESYYC 426
Query: 1004 ACFNGASCDPVHGQC----HCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSG 1059
C G + DP C HCA G C Q C N S +CQ
Sbjct: 427 RCHRGYTLDPNGKTCSRVDHCAQQDHG--CEQLCL------NTEDSFVCQ---------- 468
Query: 1060 HCACPEGWAGLACEKECLPRDV----RAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKC 1115
C EG+ K C D GC +S C+N + C CP G
Sbjct: 469 ---CSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVN----MDRSFACQCPEGHV---- 515
Query: 1116 QSPCLRGWFGEACAQRCSCPPG-AACHHV------TGACRCPPGF----TGSGCEQACPP 1164
LR G+ CA+ SC G C H + C+C G+ G C +
Sbjct: 516 ----LRS-DGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570
Query: 1165 GSFGEDCAQMCQCPGENPACHPATGTCSCAAGYH----GPSCQQRCPPGRYGPGCEQLCG 1220
+ C +C + + TC C G+ G C+++ GCE +
Sbjct: 571 QAIDHGCEHICVNSDD-------SYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHI-- 621
Query: 1221 CLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGP 1256
C+N G+ + C+C GF+ + C + GP
Sbjct: 622 CVNNGN----SYICKCSEGFVLAEDGRRCKKCTEGP 653
Score = 55.1 bits (131), Expect = 5e-07
Identities = 104/427 (24%), Positives = 132/427 (30%), Gaps = 101/427 (23%)
Query: 565 SFSCSCQNGGTCDSVTGACRCPP--GVSGTNCED-----------GCPKGYY----GKHC 607
S+ C C+ G +S CR + NCE C GY GK C
Sbjct: 259 SYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC 318
Query: 608 RKKCNCA--NRGRCHRLYGA-----CLCDPGLYGRFCHLTCPPWAF----GPGCSEEC-- 654
CA N G H A C C G TC + GC EC
Sbjct: 319 VAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVN 378
Query: 655 -------QCVQPHTQSCDKRDGSCSCKAGFRGERCQAEC---ELGYFGPGCWQACTCPVG 704
C++ T + DK+ C+ EC E Y+ C C G
Sbjct: 379 TDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYY-------CRCHRG 431
Query: 705 VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG-GAPCHGVTGQCR---- 759
D C + Q C Q C S C C G + C
Sbjct: 432 YTLDPNGKTCSRVDHCAQQDHGCEQLC----LNTEDSFVCQCSEGFLINEDLKTCSRVDY 487
Query: 760 CPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPA 819
C G CE C CQ CP H R D +T A L D C
Sbjct: 488 CLLSDHG--CEYSCVNMDRSFACQ--CPE-GHVLRSDGKTCAKL-----------DSCAL 531
Query: 820 GWYGPSCQTRCSCANDGHCHPATGHCSCAPGWT----GFSCQR--ACDTGHWGPDCSHPC 873
G +G C+ C + D C C G+ G +C+R C G C H C
Sbjct: 532 GDHG--CEHSCVSSEDSFV------CQCFEGYILREDGKTCRRKDVCQAIDHG--CEHIC 581
Query: 874 NCSAGHGSCDAISGLCLCEAGYVGPRCEQQ--CPQGHFGPGCEQRCQCQHGAACDHVSGA 931
S +C+ + G L E G RC ++ C H G C+H + S
Sbjct: 582 VNSDDSYTCECLEGFRLAED---GKRCRRKDVCKSTHHG--------CEHICVNNGNSYI 630
Query: 932 CTCPAGW 938
C C G+
Sbjct: 631 CKCSEGF 637
Score = 53.5 bits (127), Expect = 2e-06
Identities = 87/355 (24%), Positives = 111/355 (31%), Gaps = 82/355 (23%)
Query: 1186 PATGTCSCAAGYHGPSCQQRCPP----GRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
P + C C GY S Q C CEQLC + G C+C +G+
Sbjct: 257 PGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSF------VCQCYSGYA 310
Query: 1242 ----GTDC---------NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC 1288
G C N C + +++C C +G A +P TC A
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCAS--S 368
Query: 1289 ERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCS----CGLGWTGRHCELACPPGRYGAAC 1344
GC ++C C G + +C C L G CE C
Sbjct: 369 NHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPG--CEHEC----VNMEE 422
Query: 1345 HLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISG 1404
C CH T +P TC +H C H GC+ LC S
Sbjct: 423 SYYCRCHRGYTLDPNGKTC--------SRVDH-CAQQDH--GCEQLCLNTED------SF 465
Query: 1405 RCLCPAGFHGHFCERGCEPGSF----GEGCHQRC-DCDGGAPCDPVTGLCLCPPGR---- 1455
C C GF + + C + GC C + D C CP G
Sbjct: 466 VCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQ-------CPEGHVLRS 518
Query: 1456 SGATC-NLD-CRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYM----GPTCR 1504
G TC LD C G G C S C C +GY+ G TCR
Sbjct: 519 DGKTCAKLDSCALGDHG--------CEHSCVSSEDSFVCQCFEGYILREDGKTCR 565
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 249 bits (636), Expect = 1e-65
Identities = 126/331 (38%), Positives = 171/331 (51%), Gaps = 37/331 (11%)
Query: 147 CHCPPGFQGP--RCQYDVDECRTH-NGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAI 203
C C PG+QG +C+ D+DEC NGGC H C+N PG+Y C C GF L D CL +
Sbjct: 71 CSCKPGYQGEGRQCE-DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDV 129
Query: 204 NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRS----PCANRNGSCMHRC 259
+ C NGGCQH CV + + + C C+ GF L ++ C+ RS C N++ C H C
Sbjct: 130 DECLENNGGCQHTCVNV-MGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHIC 188
Query: 260 -QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELG 318
+ RG CEC G++LA + + C + C G C H C +T +C CH Y++
Sbjct: 189 KEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKMH 246
Query: 319 ADGRQCYRIE---MEIVNS--------------------CEANNGGCSHGCSHTSAGPLC 355
DGR C E +E+ S C NNGGC C TS G C
Sbjct: 247 TDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHC 306
Query: 356 TCPRGYELDTDQRTCIDVDDC-ADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVD 414
+CP G+ L D +TC D+D+C + C C N G ++CGC G++L D C+DVD
Sbjct: 307 SCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVD 366
Query: 415 ECASSRGGCEHHCTNLAGSFQCSCEAGYRLH 445
EC+ R C+H C N G+F C+C GY L+
Sbjct: 367 ECSLDR-TCDHSCINHPGTFACACNRGYTLY 396
Score = 240 bits (612), Expect = 9e-63
Identities = 131/379 (34%), Positives = 180/379 (47%), Gaps = 56/379 (14%)
Query: 127 ECSASL---CFHGGRCVPGSAQPCHCPPGFQ----GPRCQYDVDECRTHNGGCQHRCVNT 179
EC L C H +PG+ + C C GF G C DVDEC +NGGCQH CVN
Sbjct: 89 ECGNELNGGCVHDCLNIPGNYR-CTCFDGFMLAHDGHNC-LDVDECLENNGGCQHTCVNV 146
Query: 180 PGSYLCECKPGFRLHTDSRTCLAIN----SCALGNGGCQHHCVQLTITRHRCQCRPGFQL 235
GSY C CK GF L + TC+ + SC + GC H C + C+CRPGF+L
Sbjct: 147 MGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFEL 206
Query: 236 QEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKAC---ED------- 285
++ R C+ C + NG C H C C CH Y++ DG++C ED
Sbjct: 207 AKNQRDCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTE 264
Query: 286 ------------------VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRI 327
++ CA C C +T C C G+ L DG+ C I
Sbjct: 265 SNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDI 324
Query: 328 EMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCT 387
+ C+ NGGC H C + C C +G++L TD+++C DVD+C+ C C
Sbjct: 325 D-----ECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI 379
Query: 388 NNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED 447
N+PG + C C GY L C D +EC+ + GGC+ C N GS++C C GY+LH +
Sbjct: 380 NHPGTFACACNRGYTLYG-FTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWN 438
Query: 448 RRGCSPLEEPMVDLDGELP 466
++ C V++ G LP
Sbjct: 439 KKDC-------VEVKGLLP 450
Score = 217 bits (552), Expect = 8e-56
Identities = 119/351 (33%), Positives = 162/351 (46%), Gaps = 52/351 (14%)
Query: 150 PPG---FQGPRCQYDVDECRTHNGGCQHR--CVNTPGSYLCECKPGFRLHTDSRTCLAIN 204
PPG GP Q DVDEC C C NTP SY C CKPG++ + R C I+
Sbjct: 33 PPGRGRAAGP--QEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDID 88
Query: 205 SCALG-NGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVR 263
C NGGC H C+ + +RC C GF L DG +C+ C NG C H C V
Sbjct: 89 ECGNELNGGCVHDCLNIP-GNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVM 147
Query: 264 GLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNT-----QGSFKCVCHAGYELG 318
G C C G+ L+ + C E HGC + +GS C C G+EL
Sbjct: 148 GSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELA 207
Query: 319 ADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDD--- 375
+ R C + +C NGGC H C T+ GP C+C Y++ TD R+C++ +D
Sbjct: 208 KNQRDC-------ILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVL 260
Query: 376 -------------------------CA-DSPCCQQVCTNNPGGYECGCYAGYRLSADGCG 409
CA ++ C + C + G C C G+ L DG
Sbjct: 261 EVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKT 320
Query: 410 CEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVD 460
C+D+DEC + GGC+H C N+ GSF C C+ G++L D + C ++E +D
Sbjct: 321 CKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLD 371
Score = 157 bits (398), Expect = 6e-38
Identities = 127/495 (25%), Positives = 184/495 (37%), Gaps = 98/495 (19%)
Query: 259 CQVVRGLARCECHVGYQLAADGKACEDVDECAAGL-AQCAHGCLNTQGSFKCVCHAGYEL 317
CQ +C C GYQ +G+ CED+DEC L C H CLN G+++C C G+ L
Sbjct: 62 CQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFML 119
Query: 318 GADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDD-- 375
DG C ++ C NNGGC H C + C C G+ L +Q TCI +
Sbjct: 120 AHDGHNCLDVD-----ECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEG 174
Query: 376 --CADSPC-CQQVCTNNP-GGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLA 431
C + C +C P G C C G+ L+ + C + C GGC+H C + A
Sbjct: 175 LSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDDTA 232
Query: 432 GSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVG 491
+CSC Y++H D R C E+ +++ V
Sbjct: 233 DGPECSCHPQYKMHTDGRSCLEREDTVLE-----------------------------VT 263
Query: 492 ADEEEAELRGEHTLTEKFV---CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTG 548
+ + G+ + + + C ++ G C TC D G C CP G+T
Sbjct: 264 ESNTTSVVDGDKRVKRRLLMETCAVNNGG--CDRTCKDTSTGVHC-------SCPVGFTL 314
Query: 549 LICNETCPPDTFGKNCSFSCSCQNGGT---CDSVTGACRCPPGVSGTNCEDGCPKGYY-- 603
+ +TC C +NGG C ++ G+ C GC KG+
Sbjct: 315 QLDGKTCKDID-------ECQTRNGGCDHFCKNIVGSFDC-----------GCKKGFKLL 356
Query: 604 --GKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHT 661
K C+ C+ C +C+ PG + C+ + F C + T
Sbjct: 357 TDEKSCQDVDECSLDRTCDH---SCINHPGTFACACNRGYTLYGF-THCGD--------T 404
Query: 662 QSCDKRDGSCS--CKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCP 719
C +G C C CQ C GY + C G+ SVS C
Sbjct: 405 NECSINNGGCQQVCVNTVGSYECQ--CHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLHCG 462
Query: 720 AGFQGEDCGQECPVG 734
G+ C C G
Sbjct: 463 KSGGGDGCFLRCHSG 477
Score = 71.6 bits (174), Expect = 5e-12
Identities = 112/457 (24%), Positives = 149/457 (32%), Gaps = 107/457 (23%)
Query: 832 CANDGHCH--PATGHCSCAPGW--TGFSCQRACDTGH-WGPDCSHPCNCSAGHGSCDAIS 886
C D C P + CSC PG+ G C+ + G+ C H C G+ C
Sbjct: 56 CHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFD 115
Query: 887 GLCLCEAGYVGPRC--EQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCE 944
G L G+ C +C + + G CQH C +V G+ C
Sbjct: 116 GFMLAHDGH---NCLDVDECLENNGG--------CQH--TCVNVMGSYEC---------- 152
Query: 945 HACPAGFFGLDCRSAC--NCTAGAACDAVNGSC--LCPAGRRGPRCAETCPAHTYGHN-- 998
C GFF D + C G +C + C +C RG E P N
Sbjct: 153 -CCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 999 -CSQACACFNGA---SCDPVHG--QCHCAPGWM----GPSCLQA-----------CPAGL 1037
C C NG SCD +C C P + G SCL+ + +
Sbjct: 212 DCILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVV 271
Query: 1038 YGDN------CRHSCLCQNGG---TCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCR 1086
GD +C NGG TC S HC+CP G+ K C +D+
Sbjct: 272 DGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTC--KDIDECQT 329
Query: 1087 HSGGCLNGGLCDPHTGR--CLCPAGW---TGDK-CQSPCLRGWFGEACAQRCSCPPGAAC 1140
+GGC C G C C G+ T +K CQ + C+ +C
Sbjct: 330 RNGGC--DHFCKNIVGSFDCGCKKGFKLLTDEKSCQDV-------DECSLDRTCDHSCIN 380
Query: 1141 HHVTGACRCPPGFT----------------GSGCEQAC--PPGSFGEDCAQMCQCPGENP 1182
H T AC C G+T GC+Q C GS+ C +
Sbjct: 381 HPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKK 440
Query: 1183 ACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLC 1219
C G + P C G GC C
Sbjct: 441 DCVEVKGLLPTSV---SPRVSLHCGKSGGGDGCFLRC 474
Score = 71.2 bits (173), Expect = 7e-12
Identities = 128/497 (25%), Positives = 154/497 (30%), Gaps = 122/497 (24%)
Query: 1033 CPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCL 1092
C GL D+C LCQN P S C+C G+ G ++C D G +GGC+
Sbjct: 49 CAQGL--DDCHADALCQN----TPTSYKCSCKPGYQGEG--RQCEDID-ECGNELNGGCV 99
Query: 1093 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPG 1152
+ L P RC C G+ CL E C C +V G+ C
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLD--VDECLENNGGCQH--TCVNVMGSYEC--- 152
Query: 1153 FTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG 1212
C G F D C H + SC HG
Sbjct: 153 --------CCKEGFFLSDNQHTC--------IHRSEEGLSCMNKDHG------------- 183
Query: 1213 PGCEQLCGCLNGGSCDAATGACRCPTGFL----GTDCNLTCPQGRFGPNCTHVCGCGQGA 1268
C +C GS AC C GF DC LTC G G C H C
Sbjct: 184 --CSHICKEAPRGSV-----ACECRPGFELAKNQRDCILTCNHGNGG--CQHSCD----- 229
Query: 1269 ACDPVTGT-CLCPPGRAGVRCERGCPQNR---FGVGCEHTCSCRNGG----------LCH 1314
D G C C P R C + V +T S +G C
Sbjct: 230 --DTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCA 287
Query: 1315 ASNGSC--SCGLGWTGRHCELACPPGRY----GAACHL--ECSCHNNST---CEPATGTC 1363
+NG C +C TG HC +CP G G C EC N C+ G+
Sbjct: 288 VNNGGCDRTCKDTSTGVHC--SCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSF 345
Query: 1364 RCGPGFYGQACEHPCPPGFH----GAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCER 1419
CG C GF CQ + C CD C+ G C R
Sbjct: 346 DCG-----------CKKGFKLLTDEKSCQDVDECSLDRTCDH---SCINHPGTFACACNR 391
Query: 1420 GCEPGSFGE-GCHQRCDCDGGA---PCDPVTGL--CLCPPGRSGATCNLDCRRGQ----- 1468
G F G C + G C G C C PG DC +
Sbjct: 392 GYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPT 451
Query: 1469 -FGPSCTLHCDCGGGAD 1484
P +LHC GG D
Sbjct: 452 SVSPRVSLHCGKSGGGD 468
Score = 63.2 bits (152), Expect = 2e-09
Identities = 98/411 (23%), Positives = 131/411 (31%), Gaps = 87/411 (21%)
Query: 671 CSCKAGFRGE--RCQAECELG-YFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDC 727
CSCK G++GE +C+ E G GC C ++ G C GF
Sbjct: 71 CSCKPGYQGEGRQCEDIDECGNELNGGCVHDCL--------NIPGNYRCTCFDGFMLAHD 122
Query: 728 GQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPGRTGEDCEADC-PEGRWGLGCQE 784
G C + + C C V G +C C G D + C GL C
Sbjct: 123 GHNCLDVDECLENNGGCQ---HTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMN 179
Query: 785 ICPACQHAARCDPE-TGACLCLPGFVGSRCQDVC--PAGWYGPSCQTRCSCANDGHCHPA 841
C H + P + AC C PGF ++ Q C CQ C DG
Sbjct: 180 KDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADG----- 234
Query: 842 TGHCSCAPGW----TGFSCQRACDTGHWGPDCSHPC---------------NCSAGHGSC 882
CSC P + G SC DT + + C+ +G C
Sbjct: 235 -PECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGC 293
Query: 883 DAISGLCLCEAGYVGPRCEQQCPQGHF----GPGCEQRCQCQ-HGAACDHV------SGA 931
D C+ G C CP G G C+ +CQ CDH S
Sbjct: 294 DR-----TCKDTSTGVHC--SCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFD 346
Query: 932 CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCP 991
C C G++ E + C+ C+ CD SC+ G C
Sbjct: 347 CGCKKGFKLLTDEKS---------CQDVDECSLDRTCD---HSCINHPGTFACACNRGYT 394
Query: 992 AHTYGHNCSQACAC-FNGASCDPV------HGQCHCAPG----WMGPSCLQ 1031
+ + H C C N C V +C C PG W C++
Sbjct: 395 LYGFTH-CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVE 444
Score = 60.5 bits (145), Expect = 1e-08
Identities = 186/860 (21%), Positives = 254/860 (29%), Gaps = 190/860 (22%)
Query: 519 DCSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQN---G 573
+C+ DDC C C C G+ G G+ C C N G
Sbjct: 48 ECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE-----------GRQCEDIDECGNELNG 96
Query: 574 GT---CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCA-NRGRCHRLYGACLCD 629
G C ++ G RC C DG + G +C C N G C C+
Sbjct: 97 GCVHDCLNIPGNYRC-------TCFDGFMLAHDGHNCLDVDECLENNGGCQH---TCVNV 146
Query: 630 PGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCS--CKAGFRGERCQAECE 687
G Y C F C SC +D CS CK RG EC
Sbjct: 147 MGSY----ECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGS-VACECR 201
Query: 688 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG--QECPVGTFGVNC----- 740
G+ + C + C+ +G C C G +C + + T G +C
Sbjct: 202 PGFELAKNQRDCI----LTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLERED 257
Query: 741 -------SSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA 793
S++ S V G R E C + GC C
Sbjct: 258 TVLEVTESNTTSV-------VDGDKRVKRRLLMETCAVN------NGGCDRTCKDTSTGV 304
Query: 794 RCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGH--CSCAPGW 851
C G L L G C+D+ CQTR + D C G C C G+
Sbjct: 305 HCSCPVGFTLQLDG---KTCKDI-------DECQTR-NGGCDHFCKNIVGSFDCGCKKGF 353
Query: 852 TGFSCQRAC---DTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGH 908
+ +++C D C H C G +C G L + G E G
Sbjct: 354 KLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNG- 412
Query: 909 FGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC 968
GC+Q C G S C C G++ + + DC +
Sbjct: 413 ---GCQQVCVNTVG------SYECQCHPGYKLHWNKK---------DCVEVKGLLPTSVS 454
Query: 969 DAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPS 1028
V+ C G G C C H+ H S + G+C + P
Sbjct: 455 PRVSLHCGKSGG--GDGCFLRC--HSGIHLSSDVTTIRTSVTFKLNEGKCSLKNAELFPE 510
Query: 1029 CLQACPAGLYG---DNCRHSCL-CQNGGTCDPVSGHCACP-EGWAGLACEKECLPRDVRA 1083
L+ + ++ R+ L C +G G + P E + + E E ++V A
Sbjct: 511 GLRPALPEKHSSVKESFRYVNLTCSSGKQVPGAPGRPSTPKEMFITVEFELETNQKEVTA 570
Query: 1084 GC-------------------------------RHSGGCLNGGLCDPHTGR-----CLCP 1107
C + SG L+ P T C
Sbjct: 571 SCDLSCIVKRTEKRLRKAIRTLRKAVHREQFHLQLSGMNLDVAKKPPRTSERQAESCGVG 630
Query: 1108 AGWTGDKCQSPCLRGWFGEACAQRCS-CPPGA--------ACHHV-----TGACRCPPGF 1153
G ++C S C G + + +RC CP G C +GA + P +
Sbjct: 631 QGHAENQCVS-CRAGTYYDGARERCILCPNGTFQNEEGQMTCEPCPRPGNSGALKTPEAW 689
Query: 1154 TGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSC-------AAGYHGPSCQQRC 1206
S C C PG + D CQ P G SC A + G + Q
Sbjct: 690 NMSECGGLCQPGEYSADGFAPCQLCALG-TFQPEAGRTSCFPCGGGLATKHQGATSFQ-- 746
Query: 1207 PPGRYGPGCEQLCGCLNGGSCDAATGAC-RCPTGFLGTDCNLTCPQGRFGPNCTHVCGCG 1265
CE C G + T C RCP G Q FG N C
Sbjct: 747 -------DCETRVQCSPGHFYNTTTHRCIRCPVGTY---------QPEFGKNNCVSCPGN 790
Query: 1266 QGAACDPVTGTCLCPPGRAG 1285
D T C R G
Sbjct: 791 TTTDFDGSTNITQCKNRRCG 810
Score = 45.8 bits (107), Expect = 3e-04
Identities = 45/167 (26%), Positives = 59/167 (35%), Gaps = 16/167 (9%)
Query: 1262 CGCGQGAACDPVT----GTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS-CRNGGLCHAS 1316
CG GQG A + GT + C G QN G + TC C G +
Sbjct: 627 CGVGQGHAENQCVSCRAGTYYDGARERCILCPNGTFQNEEG---QMTCEPCPRPG----N 679
Query: 1317 NGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEH 1376
+G+ W C C PG Y A C T +P G C P G A +H
Sbjct: 680 SGALKTPEAWNMSECGGLCQPGEYSADGFAPCQLCALGTFQPEAGRTSCFPCGGGLATKH 739
Query: 1377 PCPPGFHGAGCQGLCWCQHGAPCDPISGRCL-CPAG-FHGHFCERGC 1421
F C+ C G + + RC+ CP G + F + C
Sbjct: 740 QGATSFQ--DCETRVQCSPGHFYNTTTHRCIRCPVGTYQPEFGKNNC 784
Score = 32.0 bits (71), Expect = 4.8
Identities = 52/217 (23%), Positives = 70/217 (32%), Gaps = 43/217 (19%)
Query: 205 SCALGNGGCQHHCVQLTI------TRHRCQCRPG--FQLQEDGRHCVRRSPCANRNGSCM 256
SC +G G ++ CV R RC P FQ +E C PC S
Sbjct: 626 SCGVGQGHAENQCVSCRAGTYYDGARERCILCPNGTFQNEEGQMTC---EPCPRPGNSGA 682
Query: 257 HRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNT----QGSFKCV-C 311
+ ++ C G C+ + A G A C L T G C C
Sbjct: 683 LKTPEAWNMSEC-----------GGLCQPGEYSADGFAPCQLCALGTFQPEAGRTSCFPC 731
Query: 312 HAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC-TCPRG-YELDTDQRT 369
G G ++ CE CS G + + C CP G Y+ + +
Sbjct: 732 GGGLATKHQGATSFQ-------DCE-TRVQCSPGHFYNTTTHRCIRCPVGTYQPEFGKNN 783
Query: 370 CID-----VDDCADSPCCQQVCTNNPGGYECGCYAGY 401
C+ D S Q C N G E G + GY
Sbjct: 784 CVSCPGNTTTDFDGSTNITQ-CKNRRCGGELGDFTGY 819
Score = 31.2 bits (69), Expect = 8.1
Identities = 48/226 (21%), Positives = 69/226 (30%), Gaps = 39/226 (17%)
Query: 873 CNCSAGHGSCDAISGLCLCEAGYVGPRCEQQC---PQGHFGPGCEQRCQCQHGAACDHVS 929
C GH +S C AG ++C P G F E + C+ + S
Sbjct: 627 CGVGQGHAENQCVS----CRAGTYYDGARERCILCPNGTF-QNEEGQMTCEPCPRPGN-S 680
Query: 930 GACTCPAGWRGTFCEHACPAGFFGLDCRSACN-CTAGAACDAVNGSCLCPAG------RR 982
GA P W + C C G + D + C C G + P G +
Sbjct: 681 GALKTPEAWNMSECGGLCQPGEYSADGFAPCQLCALGTFQPEAGRTSCFPCGGGLATKHQ 740
Query: 983 GPRCAETC-------PAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPA 1035
G + C P H Y + C G + P G+ +C +CP
Sbjct: 741 GATSFQDCETRVQCSPGHFYNTTTHRCIRCPVG-TYQPEFGKNNCV----------SCPG 789
Query: 1036 GLYG--DNCRHSCLCQN---GGTCDPVSGHCACPEGWAGLACEKEC 1076
D + C+N GG +G+ P EC
Sbjct: 790 NTTTDFDGSTNITQCKNRRCGGELGDFTGYIESPNYPGNYPANTEC 835
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 248 bits (634), Expect = 2e-65
Identities = 125/327 (38%), Positives = 169/327 (51%), Gaps = 20/327 (6%)
Query: 133 CFHGGRCVPGSAQPCHCPPGFQ----GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECK 188
C H +PG+ + C C GF G C DVDEC+ +NGGCQ CVN GSY C+C
Sbjct: 87 CVHECINIPGNYR-CTCFDGFMLAHDGHNC-LDVDECQDNNGGCQQICVNAMGSYECQCH 144
Query: 189 PGFRLHTDSRTCLAINS----CALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVR 244
GF L + TC+ ++ C + GC H C + C CRPGF L ++ + C
Sbjct: 145 SGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTL 204
Query: 245 RSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQ 304
C NG C H C+ C CH Y L +DG+ C ++ CA C C +T
Sbjct: 205 T--CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDRTCKDTA 260
Query: 305 GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELD 364
+C C G+ L DG+ C + +N C NNGGC H C +T C C +GY+L
Sbjct: 261 TGVRCSCPVGFTLQPDGKTC-----KDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLL 315
Query: 365 TDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCE 424
TD+RTC D+D+C+ C +C N+PG ++C C+ GY L C DVDEC+ S G C+
Sbjct: 316 TDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGT-THCGDVDECSMSNGSCD 374
Query: 425 HHCTNLAGSFQCSCEAGYRLHEDRRGC 451
C N GS++C C G RLH + + C
Sbjct: 375 QGCVNTKGSYECVCPPGRRLHWNGKDC 401
Score = 228 bits (580), Expect = 5e-59
Identities = 223/869 (25%), Positives = 301/869 (34%), Gaps = 156/869 (17%)
Query: 161 DVDECRTHNGGCQHR--CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALG--NGGCQHH 216
DVDEC C C NTP SY C CKPG++ + + C I+ C NGGC H
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDYYNGGCVHE 90
Query: 217 CVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQL 276
C+ + +RC C GF L DG +C+ C + NG C C G C+CH G+ L
Sbjct: 91 CINIP-GNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFL 149
Query: 277 AADGKAC----EDVDECAAGLAQCAHGCLNT-QGSFKCVCHAGYELGADGRQCYRIEMEI 331
+ + C + C CAH C T +G C C G++L + + C
Sbjct: 150 SDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC------- 202
Query: 332 VNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQVCTNNP 390
+C NGGC H C T GP C C + Y L +D RTCI+ CA ++ C + C +
Sbjct: 203 TLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIET--CAVNNGGCDRTCKDTA 260
Query: 391 GGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRG 450
G C C G+ L DG C+D++EC + GGC+H C N GSF+C C GY+L D R
Sbjct: 261 TGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERT 320
Query: 451 CSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFV 510
C ++ E F R HI + P FQ + L
Sbjct: 321 CQDID--------ECSFERTCDHICI---NSPGSFQ----------CLCHRGYILYGTTH 359
Query: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEG----WTGLICNETCPPDTFGKNC-S 565
C D +CS++ C G G C CP G W G C ET + K
Sbjct: 360 CGDVD---ECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPR 416
Query: 566 FSCSCQNGGTCDSVTGACRC-----PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCH 620
SC G +S +C P + G P G GK +K+ ++
Sbjct: 417 AQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVP-GPQGKALQKRNGTSS----- 470
Query: 621 RLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE 680
GP CS+ RD C +
Sbjct: 471 ------------------------GLGPSCSDAPTTPIKQKARFKIRDAKCHLR-----P 501
Query: 681 RCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNC 740
QA + P V + CDS R + E + T
Sbjct: 502 HSQARAKETARQPLLDHCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEEA 561
Query: 741 SSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEI--------CPACQHA 792
S +C + C R + +A R +G Q+ Q
Sbjct: 562 SDTC------------EADCLRKRAEQSLQAAIKTLRKSIGRQQFYVQVSGTEYEVAQRP 609
Query: 793 ARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWT 852
A+ GAC S+C P +G SC G G SC P
Sbjct: 610 AKALEGQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCM-PGTYQDMEGQLSCTP--- 665
Query: 853 GFSCQRACDTGHWGPDCSHPC--NCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG 910
C + G G C CS G S D G C+A CP G +
Sbjct: 666 ---CPSSDGLGLPGARNVSECGGQCSPGFFSAD---GFKPCQA----------CPVGTYQ 709
Query: 911 PGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDA 970
P G C G +H F DC + +C+ G +
Sbjct: 710 P----------------EPGRTGCFPCGGGLLTKHEGTTSF--QDCEAKVHCSPGHHYNT 751
Query: 971 VNGSCL-CPAGRRGPRCAE----TCPAHT 994
C+ CP G P + TCP +T
Sbjct: 752 TTHRCIRCPVGTYQPEFGQNHCITCPGNT 780
Score = 97.8 bits (242), Expect = 7e-20
Identities = 121/459 (26%), Positives = 162/459 (35%), Gaps = 93/459 (20%)
Query: 782 CQEICPACQHAARCD--PETGACLCLPGFVGS--RCQDV--CPAGWYGPSCQTRCSCAND 835
C E C A C P++ CLC PG+ G +C+D+ C +Y C C
Sbjct: 37 CSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINI-- 94
Query: 836 GHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI------SGLC 889
P C+C G+ H G +C C +G C I S C
Sbjct: 95 ----PGNYRCTCFDGFM---------LAHDGHNCLDVDECQDNNGGCQQICVNAMGSYEC 141
Query: 890 LCEAGYVGPRCEQQC-PQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACP 948
C +G+ + C + + G C + HG C H+ P G G C+ C
Sbjct: 142 QCHSGFFLSDNQHTCIHRSNEGMNCMNK---DHG--CAHI--CRETPKG--GVACD--CR 190
Query: 949 AGFFGLDCRSACNCTAGAACDAVNGSC--LCPAGRRGPRCA--ETCPAHTYGHNCSQACA 1004
GF + C T C+ NG C C GP C + H+ G C + CA
Sbjct: 191 PGFDLAQNQKDCTLT----CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCA 246
Query: 1005 CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLY----GDNCR--HSCLCQNGGTCDPV- 1057
NG CD C G C +CP G G C+ + CL NGG CD
Sbjct: 247 VNNG-GCDRT-----CKDTATGVRC--SCPVGFTLQPDGKTCKDINECLVNNGG-CDHFC 297
Query: 1058 -----SGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG 1112
S C C +G+ L E+ C D C C + + P + +CLC G+
Sbjct: 298 RNTVGSFECGCRKGYKLLTDERTCQDID---ECSFERTCDHICINSPGSFQCLCHRGYI- 353
Query: 1113 DKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGS----FG 1168
G E SC G C + G+ C CPPG G
Sbjct: 354 --LYGTTHCGDVDECSMSNGSCDQG--CVNTKGSYEC-----------VCPPGRRLHWNG 398
Query: 1169 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCP 1207
+DC + +C A +CS A G SC CP
Sbjct: 399 KDCVETGKCLSRAKTSPRAQLSCSKAGGVE--SCFLSCP 435
Score = 81.3 bits (199), Expect = 7e-15
Identities = 125/497 (25%), Positives = 163/497 (32%), Gaps = 115/497 (23%)
Query: 1044 HSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR 1103
H C+ GT G A G G EC + C C N P + +
Sbjct: 9 HLCVLLALGT----RGRLAGGSGLPGSVDVDEC--SEGTDDCHIDAICQN----TPKSYK 58
Query: 1104 CLCPAGWTGD--KCQS--PCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE 1159
CLC G+ G+ +C+ C ++ C C PG C C GF +
Sbjct: 59 CLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPG------NYRCTCFDGFMLA--- 109
Query: 1160 QACPPGSFGEDCAQMCQCPGENPACHP----ATGT--CSCAAGY----HGPSCQQRCPPG 1209
G +C + +C N C A G+ C C +G+ + +C R G
Sbjct: 110 ------HDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEG 163
Query: 1210 ----RYGPGCEQLCGCLNGGSCDAATGACRCPTGF----LGTDCNLTCPQGRFGPNCTHV 1261
GC +C G AC C GF DC LTC G G C H
Sbjct: 164 MNCMNKDHGCAHICRETPKGGV-----ACDCRPGFDLAQNQKDCTLTCNYGNGG--CQHS 216
Query: 1262 CGCGQGAACDPVTG-TCLCPPGRA----GVRCERGCPQNRFGVGCEHTCSCRNGGLCHAS 1316
C D TG TC C A G C C N G C+ TC G+
Sbjct: 217 CE-------DTDTGPTCGCHQKYALHSDGRTCIETCAVNNGG--CDRTCKDTATGV---- 263
Query: 1317 NGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNST---CEPATGTCRCGPGFYGQA 1373
CSC +G+T + P G+ + EC +N C G+ CG
Sbjct: 264 --RCSCPVGFTLQ------PDGKTCKDIN-ECLVNNGGCDHFCRNTVGSFECG------- 307
Query: 1374 CEHPCPPGFH----GAGCQGLCWCQHGAPCD------PISGRCLCPAGFHGHFCERGCEP 1423
C G+ CQ + C CD P S +CLC G+
Sbjct: 308 ----CRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLC---HRGYILYGTTHC 360
Query: 1424 GSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDC-------RRGQFGPSCTLH 1476
G E CD G + C+CPPGR DC R + P L
Sbjct: 361 GDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLS 420
Query: 1477 CDCGGGADCDPVSGQCH 1493
C GG + +S H
Sbjct: 421 CSKAGGVESCFLSCPAH 437
Score = 79.0 bits (193), Expect = 3e-14
Identities = 113/440 (25%), Positives = 142/440 (32%), Gaps = 114/440 (25%)
Query: 1023 GWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVR 1082
G G + C G D+C +CQN P S C C G+ G K+C D
Sbjct: 27 GLPGSVDVDECSEGT--DDCHIDAICQN----TPKSYKCLCKPGYKGEG--KQCEDIDEC 78
Query: 1083 AGCRHSGGCLNGGLCDPHTGRCLCPAGWT----------GDKCQSPCLRGWFGEACAQRC 1132
++GGC++ + P RC C G+ D+CQ C Q C
Sbjct: 79 ENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDN------NGGCQQIC 132
Query: 1133 SCPPGAACHHVTGACRCPPGFTGSGCEQACPPGS------FGED--CAQMC-QCPGENPA 1183
G+ C+C GF S + C S +D CA +C + P A
Sbjct: 133 VNAMGSY------ECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVA 186
Query: 1184 CHPATG--------TCSCAAGYHGPSCQQRCPPGRYGP--GCEQ-------------LCG 1220
C G C+ Y CQ C GP GC Q C
Sbjct: 187 CDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCA 246
Query: 1221 CLNGG---SC-DAATGA-CRCPTGFLGTDCNLTCPQGRF----GPNCTHVC--------- 1262
NGG +C D ATG C CP GF TC C H C
Sbjct: 247 VNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFEC 306
Query: 1263 GCGQG-------------------AACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEH 1303
GC +G CD + C+ PG C RG +G
Sbjct: 307 GCRKGYKLLTDERTCQDIDECSFERTCDHI---CINSPGSFQCLCHRG--YILYG----- 356
Query: 1304 TCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGR----YGAACHLECSCHNNSTCEPA 1359
T C + C SNGSC G T E CPPGR G C C + + P
Sbjct: 357 TTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSP- 415
Query: 1360 TGTCRCGPGFYGQACEHPCP 1379
C ++C CP
Sbjct: 416 RAQLSCSKAGGVESCFLSCP 435
Score = 68.6 bits (166), Expect = 5e-11
Identities = 42/101 (41%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 110 CCRGWMQQPDEEGCLSA-ECSAS-LCFHGGRCVPGSAQPCHCPPGF--QGPRCQYDVDEC 165
C +G+ DE C ECS C H PGS Q C C G+ G DVDEC
Sbjct: 308 CRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQ-CLCHRGYILYGTTHCGDVDEC 366
Query: 166 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSC 206
NG C CVNT GSY C C PG RLH + + C+ C
Sbjct: 367 SMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKC 407
Score = 66.2 bits (160), Expect = 2e-10
Identities = 113/496 (22%), Positives = 157/496 (31%), Gaps = 117/496 (23%)
Query: 409 GCEDVDECASSRGGC--EHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELP 466
G DVDEC+ C + C N S++C C+ GY+ + + C ++E D
Sbjct: 30 GSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECENDY----- 82
Query: 467 FVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLT--EKFVCLDDSFGHDCSLTC 524
+ G E + G + T + F+ D GH+C L
Sbjct: 83 ---------------------YNGGCVHECINIPGNYRCTCFDGFMLAHD--GHNC-LDV 118
Query: 525 DDCR-NGGTC------LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCD 577
D+C+ N G C +G C C G+ TC N +C ++ G C
Sbjct: 119 DECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC---IHRSNEGMNCMNKDHG-CA 174
Query: 578 SVTGACR-CPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRF 636
+ CR P G +C G K C CN N G
Sbjct: 175 HI---CRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGG------------------- 212
Query: 637 CHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCW 696
C +C GP C C Q + D R +C G C C+ G
Sbjct: 213 CQHSCEDTDTGPTCG----CHQKYALHSDGRTCIETCAVNNGG--CDRTCKDTATG---- 262
Query: 697 QACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG 756
C+CPVG P G +D EC V G + + G C G
Sbjct: 263 VRCSCPVGFTLQ----------PDGKTCKDI-NECLVNNGGCDHFCRNTVGSFECGCRKG 311
Query: 757 QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFV---GSRC 813
RT +D + +C R C H P + CLC G++ + C
Sbjct: 312 YKLLTDERTCQDID-ECSFER----------TCDHICINSPGSFQCLCHRGYILYGTTHC 360
Query: 814 QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPG----WTGFSC---QRACDTGHWG 866
DV SC C + C C PG W G C +
Sbjct: 361 GDVDECSMSNGSCDQGCVNTKGSY------ECVCPPGRRLHWNGKDCVETGKCLSRAKTS 414
Query: 867 PDCSHPCNCSAGHGSC 882
P C+ + G SC
Sbjct: 415 PRAQLSCSKAGGVESC 430
Score = 38.9 bits (89), Expect = 0.039
Identities = 50/173 (28%), Positives = 59/173 (34%), Gaps = 34/173 (19%)
Query: 1102 GRCLCPAGWT--GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPP-------G 1152
G+ C AG KC + FG Q SC PG + G C P G
Sbjct: 615 GQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTY-QDMEGQLSCTPCPSSDGLG 673
Query: 1153 FTG----SGCEQACPPGSFGEDCAQMCQ-CPGENPACHPA-TGTCSCAAG----YHGPSC 1202
G S C C PG F D + CQ CP P TG C G + G +
Sbjct: 674 LPGARNVSECGGQCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTS 733
Query: 1203 QQRCPPGRYGPGCEQLCGCLNGGSCDAATGAC-RCPTGF----LGTDCNLTCP 1250
Q CE C G + T C RCP G G + +TCP
Sbjct: 734 FQ---------DCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCITCP 777
Score = 35.4 bits (80), Expect = 0.43
Identities = 47/196 (23%), Positives = 64/196 (32%), Gaps = 26/196 (13%)
Query: 1318 GSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGP-------GFY 1370
G+C G C +AC PG + +C T + G C P G
Sbjct: 617 GACGAGQVLQDSKC-VACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLGLP 675
Query: 1371 G----QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLC-PAGFHGHFCERGCEPGS 1425
G C C PGF A C P GR C P G G + S
Sbjct: 676 GARNVSECGGQCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCG--GGLLTKHEGTTS 733
Query: 1426 FGEGCHQRCDCDGGAPCDPVTGLCL-CPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1484
F + C + C G + T C+ CP G + +FG + + C D
Sbjct: 734 F-QDCEAKVHCSPGHHYNTTTHRCIRCPVGTY---------QPEFGQNHCITCPGNTSTD 783
Query: 1485 CDPVSGQCHCVDGYMG 1500
D + HC + + G
Sbjct: 784 FDGSTNVTHCKNQHCG 799
Score = 35.4 bits (80), Expect = 0.43
Identities = 38/148 (25%), Positives = 48/148 (32%), Gaps = 16/148 (10%)
Query: 1287 RCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSC-------GLGWTGRH----CELAC 1335
+C P FG SC G G SC GLG G C C
Sbjct: 629 KCVACGPGTHFGGELGQCVSCMPGTY-QDMEGQLSCTPCPSSDGLGLPGARNVSECGGQC 687
Query: 1336 PPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQH 1395
PG + A C T +P G C P G +H F C+ C
Sbjct: 688 SPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQ--DCEAKVHCSP 745
Query: 1396 GAPCDPISGRCL-CPAG-FHGHFCERGC 1421
G + + RC+ CP G + F + C
Sbjct: 746 GHHYNTTTHRCIRCPVGTYQPEFGQNHC 773
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 247 bits (630), Expect = 7e-65
Identities = 259/915 (28%), Positives = 322/915 (35%), Gaps = 233/915 (25%)
Query: 598 CPKGYYGKHCRKKCNCANRGRCHRL---YGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 654
C + YY C K C N H YG C G G+ C C + C
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAV--------CKQGC 249
Query: 655 Q-----CVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGC--------WQACTC 701
C P G C C G++G C EC + Y PGC WQ C C
Sbjct: 250 NLLHGGCTVP---------GECRCSYGWQGRFCD-EC-VPY--PGCVHGSCVEPWQ-CNC 295
Query: 702 PV---GVACDSVSGECGKRCPAGFQGEDCGQE-------CPVGTFGVNC--------SSS 743
G+ CD CG P G E CP G G NC S+
Sbjct: 296 ETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNP 355
Query: 744 CSCGGAPCHGVTG--QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA 801
C+ GG+ CH V +C CP G +G C D E +P
Sbjct: 356 CANGGS-CHEVPSGFECHCPSGWSGPTCALDIDE-----------------CASNPCAAG 397
Query: 802 CLCLPGFVGSRCQDVCPAGWYGPSCQTRCS------CANDGHCHPATG--HCSCAPGWTG 853
C+ G C +CP W G +CQ + C N C G +C C PGW G
Sbjct: 398 GTCVDQVDGFEC--ICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKG 455
Query: 854 FSCQRACDTGHWGPDCSHPCNCSAGHGSC-DAISGL-CLCEAGYVGPRCEQQCPQGHFGP 911
+C + DC C G+C D ++G C+C G+ G CE + + P
Sbjct: 456 INCHINVN------DCRGQCQHG---GTCKDLVNGYQCVCPRGFGGRHCELERDECASSP 506
Query: 912 GCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACD 969
C G C+ ++ C CP G+ G CE +D C GA C
Sbjct: 507 -------CHSGGLCEDLADGFHCHCPQGFSGPLCE-------VDVDLCEPSPCRNGARCY 552
Query: 970 AVNGS--CLCPAGRRGPRCA---ETCPAHTYGHNCSQACACFNGAS-----------CDP 1013
+ G C CP G C+ E CP G C C + A C P
Sbjct: 553 NLEGDYYCACPDDFGGKNCSVPREPCP----GGACRVIDGCGSDAGPGMPGTAASGVCGP 608
Query: 1014 VHGQCHCAPGWMGPSCLQACPAGLYGDNCRHS---CL---CQNGGTC-DPVSG-HCACPE 1065
HG+C PG SC+ C +G G C + CL C+NGGTC D V C CP
Sbjct: 609 -HGRCVSQPGG-NFSCI--CDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPS 664
Query: 1066 GWAGLACE---KECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRG 1122
GW G C+ +CLP C G C + + C C GW G C S
Sbjct: 665 GWEGELCDTNPNDCLPDP----CHSRGRCYD----LVNDFYCACDDGWKGKTCHS----- 711
Query: 1123 WFGEACAQRCSCPPGAACHHV--TGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGE 1180
E +C G C+ T C CPPG+ GS C A C C G
Sbjct: 712 --REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGS 769
Query: 1181 NPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG--ACRCPT 1238
A+ +C C G+ G +C C L C NGG C C C
Sbjct: 770 G-----ASFSCICRDGWEGRTCTHNT------NDCNPL-PCYNGGICVDGVNWFRCECAP 817
Query: 1239 GFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC-DPVTG-TCLCPPGRAGVRCE------- 1289
GF G DC + + + P C GA C D + G C CPPGRAG RC+
Sbjct: 818 GFAGPDCRINIDECQSSP-------CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGR 870
Query: 1290 ----RGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTG-RHCELACPPGRYGAAC 1344
RG P F G C + C +G C W G + C LA P A C
Sbjct: 871 SCWSRGTP---FPHGSSWVEDCNS---CRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQC 924
Query: 1345 HLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISG 1404
L C E A G C P CE W + GA +P S
Sbjct: 925 PLGQRC-----LEKAPGQCLRPP------CE---------------AWGECGAE-EPPST 957
Query: 1405 RCLCPAGFHGHFCER 1419
CL +G + C R
Sbjct: 958 PCLPRSGHLDNNCAR 972
Score = 221 bits (562), Expect = 6e-57
Identities = 224/757 (29%), Positives = 270/757 (35%), Gaps = 201/757 (26%)
Query: 860 CDTGHWGPDCSHPC---NCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR 916
CD ++ C+ C N GH +CD G C G++G C++ C+Q
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQY-GNKACMDGWMGKECKEAV--------CKQG 248
Query: 917 CQCQHGAACDHVSGACTCPAGWRGTFCEHACP-AGFFGLDCRS--ACNCT---AGAACD- 969
C HG V G C C GW+G FC+ P G C CNC G CD
Sbjct: 249 CNLLHGGCT--VPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDK 306
Query: 970 ----------AVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQ---ACA---CFNGASCDP 1013
NG A RC TCP G NC + AC C NG SC
Sbjct: 307 DLNYCGSHHPCTNGGTCINAEPDQYRC--TCPDGYSGRNCEKAEHACTSNPCANGGSCHE 364
Query: 1014 VHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC-DPVSG-HCACPEGWAG 1069
V +CHC GW GP+C L D C S C GGTC D V G C CPE W G
Sbjct: 365 VPSGFECHCPSGWSGPTC------ALDIDECA-SNPCAAGGTCVDQVDGFECICPEQWVG 417
Query: 1070 LACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQ---SPCLRGWF 1124
C+ + A CLN C G C C GW G C + C
Sbjct: 418 ATCQLD-------ANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDC----- 465
Query: 1125 GEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENP 1182
R C G C + C CP GF G CE ++CA +
Sbjct: 466 ------RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE------RDECA--------SS 505
Query: 1183 ACHPATGTC-SCAAGYHGPSCQQRCPPGRYGPGCE---QLC---GCLNGGSCDAATG--A 1233
CH + G C A G+H C CP G GP CE LC C NG C G
Sbjct: 506 PCH-SGGLCEDLADGFH---C--HCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 559
Query: 1234 CRCPTGFLGTDCNL---TCPQGRFGPNCTHVCGCGQGA-----------ACDPVTGTCLC 1279
C CP F G +C++ CP G C + GCG A C P G C+
Sbjct: 560 CACPDDFGGKNCSVPREPCPGGA----CRVIDGCGSDAGPGMPGTAASGVCGP-HGRCVS 614
Query: 1280 PPGRAGVRCERGCPQNRFGVGCEHTCS------CRNGGLC--HASNGSCSCGLGWTGRHC 1331
PG C C G C CRNGG C C C GW G C
Sbjct: 615 QPG-GNFSCI--CDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC 671
Query: 1332 E-------------------------LACPPGRYGAACH---LEC---SCHNNSTCEPAT 1360
+ AC G G CH +C +C N TC +
Sbjct: 672 DTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSG 731
Query: 1361 GTCRCGPGFYGQACEHPCPPGFHGAGC----QGLCW---CQHGAPC--DPISGRCLCPAG 1411
T RC CPPG+ G+ C C C +G C S C+C G
Sbjct: 732 DTFRCA-----------CPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDG 780
Query: 1412 FHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGL-CLCPPGRSGATCNLDCRRGQFG 1470
+ G C C+ +GG D V C C PG +G C ++ Q
Sbjct: 781 WEGRTCTHNT------NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSS 834
Query: 1471 PSCTLHCDCGGGADC-DPVSG-QCHCVDGYMGPTCRE 1505
P C GA C D ++G +C C G GP C+E
Sbjct: 835 P-------CAYGATCVDEINGYRCSCPPGRAGPRCQE 864
Score = 212 bits (539), Expect = 3e-54
Identities = 242/869 (27%), Positives = 307/869 (35%), Gaps = 216/869 (24%)
Query: 511 CLDDSFGHDCSLTCDDCRNGGTCLLG---LDG-CDCPEGWTGLICNETCP-PDTFGKNC- 564
C+D G +C C+ G L G + G C C GW G C+E P P +C
Sbjct: 231 CMDGWMGKECKEAV--CKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCV 288
Query: 565 -SFSCSCQ----------------------NGGTCDSVTG---ACRCPPGVSGTNCEDGC 598
+ C+C+ NGGTC + C CP G SG NCE
Sbjct: 289 EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK-- 346
Query: 599 PKGYYGKHCRKKCNCANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQC 656
+H CAN G CH + C C G G C L A P C+ C
Sbjct: 347 -----AEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNP-CAAGGTC 400
Query: 657 VQPHTQSCDKRDG-SCSCKAGFRGERCQA---ECELGYFGPGCWQACTCP---VGVACDS 709
V D+ DG C C + G CQ ECE G C A +C G CD
Sbjct: 401 V-------DQVDGFECICPEQWVGATCQLDANECE----GKPCLNAFSCKNLIGGYYCDC 449
Query: 710 VSGECGKRCPAGFQGEDCGQECPVG------TFGVNCSSSCSCGGAPCHGVTGQCRCPPG 763
+ G G C DC +C G G C GG C +C P
Sbjct: 450 IPGWKGINCHINV--NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPC 507
Query: 764 RTGEDCE-------ADCPEGRWGLGCQ---EIC--PACQHAARCDPETG--ACLCLPGFV 809
+G CE CP+G G C+ ++C C++ ARC G C C F
Sbjct: 508 HSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFG 567
Query: 810 GSRC---QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG 866
G C ++ CP G +C+ C +D PG G + C G
Sbjct: 568 GKNCSVPREPCPGG----ACRVIDGCGSD-----------AGPGMPGTAASGVC-----G 607
Query: 867 PDCSHPCNCSAGHGSCDAISG---LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGA 923
P HG C + G C+C++G+ G C + P C++G
Sbjct: 608 P-----------HGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQP-------CRNGG 649
Query: 924 AC-DHVSG-ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNG-SCLCPAG 980
C D V C CP+GW G C+ P C S C D VN C C G
Sbjct: 650 TCIDEVDAFRCFCPSGWEGELCD-TNPNDCLPDPCHSRGRC-----YDLVNDFYCACDDG 703
Query: 981 RRGPRCAE---TCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGL 1037
+G C C A+T CS C++ +C C PGW G +C A
Sbjct: 704 WKGKTCHSREFQCDAYT----CSNGGTCYDSGDT----FRCACPPGWKGSTCAVA----- 750
Query: 1038 YGDNCRHSCL---CQNGGTC--DPVSGHCACPEGWAGLAC---EKECLPRDVRAGCRHSG 1089
SCL C NGGTC S C C +GW G C +C P
Sbjct: 751 ----KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLP--------- 797
Query: 1090 GCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAAC-HHVTG- 1145
C NGG+C RC C G+ G C+ + C Q C GA C + G
Sbjct: 798 -CYNGGICVDGVNWFRCECAPGFAGPDCRINI------DEC-QSSPCAYGATCVDEINGY 849
Query: 1146 ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQR 1205
C CPPG G C++ FG C P H ++ C SC R
Sbjct: 850 RCSCPPGRAGPRCQEVI---GFGRSCWSR-----GTPFPHGSSWVEDC------NSC--R 893
Query: 1206 CPPGRYGPGCEQL-CG---CLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHV 1261
C GR C ++ CG CL G +A + C LG C P P C
Sbjct: 894 CLDGR--RDCSKVWCGWKPCLLAGQPEALSAQCP-----LGQRCLEKAPGQCLRPPCEAW 946
Query: 1262 CGCGQGAACDPVTGTCLCPPGRAGVRCER 1290
CG A +P + CL G C R
Sbjct: 947 GECG---AEEPPSTPCLPRSGHLDNNCAR 972
Score = 166 bits (420), Expect = 2e-40
Identities = 197/696 (28%), Positives = 262/696 (37%), Gaps = 148/696 (21%)
Query: 133 CFHGGRCVPGSAQP----CHCPPGFQGPRCQYDVDECRTH---NGGCQHRCVNTPGSYLC 185
C +GG C+ +A+P C CP G+ G C+ C ++ NGG C P + C
Sbjct: 317 CTNGGTCI--NAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG---SCHEVPSGFEC 371
Query: 186 ECKPGFRLHTDSRTC-LAINSCALGNGGCQHHCVQLTITRHRCQCRP---GFQLQEDGRH 241
C G+ TC L I+ CA CV + C C G Q D
Sbjct: 372 HCPSGW----SGPTCALDIDECASNPCAAGGTCVD-QVDGFECICPEQWVGATCQLDANE 426
Query: 242 CVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGLAQCAHG- 299
C PC N C+ + G C+C G++ G C +V++C QC HG
Sbjct: 427 C-EGKPCLN-----AFSCKNLIGGYYCDCIPGWK----GINCHINVNDCR---GQCQHGG 473
Query: 300 -CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCP 358
C + ++CVC G+ GR C +E + S ++GG C + G C CP
Sbjct: 474 TCKDLVNGYQCVCPRGF----GGRHC-ELERDECASSPCHSGGL---CEDLADGFHCHCP 525
Query: 359 RGYELDTDQRTCIDVDDCADSPCCQQV-CTNNPGGYECGC---YAGYRLS-----ADGCG 409
+G+ + +DVD C SPC C N G Y C C + G S G
Sbjct: 526 QGFSGPLCE---VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGA 582
Query: 410 CEDVDECASSRG------------GCEHHCTNL-AGSFQCSCEAGYR---LHEDRRGC-- 451
C +D C S G G C + G+F C C++G+ HE+ C
Sbjct: 583 CRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLG 642
Query: 452 SPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGE-HTLTEKFV 510
P +D F P + + EL +D + + RG + L F
Sbjct: 643 QPCRNGGTCIDEVDAFRCFCP--SGWEGELCDTNPNDCL---PDPCHSRGRCYDLVNDFY 697
Query: 511 C-LDDSFG----HDCSLTCD--DCRNGGTCLLGLD--GCDCPEGWTGLIC----NETCPP 557
C DD + H CD C NGGTC D C CP GW G C N +C P
Sbjct: 698 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLP 757
Query: 558 D-------TFGKNCSFSCSCQN---GGTCDSVTGACRCPPGVSGTNCEDG-------CPK 600
+ G SFSC C++ G TC T C P +G C DG C
Sbjct: 758 NPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAP 817
Query: 601 GYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC----QC 656
G+ G CR + C YGA C + G C +CPP GP C E C
Sbjct: 818 GFAGPDCRINIDECQSSPC--AYGA-TCVDEINGYRC--SCPPGRAGPRCQEVIGFGRSC 872
Query: 657 VQ-----PHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQAC-----------T 700
PH S + SC C G R +C + G W+ C
Sbjct: 873 WSRGTPFPHGSSWVEDCNSCRCLDGRR------DCSKVWCG---WKPCLLAGQPEALSAQ 923
Query: 701 CPVGVAC-DSVSGECGKRCPAGFQGEDCGQECPVGT 735
CP+G C + G+C R P GE CG E P T
Sbjct: 924 CPLGQRCLEKAPGQC-LRPPCEAWGE-CGAEEPPST 957
Score = 74.7 bits (182), Expect = 6e-13
Identities = 83/339 (24%), Positives = 117/339 (34%), Gaps = 88/339 (25%)
Query: 127 ECSASLCFHGGRCVPG-SAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLC 185
+C C +GG C+ A C CP G++G C + ++C + RC + + C
Sbjct: 639 DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 698
Query: 186 ECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRR 245
C G++ T ++ NGG C T RC C PG+ +
Sbjct: 699 ACDDGWKGKTCHSREFQCDAYTCSNGGT---CYDSGDT-FRCACPPGW----------KG 744
Query: 246 SPCA-NRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG--CLN 302
S CA +N SC+ C +G C+
Sbjct: 745 STCAVAKNSSCLPN------------------------------------PCVNGGTCVG 768
Query: 303 TQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA----NNGGCSHGCSHTSAGPLCTCP 358
+ SF C+C G+E GR C N C N G C G + C C
Sbjct: 769 SGASFSCICRDGWE----GRTC----THNTNDCNPLPCYNGGICVDGVNWFR----CECA 816
Query: 359 RGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECGCYAGYRLSADGCGCEDV---- 413
G+ D R I++D+C SPC C + GY C C G G C++V
Sbjct: 817 PGF-AGPDCR--INIDECQSSPCAYGATCVDEINGYRCSCPPG----RAGPRCQEVIGFG 869
Query: 414 DECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCS 452
C S H + + C C G RR CS
Sbjct: 870 RSCWSRGTPFPHGSSWVEDCNSCRCLDG------RRDCS 902
Score = 59.7 bits (143), Expect = 2e-08
Identities = 63/212 (29%), Positives = 91/212 (42%), Gaps = 27/212 (12%)
Query: 125 SAECSASLCFHGGRCV-PGSAQPCHCPPGFQGPRCQYDVDECR---THNGGCQHRCVNTP 180
++ C + C +GG CV G++ C C G++G C ++ ++C +NGG CV+
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI---CVDGV 808
Query: 181 GSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF---QLQE 237
+ CEC PGF D R + I+ C CV I +RC C PG + QE
Sbjct: 809 NWFRCECAPGF-AGPDCR--INIDECQSSPCAYGATCVD-EINGYRCSCPPGRAGPRCQE 864
Query: 238 ---DGRHCVRRSPCANRNGSCMHRCQVVRGL-ARCECHVGYQLAADGKACEDVDECAAGL 293
GR C R S + C R L R +C ++ K C + A
Sbjct: 865 VIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCS---KVWCGWKPCLLAGQPEALS 921
Query: 294 AQCAHG--CLNTQGSFKCV---CHAGYELGAD 320
AQC G CL + +C+ C A E GA+
Sbjct: 922 AQCPLGQRCLE-KAPGQCLRPPCEAWGECGAE 952
Score = 58.9 bits (141), Expect = 4e-08
Identities = 54/200 (27%), Positives = 70/200 (35%), Gaps = 37/200 (18%)
Query: 1335 CPPGRYGAACHLECSCHNNS----TCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGL 1390
C Y A C+ C N+ TC+ G C G+ G+ C+ A C+
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQY-GNKACMDGWMGKECKE--------AVCKQG 248
Query: 1391 CWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCL 1450
C HG P G C C G+ G FC+ C C G+ +P C
Sbjct: 249 CNLLHGGCTVP--GECRCSYGWQGRFCDE----------CVPYPGCVHGSCVEPWQ--CN 294
Query: 1451 CPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADC---DPVSGQCHCVDGYMGPTCREGG 1507
C G C+ D C H C G C +P +C C DGY G C E
Sbjct: 295 CETNWGGLLCDKDLNY------CGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC-EKA 347
Query: 1508 PLRLPENPSLAQGSAGTLPA 1527
NP GS +P+
Sbjct: 348 EHACTSNPCANGGSCHEVPS 367
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 244 bits (622), Expect = 6e-64
Identities = 126/329 (38%), Positives = 167/329 (50%), Gaps = 21/329 (6%)
Query: 133 CFHGGRCVPGSAQPCHCPPGFQ----GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECK 188
C H +PG+ + C C GF G C DVDEC NGGCQ CVN GSY C C+
Sbjct: 82 CVHDCVNIPGNYR-CTCYDGFHLAHDGHNC-LDVDECAEGNGGCQQSCVNMMGSYECHCR 139
Query: 189 PGFRLHTDSRTCLAIN----SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVR 244
GF L + TC+ +C N GC H C + C+CRPGF+L ++ R C
Sbjct: 140 EGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDC-- 197
Query: 245 RSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQ 304
+ C NG C H C RC CH+ + L DGK C ++ CA C C +
Sbjct: 198 KLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGCDSKCHDAA 255
Query: 305 GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELD 364
C C G+ L D + C I+ C NNGGC H C +T C+C +GY+L
Sbjct: 256 TGVHCTCPVGFMLQPDRKTCKDID-----ECRLNNGGCDHICRNTVGSFECSCKKGYKLL 310
Query: 365 TDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCE 424
++R C D+D+C+ C +C N PG ++C C+ GY L C DVDEC+ +RGGC
Sbjct: 311 INERNCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCR 369
Query: 425 HHCTNLAGSFQCSCEAGY-RLHEDRRGCS 452
C N GS+QC+C AG RLH + + C+
Sbjct: 370 FGCINTPGSYQCTCPAGQGRLHWNGKDCT 398
Score = 224 bits (571), Expect = 5e-58
Identities = 223/828 (26%), Positives = 288/828 (34%), Gaps = 142/828 (17%)
Query: 154 QGPRCQYDVDECRTHNGGCQHR--CVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL-GN 210
Q + DVDEC C C NTP SY C CK G+ D + C ++ C N
Sbjct: 22 QYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDN 79
Query: 211 GGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCEC 270
GC H CV + +RC C GF L DG +C+ CA NG C C + G C C
Sbjct: 80 AGCVHDCVNIP-GNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHC 138
Query: 271 HVGYQLAADGKAC----EDVDECAAGLAQCAHGCLNT-QGSFKCVCHAGYELGADGRQCY 325
G+ L+ + C E+ C CAH C T +G C C G+EL + R C
Sbjct: 139 REGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCK 198
Query: 326 RIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQ 384
+C NGGC H C T GP C C + L TD +TCI+ CA ++ C
Sbjct: 199 L-------TCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGCDS 249
Query: 385 VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRL 444
C + G C C G+ L D C+D+DEC + GGC+H C N GSF+CSC+ GY+L
Sbjct: 250 KCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKL 309
Query: 445 HEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHT 504
+ R C ++ E F R HI V P FQ +
Sbjct: 310 LINERNCQDID--------ECSFDRTCDHICV---NTPGSFQ----------CLCHRGYL 348
Query: 505 LTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEG-----WTG----------- 548
L C D +CS+ CR G G C CP G W G
Sbjct: 349 LYGITHCGDVD---ECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQG 405
Query: 549 --------LICNETCPPDTFGKNC----SFSCSCQNGGTCDSVTGACRCPPGVSGTNCED 596
L CN + DT C F +NG T T + R P +G N
Sbjct: 406 SPGASKAMLSCNRSGKKDTCALTCPSRARFLPESENGFTVSCGTPSPRAAPARAGHN--- 462
Query: 597 GCPKGYYGKHCRKKCNCANRGRCHRLYGACLC-----DPGLYGRFCHLTCPPWAFGPGCS 651
HC + + + R C + G +T P G CS
Sbjct: 463 --GNSTNSNHCHEAAVLSIKQRASFKIKDAKCRLHLRNKGKTEEAGRITGPG---GAPCS 517
Query: 652 EECQCVQPHTQSCDKRDG----------------SCSCKAGFRGERCQAECELGYFGPGC 695
ECQ H + R G + +A R E A C L
Sbjct: 518 -ECQVTFIHLKCDSSRKGKGRRARTPPGKEVTRLTLELEAEVRAEETTASCGLPCLRQRM 576
Query: 696 WQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVT 755
+ + + S++ + AG E + V SC G
Sbjct: 577 ERRLKGSLKMLRKSINQDRFLLRLAGLDYELAHKPGLVAGERAEPMESCRPG-------- 628
Query: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPAC--------QHAARCD--PETGACLCL 805
R G C CP+G + G E C C + CD P + A L
Sbjct: 629 ------QHRAGTKC-VSCPQGTYYHGQTEQCVPCPAGTFQEREGQLSCDLCPGSDAHGPL 681
Query: 806 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHW 865
+ C CP G + C G P G C F C T H
Sbjct: 682 GATNVTTCAGQCPPGQHSVDGFKPCQPCPRGTYQPEAGRTLC------FPCGGGLTTKHE 735
Query: 866 G----PDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQ----QCP 905
G DC CS GH +I C G P Q +CP
Sbjct: 736 GAISFQDCDTKVQCSPGHYYNTSIHRCIRCAMGSYQPDFRQNFCSRCP 783
Score = 138 bits (347), Expect = 5e-32
Identities = 136/496 (27%), Positives = 189/496 (38%), Gaps = 96/496 (19%)
Query: 262 VRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG--CLNTQGSFKCVCHAGYELGA 319
V GL V + A KA +DVDEC G C C NT S+KC+C +GY
Sbjct: 6 VPGLCLLVLLVHARAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--G 63
Query: 320 DGRQCYRIEMEIVNSCE-ANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD 378
DG+ C + V+ CE +N GC H C + CTC G+ L D C+DVD+CA+
Sbjct: 64 DGKHC-----KDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAE 118
Query: 379 -SPCCQQVCTNNPGGYECGCYAGYRLSADGCGC----EDVDECASSRGGCEHHCTNL-AG 432
+ CQQ C N G YEC C G+ LS + C E+ C + GC H C G
Sbjct: 119 GNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKG 178
Query: 433 SFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQD---DD 489
C C G+ L +++R C +L + +
Sbjct: 179 GIACECRPGFELTKNQRDC----------------------------KLTCNYGNGGCQH 210
Query: 490 VGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCD--CPEGWT 547
D E+ G H KFV H TC + TC + GCD C + T
Sbjct: 211 TCDDTEQGPRCGCHI---KFVL------HTDGKTCIE-----TCAVNNGGCDSKCHDAAT 256
Query: 548 GLICNETCP------PDTFGKNCSFSCSCQ-NGGTCDSVTGACRCPPGVSGTNCEDGCPK 600
G+ C TCP PD K C C+ N G CD + CR G +C+ G
Sbjct: 257 GVHC--TCPVGFMLQPDR--KTCKDIDECRLNNGGCDHI---CRNTVGSFECSCKKGYKL 309
Query: 601 GYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP-GCSEECQCVQP 659
++C+ C+ C + C+ PG + CH + G +EC +
Sbjct: 310 LINERNCQDIDECSFDRTCDHI---CVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRG 366
Query: 660 HTQ-SCDKRDGS--CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGK 716
+ C GS C+C AG + L + G C + C C +
Sbjct: 367 GCRFGCINTPGSYQCTCPAG--------QGRLHWNGKDCTEPLKCQGSPGASKAMLSCNR 418
Query: 717 RCPAGFQGEDCGQECP 732
+ + C CP
Sbjct: 419 ----SGKKDTCALTCP 430
Score = 90.9 bits (224), Expect = 9e-18
Identities = 203/847 (23%), Positives = 258/847 (30%), Gaps = 210/847 (24%)
Query: 667 RDGSCSCKAGFRGE--RCQ--AECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGF 722
R C CK+G+ G+ C+ ECE GC C ++ G C GF
Sbjct: 51 RSYKCICKSGYTGDGKHCKDVDECE-REDNAGCVHDCV--------NIPGNYRCTCYDGF 101
Query: 723 ----QGEDC--GQECPVGTFGVNCSSSC--SCGGAPCHGVTGQCRCPPGRTGEDCEADC- 773
G +C EC G G C SC G CH C G D + C
Sbjct: 102 HLAHDGHNCLDVDECAEGNGG--CQQSCVNMMGSYECH-------CREGFFLSDNQHTCI 152
Query: 774 --PEGRWGLGCQEICPACQHAARCDPETG-ACLCLPGFVGSR---------------CQD 815
PE G+ C C H R P+ G AC C PGF ++ CQ
Sbjct: 153 QRPEE--GMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH 210
Query: 816 VCPAGWYGP---------------SCQTRCSCAN---DGHCH-PATG-HCSCAPGWTGFS 855
C GP +C C+ N D CH ATG HC+C GF
Sbjct: 211 TCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCP---VGFM 267
Query: 856 CQRACDTGHWGPDCSHPCNCSAGHGSCDAI------SGLCLCEAGYVGPRCEQQCPQGHF 909
Q T C C +G CD I S C C+ GY E+
Sbjct: 268 LQPDRKT------CKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINER------- 314
Query: 910 GPGCEQRCQCQHGAACDHV------SGACTCPAG---WRGTFCEHACPAGFFGLDCRSAC 960
C+ +C CDH+ S C C G + T C CR C
Sbjct: 315 --NCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGC 372
Query: 961 NCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFN--GASCDPVHGQC 1018
T G+ C CPAG+ H G +C++ C GAS
Sbjct: 373 INTPGSY------QCTCPAGQG--------RLHWNGKDCTEPLKCQGSPGAS----KAML 414
Query: 1019 HCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLP 1078
C +C CP+ R +NG T C P P
Sbjct: 415 SCNRSGKKDTCALTCPS-----RARFLPESENGFTVS-----CGTPS------------P 452
Query: 1079 RDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQ-SPC---LRGWFGEACAQRCSC 1134
R A H+G N C H L K + + C LR A R +
Sbjct: 453 RAAPARAGHNGNSTNSNHC--HEAAVLSIKQRASFKIKDAKCRLHLRNKGKTEEAGRITG 510
Query: 1135 PPGAACHHVTGA---CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC 1191
P GA C +C G G PP G++ ++ T +C
Sbjct: 511 PGGAPCSECQVTFIHLKCDSSRKGKGRRARTPP---GKEVTRLTLELEAEVRAEETTASC 567
Query: 1192 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ 1251
G C ++ R + L +N R G D L
Sbjct: 568 -------GLPCLRQRMERRLKGSLKMLRKSINQD---------RFLLRLAGLDYEL---- 607
Query: 1252 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPG--RAGVRCERGCPQNRFGVGCEHTCSCRN 1309
H G G +P+ C PG RAG +C CPQ + G C
Sbjct: 608 -------AHKPGLVAGERAEPMES---CRPGQHRAGTKCV-SCPQGTYYHGQTEQCVPCP 656
Query: 1310 GGLCHASNGSCSCG----------LGWTG-RHCELACPPGRYGAACHLECSCHNNSTCEP 1358
G G SC LG T C CPPG++ C T +P
Sbjct: 657 AGTFQEREGQLSCDLCPGSDAHGPLGATNVTTCAGQCPPGQHSVDGFKPCQPCPRGTYQP 716
Query: 1359 ATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCL-CPAG-----F 1412
G C P G +H F C C G + RC+ C G F
Sbjct: 717 EAGRTLCFPCGGGLTTKHEGAISFQ--DCDTKVQCSPGHYYNTSIHRCIRCAMGSYQPDF 774
Query: 1413 HGHFCER 1419
+FC R
Sbjct: 775 RQNFCSR 781
Score = 82.0 bits (201), Expect = 4e-15
Identities = 109/426 (25%), Positives = 142/426 (33%), Gaps = 116/426 (27%)
Query: 782 CQEICPACQHAARCD--PETGACLCLPGFVGS--RCQDVCPAGWYGPSCQTRCSCANDGH 837
C E C A C P + C+C G+ G C+DV + C +D
Sbjct: 33 CVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDEC-----EREDNAGCVHDCV 87
Query: 838 CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI------SGLCLC 891
P C+C G+ H G +C C+ G+G C S C C
Sbjct: 88 NIPGNYRCTCYDGF---------HLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHC 138
Query: 892 EAGYVGPRCEQQCPQG-HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAG 950
G+ + C Q G C + HG C H+ P G G CE C G
Sbjct: 139 REGFFLSDNQHTCIQRPEEGMNCMNK---NHG--CAHICRET--PKG--GIACE--CRPG 187
Query: 951 FFGLDCRSACNCTAGAACDAVNGSC--LCPAGRRGPRCAETCP--AHTYGHNCSQACACF 1006
F + C T C+ NG C C +GPRC HT G C + CA
Sbjct: 188 FELTKNQRDCKLT----CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVN 243
Query: 1007 NGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL----CQ-NGGTCDPV---- 1057
NG CD +CH A G C CP G R +C C+ N G CD +
Sbjct: 244 NGG-CD---SKCHDAA--TGVHC--TCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNT 295
Query: 1058 --SGHCACPEGWAGLACEKEC------------------LPRDVRAGCRHS--------- 1088
S C+C +G+ L E+ C P + C
Sbjct: 296 VGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITHC 355
Query: 1089 ----------GGCLNGGLCDPHTGRCLCPAG-----WTGDKCQSPCLRGWFGEACAQRCS 1133
GGC G + P + +C CPAG W G C P +C
Sbjct: 356 GDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPL-----------KCQ 404
Query: 1134 CPPGAA 1139
PGA+
Sbjct: 405 GSPGAS 410
Score = 73.6 bits (179), Expect = 1e-12
Identities = 113/462 (24%), Positives = 152/462 (32%), Gaps = 98/462 (21%)
Query: 1133 SCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGE-NPACH---- 1185
+C A C + + C C G+TG G + C + +C E N C
Sbjct: 39 NCHIDAICQNTPRSYKCICKSGYTGDG-----------KHCKDVDECEREDNAGCVHDCV 87
Query: 1186 --PATGTCSCAAGYH----GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTG 1239
P C+C G+H G +C GC+Q C + G C C G
Sbjct: 88 NIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSY------ECHCREG 141
Query: 1240 FLGTDCNLTCPQG-RFGPNCTHVC-GCGQGAACDPVTG-TCLCPPGRAGVRCERGCPQNR 1296
F +D TC Q G NC + GC P G C C PG + +R C
Sbjct: 142 FFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDC---- 197
Query: 1297 FGVGCEHTCSCRNGGLCHASNGS-----CSCGLGWT----GRHCELACPPGRYG--AACH 1345
+ TC+ NGG H + + C C + + G+ C C G + CH
Sbjct: 198 -----KLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCH 252
Query: 1346 -----LECSCHNNSTCEPATGT------CRCGPGFYGQAC-------EHPCPPGF----H 1383
+ C+C +P T CR G C E C G+ +
Sbjct: 253 DAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLIN 312
Query: 1384 GAGCQGLCWCQHGAPCD------PISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCD 1437
CQ + C CD P S +CLC G+ G E R C
Sbjct: 313 ERNCQDIDECSFDRTCDHICVNTPGSFQCLC---HRGYLLYGITHCGDVDECSINRGGCR 369
Query: 1438 GGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDG 1497
G P + C CP G+ N G CT C G C
Sbjct: 370 FGCINTPGSYQCTCPAGQGRLHWN--------GKDCTEPLKCQGSPGAS--KAMLSCNRS 419
Query: 1498 YMGPTCREGGPLR---LPENPSLAQGSAGTLPASSRPTSRSG 1536
TC P R LPE+ + S GT P+ +R+G
Sbjct: 420 GKKDTCALTCPSRARFLPESENGFTVSCGT-PSPRAAPARAG 460
Score = 62.0 bits (149), Expect = 4e-09
Identities = 127/526 (24%), Positives = 167/526 (31%), Gaps = 149/526 (28%)
Query: 885 ISGLCLCEAGYVGPRCEQQCPQGHFGPGC-EQRCQCQHGAACDHV--SGACTCPAGWRGT 941
+ GLCL V R Q C E C A C + S C C +G+ G
Sbjct: 6 VPGLCLLVL-LVHARAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD 64
Query: 942 FCEHACPAGFFGLDCRSACNC----TAGAACDAVN--GSCLCPAGRRGPRCAETCPAHTY 995
G C+ C AG D VN G+ C C +
Sbjct: 65 -----------GKHCKDVDECEREDNAGCVHDCVNIPGNYRCT-------CYDGFHLAHD 106
Query: 996 GHNCSQACACFNG-----ASCDPVHG--QCHCAPGWM----GPSCLQACPAGLYGDNCRH 1044
GHNC C G SC + G +CHC G+ +C+Q G+ N H
Sbjct: 107 GHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNH 166
Query: 1045 SC--LCQNGGTCDPVSGHCACPEGWAGLACEKECLP--------RDVRAGCRH-SGGCLN 1093
C +C+ P+G G+ACE C P RD + C + +GGC +
Sbjct: 167 GCAHICRE------------TPKG--GIACE--CRPGFELTKNQRDCKLTCNYGNGGCQH 210
Query: 1094 GGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGF 1153
CD D Q P RC C H C
Sbjct: 211 --TCD--------------DTEQGP------------RCGCHIKFVLHTDGKTCIETCAV 242
Query: 1154 TGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGP 1213
GC+ C + G C+C G+ P R
Sbjct: 243 NNGGCDSKCHDAATGVH--------------------CTCPVGF-------MLQPDR--K 273
Query: 1214 GCEQLCGC-LNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDP 1272
C+ + C LN G CD CR G C NC + C CD
Sbjct: 274 TCKDIDECRLNNGGCD---HICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDH 330
Query: 1273 VTGTCLCPPGRAGVRCERGCPQNRFGV---GCEHTCSCRNGGL---CHASNGS--CSCGL 1324
+ C+ PG C RG +G+ G CS GG C + GS C+C
Sbjct: 331 I---CVNTPGSFQCLCHRG--YLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPA 385
Query: 1325 G-----WTGRHC--ELACPPGRYGAACHLECSCHNNSTCEPATGTC 1363
G W G+ C L C G GA+ + SC+ + + TC
Sbjct: 386 GQGRLHWNGKDCTEPLKC-QGSPGASKAM-LSCNRSGKKDTCALTC 429
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 233 bits (594), Expect = 1e-60
Identities = 252/922 (27%), Positives = 334/922 (36%), Gaps = 160/922 (17%)
Query: 120 EEGCLSAECSASLCFHG-GRCVPG-SAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQ 173
E G S C + G GRC+ S C C GF QG RC DVDECR C
Sbjct: 474 ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA 532
Query: 174 H-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232
RC N+PGS+ C C PGFR + CL ++ C C + T C C G
Sbjct: 533 PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAG 592
Query: 233 FQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACE-DVDECA 290
+Q G C C G C C+ + G RC C G++ G ACE DVDECA
Sbjct: 593 YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECA 648
Query: 291 AGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSH 348
C G C NT GSF C C AG+ G C + V+ C + C++G C +
Sbjct: 649 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC-----QDVDECARSPPPCTYGRCEN 703
Query: 349 TSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECG-CYAGYRLSAD 406
T C CP G++ +T C DVD+C + C Q C N+PG ++C C +G+ L
Sbjct: 704 TEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 763
Query: 407 GCGCEDVDECASSRGGC--EHHCTNLAGSFQCSCEAGYRLHEDRRG-CSPLEEPMVDLDG 463
C DVDEC+S C HCTN GSF+CSC GYR R G C+ + E L+G
Sbjct: 764 RC--TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNE---CLEG 818
Query: 464 ELPFVRPLPHIAVLQDE------LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFG 517
+ F PH L + ++ GA + + E L + +C +
Sbjct: 819 DFCF----PHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGS 874
Query: 518 HDC--------------SLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFG-- 561
+C L D+CR G L G C+ G C C P
Sbjct: 875 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG--SYRCVRDCDPGYHAGP 932
Query: 562 -KNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYG---------KHCRKKC 611
C CQ G + GA RC C C GY CR +
Sbjct: 933 EGTCDDVDECQEYG--PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRS 990
Query: 612 NCANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP--HTQSCDKR 667
C C L G+ CLCD G G C EC+ +Q C+
Sbjct: 991 FCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD-------VNECETLQGVCGAALCENV 1043
Query: 668 DGS--CSCKAG------FRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCP 719
+GS C C G G F QA PV + +R
Sbjct: 1044 EGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPV-LPARPPPPPLPRRPS 1102
Query: 720 AGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
QG PVG+ C + A C + + T ++C EG WG
Sbjct: 1103 TPRQG-------PVGSGRRECYFDTAAPDA-CDNILAR-----NVTWQECCCTVGEG-WG 1148
Query: 780 LGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCP--AGWYGPSCQ-------TRC 830
GC+ +C PG + Q +CP G+ PS C
Sbjct: 1149 SGCR--------IQQC----------PGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1190
Query: 831 SCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHW----GPDCSHPCNCSAGHGSCDAIS 886
D C C G+SC C G++ +C C+ +C+
Sbjct: 1191 QLFRDQVCKSGV----CVNTAPGYSCY--CSNGYYYHTQRLECIDNDECADEEPACE--G 1242
Query: 887 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG--------- 937
G C+ G CE G ++RC + D G C G
Sbjct: 1243 GRCVNTVGSYHCTCEPPLVL----DGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPR 1298
Query: 938 --WRGTFCEHACPAG-FFGLDC 956
+ T+ E C G +G+DC
Sbjct: 1299 LDRQATYTECCCLYGEAWGMDC 1320
Score = 160 bits (404), Expect = 1e-38
Identities = 276/1091 (25%), Positives = 353/1091 (32%), Gaps = 217/1091 (19%)
Query: 546 WTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGK 605
+T ++C C G C+ +C+ +N + DS P G G+
Sbjct: 36 FTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGG-----------PGFRAF 84
Query: 606 HCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL----TCPPWAFGPGCSEECQCVQPHT 661
C C+ N G C + CLC P G+FC L PP PG + P
Sbjct: 85 LCPLICH--NGGVCVKP-DRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVY-TMPLA 140
Query: 662 QSCDKRDGSCSCKA-----------------GFRGERCQAECELGYFGPGCWQA-CTCPV 703
D G S + G +A+ E +A P
Sbjct: 141 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 200
Query: 704 GVACDSVSGECGKRCPAGFQ---GEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRC 760
V S E G +GF E G EC G+ C C GA C+
Sbjct: 201 TVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVC-CRGAGLAWGVHDCQL 259
Query: 761 PPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDP----ETGACLCLPGFVGSRCQDV 816
R G P+G G + + +C+ C + G C G G C V
Sbjct: 260 CSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRG--GYTC--V 315
Query: 817 CPAGWYGPSCQTRCSCANDGHCHPATGHC-------SCA-PGWTGFSCQRACDT---GHW 865
CP G+ S +R SC + A G C C+ P + Q C + W
Sbjct: 316 CPDGFLLDS--SRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW 373
Query: 866 GPDCS--HPCN-------CSAGHGSCDAISGL--CLCEAGYVGPRCEQQ----------- 903
G C P C AG G + S L G PR
Sbjct: 374 GRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRP 433
Query: 904 ----CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSA 959
P P E R + G S PA W G + P+ G+ R+
Sbjct: 434 SAGFLPTHRLEPRPEPRPDPRPGPELPLPS----IPA-WTGPEIPESGPSS--GMCQRNP 486
Query: 960 CNCTAGAACDAVNG-SCLCPAGRR----GPRCAETCPAHTYGHNCSQACACFNGASCDPV 1014
C G +G +C C +G R G RC + C+ C N P
Sbjct: 487 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCEN----SPG 541
Query: 1015 HGQCHCAPGW-MGPSCLQACPAGLYGDNCRHSCLCQNGGTCD--PVSGHCACPEGWAGLA 1071
+C C PG+ GP + L D C + G C+ P S C CP G+
Sbjct: 542 SFRCVCGPGFRAGPRAAEC----LDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP 597
Query: 1072 CEKECLPRDVRAGCRHSGGCLNGGLCD--PHTGRCLCPAGWTGDKCQS----------PC 1119
C D C S G G C P + RC+CPAG+ G C+ PC
Sbjct: 598 HGASCQDVD---ECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC 654
Query: 1120 LRGWFGEACAQ-RCSCP-------PGAACHHVTGACRCPPGFTGSGCEQ-------ACP- 1163
G C+CP PGA C V R PP T CE CP
Sbjct: 655 GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPM 714
Query: 1164 ---PGSFGEDCAQM--CQ----CPGENPACHPATGTC-SCAAGYH--------GPSCQQR 1205
P + G +C + C+ CPG+ P + C +C +G+H C
Sbjct: 715 GFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 774
Query: 1206 CPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCG 1263
PP C G C G+ C C G+ P GR GP C V
Sbjct: 775 APP------------CGPHGHCTNTEGSFRCSCAPGY-------RAPSGRPGP-CADVNE 814
Query: 1264 CGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCG 1323
C +G C P G CL G C G G C C LC +G C+
Sbjct: 815 CLEGDFCFP-HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC--QSGICTN- 870
Query: 1324 LGWTGRHCELACPPGRYG----AACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCP 1379
T E CPPG A+C C + C PG Y C C
Sbjct: 871 ---TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY--RCVRDCD 925
Query: 1380 PGFHGAGCQGLC----WCQHGAPCDPISGRCLCPAGFHGHFCERGCEPG---SFGEG--- 1429
PG+H AG +G C CQ P I G C + C C+PG + G G
Sbjct: 926 PGYH-AGPEGTCDDVDECQEYGP--EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQD 982
Query: 1430 ---CHQRCDCDGGAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1484
C R C A C + G CLC G GA C TL C G A
Sbjct: 983 VDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC--VDVNECETLQGVC-GAAL 1039
Query: 1485 CDPVSGQCHCV 1495
C+ V G CV
Sbjct: 1040 CENVEGSFLCV 1050
Score = 159 bits (403), Expect = 2e-38
Identities = 176/640 (27%), Positives = 232/640 (36%), Gaps = 107/640 (16%)
Query: 96 YRQVYTTEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCV--PGSAQPCHCPPG 152
Y + TE C G+ C EC L G CV PGS Q CP G
Sbjct: 698 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSG 757
Query: 153 --FQGPRCQYDVDECRTHNGGC--QHRCVNTPGSYLCECKPGFRLHTDSR-TCLAINSCA 207
RC DVDEC + C C NT GS+ C C PG+R + C +N C
Sbjct: 758 HHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECL 816
Query: 208 LGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR 267
G+ H T C C PG++ G C+ C+ + C G
Sbjct: 817 EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 876
Query: 268 CECHVGYQLAADGKACEDVDECAA-GLAQC-AHGCLNTQGSFKCV--CHAGYELGADGR- 322
C C G++ D +C DVDEC G A C + C N+ GS++CV C GY G +G
Sbjct: 877 CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 936
Query: 323 ----QCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD 378
+C EI + N S+ C+ C GY+ T C DVD+C +
Sbjct: 937 DDVDECQEYGPEICGAQRCENTPGSYRCTPA-------CDPGYQ-PTPGGGCQDVDECRN 988
Query: 379 SPCC--QQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQ 435
C VC N PG ++C C GY + DG C DV+EC + +G C C N+ GSF
Sbjct: 989 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1048
Query: 436 CSCEAGYRLHE----------DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLF 485
C C + G P +P LP P P + P
Sbjct: 1049 CVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL----PRRPSTP 1104
Query: 486 QDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDD--CRNGGTCLLGLDGCDCP 543
+ VG+ E C D+ D CD+ RN + C C
Sbjct: 1105 RQGPVGSGRRE--------------CYFDTAAPD---ACDNILARN-----VTWQECCCT 1142
Query: 544 --EGWTGLICNETCPPDTFGKNCSFSCSCQNG----------------GTC----DSVTG 581
EGW + CP + + C +G C D V
Sbjct: 1143 VGEGWGSGCRIQQCPGT---ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 1199
Query: 582 ACRCPPGVSGTNCEDGCPKGYYGKHCRKKC----NCAN-RGRCHRLYGACLCDPGLYGRF 636
+ C G +C C GYY R +C CA+ C G C+ G Y
Sbjct: 1200 SGVCVNTAPGYSCY--CSNGYYYHTQRLECIDNDECADEEPACEG--GRCVNTVGSY--- 1252
Query: 637 CHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG 676
H TC P G + +CV +QS D G C + G
Sbjct: 1253 -HCTCEPPLVLDG--SQRRCVSNESQSLDDNLGVCWQEVG 1289
Score = 152 bits (384), Expect = 2e-36
Identities = 293/1176 (24%), Positives = 381/1176 (32%), Gaps = 293/1176 (24%)
Query: 270 CHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIE 328
C G++ +CEDVDECA G +C HG C NT+G + CVC G+ L + C I
Sbjct: 277 CPTGFERV--NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSC--IS 331
Query: 329 MEIVNSCEA------NNGGCSHGCSHTSAGPLCTCPR-GYELDTDQRTCIDVDDCADSPC 381
+++ + +GGCS +C C R G + C S
Sbjct: 332 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF----GSEG 387
Query: 382 CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 441
+++C PG + Y G ++ + S+ + + F +
Sbjct: 388 FREICPAGPGYHYSASDLRYNTRPLG---QEPPRVSLSQPRTLPATSRPSAGFLPT---- 440
Query: 442 YRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHI-AVLQDELPQLFQDDDVGADEEEAELR 500
+RL E R P P +L PLP I A E+P+ G + ++
Sbjct: 441 HRL-EPRPEPRPDPRPGPEL--------PLPSIPAWTGPEIPE--SGPSSGMCQRNPQVC 489
Query: 501 GEHTLTEKFVCLDDSFGHDCSLTCDD---CRNGGTCLLGLDGCDCPEGWTGLICNETCPP 557
G C+ G+ C+ CD GT + +D C PP
Sbjct: 490 GPGR------CISRPSGYTCA--CDSGFRLSPQGTRCIDVDEC------------RRVPP 529
Query: 558 DTFGKNC-----SFSCSCQNG-------GTCDSVTGACRCPPGVSGTNCEDG-------C 598
C SF C C G C V R PP CE+ C
Sbjct: 530 PCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVC 589
Query: 599 PKGY----YGKHCRKKCNCA-NRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEE 653
P GY +G C+ C + G C R GAC PG + CP G C E+
Sbjct: 590 PAGYQAAPHGASCQDVDECTQSPGLCGR--GACKNLPGSF----RCVCPAGFRGSACEED 643
Query: 654 C-QCVQPHTQ----SCDKRDGS--CSCKAGFR----GERCQAECELGYFGPGCWQACTCP 702
+C Q CD GS C+C AGFR G CQ E P C
Sbjct: 644 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG---- 699
Query: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCR- 759
C++ G CP GFQ G EC C + +C G C G QCR
Sbjct: 700 ---RCENTEGSFQCVCPMGFQPNTAGSECEDVD---ECENHLACPGQECVNSPGSFQCRT 753
Query: 760 CPPG---RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQ 814
CP G G + D C P C C G+ C C PG+
Sbjct: 754 CPSGHHLHRGRCTDVD--------ECSSGAPPCGPHGHCTNTEGSFRCSCAPGY------ 799
Query: 815 DVCPAGWYGP-----SCQTRCSCANDGHCHPATGH--CSCAPGW----TGFSC------- 856
P+G GP C C G C G C+CAPG+ G SC
Sbjct: 800 -RAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS 858
Query: 857 -QRACDTG-HWGPDCSHPCNCSAGH------GSC----------DAISGLCLCEAGYVGP 898
+ C +G D S C C GH SC A+ G CE
Sbjct: 859 EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 918
Query: 899 RCEQQCPQG-HFGP--GCEQRCQCQHGAACDHVSGACTC---PAGWRGTFCEHACPAGFF 952
RC + C G H GP C+ +CQ + GA C P +R C AC G+
Sbjct: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYG--PEICGAQRCENTPGSYR---CTPACDPGYQ 973
Query: 953 GL---------DCRSACNCTAGAACDAVNGS--CLCPAGRRGPR----CAETCPAHTYGH 997
+CR+ C A A C + GS CLC G G R C + T
Sbjct: 974 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1033
Query: 998 NCSQA----------CACFNG-ASCDPVHGQC--------------------HCAPGWMG 1026
C A C C N DP+ G+C P
Sbjct: 1034 VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPP 1093
Query: 1027 PSCLQACPA----GLYGDNCRHSCLCQNGG--TCDPVSGH--------CACPEGWAGLAC 1072
P L P+ G G R C CD + C EGW G C
Sbjct: 1094 PPPLPRRPSTPRQGPVGSG-RRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGC 1151
Query: 1073 EKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG-----DKCQSPCLRGWFGEA 1127
+ P A + LC PH L P+G D+CQ
Sbjct: 1152 RIQQCPGTETAEYQ--------SLC-PHGRGYLAPSGDLSLRRDVDECQ----------- 1191
Query: 1128 CAQRCSCPPGAACHHVTG-ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHP 1186
+ C G + G +C C G+ + +C +C E PAC
Sbjct: 1192 LFRDQVCKSGVCVNTAPGYSCYCSNGYYYH---------TQRLECIDNDECADEEPACE- 1241
Query: 1187 ATGTCSCAAG-YHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC 1245
G C G YH C C P G ++ C S D G C G
Sbjct: 1242 -GGRCVNTVGSYH---C--TCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVG-----A 1290
Query: 1246 NLTCPQGRFGPNCTHV-CGCGQGAACDPVTGTCLCP 1280
+L C R T+ C C G A LCP
Sbjct: 1291 DLVCSHPRLDRQATYTECCCLYGEAWG--MDCALCP 1324
Score = 151 bits (381), Expect = 5e-36
Identities = 295/1146 (25%), Positives = 370/1146 (32%), Gaps = 303/1146 (26%)
Query: 526 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC 585
D G C L G +C GL E C C+ G V C
Sbjct: 215 DASGFGYCFRELRGGECASPLPGLRTQEVC--------------CRGAGLAWGVHDCQLC 260
Query: 586 PPGVSGT---NCEDG-CPKGY--YGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL 639
+ + + DG CP G+ C CA GRC +G C G Y C
Sbjct: 261 SERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQ--HGECANTRGGYTCVC-- 316
Query: 640 TCPPWAFGPGCSEECQCVQPHTQSCDK-------RDGSCSCK--AGFRGERCQAECELGY 690
P F S C+ H S K RDG CS + C
Sbjct: 317 ---PDGFLLD-SSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKA 372
Query: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAG-----------FQGEDCGQECPVGTFG-- 737
+G GC Q C P G S + CPAG + GQE P +
Sbjct: 373 WGRGC-QLCP-PFG------SEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQP 424
Query: 738 --VNCSSSCSCGGAPCHGVTGQCR-CPPGRTGEDCE---------ADCPEGRWGLGCQEI 785
+ +S S G P H + + P R G + + PE G +
Sbjct: 425 RTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQR 484
Query: 786 CPACQHAARC--DPETGACLCLPGF----VGSRCQDVCPAGWYGPSCQTRCSCANDGHCH 839
P RC P C C GF G+RC DV P C C N
Sbjct: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENS---- 539
Query: 840 PATGHCSCAPGWTGFSCQRAC---DTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAG 894
P + C C PG+ C D H P PC+ G C+ G LC+C AG
Sbjct: 540 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPP---PCDL----GRCENTPGSFLCVCPAG 592
Query: 895 YVGPRCEQQCPQGHFGPGCEQRCQCQHG------AACDHVSGA--CTCPAGWRGTFCEHA 946
Y Q P G C+ +C AC ++ G+ C CPAG+RG+ CE
Sbjct: 593 Y------QAAPH---GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 643
Query: 947 CPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAG--RRGP--------RCAETCPAHT 994
+C CD GS C CPAG RGP CA + P T
Sbjct: 644 VD------ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 697
Query: 995 YGH----NCSQACAC-------FNGASCDPVHGQCHCAPGWMGPSCL--------QACPA 1035
YG S C C G+ C+ V +C G C+ + CP+
Sbjct: 698 YGRCENTEGSFQCVCPMGFQPNTAGSECEDV-DECENHLACPGQECVNSPGSFQCRTCPS 756
Query: 1036 G--LYGDNCRHSCLCQNGG-TCDPVSGHCACPEGWAGLACEKECLPRDVRAG-CRHSGGC 1091
G L+ C C +G C P GHC EG +C R G C C
Sbjct: 757 GHHLHRGRCTDVDECSSGAPPCGP-HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC 815
Query: 1092 LNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPP 1151
L G C PH G CL G + AC C P
Sbjct: 816 LEGDFCFPH-GECLNTDG----------------------------------SFACTCAP 840
Query: 1152 GFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPG-R 1210
G+ PG G C + +C E C +G C+ G S + CPPG R
Sbjct: 841 GYR---------PGPRGASCLDVDEC-SEEDLCQ--SGICTNTDG----SFECICPPGHR 884
Query: 1211 YGPGCEQLCGCLNGGSC----DAATGACRCPTGFLGTDCNLTCPQG-RFGP--NCTHVCG 1263
GP L CL+ C A G+ RC C C G GP C V
Sbjct: 885 AGP---DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 941
Query: 1264 CGQ-------GAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA- 1315
C + C+ G+ C P C+ G Q G GC+ CRN C A
Sbjct: 942 CQEYGPEICGAQRCENTPGSYRCTPA-----CDPGY-QPTPGGGCQDVDECRNRSFCGAH 995
Query: 1316 -------SNGSCSCGLGW----TGRHC----ELACPPGRYGAAC------HLECSCHNN- 1353
+ C C G+ GRHC E G GAA C C N+
Sbjct: 996 AVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSP 1055
Query: 1354 STCEPATGTC---RCGPG-FYGQACEHPCPP--------------------GFHGAGCQG 1389
+P TG C R G F G + P P G G+G +
Sbjct: 1056 EEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-RR 1114
Query: 1390 LCWCQHGAP--CDPISGR------CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAP 1441
C+ AP CD I R C C G +G GC + C G
Sbjct: 1115 ECYFDTAAPDACDNILARNVTWQECCCTVG------------EGWGSGCRIQ-QCPGTET 1161
Query: 1442 CDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCD--CGGGADCDPVSG-QCHCVDGY 1498
+ + LCP GR + D + C L D C G + G C+C +GY
Sbjct: 1162 AEYQS---LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGY 1218
Query: 1499 MGPTCR 1504
T R
Sbjct: 1219 YYHTQR 1224
Score = 147 bits (370), Expect = 1e-34
Identities = 293/1171 (25%), Positives = 395/1171 (33%), Gaps = 235/1171 (20%)
Query: 118 PDEEGCLSAECSASLCFH---GGRC---VPGSAQPCHCPPGFQGPRCQYDVDECRTHNGG 171
P E+G A CF GG C +PG C G +D C G
Sbjct: 208 PREDGYSDAS-GFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGN 266
Query: 172 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP 231
+ V+ P C GF S C ++ CA G G CQH T + C C
Sbjct: 267 SER--VSAPDG---PCPTGFERVNGS--CEDVDECATG-GRCQHGECANTRGGYTCVCPD 318
Query: 232 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-A 290
GF L C+ + + G C +V+R C + + C V +
Sbjct: 319 GFLLDSSRSSCISQHVISEAKGPCF---RVLRD-GGCSLPILRNITKQICCCSRVGKAWG 374
Query: 291 AGLAQCAHGCLNTQGSFKCVCHAG-----------YELGADGRQCYRIEMEIVNSCEANN 339
G C ++G F+ +C AG Y G++ R+ + + A
Sbjct: 375 RGCQLCPP--FGSEG-FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPAT- 430
Query: 340 GGCSHGCSHTSAGPLCTC---PRGYELDTDQRTCIDV--------------DDCADSPCC 382
S SAG L T PR E D R ++ + S C
Sbjct: 431 -------SRPSAGFLPTHRLEPRP-EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMC 482
Query: 383 Q---QVC-----TNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGS 433
Q QVC + P GY C C +G+RLS G C DVDEC C C N GS
Sbjct: 483 QRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGS 542
Query: 434 FQCSCEAGYRLHEDRRGCSPLEE-----PMVDLDGELPFVRPLPHIAVLQDELPQLFQDD 488
F+C C G+R C ++E P DL G P + V P +Q
Sbjct: 543 FRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENT-PGSFLCV----CPAGYQAA 596
Query: 489 DVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG-TCLLGLDGCDCPEGWT 547
GA ++ + +C+ + C G L G C CP G+
Sbjct: 597 PHGASCQDVD--------------------ECTQSPGLCGRGACKNLPGSFRCVCPAGFR 636
Query: 548 GLICNETC------PPDTFGKNC-----SFSCSCQ-------NGGTCDSVTGACRCPPGV 589
G C E PP C SF C+C G C V R PP
Sbjct: 637 GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 696
Query: 590 SGTNCEDG-------CPKGYY----GKHCRKKCNCANRGRCHRLYGACLCDPGLYG-RFC 637
+ CE+ CP G+ G C C N C C+ PG + R C
Sbjct: 697 TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPG--QECVNSPGSFQCRTC 754
Query: 638 ----HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGERCQAECELGYF 691
HL CS PH C +GS CSC G+R G
Sbjct: 755 PSGHHLHRGRCTDVDECSSGAPPCGPHGH-CTNTEGSFRCSCAPGYRAPS-------GRP 806
Query: 692 GP-----GCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN-CSSSCS 745
GP C + C C + G C G++ G C V+ CS
Sbjct: 807 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC----LDVDECSEEDL 862
Query: 746 CGGAPCHGVTG--QCRCPPG-RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC 802
C C G +C CPPG R G D A C + C+E PA + RC+ G+
Sbjct: 863 CQSGICTNTDGSFECICPPGHRAGPDL-ASCLDVD---ECRERGPALCGSQRCENSPGSY 918
Query: 803 LCL----PGFVG---SRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHC--SCAPGW-- 851
C+ PG+ C DV YGP C N P + C +C PG+
Sbjct: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENT----PGSYRCTPACDPGYQP 974
Query: 852 -TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQGH 908
G CQ +C + C A H C + G CLC+ GY G R + C +
Sbjct: 975 TPGGGCQDV-------DECRNRSFCGA-HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1026
Query: 909 FGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA 966
CE A C++V G+ C CP E P + R++ G+
Sbjct: 1027 ---ECETLQGVCGAALCENVEGSFLCVCP-----NSPEEFDPMTGRCVPPRTSAGTFPGS 1078
Query: 967 ACDAVNGSCL-----CPAGRRGPRCAETCPAHTYGHNC----SQACACFNGASCDPVHGQ 1017
A L P R P P + C + AC N + + +
Sbjct: 1079 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQE 1138
Query: 1018 CHC--APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE-K 1074
C C GW +Q CP + + LC +G G+ A P G L +
Sbjct: 1139 CCCTVGEGWGSGCRIQQCPG---TETAEYQSLCPHG------RGYLA-PSGDLSLRRDVD 1188
Query: 1075 EC-LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
EC L RD C+ SG C+N C C G+ + C+ + CA
Sbjct: 1189 ECQLFRD--QVCK-SGVCVN----TAPGYSCYCSNGYYYHTQRLECID---NDECADEEP 1238
Query: 1134 CPPGAACHHVTGA--CRCPPGFTGSGCEQAC 1162
G C + G+ C C P G ++ C
Sbjct: 1239 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
Score = 128 bits (321), Expect = 5e-29
Identities = 145/517 (28%), Positives = 187/517 (36%), Gaps = 120/517 (23%)
Query: 102 TEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCV--PGSAQPCHCPPGFQ-GPR 157
T+ C G+ P CL ECS G C GS + C CPPG + GP
Sbjct: 830 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE-CICPPGHRAGPD 888
Query: 158 CQ--YDVDECRTHNGGC--QHRCVNTPGSYLC--ECKPGFRLHTDSRTCLAINSCA-LGN 210
DVDECR RC N+PGSY C +C PG+ + TC ++ C G
Sbjct: 889 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGP 947
Query: 211 GGCQHHCVQLTITRHRCQ--CRPGFQLQEDGRHCVRRSPCANRNGSCMHR-CQVVRGLAR 267
C + T +RC C PG+Q G C C NR+ H CQ + G +
Sbjct: 948 EICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1006
Query: 268 CECHVGYQLAADGKACEDVDE-------CAAGLAQCAHG-----CLNTQGSF-----KCV 310
C C GY+ A DG+ C DV+E C A L + G C N+ F +CV
Sbjct: 1007 CLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1066
Query: 311 ---CHAGY---------------------------------ELGADGRQCYRIEMEIVNS 334
AG +G+ R+CY + ++
Sbjct: 1067 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY-FDTAAPDA 1125
Query: 335 CE---ANNGGCSHGCSHTSAG-------------------PLCTCPRGYELDT-DQRTCI 371
C+ A N C G LC RGY + D
Sbjct: 1126 CDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR 1185
Query: 372 DVDDCA---DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCE-HHC 427
DVD+C D C VC N GY C C GY C D DECA CE C
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1245
Query: 428 TNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQD 487
N GS+ C+CE L +R C E +D D L +Q
Sbjct: 1246 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD------------------DNLGVCWQ- 1286
Query: 488 DDVGADE--EEAELRGEHTLTEKFVCLDDSFGHDCSL 522
+VGAD L + T TE +++G DC+L
Sbjct: 1287 -EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCAL 1322
Score = 120 bits (301), Expect = 1e-26
Identities = 221/881 (25%), Positives = 281/881 (31%), Gaps = 245/881 (27%)
Query: 670 SCSCKAGFR----GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGE 725
+C+C +GFR G RC E P C G C + P F+
Sbjct: 502 TCACDSGFRLSPQGTRCIDVDECRRVPPPC--------------APGRC-ENSPGSFRCV 546
Query: 726 DCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEI 785
CG G C C P G+C PG C A G CQ++
Sbjct: 547 -CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV 605
Query: 786 CPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS-CAND------GHC 838
Q C GAC LPG RC VCPAG+ G +C+ CA + G C
Sbjct: 606 DECTQSPGLCG--RGACKNLPG--SFRC--VCPAGFRGSACEEDVDECAQEPPPCGPGRC 659
Query: 839 HPATG--HCSCAPGWT----GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL--CL 890
G HC+C G+ G CQ + P C++ G C+ G C+
Sbjct: 660 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY--------GRCENTEGSFQCV 711
Query: 891 CEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAG 950
C G+ +C CE C G C + G+ C CP+G
Sbjct: 712 CPMGFQPNTAGSECEDVD---ECENHLACP-GQECVNSPGSFQC----------RTCPSG 757
Query: 951 --FFGLDCRSACNCTAGAA-------CDAVNGSCLC--------PAGRRGPRCAETCPAH 993
C C++GA C GS C P+GR GP CA+
Sbjct: 758 HHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADV---- 812
Query: 994 TYGHNCSQACACFNGASCDPVHGQ--CHCAPGWM----GPSCLQACPAGLYGDNCRHSCL 1047
+ C + CF C G C CAPG+ G SCL D C L
Sbjct: 813 ---NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDV-------DECSEEDL 862
Query: 1048 CQNGGTCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGL-CD--PHTG 1102
CQ+G C G C CP G CL D CR G L G C+ P +
Sbjct: 863 CQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDE---CRERGPALCGSQRCENSPGSY 918
Query: 1103 RCL--CPAGWTG---------DKCQSPCLRGWFGEAC-AQRCSCPPGAACHHVTGACRCP 1150
RC+ C G+ D+CQ + E C AQRC PG+ + T AC
Sbjct: 919 RCVRDCDPGYHAGPEGTCDDVDECQE-----YGPEICGAQRCENTPGS--YRCTPAC--D 969
Query: 1151 PGFT---GSGCEQA--------------CP--PGSF-------------GEDCAQ----- 1173
PG+ G GC+ C PGSF G C
Sbjct: 970 PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1029
Query: 1174 ------------------MCQCPGENPACHPATGTC----SCAAGYHG--------PSCQ 1203
+C CP P TG C + A + G P
Sbjct: 1030 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1089
Query: 1204 QRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG 1263
R PP P + G + C T C+ + C G
Sbjct: 1090 ARPPP----PPLPRRPSTPRQGPVGSGRRECYFDTA-APDACDNILARNVTWQECCCTVG 1144
Query: 1264 CGQGAACD----PVTGTC----LCPPGRAGVRCERGCPQNRFGVGCE--HTCSCRNGGLC 1313
G G+ C P T T LCP GR + R C+ C++G
Sbjct: 1145 EGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCV 1204
Query: 1314 HASNG-SCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC---EPAT--GTCRCGP 1367
+ + G SC C G+ Y LEC +N C EPA G C
Sbjct: 1205 NTAPGYSCYCSNGY-------------YYHTQRLECI--DNDECADEEPACEGGRCVNTV 1249
Query: 1368 GFYGQACEHPCPPGFHGAGC-----------QGLCWCQHGA 1397
G Y CE P C G+CW + GA
Sbjct: 1250 GSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGA 1290
Score = 110 bits (276), Expect = 8e-24
Identities = 195/733 (26%), Positives = 235/733 (32%), Gaps = 132/733 (18%)
Query: 836 GHCHPATGHCSCAPGWTGFSCQRACDTGH---WGPDCSHPCN-CSAGHGSCDAISGLCLC 891
G+C CA G Q C G WG H C CS G+ + +S
Sbjct: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGV---HDCQLCSERLGNSERVSAPD-- 274
Query: 892 EAGYVGPRCEQQCPQG--HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 949
GP CP G CE +C G C H G C G G C CP
Sbjct: 275 -----GP-----CPTGFERVNGSCEDVDECATGGRCQH--GECANTRG--GYTC--VCPD 318
Query: 950 GFFGLDCRSACNCT-----AGAACDAV--NGSCLCPAGRRGPR--CAETCPAHTYGHNCS 1000
GF RS+C A C V +G C P R + C + +G C
Sbjct: 319 GFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGC- 377
Query: 1001 QACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNG---GTCDPV 1057
Q C F + C PG+ + G L Q T P
Sbjct: 378 QLCPPFGSEGFREI---CPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPS 434
Query: 1058 SGHCAC----------PEGWAGLACEKECLPR----DVRAGCRHSGGCL-NGGLCDPHTG 1102
+G P+ G +P ++ SG C N +C P G
Sbjct: 435 AGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP--G 492
Query: 1103 RCLC-PAGWTGDKCQSPCLRGWFGEACAQRCSC---PPGAACHHVTGACRCPPGFTGSGC 1158
RC+ P+G+T C S G C C PP A G C PG C
Sbjct: 493 RCISRPSGYTC-ACDSGFRLSPQGTRCIDVDECRRVPPPCA----PGRCENSPGSFRCVC 547
Query: 1159 EQACPPGSFGEDCAQMCQCPGENPACH-------PATGTCSCAAGY----HGPSCQQRCP 1207
G +C + +C P C P + C C AGY HG SCQ
Sbjct: 548 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV-- 605
Query: 1208 PGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCG 1265
C Q G G+C G+ C CP GF G+ C + P CG
Sbjct: 606 -----DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPP-----PCG 655
Query: 1266 QGAACDPVTGT--CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG------GLCHASN 1317
G CD G+ C CP AG R RG G C+ C G C +
Sbjct: 656 PGR-CDNTAGSFHCACP---AGFR-SRGP-----GAPCQDVDECARSPPPCTYGRCENTE 705
Query: 1318 GSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHP 1377
GS C C + P G+ C C N+ C C PG + C
Sbjct: 706 GSFQCV-------CPMGFQPNTAGSECEDVDECENHLACPGQE--CVNSPGSF--QCR-T 753
Query: 1378 CPPG--FHGAGCQGLCWCQHGAP-CDPISGRCLCPAGFHGHFCERGCEPGSFGEG-CHQR 1433
CP G H C + C GAP C P G C G C G S G C
Sbjct: 754 CPSGHHLHRGRCTDVDECSSGAPPCGP-HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 812
Query: 1434 CDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCH 1493
+C G C P G CL G TC R G G SC +C C SG C
Sbjct: 813 NECLEGDFCFP-HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ--SGICT 869
Query: 1494 CVDGYMGPTCREG 1506
DG C G
Sbjct: 870 NTDGSFECICPPG 882
Score = 89.7 bits (221), Expect = 2e-17
Identities = 211/880 (23%), Positives = 270/880 (30%), Gaps = 183/880 (20%)
Query: 712 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA 771
G G+R F CG C G G C+ +C+ P T D A
Sbjct: 26 GRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCA---------------PRNATSVDSGA 70
Query: 772 DCPEGRWGLGCQE-ICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRC 830
G G + +CP H + CLC P F G CQ + P
Sbjct: 71 PGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDFAGKFCQ--LHSSGARPPAPAVP 128
Query: 831 SCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCL 890
+ P H G HP S + +SG
Sbjct: 129 GLTRSVYTMPLANHRDDEHGVASMVSVHV----------EHPQEASVVVHQVERVSGPWE 178
Query: 891 CEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAG 950
R E P SG C RG C P
Sbjct: 179 EADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLP-- 236
Query: 951 FFGLDCRSACNCTAGAA--------CDAVNGSCLCPAGRRGPRCAETCPA--HTYGHNCS 1000
GL + C AG A C G+ + GP CP +C
Sbjct: 237 --GLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP-----CPTGFERVNGSCE 289
Query: 1001 QACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQN-----GGTCD 1055
C G C HG+C G G +C+ CP G D+ R SC+ Q+ G C
Sbjct: 290 DVDECATGGRCQ--HGECANTRG--GYTCV--CPDGFLLDSSRSSCISQHVISEAKGPCF 343
Query: 1056 PV--SGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG---RCLCPAGW 1110
V G C+ P + + C R +A R GC LC P R +CPAG
Sbjct: 344 RVLRDGGCSLPI-LRNITKQICCCSRVGKAWGR---GC---QLCPPFGSEGFREICPAG- 395
Query: 1111 TGDKCQSPCLRGWFGEACAQRCSCPPGAACHH---VTGACRCPPGFTGS----------- 1156
G + LR + Q PP + + R GF +
Sbjct: 396 PGYHYSASDLR-YNTRPLGQE---PPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRP 451
Query: 1157 ----GCEQACP--PGSFGEDCAQ------MCQ-----CPGENPACHPATGTCSCAAGY-- 1197
G E P P G + + MCQ C P+ TC+C +G+
Sbjct: 452 DPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRL 511
Query: 1198 --HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFG 1255
G C R P C G C+ + G+ RC G P R G
Sbjct: 512 SPQGTRCIDVDECRRVPPPCAP-------GRCENSPGSFRCVCG----------PGFRAG 554
Query: 1256 P---NCTHVCGCGQ-GAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSC-RNG 1310
P C V C + CD G C PG C G G C+ C ++
Sbjct: 555 PRAAECLDVDECHRVPPPCD--LGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSP 612
Query: 1311 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY 1370
GLC G+C G CP G G+AC + E A CGPG
Sbjct: 613 GLC--GRGACKNLPG----SFRCVCPAGFRGSACEEDVD-------ECAQEPPPCGPG-- 657
Query: 1371 GQACEH-------PCPPGFH----GAGCQGLCWCQHGAPCDPIS-GRCLCPAGFHGHFCE 1418
C++ CP GF GA CQ + C P P + GRC G C
Sbjct: 658 --RCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP--PCTYGRCENTEGSFQCVCP 713
Query: 1419 RGCEPGSFGEGCHQRCDCDGGAPC-------DPVTGLC-LCPPG----RSGATCNLDCRR 1466
G +P + G C +C+ C P + C CP G R T +C
Sbjct: 714 MGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSS 773
Query: 1467 GQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREG 1506
G P C H C S +C C GY P+ R G
Sbjct: 774 G--APPCGPHGHCTNTEG----SFRCSCAPGYRAPSGRPG 807
Score = 56.2 bits (134), Expect = 2e-07
Identities = 73/304 (24%), Positives = 100/304 (32%), Gaps = 62/304 (20%)
Query: 132 LCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGF 191
+C +GG CV C CPP F G CQ H+ G + PG
Sbjct: 89 ICHNGGVCV--KPDRCLCPPDFAGKFCQL-------HSSGARPPAPAVPGLTRSVYTMPL 139
Query: 192 RLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANR 251
H D +A H + ++ H+ + R +E V R+ A
Sbjct: 140 ANHRDDEHGVASMVSVH-----VEHPQEASVVVHQVE-RVSGPWEEADAEAVARAEAA-- 191
Query: 252 NGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLA---------QCAHGCLN 302
AR E Y + A ED A+G +CA
Sbjct: 192 --------------ARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPG 237
Query: 303 TQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH--GCSHTSAGPLCTCPRG 360
+ C AG G V+ C+ CS G S + P CP G
Sbjct: 238 LRTQEVCCRGAGLAWG-------------VHDCQL----CSERLGNSERVSAPDGPCPTG 280
Query: 361 YELDTDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 419
+E +C DVD+CA CQ C N GGY C C G+ L + C + +
Sbjct: 281 FERVNG--SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA 338
Query: 420 RGGC 423
+G C
Sbjct: 339 KGPC 342
Score = 54.7 bits (130), Expect = 7e-07
Identities = 49/137 (35%), Positives = 58/137 (42%), Gaps = 21/137 (15%)
Query: 105 RTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQ--GPRCQYDV 162
RT CCRG C CS L G SA CP GF+ C+ DV
Sbjct: 239 RTQEVCCRGAGLAWGVHDCQL--CSERL----GNSERVSAPDGPCPTGFERVNGSCE-DV 291
Query: 163 DECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCL-------AINSC--ALGNGG 212
DEC T G CQH C NT G Y C C GF L + +C+ A C L +GG
Sbjct: 292 DECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGG 350
Query: 213 CQHHCVQLTITRHRCQC 229
C ++ IT+ C C
Sbjct: 351 CSLPILR-NITKQICCC 366
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 156 PRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGG--- 212
P + + +EC +G RCV P + C C G+RL C+ IN C
Sbjct: 1461 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1520
Query: 213 CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCA 249
C + T RC CRPGF HC P A
Sbjct: 1521 CVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
Score = 53.9 bits (128), Expect = 1e-06
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 381 CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC----ASSRGGCEHHCTNLAGSFQC 436
C C P G+ C C+ GYRL C D++EC A+S C N GSF+C
Sbjct: 1476 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1535
Query: 437 SCEAGYRLHEDRRGCSP 453
C G+ C+P
Sbjct: 1536 ICRPGFAPTHQPHHCAP 1552
Score = 52.4 bits (124), Expect = 3e-06
Identities = 60/213 (28%), Positives = 78/213 (36%), Gaps = 46/213 (21%)
Query: 24 PAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQ---------PCVQALSHTVPVWK 74
PA PV + PP P LP +P P Q GRR+ C L+ V W+
Sbjct: 1083 PASPVLPARPPPPPLPRRPSTPR----QGPVGSGRRECYFDTAAPDACDNILARNV-TWQ 1137
Query: 75 AGC-----GWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCC---RGWMQQPDEEGCLSA 126
C GW + C +Q TE C RG++ P + L
Sbjct: 1138 ECCCTVGEGWGSGC-----------RIQQCPGTETAEYQSLCPHGRGYLA-PSGDLSLRR 1185
Query: 127 ECSASLCFHGGRCVPG------SAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQH-R 175
+ F C G C+C G+ Q C D DEC C+ R
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC-IDNDECADEEPACEGGR 1244
Query: 176 CVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL 208
CVNT GSY C C+P L R C++ S +L
Sbjct: 1245 CVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSL 1277
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 248 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC---AAGLAQCAHG-CLNT 303
C +G RC V C C GY+L AC D++EC A C + CLNT
Sbjct: 1470 CGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNT 1529
Query: 304 QGSFKCVCHAGY 315
GSF+C+C G+
Sbjct: 1530 DGSFRCICRPGF 1541
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 341 GCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC----ADSPCCQQV-CTNNPGGYE 394
GC++G C G C C GY LD + C+D+++C A SP C C N G +
Sbjct: 1475 GCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1534
Query: 395 CGCYAGY 401
C C G+
Sbjct: 1535 CICRPGF 1541
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 24/150 (16%)
Query: 285 DVDECAAGLAQ-CAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC 342
DVDEC Q C G C+NT + C C GY +C + C C
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND-----ECADEEPAC 1240
Query: 343 SHG-CSHTSAGPLCTCPRGYELDTDQRTCI-----DVDD----C-----ADSPCCQQVCT 387
G C +T CTC LD QR C+ +DD C AD C
Sbjct: 1241 EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLD 1300
Query: 388 NNPGGYECGCYAGYRLSADG--CGCEDVDE 415
EC C G D C +D D+
Sbjct: 1301 RQATYTECCCLYGEAWGMDCALCPAQDSDD 1330
Score = 33.9 bits (76), Expect = 1.3
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 14/69 (20%)
Query: 394 ECGCYAGY------RLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED 447
E G YAG L A+ CG +D C + R C + F C C GYRL
Sbjct: 1450 EGGSYAGSLAEPYEELEAEECGI--LDGCTNGR------CVRVPEGFTCRCFDGYRLDMT 1501
Query: 448 RRGCSPLEE 456
R C + E
Sbjct: 1502 RMACVDINE 1510
Score = 31.2 bits (69), Expect = 8.1
Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 5/79 (6%)
Query: 285 DVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS 343
+ +EC L C +G C+ F C C GY L C +++ + EA + C
Sbjct: 1466 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC--VDINECDEAEAASPLCV 1522
Query: 344 HG-CSHTSAGPLCTCPRGY 361
+ C +T C C G+
Sbjct: 1523 NARCLNTDGSFRCICRPGF 1541
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 233 bits (594), Expect = 1e-60
Identities = 252/922 (27%), Positives = 334/922 (36%), Gaps = 160/922 (17%)
Query: 120 EEGCLSAECSASLCFHG-GRCVPG-SAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQ 173
E G S C + G GRC+ S C C GF QG RC DVDECR C
Sbjct: 504 ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA 562
Query: 174 H-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232
RC N+PGS+ C C PGFR + CL ++ C C + T C C G
Sbjct: 563 PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAG 622
Query: 233 FQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACE-DVDECA 290
+Q G C C G C C+ + G RC C G++ G ACE DVDECA
Sbjct: 623 YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECA 678
Query: 291 AGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSH 348
C G C NT GSF C C AG+ G C + V+ C + C++G C +
Sbjct: 679 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC-----QDVDECARSPPPCTYGRCEN 733
Query: 349 TSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECG-CYAGYRLSAD 406
T C CP G++ +T C DVD+C + C Q C N+PG ++C C +G+ L
Sbjct: 734 TEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 793
Query: 407 GCGCEDVDECASSRGGC--EHHCTNLAGSFQCSCEAGYRLHEDRRG-CSPLEEPMVDLDG 463
C DVDEC+S C HCTN GSF+CSC GYR R G C+ + E L+G
Sbjct: 794 RC--TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNE---CLEG 848
Query: 464 ELPFVRPLPHIAVLQDE------LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFG 517
+ F PH L + ++ GA + + E L + +C +
Sbjct: 849 DFCF----PHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGS 904
Query: 518 HDC--------------SLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFG-- 561
+C L D+CR G L G C+ G C C P
Sbjct: 905 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG--SYRCVRDCDPGYHAGP 962
Query: 562 -KNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYG---------KHCRKKC 611
C CQ G + GA RC C C GY CR +
Sbjct: 963 EGTCDDVDECQEYG--PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRS 1020
Query: 612 NCANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP--HTQSCDKR 667
C C L G+ CLCD G G C EC+ +Q C+
Sbjct: 1021 FCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD-------VNECETLQGVCGAALCENV 1073
Query: 668 DGS--CSCKAG------FRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCP 719
+GS C C G G F QA PV + +R
Sbjct: 1074 EGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPV-LPARPPPPPLPRRPS 1132
Query: 720 AGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
QG PVG+ C + A C + + T ++C EG WG
Sbjct: 1133 TPRQG-------PVGSGRRECYFDTAAPDA-CDNILAR-----NVTWQECCCTVGEG-WG 1178
Query: 780 LGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCP--AGWYGPSCQ-------TRC 830
GC+ +C PG + Q +CP G+ PS C
Sbjct: 1179 SGCR--------IQQC----------PGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1220
Query: 831 SCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHW----GPDCSHPCNCSAGHGSCDAIS 886
D C C G+SC C G++ +C C+ +C+
Sbjct: 1221 QLFRDQVCKSGV----CVNTAPGYSCY--CSNGYYYHTQRLECIDNDECADEEPACE--G 1272
Query: 887 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG--------- 937
G C+ G CE G ++RC + D G C G
Sbjct: 1273 GRCVNTVGSYHCTCEPPLVL----DGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPR 1328
Query: 938 --WRGTFCEHACPAG-FFGLDC 956
+ T+ E C G +G+DC
Sbjct: 1329 LDRQATYTECCCLYGEAWGMDC 1350
Score = 159 bits (403), Expect = 2e-38
Identities = 176/640 (27%), Positives = 232/640 (36%), Gaps = 107/640 (16%)
Query: 96 YRQVYTTEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCV--PGSAQPCHCPPG 152
Y + TE C G+ C EC L G CV PGS Q CP G
Sbjct: 728 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSG 787
Query: 153 --FQGPRCQYDVDECRTHNGGC--QHRCVNTPGSYLCECKPGFRLHTDSR-TCLAINSCA 207
RC DVDEC + C C NT GS+ C C PG+R + C +N C
Sbjct: 788 HHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECL 846
Query: 208 LGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR 267
G+ H T C C PG++ G C+ C+ + C G
Sbjct: 847 EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 906
Query: 268 CECHVGYQLAADGKACEDVDECAA-GLAQC-AHGCLNTQGSFKCV--CHAGYELGADGR- 322
C C G++ D +C DVDEC G A C + C N+ GS++CV C GY G +G
Sbjct: 907 CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 966
Query: 323 ----QCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD 378
+C EI + N S+ C+ C GY+ T C DVD+C +
Sbjct: 967 DDVDECQEYGPEICGAQRCENTPGSYRCTPA-------CDPGYQ-PTPGGGCQDVDECRN 1018
Query: 379 SPCC--QQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQ 435
C VC N PG ++C C GY + DG C DV+EC + +G C C N+ GSF
Sbjct: 1019 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1078
Query: 436 CSCEAGYRLHE----------DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLF 485
C C + G P +P LP P P + P
Sbjct: 1079 CVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL----PRRPSTP 1134
Query: 486 QDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDD--CRNGGTCLLGLDGCDCP 543
+ VG+ E C D+ D CD+ RN + C C
Sbjct: 1135 RQGPVGSGRRE--------------CYFDTAAPD---ACDNILARN-----VTWQECCCT 1172
Query: 544 --EGWTGLICNETCPPDTFGKNCSFSCSCQNG----------------GTC----DSVTG 581
EGW + CP + + C +G C D V
Sbjct: 1173 VGEGWGSGCRIQQCPGT---ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 1229
Query: 582 ACRCPPGVSGTNCEDGCPKGYYGKHCRKKC----NCAN-RGRCHRLYGACLCDPGLYGRF 636
+ C G +C C GYY R +C CA+ C G C+ G Y
Sbjct: 1230 SGVCVNTAPGYSCY--CSNGYYYHTQRLECIDNDECADEEPACEG--GRCVNTVGSY--- 1282
Query: 637 CHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG 676
H TC P G + +CV +QS D G C + G
Sbjct: 1283 -HCTCEPPLVLDG--SQRRCVSNESQSLDDNLGVCWQEVG 1319
Score = 152 bits (384), Expect = 2e-36
Identities = 293/1176 (24%), Positives = 381/1176 (32%), Gaps = 293/1176 (24%)
Query: 270 CHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIE 328
C G++ +CEDVDECA G +C HG C NT+G + CVC G+ L + C I
Sbjct: 307 CPTGFERV--NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSC--IS 361
Query: 329 MEIVNSCEA------NNGGCSHGCSHTSAGPLCTCPR-GYELDTDQRTCIDVDDCADSPC 381
+++ + +GGCS +C C R G + C S
Sbjct: 362 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF----GSEG 417
Query: 382 CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 441
+++C PG + Y G ++ + S+ + + F +
Sbjct: 418 FREICPAGPGYHYSASDLRYNTRPLG---QEPPRVSLSQPRTLPATSRPSAGFLPT---- 470
Query: 442 YRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHI-AVLQDELPQLFQDDDVGADEEEAELR 500
+RL E R P P +L PLP I A E+P+ G + ++
Sbjct: 471 HRL-EPRPEPRPDPRPGPEL--------PLPSIPAWTGPEIPE--SGPSSGMCQRNPQVC 519
Query: 501 GEHTLTEKFVCLDDSFGHDCSLTCDD---CRNGGTCLLGLDGCDCPEGWTGLICNETCPP 557
G C+ G+ C+ CD GT + +D C PP
Sbjct: 520 GPGR------CISRPSGYTCA--CDSGFRLSPQGTRCIDVDEC------------RRVPP 559
Query: 558 DTFGKNC-----SFSCSCQNG-------GTCDSVTGACRCPPGVSGTNCEDG-------C 598
C SF C C G C V R PP CE+ C
Sbjct: 560 PCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVC 619
Query: 599 PKGY----YGKHCRKKCNCA-NRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEE 653
P GY +G C+ C + G C R GAC PG + CP G C E+
Sbjct: 620 PAGYQAAPHGASCQDVDECTQSPGLCGR--GACKNLPGSF----RCVCPAGFRGSACEED 673
Query: 654 C-QCVQPHTQ----SCDKRDGS--CSCKAGFR----GERCQAECELGYFGPGCWQACTCP 702
+C Q CD GS C+C AGFR G CQ E P C
Sbjct: 674 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG---- 729
Query: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCR- 759
C++ G CP GFQ G EC C + +C G C G QCR
Sbjct: 730 ---RCENTEGSFQCVCPMGFQPNTAGSECEDVD---ECENHLACPGQECVNSPGSFQCRT 783
Query: 760 CPPG---RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQ 814
CP G G + D C P C C G+ C C PG+
Sbjct: 784 CPSGHHLHRGRCTDVD--------ECSSGAPPCGPHGHCTNTEGSFRCSCAPGY------ 829
Query: 815 DVCPAGWYGP-----SCQTRCSCANDGHCHPATGH--CSCAPGW----TGFSC------- 856
P+G GP C C G C G C+CAPG+ G SC
Sbjct: 830 -RAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS 888
Query: 857 -QRACDTG-HWGPDCSHPCNCSAGH------GSC----------DAISGLCLCEAGYVGP 898
+ C +G D S C C GH SC A+ G CE
Sbjct: 889 EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 948
Query: 899 RCEQQCPQG-HFGP--GCEQRCQCQHGAACDHVSGACTC---PAGWRGTFCEHACPAGFF 952
RC + C G H GP C+ +CQ + GA C P +R C AC G+
Sbjct: 949 RCVRDCDPGYHAGPEGTCDDVDECQEYG--PEICGAQRCENTPGSYR---CTPACDPGYQ 1003
Query: 953 GL---------DCRSACNCTAGAACDAVNGS--CLCPAGRRGPR----CAETCPAHTYGH 997
+CR+ C A A C + GS CLC G G R C + T
Sbjct: 1004 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1063
Query: 998 NCSQA----------CACFNG-ASCDPVHGQC--------------------HCAPGWMG 1026
C A C C N DP+ G+C P
Sbjct: 1064 VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPP 1123
Query: 1027 PSCLQACPA----GLYGDNCRHSCLCQNGG--TCDPVSGH--------CACPEGWAGLAC 1072
P L P+ G G R C CD + C EGW G C
Sbjct: 1124 PPPLPRRPSTPRQGPVGSG-RRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGC 1181
Query: 1073 EKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG-----DKCQSPCLRGWFGEA 1127
+ P A + LC PH L P+G D+CQ
Sbjct: 1182 RIQQCPGTETAEYQ--------SLC-PHGRGYLAPSGDLSLRRDVDECQ----------- 1221
Query: 1128 CAQRCSCPPGAACHHVTG-ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHP 1186
+ C G + G +C C G+ + +C +C E PAC
Sbjct: 1222 LFRDQVCKSGVCVNTAPGYSCYCSNGYYYH---------TQRLECIDNDECADEEPACE- 1271
Query: 1187 ATGTCSCAAG-YHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC 1245
G C G YH C C P G ++ C S D G C G
Sbjct: 1272 -GGRCVNTVGSYH---C--TCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVG-----A 1320
Query: 1246 NLTCPQGRFGPNCTHV-CGCGQGAACDPVTGTCLCP 1280
+L C R T+ C C G A LCP
Sbjct: 1321 DLVCSHPRLDRQATYTECCCLYGEAWG--MDCALCP 1354
Score = 152 bits (383), Expect = 3e-36
Identities = 263/1024 (25%), Positives = 331/1024 (32%), Gaps = 204/1024 (19%)
Query: 613 CANRGRCHRLYGACLCDPGLYGRFCHLTC----PPWAFGPGCSEECQCVQPHTQSCDKRD 668
C N G C + CLC P G+FC L PP PG + + P D
Sbjct: 120 CHNGGVCVKP-DRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTM-PLANHRDDEH 177
Query: 669 GSCSCKA-----------------GFRGERCQAECELGYFGPGCWQA-CTCPVGVACDSV 710
G S + G +A+ E +A P V S
Sbjct: 178 GVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSA 237
Query: 711 SGECGKRCPAGFQ---GEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGE 767
E G +GF E G EC G+ C G GV C+ R G
Sbjct: 238 PREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVH-DCQLCSERLGN 296
Query: 768 DCEADCPEGRWGLGCQEICPACQHAARCDP----ETGACLCLPGFVGSRCQDVCPAGWYG 823
P+G G + + +C+ C + G C G G C VCP G+
Sbjct: 297 SERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRG--GYTC--VCPDGFLL 352
Query: 824 PSCQTRCSCANDGHCHPATGHC-------SCA-PGWTGFSCQRACDT---GHWGPDCS-- 870
S +R SC + A G C C+ P + Q C + WG C
Sbjct: 353 DS--SRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLC 410
Query: 871 HPCN-------CSAGHGSCDAISGL--CLCEAGYVGPRCEQQ---------------CPQ 906
P C AG G + S L G PR P
Sbjct: 411 PPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPT 470
Query: 907 GHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA 966
P E R + G S PA W G + P+ G+ R+ C G
Sbjct: 471 HRLEPRPEPRPDPRPGPELPLPS----IPA-WTGPEIPESGPSS--GMCQRNPQVCGPGR 523
Query: 967 ACDAVNG-SCLCPAGRR----GPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCA 1021
+G +C C +G R G RC + C+ C N P +C C
Sbjct: 524 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCEN----SPGSFRCVCG 578
Query: 1022 PGW-MGPSCLQACPAGLYGDNCRHSCLCQNGGTCD--PVSGHCACPEGWAGLACEKECLP 1078
PG+ GP + L D C + G C+ P S C CP G+ C
Sbjct: 579 PGFRAGPRAAEC----LDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 634
Query: 1079 RDVRAGCRHSGGCLNGGLCD--PHTGRCLCPAGWTGDKCQS----------PCLRGWFGE 1126
D C S G G C P + RC+CPAG+ G C+ PC G
Sbjct: 635 VD---ECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDN 691
Query: 1127 ACAQ-RCSCP-------PGAACHHVTGACRCPPGFTGSGCEQ-------ACP----PGSF 1167
C+CP PGA C V R PP T CE CP P +
Sbjct: 692 TAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTA 751
Query: 1168 GEDCAQM--CQ----CPGENPACHPATGTC-SCAAGYH--------GPSCQQRCPPGRYG 1212
G +C + C+ CPG+ P + C +C +G+H C PP
Sbjct: 752 GSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPP---- 807
Query: 1213 PGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC 1270
C G C G+ C C G+ P GR GP C V C +G C
Sbjct: 808 --------CGPHGHCTNTEGSFRCSCAPGY-------RAPSGRPGP-CADVNECLEGDFC 851
Query: 1271 DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRH 1330
P G CL G C G G C C LC +G C+ T
Sbjct: 852 FP-HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC--QSGICTN----TDGS 904
Query: 1331 CELACPPGRYG----AACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAG 1386
E CPPG A+C C + C PG Y C C PG+H AG
Sbjct: 905 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY--RCVRDCDPGYH-AG 961
Query: 1387 CQGLC----WCQHGAPCDPISGRCLCPAGFHGHFCERGCEPG---SFGEG------CHQR 1433
+G C CQ P I G C + C C+PG + G G C R
Sbjct: 962 PEGTCDDVDECQEYGP--EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR 1019
Query: 1434 CDCDGGAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ 1491
C A C + G CLC G GA C TL C G A C+ V G
Sbjct: 1020 SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC--VDVNECETLQGVC-GAALCENVEGS 1076
Query: 1492 CHCV 1495
CV
Sbjct: 1077 FLCV 1080
Score = 151 bits (381), Expect = 5e-36
Identities = 295/1146 (25%), Positives = 370/1146 (32%), Gaps = 303/1146 (26%)
Query: 526 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC 585
D G C L G +C GL E C C+ G V C
Sbjct: 245 DASGFGYCFRELRGGECASPLPGLRTQEVC--------------CRGAGLAWGVHDCQLC 290
Query: 586 PPGVSGT---NCEDG-CPKGY--YGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL 639
+ + + DG CP G+ C CA GRC +G C G Y C
Sbjct: 291 SERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQ--HGECANTRGGYTCVC-- 346
Query: 640 TCPPWAFGPGCSEECQCVQPHTQSCDK-------RDGSCSCK--AGFRGERCQAECELGY 690
P F S C+ H S K RDG CS + C
Sbjct: 347 ---PDGFLLD-SSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKA 402
Query: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAG-----------FQGEDCGQECPVGTFG-- 737
+G GC Q C P G S + CPAG + GQE P +
Sbjct: 403 WGRGC-QLCP-PFG------SEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQP 454
Query: 738 --VNCSSSCSCGGAPCHGVTGQCR-CPPGRTGEDCE---------ADCPEGRWGLGCQEI 785
+ +S S G P H + + P R G + + PE G +
Sbjct: 455 RTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQR 514
Query: 786 CPACQHAARC--DPETGACLCLPGF----VGSRCQDVCPAGWYGPSCQTRCSCANDGHCH 839
P RC P C C GF G+RC DV P C C N
Sbjct: 515 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENS---- 569
Query: 840 PATGHCSCAPGWTGFSCQRAC---DTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAG 894
P + C C PG+ C D H P PC+ G C+ G LC+C AG
Sbjct: 570 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPP---PCDL----GRCENTPGSFLCVCPAG 622
Query: 895 YVGPRCEQQCPQGHFGPGCEQRCQCQHG------AACDHVSGA--CTCPAGWRGTFCEHA 946
Y Q P G C+ +C AC ++ G+ C CPAG+RG+ CE
Sbjct: 623 Y------QAAPH---GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 673
Query: 947 CPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAG--RRGP--------RCAETCPAHT 994
+C CD GS C CPAG RGP CA + P T
Sbjct: 674 VD------ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 727
Query: 995 YGH----NCSQACAC-------FNGASCDPVHGQCHCAPGWMGPSCL--------QACPA 1035
YG S C C G+ C+ V +C G C+ + CP+
Sbjct: 728 YGRCENTEGSFQCVCPMGFQPNTAGSECEDV-DECENHLACPGQECVNSPGSFQCRTCPS 786
Query: 1036 G--LYGDNCRHSCLCQNGG-TCDPVSGHCACPEGWAGLACEKECLPRDVRAG-CRHSGGC 1091
G L+ C C +G C P GHC EG +C R G C C
Sbjct: 787 GHHLHRGRCTDVDECSSGAPPCGP-HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC 845
Query: 1092 LNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPP 1151
L G C PH G CL G + AC C P
Sbjct: 846 LEGDFCFPH-GECLNTDG----------------------------------SFACTCAP 870
Query: 1152 GFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPG-R 1210
G+ PG G C + +C E C +G C+ G S + CPPG R
Sbjct: 871 GYR---------PGPRGASCLDVDEC-SEEDLCQ--SGICTNTDG----SFECICPPGHR 914
Query: 1211 YGPGCEQLCGCLNGGSC----DAATGACRCPTGFLGTDCNLTCPQG-RFGP--NCTHVCG 1263
GP L CL+ C A G+ RC C C G GP C V
Sbjct: 915 AGP---DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 971
Query: 1264 CGQ-------GAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA- 1315
C + C+ G+ C P C+ G Q G GC+ CRN C A
Sbjct: 972 CQEYGPEICGAQRCENTPGSYRCTPA-----CDPGY-QPTPGGGCQDVDECRNRSFCGAH 1025
Query: 1316 -------SNGSCSCGLGW----TGRHC----ELACPPGRYGAAC------HLECSCHNN- 1353
+ C C G+ GRHC E G GAA C C N+
Sbjct: 1026 AVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSP 1085
Query: 1354 STCEPATGTC---RCGPG-FYGQACEHPCPP--------------------GFHGAGCQG 1389
+P TG C R G F G + P P G G+G +
Sbjct: 1086 EEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-RR 1144
Query: 1390 LCWCQHGAP--CDPISGR------CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAP 1441
C+ AP CD I R C C G +G GC + C G
Sbjct: 1145 ECYFDTAAPDACDNILARNVTWQECCCTVG------------EGWGSGCRIQ-QCPGTET 1191
Query: 1442 CDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCD--CGGGADCDPVSG-QCHCVDGY 1498
+ + LCP GR + D + C L D C G + G C+C +GY
Sbjct: 1192 AEYQS---LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGY 1248
Query: 1499 MGPTCR 1504
T R
Sbjct: 1249 YYHTQR 1254
Score = 147 bits (370), Expect = 1e-34
Identities = 293/1171 (25%), Positives = 395/1171 (33%), Gaps = 235/1171 (20%)
Query: 118 PDEEGCLSAECSASLCFH---GGRC---VPGSAQPCHCPPGFQGPRCQYDVDECRTHNGG 171
P E+G A CF GG C +PG C G +D C G
Sbjct: 238 PREDGYSDAS-GFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGN 296
Query: 172 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP 231
+ V+ P C GF S C ++ CA G G CQH T + C C
Sbjct: 297 SER--VSAPDG---PCPTGFERVNGS--CEDVDECATG-GRCQHGECANTRGGYTCVCPD 348
Query: 232 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-A 290
GF L C+ + + G C +V+R C + + C V +
Sbjct: 349 GFLLDSSRSSCISQHVISEAKGPCF---RVLRD-GGCSLPILRNITKQICCCSRVGKAWG 404
Query: 291 AGLAQCAHGCLNTQGSFKCVCHAG-----------YELGADGRQCYRIEMEIVNSCEANN 339
G C ++G F+ +C AG Y G++ R+ + + A
Sbjct: 405 RGCQLCPP--FGSEG-FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPAT- 460
Query: 340 GGCSHGCSHTSAGPLCTC---PRGYELDTDQRTCIDV--------------DDCADSPCC 382
S SAG L T PR E D R ++ + S C
Sbjct: 461 -------SRPSAGFLPTHRLEPRP-EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMC 512
Query: 383 Q---QVC-----TNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGS 433
Q QVC + P GY C C +G+RLS G C DVDEC C C N GS
Sbjct: 513 QRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGS 572
Query: 434 FQCSCEAGYRLHEDRRGCSPLEE-----PMVDLDGELPFVRPLPHIAVLQDELPQLFQDD 488
F+C C G+R C ++E P DL G P + V P +Q
Sbjct: 573 FRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENT-PGSFLCV----CPAGYQAA 626
Query: 489 DVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG-TCLLGLDGCDCPEGWT 547
GA ++ + +C+ + C G L G C CP G+
Sbjct: 627 PHGASCQDVD--------------------ECTQSPGLCGRGACKNLPGSFRCVCPAGFR 666
Query: 548 GLICNETC------PPDTFGKNC-----SFSCSCQ-------NGGTCDSVTGACRCPPGV 589
G C E PP C SF C+C G C V R PP
Sbjct: 667 GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 726
Query: 590 SGTNCEDG-------CPKGYY----GKHCRKKCNCANRGRCHRLYGACLCDPGLYG-RFC 637
+ CE+ CP G+ G C C N C C+ PG + R C
Sbjct: 727 TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPG--QECVNSPGSFQCRTC 784
Query: 638 ----HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGERCQAECELGYF 691
HL CS PH C +GS CSC G+R G
Sbjct: 785 PSGHHLHRGRCTDVDECSSGAPPCGPHGH-CTNTEGSFRCSCAPGYRAPS-------GRP 836
Query: 692 GP-----GCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN-CSSSCS 745
GP C + C C + G C G++ G C V+ CS
Sbjct: 837 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC----LDVDECSEEDL 892
Query: 746 CGGAPCHGVTG--QCRCPPG-RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC 802
C C G +C CPPG R G D A C + C+E PA + RC+ G+
Sbjct: 893 CQSGICTNTDGSFECICPPGHRAGPDL-ASCLDVD---ECRERGPALCGSQRCENSPGSY 948
Query: 803 LCL----PGFVG---SRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHC--SCAPGW-- 851
C+ PG+ C DV YGP C N P + C +C PG+
Sbjct: 949 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENT----PGSYRCTPACDPGYQP 1004
Query: 852 -TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQGH 908
G CQ +C + C A H C + G CLC+ GY G R + C +
Sbjct: 1005 TPGGGCQDV-------DECRNRSFCGA-HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1056
Query: 909 FGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA 966
CE A C++V G+ C CP E P + R++ G+
Sbjct: 1057 ---ECETLQGVCGAALCENVEGSFLCVCP-----NSPEEFDPMTGRCVPPRTSAGTFPGS 1108
Query: 967 ACDAVNGSCL-----CPAGRRGPRCAETCPAHTYGHNC----SQACACFNGASCDPVHGQ 1017
A L P R P P + C + AC N + + +
Sbjct: 1109 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQE 1168
Query: 1018 CHC--APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE-K 1074
C C GW +Q CP + + LC +G G+ A P G L +
Sbjct: 1169 CCCTVGEGWGSGCRIQQCPG---TETAEYQSLCPHG------RGYLA-PSGDLSLRRDVD 1218
Query: 1075 EC-LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
EC L RD C+ SG C+N C C G+ + C+ + CA
Sbjct: 1219 ECQLFRD--QVCK-SGVCVN----TAPGYSCYCSNGYYYHTQRLECID---NDECADEEP 1268
Query: 1134 CPPGAACHHVTGA--CRCPPGFTGSGCEQAC 1162
G C + G+ C C P G ++ C
Sbjct: 1269 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1299
Score = 128 bits (321), Expect = 5e-29
Identities = 145/517 (28%), Positives = 187/517 (36%), Gaps = 120/517 (23%)
Query: 102 TEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCV--PGSAQPCHCPPGFQ-GPR 157
T+ C G+ P CL ECS G C GS + C CPPG + GP
Sbjct: 860 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE-CICPPGHRAGPD 918
Query: 158 CQ--YDVDECRTHNGGC--QHRCVNTPGSYLC--ECKPGFRLHTDSRTCLAINSCA-LGN 210
DVDECR RC N+PGSY C +C PG+ + TC ++ C G
Sbjct: 919 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGP 977
Query: 211 GGCQHHCVQLTITRHRCQ--CRPGFQLQEDGRHCVRRSPCANRNGSCMHR-CQVVRGLAR 267
C + T +RC C PG+Q G C C NR+ H CQ + G +
Sbjct: 978 EICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1036
Query: 268 CECHVGYQLAADGKACEDVDE-------CAAGLAQCAHG-----CLNTQGSF-----KCV 310
C C GY+ A DG+ C DV+E C A L + G C N+ F +CV
Sbjct: 1037 CLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1096
Query: 311 ---CHAGY---------------------------------ELGADGRQCYRIEMEIVNS 334
AG +G+ R+CY + ++
Sbjct: 1097 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY-FDTAAPDA 1155
Query: 335 CE---ANNGGCSHGCSHTSAG-------------------PLCTCPRGYELDT-DQRTCI 371
C+ A N C G LC RGY + D
Sbjct: 1156 CDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR 1215
Query: 372 DVDDCA---DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCE-HHC 427
DVD+C D C VC N GY C C GY C D DECA CE C
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1275
Query: 428 TNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQD 487
N GS+ C+CE L +R C E +D D L +Q
Sbjct: 1276 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD------------------DNLGVCWQ- 1316
Query: 488 DDVGADE--EEAELRGEHTLTEKFVCLDDSFGHDCSL 522
+VGAD L + T TE +++G DC+L
Sbjct: 1317 -EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCAL 1352
Score = 120 bits (301), Expect = 1e-26
Identities = 221/881 (25%), Positives = 281/881 (31%), Gaps = 245/881 (27%)
Query: 670 SCSCKAGFR----GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGE 725
+C+C +GFR G RC E P C G C + P F+
Sbjct: 532 TCACDSGFRLSPQGTRCIDVDECRRVPPPC--------------APGRC-ENSPGSFRCV 576
Query: 726 DCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEI 785
CG G C C P G+C PG C A G CQ++
Sbjct: 577 -CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV 635
Query: 786 CPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS-CAND------GHC 838
Q C GAC LPG RC VCPAG+ G +C+ CA + G C
Sbjct: 636 DECTQSPGLCG--RGACKNLPG--SFRC--VCPAGFRGSACEEDVDECAQEPPPCGPGRC 689
Query: 839 HPATG--HCSCAPGWT----GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL--CL 890
G HC+C G+ G CQ + P C++ G C+ G C+
Sbjct: 690 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY--------GRCENTEGSFQCV 741
Query: 891 CEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAG 950
C G+ +C CE C G C + G+ C CP+G
Sbjct: 742 CPMGFQPNTAGSECEDVD---ECENHLACP-GQECVNSPGSFQC----------RTCPSG 787
Query: 951 --FFGLDCRSACNCTAGAA-------CDAVNGSCLC--------PAGRRGPRCAETCPAH 993
C C++GA C GS C P+GR GP CA+
Sbjct: 788 HHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADV---- 842
Query: 994 TYGHNCSQACACFNGASCDPVHGQ--CHCAPGWM----GPSCLQACPAGLYGDNCRHSCL 1047
+ C + CF C G C CAPG+ G SCL D C L
Sbjct: 843 ---NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDV-------DECSEEDL 892
Query: 1048 CQNGGTCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGL-CD--PHTG 1102
CQ+G C G C CP G CL D CR G L G C+ P +
Sbjct: 893 CQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDE---CRERGPALCGSQRCENSPGSY 948
Query: 1103 RCL--CPAGWTG---------DKCQSPCLRGWFGEAC-AQRCSCPPGAACHHVTGACRCP 1150
RC+ C G+ D+CQ + E C AQRC PG+ + T AC
Sbjct: 949 RCVRDCDPGYHAGPEGTCDDVDECQE-----YGPEICGAQRCENTPGS--YRCTPAC--D 999
Query: 1151 PGFT---GSGCEQA--------------CP--PGSF-------------GEDCAQ----- 1173
PG+ G GC+ C PGSF G C
Sbjct: 1000 PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1059
Query: 1174 ------------------MCQCPGENPACHPATGTC----SCAAGYHG--------PSCQ 1203
+C CP P TG C + A + G P
Sbjct: 1060 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1119
Query: 1204 QRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG 1263
R PP P + G + C T C+ + C G
Sbjct: 1120 ARPPP----PPLPRRPSTPRQGPVGSGRRECYFDTA-APDACDNILARNVTWQECCCTVG 1174
Query: 1264 CGQGAACD----PVTGTC----LCPPGRAGVRCERGCPQNRFGVGCE--HTCSCRNGGLC 1313
G G+ C P T T LCP GR + R C+ C++G
Sbjct: 1175 EGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCV 1234
Query: 1314 HASNG-SCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC---EPAT--GTCRCGP 1367
+ + G SC C G+ Y LEC +N C EPA G C
Sbjct: 1235 NTAPGYSCYCSNGY-------------YYHTQRLECI--DNDECADEEPACEGGRCVNTV 1279
Query: 1368 GFYGQACEHPCPPGFHGAGC-----------QGLCWCQHGA 1397
G Y CE P C G+CW + GA
Sbjct: 1280 GSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGA 1320
Score = 110 bits (276), Expect = 8e-24
Identities = 195/733 (26%), Positives = 235/733 (32%), Gaps = 132/733 (18%)
Query: 836 GHCHPATGHCSCAPGWTGFSCQRACDTGH---WGPDCSHPCN-CSAGHGSCDAISGLCLC 891
G+C CA G Q C G WG H C CS G+ + +S
Sbjct: 250 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGV---HDCQLCSERLGNSERVSAPD-- 304
Query: 892 EAGYVGPRCEQQCPQG--HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 949
GP CP G CE +C G C H G C G G C CP
Sbjct: 305 -----GP-----CPTGFERVNGSCEDVDECATGGRCQH--GECANTRG--GYTC--VCPD 348
Query: 950 GFFGLDCRSACNCT-----AGAACDAV--NGSCLCPAGRRGPR--CAETCPAHTYGHNCS 1000
GF RS+C A C V +G C P R + C + +G C
Sbjct: 349 GFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGC- 407
Query: 1001 QACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNG---GTCDPV 1057
Q C F + C PG+ + G L Q T P
Sbjct: 408 QLCPPFGSEGFREI---CPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPS 464
Query: 1058 SGHCAC----------PEGWAGLACEKECLPR----DVRAGCRHSGGCL-NGGLCDPHTG 1102
+G P+ G +P ++ SG C N +C P G
Sbjct: 465 AGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP--G 522
Query: 1103 RCLC-PAGWTGDKCQSPCLRGWFGEACAQRCSC---PPGAACHHVTGACRCPPGFTGSGC 1158
RC+ P+G+T C S G C C PP A G C PG C
Sbjct: 523 RCISRPSGYTC-ACDSGFRLSPQGTRCIDVDECRRVPPPCA----PGRCENSPGSFRCVC 577
Query: 1159 EQACPPGSFGEDCAQMCQCPGENPACH-------PATGTCSCAAGY----HGPSCQQRCP 1207
G +C + +C P C P + C C AGY HG SCQ
Sbjct: 578 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV-- 635
Query: 1208 PGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCG 1265
C Q G G+C G+ C CP GF G+ C + P CG
Sbjct: 636 -----DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPP-----PCG 685
Query: 1266 QGAACDPVTGT--CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG------GLCHASN 1317
G CD G+ C CP AG R RG G C+ C G C +
Sbjct: 686 PGR-CDNTAGSFHCACP---AGFR-SRGP-----GAPCQDVDECARSPPPCTYGRCENTE 735
Query: 1318 GSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHP 1377
GS C C + P G+ C C N+ C C PG + C
Sbjct: 736 GSFQCV-------CPMGFQPNTAGSECEDVDECENHLACPGQE--CVNSPGSF--QCR-T 783
Query: 1378 CPPG--FHGAGCQGLCWCQHGAP-CDPISGRCLCPAGFHGHFCERGCEPGSFGEG-CHQR 1433
CP G H C + C GAP C P G C G C G S G C
Sbjct: 784 CPSGHHLHRGRCTDVDECSSGAPPCGP-HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 842
Query: 1434 CDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCH 1493
+C G C P G CL G TC R G G SC +C C SG C
Sbjct: 843 NECLEGDFCFP-HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ--SGICT 899
Query: 1494 CVDGYMGPTCREG 1506
DG C G
Sbjct: 900 NTDGSFECICPPG 912
Score = 56.2 bits (134), Expect = 2e-07
Identities = 73/304 (24%), Positives = 100/304 (32%), Gaps = 62/304 (20%)
Query: 132 LCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGF 191
+C +GG CV C CPP F G CQ H+ G + PG
Sbjct: 119 ICHNGGVCV--KPDRCLCPPDFAGKFCQL-------HSSGARPPAPAVPGLTRSVYTMPL 169
Query: 192 RLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANR 251
H D +A H + ++ H+ + R +E V R+ A
Sbjct: 170 ANHRDDEHGVASMVSVH-----VEHPQEASVVVHQVE-RVSGPWEEADAEAVARAEAA-- 221
Query: 252 NGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLA---------QCAHGCLN 302
AR E Y + A ED A+G +CA
Sbjct: 222 --------------ARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPG 267
Query: 303 TQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH--GCSHTSAGPLCTCPRG 360
+ C AG G V+ C+ CS G S + P CP G
Sbjct: 268 LRTQEVCCRGAGLAWG-------------VHDCQL----CSERLGNSERVSAPDGPCPTG 310
Query: 361 YELDTDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 419
+E +C DVD+CA CQ C N GGY C C G+ L + C + +
Sbjct: 311 FERVNG--SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA 368
Query: 420 RGGC 423
+G C
Sbjct: 369 KGPC 372
Score = 54.7 bits (130), Expect = 7e-07
Identities = 49/137 (35%), Positives = 58/137 (42%), Gaps = 21/137 (15%)
Query: 105 RTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQ--GPRCQYDV 162
RT CCRG C CS L G SA CP GF+ C+ DV
Sbjct: 269 RTQEVCCRGAGLAWGVHDCQL--CSERL----GNSERVSAPDGPCPTGFERVNGSCE-DV 321
Query: 163 DECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCL-------AINSC--ALGNGG 212
DEC T G CQH C NT G Y C C GF L + +C+ A C L +GG
Sbjct: 322 DECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGG 380
Query: 213 CQHHCVQLTITRHRCQC 229
C ++ IT+ C C
Sbjct: 381 CSLPILR-NITKQICCC 396
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 156 PRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGG--- 212
P + + +EC +G RCV P + C C G+RL C+ IN C
Sbjct: 1491 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1550
Query: 213 CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCA 249
C + T RC CRPGF HC P A
Sbjct: 1551 CVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1587
Score = 53.9 bits (128), Expect = 1e-06
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 381 CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC----ASSRGGCEHHCTNLAGSFQC 436
C C P G+ C C+ GYRL C D++EC A+S C N GSF+C
Sbjct: 1506 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1565
Query: 437 SCEAGYRLHEDRRGCSP 453
C G+ C+P
Sbjct: 1566 ICRPGFAPTHQPHHCAP 1582
Score = 52.4 bits (124), Expect = 3e-06
Identities = 60/213 (28%), Positives = 78/213 (36%), Gaps = 46/213 (21%)
Query: 24 PAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQ---------PCVQALSHTVPVWK 74
PA PV + PP P LP +P P Q GRR+ C L+ V W+
Sbjct: 1113 PASPVLPARPPPPPLPRRPSTPR----QGPVGSGRRECYFDTAAPDACDNILARNV-TWQ 1167
Query: 75 AGC-----GWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCC---RGWMQQPDEEGCLSA 126
C GW + C +Q TE C RG++ P + L
Sbjct: 1168 ECCCTVGEGWGSGC-----------RIQQCPGTETAEYQSLCPHGRGYLA-PSGDLSLRR 1215
Query: 127 ECSASLCFHGGRCVPG------SAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQH-R 175
+ F C G C+C G+ Q C D DEC C+ R
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC-IDNDECADEEPACEGGR 1274
Query: 176 CVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL 208
CVNT GSY C C+P L R C++ S +L
Sbjct: 1275 CVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSL 1307
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 248 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC---AAGLAQCAHG-CLNT 303
C +G RC V C C GY+L AC D++EC A C + CLNT
Sbjct: 1500 CGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNT 1559
Query: 304 QGSFKCVCHAGY 315
GSF+C+C G+
Sbjct: 1560 DGSFRCICRPGF 1571
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 341 GCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC----ADSPCCQQV-CTNNPGGYE 394
GC++G C G C C GY LD + C+D+++C A SP C C N G +
Sbjct: 1505 GCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1564
Query: 395 CGCYAGY 401
C C G+
Sbjct: 1565 CICRPGF 1571
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 24/150 (16%)
Query: 285 DVDECAAGLAQ-CAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC 342
DVDEC Q C G C+NT + C C GY +C + C C
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND-----ECADEEPAC 1270
Query: 343 SHG-CSHTSAGPLCTCPRGYELDTDQRTCI-----DVDD----C-----ADSPCCQQVCT 387
G C +T CTC LD QR C+ +DD C AD C
Sbjct: 1271 EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLD 1330
Query: 388 NNPGGYECGCYAGYRLSADG--CGCEDVDE 415
EC C G D C +D D+
Sbjct: 1331 RQATYTECCCLYGEAWGMDCALCPAQDSDD 1360
Score = 33.9 bits (76), Expect = 1.3
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 14/69 (20%)
Query: 394 ECGCYAGY------RLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED 447
E G YAG L A+ CG +D C + R C + F C C GYRL
Sbjct: 1480 EGGSYAGSLAEPYEELEAEECGI--LDGCTNGR------CVRVPEGFTCRCFDGYRLDMT 1531
Query: 448 RRGCSPLEE 456
R C + E
Sbjct: 1532 RMACVDINE 1540
Score = 31.2 bits (69), Expect = 8.1
Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 5/79 (6%)
Query: 285 DVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS 343
+ +EC L C +G C+ F C C GY L C +++ + EA + C
Sbjct: 1496 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC--VDINECDEAEAASPLCV 1552
Query: 344 HG-CSHTSAGPLCTCPRGY 361
+ C +T C C G+
Sbjct: 1553 NARCLNTDGSFRCICRPGF 1571
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 233 bits (594), Expect = 1e-60
Identities = 252/922 (27%), Positives = 334/922 (36%), Gaps = 160/922 (17%)
Query: 120 EEGCLSAECSASLCFHG-GRCVPG-SAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQ 173
E G S C + G GRC+ S C C GF QG RC DVDECR C
Sbjct: 541 ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA 599
Query: 174 H-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232
RC N+PGS+ C C PGFR + CL ++ C C + T C C G
Sbjct: 600 PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAG 659
Query: 233 FQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACE-DVDECA 290
+Q G C C G C C+ + G RC C G++ G ACE DVDECA
Sbjct: 660 YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECA 715
Query: 291 AGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSH 348
C G C NT GSF C C AG+ G C + V+ C + C++G C +
Sbjct: 716 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC-----QDVDECARSPPPCTYGRCEN 770
Query: 349 TSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECG-CYAGYRLSAD 406
T C CP G++ +T C DVD+C + C Q C N+PG ++C C +G+ L
Sbjct: 771 TEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 830
Query: 407 GCGCEDVDECASSRGGC--EHHCTNLAGSFQCSCEAGYRLHEDRRG-CSPLEEPMVDLDG 463
C DVDEC+S C HCTN GSF+CSC GYR R G C+ + E L+G
Sbjct: 831 RC--TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNE---CLEG 885
Query: 464 ELPFVRPLPHIAVLQDE------LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFG 517
+ F PH L + ++ GA + + E L + +C +
Sbjct: 886 DFCF----PHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGS 941
Query: 518 HDC--------------SLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFG-- 561
+C L D+CR G L G C+ G C C P
Sbjct: 942 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG--SYRCVRDCDPGYHAGP 999
Query: 562 -KNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYG---------KHCRKKC 611
C CQ G + GA RC C C GY CR +
Sbjct: 1000 EGTCDDVDECQEYG--PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRS 1057
Query: 612 NCANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP--HTQSCDKR 667
C C L G+ CLCD G G C EC+ +Q C+
Sbjct: 1058 FCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD-------VNECETLQGVCGAALCENV 1110
Query: 668 DGS--CSCKAG------FRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCP 719
+GS C C G G F QA PV + +R
Sbjct: 1111 EGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPV-LPARPPPPPLPRRPS 1169
Query: 720 AGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
QG PVG+ C + A C + + T ++C EG WG
Sbjct: 1170 TPRQG-------PVGSGRRECYFDTAAPDA-CDNILAR-----NVTWQECCCTVGEG-WG 1215
Query: 780 LGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCP--AGWYGPSCQ-------TRC 830
GC+ +C PG + Q +CP G+ PS C
Sbjct: 1216 SGCR--------IQQC----------PGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1257
Query: 831 SCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHW----GPDCSHPCNCSAGHGSCDAIS 886
D C C G+SC C G++ +C C+ +C+
Sbjct: 1258 QLFRDQVCKSGV----CVNTAPGYSCY--CSNGYYYHTQRLECIDNDECADEEPACE--G 1309
Query: 887 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG--------- 937
G C+ G CE G ++RC + D G C G
Sbjct: 1310 GRCVNTVGSYHCTCEPPLVL----DGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPR 1365
Query: 938 --WRGTFCEHACPAG-FFGLDC 956
+ T+ E C G +G+DC
Sbjct: 1366 LDRQATYTECCCLYGEAWGMDC 1387
Score = 159 bits (403), Expect = 2e-38
Identities = 176/640 (27%), Positives = 232/640 (36%), Gaps = 107/640 (16%)
Query: 96 YRQVYTTEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCV--PGSAQPCHCPPG 152
Y + TE C G+ C EC L G CV PGS Q CP G
Sbjct: 765 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSG 824
Query: 153 --FQGPRCQYDVDECRTHNGGC--QHRCVNTPGSYLCECKPGFRLHTDSR-TCLAINSCA 207
RC DVDEC + C C NT GS+ C C PG+R + C +N C
Sbjct: 825 HHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECL 883
Query: 208 LGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR 267
G+ H T C C PG++ G C+ C+ + C G
Sbjct: 884 EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 943
Query: 268 CECHVGYQLAADGKACEDVDECAA-GLAQC-AHGCLNTQGSFKCV--CHAGYELGADGR- 322
C C G++ D +C DVDEC G A C + C N+ GS++CV C GY G +G
Sbjct: 944 CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 1003
Query: 323 ----QCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD 378
+C EI + N S+ C+ C GY+ T C DVD+C +
Sbjct: 1004 DDVDECQEYGPEICGAQRCENTPGSYRCTPA-------CDPGYQ-PTPGGGCQDVDECRN 1055
Query: 379 SPCC--QQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQ 435
C VC N PG ++C C GY + DG C DV+EC + +G C C N+ GSF
Sbjct: 1056 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1115
Query: 436 CSCEAGYRLHE----------DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLF 485
C C + G P +P LP P P + P
Sbjct: 1116 CVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL----PRRPSTP 1171
Query: 486 QDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDD--CRNGGTCLLGLDGCDCP 543
+ VG+ E C D+ D CD+ RN + C C
Sbjct: 1172 RQGPVGSGRRE--------------CYFDTAAPD---ACDNILARN-----VTWQECCCT 1209
Query: 544 --EGWTGLICNETCPPDTFGKNCSFSCSCQNG----------------GTC----DSVTG 581
EGW + CP + + C +G C D V
Sbjct: 1210 VGEGWGSGCRIQQCPGT---ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 1266
Query: 582 ACRCPPGVSGTNCEDGCPKGYYGKHCRKKC----NCAN-RGRCHRLYGACLCDPGLYGRF 636
+ C G +C C GYY R +C CA+ C G C+ G Y
Sbjct: 1267 SGVCVNTAPGYSCY--CSNGYYYHTQRLECIDNDECADEEPACEG--GRCVNTVGSY--- 1319
Query: 637 CHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG 676
H TC P G + +CV +QS D G C + G
Sbjct: 1320 -HCTCEPPLVLDG--SQRRCVSNESQSLDDNLGVCWQEVG 1356
Score = 152 bits (384), Expect = 2e-36
Identities = 293/1176 (24%), Positives = 381/1176 (32%), Gaps = 293/1176 (24%)
Query: 270 CHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIE 328
C G++ +CEDVDECA G +C HG C NT+G + CVC G+ L + C I
Sbjct: 344 CPTGFERV--NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSC--IS 398
Query: 329 MEIVNSCEA------NNGGCSHGCSHTSAGPLCTCPR-GYELDTDQRTCIDVDDCADSPC 381
+++ + +GGCS +C C R G + C S
Sbjct: 399 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF----GSEG 454
Query: 382 CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 441
+++C PG + Y G ++ + S+ + + F +
Sbjct: 455 FREICPAGPGYHYSASDLRYNTRPLG---QEPPRVSLSQPRTLPATSRPSAGFLPT---- 507
Query: 442 YRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHI-AVLQDELPQLFQDDDVGADEEEAELR 500
+RL E R P P +L PLP I A E+P+ G + ++
Sbjct: 508 HRL-EPRPEPRPDPRPGPEL--------PLPSIPAWTGPEIPE--SGPSSGMCQRNPQVC 556
Query: 501 GEHTLTEKFVCLDDSFGHDCSLTCDD---CRNGGTCLLGLDGCDCPEGWTGLICNETCPP 557
G C+ G+ C+ CD GT + +D C PP
Sbjct: 557 GPGR------CISRPSGYTCA--CDSGFRLSPQGTRCIDVDEC------------RRVPP 596
Query: 558 DTFGKNC-----SFSCSCQNG-------GTCDSVTGACRCPPGVSGTNCEDG-------C 598
C SF C C G C V R PP CE+ C
Sbjct: 597 PCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVC 656
Query: 599 PKGY----YGKHCRKKCNCA-NRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEE 653
P GY +G C+ C + G C R GAC PG + CP G C E+
Sbjct: 657 PAGYQAAPHGASCQDVDECTQSPGLCGR--GACKNLPGSF----RCVCPAGFRGSACEED 710
Query: 654 C-QCVQPHTQ----SCDKRDGS--CSCKAGFR----GERCQAECELGYFGPGCWQACTCP 702
+C Q CD GS C+C AGFR G CQ E P C
Sbjct: 711 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG---- 766
Query: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCR- 759
C++ G CP GFQ G EC C + +C G C G QCR
Sbjct: 767 ---RCENTEGSFQCVCPMGFQPNTAGSECEDVD---ECENHLACPGQECVNSPGSFQCRT 820
Query: 760 CPPG---RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQ 814
CP G G + D C P C C G+ C C PG+
Sbjct: 821 CPSGHHLHRGRCTDVD--------ECSSGAPPCGPHGHCTNTEGSFRCSCAPGY------ 866
Query: 815 DVCPAGWYGP-----SCQTRCSCANDGHCHPATGH--CSCAPGW----TGFSC------- 856
P+G GP C C G C G C+CAPG+ G SC
Sbjct: 867 -RAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS 925
Query: 857 -QRACDTG-HWGPDCSHPCNCSAGH------GSC----------DAISGLCLCEAGYVGP 898
+ C +G D S C C GH SC A+ G CE
Sbjct: 926 EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 985
Query: 899 RCEQQCPQG-HFGP--GCEQRCQCQHGAACDHVSGACTC---PAGWRGTFCEHACPAGFF 952
RC + C G H GP C+ +CQ + GA C P +R C AC G+
Sbjct: 986 RCVRDCDPGYHAGPEGTCDDVDECQEYG--PEICGAQRCENTPGSYR---CTPACDPGYQ 1040
Query: 953 GL---------DCRSACNCTAGAACDAVNGS--CLCPAGRRGPR----CAETCPAHTYGH 997
+CR+ C A A C + GS CLC G G R C + T
Sbjct: 1041 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1100
Query: 998 NCSQA----------CACFNG-ASCDPVHGQC--------------------HCAPGWMG 1026
C A C C N DP+ G+C P
Sbjct: 1101 VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPP 1160
Query: 1027 PSCLQACPA----GLYGDNCRHSCLCQNGG--TCDPVSGH--------CACPEGWAGLAC 1072
P L P+ G G R C CD + C EGW G C
Sbjct: 1161 PPPLPRRPSTPRQGPVGSG-RRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGC 1218
Query: 1073 EKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG-----DKCQSPCLRGWFGEA 1127
+ P A + LC PH L P+G D+CQ
Sbjct: 1219 RIQQCPGTETAEYQ--------SLC-PHGRGYLAPSGDLSLRRDVDECQ----------- 1258
Query: 1128 CAQRCSCPPGAACHHVTG-ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHP 1186
+ C G + G +C C G+ + +C +C E PAC
Sbjct: 1259 LFRDQVCKSGVCVNTAPGYSCYCSNGYYYH---------TQRLECIDNDECADEEPACE- 1308
Query: 1187 ATGTCSCAAG-YHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC 1245
G C G YH C C P G ++ C S D G C G
Sbjct: 1309 -GGRCVNTVGSYH---C--TCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVG-----A 1357
Query: 1246 NLTCPQGRFGPNCTHV-CGCGQGAACDPVTGTCLCP 1280
+L C R T+ C C G A LCP
Sbjct: 1358 DLVCSHPRLDRQATYTECCCLYGEAWG--MDCALCP 1391
Score = 152 bits (383), Expect = 3e-36
Identities = 263/1024 (25%), Positives = 331/1024 (32%), Gaps = 204/1024 (19%)
Query: 613 CANRGRCHRLYGACLCDPGLYGRFCHLTC----PPWAFGPGCSEECQCVQPHTQSCDKRD 668
C N G C + CLC P G+FC L PP PG + + P D
Sbjct: 157 CHNGGVCVKP-DRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTM-PLANHRDDEH 214
Query: 669 GSCSCKA-----------------GFRGERCQAECELGYFGPGCWQA-CTCPVGVACDSV 710
G S + G +A+ E +A P V S
Sbjct: 215 GVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSA 274
Query: 711 SGECGKRCPAGFQ---GEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGE 767
E G +GF E G EC G+ C G GV C+ R G
Sbjct: 275 PREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVH-DCQLCSERLGN 333
Query: 768 DCEADCPEGRWGLGCQEICPACQHAARCDP----ETGACLCLPGFVGSRCQDVCPAGWYG 823
P+G G + + +C+ C + G C G G C VCP G+
Sbjct: 334 SERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRG--GYTC--VCPDGFLL 389
Query: 824 PSCQTRCSCANDGHCHPATGHC-------SCA-PGWTGFSCQRACDT---GHWGPDCS-- 870
S +R SC + A G C C+ P + Q C + WG C
Sbjct: 390 DS--SRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLC 447
Query: 871 HPCN-------CSAGHGSCDAISGL--CLCEAGYVGPRCEQQ---------------CPQ 906
P C AG G + S L G PR P
Sbjct: 448 PPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPT 507
Query: 907 GHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA 966
P E R + G S PA W G + P+ G+ R+ C G
Sbjct: 508 HRLEPRPEPRPDPRPGPELPLPS----IPA-WTGPEIPESGPSS--GMCQRNPQVCGPGR 560
Query: 967 ACDAVNG-SCLCPAGRR----GPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCA 1021
+G +C C +G R G RC + C+ C N P +C C
Sbjct: 561 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCEN----SPGSFRCVCG 615
Query: 1022 PGW-MGPSCLQACPAGLYGDNCRHSCLCQNGGTCD--PVSGHCACPEGWAGLACEKECLP 1078
PG+ GP + L D C + G C+ P S C CP G+ C
Sbjct: 616 PGFRAGPRAAEC----LDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 671
Query: 1079 RDVRAGCRHSGGCLNGGLCD--PHTGRCLCPAGWTGDKCQS----------PCLRGWFGE 1126
D C S G G C P + RC+CPAG+ G C+ PC G
Sbjct: 672 VD---ECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDN 728
Query: 1127 ACAQ-RCSCP-------PGAACHHVTGACRCPPGFTGSGCEQ-------ACP----PGSF 1167
C+CP PGA C V R PP T CE CP P +
Sbjct: 729 TAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTA 788
Query: 1168 GEDCAQM--CQ----CPGENPACHPATGTC-SCAAGYH--------GPSCQQRCPPGRYG 1212
G +C + C+ CPG+ P + C +C +G+H C PP
Sbjct: 789 GSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPP---- 844
Query: 1213 PGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC 1270
C G C G+ C C G+ P GR GP C V C +G C
Sbjct: 845 --------CGPHGHCTNTEGSFRCSCAPGY-------RAPSGRPGP-CADVNECLEGDFC 888
Query: 1271 DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRH 1330
P G CL G C G G C C LC +G C+ T
Sbjct: 889 FP-HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC--QSGICTN----TDGS 941
Query: 1331 CELACPPGRYG----AACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAG 1386
E CPPG A+C C + C PG Y C C PG+H AG
Sbjct: 942 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY--RCVRDCDPGYH-AG 998
Query: 1387 CQGLC----WCQHGAPCDPISGRCLCPAGFHGHFCERGCEPG---SFGEG------CHQR 1433
+G C CQ P I G C + C C+PG + G G C R
Sbjct: 999 PEGTCDDVDECQEYGP--EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR 1056
Query: 1434 CDCDGGAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ 1491
C A C + G CLC G GA C TL C G A C+ V G
Sbjct: 1057 SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC--VDVNECETLQGVC-GAALCENVEGS 1113
Query: 1492 CHCV 1495
CV
Sbjct: 1114 FLCV 1117
Score = 151 bits (381), Expect = 5e-36
Identities = 295/1146 (25%), Positives = 370/1146 (32%), Gaps = 303/1146 (26%)
Query: 526 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC 585
D G C L G +C GL E C C+ G V C
Sbjct: 282 DASGFGYCFRELRGGECASPLPGLRTQEVC--------------CRGAGLAWGVHDCQLC 327
Query: 586 PPGVSGT---NCEDG-CPKGY--YGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL 639
+ + + DG CP G+ C CA GRC +G C G Y C
Sbjct: 328 SERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQ--HGECANTRGGYTCVC-- 383
Query: 640 TCPPWAFGPGCSEECQCVQPHTQSCDK-------RDGSCSCK--AGFRGERCQAECELGY 690
P F S C+ H S K RDG CS + C
Sbjct: 384 ---PDGFLLD-SSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKA 439
Query: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAG-----------FQGEDCGQECPVGTFG-- 737
+G GC Q C P G S + CPAG + GQE P +
Sbjct: 440 WGRGC-QLCP-PFG------SEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQP 491
Query: 738 --VNCSSSCSCGGAPCHGVTGQCR-CPPGRTGEDCE---------ADCPEGRWGLGCQEI 785
+ +S S G P H + + P R G + + PE G +
Sbjct: 492 RTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQR 551
Query: 786 CPACQHAARC--DPETGACLCLPGF----VGSRCQDVCPAGWYGPSCQTRCSCANDGHCH 839
P RC P C C GF G+RC DV P C C N
Sbjct: 552 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENS---- 606
Query: 840 PATGHCSCAPGWTGFSCQRAC---DTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAG 894
P + C C PG+ C D H P PC+ G C+ G LC+C AG
Sbjct: 607 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPP---PCDL----GRCENTPGSFLCVCPAG 659
Query: 895 YVGPRCEQQCPQGHFGPGCEQRCQCQHG------AACDHVSGA--CTCPAGWRGTFCEHA 946
Y Q P G C+ +C AC ++ G+ C CPAG+RG+ CE
Sbjct: 660 Y------QAAPH---GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 710
Query: 947 CPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAG--RRGP--------RCAETCPAHT 994
+C CD GS C CPAG RGP CA + P T
Sbjct: 711 VD------ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 764
Query: 995 YGH----NCSQACAC-------FNGASCDPVHGQCHCAPGWMGPSCL--------QACPA 1035
YG S C C G+ C+ V +C G C+ + CP+
Sbjct: 765 YGRCENTEGSFQCVCPMGFQPNTAGSECEDV-DECENHLACPGQECVNSPGSFQCRTCPS 823
Query: 1036 G--LYGDNCRHSCLCQNGG-TCDPVSGHCACPEGWAGLACEKECLPRDVRAG-CRHSGGC 1091
G L+ C C +G C P GHC EG +C R G C C
Sbjct: 824 GHHLHRGRCTDVDECSSGAPPCGP-HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC 882
Query: 1092 LNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPP 1151
L G C PH G CL G + AC C P
Sbjct: 883 LEGDFCFPH-GECLNTDG----------------------------------SFACTCAP 907
Query: 1152 GFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPG-R 1210
G+ PG G C + +C E C +G C+ G S + CPPG R
Sbjct: 908 GYR---------PGPRGASCLDVDEC-SEEDLCQ--SGICTNTDG----SFECICPPGHR 951
Query: 1211 YGPGCEQLCGCLNGGSC----DAATGACRCPTGFLGTDCNLTCPQG-RFGP--NCTHVCG 1263
GP L CL+ C A G+ RC C C G GP C V
Sbjct: 952 AGP---DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 1008
Query: 1264 CGQ-------GAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA- 1315
C + C+ G+ C P C+ G Q G GC+ CRN C A
Sbjct: 1009 CQEYGPEICGAQRCENTPGSYRCTPA-----CDPGY-QPTPGGGCQDVDECRNRSFCGAH 1062
Query: 1316 -------SNGSCSCGLGW----TGRHC----ELACPPGRYGAAC------HLECSCHNN- 1353
+ C C G+ GRHC E G GAA C C N+
Sbjct: 1063 AVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSP 1122
Query: 1354 STCEPATGTC---RCGPG-FYGQACEHPCPP--------------------GFHGAGCQG 1389
+P TG C R G F G + P P G G+G +
Sbjct: 1123 EEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-RR 1181
Query: 1390 LCWCQHGAP--CDPISGR------CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAP 1441
C+ AP CD I R C C G +G GC + C G
Sbjct: 1182 ECYFDTAAPDACDNILARNVTWQECCCTVG------------EGWGSGCRIQ-QCPGTET 1228
Query: 1442 CDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCD--CGGGADCDPVSG-QCHCVDGY 1498
+ + LCP GR + D + C L D C G + G C+C +GY
Sbjct: 1229 AEYQS---LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGY 1285
Query: 1499 MGPTCR 1504
T R
Sbjct: 1286 YYHTQR 1291
Score = 147 bits (370), Expect = 1e-34
Identities = 293/1171 (25%), Positives = 395/1171 (33%), Gaps = 235/1171 (20%)
Query: 118 PDEEGCLSAECSASLCFH---GGRC---VPGSAQPCHCPPGFQGPRCQYDVDECRTHNGG 171
P E+G A CF GG C +PG C G +D C G
Sbjct: 275 PREDGYSDAS-GFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGN 333
Query: 172 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP 231
+ V+ P C GF S C ++ CA G G CQH T + C C
Sbjct: 334 SER--VSAPDG---PCPTGFERVNGS--CEDVDECATG-GRCQHGECANTRGGYTCVCPD 385
Query: 232 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-A 290
GF L C+ + + G C +V+R C + + C V +
Sbjct: 386 GFLLDSSRSSCISQHVISEAKGPCF---RVLRD-GGCSLPILRNITKQICCCSRVGKAWG 441
Query: 291 AGLAQCAHGCLNTQGSFKCVCHAG-----------YELGADGRQCYRIEMEIVNSCEANN 339
G C ++G F+ +C AG Y G++ R+ + + A
Sbjct: 442 RGCQLCPP--FGSEG-FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPAT- 497
Query: 340 GGCSHGCSHTSAGPLCTC---PRGYELDTDQRTCIDV--------------DDCADSPCC 382
S SAG L T PR E D R ++ + S C
Sbjct: 498 -------SRPSAGFLPTHRLEPRP-EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMC 549
Query: 383 Q---QVC-----TNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGS 433
Q QVC + P GY C C +G+RLS G C DVDEC C C N GS
Sbjct: 550 QRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGS 609
Query: 434 FQCSCEAGYRLHEDRRGCSPLEE-----PMVDLDGELPFVRPLPHIAVLQDELPQLFQDD 488
F+C C G+R C ++E P DL G P + V P +Q
Sbjct: 610 FRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENT-PGSFLCV----CPAGYQAA 663
Query: 489 DVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG-TCLLGLDGCDCPEGWT 547
GA ++ + +C+ + C G L G C CP G+
Sbjct: 664 PHGASCQDVD--------------------ECTQSPGLCGRGACKNLPGSFRCVCPAGFR 703
Query: 548 GLICNETC------PPDTFGKNC-----SFSCSCQ-------NGGTCDSVTGACRCPPGV 589
G C E PP C SF C+C G C V R PP
Sbjct: 704 GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 763
Query: 590 SGTNCEDG-------CPKGYY----GKHCRKKCNCANRGRCHRLYGACLCDPGLYG-RFC 637
+ CE+ CP G+ G C C N C C+ PG + R C
Sbjct: 764 TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPG--QECVNSPGSFQCRTC 821
Query: 638 ----HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGERCQAECELGYF 691
HL CS PH C +GS CSC G+R G
Sbjct: 822 PSGHHLHRGRCTDVDECSSGAPPCGPHGH-CTNTEGSFRCSCAPGYRAPS-------GRP 873
Query: 692 GP-----GCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN-CSSSCS 745
GP C + C C + G C G++ G C V+ CS
Sbjct: 874 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC----LDVDECSEEDL 929
Query: 746 CGGAPCHGVTG--QCRCPPG-RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC 802
C C G +C CPPG R G D A C + C+E PA + RC+ G+
Sbjct: 930 CQSGICTNTDGSFECICPPGHRAGPDL-ASCLDVD---ECRERGPALCGSQRCENSPGSY 985
Query: 803 LCL----PGFVG---SRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHC--SCAPGW-- 851
C+ PG+ C DV YGP C N P + C +C PG+
Sbjct: 986 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENT----PGSYRCTPACDPGYQP 1041
Query: 852 -TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQGH 908
G CQ +C + C A H C + G CLC+ GY G R + C +
Sbjct: 1042 TPGGGCQDV-------DECRNRSFCGA-HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1093
Query: 909 FGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA 966
CE A C++V G+ C CP E P + R++ G+
Sbjct: 1094 ---ECETLQGVCGAALCENVEGSFLCVCP-----NSPEEFDPMTGRCVPPRTSAGTFPGS 1145
Query: 967 ACDAVNGSCL-----CPAGRRGPRCAETCPAHTYGHNC----SQACACFNGASCDPVHGQ 1017
A L P R P P + C + AC N + + +
Sbjct: 1146 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQE 1205
Query: 1018 CHC--APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE-K 1074
C C GW +Q CP + + LC +G G+ A P G L +
Sbjct: 1206 CCCTVGEGWGSGCRIQQCPG---TETAEYQSLCPHG------RGYLA-PSGDLSLRRDVD 1255
Query: 1075 EC-LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
EC L RD C+ SG C+N C C G+ + C+ + CA
Sbjct: 1256 ECQLFRD--QVCK-SGVCVN----TAPGYSCYCSNGYYYHTQRLECID---NDECADEEP 1305
Query: 1134 CPPGAACHHVTGA--CRCPPGFTGSGCEQAC 1162
G C + G+ C C P G ++ C
Sbjct: 1306 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1336
Score = 128 bits (321), Expect = 5e-29
Identities = 145/517 (28%), Positives = 187/517 (36%), Gaps = 120/517 (23%)
Query: 102 TEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCV--PGSAQPCHCPPGFQ-GPR 157
T+ C G+ P CL ECS G C GS + C CPPG + GP
Sbjct: 897 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE-CICPPGHRAGPD 955
Query: 158 CQ--YDVDECRTHNGGC--QHRCVNTPGSYLC--ECKPGFRLHTDSRTCLAINSCA-LGN 210
DVDECR RC N+PGSY C +C PG+ + TC ++ C G
Sbjct: 956 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGP 1014
Query: 211 GGCQHHCVQLTITRHRCQ--CRPGFQLQEDGRHCVRRSPCANRNGSCMHR-CQVVRGLAR 267
C + T +RC C PG+Q G C C NR+ H CQ + G +
Sbjct: 1015 EICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1073
Query: 268 CECHVGYQLAADGKACEDVDE-------CAAGLAQCAHG-----CLNTQGSF-----KCV 310
C C GY+ A DG+ C DV+E C A L + G C N+ F +CV
Sbjct: 1074 CLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1133
Query: 311 ---CHAGY---------------------------------ELGADGRQCYRIEMEIVNS 334
AG +G+ R+CY + ++
Sbjct: 1134 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY-FDTAAPDA 1192
Query: 335 CE---ANNGGCSHGCSHTSAG-------------------PLCTCPRGYELDT-DQRTCI 371
C+ A N C G LC RGY + D
Sbjct: 1193 CDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR 1252
Query: 372 DVDDCA---DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCE-HHC 427
DVD+C D C VC N GY C C GY C D DECA CE C
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1312
Query: 428 TNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQD 487
N GS+ C+CE L +R C E +D D L +Q
Sbjct: 1313 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD------------------DNLGVCWQ- 1353
Query: 488 DDVGADE--EEAELRGEHTLTEKFVCLDDSFGHDCSL 522
+VGAD L + T TE +++G DC+L
Sbjct: 1354 -EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCAL 1389
Score = 120 bits (301), Expect = 1e-26
Identities = 221/881 (25%), Positives = 281/881 (31%), Gaps = 245/881 (27%)
Query: 670 SCSCKAGFR----GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGE 725
+C+C +GFR G RC E P C G C + P F+
Sbjct: 569 TCACDSGFRLSPQGTRCIDVDECRRVPPPC--------------APGRC-ENSPGSFRCV 613
Query: 726 DCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEI 785
CG G C C P G+C PG C A G CQ++
Sbjct: 614 -CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV 672
Query: 786 CPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS-CAND------GHC 838
Q C GAC LPG RC VCPAG+ G +C+ CA + G C
Sbjct: 673 DECTQSPGLCG--RGACKNLPG--SFRC--VCPAGFRGSACEEDVDECAQEPPPCGPGRC 726
Query: 839 HPATG--HCSCAPGWT----GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL--CL 890
G HC+C G+ G CQ + P C++ G C+ G C+
Sbjct: 727 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY--------GRCENTEGSFQCV 778
Query: 891 CEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAG 950
C G+ +C CE C G C + G+ C CP+G
Sbjct: 779 CPMGFQPNTAGSECEDVD---ECENHLACP-GQECVNSPGSFQC----------RTCPSG 824
Query: 951 --FFGLDCRSACNCTAGAA-------CDAVNGSCLC--------PAGRRGPRCAETCPAH 993
C C++GA C GS C P+GR GP CA+
Sbjct: 825 HHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADV---- 879
Query: 994 TYGHNCSQACACFNGASCDPVHGQ--CHCAPGWM----GPSCLQACPAGLYGDNCRHSCL 1047
+ C + CF C G C CAPG+ G SCL D C L
Sbjct: 880 ---NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDV-------DECSEEDL 929
Query: 1048 CQNGGTCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGL-CD--PHTG 1102
CQ+G C G C CP G CL D CR G L G C+ P +
Sbjct: 930 CQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDE---CRERGPALCGSQRCENSPGSY 985
Query: 1103 RCL--CPAGWTG---------DKCQSPCLRGWFGEAC-AQRCSCPPGAACHHVTGACRCP 1150
RC+ C G+ D+CQ + E C AQRC PG+ + T AC
Sbjct: 986 RCVRDCDPGYHAGPEGTCDDVDECQE-----YGPEICGAQRCENTPGS--YRCTPAC--D 1036
Query: 1151 PGFT---GSGCEQA--------------CP--PGSF-------------GEDCAQ----- 1173
PG+ G GC+ C PGSF G C
Sbjct: 1037 PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1096
Query: 1174 ------------------MCQCPGENPACHPATGTC----SCAAGYHG--------PSCQ 1203
+C CP P TG C + A + G P
Sbjct: 1097 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1156
Query: 1204 QRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG 1263
R PP P + G + C T C+ + C G
Sbjct: 1157 ARPPP----PPLPRRPSTPRQGPVGSGRRECYFDTA-APDACDNILARNVTWQECCCTVG 1211
Query: 1264 CGQGAACD----PVTGTC----LCPPGRAGVRCERGCPQNRFGVGCE--HTCSCRNGGLC 1313
G G+ C P T T LCP GR + R C+ C++G
Sbjct: 1212 EGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCV 1271
Query: 1314 HASNG-SCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC---EPAT--GTCRCGP 1367
+ + G SC C G+ Y LEC +N C EPA G C
Sbjct: 1272 NTAPGYSCYCSNGY-------------YYHTQRLECI--DNDECADEEPACEGGRCVNTV 1316
Query: 1368 GFYGQACEHPCPPGFHGAGC-----------QGLCWCQHGA 1397
G Y CE P C G+CW + GA
Sbjct: 1317 GSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGA 1357
Score = 110 bits (276), Expect = 8e-24
Identities = 195/733 (26%), Positives = 235/733 (32%), Gaps = 132/733 (18%)
Query: 836 GHCHPATGHCSCAPGWTGFSCQRACDTGH---WGPDCSHPCN-CSAGHGSCDAISGLCLC 891
G+C CA G Q C G WG H C CS G+ + +S
Sbjct: 287 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGV---HDCQLCSERLGNSERVSAPD-- 341
Query: 892 EAGYVGPRCEQQCPQG--HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 949
GP CP G CE +C G C H G C G G C CP
Sbjct: 342 -----GP-----CPTGFERVNGSCEDVDECATGGRCQH--GECANTRG--GYTC--VCPD 385
Query: 950 GFFGLDCRSACNCT-----AGAACDAV--NGSCLCPAGRRGPR--CAETCPAHTYGHNCS 1000
GF RS+C A C V +G C P R + C + +G C
Sbjct: 386 GFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGC- 444
Query: 1001 QACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNG---GTCDPV 1057
Q C F + C PG+ + G L Q T P
Sbjct: 445 QLCPPFGSEGFREI---CPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPS 501
Query: 1058 SGHCAC----------PEGWAGLACEKECLPR----DVRAGCRHSGGCL-NGGLCDPHTG 1102
+G P+ G +P ++ SG C N +C P G
Sbjct: 502 AGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP--G 559
Query: 1103 RCLC-PAGWTGDKCQSPCLRGWFGEACAQRCSC---PPGAACHHVTGACRCPPGFTGSGC 1158
RC+ P+G+T C S G C C PP A G C PG C
Sbjct: 560 RCISRPSGYTC-ACDSGFRLSPQGTRCIDVDECRRVPPPCA----PGRCENSPGSFRCVC 614
Query: 1159 EQACPPGSFGEDCAQMCQCPGENPACH-------PATGTCSCAAGY----HGPSCQQRCP 1207
G +C + +C P C P + C C AGY HG SCQ
Sbjct: 615 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDV-- 672
Query: 1208 PGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCG 1265
C Q G G+C G+ C CP GF G+ C + P CG
Sbjct: 673 -----DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPP-----PCG 722
Query: 1266 QGAACDPVTGT--CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG------GLCHASN 1317
G CD G+ C CP AG R RG G C+ C G C +
Sbjct: 723 PGR-CDNTAGSFHCACP---AGFR-SRGP-----GAPCQDVDECARSPPPCTYGRCENTE 772
Query: 1318 GSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHP 1377
GS C C + P G+ C C N+ C C PG + C
Sbjct: 773 GSFQCV-------CPMGFQPNTAGSECEDVDECENHLACPGQE--CVNSPGSF--QCR-T 820
Query: 1378 CPPG--FHGAGCQGLCWCQHGAP-CDPISGRCLCPAGFHGHFCERGCEPGSFGEG-CHQR 1433
CP G H C + C GAP C P G C G C G S G C
Sbjct: 821 CPSGHHLHRGRCTDVDECSSGAPPCGP-HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 879
Query: 1434 CDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCH 1493
+C G C P G CL G TC R G G SC +C C SG C
Sbjct: 880 NECLEGDFCFP-HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ--SGICT 936
Query: 1494 CVDGYMGPTCREG 1506
DG C G
Sbjct: 937 NTDGSFECICPPG 949
Score = 60.5 bits (145), Expect = 1e-08
Identities = 100/450 (22%), Positives = 150/450 (33%), Gaps = 88/450 (19%)
Query: 12 RAVVLALVLLLLPAVPVGASVPPRPLLPLQ-PGMPHVCAEQELTL-----VGRRQPCVQA 65
R ++L L+L L A AS P P ++ PG+P A + RR C++A
Sbjct: 10 RPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQTSRRSRCIRA 69
Query: 66 LSHTVPVWKAGCGWQAWCVG----------HERRTVYYMGYRQVYTTEARTVLRCCR--- 112
C C+ R+ + ++ + EAR +L+ R
Sbjct: 70 FCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRPRG 129
Query: 113 ----GWMQQPDEEGCLSAECSAS---LCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDEC 165
G +++ + + + +C +GG CV C CPP F G CQ
Sbjct: 130 PGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCV--KPDRCLCPPDFAGKFCQL----- 182
Query: 166 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 225
H+ G + PG H D +A H + ++ H
Sbjct: 183 --HSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVH-----VEHPQEASVVVH 235
Query: 226 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 285
+ + R +E V R+ A AR E Y + A ED
Sbjct: 236 QVE-RVSGPWEEADAEAVARAEAA----------------ARAEAAAPYTVLAQSAPRED 278
Query: 286 VDECAAGLA---------QCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCE 336
A+G +CA + C AG G V+ C+
Sbjct: 279 GYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWG-------------VHDCQ 325
Query: 337 ANNGGCSH--GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQ-VCTNNPGGY 393
CS G S + P CP G+E +C DVD+CA CQ C N GGY
Sbjct: 326 L----CSERLGNSERVSAPDGPCPTGFERVNG--SCEDVDECATGGRCQHGECANTRGGY 379
Query: 394 ECGCYAGYRLSADGCGCEDVDECASSRGGC 423
C C G+ L + C + ++G C
Sbjct: 380 TCVCPDGFLLDSSRSSCISQHVISEAKGPC 409
Score = 54.7 bits (130), Expect = 7e-07
Identities = 49/137 (35%), Positives = 58/137 (42%), Gaps = 21/137 (15%)
Query: 105 RTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQ--GPRCQYDV 162
RT CCRG C CS L G SA CP GF+ C+ DV
Sbjct: 306 RTQEVCCRGAGLAWGVHDCQL--CSERL----GNSERVSAPDGPCPTGFERVNGSCE-DV 358
Query: 163 DECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCL-------AINSC--ALGNGG 212
DEC T G CQH C NT G Y C C GF L + +C+ A C L +GG
Sbjct: 359 DECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGG 417
Query: 213 CQHHCVQLTITRHRCQC 229
C ++ IT+ C C
Sbjct: 418 CSLPILR-NITKQICCC 433
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 156 PRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGG--- 212
P + + +EC +G RCV P + C C G+RL C+ IN C
Sbjct: 1528 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1587
Query: 213 CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCA 249
C + T RC CRPGF HC P A
Sbjct: 1588 CVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1624
Score = 53.9 bits (128), Expect = 1e-06
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 381 CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC----ASSRGGCEHHCTNLAGSFQC 436
C C P G+ C C+ GYRL C D++EC A+S C N GSF+C
Sbjct: 1543 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1602
Query: 437 SCEAGYRLHEDRRGCSP 453
C G+ C+P
Sbjct: 1603 ICRPGFAPTHQPHHCAP 1619
Score = 52.4 bits (124), Expect = 3e-06
Identities = 60/213 (28%), Positives = 78/213 (36%), Gaps = 46/213 (21%)
Query: 24 PAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQ---------PCVQALSHTVPVWK 74
PA PV + PP P LP +P P Q GRR+ C L+ V W+
Sbjct: 1150 PASPVLPARPPPPPLPRRPSTPR----QGPVGSGRRECYFDTAAPDACDNILARNV-TWQ 1204
Query: 75 AGC-----GWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCC---RGWMQQPDEEGCLSA 126
C GW + C +Q TE C RG++ P + L
Sbjct: 1205 ECCCTVGEGWGSGC-----------RIQQCPGTETAEYQSLCPHGRGYLA-PSGDLSLRR 1252
Query: 127 ECSASLCFHGGRCVPG------SAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQH-R 175
+ F C G C+C G+ Q C D DEC C+ R
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC-IDNDECADEEPACEGGR 1311
Query: 176 CVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL 208
CVNT GSY C C+P L R C++ S +L
Sbjct: 1312 CVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSL 1344
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 248 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC---AAGLAQCAHG-CLNT 303
C +G RC V C C GY+L AC D++EC A C + CLNT
Sbjct: 1537 CGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNT 1596
Query: 304 QGSFKCVCHAGY 315
GSF+C+C G+
Sbjct: 1597 DGSFRCICRPGF 1608
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 341 GCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC----ADSPCCQQV-CTNNPGGYE 394
GC++G C G C C GY LD + C+D+++C A SP C C N G +
Sbjct: 1542 GCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1601
Query: 395 CGCYAGY 401
C C G+
Sbjct: 1602 CICRPGF 1608
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 24/150 (16%)
Query: 285 DVDECAAGLAQ-CAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC 342
DVDEC Q C G C+NT + C C GY +C + C C
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND-----ECADEEPAC 1307
Query: 343 SHG-CSHTSAGPLCTCPRGYELDTDQRTCI-----DVDD----C-----ADSPCCQQVCT 387
G C +T CTC LD QR C+ +DD C AD C
Sbjct: 1308 EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLD 1367
Query: 388 NNPGGYECGCYAGYRLSADG--CGCEDVDE 415
EC C G D C +D D+
Sbjct: 1368 RQATYTECCCLYGEAWGMDCALCPAQDSDD 1397
Score = 33.9 bits (76), Expect = 1.3
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 14/69 (20%)
Query: 394 ECGCYAGY------RLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED 447
E G YAG L A+ CG +D C + R C + F C C GYRL
Sbjct: 1517 EGGSYAGSLAEPYEELEAEECGI--LDGCTNGR------CVRVPEGFTCRCFDGYRLDMT 1568
Query: 448 RRGCSPLEE 456
R C + E
Sbjct: 1569 RMACVDINE 1577
Score = 31.2 bits (69), Expect = 8.1
Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 5/79 (6%)
Query: 285 DVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS 343
+ +EC L C +G C+ F C C GY L C +++ + EA + C
Sbjct: 1533 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC--VDINECDEAEAASPLCV 1589
Query: 344 HG-CSHTSAGPLCTCPRGY 361
+ C +T C C G+
Sbjct: 1590 NARCLNTDGSFRCICRPGF 1608
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 232 bits (591), Expect = 2e-60
Identities = 204/702 (29%), Positives = 258/702 (36%), Gaps = 174/702 (24%)
Query: 724 GEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDC-------EADCPEG 776
G C +C G CS G CH +C P + G C CP G
Sbjct: 281 GGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAG 340
Query: 777 RWGLGC---QEICPA--CQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ---T 828
G C Q C CQH +C E G+ +C VC AG+ G +C+
Sbjct: 341 FGGPTCETAQSPCDTKECQHGGQCQVENGSAVC-----------VCQAGYTGAACEMDVD 389
Query: 829 RCS---CANDGHCHPATGH--CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCD 883
CS C N G C G+ C CA + G C+ H PD C G D
Sbjct: 390 DCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETG---DHPVPDACLSAPCHNGGTCVD 446
Query: 884 AISG-LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA-CTCPAGWRGT 941
A G +C C G++G C ++ P C+C++G C + C CP G+ G
Sbjct: 447 ADQGYVCECPEGFMGLDCRERVPDD---------CECRNGGRCLGANTTLCQCPLGFFGL 497
Query: 942 FCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPA-HTYGHNCS 1000
CE A + C C G C GS LC C H H+
Sbjct: 498 LCEFEITA----MPCNMNTQCPDGGYCMEHGGSYLC-----------VCHTDHNASHSLP 542
Query: 1001 QAC---ACFNGASCDPVHGQ---CHCAPGWMGPSCLQACPAGLYGDNCRHSCL---CQNG 1051
C CFNG SCD H C C G+ G C +A P H C C+NG
Sbjct: 543 SPCDSDPCFNGGSCD-AHDDSYTCECPRGFHGKHCEKARP---------HLCSSGPCRNG 592
Query: 1052 GTCDPVSG--HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCP 1107
GTC G HC+CP + G CE + SG C NGG C + G +C CP
Sbjct: 593 GTCKEAGGEYHCSCPYRFTGRHCEIG------KPDSCASGPCHNGGTCFHYIGKYKCDCP 646
Query: 1108 AGWTGDKCQ---SPCLR----------------------GWFGEACAQRCSCPPGAACHH 1142
G++G C+ SPC R G+ G C C P H
Sbjct: 647 PGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKH 706
Query: 1143 VT--------GAC---RCPPGFTGSGCE--QACPP-GSFGE--DCAQMCQCPGENPACH- 1185
T GA C G++ S + C P G + E C ++ +C + P H
Sbjct: 707 ATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQ-PCLHG 765
Query: 1186 ------PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCP 1237
A C C+ GY G C+ R P C NGGSC GA CRCP
Sbjct: 766 GSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP-------CRNGGSCRNLPGAYVCRCP 818
Query: 1238 TGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRF 1297
GF+G C P C G C+ G LC CP++ F
Sbjct: 819 AGFVGVHCETEVDACDSSP-------CQHGGRCESGGGAYLCV-----------CPESFF 860
Query: 1298 GVGCE------HTCSCRNGGLCHASNG--SCSCGLGWTGRHC 1331
G CE + C G C ASNG SC+C +G+TG C
Sbjct: 861 GYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 217 bits (553), Expect = 6e-56
Identities = 231/783 (29%), Positives = 283/783 (36%), Gaps = 172/783 (21%)
Query: 761 PPGRTGEDCEADCPE-----GRWGLGCQEICPACQHAARCDPETGACLCL-PGFVGSRCQ 814
P RT + E + GRW I A C T CL L P G +C
Sbjct: 229 PGSRTADMAEVETTTNVGVPGRWAF---RIDDAQVRVGGCGHTTSVCLALRPCLNGGKCI 285
Query: 815 DVCPAGWYGPSCQTRCSCANDGH-CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC 873
D C G PS C G CH C+ P CQ G C+H
Sbjct: 286 DDCVTG--NPSYTCSCLSGFTGRRCHLDVNECASQP------CQN-------GGTCTHGI 330
Query: 874 NCSAGHGSCDAISGLCLCEAGYVGPRCEQ-QCPQGHFGPGCEQRCQCQHGAAC--DHVSG 930
N S C C AG+ GP CE Q P C+ + +CQHG C ++ S
Sbjct: 331 N-----------SFRCQCPAGFGGPTCETAQSP-------CDTK-ECQHGGQCQVENGSA 371
Query: 931 ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC-DAV-NGSCLCPAGRRGPRCAE 988
C C AG+ G CE +D S C G +C D V N +CLC +G RC
Sbjct: 372 VCVCQAGYTGAACE-------MDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC-- 422
Query: 989 TCPAHTYGHNCSQACA---CFNGASC-DPVHGQ-CHCAPGWMGPSCLQACPAGLYGDNCR 1043
T H AC C NG +C D G C C G+MG C + P
Sbjct: 423 ----ETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP--------- 469
Query: 1044 HSCLCQNGGTCDPVSGH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG 1102
C C+NGG C + C CP G+ GL CE E C + C +GG C H G
Sbjct: 470 DDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMP----CNMNTQCPDGGYCMEHGG 525
Query: 1103 RCLCPAGW---TGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE 1159
LC SPC + C SC H + C CP GF G CE
Sbjct: 526 SYLCVCHTDHNASHSLPSPC----DSDPCFNGGSCD----AHDDSYTCECPRGFHGKHCE 577
Query: 1160 QACP------PGSFGEDCAQM-----CQCPGENPACHPATGTC-SCAAG--YHGPSC--- 1202
+A P P G C + C CP H G SCA+G ++G +C
Sbjct: 578 KARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHY 637
Query: 1203 ----QQRCPPGRYGPGCEQLCG------CLNGGSCDAATGA--CRCPTGFLGTDCN--LT 1248
+ CPPG G CE C+NGG+C+ C C G++G C +
Sbjct: 638 IGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD 697
Query: 1249 C-PQGRFGPNCTHVCGCGQGA----ACDPVTGTCLCPPGRAGVRCERGC---PQNRFGVG 1300
C P G GA ACD G L P R V G P +
Sbjct: 698 CGPPEEVKHATLRFNGTRLGAVALYACD--RGYSLSAPSRIRVCQPHGVWSEPPQCLEID 755
Query: 1301 CEHTCSCRNGGLCH--ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCE- 1357
+ C +GG C + C C G+ G HCEL R H C N +C
Sbjct: 756 ECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE----RDECRAH---PCRNGGSCRN 808
Query: 1358 -PATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGR--CLCPAGFHG 1414
P CRC GF G CE C CQHG C+ G C+CP F G
Sbjct: 809 LPGAYVCRCPAGFVGVHCETEVD------ACDSSP-CQHGGRCESGGGAYLCVCPESFFG 861
Query: 1415 HFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNL-----DCRRGQF 1469
+ CE +P F C R G CL G TC + DC + F
Sbjct: 862 YHCETVSDP-CFSSPCGGR-------------GYCLASNGSHSCTCKVGYTGEDCAKELF 907
Query: 1470 GPS 1472
P+
Sbjct: 908 PPT 910
Score = 197 bits (500), Expect = 9e-50
Identities = 211/767 (27%), Positives = 281/767 (36%), Gaps = 150/767 (19%)
Query: 317 LGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDC 376
+G GR +RI+ + GGC H S C+ + C
Sbjct: 245 VGVPGRWAFRID-----DAQVRVGGCGHTTS---------------------VCLALRPC 278
Query: 377 ADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLAGSFQ 435
+ C C Y C C +G+ G C DV+ECAS CT+ SF+
Sbjct: 279 LNGGKCIDDCVTGNPSYTCSCLSGF----TGRRCHLDVNECASQPCQNGGTCTHGINSFR 334
Query: 436 CSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEE 495
C C AG+ SP + G+ V + V Q + DV
Sbjct: 335 CQCPAGFGGPTCETAQSPCDTKECQHGGQCQ-VENGSAVCVCQAGYTGAACEMDVDDCSP 393
Query: 496 EAELRGEH--TLTEKFVCL---------DDSFGHDCSLTC--DDCRNGGTCLLGLDG--C 540
+ L G L + CL ++ H C C NGGTC+ G C
Sbjct: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
Query: 541 DCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC-DSVTGACRCPPGVSGTNCEDGCP 599
+CPEG+ GL C E P D C C+NGG C + T C+CP G G CE
Sbjct: 454 ECPEGFMGLDCRERVPDD---------CECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT 504
Query: 600 KGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP 659
C C + G C G+ LC CH P + C
Sbjct: 505 ----AMPCNMNTQCPDGGYCMEHGGSYLC-------VCHTDHNASHSLPSPCDSDPCF-- 551
Query: 660 HTQSCDKRDGS--CSCKAGFRGERCQ-AECELGYFGPGCWQACTCPVGVACDSVSGECGK 716
+ SCD D S C C GF G+ C+ A L GP C G C GE
Sbjct: 552 NGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGP-------CRNGGTCKEAGGEYHC 604
Query: 717 RCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGV-TGQCRCPPGRTGEDCE-ADCP 774
CP F G+ C +G S C GG H + +C CPPG +G CE A P
Sbjct: 605 SCPYRF----TGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP 660
Query: 775 EGRWGLGCQEICPACQHAARC-DPETG-ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSC 832
R C + C D +T C C G++G RCQ G P +
Sbjct: 661 CFR---------SPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCG--PPEEVKHATL 709
Query: 833 ANDGHCHPATGHCSCAPGW--TGFSCQRACDT-GHWG--PDC-------SHPCNCSAGHG 880
+G A +C G+ + S R C G W P C S PC G
Sbjct: 710 RFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPC---LHGG 766
Query: 881 SC-DAISG-LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA--CTCPA 936
SC D ++G LCLC GY G CE + + P C++G +C ++ GA C CPA
Sbjct: 767 SCQDRVAGYLCLCSTGYEGAHCELERDECRAHP-------CRNGGSCRNLPGAYVCRCPA 819
Query: 937 GWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
G+ G CE +D + C G C++ G+ LC CP +G
Sbjct: 820 GFVGVHCETE-------VDACDSSPCQHGGRCESGGGAYLC-----------VCPESFFG 861
Query: 997 HNCSQAC-ACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNC 1042
++C CF+ P G+ +C SC C G G++C
Sbjct: 862 YHCETVSDPCFS----SPCGGRGYCLASNGSHSC--TCKVGYTGEDC 902
Score = 188 bits (478), Expect = 3e-47
Identities = 185/619 (29%), Positives = 220/619 (35%), Gaps = 169/619 (27%)
Query: 996 GHNCSQACA---CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR---HSCL-- 1047
GH S A C NG C C G PS +C +G G C + C
Sbjct: 266 GHTTSVCLALRPCLNGGKCID-----DCVTG--NPSYTCSCLSGFTGRRCHLDVNECASQ 318
Query: 1048 -CQNGGTCDPV--SGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR- 1103
CQNGGTC S C CP G+ G CE P D + C +GG C G
Sbjct: 319 PCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKE-------CQHGGQCQVENGSA 371
Query: 1104 -CLCPAGWTGDKCQSPCLRGWFGEACAQRCS---CPPGAACHHVTG--ACRCPPGFTGSG 1157
C+C AG+TG C E CS C G +C + G C C F G
Sbjct: 372 VCVCQAGYTGAAC----------EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLR 421
Query: 1158 CEQACPPGSFGEDCAQMCQCPGENPACHPATG-TCSCAAGYHGPSCQQRCPPGRYGPGCE 1216
CE P D C G C C G+ G C++R P
Sbjct: 422 CETGDHPVP---DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD------- 471
Query: 1217 QLCGCLNGGSC-DAATGACRCPTGFLGTDC-----------NLTCPQGRF----GPNCTH 1260
C C NGG C A T C+CP GF G C N CP G + G +
Sbjct: 472 --CECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC 529
Query: 1261 VCG-----------------CGQGAACDPVTG--TCLCPPGRAGVRCERGCPQNRFGVGC 1301
VC C G +CD TC CP G G CE+ P
Sbjct: 530 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARP-------- 581
Query: 1302 EHTCS---CRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC 1356
H CS CRNGG C + G CSC +TGRHCE+ P CH N TC
Sbjct: 582 -HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCH------NGGTC 634
Query: 1357 EPATGT--CRCGPGFYGQACE---HPC--PPGFHGAGCQG-----LCWCQHG-------- 1396
G C C PGF G+ CE PC P +G C+ C CQ G
Sbjct: 635 FHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQA 694
Query: 1397 -APCDPISGRCLCPAGFHG--------HFCERG-----------CEP-GSFGEG------ 1429
C P F+G + C+RG C+P G + E
Sbjct: 695 EVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEI 754
Query: 1430 --CHQRCDCDGGAPCDPVTG-LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCD 1486
C + GG+ D V G LCLC G GA C L+ C H C G C
Sbjct: 755 DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE------RDECRAH-PCRNGGSCR 807
Query: 1487 PVSGQ--CHCVDGYMGPTC 1503
+ G C C G++G C
Sbjct: 808 NLPGAYVCRCPAGFVGVHC 826
Score = 187 bits (476), Expect = 5e-47
Identities = 212/728 (29%), Positives = 273/728 (37%), Gaps = 164/728 (22%)
Query: 517 GHDCS--LTCDDCRNGGTCLLG-LDG-----CDCPEGWTGLICNETCPPDTFGKNCSFSC 568
GH S L C NGG C+ + G C C G+TG C+ N S
Sbjct: 266 GHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCH-------LDVNECASQ 318
Query: 569 SCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA- 625
CQNGGTC + C+CP G G CE C K C + G+C G+
Sbjct: 319 PCQNGGTCTHGINSFRCQCPAGFGGPTCETA------QSPCDTK-ECQHGGQCQVENGSA 371
Query: 626 -CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQA 684
C+C G G C + + P C CV + +C C F+G RC+
Sbjct: 372 VCVCQAGYTGAACEMDVDDCSPDP-CLNGGSCVDL------VGNYTCLCAEPFKGLRCET 424
Query: 685 ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNC---- 740
PV AC S G C QG C ECP G G++C
Sbjct: 425 GDH--------------PVPDACLSAPCHNGGTCVDADQGYVC--ECPEGFMGLDCRERV 468
Query: 741 SSSCSC-GGAPCHGV-TGQCRCPPGRTGEDCE-----------ADCPEGRWGLGCQE--- 784
C C G C G T C+CP G G CE CP+G + C E
Sbjct: 469 PDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGY---CMEHGG 525
Query: 785 ----ICPACQHAARCDPETGACLCLPGFVGSRCQD-------VCPAGWYGPSCQTR---- 829
+C +A+ P C P F G C CP G++G C+
Sbjct: 526 SYLCVCHTDHNASHSLP--SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHL 583
Query: 830 CS---CANDGHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDA 884
CS C N G C A G HCSC +TG R C+ G S PC+ G+C
Sbjct: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFTG----RHCEIGKPDSCASGPCH---NGGTCFH 636
Query: 885 ISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACD--HVSGACTCPAGWRG 940
G C C G+ G CE P R C +G C+ C C AG+ G
Sbjct: 637 YIGKYKCDCPPGFSGRHCE-------IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG 689
Query: 941 TFCEHACPAG-----------FFG--LDCRSACNCTAGAACDAVNGSCLC-PAG--RRGP 984
C+ G F G L + C G + A + +C P G P
Sbjct: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPP 749
Query: 985 RCAETCPAHTYGHNCSQACACFNGASC-DPVHGQ-CHCAPGWMGPSCLQACPAGLYGDNC 1042
+C E SQ C +G SC D V G C C+ G+ G C L D C
Sbjct: 750 QCLEIDECR------SQPC--LHGGSCQDRVAGYLCLCSTGYEGAHC------ELERDEC 795
Query: 1043 RHSCLCQNGGTCDPVSGH--CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPH 1100
R + C+NGG+C + G C CP G+ G+ CE E D + C+H G C +GG
Sbjct: 796 R-AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACD-SSPCQHGGRCESGG----G 849
Query: 1101 TGRCLCPAGWTGDKCQS---PCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSG 1157
C+CP + G C++ PC F C R C H +C C G+TG
Sbjct: 850 AYLCVCPESFFGYHCETVSDPC----FSSPCGGRGYCLASNGSH----SCTCKVGYTGED 901
Query: 1158 C-EQACPP 1164
C ++ PP
Sbjct: 902 CAKELFPP 909
Score = 179 bits (455), Expect = 1e-44
Identities = 191/693 (27%), Positives = 250/693 (36%), Gaps = 149/693 (21%)
Query: 639 LTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQA 698
L P G C ++C P +CSC +GF G RC + P C
Sbjct: 273 LALRPCLNGGKCIDDCVTGNPSY--------TCSCLSGFTGRRCHLDVNECASQP-CQNG 323
Query: 699 CTCPVGVACDSVSGECGKRCPAGFQGEDC-GQECPVGTFGVNCSSSCSCGGAPCHGVTGQ 757
TC G+ S C +CPAGF G C + P T C GG C G
Sbjct: 324 GTCTHGIN----SFRC--QCPAGFGGPTCETAQSPCDT------KECQHGG-QCQVENGS 370
Query: 758 --CRCPPGRTGEDCEADCPE----------------GRWGLGCQEICPACQHAARCDPET 799
C C G TG CE D + G + C E + P
Sbjct: 371 AVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVP 430
Query: 800 GACLCLPGFVGSRCQDV-------CPAGWYGPSCQTR----CSCANDGHCHPA-TGHCSC 847
ACL P G C D CP G+ G C+ R C C N G C A T C C
Sbjct: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQC 490
Query: 848 APGWTGFSCQ-----RACDTGHWGPD---C-----SHPCNCSAGHGSCDAISGLCLCEAG 894
G+ G C+ C+ PD C S+ C C H + ++ C +
Sbjct: 491 PLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC 550
Query: 895 YVGPRCEQ-------QCPQGHFGPGCEQR----CQ---CQHGAACDHVSGA--CTCPAGW 938
+ G C+ +CP+G G CE+ C C++G C G C+CP +
Sbjct: 551 FNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRF 610
Query: 939 RGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNG--SCLCPAGRRGPRCAETCPAHTYG 996
G CE P D ++ C G C G C CP G G C E P+ +
Sbjct: 611 TGRHCEIGKP------DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHC-EIAPSPCF- 662
Query: 997 HNCSQACACFNGASCDPVHGQ--CHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC 1054
C NG +C+ CHC G+MG C G + +H+ L NG
Sbjct: 663 -----RSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCG-PPEEVKHATLRFNGTRL 716
Query: 1055 DPVSGHCACPEGWAGLACE--KECLPRDVRA---------GCRHSGGCLNGGLCDPHTG- 1102
V+ + AC G++ A + C P V + CR S CL+GG C
Sbjct: 717 GAVALY-ACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECR-SQPCLHGGSCQDRVAG 774
Query: 1103 -RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCE 1159
CLC G+ G C+ + C C G +C ++ GA CRCP GF G CE
Sbjct: 775 YLCLCSTGYEGAHCELE------RDECRAH-PCRNGGSCRNLPGAYVCRCPAGFVGVHCE 827
Query: 1160 ---QACPPGSFGEDCAQMCQCPGENPACHPATGT--CSCAAGYHGPSCQQRCPPGRYGPG 1214
AC + CQ G C G C C + G C+ P P
Sbjct: 828 TEVDACD--------SSPCQHGGR---CESGGGAYLCVCPESFFGYHCETVSDPCFSSP- 875
Query: 1215 CEQLCGCLNGGSCDAATG--ACRCPTGFLGTDC 1245
C G C A+ G +C C G+ G DC
Sbjct: 876 ------CGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 174 bits (441), Expect = 6e-43
Identities = 153/477 (32%), Positives = 182/477 (38%), Gaps = 103/477 (21%)
Query: 1084 GCRHSGG-------CLNGGLC--DPHTGR----CLCPAGWTGDKCQSPCLRGWFGEACAQ 1130
GC H+ CLNGG C D TG C C +G+TG +C CA
Sbjct: 264 GCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDV------NECAS 317
Query: 1131 RCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPAT 1188
+ C G C H + C+CP GF G CE A P E C QC EN +
Sbjct: 318 Q-PCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKE-CQHGGQCQVEN-----GS 370
Query: 1189 GTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG--ACRCPTGFLGTDCN 1246
C C AGY G +C+ P CLNGGSC G C C F G
Sbjct: 371 AVCVCQAGYTGAACEMDVDDCSPDP-------CLNGGSCVDLVGNYTCLCAEPFKG---- 419
Query: 1247 LTCPQGRFG-PNCTHVCGCGQGAAC-DPVTG-TCLCPPGRAGVRCERGCPQNRFGVGCEH 1303
L C G P+ C G C D G C CP G G+ C P +
Sbjct: 420 LRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD-------- 471
Query: 1304 TCSCRNGGLCHASNGS-CSCGLGWTGRHCELA-----------CPPGRY---GAACHLEC 1348
C CRNGG C +N + C C LG+ G CE CP G Y +L C
Sbjct: 472 -CECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYL-C 529
Query: 1349 SCH-NNSTCEPATGTCRCGPGFYGQACEH-------PCPPGFHGAGCQG----LCW---C 1393
CH +++ C P F G +C+ CP GFHG C+ LC C
Sbjct: 530 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPC 589
Query: 1394 QHGAPCDPISGR--CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGL--C 1449
++G C G C CP F G CE G +P S G C G C G C
Sbjct: 590 RNGGTCKEAGGEYHCSCPYRFTGRHCEIG-KPDSCASG-----PCHNGGTCFHYIGKYKC 643
Query: 1450 LCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ--CHCVDGYMGPTCR 1504
CPPG SG C + PS C G C+ CHC GYMG C+
Sbjct: 644 DCPPGFSGRHCEI-------APSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ 693
Score = 167 bits (422), Expect = 9e-41
Identities = 193/714 (27%), Positives = 252/714 (35%), Gaps = 166/714 (23%)
Query: 133 CFHGGRCVP-----GSAQPCHCPPGFQGPRCQYDVDECRT---HNGGCQHRCVNTPGSYL 184
C +GG+C+ + C C GF G RC DV+EC + NGG C + S+
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG---TCTHGINSFR 334
Query: 185 CECKPGFRLHT--------DSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF--- 233
C+C GF T D++ C C + NG C C+ G+
Sbjct: 335 CQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAV------------CVCQAGYTGA 382
Query: 234 QLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDE---CA 290
+ D C PC N GSC+ + G C C ++ G CE D A
Sbjct: 383 ACEMDVDDC-SPDPCLN-GGSCVD----LVGNYTCLCAEPFK----GLRCETGDHPVPDA 432
Query: 291 AGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSH 348
A C +G C++ + C C G+ +G D R+ + + CE NGG G +
Sbjct: 433 CLSAPCHNGGTCVDADQGYVCECPEGF-MGLDCRE------RVPDDCECRNGGRCLGANT 485
Query: 349 TSAGPLCTCPRGY-----ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRL 403
T LC CP G+ E + C C D C + + G Y C C+ +
Sbjct: 486 T----LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCME----HGGSYLCVCHTDHNA 537
Query: 404 SADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDG 463
S D D C + G C+ H S+ C C G+
Sbjct: 538 SHSLPSPCDSDPCFNG-GSCDAH----DDSYTCECPRGF--------------------- 571
Query: 464 ELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEH--TLTEKFVCLDDSFGHDCS 521
H + P L E GE+ + +F G S
Sbjct: 572 ---------HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDS 622
Query: 522 LTCDDCRNGGTCL--LGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCD-- 577
C NGGTC +G CDCP G++G C P F C NGGTC+
Sbjct: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP-------CFRSPCVNGGTCEDR 675
Query: 578 SVTGACRCPPGVSGTNC--EDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPG--LY 633
C C G G C E C KH + N G LY CD G L
Sbjct: 676 DTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAV-ALYA---CDRGYSLS 731
Query: 634 GRFCHLTCPP---WAFGPGCSEECQC-VQP--HTQSCDKRDGS--CSCKAGFRGERCQAE 685
C P W+ P C E +C QP H SC R C C G+ G C+ E
Sbjct: 732 APSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE 791
Query: 686 --------CELGYFG---PGCWQACTCPVGV----------ACDSVSGECGKRCPAGFQG 724
C G PG + C CP G ACDS + G RC +G
Sbjct: 792 RDECRAHPCRNGGSCRNLPGAY-VCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGA 850
Query: 725 EDCGQECPVGTFGVNCSS-SCSCGGAPCHG--------VTGQCRCPPGRTGEDC 769
C CP FG +C + S C +PC G + C C G TGEDC
Sbjct: 851 YLC--VCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 144 bits (363), Expect = 7e-34
Identities = 172/665 (25%), Positives = 238/665 (35%), Gaps = 179/665 (26%)
Query: 127 ECSASLCFHGGRCVPG-SAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH--RCVNTPGSY 183
EC++ C +GG C G ++ C CP GF GP C+ C T CQH +C GS
Sbjct: 314 ECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKE--CQHGGQCQVENGSA 371
Query: 184 LCECKPGFRLHTDSRTCLAINSCALG---NGGCQHHCVQLTITRHRCQCRPGFQ--LQED 238
+C C+ G+ T + + ++ C+ NGG CV L + + C C F+ E
Sbjct: 372 VCVCQAGY---TGAACEMDVDDCSPDPCLNGG---SCVDL-VGNYTCLCAEPFKGLRCET 424
Query: 239 GRHCV----RRSPCANRNGSCM-----HRCQVVRGLA----------RCECHVGYQ-LAA 278
G H V +PC N G+C+ + C+ G CEC G + L A
Sbjct: 425 GDHPVPDACLSAPCHN-GGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGA 483
Query: 279 DGKACEDVDECAAGL-----------------AQCAHG--CLNTQGSFKCVCHAGYELG- 318
+ C +C G QC G C+ GS+ CVCH +
Sbjct: 484 NTTLC----QCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH 539
Query: 319 -----ADGRQCYRIEMEIVNSCEANNGGC-SHGCSHTSAGPLCTCPRGYELDTDQRTCID 372
D C+ N G C +H S+T C CPRG+ ++
Sbjct: 540 SLPSPCDSDPCF------------NGGSCDAHDDSYT-----CECPRGFHGKHCEKARPH 582
Query: 373 VDDCADSPCCQ-QVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH--HCTN 429
+ C+ PC C G Y C C YR + C D CAS G C + C +
Sbjct: 583 L--CSSGPCRNGGTCKEAGGEYHCSC--PYRFTGRHCEIGKPDSCAS--GPCHNGGTCFH 636
Query: 430 LAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLF---- 485
G ++C C G+ R C P F P + +D F
Sbjct: 637 YIGKYKCDCPPGF----SGRHCEIAPSPC--------FRSPCVNGGTCEDRDTDFFCHCQ 684
Query: 486 ---------QDDDVGADEE--EAELRGEHTLTEKFVCLDDSFGHDCS------------- 521
+ D G EE A LR T G+ S
Sbjct: 685 AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGV 744
Query: 522 -------LTCDDCR-----NGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFS 567
L D+CR +GG+C + G C C G+ G C ++ +
Sbjct: 745 WSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE-------LERDECRA 797
Query: 568 CSCQNGGTCDSVTGA--CRCPPGVSGTNCE---DGCPKGYYGKHCRKKCNCANRGRCHRL 622
C+NGG+C ++ GA CRCP G G +CE D C C + GRC
Sbjct: 798 HPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSS----------PCQHGGRCESG 847
Query: 623 YGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE 680
GA C+C +G C P F C C+ SC+CK G+ GE
Sbjct: 848 GGAYLCVCPESFFGYHCETVSDP-CFSSPCGGRGYCL------ASNGSHSCTCKVGYTGE 900
Query: 681 RCQAE 685
C E
Sbjct: 901 DCAKE 905
Score = 119 bits (298), Expect = 2e-26
Identities = 112/362 (30%), Positives = 144/362 (39%), Gaps = 86/362 (23%)
Query: 124 LSAECSASLCFHGGRC-VPGSAQPCHCPPGFQGPRCQYDVDECRTH---NGGCQH--RCV 177
L + C + CF+GG C + C CP GF G C ++ R H +G C++ C
Sbjct: 541 LPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC----EKARPHLCSSGPCRNGGTCK 596
Query: 178 NTPGSYLCECKPGFRLHTDSRTCL--AINSCALG---NGG-CQHHCVQLTITRHRCQCRP 231
G Y C C F R C +SCA G NGG C H+ I +++C C P
Sbjct: 597 EAGGEYHCSCPYRF----TGRHCEIGKPDSCASGPCHNGGTCFHY-----IGKYKCDCPP 647
Query: 232 GFQLQEDGRHC------VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 285
GF GRHC RSPC N G+C R C C GY G+ C+
Sbjct: 648 GF----SGRHCEIAPSPCFRSPCVN-GGTCEDRDTDF----FCHCQAGYM----GRRCQA 694
Query: 286 VDECAAGLAQCAHGCLNTQGS-----FKCVCHAGYELGADGR--------------QCYR 326
+C + H L G+ C GY L A R QC
Sbjct: 695 EVDCGPP-EEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLE 753
Query: 327 IEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ- 383
I+ E + C HG C AG LC C GYE ++ D+C PC
Sbjct: 754 ID-------ECRSQPCLHGGSCQDRVAGYLCLCSTGYE---GAHCELERDECRAHPCRNG 803
Query: 384 QVCTNNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEH--HCTNLAGSFQCSCEA 440
C N PG Y C C AG+ G CE +VD C SS C+H C + G++ C C
Sbjct: 804 GSCRNLPGAYVCRCPAGF----VGVHCETEVDACDSS--PCQHGGRCESGGGAYLCVCPE 857
Query: 441 GY 442
+
Sbjct: 858 SF 859
Score = 108 bits (271), Expect = 3e-23
Identities = 107/384 (27%), Positives = 126/384 (32%), Gaps = 82/384 (21%)
Query: 1140 CHHVTGACRC-PPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYH 1198
C H T C P G C C G NP+ TCSC +G+
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTG---------------NPSY-----TCSCLSGFT 304
Query: 1199 GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGP 1256
G C P C NGG+C + C+CP GF G C P
Sbjct: 305 GRRCHLDVNECASQP-------CQNGGTCTHGINSFRCQCPAGFGGPTCETAQ-----SP 352
Query: 1257 NCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS---CRNGGLC 1313
T C G + + C+C G G CE CS C NGG C
Sbjct: 353 CDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDD----------CSPDPCLNGGSC 402
Query: 1314 H--ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG 1371
N +C C + G CE P AC L CHN TC A G
Sbjct: 403 VDLVGNYTCLCAEPFKGLRCETGDHP--VPDAC-LSAPCHNGGTCVDAD---------QG 450
Query: 1372 QACEHPCPPGFHGAGCQGL----CWCQHGAPC-DPISGRCLCPAGFHGHFCERGCEPGSF 1426
CE CP GF G C+ C C++G C + C CP GF G CE
Sbjct: 451 YVCE--CPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT---- 504
Query: 1427 GEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCD 1486
C+ C G C G LC C+ D PS C G CD
Sbjct: 505 AMPCNMNTQCPDGGYCMEHGGSYLC-------VCHTDHNASHSLPSPCDSDPCFNGGSCD 557
Query: 1487 PV--SGQCHCVDGYMGPTCREGGP 1508
S C C G+ G C + P
Sbjct: 558 AHDDSYTCECPRGFHGKHCEKARP 581
Score = 102 bits (254), Expect = 3e-21
Identities = 132/497 (26%), Positives = 171/497 (34%), Gaps = 104/497 (20%)
Query: 121 EGCLSAECSASL-----CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTH-NGGCQH 174
EG + +C + C +GGRC+ + C CP GF G C++++ + N C
Sbjct: 457 EGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPD 516
Query: 175 R--CVNTPGSYLCECKPGFRLHTDSRTCLAINS-C----ALGNGGCQHHCVQLTITRHRC 227
C+ GSYLC C HTD ++ S C G C H T C
Sbjct: 517 GGYCMEHGGSYLCVC------HTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYT-----C 565
Query: 228 QCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCECHVGYQLAADGKACE- 284
+C GF G+HC + P +G C + C+ G C C + G+ CE
Sbjct: 566 ECPRGFH----GKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFT----GRHCEI 617
Query: 285 -DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS 343
D CA+G C + G +KC C G+ GR C S N G C
Sbjct: 618 GKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS----GRHCEIAPSPCFRSPCVNGGTCE 673
Query: 344 HGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECG------C 397
C C GY R C DC P + T G G C
Sbjct: 674 D----RDTDFFCHCQAGYM----GRRCQAEVDCGP-PEEVKHATLRFNGTRLGAVALYAC 724
Query: 398 YAGYRLSADG----CG----------CEDVDECASSRGGCEH--HCTNLAGSFQCSCEAG 441
GY LSA C C ++DEC S C H C + + C C G
Sbjct: 725 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP--CLHGGSCQDRVAGYLCLCSTG 782
Query: 442 Y------------RLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAV-LQDELPQLFQDD 488
Y R H R G S +L G P + V + E+ D
Sbjct: 783 YEGAHCELERDECRAHPCRNGGS-----CRNLPGAYVCRCPAGFVGVHCETEVDAC--DS 835
Query: 489 DVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNG-----GTCLL--GLDGCD 541
E G L VC + FG+ C D C + G CL G C
Sbjct: 836 SPCQHGGRCESGGGAYLC---VCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCT 892
Query: 542 CPEGWTGLIC-NETCPP 557
C G+TG C E PP
Sbjct: 893 CKVGYTGEDCAKELFPP 909
Score = 86.7 bits (213), Expect = 2e-16
Identities = 86/267 (32%), Positives = 99/267 (37%), Gaps = 70/267 (26%)
Query: 1274 TGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS-------CRNGGLCHAS------NGSC 1320
T T + PGR R + Q R G GC HT S C NGG C + +C
Sbjct: 241 TTTNVGVPGRWAFRIDDA--QVRVG-GCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTC 297
Query: 1321 SCGLGWTGRHCELACPPGRYGAACHLECS---CHNNSTCEPATGTCRCGPGFYGQACEHP 1377
SC G+TGR C L EC+ C N TC + RC
Sbjct: 298 SCLSGFTGRRCHLDVN----------ECASQPCQNGGTCTHGINSFRC-----------Q 336
Query: 1378 CPPGFHGAGC---QGLC---WCQHGAPCDPISGR--CLCPAGFHGHFCERG---CEPGSF 1426
CP GF G C Q C CQHG C +G C+C AG+ G CE C P
Sbjct: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDP- 395
Query: 1427 GEGCHQRCDCDGGAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFG-PSCTLHCDCGGGA 1483
C G C + G CLC G L C G P L C G
Sbjct: 396 ---------CLNGGSCVDLVGNYTCLCAEPFKG----LRCETGDHPVPDACLSAPCHNGG 442
Query: 1484 DC-DPVSGQ-CHCVDGYMGPTCREGGP 1508
C D G C C +G+MG CRE P
Sbjct: 443 TCVDADQGYVCECPEGFMGLDCRERVP 469
Score = 77.0 bits (188), Expect = 1e-13
Identities = 61/192 (31%), Positives = 76/192 (39%), Gaps = 39/192 (20%)
Query: 100 YTTEARTVLRCCRG---WMQQPDEEGCLSA-ECSASLCFHGGRCVPGSA-QPCHCPPGFQ 154
Y+ A + +R C+ W + P CL EC + C HGG C A C C G++
Sbjct: 728 YSLSAPSRIRVCQPHGVWSEPPQ---CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 784
Query: 155 GPRCQYDVDECRTH---NGGCQHRCVNTPGSYLCECKPGF-RLH-------TDSRTCLAI 203
G C+ + DECR H NGG C N PG+Y+C C GF +H DS C
Sbjct: 785 GAHCELERDECRAHPCRNGG---SCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHG 841
Query: 204 NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRS-PCANRNGSCMHRCQVV 262
C G G + C C F G HC S PC + C
Sbjct: 842 GRCESGGGA------------YLCVCPESF----FGYHCETVSDPCFSSPCGGRGYCLAS 885
Query: 263 RGLARCECHVGY 274
G C C VGY
Sbjct: 886 NGSHSCTCKVGY 897
Score = 44.7 bits (104), Expect = 7e-04
Identities = 19/39 (48%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 122 GCLSAECSASLCFHGGRCVPGS-AQPCHCPPGFQGPRCQ 159
G + CS + C +GG CVPG+ A C C PGF+G RC+
Sbjct: 1305 GNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 40.8 bits (94), Expect = 0.010
Identities = 18/31 (58%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
Query: 1307 CRNGGLC--HASNGSCSCGLGWTGRHCELAC 1335
C+NGG C A SC CG G+ GR CELAC
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 38.1 bits (87), Expect = 0.066
Identities = 22/42 (52%), Positives = 23/42 (54%), Gaps = 7/42 (16%)
Query: 563 NCSFSCSCQNGGTCDSVTGA----CRCPPGVSGTNCEDGCPK 600
NCS + CQNGGTC V GA C C PG G CE C K
Sbjct: 1310 NCSEN-PCQNGGTC--VPGADAHSCDCGPGFKGRRCELACIK 1348
Score = 37.7 bits (86), Expect = 0.087
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 1347 ECSCHNNSTCEPATG--TCRCGPGFYGQACEHPC 1378
E C N TC P +C CGPGF G+ CE C
Sbjct: 1313 ENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 35.8 bits (81), Expect = 0.33
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 13/51 (25%)
Query: 1112 GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQAC 1162
G+ ++PC G +C PGA H +C C PGF G CE AC
Sbjct: 1309 GNCSENPCQNGG---------TCVPGADAH----SCDCGPGFKGRRCELAC 1346
Score = 35.8 bits (81), Expect = 0.33
Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 527 CRNGGTCLLGLD--GCDCPEGWTGLICNETC 555
C+NGGTC+ G D CDC G+ G C C
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 34.7 bits (78), Expect = 0.73
Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 2/32 (6%)
Query: 1048 CQNGGTCDP-VSGH-CACPEGWAGLACEKECL 1077
CQNGGTC P H C C G+ G CE C+
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACI 1347
Score = 32.3 bits (72), Expect = 3.6
Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 2/31 (6%)
Query: 832 CANDGHCHP-ATGH-CSCAPGWTGFSCQRAC 860
C N G C P A H C C PG+ G C+ AC
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 32.0 bits (71), Expect = 4.8
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 10/61 (16%)
Query: 1091 CLNGGLCDPHTGR--CLCPAGWTGDKCQSPCLRGWFGEACAQRCS------CPPGAACHH 1142
C NGG C P C C G+ G +C+ C++ C + S G CHH
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIK--VSRPCTRLFSETKAFPVWEGGVCHH 1373
Query: 1143 V 1143
V
Sbjct: 1374 V 1374
Score = 31.6 bits (70), Expect = 6.2
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 5/39 (12%)
Query: 998 NCSQACACFNGASCDP---VHGQCHCAPGWMGPSCLQAC 1033
NCS+ C NG +C P H C C PG+ G C AC
Sbjct: 1310 NCSEN-PCQNGGTCVPGADAHS-CDCGPGFKGRRCELAC 1346
Score = 31.6 bits (70), Expect = 6.2
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 1221 CLNGGSC--DAATGACRCPTGFLGTDCNLTC 1249
C NGG+C A +C C GF G C L C
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 226 bits (576), Expect = 1e-58
Identities = 225/776 (28%), Positives = 316/776 (40%), Gaps = 140/776 (18%)
Query: 127 EC--SASLCFHGGRCVPGSAQ-PCHCPPGFQG-PRCQY--DVDECRTHN-GGCQHRCVNT 179
EC + ++C HG CVPG CHC PG++ P+ +Y DV+EC G + C+NT
Sbjct: 577 ECRLNQNICGHG-ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNT 635
Query: 180 PGSYLCECKPGFRLHTDS--RTCLAINSCA----LGNGGCQHHCVQLTITRHRCQCRPGF 233
GSY C C G+RLH + R+C+ +N CA G+GG C+ ++C C PG+
Sbjct: 636 GGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGG---FCINFP-GHYKCNCYPGY 691
Query: 234 QLQ-------EDGRHCVRRSPCANRNGSCMHRCQVVRGLARC-ECHVGYQLAADGKACED 285
+L+ ED C R P + +G C ++ G +C C GY+ + G AC D
Sbjct: 692 RLKASRPPVCEDIDEC--RDPSSCPDGKCENK----PGSFKCIACQPGYR-SQGGGACRD 744
Query: 286 VDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 344
V+ECA G + C+ G C N GSF+C C GY DGR C V+ CEA + C +
Sbjct: 745 VNECAEG-SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD-----VDECEAGD-VCDN 797
Query: 345 G-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGY 401
G CS+T C C GY L D+ C D+D+C D P C C N G Y C C G+
Sbjct: 798 GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCINTNGSYRCLCPQGH 856
Query: 402 RLSADGCGCEDVDECASSRGGCEHH--CTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMV 459
RL G C+D+DEC+ C H C NL GS+ C C+ G+ +D+ GC +E+P
Sbjct: 857 RL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHH 915
Query: 460 DLDGELPFVRPLPHIAVLQDELPQLFQDDDVGA---DEEEAELRGEHTLTEKFVCLDDSF 516
+ L F + +VL + Q +GA D E ++ E D
Sbjct: 916 KKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGK 975
Query: 517 GH------------------DCSLTCDDCRNGGTCLLGLDG--CDCPEGW----TGLICN 552
G+ +C L + G C+ G C C +G+ L C
Sbjct: 976 GYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECV 1035
Query: 553 ETCPPDTFGKNCSFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGC--PKGYYGKHCR 608
+ C +C+N G C++ G C C P + + C P+ C+
Sbjct: 1036 DV-------DECLDESNCRN-GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQ 1087
Query: 609 KKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRD 668
C GRC L G+ C+ C PPW GP +CQ + + +R
Sbjct: 1088 DPAAC-RPGRCVNLPGSYRCE-------CR---PPWVPGPS-GRDCQLPESPAERAPERR 1135
Query: 669 GSCSCKAGFRGERCQAECELGYFGPG-CWQACTCPVGVACDSVSGEC-----GKRCPAGF 722
C + G G C GP + C C G + C G CP
Sbjct: 1136 DVCWSQRGEDG-----MCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTS- 1189
Query: 723 QGED----------CGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPGRTGEDCE 770
Q E G+ S C C C G C CP G +
Sbjct: 1190 QSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASR 1249
Query: 771 ADCPE-------GRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVC 817
A C + + GL C+ + RC +G+ C+C GF SR C
Sbjct: 1250 ARCVDIDECRELNQRGLLCK--------SERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 205 bits (522), Expect = 2e-52
Identities = 206/735 (28%), Positives = 284/735 (38%), Gaps = 121/735 (16%)
Query: 161 DVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 219
+ DECR + C H CV P Y C C PG+R H R C+ +N C G
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 220 LTITRHRCQCRPGFQLQ--EDGRHCVRRSPCANRN-----GSCMHRCQVVRGLARCECHV 272
T + C C G++L GR CV + CA + G C++ G +C C+
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCIN----FPGHYKCNCYP 689
Query: 273 GYQLAADGK-ACEDVDECAAGLAQCAHG-CLNTQGSFKCV-CHAGYELGADGRQCYRIEM 329
GY+L A CED+DEC + C G C N GSFKC+ C GY G
Sbjct: 690 GYRLKASRPPVCEDIDECRDP-SSCPDGKCENKPGSFKCIACQPGYRSQGGGA------C 742
Query: 330 EIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC-ADSPCCQQVCT 387
VN C A CS G C + CTC +GY D R+C+DVD+C A C +C+
Sbjct: 743 RDVNEC-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICS 801
Query: 388 NNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED 447
N PG ++C C +GY LS D CED+DEC C N GS++C C G+RL
Sbjct: 802 NTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGG 861
Query: 448 RRGCSPLEEPMVDLDGELPFVRPLPHIAV--LQDELPQLFQDDDVGADEEEA--ELRGEH 503
R+ C ++E D LPH A LQ + + ++ E+ H
Sbjct: 862 RK-CQDIDECSQDPS------LCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH 914
Query: 504 TLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGL---DGCD---CPEGWTGLICNETCPP 557
E ++ DD+ D L + + C LG D C+ CP ++ + CP
Sbjct: 915 HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPV-YSSAEFHSLCPD 973
Query: 558 DTFGKNCSFSCSCQNGG--------TC----DSVTGACRCPPGVSGTNCEDGCPKGYYGK 605
GK + + N G C + +C G C C +G+Y
Sbjct: 974 ---GKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECY--CKQGFYYD 1028
Query: 606 HCRKKC----NCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHT 661
+C C + C G C G Y C PP + P + QC+ P
Sbjct: 1029 GNLLECVDVDECLDESNCRN--GVCENTRGGYRCAC---TPPAEYSPA---QRQCLSPEE 1080
Query: 662 QSCDKRDGSCSCKAGFRGERC-------QAECELGYFGPGCWQACTCPVGVA-------- 706
D+ +C+ G RC + EC + + C P A
Sbjct: 1081 MDVDECQDPAACRPG----RCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRD 1136
Query: 707 -CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCR-CPPGR 764
C S GE G C G P TF C C G G QCR CPP
Sbjct: 1137 VCWSQRGEDG-MCAGPLAG-------PALTFDDCC---CRQG----RGWGAQCRPCPPRG 1181
Query: 765 TGEDCEADCPEGR--W-------GLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQD 815
G C E W G ++ + + + C +G C+ PG G+ C+
Sbjct: 1182 AGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPG--GAVCE- 1238
Query: 816 VCPAGWYGPSCQTRC 830
CP G+ + + RC
Sbjct: 1239 -CPGGFQLDASRARC 1252
Score = 114 bits (286), Expect = 6e-25
Identities = 117/423 (27%), Positives = 153/423 (36%), Gaps = 92/423 (21%)
Query: 110 CCRGWMQQPDEEGCLSA-ECSASLCFHGGRC--VPGSAQPCHCPPGFQGPR----CQYDV 162
C +G+ PD CL EC A G C PGS Q C C G+ R C+ D+
Sbjct: 770 CAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQ-CQCLSGYHLSRDRSHCE-DI 827
Query: 163 DECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCA------LGNGGC--- 213
DEC C+NT GSY C C G RL R C I+ C+ L +G C
Sbjct: 828 DECDFPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNL 886
Query: 214 -----------------QHHCVQLTITRHRCQCRPGFQ-------------LQED----- 238
QH C ++ H+ +C F Q++
Sbjct: 887 QGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSL 946
Query: 239 ----GRHCVRRSPCANRNGSCMHR-CQVVRGLARCECHVGYQLAADGKACEDVDECAA-G 292
G HC PC + + H C +G + V Y + A D+DEC G
Sbjct: 947 GAGWGDHC-EIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAH----RDIDECMLFG 1001
Query: 293 LAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA 351
C G C+NTQ ++C C G+ + +C ++ E ++ NG C +T
Sbjct: 1002 SEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVD-ECLDESNCRNG----VCENTRG 1056
Query: 352 GPLCTCPRGYELDTDQRTCI-----DVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSA 405
G C C E QR C+ DVD+C D C+ C N PG Y C C +
Sbjct: 1057 GYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGP 1116
Query: 406 DGCGC-----------EDVDECASSRGGCEHHCTNLAGSF----QCSCEAGYRLHEDRRG 450
G C E D C S RG LAG C C G R
Sbjct: 1117 SGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRP 1176
Query: 451 CSP 453
C P
Sbjct: 1177 CPP 1179
Score = 110 bits (276), Expect = 8e-24
Identities = 179/703 (25%), Positives = 230/703 (32%), Gaps = 187/703 (26%)
Query: 843 GHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN-------------CSAGHGSCDAISGL- 888
GH C PG +SC C+ G+ SHP + C G G C G
Sbjct: 586 GHGECVPGPPDYSCH--CNPGYR----SHPQHRYCVDVNECEAEPCGPGRGICMNTGGSY 639
Query: 889 -CLCEAGYVGPRCEQQCPQGHFGPG---------CEQRCQCQHGAACDHVSG--ACTCPA 936
C C GY + H G G C + C G C + G C C
Sbjct: 640 NCHCNRGY----------RLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYP 689
Query: 937 GWRGTFCEHACPAGFFGLD-CRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTY 995
G+R + + P +D CR +C G C+ GS C A + G R
Sbjct: 690 GYR---LKASRPPVCEDIDECRDPSSCPDGK-CENKPGSFKCIACQPGYRSQG------- 738
Query: 996 GHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCD 1055
G C C G+ C P G C PG +C Q G +C C+ G CD
Sbjct: 739 GGACRDVNECAEGSPCSP--GWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCD 796
Query: 1056 -------PVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLC 1106
P S C C G+ C D C C+ GG C G RCLC
Sbjct: 797 NGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDE---CDFPAACI-GGDCINTNGSYRCLC 852
Query: 1107 PAGWT---GDKCQSPCLRGWFGEACAQRCS-CPPGAACHHVTGA--CRCPPGFTGSGCEQ 1160
P G G KCQ + C+Q S C P AC ++ G+ C C GFT + +
Sbjct: 853 PQGHRLVGGRKCQDI-------DECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQH 905
Query: 1161 ACPPGSFGEDCAQMCQCPGENPACH-PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLC 1219
C E+ Q P C+ T C + QQ C C
Sbjct: 906 GC------EEVEQ----PHHKKECYLNFDDTVFCDSVLATNVTQQEC------------C 943
Query: 1220 GCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACD----PVTG 1275
L G D CP + + + CP G+ ++ G A D + G
Sbjct: 944 CSLGAGWGDHCE-IYPCPV-YSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFG 1001
Query: 1276 TCLCPPGRA-----GVRCERGCPQNRFGVG----------CEHTCSCRNGGLCHASNGSC 1320
+ +C G+ G C C Q + G C +CRNG +C + G
Sbjct: 1002 SEICKEGKCVNTQPGYECY--CKQGFYYDGNLLECVDVDECLDESNCRNG-VCENTRGGY 1058
Query: 1321 SCGLGWTGRHCELAC-PPGRYGAACHLEC---------SCHNNSTCEPATGTCRCGPGFY 1370
C AC PP Y A +C C + + C P G C PG Y
Sbjct: 1059 RC-----------ACTPPAEYSPA-QRQCLSPEEMDVDECQDPAACRP--GRCVNLPGSY 1104
Query: 1371 GQACEHPCPPGFHGAGCQ-------------GLCWCQHGAPCDPISGRCLCPAGFHGHFC 1417
C P PG G CQ +CW Q G G C P
Sbjct: 1105 RCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGE-----DGMCAGPL------- 1152
Query: 1418 ERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATC 1460
P + C R GA C P CPP +G+ C
Sbjct: 1153 ---AGPALTFDDCCCRQGRGWGAQCRP------CPPRGAGSHC 1186
Score = 103 bits (257), Expect = 1e-21
Identities = 84/323 (26%), Positives = 122/323 (37%), Gaps = 46/323 (14%)
Query: 161 DVDECRTHNGGC--QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCV 218
D+DEC + +CVNT Y C CK GF + C+ ++ C L C++
Sbjct: 993 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVC 1051
Query: 219 QLTITRHRCQCRPGFQLQEDGRHCVR---------RSPCANRNGSCMHRCQVVRGLARCE 269
+ T +RC C P + R C+ + P A R G C++ + G RCE
Sbjct: 1052 ENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVN----LPGSYRCE 1107
Query: 270 CHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSF---------------KCVCHAG 314
C + G+ C+ + A + C + +G C C G
Sbjct: 1108 CRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG 1167
Query: 315 YELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 374
GA R C + C + S S PL + D+ + D D
Sbjct: 1168 RGWGAQCRPCP--PRGAGSHCPTSQ---SESNSFWDTSPLLLGKPPRDEDSSEE---DSD 1219
Query: 375 DCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC--ASSRGGC--EHHCTNL 430
+C C C PGG C C G++L A C D+DEC + RG C N
Sbjct: 1220 ECR---CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNT 1276
Query: 431 AGSFQCSCEAGYRLHEDRRGCSP 453
+GSF+C C+AG+ C P
Sbjct: 1277 SGSFRCVCKAGFARSRPHGACVP 1299
Score = 99.4 bits (246), Expect = 2e-20
Identities = 191/819 (23%), Positives = 265/819 (32%), Gaps = 157/819 (19%)
Query: 578 SVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR---CHRLYGACLCDPGLYG 634
++ G C PG +C C GY + C N C G C+ G Y
Sbjct: 583 NICGHGECVPGPPDYSCH--CNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 640
Query: 635 RFCH--LTCPPWAFGPGCSEECQCVQPHTQS----CDKRDG--SCSCKAGFRGERCQAE- 685
C+ A G C + +C +PH C G C+C G+R + +
Sbjct: 641 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPV 700
Query: 686 CELGYFGPGCWQACTCPVGVACDSVSG--ECGKRCPAGFQGEDCGQECPVGTFGVNCSSS 743
CE C +CP G C++ G +C C G++ + G V C+
Sbjct: 701 CE---DIDECRDPSSCPDG-KCENKPGSFKC-IACQPGYRSQGGGACRDVN----ECAEG 751
Query: 744 CSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCD------- 796
C C + G RC T A P+GR L E C+ CD
Sbjct: 752 SPCSPGWCENLPGSFRC----TCAQGYAPAPDGRSCLDVDE----CEAGDVCDNGICSNT 803
Query: 797 PETGACLCLPGFVGSR----CQDVCPAGWYGPSCQTRCSCANDGHCHPATG--HCSCAPG 850
P + C CL G+ SR C+D+ C +C G C G C C G
Sbjct: 804 PGSFQCQCLSGYHLSRDRSHCEDI-------DECDFPAACIG-GDCINTNGSYRCLCPQG 855
Query: 851 WTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCP--- 905
++ D +CS + HG+C + G +C+C+ G+ + + C
Sbjct: 856 HRLVGGRKCQDID----ECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVE 911
Query: 906 QGHFGPGC----EQRCQCQHGAACDHVSGACTCP--AGWRGTFCE-HACPAGFFGLDCRS 958
Q H C + C A + C C AGW G CE + CP + + S
Sbjct: 912 QPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW-GDHCEIYPCPV-YSSAEFHS 969
Query: 959 ACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQC 1018
C G D + PA R C +G + C N P + +C
Sbjct: 970 LCPDGKGYTQDNNIVNYGIPAHRDIDECM------LFGSEICKEGKCVN---TQPGY-EC 1019
Query: 1019 HCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLP 1078
+C G+ L C + D C C+NG C+ G C
Sbjct: 1020 YCKQGFYYDGNLLEC---VDVDECLDESNCRNG-VCENTRGGYRC--------------- 1060
Query: 1079 RDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGA 1138
C P +CL P D+CQ P +C PG
Sbjct: 1061 -----------ACTPPAEYSPAQRQCLSPEEMDVDECQDPA-------------ACRPGR 1096
Query: 1139 ACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENP-----ACHPATGTCS- 1192
C ++ G+ RC C PG G DC Q+ + P E C G
Sbjct: 1097 -CVNLPGSYRCE-------CRPPWVPGPSGRDC-QLPESPAERAPERRDVCWSQRGEDGM 1147
Query: 1193 CAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNL-TCPQ 1251
CA GP+ R G G C C CPT ++ T P
Sbjct: 1148 CAGPLAGPALTFDDCCCRQGRGWGAQCR-----PCPPRGAGSHCPTSQSESNSFWDTSPL 1202
Query: 1252 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR--- 1308
P C V+G C+ PG A C G + C CR
Sbjct: 1203 LLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELN 1262
Query: 1309 -NGGLCHA-----SNGS--CSCGLGWTGRHCELACPPGR 1339
G LC + ++GS C C G+ AC P R
Sbjct: 1263 QRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1301
Score = 88.6 bits (218), Expect = 4e-17
Identities = 195/788 (24%), Positives = 247/788 (31%), Gaps = 183/788 (23%)
Query: 746 CGGAPCHGVTG----QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA 801
CG C V G C C PG P+ R+ + E C+ A C P G
Sbjct: 585 CGHGEC--VPGPPDYSCHCNPGYRSH------PQHRYCVDVNE----CE-AEPCGPGRGI 631
Query: 802 CLCLPGFVGSRCQDV--CPAGWYGPSCQ--TRCS----CANDGHCHPATGH--CSCAPGW 851
C+ G C G G SC C+ C + G C GH C+C PG+
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGY 691
Query: 852 T-GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG 910
S C+ +C P +C G C+ G C A G R + G
Sbjct: 692 RLKASRPPVCEDID---ECRDPSSCP--DGKCENKPGSFKCIACQPGYRSQG-------G 739
Query: 911 PGCEQRCQCQHGAACDHVSGAC-TCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACD 969
C +C G+ C G C P +R T + PA G C C AG CD
Sbjct: 740 GACRDVNECAEGSPCS--PGWCENLPGSFRCTCAQGYAPAPD-GRSCLDVDECEAGDVCD 796
Query: 970 AVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC 1029
NG C G +C +C C A+C + G C G C
Sbjct: 797 --NGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAAC--IGGDCINTNG--SYRC 850
Query: 1030 LQACPAG---LYGDNCRHSCLC-QNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGC 1085
L CP G + G C+ C Q+ C P G C +G C++ P + GC
Sbjct: 851 L--CPQGHRLVGGRKCQDIDECSQDPSLCLP-HGACKNLQGSYVCVCDEGFTPTQDQHGC 907
Query: 1086 R------HSGGCL----NGGLCDPHTG------RCLCP--AGWTGDKCQS-PCLRGWFGE 1126
H C + CD C C AGW GD C+ PC
Sbjct: 908 EEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW-GDHCEIYPCP---VYS 963
Query: 1127 ACAQRCSCPPGAA-------------CHHVTGACR------CPPGF---TGSGCEQACPP 1164
+ CP G H C C G T G E C
Sbjct: 964 SAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQ 1023
Query: 1165 GSFGE----DCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPG------ 1214
G + + +C + +C E+ G C G + +C PP Y P
Sbjct: 1024 GFYYDGNLLECVDVDECLDESNC---RNGVCENTRGGYRCACT---PPAEYSPAQRQCLS 1077
Query: 1215 --------CEQLCGCLNGGSCDAATGACRCPT------GFLGTDCNLTCPQGRFGPNCTH 1260
C+ C G C G+ RC G G DC L P
Sbjct: 1078 PEEMDVDECQDPAAC-RPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRD 1136
Query: 1261 VCGCGQGA---ACDPVTGT------CLCPPGRA-GVRCERGCPQNRFGVGCEHTCSCRNG 1310
VC +G P+ G C C GR G +C R CP G C + S N
Sbjct: 1137 VCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQC-RPCPPRGAGSHCPTSQSESNS 1195
Query: 1311 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY 1370
W L PP + S ++ C +G C PG
Sbjct: 1196 F--------------WDTSPLLLGKPPRDE------DSSEEDSDECRCVSGRCVPRPG-- 1233
Query: 1371 GQACEHPCPPGFH----GAGCQGLCWC----QHGAPCDPI-------SGRCLCPAGFHGH 1415
G CE CP GF A C + C Q G C S RC+C AGF
Sbjct: 1234 GAVCE--CPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARS 1291
Query: 1416 FCERGCEP 1423
C P
Sbjct: 1292 RPHGACVP 1299
Score = 76.6 bits (187), Expect = 2e-13
Identities = 72/253 (28%), Positives = 90/253 (35%), Gaps = 62/253 (24%)
Query: 119 DEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRC----QYDVDECRTHNGGCQH 174
DE C + C + + C P P P + +C + DVDEC+
Sbjct: 1042 DESNCRNGVCENTRGGYRCACTP----PAEYSPAQR--QCLSPEEMDVDECQDPAACRPG 1095
Query: 175 RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL--------------GNGGCQHHCVQL 220
RCVN PGSY CEC+P + R C S A +G C
Sbjct: 1096 RCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGP 1155
Query: 221 TITRHRCQCRPGFQLQEDGRHCVRR---SPCANRNGS----------------------- 254
+T C CR G R C R S C
Sbjct: 1156 ALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSE 1215
Query: 255 -------CMH-RCQVVRGLARCECHVGYQLAADGKACEDVDEC----AAGLAQCAHGCLN 302
C+ RC G A CEC G+QL A C D+DEC GL + C+N
Sbjct: 1216 EDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVN 1275
Query: 303 TQGSFKCVCHAGY 315
T GSF+CVC AG+
Sbjct: 1276 TSGSFRCVCKAGF 1288
Score = 67.8 bits (164), Expect = 8e-11
Identities = 92/339 (27%), Positives = 112/339 (33%), Gaps = 60/339 (17%)
Query: 1186 PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC 1245
P +C C GY P RY C + C C G C G C
Sbjct: 594 PPDYSCHCNPGYRSH------PQHRY---CVDVNEC-EAEPCGPGRGICMNTGGSYNCHC 643
Query: 1246 N--LTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERG--CPQNRFGVGC 1301
N G G +C + C + C G C+ PG C G +R V C
Sbjct: 644 NRGYRLHVGAGGRSCVDLNECAKPHLCGD-GGFCINFPGHYKCNCYPGYRLKASRPPV-C 701
Query: 1302 EHTCSCRN-----GGLCHASNGSCSCGLGWTGRHCELACPPG---RYGAACHLECSCHNN 1353
E CR+ G C GS C +AC PG + G AC C
Sbjct: 702 EDIDECRDPSSCPDGKCENKPGSFKC----------IACQPGYRSQGGGACRDVNECAEG 751
Query: 1354 STCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCD-------PISGRC 1406
S C P G C PG + C P G C + C+ G CD P S +C
Sbjct: 752 SPCSP--GWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQC 809
Query: 1407 LCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG--LCLCPPGR---SGATCN 1461
C +G+H CE + C C GG C G CLCP G G C
Sbjct: 810 QCLSGYHLSRDRSHCED---IDECDFPAACIGG-DCINTNGSYRCLCPQGHRLVGGRKCQ 865
Query: 1462 LDCRRGQFGPSCTLHCDCGGGADCDPVSGQ--CHCVDGY 1498
Q C H GA C + G C C +G+
Sbjct: 866 DIDECSQDPSLCLPH-----GA-CKNLQGSYVCVCDEGF 898
Score = 61.2 bits (147), Expect = 7e-09
Identities = 49/161 (30%), Positives = 65/161 (40%), Gaps = 23/161 (14%)
Query: 217 CVQLTITRHRCQCRP--GFQLQEDGRHCVRRSPCANRNGSCMHRCQV-----------VR 263
C Q T+ + C P G QED C A C H+C VR
Sbjct: 279 CFQDTLPKQPCGSNPLPGLTKQED---CCGSIGTAWGQSKC-HKCPQLQYTGVQKPGPVR 334
Query: 264 GLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGR 322
G +C GY+ + C+D++ECA C HG CLN GS++CVC G+ LG
Sbjct: 335 GEVGADCPQGYK-RLNSTHCQDINECAMP-GVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 323 QCYRIEMEIVNSC---EANNGGCSHGCSHTSAGPLCTCPRG 360
QC + E + C + C H + LC C G
Sbjct: 393 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG 433
Score = 47.4 bits (111), Expect = 1e-04
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 10/94 (10%)
Query: 357 CPRGYELDTDQRTCIDVDDCADSPCCQQV-CTNNPGGYECGCYAGYRLSADGCGC----- 410
CP+GY+ + C D+++CA C+ C NNPG Y C C G+ L C
Sbjct: 341 CPQGYKR-LNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKP 399
Query: 411 EDVDEC---ASSRGGCEHHCTNLAGSFQCSCEAG 441
E+ C S C+H T C C G
Sbjct: 400 EEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG 433
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 13/95 (13%)
Query: 149 CPPGFQ---GPRCQYDVDECRTHNGGCQHR-CVNTPGSYLCECKPGFRLHTDSRTCLA-- 202
CP G++ CQ D++EC G C+H C+N PGSY C C PG L C+A
Sbjct: 341 CPQGYKRLNSTHCQ-DINECAMP-GVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK 398
Query: 203 --INSCALGNGGCQHHC---VQLTITRHRCQCRPG 232
S +H C + +TR C C G
Sbjct: 399 PEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG 433
Score = 41.6 bits (96), Expect = 0.006
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 7/81 (8%)
Query: 376 CADSPCCQQVCTNNPGGYE----CGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNL 430
C P Q PG C GY+ + C+D++ECA G C H C N
Sbjct: 316 CHKCPQLQYTGVQKPGPVRGEVGADCPQGYK-RLNSTHCQDINECAMP-GVCRHGDCLNN 373
Query: 431 AGSFQCSCEAGYRLHEDRRGC 451
GS++C C G+ L R C
Sbjct: 374 PGSYRCVCPPGHSLGPSRTQC 394
Score = 39.7 bits (91), Expect = 0.023
Identities = 40/137 (29%), Positives = 59/137 (43%), Gaps = 17/137 (12%)
Query: 316 ELGADGRQCYR----IEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTC 370
E+GAD Q Y+ + +N C A G C HG C + C CP G+ L + C
Sbjct: 336 EVGADCPQGYKRLNSTHCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Query: 371 IDVDDCADSPCCQQVCTN--NPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCT 428
I AD P + +C +P ++C RL+ C C V + +R C+ T
Sbjct: 395 I-----ADKPEEKSLCFRLVSP-EHQCQHPLTTRLTRQLCCC-SVGKAWGAR--CQRCPT 445
Query: 429 NLAGSFQCSCEAGYRLH 445
+ +F+ C AG H
Sbjct: 446 DGTAAFKEICPAGKGYH 462
Score = 37.7 bits (86), Expect = 0.087
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 25/94 (26%)
Query: 1029 CLQACPAGLYGDNCRH----SCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAG 1084
C + C G D+C+ + + +NG + D ++G G+ + C LP
Sbjct: 71 CKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTG-----SGFRVVVCP---LP------ 116
Query: 1085 CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSP 1118
C+NGG C +CLCP +TG CQ P
Sbjct: 117 ------CMNGGQCSSRN-QCLCPPDFTGRFCQVP 143
Score = 35.4 bits (80), Expect = 0.43
Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 27/106 (25%)
Query: 1067 WAGLACEKECLPRDVRAGCRHSGGCL----NGGLCDPHTGRCLCPAGWTGDKCQSPCLRG 1122
+A + C++ CL R C+ NG D TG +G+ C PC+ G
Sbjct: 66 FAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTG-----SGFRVVVCPLPCMNG 120
Query: 1123 WFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFG 1168
C+ R C CPP FTG C+ P G G
Sbjct: 121 G---QCSSR-------------NQCLCPPDFTGRFCQ--VPAGGAG 148
Score = 34.3 bits (77), Expect = 0.96
Identities = 42/151 (27%), Positives = 59/151 (39%), Gaps = 28/151 (18%)
Query: 1056 PVSGHCA--CPEGWAGLA---CE--KECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPA 1108
PV G CP+G+ L C+ EC V CRH G CLN +P + RC+CP
Sbjct: 332 PVRGEVGADCPQGYKRLNSTHCQDINECAMPGV---CRH-GDCLN----NPGSYRCVCPP 383
Query: 1109 GWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFG 1168
G + ++ C+ + ++ C + H +C T Q C S G
Sbjct: 384 GHSLGPSRTQCI----ADKPEEKSLCFRLVSPEH-----QCQHPLTTRLTRQLC-CCSVG 433
Query: 1169 EDCAQMCQ-CPGENPACHPATGTCSCAAGYH 1198
+ CQ CP + A C GYH
Sbjct: 434 KAWGARCQRCPTDGTAAFKE--ICPAGKGYH 462
Score = 33.1 bits (74), Expect = 2.1
Identities = 59/198 (29%), Positives = 68/198 (34%), Gaps = 48/198 (24%)
Query: 714 CGKR-CPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEAD 772
CG P + EDC G+ G S C P TG + PG + AD
Sbjct: 289 CGSNPLPGLTKQEDC-----CGSIGTAWGQS-KCHKCPQLQYTGVQK--PGPVRGEVGAD 340
Query: 773 CPEGRWGLG---CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGW-YGPSCQT 828
CP+G L CQ+I C C G CL PG RC VCP G GPS
Sbjct: 341 CPQGYKRLNSTHCQDI-NECAMPGVC--RHGDCLNNPG--SYRC--VCPPGHSLGPS--- 390
Query: 829 RCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL 888
R C D + C R H C HP + L
Sbjct: 391 RTQCIADKPEEKSL-------------CFRLVSPEH---QCQHPL-------TTRLTRQL 427
Query: 889 CLCEAGYV-GPRCEQQCP 905
C C G G RC Q+CP
Sbjct: 428 CCCSVGKAWGARC-QRCP 444
Score = 32.0 bits (71), Expect = 4.8
Identities = 31/118 (26%), Positives = 39/118 (33%), Gaps = 15/118 (12%)
Query: 1280 PPGRAGVRCERGCPQNRFGVG-----CEHTC---SCRNGGLCHASNGSCSCGLGWTGRHC 1331
P G G + RF V C+ TC CR+ GS +G G
Sbjct: 45 PAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDS----CQQGSNMTLIGENGHST 100
Query: 1332 ELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQG 1389
+ G C L C N C + C C P F G+ C+ P G G G
Sbjct: 101 DTLTGSGFRVVVCPLPCM--NGGQCS-SRNQCLCPPDFTGRFCQVPAGGAGGGTGGSG 155
Score = 31.6 bits (70), Expect = 6.2
Identities = 15/39 (38%), Positives = 17/39 (43%), Gaps = 2/39 (5%)
Query: 133 CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGG 171
C +GG+C S C CPP F G CQ GG
Sbjct: 117 CMNGGQC--SSRNQCLCPPDFTGRFCQVPAGGAGGGTGG 153
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 223 bits (568), Expect = 1e-57
Identities = 198/638 (31%), Positives = 243/638 (38%), Gaps = 132/638 (20%)
Query: 928 VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA 987
+ G C C C+ P F L C N T G CD CP + P
Sbjct: 296 IGGRCVCHG--HADACDAKDPTDPFRLQCTCQHN-TCGGTCDRC-----CPGFNQQP--- 344
Query: 988 ETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL 1047
PA N Q+C C+ A+ C+ P Q+ G Y
Sbjct: 345 -WKPATANSANECQSCNCYGHAT------DCYYDPEVDRRRASQSLD-GTY--------- 387
Query: 1048 CQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAG---------CRHSG--GCLNGGL 1096
Q GG C C G+ CE+ CLP R+ CR G
Sbjct: 388 -QGGGVC------IDCQHHTTGVNCER-CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT 439
Query: 1097 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGS 1156
C+ TGRC C ++G++C C G+ G SC P P +
Sbjct: 440 CEDLTGRCYCRPNFSGERCDV-CAEGFTGFP-----SCYP-------------TPSSSND 480
Query: 1157 GCEQACPPGSFGEDCAQMCQCPG---ENPACH--PATGTCSCAAGYHGPSCQQRCPPGRY 1211
EQ P G C C + AC P G C C + G C+ C PG Y
Sbjct: 481 TREQVLPAGQIVN-----CDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFY 534
Query: 1212 GPGCEQLCGCLNGG----SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQG 1267
GPGC Q C C + G CD TG CRC GF G C+ C G F +CGC
Sbjct: 535 GPGC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCD-RCAPGYFHFPLCQLCGCSPA 592
Query: 1268 AA----CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG----LCHASNGS 1319
CD G CLC P AG C+R P C+ C+C G LC A G
Sbjct: 593 GTLPEGCDEA-GRCLCQPEFAGPHCDRCRPGYHGFPNCQ-ACTCDPRGALDQLCGAG-GL 649
Query: 1320 CSCGLGWTGRHCELACPPGRYG----AACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
C C G+TG C+ C PG +G CH ++ C+P +G C C P G C+
Sbjct: 650 CRCRPGYTGTACQ-ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCD 708
Query: 1376 HPCPPGFHGAGCQ-GLCWCQHGAPCDPISGR----CLCPAGFHGHFCERGCEPGSFG--- 1427
P ++ C+ G C AP DP C+C A G C+R C+PG +G
Sbjct: 709 TCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSP 767
Query: 1428 ---EGCHQRCDCD------GGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFG-------- 1470
EGC RC CD G A C P TG C C P G C C+ G FG
Sbjct: 768 SNPEGC-TRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFG 825
Query: 1471 -PSCTLHCDCGG--GADCDPVSGQCHCVDGYMGPTCRE 1505
SC CD GG G C+P +G C C GPTC E
Sbjct: 826 CRSC--RCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
Score = 201 bits (512), Expect = 3e-51
Identities = 183/616 (29%), Positives = 226/616 (36%), Gaps = 123/616 (19%)
Query: 916 RCQCQ-HGAACDHVSGA------CTCPAGWRGTFCEHACPAGF-----------FGLDCR 957
RC C H ACD CTC G C+ CP GF +C+
Sbjct: 299 RCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCP-GFNQQPWKPATANSANECQ 357
Query: 958 SACNCTAGAA-------CDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQA-------- 1002
S CNC A D S +G C HT G NC +
Sbjct: 358 S-CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSP 416
Query: 1003 ------------CAC---FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL 1047
C C F +C+ + G+C+C P + G C +
Sbjct: 417 NHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC----------------DV 460
Query: 1048 CQNGGTCDPVSGHCAC-PEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLC--DPHTGRC 1104
C G T G +C P + ++ LP C S G C DP GRC
Sbjct: 461 CAEGFT-----GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRC 515
Query: 1105 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCP-PGAA---CHHVTGACRCPPGFTGSGCEQ 1160
LC + G C+ C G++G C Q C C PG A C TG CRC GF G+ C++
Sbjct: 516 LCKPNFQGTHCEL-CAPGFYGPGC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDR 573
Query: 1161 ACPPGSFGEDCAQMCQCP--GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG-PGCEQ 1217
C PG F Q+C C G P G C C + GP C RC PG +G P C Q
Sbjct: 574 -CAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCD-RCRPGYHGFPNC-Q 630
Query: 1218 LCGCLNGGSCDAATGA---CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQG---AACD 1271
C C G+ D GA CRC G+ GT C P P+C +G AACD
Sbjct: 631 ACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACD 690
Query: 1272 PVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNG------SCSCGLG 1325
P +G C C P G+RC+ P CE SC GL C C
Sbjct: 691 PRSGQCSCRPRVTGLRCDTCVPGAYNFPYCE-AGSCHPAGLAPVDPALPEAQVPCMCRAH 749
Query: 1326 WTGRHCELACPPGRYGAACH-----LECSCHNNST------CEPATGTCRCGPGFYGQAC 1374
G C+ C PG +G + CSC T C+P TG C C P GQAC
Sbjct: 750 VEGPSCD-RCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC 808
Query: 1375 EHPCPPGFHGA------GCQGLCWCQHGAP----CDPISGRCLCPAGFHGHFCERGCEPG 1424
C GF G GC+ C C G C+P +G C C G C
Sbjct: 809 AS-CKDGFFGLDQADYFGCRS-CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
Query: 1425 SFGEGCHQRCDCDGGA 1440
+ H R + + A
Sbjct: 867 YLPDLHHLRLELEEAA 882
Score = 198 bits (503), Expect = 4e-50
Identities = 176/578 (30%), Positives = 221/578 (38%), Gaps = 125/578 (21%)
Query: 514 DSFGHDCSLTCDDCRNGGTCLLGLDGCDCP----EGWTGLICN-----ETCPPDTFGKNC 564
D F C TC GGTC D C CP + W N ++C +C
Sbjct: 316 DPFRLQC--TCQHNTCGGTC----DRC-CPGFNQQPWKPATANSANECQSCNCYGHATDC 368
Query: 565 SFSCSCQNGGTCDSVTGACR-------CPPGVSGTNCEDGCPKGYY--------GKHCRK 609
+ S+ G + C +G NCE C G+Y H +
Sbjct: 369 YYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCER-CLPGFYRSPNHPLDSPHVCR 427
Query: 610 KCNCANR---GRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSE-------------- 652
+CNC + G C L G C C P G C + + P C
Sbjct: 428 RCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP 487
Query: 653 -----ECQCVQPHTQ--SC--DKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPV 703
C C TQ +C D R G C CK F+G C+ C G++GPGC Q C C
Sbjct: 488 AGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFYGPGC-QPCQCSS 545
Query: 704 -GVA---CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG--GAPCHGV--T 755
GVA CD +G+C RC GF+G C + C G F C C G G
Sbjct: 546 PGVADDRCDPDTGQC--RCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEA 602
Query: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPET---------GACLCLP 806
G+C C P G C+ C G G P CQ A CDP G C C P
Sbjct: 603 GRCLCQPEFAGPHCDR-CRPGYHGF------PNCQ-ACTCDPRGALDQLCGAGGLCRCRP 654
Query: 807 GFVGSRCQDVCPAGWYG-PSCQTRCSCANDGH----CHPATGHCSCAPGWTGFSCQRACD 861
G+ G+ CQ+ C G++G PSC C C+ +G C P +G CSC P TG C
Sbjct: 655 GYTGTACQE-CSPGFHGFPSC-VPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVP 712
Query: 862 TGHWGPDCS----HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG------P 911
+ P C HP + + C+C A GP C++ C G +G
Sbjct: 713 GAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSPSNPE 771
Query: 912 GCEQRCQCQHG------AACDHVSGACTCPAGWRGTFCEHACPAGFFGLD------CRSA 959
GC RC C A C +G C C G C +C GFFGLD CRS
Sbjct: 772 GCT-RCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQADYFGCRS- 828
Query: 960 CNCTAGAA----CDAVNGSCLCPAGRRGPRCAETCPAH 993
C C G A C+ G C C +GP C+E H
Sbjct: 829 CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
Score = 185 bits (470), Expect = 3e-46
Identities = 169/598 (28%), Positives = 218/598 (36%), Gaps = 119/598 (19%)
Query: 551 CNETCPPDTFGKNCSFSCSCQN---GGTCDSVTGACRCPPGVS----------------G 591
C+ P D F C+CQ+ GGTCD RC PG +
Sbjct: 309 CDAKDPTDPF----RLQCTCQHNTCGGTCD------RCCPGFNQQPWKPATANSANECQS 358
Query: 592 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACL-CDPGLYGRFCHLTCPPWAFGPG- 649
NC YY ++ + ++ G C+ C G C P + P
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
Query: 650 ------CSEECQCVQPHTQ-SCDKRDGSCSCKAGFRGERCQAECELGYFG-PGCWQACTC 701
C C T +C+ G C C+ F GERC C G+ G P C+
Sbjct: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAEGFTGFPSCY----- 472
Query: 702 PVGVACDSVSGECGKRCPAGFQGEDCGQEC-PVGTFGVNCSSSCSCGGAPCHGV-----T 755
P D ++ P G VNC CS G +
Sbjct: 473 -----------------PTPSSSNDTREQVLPAGQI-VNCD--CSAAGTQGNACRKDPRV 512
Query: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA--RCDPETGACLCLPGFVGSRC 813
G+C C P G CE C G +G GCQ + A RCDP+TG C C GF G+ C
Sbjct: 513 GRCLCKPNFQGTHCEL-CAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATC 571
Query: 814 QDVCPAGWYGPSCQTRCSCANDG----HCHPATGHCSCAPGWTGFSCQRACDTGHWGPDC 869
P ++ P CQ C C+ G C A G C C P + G C R H P+C
Sbjct: 572 DRCAPGYFHFPLCQL-CGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCDRCRPGYHGFPNC 629
Query: 870 SHPCNCSAGHGSCDAI---SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQH----G 922
C C G+ D + GLC C GY G C++ P H P C C C
Sbjct: 630 -QACTCDP-RGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVP-CHCSAEGSLH 686
Query: 923 AACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAG-----AACDAVNGSCLC 977
AACD SG C+C G C+ P + C + AG A C+C
Sbjct: 687 AACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMC 746
Query: 978 PAGRRGPRCAETCPAHTYG------HNCSQACACFNG-----ASCDPVHGQCHCAPGWMG 1026
A GP C + C +G C++ G A C P GQC C P G
Sbjct: 747 RAHVEGPSC-DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCG 805
Query: 1027 PSCLQACPAGLYG------DNCRHSCLCQNGG----TCDPVSGHCACPEGWAGLACEK 1074
+C +C G +G CR SC C GG +C+P +G C C G C +
Sbjct: 806 QAC-ASCKDGFFGLDQADYFGCR-SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
Score = 176 bits (446), Expect = 2e-43
Identities = 172/566 (30%), Positives = 208/566 (36%), Gaps = 119/566 (21%)
Query: 569 SCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYG---A 625
+C D C C G C+ CP N AN + YG
Sbjct: 308 ACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATD 367
Query: 626 CLCDP------------GLY--GRFC-----HLT------CPPWAF--------GPGCSE 652
C DP G Y G C H T C P + P
Sbjct: 368 CYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCR 427
Query: 653 ECQCVQPHTQ-SCDKRDGSCSCKAGFRGERCQAECELGYFG-PGCWQA------------ 698
C C T +C+ G C C+ F GERC C G+ G P C+
Sbjct: 428 RCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAEGFTGFPSCYPTPSSSNDTREQVL 486
Query: 699 -------CTCPV----GVAC--DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCS-SSC 744
C C G AC D G C C FQG C + C G +G C C
Sbjct: 487 PAGQIVNCDCSAAGTQGNACRKDPRVGRC--LCKPNFQGTHC-ELCAPGFYGPGCQPCQC 543
Query: 745 SCGGAP---CHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEIC---PACQHAARCDPE 798
S G C TGQCRC G G C+ C G + ++C PA CD E
Sbjct: 544 SSPGVADDRCDPDTGQCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCD-E 601
Query: 799 TGACLCLPGFVGSRCQDVCPAGWYG-PSCQTRCSC----ANDGHCHPATGHCSCAPGWTG 853
G CLC P F G C D C G++G P+CQ C+C A D C A G C C PG+TG
Sbjct: 602 AGRCLCQPEFAGPHC-DRCRPGYHGFPNCQA-CTCDPRGALDQLC-GAGGLCRCRPGYTG 658
Query: 854 FSCQRACDTGHWGPDCSHPCNCSAG---HGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG 910
+CQ H P C PC+CSA H +CD SG C C G RC+ P +
Sbjct: 659 TACQECSPGFHGFPSCV-PCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNF 717
Query: 911 PGCEQRCQCQHGAACDHVSGA-------CTCPAGWRGTFCEHACPAGFFGLDCRSACNCT 963
P CE C H A V A C C A G C+ C GF+GL + CT
Sbjct: 718 PYCEAG-SC-HPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSPSNPEGCT 774
Query: 964 -----------AGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCS-----QACAC-- 1005
A C G C C G CA +C +G + + ++C C
Sbjct: 775 RCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQADYFGCRSCRCDI 833
Query: 1006 --FNGASCDPVHGQCHCAPGWMGPSC 1029
G SC+P G C C P GP+C
Sbjct: 834 GGALGQSCEPRTGVCRCRPNTQGPTC 859
Score = 176 bits (445), Expect = 2e-43
Identities = 166/576 (28%), Positives = 211/576 (36%), Gaps = 128/576 (22%)
Query: 782 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGP----------SCQTRCS 831
C AC DP C C G C CP P CQ+ C+
Sbjct: 302 CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS-CN 360
Query: 832 C---ANDGHCHPAT----------------GHC-SCAPGWTGFSCQRACDTGHW------ 865
C A D + P G C C TG +C+R C G +
Sbjct: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCER-CLPGFYRSPNHP 419
Query: 866 --GPDCSHPCNCSAG--HGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG-PGC------- 913
P CNC + G+C+ ++G C C + G RC+ C +G G P C
Sbjct: 420 LDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD-VCAEGFTGFPSCYPTPSSS 478
Query: 914 ----EQ--------RCQCQ----HGAAC--DHVSGACTCPAGWRGTFCEHACPAGFFGLD 955
EQ C C G AC D G C C ++GT CE C GF+G
Sbjct: 479 NDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCE-LCAPGFYGPG 537
Query: 956 CRSACNCT----AGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGAS- 1010
C+ C C+ A CD G C C G G C P + + C Q C C +
Sbjct: 538 CQ-PCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLC-QLCGCSPAGTL 595
Query: 1011 ---CDPVHGQCHCAPGWMGPSCLQACPAGLYG-DNCRHSCLCQNGGTCDPV---SGHCAC 1063
CD G+C C P + GP C C G +G NC+ +C C G D + G C C
Sbjct: 596 PEGCDEA-GRCLCQPEFAGPHC-DRCRPGYHGFPNCQ-ACTCDPRGALDQLCGAGGLCRC 652
Query: 1064 PEGWAGLACEKEC------LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQS 1117
G+ G AC+ EC P V C G CDP +G+C C TG +C +
Sbjct: 653 RPGYTGTACQ-ECSPGFHGFPSCVPCHCSAEGSL--HAACDPRSGQCSCRPRVTGLRCDT 709
Query: 1118 PCLRGWFGEACAQRCSCPPGA------ACHHVTGACRCPPGFTGSGCEQACPPGSFG--- 1168
C+ G + + SC P A C C G C++ C PG +G
Sbjct: 710 -CVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSP 767
Query: 1169 ---EDCAQMCQCP-----GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGP------G 1214
E C + C C G C P TG C C G +C C G +G G
Sbjct: 768 SNPEGCTR-CSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS-CKDGFFGLDQADYFG 825
Query: 1215 CEQLCGCLNGG----SCDAATGACRCPTGFLGTDCN 1246
C C C GG SC+ TG CRC G C+
Sbjct: 826 CRS-CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCS 860
Score = 162 bits (411), Expect = 2e-39
Identities = 144/458 (31%), Positives = 175/458 (38%), Gaps = 95/458 (20%)
Query: 1102 GRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVT--GAC-RCPPGFTGSGC 1158
GRC+C D C + F C C H T G C RC PGF
Sbjct: 298 GRCVCHGH--ADACDAKDPTDPFRLQCT----------CQHNTCGGTCDRCCPGFNQQPW 345
Query: 1159 EQACPPGSFGEDCAQMCQCPGENPACH------------------PATGTC-SCAAGYHG 1199
+ A + +C Q C C G C+ G C C G
Sbjct: 346 KPAT--ANSANEC-QSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTG 402
Query: 1200 PSCQQRCPPGRY--------GPGCEQLCGC---LNGGSCDAATGACRCPTGFLGTDCNLT 1248
+C+ RC PG Y P + C C G+C+ TG C C F G C++
Sbjct: 403 VNCE-RCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV- 460
Query: 1249 CPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1308
C +G P +C P + E+ P + V C+ + +
Sbjct: 461 ---------------CAEGFTGFP---SCYPTPSSSNDTREQVLPAGQI-VNCDCSAAGT 501
Query: 1309 NGGLCHASN--GSCSCGLGWTGRHCELACPPGRYGAACHLECSCHN----NSTCEPATGT 1362
G C G C C + G HCEL C PG YG C C C + + C+P TG
Sbjct: 502 QGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFYGPGCQ-PCQCSSPGVADDRCDPDTGQ 559
Query: 1363 CRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAP----CDPISGRCLCPAGFHGHFCE 1418
CRC GF G C+ P FH CQ LC C CD +GRCLC F G C+
Sbjct: 560 CRCRVGFEGATCDRCAPGYFHFPLCQ-LCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCD 617
Query: 1419 RGCEPGSFGEGCHQRCDCDGGAPCDPVT---GLCLCPPGRSGATCNLDCRRGQFG-PSCT 1474
R C PG G Q C CD D + GLC C PG +G C +C G G PSC
Sbjct: 618 R-CRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ-ECSPGFHGFPSCV 675
Query: 1475 -LHCDCGGG--ADCDPVSGQCHC---VDGYMGPTCREG 1506
HC G A CDP SGQC C V G TC G
Sbjct: 676 PCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPG 713
Score = 151 bits (382), Expect = 4e-36
Identities = 125/389 (32%), Positives = 155/389 (39%), Gaps = 88/389 (22%)
Query: 1147 CRCPPGFTGSGCEQACP------PGSFGEDCAQMCQCPGENPACHPATGTC-SCAAGYHG 1199
C CP + G C++ P G F C CQC G + C P +G C C G
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSDRCLPGSGVCVDCQHNTEG 1889
Query: 1200 PSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCT 1259
C+ RC G + C++ CP C L+ P F C
Sbjct: 1890 AHCE-RCQAGFVSSRDDPSAPCVS------------CP-------CPLSVPSNNFAEGCV 1929
Query: 1260 HVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP-----QNRFGVGCEHTCSCRNGGL-- 1312
G Q CLC PG AG CER P G C+ C C G
Sbjct: 1930 LRGGRTQ----------CLCKPGYAGASCERCAPGFFGNPLVLGSSCQ-PCDCSGNGDPN 1978
Query: 1313 -----CHASNGSC-SCGLGWTGRHCELACPPGRYGAAC------HLECSCHNNSTCEPAT 1360
C G+C C TG CE+ C PG YG A +C+ C+P +
Sbjct: 1979 LLFSDCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPHS 2037
Query: 1361 GTCRCGPGFYGQACEHPCPPGFHGA-GCQGL--CWC---QHGAPCDPISGRCLCPAGFHG 1414
G C C G G+ C+ C G G GC G C C G+ C P SG+C C G G
Sbjct: 2038 GHCLCKAGVTGRRCDR-CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMG 2096
Query: 1415 HFCERGCEPGSFG---EGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQF-- 1469
C R C PG +G +GC +RC C GG CDP TG C CPPG SG C+ ++ Q
Sbjct: 2097 PQC-RECAPGYWGLPEQGC-RRCQCPGGR-CDPHTGRCNCPPGLSGERCDTCSQQHQVPV 2153
Query: 1470 --GP-SCTLHCDCGGGADCDPVSGQCHCV 1495
GP ++HC+ CD HCV
Sbjct: 2154 PGGPVGHSIHCEV-----CD------HCV 2171
Score = 140 bits (354), Expect = 7e-33
Identities = 117/352 (33%), Positives = 140/352 (39%), Gaps = 68/352 (19%)
Query: 877 AGHGSCDAISGLCLCEAGYVGPRCEQQCP------QGHFGPGCEQRCQCQ-HGAACDHVS 929
AG G+ + LCLC A Y G C++ P +G F C CQC H C S
Sbjct: 1819 AGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSDRCLPGS 1877
Query: 930 GACT-CPAGWRGTFCEHACPAGFFGL--DCRSAC------------NCTAGAACDAVNGS 974
G C C G CE C AGF D + C N G
Sbjct: 1878 GVCVDCQHNTEGAHCER-CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQ 1936
Query: 975 CLCPAGRRGPRCAETCPAH-----TYGHNCSQACACF-NG------ASCDPVHGQCH-CA 1021
CLC G G C P G +C Q C C NG + CDP+ G C C
Sbjct: 1937 CLCKPGYAGASCERCAPGFFGNPLVLGSSC-QPCDCSGNGDPNLLFSDCDPLTGACRGCL 1995
Query: 1022 PGWMGPSCLQACPAGLYGD-----NCRHSCLCQNGGT--CDPVSGHCACPEGWAGLACEK 1074
GP C + C G YG+ NC C C GT CDP SGHC C G G C++
Sbjct: 1996 RHTTGPRC-EICAPGFYGNALLPGNCTR-CDCTPCGTEACDPHSGHCLCKAGVTGRRCDR 2053
Query: 1075 EC----LPRDVRAGCR--HSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG--E 1126
C D GCR G G C P +G+C C G G +C+ C G++G E
Sbjct: 2054 -CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGLPE 2111
Query: 1127 ACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCP 1178
+RC C PG C TG C CPPG +G C + C+Q Q P
Sbjct: 2112 QGCRRCQC-PGGRCDPHTGRCNCPPGLSGERC----------DTCSQQHQVP 2152
Score = 140 bits (352), Expect = 1e-32
Identities = 112/342 (32%), Positives = 139/342 (40%), Gaps = 59/342 (17%)
Query: 1191 CSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCP 1250
C C A Y G SCQ+ C PG Y G C + C G+ + C
Sbjct: 1831 CLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCVPCQCHGHSDRC-----LPGSGVCVDCQ 1884
Query: 1251 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG 1310
G +C C G ++ D + C+ P C P N F GC
Sbjct: 1885 HNTEGAHCER-CQAGFVSSRDDPSAPCVSCP------CPLSVPSNNFAEGC--------- 1928
Query: 1311 GLCHASNGSCSCGLGWTGRHCELACPPGRYG------AACHLECSCHNN-------STCE 1357
+ C C G+ G CE C PG +G ++C C C N S C+
Sbjct: 1929 -VLRGGRTQCLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQ-PCDCSGNGDPNLLFSDCD 1985
Query: 1358 PATGTCR-CGPGFYGQACEHPCPPGFHG-AGCQGLCWCQHGAPC-----DPISGRCLCPA 1410
P TG CR C G CE C PGF+G A G C PC DP SG CLC A
Sbjct: 1986 PLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKA 2044
Query: 1411 GFHGHFCERGCEPGSFG-EGCH--QRCDCDG---GAPCDPVTGLCLCPPGRSGATCNLDC 1464
G G C+R C+ G FG +GC + C C G+ C P +G C C PG G C +C
Sbjct: 2045 GVTGRRCDR-CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR-EC 2102
Query: 1465 RRGQFG---PSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1503
G +G C C C GG CDP +G+C+C G G C
Sbjct: 2103 APGYWGLPEQGCR-RCQCPGGR-CDPHTGRCNCPPGLSGERC 2142
Score = 129 bits (325), Expect = 2e-29
Identities = 122/395 (30%), Positives = 149/395 (37%), Gaps = 91/395 (23%)
Query: 787 PACQHAARCDPETGACLCLPGFVGSRCQDVCPA------GWYGPSCQTRCSC-ANDGHCH 839
PA Q A + E CLC + G CQ+ P G + C C C + C
Sbjct: 1818 PAGQGALASNVEL--CLCPASYRGDSCQECAPGFYRDVKGLFLGRC-VPCQCHGHSDRCL 1874
Query: 840 PATGHC-SCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGH-GSCDAISGLCLCEAGYVG 897
P +G C C G C+R C AG S D S C V
Sbjct: 1875 PGSGVCVDCQHNTEGAHCER----------------CQAGFVSSRDDPSAPC------VS 1912
Query: 898 PRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG---- 953
C P +F GC R G C C G+ G CE P GFFG
Sbjct: 1913 CPCPLSVPSNNFAEGCVLR-----GGRTQ-----CLCKPGYAGASCERCAP-GFFGNPLV 1961
Query: 954 --LDCRSACNCTAG-------AACDAVNGSCL-CPAGRRGPRCAETCPAHTYGH-----N 998
C+ C+C+ + CD + G+C C GPRC E C YG+ N
Sbjct: 1962 LGSSCQP-CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC-EICAPGFYGNALLPGN 2019
Query: 999 CSQA-CACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYG-DNCR--HSCLC---QNG 1051
C++ C +CDP G C C G G C C G +G D C C C G
Sbjct: 2020 CTRCDCTPCGTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFDGCGGCRPCACGPAAEG 2078
Query: 1052 GTCDPVSGHCACPEGWAGLACEKECLPRD---VRAGCRHSGGCLNGGLCDPHTGRCLCPA 1108
C P SG C C G G C +EC P GCR GG CDPHTGRC CP
Sbjct: 2079 SECHPQSGQCHCRPGTMGPQC-RECAPGYWGLPEQGCRRCQ--CPGGRCDPHTGRCNCPP 2135
Query: 1109 GWTGDKCQSPCLRGWFGEACAQRCSCP-PGAACHH 1142
G +G++C + C+Q+ P PG H
Sbjct: 2136 GLSGERC----------DTCSQQHQVPVPGGPVGH 2160
Score = 129 bits (324), Expect = 2e-29
Identities = 116/362 (32%), Positives = 139/362 (38%), Gaps = 76/362 (20%)
Query: 975 CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCH-----CAPGWMGPSC 1029
CLCPA RG C E P F G C P QCH C PG C
Sbjct: 1831 CLCPASYRGDSCQECAPGFY-----RDVKGLFLGR-CVPC--QCHGHSDRCLPG--SGVC 1880
Query: 1030 LQACPAGLYGDNCRHSCLCQNGGTC---DPVSGHCACPEGWAGLACEKECLPRDVRAGCR 1086
+ C G +C CQ G DP + +CP C + GC
Sbjct: 1881 VD-CQHNTEGAHCER---CQAGFVSSRDDPSAPCVSCP-------CPLSVPSNNFAEGCV 1929
Query: 1087 HSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPG--------- 1137
GG +CLC G+ G C+ C G+FG SC P
Sbjct: 1930 LRGG----------RTQCLCKPGYAGASCER-CAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
Query: 1138 ---AACHHVTGACR-CPPGFTGSGCEQACPPGSFGE-----DCAQMCQC-PGENPACHPA 1187
+ C +TGACR C TG CE C PG +G +C + C C P AC P
Sbjct: 1979 LLFSDCDPLTGACRGCLRHTTGPRCE-ICAPGFYGNALLPGNCTR-CDCTPCGTEACDPH 2036
Query: 1188 TGTCSCAAGYHGPSCQQRCPPGRYG----PGCEQLCGC---LNGGSCDAATGACRCPTGF 1240
+G C C AG G C RC G +G GC C C G C +G C C G
Sbjct: 2037 SGHCLCKAGVTGRRCD-RCQEGHFGFDGCGGCRP-CACGPAAEGSECHPQSGQCHCRPGT 2094
Query: 1241 LGTDCNLTCPQGRFG---PNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRF 1297
+G C C G +G C C C G CDP TG C CPPG +G RC+ Q++
Sbjct: 2095 MGPQCR-ECAPGYWGLPEQGCRR-CQC-PGGRCDPHTGRCNCPPGLSGERCDTCSQQHQV 2151
Query: 1298 GV 1299
V
Sbjct: 2152 PV 2153
Score = 122 bits (306), Expect = 3e-27
Identities = 119/405 (29%), Positives = 154/405 (38%), Gaps = 67/405 (16%)
Query: 531 GTCLLGLDGCDCPEGWTGLICNETCPP---DTFGKNCSFSCSCQNGGTCDSVTGACRCPP 587
G ++ C CP + G C E P D G CQ G D RC P
Sbjct: 1822 GALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSD------RCLP 1875
Query: 588 GVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFG 647
G SG C D C G HC ++C C+ P C L+ P F
Sbjct: 1876 G-SGV-CVD-CQHNTEGAHC-ERCQAGFVSSRDDPSAPCVSCP------CPLSVPSNNFA 1925
Query: 648 PGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGP-----GCWQACTCP 702
GC Q C CK G+ G C+ C G+FG Q C C
Sbjct: 1926 EGCVLRGGRTQ------------CLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQPCDCS 1972
Query: 703 -------VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGV-----NCSS-SCS-CGG 748
+ CD ++G C + C G C + C G +G NC+ C+ CG
Sbjct: 1973 GNGDPNLLFSDCDPLTGAC-RGCLRHTTGPRC-EICAPGFYGNALLPGNCTRCDCTPCGT 2030
Query: 749 APCHGVTGQCRCPPGRTGEDCEADCPEGRWGL----GCQEI-CPACQHAARCDPETGACL 803
C +G C C G TG C+ C EG +G GC+ C + C P++G C
Sbjct: 2031 EACDPHSGHCLCKAGVTGRRCDR-CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCH 2089
Query: 804 CLPGFVGSRCQDVCPAGWYGPS--CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACD 861
C PG +G +C++ P W P C+ RC C G C P TG C+C PG +G C C
Sbjct: 2090 CRPGTMGPQCRECAPGYWGLPEQGCR-RCQCPG-GRCDPHTGRCNCPPGLSGERCD-TCS 2146
Query: 862 TGHWGPDCSHPCNCSAGHGSCDAISGLCLCE---AGYVGPRCEQQ 903
H P P S CD L L + AG + P +Q
Sbjct: 2147 QQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQ 2191
Score = 110 bits (274), Expect = 1e-23
Identities = 77/231 (33%), Positives = 98/231 (42%), Gaps = 26/231 (11%)
Query: 547 TGLIC-NETCPPDTFGKNCSFSCSCQN----GGTCDSVTGACRCPPGVSGTNCEDGCPKG 601
+ L C N F N + C C G TC+ G C C V G +C C G
Sbjct: 1416 SSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATG 1474
Query: 602 YYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFG----PGCSEECQCV 657
Y+G + C+C R C L G C+C P C L C P FG GC EEC C
Sbjct: 1475 YWGFPNCRPCDCGAR-LCDELTGQCICPPRTIPPDC-LLCQPQTFGCHPLVGC-EECNCS 1531
Query: 658 QPHTQ-----SCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTC-PVGVA---CD 708
P Q +CD G C C+ G RC C G+ G + C C G A CD
Sbjct: 1532 GPGIQELTDPTCDTDSGQCKCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCD 1590
Query: 709 SVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCR 759
++G+C C QG C Q C +GTF ++ ++ C C G T +CR
Sbjct: 1591 PLTGQC--YCKENVQGPKCDQ-CSLGTFSLDAANPKGCTRCFCFGATERCR 1638
Score = 97.8 bits (242), Expect = 7e-20
Identities = 73/242 (30%), Positives = 99/242 (40%), Gaps = 34/242 (14%)
Query: 650 CSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAEC-ELGYFGPGCWQACTCPVGVACD 708
C+ + + P + S R+ + S + C E+G GP C+
Sbjct: 1404 CAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGP------------TCE 1451
Query: 709 SVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGED 768
G+C C A G DC + C G +G C CG C +TGQC CPP D
Sbjct: 1452 PFGGQCP--CHAHVIGRDCSR-CATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPD 1508
Query: 769 CEADCPEGRWG----LGCQEI-C--PACQHAA--RCDPETGACLCLPGFVGSRCQDVCPA 819
C C +G +GC+E C P Q CD ++G C C P G RC D C
Sbjct: 1509 CLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC-DTCSP 1566
Query: 820 GWYG-PSCQTRCSC----ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN 874
G++G P C+ C C G C P TG C C G C + C G + D ++P
Sbjct: 1567 GFHGYPRCRP-CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKG 1624
Query: 875 CS 876
C+
Sbjct: 1625 CT 1626
Score = 91.3 bits (225), Expect = 7e-18
Identities = 73/247 (29%), Positives = 91/247 (36%), Gaps = 48/247 (19%)
Query: 997 HNCSQACACFN----GASCDPVHGQCHCAPGWMGPSCLQACPAGLYG-DNCRHSCLCQNG 1051
+N ++ C C G +C+P GQC C +G C + C G +G NCR C C
Sbjct: 1432 NNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCR-PCDC-GA 1488
Query: 1052 GTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWT 1111
CD ++G C CP PR + C LC P T C G
Sbjct: 1489 RLCDELTGQCICP-------------PRTIPPDCL---------LCQPQTFGCHPLVGCE 1526
Query: 1112 GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDC 1171
C P + Q + P C +G C+C P TG C+ C PG G
Sbjct: 1527 ECNCSGPGI---------QELTDP---TCDTDSGQCKCRPNVTGRRCD-TCSPGFHGYPR 1573
Query: 1172 AQMCQCPGENPA---CHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCD 1228
+ C C A C P TG C C GP C Q C G + GC C
Sbjct: 1574 CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGCTR-CFCF 1631
Query: 1229 AATGACR 1235
AT CR
Sbjct: 1632 GATERCR 1638
Score = 90.5 bits (223), Expect = 1e-17
Identities = 66/207 (31%), Positives = 81/207 (39%), Gaps = 35/207 (16%)
Query: 739 NCSSSCSCG-----GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA 793
N + C C G C GQC C G DC C G WG C C A
Sbjct: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGF---PNCRPCDCGA 1488
Query: 794 R-CDPETGACLCLPGFVGSRCQDVCPAGWYG----PSCQTRCSCANDG-------HCHPA 841
R CD TG C+C P + C +C +G C+ C+C+ G C
Sbjct: 1489 RLCDELTGQCICPPRTIPPDCL-LCQPQTFGCHPLVGCE-ECNCSGPGIQELTDPTCDTD 1546
Query: 842 TGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNC---SAGHGSCDAISGLCLCEAGYVGP 898
+G C C P TG C H P C PC+C G CD ++G C C+ GP
Sbjct: 1547 SGQCKCRPNVTGRRCDTCSPGFHGYPRC-RPCDCHEAGTAPGVCDPLTGQCYCKENVQGP 1605
Query: 899 RCEQQCPQGHFG------PGCEQRCQC 919
+C+ QC G F GC RC C
Sbjct: 1606 KCD-QCSLGTFSLDAANPKGC-TRCFC 1630
Score = 90.1 bits (222), Expect = 1e-17
Identities = 68/211 (32%), Positives = 86/211 (40%), Gaps = 34/211 (16%)
Query: 1254 FGPNCTHVCGCGQ----GAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN 1309
F N CGC + G C+P G C C G C R C +G C C
Sbjct: 1430 FYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC-G 1487
Query: 1310 GGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHL-----ECSCHN-------NSTCE 1357
LC G C C C L C P +G CH EC+C + TC+
Sbjct: 1488 ARLCDELTGQCICPPRTIPPDC-LLCQPQTFG--CHPLVGCEECNCSGPGIQELTDPTCD 1544
Query: 1358 PATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG--AP--CDPISGRCLCPAGFH 1413
+G C+C P G+ C+ C PGFHG C C AP CDP++G+C C
Sbjct: 1545 TDSGQCKCRPNVTGRRCD-TCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQ 1603
Query: 1414 GHFCERGCEPGSFG------EGCHQRCDCDG 1438
G C++ C G+F +GC RC C G
Sbjct: 1604 GPKCDQ-CSLGTFSLDAANPKGC-TRCFCFG 1632
Score = 89.7 bits (221), Expect = 2e-17
Identities = 84/301 (27%), Positives = 103/301 (34%), Gaps = 43/301 (14%)
Query: 1260 HVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP---QNRFGVGCEHTCSCRNGGLCHAS 1316
H C DP C C G C+R CP Q + ++ + C+
Sbjct: 305 HADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGH 364
Query: 1317 NGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNST-CEPATGTCRCGPGFYGQACE 1375
C R + G ++C H CE RC PGFY ++
Sbjct: 365 ATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE------RCLPGFY-RSPN 417
Query: 1376 HPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCE-----------PG 1424
HP C G C+ ++GRC C F G C+ E P
Sbjct: 418 HPLDSPHVCRRCNCESDFTDGT-CEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPS 476
Query: 1425 SFGEGCHQ--------RCDCDG----GAPC--DPVTGLCLCPPGRSGATCNLDCRRGQFG 1470
S + Q CDC G C DP G CLC P G C L C G +G
Sbjct: 477 SSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFYG 535
Query: 1471 PSCT-LHCDCGGGAD--CDPVSGQCHCVDGYMGPTCREGGP--LRLPENPSLAQGSAGTL 1525
P C C G AD CDP +GQC C G+ G TC P P AGTL
Sbjct: 536 PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTL 595
Query: 1526 P 1526
P
Sbjct: 596 P 596
Score = 89.4 bits (220), Expect = 3e-17
Identities = 61/178 (34%), Positives = 79/178 (44%), Gaps = 30/178 (16%)
Query: 1348 CSCHN----NSTCEPATGTCRCGPGFYGQACEHPCPPGFHG-AGCQGLCWCQHGAP-CDP 1401
C CH TCEP G C C G+ C C G+ G C+ C GA CD
Sbjct: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRP---CDCGARLCDE 1493
Query: 1402 ISGRCLCPAGFHGHFCERGCEPGSFGEGCH-----QRCDCDGGA-------PCDPVTGLC 1449
++G+C+CP C C+P +FG CH + C+C G CD +G C
Sbjct: 1494 LTGQCICPPRTIPPDCLL-CQPQTFG--CHPLVGCEECNCSGPGIQELTDPTCDTDSGQC 1550
Query: 1450 LCPPGRSGATCNLDCRRGQFGPSCTLHCDC--GGGAD--CDPVSGQCHCVDGYMGPTC 1503
C P +G C+ C G G CDC G A CDP++GQC+C + GP C
Sbjct: 1551 KCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC 1607
Score = 88.2 bits (217), Expect = 6e-17
Identities = 74/278 (26%), Positives = 109/278 (39%), Gaps = 40/278 (14%)
Query: 837 HCHPATGHCSCAPGWTGFSCQRACDT-GHWGPDCSHPCNC---SAGHGSCDAISGLCLCE 892
HC H S P + C+ A + + + + PC C A +C+ G C C
Sbjct: 1403 HCAAQGYHIS--PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCH 1460
Query: 893 AGYVGPRCEQQCPQGHFG-PGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF 951
A +G C + C G++G P C C C CD ++G C CP C C
Sbjct: 1461 AHVIGRDCSR-CATGYWGFPNCRP-CDCG-ARLCDELTGQCICPPRTIPPDCL-LCQPQT 1516
Query: 952 FG----LDCRSACNCTAGA-------ACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCS 1000
FG + C CNC+ CD +G C C G RC +TC +G+
Sbjct: 1517 FGCHPLVGCEE-CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC-DTCSPGFHGYPRC 1574
Query: 1001 QACACFNGAS----CDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDP 1056
+ C C + CDP+ GQC+C GP C Q C G + + + C C
Sbjct: 1575 RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGCTR-CFCFG 1632
Query: 1057 VSGHCACP----------EGWAGLACEKECLPRDVRAG 1084
+ C EGW L+ +++ +P + + G
Sbjct: 1633 ATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPG 1670
Score = 79.0 bits (193), Expect = 3e-14
Identities = 66/226 (29%), Positives = 80/226 (35%), Gaps = 25/226 (11%)
Query: 942 FCEHACPA-GFFGLDCRSACNC----TAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
FC +A + F + C C G C+ G C C A G C+ +
Sbjct: 1419 FCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF 1478
Query: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPA--GLYGDNCRHSCLCQNGG-- 1052
NC + C C CD + GQC C P + P CL P G + C C G
Sbjct: 1479 PNC-RPCDC-GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQ 1536
Query: 1053 -----TCDPVSGHCACPEGWAGLACEK-----ECLPRDVRAGCRHSGGCLNGGLCDPHTG 1102
TCD SG C C G C+ PR C +G G+CDP TG
Sbjct: 1537 ELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTA--PGVCDPLTG 1594
Query: 1103 RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACR 1148
+C C G KC C G F A C C T CR
Sbjct: 1595 QCYCKENVQGPKCDQ-CSLGTFSLDAANPKGC-TRCFCFGATERCR 1638
Score = 78.6 bits (192), Expect = 4e-14
Identities = 146/634 (23%), Positives = 197/634 (31%), Gaps = 151/634 (23%)
Query: 100 YTTEARTVLRCCRGWMQQPDEEGCLSA--ECSASLCFHGGRCVPGSAQPCHCPPGFQGPR 157
+ T T RCC G+ QQP + ++ EC + C+ G A C+ P R
Sbjct: 326 HNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCY-------GHATDCYYDPEVDRRR 378
Query: 158 CQYDVDECRTHNGG-----CQHRCVNTPGSYLCECKPGFRLHTDS--RTCLAINSCALGN 210
+D T+ GG CQH +T G C PGF + + C +
Sbjct: 379 ASQSLDG--TYQGGGVCIDCQH---HTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCES 433
Query: 211 GGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC----------VRRSPCANRNGSCMHRCQ 260
C LT RC CRP F G C P + + +
Sbjct: 434 DFTDGTCEDLT---GRCYCRPNF----SGERCDVCAEGFTGFPSCYPTPSSSNDTREQVL 486
Query: 261 VVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGAD 320
+ C+C G AC + G C N QG+ +C G+
Sbjct: 487 PAGQIVNCDCSAA---GTQGNACR--KDPRVGRCLCKP---NFQGTHCELCAPGFY---- 534
Query: 321 GRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS- 379
G C C+ ++ G + G C C G+E TC D CA
Sbjct: 535 GPGC--------QPCQCSSPGVADDRCDPDTGQ-CRCRVGFE----GATC---DRCAPGY 578
Query: 380 ---PCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQC 436
P CQ CGC L GC++ C HC
Sbjct: 579 FHFPLCQL----------CGCSPAGTLPE---GCDEAGRCLCQPEFAGPHCDR------- 618
Query: 437 SCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEE 496
C GY + + C+ D G L D +
Sbjct: 619 -CRPGYHGFPNCQACT------CDPRGAL----------------------DQLCGAGGL 649
Query: 497 AELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNG---GTCLLGLDGCDCPEGWTGLICNE 553
R +T T C G + C G C C C TGL C +
Sbjct: 650 CRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC-D 708
Query: 554 TCPPDTFGKNCSFSCSCQNGG------TCDSVTGACRCPPGVSGTNCEDGCPKGYYG--- 604
TC P + + SC G C C V G +C D C G++G
Sbjct: 709 TCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC-DRCKPGFWGLSP 767
Query: 605 ---KHCRKKCNCANRG------RCHRLYGACLCDPGLYGRFCHLTCPPWAFGP------G 649
+ C +C+C RG C G C C P + G+ C +C FG G
Sbjct: 768 SNPEGC-TRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFG 825
Query: 650 C-SEECQCVQPHTQSCDKRDGSCSCKAGFRGERC 682
C S C QSC+ R G C C+ +G C
Sbjct: 826 CRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
Score = 78.2 bits (191), Expect = 6e-14
Identities = 85/320 (26%), Positives = 104/320 (32%), Gaps = 59/320 (18%)
Query: 1206 CPPGRYGPGCEQLCGCLNGGSCDAA----TGACRCPTG-FLGTDCNLTCPQGRFG----- 1255
CP +G GC L C D T R P G +L D L P+ +
Sbjct: 1334 CP---HGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVPENVYSFGYLR 1390
Query: 1256 -----PNCTHVCGCG-QGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN 1309
+ + C QG P + + C A + + F C C
Sbjct: 1391 EEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASL--------SLFYNNGARPCGCHE 1442
Query: 1310 ----GGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC 1365
G C G C C GR C C G +G C C C+ TG C C
Sbjct: 1443 VGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRPCDC-GARLCDELTGQCIC 1500
Query: 1366 GPGFYGQACEHPCPPGFHGAGCQGLCWCQH------------GAPCDPISGRCLCPAGFH 1413
P C P F GC L C+ CD SG+C C
Sbjct: 1501 PPRTIPPDCLLCQPQTF---GCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVT 1557
Query: 1414 GHFCERGCEPGSFGEGCHQRCDCD--GGAP--CDPVTGLCLCPPGRSGATCNLDCRRGQF 1469
G C+ C PG G + CDC G AP CDP+TG C C G C+ C G F
Sbjct: 1558 GRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD-QCSLGTF 1615
Query: 1470 -----GPSCTLHCDCGGGAD 1484
P C C G +
Sbjct: 1616 SLDAANPKGCTRCFCFGATE 1635
Score = 77.4 bits (189), Expect = 1e-13
Identities = 68/218 (31%), Positives = 78/218 (35%), Gaps = 29/218 (13%)
Query: 1167 FGEDCAQMCQCP---GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG-PGCEQLCGCL 1222
F + A+ C C P C P G C C A G C RC G +G P C C C
Sbjct: 1430 FYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRP-CDC- 1486
Query: 1223 NGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGC------GQG------AAC 1270
CD TG C CP + DC L PQ FG C + GC G G C
Sbjct: 1487 GARLCDELTGQCICPPRTIPPDCLLCQPQ-TFG--CHPLVGCEECNCSGPGIQELTDPTC 1543
Query: 1271 DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG----GLCHASNGSCSCGLGW 1326
D +G C C P G RC+ C G C C G+C G C C
Sbjct: 1544 DTDSGQCKCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENV 1602
Query: 1327 TGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCR 1364
G C+ C G + C C AT CR
Sbjct: 1603 QGPKCD-QCSLGTFSLDAANPKGC-TRCFCFGATERCR 1638
Score = 67.4 bits (163), Expect = 1e-10
Identities = 45/132 (34%), Positives = 54/132 (40%), Gaps = 17/132 (12%)
Query: 1391 CWCQH----GAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVT 1446
C C G C+P G+C C A G C R C G +G + CDC G CD +T
Sbjct: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC-GARLCDELT 1495
Query: 1447 GLCLCPPGRSGATCNLDCRRGQFGPSCTL---HCDCGGGA-------DCDPVSGQCHCVD 1496
G C+CPP C L C+ FG + C+C G CD SGQC C
Sbjct: 1496 GQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
Query: 1497 GYMGPTCREGGP 1508
G C P
Sbjct: 1555 NVTGRRCDTCSP 1566
Score = 60.5 bits (145), Expect = 1e-08
Identities = 47/152 (30%), Positives = 58/152 (38%), Gaps = 28/152 (18%)
Query: 511 CLDDSFGHDCSL---------TCDDCRNGGTCLLGLDG-CDCPEGWTGLICNETCPPDTF 560
C G DCS C C G L G C CP C C P TF
Sbjct: 1459 CHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCL-LCQPQTF 1517
Query: 561 GKN----CSFSCSCQNGG-------TCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRK 609
G + C C+C G TCD+ +G C+C P V+G C D C G++G +
Sbjct: 1518 GCHPLVGCE-ECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC-DTCSPGFHGYPRCR 1575
Query: 610 KCNCANRGR----CHRLYGACLCDPGLYGRFC 637
C+C G C L G C C + G C
Sbjct: 1576 PCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC 1607
Score = 57.8 bits (138), Expect = 8e-08
Identities = 92/365 (25%), Positives = 116/365 (31%), Gaps = 89/365 (24%)
Query: 268 CECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRI 327
C C Y+ G +C+ ECA G + G L C CH +
Sbjct: 1831 CLCPASYR----GDSCQ---ECAPGFYRDVKG-LFLGRCVPCQCHGHSD----------- 1871
Query: 328 EMEIVNSCEANNGGCSHGCSHTSAGPLCT-CPRGYELDTDQRTCIDVDDCADSPCCQQVC 386
C +G C C H + G C C G+ D + C PC V
Sbjct: 1872 ------RCLPGSGVCVD-CQHNTEGAHCERCQAGFVSSRDDPSA----PCVSCPCPLSVP 1920
Query: 387 TNN--------PGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQ-CS 437
+NN G +C C GY G CE CA G + L S Q C
Sbjct: 1921 SNNFAEGCVLRGGRTQCLCKPGYA----GASCE---RCAPGFFG---NPLVLGSSCQPCD 1970
Query: 438 CEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDEL--PQLFQD-------- 487
C + C PL L H + E+ P + +
Sbjct: 1971 CSGNGDPNLLFSDCDPLTGACRGC---------LRHTTGPRCEICAPGFYGNALLPGNCT 2021
Query: 488 --DDVGADEEEAELRGEHTLTEKFV-------CLDDSFGHDCSLTCDDCR-----NGGTC 533
D E + H L + V C + FG D C C G C
Sbjct: 2022 RCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSEC 2081
Query: 534 LLGLDGCDCPEGWTGLICNETCPPDTFG---KNCSFSCSCQNGGTCDSVTGACRCPPGVS 590
C C G G C E C P +G + C C C GG CD TG C CPPG+S
Sbjct: 2082 HPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQGCR-RCQCP-GGRCDPHTGRCNCPPGLS 2138
Query: 591 GTNCE 595
G C+
Sbjct: 2139 GERCD 2143
Score = 51.6 bits (122), Expect = 6e-06
Identities = 39/132 (29%), Positives = 48/132 (36%), Gaps = 25/132 (18%)
Query: 510 VCLDDSFGHDCSLTCDDCRNGG---------TCLLGLDGCDCPEGWTGLICNETCPPDTF 560
+C +FG + C++C G TC C C TG C +TC P
Sbjct: 1511 LCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC-DTCSPGFH 1569
Query: 561 GKNCSFSCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANR 616
G C C GT CD +TG C C V G C D C G + + AN
Sbjct: 1570 GYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-DQCSLGTF------SLDAANP 1622
Query: 617 GRCHRLYGACLC 628
C R C C
Sbjct: 1623 KGCTR----CFC 1630
Score = 51.2 bits (121), Expect = 8e-06
Identities = 83/338 (24%), Positives = 113/338 (33%), Gaps = 73/338 (21%)
Query: 136 GGRCVPGSAQPCHCPPGFQGPRCQYDVDEC-----RTHNGGCQHRCVNTPGSYLCECKPG 190
G + + + C CP ++G CQ EC R G RCV C+C
Sbjct: 1820 GQGALASNVELCLCPASYRGDSCQ----ECAPGFYRDVKGLFLGRCVP------CQC--- 1866
Query: 191 FRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED--GRHCVR-RSP 247
H S CL G+G C C T H +C+ GF D CV P
Sbjct: 1867 ---HGHSDRCLP------GSGVCV-DCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCP 1916
Query: 248 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSF 307
+ + + C + G +C C GY G +CE CA G + +
Sbjct: 1917 LSVPSNNFAEGCVLRGGRTQCLCKPGYA----GASCE---RCAPGF--FGNPLVLGSSCQ 1967
Query: 308 KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC-TCPRGYELDTD 366
C C + + + C+ G C GC + GP C C G+ +
Sbjct: 1968 PCDCSGNGDPNL-----------LFSDCDPLTGAC-RGCLRHTTGPRCEICAPGFYGNAL 2015
Query: 367 QRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGY-----------RLSADGCGCEDVDE 415
DC +PC + C +P C C AG DGCG
Sbjct: 2016 LPGNCTRCDC--TPCGTEAC--DPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCA 2071
Query: 416 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSP 453
C + G E H S QC C G + R C+P
Sbjct: 2072 CGPAAEGSECH----PQSGQCHCRPG-TMGPQCRECAP 2104
Score = 44.7 bits (104), Expect = 7e-04
Identities = 77/311 (24%), Positives = 103/311 (33%), Gaps = 79/311 (25%)
Query: 110 CCRGWMQQPDEEGCLSAECSASLCF-HGGRCVPGSAQPCHCPPGFQG---PRCQYDVDEC 165
C G+ + D +G C C H RC+PGS C +G RCQ
Sbjct: 1845 CAPGFYR--DVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSS 1902
Query: 166 R---------------THNGGCQHRCVNTPGSYLCECKPGFR-----------------L 193
R + CV G C CKPG+ L
Sbjct: 1903 RDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVL 1962
Query: 194 HTDSRTC---------LAINSCALGNGGCQHHCVQLTITRHRCQ-CRPGFQ----LQEDG 239
+ + C L + C G C+ C++ T T RC+ C PGF L +
Sbjct: 1963 GSSCQPCDCSGNGDPNLLFSDCDPLTGACR-GCLRHT-TGPRCEICAPGFYGNALLPGNC 2020
Query: 240 RHC----VRRSPCANRNGSCMHRCQVV-RGLARC-ECHVGYQLAADGKACEDVDECAAGL 293
C C +G C+ + V R RC E H G+ DG C CA G
Sbjct: 2021 TRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGF----DG--CGGCRPCACGP 2074
Query: 294 AQCAHGCLNTQGSFKCVCHAGYELGADGRQC----YRIEMEIVNSCEANNGGCSHGCSHT 349
A C G +C C G +G R+C + + + C+ G C HT
Sbjct: 2075 AAEGSECHPQSG--QCHCRPG-TMGPQCRECAPGYWGLPEQGCRRCQCPGGRCD---PHT 2128
Query: 350 SAGPLCTCPRG 360
C CP G
Sbjct: 2129 GR---CNCPPG 2136
Score = 40.4 bits (93), Expect = 0.013
Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 8/49 (16%)
Query: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRC 158
C G+ P E+GC +C GGRC P + + C+CPPG G RC
Sbjct: 2102 CAPGYWGLP-EQGCRRCQCP------GGRCDPHTGR-CNCPPGLSGERC 2142
Score = 31.2 bits (69), Expect = 8.1
Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 14/71 (19%)
Query: 1448 LCLCPPGRSGATCNLDCR-------RGQFGPSCTLHCDCGGGAD-CDPVSGQC----HCV 1495
LCLCP G +C +C +G F C + C C G +D C P SG C H
Sbjct: 1830 LCLCPASYRGDSCQ-ECAPGFYRDVKGLFLGRC-VPCQCHGHSDRCLPGSGVCVDCQHNT 1887
Query: 1496 DGYMGPTCREG 1506
+G C+ G
Sbjct: 1888 EGAHCERCQAG 1898
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 221 bits (562), Expect = 6e-57
Identities = 209/718 (29%), Positives = 265/718 (36%), Gaps = 161/718 (22%)
Query: 860 CDTGHWGPDCSHPC---NCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR 916
CD ++ C+ C N GH +CD G C G++G C++ C+Q
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQY-GNKACMDGWMGKECKEAV--------CKQG 248
Query: 917 CQCQHGAACDHVSGACTCPAGWRGTFCEHACP-AGFFGLDCRS--ACNCT---AGAACD- 969
C HG V G C C GW+G FC+ P G C CNC G CD
Sbjct: 249 CNLLHGGCT--VPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDK 306
Query: 970 ----------AVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQ---ACA---CFNGASCDP 1013
NG A RC TCP G NC + AC C NG SC
Sbjct: 307 DLNYCGSHHPCTNGGTCINAEPDQYRC--TCPDGYSGRNCEKAEHACTSNPCANGGSCHE 364
Query: 1014 VHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC-DPVSG-HCACPEGWAG 1069
V +CHC GW GP+C L D C S C GGTC D V G C CPE W G
Sbjct: 365 VPSGFECHCPSGWSGPTC------ALDIDECA-SNPCAAGGTCVDQVDGFECICPEQWVG 417
Query: 1070 LACEKECLPRDVRAGCRHSGGC---LNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGE 1126
C+ + D R C+H G C +NG +C+CP G+ G C+ +
Sbjct: 418 ATCQLDV--NDCRGQCQHGGTCKDLVNG-------YQCVCPRGFGGRHCELE------RD 462
Query: 1127 ACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCE---QACPPGSF--GEDCAQM----- 1174
CA C G C + C CP GF+G CE C P G C +
Sbjct: 463 ECAS-SPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 521
Query: 1175 CQCPGE--NPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG 1232
C CP + C C A C PG G +CG G C + G
Sbjct: 522 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCG--PHGRCVSQPG 579
Query: 1233 ---ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC-DPVTG-TCLCPPGRAGVR 1287
+C C +GF GT C+ P C G C D V C CP G G
Sbjct: 580 GNFSCICDSGFTGTYCHENIDDCLGQP-------CRNGGTCIDEVDAFRCFCPSGWEGEL 632
Query: 1288 CERGCPQNRFGVGCEHTC---SCRNGGLCH--ASNGSCSCGLGWTGRHC---ELACPPGR 1339
C+ + C C + G C+ ++ C+C GW G+ C E C
Sbjct: 633 CDTN----------PNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCD--- 679
Query: 1340 YGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGC----QGLCW--- 1392
+C N TC + T RC CPPG+ G+ C C
Sbjct: 680 -------AYTCSNGGTCYDSGDTFRCA-----------CPPGWKGSTCAVAKNSSCLPNP 721
Query: 1393 CQHGAPC--DPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGL-C 1449
C +G C S C+C G+ G C C+ +GG D V C
Sbjct: 722 CVNGGTCVGSGASFSCICRDGWEGRTCTHNT------NDCNPLPCYNGGICVDGVNWFRC 775
Query: 1450 LCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADC-DPVSG-QCHCVDGYMGPTCRE 1505
C PG +G C ++ Q P C GA C D ++G +C C G GP C+E
Sbjct: 776 ECAPGFAGPDCRINIDECQSSP-------CAYGATCVDEINGYRCSCPPGRAGPRCQE 826
Score = 192 bits (488), Expect = 2e-48
Identities = 220/823 (26%), Positives = 282/823 (34%), Gaps = 216/823 (26%)
Query: 598 CPKGYYGKHCRKKCNCAN------------------------------RGRCHRLYGACL 627
C + YY C K C N + C+ L+G C
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCT 257
Query: 628 ------CDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGF---- 677
C G GRFC C P+ PGC CV+P +C+ G C
Sbjct: 258 VPGECRCSYGWQGRFCD-ECVPY---PGCVHG-SCVEPWQCNCETNWGGLLCDKDLNYCG 312
Query: 678 ------RGERC--------QAECELGYFGPGCWQ---ACT---CPVGVACDSVSGECGKR 717
G C + C GY G C + ACT C G +C V
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECH 372
Query: 718 CPAGFQGEDCG---QECPVGTFGVNCSSSCSCGGAPCHGVTG-QCRCPPGRTGEDCEADC 773
CP+G+ G C EC S+ C+ GG V G +C CP G C+ D
Sbjct: 373 CPSGWSGPTCALDIDEC--------ASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDV 424
Query: 774 PEGRWGL-----------GCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV------ 816
+ R G Q +CP C+ E C P G C+D+
Sbjct: 425 NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHC 484
Query: 817 -CPAGWYGPSCQTRCS------CANDGHCHPATG--HCSCAPGWTGFSCQ--------RA 859
CP G+ GP C+ C N C+ G +C+C + G +C A
Sbjct: 485 HCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGA 544
Query: 860 C--------DTGHWGPDCSHPCNCSAGHGSCDAISG---LCLCEAGYVGPRCEQQCPQGH 908
C D G P + C HG C + G C+C++G+ G C +
Sbjct: 545 CRVIDGCGSDAGPGMPGTAASGVCGP-HGRCVSQPGGNFSCICDSGFTGTYCHENIDDCL 603
Query: 909 FGPGCEQRCQCQHGAAC-DHVSG-ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA 966
P C++G C D V C CP+GW G C+ P C S C
Sbjct: 604 GQP-------CRNGGTCIDEVDAFRCFCPSGWEGELCD-TNPNDCLPDPCHSRGRC---- 651
Query: 967 ACDAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPG 1023
D VN C C G +G C H+ C A C NG +C +C C PG
Sbjct: 652 -YDLVNDFYCACDDGWKGKTC------HSREFQC-DAYTCSNGGTCYDSGDTFRCACPPG 703
Query: 1024 WMGPSCLQACPAGLYGDNCRHSCL---CQNGGTC--DPVSGHCACPEGWAGLAC---EKE 1075
W G +C A SCL C NGGTC S C C +GW G C +
Sbjct: 704 WKGSTCAVA---------KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTND 754
Query: 1076 CLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
C P C NGG+C RC C G+ G C+ + C Q
Sbjct: 755 CNPLP----------CYNGGICVDGVNWFRCECAPGFAGPDCRINI------DEC-QSSP 797
Query: 1134 CPPGAAC-HHVTG-ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC 1191
C GA C + G C CPPG G C++ FG C P H ++
Sbjct: 798 CAYGATCVDEINGYRCSCPPGRAGPRCQEVI---GFGRSCWSR-----GTPFPHGSSWVE 849
Query: 1192 SCAAGYHGPSCQQRCPPGRYGPGCEQL-CG---CLNGGSCDAATGACRCPTGFLGTDCNL 1247
C SC RC GR C ++ CG CL G +A + C LG C
Sbjct: 850 DC------NSC--RCLDGR--RDCSKVWCGWKPCLLAGQPEALSAQCP-----LGQRCLE 894
Query: 1248 TCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCER 1290
P P C CG A +P + CL G C R
Sbjct: 895 KAPGQCLRPPCEAWGECG---AEEPPSTPCLPRSGHLDNNCAR 934
Score = 187 bits (475), Expect = 7e-47
Identities = 214/814 (26%), Positives = 287/814 (35%), Gaps = 198/814 (24%)
Query: 336 EANNGGCSHGCSHTSAGPL----CTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPG 391
E C GC+ G C C G++ R C D+C P C P
Sbjct: 239 ECKEAVCKQGCNLLHGGCTVPGECRCSYGWQ----GRFC---DECVPYPGCVHGSCVEP- 290
Query: 392 GYECGCYAGYRLSADGCGCE-DVDECASSRGGCEHHCTNLA-------GSFQCSCEAGYR 443
++C C + G C+ D++ C G H CTN ++C+C GY
Sbjct: 291 -WQCNCETNW----GGLLCDKDLNYC-----GSHHPCTNGGTCINAEPDQYRCTCPDGY- 339
Query: 444 LHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEH 503
R C E P + E+P F+
Sbjct: 340 ---SGRNCEKAEHACTS--------NPCANGGSCH-EVPSGFECH--------------- 372
Query: 504 TLTEKFVCLDDSFGHDCSLTCDDCRN-----GGTCLLGLDG--CDCPEGWTGLICNETCP 556
C G C+L D+C + GGTC+ +DG C CPE W G C +
Sbjct: 373 -------CPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATC-QLDV 424
Query: 557 PDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANR 616
D G+ CQ+GGTC + +C CP+G+ G+HC + +
Sbjct: 425 NDCRGQ-------CQHGGTCKDLVNGYQCV-----------CPRGFGGRHCELERDECAS 466
Query: 617 GRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP----HTQSCDKRDGS-- 670
CH LC+ G CH CP GP C + +P + C +G
Sbjct: 467 SPCH---SGGLCEDLADGFHCH--CPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 521
Query: 671 CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQE 730
C+C F G+ C E CP G AC + G CG G G
Sbjct: 522 CACPDDFGGKNCSVPRE------------PCPGG-ACRVIDG-CGSDAGPGMPGTAASGV 567
Query: 731 C---------PVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLG 781
C P G F C S + G CH C P R G C + R
Sbjct: 568 CGPHGRCVSQPGGNFSCICDSGFT--GTYCHENIDDCLGQPCRNGGTCIDEVDAFRC--- 622
Query: 782 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDV-------CPAGWYGPSCQTR----- 829
CP+ CD CL P RC D+ C GW G +C +R
Sbjct: 623 ---FCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCD 679
Query: 830 -CSCANDGHCHPA--TGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAIS 886
+C+N G C+ + T C+C PGW G +C A ++ C + C G G+ S
Sbjct: 680 AYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTC-VGSGA----S 734
Query: 887 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAAC-DHVSG-ACTCPAGWRGTFCE 944
C+C G+ G C H C C +G C D V+ C C G+ G C
Sbjct: 735 FSCICRDGWEGRTCT------HNTNDCNP-LPCYNGGICVDGVNWFRCECAPGFAGPDCR 787
Query: 945 HACPAGFFGLDCRSACNCTAGAAC-DAVNG-SCLCPAGRRGPRCAETCPAHTYGHNC-SQ 1001
+D + C GA C D +NG C CP GR GPRC E +G +C S+
Sbjct: 788 -------INIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI---GFGRSCWSR 837
Query: 1002 ACACFNGA-------SCDPVHGQCHCAPGWMG--PSCLQACPAGLYGDNCRHSCLCQNGG 1052
+G+ SC + G+ C+ W G P L P L S C G
Sbjct: 838 GTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEAL-------SAQCPLGQ 890
Query: 1053 TC-DPVSGHCACP--EGWAGLACEK----ECLPR 1079
C + G C P E W E+ CLPR
Sbjct: 891 RCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPR 924
Score = 177 bits (450), Expect = 5e-44
Identities = 218/806 (27%), Positives = 298/806 (36%), Gaps = 180/806 (22%)
Query: 181 GSYLCE------CKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQ 234
G Y C+ C G+ + + + + C L +GGC C+C G+Q
Sbjct: 219 GHYTCDQYGNKACMDGW-MGKECKEAVCKQGCNLLHGGCT--------VPGECRCSYGWQ 269
Query: 235 LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGL 293
GR C C G C+H V CE + G G C+ D++ C +
Sbjct: 270 ----GRFC---DECVPYPG-CVHGSCVEPWQCNCETNWG------GLLCDKDLNYCGSH- 314
Query: 294 AQCAHG--CLNTQ-GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTS 350
C +G C+N + ++C C GY GR C + E ++ AN G C
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTSNPCANGGSCHE----VP 366
Query: 351 AGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADGCG 409
+G C CP G+ T +D+D+CA +PC C + G+EC C + G
Sbjct: 367 SGFECHCPSGWSGPT---CALDIDECASNPCAAGGTCVDQVDGFECICPEQWV----GAT 419
Query: 410 CE-DVDECASSRGGCEHH--CTNLAGSFQCSCEAGY-----RLHEDRRGCSP-----LEE 456
C+ DV++C RG C+H C +L +QC C G+ L D SP L E
Sbjct: 420 CQLDVNDC---RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCE 476
Query: 457 PMVD-LDGELP--FVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLD 513
+ D P F PL + V L + L G++ C D
Sbjct: 477 DLADGFHCHCPQGFSGPLCEVDV------DLCEPSPCRNGARCYNLEGDYYCA----CPD 526
Query: 514 DSFGHDCSLTCDDCRNGGTCLLGLDGC--DCPEGWTGLICNETCPPD---TFGKNCSFSC 568
D G +CS+ + C GG C + +DGC D G G + C P +FSC
Sbjct: 527 DFGGKNCSVPREPC-PGGACRV-IDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSC 584
Query: 569 SCQNGGT---CDSVTGACRCPPGVSGTNCEDG-------CPKGYYGKHCRKKCN------ 612
C +G T C C P +G C D CP G+ G+ C N
Sbjct: 585 ICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDP 644
Query: 613 CANRGRCHRLYG--ACLCDPGLYGRFCH---LTCPPWAFGPGCSEECQCVQPHTQSCDKR 667
C +RGRC+ L C CD G G+ CH C + CS C D
Sbjct: 645 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYT----CSNGGTCY-------DSG 693
Query: 668 DG-SCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGED 726
D C+C G++G C C TC VG S C C G++G
Sbjct: 694 DTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTC-VG---SGASFSC--ICRDGWEGRT 747
Query: 727 CGQECPVGTFGVNCSSSCSC--GGAPCHGVTG-QCRCPPGRTGEDCEADCPEGRWGLGCQ 783
C T N + C GG GV +C C PG G DC + E CQ
Sbjct: 748 C-------THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDE------CQ 794
Query: 784 EICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSCQTR-------CSCAN 834
C + A C E C C PG G RCQ+V +G SC +R S
Sbjct: 795 S--SPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI---GFGRSCWSRGTPFPHGSSWVE 849
Query: 835 D-GHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEA 893
D C G C+ W G+ PC + G +A+S C
Sbjct: 850 DCNSCRCLDGRRDCSKVWCGWK----------------PCLLA---GQPEALSAQC---- 886
Query: 894 GYVGPRCEQQCPQGHFGPGCEQRCQC 919
+G RC ++ P P CE +C
Sbjct: 887 -PLGQRCLEKAPGQCLRPPCEAWGEC 911
Score = 165 bits (417), Expect = 4e-40
Identities = 185/674 (27%), Positives = 253/674 (37%), Gaps = 159/674 (23%)
Query: 123 CLSAE--CSASLCFHGGRC--VPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVN 178
C AE C+++ C +GG C VP + CHCP G+ GP C D+DEC ++ CV+
Sbjct: 344 CEKAEHACTSNPCANGGSCHEVPSGFE-CHCPSGWSGPTCALDIDECASNPCAAGGTCVD 402
Query: 179 TPGSYLCECKPGFRLHTDSRTC-LAINSCALGNGGCQH--HCVQLTITRHRCQCRPGFQL 235
+ C C + TC L +N C G CQH C L + ++C C GF
Sbjct: 403 QVDGFECICPEQW----VGATCQLDVNDC---RGQCQHGGTCKDL-VNGYQCVCPRGF-- 452
Query: 236 QEDGRHC-VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGL 293
GRHC + R CA+ C+ + C C G+ G CE DVD C
Sbjct: 453 --GGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGF----SGPLCEVDVDLCEPSP 506
Query: 294 AQCAHGCLNTQGSFKCVC---HAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTS 350
+ C N +G + C C G C +++ C ++ G G T+
Sbjct: 507 CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAG---PGMPGTA 563
Query: 351 AGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGG-YECGCYAGYRLSADGCG 409
A +C P G C + PGG + C C +G+ G
Sbjct: 564 ASGVCG-PHGR------------------------CVSQPGGNFSCICDSGF----TGTY 594
Query: 410 C-EDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFV 468
C E++D+C C + +F+C C +G+ +GEL
Sbjct: 595 CHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW-------------------EGELCDT 635
Query: 469 RP---LPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD 525
P LP + L D D+ +G+ + +F C D++ TC
Sbjct: 636 NPNDCLPDPCHSRGRCYDLVNDFYCACDD---GWKGKTCHSREFQC--DAY------TCS 684
Query: 526 DCRNGGTCLLGLD--GCDCPEGWTGLIC----NETCPPD-------TFGKNCSFSCSCQN 572
NGGTC D C CP GW G C N +C P+ G SFSC C++
Sbjct: 685 ---NGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRD 741
Query: 573 ---GGTCDSVTGACRCPPGVSGTNCEDG-------CPKGYYGKHCRKKCNCANRGRCHRL 622
G TC T C P +G C DG C G+ G CR + C
Sbjct: 742 GWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPC--A 799
Query: 623 YGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC----QCVQ-----PHTQSCDKRDGSCSC 673
YGA C + G C +CPP GP C E C PH S + SC C
Sbjct: 800 YGA-TCVDEINGYRC--SCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC 856
Query: 674 KAGFRGERCQAECELGYFGPGCWQAC-----------TCPVGVAC-DSVSGECGKRCPAG 721
G R +C + G W+ C CP+G C + G+C R P
Sbjct: 857 LDGRR------DCSKVWCG---WKPCLLAGQPEALSAQCPLGQRCLEKAPGQC-LRPPCE 906
Query: 722 FQGEDCGQECPVGT 735
GE CG E P T
Sbjct: 907 AWGE-CGAEEPPST 919
Score = 58.9 bits (141), Expect = 4e-08
Identities = 54/200 (27%), Positives = 70/200 (35%), Gaps = 37/200 (18%)
Query: 1335 CPPGRYGAACHLECSCHNNS----TCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGL 1390
C Y A C+ C N+ TC+ G C G+ G+ C+ A C+
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQY-GNKACMDGWMGKECKE--------AVCKQG 248
Query: 1391 CWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCL 1450
C HG P G C C G+ G FC+ C C G+ +P C
Sbjct: 249 CNLLHGGCTVP--GECRCSYGWQGRFCDE----------CVPYPGCVHGSCVEPWQ--CN 294
Query: 1451 CPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADC---DPVSGQCHCVDGYMGPTCREGG 1507
C G C+ D C H C G C +P +C C DGY G C E
Sbjct: 295 CETNWGGLLCDKDLNY------CGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC-EKA 347
Query: 1508 PLRLPENPSLAQGSAGTLPA 1527
NP GS +P+
Sbjct: 348 EHACTSNPCANGGSCHEVPS 367
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 215 bits (548), Expect = 2e-55
Identities = 133/358 (37%), Positives = 179/358 (50%), Gaps = 43/358 (12%)
Query: 133 CFHGGRCVP-----GSAQPCHCPPGFQ----GPRCQYDVDECRTHNGGCQ--HRCVNTPG 181
C GG C G C C G+Q G C+ DV+EC T + C+ C+NT G
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCE-DVNECITGSHSCRLGESCINTVG 238
Query: 182 SYLCE----CKPGFRLHTDSRTCLAINSCALGNGGCQHHCV-QLTITRHRC----QCRPG 232
S+ C+ C G+ L T+ +C I+ C G C + Q T+ RC QC+ G
Sbjct: 239 SFRCQRDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG 297
Query: 233 FQLQEDGRHCVRRSPCANRNGSCM--HRCQVVRGLARCE-----CHVGYQLAADGKACED 285
F +Q+ +C+ + C + + C H C G C+ C GY L +G C D
Sbjct: 298 F-IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD 356
Query: 286 VDECAAGLAQCA--HGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGG-C 342
VDECA C H C+N+ GSF+C C GY R C VN C+ G C
Sbjct: 357 VDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-----VNECQRYPGRLC 411
Query: 343 SHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYR 402
H C +T LC+C G+ L D R+C D+++C+ SPC Q+ C N G Y+C C GY+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQE-CANVYGSYQCYCRRGYQ 470
Query: 403 LS-ADGCGCEDVDECASSRGG--CEHHCTNLAGSFQCSC-EAGYRLHEDRRGCSPLEE 456
LS DG CED+DECA GG C + C N+ GSFQCSC +GYRL + R C ++E
Sbjct: 471 LSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDE 528
Score = 180 bits (456), Expect = 1e-44
Identities = 112/309 (36%), Positives = 146/309 (47%), Gaps = 35/309 (11%)
Query: 161 DVDECRT--HNGGCQHRCVNTPGSYLC----ECKPGFRLHTDSRTCLAINSCALGNGGCQ 214
D+DEC + HN C NT GS+ C +CK GF + C+ IN C + C
Sbjct: 262 DIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQDALGNCIDINECLSISAPCP 320
Query: 215 --HHCVQLTITRHRCQ-----CRPGFQLQEDGRHCVRRSPCANRNGSCM--HRCQVVRGL 265
H C+ T + CQ C G+ L E+G CV CA C HRC G
Sbjct: 321 IGHTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS 379
Query: 266 ARCECHVGYQLAADGKACEDVDECAAGLAQ-CAHGCLNTQGSFKCVCHAGYELGADGRQC 324
RCEC GY + C DV+EC + C H C NT GS+ C C G+ L DGR C
Sbjct: 380 FRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Query: 325 YRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYEL-DTDQRTCIDVDDCA---DSP 380
E +N C ++ CS C++ C C RGY+L D D TC D+D+CA
Sbjct: 440 -----EDINECSSSP--CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGH 492
Query: 381 CCQQVCTNNPGGYECGC-YAGYRLSADGCGCEDVDECASSRGGC--EHHCTNLAGSFQC- 436
C C N PG ++C C +GYRL+ +G C+D+DEC + C C N+ G F+C
Sbjct: 493 ICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Query: 437 --SCEAGYR 443
C YR
Sbjct: 553 AFECPENYR 561
Score = 143 bits (360), Expect = 1e-33
Identities = 100/284 (35%), Positives = 135/284 (47%), Gaps = 39/284 (13%)
Query: 105 RTVLRCCRGWMQQP-----DEEGCLSAECSASLCFHGGRCV-PGSAQPC-----HCPPGF 153
R L+C G++Q D CLS C G C+ + C +C G+
Sbjct: 289 RPKLQCKSGFIQDALGNCIDINECLSISAP---CPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 154 ----QGPRCQYDVDECRTHNGGCQ--HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCA 207
+G RC DVDEC C HRCVN+PGS+ CECK G+ SR C+ +N C
Sbjct: 346 HLNEEGTRC-VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQ 404
Query: 208 LGNGG-CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLA 266
G C H C + T+ + C C GF+L DGR C + C+ + C C V G
Sbjct: 405 RYPGRLCGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSY 461
Query: 267 RCECHVGYQLA-ADGKACEDVDECA--AGLAQCAHGCLNTQGSFKCVC-HAGYELGADGR 322
+C C GYQL+ DG CED+DECA G C++ C+N GSF+C C +GY L +GR
Sbjct: 462 QCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGR 521
Query: 323 QCYRIEMEI--VNSCEANNGGCSHGCSHTSAGPLC---TCPRGY 361
C I+ + +++C N C + G C CP Y
Sbjct: 522 NCQDIDECVTGIHNCSIN-----ETCFNIQGGFRCLAFECPENY 560
Score = 92.8 bits (229), Expect = 2e-18
Identities = 138/573 (24%), Positives = 192/573 (33%), Gaps = 136/573 (23%)
Query: 265 LARCECHVGYQLAADGKAC-----EDVDECAAGLAQCAHGCL-----NTQG-SFKCVCHA 313
L C G LA + C ++ A + +C H CL QG S +
Sbjct: 73 LEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMV 132
Query: 314 GYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDV 373
GY+ G R C V S E + G L + E++ +Q
Sbjct: 133 GYQCGQVFRAC------CVKSQETGD---------LDVGGLQETDKIIEVEEEQEDPYLN 177
Query: 374 DDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCE--HHCTNLA 431
D C C+Q C + C C+ GY+L +DG CEDV+EC + C C N
Sbjct: 178 DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 432 GSFQC----SCEAGYRLHEDRRGCSPLEEPMVDLDGELP-FV--------RPLPHI---- 474
GSF+C SC GY L ED C ++E + LP F+ R P +
Sbjct: 238 GSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 475 AVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNG---- 530
+QD L ++ + + HT C++ + C +C G
Sbjct: 297 GFIQDALGNCIDINECLSISAPCPI--GHT------CINTEGSYTCQKNVPNCGRGYHLN 348
Query: 531 --GTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNC-----SFSCSCQNGGTCDSVTGAC 583
GT + +D C P P G C SF C C+ G D ++ C
Sbjct: 349 EEGTRCVDVDECAPP-----------AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Query: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643
V C+ Y G+ C K C G+ LC C +
Sbjct: 398 -----VDVNECQ-----RYPGRLCGHK--------CENTLGSYLCS-------CSVGFRL 432
Query: 644 WAFGPGCSEECQC-VQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCP 702
G C + +C P +Q C GS C C GY +
Sbjct: 433 SVDGRSCEDINECSSSPCSQECANVYGSYQC-----------YCRRGY-------QLSDV 474
Query: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPP 762
GV C+ + EC P G G C C + S CSC +G P
Sbjct: 475 DGVTCEDID-ECA--LPTG--GHICSYRC----INIPGSFQCSCPS------SGYRLAPN 519
Query: 763 GRTGEDCEADCPEGRWGLGCQEICPACQHAARC 795
GR +D + +C G E C Q RC
Sbjct: 520 GRNCQDID-ECVTGIHNCSINETCFNIQGGFRC 551
Score = 60.1 bits (144), Expect = 2e-08
Identities = 124/559 (22%), Positives = 175/559 (31%), Gaps = 120/559 (21%)
Query: 559 TFGKNCSF-------SCSCQNGGTCDSVTGACRCPPGVSGTNCEDGC--PKG-------Y 602
T K+CS C C S C G+S N +D C P G
Sbjct: 45 THQKDCSLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEAT 104
Query: 603 YGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQ 662
+ K C C+C GR + G C+ L + QC Q
Sbjct: 105 FVKRC---CHCCLLGRAAQAQGQS-CEYSLMVGY------------------QCGQVFRA 142
Query: 663 SCDKRDGSCSCKAG------------------FRGERCQA--ECELGYFGPGCWQACTCP 702
C K + G + +RC+ C+ G C+C
Sbjct: 143 CCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCF 202
Query: 703 VG--VACDSVSGECGKRCPAGFQGEDCGQEC--PVGTFGVNCSSSCSCGGAPCHGVTGQC 758
VG + D VS E C G G+ C VG+F C SCG + +T
Sbjct: 203 VGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF--RCQRDSSCGTG--YELTEDN 258
Query: 759 RCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVG---SRCQD 815
C +D + +C G IC + RC P+ C GF+ C D
Sbjct: 259 SC------KDID-ECESGIHNCLPDFICQNTLGSFRCRPK---LQCKSGFIQDALGNCID 308
Query: 816 VCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNC 875
+ C +C N G +C +C R G C C
Sbjct: 309 INECLSISAPCPIGHTCIN------TEGSYTCQKNVP--NCGRGYHLNEEGTRCVDVDEC 360
Query: 876 SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRC----QCQH------GAAC 925
+ C C+ G RCE C G++ G + C +CQ G C
Sbjct: 361 APPAEPCGK-GHRCVNSPGSF--RCE--CKTGYYFDGISRMCVDVNECQRYPGRLCGHKC 415
Query: 926 DHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAGR 981
++ G+ C+C G+R + +C D + C V GS C C G
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSCE------DINECSSSPCSQECANVYGSYQCYCRRGY 469
Query: 982 R-----GPRC--AETCPAHTYGHNCSQACACFNGA-SCDPVHGQCHCAPGWMGPSCLQAC 1033
+ G C + C T GH CS C G+ C AP + C
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 1034 PAGLYGDNCRHSCLCQNGG 1052
G++ + +C GG
Sbjct: 530 VTGIHNCSINETCFNIQGG 548
Score = 56.2 bits (134), Expect = 2e-07
Identities = 126/552 (22%), Positives = 171/552 (30%), Gaps = 112/552 (20%)
Query: 1035 AGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSG----G 1090
AG+ D +C C +G C+ P KEC R V+ C HS
Sbjct: 25 AGVDADVLLEAC-CADGHRMATHQKDCSLPYATES----KEC--RMVQEQCCHSQLEELH 77
Query: 1091 CLNGGLCDPHTGRCLCPAGWTGD-------KCQSPCLRGWFGEACAQRC--SCPPGAACH 1141
C G RC P G +C CL G +A Q C S G C
Sbjct: 78 CATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCG 137
Query: 1142 HVTGACRCPPGFTGS-------GCEQACPPGSFGEDCAQMCQCPGENPACHPATGT---- 1190
V AC TG ++ ED +C G P T
Sbjct: 138 QVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEV 197
Query: 1191 -CSCAAGYH----GPSCQQ--RCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPT-GFLG 1242
CSC GY G SC+ C G + C G SC G+ RC G
Sbjct: 198 VCSCFVGYQLLSDGVSCEDVNECITGSHS--------CRLGESCINTVGSFRCQRDSSCG 249
Query: 1243 TDCNLTCPQGRFGPNCTHVCGCGQGA-------ACDPVTGTCLCPPGRAGVRCERGCPQN 1295
T LT +C + C G C G+ C P ++C+ G Q+
Sbjct: 250 TGYELTEDN-----SCKDIDECESGIHNCLPDFICQNTLGSFRCRPK---LQCKSGFIQD 301
Query: 1296 RFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNST 1355
G +C + C + + C G H + + T
Sbjct: 302 ALG-------NCIDINECLSISAPCPIG---------------------HTCINTEGSYT 333
Query: 1356 CEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGH 1415
C+ CG G++ C A C H P S RC C G++
Sbjct: 334 CQK--NVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 1416 FCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTL 1475
R C + C + G C+ G LC +C++ R G SC
Sbjct: 392 GISRMCVDVN---ECQRYPGRLCGHKCENTLGSYLC-------SCSVGFRLSVDGRSCED 441
Query: 1476 HCDCGG---GADCDPVSG--QCHCVDGYM-----GPTCREGGPLRLPENPSLAQGSAGTL 1525
+C +C V G QC+C GY G TC + LP + +
Sbjct: 442 INECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINI 501
Query: 1526 PASSRPTSRSGG 1537
P S + + S G
Sbjct: 502 PGSFQCSCPSSG 513
Score = 53.5 bits (127), Expect = 2e-06
Identities = 130/588 (22%), Positives = 167/588 (28%), Gaps = 149/588 (25%)
Query: 830 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLC 889
C + CH CA TG S D C+ HG ++
Sbjct: 61 CRMVQEQCCHSQLEELHCA---TGISLANEQD------------RCATPHGDNASL---- 101
Query: 890 LCEAGYVGPRCEQQCPQGHFGPGCEQRCQ--CQHGAACDHVSGACTCPAGWRGTF----- 942
EA +V RC C G Q C+ G C V AC + G
Sbjct: 102 --EATFV-KRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGL 158
Query: 943 --------CEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRR----GPRCAETC 990
E + CR C C C G + G C +
Sbjct: 159 QETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVN 218
Query: 991 PAHTYGHNCSQACACFNGASCDPVHGQCHCAPGW---MGPSC--LQACPAGLYGDNCRHS 1045
T H+C +C N C G+ SC + C +G++ NC
Sbjct: 219 ECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIH--NCLPD 276
Query: 1046 CLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCL 1105
+CQN G C L C K +D C CL+ P C+
Sbjct: 277 FICQN------TLGSFRCR---PKLQC-KSGFIQDALGNCIDINECLSISAPCPIGHTCI 326
Query: 1106 CPAG-WTGDKCQSPCLRGWF----GEACAQRCSC-PPGAACHHVTGACRCPPGFTGSGCE 1159
G +T K C RG+ G C C PP C G G
Sbjct: 327 NTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC--------------GKGHR 372
Query: 1160 QACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLC 1219
PGSF C C GY+ + C C++
Sbjct: 373 CVNSPGSF----------------------RCECKTGYYFDGISRMCVDVN---ECQRYP 407
Query: 1220 GCLNGGSCDAATGA--CRCPTGFL----GTDCN--LTCPQGRFGPNCTHV-----CGCGQ 1266
G L G C+ G+ C C GF G C C C +V C C +
Sbjct: 408 GRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRR 467
Query: 1267 GAACDPVTGT-------CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGS 1319
G V G C P G G C C + CSC + G A N
Sbjct: 468 GYQLSDVDGVTCEDIDECALPTG--GHICSYRC----INIPGSFQCSCPSSGYRLAPN-- 519
Query: 1320 CSCGLGWTGRHCE--LACPPGRYGAACHLECSCHNNSTCEPATGTCRC 1365
GR+C+ C G + +C N TC G RC
Sbjct: 520 --------GRNCQDIDECVTGIH--------NCSINETCFNIQGGFRC 551
Score = 52.8 bits (125), Expect = 3e-06
Identities = 107/483 (22%), Positives = 154/483 (31%), Gaps = 119/483 (24%)
Query: 525 DDCRNGGTCLLGLDG------CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDS 578
D CR GG C C C G+ L +C + + + S SC+ G +C +
Sbjct: 178 DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC--EDVNECITGSHSCRLGESCIN 235
Query: 579 VTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCH 638
G+ RC + C GY + +C + C CL D
Sbjct: 236 TVGSFRC-------QRDSSCGTGY---ELTEDNSCKDIDECESGIHNCLPDFICQNTLGS 285
Query: 639 LTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQ- 697
C P CK+GF + ++ C
Sbjct: 286 FRCRP--------------------------KLQCKSGFIQDALGNCIDIN----ECLSI 315
Query: 698 ACTCPVGVACDSVSGE--CGKRCPAGFQGEDCGQECPVGTFGVNC--SSSCSCGGAPCHG 753
+ CP+G C + G C K P +CG+ + G C C+ PC G
Sbjct: 316 SAPCPIGHTCINTEGSYTCQKNVP------NCGRGYHLNEEGTRCVDVDECAPPAEPC-G 368
Query: 754 VTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPG-FVGSR 812
+C PG +C G + G +C + C PG G +
Sbjct: 369 KGHRCVNSPG----SFRCECKTGYYFDGISRMC----------VDVNECQRYPGRLCGHK 414
Query: 813 CQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHP 872
C++ G Y SC + DG CS +P C + C + S+
Sbjct: 415 CENT--LGSYLCSCSVGFRLSVDGRSCEDINECSSSP------CSQECANVYG----SYQ 462
Query: 873 CNCSAGHGSCDAISGLCLCEAGYVGPRCE--QQCPQGHFGPGCEQRCQCQHGAACDHVSG 930
C C G+ D G CE +C G C RC G S
Sbjct: 463 CYCRRGYQLSDV-----------DGVTCEDIDECALPTGGHICSYRCINIPG------SF 505
Query: 931 ACTCP-AGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC-AE 988
C+CP +G+R P G +C+ C G ++N +C G G RC A
Sbjct: 506 QCSCPSSGYR------LAPN---GRNCQDIDECVTGIHNCSINETCFNIQG--GFRCLAF 554
Query: 989 TCP 991
CP
Sbjct: 555 ECP 557
Score = 48.1 bits (113), Expect = 6e-05
Identities = 102/422 (24%), Positives = 137/422 (32%), Gaps = 98/422 (23%)
Query: 1048 CQNGGTCDPVSGH------CACPEGWA----GLACE--KECLPRDVRAGCRHSGGCLN-- 1093
C+ GG C C+C G+ G++CE EC+ CR C+N
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS--HSCRLGESCINTV 237
Query: 1094 GGLCDPHTGRCLCPAGWTGDK-CQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPG 1152
G C T D C+ E + +C P C + G+ RC P
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKD------IDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 1153 FTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC--------------SCAAGYH 1198
C+ + G +C + +C + C P TC +C GYH
Sbjct: 292 LQ---CKSGFIQDALG-NCIDINECLSISAPC-PIGHTCINTEGSYTCQKNVPNCGRGYH 346
Query: 1199 GPSCQQRC-PPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCP----- 1250
RC P E C G C + G+ C C TG+ + C
Sbjct: 347 LNEEGTRCVDVDECAPPAEP---CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNEC 403
Query: 1251 QGRFGPNCTHVCGCGQGA-ACDPVTGTCLCPPGRAGVRCE-------RGCPQNRFGVGCE 1302
Q G C H C G+ C G L GR+ CE C Q V
Sbjct: 404 QRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRS---CEDINECSSSPCSQECANVYGS 460
Query: 1303 HTCSCRNG-GLCHASNGSC----SCGLGWTGRHCELAC--PPGRYGAACHLECSCHNNST 1355
+ C CR G L +C C L G C C PG + +CSC
Sbjct: 461 YQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSF------QCSC----- 509
Query: 1356 CEPATGTCRCGPGFYGQACE--HPCPPGFHGAGCQGLCWCQHGAPCDPISGRCL---CPA 1410
P++G R P G+ C+ C G H C+ G RCL CP
Sbjct: 510 --PSSG-YRLAPN--GRNCQDIDECVTGIHNCSINETCFNIQG------GFRCLAFECPE 558
Query: 1411 GF 1412
+
Sbjct: 559 NY 560
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.142 0.535
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,462,498
Number of Sequences: 37866
Number of extensions: 5758061
Number of successful extensions: 54987
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 260
Number of HSP's successfully gapped in prelim test: 418
Number of HSP's that attempted gapping in prelim test: 15377
Number of HSP's gapped (non-prelim): 11779
length of query: 1541
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1426
effective length of database: 13,892,928
effective search space: 19811315328
effective search space used: 19811315328
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.