Guide to the Human Genome
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Name: FBN1 Sequence: fasta or formatted (2871aa) NCBI GI: 24430141
Description:

fibrillin 1 precursor

Referenced in:

Extracellular Matrix

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.3         96           2
 C cysteine           12.6        362           3
 D aspartate           6.0        173           2
 E glutamate           7.0        201           2
 F phenylalanine       2.9         84           2
 G glycine            10.7        307           4
 H histidine           1.7         48           2
 I isoleucine          5.2        149           2
 K lysine              3.9        111           3
 L leucine             4.9        141           2
 M methionine          1.8         52           3
 N asparagine          6.5        188           2
 P proline             6.1        175           4
 Q glutamine           3.5        100           1
 R arginine            4.6        131           2
 S serine              6.0        173           3
 T threonine           5.8        166           2
 V valine              3.8        108           1
 W tryptophan          0.5         13           1
 Y tyrosine            3.2         93           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   fibrillin 1 precursor 
FBN2                  0.714   fibrillin 2 precursor 
FBN3                  0.619   fibrillin 3 precursor 
LTBP4                 0.082   latent transforming growth factor beta binding prot...
LTBP4                 0.082   latent transforming growth factor beta binding prot...
LTBP4                 0.082   latent transforming growth factor beta binding prot...
NOTCH2                0.077   notch 2 preproprotein 
LTBP2                 0.076   latent transforming growth factor beta binding protei...
LTBP1                 0.075   latent transforming growth factor beta binding prote...
LTBP1                 0.075   latent transforming growth factor beta binding prote...
NOTCH1                0.071   notch1 preproprotein 
NOTCH3                0.065   Notch homolog 3 
LTBP3                 0.063   latent transforming growth factor beta binding prote...
LTBP3                 0.062   latent transforming growth factor beta binding prot...
NOTCH4                0.048   notch4 preproprotein 
MEGF6                 0.042   EGF-like-domain, multiple 3 
FBLN2                 0.042   fibulin 2 isoform b precursor 
FBLN2                 0.039   fibulin 2 isoform a precursor 
EYS                   0.035   eyes shut homolog isoform 1 
FBLN1                 0.034   fibulin 1 isoform D 
MATN2                 0.034   matrilin 2 isoform b precursor 
MATN2                 0.034   matrilin 2 isoform a precursor 
FBLN1                 0.034   fibulin 1 isoform B precursor 
FBLN1                 0.034   fibulin 1 isoform A precursor 
FBLN1                 0.034   fibulin 1 isoform C precursor 
HMCN1                 0.034   hemicentin 1 
SCUBE2                0.031   CEGP1 protein 
SCUBE3                0.031   signal peptide, CUB domain, EGF-like 3 
SCUBE1                0.030   signal peptide, CUB domain, EGF-like 1 
JAG1                  0.030   jagged 1 precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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