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Search of human proteins with 148833508
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148833508 notch1 preproprotein [Homo sapiens]
(2555 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148833508 notch1 preproprotein [Homo sapiens] 5608 0.0
gi|24041035 notch 2 preproprotein [Homo sapiens] 2885 0.0
gi|134244285 Notch homolog 3 [Homo sapiens] 2038 0.0
gi|55770876 notch4 preproprotein [Homo sapiens] 1271 0.0
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 630 e-180
gi|4557679 jagged 1 precursor [Homo sapiens] 518 e-146
gi|24430141 fibrillin 1 precursor [Homo sapiens] 511 e-144
gi|66346695 fibrillin 2 precursor [Homo sapiens] 511 e-144
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 501 e-141
gi|56237021 fibrillin 3 precursor [Homo sapiens] 494 e-139
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 481 e-135
gi|122937283 6720455I24Rik homolog [Homo sapiens] 464 e-130
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 436 e-121
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 370 e-101
gi|112420992 crumbs homolog 2 [Homo sapiens] 348 3e-95
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 285 5e-76
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 282 3e-75
gi|110735443 delta-like 1 [Homo sapiens] 281 8e-75
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 272 3e-72
gi|148886654 polydom [Homo sapiens] 272 4e-72
gi|4557733 latent transforming growth factor beta binding protei... 270 1e-71
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 270 1e-71
gi|110347437 latent transforming growth factor beta binding prot... 270 2e-71
gi|110347412 latent transforming growth factor beta binding prot... 269 3e-71
gi|110347431 latent transforming growth factor beta binding prot... 269 3e-71
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 261 8e-69
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 230 2e-59
gi|188528675 slit homolog 1 [Homo sapiens] 227 1e-58
gi|153946395 tenascin C precursor [Homo sapiens] 221 7e-57
gi|46249414 latent transforming growth factor beta binding prote... 221 9e-57
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 5608 bits (14548), Expect = 0.0
Identities = 2555/2555 (100%), Positives = 2555/2555 (100%)
Query: 1 MPPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDP 60
MPPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDP
Sbjct: 1 MPPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDP 60
Query: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLL 120
NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLL
Sbjct: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLL 120
Query: 121 TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN 180
TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN
Sbjct: 121 TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN 180
Query: 181 ECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVT 240
ECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVT
Sbjct: 181 ECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVT 240
Query: 241 HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ 300
HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ
Sbjct: 241 HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ 300
Query: 301 LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE 360
LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE
Sbjct: 301 LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE 360
Query: 361 CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA 420
CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA
Sbjct: 361 CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA 420
Query: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP 480
NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP 480
Query: 481 GYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNG 540
GYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNG
Sbjct: 481 GYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNG 540
Query: 541 AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC 600
AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC
Sbjct: 541 AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC 600
Query: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 660
ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID
Sbjct: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 660
Query: 661 GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC 720
GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC
Sbjct: 661 GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC 720
Query: 721 NSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR 780
NSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR
Sbjct: 721 NSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR 780
Query: 781 EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN 840
EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN
Sbjct: 781 EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN 840
Query: 841 GGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYS 900
GGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYS
Sbjct: 841 GGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYS 900
Query: 901 GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC 960
GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC
Sbjct: 901 GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC 960
Query: 961 TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH 1020
TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH
Sbjct: 961 TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH 1020
Query: 1021 DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ 1080
DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ
Sbjct: 1021 DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ 1080
Query: 1081 YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS 1140
YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS
Sbjct: 1081 YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS 1140
Query: 1141 YCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLD 1200
YCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLD
Sbjct: 1141 YCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLD 1200
Query: 1201 LPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260
LPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV
Sbjct: 1201 LPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260
Query: 1261 GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGG 1320
GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGG
Sbjct: 1261 GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGG 1320
Query: 1321 TCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTG 1380
TCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTG
Sbjct: 1321 TCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTG 1380
Query: 1381 PECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDI 1440
PECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDI
Sbjct: 1381 PECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDI 1440
Query: 1441 PPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYF 1500
PPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYF
Sbjct: 1441 PPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYF 1500
Query: 1501 SDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLD 1560
SDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLD
Sbjct: 1501 SDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLD 1560
Query: 1561 CAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYY 1620
CAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYY
Sbjct: 1561 CAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYY 1620
Query: 1621 GREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVYLEI 1680
GREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVYLEI
Sbjct: 1621 GREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVYLEI 1680
Query: 1681 DNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAQLHFMYVA 1740
DNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAQLHFMYVA
Sbjct: 1681 DNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAQLHFMYVA 1740
Query: 1741 AAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNA 1800
AAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNA
Sbjct: 1741 AAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNA 1800
Query: 1801 SDGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMSAMAP 1860
SDGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMSAMAP
Sbjct: 1801 SDGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMSAMAP 1860
Query: 1861 TPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL 1920
TPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL
Sbjct: 1861 TPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL 1920
Query: 1921 HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQIL 1980
HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQIL
Sbjct: 1921 HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQIL 1980
Query: 1981 IRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNN 2040
IRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNN
Sbjct: 1981 IRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNN 2040
Query: 2041 VDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDI 2100
VDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDI
Sbjct: 2041 VDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDI 2100
Query: 2101 AQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRK 2160
AQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRK
Sbjct: 2101 AQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRK 2160
Query: 2161 PSSKGLACGSKEAKDLKARRKKSQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLP 2220
PSSKGLACGSKEAKDLKARRKKSQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLP
Sbjct: 2161 PSSKGLACGSKEAKDLKARRKKSQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLP 2220
Query: 2221 SPFQQSPSVPLNHLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVAS 2280
SPFQQSPSVPLNHLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVAS
Sbjct: 2221 SPFQQSPSVPLNHLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVAS 2280
Query: 2281 GTSTVLGSSSGGALNFTVGGSTSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAP 2340
GTSTVLGSSSGGALNFTVGGSTSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAP
Sbjct: 2281 GTSTVLGSSSGGALNFTVGGSTSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAP 2340
Query: 2341 SLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPA 2400
SLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPA
Sbjct: 2341 SLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPA 2400
Query: 2401 NIQQQQSLQPPPPPPQPHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQE 2460
NIQQQQSLQPPPPPPQPHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQE
Sbjct: 2401 NIQQQQSLQPPPPPPQPHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQE 2460
Query: 2461 SPALPTSLPSSLVPPVTAAQFLTPPSQHSYSSPVDNTPSHQLQVPEHPFLTPSPESPDQW 2520
SPALPTSLPSSLVPPVTAAQFLTPPSQHSYSSPVDNTPSHQLQVPEHPFLTPSPESPDQW
Sbjct: 2461 SPALPTSLPSSLVPPVTAAQFLTPPSQHSYSSPVDNTPSHQLQVPEHPFLTPSPESPDQW 2520
Query: 2521 SSSSPHSNVSDWSEGVSSPPTSMQSQIARIPEAFK 2555
SSSSPHSNVSDWSEGVSSPPTSMQSQIARIPEAFK
Sbjct: 2521 SSSSPHSNVSDWSEGVSSPPTSMQSQIARIPEAFK 2555
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 2885 bits (7479), Expect = 0.0
Identities = 1381/2563 (53%), Positives = 1713/2563 (66%), Gaps = 150/2563 (5%)
Query: 2 PPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAA-NGTEACVCGGAFVGPRCQDP 60
P LL LL L L A A +C E C+N G C NGT C C F+G CQ
Sbjct: 6 PALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR 65
Query: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNAC-LTNPCRNGGTCDL 119
+PC C+N GTC G A C CA GF+G C + C ++ PC NGGTC +
Sbjct: 66 DPCEKNRCQNGGTCVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHM 123
Query: 120 LTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDV 179
L+ Y+C C G++GK CQ D C S+PCANG C + C C F G C DV
Sbjct: 124 LSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDV 183
Query: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV 239
NEC PG C+HGGTC N GSY+C C TG C+ YVPC+PSPC NGGTCR TGD
Sbjct: 184 NEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDF 242
Query: 240 THECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDEC 299
T EC CLPGF G CE NIDDCP + C+NGG CVDGVNTYNCRCPP+WTGQ+CTEDVDEC
Sbjct: 243 TFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC 302
Query: 300 QLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC 359
L PNACQNGGTC N +GGY CVCVNGW+G+DCSENIDDCA A+C G+TC DRVASF C
Sbjct: 303 LLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSC 362
Query: 360 ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG 419
CP G+ GLLCHL+DACISNPC++G+ CDTNP+NG+ ICTCP GY G C++DVDEC++
Sbjct: 363 MCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA 422
Query: 420 -ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCIC 478
+NPCEHAGKC+NT G+F C+CL+GY GPRCE+D+NEC S+PCQNDATCLD+IG F C+C
Sbjct: 423 NSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLC 482
Query: 479 MPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCK 538
MPG++GVHCE+ +EC S+PC++NG+C+DK+N FQC CP GFTG +CQ D+D+C+STPC
Sbjct: 483 MPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCL 542
Query: 539 NGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGH 598
NGAKC+D PN Y C C G+TG CE +ID CDPDPCH+G C+DG+ ++TC+C PGY G
Sbjct: 543 NGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGA 602
Query: 599 HCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDK 658
C I+EC S PC + G C D N Y C C GT+G NCEIN DDCAS+PC G C+D
Sbjct: 603 ICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDG 662
Query: 659 IDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVN 718
I+ Y C C PG+TG CNI+IDECA NPC G TC +G+NGF C CPEG H P+C S+VN
Sbjct: 663 INRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVN 722
Query: 719 ECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCT 778
EC SNPC+HG C L+GYKC CD GW G NC+++ NEC SNPC NGGTC ++ +GY CT
Sbjct: 723 ECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCT 782
Query: 779 CREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC 838
C++GF G NCQ NI+ECASNPCLNQGTC DD++GY C+C+LPYTG C+ VLAPC+P+PC
Sbjct: 783 CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPC 842
Query: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAG 898
N C++S ++ES++C+C GWQGQ C +DI+EC+ PC + C NT G Y C C G
Sbjct: 843 ENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPG 902
Query: 899 YSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGA 958
+SG +CE DIDDC NPC NGGSC DG+NT C CLPGF G C+ D+NEC S+PC+NG
Sbjct: 903 FSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGG 962
Query: 959 NCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
C+D V+SYTC C AGF G+HCENN +CTESSCFNGGTCVDGINSF+CLCP GFTGS+C
Sbjct: 963 TCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
Query: 1019 QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH 1078
H++NEC S PCL+ GTC DG G+YRC+CP GYTG NCQ LV+ C SPCKN G C Q
Sbjct: 1023 LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKK 1082
Query: 1079 TQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
+ +C CPSGW G YCDVP+VSC++AA R+GV V LCQH G+C++AGNTH+C+C GYT
Sbjct: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT 1142
Query: 1139 GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC 1198
GSYCE+ +DEC+ +PCQ+GATC+D++GGY C+CV GY GVNC E+DEC + PCQNGGTC
Sbjct: 1143 GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC 1202
Query: 1199 LDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPG 1258
+DL N +KCSCP GT+G+ CE N+DDC +R P C N G C+D++GGYSC C PG
Sbjct: 1203 IDLVNHFKCSCPPGTRGLLCEENIDDC-------ARGPHCLNGGQCMDRIGGYSCRCLPG 1255
Query: 1259 FVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 1318
F GERCEGD+NECLSNPC + G+ +C+Q ND+ C CR+ TGR CE+ ++ C PC N
Sbjct: 1256 FAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLN 1315
Query: 1319 GGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 1378
GGTCAVASN GFIC+CP GF GA C++ +CG ++C G C+ P C C P
Sbjct: 1316 GGTCAVASNMPDGFICRCPPGFSGARCQS---SCGQVKCRKGEQCVHTASGPRCFCPSP- 1371
Query: 1379 TGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGR 1438
+C+ +S +PC + G+C P + P+Y C C F+G C +
Sbjct: 1372 --RDCESGCAS-----SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELY---------- 1414
Query: 1439 DIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWK 1498
PP C C + A + VC CN+HAC WDGGDCSL +PW NC+ L CW
Sbjct: 1415 TAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWD 1474
Query: 1499 YFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDG 1558
Y ++ CD CN+ CLFD F+CQ C YD+YC DHF D HCDQGCNS EC WDG
Sbjct: 1475 YINN-QCDELCNTVECLFDNFECQGNSKTCK--YDKYCADHFKDNHCDQGCNSEECGWDG 1531
Query: 1559 LDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFP 1618
LDCA PE LA GTLV+VVLMPPEQL + FLR L +LHTN+ KRD+ G+ M++P
Sbjct: 1532 LDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLRIKRDSQGELMVYP 1591
Query: 1619 YYG-REEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVY 1677
YYG + ++K + R + LPG E +V GS V+
Sbjct: 1592 YYGEKSAAMKKQRMTRRS-----------------LPGEQE----------QEVAGSKVF 1624
Query: 1678 LEIDNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAQLHFM 1737
LEIDNRQCVQ S CF++ AA L + A G+L+ Y + +V SE++ P L+ +
Sbjct: 1625 LEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLS--YPLVSVVSESLTPERTQLLYLL 1682
Query: 1738 YVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKV-SEASKKKRREPLGEDSVGLKP 1796
A A ++LF + GV+++ KR+R+HG LW PEGF + +AS KRREP+G+D+VGLK
Sbjct: 1683 --AVAVVIILFIILLGVIMA-KRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKN 1739
Query: 1797 LK-NASDGALMDDNQNE-W-GDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADL 1853
L S+ L+ +E W DE + KK + E+ +L + DD D R WTQQHL+AAD+
Sbjct: 1740 LSVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADI 1799
Query: 1854 RMS-AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEE-EDAPA-VI 1910
R + ++A TPPQ E + D +DVNVRGPDG TPLM+AS GG + + +E+ ED+ A +I
Sbjct: 1800 RRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANII 1859
Query: 1911 SDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVS 1970
+D +YQGASL QTDRTGE ALHLAARYSR+DAAKRLL+A ADAN QDNMGR PLHAAV+
Sbjct: 1860 TDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVA 1919
Query: 1971 ADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKS 2030
ADAQGVFQILIRNR TDLDARM+DGTTPLILAARLAVEGM+ +LIN ADVNAVDD GKS
Sbjct: 1920 ADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKS 1979
Query: 2031 ALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDIT 2090
ALHWAAAVNNV+A ++LLKNGAN+DMQ+N+EETPLFLAAREGSYE AK+LLDHFANRDIT
Sbjct: 1980 ALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDIT 2039
Query: 2091 DHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLK 2150
DHMDRLPRD+A++RMHHDIVRLLDEYN+ SP G L T LSP +C PN SLK
Sbjct: 2040 DHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPP--GTVL--TSALSPVICGPNRSFLSLK 2095
Query: 2151 PGVQGKKVRKPSSK-----GLACGSKEAKDLK-ARRKKSQDGKGCLLDSSGMLSPVDSLE 2204
GKK R+PS+K L +KEAKD K +RRKKS K L +SS LSPVDSLE
Sbjct: 2096 HTPMGKKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLE 2155
Query: 2205 SPHGYLSDVASPPLLPSP--FQQSPSVPLNHLPGMPDTHLGIGH-LNVAAKPEMAALGGG 2261
SPH Y+SD S P++ SP Q SP+ L P + H L+ + EM L G
Sbjct: 2156 SPHTYVSDTTSSPMITSPGILQASPNPML--ATAAPPAPVHAQHALSFSNLHEMQPLAHG 2213
Query: 2262 GRLAFETGPPRLSHLPVASGTSTVLGSSSGGALNFTVGGSTSLNGQCEWLSRLQSGMVPN 2321
+ LSH + S GS S G+L+ + +W++R++ +
Sbjct: 2214 ASTVLPSVSQLLSHHHIVSP-----GSGSAGSLS----RLHPVPVPADWMNRME--VNET 2262
Query: 2322 QYNPLRGSV-APGPLSTQAPSLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQPHLV 2380
QYN + G V AP + + Q H + L ++++Q +P +A
Sbjct: 2263 QYNEMFGMVLAPAEGTHPGIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIA------ 2316
Query: 2381 QTQQVQPQNLQMQQQNLQPANIQQQQSLQPPPPPPQPHLGVSSAASGHLGRSFLSGEPSQ 2440
QPA Q QS PP A +G L + E ++
Sbjct: 2317 -----------------QPAGAPQPQSTCPP------------AVAGPLPTMYQIPEMAR 2347
Query: 2441 ADVQPLGPSSLAVHTILP-QESPALPTSLPSSLVPPVTAAQFLTPPSQHSY--SSPVDNT 2497
PS ++P Q+ T LP+ P + ++ TPPSQHSY S+ + T
Sbjct: 2348 L------PSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERT 2401
Query: 2498 PSHQLQVP-EHPFLTPSPESPDQWSSSSPHSNVSDWSEGVSSP 2539
PSH + EHP+LTPSPESPDQWSSSSPHS SDWS+ +SP
Sbjct: 2402 PSHSGHLQGEHPYLTPSPESPDQWSSSSPHS-ASDWSDVTTSP 2443
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 2038 bits (5281), Expect = 0.0
Identities = 1024/2210 (46%), Positives = 1330/2210 (60%), Gaps = 175/2210 (7%)
Query: 141 ADPCAS-NPCANGGQCLPFEA-SYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNE 198
A PC +PCANGG+C + C CPP + G C+ + + C P C G C +
Sbjct: 40 APPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGP--CAGRGVCQSS 96
Query: 199 V----GSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNC 254
V + C C GP+C P PC SPC +G C D C+C PG+ G++C
Sbjct: 97 VVAGTARFSCRCPRGFRGPDCSLPD-PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSC 155
Query: 255 EENIDDCP-GNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCH 313
++D+C G C++GG C++ ++ C+CP +TG C C P+ C+NGGTC
Sbjct: 156 RSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCA--PSPCRNGGTCR 213
Query: 314 NTHG-GYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHL 372
+ Y+C C+ G+ G++C N+DDC C +G TC D V ++ C+CP TG C
Sbjct: 214 QSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTE 273
Query: 373 N-DACISNP--CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC 429
+ D C P C+ G C N + G + C C +G+TG +CSQ++D+C+ C H C
Sbjct: 274 DVDECQLQPNACHNGGTC-FNTLGGHS-CVCVNGWTGESCSQNIDDCATAV--CFHGATC 329
Query: 430 INTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQI--GEFQCICMPGYEGVHC 487
+ + SF C C G TG C +D + CVSNPC DA C G C C PG+ G C
Sbjct: 330 HDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGAC 388
Query: 488 EVNTDECA--SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLD 545
+ + DEC+ ++PC H GRC++ F C+C G+TG C+ DV+EC S PC+N A CLD
Sbjct: 389 DQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLD 448
Query: 546 GPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNI 604
+TC+C G+TGT+CEVDIDEC PC + G CKD V F+C C G++G C+ ++
Sbjct: 449 RIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDV 508
Query: 605 NECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYEC 664
+EC+S PCR+G C D+ + Y C C +G G C+ N+DDC+ PC G C+D I + C
Sbjct: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSC 568
Query: 665 ACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNP 724
AC PGYTG+ C +DEC PC +GG C D ++ + CRCP G C +++C SNP
Sbjct: 569 ACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNP 628
Query: 725 CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKD-------------- 770
C G CRD +N Y C C PG++G C++ NEC S+PC GG+C D
Sbjct: 629 CTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSL 688
Query: 771 -----------------------MTSGYVCTCREGFSGPNCQTNI--NECASNPCLNQGT 805
G+ C C G+SGP C ++ + C S PC GT
Sbjct: 689 PPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGT 748
Query: 806 CIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQT 865
C D G+ C C G CE+ L+PC P+PC +GG C +S + C CP GWQG
Sbjct: 749 CSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRC-ESAPGQLPVCSCPQGWQGPR 806
Query: 866 CEVDINECV-LSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTD 924
C+ D++EC +PC C N G + C C GY+G +C+ DI+DC PNPC NGGSC D
Sbjct: 807 CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQD 866
Query: 925 GINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNT 984
G+ + C CLPGF G C D++EC S+PC G CTD V S+TCTCP G+ G HCE +
Sbjct: 867 GVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT-CTDHVASFTCTCPPGYGGFHCEQDL 925
Query: 985 PDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYR 1044
PDC+ SSCFNGGTCVDG+NSF+CLC PG+TG++CQH+ + C S+PCLHGG C +R
Sbjct: 926 PDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFR 985
Query: 1045 CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 1104
CTC + +TGP CQ LV WC PC+NGG+C QT C CP GW+G CD+ S+ C A
Sbjct: 986 CTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY--CLCPPGWSGRLCDIRSLPCREA 1043
Query: 1105 AQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYL 1164
A + GV + +LCQ GG CVD ++H+C C G TGS+CE VD C PCQ+G TC Y+
Sbjct: 1044 AAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYM 1103
Query: 1165 GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1224
GGY C+C+ GY+G NC +++DEC S PCQ+GG+C+DL Y CSCP GT GV CEIN DD
Sbjct: 1104 GGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDD 1163
Query: 1225 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNC 1284
C P P+ P+C +NGTCVD VGG+ CTCPPG+ G RCE D+NEC S C A T++C
Sbjct: 1164 CGPG-PPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDC 1222
Query: 1285 VQRVND-FHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARG--FICKCPAGFE 1341
+Q F C C AG +G RC++V++ C+ +PC++GG C + G F C C F
Sbjct: 1223 LQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1282
Query: 1342 GATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQ-FPASSP-----CLGGN 1395
G CE AR+C L+C G C PR P C C +GP C+ FP S P
Sbjct: 1283 GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAA 1342
Query: 1396 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQ 1455
PC + G+C P +PF+RC C + G C A P E C CQ
Sbjct: 1343 PCLHGGSCRPAPLAPFFRCACAQGWTGPRCE---------APAAAPEVSEEPRCPRAACQ 1393
Query: 1456 EDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCL 1515
G++ C +CN+ CGWDGGDCSL+ DPW+ C ++LQCW+ F++ CD C+S CL
Sbjct: 1394 AKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC-EALQCWRLFNNSRCDPACSSPACL 1452
Query: 1516 FDGFDCQRA--EGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGT 1573
+D FDC E CNP+Y++YC DHF+DG CDQGCN+ EC WDGLDCA VP LA G
Sbjct: 1453 YDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVPALLARGV 1512
Query: 1574 LVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYYGREEELRKHPIKR 1633
LV+ VL+PPE+L SS FL+ LS +L T++ F+ DAHGQ M+FPY+ R P
Sbjct: 1513 LVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYH------RPSP--- 1563
Query: 1634 AAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVYLEIDNRQCVQA--SSQ 1691
GSE R RREL P +V GS+V LEIDNR C+Q+ +
Sbjct: 1564 ----------------------GSE-PRARRELAP-EVIGSVVMLEIDNRLCLQSPENDH 1599
Query: 1692 CFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAQLHFMYVAAAAFVLLFFVG 1751
CF A A +LGAL+++ L+ PY + V+ E +EPP P+ + A A +LL +
Sbjct: 1600 CFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEPPEPSVPLLPLLVAGAVLLLVILV 1659
Query: 1752 CGVLLSRKRRRQHGQLWFPEGFKVSE---ASKKKRREPLGEDSVGLKPLKNASDGALMDD 1808
GV+++R R+R+H LWFPEGF + + + K RREP+G+D++G+K + A +LM +
Sbjct: 1660 LGVMVAR-RKREHSTLWFPEGFSLHKDVASGHKGRREPVGQDALGMKNM--AKGESLMGE 1716
Query: 1809 NQNEWGDEDL-ETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMS-AMAPTPPQGE 1866
+W D + E K+ + EEP + ++ D RQWTQ HL AAD+R++ AMA TPPQG+
Sbjct: 1717 VATDWMDTECPEAKRLKVEEPGM--GAEEAVDCRQWTQHHLVAADIRVAPAMALTPPQGD 1774
Query: 1867 VDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEE---DAPAVISDFIYQGASLHNQ 1923
DAD MDVNVRGPDGFTPLM+AS GG LE +EE+E + ++ISD I QGA L +
Sbjct: 1775 ADADGMDVNVRGPDGFTPLMLASFCGGALEPMPTEEDEADDTSASIISDLICQGAQLGAR 1834
Query: 1924 TDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRN 1983
TDRTGETALHLAARY+R+DAAKRLL+A AD N QD+ GRTPLH AV+ADAQGVFQILIRN
Sbjct: 1835 TDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRN 1894
Query: 1984 RATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDA 2043
R+TDLDARM DG+T LILAARLAVEGM+E+LI SHADVNAVD+LGKSALHWAAAVNNV+A
Sbjct: 1895 RSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEA 1954
Query: 2044 AVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQE 2103
+ LLKNGANKDMQ+++EETPLFLAAREGSYE AK+LLDHFANR+ITDH+DRLPRD+AQE
Sbjct: 1955 TLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQE 2014
Query: 2104 RMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQG-KKVRKPS 2162
R+H DIVRLLD+ + RSP G L P LC P +L LK G KK R+P
Sbjct: 2015 RLHQDIVRLLDQPSGPRSPP-------GPHGLGPLLCPPGAFLPGLKAAQSGSKKSRRPP 2067
Query: 2163 SK-GLACGSKEAKDLKARRKKSQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLPS 2221
K GL + +K + G L DSS LSPVDSL+SP + PP P
Sbjct: 2068 GKAGLGPQGPRGRG----KKLTLACPGPLADSSVTLSPVDSLDSPRPF----GGPPASPG 2119
Query: 2222 PFQQSPSVPLNHLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPP 2271
F PL G A +A LGG GR PP
Sbjct: 2120 GF------PLE----------GPYAAATATAVSLAQLGGPGRAGLGRQPP 2153
Score = 1427 bits (3693), Expect = 0.0
Identities = 684/1536 (44%), Positives = 862/1536 (56%), Gaps = 178/1536 (11%)
Query: 54 GPRCQDPNPCLS-TPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCR 112
GP P PCL +PC N G C + R + AC C G+ G C L++ C + PC
Sbjct: 35 GPGAAAP-PCLDGSPCANGGRCTQLPSR---EAACLCPPGWVGERC--QLEDPCHSGPCA 88
Query: 113 NGGTCDLLTLT---EYKCRCPPGWSGKSCQQADPCASNPCANGGQC-LPFEASYICHCPP 168
G C + + CRCP G+ G C DPC S+PCA+G +C + + ++C CPP
Sbjct: 89 GRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPP 148
Query: 169 SFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQ 228
+ G +CR DV+EC + CRHGGTC N GS+RC C A +TGP CE P VPC+PSPC+
Sbjct: 149 GYQGRSCRSDVDEC-RVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCR 207
Query: 229 NGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWT 288
NGGTCR +GD+T++CACLPGF GQNCE N+DDCPG+ C NGG CVDGVNTYNC+CPPEWT
Sbjct: 208 NGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWT 267
Query: 289 GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA 348
GQ+CTEDVDECQL PNAC NGGTC NT GG++CVCVNGWTGE CS+NIDDCA+A CFHGA
Sbjct: 268 GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGA 327
Query: 349 TCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPA 408
TCHDRVASFYC CP G+TGLLCHL+DAC+SNPC+E + CDTNPVNG+AICTCP G+TG A
Sbjct: 328 TCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGA 387
Query: 409 CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL 468
C QDVDECS+GANPCEH G+C+NT GSF CQC +GYTGPRCE DVNEC+S PC+N ATCL
Sbjct: 388 CDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCL 447
Query: 469 DQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYD 528
D+IG+F CICM G+ G +CEV+ DEC SSPC++ G C D++N F C CP+GF+G CQ D
Sbjct: 448 DRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLD 507
Query: 529 VDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFT 588
VDECASTPC+NGAKC+D P+ Y C C EG+ GT C+ ++D+C PDPCH+G C DG+A+F+
Sbjct: 508 VDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFS 567
Query: 589 CLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASS 648
C C PGYTG CE+ ++EC SQPCRHGG C D + YLC C GTTG NCE+N+DDCAS+
Sbjct: 568 CACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN 627
Query: 649 PCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGY 708
PC G C D I+ Y+C C+PG+TG +CN+ I+ECA +PC GG+C DG NGF C CP G
Sbjct: 628 PCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGS 687
Query: 709 HDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNC--DINNNECESNPCVNGG 766
P CL + C PC HG C D+ G++C C+PGWSG C + + CES PC GG
Sbjct: 688 LPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG 747
Query: 767 TCKDMTSGY--------------------------------------VCTCREGFSGPNC 788
TC G+ VC+C +G+ GP C
Sbjct: 748 TCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRC 807
Query: 789 QTNINECAS-NPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
Q +++ECA PC G C + + C C YTG +C+ + C P+PC NGG C+
Sbjct: 808 QQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ-- 865
Query: 848 EDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
+ SFSC C G+ G C D++EC+ +PC G +C + + C C GY G +CE D
Sbjct: 866 DGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHCEQD 924
Query: 908 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCT------ 961
+ DC P+ C NGG+C DG+N+ C C PG+ G C+ + + C S PC +G C+
Sbjct: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
Query: 962 --DCVDSYT----------------------------CTCPAGFSGIHCENNTPDCTESS 991
C++S+T C CP G+SG C+ + C E++
Sbjct: 985 RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAA 1044
Query: 992 ----------CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCG 1041
C GG CVD +S C+CP G TGS+C+ +V+ C +QPC HGGTC+ G
Sbjct: 1045 AQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMG 1104
Query: 1042 SYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC 1101
Y C C GY G NC++ V C S PC++GG C +Y C CP G G+ C++ C
Sbjct: 1105 GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1164
Query: 1102 EVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGAT-- 1159
+D C H G CVD C C GYTG CE ++EC C T
Sbjct: 1165 ---GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRD 1221
Query: 1160 -CTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPN-----TYKCSCPRGT 1213
D GG+ C C AG+ G C + C S PCQ+GG C P T+ C C +
Sbjct: 1222 CLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPF 1281
Query: 1214 QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-------G 1266
G CE C R +C C G C CPPG G C G
Sbjct: 1282 WGPRCERVARSC--------RELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPG 1333
Query: 1267 DVN-ECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVA 1325
N C + PC G+ F C C G TG RCE+
Sbjct: 1334 ASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEA------------PAAAPEV 1381
Query: 1326 SNTARGFICKCPAGFEGATCENDARTCGSLRC-LNGGTCISGPRSPTCLCLGPFTGPECQ 1384
S R C A C+ R C S C +GG C P C
Sbjct: 1382 SEEPRCPRAACQAKRGDQRCD---RECNSPGCGWDGGDCSLSVGDPWRQC---------- 1428
Query: 1385 FPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPL 1444
L +N C+P SP CL ++ CH GG R P
Sbjct: 1429 -----EALQCWRLFNNSRCDPACSSP--ACL----YDNFDCH------AGGRERTCNPVY 1471
Query: 1445 IEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCS 1480
+ C + + C CN CGWDG DC+
Sbjct: 1472 EK------YCADHFADGRCDQGCNTEECGWDGLDCA 1501
Score = 989 bits (2558), Expect = 0.0
Identities = 521/1496 (34%), Positives = 706/1496 (47%), Gaps = 174/1496 (11%)
Query: 2 PPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEA-CVCGGAFVGPRCQDP 60
PP + L L LL A P C G C NGG+C EA C+C +VG RCQ
Sbjct: 21 PPPVRALPLLLLLAGPGAAAPPCLD-GSPCANGGRCTQLPSREAACLCPPGWVGERCQLE 79
Query: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLL 120
+PC S PC G C G A ++C C GF GP C P + CL++PC +G C +
Sbjct: 80 DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP--DPCLSSPCAHGARCSVG 137
Query: 121 TLTEYKCRCPPGWSGKSCQ-QADPC-ASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD 178
+ C CPPG+ G+SC+ D C PC +GG CL S+ C CP + GP C
Sbjct: 138 PDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 197
Query: 179 VNECGQKPGLCRHGGTCHNEVG-SYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTG 237
C P CR+GGTC +Y C C G NCE C C NGGTC G
Sbjct: 198 AVPCAPSP--CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTC-VDG 254
Query: 238 DVTHECACLPGFTGQNCEENIDDC--PGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTED 295
T+ C C P +TGQ C E++D+C N C NGG C + + ++C C WTG+ C+++
Sbjct: 255 VNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQN 314
Query: 296 VDECQLMPNACQNGGTCHN---------------------------------------TH 316
+D+C C +G TCH+ +
Sbjct: 315 IDDCATA--VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVN 372
Query: 317 GGYNCVCVNGWTGEDCSENIDDCASAA--CFHGATCHDRVASFYCECPHGRTGLLCHLN- 373
G C C G+TG C +++D+C+ A C H C + SF C+C G TG C +
Sbjct: 373 GRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDV 432
Query: 374 DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTL 433
+ C+S PC + C G+ C C +G+TG C D+DEC ++PC + G C + +
Sbjct: 433 NECLSGPCRNQATCLDR--IGQFTCICMAGFTGTYCEVDIDECQ--SSPCVNGGVCKDRV 488
Query: 434 GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDE 493
F C C G++G C++DV+EC S PC+N A C+DQ ++C C G+EG C+ N D+
Sbjct: 489 NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDD 548
Query: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCV 553
C+ PC H+GRC+D I F C C G+TG C+ VDEC S PC++G KCLD + Y C
Sbjct: 549 CSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCR 607
Query: 554 CTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCR 613
C G TG +CEV+ID+C +PC +G C+DG+ + C+C+PG+TG C INEC+S PC
Sbjct: 608 CPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCG 667
Query: 614 HGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGS 673
GG+C D +N + C C G+ P C CA PC G C D G+ C CEPG++G
Sbjct: 668 EGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGP 727
Query: 674 MCNINI--DECAGNPCHNGGTCEDGINGF------------------------------- 700
C+ ++ D C PC GGTC GF
Sbjct: 728 RCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCE 787
Query: 701 -------TCRCPEGYHDPTCLSEVNEC-NSNPC-VHGACRDSLNGYKCDCDPGWSGTNCD 751
C CP+G+ P C +V+EC PC HG C + + C C G++G +CD
Sbjct: 788 SAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCD 847
Query: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVA 811
+ N+C+ NPC+NGG+C+D + C+C GF+GP C +++EC SNPC GTC D VA
Sbjct: 848 QDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVA 906
Query: 812 GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 871
+ C C Y G CE L C+PS C NGG C + SFSC+C G+ G C+ + +
Sbjct: 907 SFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC--VDGVNSFSCLCRPGYTGAHCQHEAD 964
Query: 872 ECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFC 931
C+ PC HG C H G+RC C ++G C+T +D C PC NGG C A+C
Sbjct: 965 PCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ--TGAYC 1022
Query: 932 DCLPGFRGTFCE----------EDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCE 981
C PG+ G C+ I C+ G C D S+ C CP G +G HCE
Sbjct: 1023 LCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE 1082
Query: 982 NNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCG 1041
C C +GGTC + + C C PG+ G C+ DV+EC SQPC HGG+C D
Sbjct: 1083 QEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVA 1142
Query: 1042 SYRCTCPQGYTGPNCQNLVHWC------DSSP-CKNGGKCWQTHTQYRCECPSGWTGLYC 1094
Y C+CP G G C+ C DS P C + G C +RC CP G+TGL C
Sbjct: 1143 RYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRC 1202
Query: 1095 DVPSVSCEVAAQRQGVDVARLCQHGGLCV-DAGNTHHCRCQAGYTGSYCEDLVDECSPSP 1153
+ C A H C+ D G C C AG++G C+ ++ C P
Sbjct: 1203 EADINECRSGACH--------AAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP 1254
Query: 1154 CQNGATCTDYLG-----GYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS 1208
CQ+G C G ++C C + G C C C G C P +C+
Sbjct: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCA 1314
Query: 1209 CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC--VDQVGGYSCTCPPGFVGERCEG 1266
CP G G C + + C + G+C + C C G+ G RCE
Sbjct: 1315 CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEA 1374
Query: 1267 -----DVNE---CLSNPCDA-RGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
+V+E C C A RG Q C + N C G G C S+ G + C+
Sbjct: 1375 PAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGC----GWDGGDC-SLSVGDPWRQCE 1429
Query: 1318 NGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCL-NGGTCISGPRSPTC 1372
+C F + C+ C S CL + C +G R TC
Sbjct: 1430 ---------------ALQCWRLFNNSRCD---PACSSPACLYDNFDCHAGGRERTC 1467
Score = 83.6 bits (205), Expect = 2e-15
Identities = 161/616 (26%), Positives = 232/616 (37%), Gaps = 120/616 (19%)
Query: 1951 SADANIQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARL--AVE 2008
+AD + M TP ADA G+ D++ R DG TPL+LA+ A+E
Sbjct: 1757 AADIRVAPAMALTPPQG--DADADGM----------DVNVRGPDGFTPLMLASFCGGALE 1804
Query: 2009 GM--------------LEDLINSHADVNA-VDDLGKSALHWAAAVNNVDAAVVLLKNGAN 2053
M + DLI A + A D G++ALH AA DAA LL GA+
Sbjct: 1805 PMPTEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGAD 1864
Query: 2054 KDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDR------LPRDIAQERMHH 2107
+ Q++ TPL A + ++L+ + + D+ M L +A E M
Sbjct: 1865 TNAQDHSGRTPLHTAVTADAQGVFQILIRN-RSTDLDARMADGSTALILAARLAVEGMVE 1923
Query: 2108 DIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRKPSSKGLA 2167
+++ + N V +L + L ++ + L LK G ++K +
Sbjct: 1924 ELIASHADVNAV--DELGKSALHWAAAVN----NVEATLALLKNG---------ANKDMQ 1968
Query: 2168 CGSKEAKDLKARRKKSQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLPSPFQQSP 2227
+E A R+ S + LLD D L+ DVA L
Sbjct: 1969 DSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDR---LPRDVAQERL------HQD 2019
Query: 2228 SVPLNHLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVASGTSTVLG 2287
V L P P + G L P A L G A ++G + P +G
Sbjct: 2020 IVRLLDQPSGPRSPPGPHGLGPLLCPPGAFLPG--LKAAQSGSKKSRRPPGKAGLGPQGP 2077
Query: 2288 SSSGGALNFTVGGSTSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAPSLQHGMV 2347
G L G L LS + S P + S PG + P
Sbjct: 2078 RGRGKKLTLACPGP--LADSSVTLSPVDSLDSPRPFGGPPAS--PGGFPLEGP------- 2126
Query: 2348 GPLHSSLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPANIQQQQS 2407
+++ A+A+S + G L QP P + L P + +
Sbjct: 2127 ---YAAATATAVS-LAQLGGPGRAGLGRQP---------PGGCVLSLGLLNPVAVPLDWA 2173
Query: 2408 LQPPPPPPQPHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQESPALPTS 2467
PPP PP P SFL P Q L P + + PQE P
Sbjct: 2174 RLPPPAPPGP--------------SFLL--PLAPGPQLLNPGT----PVSPQERP----- 2208
Query: 2468 LPSSLVPPVTAAQFLTPPSQHSYSSPVDNTPSHQLQVP-EHPFLTPSPESPDQWSSSSPH 2526
P L P ++ P+ ++SSP + L+VP EHP+LTPSPESP+ W+S SP
Sbjct: 2209 -PPYLAVPGHGEEY---PAAGAHSSP---PKARFLRVPSEHPYLTPSPESPEHWASPSPP 2261
Query: 2527 SNVSDWSEGVSSPPTS 2542
S +SDWSE SP T+
Sbjct: 2262 S-LSDWSESTPSPATA 2276
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 1271 bits (3288), Expect = 0.0
Identities = 705/1899 (37%), Positives = 965/1899 (50%), Gaps = 189/1899 (9%)
Query: 299 CQLMPNACQNGGTCHNTHGGYN-CVCVNGWTGEDCSENIDDCASAA-CFHGATCHDRVAS 356
C P C NGGTC + G C C G+ GE C + D C +A C +G +C +
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC-QFPDPCQNAQLCQNGGSCQALL-- 84
Query: 357 FYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDEC 416
P G +P+ +CTC G+TG C +++
Sbjct: 85 -----------------------PAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLED- 120
Query: 417 SLGANPCEHAGKC-INTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQ 475
+ C G+C I G +C C+ G+TG +C++ + C +NPC N CL + Q
Sbjct: 121 PCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQ 179
Query: 476 CICMPGYEGVHCEVNTDECASSP--CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECA 533
C C PG+EG CE + +EC P C C + + FQC CP G G C+ C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCP 239
Query: 534 STPCKNGAKCLDGPNT----YTCVCTEGYTGTHCEVDIDECDPDPCHYG-SCKDGVATFT 588
C NG C P + C+C G+ G CEV+ D C C G +C+DG+ T+T
Sbjct: 240 PRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYT 299
Query: 589 CLCRPGYTGHHCETNINECSSQP---CRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDC 645
CLC +TG C +++EC +Q CR+GGTCQ+ ++ C C+ G G +CE NLDDC
Sbjct: 300 CLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDC 359
Query: 646 ASSPCDSG-TCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDG-INGFT-C 702
++ C G TC+D++ + C C PG TG +C++ D C PCH C + G T C
Sbjct: 360 IAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLC 418
Query: 703 RCPEGYHDPTCLSEVNEC-----NSNPCVHG-ACRDSLNGYKCDCDPGWSGTNCDINNNE 756
C GY PTC +++EC +PC HG +C ++ + C C PG++G+ C+ ++NE
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNE 478
Query: 757 CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
C S PC G TC D+ + + C C G G C+ NECAS PCLN C D + G++C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Query: 817 CLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLS 876
CL ++G CE + C SPC NGG+C+ +F C C G++G C+ +++EC+
Sbjct: 539 CLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG--AFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 877 PCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFC----- 931
PC GASC + G + C C +G++G+ CE + C PN C C D + A C
Sbjct: 597 PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDKANCLCPDG 654
Query: 932 --DCLP---------------------GFRGTFCEEDINECASDPCRNGANCTDCVDSYT 968
C P G+ G CE ++ C S PC +G C Y
Sbjct: 655 SPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYN 714
Query: 969 CTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQ 1028
CTCP G++G C C C NGG+C + C CPP TG CQ + C S
Sbjct: 715 CTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA 774
Query: 1029 PCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVH-WCDSSPCKNGGKCWQTHTQYRCECPS 1087
PC +GGTC + G++ C C G+ GP C+ + C SPC+N C + RC CP+
Sbjct: 775 PCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPT 834
Query: 1088 GWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD 1147
G+TG C C AQ+ C C+ G + HC C G+TG C +
Sbjct: 835 GYTGGSCQTLMDLC---AQKP-------CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLS 884
Query: 1148 ECSP----------SPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGT 1197
C S C NG C D Y C C G+ G C + ++ C S PCQNG T
Sbjct: 885 SCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGAT 944
Query: 1198 CLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPP 1257
C+ P+ Y C C G G +C +D C +S C N+GTC + GG+ C CPP
Sbjct: 945 CMAQPSGYLCQCAPGYDGQNCSKELDAC--------QSQPCHNHGTCTPKPGGFHCACPP 996
Query: 1258 GFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
GFVG RCEGDV+ECL PC GT C N F+C+C GHTG+ CE I+ C +PC
Sbjct: 997 GFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF 1056
Query: 1318 NGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRS---PTCLC 1374
+GGTC + + GFIC CP GFEG TC + A +CG C +GG C+ P+ P C C
Sbjct: 1057 HGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCAC 1116
Query: 1375 LGPFTGPECQFP-ASSPCLGGNPCYNQGTCEPTSE--SPFYRCLCPAKFNGLLCHILDYS 1431
L + GP+C P A C +PC G+C T+ P +RC CP G C
Sbjct: 1117 LSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK---- 1172
Query: 1432 FGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCT 1491
G G C+ +G+ C C+ WDGGDCSL DPWK C
Sbjct: 1173 -PGAKG----------------CEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCP 1215
Query: 1492 QSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNS 1551
+CW F DG C QC+S CLFDG+DC+ C P YDQYC DHF +GHC++GCN+
Sbjct: 1216 SHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPA-CTPAYDQYCHDHFHNGHCEKGCNT 1274
Query: 1552 AECEWDGLDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAH 1611
AEC WDG DC + +L ++V++ P L F R LS L + ++D
Sbjct: 1275 AECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLRVGLWVRKDRD 1334
Query: 1612 GQQMIFPYYG-REEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMD 1670
G+ M++PY G R EE + AAP P G +E D +
Sbjct: 1335 GRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQ---------PLG-------KETDSLS 1378
Query: 1671 VRGSIVYLEIDNRQCV--QASSQCFQSATDVAAFLGALASLGSLN--IPYKIEAVQSETV 1726
G +V + +D +C +S+C + FL A+A++G+L +P + AV
Sbjct: 1379 A-GFVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAG 1437
Query: 1727 EPPPPAQLHFMYVAA-AAFVLLFFVGCGVLLS--RKRRRQHGQLWFPEGFKV---SEASK 1780
PP QL + + + A V+L +G ++L R+RRR+HG LW P GF ++++
Sbjct: 1438 TAPPANQLPWPVLCSPVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAP 1497
Query: 1781 KKRREPLGEDSVGLKPLKNAS----DGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDD 1836
+RR PLGEDS+GLK LK + DG +M E EE +
Sbjct: 1498 HRRRPPLGEDSIGLKALKPKAEVDEDGVVMCSGPEEG------------EEVGQAEETGP 1545
Query: 1837 QTDHRQWTQQHLDAADLRMSAMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLE 1896
+ + W+ A L +AM P + E++A D++ RGPDG TPLM A C G ++
Sbjct: 1546 PSTCQLWSLSGGCGA-LPQAAMLTPPQESEMEAP--DLDTRGPDGVTPLMSAVCCGE-VQ 1601
Query: 1897 TGNSEEEE-DAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADAN 1955
+G + P + GA T TGET LHLAAR+SR AA+RLLEA A+ N
Sbjct: 1602 SGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPN 1661
Query: 1956 IQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLI 2015
D GRTPLHAAV+ADA+ V Q+L+R+R T +DAR DGTTPL+LAARLAVE ++E+LI
Sbjct: 1662 QPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELI 1721
Query: 2016 NSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAREGSYE 2075
+ ADV A D GK+ALHWAAAVNN AA LL+ GA+KD Q+NRE+TPLFLAAREG+ E
Sbjct: 1722 AAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVE 1781
Query: 2076 TAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLD 2114
A++LL A R++ D P D+A +R H D++ LL+
Sbjct: 1782 VAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLLE 1820
Score = 1050 bits (2714), Expect = 0.0
Identities = 526/1366 (38%), Positives = 692/1366 (50%), Gaps = 133/1366 (9%)
Query: 2 PPLLAPLLCLALLPALAARGPR---CSQPGETCLNGGKCEAAN-GTEACVCGGAFVGPRC 57
PP L LL L LL ++ PR C E C NGG C + + G C C F+G C
Sbjct: 3 PPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
Query: 58 QDPNPCLSTP-CKNAGTCHVVDRRGVA----------DYACSCALGFSGPLCLTPLDNAC 106
Q P+PC + C+N G+C + + + C+C GF+G C L++ C
Sbjct: 63 QFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPC 122
Query: 107 LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166
+ C G C + +C C PGW+G+ CQ D C++NPC NGG CL CHC
Sbjct: 123 PPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHC 182
Query: 167 PPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSP 226
PP F G C +DVNEC Q PG C G +CHN +GS++C+C GP CE PC P
Sbjct: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG 242
Query: 227 CQNGGTCR--PTGDVT-HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRC 283
C NGGTC+ P D T H C C PGF G +CE N D+C + C+NGG C DG++TY C C
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
Query: 284 PPEWTGQYCTEDVDECQLM-PNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA 342
P WTG C+EDVDEC+ P C+NGGTC N+ G ++CVCV+GW G C EN+DDC +A
Sbjct: 303 PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA 362
Query: 343 ACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPS 402
C G+TC DRV SF C CP GRTGLLCHL D C+S PC+ + C TNP+ G +C C
Sbjct: 363 TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQP 422
Query: 403 GYTGPACSQDVDECSL---GANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSN 459
GY+GP C QD+DEC + G +PCEH G C+NT GSF C C GYTG RCE D NEC+S
Sbjct: 423 GYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQ 482
Query: 460 PCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTG 519
PC +TCLD + F C+C PG EG CEV T+ECAS+PCL++ C D +N FQC C G
Sbjct: 483 PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG 542
Query: 520 FTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG- 578
F+G C+ D+DEC S+PC NG +C D P + C C G+ G C+ ++DEC DPC G
Sbjct: 543 FSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGA 602
Query: 579 SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
SC D F CLC G+TG CE + C+ C+ C+D+ + C C G+ P C
Sbjct: 603 SCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDKANCLCPDGS--PGC 658
Query: 639 EINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGIN 698
D+C C G C C C+ G+TG C + C PC +GGTC +
Sbjct: 659 APPEDNCT---CHHGHC----QRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711
Query: 699 GFTCRCPEGYHDPTCLSEVNECNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNEC 757
G+ C CP GY PTC E+ C+S PC++ G+C S GY C C P +G C + + C
Sbjct: 712 GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC 771
Query: 758 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNIN-ECASNPCLNQGTCIDDVAGYKCN 816
S PC NGGTC + + C C GF GP C+ + CA +PC N+ TC D G +C
Sbjct: 772 VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCL 831
Query: 817 CLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC--- 873
C YTG +C+ ++ CA PC C Q+ SF C+C GW G C + ++ C
Sbjct: 832 CPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKA 889
Query: 874 -------VLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGI 926
V S C +G C ++ Y CHC G+ G C+ ++ C PC NG +C
Sbjct: 890 ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949
Query: 927 NTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPD 986
+ C C PG+ G C ++++ C S PC N CT + C CP GF G+ CE + +
Sbjct: 950 SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDE 1009
Query: 987 CTESSCFNGGT--CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGS-- 1042
C + C GT C N+F C C PG TG +C+ +++ C SQPC HGGTC+ GS
Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069
Query: 1043 -YRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHT---QYRCECPSGWTGLYCDVPS 1098
+ C CP+G+ GP C + C C +GG C + RC C SG+ G C P
Sbjct: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPP 1129
Query: 1099 VSCEVAAQRQGVDVARLCQHGGLCVD----AGNTHHCRCQAGYTGSYCEDLVDECSPSPC 1154
+G C + G C + G C C G C+ P
Sbjct: 1130 AP-------KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ--------KPG 1174
Query: 1155 QNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC-LDLPNTYKCSCPRGT 1213
G C G +C G N +GG C L +P+ +K CP +
Sbjct: 1175 AKG--CEGRSGDGACDAGCSGPGGN-------------WDGGDCSLGVPDPWK-GCPSHS 1218
Query: 1214 QGVHCEINVDD--CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNEC 1271
+ C + D C+P D S +C GY C PP
Sbjct: 1219 R---CWLLFRDGQCHPQCD----SEECL--------FDGYDCETPPA------------- 1250
Query: 1272 LSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
C Q C ++ HCE + C + G G C+
Sbjct: 1251 ----CTPAYDQYCHDHFHNGHCE-------KGCNTAECGWDGGDCR 1285
Score = 79.3 bits (194), Expect = 4e-14
Identities = 92/367 (25%), Positives = 124/367 (33%), Gaps = 124/367 (33%)
Query: 1303 RCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1362
R ++ G +PC NGGTC ++ + +G C+C GF G TC+ + C NGG+
Sbjct: 22 RPRGLLCGSFPEPCANGGTC-LSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGS 79
Query: 1363 C-------ISGPRSPT-------CLCLGPFTGPECQFPASSPC----------------- 1391
C + P SP+ C CL FTG CQ PC
Sbjct: 80 CQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG 139
Query: 1392 --------------------LGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYS 1431
NPC N G C T P +C CP F G C
Sbjct: 140 RPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLAT--YPQIQCHCPPGFEGHACE----- 192
Query: 1432 FGGGAGRDI------PPP----------------LIEEACELPECQEDAG---------N 1460
RD+ P P L E P C+ AG
Sbjct: 193 ------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNG 246
Query: 1461 KVCSLQCNN----HAC----GWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSA 1512
C L H C G+ G DC +N + NC S QC + G C ++
Sbjct: 247 GTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD----NCV-SHQCQ---NGGTCQDGLDTY 298
Query: 1513 GCL----FDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAEC----EWDGLDCAEH 1564
CL + G+DC +C +C+ + G C S C W G C E+
Sbjct: 299 TCLCPETWTGWDCSEDVDECETQGPPHCR---NGGTCQNSAGSFHCVCVSGWGGTSCEEN 355
Query: 1565 VPERLAA 1571
+ + +AA
Sbjct: 356 LDDCIAA 362
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 630 bits (1625), Expect = e-180
Identities = 352/1096 (32%), Positives = 517/1096 (47%), Gaps = 110/1096 (10%)
Query: 227 CQNGGTCRPTG-DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVD-----GVNTYN 280
C G C T+ C C P F+G+ C+E +D C CKN G+C++ Y
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKPCKNNGSCINKRENWDEQAYE 241
Query: 281 CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340
C C P +TG+ C+E + +CQ P+ C +G + T + C C ++G C + C
Sbjct: 242 CVCHPPFTGKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCV 299
Query: 341 SAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN-PCNEGSNCDTNPVNGKAICT 399
S + C + +++ ECP G + + + S PC G++C ++ +C
Sbjct: 300 SLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMCI 357
Query: 400 CPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC--V 457
C +T C C + P + C + C C+ G+T CE ++ C +
Sbjct: 358 CSPIFTDLLCKSIQTSCE--SFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLL 415
Query: 458 SNPCQNDATCLDQIGEFQCICMPGYEGVHCE-------VNTDECASSPCLHNGRCLDK-I 509
S C N+ C + IG F+ +C+PG C ++ C H G C DK
Sbjct: 416 SINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFH-GICQDKGP 474
Query: 510 NEFQCECPTGFTG---HLCQYDVD------------------------------ECASTP 536
+F+ GF G CQ +D E
Sbjct: 475 AQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEI 534
Query: 537 CKNGAKCLDGPNT--YTCVCTEGYTGT-HCEVDIDECDPDPCHYGSCKDGVATFTCLCRP 593
C NG CL ++ Y +C + G + E D+ + + H CKD + C C
Sbjct: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
Query: 594 GYTGHHCETNINEC-SSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDS 652
Y G C N++ C + G C + C L+ CEI+ +DC S+ C +
Sbjct: 595 SYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKN 654
Query: 653 GTCLDKIDGYECA-CEPGYTGSMCNINIDECAGNPCHNGGTCEDG--------------I 697
GT + GY C PG+ G+ C I+IDECA +PC NG TC D +
Sbjct: 655 GTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVV 714
Query: 698 NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNE 756
+GF+C C GY C ++++C N C H + C+D Y+C C W G C+ +NE
Sbjct: 715 DGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNE 774
Query: 757 CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
C+ NPC N TC D+ Y C C G++G NC INEC S+PC+N G C + +
Sbjct: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFV 834
Query: 817 CLLP--YTGATCEVVLAPC--APSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINE 872
CL P YTG C C +PCRN C D C+C ++G+ CE+D+ +
Sbjct: 835 CLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQH-CICREEFEGKNCEIDVKD 893
Query: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCD 932
C+ C+ C++ +RC C+ G+SG CE +I++C PC N G+C D N FC+
Sbjct: 894 CLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCN 953
Query: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC 992
C P + G FCE D+N+C PC + NC D Y C C G++GI+CE N +C C
Sbjct: 954 CEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPC 1013
Query: 993 FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT 1052
+ G C+DGIN +TC C GF G++C+ + N+C S PCLH G C + Y C+C T
Sbjct: 1014 LHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGT 1072
Query: 1053 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112
C+ ++ C S PC N G C ++ + C CP G+TG YC+ +C A+ + V
Sbjct: 1073 STQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNC---AEPELNSV 1129
Query: 1113 ARLCQHGGLCVDA-GNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKC 1171
+C +GG+CVD G+T CRC G++G +CE ++ECS SPC +GA C D++ GY CKC
Sbjct: 1130 --ICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKC 1187
Query: 1172 VAGYHGVNCSEEIDECLSHPC--------QNGGTCLDLPNTYKCSCPRGTQGVHC--EIN 1221
G+ G +C E+ EC+ + C + G TCL P CS G+ C EI
Sbjct: 1188 QPGWSGHHCENEL-ECIPNSCVHELCMENEPGSTCLCTPGFMTCSI-----GLLCGDEIR 1241
Query: 1222 VDDCNPPV----DPVS 1233
C P+ DP+S
Sbjct: 1242 RITCLTPIFQRTDPIS 1257
Score = 608 bits (1568), Expect = e-173
Identities = 356/1108 (32%), Positives = 494/1108 (44%), Gaps = 158/1108 (14%)
Query: 25 SQPGETCLNGGKC--EAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGV 82
S E C GKC EA + T +C C F G CQ+ + C PCKN G+C +++R
Sbjct: 177 SLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSC--INKREN 234
Query: 83 AD---YACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ 139
D Y C C F+G C + + C + C + G C +T + C C +SG C+
Sbjct: 235 WDEQAYECVCHPPFTGKNC-SEIIGQCQPHVCFH-GNCSNITSNSFICECDEQFSGPFCE 292
Query: 140 -QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNE 198
A PC S G C ++Y CP DV+E P C++G C
Sbjct: 293 VSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKI 350
Query: 199 VGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
C+C T C+ C P +N TC+ + + C+C+ GFT +NCE+ I
Sbjct: 351 SNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKC-EKDYPCSCISGFTEKNCEKAI 409
Query: 259 DDCP--GNNCKNGGACVDGVNTYNCRCPPEWT---------------------------- 288
D C NC N C + + + C P T
Sbjct: 410 DHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGIC 469
Query: 289 --------------------GQYCTEDVDECQLMPNACQNGGT-----------CHNTHG 317
G+ C +D + C T C H
Sbjct: 470 QDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHE 529
Query: 318 GYNCVCVNG-------------------WTGEDCSENIDDCASAACFHGATCHDRVASFY 358
G +C NG W G EN D C H A C D +
Sbjct: 530 GTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPR 589
Query: 359 CECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKAI-----CTCP--SGYTGPACS 410
C C G LC +N D C+ N + V+G + C C Y C
Sbjct: 590 CSCSLSYIGRLCVVNVDYCLGN--------HSISVHGLCLALSHNCNCSGLQRYERNICE 641
Query: 411 QDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQ 470
D ++C + C++ + G F +C+ G+ G +CEID++EC S+PC+N ATC+DQ
Sbjct: 642 IDTEDCKSAS--CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ 699
Query: 471 IGE--------------FQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCEC 516
G F C+C PGY G+ CE + D+C + C HN C D +QC C
Sbjct: 700 PGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVC 759
Query: 517 PTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC- 575
+ + G+ C+ + +EC PCKN + C D +Y C CT G+TG +C +I+ECD DPC
Sbjct: 760 LSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCM 819
Query: 576 HYGSCKDGV--ATFTCLCRPGYTGHHCETNINECS--SQPCRHGGTCQDR-DNAYLCFCL 630
+ G C + F CLC P YTG C N C PCR+ TC D C C
Sbjct: 820 NGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICR 879
Query: 631 KGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHN 689
+ G NCEI++ DC C D G C D ++ + C C PG++GS+C I I+EC+ PC N
Sbjct: 880 EEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKN 939
Query: 690 GGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV-HGACRDSLNGYKCDCDPGWSGT 748
GTC D N F C C YH P C +VN+C +PC+ C +GY C C PG++G
Sbjct: 940 NGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGI 999
Query: 749 NCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCID 808
NC+IN +EC S PC++ G C D + Y C C+ GF G +C+TN N+C SNPCL+ G C +
Sbjct: 1000 NCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH-GRCTE 1058
Query: 809 DVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEV 868
+ Y C+C T C++ + C PC N G C++S F+C+CP G+ G CE
Sbjct: 1059 LINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSA--HGFTCICPRGYTGAYCEK 1116
Query: 869 DINECVLSP-----CRHGASCQNTHG-GYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSC 922
I+ C C +G C + G + C C G+SG+ CE +I++C +PC +G C
Sbjct: 1117 SIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC 1176
Query: 923 TDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCEN 982
D IN C C PG+ G CE ++ EC + C + C + TC C GF
Sbjct: 1177 EDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVHEL-CMENEPGSTCLCTPGF------- 1227
Query: 983 NTPDCTESSCFNGGTCVDGINSFTCLCP 1010
+C G C D I TCL P
Sbjct: 1228 -------MTCSIGLLCGDEIRRITCLTP 1248
Score = 580 bits (1494), Expect = e-165
Identities = 342/1108 (30%), Positives = 502/1108 (45%), Gaps = 114/1108 (10%)
Query: 323 CVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCN 382
C + E CS + C S A +CH C+ P +G C DAC PC
Sbjct: 174 CQESLSSEFCSGH-GKCLSEAWSKTYSCH-------CQPPF--SGKYCQELDACSFKPCK 223
Query: 383 EGSNCDTNPVNGKAI---CTCPSGYTGPACSQDVDECSLGANPCEHAGKCIN-TLGSFEC 438
+C N C C +TG CS+ + +C + C H G C N T SF C
Sbjct: 224 NNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQ--PHVCFH-GNCSNITSNSFIC 280
Query: 439 QCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSP 498
+C + ++GP CE+ CVS C + + C G + E + E + P
Sbjct: 281 ECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP 340
Query: 499 CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGY 558
C + C+ N+ C C FT LC+ C S P +N A C Y C C G+
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 559 TGTHCEVDIDEC---DPDPCHYGSCKDGVATFTCLCRPGYTGHHC--ETNINECSSQPCR 613
T +CE ID C + + C + + F +C PG T + C N+ C
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCY 460
Query: 614 HG----GTCQDRDNAYLCFC----LKGTTGPNCEINLD-------DCASSP--------- 649
G G CQD+ A + G+ G C+ +D +C
Sbjct: 461 CGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDN 520
Query: 650 --------------CDSG-TCLDKIDG--YECACEPGYTGSMCNINIDECAGNPCHNGGT 692
C +G +CL + D Y C + G+M N + N C +
Sbjct: 521 NSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAV 580
Query: 693 CEDGINGFTCRCPEGYHDPTCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWSGTNC 750
C+D IN C C Y C+ V+ C N + VHG C + C + C
Sbjct: 581 CKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNIC 640
Query: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV 810
+I+ +C+S C NG T + + C GF G C+ +I+ECAS+PC N TCID
Sbjct: 641 EIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQP 700
Query: 811 AGYKCNCLLP--------------YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCV 856
Y C C+ P Y G CE + C + C + C+ + + S+ CV
Sbjct: 701 GNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCK--DLHLSYQCV 758
Query: 857 CPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPC 916
C + W+G CE + NEC ++PC++ ++C + + YRC C +G++G+NC +I++C +PC
Sbjct: 759 CLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPC 818
Query: 917 HNGGSCTDGI--NTAFCDCLPGFRGTFCEEDINEC--ASDPCRNGANCTDCVD-SYTCTC 971
NGG C + C C P + G FC + N C +PCRN + C VD + C C
Sbjct: 819 MNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCIC 878
Query: 972 PAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL 1031
F G +CE + DC SC + G C D +N+F C+C PGF+GS C+ ++NEC S+PC
Sbjct: 879 REEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCK 938
Query: 1032 HGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTG 1091
+ GTC D + C C Y GP C+ V+ C SPC + C Y C C G+TG
Sbjct: 939 NNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTG 998
Query: 1092 LYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 1151
+ C++ C ++ C H G+C+D N + C C++G+ G++CE ++C
Sbjct: 999 INCEINLDEC----------LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLS 1048
Query: 1152 SPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPR 1211
+PC +G CT+ + Y C C A C +I++C S PC N G C + + C CPR
Sbjct: 1049 NPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPR 1107
Query: 1212 GTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVG-GYSCTCPPGFVGERCEGDVNE 1270
G G +CE ++D+C +P S C N G CVD G + C C PGF G+ CE ++NE
Sbjct: 1108 GYTGAYCEKSIDNC---AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININE 1164
Query: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1330
C S+PC G +C +N + C+C+ G +G CE+ + C C + +
Sbjct: 1165 CSSSPC-LHGA-DCEDHINGYVCKCQPGWSGHHCENELE-CIPNSCVH----ELCMENEP 1217
Query: 1331 GFICKCPAGFE----GATCENDAR--TC 1352
G C C GF G C ++ R TC
Sbjct: 1218 GSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
Score = 515 bits (1327), Expect = e-145
Identities = 322/1089 (29%), Positives = 462/1089 (42%), Gaps = 183/1089 (16%)
Query: 492 DECASSPCLHNGRCLDKI--NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLD---- 545
+ +S C +G+CL + + C C F+G CQ ++D C+ PCKN C++
Sbjct: 176 ESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKREN 234
Query: 546 -GPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVA-TFTCLCRPGYTGHHCETN 603
Y CVC +TG +C I +C P C +G+C + + +F C C ++G CE +
Sbjct: 235 WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS 294
Query: 604 INECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT-CLDKIDGY 662
C S G C + +AY C KG++ N E ++ + + PC +GT C+ +
Sbjct: 295 AKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDV 354
Query: 663 ECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN- 721
C C P +T +C C P N TC+ + C C G+ + C ++ C
Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKL 414
Query: 722 -SNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNE--CESNPCVNG----GTCKDM-T 772
S C++ C + + +K C PG + C N + C G G C+D
Sbjct: 415 LSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGP 474
Query: 773 SGYVCTCREGFSGPN---CQTNINE---CASNPCLNQGTCIDDVAGYKCNCLLPYTGATC 826
+ + + GF+G CQ I+ A+N C T ++D +C P+ G T
Sbjct: 475 AQFEYVWQLGFAGSEGEKCQGVIDAYFFLAAN-CTEDATYVNDPEDNNSSCWFPHEG-TK 532
Query: 827 EVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQN 886
E+ C NG C ED + + +C W G + + + C+H A C++
Sbjct: 533 EI---------CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKD 583
Query: 887 THGGYRCHCQAGYSGRNC---------------------------------------ETD 907
RC C Y GR C E D
Sbjct: 584 EINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEID 643
Query: 908 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTD----- 962
+DC+ C NG + T F C+PGF+GT CE DI+ECAS PC+NGA C D
Sbjct: 644 TEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNY 703
Query: 963 ---------CVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF 1013
VD ++C C G+ GI CE + DC ++C + TC D S+ C+C +
Sbjct: 704 FCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDW 763
Query: 1014 TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGK 1073
G++C+ + NEC PC + TC D SYRC C G+TG NC ++ CDS PC NGG
Sbjct: 764 EGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGL 823
Query: 1074 CWQTHT--QYRCECPSGWTGLYCDVPSVSC---------------------------EVA 1104
C ++ Q+ C CP +TG +C C E
Sbjct: 824 CHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFE 883
Query: 1105 AQRQGVDVARL----CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC 1160
+ +DV CQ G C D N C C+ G++GS CE ++ECS PC+N TC
Sbjct: 884 GKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTC 943
Query: 1161 TDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEI 1220
D + C C YHG C ++++C PC + C+ + Y C C G G++CEI
Sbjct: 944 VDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEI 1003
Query: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPC---- 1276
N+D+C S C ++G C+D + Y+C C GF G CE + N+CLSNPC
Sbjct: 1004 NLDEC--------LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR 1055
Query: 1277 ------------DARGTQN-CVQRVND------------------FHCECRAGHTGRRCE 1305
DA GT C ++ND F C C G+TG CE
Sbjct: 1056 CTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCE 1115
Query: 1306 SVINGCKGKP-----CKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNG 1360
I+ C C NGG C F C+C GF G CE + C S CL+G
Sbjct: 1116 KSIDNCAEPELNSVICLNGGICV--DGPGHTFDCRCLPGFSGQFCEININECSSSPCLHG 1173
Query: 1361 GTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKF 1420
C C C ++G C+ C+ N C ++ E P CLC F
Sbjct: 1174 ADCEDHINGYVCKCQPGWSGHHCE--NELECI-PNSCVHELCME---NEPGSTCLCTPGF 1227
Query: 1421 N----GLLC 1425
GLLC
Sbjct: 1228 MTCSIGLLC 1236
Score = 436 bits (1122), Expect = e-121
Identities = 308/1134 (27%), Positives = 452/1134 (39%), Gaps = 214/1134 (18%)
Query: 560 GTHCEVDIDECDPDPCHYGS----------CKDGVA-----------------TFTCLCR 592
GTH + + P PC G C++ ++ T++C C+
Sbjct: 144 GTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQ 203
Query: 593 PGYTGHHCETNINECSSQPCRHGGTCQDR-----DNAYLCFCLKGTTGPNCEINLDDCAS 647
P ++G +C+ ++ CS +PC++ G+C ++ + AY C C TG NC + C
Sbjct: 204 PPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQP 262
Query: 648 SPCDSGTCLD-KIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPE 706
C G C + + + C C+ ++G C ++ C G C + + +T CP+
Sbjct: 263 HVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPK 322
Query: 707 GYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNG 765
G ++V+E + PC +G C N C C P ++ C CES P N
Sbjct: 323 GSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNN 382
Query: 766 GTCKDMTSGYVCTCREGFSGPNCQTNINECA--SNPCLNQGTCIDDVAGYKCNCL----- 818
TCK Y C+C GF+ NC+ I+ C S CLN+ C + + +K C+
Sbjct: 383 ATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTK 442
Query: 819 ---------------LPYTGATCEVVLAPCAPSPCR----------NGGECRQSED-YES 852
L Y G T + P+ G +C+ D Y
Sbjct: 443 NPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFF 502
Query: 853 FSCVCPTGWQGQTCEVDINECVLSP-------CRHGASCQNTHGG--YRCHCQAGYSGRN 903
+ C D N P C +G SC + YR C ++G
Sbjct: 503 LAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNM 562
Query: 904 CETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC 963
+ D + N C + C D IN C C + G C +++ C + +
Sbjct: 563 YLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLA 622
Query: 964 VDSYTCTCPAGFSGIH------CENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSY 1017
+ S+ C C SG+ CE +T DC +SC NG T F C PGF G+
Sbjct: 623 L-SHNCNC----SGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQ 677
Query: 1018 CQHDVNECDSQPCLHGGTCQDGCGSY--------------RCTCPQGYTGPNCQNLVHWC 1063
C+ D++EC S PC +G TC D G+Y C C GY G C+ + C
Sbjct: 678 CEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDC 737
Query: 1064 DSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCV 1123
+ C++ C H Y+C C S W G +C+ S C++ C++ C
Sbjct: 738 ILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNP----------CKNNSTCT 787
Query: 1124 DAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYL--GGYSCKCVAGYHGVNCS 1181
D ++ C C +G+TG C + ++EC PC NG C + G + C C Y G C
Sbjct: 788 DLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCH 847
Query: 1182 EEIDEC--LSHPCQNGGTCLDLPNTYK-CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC 1238
+ + C L +PC+N TCL L + + C C +G +CEI+V DC C
Sbjct: 848 QRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC--------LFLSC 899
Query: 1239 FNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
+ G C D V + C C PGF G CE ++NEC S PC GT CV N F C C
Sbjct: 900 QDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGT--CVDLTNRFFCNCEPE 957
Query: 1299 HTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCL 1358
+ G CE +N CK PC + C ++ G+ C C G+ G CE + C S CL
Sbjct: 958 YHGPFCELDVNKCKISPCLDEENCVYRTD---GYNCLCAPGYTGINCEINLDECLSEPCL 1014
Query: 1359 NGGTCISGPRSPTCLCLGPFTGPECQFPA----SSPCLGGN------------------- 1395
+ G CI G TC C F G C+ A S+PCL G
Sbjct: 1015 HDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTST 1074
Query: 1396 ------------PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPP 1443
PC N+G C+ ++ + C+CP + G C
Sbjct: 1075 QCKIKINDCTSIPCMNEGFCQKSAHG--FTCICPRGYTGAYCE----------------- 1115
Query: 1444 LIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDG 1503
+ C E N V L +GG C + P T +C FS
Sbjct: 1116 -----KSIDNCAEPELNSVICL---------NGGIC---VDGP--GHTFDCRCLPGFSGQ 1156
Query: 1504 HCD---SQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAEC 1554
C+ ++C+S+ CL G DC E N Y C+ +S HC+ N EC
Sbjct: 1157 FCEININECSSSPCL-HGADC---EDHING-YVCKCQPGWSGHHCE---NELEC 1202
Score = 73.6 bits (179), Expect = 2e-12
Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 894 HCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINEC--AS 951
H AG S C C C NGG+C + + +C+C G++G+FC E ++ C
Sbjct: 2599 HPNAGRSVGQCHAS--PCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH 2656
Query: 952 DP---CRNGANCTDCVDSYTCTCPAGFSGIHCE 981
DP C GA C YTC CP G +GI+CE
Sbjct: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 70.9 bits (172), Expect = 2e-11
Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 10/84 (11%)
Query: 1146 VDECSPSPCQ-----NGATCTDYLGGYSCKCVAGYHGVNCSEEIDEC-----LSHPCQNG 1195
V +C SPC NG TC + C C G+ G C+E + C H C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 1196 GTCLDLPNTYKCSCPRGTQGVHCE 1219
TC+ LP+ Y C CP GT G++CE
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 66.6 bits (161), Expect = 3e-10
Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
Query: 1048 PQGYTGPNCQNLVHWCDSSPCK-----NGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE 1102
P+G+ PN V C +SPC NGG C ++ T C C +GW G +C +C+
Sbjct: 2596 PEGH--PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD 2653
Query: 1103 VAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPS 1152
D C G C+ + + C C G TG YCE + PS
Sbjct: 2654 PEH-----DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 66.2 bits (160), Expect = 4e-10
Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Query: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPS-----PCQNGATCTDYLGGYSCK 1170
C +GG C+++G + +C C G+ GS+C + V C P C GATC GY+C
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
Query: 1171 CVAGYHGVNCSEEI 1184
C G G+ C + +
Sbjct: 2679 CPLGTTGIYCEQAL 2692
Score = 65.9 bits (159), Expect = 5e-10
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 1179 NCSEEIDECLSHPCQ-----NGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVS 1233
N + +C + PC NGGTC++ + C+C G +G C V C+P DP
Sbjct: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
Query: 1234 RSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
C TC+ GY+C CP G G CE
Sbjct: 2661 H---CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 65.1 bits (157), Expect = 9e-10
Identities = 82/342 (23%), Positives = 124/342 (36%), Gaps = 69/342 (20%)
Query: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQ-----PCLHGGTCQDGCG 1041
C+ C NGGTC++ S C C G+ GS+C V+ CD + C G TC
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 1042 SYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCW----------QTHTQ----------- 1080
Y C CP G TG C+ + D S ++ W +TH Q
Sbjct: 2674 GYTCFCPLGTTGIYCEQALSISDPS-FRSNELSWMSFASFHVRKKTHIQLQFQPLAADGI 2732
Query: 1081 --YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
Y + +G + + V+ V + D + + G+T H +AG
Sbjct: 2733 LFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHI-IKAGRV 2791
Query: 1139 GS--YCE----DLVDECSPSPCQNGATCTDYLGGYSCKCV----------AGYHG----- 1177
G+ Y + ++ ++ S Y+GG S + G+ G
Sbjct: 2792 GAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQV 2851
Query: 1178 -VNCSE-EIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD----CNP--PV 1229
+N E ++ E + N G C + C G C +N C P
Sbjct: 2852 IINNQELQLTEFGAKGGSNVGDC----DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAG 2907
Query: 1230 DPVSRSPKCFNN-----GTCV-DQVGGYSCTCPPGFVGERCE 1265
+ ++S C NN C+ DQ YSC C G+VG CE
Sbjct: 2908 NTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 64.7 bits (156), Expect = 1e-09
Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 257 NIDDCPG-----NNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGT 311
N+ DC G N C+NGG C T++CRC P+W G C + V + N C +
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV---SCLNNLCLHQSL 2926
Query: 312 C-HNTHGGYNCVCVNGWTGEDC 332
C + Y+C+C GW G C
Sbjct: 2927 CIPDQSFSYSCLCTLGWVGRYC 2948
Score = 63.5 bits (153), Expect = 2e-09
Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 25/130 (19%)
Query: 936 GFRGTFCEEDINE---CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC 992
GFRG + +N D R+G N +C + P C C
Sbjct: 2304 GFRGCILDLQVNNKEFFIIDEARHGKNIENC-------------------HVPWCAHHLC 2344
Query: 993 FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGS-YRCTCPQGY 1051
N GTC+ + C CP ++G CQ C++ PC +G TC G+ C CP G
Sbjct: 2345 RNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYGR 2402
Query: 1052 TGPNCQNLVH 1061
+GP C + ++
Sbjct: 2403 SGPLCTDAIN 2412
Score = 63.5 bits (153), Expect = 2e-09
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 261 CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQL---MPNACQNGGTCHNTHG 317
C C NGG C++ + C C W G +CTE V C P+ C G TC +
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 318 GYNCVCVNGWTGEDCSE 334
GY C C G TG C +
Sbjct: 2674 GYTCFCPLGTTGIYCEQ 2690
Score = 63.2 bits (152), Expect = 3e-09
Identities = 41/128 (32%), Positives = 56/128 (43%), Gaps = 17/128 (13%)
Query: 858 PTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCH 917
P G+QG +V IN L GA + G + D C N C
Sbjct: 2841 PVGFQGCIRQVIINNQELQLTEFGAKGGSNVG---------------DCDGTACGYNTCR 2885
Query: 918 NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC-TDCVDSYTCTCPAGFS 976
NGG CT T C CLP + G C + ++ C ++ C + + C D SY+C C G+
Sbjct: 2886 NGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWV 2944
Query: 977 GIHCENNT 984
G +CEN T
Sbjct: 2945 GRYCENKT 2952
Score = 62.8 bits (151), Expect = 4e-09
Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 105 ACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEA-SYI 163
AC N CRNGG C + T + CRC P W+G +C Q+ C +N C + C+P ++ SY
Sbjct: 2878 ACGYNTCRNGGECTV-NGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYS 2936
Query: 164 CHCPPSFHGPTC 175
C C + G C
Sbjct: 2937 CLCTLGWVGRYC 2948
Score = 62.0 bits (149), Expect = 7e-09
Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEAS-YIC 164
C + CRN GTC + C CP +SGK CQ A C +NPC NG C+P + +C
Sbjct: 2339 CAHHLCRNNGTC-ISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPKSGTDIVC 2396
Query: 165 HCPPSFHGPTCRQDVN 180
CP GP C +N
Sbjct: 2397 LCPYGRSGPLCTDAIN 2412
Score = 62.0 bits (149), Expect = 7e-09
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 6/79 (7%)
Query: 221 PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDC-----PGNNCKNGGACVDG 275
PCS C NGGTC +G + C C G+ G C E + C P ++C G C+
Sbjct: 2613 PCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
Query: 276 VNTYNCRCPPEWTGQYCTE 294
+ Y C CP TG YC +
Sbjct: 2672 PHGYTCFCPLGTTGIYCEQ 2690
Score = 60.8 bits (146), Expect = 2e-08
Identities = 30/90 (33%), Positives = 40/90 (44%), Gaps = 10/90 (11%)
Query: 493 ECASSPCL-----HNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTP-----CKNGAK 542
+C +SPC + G C++ C C TG+ G C V C C GA
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 543 CLDGPNTYTCVCTEGYTGTHCEVDIDECDP 572
C+ P+ YTC C G TG +CE + DP
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
Score = 59.3 bits (142), Expect = 5e-08
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Query: 392 VNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEI 451
+N + + G G + D D + G N C + G+C +F C+CL + G C
Sbjct: 2853 INNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ 2912
Query: 452 DVNECVSNPCQNDATCL-DQIGEFQCICMPGYEGVHCEVNT 491
V+ C++N C + + C+ DQ + C+C G+ G +CE T
Sbjct: 2913 SVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKT 2952
Score = 58.9 bits (141), Expect = 6e-08
Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNT-YTC 552
CA C +NG C+ CECP ++G LCQ+ C + PC NGA C+ T C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVC 2396
Query: 553 VCTEGYTGTHCEVDIDECDP 572
+C G +G C I+ P
Sbjct: 2397 LCPYGRSGPLCTDAINITQP 2416
Score = 58.5 bits (140), Expect = 8e-08
Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 134 SGKSCQQ--ADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK---PGL 188
+G+S Q A PC+ C NGG C+ S C+C + G C + V+ C + P
Sbjct: 2602 AGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH 2661
Query: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPS 225
C G TC + Y C C TG CE+ PS
Sbjct: 2662 CSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 58.5 bits (140), Expect = 8e-08
Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 946 INECASDPCR-----NGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTES-----SCFNG 995
+ +C + PC NG C + S C C G+ G C C C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 996 GTCVDGINSFTCLCPPGFTGSYCQHDVNECD 1026
TC+ + +TC CP G TG YC+ ++ D
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISD 2696
Score = 58.5 bits (140), Expect = 8e-08
Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 299 CQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC-----ASAACFHGATCHDR 353
C LM C NGGTC + C C GW G C+E + C C GATC
Sbjct: 2614 CSLMK--CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
Query: 354 VASFYCECPHGRTGLLC 370
+ C CP G TG+ C
Sbjct: 2672 PHGYTCFCPLGTTGIYC 2688
Score = 58.5 bits (140), Expect = 8e-08
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 12/83 (14%)
Query: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
C + C+NGG+C T + C C W G C+ SVSC + LC H LC
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSC----------LNNLCLHQSLC 2927
Query: 1123 V-DAGNTHHCRCQAGYTGSYCED 1144
+ D ++ C C G+ G YCE+
Sbjct: 2928 IPDQSFSYSCLCTLGWVGRYCEN 2950
Score = 58.5 bits (140), Expect = 8e-08
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACV-DGVNTYN 280
C + C+NGG C G T C CLP + G C +++ C N C + C+ D +Y+
Sbjct: 2879 CGYNTCRNGGECTVNG-TTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYS 2936
Query: 281 CRCPPEWTGQYC 292
C C W G+YC
Sbjct: 2937 CLCTLGWVGRYC 2948
Score = 58.2 bits (139), Expect = 1e-07
Identities = 33/92 (35%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 780 REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
R G + NC ++ CA + C N GTCI D C C Y+G C+ A C +PC
Sbjct: 2326 RHGKNIENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCG 2381
Query: 840 NGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 871
NG C + C+CP G G C IN
Sbjct: 2382 NGATCVPKSGTD-IVCLCPYGRSGPLCTDAIN 2412
Score = 57.8 bits (138), Expect = 1e-07
Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 10/84 (11%)
Query: 1022 VNECDSQPCL-----HGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSS-----PCKNG 1071
V +C + PC +GGTC + S C C G+ G C V CD C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 1072 GKCWQTHTQYRCECPSGWTGLYCD 1095
C Y C CP G TG+YC+
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 57.4 bits (137), Expect = 2e-07
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP-----CRHGASCQ 885
+PC+ C NGG C +S S C C TGW+G C ++ C C GA+C
Sbjct: 2612 SPCSLMKCGNGGTCIESGT--SVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCI 2669
Query: 886 NTHGGYRCHCQAGYSGRNCETDIDDCRPN 914
+ GY C C G +G CE + P+
Sbjct: 2670 SLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 57.0 bits (136), Expect = 2e-07
Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
Query: 330 EDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDT 389
E+C ++ CA C + TC + +CECP +G LC +C +NPC G+ C
Sbjct: 2332 ENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF-ASCENNPCGNGATC-- 2386
Query: 390 NPVNG-KAICTCPSGYTGPACSQDVD 414
P +G +C CP G +GP C+ ++
Sbjct: 2387 VPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 57.0 bits (136), Expect = 2e-07
Identities = 39/128 (30%), Positives = 52/128 (40%), Gaps = 25/128 (19%)
Query: 936 GFRGTFCEEDIN----ECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS 991
GF+G + IN + + G+N DC G C NT
Sbjct: 2843 GFQGCIRQVIINNQELQLTEFGAKGGSNVGDC------------DGTACGYNT------- 2883
Query: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTC-QDGCGSYRCTCPQG 1050
C NGG C +F+C C P + G+ C V+ C + CLH C D SY C C G
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
Query: 1051 YTGPNCQN 1058
+ G C+N
Sbjct: 2943 WVGRYCEN 2950
Score = 57.0 bits (136), Expect = 2e-07
Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV 810
D + C N C NGG C + + C C ++G C +++ C +N CL+Q CI D
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQ 2931
Query: 811 A-GYKCNCLLPYTGATCE 827
+ Y C C L + G CE
Sbjct: 2932 SFSYSCLCTLGWVGRYCE 2949
Score = 55.8 bits (133), Expect = 5e-07
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 11/84 (13%)
Query: 529 VDECASTPCK-----NGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP--DPCHY---- 577
V +C ++PC NG C++ + C CT G+ G+ C + CDP DP H+
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 578 GSCKDGVATFTCLCRPGYTGHHCE 601
+C +TC C G TG +CE
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 55.8 bits (133), Expect = 5e-07
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 4/74 (5%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASC-QNTHGGY 891
C + CRNGGEC + + +FSC C W G TC ++ C+ + C H + C + Y
Sbjct: 2879 CGYNTCRNGGEC--TVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSY 2935
Query: 892 RCHCQAGYSGRNCE 905
C C G+ GR CE
Sbjct: 2936 SCLCTLGWVGRYCE 2949
Score = 55.5 bits (132), Expect = 7e-07
Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 13/96 (13%)
Query: 705 PEGYHDPTCLSEVNECNSNPCV------HGACRDSLNGYKCDCDPGWSGTNCDINNNEC- 757
PEG+ P V +C+++PC G C +S C+C GW G+ C + C
Sbjct: 2596 PEGH--PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD 2653
Query: 758 -ESNP---CVNGGTCKDMTSGYVCTCREGFSGPNCQ 789
E +P C G TC + GY C C G +G C+
Sbjct: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 55.5 bits (132), Expect = 7e-07
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 10/91 (10%)
Query: 756 ECESNPCV-----NGGTCKDMTSGYVCTCREGFSGPNCQTNINEC-----ASNPCLNQGT 805
+C ++PC NGGTC + + C C G+ G C ++ C + C T
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 806 CIDDVAGYKCNCLLPYTGATCEVVLAPCAPS 836
CI GY C C L TG CE L+ PS
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 54.3 bits (129), Expect = 2e-06
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 33/129 (25%)
Query: 860 GWQGQTCEVDINE---CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPC 916
G++G ++ +N ++ RHG + +N H + C + C
Sbjct: 2304 GFRGCILDLQVNNKEFFIIDEARHGKNIENCH-------------------VPWCAHHLC 2344
Query: 917 HNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC-----TDCVDSYTCTC 971
N G+C FC+C + G C+ C ++PC NGA C TD V C C
Sbjct: 2345 RNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIV----CLC 2398
Query: 972 PAGFSGIHC 980
P G SG C
Sbjct: 2399 PYGRSGPLC 2407
Score = 53.5 bits (127), Expect = 3e-06
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 8/81 (9%)
Query: 566 DIDECDPDPCHYGSCKDGV------ATFTCLCRPGYTGHHCETNINECSSQPCRHGGTC- 618
++ +CD C Y +C++G TF+C C P + G+ C +++ C + C H C
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
Query: 619 QDRDNAYLCFCLKGTTGPNCE 639
D+ +Y C C G G CE
Sbjct: 2929 PDQSFSYSCLCTLGWVGRYCE 2949
Score = 52.8 bits (125), Expect = 4e-06
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 637 NCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTC-- 693
NC + CA C ++GTC+ + C C Y+G +C C NPC NG TC
Sbjct: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVP 2388
Query: 694 EDGINGFTCRCPEGYHDPTCLSEVN 718
+ G + C CP G P C +N
Sbjct: 2389 KSGTD-IVCLCPYGRSGPLCTDAIN 2412
Score = 52.8 bits (125), Expect = 4e-06
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 7/98 (7%)
Query: 120 LTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDV 179
L LTE+ + G S C N C NGG+C ++ C C P + G TC Q V
Sbjct: 2858 LQLTEFGAK---GGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV 2914
Query: 180 NECGQKPGLCRHGGTC-HNEVGSYRCVCRATHTGPNCE 216
+ LC H C ++ SY C+C G CE
Sbjct: 2915 SCLN---NLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 52.4 bits (124), Expect = 6e-06
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
Query: 786 PNCQTNINECASNPCL-----NQGTCIDDVAGYKCNCLLPYTGATCEVVLAPC-----AP 835
PN ++ +C ++PC N GTCI+ CNC + G+ C ++ C P
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 836 SPCRNGGECRQSEDYESFSCVCPTGWQGQTCE 867
C G C ++C CP G G CE
Sbjct: 2660 HHCSRGATCISLP--HGYTCFCPLGTTGIYCE 2689
Score = 52.0 bits (123), Expect = 7e-06
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 9/89 (10%)
Query: 706 EGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNG 765
E H P C + C +N G C C+C +SG C + CE+NPC NG
Sbjct: 2332 ENCHVPWCAHHL--CRNN----GTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNG 2383
Query: 766 GTCKDMT-SGYVCTCREGFSGPNCQTNIN 793
TC + + VC C G SGP C IN
Sbjct: 2384 ATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 52.0 bits (123), Expect = 7e-06
Identities = 29/74 (39%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 1352 CGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPF 1411
C C N GTCIS + C C ++G CQF + NPC N TC P S +
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCE----NNPCGNGATCVPKSGTDI 2394
Query: 1412 YRCLCPAKFNGLLC 1425
CLCP +G LC
Sbjct: 2395 V-CLCPYGRSGPLC 2407
Score = 52.0 bits (123), Expect = 7e-06
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 11/83 (13%)
Query: 636 PNCEINLDDCASSPC------DSGTCLDKIDGYECACEPGYTGSMCNINIDEC-----AG 684
PN ++ C +SPC + GTC++ C C G+ GS C + C
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 685 NPCHNGGTCEDGINGFTCRCPEG 707
+ C G TC +G+TC CP G
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLG 2682
Score = 52.0 bits (123), Expect = 7e-06
Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 1297 AGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR 1356
AG + +C + + C C NGGTC + S T+ C C G++G+ C TC
Sbjct: 2602 AGRSVGQCHA--SPCSLMKCGNGGTC-IESGTS--VYCNCTTGWKGSFCTETVSTCDPEH 2656
Query: 1357 -----CLNGGTCISGPRSPTCLCLGPFTGPECQ 1384
C G TCIS P TC C TG C+
Sbjct: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 52.0 bits (123), Expect = 7e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 11/84 (13%)
Query: 567 IDECDPDPCHY------GSCKDGVATFTCLCRPGYTGHHCETNINECSSQP-----CRHG 615
+ +C PC G+C + + C C G+ G C ++ C + C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 616 GTCQDRDNAYLCFCLKGTTGPNCE 639
TC + Y CFC GTTG CE
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 52.0 bits (123), Expect = 7e-06
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFS 854
C N C N G C + + C CL + G TC ++ C + C + C + + S+S
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSF-SYS 2936
Query: 855 CVCPTGWQGQTCE 867
C+C GW G+ CE
Sbjct: 2937 CLCTLGWVGRYCE 2949
Score = 51.6 bits (122), Expect = 1e-05
Identities = 30/79 (37%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 63 CLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTL 122
C C+N GTC + D + C C +SG LC +C NPC NG TC +
Sbjct: 2339 CAHHLCRNNGTC-ISDNENLF---CECPRLYSGKLCQFA---SCENNPCGNGATCVPKSG 2391
Query: 123 TEYKCRCPPGWSGKSCQQA 141
T+ C CP G SG C A
Sbjct: 2392 TDIVCLCPYGRSGPLCTDA 2410
Score = 51.6 bits (122), Expect = 1e-05
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLP 247
LCR+ GTC ++ + C C ++G C+ + C +PC NG TC P C C
Sbjct: 2343 LCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPY 2400
Query: 248 GFTGQNCEENID 259
G +G C + I+
Sbjct: 2401 GRSGPLCTDAIN 2412
Score = 51.6 bits (122), Expect = 1e-05
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 672 GSMCNINIDECAG-----NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV 726
G+ N+ +C G N C NGG C F+CRC + TC V+ C +N C+
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCL 2922
Query: 727 HGA--CRDSLNGYKCDCDPGWSGTNCD 751
H + D Y C C GW G C+
Sbjct: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 51.2 bits (121), Expect = 1e-05
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 12/96 (12%)
Query: 1176 HGVNCSE-EIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSR 1234
HG N + C H C+N GTC+ C CPR G C+ + NP
Sbjct: 2327 HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNP------- 2379
Query: 1235 SPKCFNNGTCVDQVG-GYSCTCPPGFVGERCEGDVN 1269
C N TCV + G C CP G G C +N
Sbjct: 2380 ---CGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 50.1 bits (118), Expect = 3e-05
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1330
C + C GT C+ + CEC ++G+ C+ C+ PC NG TC S T
Sbjct: 2339 CAHHLCRNNGT--CISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGT-- 2392
Query: 1331 GFICKCPAGFEGATC 1345
+C CP G G C
Sbjct: 2393 DIVCLCPYGRSGPLC 2407
Score = 50.1 bits (118), Expect = 3e-05
Identities = 34/111 (30%), Positives = 51/111 (45%), Gaps = 10/111 (9%)
Query: 1280 GTQNCVQRVNDFHCECRAGHTGRRCESVINGCKG-----KPCKNGGTCAVASNTARGFIC 1334
G Q C+++V + E + G + S + C G C+NGG C V T F C
Sbjct: 2843 GFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTT---FSC 2899
Query: 1335 KCPAGFEGATCENDARTCGSLRCLNGGTCISGPR-SPTCLCLGPFTGPECQ 1384
+C + G TC N + +C + CL+ CI S +CLC + G C+
Sbjct: 2900 RCLPDWAGNTC-NQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 50.1 bits (118), Expect = 3e-05
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 304 NACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC-HDRVASFYCECP 362
N C+NGG C ++C C+ W G C++++ C + C H + C D+ S+ C C
Sbjct: 2882 NTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCT 2940
Query: 363 HGRTGLLC 370
G G C
Sbjct: 2941 LGWVGRYC 2948
Score = 49.3 bits (116), Expect = 5e-05
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 14/101 (13%)
Query: 1053 GPNCQNL-VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVD 1111
G N +N V WC C+N G C + CECP ++G C SCE
Sbjct: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCE--------- 2376
Query: 1112 VARLCQHGGLCV-DAGNTHHCRCQAGYTGSYCEDLVDECSP 1151
C +G CV +G C C G +G C D ++ P
Sbjct: 2377 -NNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
Score = 49.3 bits (116), Expect = 5e-05
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCL-DGPNTYTC 552
C + C + G C F C C + G+ C V C + C + + C+ D +Y+C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 553 VCTEGYTGTHCE 564
+CT G+ G +CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 48.9 bits (115), Expect = 6e-05
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1115 LCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLG-GYSCKCVA 1173
LC++ G C+ C C Y+G C+ C +PC NGATC G C C
Sbjct: 2343 LCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPY 2400
Query: 1174 GYHGVNCSEEID 1185
G G C++ I+
Sbjct: 2401 GRSGPLCTDAIN 2412
Score = 48.9 bits (115), Expect = 6e-05
Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 7/84 (8%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
C N G C + N C C + G CQ + C + PC N TC V + G D C C
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATC--VPKSG-TDIVCLCP 2399
Query: 91 LGFSGPLCLTPLDNACLTNPCRNG 114
G SGPLC ++ +T P +G
Sbjct: 2400 YGRSGPLCTDAIN---ITQPRFSG 2420
Score = 48.1 bits (113), Expect = 1e-04
Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Query: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIG-EFQCICMPG 481
C + G CI+ + C+C + Y+G C+ C +NPC N ATC+ + G + C+C G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
Query: 482 YEGVHC 487
G C
Sbjct: 2402 RSGPLC 2407
Score = 47.8 bits (112), Expect = 1e-04
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 401 PSGYTGPACSQDVDECSLGANPCE-----HAGKCINTLGSFECQCLQGYTGPRCEIDVNE 455
P G+ P + V +C A+PC + G CI + S C C G+ G C V+
Sbjct: 2596 PEGH--PNAGRSVGQCH--ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVST 2651
Query: 456 C-----VSNPCQNDATCLDQIGEFQCICMPGYEGVHCE 488
C + C ATC+ + C C G G++CE
Sbjct: 2652 CDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 47.4 bits (111), Expect = 2e-04
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSC-KDGVAT 586
D C C+NG +C T++C C + G C + + H C D +
Sbjct: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFS 2934
Query: 587 FTCLCRPGYTGHHCE 601
++CLC G+ G +CE
Sbjct: 2935 YSCLCTLGWVGRYCE 2949
Score = 46.6 bits (109), Expect = 3e-04
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNT-YKC 1207
C+ C+N TC C+C Y G C + C ++PC NG TC+ T C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
Query: 1208 SCPRGTQGVHCEINVDDCNP 1227
CP G G C ++ P
Sbjct: 2397 LCPYGRSGPLCTDAINITQP 2416
Score = 46.6 bits (109), Expect = 3e-04
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Query: 757 CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
C + C N GTC C C +SG CQ C +NPC N TC+ +G
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPK-SGTDIV 2395
Query: 817 CLLPY--TGATC 826
CL PY +G C
Sbjct: 2396 CLCPYGRSGPLC 2407
Score = 46.6 bits (109), Expect = 3e-04
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 11/87 (12%)
Query: 1268 VNECLSNPCDARGTQN---CVQRVNDFHCECRAGHTGRRCESVINGCKGK-----PCKNG 1319
V +C ++PC N C++ +C C G G C ++ C + C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 1320 GTCAVASNTARGFICKCPAGFEGATCE 1346
TC + G+ C CP G G CE
Sbjct: 2666 ATCI---SLPHGYTCFCPLGTTGIYCE 2689
Score = 46.6 bits (109), Expect = 3e-04
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDC-----ASSPCDSG-T 654
+ + + CS C +GGTC + + C C G G C + C C G T
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 655 CLDKIDGYECACEPGYTGSMC 675
C+ GY C C G TG C
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYC 2688
Score = 46.2 bits (108), Expect = 4e-04
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 251 GQNCEE-NIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNG 309
G+N E ++ C + C+N G C+ C CP ++G+ C C+ N C NG
Sbjct: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCE--NNPCGNG 2383
Query: 310 GTCHNTHG-GYNCVCVNGWTGEDCSENID 337
TC G C+C G +G C++ I+
Sbjct: 2384 ATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 46.2 bits (108), Expect = 4e-04
Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 676 NINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLN 735
N ++ CA + C N GTC C CP Y C + C +NPC +GA +
Sbjct: 2333 NCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKS 2390
Query: 736 G--YKCDCDPGWSGTNC 750
G C C G SG C
Sbjct: 2391 GTDIVCLCPYGRSGPLC 2407
Score = 46.2 bits (108), Expect = 4e-04
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 7/86 (8%)
Query: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDC-----RPNPCHNGGSCTDGIN 927
C L C +G +C + C+C G+ G C + C P+ C G +C +
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 928 TAFCDCLPGFRGTFCEEDINECASDP 953
C C G G +CE+ ++ SDP
Sbjct: 2674 GYTCFCPLGTTGIYCEQALS--ISDP 2697
Score = 46.2 bits (108), Expect = 4e-04
Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
Query: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTS 1407
D CG C NGG C + +C CL + G C S CL N C +Q C P
Sbjct: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN--QSVSCL-NNLCLHQSLCIP-D 2930
Query: 1408 ESPFYRCLCPAKFNGLLC 1425
+S Y CLC + G C
Sbjct: 2931 QSFSYSCLCTLGWVGRYC 2948
Score = 45.8 bits (107), Expect = 5e-04
Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 11/85 (12%)
Query: 678 NIDECAGNPCH-----NGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN-----SNPCVH 727
++ +C +PC NGGTC + C C G+ C V+ C+ + C
Sbjct: 2605 SVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
Query: 728 GA-CRDSLNGYKCDCDPGWSGTNCD 751
GA C +GY C C G +G C+
Sbjct: 2665 GATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 45.1 bits (105), Expect = 0.001
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKI-NEFQC 514
C + C+N+ TC+ C C Y G C+ + C ++PC + C+ K + C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVC 2396
Query: 515 ECPTGFTGHLC 525
CP G +G LC
Sbjct: 2397 LCPYGRSGPLC 2407
Score = 45.1 bits (105), Expect = 0.001
Identities = 23/90 (25%), Positives = 34/90 (37%), Gaps = 10/90 (11%)
Query: 447 PRCEIDVNECVSNPCQ-----NDATCLDQIGEFQCICMPGYEGVHCEVNTDEC-----AS 496
P V +C ++PC N TC++ C C G++G C C
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 497 SPCLHNGRCLDKINEFQCECPTGFTGHLCQ 526
C C+ + + C CP G TG C+
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 6/90 (6%)
Query: 364 GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANP- 422
GR+ CH + C C G C + + C C +G+ G C++ V C +P
Sbjct: 2603 GRSVGQCHASP-CSLMKCGNGGTCIESGTS--VYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 423 --CEHAGKCINTLGSFECQCLQGYTGPRCE 450
C CI+ + C C G TG CE
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 45.1 bits (105), Expect = 0.001
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 43 TEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPL 102
TE GG+ VG C D C C+N G C V ++C C ++G C +
Sbjct: 2861 TEFGAKGGSNVGD-C-DGTACGYNTCRNGGECTV----NGTTFSCRCLPDWAGNTCNQSV 2914
Query: 103 DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ 139
+CL N C + C Y C C GW G+ C+
Sbjct: 2915 --SCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 45.1 bits (105), Expect = 0.001
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Query: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC-TDYLGGYSCKCVAG 1174
C++GG C G T CRC + G+ C V C + C + + C D YSC C G
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
Query: 1175 YHGVNCSEE 1183
+ G C +
Sbjct: 2943 WVGRYCENK 2951
Score = 44.7 bits (104), Expect = 0.001
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Query: 30 TCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
TC NGG+C T +C C + G C CL+ C + C + D+ Y+C C
Sbjct: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLC-IPDQS--FSYSCLC 2939
Query: 90 ALGFSGPLC 98
LG+ G C
Sbjct: 2940 TLGWVGRYC 2948
Score = 44.3 bits (103), Expect = 0.002
Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 144 CASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGS-Y 202
CA + C N G C+ + C CP + G C+ C P C +G TC + G+
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNP--CGNGATCVPKSGTDI 2394
Query: 203 RCVCRATHTGPNC 215
C+C +GP C
Sbjct: 2395 VCLCPYGRSGPLC 2407
Score = 43.9 bits (102), Expect = 0.002
Identities = 30/86 (34%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNAC-----LTNPCRNGG 115
+PC C N GTC G + Y C+C G+ G C T + C + C G
Sbjct: 2612 SPCSLMKCGNGGTCI---ESGTSVY-CNCTTGWKGSFC-TETVSTCDPEHDPPHHCSRGA 2666
Query: 116 TCDLLTLTEYKCRCPPGWSGKSCQQA 141
TC L Y C CP G +G C+QA
Sbjct: 2667 TCISLP-HGYTCFCPLGTTGIYCEQA 2691
Score = 43.9 bits (102), Expect = 0.002
Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 1237 KCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNEC---LSNPCDARGTQNCVQRVNDFHC 1293
KC N GTC++ C C G+ G C V+ C P C+ + + C
Sbjct: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
Query: 1294 ECRAGHTGRRCESVIN 1309
C G TG CE ++
Sbjct: 2678 FCPLGTTGIYCEQALS 2693
Score = 43.9 bits (102), Expect = 0.002
Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Query: 178 DVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTG 237
D CG CR+GG C ++ C C G C + V C + C + C P
Sbjct: 2875 DGTACGYNT--CRNGGECTVNGTTFSCRCLPDWAGNTCNQS-VSCLNNLCLHQSLCIPDQ 2931
Query: 238 DVTHECACLPGFTGQNCE 255
++ C C G+ G+ CE
Sbjct: 2932 SFSYSCLCTLGWVGRYCE 2949
Score = 42.0 bits (97), Expect = 0.008
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 987 CTESSCFNGGTC-----VDGINSFTCLCPPGFTGSYCQHD 1021
C + C NGGTC GI SF C CP FTG +C+ D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 42.0 bits (97), Expect = 0.008
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 6/79 (7%)
Query: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG-TCLDKI-DGYEC 664
C+ CR+ GTC + C C + +G C+ C ++PC +G TC+ K C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
Query: 665 ACEPGYTGSMCN--INIDE 681
C G +G +C INI +
Sbjct: 2397 LCPYGRSGPLCTDAINITQ 2415
Score = 42.0 bits (97), Expect = 0.008
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 7/87 (8%)
Query: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARG 1280
NV DC+ + C N G C +SC C P + G C V+ CL+N C +
Sbjct: 2870 NVGDCDGTACGYNT---CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQS 2925
Query: 1281 TQNCV-QRVNDFHCECRAGHTGRRCES 1306
C+ + + C C G GR CE+
Sbjct: 2926 L--CIPDQSFSYSCLCTLGWVGRYCEN 2950
Score = 41.6 bits (96), Expect = 0.010
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 3/71 (4%)
Query: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCL-DKIDGYEC 664
C CR+GG C + C CL G C ++ C ++ C C+ D+ Y C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 665 ACEPGYTGSMC 675
C G+ G C
Sbjct: 2938 LCTLGWVGRYC 2948
Score = 41.2 bits (95), Expect = 0.013
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 1349 ARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNP---CYNQGTCEP 1405
A C ++C NGGTCI S C C + G C S+ +P C TC
Sbjct: 2611 ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC-- 2668
Query: 1406 TSESPFYRCLCPAKFNGLLC 1425
S Y C CP G+ C
Sbjct: 2669 ISLPHGYTCFCPLGTTGIYC 2688
Score = 41.2 bits (95), Expect = 0.013
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 8/79 (10%)
Query: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS------NPCNEGSNCDTNPV 392
C+ C +G TC + S YC C G G C + + C+ G+ C + P
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 393 NGKAICTCPSGYTGPACSQ 411
C CP G TG C Q
Sbjct: 2674 G--YTCFCPLGTTGIYCEQ 2690
Score = 40.8 bits (94), Expect = 0.017
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 53 VGPRCQDPNPCLSTPCKNAGTCHVVD-RRGVADYACSCALGFSGPLC 98
V P P+ C C N GTCH + G+ + C C L F+G C
Sbjct: 2093 VSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
Score = 40.8 bits (94), Expect = 0.017
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 5/40 (12%)
Query: 911 CRPNPCHNGGSC-----TDGINTAFCDCLPGFRGTFCEED 945
C+ + CHNGG+C + GI + CDC F G FCE+D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 38.9 bits (89), Expect = 0.066
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
Query: 641 NLDDCASSPCDSGTCLD----KIDG--YECACEPGYTGSMCNINIDECAGNPCHNGGTC- 693
N+ DC + C TC + ++G + C C P + G+ CN ++ C N C + C
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCI 2928
Query: 694 EDGINGFTCRCPEGYHDPTC 713
D ++C C G+ C
Sbjct: 2929 PDQSFSYSCLCTLGWVGRYC 2948
Score = 38.1 bits (87), Expect = 0.11
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 6/86 (6%)
Query: 329 GEDCSENIDDCASAACFH-----GATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNE 383
G N+ DC AC + G C +F C C G C+ + +C++N C
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLH 2923
Query: 384 GSNCDTNPVNGKAICTCPSGYTGPAC 409
S C + + C C G+ G C
Sbjct: 2924 QSLCIPDQ-SFSYSCLCTLGWVGRYC 2948
Score = 37.7 bits (86), Expect = 0.15
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 209 THTGPNCERPYVPCSPSPCQNGGTCRP----TGDVTHECACLPGFTGQNCEEN 257
T P+ P V C C NGGTC +G V+ +C C FTG+ CE++
Sbjct: 2091 TSVSPSVAAPSV-CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 37.0 bits (84), Expect = 0.25
Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
Query: 1311 CKGKPCKNGGTCAVA--SNTARGFICKCPAGFEGATCENDA 1349
C+ C NGGTC S+ F C CP F G CE DA
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDA 2143
Score = 36.2 bits (82), Expect = 0.43
Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 261 CPGNNCKNGGAC-----VDGVNTYNCRCPPEWTGQYCTED 295
C + C NGG C G+ ++ C CP +TG++C +D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 35.4 bits (80), Expect = 0.73
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 12/58 (20%)
Query: 1005 FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQ-----DGCGSYRCTCPQGYTGPNCQ 1057
+T + P S CQ DV C +GGTC G S++C CP +TG C+
Sbjct: 2090 WTSVSPSVAAPSVCQQDV-------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
Score = 35.0 bits (79), Expect = 0.95
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 104 NACLTNPCRNGGTCDLLTLT----EYKCRCPPGWSGKSCQQADPCASNPCANGGQCL 156
+ C + C NGGTC + L+ ++C CP ++G+ C++ D P NG L
Sbjct: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK-DAGLFFPSFNGNSYL 2156
Score = 34.7 bits (78), Expect = 1.2
Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 5/46 (10%)
Query: 829 VLAP--CAPSPCRNGGECRQ---SEDYESFSCVCPTGWQGQTCEVD 869
V AP C C NGG C S SF C CP + G+ CE D
Sbjct: 2097 VAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 34.3 bits (77), Expect = 1.6
Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 11/66 (16%)
Query: 923 TDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC-----TDCVDSYTCTCPAGFSG 977
T G++T + P + C D C NG C + + S+ C CP F+G
Sbjct: 2083 TQGVDTMWTSVSPSVAAP------SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTG 2136
Query: 978 IHCENN 983
CE +
Sbjct: 2137 RFCEKD 2142
Score = 34.3 bits (77), Expect = 1.6
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 6/53 (11%)
Query: 339 CASAACFHGATCH-----DRVASFYCECPHGRTGLLCHLNDACISNPCNEGSN 386
C C +G TCH + SF C+CP TG C DA + P G++
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE-KDAGLFFPSFNGNS 2154
Score = 34.3 bits (77), Expect = 1.6
Identities = 21/90 (23%), Positives = 32/90 (35%), Gaps = 6/90 (6%)
Query: 1261 GERCEGDVNECLSNPCDARGTQN---CVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
G + +V +C C +N C F C C G C ++ C C
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCL 2922
Query: 1318 NGGTCAVASNTARGFICKCPAGFEGATCEN 1347
+ C + + + C C G+ G CEN
Sbjct: 2923 HQSLCI--PDQSFSYSCLCTLGWVGRYCEN 2950
Score = 33.9 bits (76), Expect = 2.1
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 7/59 (11%)
Query: 494 CASSPCLHNGRC-----LDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 547
C C + G C I FQC+CP FTG C+ D P NG L+ P
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAG--LFFPSFNGNSYLELP 2159
Score = 33.5 bits (75), Expect = 2.8
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 15/56 (26%)
Query: 168 PSFHGPT-CRQDVNECGQKPGLCRHGGTCH-----NEVGSYRCVCRATHTGPNCER 217
PS P+ C+QDV C +GGTCH + + S++C C TG CE+
Sbjct: 2095 PSVAAPSVCQQDV---------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
Score = 32.7 bits (73), Expect = 4.7
Identities = 14/29 (48%), Positives = 15/29 (51%), Gaps = 5/29 (17%)
Query: 682 CAGNPCHNGGTC-----EDGINGFTCRCP 705
C + CHNGGTC GI F C CP
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCP 2131
Score = 32.0 bits (71), Expect = 8.0
Identities = 12/38 (31%), Positives = 18/38 (47%), Gaps = 5/38 (13%)
Query: 1063 CDSSPCKNGGKCWQTH-----TQYRCECPSGWTGLYCD 1095
C C NGG C ++C+CP +TG +C+
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 518 bits (1335), Expect = e-146
Identities = 266/801 (33%), Positives = 390/801 (48%), Gaps = 99/801 (12%)
Query: 579 SCKDGVATFTC--LCRP--GYTGHH-CETNIN----------ECSSQPCRHG-----GTC 618
+C D F C CRP + GH+ C+ N N EC+ CR G G+C
Sbjct: 186 TCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSC 245
Query: 619 QDRDNAYLCFCLKGTTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGYTGSMCNI 677
+ + C C G G C D C P C G C + ++C CE + G +C+
Sbjct: 246 KLPGD---CRCQYGWQGLYC----DKCIPHPGCVHGICNEP---WQCLCETNWGGQLCDK 295
Query: 678 NIDECAGN-PCHNGGTCED-GINGFTCRCPEGYHDPTCLSEVNECNSNPCVH-GACRDSL 734
+++ C + PC NGGTC + G + + C CPEGY P C + C S+PC + G+C+++
Sbjct: 296 DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETS 355
Query: 735 NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE 794
G++C+C PGW+G C N ++C N C +GGTC+D+ +G+ C C ++G CQ + NE
Sbjct: 356 LGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANE 415
Query: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFS 854
C + PC+N +C + +A Y C+CL + G C++ + C C+N CR + +
Sbjct: 416 CEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL-GQCQNDASCRDLVN--GYR 472
Query: 855 CVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPN 914
C+CP G+ G CE DI+EC +PC +G CQN ++C C G+SG C+ DID C PN
Sbjct: 473 CICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN 532
Query: 915 PCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDS-------- 966
PC NG C + + FC C + G C + C + PC +CT + S
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVR 592
Query: 967 --------------------YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFT 1006
+TC C GF+G +C N DC + C NGGTC+DG+NS+
Sbjct: 593 YISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYK 652
Query: 1007 CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSS 1066
C+C G+ G+YC+ ++N+C PC +GGTC+D + C C G+ G C + CD +
Sbjct: 653 CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA 712
Query: 1067 PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG 1126
C NGG C+ ++C CP GW G C++ R + C +GG CV G
Sbjct: 713 TCNNGGTCYDEGDAFKCMCPGGWEGTTCNI---------ARNSSCLPNPCHNGGTCVVNG 763
Query: 1127 NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDE 1186
+ C C+ G+ G C ++CSP PC N TC D Y C+C G+ G +C I+E
Sbjct: 764 ESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININE 823
Query: 1187 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVD 1246
C S PC G TC+D N Y+C CP G G C+ VS P C G+ +
Sbjct: 824 CQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ-----------EVSGRP-CITMGSVIP 871
Query: 1247 QVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCES 1306
+ C +C C C G + C+ ++ H EC +G + C
Sbjct: 872 DGAKWDDDCNTC----QCLNGRIACSKVWC---GPRPCL--LHKGHSECPSGQS---CIP 919
Query: 1307 VING-CKGKPCKNGGTCAVAS 1326
+++ C PC G C +S
Sbjct: 920 ILDDQCFVHPCTGVGECRSSS 940
Score = 510 bits (1314), Expect = e-144
Identities = 286/844 (33%), Positives = 397/844 (47%), Gaps = 132/844 (15%)
Query: 85 YAC------SCALGFSGPLCLTPLDNACLTNPCRNG-----GTCDLLTLTEYKCRCPPGW 133
YAC +C G+ GP C + CR G G+C L CRC GW
Sbjct: 210 YACDQNGNKTCMEGWMGPECNRAI--------CRQGCSPKHGSCKL----PGDCRCQYGW 257
Query: 134 SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGG 193
G C D C +P G C + C C ++ G C +D+N CG C +GG
Sbjct: 258 QGLYC---DKCIPHPGCVHGIC---NEPWQCLCETNWGGQLCDKDLNYCGTHQP-CLNGG 310
Query: 194 TCHNE-VGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQ 252
TC N Y+C C ++GPNCE C PC N G+C+ T + EC C PG+TG
Sbjct: 311 TCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETS-LGFECECSPGWTGP 369
Query: 253 NCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMP--------- 303
C NIDDC NNC +GG C D VN + C CPP+WTG+ C D +EC+ P
Sbjct: 370 TCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKN 429
Query: 304 --------------------------NACQNGGTCHNTHGGYNCVCVNGWTGEDCSENID 337
CQN +C + GY C+C G+ G+ C +ID
Sbjct: 430 LIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDID 489
Query: 338 DCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKA 396
+CAS C +G C + + F C CP G +G LC L+ D C NPC G+ C
Sbjct: 490 ECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRA--SDY 547
Query: 397 ICTCPSGYTGPACSQDVDECS-------------------------LGANPCEHAGKCIN 431
C CP Y G CS D C + +N C GKC +
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 432 TLG-SFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN 490
G F C C +G+TG C ++N+C SNPC+N TC+D + ++CIC G+EG +CE N
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667
Query: 491 TDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTY 550
++C+ +PC + G C D +N+F C+C G+ G C +C C NG C D + +
Sbjct: 668 INDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAF 727
Query: 551 TCVCTEGYTGTHCEVDID-ECDPDPCHY-GSCKDGVATFTCLCRPGYTGHHCETNINECS 608
C+C G+ GT C + + C P+PCH G+C +FTC+C+ G+ G C N N+CS
Sbjct: 728 KCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCS 787
Query: 609 SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG-TCLDKIDGYECACE 667
PC + GTC D DN Y C C G GP+C IN+++C SSPC G TC+D+I+GY C C
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 668 PGYTGSMCNINIDECAGNPC-------HNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC 720
PG++G+ C E +G PC +G +D N TC+C G S+V C
Sbjct: 848 PGHSGAKC----QEVSGRPCITMGSVIPDGAKWDDDCN--TCQCLNG---RIACSKV-WC 897
Query: 721 NSNPCVHGACRDSLNGYKCDCDPGWSGTNC-DINNNECESNPCVNGGTCKDMTSGYVCT- 778
PC+ L+ +C SG +C I +++C +PC G C+ + V T
Sbjct: 898 GPRPCL-------LHKGHSECP---SGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTK 947
Query: 779 -CREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNC-LLPYTGATCEVVLAPCAPS 836
+ + NC NI + ++ G + + N +L A + +A C PS
Sbjct: 948 CTSDSYYQDNC-ANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIA-CEPS 1005
Query: 837 PCRN 840
P N
Sbjct: 1006 PSAN 1009
Score = 509 bits (1311), Expect = e-143
Identities = 260/773 (33%), Positives = 373/773 (48%), Gaps = 71/773 (9%)
Query: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
N C+ GW G +C+ I C +C C C +G GL C D CI +
Sbjct: 217 NKTCMEGWMGPECNRAI--CRQGCSPKHGSCK---LPGDCRCQYGWQGLYC---DKCIPH 268
Query: 380 PCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINT-LGSFEC 438
P C N C C + + G C +D++ C PC + G C NT ++C
Sbjct: 269 P-----GCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTH-QPCLNGGTCSNTGPDKYQC 322
Query: 439 QCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSP 498
C +GY+GP CEI + C+S+PC N +C + F+C C PG+ G C N D+C+ +
Sbjct: 323 SCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 499 CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGY 558
C H G C D +N F+C CP +TG CQ D +EC + PC N C + +Y C C G+
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Query: 559 TGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTC 618
G +C+++I++C + SC+D V + C+C PGY G HCE +I+EC+S PC +GG C
Sbjct: 443 MGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHC 502
Query: 619 QDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT-CLDKIDGYECACEPGYTGSMCNI 677
Q+ N + C C G +G C++++D C +PC +G C ++ Y C C Y G C+
Sbjct: 503 QNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSH 562
Query: 678 NIDECAGNPCH---------------------------NGGTCEDGING-FTCRCPEGYH 709
D C PC G C+ G FTC C +G+
Sbjct: 563 LKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Query: 710 DPTCLSEVNECNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTC 768
C +N+C SNPC + G C D +N YKC C GW G C+ N N+C NPC NGGTC
Sbjct: 623 GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC 682
Query: 769 KDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEV 828
+D+ + + C C+ G+ G C + ++C C N GTC D+ +KC C + G TC +
Sbjct: 683 RDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNI 742
Query: 829 VL-APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNT 887
+ C P+PC NGG C + ESF+CVC GW+G C + N+C PC + +C +
Sbjct: 743 ARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDG 800
Query: 888 HGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDIN 947
YRC C G++G +C +I++C+ +PC G +C D IN C C PG G C+
Sbjct: 801 DNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---- 856
Query: 948 ECASDPC-------RNGANCTDCVDSYTCTCPAG---FSGIHCENNTPDCT----ESSCF 993
E + PC +GA D D TC C G S + C C S C
Sbjct: 857 EVSGRPCITMGSVIPDGAKWDD--DCNTCQCLNGRIACSKVWC--GPRPCLLHKGHSECP 912
Query: 994 NGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCT 1046
+G +C+ ++ C P C+ + C QD C + T
Sbjct: 913 SGQSCIPILDD-QCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFT 964
Score = 478 bits (1230), Expect = e-134
Identities = 246/721 (34%), Positives = 340/721 (47%), Gaps = 62/721 (8%)
Query: 692 TCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCD 751
TC+D GF C C G NG K C GW G C
Sbjct: 186 TCDDYYYGFGCN--------------KFCRPRDDFFGHYACDQNGNKT-CMEGWMGPEC- 229
Query: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVA 811
N C G+CK C C+ G+ G C ++C +P G C +
Sbjct: 230 -NRAICRQGCSPKHGSCKLPGD---CRCQYGWQGLYC----DKCIPHPGCVHGICNEP-- 279
Query: 812 GYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDI 870
++C C + G C+ L C PC NGG C + + + C CP G+ G CE+
Sbjct: 280 -WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP-DKYQCSCPEGYSGPNCEIAE 337
Query: 871 NECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 930
+ C+ PC + SC+ T G+ C C G++G C T+IDDC PN C +GG+C D +N
Sbjct: 338 HACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397
Query: 931 CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTES 990
C C P + G C+ D NEC + PC N +C + + SY C C G+ G +C+ N DC
Sbjct: 398 CVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL-G 456
Query: 991 SCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQG 1050
C N +C D +N + C+CPPG+ G +C+ D++EC S PCL+GG CQ+ ++C CP G
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 1051 YTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD--------VPSV--- 1099
++G CQ + +C+ +PC+NG +C+ + Y C+CP + G C P
Sbjct: 517 FSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVID 576
Query: 1100 SCEVAAQR----QGVDV--ARLCQHGGLCVD-AGNTHHCRCQAGYTGSYCEDLVDECSPS 1152
SC VA +GV + +C G C +G C C G+TG+YC + +++C +
Sbjct: 577 SCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESN 636
Query: 1153 PCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG 1212
PC+NG TC D + Y C C G+ G C I++C +PC NGGTC DL N + C C G
Sbjct: 637 PCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNG 696
Query: 1213 TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNE-C 1271
+G C C+ C N GTC D+ + C CP G+ G C N C
Sbjct: 697 WKGKTCHSRDSQCDEAT--------CNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC 748
Query: 1272 LSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARG 1331
L NPC GT CV F C C+ G G C N C PC N GTC N R
Sbjct: 749 LPNPCHNGGT--CVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYR- 805
Query: 1332 FICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPC 1391
C+C GF G C + C S C G TC+ C+C +G +CQ + PC
Sbjct: 806 --CECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPC 863
Query: 1392 L 1392
+
Sbjct: 864 I 864
Score = 434 bits (1115), Expect = e-121
Identities = 238/729 (32%), Positives = 336/729 (46%), Gaps = 79/729 (10%)
Query: 27 PGETCLNGGKCEAANGTEACVCGGAFVGPRC-QDPNPC-LSTPCKNAGTCHVVDRRGVAD 84
P C++G N C+C + G C +D N C PC N GTC G
Sbjct: 267 PHPGCVHG----ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTC---SNTGPDK 319
Query: 85 YACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADP 143
Y CSC G+SGP C ++ACL++PC N G+C +L ++C C PGW+G +C D
Sbjct: 320 YQCSCPEGYSGPNC-EIAEHACLSDPCHNRGSCKETSL-GFECECSPGWTGPTCSTNIDD 377
Query: 144 CASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYR 203
C+ N C++GG C + C CPP + G TC+ D NEC KP C + +C N + SY
Sbjct: 378 CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP--CVNAKSCKNLIASYY 435
Query: 204 CVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPG 263
C C G NC+ C CQN +CR + + C C PG+ G +CE +ID+C
Sbjct: 436 CDCLPGWMGQNCDININDCL-GQCQNDASCRDLVN-GYRCICPPGYAGDHCERDIDECAS 493
Query: 264 NNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC 323
N C NGG C + +N + C CP ++G C D+D C+ PN CQNG C+N Y C C
Sbjct: 494 NPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCE--PNPCQNGAQCYNRASDYFCKC 551
Query: 324 VNGWTGEDCSENIDDCASAACF----------------------------HGATCHDRVA 355
+ G++CS D C + C HG
Sbjct: 552 PEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG 611
Query: 356 SFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD 414
F C+C G TG CH N + C SNPC G C + K C C G+ G C +++
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYK--CICSDGWEGAYCETNIN 669
Query: 415 ECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEF 474
+CS NPC + G C + + F C C G+ G C ++C C N TC D+ F
Sbjct: 670 DCS--QNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAF 727
Query: 475 QCICMPGYEGVHCEV-NTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECA 533
+C+C G+EG C + C +PC + G C+ F C C G+ G +C + ++C+
Sbjct: 728 KCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCS 787
Query: 534 STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG-SCKDGVATFTCLCR 592
PC N C+DG N Y C C G+ G C ++I+EC PC +G +C D + + C+C
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 593 PGYTGHHCETNINECSSQPCRHGGT-----CQDRDNAYLCFCLKGTTGPNCEINLDDCAS 647
PG++G C+ E S +PC G+ + D+ C CL G C+
Sbjct: 848 PGHSGAKCQ----EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIA---------CSK 894
Query: 648 SPCDSGTCLDKIDGYECACEPGYTGSMC-NINIDECAGNPCHNGGTC-EDGINGFTCRC- 704
C CL EC +G C I D+C +PC G C + +C
Sbjct: 895 VWCGPRPCLLHKGHSECP-----SGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCT 949
Query: 705 PEGYHDPTC 713
+ Y+ C
Sbjct: 950 SDSYYQDNC 958
Score = 410 bits (1053), Expect = e-113
Identities = 240/735 (32%), Positives = 333/735 (45%), Gaps = 141/735 (19%)
Query: 767 TCKDMTSGYVCT--CR---EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY 821
TC D G+ C CR + F C N N+ TC++ G +CN +
Sbjct: 186 TCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNK----------TCMEGWMGPECNRAICR 235
Query: 822 TGATCEVVLAPCAPS--PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP-C 878
G C+P C+ G+CR C GWQG C+ +C+ P C
Sbjct: 236 QG---------CSPKHGSCKLPGDCR-----------CQYGWQGLYCD----KCIPHPGC 271
Query: 879 RHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPN-PCHNGGSCTD-GINTAFCDCLPG 936
HG C ++C C+ + G+ C+ D++ C + PC NGG+C++ G + C C G
Sbjct: 272 VHGI-CNEP---WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEG 327
Query: 937 FRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 996
+ G CE + C SDPC N +C + + C C G++G C N DC+ ++C +GG
Sbjct: 328 YSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387
Query: 997 TCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 1056
TC D +N F C+CPP +TG CQ D NEC+++PC++ +C++ SY C C G+ G NC
Sbjct: 388 TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447
Query: 1057 QNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLC 1116
++ C C+N C YRC CP G+ G +C+ C + C
Sbjct: 448 DININDC-LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDEC----------ASNPC 496
Query: 1117 QHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH 1176
+GG C + N C C G++G+ C+ +D C P+PCQNGA C + Y CKC Y
Sbjct: 497 LNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Query: 1177 GVNCSEEIDECLSHPCQNGGTCL------DLPN----------------------TYKCS 1208
G NCS D C + PC+ +C D P + C
Sbjct: 557 GKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCD 616
Query: 1209 CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDV 1268
C +G G +C N++DC S C N GTC+D V Y C C G+ G CE ++
Sbjct: 617 CNKGFTGTYCHENINDCE--------SNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI 668
Query: 1269 NECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNT 1328
N+C NPC GT C VNDF+C+C+ G G+ C S + C C NGGTC +
Sbjct: 669 NDCSQNPCHNGGT--CRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCY---DE 723
Query: 1329 ARGFICKCPAGFEGATCENDARTCGSLR--CLNGGTCISGPRSPTCLCLGPFTGPECQFP 1386
F C CP G+EG TC N AR L C NGGTC+ S TC+C + GP C
Sbjct: 724 GDAFKCMCPGGWEGTTC-NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA-Q 781
Query: 1387 ASSPCLGGNPCYNQGTC------------------------EPTSESPF----------- 1411
++ C +PCYN GTC SP
Sbjct: 782 NTNDC-SPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEIN 840
Query: 1412 -YRCLCPAKFNGLLC 1425
YRC+CP +G C
Sbjct: 841 GYRCVCPPGHSGAKC 855
Score = 346 bits (887), Expect = 2e-94
Identities = 224/725 (30%), Positives = 302/725 (41%), Gaps = 134/725 (18%)
Query: 892 RCHCQAGYSGRNCETDIDDCRPNPCHNGG-SCTDGINTAFCDCLPGFRGTFCEEDINECA 950
R C Y G C CRP G +C N C+ G+ G C I
Sbjct: 184 RVTCDDYYYGFGCNKF---CRPRDDFFGHYACDQNGNKT---CMEGWMGPECNRAI---- 233
Query: 951 SDPCRNGANCT--DCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGI--NSFT 1006
CR G + C C C G+ G++C+ C CV GI +
Sbjct: 234 ---CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDK---------CIPHPGCVHGICNEPWQ 281
Query: 1007 CLCPPGFTGSYCQHDVNECDS-QPCLHGGTCQD-GCGSYRCTCPQGYTGPNCQNLVHWCD 1064
CLC + G C D+N C + QPCL+GGTC + G Y+C+CP+GY+GPNC+ H C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACL 341
Query: 1065 SSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD 1124
S PC N G C +T + CEC GWTG C C C HGG C D
Sbjct: 342 SDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCS----------PNNCSHGGTCQD 391
Query: 1125 AGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
N C C +TG C+ +EC PC N +C + + Y C C+ G+ G NC I
Sbjct: 392 LVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDINI 451
Query: 1185 DECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC 1244
++CL CQN +C DL N Y+C CP G G HCE ++D+C S C N G C
Sbjct: 452 NDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDEC--------ASNPCLNGGHC 502
Query: 1245 VDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRC 1304
+++ + C CP GF G C+ D++ C NPC G Q C R +D+ C+C + G+ C
Sbjct: 503 QNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQ-NGAQ-CYNRASDYFCKCPEDYEGKNC 560
Query: 1305 ESVINGCKGKPCKNGGTCAVA-------------------------SNTARGFICKCPAG 1339
+ + C+ PC+ +C VA S + F C C G
Sbjct: 561 SHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKG 620
Query: 1340 FEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYN 1399
F G C + C S C NGGTCI G S C+C + G C+ + NPC+N
Sbjct: 621 FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND--CSQNPCHN 678
Query: 1400 QGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 1459
GTC + FY C C + G CH D +C E
Sbjct: 679 GGTCRDL-VNDFY-CDCKNGWKGKTCHSRD----------------------SQCDE--- 711
Query: 1460 NKVCSLQCNNHACGWDGGD-----CSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAG- 1513
CNN +D GD C + N ++ C + C++ G
Sbjct: 712 -----ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC--------LPNPCHNGGT 758
Query: 1514 CLFDG--FDCQRAEGQCNPLYDQY---CKDH--FSDGHCDQGCNSAECE----WDGLDCA 1562
C+ +G F C EG P+ Q C H ++ G C G N CE + G DC
Sbjct: 759 CVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCR 818
Query: 1563 EHVPE 1567
++ E
Sbjct: 819 ININE 823
Score = 110 bits (275), Expect = 2e-23
Identities = 73/241 (30%), Positives = 101/241 (41%), Gaps = 30/241 (12%)
Query: 19 ARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQ--DPNPCLSTPCKNAGTCHV 76
+R +C + TC NGG C C+C G + G C + CL PC N GTC V
Sbjct: 704 SRDSQCDEA--TCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVV 761
Query: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
+ C C G+ GP+C N C +PC N GTC + Y+C C PG++G
Sbjct: 762 ----NGESFTCVCKEGWEGPIC-AQNTNDCSPHPCYNSGTC-VDGDNWYRCECAPGFAGP 815
Query: 137 SCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQ-DVNECGQKPGLCRHGGT 194
C+ + C S+PCA G C+ Y C CPP G C++ C + G
Sbjct: 816 DCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAK 875
Query: 195 CHNEVGSYRCV-----CRATHTGPNCERPYVPC----SPSPCQNGGTCRPTGD---VTHE 242
++ + +C+ C GP PC S C +G +C P D H
Sbjct: 876 WDDDCNTCQCLNGRIACSKVWCGPR------PCLLHKGHSECPSGQSCIPILDDQCFVHP 929
Query: 243 C 243
C
Sbjct: 930 C 930
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 511 bits (1316), Expect = e-144
Identities = 465/1622 (28%), Positives = 655/1622 (40%), Gaps = 354/1622 (21%)
Query: 34 GGKCEAANGTEACVCG-GAFVGPR---CQDPNPCLSTP--CKNAGTCHVVDRRGVADYAC 87
GG C G+ C C G + P C D N C + C N +++ + Y C
Sbjct: 1126 GGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGK-----YQC 1180
Query: 88 SCALGFSGP---LCLTPLDNACLTNPCRNGGTCDLLTLTE--YKCRCPPGWS----GKSC 138
+C G+ L +D + N GG T +E Y+C C PG++ +SC
Sbjct: 1181 ACNPGYHSTPDRLFCVDIDECSIMN----GGCETFCTNSEGSYECSCQPGFALMPDQRSC 1236
Query: 139 QQADPCASNP-CANGGQCLPFEASYICHCPPSFHGP----TCRQDVNECGQKPGLCRHGG 193
D C NP +GGQC Y C C F TC DVNEC P +C G
Sbjct: 1237 TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTC-VDVNECDLNPNICL-SG 1294
Query: 194 TCHNEVGSYRCVCRATHTGP-----------------NCERPYV--------PCSPSP-- 226
TC N GS+ C C ++G NC + V CS SP
Sbjct: 1295 TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354
Query: 227 ------------CQNGG-TCRPTGDV-----THECACLPGFTGQNCE-ENIDDCPGN-NC 266
C NG C D ++ C C G+TG ++D+C N N
Sbjct: 1355 IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNL 1414
Query: 267 KNGGACVDGVNTYNCRCP----PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCV 322
G C++ Y C C P G+ C ED+DEC L PN C G TCHN G + C
Sbjct: 1415 CGNGQCLNAPGGYRCECDMGFVPSADGKAC-EDIDECSL-PNICVFG-TCHNLPGLFRCE 1471
Query: 323 CVNGW----TGEDCSENIDDCASAACFHGATCHDRVASFYCECPHG------RTGLLCHL 372
C G+ +G +C++ +++C C + S+ C+CP R G +
Sbjct: 1472 CEIGYELDRSGGNCTD-VNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTR 1530
Query: 373 NDACISNPCNEGSNCDTNPVN------GKAICTCPSGYT-GPACS--------------- 410
+ C + G N DT N KA C C G G C
Sbjct: 1531 SGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCP 1590
Query: 411 --------------QDVDECSLGANPCEHAGKCINTLGSFECQCLQGY---TGPRCEIDV 453
+D+DEC C+ GKCINT GSF+C+C GY R DV
Sbjct: 1591 GGEGFRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCRCPTGYYLNEDTRVCDDV 1649
Query: 454 NECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHN---------GR 504
NEC + TC + +G + CIC P Y V+ N + S C N G
Sbjct: 1650 NECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGE 1709
Query: 505 CLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKC-LDGPNTYTCVCTEGYTG--- 560
L + + C C Y++ + PC+ +C + + + +C G
Sbjct: 1710 LLFNMTKKMC---------CCSYNIGRAWNKPCE---QCPIPSTDEFATLCGSQRPGFVI 1757
Query: 561 ---THCEVDIDECD--PDPCHYGSCKDGVATFTCLCRPGYTGHH----CETNINECSSQP 611
T VDIDEC P C G C + V +F C C G+ + CE +I+EC + P
Sbjct: 1758 DIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGP 1816
Query: 612 -CRHGGTCQDRDNAYLCFCLKG---TTGPNCEINLDDCASSP--CDSGTCLDKIDGYECA 665
C+ C + +Y C C G T+ C + ++C P C G C+D + + C
Sbjct: 1817 VCQRNAECINTAGSYRCDCKPGYRFTSTGQCN-DRNECQEIPNICSHGQCIDTVGSFYCL 1875
Query: 666 CEPGYTGS----MCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGY---HDPTCLSEVN 718
C G+ + MC ++I+EC + C NG TC + I F CRC G+ H+ C+ +V+
Sbjct: 1876 CHTGFKTNDDQTMC-LDINECERDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCI-DVD 1932
Query: 719 EC---NSNPCVHGACRDSLNGYKCDCDPGWS----GTNC-DINNNECESNPCVNGGTCKD 770
EC N N C +G C +++ ++C C+ G+ G C DIN E C G TC++
Sbjct: 1933 ECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPG-TCQN 1991
Query: 771 MTSGYVCTCREGFSGPN--CQTNINECASNPCLNQ-GTCIDDVAGYKCNC----LLPYTG 823
+ Y C C G+S N C+ +I+EC P + GTC + +KC C L +G
Sbjct: 1992 LDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 2050
Query: 824 ATCEVV-LAPCAPSPCRNGGECR--QSEDYESFSCVCPT---GWQGQTCE---------- 867
C+ + ++ C GG+C +S ++ C C GW G CE
Sbjct: 2051 RRCQDLRMSYCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGW-GDPCELCPTEPDEAF 2107
Query: 868 ------------------VDINECVLSP-CRHGASCQNTHGGYRCHCQAGY--SGRNCET 906
VD++EC C+HG C NT G YRC C GY +G C
Sbjct: 2108 RQICPYGSGIIVGPDDSAVDMDECKEPDVCKHG-QCINTDGSYRCECPFGYILAGNEC-V 2165
Query: 907 DIDDCRP-NPCHNGGSCTDGINTAFCDCLPGFRG--TFCEEDINECASDPCRNGANCTDC 963
D D+C NPC NG +C + I C C GF EDINECA +P C +
Sbjct: 2166 DTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNT 2224
Query: 964 VDSYTCTCPAGF----------SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF 1013
SY C CP G+ CE DCTE C + I ++ C+C PG+
Sbjct: 2225 YGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQM----ECKNLIGTYMCICGPGY 2280
Query: 1014 T----GSYCQHDVNECDSQPCL-HGGTCQDGCGSYRCTCPQGYTG-PN----CQNLVHWC 1063
G C D NEC ++P + G C + GSY C C G+T PN N +C
Sbjct: 2281 QRRPDGEGCV-DENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYC 2339
Query: 1064 DS----SPCKNGGKCWQTHTQYRCECPSG--WTGLYCDVPSVSCEVAAQRQGVDVARLCQ 1117
+ + C+ G T+ C C G W CE+ + V +LC
Sbjct: 2340 FTEVLQNMCQIGSSNRNPVTKSECCCDGGRGW--------GPHCEICPFQGTVAFKKLCP 2391
Query: 1118 HG----------------------GLCVDAGNTHHCRCQAGYT----GSYCEDLVDECSP 1151
HG G CV+ ++HC C+ GYT G+ C DL +EC+
Sbjct: 2392 HGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDL-NECNQ 2450
Query: 1152 SPCQNGATCTDYLGGYSCKCVAGY----HGVNCSEEIDECLS--HPCQNGGTCLDLPNTY 1205
+P C + G Y C C GY G +C +++DEC + H CQ C++ +
Sbjct: 2451 APKPCNFICKNTEGSYQCSCPKGYILQEDGRSC-KDLDECATKQHNCQF--LCVNTIGGF 2507
Query: 1206 KCSCPRGTQGVHCE-INVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF----V 1260
C CP G H I+ ++C ++ C + G C + G ++C C GF
Sbjct: 2508 TCKCPPGFTQHHTSCIDNNECTSDIN------LCGSKGICQNTPGSFTCECQRGFSLDQT 2561
Query: 1261 GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGR----RCESVINGCKGKPC 1316
G CE DV+EC N G QN + + C C G+ +C N C
Sbjct: 2562 GSSCE-DVDECEGNHRCQHGCQNII---GGYRCSCPQGYLQHYQWNQCVDE-NECLSAHI 2616
Query: 1317 KNGGTCAVASNTARGFICKCPAGFE----GATCENDARTCGSLRCLNGGTCISGPRSPTC 1372
G +C NT + C CPAGF+ C+ D CGS + C + C
Sbjct: 2617 CGGASC---HNTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQAPCSYGCSNTEGGYLC 2672
Query: 1373 LC 1374
C
Sbjct: 2673 GC 2674
Score = 498 bits (1282), Expect = e-140
Identities = 429/1459 (29%), Positives = 612/1459 (41%), Gaps = 287/1459 (19%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPR----CQDPNPCLSTPCKNAGTCHVVDR 79
C CL+G CE G+ C C + G + C D N C N G H V
Sbjct: 1284 CDLNPNICLSG-TCENTKGSFICHCDMGYSGKKGKTGCTDINEC-EIGAHNCGK-HAVCT 1340
Query: 80 RGVADYACSCALGFSGP-LCLTPLDNACL-TNPCRNGGTCDLLTLTEYKCRCPPGWSGK- 136
+ CSC+ G+ G + T LD T+ C C T+ Y+C C G++G
Sbjct: 1341 NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKN-TMGSYRCLCKEGYTGDG 1399
Query: 137 -SCQQADPCASNP--CANGGQCLPFEASYICHCP----PSFHGPTCRQDVNECGQKPGLC 189
+C D C+ N C NG QCL Y C C PS G C +D++EC P +C
Sbjct: 1400 FTCTDLDECSENLNLCGNG-QCLNAPGGYRCECDMGFVPSADGKAC-EDIDECSL-PNIC 1456
Query: 190 RHGGTCHNEVGSYRCVCRATH----TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECAC 245
G TCHN G +RC C + +G NC P+ C +G G ++ C C
Sbjct: 1457 VFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPG--SYICDC 1513
Query: 246 LPGFTGQNCEENIDDCPGNNC--------KNGG-ACVD----GVNTYNC----------- 281
P F D NC NG AC + GV+ +C
Sbjct: 1514 PPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTP 1573
Query: 282 --RCPPEWTGQY-----------------CTEDVDECQLMPNACQNGGTCHNTHGGYNCV 322
CP T +Y ED+DECQ +P CQ GG C NT G + C
Sbjct: 1574 CEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCR 1632
Query: 323 CVNGW-TGEDCS--ENIDDCASAACFHGATCHDRVASFYCECP------HGRTGLLCHLN 373
C G+ ED +++++C + TC++ V ++ C CP +G +
Sbjct: 1633 CPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRR 1692
Query: 374 DACISNPCNEGSNCDTNPVNG--KAICTC-----------------PSG----------- 403
C N + CD + K +C C PS
Sbjct: 1693 SLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQR 1752
Query: 404 -------YTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPR----CEID 452
YTG D+DEC CE+ G CIN +GSF C+C G+ CE D
Sbjct: 1753 PGFVIDIYTG--LPVDIDECREIPGVCEN-GVCINMVGSFRCECPVGFFYNDKLLVCE-D 1808
Query: 453 VNECVSNP-CQNDATCLDQIGEFQCICMPGYEGVHCEVNTD--ECASSP--CLHNGRCLD 507
++EC + P CQ +A C++ G ++C C PGY D EC P C H G+C+D
Sbjct: 1809 IDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-GQCID 1867
Query: 508 KINEFQCECPTGFTGHLCQ---YDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
+ F C C TGF + Q D++EC C NG C + ++ C C G+ +H
Sbjct: 1868 TVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT-CRNTIGSFNCRCNHGFILSHNN 1926
Query: 565 --VDIDEC---DPDPCHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQPCRHG 615
+D+DEC + + C G C + V +F C C GY G C +INEC +P +
Sbjct: 1927 DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCA 1985
Query: 616 -GTCQDRDNAYLCFCLKGTTGPN--CEINLDDCASSP--CDSGTCLDKIDGYECACEPGY 670
GTCQ+ D +Y C C G + N CE ++D+C P C GTC + ++C C G+
Sbjct: 1986 PGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2044
Query: 671 TGSMCNINIDECAGNPCH---NGGTCED----GINGFTCRCP---EGYHDPTCLS----- 715
+ S + + C+ GG C + C C EG+ DP L
Sbjct: 2045 SLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPD 2104
Query: 716 ----------------------EVNECNS-NPCVHGACRDSLNGYKCDCDPGW--SGTNC 750
+++EC + C HG C ++ Y+C+C G+ +G C
Sbjct: 2105 EAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC 2164
Query: 751 DINNNECE-SNPCVNGGTCKDMTSGYVCTCREGFS-GP--NCQTNINECASNPCLNQGTC 806
++ +EC NPC NG TCK++ G+ CTC EGF GP C+ +INECA NP L C
Sbjct: 2165 -VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRC 2221
Query: 807 IDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSED------------YESFS 854
++ Y+C C + Y + C++ EC + + ++
Sbjct: 2222 VNTYGSYECKCPVGYVLREDRRM--------CKDEDECEEGKHDCTEKQMECKNLIGTYM 2273
Query: 855 CVCPTGWQ----GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSGRNCETDI 908
C+C G+Q G+ C VD NEC P C +G C NT G Y C C G++ +
Sbjct: 2274 CICGPGYQRRPDGEGC-VDENECQTKPGICENGR-CLNTRGSYTCECNDGFTA---SPNQ 2328
Query: 909 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRN-GANCTDCVDSY 967
D+C N G C + C R + +EC D R G +C C
Sbjct: 2329 DECLDN---REGYCFTEVLQNMCQIGSSNRNPVTK---SECCCDGGRGWGPHCEICPFQG 2382
Query: 968 TCT----CPAGFSGIHCENNTPDCT--ESSCFNGGTCVDGINSFTCLCPPGFT----GSY 1017
T CP G + + +C C NG CV+ S+ C+C G+T G+
Sbjct: 2383 TVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGTS 2441
Query: 1018 CQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT----GPNCQNLVHWCDSSPCKNGGK 1073
C D+NEC+ P C++ GSY+C+CP+GY G +C++L C +
Sbjct: 2442 CV-DLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDE-CATKQHNCQFL 2499
Query: 1074 CWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRC 1133
C T + C+CP G+T + SC + LC G+C + + C C
Sbjct: 2500 CVNTIGGFTCKCPPGFTQHH-----TSC--IDNNECTSDINLCGSKGICQNTPGSFTCEC 2552
Query: 1134 QAGY----TGSYCEDLVDECSPSP-CQNGATCTDYLGGYSCKCVAGY----HGVNCSEEI 1184
Q G+ TGS CED VDEC + CQ+G C + +GGY C C GY C +E
Sbjct: 2553 QRGFSLDQTGSSCED-VDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCVDE- 2608
Query: 1185 DECLSHPCQNGGTCLDLPNTYKCSCPRGTQ----GVHCEINVDDCNPPVDPVSRSPKCFN 1240
+ECLS G +C + +YKC CP G Q C+ ++++C P S
Sbjct: 2609 NECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQAPCSYG----- 2662
Query: 1241 NGTCVDQVGGYSCTCPPGF 1259
C + GGY C CPPG+
Sbjct: 2663 ---CSNTEGGYLCGCPPGY 2678
Score = 493 bits (1269), Expect = e-138
Identities = 483/1741 (27%), Positives = 696/1741 (39%), Gaps = 382/1741 (21%)
Query: 31 CLNGGKCEAANGTEACVCGGAF---VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYAC 87
C NG +C G+ C C F + C D + C PC G C ++ +G Y C
Sbjct: 460 CQNG-RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAG-GEC--INNQG--SYTC 513
Query: 88 SCALGFSGPLCLTPLDNA--CLTNP--CRNGGTCDLLTLTEYKCRCPPGW----SGKSCQ 139
C G+ L T + CL N C NG + T + C C G+ GK+C+
Sbjct: 514 QCRAGYQSTLTRTECRDIDECLQNGRICNNGRCIN--TDGSFHCVCNAGFHVTRDGKNCE 571
Query: 140 QADPCA-SNPCANGGQCLPFEASYICHCPPSFH----GPTCRQDVNECGQKPGLCRHGGT 194
D C+ N C N G C+ + S+ C C P F G C+ D+NEC + PG+C + G
Sbjct: 572 DMDECSIRNMCLN-GMCINEDGSFKCICKPGFQLASDGRYCK-DINEC-ETPGICMN-GR 627
Query: 195 CHNEVGSYRC-------------VCRATHTGPNCERPY---------------------- 219
C N GSYRC VC TH C Y
Sbjct: 628 CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCAS 687
Query: 220 ------VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACV 273
PC P P QN + + C+ PG T + N + C N G C
Sbjct: 688 TEYAFGEPCQPCPAQN------SAEYQALCSSGPGMTSAGSDINECALDPDICPN-GICE 740
Query: 274 DGVNTYNCRCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTG 329
+ TY C C + TG+ C D++EC L C N G C NT G + C C G+
Sbjct: 741 NLRGTYKCICNSGYEVDSTGKNCV-DINECVLNSLLCDN-GQCRNTPGSFVCTCPKGFIY 798
Query: 330 E---DCSENIDDCASAACFHGATCHDRVASFYCECPH----GRTGLLC------------ 370
+ E+ID+C S+ C +G C + SF CEC T +C
Sbjct: 799 KPDLKTCEDIDECESSPCING-VCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV 857
Query: 371 -------HLNDACISNPC---------NEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD 414
++N A + + C + + C +P+ GK S G C +D+D
Sbjct: 858 IDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY----SRIKGTQC-EDID 912
Query: 415 ECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRC-EIDVNEC------------V 457
EC + C++ G C+NT GSF+CQC G TG C +I + C +
Sbjct: 913 ECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 971
Query: 458 SNPCQNDATC----------------LDQIGEFQCICM--PGY------EGVHCEVNTDE 493
+ + DA C + E++ +C PG+ G + +E
Sbjct: 972 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
Query: 494 CASSP--CLHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECASTP--CKNGAKCLD 545
C P C H G+C + I F+C C +GF C D+DEC +P C G +C++
Sbjct: 1032 CKMIPSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNCT-DIDECRISPDLCGRG-QCVN 1088
Query: 546 GPNTYTCVCTEGYTG-----THCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGH 598
P + C C EGY +C +DIDEC DP C G C + ++ C C P GH
Sbjct: 1089 TPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPP---GH 1144
Query: 599 HCETNINEC--------SSQPCRHGGTCQDRDNAYLCFCLKG---TTGPNCEINLDDCA- 646
NI+ C S+ C + G C + Y C C G T +++D+C+
Sbjct: 1145 QLSPNISACIDINECELSAHLCPN-GRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI 1203
Query: 647 -SSPCDSGTCLDKIDGYECACEPGYT---GSMCNINIDECAGNP-CHNGGTCEDGINGFT 701
+ C++ C + YEC+C+PG+ +IDEC NP +GG C + +
Sbjct: 1204 MNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYR 1262
Query: 702 CRCPEGY---HDPTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWSG----TNC-D 751
C C +G+ D +VNEC+ NP C+ G C ++ + C CD G+SG T C D
Sbjct: 1263 CLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTD 1322
Query: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ-TNINECA--SNPCLNQGTCID 808
IN E ++ C C + + C+C G+ G + T+++EC+ ++ C C +
Sbjct: 1323 INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKN 1382
Query: 809 DVAGYKCNCLLPYT--GATCEVVLAPCAP--SPCRNGGECRQSEDYESFSCVCPTGW--- 861
+ Y+C C YT G TC L C+ + C N G+C + + C C G+
Sbjct: 1383 TMGSYRCLCKEGYTGDGFTC-TDLDECSENLNLCGN-GQCLNAPG--GYRCECDMGFVPS 1438
Query: 862 -QGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCRPNPC 916
G+ CE DI+EC L +C N G +RC C+ GY SG NC TD+++C
Sbjct: 1439 ADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTT 1496
Query: 917 HNGGSCTDGINTAFCDCLPGF-----------------------RG----TFCEEDINE- 948
G+C + + CDC P F RG T C +I
Sbjct: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
Query: 949 ------CASDPCRNGANCTDC----VDSYTCTCPAGFSGIHCE------NNTPDCTE-SS 991
C S G C C Y CP G G + +C E
Sbjct: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGG-EGFRPNPITVILEDIDECQELPG 1615
Query: 992 CFNGGTCVDGINSFTCLCPPGF---TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCP 1048
GG C++ SF C CP G+ + DVNEC++ GTC + G+Y C CP
Sbjct: 1616 LCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICP 1675
Query: 1049 QGYT----GPNCQNL-------VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVP 1097
Y G NC ++ ++ D+ C G+ T+ C C S G + P
Sbjct: 1676 PDYMQVNGGNNCMDMRRSLCYRNYYADNQTC--DGELLFNMTKKMC-CCSYNIGRAWNKP 1732
Query: 1098 SVSCEVAAQRQGVDVARLC--QHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS--PSP 1153
C + + + A LC Q G +D YTG + +DEC P
Sbjct: 1733 CEQCPIPSTD---EFATLCGSQRPGFVIDI-----------YTGLPVD--IDECREIPGV 1776
Query: 1154 CQNGATCTDYLGGYSCKCVAGY---HGVNCSEEIDECLSHP-CQNGGTCLDLPNTYKCSC 1209
C+NG C + +G + C+C G+ + E+IDEC + P CQ C++ +Y+C C
Sbjct: 1777 CENG-VCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC 1835
Query: 1210 PRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVN 1269
G + + CN + P ++G C+D VG + C C GF + D
Sbjct: 1836 KPGYRFT----STGQCNDR-NECQEIPNICSHGQCIDTVGSFYCLCHTGF---KTNDDQT 1887
Query: 1270 ECLS-NPC--DARGTQNCVQRVNDFHCECRAGHTGRRCESVIN-----GCKGKPCKNGGT 1321
CL N C DA G C + F+C C G I+ G C+NG
Sbjct: 1888 MCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNG-- 1945
Query: 1322 CAVASNTARGFICKCPAGFEGATCENDARTCGSL-RCL------NGGTCISGPRSPTCLC 1374
NT F C+C G+E A D RTC + CL GTC + S C+C
Sbjct: 1946 --QCINTVGSFQCQCNEGYEVAP---DGRTCVDINECLLEPRKCAPGTCQNLDGSYRCIC 2000
Query: 1375 LGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKF----NGLLCHILDY 1430
++ + C+ GTC T S ++CLCP F +G C L
Sbjct: 2001 PPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGS--FKCLCPEGFSLSSSGRRCQDLRM 2058
Query: 1431 S-----FGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFND 1485
S F GG C P+ + + + C C GW G C L +
Sbjct: 2059 SYCYAKFEGG------------KCSSPKSRNHSKQECC---CALKGEGW-GDPCELCPTE 2102
Query: 1486 P 1486
P
Sbjct: 2103 P 2103
Score = 475 bits (1223), Expect = e-133
Identities = 463/1692 (27%), Positives = 664/1692 (39%), Gaps = 404/1692 (23%)
Query: 55 PRCQDPNPCLSTP--CKNAGTCHVVDRRGVADYACSCALGF---SGPLCLTPLDNACLTN 109
P +D N C P C + G C R + + C C GF S T +D ++
Sbjct: 1024 PFFKDINECKMIPSLCTH-GKC----RNTIGSFKCRCDSGFALDSEERNCTDIDECRISP 1078
Query: 110 PCRNGGTCDLLTLTEYKCRCPPGWSG-----KSCQQADPCASNPC-ANGGQCLPFEASYI 163
G C + T +++C+C G+ K+C D C +P GG C E SY
Sbjct: 1079 DLCGRGQC-VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYR 1137
Query: 164 CHCPPSFH-GPTCRQ--DVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYV 220
C CPP P D+NEC LC +G C N +G Y+C C + V
Sbjct: 1138 CECPPGHQLSPNISACIDINECELSAHLCPNG-RCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Query: 221 PCSPSPCQNGG--TCRPTGDVTHECACLPGFT---GQNCEENIDDCPGN-NCKNGGACVD 274
NGG T + ++EC+C PGF Q +ID+C N N +GG C +
Sbjct: 1197 DIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTN 1256
Query: 275 GVNTYNCRCPPEWTGQYCTED------VDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT 328
Y C C + G +ED V+EC L PN C +G TC NT G + C C G++
Sbjct: 1257 IPGEYRCLC---YDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFICHCDMGYS 1312
Query: 329 GED----CSENIDDCASAA--CFHGATCHDRVASFYCECPHG--RTGLLCHLNDACISNP 380
G+ C++ I++C A C A C + SF C C G G+ C D C +
Sbjct: 1313 GKKGKTGCTD-INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGT 1371
Query: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-QDVDECSLGANPCEHAGKCINTLGSFECQ 439
+ D G C C GYTG + D+DECS N C + G+C+N G + C+
Sbjct: 1372 HMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGN-GQCLNAPGGYRCE 1430
Query: 440 CLQGYT----GPRCE----------------------------------------IDVNE 455
C G+ G CE DVNE
Sbjct: 1431 CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNE 1490
Query: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGR---------CL 506
C+ C++ G + C C P +E V + S C + R C
Sbjct: 1491 CLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACS 1550
Query: 507 DKI-----------------------------NEFQCECP--TGFTGH---LCQYDVDEC 532
++I +E++ CP GF + + D+DEC
Sbjct: 1551 NEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDEC 1610
Query: 533 ASTP--CKNGAKCLDGPNTYTCVCTEGY---TGTHCEVDIDECD-PDPCHYGSCKDGVAT 586
P C+ G KC++ ++ C C GY T D++EC+ P C G+C + V
Sbjct: 1611 QELPGLCQGG-KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGN 1669
Query: 587 FTCLCRPGYT----GHHC----------------------------------ETNINECS 608
+TC+C P Y G++C NI
Sbjct: 1670 YTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAW 1729
Query: 609 SQPCRHGGTCQDRDNAYLC------FCLKGTTGPNCEINLDDCASSP--CDSGTCLDKID 660
++PC + A LC F + TG +++D+C P C++G C++ +
Sbjct: 1730 NKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTG--LPVDIDECREIPGVCENGVCINMVG 1787
Query: 661 GYECACEPGYTGS----MCNINIDECAGNP-CHNGGTCEDGINGFTCRCPEGYHDPTC-- 713
+ C C G+ + +C +IDEC P C C + + C C GY +
Sbjct: 1788 SFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ 1846
Query: 714 LSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWSGTNCD----INNNECESNPCVNGGT 767
++ NEC P C HG C D++ + C C G+ TN D ++ NECE + C NG T
Sbjct: 1847 CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFK-TNDDQTMCLDINECERDACGNG-T 1904
Query: 768 CKDMTSGYVCTCREGF--SGPNCQTNINECAS---NPCLNQGTCIDDVAGYKCNCLLPYT 822
C++ + C C GF S N +++ECAS N C N G CI+ V ++C C Y
Sbjct: 1905 CRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYE 1963
Query: 823 ----GATC----EVVLAP--CAPSPCRNGGECRQSEDYESFSCVCPTGW--QGQTCEVDI 870
G TC E +L P CAP C+N S+ C+CP G+ Q + CE DI
Sbjct: 1964 VAPDGRTCVDINECLLEPRKCAPGTCQNLDG--------SYRCICPPGYSLQNEKCE-DI 2014
Query: 871 NECVLSP--CRHGASCQNTHGGYRCHCQAGYS----GRNCETDIDDCRPNPCH---NGGS 921
+ECV P C G +C NT G ++C C G+S GR C+ D R + C+ GG
Sbjct: 2015 DECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSSGRRCQ----DLRMSYCYAKFEGGK 2069
Query: 922 CTD--GINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGI- 978
C+ N + +C +G + C ++P +++ CP G SGI
Sbjct: 2070 CSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPD----------EAFRQICPYG-SGII 2118
Query: 979 ----HCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF--TGSYCQHDVNECD-SQPCL 1031
+ +C E G C++ S+ C CP G+ G+ C D +EC PC
Sbjct: 2119 VGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECV-DTDECSVGNPC- 2176
Query: 1032 HGGTCQDGCGSYRCTCPQGYT-GP--NCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 1088
GTC++ G + CTC +G+ GP C++ ++ C +P +C T+ Y C+CP G
Sbjct: 2177 GNGTCKNVIGGFECTCEEGFEPGPMMTCED-INECAQNPLLCAFRCVNTYGSYECKCPVG 2235
Query: 1089 WTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCED 1144
+ L D E + D C + T+ C C GY G C D
Sbjct: 2236 YV-LREDRRMCKDEDECEEGKHDCTEKQME---CKNLIGTYMCICGPGYQRRPDGEGCVD 2291
Query: 1145 LVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP----------- 1191
+EC P C+NG C + G Y+C+C G+ S DECL +
Sbjct: 2292 -ENECQTKPGICENGR-CLNTRGSYTCECNDGF---TASPNQDECLDNREGYCFTEVLQN 2346
Query: 1192 -CQNGGTCLDLPNTYKCSCPRGTQ-GVHCEI------------------------NVDDC 1225
CQ G + + +C C G G HCEI ++D+C
Sbjct: 2347 MCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDEC 2406
Query: 1226 NPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNEC--LSNPCDAR 1279
+ V R NG CV+ G Y C C G+ G C D+NEC PC+
Sbjct: 2407 KV-IHDVCR------NGECVNDRGSYHCICKTGYTPDITGTSCV-DLNECNQAPKPCNFI 2458
Query: 1280 GTQNCVQRVNDFHCECRAGHT----GRRCESVINGCKGKPCKNGGTCAVASNTARGFICK 1335
C + C C G+ GR C+ ++ C K C NT GF CK
Sbjct: 2459 ----CKNTEGSYQCSCPKGYILQEDGRSCKD-LDECATKQHNCQFLCV---NTIGGFTCK 2510
Query: 1336 CPAGF--------EGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF----TGPEC 1383
CP GF + C +D CGS G C + P S TC C F TG C
Sbjct: 2511 CPPGFTQHHTSCIDNNECTSDINLCGSK-----GICQNTPGSFTCECQRGFSLDQTGSSC 2565
Query: 1384 Q---------------------FPASSP-----------CLGGNPCYNQGTCEPTS---E 1408
+ + S P C+ N C + C S
Sbjct: 2566 EDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNT 2625
Query: 1409 SPFYRCLCPAKF 1420
Y+C+CPA F
Sbjct: 2626 LGSYKCMCPAGF 2637
Score = 447 bits (1151), Expect = e-125
Identities = 459/1690 (27%), Positives = 640/1690 (37%), Gaps = 381/1690 (22%)
Query: 102 LDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSCQQADPCASNPCANG-GQCL 156
+ + C CRN T+ +KCRC G++ ++C D C +P G GQC+
Sbjct: 1035 IPSLCTHGKCRN-------TIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
Query: 157 PFEASYICHCPPSFHG-----PTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHT 211
+ C C + C D++EC + P LCR GG CHN GSYRC C H
Sbjct: 1088 NTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQ 1145
Query: 212 -GPN---------CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE---ENI 258
PN CE S C NG G ++CAC PG+ +I
Sbjct: 1146 LSPNISACIDINECE-----LSAHLCPNGRCVNLIGK--YQCACNPGYHSTPDRLFCVDI 1198
Query: 259 DDCPGNNCKNGGA---CVDGVNTYNCRCPPEWT---GQYCTEDVDECQLMPNACQNGGTC 312
D+C + NGG C + +Y C C P + Q D+DEC+ PN C +GG C
Sbjct: 1199 DEC---SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQC 1254
Query: 313 HNTHGGYNCVCVNGW-TGEDCSENID----DCASAACFHGATCHDRVASFYCECPHGRTG 367
N G Y C+C +G+ ED +D D C G TC + SF C C G +G
Sbjct: 1255 TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFICHCDMGYSG 1313
Query: 368 LLCHLNDACISNPCNEGS-NCDTNPV----NGKAICTCPSGYTGPACS-QDVDECSLGAN 421
I N C G+ NC + V G C+C G+ G D+DECS G +
Sbjct: 1314 KKGKTGCTDI-NECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTH 1372
Query: 422 PCEHAGKCINTLGSFECQCLQGYTGP--RCEIDVNECVS--NPCQNDATCLDQIGEFQCI 477
C C NT+GS+ C C +GYTG C D++EC N C N CL+ G ++C
Sbjct: 1373 MCSQHADCKNTMGSYRCLCKEGYTGDGFTC-TDLDECSENLNLCGN-GQCLNAPGGYRCE 1430
Query: 478 C----MPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGF----TGHLCQYDV 529
C +P +G CE + DEC+ G C + F+CEC G+ +G C DV
Sbjct: 1431 CDMGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCT-DV 1488
Query: 530 DECAS-TPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFT 588
+EC T C +G C++ P +Y C C + V + C+ G T
Sbjct: 1489 NECLDPTTCISG-NCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDT 1547
Query: 589 CLCRP---GYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI---NL 642
G + C ++ + PC + LC +G + ++
Sbjct: 1548 ACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDI 1607
Query: 643 DDCASSP--CDSGTCLDKIDGYECACEPGY----TGSMCNINIDECAGNPCHNGGTCEDG 696
D+C P C G C++ ++C C GY +C+ +++EC GTC +
Sbjct: 1608 DECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCD-DVNECETPGICGPGTCYNT 1666
Query: 697 INGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNC-DINNN 755
+ +TC CP Y +VN G NC D+ +
Sbjct: 1667 VGNYTCICPPDY------MQVN---------------------------GGNNCMDMRRS 1693
Query: 756 ECESNPCVNGGTCK-----DMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV 810
C N + TC +MT C C NI + PC D
Sbjct: 1694 LCYRNYYADNQTCDGELLFNMTKKMCC----------CSYNIGRAWNKPCEQCPIPSTDE 1743
Query: 811 AGYKCNCLLP------YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW--- 861
C P YTG ++ P C NG SF C CP G+
Sbjct: 1744 FATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINM---VGSFRCECPVGFFYN 1800
Query: 862 -QGQTCEVDINECVLSP-CRHGASCQNTHGGYRCHCQAGY---SGRNCETDIDDCR--PN 914
+ CE DI+EC P C+ A C NT G YRC C+ GY S C D ++C+ PN
Sbjct: 1801 DKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQC-NDRNECQEIPN 1858
Query: 915 PCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASDPCRNGANCTDCVDSYTCT 970
C + G C D + + +C C GF+ T C DINEC D C NG C + + S+ C
Sbjct: 1859 ICSH-GQCIDTVGSFYCLCHTGFKTNDDQTMC-LDINECERDACGNG-TCRNTIGSFNCR 1915
Query: 971 CPAGFSGIHCENNTPDCTESSCFNG-----GTCVDGINSFTCLCPPGF----TGSYCQHD 1021
C GF H N+ D E + NG G C++ + SF C C G+ G C D
Sbjct: 1916 CNHGFILSH-NNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCV-D 1973
Query: 1022 VNECDSQP--CLHGGTCQDGCGSYRCTCPQGYTGPN--CQNLVHWCDSSPCKNGGKCWQT 1077
+NEC +P C GTCQ+ GSYRC CP GY+ N C+++ + G C T
Sbjct: 1974 INECLLEPRKCA-PGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNT 2032
Query: 1078 HTQYRCECPSGWT---------------------GLYCDVPSV----------------- 1099
++C CP G++ G C P
Sbjct: 2033 EGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW 2092
Query: 1100 --SCEVAAQRQGVDVARLCQHG-------------------------GLCVDAGNTHHCR 1132
CE+ ++C +G G C++ ++ C
Sbjct: 2093 GDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCE 2152
Query: 1133 CQAGY--TGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVAGYH--GVNCSEEIDEC 1187
C GY G+ C D DECS +PC NG TC + +GG+ C C G+ + E+I+EC
Sbjct: 2153 CPFGYILAGNECVD-TDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCEDINEC 2210
Query: 1188 LSHPCQNGGTCLDLPNTYKCSCPRG----------TQGVHCEINVDDCNPPVDPVSRSPK 1237
+P C++ +Y+C CP G CE DC
Sbjct: 2211 AQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTE---------- 2260
Query: 1238 CFNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNP--CDARGTQNCVQRVNDF 1291
C + +G Y C C PG+ GE C D NEC + P C+ C+ +
Sbjct: 2261 --KQMECKNLIGTYMCICGPGYQRRPDGEGCV-DENECQTKPGICE---NGRCLNTRGSY 2314
Query: 1292 HCECRAGHTGR----RC----------ESVINGC-----------KGKPCKNGG------ 1320
CEC G T C E + N C K + C +GG
Sbjct: 2315 TCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH 2374
Query: 1321 --TCAVASNTARGFICKCPAGFEGATCENDARTCGSLR--CLNGGTCISGPRSPTCLCLG 1376
C A F CP G T D C + C N G C++ S C+C
Sbjct: 2375 CEICPFQGTVA--FKKLCPHGRGFMTNGADIDECKVIHDVCRN-GECVNDRGSYHCICKT 2431
Query: 1377 PFTGPECQFPASSPCLGGNPCYNQG------TCEPTSESPFYRCLCPAKF----NGLLCH 1426
+T P+ + C+ N C NQ C+ T S Y+C CP + +G C
Sbjct: 2432 GYT-PDI---TGTSCVDLNEC-NQAPKPCNFICKNTEGS--YQCSCPKGYILQEDGRSCK 2484
Query: 1427 ILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDP 1486
LD EC N C C N G+ C F
Sbjct: 2485 DLD-----------------------ECATKQHN--CQFLCVNTIGGFT-CKCPPGFTQH 2518
Query: 1487 WKNCTQSLQCWKYF----SDGHCDSQCNSAGCLFD-GFDCQRAEGQCNPLYDQYCKDHFS 1541
+C + +C S G C + S C GF + C + D+ +H
Sbjct: 2519 HTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV-DECEGNH-- 2575
Query: 1542 DGHCDQGCNS 1551
C GC +
Sbjct: 2576 --RCQHGCQN 2583
Score = 438 bits (1126), Expect = e-122
Identities = 468/1659 (28%), Positives = 648/1659 (39%), Gaps = 396/1659 (23%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
C+NGG C + C+C ++G C P + C N G C VA C+C
Sbjct: 123 CMNGGSCS----DDHCLCQKGYIGTHCGQP--VCESGCLNGGRC-------VAPNRCACT 169
Query: 91 LGFSGPLC---------LTPLDN----------------ACLT----------------N 109
GF+GP C T + N C T +
Sbjct: 170 YGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH 229
Query: 110 PCRNG-------GTCD-----------------LLTLTEYKCRCPPGWS----GKSCQQA 141
PCR G G C + T+ ++C+CP G + C+
Sbjct: 230 PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDI 289
Query: 142 DPCASNP-CANGGQCLPFEASYICHCPPSFHGPTCRQDVNEC-GQKPGLCRHG---GTCH 196
D C++ P GG+C +SY C CPP F+ D C +PG C G C
Sbjct: 290 DECSTIPGICEGGECTNTVSSYFCKCPPGFY---TSPDGTRCIDVRPGYCYTALTNGRCS 346
Query: 197 NE----VGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGT------CR------------ 234
N+ + +C C A C P V +P C T C
Sbjct: 347 NQLPQSITKMQCCCDAGR----CWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYP 402
Query: 235 --PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC 292
P G + PGF PG V+ + Y R PP
Sbjct: 403 PPPLGPIPPVLPVPPGFP-----------PGPQIPVPRPPVEYL--YPSREPPRVLPVNV 449
Query: 293 TEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSE--NIDDCASAACFHGATC 350
T D CQL+ CQN G C T G C C G+ + E ++D+C C G C
Sbjct: 450 T---DYCQLVRYLCQN-GRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPC-AGGEC 504
Query: 351 HDRVASFYCECPHGRTGLL----CHLNDACISNP--CNEGSNCDTNPVNGKAICTCPSGY 404
+ S+ C+C G L C D C+ N CN G +T +G C C +G+
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT---DGSFHCVCNAGF 561
Query: 405 ----TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNEC 456
G C +D+DECS+ N C + G CIN GSF+C C G+ G C+ D+NEC
Sbjct: 562 HVTRDGKNC-EDMDECSI-RNMCLN-GMCINEDGSFKCICKPGFQLASDGRYCK-DINEC 617
Query: 457 VSNPCQNDATCLDQIGEFQCICMPGYE-GVHCEVNTDECASSPC---LHNGRCL----DK 508
+ + C++ G ++C C PG G+ V D S C G+C+
Sbjct: 618 ETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGA 677
Query: 509 INEFQCECPTGFTGHLCQYDVDE-CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDI 567
+ + +C C + +Y E C P +N A+ Y +C+ G T DI
Sbjct: 678 VTKSECCCAS------TEYAFGEPCQPCPAQNSAE-------YQALCSSGPGMTSAGSDI 724
Query: 568 DEC--DPDPCHYGSCKDGVATFTCLCRPGY----TGHHCETNINEC--SSQPCRHGGTCQ 619
+EC DPD C G C++ T+ C+C GY TG +C +INEC +S C G C+
Sbjct: 725 NECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC-VDINECVLNSLLC-DNGQCR 782
Query: 620 DRDNAYLCFCLKG----TTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMC 675
+ +++C C KG CE ++D+C SSPC +G C + + C C T
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTCE-DIDECESSPCINGVCKNSPGSFICECSSESTLDPT 841
Query: 676 NINIDECAGNPCHN---GGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRD 732
E C G CE ING T + C S + +PC
Sbjct: 842 KTICIETIKGTCWQTVIDGRCEININGATLK-------SQCCSSLGAAWGSPCT------ 888
Query: 733 SLNGYKCDCDP----GWS---GTNCDINNNECESNPCV-NGGTCKDMTSGYVCTCREGFS 784
C DP G+S GT C+ + +ECE P V G C + + C C G +
Sbjct: 889 -----LCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMT 942
Query: 785 GPNCQTNINECASNPCLN--QGTCIDDVAGYKCNCLLPYTG-----ATCEVVLAPCAPSP 837
+ CL+ TC +C LP G A C V A
Sbjct: 943 --------LDATGRICLDIRLETCFLRYEDEECT--LPIAGRHRMDACCCSVGAAWGTEE 992
Query: 838 CRNGGEC--RQSEDYESFSCVCPTGWQGQTCEV--------DINECVLSP--CRHGASCQ 885
C EC R + +YE +CP G T E+ DINEC + P C HG C+
Sbjct: 993 CE---ECPMRNTPEYEE---LCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHG-KCR 1045
Query: 886 NTHGGYRCHCQAGYS----GRNCETDIDDCRPNPCHNG-GSCTDGINTAFCDCLPGFRGT 940
NT G ++C C +G++ RNC TDID+CR +P G G C + C C G+
Sbjct: 1046 NTIGSFKCRCDSGFALDSEERNC-TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESG 1104
Query: 941 FCE----EDINECASDP--CRNGANCTDCVDSYTCTCPAGFS---GIHCENNTPDCTESS 991
F DI+EC DP CR G C + SY C CP G I + +C S+
Sbjct: 1105 FMMMKNCMDIDECQRDPLLCRGGV-CHNTEGSYRCECPPGHQLSPNISACIDINECELSA 1163
Query: 992 --CFNGGTCVDGINSFTCLCPPGFTGS----YCQHDVNECDSQPCLHGGT---CQDGCGS 1042
C N G CV+ I + C C PG+ + +C D++EC ++GG C + GS
Sbjct: 1164 HLCPN-GRCVNLIGKYQCACNPGYHSTPDRLFCV-DIDECS---IMNGGCETFCTNSEGS 1218
Query: 1043 YRCTCPQGYT----GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPS 1098
Y C+C G+ +C ++ D+ +GG+C +YRC C G+ + S
Sbjct: 1219 YECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF------MAS 1272
Query: 1099 VSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTG----SYCEDLVD-ECSPSP 1153
+ D+ G C + + C C GY+G + C D+ + E
Sbjct: 1273 EDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHN 1332
Query: 1154 CQNGATCTDYLGGYSCKCVAGY--HGVNCSEEIDECL--SHPCQNGGTCLDLPNTYKCSC 1209
C A CT+ G + C C G+ G+ C+ ++DEC +H C C + +Y+C C
Sbjct: 1333 CGKHAVCTNTAGSFKCSCSPGWIGDGIKCT-DLDECSNGTHMCSQHADCKNTMGSYRCLC 1391
Query: 1210 PRG--TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV----GER 1263
G G C ++D+C S + NG C++ GGY C C GFV G+
Sbjct: 1392 KEGYTGDGFTC-TDLDEC-------SENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKA 1443
Query: 1264 CEGDVNEC-LSNPCDARGTQNCVQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKN 1318
CE D++EC L N C GT C F CEC G+ +G C V N C
Sbjct: 1444 CE-DIDECSLPNIC-VFGT--CHNLPGLFRCECEIGYELDRSGGNCTDV-NECLDPTTCI 1498
Query: 1319 GGTCAVASNTARGFICKCPAGFE------------GATCENDARTCGSLRCLNGGTCIS- 1365
G C NT +IC CP FE C D R G NG T S
Sbjct: 1499 SGNCV---NTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGD----NGDTACSN 1551
Query: 1366 ----GPRSPTCLC-LGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKF 1420
G +C C LG G C+ C P N TSE Y+ LCP
Sbjct: 1552 EIGVGVSKASCCCSLGKAWGTPCEM-----C----PAVN------TSE---YKILCP--- 1590
Query: 1421 NGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 1459
GG R P +I E ++ ECQE G
Sbjct: 1591 ------------GGEGFRPNPITVILE--DIDECQELPG 1615
Score = 244 bits (622), Expect = 1e-63
Identities = 293/1126 (26%), Positives = 431/1126 (38%), Gaps = 232/1126 (20%)
Query: 530 DECASTPCKNGAKCLDG----PNTYTCVCTEGYTGTHC-EVDIDECDPDPCHYGSCKDGV 584
++C C++ C DG PN C C G C I C+ + GSC D
Sbjct: 78 NQCIVPICRHS--CGDGFCSRPNM--CTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD- 132
Query: 585 ATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDD 644
CLC+ GY G HC + E C +GG C + C C G TGP CE D
Sbjct: 133 ---HCLCQKGYIGTHCGQPVCESG---CLNGGRCVAPNR---CACTYGFTGPQCE---RD 180
Query: 645 CASSPC----DSGTCLDKIDGYECA---------------CE-------PGYTGSMCNI- 677
+ PC + C ++ G C CE P G + NI
Sbjct: 181 YRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIR 240
Query: 678 -----NIDECAGNP--CHNGGTCEDGINGFTCRCPEGYH----DPTCLSEVNECNSNP-- 724
++DEC P C GG C + + F C+CP G+ C +++EC++ P
Sbjct: 241 TGACQDVDECQAIPGLCQ-GGNCINTVGSFECKCPAGHKLNEVSQKC-EDIDECSTIPGI 298
Query: 725 CVHGACRDSLNGYKCDCDPGW----SGTNC-DINNNECESNPCVNGGTCKDMTSGYV--- 776
C G C ++++ Y C C PG+ GT C D+ C + + G C + +
Sbjct: 299 CEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYT--ALTNGRCSNQLPQSITKM 356
Query: 777 -CTCREG---FSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP 832
C C G G + + N+ + V + P G V+ P
Sbjct: 357 QCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVP 416
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN---ECVLSPCRHGASCQNTHG 889
P R +Y + P+ + V++ + V C++G C T G
Sbjct: 417 PGFPPGPQIPVPRPPVEY-----LYPSREPPRVLPVNVTDYCQLVRYLCQNG-RCIPTPG 470
Query: 890 GYRCHCQAGY--SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCE---E 944
RC C G+ R D+D+C NPC GG C + + C C G++ T
Sbjct: 471 SCRCECNKGFQLDLRGECIDVDECEKNPC-AGGECINNQGSYTCQCRAGYQSTLTRTECR 529
Query: 945 DINECASDP--CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTC 998
DI+EC + C NG C + S+ C C AGF G +CE+ + C N G C
Sbjct: 530 DIDECLQNGRICNNG-RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLN-GMC 587
Query: 999 VDGINSFTCLCPPGF----TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY-TG 1053
++ SF C+C PGF G YC+ D+NEC++ G C + GSYRC C G G
Sbjct: 588 INEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCECFPGLAVG 646
Query: 1054 PNCQNLVHWCDSSPCKNG---GKC----WQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQ 1106
+ + V S C G G+C + T+ C C S T P C+
Sbjct: 647 LDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCAS--TEYAFGEP---CQPCPA 701
Query: 1107 RQGVDVARLCQHG----------------------GLCVDAGNTHHCRCQAGY----TGS 1140
+ + LC G G+C + T+ C C +GY TG
Sbjct: 702 QNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGK 761
Query: 1141 YCEDLVDEC--SPSPCQNGATCTDYLGGYSCKCVAGY---HGVNCSEEIDECLSHPCQNG 1195
C D ++EC + C NG C + G + C C G+ + E+IDEC S PC N
Sbjct: 762 NCVD-INECVLNSLLCDNG-QCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCIN- 818
Query: 1196 GTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC 1255
G C + P ++ C C +DP C++ + G TC
Sbjct: 819 GVCKNSPGSFICEC--------------SSESTLDPTKT--------ICIETIKG---TC 853
Query: 1256 PPGFVGERCEGDVN------ECLSNPCDARGTQNCVQRVNDFHCECRAGHT---GRRCES 1306
+ RCE ++N +C S+ A G+ + +V+ C G++ G +CE
Sbjct: 854 WQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPI---CGKGYSRIKGTQCED 910
Query: 1307 VINGCKGKP--CKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCI 1364
I+ C+ P CKNG + NT F C+CP+G T + R C +R TC
Sbjct: 911 -IDECEVFPGVCKNG----LCVNTRGSFKCQCPSGM---TLDATGRICLDIRL---ETCF 959
Query: 1365 SGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCE--PTSESPFYRCLCPAKFNG 1422
C P G + + C + CE P +P Y LCP G
Sbjct: 960 LRYEDEECTL--PIAG---RHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCP---RG 1011
Query: 1423 LLCHILDYSFGGGAGRDIPP-PLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSL 1481
+ + G +DI +I C +C+ G+ C +C D
Sbjct: 1012 PGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKC--RC----------DSGF 1059
Query: 1482 NFNDPWKNCTQSLQCWKYFSDGHCDSQC-NSAGCLFDGFDCQRAEG 1526
+ +NCT +C + D QC N+ G F+C+ EG
Sbjct: 1060 ALDSEERNCTDIDEC-RISPDLCGRGQCVNTPG----DFECKCDEG 1100
Score = 198 bits (503), Expect = 6e-50
Identities = 236/918 (25%), Positives = 326/918 (35%), Gaps = 228/918 (24%)
Query: 728 GACRDSLNG-------YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKD--MTSGYVCT 778
G D+L G Y C PGW N+C C + +C D + +CT
Sbjct: 47 GGGHDALKGPNVCGSRYNAYCCPGWKTLP---GGNQCIVPICRH--SCGDGFCSRPNMCT 101
Query: 779 CREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC 838
C G P+C + + + C+N G+C DD C C Y G C P S C
Sbjct: 102 CPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD----HCLCQKGYIGTHCG---QPVCESGC 154
Query: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH---C 895
NGG C C C G+ G CE D CQ G C C
Sbjct: 155 LNGGRCVAPN-----RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLC 209
Query: 896 QAGYS---GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
A G CE + +P+PC G +P R C +D++EC +
Sbjct: 210 CATVGRAWGHPCE--MCPAQPHPCRRG-------------FIPNIRTGAC-QDVDECQAI 253
Query: 953 P--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCF----NGGTCVDGINSFT 1006
P C+ G NC + V S+ C CPAG D E S GG C + ++S+
Sbjct: 254 PGLCQ-GGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYF 312
Query: 1007 CLCPPGFTGSYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCT--CPQGYTGPNCQNLVHWC 1063
C CPPGF Y D C D +P G C + RC+ PQ T C
Sbjct: 313 CKCPPGF---YTSPDGTRCIDVRP----GYCYTALTNGRCSNQLPQSITKMQC------- 358
Query: 1064 DSSPCKNGGKCWQTHTQYRCE-CPSGWT---GLYCDVPSV-------------------- 1099
C + G+CW E CP T C VP V
Sbjct: 359 ----CCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLP 414
Query: 1100 -------SCEVAAQRQGVD----------------------VARLCQHGGLCVDAGNTHH 1130
++ R V+ V LCQ+ G C+ +
Sbjct: 415 VPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQN-GRCIPTPGSCR 473
Query: 1131 CRCQAGY---TGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE---I 1184
C C G+ C D VDEC +PC G C + G Y+C+C AGY E I
Sbjct: 474 CECNKGFQLDLRGECID-VDECEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTECRDI 531
Query: 1185 DECLSH-PCQNGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPVDPVSRSPKCF 1239
DECL + N G C++ ++ C C G G +CE ++D+C S C
Sbjct: 532 DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDEC-------SIRNMCL 583
Query: 1240 NNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 1295
NG C+++ G + C C PGF G C+ D+NEC + G CV + CEC
Sbjct: 584 -NGMCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNG--RCVNTDGSYRCEC 639
Query: 1296 ----RAGHTGRRC------ESVINGCKGKPC--------KNGGTCAVASNTARGFICK-C 1336
G GR C + G K C C ++ A G C+ C
Sbjct: 640 FPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPC 699
Query: 1337 PAGFEG---ATCENDARTCGSLRCLN----------GGTCISGPRSPTCLCLGPF----T 1379
PA A C + + +N G C + + C+C + T
Sbjct: 700 PAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDST 759
Query: 1380 GPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRD 1439
G C + C+ + + G C T S + C CP F
Sbjct: 760 GKNC--VDINECVLNSLLCDNGQCRNTPGS--FVCTCPKGF------------------- 796
Query: 1440 IPPPLIEEACELPECQED-AGNKVCSLQCNNHACGWDGGDCSLNFN-DPWKN-CTQSLQ- 1495
I P ++ ++ EC+ N VC + C +CS DP K C ++++
Sbjct: 797 IYKPDLKTCEDIDECESSPCINGVCKNSPGSFIC-----ECSSESTLDPTKTICIETIKG 851
Query: 1496 -CWKYFSDGHCDSQCNSA 1512
CW+ DG C+ N A
Sbjct: 852 TCWQTVIDGRCEININGA 869
Score = 112 bits (280), Expect = 5e-24
Identities = 100/346 (28%), Positives = 147/346 (42%), Gaps = 62/346 (17%)
Query: 195 CHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNC 254
C + +Y C T G N + VP C +G RP + C C G +C
Sbjct: 59 CGSRYNAYCCPGWKTLPGGN--QCIVPICRHSCGDGFCSRP-----NMCTCPSGQIAPSC 111
Query: 255 -EENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCH 313
+I C C NGG+C D +C C + G +C + V E + C NGG C
Sbjct: 112 GSRSIQHC-NIRCMNGGSCSDD----HCLCQKGYIGTHCGQPVCE-----SGCLNGGRCV 161
Query: 314 NTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN 373
+ C C G+TG C + + C +++ C+ +G++C
Sbjct: 162 APN---RCACTYGFTGPQCERD---------YRTGPCFTVISNQMCQGQ--LSGIVCTKT 207
Query: 374 DACISNPCNEGSNCDTNPVNGKAICTCPSGY-----TGPACSQDVDECSLGANPCEHAGK 428
C + G C+ P C G+ TG AC QDVDEC C+ G
Sbjct: 208 LCCATVGRAWGHPCEMCPAQPHP---CRRGFIPNIRTG-AC-QDVDECQAIPGLCQ-GGN 261
Query: 429 CINTLGSFECQCLQGY----TGPRCEIDVNECVSNP--CQNDATCLDQIGEFQCICMPGY 482
CINT+GSFEC+C G+ +CE D++EC + P C+ C + + + C C PG+
Sbjct: 262 CINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEG-GECTNTVSSYFCKCPPGF 319
Query: 483 ----EGVHC-EVNTDECASSPCLHNGRCLDK----INEFQCECPTG 519
+G C +V C ++ L NGRC ++ I + QC C G
Sbjct: 320 YTSPDGTRCIDVRPGYCYTA--LTNGRCSNQLPQSITKMQCCCDAG 363
Score = 88.6 bits (218), Expect = 7e-17
Identities = 75/291 (25%), Positives = 110/291 (37%), Gaps = 48/291 (16%)
Query: 438 CQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASS 497
C C G P C + + C N +C D C+C GY G HC E S
Sbjct: 100 CTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD----HCLCQKGYIGTHCGQPVCE---S 152
Query: 498 PCLHNGRCLDKINEFQCECPTGFTGHLCQ--YDVDEC----ASTPCKNGAKCLDGPNTYT 551
CL+ GRC + +C C GFTG C+ Y C ++ C+ + T
Sbjct: 153 GCLNGGRC---VAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLC 209
Query: 552 CVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQP 611
C G CE+ P PC G + + T C +++EC + P
Sbjct: 210 CATVGRAWGHPCEMC--PAQPHPCRRGFIPN-IRTGAC------------QDVDECQAIP 254
Query: 612 --CRHGGTCQDRDNAYLCFCLKG----TTGPNCEINLDDCASSP--CDSGTCLDKIDGYE 663
C+ GG C + ++ C C G CE ++D+C++ P C+ G C + + Y
Sbjct: 255 GLCQ-GGNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYF 312
Query: 664 CACEPGYTGSMCNINIDECAGNPCH---NGGTCED----GINGFTCRCPEG 707
C C PG+ S + C+ G C + I C C G
Sbjct: 313 CKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 511 bits (1316), Expect = e-144
Identities = 468/1585 (29%), Positives = 676/1585 (42%), Gaps = 331/1585 (20%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPR----CQDPNPCLSTPCKNAGTCHVVDR 79
CS C NG KC GT C C + C D + C+ G C
Sbjct: 1204 CSLSDNLCRNG-KCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMN----GGCDTQCT 1258
Query: 80 RGVADYACSCALGFSGPLCLTPLDNACLT-NPCRN------GGTCDLLTLTEYKCRCPPG 132
Y CSC+ G++ L P +C + C N GG C + EY+C C G
Sbjct: 1259 NSEGSYECSCSEGYA----LMPDGRSCADIDECENNPDICDGGQCTNIP-GEYRCLCYDG 1313
Query: 133 WSG----KSCQQADPCA--SNPCANGGQCLPFEASYICHCPPSFH---GPTCRQDVNECG 183
+ K+C + C SN C G +C + S+ICHC + G T DV+EC
Sbjct: 1314 FMASMDMKTCIDVNECDLNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDECE 1372
Query: 184 QKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP-CSPSP--CQNGGTCRPTGDVT 240
C +C N GS++C CR G + + CS C C T +
Sbjct: 1373 IGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG-S 1431
Query: 241 HECACLPGFTGQNCE-ENIDDCPGN-NCKNGGACVDGVNTYNCRCPPEWT----GQYCTE 294
+ CAC GFTG ++D+C N N G C++ Y C C +T + C +
Sbjct: 1432 YRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC-Q 1490
Query: 295 DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW----TGEDCSENIDDCASAACFHGATC 350
D+DEC N C G TC+N G ++C+C +G+ TG +C++ ID+CA C
Sbjct: 1491 DIDECSFQ-NICVFG-TCNNLPGMFHCICDDGYELDRTGGNCTD-IDECADPINCVNGLC 1547
Query: 351 HDRVASFYCECP--------------------------HGRTGLLCHL--------NDAC 376
+ + C CP G L C+ + C
Sbjct: 1548 VNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCC 1607
Query: 377 ISNPCNEGSNCDT-NPVNGKAICT-CPSGY---TGPACS--QDVDECSLGANPCEHAGKC 429
S G+ C+T PVN T CP G P +D+DEC C+ G C
Sbjct: 1608 CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQ-GGNC 1666
Query: 430 INTLGSFECQCLQGYTGPR----CEIDVNECVSNP--CQNDATCLDQIGEFQCICMPGYE 483
INT GSF+C+C QGY CE D++EC ++P C TC + +G + CIC P Y
Sbjct: 1667 INTFGSFQCECPQGYYLSEDTRICE-DIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYM 1724
Query: 484 GVHCEVNTDECASSPCL--HNGRCLDKINEFQCECPTGFTGHLC--QYDVDECASTPCKN 539
V+ N + S C +NG + E P T +C Y+V + + PC+
Sbjct: 1725 QVNGGHNCMDMRKSFCYRSYNGTTCEN------ELPFNVTKRMCCCTYNVGKAWNKPCE- 1777
Query: 540 GAKC-LDGPNTYTCVCTE--GYT---GTHCEVDIDECDPDP--CHYGSCKDGVATFTCLC 591
C G + +C G+T T VDIDEC P C G C + + +F C C
Sbjct: 1778 --PCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCEC 1835
Query: 592 RPGYTGHH----CETNINECSSQP--CRHGGTCQDRDNAYLCFCLKG-TTGPNCE-INLD 643
G++ + CE +I+ECS+ C+ C + +Y C C G PN ++ +
Sbjct: 1836 PTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRN 1894
Query: 644 DCASSP--CDSGTCLDKIDGYECACEPGYTGS----MCNINIDECAGNPCHNGGTCEDGI 697
+C P C G C+D Y+C C G+ S MC +++DEC +PC NG TC++ +
Sbjct: 1895 ECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMC-MDVDECERHPCGNG-TCKNTV 1952
Query: 698 NGFTCRCPEGY---HDPTCLSEVNECNS---NPCVHGACRDSLNGYKCDCDPGWS----G 747
+ C C G+ H+ CL +++EC+S C +G C + + +KC C+ G+ G
Sbjct: 1953 GSYNCLCYPGFELTHNNDCL-DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDG 2011
Query: 748 TNCDINNNECESNP-CVNGGTCKDMTSGYVCTCREGFS--GPNCQTNINECASNP--CLN 802
NC I+ NEC + P + GTC+++ + C C G+ NC +INEC +P CL
Sbjct: 2012 KNC-IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENC-IDINECDEDPNICLF 2069
Query: 803 QGTCIDDVAGYKCNC----LLPYTGATC-----------------------EVVLAPCAP 835
G+C + G++C C +L G C A C
Sbjct: 2070 -GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCC 2128
Query: 836 SPCRNGG-----ECRQSEDYESFSCVCPTGWQG----QTCEVDINECVLSP--CRHGASC 884
S G E +D +F +CP G D+NEC+ SP C +G C
Sbjct: 2129 SKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNG-QC 2187
Query: 885 QNTHGGYRCHCQAGYS----GRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFR- 938
NT G +RC C GY+ G C D D+C NPC NG +CT+ I + C+C GF
Sbjct: 2188 INTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEP 2245
Query: 939 GTFCE-EDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS-----C 992
G EDINECA +P C + SY CTCP G++ + D E + C
Sbjct: 2246 GPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDC 2305
Query: 993 FNGGT-CVDGINSFTCLCPPGFT----GSYCQHDVNECDSQPCL-HGGTCQDGCGSYRCT 1046
+ G C + I +F C+CPPG G C D NEC ++P + G C + GSYRC
Sbjct: 2306 ESRGMMCKNLIGTFMCICPPGMARRPDGEGCV-DENECRTKPGICENGRCVNIIGSYRCE 2364
Query: 1047 CPQGY----TGPNC-------------QNLVHWCDSSP--------CKNGGKCWQTHTQY 1081
C +G+ +G C Q + SS C +GG+ W +
Sbjct: 2365 CNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWG----H 2420
Query: 1082 RCE-CPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH---GGLCVDAGNTHHCRCQAGY 1137
+CE CP T Y + + +D ++ + G C++ + C C+ GY
Sbjct: 2421 QCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGY 2480
Query: 1138 T----GSYCEDLVDECSPSP------CQN------------------GATCTDY------ 1163
T G+ C DL DECS SP C+N G TC D
Sbjct: 2481 TTDISGTSCIDL-DECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTK 2539
Query: 1164 -----------LGGYSCKCVAGY--HGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCS 1208
LGG++CKC G+ H C + +EC S P C G C + P ++ C
Sbjct: 2540 QHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDN-NECGSQPSLCGAKGICQNTPGSFSCE 2598
Query: 1209 CPRG----TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE-- 1262
C RG G++CE +VD+C+ + +C + C + +GGY C CP G++
Sbjct: 2599 CQRGFSLDATGLNCE-DVDECDG-------NHRCQHG--CQNILGGYRCGCPQGYIQHYQ 2648
Query: 1263 --RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESV---INGCKGK--P 1315
+C D NEC SNP +A G+ +C + + C C +G + + S +N C P
Sbjct: 2649 WNQCV-DENEC-SNP-NACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNP 2705
Query: 1316 CKNGGTCAVASNTARGFICKCPAGF 1340
C G SNT G++C CP G+
Sbjct: 2706 CNYG-----CSNTEGGYLCGCPPGY 2725
Score = 481 bits (1239), Expect = e-135
Identities = 468/1726 (27%), Positives = 682/1726 (39%), Gaps = 380/1726 (22%)
Query: 10 CLALLPALAARGPRCSQPG----ETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLS 65
C A+ A C +PG ET G A G V G P +D N C +
Sbjct: 1026 CCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGD---VLTGR---PFYKDINECKA 1079
Query: 66 TPCK-NAGTCHVVDRRGVADYACSCALGFSGPL----CLTPLDNACLTNPCRNGGTCDLL 120
P G C R + + C C GF+ + C T +D ++ G C +
Sbjct: 1080 FPGMCTYGKC----RNTIGSFKCRCNSGFALDMEERNC-TDIDECRISPDLCGSGIC-VN 1133
Query: 121 TLTEYKCRCPPGWSG-----KSCQQADPCASNPC-ANGGQCLPFEASYICHCPPSFHGPT 174
T ++C C G+ K+C D C NP GG C+ E S+ C CP
Sbjct: 1134 TPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSP 1193
Query: 175 CRQD---VNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGG 231
R+D +NEC LCR+G C N +G+Y+C C + + NGG
Sbjct: 1194 SREDCVDINECSLSDNLCRNG-KCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG 1252
Query: 232 --TCRPTGDVTHECACLPGFT----GQNCEENIDDCPGN-NCKNGGACVDGVNTYNCRCP 284
T + ++EC+C G+ G++C + ID+C N + +GG C + Y C C
Sbjct: 1253 CDTQCTNSEGSYECSCSEGYALMPDGRSCAD-IDECENNPDICDGGQCTNIPGEYRCLCY 1311
Query: 285 PEWTGQYCTE---DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT---GEDCSENIDD 338
+ + DV+EC L N C G C NT G + C C G++ G ++D+
Sbjct: 1312 DGFMASMDMKTCIDVNECDLNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDE 1370
Query: 339 CASAA--CFHGATCHDRVASFYCECPHG--RTGLLCHLNDACIS--NPCNEGSNCDTNPV 392
C A C A+C + SF C C G G+ C D C + + C+ + C P
Sbjct: 1371 CEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTP- 1429
Query: 393 NGKAICTCPSGYTGPA--CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----G 446
G C C G+TG CS DVDEC+ N CE+ G+C+N G++ C+C G+T
Sbjct: 1430 -GSYRCACSEGFTGDGFTCS-DVDECAENINLCEN-GQCLNVPGAYRCECEMGFTPASDS 1486
Query: 447 PRCEIDVNEC------VSNPCQN-----------------------------------DA 465
C+ D++EC V C N +
Sbjct: 1487 RSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNG 1545
Query: 466 TCLDQIGEFQCICMPGYE----GVHC------------------------EVNTDECASS 497
C++ G ++C C P ++ GV C E+ SS
Sbjct: 1546 LCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSS 1605
Query: 498 PCLHNGRCLDK---------INEFQCECP--TGFTGH---LCQYDVDECASTP--CKNGA 541
C G+ E+ CP GF + + D+DEC P C+ G
Sbjct: 1606 CCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGG- 1664
Query: 542 KCLDGPNTYTCVCTEGYTGTH----CEVDIDEC--DPDPCHYGSCKDGVATFTCLCRPGY 595
C++ ++ C C +GY + CE DIDEC P C G+C + + +TC+C P Y
Sbjct: 1665 NCINTFGSFQCECPQGYYLSEDTRICE-DIDECFAHPGVCGPGTCYNTLGNYTCICPPEY 1723
Query: 596 T----GHHCET--------------------------------NINECSSQPCRHGGTCQ 619
GH+C N+ + ++PC T
Sbjct: 1724 MQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPG 1783
Query: 620 DRDNAYLCFCLKGTT---GPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYTGS- 673
D +C + G T +++D+C P C +G C+++I + C C G++ +
Sbjct: 1784 TADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYND 1843
Query: 674 ---MCNINIDECAG--NPCHNGGTCEDGINGFTCRCPEGYH---DPTCLSEVNECNSNP- 724
+C +IDEC+ N C C + + C C G+ + C+ NEC P
Sbjct: 1844 LLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDR-NECLEIPN 1901
Query: 725 -CVHGACRDSLNGYKCDCDPGWSG----TNCDINNNECESNPCVNGGTCKDMTSGYVCTC 779
C HG C D Y+C C G+ T C ++ +ECE +PC NG TCK+ Y C C
Sbjct: 1902 VCSHGLCVDLQGSYQCICHNGFKASQDQTMC-MDVDECERHPCGNG-TCKNTVGSYNCLC 1959
Query: 780 REGF--SGPNCQTNINECAS---NPCLNQGTCIDDVAGYKCNCLLPYT----GATC---- 826
GF + N +I+EC+S C N G C +++ +KC C Y G C
Sbjct: 1960 YPGFELTHNNDCLDIDECSSFFGQVCRN-GRCFNEIGSFKCLCNEGYELTPDGKNCIDTN 2018
Query: 827 EVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQ--GQTCEVDINECVLSP--CRHGA 882
E V P + SP G C+ E SF C+CP G++ + C +DINEC P C G
Sbjct: 2019 ECVALPGSCSP----GTCQNLEG--SFRCICPPGYEVKSENC-IDINECDEDPNICLFG- 2070
Query: 883 SCQNTHGGYRCHCQAGY----SGRNCE--------TDIDD-----------------CRP 913
SC NT GG++C C G+ +GR C T+ ++ C
Sbjct: 2071 SCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSK 2130
Query: 914 NPCHNGGS----CTDGINTAFCDCLPGFRGTF-----CEEDINECASDP--CRNGANCTD 962
P G C AF D P GT ED+NEC P C NG C +
Sbjct: 2131 MPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNG-QCIN 2189
Query: 963 CVDSYTCTCPAGFS----GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
S+ C CP G++ G+ C + T +C+ + GTC + I SF C C GF
Sbjct: 2190 TDGSFRCECPMGYNLDYTGVRCVD-TDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPM 2248
Query: 1019 QH--DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTG----------PNCQNLVHWCDSS 1066
+ D+NEC P L C + GSY CTCP GY C +H C+S
Sbjct: 2249 MNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCES- 2307
Query: 1067 PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG 1126
G C + C CP G V + G+ C++G CV+
Sbjct: 2308 ---RGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGI-----CENGR-CVNII 2358
Query: 1127 NTHHCRCQAGY----TGSYCED-----LVDECSPSPCQNGATCTDYLGGYSCKCVAGY-- 1175
++ C C G+ +G+ C D E + CQ ++ + + C C G
Sbjct: 2359 GSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGW 2418
Query: 1176 --------------------HGVNCS---EEIDECLSHP--CQNGGTCLDLPNTYKCSCP 1210
HG + +IDEC P C NG C++ +++C C
Sbjct: 2419 GHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG-QCINTMGSFRCFCK 2477
Query: 1211 RG----TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV----GE 1262
G G C I++D+C S+SPK N C + G Y C+CP G+V G+
Sbjct: 2478 VGYTTDISGTSC-IDLDEC-------SQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGK 2528
Query: 1263 RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTC 1322
C+ D++EC + + + CV + F C+C G T + N G G
Sbjct: 2529 TCK-DLDECQTKQHNCQFL--CVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAK 2585
Query: 1323 AVASNTARGFICKCPAGFE----GATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 1378
+ NT F C+C GF G CE+ G+ RC +G I G C C +
Sbjct: 2586 GICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILG--GYRCGCPQGY 2643
Query: 1379 TGPECQFPASSPCLGGNPCYNQGTCEPTS---ESPFYRCLCPAKFN 1421
Q + C+ N C N C S Y+C CP+ F+
Sbjct: 2644 ----IQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFS 2685
Score = 459 bits (1182), Expect = e-128
Identities = 473/1690 (27%), Positives = 692/1690 (40%), Gaps = 365/1690 (21%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF---VGPRCQDPNPCLSTPCKNAGTCHVVDRR 80
C CLNG +C + C C + C D + C S PC N G C V+
Sbjct: 498 CKHHANLCLNG-RCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTN-GDC--VNTP 553
Query: 81 GVADYACSCALGFSGPLCLTPLDNACL-TNPC-RNGGTCD----LLTLTEYKCRCPPGW- 133
G Y C C GF TP AC+ + C +NG C + T ++C C G+
Sbjct: 554 G--SYYCKCHAGFQ----RTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFE 607
Query: 134 ---SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKP 186
GK+C D C + G C+ + S+ C C P F +G C DV+EC Q P
Sbjct: 608 LTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYC-TDVDEC-QTP 665
Query: 187 GLCRHGGTCHNEVGSYRC-------------VCRATHTGPN---------CERPY----- 219
G+C + G C N GS+RC VC TH C RP+
Sbjct: 666 GICMN-GHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVT 724
Query: 220 --------------VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNN 265
PC P P +N + + C+ G T + N +
Sbjct: 725 KSECCCANPDYGFGEPCQPCPAKN------SAEFHGLCSSGVGITVDGRDINECALDPDI 778
Query: 266 CKNGGACVDGVNTYNCRC----PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNC 321
C N G C + +Y C C P+ +G+ C D+DEC + C N G C NT G Y+C
Sbjct: 779 CAN-GICENLRGSYRCNCNSGYEPDASGRNCI-DIDECLVNRLLCDN-GLCRNTPGSYSC 835
Query: 322 VCVNGW---TGEDCSENIDDCASAACFHGATCHDRVASFYCECPHG----RTGLLC--HL 372
C G+ T + E+I++C S C +GA C + + SF CEC G TGL+C L
Sbjct: 836 TCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLGSFNCECSPGSKLSSTGLICIDSL 894
Query: 373 NDACISNPCNEGSNCDTNPVNG---KAIC-------------------TCPSGYT---GP 407
C N + S C+ N +NG K+ C CP G G
Sbjct: 895 KGTCWLN--IQDSRCEVN-INGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGV 951
Query: 408 ACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRC-EIDVNECVSNPCQ 462
C +DV+EC + C + G+C+N+ GSF C+C +G TG C +I + +C
Sbjct: 952 TC-EDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLK--W 1007
Query: 463 NDATCLDQI-GEFQ---CICMPGYE-GVHCEVNTDECASSPCLHNGRCLDKINEFQCECP 517
++ C+ + G+F+ C C G G CE EC E++ CP
Sbjct: 1008 DEDECIHPVPGKFRMDACCCAVGAAWGTECE----ECPK----------PGTKEYETLCP 1053
Query: 518 TG---------FTGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYT----GTH 562
G TG D++EC + P C G KC + ++ C C G+ +
Sbjct: 1054 RGAGFANRGDVLTGRPFYKDINECKAFPGMCTYG-KCRNTIGSFKCRCNSGFALDMEERN 1112
Query: 563 CEVDIDEC--DPDPCHYGSCKDGVATFTCLCRPGYTG-----HHCETNINECSSQP--CR 613
C DIDEC PD C G C + +F C C GY +C +I+EC P CR
Sbjct: 1113 C-TDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNC-MDIDECERNPLLCR 1170
Query: 614 HGGTCQDRDNAYLCFCLKG-TTGPNCE--INLDDCASSP--CDSGTCLDKIDGYECACEP 668
GGTC + + ++ C C G P+ E +++++C+ S C +G C++ I Y+C+C P
Sbjct: 1171 -GGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNP 1229
Query: 669 GYTGSMCN---INIDECAGNPCHNGG---TCEDGINGFTCRCPEGY---HDPTCLSEVNE 719
GY + +IDEC NGG C + + C C EGY D ++++E
Sbjct: 1230 GYQATPDRQGCTDIDECM---IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDE 1286
Query: 720 CNSNP--CVHGACRDSLNGYKCDCDPGWSG-----TNCDINNNECESNPCVNGGTCKDMT 772
C +NP C G C + Y+C C G+ T D+N + SN C+ G C++
Sbjct: 1287 CENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICM-FGECENTK 1345
Query: 773 SGYVCTCREGFS---GPNCQTNINEC--ASNPCLNQGTCIDDVAGYKCNCLLPYTGATCE 827
++C C+ G+S G T+++EC ++ C +C++ +KC+C + G +
Sbjct: 1346 GSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK 1405
Query: 828 VV-LAPCA--PSPCRNGGECRQSEDYESFSCVCPTGWQGQ--TCEVDINECV--LSPCRH 880
+ L C+ C +C + S+ C C G+ G TC D++EC ++ C +
Sbjct: 1406 CIDLDECSNGTHQCSINAQCVNTPG--SYRCACSEGFTGDGFTCS-DVDECAENINLCEN 1462
Query: 881 GASCQNTHGGYRCHCQAGYS----GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPG 936
G C N G YRC C+ G++ R+C+ DID+C G+C + C C G
Sbjct: 1463 G-QCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDG 1520
Query: 937 FR----GTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGF----SGIHC-ENNTP 985
+ G C DI+ECA DP C NG C + Y C CP F +G+ C +N
Sbjct: 1521 YELDRTGGNC-TDIDECA-DPINCVNGL-CVNTPGRYECNCPPDFQLNPTGVGCVDNRVG 1577
Query: 986 DC----------------------TESSCFN------GGTC--VDGINS--FTCLCP--P 1011
+C + SSC G C +NS + LCP
Sbjct: 1578 NCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGE 1637
Query: 1012 GFTG---SYCQHDVNECDSQPCL-HGGTCQDGCGSYRCTCPQGYTGPN----CQNLVHWC 1063
GF + D++EC P L GG C + GS++C CPQGY C++ + C
Sbjct: 1638 GFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICED-IDEC 1696
Query: 1064 DSSPCKNG-GKCWQTHTQYRCECPSGWTGL--------------YCDVPSVSCEVAAQRQ 1108
+ P G G C+ T Y C CP + + Y +CE
Sbjct: 1697 FAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFN 1756
Query: 1109 GVDVARLCQHG---------GLCVDAGNTHHCRCQAGYTGSYCEDL-------VDECS-- 1150
C + C G T + G + D+ +DEC
Sbjct: 1757 VTKRMCCCTYNVGKAWNKPCEPCPTPG-TADFKTICGNIPGFTFDIHTGKAVDIDECKEI 1815
Query: 1151 PSPCQNGATCTDYLGGYSCKCVAGYHG---VNCSEEIDECLS--HPCQNGGTCLDLPNTY 1205
P C NG C + +G + C+C G+ + E+IDEC + + CQ C++ P +Y
Sbjct: 1816 PGICANG-VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSY 1874
Query: 1206 KCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
+C C G +++ + + P ++G CVD G Y C C GF + +
Sbjct: 1875 RCECAAG-----FKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQ 1929
Query: 1266 G---DVNECLSNPCDARGTQNCVQRVNDFHCECRAGH--TGRRCESVINGCK---GKPCK 1317
DV+EC +PC G C V ++C C G T I+ C G+ C+
Sbjct: 1930 TMCMDVDECERHPC---GNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCR 1986
Query: 1318 NGGTCAVASNTARGFICKCPAGFE----GATCENDARTCGSL-RCLNGGTCISGPRSPTC 1372
NG N F C C G+E G C D C +L + GTC + S C
Sbjct: 1987 NGR----CFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLEGSFRC 2041
Query: 1373 LCLGPFTGPECQFPASSPCLGGNPCYNQ------GTCEPTSESPFYRCLCPAKF----NG 1422
+C P S C+ N C G+C T+ ++CLCP F NG
Sbjct: 2042 IC------PPGYEVKSENCIDINECDEDPNICLFGSC--TNTPGGFQCLCPPGFVLSDNG 2093
Query: 1423 LLCHILDYSF 1432
C SF
Sbjct: 2094 RRCFDTRQSF 2103
Score = 458 bits (1178), Expect = e-128
Identities = 464/1671 (27%), Positives = 654/1671 (39%), Gaps = 388/1671 (23%)
Query: 104 NACLTNPCRNGGTCDLLTLTEYKCRCPPGW---SGKSCQQADPCASNPCANGGQCLPFEA 160
N CL C + T++ Y+C C G+ + C D C SNPC N G C+
Sbjct: 503 NLCLNGRC-------IPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTN-GDCVNTPG 554
Query: 161 SYICHCPPSFHGPTCRQ---DVNECGQKPGLCRHGGTCHNEVGSYRCVCRA----THTGP 213
SY C C F +Q D++EC Q LC++ G C N GS++C+C A T G
Sbjct: 555 SYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKN-GRCVNTDGSFQCICNAGFELTTDGK 613
Query: 214 NCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF----TGQNCEENIDDCPGNNCKNG 269
NC + + C NG G + +C C PGF G+ C + +D+C
Sbjct: 614 NCVDHDECTTTNMCLNGMCINEDG--SFKCICKPGFVLAPNGRYCTD-VDECQTPGICMN 670
Query: 270 GACVDGVNTYNCRCPP----EWTGQYCTEDVDECQLMPNACQNG---GTCHNTHGG---- 318
G C++ ++ C CPP G+ C + M + C G G C G
Sbjct: 671 GHCINSEGSFRCDCPPGLAVGMDGRVCVD-----THMRSTCYGGIKKGVCVRPFPGAVTK 725
Query: 319 YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACI 377
C C N G + C + A H +S GR C L+ D C
Sbjct: 726 SECCCANPDYGFG-----EPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICA 780
Query: 378 SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ---DVDECSLGANPCEHAGKCINTLG 434
+ C + G C C SGY A + D+DEC + C++ G C NT G
Sbjct: 781 NGICEN--------LRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDN-GLCRNTPG 831
Query: 435 SFECQCLQGYT----GPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPG--------- 481
S+ C C GY CE D+NEC SNPC N A C + +G F C C PG
Sbjct: 832 SYSCTCPPGYVFRTETETCE-DINECESNPCVNGA-CRNNLGSFNCECSPGSKLSSTGLI 889
Query: 482 ------------YEGVHCEVNTD------ECAS-------SPCLHNGRCLDKINEFQCEC 516
+ CEVN + EC + SPC RC E C
Sbjct: 890 CIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPC---ERC-----ELDTAC 941
Query: 517 PTGFT---GHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYT--GT-------- 561
P G G C+ DV+EC P C NG +C++ ++ C C EG T GT
Sbjct: 942 PRGLARIKGVTCE-DVNECEVFPGVCPNG-RCVNSKGSFHCECPEGLTLDGTGRVCLDIR 999
Query: 562 ----HCEVDIDEC----------DPDPCHYGSC---------KDGVATFTCLCRPG---- 594
+ + D DEC D C G+ K G + LC G
Sbjct: 1000 MEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFA 1059
Query: 595 -----YTGHHCETNINECSSQP--CRHGGTCQDRDNAYLCFCLKG----TTGPNCEINLD 643
TG +INEC + P C + G C++ ++ C C G NC ++D
Sbjct: 1060 NRGDVLTGRPFYKDINECKAFPGMCTY-GKCRNTIGSFKCRCNSGFALDMEERNC-TDID 1117
Query: 644 DCASSP--CDSGTCLDKIDGYECACEPGY-TGSMCNIN---IDECAGNP-CHNGGTCEDG 696
+C SP C SG C++ +EC C GY +G M N IDEC NP GGTC +
Sbjct: 1118 ECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNT 1177
Query: 697 INGFTCRCPEGYH-DPT---CLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWSGTNC 750
F C CP G+ P+ C+ ++NEC + N C +G C + + Y+C C+PG+ T
Sbjct: 1178 EGSFQCDCPLGHELSPSREDCV-DINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPD 1236
Query: 751 DINNNECESNPCVNGG---TCKDMTSGYVCTCREGFS----GPNCQTNINECASNPCL-N 802
+ + +NGG C + Y C+C EG++ G +C +I+EC +NP + +
Sbjct: 1237 RQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-ADIDECENNPDICD 1295
Query: 803 QGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQ 862
G C + Y+C C Y G + + C
Sbjct: 1296 GGQCTNIPGEYRCLC---YDGFMASMDMKTC----------------------------- 1323
Query: 863 GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYS---GRNCETDIDDCR--PNP 915
+D+NEC L+ C G C+NT G + CHCQ GYS G TD+D+C +
Sbjct: 1324 -----IDVNECDLNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHN 1377
Query: 916 CHNGGSCTDGINTAFCDCLPGFRGTFCE-EDINECA--SDPCRNGANCTDCVDSYTCTCP 972
C SC + + C C G+ G + D++EC+ + C A C + SY C C
Sbjct: 1378 CDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACS 1437
Query: 973 AGFS--GIHCENNTPDCTES-SCFNGGTCVDGINSFTCLCPPGFT----GSYCQHDVNEC 1025
GF+ G C ++ +C E+ + G C++ ++ C C GFT CQ D++EC
Sbjct: 1438 EGFTGDGFTC-SDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDEC 1495
Query: 1026 DSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSPCKNGGKCWQTHTQY 1081
Q GTC + G + C C GY TG NC ++ D C N G C T +Y
Sbjct: 1496 SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVN-GLCVNTPGRY 1554
Query: 1082 RCECPSGW----TGLYC---------------DVPSVSCEVAAQRQGVDVAR---LCQHG 1119
C CP + TG+ C S+SC GV V+R C G
Sbjct: 1555 ECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEI---GVGVSRSSCCCSLG 1611
Query: 1120 -------GLCVDAGNTHHCRCQAGYTG------SYCEDLVDECS--PSPCQNGATCTDYL 1164
C +T + G G + + +DEC P CQ G C +
Sbjct: 1612 KAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQ-GGNCINTF 1670
Query: 1165 GGYSCKCVAGYH---GVNCSEEIDECLSHPCQNG-GTCLDLPNTYKCSCPRGTQGVHCEI 1220
G + C+C GY+ E+IDEC +HP G GTC + Y C CP V+
Sbjct: 1671 GSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGH 1730
Query: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGER---CEGDVNECLSNPCD 1277
N D S + +N TC +++ P V +R C +V + + PC+
Sbjct: 1731 NCMDMRK-----SFCYRSYNGTTCENEL--------PFNVTKRMCCCTYNVGKAWNKPCE 1777
Query: 1278 ARGTQNCVQRVNDFHCECR-------AGHTGRRCESVINGCKGKP--CKNGGTCAVASNT 1328
T DF C HTG+ + I+ CK P C NG V N
Sbjct: 1778 PCPTPGTA----DFKTICGNIPGFTFDIHTGKAVD--IDECKEIPGICANG----VCINQ 1827
Query: 1329 ARGFICKCPAGFEG----ATCEN-DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC 1383
F C+CP GF CE+ D + G C CI+ P S C C F
Sbjct: 1828 IGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGF----- 1882
Query: 1384 QFPASSPCLGGNPCY------NQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG 1437
+ + C+ N C + G C S Y+C+C F A
Sbjct: 1883 KLSPNGACVDRNECLEIPNVCSHGLCVDLQGS--YQCICHNGFK--------------AS 1926
Query: 1438 RDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCW 1497
+D + + CE C GN C ++ C G + ND C +C
Sbjct: 1927 QDQTMCMDVDECERHPC----GNGTCKNTVGSYNCLCYPGFELTHNND----CLDIDECS 1978
Query: 1498 KYFS----DGHCDSQCNSAGCL--------------FDGFDCQRAEGQCNP 1530
+F +G C ++ S CL D +C G C+P
Sbjct: 1979 SFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSP 2029
Score = 441 bits (1134), Expect = e-123
Identities = 430/1518 (28%), Positives = 602/1518 (39%), Gaps = 397/1518 (26%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPR----CQDPNPC-LSTPCKNAGTCHVVD 78
C + C +GG+C G C+C F+ C D N C L++ G C +
Sbjct: 1287 CENNPDIC-DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE--N 1343
Query: 79 RRGVADYACSCALGFS---GPLCLTPLDNACL-TNPCRNGGTCDLLTLTEYKCRCPPGWS 134
+G + C C LG+S G T +D + + C +C L +KC C GW
Sbjct: 1344 TKG--SFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC-LNIPGSFKCSCREGWI 1400
Query: 135 GKS--CQQADPCAS--NPCANGGQCLPFEASYICHCPPSFHGP--TCRQDVNECGQKPGL 188
G C D C++ + C+ QC+ SY C C F G TC DV+EC + L
Sbjct: 1401 GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTC-SDVDECAENINL 1459
Query: 189 CRHG----------------------------------------GTCHNEVGSYRCVC-- 206
C +G GTC+N G + C+C
Sbjct: 1460 CENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDD 1519
Query: 207 --RATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF----TGQNCEEN-ID 259
TG NC P C NG G +EC C P F TG C +N +
Sbjct: 1520 GYELDRTGGNCTDIDECADPINCVNGLCVNTPG--RYECNCPPDFQLNPTGVGCVDNRVG 1577
Query: 260 DCPGNNCKNGGACVD-------GVNTYNC-------------RCPPEWTGQYCT------ 293
+C G + GV+ +C CPP + +Y T
Sbjct: 1578 NCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGE 1637
Query: 294 -----------EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW-TGEDCS--ENIDDC 339
ED+DECQ +P CQ GG C NT G + C C G+ ED E+ID+C
Sbjct: 1638 GFRPNPITIILEDIDECQELPGLCQ-GGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC 1696
Query: 340 AS--AACFHGATCHDRVASFYCECP---------------------HGRTGLLCHLND-- 374
+ C G TC++ + ++ C CP G C N+
Sbjct: 1697 FAHPGVCGPG-TCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCE-NELP 1754
Query: 375 -------ACISNPCNEGSN--CDTNPVNG----KAICTCPSGYT-----GPACSQDVDEC 416
C + + N C+ P G K IC G+T G A D+DEC
Sbjct: 1755 FNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAV--DIDEC 1812
Query: 417 SLGANPCEHAGKCINTLGSFECQCLQGYTGPR----CEIDVNECVS--NPCQNDATCLDQ 470
C + G CIN +GSF C+C G++ CE D++EC + N CQ +A C++
Sbjct: 1813 KEIPGICAN-GVCINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINS 1870
Query: 471 IGEFQCICMPGYE---GVHCEVNTDECASSP--CLHNGRCLDKINEFQCECPTGFTGHLC 525
G ++C C G++ C V+ +EC P C H G C+D +QC C GF
Sbjct: 1871 PGSYRCECAAGFKLSPNGAC-VDRNECLEIPNVCSH-GLCVDLQGSYQCICHNGFKASQD 1928
Query: 526 Q---YDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE--VDIDECDP---DPCHY 577
Q DVDEC PC NG C + +Y C+C G+ TH +DIDEC C
Sbjct: 1929 QTMCMDVDECERHPCGNGT-CKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN 1987
Query: 578 GSCKDGVATFTCLCRPGYT----GHHCETNINECSSQPCRHG-GTCQDRDNAYLCFCLKG 632
G C + + +F CLC GY G +C + NEC + P GTCQ+ + ++ C C G
Sbjct: 1988 GRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLEGSFRCICPPG 2046
Query: 633 --TTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYT------------GSMCN 676
NC I++++C P C G+C + G++C C PG+ S C
Sbjct: 2047 YEVKSENC-IDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF 2105
Query: 677 INIDE-----------------CAGNPCHN-GGTCE----DGINGFTCRCPEGYHDPTCL 714
N + C+ P G CE D F CP G+ L
Sbjct: 2106 TNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSL 2165
Query: 715 ----SEVNECNSNP--CVHGACRDSLNGYKCDCDPGWS----GTNCDINNNECE-SNPCV 763
+VNEC +P C +G C ++ ++C+C G++ G C ++ +EC NPC
Sbjct: 2166 HDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPCG 2224
Query: 764 NGGTCKDMTSGYVCTCREGFS-GP--NCQTNINECASNPCLNQGTCIDDVAGYKCNCLLP 820
NG TC ++ + C C EGF GP NC+ +INECA NP L C++ Y+C C +
Sbjct: 2225 NG-TCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCPIG 2282
Query: 821 YTGATCEVVLAPCAPSPCRNGGECRQS-EDYES-----------FSCVCPTGW----QGQ 864
Y + + C++ EC + D ES F C+CP G G+
Sbjct: 2283 YALREDQKM--------CKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGE 2334
Query: 865 TCEVDINECVLSP----------------------------------------------- 877
C VD NEC P
Sbjct: 2335 GC-VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQT 2393
Query: 878 -CRHGASCQNTHGGYRCHCQAGYS-GRNCET------------------------DIDDC 911
C+ +S +N C C G G CE DID+C
Sbjct: 2394 ICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDEC 2453
Query: 912 R--PNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASDPCRNGANCTDCVD 965
+ PN C NG C + + + C C G+ GT C D++EC+ P C +
Sbjct: 2454 KVMPNLCTNG-QCINTMGSFRCFCKVGYTTDISGTSCI-DLDECSQSPKPCNYICKNTEG 2511
Query: 966 SYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH- 1020
SY C+CP G+ G C++ +C CV+ + FTC CPPGFT +
Sbjct: 2512 SYQCSCPRGYVLQEDGKTCKD-LDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACI 2570
Query: 1021 DVNECDSQPCLHG--GTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSPCKNGGKC 1074
D NEC SQP L G G CQ+ GS+ C C +G+ TG NC+++ + C++G C
Sbjct: 2571 DNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG--C 2628
Query: 1075 WQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG-----NTH 1129
YRC CP G+ Y Q VD C + C A ++
Sbjct: 2629 QNILGGYRCGCPQGYIQHY-----------QWNQCVDENE-CSNPNACGSASCYNTLGSY 2676
Query: 1130 HCRCQAGYT----GSYCEDLVDECSPS--PCQNGATCTDYLGGYSCKCVAGYHGVNCSEE 1183
C C +G++ S C D V+ECS S PC G C++ GGY C C GY+ V
Sbjct: 2677 KCACPSGFSFDQFSSACHD-VNECSSSKNPCNYG--CSNTEGGYLCGCPPGYYRVGQG-- 2731
Query: 1184 IDECLSHPCQNGGTCLDL 1201
C+S N G L L
Sbjct: 2732 --HCVSGMGFNKGQYLSL 2747
Score = 437 bits (1125), Expect = e-122
Identities = 457/1674 (27%), Positives = 651/1674 (38%), Gaps = 359/1674 (21%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
C+NGG C + C C ++G C P C+N G C + C+C
Sbjct: 153 CMNGGTC----ADDHCQCQKGYIGTYCGQP--VCENGCQNGGRC-------IGPNRCACV 199
Query: 91 LGFSGPL---------CLTPLDN----------------ACLTNPCRNGGTCDLLTLTEY 125
GF+GP C T ++N C T G C++
Sbjct: 200 YGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQ 259
Query: 126 KCR--CPPGWSGKSCQQADPCASNP-CANGGQCLPFEASYICHCPPSFHGPTCRQ---DV 179
CR P +CQ D C + P GG C+ S+ C CP Q D+
Sbjct: 260 PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDI 319
Query: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHT----GPNC-------------------- 215
+EC PG+C G C N VGSY CVC + G C
Sbjct: 320 DECSIIPGIC-ETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQE 378
Query: 216 -----ERPYVPCSPSPCQNGGT----CRPTGDVTHECACLPGFTGQNCEENIDDCPGNNC 266
+ C P C GT C G + C+ G + PG
Sbjct: 379 LPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTG 438
Query: 267 KNGGACVDGVNTY-------------NCRCP-------------PEWTG-QYCTEDVDEC 299
NG A N Y N P P TG + +D C
Sbjct: 439 GNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDIC 498
Query: 300 QLMPNACQNGGTCHNTHGGYNCVCVNGWTGE---DCSENIDDCASAACFHGATCHDRVAS 356
+ N C N G C T Y C C G+ + DC + +D+C S C +G C + S
Sbjct: 499 KHHANLCLN-GRCIPTVSSYRCECNMGYKQDANGDCID-VDECTSNPCTNG-DCVNTPGS 555
Query: 357 FYCECPHG----RTGLLCHLNDACISNP--CNEGSNCDTNPVNGKAICTCPSGY----TG 406
+YC+C G T C D CI N C G +T +G C C +G+ G
Sbjct: 556 YYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNT---DGSFQCICNAGFELTTDG 612
Query: 407 PACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNECVSNPCQ 462
C D DEC+ N C + G CIN GSF+C C G+ G C DV+EC +
Sbjct: 613 KNC-VDHDECTT-TNMCLN-GMCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGIC 668
Query: 463 NDATCLDQIGEFQCICMPGYE-GVHCEVNTDECASSPC---LHNGRCL----DKINEFQC 514
+ C++ G F+C C PG G+ V D S C + G C+ + + +C
Sbjct: 669 MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSEC 728
Query: 515 ECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDEC--DP 572
C G + C P KN A+ + +C+ G T DI+EC DP
Sbjct: 729 CCANPDYGF-----GEPCQPCPAKNSAE-------FHGLCSSGVGITVDGRDINECALDP 776
Query: 573 DPCHYGSCKDGVATFTCLCRPGY----TGHHCETNINEC-SSQPCRHGGTCQDRDNAYLC 627
D C G C++ ++ C C GY +G +C +I+EC ++ G C++ +Y C
Sbjct: 777 DICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYSC 835
Query: 628 FCLKG----TTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPG----YTGSMCNINI 679
C G T CE ++++C S+PC +G C + + + C C PG TG +C I
Sbjct: 836 TCPPGYVFRTETETCE-DINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLIC---I 891
Query: 680 DECAGNPCHN--GGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC----VHGACRDS 733
D G N CE ING T + C + + +PC + AC
Sbjct: 892 DSLKGTCWLNIQDSRCEVNINGATLK-------SECCATLGAAWGSPCERCELDTACPRG 944
Query: 734 LNGYKCDCDPGWSGTNCDINNNECESNP--CVNGGTCKDMTSGYVCTCREGFSGPNCQTN 791
L K G C+ + NECE P C N G C + + C C EG +
Sbjct: 945 LARIK--------GVTCE-DVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGRV 994
Query: 792 INECASNPCL---NQGTCIDDVAG-YKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
+ C ++ CI V G ++ + GA C P P +
Sbjct: 995 CLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEEC-PKP--------GT 1045
Query: 848 EDYESFSCVCPTG---------WQGQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQ 896
++YE+ +CP G G+ DINEC P C +G C+NT G ++C C
Sbjct: 1046 KEYET---LCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYG-KCRNTIGSFKCRCN 1101
Query: 897 AGYS----GRNCETDIDDCRPNPCHNG-GSCTDGINTAFCDCLPGFRGTFCE----EDIN 947
+G++ RNC TDID+CR +P G G C + + C+C G+ F DI+
Sbjct: 1102 SGFALDMEERNC-TDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDID 1160
Query: 948 ECASDP--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS-----CFNGGTCVD 1000
EC +P CR G C + S+ C CP G + D E S C N G CV+
Sbjct: 1161 ECERNPLLCR-GGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-GKCVN 1218
Query: 1001 GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGG---TCQDGCGSYRCTCPQGYT----G 1053
I ++ C C PG+ + + + D ++GG C + GSY C+C +GY G
Sbjct: 1219 MIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDG 1278
Query: 1054 PNCQNLVHWCDSSP-CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112
+C + + C+++P +GG+C +YRC C G+ + S+ + D+
Sbjct: 1279 RSCAD-IDECENNPDICDGGQCTNIPGEYRCLCYDGF------MASMDMKTCIDVNECDL 1331
Query: 1113 -ARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDEC--SPSPCQNGATCTDYLG 1165
+ +C G C + + C CQ GY+ + C D VDEC C A+C + G
Sbjct: 1332 NSNICMFGE-CENTKGSFICHCQLGYSVKKGTTGCTD-VDECEIGAHNCDMHASCLNIPG 1389
Query: 1166 GYSCKCVAGY--HGVNCSEEIDECL--SHPCQNGGTCLDLPNTYKCSCPRG--TQGVHCE 1219
+ C C G+ +G+ C ++DEC +H C C++ P +Y+C+C G G C
Sbjct: 1390 SFKCSCREGWIGNGIKCI-DLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCS 1448
Query: 1220 INVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV---GERCEGDVNECLSNPC 1276
+VD+C + + NG C++ G Y C C GF R D++EC
Sbjct: 1449 -DVDEC-------AENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI 1500
Query: 1277 DARGTQNCVQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKNGGTCAVASNTARGF 1332
GT C FHC C G+ TG C + C NG + NT +
Sbjct: 1501 CVFGT--CNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNG----LCVNTPGRY 1554
Query: 1333 ICKCPAGFE----GATC-ENDARTC---------GSLRCLNGGTCISGPRSPTCLCLGPF 1378
C CP F+ G C +N C GSL C N + RS C LG
Sbjct: 1555 ECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSC-NTEIGVGVSRSSCCCSLGK- 1612
Query: 1379 TGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGR 1438
GNPC TC P + + +Y LCP GG R
Sbjct: 1613 -------------AWGNPC---ETCPPVNSTEYY-TLCP---------------GGEGFR 1640
Query: 1439 DIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQ 1492
P +I E ++ ECQE G +C GG+C F C Q
Sbjct: 1641 PNPITIILE--DIDECQELPG--LC-----------QGGNCINTFGSFQCECPQ 1679
Score = 292 bits (748), Expect = 3e-78
Identities = 355/1335 (26%), Positives = 501/1335 (37%), Gaps = 288/1335 (21%)
Query: 350 CHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
C R S YC CP +T + CI C ++C + +CTC SG C
Sbjct: 89 CGSRFHS-YC-CPGWKT---LPGGNQCIVPICR--NSCGDGFCSRPNMCTCSSGQISSTC 141
Query: 410 -SQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL 468
S+ + +CS+ C + G C + CQC +GY G C V E N CQN C
Sbjct: 142 GSKSIQQCSVR---CMNGGTCADD----HCQCQKGYIGTYCGQPVCE---NGCQNGGRC- 190
Query: 469 DQIGEFQCICMPGYEGVHCEVNTDECASSPC---LHNGRCLDKINEFQCE---------- 515
IG +C C+ G+ G CE + + PC ++N C ++ C
Sbjct: 191 --IGPNRCACVYGFTGPQCE---RDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGR 245
Query: 516 ---------------CPTGFTGHL----CQYDVDECASTP--CKNGAKCLDGPNTYTCVC 554
C GF ++ CQ DVDEC + P C+ G C++ ++ C C
Sbjct: 246 AWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGG-NCINTVGSFECRC 303
Query: 555 TEGY----TGTHCEVDIDECD--PDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECS 608
G+ T CE DIDEC P C G C + V ++ C+C GY T+ + C
Sbjct: 304 PAGHKQSETTQKCE-DIDECSIIPGICETGECSNTVGSYFCVCPRGYV---TSTDGSRCI 359
Query: 609 SQP---CRHG---GTCQD----RDNAYLCFCLKG------TTGPNCEINLDDCASSPCDS 652
Q C G G C R C C G T C + + C
Sbjct: 360 DQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMD 419
Query: 653 GTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCE---DGINGFT-----CRC 704
G + I G PG TG N GN GGT G NGF+
Sbjct: 420 GLPMGGIPG-SAGSRPGGTGG--NGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGV 476
Query: 705 PEGYHDP--TCLSEVNEC------NSNPCVHGACRDSLNGYKCDCDPGW-SGTNCD-INN 754
G P T L+ +N+ ++N C++G C +++ Y+C+C+ G+ N D I+
Sbjct: 477 GAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDV 536
Query: 755 NECESNPCVNGGTCKDMTSGYVCTCREGFS-GPNCQT--NINECASNPCL-NQGTCIDDV 810
+EC SNPC N G C + Y C C GF P Q +I+EC N L G C++
Sbjct: 537 DECTSNPCTN-GDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTD 595
Query: 811 AGYKCNC----LLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW----Q 862
++C C L G C V C + G C + SF C+C G+
Sbjct: 596 GSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINEDG--SFKCICKPGFVLAPN 652
Query: 863 GQTCEVDINECVLSPCRHGASCQNTHGGYRCHC----QAGYSGRNC-------------- 904
G+ C D++EC C N+ G +RC C G GR C
Sbjct: 653 GRYC-TDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
Query: 905 -----------ETDIDDCRPNPCHNGGS----CTDGINTAFCD-CLPGFRGTFCEEDINE 948
T + C NP + G C + F C G T DINE
Sbjct: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINE 771
Query: 949 CASDP--CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGI 1002
CA DP C NG C + SY C C +G+ SG +C + + G C +
Sbjct: 772 CALDPDICANGI-CENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTP 830
Query: 1003 NSFTCLCPPGF---TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQG----YTGPN 1055
S++C CPPG+ T + D+NEC+S PC++ G C++ GS+ C C G TG
Sbjct: 831 GSYSCTCPPGYVFRTETETCEDINECESNPCVN-GACRNNLGSFNCECSPGSKLSSTGLI 889
Query: 1056 C-QNLVHWC------------------DSSPCKNGGKCWQTHTQYRCE----CPSGWTGL 1092
C +L C S C G W + + RCE CP G
Sbjct: 890 CIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCE-RCELDTACPRG---- 944
Query: 1093 YCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDL--- 1145
+ V+CE + +V G CV++ + HC C G TG C D+
Sbjct: 945 LARIKGVTCEDVNE---CEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
Query: 1146 -------VDEC---SPSPCQNGATCTDYLGGYSCKCV-----------------AGY--- 1175
DEC P + A C + +C AG+
Sbjct: 1002 QCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANR 1061
Query: 1176 ----HGVNCSEEIDECLSHPCQ-NGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVD 1230
G ++I+EC + P G C + ++KC C G ++ +C +D
Sbjct: 1062 GDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRC---NSGFALDMEERNCT-DID 1117
Query: 1231 PVSRSPKCFNNGTCVDQVGGYSCTC----PPGFVGERCEGDVNECLSNPCDARGTQNCVQ 1286
SP +G CV+ G + C C GF+ + D++EC NP RG CV
Sbjct: 1118 ECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRG-GTCVN 1176
Query: 1287 RVNDFHCECRAGH--TGRRCESV-INGC--KGKPCKNGGTCAVASNTARGFICKCPAGFE 1341
F C+C GH + R + V IN C C+N G C N + C C G++
Sbjct: 1177 TEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-GKCV---NMIGTYQCSCNPGYQ 1232
Query: 1342 GATCENDARTCGSLRCLNGG---TCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCY 1398
+NGG C + S C C + P C + C
Sbjct: 1233 ATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGY----ALMPDGRSCADIDECE 1288
Query: 1399 NQ------GTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPP-PLIEEACEL 1451
N G C T+ YRCLC ++G + S D+ L C
Sbjct: 1289 NNPDICDGGQC--TNIPGEYRCLC---YDGFMA-----SMDMKTCIDVNECDLNSNICMF 1338
Query: 1452 PECQEDAGNKVCSLQ 1466
EC+ G+ +C Q
Sbjct: 1339 GECENTKGSFICHCQ 1353
Score = 130 bits (328), Expect = 1e-29
Identities = 116/369 (31%), Positives = 157/369 (42%), Gaps = 63/369 (17%)
Query: 172 GPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGG 231
G V GQ+ L R C + SY C T G N + VP + C +G
Sbjct: 67 GAAVASRVRRRGQQDVL-RGPNVCGSRFHSYCCPGWKTLPGGN--QCIVPICRNSCGDGF 123
Query: 232 TCRPTGDVTHECACLPGFTGQNC-EENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQ 290
RP + C C G C ++I C C NGG C D +C+C + G
Sbjct: 124 CSRP-----NMCTCSSGQISSTCGSKSIQQC-SVRCMNGGTCADD----HCQCQKGYIGT 173
Query: 291 YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC 350
YC + V E N CQNGG C G C CV G+TG C + + C
Sbjct: 174 YCGQPVCE-----NGCQNGGRCI---GPNRCACVYGFTGPQCERD---------YRTGPC 216
Query: 351 HDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY-----T 405
+V + C+ TG++C C + G C+ P + C G+ T
Sbjct: 217 FTQVNNQMCQGQ--LTGIVCTKTLCCATIGRAWGHPCEMCPAQPQP---CRRGFIPNIRT 271
Query: 406 GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNECVSNP- 460
G AC QDVDEC C+ G CINT+GSFEC+C G+ T +CE D++EC P
Sbjct: 272 G-AC-QDVDECQAIPGICQ-GGNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPG 327
Query: 461 -CQNDATCLDQIGEFQCICMPGY----EGVHC-EVNTDECASSPCLHNGRCLD----KIN 510
C+ C + +G + C+C GY +G C + T C S L NGRC ++
Sbjct: 328 ICET-GECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG--LVNGRCAQELPGRMT 384
Query: 511 EFQCECPTG 519
+ QC C G
Sbjct: 385 KMQCCCEPG 393
Score = 122 bits (306), Expect = 5e-27
Identities = 169/672 (25%), Positives = 231/672 (34%), Gaps = 134/672 (19%)
Query: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC 992
C PG++ N+C CRN C CTC +G C + + C
Sbjct: 97 CCPGWKTL---PGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRC 153
Query: 993 FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT 1052
NGGTC D C C G+ G+YC V E C +GG C G RC C G+T
Sbjct: 154 MNGGTCADD----HCQCQKGYIGTYCGQPVCE---NGCQNGGRC---IGPNRCACVYGFT 203
Query: 1053 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112
GP C+ + PC Q + Q C TG+ C ++ C + G
Sbjct: 204 GPQCERDYR---TGPCFT-----QVNNQM---CQGQLTGIVC-TKTLCCATIGRAWG-HP 250
Query: 1113 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSCK 1170
+C G + R A C+D VDEC P CQ G C + +G + C+
Sbjct: 251 CEMCPAQPQPCRRGFIPNIRTGA------CQD-VDECQAIPGICQ-GGNCINTVGSFECR 302
Query: 1171 CVAGYHGVNCS---EEIDECLSHP--CQNGGTCLDLPNTYKCSCPRG----TQGVHCEIN 1221
C AG+ + E+IDEC P C+ G C + +Y C CPRG T G C
Sbjct: 303 CPAGHKQSETTQKCEDIDECSIIPGICET-GECSNTVGSYFCVCPRGYVTSTDGSRC--- 358
Query: 1222 VDDCNPPVDPVSRSPKCFN---NGTCVDQVGG----YSCTCPPGFVGERCEGDVNECLSN 1274
+D R+ CF+ NG C ++ G C C PG RC G +
Sbjct: 359 ID---------QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG----RCWG--IGTIPE 403
Query: 1275 PCDARGTQNCVQRVND--------FHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVAS 1326
C RG++ + D R G TG G GGT +
Sbjct: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGG--NGFAPSGNGNGYGPGGTGFIPI 461
Query: 1327 NTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCL---CLGPFTGPEC 1383
GF G G L LN I + CL C+ + C
Sbjct: 462 PGGNGF--SPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRC 519
Query: 1384 QF------PASSPCLG-----GNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSF 1432
+ A+ C+ NPC N G C T S Y C C A F
Sbjct: 520 ECNMGYKQDANGDCIDVDECTSNPCTN-GDCVNTPGS--YYCKCHAGFQ----------- 565
Query: 1433 GGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGD----CSLNF--NDP 1486
P + ++ EC ++ + C N C G C+ F
Sbjct: 566 --------RTPTKQACIDIDECIQN------GVLCKNGRCVNTDGSFQCICNAGFELTTD 611
Query: 1487 WKNCTQSLQC--WKYFSDGHCDSQCNSAGCLF-DGFDCQRAEGQCNPLYDQYCKDHFSDG 1543
KNC +C +G C ++ S C+ GF C + + +G
Sbjct: 612 GKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNG 671
Query: 1544 HCDQGCNSAECE 1555
HC S C+
Sbjct: 672 HCINSEGSFRCD 683
Score = 66.6 bits (161), Expect = 3e-10
Identities = 57/212 (26%), Positives = 77/212 (36%), Gaps = 34/212 (16%)
Query: 20 RGPRCSQPGETCLNGGKCEAAN-----------GTEACVCGGAFV--GPRCQDPNPCLST 66
RG + G+TC + +C+ G C C F C D N C S
Sbjct: 2519 RGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQ 2578
Query: 67 P--CKNAGTCHVVDRRGVADYACSCALGFS---GPLCLTPLDNACLTNPCRNGGTCDLLT 121
P C G C + ++C C GFS L +D + C++G C +
Sbjct: 2579 PSLCGAKGIC----QNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG--CQNI- 2631
Query: 122 LTEYKCRCPPG----WSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSF---HGPT 174
L Y+C CP G + C + C++ C SY C CP F +
Sbjct: 2632 LGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSS 2691
Query: 175 CRQDVNECGQKPGLCRHGGTCHNEVGSYRCVC 206
DVNEC C +G C N G Y C C
Sbjct: 2692 ACHDVNECSSSKNPCNYG--CSNTEGGYLCGC 2721
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 501 bits (1289), Expect = e-141
Identities = 242/692 (34%), Positives = 351/692 (50%), Gaps = 55/692 (7%)
Query: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPC 499
C+ G+ G C+ V + N T + C C G++G C DEC P
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGE-----CRCSYGWQGRFC----DECVPYPG 281
Query: 500 LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAST-PCKNGAKCLDG-PNTYTCVCTEG 557
+G C++ +QC C T + G LC D++ C S PC NG C++ P+ Y C C +G
Sbjct: 282 CVHGSCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDG 338
Query: 558 YTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGG 616
Y+G +CE C +PC + GSC + + F C C G++G C +I+EC+S PC GG
Sbjct: 339 YSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGG 398
Query: 617 TCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMC 675
TC D+ + + C C + G C+++ ++C PC ++ +C + I GY C C PG+ G C
Sbjct: 399 TCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINC 458
Query: 676 NINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSL 734
+IN+++C G C +GGTC+D +NG+ C CP G+ C E +EC S+PC G C D
Sbjct: 459 HINVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLA 517
Query: 735 NGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE 794
+G+ C C G+SG C+++ + CE +PC NG C ++ Y C C + F G NC
Sbjct: 518 DGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREP 577
Query: 795 C-----------------------ASNPCLNQGTCIDDVAG-YKCNCLLPYTGATCEVVL 830
C AS C G C+ G + C C +TG C +
Sbjct: 578 CPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI 637
Query: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGG 890
C PCRNGG C ++ ++F C CP+GW+G+ C+ + N+C+ PC C +
Sbjct: 638 DDCLGQPCRNGGTC--IDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVND 695
Query: 891 YRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINE-C 949
+ C C G+ G+ C + C C NGG+C D +T C C PG++G+ C N C
Sbjct: 696 FYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSC 755
Query: 950 ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLC 1009
+PC NG C S++C C G+ G C +NT DC C+NGG CVDG+N F C C
Sbjct: 756 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCEC 815
Query: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVH-----WCD 1064
PGF G C+ +++EC S PC +G TC D YRC+CP G GP CQ ++ W
Sbjct: 816 APGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSR 875
Query: 1065 SSPCKNGGKCWQTHTQYRC-----ECPSGWTG 1091
+P +G + RC +C W G
Sbjct: 876 GTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCG 907
Score = 498 bits (1281), Expect = e-140
Identities = 264/770 (34%), Positives = 365/770 (47%), Gaps = 108/770 (14%)
Query: 233 CRPTGDVT--HEC------ACLPGFTGQNCEENIDDCPGNNCKNGGACVDG--------- 275
CRP D + C AC+ G+ G+ C+E + G N +GG V G
Sbjct: 211 CRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCK-QGCNLLHGGCTVPGECRCSYGWQ 269
Query: 276 ------------------VNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTH- 316
V + C C W G C +D++ C + C NGGTC N
Sbjct: 270 GRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCG-SHHPCTNGGTCINAEP 328
Query: 317 GGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DA 375
Y C C +G++G +C + C S C +G +CH+ + F C CP G +G C L+ D
Sbjct: 329 DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE 388
Query: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435
C SNPC G C + V+G C CP + G C D +EC PC +A C N +G
Sbjct: 389 CASNPCAAGGTC-VDQVDGFE-CICPEQWVGATCQLDANECE--GKPCLNAFSCKNLIGG 444
Query: 436 FECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECA 495
+ C C+ G+ G C I+VN+C CQ+ TC D + +QC+C G+ G HCE+ DECA
Sbjct: 445 YYCDCIPGWKGINCHINVNDC-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECA 503
Query: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT 555
SSPC G C D + F C CP GF+G LC+ DVD C +PC+NGA+C + Y C C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACP 563
Query: 556 EGYTGTHCEVDIDEC-------------DPDPCHYGSCKDGV------------ATFTCL 590
+ + G +C V + C D P G+ GV F+C+
Sbjct: 564 DDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCI 623
Query: 591 CRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC 650
C G+TG +C NI++C QPCR+GGTC D +A+ CFC G G C+ N +DC PC
Sbjct: 624 CDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPC 683
Query: 651 DS-GTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYH 709
S G C D ++ + CAC+ G+ G C+ +C C NGGTC D + F C CP G+
Sbjct: 684 HSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWK 743
Query: 710 DPTC-LSEVNECNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGT 767
TC +++ + C NPCV+ G C S + C C GW G C N N+C PC NGG
Sbjct: 744 GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 803
Query: 768 CKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCE 827
C D + + C C GF+GP+C+ NI+EC S+PC TC+D++ GY+C+C G C+
Sbjct: 804 CVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 863
Query: 828 VVLA--------------------PCAPSPCRNGGE-----------CRQSEDYESFSCV 856
V+ C C +G C + E+ S
Sbjct: 864 EVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQ 923
Query: 857 CPTGWQGQTC-EVDINECVLSPCRHGASC-QNTHGGYRCHCQAGYSGRNC 904
CP GQ C E +C+ PC C C ++G+ NC
Sbjct: 924 CPL---GQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNC 970
Score = 497 bits (1279), Expect = e-140
Identities = 266/814 (32%), Positives = 377/814 (46%), Gaps = 104/814 (12%)
Query: 554 CTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTC------LCRPGYTGHHCETNINEC 607
C E Y C C P +G +TC C G+ G C+ +
Sbjct: 198 CDENYYSATCN---KFCRPRNDFFGH-------YTCDQYGNKACMDGWMGKECKEAV--- 244
Query: 608 SSQPCR--HGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSP-CDSGTCLDKIDGYEC 664
Q C HGG + C C G G C D+C P C G+C ++ ++C
Sbjct: 245 CKQGCNLLHGGCTVPGE----CRCSYGWQGRFC----DECVPYPGCVHGSC---VEPWQC 293
Query: 665 ACEPGYTGSMCNINIDECAGN-PCHNGGTCEDGI-NGFTCRCPEGYHDPTCLSEVNECNS 722
CE + G +C+ +++ C + PC NGGTC + + + C CP+GY C + C S
Sbjct: 294 NCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS 353
Query: 723 NPCVHG-ACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCRE 781
NPC +G +C + +G++C C GWSG C ++ +EC SNPC GGTC D G+ C C E
Sbjct: 354 NPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPE 413
Query: 782 GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNG 841
+ G CQ + NEC PCLN +C + + GY C+C+ + G C + + C C++G
Sbjct: 414 QWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCR-GQCQHG 472
Query: 842 GECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSG 901
G C+ + + CVCP G+ G+ CE++ +EC SPC G C++ G+ CHC G+SG
Sbjct: 473 GTCKDLVN--GYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSG 530
Query: 902 RNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCT 961
CE D+D C P+PC NG C + +C C F G C C CR C
Sbjct: 531 PLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCG 590
Query: 962 D--------------------CVD----SYTCTCPAGFSGIHCENNTPDCTESSCFNGGT 997
CV +++C C +GF+G +C N DC C NGGT
Sbjct: 591 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 650
Query: 998 CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
C+D +++F C CP G+ G C + N+C PC G C D + C C G+ G C
Sbjct: 651 CIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH 710
Query: 1058 NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVP-SVSCEVAAQRQGVDVARLC 1116
+ CD+ C NGG C+ + +RC CP GW G C V + SC + C
Sbjct: 711 SREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSC----------LPNPC 760
Query: 1117 QHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH 1176
+GG CV +G + C C+ G+ G C ++C+P PC NG C D + + C+C G+
Sbjct: 761 VNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFA 820
Query: 1177 GVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVD---DC---NPPVD 1230
G +C IDEC S PC G TC+D N Y+CSCP G G C+ + C P
Sbjct: 821 GPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFP 880
Query: 1231 PVSRSPKCFNNGTCVD-------------------QVGGYSCTCPPGFVGERC-EGDVNE 1270
S + N+ C+D Q S CP +G+RC E +
Sbjct: 881 HGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCP---LGQRCLEKAPGQ 937
Query: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRC 1304
CL PC+A G + + C R+GH C
Sbjct: 938 CLRPPCEAWG-ECGAEEPPSTPCLPRSGHLDNNC 970
Score = 496 bits (1278), Expect = e-140
Identities = 263/744 (35%), Positives = 361/744 (48%), Gaps = 109/744 (14%)
Query: 531 ECASTPCKNGAKCLDGPNTYT--CVCTEGYTGTHCEVDIDECDPDP-CHYGSCKDGVATF 587
EC CK G L G T C C+ G+ G C DEC P P C +GSC V +
Sbjct: 239 ECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGCVHGSC---VEPW 291
Query: 588 TCLCRPGYTGHHCETNINECSSQ-PCRHGGTCQDRD-NAYLCFCLKGTTGPNCEINLDDC 645
C C + G C+ ++N C S PC +GGTC + + + Y C C G +G NCE C
Sbjct: 292 QCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHAC 351
Query: 646 ASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRC 704
S+PC + G+C + G+EC C G++G C ++IDECA NPC GGTC D ++GF C C
Sbjct: 352 TSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECIC 411
Query: 705 PEGYHDPTCLSEVNECNSNPCVHG-ACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV 763
PE + TC + NEC PC++ +C++ + GY CDC PGW G NC IN N+C C
Sbjct: 412 PEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQ-CQ 470
Query: 764 NGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTG 823
+GGTCKD+ +GY C C GF G +C+ +ECAS+PC + G C D G+ C+C ++G
Sbjct: 471 HGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSG 530
Query: 824 ATCEVVLAPCAPSPCRN--------------------------------GGECRQ----- 846
CEV + C PSPCRN GG CR
Sbjct: 531 PLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCG 590
Query: 847 -----------------------SEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGAS 883
S+ +FSC+C +G+ G C +I++C+ PCR+G +
Sbjct: 591 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 650
Query: 884 CQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCE 943
C + +RC C +G+ G C+T+ +DC P+PCH+ G C D +N +C C G++G C
Sbjct: 651 CIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH 710
Query: 944 EDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCE-NNTPDCTESSCFNGGTCVDGI 1002
+C + C NG C D D++ C CP G+ G C C + C NGGTCV
Sbjct: 711 SREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG 770
Query: 1003 NSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHW 1062
SF+C+C G+ G C H+ N+C+ PC +GG C DG +RC C G+ GP+C+ +
Sbjct: 771 ASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDE 830
Query: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLC------ 1116
C SSPC G C YRC CP G G C ++ + R C
Sbjct: 831 CQSSPCAYGATCVDEINGYRCSCPPGRAGPRC------------QEVIGFGRSCWSRGTP 878
Query: 1117 -QHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
HG V+ N+ CRC G C + C PC S +C G
Sbjct: 879 FPHGSSWVEDCNS--CRCLDGRRD--CSKV--WCGWKPC----LLAGQPEALSAQCPLGQ 928
Query: 1176 HGVNCSEEI-DECLSHPCQNGGTC 1198
C E+ +CL PC+ G C
Sbjct: 929 ---RCLEKAPGQCLRPPCEAWGEC 949
Score = 481 bits (1238), Expect = e-135
Identities = 263/756 (34%), Positives = 358/756 (47%), Gaps = 79/756 (10%)
Query: 106 CLTNPCRNGGTCDLL---TLTEYKCRCPPGWSGKSCQQADPCASNP-CANGGQCLPFEAS 161
C C+ G C+LL +CRC GW G+ C D C P C +G P++
Sbjct: 240 CKEAVCKQG--CNLLHGGCTVPGECRCSYGWQGRFC---DECVPYPGCVHGSCVEPWQ-- 292
Query: 162 YICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHN-EVGSYRCVCRATHTGPNCERPYV 220
C+C ++ G C +D+N CG C +GGTC N E YRC C ++G NCE+
Sbjct: 293 --CNCETNWGGLLCDKDLNYCGSHHP-CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEH 349
Query: 221 PCSPSPCQNGGTCR--PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT 278
C+ +PC NGG+C P+G EC C G++G C +ID+C N C GG CVD V+
Sbjct: 350 ACTSNPCANGGSCHEVPSG---FECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDG 406
Query: 279 YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDD 338
+ C CP +W G C D +EC+ P C N +C N GGY C C+ GW G +C N++D
Sbjct: 407 FECICPEQWVGATCQLDANECEGKP--CLNAFSCKNLIGGYYCDCIPGWKGINCHINVND 464
Query: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHL-NDACISNPCNEGSNCDTNPVNGKAI 397
C C HG TC D V + C CP G G C L D C S+PC+ G C+ +
Sbjct: 465 C-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCE--DLADGFH 521
Query: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC- 456
C CP G++GP C DVD C +PC + +C N G + C C + G C + C
Sbjct: 522 CHCPQGFSGPLCEVDVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCP 579
Query: 457 -----VSNPCQNDA-----------------TCLDQI-GEFQCICMPGYEGVHCEVNTDE 493
V + C +DA C+ Q G F CIC G+ G +C N D+
Sbjct: 580 GGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDD 639
Query: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCV 553
C PC + G C+D+++ F+C CP+G+ G LC + ++C PC + +C D N + C
Sbjct: 640 CLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCA 699
Query: 554 CTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNIN-ECSSQP 611
C +G+ G C +CD C + G+C D TF C C PG+ G C N C P
Sbjct: 700 CDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP 759
Query: 612 CRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGY 670
C +GGTC ++ C C G G C N +DC PC + G C+D ++ + C C PG+
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Query: 671 TGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEV---NEC--NSNPC 725
G C INIDEC +PC G TC D ING+ C CP G P C + C P
Sbjct: 820 AGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPF 879
Query: 726 VHGAC-RDSLNGYKC-----DCDPGWSGTNCDI--NNNECESNPCVNGGTCKDMTSGYVC 777
HG+ + N +C DC W G + E S C G C + G
Sbjct: 880 PHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCL 939
Query: 778 TCREGFSGPNCQT----NINECASNPCLNQGTCIDD 809
P C+ E S PCL + +D+
Sbjct: 940 R-------PPCEAWGECGAEEPPSTPCLPRSGHLDN 968
Score = 479 bits (1232), Expect = e-134
Identities = 255/772 (33%), Positives = 360/772 (46%), Gaps = 66/772 (8%)
Query: 129 CPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGL 188
C GW GK C++A +GG +P E C C + G C +EC PG
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGE----CRCSYGWQGRFC----DECVPYPG- 281
Query: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC-SPSPCQNGGTCRPTGDVTHECACLP 247
C HG V ++C C G C++ C S PC NGGTC + C C
Sbjct: 282 CVHGSC----VEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPD 337
Query: 248 GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
G++G+NCE+ C N C NGG+C + + + C CP W+G C D+DEC N C
Sbjct: 338 GYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDEC--ASNPCA 395
Query: 308 NGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTG 367
GGTC + G+ C+C W G C + ++C C + +C + + +YC+C G G
Sbjct: 396 AGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKG 455
Query: 368 LLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAG 427
+ CH+N C G C + VNG C CP G+ G C + DEC+ ++PC G
Sbjct: 456 INCHINVNDCRGQCQHGGTC-KDLVNGYQ-CVCPRGFGGRHCELERDECA--SSPCHSGG 511
Query: 428 KCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHC 487
C + F C C QG++GP CE+DV+ C +PC+N A C + G++ C C + G +C
Sbjct: 512 LCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNC 571
Query: 488 EVNTDEC-----------------------ASSPCLHNGRCLDKI-NEFQCECPTGFTGH 523
V + C AS C +GRC+ + F C C +GFTG
Sbjct: 572 SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGT 631
Query: 524 LCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCH-YGSCKD 582
C ++D+C PC+NG C+D + + C C G+ G C+ + ++C PDPCH G C D
Sbjct: 632 YCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 583 GVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI-N 641
V F C C G+ G C + +C + C +GGTC D + + C C G G C +
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 642 LDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF 700
C +PC + GTC+ + C C G+ G C N ++C PC+NGG C DG+N F
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811
Query: 701 TCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECES 759
C C G+ P C ++EC S+PC +GA C D +NGY+C C PG +G C S
Sbjct: 812 RCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRS 871
Query: 760 NPCVNGGTCKDMTSGYV-----CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 814
C + GT S +V C C +G + C PCL G + +
Sbjct: 872 --CWSRGTPFPHGSSWVEDCNSCRCLDG----RRDCSKVWCGWKPCLLAGQ--PEALSAQ 923
Query: 815 CNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTC 866
C P E C PC GEC +E+ S C+ +G C
Sbjct: 924 C----PLGQRCLEKAPGQCLRPPCEAWGEC-GAEEPPSTPCLPRSGHLDNNC 970
Score = 478 bits (1231), Expect = e-134
Identities = 258/790 (32%), Positives = 376/790 (47%), Gaps = 72/790 (9%)
Query: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
N C++GW G++C E + G T C C +G G C D C+
Sbjct: 228 NKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGE-----CRCSYGWQGRFC---DECVPY 279
Query: 380 P-CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTL-GSFE 437
P C GS + C C + + G C +D++ C +PC + G CIN +
Sbjct: 280 PGCVHGSCVEPWQ------CNCETNWGGLLCDKDLNYCG-SHHPCTNGGTCINAEPDQYR 332
Query: 438 CQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASS 497
C C GY+G CE + C SNPC N +C + F+C C G+ G C ++ DECAS+
Sbjct: 333 CTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASN 392
Query: 498 PCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEG 557
PC G C+D+++ F+C CP + G CQ D +EC PC N C + Y C C G
Sbjct: 393 PCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPG 452
Query: 558 YTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGT 617
+ G +C +++++C H G+CKD V + C+C G+ G HCE +EC+S PC GG
Sbjct: 453 WKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGL 512
Query: 618 CQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDG-YECACEPGYTGSMCN 676
C+D + + C C +G +GP CE+++D C SPC +G ++G Y CAC + G C+
Sbjct: 513 CEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCS 572
Query: 677 INIDECAGNPCH------------NGGTCEDGING------------FTCRCPEGYHDPT 712
+ + C G C GT G+ G F+C C G+
Sbjct: 573 VPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTY 632
Query: 713 CLSEVNECNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDM 771
C +++C PC + G C D ++ ++C C GW G CD N N+C +PC + G C D+
Sbjct: 633 CHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 692
Query: 772 TSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVL- 830
+ + C C +G+ G C + +C + C N GTC D ++C C + G+TC V
Sbjct: 693 VNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKN 752
Query: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGG 890
+ C P+PC NGG C S SFSC+C GW+G+TC + N+C PC +G C +
Sbjct: 753 SSCLPNPCVNGGTCVGSG--ASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNW 810
Query: 891 YRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDI---N 947
+RC C G++G +C +ID+C+ +PC G +C D IN C C PG G C+E I
Sbjct: 811 FRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGR 870
Query: 948 ECAS--DPCRNGANCTDCVDSYTCTCPAG---FSGIHCE------NNTPDCTESSCFNGG 996
C S P +G++ + D +C C G S + C P+ + C G
Sbjct: 871 SCWSRGTPFPHGSSWVE--DCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQ 928
Query: 997 TCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL-HGGTCQDGCGSY-----RCTCPQG 1050
C++ CL PP C E S PCL G + C R PQG
Sbjct: 929 RCLEKAPG-QCLRPPCEAWGEC--GAEEPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQG 985
Query: 1051 YT-GPNCQNL 1059
T G C +
Sbjct: 986 TTVGAICSGI 995
Score = 459 bits (1181), Expect = e-128
Identities = 248/772 (32%), Positives = 365/772 (47%), Gaps = 92/772 (11%)
Query: 46 CVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNA 105
C C + G C + C+ P G+C V + C+C + G LC L+
Sbjct: 262 CRCSYGWQGRFCDE---CVPYPGCVHGSC-------VEPWQCNCETNWGGLLCDKDLNYC 311
Query: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQAD-PCASNPCANGGQCLPFEASYIC 164
+PC NGGTC +Y+C CP G+SG++C++A+ C SNPCANGG C + + C
Sbjct: 312 GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC 371
Query: 165 HCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSP 224
HCP + GPTC D++EC P C GGTC ++V + C+C G C+ C
Sbjct: 372 HCPSGWSGPTCALDIDECASNP--CAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG 429
Query: 225 SPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCP 284
PC N +C+ + C C+PG+ G NC N++DC G C++GG C D VN Y C CP
Sbjct: 430 KPCLNAFSCKNLIG-GYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDLVNGYQCVCP 487
Query: 285 PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAAC 344
+ G++C + DEC P C +GG C + G++C C G++G C ++D C + C
Sbjct: 488 RGFGGRHCELERDECASSP--CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPC 545
Query: 345 FHGATCHDRVASFYCECPH---GRT---------GLLCHLNDAC------------ISNP 380
+GA C++ +YC CP G+ G C + D C S
Sbjct: 546 RNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGV 605
Query: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC 440
C C + P G C C SG+TG C +++D+C LG PC + G CI+ + +F C C
Sbjct: 606 CGPHGRCVSQP-GGNFSCICDSGFTGTYCHENIDDC-LG-QPCRNGGTCIDEVDAFRCFC 662
Query: 441 LQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCL 500
G+ G C+ + N+C+ +PC + C D + +F C C G++G C +C + C
Sbjct: 663 PSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCS 722
Query: 501 HNGRCLDKINEFQCECPTGFTGHLCQYDVD-ECASTPCKNGAKCLDGPNTYTCVCTEGYT 559
+ G C D + F+C CP G+ G C + C PC NG C+ +++C+C +G+
Sbjct: 723 NGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE 782
Query: 560 GTHCEVDIDECDPDPCHYGS-CKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTC 618
G C + ++C+P PC+ G C DGV F C C PG+ G C NI+EC S PC +G TC
Sbjct: 783 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATC 842
Query: 619 QDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNIN 678
D N Y C C G GP C+ ++ G+ +C
Sbjct: 843 VDEINGYRCSCPPGRAGPRCQ------------------EVIGFGRSC------------ 872
Query: 679 IDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYK 738
G P +G + + N +CRC +G D S+V C PC+ ++L+ +
Sbjct: 873 --WSRGTPFPHGSSWVEDCN--SCRCLDGRRD---CSKV-WCGWKPCLLAGQPEALSA-Q 923
Query: 739 CDCDPGWSGTNC-DINNNECESNPCVNGGTC-KDMTSGYVCTCREGFSGPNC 788
C G C + +C PC G C + C R G NC
Sbjct: 924 CPL-----GQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNC 970
Score = 407 bits (1046), Expect = e-113
Identities = 252/814 (30%), Positives = 348/814 (42%), Gaps = 134/814 (16%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP-CRHGASCQNTHGGY 891
C + C+ G C C GWQG+ C+ ECV P C HG+ + +
Sbjct: 240 CKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCD----ECVPYPGCVHGSCVEP----W 291
Query: 892 RCHCQAGYSGRNCETDIDDCRPN-PCHNGGSCTDGINTAF-CDCLPGFRGTFCEEDINEC 949
+C+C+ + G C+ D++ C + PC NGG+C + + C C G+ G CE+ + C
Sbjct: 292 QCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHAC 351
Query: 950 ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLC 1009
S+PC NG +C + + C CP+G+SG C + +C + C GGTCVD ++ F C+C
Sbjct: 352 TSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECIC 411
Query: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCK 1069
P + G+ CQ D NEC+ +PCL+ +C++ G Y C C G+ G NC V+ C C+
Sbjct: 412 PEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQ-CQ 470
Query: 1070 NGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH 1129
+GG C Y+C CP G+ G +C++ C + C GGLC D +
Sbjct: 471 HGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSP----------CHSGGLCEDLADGF 520
Query: 1130 HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDEC-- 1187
HC C G++G CE VD C PSPC+NGA C + G Y C C + G NCS + C
Sbjct: 521 HCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPG 580
Query: 1188 ---------------------LSHPCQNGGTCLDLPN-TYKCSCPRGTQGVHCEINVDDC 1225
S C G C+ P + C C G G +C N+DDC
Sbjct: 581 GACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 640
Query: 1226 NPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCV 1285
C N GTC+D+V + C CP G+ GE C+ + N+CL +PC +RG C
Sbjct: 641 --------LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRG--RCY 690
Query: 1286 QRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTC--------------------AVA 1325
VNDF+C C G G+ C S C C NGGTC AVA
Sbjct: 691 DLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVA 750
Query: 1326 SNTA----------------RGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRS 1369
N++ F C C G+EG TC ++ C L C NGG C+ G
Sbjct: 751 KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNW 810
Query: 1370 PTCLCLGPFTGPECQFP----ASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
C C F GP+C+ SSPC G C E YRC CP G C
Sbjct: 811 FRCECAPGFAGPDCRINIDECQSSPCAYGATC--------VDEINGYRCSCPPGRAGPRC 862
Query: 1426 HILDYSFGGGA-GRDIPPP---LIEEACELPECQEDAGNKVCS-LQCNNHACGWDGGDCS 1480
+ FG R P P E C C + G + CS + C C G +
Sbjct: 863 QEV-IGFGRSCWSRGTPFPHGSSWVEDCNSCRCLD--GRRDCSKVWCGWKPCLLAGQPEA 919
Query: 1481 LNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHF 1540
L+ C +C + QC C G +C E P +
Sbjct: 920 LS-----AQCPLGQRCLE-----KAPGQCLRPPCEAWG-ECGAEEPPSTPCLPR------ 962
Query: 1541 SDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTL 1574
GH D C ++ +HVP+ G +
Sbjct: 963 -SGHLDNNCARLTLHFN----RDHVPQGTTVGAI 991
Score = 399 bits (1025), Expect = e-110
Identities = 209/611 (34%), Positives = 284/611 (46%), Gaps = 64/611 (10%)
Query: 844 CRQSEDYES-FSC------VCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGY----R 892
CR D+ ++C C GW G+ C+ + C+ G C HGG
Sbjct: 211 CRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAV-------CKQG--CNLLHGGCTVPGE 261
Query: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
C C G+ GR C D+C P P GSC + C+C + G C++D+N C S
Sbjct: 262 CRCSYGWQGRFC----DECVPYPGCVHGSCVEPWQ---CNCETNWGGLLCDKDLNYCGSH 314
Query: 953 -PCRNGANCTDCV-DSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCP 1010
PC NG C + D Y CTCP G+SG +CE CT + C NGG+C + + F C CP
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374
Query: 1011 PGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKN 1070
G++G C D++EC S PC GGTC D + C CP+ + G CQ + C+ PC N
Sbjct: 375 SGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLN 434
Query: 1071 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1130
C Y C+C GW G+ C + C CQHGG C D N +
Sbjct: 435 AFSCKNLIGGYYCDCIPGWKGINCHINVNDCR-----------GQCQHGGTCKDLVNGYQ 483
Query: 1131 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSH 1190
C C G+ G +CE DEC+ SPC +G C D G+ C C G+ G C ++D C
Sbjct: 484 CVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPS 543
Query: 1191 PCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDC---------------NPPVDPVSRS 1235
PC+NG C +L Y C+CP G +C + + C P + + S
Sbjct: 544 PCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAAS 603
Query: 1236 PKCFNNGTCVDQVGG-YSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCE 1294
C +G CV Q GG +SC C GF G C ++++CL PC GT C+ V+ F C
Sbjct: 604 GVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT--CIDEVDAFRCF 661
Query: 1295 CRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGS 1354
C +G G C++ N C PC + G C + F C C G++G TC + C +
Sbjct: 662 CPSGWEGELCDTNPNDCLPDPCHSRGRC---YDLVNDFYCACDDGWKGKTCHSREFQCDA 718
Query: 1355 LRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRC 1414
C NGGTC + C C + G C +S CL NPC N GTC + S + C
Sbjct: 719 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL-PNPCVNGGTCVGSGAS--FSC 775
Query: 1415 LCPAKFNGLLC 1425
+C + G C
Sbjct: 776 ICRDGWEGRTC 786
Score = 346 bits (887), Expect = 2e-94
Identities = 192/632 (30%), Positives = 276/632 (43%), Gaps = 116/632 (18%)
Query: 31 CLNGGKCE-------------------------------AANGT-------EACVCGGAF 52
C NGG C AA GT C+C +
Sbjct: 356 CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQW 415
Query: 53 VGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPC 111
VG CQ D N C PC NA +C + + Y C C G+ G C +++ C
Sbjct: 416 VGATCQLDANECEGKPCLNAFSC----KNLIGGYYCDCIPGWKGINCHINVNDC--RGQC 469
Query: 112 RNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSF 170
++GGTC L + Y+C CP G+ G+ C+ + D CAS+PC +GG C + CHCP F
Sbjct: 470 QHGGTCKDL-VNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGF 528
Query: 171 HGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQ-- 228
GP C DV+ C +P CR+G C+N G Y C C G NC P PC C+
Sbjct: 529 SGPLCEVDVDLC--EPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVI 586
Query: 229 ---------------NGGTCRPTGDVTHE------CACLPGFTGQNCEENIDDCPGNNCK 267
G C P G + C C GFTG C ENIDDC G C+
Sbjct: 587 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCR 646
Query: 268 NGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW 327
NGG C+D V+ + C CP W G+ C + ++C +P+ C + G C++ + C C +GW
Sbjct: 647 NGGTCIDEVDAFRCFCPSGWEGELCDTNPNDC--LPDPCHSRGRCYDLVNDFYCACDDGW 704
Query: 328 TGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHL--NDACISNPCNEGS 385
G+ C C + C +G TC+D +F C CP G G C + N +C+ NPC G
Sbjct: 705 KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGG 764
Query: 386 NCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT 445
C + C C G+ G C+ + ++C+ PC + G C++ + F C+C G+
Sbjct: 765 TCVGS--GASFSCICRDGWEGRTCTHNTNDCN--PLPCYNGGICVDGVNWFRCECAPGFA 820
Query: 446 GPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN--------------- 490
GP C I+++EC S+PC ATC+D+I ++C C PG G C+
Sbjct: 821 GPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFP 880
Query: 491 -----TDECASSPCLHNGRCLDKI-------------NEFQCECPTGFTGHLCQYDVDEC 532
++C S CL R K+ +CP G + +C
Sbjct: 881 HGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLG--QRCLEKAPGQC 938
Query: 533 ASTPCKNGAKC-LDGPNTYTCVCTEGYTGTHC 563
PC+ +C + P + C+ G+ +C
Sbjct: 939 LRPPCEAWGECGAEEPPSTPCLPRSGHLDNNC 970
Score = 265 bits (677), Expect = 4e-70
Identities = 170/554 (30%), Positives = 228/554 (41%), Gaps = 89/554 (16%)
Query: 28 GETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYA 86
G+ CLN C+ G C C + G C + N C C++ GTC + V Y
Sbjct: 429 GKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDL----VNGYQ 483
Query: 87 CSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCA 145
C C GF G C D C ++PC +GG C+ L + C CP G+SG C+ D C
Sbjct: 484 CVCPRGFGGRHCELERDE-CASSPCHSGGLCEDLA-DGFHCHCPQGFSGPLCEVDVDLCE 541
Query: 146 SNPCANGGQCLPFEASYICHCPPSFHGPTCR-----------QDVNECGQ---------- 184
+PC NG +C E Y C CP F G C + ++ CG
Sbjct: 542 PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTA 601
Query: 185 KPGLCRHGGTCHNEV-GSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTC---------- 233
G+C G C ++ G++ C+C + TG C C PC+NGGTC
Sbjct: 602 ASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCF 661
Query: 234 RPTG---------------DVTHE------------CACLPGFTGQNCEENIDDCPGNNC 266
P+G D H CAC G+ G+ C C C
Sbjct: 662 CPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTC 721
Query: 267 KNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNG 326
NGG C D +T+ C CPP W G C +PN C NGGTC + ++C+C +G
Sbjct: 722 SNGGTCYDSGDTFRCACPPGWKGSTCAV-AKNSSCLPNPCVNGGTCVGSGASFSCICRDG 780
Query: 327 WTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGS 385
W G C+ N +DC C++G C D V F CEC G G C +N D C S+PC G+
Sbjct: 781 WEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGA 840
Query: 386 NCDTNPVNGKAICTCPSGYTGPACSQDVD---ECSLGANPCEHAGKCINTLGSFECQCLQ 442
C + +NG C+CP G GP C + + C P H + S C+CL
Sbjct: 841 TC-VDEINGYR-CSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNS--CRCLD 896
Query: 443 GYTG---------PRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDE 493
G P E +S C CL++ QC+ P C +E
Sbjct: 897 GRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEK-APGQCLRPPCEAWGEC--GAEE 953
Query: 494 CASSPCLHNGRCLD 507
S+PCL LD
Sbjct: 954 PPSTPCLPRSGHLD 967
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 494 bits (1271), Expect = e-139
Identities = 482/1577 (30%), Positives = 649/1577 (41%), Gaps = 365/1577 (23%)
Query: 101 PLDNACLTNPCRNG---GTCDLLTLTEYKCRCPPGWSGKSC--QQADPCASNPCANGGQC 155
P + C+ CR G C L C C G SC + C+ + C NGG C
Sbjct: 76 PGRSQCVVPICRRACGEGFCSQPNL----CTCADGTLAPSCGVSRGSGCSVS-CMNGGTC 130
Query: 156 LPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNC 215
C C + G C Q + + G C +GG C +G RC C GP C
Sbjct: 131 ----RGASCLCQKGYTGTVCGQPICDRG-----CHNGGRC---IGPNRCACVYGFMGPQC 178
Query: 216 ERPYV--PC----SPSPCQNGGTCRPTGDVTHE---CACLPGFTGQNCEENIDDCPG--N 264
ER Y PC P CQ+ + TG V + CA + G CE CP +
Sbjct: 179 ERDYRTGPCFGQVGPEGCQH----QLTGLVCTKALCCATVGRAWGLPCEL----CPAQPH 230
Query: 265 NCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCV 324
C+ G + ++T C +DVDECQ +P CQ GG+C N G ++C C
Sbjct: 231 PCRRG--FIPNIHTGAC------------QDVDECQAVPGLCQ-GGSCVNMVGSFHCRCP 275
Query: 325 NGWTGEDCSENIDDCASAACF---HGATCHDRVASFY----CECPHGRTGLLCHLNDACI 377
G D S +D + ACF G C +A Y C C GR + + C
Sbjct: 276 VGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCP 335
Query: 378 SNPCNE-------------------------GSNCDTNPV-------NGKAICTCPSGYT 405
NE GSN P+ +G PS
Sbjct: 336 PRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPS--L 393
Query: 406 GPACS--------QDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGP---RCEIDVN 454
GP S Q +D C N C + G+C+ T S+ C+C GYT C IDV+
Sbjct: 394 GPGNSNIGTATLNQTIDICRHFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRGEC-IDVD 451
Query: 455 ECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCE---VNTDEC-ASSPCLHNGRCLDKIN 510
EC S+PC + C++ G + C C PG++ V+ DEC S H GRC++
Sbjct: 452 ECTSSPCHH-GDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEG 510
Query: 511 EFQCECPTGF----TGHLCQYDVDECA-STPCKNGAKCLDGPNTYTCVCTEGY---TGTH 562
FQC C GF G C D +ECA ST C NG CL+ +++C+C G+ G H
Sbjct: 511 SFQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKPGFLLAPGGH 568
Query: 563 CEVDIDECD-PDPCHYGSCKDGVATFTCLCRPGYT----GHHC-ETNI------------ 604
+DIDEC P C G C + +F C C G G C +T++
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGS 628
Query: 605 -----------NECSSQPCRHG-----GTCQDRDNA---YLCFCLKGTTGPNCEINLDDC 645
+EC HG C +D+A LC G T +IN +C
Sbjct: 629 CARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDIN--EC 686
Query: 646 ASSP--CDSGTCLDKIDGYECACEPGY----TGSMCNINIDECAGNP--CHNGGTCEDGI 697
A P C +G C + Y C C GY +G C ++DECA N C N G C++
Sbjct: 687 ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCT-DVDECALNSLLCDN-GWCQNSP 744
Query: 698 NGFTCRCPEGYH---DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGW----SGTNC 750
++C CP G+H D +V+EC S+PCV G CR+ Y C C PG SGT C
Sbjct: 745 GSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFC 804
Query: 751 ----------DINNNECESN---PCVNGGTCKDMTS--GYVC-------TCREGF---SG 785
I + CE N + C + + G C C GF +G
Sbjct: 805 LDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTG 864
Query: 786 PNCQTNINECASNP--CLNQGTCIDDVAGYKCNC----LLPYTGATC-EVVLAPC----- 833
C ++NEC S P C N G C++ ++C C +L +G C +V L PC
Sbjct: 865 VTCD-DVNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWD 922
Query: 834 -------APSPCRN-----------GGECRQSEDYES--FSCVCPTG--------WQGQT 865
P R G EC D ES F+ +CP G G+
Sbjct: 923 EDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRP 982
Query: 866 CEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYS----GRNCETDIDDCRPNPCHNG 919
D+NEC + P C HG +C+NT G + C C G++ RNC TDID+CR +P G
Sbjct: 983 FYKDVNECKVFPGLCTHG-TCRNTVGSFHCACAGGFALDAQERNC-TDIDECRISPDLCG 1040
Query: 920 -GSCTDGINTAFCDCLPGFRGTF-----CEEDINECASDP--CRNGANCTDCVDSYTCTC 971
G+C + + C+C PG+ F C D++ECA DP CR G CT+ SY C C
Sbjct: 1041 QGTCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDPLLCR-GGTCTNTDGSYKCQC 1098
Query: 972 PAGF----SGIHCENNTPDCTESSCFNG----GTCVDGINSFTCLCPPGFTGSYCQH--- 1020
P G G CE D E S +G G CV+ I +F C C GF + +
Sbjct: 1099 PPGHELTAKGTACE----DIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCV 1154
Query: 1021 DVNECDSQPCLHGGTCQDGC----GSYRCTCPQGYT----GPNCQNLVHWCDSSP-CKNG 1071
D+NEC Q G C C GSYRC+C QGY+ G C + V C+ +P +
Sbjct: 1155 DINECRVQ----NGGCDVHCINTEGSYRCSCGQGYSLMPDGRACAD-VDECEENPRVCDQ 1209
Query: 1072 GKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHC 1131
G C +RC C G + P + V ++ +C HG C + + C
Sbjct: 1210 GHCTNMPGGHRCLCYDG----FMATPDMRTCVDVDECDLN-PHICLHGD-CENTKGSFVC 1263
Query: 1132 RCQAGYT----GSYCEDLVDECSPS--PCQNGATCTDYLGGYSCKCVAGY--HGVNCSEE 1183
CQ GY + C D VDEC C + A+C + G +SC+C+ G+ G C +
Sbjct: 1264 HCQLGYMVRKGATGCSD-VDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFEC-HD 1321
Query: 1184 IDECLS--HPCQNGGTCLDLPNTYKCSCPRG--TQGVHCEINVDDCNPPVDPVSRSPKCF 1239
+DEC+S H C G CL++P +Y+C+C +G G CE + D+C VD
Sbjct: 1322 LDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRDECAENVD-------LC 1373
Query: 1240 NNGTCVDQVGGYSCTCPPGF---VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECR 1296
+NG C++ GGY C C GF R DV+EC A G +C F C C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLPGMFRCICN 1431
Query: 1297 AGHT----GRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFE----GATC-EN 1347
G+ G C + C NG V NT ++C CP FE G C +
Sbjct: 1432 GGYELDRGGGNCTDINECADPVNCING----VCINTPGSYLCSCPQDFELNPSGVGCVDT 1487
Query: 1348 DARTCGSLRCLNGGTCIS-------GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQ 1400
A C G + IS G +C C S GNPC
Sbjct: 1488 RAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC-------------SLGRAWGNPC--- 1531
Query: 1401 GTCEPTSESPFYRCLCP 1417
C P + + YR LCP
Sbjct: 1532 ELC-PMANTTEYRTLCP 1547
Score = 484 bits (1246), Expect = e-136
Identities = 483/1683 (28%), Positives = 684/1683 (40%), Gaps = 370/1683 (21%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFV----GPRCQDPNPC-LSTPCKNAGTCHVVD 78
C++ C GG C +G+ C C G C+D + C LS G C V
Sbjct: 1075 CARDPLLC-RGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV- 1132
Query: 79 RRGVADYACSCALGFSGPLCLTPLDNACLT-NPCR--NGGTCDLLTLT---EYKCRCPPG 132
+ + CSC GF TP C+ N CR NGG CD+ + Y+C C G
Sbjct: 1133 ---IGAFQCSCHAGFQS----TPDRQGCVDINECRVQNGG-CDVHCINTEGSYRCSCGQG 1184
Query: 133 WS----GKSCQQADPCASNP-CANGGQCLPFEASYICHCPPSFHGP----TCRQDVNECG 183
+S G++C D C NP + G C + C C F TC DV+EC
Sbjct: 1185 YSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTC-VDVDECD 1243
Query: 184 QKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSP-SPCQNGG-TCRPTGDVTH 241
P +C HG C N GS+ C C+ G + CS C+ GG C +
Sbjct: 1244 LNPHICLHGD-CENTKGSFVCHCQL---GYMVRKGATGCSDVDECEVGGHNCDSHASCLN 1299
Query: 242 -----ECACLPGFTGQNCE-ENIDDCPG--NNCKNGGACVDGVNTYNCRCPPEWTGQ-YC 292
C CLPG+ G E ++D+C + C G C++ +Y C C + G +
Sbjct: 1300 IPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFF 1359
Query: 293 TEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGED---CSENIDDCASAACFHGAT 349
ED DEC + C NG C N GGY C C G+ + +++D+CA +
Sbjct: 1360 CEDRDECAENVDLCDNG-QCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGS 1418
Query: 350 CHDRVASFYCECPHG----RTGLLCH-----------LNDACISNP----CNEGSNCDTN 390
C + F C C G R G C +N CI+ P C+ + + N
Sbjct: 1419 CENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELN 1478
Query: 391 P-----VNGKA----ICTCPSGYTGPACSQDVDE--------CSLG---ANPCE------ 424
P V+ +A + T G +G +CS ++ CSLG NPCE
Sbjct: 1479 PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMAN 1538
Query: 425 ------------------------------------HAGKCINTLGSFECQCLQGYTGPR 448
G C+NT GSF+C+C GY
Sbjct: 1539 TTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 449 ----CEIDVNECVSNP--CQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCL-- 500
CE D++EC ++ C TC + +G + C+C Y V+ N + S C
Sbjct: 1599 HTRICE-DIDECSTHSGIC-GPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRH 1656
Query: 501 HNGRCLDKI--NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTC------ 552
+NG C +++ N + C C Y++ + + PC+ + C
Sbjct: 1657 YNGTCQNELAFNVTRKMC-------CCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPG 1709
Query: 553 VCTEGYTGTHCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHH----CETNINE 606
T+ +TG +DIDEC P C G C + + +F C C G+ + CE +++E
Sbjct: 1710 FLTDIHTGK--PLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDE 1766
Query: 607 CSSQ--PCRHGGTCQDRDNAYLCFCLKG---TTGPNCEINLDDCASSP--CDSGTCLDKI 659
C S+ PC+ C + +Y C C +G + G C + ++C P C G C+D
Sbjct: 1767 CGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTE 1825
Query: 660 DGYECACEPGYTGS----MCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGY---HDPT 712
Y C C G+ S +C ++IDEC PC NG TC++ I + C C G+ H+
Sbjct: 1826 GSYMCLCHRGFQASADQTLC-MDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGD 1883
Query: 713 CLSEVNECNS---NPCVHGACRDSLNGYKCDCDPGWS----GTNCDINNNECES--NPCV 763
C+ + +EC + C G C ++ + C C G+ G NC ++ NEC S C+
Sbjct: 1884 CV-DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCL 1941
Query: 764 NGGTCKDMTSGYVCTCREGFS--GPNCQTNINECASNP--CLNQGTCIDDVAGYKCNC-- 817
G TC+++ + C C GF +C +I+EC+ P CL GTC + ++C C
Sbjct: 1942 PG-TCQNLEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLF-GTCTNSPGSFQCLCPP 1998
Query: 818 -------------------LLPYTGATCEVVLA--------PCAPSPCRNGGE----CRQ 846
+ C V A C+ P G+ C Q
Sbjct: 1999 GFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQ 2058
Query: 847 SEDYESFSCVCPTGWQG----QTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYS 900
E +F +CP G D+NEC +P C +G C NT G +RC C GYS
Sbjct: 2059 -EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRCECPFGYS 2116
Query: 901 ----GRNCETDIDDCRP-NPCHNGGSCTDGINTAFCDCLPGFRGTFCE--EDINECASDP 953
G NC D D+C +PC G +CT+ I C C GF EDI+EC+ +P
Sbjct: 2117 LDFTGINC-VDTDECSVGHPCGQG-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNP 2174
Query: 954 CRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCTESS--CF-NGGTCVDGINSFT 1006
C + SY CTCPAG++ G C + +C + C G C + I +F
Sbjct: 2175 LLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD-VDECADGQQDCHARGMECKNLIGTFA 2233
Query: 1007 CLCPPGF-----TGSYCQHDVNECDSQPCLH-GGTCQDGCGSYRCTCPQGYT-------- 1052
C+CPPG +G C D NEC +QP L G C + GS+RC C +G+
Sbjct: 2234 CVCPPGMRPLPGSGEGCTDD-NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTEC 2292
Query: 1053 -----GP--------NCQNLVHWCDSSP----CKNGGKCWQTHTQYRCE-CPSGWTGLYC 1094
GP C++L ++ C GG+ W RCE CP T Y
Sbjct: 2293 HDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP----RCELCPLPGTSAYR 2348
Query: 1095 DVPSVSCEVAAQRQGVD----VARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLV 1146
+ A+ + VD +A LC HG C+++ + C CQAGYT + C D+
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHLCAHGE-CINSLGSFRCHCQAGYTPDATATTCLDM- 2406
Query: 1147 DECS--PSPCQNGATCTDYLGGYSCKCVAGY----HGVNCSEEIDECLS--HPCQNGGTC 1198
DECS P PC C + G + C C GY G C +++DEC S H CQ C
Sbjct: 2407 DECSQVPKPCT--FLCKNTKGSFLCSCPRGYLLEEDGRTC-KDLDECTSRQHNCQF--LC 2461
Query: 1199 LDLPNTYKCSCPRG-TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPP 1257
++ + C CP G TQ + D+C+ P C +G C + G + C C
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGP------CGAHGHCHNTPGSFRCECHQ 2515
Query: 1258 GFV----GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGR----RCESVIN 1309
GF G CE DVNEC P R C ++ + C C G T +C N
Sbjct: 2516 GFTLVSSGHGCE-DVNEC-DGP--HRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDE-N 2570
Query: 1310 GCKGKPCKNGGTCAVAS--NTARGFICKCPAGFE-----GATCENDARTCGSLRCLNGGT 1362
C P TC AS NT GF C CP+GF+ G E D C R +
Sbjct: 2571 ECALSP----PTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVD--ECAGRRGPCSYS 2624
Query: 1363 CISGPRSPTCLC---------------LGPFTGPECQFPASSPCLGGNPCYNQGTCEPTS 1407
C + P C C LG GP+ P L CY C+
Sbjct: 2625 CANTPGGFLCGCPQGYFRAGQGHCVSGLGFSPGPQ-DTPDKEELLSSEACYE---CKING 2680
Query: 1408 ESP 1410
SP
Sbjct: 2681 LSP 2683
Score = 471 bits (1211), Expect = e-132
Identities = 515/1852 (27%), Positives = 701/1852 (37%), Gaps = 395/1852 (21%)
Query: 10 CLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGA-FVGPRCQDPNPCLSTP- 67
C L + R C+ G G CE AC G A G C D N C S P
Sbjct: 821 CEVNLQGASLRSECCATLGAAW--GSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 68 -CKNAGTCHVVDRRGVADYACSCALGF----SGPLCLTPLDNACLTNPCRNGGTCDLLTL 122
C N G C V+ G + C C G SG LC+ C + C +
Sbjct: 879 VCPN-GRC--VNTAG--SFRCECPEGLMLDASGRLCVDVRLEPCFLR--WDEDECGVTLP 931
Query: 123 TEYK---CRCPPG--WSGKSCQQA-DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCR 176
+Y+ C C G W G C+ DP + + + L F + P +
Sbjct: 932 GKYRMDVCCCSIGAVW-GVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFY------ 984
Query: 177 QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP---CSPSPCQNG-GT 232
+DVNEC PGLC HG TC N VGS+ C C ER C SP G GT
Sbjct: 985 KDVNECKVFPGLCTHG-TCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGT 1043
Query: 233 CRPTGDVTHECACLPGFTG-----QNCEENIDDCPGNN--CKNGGACVDGVNTYNCRCPP 285
C T + EC C PG+ +NC + +D+C + C+ GG C + +Y C+CPP
Sbjct: 1044 CVNTPG-SFECECFPGYESGFMLMKNCMD-VDECARDPLLCR-GGTCTNTDGSYKCQCPP 1100
Query: 286 --EWT--GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCAS 341
E T G C ED+DEC L C +G C N G + C C G+ + D
Sbjct: 1101 GHELTAKGTAC-EDIDECSLSDGLCPHG-QCVNVIGAFQCSCHAGFQSTPDRQGCVDINE 1158
Query: 342 AACFHGAT---CHDRVASFYCECPHGRT----GLLCHLNDACISNP--CNEG-------- 384
+G C + S+ C C G + G C D C NP C++G
Sbjct: 1159 CRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG 1218
Query: 385 ---------------------SNCDTNP----------VNGKAICTCPSGYT---GPACS 410
CD NP G +C C GY G
Sbjct: 1219 HRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGC 1278
Query: 411 QDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEI-DVNECVS--NPCQNDATC 467
DVDEC +G + C+ C+N GSF C+CL G+ G E D++ECVS + C C
Sbjct: 1279 SDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDC 1338
Query: 468 LDQIGEFQCICMPGY--EGVHCEVNTDECASSPCL-HNGRCLDKINEFQCECPTGF---T 521
L+ G ++C C G+ +G CE + DECA + L NG+CL+ ++CEC GF
Sbjct: 1339 LNVPGSYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTE 1397
Query: 522 GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYT----GTHCEVDIDEC-DPDPCH 576
H DVDECA C + P + C+C GY G +C DI+EC DP C
Sbjct: 1398 DHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNC-TDINECADPVNCI 1456
Query: 577 YGSCKDGVATFTCLCRPGY----TGHHC-ETNINECSSQPCRHGGTCQDRDNAYLCFCL- 630
G C + ++ C C + +G C +T C + G D+ C
Sbjct: 1457 NGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRG------DSGISCSAEI 1510
Query: 631 -KGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCN------INIDECA 683
G T +C +L +PC+ + + Y C PG G N +IDEC
Sbjct: 1511 GVGVTRASCCCSLGRAWGNPCELCPMANTTE-YRTLC-PGGEGFQPNRITVILEDIDECQ 1568
Query: 684 GNP-CHNGGTCEDGINGFTCRCPEGYH---DPTCLSEVNEC--NSNPCVHGACRDSLNGY 737
P GG C + F C CP GYH +++EC +S C G C ++L Y
Sbjct: 1569 ELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNY 1628
Query: 738 KCDCDPGWSGTNCDINNNECESNPCVN--GGTCKDMTSGYV----CTCR----EGFSGP- 786
C C + N N + + C GTC++ + V C C + ++ P
Sbjct: 1629 TCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPC 1688
Query: 787 -NCQT---------------------------NINECASNP--CLNQGTCIDDVAGYKCN 816
C T +I+EC P C N G CI+ + ++C
Sbjct: 1689 EACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICAN-GICINQIGSFRCE 1747
Query: 817 CLLPYTGATCEVVLAPC--------APSPCRNGGECRQSEDYESFSCVCPTGWQ---GQT 865
C G +L C SPC+ +C S+ C C G++ G
Sbjct: 1748 C---PAGFNYNSILLACEDVDECGSRESPCQQNADCINIPG--SYRCKCTRGYKLSPGGA 1802
Query: 866 CEVDINEC--VLSPCRHGASCQNTHGGYRCHCQAGYSGRNCET---DIDDCRPNPCHNGG 920
C V NEC + + C HG C +T G Y C C G+ +T DID+C PC N G
Sbjct: 1803 C-VGRNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGN-G 1859
Query: 921 SCTDGINTAFCDCLPGFRGTFCEE--DINECAS---DPCRNGANCTDCVDSYTCTCPAGF 975
+C + I + C C PGF T + D +EC + CR G +C + S+ C C GF
Sbjct: 1860 TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFG-HCLNTAGSFHCLCQDGF 1918
Query: 976 SGIHCENNTPDCTESSCFNG----GTCVDGINSFTCLCPPGF--TGSYCQHDVNECDSQP 1029
N D E G GTC + SF C+CPPGF +C D++EC +P
Sbjct: 1919 ELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHC-IDIDECSEEP 1977
Query: 1030 --CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPC---KNGGKCWQ----THTQ 1080
CL GTC + GS++C CP G+ + + S C GKC T+
Sbjct: 1978 NLCLF-GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTK 2036
Query: 1081 YRCECP----SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG----------------- 1119
RC C GW CE+ Q LC G
Sbjct: 2037 TRCCCSKRPGEGW--------GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNEC 2088
Query: 1120 ---------GLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS-PCQNGATCTDYLG 1165
G+CV+ + C C GY TG C D DECS PC G TCT+ +G
Sbjct: 2089 AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD-TDECSVGHPCGQG-TCTNVIG 2146
Query: 1166 GYSCKCVAGYHG--VNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG----TQGVHCE 1219
G+ C C G+ + E+IDEC +P C + +Y C+CP G G C
Sbjct: 2147 GFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR 2206
Query: 1220 INVDDCNPPVDPVSRSPKCFNNG-TCVDQVGGYSCTCPPGF-----VGERCEGDVNECLS 1273
+VD+C C G C + +G ++C CPPG GE C D NEC +
Sbjct: 2207 -DVDEC------ADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDD-NECHA 2258
Query: 1274 NPCDARGTQNCVQRVNDFHCECRAGH----TGRRCESVING------------------- 1310
P D CV F C+C G T C + G
Sbjct: 2259 QP-DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSE 2317
Query: 1311 --CKGKPCKNGG--------TCAVASNTARGFICKCPAGFEGATCE-NDARTCGSLRCLN 1359
+ + C GG C + +A + CP G G T E D C L L
Sbjct: 2318 AVTRAECCCGGGRGWGPRCELCPLPGTSA--YRKLCPHG-SGYTAEGRDVDECRMLAHLC 2374
Query: 1360 G-GTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYN-----QGTCEPTSESPFYR 1413
G CI+ S C C +T P+ ++ CL + C C+ T S +
Sbjct: 2375 AHGECINSLGSFRCHCQAGYT-PDA---TATTCLDMDECSQVPKPCTFLCKNTKGS--FL 2428
Query: 1414 CLCPAKF----NGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQC-- 1467
C CP + +G C LD E CQ N V + C
Sbjct: 2429 CSCPRGYLLEEDGRTCKDLD----------------ECTSRQHNCQFLCVNTVGAFTCRC 2472
Query: 1468 -----NNHACGWDGGDCSLN----------FNDPWKNCTQSLQCWKYFSDGH-CD--SQC 1509
+H +D +CS N P + Q + S GH C+ ++C
Sbjct: 2473 PPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532
Query: 1510 NSA-----GC--LFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAEC 1554
+ GC G+ C +G C D C SA C
Sbjct: 2533 DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASC 2584
Score = 459 bits (1182), Expect = e-128
Identities = 479/1697 (28%), Positives = 691/1697 (40%), Gaps = 380/1697 (22%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAF---VGPRCQDPNPCLSTPCKNAGTCHVVDRR 80
C CLNG +C + C C + V C D + C S+PC + ++
Sbjct: 412 CRHFTNLCLNG-RCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIP--- 467
Query: 81 GVADYACSCALGFSGPLCLTPLDNACL-TNPCR-NGGTCDL----LTLTEYKCRCPPGWS 134
Y C C GF TP AC+ + C +GG C L T ++C C G+
Sbjct: 468 --GTYHCRCYPGFQA----TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFE 521
Query: 135 ----GKSCQQADPCASNPCANGGQCLPFEASYICHCPPSF----HGPTCRQDVNECGQKP 186
GK+C + CA++ G CL + S+ C C P F G C D++EC Q P
Sbjct: 522 LSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC-MDIDEC-QTP 579
Query: 187 GLCRHGGTCHNEVGSYRC-------------VCRATHTGP---------NCERPY---VP 221
G+C + G C N GS+RC VC TH +C RP+ V
Sbjct: 580 GICVN-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVT 638
Query: 222 CSPSPCQN-----GGTCR--PTGD-VTHECACLPGFTGQNCEENIDDC--PGNNCKNGGA 271
S C N G C+ P D + C G +I++C C N G
Sbjct: 639 KSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCAN-GV 697
Query: 272 CVDGVNTYNCRCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNG- 326
C + +Y C C + +G+ CT DVDEC L C N G C N+ G Y+C C G
Sbjct: 698 CENLRGSYRCVCNLGYEAGASGKDCT-DVDECALNSLLCDN-GWCQNSPGSYSCSCPPGF 755
Query: 327 --WTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGR----TGLLC---------- 370
W + +++D+C S+ C G C + S+ C+C G +G C
Sbjct: 756 HFWQDTEICKDVDECLSSPCVSG-VCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWL 814
Query: 371 ---------HLNDACISNPCNE------GSNCDTNPVNGKAICTCPSGY---TGPACSQD 412
+L A + + C GS C+ ++ C G+ TG C D
Sbjct: 815 KIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDP----ACARGFARMTGVTC-DD 869
Query: 413 VDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNECVSNPC----QND 464
V+EC C + G+C+NT GSF C+C +G +G C +DV PC D
Sbjct: 870 VNECESFPGVCPN-GRCVNTAGSFRCECPEGLMLDASGRLC-VDVR---LEPCFLRWDED 924
Query: 465 ATCLDQIGEFQ---CICMPG-YEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTG- 519
+ G+++ C C G GV CE C L EF CP G
Sbjct: 925 ECGVTLPGKYRMDVCCCSIGAVWGVECEA----CPDPESL----------EFASLCPRGL 970
Query: 520 -------FTGHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYTGTHCE---VDI 567
+G DV+EC P C +G C + ++ C C G+ E DI
Sbjct: 971 GFASRDFLSGRPFYKDVNECKVFPGLCTHGT-CRNTVGSFHCACAGGFALDAQERNCTDI 1029
Query: 568 DEC--DPDPCHYGSCKDGVATFTCLCRPGYTG-----HHCETNINECSSQP--CRHGGTC 618
DEC PD C G+C + +F C C PGY +C +++EC+ P CR GGTC
Sbjct: 1030 DECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDPLLCR-GGTC 1087
Query: 619 QDRDNAYLCFCLKG----TTGPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYTG 672
+ D +Y C C G G CE ++D+C+ S C G C++ I ++C+C G+
Sbjct: 1088 TNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQS 1146
Query: 673 SMCN---INIDECAGNPCHNGGT---CEDGINGFTCRCPEGYH---DPTCLSEVNECNSN 723
+ ++I+EC NGG C + + C C +GY D ++V+EC N
Sbjct: 1147 TPDRQGCVDINECR---VQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEEN 1203
Query: 724 P--CVHGACRDSLNGYKCDCDPGWSGT---NCDINNNECESNP--CVNGGTCKDMTSGYV 776
P C G C + G++C C G+ T ++ +EC+ NP C++ G C++ +V
Sbjct: 1204 PRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLH-GDCENTKGSFV 1262
Query: 777 CTCREGF---SGPNCQTNINEC--ASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEV-VL 830
C C+ G+ G ++++EC + C + +C++ + C CL + G E L
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 831 APCAPSP--CRNGGECRQSEDYESFSCVCPTGWQGQ--TCEVDINECV--LSPCRHGASC 884
C C G+C S+ C C G+ G CE D +EC + C +G C
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPG--SYRCTCRQGFAGDGFFCE-DRDECAENVDLCDNG-QC 1378
Query: 885 QNTHGGYRCHCQAGY----SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGF--- 937
N GGYRC C+ G+ R C+ D+D+C GSC + C C G+
Sbjct: 1379 LNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAFGSCENLPGMFRCICNGGYELD 1437
Query: 938 RGTFCEEDINECASDP--CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDCTESS 991
RG DINECA DP C NG C + SY C+CP F SG+ C D +
Sbjct: 1438 RGGGNCTDINECA-DPVNCINGV-CINTPGSYLCSCPQDFELNPSGVGC----VDTRAGN 1491
Query: 992 CF--------NGGTCVD----GINSFTC-------------LCPPGFTGSY--------- 1017
CF +G +C G+ +C LCP T Y
Sbjct: 1492 CFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEG 1551
Query: 1018 --------CQHDVNECDSQPCL-HGGTCQDGCGSYRCTCPQGYTGPN----CQNLVHWCD 1064
D++EC P L GG C + GS++C CP GY C+++
Sbjct: 1552 FQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECST 1611
Query: 1065 SSPCKNGGKCWQTHTQYRCECPSGWT----GLYC-DVPSVSC----------EVA----- 1104
S G C+ T Y C CP+ + G C D+ C E+A
Sbjct: 1612 HSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTR 1671
Query: 1105 -----AQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG------YTGSYCEDLVDECS--P 1151
+ G R C+ + C QA +TG + +DEC P
Sbjct: 1672 KMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLD--IDECGEIP 1729
Query: 1152 SPCQNGATCTDYLGGYSCKCVAGYHG---VNCSEEIDECLSH--PCQNGGTCLDLPNTYK 1206
+ C NG C + +G + C+C AG++ + E++DEC S PCQ C+++P +Y+
Sbjct: 1730 AICANG-ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYR 1788
Query: 1207 CSCPRG---TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGER 1263
C C RG + G C + ++C P ++G C+D G Y C C GF
Sbjct: 1789 CKCTRGYKLSPGGAC-VGRNECR-------EIPNVCSHGDCMDTEGSYMCLCHRGFQASA 1840
Query: 1264 CEG---DVNECLSNPCDARGTQNCVQRVNDFHCECRAG----HTG-----RRCESVINGC 1311
+ D++EC PC G C + ++C C G H G C +++
Sbjct: 1841 DQTLCMDIDECDRQPC---GNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLV--- 1894
Query: 1312 KGKPCKNGGTCAVASNTARGFICKCPAGFE----GATCENDARTCGSL--RCLNGGTCIS 1365
G+ C+ G NTA F C C GFE G C D C SL CL GTC +
Sbjct: 1895 -GQVCRFGH----CLNTAGSFHCLCQDGFELTADGKNCV-DTNECLSLAGTCL-PGTCQN 1947
Query: 1366 GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQ------GTCEPTSESPFYRCLCPAK 1419
S C+C F S C+ + C + GTC T+ ++CLCP
Sbjct: 1948 LEGSFRCICPPGFQ------VQSDHCIDIDECSEEPNLCLFGTC--TNSPGSFQCLCPPG 1999
Query: 1420 F----NGLLCHILDYSF 1432
F NG C SF
Sbjct: 2000 FVLSDNGHRCFDTRQSF 2016
Score = 422 bits (1084), Expect = e-117
Identities = 379/1291 (29%), Positives = 512/1291 (39%), Gaps = 226/1291 (17%)
Query: 23 RCSQPGETCLNG-----GKCEAANGTEACVCGGAFVGPR----------CQDPNPCLSTP 67
R Q + C G G CE G C+C G + R C DP C++
Sbjct: 1400 RACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGV 1459
Query: 68 CKN--------------------------AGTCHVVDR-RGVADYACSCALGF--SGPLC 98
C N AG C + RG + +CS +G + C
Sbjct: 1460 CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASC 1519
Query: 99 LTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKS------CQQADPCASNP-CAN 151
L A NPC C + TEY+ CP G + + D C P
Sbjct: 1520 CCSLGRAW-GNPCE---LCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQ 1575
Query: 152 GGQCLPFEASYICHCPPSFH---GPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
GG C+ S+ C CPP +H +D++EC G+C G TC+N +G+Y CVC A
Sbjct: 1576 GGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPG-TCYNTLGNYTCVCPA 1634
Query: 209 THTGPNCERPYVPCSPSPC--QNGGTCRP--TGDVTHECACLPGFTGQNCEENIDDCP-- 262
+ N + S C GTC+ +VT + C GQ + CP
Sbjct: 1635 EYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTP 1694
Query: 263 ---------GNN-------------------------CKNGGACVDGVNTYNCRCPPEWT 288
GN C NG C++ + ++ C CP +
Sbjct: 1695 ISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANG-ICINQIGSFRCECPAGFN 1753
Query: 289 GQ---YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT---GEDCSENIDDCASA 342
EDVDEC + CQ C N G Y C C G+ G C ++C
Sbjct: 1754 YNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGR-NECREI 1812
Query: 343 --ACFHGATCHDRVASFYCECPHGRTG----LLCHLNDACISNPCNEGSNCDTNPVNGKA 396
C HG C D S+ C C G LC D C PC G+ + G
Sbjct: 1813 PNVCSHG-DCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT---CKNIIGSY 1868
Query: 397 ICTCPSGY--TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----GPRCE 450
C C G+ T D DEC+ G C+NT GSF C C G+ G C
Sbjct: 1869 NCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC- 1927
Query: 451 IDVNECVS--NPCQNDATCLDQIGEFQCICMPGYE--GVHCEVNTDECASSP--CLHNGR 504
+D NEC+S C TC + G F+CIC PG++ HC ++ DEC+ P CL G
Sbjct: 1928 VDTNECLSLAGTCL-PGTCQNLEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLF-GT 1984
Query: 505 CLDKINEFQCECPTGFT----GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTG 560
C + FQC CP GF GH C +D + KC P + T
Sbjct: 1985 CTNSPGSFQCLCPPGFVLSDNGHRC-FDTRQSFCFTRFEAGKC-SVPKAFNTTKTR---- 2038
Query: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTG----HHCETNINECSSQP--CRH 614
C E DPC ++G A F LC G+ ++NEC+ P C +
Sbjct: 2039 CCCSKRPGEGWGDPCELCP-QEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTN 2097
Query: 615 GGTCQDRDNAYLCFCLKGT----TGPNCEINLDDCA-SSPCDSGTCLDKIDGYECACEPG 669
G C + D ++ C C G TG NC ++ D+C+ PC GTC + I G+ECAC G
Sbjct: 2098 G-VCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Query: 670 YTGSMCNI--NIDECAGNPCHNGGTCEDGINGFTCRCPEGY---HDPTCLSEVNEC-NSN 723
+ + +IDEC+ NP C + + C CP GY D +V+EC +
Sbjct: 2156 FEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ 2215
Query: 724 PCVHGA---CRDSLNGYKCDCDPGW-----SGTNCDINNNECESNP--CVNGGTCKDMTS 773
H C++ + + C C PG SG C ++NEC + P CVNG C +
Sbjct: 2216 QDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT-DDNECHAQPDLCVNG-RCVNTAG 2273
Query: 774 GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPC 833
+ C C EGF + EC + QG C +V C L + A V A C
Sbjct: 2274 SFRCDCDEGFQP---SPTLTECHD---IRQGPCFAEVLQTMCRSLSSSSEA---VTRAEC 2324
Query: 834 APSPCRNGG---ECRQSEDYESFSCVCPTGWQGQTCEV-DINECVLSP--CRHGASCQNT 887
R G E ++ +CP G G T E D++EC + C HG C N+
Sbjct: 2325 CCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYTAEGRDVDECRMLAHLCAHG-ECINS 2382
Query: 888 HGGYRCHCQAGYSGRNCET---DIDDCR--PNPCHNGGSCTDGINTAFCDCLPGFR---- 938
G +RCHCQAGY+ T D+D+C P PC C + + C C G+
Sbjct: 2383 LGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTF--LCKNTKGSFLCSCPRGYLLEED 2440
Query: 939 GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIH---CENNTPDCTESSCFNG 995
G C+ D++EC S C + V ++TC CP GF+ H +N+ C
Sbjct: 2441 GRTCK-DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAH 2499
Query: 996 GTCVDGINSFTCLCPPGFT----GSYCQHDVNECDS-QPCLHGGTCQDGCGSYRCTCPQG 1050
G C + SF C C GFT G C+ DVNECD C HG CQ+ G YRC+CPQG
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQG 2556
Query: 1051 YT----GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQ 1106
+T C + S P C T +RC CPSG+ + A
Sbjct: 2557 FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAG 2616
Query: 1107 RQGVDVARLCQHGGLCVDAGNTHHCRCQAGY 1137
R+G C + C + C C GY
Sbjct: 2617 RRGP-----CSYS--CANTPGGFLCGCPQGY 2640
Score = 355 bits (911), Expect = 3e-97
Identities = 402/1493 (26%), Positives = 575/1493 (38%), Gaps = 297/1493 (19%)
Query: 186 PGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECAC 245
PG+ + C + +Y C T P + VP C G +P + C C
Sbjct: 51 PGILQGPNVCGSRFHAY--CCPGWRTFPGRSQCVVPICRRACGEGFCSQP-----NLCTC 103
Query: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNA 305
G +C + +C NGG C +C C +TG C + + +
Sbjct: 104 ADGTLAPSCGVSRGSGCSVSCMNGGTCRGA----SCLCQKGYTGTVCGQPICD-----RG 154
Query: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGR 365
C NGG C G C CV G+ G C + + C +V C+ H
Sbjct: 155 CHNGGRCI---GPNRCACVYGFMGPQCERD---------YRTGPCFGQVGPEGCQ--HQL 200
Query: 366 TGLLCHLNDACISNPCNEGSNCDTNPVNGKAICT--CPSGYTGPACSQDVDECSLGANPC 423
TGL+C C + G C+ P P+ +TG AC QDVDEC C
Sbjct: 201 TGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTG-AC-QDVDECQAVPGLC 258
Query: 424 EHAGKCINTLGSFECQCLQGY----TGPRCE-IDVNECVS----NPCQNDAT-------- 466
+ G C+N +GSF C+C G+ + CE C S C D
Sbjct: 259 Q-GGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQC 317
Query: 467 CLDQ-----------------IGEFQCIC------MPGYEGVHCEV----------NTDE 493
C D+ EFQ +C +PG+ G+ +
Sbjct: 318 CCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGP 377
Query: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCV 553
+P + R + + T D+ + C NG +CL P++Y C
Sbjct: 378 ARLNPHGSDARGIPSLGPGNSNIGTATLNQTI--DICRHFTNLCLNG-RCLPTPSSYRCE 434
Query: 554 CTEGYTGT---HCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGY----TGHHCETNINE 606
C GYT C +D+DEC PCH+G C + T+ C C PG+ T C +++E
Sbjct: 435 CNVGYTQDVRGEC-IDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQAC-VDVDE 492
Query: 607 C--SSQPCRHGGTCQDRDNAYLCFCLKG----TTGPNCEINLDDCASSP-CDSGTCLDKI 659
C S C H G C + + ++ C C G G NC ++ ++CA+S C +G CL++
Sbjct: 493 CIVSGGLC-HLGRCVNTEGSFQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNED 550
Query: 660 DGYECACEPGYT----GSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLS 715
+ C C+PG+ G C ++IDEC G C + F C+C G T
Sbjct: 551 GSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGT--- 606
Query: 716 EVNECNSNPCVHGACRDSLNG--YKCDCDPGWSGTNCDINNNECESNPCVN-----GGTC 768
+ CV R + G K C + GT + +EC C N G C
Sbjct: 607 -----DGRVCVDTHVRSTCYGAIEKGSCARPFPGT---VTKSEC---CCANPDHGFGEPC 655
Query: 769 -----KDMTSGYVCTCREGFSGPNCQTNINECASNP--CLNQGTCIDDVAGYKCNCLLPY 821
KD ++ + C G +INECA +P C N G C + Y+C C L Y
Sbjct: 656 QLCPAKD-SAEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRGSYRCVCNLGY 713
Query: 822 ----TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTG---WQGQTCEVDINECV 874
+G C V S + G C+ S S+SC CP G WQ D++EC+
Sbjct: 714 EAGASGKDCTDVDECALNSLLCDNGWCQNSPG--SYSCSCPPGFHFWQDTEICKDVDECL 771
Query: 875 LSPCRHGASCQNTHGGYRCHCQAGY----SGR--------NCETDIDDCRPNPCHNGGS- 921
SPC G C+N G Y C C G SG C I + R G S
Sbjct: 772 SSPCVSGV-CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASL 830
Query: 922 ---CTDGINTAF---CD-------CLPGF---RGTFCEEDINECASDP--CRNGANCTDC 963
C + A+ C+ C GF G C +D+NEC S P C NG C +
Sbjct: 831 RSECCATLGAAWGSPCERCEIDPACARGFARMTGVTC-DDVNECESFPGVCPNG-RCVNT 888
Query: 964 VDSYTCTCPAGF----SGIHCEN----------NTPDC--TESSCFNGGTCVDGINS--- 1004
S+ C CP G SG C + + +C T + C I +
Sbjct: 889 AGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWG 948
Query: 1005 -------------FTCLCPPG--------FTGSYCQHDVNECDSQP--CLHGGTCQDGCG 1041
F LCP G +G DVNEC P C H GTC++ G
Sbjct: 949 VECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTH-GTCRNTVG 1007
Query: 1042 SYRCTCPQGYT----GPNCQNLVHWCDSSPCKNG-GKCWQTHTQYRCECPSGWTGLYCDV 1096
S+ C C G+ NC + + C SP G G C T + CEC G+ + +
Sbjct: 1008 SFHCACAGGFALDAQERNCTD-IDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLM 1066
Query: 1097 PSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGY----TGSYCEDLVDECSPS 1152
+ R + LC+ GG C + ++ C+C G+ G+ CED +DECS S
Sbjct: 1067 KNCMDVDECARDPL----LCR-GGTCTNTDGSYKCQCPPGHELTAKGTACED-IDECSLS 1120
Query: 1153 P--CQNGATCTDYLGGYSCKCVAGYHGVNCSE---EIDECLSHPCQNGGT---CLDLPNT 1204
C +G C + +G + C C AG+ + +I+EC QNGG C++ +
Sbjct: 1121 DGLCPHG-QCVNVIGAFQCSCHAGFQSTPDRQGCVDINEC---RVQNGGCDVHCINTEGS 1176
Query: 1205 YKCSCPRG----TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260
Y+CSC +G G C +VD+C +P+ + G C + GG+ C C GF+
Sbjct: 1177 YRCSCGQGYSLMPDGRAC-ADVDEC-------EENPRVCDQGHCTNMPGGHRCLCYDGFM 1228
Query: 1261 GE---RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRR----CESVINGCK- 1312
R DV+EC NP +C F C C+ G+ R+ C S ++ C+
Sbjct: 1229 ATPDMRTCVDVDECDLNPHICL-HGDCENTKGSFVCHCQLGYMVRKGATGC-SDVDECEV 1286
Query: 1313 -GKPCKNGGTCAVASNTARGFICKCPAGFEGATCE-NDARTCGSL--RCLNGGTCISGPR 1368
G C + +C N F C+C G+ G E +D C S RC G C++ P
Sbjct: 1287 GGHNCDSHASCL---NIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 1369 SPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHIL 1428
S C C F G C + G C + YRC C F+ H
Sbjct: 1344 SYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQC--LNAPGGYRCECEMGFDPTEDH-- 1399
Query: 1429 DYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCN-NHACGWDGGDCS 1480
A +D+ C C+ G C CN + GG+C+
Sbjct: 1400 ------RACQDVDECAQGNLCAFGSCENLPGMFRCI--CNGGYELDRGGGNCT 1444
Score = 343 bits (881), Expect = 1e-93
Identities = 405/1508 (26%), Positives = 567/1508 (37%), Gaps = 379/1508 (25%)
Query: 303 PNACQNGGTCHNTHGGYNCVCVNGW-TGEDCSENIDDCASAACFHGATCHDRVASFYCEC 361
P Q C + Y C GW T S+ + AC G +C
Sbjct: 51 PGILQGPNVCGSRFHAY---CCPGWRTFPGRSQCVVPICRRACGEG----------FCSQ 97
Query: 362 PHGRTGLLCHLNDACISNPC--NEGSNCDTNPVNGK----AICTCPSGYTGPACSQDVDE 415
P+ LC D ++ C + GS C + +NG A C C GYTG C Q +
Sbjct: 98 PN-----LCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPI-- 150
Query: 416 CSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVN------ECVSNPCQNDATCLD 469
C G C + G+CI G C C+ G+ GP+CE D + CQ+ T L
Sbjct: 151 CDRG---CHNGGRCI---GPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLV 204
Query: 470 QIGEFQCICMPGYEGVHCEV----------------------NTDECASSPCL-HNGRCL 506
C + G+ CE+ + DEC + P L G C+
Sbjct: 205 CTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCV 264
Query: 507 DKINEFQCECPTGF----TGHLCQ-YDVDECASTPCKNGAKCL-DGPNTYT---CVCTEG 557
+ + F C CP G + C+ Y C S G +C D YT C C G
Sbjct: 265 NMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLF--GGRCAGDLAGHYTRRQCCCDRG 322
Query: 558 YTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCR------PGYTGHH-----CETNINE 606
V + C P G F LC PG+ G +N
Sbjct: 323 RCWAAGPVP-ELCPPR---------GSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMG 372
Query: 607 CSSQPCR---HGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYE 663
P R HG + + GT N I++ ++ C +G CL Y
Sbjct: 373 PPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYR 432
Query: 664 CACEPGYTGSMCN--INIDECAGNPCHNGGTCEDGINGFTCRCPEGYH-DPT--CLSEVN 718
C C GYT + I++DEC +PCH+ G C + + CRC G+ PT +V+
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHH-GDCVNIPGTYHCRCYPGFQATPTRQACVDVD 491
Query: 719 EC--NSNPCVHGACRDSLNGYKCDCDPGW----SGTNCDINNNEC-ESNPCVNGGTCKDM 771
EC + C G C ++ ++C C+ G+ G NC +++NEC S CVN G C +
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-VDHNECATSTMCVN-GVCLNE 549
Query: 772 TSGYVCTCREGF---SGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL----LPYTGA 824
+ C C+ GF G + +I+EC + G C + ++C CL + G
Sbjct: 550 DGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 825 TC-----------EVVLAPCA-PSP---------CRN-----GGECR--QSEDYESFSCV 856
C + CA P P C N G C+ ++D F +
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQAL 669
Query: 857 CPTGWQGQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDD 910
C +G T DINEC L P C +G C+N G YRC C GY SG++C TD+D+
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASGKDC-TDVDE 727
Query: 911 CRPNP--CHNGGSCTDGINTAFCDCLPGF---RGTFCEEDINECASDPCRNGANCTDCVD 965
C N C NG C + + C C PGF + T +D++EC S PC +G C +
Sbjct: 728 CALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV-CRNLAG 785
Query: 966 SYTCTCPAGF----SGIHCENNTP-----DCTESSC--------FNGGTCVD-----GIN 1003
SYTC C G SG C ++T ES C C G
Sbjct: 786 SYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSP 845
Query: 1004 SFTC----LCPPGF---TGSYCQHDVNECDSQP-CLHGGTCQDGCGSYRCTCPQGYTGPN 1055
C C GF TG C DVNEC+S P G C + GS+RC CP+G
Sbjct: 846 CERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDA 904
Query: 1056 CQNLVHWCDSSPC---KNGGKCWQT-HTQYR---CECPSGWTGLYCDVPSVSCEVAAQRQ 1108
L PC + +C T +YR C C G V V CE +
Sbjct: 905 SGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIG------AVWGVECEACPDPE 958
Query: 1109 GVDVARLCQHG------------------------------GLCVDAGNTHHCRCQAGYT 1138
++ A LC G G C + + HC C G+
Sbjct: 959 SLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFA 1018
Query: 1139 ----GSYCEDLVDEC--SPSPCQNGATCTDYLGGYSCKCVAGYHG-----VNCSEEIDEC 1187
C D +DEC SP C G TC + G + C+C GY NC ++DEC
Sbjct: 1019 LDAQERNCTD-IDECRISPDLCGQG-TCVNTPGSFECECFPGYESGFMLMKNCM-DVDEC 1075
Query: 1188 LSHPCQ-NGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPVDPVSRSPKCFNNG 1242
P GGTC + +YKC CP G +G CE ++D+C S S +G
Sbjct: 1076 ARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDEC-------SLSDGLCPHG 1127
Query: 1243 TCVDQVGGYSCTCPPGFVG----ERCEGDVNEC--LSNPCDARGTQNCVQRVNDFHCECR 1296
CV+ +G + C+C GF + C D+NEC + CD +C+ + C C
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCV-DINECRVQNGGCDV----HCINTEGSYRCSCG 1182
Query: 1297 AGHT----GRRCESVINGCKGKP-------CKN--GG----------------TC----- 1322
G++ GR C V + C+ P C N GG TC
Sbjct: 1183 QGYSLMPDGRACADV-DECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDE 1241
Query: 1323 ----------AVASNTARGFICKCPAGF---EGATCENDARTC--GSLRCLNGGTCISGP 1367
NT F+C C G+ +GAT +D C G C + +C++ P
Sbjct: 1242 CDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIP 1301
Query: 1368 RSPTCLCLGPFTGPECQFPASSPCLG-GNPCYNQGTCEPTSESPFYRCLCPAKF--NGLL 1424
S +C CL + G + C+ + C +G C S YRC C F +G
Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGS--YRCTCRQGFAGDGFF 1359
Query: 1425 CHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHAC-GWDGG---DCS 1480
C D EC E+ C+N C GG +C
Sbjct: 1360 CEDRD-----------------------ECAENVD------LCDNGQCLNAPGGYRCECE 1390
Query: 1481 LNFNDPWKN---------CTQSLQCWKYFSDGHCDSQCNSAGCLFD-GFDCQRAEGQCNP 1530
+ F DP ++ C Q C + G C++ C+ + G++ R G C
Sbjct: 1391 MGF-DPTEDHRACQDVDECAQGNLC----AFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Query: 1531 LYDQYCKD 1538
+ + C D
Sbjct: 1446 INE--CAD 1451
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 481 bits (1239), Expect = e-135
Identities = 250/706 (35%), Positives = 350/706 (49%), Gaps = 71/706 (10%)
Query: 531 ECASTPCKNGAKCLDGPNTYT--CVCTEGYTGTHCEVDIDECDPDP-CHYGSCKDGVATF 587
EC CK G L G T C C+ G+ G C DEC P P C +GSC V +
Sbjct: 239 ECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGCVHGSC---VEPW 291
Query: 588 TCLCRPGYTGHHCETNINECSSQ-PCRHGGTCQDRD-NAYLCFCLKGTTGPNCEINLDDC 645
C C + G C+ ++N C S PC +GGTC + + + Y C C G +G NCE C
Sbjct: 292 QCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHAC 351
Query: 646 ASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRC 704
S+PC + G+C + G+EC C G++G C ++IDECA NPC GGTC D ++GF C C
Sbjct: 352 TSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECIC 411
Query: 705 PEGYHDPTCLSEVNECNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV 763
PE + TC +VN+C C H G C+D +NGY+C C G+ G +C++ +EC S+PC
Sbjct: 412 PEQWVGATCQLDVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCH 470
Query: 764 NGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTG 823
+GG C+D+ G+ C C +GFSGP C+ +++ C +PC N C + Y C C + G
Sbjct: 471 SGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGG 530
Query: 824 ATCEVVLAPCAPSPCRNGGECRQ----------------------SEDYESFSCVCPTGW 861
C V PC CR C S+ +FSC+C +G+
Sbjct: 531 KNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF 590
Query: 862 QGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS 921
G C +I++C+ PCR+G +C + +RC C +G+ G C+T+ +DC P+PCH+ G
Sbjct: 591 TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGR 650
Query: 922 CTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCE 981
C D +N +C C G++G C +C + C NG C D D++ C CP G+ G C
Sbjct: 651 CYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCA 710
Query: 982 -NNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGC 1040
C + C NGGTCV SF+C+C G+ G C H+ N+C+ PC +GG C DG
Sbjct: 711 VAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGV 770
Query: 1041 GSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVS 1100
+RC C G+ GP+C+ + C SSPC G C YRC CP G G C
Sbjct: 771 NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC------ 824
Query: 1101 CEVAAQRQGVDVARLC-------QHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP 1153
++ + R C HG V+ N+ CRC G C + C P
Sbjct: 825 ------QEVIGFGRSCWSRGTPFPHGSSWVEDCNS--CRCLDGRRD--CSKV--WCGWKP 872
Query: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-DECLSHPCQNGGTC 1198
C S +C G C E+ +CL PC+ G C
Sbjct: 873 C----LLAGQPEALSAQCPLGQ---RCLEKAPGQCLRPPCEAWGEC 911
Score = 480 bits (1235), Expect = e-135
Identities = 258/723 (35%), Positives = 363/723 (50%), Gaps = 70/723 (9%)
Query: 106 CLTNPCRNGGTCDLL---TLTEYKCRCPPGWSGKSCQQADPCASNP-CANGGQCLPFEAS 161
C C+ G C+LL +CRC GW G+ C D C P C +G P++
Sbjct: 240 CKEAVCKQG--CNLLHGGCTVPGECRCSYGWQGRFC---DECVPYPGCVHGSCVEPWQ-- 292
Query: 162 YICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHN-EVGSYRCVCRATHTGPNCERPYV 220
C+C ++ G C +D+N CG C +GGTC N E YRC C ++G NCE+
Sbjct: 293 --CNCETNWGGLLCDKDLNYCGSHHP-CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEH 349
Query: 221 PCSPSPCQNGGTCR--PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT 278
C+ +PC NGG+C P+G EC C G++G C +ID+C N C GG CVD V+
Sbjct: 350 ACTSNPCANGGSCHEVPSG---FECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDG 406
Query: 279 YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDD 338
+ C CP +W G C DV++C+ CQ+GGTC + GY CVC G+ G C D+
Sbjct: 407 FECICPEQWVGATCQLDVNDCR---GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDE 463
Query: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKAI 397
CAS+ C G C D F+C CP G +G LC ++ D C +PC G+ C + G
Sbjct: 464 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYN--LEGDYY 521
Query: 398 CTCPSGYTGPACS-----------QDVDECSLGANP----------CEHAGKCINTL-GS 435
C CP + G CS + +D C A P C G+C++ G+
Sbjct: 522 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN 581
Query: 436 FECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECA 495
F C C G+TG C ++++C+ PC+N TC+D++ F+C C G+EG C+ N ++C
Sbjct: 582 FSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCL 641
Query: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT 555
PC GRC D +N+F C C G+ G C +C + C NG C D +T+ C C
Sbjct: 642 PDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACP 701
Query: 556 EGYTGTHCEV-DIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCR 613
G+ G+ C V C P+PC + G+C A+F+C+CR G+ G C N N+C+ PC
Sbjct: 702 PGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCY 761
Query: 614 HGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG-TCLDKIDGYECACEPGYTG 672
+GG C D N + C C G GP+C IN+D+C SSPC G TC+D+I+GY C+C PG G
Sbjct: 762 NGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAG 821
Query: 673 SMCNINID---EC--AGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVH 727
C I C G P +G + + N +CRC +G D S+V C PC+
Sbjct: 822 PRCQEVIGFGRSCWSRGTPFPHGSSWVEDCN--SCRCLDGRRD---CSKV-WCGWKPCLL 875
Query: 728 GACRDSLNGYKCDCDPGWSGTNC-DINNNECESNPCVNGGTC-KDMTSGYVCTCREGFSG 785
++L+ +C G C + +C PC G C + C R G
Sbjct: 876 AGQPEALSA-QCPL-----GQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLD 929
Query: 786 PNC 788
NC
Sbjct: 930 NNC 932
Score = 466 bits (1200), Expect = e-130
Identities = 257/785 (32%), Positives = 361/785 (45%), Gaps = 110/785 (14%)
Query: 580 CKDGVATFTC--LCRP--GYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTG 635
C + + TC CRP + GH+ TC N C+ G G
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHY-----------------TCDQYGNKA---CMDGWMG 237
Query: 636 PNCEINLDDCASSPCD--SGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTC 693
C+ + C+ G C + G EC C G+ G C DEC P G+C
Sbjct: 238 KECK---EAVCKQGCNLLHGGCT--VPG-ECRCSYGWQGRFC----DECVPYPGCVHGSC 287
Query: 694 EDGINGFTCRCPEGYHDPTCLSEVNECNSN-PCVHGAC--RDSLNGYKCDCDPGWSGTNC 750
+ + C C + C ++N C S+ PC +G + Y+C C G+SG NC
Sbjct: 288 ---VEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC 344
Query: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV 810
+ + C SNPC NGG+C ++ SG+ C C G+SGP C +I+ECASNPC GTC+D V
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQV 404
Query: 811 AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDI 870
G++C C + GATC++ + C C++GG C+ + + CVCP G+ G+ CE++
Sbjct: 405 DGFECICPEQWVGATCQLDVNDCR-GQCQHGGTCKDLVN--GYQCVCPRGFGGRHCELER 461
Query: 871 NECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 930
+EC SPC G C++ G+ CHC G+SG CE D+D C P+PC NG C + +
Sbjct: 462 DECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 521
Query: 931 CDCLPGFRGTFCEEDINECASDPCRNGANCTD--------------------CVD----S 966
C C F G C C CR C CV +
Sbjct: 522 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN 581
Query: 967 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECD 1026
++C C +GF+G +C N DC C NGGTC+D +++F C CP G+ G C + N+C
Sbjct: 582 FSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCL 641
Query: 1027 SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP 1086
PC G C D + C C G+ G C + CD+ C NGG C+ + +RC CP
Sbjct: 642 PDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACP 701
Query: 1087 SGWTGLYCDVP-SVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDL 1145
GW G C V + SC + C +GG CV +G + C C+ G+ G C
Sbjct: 702 PGWKGSTCAVAKNSSC----------LPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN 751
Query: 1146 VDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTY 1205
++C+P PC NG C D + + C+C G+ G +C IDEC S PC G TC+D N Y
Sbjct: 752 TNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGY 811
Query: 1206 KCSCPRGTQGVHCEINVD---DC---NPPVDPVSRSPKCFNNGTCVD------------- 1246
+CSCP G G C+ + C P S + N+ C+D
Sbjct: 812 RCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWK 871
Query: 1247 ------QVGGYSCTCPPGFVGERC-EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH 1299
Q S CP +G+RC E +CL PC+A G + + C R+GH
Sbjct: 872 PCLLAGQPEALSAQCP---LGQRCLEKAPGQCLRPPCEAWG-ECGAEEPPSTPCLPRSGH 927
Query: 1300 TGRRC 1304
C
Sbjct: 928 LDNNC 932
Score = 449 bits (1154), Expect = e-125
Identities = 247/772 (31%), Positives = 369/772 (47%), Gaps = 73/772 (9%)
Query: 345 FHGATCH-------DRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAI 397
++ ATC+ D + C+ + + + C C +G N
Sbjct: 202 YYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGE 261
Query: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECV 457
C C G+ G C DEC + C H G C+ ++C C + G C+ D+N C
Sbjct: 262 CRCSYGWQGRFC----DEC-VPYPGCVH-GSCVEP---WQCNCETNWGGLLCDKDLNYCG 312
Query: 458 SN-PCQNDATCLD-QIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCE 515
S+ PC N TC++ + +++C C GY G +CE C S+PC + G C + + F+C
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECH 372
Query: 516 CPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC 575
CP+G++G C D+DECAS PC G C+D + + C+C E + G C++D+++C
Sbjct: 373 CPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQ 432
Query: 576 HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTG 635
H G+CKD V + C+C G+ G HCE +EC+S PC GG C+D + + C C +G +G
Sbjct: 433 HGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSG 492
Query: 636 PNCEINLDDCASSPCDSGTCLDKIDG-YECACEPGYTGSMCNINIDECAGNPCH------ 688
P CE+++D C SPC +G ++G Y CAC + G C++ + C G C
Sbjct: 493 PLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCG 552
Query: 689 ------NGGTCEDGING------------FTCRCPEGYHDPTCLSEVNECNSNPCVH-GA 729
GT G+ G F+C C G+ C +++C PC + G
Sbjct: 553 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 612
Query: 730 CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ 789
C D ++ ++C C GW G CD N N+C +PC + G C D+ + + C C +G+ G C
Sbjct: 613 CIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH 672
Query: 790 TNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVL-APCAPSPCRNGGECRQSE 848
+ +C + C N GTC D ++C C + G+TC V + C P+PC NGG C S
Sbjct: 673 SREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG 732
Query: 849 DYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI 908
SFSC+C GW+G+TC + N+C PC +G C + +RC C G++G +C +I
Sbjct: 733 --ASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINI 790
Query: 909 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDI---NECAS--DPCRNGANCTDC 963
D+C+ +PC G +C D IN C C PG G C+E I C S P +G++ +
Sbjct: 791 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVE- 849
Query: 964 VDSYTCTCPAG---FSGIHCE------NNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT 1014
D +C C G S + C P+ + C G C++ CL PP
Sbjct: 850 -DCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPG-QCLRPPCEA 907
Query: 1015 GSYCQHDVNECDSQPCL-HGGTCQDGCGSY-----RCTCPQGYT-GPNCQNL 1059
C E S PCL G + C R PQG T G C +
Sbjct: 908 WGEC--GAEEPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQGTTVGAICSGI 957
Score = 442 bits (1137), Expect = e-123
Identities = 236/713 (33%), Positives = 328/713 (46%), Gaps = 136/713 (19%)
Query: 320 NCVCVNGWTGEDCSENI-----------------------------DDCAS-AACFHGA- 348
N C++GW G++C E + D+C C HG+
Sbjct: 228 NKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSC 287
Query: 349 ----------------------------------TCHDRVASFY-CECPHGRTGLLCH-L 372
TC + Y C CP G +G C
Sbjct: 288 VEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKA 347
Query: 373 NDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINT 432
AC SNPC G +C P + C CPSG++GP C+ D+DEC+ +NPC G C++
Sbjct: 348 EHACTSNPCANGGSCHEVPSGFE--CHCPSGWSGPTCALDIDECA--SNPCAAGGTCVDQ 403
Query: 433 LGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTD 492
+ FEC C + + G C++DVN+C CQ+ TC D + +QC+C G+ G HCE+ D
Sbjct: 404 VDGFECICPEQWVGATCQLDVNDC-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERD 462
Query: 493 ECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTC 552
ECASSPC G C D + F C CP GF+G LC+ DVD C +PC+NGA+C + Y C
Sbjct: 463 ECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYC 522
Query: 553 VCTEGYTGTHCEVDIDEC-------------DPDPCHYGSCKDGV------------ATF 587
C + + G +C V + C D P G+ GV F
Sbjct: 523 ACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNF 582
Query: 588 TCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCAS 647
+C+C G+TG +C NI++C QPCR+GGTC D +A+ CFC G G C+ N +DC
Sbjct: 583 SCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 642
Query: 648 SPCDS-GTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPE 706
PC S G C D ++ + CAC+ G+ G C+ +C C NGGTC D + F C CP
Sbjct: 643 DPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPP 702
Query: 707 GYHDPTC-LSEVNECNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVN 764
G+ TC +++ + C NPCV+ G C S + C C GW G C N N+C PC N
Sbjct: 703 GWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYN 762
Query: 765 GGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGA 824
GG C D + + C C GF+GP+C+ NI+EC S+PC TC+D++ GY+C+C G
Sbjct: 763 GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGP 822
Query: 825 TCEVVLA--------------------PCAPSPCRNGGE-----------CRQSEDYESF 853
C+ V+ C C +G C + E+
Sbjct: 823 RCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEAL 882
Query: 854 SCVCPTGWQGQTC-EVDINECVLSPCRHGASC-QNTHGGYRCHCQAGYSGRNC 904
S CP GQ C E +C+ PC C C ++G+ NC
Sbjct: 883 SAQCPL---GQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNC 932
Score = 434 bits (1116), Expect = e-121
Identities = 245/773 (31%), Positives = 348/773 (45%), Gaps = 106/773 (13%)
Query: 129 CPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGL 188
C GW GK C++A +GG +P E C C + G C +EC PG
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGE----CRCSYGWQGRFC----DECVPYPG- 281
Query: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPG 248
C HG +C P+ +C C
Sbjct: 282 CVHG---------------------SCVEPW----------------------QCNCETN 298
Query: 249 FTGQNCEENIDDCPGNN-CKNGGACVDGV-NTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
+ G C+++++ C ++ C NGG C++ + Y C CP ++G+ C + C N C
Sbjct: 299 WGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACT--SNPC 356
Query: 307 QNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRT 366
NGG+CH G+ C C +GW+G C+ +ID+CAS C G TC D+V F C CP
Sbjct: 357 ANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWV 416
Query: 367 GLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHA 426
G C L+ C G C + VNG C CP G+ G C + DEC+ ++PC
Sbjct: 417 GATCQLDVNDCRGQCQHGGTC-KDLVNGYQ-CVCPRGFGGRHCELERDECA--SSPCHSG 472
Query: 427 GKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVH 486
G C + F C C QG++GP CE+DV+ C +PC+N A C + G++ C C + G +
Sbjct: 473 GLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKN 532
Query: 487 CEVNTDEC-----------------------ASSPCLHNGRCLDKI-NEFQCECPTGFTG 522
C V + C AS C +GRC+ + F C C +GFTG
Sbjct: 533 CSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTG 592
Query: 523 HLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCH-YGSCK 581
C ++D+C PC+NG C+D + + C C G+ G C+ + ++C PDPCH G C
Sbjct: 593 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCY 652
Query: 582 DGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI- 640
D V F C C G+ G C + +C + C +GGTC D + + C C G G C +
Sbjct: 653 DLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVA 712
Query: 641 NLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGING 699
C +PC + GTC+ + C C G+ G C N ++C PC+NGG C DG+N
Sbjct: 713 KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNW 772
Query: 700 FTCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECE 758
F C C G+ P C ++EC S+PC +GA C D +NGY+C C PG +G C
Sbjct: 773 FRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGR 832
Query: 759 SNPCVNGGTCKDMTSGYV-----CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGY 813
S C + GT S +V C C +G + C PCL G +
Sbjct: 833 S--CWSRGTPFPHGSSWVEDCNSCRCLDG----RRDCSKVWCGWKPCLLAGQ--PEALSA 884
Query: 814 KCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTC 866
+C P E C PC GEC +E+ S C+ +G C
Sbjct: 885 QC----PLGQRCLEKAPGQCLRPPCEAWGEC-GAEEPPSTPCLPRSGHLDNNC 932
Score = 418 bits (1075), Expect = e-116
Identities = 224/688 (32%), Positives = 320/688 (46%), Gaps = 78/688 (11%)
Query: 46 CVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNA 105
C C + G C + C+ P G+C V + C+C + G LC L+
Sbjct: 262 CRCSYGWQGRFCDE---CVPYPGCVHGSC-------VEPWQCNCETNWGGLLCDKDLNYC 311
Query: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQAD-PCASNPCANGGQCLPFEASYIC 164
+PC NGGTC +Y+C CP G+SG++C++A+ C SNPCANGG C + + C
Sbjct: 312 GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC 371
Query: 165 HCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSP 224
HCP + GPTC D++EC P C GGTC ++V + C+C G C+ C
Sbjct: 372 HCPSGWSGPTCALDIDECASNP--CAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCR- 428
Query: 225 SPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCP 284
CQ+GGTC+ + ++C C GF G++CE D+C + C +GG C D + ++C CP
Sbjct: 429 GQCQHGGTCKDLVN-GYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCP 487
Query: 285 PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAAC 344
++G C DVD C+ P+ C+NG C+N G Y C C + + G++CS + C AC
Sbjct: 488 QGFSGPLCEVDVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGAC 545
Query: 345 F------------------------HGATCHDRVASFYCECPHGRTGLLCHLN-DACISN 379
HG +F C C G TG CH N D C+
Sbjct: 546 RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQ 605
Query: 380 PCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQ 439
PC G C + V+ C CPSG+ G C + ++C +PC G+C + + F C
Sbjct: 606 PCRNGGTC-IDEVDAFR-CFCPSGWEGELCDTNPNDCL--PDPCHSRGRCYDLVNDFYCA 661
Query: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEV-NTDECASSP 498
C G+ G C +C + C N TC D F+C C PG++G C V C +P
Sbjct: 662 CDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP 721
Query: 499 CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGY 558
C++ G C+ F C C G+ G C ++ ++C PC NG C+DG N + C C G+
Sbjct: 722 CVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 781
Query: 559 TGTHCEVDIDECDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNI---NECSSQ--PC 612
G C ++IDEC PC YG +C D + + C C PG G C+ I C S+ P
Sbjct: 782 AGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPF 841
Query: 613 RHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTG 672
HG + + N+ C CL G DC+ C CL A +P
Sbjct: 842 PHGSSWVEDCNS--CRCLDGRR---------DCSKVWCGWKPCL-------LAGQPEALS 883
Query: 673 SMCNIN-------IDECAGNPCHNGGTC 693
+ C + +C PC G C
Sbjct: 884 AQCPLGQRCLEKAPGQCLRPPCEAWGEC 911
Score = 392 bits (1008), Expect = e-108
Identities = 255/813 (31%), Positives = 338/813 (41%), Gaps = 152/813 (18%)
Query: 844 CRQSEDYES-FSC------VCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGY----R 892
CR D+ ++C C GW G+ C+ + C+ G C HGG
Sbjct: 211 CRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAV-------CKQG--CNLLHGGCTVPGE 261
Query: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
C C G+ GR C D+C P P GSC + C+C + G C++D+N C S
Sbjct: 262 CRCSYGWQGRFC----DECVPYPGCVHGSCVEPWQ---CNCETNWGGLLCDKDLNYCGSH 314
Query: 953 -PCRNGANCTDCV-DSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCP 1010
PC NG C + D Y CTCP G+SG +CE CT + C NGG+C + + F C CP
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374
Query: 1011 PGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKN 1070
G++G C D++EC S PC GGTC D + C CP+ + G CQ V+ C C++
Sbjct: 375 SGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQH 433
Query: 1071 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1130
GG C Y+C CP G+ G +C++ C + C GGLC D + H
Sbjct: 434 GGTCKDLVNGYQCVCPRGFGGRHCELERDECASSP----------CHSGGLCEDLADGFH 483
Query: 1131 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDEC--- 1187
C C G++G CE VD C PSPC+NGA C + G Y C C + G NCS + C
Sbjct: 484 CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGG 543
Query: 1188 --------------------LSHPCQNGGTCLDLPN-TYKCSCPRGTQGVHCEINVDDCN 1226
S C G C+ P + C C G G +C N+DDC
Sbjct: 544 ACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC- 602
Query: 1227 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQ 1286
C N GTC+D+V + C CP G+ GE C+ + N+CL +PC +RG C
Sbjct: 603 -------LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRG--RCYD 653
Query: 1287 RVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTC--------------------AVAS 1326
VNDF+C C G G+ C S C C NGGTC AVA
Sbjct: 654 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 713
Query: 1327 NTA----------------RGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 1370
N++ F C C G+EG TC ++ C L C NGG C+ G
Sbjct: 714 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 773
Query: 1371 TCLCLGPFTGPECQFP----ASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCH 1426
C C F GP+C+ SSPC G C E YRC CP G C
Sbjct: 774 RCECAPGFAGPDCRINIDECQSSPCAYGATC--------VDEINGYRCSCPPGRAGPRCQ 825
Query: 1427 ILDYSFGGGA-GRDIPPP---LIEEACELPECQEDAGNKVCS-LQCNNHACGWDGGDCSL 1481
+ FG R P P E C C + G + CS + C C G +L
Sbjct: 826 EV-IGFGRSCWSRGTPFPHGSSWVEDCNSCRCLD--GRRDCSKVWCGWKPCLLAGQPEAL 882
Query: 1482 NFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFS 1541
+ C +C + QC C G +C E P +
Sbjct: 883 S-----AQCPLGQRCLE-----KAPGQCLRPPCEAWG-ECGAEEPPSTPCLPR------- 924
Query: 1542 DGHCDQGCNSAECEWDGLDCAEHVPERLAAGTL 1574
GH D C ++ +HVP+ G +
Sbjct: 925 SGHLDNNCARLTLHFN----RDHVPQGTTVGAI 953
Score = 355 bits (911), Expect = 3e-97
Identities = 190/594 (31%), Positives = 270/594 (45%), Gaps = 78/594 (13%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
C NGG C C C + GP C D + C S PC GTC VD+ V + C C
Sbjct: 356 CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC--VDQ--VDGFECIC 411
Query: 90 ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP 148
+ G C LD C++GGTC L + Y+C CP G+ G+ C+ + D CAS+P
Sbjct: 412 PEQWVGATC--QLDVNDCRGQCQHGGTCKDL-VNGYQCVCPRGFGGRHCELERDECASSP 468
Query: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
C +GG C + CHCP F GP C DV+ C +P CR+G C+N G Y C C
Sbjct: 469 CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLC--EPSPCRNGARCYNLEGDYYCACPD 526
Query: 209 THTGPNCERPYVPCSPSPCQ-----------------NGGTCRPTGDVTHE------CAC 245
G NC P PC C+ G C P G + C C
Sbjct: 527 DFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCIC 586
Query: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNA 305
GFTG C ENIDDC G C+NGG C+D V+ + C CP W G+ C + ++C +P+
Sbjct: 587 DSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDC--LPDP 644
Query: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGR 365
C + G C++ + C C +GW G+ C C + C +G TC+D +F C CP G
Sbjct: 645 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW 704
Query: 366 TGLLCHL--NDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPC 423
G C + N +C+ NPC G C + C C G+ G C+ + ++C+ PC
Sbjct: 705 KGSTCAVAKNSSCLPNPCVNGGTCVGS--GASFSCICRDGWEGRTCTHNTNDCN--PLPC 760
Query: 424 EHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE 483
+ G C++ + F C+C G+ GP C I+++EC S+PC ATC+D+I ++C C PG
Sbjct: 761 YNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRA 820
Query: 484 GVHCEVN--------------------TDECASSPCLHNGRCLDKI-------------N 510
G C+ ++C S CL R K+
Sbjct: 821 GPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPE 880
Query: 511 EFQCECPTGFTGHLCQYDVDECASTPCKNGAKC-LDGPNTYTCVCTEGYTGTHC 563
+CP G + +C PC+ +C + P + C+ G+ +C
Sbjct: 881 ALSAQCPLG--QRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNC 932
Score = 164 bits (414), Expect = 1e-39
Identities = 93/265 (35%), Positives = 126/265 (47%), Gaps = 21/265 (7%)
Query: 28 GETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYA 86
G+ C NGG C C C + G C +PN CL PC + G C+ + V D+
Sbjct: 604 GQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL----VNDFY 659
Query: 87 CSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA--DPC 144
C+C G+ G C + + C C NGGTC + ++C CPPGW G +C A C
Sbjct: 660 CACDDGWKGKTCHS-REFQCDAYTCSNGGTC-YDSGDTFRCACPPGWKGSTCAVAKNSSC 717
Query: 145 ASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRC 204
NPC NGG C+ AS+ C C + G TC + N+C P C +GG C + V +RC
Sbjct: 718 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLP--CYNGGICVDGVNWFRC 775
Query: 205 VCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVT-HECACLPGFTGQNCEENID---D 260
C GP+C C SPC G TC ++ + C+C PG G C+E I
Sbjct: 776 ECAPGFAGPDCRINIDECQSSPCAYGATC--VDEINGYRCSCPPGRAGPRCQEVIGFGRS 833
Query: 261 C--PGNNCKNGGACVDGVNTYNCRC 283
C G +G + V+ N +CRC
Sbjct: 834 CWSRGTPFPHGSSWVEDCN--SCRC 856
Score = 110 bits (274), Expect = 2e-23
Identities = 78/250 (31%), Positives = 107/250 (42%), Gaps = 27/250 (10%)
Query: 30 TCLNGGKCEAANGTEACVCGGAFVGPRC--QDPNPCLSTPCKNAGTCHVVDRRGVADYAC 87
TC NGG C + T C C + G C + CL PC N GTC A ++C
Sbjct: 682 TCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTC----VGSGASFSC 737
Query: 88 SCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCAS 146
C G+ G C T N C PC NGG C + + ++C C PG++G C+ D C S
Sbjct: 738 ICRDGWEGRTC-THNTNDCNPLPCYNGGIC-VDGVNWFRCECAPGFAGPDCRINIDECQS 795
Query: 147 NPCANGGQCLPFEASYICHCPPSFHGPTCRQDV---NECGQKPGLCRHGGTCHNEVGSYR 203
+PCA G C+ Y C CPP GP C++ + C + HG + + S
Sbjct: 796 SPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNS-- 853
Query: 204 CVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNC-EENIDDCP 262
CR +C + V C PC G +P ++ +C GQ C E+ C
Sbjct: 854 --CRCLDGRRDCSK--VWCGWKPCLLAG--QPEA-LSAQCP-----LGQRCLEKAPGQCL 901
Query: 263 GNNCKNGGAC 272
C+ G C
Sbjct: 902 RPPCEAWGEC 911
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 464 bits (1195), Expect = e-130
Identities = 248/657 (37%), Positives = 321/657 (48%), Gaps = 55/657 (8%)
Query: 796 ASNPCLNQGTCIDDVA----GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYE 851
A PCLN G CIDD Y C+CL +TG C + + CA PC+NGG C +
Sbjct: 274 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTC--THGIN 331
Query: 852 SFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDC 911
SF C CP G+ G TCE + C C+HG CQ +G C CQAGY+G CE D+DDC
Sbjct: 332 SFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDC 391
Query: 912 RPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINE----CASDPCRNGANCTDCVDSY 967
P+PC NGGSC D + C C F+G CE + C S PC NG C D Y
Sbjct: 392 SPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGY 451
Query: 968 TCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE--C 1025
C CP GF G+ C PD E C NGG C+ G N+ C CP GF G C+ ++ C
Sbjct: 452 VCECPEGFMGLDCRERVPDDCE--CRNGGRCL-GANTTLCQCPLGFFGLLCEFEITAMPC 508
Query: 1026 D-SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCE 1084
+ + C GG C + GSY C C + + +L CDS PC NGG C Y CE
Sbjct: 509 NMNTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPCDSDPCFNGGSCDAHDDSYTCE 566
Query: 1085 CPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE- 1143
CP G+ G +C+ R + + C++GG C +AG +HC C +TG +CE
Sbjct: 567 CPRGFHGKHCE---------KARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEI 617
Query: 1144 DLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPN 1203
D C+ PC NG TC Y+G Y C C G+ G +C C PC NGGTC D
Sbjct: 618 GKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDT 677
Query: 1204 TYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC---------- 1253
+ C C G G C+ VD C PP + V + FN GT + V Y+C
Sbjct: 678 DFFCHCQAGYMGRRCQAEVD-CGPP-EEVKHATLRFN-GTRLGAVALYACDRGYSLSAPS 734
Query: 1254 ---TCPPGFVGERCEG--DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI 1308
C P V +++EC S PC G+ C RV + C C G+ G CE
Sbjct: 735 RIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGS--CQDRVAGYLCLCSTGYEGAHCELER 792
Query: 1309 NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPR 1368
+ C+ PC+NGG+C N ++C+CPAGF G CE + C S C +GG C SG
Sbjct: 793 DECRAHPCRNGGSCR---NLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
Query: 1369 SPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
+ C+C F G C+ S PC +PC +G C ++ S + C C + G C
Sbjct: 850 AYLCVCPESFFGYHCE-TVSDPCF-SSPCGGRGYCLASNGS--HSCTCKVGYTGEDC 902
Score = 444 bits (1141), Expect = e-124
Identities = 222/645 (34%), Positives = 310/645 (48%), Gaps = 82/645 (12%)
Query: 525 CQYDVDEC-ASTPCKNGAKCLD----GPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG- 578
C + C A PC NG KC+D G +YTC C G+TG C +D++EC PC G
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 579 SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
+C G+ +F C C G+ G CET + C ++ C+HGG CQ + + +C C G TG C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 639 EINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINI----DECAGNPCHNGGTC 693
E+++DDC+ PC + G+C+D + Y C C + G C D C PCHNGGTC
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 694 EDGINGFTCRCPEGYHDPTCLSEV-NECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDI 752
D G+ C CPEG+ C V ++C C +G N C C G+ G C+
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTTLCQCPLGFFGLLCEF 501
Query: 753 N---------------------------------------NNECESNPCVNGGTCKDMTS 773
+ C+S+PC NGG+C
Sbjct: 502 EITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD 561
Query: 774 GYVCTCREGFSGPNCQ-TNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP 832
Y C C GF G +C+ + C+S PC N GTC + Y C+C +TG CE+
Sbjct: 562 SYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD 621
Query: 833 -CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGY 891
CA PC NGG C + C CP G+ G+ CE+ + C SPC +G +C++ +
Sbjct: 622 SCASGPCHNGGTCFHY--IGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
Query: 892 RCHCQAGYSGRNCETDIDDCRPNPCHNG-----GSCTDGINTAFCD-------------C 933
CHCQAGY GR C+ ++D P + G+ + CD C
Sbjct: 680 FCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVC 739
Query: 934 LPGFRGTFCEE----DINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTE 989
P G + E +I+EC S PC +G +C D V Y C C G+ G HCE +C
Sbjct: 740 QP--HGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA 797
Query: 990 SSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQ 1049
C NGG+C + ++ C CP GF G +C+ +V+ CDS PC HGG C+ G G+Y C CP+
Sbjct: 798 HPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPE 857
Query: 1050 GYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 1094
+ G +C+ + C SSPC G C ++ + C C G+TG C
Sbjct: 858 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 436 bits (1122), Expect = e-121
Identities = 219/646 (33%), Positives = 319/646 (49%), Gaps = 53/646 (8%)
Query: 226 PCQNGGTCRP---TGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCR 282
PC NGG C TG+ ++ C+CL GFTG+ C ++++C C+NGG C G+N++ C+
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
Query: 283 CPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA 342
CP + G C C CQ+GG C +G CVC G+TG C ++DDC+
Sbjct: 337 CPAGFGGPTCETAQSPCDT--KECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPD 394
Query: 343 ACFHGATCHDRVASFYCECPHGRTGLLCHLND-----ACISNPCNEGSNCDTNPVNGKAI 397
C +G +C D V ++ C C GL C D AC+S PC+ G C + +
Sbjct: 395 PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVD--ADQGYV 452
Query: 398 CTCPSGYTGPACSQDV-DECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNEC 456
C CP G+ G C + V D+C C + G+C+ + CQC G+ G CE ++
Sbjct: 453 CECPEGFMGLDCRERVPDDCE-----CRNGGRCLGANTTL-CQCPLGFFGLLCEFEITAM 506
Query: 457 VSN---PCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513
N C + C++ G + C+C + H + C S PC + G C + +
Sbjct: 507 PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSP--CDSDPCFNGGSCDAHDDSYT 564
Query: 514 CECPTGFTGHLCQYDVDE-CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDI-DECD 571
CECP GF G C+ C+S PC+NG C + Y C C +TG HCE+ D C
Sbjct: 565 CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCA 624
Query: 572 PDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCL 630
PCH G +C + + C C PG++G HCE + C PC +GGTC+DRD + C C
Sbjct: 625 SGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ 684
Query: 631 KGTTGPNCEINLDDCASSPCD------SGTCLDKIDGYECACEPGYTGS------MCN-- 676
G G C+ +D +GT L + Y AC+ GY+ S +C
Sbjct: 685 AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALY--ACDRGYSLSAPSRIRVCQPH 742
Query: 677 ---------INIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVH 727
+ IDEC PC +GG+C+D + G+ C C GY C E +EC ++PC +
Sbjct: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRN 802
Query: 728 G-ACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGP 786
G +CR+ Y C C G+ G +C+ + C+S+PC +GG C+ Y+C C E F G
Sbjct: 803 GGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGY 862
Query: 787 NCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP 832
+C+T + C S+PC +G C+ + C C + YTG C L P
Sbjct: 863 HCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
Score = 433 bits (1114), Expect = e-121
Identities = 228/644 (35%), Positives = 312/644 (48%), Gaps = 80/644 (12%)
Query: 487 CEVNTDEC-ASSPCLHNGRCLDKI----NEFQCECPTGFTGHLCQYDVDECASTPCKNGA 541
C T C A PCL+ G+C+D + C C +GFTG C DV+ECAS PC+NG
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 542 KCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHC 600
C G N++ C C G+ G CE CD C H G C+ + C+C+ GYTG C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEIN----LDDCASSPC-DSGTC 655
E ++++CS PC +GG+C D Y C C + G CE D C S+PC + GTC
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 656 LDKIDGYECACEPGYTGSMCNINI-DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCL 714
+D GY C C G+ G C + D+C C NGG C G N C+CP G+ C
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCL-GANTTLCQCPLGFFGLLCE 500
Query: 715 SEV---------------------------------------NECNSNPCVHG-ACRDSL 734
E+ + C+S+PC +G +C
Sbjct: 501 FEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHD 560
Query: 735 NGYKCDCDPGWSGTNCD-INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI- 792
+ Y C+C G+ G +C+ + C S PC NGGTCK+ Y C+C F+G +C+
Sbjct: 561 DSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKP 620
Query: 793 NECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYES 852
+ CAS PC N GTC + YKC+C ++G CE+ +PC SPC NGG C +
Sbjct: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDT--D 678
Query: 853 FSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTH--GGYRCH-CQAGYSG------RN 903
F C C G+ G+ C+ +++ +H N G + C GYS R
Sbjct: 679 FFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRV 738
Query: 904 CET-----------DIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
C+ +ID+CR PC +GGSC D + C C G+ G CE + +EC +
Sbjct: 739 CQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAH 798
Query: 953 PCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1012
PCRNG +C + +Y C CPAGF G+HCE C S C +GG C G ++ C+CP
Sbjct: 799 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPES 858
Query: 1013 FTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 1056
F G +C+ + C S PC G C GS+ CTC GYTG +C
Sbjct: 859 FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 427 bits (1097), Expect = e-119
Identities = 222/638 (34%), Positives = 285/638 (44%), Gaps = 106/638 (16%)
Query: 761 PCVNGGTC-KDMTSG---YVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
PC+NGG C D +G Y C+C GF+G C ++NECAS PC N GTC + ++C
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
Query: 817 CLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLS 876
C + G TCE +PC C++GG+C+ S CVC G+ G CE+D+++C
Sbjct: 337 CPAGFGGPTCETAQSPCDTKECQHGGQCQVENG--SAVCVCQAGYTGAACEMDVDDCSPD 394
Query: 877 PCRHGASCQNTHGGYRCHCQAGYSGRNCETDI----DDCRPNPCHNGGSCTD-------- 924
PC +G SC + G Y C C + G CET D C PCHNGG+C D
Sbjct: 395 PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCE 454
Query: 925 ---------------------------GINTAFCDCLPGFRGTFCEEDI----------- 946
G NT C C GF G CE +I
Sbjct: 455 CPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQC 514
Query: 947 ----------------------------NECASDPCRNGANCTDCVDSYTCTCPAGFSGI 978
+ C SDPC NG +C DSYTC CP GF G
Sbjct: 515 PDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGK 574
Query: 979 HCENNTPD-CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ-HDVNECDSQPCLHGGTC 1036
HCE P C+ C NGGTC + + C CP FTG +C+ + C S PC +GGTC
Sbjct: 575 HCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC 634
Query: 1037 QDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC-- 1094
G Y+C CP G++G +C+ C SPC NGG C T + C C +G+ G C
Sbjct: 635 FHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQA 694
Query: 1095 --------DVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLV 1146
+V + R G C G C+ ++ +
Sbjct: 695 EVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEI 754
Query: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206
DEC PC +G +C D + GY C C GY G +C E DEC +HPC+NGG+C +LP Y
Sbjct: 755 DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV 814
Query: 1207 CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG 1266
C CP G GVHCE VD C+ S C + G C G Y C CP F G CE
Sbjct: 815 CRCPAGFVGVHCETEVDACD--------SSPCQHGGRCESGGGAYLCVCPESFFGYHCET 866
Query: 1267 DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRC 1304
+ C S+PC RG C+ C C+ G+TG C
Sbjct: 867 VSDPCFSSPCGGRG--YCLASNGSHSCTCKVGYTGEDC 902
Score = 424 bits (1091), Expect = e-118
Identities = 217/644 (33%), Positives = 304/644 (47%), Gaps = 72/644 (11%)
Query: 449 CEIDVNECVS-NPCQNDATCLDQI----GEFQCICMPGYEGVHCEVNTDECASSPCLHNG 503
C + C++ PC N C+D + C C+ G+ G C ++ +ECAS PC + G
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 504 RCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHC 563
C IN F+C+CP GF G C+ C + C++G +C + CVC GYTG C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 564 EVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINE----CSSQPCRHGGTC 618
E+D+D+C PDPC + GSC D V +TCLC + G CET + C S PC +GGTC
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 619 QDRDNAYLCFCLKGTTGPNCEINL-DDC-------------------------------A 646
D D Y+C C +G G +C + DDC
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT 504
Query: 647 SSPC-------DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGING 699
+ PC D G C++ Y C C + S + C +PC NGG+C+ +
Sbjct: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS--HSLPSPCDSDPCFNGGSCDAHDDS 562
Query: 700 FTCRCPEGYHDPTC-LSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINN-NE 756
+TC CP G+H C + + C+S PC +G C+++ Y C C ++G +C+I +
Sbjct: 563 YTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDS 622
Query: 757 CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
C S PC NGGTC Y C C GFSG +C+ + C +PC+N GTC D + C+
Sbjct: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCH 682
Query: 817 CLLPYTGATCEVVLAPCAPSPCR------NGGECRQSEDY---ESFSCVCPTG------- 860
C Y G C+ + P + NG Y +S P+
Sbjct: 683 CQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
Query: 861 --WQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHN 918
W ++I+EC PC HG SCQ+ GY C C GY G +CE + D+CR +PC N
Sbjct: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRN 802
Query: 919 GGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGI 978
GGSC + C C GF G CE +++ C S PC++G C +Y C CP F G
Sbjct: 803 GGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGY 862
Query: 979 HCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDV 1022
HCE + C S C G C+ S +C C G+TG C ++
Sbjct: 863 HCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 415 bits (1067), Expect = e-115
Identities = 238/652 (36%), Positives = 301/652 (46%), Gaps = 53/652 (8%)
Query: 104 NACLT-NPCRNGGTC--DLLTLT-EYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPF 158
+ CL PC NGG C D +T Y C C G++G+ C + CAS PC NGG C
Sbjct: 270 SVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHG 329
Query: 159 EASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERP 218
S+ C CP F GPTC + C K C+HGG C E GS CVC+A +TG CE
Sbjct: 330 INSFRCQCPAGFGGPTCETAQSPCDTKE--CQHGGQCQVENGSAVCVCQAGYTGAACEMD 387
Query: 219 YVPCSPSPCQNGGTCRP-TGDVTHECACLPGFTGQNCEEN----IDDCPGNNCKNGGACV 273
CSP PC NGG+C G+ T C C F G CE D C C NGG CV
Sbjct: 388 VDDCSPDPCLNGGSCVDLVGNYT--CLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCV 445
Query: 274 DGVNTYNCRCPPEWTGQYCTEDV-DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDC 332
D Y C CP + G C E V D+C+ C+NGG C + C C G+ G C
Sbjct: 446 DADQGYVCECPEGFMGLDCRERVPDDCE-----CRNGGRCLGANTTL-CQCPLGFFGLLC 499
Query: 333 SENIDDC---ASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDT 389
I + C G C + S+ C C H L C S+PC G +CD
Sbjct: 500 EFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC-HTDHNASHSLPSPCDSDPCFNGGSCDA 558
Query: 390 NPVNGKAICTCPSGYTGPACSQDVDE-CSLGANPCEHAGKCINTLGSFECQCLQGYTGPR 448
+ + C CP G+ G C + CS G PC + G C G + C C +TG
Sbjct: 559 H--DDSYTCECPRGFHGKHCEKARPHLCSSG--PCRNGGTCKEAGGEYHCSCPYRFTGRH 614
Query: 449 CEI-DVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLD 507
CEI + C S PC N TC IG+++C C PG+ G HCE+ C SPC++ G C D
Sbjct: 615 CEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCED 674
Query: 508 KINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN---TYTCVCTEGYT----- 559
+ +F C C G+ G CQ +VD K+ +G C GY+
Sbjct: 675 RDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPS 734
Query: 560 --------GTHCE----VDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINE 606
G E ++IDEC PC H GSC+D VA + CLC GY G HCE +E
Sbjct: 735 RIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDE 794
Query: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD-SGTCLDKIDGYECA 665
C + PCR+GG+C++ AY+C C G G +CE +D C SSPC G C Y C
Sbjct: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCV 854
Query: 666 CEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEV 717
C + G C D C +PC G C +C C GY C E+
Sbjct: 855 CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 401 bits (1030), Expect = e-111
Identities = 210/646 (32%), Positives = 291/646 (45%), Gaps = 120/646 (18%)
Query: 646 ASSPC-DSGTCLDKI----DGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF 700
A PC + G C+D Y C+C G+TG C+++++ECA PC NGGTC GIN F
Sbjct: 274 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSF 333
Query: 701 TCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECES 759
C+CP G+ PTC + + C++ C HG C+ C C G++G C+++ ++C
Sbjct: 334 RCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSP 393
Query: 760 NPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE----CASNPCLNQGTCIDDVAGYK- 814
+PC+NGG+C D+ Y C C E F G C+T + C S PC N GTC+D GY
Sbjct: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
Query: 815 ----------------------------------CNCLLPYTGATCEVVL---------- 830
C C L + G CE +
Sbjct: 454 ECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQ 513
Query: 831 -----------------------------APCAPSPCRNGGECRQSEDYESFSCVCPTGW 861
+PC PC NGG C +D S++C CP G+
Sbjct: 514 CPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD--SYTCECPRGF 571
Query: 862 QGQTCE-VDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI-DDCRPNPCHNG 919
G+ CE + C PCR+G +C+ G Y C C ++GR+CE D C PCHNG
Sbjct: 572 HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNG 631
Query: 920 GSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIH 979
G+C I CDC PGF G CE + C PC NG C D + C C AG+ G
Sbjct: 632 GTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRR 691
Query: 980 CENNTPDC------TESSCFNGGTCVDGINSFTC-------------LCPPGFTGSYCQH 1020
C+ DC ++ GT + + + C +C P S
Sbjct: 692 CQAEV-DCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQ 750
Query: 1021 --DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH 1078
+++EC SQPCLHGG+CQD Y C C GY G +C+ C + PC+NGG C
Sbjct: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLP 810
Query: 1079 TQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
Y C CP+G+ G++C+ +C+ + CQHGG C G + C C +
Sbjct: 811 GAYVCRCPAGFVGVHCETEVDACDSSP----------CQHGGRCESGGGAYLCVCPESFF 860
Query: 1139 GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
G +CE + D C SPC C G +SC C GY G +C++E+
Sbjct: 861 GYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 370 bits (951), Expect = e-102
Identities = 207/582 (35%), Positives = 277/582 (47%), Gaps = 53/582 (9%)
Query: 21 GPRCS---QPGET--CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTC 74
GP C P +T C +GG+C+ NG+ CVC + G C+ D + C PC N G+C
Sbjct: 343 GPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSC 402
Query: 75 HVVDRRGVADYACSCALGFSGPLCLT---PLDNACLTNPCRNGGTCDLLTLTEYKCRCPP 131
VD V +Y C CA F G C T P+ +ACL+ PC NGGTC + Y C CP
Sbjct: 403 --VDL--VGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC-VDADQGYVCECPE 457
Query: 132 GWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN--ECGQKPGLC 189
G+ G C++ P C NGG+CL + +C CP F G C ++ C C
Sbjct: 458 GFMGLDCRERVP-DDCECRNGGRCLGANTT-LCQCPLGFFGLLCEFEITAMPCNMNT-QC 514
Query: 190 RHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF 249
GG C GSY CVC H + PC PC NGG+C D ++ C C GF
Sbjct: 515 PDGGYCMEHGGSYLCVCHTDHNASHSLPS--PCDSDPCFNGGSC-DAHDDSYTCECPRGF 571
Query: 250 TGQNCEENIDD-CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC-TEDVDECQLMPNACQ 307
G++CE+ C C+NGG C + Y+C CP +TG++C D C P C
Sbjct: 572 HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGP--CH 629
Query: 308 NGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTG 367
NGGTC + G Y C C G++G C C + C +G TC DR F+C C G G
Sbjct: 630 NGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG 689
Query: 368 LLCHLNDACISNPCNEGSNCDTNPVNGK-----AICTCPSGYTGPACSQ----------- 411
C C P E + T NG A+ C GY+ A S+
Sbjct: 690 RRCQAEVDC--GPPEEVKHA-TLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWS 746
Query: 412 ------DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDA 465
++DEC + PC H G C + + + C C GY G CE++ +EC ++PC+N
Sbjct: 747 EPPQCLEIDECR--SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGG 804
Query: 466 TCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLC 525
+C + G + C C G+ GVHCE D C SSPC H GRC + C CP F G+ C
Sbjct: 805 SCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHC 864
Query: 526 QYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDI 567
+ D C S+PC CL +++C C GYTG C ++
Sbjct: 865 ETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 311 bits (798), Expect = 4e-84
Identities = 205/663 (30%), Positives = 270/663 (40%), Gaps = 136/663 (20%)
Query: 942 CEEDINEC-ASDPCRNGANCTD-CVD---SYTCTCPAGFSGIHCENNTPDCTESSCFNGG 996
C + C A PC NG C D CV SYTC+C +GF+G C + +C C NGG
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 997 TCVDGINSFTCLCPPGF--------------------------------------TGSYC 1018
TC GINSF C CP GF TG+ C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 1019 QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVH----WCDSSPCKNGGKC 1074
+ DV++C PCL+GG+C D G+Y C C + + G C+ H C S+PC NGG C
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 1075 WQTHTQYRCECPSGWTGLYC--DVP--------------------------SVSCEVAAQ 1106
Y CECP G+ GL C VP + CE
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT 504
Query: 1107 RQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGG 1166
++ C GG C++ G ++ C C + S+ L C PC NG +C +
Sbjct: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPCDSDPCFNGGSCDAHDDS 562
Query: 1167 YSCKCVAGYHGVNCSEEIDE-CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDC 1225
Y+C+C G+HG +C + C S PC+NGGTC + Y CSCP G HCEI D
Sbjct: 563 YTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDS 622
Query: 1226 NPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCV 1285
S C N GTC +G Y C CPPGF G CE + C +PC GT C
Sbjct: 623 -------CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT--CE 673
Query: 1286 QRVNDFHCECRAGHTGRRCESVINGCKGKPCK------NGGTCAVASNTA--RGFICKCP 1337
R DF C C+AG+ GRRC++ ++ + K NG + A RG+ P
Sbjct: 674 DRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAP 733
Query: 1338 AGF-----EGATCEN----DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPAS 1388
+ G E + C S CL+GG+C CLC + G C+
Sbjct: 734 SRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERD 793
Query: 1389 SPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC-------------HILDYSFGGG 1435
+PC N G+C + Y C CPA F G+ C H GGG
Sbjct: 794 E--CRAHPCRNGGSCRNLPGA--YVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
Query: 1436 AGRDIPP--------PLIEEACELPECQEDAGNKVCSLQCNNHAC----GWDGGDCSLNF 1483
A + P + + C C G C +H+C G+ G DC+
Sbjct: 850 AYLCVCPESFFGYHCETVSDPCFSSPC---GGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Query: 1484 NDP 1486
P
Sbjct: 907 FPP 909
Score = 125 bits (314), Expect = 5e-28
Identities = 70/193 (36%), Positives = 95/193 (49%), Gaps = 10/193 (5%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGP-RCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
C G A + C G + P +C + + C S PC + G+C DR VA Y C C
Sbjct: 724 CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQ--DR--VAGYLCLC 779
Query: 90 ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP 148
+ G+ G C D C +PCRNGG+C L Y CRCP G+ G C+ + D C S+P
Sbjct: 780 STGYEGAHCELERDE-CRAHPCRNGGSCRNLP-GAYVCRCPAGFVGVHCETEVDACDSSP 837
Query: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
C +GG+C +Y+C CP SF G C + C P C G C GS+ C C+
Sbjct: 838 CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSP--CGGRGYCLASNGSHSCTCKV 895
Query: 209 THTGPNCERPYVP 221
+TG +C + P
Sbjct: 896 GYTGEDCAKELFP 908
Score = 51.2 bits (121), Expect = 1e-05
Identities = 21/34 (61%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Query: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
CS +PCQNGGTC P D H C C PGF G+ CE
Sbjct: 1311 CSENPCQNGGTCVPGAD-AHSCDCGPGFKGRRCE 1343
Score = 49.3 bits (116), Expect = 5e-05
Identities = 18/34 (52%), Positives = 22/34 (64%)
Query: 910 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCE 943
+C NPC NGG+C G + CDC PGF+G CE
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 48.9 bits (115), Expect = 6e-05
Identities = 58/221 (26%), Positives = 78/221 (35%), Gaps = 60/221 (27%)
Query: 1388 SSPCLGGNPCYNQGTC--EPTSESPFYRCLCPAKFNGLLCHI------------------ 1427
+S CL PC N G C + + +P Y C C + F G CH+
Sbjct: 269 TSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTH 328
Query: 1428 --------LDYSFGGGAGRDIPPPLIEEACEL-PECQEDAGNKVCSLQC--NNHACGWDG 1476
FGG P + C+ +CQ + G+ VC Q AC D
Sbjct: 329 GINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDV 388
Query: 1477 GDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCL----FDGFDCQRAEGQCNPLY 1532
DCS DP N G C + CL F G C+ + +P+
Sbjct: 389 DDCS---PDPCLN------------GGSCVDLVGNYTCLCAEPFKGLRCETGD---HPVP 430
Query: 1533 DQY----CKDHFSDGHCDQG--CNSAECEWDGLDCAEHVPE 1567
D C + + DQG C E + GLDC E VP+
Sbjct: 431 DACLSAPCHNGGTCVDADQGYVCECPE-GFMGLDCRERVPD 470
Score = 46.6 bits (109), Expect = 3e-04
Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Query: 983 NTP-DCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ 1019
N P +C+E+ C NGGTCV G ++ +C C PGF G C+
Sbjct: 1306 NVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 45.4 bits (106), Expect = 7e-04
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA---NGGQCLPFEASY 162
C NPC+NGGTC + + C C PG+ G+ C+ A S PC + + P
Sbjct: 1311 CSENPCQNGGTC-VPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
Query: 163 ICH 165
+CH
Sbjct: 1370 VCH 1372
Score = 43.5 bits (101), Expect = 0.003
Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 3/52 (5%)
Query: 751 DINN--NECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPC 800
DI N C NPC NGGTC + C C GF G C+ + S PC
Sbjct: 1303 DIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 43.1 bits (100), Expect = 0.003
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Query: 1187 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF---NNGT 1243
C +PCQNGGTC+ + + C C G +G CE+ + P + K F G
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 1244 C 1244
C
Sbjct: 1371 C 1371
Score = 42.7 bits (99), Expect = 0.005
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 13/68 (19%)
Query: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQY-----------CTEDVDECQLMPNACQN 308
+C N C+NGG CV G + ++C C P + G+ CT E + P
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFP--VWE 1367
Query: 309 GGTCHNTH 316
GG CH+ +
Sbjct: 1368 GGVCHHVY 1375
Score = 42.7 bits (99), Expect = 0.005
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 144 CASNPCANGGQCLPFEASYICHCPPSFHGPTC 175
C+ NPC NGG C+P ++ C C P F G C
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 42.4 bits (98), Expect = 0.006
Identities = 14/33 (42%), Positives = 20/33 (60%)
Query: 949 CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCE 981
C+ +PC+NG C D+++C C GF G CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 41.6 bits (96), Expect = 0.010
Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 11/61 (18%)
Query: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVN-----------CSEEIDECLSHPCQNGGT 1197
CS +PCQNG TC +SC C G+ G C+ E + P GG
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 1198 C 1198
C
Sbjct: 1371 C 1371
Score = 41.6 bits (96), Expect = 0.010
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPC 499
C NPCQN TC+ C C PG++G CE+ + S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 41.6 bits (96), Expect = 0.010
Identities = 13/34 (38%), Positives = 21/34 (61%)
Query: 532 CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV 565
C+ PC+NG C+ G + ++C C G+ G CE+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 41.2 bits (95), Expect = 0.013
Identities = 16/28 (57%), Positives = 17/28 (60%)
Query: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
C N GTCV +SC C PGF G RCE
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 39.7 bits (91), Expect = 0.038
Identities = 13/33 (39%), Positives = 18/33 (54%)
Query: 1025 CDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
C PC +GGTC G ++ C C G+ G C+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 39.7 bits (91), Expect = 0.038
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC 713
C+ NPC NGGTC G + +C C G+ C
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 38.9 bits (89), Expect = 0.066
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 1299 HTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
H + +V C PC+NGGTC A C C GF+G CE
Sbjct: 1299 HGSKDIGNVPGNCSENPCQNGGTCVPG---ADAHSCDCGPGFKGRRCE 1343
Score = 38.9 bits (89), Expect = 0.066
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 11/61 (18%)
Query: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEV----VLAPCA-------PSPCRNGGE 843
C+ NPC N GTC+ + C+C + G CE+ V PC P GG
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 844 C 844
C
Sbjct: 1371 C 1371
Score = 38.9 bits (89), Expect = 0.066
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPC 461
NPC++ G C+ + C C G+ G RCE+ + VS PC
Sbjct: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 38.5 bits (88), Expect = 0.086
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 12/61 (19%)
Query: 720 CNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDIN-----------NNECESNPCVNGGT 767
C+ NPC +G C + + CDC PG+ G C++ +E ++ P GG
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 768 C 768
C
Sbjct: 1371 C 1371
Score = 38.5 bits (88), Expect = 0.086
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI 640
CS PC++GGTC +A+ C C G G CE+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 38.1 bits (87), Expect = 0.11
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 12/62 (19%)
Query: 644 DCASSPCDSG-TCLDKIDGYECACEPGYTGSMCNIN-----------IDECAGNPCHNGG 691
+C+ +PC +G TC+ D + C C PG+ G C + E P GG
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
Query: 692 TC 693
C
Sbjct: 1370 VC 1371
Score = 37.7 bits (86), Expect = 0.15
Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEV 868
C+ +PC+NGG C D + SC C G++G+ CE+
Sbjct: 1311 CSENPCQNGGTCVPGAD--AHSCDCGPGFKGRRCEL 1344
Score = 37.0 bits (84), Expect = 0.25
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 14/74 (18%)
Query: 1261 GERCEGDV-NECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE-----------SVI 1308
G + G+V C NPC GT CV + C+C G GRRCE +
Sbjct: 1300 GSKDIGNVPGNCSENPCQNGGT--CVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLF 1357
Query: 1309 NGCKGKPCKNGGTC 1322
+ K P GG C
Sbjct: 1358 SETKAFPVWEGGVC 1371
Score = 37.0 bits (84), Expect = 0.25
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143
CQ+GG CV + H C C G+ G CE
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 36.2 bits (82), Expect = 0.43
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 19/81 (23%)
Query: 60 PNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACL--TNPCRNGGTC 117
P C PC+N GTC G ++C C GF G C + AC+ + PC
Sbjct: 1308 PGNCSENPCQNGGTC----VPGADAHSCDCGPGFKGRRC----ELACIKVSRPC------ 1353
Query: 118 DLLTLTEYKCRCPPGWSGKSC 138
T + + P W G C
Sbjct: 1354 ---TRLFSETKAFPVWEGGVC 1371
Score = 36.2 bits (82), Expect = 0.43
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 14/69 (20%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCK------------NA 71
CS+ C NGG C +C CG F G RC+ +S PC
Sbjct: 1311 CSE--NPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEG 1368
Query: 72 GTCHVVDRR 80
G CH V +R
Sbjct: 1369 GVCHHVYKR 1377
Score = 36.2 bits (82), Expect = 0.43
Identities = 12/37 (32%), Positives = 20/37 (54%)
Query: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSV 1099
C +PC+NGG C + C+C G+ G C++ +
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACI 1347
Score = 35.4 bits (80), Expect = 0.73
Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPC 537
C+ +PC + G C+ + C+C GF G C+ + S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 35.0 bits (79), Expect = 0.95
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCE 905
C +PC++G +C + C C G+ GR CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 34.7 bits (78), Expect = 1.2
Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 3/43 (6%)
Query: 1352 CGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQ---FPASSPC 1391
C C NGGTC+ G + +C C F G C+ S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 34.3 bits (77), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 570 CDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQPC 612
C +PC G +C G +C C PG+ G CE + S+PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
Score = 32.7 bits (73), Expect = 4.7
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 304 NACQNGGTCHNTHGGYNCVCVNGWTGEDC 332
N CQNGGTC ++C C G+ G C
Sbjct: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 32.3 bits (72), Expect = 6.1
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 338 DCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPC 381
+C+ C +G TC + C+C G G C L +S PC
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 436 bits (1122), Expect = e-121
Identities = 452/1585 (28%), Positives = 592/1585 (37%), Gaps = 381/1585 (24%)
Query: 128 RCPPGW----SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECG 183
RC GW + C A+ C+++ C +GG+C+P A CHCPP F GP C+ DV+EC
Sbjct: 109 RCCRGWMQQPDEEGCLSAE-CSASLCFHGGRCVPGSAQP-CHCPPGFQGPRCQYDVDECR 166
Query: 184 QKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGT---CRPTGDVT 240
G C+H C N GSY C C+ R + + NGG C
Sbjct: 167 THNGGCQH--RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITR 224
Query: 241 HECACLPGF----TGQNCEENIDDCPGNN--CKNGGACVDGVNTYNCRCPPEWT--GQYC 292
H C C PGF G++C C N C + V G+ C + G+ C
Sbjct: 225 HRCQCRPGFQLQEDGRHCVRR-SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKAC 283
Query: 293 TEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW----TGEDC----SENIDDCA--SA 342
EDVDEC C +G C NT G + CVC G+ G C E ++ C +
Sbjct: 284 -EDVDECAAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNG 340
Query: 343 ACFHGATCHDRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAIC 398
C HG C A C CP G C D C +PC + C NP G C
Sbjct: 341 GCSHG--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNP--GGYEC 395
Query: 399 TCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY---------- 444
C +GY G C +DVDEC+ CEH C N GSF+C C GY
Sbjct: 396 GCYAGYRLSADGCGC-EDVDECASSRGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCS 452
Query: 445 --TGPRCEIDVNECVSNPCQNDATCLDQIGEF-----------------------QCICM 479
P ++D P + A D++ + + +C+
Sbjct: 453 PLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCL 512
Query: 480 PGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQ-------YDVDEC 532
G C + D+C + G CL ++ C+CP G+TG +C + +
Sbjct: 513 DDSFGHDCSLTCDDCR-----NGGTCLLGLD--GCDCPEGWTGLICNETCPPDTFGKNCS 565
Query: 533 ASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCR 592
S C+NG C T C C G +GT+CE DG C
Sbjct: 566 FSCSCQNGGTC--DSVTGACRCPPGVSGTNCE-----------------DG-------CP 599
Query: 593 PGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDS 652
GY G HC N C + G C A C C G G C + A P S
Sbjct: 600 KGYYGKHCRKKCN------CANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCS 651
Query: 653 GTC---------LDKIDGYECACEPGYTGSMCNINIDECA----GNPCHNGGTCE----- 694
C DK DG C+C+ G+ G C EC G C TC
Sbjct: 652 EECQCVQPHTQSCDKRDG-SCSCKAGFRGERCQA---ECELGYFGPGCWQACTCPVGVAC 707
Query: 695 DGINGFTC--RCPEGYHDPTCLSEVN------ECNSNPCVHGACRDSLNGYKCDCDPGWS 746
D ++G C RCP G+ C E C+S+ GA + G +C C PG +
Sbjct: 708 DSVSG-ECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG-QCRCPPGRT 765
Query: 747 GTNCDINNNE------CES--NPCVNGGTCKDMTSGYVC-----------TCREGFSGPN 787
G +C+ + E C+ C + C T +C C G+ GP+
Sbjct: 766 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS 825
Query: 788 CQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVL-----APCAPSPCRNGG 842
CQT + C N G C A C+C +TG +C+ P PC N
Sbjct: 826 CQTRCS------CANDGHC--HPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC-NCS 876
Query: 843 ECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP-------CRHGASCQNTHGGYRCHC 895
S D S C+C G+ G CE + P C+HGA+C + G C C
Sbjct: 877 AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA--CTC 934
Query: 896 QAGYSGRNCETDID------DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDI--- 946
AG+ G CE DCR G+ D +N + C C G RG C E
Sbjct: 935 PAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS-CLCPAGRRGPRCAETCPAH 993
Query: 947 ----NECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTP------DCTESS-CFNG 995
N + C NGA+C D V C C G+ G C P +C S C NG
Sbjct: 994 TYGHNCSQACACFNGASC-DPVHG-QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNG 1051
Query: 996 GTCVDGINSFTCLCPPGFTGSYCQHDVNECD-------SQPCLHGGTCQDGCGSYRCTCP 1048
GTC D ++ C CP G+ G C+ + D S CL+GG C G RC CP
Sbjct: 1052 GTC-DPVSGH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCP 1107
Query: 1049 QGYTGPNCQN--LVHW-----CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC 1101
G+TG CQ+ L W C G C H C CP G+TG C+ +C
Sbjct: 1108 AGWTGDKCQSPCLRGWFGEACAQRCSCPPGAAC--HHVTGACRCPPGFTGSGCE---QAC 1162
Query: 1102 EVAAQRQGVDVARLCQHGG---LCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGA 1158
+ G D A++CQ G C A T C C AGY G C+
Sbjct: 1163 PPGS--FGEDCAQMCQCPGENPACHPATGT--CSCAAGYHGPSCQQ-------------- 1204
Query: 1159 TCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHC 1218
+C G +G C E++ CL NGG+C T C CP G G C
Sbjct: 1205 -----------RCPPGRYGPGC-EQLCGCL-----NGGSC--DAATGACRCPTGFLGTDC 1245
Query: 1219 EINVDDCNPPVDPVSR-SPKCFN-----NGTCVDQVGGYSCTCPPGFVGERCEGDVNE-- 1270
+ P R P C + G D V G +C CPPG G RCE +
Sbjct: 1246 NLTC--------PQGRFGPNCTHVCGCGQGAACDPVTG-TCLCPPGRAGVRCERGCPQNR 1296
Query: 1271 ---CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE-SVINGCKGK------PCKNGG 1320
+ C R C ++ C C G TGR CE + G G C N
Sbjct: 1297 FGVGCEHTCSCRNGGLC--HASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS 1354
Query: 1321 TCAVASNTAR------GFICK--CPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTC 1372
TC A+ T R G C+ CP GF GA C+ G C +G C P S C
Sbjct: 1355 TCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQ------GLCWCQHGAPC--DPISGRC 1406
Query: 1373 LCLGPFTGPECQFPASSPCLGGNPCYNQGTCE--PTSESPFYRCLCPAKFNGLLCHILDY 1430
LC F G C+ P G C+ + C+ + CLCP +G C++
Sbjct: 1407 LCPAGFHGHFCE-RGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNL--- 1462
Query: 1431 SFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNC 1490
+C+ C+L C+ CG G DC DP
Sbjct: 1463 ----------------------DCRRGQFGPSCTLHCD---CG-GGADC-----DP---- 1487
Query: 1491 TQSLQCWKYFSDGHCDSQCNSAGCL 1515
S QC + DG+ C G L
Sbjct: 1488 -VSGQC--HCVDGYMGPTCREGGPL 1509
Score = 412 bits (1060), Expect = e-114
Identities = 427/1537 (27%), Positives = 570/1537 (37%), Gaps = 340/1537 (22%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCH-VVDRRGVADYACS 88
C +GG+C + C C F GPRCQ D + C + N G H V+ G Y C
Sbjct: 133 CFHGGRC-VPGSAQPCHCPPGFQGPRCQYDVDECRT---HNGGCQHRCVNTPG--SYLCE 186
Query: 89 CALGFSGPLCLTPLDNACLT-NPCR--NGGT---CDLLTLTEYKCRCPPGW----SGKSC 138
C GF L CL N C NGG C LT+T ++C+C PG+ G+ C
Sbjct: 187 CKPGFR----LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 242
Query: 139 QQADPCASNPCANGGQCLPFEASYICHCPPSFH----GPTCRQDVNECGQKPGLCRHGGT 194
+ PCA+ + +C C C + G C +DV+EC C HG
Sbjct: 243 VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKAC-EDVDECAAGLAQCAHG-- 299
Query: 195 CHNEVGSYRCVCRATH----TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHE---CACLP 247
C N GS++CVC A + G C R + S N G C T C C
Sbjct: 300 CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPR 359
Query: 248 GF---TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEW--TGQYC-TEDVDECQL 301
G+ T Q ++DDC + C C + Y C C + + C EDVDEC
Sbjct: 360 GYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS 418
Query: 302 MPNACQNGGTCHNTHGGYNCVCVNGWTGED----CS---ENIDDCASAACF-----HGAT 349
C++ C N G + C C G+ + CS E + D F H A
Sbjct: 419 SRGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAV 476
Query: 350 CHDRVASFY-------------CECPHGRTGLLCHLND------ACISNPCNEGSNCDTN 390
D + + H T L+D + + C G C
Sbjct: 477 LQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTC--- 533
Query: 391 PVNGKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGSFECQ------ 439
+ G C CP G+TG C++ + G N C++ G C + G+ C
Sbjct: 534 -LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGT 592
Query: 440 -----CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDEC 494
C +GY G C N C N C G C+C PG G C +
Sbjct: 593 NCEDGCPKGYYGKHCRKKCN------CANRGRCHRLYG--ACLCDPGLYGRFCHLTCPPW 644
Query: 495 ASSP-CLHNGRCL-------DKINEFQCECPTGFTGHLCQYDVD---------------- 530
A P C +C+ DK + C C GF G CQ + +
Sbjct: 645 AFGPGCSEECQCVQPHTQSCDK-RDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPV 703
Query: 531 --ECASTPCKNGAKCLDGPNTYTC--VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVAT 586
C S + G +C G C C G G +C C PCH GV T
Sbjct: 704 GVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSC-SCGGAPCH------GV-T 755
Query: 587 FTCLCRPGYTGHHCETNINE------CSS--QPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
C C PG TG CE + E C C+H C A C CL G G C
Sbjct: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRC 813
Query: 639 EINLDDCAS---SPCDSGTCLDKIDGY------ECACEPGYTGSMCNINID------ECA 683
+ D C + P C DG+ C+C PG+TG C D +C+
Sbjct: 814 Q---DVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCS 870
Query: 684 GNPCH---NGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNP-------CVHGACRDS 733
+PC+ G+C D I+G C C GY P C + + + P C HGA D
Sbjct: 871 -HPCNCSAGHGSC-DAISGL-CLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDH 927
Query: 734 LNGYKCDCDPGWSGTNCD------INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPN 787
++G C C GW GT C+ +C S G D +G C C G GP
Sbjct: 928 VSG-ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNG-SCLCPAGRRGPR 985
Query: 788 C------QTNINECA-SNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPS---- 836
C T + C+ + C N +C D V G +C+C + G +C L C
Sbjct: 986 CAETCPAHTYGHNCSQACACFNGASC-DPVHG-QCHCAPGWMGPSC---LQACPAGLYGD 1040
Query: 837 ------PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVD-INECVLSPCRHGASCQN--- 886
C+NGG C D S C CP GW G CE + + V + CRH C N
Sbjct: 1041 NCRHSCLCQNGGTC----DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGL 1096
Query: 887 --THGGYRCHCQAGYSGRNCETD-IDDCRPNPCHNGGSCTDGIN----TAFCDCLPGFRG 939
H G RC C AG++G C++ + C SC G T C C PGF G
Sbjct: 1097 CDPHTG-RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTG 1155
Query: 940 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCV 999
+ CE+ C G+ DC + C CP C T C+ ++ ++G +C
Sbjct: 1156 SGCEQ--------ACPPGSFGEDC--AQMCQCPG--ENPACHPATGTCSCAAGYHGPSCQ 1203
Query: 1000 DGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRC-----------TCP 1048
CPPG G C+ CL+GG+C G+ RC TCP
Sbjct: 1204 Q-------RCPPGRYGPGCEQLCG------CLNGGSCDAATGACRCPTGFLGTDCNLTCP 1250
Query: 1049 QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQ 1108
QG GPNC H C C G C C CP G G+ C+ C
Sbjct: 1251 QGRFGPNC---THVCG---CGQGAAC--DPVTGTCLCPPGRAGVRCE---RGCPQNRFGV 1299
Query: 1109 GVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD----------ECSPSPCQNGA 1158
G + C++GGLC + + C C G+TG +CE ECS C N +
Sbjct: 1300 GCEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECS---CHNNS 1354
Query: 1159 TCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ---NGGTCLDL----------PNTY 1205
TC G +C+C G++G C HPC +G C L P +
Sbjct: 1355 TCEPATG--TCRCGPGFYGQAC--------EHPCPPGFHGAGCQGLCWCQHGAPCDPISG 1404
Query: 1206 KCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC-FNNGTCVDQVGGYSCTCPPGFVGERC 1264
+C CP G G CE C P +C + G D V G C CPPG G C
Sbjct: 1405 RCLCPAGFHGHFCE---RGCEPGSFGEGCHQRCDCDGGAPCDPVTGL-CLCPPGRSGATC 1460
Query: 1265 EGDVNECLSNP-----CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNG 1319
D P CD G +C HC ++G G C+ G
Sbjct: 1461 NLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHC--------------VDGYMGPTCREG 1506
Query: 1320 GTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR 1356
G + N + + + AG A+ +R+ G R
Sbjct: 1507 GPLRLPENPS---LAQGSAGTLPASSRPTSRSGGPAR 1540
Score = 371 bits (953), Expect = e-102
Identities = 384/1413 (27%), Positives = 513/1413 (36%), Gaps = 279/1413 (19%)
Query: 282 RCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCAS 341
RC W Q E + + C +GG C C C G+ G C ++D+C +
Sbjct: 109 RCCRGWMQQPDEEGCLSAECSASLCFHGGRCV-PGSAQPCHCPPGFQGPRCQYDVDECRT 167
Query: 342 --AACFHGATCHDRVASFYCECPHGRTGLLCHLND-ACIS-NPCNEGSN-CDTNPVN--- 393
C H C + S+ CEC + G H + C++ N C G+ C + V
Sbjct: 168 HNGGCQH--RCVNTPGSYLCEC---KPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTI 222
Query: 394 GKAICTCPSGYTGPACSQDVDECSLGANPCEHA-GKCINTL----GSFECQCLQGYT--- 445
+ C C G+ +D C + +PC + G C++ G C+C GY
Sbjct: 223 TRHRCQCRPGFQ---LQEDGRHC-VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAA 278
Query: 446 -GPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE----GVHCEVNTDECASSPCL 500
G CE DV+EC + Q CL+ G F+C+C GYE G C E +S
Sbjct: 279 DGKACE-DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA 337
Query: 501 HNGRCLDKINEFQ----CECPTGF---TGHLCQYDVDECASTPCKNGAKCLDGPNTYTCV 553
+NG C + C CP G+ T DVD+CA +PC C + P Y C
Sbjct: 338 NNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQV-CTNNPGGYECG 396
Query: 554 CTEGYT----GTHCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETNINEC 607
C GY G CE D+DEC C + C + +F C C GY H +
Sbjct: 397 CYAGYRLSADGCGCE-DVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGCSPL 454
Query: 608 SS------------QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTC 655
+P H QD G E+ + + + C
Sbjct: 455 EEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLT---EKFVC 511
Query: 656 LDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLS 715
LD G++C+ + D+C NGGTC G++G C CPEG+ C
Sbjct: 512 LDDSFGHDCS-----------LTCDDC-----RNGGTCLLGLDG--CDCPEGWTGLIC-- 551
Query: 716 EVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGY 775
NE C P G NC S C NGGTC +T
Sbjct: 552 --NET--------------------CPPDTFGKNCSF------SCSCQNGGTCDSVTGA- 582
Query: 776 VCTCREGFSGPNCQTNI------NECASN-PCLNQGTCIDDVAGYKCNCLLPYTGATCEV 828
C C G SG NC+ C C N+G C C C G C +
Sbjct: 583 -CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA--CLCDPGLYGRFCHL 639
Query: 829 VLAPCAPSP-CRNGGEC----RQSEDYESFSCVCPTGWQGQTCEVDINECVLSP------ 877
P A P C +C QS D SC C G++G+ C+ + P
Sbjct: 640 TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQAC 699
Query: 878 -CRHGASCQNTHGGYRCHCQAGYSGRNCETDID------DCRPNPCHNGGSCTDGINTAF 930
C G +C + G C AG+ G +C + +C + C GG+ G+ T
Sbjct: 700 TCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSS-CSCGGAPCHGV-TGQ 757
Query: 931 CDCLPGFRGTFCEEDINE------CAS--DPCRNGANCTDCVDSYTCTCPAGFSGIHCEN 982
C C PG G CE D E C C++ A C ++ C C GF G C++
Sbjct: 758 CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDP--ETGACLCLPGFVGSRCQD 815
Query: 983 NTP------DC-TESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDS----QPCL 1031
P C T SC N G C C C PG+TG CQ CD+ C
Sbjct: 816 VCPAGWYGPSCQTRCSCANDGHCHPATGH--CSCAPGWTGFSCQR---ACDTGHWGPDCS 870
Query: 1032 HGGTCQDGCGSYR-----CTCPQGYTGPNCQNLVHWCDSSP-------CKNGGKCWQTHT 1079
H C G GS C C GY GP C+ P C++G C H
Sbjct: 871 HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAAC--DHV 928
Query: 1080 QYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTG 1139
C CP+GW G +C+ +C A C G C DA N C C AG G
Sbjct: 929 SGACTCPAGWRGTFCEH---ACPAGFFGLDCRSACNCTAGAAC-DAVNGS-CLCPAGRRG 983
Query: 1140 SYCEDLVD------ECSPS-PCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI------DE 1186
C + CS + C NGA+C G C C G+ G +C + D
Sbjct: 984 PRCAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDN 1041
Query: 1187 CL-SHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVS--RSPKCFNNGT 1243
C S CQNGGTC P + C+CP G G+ CE +C P S C N G
Sbjct: 1042 CRHSCLCQNGGTCD--PVSGHCACPEGWAGLACE---KECLPRDVRAGCRHSGGCLNGGL 1096
Query: 1244 CVDQVGGYSCTCPPGFVGERCE-----GDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
C G C CP G+ G++C+ G E + C C C C G
Sbjct: 1097 CDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPG 1152
Query: 1299 HTGRRCESVIN-GCKGKPCKNGGTCA---VASNTARGFICKCPAGFEGATCENDA----- 1349
TG CE G G+ C C A + A G C C AG+ G +C+
Sbjct: 1153 FTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATG-TCSCAAGYHGPSCQQRCPPGRY 1211
Query: 1350 -----RTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGN-----PCYN 1399
+ CG CLNGG+C + + C C F G +C G N C
Sbjct: 1212 GPGCEQLCG---CLNGGSCDAA--TGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQ 1266
Query: 1400 QGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 1459
C+P + + CLCP G+ C R P CE
Sbjct: 1267 GAACDPVTGT----CLCPPGRAGVRCE-----------RGCPQNRFGVGCE--------- 1302
Query: 1460 NKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGF 1519
CS + N C G CS ++C + +Y + H + C+ +
Sbjct: 1303 -HTCSCR-NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH------NNS 1354
Query: 1520 DCQRAEGQCN---PLYDQYCKDHFSDGHCDQGC 1549
C+ A G C Y Q C+ G GC
Sbjct: 1355 TCEPATGTCRCGPGFYGQACEHPCPPGFHGAGC 1387
Score = 255 bits (651), Expect = 4e-67
Identities = 257/880 (29%), Positives = 318/880 (36%), Gaps = 232/880 (26%)
Query: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRR 80
G C + C + +C+ G AC+C FVG RCQD
Sbjct: 779 GLGCQEICPACQHAARCDPETG--ACLCLPGFVGSRCQDV-------------------- 816
Query: 81 GVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ 140
C G+ GP C T C N G C T C C PGW+G SCQ+
Sbjct: 817 --------CPAGWYGPSCQTRCS-------CANDGHCHPAT---GHCSCAPGWTGFSCQR 858
Query: 141 A------DPCASNPC---ANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGL--- 188
A P S+PC A G C S +C C + GP C Q + PG
Sbjct: 859 ACDTGHWGPDCSHPCNCSAGHGSC--DAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR 916
Query: 189 --CRHGGTCHNEVGSYRCVCRATHTGPNCERPY------VPC-SPSPCQNGGTCRPTGDV 239
C+HG C + G+ C C A G CE + C S C G C V
Sbjct: 917 CQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC---DAV 971
Query: 240 THECACLPGFTGQNCEENIDDCP----GNNCKNGGACVDGVNT----YNCRCPPEWTGQY 291
C C G G C E CP G+NC AC +G + C C P W G
Sbjct: 972 NGSCLCPAGRRGPRCAET---CPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPS 1028
Query: 292 CTEDV------DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA----- 340
C + D C+ CQNGGTC G +C C GW G C + +C
Sbjct: 1029 CLQACPAGLYGDNCR-HSCLCQNGGTCDPVSG--HCACPEGWAGLACEK---ECLPRDVR 1082
Query: 341 -----SAACFHGATCHDRVASFYCECPHGRTGLLCH-------LNDACISN-PCNEGSNC 387
S C +G C C CP G TG C +AC C G+ C
Sbjct: 1083 AGCRHSGGCLNGGLCDPHTGR--CLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAAC 1140
Query: 388 DTNPVNGKAICTCPSGYTGPACSQDVDECSLG---ANPCEHAGK---CINTLGSFECQCL 441
+ V G C CP G+TG C Q S G A C+ G+ C G+ C C
Sbjct: 1141 --HHVTG--ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT--CSCA 1194
Query: 442 QGYTGPRCEIDVNECVSNP-------CQNDATCLDQIGEFQCICMPGYEGVHCEVNTDEC 494
GY GP C+ P C N +C G C C G+ G C + +
Sbjct: 1195 AGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG--ACRCPTGFLGTDCNLTCPQG 1252
Query: 495 ASSP-CLH-----NGRCLDKINEFQCECPTGFTGHLCQYDVDE------CAST-PCKNGA 541
P C H G D + C CP G G C+ + C T C+NG
Sbjct: 1253 RFGPNCTHVCGCGQGAACDPVTG-TCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG 1311
Query: 542 KCLDGPNTYTCVCTEGYTGTHCEVDIDECDPD----PCHYG-SCKDG----VATFTCLCR 592
C + +C C G+TG HCE+ C P CH SC + AT TC C
Sbjct: 1312 LC--HASNGSCSCGLGWTGRHCEL---ACPPGRYGAACHLECSCHNNSTCEPATGTCRCG 1366
Query: 593 PGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD- 651
PG+ G CE + C P HG CQ LC+C G +PCD
Sbjct: 1367 PGFYGQACE---HPC--PPGFHGAGCQG-----LCWCQHG---------------APCDP 1401
Query: 652 -SGTCL--DKIDGYEC--ACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPE 706
SG CL G+ C CEPG G C+ D G PC D + G C CP
Sbjct: 1402 ISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPC-------DPVTGL-CLCPP 1453
Query: 707 GYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGG 766
G TC DC G G +C ++ C+ C G
Sbjct: 1454 GRSGATC------------------------NLDCRRGQFGPSCTLH---CD---CGGGA 1483
Query: 767 TCKDMTSGYVCTCREGFSGPNC-QTNINECASNPCLNQGT 805
C D SG C C +G+ GP C + NP L QG+
Sbjct: 1484 DC-DPVSGQ-CHCVDGYMGPTCREGGPLRLPENPSLAQGS 1521
Score = 244 bits (622), Expect = 1e-63
Identities = 281/1092 (25%), Positives = 390/1092 (35%), Gaps = 259/1092 (23%)
Query: 606 ECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCAS--SPCDSGTCLDKIDGYE 663
ECS+ C HGG C +A C C G GP C+ ++D+C + C C++ Y
Sbjct: 127 ECSASLCFHGGRCVP-GSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH-RCVNTPGSYL 184
Query: 664 CACEPGY---TGSMCNINIDECA-GNPCHNGGTCEDGINGFTCRCPEGYH----DPTCLS 715
C C+PG+ T S + I+ CA GN + I C+C G+ C+
Sbjct: 185 CECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVR 244
Query: 716 EVNECNSN-PCVHGACRDSLNGYKCDCDPGWS----GTNCDINNNECESN--PCVNGGTC 768
N N C+H C+ +C+C G+ G C+ + +EC + C +G C
Sbjct: 245 RSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGLAQCAHG--C 300
Query: 769 KDMTSGYVCTCREGFS----GPNC----QTNINECASNPCLNQGTCIDDVAGYKCNCLLP 820
+ + C C G+ G C +N C +N C AG C C
Sbjct: 301 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 360
Query: 821 YTGATCE---VVLAPCAPSPCRNGGECRQ--SEDYESFSCVCPTGWQ----GQTCEVDIN 871
Y T + + + CA SPC C+Q + + + C C G++ G CE D++
Sbjct: 361 YELDTDQRTCIDVDDCADSPC-----CQQVCTNNPGGYECGCYAGYRLSADGCGCE-DVD 414
Query: 872 ECVLSP--CRHGASCQNTHGGYRCHCQAGY----SGRNCE------TDIDDCRP--NPCH 917
EC S C H C N G ++C C+AGY R C D+D P P
Sbjct: 415 ECASSRGGCEH--HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLP 472
Query: 918 NGGSCTDGINTAFCDCLPG-------FRGTF-------CEEDI--NECA--SDPCRNGAN 959
+ D + F D G RG C +D ++C+ D CRNG
Sbjct: 473 HIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGT 532
Query: 960 CTDCVDSYTCTCPAGFSGIHCENNTP------DCTES-SCFNGGTCVDGINSFTCLCPPG 1012
C +D C CP G++G+ C P +C+ S SC NGGTC D + C CPPG
Sbjct: 533 CLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC-DSVTG-ACRCPPG 588
Query: 1013 FTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1072
+G+ C+DGC P+GY G +C+ + C N G
Sbjct: 589 VSGT------------------NCEDGC-------PKGYYGKHCRKKCN------CANRG 617
Query: 1073 KCWQTHTQY-RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLC--QHGGLCVDAGNTH 1129
+C H Y C C G G +C + +C A G C H C +
Sbjct: 618 RC---HRLYGACLCDPGLYGRFCHL---TCPPWAFGPGCSEECQCVQPHTQSCDKRDGS- 670
Query: 1130 HCRCQAGYTGSYCEDLVDECS----------PSPCQNGATCTDYLGGYSCKCVAGYHGVN 1179
C C+AG+ G C+ EC C G C G +C AG+ G +
Sbjct: 671 -CSCKAGFRGERCQA---ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGED 726
Query: 1180 CSEEID------ECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVS 1233
C +E C S G C + T +C CP G G CE + + +
Sbjct: 727 CGQECPVGTFGVNCSSSCSCGGAPCHGV--TGQCRCPPGRTGEDCEADCPEGRWGLGCQE 784
Query: 1234 RSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----GDVNECLSNPCDARGTQNCVQRV 1288
P C + C + G +C C PGFVG RC+ G C +C
Sbjct: 785 ICPACQHAARCDPETG--ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPAT 842
Query: 1289 NDFHCECRAGHTGRRCESVIN-GCKGKPCKNGGTCAVASNTARGF--ICKCPAGFEGATC 1345
HC C G TG C+ + G G C + C+ + +C C AG+ G C
Sbjct: 843 G--HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRC 900
Query: 1346 ENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEP 1405
E C G P C CQ C + C+
Sbjct: 901 EQQ--------------CPQGHFGPGC-------EQRCQ------------CQHGAACDH 927
Query: 1406 TSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 1465
S + C CPA + G C E AC D C
Sbjct: 928 VSGA----CTCPAGWRGTFC--------------------EHACPAGFFGLD-----CRS 958
Query: 1466 QCN---NHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQ 1522
CN AC G C C ++ Y GH C+ A F+G C
Sbjct: 959 ACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTY---GH---NCSQACACFNGASCD 1012
Query: 1523 RAEGQCN-------PLYDQYCKDHFSDGHCDQGC---NSAECE-----------WDGLDC 1561
GQC+ P Q C +C C N C+ W GL C
Sbjct: 1013 PVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLAC 1072
Query: 1562 -AEHVPERLAAG 1572
E +P + AG
Sbjct: 1073 EKECLPRDVRAG 1084
Score = 173 bits (438), Expect = 2e-42
Identities = 160/556 (28%), Positives = 201/556 (36%), Gaps = 147/556 (26%)
Query: 13 LLPALAARGPRCSQ--PGET----------CLNGGKCEAANGTEACVCGGAFVGPRCQDP 60
L PA RGPRC++ P T C NG C+ +G C C ++GP C
Sbjct: 976 LCPA-GRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQ--CHCAPGWMGPSCLQA 1032
Query: 61 NPC--------LSTPCKNAGTC-----HVVDRRGVADYACS------------------- 88
P S C+N GTC H G A AC
Sbjct: 1033 CPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCL 1092
Query: 89 -------------CALGFSGPLCLTP-----LDNACLTN-PCRNGGTCDLLTLTEYKCRC 129
C G++G C +P AC C G C +T CRC
Sbjct: 1093 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA---CRC 1149
Query: 130 PPGWSGKSCQQADPCAS--NPCANGGQCLPFE------ASYICHCPPSFHGPTCRQDVNE 181
PPG++G C+QA P S CA QC P E A+ C C +HGP+C+Q
Sbjct: 1150 PPGFTGSGCEQACPPGSFGEDCAQMCQC-PGENPACHPATGTCSCAAGYHGPSCQQRCPP 1208
Query: 182 CGQKPGL-----CRHGGTCHNEVGSYRC-----------VCRATHTGPNCERPYVPCSPS 225
PG C +GG+C G+ RC C GPNC C
Sbjct: 1209 GRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTH---VCG-- 1263
Query: 226 PCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGN----------NCKNGGACVDG 275
C G C P VT C C PG G CE CP N +C+NGG C
Sbjct: 1264 -CGQGAACDP---VTGTCLCPPGRAGVRCERG---CPQNRFGVGCEHTCSCRNGGLC--H 1314
Query: 276 VNTYNCRCPPEWTGQYCTEDVD------ECQLMPNACQNGGTCHNTHGGYNCVCVNGWTG 329
+ +C C WTG++C C L +C N TC G C C G+ G
Sbjct: 1315 ASNGSCSCGLGWTGRHCELACPPGRYGAACHL-ECSCHNNSTCEPATG--TCRCGPGFYG 1371
Query: 330 EDCSENIDDCASAA-------CFHGATCHDRVASFYCECPHGRTGLLCH--LNDACISNP 380
+ C A C HGA C S C CP G G C
Sbjct: 1372 QACEHPCPPGFHGAGCQGLCWCQHGAPCDP--ISGRCLCPAGFHGHFCERGCEPGSFGEG 1429
Query: 381 CNEGSNCD----TNPVNGKAICTCPSGYTGPACSQDVDECSLGAN---PCEHAGKCINTL 433
C++ +CD +PV G +C CP G +G C+ D G + C+ G
Sbjct: 1430 CHQRCDCDGGAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDP 1487
Query: 434 GSFECQCLQGYTGPRC 449
S +C C+ GY GP C
Sbjct: 1488 VSGQCHCVDGYMGPTC 1503
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 370 bits (949), Expect = e-101
Identities = 176/458 (38%), Positives = 240/458 (52%), Gaps = 39/458 (8%)
Query: 332 CSENIDDCASAACFHGATCHDRVASFYCECPHGRTGL---LCHLNDACISNPCNEGSNCD 388
C++N C S +C + +TC D C C L ++ D C SNPC + C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 389 TNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPR 448
P +C CP GY+G C + C G N C+H G C C C GY G
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSC--GKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 449 CEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
CEID +EC S+PCQN A C D I + C C+PGY+G HC++ DECAS PC + CL++
Sbjct: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
Query: 509 INEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDID 568
I + C CP ++G C+ ++DEC S PC NGA C D Y C C G+ G HCE++ D
Sbjct: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
Query: 569 ECDPDPC-HYGSCKDGVATFTCLCR-PGYTGHHCETNINECSSQPCRHGGTCQDRDNAYL 626
EC PC H G C DG ++C C G+TG HCET + C S+PC + TC+D + Y
Sbjct: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYT 324
Query: 627 CFCLKGTTGPNCEINLDDCASSPCDS-GTCLD--------------------KIDGYECA 665
C C G TG CEI+L++C S+PC S G C++ + GY C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 666 CEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCP------EGYHDPTCLSEVNE 719
C+PG+TG C +++EC+ NPC NGGTCE+ +TC CP Y C +
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 720 CNSNPCV-HGAC----RDSLNGYKCDCDPGWSGTNCDI 752
C C+ +G C +D +G+ C C G++G+ C+I
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 362 bits (930), Expect = 2e-99
Identities = 173/457 (37%), Positives = 240/457 (52%), Gaps = 39/457 (8%)
Query: 600 CETNINECSSQPCRHGGTCQD--RDNAYLCFCLKGTTGPNCEINLDDCASSPCD-SGTCL 656
C N C S C++ TC+D +DN C +C+ D C S+PC S TC+
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 657 DKID--GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCL 714
+ + C C PGY+G++C I C N C +GG C C CP GY C
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 715 SEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTS 773
+ +EC S+PC +GA C+D ++GY C C PG+ G +CD+ +EC S+PC N TC +
Sbjct: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
Query: 774 GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPC 833
Y C C +SG NC+ I+EC S PCLN TC D + Y C+C + G CE+ C
Sbjct: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
Query: 834 APSPCRNGGECRQSEDYESFSCVCP-TGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
A PC +GG C E+ +SC C +G+ G CE + C PC + A+C+++ Y
Sbjct: 267 ASQPCLHGGLCVDGEN--RYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYT 324
Query: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTD-----------GINTAF---------CD 932
CHC GY+G CE D+++C NPC + G C + G+ ++F C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP------AGFSGIHCENNTPD 986
C PGF G CEED+NEC+S+PC+NG C + +YTC CP + G C +
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 987 CTESSCFNGGTCV----DGINSFTCLCPPGFTGSYCQ 1019
CT C N GTC+ DG + F+CLCP G+TGS C+
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 357 bits (917), Expect = 6e-98
Identities = 178/462 (38%), Positives = 243/462 (52%), Gaps = 44/462 (9%)
Query: 254 CEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ--LMPNACQNGGT 311
C +N C N+C+N C D +C C T +D D + N CQ T
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 312 CHNTHG--GYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLL 369
C NT G + C C G++G C I C +C HG CH C CP G G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 370 CHL-NDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGK 428
C + +D C S+PC G+ C + ++G + C C GY G C +VDEC+ ++PC++
Sbjct: 145 CEIDHDECASSPCQNGAVCQ-DGIDGYS-CFCVPGYQGRHCDLEVDECA--SDPCKNEAT 200
Query: 429 CINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCE 488
C+N +G + C C Y+G CE++++EC S PC N ATC D +G + C C PG+ G HCE
Sbjct: 201 CLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
Query: 489 VNTDECASSPCLHNGRCLDKINEFQCECP-TGFTGHLCQYDVDECASTPCKNGAKCLDGP 547
+NTDECAS PCLH G C+D N + C C +GFTG C+ + C S PC N A C D
Sbjct: 261 LNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 548 NTYTCVCTEGYTGTHCEVDIDECDPDPCH-YGSCKD--------------------GVAT 586
+ YTC C GYTG CE+D++EC+ +PC G C + +
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 587 FTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFC----LKGT--TGPNCEI 640
+ C+C+PG+TG HCE ++NECSS PC++GGTC++ Y C C L T G +C
Sbjct: 381 YVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440
Query: 641 NLDDCASSPC-DSGTCL----DKIDGYECACEPGYTGSMCNI 677
L C C ++GTC+ D G+ C C GYTGS+C I
Sbjct: 441 ILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 354 bits (908), Expect = 7e-97
Identities = 173/461 (37%), Positives = 238/461 (51%), Gaps = 40/461 (8%)
Query: 673 SMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYH--DPTCLSEVNECNSNPCVHGAC 730
S CN N C N C N TC+D C C + + D C + + C SNPC A
Sbjct: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 731 RDSLNG---YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPN 787
+ G + C C PG+SGT C+ C N C +GG C VC C G++G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 788 CQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
C+ + +ECAS+PC N C D + GY C C+ Y G C++ + CA PC+N C
Sbjct: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC--L 202
Query: 848 EDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
+ ++C+CP + G CE++I+EC PC +GA+CQ+ G Y C C G+ G +CE +
Sbjct: 203 NEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN 262
Query: 908 IDDCRPNPCHNGGSCTDGINTAFCDCL-PGFRGTFCEEDINECASDPCRNGANCTDCVDS 966
D+C PC +GG C DG N C+C GF GT CE + C S PC N A C D VD+
Sbjct: 263 TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
Query: 967 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD-----------GINS---------FT 1006
YTC C G++G CE + +C + C + G CV+ G+ S +
Sbjct: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 1007 CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCP------QGYTGPNCQNLV 1060
C+C PGFTG +C+ DVNEC S PC +GGTC++ G+Y C CP Y G +C +++
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDIL 442
Query: 1061 HWCDSSPCKNGGKCWQTHTQ-----YRCECPSGWTGLYCDV 1096
C C N G C H Q + C CPSG+TG C++
Sbjct: 443 LGCTHQQCLNNGTC-IPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 346 bits (887), Expect = 2e-94
Identities = 165/460 (35%), Positives = 232/460 (50%), Gaps = 39/460 (8%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHG--G 890
C + C+N C+ SC + C+ + C +PC+ A+C NT G
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 891 YRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECA 950
+ C C GYSG CET I C N C +GG C C C G+ G FCE D +ECA
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
Query: 951 SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCP 1010
S PC+NGA C D +D Y+C C G+ G HC+ +C C N TC++ I +TC+CP
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICP 213
Query: 1011 PGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKN 1070
++G C+ +++EC SQPCL+G TCQD G+Y C C G+ G +C+ C S PC +
Sbjct: 214 HNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLH 273
Query: 1071 GGKCWQTHTQYRCECP-SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH 1129
GG C +Y C C SG+TG +C+ C ++ C + C D+ + +
Sbjct: 274 GGLCVDGENRYSCNCTGSGFTGTHCETLMPLC----------WSKPCHNNATCEDSVDNY 323
Query: 1130 HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDY--------------------LGGYSC 1169
C C GYTG+ CE ++EC+ +PCQ+ C + GY C
Sbjct: 324 TCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383
Query: 1170 KCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV 1229
C G+ G++C E+++EC S+PCQNGGTC +LP Y C CP DC+ +
Sbjct: 384 ICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLS-RTFYGGRDCSDIL 442
Query: 1230 DPVSRSPKCFNNGTCV----DQVGGYSCTCPPGFVGERCE 1265
+ +C NNGTC+ D G+SC CP G+ G CE
Sbjct: 443 LGCTHQ-QCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 322 bits (824), Expect = 4e-87
Identities = 167/482 (34%), Positives = 223/482 (46%), Gaps = 58/482 (12%)
Query: 938 RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIH--CENNTPDCTESSCFNG 995
+ +FC ++ C S+ C+N + C D C+C + + C+N C + C
Sbjct: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
Query: 996 GTCVD--GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTG 1053
TCV+ G SF C CPPG++G+ C+ + C C HGG C C CP GY G
Sbjct: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
Query: 1054 PNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVA 1113
C+ C SSPC+NG C Y C C G+ G +CD+ C +
Sbjct: 143 RFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC----------AS 192
Query: 1114 RLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVA 1173
C++ C++ + C C Y+G CE +DEC PC NGATC D LG Y C C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAP 252
Query: 1174 GYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCP-RGTQGVHCEINVDDCNPPVDPV 1232
G+ G +C DEC S PC +GG C+D N Y C+C G G HCE + P+
Sbjct: 253 GFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM--------PL 304
Query: 1233 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQ------ 1286
S C NN TC D V Y+C C PG+ G +CE D+NEC SNPC + G CV+
Sbjct: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNG--ECVELSSEKQ 362
Query: 1287 --------------RVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGF 1332
+ + C C+ G TG CE +N C PC+NGGTC N +
Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTC---ENLPGNY 419
Query: 1333 ICKCP------AGFEGATCENDARTCGSLRCLNGGTCI----SGPRSPTCLCLGPFTGPE 1382
C CP + G C + C +CLN GTCI G +CLC +TG
Sbjct: 420 TCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSL 479
Query: 1383 CQ 1384
C+
Sbjct: 480 CE 481
Score = 319 bits (818), Expect = 2e-86
Identities = 172/478 (35%), Positives = 221/478 (46%), Gaps = 52/478 (10%)
Query: 980 CENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTG--SYCQHDVNECDSQPCLHGGTCQ 1037
C N C +SC N TC D C C C + + C S PC TC
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 1038 DGCG--SYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD 1095
+ G S+ C CP GY+G C+ + C + C++GG C Q C CP+G+ G +C+
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 1096 VPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQ 1155
+ C + CQ+G +C D + + C C GY G +C+ VDEC+ PC+
Sbjct: 147 IDHDECASSP----------CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 1156 NGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQG 1215
N ATC + +G Y+C C Y GVNC EIDEC S PC NG TC D Y C C G G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 1216 VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP-PGFVGERCEGDVNECLSN 1274
HCE+N D+C S C + G CVD YSC C GF G CE + C S
Sbjct: 257 DHCELNTDEC--------ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK 308
Query: 1275 PCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNT------ 1328
PC T C V+++ C C G+TG +CE +N C PC++ G C S+
Sbjct: 309 PCHNNAT--CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRI 366
Query: 1329 -----------ARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGP 1377
A G++C C GF G CE D C S C NGGTC + P + TC C P
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC--P 424
Query: 1378 FTGPECQFPASSPC----LG--GNPCYNQGTCEPTSESPF--YRCLCPAKFNGLLCHI 1427
F F C LG C N GTC P + + CLCP+ + G LC I
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 319 bits (818), Expect = 2e-86
Identities = 164/449 (36%), Positives = 222/449 (49%), Gaps = 42/449 (9%)
Query: 189 CRHGGTCHNEVGSYRCVCR--ATHTGPNCERPYVPCSPSPCQNGGTCRPT-GDVTHECAC 245
C++ TC + C C A + +C+ PC +PCQ TC T G+ + C C
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
Query: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNA 305
PG++G CE I C N+C++GG C C CP + G++C D DEC P
Sbjct: 99 PPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP-- 156
Query: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGR 365
CQNG C + GY+C CV G+ G C +D+CAS C + ATC + + + C CPH
Sbjct: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216
Query: 366 TGLLCHLN-DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCE 424
+G+ C L D C S PC G+ C G C C G+ G C + DEC+ + PC
Sbjct: 217 SGVNCELEIDECWSQPCLNGATC--QDALGAYFCDCAPGFLGDHCELNTDECA--SQPCL 272
Query: 425 HAGKCINTLGSFECQCL-QGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE 483
H G C++ + C C G+TG CE + C S PC N+ATC D + + C C PGY
Sbjct: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT 332
Query: 484 GVHCEVNTDECASSPCLHNGRCLDKINEFQ--------------------CECPTGFTGH 523
G CE++ +EC S+PC NG C++ +E Q C C GFTG
Sbjct: 333 GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGI 392
Query: 524 LCQYDVDECASTPCKNGAKCLDGPNTYTCVC------TEGYTGTHCEVDIDECDPDPC-H 576
C+ DV+EC+S PC+NG C + P YTC C Y G C + C C +
Sbjct: 393 HCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLN 452
Query: 577 YGSC----KDGVATFTCLCRPGYTGHHCE 601
G+C +DG F+CLC GYTG CE
Sbjct: 453 NGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 286 bits (733), Expect = 1e-76
Identities = 153/460 (33%), Positives = 207/460 (45%), Gaps = 83/460 (18%)
Query: 106 CLTNPCRNGGTC-DLLTLTEYKCRCPPGWSGKSCQQA-DPCASNPCANGGQCL--PFEAS 161
CL+N C+N TC D + C K C DPC SNPC C+ P E S
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 162 YICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP 221
++C CPP + G C + CG+ C+HGG CH + C+C A + G CE +
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNS--CQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE 151
Query: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNC 281
C+ SPCQNG C+ D + C C+PG+ G++C+ +D+C + CKN C++ + Y C
Sbjct: 152 CASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTC 210
Query: 282 RCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCAS 341
CP ++G C ++DEC P C NG TC + G Y C C G+ G+ C N D+CAS
Sbjct: 211 ICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 342 AACFHGATCHDRVASFYCECP-HGRTGLLCH-LNDACISNPCNEGSNCDTNPVNGKAICT 399
C HG C D + C C G TG C L C S PC+ + C+ + N C
Sbjct: 269 QPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN--YTCH 326
Query: 400 CPSGYTGPACSQDVDECSLGANPCEHAGKCI--------------------NTLGSFECQ 439
C GYTG C D++EC+ +NPC+ G+C+ + + C
Sbjct: 327 CWPGYTGAQCEIDLNECN--SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGE-------------------------- 473
C G+TG CE DVNEC SNPCQN TC + G
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 474 ----------------------FQCICMPGYEGVHCEVNT 491
F C+C GY G CE+ T
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIAT 484
Score = 233 bits (594), Expect = 2e-60
Identities = 137/451 (30%), Positives = 197/451 (43%), Gaps = 79/451 (17%)
Query: 30 TCLNGGKCEAANGTEACVCGGAF--VGPRCQD-PNPCLSTPCKNAGTCHVVDRRGVADYA 86
+C N C+ + C C + C + +PC S PC+ + TC V+ G +
Sbjct: 38 SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATC--VNTPGERSFL 95
Query: 87 CSCALGFSG---------------------------PLCLTPLDNA----------CLTN 109
C C G+SG P+C+ P A C ++
Sbjct: 96 CKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASS 155
Query: 110 PCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPP 168
PC+NG C + Y C C PG+ G+ C + D CAS+PC N CL Y C CP
Sbjct: 156 PCQNGAVCQD-GIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPH 214
Query: 169 SFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQ 228
++ G C +++EC +P C +G TC + +G+Y C C G +CE C+ PC
Sbjct: 215 NYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCL 272
Query: 229 NGGTCRPTGDVTHECACL-PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEW 287
+GG C G+ + C C GFTG +CE + C C N C D V+ Y C C P +
Sbjct: 273 HGGLC-VDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGY 331
Query: 288 TGQYCTEDVDECQLMPNACQNGGTC--------------------HNTHGGYNCVCVNGW 327
TG C D++EC N CQ+ G C ++ GY C+C G+
Sbjct: 332 TGAQCEIDLNECN--SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF 389
Query: 328 TGEDCSENIDDCASAACFHGATCHDRVASFYCECPH---GRT---GLLC-HLNDACISNP 380
TG C E++++C+S C +G TC + ++ C CP RT G C + C
Sbjct: 390 TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQ 449
Query: 381 CNEGSNCDTNPVNGK--AICTCPSGYTGPAC 409
C C + +G+ C CPSGYTG C
Sbjct: 450 CLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 186 bits (473), Expect = 2e-46
Identities = 75/197 (38%), Positives = 112/197 (56%), Gaps = 8/197 (4%)
Query: 868 VDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGIN 927
+ +N C +PC HG +C++ + Y C C G+SG++CE +ID+C NPC +G +C+D +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
Query: 928 TAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNT--- 984
C C PG+ G CE DI+ C S C NGA C + Y+C C F+G C +
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 985 ----PDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGC 1040
+ T +C+NGG C + C+C PGFTG +C+ D++EC S PC++GG CQD
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 1041 GSYRCTCPQGYTGPNCQ 1057
++C C + G C+
Sbjct: 1317 NKFQCLCDVAFAGERCE 1333
Score = 181 bits (458), Expect = 1e-44
Identities = 77/197 (39%), Positives = 113/197 (57%), Gaps = 8/197 (4%)
Query: 604 INECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYE 663
+N C+S PC HGG C+D ++Y C C G +G +CE+N+D+C S+PC G C D++ Y
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYH 1199
Query: 664 CACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSE------- 716
C CEPGYTG C ++ID C + C NG TC NG++C C + C
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
Query: 717 VNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGY 775
NE + C +G C + KC C PG++G C+ + +EC S+PCVNGG C+D+ + +
Sbjct: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
Query: 776 VCTCREGFSGPNCQTNI 792
C C F+G C+ ++
Sbjct: 1320 QCLCDVAFAGERCEVDL 1336
Score = 180 bits (457), Expect = 1e-44
Identities = 81/202 (40%), Positives = 112/202 (55%), Gaps = 9/202 (4%)
Query: 451 IDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
+ +N C SNPC + C D + C C G+ G HCE+N DEC S+PC+H G C D++
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVA 1196
Query: 511 EFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE------ 564
+ C C G+TG C+ D+D C S C NGA C+ N Y+C+C +TG C
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 565 -VDIDECDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRD 622
V +E C+ G +C + C+CRPG+TG CE +I+EC+S PC +GG CQD
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 623 NAYLCFCLKGTTGPNCEINLDD 644
N + C C G CE++L D
Sbjct: 1317 NKFQCLCDVAFAGERCEVDLAD 1338
Score = 178 bits (451), Expect = 7e-44
Identities = 79/197 (40%), Positives = 105/197 (53%), Gaps = 10/197 (5%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
C +PC +GG C + Y S+ C CP GW G+ CE++I+EC +PC HG +C + Y
Sbjct: 1143 CNSNPCLHGGNCE--DIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYH 1199
Query: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDI------ 946
C C+ GY+G NCE DID+C+ + C NG +C N C C F G FC +
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
Query: 947 -NECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSF 1005
NE + C NG NCT+ C C GF+G CE + +C C NGG C D +N F
Sbjct: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
Query: 1006 TCLCPPGFTGSYCQHDV 1022
CLC F G C+ D+
Sbjct: 1320 QCLCDVAFAGERCEVDL 1336
Score = 176 bits (446), Expect = 3e-43
Identities = 77/207 (37%), Positives = 114/207 (55%), Gaps = 9/207 (4%)
Query: 677 INIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNG 736
+ ++ C NPC +GG CED + + C CP G+ C ++EC SNPC+HG C D +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
Query: 737 YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI---- 792
Y C C+PG++G NC+++ + C+S+ C NG TC T+GY C C F+G C+ +
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 793 ---NECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSED 849
NE + C N G C + KC C +TG CE + CA PC NGG C+ +
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQ--DL 1315
Query: 850 YESFSCVCPTGWQGQTCEVDINECVLS 876
F C+C + G+ CEVD+ + ++S
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 172 bits (437), Expect = 3e-42
Identities = 76/190 (40%), Positives = 104/190 (54%), Gaps = 8/190 (4%)
Query: 532 CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLC 591
C S PC +G C D ++Y C C G++G HCE++IDEC +PC +G+C D VA + C C
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTC 1202
Query: 592 RPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCE-------INLDD 644
PGYTG +CE +I+ C S C +G TC N Y C C TG C + ++
Sbjct: 1203 EPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNE 1262
Query: 645 CASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR 703
+ C + G C + +C C PG+TG C +IDECA +PC NGG C+D +N F C
Sbjct: 1263 KTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCL 1322
Query: 704 CPEGYHDPTC 713
C + C
Sbjct: 1323 CDVAFAGERC 1332
Score = 171 bits (433), Expect = 8e-42
Identities = 77/205 (37%), Positives = 109/205 (53%), Gaps = 12/205 (5%)
Query: 370 CHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC 429
C + C SNPC G NC+ + C+CP G++G C ++DEC +NPC H G C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCED--IYSSYHCSCPLGWSGKHCELNIDECF--SNPCIH-GNC 1191
Query: 430 INTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCE- 488
+ + ++ C C GYTG CE+D++ C S+ C N ATC+ + C+C + G C
Sbjct: 1192 SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
Query: 489 ------VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAK 542
V +E + C + G C + E +C C GFTG C+ D+DECAS PC NG
Sbjct: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
Query: 543 CLDGPNTYTCVCTEGYTGTHCEVDI 567
C D N + C+C + G CEVD+
Sbjct: 1312 CQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 166 bits (421), Expect = 2e-40
Identities = 81/209 (38%), Positives = 115/209 (55%), Gaps = 10/209 (4%)
Query: 792 INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYE 851
+N C SNPCL+ G C D + Y C+C L ++G CE+ + C +PC +G C S+
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-C--SDRVA 1196
Query: 852 SFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCE------ 905
++ C C G+ G CEVDI+ C C +GA+C + GY C C ++G+ C
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 906 TDIDDCRPN-PCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCV 964
T + + N C+NGG+CT+ C C PGF G +CE+DI+ECASDPC NG C D +
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 965 DSYTCTCPAGFSGIHCENNTPDCTESSCF 993
+ + C C F+G CE + D S F
Sbjct: 1317 NKFQCLCDVAFAGERCEVDLADDLISDIF 1345
Score = 163 bits (413), Expect = 2e-39
Identities = 75/206 (36%), Positives = 106/206 (51%), Gaps = 12/206 (5%)
Query: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCT 1046
C + C +GG C D +S+ C CP G++G +C+ +++EC S PC+HG C D +Y CT
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
Query: 1047 CPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD---VPSVSCEV 1103
C GYTG NC+ + C S C NG C Y C C +TG +C +PS C
Sbjct: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC-- 1259
Query: 1104 AAQRQGVDVARL-CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTD 1162
G + L C +GG C + C C+ G+TG +CE +DEC+ PC NG C D
Sbjct: 1260 -----GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
Query: 1163 YLGGYSCKCVAGYHGVNCSEEIDECL 1188
L + C C + G C ++ + L
Sbjct: 1315 LLNKFQCLCDVAFAGERCEVDLADDL 1340
Score = 162 bits (409), Expect = 5e-39
Identities = 94/296 (31%), Positives = 129/296 (43%), Gaps = 40/296 (13%)
Query: 29 ETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYAC 87
+ C N C G C+C + G C+ + + C S PC N TC + + Y C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC----QDALGAYFC 248
Query: 88 SCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCP-PGWSGKSCQQADP-CA 145
CA GF G C D C + PC +GG C + Y C C G++G C+ P C
Sbjct: 249 DCAPGFLGDHCELNTDE-CASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPLCW 306
Query: 146 SNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC---------- 195
S PC N C +Y CHC P + G C D+NEC P C+ G C
Sbjct: 307 SKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNP--CQSNGECVELSSEKQYG 364
Query: 196 ----------HNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRP-TGDVTHEC- 243
++E Y C+C+ TG +CE CS +PCQNGGTC G+ T C
Sbjct: 365 RITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424
Query: 244 ---ACLPGFTGQNCEENIDDCPGNNCKNGGACV----DGVNTYNCRCPPEWTGQYC 292
+ G++C + + C C N G C+ DG + ++C CP +TG C
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 160 bits (406), Expect = 1e-38
Identities = 74/210 (35%), Positives = 108/210 (51%), Gaps = 18/210 (8%)
Query: 1022 VNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQY 1081
+N C+S PCLHGG C+D SY C+CP G++G +C+ + C S+PC +G C Y
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
Query: 1082 RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSY 1141
C C G+TG+ C+V +C+ + C +G C+ N + C C +TG +
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQ----------SHQCANGATCISHTNGYSCLCFGNFTGKF 1248
Query: 1142 CED-------LVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQN 1194
C +E + C NG CT++ C C G+ G C ++IDEC S PC N
Sbjct: 1249 CRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
Query: 1195 GGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1224
GG C DL N ++C C G CE+++ D
Sbjct: 1309 GGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 160 bits (405), Expect = 1e-38
Identities = 97/263 (36%), Positives = 127/263 (48%), Gaps = 43/263 (16%)
Query: 25 SQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVA 83
SQP CLNG C+ A G C C F+G C+ + + C S PC + G C VD G
Sbjct: 230 SQP---CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLC--VD--GEN 282
Query: 84 DYACSC-ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QA 141
Y+C+C GF+G C T L C + PC N TC+ ++ Y C C PG++G C+
Sbjct: 283 RYSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATCE-DSVDNYTCHCWPGYTGAQCEIDL 340
Query: 142 DPCASNPCANGGQCLPF-------------------EAS-YICHCPPSFHGPTCRQDVNE 181
+ C SNPC + G+C+ EAS Y+C C P F G C +DVNE
Sbjct: 341 NECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNE 400
Query: 182 CGQKPGLCRHGGTCHNEVGSYRCVC------RATHTGPNCERPYVPCSPSPCQNGGTCRP 235
C P C++GGTC N G+Y C C R + G +C + C+ C N GTC P
Sbjct: 401 CSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP 458
Query: 236 ---TGDVTHECACLPGFTGQNCE 255
G C C G+TG CE
Sbjct: 459 HFQDGQHGFSCLCPSGYTGSLCE 481
Score = 158 bits (399), Expect = 7e-38
Identities = 76/199 (38%), Positives = 100/199 (50%), Gaps = 13/199 (6%)
Query: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKAI 397
C S C HG C D +S++C CP G +G C LN D C SNPC G NC
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYH-- 1199
Query: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE------- 450
CTC GYTG C D+D C ++ C + CI+ + C C +TG C
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQ--SHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 451 IDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
+ NE + C N C + E +C+C PG+ G CE + DECAS PC++ G C D +N
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
Query: 511 EFQCECPTGFTGHLCQYDV 529
+FQC C F G C+ D+
Sbjct: 1318 KFQCLCDVAFAGERCEVDL 1336
Score = 157 bits (396), Expect = 2e-37
Identities = 76/217 (35%), Positives = 102/217 (47%), Gaps = 26/217 (11%)
Query: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
C+S+PC +GG C ++ Y C CP GW+G +C++ C + C HG C
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC----------FSNPCIHGN-C 1191
Query: 1123 VDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSE 1182
D +HC C+ GYTG CE +D C C NGATC + GYSC C + G C +
Sbjct: 1192 SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
Query: 1183 EI-------DECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRS 1235
+E + C NGG C + KC C G G CE ++D+C S
Sbjct: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------AS 1303
Query: 1236 PKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECL 1272
C N G C D + + C C F GERCE D+ + L
Sbjct: 1304 DPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
Score = 155 bits (393), Expect = 4e-37
Identities = 75/201 (37%), Positives = 103/201 (51%), Gaps = 13/201 (6%)
Query: 104 NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASY 162
N C +NPC +GG C+ + + Y C CP GWSGK C+ D C SNPC +G C A+Y
Sbjct: 1141 NVCNSNPCLHGGNCEDI-YSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
Query: 163 ICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC 222
C C P + G C D++ C C +G TC + Y C+C TG C + +P
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 223 SPS-------PCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDG 275
+ C NGG C +C C PGFTG+ CE++ID+C + C NGG C D
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
Query: 276 VNTYNCRCPPEWTGQYCTEDV 296
+N + C C + G+ C D+
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDL 1336
Score = 147 bits (372), Expect = 1e-34
Identities = 77/211 (36%), Positives = 103/211 (48%), Gaps = 25/211 (11%)
Query: 1183 EIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDC--NPPVDPVSRSPKCFN 1240
+++ C S+PC +GG C D+ ++Y CSCP G G HCE+N+D+C NP +
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI----------- 1187
Query: 1241 NGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT 1300
+G C D+V Y CTC PG+ G CE D++ C S+ C A G C+ N + C C T
Sbjct: 1188 HGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC-ANGA-TCISHTNGYSCLCFGNFT 1245
Query: 1301 GRRCE-----SVINGCK--GKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCG 1353
G+ C S + G + C NGG C + C C GF G CE D C
Sbjct: 1246 GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELK---CMCRPGFTGEWCEKDIDECA 1302
Query: 1354 SLRCLNGGTCISGPRSPTCLCLGPFTGPECQ 1384
S C+NGG C CLC F G C+
Sbjct: 1303 SDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
Score = 147 bits (372), Expect = 1e-34
Identities = 76/207 (36%), Positives = 97/207 (46%), Gaps = 21/207 (10%)
Query: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS 1208
C+ +PC +G C D Y C C G+ G +C IDEC S+PC +G C D Y C+
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
Query: 1209 CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDV 1268
C G GV+CE+++D+C +S +C N TC+ GYSC C F G+ C
Sbjct: 1202 CEPGYTGVNCEVDIDNC--------QSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSR 1253
Query: 1269 -------NECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGT 1321
NE + C G NC + + C CR G TG CE I+ C PC NGG
Sbjct: 1254 LPSTVCGNEKTNLTCYNGG--NCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
Query: 1322 CAVASNTARGFICKCPAGFEGATCEND 1348
C N F C C F G CE D
Sbjct: 1312 CQDLLNK---FQCLCDVAFAGERCEVD 1335
Score = 146 bits (368), Expect = 3e-34
Identities = 72/208 (34%), Positives = 101/208 (48%), Gaps = 13/208 (6%)
Query: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHN 197
C Q + C SNPC +GG C +SY C CP + G C +++EC P C H G C +
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP--CIH-GNCSD 1193
Query: 198 EVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEEN 257
V +Y C C +TG NCE C C NG TC + + C C FTG+ C ++
Sbjct: 1194 RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN-GYSCLCFGNFTGKFCRQS 1252
Query: 258 I-------DDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGG 310
++ C NGG C + C C P +TG++C +D+DEC P C NGG
Sbjct: 1253 RLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGG 1310
Query: 311 TCHNTHGGYNCVCVNGWTGEDCSENIDD 338
C + + C+C + GE C ++ D
Sbjct: 1311 LCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 145 bits (365), Expect = 7e-34
Identities = 69/200 (34%), Positives = 96/200 (48%), Gaps = 9/200 (4%)
Query: 179 VNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGD 238
+N C P C HGG C + SY C C +G +CE C +PC +G
Sbjct: 1140 LNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVA- 1196
Query: 239 VTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDE 298
+ C C PG+TG NCE +ID+C + C NG C+ N Y+C C +TG++C +
Sbjct: 1197 -AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 299 CQLMPN-----ACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDR 353
+ N C NGG C C+C G+TGE C ++ID+CAS C +G C D
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
Query: 354 VASFYCECPHGRTGLLCHLN 373
+ F C C G C ++
Sbjct: 1316 LNKFQCLCDVAFAGERCEVD 1335
Score = 137 bits (346), Expect = 1e-31
Identities = 76/210 (36%), Positives = 103/210 (49%), Gaps = 14/210 (6%)
Query: 57 CQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGT 116
C N C S PC + G C + + Y CSC LG+SG C +D C +NPC +G
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDI----YSSYHCSCPLGWSGKHCELNIDE-CFSNPCIHGNC 1191
Query: 117 CDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTC 175
D + Y C C PG++G +C+ D C S+ CANG C+ Y C C +F G C
Sbjct: 1192 SD--RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFC 1249
Query: 176 RQD---VNECG-QKPGL-CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNG 230
RQ CG +K L C +GG C +C+CR TG CE+ C+ PC NG
Sbjct: 1250 RQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNG 1309
Query: 231 GTCRPTGDVTHECACLPGFTGQNCEENIDD 260
G C+ + +C C F G+ CE ++ D
Sbjct: 1310 GLCQDLLN-KFQCLCDVAFAGERCEVDLAD 1338
Score = 135 bits (340), Expect = 5e-31
Identities = 72/203 (35%), Positives = 94/203 (46%), Gaps = 17/203 (8%)
Query: 1232 VSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDF 1291
V S C + G C D Y C+CP G+ G+ CE +++EC SNPC G NC RV +
Sbjct: 1142 VCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHG--NCSDRVAAY 1198
Query: 1292 HCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEND--- 1348
HC C G+TG CE I+ C+ C NG TC +N G+ C C F G C
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN---GYSCLCFGNFTGKFCRQSRLP 1255
Query: 1349 ARTCGS----LRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCE 1404
+ CG+ L C NGG C C+C FTG C+ +PC N G C+
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE--CASDPCVNGGLCQ 1313
Query: 1405 PTSESPFYRCLCPAKFNGLLCHI 1427
++CLC F G C +
Sbjct: 1314 DLLNK--FQCLCDVAFAGERCEV 1334
Score = 133 bits (335), Expect = 2e-30
Identities = 96/337 (28%), Positives = 137/337 (40%), Gaps = 39/337 (11%)
Query: 1235 SPKCFNNGTCVDQVGGYSCTCPP--GFVGERCEGDVNECLSNPCDARGTQNCVQRVND-- 1290
S C NN TC D C+C + + C+ + C SNPC +G+ CV +
Sbjct: 36 SNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPC--QGSATCVNTPGERS 93
Query: 1291 FHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDAR 1350
F C+C G++G CE+ I C C++GG C +C CPAG+ G CE D
Sbjct: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP---VCICPAGYAGRFCEIDHD 150
Query: 1351 TCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESP 1410
C S C NG C G +C C+ + G C +PC N+ TC +E
Sbjct: 151 ECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE--CASDPCKNEATC--LNEIG 206
Query: 1411 FYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNH 1470
Y C+CP ++G+ C + +I + CQ+ G C
Sbjct: 207 RYTCICPHNYSGVNCEL-----------EIDECWSQPCLNGATCQDALGAYFCDC----- 250
Query: 1471 ACGWDGGDCSLNFND-PWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQC- 1528
A G+ G C LN ++ + C C DG CN G F G C+ C
Sbjct: 251 APGFLGDHCELNTDECASQPCLHGGLC----VDGENRYSCNCTGSGFTGTHCETLMPLCW 306
Query: 1529 -NPLYDQY-CKDHFSDG--HCDQGCNSAECEWDGLDC 1561
P ++ C+D + HC G A+CE D +C
Sbjct: 307 SKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNEC 343
Score = 120 bits (302), Expect = 1e-26
Identities = 67/195 (34%), Positives = 96/195 (49%), Gaps = 18/195 (9%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
CL+GG CE + C C + G C+ + + C S PC + G C DR VA Y C+C
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCS--DR--VAAYHCTC 1202
Query: 90 ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ----ADPCA 145
G++G C +DN C ++ C NG TC + Y C C ++GK C+Q + C
Sbjct: 1203 EPGYTGVNCEVDIDN-CQSHQCANGATC-ISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG 1260
Query: 146 SN----PCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGS 201
+ C NGG C F+ C C P F G C +D++EC P C +GG C + +
Sbjct: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNK 1318
Query: 202 YRCVCRATHTGPNCE 216
++C+C G CE
Sbjct: 1319 FQCLCDVAFAGERCE 1333
Score = 64.7 bits (156), Expect = 1e-09
Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 103 DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASY 162
DN+C +NPC NGG C ++ C CP SGK+C++ C +PC +G QC P +
Sbjct: 888 DNSCKSNPCHNGGVCHS-RWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGF 946
Query: 163 ICHCPPSFHG 172
C F+G
Sbjct: 947 ECIANAVFNG 956
Score = 63.9 bits (154), Expect = 2e-09
Identities = 28/71 (39%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
C +PC NGG C ++ FSC CP G+ CE ++ C SPC HGA CQ G+
Sbjct: 891 CKSNPCHNGGVCHSR--WDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 893 CHCQAGYSGRN 903
C A ++G++
Sbjct: 948 CIANAVFNGQS 958
Score = 63.5 bits (153), Expect = 2e-09
Identities = 36/118 (30%), Positives = 50/118 (42%), Gaps = 8/118 (6%)
Query: 1308 INGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGP 1367
+N C PC +GG C + + C CP G+ G CE + C S C++G C
Sbjct: 1140 LNVCNSNPCLHGGNC---EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRV 1195
Query: 1368 RSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
+ C C +TG C+ + + C N TC S + Y CLC F G C
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDN--CQSHQCANGATC--ISHTNGYSCLCFGNFTGKFC 1249
Score = 60.8 bits (146), Expect = 2e-08
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 680 DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYK 738
+ C NPCHNGG C + F+C CP C EV C +PC HGA C+ L G++
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 739 CDCDPGWSGTNCDI 752
C + ++G + I
Sbjct: 948 CIANAVFNGQSGQI 961
Score = 56.2 bits (134), Expect = 4e-07
Identities = 27/76 (35%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 902 RNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCT 961
+ C D + C+ NPCHNGG C + C C G CEE + C PC +GA C
Sbjct: 883 QGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQ 940
Query: 962 DCVDSYTCTCPAGFSG 977
+ + C A F+G
Sbjct: 941 PVLQGFECIANAVFNG 956
Score = 55.8 bits (133), Expect = 5e-07
Identities = 68/260 (26%), Positives = 87/260 (33%), Gaps = 55/260 (21%)
Query: 1345 CENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTG--PECQFPASSPCLGGNPCYNQGT 1402
C + C S C N TC + C C +C PC NPC T
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCD-NMKDPCFS-NPCQGSAT 84
Query: 1403 CEPTSESPFYRCLCPAKFNGLLCHILDYSFG------GGAGRDIP--PPLI--------- 1445
C T + C CP ++G +C S G GG P P I
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 1446 ----EEACELPECQEDAGNKVCSLQCNNHAC----GWDGGDCSLNF----NDPWKNCTQS 1493
+ C CQ A VC + ++C G+ G C L +DP KN
Sbjct: 145 CEIDHDECASSPCQNGA---VCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
Query: 1494 LQ--------CWKYFSDGHCD---SQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSD 1542
L C +S +C+ +C S CL +G CQ A G Y C F
Sbjct: 202 LNEIGRYTCICPHNYSGVNCELEIDECWSQPCL-NGATCQDALG----AYFCDCAPGFLG 256
Query: 1543 GHCD---QGCNSAECEWDGL 1559
HC+ C S C GL
Sbjct: 257 DHCELNTDECASQPCLHGGL 276
Score = 55.5 bits (132), Expect = 7e-07
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 1023 NECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1082
N C S PC +GG C + C+CP +G C+ V WC SPC +G +C +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1083 C 1083
C
Sbjct: 948 C 948
Score = 55.1 bits (131), Expect = 9e-07
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 12/103 (11%)
Query: 913 PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 972
PNP +N +N + G G N C S+PC NG C D ++C+CP
Sbjct: 866 PNPTNNAS-----LNPVLVNVTQGCAGD------NSCKSNPCHNGGVCHSRWDDFSCSCP 914
Query: 973 AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTG 1015
A SG CE C S C +G C + F C+ F G
Sbjct: 915 ALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVFNG 956
Score = 54.7 bits (130), Expect = 1e-06
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 136 KSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC 195
+ C + C SNPC NGG C + C CP G C ++V CG P C HG C
Sbjct: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSP--CPHGAQC 939
Query: 196 HNEVGSYRCVCRATHTG 212
+ + C+ A G
Sbjct: 940 QPVLQGFECIANAVFNG 956
Score = 53.1 bits (126), Expect = 3e-06
Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 605 NECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT-CLDKIDGYE 663
N C S PC +GG C R + + C C T+G CE + C SPC G C + G+E
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 664 CACEPGYTG 672
C + G
Sbjct: 948 CIANAVFNG 956
Score = 52.0 bits (123), Expect = 7e-06
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 492 DECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYT 551
+ C S+PC + G C + ++F C CP +G C+ +V C +PC +GA+C +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 552 CVCTEGYTG 560
C+ + G
Sbjct: 948 CIANAVFNG 956
Score = 51.6 bits (122), Expect = 1e-05
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Query: 754 NNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGY 813
+N C+SNPC NGG C + C+C SG C+ + C +PC + C + G+
Sbjct: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGF 946
Query: 814 KCNCLLPYTGATCEVV 829
+C + G + +++
Sbjct: 947 ECIANAVFNGQSGQIL 962
Score = 51.6 bits (122), Expect = 1e-05
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCT 1046
C + C NGG C + F+C CP +G C+ +V C PC HG CQ + C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
Query: 1047 CPQGYTGPNCQNL 1059
+ G + Q L
Sbjct: 950 ANAVFNGQSGQIL 962
Score = 51.2 bits (121), Expect = 1e-05
Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 1/69 (1%)
Query: 454 NECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513
N C SNPC N C + +F C C G CE C SPC H +C + F+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 514 CECPTGFTG 522
C F G
Sbjct: 948 CIANAVFNG 956
Score = 50.8 bits (120), Expect = 2e-05
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 18/110 (16%)
Query: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRC 283
P+P N +VT CA G N C N C NGG C + ++C C
Sbjct: 866 PNPTNNASLNPVLVNVTQGCA------GDN------SCKSNPCHNGGVCHSRWDDFSCSC 913
Query: 284 PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC---VNGWTGE 330
P +G+ C E+V C P C +G C G+ C+ NG +G+
Sbjct: 914 PALTSGKAC-EEVQWCGFSP--CPHGAQCQPVLQGFECIANAVFNGQSGQ 960
Score = 49.3 bits (116), Expect = 5e-05
Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Query: 30 TCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACS 88
TC NGG C C+C F G C+ D + C S PC N G C + + + C
Sbjct: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL----LNKFQCL 1322
Query: 89 CALGFSGPLC 98
C + F+G C
Sbjct: 1323 CDVAFAGERC 1332
Score = 48.1 bits (113), Expect = 1e-04
Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 5/69 (7%)
Query: 370 CHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC 429
C +++C SNPC+ G C + + C+CP+ +G AC ++V C G +PC H +C
Sbjct: 885 CAGDNSCKSNPCHNGGVCHSRWDDFS--CSCPALTSGKAC-EEVQWC--GFSPCPHGAQC 939
Query: 430 INTLGSFEC 438
L FEC
Sbjct: 940 QPVLQGFEC 948
Score = 48.1 bits (113), Expect = 1e-04
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
C +GG+C + C C A +G CE+ V C SPC +GA C L G+ C A +
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 1176 HG 1177
+G
Sbjct: 955 NG 956
Score = 47.8 bits (112), Expect = 1e-04
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV 239
N C P C +GG CH+ + C C A +G CE C SPC +G C+P
Sbjct: 889 NSCKSNP--CHNGGVCHSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQ- 944
Query: 240 THECACLPGFTGQN 253
EC F GQ+
Sbjct: 945 GFECIANAVFNGQS 958
Score = 47.4 bits (111), Expect = 2e-04
Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Query: 1309 NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPR 1368
N CK PC NGG C + F C CPA G CE + + CG C +G C +
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQ 944
Query: 1369 SPTCLCLGPFTGPECQ 1384
C+ F G Q
Sbjct: 945 GFECIANAVFNGQSGQ 960
Score = 46.6 bits (109), Expect = 3e-04
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 623 NAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDE 681
N L +G G N C S+PC + G C + D + C+C +G C +
Sbjct: 875 NPVLVNVTQGCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQW 927
Query: 682 CAGNPCHNGGTCEDGINGFTC 702
C +PC +G C+ + GF C
Sbjct: 928 CGFSPCPHGAQCQPVLQGFEC 948
Score = 46.6 bits (109), Expect = 3e-04
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 304 NACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC 359
N C NGG CH+ ++C C +G+ C E + C + C HGA C + F C
Sbjct: 894 NPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFEC 948
Score = 45.4 bits (106), Expect = 7e-04
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206
+ C +PC NG C +SC C A G C EE+ C PC +G C + ++
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1207 C 1207
C
Sbjct: 948 C 948
Score = 45.1 bits (105), Expect = 0.001
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 15/100 (15%)
Query: 292 CTEDV----DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHG 347
C +DV + PN N N V VN G C+ + + C S C +G
Sbjct: 851 CIQDVRLNNQNLEFFPNPTNNASL--------NPVLVNVTQG--CAGD-NSCKSNPCHNG 899
Query: 348 ATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNC 387
CH R F C CP +G C C +PC G+ C
Sbjct: 900 GVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
Score = 45.1 bits (105), Expect = 0.001
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 417 SLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQC 476
S +NPC + G C + F C C +G CE +V C +PC + A C + F+C
Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFEC 948
Query: 477 ICMPGYEG 484
I + G
Sbjct: 949 IANAVFNG 956
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 864 QTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCT 923
Q C D N C +PC +G C + + C C A SG+ CE ++ C +PC +G C
Sbjct: 883 QGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQ 940
Query: 924 DGINTAFCDCLPGFRG 939
+ C F G
Sbjct: 941 PVLQGFECIANAVFNG 956
Score = 44.7 bits (104), Expect = 0.001
Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 15/96 (15%)
Query: 1185 DECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC 1244
+ C S+PC NGG C + + CSCP T G CE V SP C + C
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE--------EVQWCGFSP-CPHGAQC 939
Query: 1245 VDQVGGYSCTCPPGFVGE------RCEGDVNECLSN 1274
+ G+ C F G+ R G++ L+N
Sbjct: 940 QPVLQGFECIANAVFNGQSGQILFRSNGNITRELTN 975
Score = 43.5 bits (101), Expect = 0.003
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 7/83 (8%)
Query: 57 CQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGT 116
C N C S PC N G CH D++CSC SG C C +PC +G
Sbjct: 885 CAGDNSCKSNPCHNGGVCH----SRWDDFSCSCPALTSGKACEEV--QWCGFSPCPHGAQ 938
Query: 117 CDLLTLTEYKCRCPPGWSGKSCQ 139
C + L ++C ++G+S Q
Sbjct: 939 CQPV-LQGFECIANAVFNGQSGQ 960
Score = 42.4 bits (98), Expect = 0.006
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 530 DECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGS-CKDGVATFT 588
+ C S PC NG C + ++C C +G CE ++ C PC +G+ C+ + F
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 589 CLCRPGYTG 597
C+ + G
Sbjct: 948 CIANAVFNG 956
Score = 40.8 bits (94), Expect = 0.017
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 568 DECDPDPCHYGS-CKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYL 626
+ C +PCH G C F+C C +G CE + C PC HG CQ +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 627 C 627
C
Sbjct: 948 C 948
Score = 40.4 bits (93), Expect = 0.023
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD 178
C + D C S PC + G+C+ SY C C + GP C ++
Sbjct: 670 CVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
Score = 40.4 bits (93), Expect = 0.023
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNC 788
+ + CES PC + G C ++ Y C C + GPNC
Sbjct: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 40.4 bits (93), Expect = 0.023
Identities = 16/32 (50%), Positives = 20/32 (62%)
Query: 1025 CDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 1056
C+SQPC G C + SY+C C + Y GPNC
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 39.7 bits (91), Expect = 0.038
Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 1345 CENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCE 1404
C D +C S C NGG C S +C C +G C+ G +PC + C+
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE---EVQWCGFSPCPHGAQCQ 940
Query: 1405 PTSESPFYRCLCPAKFNGLLCHILDYSFG 1433
P + + C+ A FNG IL S G
Sbjct: 941 PVLQG--FECIANAVFNGQSGQILFRSNG 967
Score = 39.3 bits (90), Expect = 0.050
Identities = 32/105 (30%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 1230 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVN 1289
D +S C N G C + +SC+CP G+ CE +V C +PC G Q C +
Sbjct: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPC-PHGAQ-CQPVLQ 944
Query: 1290 DFHCECRAGHTGRRCESVINGCKGKPC--KNGGTCAVASNTARGF 1332
F C A V NG G+ NG +N GF
Sbjct: 945 GFECIANA---------VFNGQSGQILFRSNGNITRELTNITFGF 980
Score = 38.9 bits (89), Expect = 0.066
Identities = 15/34 (44%), Positives = 22/34 (64%)
Query: 1185 DECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHC 1218
D C S PCQ+ G C++L +Y+C C R +G +C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 38.9 bits (89), Expect = 0.066
Identities = 41/163 (25%), Positives = 62/163 (38%), Gaps = 36/163 (22%)
Query: 1395 NPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPEC 1454
NPC + G CE S Y C CP ++G C + I+E P
Sbjct: 1146 NPCLHGGNCEDIYSS--YHCSCPLGWSGKHCEL----------------NIDECFSNPCI 1187
Query: 1455 QEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGC 1514
+ ++V + C G+ G +C ++ + NC QS QC + C S N C
Sbjct: 1188 HGNCSDRVAAYHCTCEP-GYTGVNCEVDID----NC-QSHQC---ANGATCISHTNGYSC 1238
Query: 1515 L----FDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAE 1553
L F G C+++ L C + ++ C G N E
Sbjct: 1239 LCFGNFTGKFCRQSR-----LPSTVCGNEKTNLTCYNGGNCTE 1276
Score = 38.5 bits (88), Expect = 0.086
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATC 826
C S PC ++G CI+ Y+C+C PY G C
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 38.5 bits (88), Expect = 0.086
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 420 ANPCEHAGKCINTLGSFECQCLQGYTGPRC 449
+ PC+ G+CIN S++C C + Y GP C
Sbjct: 678 SQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 38.5 bits (88), Expect = 0.086
Identities = 26/91 (28%), Positives = 32/91 (35%), Gaps = 17/91 (18%)
Query: 1049 QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQ 1108
QG G N C S+PC NGG C + C CP+ +G C+ Q
Sbjct: 883 QGCAGDNS------CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE--------EVQWC 928
Query: 1109 GVDVARLCQHGGLCVDAGNTHHCRCQAGYTG 1139
G C HG C C A + G
Sbjct: 929 GFSP---CPHGAQCQPVLQGFECIANAVFNG 956
Score = 37.7 bits (86), Expect = 0.15
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 1062 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 1094
WC+S PC++ G+C Y+C+C + G C
Sbjct: 675 WCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 37.4 bits (85), Expect = 0.19
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 6/83 (7%)
Query: 640 INLDDCASSPCDSGTCLD-KIDGYECACEPGYTGSMCNINI-----DECAGNPCHNGGTC 693
+N + S+P G D KID E +GS N+ D C PC + G C
Sbjct: 628 LNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGCVRKDWCESQPCQSRGRC 687
Query: 694 EDGINGFTCRCPEGYHDPTCLSE 716
+ + C C Y P CL E
Sbjct: 688 INLWLSYQCDCHRPYEGPNCLRE 710
Score = 36.2 bits (82), Expect = 0.43
Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 182 CGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYV 220
C +P C+ G C N SY+C C + GPNC R YV
Sbjct: 676 CESQP--CQSRGRCINLWLSYQCDCHRPYEGPNCLREYV 712
Score = 35.8 bits (81), Expect = 0.56
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 489 VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLC 525
V D C S PC GRC++ +QC+C + G C
Sbjct: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 35.0 bits (79), Expect = 0.95
Identities = 14/37 (37%), Positives = 16/37 (43%)
Query: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE 1183
D C PCQ+ C + Y C C Y G NC E
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
Score = 34.7 bits (78), Expect = 1.2
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
C SQPC+ G C + +Y C C + GPNC
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 33.9 bits (76), Expect = 2.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHC 487
C S PCQ+ C++ +QC C YEG +C
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.7 bits (73), Expect = 4.7
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 14/90 (15%)
Query: 662 YECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN 721
Y P + G + +I ID N T E+ +G + G C+ + + C
Sbjct: 631 YNMPSTPSFVGCLQDIKID-------WNHITLENISSGSSLNVKAG-----CVRK-DWCE 677
Query: 722 SNPCV-HGACRDSLNGYKCDCDPGWSGTNC 750
S PC G C + Y+CDC + G NC
Sbjct: 678 SQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.7 bits (73), Expect = 4.7
Identities = 14/47 (29%), Positives = 20/47 (42%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVV 77
C NGG C + +C C G C++ C +PC + C V
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPV 942
Score = 32.7 bits (73), Expect = 4.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 ETCLNGGKCEAANGTEACVCGGAFVGPRCQ 58
+ C+NGG C+ C+C AF G RC+
Sbjct: 1304 DPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
Score = 32.3 bits (72), Expect = 6.1
Identities = 12/34 (35%), Positives = 19/34 (55%)
Query: 530 DECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHC 563
D C S PC++ +C++ +Y C C Y G +C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.0 bits (71), Expect = 8.0
Identities = 12/32 (37%), Positives = 14/32 (43%)
Query: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNC 904
C PC+ C N Y+C C Y G NC
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 348 bits (894), Expect = 3e-95
Identities = 161/390 (41%), Positives = 217/390 (55%), Gaps = 38/390 (9%)
Query: 437 ECQCLQ--GYT-GPRCEIDVNECVSNPCQNDATCLDQIGE---FQCICMPGYEGVHCEVN 490
ECQ + GYT GP ++ C + PC + A C+ Q + F+C C+PG++G CE++
Sbjct: 52 ECQATESGGYTCGP---MEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELD 108
Query: 491 TDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTY 550
DECAS PC H C + + ++C CP G+ G C+ +VDECAS PC +G CLDG ++
Sbjct: 109 IDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSF 168
Query: 551 TCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCR-PGYTGHHCETNINECS 608
CVC GY GT C++D+DEC PC H G+C D V F C C GY G HCE + EC+
Sbjct: 169 RCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECA 228
Query: 609 SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD-SGTCLDKID------- 660
S PC H +C + ++ C C G +G CE++ D+CASSPC G CL + D
Sbjct: 229 SAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGV 288
Query: 661 --------------GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPE 706
G+ C C PG+ G+ C + +DECA PC NGG C+D NGF C CP+
Sbjct: 289 QAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPD 348
Query: 707 GYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNG 765
GY PTC +V+EC S+PC+HG C D++ GY C C W G +C + C+ + C
Sbjct: 349 GYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLA 408
Query: 766 GTC----KDMTSGYVCTCREGFSGPNCQTN 791
TC + YVC C G GP C N
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
Score = 338 bits (868), Expect = 3e-92
Identities = 161/412 (39%), Positives = 215/412 (52%), Gaps = 47/412 (11%)
Query: 375 ACISNPCNEGSNCDTNPVNGKAICTCPSGYT-GPACSQDVDECSLGANPCEHAGKCINT- 432
AC S+PC G+ C T GYT GP ++ PC H C+
Sbjct: 41 ACASDPCAPGTECQA---------TESGGYTCGP-----MEPRGCATQPCHHGALCVPQG 86
Query: 433 --LGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN 490
F C C+ G+ GPRCE+D++EC S PC + ATC + ++C C GY GV CE+
Sbjct: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Query: 491 TDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTY 550
DECAS+PCLH G CLD + F+C C G+ G CQ D+DEC S PC +G C D N +
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 551 TCVCT-EGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECS 608
C C GY GTHCE ++ EC PC H SC +G+ +F CLC PGY+G CE + +EC+
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 609 SQPCRHGGTCQDRDN---------------------AYLCFCLKGTTGPNCEINLDDCAS 647
S PC+HGG C R + +LC C G G +C + +D+CAS
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 648 SPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPE 706
PC + G C D +G++C C GY G C ++DEC +PC +GGTC D + G+ CRCPE
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPE 386
Query: 707 GYHDPTCLSEVNECNSNPCVHGAC-----RDSLNGYKCDCDPGWSGTNCDIN 753
+ C ++ C + C A ++ Y C C PG G C N
Sbjct: 387 TWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
Score = 336 bits (862), Expect = 2e-91
Identities = 197/634 (31%), Positives = 281/634 (44%), Gaps = 87/634 (13%)
Query: 607 CSSQPCRHGGTCQDRDNA-YLCFCLKGTTGPNCEINLDDCASSPCDSGT-CLDK---IDG 661
C+S PC G CQ ++ Y C GP + CA+ PC G C+ + G
Sbjct: 42 CASDPCAPGTECQATESGGYTC-------GP---MEPRGCATQPCHHGALCVPQGPDPTG 91
Query: 662 YECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN 721
+ C C PG+ G C ++IDECA PCH+G TC + + + C CP GY TC EV+EC
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 722 SNPCVHG-ACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR 780
S PC+HG +C D + ++C C PG+ GT C ++ +EC+S PC +GGTC D+ +G+ C C
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 781 -EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
G+ G +C+ + ECAS PC + +C++ + ++C C Y+G CEV CA SPC+
Sbjct: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
Query: 840 NGGECRQSED-------------------YESFSCVCPTGWQGQTCEVDINECVLSPCRH 880
+GG C Q D F C CP G++G C V+++EC PC +
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLN 331
Query: 881 GASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGT 940
G CQ+ G++CHC GY+G CE D+D+C +PC +GG+C+D + C C + G
Sbjct: 332 GGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGR 391
Query: 941 FCEEDINECASDPCRNGANCTDC----VDSYTCTCPAGFSGIHCENNTPDCT------ES 990
C + C C A C V SY C CP G G C NT ++
Sbjct: 392 DCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQA 451
Query: 991 SCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQG 1050
S GG + T L P G + ++D E + L T Q SY T
Sbjct: 452 SVPAGGPLGLALRFRTTL-PAGTLAT--RNDTKE-SLELALVAATLQATLWSYSTTVLVL 507
Query: 1051 YTGPNCQNLVHW--------------------CDSSPCKNGGKCWQTHTQYRCECPSGWT 1090
N HW C + C G T P+G
Sbjct: 508 RLPDLALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATPLPAG-- 565
Query: 1091 GLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS 1150
+ S A + R+ H L D G C+ ++C
Sbjct: 566 -----ISSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVLLGCERR----------EQCR 610
Query: 1151 PSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
P PC +G +C D + C C + G C++EI
Sbjct: 611 PLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 317 bits (811), Expect = 1e-85
Identities = 162/422 (38%), Positives = 209/422 (49%), Gaps = 58/422 (13%)
Query: 873 CVLSPCRHGASCQNTH-GGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCT-DGIN-TA 929
C PC G CQ T GGY C R C T PCH+G C G + T
Sbjct: 42 CASDPCAPGTECQATESGGYTC---GPMEPRGCATQ-------PCHHGALCVPQGPDPTG 91
Query: 930 F-CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCT 988
F C C+PGF+G CE DI+ECAS PC +GA C + D Y C CP G++G+ CE +C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 989 ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCP 1048
+ C +GG+C+DG+ SF C+C PG+ G+ CQ D++EC SQPC HGGTC D +RC C
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 1049 -QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQR 1107
GY G +C+ V C S+PC++ C + +RC C G++G C+V C
Sbjct: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDEC------ 265
Query: 1108 QGVDVARLCQHGGLCVD----------------AGNTHH-----CRCQAGYTGSYCEDLV 1146
+ CQHGG C+ A + H C C G+ G+ C V
Sbjct: 266 ----ASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEV 321
Query: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206
DEC+ PC NG C D G+ C C GY G C E++DECLS PC +GGTC D Y
Sbjct: 322 DECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381
Query: 1207 CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV----DQVGGYSCTCPPGFVGE 1262
C CP G C + + C P++ TC+ V Y C CPPG G
Sbjct: 382 CRCPETWGGRDCSVQLTGCQGHTCPLA--------ATCIPIFESGVHSYVCHCPPGTHGP 433
Query: 1263 RC 1264
C
Sbjct: 434 FC 435
Score = 308 bits (789), Expect = 4e-83
Identities = 159/452 (35%), Positives = 211/452 (46%), Gaps = 53/452 (11%)
Query: 795 CASNPCLNQGTC-IDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGEC-RQSEDYES 852
CAS+PC C + GY C + P CA PC +G C Q D
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP----------RGCATQPCHHGALCVPQGPDPTG 91
Query: 853 FSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCR 912
F C C G+QG CE+DI+EC PC HGA+C+N Y CHC GY+G CE ++D+C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 913 PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 972
PC +GGSC DG+ + C C PG+ GT C+ D++EC S PC +G C D V+ + C C
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 973 -AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL 1031
G+ G HCE +C + C + +C++G+ SF CLC PG++G C+ D +EC S PC
Sbjct: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
Query: 1032 HGGTCQD---------------GCGSYR------CTCPQGYTGPNCQNLVHWCDSSPCKN 1070
HGG C G S+R C CP G+ G +C V C S PC N
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLN 331
Query: 1071 GGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1130
GG C ++C CP G+ G C+ C ++ C HGG C D +
Sbjct: 332 GGHCQDLPNGFQCHCPDGYAGPTCEEDVDEC----------LSDPCLHGGTCSDTVAGYI 381
Query: 1131 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDY----LGGYSCKCVAGYHGVNCSEE--I 1184
CRC + G C + C C ATC + Y C C G HG C +
Sbjct: 382 CRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTF 441
Query: 1185 DECLSHPCQ---NGGTCLDLPNTYKCSCPRGT 1213
P Q G L L ++ + P GT
Sbjct: 442 SVMAGSPIQASVPAGGPLGLALRFRTTLPAGT 473
Score = 306 bits (783), Expect = 2e-82
Identities = 147/404 (36%), Positives = 204/404 (50%), Gaps = 41/404 (10%)
Query: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLC-QYDVDECASTPCKNGAKCLD---GPNT 549
CAS PC C T G+ C + CA+ PC +GA C+ P
Sbjct: 42 CASDPCAPGTECQ----------ATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTG 91
Query: 550 YTCVCTEGYTGTHCEVDIDECDPDPCHYGS-CKDGVATFTCLCRPGYTGHHCETNINECS 608
+ C C G+ G CE+DIDEC PCH+G+ C++ + C C GY G CE ++EC+
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 609 SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACE 667
S PC HGG+C D ++ C C G G C+++LD+C S PC GTC D ++G+ C C
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 668 -PGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV 726
GY G+ C + ECA PC + +C +G+ F C C GY C + +EC S+PC
Sbjct: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
Query: 727 HGA-CRDSLN---------------------GYKCDCDPGWSGTNCDINNNECESNPCVN 764
HG C + G+ C C PG+ G +C + +EC S PC+N
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLN 331
Query: 765 GGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGA 824
GG C+D+ +G+ C C +G++GP C+ +++EC S+PCL+ GTC D VAGY C C + G
Sbjct: 332 GGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGR 391
Query: 825 TCEVVLAPCAPSPCRNGGECRQ--SEDYESFSCVCPTGWQGQTC 866
C V L C C C S+ C CP G G C
Sbjct: 392 DCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 283 bits (723), Expect = 2e-75
Identities = 155/451 (34%), Positives = 220/451 (48%), Gaps = 39/451 (8%)
Query: 2 PPLLAPLLCLAL-LPALAA-RGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQD 59
P LA +L L L PAL+ G S+P C + C +A GG GP +
Sbjct: 11 PQALASVLLLLLWAPALSLLAGTVPSEPPSACASD-PCAPGTECQATESGGYTCGP--ME 67
Query: 60 PNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDL 119
P C + PC + C V + C C GF GP C +D C + PC +G TC
Sbjct: 68 PRGCATQPCHHGALC-VPQGPDPTGFRCYCVPGFQGPRCELDIDE-CASRPCHHGATCRN 125
Query: 120 LTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD 178
L Y+C CP G++G +C+ + D CAS PC +GG CL S+ C C P + G C+ D
Sbjct: 126 LA-DRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLD 184
Query: 179 VNECGQKPGLCRHGGTCHNEVGSYRCVCRAT-HTGPNCERPYVPCSPSPCQNGGTCRPTG 237
++EC +P C HGGTCH+ V +RC C T + G +CER + C+ +PC++ +C G
Sbjct: 185 LDECQSQP--CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLE-G 241
Query: 238 DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVD--------GVNT----------- 278
+ C C PG++G+ CE + D+C + C++GG C+ GV
Sbjct: 242 LGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHA 301
Query: 279 --YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI 336
+ C CPP + G C +VDEC P C NGG C + G+ C C +G+ G C E++
Sbjct: 302 AGFLCHCPPGFEGADCGVEVDECASRP--CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDV 359
Query: 337 DDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNG- 394
D+C S C HG TC D VA + C CP G C + C + C + C +G
Sbjct: 360 DECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419
Query: 395 -KAICTCPSGYTGPACSQDVDECSLGANPCE 424
+C CP G GP C Q+ + +P +
Sbjct: 420 HSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQ 450
Score = 281 bits (718), Expect = 8e-75
Identities = 151/460 (32%), Positives = 204/460 (44%), Gaps = 60/460 (13%)
Query: 911 CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDC---VDSY 967
C +PC G C + C P + CA+ PC +GA C +
Sbjct: 42 CASDPCAPGTEC-QATESGGYTCGP--------MEPRGCATQPCHHGALCVPQGPDPTGF 92
Query: 968 TCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDS 1027
C C GF G CE + +C C +G TC + + + C CP G+ G C+ +V+EC S
Sbjct: 93 RCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS 152
Query: 1028 QPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP- 1086
PCLHGG+C DG GS+RC C GY G CQ + C S PC +GG C +RC+C
Sbjct: 153 APCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAG 212
Query: 1087 SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLV 1146
+G+ G +C+ + C A C+H C++ + C C GY+G CE
Sbjct: 213 TGYEGTHCEREVLECASAP----------CEHNASCLEGLGSFRCLCWPGYSGELCEVDE 262
Query: 1147 DECSPSPCQNGATCTD---------------------YLGGYSCKCVAGYHGVNCSEEID 1185
DEC+ SPCQ+G C + G+ C C G+ G +C E+D
Sbjct: 263 DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD 322
Query: 1186 ECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV 1245
EC S PC NGG C DLPN ++C CP G G CE +VD+C S C + GTC
Sbjct: 323 ECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDEC--------LSDPCLHGGTCS 374
Query: 1246 DQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCV----QRVNDFHCECRAGHTG 1301
D V GY C CP + G C + C + C T C+ V+ + C C G G
Sbjct: 375 DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAAT--CIPIFESGVHSYVCHCPPGTHG 432
Query: 1302 RRC--ESVINGCKGKPCKNGGTCAVASNTARGFICKCPAG 1339
C + + G P + A F PAG
Sbjct: 433 PFCGQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAG 472
Score = 271 bits (694), Expect = 5e-72
Identities = 140/418 (33%), Positives = 195/418 (46%), Gaps = 48/418 (11%)
Query: 104 NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPF---EA 160
+AC ++PC G C Y C + CA+ PC +G C+P
Sbjct: 40 SACASDPCAPGTECQATESGGYTC---------GPMEPRGCATQPCHHGALCVPQGPDPT 90
Query: 161 SYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYV 220
+ C+C P F GP C D++EC +P C HG TC N Y C C + G CE
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCEMEVD 148
Query: 221 PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280
C+ +PC +GG+C G + C C PG+ G C+ ++D+C C +GG C D VN +
Sbjct: 149 ECASAPCLHGGSCLD-GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207
Query: 281 CRCPPE-WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC 339
C C + G +C +V EC P C++ +C G + C+C G++GE C + D+C
Sbjct: 208 CDCAGTGYEGTHCEREVLECASAP--CEHNASCLEGLGSFRCLCWPGYSGELCEVDEDEC 265
Query: 340 ASAACFHGATCHDR---------------------VASFYCECPHGRTGLLCHLN-DACI 377
AS+ C HG C R A F C CP G G C + D C
Sbjct: 266 ASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECA 325
Query: 378 SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFE 437
S PC G +C P NG C CP GY GP C +DVDEC ++PC H G C +T+ +
Sbjct: 326 SRPCLNGGHCQDLP-NGFQ-CHCPDGYAGPTCEEDVDECL--SDPCLHGGTCSDTVAGYI 381
Query: 438 CQCLQGYTGPRCEIDVNECVSNPCQNDATCL----DQIGEFQCICMPGYEGVHCEVNT 491
C+C + + G C + + C + C ATC+ + + C C PG G C NT
Sbjct: 382 CRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNT 439
Score = 258 bits (659), Expect = 5e-68
Identities = 155/490 (31%), Positives = 207/490 (42%), Gaps = 105/490 (21%)
Query: 939 GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC 998
GT E + CASDPC G C TES GG
Sbjct: 32 GTVPSEPPSACASDPCAPGTEC-------------------------QATES----GG-- 60
Query: 999 VDGINSFTC--LCPPGFTGSYCQHDVNECDSQPCLHGGTC----QDGCGSYRCTCPQGYT 1052
+TC + P G C +QPC HG C D G +RC C G+
Sbjct: 61 ------YTCGPMEPRG------------CATQPCHHGALCVPQGPDPTG-FRCYCVPGFQ 101
Query: 1053 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112
GP C+ + C S PC +G C +Y C CP G+ G+ C++ C A
Sbjct: 102 GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAP------- 154
Query: 1113 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV 1172
C HGG C+D + C C GY G+ C+ +DEC PC +G TC D + G+ C C
Sbjct: 155 ---CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 1173 A-GYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDP 1231
GY G +C E+ EC S PC++ +CL+ +++C C G G CE++ D+C
Sbjct: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDEC------ 265
Query: 1232 VSRSPKCFNNGTCVDQ---------------------VGGYSCTCPPGFVGERCEGDVNE 1270
S C + G C+ + G+ C CPPGF G C +V+E
Sbjct: 266 --ASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
Query: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1330
C S PC G +C N F C C G+ G CE ++ C PC +GGTC S+T
Sbjct: 324 CASRPCLNGG--HCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC---SDTVA 378
Query: 1331 GFICKCPAGFEGATCENDARTCGSLRCLNGGTCI----SGPRSPTCLCLGPFTGPECQFP 1386
G+IC+CP + G C C C TCI SG S C C GP C
Sbjct: 379 GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
Query: 1387 ASSPCLGGNP 1396
+ + G+P
Sbjct: 439 TTFSVMAGSP 448
Score = 246 bits (627), Expect = 3e-64
Identities = 136/387 (35%), Positives = 178/387 (45%), Gaps = 55/387 (14%)
Query: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
C S PC G +C T + G Y P A Q C HG LC
Sbjct: 42 CASDPCAPGTECQATES-----------GGYTCGPMEPRGCATQP--------CHHGALC 82
Query: 1123 VDAG---NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVN 1179
V G C C G+ G CE +DEC+ PC +GATC + Y C C GY GV
Sbjct: 83 VPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVT 142
Query: 1180 CSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF 1239
C E+DEC S PC +GG+CLD +++C C G G C++++D+C +S C
Sbjct: 143 CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDEC--------QSQPCA 194
Query: 1240 NNGTCVDQVGGYSCTCP-PGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
+ GTC D V G+ C C G+ G CE +V EC S PC+ + C++ + F C C G
Sbjct: 195 HGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNAS--CLEGLGSFRCLCWPG 252
Query: 1299 HTGRRCESVINGCKGKPCKNGGTCAVASNTA------------------RGFICKCPAGF 1340
++G CE + C PC++GG C S+ A GF+C CP GF
Sbjct: 253 YSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF 312
Query: 1341 EGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQ 1400
EGA C + C S CLNGG C P C C + GP C+ CL +PC +
Sbjct: 313 EGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDE-CL-SDPCLHG 370
Query: 1401 GTCEPTSESPFYRCLCPAKFNGLLCHI 1427
GTC T Y C CP + G C +
Sbjct: 371 GTCSDTVAG--YICRCPETWGGRDCSV 395
Score = 168 bits (425), Expect = 7e-41
Identities = 116/422 (27%), Positives = 162/422 (38%), Gaps = 84/422 (19%)
Query: 1149 CSPSPCQNGATC-TDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDL---PNT 1204
C+ PC G C GGY+C + E C + PC +G C+ P
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPM----------EPRGCATQPCHHGALCVPQGPDPTG 91
Query: 1205 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERC 1264
++C C G QG CE+++D+C S C + TC + Y C CP G+ G C
Sbjct: 92 FRCYCVPGFQGPRCELDIDEC--------ASRPCHHGATCRNLADRYECHCPLGYAGVTC 143
Query: 1265 EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAV 1324
E +V+EC S PC G+ C+ V F C C G+ G RC+ ++ C+ +PC +GGTC
Sbjct: 144 EMEVDECASAPCLHGGS--CLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC-- 199
Query: 1325 ASNTARGFICKCPA-GFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC 1383
+ GF C C G+EG CE + C S C + +C+ G S CLC ++G C
Sbjct: 200 -HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELC 258
Query: 1384 QFP----ASSPCLGGNPCYNQ------GTCEPTSESPF-------YRCLCPAKF------ 1420
+ ASSPC G C + G + F + C CP F
Sbjct: 259 EVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCG 318
Query: 1421 ---------------------NGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAG 1459
NG CH D G D+ L + C +
Sbjct: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVA 378
Query: 1460 NKVCSLQCNNHACGWDGGDCSLNFND-PWKNCTQSLQCWKYFSDG------HCDSQCNSA 1512
+C +C W G DCS+ C + C F G HC +
Sbjct: 379 GYIC--RCPE---TWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGP 433
Query: 1513 GC 1514
C
Sbjct: 434 FC 435
Score = 119 bits (299), Expect = 3e-26
Identities = 57/160 (35%), Positives = 80/160 (50%), Gaps = 4/160 (2%)
Query: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNG-YKCD 740
CA +PC + G C D + F C C G+ P C + V+ C+S PC G C +G ++C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 741 CDPGWSGTNC--DINNNECESN-PCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECAS 797
C PG+ G C + + EC N C++G C+ + C+C EG +G CQ C +
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 798 NPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSP 837
NPCLN GTC +C C ++G CEV P P
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLP 1219
Score = 118 bits (296), Expect = 7e-26
Identities = 56/153 (36%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Query: 720 CNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCT 778
C +PC+H GACRD + + C C PGW G C+ + + C S PC G + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 779 CREGFSGPNCQTNI--NECASN-PCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP 835
C GF GP C+ + EC+ N CL+ C C+CL G C+V PC
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 836 SPCRNGGECRQSEDYESFSCVCPTGWQGQTCEV 868
+PC NGG CR + C+C + GQ CEV
Sbjct: 1180 NPCLNGGTCRAAGGVS--ECICNARFSGQFCEV 1210
Score = 118 bits (295), Expect = 9e-26
Identities = 61/153 (39%), Positives = 73/153 (47%), Gaps = 6/153 (3%)
Query: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYIC 164
C +PC + G C L + C C PGW G C+ DPC S PCA G + + C
Sbjct: 1060 CAPSPCLHDGACRDL-FDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
Query: 165 HCPPSFHGPTCRQDV--NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC 222
CPP F GP CR V EC C G C + C C G C+ P +PC
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNV-TCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 223 SPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
+PC NGGTCR G V+ EC C F+GQ CE
Sbjct: 1178 EANPCLNGGTCRAAGGVS-ECICNARFSGQFCE 1209
Score = 115 bits (289), Expect = 4e-25
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 5/152 (3%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
CAPSPC + G CR +++F+C C GW+G CE ++ C +PC G + G +
Sbjct: 1060 CAPSPCLHDGACRDL--FDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117
Query: 893 CHCQAGYSGRNCETDI--DDCRPN-PCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINEC 949
C C G+ G C + +C N C +G C G A C CL G G C+ C
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 950 ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCE 981
++PC NG C C C A FSG CE
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 115 bits (288), Expect = 6e-25
Identities = 57/150 (38%), Positives = 71/150 (47%), Gaps = 5/150 (3%)
Query: 645 CASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR 703
CA SPC G C D D + CAC PG+ G C ++D C PC G F CR
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 704 CPEGYHDPTCLSEV--NECNSN-PCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECES 759
CP G+ P C V EC+ N C+ G+ C C C G +G C + CE+
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 760 NPCVNGGTCKDMTSGYVCTCREGFSGPNCQ 789
NPC+NGGTC+ C C FSG C+
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 115 bits (287), Expect = 7e-25
Identities = 56/151 (37%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
Query: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDG-YECA 665
C+ PC H G C+D +A+ C C G GP CE ++D C S+PC G C DG +EC
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 666 CEPGYTGSMCNINI--DECAGN-PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNS 722
C PG+ G C + + EC+ N C +G CE G C C EG C C +
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 723 NPCVH-GACRDSLNGYKCDCDPGWSGTNCDI 752
NPC++ G CR + +C C+ +SG C++
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 114 bits (285), Expect = 1e-24
Identities = 55/151 (36%), Positives = 75/151 (49%), Gaps = 6/151 (3%)
Query: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC-LDKINEFQC 514
C +PC +D C D F C C PG+EG CE + D C S+PC GRC F+C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
Query: 515 ECPTGFTGHLCQYDV--DECA-STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECD 571
CP GF G C+ V EC+ + C +G+ C G C C EG G C+V C+
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 572 PDPC-HYGSCKDGVATFTCLCRPGYTGHHCE 601
+PC + G+C+ C+C ++G CE
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 111 bits (278), Expect = 8e-24
Identities = 52/150 (34%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
Query: 911 CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCT 970
C P+PC + G+C D + C C PG+ G CE ++ C S PC G T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 971 CPAGFSGIHCENNTP--DCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDS 1027
CP GF G C P +C+ +C +G C G + C C G G CQ C++
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 1028 QPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
PCL+GGTC+ G C C ++G C+
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 108 bits (271), Expect = 5e-23
Identities = 55/162 (33%), Positives = 72/162 (44%), Gaps = 13/162 (8%)
Query: 985 PDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYR 1044
P C S C + G C D ++F C C PG+ G C+ V+ C S PC G G +
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117
Query: 1045 CTCPQGYTGPNCQNLVHWCDSS---PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC 1101
C CP G+ GP C+ V + S C +G C C C G G C VP++ C
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 1102 EVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143
E A C +GG C AG C C A ++G +CE
Sbjct: 1178 E----------ANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 108 bits (269), Expect = 9e-23
Identities = 51/151 (33%), Positives = 71/151 (47%), Gaps = 3/151 (1%)
Query: 949 CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCL 1008
CA PC + C D D++ C C G+ G CE + C + C G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 1009 CPPGFTGSYCQHDV--NECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDS 1065
CPPGF G C+ V EC + CL G C+ G + C+C +G G CQ C++
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 1066 SPCKNGGKCWQTHTQYRCECPSGWTGLYCDV 1096
+PC NGG C C C + ++G +C+V
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 105 bits (261), Expect = 7e-22
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 6/152 (3%)
Query: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN-TYTC 552
CA SPCLH+G C D + F C C G+ G C+ VD C S PC G +C P+ + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 553 VCTEGYTGTHCEVDID--ECDPD-PCHYGS-CKDGVATFTCLCRPGYTGHHCETNINECS 608
C G+ G C + + EC + C GS C+ G C C G G C+ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 609 SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI 640
+ PC +GGTC+ C C +G CE+
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 104 bits (259), Expect = 1e-21
Identities = 51/148 (34%), Positives = 65/148 (43%), Gaps = 3/148 (2%)
Query: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP 480
+PC H G C + +F C C G+ GPRCE V+ C S PC G F+C C P
Sbjct: 1063 SPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPP 1122
Query: 481 GYEGVHCE--VNTDECA-SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPC 537
G+ G C V + EC+ + CL C C C G G CQ C + PC
Sbjct: 1123 GFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPC 1182
Query: 538 KNGAKCLDGPNTYTCVCTEGYTGTHCEV 565
NG C C+C ++G CEV
Sbjct: 1183 LNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 100 bits (250), Expect = 1e-20
Identities = 48/150 (32%), Positives = 68/150 (45%), Gaps = 3/150 (2%)
Query: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCD 932
C SPC H +C++ + C C G+ G CE +D C PC G T C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 933 CLPGFRGTFCEEDI--NECASD-PCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTE 989
C PGF G C + EC+ + C +G+ C + C+C G +G C+ T C
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 990 SSCFNGGTCVDGINSFTCLCPPGFTGSYCQ 1019
+ C NGGTC C+C F+G +C+
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 98.6 bits (244), Expect = 7e-20
Identities = 50/154 (32%), Positives = 64/154 (41%), Gaps = 15/154 (9%)
Query: 570 CDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCF 628
C P PC H G+C+D F C C PG+ G CE +++ C S PC G D + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 629 CLKGTTGP---------NCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINI 679
C G GP C +N+ SPC+ G+ C+C G G C +
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGS-----PAANCSCLEGLAGQRCQVPT 1174
Query: 680 DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC 713
C NPC NGGTC C C + C
Sbjct: 1175 LPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 98.2 bits (243), Expect = 9e-20
Identities = 55/160 (34%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHN 197
C+ A CA +PC + G C ++ C C P + GP C V+ C P C G CH
Sbjct: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP--CARG-RCHT 1110
Query: 198 EV-GSYRCVCRATHTGPNCERPYVP---CSPS-PCQNGGTCRPTGDVTHECACLPGFTGQ 252
G + C C GP C P VP CS + C +G C G C+CL G GQ
Sbjct: 1111 HPDGRFECRCPPGFGGPRCRLP-VPSKECSLNVTCLDGSPCEG-GSPAANCSCLEGLAGQ 1168
Query: 253 NCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC 292
C+ C N C NGG C C C ++GQ+C
Sbjct: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 96.3 bits (238), Expect = 3e-19
Identities = 48/157 (30%), Positives = 68/157 (43%), Gaps = 7/157 (4%)
Query: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS 1208
C+PSPC + C D ++C C G+ G C +D C S PC G ++C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 1209 CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDV 1268
CP G G C + V P S + C + C +C+C G G+RC+
Sbjct: 1120 CPPGFGGPRCRLPV-----PSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPT 1174
Query: 1269 NECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE 1305
C +NPC GT V++ C C A +G+ CE
Sbjct: 1175 LPCEANPCLNGGTCRAAGGVSE--CICNARFSGQFCE 1209
Score = 94.7 bits (234), Expect = 1e-18
Identities = 59/181 (32%), Positives = 81/181 (44%), Gaps = 17/181 (9%)
Query: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1330
C +PC G C + F C C G G RCE+ ++ C PC G ++
Sbjct: 1060 CAPSPCLHDGA--CRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG---RCHTHPDG 1114
Query: 1331 GFICKCPAGFEGATCEND--ARTCG-SLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPA 1387
F C+CP GF G C ++ C ++ CL+G C G + C CL G CQ P
Sbjct: 1115 RFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP- 1173
Query: 1388 SSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEE 1447
+ PC NPC N GTC + C+C A+F+G C + G +P PL+E
Sbjct: 1174 TLPC-EANPCLNGGTCR--AAGGVSECICNARFSGQFCEV-----AKGLPLPLPFPLLEV 1225
Query: 1448 A 1448
A
Sbjct: 1226 A 1226
Score = 92.0 bits (227), Expect = 7e-18
Identities = 53/163 (32%), Positives = 69/163 (42%), Gaps = 8/163 (4%)
Query: 1231 PVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVND 1290
PV C ++G C D ++C C PG+ G RCE V+ C S PC ARG +
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARGRCH-THPDGR 1115
Query: 1291 FHCECRAGHTGRRCESVINGCK---GKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN 1347
F C C G G RC + + C +G C S A C C G G C+
Sbjct: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN---CSCLEGLAGQRCQV 1172
Query: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSP 1390
C + CLNGGTC + C+C F+G C+ P
Sbjct: 1173 PTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLP 1215
Score = 91.7 bits (226), Expect = 9e-18
Identities = 59/166 (35%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 15 PALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGT 73
P L RG P CL+ G C AC CG + GPRC+ +PC S PC G
Sbjct: 1050 PILGCRGAPVCAPSP-CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GR 1107
Query: 74 CHV-VDRRGVADYACSCALGFSGPLCLTPLDN--ACLTNPCRNGGTCDLLTLTEYKCRCP 130
CH D R + C C GF GP C P+ + L C +G C+ + C C
Sbjct: 1108 CHTHPDGR----FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGS-PAANCSCL 1162
Query: 131 PGWSGKSCQQAD-PCASNPCANGGQCLPFEASYICHCPPSFHGPTC 175
G +G+ CQ PC +NPC NGG C C C F G C
Sbjct: 1163 EGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 89.4 bits (220), Expect = 4e-17
Identities = 50/154 (32%), Positives = 67/154 (43%), Gaps = 10/154 (6%)
Query: 303 PNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRV-ASFYCEC 361
P+ C + G C + + C C GW G C ++D C SA C G CH F C C
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFECRC 1120
Query: 362 PHGRTGLLCHL----NDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS 417
P G G C L + ++ C +GS C+ + A C+C G G C C
Sbjct: 1121 PPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGG--SPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 418 LGANPCEHAGKCINTLGSFECQCLQGYTGPRCEI 451
ANPC + G C G EC C ++G CE+
Sbjct: 1179 --ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 89.0 bits (219), Expect = 6e-17
Identities = 57/180 (31%), Positives = 78/180 (43%), Gaps = 21/180 (11%)
Query: 42 GTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVAD-YACSCALGFSGPLCLT 100
GT A + G C+ C +PC + G C R + D +AC+C G+ GP C
Sbjct: 1046 GTPAPILG-------CRGAPVCAPSPCLHDGAC-----RDLFDAFACACGPGWEGPRCEA 1093
Query: 101 PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP---CASN-PCANGGQCL 156
+D C + PC G C ++CRCPPG+ G C+ P C+ N C +G C
Sbjct: 1094 HVD-PCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCE 1151
Query: 157 PFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCE 216
+ C C G C+ C P C +GGTC G C+C A +G CE
Sbjct: 1152 GGSPAANCSCLEGLAGQRCQVPTLPCEANP--CLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 88.2 bits (217), Expect = 9e-17
Identities = 51/153 (33%), Positives = 64/153 (41%), Gaps = 11/153 (7%)
Query: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
C H G C D + C C G+ G CE VD C +PC G T G + C+C G+
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 1176 HGVNCSEEI--DEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPV 1232
G C + EC L+ C +G C CSC G G C++ P P
Sbjct: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV-------PTLPC 1177
Query: 1233 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
+P C N GTC G C C F G+ CE
Sbjct: 1178 EANP-CLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 80.9 bits (198), Expect = 2e-14
Identities = 47/161 (29%), Positives = 60/161 (37%), Gaps = 13/161 (8%)
Query: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
C SPC + G C + C C GW G C+ C A C G
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP----------CARGRCH 1109
Query: 1123 VDAGNTHHCRCQAGYTGSYCEDLVD--ECSPS-PCQNGATCTDYLGGYSCKCVAGYHGVN 1179
CRC G+ G C V ECS + C +G+ C +C C+ G G
Sbjct: 1110 THPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQR 1169
Query: 1180 CSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEI 1220
C C ++PC NGGTC +C C G CE+
Sbjct: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 79.3 bits (194), Expect = 4e-14
Identities = 48/155 (30%), Positives = 66/155 (42%), Gaps = 12/155 (7%)
Query: 261 CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTH--GG 318
C + C + GAC D + + C C P W G C VD C P A G CH TH G
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA---RGRCH-THPDGR 1115
Query: 319 YNCVCVNGWTGEDCSENI--DDCA-SAACFHGATCHDRVASFYCECPHGRTGLLCHLND- 374
+ C C G+ G C + +C+ + C G+ C + C C G G C +
Sbjct: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL 1175
Query: 375 ACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
C +NPC G C G + C C + ++G C
Sbjct: 1176 PCEANPCLNGGTC--RAAGGVSECICNARFSGQFC 1208
Score = 59.3 bits (142), Expect = 5e-08
Identities = 59/269 (21%), Positives = 92/269 (34%), Gaps = 57/269 (21%)
Query: 1309 NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATC-ENDARTCGSLRCLNGGTCISGP 1367
+ C PC G C + G TC + R C + C +G C+
Sbjct: 40 SACASDPCAPGTECQATESG-------------GYTCGPMEPRGCATQPCHHGALCVPQG 86
Query: 1368 RSPT---CLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLL 1424
PT C C+ F GP C+ PC++ TC ++ Y C CP + G+
Sbjct: 87 PDPTGFRCYCVPGFQGPRCELDIDE--CASRPCHHGATCRNLADR--YECHCPLGYAGVT 142
Query: 1425 CHILDYSFGGGAGRDIPPPLIEEACELP-----ECQEDAGNKVCSLQCNNHACGWDGGDC 1479
C + ++E P C + G+ C A G+ G C
Sbjct: 143 CEME----------------VDECASAPCLHGGSCLDGVGSFRCVC-----APGYGGTRC 181
Query: 1480 SLNFNDPWKN-CTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPL---YDQY 1535
L+ ++ C C + CD AG ++G C+R +C ++
Sbjct: 182 QLDLDECQSQPCAHGGTCHDLVNGFRCDC----AGTGYEGTHCEREVLECASAPCEHNAS 237
Query: 1536 CKDHFSDGH--CDQGCNSAECEWDGLDCA 1562
C + C G + CE D +CA
Sbjct: 238 CLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Score = 58.5 bits (140), Expect = 8e-08
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCT 1046
C+ CFNGGTC+ N F C CP FTG C + C QPCL TC++ + C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 1047 C--------PQGYTGPNCQN 1058
P ++G N +
Sbjct: 870 AEATFREGPPAAFSGHNASS 889
Score = 57.4 bits (137), Expect = 2e-07
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 745 WSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQG 804
W+ T ++ + C +PC NGGTC + + CTC F+GP C + C PCL
Sbjct: 799 WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPA 857
Query: 805 TCIDDVAGYKC 815
TC + G+ C
Sbjct: 858 TCEEVPDGFVC 868
Score = 57.4 bits (137), Expect = 2e-07
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 489 VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN 548
V+ D C+ PC + G CL N+F C CP FTG C + C PC A C + P+
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 549 TYTCV 553
+ CV
Sbjct: 865 GFVCV 869
Score = 55.8 bits (133), Expect = 5e-07
Identities = 28/72 (38%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHN 197
C D C+ +PC NGG CL + C CP +F GPTC Q + GQ C TC
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQP---CLPPATCEE 861
Query: 198 EVGSYRCVCRAT 209
+ CV AT
Sbjct: 862 VPDGFVCVAEAT 873
Score = 55.5 bits (132), Expect = 7e-07
Identities = 44/144 (30%), Positives = 59/144 (40%), Gaps = 19/144 (13%)
Query: 1219 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGG-YSCTCPPGFVGERCEGDVNECLSNPCD 1277
++ +D C+ P P+ +N + ++GG S G V E + C +PC
Sbjct: 769 DLRLDGCHLPFFPLP-----LDNSSQPSELGGRQSWNLTAGCVSE------DMCSPDPCF 817
Query: 1278 ARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCP 1337
GT C+ NDFHC C A TG C + C G+PC TC GF+C
Sbjct: 818 NGGT--CLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATC---EEVPDGFVCVAE 871
Query: 1338 AGF-EGATCENDARTCGSLRCLNG 1360
A F EG S R L G
Sbjct: 872 ATFREGPPAAFSGHNASSGRLLGG 895
Score = 53.9 bits (128), Expect = 2e-06
Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 9/77 (11%)
Query: 909 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYT 968
D C P+PC NGG+C N C C F G C + + C PC A C + D +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 969 CTC--------PAGFSG 977
C PA FSG
Sbjct: 868 CVAEATFREGPPAAFSG 884
Score = 53.5 bits (127), Expect = 3e-06
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206
D CSP PC NG TC + C C A + G C++++ C PC TC ++P+ +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 1207 C 1207
C
Sbjct: 868 C 868
Score = 53.1 bits (126), Expect = 3e-06
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 103 DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASY 162
++ C +PC NGGTC L+T ++ C CP ++G +C Q C PC C +
Sbjct: 808 EDMCSPDPCFNGGTC-LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGF 866
Query: 163 ICHCPPSF-HGP 173
+C +F GP
Sbjct: 867 VCVAEATFREGP 878
Score = 52.8 bits (125), Expect = 4e-06
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 677 INIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLN 735
++ D C+ +PC NGGTC N F C CP + PTC ++ C PC+ A C + +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 736 GYKC 739
G+ C
Sbjct: 865 GFVC 868
Score = 50.8 bits (120), Expect = 2e-05
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
C+P PC NGG C + + F C CP + G TC + C PC A+C+ G+
Sbjct: 811 CSPDPCFNGGTCLVT--WNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 893 CHCQAGY 899
C +A +
Sbjct: 868 CVAEATF 874
Score = 50.1 bits (118), Expect = 3e-05
Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 11/87 (12%)
Query: 713 CLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDM 771
C+SE + C+ +PC +G C + N + C C ++G C C PC+ TC+++
Sbjct: 805 CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEV 862
Query: 772 TSGYVC----TCREG----FSGPNCQT 790
G+VC T REG FSG N +
Sbjct: 863 PDGFVCVAEATFREGPPAAFSGHNASS 889
Score = 49.7 bits (117), Expect = 4e-05
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 640 INLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGIN 698
++ D C+ PC + GTCL + + C C +TG C + C G PC TCE+ +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 699 GFTC 702
GF C
Sbjct: 865 GFVC 868
Score = 48.1 bits (113), Expect = 1e-04
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 949 CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCL 1008
C+ DPC NG C + + CTCPA F+G C C C TC + + F C+
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 1009 CPPGF 1013
F
Sbjct: 870 AEATF 874
Score = 47.8 bits (112), Expect = 1e-04
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECA 665
CS PC +GGTC N + C C TGP C L C PC TC + DG+ C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 666 CE 667
E
Sbjct: 870 AE 871
Score = 45.8 bits (107), Expect = 5e-04
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 21/112 (18%)
Query: 215 CERPYVPC----SPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGG 270
C P+ P S P + GG R + ++T C + D C + C NGG
Sbjct: 775 CHLPFFPLPLDNSSQPSELGG--RQSWNLTAGCV------------SEDMCSPDPCFNGG 820
Query: 271 ACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCV 322
C+ N ++C CP +TG C + + C P C TC G+ CV
Sbjct: 821 TCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQP--CLPPATCEEVPDGFVCV 869
Score = 45.8 bits (107), Expect = 5e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 414 DECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGE 473
D CS +PC + G C+ T F C C +TGP C + C PC ATC +
Sbjct: 809 DMCS--PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDG 865
Query: 474 FQCI 477
F C+
Sbjct: 866 FVCV 869
Score = 45.1 bits (105), Expect = 0.001
Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 15/109 (13%)
Query: 1151 PSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCP 1210
P P N + ++ G S AG C E D C PC NGGTCL N + C+CP
Sbjct: 781 PLPLDNSSQPSELGGRQSWNLTAG-----CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCP 834
Query: 1211 RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1259
G C + P C TC + G+ C F
Sbjct: 835 ANFTGPTCAQQLWCPGQP---------CLPPATCEEVPDGFVCVAEATF 874
Score = 45.1 bits (105), Expect = 0.001
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 565 VDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDN 623
V D C PDPC + G+C F C C +TG C + C QPC TC++ +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 624 AYLC 627
++C
Sbjct: 865 GFVC 868
Score = 45.1 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Query: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
C +GG C+ N HC C A +TG C + C PC ATC + G+ C A +
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATF 874
Score = 43.1 bits (100), Expect = 0.003
Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 5/69 (7%)
Query: 1352 CGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPF 1411
C C NGGTC+ C C FTGP C P G PC TCE +
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCP---GQPCLPPATCEEVPDG-- 865
Query: 1412 YRCLCPAKF 1420
+ C+ A F
Sbjct: 866 FVCVAEATF 874
Score = 43.1 bits (100), Expect = 0.003
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFS 854
C+ +PC N GTC+ + C C +TG TC L C PC C + D F
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPD--GFV 867
Query: 855 CV 856
CV
Sbjct: 868 CV 869
Score = 42.4 bits (98), Expect = 0.006
Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 12/111 (10%)
Query: 287 WTGQY--CTEDV--DECQL--MPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340
W G + C +D+ D C L P N G + G ED C+
Sbjct: 759 WGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDM------CS 812
Query: 341 SAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNP 391
CF+G TC F+C CP TG C C PC + C+ P
Sbjct: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVP 863
Score = 42.4 bits (98), Expect = 0.006
Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 6/62 (9%)
Query: 57 CQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGT 116
C + C PC N GTC V D+ C+C F+GP C L C PC T
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWN----DFHCTCPANFTGPTCAQQL--WCPGQPCLPPAT 858
Query: 117 CD 118
C+
Sbjct: 859 CE 860
Score = 42.0 bits (97), Expect = 0.008
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 9/76 (11%)
Query: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCE 515
C +PC N TCL +F C C + G C C PCL C + + F C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 516 C--------PTGFTGH 523
P F+GH
Sbjct: 870 AEATFREGPPAAFSGH 885
Score = 41.6 bits (96), Expect = 0.010
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 5/43 (11%)
Query: 21 GPRCSQP-----GETCLNGGKCEAANGTEACVCGGAFVGPRCQ 58
G RC P CLNGG C AA G C+C F G C+
Sbjct: 1167 GQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 40.4 bits (93), Expect = 0.023
Identities = 13/42 (30%), Positives = 21/42 (50%)
Query: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDV 179
C++ + C PC +GG C+ + C C GPTC ++
Sbjct: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 40.4 bits (93), Expect = 0.023
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 179 VNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGD 238
V+E P C +GGTC + C C A TGP C + + C PC TC D
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-QLWCPGQPCLPPATCEEVPD 864
Score = 39.7 bits (91), Expect = 0.038
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 530 DECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFT 588
D C+ PC NG CL N + C C +TG C + C PC +C++ F
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 589 CL 590
C+
Sbjct: 868 CV 869
Score = 39.3 bits (90), Expect = 0.050
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 9/71 (12%)
Query: 370 CHLNDACISNPCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAG 427
C D C +PC G C N + CTCP+ +TGP C+Q + PC
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFH----CTCPANFTGPTCAQ---QLWCPGQPCLPPA 857
Query: 428 KCINTLGSFEC 438
C F C
Sbjct: 858 TCEEVPDGFVC 868
Score = 39.3 bits (90), Expect = 0.050
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 1094
C PC NGG C T + C CP+ +TG C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
Score = 38.1 bits (87), Expect = 0.11
Identities = 17/49 (34%), Positives = 18/49 (36%)
Query: 29 ETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVV 77
+ C NGG C C C F GP C C PC TC V
Sbjct: 814 DPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEV 862
Score = 37.7 bits (86), Expect = 0.15
Identities = 14/37 (37%), Positives = 22/37 (59%)
Query: 1182 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHC 1218
E ++C PC +GG+C+DL ++C C R +G C
Sbjct: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 37.4 bits (85), Expect = 0.19
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 15/81 (18%)
Query: 572 PDPCHYGSCKDGVATFT-CLCRPGYTGH-------------HCETNINECSSQPCRHGGT 617
P P S + G ATF CL GH CE +C PC HGG+
Sbjct: 561 PLPAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVLLGCERR-EQCRPLPCVHGGS 619
Query: 618 CQDRDNAYLCFCLKGTTGPNC 638
C D + C C + GP C
Sbjct: 620 CVDLWTHFRCDCARPHRGPTC 640
Score = 37.4 bits (85), Expect = 0.19
Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 487 CEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDV 529
CE ++C PC+H G C+D F+C+C G C ++
Sbjct: 603 CE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 35.4 bits (80), Expect = 0.73
Identities = 11/32 (34%), Positives = 17/32 (53%)
Query: 422 PCEHAGKCINTLGSFECQCLQGYTGPRCEIDV 453
PC H G C++ F C C + + GP C ++
Sbjct: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 35.4 bits (80), Expect = 0.73
Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
Query: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCD 932
C PC +G +C T + C C A ++G C + C PC +C + + C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 933 CLPGFR 938
FR
Sbjct: 870 AEATFR 875
Score = 33.9 bits (76), Expect = 2.1
Identities = 13/31 (41%), Positives = 17/31 (54%)
Query: 185 KPGLCRHGGTCHNEVGSYRCVCRATHTGPNC 215
+P C HGG+C + +RC C H GP C
Sbjct: 610 RPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 33.9 bits (76), Expect = 2.1
Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 2/31 (6%)
Query: 1395 NPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
+PC+N GTC T + C CPA F G C
Sbjct: 814 DPCFNGGTCLVTWND--FHCTCPANFTGPTC 842
Score = 32.7 bits (73), Expect = 4.7
Identities = 15/48 (31%), Positives = 19/48 (39%), Gaps = 7/48 (14%)
Query: 330 EDCSENI-------DDCASAACFHGATCHDRVASFYCECPHGRTGLLC 370
ED EN+ + C C HG +C D F C+C G C
Sbjct: 593 EDLGENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 32.0 bits (71), Expect = 8.0
Identities = 13/40 (32%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Query: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC--DVPSVS 1100
C PC +GG C T +RC+C G C ++P+ +
Sbjct: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAAT 648
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 285 bits (728), Expect = 5e-76
Identities = 252/839 (30%), Positives = 319/839 (38%), Gaps = 236/839 (28%)
Query: 478 CMPGY--EGVHC-EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDE--- 531
C PGY G C + T+EC +GRC ++ C C G+ G C D
Sbjct: 88 CCPGYYESGDFCIPLCTEECV------HGRC---VSPDTCHCEPGWGGPDCSSGCDSDHW 138
Query: 532 ---CAST-PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPD--------PC---H 576
C++ C+NGA C P T CVC G+ G CE + C P PC H
Sbjct: 139 GPHCSNRCQCQNGALC--NPITGACVCAAGFRGWRCE---ELCAPGTHGKGCQLPCQCRH 193
Query: 577 YGSCKDGVATFTCLCRPGYTGHHCE------TNINECSSQ-PCRHGGTCQDRDNAYLCF- 628
SC CLC PGYTG +CE ++ C + PC++GGTC C
Sbjct: 194 GASCDPRAGE--CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPP 251
Query: 629 ----------CLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNIN 678
C GT G NC DC PC G D + G +C C GY G C
Sbjct: 252 GWTGAVCAQPCPPGTFGQNCS---QDC---PCHHGGQCDHVTG-QCHCTAGYMGDRCQEE 304
Query: 679 ID------ECAGN-PCHNGGTC---------EDGINGFTCR---CPEGYHDPTCLSEVNE 719
+C+ + CHNGG C E G G C+ CPEG H P C
Sbjct: 305 CPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPC-P 363
Query: 720 CNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN----------PCVNGGTCK 769
C+++ + +C C C PGWSG +C N C C NG C
Sbjct: 364 CDADNTI--SCHPVTGA--CTCQPGWSGHHC---NESCPVGYYGDGCQLPCTCQNGADCH 416
Query: 770 DMTSGYVCTCREGFSGPNCQTNINECASNP-------CLNQGTCIDDVAGYKCNCLLPYT 822
+T G CTC GF G C + P C N GTC V G C C +
Sbjct: 417 SITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC-SPVDG-SCTCKEGWQ 472
Query: 823 GATCEVVLAPCAPS-----------PCRNGGECRQSEDYESFSCVCPTGWQGQTCEV--- 868
G C + PC PS C NG C + SC C GW G TCE+
Sbjct: 473 GLDCTL---PC-PSGTWGLNCNESCTCANGAACSPIDG----SCSCTPGWLGDTCELPCP 524
Query: 869 ----DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP-------CH 917
+N C H C G C C AG++G C++ R P C
Sbjct: 525 DGTFGLNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE 582
Query: 918 NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSG 977
NGGSC+ C+C PGFRG C+ CP GF G
Sbjct: 583 NGGSCSP--EDGSCECAPGFRGPLCQR-------------------------ICPPGFYG 615
Query: 978 IHCENNTPDCTESS--CFNGGTCVDGINSFTCLCPPGFTGSYCQ------HDVNECDSQ- 1028
C P C SS C + + GI C C PGF+G+ C + +C
Sbjct: 616 HGCAQPCPLCVHSSRPCHH----ISGI----CECLPGFSGALCNQVCAGGYFGQDCAQLC 667
Query: 1029 PCLHGGTCQDGCGSYRC-----------TCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQT 1077
C + GTC GS +C CP G+ GP C H C C NG C +
Sbjct: 668 SCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC---FHACS---CHNGASC--S 719
Query: 1078 HTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH----CRC 1133
C C GWTGL+C + C A G D R+CQ C + + H C C
Sbjct: 720 AEDGACHCTPGWTGLFC---TQRCPAAF--FGKDCGRVCQ----CQNGASCDHISGKCTC 770
Query: 1134 QAGYTGSYCEDLVDECSPS----------PCQNGATCTDYLGGYSCKCVAGYHGVNCSE 1182
+ G+TG +CE C+P C N +TC G +C C G+ G+ C +
Sbjct: 771 RTGFTGQHCE---QRCAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGFKGIRCDQ 824
Score = 277 bits (708), Expect = 1e-73
Identities = 249/822 (30%), Positives = 321/822 (39%), Gaps = 228/822 (27%)
Query: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQD-------PNPC-LSTPCKNAG 72
GP CS + C NG C G ACVC F G RC++ C L C++
Sbjct: 139 GPHCSNRCQ-CQNGALCNPITG--ACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGA 195
Query: 73 TCHVVDRRGVADYACSCALGFSGPLC--LTPLDNA---C-LTNPCRNGGTCDLLTLTEYK 126
+C R G C CA G++G C L P + C L PC+NGGTC +T +
Sbjct: 196 SCD--PRAG----ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHIT---GE 246
Query: 127 CRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKP 186
C CPPGW+G C Q CPP G C QD
Sbjct: 247 CACPPGWTGAVCAQP------------------------CPPGTFGQNCSQDCP------ 276
Query: 187 GLCRHGGTCHNEVGSYRCVCRATHTGPNC--ERPY----VPCSP-SPCQNGGTCRPTGDV 239
C HGG C + G +C C A + G C E P+ CS C NGG C PT
Sbjct: 277 --CHHGGQCDHVTG--QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT--- 329
Query: 240 THECACLPGFTGQNCEENIDDCP----GNNCKNGGACVDGVNTYNCR-------CPPEWT 288
T C C PG+ G C+E + CP G C C D NT +C C P W+
Sbjct: 330 TGACECEPGYKGPRCQERL--CPEGLHGPGCTLPCPC-DADNTISCHPVTGACTCQPGWS 386
Query: 289 GQYCTEDV------DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI------ 336
G +C E D CQL P CQNG CH+ GG C C G+ GE C+ +
Sbjct: 387 GHHCNESCPVGYYGDGCQL-PCTCQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYG 443
Query: 337 DDCAS-AACFHGATCHDRVASFYCE-----------CPHGRTGLLCHLNDACISNPCNEG 384
+C+S +C +G TC S C+ CP G GL C N++C C G
Sbjct: 444 PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNC--NESC---TCANG 498
Query: 385 SNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGSFECQ 439
+ C +P++G C+C G+ G C + + G N C HA C G C
Sbjct: 499 AAC--SPIDGS--CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG--HCC 552
Query: 440 CLQGYTGPRCEIDV-------NECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCE---- 488
CL G+TG RC+ N VS C+N +C + G C C PG+ G C+
Sbjct: 553 CLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG--SCECAPGFRGPLCQRICP 610
Query: 489 --VNTDECAS--SPCLHNGRCLDKINEFQCECPTGFTGHLCQ------YDVDECAS-TPC 537
CA C+H+ R I+ CEC GF+G LC Y +CA C
Sbjct: 611 PGFYGHGCAQPCPLCVHSSRPCHHISGI-CECLPGFSGALCNQVCAGGYFGQDCAQLCSC 669
Query: 538 KNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTG 597
N C P +C C G+ G C + C PG+ G
Sbjct: 670 ANNGTC--SPIDGSCQCFPGWIGKDC------------------------SQACPPGFWG 703
Query: 598 HHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINL------DDCAS-SPC 650
C + CS C +G +C D A C C G TG C DC C
Sbjct: 704 PAC---FHACS---CHNGASCSAEDGA--CHCTPGWTGLFCTQRCPAAFFGKDCGRVCQC 755
Query: 651 DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHD 710
+G D I G +C C G+TG C C G G+ C+
Sbjct: 756 QNGASCDHISG-KCTCRTGFTGQHCE--------------QRCAPGTFGYGCQ------- 793
Query: 711 PTCLSEVNEC-NSNPCVHGACRDSLNGYKCDCDPGWSGTNCD 751
++ EC N++ C D + G C C PG+ G CD
Sbjct: 794 -----QLCECMNNSTC------DHVTG-TCYCSPGFKGIRCD 823
Score = 261 bits (667), Expect = 6e-69
Identities = 251/875 (28%), Positives = 318/875 (36%), Gaps = 253/875 (28%)
Query: 89 CALGF--SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA----- 141
C G+ SG C+ C+ C + TC C PGW G C
Sbjct: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDTC----------HCEPGWGGPDCSSGCDSDH 137
Query: 142 -DPCASN--PCANGGQCLPFEASYICH-----------CPPSFHGPTCRQDVNECGQKPG 187
P SN C NG C P + +C C P HG C Q P
Sbjct: 138 WGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGC--------QLPC 189
Query: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPS-------PCQNGGTCRPTGDVT 240
CRHG +C G C+C +TG CE P S PCQNGGTC +T
Sbjct: 190 QCRHGASCDPRAG--ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCH---HIT 244
Query: 241 HECACLPGFT-------------GQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEW 287
ECAC PG+T GQNC + DCP C +GG C D V T C C +
Sbjct: 245 GECACPPGWTGAVCAQPCPPGTFGQNCSQ---DCP---CHHGGQC-DHV-TGQCHCTAGY 296
Query: 288 TGQYCTEDVD------ECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCAS 341
G C E+ +C + C NGG C T G C C G+ G C E +
Sbjct: 297 MGDRCQEECPFGSFGFQCSQHCD-CHNGGQCSPTTGA--CECEPGYKGPRCQERL----- 348
Query: 342 AACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCP 401
CP G G C L C PC+ + +PV G CTC
Sbjct: 349 -------------------CPEGLHGPGCTL--PC---PCDADNTISCHPVTG--ACTCQ 382
Query: 402 SGYTGPACSQDV------DECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNE 455
G++G C++ D C L C++ C + G C C G+ G C +
Sbjct: 383 PGWSGHHCNESCPVGYYGDGCQLPCT-CQNGADCHSITGG--CTCAPGFMGEVCAVSCAA 439
Query: 456 CVSNP-------CQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
P C N TC G C C G++G+ C +
Sbjct: 440 GTYGPNCSSICSCNNGGTCSPVDG--SCTCKEGWQGLDCTL------------------- 478
Query: 509 INEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDI- 567
CP+G G C S C NGA C P +C CT G+ G CE+
Sbjct: 479 ------PCPSGTWGLNCN------ESCTCANGAAC--SPIDGSCSCTPGWLGDTCELPCP 524
Query: 568 ---------DECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI------NECS-SQP 611
+ CD C + D V T C C G+TG C++ CS S
Sbjct: 525 DGTFGLNCSEHCD---CSHADGCDPV-TGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCS 580
Query: 612 CRHGGTCQDRDNAYLCFCLKGTTGPNCE------INLDDCASSPC----DSGTCLDKIDG 661
C +GG+C D + C C G GP C+ CA PC S I G
Sbjct: 581 CENGGSCSPEDGS--CECAPGFRGPLCQRICPPGFYGHGCA-QPCPLCVHSSRPCHHISG 637
Query: 662 YECACEPGYTGSMCNINIDECAGN----------PCHNGGTCE---------DGINGFTC 702
C C PG++G++CN CAG C N GTC G G C
Sbjct: 638 I-CECLPGFSGALCN---QVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDC 693
Query: 703 --RCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCD------INN 754
CP G+ P C + C+ C +GA + +G C C PGW+G C
Sbjct: 694 SQACPPGFWGPACF---HACS---CHNGASCSAEDG-ACHCTPGWTGLFCTQRCPAAFFG 746
Query: 755 NEC-ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGY 813
+C C NG +C D SG CTCR GF+G +C+ C GY
Sbjct: 747 KDCGRVCQCQNGASC-DHISG-KCTCRTGFTGQHCEQR--------------CAPGTFGY 790
Query: 814 KCNCLLP-YTGATCEVVLAPCAPSPCRNGGECRQS 847
C L +TC+ V C SP G C Q+
Sbjct: 791 GCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQA 825
Score = 261 bits (666), Expect = 8e-69
Identities = 247/883 (27%), Positives = 328/883 (37%), Gaps = 233/883 (26%)
Query: 504 RCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGY--TGT 561
RC D +N F+C T H Y T + G + + + C GY +G
Sbjct: 53 RCTDILNWFKC------TRHRISY------KTAYRRGLRTMYRRRSQCC---PGYYESGD 97
Query: 562 HCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINE------CSSQ-PCRH 614
C I C + C +G C V+ TC C PG+ G C + + CS++ C++
Sbjct: 98 FC---IPLCTEE-CVHGRC---VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQN 150
Query: 615 GGTCQDRDNAYLC-----------FCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYE 663
G C A +C C GT G C++ C G D G E
Sbjct: 151 GALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQ------CRHGASCDPRAG-E 203
Query: 664 CACEPGYTGSMCNINIDECAGN----------PCHNGGTCEDGINGFTCRCPEGYHDPTC 713
C C PGYTG C + C PC NGGTC I G C CP G+ C
Sbjct: 204 CLCAPGYTGVYCE---ELCPPGSHGAHCELRCPCQNGGTCHH-ITG-ECACPPGWTGAVC 258
Query: 714 LSEV------NECNSN-PCVHGACRDSLNGYKCDCDPGWSGTNCDIN------NNECESN 760
C+ + PC HG D + G +C C G+ G C +C +
Sbjct: 259 AQPCPPGTFGQNCSQDCPCHHGGQCDHVTG-QCHCTAGYMGDRCQEECPFGSFGFQCSQH 317
Query: 761 -PCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI-------------------NECASNPC 800
C NGG C T C C G+ GP CQ + N + +P
Sbjct: 318 CDCHNGGQCSPTTGA--CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPV 375
Query: 801 LNQGTCIDDVAGYKCN--CLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCP 858
TC +G+ CN C + Y G C++ P C+NG +C C C
Sbjct: 376 TGACTCQPGWSGHHCNESCPVGYYGDGCQL------PCTCQNGADCHSITG----GCTCA 425
Query: 859 TGWQGQTCEVDINECVLSP-------CRHGASCQNTHGGYRCHCQAGYSGRNCETDID-- 909
G+ G+ C V P C +G +C G C C+ G+ G +C
Sbjct: 426 PGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSG 483
Query: 910 ----DCRPN-PCHNGGSCT--DGINTAFCDCLPGFRGTFCEEDINECASDPCRNGA---N 959
+C + C NG +C+ DG C C PG+ G CE PC +G N
Sbjct: 484 TWGLNCNESCTCANGAACSPIDGS----CSCTPGWLGDTCEL--------PCPDGTFGLN 531
Query: 960 CT---DC-----VDSYT--CTCPAGFSGIHCENNTP------DCTES-SCFNGGTCVDGI 1002
C+ DC D T C C AG++GI C++ P +C+ S SC NGG+C
Sbjct: 532 CSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPED 591
Query: 1003 NSFTC-----------LCPPGFTGSYCQHDVNEC--DSQPCLH-GGTCQ--DGCGSYRCT 1046
S C +CPPGF G C C S+PC H G C+ G C
Sbjct: 592 GSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCN 651
Query: 1047 --CPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 1104
C GY G +C L C N G C + C+C GW G C S +C
Sbjct: 652 QVCAGGYFGQDCAQLCS------CANNGTC--SPIDGSCQCFPGWIGKDC---SQACPPG 700
Query: 1105 AQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYL 1164
A C +G C + C C G+TG +C
Sbjct: 701 FWGPACFHACSCHNGASC--SAEDGACHCTPGWTGLFCTQ-------------------- 738
Query: 1165 GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1224
+C A + G +C CQNG +C + KC+C G G HCE
Sbjct: 739 -----RCPAAFFGKDCGRVCQ------CQNGASCDHISG--KCTCRTGFTGQHCE---QR 782
Query: 1225 CNPPVDPVSRSP--KCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
C P +C NN TC D V G +C C PGF G RC+
Sbjct: 783 CAPGTFGYGCQQLCECMNNSTC-DHVTG-TCYCSPGFKGIRCD 823
Score = 249 bits (636), Expect = 2e-65
Identities = 224/796 (28%), Positives = 290/796 (36%), Gaps = 205/796 (25%)
Query: 703 RCPEGYHD------PTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDIN--- 753
+C GY++ P C E CVHG C ++ C C+PGW G +C
Sbjct: 87 QCCPGYYESGDFCIPLCTEE--------CVHGRC---VSPDTCHCEPGWGGPDCSSGCDS 135
Query: 754 -------NNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ------TNINECASNPC 800
+N C+ C NG C +T C C GF G C+ T+ C
Sbjct: 136 DHWGPHCSNRCQ---CQNGALCNPITGA--CVCAAGFRGWRCEELCAPGTHGKGCQLPCQ 190
Query: 801 LNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPS-------PCRNGGECRQSEDYESF 853
G D AG +C C YTG CE + P + PC+NGG C + +
Sbjct: 191 CRHGASCDPRAG-ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCH----HITG 245
Query: 854 SCVCPTGWQGQTCEVDINECVLS-------PCRHGASCQNTHGGYRCHCQAGYSGRNCET 906
C CP GW G C PC HG C + G +CHC AGY G C+
Sbjct: 246 ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG--QCHCTAGYMGDRCQE 303
Query: 907 DID------DCRPN-PCHNGGSCTDGINTAFCDCLPGFRGTFCEEDI------NECASDP 953
+ C + CHNGG C+ T C+C PG++G C+E + + P
Sbjct: 304 ECPFGSFGFQCSQHCDCHNGGQCSP--TTGACECEPGYKGPRCQERLCPEGLHGPGCTLP 361
Query: 954 CRNGANCTDCVDSYT--CTCPAGFSGIHCENNTP----------DCTESSCFNGGTCVDG 1001
C A+ T T CTC G+SG HC + P CT C NG C
Sbjct: 362 CPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCT---CQNGADC--- 415
Query: 1002 INSFT--CLCPPGFTGSYCQ-------HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT 1052
+S T C C PGF G C + N C +GGTC GS CTC +G+
Sbjct: 416 -HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQ 472
Query: 1053 GPNCQNL-------VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAA 1105
G +C ++ +S C NG C + C C GW G C++P C
Sbjct: 473 GLDCTLPCPSGTWGLNCNESCTCANGAAC--SPIDGSCSCTPGWLGDTCELP---CPDGT 527
Query: 1106 QRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD------ECSPS-PCQNGA 1158
C H C T HC C AG+TG C+ CS S C+NG
Sbjct: 528 FGLNCSEHCDCSHADGCDPV--TGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGG 585
Query: 1159 TCTDYLGGYSCK-----------CVAGYHGVNCSEEIDECL--SHPCQN-GGTCLDLPNT 1204
+C+ G C C G++G C++ C+ S PC + G C LP
Sbjct: 586 SCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGF 645
Query: 1205 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC----------- 1253
C + G + DC ++ C NNGTC G C
Sbjct: 646 SGALCNQVCAGGYFG---QDC-------AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ 695
Query: 1254 TCPPGFVGERC--------------EGDVNECLSNPCDARGTQNC------------VQR 1287
CPPGF G C E C TQ C Q
Sbjct: 696 ACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQC 755
Query: 1288 VNDFHCE-------CRAGHTGRRCESVIN------GCKGK-PCKNGGTCAVASNTARGFI 1333
N C+ CR G TG+ CE GC+ C N TC + T
Sbjct: 756 QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGT----- 810
Query: 1334 CKCPAGFEGATCENDA 1349
C C GF+G C+ A
Sbjct: 811 CYCSPGFKGIRCDQAA 826
Score = 238 bits (608), Expect = 4e-62
Identities = 234/813 (28%), Positives = 298/813 (36%), Gaps = 192/813 (23%)
Query: 283 CPPEW-TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDD--- 338
CP + +G +C E + + C + TCH C GW G DCS D
Sbjct: 89 CPGYYESGDFCIPLCTE-ECVHGRCVSPDTCH---------CEPGWGGPDCSSGCDSDHW 138
Query: 339 ---CAS-AACFHGATCHDRVASFYCECPHGRTGLLC--------HLNDACISNPCNEGSN 386
C++ C +GA C+ + C C G G C H + C G++
Sbjct: 139 GPHCSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGAS 196
Query: 387 CDTNPVNGKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGSFECQCL 441
CD P G+ C C GYTG C + S GA+ PC++ G C + G EC C
Sbjct: 197 CD--PRAGE--CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITG--ECACP 250
Query: 442 QGYTGPRC-------EIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDEC 494
G+TG C N PC + C G QC C GY G C
Sbjct: 251 PGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG--QCHCTAGYMGDRC------- 301
Query: 495 ASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVC 554
Q ECP G G C D C NG +C P T C C
Sbjct: 302 ------------------QEECPFGSFGFQCSQHCD------CHNGGQC--SPTTGACEC 335
Query: 555 TEGYTGTHCEVDI-------DECD-PDPCHYG---SCKDGVATFTCLCRPGYTGHHCETN 603
GY G C+ + C P PC SC T C C+PG++GHHC +
Sbjct: 336 EPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHP--VTGACTCQPGWSGHHCNES 393
Query: 604 I------NECSSQ-PCRHGGTCQDRDNAYLC-----------FCLKGTTGPNCEINLDDC 645
+ C C++G C C C GT GPNC ++ C
Sbjct: 394 CPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCS-SICSC 452
Query: 646 ----ASSPCD-SGTCLDKIDGYECA--CEPGYTGSMCNIN---IDECAGNPCHNGGTCED 695
SP D S TC + G +C C G G CN + + A +P +C
Sbjct: 453 NNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTP 512
Query: 696 GINGFTCR--CPEGYHDPTCLSEVNECNSNPC----VHGACRDSLNGYKCD--CDPGWSG 747
G G TC CP+G C + +++ C H C G +CD C PG G
Sbjct: 513 GWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG 572
Query: 748 TNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI------NECAS--NP 799
NC + S C NGG+C C C GF GP CQ + CA
Sbjct: 573 PNCSV------SCSCENGGSCSPEDGS--CECAPGFRGPLCQRICPPGFYGHGCAQPCPL 624
Query: 800 CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLA------PCAP-SPCRNGGECRQSEDYES 852
C++ ++G C CL ++GA C V A CA C N G C +
Sbjct: 625 CVHSSRPCHHISGI-CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDG--- 680
Query: 853 FSCVCPTGWQGQTCEVDINECVLSP-------CRHGASCQNTHGGYRCHCQAGYSGRNCE 905
SC C GW G+ C P C +GASC G CHC G++G C
Sbjct: 681 -SCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGA--CHCTPGWTGLFCT 737
Query: 906 TDI------DDC-RPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD------ 952
DC R C NG SC D I + C C GF G CE+ CA
Sbjct: 738 QRCPAAFFGKDCGRVCQCQNGASC-DHI-SGKCTCRTGFTGQHCEQ---RCAPGTFGYGC 792
Query: 953 ----PCRNGANCTDCVDSYTCTCPAGFSGIHCE 981
C N + C TC C GF GI C+
Sbjct: 793 QQLCECMNNSTCDHVTG--TCYCSPGFKGIRCD 823
Score = 215 bits (548), Expect = 4e-55
Identities = 230/784 (29%), Positives = 286/784 (36%), Gaps = 211/784 (26%)
Query: 892 RCHCQAGY--SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINEC 949
R C GY SG C I C H G C ++ C C PG+ G C C
Sbjct: 85 RSQCCPGYYESGDFC---IPLCTEECVH--GRC---VSPDTCHCEPGWGGPDCSSG---C 133
Query: 950 ASD----------PCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS-------C 992
SD C+NGA C + C C AGF G CE T C
Sbjct: 134 DSDHWGPHCSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEELCAPGTHGKGCQLPCQC 191
Query: 993 FNGGTCVDGINSFTCLCPPGFTGSYCQ-------HDVNECDSQ-PCLHGGTCQDGCGSYR 1044
+G +C CLC PG+TG YC+ H + C+ + PC +GGTC G
Sbjct: 192 RHGASCDPRAGE--CLCAPGYTGVYCEELCPPGSHGAH-CELRCPCQNGGTCHHITG--E 246
Query: 1045 CTCPQGYTGPNC----------QNLVHWCDSSPCKNGGKCWQTHTQYRC----------- 1083
C CP G+TG C QN C PC +GG+C Q C
Sbjct: 247 CACPPGWTGAVCAQPCPPGTFGQNCSQDC---PCHHGGQCDHVTGQCHCTAGYMGDRCQE 303
Query: 1084 ECPSGWTGL------------YCDVPSVSCEVAAQRQGVDV-ARLCQ---HGGLCV---- 1123
ECP G G C + +CE +G RLC HG C
Sbjct: 304 ECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCP 363
Query: 1124 -DAGNTHHCR-------CQAGYTGSYCEDLV------DECS-PSPCQNGATCTDYLGGYS 1168
DA NT C CQ G++G +C + D C P CQNGA C GG +
Sbjct: 364 CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCT 423
Query: 1169 C-----------KCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
C C AG +G NCS C NGGTC P C+C G QG+
Sbjct: 424 CAPGFMGEVCAVSCAAGTYGPNCSSICS------CNNGGTC--SPVDGSCTCKEGWQGLD 475
Query: 1218 CEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----GDVNECL 1272
C + ++ + S C N C G SC+C PG++G+ CE G
Sbjct: 476 CTLPCPSGTWGLN-CNESCTCANGAACSPIDG--SCSCTPGWLGDTCELPCPDGTFGLNC 532
Query: 1273 SNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKP-------CKNGGTCAVA 1325
S CD C HC C AG TG RC+S + P C+NGG+C+
Sbjct: 533 SEHCDCSHADGCDPVTG--HCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPE 590
Query: 1326 SNTA------RGFICK--CPAGFEGATCENDARTC--GSLRCLNGGTCISGPRSPTCLCL 1375
+ RG +C+ CP GF G C C S C + ISG C CL
Sbjct: 591 DGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHH----ISG----ICECL 642
Query: 1376 GPFTGPECQFPASSPCLGGN---------PCYNQGTCEPTSESPFYRCLCPAKFNGLLCH 1426
F+G C + C GG C N GTC P S C C
Sbjct: 643 PGFSGALC----NQVCAGGYFGQDCAQLCSCANNGTCSPIDGS----CQC---------- 684
Query: 1427 ILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHA-CGWDGGDCSLNFND 1485
F G G+D +AC P A CS C+N A C + G C
Sbjct: 685 -----FPGWIGKD-----CSQACP-PGFWGPACFHACS--CHNGASCSAEDGACHCTPGW 731
Query: 1486 PWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHC 1545
CTQ +C F C C +G C G+C C+ F+ HC
Sbjct: 732 TGLFCTQ--RCPAAFFGKDCGRVCQCQ----NGASCDHISGKCT------CRTGFTGQHC 779
Query: 1546 DQGC 1549
+Q C
Sbjct: 780 EQRC 783
Score = 112 bits (281), Expect = 4e-24
Identities = 89/274 (32%), Positives = 116/274 (42%), Gaps = 59/274 (21%)
Query: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPC------LSTPCK----N 70
GP CS +C NGG C +G+ C C F GP CQ P + PC +
Sbjct: 572 GPNCSVSC-SCENGGSCSPEDGS--CECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHS 628
Query: 71 AGTCHVVDRRGVADYACSCALGFSGPLCLTPL-------DNACLTNPCRNGGTCDLLTLT 123
+ CH + G+ C C GFSG LC D A L + C N GTC +
Sbjct: 629 SRPCHHIS--GI----CECLPGFSGALCNQVCAGGYFGQDCAQLCS-CANNGTCSPI--- 678
Query: 124 EYKCRCPPGWSGKSCQQADPCA--------SNPCANGGQCLPFEASYICHCPPSFHGPTC 175
+ C+C PGW GK C QA P + C NG C + + CHC P + G C
Sbjct: 679 DGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGA--CHCTPGWTGLFC 736
Query: 176 RQDV------NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP------CS 223
Q +CG + C++G +C + G +C CR TG +CE+ P C
Sbjct: 737 TQRCPAAFFGKDCG-RVCQCQNGASCDHISG--KCTCRTGFTGQHCEQRCAPGTFGYGCQ 793
Query: 224 P-SPCQNGGTCRPTGDVTHECACLPGFTGQNCEE 256
C N TC VT C C PGF G C++
Sbjct: 794 QLCECMNNSTC---DHVTGTCYCSPGFKGIRCDQ 824
Score = 52.0 bits (123), Expect = 7e-06
Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 34/139 (24%)
Query: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLS--------TPCKNAG 72
GP C +C NG C A +G AC C + G C P C+N
Sbjct: 703 GPACFHAC-SCHNGASCSAEDG--ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGA 759
Query: 73 TCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNP----------CRNGGTCDLLTL 122
+C + + C+C GF+G C + C C N TCD +T
Sbjct: 760 SCDHISGK------CTCRTGFTGQHC----EQRCAPGTFGYGCQQLCECMNNSTCDHVTG 809
Query: 123 TEYKCRCPPGWSGKSCQQA 141
T C C PG+ G C QA
Sbjct: 810 T---CYCSPGFKGIRCDQA 825
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 282 bits (722), Expect = 3e-75
Identities = 237/788 (30%), Positives = 305/788 (38%), Gaps = 171/788 (21%)
Query: 166 CPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPY---VPC 222
CP S T + DV LC G ++ C C GP C P +P
Sbjct: 126 CPASAQAGTGQTDVRT------LCSLHGVF--DLSRCTCSCEPGWGGPTCSDPTDAEIPP 177
Query: 223 SPSPCQNGGT---CRPTGD-VTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT 278
S P +G C G V C C PG+TG +C CPG+ C+ G CV GV
Sbjct: 178 SSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC--GWPSCPGD-CQGRGRCVQGV-- 232
Query: 279 YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDD 338
C C ++G C++ + P C G C G CVC G+TG+DC
Sbjct: 233 --CVCRAGFSGPDCSQ-----RSCPRGCSQRGRCE----GGRCVCDPGYTGDDCGMR--- 278
Query: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAIC 398
CP G C++ C+ NG+ C
Sbjct: 279 ---------------------SCPRG----------------CSQRGRCE----NGR--C 295
Query: 399 TCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVS 458
C GYTG C V C G C G+C + C C GYTG C C
Sbjct: 296 VCNPGYTGEDCG--VRSCPRG---CSQRGRCKDG----RCVCDPGYTGEDC--GTRSCPW 344
Query: 459 NPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPT 518
+ C C+D +C+C PGY G C T C GRC D +C C T
Sbjct: 345 D-CGEGGRCVDG----RCVCWPGYTGEDCSTRT---CPRDCRGRGRCEDG----ECICDT 392
Query: 519 GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 578
G++G C V C C +C DG CVC GYTGT C C D G
Sbjct: 393 GYSGDDC--GVRSCPG-DCNQRGRCEDG----RCVCWPGYTGTDC--GSRACPRDCRGRG 443
Query: 579 SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
C++GV C+C GY+G C + C CR G C+ + C C G TG +C
Sbjct: 444 RCENGV----CVCNAGYSGEDC--GVRSCPGD-CRGRGRCE----SGRCMCWPGYTGRDC 492
Query: 639 EINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGIN 698
C G C+D C C PG+TG C C G+ C G CEDG+
Sbjct: 493 GTRA--CPGDCRGRGRCVDG----RCVCNPGFTGEDCGSR--RCPGD-CRGHGLCEDGV- 542
Query: 699 GFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECE 758
C C GY C C G C D +C C+ G+SG +C + +C
Sbjct: 543 ---CVCDAGYSGEDC--STRSCPGGCRGRGQCLDG----RCVCEDGYSGEDCGV--RQC- 590
Query: 759 SNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL 818
N C G C+D VC C EG+ +C +I C SN C +G C + +C C
Sbjct: 591 PNDCSQHGVCQD----GVCICWEGYVSEDC--SIRTCPSN-CHGRGRCEEG----RCLCD 639
Query: 819 LPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPC 878
YTG TC + P+ CR G C Q C+C G+ G+ C + E S C
Sbjct: 640 PGYTGPTCATRM---CPADCRGRGRCVQG------VCLCHVGYGGEDCGQE--EPPASAC 688
Query: 879 RHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFR 938
G + +C C G+ G +C I C P C G C DG C C G+
Sbjct: 689 PGGCGPRELCRAGQCVCVEGFRGPDCA--IQTC-PGDCRGRGECHDG----SCVCKDGYA 741
Query: 939 GTFCEEDI 946
G C E++
Sbjct: 742 GEDCGEEV 749
Score = 266 bits (679), Expect = 3e-70
Identities = 209/717 (29%), Positives = 282/717 (39%), Gaps = 129/717 (17%)
Query: 395 KAICTCPSGYTGPACSQDVDECSLGANP----------CEHAGKCINTLGSFECQCLQGY 444
+ C+C G+ GP CS D ++P C G+C+ C C GY
Sbjct: 153 RCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRG----RCVCFPGY 208
Query: 445 TGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGR 504
TGP C C + CQ C+ + C+C G+ G C + C GR
Sbjct: 209 TGPSCGWP--SCPGD-CQGRGRCVQGV----CVCRAGFSGPDC---SQRSCPRGCSQRGR 258
Query: 505 CLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
C +C C G+TG D+C C G CVC GYTG C
Sbjct: 259 C----EGGRCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDC- 306
Query: 565 VDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNA 624
+ C G CKDG C+C PGYTG C T C GG C D
Sbjct: 307 -GVRSCPRGCSQRGRCKDG----RCVCDPGYTGEDCGT---RSCPWDCGEGGRCVDG--- 355
Query: 625 YLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAG 684
C C G TG +C C G C D EC C+ GY+G C + C G
Sbjct: 356 -RCVCWPGYTGEDCSTR--TCPRDCRGRGRCEDG----ECICDTGYSGDDCGVR--SCPG 406
Query: 685 NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744
+ C+ G CEDG C C GY C S C + G C + + C C+ G
Sbjct: 407 D-CNQRGRCEDG----RCVCWPGYTGTDCGSRA--CPRDCRGRGRCENGV----CVCNAG 455
Query: 745 WSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQG 804
+SG +C + + C + C G C+ SG C C G++G +C T C +G
Sbjct: 456 YSGEDCGVRS--CPGD-CRGRGRCE---SGR-CMCWPGYTGRDCGT---RACPGDCRGRG 505
Query: 805 TCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQ 864
C+D +C C +TG C + P CR G C E CVC G+ G+
Sbjct: 506 RCVDG----RCVCNPGFTGEDCG---SRRCPGDCRGHGLC------EDGVCVCDAGYSGE 552
Query: 865 TCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTD 924
C C CR C + RC C+ GYSG +C + C PN C G C D
Sbjct: 553 DCST--RSCP-GGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQD 602
Query: 925 GINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNT 984
G+ C C G+ C I C S+ C C + C C G++G C
Sbjct: 603 GV----CICWEGYVSEDC--SIRTCPSN-CHGRGRC----EEGRCLCDPGYTGPTCATR- 650
Query: 985 PDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYR 1044
+ C G CV G+ CLC G+ G C + E + C G ++ C + +
Sbjct: 651 --MCPADCRGRGRCVQGV----CLCHVGYGGEDCGQE--EPPASACPGGCGPRELCRAGQ 702
Query: 1045 CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC--DVPSV 1099
C C +G+ GP+C + C C+ G+C C C G+ G C +VP++
Sbjct: 703 CVCVEGFRGPDC--AIQTCPGD-CRGRGECHDG----SCVCKDGYAGEDCGEEVPTI 752
Score = 260 bits (665), Expect = 1e-68
Identities = 212/715 (29%), Positives = 281/715 (39%), Gaps = 138/715 (19%)
Query: 87 CSCALGFSGPLCLTPLD-NACLTNPCRNGGTC-----DLLTLTEYKCRCPPGWSGKSCQQ 140
CSC G+ GP C P D ++P G+C D +C C PG++G SC
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
Query: 141 ADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVG 200
P C G+C+ +C C F GP C Q C P C G C
Sbjct: 214 GWPSCPGDCQGRGRCV----QGVCVCRAGFSGPDCSQ--RSC---PRGCSQRGRCEGG-- 262
Query: 201 SYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDD 260
RCVC +TG +C + P C G C C C PG+TG++C +
Sbjct: 263 --RCVCDPGYTGDDCG---MRSCPRGCSQRGRCE-----NGRCVCNPGYTGEDC--GVRS 310
Query: 261 CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYN 320
CP C G C DG C C P +TG+ C + P C GG C +
Sbjct: 311 CP-RGCSQRGRCKDG----RCVCDPGYTGEDC-----GTRSCPWDCGEGGRCVDG----R 356
Query: 321 CVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNP 380
CVC G+TGEDCS + C R C C G +G C +
Sbjct: 357 CVCWPGYTGEDCS-------TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSC--PGD 407
Query: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC 440
CN+ C+ +G+ C C GYTG C C C G+C N + C C
Sbjct: 408 CNQRGRCE----DGR--CVCWPGYTGTDCGSRA--C---PRDCRGRGRCENGV----CVC 452
Query: 441 LQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCL 500
GY+G C + C D + +C+C PGY G C T C C
Sbjct: 453 NAGYSGEDCGV-------RSCPGDCRGRGRCESGRCMCWPGYTGRDC--GTRACPGD-CR 502
Query: 501 HNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAK----CLDGPNTYTCVCTE 556
GRC+D +C C GFTG ++C S C + C DG CVC
Sbjct: 503 GRGRCVDG----RCVCNPGFTG-------EDCGSRRCPGDCRGHGLCEDG----VCVCDA 547
Query: 557 GYTGTHCEVDIDECDPDPCH-YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHG 615
GY+G C P C G C DG C+C GY+G C + +C + C
Sbjct: 548 GYSGEDCST---RSCPGGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQCPND-CSQH 597
Query: 616 GTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMC 675
G CQD +C C +G +C I C S+ G C + C C+PGYTG C
Sbjct: 598 GVCQDG----VCICWEGYVSEDCSIR--TCPSNCHGRGRC----EEGRCLCDPGYTGPTC 647
Query: 676 NINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGAC--RDS 733
+ C + C G C G+ C C GY C E ++ P G C R+
Sbjct: 648 ATRM--CPAD-CRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASACP---GGCGPREL 697
Query: 734 LNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNC 788
+C C G+ G +C I C + C G C D + C C++G++G +C
Sbjct: 698 CRAGQCVCVEGFRGPDCAIQT--CPGD-CRGRGECHDGS----CVCKDGYAGEDC 745
Score = 253 bits (645), Expect = 2e-66
Identities = 234/814 (28%), Positives = 302/814 (37%), Gaps = 176/814 (21%)
Query: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECV 457
C CP G P + +V + E K + QC TG C
Sbjct: 85 CGCPPGTEPPVLASEVQALRVRLEILEELVKGLKE------QC----TGGCCPASAQ--- 131
Query: 458 SNPCQNDATCLDQI-GEFQ-----CICMPGYEGVHCEVNTDE--CASSPCLHNGRCLDKI 509
+ Q D L + G F C C PG+ G C TD SSP +G C D
Sbjct: 132 AGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDD- 190
Query: 510 NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
C + +C+ G CVC GYTG C
Sbjct: 191 ---------------------------CNDQGRCVRG----RCVCFPGYTGPSC--GWPS 217
Query: 570 CDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFC 629
C D G C GV C+CR G++G +CS + C G + + R C C
Sbjct: 218 CPGDCQGRGRCVQGV----CVCRAGFSGP-------DCSQRSCPRGCSQRGRCEGGRCVC 266
Query: 630 LKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHN 689
G TG +C + C G C + C C PGYTG C + C
Sbjct: 267 DPGYTGDDC--GMRSCPRGCSQRGRC----ENGRCVCNPGYTGEDCGVR---SCPRGCSQ 317
Query: 690 GGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTN 749
G C+DG C C GY C C + G C D +C C PG++G +
Sbjct: 318 RGRCKDG----RCVCDPGYTGEDC--GTRSCPWDCGEGGRCVDG----RCVCWPGYTGED 367
Query: 750 CDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDD 809
C + C + C G C+D C C G+SG +C + C + C +G C D
Sbjct: 368 C--STRTCPRD-CRGRGRCEDGE----CICDTGYSGDDC--GVRSCPGD-CNQRGRCEDG 417
Query: 810 VAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVD 869
+C C YTG C + P CR G C E+ CVC G+ G+ C V
Sbjct: 418 ----RCVCWPGYTGTDCG---SRACPRDCRGRGRC------ENGVCVCNAGYSGEDCGV- 463
Query: 870 INECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTA 929
C CR C++ RC C GY+GR+C T C P C G C DG
Sbjct: 464 -RSCP-GDCRGRGRCESG----RCMCWPGYTGRDCGTRA--C-PGDCRGRGRCVDGR--- 511
Query: 930 FCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTE 989
C C PGF G C C D CR C D V C C AG+SG C +T C
Sbjct: 512 -CVCNPGFTGEDCGS--RRCPGD-CRGHGLCEDGV----CVCDAGYSGEDC--STRSCP- 560
Query: 990 SSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQ 1049
C G C+DG C+C G++G C V +C + C G CQDG C C +
Sbjct: 561 GGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQCPND-CSQHGVCQDGV----CICWE 609
Query: 1050 GYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQG 1109
GY +C + C S+ C G+C + RC C G+TG C + + +
Sbjct: 610 GYVSEDCS--IRTCPSN-CHGRGRC----EEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662
Query: 1110 VDVARLCQHGGLCVDAGNTH-------------------HCRCQAGYTGSYCEDLVDECS 1150
V LC G D G C C G+ G C + C
Sbjct: 663 VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCA--IQTC- 719
Query: 1151 PSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
P C+ C D SC C GY G +C EE+
Sbjct: 720 PGDCRGRGECHDG----SCVCKDGYAGEDCGEEV 749
Score = 244 bits (622), Expect = 1e-63
Identities = 213/729 (29%), Positives = 266/729 (36%), Gaps = 145/729 (19%)
Query: 551 TCVCTEGYTGTHCEVDID-ECDPD--PCHYGSCKDGV------ATFTCLCRPGYTGHHCE 601
TC C G+ G C D E P P GSC D C+C PGYTG C
Sbjct: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG 214
Query: 602 TNINECSSQPCRHGGTCQDRDNAY--LCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKI 659
S P G CQ R +C C G +GP+C C G C
Sbjct: 215 W-----PSCP----GDCQGRGRCVQGVCVCRAGFSGPDCSQR--SCPRGCSQRGRC---- 259
Query: 660 DGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNE 719
+G C C+PGYTG C + C G CE+G C C GY C V
Sbjct: 260 EGGRCVCDPGYTGDDCGMR---SCPRGCSQRGRCENG----RCVCNPGYTGEDC--GVRS 310
Query: 720 CNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTC 779
C G C+D +C CDPG++G +C + + C GG C D C C
Sbjct: 311 CPRGCSQRGRCKDG----RCVCDPGYTGEDCGTRSCPWD---CGEGGRCVDGR----CVC 359
Query: 780 REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
G++G +C T C +G C D +C C Y+G C V P
Sbjct: 360 WPGYTGEDCSTRT---CPRDCRGRGRCEDG----ECICDTGYSGDDCGVRSCP------- 405
Query: 840 NGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGY 899
G+C Q E CVC G+ G C + CR C+N C C AGY
Sbjct: 406 --GDCNQRGRCEDGRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV----CVCNAGY 456
Query: 900 SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGAN 959
SG +C + C P C G C G C C PG+ G C C D CR
Sbjct: 457 SGEDC--GVRSC-PGDCRGRGRCESGR----CMCWPGYTGRDC--GTRACPGD-CRGRGR 506
Query: 960 CTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ 1019
C D C C GF+G C + C G C DG+ C+C G++G C
Sbjct: 507 CVDG----RCVCNPGFTGEDCGSRR---CPGDCRGHGLCEDGV----CVCDAGYSGEDCS 555
Query: 1020 HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHT 1079
C C G C DG RC C GY+G +C V C + C G C
Sbjct: 556 --TRSCPGG-CRGRGQCLDG----RCVCEDGYSGEDCG--VRQCPND-CSQHGVCQDGV- 604
Query: 1080 QYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTG 1139
C C G+ C + + C G C + C C GYTG
Sbjct: 605 ---CICWEGYVSEDCSIRTCPSN-------------CHGRGRCEEG----RCLCDPGYTG 644
Query: 1140 SYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCL 1199
C P+ C+ C + C C GY G +C +E E + C G
Sbjct: 645 PTC---ATRMCPADCRGRGRCVQGV----CLCHVGYGGEDCGQE--EPPASACPGGCGPR 695
Query: 1200 DLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1259
+L +C C G +G C I C P D C G C D SC C G+
Sbjct: 696 ELCRAGQCVCVEGFRGPDCAIQT--C--PGD-------CRGRGECHDG----SCVCKDGY 740
Query: 1260 VGERCEGDV 1268
GE C +V
Sbjct: 741 AGEDCGEEV 749
Score = 242 bits (618), Expect = 3e-63
Identities = 220/739 (29%), Positives = 283/739 (38%), Gaps = 162/739 (21%)
Query: 701 TCRCPEGYHDPTCLSEVNE---CNSNPCVHGACRDSLNGY------KCDCDPGWSGTNCD 751
TC C G+ PTC + +S P G+C D N +C C PG++G +C
Sbjct: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG 214
Query: 752 INN--NECESNP-CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCID 808
+ +C+ CV G VC CR GFSGP+C C +G C
Sbjct: 215 WPSCPGDCQGRGRCVQG----------VCVCRAGFSGPDCS---QRSCPRGCSQRGRC-- 259
Query: 809 DVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEV 868
G +C C YTG C + P C G C E+ CVC G+ G+ C V
Sbjct: 260 --EGGRCVCDPGYTGDDCGM---RSCPRGCSQRGRC------ENGRCVCNPGYTGEDCGV 308
Query: 869 DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINT 928
C G S + RC C GY+G +C T C P C GG C DG
Sbjct: 309 -------RSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR--SC-PWDCGEGGRCVDGR-- 356
Query: 929 AFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCT 988
C C PG+ G C C D CR C D C C G+SG C C
Sbjct: 357 --CVCWPGYTGEDCST--RTCPRD-CRGRGRCEDG----ECICDTGYSGDDC--GVRSCP 405
Query: 989 ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCP 1048
C G C DG C+C PG+TG+ C + + C G C++G C C
Sbjct: 406 -GDCNQRGRCEDG----RCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV----CVCN 453
Query: 1049 QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQ 1108
GY+G +C V C C+ G+C RC C G+TG C + +
Sbjct: 454 AGYSGEDCG--VRSCPGD-CRGRGRC----ESGRCMCWPGYTGRDCGTRACPGD------ 500
Query: 1109 GVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYS 1168
C+ G CVD C C G+TG ED P C+ C D +
Sbjct: 501 -------CRGRGRCVDG----RCVCNPGFTG---EDCGSRRCPGDCRGHGLCEDGV---- 542
Query: 1169 CKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCN 1226
C C AGY G +CS S P C+ G CLD +C C G G C V C
Sbjct: 543 CVCDAGYSGEDCSTR-----SCPGGCRGRGQCLD----GRCVCEDGYSGEDC--GVRQC- 590
Query: 1227 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQ 1286
P D C +G C D V C C G+V E C + C SN C RG
Sbjct: 591 -PND-------CSQHGVCQDGV----CICWEGYVSEDCS--IRTCPSN-CHGRG------ 629
Query: 1287 RVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
R + C C G+TG C + + C C+ G C +C C G+ G C
Sbjct: 630 RCEEGRCLCDPGYTGPTCATRM--CPAD-CRGRGRCVQG-------VCLCHVGYGGEDCG 679
Query: 1347 NDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPT 1406
+ + C G R+ C+C+ F GP+C A C G C +G C
Sbjct: 680 QEEPPASA--CPGGCGPRELCRAGQCVCVEGFRGPDC---AIQTCPG--DCRGRGECHDG 732
Query: 1407 SESPFYRCLCPAKFNGLLC 1425
S C+C + G C
Sbjct: 733 S------CVCKDGYAGEDC 745
Score = 225 bits (573), Expect = 5e-58
Identities = 204/742 (27%), Positives = 277/742 (37%), Gaps = 178/742 (23%)
Query: 15 PALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCL---STPCKNA 71
PA A G + C G + + T C C + GP C DP S+P +
Sbjct: 127 PASAQAGTGQTDVRTLCSLHGVFDLSRCT--CSCEPGWGGPTCSDPTDAEIPPSSPPSAS 184
Query: 72 GTC--HVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC 129
G+C D+ C C G++GP C P +C C+ G C + C C
Sbjct: 185 GSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWP---SC-PGDCQGRGRC-----VQGVCVC 235
Query: 130 PPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLC 189
G+SG C Q C+ G+C C C P + G C + C P C
Sbjct: 236 RAGFSGPDCSQRS--CPRGCSQRGRC----EGGRCVCDPGYTGDDC--GMRSC---PRGC 284
Query: 190 RHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGF 249
G C N RCVC +TG +C V P C G C+ C C PG+
Sbjct: 285 SQRGRCENG----RCVCNPGYTGEDCG---VRSCPRGCSQRGRCKDG-----RCVCDPGY 332
Query: 250 TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNG 309
TG++C CP + C GG CVDG C C P +TG+ C+ + P C+
Sbjct: 333 TGEDCGTR--SCPWD-CGEGGRCVDG----RCVCWPGYTGEDCST-----RTCPRDCRGR 380
Query: 310 GTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLL 369
G C + C+C G++G+DC + C C C D C C G TG
Sbjct: 381 GRCEDGE----CICDTGYSGDDCG--VRSCPGD-CNQRGRCEDG----RCVCWPGYTGTD 429
Query: 370 CHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC 429
C + AC C C+ NG +C C +GY+G C V C C G+C
Sbjct: 430 CG-SRAC-PRDCRGRGRCE----NG--VCVCNAGYSGEDCG--VRSCP---GDCRGRGRC 476
Query: 430 INTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEV 489
S C C GYTG +C + C D + + +C+C PG+ G C
Sbjct: 477 ----ESGRCMCWPGYTG-------RDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDC-- 523
Query: 490 NTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAK----CLD 545
+ C C +G C D + C C G++G ++C++ C G + CLD
Sbjct: 524 GSRRCPGD-CRGHGLCEDGV----CVCDAGYSG-------EDCSTRSCPGGCRGRGQCLD 571
Query: 546 GPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATF------------------ 587
G CVC +GY+G C V +C D +G C+DGV
Sbjct: 572 G----RCVCEDGYSGEDCGVR--QCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNC 625
Query: 588 ---------TCLCRPGYTGHHCETNINECSSQPCRHGGTC-------------------- 618
CLC PGYTG C T + C + CR G C
Sbjct: 626 HGRGRCEEGRCLCDPGYTGPTCATRM--CPAD-CRGRGRCVQGVCLCHVGYGGEDCGQEE 682
Query: 619 ------------QDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECAC 666
++ A C C++G GP+C I C G C D C C
Sbjct: 683 PPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQT--CPGDCRGRGECHDG----SCVC 736
Query: 667 EPGYTGSMCNINIDECAGNPCH 688
+ GY G C + G H
Sbjct: 737 KDGYAGEDCGEEVPTIEGMRMH 758
Score = 185 bits (470), Expect = 4e-46
Identities = 212/767 (27%), Positives = 263/767 (34%), Gaps = 199/767 (25%)
Query: 857 CPTGWQGQTCEVDINE-CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCE--TDIDDCRP 913
CP Q T + D+ C L + C C C+ G+ G C TD +
Sbjct: 126 CPASAQAGTGQTDVRTLCSLHGVFDLSRCT-------CSCEPGWGGPTCSDPTDAEIPPS 178
Query: 914 NPCHNGGSCTDGINT------AFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSY 967
+P GSC D N C C PG+ G C C D C+ C V
Sbjct: 179 SPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWP--SCPGD-CQGRGRCVQGV--- 232
Query: 968 TCTCPAGFSGIHCENNTPDCTESSCFNG----GTCVDGINSFTCLCPPGFTGSYCQHDVN 1023
C C AGFSG PDC++ SC G G C G C+C PG+TG +
Sbjct: 233 -CVCRAGFSG-------PDCSQRSCPRGCSQRGRCEGG----RCVCDPGYTG-------D 273
Query: 1024 ECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRC 1083
+C + C G + + C + RC C GYTG +C V C C G+C RC
Sbjct: 274 DCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG--VRSCPRG-CSQRGRC----KDGRC 326
Query: 1084 ECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143
C G+TG C S + C GG CVD C C GYTG E
Sbjct: 327 VCDPGYTGEDCGTRSCPWD-------------CGEGGRCVDG----RCVCWPGYTG---E 366
Query: 1144 DLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNG----GTCL 1199
D P C+ C D C C GY G +C + C Q G G C+
Sbjct: 367 DCSTRTCPRDCRGRGRCEDG----ECICDTGYSGDDCG--VRSCPGDCNQRGRCEDGRCV 420
Query: 1200 DLP-----NTYKCSCPRGTQGV-HCEINVDDCNPPVDP----VSRSP-KCFNNGTCVDQV 1248
P + +CPR +G CE V CN V P C G C
Sbjct: 421 CWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESG- 479
Query: 1249 GGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI 1308
C C PG+ G C C P D RG CV D C C G TG C S
Sbjct: 480 ---RCMCWPGYTGRDC--GTRAC---PGDCRGRGRCV----DGRCVCNPGFTGEDCGS-- 525
Query: 1309 NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPR 1368
C G C+ G C +C C AG+ G C R+C C G C+ G
Sbjct: 526 RRCPGD-CRGHGLCEDG-------VCVCDAGYSGEDCST--RSCPG-GCRGRGQCLDG-- 572
Query: 1369 SPTCLCLGPFTGPEC---QFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
C+C ++G +C Q P N C G C+ C+C + C
Sbjct: 573 --RCVCEDGYSGEDCGVRQCP--------NDCSQHGVCQDGV------CICWEGYVSEDC 616
Query: 1426 HILDY-SFGGGAGRDIPPPLIEEACELPECQEDAG-------NKVCSLQCNNHA------ 1471
I S G GR CE C D G ++C C
Sbjct: 617 SIRTCPSNCHGRGR----------CEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGV 666
Query: 1472 ----CGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQ--CNSAGCL----FDGFDC 1521
G+ G DC P C G C + C + C+ F G DC
Sbjct: 667 CLCHVGYGGEDCGQE-EPPASACP-----------GGCGPRELCRAGQCVCVEGFRGPDC 714
Query: 1522 --QRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVP 1566
Q G C G C G + + G DC E VP
Sbjct: 715 AIQTCPGDCR-----------GRGECHDGSCVCKDGYAGEDCGEEVP 750
Score = 180 bits (457), Expect = 1e-44
Identities = 198/737 (26%), Positives = 254/737 (34%), Gaps = 157/737 (21%)
Query: 852 SFSCVCPTGWQGQTCEVDINEC-----VLSPCRHGASCQNTHGGYRCHCQAGYSGRNCET 906
S C CP G + ++ +L G Q T G QAG +T
Sbjct: 82 STGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTG----QT 137
Query: 907 DIDD-CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINE---CASDPCRNGANCTD 962
D+ C + + CT C C PG+ G C + + +S P +G+ D
Sbjct: 138 DVRTLCSLHGVFDLSRCT-------CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDD 190
Query: 963 CVDSYTCT-----CPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSY 1017
C D C C G++G C P C C G CV G+ C+C GF+G
Sbjct: 191 CNDQGRCVRGRCVCFPGYTGPSC--GWPSCP-GDCQGRGRCVQGV----CVCRAGFSGP- 242
Query: 1018 CQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQT 1077
+C + C G + + C RC C GYTG +C + C C G+C
Sbjct: 243 ------DCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG--MRSCPRG-CSQRGRC--- 290
Query: 1078 HTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGY 1137
RC C G+TG C V S R C G C D C C GY
Sbjct: 291 -ENGRCVCNPGYTGEDCGVRS-------------CPRGCSQRGRCKDG----RCVCDPGY 332
Query: 1138 TGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGT 1197
TG ED P C G C D C C GY G +CS C+ G
Sbjct: 333 TG---EDCGTRSCPWDCGEGGRCVD----GRCVCWPGYTGEDCS---TRTCPRDCRGRGR 382
Query: 1198 CLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPP 1257
C D +C C G G DDC P C G C D C C P
Sbjct: 383 CED----GECICDTGYSG-------DDCGVRSCP----GDCNQRGRCEDG----RCVCWP 423
Query: 1258 GFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
G+ G C C P D RG C V C C AG++G C + C G C+
Sbjct: 424 GYTGTDCGS--RAC---PRDCRGRGRCENGV----CVCNAGYSGEDCG--VRSCPG-DCR 471
Query: 1318 NGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGP 1377
G C C C G+ G C R C C G C+ G C+C
Sbjct: 472 GRGRCESGR-------CMCWPGYTGRDC--GTRACPG-DCRGRGRCVDG----RCVCNPG 517
Query: 1378 FTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFG-GGA 1436
FTG +C S C G C G CE C+C A ++G C G G
Sbjct: 518 FTGEDC---GSRRCPG--DCRGHGLCEDGV------CVCDAGYSGEDCSTRSCPGGCRGR 566
Query: 1437 GRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQC 1496
G+ + + CE ED G + C C+ H DG C
Sbjct: 567 GQCLDGRCV---CEDGYSGEDCGVRQCPNDCSQHGVCQDG----------------VCIC 607
Query: 1497 WKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLY------DQYC-KDHFSDGHCDQGC 1549
W+ + C + + C G C+ C+P Y + C D G C QG
Sbjct: 608 WEGYVSEDCSIRTCPSNCHGRG-RCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGV 666
Query: 1550 NSAECEWDGLDCAEHVP 1566
+ G DC + P
Sbjct: 667 CLCHVGYGGEDCGQEEP 683
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 281 bits (718), Expect = 8e-75
Identities = 146/374 (39%), Positives = 189/374 (50%), Gaps = 25/374 (6%)
Query: 726 VHGACRDSLN-GYKCDCDPGWSGTNCDINNNECESNPCVNGG-TCKDMTSGYVCTCREGF 783
+H + R L Y+ CD + G C + C G TC + C G+
Sbjct: 163 LHSSGRTDLKYSYRFVCDEHYYGEGCSVF---CRPRDDAFGHFTCGERGEK---VCNPGW 216
Query: 784 SGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGE 843
GP C I C G C D G +C C + + G C+ C P G
Sbjct: 217 KGPYCTEPI--CLPGCDEQHGFC--DKPG-ECKCRVGWQGRYCD----ECIRYPGCLHGT 267
Query: 844 CRQSEDYESFSCVCPTGWQGQTCEVDINECVL-SPCRHGASCQNT-HGGYRCHCQAGYSG 901
C+Q + C C GW G C D+N C PC++GA+C NT G Y C C+ GY+G
Sbjct: 268 CQQP-----WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322
Query: 902 RNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCT 961
CE ID+C P+PC NGGSCTD N+ C C PGF G CE CA PC NG C+
Sbjct: 323 ATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCS 382
Query: 962 DCVDS-YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH 1020
D D Y+C CP G+SG +CE C+ S C NG CVD +++ C C GF+G +C
Sbjct: 383 DSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDD 442
Query: 1021 DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ 1080
+V++C S PC +GGTC+DG + CTCP GYTG NC V C+ +PC NG C + +
Sbjct: 443 NVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHR 502
Query: 1081 YRCECPSGWTGLYC 1094
Y CEC G+ G C
Sbjct: 503 YVCECARGYGGPNC 516
Score = 273 bits (699), Expect = 1e-72
Identities = 132/326 (40%), Positives = 172/326 (52%), Gaps = 23/326 (7%)
Query: 741 CDPGWSGTNCD----INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA 796
C+PGW G C + + + C G CK CR G+ G C +EC
Sbjct: 212 CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECK---------CRVGWQGRYC----DECI 258
Query: 797 SNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNGGECRQSEDYESFSC 855
P GTC ++CNC + G C L C PC+NG C + S++C
Sbjct: 259 RYPGCLHGTCQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQ-GSYTC 314
Query: 856 VCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP 915
C G+ G TCE+ I+EC SPC++G SC + Y C C G+ G+ CE C P
Sbjct: 315 SCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGP 374
Query: 916 CHNGGSCTDGINTAF-CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAG 974
C NGG C+D + + C C G+ G CE+ I+ C+S PC NGA C D D+Y C C AG
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAG 434
Query: 975 FSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGG 1034
FSG HC++N DC S C NGGTC DG+N F+C CPPG+TG C V+ C+ PC +G
Sbjct: 435 FSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGA 494
Query: 1035 TCQDGCGSYRCTCPQGYTGPNCQNLV 1060
TC + Y C C +GY GPNCQ L+
Sbjct: 495 TCHERGHRYVCECARGYGGPNCQFLL 520
Score = 272 bits (696), Expect = 3e-72
Identities = 146/361 (40%), Positives = 192/361 (53%), Gaps = 32/361 (8%)
Query: 416 CSLGANPCEHAGKCINTLGSFECQ------CLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
CS+ P + A G F C C G+ GP C + C+ + C D
Sbjct: 188 CSVFCRPRDDA------FGHFTCGERGEKVCNPGWKGPYCTEPI--CLPGCDEQHGFC-D 238
Query: 470 QIGEFQCICMPGYEGVHCEVNTDECASSP-CLHNGRCLDKINEFQCECPTGFTGHLCQYD 528
+ GE C C G++G +C DEC P CLH G C +QC C G+ G C D
Sbjct: 239 KPGE--CKCRVGWQGRYC----DECIRYPGCLH-GTCQQP---WQCNCQEGWGGLFCNQD 288
Query: 529 VDECAS-TPCKNGAKCLD-GPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVA 585
++ C PCKNGA C + G +YTC C GYTG CE+ IDECDP PC + GSC D
Sbjct: 289 LNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLEN 348
Query: 586 TFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDR-DNAYLCFCLKGTTGPNCEINLDD 644
+++C C PG+ G CE + C+ PC +GG C D D Y C C G +G NCE +D
Sbjct: 349 SYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDY 408
Query: 645 CASSPCDSGT-CLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR 703
C+SSPC +G C+D D Y C C+ G++G C+ N+D+CA +PC NGGTC DG+N F+C
Sbjct: 409 CSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCT 468
Query: 704 CPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPC 762
CP GY C + V+ C PC +GA C + + Y C+C G+ G NC E P
Sbjct: 469 CPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPA 528
Query: 763 V 763
V
Sbjct: 529 V 529
Score = 266 bits (679), Expect = 3e-70
Identities = 126/327 (38%), Positives = 170/327 (51%), Gaps = 16/327 (4%)
Query: 663 ECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNS 722
E C PG+ G C I C G C+ C+C G+ C +EC
Sbjct: 209 EKVCNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIR 259
Query: 723 NP-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN-PCVNGGTCKDMTSG-YVCTC 779
P C+HG C+ ++C+C GW G C+ + N C + PC NG TC + G Y C+C
Sbjct: 260 YPGCLHGTCQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316
Query: 780 REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
R G++G C+ I+EC +PC N G+C D Y C C + G CE+ CA PC
Sbjct: 317 RPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCF 376
Query: 840 NGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGY 899
NGG C S D +SC CP G+ G CE I+ C SPC +GA C + Y C CQAG+
Sbjct: 377 NGGRCSDSPD-GGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGF 435
Query: 900 SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGAN 959
SGR+C+ ++DDC +PC NGG+C DG+N C C PG+ G C ++ C PC NGA
Sbjct: 436 SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGAT 495
Query: 960 CTDCVDSYTCTCPAGFSGIHCENNTPD 986
C + Y C C G+ G +C+ P+
Sbjct: 496 CHERGHRYVCECARGYGGPNCQFLLPE 522
Score = 263 bits (672), Expect = 2e-69
Identities = 139/379 (36%), Positives = 188/379 (49%), Gaps = 33/379 (8%)
Query: 662 YECACEPGYTGSMCNINI---DECAGN-PCHNGG--TCEDGINGFTCRCPEGYHDPTCLS 715
Y C+ Y G C++ D+ G+ C G C G G C +P CL
Sbjct: 175 YRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCT------EPICLP 228
Query: 716 EVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGY 775
+E HG C +C C GW G CD EC P GTC+ +
Sbjct: 229 GCDE------QHGFCDKP---GECKCRVGWQGRYCD----ECIRYPGCLHGTCQQP---W 272
Query: 776 VCTCREGFSGPNCQTNINECASN-PCLNQGTCIDDVAG-YKCNCLLPYTGATCEVVLAPC 833
C C+EG+ G C ++N C + PC N TC + G Y C+C YTGATCE+ + C
Sbjct: 273 QCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDEC 332
Query: 834 APSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNT-HGGYR 892
PSPC+NGG C E+ S+SC CP G+ G+ CE+ C PC +G C ++ GGY
Sbjct: 333 DPSPCKNGGSCTDLEN--SYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYS 390
Query: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
C C GYSG NCE ID C +PC NG C D + C C GF G C++++++CAS
Sbjct: 391 CRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASS 450
Query: 953 PCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1012
PC NG C D V+ ++CTCP G++G +C C + C NG TC + + + C C G
Sbjct: 451 PCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARG 510
Query: 1013 FTGSYCQHDVNECDSQPCL 1031
+ G CQ + E P +
Sbjct: 511 YGGPNCQFLLPELPPGPAV 529
Score = 254 bits (650), Expect = 6e-67
Identities = 138/401 (34%), Positives = 189/401 (47%), Gaps = 44/401 (10%)
Query: 852 SFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH------CQAGYSGRNCE 905
S+ VC + G+ C V CR + G + C C G+ G C
Sbjct: 174 SYRFVCDEHYYGEGCSVF--------CRPR---DDAFGHFTCGERGEKVCNPGWKGPYCT 222
Query: 906 TDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDP-CRNGANCTDCV 964
I C P G C C C G++G +C+E C P C +G C
Sbjct: 223 EPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYCDE----CIRYPGCLHGT----CQ 269
Query: 965 DSYTCTCPAGFSGIHCENNTPDCTESS-CFNGGTCVD-GINSFTCLCPPGFTGSYCQHDV 1022
+ C C G+ G+ C + CT C NG TC + G S+TC C PG+TG+ C+ +
Sbjct: 270 QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGI 329
Query: 1023 NECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ-Y 1081
+ECD PC +GG+C D SY CTCP G+ G C+ C PC NGG+C + Y
Sbjct: 330 DECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGY 389
Query: 1082 RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSY 1141
C CP G++G C+ C + C +G CVD G+ + CRCQAG++G +
Sbjct: 390 SCRCPVGYSGFNCEKKIDYCSSSP----------CSNGAKCVDLGDAYLCRCQAGFSGRH 439
Query: 1142 CEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDL 1201
C+D VD+C+ SPC NG TC D + +SC C GY G NCS + C PC NG TC +
Sbjct: 440 CDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHER 499
Query: 1202 PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNG 1242
+ Y C C RG G +C+ + + P V + K G
Sbjct: 500 GHRYVCECARGYGGPNCQFLLPELPPGPAVVDLTEKLEGQG 540
Score = 247 bits (630), Expect = 1e-64
Identities = 138/379 (36%), Positives = 183/379 (48%), Gaps = 30/379 (7%)
Query: 201 SYRCVCRATHTGPNCERPYVPCSPSPCQNGG-TCRPTGDVTHECACLPGFTGQNCEENID 259
SYR VC + G C V C P G TC G E C PG+ G C E I
Sbjct: 174 SYRFVCDEHYYGEGCS---VFCRPRDDAFGHFTCGERG----EKVCNPGWKGPYCTEPIC 226
Query: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGY 319
PG + ++G G C+C W G+YC DEC P GTC +
Sbjct: 227 -LPGCDEQHGFCDKPG----ECKCRVGWQGRYC----DECIRYPGCLH--GTCQQP---W 272
Query: 320 NCVCVNGWTGEDCSENIDDCAS-AACFHGATCHDR-VASFYCECPHGRTGLLCHLN-DAC 376
C C GW G C+++++ C C +GATC + S+ C C G TG C L D C
Sbjct: 273 QCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDEC 332
Query: 377 ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTL-GS 435
+PC G +C + CTCP G+ G C C+ G PC + G+C ++ G
Sbjct: 333 DPSPCKNGGSC--TDLENSYSCTCPPGFYGKICELSAMTCADG--PCFNGGRCSDSPDGG 388
Query: 436 FECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECA 495
+ C+C GY+G CE ++ C S+PC N A C+D + C C G+ G HC+ N D+CA
Sbjct: 389 YSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCA 448
Query: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT 555
SSPC + G C D +N+F C CP G+TG C V C PC NGA C + + Y C C
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECA 508
Query: 556 EGYTGTHCEVDIDECDPDP 574
GY G +C+ + E P P
Sbjct: 509 RGYGGPNCQFLLPELPPGP 527
Score = 244 bits (624), Expect = 6e-64
Identities = 122/333 (36%), Positives = 160/333 (48%), Gaps = 21/333 (6%)
Query: 283 CPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA 342
C P W G YCTE + +P + G C C C GW G C E I
Sbjct: 212 CNPGWKGPYCTEPI----CLPGCDEQHGFCDKPG---ECKCRVGWQGRYCDECI---RYP 261
Query: 343 ACFHGATCHDRVASFYCECPHGRTGLLCH--LNDACISNPCNEGSNCDTNPVNGKAICTC 400
C HG TC + C C G GL C+ LN PC G+ C TN G C+C
Sbjct: 262 GCLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATC-TNTGQGSYTCSC 316
Query: 401 PSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNP 460
GYTG C +DEC +PC++ G C + S+ C C G+ G CE+ C P
Sbjct: 317 RPGYTGATCELGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGP 374
Query: 461 CQNDATCLDQI-GEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTG 519
C N C D G + C C GY G +CE D C+SSPC + +C+D + + C C G
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAG 434
Query: 520 FTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG- 578
F+G C +VD+CAS+PC NG C DG N ++C C GYTG +C + C+ PCH G
Sbjct: 435 FSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGA 494
Query: 579 SCKDGVATFTCLCRPGYTGHHCETNINECSSQP 611
+C + + C C GY G +C+ + E P
Sbjct: 495 TCHERGHRYVCECARGYGGPNCQFLLPELPPGP 527
Score = 243 bits (620), Expect = 2e-63
Identities = 133/359 (37%), Positives = 172/359 (47%), Gaps = 47/359 (13%)
Query: 962 DCVDSYTC------TCPAGFSGIHCENNTPDCTESSCFNGGTCVDGI--NSFTCLCPPGF 1013
D +TC C G+ G P CTE C G G C C G+
Sbjct: 197 DAFGHFTCGERGEKVCNPGWKG-------PYCTEPICLPGCDEQHGFCDKPGECKCRVGW 249
Query: 1014 TGSYCQHDVNECDSQP-CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDS-SPCKNG 1071
G YC +EC P CLHG TCQ ++C C +G+ G C +++C PCKNG
Sbjct: 250 QGRYC----DECIRYPGCLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 1072 GKCWQT-HTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH 1130
C T Y C C G+TG C++ C+ + C++GG C D N++
Sbjct: 302 ATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSP----------CKNGGSCTDLENSYS 351
Query: 1131 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYL-GGYSCKCVAGYHGVNCSEEIDECLS 1189
C C G+ G CE C+ PC NG C+D GGYSC+C GY G NC ++ID C S
Sbjct: 352 CTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS 411
Query: 1190 HPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVG 1249
PC NG C+DL + Y C C G G HC+ NVDDC S C N GTC D V
Sbjct: 412 SPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDC--------ASSPCANGGTCRDGVN 463
Query: 1250 GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI 1308
+SCTCPPG+ G C V+ C PC T C +R + + CEC G+ G C+ ++
Sbjct: 464 DFSCTCPPGYTGRNCSAPVSRCEHAPCHNGAT--CHERGHRYVCECARGYGGPNCQFLL 520
Score = 233 bits (594), Expect = 2e-60
Identities = 118/326 (36%), Positives = 158/326 (48%), Gaps = 39/326 (11%)
Query: 20 RGPRCSQPGETCLNG-----------GKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPC 68
+GP C++P CL G G+C+ G + C + C+ P
Sbjct: 217 KGPYCTEP--ICLPGCDEQHGFCDKPGECKCRVGWQGRYC------------DECIRYPG 262
Query: 69 KNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCR 128
GTC + C+C G+ G C L+ PC+NG TC Y C
Sbjct: 263 CLHGTCQ-------QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCS 315
Query: 129 CPPGWSGKSCQQA-DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPG 187
C PG++G +C+ D C +PC NGG C E SY C CPP F+G C C P
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGP- 374
Query: 188 LCRHGGTCHNEV-GSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACL 246
C +GG C + G Y C C ++G NCE+ CS SPC NG C GD + C C
Sbjct: 375 -CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGD-AYLCRCQ 432
Query: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
GF+G++C++N+DDC + C NGG C DGVN ++C CPP +TG+ C+ V C+ P C
Sbjct: 433 AGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAP--C 490
Query: 307 QNGGTCHNTHGGYNCVCVNGWTGEDC 332
NG TCH Y C C G+ G +C
Sbjct: 491 HNGATCHERGHRYVCECARGYGGPNC 516
Score = 231 bits (589), Expect = 7e-60
Identities = 119/327 (36%), Positives = 164/327 (50%), Gaps = 24/327 (7%)
Query: 47 VCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNAC 106
VC + GP C +P CL + G C D+ G C C +G+ G C + C
Sbjct: 211 VCNPGWKGPYCTEPI-CLPGCDEQHGFC---DKPG----ECKCRVGWQGRYC-----DEC 257
Query: 107 LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ-ADPCASN-PCANGGQCLPF-EASYI 163
+ P GTC ++C C GW G C Q + C + PC NG C + SY
Sbjct: 258 IRYPGCLHGTCQ----QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYT 313
Query: 164 CHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS 223
C C P + G TC ++EC P C++GG+C + SY C C G CE + C+
Sbjct: 314 CSCRPGYTGATCELGIDECDPSP--CKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCA 371
Query: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRC 283
PC NGG C + D + C C G++G NCE+ ID C + C NG CVD + Y CRC
Sbjct: 372 DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRC 431
Query: 284 PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA 343
++G++C ++VD+C P C NGGTC + ++C C G+TG +CS + C A
Sbjct: 432 QAGFSGRHCDDNVDDCASSP--CANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAP 489
Query: 344 CFHGATCHDRVASFYCECPHGRTGLLC 370
C +GATCH+R + CEC G G C
Sbjct: 490 CHNGATCHERGHRYVCECARGYGGPNC 516
Score = 221 bits (564), Expect = 5e-57
Identities = 126/341 (36%), Positives = 170/341 (49%), Gaps = 22/341 (6%)
Query: 129 CPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGL 188
C PGW G C + C G C + C C + G C +EC + PG
Sbjct: 212 CNPGWKGPYCTEPI-CLPGCDEQHGFC---DKPGECKCRVGWQGRYC----DECIRYPG- 262
Query: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSP-SPCQNGGTCRPTGDVTHECACLP 247
C HG TC ++C C+ G C + C+ PC+NG TC TG ++ C+C P
Sbjct: 263 CLHG-TCQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRP 318
Query: 248 GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
G+TG CE ID+C + CKNGG+C D N+Y+C CPP + G+ C C P C
Sbjct: 319 GYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGP--CF 376
Query: 308 NGGTCHNT-HGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRT 366
NGG C ++ GGY+C C G++G +C + ID C+S+ C +GA C D ++ C C G +
Sbjct: 377 NGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFS 436
Query: 367 GLLCHLN-DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEH 425
G C N D C S+PC G C + VN + CTCP GYTG CS V C PC +
Sbjct: 437 GRHCDDNVDDCASSPCANGGTC-RDGVNDFS-CTCPPGYTGRNCSAPVSRCEHA--PCHN 492
Query: 426 AGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDAT 466
C + C+C +GY GP C+ + E P D T
Sbjct: 493 GATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAVVDLT 533
Score = 214 bits (546), Expect = 7e-55
Identities = 136/406 (33%), Positives = 176/406 (43%), Gaps = 57/406 (14%)
Query: 1031 LHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSS----PCKNGGKCWQTHTQYRCECP 1086
LH D SYR C + Y G C D + C G+ C
Sbjct: 163 LHSSGRTDLKYSYRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEK---------VCN 213
Query: 1087 SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLV 1146
GW G YC P G D QHG C G C+C+ G+ G YC
Sbjct: 214 PGWKGPYCTEPICL-------PGCDE----QHG-FCDKPGE---CKCRVGWQGRYC---- 254
Query: 1147 DECSPSP-CQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSH-PCQNGGTCLDL-PN 1203
DEC P C +G TC + C C G+ G+ C+++++ C H PC+NG TC +
Sbjct: 255 DECIRYPGCLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQG 310
Query: 1204 TYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGER 1263
+Y CSC G G CE+ +D+C+P SP C N G+C D YSCTCPPGF G+
Sbjct: 311 SYTCSCRPGYTGATCELGIDECDP-------SP-CKNGGSCTDLENSYSCTCPPGFYGKI 362
Query: 1264 CEGDVNECLSNPCDARGTQNCVQRVND-FHCECRAGHTGRRCESVINGCKGKPCKNGGTC 1322
CE C PC G C + + C C G++G CE I+ C PC NG C
Sbjct: 363 CELSAMTCADGPCFNGG--RCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC 420
Query: 1323 AVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPE 1382
+ ++C+C AGF G C+++ C S C NGGTC G +C C +TG
Sbjct: 421 V---DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRN 477
Query: 1383 CQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHIL 1428
C P S PC+N TC Y C C + G C L
Sbjct: 478 CSAPVSR--CEHAPCHNGATCHERGHR--YVCECARGYGGPNCQFL 519
Score = 140 bits (354), Expect = 1e-32
Identities = 75/199 (37%), Positives = 95/199 (47%), Gaps = 11/199 (5%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
C NGG C + +C C F G C+ C PC N G C G Y+C C
Sbjct: 337 CKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGG---YSCRC 393
Query: 90 ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ-ADPCASNP 148
+G+SG C +D C ++PC NG C L Y CRC G+SG+ C D CAS+P
Sbjct: 394 PVGYSGFNCEKKIDY-CSSSPCSNGAKCVDLG-DAYLCRCQAGFSGRHCDDNVDDCASSP 451
Query: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
CANGG C + C CPP + G C V+ C P C +G TCH Y C C
Sbjct: 452 CANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAP--CHNGATCHERGHRYVCECAR 509
Query: 209 THTGPNCE--RPYVPCSPS 225
+ GPNC+ P +P P+
Sbjct: 510 GYGGPNCQFLLPELPPGPA 528
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 272 bits (696), Expect = 3e-72
Identities = 124/300 (41%), Positives = 167/300 (55%), Gaps = 11/300 (3%)
Query: 423 CEHAGKCIN--TLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD----QIGE-FQ 475
C GKC + +F C C + Y G CE + + C PCQN+A+C+D Q G F
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 476 CICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAST 535
C+C+PGY G C+ D C PC + C+ ++ F C+CP G+ G C+ VD CAS+
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 536 PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGY 595
PC+N C +TC C+ G+TG C ID C PC +G+C+ ++ CLC PGY
Sbjct: 438 PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGY 497
Query: 596 TGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTC 655
G +CE NEC S PC + TC+D N Y C CL G +CE+ D CA+ C +G
Sbjct: 498 HGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGAT 557
Query: 656 LDKIDGYE--CACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC 713
D DG C C PG+TG C+I+I+EC NPCH+GG+C D NG+ C CP G+ C
Sbjct: 558 CDS-DGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 268 bits (685), Expect = 5e-71
Identities = 127/323 (39%), Positives = 166/323 (51%), Gaps = 13/323 (4%)
Query: 748 TNCDINNNECESNPCVNGGTC--KDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGT 805
+ C + C G C K + + CTC E + G C+ + C PC N +
Sbjct: 305 STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNAS 363
Query: 806 CID-----DVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTG 860
CID D + + C CL YTG C+ + C PCRNG C S F+C CP G
Sbjct: 364 CIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISS--LSGFTCQCPEG 421
Query: 861 WQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 920
+ G CE ++ C SPC++ +C + C+C G++G C ID C +PC +G
Sbjct: 422 YFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG- 480
Query: 921 SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 980
+C + C C PG+ G +CEE+ NEC S PC N A C D V+ Y C C A + G HC
Sbjct: 481 TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHC 540
Query: 981 ENNTPDCTESSCFNGGTC-VDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDG 1039
E C SC NG TC DG+N TC+C PGFTG C D+NECDS PC HGG+C D
Sbjct: 541 ELYKDPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQ 599
Query: 1040 CGSYRCTCPQGYTGPNCQNLVHW 1062
Y C CP G+ G NC+ + W
Sbjct: 600 PNGYNCHCPHGWVGANCEIHLQW 622
Score = 261 bits (667), Expect = 6e-69
Identities = 121/323 (37%), Positives = 166/323 (51%), Gaps = 21/323 (6%)
Query: 565 VDIDECDPDPCHY--------GSC--KDGVATFTCLCRPGYTGHHCETNINECSSQPCRH 614
V + C P H G C K ATF+C C Y G CE + C +PC++
Sbjct: 302 VKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQN 360
Query: 615 GGTCQDRDNA-----YLCFCLKGTTGPNCEINLDDCASSPCDSG-TCLDKIDGYECACEP 668
+C D + + C CL G TG C+ +D C PC +G TC+ + G+ C C
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPE 420
Query: 669 GYTGSMCNINIDECAGNPCHNGGTCE-DGINGFTCRCPEGYHDPTCLSEVNECNSNPCVH 727
GY GS C +D CA +PC N GTC DG++ FTC C G+ PTC ++ C +PC H
Sbjct: 421 GYFGSACEEKVDPCASSPCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDFCALSPCAH 479
Query: 728 GACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPN 787
G CR YKC CDPG+ G C+ NEC S PC+N TC+D+ +GY C C + G +
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTH 539
Query: 788 CQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
C+ + CA+ CLN TC D C C +TG C++ + C +PC +GG C
Sbjct: 540 CELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQ 599
Query: 848 EDYESFSCVCPTGWQGQTCEVDI 870
+ ++C CP GW G CE+ +
Sbjct: 600 PN--GYNCHCPHGWVGANCEIHL 620
Score = 261 bits (666), Expect = 8e-69
Identities = 128/318 (40%), Positives = 161/318 (50%), Gaps = 11/318 (3%)
Query: 329 GEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNC- 387
GE + +++ C T A+F C C G C DAC PC ++C
Sbjct: 310 GESHANDLECSGKGKC----TTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCI 365
Query: 388 DTNPVNGKA--ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT 445
D N + C C GYTG C +D C L +PC + CI++L F CQC +GY
Sbjct: 366 DANEKQDGSNFTCVCLPGYTGELCQSKIDYCIL--DPCRNGATCISSLSGFTCQCPEGYF 423
Query: 446 GPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC 505
G CE V+ C S+PCQN+ TC F C C PG+ G C D CA SPC H G C
Sbjct: 424 GSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAH-GTC 482
Query: 506 LDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV 565
++C C G+ G C+ + +EC S PC N A C D N Y CVC Y GTHCE+
Sbjct: 483 RSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCEL 542
Query: 566 DIDECDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNA 624
D C C G +C TC+C PG+TG C+ +INEC S PC HGG+C D+ N
Sbjct: 543 YKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNG 602
Query: 625 YLCFCLKGTTGPNCEINL 642
Y C C G G NCEI+L
Sbjct: 603 YNCHCPHGWVGANCEIHL 620
Score = 251 bits (640), Expect = 8e-66
Identities = 123/315 (39%), Positives = 166/315 (52%), Gaps = 21/315 (6%)
Query: 916 CHNGGSCTDGINTAF--CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVD-----SYT 968
C G CT + A C C + GTFCEE + C PC+N A+C D + ++T
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 969 CTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQ 1028
C C G++G C++ C C NG TC+ ++ FTC CP G+ GS C+ V+ C S
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 1029 PCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 1088
PC + GTC + C C G+TGP C L+ +C SPC +G C T Y+C C G
Sbjct: 438 PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKCLCDPG 496
Query: 1089 WTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDE 1148
+ GLYC+ C A C + C D N + C C A Y G++CE D
Sbjct: 497 YHGLYCEEEYNECLSAP----------CLNAATCRDLVNGYECVCLAEYKGTHCELYKDP 546
Query: 1149 CSPSPCQNGATC-TDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKC 1207
C+ C NGATC +D L G +C C G+ G C +I+EC S+PC +GG+CLD PN Y C
Sbjct: 547 CANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNC 605
Query: 1208 SCPRGTQGVHCEINV 1222
CP G G +CEI++
Sbjct: 606 HCPHGWVGANCEIHL 620
Score = 251 bits (640), Expect = 8e-66
Identities = 111/303 (36%), Positives = 160/303 (52%), Gaps = 9/303 (2%)
Query: 800 CLNQGTCID--DVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGEC---RQSEDYESFS 854
C +G C A + C C Y G CE A C PC+N C + +D +F+
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDA-CQRKPCQNNASCIDANEKQDGSNFT 377
Query: 855 CVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPN 914
CVC G+ G+ C+ I+ C+L PCR+GA+C ++ G+ C C GY G CE +D C +
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 915 PCHNGGSC-TDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPA 973
PC N G+C DG++ C+C PGF G C + I+ CA PC +G C SY C C
Sbjct: 438 PCQNNGTCYVDGVHFT-CNCSPGFTGPTCAQLIDFCALSPCAHGT-CRSVGTSYKCLCDP 495
Query: 974 GFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHG 1033
G+ G++CE +C + C N TC D +N + C+C + G++C+ + C + CL+G
Sbjct: 496 GYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNG 555
Query: 1034 GTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLY 1093
TC + C C G+TG C ++ CDS+PC +GG C Y C CP GW G
Sbjct: 556 ATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGAN 615
Query: 1094 CDV 1096
C++
Sbjct: 616 CEI 618
Score = 247 bits (630), Expect = 1e-64
Identities = 119/322 (36%), Positives = 167/322 (51%), Gaps = 15/322 (4%)
Query: 371 HLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCI 430
H ND C+ C T P CTC Y G C ++ D C PC++ CI
Sbjct: 313 HANDL----ECSGKGKCTTKPSEATFSCTCEEQYVGTFC-EEYDACQ--RKPCQNNASCI 365
Query: 431 NTL-----GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGV 485
+ +F C CL GYTG C+ ++ C+ +PC+N ATC+ + F C C GY G
Sbjct: 366 DANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGS 425
Query: 486 HCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLD 545
CE D CASSPC +NG C F C C GFTG C +D CA +PC +G C
Sbjct: 426 ACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGT-CRS 484
Query: 546 GPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNI 604
+Y C+C GY G +CE + +EC PC + +C+D V + C+C Y G HCE
Sbjct: 485 VGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYK 544
Query: 605 NECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD-SGTCLDKIDGYE 663
+ C++ C +G TC C C G TG C+I++++C S+PC G+CLD+ +GY
Sbjct: 545 DPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYN 604
Query: 664 CACEPGYTGSMCNINIDECAGN 685
C C G+ G+ C I++ +G+
Sbjct: 605 CHCPHGWVGANCEIHLQWKSGH 626
Score = 243 bits (619), Expect = 2e-63
Identities = 120/317 (37%), Positives = 176/317 (55%), Gaps = 20/317 (6%)
Query: 27 PGET------CLNGGKC--EAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTC-HVV 77
PGE+ C GKC + + T +C C +VG C++ + C PC+N +C
Sbjct: 309 PGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDAN 368
Query: 78 DRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKS 137
+++ +++ C C G++G LC + +D C+ +PCRNG TC + +L+ + C+CP G+ G +
Sbjct: 369 EKQDGSNFTCVCLPGYTGELCQSKID-YCILDPCRNGATC-ISSLSGFTCQCPEGYFGSA 426
Query: 138 CQQ-ADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCH 196
C++ DPCAS+PC N G C + C+C P F GPTC Q ++ C P C H GTC
Sbjct: 427 CEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSP--CAH-GTCR 483
Query: 197 NEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEE 256
+ SY+C+C + G CE Y C +PC N TCR + +EC CL + G +CE
Sbjct: 484 SVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVN-GYECVCLAEYKGTHCEL 542
Query: 257 NIDDCPGNNCKNGGAC-VDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT 315
D C +C NG C DG+N C C P +TG+ C D++EC N C +GG+C +
Sbjct: 543 YKDPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECD--SNPCHHGGSCLDQ 599
Query: 316 HGGYNCVCVNGWTGEDC 332
GYNC C +GW G +C
Sbjct: 600 PNGYNCHCPHGWVGANC 616
Score = 214 bits (546), Expect = 7e-55
Identities = 105/311 (33%), Positives = 157/311 (50%), Gaps = 15/311 (4%)
Query: 68 CKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTC----DLLTLT 123
C G C + A ++C+C + G C +AC PC+N +C + +
Sbjct: 319 CSGKGKC--TTKPSEATFSCTCEEQYVGTFCEEY--DACQRKPCQNNASCIDANEKQDGS 374
Query: 124 EYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNEC 182
+ C C PG++G+ CQ + D C +PC NG C+ + + C CP + G C + V+ C
Sbjct: 375 NFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPC 434
Query: 183 GQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHE 242
P C++ GTC+ + + C C TGP C + C+ SPC +G TCR G +++
Sbjct: 435 ASSP--CQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVG-TSYK 490
Query: 243 CACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLM 302
C C PG+ G CEE ++C C N C D VN Y C C E+ G +C D C +
Sbjct: 491 CLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANV 550
Query: 303 PNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECP 362
+C NG TC + C+C G+TGE+C +I++C S C HG +C D+ + C CP
Sbjct: 551 --SCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCP 608
Query: 363 HGRTGLLCHLN 373
HG G C ++
Sbjct: 609 HGWVGANCEIH 619
Score = 207 bits (527), Expect = 1e-52
Identities = 112/324 (34%), Positives = 148/324 (45%), Gaps = 32/324 (9%)
Query: 1068 CKNGGKCWQTHTQ--YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1125
C GKC ++ + C C + G +C+ A QR+ CQ+ C+DA
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYD-----ACQRKP------CQNNASCIDA 367
Query: 1126 -----GNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNC 1180
G+ C C GYTG C+ +D C PC+NGATC L G++C+C GY G C
Sbjct: 368 NEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSAC 427
Query: 1181 SEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFN 1240
E++D C S PCQN GTC + C+C G G C +D C + P +
Sbjct: 428 EEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFC--ALSPCA------- 478
Query: 1241 NGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT 1300
+GTC Y C C PG+ G CE + NECLS PC T C VN + C C A +
Sbjct: 479 HGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAAT--CRDLVNGYECVCLAEYK 536
Query: 1301 GRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNG 1360
G CE + C C NG TC + C C GF G C+ D C S C +G
Sbjct: 537 GTHCELYKDPCANVSCLNGATC---DSDGLNGTCICAPGFTGEECDIDINECDSNPCHHG 593
Query: 1361 GTCISGPRSPTCLCLGPFTGPECQ 1384
G+C+ P C C + G C+
Sbjct: 594 GSCLDQPNGYNCHCPHGWVGANCE 617
Score = 88.2 bits (217), Expect = 9e-17
Identities = 91/352 (25%), Positives = 124/352 (35%), Gaps = 90/352 (25%)
Query: 1254 TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVND--FHCECRAGHTGRRCESVINGC 1311
TC PG E +N + G C + ++ F C C + G CE + C
Sbjct: 306 TCVPG-----------ESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY-DAC 353
Query: 1312 KGKPCKNGGTCAVASNTARG--FICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRS 1369
+ KPC+N +C A+ G F C C G+ G C++ C C NG TCIS
Sbjct: 354 QRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSG 413
Query: 1370 PTCLCLGPFTGPECQFP----ASSPCLGGNPCYNQG-----TCEPTSESP---------- 1410
TC C + G C+ ASSPC CY G C P P
Sbjct: 414 FTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCA 473
Query: 1411 --------------FYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQE 1456
Y+CLC ++GL C +Y+ C C
Sbjct: 474 LSPCAHGTCRSVGTSYKCLCDPGYHGLYCE-EEYN----------------ECLSAPCLN 516
Query: 1457 DAGNKVCSLQCNNHAC----GWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSA 1512
A C N + C + G C L + DP N + C + CDS +
Sbjct: 517 AA---TCRDLVNGYECVCLAEYKGTHCEL-YKDPCAN----VSC---LNGATCDSDGLNG 565
Query: 1513 GCL----FDGFDCQRAEGQC--NPL-YDQYCKDHFS--DGHCDQGCNSAECE 1555
C+ F G +C +C NP + C D + + HC G A CE
Sbjct: 566 TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 73.9 bits (180), Expect = 2e-12
Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 13/87 (14%)
Query: 832 PCAPSPCRNGGECRQSEDYE----------SFSCVCPTGWQGQTCEVDINECVLSPCRHG 881
PCA PCRNGG C + + +SC CP G G C++ + C +PC HG
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 882 ---ASCQNTHGGYRCHCQAGYSGRNCE 905
+S ++ GY C C GY G NCE
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 70.9 bits (172), Expect = 2e-11
Identities = 33/85 (38%), Positives = 41/85 (48%), Gaps = 16/85 (18%)
Query: 607 CSSQPCRHGGTCQDR------------DNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT 654
C++QPCR+GG C R + Y C C G +G NC++ D CAS+PC G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 655 C----LDKIDGYECACEPGYTGSMC 675
C DGY C C GY G C
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 69.7 bits (169), Expect = 3e-11
Identities = 41/111 (36%), Positives = 49/111 (44%), Gaps = 28/111 (25%)
Query: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDC 741
CA PC NGG C T R PE DP + E GY C C
Sbjct: 48 CAAQPCRNGGVC-------TSR-PEP--DPQHPAPAGE---------------PGYSCTC 82
Query: 742 DPGWSGTNCDINNNECESNPCVNGGTCKDMTS---GYVCTCREGFSGPNCQ 789
G SG NC + + C SNPC +G +S GY+C C EG+ GPNC+
Sbjct: 83 PAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 68.6 bits (166), Expect = 8e-11
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 16/86 (18%)
Query: 532 CASTPCKNGAKCLDGPNT------------YTCVCTEGYTGTHCEVDIDECDPDPCHYGS 579
CA+ PC+NG C P Y+C C G +G +C++ D C +PCH+G+
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 580 CKDGVAT----FTCLCRPGYTGHHCE 601
C ++ + C+C GY G +CE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 68.2 bits (165), Expect = 1e-10
Identities = 39/102 (38%), Positives = 47/102 (46%), Gaps = 19/102 (18%)
Query: 94 SGPLCLTPLD--NACLTNPCRNGGTCDLLTLTE-----------YKCRCPPGWSGKSCQ- 139
+ P+ PL C PCRNGG C + Y C CP G SG +CQ
Sbjct: 34 ANPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL 93
Query: 140 QADPCASNPCANGGQCLPFEAS----YICHCPPSFHGPTCRQ 177
ADPCASNPC + G C +S Y+C C + GP C Q
Sbjct: 94 VADPCASNPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 64.3 bits (155), Expect = 1e-09
Identities = 37/96 (38%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 757 CESNPCVNGGTCKDMTS------------GYVCTCREGFSGPNCQTNINECASNPCLNQG 804
C + PC NGG C GY CTC G SG NCQ + CASNPC + G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC-HHG 106
Query: 805 TCIDDVA----GYKCNCLLPYTGATCEVVLAPCAPS 836
C + GY C C Y G CE L P P+
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQAL-PSLPA 141
Score = 63.9 bits (154), Expect = 2e-09
Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 987 CTESSCFNGGTCVD------------GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGG 1034
C C NGG C G ++C CP G +G+ CQ + C S PC HG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 1035 TCQDGCGS---YRCTCPQGYTGPNCQ 1057
S Y C C +GY GPNC+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 62.4 bits (150), Expect = 6e-09
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 15/86 (17%)
Query: 494 CASSPCLHNGRCLDKINE------------FQCECPTGFTGHLCQYDVDECASTPCKNG- 540
CA+ PC + G C + + C CP G +G CQ D CAS PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 541 --AKCLDGPNTYTCVCTEGYTGTHCE 564
+ + Y C+C EGY G +CE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 61.6 bits (148), Expect = 9e-09
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 13/86 (15%)
Query: 795 CASNPCLNQGTCID------------DVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGG 842
CA+ PC N G C GY C C +GA C++V PCA +PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 843 -ECRQSEDYESFSCVCPTGWQGQTCE 867
S + + C+C G++G CE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 60.1 bits (144), Expect = 3e-08
Identities = 32/98 (32%), Positives = 41/98 (41%), Gaps = 19/98 (19%)
Query: 143 PCASNPCANGGQCLPF------------EASYICHCPPSFHGPTCRQDVNECGQKPGLCR 190
PCA+ PC NGG C E Y C CP G C+ + C P C
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNP--CH 104
Query: 191 HGGTCHNEVGS---YRCVCRATHTGPNCER--PYVPCS 223
HG + S Y C+C + GPNCE+ P +P +
Sbjct: 105 HGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPAT 142
Score = 59.7 bits (143), Expect = 4e-08
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 15/86 (17%)
Query: 949 CASDPCRNGANCTDCVD------------SYTCTCPAGFSGIHCENNTPDCTESSCFNGG 996
CA+ PCRNG CT + Y+CTCPAG SG +C+ C + C +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 997 TCVDGINS---FTCLCPPGFTGSYCQ 1019
+S + C+C G+ G C+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 59.7 bits (143), Expect = 4e-08
Identities = 30/86 (34%), Positives = 38/86 (44%), Gaps = 15/86 (17%)
Query: 1149 CSPSPCQNGATCTDYLG------------GYSCKCVAGYHGVNCSEEIDECLSHPCQNGG 1196
C+ PC+NG CT GYSC C AG G NC D C S+PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 1197 TCLDLPNT---YKCSCPRGTQGVHCE 1219
++ Y C C G +G +CE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 58.9 bits (141), Expect = 6e-08
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 13/95 (13%)
Query: 60 PNPCLSTPCKNAGTC---------HVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNP 110
P PC + PC+N G C H G Y+C+C G SG C D C +NP
Sbjct: 45 PGPCAAQPCRNGGVCTSRPEPDPQHPAP-AGEPGYSCTCPAGISGANCQLVAD-PCASNP 102
Query: 111 CRNGGTCDLLTLTE--YKCRCPPGWSGKSCQQADP 143
C +G + + Y C C G+ G +C+QA P
Sbjct: 103 CHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALP 137
Score = 56.6 bits (135), Expect = 3e-07
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 17/87 (19%)
Query: 1025 CDSQPCLHGGTCQD------------GCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1072
C +QPC +GG C G Y CTCP G +G NCQ + C S+PC + G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH-G 106
Query: 1073 KCWQTHTQ----YRCECPSGWTGLYCD 1095
C + + Y C C G+ G C+
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 56.2 bits (134), Expect = 4e-07
Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 17/91 (18%)
Query: 911 CRPNPCHNGGSCTD------------GINTAFCDCLPGFRGTFCEEDINECASDPCRNGA 958
C PC NGG CT G C C G G C+ + CAS+PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG- 106
Query: 959 NC----TDCVDSYTCTCPAGFSGIHCENNTP 985
NC + D Y C C G+ G +CE P
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQALP 137
Score = 56.2 bits (134), Expect = 4e-07
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 17/89 (19%)
Query: 376 CISNPCNEGSNCDTNPVNGKA----------ICTCPSGYTGPACSQDVDECSLGANPCEH 425
C + PC G C + P CTCP+G +G C D C+ +NPC H
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCA--SNPCHH 105
Query: 426 AGKCINTLGS----FECQCLQGYTGPRCE 450
G C ++ S + C C +GY GP CE
Sbjct: 106 -GNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 55.5 bits (132), Expect = 7e-07
Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 14/87 (16%)
Query: 1311 CKGKPCKNGGTCAV---------ASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGG 1361
C +PC+NGG C A G+ C CPAG GA C+ A C S C + G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC-HHG 106
Query: 1362 TCISGPRSPT----CLCLGPFTGPECQ 1384
C S S + C+C + GP C+
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 54.7 bits (130), Expect = 1e-06
Identities = 20/56 (35%), Positives = 33/56 (58%)
Query: 1291 FHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
+ C C AG +G C+ V + C PC +G + +S+++ G++C C G+EG CE
Sbjct: 78 YSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 54.3 bits (129), Expect = 2e-06
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 15/91 (16%)
Query: 1109 GVDVARLCQHGGLCVD-----------AGNT-HHCRCQAGYTGSYCEDLVDECSPSPCQN 1156
G A+ C++GG+C AG + C C AG +G+ C+ + D C+ +PC +
Sbjct: 46 GPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 1157 G---ATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
G ++ + GY C C GY G NC + +
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 54.3 bits (129), Expect = 2e-06
Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 14/88 (15%)
Query: 221 PCSPSPCQNGGTCR-----------PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNG 269
PC+ PC+NGG C P G+ + C C G +G NC+ D C N C +G
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 270 GACVDGVNT---YNCRCPPEWTGQYCTE 294
++ Y C C + G C +
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 25/95 (26%)
Query: 1187 CLSHPCQNGGTCLDLPNT------------YKCSCPRGTQGVHCEINVDDCNPPVDPVSR 1234
C + PC+NGG C P Y C+CP G G +C++ D C
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPC--------A 99
Query: 1235 SPKCFNNGTCVDQVG----GYSCTCPPGFVGERCE 1265
S C ++G C GY C C G+ G CE
Sbjct: 100 SNPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 53.5 bits (127), Expect = 3e-06
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 16/88 (18%)
Query: 339 CASAACFHGATCHDRVA------------SFYCECPHGRTGLLCHL-NDACISNPCNEGS 385
CA+ C +G C R + C CP G +G C L D C SNPC+ G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG- 106
Query: 386 NCDTNPVNGKA--ICTCPSGYTGPACSQ 411
NC ++ + +C C GY GP C Q
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 48.9 bits (115), Expect = 6e-05
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 15/84 (17%)
Query: 420 ANPCEHAGKCINTLG------------SFECQCLQGYTGPRCEIDVNECVSNPCQN---D 464
A PC + G C + + C C G +G C++ + C SNPC +
Sbjct: 50 AQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCS 109
Query: 465 ATCLDQIGEFQCICMPGYEGVHCE 488
++ + CIC GYEG +CE
Sbjct: 110 SSSSSSSDGYLCICNEGYEGPNCE 133
Score = 48.9 bits (115), Expect = 6e-05
Identities = 63/265 (23%), Positives = 85/265 (32%), Gaps = 52/265 (19%)
Query: 1343 ATCENDARTCGSLRCLNGGTCISGPRSPT--CLCLGPFTGPECQFPASSPCLGGNPCYNQ 1400
+TC L C G C + P T C C + G C+ PC N
Sbjct: 305 STCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE---EYDACQRKPCQNN 361
Query: 1401 GTCEPTSE---SPFYRCLCPAKFNGLLCHI-LDYSFGGGA--GRDIPPPLIEEACELPE- 1453
+C +E + C+C + G LC +DY G L C+ PE
Sbjct: 362 ASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEG 421
Query: 1454 -----CQEDAGNKVCSLQCNNHACGWDG----GDCSLNFNDPWKNCTQSLQ--CWKYFSD 1502
C+E S NN C DG +CS F P C Q + +
Sbjct: 422 YFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGP--TCAQLIDFCALSPCAH 479
Query: 1503 GHCDSQCNSAGCLFD----GFDCQRAEGQCNPL--------------YDQYCKDHFSDGH 1544
G C S S CL D G C+ +C Y+ C + H
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTH 539
Query: 1545 CD---------QGCNSAECEWDGLD 1560
C+ N A C+ DGL+
Sbjct: 540 CELYKDPCANVSCLNGATCDSDGLN 564
Score = 43.9 bits (102), Expect = 0.002
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 19/88 (21%)
Query: 299 CQLMPNACQNGGTCHNT------------HGGYNCVCVNGWTGEDCSENIDDCASAACFH 346
C P C+NGG C + GY+C C G +G +C D CAS C H
Sbjct: 48 CAAQP--CRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 347 GATCHDRVAS----FYCECPHGRTGLLC 370
G C +S + C C G G C
Sbjct: 106 G-NCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 43.5 bits (101), Expect = 0.003
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 25/96 (26%)
Query: 1063 CDSSPCKNGGKCWQT------------HTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGV 1110
C + PC+NGG C Y C CP+G +G C + + C
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPC--------- 98
Query: 1111 DVARLCQHGGLCVDAGNT---HHCRCQAGYTGSYCE 1143
+ C HG + ++ + C C GY G CE
Sbjct: 99 -ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 34.7 bits (78), Expect = 1.2
Identities = 25/109 (22%), Positives = 34/109 (31%), Gaps = 24/109 (22%)
Query: 1381 PECQFPASSPCLGGNPCYNQGTCEPTSE----------SPFYRCLCPAKFNGLLCHILDY 1430
P A PC PC N G C E P Y C CPA +G C +
Sbjct: 38 PAAPLSAPGPC-AAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL--- 93
Query: 1431 SFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDC 1479
+ P C C + + C + G++G +C
Sbjct: 94 ---------VADPCASNPCHHGNCSSSSSSSSDGYLCICNE-GYEGPNC 132
Score = 33.9 bits (76), Expect = 2.1
Identities = 52/215 (24%), Positives = 71/215 (33%), Gaps = 55/215 (25%)
Query: 1397 CYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQE 1456
C +G C + C C ++ G C D AC+ CQ
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYD------------------ACQRKPCQN 360
Query: 1457 DAG--NKVCSLQCNNHAC----GWDGGDCSLNFN----DPWKN---CTQSL-----QCWK 1498
+A + +N C G+ G C + DP +N C SL QC +
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPE 420
Query: 1499 YFSDGHCD--------SQC-NSAGCLFDG--FDCQRAEG----QCNPLYDQYCKDHFSDG 1543
+ C+ S C N+ C DG F C + G C L D + G
Sbjct: 421 GYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG 480
Query: 1544 HCDQGCNSAECEWD----GLDCAEHVPERLAAGTL 1574
C S +C D GL C E E L+A L
Sbjct: 481 TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCL 515
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 272 bits (695), Expect = 4e-72
Identities = 149/408 (36%), Positives = 216/408 (52%), Gaps = 52/408 (12%)
Query: 310 GTCHNTHGGYNC-VCVNG-WTGEDCSENIDDCASAACFHGATCHDRVASFYCE-CPHG-- 364
G+ + G C +C +G +T S NI DC A C G + + + CE CP G
Sbjct: 1021 GSYQDEEGQLECKLCPSGMYTEYIHSRNISDC-KAQCKQGTYSYSGLET--CESCPLGTY 1077
Query: 365 ------RTGLLCHLNDACISN----------PCNEGSNCDTN-------------PVNGK 395
R+ L C N + + PC EG + P GK
Sbjct: 1078 QPKFGSRSCLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGK 1137
Query: 396 AIC-TCPSGYTGP-ACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEID- 452
A C CP T P A S+ + ECS ++ A + + S G+ R EI
Sbjct: 1138 AFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASL------GHIKKRHEISS 1191
Query: 453 --VNECVSNPCQNDATCLDQIGE-FQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKI 509
+EC NPC N TC Q+G + C+C GY G+ CE + DEC+ PCL+NG C D +
Sbjct: 1192 QVFHECFFNPCHNSGTC-QQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLV 1250
Query: 510 NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
EF CECP+G+TG C+ +++EC+S+PC N C+DG Y C C +G+ G HCE +++E
Sbjct: 1251 GEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNE 1310
Query: 570 CDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCF 628
C +PC + C+D V F C C PG+ G C N++EC SQPC++G TC+D N++ C
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCL 1370
Query: 629 CLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMC 675
C G TG +CE+N+++C S+PC + TC+D+++ Y C C+PG++G C
Sbjct: 1371 CAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 254 bits (648), Expect = 1e-66
Identities = 104/228 (45%), Positives = 147/228 (64%), Gaps = 5/228 (2%)
Query: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435
C NPC+ C + +C CP GYTG C D+DECS PC + G C + +G
Sbjct: 1197 CFFNPCHNSGTCQQ--LGRGYVCLCPLGYTGLKCETDIDECS--PLPCLNNGVCKDLVGE 1252
Query: 436 FECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECA 495
F C+C GYTG RCE ++NEC S+PC N C+D + ++C C+ G+ G+HCE +EC
Sbjct: 1253 FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1312
Query: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT 555
S+PCL+N C D++ F C+CP GF G C +VDEC S PCKNGA C DG N++ C+C
Sbjct: 1313 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1372
Query: 556 EGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCET 602
G+TG+HCE++I+EC +PC + +C D + +++C C+PG++G CET
Sbjct: 1373 AGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCET 1420
Score = 252 bits (643), Expect = 4e-66
Identities = 151/475 (31%), Positives = 210/475 (44%), Gaps = 58/475 (12%)
Query: 630 LKGTTGPNCEI----NLDDCASSPCDSGTCLDKIDGYECACEPG--YTGSMCNINIDECA 683
L+G NC + NL+ C G+ D+ EC P YT + + NI +C
Sbjct: 994 LRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCK 1053
Query: 684 GNPCHNGGTCEDGINGFTCR-CPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCD 742
C G G+ TC CP G + P + S C+ +C ++ + K
Sbjct: 1054 AQ-CKQGTYSYSGLE--TCESCPLGTYQP-------KFGSRSCL--SCPENTSTVKRGA- 1100
Query: 743 PGWSGTNCDINNNECESNPCVNGGTCKDMTSGYV-C-TCREGFSGPNCQTNINECASNPC 800
+N + C PC G K SG + C C + PN C + P
Sbjct: 1101 ---------VNISAC-GVPCPEG---KFSRSGLMPCHPCPRDYYQPNAGKAF--CLACPF 1145
Query: 801 LNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTG 860
+ +C+ A E V+ P + + E
Sbjct: 1146 YGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQV------------ 1193
Query: 861 WQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 920
+EC +PC + +CQ GY C C GY+G CETDID+C P PC N G
Sbjct: 1194 ---------FHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNG 1244
Query: 921 SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 980
C D + C+C G+ G CEE+INEC+S PC N C D V Y CTC GF G+HC
Sbjct: 1245 VCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHC 1304
Query: 981 ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGC 1040
E +C + C N C D + F C CPPGF G+ C +V+EC SQPC +G TC+DG
Sbjct: 1305 ETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGA 1364
Query: 1041 GSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD 1095
S+RC C G+TG +C+ ++ C S+PC+N C Y C+C G++G C+
Sbjct: 1365 NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 247 bits (631), Expect = 9e-65
Identities = 141/454 (31%), Positives = 208/454 (45%), Gaps = 91/454 (20%)
Query: 553 VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTC-LCRPG-YTGHHCETNINECSSQ 610
+C GT+ ++ C+ C GS +D C LC G YT + NI++C +Q
Sbjct: 998 MCVNCPLGTYYNLEHFTCES--CRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQ 1055
Query: 611 PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGY 670
C +GT + L+ C S C GT K C P
Sbjct: 1056 ------------------CKQGTYSYS---GLETCES--CPLGTYQPKFGSRSCLSCPEN 1092
Query: 671 TGSMCN--INIDECAGNPCHNGGTCEDGINGFTCR-CPEGYHDPT-----CLS------- 715
T ++ +NI C G PC G G+ C CP Y+ P CL+
Sbjct: 1093 TSTVKRGAVNISAC-GVPCPEGKFSRSGL--MPCHPCPRDYYQPNAGKAFCLACPFYGTT 1149
Query: 716 ------EVNECNS-------------------------------------NPCVH-GACR 731
+ EC+S NPC + G C+
Sbjct: 1150 PFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQ 1209
Query: 732 DSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTN 791
GY C C G++G C+ + +EC PC+N G CKD+ ++C C G++G C+ N
Sbjct: 1210 QLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEEN 1269
Query: 792 INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYE 851
INEC+S+PCLN+G C+D VAGY+C C+ + G CE + C +PC N C +
Sbjct: 1270 INECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVC--EDQVG 1327
Query: 852 SFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDC 911
F C CP G+ G C +++EC+ PC++GA+C++ +RC C AG++G +CE +I++C
Sbjct: 1328 GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINEC 1387
Query: 912 RPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEED 945
+ NPC N +C D +N+ C C PGF G CE +
Sbjct: 1388 QSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 246 bits (627), Expect = 3e-64
Identities = 108/224 (48%), Positives = 131/224 (58%), Gaps = 3/224 (1%)
Query: 531 ECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTC 589
EC PC N C Y C+C GYTG CE DIDEC P PC + G CKD V F C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 590 LCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSP 649
C GYTG CE NINECSS PC + G C D Y C C+KG G +CE +++C S+P
Sbjct: 1256 ECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP 1315
Query: 650 C-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGY 708
C ++ C D++ G+ C C PG+ G+ C N+DEC PC NG TC+DG N F C C G+
Sbjct: 1316 CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF 1375
Query: 709 HDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCD 751
C +NEC SNPC + A C D LN Y C C PG+SG C+
Sbjct: 1376 TGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 235 bits (600), Expect = 4e-61
Identities = 152/461 (32%), Positives = 206/461 (44%), Gaps = 68/461 (14%)
Query: 844 CRQSEDYESFSCV-CPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH-CQAG-YS 900
CR CV CP G ++ CR G S Q+ G C C +G Y+
Sbjct: 988 CRPGSVLRGRMCVNCPLGTY-----YNLEHFTCESCRIG-SYQDEEGQLECKLCPSGMYT 1041
Query: 901 GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEE-DINECASDPCRNGAN 959
+I DC+ C G G+ T C+ P GT+ + C S P
Sbjct: 1042 EYIHSRNISDCKAQ-CKQGTYSYSGLET--CESCP--LGTYQPKFGSRSCLSCPENTSTV 1096
Query: 960 CTDCVDSYTC--TCPAGF---SGIH----CENN--TPDCTESSC----FNGGTCVDGINS 1004
V+ C CP G SG+ C + P+ ++ C F G T G S
Sbjct: 1097 KRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRS 1156
Query: 1005 FT--------------CLCPPGFTGSYCQ-HDVN-----ECDSQPCLHGGTCQDGCGSYR 1044
T + PP G + H+++ EC PC + GTCQ Y
Sbjct: 1157 ITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYV 1216
Query: 1045 CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 1104
C CP GYTG C+ + C PC N G C ++ CECPSG+TG C+ C +
Sbjct: 1217 CLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSS 1276
Query: 1105 AQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYL 1164
C + G+CVD + C C G+ G +CE V+EC +PC N A C D +
Sbjct: 1277 P----------CLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQV 1326
Query: 1165 GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1224
GG+ CKC G+ G C + +DECLS PC+NG TC D N+++C C G G HCE+N+++
Sbjct: 1327 GGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINE 1386
Query: 1225 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
C +S C N TCVD++ YSC C PGF G+RCE
Sbjct: 1387 C--------QSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 234 bits (598), Expect = 6e-61
Identities = 152/455 (33%), Positives = 198/455 (43%), Gaps = 54/455 (11%)
Query: 933 CLPG--FRGTFCEE-------DINECASDPCRNGANCTDCVDSYTCTCPAGF--SGIHCE 981
C PG RG C ++ + CR G+ + CP+G IH
Sbjct: 988 CRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIH-S 1046
Query: 982 NNTPDCTESSCFNG---------------GTCVDGINSFTCLCPPGFTGSYCQHDVN-EC 1025
N DC ++ C G GT S +CL P T + + VN
Sbjct: 1047 RNISDC-KAQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISA 1105
Query: 1026 DSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCEC 1085
PC G + G CP+ Y PN +C + P + + C
Sbjct: 1106 CGVPCPEGKFSRSGLMPCH-PCPRDYYQPNAGKA--FCLACPFYGTTPFAGSRSITECSS 1162
Query: 1086 PSGWTGLYCD--VPSVSC-------EVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAG 1136
S + VP S E+++Q C + G C G + C C G
Sbjct: 1163 FSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLG 1222
Query: 1137 YTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGG 1196
YTG CE +DECSP PC N C D +G + C+C +GY G C E I+EC S PC N G
Sbjct: 1223 YTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKG 1282
Query: 1197 TCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1256
C+D Y+C+C +G G+HCE V++C +S C NN C DQVGG+ C CP
Sbjct: 1283 ICVDGVAGYRCTCVKGFVGLHCETEVNEC--------QSNPCLNNAVCEDQVGGFLCKCP 1334
Query: 1257 PGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPC 1316
PGF+G RC +V+ECLS PC T C N F C C AG TG CE IN C+ PC
Sbjct: 1335 PGFLGTRCGKNVDECLSQPCKNGAT--CKDGANSFRCLCAAGFTGSHCELNINECQSNPC 1392
Query: 1317 KNGGTCAVASNTARGFICKCPAGFEGATCENDART 1351
+N TC N+ + CKC GF G CE + T
Sbjct: 1393 RNQATCVDELNS---YSCKCQPGFSGKRCETEQST 1424
Score = 227 bits (578), Expect = 1e-58
Identities = 99/238 (41%), Positives = 137/238 (57%), Gaps = 5/238 (2%)
Query: 330 EDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCD 388
E S+ +C C + TC + C CP G TGL C + D C PC C
Sbjct: 1188 EISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVC- 1246
Query: 389 TNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPR 448
+ G+ IC CPSGYTG C ++++ECS ++PC + G C++ + + C C++G+ G
Sbjct: 1247 -KDLVGEFICECPSGYTGQRCEENINECS--SSPCLNKGICVDGVAGYRCTCVKGFVGLH 1303
Query: 449 CEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
CE +VNEC SNPC N+A C DQ+G F C C PG+ G C N DEC S PC + C D
Sbjct: 1304 CETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG 1363
Query: 509 INEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVD 566
N F+C C GFTG C+ +++EC S PC+N A C+D N+Y+C C G++G CE +
Sbjct: 1364 ANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 212 bits (540), Expect = 3e-54
Identities = 147/476 (30%), Positives = 193/476 (40%), Gaps = 84/476 (17%)
Query: 973 AGFSGIHCENNTPDCTESSCFNGGTCVD-------GINSFTC------------------ 1007
A + + + +P C S G CV+ + FTC
Sbjct: 974 ADSNSLETKKASPFCRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECK 1033
Query: 1008 LCPPGFTGSYCQ-HDVNECDSQPCLHGGTCQDGCGSYR----C-TCPQGYTGP-----NC 1056
LCP G Y ++++C +Q C+ G SY C +CP G P +C
Sbjct: 1034 LCPSGMYTEYIHSRNISDCKAQ-------CKQGTYSYSGLETCESCPLGTYQPKFGSRSC 1086
Query: 1057 QNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC--EVAAQRQGVDVAR 1114
+ ++S K G + CP G +P C + G
Sbjct: 1087 LSCPE--NTSTVKRGAV---NISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCL 1141
Query: 1115 LCQHGGLCVDAGNTHHCRCQA-GYTGSYCEDLV--------------------DECSPSP 1153
C G AG+ C + T S E+ V EC +P
Sbjct: 1142 ACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNP 1201
Query: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGT 1213
C N TC GY C C GY G+ C +IDEC PC N G C DL + C CP G
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1261
Query: 1214 QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLS 1273
G CE N+++C+ S C N G CVD V GY CTC GFVG CE +VNEC S
Sbjct: 1262 TGQRCEENINECS--------SSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Query: 1274 NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI 1333
NPC C +V F C+C G G RC ++ C +PCKNG TC +N+ R
Sbjct: 1314 NPCLNNAV--CEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR--- 1368
Query: 1334 CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASS 1389
C C AGF G+ CE + C S C N TC+ S +C C F+G C+ S+
Sbjct: 1369 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQST 1424
Score = 211 bits (537), Expect = 7e-54
Identities = 94/226 (41%), Positives = 130/226 (57%), Gaps = 9/226 (3%)
Query: 304 NACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPH 363
N C N GTC GY C+C G+TG C +ID+C+ C + C D V F CECP
Sbjct: 1200 NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPS 1259
Query: 364 GRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKA--ICTCPSGYTGPACSQDVDECSLGA 420
G TG C N + C S+PC C V+G A CTC G+ G C +V+EC +
Sbjct: 1260 GYTGQRCEENINECSSSPCLNKGIC----VDGVAGYRCTCVKGFVGLHCETEVNECQ--S 1313
Query: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP 480
NPC + C + +G F C+C G+ G RC +V+EC+S PC+N ATC D F+C+C
Sbjct: 1314 NPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAA 1373
Query: 481 GYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQ 526
G+ G HCE+N +EC S+PC + C+D++N + C+C GF+G C+
Sbjct: 1374 GFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 197 bits (502), Expect = 8e-50
Identities = 90/234 (38%), Positives = 122/234 (52%), Gaps = 5/234 (2%)
Query: 137 SCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCH 196
S Q C NPC N G C Y+C CP + G C D++EC P C + G C
Sbjct: 1190 SSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLP--CLNNGVCK 1247
Query: 197 NEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEE 256
+ VG + C C + +TG CE CS SPC N G C G + C C+ GF G +CE
Sbjct: 1248 DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCET 1306
Query: 257 NIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTH 316
+++C N C N C D V + C+CPP + G C ++VDEC P C+NG TC +
Sbjct: 1307 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGA 1364
Query: 317 GGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLC 370
+ C+C G+TG C NI++C S C + ATC D + S+ C+C G +G C
Sbjct: 1365 NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 192 bits (488), Expect = 4e-48
Identities = 90/231 (38%), Positives = 126/231 (54%), Gaps = 10/231 (4%)
Query: 63 CLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTL 122
C PC N+GTC + R Y C C LG++G C T +D C PC N G C L +
Sbjct: 1197 CFFNPCHNSGTCQQLGR----GYVCLCPLGYTGLKCETDIDE-CSPLPCLNNGVCKDL-V 1250
Query: 123 TEYKCRCPPGWSGKSCQQ-ADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNE 181
E+ C CP G++G+ C++ + C+S+PC N G C+ A Y C C F G C +VNE
Sbjct: 1251 GEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNE 1310
Query: 182 CGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTH 241
C P C + C ++VG + C C G C + C PC+NG TC+ G +
Sbjct: 1311 CQSNP--CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK-DGANSF 1367
Query: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC 292
C C GFTG +CE NI++C N C+N CVD +N+Y+C+C P ++G+ C
Sbjct: 1368 RCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 191 bits (485), Expect = 8e-48
Identities = 97/239 (40%), Positives = 126/239 (52%), Gaps = 12/239 (5%)
Query: 177 QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPT 236
Q +EC P C + GTC Y C+C +TG CE CSP PC N G C+
Sbjct: 1192 QVFHECFFNP--CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCK-- 1247
Query: 237 GDVTHE--CACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTE 294
D+ E C C G+TGQ CEENI++C + C N G CVDGV Y C C + G +C
Sbjct: 1248 -DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET 1306
Query: 295 DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRV 354
+V+ECQ N C N C + GG+ C C G+ G C +N+D+C S C +GATC D
Sbjct: 1307 EVNECQ--SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGA 1364
Query: 355 ASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQD 412
SF C C G TG C LN + C SNPC + C + +N + C C G++G C +
Sbjct: 1365 NSFRCLCAAGFTGSHCELNINECQSNPCRNQATC-VDELNSYS-CKCQPGFSGKRCETE 1421
Score = 189 bits (481), Expect = 2e-47
Identities = 87/229 (37%), Positives = 116/229 (50%), Gaps = 9/229 (3%)
Query: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYIC 164
C NPC N GTC L Y C CP G++G C+ D C+ PC N G C +IC
Sbjct: 1197 CFFNPCHNSGTCQQLG-RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 165 HCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSP 224
CP + G C +++NEC P C + G C + V YRC C G +CE C
Sbjct: 1256 ECPSGYTGQRCEENINECSSSP--CLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Query: 225 SPCQNGGTCR-PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRC 283
+PC N C G C C PGF G C +N+D+C CKNG C DG N++ C C
Sbjct: 1314 NPCLNNAVCEDQVGGFL--CKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLC 1371
Query: 284 PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDC 332
+TG +C +++ECQ N C+N TC + Y+C C G++G+ C
Sbjct: 1372 AAGFTGSHCELNINECQ--SNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 162 bits (411), Expect = 3e-39
Identities = 79/227 (34%), Positives = 119/227 (52%), Gaps = 11/227 (4%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
C N G C+ C+C + G +C+ D + C PC N G C + V ++ C C
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDL----VGEFICEC 1257
Query: 90 ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP 148
G++G C + N C ++PC N G C + + Y+C C G+ G C+ + + C SNP
Sbjct: 1258 PSGYTGQRCEENI-NECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCETEVNECQSNP 1315
Query: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
C N C ++C CPP F G C ++V+EC +P C++G TC + S+RC+C A
Sbjct: 1316 CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFRCLCAA 1373
Query: 209 THTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
TG +CE C +PC+N TC + ++ C C PGF+G+ CE
Sbjct: 1374 GFTGSHCELNINECQSNPCRNQATCVDELN-SYSCKCQPGFSGKRCE 1419
Score = 142 bits (359), Expect = 3e-33
Identities = 75/190 (39%), Positives = 91/190 (47%), Gaps = 9/190 (4%)
Query: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1297
C N+GTC GY C CP G+ G +CE D++EC PC G C V +F CEC +
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGV--CKDLVGEFICECPS 1259
Query: 1298 GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRC 1357
G+TG+RCE IN C PC N G C + G+ C C GF G CE + C S C
Sbjct: 1260 GYTGQRCEENINECSSSPCLNKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQSNPC 1316
Query: 1358 LNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCP 1417
LN C C C F G C CL PC N TC+ + S +RCLC
Sbjct: 1317 LNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDE-CLS-QPCKNGATCKDGANS--FRCLCA 1372
Query: 1418 AKFNGLLCHI 1427
A F G C +
Sbjct: 1373 AGFTGSHCEL 1382
Score = 125 bits (314), Expect = 5e-28
Identities = 116/448 (25%), Positives = 166/448 (37%), Gaps = 81/448 (18%)
Query: 1119 GGLCVDAG-----NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYS---CK 1170
G +CV+ N H C++ GSY +D + C +G T+Y+ + CK
Sbjct: 996 GRMCVNCPLGTYYNLEHFTCESCRIGSY-QDEEGQLECKLCPSGMY-TEYIHSRNISDCK 1053
Query: 1171 --CVAGYHGVNCSEEIDEC---LSHPCQNGGTCLDLP-----------NTYKCSCPRGTQ 1214
C G + + E + C P +CL P N C P +
Sbjct: 1054 AQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISACGVPC-PE 1112
Query: 1215 GVHCEINVDDCNP-PVD---PVSRSPKC----------FNNGTCVDQVGGYSCT------ 1254
G + C+P P D P + C F + + +S T
Sbjct: 1113 GKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEE 1172
Query: 1255 --CPPGFVG------ERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCES 1306
PP +G E +EC NPC GT C Q + C C G+TG +CE+
Sbjct: 1173 SVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGT--CQQLGRGYVCLCPLGYTGLKCET 1230
Query: 1307 VINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISG 1366
I+ C PC N G C + FIC+CP+G+ G CE + C S CLN G C+ G
Sbjct: 1231 DIDECSPLPCLNNGVC---KDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDG 1287
Query: 1367 PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCH 1426
C C+ F G C+ + NPC N CE + + C CP F G C
Sbjct: 1288 VAGYRCTCVKGFVGLHCETEVNE--CQSNPCLNNAVCE--DQVGGFLCKCPPGFLGTRC- 1342
Query: 1427 ILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDP 1486
G+++ L + C++ A + C A G+ G C LN N+
Sbjct: 1343 ----------GKNVDECLSQPCKNGATCKDGANSFRCLC-----AAGFTGSHCELNINEC 1387
Query: 1487 WKN-CTQSLQCWKYFSDGHCDSQCNSAG 1513
N C C + C Q +G
Sbjct: 1388 QSNPCRNQATCVDELNSYSCKCQPGFSG 1415
Score = 103 bits (256), Expect = 3e-21
Identities = 63/187 (33%), Positives = 80/187 (42%), Gaps = 44/187 (23%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDP-NPCLSTPCKNAGTCHVVDRRGVADYACSC 89
CLN G C+ G C C + G RC++ N C S+PC N G C VD GVA Y C+C
Sbjct: 1240 CLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGIC--VD--GVAGYRCTC 1295
Query: 90 ALGFSGPLCLTP---------LDNA----------------------------CLTNPCR 112
GF G C T L+NA CL+ PC+
Sbjct: 1296 VKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCK 1355
Query: 113 NGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFH 171
NG TC ++C C G++G C+ + C SNPC N C+ SY C C P F
Sbjct: 1356 NGATCKD-GANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFS 1414
Query: 172 GPTCRQD 178
G C +
Sbjct: 1415 GKRCETE 1421
Score = 82.4 bits (202), Expect = 5e-15
Identities = 48/109 (44%), Positives = 56/109 (51%), Gaps = 20/109 (18%)
Query: 226 PCQNGGTC-RPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCP 284
PCQNGG C RP C+C G+ G+ CEE I P C NGG CV Y C CP
Sbjct: 3475 PCQNGGICQRPNA-----CSCPEGWMGRLCEEPICILP---CLNGGRCVA---PYQCDCP 3523
Query: 285 PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS 333
P WTG C V CQ + C NGG C + C C++ WTG +CS
Sbjct: 3524 PGWTGSRCHTAV--CQ---SPCLNGGKCVRPN---RCHCLSSWTGHNCS 3564
Score = 81.3 bits (199), Expect = 1e-14
Identities = 51/133 (38%), Positives = 63/133 (47%), Gaps = 24/133 (18%)
Query: 92 GFSGPLCLT-------PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPC 144
GF +CL P+ A PC+NGG C C CP GW G+ C++ P
Sbjct: 3450 GFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQ----RPNACSCPEGWMGRLCEE--PI 3503
Query: 145 ASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRC 204
PC NGG+C+ A Y C CPP + G C V C Q P C +GG C V RC
Sbjct: 3504 CILPCLNGGRCV---APYQCDCPPGWTGSRCHTAV--C-QSP--CLNGGKC---VRPNRC 3552
Query: 205 VCRATHTGPNCER 217
C ++ TG NC R
Sbjct: 3553 HCLSSWTGHNCSR 3565
Score = 79.7 bits (195), Expect = 3e-14
Identities = 43/109 (39%), Positives = 55/109 (50%), Gaps = 20/109 (18%)
Query: 67 PCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYK 126
PC+N G C + ACSC G+ G LC P+ C+ PC NGG C + Y+
Sbjct: 3475 PCQNGGICQRPN-------ACSCPEGWMGRLCEEPI---CIL-PCLNGGRC----VAPYQ 3519
Query: 127 CRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTC 175
C CPPGW+G C A +PC NGG+C+ CHC S+ G C
Sbjct: 3520 CDCPPGWTGSRCHTA--VCQSPCLNGGKCV---RPNRCHCLSSWTGHNC 3563
Score = 74.7 bits (182), Expect = 1e-12
Identities = 236/1033 (22%), Positives = 316/1033 (30%), Gaps = 255/1033 (24%)
Query: 377 ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINT-LGS 435
+S CN G NPV IC + G A S EC L P + T +GS
Sbjct: 2681 VSYTCNPGYELLGNPV---LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGS 2737
Query: 436 ---FECQ------------CLQGY----TGPRCEIDVNECVSNPCQNDA---TCLDQIGE 473
+ C+ CL+ PRCE ++ NP N + + +
Sbjct: 2738 AVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEA-ISCKKPNPVMNGSIKGSNYTYLST 2796
Query: 474 FQCICMPGY-----EGVHCE--VNTDE---------CASSPCLHNGRCLDKINEFQCE-- 515
C PGY E C+ N DE C+S P NG+ FQ E
Sbjct: 2797 LYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIE 2856
Query: 516 --CPTGFT-----GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYT-GTHCEVDI 567
C GF +C + +TP +C P V TEG G EV
Sbjct: 2857 YTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGV-TEGLDYGFMKEVTF 2915
Query: 568 DECDPDPCHYGSCKDGVATFTC-----------LCRPGYTGHHCETNINECSSQPCRHGG 616
CH G G TC LC+P G + + HGG
Sbjct: 2916 H------CHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGG 2969
Query: 617 TCQDRDNAYLCFC---LKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYT-- 671
Q Y CF L G + C N SSP +CL C C
Sbjct: 2970 HIQ-----YQCFPGYKLHGNSSRRCLSNGSWSGSSP----SCLP------CRCSTPVIEY 3014
Query: 672 GSMCNINID--ECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729
G++ + D + A C G G++ TC + E C S P + A
Sbjct: 3015 GTVNGTDFDCGKAARIQCFKGFKLL-GLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNA 3073
Query: 730 CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ 789
+ +K + + C S + G +S +CT + +S P
Sbjct: 3074 FISETSSWKEN-----------VITYSCRSGYVIQG------SSDLICTEKGVWSQPYPV 3116
Query: 790 TNINECASNPCLNQGTCIDDVAGY----KCNCLLPYTGATCEVVLAPCAPSPCRNGGECR 845
C S P + + Y K CL YT T
Sbjct: 3117 CEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDT-------------------- 3156
Query: 846 QSEDYESFSCVCPTGWQGQTCEVDINECVLSP-----CRHGASCQNTHGGYRCHCQAGYS 900
D ++F+C W + +C L HG + + C GY+
Sbjct: 3157 ---DTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDF-SVNRQVSVSCAEGYT 3212
Query: 901 --GRN---CETD--------IDDCRPNPCHNGGSCTDGI---------NTAFCDCLPGF- 937
G N C+ D + C P C S G +T C PG+
Sbjct: 3213 FEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYE 3272
Query: 938 ----RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSG--IHCENNTPDCTESS 991
R C+E+ R + C P F EN T
Sbjct: 3273 LEGNRERVCQEN---------RQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVY 3323
Query: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY 1051
N G ++G + C H V C PC P+
Sbjct: 3324 SCNRGYSLEGPSEAHCT-----ENGTWSHPVPLCKPNPC-----------PVPFVIPENA 3367
Query: 1052 TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVD 1111
+ V S C+ G Q H C WT +SC A +
Sbjct: 3368 LLSEKEFYVDQNVSIKCREGFLL-QGHGIITCNPDETWTQTSAKCEKISCGPPAHVENA- 3425
Query: 1112 VARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKC 1171
+AR G+ G+ C +GY +++ S C T T C+
Sbjct: 3426 IAR-----GVHYQYGDMITYSCYSGY-------MLEGFLRSVCLENGTWTS---PPICRA 3470
Query: 1172 VAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDP 1231
V + PCQNGG C PN CSCP G G CE +P
Sbjct: 3471 VCRF---------------PCQNGGIC-QRPNA--CSCPEGWMGRLCE----------EP 3502
Query: 1232 VSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDF 1291
+ P C N G CV Y C CPPG+ G RC V +PC G CV R N
Sbjct: 3503 ICILP-CLNGGRCV---APYQCDCPPGWTGSRCHTAV---CQSPCLNGG--KCV-RPN-- 3550
Query: 1292 HCECRAGHTGRRC 1304
C C + TG C
Sbjct: 3551 RCHCLSSWTGHNC 3563
Score = 67.0 bits (162), Expect = 2e-10
Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 25/117 (21%)
Query: 1067 PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG 1126
PC+NGG C + + C CP GW G C+ P C +GG CV
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCEEPICILP-------------CLNGGRCVAP- 3517
Query: 1127 NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE 1183
+ C C G+TGS C V + SPC NG C + C C++ + G NCS +
Sbjct: 3518 --YQCDCPPGWTGSRCHTAVCQ---SPCLNGGKC---VRPNRCHCLSSWTGHNCSRK 3566
Score = 66.6 bits (161), Expect = 3e-10
Identities = 40/106 (37%), Positives = 47/106 (44%), Gaps = 16/106 (15%)
Query: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGR 365
CQNGG C + C C GW G C E I C +G C VA + C+CP G
Sbjct: 3476 CQNGGICQRPNA---CSCPEGWMGRLCEEPI---CILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 366 TGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ 411
TG CH A +PC G C P C C S +TG CS+
Sbjct: 3527 TGSRCH--TAVCQSPCLNGGKC-VRPNR----CHCLSSWTGHNCSR 3565
Score = 60.8 bits (146), Expect = 2e-08
Identities = 38/108 (35%), Positives = 47/108 (43%), Gaps = 20/108 (18%)
Query: 148 PCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCR 207
PC NGG C + C CP + G C + + C +GG C V Y+C C
Sbjct: 3475 PCQNGGIC---QRPNACSCPEGWMGRLCEEPICILP-----CLNGGRC---VAPYQCDCP 3523
Query: 208 ATHTGPNCERPYVPCSPSPCQNGGTC-RPTGDVTHECACLPGFTGQNC 254
TG C + SPC NGG C RP + C CL +TG NC
Sbjct: 3524 PGWTGSRC---HTAVCQSPCLNGGKCVRP-----NRCHCLSSWTGHNC 3563
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/101 (34%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 1315 PCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLC 1374
PC+NGG C R C CP G+ G CE L CLNGG C++ + C C
Sbjct: 3475 PCQNGGICQ------RPNACSCPEGWMGRLCEEPICI---LPCLNGGRCVAPYQ---CDC 3522
Query: 1375 LGPFTGPECQFPA-SSPCLGGNPCYNQGTCEPTSESPFYRC 1414
+TG C SPCL G C C S + C
Sbjct: 3523 PPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3563
Score = 57.0 bits (136), Expect = 2e-07
Identities = 43/127 (33%), Positives = 58/127 (45%), Gaps = 22/127 (17%)
Query: 1226 NPPV-DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNC 1284
+PP+ V R P C N G C +C+CP G++G CE + C+ PC G C
Sbjct: 3464 SPPICRAVCRFP-CQNGGICQRP---NACSCPEGWMGRLCEEPI--CIL-PCLNGG--RC 3514
Query: 1285 VQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGAT 1344
V + C+C G TG RC + + C+ PC NGG C R C C + + G
Sbjct: 3515 VA---PYQCDCPPGWTGSRCHTAV--CQ-SPCLNGGKC------VRPNRCHCLSSWTGHN 3562
Query: 1345 CENDART 1351
C RT
Sbjct: 3563 CSRKRRT 3569
Score = 41.6 bits (96), Expect = 0.010
Identities = 47/179 (26%), Positives = 64/179 (35%), Gaps = 21/179 (11%)
Query: 107 LTNPCRNGGTCDLLTLTEYKCRCPPGWSG--KSCQQADPCA-SNPCANGGQCLPFEASYI 163
+T C NG LL + C W+G SC D CA + C+ CL + SYI
Sbjct: 1712 VTYQCNNGYY--LLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYI 1769
Query: 164 CHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS 223
C C P + G D C + P C+ G N S +C+ Y
Sbjct: 1770 CSCVPPYTG-----DGKNCAE-PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMG 1823
Query: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVN-TYNC 281
+ TC +G+ H +P +C + P N C A G TY C
Sbjct: 1824 VTKI----TCLESGEWNH---LIPYCKAVSCGK--PAIPENGCIEELAFTFGSKVTYRC 1873
Score = 41.6 bits (96), Expect = 0.010
Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 9/92 (9%)
Query: 855 CVCPTGWQGQTCE-VDINECVL-SPCRHGASCQNTHGGYRCHCQAGYS--GRNCETDIDD 910
C W G + +D++EC + S C ASC N G Y C C Y+ G+NC I
Sbjct: 1730 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKC 1789
Query: 911 CRPNPCHNGGSC----TDGINTAFCDCLPGFR 938
P NG S T G F C G++
Sbjct: 1790 KAPGNPENGHSSGEIYTVGAEVTF-SCQEGYQ 1820
Score = 39.7 bits (91), Expect = 0.038
Identities = 58/245 (23%), Positives = 87/245 (35%), Gaps = 53/245 (21%)
Query: 172 GPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPY------VPCSPS 225
G + D+ C LC G C + +GS +C H CE+ Y C+
Sbjct: 267 GSFIQDDMVHCSY---LCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTAC 323
Query: 226 PCQNGGTCRPTGDVTHECACLPGFTGQNC-EENIDDCPGNNCKNGGACVDGVNTYNCRCP 284
P GT +P G +C+P C +EN PG+ C +G
Sbjct: 324 P---SGTYKPEGSPGGISSCIP------CPDENHTSPPGSTSPEDCVCREGYRA------ 368
Query: 285 PEWTGQYCTEDVDECQLMPNACQNGGTCHNT-HGGYNCVC-VNGWTGED-CSENIDDCAS 341
+GQ C ++ C + +NG NT + +N C V G D +I C
Sbjct: 369 ---SGQTC--ELVHCPAL-KPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLP 422
Query: 342 AACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAIC--T 399
+ G+ + RV + CPH + P + +C T + K C
Sbjct: 423 NGLWSGSESYCRVRT----CPH-------------LRQPKHGHISCSTREMLYKTTCLVA 465
Query: 400 CPSGY 404
C GY
Sbjct: 466 CDEGY 470
Score = 39.7 bits (91), Expect = 0.038
Identities = 96/448 (21%), Positives = 140/448 (31%), Gaps = 69/448 (15%)
Query: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPC----NEGSNCDTNPVNG 394
C+ G+ H R AS + P + L C + NP N+G P
Sbjct: 1628 CSDCPRLGGSVPHLRTASEDLK-PGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCE 1686
Query: 395 KAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYT----GPRCE 450
+ C P S D+ G+ LG C + P C
Sbjct: 1687 RISCGVPPPLENGFHS--ADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC- 1743
Query: 451 IDVNEC-VSNPCQNDATCLDQIGEFQCICMPGY--EGVHCEVNTDECASSPCLHNGRCLD 507
+DV+EC V + C A+CL+ G + C C+P Y +G +C +C + NG
Sbjct: 1744 LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNC-AEPIKCKAPGNPENGHSSG 1802
Query: 508 KINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDI 567
+I Y V + C+ G + L G TC+ + +
Sbjct: 1803 EI-----------------YTVGAEVTFSCQEGYQ-LMGVTKITCLESGEWNHLIPYCKA 1844
Query: 568 DECDPDPCHYGSCKDGVA-TF----TCLCRPGYT-----GHHCETNINECSSQPCRHGGT 617
C C + +A TF T C GYT C N + S P
Sbjct: 1845 VSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVK 1904
Query: 618 CQDRDNAYL-CFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCN 676
C +N + L G T AS CD+G L EC + +
Sbjct: 1905 CSSPENINNGKYILSGLT-------YLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPA 1957
Query: 677 INIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNG 736
++ C P N FT R Y C G L+
Sbjct: 1958 CHLVFCGEPPAIKDAVITG--NNFTFRNTVTY---------------TCKEGYTLAGLDT 2000
Query: 737 YKCDCDPGWSGTNCDINNNECESNPCVN 764
+C D WS ++ C+ P V+
Sbjct: 2001 IECLADGKWSRSDQQCLAVSCDEPPIVD 2028
Score = 39.3 bits (90), Expect = 0.050
Identities = 63/301 (20%), Positives = 96/301 (31%), Gaps = 76/301 (25%)
Query: 452 DVNECVSNPCQNDATCLDQIGEFQCICMPGY------------EGVHCEVNTDECASSPC 499
++N+ S P + L EF+ + + VHC DE C
Sbjct: 230 ELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYLCDE-GKDCC 288
Query: 500 LHNG--RCLDKINEFQCECPTGFTGHLCQYD-----------------VDECASTPCKNG 540
G +C F+C C G+ G QY+ + C P +N
Sbjct: 289 DRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENH 348
Query: 541 AKCLDGPNTYTCVCTEGY--TGTHCEVDIDECDPDP---------------------CHY 577
+ CVC EGY +G CE+ P CH
Sbjct: 349 TSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHP 408
Query: 578 GSCKDGVATFTCLCRPGYTGHHCETNINECS--SQPCRHGG-TCQDRDNAYLCFC----- 629
G G + CL ++G + C QP +HG +C R+ Y C
Sbjct: 409 GFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQP-KHGHISCSTREMLYKTTCLVACD 467
Query: 630 ----LKGTTGPNCEINLD-DCASSPCDSGTC----LDK---IDGYECACEPGYTGSMCNI 677
L+G+ C+ N D C C + K I + C +P G++C +
Sbjct: 468 EGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYV 527
Query: 678 N 678
+
Sbjct: 528 S 528
Score = 38.1 bits (87), Expect = 0.11
Identities = 37/145 (25%), Positives = 55/145 (37%), Gaps = 33/145 (22%)
Query: 213 PNCERPYVPCS-PSPCQNGGTCRPT----GDVTHECA---CLPGFTGQNCEEN------- 257
P+CER + C P P +NG VT++C L G + C +N
Sbjct: 1683 PHCER--ISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVS 1740
Query: 258 -----IDDCP-GNNCKNGGACVDGVNTYNCRCPPEWT--GQYCTEDVDECQLMPNACQNG 309
+D+C G++C +C++ +Y C C P +T G+ C E P C+
Sbjct: 1741 PSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAE--------PIKCKAP 1792
Query: 310 GTCHNTHGGYNCVCVNGWTGEDCSE 334
G N H V C E
Sbjct: 1793 GNPENGHSSGEIYTVGAEVTFSCQE 1817
Score = 37.4 bits (85), Expect = 0.19
Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
Query: 777 CTCREGFSG--PNCQTNINECA-SNPCLNQGTCIDDVAGYKCNCLLPYT--GATCEVVLA 831
CT ++G P+C +++ECA + C +C++ Y C+C+ PYT G C +
Sbjct: 1730 CTDNGSWNGVSPSC-LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIK 1788
Query: 832 PCAPSPCRNG---GECRQSEDYESFSC 855
AP NG GE +FSC
Sbjct: 1789 CKAPGNPENGHSSGEIYTVGAEVTFSC 1815
Score = 37.4 bits (85), Expect = 0.19
Identities = 25/77 (32%), Positives = 30/77 (38%), Gaps = 15/77 (19%)
Query: 22 PRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRG 81
P C P CLNGG+C A C C + G RC +PC N G C
Sbjct: 3502 PICILP---CLNGGRCVA---PYQCDCPPGWTGSRCH--TAVCQSPCLNGGKC------- 3546
Query: 82 VADYACSCALGFSGPLC 98
V C C ++G C
Sbjct: 3547 VRPNRCHCLSSWTGHNC 3563
Score = 37.0 bits (84), Expect = 0.25
Identities = 25/98 (25%), Positives = 36/98 (36%), Gaps = 26/98 (26%)
Query: 416 CSLGANPCEHAG--KCINTLGSFECQCLQGYTGPRCEID-----------------VNEC 456
C G + C+ G KC G FEC C +GY G + + ++ C
Sbjct: 281 CDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSC 340
Query: 457 VSNPCQNDATCLDQIGEFQCICMPGY-------EGVHC 487
+ P +N + C+C GY E VHC
Sbjct: 341 IPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHC 378
Score = 37.0 bits (84), Expect = 0.25
Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 20/80 (25%)
Query: 1125 AGNTHHCRCQAGY-----TGSYCEDL------------VDECSP-SPCQNGATCTDYLGG 1166
AG+T +C GY + +C D VDEC+ S C A+C + G
Sbjct: 1708 AGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGS 1767
Query: 1167 YSCKCVAGY--HGVNCSEEI 1184
Y C CV Y G NC+E I
Sbjct: 1768 YICSCVPPYTGDGKNCAEPI 1787
Score = 37.0 bits (84), Expect = 0.25
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 13/70 (18%)
Query: 1357 CLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLC 1416
C NGG C R C C + G C+ P C+ PC N G C Y+C C
Sbjct: 3476 CQNGGIC---QRPNACSCPEGWMGRLCEEPI---CI--LPCLNGGRCVAP-----YQCDC 3522
Query: 1417 PAKFNGLLCH 1426
P + G CH
Sbjct: 3523 PPGWTGSRCH 3532
Score = 35.8 bits (81), Expect = 0.56
Identities = 63/277 (22%), Positives = 83/277 (29%), Gaps = 78/277 (28%)
Query: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHA----GKCI------ 430
C+ +C G C C GY G + C G E + CI
Sbjct: 288 CDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDEN 347
Query: 431 -----NTLGSFECQCLQGY--TGPRCEI---------DVNECVSNPCQNDATCLDQIGEF 474
+ +C C +GY +G CE+ + + N C N F
Sbjct: 348 HTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNN---------HF 398
Query: 475 QCICMPGYEGVHCEVNTDECASS--PCLHNGRCLDKINEFQCECPTGFTGHLCQ--YDVD 530
C GV C D SS CL NG L +E C T HL Q +
Sbjct: 399 NAAC-----GVRCHPGFDLVGSSIILCLPNG--LWSGSESYCRVRT--CPHLRQPKHGHI 449
Query: 531 ECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCL 590
C++ CL C EGY ++ D C S DG
Sbjct: 450 SCSTREMLYKTTCL-------VACDEGYR-------LEGSDKLTCQGNSQWDGP------ 489
Query: 591 CRPGYTGHHCET---------NINECSSQPCRHGGTC 618
P HC T + + C QP + G C
Sbjct: 490 -EPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 525
Score = 35.4 bits (80), Expect = 0.73
Identities = 70/316 (22%), Positives = 104/316 (32%), Gaps = 63/316 (19%)
Query: 687 CHNGGTCEDGING--FTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744
C G+C+ G + F C C +GY+ E C S YK + PG
Sbjct: 288 CDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGT------------YKPEGSPG 335
Query: 745 WSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGF--SGPNCQTNINECAS----- 797
+ C P N + TS C CREG+ SG C+ + C +
Sbjct: 336 --------GISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCE--LVHCPALKPPE 385
Query: 798 NPCLNQGTC---IDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGE--CR------- 845
N Q TC + G +C+ G++ ++L C P+ +G E CR
Sbjct: 386 NGYFIQNTCNNHFNAACGVRCHPGFDLVGSS--IIL--CLPNGLWSGSESYCRVRTCPHL 441
Query: 846 QSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTH----GGYRC---HCQAG 898
+ + SC TC V +E +CQ RC HC
Sbjct: 442 RQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTF 501
Query: 899 YSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGA 958
++ +C P G C + C GF + +E + S G
Sbjct: 502 QMPKDVIISPHNCGKQPAKFGTIC-------YVSCRQGFILSGVKEMLRCTTSGKWNVGV 554
Query: 959 NCTDC--VDSYTCTCP 972
C V++ CP
Sbjct: 555 QAAVCKDVEAPQINCP 570
Score = 35.0 bits (79), Expect = 0.95
Identities = 45/178 (25%), Positives = 58/178 (32%), Gaps = 48/178 (26%)
Query: 1138 TGSYCEDLVDECSPSPCQNGATCTDYLGG---------YSCKCVAGYHGVNCSEEIDECL 1188
+GS+ +D + CS C G C D +G + C C GY+G E C
Sbjct: 266 SGSFIQDDMVHCSYL-CDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACP 324
Query: 1189 SHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQV 1248
S TYK P G+ G + C P D SP
Sbjct: 325 S-------------GTYK---PEGSPG-----GISSCIPCPDENHTSPP--------GST 355
Query: 1249 GGYSCTCPPGF--VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRC 1304
C C G+ G+ CE L P + QN N F+ C G RC
Sbjct: 356 SPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCN--NHFNAAC-----GVRC 406
Score = 35.0 bits (79), Expect = 0.95
Identities = 108/522 (20%), Positives = 168/522 (32%), Gaps = 123/522 (23%)
Query: 1096 VPSVSCEVAAQRQGVDVARLCQHGGLCVDAGN-THHCRCQAGYTGS--YCEDLVDECS-P 1151
VP + + G V C G V GN +C Q +T +CE + C P
Sbjct: 1638 VPHLRTASEDLKPGSKVNLFCDPGFQLV--GNPVQYCLNQGQWTQPLPHCERI--SCGVP 1693
Query: 1152 SPCQNGATCTD--YLGG-YSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS 1208
P +NG D Y G + +C GY+ + S C + G+ N S
Sbjct: 1694 PPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMF-------CTDNGSW----NGVSPS 1742
Query: 1209 CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE--RCEG 1266
C ++VD+C D C + +C++ G Y C+C P + G+ C
Sbjct: 1743 C----------LDVDECAVGSD-------CSEHASCLNVDGSYICSCVPPYTGDGKNCAE 1785
Query: 1267 DVN-ECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVA 1325
+ + NP + + + C+ G+ + G C G
Sbjct: 1786 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ-------LMGVTKITCLESGEWNHL 1838
Query: 1326 SNTARGFICKCPAGFEGATCENDARTCGS---LRCLNGGTCISGPRSPTCLCLGPFTGPE 1382
+ C PA E E A T GS RC N G ++G + +CL ++
Sbjct: 1839 IPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRC-NKGYTLAGDKESSCLANSSWS--- 1894
Query: 1383 CQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFN------GLLCHILDYSFGGGA 1436
++ CEP +C P N L ++ S+
Sbjct: 1895 ---------------HSPPVCEPV------KCSSPENINNGKYILSGLTYLSTASYSCDT 1933
Query: 1437 GRDIPPPLIEE------------ACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFN 1484
G + P I E AC L C E K + NN N
Sbjct: 1934 GYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFR----------N 1983
Query: 1485 DPWKNCTQ--------SLQCWKYFSDGHCDSQCNSAGC----LFDGFDCQRAEGQCNPLY 1532
C + +++C D QC + C + D + A +
Sbjct: 1984 TVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIA 2043
Query: 1533 DQYCKDHFSDGHCDQGCNSAECEW---DGLD---CAEHVPER 1568
YC D +S Q +A+ +W +G D C H E+
Sbjct: 2044 FYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEK 2085
Score = 33.5 bits (75), Expect = 2.8
Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 29/118 (24%)
Query: 978 IHCE---NNTPDCTESSCFNGGTCVDGINS--FTCLCPPGFTGSYCQHDVNECDSQPCLH 1032
+HC + DC C G+C G ++ F C+C G+ G Q++ C S
Sbjct: 275 VHCSYLCDEGKDC----CDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKP 330
Query: 1033 GGT---------CQD--------GCGSYRCTCPQGY--TGPNCQNLVHWCDSSPCKNG 1071
G+ C D C C +GY +G C+ LVH P +NG
Sbjct: 331 EGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCE-LVHCPALKPPENG 387
Score = 33.1 bits (74), Expect = 3.6
Identities = 35/143 (24%), Positives = 47/143 (32%), Gaps = 33/143 (23%)
Query: 741 CDPGWSGTNCDINNNECESNPCVNGGTCKDMTSG----YVCTCREGFSGPNCQTNINECA 796
C P +G NC + C+ G D T G Y C +G P T +CA
Sbjct: 740 CTPDNTGVNCTLT--------CLEG---YDFTEGSTDKYYCAYEDGVWKPTYTTEWPDCA 788
Query: 797 SNPCLNQGTCIDDVAGYKCNC----LLPYTGATCEVVLAPCAPSPCRNGG--ECRQSE-- 848
N G ++ C L+ E L PS C + +CR E
Sbjct: 789 KKRFANHGFKSFEMFYKAARCDDTDLMKKFSEAFETTLGKMVPSFCSDAEDIDCRLEENL 848
Query: 849 ----------DYESFSCVCPTGW 861
DYE+ + P GW
Sbjct: 849 TKKYCLEYNYDYENGFAIGPGGW 871
Score = 33.1 bits (74), Expect = 3.6
Identities = 52/233 (22%), Positives = 74/233 (31%), Gaps = 48/233 (20%)
Query: 907 DIDDCRP-NPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVD 965
D+D+C + C SC + + C C+P + G +G NC + +
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG----------------DGKNCAEPI- 1787
Query: 966 SYTCTCPAGFSGIHC--ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVN 1023
C P H E T + G + G+ TCL H +
Sbjct: 1788 --KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCL-----ESGEWNHLIP 1840
Query: 1024 ECDSQPCLHGGTCQDGC--------GS---YRCTCPQGYT-----GPNCQNLVHWCDSSP 1067
C + C ++GC GS YRC +GYT +C W S P
Sbjct: 1841 YCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCN--KGYTLAGDKESSCLANSSWSHSPP 1898
Query: 1068 CKNGGKCWQTHTQYRCE-CPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG 1119
KC + SG T Y S SC+ QG + G
Sbjct: 1899 VCEPVKCSSPENINNGKYILSGLT--YLSTASYSCDTGYSLQGPSIIECTASG 1949
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 270 bits (691), Expect = 1e-71
Identities = 293/1064 (27%), Positives = 417/1064 (39%), Gaps = 214/1064 (20%)
Query: 108 TNPCRNGGTCDLLTLTEYKCRCPPGW----SGKSCQQADPCASNPCANGGQCLPFEASYI 163
TN C GTC L Y+C C PG+ S C + C +PC G+C+ SY
Sbjct: 853 TNVC-GPGTCVNLP-DGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYS 910
Query: 164 CHCPPSFHGPTCR-----QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERP 218
C C P + T QD+NEC ++PG+C GG C N GSY C C++
Sbjct: 911 CFCYPGYTLATSGATQECQDINEC-EQPGVC-SGGQCTNTEGSYHC---------ECDQG 959
Query: 219 YVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT 278
Y+ CQ+ CR G CP G CV+ +
Sbjct: 960 YIMVRKGHCQDINECRHPG----------------------TCP------DGRCVNSPGS 991
Query: 279 YNC-RCPPEWTGQY-CTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW---TGEDCS 333
Y C C + GQ DV+EC L P C + G C N G + C C G+ + E
Sbjct: 992 YTCLACEEGYRGQSGSCVDVNEC-LTPGVCAH-GKCTNLEGSFRCSCEQGYEVTSDEKGC 1049
Query: 334 ENIDDCASAACFHGATCHDRVASFYCE-CPHG----RTGLLCHLNDACISNPCNEGSNCD 388
+++D+CAS A C + SF C C +G G C D C C
Sbjct: 1050 QDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVC- 1108
Query: 389 TNPVNGKAICTCPSGY----TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY 444
TN + C GY G +C +DVDEC + C G+C NT+GS++C C QG+
Sbjct: 1109 TNTAGSFSCKDCDGGYRPSPLGDSC-EDVDECEDPQSSC-LGGECKNTVGSYQCLCPQGF 1166
Query: 445 ---TGPRCEIDVNECVSNP-CQNDATCLDQIGEFQCICMPGY----EGVHCEVNTDECAS 496
G CE DVNEC+ C CL+ G F C+C PG+ G C+ + DECA+
Sbjct: 1167 QLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQ-DVDECAT 1224
Query: 497 S-PCLHNGRCLDKINEFQCECPTGF-----TGHLCQYDVDECA--STPCKNGAKCLDGPN 548
+ PC+ G C++ F C C TGF +G D+DEC P KC + P
Sbjct: 1225 TDPCV-GGHCVNTEGSFNCLCETGFQPSPESGEC--VDIDECEDYGDPVCGTWKCENSPG 1281
Query: 549 TYTCV--CTEGY---TGTHCEVDIDECDPDPC--HYGSCKDGVATFTCLCRPGY----TG 597
+Y CV C G+ C +DIDEC D +G C + +F CLC G+ +G
Sbjct: 1282 SYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSG 1340
Query: 598 HHCETNINECSSQPCRHGGT-CQDRDNAYLCFCL---------------KGTTGPN-CEI 640
C ++NEC G C++ + ++LC C +G G + E
Sbjct: 1341 WDC-VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEA 1399
Query: 641 NLDDCASSP----CDSG-----TCLDKI----DGYECACEPGYT-GSMCNINIDECAGNP 686
D A +P C SG C + EC C G + G C++
Sbjct: 1400 PTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDL--------- 1450
Query: 687 CHNGGTCEDGINGFTCRCPEG----------YHDPTCLSEVNEC---NSNPCVHGACRDS 733
C + + E F+ CP G T ++ +EC C +G C ++
Sbjct: 1451 CPSEDSAE-----FSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNT 1505
Query: 734 LNGYKCDCDPGW----SGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ 789
+ GY C C+PG+ S C+ +++EC+ C N G C + + C C P
Sbjct: 1506 VPGYVCLCNPGFHYDASHKKCE-DHDECQDLACEN-GECVNTEGSFHCFC-----SPPLT 1558
Query: 790 TNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSED 849
++++ C+N + +D+ + + + + T +V P G +E
Sbjct: 1559 LDLSQ---QRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPL------RGHRTTYTE- 1608
Query: 850 YESFSCVCPTG--WQGQ--TCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCE 905
C C G W Q C +E C G H + GY
Sbjct: 1609 -----CCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAG--VHFRPGYEYGPGP 1661
Query: 906 TDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEE-DINECASDPCRNGANCTDCV 964
D+ P +G + + P F T D P + V
Sbjct: 1662 DDLHYSIYGP--DGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYV 1719
Query: 965 DSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF---TGSYCQHD 1021
S+ PAGF G+ E +C + G CV +TC C GF D
Sbjct: 1720 ASHP-EPPAGFEGLQAE----ECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVD 1774
Query: 1022 VNECD-----SQPCLHGGTCQDGCGSYRCTCPQGYTG----PNC 1056
VNECD + C+H G C++ GSYRC C GY P+C
Sbjct: 1775 VNECDDLNGPAVLCVH-GYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 267 bits (683), Expect = 9e-71
Identities = 265/993 (26%), Positives = 399/993 (40%), Gaps = 169/993 (17%)
Query: 413 VDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEI---DVNECVSNPCQNDATCLD 469
+D C+ GA G C+N + C C GY + D NEC+ +PC+ C++
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 470 QIGEFQCICMPGY----EGVHCEV-NTDECASSPCLHNGRCLDKINEFQCECPTGFT--- 521
++G + C C PGY G E + +EC G+C + + CEC G+
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVR 964
Query: 522 -GHLCQYDVDECASTPCKNGAKCLDGPNTYTCV-CTEGYTGTHCE-VDIDEC-DPDPCHY 577
GH CQ D++EC +C++ P +YTC+ C EGY G VD++EC P C +
Sbjct: 965 KGH-CQ-DINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAH 1022
Query: 578 GSCKDGVATFTCLCRPGYTGHHCET---NINECSSQPCRHGGTCQDRDNAYLCF-CLKG- 632
G C + +F C C GY E +++EC+S+ G C + + ++ C C G
Sbjct: 1023 GKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGY 1082
Query: 633 ---TTGPNCEINLDDCA-SSPCDSGTCLDKIDGYECA-CEPGYT----GSMCNINIDECA 683
G CE +LD+CA C SG C + + C C+ GY G C ++DEC
Sbjct: 1083 WVNEDGTACE-DLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECE 1140
Query: 684 G--NPCHNGGTCEDGINGFTCRCPEGYH--DPTCLSEVNEC--NSNPCVHGACRDSLNGY 737
+ C GG C++ + + C CP+G+ + T +VNEC + HG C +S +
Sbjct: 1141 DPQSSCL-GGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSF 1199
Query: 738 KCDCDPGW----SGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQT--- 790
C C PG+ GT+C + ++PCV GG C + + C C GF P+ ++
Sbjct: 1200 FCLCAPGFVSAEGGTSCQDVDECATTDPCV-GGHCVNTEGSFNCLCETGFQ-PSPESGEC 1257
Query: 791 -NINECAS--NPCLNQGTCIDDVAGYKC--NCLLPYTGAT---CEVVLAPCA-PSPCRNG 841
+I+EC +P C + Y+C C + A C + + CA + C +
Sbjct: 1258 VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCGSH 1316
Query: 842 GECRQSEDYESFSCVCPTGWQ----GQTCEVDINECVLSPCRHGAS-CQNTHGGYRCHCQ 896
G C ++ SF C+C G++ G C VD+NEC L GA+ C+N G + C C
Sbjct: 1317 GFCDNTDG--SFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLCA 1373
Query: 897 AGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF-------CDCLPGFRGTF-CEEDINE 948
+ + + CRP GG T DC G +G C +
Sbjct: 1374 SDLEEYDAQEG--HCRPRGA--GGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGR 1429
Query: 949 CASDP---CRNGANCTDCVD--------SYTCTCPAGFSGIHCENNTP-------DCTES 990
+ C GA+ D D ++ CP+G I E D E
Sbjct: 1430 NTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADEC 1489
Query: 991 SCFNGGTCVDG-----INSFTCLCPPGF----TGSYCQHDVNECDSQPCLHGGTCQDGCG 1041
F G C +G + + CLC PGF + C+ D +EC C G C + G
Sbjct: 1490 VIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLAC-ENGECVNTEG 1547
Query: 1042 SYRCTCPQGYT----GPNCQNLVHWCDSSPCKNGGK--CWQ----------------THT 1079
S+ C C T C N + P + CW+ T+T
Sbjct: 1548 SFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYT 1607
Query: 1080 QYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH-------HCR 1132
+ C+ W+ P S EV AQ V + G+ G + H
Sbjct: 1608 ECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYS 1667
Query: 1133 CQA-------GYTGSYCEDLVDECS---------------PSPCQNGATCTDYLGGYSCK 1170
Y G ED V E + SP Q Y+ + +
Sbjct: 1668 IYGPDGAPFYNYLGP--EDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHP-E 1724
Query: 1171 CVAGYHGVNCSEEIDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV 1229
AG+ G+ + +EC + + C+NG C+ + Y C C G Q + D N
Sbjct: 1725 PPAGFEGL----QAEECGILNGCENG-RCVRVREGYTCDCFEGFQLDAAHMACVDVNECD 1779
Query: 1230 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE 1262
D + C + G C + G Y C C PG+V E
Sbjct: 1780 DLNGPAVLCVH-GYCENTEGSYRCHCSPGYVAE 1811
Score = 256 bits (655), Expect = 2e-67
Identities = 318/1251 (25%), Positives = 472/1251 (37%), Gaps = 254/1251 (20%)
Query: 129 CPPGWSGKS---CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK 185
CP G+ + CQ + C + +C+ SY+C C P R + C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSR---SRCVSD 664
Query: 186 PGLCRHGGTCHNEVGSYRC-----------VCRATHT----GPNCERPYVPCSPS----- 225
+ G C+ +G C +C + G CE+ +P + +
Sbjct: 665 KAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREIC 724
Query: 226 PCQNGGTCR-------------------PTGDVTHECACLPGFTGQNCEENIDDC---PG 263
P +G T P LPG + + D G
Sbjct: 725 PAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAG 784
Query: 264 NNCKNGGACVDGVNTYNCRCPPEWTGQYCT--------EDVDECQLMPNA---------- 305
G + V T P TG T ++ E Q+ P+
Sbjct: 785 TIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPG 844
Query: 306 ---CQNG-------GTCHNTHGGYNCVCVNGW----TGEDCSENIDDCASAACFHGATCH 351
C G GTC N GY CVC G+ + C+++ ++C C C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDD-NECLRDPCKGKGRCI 903
Query: 352 DRVASFYCECPHGRTGLLCHLNDACIS-NPCNEGSNCD----TNPVNGKAICTCPSGY-- 404
+RV S+ C C G T C N C + C TN G C C GY
Sbjct: 904 NRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTN-TEGSYHCECDQGYIM 962
Query: 405 TGPACSQDVDEC-SLGANPCEHAGKCINTLGSFEC-QCLQGYTGPRCE-IDVNECVSNPC 461
QD++EC G P G+C+N+ GS+ C C +GY G +DVNEC++
Sbjct: 963 VRKGHCQDINECRHPGTCP---DGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGV 1019
Query: 462 QNDATCLDQIGEFQCICMPGYEGVHCE---VNTDECASSPCLHNGRCLDKINEFQCE-CP 517
C + G F+C C GYE E + DECAS G CL+ F C C
Sbjct: 1020 CAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACE 1079
Query: 518 TGF----TGHLCQYDVDECASTPCKNGAKCLDGPNTYTCV-CTEGY----TGTHCEVDID 568
G+ G C+ D+DECA C + +++C C GY G CE D+D
Sbjct: 1080 NGYWVNEDGTACE-DLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVD 1137
Query: 569 ECDPDP---CHYGSCKDGVATFTCLCRPGY---TGHHCETNINEC-SSQPCRHGGTCQDR 621
EC+ DP C G CK+ V ++ CLC G+ G CE ++NEC + C G C +
Sbjct: 1138 ECE-DPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNS 1195
Query: 622 DNAYLCFCLKGTT----GPNCEINLDDCASS-PCDSGTCLDKIDGYECACEPGYTGSMCN 676
++ C C G G +C+ ++D+CA++ PC G C++ + C CE G+ S +
Sbjct: 1196 HGSFFCLCAPGFVSAEGGTSCQ-DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPES 1254
Query: 677 ---INIDECA--GNPCHNGGTCEDGINGFTC--RCPEGYH---DPTCLSEVNEC-NSNPC 725
++IDEC G+P CE+ + C C G+H + C+ +++EC N C
Sbjct: 1255 GECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCI-DIDECANDTMC 1313
Query: 726 -VHGACRDSLNGYKCDCDPGW----SGTNCDINNNECESNPCVNGGT-CKDMTSGYVCTC 779
HG C ++ ++C CD G+ SG +C ++ NECE V G C+++ ++C C
Sbjct: 1314 GSHGFCDNTDGSFRCLCDQGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLC 1372
Query: 780 ---------REGFSGPNCQ--TNINECASNPCLNQGTCIDDVAGYK----CNCLLPYTGA 824
+EG P +++E + T +D +G K C+ +L
Sbjct: 1373 ASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTT 1432
Query: 825 TCEVVLAPCAPSPCRNGGECR--QSEDYESFSCVCPTG---------WQ-GQTCEVDINE 872
E C G C SED FS +CP+G W GQT D +E
Sbjct: 1433 QAEC----CCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADE 1488
Query: 873 CVL---SPCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCRPNPCHNGGSCTDG 925
CV+ C +G C NT GY C C G+ S + CE D D+C+ C N G C +
Sbjct: 1489 CVIFGPGLCPNG-RCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACEN-GECVNT 1545
Query: 926 INTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCV---DSYTCTCPAGFSGIHC-- 980
+ C C P + + C N + T+ + D + C + C
Sbjct: 1546 EGSFHCFCSPPL--------TLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSE 1597
Query: 981 --ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ-HDVNECDSQ--------P 1029
+ TE C +G + + LCPP + Y Q +V +++ P
Sbjct: 1598 PLRGHRTTYTECCCQDG----EAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRP 1653
Query: 1030 CLHGGTCQDGCGSYRCTCPQG-----YTGPN--------CQNLVHWCDSSPCKNG----G 1072
G D Y P G Y GP H D +P
Sbjct: 1654 GYEYGPGPDDL-HYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPS 1712
Query: 1073 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCR 1132
+ + E P+G+ GL Q + + C++ G CV + C
Sbjct: 1713 ELQPHYVASHPEPPAGFEGL-------------QAEECGILNGCEN-GRCVRVREGYTCD 1758
Query: 1133 CQAGY----TGSYCEDLVDEC----SPSPCQNGATCTDYLGGYSCKCVAGY 1175
C G+ C D V+EC P+ C + G Y C C GY
Sbjct: 1759 CFEGFQLDAAHMACVD-VNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 249 bits (637), Expect = 2e-65
Identities = 274/1013 (27%), Positives = 393/1013 (38%), Gaps = 164/1013 (16%)
Query: 390 NPVNGKAICTCPSGYTGPACS--QDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGP 447
+PV CP GY + QD++EC L C+ A +C+NT GS+ C C G
Sbjct: 598 SPVIENGQLECPQGYKRLNLTHCQDINEC-LTLGLCKDA-ECVNTRGSYLCTCRPGLM-- 653
Query: 448 RCEIDVNECVSNPCQN--DATCLDQIGEFQC---ICMPGYEGVHCEVNTDECASSPCLHN 502
+ + CVS+ + C +G C + + + C + S C
Sbjct: 654 -LDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSEC--- 709
Query: 503 GRC-LDKINEFQCECPTGFTGHLCQYDV---------DECASTPCKNGAK---CLDGPNT 549
+C L F+ CP G D+ +E A P + G + L GP
Sbjct: 710 EKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALPGPAE 769
Query: 550 YTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSS 609
+ T T E PD G + G T + P + + T
Sbjct: 770 RQPLRV--VTDTWLEAGTI---PDK---GDSQAGQVTTSVTHAPAWVTGNATT-----PP 816
Query: 610 QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSP---CDSGTCLDKIDGYECAC 666
P + Q+ L + P +D CA+ C GTC++ DGY C C
Sbjct: 817 MPEQGIAEIQEEQVTPSTDVLVTLSTPG----IDRCAAGATNVCGPGTCVNLPDGYRCVC 872
Query: 667 EPGY----TGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC-----LSEV 717
PGY + + C + +EC +PC G C + + ++C C GY T ++
Sbjct: 873 SPGYQLHPSQAYCTDD-NECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDI 931
Query: 718 NECNS-NPCVHGACRDSLNGYKCDCDPGW----SGTNCDINNNECESNPCVNGGTCKDMT 772
NEC C G C ++ Y C+CD G+ G DIN EC G C +
Sbjct: 932 NECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDIN--ECRHPGTCPDGRCVNSP 989
Query: 773 SGYVC-TCREGFSGPNCQ-TNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGAT----C 826
Y C C EG+ G + ++NEC + G C + ++C+C Y + C
Sbjct: 990 GSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGC 1049
Query: 827 EVVLAPCAPSPCRNGGECRQSEDYESFSC-VCPTGW----QGQTCEVDINECVLSPCRHG 881
+ V CA G C +E SF+C C G+ G CE D++EC
Sbjct: 1050 QDV-DECASRASCPTGLCLNTEG--SFACSACENGYWVNEDGTACE-DLDECAFPGVCPS 1105
Query: 882 ASCQNTHGGYRCH-CQAGYS----GRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLP 935
C NT G + C C GY G +CE D+D+C P GG C + + + C C
Sbjct: 1106 GVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCLGGECKNTVGSYQCLCPQ 1164
Query: 936 GFR---GTFCEEDINECASDP-CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDC 987
GF+ GT CE D+NEC + C C + S+ C C GF G C++
Sbjct: 1165 GFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECA 1223
Query: 988 TESSCFNGGTCVDGINSFTCLCPPGFTGS----YCQHDVNECDS--QPCLHGGTCQDGCG 1041
T C GG CV+ SF CLC GF S C D++EC+ P C++ G
Sbjct: 1224 TTDPCV-GGHCVNTEGSFNCLCETGFQPSPESGECV-DIDECEDYGDPVCGTWKCENSPG 1281
Query: 1042 SYRCT--CPQGY-TGPN--CQNLVHWCDSSPCKNGGKCWQTHTQYRCEC-------PSGW 1089
SYRC C G+ PN C ++ + + C + G C T +RC C PSGW
Sbjct: 1282 SYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGW 1341
Query: 1090 TGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH-------HCRCQAGYTGSYC 1142
C V CE+ G + + LC+ A + HCR + S
Sbjct: 1342 D---C-VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMS 1397
Query: 1143 EDLVDECSPSP----CQNG----ATCTDYLGGYS----CKCVAGYHGVN----CSEEIDE 1186
E + +P+P C +G A C+ LG + C C G + C E
Sbjct: 1398 EAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSA 1457
Query: 1187 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVD 1246
S C +G + + + T G + D+C V P NG C++
Sbjct: 1458 EFSEICPSGKGYIPVEGAW-------TFGQTMYTDADEC------VIFGPGLCPNGRCLN 1504
Query: 1247 QVGGYSCTCPPGF----VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 1295
V GY C C PGF ++CE D +EC C+ CV FHC C
Sbjct: 1505 TVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACE---NGECVNTEGSFHCFC 1553
Score = 205 bits (521), Expect = 5e-52
Identities = 257/984 (26%), Positives = 372/984 (37%), Gaps = 215/984 (21%)
Query: 23 RCSQPGETCLNGGKCEAANGTEACVCGGAF-VGPR---CQDPNPCLSTPCKNAGTCHVVD 78
RC+ G C CVC + + P C D N CL PCK G C ++
Sbjct: 847 RCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRC--IN 904
Query: 79 RRGVADYACSCALGFSGPLCLTPLDNACL-TNPCRNGGTCD--LLTLTE--YKCRCPPGW 133
R V Y+C C G++ L + C N C G C T TE Y C C G+
Sbjct: 905 R--VGSYSCFCYPGYT--LATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGY 960
Query: 134 ---SGKSCQQADPCASNPCANGGQCLPFEASYIC-HCPPSFHGPT-CRQDVNECGQKPGL 188
CQ + C G+C+ SY C C + G + DVNEC PG+
Sbjct: 961 IMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGV 1019
Query: 189 CRHGGTCHNEVGSYRCVC----RATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECA 244
C H G C N GS+RC C T C+ S + C G C T A
Sbjct: 1020 CAH-GKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPT-GLCLNTEGSFACSA 1077
Query: 245 CLPGF----TGQNCEENIDDCPGNNCKNGGACVDGVNTYNCR-CP----PEWTGQYCTED 295
C G+ G CE+ +D+C G C + +++C+ C P G C ED
Sbjct: 1078 CENGYWVNEDGTACED-LDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSC-ED 1135
Query: 296 VDECQLMPNACQNGGTCHNTHGGYNCVCVNGW---TGEDCSENIDDC-ASAACFHGATCH 351
VDEC+ ++C GG C NT G Y C+C G+ G C E++++C C C
Sbjct: 1136 VDECEDPQSSCL-GGECKNTVGSYQCLCPQGFQLANGTVC-EDVNECMGEEHCAPHGECL 1193
Query: 352 DRVASFYCECPHG----RTGLLCHLNDAC-ISNPCNEGSNCDTNPVNGKAICTCPSGY-T 405
+ SF+C C G G C D C ++PC G +T G C C +G+
Sbjct: 1194 NSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNT---EGSFNCLCETGFQP 1250
Query: 406 GPACSQ--DVDECSLGANPCEHAGKCINTLGSFEC--QCLQGY-TGPRCE-IDVNECVSN 459
P + D+DEC +P KC N+ GS+ C C G+ P + ID++EC ++
Sbjct: 1251 SPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECAND 1310
Query: 460 P-CQNDATCLDQIGEFQCICMPGYE----GVHC-EVNTDECASSPCLHNGRCLDKINEFQ 513
C + C + G F+C+C G+E G C +VN E + C C + F
Sbjct: 1311 TMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVC-GAALCENVEGSFL 1369
Query: 514 CECPTGFTGHLCQYDVDECASTP------------------------CKNGAK------C 543
C C L +YD E P C +G K
Sbjct: 1370 CLC----ASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSS 1425
Query: 544 LDGPNT--YTCVCTEGYT-GTHCEV----------------------------------D 566
+ G NT C CT+G + G C++ D
Sbjct: 1426 VLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTD 1485
Query: 567 IDEC---DPDPCHYGSCKDGVATFTCLCRPG--YTGHH--CETNINECSSQPCRHGGTCQ 619
DEC P C G C + V + CLC PG Y H CE + +EC C + G C
Sbjct: 1486 ADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDH-DECQDLACEN-GECV 1543
Query: 620 DRDNAYLCF-------------CLKGTTG----PNCEINLDDCASSPCDSGTCLDKIDGY 662
+ + ++ CF C+ T+ P+ +I++D C + C + + G+
Sbjct: 1544 NTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKK-VTNDVCSEPLRGH 1602
Query: 663 -----ECACEPGYTGS----------------MCN---INIDECAG---NPCHNGGTCED 695
EC C+ G S +CN I + AG P + G D
Sbjct: 1603 RTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPD 1662
Query: 696 GINGFTCRCPEGYHDPTCLSEVNECNS----NPCVHGACRDSLNG---YKCDCDPGWSGT 748
++ ++ P+G L + N H A R + + P + +
Sbjct: 1663 DLH-YSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVAS 1721
Query: 749 NCD-------INNNECE-SNPCVNGGTCKDMTSGYVCTCREGF---SGPNCQTNINEC-- 795
+ + + EC N C N G C + GY C C EGF + ++NEC
Sbjct: 1722 HPEPPAGFEGLQAEECGILNGCEN-GRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDD 1780
Query: 796 ASNPCL--NQGTCIDDVAGYKCNC 817
+ P + G C + Y+C+C
Sbjct: 1781 LNGPAVLCVHGYCENTEGSYRCHC 1804
Score = 195 bits (496), Expect = 4e-49
Identities = 202/725 (27%), Positives = 289/725 (39%), Gaps = 136/725 (18%)
Query: 766 GTCKDMTSGYVCTCREGFSGPNCQ---TNINECASNPCLNQGTCIDDVAGYKCNCLLPYT 822
GTC ++ GY C C G+ Q T+ NEC +PC +G CI+ V Y C C YT
Sbjct: 859 GTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYT 918
Query: 823 GAT------CEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGW---QGQTCEVDINEC 873
AT C+ + P C +GG+C +E S+ C C G+ + C+ DINEC
Sbjct: 919 LATSGATQECQDINECEQPGVC-SGGQCTNTEG--SYHCECDQGYIMVRKGHCQ-DINEC 974
Query: 874 VLSPCRHGASCQNTHGGYRC-HCQAGYSGRNCE-TDIDDC-RPNPCHNGGSCTDGINTAF 930
C N+ G Y C C+ GY G++ D+++C P C +G CT+ +
Sbjct: 975 RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFR 1033
Query: 931 CDCLPGFRGTFCE---EDINECASDPCRNGANCTDCVDSYTCT-CPAGF----SGIHCEN 982
C C G+ T E +D++ECAS C + S+ C+ C G+ G CE+
Sbjct: 1034 CSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACED 1093
Query: 983 NTPDCTESSCFNGGTCVDGINSFTCL-CPPGFT----GSYCQHDVNEC-DSQPCLHGGTC 1036
+C G C + SF+C C G+ G C+ DV+EC D Q GG C
Sbjct: 1094 -LDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCLGGEC 1151
Query: 1037 QDGCGSYRCTCPQGY---TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLY 1093
++ GSY+C CPQG+ G C+++ C G+C +H + C C G+
Sbjct: 1152 KNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGF---- 1207
Query: 1094 CDVPSVSCEVAAQRQGVDVARLCQH--GGLCVDAGNTHHCRCQAGYTGS----YCEDLVD 1147
VS E Q VD GG CV+ + +C C+ G+ S C D +D
Sbjct: 1208 -----VSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVD-ID 1261
Query: 1148 ECSP--SPCQNGATCTDYLGGYSCK--CVAGYHGVNCSE--EIDECLSHP-CQNGGTCLD 1200
EC P C + G Y C C G+H + +IDEC + C + G C +
Sbjct: 1262 ECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDN 1321
Query: 1201 LPNTYKCSC-------PRGTQGV---HCEINVDDCNPPV-DPVSRSPKCF---------- 1239
+++C C P G V CE+ + C + + V S C
Sbjct: 1322 TDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDA 1381
Query: 1240 NNGTCVDQ-VGGYSCTCPPGFVGERCEGDVN-ECLSN-----PCDARGTQNCVQRVNDFH 1292
G C + GG S + P G+ +C S PC + +N Q
Sbjct: 1382 QEGHCRPRGAGGQSMSEAP--TGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQA----E 1435
Query: 1293 CECRAGHT-GRRCE-----------SVINGCKGK-PCKNGGT-----------CAVAS-- 1326
C C G + G C+ + KG P + T C +
Sbjct: 1436 CCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPG 1495
Query: 1327 --------NTARGFICKCPAGF----EGATCENDARTCGSLRCLNGGTCISGPRSPTCLC 1374
NT G++C C GF CE D C L C N G C++ S C C
Sbjct: 1496 LCPNGRCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACEN-GECVNTEGSFHCFC 1553
Query: 1375 LGPFT 1379
P T
Sbjct: 1554 SPPLT 1558
Score = 151 bits (382), Expect = 7e-36
Identities = 149/564 (26%), Positives = 212/564 (37%), Gaps = 108/564 (19%)
Query: 1034 GTCQDGCGSYRCTCPQGYTGPNCQNLV---HWCDSSPCKNGGKCWQTHTQYRCECPSGWT 1090
GTC + YRC C GY Q + C PCK G+C Y C C G+T
Sbjct: 859 GTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYT 918
Query: 1091 GLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT---GSYCEDLVD 1147
L + C+ + + V GG C + ++HC C GY +C+D+ +
Sbjct: 919 -LATSGATQECQDINECEQPGVCS----GGQCTNTEGSYHCECDQGYIMVRKGHCQDINE 973
Query: 1148 ECSPSPCQNGATCTDYLGGYSC-KCVAGYHGVNCS-EEIDECLSHPCQNGGTCLDLPNTY 1205
P C +G C + G Y+C C GY G + S +++ECL+ G C +L ++
Sbjct: 974 CRHPGTCPDGR-CVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSF 1032
Query: 1206 KCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT-CPPGFV---- 1260
+CSC +G + E D VD + C G C++ G ++C+ C G+
Sbjct: 1033 RCSCEQGYEVTSDEKGCQD----VDECASRASC-PTGLCLNTEGSFACSACENGYWVNED 1087
Query: 1261 GERCEGDVNECLSNPCDARGTQNCVQRVNDFHC-ECRAGHT----GRRCESVINGCKGKP 1315
G CE D++EC G C F C +C G+ G CE V +
Sbjct: 1088 GTACE-DLDECAFPGVCPSGV--CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQS 1144
Query: 1316 CKNGGTCAVASNTARGFICKCPAGFE---GATCENDARTCGSLRCLNGGTCISGPRSPTC 1372
GG C NT + C CP GF+ G CE+ G C G C++ S C
Sbjct: 1145 SCLGGEC---KNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFC 1201
Query: 1373 LCLGPFT----GPECQ----FPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLL 1424
LC F G CQ + PC+GG+ +G+ + CLC F
Sbjct: 1202 LCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGS---------FNCLCETGFQ--- 1249
Query: 1425 CHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL-QCNNHACGWDGGDCSLNF 1483
P P E ++ EC ED G+ VC +C N +
Sbjct: 1250 ----------------PSPESGECVDIDEC-EDYGDPVCGTWKCENSPGSY--------- 1283
Query: 1484 NDPWKNCTQSLQCWKYFS-DGHC---DSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDH 1539
C Q + + +G C D N C GF C +G L
Sbjct: 1284 -----RCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGF-CDNTDGSFRCL-------- 1329
Query: 1540 FSDGHCDQGCNSAECEWDGLDCAE 1563
CDQG + WD +D E
Sbjct: 1330 -----CDQGFEISPSGWDCVDVNE 1348
Score = 131 bits (329), Expect = 1e-29
Identities = 185/746 (24%), Positives = 268/746 (35%), Gaps = 161/746 (21%)
Query: 895 CQAGYSGRN---CETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS 951
C GY N C+ DI++C C + + C C PG + + C S
Sbjct: 608 CPQGYKRLNLTHCQ-DINECLTLGLCKDAECVNTRGSYLCTCRPGL---MLDPSRSRCVS 663
Query: 952 DPCRNGAN--CTDCVDSYTCTCPAG---FSGIHCENNTPDCTESSCFNGGTC-VDGINSF 1005
D + C + TCT P I C + S C C + G +F
Sbjct: 664 DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEK---CPLPGTEAF 720
Query: 1006 TCLCPPGFTGSYCQHDVN--------ECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
+CP G +Y D+ E ++P G G GP +
Sbjct: 721 REICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGA----------LPGPAER 770
Query: 1058 NLVH-----WCDSS--PCKNGGKCWQTHTQYRCECPSGWTGLYCD--------------- 1095
+ W ++ P K + Q T P+ TG
Sbjct: 771 QPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVT-HAPAWVTGNATTPPMPEQGIAEIQEEQ 829
Query: 1096 -VPSVSCEVAAQRQGVDVARLCQHG-------GLCVDAGNTHHCRCQAGY----TGSYCE 1143
PS V G+D C G G CV+ + + C C GY + +YC
Sbjct: 830 VTPSTDVLVTLSTPGID---RCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCT 886
Query: 1144 DLVDECSPSPCQNGATCTDYLGGYSCKCVAGY-----HGVNCSEEIDECLSHPCQNGGTC 1198
D +EC PC+ C + +G YSC C GY ++I+EC +GG C
Sbjct: 887 D-DNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQC 945
Query: 1199 LDLPNTYKCSCPRG---TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC-T 1254
+ +Y C C +G + HC+ ++++C R P +G CV+ G Y+C
Sbjct: 946 TNTEGSYHCECDQGYIMVRKGHCQ-DINEC--------RHPGTCPDGRCVNSPGSYTCLA 996
Query: 1255 CPPGFVGERCE-GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKG 1313
C G+ G+ DVNECL+ A G C F C C G+ S GC+
Sbjct: 997 CEEGYRGQSGSCVDVNECLTPGVCAHG--KCTNLEGSFRCSCEQGY---EVTSDEKGCQD 1051
Query: 1314 -KPCKNGGTC--AVASNTARGFICK-CPAGF----EGATCENDARTCGSLRCLNGGTCIS 1365
C + +C + NT F C C G+ +G CE D C G C +
Sbjct: 1052 VDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACE-DLDECAFPGVCPSGVCTN 1110
Query: 1366 GPRSPTCL-CLGPFTG----------PECQFPASSPCLGGNPCYNQGTCEPTSESPFYRC 1414
S +C C G + EC+ P SS CLGG C+ T S Y+C
Sbjct: 1111 TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSS-CLGGE-------CKNTVGS--YQC 1160
Query: 1415 LCPAKF---NGLLCHILDYSFGGGAGRDIPPPLIEEAC-ELPECQEDAGNKVCSLQCNNH 1470
LCP F NG +C ++ G EE C EC G+ C C
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMG------------EEHCAPHGECLNSHGSFFC--LCAPG 1206
Query: 1471 ACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFD-GFDCQRAEGQCN 1529
+GG + ++ C + C GHC + S CL + GF G+C
Sbjct: 1207 FVSAEGGTSCQDVDE----CATTDPC----VGGHCVNTEGSFNCLCETGFQPSPESGECV 1258
Query: 1530 PLYDQYCKDHFSDGHCDQGCNSAECE 1555
+ + C+D + D C + +CE
Sbjct: 1259 DIDE--CED-----YGDPVCGTWKCE 1277
Score = 42.4 bits (98), Expect = 0.006
Identities = 36/115 (31%), Positives = 47/115 (40%), Gaps = 21/115 (18%)
Query: 788 CQTN-INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ 846
C N +N +NP L T D C + + G T + APC P P
Sbjct: 554 CYLNTVNGQCANPLLELTTQEDC-----CGSVGAFWGVT---LCAPCPPRPA-------- 597
Query: 847 SEDYESFSCVCPTGWQGQT---CEVDINECVLSPCRHGASCQNTHGGYRCHCQAG 898
S E+ CP G++ C+ DINEC+ A C NT G Y C C+ G
Sbjct: 598 SPVIENGQLECPQGYKRLNLTHCQ-DINECLTLGLCKDAECVNTRGSYLCTCRPG 651
Score = 41.2 bits (95), Expect = 0.013
Identities = 83/337 (24%), Positives = 109/337 (32%), Gaps = 66/337 (19%)
Query: 35 GKCEAANGTEACVCGGAF----VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACS-- 88
G+C C+C F +C+D + C C+N G C V+ G CS
Sbjct: 1500 GRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLACEN-GEC--VNTEGSFHCFCSPP 1556
Query: 89 ---------CALGFSGP-----------LCLTPLDNACLTNPCRNGGTCDLLTLTEYKCR 128
C S +C + N + P R T T TE C+
Sbjct: 1557 LTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRT----TYTECCCQ 1612
Query: 129 CPPGWSGKSCQQADPCASNPCANGGQCLPFEASYIC--HCPPSFHGPTCRQDVNECGQKP 186
WS + C P +S A EA H P + D++ P
Sbjct: 1613 DGEAWS-QQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGP 1671
Query: 187 GLCRHGGTCHNEVGSYRCVCRATH---TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHEC 243
G +N +G V G + +R P SP Q P+ H
Sbjct: 1672 D----GAPFYNYLGPEDTVPEPAFPNTAGHSADR--TPILESPLQ------PSELQPHYV 1719
Query: 244 ACLP----GFTGQNCEENIDDCPG-NNCKNGGACVDGVNTYNCRCPPEW---TGQYCTED 295
A P GF G EE C N C+NG CV Y C C + D
Sbjct: 1720 ASHPEPPAGFEGLQAEE----CGILNGCENG-RCVRVREGYTCDCFEGFQLDAAHMACVD 1774
Query: 296 VDECQLM--PNACQNGGTCHNTHGGYNCVCVNGWTGE 330
V+EC + P G C NT G Y C C G+ E
Sbjct: 1775 VNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAE 1811
Score = 40.4 bits (93), Expect = 0.023
Identities = 78/367 (21%), Positives = 118/367 (32%), Gaps = 74/367 (20%)
Query: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPC 499
C +G+ CE + D T L G G+ C++ PC
Sbjct: 364 CARGHCANSCE-----------RGDTTTLYSQGGHGHDPKSGFRIYFCQI--------PC 404
Query: 500 LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAK---CLDGP---NTYTCV 553
L+ GRC I +C CP TG C + + P G++ L+ P +T+T
Sbjct: 405 LNGGRC---IGRDECWCPANSTGKFCHLPIPQPDREPPGRGSRPRALLEAPLKQSTFTLP 461
Query: 554 CTEGYTGTHCE-VDIDECDPDPCHY---------GSCKDGVATFTCLCR-----PGYTGH 598
+ + V + P G ++ + + R P GH
Sbjct: 462 LSNQLASVNPSLVKVHIHHPPEASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGH 521
Query: 599 HC--ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCL 656
NI S +P R R L C T C + L
Sbjct: 522 SLWDSNNIPARSGEPPRPLPPAAPRPRGLLGRCYLNTVNGQC-------------ANPLL 568
Query: 657 DKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYH--DPTCL 714
+ +C G G+ + + CA PC NG CP+GY + T
Sbjct: 569 ELTTQEDCC---GSVGAFWGVTL--CA--PCPPRPASPVIENG-QLECPQGYKRLNLTHC 620
Query: 715 SEVNEC-NSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVN--GGTCKDM 771
++NEC C C ++ Y C C P G D + + C S+ ++ G C
Sbjct: 621 QDINECLTLGLCKDAECVNTRGSYLCTCRP---GLMLDPSRSRCVSDKAISMLQGLCYRS 677
Query: 772 TSGYVCT 778
CT
Sbjct: 678 LGPGTCT 684
Score = 38.5 bits (88), Expect = 0.086
Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Query: 876 SPCRHGASCQNTHGGYRCH-CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCL 934
+P R + +N GG C S +C + C P PC N GSC+ C C
Sbjct: 157 TPPRGRLTGRNVCGGQCCPGWTTANSTNHCIKPV--CEP-PCQNRGSCS---RPQLCVCR 210
Query: 935 PGFRGTFCEEDINECASDP 953
GFRG CEE I + DP
Sbjct: 211 SGFRGARCEEVIPDEEFDP 229
Score = 38.1 bits (87), Expect = 0.11
Identities = 28/69 (40%), Positives = 30/69 (43%), Gaps = 10/69 (14%)
Query: 194 TCHNEVGSYRCVCRATHTGPN-CERPYVPCSPSPCQNGGTC-RPTGDVTHECACLPGFTG 251
T N G C T N C +P C P PCQN G+C RP C C GF G
Sbjct: 164 TGRNVCGGQCCPGWTTANSTNHCIKPV--CEP-PCQNRGSCSRP-----QLCVCRSGFRG 215
Query: 252 QNCEENIDD 260
CEE I D
Sbjct: 216 ARCEEVIPD 224
Score = 37.7 bits (86), Expect = 0.15
Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 10/63 (15%)
Query: 741 CDPGWSGTNCDINNNECESN----PCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA 796
C PGW+ N + N C PC N G+C + +C CR GF G C+ I +
Sbjct: 173 CCPGWTTAN---STNHCIKPVCEPPCQNRGSC---SRPQLCVCRSGFRGARCEEVIPDEE 226
Query: 797 SNP 799
+P
Sbjct: 227 FDP 229
Score = 37.4 bits (85), Expect = 0.19
Identities = 35/147 (23%), Positives = 55/147 (37%), Gaps = 20/147 (13%)
Query: 724 PCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECES-NPCVNGGTCKDMT-----SGYVC 777
PC + + +C G+ +N C+ N C+ G CKD Y+C
Sbjct: 591 PCPPRPASPVIENGQLECPQGYKR----LNLTHCQDINECLTLGLCKDAECVNTRGSYLC 646
Query: 778 TCREGFSGPNCQTNINECASNPCLN--QGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP 835
TCR G + + C S+ ++ QG C + C LP + + C+
Sbjct: 647 TCRPGLM---LDPSRSRCVSDKAISMLQGLCYRSLG--PGTCTLPLAQRITKQICC-CSR 700
Query: 836 SPCRNGGECRQS--EDYESFSCVCPTG 860
G EC + E+F +CP G
Sbjct: 701 VGKAWGSECEKCPLPGTEAFREICPAG 727
Score = 35.8 bits (81), Expect = 0.56
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 4/62 (6%)
Query: 513 QCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP 572
QC CP T + + + PC+N C CVC G+ G CE I + +
Sbjct: 172 QC-CPGWTTANSTNHCIKPVCEPPCQNRGSC---SRPQLCVCRSGFRGARCEEVIPDEEF 227
Query: 573 DP 574
DP
Sbjct: 228 DP 229
Score = 35.4 bits (80), Expect = 0.73
Identities = 25/77 (32%), Positives = 30/77 (38%), Gaps = 13/77 (16%)
Query: 133 WSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFH--GPTCRQDVNECGQKPGLCR 190
W C P ++P GQ CP + T QD+NEC GLC+
Sbjct: 584 WGVTLCAPCPPRPASPVIENGQL---------ECPQGYKRLNLTHCQDINEC-LTLGLCK 633
Query: 191 HGGTCHNEVGSYRCVCR 207
C N GSY C CR
Sbjct: 634 DA-ECVNTRGSYLCTCR 649
Score = 35.0 bits (79), Expect = 0.95
Identities = 70/303 (23%), Positives = 99/303 (32%), Gaps = 69/303 (22%)
Query: 1119 GGLC----VDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAG 1174
GG C A +T+HC + C P PCQN +C+ C C +G
Sbjct: 170 GGQCCPGWTTANSTNHC-------------IKPVCEP-PCQNRGSCSR---PQLCVCRSG 212
Query: 1175 YHGVNCSEEIDECLSHPCQNGGTCLDL-----PNTYKCSCPRGTQGVHCEINVDDCNP-P 1228
+ G C E I + P QN PN + S + P P
Sbjct: 213 FRGARCEEVIPDEEFDP-QNSRLAPRRWAERSPNLRRSSAAGEGTLARAQPPAPQSPPAP 271
Query: 1229 VDP-------------------VSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVN 1269
P +SR+ + T Q+ S PPG E+ +G
Sbjct: 272 QSPPAGTLSGLSQTHPSQQHVGLSRTVRLHPTATASSQLS--SNALPPGPGLEQRDGTQQ 329
Query: 1270 EC-LSNPCDARGTQNCVQRVNDFHCECRAGHTGRRC-ESVINGCKGKPCKNGGTCAVASN 1327
L +P G N +++ + + T C ++ G C+ G T + S
Sbjct: 330 AVPLEHPSSPWGL-NLTEKIK----KIKIVFTPTICKQTCARGHCANSCERGDTTTLYSQ 384
Query: 1328 TARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPA 1387
G K +GF C+ + CLNGG CI C C TG C P
Sbjct: 385 GGHGHDPK--SGFRIYFCQ--------IPCLNGGRCIG---RDECWCPANSTGKFCHLPI 431
Query: 1388 SSP 1390
P
Sbjct: 432 PQP 434
Score = 35.0 bits (79), Expect = 0.95
Identities = 35/150 (23%), Positives = 52/150 (34%), Gaps = 22/150 (14%)
Query: 911 CRPNPCHNGGSCTDGINTAFCDCLPGFRG---TFCEEDINECASDPCRNGANCTDCVDSY 967
C P P + I +C G++ T C+ DINEC + A C + SY
Sbjct: 592 CPPRPA------SPVIENGQLECPQGYKRLNLTHCQ-DINECLTLGLCKDAECVNTRGSY 644
Query: 968 TCTCPAGFSGIHCENNTPDCTESSCFN--GGTCVDGINSFTCLCPPGFTGSYCQHDVNEC 1025
CTC G+ + + C + G C + TC P + C
Sbjct: 645 LCTCR---PGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLP---LAQRITKQICCC 698
Query: 1026 DSQPCLHGGTCQ----DGCGSYRCTCPQGY 1051
G C+ G ++R CP G+
Sbjct: 699 SRVGKAWGSECEKCPLPGTEAFREICPAGH 728
Score = 35.0 bits (79), Expect = 0.95
Identities = 30/89 (33%), Positives = 34/89 (38%), Gaps = 19/89 (21%)
Query: 1337 PAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNP 1396
PAGFEG E CG L G C+ TC C F G + A C+ N
Sbjct: 1726 PAGFEGLQAEE----CGILNGCENGRCVRVREGYTCDC---FEGFQLD-AAHMACVDVNE 1777
Query: 1397 CYN---------QGTCEPTSESPFYRCLC 1416
C + G CE T S YRC C
Sbjct: 1778 CDDLNGPAVLCVHGYCENTEGS--YRCHC 1804
Score = 34.3 bits (77), Expect = 1.6
Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 4/64 (6%)
Query: 275 GVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSE 334
G N +C P WT T + P CQN G+C CVC +G+ G C E
Sbjct: 165 GRNVCGGQCCPGWTTANSTNHCIKPVCEP-PCQNRGSCSRPQ---LCVCRSGFRGARCEE 220
Query: 335 NIDD 338
I D
Sbjct: 221 VIPD 224
Score = 34.3 bits (77), Expect = 1.6
Identities = 26/98 (26%), Positives = 35/98 (35%), Gaps = 19/98 (19%)
Query: 937 FRGTFCEEDINECASDPCRNGANCTDCVDSYTC-----TCPAGFSGIHCENNTPDCTESS 991
F T C++ CA C N D Y+ +GF C+
Sbjct: 355 FTPTICKQT---CARGHCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQ--------IP 403
Query: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQP 1029
C NGG C I C CP TG +C + + D +P
Sbjct: 404 CLNGGRC---IGRDECWCPANSTGKFCHLPIPQPDREP 438
Score = 33.9 bits (76), Expect = 2.1
Identities = 19/63 (30%), Positives = 24/63 (38%), Gaps = 4/63 (6%)
Query: 925 GINTAFCDCLPGFR-GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN 983
G N C PG+ I PC+N +C+ C C +GF G CE
Sbjct: 165 GRNVCGGQCCPGWTTANSTNHCIKPVCEPPCQNRGSCSR---PQLCVCRSGFRGARCEEV 221
Query: 984 TPD 986
PD
Sbjct: 222 IPD 224
Score = 33.9 bits (76), Expect = 2.1
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 8/68 (11%)
Query: 1034 GTCQDGC--GSYRCTCPQGYTG--PNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1089
G C + C G QG G P +++C PC NGG+C C CP+
Sbjct: 367 GHCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQI-PCLNGGRCIGRD---ECWCPANS 422
Query: 1090 TGLYCDVP 1097
TG +C +P
Sbjct: 423 TGKFCHLP 430
Score = 33.1 bits (74), Expect = 3.6
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 7/75 (9%)
Query: 1151 PSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE-IDECLSHPCQNGGTCLDLPNTYKCSC 1209
P+P + T + GG +C G+ N + I PCQN G+C C C
Sbjct: 156 PTPPRGRLTGRNVCGG---QCCPGWTTANSTNHCIKPVCEPPCQNRGSC---SRPQLCVC 209
Query: 1210 PRGTQGVHCEINVDD 1224
G +G CE + D
Sbjct: 210 RSGFRGARCEEVIPD 224
Score = 32.7 bits (73), Expect = 4.7
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 10/66 (15%)
Query: 591 CRPGYTG----HHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCA 646
C PG+T +HC I PC++ G+C LC C G G CE + D
Sbjct: 173 CCPGWTTANSTNHC---IKPVCEPPCQNRGSCS---RPQLCVCRSGFRGARCEEVIPDEE 226
Query: 647 SSPCDS 652
P +S
Sbjct: 227 FDPQNS 232
Score = 32.3 bits (72), Expect = 6.1
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 6/59 (10%)
Query: 809 DVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE 867
+V G +C +T + C P PC+N G C + + CVC +G++G CE
Sbjct: 167 NVCGGQCCPGWTTANSTNHCIKPVCEP-PCQNRGSCSRPQ-----LCVCRSGFRGARCE 219
Score = 32.0 bits (71), Expect = 8.0
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 14/78 (17%)
Query: 1154 CQNGATCTDYL-GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG 1212
C+ G T T Y GG+ +G+ C PC NGG C+ +C CP
Sbjct: 373 CERGDTTTLYSQGGHGHDPKSGFRIYFCQI--------PCLNGGRCI---GRDECWCPAN 421
Query: 1213 TQGVHCEINV--DDCNPP 1228
+ G C + + D PP
Sbjct: 422 STGKFCHLPIPQPDREPP 439
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 270 bits (691), Expect = 1e-71
Identities = 255/867 (29%), Positives = 330/867 (38%), Gaps = 256/867 (29%)
Query: 478 CMPGY--EGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVD----- 530
C PG+ G C CA C+H GRC I C+C G+ G C D
Sbjct: 94 CCPGFYESGEMC---VPHCADK-CVH-GRC---IAPNTCQCEPGWGGTNCSSACDGDHWG 145
Query: 531 -ECAST-PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP----DPCHYG-SCKDG 583
C S CKNGA C P T C C G+ G CE D C+ + CH C++G
Sbjct: 146 PHCTSRCQCKNGALC--NPITGACHCAAGFRGWRCE---DRCEQGTYGNDCHQRCQCQNG 200
Query: 584 VA----TFTCLCRPGYTGHHCET------NINECSSQ-PCRHGGTCQDRDNAYLCF---- 628
T C C PGYTG CE + +C + PC++GG C C
Sbjct: 201 ATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWM 260
Query: 629 -------CLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDE 681
C +G G NC +C C +G D G +C C PGYTG C DE
Sbjct: 261 GTVCGQPCPEGRFGKNCS---QECQ---CHNGGTCDAATG-QCHCSPGYTGERCQ---DE 310
Query: 682 CAGNP----------CHNGGTC---------EDGINGFTCR---CPEGYHDPTC------ 713
C C NGG C E G G C CPEG + C
Sbjct: 311 CPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPC 370
Query: 714 -LSEVNECN--SNPCVHGACRDSLNGYKCD--CDPGWSGTNCDINNNECESNPCVNGGTC 768
L + C+ S C AC+ +G C+ C PG+ G C + C NG C
Sbjct: 371 HLENTHSCHPMSGEC---ACKPGWSGLYCNETCSPGFYGEACQ------QICSCQNGADC 421
Query: 769 KDMTSGYVCTCREGFSGPNCQT-------NINECASNPCLNQGTCIDDVAGYKCNCLLPY 821
+T CTC GF G +C T IN + C N C V G C C +
Sbjct: 422 DSVTGK--CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC-SPVDG-SCTCKAGW 477
Query: 822 TGATCEVVLAPCA-------PSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVD----- 869
G C + C NGG C + +C C GW+G+ CE+
Sbjct: 478 HGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDG----TCTCAPGWRGEKCELPCQDGT 533
Query: 870 --INECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP-------CHNGG 920
+N C H C T G C C G+SG +C++ + R P C NG
Sbjct: 534 YGLNCAERCDCSHADGCHPTTG--HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGA 591
Query: 921 SCT--DGINTAFCDCLPGFRGTFCE-------------EDINEC--ASDPCRNGANCTDC 963
SC+ DGI C+C PGFRGT C+ + +C +S PC + DC
Sbjct: 592 SCSPDDGI----CECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDC 647
Query: 964 VDSYT---C--TCPAGFSGIHCENNTPDCTESSCFNGGTC--VDGINSFTCLCPPGFTGS 1016
+ +T C CP+G G +C CT C N GTC +D +C C PG+ GS
Sbjct: 648 LPGFTGALCNEVCPSGRFGKNCAG---ICT---CTNNGTCNPIDR----SCQCYPGWIGS 697
Query: 1017 YCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQ 1076
C SQP CP + GPNC +H C+ C NG C
Sbjct: 698 DC--------SQP-----------------CPPAHWGPNC---IHTCN---CHNGAFC-- 724
Query: 1077 THTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH----CR 1132
+ C+C GWTGLYC + C + G D A +CQ C + + H C
Sbjct: 725 SAYDGECKCTPGWTGLYC---TQRCPLGF--YGKDCALICQ----CQNGADCDHISGQCT 775
Query: 1133 CQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPC 1192
C+ G+ G +CE KC +G +G C + D C
Sbjct: 776 CRTGFMGRHCEQ-------------------------KCPSGTYGYGCRQICD------C 804
Query: 1193 QNGGTCLDLPNTYKCSCPRGTQGVHCE 1219
N TC + T C C G +G C+
Sbjct: 805 LNNSTCDHITGT--CYCSPGWKGARCD 829
Score = 259 bits (662), Expect = 2e-68
Identities = 248/874 (28%), Positives = 316/874 (36%), Gaps = 273/874 (31%)
Query: 89 CALGF--SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA----- 141
C GF SG +C+ + C+ C TC +C PGW G +C A
Sbjct: 94 CCPGFYESGEMCVPHCADKCVHGRCIAPNTC----------QCEPGWGGTNCSSACDGDH 143
Query: 142 --DPCASN-PCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNE 198
C S C NG C P + CHC F G C + C Q +G CH
Sbjct: 144 WGPHCTSRCQCKNGALCNPITGA--CHCAAGFRGWRCE---DRCEQGT----YGNDCHQ- 193
Query: 199 VGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
RC CQNG TC VT EC C PG+TG CE
Sbjct: 194 ----RC---------------------QCQNGATC---DHVTGECRCPPGYTGAFCE--- 222
Query: 259 DDCPGNN----------CKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNA--- 305
D CP C+NGG C T C CP W G C + E + N
Sbjct: 223 DLCPPGKHGPQCEQRCPCQNGGVCHH--VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQE 280
Query: 306 --CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC----------ASAACFHGATCHDR 353
C NGGTC G C C G+TGE C D+C + C +G C+
Sbjct: 281 CQCHNGGTCDAATG--QCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHV 335
Query: 354 VASFYCE------------CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAIC--- 398
+ CE CP G G+ C + C PC+ + +P++G+ C
Sbjct: 336 SGACLCEAGFAGERCEARLCPEGLYGIKC--DKRC---PCHLENTHSCHPMSGECACKPG 390
Query: 399 --------TCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE 450
TC G+ G AC Q CS C++ C + G +C C G+ G C
Sbjct: 391 WSGLYCNETCSPGFYGEACQQ---ICS-----CQNGADCDSVTG--KCTCAPGFKGIDCS 440
Query: 451 -------IDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNG 503
+N C+NDA C G C C G+ GV C +
Sbjct: 441 TPCPLGTYGINCSSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCSI-------------- 484
Query: 504 RCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKC--LDGPNTYTCVCTEGYTGT 561
CP+G G C + C NG C LDG TC C G+ G
Sbjct: 485 -----------RCPSGTWGFGCN------LTCQCLNGGACNTLDG----TCTCAPGWRGE 523
Query: 562 HCEVD----------IDECD---PDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECS 608
CE+ + CD D CH T C C PG++G HC++ E
Sbjct: 524 KCELPCQDGTYGLNCAERCDCSHADGCH-------PTTGHCRCLPGWSGVHCDSVCAEGR 576
Query: 609 SQP-------CRHGGTCQDRDNAYLC-----------FCLKGTTGPNCEINLDDC--ASS 648
P C++G +C D C C G G C C +S
Sbjct: 577 WGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSG 636
Query: 649 PCDSGTCLDKIDGYECACEPGYTGSMCNINI------DECAG-NPCHNGGTCE------- 694
PC T L C C PG+TG++CN CAG C N GTC
Sbjct: 637 PCHHITGL-------CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQ 689
Query: 695 --DGINGFTCR--CPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNC 750
G G C CP + P C ++ CN C +GA + +G +C C PGW+G C
Sbjct: 690 CYPGWIGSDCSQPCPPAHWGPNC---IHTCN---CHNGAFCSAYDG-ECKCTPGWTGLYC 742
Query: 751 ------DINNNECE-SNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN----- 798
+C C NG C D SG CTCR GF G +C+ +C S
Sbjct: 743 TQRCPLGFYGKDCALICQCQNGADC-DHISGQ-CTCRTGFMGRHCE---QKCPSGTYGYG 797
Query: 799 -----PCLNQGTCIDDVAGYKCNCLLPYTGATCE 827
CLN TC D + G C C + GA C+
Sbjct: 798 CRQICDCLNNSTC-DHITG-TCYCSPGWKGARCD 829
Score = 256 bits (653), Expect = 3e-67
Identities = 235/827 (28%), Positives = 311/827 (37%), Gaps = 212/827 (25%)
Query: 23 RCSQPGETCLNGGKCEAANGTEAC--VCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRR 80
RC P TC +CE G C C G GP C CKN C+ +
Sbjct: 117 RCIAPN-TC----QCEPGWGGTNCSSACDGDHWGPHCTS-----RCQCKNGALCNPITG- 165
Query: 81 GVADYACSCALGFSGPLCLTPLDNACLTN------PCRNGGTCDLLTLTEYKCRCPPGWS 134
AC CA GF G C + N C+NG TCD +T +CRCPPG++
Sbjct: 166 -----ACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVT---GECRCPPGYT 217
Query: 135 GKSCQQADPCASN--------PCANGGQCLPFEASYICHCPPSFHGPTCRQDVNE----- 181
G C+ P + PC NGG C + C CP + G C Q E
Sbjct: 218 GAFCEDLCPPGKHGPQCEQRCPCQNGGVC--HHVTGECSCPSGWMGTVCGQPCPEGRFGK 275
Query: 182 -CGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPY------VPCSPS-PCQNGGTC 233
C Q+ C +GGTC G +C C +TG C+ V C+ + C NGG C
Sbjct: 276 NCSQE-CQCHNGGTCDAATG--QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKC 332
Query: 234 RPTGDVTHECACLPGFTGQNCEENIDDCP----GNNCKNGGACVDGVNTYNCR------- 282
V+ C C GF G+ CE + CP G C C NT++C
Sbjct: 333 Y---HVSGACLCEAGFAGERCEARL--CPEGLYGIKCDKRCPC-HLENTHSCHPMSGECA 386
Query: 283 CPPEWTGQYCTEDV------DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSE-- 334
C P W+G YC E + CQ + +CQNG C + G C C G+ G DCS
Sbjct: 387 CKPGWSGLYCNETCSPGFYGEACQQI-CSCQNGADCDSVTG--KCTCAPGFKGIDCSTPC 443
Query: 335 -----NIDDCASAACFHGATCHDRVASFYCE-----------CPHGRTGLLCHLNDACIS 378
I+ + C + A C S C+ CP G G C+L C++
Sbjct: 444 PLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLN 503
Query: 379 NPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTL 433
G C+T ++G CTC G+ G C + + G N C HA C T
Sbjct: 504 -----GGACNT--LDG--TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTT 554
Query: 434 GSFECQCLQGYTGPRCEIDVNECVSNP-------CQNDATCLDQIGEFQC---------- 476
G C+CL G++G C+ E P C+N A+C G +C
Sbjct: 555 G--HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQ 612
Query: 477 -ICMPGYEGVHCEVNTDEC--ASSPCLHNGRCLDKINEFQCECPTGFTGHLC-------Q 526
IC PG+ G C +C +S PC H C+C GFTG LC +
Sbjct: 613 RICSPGFYGHRCSQTCPQCVHSSGPCHHITGL--------CDCLPGFTGALCNEVCPSGR 664
Query: 527 YDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG-SCKDGVA 585
+ + C N C P +C C G+ G+ C C P H+G +C
Sbjct: 665 FGKNCAGICTCTNNGTC--NPIDRSCQCYPGWIGSDCS---QPC--PPAHWGPNC----- 712
Query: 586 TFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDC 645
TC C + G C EC P G C R C G G +C +
Sbjct: 713 IHTCNC---HNGAFCSAYDGECKCTPGWTGLYCTQR-------CPLGFYGKDCAL----- 757
Query: 646 ASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCP 705
C +G D I G +C C G+ G C C G G+ CR
Sbjct: 758 -ICQCQNGADCDHISG-QCTCRTGFMGRHCE--------------QKCPSGTYGYGCR-- 799
Query: 706 EGYHDPTCLSEVNEC-NSNPCVHGACRDSLNGYKCDCDPGWSGTNCD 751
++ +C N++ C D + G C C PGW G CD
Sbjct: 800 ----------QICDCLNNSTC------DHITG-TCYCSPGWKGARCD 829
Score = 246 bits (627), Expect = 3e-64
Identities = 237/811 (29%), Positives = 295/811 (36%), Gaps = 216/811 (26%)
Query: 850 YESFSCVCPTGWQ-GQTCEVDINECVLSPCRHGAS-CQNTHGGYRCHCQAGYSGRNCETD 907
Y S CP ++ G+ C + C C HG NT C C+ G+ G NC +
Sbjct: 88 YRRKSQCCPGFYESGEMC---VPHCA-DKCVHGRCIAPNT-----CQCEPGWGGTNCSSA 138
Query: 908 IDDCRPNP-------CHNGGSCTDGINTAFCDCLPGFRGTFCEEDI------NECASD-P 953
D P C NG C T C C GFRG CE+ N+C
Sbjct: 139 CDGDHWGPHCTSRCQCKNGALCNP--ITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQ 196
Query: 954 CRNGANCTDCVDSYTCTCPAGFSGIHCEN------NTPDCTESS-CFNGGTC--VDGINS 1004
C+NGA C C CP G++G CE+ + P C + C NGG C V G
Sbjct: 197 CQNGATCDHVTGE--CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTG--- 251
Query: 1005 FTCLCPPGFTGSYCQHDVNE------CDSQ-PCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
C CP G+ G+ C E C + C +GGTC G +C C GYTG CQ
Sbjct: 252 -ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATG--QCHCSPGYTGERCQ 308
Query: 1058 NL-------VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGV 1110
+ V ++ C NGGKC+ H C C +G+ G C+
Sbjct: 309 DECPVGTYGVLCAETCQCVNGGKCY--HVSGACLCEAGFAGERCE--------------- 351
Query: 1111 DVARLCQHG--GLCVDAG------NTHHCR-------CQAGYTGSYCEDLVDECSPS--- 1152
ARLC G G+ D NTH C C+ G++G YC + CSP
Sbjct: 352 --ARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNET---CSPGFYG 406
Query: 1153 -------PCQNGATCTDYLGGYSCKCVAGYHGVNCSEEID------ECLSH-PCQNGGTC 1198
CQNGA C G C C G+ G++CS C S C+N C
Sbjct: 407 EACQQICSCQNGADCDSVTG--KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC 464
Query: 1199 LDLPNTYKCSCPRGTQGVHCEINVDD------CNPPVDPVSRSPKCFNNGTCVDQVGGYS 1252
+ + C+C G GV C I CN + +C N G C G +
Sbjct: 465 SPVDGS--CTCKAGWHGVDCSIRCPSGTWGFGCN-------LTCQCLNGGACNTLDG--T 513
Query: 1253 CTCPPGFVGERCE-----GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESV 1307
CTC PG+ GE+CE G + CD C HC C G +G C+SV
Sbjct: 514 CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWSGVHCDSV 571
Query: 1308 INGCKGKP-------CKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCG----SLR 1356
+ P CKNG +C+ IC+C GF G TC+ R C R
Sbjct: 572 CAEGRWGPNCSLPCYCKNGASCSPDDG-----ICECAPGFRGTTCQ---RICSPGFYGHR 623
Query: 1357 CLNGGTC-----ISGPR---SPTCLCLGPFTGPECQFPASSPCLGGN-----PCYNQGTC 1403
C TC SGP + C CL FTG C S G N C N GTC
Sbjct: 624 CSQ--TCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTC 681
Query: 1404 EPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVC 1463
P S C C + G G D P C C
Sbjct: 682 NPIDRS----CQC---------------YPGWIGSDCSQP----------CPPAHWGPNC 712
Query: 1464 SLQCNNH---ACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFD 1520
CN H C G+C CTQ Y D QC +G D
Sbjct: 713 IHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQ------NGAD 766
Query: 1521 CQRAEGQCNPLYDQYCKDHFSDGHCDQGCNS 1551
C GQC C+ F HC+Q C S
Sbjct: 767 CDHISGQCT------CRTGFMGRHCEQKCPS 791
Score = 238 bits (607), Expect = 6e-62
Identities = 227/764 (29%), Positives = 299/764 (39%), Gaps = 183/764 (23%)
Query: 722 SNPCVHGACRDSLNGYKCDCDPGWSGTNC------DINNNECESN-PCVNGGTCKDMTSG 774
++ CVHG C + C C+PGW GTNC D C S C NG C +T
Sbjct: 110 ADKCVHGRC---IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGA 166
Query: 775 YVCTCREGFSGPNCQ------TNINECASN-PCLNQGTCIDDVAGYKCNCLLPYTGATCE 827
C C GF G C+ T N+C C N TC D V G +C C YTGA CE
Sbjct: 167 --CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC-DHVTG-ECRCPPGYTGAFCE 222
Query: 828 VVLAP------CAPS-PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP--- 877
+ P C PC+NGG C + + C CP+GW G C E
Sbjct: 223 DLCPPGKHGPQCEQRCPCQNGGVCH----HVTGECSCPSGWMGTVCGQPCPEGRFGKNCS 278
Query: 878 ----CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP----------CHNGGSCT 923
C +G +C G +CHC GY+G C+ D+C C NGG C
Sbjct: 279 QECQCHNGGTCDAATG--QCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCY 333
Query: 924 DGINTAFCDCLPGFRGTFCE-----EDINECASD---PCR--NGANCTDCVDSYTCTCPA 973
C+ GF G CE E + D PC N +C S C C
Sbjct: 334 HVSGACLCEA--GFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPM--SGECACKP 389
Query: 974 GFSGIHC-ENNTPD-----CTE-SSCFNGGTCVDGINSFTCLCPPGFTGSYCQ------- 1019
G+SG++C E +P C + SC NG C D + C C PGF G C
Sbjct: 390 GWSGLYCNETCSPGFYGEACQQICSCQNGADC-DSVTG-KCTCAPGFKGIDCSTPCPLGT 447
Query: 1020 HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVH---W---CD-SSPCKNGG 1072
+ +N C + C GS CTC G+ G +C W C+ + C NGG
Sbjct: 448 YGINCSSRCGCKNDAVCSPVDGS--CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGG 505
Query: 1073 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH--- 1129
C C C GW G C++P C+ G++ A C C A H
Sbjct: 506 AC--NTLDGTCTCAPGWRGEKCELP---CQDGTY--GLNCAERCD----CSHADGCHPTT 554
Query: 1130 -HCRCQAGYTGSYCEDLVDE------CS-PSPCQNGATCTDYLG---------GYSCK-- 1170
HCRC G++G +C+ + E CS P C+NGA+C+ G G +C+
Sbjct: 555 GHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRI 614
Query: 1171 CVAGYHGVNCSEEIDECL--SHPCQN-GGTCLDLPNTYK--CS--CPRGTQGVHCE---- 1219
C G++G CS+ +C+ S PC + G C LP C+ CP G G +C
Sbjct: 615 CSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICT 674
Query: 1220 -INVDDCNP------------------PVDPVSRSPKCFNNGTCVDQVGGY------SCT 1254
N CNP P P P C + TC G + C
Sbjct: 675 CTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIH--TCNCHNGAFCSAYDGECK 732
Query: 1255 CPPGFVG----ERCE-GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI- 1308
C PG+ G +RC G + + C + +C C CR G GR CE
Sbjct: 733 CTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQ--CTCRTGFMGRHCEQKCP 790
Query: 1309 NGCKGKPCK------NGGTCAVASNTARGFICKCPAGFEGATCE 1346
+G G C+ N TC + T C C G++GA C+
Sbjct: 791 SGTYGYGCRQICDCLNNSTCDHITGT-----CYCSPGWKGARCD 829
Score = 197 bits (502), Expect = 8e-50
Identities = 191/633 (30%), Positives = 243/633 (38%), Gaps = 166/633 (26%)
Query: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNP-------CLST-PCKNAG 72
G CSQ + C NGG C+AA G C C + G RCQD P C T C N G
Sbjct: 274 GKNCSQECQ-CHNGGTCDAATGQ--CHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGG 330
Query: 73 TCHVVDRRGVADYACSCALGFSGPLCLTPL----------DNACLTNPC--RNGGTCDLL 120
C+ V AC C GF+G C L D C PC N +C +
Sbjct: 331 KCYHVSG------ACLCEAGFAGERCEARLCPEGLYGIKCDKRC---PCHLENTHSCHPM 381
Query: 121 TLTEYKCRCPPGWSGKSCQQ-------ADPCAS-NPCANGGQCLPFEASYICHCPPSFHG 172
+ +C C PGWSG C + + C C NG C C C P F G
Sbjct: 382 S---GECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGK--CTCAPGFKG 436
Query: 173 PTCRQDVN------ECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPS- 225
C C + G C++ C GS C C+A G +C + C PS
Sbjct: 437 IDCSTPCPLGTYGINCSSRCG-CKNDAVCSPVDGS--CTCKAGWHGVDCS---IRC-PSG 489
Query: 226 ----------PCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDD-CPGNNCKNGGAC-- 272
C NGG C T D T C C PG+ G+ CE D G NC C
Sbjct: 490 TWGFGCNLTCQCLNGGACN-TLDGT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSH 546
Query: 273 VDGVN--TYNCRCPPEWTGQYCTEDVDECQLMPNA-----CQNGGTCHNTHGGYNC---- 321
DG + T +CRC P W+G +C E + PN C+NG +C G C
Sbjct: 547 ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGF 606
Query: 322 -------VCVNGWTGEDCSENIDDC--ASAACFHGATCHDRVASFYCECPHGRTGLLCHL 372
+C G+ G CS+ C +S C H + C+C G TG LC
Sbjct: 607 RGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHH--------ITGLCDCLPGFTGALC-- 656
Query: 373 NDACISNP--------CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCE 424
N+ C S C +N NP++ C C G+ G CSQ G N C
Sbjct: 657 NEVCPSGRFGKNCAGICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWGPN-CI 713
Query: 425 HAGKCINTLGSF------ECQCLQGYTG----PRCEIDV--NEC-VSNPCQNDATCLDQI 471
H C N G+F EC+C G+TG RC + +C + CQN A C D I
Sbjct: 714 HTCNCHN--GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC-DHI 770
Query: 472 GEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDE 531
QC C G+ G HCE +CP+G G+ C+ D
Sbjct: 771 SG-QCTCRTGFMGRHCEQ-------------------------KCPSGTYGYGCRQICD- 803
Query: 532 CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
C N + C T TC C+ G+ G C+
Sbjct: 804 -----CLNNSTC--DHITGTCYCSPGWKGARCD 829
Score = 55.5 bits (132), Expect = 7e-07
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 22/133 (16%)
Query: 21 GPRCSQPGETCLNGGKCEAANGTEACVCG--GAFVGPRCQ----DPNPCLSTPCKNAGTC 74
GP C C NG C A +G C G G + RC + L C+N C
Sbjct: 709 GPNCIHTCN-CHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC 767
Query: 75 HVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCR------NGGTCDLLTLTEYKCR 128
+ + C+C GF G C + CR N TCD +T T C
Sbjct: 768 DHISGQ------CTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGT---CY 818
Query: 129 CPPGWSGKSCQQA 141
C PGW G C QA
Sbjct: 819 CSPGWKGARCDQA 831
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 270 bits (689), Expect = 2e-71
Identities = 369/1382 (26%), Positives = 508/1382 (36%), Gaps = 312/1382 (22%)
Query: 8 LLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRC-QDPNPCLST 66
LL ++LL LA GP QPG L G + C G RC P T
Sbjct: 7 LLWVSLLVLLAQLGP---QPGLGRL-GERLRVRFTPVVC-------GLRCVHGPTGSRCT 55
Query: 67 PCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYK 126
P VD G A GF LC PL C NGG C + +
Sbjct: 56 PTCAPRNATSVDS-GAPGGAAPGGPGFRAFLC--PLI-------CHNGGVC----VKPDR 101
Query: 127 CRCPPGWSGKSCQQ----ADPCA-----------SNPCAN------GGQCL-------PF 158
C CPP ++GK CQ A P A + P AN G + P
Sbjct: 102 CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQ 161
Query: 159 EASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRC-------------V 205
EAS + H GP D + R V +
Sbjct: 162 EASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGY 221
Query: 206 CRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV--THECACLPGFTGQNCEENIDDCPG 263
C G C P P CR G H+C Q C E + +
Sbjct: 222 CFRELRGGECASPL----PGLRTQEVCCRGAGLAWGVHDC--------QLCSERLGNSER 269
Query: 264 NNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC 323
+ +G C G N C EDVDEC CQ+G C NT GGY CVC
Sbjct: 270 VSAPDG-PCPTGFERVNGSC----------EDVDECAT-GGRCQHG-ECANTRGGYTCVC 316
Query: 324 VNGW----TGEDC-SENIDDCASAACFHGATCHDRVASFYCECPHGR--TGLLCHLNDAC 376
+G+ + C S+++ A CF + C P R T +C C
Sbjct: 317 PDGFLLDSSRSSCISQHVISEAKGPCFR------VLRDGGCSLPILRNITKQIC----CC 366
Query: 377 ISNPCNEGSNCDTNPVNG----KAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINT 432
G C P G + IC GY A + LG P + T
Sbjct: 367 SRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRT 426
Query: 433 LGS-----------------------------FECQCLQGYTGPRCEIDVNECVSNPCQN 463
L + + +TGP EI + S CQ
Sbjct: 427 LPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGP--EIPESGPSSGMCQR 484
Query: 464 D------ATCLDQIGEFQCICMPGY----EGVHCEVNTDEC--ASSPCLHNGRCLDKINE 511
+ C+ + + C C G+ +G C ++ DEC PC GRC +
Sbjct: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGS 542
Query: 512 FQCECPTGF----TGHLCQYDVDEC--ASTPCKNGAKCLDGPNTYTCVCTEGYT----GT 561
F+C C GF C DVDEC PC G +C + P ++ CVC GY G
Sbjct: 543 FRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGA 600
Query: 562 HCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHG-GTC 618
C+ D+DEC P C G+CK+ +F C+C G+ G CE +++EC+ +P G G C
Sbjct: 601 SCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC 659
Query: 619 QDRDNAYLCFCLKG--TTGPN--CEINLDDCASS--PCDSGTCLDKIDGYECAC----EP 668
+ ++ C C G + GP C+ ++D+CA S PC G C + ++C C +P
Sbjct: 660 DNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 718
Query: 669 GYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR-CPEGYH-DPTCLSEVNECNSN--P 724
GS C ++DEC + G C + F CR CP G+H ++V+EC+S P
Sbjct: 719 NTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPP 777
Query: 725 C-VHGACRDSLNGYKCDCDPGW------SGTNCDINNNEC-ESNPCVNGGTCKDMTSGYV 776
C HG C ++ ++C C PG+ G D+ NEC E + C G C + +
Sbjct: 778 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV--NECLEGDFCFPHGECLNTDGSFA 835
Query: 777 CTCREGF----SGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP 832
CTC G+ G +C +++EC+ G C + ++C C G LA
Sbjct: 836 CTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECIC---PPGHRAGPDLAS 891
Query: 833 CAP-SPCRNGGEC-----RQSEDYESFSCV--CPTGWQG---QTCEVDINEC-VLSPCRH 880
C CR G R S+ CV C G+ TC+ D++EC P
Sbjct: 892 CLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC 950
Query: 881 GAS-CQNTHGGYRC--HCQAGYS---GRNCETDIDDCRPNP-CHNGGSCTDGINTAFCDC 933
GA C+NT G YRC C GY G C+ D+D+CR C C + + C C
Sbjct: 951 GAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLC 1009
Query: 934 LPGFRGT----FCEEDINECAS-DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCT 988
G+ G C D+NEC + A C + S+ C CP N+P+
Sbjct: 1010 DQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP----------NSPEEF 1058
Query: 989 ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL-----------HGGTCQ 1037
+ G CV PP + + + P L T +
Sbjct: 1059 DPMT---GRCV----------PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPR 1105
Query: 1038 DG-CGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDV 1096
G GS R C P+ CD+ +N WQ + C GW G C +
Sbjct: 1106 QGPVGSGRRECYFDTAAPDA------CDNILARN--VTWQ---ECCCTVGEGW-GSGCRI 1153
Query: 1097 PSVSCEVAAQRQGVDVARLCQHG-GLCVDAGNTHHCRCQAGYTGSYCEDLVDECS---PS 1152
A+ Q LC HG G +G+ R VDEC
Sbjct: 1154 QQCPGTETAEYQS-----LCPHGRGYLAPSGDLSLRRD------------VDECQLFRDQ 1196
Query: 1153 PCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDECL-SHPCQNGGTCLDLPNTYKC 1207
C++G C + GYSC C GY+ + C + DEC P GG C++ +Y C
Sbjct: 1197 VCKSG-VCVNTAPGYSCYCSNGYYYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHC 1254
Query: 1208 SC 1209
+C
Sbjct: 1255 TC 1256
Score = 259 bits (661), Expect = 3e-68
Identities = 240/860 (27%), Positives = 336/860 (39%), Gaps = 161/860 (18%)
Query: 131 PGWSGKSCQQADP----CASNPCANG-GQCLPFEASYICHCPPSFH----GPTCRQDVNE 181
P W+G ++ P C NP G G+C+ + Y C C F G C DV+E
Sbjct: 465 PAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCI-DVDE 523
Query: 182 CGQKPGLCRHGGTCHNEVGSYRCVCR-ATHTGPN---------CERPYVPCSPSPCQNGG 231
C + P C G C N GS+RCVC GP C R PC C+N
Sbjct: 524 CRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP 582
Query: 232 TCRPTGDVTHECACLPGFT----GQNCEENIDDCPGNNCKNG-GACVDGVNTYNCRCPPE 286
+ C C G+ G +C++ +D+C + G GAC + ++ C CP
Sbjct: 583 G-------SFLCVCPAGYQAAPHGASCQD-VDECTQSPGLCGRGACKNLPGSFRCVCPAG 634
Query: 287 WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT----GEDCSENIDDCASA 342
+ G C EDVDEC P C G C NT G ++C C G+ G C +++D+CA +
Sbjct: 635 FRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARS 692
Query: 343 A--CFHGATCHDRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKA 396
C +G C + SF C CP G G C D C ++ G C +P G
Sbjct: 693 PPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP--GSF 749
Query: 397 IC-TCPSGYT--GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE--- 450
C TCPSG+ C+ DVDECS GA PC G C NT GSF C C GY P
Sbjct: 750 QCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 808
Query: 451 -IDVNECVSNP-CQNDATCLDQIGEFQCICMPGY----EGVHCEVNTDECASSPCLHNGR 504
DVNEC+ C CL+ G F C C PGY G C ++ DEC+ +G
Sbjct: 809 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 867
Query: 505 CLDKINEFQCECPTGFTGH---LCQYDVDECAST-PCKNGA-KCLDGPNTYTCV--CTEG 557
C + F+C CP G DVDEC P G+ +C + P +Y CV C G
Sbjct: 868 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 927
Query: 558 Y----TGTHCEVDIDECD---PDPCHYGSCKDGVATFTC--LCRPGY---TGHHCETNIN 605
Y GT C+ D+DEC P+ C C++ ++ C C PGY G C+ +++
Sbjct: 928 YHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVD 984
Query: 606 ECSSQP-CRHGGTCQDRDNAYLCFCLKGTTGPN-----CEINLDDCASSPCDSGTCLDKI 659
EC ++ C CQ+ ++ C C +G G ++N + C + C +
Sbjct: 985 ECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVE 1044
Query: 660 DGYECAC--EPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF---------TCRCPEGY 708
+ C C P M + G + + R P
Sbjct: 1045 GSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTP 1104
Query: 709 HDPTCLSEVNECNSNPCVHGACRD----SLNGYKCDC--DPGWSGTNCDINNNECESNPC 762
S EC + AC + ++ +C C GW G+ C I C
Sbjct: 1105 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRIQQ-------C 1156
Query: 763 VNGGTCKDMTSGYVCTCREGFSGP----NCQTNINECA--SNPCLNQGTCIDDVAGYKCN 816
T + + +C G+ P + + +++EC + G C++ GY C
Sbjct: 1157 PGTETAEYQS---LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1213
Query: 817 CLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLS 876
C Y T + C + EC E
Sbjct: 1214 CSNGYYYHTQRL--------ECIDNDECADEE---------------------------- 1237
Query: 877 PCRHGASCQNTHGGYRCHCQ 896
P G C NT G Y C C+
Sbjct: 1238 PACEGGRCVNTVGSYHCTCE 1257
Score = 256 bits (653), Expect = 3e-67
Identities = 251/868 (28%), Positives = 346/868 (39%), Gaps = 160/868 (18%)
Query: 324 VNGWTGED----------CSENIDDCASAACFHGATCHDRVASFYCECPHG----RTGLL 369
+ WTG + C N C C R + + C C G G
Sbjct: 464 IPAWTGPEIPESGPSSGMCQRNPQVCGPGRCI------SRPSGYTCACDSGFRLSPQGTR 517
Query: 370 CHLNDAC--ISNPCNEGSNCDTNPVNGKAICTCPSGY-TGPACSQ--DVDECSLGANPCE 424
C D C + PC G C+ +P G C C G+ GP ++ DVDEC PC+
Sbjct: 518 CIDVDECRRVPPPCAPG-RCENSP--GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCD 574
Query: 425 HAGKCINTLGSFECQCLQGYT----GPRCEIDVNECVSNP--CQNDATCLDQIGEFQCIC 478
G+C NT GSF C C GY G C+ DV+EC +P C A C + G F+C+C
Sbjct: 575 -LGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVC 631
Query: 479 MPGYEGVHCEVNTDECASSPC-LHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECA 533
G+ G CE + DECA P GRC + F C CP GF G CQ DVDECA
Sbjct: 632 PAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECA 690
Query: 534 STP--CKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPD-PCHYGSCKDGVAT 586
+P C G +C + ++ CVC G+ G+ CE D+DEC+ C C + +
Sbjct: 691 RSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGS 748
Query: 587 FTCLCRPGYTGHHCE----TNINECSS--QPCRHGGTCQDRDNAYLCFCL------KGTT 634
F C P +GHH T+++ECSS PC G C + + ++ C C G
Sbjct: 749 FQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 806
Query: 635 GPNCEINLDDCASSPC--DSGTCLDKIDGYECACEPGYT----GSMCNINIDECAGNPCH 688
GP ++N +C G CL+ + C C PGY G+ C +++DEC+
Sbjct: 807 GPCADVN--ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLC 863
Query: 689 NGGTCEDGINGFTCRCPEGYH---DPTCLSEVNECNSN-PCVHGA--CRDSLNGYKC--D 740
G C + F C CP G+ D +V+EC P + G+ C +S Y+C D
Sbjct: 864 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 923
Query: 741 CDPGW----SGTNCDINNNEC-ESNPCVNGGT-CKDMTSGYVCT--CREGFS---GPNCQ 789
CDPG+ GT D++ EC E P + G C++ Y CT C G+ G CQ
Sbjct: 924 CDPGYHAGPEGTCDDVD--ECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ 981
Query: 790 TNINECASNP-CLNQGTCIDDVAGYKCNCLLPYTGAT----------CEVVLAPCAPSPC 838
+++EC + C C + ++C C Y GA CE + C + C
Sbjct: 982 -DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALC 1040
Query: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAG 898
N SF CVCP + + CV P R A T G + A
Sbjct: 1041 ENVEG--------SFLCVCPNS--PEEFDPMTGRCV--PPRTSAG---TFPGSQPQAPAS 1085
Query: 899 Y------------------------SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCL 934
SGR E D P+ C N + C C
Sbjct: 1086 PVLPARPPPPPLPRRPSTPRQGPVGSGRR-ECYFDTAAPDACDN--ILARNVTWQECCCT 1142
Query: 935 PGFR-GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCF 993
G G+ C I +C + C P+G + + +
Sbjct: 1143 VGEGWGSGCR--IQQCPGTETAEYQSL--CPHGRGYLAPSGDLSLRRDVDECQLFRDQVC 1198
Query: 994 NGGTCVDGINSFTCLCPPGF---TGSYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCTC-P 1048
G CV+ ++C C G+ T D +EC D +P GG C + GSY CTC P
Sbjct: 1199 KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
Query: 1049 QGYTGPNCQNLVHWCDSSPCKNGGKCWQ 1076
+ + V S N G CWQ
Sbjct: 1259 PLVLDGSQRRCVSNESQSLDDNLGVCWQ 1286
Score = 256 bits (653), Expect = 3e-67
Identities = 234/843 (27%), Positives = 354/843 (41%), Gaps = 131/843 (15%)
Query: 518 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYT----GTHCEVDIDECD-- 571
+G + +CQ + C +C+ P+ YTC C G+ GT C +D+DEC
Sbjct: 475 SGPSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 527
Query: 572 PDPCHYGSCKDGVATFTCLCRPGYTGH----HCETNINECSS--QPCRHGGTCQDRDNAY 625
P PC G C++ +F C+C PG+ C +++EC PC G C++ ++
Sbjct: 528 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGSF 585
Query: 626 LCFCLKGTT----GPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYTGSMCNINI 679
LC C G G +C+ ++D+C SP C G C + + C C G+ GS C ++
Sbjct: 586 LCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 644
Query: 680 DECAGNPCHNG-GTCEDGINGFTCRCPEGYHD---PTCLSEVNEC--NSNPCVHGACRDS 733
DECA P G G C++ F C CP G+ +V+EC + PC +G C ++
Sbjct: 645 DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT 704
Query: 734 LNGYKCDC----DPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC-TCREG--FSGP 786
++C C P +G+ C+ + +ECE++ G C + + C TC G
Sbjct: 705 EGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 763
Query: 787 NCQTNINECASN--PCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNG-- 841
C T+++EC+S PC G C + ++C+C Y + PCA + C G
Sbjct: 764 RC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP--GPCADVNECLEGDF 820
Query: 842 ----GECRQSEDYESFSCVCPTGW----QGQTCEVDINECVLSPCRHGASCQNTHGGYRC 893
GEC ++ SF+C C G+ +G +C +D++EC C NT G + C
Sbjct: 821 CFPHGECLNTDG--SFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFEC 877
Query: 894 HCQAGYSG----RNCETDIDDCRPNPCHNGGS--CTDGINTAFC--DCLPGF----RGTF 941
C G+ +C D+D+CR GS C + + C DC PG+ GT
Sbjct: 878 ICPPGHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 936
Query: 942 CEEDINECAS-DPCRNGA-NCTDCVDSYTCT--CPAGFS---GIHCENNTPDCTESSCFN 994
+D++EC P GA C + SY CT C G+ G C++ S C
Sbjct: 937 --DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGA 994
Query: 995 GGTCVDGINSFTCLCPPGFTGS----YCQHDVNECDS-QPCLHGGTCQDGCGSYRCTCPQ 1049
C + SF CLC G+ G+ +C DVNEC++ Q C++ GS+ C CP
Sbjct: 995 HAVCQNLPGSFQCLCDQGYEGARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCPN 1053
Query: 1050 GYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP-SGWTGLYCDVPSVSCEVAAQRQ 1108
+ + C G T + + P S P + + RQ
Sbjct: 1054 --SPEEFDPMTGRCVPPRTSAG-----TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQ 1106
Query: 1109 GV--DVARLCQHGGLCVDAGNT--------HHCRCQAGY-TGSYCEDLVDECSPSPCQNG 1157
G R C DA + C C G GS C + +C +
Sbjct: 1107 GPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR--IQQCPGTETAEY 1164
Query: 1158 ATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ--NGGTCLDLPNTYKCSCPRG--- 1212
+ + GY +A ++ ++DEC Q G C++ Y C C G
Sbjct: 1165 QSLCPHGRGY----LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY 1220
Query: 1213 -TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNEC 1271
TQ + C I+ D+C P C G CV+ VG Y CTC P V +G C
Sbjct: 1221 HTQRLEC-IDNDEC------ADEEPAC-EGGRCVNTVGSYHCTCEPPLV---LDGSQRRC 1269
Query: 1272 LSN 1274
+SN
Sbjct: 1270 VSN 1272
Score = 236 bits (603), Expect = 2e-61
Identities = 259/912 (28%), Positives = 347/912 (38%), Gaps = 206/912 (22%)
Query: 35 GKCEAANGTEACVCGGAF-VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGF 93
G+CE + G+ CVCG F GPR + C + CH V C LG
Sbjct: 534 GRCENSPGSFRCVCGPGFRAGPRAAE--------CLDVDECHRVPP--------PCDLG- 576
Query: 94 SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSCQQADPCASNPC 149
C N T + C CP G+ G SCQ D C +P
Sbjct: 577 ----------------RCEN-------TPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG 613
Query: 150 ANG-GQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
G G C S+ C CP F G C +DV+EC Q+P C G C N GS+ C C A
Sbjct: 614 LCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPA 672
Query: 209 THTGPNCERPYVPC--------SPSPCQNGGTCRPTGDVTHECACLPGF----TGQNCEE 256
G P PC SP PC G C T + + +C C GF G CE+
Sbjct: 673 ---GFRSRGPGAPCQDVDECARSPPPC-TYGRCENT-EGSFQCVCPMGFQPNTAGSECED 727
Query: 257 NIDDCPGNNCKNGGACVDGVNTYNCR-CPPEWTGQY-----CTEDVDECQLMPNACQNGG 310
+D+C + G CV+ ++ CR CP +G + CT DVDEC C G
Sbjct: 728 -VDECENHLACPGQECVNSPGSFQCRTCP---SGHHLHRGRCT-DVDECSSGAPPCGPHG 782
Query: 311 TCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLC 370
C NT G + C C G+ P GR G
Sbjct: 783 HCTNTEGSFRCSCAPGY--------------------------------RAPSGRPGPCA 810
Query: 371 HLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY-TGP--ACSQDVDECSLGANPCEHAG 427
+N+ + C C +G CTC GY GP A DVDECS + C+ +G
Sbjct: 811 DVNECLEGDFCFPHGECLN--TDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQ-SG 866
Query: 428 KCINTLGSFECQCLQGY-TGPRCE--IDVNECVSN--PCQNDATCLDQIGEFQCI--CMP 480
C NT GSFEC C G+ GP +DV+EC C + G ++C+ C P
Sbjct: 867 ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDP 926
Query: 481 GY----EGVHCEVNTDECAS-SPCLHNG-RCLDKINEFQC--ECPTGF---TGHLCQYDV 529
GY EG C+ + DEC P + RC + ++C C G+ G CQ DV
Sbjct: 927 GYHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DV 983
Query: 530 DECASTP-CKNGAKCLDGPNTYTCVCTEGYTGT----HCEVDIDECD--PDPCHYGSCKD 582
DEC + C A C + P ++ C+C +GY G HC VD++EC+ C C++
Sbjct: 984 DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCEN 1042
Query: 583 GVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGP------ 636
+F C+C + + C G + A L P
Sbjct: 1043 VEGSFLCVC--PNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRR 1100
Query: 637 ------------NCEINLDDCASSPCDSGTCLDKIDGYECACEPGY-TGSMCNINIDECA 683
E D A CD+ + EC C G GS C I +C
Sbjct: 1101 PSTPRQGPVGSGRRECYFDTAAPDACDN-ILARNVTWQECCCTVGEGWGSGC--RIQQCP 1157
Query: 684 G-NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC---NSNPCVHGACRDSLNGYKC 739
G C G G+ P G D + +V+EC C G C ++ GY C
Sbjct: 1158 GTETAEYQSLCPHG-RGYL--APSG--DLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1212
Query: 740 DCDPGW----SGTNCDINNNEC-ESNPCVNGGTCKDMTSGYVCTCREGF----SGPNCQT 790
C G+ C I+N+EC + P GG C + Y CTC S C +
Sbjct: 1213 YCSNGYYYHTQRLEC-IDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1271
Query: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLP-------YTGATC---EVVLAPCAPSPCRN 840
N ++ + N G C +V G C P YT C E CA P ++
Sbjct: 1272 NESQSLDD---NLGVCWQEV-GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQD 1327
Query: 841 GGECRQSEDYES 852
S+D+E+
Sbjct: 1328 ------SDDFEA 1333
Score = 228 bits (582), Expect = 4e-59
Identities = 200/625 (32%), Positives = 270/625 (43%), Gaps = 110/625 (17%)
Query: 743 PGWSGTNCDIN---NNECESNPCVNG-GTCKDMTSGYVCTCREGF----SGPNCQTNINE 794
P W+G + + C+ NP V G G C SGY C C GF G C +++E
Sbjct: 465 PAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDE 523
Query: 795 C--ASNPCLNQGTCIDDVAGYKCNC-----LLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
C PC G C + ++C C P +V P PC + G C +
Sbjct: 524 CRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPC-DLGRCENT 581
Query: 848 EDYESFSCVCPTGWQ----GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSG 901
SF CVCP G+Q G +C+ D++EC SP C GA C+N G +RC C AG+ G
Sbjct: 582 PG--SFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRG 637
Query: 902 RNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASD--P 953
CE D+D+C P PC G C + + C C GFR G C +D++ECA P
Sbjct: 638 SACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPP 695
Query: 954 CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTC-L 1008
C G C + S+ C CP GF +G CE + +C G CV+ SF C
Sbjct: 696 CTYG-RCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRT 753
Query: 1009 CPPG--FTGSYCQHDVNECDS--QPCLHGGTCQDGCGSYRCTCPQGYTGPN-----CQNL 1059
CP G C DV+EC S PC G C + GS+RC+C GY P+ C ++
Sbjct: 754 CPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 812
Query: 1060 VHWCDSSPCKNGGKCWQTHTQYRCECPSGW----TGLYC-DVPSVSCEVAAQRQGVDVAR 1114
+ C G+C T + C C G+ G C DV S E
Sbjct: 813 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE-----------D 861
Query: 1115 LCQHGGLCVDAGNTHHCRCQAGYTG----SYCEDLVDEC---SPSPCQNGATCTDYLGGY 1167
LCQ G+C + + C C G+ + C D VDEC P+ C C + G Y
Sbjct: 862 LCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD-VDECRERGPALC-GSQRCENSPGSY 918
Query: 1168 SC--KCVAGYHG--VNCSEEIDECLSHPCQNGGT--CLDLPNTYKC--SCPRG---TQGV 1216
C C GYH +++DEC + + G C + P +Y+C +C G T G
Sbjct: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 978
Query: 1217 HCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG----DVNEC- 1271
C+ +VD+C +RS C + C + G + C C G+ G R +G DVNEC
Sbjct: 979 GCQ-DVDECR------NRS-FCGAHAVCQNLPGSFQCLCDQGYEGAR-DGRHCVDVNECE 1029
Query: 1272 -LSNPCDARGTQNCVQRVNDFHCEC 1295
L C G C F C C
Sbjct: 1030 TLQGVC---GAALCENVEGSFLCVC 1051
Score = 227 bits (578), Expect = 1e-58
Identities = 225/808 (27%), Positives = 318/808 (39%), Gaps = 164/808 (20%)
Query: 645 CASSP--CDSGTCLDKIDGYECACEPGYT----GSMCNINIDEC--AGNPCHNGGTCEDG 696
C +P C G C+ + GY CAC+ G+ G+ C I++DEC PC G CE+
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENS 539
Query: 697 INGFTCRCPEGYHD----PTCLSEVNECNS--NPCVHGACRDSLNGYKCDCDPGWS---- 746
F C C G+ CL +V+EC+ PC G C ++ + C C G+
Sbjct: 540 PGSFRCVCGPGFRAGPRAAECL-DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPH 598
Query: 747 GTNCDINNNECESNPCVNG-GTCKDMTSGYVCTCREGFSGPNCQTNINECASNPC-LNQG 804
G +C + +EC +P + G G CK++ + C C GF G C+ +++ECA P G
Sbjct: 599 GASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG 657
Query: 805 TCIDDVAGYKCNCLLPYT----GATCEVVLAPCA--PSPCRNGGECRQSEDYESFSCVCP 858
C + + C C + GA C+ V CA P PC G C +E SF CVCP
Sbjct: 658 RCDNTAGSFHCACPAGFRSRGPGAPCQDV-DECARSPPPCTYG-RCENTEG--SFQCVCP 713
Query: 859 TGWQ----GQTCEVDINECVLSPCRHGASCQNTHGGYRCH-CQAGYS-GRNCETDIDDCR 912
G+Q G CE D++EC G C N+ G ++C C +G+ R TD+D+C
Sbjct: 714 MGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECS 772
Query: 913 PN--PCHNGGSCTDGINTAFCDCLPGFRGTFCEE----DINECAS-DPCRNGANCTDCVD 965
PC G CT+ + C C PG+R D+NEC D C C +
Sbjct: 773 SGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG 832
Query: 966 SYTCTCPAGFS----GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTG----SY 1017
S+ CTC G+ G C + +C+E G C + SF C+CPPG +
Sbjct: 833 SFACTCAPGYRPGPRGASCLD-VDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLAS 891
Query: 1018 CQHDVNEC------------------------DSQPCLHGGT------------------ 1035
C DV+EC D P H G
Sbjct: 892 CL-DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC 950
Query: 1036 ----CQDGCGSYRCT--CPQGYT---GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP 1086
C++ GSYRCT C GY G CQ++ + S C C ++C C
Sbjct: 951 GAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCD 1010
Query: 1087 SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH---GGLCVDAGN-------THHC---RC 1133
G+ G V QGV A LC++ LCV + T C R
Sbjct: 1011 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT 1070
Query: 1134 QAG-YTGSYCEDLVDECSPS-------PCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI- 1184
AG + GS + P+ P + +G +C + + I
Sbjct: 1071 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNIL 1130
Query: 1185 ------DECLSHPCQNGGTCLDL---PNT----YKCSCPRG------TQGVHCEINVDDC 1225
EC + G+ + P T Y+ CP G + + +VD+C
Sbjct: 1131 ARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1190
Query: 1226 NPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV--GERCEG-DVNECLSNPCDARGTQ 1282
D V +S G CV+ GYSC C G+ +R E D +EC G +
Sbjct: 1191 QLFRDQVCKS------GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1244
Query: 1283 NCVQRVNDFHCECR----AGHTGRRCES 1306
CV V +HC C + RRC S
Sbjct: 1245 -CVNTVGSYHCTCEPPLVLDGSQRRCVS 1271
Score = 209 bits (532), Expect = 3e-53
Identities = 187/625 (29%), Positives = 256/625 (40%), Gaps = 138/625 (22%)
Query: 884 CQNTHGGYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGF 937
C + GY C C +G+ G C D+D+CR P PC G C + + C C PGF
Sbjct: 494 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGF 551
Query: 938 R-GTFCEE--DINEC--ASDPCRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCT 988
R G E D++EC PC G C + S+ C CPAG+ G C++ +CT
Sbjct: 552 RAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD-VDECT 609
Query: 989 ESSCFNG-GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSYRCT 1046
+S G G C + SF C+CP GF GS C+ DV+EC +P G G C + GS+ C
Sbjct: 610 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA 669
Query: 1047 CPQGY----TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE 1102
CP G+ G CQ++ S P G+C T ++C CP G+ + CE
Sbjct: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP---NTAGSECE 726
Query: 1103 VAAQRQGVDVARLCQHGGLCVDAGNTHHCR-CQAGY--TGSYCEDLVDECSPS--PCQNG 1157
+ + L G CV++ + CR C +G+ C D VDECS PC
Sbjct: 727 DVDECEN----HLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTD-VDECSSGAPPCGPH 781
Query: 1158 ATCTDYLGGYSCKCVAGYHGVN-----CSEEIDECLSHP-CQNGGTCLDLPNTYKCSCP- 1210
CT+ G + C C GY + C+ +++ECL C G CL+ ++ C+C
Sbjct: 782 GHCTNTEGSFRCSCAPGYRAPSGRPGPCA-DVNECLEGDFCFPHGECLNTDGSFACTCAP 840
Query: 1211 ---RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGD 1267
G +G C ++VD+C S C +G C + G + C CPP G R D
Sbjct: 841 GYRPGPRGASC-LDVDEC-------SEEDLC-QSGICTNTDGSFECICPP---GHRAGPD 888
Query: 1268 VNECLS-NPCDAR-----GTQNCVQRVNDFHC--ECRAG-HTG----------------- 1301
+ CL + C R G+Q C + C +C G H G
Sbjct: 889 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 948
Query: 1302 ----RRCESVINGCKGKP-------------------CKNGGTC---AVASNTARGFICK 1335
+RCE+ + P C+N C AV N F C
Sbjct: 949 ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1008
Query: 1336 CPAGFEGA----------TCENDARTCGSLRCLN--GGTCISGPRSP------TCLCL-- 1375
C G+EGA CE CG+ C N G P SP T C+
Sbjct: 1009 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1068
Query: 1376 ----GPFTGPECQFPASSPCLGGNP 1396
G F G + Q PA SP L P
Sbjct: 1069 RTSAGTFPGSQPQAPA-SPVLPARP 1092
Score = 163 bits (412), Expect = 2e-39
Identities = 230/872 (26%), Positives = 330/872 (37%), Gaps = 151/872 (17%)
Query: 779 CREGFSGPN--CQTNINECASNPCLNQGTCIDDVAGYKCNC----LLPYTGATC--EVVL 830
C GF N C+ +++ECA+ G C + GY C C LL + ++C + V+
Sbjct: 277 CPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
Query: 831 APCAPSPC----RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQN 886
+ A PC R+GG C +C G+ C L P G+
Sbjct: 336 SE-AKGPCFRVLRDGG-CSLPILRNITKQICCCSRVGKAWG---RGCQLCP-PFGSE--- 386
Query: 887 THGGYRCHCQAGYSGRNCETDID-DCRPNPCHNGGSCTDGINTAFCDCLP--GFRGTFCE 943
G+R C AG +D+ + RP T P GF T
Sbjct: 387 ---GFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRL 443
Query: 944 EDINECASDPCRNGANCTDCVDSYTCT--CPAGFSGIHCENNTPDCTESSCFNGGTCVDG 1001
E E DP + ++T +G S C+ N C G C+
Sbjct: 444 EPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC------GPGRCISR 497
Query: 1002 INSFTCLCPPGFT----GSYCQHDVNECDS--QPCLHGGTCQDGCGSYRCTCPQGY-TGP 1054
+ +TC C GF G+ C DV+EC PC G C++ GS+RC C G+ GP
Sbjct: 498 PSGYTCACDSGFRLSPQGTRCI-DVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGP 555
Query: 1055 N---CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVD 1111
C ++ P + G+C T + C CP+G+ + Q G
Sbjct: 556 RAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG-- 613
Query: 1112 VARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSC 1169
LC G C + + C C AG+ GS CE+ VDEC+ P PC G C + G + C
Sbjct: 614 ---LCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR-CDNTAGSFHC 668
Query: 1170 KCVAGYH----GVNCSEEIDECL-SHPCQNGGTCLDLPNTYKCSCPRG----TQGVHCEI 1220
C AG+ G C +++DEC S P G C + +++C CP G T G CE
Sbjct: 669 ACPAGFRSRGPGAPC-QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE- 726
Query: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC-TCPPG--FVGERCEGDVNECLSN--P 1275
+VD+C + + CV+ G + C TCP G RC DV+EC S P
Sbjct: 727 DVDECENHLACPGQE--------CVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSGAPP 777
Query: 1276 CDARGTQNCVQRVNDFHCECRAGH---TGRR--CESVINGCKGKPCKNGGTCAVASNTAR 1330
C G +C F C C G+ +GR C V +G C G C NT
Sbjct: 778 CGPHG--HCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECL---NTDG 832
Query: 1331 GFICKCPAGFE----GATCENDARTCGSLRCLNGGTCISGPRSPTCLCL-GPFTGPECQF 1385
F C C G+ GA+C D C G C + S C+C G GP+
Sbjct: 833 SFACTCAPGYRPGPRGASCL-DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL-- 889
Query: 1386 PASSPCLGGNPCYNQGT-------CEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGR 1438
+ CL + C +G CE + S YRC + D G AG
Sbjct: 890 ---ASCLDVDECRERGPALCGSQRCENSPGS--YRC------------VRDCDPGYHAGP 932
Query: 1439 DIPPPLIEEA-------CELPECQEDAGNKVCSLQCNNHACGWDGGDCS----------L 1481
+ ++E C C+ G+ C+ C+ GG C
Sbjct: 933 EGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFC 992
Query: 1482 NFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFS 1541
+ +N S QC D + + C+ D +C+ +G C C++
Sbjct: 993 GAHAVCQNLPGSFQC---LCDQGYEGARDGRHCV-DVNECETLQGVCGA---ALCENVEG 1045
Query: 1542 DGHCDQGCNSAECEWDGLDCAEHVPERLAAGT 1573
C C ++ E+D + VP R +AGT
Sbjct: 1046 SFLC--VCPNSPEEFDPM-TGRCVPPRTSAGT 1074
Score = 125 bits (313), Expect = 7e-28
Identities = 142/531 (26%), Positives = 187/531 (35%), Gaps = 117/531 (22%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPR-----CQDPNPCLSTP-CKNAGTCHVV 77
CS C G C G+ C C + P C D N CL C G C
Sbjct: 771 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNT 830
Query: 78 DRRGVADYACSCALGF-SGPLCLTPLD-NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSG 135
D +AC+CA G+ GP + LD + C G C T ++C CPPG
Sbjct: 831 D----GSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC-TNTDGSFECICPPGHRA 885
Query: 136 ----KSCQQADPCAS-NPCANGGQ-CLPFEASYIC--HCPPSFH-GP--TCRQDVNECGQ 184
SC D C P G Q C SY C C P +H GP TC DV+EC +
Sbjct: 886 GPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC-DDVDECQE 944
Query: 185 -KPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHEC 243
P +C C N GSYRC P C+ Y P CQ+ CR
Sbjct: 945 YGPEIC-GAQRCENTPGSYRCT-------PACDPGYQPTPGGGCQDVDECRNRSFCGAHA 996
Query: 244 AC--LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQL 301
C LPG C++ + ++G CV DV+EC+
Sbjct: 997 VCQNLPGSFQCLCDQGYE-----GARDGRHCV---------------------DVNECET 1030
Query: 302 MPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC----ASAACFHGATCH------ 351
+ C C N G + CVC N + E+ C SA F G+
Sbjct: 1031 LQGVC-GAALCENVEGSFLCVCPN--SPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPV 1087
Query: 352 ----------DRVASFYCECPHGRTGLLCHLNDA------------------CISNPCNE 383
R S + P G C+ + A C +
Sbjct: 1088 LPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW 1147
Query: 384 GSNC------DTNPVNGKAICTCPSGYTGP----ACSQDVDECSLGANPCEHAGKCINTL 433
GS C T +++C GY P + +DVDEC L + +G C+NT
Sbjct: 1148 GSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTA 1207
Query: 434 GSFECQCLQG--YTGPRCE-IDVNECV-SNPCQNDATCLDQIGEFQCICMP 480
+ C C G Y R E ID +EC P C++ +G + C C P
Sbjct: 1208 PGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
Score = 52.8 bits (125), Expect = 4e-06
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 11/83 (13%)
Query: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNEC----VSNPCQN 463
+ +EC + + C + G+C+ F C+C GY T C +D+NEC ++P
Sbjct: 1466 EAEECGI-LDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1522
Query: 464 DATCLDQIGEFQCICMPGYEGVH 486
+A CL+ G F+CIC PG+ H
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTH 1545
Score = 49.7 bits (117), Expect = 4e-05
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 526 QYDVDECASTP-CKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPDP-----C 575
+ + +EC C NG +C+ P +TC C +GY T C VDI+ECD C
Sbjct: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLC 1521
Query: 576 HYGSCKDGVATFTCLCRPGYT----GHHC 600
C + +F C+CRPG+ HHC
Sbjct: 1522 VNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 7/82 (8%)
Query: 488 EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQY---DVDEC----ASTPCKNG 540
E+ +EC NGRC+ F C C G+ + + D++EC A++P
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 541 AKCLDGPNTYTCVCTEGYTGTH 562
A+CL+ ++ C+C G+ TH
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTH 1545
Score = 47.0 bits (110), Expect = 2e-04
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 12/92 (13%)
Query: 670 YTGSMCN----INIDECAGNPCHNGGTCEDGINGFTCRCPEGYH-DPTCLS--EVNECN- 721
Y GS+ + +EC G C GFTCRC +GY D T ++ ++NEC+
Sbjct: 1454 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDE 1513
Query: 722 ----SNPCVHGACRDSLNGYKCDCDPGWSGTN 749
S CV+ C ++ ++C C PG++ T+
Sbjct: 1514 AEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
Score = 40.4 bits (93), Expect = 0.023
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 10/70 (14%)
Query: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCE---VDINEC----VLSPCRHGASCQNTHGG 890
C NG R E F+C C G++ VDINEC SP A C NT G
Sbjct: 1476 CTNGRCVRVPE---GFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1532
Query: 891 YRCHCQAGYS 900
+RC C+ G++
Sbjct: 1533 FRCICRPGFA 1542
Score = 39.7 bits (91), Expect = 0.038
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 1183 EIDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1241
E +EC + C NG C+ +P + C C G + + D N + + SP C N
Sbjct: 1466 EAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN- 1523
Query: 1242 GTCVDQVGGYSCTCPPGF 1259
C++ G + C C PGF
Sbjct: 1524 ARCLNTDGSFRCICRPGF 1541
Score = 38.5 bits (88), Expect = 0.086
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 10/68 (14%)
Query: 992 CFNGGTCVDGINSFTCLCPPGF----TGSYCQHDVNECD----SQPCLHGGTCQDGCGSY 1043
C NG CV FTC C G+ T C D+NECD + P C + GS+
Sbjct: 1476 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACV-DINECDEAEAASPLCVNARCLNTDGSF 1533
Query: 1044 RCTCPQGY 1051
RC C G+
Sbjct: 1534 RCICRPGF 1541
Score = 38.1 bits (87), Expect = 0.11
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 11/86 (12%)
Query: 140 QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQ---DVNECGQKPG---LCRHGG 193
+A+ C G+C+ + C C + R D+NEC + LC +
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA- 1524
Query: 194 TCHNEVGSYRCVCR----ATHTGPNC 215
C N GS+RC+CR TH +C
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 37.4 bits (85), Expect = 0.19
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 21/92 (22%)
Query: 943 EEDINECAS-DPCRNGANCTDCVDSYTCTCPAGF----SGIHC---------ENNTPDCT 988
E + EC D C NG C + +TC C G+ + + C E +P C
Sbjct: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 989 ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH 1020
+ C N DG SF C+C PGF ++ H
Sbjct: 1523 NARCLN----TDG--SFRCICRPGFAPTHQPH 1548
Score = 36.6 bits (83), Expect = 0.33
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 11/87 (12%)
Query: 636 PNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYTGSMCN---INIDEC----AGNPC 687
P E+ ++C C +G C+ +G+ C C GY M ++I+EC A +P
Sbjct: 1461 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1520
Query: 688 HNGGTCEDGINGFTCRCPEGY---HDP 711
C + F C C G+ H P
Sbjct: 1521 CVNARCLNTDGSFRCICRPGFAPTHQP 1547
Score = 33.9 bits (76), Expect = 2.1
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 12/79 (15%)
Query: 716 EVNECNS-NPCVHGACRDSLNGYKCDCDPGW----SGTNCDINNNECE-----SNPCVNG 765
E EC + C +G C G+ C C G+ + C ++ NEC+ S CVN
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNA 1524
Query: 766 GTCKDMTSGYVCTCREGFS 784
C + + C CR GF+
Sbjct: 1525 -RCLNTDGSFRCICRPGFA 1542
Score = 33.5 bits (75), Expect = 2.8
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 13/106 (12%)
Query: 1352 CGSLRCLNGGT---CIS--GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPT 1406
CG LRC++G T C PR+ T + G G P L C+N G C
Sbjct: 41 CG-LRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKP 99
Query: 1407 SESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELP 1452
RCLCP F G C + +S G P L +P
Sbjct: 100 D-----RCLCPPDFAGKFCQL--HSSGARPPAPAVPGLTRSVYTMP 138
Score = 33.1 bits (74), Expect = 3.6
Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 17/101 (16%)
Query: 1132 RCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP 1191
RC G TGS C C+P +N + G + G+ C
Sbjct: 44 RCVHGPTGSRC---TPTCAP---RNATSVDSGAPGGAAPGGPGFRAFLCPLI-------- 89
Query: 1192 CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPV 1232
C NGG C+ P+ +C CP G C+++ PP V
Sbjct: 90 CHNGGVCVK-PD--RCLCPPDFAGKFCQLHSSGARPPAPAV 127
Score = 33.1 bits (74), Expect = 3.6
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 867 EVDINEC-VLSPCRHGASCQNTHGGYRCHCQAGY---SGRNCETDIDDC----RPNPCHN 918
E++ EC +L C +G C G+ C C GY R DI++C +P
Sbjct: 1464 ELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 919 GGSCTDGINTAFCDCLPGFRGT 940
C + + C C PGF T
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPT 1544
Score = 33.1 bits (74), Expect = 3.6
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 8/70 (11%)
Query: 264 NNCKNGGACVDGVNTYNCRCPP----EWTGQYCTE--DVDECQLMPNACQNGGTCHNTHG 317
+ C NG CV + CRC + T C + + DE + C N C NT G
Sbjct: 1474 DGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA-RCLNTDG 1531
Query: 318 GYNCVCVNGW 327
+ C+C G+
Sbjct: 1532 SFRCICRPGF 1541
Score = 32.3 bits (72), Expect = 6.1
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 14/107 (13%)
Query: 1242 GTCVDQVGGYSCTCP-PGFVGER--CEG-----DVNECLSNPCDARGTQNCVQRVNDFHC 1293
G C ++ G C P PG + C G V++C C R + D C
Sbjct: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDC--QLCSERLGNSERVSAPDGPC 277
Query: 1294 ECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1340
CE V G C++G CA NT G+ C CP GF
Sbjct: 278 PTGFERVNGSCEDVDECATGGRCQHG-ECA---NTRGGYTCVCPDGF 320
Score = 32.0 bits (71), Expect = 8.0
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 15/94 (15%)
Query: 1137 YTGSYCEDL----VDECSP-SPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDEC 1187
Y GS E +EC C NG C G++C+C GY + C +I+EC
Sbjct: 1454 YAGSLAEPYEELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMAC-VDINEC 1511
Query: 1188 ----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
+ P CL+ +++C C G H
Sbjct: 1512 DEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
Score = 32.0 bits (71), Expect = 8.0
Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ---TNINEC----ASNPCLNQ 803
++ EC G C + G+ C C +G+ + +INEC A++P
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 804 GTCIDDVAGYKCNC 817
C++ ++C C
Sbjct: 1524 ARCLNTDGSFRCIC 1537
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 269 bits (687), Expect = 3e-71
Identities = 339/1278 (26%), Positives = 475/1278 (37%), Gaps = 290/1278 (22%)
Query: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ----ADPCA-----------SNPCAN---- 151
C NGG C + +C CPP ++GK CQ A P A + P AN
Sbjct: 120 CHNGGVC----VKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDD 175
Query: 152 --GGQCL-------PFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSY 202
G + P EAS + H GP D + R V +
Sbjct: 176 EHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQ 235
Query: 203 RC-------------VCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV--THECACLP 247
C G C P P CR G H+C
Sbjct: 236 SAPREDGYSDASGFGYCFRELRGGECASPL----PGLRTQEVCCRGAGLAWGVHDC---- 287
Query: 248 GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
Q C E + + + +G C G N C EDVDEC CQ
Sbjct: 288 ----QLCSERLGNSERVSAPDG-PCPTGFERVNGSC----------EDVDECAT-GGRCQ 331
Query: 308 NGGTCHNTHGGYNCVCVNGW----TGEDC-SENIDDCASAACFHGATCHDRVASFYCECP 362
+G C NT GGY CVC +G+ + C S+++ A CF + C P
Sbjct: 332 HG-ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR------VLRDGGCSLP 384
Query: 363 HGR--TGLLCHLNDACISNPCNEGSNCDTNPVNG----KAICTCPSGYTGPACSQDVDEC 416
R T +C C G C P G + IC GY A +
Sbjct: 385 ILRNITKQIC----CCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTR 440
Query: 417 SLGANPCEHAGKCINTLGS-----------------------------FECQCLQGYTGP 447
LG P + TL + + +TGP
Sbjct: 441 PLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGP 500
Query: 448 RCEIDVNECVSNPCQND------ATCLDQIGEFQCICMPGY----EGVHCEVNTDEC--A 495
EI + S CQ + C+ + + C C G+ +G C ++ DEC
Sbjct: 501 --EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 557
Query: 496 SSPCLHNGRCLDKINEFQCECPTGF----TGHLCQYDVDEC--ASTPCKNGAKCLDGPNT 549
PC GRC + F+C C GF C DVDEC PC G +C + P +
Sbjct: 558 PPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGS 614
Query: 550 YTCVCTEGYT----GTHCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETN 603
+ CVC GY G C+ D+DEC P C G+CK+ +F C+C G+ G CE +
Sbjct: 615 FLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 673
Query: 604 INECSSQPCRHG-GTCQDRDNAYLCFCLKG--TTGPN--CEINLDDCASS--PCDSGTCL 656
++EC+ +P G G C + ++ C C G + GP C+ ++D+CA S PC G C
Sbjct: 674 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCE 732
Query: 657 DKIDGYECAC----EPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR-CPEGYH-D 710
+ ++C C +P GS C ++DEC + G C + F CR CP G+H
Sbjct: 733 NTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH 791
Query: 711 PTCLSEVNECNSN--PC-VHGACRDSLNGYKCDCDPGW------SGTNCDINNNEC-ESN 760
++V+EC+S PC HG C ++ ++C C PG+ G D+ NEC E +
Sbjct: 792 RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV--NECLEGD 849
Query: 761 PCVNGGTCKDMTSGYVCTCREGF----SGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
C G C + + CTC G+ G +C +++EC+ G C + ++C
Sbjct: 850 FCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECI 908
Query: 817 CLLPYTGATCEVVLAPCAP-SPCRNGGEC-----RQSEDYESFSCV--CPTGWQG---QT 865
C G LA C CR G R S+ CV C G+ T
Sbjct: 909 C---PPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 965
Query: 866 CEVDINEC-VLSPCRHGAS-CQNTHGGYRC--HCQAGYS---GRNCETDIDDCRPNP-CH 917
C+ D++EC P GA C+NT G YRC C GY G C+ D+D+CR C
Sbjct: 966 CD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCG 1023
Query: 918 NGGSCTDGINTAFCDCLPGFRGT----FCEEDINECAS-DPCRNGANCTDCVDSYTCTCP 972
C + + C C G+ G C D+NEC + A C + S+ C CP
Sbjct: 1024 AHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1082
Query: 973 AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL- 1031
N+P+ + G CV PP + + + P L
Sbjct: 1083 ----------NSPEEFDPMT---GRCV----------PPRTSAGTFPGSQPQAPASPVLP 1119
Query: 1032 ----------HGGTCQDG-CGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ 1080
T + G GS R C P+ CD+ +N WQ +
Sbjct: 1120 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDA------CDNILARN--VTWQ---E 1168
Query: 1081 YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG-GLCVDAGNTHHCRCQAGYTG 1139
C GW G C + A+ Q LC HG G +G+ R
Sbjct: 1169 CCCTVGEGW-GSGCRIQQCPGTETAEYQS-----LCPHGRGYLAPSGDLSLRRD------ 1216
Query: 1140 SYCEDLVDECS---PSPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDECL-SHP 1191
VDEC C++G C + GYSC C GY+ + C + DEC P
Sbjct: 1217 ------VDECQLFRDQVCKSG-VCVNTAPGYSCYCSNGYYYHTQRLECIDN-DECADEEP 1268
Query: 1192 CQNGGTCLDLPNTYKCSC 1209
GG C++ +Y C+C
Sbjct: 1269 ACEGGRCVNTVGSYHCTC 1286
Score = 259 bits (661), Expect = 3e-68
Identities = 240/860 (27%), Positives = 336/860 (39%), Gaps = 161/860 (18%)
Query: 131 PGWSGKSCQQADP----CASNPCANG-GQCLPFEASYICHCPPSFH----GPTCRQDVNE 181
P W+G ++ P C NP G G+C+ + Y C C F G C DV+E
Sbjct: 495 PAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCI-DVDE 553
Query: 182 CGQKPGLCRHGGTCHNEVGSYRCVCR-ATHTGPN---------CERPYVPCSPSPCQNGG 231
C + P C G C N GS+RCVC GP C R PC C+N
Sbjct: 554 CRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP 612
Query: 232 TCRPTGDVTHECACLPGFT----GQNCEENIDDCPGNNCKNG-GACVDGVNTYNCRCPPE 286
+ C C G+ G +C++ +D+C + G GAC + ++ C CP
Sbjct: 613 G-------SFLCVCPAGYQAAPHGASCQD-VDECTQSPGLCGRGACKNLPGSFRCVCPAG 664
Query: 287 WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT----GEDCSENIDDCASA 342
+ G C EDVDEC P C G C NT G ++C C G+ G C +++D+CA +
Sbjct: 665 FRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARS 722
Query: 343 A--CFHGATCHDRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKA 396
C +G C + SF C CP G G C D C ++ G C +P G
Sbjct: 723 PPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP--GSF 779
Query: 397 IC-TCPSGYT--GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE--- 450
C TCPSG+ C+ DVDECS GA PC G C NT GSF C C GY P
Sbjct: 780 QCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 838
Query: 451 -IDVNECVSNP-CQNDATCLDQIGEFQCICMPGY----EGVHCEVNTDECASSPCLHNGR 504
DVNEC+ C CL+ G F C C PGY G C ++ DEC+ +G
Sbjct: 839 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 897
Query: 505 CLDKINEFQCECPTGFTGH---LCQYDVDECAST-PCKNGA-KCLDGPNTYTCV--CTEG 557
C + F+C CP G DVDEC P G+ +C + P +Y CV C G
Sbjct: 898 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 957
Query: 558 Y----TGTHCEVDIDECD---PDPCHYGSCKDGVATFTC--LCRPGY---TGHHCETNIN 605
Y GT C+ D+DEC P+ C C++ ++ C C PGY G C+ +++
Sbjct: 958 YHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVD 1014
Query: 606 ECSSQP-CRHGGTCQDRDNAYLCFCLKGTTGPN-----CEINLDDCASSPCDSGTCLDKI 659
EC ++ C CQ+ ++ C C +G G ++N + C + C +
Sbjct: 1015 ECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVE 1074
Query: 660 DGYECAC--EPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF---------TCRCPEGY 708
+ C C P M + G + + R P
Sbjct: 1075 GSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTP 1134
Query: 709 HDPTCLSEVNECNSNPCVHGACRD----SLNGYKCDC--DPGWSGTNCDINNNECESNPC 762
S EC + AC + ++ +C C GW G+ C I C
Sbjct: 1135 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRIQQ-------C 1186
Query: 763 VNGGTCKDMTSGYVCTCREGFSGP----NCQTNINECA--SNPCLNQGTCIDDVAGYKCN 816
T + + +C G+ P + + +++EC + G C++ GY C
Sbjct: 1187 PGTETAEYQS---LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1243
Query: 817 CLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLS 876
C Y T + C + EC E
Sbjct: 1244 CSNGYYYHTQRL--------ECIDNDECADEE---------------------------- 1267
Query: 877 PCRHGASCQNTHGGYRCHCQ 896
P G C NT G Y C C+
Sbjct: 1268 PACEGGRCVNTVGSYHCTCE 1287
Score = 256 bits (653), Expect = 3e-67
Identities = 251/868 (28%), Positives = 346/868 (39%), Gaps = 160/868 (18%)
Query: 324 VNGWTGED----------CSENIDDCASAACFHGATCHDRVASFYCECPHG----RTGLL 369
+ WTG + C N C C R + + C C G G
Sbjct: 494 IPAWTGPEIPESGPSSGMCQRNPQVCGPGRCI------SRPSGYTCACDSGFRLSPQGTR 547
Query: 370 CHLNDAC--ISNPCNEGSNCDTNPVNGKAICTCPSGY-TGPACSQ--DVDECSLGANPCE 424
C D C + PC G C+ +P G C C G+ GP ++ DVDEC PC+
Sbjct: 548 CIDVDECRRVPPPCAPG-RCENSP--GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCD 604
Query: 425 HAGKCINTLGSFECQCLQGYT----GPRCEIDVNECVSNP--CQNDATCLDQIGEFQCIC 478
G+C NT GSF C C GY G C+ DV+EC +P C A C + G F+C+C
Sbjct: 605 -LGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVC 661
Query: 479 MPGYEGVHCEVNTDECASSPC-LHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECA 533
G+ G CE + DECA P GRC + F C CP GF G CQ DVDECA
Sbjct: 662 PAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECA 720
Query: 534 STP--CKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPD-PCHYGSCKDGVAT 586
+P C G +C + ++ CVC G+ G+ CE D+DEC+ C C + +
Sbjct: 721 RSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGS 778
Query: 587 FTCLCRPGYTGHHCE----TNINECSS--QPCRHGGTCQDRDNAYLCFCL------KGTT 634
F C P +GHH T+++ECSS PC G C + + ++ C C G
Sbjct: 779 FQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 836
Query: 635 GPNCEINLDDCASSPC--DSGTCLDKIDGYECACEPGYT----GSMCNINIDECAGNPCH 688
GP ++N +C G CL+ + C C PGY G+ C +++DEC+
Sbjct: 837 GPCADVN--ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLC 893
Query: 689 NGGTCEDGINGFTCRCPEGYH---DPTCLSEVNECNSN-PCVHGA--CRDSLNGYKC--D 740
G C + F C CP G+ D +V+EC P + G+ C +S Y+C D
Sbjct: 894 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 953
Query: 741 CDPGW----SGTNCDINNNEC-ESNPCVNGGT-CKDMTSGYVCT--CREGFS---GPNCQ 789
CDPG+ GT D++ EC E P + G C++ Y CT C G+ G CQ
Sbjct: 954 CDPGYHAGPEGTCDDVD--ECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ 1011
Query: 790 TNINECASNP-CLNQGTCIDDVAGYKCNCLLPYTGAT----------CEVVLAPCAPSPC 838
+++EC + C C + ++C C Y GA CE + C + C
Sbjct: 1012 -DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALC 1070
Query: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAG 898
N SF CVCP + + CV P R A T G + A
Sbjct: 1071 ENVEG--------SFLCVCPNS--PEEFDPMTGRCV--PPRTSAG---TFPGSQPQAPAS 1115
Query: 899 Y------------------------SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCL 934
SGR E D P+ C N + C C
Sbjct: 1116 PVLPARPPPPPLPRRPSTPRQGPVGSGRR-ECYFDTAAPDACDN--ILARNVTWQECCCT 1172
Query: 935 PGFR-GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCF 993
G G+ C I +C + C P+G + + +
Sbjct: 1173 VGEGWGSGCR--IQQCPGTETAEYQSL--CPHGRGYLAPSGDLSLRRDVDECQLFRDQVC 1228
Query: 994 NGGTCVDGINSFTCLCPPGF---TGSYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCTC-P 1048
G CV+ ++C C G+ T D +EC D +P GG C + GSY CTC P
Sbjct: 1229 KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Query: 1049 QGYTGPNCQNLVHWCDSSPCKNGGKCWQ 1076
+ + V S N G CWQ
Sbjct: 1289 PLVLDGSQRRCVSNESQSLDDNLGVCWQ 1316
Score = 256 bits (653), Expect = 3e-67
Identities = 234/843 (27%), Positives = 354/843 (41%), Gaps = 131/843 (15%)
Query: 518 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYT----GTHCEVDIDECD-- 571
+G + +CQ + C +C+ P+ YTC C G+ GT C +D+DEC
Sbjct: 505 SGPSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 557
Query: 572 PDPCHYGSCKDGVATFTCLCRPGYTGH----HCETNINECSS--QPCRHGGTCQDRDNAY 625
P PC G C++ +F C+C PG+ C +++EC PC G C++ ++
Sbjct: 558 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGSF 615
Query: 626 LCFCLKGTT----GPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYTGSMCNINI 679
LC C G G +C+ ++D+C SP C G C + + C C G+ GS C ++
Sbjct: 616 LCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 674
Query: 680 DECAGNPCHNG-GTCEDGINGFTCRCPEGYHD---PTCLSEVNEC--NSNPCVHGACRDS 733
DECA P G G C++ F C CP G+ +V+EC + PC +G C ++
Sbjct: 675 DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT 734
Query: 734 LNGYKCDC----DPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC-TCREG--FSGP 786
++C C P +G+ C+ + +ECE++ G C + + C TC G
Sbjct: 735 EGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 793
Query: 787 NCQTNINECASN--PCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNG-- 841
C T+++EC+S PC G C + ++C+C Y + PCA + C G
Sbjct: 794 RC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP--GPCADVNECLEGDF 850
Query: 842 ----GECRQSEDYESFSCVCPTGW----QGQTCEVDINECVLSPCRHGASCQNTHGGYRC 893
GEC ++ SF+C C G+ +G +C +D++EC C NT G + C
Sbjct: 851 CFPHGECLNTDG--SFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFEC 907
Query: 894 HCQAGYSG----RNCETDIDDCRPNPCHNGGS--CTDGINTAFC--DCLPGF----RGTF 941
C G+ +C D+D+CR GS C + + C DC PG+ GT
Sbjct: 908 ICPPGHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 966
Query: 942 CEEDINECAS-DPCRNGA-NCTDCVDSYTCT--CPAGFS---GIHCENNTPDCTESSCFN 994
+D++EC P GA C + SY CT C G+ G C++ S C
Sbjct: 967 --DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGA 1024
Query: 995 GGTCVDGINSFTCLCPPGFTGS----YCQHDVNECDS-QPCLHGGTCQDGCGSYRCTCPQ 1049
C + SF CLC G+ G+ +C DVNEC++ Q C++ GS+ C CP
Sbjct: 1025 HAVCQNLPGSFQCLCDQGYEGARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCPN 1083
Query: 1050 GYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP-SGWTGLYCDVPSVSCEVAAQRQ 1108
+ + C G T + + P S P + + RQ
Sbjct: 1084 --SPEEFDPMTGRCVPPRTSAG-----TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQ 1136
Query: 1109 GV--DVARLCQHGGLCVDAGNT--------HHCRCQAGY-TGSYCEDLVDECSPSPCQNG 1157
G R C DA + C C G GS C + +C +
Sbjct: 1137 GPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR--IQQCPGTETAEY 1194
Query: 1158 ATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ--NGGTCLDLPNTYKCSCPRG--- 1212
+ + GY +A ++ ++DEC Q G C++ Y C C G
Sbjct: 1195 QSLCPHGRGY----LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY 1250
Query: 1213 -TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNEC 1271
TQ + C I+ D+C P C G CV+ VG Y CTC P V +G C
Sbjct: 1251 HTQRLEC-IDNDEC------ADEEPAC-EGGRCVNTVGSYHCTCEPPLV---LDGSQRRC 1299
Query: 1272 LSN 1274
+SN
Sbjct: 1300 VSN 1302
Score = 236 bits (603), Expect = 2e-61
Identities = 259/912 (28%), Positives = 347/912 (38%), Gaps = 206/912 (22%)
Query: 35 GKCEAANGTEACVCGGAF-VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGF 93
G+CE + G+ CVCG F GPR + C + CH V C LG
Sbjct: 564 GRCENSPGSFRCVCGPGFRAGPRAAE--------CLDVDECHRVPP--------PCDLG- 606
Query: 94 SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSCQQADPCASNPC 149
C N T + C CP G+ G SCQ D C +P
Sbjct: 607 ----------------RCEN-------TPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG 643
Query: 150 ANG-GQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
G G C S+ C CP F G C +DV+EC Q+P C G C N GS+ C C A
Sbjct: 644 LCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPA 702
Query: 209 THTGPNCERPYVPC--------SPSPCQNGGTCRPTGDVTHECACLPGF----TGQNCEE 256
G P PC SP PC G C T + + +C C GF G CE+
Sbjct: 703 ---GFRSRGPGAPCQDVDECARSPPPC-TYGRCENT-EGSFQCVCPMGFQPNTAGSECED 757
Query: 257 NIDDCPGNNCKNGGACVDGVNTYNCR-CPPEWTGQY-----CTEDVDECQLMPNACQNGG 310
+D+C + G CV+ ++ CR CP +G + CT DVDEC C G
Sbjct: 758 -VDECENHLACPGQECVNSPGSFQCRTCP---SGHHLHRGRCT-DVDECSSGAPPCGPHG 812
Query: 311 TCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLC 370
C NT G + C C G+ P GR G
Sbjct: 813 HCTNTEGSFRCSCAPGY--------------------------------RAPSGRPGPCA 840
Query: 371 HLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY-TGP--ACSQDVDECSLGANPCEHAG 427
+N+ + C C +G CTC GY GP A DVDECS + C+ +G
Sbjct: 841 DVNECLEGDFCFPHGECLN--TDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQ-SG 896
Query: 428 KCINTLGSFECQCLQGY-TGPRCE--IDVNECVSN--PCQNDATCLDQIGEFQCI--CMP 480
C NT GSFEC C G+ GP +DV+EC C + G ++C+ C P
Sbjct: 897 ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDP 956
Query: 481 GY----EGVHCEVNTDECAS-SPCLHNG-RCLDKINEFQC--ECPTGF---TGHLCQYDV 529
GY EG C+ + DEC P + RC + ++C C G+ G CQ DV
Sbjct: 957 GYHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DV 1013
Query: 530 DECASTP-CKNGAKCLDGPNTYTCVCTEGYTGT----HCEVDIDECD--PDPCHYGSCKD 582
DEC + C A C + P ++ C+C +GY G HC VD++EC+ C C++
Sbjct: 1014 DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCEN 1072
Query: 583 GVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGP------ 636
+F C+C + + C G + A L P
Sbjct: 1073 VEGSFLCVC--PNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRR 1130
Query: 637 ------------NCEINLDDCASSPCDSGTCLDKIDGYECACEPGY-TGSMCNINIDECA 683
E D A CD+ + EC C G GS C I +C
Sbjct: 1131 PSTPRQGPVGSGRRECYFDTAAPDACDN-ILARNVTWQECCCTVGEGWGSGC--RIQQCP 1187
Query: 684 G-NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC---NSNPCVHGACRDSLNGYKC 739
G C G G+ P G D + +V+EC C G C ++ GY C
Sbjct: 1188 GTETAEYQSLCPHG-RGYL--APSG--DLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1242
Query: 740 DCDPGW----SGTNCDINNNEC-ESNPCVNGGTCKDMTSGYVCTCREGF----SGPNCQT 790
C G+ C I+N+EC + P GG C + Y CTC S C +
Sbjct: 1243 YCSNGYYYHTQRLEC-IDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1301
Query: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLP-------YTGATC---EVVLAPCAPSPCRN 840
N ++ + N G C +V G C P YT C E CA P ++
Sbjct: 1302 NESQSLDD---NLGVCWQEV-GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQD 1357
Query: 841 GGECRQSEDYES 852
S+D+E+
Sbjct: 1358 ------SDDFEA 1363
Score = 228 bits (582), Expect = 4e-59
Identities = 200/625 (32%), Positives = 270/625 (43%), Gaps = 110/625 (17%)
Query: 743 PGWSGTNCDIN---NNECESNPCVNG-GTCKDMTSGYVCTCREGF----SGPNCQTNINE 794
P W+G + + C+ NP V G G C SGY C C GF G C +++E
Sbjct: 495 PAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDE 553
Query: 795 C--ASNPCLNQGTCIDDVAGYKCNC-----LLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
C PC G C + ++C C P +V P PC + G C +
Sbjct: 554 CRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPC-DLGRCENT 611
Query: 848 EDYESFSCVCPTGWQ----GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSG 901
SF CVCP G+Q G +C+ D++EC SP C GA C+N G +RC C AG+ G
Sbjct: 612 PG--SFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRG 667
Query: 902 RNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASD--P 953
CE D+D+C P PC G C + + C C GFR G C +D++ECA P
Sbjct: 668 SACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPP 725
Query: 954 CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTC-L 1008
C G C + S+ C CP GF +G CE + +C G CV+ SF C
Sbjct: 726 CTYG-RCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRT 783
Query: 1009 CPPG--FTGSYCQHDVNECDS--QPCLHGGTCQDGCGSYRCTCPQGYTGPN-----CQNL 1059
CP G C DV+EC S PC G C + GS+RC+C GY P+ C ++
Sbjct: 784 CPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 842
Query: 1060 VHWCDSSPCKNGGKCWQTHTQYRCECPSGW----TGLYC-DVPSVSCEVAAQRQGVDVAR 1114
+ C G+C T + C C G+ G C DV S E
Sbjct: 843 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE-----------D 891
Query: 1115 LCQHGGLCVDAGNTHHCRCQAGYTG----SYCEDLVDEC---SPSPCQNGATCTDYLGGY 1167
LCQ G+C + + C C G+ + C D VDEC P+ C C + G Y
Sbjct: 892 LCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD-VDECRERGPALC-GSQRCENSPGSY 948
Query: 1168 SC--KCVAGYHG--VNCSEEIDECLSHPCQNGGT--CLDLPNTYKC--SCPRG---TQGV 1216
C C GYH +++DEC + + G C + P +Y+C +C G T G
Sbjct: 949 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1008
Query: 1217 HCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG----DVNEC- 1271
C+ +VD+C +RS C + C + G + C C G+ G R +G DVNEC
Sbjct: 1009 GCQ-DVDECR------NRS-FCGAHAVCQNLPGSFQCLCDQGYEGAR-DGRHCVDVNECE 1059
Query: 1272 -LSNPCDARGTQNCVQRVNDFHCEC 1295
L C G C F C C
Sbjct: 1060 TLQGVC---GAALCENVEGSFLCVC 1081
Score = 227 bits (578), Expect = 1e-58
Identities = 225/808 (27%), Positives = 318/808 (39%), Gaps = 164/808 (20%)
Query: 645 CASSP--CDSGTCLDKIDGYECACEPGYT----GSMCNINIDEC--AGNPCHNGGTCEDG 696
C +P C G C+ + GY CAC+ G+ G+ C I++DEC PC G CE+
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENS 569
Query: 697 INGFTCRCPEGYHD----PTCLSEVNECNS--NPCVHGACRDSLNGYKCDCDPGWS---- 746
F C C G+ CL +V+EC+ PC G C ++ + C C G+
Sbjct: 570 PGSFRCVCGPGFRAGPRAAECL-DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPH 628
Query: 747 GTNCDINNNECESNPCVNG-GTCKDMTSGYVCTCREGFSGPNCQTNINECASNPC-LNQG 804
G +C + +EC +P + G G CK++ + C C GF G C+ +++ECA P G
Sbjct: 629 GASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG 687
Query: 805 TCIDDVAGYKCNCLLPYT----GATCEVVLAPCA--PSPCRNGGECRQSEDYESFSCVCP 858
C + + C C + GA C+ V CA P PC G C +E SF CVCP
Sbjct: 688 RCDNTAGSFHCACPAGFRSRGPGAPCQDV-DECARSPPPCTYG-RCENTEG--SFQCVCP 743
Query: 859 TGWQ----GQTCEVDINECVLSPCRHGASCQNTHGGYRCH-CQAGYS-GRNCETDIDDCR 912
G+Q G CE D++EC G C N+ G ++C C +G+ R TD+D+C
Sbjct: 744 MGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECS 802
Query: 913 PN--PCHNGGSCTDGINTAFCDCLPGFRGTFCEE----DINECAS-DPCRNGANCTDCVD 965
PC G CT+ + C C PG+R D+NEC D C C +
Sbjct: 803 SGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG 862
Query: 966 SYTCTCPAGFS----GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTG----SY 1017
S+ CTC G+ G C + +C+E G C + SF C+CPPG +
Sbjct: 863 SFACTCAPGYRPGPRGASCLD-VDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLAS 921
Query: 1018 CQHDVNEC------------------------DSQPCLHGGT------------------ 1035
C DV+EC D P H G
Sbjct: 922 CL-DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC 980
Query: 1036 ----CQDGCGSYRCT--CPQGYT---GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP 1086
C++ GSYRCT C GY G CQ++ + S C C ++C C
Sbjct: 981 GAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCD 1040
Query: 1087 SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH---GGLCVDAGN-------THHC---RC 1133
G+ G V QGV A LC++ LCV + T C R
Sbjct: 1041 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT 1100
Query: 1134 QAG-YTGSYCEDLVDECSPS-------PCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI- 1184
AG + GS + P+ P + +G +C + + I
Sbjct: 1101 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNIL 1160
Query: 1185 ------DECLSHPCQNGGTCLDL---PNT----YKCSCPRG------TQGVHCEINVDDC 1225
EC + G+ + P T Y+ CP G + + +VD+C
Sbjct: 1161 ARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1220
Query: 1226 NPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV--GERCEG-DVNECLSNPCDARGTQ 1282
D V +S G CV+ GYSC C G+ +R E D +EC G +
Sbjct: 1221 QLFRDQVCKS------GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1274
Query: 1283 NCVQRVNDFHCECR----AGHTGRRCES 1306
CV V +HC C + RRC S
Sbjct: 1275 -CVNTVGSYHCTCEPPLVLDGSQRRCVS 1301
Score = 209 bits (532), Expect = 3e-53
Identities = 187/625 (29%), Positives = 256/625 (40%), Gaps = 138/625 (22%)
Query: 884 CQNTHGGYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGF 937
C + GY C C +G+ G C D+D+CR P PC G C + + C C PGF
Sbjct: 524 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGF 581
Query: 938 R-GTFCEE--DINEC--ASDPCRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCT 988
R G E D++EC PC G C + S+ C CPAG+ G C++ +CT
Sbjct: 582 RAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD-VDECT 639
Query: 989 ESSCFNG-GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSYRCT 1046
+S G G C + SF C+CP GF GS C+ DV+EC +P G G C + GS+ C
Sbjct: 640 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA 699
Query: 1047 CPQGY----TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE 1102
CP G+ G CQ++ S P G+C T ++C CP G+ + CE
Sbjct: 700 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP---NTAGSECE 756
Query: 1103 VAAQRQGVDVARLCQHGGLCVDAGNTHHCR-CQAGY--TGSYCEDLVDECSPS--PCQNG 1157
+ + L G CV++ + CR C +G+ C D VDECS PC
Sbjct: 757 DVDECEN----HLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTD-VDECSSGAPPCGPH 811
Query: 1158 ATCTDYLGGYSCKCVAGYHGVN-----CSEEIDECLSHP-CQNGGTCLDLPNTYKCSCP- 1210
CT+ G + C C GY + C+ +++ECL C G CL+ ++ C+C
Sbjct: 812 GHCTNTEGSFRCSCAPGYRAPSGRPGPCA-DVNECLEGDFCFPHGECLNTDGSFACTCAP 870
Query: 1211 ---RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGD 1267
G +G C ++VD+C S C +G C + G + C CPP G R D
Sbjct: 871 GYRPGPRGASC-LDVDEC-------SEEDLC-QSGICTNTDGSFECICPP---GHRAGPD 918
Query: 1268 VNECLS-NPCDAR-----GTQNCVQRVNDFHC--ECRAG-HTG----------------- 1301
+ CL + C R G+Q C + C +C G H G
Sbjct: 919 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 978
Query: 1302 ----RRCESVINGCKGKP-------------------CKNGGTC---AVASNTARGFICK 1335
+RCE+ + P C+N C AV N F C
Sbjct: 979 ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1038
Query: 1336 CPAGFEGA----------TCENDARTCGSLRCLN--GGTCISGPRSP------TCLCL-- 1375
C G+EGA CE CG+ C N G P SP T C+
Sbjct: 1039 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1098
Query: 1376 ----GPFTGPECQFPASSPCLGGNP 1396
G F G + Q PA SP L P
Sbjct: 1099 RTSAGTFPGSQPQAPA-SPVLPARP 1122
Score = 163 bits (412), Expect = 2e-39
Identities = 230/872 (26%), Positives = 330/872 (37%), Gaps = 151/872 (17%)
Query: 779 CREGFSGPN--CQTNINECASNPCLNQGTCIDDVAGYKCNC----LLPYTGATC--EVVL 830
C GF N C+ +++ECA+ G C + GY C C LL + ++C + V+
Sbjct: 307 CPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 365
Query: 831 APCAPSPC----RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQN 886
+ A PC R+GG C +C G+ C L P G+
Sbjct: 366 SE-AKGPCFRVLRDGG-CSLPILRNITKQICCCSRVGKAWG---RGCQLCP-PFGSE--- 416
Query: 887 THGGYRCHCQAGYSGRNCETDID-DCRPNPCHNGGSCTDGINTAFCDCLP--GFRGTFCE 943
G+R C AG +D+ + RP T P GF T
Sbjct: 417 ---GFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRL 473
Query: 944 EDINECASDPCRNGANCTDCVDSYTCT--CPAGFSGIHCENNTPDCTESSCFNGGTCVDG 1001
E E DP + ++T +G S C+ N C G C+
Sbjct: 474 EPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC------GPGRCISR 527
Query: 1002 INSFTCLCPPGFT----GSYCQHDVNECDS--QPCLHGGTCQDGCGSYRCTCPQGY-TGP 1054
+ +TC C GF G+ C DV+EC PC G C++ GS+RC C G+ GP
Sbjct: 528 PSGYTCACDSGFRLSPQGTRCI-DVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGP 585
Query: 1055 N---CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVD 1111
C ++ P + G+C T + C CP+G+ + Q G
Sbjct: 586 RAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG-- 643
Query: 1112 VARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSC 1169
LC G C + + C C AG+ GS CE+ VDEC+ P PC G C + G + C
Sbjct: 644 ---LCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR-CDNTAGSFHC 698
Query: 1170 KCVAGYH----GVNCSEEIDECL-SHPCQNGGTCLDLPNTYKCSCPRG----TQGVHCEI 1220
C AG+ G C +++DEC S P G C + +++C CP G T G CE
Sbjct: 699 ACPAGFRSRGPGAPC-QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE- 756
Query: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC-TCPPG--FVGERCEGDVNECLSN--P 1275
+VD+C + + CV+ G + C TCP G RC DV+EC S P
Sbjct: 757 DVDECENHLACPGQE--------CVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSGAPP 807
Query: 1276 CDARGTQNCVQRVNDFHCECRAGH---TGRR--CESVINGCKGKPCKNGGTCAVASNTAR 1330
C G +C F C C G+ +GR C V +G C G C NT
Sbjct: 808 CGPHG--HCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECL---NTDG 862
Query: 1331 GFICKCPAGFE----GATCENDARTCGSLRCLNGGTCISGPRSPTCLCL-GPFTGPECQF 1385
F C C G+ GA+C D C G C + S C+C G GP+
Sbjct: 863 SFACTCAPGYRPGPRGASCL-DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL-- 919
Query: 1386 PASSPCLGGNPCYNQGT-------CEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGR 1438
+ CL + C +G CE + S YRC + D G AG
Sbjct: 920 ---ASCLDVDECRERGPALCGSQRCENSPGS--YRC------------VRDCDPGYHAGP 962
Query: 1439 DIPPPLIEEA-------CELPECQEDAGNKVCSLQCNNHACGWDGGDCS----------L 1481
+ ++E C C+ G+ C+ C+ GG C
Sbjct: 963 EGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFC 1022
Query: 1482 NFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFS 1541
+ +N S QC D + + C+ D +C+ +G C C++
Sbjct: 1023 GAHAVCQNLPGSFQC---LCDQGYEGARDGRHCV-DVNECETLQGVCGA---ALCENVEG 1075
Query: 1542 DGHCDQGCNSAECEWDGLDCAEHVPERLAAGT 1573
C C ++ E+D + VP R +AGT
Sbjct: 1076 SFLC--VCPNSPEEFDPM-TGRCVPPRTSAGT 1104
Score = 125 bits (313), Expect = 7e-28
Identities = 142/531 (26%), Positives = 187/531 (35%), Gaps = 117/531 (22%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPR-----CQDPNPCLSTP-CKNAGTCHVV 77
CS C G C G+ C C + P C D N CL C G C
Sbjct: 801 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNT 860
Query: 78 DRRGVADYACSCALGF-SGPLCLTPLD-NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSG 135
D +AC+CA G+ GP + LD + C G C T ++C CPPG
Sbjct: 861 D----GSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC-TNTDGSFECICPPGHRA 915
Query: 136 ----KSCQQADPCAS-NPCANGGQ-CLPFEASYIC--HCPPSFH-GP--TCRQDVNECGQ 184
SC D C P G Q C SY C C P +H GP TC DV+EC +
Sbjct: 916 GPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC-DDVDECQE 974
Query: 185 -KPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHEC 243
P +C C N GSYRC P C+ Y P CQ+ CR
Sbjct: 975 YGPEIC-GAQRCENTPGSYRCT-------PACDPGYQPTPGGGCQDVDECRNRSFCGAHA 1026
Query: 244 AC--LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQL 301
C LPG C++ + ++G CV DV+EC+
Sbjct: 1027 VCQNLPGSFQCLCDQGYE-----GARDGRHCV---------------------DVNECET 1060
Query: 302 MPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC----ASAACFHGATCH------ 351
+ C C N G + CVC N + E+ C SA F G+
Sbjct: 1061 LQGVC-GAALCENVEGSFLCVCPN--SPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPV 1117
Query: 352 ----------DRVASFYCECPHGRTGLLCHLNDA------------------CISNPCNE 383
R S + P G C+ + A C +
Sbjct: 1118 LPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW 1177
Query: 384 GSNC------DTNPVNGKAICTCPSGYTGP----ACSQDVDECSLGANPCEHAGKCINTL 433
GS C T +++C GY P + +DVDEC L + +G C+NT
Sbjct: 1178 GSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTA 1237
Query: 434 GSFECQCLQG--YTGPRCE-IDVNECV-SNPCQNDATCLDQIGEFQCICMP 480
+ C C G Y R E ID +EC P C++ +G + C C P
Sbjct: 1238 PGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Score = 52.8 bits (125), Expect = 4e-06
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 11/83 (13%)
Query: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNEC----VSNPCQN 463
+ +EC + + C + G+C+ F C+C GY T C +D+NEC ++P
Sbjct: 1496 EAEECGI-LDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1552
Query: 464 DATCLDQIGEFQCICMPGYEGVH 486
+A CL+ G F+CIC PG+ H
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPTH 1575
Score = 49.7 bits (117), Expect = 4e-05
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 526 QYDVDECASTP-CKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPDP-----C 575
+ + +EC C NG +C+ P +TC C +GY T C VDI+ECD C
Sbjct: 1494 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLC 1551
Query: 576 HYGSCKDGVATFTCLCRPGYT----GHHC 600
C + +F C+CRPG+ HHC
Sbjct: 1552 VNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 7/82 (8%)
Query: 488 EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQY---DVDEC----ASTPCKNG 540
E+ +EC NGRC+ F C C G+ + + D++EC A++P
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 541 AKCLDGPNTYTCVCTEGYTGTH 562
A+CL+ ++ C+C G+ TH
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTH 1575
Score = 47.0 bits (110), Expect = 2e-04
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 12/92 (13%)
Query: 670 YTGSMCN----INIDECAGNPCHNGGTCEDGINGFTCRCPEGYH-DPTCLS--EVNECN- 721
Y GS+ + +EC G C GFTCRC +GY D T ++ ++NEC+
Sbjct: 1484 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDE 1543
Query: 722 ----SNPCVHGACRDSLNGYKCDCDPGWSGTN 749
S CV+ C ++ ++C C PG++ T+
Sbjct: 1544 AEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1575
Score = 40.4 bits (93), Expect = 0.023
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 10/70 (14%)
Query: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCE---VDINEC----VLSPCRHGASCQNTHGG 890
C NG R E F+C C G++ VDINEC SP A C NT G
Sbjct: 1506 CTNGRCVRVPE---GFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1562
Query: 891 YRCHCQAGYS 900
+RC C+ G++
Sbjct: 1563 FRCICRPGFA 1572
Score = 39.7 bits (91), Expect = 0.038
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 1183 EIDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1241
E +EC + C NG C+ +P + C C G + + D N + + SP C N
Sbjct: 1496 EAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN- 1553
Query: 1242 GTCVDQVGGYSCTCPPGF 1259
C++ G + C C PGF
Sbjct: 1554 ARCLNTDGSFRCICRPGF 1571
Score = 38.5 bits (88), Expect = 0.086
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 10/68 (14%)
Query: 992 CFNGGTCVDGINSFTCLCPPGF----TGSYCQHDVNECD----SQPCLHGGTCQDGCGSY 1043
C NG CV FTC C G+ T C D+NECD + P C + GS+
Sbjct: 1506 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACV-DINECDEAEAASPLCVNARCLNTDGSF 1563
Query: 1044 RCTCPQGY 1051
RC C G+
Sbjct: 1564 RCICRPGF 1571
Score = 38.1 bits (87), Expect = 0.11
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 11/86 (12%)
Query: 140 QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQ---DVNECGQKPG---LCRHGG 193
+A+ C G+C+ + C C + R D+NEC + LC +
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA- 1554
Query: 194 TCHNEVGSYRCVCR----ATHTGPNC 215
C N GS+RC+CR TH +C
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 37.4 bits (85), Expect = 0.19
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 21/92 (22%)
Query: 943 EEDINECAS-DPCRNGANCTDCVDSYTCTCPAGF----SGIHC---------ENNTPDCT 988
E + EC D C NG C + +TC C G+ + + C E +P C
Sbjct: 1494 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1552
Query: 989 ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH 1020
+ C N DG SF C+C PGF ++ H
Sbjct: 1553 NARCLN----TDG--SFRCICRPGFAPTHQPH 1578
Score = 36.6 bits (83), Expect = 0.33
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 11/87 (12%)
Query: 636 PNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYTGSMCN---INIDEC----AGNPC 687
P E+ ++C C +G C+ +G+ C C GY M ++I+EC A +P
Sbjct: 1491 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1550
Query: 688 HNGGTCEDGINGFTCRCPEGY---HDP 711
C + F C C G+ H P
Sbjct: 1551 CVNARCLNTDGSFRCICRPGFAPTHQP 1577
Score = 33.9 bits (76), Expect = 2.1
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 12/79 (15%)
Query: 716 EVNECNS-NPCVHGACRDSLNGYKCDCDPGW----SGTNCDINNNECE-----SNPCVNG 765
E EC + C +G C G+ C C G+ + C ++ NEC+ S CVN
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNA 1554
Query: 766 GTCKDMTSGYVCTCREGFS 784
C + + C CR GF+
Sbjct: 1555 -RCLNTDGSFRCICRPGFA 1572
Score = 33.1 bits (74), Expect = 3.6
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 867 EVDINEC-VLSPCRHGASCQNTHGGYRCHCQAGY---SGRNCETDIDDC----RPNPCHN 918
E++ EC +L C +G C G+ C C GY R DI++C +P
Sbjct: 1494 ELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1552
Query: 919 GGSCTDGINTAFCDCLPGFRGT 940
C + + C C PGF T
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPT 1574
Score = 33.1 bits (74), Expect = 3.6
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 8/70 (11%)
Query: 264 NNCKNGGACVDGVNTYNCRCPP----EWTGQYCTE--DVDECQLMPNACQNGGTCHNTHG 317
+ C NG CV + CRC + T C + + DE + C N C NT G
Sbjct: 1504 DGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA-RCLNTDG 1561
Query: 318 GYNCVCVNGW 327
+ C+C G+
Sbjct: 1562 SFRCICRPGF 1571
Score = 32.3 bits (72), Expect = 6.1
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 14/107 (13%)
Query: 1242 GTCVDQVGGYSCTCP-PGFVGER--CEG-----DVNECLSNPCDARGTQNCVQRVNDFHC 1293
G C ++ G C P PG + C G V++C C R + D C
Sbjct: 250 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDC--QLCSERLGNSERVSAPDGPC 307
Query: 1294 ECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1340
CE V G C++G CA NT G+ C CP GF
Sbjct: 308 PTGFERVNGSCEDVDECATGGRCQHG-ECA---NTRGGYTCVCPDGF 350
Score = 32.0 bits (71), Expect = 8.0
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 15/94 (15%)
Query: 1137 YTGSYCEDL----VDECSP-SPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDEC 1187
Y GS E +EC C NG C G++C+C GY + C +I+EC
Sbjct: 1484 YAGSLAEPYEELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMAC-VDINEC 1541
Query: 1188 ----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
+ P CL+ +++C C G H
Sbjct: 1542 DEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1575
Score = 32.0 bits (71), Expect = 8.0
Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ---TNINEC----ASNPCLNQ 803
++ EC G C + G+ C C +G+ + +INEC A++P
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 804 GTCIDDVAGYKCNC 817
C++ ++C C
Sbjct: 1554 ARCLNTDGSFRCIC 1567
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 269 bits (687), Expect = 3e-71
Identities = 339/1278 (26%), Positives = 475/1278 (37%), Gaps = 290/1278 (22%)
Query: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ----ADPCA-----------SNPCAN---- 151
C NGG C + +C CPP ++GK CQ A P A + P AN
Sbjct: 157 CHNGGVC----VKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDD 212
Query: 152 --GGQCL-------PFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSY 202
G + P EAS + H GP D + R V +
Sbjct: 213 EHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQ 272
Query: 203 RC-------------VCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV--THECACLP 247
C G C P P CR G H+C
Sbjct: 273 SAPREDGYSDASGFGYCFRELRGGECASPL----PGLRTQEVCCRGAGLAWGVHDC---- 324
Query: 248 GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
Q C E + + + +G C G N C EDVDEC CQ
Sbjct: 325 ----QLCSERLGNSERVSAPDG-PCPTGFERVNGSC----------EDVDECAT-GGRCQ 368
Query: 308 NGGTCHNTHGGYNCVCVNGW----TGEDC-SENIDDCASAACFHGATCHDRVASFYCECP 362
+G C NT GGY CVC +G+ + C S+++ A CF + C P
Sbjct: 369 HG-ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR------VLRDGGCSLP 421
Query: 363 HGR--TGLLCHLNDACISNPCNEGSNCDTNPVNG----KAICTCPSGYTGPACSQDVDEC 416
R T +C C G C P G + IC GY A +
Sbjct: 422 ILRNITKQIC----CCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTR 477
Query: 417 SLGANPCEHAGKCINTLGS-----------------------------FECQCLQGYTGP 447
LG P + TL + + +TGP
Sbjct: 478 PLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGP 537
Query: 448 RCEIDVNECVSNPCQND------ATCLDQIGEFQCICMPGY----EGVHCEVNTDEC--A 495
EI + S CQ + C+ + + C C G+ +G C ++ DEC
Sbjct: 538 --EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 594
Query: 496 SSPCLHNGRCLDKINEFQCECPTGF----TGHLCQYDVDEC--ASTPCKNGAKCLDGPNT 549
PC GRC + F+C C GF C DVDEC PC G +C + P +
Sbjct: 595 PPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGS 651
Query: 550 YTCVCTEGYT----GTHCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGHHCETN 603
+ CVC GY G C+ D+DEC P C G+CK+ +F C+C G+ G CE +
Sbjct: 652 FLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 710
Query: 604 INECSSQPCRHG-GTCQDRDNAYLCFCLKG--TTGPN--CEINLDDCASS--PCDSGTCL 656
++EC+ +P G G C + ++ C C G + GP C+ ++D+CA S PC G C
Sbjct: 711 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCE 769
Query: 657 DKIDGYECAC----EPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR-CPEGYH-D 710
+ ++C C +P GS C ++DEC + G C + F CR CP G+H
Sbjct: 770 NTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH 828
Query: 711 PTCLSEVNECNSN--PC-VHGACRDSLNGYKCDCDPGW------SGTNCDINNNEC-ESN 760
++V+EC+S PC HG C ++ ++C C PG+ G D+ NEC E +
Sbjct: 829 RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV--NECLEGD 886
Query: 761 PCVNGGTCKDMTSGYVCTCREGF----SGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
C G C + + CTC G+ G +C +++EC+ G C + ++C
Sbjct: 887 FCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECI 945
Query: 817 CLLPYTGATCEVVLAPCAP-SPCRNGGEC-----RQSEDYESFSCV--CPTGWQG---QT 865
C G LA C CR G R S+ CV C G+ T
Sbjct: 946 C---PPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 1002
Query: 866 CEVDINEC-VLSPCRHGAS-CQNTHGGYRC--HCQAGYS---GRNCETDIDDCRPNP-CH 917
C+ D++EC P GA C+NT G YRC C GY G C+ D+D+CR C
Sbjct: 1003 CD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCG 1060
Query: 918 NGGSCTDGINTAFCDCLPGFRGT----FCEEDINECAS-DPCRNGANCTDCVDSYTCTCP 972
C + + C C G+ G C D+NEC + A C + S+ C CP
Sbjct: 1061 AHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1119
Query: 973 AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL- 1031
N+P+ + G CV PP + + + P L
Sbjct: 1120 ----------NSPEEFDPMT---GRCV----------PPRTSAGTFPGSQPQAPASPVLP 1156
Query: 1032 ----------HGGTCQDG-CGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ 1080
T + G GS R C P+ CD+ +N WQ +
Sbjct: 1157 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDA------CDNILARN--VTWQ---E 1205
Query: 1081 YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG-GLCVDAGNTHHCRCQAGYTG 1139
C GW G C + A+ Q LC HG G +G+ R
Sbjct: 1206 CCCTVGEGW-GSGCRIQQCPGTETAEYQS-----LCPHGRGYLAPSGDLSLRRD------ 1253
Query: 1140 SYCEDLVDECS---PSPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDECL-SHP 1191
VDEC C++G C + GYSC C GY+ + C + DEC P
Sbjct: 1254 ------VDECQLFRDQVCKSG-VCVNTAPGYSCYCSNGYYYHTQRLECIDN-DECADEEP 1305
Query: 1192 CQNGGTCLDLPNTYKCSC 1209
GG C++ +Y C+C
Sbjct: 1306 ACEGGRCVNTVGSYHCTC 1323
Score = 259 bits (661), Expect = 3e-68
Identities = 240/860 (27%), Positives = 336/860 (39%), Gaps = 161/860 (18%)
Query: 131 PGWSGKSCQQADP----CASNPCANG-GQCLPFEASYICHCPPSFH----GPTCRQDVNE 181
P W+G ++ P C NP G G+C+ + Y C C F G C DV+E
Sbjct: 532 PAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCI-DVDE 590
Query: 182 CGQKPGLCRHGGTCHNEVGSYRCVCR-ATHTGPN---------CERPYVPCSPSPCQNGG 231
C + P C G C N GS+RCVC GP C R PC C+N
Sbjct: 591 CRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP 649
Query: 232 TCRPTGDVTHECACLPGFT----GQNCEENIDDCPGNNCKNG-GACVDGVNTYNCRCPPE 286
+ C C G+ G +C++ +D+C + G GAC + ++ C CP
Sbjct: 650 G-------SFLCVCPAGYQAAPHGASCQD-VDECTQSPGLCGRGACKNLPGSFRCVCPAG 701
Query: 287 WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT----GEDCSENIDDCASA 342
+ G C EDVDEC P C G C NT G ++C C G+ G C +++D+CA +
Sbjct: 702 FRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARS 759
Query: 343 A--CFHGATCHDRVASFYCECPHG----RTGLLCHLNDACISNPCNEGSNCDTNPVNGKA 396
C +G C + SF C CP G G C D C ++ G C +P G
Sbjct: 760 PPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP--GSF 816
Query: 397 IC-TCPSGYT--GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE--- 450
C TCPSG+ C+ DVDECS GA PC G C NT GSF C C GY P
Sbjct: 817 QCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 875
Query: 451 -IDVNECVSNP-CQNDATCLDQIGEFQCICMPGY----EGVHCEVNTDECASSPCLHNGR 504
DVNEC+ C CL+ G F C C PGY G C ++ DEC+ +G
Sbjct: 876 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 934
Query: 505 CLDKINEFQCECPTGFTGH---LCQYDVDECAST-PCKNGA-KCLDGPNTYTCV--CTEG 557
C + F+C CP G DVDEC P G+ +C + P +Y CV C G
Sbjct: 935 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 994
Query: 558 Y----TGTHCEVDIDECD---PDPCHYGSCKDGVATFTC--LCRPGY---TGHHCETNIN 605
Y GT C+ D+DEC P+ C C++ ++ C C PGY G C+ +++
Sbjct: 995 YHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVD 1051
Query: 606 ECSSQP-CRHGGTCQDRDNAYLCFCLKGTTGPN-----CEINLDDCASSPCDSGTCLDKI 659
EC ++ C CQ+ ++ C C +G G ++N + C + C +
Sbjct: 1052 ECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVE 1111
Query: 660 DGYECAC--EPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF---------TCRCPEGY 708
+ C C P M + G + + R P
Sbjct: 1112 GSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTP 1171
Query: 709 HDPTCLSEVNECNSNPCVHGACRD----SLNGYKCDC--DPGWSGTNCDINNNECESNPC 762
S EC + AC + ++ +C C GW G+ C I C
Sbjct: 1172 RQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRIQQ-------C 1223
Query: 763 VNGGTCKDMTSGYVCTCREGFSGP----NCQTNINECA--SNPCLNQGTCIDDVAGYKCN 816
T + + +C G+ P + + +++EC + G C++ GY C
Sbjct: 1224 PGTETAEYQS---LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1280
Query: 817 CLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLS 876
C Y T + C + EC E
Sbjct: 1281 CSNGYYYHTQRL--------ECIDNDECADEE---------------------------- 1304
Query: 877 PCRHGASCQNTHGGYRCHCQ 896
P G C NT G Y C C+
Sbjct: 1305 PACEGGRCVNTVGSYHCTCE 1324
Score = 256 bits (653), Expect = 3e-67
Identities = 251/868 (28%), Positives = 346/868 (39%), Gaps = 160/868 (18%)
Query: 324 VNGWTGED----------CSENIDDCASAACFHGATCHDRVASFYCECPHG----RTGLL 369
+ WTG + C N C C R + + C C G G
Sbjct: 531 IPAWTGPEIPESGPSSGMCQRNPQVCGPGRCI------SRPSGYTCACDSGFRLSPQGTR 584
Query: 370 CHLNDAC--ISNPCNEGSNCDTNPVNGKAICTCPSGY-TGPACSQ--DVDECSLGANPCE 424
C D C + PC G C+ +P G C C G+ GP ++ DVDEC PC+
Sbjct: 585 CIDVDECRRVPPPCAPG-RCENSP--GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCD 641
Query: 425 HAGKCINTLGSFECQCLQGYT----GPRCEIDVNECVSNP--CQNDATCLDQIGEFQCIC 478
G+C NT GSF C C GY G C+ DV+EC +P C A C + G F+C+C
Sbjct: 642 -LGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVC 698
Query: 479 MPGYEGVHCEVNTDECASSPC-LHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECA 533
G+ G CE + DECA P GRC + F C CP GF G CQ DVDECA
Sbjct: 699 PAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECA 757
Query: 534 STP--CKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPD-PCHYGSCKDGVAT 586
+P C G +C + ++ CVC G+ G+ CE D+DEC+ C C + +
Sbjct: 758 RSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGS 815
Query: 587 FTCLCRPGYTGHHCE----TNINECSS--QPCRHGGTCQDRDNAYLCFCL------KGTT 634
F C P +GHH T+++ECSS PC G C + + ++ C C G
Sbjct: 816 FQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 873
Query: 635 GPNCEINLDDCASSPC--DSGTCLDKIDGYECACEPGYT----GSMCNINIDECAGNPCH 688
GP ++N +C G CL+ + C C PGY G+ C +++DEC+
Sbjct: 874 GPCADVN--ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLC 930
Query: 689 NGGTCEDGINGFTCRCPEGYH---DPTCLSEVNECNSN-PCVHGA--CRDSLNGYKC--D 740
G C + F C CP G+ D +V+EC P + G+ C +S Y+C D
Sbjct: 931 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 990
Query: 741 CDPGW----SGTNCDINNNEC-ESNPCVNGGT-CKDMTSGYVCT--CREGFS---GPNCQ 789
CDPG+ GT D++ EC E P + G C++ Y CT C G+ G CQ
Sbjct: 991 CDPGYHAGPEGTCDDVD--ECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ 1048
Query: 790 TNINECASNP-CLNQGTCIDDVAGYKCNCLLPYTGAT----------CEVVLAPCAPSPC 838
+++EC + C C + ++C C Y GA CE + C + C
Sbjct: 1049 -DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALC 1107
Query: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAG 898
N SF CVCP + + CV P R A T G + A
Sbjct: 1108 ENVEG--------SFLCVCPNS--PEEFDPMTGRCV--PPRTSAG---TFPGSQPQAPAS 1152
Query: 899 Y------------------------SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCL 934
SGR E D P+ C N + C C
Sbjct: 1153 PVLPARPPPPPLPRRPSTPRQGPVGSGRR-ECYFDTAAPDACDN--ILARNVTWQECCCT 1209
Query: 935 PGFR-GTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCF 993
G G+ C I +C + C P+G + + +
Sbjct: 1210 VGEGWGSGCR--IQQCPGTETAEYQSL--CPHGRGYLAPSGDLSLRRDVDECQLFRDQVC 1265
Query: 994 NGGTCVDGINSFTCLCPPGF---TGSYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCTC-P 1048
G CV+ ++C C G+ T D +EC D +P GG C + GSY CTC P
Sbjct: 1266 KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Query: 1049 QGYTGPNCQNLVHWCDSSPCKNGGKCWQ 1076
+ + V S N G CWQ
Sbjct: 1326 PLVLDGSQRRCVSNESQSLDDNLGVCWQ 1353
Score = 256 bits (653), Expect = 3e-67
Identities = 234/843 (27%), Positives = 354/843 (41%), Gaps = 131/843 (15%)
Query: 518 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYT----GTHCEVDIDECD-- 571
+G + +CQ + C +C+ P+ YTC C G+ GT C +D+DEC
Sbjct: 542 SGPSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 594
Query: 572 PDPCHYGSCKDGVATFTCLCRPGYTGH----HCETNINECSS--QPCRHGGTCQDRDNAY 625
P PC G C++ +F C+C PG+ C +++EC PC G C++ ++
Sbjct: 595 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGSF 652
Query: 626 LCFCLKGTT----GPNCEINLDDCASSP--CDSGTCLDKIDGYECACEPGYTGSMCNINI 679
LC C G G +C+ ++D+C SP C G C + + C C G+ GS C ++
Sbjct: 653 LCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 711
Query: 680 DECAGNPCHNG-GTCEDGINGFTCRCPEGYHD---PTCLSEVNEC--NSNPCVHGACRDS 733
DECA P G G C++ F C CP G+ +V+EC + PC +G C ++
Sbjct: 712 DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT 771
Query: 734 LNGYKCDC----DPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC-TCREG--FSGP 786
++C C P +G+ C+ + +ECE++ G C + + C TC G
Sbjct: 772 EGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 830
Query: 787 NCQTNINECASN--PCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP-SPCRNG-- 841
C T+++EC+S PC G C + ++C+C Y + PCA + C G
Sbjct: 831 RC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP--GPCADVNECLEGDF 887
Query: 842 ----GECRQSEDYESFSCVCPTGW----QGQTCEVDINECVLSPCRHGASCQNTHGGYRC 893
GEC ++ SF+C C G+ +G +C +D++EC C NT G + C
Sbjct: 888 CFPHGECLNTDG--SFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFEC 944
Query: 894 HCQAGYSG----RNCETDIDDCRPNPCHNGGS--CTDGINTAFC--DCLPGF----RGTF 941
C G+ +C D+D+CR GS C + + C DC PG+ GT
Sbjct: 945 ICPPGHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 1003
Query: 942 CEEDINECAS-DPCRNGA-NCTDCVDSYTCT--CPAGFS---GIHCENNTPDCTESSCFN 994
+D++EC P GA C + SY CT C G+ G C++ S C
Sbjct: 1004 --DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGA 1061
Query: 995 GGTCVDGINSFTCLCPPGFTGS----YCQHDVNECDS-QPCLHGGTCQDGCGSYRCTCPQ 1049
C + SF CLC G+ G+ +C DVNEC++ Q C++ GS+ C CP
Sbjct: 1062 HAVCQNLPGSFQCLCDQGYEGARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCPN 1120
Query: 1050 GYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP-SGWTGLYCDVPSVSCEVAAQRQ 1108
+ + C G T + + P S P + + RQ
Sbjct: 1121 --SPEEFDPMTGRCVPPRTSAG-----TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQ 1173
Query: 1109 GV--DVARLCQHGGLCVDAGNT--------HHCRCQAGY-TGSYCEDLVDECSPSPCQNG 1157
G R C DA + C C G GS C + +C +
Sbjct: 1174 GPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR--IQQCPGTETAEY 1231
Query: 1158 ATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ--NGGTCLDLPNTYKCSCPRG--- 1212
+ + GY +A ++ ++DEC Q G C++ Y C C G
Sbjct: 1232 QSLCPHGRGY----LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY 1287
Query: 1213 -TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNEC 1271
TQ + C I+ D+C P C G CV+ VG Y CTC P V +G C
Sbjct: 1288 HTQRLEC-IDNDEC------ADEEPAC-EGGRCVNTVGSYHCTCEPPLV---LDGSQRRC 1336
Query: 1272 LSN 1274
+SN
Sbjct: 1337 VSN 1339
Score = 236 bits (603), Expect = 2e-61
Identities = 259/912 (28%), Positives = 347/912 (38%), Gaps = 206/912 (22%)
Query: 35 GKCEAANGTEACVCGGAF-VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGF 93
G+CE + G+ CVCG F GPR + C + CH V C LG
Sbjct: 601 GRCENSPGSFRCVCGPGFRAGPRAAE--------CLDVDECHRVPP--------PCDLG- 643
Query: 94 SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSCQQADPCASNPC 149
C N T + C CP G+ G SCQ D C +P
Sbjct: 644 ----------------RCEN-------TPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG 680
Query: 150 ANG-GQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRA 208
G G C S+ C CP F G C +DV+EC Q+P C G C N GS+ C C A
Sbjct: 681 LCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPA 739
Query: 209 THTGPNCERPYVPC--------SPSPCQNGGTCRPTGDVTHECACLPGF----TGQNCEE 256
G P PC SP PC G C T + + +C C GF G CE+
Sbjct: 740 ---GFRSRGPGAPCQDVDECARSPPPC-TYGRCENT-EGSFQCVCPMGFQPNTAGSECED 794
Query: 257 NIDDCPGNNCKNGGACVDGVNTYNCR-CPPEWTGQY-----CTEDVDECQLMPNACQNGG 310
+D+C + G CV+ ++ CR CP +G + CT DVDEC C G
Sbjct: 795 -VDECENHLACPGQECVNSPGSFQCRTCP---SGHHLHRGRCT-DVDECSSGAPPCGPHG 849
Query: 311 TCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLC 370
C NT G + C C G+ P GR G
Sbjct: 850 HCTNTEGSFRCSCAPGY--------------------------------RAPSGRPGPCA 877
Query: 371 HLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY-TGP--ACSQDVDECSLGANPCEHAG 427
+N+ + C C +G CTC GY GP A DVDECS + C+ +G
Sbjct: 878 DVNECLEGDFCFPHGECLN--TDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQ-SG 933
Query: 428 KCINTLGSFECQCLQGY-TGPRCE--IDVNECVSN--PCQNDATCLDQIGEFQCI--CMP 480
C NT GSFEC C G+ GP +DV+EC C + G ++C+ C P
Sbjct: 934 ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDP 993
Query: 481 GY----EGVHCEVNTDECAS-SPCLHNG-RCLDKINEFQC--ECPTGF---TGHLCQYDV 529
GY EG C+ + DEC P + RC + ++C C G+ G CQ DV
Sbjct: 994 GYHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DV 1050
Query: 530 DECASTP-CKNGAKCLDGPNTYTCVCTEGYTGT----HCEVDIDECD--PDPCHYGSCKD 582
DEC + C A C + P ++ C+C +GY G HC VD++EC+ C C++
Sbjct: 1051 DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCEN 1109
Query: 583 GVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGP------ 636
+F C+C + + C G + A L P
Sbjct: 1110 VEGSFLCVC--PNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRR 1167
Query: 637 ------------NCEINLDDCASSPCDSGTCLDKIDGYECACEPGY-TGSMCNINIDECA 683
E D A CD+ + EC C G GS C I +C
Sbjct: 1168 PSTPRQGPVGSGRRECYFDTAAPDACDN-ILARNVTWQECCCTVGEGWGSGC--RIQQCP 1224
Query: 684 G-NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC---NSNPCVHGACRDSLNGYKC 739
G C G G+ P G D + +V+EC C G C ++ GY C
Sbjct: 1225 GTETAEYQSLCPHG-RGYL--APSG--DLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1279
Query: 740 DCDPGW----SGTNCDINNNEC-ESNPCVNGGTCKDMTSGYVCTCREGF----SGPNCQT 790
C G+ C I+N+EC + P GG C + Y CTC S C +
Sbjct: 1280 YCSNGYYYHTQRLEC-IDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1338
Query: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLP-------YTGATC---EVVLAPCAPSPCRN 840
N ++ + N G C +V G C P YT C E CA P ++
Sbjct: 1339 NESQSLDD---NLGVCWQEV-GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQD 1394
Query: 841 GGECRQSEDYES 852
S+D+E+
Sbjct: 1395 ------SDDFEA 1400
Score = 228 bits (582), Expect = 4e-59
Identities = 200/625 (32%), Positives = 270/625 (43%), Gaps = 110/625 (17%)
Query: 743 PGWSGTNCDIN---NNECESNPCVNG-GTCKDMTSGYVCTCREGF----SGPNCQTNINE 794
P W+G + + C+ NP V G G C SGY C C GF G C +++E
Sbjct: 532 PAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDE 590
Query: 795 C--ASNPCLNQGTCIDDVAGYKCNC-----LLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
C PC G C + ++C C P +V P PC + G C +
Sbjct: 591 CRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPC-DLGRCENT 648
Query: 848 EDYESFSCVCPTGWQ----GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSG 901
SF CVCP G+Q G +C+ D++EC SP C GA C+N G +RC C AG+ G
Sbjct: 649 PG--SFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRG 704
Query: 902 RNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASD--P 953
CE D+D+C P PC G C + + C C GFR G C +D++ECA P
Sbjct: 705 SACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPP 762
Query: 954 CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTC-L 1008
C G C + S+ C CP GF +G CE + +C G CV+ SF C
Sbjct: 763 CTYG-RCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRT 820
Query: 1009 CPPG--FTGSYCQHDVNECDS--QPCLHGGTCQDGCGSYRCTCPQGYTGPN-----CQNL 1059
CP G C DV+EC S PC G C + GS+RC+C GY P+ C ++
Sbjct: 821 CPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 879
Query: 1060 VHWCDSSPCKNGGKCWQTHTQYRCECPSGW----TGLYC-DVPSVSCEVAAQRQGVDVAR 1114
+ C G+C T + C C G+ G C DV S E
Sbjct: 880 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE-----------D 928
Query: 1115 LCQHGGLCVDAGNTHHCRCQAGYTG----SYCEDLVDEC---SPSPCQNGATCTDYLGGY 1167
LCQ G+C + + C C G+ + C D VDEC P+ C C + G Y
Sbjct: 929 LCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD-VDECRERGPALC-GSQRCENSPGSY 985
Query: 1168 SC--KCVAGYHG--VNCSEEIDECLSHPCQNGGT--CLDLPNTYKC--SCPRG---TQGV 1216
C C GYH +++DEC + + G C + P +Y+C +C G T G
Sbjct: 986 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 1045
Query: 1217 HCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG----DVNEC- 1271
C+ +VD+C +RS C + C + G + C C G+ G R +G DVNEC
Sbjct: 1046 GCQ-DVDECR------NRS-FCGAHAVCQNLPGSFQCLCDQGYEGAR-DGRHCVDVNECE 1096
Query: 1272 -LSNPCDARGTQNCVQRVNDFHCEC 1295
L C G C F C C
Sbjct: 1097 TLQGVC---GAALCENVEGSFLCVC 1118
Score = 227 bits (578), Expect = 1e-58
Identities = 225/808 (27%), Positives = 318/808 (39%), Gaps = 164/808 (20%)
Query: 645 CASSP--CDSGTCLDKIDGYECACEPGYT----GSMCNINIDEC--AGNPCHNGGTCEDG 696
C +P C G C+ + GY CAC+ G+ G+ C I++DEC PC G CE+
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENS 606
Query: 697 INGFTCRCPEGYHD----PTCLSEVNECNS--NPCVHGACRDSLNGYKCDCDPGWS---- 746
F C C G+ CL +V+EC+ PC G C ++ + C C G+
Sbjct: 607 PGSFRCVCGPGFRAGPRAAECL-DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPH 665
Query: 747 GTNCDINNNECESNPCVNG-GTCKDMTSGYVCTCREGFSGPNCQTNINECASNPC-LNQG 804
G +C + +EC +P + G G CK++ + C C GF G C+ +++ECA P G
Sbjct: 666 GASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG 724
Query: 805 TCIDDVAGYKCNCLLPYT----GATCEVVLAPCA--PSPCRNGGECRQSEDYESFSCVCP 858
C + + C C + GA C+ V CA P PC G C +E SF CVCP
Sbjct: 725 RCDNTAGSFHCACPAGFRSRGPGAPCQDV-DECARSPPPCTYG-RCENTEG--SFQCVCP 780
Query: 859 TGWQ----GQTCEVDINECVLSPCRHGASCQNTHGGYRCH-CQAGYS-GRNCETDIDDCR 912
G+Q G CE D++EC G C N+ G ++C C +G+ R TD+D+C
Sbjct: 781 MGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECS 839
Query: 913 PN--PCHNGGSCTDGINTAFCDCLPGFRGTFCEE----DINECAS-DPCRNGANCTDCVD 965
PC G CT+ + C C PG+R D+NEC D C C +
Sbjct: 840 SGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG 899
Query: 966 SYTCTCPAGFS----GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTG----SY 1017
S+ CTC G+ G C + +C+E G C + SF C+CPPG +
Sbjct: 900 SFACTCAPGYRPGPRGASCLD-VDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLAS 958
Query: 1018 CQHDVNEC------------------------DSQPCLHGGT------------------ 1035
C DV+EC D P H G
Sbjct: 959 CL-DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC 1017
Query: 1036 ----CQDGCGSYRCT--CPQGYT---GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP 1086
C++ GSYRCT C GY G CQ++ + S C C ++C C
Sbjct: 1018 GAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCD 1077
Query: 1087 SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH---GGLCVDAGN-------THHC---RC 1133
G+ G V QGV A LC++ LCV + T C R
Sbjct: 1078 QGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRT 1137
Query: 1134 QAG-YTGSYCEDLVDECSPS-------PCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI- 1184
AG + GS + P+ P + +G +C + + I
Sbjct: 1138 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNIL 1197
Query: 1185 ------DECLSHPCQNGGTCLDL---PNT----YKCSCPRG------TQGVHCEINVDDC 1225
EC + G+ + P T Y+ CP G + + +VD+C
Sbjct: 1198 ARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1257
Query: 1226 NPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV--GERCEG-DVNECLSNPCDARGTQ 1282
D V +S G CV+ GYSC C G+ +R E D +EC G +
Sbjct: 1258 QLFRDQVCKS------GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1311
Query: 1283 NCVQRVNDFHCECR----AGHTGRRCES 1306
CV V +HC C + RRC S
Sbjct: 1312 -CVNTVGSYHCTCEPPLVLDGSQRRCVS 1338
Score = 209 bits (532), Expect = 3e-53
Identities = 187/625 (29%), Positives = 256/625 (40%), Gaps = 138/625 (22%)
Query: 884 CQNTHGGYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGF 937
C + GY C C +G+ G C D+D+CR P PC G C + + C C PGF
Sbjct: 561 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGF 618
Query: 938 R-GTFCEE--DINEC--ASDPCRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCT 988
R G E D++EC PC G C + S+ C CPAG+ G C++ +CT
Sbjct: 619 RAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD-VDECT 676
Query: 989 ESSCFNG-GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSYRCT 1046
+S G G C + SF C+CP GF GS C+ DV+EC +P G G C + GS+ C
Sbjct: 677 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA 736
Query: 1047 CPQGY----TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE 1102
CP G+ G CQ++ S P G+C T ++C CP G+ + CE
Sbjct: 737 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP---NTAGSECE 793
Query: 1103 VAAQRQGVDVARLCQHGGLCVDAGNTHHCR-CQAGY--TGSYCEDLVDECSPS--PCQNG 1157
+ + L G CV++ + CR C +G+ C D VDECS PC
Sbjct: 794 DVDECEN----HLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTD-VDECSSGAPPCGPH 848
Query: 1158 ATCTDYLGGYSCKCVAGYHGVN-----CSEEIDECLSHP-CQNGGTCLDLPNTYKCSCP- 1210
CT+ G + C C GY + C+ +++ECL C G CL+ ++ C+C
Sbjct: 849 GHCTNTEGSFRCSCAPGYRAPSGRPGPCA-DVNECLEGDFCFPHGECLNTDGSFACTCAP 907
Query: 1211 ---RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGD 1267
G +G C ++VD+C S C +G C + G + C CPP G R D
Sbjct: 908 GYRPGPRGASC-LDVDEC-------SEEDLC-QSGICTNTDGSFECICPP---GHRAGPD 955
Query: 1268 VNECLS-NPCDAR-----GTQNCVQRVNDFHC--ECRAG-HTG----------------- 1301
+ CL + C R G+Q C + C +C G H G
Sbjct: 956 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 1015
Query: 1302 ----RRCESVINGCKGKP-------------------CKNGGTC---AVASNTARGFICK 1335
+RCE+ + P C+N C AV N F C
Sbjct: 1016 ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1075
Query: 1336 CPAGFEGA----------TCENDARTCGSLRCLN--GGTCISGPRSP------TCLCL-- 1375
C G+EGA CE CG+ C N G P SP T C+
Sbjct: 1076 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1135
Query: 1376 ----GPFTGPECQFPASSPCLGGNP 1396
G F G + Q PA SP L P
Sbjct: 1136 RTSAGTFPGSQPQAPA-SPVLPARP 1159
Score = 163 bits (412), Expect = 2e-39
Identities = 230/872 (26%), Positives = 330/872 (37%), Gaps = 151/872 (17%)
Query: 779 CREGFSGPN--CQTNINECASNPCLNQGTCIDDVAGYKCNC----LLPYTGATC--EVVL 830
C GF N C+ +++ECA+ G C + GY C C LL + ++C + V+
Sbjct: 344 CPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 402
Query: 831 APCAPSPC----RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQN 886
+ A PC R+GG C +C G+ C L P G+
Sbjct: 403 SE-AKGPCFRVLRDGG-CSLPILRNITKQICCCSRVGKAWG---RGCQLCP-PFGSE--- 453
Query: 887 THGGYRCHCQAGYSGRNCETDID-DCRPNPCHNGGSCTDGINTAFCDCLP--GFRGTFCE 943
G+R C AG +D+ + RP T P GF T
Sbjct: 454 ---GFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRL 510
Query: 944 EDINECASDPCRNGANCTDCVDSYTCT--CPAGFSGIHCENNTPDCTESSCFNGGTCVDG 1001
E E DP + ++T +G S C+ N C G C+
Sbjct: 511 EPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC------GPGRCISR 564
Query: 1002 INSFTCLCPPGFT----GSYCQHDVNECDS--QPCLHGGTCQDGCGSYRCTCPQGY-TGP 1054
+ +TC C GF G+ C DV+EC PC G C++ GS+RC C G+ GP
Sbjct: 565 PSGYTCACDSGFRLSPQGTRCI-DVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGP 622
Query: 1055 N---CQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVD 1111
C ++ P + G+C T + C CP+G+ + Q G
Sbjct: 623 RAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG-- 680
Query: 1112 VARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS--PSPCQNGATCTDYLGGYSC 1169
LC G C + + C C AG+ GS CE+ VDEC+ P PC G C + G + C
Sbjct: 681 ---LCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR-CDNTAGSFHC 735
Query: 1170 KCVAGYH----GVNCSEEIDECL-SHPCQNGGTCLDLPNTYKCSCPRG----TQGVHCEI 1220
C AG+ G C +++DEC S P G C + +++C CP G T G CE
Sbjct: 736 ACPAGFRSRGPGAPC-QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE- 793
Query: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC-TCPPG--FVGERCEGDVNECLSN--P 1275
+VD+C + + CV+ G + C TCP G RC DV+EC S P
Sbjct: 794 DVDECENHLACPGQE--------CVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSGAPP 844
Query: 1276 CDARGTQNCVQRVNDFHCECRAGH---TGRR--CESVINGCKGKPCKNGGTCAVASNTAR 1330
C G +C F C C G+ +GR C V +G C G C NT
Sbjct: 845 CGPHG--HCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECL---NTDG 899
Query: 1331 GFICKCPAGFE----GATCENDARTCGSLRCLNGGTCISGPRSPTCLCL-GPFTGPECQF 1385
F C C G+ GA+C D C G C + S C+C G GP+
Sbjct: 900 SFACTCAPGYRPGPRGASCL-DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDL-- 956
Query: 1386 PASSPCLGGNPCYNQGT-------CEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGR 1438
+ CL + C +G CE + S YRC + D G AG
Sbjct: 957 ---ASCLDVDECRERGPALCGSQRCENSPGS--YRC------------VRDCDPGYHAGP 999
Query: 1439 DIPPPLIEEA-------CELPECQEDAGNKVCSLQCNNHACGWDGGDCS----------L 1481
+ ++E C C+ G+ C+ C+ GG C
Sbjct: 1000 EGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFC 1059
Query: 1482 NFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFS 1541
+ +N S QC D + + C+ D +C+ +G C C++
Sbjct: 1060 GAHAVCQNLPGSFQC---LCDQGYEGARDGRHCV-DVNECETLQGVCGA---ALCENVEG 1112
Query: 1542 DGHCDQGCNSAECEWDGLDCAEHVPERLAAGT 1573
C C ++ E+D + VP R +AGT
Sbjct: 1113 SFLC--VCPNSPEEFDPM-TGRCVPPRTSAGT 1141
Score = 125 bits (313), Expect = 7e-28
Identities = 142/531 (26%), Positives = 187/531 (35%), Gaps = 117/531 (22%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPR-----CQDPNPCLSTP-CKNAGTCHVV 77
CS C G C G+ C C + P C D N CL C G C
Sbjct: 838 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNT 897
Query: 78 DRRGVADYACSCALGF-SGPLCLTPLD-NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSG 135
D +AC+CA G+ GP + LD + C G C T ++C CPPG
Sbjct: 898 D----GSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC-TNTDGSFECICPPGHRA 952
Query: 136 ----KSCQQADPCAS-NPCANGGQ-CLPFEASYIC--HCPPSFH-GP--TCRQDVNECGQ 184
SC D C P G Q C SY C C P +H GP TC DV+EC +
Sbjct: 953 GPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC-DDVDECQE 1011
Query: 185 -KPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHEC 243
P +C C N GSYRC P C+ Y P CQ+ CR
Sbjct: 1012 YGPEIC-GAQRCENTPGSYRCT-------PACDPGYQPTPGGGCQDVDECRNRSFCGAHA 1063
Query: 244 AC--LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQL 301
C LPG C++ + ++G CV DV+EC+
Sbjct: 1064 VCQNLPGSFQCLCDQGYE-----GARDGRHCV---------------------DVNECET 1097
Query: 302 MPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC----ASAACFHGATCH------ 351
+ C C N G + CVC N + E+ C SA F G+
Sbjct: 1098 LQGVC-GAALCENVEGSFLCVCPN--SPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPV 1154
Query: 352 ----------DRVASFYCECPHGRTGLLCHLNDA------------------CISNPCNE 383
R S + P G C+ + A C +
Sbjct: 1155 LPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW 1214
Query: 384 GSNC------DTNPVNGKAICTCPSGYTGP----ACSQDVDECSLGANPCEHAGKCINTL 433
GS C T +++C GY P + +DVDEC L + +G C+NT
Sbjct: 1215 GSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTA 1274
Query: 434 GSFECQCLQG--YTGPRCE-IDVNECV-SNPCQNDATCLDQIGEFQCICMP 480
+ C C G Y R E ID +EC P C++ +G + C C P
Sbjct: 1275 PGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Score = 52.8 bits (125), Expect = 4e-06
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 11/83 (13%)
Query: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNEC----VSNPCQN 463
+ +EC + + C + G+C+ F C+C GY T C +D+NEC ++P
Sbjct: 1533 EAEECGI-LDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1589
Query: 464 DATCLDQIGEFQCICMPGYEGVH 486
+A CL+ G F+CIC PG+ H
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTH 1612
Score = 49.7 bits (117), Expect = 4e-05
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 526 QYDVDECASTP-CKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPDP-----C 575
+ + +EC C NG +C+ P +TC C +GY T C VDI+ECD C
Sbjct: 1531 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLC 1588
Query: 576 HYGSCKDGVATFTCLCRPGYT----GHHC 600
C + +F C+CRPG+ HHC
Sbjct: 1589 VNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 7/82 (8%)
Query: 488 EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQY---DVDEC----ASTPCKNG 540
E+ +EC NGRC+ F C C G+ + + D++EC A++P
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 541 AKCLDGPNTYTCVCTEGYTGTH 562
A+CL+ ++ C+C G+ TH
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTH 1612
Score = 47.0 bits (110), Expect = 2e-04
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 12/92 (13%)
Query: 670 YTGSMCN----INIDECAGNPCHNGGTCEDGINGFTCRCPEGYH-DPTCLS--EVNECN- 721
Y GS+ + +EC G C GFTCRC +GY D T ++ ++NEC+
Sbjct: 1521 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDE 1580
Query: 722 ----SNPCVHGACRDSLNGYKCDCDPGWSGTN 749
S CV+ C ++ ++C C PG++ T+
Sbjct: 1581 AEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1612
Score = 40.4 bits (93), Expect = 0.023
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 10/70 (14%)
Query: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCE---VDINEC----VLSPCRHGASCQNTHGG 890
C NG R E F+C C G++ VDINEC SP A C NT G
Sbjct: 1543 CTNGRCVRVPE---GFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1599
Query: 891 YRCHCQAGYS 900
+RC C+ G++
Sbjct: 1600 FRCICRPGFA 1609
Score = 39.7 bits (91), Expect = 0.038
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 1183 EIDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1241
E +EC + C NG C+ +P + C C G + + D N + + SP C N
Sbjct: 1533 EAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN- 1590
Query: 1242 GTCVDQVGGYSCTCPPGF 1259
C++ G + C C PGF
Sbjct: 1591 ARCLNTDGSFRCICRPGF 1608
Score = 38.5 bits (88), Expect = 0.086
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 10/68 (14%)
Query: 992 CFNGGTCVDGINSFTCLCPPGF----TGSYCQHDVNECD----SQPCLHGGTCQDGCGSY 1043
C NG CV FTC C G+ T C D+NECD + P C + GS+
Sbjct: 1543 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACV-DINECDEAEAASPLCVNARCLNTDGSF 1600
Query: 1044 RCTCPQGY 1051
RC C G+
Sbjct: 1601 RCICRPGF 1608
Score = 38.1 bits (87), Expect = 0.11
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 11/86 (12%)
Query: 140 QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQ---DVNECGQKPG---LCRHGG 193
+A+ C G+C+ + C C + R D+NEC + LC +
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA- 1591
Query: 194 TCHNEVGSYRCVCR----ATHTGPNC 215
C N GS+RC+CR TH +C
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 37.4 bits (85), Expect = 0.19
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 21/92 (22%)
Query: 943 EEDINECAS-DPCRNGANCTDCVDSYTCTCPAGF----SGIHC---------ENNTPDCT 988
E + EC D C NG C + +TC C G+ + + C E +P C
Sbjct: 1531 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 989 ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH 1020
+ C N DG SF C+C PGF ++ H
Sbjct: 1590 NARCLN----TDG--SFRCICRPGFAPTHQPH 1615
Score = 36.6 bits (83), Expect = 0.33
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 11/87 (12%)
Query: 636 PNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYTGSMCN---INIDEC----AGNPC 687
P E+ ++C C +G C+ +G+ C C GY M ++I+EC A +P
Sbjct: 1528 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1587
Query: 688 HNGGTCEDGINGFTCRCPEGY---HDP 711
C + F C C G+ H P
Sbjct: 1588 CVNARCLNTDGSFRCICRPGFAPTHQP 1614
Score = 33.9 bits (76), Expect = 2.1
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 12/79 (15%)
Query: 716 EVNECNS-NPCVHGACRDSLNGYKCDCDPGW----SGTNCDINNNECE-----SNPCVNG 765
E EC + C +G C G+ C C G+ + C ++ NEC+ S CVN
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNA 1591
Query: 766 GTCKDMTSGYVCTCREGFS 784
C + + C CR GF+
Sbjct: 1592 -RCLNTDGSFRCICRPGFA 1609
Score = 33.1 bits (74), Expect = 3.6
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 867 EVDINEC-VLSPCRHGASCQNTHGGYRCHCQAGY---SGRNCETDIDDC----RPNPCHN 918
E++ EC +L C +G C G+ C C GY R DI++C +P
Sbjct: 1531 ELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 919 GGSCTDGINTAFCDCLPGFRGT 940
C + + C C PGF T
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPT 1611
Score = 33.1 bits (74), Expect = 3.6
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 8/70 (11%)
Query: 264 NNCKNGGACVDGVNTYNCRCPP----EWTGQYCTE--DVDECQLMPNACQNGGTCHNTHG 317
+ C NG CV + CRC + T C + + DE + C N C NT G
Sbjct: 1541 DGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA-RCLNTDG 1598
Query: 318 GYNCVCVNGW 327
+ C+C G+
Sbjct: 1599 SFRCICRPGF 1608
Score = 32.3 bits (72), Expect = 6.1
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 14/107 (13%)
Query: 1242 GTCVDQVGGYSCTCP-PGFVGER--CEG-----DVNECLSNPCDARGTQNCVQRVNDFHC 1293
G C ++ G C P PG + C G V++C C R + D C
Sbjct: 287 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDC--QLCSERLGNSERVSAPDGPC 344
Query: 1294 ECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1340
CE V G C++G CA NT G+ C CP GF
Sbjct: 345 PTGFERVNGSCEDVDECATGGRCQHG-ECA---NTRGGYTCVCPDGF 387
Score = 32.0 bits (71), Expect = 8.0
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 15/94 (15%)
Query: 1137 YTGSYCEDL----VDECSP-SPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDEC 1187
Y GS E +EC C NG C G++C+C GY + C +I+EC
Sbjct: 1521 YAGSLAEPYEELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMAC-VDINEC 1578
Query: 1188 ----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
+ P CL+ +++C C G H
Sbjct: 1579 DEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1612
Score = 32.0 bits (71), Expect = 8.0
Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ---TNINEC----ASNPCLNQ 803
++ EC G C + G+ C C +G+ + +INEC A++P
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 804 GTCIDDVAGYKCNC 817
C++ ++C C
Sbjct: 1591 ARCLNTDGSFRCIC 1604
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 261 bits (666), Expect = 8e-69
Identities = 144/382 (37%), Positives = 184/382 (48%), Gaps = 38/382 (9%)
Query: 662 YECACEPGYTGS----MCNINIDECAGNPCHNGG--TCEDGINGFTCRCPEGYHDPTCLS 715
Y C Y G +C D C G +C G G C+ P CLS
Sbjct: 171 YRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQ------QPICLS 224
Query: 716 EVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGY 775
+E N G C +C C PGW G C NEC + GTC ++ +
Sbjct: 225 GCHEQN------GYCSKPA---ECLCRPGWQGRLC----NECIPHNGCRHGTC---STPW 268
Query: 776 VCTCREGFSGPNCQTNINECASN-PCLNQGTCIDD-VAGYKCNCLLPYTGATCEVVLAPC 833
CTC EG+ G C ++N C + PC N TC + Y C C YTG CE+ L+ C
Sbjct: 269 QCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSEC 328
Query: 834 APSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGG--Y 891
+PCRNGG C+ ED + C+CP G+ G CE C SPC +G SC+ + G Y
Sbjct: 329 DSNPCRNGGSCKDQED--GYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANY 386
Query: 892 RCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS 951
C C ++G NCE +D C NPC NGG C + + C C PGF GT+CE +++CA
Sbjct: 387 ACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCAR 446
Query: 952 DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNT--PDCTESSCFNGGTCVDGI--NSFTC 1007
+PC +G C D + CTCPAGFSG CE T C S CFN TC + ++F C
Sbjct: 447 NPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVC 506
Query: 1008 LCPPGFTGSYCQHDVNECDSQP 1029
CP GF GS C+ V S P
Sbjct: 507 NCPYGFVGSRCEFPVGLPPSFP 528
Score = 257 bits (656), Expect = 1e-67
Identities = 138/365 (37%), Positives = 174/365 (47%), Gaps = 23/365 (6%)
Query: 624 AYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECA 683
+Y C G NC C G + + DG +C PG+TG C I C
Sbjct: 170 SYRVICSDNYYGDNCSRL---CKKRNDHFGHYVCQPDG-NLSCLPGWTGEYCQQPI--CL 223
Query: 684 GNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC-NSNPCVHGACRDSLNGYKCDCD 742
G C C C G+ C NEC N C HG C ++C CD
Sbjct: 224 SGCHEQNGYCSKPAE---CLCRPGWQGRLC----NECIPHNGCRHGTCSTP---WQCTCD 273
Query: 743 PGWSGTNCDINNNEC-ESNPCVNGGTCKDMTS-GYVCTCREGFSGPNCQTNINECASNPC 800
GW G CD + N C +PC NG TC + Y CTCR G++G +C+ ++EC SNPC
Sbjct: 274 EGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPC 333
Query: 801 LNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTG 860
N G+C D GY C C Y G CE CA SPC NGG CR+ +++C CP
Sbjct: 334 RNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPN 393
Query: 861 WQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 920
+ G CE ++ C +PC +G C N C C+ G++G CE + DC NPC +GG
Sbjct: 394 FTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGG 453
Query: 921 SCTDGINTAFCDCLPGFRGTFCE--EDINECASDPCRNGANC-TD-CVDSYTCTCPAGFS 976
+C D N C C GF G CE I+ CAS PC N A C TD D++ C CP GF
Sbjct: 454 TCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFV 513
Query: 977 GIHCE 981
G CE
Sbjct: 514 GSRCE 518
Score = 248 bits (634), Expect = 4e-65
Identities = 134/375 (35%), Positives = 179/375 (47%), Gaps = 39/375 (10%)
Query: 737 YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC------TCREGFSGPNCQT 790
Y+ C + G NC + C+ D YVC +C G++G CQ
Sbjct: 171 YRVICSDNYYGDNC---SRLCKKR--------NDHFGHYVCQPDGNLSCLPGWTGEYCQQ 219
Query: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDY 850
I C S G C +C C + G C C P NG CR
Sbjct: 220 PI--CLSGCHEQNGYCSKPA---ECLCRPGWQGRLCN----ECIP---HNG--CRHGTCS 265
Query: 851 ESFSCVCPTGWQGQTCEVDINECVL-SPCRHGASCQNT-HGGYRCHCQAGYSGRNCETDI 908
+ C C GW G C+ D+N C SPC++GA+C N+ Y C C+ GY+G +CE ++
Sbjct: 266 TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELEL 325
Query: 909 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVD--S 966
+C NPC NGGSC D + C C PG+ G CE CA PC NG +C + +
Sbjct: 326 SECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 385
Query: 967 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECD 1026
Y C CP F+G +CE CT + C NGG C++ S C C PGFTG+YC+ V++C
Sbjct: 386 YACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCA 445
Query: 1027 SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ--NLVHWCDSSPCKNGGKCWQ--THTQYR 1082
PC HGGTC D CTCP G++G C+ + C SSPC N C+ + +
Sbjct: 446 RNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFV 505
Query: 1083 CECPSGWTGLYCDVP 1097
C CP G+ G C+ P
Sbjct: 506 CNCPYGFVGSRCEFP 520
Score = 248 bits (632), Expect = 7e-65
Identities = 140/387 (36%), Positives = 191/387 (49%), Gaps = 51/387 (13%)
Query: 852 SFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTH-GGYRCH------CQAGYSGRNC 904
S+ +C + G C C+ +N H G Y C C G++G C
Sbjct: 170 SYRVICSDNYYGDNCS--------RLCKK----RNDHFGHYVCQPDGNLSCLPGWTGEYC 217
Query: 905 ETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS-DPCRNGANCTDC 963
+ I C G C+ A C C PG++G C NEC + CR+G C
Sbjct: 218 QQPI--CLSGCHEQNGYCS---KPAECLCRPGWQGRLC----NECIPHNGCRHGT----C 264
Query: 964 VDSYTCTCPAGFSGIHCENNTPDCTESS-CFNGGTCVD-GINSFTCLCPPGFTGSYCQHD 1021
+ CTC G+ G+ C+ + CT S C NG TC + G S+TC C PG+TG C+ +
Sbjct: 265 STPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELE 324
Query: 1022 VNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH--T 1079
++ECDS PC +GG+C+D Y C CP GY G +C++ C SPC NGG C + +
Sbjct: 325 LSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGA 384
Query: 1080 QYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTG 1139
Y CECP +TG C+ C + C +GG C++ G + CRC+ G+TG
Sbjct: 385 NYACECPPNFTGSNCEKKVDRC----------TSNPCANGGQCLNRGPSRMCRCRPGFTG 434
Query: 1140 SYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS--EEIDECLSHPCQNGGT 1197
+YCE V +C+ +PC +G TC D G C C AG+ G C ID C S PC N T
Sbjct: 435 TYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRAT 494
Query: 1198 CL-DLP-NTYKCSCPRGTQGVHCEINV 1222
C DL +T+ C+CP G G CE V
Sbjct: 495 CYTDLSTDTFVCNCPYGFVGSRCEFPV 521
Score = 241 bits (614), Expect = 9e-63
Identities = 132/376 (35%), Positives = 179/376 (47%), Gaps = 48/376 (12%)
Query: 435 SFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQC------ICMPGYEGVHCE 488
S+ C Y G C S C+ D G + C C+PG+ G +C+
Sbjct: 170 SYRVICSDNYYGDNC--------SRLCKKRN---DHFGHYVCQPDGNLSCLPGWTGEYCQ 218
Query: 489 VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN 548
C S NG C +C C G+ G LC +EC NG +
Sbjct: 219 QPI--CLSGCHEQNGYCSKPA---ECLCRPGWQGRLC----NECIP---HNGCRHGTCST 266
Query: 549 TYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVA-------TFTCLCRPGYTGHHCE 601
+ C C EG+ G C+ D++ C H+ CK+G ++TC CRPGYTG CE
Sbjct: 267 PWQCTCDEGWGGLFCDQDLNYCT----HHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCE 322
Query: 602 TNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKID 660
++EC S PCR+GG+C+D+++ Y C C G G +CE + CA SPC + G+C ++
Sbjct: 323 LELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQ 382
Query: 661 G--YECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVN 718
G Y C C P +TGS C +D C NPC NGG C + CRC G+ C V+
Sbjct: 383 GANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVS 442
Query: 719 ECNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINN--NECESNPCVNGGTCKD--MTS 773
+C NPC H G C D NG C C G+SG C++ + C S+PC N TC T
Sbjct: 443 DCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTD 502
Query: 774 GYVCTCREGFSGPNCQ 789
+VC C GF G C+
Sbjct: 503 TFVCNCPYGFVGSRCE 518
Score = 239 bits (611), Expect = 2e-62
Identities = 134/382 (35%), Positives = 181/382 (47%), Gaps = 41/382 (10%)
Query: 891 YRCHCQAGYSGRNCETDIDDCRPNPCHNGGS-CTDGINTAFCDCLPGFRGTFCEEDINEC 949
YR C Y G NC C+ H G C N + CLPG+ G +C++ I C
Sbjct: 171 YRVICSDNYYGDNCSRL---CKKRNDHFGHYVCQPDGNLS---CLPGWTGEYCQQPI--C 222
Query: 950 ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLC 1009
S C+ + C C G+ G C +C + GTC + C C
Sbjct: 223 LSGCHEQNGYCSKPAE---CLCRPGWQGRLCN----ECIPHNGCRHGTCS---TPWQCTC 272
Query: 1010 PPGFTGSYCQHDVNECDSQ-PCLHGGTCQD-GCGSYRCTCPQGYTGPNCQNLVHWCDSSP 1067
G+ G +C D+N C PC +G TC + G SY CTC GYTG +C+ + CDS+P
Sbjct: 273 DEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNP 332
Query: 1068 CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA-- 1125
C+NGG C Y C CP G+ GL+C+ ++SC + C +GG C +
Sbjct: 333 CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSP----------CFNGGSCRERNQ 382
Query: 1126 GNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEID 1185
G + C C +TGS CE VD C+ +PC NG C + C+C G+ G C +
Sbjct: 383 GANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVS 442
Query: 1186 ECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV 1245
+C +PC +GGTC DL N C+CP G G CE+ +D + SP CFN TC
Sbjct: 443 DCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS-----IDACASSP-CFNRATCY 496
Query: 1246 DQVG--GYSCTCPPGFVGERCE 1265
+ + C CP GFVG RCE
Sbjct: 497 TDLSTDTFVCNCPYGFVGSRCE 518
Score = 238 bits (606), Expect = 7e-62
Identities = 130/379 (34%), Positives = 194/379 (51%), Gaps = 46/379 (12%)
Query: 319 YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE------CPHGRTGLLCHL 372
Y +C + + G++CS C +D + C+ C G TG C
Sbjct: 171 YRVICSDNYYGDNCSRL---CKKR--------NDHFGHYVCQPDGNLSCLPGWTGEYCQ- 218
Query: 373 NDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINT 432
C+S C+E + + P A C C G+ G C++ + N C H G C
Sbjct: 219 QPICLSG-CHEQNGYCSKP----AECLCRPGWQGRLCNECIPH-----NGCRH-GTCSTP 267
Query: 433 LGSFECQCLQGYTGPRCEIDVNECVSN-PCQNDATCLDQIGE--FQCICMPGYEGVHCEV 489
++C C +G+ G C+ D+N C + PC+N ATC + G+ + C C PGY GV CE+
Sbjct: 268 ---WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNS-GQRSYTCTCRPGYTGVDCEL 323
Query: 490 NTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLD---G 546
EC S+PC + G C D+ + + C CP G+ G C++ CA +PC NG C + G
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQG 383
Query: 547 PNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNIN 605
N Y C C +TG++CE +D C +PC + G C + + C CRPG+TG +CE +++
Sbjct: 384 AN-YACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVS 442
Query: 606 ECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI--NLDDCASSPC-DSGTCLDKI--D 660
+C+ PC HGGTC D +N +C C G +G CE+ ++D CASSPC + TC + D
Sbjct: 443 DCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTD 502
Query: 661 GYECACEPGYTGSMCNINI 679
+ C C G+ GS C +
Sbjct: 503 TFVCNCPYGFVGSRCEFPV 521
Score = 236 bits (603), Expect = 2e-61
Identities = 131/388 (33%), Positives = 184/388 (47%), Gaps = 41/388 (10%)
Query: 161 SYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCV------CRATHTGPN 214
SY C +++G C + LC+ ++ G Y C C TG
Sbjct: 170 SYRVICSDNYYGDNCSR----------LCKKR---NDHFGHYVCQPDGNLSCLPGWTGEY 216
Query: 215 CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVD 274
C++P + S QNG +P EC C PG+ G+ C E I P N C++G
Sbjct: 217 CQQP-ICLSGCHEQNGYCSKPA-----ECLCRPGWQGRLCNECI---PHNGCRHGTCSTP 267
Query: 275 GVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT-HGGYNCVCVNGWTGEDCS 333
+ C C W G +C +D++ C + C+NG TC N+ Y C C G+TG DC
Sbjct: 268 ----WQCTCDEGWGGLFCDQDLNYCT-HHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCE 322
Query: 334 ENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLC-HLNDACISNPCNEGSNCDTNPV 392
+ +C S C +G +C D+ ++C CP G GL C H +C +PC G +C
Sbjct: 323 LELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQ 382
Query: 393 NGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEID 452
C CP +TG C + VD C+ +NPC + G+C+N S C+C G+TG CE+
Sbjct: 383 GANYACECPPNFTGSNCEKKVDRCT--SNPCANGGQCLNRGPSRMCRCRPGFTGTYCELH 440
Query: 453 VNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNT--DECASSPCLHNGRCLDKIN 510
V++C NPC + TC D C C G+ G CEV T D CASSPC + C ++
Sbjct: 441 VSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLS 500
Query: 511 E--FQCECPTGFTGHLCQYDVDECASTP 536
F C CP GF G C++ V S P
Sbjct: 501 TDTFVCNCPYGFVGSRCEFPVGLPPSFP 528
Score = 234 bits (596), Expect = 1e-60
Identities = 130/377 (34%), Positives = 181/377 (48%), Gaps = 35/377 (9%)
Query: 201 SYRCVCRATHTGPNCERPYVPCSPSPCQNGG-TCRPTGDVTHECACLPGFTGQNCEENID 259
SYR +C + G NC R C G C+P G+++ CLPG+TG+ C++ I
Sbjct: 170 SYRVICSDNYYGDNCSRL---CKKRNDHFGHYVCQPDGNLS----CLPGWTGEYCQQPI- 221
Query: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGY 319
C + G C C C P W G+ C E + N C++G TC +
Sbjct: 222 -CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCNECIPH-----NGCRHG-TCSTP---W 268
Query: 320 NCVCVNGWTGEDCSENIDDCAS-AACFHGATCHDR-VASFYCECPHGRTGLLCHLN-DAC 376
C C GW G C ++++ C + C +GATC + S+ C C G TG+ C L C
Sbjct: 269 QCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSEC 328
Query: 377 ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCI--NTLG 434
SNPC G +C C CP GY G C C+ +PC + G C N
Sbjct: 329 DSNPCRNGGSCKDQEDGYH--CLCPPGYYGLHCEHSTLSCA--DSPCFNGGSCRERNQGA 384
Query: 435 SFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDEC 494
++ C+C +TG CE V+ C SNPC N CL++ C C PG+ G +CE++ +C
Sbjct: 385 NYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDC 444
Query: 495 ASSPCLHNGRCLDKINEFQCECPTGFTGHLCQY--DVDECASTPCKNGAKCLD--GPNTY 550
A +PC H G C D N C CP GF+G C+ +D CAS+PC N A C +T+
Sbjct: 445 ARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTF 504
Query: 551 TCVCTEGYTGTHCEVDI 567
C C G+ G+ CE +
Sbjct: 505 VCNCPYGFVGSRCEFPV 521
Score = 232 bits (591), Expect = 4e-60
Identities = 140/381 (36%), Positives = 179/381 (46%), Gaps = 58/381 (15%)
Query: 1042 SYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCE------CPSGWTGLYCD 1095
SYR C Y G NC L CK + Y C+ C GWTG YC
Sbjct: 170 SYRVICSDNYYGDNCSRL--------CKKRNDHFG---HYVCQPDGNLSCLPGWTGEYCQ 218
Query: 1096 VPSVSCEVAAQRQGVDVAR----LCQHG------GLCVDAGNTHH--------CRCQAGY 1137
P C Q ++ LC+ G C+ H C C G+
Sbjct: 219 QPI--CLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGW 276
Query: 1138 TGSYCEDLVDECSP-SPCQNGATCTDY-LGGYSCKCVAGYHGVNCSEEIDECLSHPCQNG 1195
G +C+ ++ C+ SPC+NGATC++ Y+C C GY GV+C E+ EC S+PC+NG
Sbjct: 277 GGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNG 336
Query: 1196 GTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGG--YSC 1253
G+C D + Y C CP G G+HCE + C + SP CFN G+C ++ G Y+C
Sbjct: 337 GSCKDQEDGYHCLCPPGYYGLHCEHSTLSC-------ADSP-CFNGGSCRERNQGANYAC 388
Query: 1254 TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKG 1313
CPP F G CE V+ C SNPC A G Q C+ R C CR G TG CE ++ C
Sbjct: 389 ECPPNFTGSNCEKKVDRCTSNPC-ANGGQ-CLNRGPSRMCRCRPGFTGTYCELHVSDCAR 446
Query: 1314 KPCKNGGTCAVASNTARGFICKCPAGFEGATCE--NDARTCGSLRCLNGGTCISGPRSPT 1371
PC +GGTC N G +C CPAGF G CE C S C N TC + + T
Sbjct: 447 NPCAHGGTCHDLEN---GLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDT 503
Query: 1372 CLCLGP--FTGPECQFPASSP 1390
+C P F G C+FP P
Sbjct: 504 FVCNCPYGFVGSRCEFPVGLP 524
Score = 225 bits (574), Expect = 4e-58
Identities = 132/388 (34%), Positives = 178/388 (45%), Gaps = 46/388 (11%)
Query: 966 SYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNEC 1025
SY C + G +C C + + G + +CL PG+TG YCQ +
Sbjct: 170 SYRVICSDNYYGDNCSRL---CKKRNDHFGHYVCQPDGNLSCL--PGWTGEYCQQPI--- 221
Query: 1026 DSQPCLHGGTCQDGCGSY--RCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRC 1083
CL G Q+G S C C G+ G C + + C++G T ++C
Sbjct: 222 ----CLSGCHEQNGYCSKPAECLCRPGWQGRLCNECI---PHNGCRHG----TCSTPWQC 270
Query: 1084 ECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGN-THHCRCQAGYTGSYC 1142
C GW GL+CD C + C++G C ++G ++ C C+ GYTG C
Sbjct: 271 TCDEGWGGLFCDQDLNYCTHHSP---------CKNGATCSNSGQRSYTCTCRPGYTGVDC 321
Query: 1143 EDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLP 1202
E + EC +PC+NG +C D GY C C GY+G++C C PC NGG+C +
Sbjct: 322 ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERN 381
Query: 1203 N--TYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260
Y C CP G +CE VD C S C N G C+++ C C PGF
Sbjct: 382 QGANYACECPPNFTGSNCEKKVDRCT--------SNPCANGGQCLNRGPSRMCRCRPGFT 433
Query: 1261 GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE--SVINGCKGKPCKN 1318
G CE V++C NPC GT C N C C AG +GRRCE + I+ C PC N
Sbjct: 434 GTYCELHVSDCARNPCAHGGT--CHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFN 491
Query: 1319 GGTCAVASNTARGFICKCPAGFEGATCE 1346
TC +T F+C CP GF G+ CE
Sbjct: 492 RATCYTDLSTDT-FVCNCPYGFVGSRCE 518
Score = 225 bits (573), Expect = 5e-58
Identities = 122/349 (34%), Positives = 169/349 (48%), Gaps = 36/349 (10%)
Query: 963 CVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDV 1022
C +C G++G +C+ P C G C CLC PG+ G C
Sbjct: 200 CQPDGNLSCLPGWTGEYCQQ--PICLSGCHEQNGYCSKPAE---CLCRPGWQGRLC---- 250
Query: 1023 NECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDS-SPCKNGGKCWQT-HTQ 1080
NEC GTC ++CTC +G+ G C +++C SPCKNG C +
Sbjct: 251 NECIPHNGCRHGTCST---PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRS 307
Query: 1081 YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS 1140
Y C C G+TG+ C++ C+ + C++GG C D + +HC C GY G
Sbjct: 308 YTCTCRPGYTGVDCELELSECD----------SNPCRNGGSCKDQEDGYHCLCPPGYYGL 357
Query: 1141 YCEDLVDECSPSPCQNGATCTDYLGG--YSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC 1198
+CE C+ SPC NG +C + G Y+C+C + G NC +++D C S+PC NGG C
Sbjct: 358 HCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQC 417
Query: 1199 LDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPG 1258
L+ + C C G G +CE++V DC +R+P C + GTC D G CTCP G
Sbjct: 418 LNRGPSRMCRCRPGFTGTYCELHVSDC-------ARNP-CAHGGTCHDLENGLMCTCPAG 469
Query: 1259 FVGERCE--GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE 1305
F G RCE ++ C S+PC R T + F C C G G RCE
Sbjct: 470 FSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 219 bits (557), Expect = 4e-56
Identities = 122/334 (36%), Positives = 166/334 (49%), Gaps = 29/334 (8%)
Query: 129 CPPGWSGKSCQQADPCASNPCANGGQC-LPFEASYICHCPPSFHGPTCRQDVNECGQKPG 187
C PGW+G+ CQQ C S G C P E C C P + G C NEC G
Sbjct: 208 CLPGWTGEYCQQ-PICLSGCHEQNGYCSKPAE----CLCRPGWQGRLC----NECIPHNG 258
Query: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS-PSPCQNGGTCRPTGDVTHECACL 246
CRH GTC ++C C G C++ C+ SPC+NG TC +G ++ C C
Sbjct: 259 -CRH-GTCST---PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCR 313
Query: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
PG+TG +CE + +C N C+NGG+C D + Y+C CPP + G +C C P C
Sbjct: 314 PGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSP--C 371
Query: 307 QNGGTCHNTHGG--YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHG 364
NGG+C + G Y C C +TG +C + +D C S C +G C +R S C C G
Sbjct: 372 FNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPG 431
Query: 365 RTGLLCHLN-DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACS--QDVDECSLGAN 421
TG C L+ C NPC G C + + +CTCP+G++G C +D C+ ++
Sbjct: 432 FTGTYCELHVSDCARNPCAHGGTC--HDLENGLMCTCPAGFSGRRCEVRTSIDACA--SS 487
Query: 422 PCEHAGKCINTLG--SFECQCLQGYTGPRCEIDV 453
PC + C L +F C C G+ G RCE V
Sbjct: 488 PCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPV 521
Score = 200 bits (509), Expect = 1e-50
Identities = 113/323 (34%), Positives = 148/323 (45%), Gaps = 30/323 (9%)
Query: 21 GPRCSQPGETCLNGGKCEAANG----TEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHV 76
G C QP CL+G C NG C+C + G C N C+ GTC
Sbjct: 214 GEYCQQP--ICLSG--CHEQNGYCSKPAECLCRPGWQGRLC---NECIPHNGCRHGTCST 266
Query: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
+ C+C G+ G C L+ +PC+NG TC Y C C PG++G
Sbjct: 267 -------PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGV 319
Query: 137 SCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC 195
C+ + C SNPC NGG C E Y C CPP ++G C C P C +GG+C
Sbjct: 320 DCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSP--CFNGGSC 377
Query: 196 --HNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQN 253
N+ +Y C C TG NCE+ C+ +PC NGG C G + C C PGFTG
Sbjct: 378 RERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGP-SRMCRCRPGFTGTY 436
Query: 254 CEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC--TEDVDECQLMPNACQNGGT 311
CE ++ DC N C +GG C D N C CP ++G+ C +D C P C N T
Sbjct: 437 CELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP--CFNRAT 494
Query: 312 CHN--THGGYNCVCVNGWTGEDC 332
C+ + + C C G+ G C
Sbjct: 495 CYTDLSTDTFVCNCPYGFVGSRC 517
Score = 174 bits (442), Expect = 8e-43
Identities = 110/330 (33%), Positives = 151/330 (45%), Gaps = 44/330 (13%)
Query: 1109 GVDVARLCQ----HGG--LCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTD 1162
G + +RLC+ H G +C GN C G+TG YC+ + C +G C +
Sbjct: 181 GDNCSRLCKKRNDHFGHYVCQPDGNLS---CLPGWTGEYCQQPI-------CLSG--CHE 228
Query: 1163 YLGGYS----CKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHC 1218
G S C C G+ G C+E C+ H GTC ++C+C G G+ C
Sbjct: 229 QNGYCSKPAECLCRPGWQGRLCNE----CIPHNGCRHGTC---STPWQCTCDEGWGGLFC 281
Query: 1219 EINVDDCNPPVDPVSRSPKCFNNGTCVDQ-VGGYSCTCPPGFVGERCEGDVNECLSNPCD 1277
+ +++ C SP C N TC + Y+CTC PG+ G CE +++EC SNPC
Sbjct: 282 DQDLNYCT------HHSP-CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPC- 333
Query: 1278 ARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCP 1337
R +C + + +HC C G+ G CE C PC NGG+C N + C+CP
Sbjct: 334 -RNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCR-ERNQGANYACECP 391
Query: 1338 AGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPC 1397
F G+ CE C S C NGG C++ S C C FTG C+ S NPC
Sbjct: 392 PNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSD--CARNPC 449
Query: 1398 YNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427
+ GTC C CPA F+G C +
Sbjct: 450 AHGGTCHDLENG--LMCTCPAGFSGRRCEV 477
Score = 157 bits (396), Expect = 2e-37
Identities = 86/232 (37%), Positives = 112/232 (48%), Gaps = 14/232 (6%)
Query: 31 CLNGGKCE-AANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACS 88
C NG C + + C C + G C+ + + C S PC+N G+C + Y C
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQED----GYHCL 349
Query: 89 CALGFSGPLCLTPLDNACLTNPCRNGGTC-DLLTLTEYKCRCPPGWSGKSCQQ-ADPCAS 146
C G+ G C +C +PC NGG+C + Y C CPP ++G +C++ D C S
Sbjct: 350 CPPGYYGLHC-EHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTS 408
Query: 147 NPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVC 206
NPCANGGQCL S +C C P F G C V++C + P C HGGTCH+ C C
Sbjct: 409 NPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNP--CAHGGTCHDLENGLMCTC 466
Query: 207 RATHTGPNCE--RPYVPCSPSPCQNGGTC-RPTGDVTHECACLPGFTGQNCE 255
A +G CE C+ SPC N TC T C C GF G CE
Sbjct: 467 PAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 48.9 bits (115), Expect = 6e-05
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ---DPNPCLSTPCKNAGTCHVVDRRGVADYAC 87
C +GG C C C F G RC+ + C S+PC N TC+ + C
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYT--DLSTDTFVC 506
Query: 88 SCALGFSGPLCLTPL 102
+C GF G C P+
Sbjct: 507 NCPYGFVGSRCEFPV 521
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 230 bits (586), Expect = 2e-59
Identities = 207/702 (29%), Positives = 272/702 (38%), Gaps = 172/702 (24%)
Query: 92 GFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA------DPCA 145
GF PLC C+ C + +C+C PGW G C P
Sbjct: 99 GFCVPLCA----QECVHGRC----------VAPNQCQCVPGWRGDDCSSECAPGMWGPQC 144
Query: 146 SNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGL---CR-HGGTCHNEVGS 201
PC+ G S +C CP P C Q P C+ HG C + G+
Sbjct: 145 DKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA 204
Query: 202 YRCVCRATHTGPNCERPYVPCS--------PS--PCQNGGTCR-PTGDVTHECACLPGFT 250
C C A TGP+C+ V CS PS CQNGG + P G C+C PG+
Sbjct: 205 --CFCPAERTGPSCD---VSCSQGTSGFFCPSTHSCQNGGVFQTPQG----SCSCPPGWM 255
Query: 251 GQNCEENIDDCP----GNNCK------NGGACVDGVNTYNCRCPPEWTGQYCTED----- 295
G C CP G NC NGG C T CRC P +TG C E+
Sbjct: 256 GTICSL---PCPEGFHGPNCSQECRCHNGGLC--DRFTGQCRCAPGYTGDRCREECPVGR 310
Query: 296 -----VDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI--DDCASAACFHGA 348
+ C P+A C +G C+C +G+TG+ C++ + D +C
Sbjct: 311 FGQDCAETCDCAPDA-----RCFPANGA--CLCEHGFTGDRCTDRLCPDGFYGLSCQAPC 363
Query: 349 TCHDRVASFYCECPHGRTGLL-----CHLNDACISNP----------CNEGSNCDTNPVN 393
TC DR S C +G L H N++C + C G C
Sbjct: 364 TC-DREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQAT--- 419
Query: 394 GKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGSFECQCLQGYTGPR 448
+C C GYTGP C+ + G N CE+A C G EC C +G+
Sbjct: 420 -SGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG--ECVCKEGWQRGN 476
Query: 449 CEIDVN------EC-VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNT------DECA 495
C + C S C ++A C Q G C C PG+ G HC++ + CA
Sbjct: 477 CSVPCPPGTWGFSCNASCQCAHEAVCSPQTG--ACTCTPGWHGAHCQLPCPKGQFGEGCA 534
Query: 496 S-SPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDE------CAST-PCKNGAKCLDGP 547
S C H+ C D ++ +C+C G+ G C E C++T CKNG CL P
Sbjct: 535 SRCDCDHSDGC-DPVHG-RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCL--P 590
Query: 548 NTYTCVCTEGYTGTHCEVDIDECDPDPCHYGS----CKDGVATF------TCLCRPGYTG 597
CVC G+ G C+ C P YG CK +F TC C G+TG
Sbjct: 591 ENGNCVCAPGFRGPSCQ---RSCQPG--RYGKRCVPCKCANHSFCHPSNGTCYCLAGWTG 645
Query: 598 HHCET-------NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDC----- 645
C N + C HGGTC +D + C C G TG +C L+ C
Sbjct: 646 PDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS--CICPLGWTGHHC---LEGCPLGTF 700
Query: 646 ---ASSPCDSG---TCLDKIDGYECACEPGYTGSMCNINIDE 681
S PC G C + C C PG++G+ C I I E
Sbjct: 701 GANCSQPCQCGPGEKCHPETGA--CVCPPGHSGAPCRIGIQE 740
Score = 226 bits (576), Expect = 2e-58
Identities = 202/724 (27%), Positives = 258/724 (35%), Gaps = 199/724 (27%)
Query: 321 CVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNP 380
C CV GW G+DCS EC G G C P
Sbjct: 120 CQCVPGWRGDDCSS-------------------------ECAPGMWGPQC-------DKP 147
Query: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCE-----HAGKCINTLGS 435
C+ G+N +P +G +C+CPSG P C Q G C+ H C G+
Sbjct: 148 CSCGNNSSCDPKSG--VCSCPSGLQPPNCLQPCTPGYYGP-ACQFRCQCHGAPCDPQTGA 204
Query: 436 FECQCLQGYTGPRCEIDVNECVS-------NPCQNDATCLDQIGEFQCICMPGYEGVHCE 488
C C TGP C++ ++ S + CQN Q + C C PG+ G C
Sbjct: 205 --CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVF--QTPQGSCSCPPGWMGTICS 260
Query: 489 VNTDE------CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDV------DECAST- 535
+ E C+ HNG D+ QC C G+TG C+ + +CA T
Sbjct: 261 LPCPEGFHGPNCSQECRCHNGGLCDRFTG-QCRCAPGYTGDRCREECPVGRFGQDCAETC 319
Query: 536 PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPD---------PC-----HYGSCK 581
C A+C P C+C G+TG C D PD PC H SC
Sbjct: 320 DCAPDARCF--PANGACLCEHGFTGDRCT---DRLCPDGFYGLSCQAPCTCDREHSLSCH 374
Query: 582 DGVATFTCLCRPGYTGHHCETNINECSSQP-------CRHGGTCQDRDNAYLCFCLKGTT 634
C C PG+ G HC + + + P C HGG CQ LC C G T
Sbjct: 375 P--MNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG--LCQCAPGYT 430
Query: 635 GPNCE-------INLDDCASSPCDSGTCLDKIDGYECACE-------------PGYTGSM 674
GP+C ++ A C++ IDG EC C+ PG G
Sbjct: 431 GPHCASLCPPDTYGVNCSARCSCENAIACSPIDG-ECVCKEGWQRGNCSVPCPPGTWGFS 489
Query: 675 CNINID---ECAGNPCHNGGTCEDGINGFTCR--CPEGYHDPTCLSEVNECNSNPC--VH 727
CN + E +P TC G +G C+ CP+G C S + +S+ C VH
Sbjct: 490 CNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVH 549
Query: 728 GACRDSLNGYKCDCDPGWSGTNCDINNNE------CESN-PCVNGGTCKDMTSGYVCTCR 780
G +C C GW G C ++ E C + C NGGTC C C
Sbjct: 550 G---------RCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGN--CVCA 598
Query: 781 EGFSGPNCQTNIN------ECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCA 834
GF GP+CQ + C C N C + C CL +TG C PC
Sbjct: 599 PGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HPSNGTCYCLAGWTGPDCS---QPCP 653
Query: 835 PS----------PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASC 884
P C +GG C + SC+CP GW G C G
Sbjct: 654 PGHWGENCAQTCQCHHGGTCHPQDG----SCICPLGWTGHH------------CLEG--- 694
Query: 885 QNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEE 944
C G G NC +P C G C T C C PG G C
Sbjct: 695 ----------CPLGTFGANCS------QPCQCGPGEKCHP--ETGACVCPPGHSGAPCRI 736
Query: 945 DINE 948
I E
Sbjct: 737 GIQE 740
Score = 224 bits (571), Expect = 8e-58
Identities = 224/835 (26%), Positives = 291/835 (34%), Gaps = 245/835 (29%)
Query: 707 GYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGG 766
G+ P C E CVHG C + +C C PGW G ++C S
Sbjct: 99 GFCVPLCAQE--------CVHGRC---VAPNQCQCVPGWRG-------DDCSSE------ 134
Query: 767 TCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATC 826
C G GP C C+ C N +C D C+C C
Sbjct: 135 ------------CAPGMWGPQCD---KPCS---CGNNSSC--DPKSGVCSCPSGLQPPNC 174
Query: 827 EVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQN 886
L PC P G C+ F C C G C+ C R G SC
Sbjct: 175 ---LQPCTPG--YYGPACQ-------FRCQC----HGAPCDPQTGACFCPAERTGPSCDV 218
Query: 887 THGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDI 946
+ C G SG C + + C NGG + C C PG+ GT C
Sbjct: 219 S-------CSQGTSGFFCPST------HSCQNGGVFQTPQGS--CSCPPGWMGTIC---- 259
Query: 947 NECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFT 1006
+ CP GF G +C E C NGG C + FT
Sbjct: 260 ---------------------SLPCPEGFHGPNCSQ------ECRCHNGGLC----DRFT 288
Query: 1007 --CLCPPGFTGSYCQHD----------VNECDSQP---CLHGG---TCQDGCGSYRCT-- 1046
C C PG+TG C+ + CD P C C+ G RCT
Sbjct: 289 GQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDR 348
Query: 1047 -CPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHT------QYRCECPSGWTGLYCDVPSV 1099
CP G+ G +CQ +PC C + H+ C C GW GL+C+
Sbjct: 349 LCPDGFYGLSCQ--------APCT----CDREHSLSCHPMNGECSCLPGWAGLHCNE--- 393
Query: 1100 SCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGAT 1159
SC G LC HGG+C C+C GYTG +C L C P G
Sbjct: 394 SCPQDTHGPGCQEHCLCLHGGVCQATSGL--CQCAPGYTGPHCASL---CPPDTY--GVN 446
Query: 1160 CTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCE 1219
C+ C C + + CS EC+ G C CP GT G C
Sbjct: 447 CSA-----RCSCE---NAIACSPIDGECVCKEGWQRGNC-------SVPCPPGTWGFSC- 490
Query: 1220 INVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----GDVNECLSN 1274
+ S +C + C Q G +CTC PG+ G C+ G E ++
Sbjct: 491 -------------NASCQCAHEAVCSPQTG--ACTCTPGWHGAHCQLPCPKGQFGEGCAS 535
Query: 1275 PCDARGTQNCVQRVNDFH--CECRAGHTGRRCESV-------INGCKGKPCKNGGTCAVA 1325
CD + C + H C+C+AG G RC +N CKNGGTC
Sbjct: 536 RCDCDHSDGC----DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPE 591
Query: 1326 SNTARGFICKCPAGFEGATCENDA------RTCGSLRCLNGGTCISGPRSPTCLCLGPFT 1379
+ C C GF G +C+ + C +C N C P + TC CL +T
Sbjct: 592 NGN-----CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HPSNGTCYCLAGWT 644
Query: 1380 GPECQFPASSPCLGGN-----PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGG 1434
GP+C P G N C++ GTC P S C+CP + G H L+ G
Sbjct: 645 GPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS----CICPLGWTG--HHCLEGCPLG 698
Query: 1435 GAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHAC--GWDGGDCSLNFNDPW 1487
G + P CQ G K C + C G G C + +P+
Sbjct: 699 TFGANCSQP----------CQCGPGEK-CHPETGACVCPPGHSGAPCRIGIQEPF 742
Score = 217 bits (552), Expect = 1e-55
Identities = 180/635 (28%), Positives = 245/635 (38%), Gaps = 121/635 (19%)
Query: 21 GPRCSQPGETCLNGGKCEAANGTEACV-----------CGGAFVGPRCQDPNPCLSTPCK 69
GP+C +P +C N C+ +G +C C + GP CQ C PC
Sbjct: 141 GPQCDKPC-SCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCD 199
Query: 70 -NAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCR 128
G C R SC+ G SG C + T+ C+NGG + + C
Sbjct: 200 PQTGACFCPAERTGPSCDVSCSQGTSGFFCPS-------THSCQNGG---VFQTPQGSCS 249
Query: 129 CPPGWSGKSCQQADP-------CASN-PCANGGQCLPFEASYICHCPPSFHGPTCRQD-- 178
CPPGW G C P C+ C NGG C F C C P + G CR++
Sbjct: 250 CPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQ--CRCAPGYTGDRCREECP 307
Query: 179 VNECGQKPGL---CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP------CSPSPC-- 227
V GQ C C G+ C+C TG C P +PC
Sbjct: 308 VGRFGQDCAETCDCAPDARCFPANGA--CLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
Query: 228 --QNGGTCRPTGDVTHECACLPGFTGQNCEENI-DDCPGNNCKNGGACVDG----VNTYN 280
++ +C P + EC+CLPG+ G +C E+ D G C+ C+ G +
Sbjct: 366 DREHSLSCHP---MNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGL 422
Query: 281 CRCPPEWTGQYCTEDVDECQLMPN-----ACQNGGTCHNTHGGYNCVCVNGWTGEDCSEN 335
C+C P +TG +C N +C+N C G CVC GW +CS
Sbjct: 423 CQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG--ECVCKEGWQRGNCSVP 480
Query: 336 ID------DC-ASAACFHGATCHDRVASFYCECPHGRTGLLCHL-------NDACISN-P 380
C AS C H A C + + C C G G C L + C S
Sbjct: 481 CPPGTWGFSCNASCQCAHEAVCSPQTGA--CTCTPGWHGAHCQLPCPKGQFGEGCASRCD 538
Query: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGS 435
C+ CD PV+G+ C C +G+ G C E G N C++ G C+ G+
Sbjct: 539 CDHSDGCD--PVHGR--CQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGN 594
Query: 436 FECQCLQGYTGPRCEIDVN------ECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEV 489
C C G+ GP C+ CV C N + C G C C+ G+ G C
Sbjct: 595 --CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGT--CYCLAGWTGPDCSQ 650
Query: 490 NT------DECASS-PCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDEC--------AS 534
+ CA + C H G C + + C CP G+TGH C ++ C S
Sbjct: 651 PCPPGHWGENCAQTCQCHHGGTCHPQ--DGSCICPLGWTGHHC---LEGCPLGTFGANCS 705
Query: 535 TPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
PC+ G P T CVC G++G C + I E
Sbjct: 706 QPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQE 740
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 227 bits (578), Expect = 1e-58
Identities = 174/610 (28%), Positives = 240/610 (39%), Gaps = 105/610 (17%)
Query: 279 YNCRCPPEWTGQYCTEDVDECQL-MPNACQNGGTCHNTH-GGYNCVCVNGWTGEDCSENI 336
+ C+ PP Q +C L + + CQN GTCHN Y C C +G+ G DC ++
Sbjct: 912 FECQGPPTLAVQA------KCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSL 965
Query: 337 DDCASAACFHGATCHDRV---ASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPV 392
D C+S C +G TCH + A F C CP G G C +N D C+ + C G C
Sbjct: 966 DSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGV- 1024
Query: 393 NGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEID 452
G C CP Y G AC Q VD CS NPC+H +C+ T C+C+ GY G C +
Sbjct: 1025 -GNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN 1083
Query: 453 VNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEV------NTDECASSPCLHNGRCL 506
++C + CQN A C+D++ + C+C GY G CE+ C + C + C+
Sbjct: 1084 QDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCV 1143
Query: 507 DKINEFQCECPTGFTGHLCQ------------------------YDVDECASTPCKNGAK 542
D+ N C+C GF G C+ ++ ST NG
Sbjct: 1144 DQGNRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGIL 1203
Query: 543 CLDGPNTYTCVCTEGYTGTHCEVDIDECD-PDPCHYG--SCKDG------VATFTCLCRP 593
+G N + + E Y G H V D P Y + DG + F +
Sbjct: 1204 LYNGDNDH--IAVELYQG-HVRVSYDPGSYPSSAIYSAETINDGQFHTVELVAFDQMVNL 1260
Query: 594 GYTGHHCETNIN------ECSSQPCRHGGTCQDRDNA--YLCFCLKGTTGPNCEINL--- 642
G T N S P GG D ++A L L GT C NL
Sbjct: 1261 SIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYIN 1320
Query: 643 -------------------DDCASSPCDSGTCL-DKIDGYECACEPGYTGSMCNINID-E 681
+ C C G C + G C CE G+ G C+ D
Sbjct: 1321 NELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGP 1380
Query: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSE---VNECNSNPCVHGACRDS-LNGY 737
C G+ C +G ++C+C +GY C C C+HG C+ S G
Sbjct: 1381 CHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGA 1440
Query: 738 KCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINECA 796
C CDPG+SG C+ +EC +P + + GY +C S C+
Sbjct: 1441 HCVCDPGFSGELCE-QESECRGDPVRD---FHQVQRGYAICQTTRPLSWVECR------- 1489
Query: 797 SNPCLNQGTC 806
C QG C
Sbjct: 1490 -GSCPGQGCC 1498
Score = 207 bits (528), Expect = 8e-53
Identities = 160/569 (28%), Positives = 228/569 (40%), Gaps = 79/569 (13%)
Query: 473 EFQCICMPGYEGVHCEVNTDECASSPCLHNGRCL-DKINEFQCECPTGFTGHLCQYDVDE 531
+F+C G + + D C SSPC + G C D + ++C CP+G+ G C+ +D
Sbjct: 911 KFEC---QGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS 967
Query: 532 CASTPCKNGAKCL-----DGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGS-CKDGVA 585
C+S PC+NG C D P +TC C G+ G C V+ D+C C G C DGV
Sbjct: 968 CSSGPCENGGTCHAQEGEDAP--FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVG 1025
Query: 586 TFTCLCRPGYTGHHCETNINECSSQ--PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLD 643
+TC C Y G CE ++ CS PC+H C + C C+ G G NC N D
Sbjct: 1026 NYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQD 1085
Query: 644 DCASSPCDSGT-CLDKIDGYECACEPGYTGSMCNINI------DECAGNPCHNGGTCEDG 696
DC C +G C+D+++ Y C C GY+G +C I C G C NG C D
Sbjct: 1086 DCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQ 1145
Query: 697 INGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNE 756
N C+C G+ P EC V+ RD+ + D W N + +
Sbjct: 1146 GNRPVCQCLPGFGGP-------ECEKLLSVNFVDRDTYLQFT-DLQ-NWPRANITLQVST 1196
Query: 757 CESNPCV-----NGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLN--QGTCIDD 809
E N + N ++ G+V + S P+ E ++ + + D
Sbjct: 1197 AEDNGILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQFHTVELVAFDQ 1256
Query: 810 VAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ--SEDYESFSCVCPTGWQGQTCE 867
+ + P T + +P GG S + + + TG+ G
Sbjct: 1257 MVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRN 1316
Query: 868 VDINECV---------------LSPCR-----HGASCQNTHGGYRCHCQAGYSGRNCETD 907
+ IN + PCR HG N G CHC+AG+ G +C+
Sbjct: 1317 LYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQP 1376
Query: 908 IDDCRPNPCHNGGSCTDG------INTAFCDCLPGFRGTFCEEDINECASDPCRNGANCT 961
D PCH G C G + C C G+ G C + ++PCR G C
Sbjct: 1377 AD----GPCH-GHKCVHGQCVPLDALSYSCQCQDGYSGALCNQ--AGALAEPCR-GLQCL 1428
Query: 962 --DCVDSYT----CTCPAGFSGIHCENNT 984
C S T C C GFSG CE +
Sbjct: 1429 HGHCQASGTKGAHCVCDPGFSGELCEQES 1457
Score = 204 bits (518), Expect = 1e-51
Identities = 109/271 (40%), Positives = 133/271 (49%), Gaps = 29/271 (10%)
Query: 1005 FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQ-DGCGSYRCTCPQGYTGPNCQNLVHWC 1063
F C PP Q + C S PC + GTC D YRC CP GY G +C+ + C
Sbjct: 912 FECQGPPTLA---VQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSC 968
Query: 1064 DSSPCKNGGKCWQTHTQ---YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGG 1120
S PC+NGG C + + C CP+G+ G C V + C V C +GG
Sbjct: 969 SSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC----------VDHACANGG 1018
Query: 1121 LCVDAGNTHHCRCQAGYTGSYCEDLVDECSP--SPCQNGATCTDYLGGYSCKCVAGYHGV 1178
+CVD + C+C Y G CE LVD CSP +PCQ+ A C G C+C+ GY G
Sbjct: 1019 VCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGD 1078
Query: 1179 NCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSP-- 1236
NCSE D+C H CQNG C+D N+Y C C G G CEI PP P +SP
Sbjct: 1079 NCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEI------PPHLPAPKSPCE 1132
Query: 1237 --KCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
+C N CVDQ C C PGF G CE
Sbjct: 1133 GTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 202 bits (515), Expect = 3e-51
Identities = 97/241 (40%), Positives = 129/241 (53%), Gaps = 10/241 (4%)
Query: 789 QTNINECASNPCLNQGTCIDD-VAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
Q + C S+PC NQGTC +D + Y+C C Y G CEV L C+ PC NGG C
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 982
Query: 848 EDYES-FSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCET 906
E ++ F+C CPTG++G TC V+ ++CV C +G C + G Y C C Y G+ CE
Sbjct: 983 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQ 1042
Query: 907 DIDDCRP--NPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCV 964
+D C P NPC + C + C+C+PG+ G C E+ ++C C+NGA C D V
Sbjct: 1043 LVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEV 1102
Query: 965 DSYTCTCPAGFSGIHCE------NNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
+SY+C C G+SG CE C + C NG CVD N C C PGF G C
Sbjct: 1103 NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPEC 1162
Query: 1019 Q 1019
+
Sbjct: 1163 E 1163
Score = 196 bits (499), Expect = 2e-49
Identities = 97/258 (37%), Positives = 129/258 (50%), Gaps = 17/258 (6%)
Query: 164 CHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNE-VGSYRCVCRATHTGPNCERPYVPC 222
C PP+ + + C P C++ GTCHN+ + YRC C + + G +CE C
Sbjct: 914 CQGPPTL---AVQAKCDLCLSSP--CQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSC 968
Query: 223 SPSPCQNGGTCRPTG--DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280
S PC+NGGTC D C+C GF G C N DDC + C NGG CVDGV Y
Sbjct: 969 SSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYT 1028
Query: 281 CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340
C+CP ++ G+ C + VD C N CQ+ C T G C C+ G+ G++CSEN DDC
Sbjct: 1029 CQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR 1088
Query: 341 SAACFHGATCHDRVASFYCECPHGRTGLLCHL-------NDACISNPCNEGSNCDTNPVN 393
C +GA C D V S+ C C G +G LC + C C G+NC
Sbjct: 1089 DHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQ--G 1146
Query: 394 GKAICTCPSGYTGPACSQ 411
+ +C C G+ GP C +
Sbjct: 1147 NRPVCQCLPGFGGPECEK 1164
Score = 191 bits (484), Expect = 1e-47
Identities = 99/270 (36%), Positives = 134/270 (49%), Gaps = 15/270 (5%)
Query: 420 ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL-DQIGEFQCIC 478
A P + GK + T + + +C QG + + C+S+PCQN TC D + ++C C
Sbjct: 894 AGPQDMEGKLLLTTPAKKFEC-QGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCAC 952
Query: 479 MPGYEGVHCEVNTDECASSPCLHNGRCLDKINE---FQCECPTGFTGHLCQYDVDECAST 535
GY+G CEV+ D C+S PC + G C + E F C CPTGF G C + D+C
Sbjct: 953 PSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDH 1012
Query: 536 PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPD--PC-HYGSCKDGVATFTCLCR 592
C NG C+DG YTC C Y G CE +D C PD PC H C C C
Sbjct: 1013 ACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECM 1072
Query: 593 PGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI------NLDDCA 646
PGY G +C N ++C C++G C D N+Y C C +G +G CEI C
Sbjct: 1073 PGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCE 1132
Query: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMC 675
+ C +G C+D+ + C C PG+ G C
Sbjct: 1133 GTECQNGANCVDQGNRPVCQCLPGFGGPEC 1162
Score = 190 bits (482), Expect = 2e-47
Identities = 91/244 (37%), Positives = 124/244 (50%), Gaps = 10/244 (4%)
Query: 909 DDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC--TDCVD 965
D C +PC N G+C D + C C G++G CE ++ C+S PC NG C + D
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 966 S-YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE 1024
+ +TC+CP GF G C NT DC + +C NGG CVDG+ ++TC CP + G C+ V+
Sbjct: 987 APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDL 1046
Query: 1025 C--DSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1082
C D PC H C RC C GY G NC C C+NG +C Y
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106
Query: 1083 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYC 1142
C C G++G C++P + +G + CQ+G CVD GN C+C G+ G C
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTE----CQNGANCVDQGNRPVCQCLPGFGGPEC 1162
Query: 1143 EDLV 1146
E L+
Sbjct: 1163 EKLL 1166
Score = 188 bits (478), Expect = 5e-47
Identities = 95/265 (35%), Positives = 136/265 (51%), Gaps = 17/265 (6%)
Query: 392 VNGKAICTCPSGY---TGPACSQDVDECSLG-ANPCEHAGKCINT-LGSFECQCLQGYTG 446
+ GK + T P+ GP +C L ++PC++ G C N L + C C GY G
Sbjct: 899 MEGKLLLTTPAKKFECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKG 958
Query: 447 PRCEIDVNECVSNPCQNDATCLDQIGE---FQCICMPGYEGVHCEVNTDECASSPCLHNG 503
CE+ ++ C S PC+N TC Q GE F C C G+EG C VNTD+C C + G
Sbjct: 959 RDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGG 1018
Query: 504 RCLDKINEFQCECPTGFTGHLCQYDVDECAS--TPCKNGAKCLDGPNTYTCVCTEGYTGT 561
C+D + + C+CP + G C+ VD C+ PC++ A+C+ P+ C C GY G
Sbjct: 1019 VCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGD 1078
Query: 562 HCEVDIDECDPDPCHYGS-CKDGVATFTCLCRPGYTGHHCE------TNINECSSQPCRH 614
+C + D+C C G+ C D V +++CLC GY+G CE + C C++
Sbjct: 1079 NCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQN 1138
Query: 615 GGTCQDRDNAYLCFCLKGTTGPNCE 639
G C D+ N +C CL G GP CE
Sbjct: 1139 GANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 177 bits (450), Expect = 9e-44
Identities = 89/246 (36%), Positives = 120/246 (48%), Gaps = 22/246 (8%)
Query: 949 CASDPCRNGANC-TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC--VDGINS- 1004
C S PC+N C D ++ Y C CP+G+ G CE + C+ C NGGTC +G ++
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988
Query: 1005 FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWC- 1063
FTC CP GF G C + ++C C +GG C DG G+Y C CP Y G C+ LV C
Sbjct: 989 FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS 1048
Query: 1064 -DSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
D +PC++ +C T RCEC G+ G C C CQ+G C
Sbjct: 1049 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR----------DHRCQNGAQC 1098
Query: 1123 VDAGNTHHCRCQAGYTGSYCE------DLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH 1176
+D N++ C C GY+G CE C + CQNGA C D C+C+ G+
Sbjct: 1099 MDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFG 1158
Query: 1177 GVNCSE 1182
G C +
Sbjct: 1159 GPECEK 1164
Score = 176 bits (447), Expect = 2e-43
Identities = 98/252 (38%), Positives = 118/252 (46%), Gaps = 29/252 (11%)
Query: 1147 DECSPSPCQNGATC-TDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCL-----D 1200
D C SPCQN TC D L Y C C +GY G +C +D C S PC+NGGTC D
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 1201 LPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV 1260
P T CSCP G +G C +N DDC VD C N G CVD VG Y+C CP +
Sbjct: 987 APFT--CSCPTGFEGPTCGVNTDDC---VDHA-----CANGGVCVDGVGNYTCQCPLQYE 1036
Query: 1261 GERCEGDVNECLS--NPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 1318
G+ CE V+ C NPC CV + CEC G+ G C + C+ C+N
Sbjct: 1037 GKACEQLVDLCSPDLNPCQHEA--QCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQN 1094
Query: 1319 GGTCAVASNTARGFICKCPAGFEGATCE------NDARTCGSLRCLNGGTCISGPRSPTC 1372
G C N+ + C C G+ G CE C C NG C+ P C
Sbjct: 1095 GAQCMDEVNS---YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVC 1151
Query: 1373 LCLGPFTGPECQ 1384
CL F GPEC+
Sbjct: 1152 QCLPGFGGPECE 1163
Score = 166 bits (419), Expect = 4e-40
Identities = 85/239 (35%), Positives = 111/239 (46%), Gaps = 14/239 (5%)
Query: 63 CLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTL 122
CLS+PC+N GTCH + Y C+C G+ G C LD+ C + PC NGGTC
Sbjct: 929 CLSSPCQNQGTCH---NDPLEVYRCACPSGYKGRDCEVSLDS-CSSGPCENGGTCHAQEG 984
Query: 123 TE--YKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDV 179
+ + C CP G+ G +C D C + CANGG C+ +Y C CP + G C Q V
Sbjct: 985 EDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLV 1044
Query: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV 239
+ C C+H C RC C + G NC C CQNG C +
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVN- 1103
Query: 240 THECACLPGFTGQNCE------ENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC 292
++ C C G++GQ CE C G C+NG CVD N C+C P + G C
Sbjct: 1104 SYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPEC 1162
Score = 160 bits (404), Expect = 2e-38
Identities = 116/395 (29%), Positives = 159/395 (40%), Gaps = 54/395 (13%)
Query: 946 INECASDPCRNGANCTDCVDSYT---CTCPAGFSGIHC------ENNTPDCTESSCFNGG 996
I+ ++ N + T + SY C P F G+ N + F
Sbjct: 796 ISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADV 855
Query: 997 TCVD----GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCP---- 1048
T + G N C C + S+ + E C QD G T P
Sbjct: 856 TSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGP---QDMEGKLLLTTPAKKF 912
Query: 1049 --QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ-YRCECPSGWTGLYCDVPSVSCEVAA 1105
QG Q C SSPC+N G C + YRC CPSG+ G C+V SC
Sbjct: 913 ECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGP 972
Query: 1106 QRQGVDVARLCQHGGLC-----VDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC 1160
C++GG C DA T C C G+ G C D+C C NG C
Sbjct: 973 ----------CENGGTCHAQEGEDAPFT--CSCPTGFEGPTCGVNTDDCVDHACANGGVC 1020
Query: 1161 TDYLGGYSCKCVAGYHGVNCSEEIDECLS--HPCQNGGTCLDLPNTYKCSCPRGTQGVHC 1218
D +G Y+C+C Y G C + +D C +PCQ+ C+ P+ +C C G G +C
Sbjct: 1021 VDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNC 1080
Query: 1219 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVN-ECLSNPCD 1277
N DDC R +C N C+D+V YSC C G+ G+ CE + +PC+
Sbjct: 1081 SENQDDC--------RDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCE 1132
Query: 1278 ARGTQN---CVQRVNDFHCECRAGHTGRRCESVIN 1309
QN CV + N C+C G G CE +++
Sbjct: 1133 GTECQNGANCVDQGNRPVCQCLPGFGGPECEKLLS 1167
Score = 137 bits (346), Expect = 1e-31
Identities = 79/259 (30%), Positives = 114/259 (44%), Gaps = 53/259 (20%)
Query: 124 EYKCRCPPGWSGKSCQQADPCASNPCANGGQCL--PFE---------------------- 159
+++C+ PP + ++ + D C S+PC N G C P E
Sbjct: 911 KFECQGPPTLAVQA--KCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSC 968
Query: 160 ------------------ASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGS 201
A + C CP F GPTC + ++C C +GG C + VG+
Sbjct: 969 SSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDH--ACANGGVCVDGVGN 1026
Query: 202 YRCVCRATHTGPNCERPYVPCSP--SPCQNGGTCRPTGDVTHECACLPGFTGQNCEENID 259
Y C C + G CE+ CSP +PCQ+ C T D C C+PG+ G NC EN D
Sbjct: 1027 YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPD-GPRCECMPGYAGDNCSENQD 1085
Query: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCT----EDVDECQLMPNACQNGGTCHNT 315
DC + C+NG C+D VN+Y+C C ++GQ C + CQNG C +
Sbjct: 1086 DCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQ 1145
Query: 316 HGGYNCVCVNGWTGEDCSE 334
C C+ G+ G +C +
Sbjct: 1146 GNRPVCQCLPGFGGPECEK 1164
Score = 120 bits (302), Expect = 1e-26
Identities = 86/284 (30%), Positives = 114/284 (40%), Gaps = 72/284 (25%)
Query: 1251 YSCTCPPGF-VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVIN 1309
+ C PP V +C+ CLS+PC +GT + + + C C +G+ GR CE ++
Sbjct: 912 FECQGPPTLAVQAKCD----LCLSSPCQNQGTCHN-DPLEVYRCACPSGYKGRDCEVSLD 966
Query: 1310 GCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRS 1369
C PC+NGGTC F C CP GFEG TC + C C NGG C+ G +
Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1026
Query: 1370 PTCLCLGPFTGPECQ--FPASSPCLGGNPCYNQGTCEPTSESP----------------- 1410
TC C + G C+ SP L NPC ++ C T + P
Sbjct: 1027 YTCQCPLQYEGKACEQLVDLCSPDL--NPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQ 1084
Query: 1411 -------------------FYRCLCPAKFNGLLCHILDYSFGGGAGRDIPP--PLIEEAC 1449
Y CLC ++G LC +IPP P + C
Sbjct: 1085 DDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLC-------------EIPPHLPAPKSPC 1131
Query: 1450 ELPECQEDAGNKVCSLQCNNHAC----GWDGGDC----SLNFND 1485
E ECQ A C Q N C G+ G +C S+NF D
Sbjct: 1132 EGTECQNGAN---CVDQGNRPVCQCLPGFGGPECEKLLSVNFVD 1172
Score = 105 bits (261), Expect = 7e-22
Identities = 65/198 (32%), Positives = 89/198 (44%), Gaps = 17/198 (8%)
Query: 31 CLNGGKCEAANGTEA---CVCGGAFVGPRC-QDPNPCLSTPCKNAGTCHVVDRRGVADYA 86
C NGG C A G +A C C F GP C + + C+ C N G C VD GV +Y
Sbjct: 973 CENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVC--VD--GVGNYT 1028
Query: 87 CSCALGFSGPLCLTPLDNACL--TNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC-QQADP 143
C C L + G C L + C NPC++ C + T +C C PG++G +C + D
Sbjct: 1029 CQCPLQYEGKAC-EQLVDLCSPDLNPCQHEAQC-VGTPDGPRCECMPGYAGDNCSENQDD 1086
Query: 144 CASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGL----CRHGGTCHNEV 199
C + C NG QC+ SY C C + G C + K C++G C ++
Sbjct: 1087 CRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQG 1146
Query: 200 GSYRCVCRATHTGPNCER 217
C C GP CE+
Sbjct: 1147 NRPVCQCLPGFGGPECEK 1164
Score = 66.2 bits (160), Expect = 4e-10
Identities = 57/215 (26%), Positives = 82/215 (38%), Gaps = 25/215 (11%)
Query: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEID-ECLSHPCQNGGTCLDLPN-T 1204
+ C C +G + G C C AG+ G++C + D C H C +G C+ L +
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALS 1398
Query: 1205 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERC 1264
Y C C G G C + +P R +C + G C C PGF GE C
Sbjct: 1399 YSCQCQDGYSGALC----NQAGALAEPC-RGLQCLHGHCQASGTKGAHCVCDPGFSGELC 1453
Query: 1265 EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVIN--GCKGKPCKNGGTC 1322
E + +EC +P V DFH + + G+ + ++ C+G C G C
Sbjct: 1454 EQE-SECRGDP------------VRDFH-QVQRGYAICQTTRPLSWVECRGS-CPGQGCC 1498
Query: 1323 AVASNTARGFICKCPAGFEGATCENDARTCGSLRC 1357
R F +C G A CG C
Sbjct: 1499 QGLRLKRRKFTFECSDGTSFAEEVEKPTKCGCALC 1533
Score = 65.5 bits (158), Expect = 7e-10
Identities = 53/194 (27%), Positives = 73/194 (37%), Gaps = 47/194 (24%)
Query: 720 CNSNPCVHGACRDSLN-GYKCDCDPGWSGTNCDIN-NNECESNPCVNGGTCKDMTSGYVC 777
C C+HG C+ + G C C+ GW G +CD + C + CV+G Y C
Sbjct: 1342 CRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSC 1401
Query: 778 TCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSP 837
C++G+SG C NQ GA E PC
Sbjct: 1402 QCQDGYSGALC-------------NQ------------------AGALAE----PCRGLQ 1426
Query: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRH-------GASCQNTHGG 890
C + G C Q+ + CVC G+ G+ CE + +EC P R A CQ T
Sbjct: 1427 CLH-GHC-QASGTKGAHCVCDPGFSGELCEQE-SECRGDPVRDFHQVQRGYAICQTTRPL 1483
Query: 891 YRCHCQAGYSGRNC 904
C+ G+ C
Sbjct: 1484 SWVECRGSCPGQGC 1497
Score = 60.8 bits (146), Expect = 2e-08
Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 13/115 (11%)
Query: 1083 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYC 1142
C C +GW GL+CD P+ G C HG ++ C+CQ GY+G+ C
Sbjct: 1362 CHCEAGWVGLHCDQPA---------DGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1412
Query: 1143 ED---LVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQN 1194
L + C C +G G C C G+ G C +E EC P ++
Sbjct: 1413 NQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-SECRGDPVRD 1466
Score = 60.5 bits (145), Expect = 2e-08
Identities = 40/124 (32%), Positives = 50/124 (40%), Gaps = 13/124 (10%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDP--NPCLSTPCKNAGTCHVVDRRGVADYACS 88
CL+G A C C +VG C P PC C + G C +D Y+C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLD---ALSYSCQ 1402
Query: 89 CALGFSGPLCLTPLDNACLTNPCRN----GGTCDLLTLTEYKCRCPPGWSGKSCQQADPC 144
C G+SG LC L PCR G C C C PG+SG+ C+Q C
Sbjct: 1403 CQDGYSGALCNQA---GALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESEC 1459
Query: 145 ASNP 148
+P
Sbjct: 1460 RGDP 1463
Score = 59.7 bits (143), Expect = 4e-08
Identities = 47/184 (25%), Positives = 68/184 (36%), Gaps = 20/184 (10%)
Query: 909 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCT--DCVD- 965
+ CR C +G + C C G+ G C++ A PC +G C CV
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQP----ADGPC-HGHKCVHGQCVPL 1394
Query: 966 ---SYTCTCPAGFSGIHCENN---TPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ 1019
SY+C C G+SG C C C +G G C+C PGF+G C+
Sbjct: 1395 DALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
Query: 1020 HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHT 1079
+ +EC P Q G + T P + C+ C C G + +
Sbjct: 1455 QE-SECRGDPVRDFHQVQRGYAICQTTRPLSWV--ECRGS---CPGQGCCQGLRLKRRKF 1508
Query: 1080 QYRC 1083
+ C
Sbjct: 1509 TFEC 1512
Score = 58.5 bits (140), Expect = 8e-08
Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 16/127 (12%)
Query: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVING-CKGKPCKNGGTCAVASNTA 1329
CL C T + C C AG G C+ +G C G C +G + A
Sbjct: 1347 CLHGICQPNATPGPM-------CHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPL---DA 1396
Query: 1330 RGFICKCPAGFEGATCEND---ARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFP 1386
+ C+C G+ GA C A C L+CL+G SG + C+C F+G C+
Sbjct: 1397 LSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCE-- 1454
Query: 1387 ASSPCLG 1393
S C G
Sbjct: 1455 QESECRG 1461
Score = 58.2 bits (139), Expect = 1e-07
Identities = 63/250 (25%), Positives = 92/250 (36%), Gaps = 36/250 (14%)
Query: 104 NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEA-SY 162
+ C+ N N D T T+ K PG +PC C +G C P
Sbjct: 1311 HGCIRNLYINNELQDF-TKTQMKPGVVPG--------CEPCRKLYCLHG-ICQPNATPGP 1360
Query: 163 ICHCPPSFHGPTCRQDVN-EC-GQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYV 220
+CHC + G C Q + C G K C HG + SY C C+ ++G C +
Sbjct: 1361 MCHCEAGWVGLHCDQPADGPCHGHK---CVHGQCVPLDALSYSCQCQDGYSGALCNQAGA 1417
Query: 221 ---PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVN 277
PC C +G C+ +G C C PGF+G+ CE+ +C G+ ++ G
Sbjct: 1418 LAEPCRGLQCLHGH-CQASGTKGAHCVCDPGFSGELCEQE-SECRGDPVRDFHQVQRGYA 1475
Query: 278 TYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHN---THGGYNCVCVNGWTGEDCSE 334
P W EC+ +C G C + C +G + + E
Sbjct: 1476 ICQTTRPLSWV---------ECR---GSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVE 1523
Query: 335 NIDDCASAAC 344
C A C
Sbjct: 1524 KPTKCGCALC 1533
Score = 52.4 bits (124), Expect = 6e-06
Identities = 43/179 (24%), Positives = 58/179 (32%), Gaps = 47/179 (26%)
Query: 281 CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHN---THG--------GYNCVCVNGWTG 329
C C W G +C + D G CH HG Y+C C +G++G
Sbjct: 1362 CHCEAGWVGLHCDQPAD------------GPCHGHKCVHGQCVPLDALSYSCQCQDGYSG 1409
Query: 330 EDCSEN---IDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSN 386
C++ + C C HG +C C G +G LC C +P +
Sbjct: 1410 ALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRGDPVRDFHQ 1469
Query: 387 CDTNPVNGKAIC---------TCPSGYTGPACSQDVD--------ECSLGANPCEHAGK 428
G AIC C G C Q + ECS G + E K
Sbjct: 1470 VQ----RGYAICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEK 1524
Score = 49.7 bits (117), Expect = 4e-05
Identities = 52/200 (26%), Positives = 71/200 (35%), Gaps = 37/200 (18%)
Query: 337 DDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKA 396
+ C C HG + C C G GL C D PC+ G C V+G+
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHC---DQPADGPCH-GHKC----VHGQC 1391
Query: 397 I--------CTCPSGYTGPACSQDVDECSLGANPCEHA----GKC--INTLGSFECQCLQ 442
+ C C GY+G C+Q A PC G C T G+ C C
Sbjct: 1392 VPLDALSYSCQCQDGYSGALCNQ----AGALAEPCRGLQCLHGHCQASGTKGA-HCVCDP 1446
Query: 443 GYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP--GYEGVHCEVNTDECASSPCL 500
G++G CE + +EC +P ++ Q+ IC V C C C
Sbjct: 1447 GFSGELCEQE-SECRGDPVRD----FHQVQRGYAICQTTRPLSWVECR---GSCPGQGCC 1498
Query: 501 HNGRCLDKINEFQCECPTGF 520
R + F+C T F
Sbjct: 1499 QGLRLKRRKFTFECSDGTSF 1518
Score = 43.9 bits (102), Expect = 0.002
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 1352 CGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPF 1411
C L CL+G + P C C + G C PA PC G+ C + G C P ++
Sbjct: 1342 CRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPC-HGHKCVH-GQCVPL-DALS 1398
Query: 1412 YRCLCPAKFNGLLCH 1426
Y C C ++G LC+
Sbjct: 1399 YSCQCQDGYSGALCN 1413
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 221 bits (563), Expect = 7e-57
Identities = 176/583 (30%), Positives = 240/583 (41%), Gaps = 112/583 (19%)
Query: 98 CLTPLDNACLTNP-CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCL 156
CL P T P C G + C C PGW G +C + + C N C G+C+
Sbjct: 147 CLQPATGRLDTRPFCSGRGN---FSTEGCGCVCEPGWKGPNCSEPE-CPGN-CHLRGRCI 201
Query: 157 PFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCE 216
+ C C F G C Q C P C G C N V C+C + G +C
Sbjct: 202 DGQ----CICDDGFTGEDCSQ--LAC---PSDCNDQGKCVNGV----CICFEGYAGADCS 248
Query: 217 RPY--VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVD 274
R VPCS + GTC V C C GF G +C + + C NNC N G CV+
Sbjct: 249 REICPVPCS----EEHGTC-----VDGLCVCHDGFAGDDCNKPL--CL-NNCYNRGRCVE 296
Query: 275 GVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSE 334
C C +TG+ C+E + PN C + G C N C C G+TGEDC +
Sbjct: 297 N----ECVCDEGFTGEDCSE-----LICPNDCFDRGRCING----TCYCEEGFTGEDCGK 343
Query: 335 NIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNG 394
C H R C C G G+ C ++ C+ C V+G
Sbjct: 344 -------PTCPHACHTQGRCEEGQCVCDEGFAGVDC--SEKRCPADCHNRGRC----VDG 390
Query: 395 KAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVN 454
+ C C G+TG C + +C N C G+C+N +C C +GYTG
Sbjct: 391 R--CECDDGFTGADCGE--LKC---PNGCSGHGRCVNG----QCVCDEGYTG-------E 432
Query: 455 ECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQC 514
+C C ND + E +C+C G++G C +D + C +GRC++ + C
Sbjct: 433 DCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDC---SDMSCPNDCHQHGRCVNGM----C 485
Query: 515 ECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDP 574
C G+TG C+ D C N C+DG CVC +G+TG C + P+
Sbjct: 486 VCDDGYTGEDCR---DRQCPRDCSNRGLCVDG----QCVCEDGFTGPDC---AELSCPND 535
Query: 575 CH-YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGT 633
CH G C +G C+C G+ G C+ C S C G C D C C +G
Sbjct: 536 CHGQGRCVNG----QCVCHEGFMGKDCKE--QRCPSD-CHGQGRCVDGQ----CICHEGF 584
Query: 634 TGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCN 676
TG +C C S + G C+ C C GY+G C+
Sbjct: 585 TGLDC--GQHSCPSDCNNLGQCVSG----RCICNEGYSGEDCS 621
Score = 214 bits (545), Expect = 9e-55
Identities = 173/592 (29%), Positives = 239/592 (40%), Gaps = 147/592 (24%)
Query: 318 GYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACI 377
G CVC GW G +CSE ECP CHL CI
Sbjct: 171 GCGCVCEPGWKGPNCSEP------------------------ECPGN-----CHLRGRCI 201
Query: 378 SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFE 437
C C G+TG CSQ + C GKC+N +
Sbjct: 202 DGQ-----------------CICDDGFTGEDCSQ-----LACPSDCNDQGKCVNGV---- 235
Query: 438 CQCLQGYTGPRCEIDVNECVSNPCQND-ATCLDQIGEFQCICMPGYEGVHCEVNTDECAS 496
C C +GY G C E PC + TC+D + C+C G+ G C N C +
Sbjct: 236 CICFEGYAGADCS---REICPVPCSEEHGTCVDGL----CVCHDGFAGDDC--NKPLCLN 286
Query: 497 SPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTE 556
+ C + GRC+ E +C C GFTG C + C + +C++G TC C E
Sbjct: 287 N-CYNRGRCV----ENECVCDEGFTGEDCS---ELICPNDCFDRGRCING----TCYCEE 334
Query: 557 GYTGTHCEVDIDECDPDPCH-YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHG 615
G+TG C P CH G C++G C+C G+ G C C + C +
Sbjct: 335 GFTGEDCG---KPTCPHACHTQGRCEEG----QCVCDEGFAGVDCSE--KRCPAD-CHNR 384
Query: 616 GTCQDRDNAYLCFCLKGTTGPNC-EINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSM 674
G C D C C G TG +C E+ C + G C++ +C C+ GYTG
Sbjct: 385 GRCVDG----RCECDDGFTGADCGELK---CPNGCSGHGRCVNG----QCVCDEGYTGED 433
Query: 675 CNINIDECAGNPCHNGGTCEDGINGFTCRCPEGY--HDPTCLSEVNECNSNPCVHGACRD 732
C+ N CH+ G C +G C C +G+ +D + +S N+C+ HG C
Sbjct: 434 CS---QLRCPNDCHSRGRCVEG----KCVCEQGFKGYDCSDMSCPNDCHQ----HGRC-- 480
Query: 733 SLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI 792
+NG C CD G++G +C + +C + C N G C D C C +GF+GP+C
Sbjct: 481 -VNG-MCVCDDGYTGEDC--RDRQCPRD-CSNRGLCVDGQ----CVCEDGFTGPDC---A 528
Query: 793 NECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYES 852
N C QG C++ +C C + G C+ PS C G C +
Sbjct: 529 ELSCPNDCHGQGRCVNG----QCVCHEGFMGKDCK---EQRCPSDCHGQGRCVDGQ---- 577
Query: 853 FSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNC 904
C+C G+ G C S C + C + RC C GYSG +C
Sbjct: 578 --CICHEGFTGLDCG---QHSCPSDCNNLGQCVSG----RCICNEGYSGEDC 620
Score = 206 bits (524), Expect = 2e-52
Identities = 175/591 (29%), Positives = 230/591 (38%), Gaps = 127/591 (21%)
Query: 721 NSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR 780
++ P G S G C C+PGW G NC + EC N C G C D C C
Sbjct: 156 DTRPFCSGRGNFSTEGCGCVCEPGWKGPNC--SEPECPGN-CHLRGRCIDGQ----CICD 208
Query: 781 EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC-R 839
+GF+G +C C S+ C +QG C++ V C C Y GA C + P PC
Sbjct: 209 DGFTGEDCSQLA--CPSD-CNDQGKCVNGV----CICFEGYAGADCSREICPV---PCSE 258
Query: 840 NGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGY 899
G C CVC G+ G C + L+ C + C C C G+
Sbjct: 259 EHGTCVDG------LCVCHDGFAGDDCNKPL---CLNNCYNRGRCVENE----CVCDEGF 305
Query: 900 SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGAN 959
+G +C I C PN C + G C +G C C GF G +C C + +
Sbjct: 306 TGEDCSELI--C-PNDCFDRGRCINGT----CYCEEGFTG-------EDCGKPTCPHACH 351
Query: 960 CTDCVDSYTCTCPAGFSGIHC-ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
+ C C GF+G+ C E P + C N G CVDG C C GFTG+
Sbjct: 352 TQGRCEEGQCVCDEGFAGVDCSEKRCP----ADCHNRGRCVDG----RCECDDGFTGA-- 401
Query: 1019 QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH 1078
+C C +G + C + +C C +GYTG +C L C + C + G+C
Sbjct: 402 -----DCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQL--RCPND-CHSRGRC---- 449
Query: 1079 TQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
+ +C C G+ G C +SC C G CV+ C C GYT
Sbjct: 450 VEGKCVCEQGFKGYDCS--DMSC-----------PNDCHQHGRCVNG----MCVCDDGYT 492
Query: 1139 GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGG 1196
G C D +C P C N C D C C G+ G +C+E LS P C G
Sbjct: 493 GEDCRD--RQC-PRDCSNRGLCVD----GQCVCEDGFTGPDCAE-----LSCPNDCHGQG 540
Query: 1197 TCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1256
C++ +C C G G C+ + P D C G CVD C C
Sbjct: 541 RCVN----GQCVCHEGFMGKDCK----EQRCPSD-------CHGQGRCVDG----QCICH 581
Query: 1257 PGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESV 1307
GF G C S P D CV C C G++G C V
Sbjct: 582 EGFTGLDCGQH-----SCPSDCNNLGQCVSG----RCICNEGYSGEDCSEV 623
Score = 206 bits (524), Expect = 2e-52
Identities = 165/548 (30%), Positives = 216/548 (39%), Gaps = 112/548 (20%)
Query: 20 RGPRCSQPG--ETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTP--CKNAGTCH 75
+GP CS+P C G+C C+C F G C L+ P C + G C
Sbjct: 181 KGPNCSEPECPGNCHLRGRCIDGQ----CICDDGFTGEDCSQ----LACPSDCNDQGKC- 231
Query: 76 VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSG 135
+ C C G++G C + C GTC + C C G++G
Sbjct: 232 -------VNGVCICFEGYAGADCSREI---CPVPCSEEHGTC-----VDGLCVCHDGFAG 276
Query: 136 KSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC 195
C + P N C N G+C+ E C C F G C + + C P C G C
Sbjct: 277 DDCNK--PLCLNNCYNRGRCVENE----CVCDEGFTGEDCSELI--C---PNDCFDRGRC 325
Query: 196 HNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
N C C TG +C +P P C G C +C C GF G +C
Sbjct: 326 INGT----CYCEEGFTGEDCGKP---TCPHACHTQGRCEEG-----QCVCDEGFAGVDCS 373
Query: 256 ENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT 315
E CP + C N G CVDG C C +TG C E +C PN C G C N
Sbjct: 374 EK--RCPAD-CHNRGRCVDG----RCECDDGFTGADCGEL--KC---PNGCSGHGRCVNG 421
Query: 316 HGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDA 375
CVC G+TGEDCS+ C + R C C G G C +D
Sbjct: 422 Q----CVCDEGYTGEDCSQ-------LRCPNDCHSRGRCVEGKCVCEQGFKGYDC--SDM 468
Query: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435
N C++ C VNG +C C GYTG C +C C + G C++
Sbjct: 469 SCPNDCHQHGRC----VNG--MCVCDDGYTGEDCRD--RQC---PRDCSNRGLCVDG--- 514
Query: 436 FECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECA 495
+C C G+TGP +C C ND + QC+C G+ G C+ ++
Sbjct: 515 -QCVCEDGFTGP-------DCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCK---EQRC 563
Query: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT 555
S C GRC+D QC C GFTG C + C N +C+ G C+C
Sbjct: 564 PSDCHGQGRCVDG----QCICHEGFTGLDCG---QHSCPSDCNNLGQCVSG----RCICN 612
Query: 556 EGYTGTHC 563
EGY+G C
Sbjct: 613 EGYSGEDC 620
Score = 205 bits (521), Expect = 5e-52
Identities = 160/537 (29%), Positives = 227/537 (42%), Gaps = 112/537 (20%)
Query: 476 CICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAST 535
C+C PG++G +C + EC + C GRC+D QC C GFTG C +
Sbjct: 174 CVCEPGWKGPNC--SEPECPGN-CHLRGRCIDG----QCICDDGFTGEDCS---QLACPS 223
Query: 536 PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC--HYGSCKDGVATFTCLCRP 593
C + KC++G C+C EGY G C +I C P PC +G+C DG+ C+C
Sbjct: 224 DCNDQGKCVNG----VCICFEGYAGADCSREI--C-PVPCSEEHGTCVDGL----CVCHD 272
Query: 594 GYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG 653
G+ G C + C + C + G C + + C C +G TG +C + C + D G
Sbjct: 273 GFAGDDCNKPL--CLNN-CYNRGRCVENE----CVCDEGFTGEDCSELI--CPNDCFDRG 323
Query: 654 TCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC 713
C++ C CE G+TG C + CH G CE+G C C EG+ C
Sbjct: 324 RCINGT----CYCEEGFTGEDCG---KPTCPHACHTQGRCEEG----QCVCDEGFAGVDC 372
Query: 714 LSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTS 773
+ C ++ G C D +C+CD G++G +C +C N C G C +
Sbjct: 373 SEK--RCPADCHNRGRCVDG----RCECDDGFTGADC--GELKCP-NGCSGHGRCVNGQ- 422
Query: 774 GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPC 833
C C EG++G +C C N C ++G C++ KC C + G C +
Sbjct: 423 ---CVCDEGYTGEDCSQL--RCP-NDCHSRGRCVEG----KCVCEQGFKGYDCSDM---S 469
Query: 834 APSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE--------------VDINECVLSPCR 879
P+ C G C CVC G+ G+ C VD +CV
Sbjct: 470 CPNDCHQHGRCVNG------MCVCDDGYTGEDCRDRQCPRDCSNRGLCVD-GQCVCEDGF 522
Query: 880 HGASC------QNTHGGYRCH-----CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINT 928
G C + HG RC C G+ G++C+ + P+ CH G C DG
Sbjct: 523 TGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCK---EQRCPSDCHGQGRCVDGQ-- 577
Query: 929 AFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTP 985
C C GF G C + + C SD C N C S C C G+SG C +P
Sbjct: 578 --CICHEGFTGLDCGQ--HSCPSD-CNNLGQCV----SGRCICNEGYSGEDCSEVSP 625
Score = 161 bits (408), Expect = 7e-39
Identities = 165/582 (28%), Positives = 217/582 (37%), Gaps = 127/582 (21%)
Query: 910 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 969
D RP G T+G C C PG++G C E EC + G C+D C
Sbjct: 156 DTRPFCSGRGNFSTEGCG---CVCEPGWKGPNCSEP--ECPGNCHLRGR----CIDGQ-C 205
Query: 970 TCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQP 1029
C GF+G C S C + G CV+G+ C+C G+ G+ C ++ C
Sbjct: 206 ICDDGFTGEDCSQLA---CPSDCNDQGKCVNGV----CICFEGYAGADCSREI--CPVPC 256
Query: 1030 CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1089
GTC DG C C G+ G +C + C ++ C N G+C + C C G+
Sbjct: 257 SEEHGTCVDGL----CVCHDGFAGDDCNKPL--CLNN-CYNRGRC----VENECVCDEGF 305
Query: 1090 TGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDEC 1149
TG C E+ C G C++ C C+ G+TG ED
Sbjct: 306 TGEDCS------ELICPND-------CFDRGRCINGT----CYCEEGFTG---EDCGKPT 345
Query: 1150 SPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSC 1209
P C C + C C G+ GV+CSE+ C + C N G C+D +C C
Sbjct: 346 CPHACHTQGRCEEG----QCVCDEGFAGVDCSEK--RCPAD-CHNRGRCVD----GRCEC 394
Query: 1210 PRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVN 1269
G G C + C +G CV+ C C G+ GE C
Sbjct: 395 DDGFTGADC-----------GELKCPNGCSGHGRCVNG----QCVCDEGYTGEDCSQ--L 437
Query: 1270 ECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTA 1329
C N C +RG CV+ C C G G C + C C G C
Sbjct: 438 RC-PNDCHSRG--RCVEG----KCVCEQGFKGYDCSDM--SCPND-CHQHGRCVNG---- 483
Query: 1330 RGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASS 1389
+C C G+ G C + R C C N G C+ G C+C FTGP+C A
Sbjct: 484 ---MCVCDDGYTGEDCRD--RQCPR-DCSNRGLCVDGQ----CVCEDGFTGPDC---AEL 530
Query: 1390 PCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDY-SFGGGAGRDIPPPLIEEA 1448
C N C+ QG C +C+C F G C S G GR + I
Sbjct: 531 SC--PNDCHGQGRCVNG------QCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCI--- 579
Query: 1449 CELPECQEDAGNKVCSLQCNN-HAC---------GWDGGDCS 1480
C D G C CNN C G+ G DCS
Sbjct: 580 CHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCS 621
Score = 138 bits (347), Expect = 8e-32
Identities = 155/579 (26%), Positives = 218/579 (37%), Gaps = 135/579 (23%)
Query: 1002 INSFTCLCPPGFTGSYCQHDVNECDSQPCL--HGGTCQDGCGSYRCTCPQGYTGPNCQNL 1059
++S C G G Q D++P G +GCG C C G+ GPNC
Sbjct: 133 VSSLREQCTAG-AGCCLQPATGRLDTRPFCSGRGNFSTEGCG---CVCEPGWKGPNCSEP 188
Query: 1060 VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG 1119
C + C G+C +C C G+TG C + + C
Sbjct: 189 E--CPGN-CHLRGRC----IDGQCICDDGFTGEDCSQLACPSD-------------CNDQ 228
Query: 1120 GLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPC-QNGATCTDYLGGYSCKCVAGYHGV 1178
G CV+ C C GY G+ C E P PC + TC D L C C G+ G
Sbjct: 229 GKCVNGV----CICFEGYAGADCSR---EICPVPCSEEHGTCVDGL----CVCHDGFAGD 277
Query: 1179 NCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC 1238
+C++ + CL++ C N G C++ +C C G G +DC+ + P C
Sbjct: 278 DCNKPL--CLNN-CYNRGRCVE----NECVCDEGFTG-------EDCSELICPND----C 319
Query: 1239 FNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
F+ G C++ +C C GF GE C + C +G R + C C G
Sbjct: 320 FDRGRCING----TCYCEEGFTGEDCG---KPTCPHACHTQG------RCEEGQCVCDEG 366
Query: 1299 HTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCL 1358
G C C C N G C C+C GF GA C G L+C
Sbjct: 367 FAGVDCSE--KRCPAD-CHNRGRCVDGR-------CECDDGFTGADC-------GELKCP 409
Query: 1359 NG----GTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRC 1414
NG G C++G C+C +TG +C S N C+++G C +C
Sbjct: 410 NGCSGHGRCVNGQ----CVCDEGYTGEDC-----SQLRCPNDCHSRGRCVEG------KC 454
Query: 1415 LCPAKFNGLLCHILDYSFGGGA---GRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHA 1471
+C F G C D S GR + + C+ ED ++ C C+N
Sbjct: 455 VCEQGFKGYDCS--DMSCPNDCHQHGRCVNGMCV---CDDGYTGEDCRDRQCPRDCSNRG 509
Query: 1472 CGWDGGD-CSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCL----FDGFDCQRAEG 1526
DG C F P +C + L C +D H +C + C+ F G DC+
Sbjct: 510 LCVDGQCVCEDGFTGP--DCAE-LSCP---NDCHGQGRCVNGQCVCHEGFMGKDCK---- 559
Query: 1527 QCNPLYDQYC-KDHFSDGHCDQGCNSAECEWDGLDCAEH 1564
+Q C D G C G + GLDC +H
Sbjct: 560 ------EQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQH 592
Score = 138 bits (347), Expect = 8e-32
Identities = 122/420 (29%), Positives = 174/420 (41%), Gaps = 102/420 (24%)
Query: 21 GPRCSQPG--ETCLNGGKCEAANGTEACVCGGAFVGPRCQD---PNPCLSTPCKNAGTCH 75
G C++P C N G+C CVC F G C + PN C
Sbjct: 276 GDDCNKPLCLNNCYNRGRCVE----NECVCDEGFTGEDCSELICPNDCF----------- 320
Query: 76 VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSG 135
DR + C C GF+G C P + C G C+ E +C C G++G
Sbjct: 321 --DRGRCINGTCYCEEGFTGEDCGKPT----CPHACHTQGRCE-----EGQCVCDEGFAG 369
Query: 136 KSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC 195
C + C ++ C N G+C+ C C F G +CG+ C +G +
Sbjct: 370 VDCSEKR-CPAD-CHNRGRCVDGR----CECDDGFTGA-------DCGELK--CPNGCSG 414
Query: 196 HNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
H + +CVC +TG +C + + C P+ C + G C V +C C GF G +C
Sbjct: 415 HGRCVNGQCVCDEGYTGEDCSQ--LRC-PNDCHSRGRC-----VEGKCVCEQGFKGYDCS 466
Query: 256 ENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT 315
+ CP N+C G CV+G+ C C +TG+ C + +C P C N G C +
Sbjct: 467 DM--SCP-NDCHQHGRCVNGM----CVCDDGYTGEDCRDR--QC---PRDCSNRGLCVDG 514
Query: 316 HGGYNCVCVNGWTGEDCSENI--DDC-ASAACFHG-ATCHD------------------- 352
CVC +G+TG DC+E +DC C +G CH+
Sbjct: 515 Q----CVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQ 570
Query: 353 -RVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ 411
R C C G TGL C + +C S+ CN C V+G+ C C GY+G CS+
Sbjct: 571 GRCVDGQCICHEGFTGLDCGQH-SCPSD-CNNLGQC----VSGR--CICNEGYSGEDCSE 622
Score = 68.2 bits (165), Expect = 1e-10
Identities = 57/191 (29%), Positives = 77/191 (40%), Gaps = 38/191 (19%)
Query: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
C G+C NG CVC + G C+D C N G C D C C
Sbjct: 474 CHQHGRC--VNGM--CVCDDGYTGEDCRDRQ--CPRDCSNRGLC--------VDGQCVCE 519
Query: 91 LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA 150
GF+GP C + +C N C G C +C C G+ GK C++ C S+ C
Sbjct: 520 DGFTGPDCA---ELSC-PNDCHGQGRC-----VNGQCVCHEGFMGKDCKE-QRCPSD-CH 568
Query: 151 NGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATH 210
G+C+ + C C F G C Q + C P C + G C S RC+C +
Sbjct: 569 GQGRCVDGQ----CICHEGFTGLDCGQ--HSC---PSDCNNLGQCV----SGRCICNEGY 615
Query: 211 TGPNCERPYVP 221
+G +C P
Sbjct: 616 SGEDCSEVSPP 626
Score = 53.1 bits (126), Expect = 3e-06
Identities = 97/387 (25%), Positives = 136/387 (35%), Gaps = 90/387 (23%)
Query: 1203 NTYKCSCPRGTQGVHCEINVDDCNPPVD--PVSRSPKCFNNGTCVDQ---VGGYSCTCPP 1257
+ Y P G+Q C ++++ + D P S + F T + V + P
Sbjct: 52 HVYNIKLPVGSQ---CSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPR 108
Query: 1258 GFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
G DV E LS +N V + + +C AG G + +P
Sbjct: 109 RACGCAAAPDVKELLSR---LEELENLVSSLRE---QCTAG-AGCCLQPATGRLDTRPFC 161
Query: 1318 NGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGP 1377
+G + + G C C G++G C C C G CI G C+C
Sbjct: 162 SGR----GNFSTEGCGCVCEPGWKGPNCSEPE--CPG-NCHLRGRCIDGQ----CICDDG 210
Query: 1378 FTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG 1437
FTG +C A + C +QG C C+C F G AG
Sbjct: 211 FTGEDCSQLACP-----SDCNDQGKCVNGV------CIC---------------FEGYAG 244
Query: 1438 RDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPW--KNCTQSLQ 1495
D E C +P C E+ G V L C H G+ G DC N P NC +
Sbjct: 245 ADCS----REICPVP-CSEEHGTCVDGL-CVCHD-GFAGDDC----NKPLCLNNCYNRGR 293
Query: 1496 CWK---YFSDGHCDSQCNSAGCLFDGFDCQRA-EGQCNPLYDQYCKDHFSDGHCD----- 1546
C + +G C+ C D FD R G C YC++ F+ C
Sbjct: 294 CVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTC------YCEEGFTGEDCGKPTCP 347
Query: 1547 -----QG-CNSAECEWD----GLDCAE 1563
QG C +C D G+DC+E
Sbjct: 348 HACHTQGRCEEGQCVCDEGFAGVDCSE 374
Score = 46.6 bits (109), Expect = 3e-04
Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 25/125 (20%)
Query: 21 GPRCSQPG--ETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVD 78
GP C++ C G+C NG CVC F+G C++ + C G C
Sbjct: 524 GPDCAELSCPNDCHGQGRC--VNGQ--CVCHEGFMGKDCKEQR--CPSDCHGQGRC---- 573
Query: 79 RRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC 138
D C C GF+G C ++C ++ C N G C +C C G+SG+ C
Sbjct: 574 ----VDGQCICHEGFTGLDCG---QHSCPSD-CNNLGQC-----VSGRCICNEGYSGEDC 620
Query: 139 QQADP 143
+ P
Sbjct: 621 SEVSP 625
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 221 bits (562), Expect = 9e-57
Identities = 228/849 (26%), Positives = 336/849 (39%), Gaps = 153/849 (18%)
Query: 487 CEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQ---YDVDECASTP--CKNGA 541
C VN D C + G C++ + C C G+ Q D+DEC C G
Sbjct: 878 CTVNPDICGA------GHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG- 930
Query: 542 KCLDGPNTYTCVCTEGYT----GTHCEVDIDEC-DPDPCHYGSCKDGVATFTC-LCRPGY 595
+C + ++ C+C G+ GT+C +D+DEC PD C G C + V F C C GY
Sbjct: 931 RCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGY 989
Query: 596 T---GHHCETNINECSSQPCRHGGTCQDRDNAYLCF-CLKGTTGPNCE-INLDDCAS-SP 649
CE +I+EC + C + +Y C C +G G N + +++D+C +
Sbjct: 990 RMTQRGRCE-DIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNV 1048
Query: 650 CDSGTCLDKIDGYECACEPGYTGSM----CNINIDECA-GNPCHNGGTCEDGINGFTCRC 704
C +G C + Y C+C GYT + C +IDEC GN C NG C++ F C C
Sbjct: 1049 CANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNG-QCKNTEGSFRCTC 1106
Query: 705 PEGYHDPTC---LSEVNEC-NSNPCVHGACRDSLNGYKCDCDPGWS----GTNCDINNNE 756
+GY +++EC + + C HG CR++ ++C CD G+ G +C+ N
Sbjct: 1107 GQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 1166
Query: 757 CESNPCVNGGTCKDMTSGYVCTCREGF---SGPNCQTNINECA-SNPCLNQGTCIDDVAG 812
E G C + Y CTC +GF CQ +INEC C QG C++
Sbjct: 1167 LEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGS 1225
Query: 813 YKCNCLLPYT----GATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQ----GQ 864
+ C C ++ G TCE + + C + G C + SF C+C G+Q GQ
Sbjct: 1226 FHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAG--SFRCLCYQGFQAPQDGQ 1283
Query: 865 TCEVDINEC-VLSPCRHGASCQNTHGGYRCHC---------QAGYSGRNCETDIDDCRPN 914
C VD+NEC +LS A C+N G + C C G TD+D
Sbjct: 1284 GC-VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQ 1342
Query: 915 PCHNGGSCTDGINTA-FCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC---- 969
P C +N A CD + T EC C +GA D + + C
Sbjct: 1343 PKEEKKECYYNLNDASLCDNVLAPNVT-----KQECC---CTSGAGWGDNCEIFPCPVLG 1394
Query: 970 ------TCPAGFSGIHC--------ENNTPDCTESSCF-----NGGTCVDGINSFTCLCP 1010
CP G + N D E F G C++ + C C
Sbjct: 1395 TAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCK 1454
Query: 1011 PGFTGSYCQ---HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSP 1067
G + D++EC G C + GSY C C T P + P
Sbjct: 1455 QGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC----THPMVLDASEKRCIRP 1510
Query: 1068 CKNGGK----------CWQ-THTQYRCECP--------SGWTGLYCDVPSVSCEVAAQRQ 1108
++ + CW+ +Y C P + LY + + C + +
Sbjct: 1511 AESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD 1570
Query: 1109 GVDVARLCQ---------HG-GLCVDAGNTHHCRC-----QAGYTGSYCEDLVDECS-PS 1152
D A+LC +G VD + Q + S+ E +EC +
Sbjct: 1571 SDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILN 1630
Query: 1153 PCQNGATCTDYLGGYSCKCVAGYH---------GVNCSEEIDECLSHPCQNGGTCLDLPN 1203
C+NG C GY+C C GYH VN +E++ +S C+N C++
Sbjct: 1631 GCENG-RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS-LCKN-AKCINTDG 1687
Query: 1204 TYKCSCPRG 1212
+YKC C G
Sbjct: 1688 SYKCLCLPG 1696
Score = 209 bits (531), Expect = 4e-53
Identities = 232/877 (26%), Positives = 345/877 (39%), Gaps = 147/877 (16%)
Query: 376 CISNP--CNEGSNCDTNPVNGKAICTCPSGYTGPACSQ---DVDECSLGANPCEHAGKCI 430
C NP C G +C PV + C C GY + D+DEC+ + C G+C
Sbjct: 878 CTVNPDICGAG-HCINLPV--RYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQ-GRCE 933
Query: 431 NTLGSFECQCLQGYT----GPRCEIDVNECVSNPCQNDATCLDQIGEFQC-ICMPGYEGV 485
NT GSF C C G+ G C IDV+EC+ + C++ +G F+C C GY
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 992
Query: 486 H---CEVNTDECASSPCLHNGRCLDKINEFQC-ECPTGFTGHLCQ-YDVDECAS-TPCKN 539
CE + DEC + + +C++ +QC C GF G Q DVDEC C N
Sbjct: 993 QRGRCE-DIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCAN 1051
Query: 540 GAKCLDGPNTYTCVCTEGYTGT----HCEVDIDECDP-DPCHYGSCKDGVATFTCLCRPG 594
G C + +Y C C +GYT T HC DIDEC + C G CK+ +F C C G
Sbjct: 1052 G-DCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRCTCGQG 1109
Query: 595 Y----TGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTT----GPNCEINLDDCA 646
Y CE +I+EC + G C++ + ++ C C +G G +CE ++++C
Sbjct: 1110 YQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE-DINECL 1167
Query: 647 S--SPCDSGTCLDKIDGYECACEPGYT---GSMCNINIDECAG-NPCHNGGTCEDGINGF 700
S C G C++ Y+C C G+ C +I+EC C G C + F
Sbjct: 1168 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSF 1226
Query: 701 TCRCPEGYH---DPTCLSEVNECNSNPCV--HGACRDSLNGYKCDCDPGWS----GTNCD 751
C C +G+ D +++EC +N HG C ++ ++C C G+ G C
Sbjct: 1227 HCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC- 1285
Query: 752 INNNECESNPCVNGGT-CKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV 810
++ NECE V G C+++ ++C C + + T +C S + +D
Sbjct: 1286 VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTG--QCRSRTSTDLDVDVDQP 1343
Query: 811 AGYKCNCLLPYTGAT-CEVVLAP-------CAPSPCRNGGECRQSEDYESFSC------- 855
K C A+ C+ VLAP C S G C E F C
Sbjct: 1344 KEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC------EIFPCPVLGTAE 1397
Query: 856 ---VCPTGW-----------QGQTCEVDINECVL---SPCRHGASCQNTHGGYRCHCQAG 898
+CP G G D +EC+L C++G C NT GY C+C+ G
Sbjct: 1398 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGF-CLNTRPGYECYCKQG 1456
Query: 899 --YSGRNCET-DIDDCR-PNPCHNGGSC-TDGINTAFCD-----------CLPGFRGTFC 942
Y + D+D+C+ P+ C +G T+G FC C+ R
Sbjct: 1457 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCI---RPAES 1513
Query: 943 EEDINECA--SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1000
E I E D C + D Y C+ P TE C G +
Sbjct: 1514 NEQIEETDVYQDLCWEHLS-----DEYVCSRPL-------VGKQTTYTECCCLYG----E 1557
Query: 1001 GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSYRCTCPQGYTGPNCQNL 1059
LCP + Y Q + +G D Y + N
Sbjct: 1558 AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNS 1617
Query: 1060 VHWCDSSPCK--NG---GKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVAR 1114
+ C NG G+C + Y C+C + G + D ++C + ++
Sbjct: 1618 FEELQAEECGILNGCENGRCVRVQEGYTCDC---FDGYHLDTAKMTCVDVNECDELNNRM 1674
Query: 1115 LCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 1151
C++ ++ C C GY S D + C+P
Sbjct: 1675 SLCKNAKCINTDGSYKCLCLPGYVPS---DKPNYCTP 1708
Score = 208 bits (529), Expect = 6e-53
Identities = 223/860 (25%), Positives = 340/860 (39%), Gaps = 184/860 (21%)
Query: 395 KAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY---TGPRCEI 451
+A + S P +++EC++ + C AG CIN + C C +GY R +
Sbjct: 857 EASTSSASQVIAPTQVTEINECTVNPDICG-AGHCINLPVRYTCICYEGYRFSEQQRKCV 915
Query: 452 DVNEC--VSNPCQNDATCLDQIGEFQCICMPGY----EGVHCEVNTDECASSPCLHNGRC 505
D++EC V + C + C + G F CIC G+ EG +C ++ DEC G C
Sbjct: 916 DIDECTQVQHLC-SQGRCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHC 973
Query: 506 LDKINEFQCE-CPTGF--TGHLCQYDVDECASTPCKNGAKCLDGPNTYTCV-CTEGYTGT 561
++ + F+CE C +G+ T D+DEC + +C++ P +Y CV CTEG+ G
Sbjct: 974 VNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGW 1033
Query: 562 HCE-VDIDEC-DPDPCHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQPCRHG 615
+ + +D+DEC +P+ C G C + ++ C C GYT HC +I+EC
Sbjct: 1034 NGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVN 1092
Query: 616 GTCQDRDNAYLCFCLKG----TTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGY 670
G C++ + ++ C C +G CE ++D+C C G C + ++C C+ GY
Sbjct: 1093 GQCKNTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGY 1151
Query: 671 ----TGSMCNINIDECAGNP--CHNGGTCEDGINGFTCRCPEGYH--DPTCLSEVNEC-N 721
G C +I+EC + C G C + + C CP+G+ D ++NEC +
Sbjct: 1152 RASGLGDHCE-DINECLEDKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKTCQDINECEH 1209
Query: 722 SNPC-VHGACRDSLNGYKCDCDPGWS----GTNCDINNNECESNP-CVNGGTCKDMTSGY 775
C G C ++ + C C G+S G C+ + +EC +N C + G C + +
Sbjct: 1210 PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSF 1268
Query: 776 VCTCREGFSGP----NCQTNINEC--ASNPCLNQGTCIDDVAGYKCNC------LLPYTG 823
C C +GF P C ++NEC S C + C + + C C P TG
Sbjct: 1269 RCLCYQGFQAPQDGQGC-VDVNECELLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTG 1326
Query: 824 -------------------------------ATCEVVLAP-------CAPSPCRNGGECR 845
+ C+ VLAP C S G C
Sbjct: 1327 QCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC- 1385
Query: 846 QSEDYESFSC----------VCPTG-----------WQGQTCEVDINECVL---SPCRHG 881
E F C +CP G G D +EC+L C++G
Sbjct: 1386 -----EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG 1440
Query: 882 ASCQNTHGGYRCHCQAG--YSGRNCET-DIDDCR-PNPCHNGGSC--TDGINTAFCD--- 932
C NT GY C+C+ G Y + D+D+C+ P+ C + G C T+G FC
Sbjct: 1441 -FCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID-GQCVNTEGSYNCFCTHPM 1498
Query: 933 --------CLPGFRGT-----------FCEEDINE---CASDPCRNGANCTDCVDSY--- 967
C+ C E +++ C+ T+C Y
Sbjct: 1499 VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1558
Query: 968 ----TCTCPAGFSGIHCE-NNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDV 1022
CP S + + N P + VD +T P F +
Sbjct: 1559 WGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSF 1618
Query: 1023 NECDSQPC--LHG---GTCQDGCGSYRCTCPQGY---TGPNCQNLVHWCDS-----SPCK 1069
E ++ C L+G G C Y C C GY T V+ CD S CK
Sbjct: 1619 EELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCK 1678
Query: 1070 NGGKCWQTHTQYRCECPSGW 1089
N KC T Y+C C G+
Sbjct: 1679 N-AKCINTDGSYKCLCLPGY 1697
Score = 208 bits (529), Expect = 6e-53
Identities = 237/882 (26%), Positives = 345/882 (39%), Gaps = 182/882 (20%)
Query: 173 PTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP----------C 222
PT ++NEC P +C G C N Y C+C + +R V C
Sbjct: 869 PTQVTEINECTVNPDIC-GAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC 927
Query: 223 SPSPCQNGGTCRPTGDVTHECACLPGF----TGQNCEENIDDCPGNNCKNGGACVDGVNT 278
S C+N + + C C GF G NC + +D+C + G CV+ V
Sbjct: 928 SQGRCEN-------TEGSFLCICPAGFMASEEGTNCID-VDECLRPDVCGEGHCVNTVGA 979
Query: 279 YNCR-CPPEW--TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCV-CV---NGWTGED 331
+ C C + T + ED+DEC L P+ C + C N+ G Y CV C GW G+
Sbjct: 980 FRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPD-EQCVNSPGSYQCVPCTEGFRGWNGQ- 1036
Query: 332 CSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNC---D 388
C + +D+C C + S+ C C G T H + I + C +G+ C
Sbjct: 1037 CLD-VDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI-DECQQGNLCVNGQ 1094
Query: 389 TNPVNGKAICTCPSGYTGPACS---QDVDECSLGANPCEHAGKCINTLGSFECQCLQGY- 444
G CTC GY A +D+DEC + C H G+C NT GSF+C C QGY
Sbjct: 1095 CKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAH-GQCRNTEGSFQCVCDQGYR 1152
Query: 445 ---TGPRCEIDVNECVSNP--CQNDATCLDQIGEFQCICMPGY---EGVHCEVNTDECA- 495
G CE D+NEC+ + CQ C++ G + C C G+ + C+ + +EC
Sbjct: 1153 ASGLGDHCE-DINECLEDKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEH 1209
Query: 496 SSPCLHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECA-STPCKNGAKCLDGPNTY 550
C G CL+ F C C GF+ G C+ D+DEC +T C + C + ++
Sbjct: 1210 PGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSF 1268
Query: 551 TCVCTEGY----TGTHCEVDIDECD--PDPCHYGSCKDGVATFTCLC---------RPGY 595
C+C +G+ G C VD++EC+ C C++ +F C+C G
Sbjct: 1269 RCLCYQGFQAPQDGQGC-VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQ 1327
Query: 596 TGHHCETNINECSSQPCRHGGTC-QDRDNAYL-------------CFCLKGT-TGPNCEI 640
T+++ QP C + ++A L C C G G NCEI
Sbjct: 1328 CRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEI 1387
Query: 641 NLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNI-NIDECA--GNPCHNGGTCEDGI 697
+ + C K G+ A E N + DEC G G C +
Sbjct: 1388 FPCPVLGTAEFTEMC-PKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTR 1446
Query: 698 NGFTCRCPEG-YHDPTCLS--EVNEC-NSNPCVHGACRDSLNGYKCDCDPGW----SGTN 749
G+ C C +G Y+DP L +++EC + + C+ G C ++ Y C C S
Sbjct: 1447 PGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKR 1506
Query: 750 C---DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGP--NCQTNINECASNPCLNQG 804
C +N + E + ++ YVC S P QT EC C G
Sbjct: 1507 CIRPAESNEQIEETDVYQDLCWEHLSDEYVC------SRPLVGKQTTYTEC----CCLYG 1556
Query: 805 TC---------IDDVAGYKCNCLLPYTG-------------------------------- 823
+ D Y C +P TG
Sbjct: 1557 EAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLN 1616
Query: 824 ATCEVVLAPCA-PSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE---VDINEC-----V 874
+ E+ C + C NG R E Y +C C G+ T + VD+NEC
Sbjct: 1617 SFEELQAEECGILNGCENGRCVRVQEGY---TCDCFDGYHLDTAKMTCVDVNECDELNNR 1673
Query: 875 LSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPC 916
+S C++ A C NT G Y+C C GY + +PN C
Sbjct: 1674 MSLCKN-AKCINTDGSYKCLCLPGY--------VPSDKPNYC 1706
Score = 181 bits (459), Expect = 8e-45
Identities = 225/858 (26%), Positives = 316/858 (36%), Gaps = 176/858 (20%)
Query: 104 NACLTNPCRNGGTCDLLTLTEYKCRCPPGW----SGKSCQQADPCAS-NPCANGGQCLPF 158
N C NP G + Y C C G+ + C D C + G+C
Sbjct: 876 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 935
Query: 159 EASYICHCPPSF----HGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRC-VC----RAT 209
E S++C CP F G C DV+EC +P +C G C N VG++RC C R T
Sbjct: 936 EGSFLCICPAGFMASEEGTNCI-DVDEC-LRPDVCGEGH-CVNTVGAFRCEYCDSGYRMT 992
Query: 210 HTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECA-CLPGFTGQNCE-ENIDDCPGNNCK 267
G CE +PS C + G +++C C GF G N + ++D+C N
Sbjct: 993 QRG-RCEDIDECLNPSTCPDEQCVNSPG--SYQCVPCTEGFRGWNGQCLDVDECLEPNVC 1049
Query: 268 NGGACVDGVNTYNCRCPPEWTG----QYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC 323
G C + +Y C C +T ++C D+DECQ N C NG C NT G + C C
Sbjct: 1050 ANGDCSNLEGSYMCSCHKGYTRTPDHKHC-RDIDECQ-QGNLCVNG-QCKNTEGSFRCTC 1106
Query: 324 VNGW---TGEDCSENIDDCASA-ACFHGATCHDRVASFYCECPHG--RTGLLCHLNDA-- 375
G+ +D E+ID+C C HG C + SF C C G +GL H D
Sbjct: 1107 GQGYQLSAAKDQCEDIDECQHRHLCAHGQ-CRNTEGSFQCVCDQGYRASGLGDHCEDINE 1165
Query: 376 ------------CISNP------CNEGSNCDTNPV----------------------NGK 395
CI+ C +G D N G
Sbjct: 1166 CLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGS 1225
Query: 396 AICTCPSGYT----GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPR--- 448
C C G++ G C +D+DEC + C+ G C NT GSF C C QG+ P+
Sbjct: 1226 FHCVCQQGFSISADGRTC-EDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQ 1283
Query: 449 -CEIDVNEC--VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC 505
C +DVNEC +S C +A C + G F C+C E T +C S
Sbjct: 1284 GC-VDVNECELLSGVC-GEAFCENVEGSFLCVCAD--ENQEYSPMTGQCRSRTSTDLDVD 1339
Query: 506 LDKINEFQCECPTGFT-GHLC------QYDVDECASTPCKNGAKCLDGPNTYTC------ 552
+D+ E + EC LC EC C +GA D + C
Sbjct: 1340 VDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECC---CTSGAGWGDNCEIFPCPVLGTA 1396
Query: 553 ----VCTEG-----------YTGTHCEVDIDEC---DPDPCHYGSCKDGVATFTCLCRPG 594
+C +G G D DEC + C G C + + C C+ G
Sbjct: 1397 EFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG 1456
Query: 595 YTGHHCET---NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD 651
+ +++EC G C + + +Y CFC T P + P +
Sbjct: 1457 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC----THPMVLDASEKRCIRPAE 1512
Query: 652 SGTCLDKIDGYECACEPGYTGS-MCN-------INIDECAGNPCHNGGTCEDGINGFTCR 703
S +++ D Y+ C + +C+ EC C G G C
Sbjct: 1513 SNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC---CLYGEAW-----GMQCA 1564
Query: 704 -CPEGYHDPTCLSEVNECN------SNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNE 756
CP D CN P A D Y + DP + + E
Sbjct: 1565 LCPLKDSD----DYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEE 1620
Query: 757 CESNPC--VNG---GTCKDMTSGYVCTCREGFSGPNCQ---TNINEC-----ASNPCLNQ 803
++ C +NG G C + GY C C +G+ + ++NEC + C N
Sbjct: 1621 LQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN- 1679
Query: 804 GTCIDDVAGYKCNCLLPY 821
CI+ YKC CL Y
Sbjct: 1680 AKCINTDGSYKCLCLPGY 1697
Score = 181 bits (458), Expect = 1e-44
Identities = 171/645 (26%), Positives = 261/645 (40%), Gaps = 119/645 (18%)
Query: 711 PTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWSGTNCD---INNNEC-ESNPCVN 764
PT ++E+NEC NP C G C + Y C C G+ + ++ +EC + +
Sbjct: 869 PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCS 928
Query: 765 GGTCKDMTSGYVCTCREGF----SGPNCQTNINECASNPCLNQGTCIDDVAGYKCN-CLL 819
G C++ ++C C GF G NC +++EC +G C++ V ++C C
Sbjct: 929 QGRCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 987
Query: 820 PY---TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPT----GWQGQTCEVDINE 872
Y CE + PS C + +C S S+ CV T GW GQ +D++E
Sbjct: 988 GYRMTQRGRCEDIDECLNPSTCPD-EQCVNSPG--SYQCVPCTEGFRGWNGQC--LDVDE 1042
Query: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYS----GRNCETDIDDCRPNPCHNGGSCTDGINT 928
C+ C N G Y C C GY+ ++C DID+C+ G C + +
Sbjct: 1043 CLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DIDECQQGNLCVNGQCKNTEGS 1101
Query: 929 AFCDCLPGFRGTFCE---EDINECASDPCRNGANCTDCVDSYTCTCPAGFS----GIHCE 981
C C G++ + + EDI+EC C + S+ C C G+ G HCE
Sbjct: 1102 FRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE 1161
Query: 982 NNTPDCTESSCFNGGTCVDGINSFTCLCPPGF---TGSYCQHDVNECDSQPCLHG--GTC 1036
+ + S G C++ S+ C CP GF CQ D+NEC+ P L G G C
Sbjct: 1162 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECE-HPGLCGPQGEC 1219
Query: 1037 QDGCGSYRCTCPQGYT----GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW--- 1089
+ GS+ C C QG++ G C+++ +++ C + G C T +RC C G+
Sbjct: 1220 LNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 1279
Query: 1090 -TGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGN-------THHCRCQAG----- 1136
G C V CE+ + G + LCV A T CR +
Sbjct: 1280 QDGQGC-VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1338
Query: 1137 ----------------YTGSYCEDLVDECSPSPCQNGATCTDYLG-GYSCK--------- 1170
S C++++ +P+ + CT G G +C+
Sbjct: 1339 DVDQPKEEKKECYYNLNDASLCDNVL---APNVTKQECCCTSGAGWGDNCEIFPCPVLGT 1395
Query: 1171 ------CVAGYHGVNCSE-----------EIDECL---SHPCQNGGTCLDLPNTYKCSCP 1210
C G V E + DECL C+N G CL+ Y+C C
Sbjct: 1396 AEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCK 1454
Query: 1211 RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC 1255
+GT ++ D + DP S C +G CV+ G Y+C C
Sbjct: 1455 QGTYYDPVKLQCFDMDECQDPSS----CI-DGQCVNTEGSYNCFC 1494
Score = 166 bits (421), Expect = 2e-40
Identities = 205/815 (25%), Positives = 302/815 (37%), Gaps = 199/815 (24%)
Query: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFV----GPRCQDPNPCLSTP------CKNA-- 71
C+Q C + G+CE G+ C+C F+ G C D + CL C N
Sbjct: 920 CTQVQHLC-SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG 978
Query: 72 ----------------GTCHVVDR-------------RGVADYAC-SCALGFSG--PLCL 99
G C +D Y C C GF G CL
Sbjct: 979 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL 1038
Query: 100 TPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSG----KSCQQADPCASNPCANGGQC 155
+D N C NG +L Y C C G++ K C+ D C GQC
Sbjct: 1039 D-VDECLEPNVCANGDCSNLEG--SYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQC 1095
Query: 156 LPFEASYICHCPPSFHGPTCR---QDVNECGQKPGLCRHGGTCHNEVGSYRCVC----RA 208
E S+ C C + + +D++EC Q LC HG C N GS++CVC RA
Sbjct: 1096 KNTEGSFRCTCGQGYQLSAAKDQCEDIDEC-QHRHLCAHG-QCRNTEGSFQCVCDQGYRA 1153
Query: 209 THTGPNCERPYVPC--SPSPCQNGGTCRPTGDVTHECACLPGFT---GQNCEENIDDC-- 261
+ G +CE C S CQ G G +++C C GF + C++ I++C
Sbjct: 1154 SGLGDHCE-DINECLEDKSVCQRGDCINTAG--SYDCTCPDGFQLDDNKTCQD-INECEH 1209
Query: 262 PGNNCKNGGACVDGVNTYNCRCPPEWT----GQYCTEDVDECQLMPNACQNGGTCHNTHG 317
PG C G C++ +++C C ++ G+ C ED+DEC + C + G C NT G
Sbjct: 1210 PGL-CGPQGECLNTEGSFHCVCQQGFSISADGRTC-EDIDEC-VNNTVCDSHGFCDNTAG 1266
Query: 318 GYNCVCVNGWT----GEDCSENIDDCASAACFHG-ATCHDRVASFYCECP---------- 362
+ C+C G+ G+ C + +++C + G A C + SF C C
Sbjct: 1267 SFRCLCYQGFQAPQDGQGCVD-VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT 1325
Query: 363 ---HGRTGL----------------LCHLNDA----------------CISNPCNEGSNC 387
RT +LNDA C ++ G NC
Sbjct: 1326 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC 1385
Query: 388 DTNP--VNGKAICT--CPSGY----TGPACSQ-------DVDECSL-GANPCEHAGKCIN 431
+ P V G A T CP G G + S+ D DEC L G C++ G C+N
Sbjct: 1386 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN-GFCLN 1444
Query: 432 TLGSFECQCLQG-YTGP---RCEIDVNECVSNPCQNDATCLDQIGEFQCIC----MPGYE 483
T +EC C QG Y P +C D++EC D C++ G + C C +
Sbjct: 1445 TRPGYECYCKQGTYYDPVKLQC-FDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDAS 1503
Query: 484 GVHC--EVNTDECASSPCLHNGRCLDKIN-EFQCECP-----TGFTGHLCQYDVD---EC 532
C ++E ++ C + ++ E+ C P T +T C Y +C
Sbjct: 1504 EKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQC 1563
Query: 533 ASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCR 592
A P K+ + Y +C TG P + D +T
Sbjct: 1564 ALCPLKDS-------DDYAQLCNIPVTGRR----------QPYGRDALVDFSEQYTPEAD 1606
Query: 593 PGYTGHHCETNINECSSQPCR-----HGGTCQDRDNAYLCFCLKG----TTGPNCEINLD 643
P + + E ++ C G C Y C C G T C ++++
Sbjct: 1607 PYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC-VDVN 1665
Query: 644 DCAS-----SPCDSGTCLDKIDGYECACEPGYTGS 673
+C S C + C++ Y+C C PGY S
Sbjct: 1666 ECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS 1700
Score = 165 bits (417), Expect = 6e-40
Identities = 181/654 (27%), Positives = 270/654 (41%), Gaps = 121/654 (18%)
Query: 853 FSCVCPTGW----QGQTCEVDINEC--VLSPCRHGASCQNTHGGYRCHCQAGY----SGR 902
++C+C G+ Q + C VDI+EC V C G C+NT G + C C AG+ G
Sbjct: 897 YTCICYEGYRFSEQQRKC-VDIDECTQVQHLCSQGR-CENTEGSFLCICPAGFMASEEGT 954
Query: 903 NCETDIDDC-RPNPCHNGGSCTDGINTAFCD-CLPGFRGTF---CEEDINECASDPCRNG 957
NC D+D+C RP+ C G C + + C+ C G+R T CE DI+EC +
Sbjct: 955 NC-IDVDECLRPDVCGEG-HCVNTVGAFRCEYCDSGYRMTQRGRCE-DIDECLNPSTCPD 1011
Query: 958 ANCTDCVDSYTCT-CPAGFSGIHCEN-NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTG 1015
C + SY C C GF G + + + +C E + G C + S+ C C G+T
Sbjct: 1012 EQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTR 1071
Query: 1016 S----YCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSP 1067
+ +C+ D++EC G C++ GS+RCTC QGY C+++
Sbjct: 1072 TPDHKHCR-DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHL 1130
Query: 1068 CKNGGKCWQTHTQYRCECPSGW--TGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA 1125
C + G+C T ++C C G+ +GL CE + ++ +CQ G C++
Sbjct: 1131 CAH-GQCRNTEGSFQCVCDQGYRASGL-----GDHCEDI--NECLEDKSVCQRGD-CINT 1181
Query: 1126 GNTHHCRCQAGY---TGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVAGY----HG 1177
++ C C G+ C+D ++EC P C C + G + C C G+ G
Sbjct: 1182 AGSYDCTCPDGFQLDDNKTCQD-INECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 1240
Query: 1178 VNCSEEIDECLSHP-CQNGGTCLDLPNTYKCSCPRGTQ----GVHCEINVDDCNPPVDPV 1232
C E+IDEC+++ C + G C + +++C C +G Q G C ++V++C
Sbjct: 1241 RTC-EDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC-VDVNECE------ 1292
Query: 1233 SRSPKCFNNGTCVDQVGGYSCTCP---------PGFVGERCEGDVN-----------ECL 1272
S C C + G + C C G R D++ EC
Sbjct: 1293 LLSGVC-GEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECY 1351
Query: 1273 SNPCDARGTQNCV-QRVNDFHCECRAG-HTGRRCESVINGCKGKPCKNGGTCAVAS--NT 1328
N DA N + V C C +G G CE PC GT
Sbjct: 1352 YNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIF-------PCPVLGTAEFTEMCPK 1404
Query: 1329 ARGFICKCPAGFE----GATCENDARTC---GSLRCLNGGTCISGPRSPTCLC------- 1374
+GF+ PAG G DA C G C N G C++ C C
Sbjct: 1405 GKGFV---PAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQGTYYD 1460
Query: 1375 ---LGPFTGPECQFPAS---SPCLGGNPCYNQGTCEP-TSESPFYRCLCPAKFN 1421
L F ECQ P+S C+ YN P ++ RC+ PA+ N
Sbjct: 1461 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESN 1514
Score = 68.2 bits (165), Expect = 1e-10
Identities = 155/661 (23%), Positives = 215/661 (32%), Gaps = 170/661 (25%)
Query: 1009 CPPGF---TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY-------------- 1051
C PG+ ++CQ D+NEC Q G C + GSYRCTC G+
Sbjct: 612 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 670
Query: 1052 --------------TGPNCQN--LVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD 1095
+G C + VH C + GK W H + +CP T + +
Sbjct: 671 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCE---KCPLPGTAAFKE 727
Query: 1096 V--PSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSP 1153
+ + V+ + + G + V NT + + P P
Sbjct: 728 ICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNT--------------QPVAKSTHPPP 773
Query: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTY----KCSC 1209
+ L + HG +E E + P + LD T +
Sbjct: 774 LPAKEEPVEAL------TFSREHGPGVAE--PEVATAPPEKEIPSLDQEKTKLEPGQPQL 825
Query: 1210 PRGTQGVHCE-----INVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERC 1264
G +H I ++ +PPV PV +P+ + S P V E
Sbjct: 826 SPGISTIHLHPQFPGIVIEKTSPPV-PVEVAPEASTSSA--------SQVIAPTQVTE-- 874
Query: 1265 EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGH----TGRRCESVINGCKGKPCKNGG 1320
+NEC NP D G +C+ + C C G+ R+C + + + + G
Sbjct: 875 ---INECTVNP-DICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 930
Query: 1321 TCAVASNTARGFICKCPAGF----EGATC--------------ENDARTCGSLR------ 1356
C NT F+C CPAGF EG C + T G+ R
Sbjct: 931 RC---ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS 987
Query: 1357 ---------------CLNGGT-----CISGPRSPTCL-CLGPFTGPECQFPASSPCLGGN 1395
CLN T C++ P S C+ C F G Q CL N
Sbjct: 988 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN 1047
Query: 1396 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQ 1455
C N G C S Y C C + H RDI C +C+
Sbjct: 1048 VCAN-GDCSNLEGS--YMCSCHKGYTRTPDH--------KHCRDIDECQQGNLCVNGQCK 1096
Query: 1456 EDAGNKVCS------LQCNNHACGWDGGDCS---LNFNDPWKNCTQSLQC---WKYFSDG 1503
G+ C+ L C D +C L + +N S QC Y + G
Sbjct: 1097 NTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASG 1155
Query: 1504 HCDSQCNSAGCLFDGFDCQRAEGQC---NPLYDQYCKDHF--SDGHCDQGCNSAECEWDG 1558
D + CL D CQR G C YD C D F D Q N ECE G
Sbjct: 1156 LGDHCEDINECLEDKSVCQR--GDCINTAGSYDCTCPDGFQLDDNKTCQDIN--ECEHPG 1211
Query: 1559 L 1559
L
Sbjct: 1212 L 1212
Score = 50.8 bits (120), Expect = 2e-05
Identities = 87/351 (24%), Positives = 128/351 (36%), Gaps = 75/351 (21%)
Query: 110 PCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNP-----CANGGQCLPFEASYIC 164
PC NGG C + KC+CPP ++GK CQ AS P G+ L +
Sbjct: 406 PCMNGGQCS----SRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHST 461
Query: 165 HC---------------PPSF------HGPTCRQDVNEC-------GQKPGLCRHGGTCH 196
H PP+ H P +++ GQK + G +
Sbjct: 462 HTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQV 521
Query: 197 NEVGSYRCVCRATHTGPNCER--PYVPCSPSPCQNGGTCRPTGDVTHECA-CLPGFTGQN 253
+ G + H+ + ++ P+V + Q G + T + +C LPG + Q
Sbjct: 522 SYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQET--IGSQCGKALPGLSKQ- 578
Query: 254 CEENIDDCPG--------NNCKNGGACVDGVNTYN--CRCPPEW---TGQYCTEDVDECQ 300
+DC G N C+ + YN C P + +C +D++ECQ
Sbjct: 579 -----EDCCGTVGTSWGFNKCQKCPK-KPSYHGYNQMMECLPGYKRVNNTFC-QDINECQ 631
Query: 301 LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE 360
L C NG C NT G Y C C G+ + + C+ R+ S +
Sbjct: 632 LQ-GVCPNG-ECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCY-RLVSSGRQ 688
Query: 361 CPHGRTGLLCHLND--ACISNPCNEGSNCDTNPVNG----KAICTCPSGYT 405
C H L HL C S G +C+ P+ G K IC GYT
Sbjct: 689 CMH---PLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYT 736
Score = 47.4 bits (111), Expect = 2e-04
Identities = 29/65 (44%), Positives = 35/65 (53%), Gaps = 14/65 (21%)
Query: 932 DCLPGFR---GTFCEEDINECA-SDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC 987
+CLPG++ TFC+ DINEC C NG C + + SY CTC GF PD
Sbjct: 611 ECLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTCKIGFG--------PDP 660
Query: 988 TESSC 992
T SSC
Sbjct: 661 TFSSC 665
Score = 43.9 bits (102), Expect = 0.002
Identities = 76/321 (23%), Positives = 116/321 (36%), Gaps = 67/321 (20%)
Query: 148 PCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCR 207
PC NGGQC + C CPP+F G C+ V+ P L +H +G++ V
Sbjct: 406 PCMNGGQCSSRDK---CQCPPNFTGKLCQIPVHG-ASVPKLYQHSQQPGKALGTH--VIH 459
Query: 208 ATHTGP----NCERPYVPCSPSPCQNGGTCRPTGDV-THECACLPGFTGQNCEENIDDCP 262
+THT P + + V P+ P V H+ + + G TGQ +E P
Sbjct: 460 STHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKE---AQP 516
Query: 263 G-NNCKNGGACVDGVNTYNC---------------------RCPPEWTGQYCTEDVDECQ 300
G + G V T + RC E G C + +
Sbjct: 517 GQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLS 576
Query: 301 LMPNACQNGGT------CHN-----THGGYNCV--CVNGW--TGEDCSENIDDCASAACF 345
+ C GT C ++ GYN + C+ G+ ++I++C
Sbjct: 577 KQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVC 636
Query: 346 HGATCHDRVASFYCECPHG----RTGLLCHLNDACIS---NPC----NEGSNCDTNPVN- 393
C + + S+ C C G T C + IS PC + G C +P++
Sbjct: 637 PNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC-MHPLSV 695
Query: 394 --GKAICTCPSGYT-GPACSQ 411
K +C C G GP C +
Sbjct: 696 HLTKQLCCCSVGKAWGPHCEK 716
Score = 43.9 bits (102), Expect = 0.002
Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 13/119 (10%)
Query: 804 GTCIDDVAGYKCNCLLPYTGAT---CEVVLAPCAPSPCRNGGECRQSEDYESFSCV--CP 858
G C + G +C LP C V + C+ +C + Y ++ + C
Sbjct: 557 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQ---KCPKKPSYHGYNQMMECL 613
Query: 859 TGWQ--GQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP 915
G++ T DINEC L C NT G YRC C+ G+ + C P+P
Sbjct: 614 PGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVPDP 669
Score = 43.1 bits (100), Expect = 0.003
Identities = 34/80 (42%), Positives = 37/80 (46%), Gaps = 25/80 (31%)
Query: 177 QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTC-RP 235
Q VN CG G C HG + GS RC T P+C VP PCQNGG C RP
Sbjct: 164 QGVNVCG---GRCCHGWS--KAPGSQRC------TKPSC----VP----PCQNGGMCLRP 204
Query: 236 TGDVTHECACLPGFTGQNCE 255
C C PG G+ CE
Sbjct: 205 -----QLCVCKPGTKGKACE 219
Score = 40.4 bits (93), Expect = 0.023
Identities = 67/257 (26%), Positives = 93/257 (36%), Gaps = 44/257 (17%)
Query: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDG--CGSY------ 1043
C NGG C + C CPP FTG CQ V+ S P L+ + Q G G++
Sbjct: 407 CMNGGQCS---SRDKCQCPPNFTGKLCQIPVHGA-SVPKLYQHSQQPGKALGTHVIHSTH 462
Query: 1044 ----RCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD--VP 1097
T QG N+V+ P + Q H R + P+G
Sbjct: 463 TLPLTVTSQQGVKVKFPPNIVNIHVKHPPE---ASVQIHQVSRIDGPTGQKTKEAQPGQS 519
Query: 1098 SVSCEVAAQRQGVDVARLCQHGGLCVD----AGNTHHCRCQAGYTGSYC----------E 1143
VS + ++ + H + A T RC GS C E
Sbjct: 520 QVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQE 579
Query: 1144 DLVDECSPS----PCQNGATCTDYLG-GYSCKCVAGYHGVNCS--EEIDEC-LSHPCQNG 1195
D S CQ Y G +C+ GY VN + ++I+EC L C N
Sbjct: 580 DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPN- 638
Query: 1196 GTCLDLPNTYKCSCPRG 1212
G CL+ +Y+C+C G
Sbjct: 639 GECLNTMGSYRCTCKIG 655
Score = 39.7 bits (91), Expect = 0.038
Identities = 30/102 (29%), Positives = 40/102 (39%), Gaps = 19/102 (18%)
Query: 1034 GTCQDGCGSYRCTCPQGYTGPNCQNL------VHWCDSSPCKNGGKCWQTHTQYRCECPS 1087
G+CQ+ C T G L V C PC NGG+C ++ +C+CP
Sbjct: 368 GSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHL-PCMNGGQC---SSRDKCQCPP 423
Query: 1088 GWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH 1129
+TG C +P G V +L QH A TH
Sbjct: 424 NFTGKLCQIPV---------HGASVPKLYQHSQQPGKALGTH 456
Score = 37.7 bits (86), Expect = 0.15
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 5/50 (10%)
Query: 411 QDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNP 460
QD++EC L C + G+C+NT+GS+ C C G+ GP + + CV +P
Sbjct: 625 QDINECQL-QGVCPN-GECLNTMGSYRCTCKIGF-GP--DPTFSSCVPDP 669
Score = 37.0 bits (84), Expect = 0.25
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 5/72 (6%)
Query: 886 NTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEED 945
N GG CH + G T C P PC NGG C + C C PG +G CE
Sbjct: 167 NVCGGRCCHGWSKAPGSQRCTK-PSCVP-PCQNGGMC---LRPQLCVCKPGTKGKACETI 221
Query: 946 INECASDPCRNG 957
+ S P G
Sbjct: 222 AAQDTSSPVFGG 233
Score = 37.0 bits (84), Expect = 0.25
Identities = 26/75 (34%), Positives = 28/75 (37%), Gaps = 12/75 (16%)
Query: 128 RCPPGWSGKSCQQ--ADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCR----QDVNE 181
RC GWS Q P PC NGG CL +C C P G C QD +
Sbjct: 172 RCCHGWSKAPGSQRCTKPSCVPPCQNGGMCL---RPQLCVCKPGTKGKACETIAAQDTSS 228
Query: 182 ---CGQKPGLCRHGG 193
GQ PG G
Sbjct: 229 PVFGGQSPGAASSWG 243
Score = 36.6 bits (83), Expect = 0.33
Identities = 43/167 (25%), Positives = 64/167 (38%), Gaps = 23/167 (13%)
Query: 407 PACSQDVDEC-----SLGANPCEHAGKCINTLGSFEC-QCLQGY---TGPRCEIDVNECV 457
P S+ D C S G N C+ K + G + +CL GY C+ D+NEC
Sbjct: 573 PGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQ-DINECQ 631
Query: 458 SNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCL---HNGRCLDKINE-FQ 513
+ CL+ +G ++C C G+ + C P + G C ++ Q
Sbjct: 632 LQGVCPNGECLNTMGSYRCTCKIGFGP---DPTFSSCVPDPPVISEEKGPCYRLVSSGRQ 688
Query: 514 CECPTG--FTGHLCQYDVDECASTPCKNGAKC-LDGPNTYTCVCTEG 557
C P T LC V + C+ KC L G + +C G
Sbjct: 689 CMHPLSVHLTKQLCCCSVGKAWGPHCE---KCPLPGTAAFKEICPGG 732
Score = 36.6 bits (83), Expect = 0.33
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 7/81 (8%)
Query: 723 NPCVHGACRDSLNGYK--CDCDPGWSGTNCDI--NNNECESNPCVNGGTCKDMTSGYVCT 778
N C + S +GY +C PG+ N + NEC+ G C + Y CT
Sbjct: 592 NKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCT 651
Query: 779 CREGFSGPNCQTNINECASNP 799
C+ GF GP+ + C +P
Sbjct: 652 CKIGF-GPD--PTFSSCVPDP 669
Score = 35.8 bits (81), Expect = 0.56
Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 17/88 (19%)
Query: 205 VCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGN 264
+C+ T T +C+ + C+ G T + H L T N I P
Sbjct: 360 ICKVTCTKGSCQ--------NSCEKGNTTTLISENGHAADTL---TATNFRVVICHLP-- 406
Query: 265 NCKNGGACVDGVNTYNCRCPPEWTGQYC 292
C NGG C + C+CPP +TG+ C
Sbjct: 407 -CMNGGQCS---SRDKCQCPPNFTGKLC 430
Score = 35.8 bits (81), Expect = 0.56
Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Query: 498 PCLHNGRCLDKINEFQCECPTGFTGHLCQYDV 529
PC++ G+C + +C+CP FTG LCQ V
Sbjct: 406 PCMNGGQCSSRD---KCQCPPNFTGKLCQIPV 434
Score = 35.4 bits (80), Expect = 0.73
Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 1191 PCQNGGTCLDLPNTYKCSCPRGTQGVHCE-INVDDCNPPV 1229
PCQNGG CL C C GT+G CE I D + PV
Sbjct: 194 PCQNGGMCL---RPQLCVCKPGTKGKACETIAAQDTSSPV 230
Score = 35.0 bits (79), Expect = 0.95
Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 6/51 (11%)
Query: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGAS 883
C P PC+NGG C + + CVC G +G+ CE + SP G S
Sbjct: 191 CVP-PCQNGGMCLRPQ-----LCVCKPGTKGKACETIAAQDTSSPVFGGQS 235
Score = 34.3 bits (77), Expect = 1.6
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 110 PCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQ 154
PC+NGG C L C C PG GK+C+ ++ GGQ
Sbjct: 194 PCQNGGMC----LRPQLCVCKPGTKGKACETIAAQDTSSPVFGGQ 234
Score = 34.3 bits (77), Expect = 1.6
Identities = 25/98 (25%), Positives = 38/98 (38%), Gaps = 15/98 (15%)
Query: 744 GWSGTNCDINN-NECESNPCVNGGTCKDMTSGYVCTCREGFSGPN---CQTNINECASNP 799
G GT+ N +C P +G + C G+ N CQ +INEC
Sbjct: 583 GTVGTSWGFNKCQKCPKKPSYHG-------YNQMMECLPGYKRVNNTFCQ-DINECQLQG 634
Query: 800 CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSP 837
G C++ + Y+C C + G + + C P P
Sbjct: 635 VCPNGECLNTMGSYRCTCKI---GFGPDPTFSSCVPDP 669
Score = 33.9 bits (76), Expect = 2.1
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 17/81 (20%)
Query: 419 GANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL-DQIGEFQCI 477
G N C G+C + G + Q T P C PCQN CL Q+ C+
Sbjct: 165 GVNVC--GGRCCH--GWSKAPGSQRCTKPSCV--------PPCQNGGMCLRPQL----CV 208
Query: 478 CMPGYEGVHCEVNTDECASSP 498
C PG +G CE + SSP
Sbjct: 209 CKPGTKGKACETIAAQDTSSP 229
Score = 33.5 bits (75), Expect = 2.8
Identities = 21/71 (29%), Positives = 25/71 (35%), Gaps = 11/71 (15%)
Query: 1316 CKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCL 1375
C+ G T + S F C L C+NGG C S + C C
Sbjct: 374 CEKGNTTTLISENGHAADTLTATNFRVVICH--------LPCMNGGQCSSRDK---CQCP 422
Query: 1376 GPFTGPECQFP 1386
FTG CQ P
Sbjct: 423 PNFTGKLCQIP 433
Score = 33.1 bits (74), Expect = 3.6
Identities = 62/271 (22%), Positives = 90/271 (33%), Gaps = 45/271 (16%)
Query: 987 CTESSCF----NGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGS 1042
CT+ SC NGG C + C+C PG G C+ + S P + GG S
Sbjct: 186 CTKPSCVPPCQNGGMC---LRPQLCVCKPGTKGKACETIAAQDTSSP-VFGGQSPGAASS 241
Query: 1043 Y--------RCTCPQGYTGPNCQNLVHWCDS-SPCKNGGKCWQTHTQYR------CECPS 1087
+ + + T P + + P + G Q H+Q
Sbjct: 242 WGPPEQAAKHTSSKKADTLPRVSPVAQMTLTLKPKPSVGLPQQIHSQVTPLSSQSVVIHH 301
Query: 1088 GWTGLYCDVPS-------VSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS 1140
G T Y P +S E + + G R Q + H R + +T S
Sbjct: 302 GQTQEYVLKPKYFPAQKGISGEQSTE--GSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPS 359
Query: 1141 YCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNC--SEEIDECLSH-PCQNGGT 1197
C+ C+ CQN G + H + + + H PC NGG
Sbjct: 360 ICKVT---CTKGSCQNSCE----KGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQ 412
Query: 1198 CLDLPNTYKCSCPRGTQGVHCEINVDDCNPP 1228
C + KC CP G C+I V + P
Sbjct: 413 C---SSRDKCQCPPNFTGKLCQIPVHGASVP 440
Score = 33.1 bits (74), Expect = 3.6
Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 14/47 (29%)
Query: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGAS 883
PC NGG+C + C CP + G+ C++ + HGAS
Sbjct: 406 PCMNGGQCSSRD-----KCQCPPNFTGKLCQIPV---------HGAS 438
Score = 32.7 bits (73), Expect = 4.7
Identities = 36/130 (27%), Positives = 47/130 (36%), Gaps = 20/130 (15%)
Query: 1024 ECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPN---CQNLVHWCDSSPCKNGGKCWQTHTQ 1080
+C +P HG + C GY N CQ++ C NG +C T
Sbjct: 596 KCPKKPSYHGY-------NQMMECLPGYKRVNNTFCQDINECQLQGVCPNG-ECLNTMGS 647
Query: 1081 YRCECPSG------WTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQ 1134
YRC C G ++ D P +S E + V R C H L V C C
Sbjct: 648 YRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMH-PLSVHL-TKQLCCCS 705
Query: 1135 AGYT-GSYCE 1143
G G +CE
Sbjct: 706 VGKAWGPHCE 715
Score = 32.3 bits (72), Expect = 6.1
Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 3/43 (6%)
Query: 611 PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG 653
PC++GG C LC C GT G CE SSP G
Sbjct: 194 PCQNGGMCL---RPQLCVCKPGTKGKACETIAAQDTSSPVFGG 233
Score = 32.0 bits (71), Expect = 8.0
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 23/91 (25%)
Query: 725 CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN------------PCVNGGTCKDMT 772
C G+C++S C+ G + T N + ++ PC+NGG C +
Sbjct: 365 CTKGSCQNS-------CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQC---S 414
Query: 773 SGYVCTCREGFSGPNCQTNINECASNPCLNQ 803
S C C F+G CQ ++ AS P L Q
Sbjct: 415 SRDKCQCPPNFTGKLCQIPVHG-ASVPKLYQ 444
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.461
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 130,853,409
Number of Sequences: 37866
Number of extensions: 7737180
Number of successful extensions: 75771
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 589
Number of HSP's successfully gapped in prelim test: 852
Number of HSP's that attempted gapping in prelim test: 22662
Number of HSP's gapped (non-prelim): 17140
length of query: 2555
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2436
effective length of database: 13,741,464
effective search space: 33474206304
effective search space used: 33474206304
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.